A0A087XNB6_POEFO Loading...

Tyrosinase

AlphaFold DB , UniProt , Accession A0A087XNB6, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 540 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M41.9Very low33Very low243 Ų243158.5 Ų158.5100%1.19785%0.848SS**  087.10-74.7-177.4-80.400109.2
2K31.3Very low32.5Very low197 Ų197157.1 Ų157.186%0.85783%0.832SS**  trans-150.3130.1171.1-78.3-169.3177.2177.60109
3N29.4Very low32.4Very low155 Ų155158 Ų15883%0.82984%0.836SS**  trans78.494.1152.2-57.5-3.4000119.1
4L36.6Very low32.2Very low173 Ų173156.8 Ų156.891%0.90683%0.826SS**  trans-120.4101.7153.9-153.291000107.4
5F33.1Very low32Very low214 Ų214151.5 Ų151.594%0.93982%0.824SS**  trans-153.3112.6166.2-93.8-85.7000103
6G32.3Very low31.8Very low66 Ų66149.3 Ų149.368%0.6882%0.817SS**  113.682.466.500000105.6
7S31.1Very low31.8Very low132 Ų132145.8 Ų145.892%0.92380%0.804SS**  trans-86.9117.5176.2-82.50000109.8
8V32.9Very low32Very low130 Ų130137.9 Ų137.979%0.78876%0.761SS**  trans-65.2138.5-175.8169.70000111.3L10V8-L10 PolarHBondContact O-N 2.95Å
9V33.7Very low32.1Very low109 Ų109130.7 Ų130.766%0.66172%0.721SS**  trans-45.6115.9168.3175.30000110.6F11V9-F11 HydrophobicContact CG1-CD2 3.71Å; V9-F11 HydrophobicContact CG1-CE2 3.9Å; V9-F11 HydrophobicContact CG1-CG 4.48Å; V9-F11 PolarHBondContact O-N 3.37Å
10L29.4Very low33.7Very low151 Ų151124.3 Ų124.379%0.79169%0.686SS**  trans-80.794.6166.6-147.586.3000107.3V8 H12V8-L10 PolarHBondContact O-N 2.95Å; L10-H12 PolarHBondContact O-N 3.47Å; L10-H12 VanDerWaalsContact O-N 3.11Å
11F31.3Very low36.3Very low174 Ų174118.5 Ų118.576%0.76365%0.654SS**  trans-62110.3166.5-95.6-89.7000108.2V9 L13V9-F11 HydrophobicContact CG1-CD2 3.71Å; V9-F11 HydrophobicContact CG1-CE2 3.9Å; V9-F11 HydrophobicContact CG1-CG 4.48Å; V9-F11 PolarHBondContact O-N 3.37Å; F11-L13 VanDerWaalsContact C-N 3.28Å; F11-L13 PolarHBondContact O-N 3.39Å
12H27.1Very low38.7Very low141 Ų141107 Ų10765%0.65360%0.597SS**  trans-66.792.4159.7-87.88.4000108.4L10 M14L10-H12 PolarHBondContact O-N 3.47Å; L10-H12 VanDerWaalsContact O-N 3.11Å; H12-M14 PolarHBondContact O-N 2.92Å
13L31.2Very low41.7Very low169 Ų16999.9 Ų99.989%0.88557%0.565SS**  trans-70.477153.7-79.8159.1000107.6F11F11-L13 VanDerWaalsContact C-N 3.28Å; F11-L13 PolarHBondContact O-N 3.39Å
14M29.2Very low44.8Very low141 Ų14196.2 Ų96.270%0.69555%0.549SS*.  trans-94.9102.4156-69.9-166.2-174.600106.1H12 V16H12-M14 PolarHBondContact O-N 2.92Å; M14-V16 WeakPolarHBondContact O-CG2 3.41Å; M14-V16 PolarHBondContact O-N 3.5Å
15G29.5Very low47.6Very low77 Ų7788.1 Ų88.179%0.79451%0.507SS*.  trans-59.9116.8172.800000108.9C17G15-C17 PolarHBondContact O-N 3.29Å
16V28.7Very low50.5Low117 Ų11778.1 Ų78.171%0.70946%0.464SS*.  trans-88.296.6179.7-158.50000107.3M14 S18M14-V16 WeakPolarHBondContact O-CG2 3.41Å; M14-V16 PolarHBondContact O-N 3.5Å; V16-S18 PolarHBondContact O-OG 3.06Å
17C31.2Very low53.4Low89 Ų8977.6 Ų77.660%0.60145%0.446SS*.  trans-65.4147.4166.2-73.70000109.9G15G15-C17 PolarHBondContact O-N 3.29Å
18S36.1Very low56.4Low5 Ų573.4 Ų73.44%0.03542%0.417CS..  trans-143135.2-159.7-73.40000108.3V16 R23 V151 F169 S170 D171V16-S18 PolarHBondContact O-OG 3.06Å; S18-R23 PolarHBondContact OG-NH1 3.47Å; S18-V151 VanDerWaalsContact C-CG1 3.42Å; S18-V151 VanDerWaalsContact CB-CG2 3.49Å; S18-V151 WeakPolarHBondContact O-CB 3.48Å; S18-V151 WeakPolarHBondContact O-CG1 3.39Å; S18-F169 CarbonylContact O-C 3.5Å; S18-F169 WeakPolarHBondContact O-CB 3.45Å; S18-S170 CarbonylContact O-C 3.6Å; S18-S170 PolarHBondContact O-N 3.49Å; S18-S170 VanDerWaalsContact O-N 3.13Å; S18-D171 WeakPolarHBondContact CB-OD1 3.46Å
19S34Very low59.3Low0 Ų071.6 Ų71.60%040%0.399CS..  trans-122.7176.4-178.480.10000124.2F21 A26 Y150 V151 F169S19-F21 CarbonylContact C-O 3.09Å; S19-F21 VanDerWaalsContact C-O 3.23Å; S19-F21 CarbonylContact O-C 3.32Å; S19-F21 PolarHBondContact O-N 2.9Å; S19-F21 VanDerWaalsContact O-N 3.09Å; S19-F21 WeakPolarHBondContact OG-CA 3.42Å; S19-F21 WeakPolarHBondContact OG-CB 3.33Å; S19-F21 WeakPolarHBondContact OG-CD2 3.46Å; S19-F21 PolarHBondContact OG-N 3.41Å; S19-F21 PolarHBondContact OG-O 2.87Å; S19-A26 WeakPolarHBondContact OG-CA 3.46Å; S19-A26 WeakPolarHBondContact OG-CB 3.35Å; S19-Y150 CarbonylContact O-C 3.59Å; S19-V151 VanDerWaalsContact C-N 3.29Å; S19-V151 CarbonylContact C-O 3.58Å; S19-V151 VanDerWaalsContact CA-CG2 3.46Å; S19-V151 CarbonylContact O-C 3.58Å; S19-V151 VanDerWaalsContact O-C 3.31Å; S19-V151 WeakPolarHBondContact O-CA 3.45Å; S19-V151 WeakPolarHBondContact O-CB 3.42Å; S19-V151 WeakPolarHBondContact O-CG2 3.34Å; S19-V151 PolarHBondContact O-N 2.93Å; S19-F169 VanDerWaalsContact CB-CB 3.45Å; S19-F169 VanDerWaalsContact CB-CE1 3.42Å
20Q63.3Low62.2Low2 Ų266.6 Ų66.61%0.00937%0.37CS..SBendtrans-59-26174.3164.172.718.900112.7Y150 V151 W180 I181 P431Q20-Y150 VanDerWaalsContact O-CD1 3.29Å; Q20-Y150 WeakPolarHBondContact O-CD1 3.42Å; Q20-V151 WeakPolarHBondContact CA-O 3.41Å; Q20-V151 WeakPolarHBondContact CB-O 3.34Å; Q20-V151 PolarHBondContact N-O 3.35Å; Q20-W180 HydrophobicContact CB-CE3 4.37Å; Q20-W180 HydrophobicContact CB-CH2 4.33Å; Q20-W180 HydrophobicContact CB-CZ3 3.87Å; Q20-W180 HydrophobicContact CG-CE3 4.3Å; Q20-W180 HydrophobicContact CG-CH2 4.42Å; Q20-W180 HydrophobicContact CG-CZ3 3.67Å; Q20-I181 VanDerWaalsContact NE2-CG1 3.29Å; Q20-P431 HydrophobicContact CG-CG 4.43Å; Q20-P431 PolarHBondContact NE2-O 2.88Å; Q20-P431 VanDerWaalsContact NE2-O 3.16Å
21F88.4Confident65.3Low3 Ų359.4 Ų59.41%0.01333%0.332CS..SBendtrans-72.6138.1164.9-45.1-80000108S19 R23 C25 W81 F85 F86 F169 L433S19-F21 CarbonylContact C-O 3.09Å; S19-F21 VanDerWaalsContact C-O 3.23Å; S19-F21 CarbonylContact O-C 3.32Å; S19-F21 PolarHBondContact O-N 2.9Å; S19-F21 VanDerWaalsContact O-N 3.09Å; S19-F21 WeakPolarHBondContact OG-CA 3.42Å; S19-F21 WeakPolarHBondContact OG-CB 3.33Å; S19-F21 WeakPolarHBondContact OG-CD2 3.46Å; S19-F21 PolarHBondContact OG-N 3.41Å; S19-F21 PolarHBondContact OG-O 2.87Å; F21-R23 PolarHBondContact O-N 2.95Å; F21-C25 HydrophobicContact CB-CB 4.41Å; F21-W81 AromaticContact CE1-CH2 3.54Å; F21-W81 HydrophobicContact CE1-CH2 3.54Å; F21-W81 HydrophobicContact CE1-CZ2 4.27Å; F21-W81 HydrophobicContact CE1-CZ3 4.3Å; F21-W81 AromaticContact CZ-CH2 3.98Å; F21-W81 HydrophobicContact CZ-CH2 3.98Å; F21-W81 HydrophobicContact CZ-CZ3 4.47Å; F21-F85 HydrophobicContact CE1-CB 3.94Å; F21-F85 HydrophobicContact CE1-CD1 4.21Å; F21-F85 AromaticContact CE1-CD2 3.94Å; F21-F85 HydrophobicContact CE1-CD2 3.94Å; F21-F85 AromaticContact CE1-CG 3.76Å; F21-F85 HydrophobicContact CE1-CG 3.76Å; F21-F85 AromaticContact CE2-CD1 3.85Å; F21-F85 HydrophobicContact CE2-CD1 3.85Å; F21-F85 AromaticContact CE2-CE1 3.94Å; F21-F85 HydrophobicContact CE2-CE1 3.94Å; F21-F85 HydrophobicContact CE2-CG 4.24Å; F21-F85 HydrophobicContact CE2-CZ 4.4Å; F21-F85 HydrophobicContact CZ-CB 4.09Å; F21-F85 AromaticContact CZ-CD1 3.5Å; F21-F85 HydrophobicContact CZ-CD1 3.5Å; F21-F85 VanDerWaalsContact CZ-CD1 3.5Å; F21-F85 AromaticContact CZ-CD2 3.59Å; F21-F85 HydrophobicContact CZ-CD2 3.59Å; F21-F85 AromaticContact CZ-CE1 3.74Å; F21-F85 HydrophobicContact CZ-CE1 3.74Å; F21-F85 AromaticContact CZ-CE2 3.81Å; F21-F85 HydrophobicContact CZ-CE2 3.81Å; F21-F85 AromaticContact CZ-CG 3.43Å; F21-F85 HydrophobicContact CZ-CG 3.43Å; F21-F85 VanDerWaalsContact CZ-CG 3.43Å; F21-F85 AromaticContact CZ-CZ 3.89Å; F21-F85 HydrophobicContact CZ-CZ 3.89Å; F21-F86 HydrophobicContact CB-CE2 3.94Å; F21-F86 HydrophobicContact CB-CZ 4.27Å; F21-F86 AromaticContact CD1-CD2 3.87Å; F21-F86 HydrophobicContact CD1-CD2 3.87Å; F21-F86 AromaticContact CD1-CE2 3.25Å; F21-F86 HydrophobicContact CD1-CE2 3.25Å; F21-F86 HydrophobicContact CD1-CZ 4.29Å; F21-F86 HydrophobicContact CD2-CE2 4.42Å; F21-F86 HydrophobicContact CE1-CD2 4.16Å; F21-F86 AromaticContact CE1-CE2 3.77Å; F21-F86 HydrophobicContact CE1-CE2 3.77Å; F21-F86 AromaticContact CG-CE2 3.62Å; F21-F86 HydrophobicContact CG-CE2 3.62Å; F21-F86 HydrophobicContact CG-CZ 4.27Å; F21-F169 HydrophobicContact CD2-CD1 4.41Å; F21-F169 AromaticContact CD2-CE1 3.52Å; F21-F169 HydrophobicContact CD2-CE1 3.52Å; F21-F169 AromaticContact CD2-CZ 3.89Å; F21-F169 HydrophobicContact CD2-CZ 3.89Å; F21-F169 AromaticContact CE2-CE1 3.66Å; F21-F169 HydrophobicContact CE2-CE1 3.66Å; F21-F169 HydrophobicContact CE2-CZ 4.2Å; F21-L433 HydrophobicContact CB-CD1 4.41Å; F21-L433 HydrophobicContact CD1-CD1 3.28Å; F21-L433 HydrophobicContact CE1-CD1 3.89Å; F21-L433 HydrophobicContact CG-CD1 4.33Å
22P93.9Very high68.4Low1 Ų157.6 Ų57.61%0.00632%0.32CS..  trans-37.4129.3177.6-28.731.6000111.6P24 C25 A26 P38 F99 D149 Y150P22-P24 WeakPolarHBondContact O-CD 3.42Å; P22-C25 WeakPolarHBondContact O-CA 3.27Å; P22-C25 WeakPolarHBondContact O-CB 3.47Å; P22-C25 PolarHBondContact O-N 3.24Å; P22-A26 PolarHBondContact O-N 3.5Å; P22-P38 HydrophobicContact CB-CG 4.26Å; P22-F99 HydrophobicContact CB-CB 4.07Å; P22-F99 HydrophobicContact CB-CD1 4.24Å; P22-F99 HydrophobicContact CB-CD2 3.49Å; P22-F99 VanDerWaalsContact CB-CD2 3.49Å; P22-F99 HydrophobicContact CB-CE2 3.92Å; P22-F99 HydrophobicContact CB-CG 3.66Å; P22-F99 HydrophobicContact CB-CZ 4.47Å; P22-F99 HydrophobicContact CG-CB 3.33Å; P22-F99 HydrophobicContact CG-CD1 4.22Å; P22-F99 HydrophobicContact CG-CD2 3.77Å; P22-F99 HydrophobicContact CG-CG 3.51Å; P22-D149 CarbonylContact C-O 3.44Å; P22-D149 WeakPolarHBondContact CA-O 3.38Å; P22-Y150 HydrophobicContact CG-CE1 4.07Å
23R93.6Very high71.6Confident49 Ų4953.9 Ų53.919%0.18531%0.308CS..G310 helixtrans-40.1-42.9-174.3-78.9177-171.5-93.9-8.4113.9S18 F21 C25 A26 N147 P148 D149 V151 D171S18-R23 PolarHBondContact OG-NH1 3.47Å; F21-R23 PolarHBondContact O-N 2.95Å; R23-C25 PolarHBondContact O-N 3.43Å; R23-A26 WeakPolarHBondContact O-CB 3.28Å; R23-A26 PolarHBondContact O-N 2.82Å; R23-A26 VanDerWaalsContact O-N 3.15Å; R23-N147 PolarHBondContact NE-O 2.94Å; R23-N147 PolarHBondContact NH2-O 3.2Å; R23-P148 WeakPolarHBondContact CD-O 3.39Å; R23-P148 PolarHBondContact NE-O 3.16Å; R23-D149 PolarHBondContact N-O 2.79Å; R23-V151 HydrophobicContact CB-CG2 4.38Å; R23-V151 HydrophobicContact CG-CG2 3.2Å; R23-D171 IonicContact CZ-OD1 3.72Å; R23-D171 VanDerWaalsContact CZ-OD1 3.26Å; R23-D171 IonicContact NH1-OD1 3.17Å; R23-D171 PolarHBondContact NH1-OD1 2.89Å; R23-D171 IonicContact NH2-OD1 3.43Å; R23-D171 PolarHBondContact NH2-OD1 2.95Å
24P94.4Very high74.7Confident77 Ų7749.5 Ų49.550%0.528%0.281SS..G310 helixtrans-63.8-20.4178.5-2436.7000115.5P22 N27 P38P22-P24 WeakPolarHBondContact O-CD 3.42Å; P24-N27 PolarHBondContact O-ND2 3.21Å; P24-P38 HydrophobicContact CB-CB 3.92Å; P24-P38 HydrophobicContact CB-CG 4.07Å; P24-P38 HydrophobicContact CG-CB 4.04Å; P24-P38 HydrophobicContact CG-CG 4.35Å
25C94.4Very high78Confident4 Ų446.3 Ų46.33%0.02727%0.265CS..G310 helixtrans-93.5-12177.9-52.60000113.5F21 P22 R23 N27 C36 P38 F86F21-C25 HydrophobicContact CB-CB 4.41Å; P22-C25 WeakPolarHBondContact O-CA 3.27Å; P22-C25 WeakPolarHBondContact O-CB 3.47Å; P22-C25 PolarHBondContact O-N 3.24Å; R23-C25 PolarHBondContact O-N 3.43Å; C25-N27 PolarHBondContact O-N 3.37Å; C25-C36 HydrophobicContact CB-CB 3.65Å; C25-C36 WeakPolarHBondContact CB-SG 3.44Å; C25-C36 WeakPolarHBondContact SG-CA 3.34Å; C25-C36 WeakPolarHBondContact SG-CB 3.42Å; C25-C36 CovalentContact SG-SG 2.03Å; C25-C36 PolarHBondContact SG-SG 3.29Å; C25-P38 WeakPolarHBondContact SG-CG 3.32Å; C25-F86 HydrophobicContact CB-CE1 4.2Å; C25-F86 HydrophobicContact CB-CZ 3.97Å
26A93.9Very high81.2Confident3 Ų342.9 Ų42.93%0.02523%0.229CC..SBendtrans-77.642.9-17000000114.7S19 P22 R23 F169S19-A26 WeakPolarHBondContact OG-CA 3.46Å; S19-A26 WeakPolarHBondContact OG-CB 3.35Å; P22-A26 PolarHBondContact O-N 3.5Å; R23-A26 WeakPolarHBondContact O-CB 3.28Å; R23-A26 PolarHBondContact O-N 2.82Å; R23-A26 VanDerWaalsContact O-N 3.15Å; A26-F169 HydrophobicContact CB-CD2 4.22Å; A26-F169 VanDerWaalsContact O-CD2 3.28Å; A26-F169 WeakPolarHBondContact O-CD2 3.33Å
27N94.1Very high84.5Confident56 Ų5638 Ų3830%0.29920%0.2SC..SBendtrans-147.8171.2-169.556.759.9000111.8P24 C25 E29 G30 L31P24-N27 PolarHBondContact O-ND2 3.21Å; C25-N27 PolarHBondContact O-N 3.37Å; N27-E29 PolarHBondContact O-N 2.9Å; N27-E29 WeakPolarHBondContact OD1-CA 3.38Å; N27-E29 VanDerWaalsContact OD1-CB 3.31Å; N27-E29 WeakPolarHBondContact OD1-CB 3.31Å; N27-E29 PolarHBondContact OD1-N 3.29Å; N27-E29 VanDerWaalsContact OD1-N 3.09Å; N27-G30 PolarHBondContact O-N 2.88Å; N27-G30 PolarHBondContact OD1-N 3.48Å; N27-L31 WeakPolarHBondContact O-CG 3.49Å; N27-L31 PolarHBondContact O-N 3.42Å
28S94.6Very high87.6Confident44 Ų4434.2 Ų34.231%0.30817%0.174SC..Hα-helixtrans-56.5-34.9178.7-61.40000113.2R32 G164 P167S28-R32 WeakPolarHBondContact O-CB 3.44Å; S28-R32 PolarHBondContact O-N 3.43Å; S28-G164 WeakPolarHBondContact CA-O 3.35Å; S28-G164 WeakPolarHBondContact CB-O 3.04Å; S28-G164 PolarHBondContact OG-O 3.2Å; S28-P167 VanDerWaalsContact OG-CD 3.31Å; S28-P167 WeakPolarHBondContact OG-CD 3.28Å; S28-P167 WeakPolarHBondContact OG-CG 3.36Å
29E94.3Very high90.5Very high92 Ų9237.9 Ų37.943%0.4320%0.196SC..Hα-helixtrans-65.7-49.3178.7-169.162.9-146.500111.2N27 L31 R32 T33N27-E29 PolarHBondContact O-N 2.9Å; N27-E29 WeakPolarHBondContact OD1-CA 3.38Å; N27-E29 VanDerWaalsContact OD1-CB 3.31Å; N27-E29 WeakPolarHBondContact OD1-CB 3.31Å; N27-E29 PolarHBondContact OD1-N 3.29Å; N27-E29 VanDerWaalsContact OD1-N 3.09Å; E29-L31 VanDerWaalsContact C-N 3.34Å; E29-L31 PolarHBondContact O-N 2.84Å; E29-R32 PolarHBondContact O-N 2.81Å; E29-R32 IonicContact OE1-CZ 2.66Å; E29-R32 IonicContact OE1-NH2 2.91Å; E29-R32 PolarHBondContact OE1-NH2 3.24Å; E29-R32 IonicContact OE2-CZ 3.35Å; E29-R32 IonicContact OE2-NH1 2.69Å; E29-R32 PolarHBondContact OE2-NH1 2.87Å; E29-R32 IonicContact OE2-NH2 3.26Å; E29-R32 PolarHBondContact OE2-NH2 3.35Å; E29-T33 HydrophobicContact CG-CG2 4.32Å; E29-T33 WeakPolarHBondContact O-CB 3.45Å; E29-T33 WeakPolarHBondContact O-CG2 3.32Å; E29-T33 PolarHBondContact O-N 2.9Å; E29-T33 PolarHBondContact O-OG1 3.33Å; E29-T33 WeakPolarHBondContact OE1-CG2 3.34Å
30G93.9Very high93.5Very high4 Ų440.1 Ų40.14%0.04120%0.204CC..Hα-helixtrans-59.8-43.8177.500000111.9N27 T33 K34 E35 F86N27-G30 PolarHBondContact O-N 2.88Å; N27-G30 PolarHBondContact OD1-N 3.48Å; G30-T33 PolarHBondContact O-OG1 2.87Å; G30-K34 WeakPolarHBondContact O-CA 3.34Å; G30-K34 PolarHBondContact O-N 3.46Å; G30-E35 PolarHBondContact O-N 3.48Å; G30-F86 WeakPolarHBondContact O-CE1 3.37Å
31L94.6Very high94.9Very high0 Ų049 Ų490%025%0.246CC..Hα-helixtrans-68.8-35.5178-69.5178.9000113.7N27 E29 F85 M160 P167 F169N27-L31 WeakPolarHBondContact O-CG 3.49Å; N27-L31 PolarHBondContact O-N 3.42Å; E29-L31 VanDerWaalsContact C-N 3.34Å; E29-L31 PolarHBondContact O-N 2.84Å; L31-F85 HydrophobicContact CD2-CD1 4.04Å; L31-M160 HydrophobicContact CD1-CB 4.24Å; L31-M160 HydrophobicContact CD1-SD 3.66Å; L31-M160 HydrophobicContact CD2-SD 4.38Å; L31-P167 HydrophobicContact CD1-CB 4.1Å; L31-F169 HydrophobicContact CD1-CE2 3.87Å; L31-F169 HydrophobicContact CD1-CZ 4.03Å; L31-F169 HydrophobicContact CD2-CZ 4.14Å; L31-F169 HydrophobicContact CG-CE2 4.31Å; L31-F169 HydrophobicContact CG-CZ 4.31Å
32R95.3Very high95.2Very high136 Ų13651.4 Ų51.451%0.51327%0.271SS..Hα-helixtrans-72.8-47.7178.7-171.7177.871.7-143.73.1111.8S28 E29 K34 N163S28-R32 WeakPolarHBondContact O-CB 3.44Å; S28-R32 PolarHBondContact O-N 3.43Å; E29-R32 PolarHBondContact O-N 2.81Å; E29-R32 IonicContact OE1-CZ 2.66Å; E29-R32 IonicContact OE1-NH2 2.91Å; E29-R32 PolarHBondContact OE1-NH2 3.24Å; E29-R32 IonicContact OE2-CZ 3.35Å; E29-R32 IonicContact OE2-NH1 2.69Å; E29-R32 PolarHBondContact OE2-NH1 2.87Å; E29-R32 IonicContact OE2-NH2 3.26Å; E29-R32 PolarHBondContact OE2-NH2 3.35Å; R32-K34 VanDerWaalsContact C-N 3.27Å; R32-N163 WeakPolarHBondContact CA-O 3.35Å; R32-N163 VanDerWaalsContact CB-O 3.25Å; R32-N163 WeakPolarHBondContact CB-O 3.33Å; R32-N163 HydrophobicContact CG-CB 4.25Å
33T95.5Very high95.3Very high63 Ų6353 Ų5339%0.38728%0.28SS..Hα-helixtrans-76.5-18.918058.60000112.3E29 G30 E35E29-T33 HydrophobicContact CG-CG2 4.32Å; E29-T33 WeakPolarHBondContact O-CB 3.45Å; E29-T33 WeakPolarHBondContact O-CG2 3.32Å; E29-T33 PolarHBondContact O-N 2.9Å; E29-T33 PolarHBondContact O-OG1 3.33Å; E29-T33 WeakPolarHBondContact OE1-CG2 3.34Å; G30-T33 PolarHBondContact O-OG1 2.87Å; T33-E35 PolarHBondContact O-N 2.88Å; T33-E35 PolarHBondContact OG1-N 3.48Å
34K96.3Very high95.5Very high76 Ų7653.3 Ų53.333%0.3330%0.298SS..THydrogen-bonded Turntrans55.826.8-170.3-59.8-167.5171.8-1650112.5G30 R32 F86 N87 R88G30-K34 WeakPolarHBondContact O-CA 3.34Å; G30-K34 PolarHBondContact O-N 3.46Å; R32-K34 VanDerWaalsContact C-N 3.27Å; K34-F86 CarbonylContact O-C 3.43Å; K34-F86 WeakPolarHBondContact O-CA 3.11Å; K34-N87 HydrophobicContact CB-CB 4.45Å; K34-N87 WeakPolarHBondContact CB-OD1 3.05Å; K34-N87 PolarHBondContact O-N 2.95Å; K34-N87 PolarHBondContact O-OD1 3.25Å; K34-R88 PolarHBondContact O-N 2.95Å; K34-R88 VanDerWaalsContact O-N 3.15Å
35E97.1Very high95.6Very high74 Ų7450.4 Ų50.435%0.34628%0.279SS..EExtended strand (participates in β ladder)trans-111124.2177.7-174.8168.8108.300111G30 T33 C37 C56 R88G30-E35 PolarHBondContact O-N 3.48Å; T33-E35 PolarHBondContact O-N 2.88Å; T33-E35 PolarHBondContact OG1-N 3.48Å; E35-C37 HydrophobicContact CG-CB 3.95Å; E35-C56 PolarHBondContact OE2-SG 2.9Å; E35-C56 VanDerWaalsContact OE2-SG 3.38Å; E35-R88 HydrophobicContact CB-CB 4.17Å; E35-R88 HydrophobicContact CG-CB 3.89Å; E35-R88 WeakPolarHBondContact OE2-CD 3.39Å; E35-R88 IonicContact OE2-CZ 2.69Å; E35-R88 IonicContact OE2-NE 2.62Å; E35-R88 PolarHBondContact OE2-NE 3.03Å; E35-R88 IonicContact OE2-NH2 3.69Å
36C97.3Very high95.8Very high5 Ų552.1 Ų52.13%0.03429%0.294CS..EExtended strand (participates in β ladder)trans-118.880.5169.1-178.70000109.6C25 F86 R88 T89C25-C36 HydrophobicContact CB-CB 3.65Å; C25-C36 WeakPolarHBondContact CB-SG 3.44Å; C25-C36 WeakPolarHBondContact SG-CA 3.34Å; C25-C36 WeakPolarHBondContact SG-CB 3.42Å; C25-C36 CovalentContact SG-SG 2.03Å; C25-C36 PolarHBondContact SG-SG 3.29Å; C36-F86 HydrophobicContact CB-CB 4.41Å; C36-F86 HydrophobicContact CB-CD1 3.51Å; C36-F86 HydrophobicContact CB-CD2 4.12Å; C36-F86 HydrophobicContact CB-CE1 3.71Å; C36-F86 HydrophobicContact CB-CE2 4.34Å; C36-F86 HydrophobicContact CB-CG 3.73Å; C36-F86 HydrophobicContact CB-CZ 4.14Å; C36-R88 PolarHBondContact N-O 3.17Å; C36-T89 HydrophobicContact CB-CG2 4.47Å; C36-T89 WeakPolarHBondContact O-CA 3.42Å
37C97.8Very high96Very high15 Ų1552 Ų5210%0.10129%0.293CS..  trans-126.169.7179-68.70000111.7E35 A46 C56E35-C37 HydrophobicContact CG-CB 3.95Å; C37-A46 HydrophobicContact CB-CB 4.49Å; C37-C56 HydrophobicContact CB-CB 3.57Å; C37-C56 WeakPolarHBondContact CB-SG 3.43Å; C37-C56 WeakPolarHBondContact SG-CA 3.39Å; C37-C56 WeakPolarHBondContact SG-CB 3.43Å; C37-C56 CovalentContact SG-SG 2.03Å; C37-C56 PolarHBondContact SG-SG 3.12Å
38P96.8Very high96.2Very high9 Ų949.3 Ų49.36%0.05828%0.278CS..PPolyproline II helixtrans-61.7152.3-174.9-24.938000112.8P22 P24 C25 C47 F99 N100P22-P38 HydrophobicContact CB-CG 4.26Å; P24-P38 HydrophobicContact CB-CB 3.92Å; P24-P38 HydrophobicContact CB-CG 4.07Å; P24-P38 HydrophobicContact CG-CB 4.04Å; P24-P38 HydrophobicContact CG-CG 4.35Å; C25-P38 WeakPolarHBondContact SG-CG 3.32Å; P38-C47 PolarHBondContact O-N 3.24Å; P38-F99 HydrophobicContact CB-CD2 4.13Å; P38-F99 HydrophobicContact CB-CE2 4.02Å; P38-F99 HydrophobicContact CG-CD2 3.8Å; P38-F99 HydrophobicContact CG-CE2 4.08Å; P38-N100 HydrophobicContact CB-CB 4.14Å
39V97.1Very high96.3Very high82 Ų8248.9 Ų48.950%0.49728%0.278SS..EExtended strand (participates in β ladder)trans-67.2137.8172.9172.70000109.8G44 S45 N100V39-G44 WeakPolarHBondContact CG1-O 3.46Å; V39-S45 WeakPolarHBondContact CA-O 3.37Å; V39-N100 PolarHBondContact O-ND2 2.78Å
40W96.5Very high96.5Very high48 Ų4851.3 Ų51.318%0.18229%0.293CS..EExtended strand (participates in β ladder)trans-89.1123.5165.6178.855.8000109.6G42 D43 G44 S45 S51 R53 G102W40-G42 PolarHBondContact O-N 2.84Å; W40-G42 VanDerWaalsContact O-N 3.11Å; W40-D43 HydrophobicContact CE3-CB 4.01Å; W40-D43 HydrophobicContact CZ3-CB 3.93Å; W40-D43 PolarHBondContact O-N 3.31Å; W40-G44 PolarHBondContact O-N 3.49Å; W40-S45 PolarHBondContact N-O 3.31Å; W40-S51 WeakPolarHBondContact CZ3-OG 3.46Å; W40-R53 VanDerWaalsContact CZ2-CZ 3.41Å; W40-G102 VanDerWaalsContact NE1-CA 3.26Å
41E94.3Very high96.7Very high188 Ų18853.9 Ų53.988%0.87931%0.31SS*.THydrogen-bonded Turntrans-60-25.8-175.6-64.2-171.6159.700113.6D43E41-D43 VanDerWaalsContact C-N 3.3Å; E41-D43 PolarHBondContact O-N 2.89Å
42G94.1Very high96.8Very high53 Ų5355.5 Ų55.555%0.54633%0.327SS..THydrogen-bonded Turntrans-67.5-25.7-176.300000114.7W40W40-G42 PolarHBondContact O-N 2.84Å; W40-G42 VanDerWaalsContact O-N 3.11Å
43D96.3Very high96.9Very high36 Ų3649.9 Ų49.919%0.19331%0.306CS..THydrogen-bonded Turntrans-135-0.4175.870.514.1000115.1W40 E41 S45 G48 L50 S51W40-D43 HydrophobicContact CE3-CB 4.01Å; W40-D43 HydrophobicContact CZ3-CB 3.93Å; W40-D43 PolarHBondContact O-N 3.31Å; E41-D43 VanDerWaalsContact C-N 3.3Å; E41-D43 PolarHBondContact O-N 2.89Å; D43-S45 PolarHBondContact O-N 2.95Å; D43-S45 WeakPolarHBondContact OD1-CB 3.49Å; D43-S45 PolarHBondContact OD1-N 2.94Å; D43-S45 PolarHBondContact OD1-OG 3.29Å; D43-S45 PolarHBondContact OD2-OG 3.47Å; D43-G48 WeakPolarHBondContact OD2-CA 3.49Å; D43-L50 HydrophobicContact CB-CB 4.23Å; D43-L50 PolarHBondContact OD2-N 3.29Å; D43-S51 VanDerWaalsContact CB-OG 3.29Å; D43-S51 WeakPolarHBondContact CB-OG 3.49Å; D43-S51 WeakPolarHBondContact OD2-CB 2.98Å; D43-S51 PolarHBondContact OD2-N 2.96Å; D43-S51 PolarHBondContact OD2-OG 2.95Å
44G96.8Very high97Very high54 Ų5446.9 Ų46.956%0.55729%0.287SS*.THydrogen-bonded Turntrans729.1177.600000114.6V39 W40V39-G44 WeakPolarHBondContact CG1-O 3.46Å; W40-G44 PolarHBondContact O-N 3.49Å
45S97.9Very high97.1Very high16 Ų1648.1 Ų48.111%0.11229%0.293CS..EExtended strand (participates in β ladder)trans-105.3151.4179.371.60000113.1V39 W40 D43 C47 G48 A49 L50V39-S45 WeakPolarHBondContact CA-O 3.37Å; W40-S45 PolarHBondContact N-O 3.31Å; D43-S45 PolarHBondContact O-N 2.95Å; D43-S45 WeakPolarHBondContact OD1-CB 3.49Å; D43-S45 PolarHBondContact OD1-N 2.94Å; D43-S45 PolarHBondContact OD1-OG 3.29Å; D43-S45 PolarHBondContact OD2-OG 3.47Å; S45-C47 PolarHBondContact O-N 2.96Å; S45-G48 PolarHBondContact O-N 2.91Å; S45-G48 WeakPolarHBondContact OG-CA 3.48Å; S45-A49 PolarHBondContact OG-N 3.48Å; S45-L50 PolarHBondContact OG-N 2.75Å
46A97.9Very high97.1Very high40 Ų4045.9 Ų45.933%0.33129%0.285SS..EExtended strand (participates in β ladder)trans-57.6128.7173.400000110.2C37 G48 A49C37-A46 HydrophobicContact CB-CB 4.49Å; A46-G48 PolarHBondContact O-N 3.39Å; A46-G48 VanDerWaalsContact O-N 3.08Å; A46-A49 WeakPolarHBondContact O-CB 3.4Å; A46-A49 PolarHBondContact O-N 3.26Å
47C97.9Very high97.1Very high0 Ų047.1 Ų47.10%029%0.292CS..THydrogen-bonded Turntrans57.818.3-179.1-45.50000115.2P38 S45 A49 G54 C56 C90 N100 C101P38-C47 PolarHBondContact O-N 3.24Å; S45-C47 PolarHBondContact O-N 2.96Å; C47-A49 VanDerWaalsContact C-N 3.31Å; C47-A49 PolarHBondContact O-N 3.49Å; C47-G54 CarbonylContact O-C 3.57Å; C47-G54 WeakPolarHBondContact O-CA 3.24Å; C47-G54 PolarHBondContact O-N 2.98Å; C47-G54 VanDerWaalsContact O-N 3.17Å; C47-C56 PolarHBondContact SG-N 3.38Å; C47-C90 WeakPolarHBondContact CA-SG 3.19Å; C47-C90 HydrophobicContact CB-CB 3.68Å; C47-C90 WeakPolarHBondContact CB-SG 3.48Å; C47-C90 WeakPolarHBondContact SG-CA 3.5Å; C47-C90 WeakPolarHBondContact SG-CB 3.31Å; C47-C90 CovalentContact SG-SG 2.03Å; C47-C90 PolarHBondContact SG-SG 3.39Å; C47-N100 CarbonylContact C-O 3.6Å; C47-N100 WeakPolarHBondContact CA-O 3.23Å; C47-C101 WeakPolarHBondContact O-CB 3.45Å
48G97.7Very high97.2Very high0 Ų050.9 Ų50.90%031%0.309CS..THydrogen-bonded Turntrans63.333.7-176.500000113.9D43 S45 A46 L50 S51 G52 R53D43-G48 WeakPolarHBondContact OD2-CA 3.49Å; S45-G48 PolarHBondContact O-N 2.91Å; S45-G48 WeakPolarHBondContact OG-CA 3.48Å; A46-G48 PolarHBondContact O-N 3.39Å; A46-G48 VanDerWaalsContact O-N 3.08Å; G48-L50 PolarHBondContact O-N 2.98Å; G48-S51 PolarHBondContact O-N 3.48Å; G48-G52 PolarHBondContact O-N 3.41Å; G48-R53 WeakPolarHBondContact O-CB 3.42Å; G48-R53 PolarHBondContact O-N 3.41Å
49A98.1Very high97.2Very high36 Ų3651.1 Ų51.130%0.29831%0.31SS..G310 helixtrans-60.3-37.2-177.400000114.1S45 A46 C47 S51 G52 G54 F55S45-A49 PolarHBondContact OG-N 3.48Å; A46-A49 WeakPolarHBondContact O-CB 3.4Å; A46-A49 PolarHBondContact O-N 3.26Å; C47-A49 VanDerWaalsContact C-N 3.31Å; C47-A49 PolarHBondContact O-N 3.49Å; A49-S51 PolarHBondContact O-N 2.86Å; A49-G52 PolarHBondContact O-N 2.95Å; A49-G54 WeakPolarHBondContact CA-O 3.36Å; A49-G54 PolarHBondContact N-O 3.48Å; A49-F55 HydrophobicContact CB-CD1 3.91Å; A49-F55 HydrophobicContact CB-CE1 4.09Å
50L97.9Very high97.1Very high142 Ų14253.1 Ų53.174%0.74332%0.317SS*.G310 helixtrans-65.7-29179-71.6176.6000112.3D43 S45 G48D43-L50 HydrophobicContact CB-CB 4.23Å; D43-L50 PolarHBondContact OD2-N 3.29Å; S45-L50 PolarHBondContact OG-N 2.75Å; G48-L50 PolarHBondContact O-N 2.98Å
51S96.9Very high97.1Very high59 Ų5952 Ų5241%0.41332%0.316SS..G310 helixtrans-92.83.3174.6-56.10000113.6W40 D43 G48 A49 R53W40-S51 WeakPolarHBondContact CZ3-OG 3.46Å; D43-S51 VanDerWaalsContact CB-OG 3.29Å; D43-S51 WeakPolarHBondContact CB-OG 3.49Å; D43-S51 WeakPolarHBondContact OD2-CB 2.98Å; D43-S51 PolarHBondContact OD2-N 2.96Å; D43-S51 PolarHBondContact OD2-OG 2.95Å; G48-S51 PolarHBondContact O-N 3.48Å; A49-S51 PolarHBondContact O-N 2.86Å; S51-R53 PolarHBondContact O-N 2.89Å
52G96.9Very high97.1Very high34 Ų3445 Ų4535%0.35129%0.288SS..THydrogen-bonded Turntrans66.222.7-177.500000114.1G48 A49G48-G52 PolarHBondContact O-N 3.41Å; A49-G52 PolarHBondContact O-N 2.95Å
53R97.8Very high97.2Very high17 Ų1748.8 Ų48.86%0.06430%0.295CS..SBendtrans-76.2-29.4180-71.3177.9162.9-98.4-0.3113.4W40 G48 S51 C92 A93 Y96 C101 G102 G111W40-R53 VanDerWaalsContact CZ2-CZ 3.41Å; G48-R53 WeakPolarHBondContact O-CB 3.42Å; G48-R53 PolarHBondContact O-N 3.41Å; S51-R53 PolarHBondContact O-N 2.89Å; R53-C92 CarbonylContact O-C 3.53Å; R53-C92 WeakPolarHBondContact O-CA 3.35Å; R53-A93 PolarHBondContact O-N 3.24Å; R53-Y96 HydrophobicContact CB-CD1 4.47Å; R53-Y96 HydrophobicContact CB-CD2 4Å; R53-Y96 HydrophobicContact CB-CE2 4.33Å; R53-Y96 HydrophobicContact CB-CG 4.08Å; R53-Y96 HydrophobicContact CG-CD1 4.01Å; R53-Y96 HydrophobicContact CG-CD2 4.02Å; R53-Y96 HydrophobicContact CG-CE1 3.93Å; R53-Y96 HydrophobicContact CG-CE2 3.93Å; R53-Y96 HydrophobicContact CG-CG 4.07Å; R53-C101 HydrophobicContact CB-CB 4.03Å; R53-C101 WeakPolarHBondContact CD-O 3.4Å; R53-C101 PolarHBondContact NH1-O 3.5Å; R53-C101 VanDerWaalsContact NH1-O 3.17Å; R53-G102 PolarHBondContact NH1-O 3.43Å; R53-G111 PolarHBondContact NH2-O 3.42Å
54G97.7Very high97.2Very high0 Ų050.6 Ų50.60%030%0.302CS..EExtended strand (participates in β ladder)trans176.7175.8-176.700000111.4C47 A49 R91C47-G54 CarbonylContact O-C 3.57Å; C47-G54 WeakPolarHBondContact O-CA 3.24Å; C47-G54 PolarHBondContact O-N 2.98Å; C47-G54 VanDerWaalsContact O-N 3.17Å; A49-G54 WeakPolarHBondContact CA-O 3.36Å; A49-G54 PolarHBondContact N-O 3.48Å; G54-R91 WeakPolarHBondContact CA-O 3.22Å
55F97.9Very high97.2Very high103 Ų10351.2 Ų51.245%0.45230%0.297SS..EExtended strand (participates in β ladder)trans-141.6147.4-178.1-57.5-83.3000109.9A49 T57 R91A49-F55 HydrophobicContact CB-CD1 3.91Å; A49-F55 HydrophobicContact CB-CE1 4.09Å; F55-T57 HydrophobicContact CB-CG2 4.21Å; F55-T57 PolarHBondContact O-N 2.98Å; F55-R91 PolarHBondContact N-O 3.26Å; F55-R91 PolarHBondContact O-N 3.48Å
56C98Very high97.1Very high27 Ų2753.5 Ų53.518%0.18231%0.308CS..EExtended strand (participates in β ladder)trans-73.4118.4170.8-172.50000109.6E35 C37 C47 R88E35-C56 PolarHBondContact OE2-SG 2.9Å; E35-C56 VanDerWaalsContact OE2-SG 3.38Å; C37-C56 HydrophobicContact CB-CB 3.57Å; C37-C56 WeakPolarHBondContact CB-SG 3.43Å; C37-C56 WeakPolarHBondContact SG-CA 3.39Å; C37-C56 WeakPolarHBondContact SG-CB 3.43Å; C37-C56 CovalentContact SG-SG 2.03Å; C37-C56 PolarHBondContact SG-SG 3.12Å; C47-C56 PolarHBondContact SG-N 3.38Å; C56-R88 PolarHBondContact O-NH2 3.33Å
57T97.7Very high96.9Very high30 Ų3051.9 Ų51.918%0.18430%0.295CS..EExtended strand (participates in β ladder)trans-135.5155.2-174.1600000112.1F55 R88 T89 R91F55-T57 HydrophobicContact CB-CG2 4.21Å; F55-T57 PolarHBondContact O-N 2.98Å; T57-R88 VanDerWaalsContact O-CA 3.3Å; T57-R88 WeakPolarHBondContact O-CA 3.32Å; T57-T89 PolarHBondContact N-O 3Å; T57-T89 PolarHBondContact O-N 3.47Å; T57-R91 HydrophobicContact CG2-CB 4.36Å; T57-R91 WeakPolarHBondContact OG1-CB 3.24Å
58E98.1Very high96.8Very high95 Ų9557.7 Ų57.744%0.44433%0.332SS..EExtended strand (participates in β ladder)trans-56.5140.3168.9-64.1-60.914100111.2L60 N87 R88E58-L60 PolarHBondContact O-N 3.31Å; E58-N87 CarbonylContact C-O 3.4Å; E58-N87 WeakPolarHBondContact CA-O 3.31Å; E58-R88 WeakPolarHBondContact OE1-CD 3.41Å; E58-R88 WeakPolarHBondContact OE1-CG 3.44Å; E58-R88 IonicContact OE1-CZ 2.82Å; E58-R88 IonicContact OE1-NE 3.45Å; E58-R88 IonicContact OE1-NH1 2.83Å; E58-R88 PolarHBondContact OE1-NH1 2.9Å
59V97.6Very high96.6Very high13 Ų1359.4 Ų59.48%0.07934%0.34CS..  trans-85112.4176.2-179.10000109V61 P82 L83 N87 T89 Y428 L435V59-V61 HydrophobicContact CG1-CG1 4.12Å; V59-P82 HydrophobicContact CG1-CG 4.3Å; V59-P82 HydrophobicContact CG2-CG 4.45Å; V59-L83 HydrophobicContact CB-CD2 4.09Å; V59-L83 HydrophobicContact CG1-CD2 4.29Å; V59-N87 PolarHBondContact N-O 2.92Å; V59-T89 HydrophobicContact CG2-CG2 3.75Å; V59-T89 WeakPolarHBondContact CG2-OG1 3.38Å; V59-Y428 HydrophobicContact CG1-CD2 4.33Å; V59-Y428 HydrophobicContact CG1-CE2 3.67Å; V59-L435 HydrophobicContact CB-CD1 4.41Å; V59-L435 HydrophobicContact CG1-CD1 3.58Å; V59-L435 HydrophobicContact CG2-CD1 3.89Å
60L95.9Very high96.5Very high125 Ų12558.6 Ų58.665%0.65433%0.33SS*.  trans-93.8110.3175-55.8179.6000109.6E58 Y428 R437E58-L60 PolarHBondContact O-N 3.31Å; L60-Y428 VanDerWaalsContact O-CE2 3.27Å; L60-Y428 WeakPolarHBondContact O-CE2 3.5Å; L60-Y428 PolarHBondContact O-OH 3.4Å; L60-R437 PolarHBondContact O-NH2 2.91Å
61V96.1Very high96.3Very high24 Ų2455.8 Ų55.815%0.14532%0.32CS..  trans-94.3152.4174.5-56.40000110.3V59 R80 L83 Y428V59-V61 HydrophobicContact CG1-CG1 4.12Å; V61-R80 HydrophobicContact CG2-CB 4.31Å; V61-L83 HydrophobicContact CB-CD1 4.37Å; V61-L83 HydrophobicContact CG1-CD1 3.78Å; V61-L83 HydrophobicContact CG1-CD2 4.32Å; V61-L83 HydrophobicContact CG1-CG 3.8Å; V61-L83 HydrophobicContact CG2-CD1 3.63Å; V61-Y428 HydrophobicContact CG1-CD2 4.16Å; V61-Y428 HydrophobicContact CG1-CE2 4.21Å
62S94.2Very high96.3Very high42 Ų4255.5 Ų55.529%0.29431%0.312SS..  trans-66.7142.4176.4-170.60000111.1E64S62-E64 WeakPolarHBondContact OG-CB 3.5Å; S62-E64 WeakPolarHBondContact OG-CG 3.5Å; S62-E64 PolarHBondContact OG-N 2.84Å
63D95.1Very high96.1Very high132 Ų13259.8 Ų59.871%0.70633%0.332SS*.  trans-1028.3170.8-65.2-48.4000112.1R80D63-R80 IonicContact OD1-CZ 2.78Å; D63-R80 IonicContact OD1-NH1 3.99Å; D63-R80 IonicContact OD1-NH2 3.91Å; D63-R80 PolarHBondContact OD1-NH2 3.26Å
64E97Very high95.9Very high73 Ų7362.4 Ų62.434%0.34136%0.364SS..PPolyproline II helixtrans-60.8137.8174.1-67.1-68.917600110.9S62 Q416 A417S62-E64 WeakPolarHBondContact OG-CB 3.5Å; S62-E64 WeakPolarHBondContact OG-CG 3.5Å; S62-E64 PolarHBondContact OG-N 2.84Å; E64-Q416 HydrophobicContact CG-CG 4.38Å; E64-Q416 PolarHBondContact OE1-NE2 3Å; E64-A417 HydrophobicContact CB-CB 4.02Å
65P96.5Very high95.8Very high67 Ų6766.1 Ų66.144%0.43538%0.383SS..PPolyproline II helixtrans-65144.2-176.326.7-34.3000111.8A417 N418 N424P65-A417 HydrophobicContact CG-CB 4.23Å; P65-N418 WeakPolarHBondContact CG-OD1 3.5Å; P65-N418 WeakPolarHBondContact O-CA 3.43Å; P65-N418 PolarHBondContact O-N 2.79Å; P65-N424 PolarHBondContact O-ND2 3.16Å
66N95.9Very high95.7Very high64 Ų6461.6 Ų61.634%0.34236%0.364SS..PPolyproline II helixtrans-86.1162.1169.1-56.7-52.1000110.2I421 N424N66-I421 HydrophobicContact CB-CB 4.17Å; N66-N424 PolarHBondContact OD1-ND2 3.02Å
67G94.9Very high95.7Very high6 Ų661.6 Ų61.66%0.06236%0.362CS..PPolyproline II helixtrans-64.3165.1171.300000112.9Q69 N418 A419G67-Q69 VanDerWaalsContact CA-OE1 3.23Å; G67-Q69 PolarHBondContact O-N 2.84Å; G67-N418 VanDerWaalsContact CA-O 3.24Å; G67-N418 WeakPolarHBondContact CA-O 3.31Å; G67-N418 PolarHBondContact N-O 3.21Å; G67-A419 PolarHBondContact N-O 2.75Å
68P94.3Very high95.7Very high122 Ų12260.2 Ų60.279%0.79235%0.353SS*.THydrogen-bonded Turntrans-75.2-2-172.732.9-37.8000114.6Y70P68-Y70 PolarHBondContact O-N 3.38Å
69Q93.5Very high95.6Very high36 Ų3656.9 Ų56.917%0.16834%0.337CS..THydrogen-bonded Turntrans-65.6-26-172.6-6384.8-9.800113.1G67 W198 P420G67-Q69 VanDerWaalsContact CA-OE1 3.23Å; G67-Q69 PolarHBondContact O-N 2.84Å; Q69-W198 WeakPolarHBondContact O-CZ2 3.41Å; Q69-P420 HydrophobicContact CG-CG 4.47Å
70Y95.9Very high95.6Very high19 Ų1962.3 Ų62.38%0.07536%0.356CS..  trans-114.7101.6178.7-175.7-109.1000110.7P68 H72 I75 D76 E79 T189 W198 I201 I421P68-Y70 PolarHBondContact O-N 3.38Å; Y70-H72 VanDerWaalsContact C-N 3.27Å; Y70-H72 HydrophobicContact CD1-CB 4.46Å; Y70-H72 WeakPolarHBondContact CD1-O 3.26Å; Y70-H72 HydrophobicContact CE1-CB 3.83Å; Y70-H72 WeakPolarHBondContact CE1-O 3.4Å; Y70-H72 HydrophobicContact CE2-CB 4.06Å; Y70-H72 AromaticContact CE2-CD2 3.86Å; Y70-H72 PolarHBondContact O-N 3.41Å; Y70-I75 VanDerWaalsContact OH-CG1 3.31Å; Y70-I75 WeakPolarHBondContact OH-CG1 3.42Å; Y70-D76 WeakPolarHBondContact OH-CB 3.35Å; Y70-E79 HydrophobicContact CE1-CG 4.18Å; Y70-E79 PolarHBondContact OH-OE1 3.47Å; Y70-T189 HydrophobicContact CE2-CG2 4.37Å; Y70-W198 AromaticContact CD2-CD1 3.7Å; Y70-W198 HydrophobicContact CD2-CG 4.42Å; Y70-W198 AromaticContact CD2-NE1 3.86Å; Y70-W198 HydrophobicContact CE2-CG 4.47Å; Y70-I201 HydrophobicContact CD2-CB 4.37Å; Y70-I201 HydrophobicContact CD2-CD1 3.73Å; Y70-I201 HydrophobicContact CD2-CG1 4.39Å; Y70-I201 HydrophobicContact CE2-CD1 3.6Å; Y70-I201 HydrophobicContact CG-CD1 4.34Å; Y70-I421 HydrophobicContact CD1-CD1 3.79Å; Y70-I421 HydrophobicContact CD1-CG2 4.25Å; Y70-I421 HydrophobicContact CE1-CD1 4.11Å; Y70-I421 HydrophobicContact CG-CG2 4.01Å
71P95.3Very high95.6Very high83 Ų8356.4 Ų56.454%0.53933%0.326SS..  trans-87.813.5-172.236-37.2000113.9W198P71-W198 HydrophobicContact CG-CE3 4.46Å; P71-W198 HydrophobicContact CG-CH2 3.85Å; P71-W198 HydrophobicContact CG-CZ2 4.11Å; P71-W198 HydrophobicContact CG-CZ3 4.04Å
72H95.4Very high95.7Very high53 Ų5355.2 Ų55.225%0.24532%0.319CS..  trans-111.6160.7-175.3-54.5-77.3000112.1Y70 I75 W198Y70-H72 VanDerWaalsContact C-N 3.27Å; Y70-H72 HydrophobicContact CD1-CB 4.46Å; Y70-H72 WeakPolarHBondContact CD1-O 3.26Å; Y70-H72 HydrophobicContact CE1-CB 3.83Å; Y70-H72 WeakPolarHBondContact CE1-O 3.4Å; Y70-H72 HydrophobicContact CE2-CB 4.06Å; Y70-H72 AromaticContact CE2-CD2 3.86Å; Y70-H72 PolarHBondContact O-N 3.41Å; H72-I75 HydrophobicContact CB-CD1 3.34Å; H72-I75 HydrophobicContact CB-CG1 3.73Å; H72-W198 AromaticContact NE2-CD2 3.73Å; H72-W198 AromaticContact NE2-CE3 3.44Å; H72-W198 AromaticContact NE2-CG 3.99Å
73T93.4Very high95.8Very high125 Ų12555.6 Ų55.677%0.76732%0.317SS*.  trans-150.4134.5178.1-56.30000110.1I75 E79T73-I75 VanDerWaalsContact C-N 3.34Å; T73-E79 WeakPolarHBondContact CA-OE2 3.41Å
74G93.4Very high95.8Very high71 Ų7150.5 Ų50.573%0.73229%0.293SS*.SBendtrans72.922.8176.500000114.2E79G74-E79 VanDerWaalsContact N-CD 3.28Å; G74-E79 PolarHBondContact N-OE1 3.09Å; G74-E79 PolarHBondContact N-OE2 2.92Å
75I94.8Very high95.7Very high78 Ų7847 Ų4740%0.428%0.277SS..SBendtrans-117.6-20.8-17866.7164.7000113.4Y70 H72 T73 E79 T189 L191Y70-I75 VanDerWaalsContact OH-CG1 3.31Å; Y70-I75 WeakPolarHBondContact OH-CG1 3.42Å; H72-I75 HydrophobicContact CB-CD1 3.34Å; H72-I75 HydrophobicContact CB-CG1 3.73Å; T73-I75 VanDerWaalsContact C-N 3.34Å; I75-E79 PolarHBondContact N-OE1 3.46Å; I75-T189 HydrophobicContact CD1-CG2 3.57Å; I75-T189 HydrophobicContact CG1-CG2 3.87Å; I75-L191 HydrophobicContact CD1-CD2 3.37Å
76D97Very high95.7Very high9 Ų943.8 Ų43.85%0.04826%0.256CS..  trans-115.4128.9178.4-159.9-62.7000111.3Y70 R78 E79 R187 T189Y70-D76 WeakPolarHBondContact OH-CB 3.35Å; D76-R78 PolarHBondContact O-N 3.44Å; D76-R78 VanDerWaalsContact OD1-CB 3.27Å; D76-R78 WeakPolarHBondContact OD1-CB 3Å; D76-R78 VanDerWaalsContact OD1-CG 3.31Å; D76-R78 WeakPolarHBondContact OD1-CG 3.48Å; D76-R78 IonicContact OD1-CZ 2.74Å; D76-R78 PolarHBondContact OD1-N 2.82Å; D76-R78 IonicContact OD1-NE 3.06Å; D76-R78 PolarHBondContact OD1-NE 3.38Å; D76-R78 IonicContact OD1-NH2 2.9Å; D76-R78 IonicContact OD2-CZ 2.56Å; D76-R78 IonicContact OD2-NE 3.86Å; D76-R78 PolarHBondContact OD2-NE 3.03Å; D76-R78 IonicContact OD2-NH2 3.82Å; D76-R78 PolarHBondContact OD2-NH2 3.4Å; D76-E79 HydrophobicContact CB-CG 4.19Å; D76-E79 PolarHBondContact N-OE1 3.47Å; D76-E79 VanDerWaalsContact O-CB 3.27Å; D76-E79 WeakPolarHBondContact O-CB 3.37Å; D76-E79 VanDerWaalsContact O-CG 3.3Å; D76-E79 WeakPolarHBondContact O-CG 3.36Å; D76-E79 PolarHBondContact O-N 3.43Å; D76-R187 IonicContact OD1-NH1 2.75Å; D76-R187 IonicContact OD2-NH1 3.11Å; D76-R187 PolarHBondContact OD2-NH1 3.27Å; D76-T189 HydrophobicContact CB-CG2 3.87Å; D76-T189 WeakPolarHBondContact OD2-CA 3.49Å; D76-T189 VanDerWaalsContact OD2-CB 3.31Å; D76-T189 WeakPolarHBondContact OD2-CB 3.32Å; D76-T189 PolarHBondContact OD2-OG1 3.25Å
77D97Very high95.8Very high27 Ų2743.4 Ų43.414%0.14425%0.254CS..THydrogen-bonded Turntrans-61.8-16.1-178.1-61-33.6000113.8E79 A84 F85 T156 R157D77-E79 VanDerWaalsContact C-N 3.34Å; D77-A84 HydrophobicContact CB-CB 4.03Å; D77-A84 WeakPolarHBondContact O-CB 3.35Å; D77-F85 HydrophobicContact CB-CE2 3.78Å; D77-F85 HydrophobicContact CB-CZ 4.07Å; D77-T156 VanDerWaalsContact OD2-CA 3.27Å; D77-T156 WeakPolarHBondContact OD2-CA 3.11Å; D77-T156 WeakPolarHBondContact OD2-CB 3.25Å; D77-R157 WeakPolarHBondContact OD1-CB 3.25Å; D77-R157 PolarHBondContact OD2-N 2.89Å
78R97.8Very high96Very high0 Ų046.1 Ų46.10%026%0.262CS..THydrogen-bonded Turntrans-82.7-14.3178.6-60.1173.7-68.61705.8112.4D76 R80 W81 Y184 V185 R187 F203 Y427 I430D76-R78 PolarHBondContact O-N 3.44Å; D76-R78 VanDerWaalsContact OD1-CB 3.27Å; D76-R78 WeakPolarHBondContact OD1-CB 3Å; D76-R78 VanDerWaalsContact OD1-CG 3.31Å; D76-R78 WeakPolarHBondContact OD1-CG 3.48Å; D76-R78 IonicContact OD1-CZ 2.74Å; D76-R78 PolarHBondContact OD1-N 2.82Å; D76-R78 IonicContact OD1-NE 3.06Å; D76-R78 PolarHBondContact OD1-NE 3.38Å; D76-R78 IonicContact OD1-NH2 2.9Å; D76-R78 IonicContact OD2-CZ 2.56Å; D76-R78 IonicContact OD2-NE 3.86Å; D76-R78 PolarHBondContact OD2-NE 3.03Å; D76-R78 IonicContact OD2-NH2 3.82Å; D76-R78 PolarHBondContact OD2-NH2 3.4Å; R78-R80 PolarHBondContact O-N 3.47Å; R78-W81 PolarHBondContact O-N 3.19Å; R78-Y184 WeakPolarHBondContact CD-O 3.47Å; R78-Y184 HydrophobicContact CG-CD1 4.18Å; R78-Y184 HydrophobicContact CG-CE1 3.48Å; R78-Y184 VanDerWaalsContact CG-CE1 3.48Å; R78-Y184 PolarHBondContact NH1-O 3.33Å; R78-V185 PolarHBondContact NH1-O 3.23Å; R78-R187 VanDerWaalsContact CZ-O 3.25Å; R78-R187 VanDerWaalsContact NH1-CG 3.29Å; R78-R187 PolarHBondContact NH1-O 3.48Å; R78-R187 PolarHBondContact NH2-O 3.3Å; R78-F203 HydrophobicContact CB-CD2 4.19Å; R78-F203 HydrophobicContact CB-CE1 4.14Å; R78-F203 HydrophobicContact CB-CE2 3.57Å; R78-F203 HydrophobicContact CB-CZ 3.53Å; R78-F203 HydrophobicContact CG-CE2 4.34Å; R78-Y427 PolarHBondContact O-OH 3.39Å; R78-Y427 VanDerWaalsContact O-OH 3.07Å; R78-I430 HydrophobicContact CB-CG1 4.34Å; R78-I430 HydrophobicContact CB-CG2 4.18Å; R78-I430 HydrophobicContact CG-CG2 3.84Å
79E97Very high96.1Very high25 Ų2541 Ų4112%0.11723%0.228CC..THydrogen-bonded Turntrans-61.1134.5170.9-65.4178.2-128.600110.3Y70 T73 G74 I75 D76 D77 W81 I421Y70-E79 HydrophobicContact CE1-CG 4.18Å; Y70-E79 PolarHBondContact OH-OE1 3.47Å; T73-E79 WeakPolarHBondContact CA-OE2 3.41Å; G74-E79 VanDerWaalsContact N-CD 3.28Å; G74-E79 PolarHBondContact N-OE1 3.09Å; G74-E79 PolarHBondContact N-OE2 2.92Å; I75-E79 PolarHBondContact N-OE1 3.46Å; D76-E79 HydrophobicContact CB-CG 4.19Å; D76-E79 PolarHBondContact N-OE1 3.47Å; D76-E79 VanDerWaalsContact O-CB 3.27Å; D76-E79 WeakPolarHBondContact O-CB 3.37Å; D76-E79 VanDerWaalsContact O-CG 3.3Å; D76-E79 WeakPolarHBondContact O-CG 3.36Å; D76-E79 PolarHBondContact O-N 3.43Å; D77-E79 VanDerWaalsContact C-N 3.34Å; E79-W81 PolarHBondContact O-N 3.01Å; E79-W81 VanDerWaalsContact O-N 3.13Å; E79-I421 HydrophobicContact CG-CD1 4.04Å
80R96.4Very high96.3Very high127 Ų12739.8 Ų39.848%0.47922%0.224SC..THydrogen-bonded Turntrans48.742.6179.3-54.7-172.968.1147.610.7112.6V61 D63 R78 L83 Y427V61-R80 HydrophobicContact CG2-CB 4.31Å; D63-R80 IonicContact OD1-CZ 2.78Å; D63-R80 IonicContact OD1-NH1 3.99Å; D63-R80 IonicContact OD1-NH2 3.91Å; D63-R80 PolarHBondContact OD1-NH2 3.26Å; R78-R80 PolarHBondContact O-N 3.47Å; R80-L83 HydrophobicContact CB-CD1 4.2Å; R80-L83 WeakPolarHBondContact O-CB 3.31Å; R80-L83 VanDerWaalsContact O-CG 3.3Å; R80-L83 WeakPolarHBondContact O-CG 3.39Å; R80-L83 PolarHBondContact O-N 2.88Å; R80-Y427 PolarHBondContact N-OH 2.93Å
81W97.6Very high96.4Very high1 Ų146.7 Ų46.70%0.00425%0.25CS..THydrogen-bonded Turntrans-48.2134.2-177.8177.1-102.5000112.5F21 R78 E79 F85 Y184 Y427 Y428 I430 P431 F432 L433F21-W81 AromaticContact CE1-CH2 3.54Å; F21-W81 HydrophobicContact CE1-CH2 3.54Å; F21-W81 HydrophobicContact CE1-CZ2 4.27Å; F21-W81 HydrophobicContact CE1-CZ3 4.3Å; F21-W81 AromaticContact CZ-CH2 3.98Å; F21-W81 HydrophobicContact CZ-CH2 3.98Å; F21-W81 HydrophobicContact CZ-CZ3 4.47Å; R78-W81 PolarHBondContact O-N 3.19Å; E79-W81 PolarHBondContact O-N 3.01Å; E79-W81 VanDerWaalsContact O-N 3.13Å; W81-F85 HydrophobicContact CH2-CD2 4.48Å; W81-F85 AromaticContact CZ3-CD2 3.89Å; W81-F85 HydrophobicContact CZ3-CD2 3.89Å; W81-F85 AromaticContact CZ3-CE2 3.95Å; W81-F85 HydrophobicContact CZ3-CE2 3.95Å; W81-Y184 HydrophobicContact CZ3-CE1 4.36Å; W81-Y427 HydrophobicContact CB-CE1 4.34Å; W81-Y428 WeakPolarHBondContact O-CD2 3.1Å; W81-I430 HydrophobicContact CB-CD1 4.32Å; W81-I430 HydrophobicContact CB-CG1 3.7Å; W81-I430 HydrophobicContact CD2-CG1 4.39Å; W81-I430 HydrophobicContact CD2-CG2 4.4Å; W81-I430 HydrophobicContact CE3-CG2 4.33Å; W81-I430 HydrophobicContact CG-CB 4.49Å; W81-I430 HydrophobicContact CG-CG1 3.91Å; W81-P431 HydrophobicContact CH2-CB 3.52Å; W81-P431 HydrophobicContact CZ2-CB 3.67Å; W81-P431 VanDerWaalsContact CZ2-O 3.26Å; W81-P431 WeakPolarHBondContact CZ2-O 3.22Å; W81-P431 HydrophobicContact CZ3-CB 4.04Å; W81-F432 PolarHBondContact NE1-O 2.8Å; W81-L433 HydrophobicContact CZ2-CD1 4.26Å; W81-L433 HydrophobicContact CZ2-CG 4.21Å
82P96.6Very high96.5Very high0 Ų044.5 Ų44.50%024%0.236CC..THydrogen-bonded Turncis-101.923.63.742.8-37.6000114V59 A84 F85 F86 L435V59-P82 HydrophobicContact CG1-CG 4.3Å; V59-P82 HydrophobicContact CG2-CG 4.45Å; P82-A84 PolarHBondContact O-N 3.02Å; P82-F85 PolarHBondContact O-N 2.92Å; P82-F86 PolarHBondContact O-N 3.33Å; P82-L435 HydrophobicContact CB-CD2 4.3Å; P82-L435 HydrophobicContact CG-CD1 4.13Å; P82-L435 HydrophobicContact CG-CD2 3.82Å
83L96.8Very high96.6Very high49 Ų4943.7 Ų43.726%0.25724%0.239SC..THydrogen-bonded Turntrans-63.6-18.6-162.6-65.4-176000115.8V59 V61 R80 F85 N87V59-L83 HydrophobicContact CB-CD2 4.09Å; V59-L83 HydrophobicContact CG1-CD2 4.29Å; V61-L83 HydrophobicContact CB-CD1 4.37Å; V61-L83 HydrophobicContact CG1-CD1 3.78Å; V61-L83 HydrophobicContact CG1-CD2 4.32Å; V61-L83 HydrophobicContact CG1-CG 3.8Å; V61-L83 HydrophobicContact CG2-CD1 3.63Å; R80-L83 HydrophobicContact CB-CD1 4.2Å; R80-L83 WeakPolarHBondContact O-CB 3.31Å; R80-L83 VanDerWaalsContact O-CG 3.3Å; R80-L83 WeakPolarHBondContact O-CG 3.39Å; R80-L83 PolarHBondContact O-N 2.88Å; L83-F85 PolarHBondContact O-N 3.01Å; L83-N87 HydrophobicContact CD2-CB 4.38Å
84A95.2Very high96.7Very high25 Ų2541 Ų4121%0.20724%0.236CC..THydrogen-bonded Turntrans-59-37.3169.500000111.5D77 P82 R157D77-A84 HydrophobicContact CB-CB 4.03Å; D77-A84 WeakPolarHBondContact O-CB 3.35Å; P82-A84 PolarHBondContact O-N 3.02Å; A84-R157 WeakPolarHBondContact O-CD 3.4Å; A84-R157 WeakPolarHBondContact O-CG 3.48Å; A84-R157 PolarHBondContact O-NE 3.49Å
85F95.8Very high96.9Very high0 Ų039.9 Ų39.90%021%0.213CC..THydrogen-bonded Turntrans-102.1-51.7-176.7-59.6-86.4000112.5F21 L31 D77 W81 P82 L83 R157 M160F21-F85 HydrophobicContact CE1-CB 3.94Å; F21-F85 HydrophobicContact CE1-CD1 4.21Å; F21-F85 AromaticContact CE1-CD2 3.94Å; F21-F85 HydrophobicContact CE1-CD2 3.94Å; F21-F85 AromaticContact CE1-CG 3.76Å; F21-F85 HydrophobicContact CE1-CG 3.76Å; F21-F85 AromaticContact CE2-CD1 3.85Å; F21-F85 HydrophobicContact CE2-CD1 3.85Å; F21-F85 AromaticContact CE2-CE1 3.94Å; F21-F85 HydrophobicContact CE2-CE1 3.94Å; F21-F85 HydrophobicContact CE2-CG 4.24Å; F21-F85 HydrophobicContact CE2-CZ 4.4Å; F21-F85 HydrophobicContact CZ-CB 4.09Å; F21-F85 AromaticContact CZ-CD1 3.5Å; F21-F85 HydrophobicContact CZ-CD1 3.5Å; F21-F85 VanDerWaalsContact CZ-CD1 3.5Å; F21-F85 AromaticContact CZ-CD2 3.59Å; F21-F85 HydrophobicContact CZ-CD2 3.59Å; F21-F85 AromaticContact CZ-CE1 3.74Å; F21-F85 HydrophobicContact CZ-CE1 3.74Å; F21-F85 AromaticContact CZ-CE2 3.81Å; F21-F85 HydrophobicContact CZ-CE2 3.81Å; F21-F85 AromaticContact CZ-CG 3.43Å; F21-F85 HydrophobicContact CZ-CG 3.43Å; F21-F85 VanDerWaalsContact CZ-CG 3.43Å; F21-F85 AromaticContact CZ-CZ 3.89Å; F21-F85 HydrophobicContact CZ-CZ 3.89Å; L31-F85 HydrophobicContact CD2-CD1 4.04Å; D77-F85 HydrophobicContact CB-CE2 3.78Å; D77-F85 HydrophobicContact CB-CZ 4.07Å; W81-F85 HydrophobicContact CH2-CD2 4.48Å; W81-F85 AromaticContact CZ3-CD2 3.89Å; W81-F85 HydrophobicContact CZ3-CD2 3.89Å; W81-F85 AromaticContact CZ3-CE2 3.95Å; W81-F85 HydrophobicContact CZ3-CE2 3.95Å; P82-F85 PolarHBondContact O-N 2.92Å; L83-F85 PolarHBondContact O-N 3.01Å; F85-R157 HydrophobicContact CE1-CB 4.05Å; F85-R157 HydrophobicContact CZ-CB 4.13Å; F85-M160 HydrophobicContact CE1-CE 4.44Å; F85-M160 HydrophobicContact CE1-SD 4.41Å
86F96.4Very high97Very high0 Ų038.7 Ų38.70%020%0.204CC..  trans-134.9129-170.7-57.5-75000111.9F21 C25 G30 K34 C36 P82 T89 L433F21-F86 HydrophobicContact CB-CE2 3.94Å; F21-F86 HydrophobicContact CB-CZ 4.27Å; F21-F86 AromaticContact CD1-CD2 3.87Å; F21-F86 HydrophobicContact CD1-CD2 3.87Å; F21-F86 AromaticContact CD1-CE2 3.25Å; F21-F86 HydrophobicContact CD1-CE2 3.25Å; F21-F86 HydrophobicContact CD1-CZ 4.29Å; F21-F86 HydrophobicContact CD2-CE2 4.42Å; F21-F86 HydrophobicContact CE1-CD2 4.16Å; F21-F86 AromaticContact CE1-CE2 3.77Å; F21-F86 HydrophobicContact CE1-CE2 3.77Å; F21-F86 AromaticContact CG-CE2 3.62Å; F21-F86 HydrophobicContact CG-CE2 3.62Å; F21-F86 HydrophobicContact CG-CZ 4.27Å; C25-F86 HydrophobicContact CB-CE1 4.2Å; C25-F86 HydrophobicContact CB-CZ 3.97Å; G30-F86 WeakPolarHBondContact O-CE1 3.37Å; K34-F86 CarbonylContact O-C 3.43Å; K34-F86 WeakPolarHBondContact O-CA 3.11Å; C36-F86 HydrophobicContact CB-CB 4.41Å; C36-F86 HydrophobicContact CB-CD1 3.51Å; C36-F86 HydrophobicContact CB-CD2 4.12Å; C36-F86 HydrophobicContact CB-CE1 3.71Å; C36-F86 HydrophobicContact CB-CE2 4.34Å; C36-F86 HydrophobicContact CB-CG 3.73Å; C36-F86 HydrophobicContact CB-CZ 4.14Å; P82-F86 PolarHBondContact O-N 3.33Å; F86-T89 HydrophobicContact CB-CG2 4.19Å; F86-L433 HydrophobicContact CD2-CD1 4.4Å
87N97.4Very high97Very high55 Ų5538.8 Ų38.829%0.29421%0.207SC..SBendtrans-97-13.1169.966.4-2.1000112.2K34 E58 V59 L83K34-N87 HydrophobicContact CB-CB 4.45Å; K34-N87 WeakPolarHBondContact CB-OD1 3.05Å; K34-N87 PolarHBondContact O-N 2.95Å; K34-N87 PolarHBondContact O-OD1 3.25Å; E58-N87 CarbonylContact C-O 3.4Å; E58-N87 WeakPolarHBondContact CA-O 3.31Å; V59-N87 PolarHBondContact N-O 2.92Å; L83-N87 HydrophobicContact CD2-CB 4.38Å
88R98Very high96.8Very high64 Ų6437.8 Ų37.824%0.24220%0.204CC..EExtended strand (participates in β ladder)trans-129.1130177.5-67177.16675.37.3111.1K34 E35 C36 C56 T57 E58K34-R88 PolarHBondContact O-N 2.95Å; K34-R88 VanDerWaalsContact O-N 3.15Å; E35-R88 HydrophobicContact CB-CB 4.17Å; E35-R88 HydrophobicContact CG-CB 3.89Å; E35-R88 WeakPolarHBondContact OE2-CD 3.39Å; E35-R88 IonicContact OE2-CZ 2.69Å; E35-R88 IonicContact OE2-NE 2.62Å; E35-R88 PolarHBondContact OE2-NE 3.03Å; E35-R88 IonicContact OE2-NH2 3.69Å; C36-R88 PolarHBondContact N-O 3.17Å; C56-R88 PolarHBondContact O-NH2 3.33Å; T57-R88 VanDerWaalsContact O-CA 3.3Å; T57-R88 WeakPolarHBondContact O-CA 3.32Å; E58-R88 WeakPolarHBondContact OE1-CD 3.41Å; E58-R88 WeakPolarHBondContact OE1-CG 3.44Å; E58-R88 IonicContact OE1-CZ 2.82Å; E58-R88 IonicContact OE1-NE 3.45Å; E58-R88 IonicContact OE1-NH1 2.83Å; E58-R88 PolarHBondContact OE1-NH1 2.9Å
89T97.8Very high96.7Very high13 Ų1338.6 Ų38.68%0.0821%0.207CC..EExtended strand (participates in β ladder)trans-141.4166.6177.663.10000111.5C36 T57 V59 F86 R91 L433C36-T89 HydrophobicContact CB-CG2 4.47Å; C36-T89 WeakPolarHBondContact O-CA 3.42Å; T57-T89 PolarHBondContact N-O 3Å; T57-T89 PolarHBondContact O-N 3.47Å; V59-T89 HydrophobicContact CG2-CG2 3.75Å; V59-T89 WeakPolarHBondContact CG2-OG1 3.38Å; F86-T89 HydrophobicContact CB-CG2 4.19Å; T89-R91 PolarHBondContact O-N 2.83Å; T89-L433 HydrophobicContact CG2-CD2 4.07Å
90C97.6Very high96.7Very high12 Ų1238.4 Ų38.48%0.08121%0.207CC..EExtended strand (participates in β ladder)trans-67.7125.5174.1-68.10000112C47 F99C47-C90 WeakPolarHBondContact CA-SG 3.19Å; C47-C90 HydrophobicContact CB-CB 3.68Å; C47-C90 WeakPolarHBondContact CB-SG 3.48Å; C47-C90 WeakPolarHBondContact SG-CA 3.5Å; C47-C90 WeakPolarHBondContact SG-CB 3.31Å; C47-C90 CovalentContact SG-SG 2.03Å; C47-C90 PolarHBondContact SG-SG 3.39Å; C90-F99 WeakPolarHBondContact CB-O 3.29Å; C90-F99 PolarHBondContact SG-O 3.05Å; C90-F99 VanDerWaalsContact SG-O 3.37Å
91R97Very high96.8Very high163 Ų16332.3 Ų32.362%0.61518%0.184SC*.EExtended strand (participates in β ladder)trans-106.5112.1166.3-176.4178.467.6177.60.1109.6G54 F55 T57 T89G54-R91 WeakPolarHBondContact CA-O 3.22Å; F55-R91 PolarHBondContact N-O 3.26Å; F55-R91 PolarHBondContact O-N 3.48Å; T57-R91 HydrophobicContact CG2-CB 4.36Å; T57-R91 WeakPolarHBondContact OG1-CB 3.24Å; T89-R91 PolarHBondContact O-N 2.83Å
92C97.5Very high96.7Very high37 Ų3733.3 Ų33.325%0.2519%0.194CC..EExtended strand (participates in β ladder)trans-79.7147.8-177.3-500000112.1R53 Y96 C101R53-C92 CarbonylContact O-C 3.53Å; R53-C92 WeakPolarHBondContact O-CA 3.35Å; C92-Y96 WeakPolarHBondContact CB-O 3.34Å; C92-C101 WeakPolarHBondContact CA-SG 3.28Å; C92-C101 HydrophobicContact CB-CB 3.76Å; C92-C101 WeakPolarHBondContact CB-SG 3.28Å; C92-C101 PolarHBondContact N-SG 3.48Å; C92-C101 WeakPolarHBondContact SG-CA 3.43Å; C92-C101 WeakPolarHBondContact SG-CB 3.46Å; C92-C101 CovalentContact SG-SG 2.05Å; C92-C101 PolarHBondContact SG-SG 3.23Å
93A97.3Very high96.6Very high36 Ų3635.3 Ų35.330%0.29820%0.204SC..  trans-93.9144179.800000110.9R53 N95 Y96R53-A93 PolarHBondContact O-N 3.24Å; A93-N95 PolarHBondContact O-N 3.46Å; A93-N95 VanDerWaalsContact O-N 3.16Å; A93-Y96 WeakPolarHBondContact O-CB 3.18Å; A93-Y96 WeakPolarHBondContact O-CD2 3.43Å; A93-Y96 PolarHBondContact O-N 2.9Å; A93-Y96 VanDerWaalsContact O-N 3.07Å
94G96.2Very high96.6Very high68 Ų6834.5 Ų34.570%0.70120%0.202SC*.THydrogen-bonded Turntrans54.6-120.1174.100000113.4
95N97.3Very high96.6Very high49 Ų4938 Ų3826%0.26221%0.21SC..THydrogen-bonded Turntrans-10012.2-177.7-63.2-28.6000113.4A93 C104 R105 Y108 C113A93-N95 PolarHBondContact O-N 3.46Å; A93-N95 VanDerWaalsContact O-N 3.16Å; N95-C104 CarbonylContact O-C 3.55Å; N95-C104 WeakPolarHBondContact O-CA 3.37Å; N95-R105 WeakPolarHBondContact O-CB 3.41Å; N95-R105 PolarHBondContact O-N 2.75Å; N95-Y108 HydrophobicContact CB-CD1 4.01Å; N95-Y108 HydrophobicContact CB-CD2 4.09Å; N95-Y108 HydrophobicContact CB-CE1 4.45Å; N95-Y108 HydrophobicContact CB-CG 3.79Å; N95-Y108 VanDerWaalsContact ND2-CD1 3.33Å; N95-Y108 WeakPolarHBondContact ND2-CD1 3.48Å; N95-Y108 WeakPolarHBondContact ND2-CE1 3.43Å; N95-C113 HydrophobicContact CB-CB 3.96Å; N95-C113 WeakPolarHBondContact CB-O 3.23Å; N95-C113 VanDerWaalsContact O-CB 3.31Å; N95-C113 WeakPolarHBondContact O-CB 3.41Å
96Y97.9Very high96.6Very high52 Ų5239.1 Ų39.120%0.20422%0.215CC..EExtended strand (participates in β ladder)trans-76.7153.4171.5-60.9-64.3000110.7R53 C92 A93 E103 C113R53-Y96 HydrophobicContact CB-CD1 4.47Å; R53-Y96 HydrophobicContact CB-CD2 4Å; R53-Y96 HydrophobicContact CB-CE2 4.33Å; R53-Y96 HydrophobicContact CB-CG 4.08Å; R53-Y96 HydrophobicContact CG-CD1 4.01Å; R53-Y96 HydrophobicContact CG-CD2 4.02Å; R53-Y96 HydrophobicContact CG-CE1 3.93Å; R53-Y96 HydrophobicContact CG-CE2 3.93Å; R53-Y96 HydrophobicContact CG-CG 4.07Å; C92-Y96 WeakPolarHBondContact CB-O 3.34Å; A93-Y96 WeakPolarHBondContact O-CB 3.18Å; A93-Y96 WeakPolarHBondContact O-CD2 3.43Å; A93-Y96 PolarHBondContact O-N 2.9Å; A93-Y96 VanDerWaalsContact O-N 3.07Å; Y96-E103 WeakPolarHBondContact CA-O 3.2Å; Y96-C113 HydrophobicContact CD1-CB 4.06Å; Y96-C113 WeakPolarHBondContact CD1-SG 3.46Å; Y96-C113 HydrophobicContact CE1-CB 4.14Å
97G95.7Very high96.5Very high12 Ų1239.5 Ų39.512%0.12422%0.218CC..EExtended strand (participates in β ladder)trans-154.3-172-177.500000112.2C101 G102 E103G97-C101 CarbonylContact O-C 3.3Å; G97-C101 VanDerWaalsContact O-C 3.27Å; G97-C101 WeakPolarHBondContact O-CA 3.47Å; G97-G102 PolarHBondContact O-N 3.24Å; G97-E103 PolarHBondContact N-O 3.1Å; G97-E103 CarbonylContact O-C 3.48Å; G97-E103 WeakPolarHBondContact O-CA 3.36Å; G97-E103 WeakPolarHBondContact O-CB 3.4Å; G97-E103 PolarHBondContact O-N 2.79Å
98G94.8Very high96.5Very high6 Ų640 Ų406%0.06222%0.216CC..SBendtrans80.4167.5-174.100000112.8N100 C101G98-N100 PolarHBondContact O-N 2.84Å; G98-C101 PolarHBondContact O-N 2.72Å
99F95.1Very high96.4Very high16 Ų1638.9 Ų38.97%0.0721%0.212CC..THydrogen-bonded Turntrans-68.6-19.5-170.564.4-98000114.7P22 P38 C90 D149 Y150P22-F99 HydrophobicContact CB-CB 4.07Å; P22-F99 HydrophobicContact CB-CD1 4.24Å; P22-F99 HydrophobicContact CB-CD2 3.49Å; P22-F99 VanDerWaalsContact CB-CD2 3.49Å; P22-F99 HydrophobicContact CB-CE2 3.92Å; P22-F99 HydrophobicContact CB-CG 3.66Å; P22-F99 HydrophobicContact CB-CZ 4.47Å; P22-F99 HydrophobicContact CG-CB 3.33Å; P22-F99 HydrophobicContact CG-CD1 4.22Å; P22-F99 HydrophobicContact CG-CD2 3.77Å; P22-F99 HydrophobicContact CG-CG 3.51Å; P38-F99 HydrophobicContact CB-CD2 4.13Å; P38-F99 HydrophobicContact CB-CE2 4.02Å; P38-F99 HydrophobicContact CG-CD2 3.8Å; P38-F99 HydrophobicContact CG-CE2 4.08Å; C90-F99 WeakPolarHBondContact CB-O 3.29Å; C90-F99 PolarHBondContact SG-O 3.05Å; C90-F99 VanDerWaalsContact SG-O 3.37Å; F99-D149 HydrophobicContact CE1-CB 3.77Å; F99-D149 HydrophobicContact CZ-CB 4.44Å; F99-Y150 HydrophobicContact CD1-CE1 4.35Å; F99-Y150 HydrophobicContact CD1-CE2 4.47Å; F99-Y150 AromaticContact CD1-CZ 3.93Å
100N96.6Very high96.1Very high21 Ų2140 Ų4011%0.11223%0.226CC..THydrogen-bonded Turntrans-119.613.4176.466.2-2000112.6P38 V39 C47 G98 G102P38-N100 HydrophobicContact CB-CB 4.14Å; V39-N100 PolarHBondContact O-ND2 2.78Å; C47-N100 CarbonylContact C-O 3.6Å; C47-N100 WeakPolarHBondContact CA-O 3.23Å; G98-N100 PolarHBondContact O-N 2.84Å; N100-G102 PolarHBondContact O-N 2.83Å; N100-G102 WeakPolarHBondContact OD1-CA 3.14Å; N100-G102 PolarHBondContact OD1-N 3.1Å
101C97.9Very high95.9Very high0 Ų042.6 Ų42.60%026%0.255CS..SBendtrans61.515.9-175-51.60000115.4C47 R53 C92 G97 G98C47-C101 WeakPolarHBondContact O-CB 3.45Å; R53-C101 HydrophobicContact CB-CB 4.03Å; R53-C101 WeakPolarHBondContact CD-O 3.4Å; R53-C101 PolarHBondContact NH1-O 3.5Å; R53-C101 VanDerWaalsContact NH1-O 3.17Å; C92-C101 WeakPolarHBondContact CA-SG 3.28Å; C92-C101 HydrophobicContact CB-CB 3.76Å; C92-C101 WeakPolarHBondContact CB-SG 3.28Å; C92-C101 PolarHBondContact N-SG 3.48Å; C92-C101 WeakPolarHBondContact SG-CA 3.43Å; C92-C101 WeakPolarHBondContact SG-CB 3.46Å; C92-C101 CovalentContact SG-SG 2.05Å; C92-C101 PolarHBondContact SG-SG 3.23Å; G97-C101 CarbonylContact O-C 3.3Å; G97-C101 VanDerWaalsContact O-C 3.27Å; G97-C101 WeakPolarHBondContact O-CA 3.47Å; G98-C101 PolarHBondContact O-N 2.72Å
102G95.9Very high95.7Very high22 Ų2239.4 Ų39.423%0.22725%0.25CS..  trans-78.2-21.2176.800000114.3W40 R53 G97 N100W40-G102 VanDerWaalsContact NE1-CA 3.26Å; R53-G102 PolarHBondContact NH1-O 3.43Å; G97-G102 PolarHBondContact O-N 3.24Å; N100-G102 PolarHBondContact O-N 2.83Å; N100-G102 WeakPolarHBondContact OD1-CA 3.14Å; N100-G102 PolarHBondContact OD1-N 3.1Å
103E95.4Very high95.7Very high42 Ų4237.8 Ų37.820%0.19624%0.239CC..EExtended strand (participates in β ladder)trans-95-176.1-179.9-56.4-175.4-15200111Y96 G97 N223 K227Y96-E103 WeakPolarHBondContact CA-O 3.2Å; G97-E103 PolarHBondContact N-O 3.1Å; G97-E103 CarbonylContact O-C 3.48Å; G97-E103 WeakPolarHBondContact O-CA 3.36Å; G97-E103 WeakPolarHBondContact O-CB 3.4Å; G97-E103 PolarHBondContact O-N 2.79Å; E103-N223 PolarHBondContact OE2-ND2 3.23Å; E103-K227 IonicContact OE1-NZ 3.68Å; E103-K227 PolarHBondContact OE1-NZ 2.72Å
104C96.3Very high95.7Very high31 Ų3139.2 Ų39.221%0.20925%0.251CS..EExtended strand (participates in β ladder)trans-108.4150.1173.6-60.30000110.7N95 Y108 G110 C113N95-C104 CarbonylContact O-C 3.55Å; N95-C104 WeakPolarHBondContact O-CA 3.37Å; C104-Y108 WeakPolarHBondContact CB-O 3.49Å; C104-G110 PolarHBondContact SG-O 3.11Å; C104-C113 WeakPolarHBondContact CA-SG 3.03Å; C104-C113 HydrophobicContact CB-CB 3.71Å; C104-C113 WeakPolarHBondContact CB-SG 3.31Å; C104-C113 WeakPolarHBondContact SG-CA 3.42Å; C104-C113 WeakPolarHBondContact SG-CB 3.36Å; C104-C113 CovalentContact SG-SG 2.04Å; C104-C113 PolarHBondContact SG-SG 2.93Å
105R95.6Very high95.7Very high99 Ų9941.9 Ų41.937%0.37425%0.245SC..  trans-56.4146.9167.1-176177.3-177.6177.82.9109.4N95 G107 Y108N95-R105 WeakPolarHBondContact O-CB 3.41Å; N95-R105 PolarHBondContact O-N 2.75Å; R105-G107 PolarHBondContact O-N 3.45Å; R105-Y108 HydrophobicContact CB-CD2 4.34Å; R105-Y108 WeakPolarHBondContact O-CB 3.28Å; R105-Y108 PolarHBondContact O-N 3.02Å
106F95.3Very high95.6Very high24 Ų2444.6 Ų44.611%0.10525%0.253CS..THydrogen-bonded Turntrans-46.9130.2177.8-57.3-54.5000112.1Y108 L219 Y436 Y441 L448F106-Y108 VanDerWaalsContact C-N 3.34Å; F106-L219 HydrophobicContact CD1-CB 4.03Å; F106-L219 HydrophobicContact CD1-CD2 4.4Å; F106-L219 HydrophobicContact CD2-CB 4.33Å; F106-L219 HydrophobicContact CD2-CD1 3.84Å; F106-L219 HydrophobicContact CE1-CB 3.71Å; F106-L219 HydrophobicContact CE2-CB 4.02Å; F106-L219 HydrophobicContact CE2-CD1 4.12Å; F106-L219 HydrophobicContact CG-CB 4.33Å; F106-L219 HydrophobicContact CG-CD1 4.09Å; F106-L219 HydrophobicContact CG-CD2 4.45Å; F106-L219 HydrophobicContact CZ-CB 3.71Å; F106-Y436 HydrophobicContact CE2-CE1 4.21Å; F106-Y441 AromaticContact CD2-CE1 3.97Å; F106-Y441 HydrophobicContact CD2-CE1 3.97Å; F106-Y441 HydrophobicContact CE2-CE1 4.09Å; F106-L448 CarbonylContact C-O 3.56Å; F106-L448 VanDerWaalsContact C-O 3.3Å; F106-L448 HydrophobicContact CB-CB 4.43Å
107G95.1Very high95.3Very high7 Ų745.8 Ų45.87%0.07226%0.257CS..THydrogen-bonded Turntrans88.2-11.8-177.100000115.9R105 Y116 R117 L448R105-G107 PolarHBondContact O-N 3.45Å; G107-Y116 WeakPolarHBondContact O-CA 3.41Å; G107-Y116 WeakPolarHBondContact O-CD2 3.45Å; G107-R117 PolarHBondContact O-N 2.99Å; G107-L448 WeakPolarHBondContact CA-O 3.11Å; G107-L448 PolarHBondContact N-O 2.99Å; G107-L448 VanDerWaalsContact N-O 3.13Å
108Y96.9Very high95.2Very high66 Ų6648 Ų4826%0.25926%0.264SS..EExtended strand (participates in β ladder)trans-105.6149.5175.8-66.7-89000111.9N95 C104 R105 F106 C113 Q115 Y116N95-Y108 HydrophobicContact CB-CD1 4.01Å; N95-Y108 HydrophobicContact CB-CD2 4.09Å; N95-Y108 HydrophobicContact CB-CE1 4.45Å; N95-Y108 HydrophobicContact CB-CG 3.79Å; N95-Y108 VanDerWaalsContact ND2-CD1 3.33Å; N95-Y108 WeakPolarHBondContact ND2-CD1 3.48Å; N95-Y108 WeakPolarHBondContact ND2-CE1 3.43Å; C104-Y108 WeakPolarHBondContact CB-O 3.49Å; R105-Y108 HydrophobicContact CB-CD2 4.34Å; R105-Y108 WeakPolarHBondContact O-CB 3.28Å; R105-Y108 PolarHBondContact O-N 3.02Å; F106-Y108 VanDerWaalsContact C-N 3.34Å; Y108-C113 WeakPolarHBondContact CD1-O 3.33Å; Y108-Q115 CarbonylContact C-O 3.6Å; Y108-Q115 WeakPolarHBondContact CA-O 3.03Å; Y108-Y116 HydrophobicContact CE1-CD2 4.41Å
109W94.9Very high95.2Very high41 Ų4148.2 Ų48.216%0.15526%0.264CS..EExtended strand (participates in β ladder)trans-147.8170.7-170.4-57.785.1000111.5C113 A114 Q115 R117 F232W109-C113 CarbonylContact O-C 3.33Å; W109-C113 VanDerWaalsContact O-CA 3.31Å; W109-C113 WeakPolarHBondContact O-CA 3.26Å; W109-A114 PolarHBondContact O-N 3.22Å; W109-Q115 HydrophobicContact CB-CB 4.3Å; W109-Q115 PolarHBondContact N-O 3.4Å; W109-Q115 WeakPolarHBondContact O-CB 3.31Å; W109-Q115 PolarHBondContact O-N 3.39Å; W109-Q115 VanDerWaalsContact O-N 3.1Å; W109-R117 VanDerWaalsContact CD1-CB 3.45Å; W109-R117 HydrophobicContact CG-CB 4.32Å; W109-R117 PolarHBondContact NE1-O 3.35Å; W109-F232 HydrophobicContact CH2-CB 4.16Å; W109-F232 HydrophobicContact CH2-CD1 4.34Å; W109-F232 WeakPolarHBondContact CH2-O 3.24Å; W109-F232 HydrophobicContact CZ3-CB 3.69Å; W109-F232 AromaticContact CZ3-CD1 3.65Å; W109-F232 HydrophobicContact CZ3-CD1 3.65Å; W109-F232 AromaticContact CZ3-CG 3.97Å; W109-F232 HydrophobicContact CZ3-CG 3.97Å
110G92.9Very high95.2Very high35 Ų3549 Ų4936%0.36127%0.27SS..SBendtrans87.1167.1178.300000112.9C104 N112 C113C104-G110 PolarHBondContact SG-O 3.11Å; G110-N112 PolarHBondContact O-N 3.24Å; G110-C113 PolarHBondContact O-N 3.24Å
111G91.9Very high95.3Very high68 Ų6848 Ų4870%0.70127%0.265SS*.THydrogen-bonded Turntrans-60.2-21.4-172.800000115R53R53-G111 PolarHBondContact NH2-O 3.42Å
112N94.4Very high95.3Very high96 Ų9649.6 Ų49.651%0.51327%0.271SS..THydrogen-bonded Turntrans-118.312.1177.366.3-12.6000113.2G110 A114G110-N112 PolarHBondContact O-N 3.24Å; N112-A114 PolarHBondContact O-N 2.94Å; N112-A114 VanDerWaalsContact O-N 3.13Å; N112-A114 VanDerWaalsContact OD1-CB 3.25Å; N112-A114 WeakPolarHBondContact OD1-CB 3.4Å; N112-A114 PolarHBondContact OD1-N 3.12Å
113C96.8Very high95.4Very high2 Ų249.6 Ų49.61%0.01427%0.266CS..SBendtrans54.530.8-178.7-530000114.7N95 Y96 C104 Y108 W109 G110N95-C113 HydrophobicContact CB-CB 3.96Å; N95-C113 WeakPolarHBondContact CB-O 3.23Å; N95-C113 VanDerWaalsContact O-CB 3.31Å; N95-C113 WeakPolarHBondContact O-CB 3.41Å; Y96-C113 HydrophobicContact CD1-CB 4.06Å; Y96-C113 WeakPolarHBondContact CD1-SG 3.46Å; Y96-C113 HydrophobicContact CE1-CB 4.14Å; C104-C113 WeakPolarHBondContact CA-SG 3.03Å; C104-C113 HydrophobicContact CB-CB 3.71Å; C104-C113 WeakPolarHBondContact CB-SG 3.31Å; C104-C113 WeakPolarHBondContact SG-CA 3.42Å; C104-C113 WeakPolarHBondContact SG-CB 3.36Å; C104-C113 CovalentContact SG-SG 2.04Å; C104-C113 PolarHBondContact SG-SG 2.93Å; Y108-C113 WeakPolarHBondContact CD1-O 3.33Å; W109-C113 CarbonylContact O-C 3.33Å; W109-C113 VanDerWaalsContact O-CA 3.31Å; W109-C113 WeakPolarHBondContact O-CA 3.26Å; G110-C113 PolarHBondContact O-N 3.24Å
114A96.8Very high95.5Very high67 Ų6747.6 Ų47.655%0.55426%0.256SS*.  trans-93.3-8.9179.600000113.6W109 N112W109-A114 PolarHBondContact O-N 3.22Å; N112-A114 PolarHBondContact O-N 2.94Å; N112-A114 VanDerWaalsContact O-N 3.13Å; N112-A114 VanDerWaalsContact OD1-CB 3.25Å; N112-A114 WeakPolarHBondContact OD1-CB 3.4Å; N112-A114 PolarHBondContact OD1-N 3.12Å
115Q96Very high95.5Very high124 Ų12449.9 Ų49.958%0.57927%0.265SS*.EExtended strand (participates in β ladder)trans-97.9108.7-177.2-59.31772.800109.7Y108 W109Y108-Q115 CarbonylContact C-O 3.6Å; Y108-Q115 WeakPolarHBondContact CA-O 3.03Å; W109-Q115 HydrophobicContact CB-CB 4.3Å; W109-Q115 PolarHBondContact N-O 3.4Å; W109-Q115 WeakPolarHBondContact O-CB 3.31Å; W109-Q115 PolarHBondContact O-N 3.39Å; W109-Q115 VanDerWaalsContact O-N 3.1Å
116Y95.9Very high95.5Very high106 Ų10649.6 Ų49.642%0.41627%0.274SS..EExtended strand (participates in β ladder)trans-78.9130.7169.8175.8-92.5000109.8G107 Y108 E118 K446G107-Y116 WeakPolarHBondContact O-CA 3.41Å; G107-Y116 WeakPolarHBondContact O-CD2 3.45Å; Y108-Y116 HydrophobicContact CE1-CD2 4.41Å; Y116-E118 HydrophobicContact CE1-CB 4.47Å; Y116-K446 PolarHBondContact OH-O 3.46Å
117R92.3Very high95.5Very high77 Ų7749.7 Ų49.729%0.29128%0.275SS..  trans-142125.6176.7-170.5-171.972.9171.810.5110.5G107 W109 F232 N233G107-R117 PolarHBondContact O-N 2.99Å; W109-R117 VanDerWaalsContact CD1-CB 3.45Å; W109-R117 HydrophobicContact CG-CB 4.32Å; W109-R117 PolarHBondContact NE1-O 3.35Å; R117-F232 PolarHBondContact NH2-O 2.96Å; R117-N233 PolarHBondContact NH1-OD1 3.43Å
118E92.6Very high95.5Very high59 Ų5951.9 Ų51.928%0.27629%0.29SS..  trans-86136.4174.1-164177.597.500110.8Y116 G449 E451Y116-E118 HydrophobicContact CE1-CB 4.47Å; E118-G449 CarbonylContact C-O 3.47Å; E118-G449 VanDerWaalsContact CA-O 3.31Å; E118-G449 WeakPolarHBondContact CA-O 3.44Å; E118-E451 HydrophobicContact CG-CB 4.16Å; E118-E451 WeakPolarHBondContact OE1-CB 3.22Å
119S94.4Very high95.4Very high10 Ų1053 Ų537%0.0730%0.303CS..EExtended strand (participates in β ladder)trans-112.1144.8173.6-47.50000110.2T235 G449 Y450 E451S119-T235 VanDerWaalsContact CB-CG2 3.46Å; S119-G449 PolarHBondContact N-O 3.15Å; S119-Y450 CarbonylContact O-C 3.23Å; S119-Y450 WeakPolarHBondContact O-CA 3.3Å; S119-Y450 WeakPolarHBondContact O-CB 3.46Å; S119-E451 PolarHBondContact O-N 3.33Å
120V95.9Very high95.5Very high31 Ų3154.1 Ų54.119%0.18832%0.322CS..EExtended strand (participates in β ladder)trans-106.6123.3-177.2-177.40000110.7R122 T235 E451 A453 L456 Q464V120-R122 HydrophobicContact CG1-CG 4.38Å; V120-T235 PolarHBondContact O-OG1 2.87Å; V120-E451 CarbonylContact C-O 3.53Å; V120-E451 WeakPolarHBondContact CA-O 3.38Å; V120-A453 HydrophobicContact CG1-CB 3.82Å; V120-L456 HydrophobicContact CG1-CD1 4.24Å; V120-Q464 HydrophobicContact CG1-CG 4.41Å
121R98Very high95.7Very high0 Ų054.2 Ų54.20%031%0.313CS..EExtended strand (participates in β ladder)trans-84.3128.2168.5-65.9-173.6171.2168.3-1.3109.2E222 I236 Y238 D397 Y450 E451 Y452 A453R121-E222 IonicContact CZ-OE1 3.62Å; R121-E222 IonicContact NE-OE1 2.69Å; R121-E222 PolarHBondContact NE-OE1 2.82Å; R121-E222 VanDerWaalsContact NE-OE1 3.13Å; R121-E222 IonicContact NH2-OE1 4Å; R121-E222 PolarHBondContact NH2-OE1 3.17Å; R121-I236 VanDerWaalsContact CD-O 3.28Å; R121-I236 WeakPolarHBondContact CD-O 3.29Å; R121-I236 WeakPolarHBondContact CG-O 3.45Å; R121-Y238 HydrophobicContact CB-CD1 4.46Å; R121-Y238 WeakPolarHBondContact O-CE1 3.48Å; R121-D397 IonicContact NH1-OD2 3.42Å; R121-Y450 HydrophobicContact CG-CD2 4.39Å; R121-E451 PolarHBondContact N-O 3.16Å; R121-Y452 HydrophobicContact CB-CD1 3.74Å; R121-Y452 HydrophobicContact CB-CE1 3.7Å; R121-Y452 HydrophobicContact CG-CE1 4.29Å; R121-Y452 PolarHBondContact NH1-OH 2.99Å; R121-Y452 VanDerWaalsContact NH1-OH 3.08Å; R121-A453 PolarHBondContact O-N 2.88Å
122R97.1Very high96Very high34 Ų3452.1 Ų52.113%0.12829%0.285CS..  trans-111.5157.3-174.3-59.5179.272.6-173.41.3111.2V120 I124 M127 E131 P237 Y238 A453V120-R122 HydrophobicContact CG1-CG 4.38Å; R122-I124 PolarHBondContact O-N 3.46Å; R122-M127 HydrophobicContact CB-CG 3.87Å; R122-M127 HydrophobicContact CB-SD 4.09Å; R122-E131 IonicContact CZ-OE1 3.05Å; R122-E131 VanDerWaalsContact NH1-CD 3.28Å; R122-E131 IonicContact NH1-OE1 3.84Å; R122-E131 PolarHBondContact NH1-OE1 2.91Å; R122-E131 IonicContact NH1-OE2 2.78Å; R122-E131 PolarHBondContact NH1-OE2 2.89Å; R122-E131 VanDerWaalsContact NH1-OE2 3.1Å; R122-P237 VanDerWaalsContact O-CA 3.28Å; R122-P237 WeakPolarHBondContact O-CA 3.16Å; R122-P237 VanDerWaalsContact O-CB 3.22Å; R122-P237 WeakPolarHBondContact O-CB 3.03Å; R122-Y238 VanDerWaalsContact C-CD1 3.49Å; R122-Y238 VanDerWaalsContact O-CD1 3.28Å; R122-Y238 WeakPolarHBondContact O-CD1 3.45Å; R122-Y238 PolarHBondContact O-N 3.48Å; R122-A453 HydrophobicContact CG-CB 4.36Å
123N98.2Very high96.1Very high22 Ų2252.9 Ų52.912%0.11829%0.285CS..BIsolated β-bridgetrans-71.3121.8171.6-174.6-23.5000108.3M125 T126 M127 Y238 D240N123-M125 PolarHBondContact O-N 3.23Å; N123-M125 VanDerWaalsContact O-N 3.12Å; N123-M125 WeakPolarHBondContact OD1-CB 3.34Å; N123-M125 PolarHBondContact OD1-N 2.76Å; N123-T126 HydrophobicContact CB-CG2 4.32Å; N123-T126 PolarHBondContact O-N 2.61Å; N123-T126 PolarHBondContact O-OG1 3.43Å; N123-M127 PolarHBondContact O-N 2.54Å; N123-Y238 WeakPolarHBondContact CA-O 3.33Å; N123-Y238 HydrophobicContact CB-CD2 4.24Å; N123-Y238 HydrophobicContact CB-CE1 4.31Å; N123-Y238 HydrophobicContact CB-CE2 3.55Å; N123-Y238 VanDerWaalsContact N-CE1 3.27Å; N123-D240 WeakPolarHBondContact ND2-CB 3.15Å
124I98.4Very high96.2Very high0 Ų056.4 Ų56.40%030%0.3CS..G310 helixtrans-56.4-31.8-178.2-165167.5000112.7R122 T126 M127 Q132 F135 P237 Y238 W239 V249 L254 M255 L391R122-I124 PolarHBondContact O-N 3.46Å; I124-T126 PolarHBondContact O-N 3.1Å; I124-M127 HydrophobicContact CB-SD 4.44Å; I124-M127 HydrophobicContact CG1-SD 4.45Å; I124-M127 PolarHBondContact O-N 3.27Å; I124-Q132 HydrophobicContact CG1-CG 4.25Å; I124-Q132 PolarHBondContact O-NE2 2.9Å; I124-F135 HydrophobicContact CD1-CD1 4.13Å; I124-F135 HydrophobicContact CD1-CE1 4.39Å; I124-P237 HydrophobicContact CB-CB 4.14Å; I124-P237 HydrophobicContact CB-CG 4.33Å; I124-P237 HydrophobicContact CD1-CG 4.23Å; I124-P237 HydrophobicContact CG1-CG 4.4Å; I124-Y238 PolarHBondContact N-O 3.27Å; I124-W239 HydrophobicContact CG2-CB 4.31Å; I124-V249 HydrophobicContact CG2-CG1 3.86Å; I124-L254 HydrophobicContact CD1-CD2 4.01Å; I124-L254 HydrophobicContact CG1-CD2 4.07Å; I124-M255 HydrophobicContact CD1-CE 3.24Å; I124-L391 HydrophobicContact CB-CD2 4.37Å; I124-L391 HydrophobicContact CD1-CD1 4.06Å; I124-L391 HydrophobicContact CD1-CD2 3.85Å; I124-L391 HydrophobicContact CG2-CD1 4.13Å; I124-L391 HydrophobicContact CG2-CD2 4.43Å
125M96.6Very high96.3Very high79 Ų7953.3 Ų53.339%0.38927%0.274SS..G310 helixtrans-68.4-17.9179.5-58.5-56.3-68.700113.3N123 E248 V249 L254N123-M125 PolarHBondContact O-N 3.23Å; N123-M125 VanDerWaalsContact O-N 3.12Å; N123-M125 WeakPolarHBondContact OD1-CB 3.34Å; N123-M125 PolarHBondContact OD1-N 2.76Å; M125-E248 HydrophobicContact CE-CB 3.96Å; M125-E248 HydrophobicContact SD-CB 4.5Å; M125-V249 HydrophobicContact SD-CG1 3.72Å; M125-L254 HydrophobicContact SD-CD1 4.02Å
126T94.6Very high96.4Very high93 Ų9348.3 Ų48.357%0.57125%0.251SS*.G310 helixtrans-110.6-4.7-177.764.20000113.6N123 I124N123-T126 HydrophobicContact CB-CG2 4.32Å; N123-T126 PolarHBondContact O-N 2.61Å; N123-T126 PolarHBondContact O-OG1 3.43Å; I124-T126 PolarHBondContact O-N 3.1Å
127M95.1Very high96.5Very high26 Ų2646.6 Ų46.613%0.12826%0.255CS..SBendtrans-72155.3176.7-73167.766.400110.9R122 N123 I124 E131 Q132 P237R122-M127 HydrophobicContact CB-CG 3.87Å; R122-M127 HydrophobicContact CB-SD 4.09Å; N123-M127 PolarHBondContact O-N 2.54Å; I124-M127 HydrophobicContact CB-SD 4.44Å; I124-M127 HydrophobicContact CG1-SD 4.45Å; I124-M127 PolarHBondContact O-N 3.27Å; M127-E131 HydrophobicContact CB-CB 4.2Å; M127-E131 HydrophobicContact CE-CB 3.57Å; M127-Q132 HydrophobicContact CB-CG 4.02Å; M127-Q132 PolarHBondContact O-NE2 3.13Å; M127-P237 HydrophobicContact CE-CB 4.34Å; M127-P237 HydrophobicContact SD-CB 3.5Å; M127-P237 VanDerWaalsContact SD-CB 3.5Å; M127-P237 HydrophobicContact SD-CG 4.16Å
128S95.8Very high96.8Very high53 Ų5345.1 Ų45.137%0.37125%0.249SC..  trans-65.1155.8172.466.60000111.1A130 E131 Q132S128-A130 PolarHBondContact O-N 3.04Å; S128-E131 WeakPolarHBondContact CB-OE2 3.31Å; S128-E131 PolarHBondContact N-OE2 2.92Å; S128-E131 PolarHBondContact O-N 3.05Å; S128-E131 VanDerWaalsContact O-N 3.12Å; S128-E131 VanDerWaalsContact OG-CG 3.24Å; S128-E131 WeakPolarHBondContact OG-CG 3.41Å; S128-E131 PolarHBondContact OG-N 3.32Å; S128-E131 PolarHBondContact OG-OE2 2.87Å; S128-Q132 WeakPolarHBondContact O-CG 3.43Å; S128-Q132 PolarHBondContact O-N 2.66Å
129T95.4Very high97.1Very high90 Ų9042.3 Ų42.355%0.55224%0.236SC*.Hα-helixtrans-57.1-35.5176-53.30000112.2Q132 Q133T129-Q132 PolarHBondContact O-N 3.47Å; T129-Q133 HydrophobicContact CG2-CG 4.39Å; T129-Q133 WeakPolarHBondContact O-CB 3.45Å; T129-Q133 VanDerWaalsContact O-CG 3.25Å; T129-Q133 WeakPolarHBondContact O-CG 3.1Å; T129-Q133 PolarHBondContact O-N 3.47Å
130A96.3Very high97.3Very high65 Ų6544 Ų4454%0.53725%0.245SC..Hα-helixtrans-65.6-43.6176.900000112S128 Q133 K134S128-A130 PolarHBondContact O-N 3.04Å; A130-Q133 PolarHBondContact O-N 2.94Å; A130-K134 WeakPolarHBondContact O-CB 3.48Å; A130-K134 PolarHBondContact O-N 2.8Å
131E96.8Very high97.5Very high36 Ų3645.9 Ų45.917%0.16825%0.253CS..Hα-helixtrans-67.3-39.5176.3-69.1168.2107.500112.1R122 M127 S128 K134 F135R122-E131 IonicContact CZ-OE1 3.05Å; R122-E131 VanDerWaalsContact NH1-CD 3.28Å; R122-E131 IonicContact NH1-OE1 3.84Å; R122-E131 PolarHBondContact NH1-OE1 2.91Å; R122-E131 IonicContact NH1-OE2 2.78Å; R122-E131 PolarHBondContact NH1-OE2 2.89Å; R122-E131 VanDerWaalsContact NH1-OE2 3.1Å; M127-E131 HydrophobicContact CB-CB 4.2Å; M127-E131 HydrophobicContact CE-CB 3.57Å; S128-E131 WeakPolarHBondContact CB-OE2 3.31Å; S128-E131 PolarHBondContact N-OE2 2.92Å; S128-E131 PolarHBondContact O-N 3.05Å; S128-E131 VanDerWaalsContact O-N 3.12Å; S128-E131 VanDerWaalsContact OG-CG 3.24Å; S128-E131 WeakPolarHBondContact OG-CG 3.41Å; S128-E131 PolarHBondContact OG-N 3.32Å; S128-E131 PolarHBondContact OG-OE2 2.87Å; E131-K134 PolarHBondContact O-N 3.05Å; E131-F135 PolarHBondContact O-N 2.88Å
132Q98.1Very high97.5Very high25 Ų2545.9 Ų45.912%0.11725%0.253CS..Hα-helixtrans-60.6-48.6174.3-71.1171.9-11.800111.1I124 M127 S128 T129 K134 F135 I136 L254I124-Q132 HydrophobicContact CG1-CG 4.25Å; I124-Q132 PolarHBondContact O-NE2 2.9Å; M127-Q132 HydrophobicContact CB-CG 4.02Å; M127-Q132 PolarHBondContact O-NE2 3.13Å; S128-Q132 WeakPolarHBondContact O-CG 3.43Å; S128-Q132 PolarHBondContact O-N 2.66Å; T129-Q132 PolarHBondContact O-N 3.47Å; Q132-K134 VanDerWaalsContact C-N 3.33Å; Q132-K134 PolarHBondContact O-N 2.98Å; Q132-F135 PolarHBondContact O-N 2.63Å; Q132-I136 WeakPolarHBondContact O-CD1 3.38Å; Q132-I136 WeakPolarHBondContact O-CG1 3.48Å; Q132-I136 PolarHBondContact O-N 2.76Å; Q132-I136 VanDerWaalsContact O-N 3.09Å; Q132-L254 HydrophobicContact CB-CD2 3.93Å; Q132-L254 HydrophobicContact CG-CD2 3.8Å
133Q97.6Very high97.6Very high112 Ų11245.1 Ų45.152%0.52325%0.251SS..Hα-helixtrans-63.7-37.9176.7-74.5175.4-1100112.2T129 A130 I136 S137T129-Q133 HydrophobicContact CG2-CG 4.39Å; T129-Q133 WeakPolarHBondContact O-CB 3.45Å; T129-Q133 VanDerWaalsContact O-CG 3.25Å; T129-Q133 WeakPolarHBondContact O-CG 3.1Å; T129-Q133 PolarHBondContact O-N 3.47Å; A130-Q133 PolarHBondContact O-N 2.94Å; Q133-I136 PolarHBondContact O-N 2.82Å; Q133-S137 VanDerWaalsContact O-CB 3.28Å; Q133-S137 WeakPolarHBondContact O-CB 3.16Å; Q133-S137 PolarHBondContact O-N 2.67Å; Q133-S137 PolarHBondContact O-OG 3.38Å
134K98.2Very high97.6Very high76 Ų7649.6 Ų49.633%0.3328%0.275SS..Hα-helixtrans-59.2-48.8174-174.2179.372.4163.30110.9A130 E131 Q132 I136 S137 Y138 D231A130-K134 WeakPolarHBondContact O-CB 3.48Å; A130-K134 PolarHBondContact O-N 2.8Å; E131-K134 PolarHBondContact O-N 3.05Å; Q132-K134 VanDerWaalsContact C-N 3.33Å; Q132-K134 PolarHBondContact O-N 2.98Å; K134-I136 PolarHBondContact O-N 3.29Å; K134-S137 PolarHBondContact O-N 3.12Å; K134-Y138 HydrophobicContact CD-CE2 3.99Å; K134-Y138 HydrophobicContact CG-CD1 4.29Å; K134-Y138 HydrophobicContact CG-CD2 4.25Å; K134-Y138 HydrophobicContact CG-CE1 3.91Å; K134-Y138 HydrophobicContact CG-CE2 3.84Å; K134-Y138 HydrophobicContact CG-CG 4.46Å; K134-Y138 WeakPolarHBondContact O-CB 3.2Å; K134-Y138 WeakPolarHBondContact O-CD1 3.25Å; K134-Y138 PolarHBondContact O-N 3.48Å; K134-D231 IonicContact NZ-OD2 3.88Å; K134-D231 PolarHBondContact NZ-OD2 3.18Å
135F98.6Very high97.6Very high2 Ų251.6 Ų51.61%0.00929%0.287CS..Hα-helixtrans-56.6-51.4177.5176.1-106.6000111.7I124 E131 Q132 S137 Y138 L139 F234 P237 M255 L390 L391I124-F135 HydrophobicContact CD1-CD1 4.13Å; I124-F135 HydrophobicContact CD1-CE1 4.39Å; E131-F135 PolarHBondContact O-N 2.88Å; Q132-F135 PolarHBondContact O-N 2.63Å; F135-S137 VanDerWaalsContact C-N 3.32Å; F135-S137 PolarHBondContact O-N 2.94Å; F135-Y138 PolarHBondContact O-N 3.04Å; F135-L139 HydrophobicContact CD1-CD1 4.31Å; F135-L139 HydrophobicContact CE1-CD1 3.58Å; F135-L139 HydrophobicContact CE1-CG 4.19Å; F135-L139 HydrophobicContact CE2-CD1 4.24Å; F135-L139 HydrophobicContact CE2-CD2 4.04Å; F135-L139 HydrophobicContact CE2-CG 4.16Å; F135-L139 HydrophobicContact CZ-CD1 3.56Å; F135-L139 HydrophobicContact CZ-CD2 4.12Å; F135-L139 HydrophobicContact CZ-CG 3.97Å; F135-L139 WeakPolarHBondContact O-CG 3.34Å; F135-L139 PolarHBondContact O-N 3.28Å; F135-F234 AromaticContact CD2-CE2 3.76Å; F135-F234 HydrophobicContact CD2-CE2 3.76Å; F135-F234 AromaticContact CD2-CZ 3.79Å; F135-F234 HydrophobicContact CD2-CZ 3.79Å; F135-F234 HydrophobicContact CE2-CE2 4.46Å; F135-F234 HydrophobicContact CE2-CZ 4.04Å; F135-P237 HydrophobicContact CD1-CG 4.18Å; F135-P237 HydrophobicContact CD2-CG 3.89Å; F135-P237 HydrophobicContact CE1-CG 4.25Å; F135-P237 HydrophobicContact CE2-CG 4Å; F135-P237 HydrophobicContact CG-CG 4Å; F135-P237 HydrophobicContact CZ-CG 4.15Å; F135-M255 HydrophobicContact CD1-CE 3.71Å; F135-M255 HydrophobicContact CE1-CE 3.46Å; F135-M255 VanDerWaalsContact CE1-CE 3.46Å; F135-M255 HydrophobicContact CE1-SD 4.32Å; F135-L390 HydrophobicContact CZ-CD1 4.3Å; F135-L391 HydrophobicContact CE1-CD2 4.01Å; F135-L391 HydrophobicContact CZ-CD2 4.13Å
136I98.6Very high97.6Very high18 Ų1852 Ų529%0.09229%0.29CS..Hα-helixtrans-60.4-42.9179.1-63.3159.1000111.2Q132 Q133 K134 Y138 L139 N140 A253 L254 M255 V271 F272Q132-I136 WeakPolarHBondContact O-CD1 3.38Å; Q132-I136 WeakPolarHBondContact O-CG1 3.48Å; Q132-I136 PolarHBondContact O-N 2.76Å; Q132-I136 VanDerWaalsContact O-N 3.09Å; Q133-I136 PolarHBondContact O-N 2.82Å; K134-I136 PolarHBondContact O-N 3.29Å; I136-Y138 VanDerWaalsContact C-N 3.33Å; I136-Y138 PolarHBondContact O-N 3.21Å; I136-L139 PolarHBondContact O-N 2.98Å; I136-N140 PolarHBondContact O-N 2.7Å; I136-A253 WeakPolarHBondContact CD1-O 3.41Å; I136-L254 WeakPolarHBondContact CD1-O 3.42Å; I136-M255 HydrophobicContact CG1-CE 4.49Å; I136-V271 HydrophobicContact CG2-CG2 3.7Å; I136-F272 HydrophobicContact CB-CZ 4.47Å; I136-F272 HydrophobicContact CG1-CE2 4.46Å; I136-F272 HydrophobicContact CG1-CZ 4.46Å; I136-F272 HydrophobicContact CG2-CE2 4Å; I136-F272 HydrophobicContact CG2-CZ 3.85Å
137S98.5Very high97.8Very high70 Ų7047.6 Ų47.649%0.4926%0.263SS..Hα-helixtrans-64-38.9178.8-58.80000111.8Q133 K134 F135 N140 L141Q133-S137 VanDerWaalsContact O-CB 3.28Å; Q133-S137 WeakPolarHBondContact O-CB 3.16Å; Q133-S137 PolarHBondContact O-N 2.67Å; Q133-S137 PolarHBondContact O-OG 3.38Å; K134-S137 PolarHBondContact O-N 3.12Å; F135-S137 VanDerWaalsContact C-N 3.32Å; F135-S137 PolarHBondContact O-N 2.94Å; S137-N140 PolarHBondContact O-N 3.32Å; S137-L141 WeakPolarHBondContact O-CB 3.28Å; S137-L141 PolarHBondContact O-N 2.99Å
138Y98.8Very high97.7Very high46 Ų4649.8 Ų49.818%0.1828%0.279CS..Hα-helixtrans-70.3-38.6177.9-74.25.3000112.2K134 F135 I136 N140 L141 A142 I225 T229 D231 F234K134-Y138 HydrophobicContact CD-CE2 3.99Å; K134-Y138 HydrophobicContact CG-CD1 4.29Å; K134-Y138 HydrophobicContact CG-CD2 4.25Å; K134-Y138 HydrophobicContact CG-CE1 3.91Å; K134-Y138 HydrophobicContact CG-CE2 3.84Å; K134-Y138 HydrophobicContact CG-CG 4.46Å; K134-Y138 WeakPolarHBondContact O-CB 3.2Å; K134-Y138 WeakPolarHBondContact O-CD1 3.25Å; K134-Y138 PolarHBondContact O-N 3.48Å; F135-Y138 PolarHBondContact O-N 3.04Å; I136-Y138 VanDerWaalsContact C-N 3.33Å; I136-Y138 PolarHBondContact O-N 3.21Å; Y138-N140 VanDerWaalsContact C-N 3.33Å; Y138-L141 PolarHBondContact O-N 3.27Å; Y138-A142 WeakPolarHBondContact O-CB 3.39Å; Y138-A142 PolarHBondContact O-N 2.88Å; Y138-I225 HydrophobicContact CD2-CG2 4.12Å; Y138-I225 HydrophobicContact CG-CG2 4.44Å; Y138-T229 HydrophobicContact CD1-CG2 3.64Å; Y138-T229 HydrophobicContact CD2-CG2 3.59Å; Y138-T229 HydrophobicContact CE1-CG2 3.82Å; Y138-T229 HydrophobicContact CE2-CG2 3.79Å; Y138-T229 HydrophobicContact CG-CG2 3.52Å; Y138-D231 HydrophobicContact CE2-CB 3.79Å; Y138-D231 VanDerWaalsContact OH-CB 3.26Å; Y138-D231 WeakPolarHBondContact OH-CB 3.39Å; Y138-D231 PolarHBondContact OH-OD2 3.23Å; Y138-F234 HydrophobicContact CD2-CB 4.48Å; Y138-F234 AromaticContact CD2-CD2 3.42Å; Y138-F234 HydrophobicContact CD2-CD2 3.42Å; Y138-F234 VanDerWaalsContact CD2-CD2 3.42Å; Y138-F234 AromaticContact CD2-CE2 3.72Å; Y138-F234 HydrophobicContact CD2-CE2 3.72Å; Y138-F234 HydrophobicContact CD2-CG 4.01Å; Y138-F234 HydrophobicContact CE2-CB 4.3Å; Y138-F234 AromaticContact CE2-CD2 3.87Å; Y138-F234 HydrophobicContact CE2-CD2 3.87Å; Y138-F234 HydrophobicContact CE2-CG 4.31Å
139L98.8Very high97.7Very high0 Ų048.9 Ų48.90%027%0.27CS..Hα-helixtrans-61.5-44.2171.6-64.9-167.1000111.2F135 I136 A142 K143 Y175 I225 F272 W275 P387 L390F135-L139 HydrophobicContact CD1-CD1 4.31Å; F135-L139 HydrophobicContact CE1-CD1 3.58Å; F135-L139 HydrophobicContact CE1-CG 4.19Å; F135-L139 HydrophobicContact CE2-CD1 4.24Å; F135-L139 HydrophobicContact CE2-CD2 4.04Å; F135-L139 HydrophobicContact CE2-CG 4.16Å; F135-L139 HydrophobicContact CZ-CD1 3.56Å; F135-L139 HydrophobicContact CZ-CD2 4.12Å; F135-L139 HydrophobicContact CZ-CG 3.97Å; F135-L139 WeakPolarHBondContact O-CG 3.34Å; F135-L139 PolarHBondContact O-N 3.28Å; I136-L139 PolarHBondContact O-N 2.98Å; L139-A142 PolarHBondContact O-N 2.81Å; L139-K143 WeakPolarHBondContact O-CB 3.28Å; L139-K143 PolarHBondContact O-N 3.28Å; L139-Y175 HydrophobicContact CD2-CD2 4.43Å; L139-Y175 HydrophobicContact CD2-CE2 4.27Å; L139-I225 HydrophobicContact CD2-CD1 3.92Å; L139-F272 HydrophobicContact CB-CE1 4.35Å; L139-F272 HydrophobicContact CD1-CE1 4.42Å; L139-F272 HydrophobicContact CD1-CZ 4.29Å; L139-W275 HydrophobicContact CB-CH2 4.14Å; L139-W275 HydrophobicContact CB-CZ2 4.34Å; L139-P387 HydrophobicContact CD1-CB 3.67Å; L139-L390 HydrophobicContact CD1-CD1 4.21Å; L139-L390 HydrophobicContact CD2-CD1 3.55Å
140N98.6Very high97.8Very high46 Ų4644.7 Ų44.725%0.24624%0.244CC..Hα-helixtrans-66.6-37.3177.6-166.258.5000112.3I136 S137 Y138 K143 N144 V271 W275I136-N140 PolarHBondContact O-N 2.7Å; S137-N140 PolarHBondContact O-N 3.32Å; Y138-N140 VanDerWaalsContact C-N 3.33Å; N140-K143 PolarHBondContact O-N 2.88Å; N140-N144 PolarHBondContact O-N 3.03Å; N140-N144 PolarHBondContact O-ND2 3.09Å; N140-N144 PolarHBondContact OD1-ND2 3.48Å; N140-V271 HydrophobicContact CB-CG2 4.28Å; N140-W275 PolarHBondContact OD1-NE1 3.44Å; N140-W275 VanDerWaalsContact OD1-NE1 3.08Å
141L98.7Very high97.7Very high71 Ų7141.6 Ų41.637%0.37222%0.219SC..Hα-helixtrans-60.9-48.1171.2-179.667.1000110.7S137 Y138 K143 N144 T145 I228 T229S137-L141 WeakPolarHBondContact O-CB 3.28Å; S137-L141 PolarHBondContact O-N 2.99Å; Y138-L141 PolarHBondContact O-N 3.27Å; L141-K143 VanDerWaalsContact C-N 3.31Å; L141-K143 PolarHBondContact O-N 2.91Å; L141-N144 CarbonylContact O-C 3.42Å; L141-N144 PolarHBondContact O-N 3.46Å; L141-T145 WeakPolarHBondContact CD1-OG1 3.41Å; L141-T145 VanDerWaalsContact O-CB 3.29Å; L141-T145 WeakPolarHBondContact O-CB 3.31Å; L141-T145 PolarHBondContact O-N 3.2Å; L141-T145 PolarHBondContact O-OG1 2.73Å; L141-I228 HydrophobicContact CG-CD1 4.47Å; L141-T229 HydrophobicContact CD2-CG2 3.89Å
142A98.7Very high97.8Very high0 Ų039.9 Ų39.90%021%0.211CC..Hα-helixtrans-59.2-40.617900000112.3Y138 L139 N144 T145 N173 T174 Y175 I225 I228Y138-A142 WeakPolarHBondContact O-CB 3.39Å; Y138-A142 PolarHBondContact O-N 2.88Å; L139-A142 PolarHBondContact O-N 2.81Å; A142-N144 PolarHBondContact O-N 3.39Å; A142-T145 PolarHBondContact O-N 2.83Å; A142-N173 PolarHBondContact O-OD1 3.28Å; A142-T174 HydrophobicContact CB-CG2 4.23Å; A142-T174 PolarHBondContact O-N 3.13Å; A142-Y175 PolarHBondContact O-N 3.35Å; A142-Y175 VanDerWaalsContact O-N 3.15Å; A142-I225 HydrophobicContact CB-CG1 4.27Å; A142-I228 HydrophobicContact CB-CD1 3.81Å
143K98.4Very high97.6Very high17 Ų1738.7 Ų38.77%0.07421%0.205CC..Hα-helixtrans-65.4-22.5176.2-172.363.2166.2172.50113.5L139 N140 L141 N173 Y175 D176 W275 K276L139-K143 WeakPolarHBondContact O-CB 3.28Å; L139-K143 PolarHBondContact O-N 3.28Å; N140-K143 PolarHBondContact O-N 2.88Å; L141-K143 VanDerWaalsContact C-N 3.31Å; L141-K143 PolarHBondContact O-N 2.91Å; K143-N173 WeakPolarHBondContact CA-OD1 3.37Å; K143-N173 WeakPolarHBondContact O-CB 2.94Å; K143-N173 PolarHBondContact O-ND2 3.19Å; K143-N173 PolarHBondContact O-OD1 3.27Å; K143-Y175 HydrophobicContact CB-CG 4.46Å; K143-Y175 HydrophobicContact CD-CD1 4.12Å; K143-Y175 HydrophobicContact CD-CG 4.26Å; K143-D176 IonicContact NZ-OD1 3.19Å; K143-D176 PolarHBondContact NZ-OD1 2.66Å; K143-D176 IonicContact NZ-OD2 3.66Å; K143-D176 PolarHBondContact NZ-OD2 2.9Å; K143-W275 HydrophobicContact CB-CD2 4.42Å; K143-W275 HydrophobicContact CB-CH2 4.05Å; K143-W275 HydrophobicContact CB-CZ2 3.57Å; K143-W275 HydrophobicContact CD-CD2 4.21Å; K143-W275 HydrophobicContact CD-CE3 4.2Å; K143-W275 HydrophobicContact CD-CZ3 4.41Å; K143-W275 HydrophobicContact CG-CD2 3.8Å; K143-W275 HydrophobicContact CG-CE3 4.25Å; K143-W275 HydrophobicContact CG-CG 4.19Å; K143-W275 HydrophobicContact CG-CH2 4.34Å; K143-W275 HydrophobicContact CG-CZ2 3.91Å; K143-K276 WeakPolarHBondContact CE-O 3.48Å; K143-K276 PolarHBondContact NZ-O 3.25Å
144N98.1Very high97.5Very high116 Ų11634.9 Ų34.962%0.6219%0.19SC*.Hα-helixtrans-1125.7-177.5-68.8-80.4000113.6N140 L141 A142N140-N144 PolarHBondContact O-N 3.03Å; N140-N144 PolarHBondContact O-ND2 3.09Å; N140-N144 PolarHBondContact OD1-ND2 3.48Å; L141-N144 CarbonylContact O-C 3.42Å; L141-N144 PolarHBondContact O-N 3.46Å; A142-N144 PolarHBondContact O-N 3.39Å
145T98.4Very high97.3Very high43 Ų4331.3 Ų31.326%0.26417%0.174SC..SBendtrans-117.9115.6-178.3-55.40000109.7L141 A142 N147 N173 T174 I228L141-T145 WeakPolarHBondContact CD1-OG1 3.41Å; L141-T145 VanDerWaalsContact O-CB 3.29Å; L141-T145 WeakPolarHBondContact O-CB 3.31Å; L141-T145 PolarHBondContact O-N 3.2Å; L141-T145 PolarHBondContact O-OG1 2.73Å; A142-T145 PolarHBondContact O-N 2.83Å; T145-N147 PolarHBondContact O-N 3.39Å; T145-N173 CarbonylContact O-C 3.43Å; T145-N173 WeakPolarHBondContact O-CA 3.47Å; T145-N173 WeakPolarHBondContact O-CB 3.16Å; T145-T174 PolarHBondContact O-N 3.28Å; T145-T174 PolarHBondContact O-OG1 3.11Å; T145-I228 HydrophobicContact CG2-CG2 4.39Å
146I98.1Very high97.1Very high87 Ų8732.4 Ų32.445%0.44618%0.181SC..BIsolated β-bridgetrans-54.4128.1171.7-61.1-56.3000109.1D171 I172I146-D171 HydrophobicContact CD1-CB 4.48Å; I146-D171 HydrophobicContact CG2-CB 4.33Å; I146-I172 WeakPolarHBondContact CA-O 3.42Å
147N97.4Very high96.8Very high0 Ų032.5 Ų32.50%018%0.18CC..  trans-67.2125.5-176.6-177.1-72.5000109.8R23 T145 D149 Y150 I172 T174 L177 E224R23-N147 PolarHBondContact NE-O 2.94Å; R23-N147 PolarHBondContact NH2-O 3.2Å; T145-N147 PolarHBondContact O-N 3.39Å; N147-D149 VanDerWaalsContact C-N 3.27Å; N147-D149 PolarHBondContact O-N 3.34Å; N147-D149 PolarHBondContact OD1-N 2.72Å; N147-Y150 WeakPolarHBondContact CB-O 3.15Å; N147-Y150 VanDerWaalsContact O-O 3.12Å; N147-Y150 PolarHBondContact OD1-N 3.06Å; N147-Y150 PolarHBondContact OD1-O 3.33Å; N147-I172 PolarHBondContact N-O 3.43Å; N147-T174 WeakPolarHBondContact CA-OG1 3.12Å; N147-L177 HydrophobicContact CB-CD2 4.38Å; N147-E224 PolarHBondContact ND2-OE2 3.19Å
148P94.6Very high96.6Very high72 Ų7233.2 Ų33.247%0.46819%0.19SC..SBendtrans-73.2-16.5-171.929.3-35.9000114.3R23 I228R23-P148 WeakPolarHBondContact CD-O 3.39Å; R23-P148 PolarHBondContact NE-O 3.16Å; P148-I228 HydrophobicContact CG-CG2 4.48Å
149D94.9Very high96.3Very high34 Ų3434.7 Ų34.718%0.18220%0.199CC..SBendtrans-114.1-34.8-170-68-54.9000112.9P22 R23 F99 N147 K227P22-D149 CarbonylContact C-O 3.44Å; P22-D149 WeakPolarHBondContact CA-O 3.38Å; R23-D149 PolarHBondContact N-O 2.79Å; F99-D149 HydrophobicContact CE1-CB 3.77Å; F99-D149 HydrophobicContact CZ-CB 4.44Å; N147-D149 VanDerWaalsContact C-N 3.27Å; N147-D149 PolarHBondContact O-N 3.34Å; N147-D149 PolarHBondContact OD1-N 2.72Å; D149-K227 WeakPolarHBondContact OD2-CE 3.21Å; D149-K227 IonicContact OD2-NZ 3.38Å; D149-K227 PolarHBondContact OD2-NZ 3.02Å
150Y96.6Very high96.1Very high2 Ų234.7 Ų34.71%0.00820%0.199CC..  trans-128.9166.3-172-57.5-78.5000110.7S19 Q20 P22 F99 N147 L177 H220 L433S19-Y150 CarbonylContact O-C 3.59Å; Q20-Y150 VanDerWaalsContact O-CD1 3.29Å; Q20-Y150 WeakPolarHBondContact O-CD1 3.42Å; P22-Y150 HydrophobicContact CG-CE1 4.07Å; F99-Y150 HydrophobicContact CD1-CE1 4.35Å; F99-Y150 HydrophobicContact CD1-CE2 4.47Å; F99-Y150 AromaticContact CD1-CZ 3.93Å; N147-Y150 WeakPolarHBondContact CB-O 3.15Å; N147-Y150 VanDerWaalsContact O-O 3.12Å; N147-Y150 PolarHBondContact OD1-N 3.06Å; N147-Y150 PolarHBondContact OD1-O 3.33Å; Y150-L177 HydrophobicContact CD2-CD2 4.21Å; Y150-L177 HydrophobicContact CG-CD2 4.23Å; Y150-H220 AromaticContact CE2-CE1 3.57Å; Y150-H220 AromaticContact CE2-NE2 3.82Å; Y150-H220 AromaticContact CZ-CE1 3.76Å; Y150-H220 AromaticContact CZ-NE2 3.97Å; Y150-L433 WeakPolarHBondContact CE1-O 3.28Å; Y150-L433 VanDerWaalsContact CZ-O 3.32Å; Y150-L433 PolarHBondContact OH-O 3.26Å
151V96.2Very high95.8Very high0 Ų033.5 Ų33.50%020%0.197CC..  trans-160.5-155.1-164-1230000108S18 S19 Q20 R23 S170 D171 L177S18-V151 VanDerWaalsContact C-CG1 3.42Å; S18-V151 VanDerWaalsContact CB-CG2 3.49Å; S18-V151 WeakPolarHBondContact O-CB 3.48Å; S18-V151 WeakPolarHBondContact O-CG1 3.39Å; S19-V151 VanDerWaalsContact C-N 3.29Å; S19-V151 CarbonylContact C-O 3.58Å; S19-V151 VanDerWaalsContact CA-CG2 3.46Å; S19-V151 CarbonylContact O-C 3.58Å; S19-V151 VanDerWaalsContact O-C 3.31Å; S19-V151 WeakPolarHBondContact O-CA 3.45Å; S19-V151 WeakPolarHBondContact O-CB 3.42Å; S19-V151 WeakPolarHBondContact O-CG2 3.34Å; S19-V151 PolarHBondContact O-N 2.93Å; Q20-V151 WeakPolarHBondContact CA-O 3.41Å; Q20-V151 WeakPolarHBondContact CB-O 3.34Å; Q20-V151 PolarHBondContact N-O 3.35Å; R23-V151 HydrophobicContact CB-CG2 4.38Å; R23-V151 HydrophobicContact CG-CG2 3.2Å; V151-S170 WeakPolarHBondContact CG1-O 3.46Å; V151-D171 HydrophobicContact CG1-CB 4.35Å; V151-D171 WeakPolarHBondContact CG1-OD1 3.49Å; V151-L177 VanDerWaalsContact O-CD1 3.28Å; V151-L177 WeakPolarHBondContact O-CD1 3.47Å
152I97.1Very high95.2Very high0 Ų038.3 Ų38.30%022%0.218CC..EExtended strand (participates in β ladder)trans-139.4158.7173.559.5157.1000116T154 F169 S170 I172 L177 W180 T294I152-T154 HydrophobicContact CD1-CG2 4.18Å; I152-T154 HydrophobicContact CG1-CG2 4.42Å; I152-F169 CarbonylContact O-C 3.37Å; I152-F169 VanDerWaalsContact O-CA 3.22Å; I152-F169 WeakPolarHBondContact O-CA 3.36Å; I152-S170 WeakPolarHBondContact CG1-O 3.46Å; I152-S170 PolarHBondContact N-O 3.43Å; I152-S170 PolarHBondContact O-N 3.41Å; I152-I172 HydrophobicContact CB-CD1 4.44Å; I152-I172 HydrophobicContact CD1-CD1 4.02Å; I152-I172 HydrophobicContact CG1-CB 4.46Å; I152-I172 HydrophobicContact CG1-CD1 4.16Å; I152-I172 HydrophobicContact CG2-CB 4.23Å; I152-I172 HydrophobicContact CG2-CD1 3.47Å; I152-I172 VanDerWaalsContact CG2-CD1 3.47Å; I152-I172 HydrophobicContact CG2-CG1 4.46Å; I152-I172 HydrophobicContact CG2-CG2 4.08Å; I152-L177 HydrophobicContact CG2-CD1 4.34Å; I152-W180 HydrophobicContact CB-CD2 3.81Å; I152-W180 HydrophobicContact CB-CE3 4.32Å; I152-W180 HydrophobicContact CB-CG 4Å; I152-W180 HydrophobicContact CB-CZ2 4.4Å; I152-W180 VanDerWaalsContact CD1-CD1 3.41Å; I152-W180 HydrophobicContact CD1-CG 4.04Å; I152-W180 HydrophobicContact CG2-CB 3.76Å; I152-W180 HydrophobicContact CG2-CD2 3.47Å; I152-W180 VanDerWaalsContact CG2-CD2 3.47Å; I152-W180 HydrophobicContact CG2-CE3 3.81Å; I152-W180 HydrophobicContact CG2-CG 3.44Å; I152-W180 VanDerWaalsContact CG2-CG 3.44Å; I152-T294 HydrophobicContact CD1-CG2 3.61Å; I152-T294 HydrophobicContact CG1-CG2 4.04Å
153S95.4Very high94.6Very high1 Ų142.3 Ų42.31%0.00724%0.239CC..EExtended strand (participates in β ladder)trans-81.3134.1163.6-167.90000110.7A155 M160 W180S153-A155 PolarHBondContact OG-O 2.72Å; S153-M160 WeakPolarHBondContact OG-CE 3.44Å; S153-W180 WeakPolarHBondContact O-CZ2 3.05Å; S153-W180 PolarHBondContact O-NE1 3.22Å
154T94.6Very high94.2Very high32 Ų3241.5 Ų41.520%0.19624%0.236CC..  trans-110.25.6175.760.50000112.9I152 M168 N293I152-T154 HydrophobicContact CD1-CG2 4.18Å; I152-T154 HydrophobicContact CG1-CG2 4.42Å; T154-M168 PolarHBondContact N-O 2.73Å; T154-M168 PolarHBondContact OG1-O 3Å; T154-N293 HydrophobicContact CG2-CB 4.05Å
155A93.9Very high93.9Very high1 Ų141.8 Ų41.81%0.00823%0.233CC..SBendtrans-149.8165.4178.400000111.4S153 E159 M168 L291S153-A155 PolarHBondContact OG-O 2.72Å; A155-E159 HydrophobicContact CB-CB 3.89Å; A155-M168 HydrophobicContact CB-CB 3.68Å; A155-M168 HydrophobicContact CB-CE 3.73Å; A155-M168 HydrophobicContact CB-CG 4.15Å; A155-M168 HydrophobicContact CB-SD 3.41Å; A155-M168 WeakPolarHBondContact CB-SD 3.29Å; A155-L291 VanDerWaalsContact C-CD1 3.45Å; A155-L291 WeakPolarHBondContact O-CD1 3.28Å
156T94.4Very high93.7Very high24 Ų2443.9 Ų43.915%0.14724%0.243CC..  trans-69.4161.5170.8630000111.2D77 A158 E159 M160 F190D77-T156 VanDerWaalsContact OD2-CA 3.27Å; D77-T156 WeakPolarHBondContact OD2-CA 3.11Å; D77-T156 WeakPolarHBondContact OD2-CB 3.25Å; T156-A158 PolarHBondContact O-N 3.48Å; T156-E159 WeakPolarHBondContact CB-OE2 3.36Å; T156-E159 PolarHBondContact N-OE2 3.01Å; T156-E159 PolarHBondContact O-N 3.26Å; T156-E159 WeakPolarHBondContact OG1-CG 3.48Å; T156-E159 PolarHBondContact OG1-N 3.04Å; T156-E159 PolarHBondContact OG1-OE2 3.24Å; T156-M160 PolarHBondContact O-N 3.46Å; T156-F190 HydrophobicContact CG2-CD2 4.17Å; T156-F190 HydrophobicContact CG2-CE2 4.36Å
157R93.8Very high93.4Very high20 Ų2041.8 Ų41.88%0.07524%0.235CC..THydrogen-bonded Turntrans-60.5-34.9175.6-178.461.2-169.976-4.4111.5D77 A84 F85 E159 M160 G161 E162D77-R157 WeakPolarHBondContact OD1-CB 3.25Å; D77-R157 PolarHBondContact OD2-N 2.89Å; A84-R157 WeakPolarHBondContact O-CD 3.4Å; A84-R157 WeakPolarHBondContact O-CG 3.48Å; A84-R157 PolarHBondContact O-NE 3.49Å; F85-R157 HydrophobicContact CE1-CB 4.05Å; F85-R157 HydrophobicContact CZ-CB 4.13Å; R157-E159 VanDerWaalsContact C-N 3.35Å; R157-M160 PolarHBondContact O-N 2.75Å; R157-G161 PolarHBondContact NH1-O 2.93Å; R157-E162 PolarHBondContact NH2-O 2.84Å
158A92.8Very high93.3Very high85 Ų8544.5 Ų44.570%0.70225%0.248SC*.THydrogen-bonded Turntrans-61.1-42.5178.100000112T156 M160 G161T156-A158 PolarHBondContact O-N 3.48Å; A158-M160 PolarHBondContact O-N 2.84Å; A158-G161 PolarHBondContact O-N 3.12Å
159E93.8Very high93.3Very high78 Ų7841.8 Ų41.836%0.36423%0.229SC..THydrogen-bonded Turntrans-68.1-22.1178.6-70.8169.197.200113.7A155 T156 R157 G161 M168A155-E159 HydrophobicContact CB-CB 3.89Å; T156-E159 WeakPolarHBondContact CB-OE2 3.36Å; T156-E159 PolarHBondContact N-OE2 3.01Å; T156-E159 PolarHBondContact O-N 3.26Å; T156-E159 WeakPolarHBondContact OG1-CG 3.48Å; T156-E159 PolarHBondContact OG1-N 3.04Å; T156-E159 PolarHBondContact OG1-OE2 3.24Å; R157-E159 VanDerWaalsContact C-N 3.35Å; E159-G161 PolarHBondContact O-N 2.91Å; E159-M168 HydrophobicContact CB-SD 4.31Å
160M94.4Very high93.3Very high0 Ų041.8 Ų41.80%023%0.232CC..THydrogen-bonded Turntrans-77.3-3.1177.1-61.7-177.5-171.600113.9L31 F85 S153 T156 R157 A158 G164 E165 N166 M168 F169L31-M160 HydrophobicContact CD1-CB 4.24Å; L31-M160 HydrophobicContact CD1-SD 3.66Å; L31-M160 HydrophobicContact CD2-SD 4.38Å; F85-M160 HydrophobicContact CE1-CE 4.44Å; F85-M160 HydrophobicContact CE1-SD 4.41Å; S153-M160 WeakPolarHBondContact OG-CE 3.44Å; T156-M160 PolarHBondContact O-N 3.46Å; R157-M160 PolarHBondContact O-N 2.75Å; A158-M160 PolarHBondContact O-N 2.84Å; M160-G164 CarbonylContact O-C 3.31Å; M160-G164 VanDerWaalsContact O-CA 3.27Å; M160-G164 WeakPolarHBondContact O-CA 3.27Å; M160-E165 PolarHBondContact O-N 3.14Å; M160-N166 VanDerWaalsContact CA-O 3.25Å; M160-N166 WeakPolarHBondContact CA-O 3.4Å; M160-N166 WeakPolarHBondContact CB-O 3.26Å; M160-N166 PolarHBondContact O-N 3.25Å; M160-N166 VanDerWaalsContact O-N 3.09Å; M160-M168 HydrophobicContact CE-CB 4.12Å; M160-M168 WeakPolarHBondContact CE-O 3.49Å; M160-M168 HydrophobicContact CG-CB 4.22Å; M160-F169 HydrophobicContact CE-CD1 4.1Å; M160-F169 HydrophobicContact CE-CE1 3.61Å; M160-F169 HydrophobicContact CE-CZ 4Å; M160-F169 HydrophobicContact SD-CE1 4.12Å; M160-F169 HydrophobicContact SD-CE2 4.46Å; M160-F169 HydrophobicContact SD-CZ 3.88Å
161G91.4Very high93.3Very high20 Ų2045 Ų4521%0.20625%0.249CC..  trans79.5149.2-177.900000112.7R157 A158 E159 N163 G164 E165R157-G161 PolarHBondContact NH1-O 2.93Å; A158-G161 PolarHBondContact O-N 3.12Å; E159-G161 PolarHBondContact O-N 2.91Å; G161-N163 PolarHBondContact O-N 2.78Å; G161-N163 VanDerWaalsContact O-N 3.08Å; G161-G164 PolarHBondContact O-N 2.04Å; G161-E165 WeakPolarHBondContact CA-OE2 3.33Å
162E86.2Confident93.4Very high172 Ų17245.1 Ų45.180%0.80425%0.25SC*.THydrogen-bonded Turntrans-53.3-38.2-172-68.8-176173.800113R157R157-E162 PolarHBondContact NH2-O 2.84Å
163N87.2Confident93.4Very high85 Ų8546.2 Ų46.246%0.45526%0.256SS..THydrogen-bonded Turntrans-100.211.2179.8-53.3-63.8000113.7R32 G161 E165R32-N163 WeakPolarHBondContact CA-O 3.35Å; R32-N163 VanDerWaalsContact CB-O 3.25Å; R32-N163 WeakPolarHBondContact CB-O 3.33Å; R32-N163 HydrophobicContact CG-CB 4.25Å; G161-N163 PolarHBondContact O-N 2.78Å; G161-N163 VanDerWaalsContact O-N 3.08Å; N163-E165 HydrophobicContact CB-CG 4.47Å; N163-E165 WeakPolarHBondContact CB-OE1 3.42Å; N163-E165 PolarHBondContact ND2-OE1 3.17Å
164G89.3Confident93.5Very high0 Ų046.2 Ų46.20%026%0.255CS..  trans70.432.8-176.400000113.1S28 M160 G161 N166S28-G164 WeakPolarHBondContact CA-O 3.35Å; S28-G164 WeakPolarHBondContact CB-O 3.04Å; S28-G164 PolarHBondContact OG-O 3.2Å; M160-G164 CarbonylContact O-C 3.31Å; M160-G164 VanDerWaalsContact O-CA 3.27Å; M160-G164 WeakPolarHBondContact O-CA 3.27Å; G161-G164 PolarHBondContact O-N 2.04Å; G164-N166 PolarHBondContact O-N 2.68Å
165E91.9Very high93.7Very high122 Ų12244.7 Ų44.757%0.5725%0.246SC*.SBendtrans-63.2-23179-59100.8174.500112.4M160 G161 N163M160-E165 PolarHBondContact O-N 3.14Å; G161-E165 WeakPolarHBondContact CA-OE2 3.33Å; N163-E165 HydrophobicContact CB-CG 4.47Å; N163-E165 WeakPolarHBondContact CB-OE1 3.42Å; N163-E165 PolarHBondContact ND2-OE1 3.17Å
166N93.3Very high94Very high87 Ų8745.1 Ų45.147%0.46525%0.248SC..SBendtrans-126.676.6-178.7-174.238.4000111M160 G164 M168M160-N166 VanDerWaalsContact CA-O 3.25Å; M160-N166 WeakPolarHBondContact CA-O 3.4Å; M160-N166 WeakPolarHBondContact CB-O 3.26Å; M160-N166 PolarHBondContact O-N 3.25Å; M160-N166 VanDerWaalsContact O-N 3.09Å; G164-N166 PolarHBondContact O-N 2.68Å; N166-M168 PolarHBondContact ND2-SD 3.21Å; N166-M168 VanDerWaalsContact ND2-SD 3.36Å; N166-M168 WeakPolarHBondContact O-CG 3.48Å; N166-M168 PolarHBondContact O-N 2.7Å; N166-M168 VanDerWaalsContact O-N 3.15Å
167P93.3Very high94.2Very high43 Ų4344 Ų4428%0.27924%0.241SC..  trans-66.6114.417927.7-33000110.2S28 L31 F169S28-P167 VanDerWaalsContact OG-CD 3.31Å; S28-P167 WeakPolarHBondContact OG-CD 3.28Å; S28-P167 WeakPolarHBondContact OG-CG 3.36Å; L31-P167 HydrophobicContact CD1-CB 4.1Å; P167-F169 HydrophobicContact CB-CD2 3.83Å; P167-F169 HydrophobicContact CB-CE2 3.88Å
168M94.6Very high94.4Very high57 Ų5743 Ų4328%0.28124%0.238SC..  trans-10785.4-174.9-68.9-176.875.200111.3T154 A155 E159 M160 N166T154-M168 PolarHBondContact N-O 2.73Å; T154-M168 PolarHBondContact OG1-O 3Å; A155-M168 HydrophobicContact CB-CB 3.68Å; A155-M168 HydrophobicContact CB-CE 3.73Å; A155-M168 HydrophobicContact CB-CG 4.15Å; A155-M168 HydrophobicContact CB-SD 3.41Å; A155-M168 WeakPolarHBondContact CB-SD 3.29Å; E159-M168 HydrophobicContact CB-SD 4.31Å; M160-M168 HydrophobicContact CE-CB 4.12Å; M160-M168 WeakPolarHBondContact CE-O 3.49Å; M160-M168 HydrophobicContact CG-CB 4.22Å; N166-M168 PolarHBondContact ND2-SD 3.21Å; N166-M168 VanDerWaalsContact ND2-SD 3.36Å; N166-M168 WeakPolarHBondContact O-CG 3.48Å; N166-M168 PolarHBondContact O-N 2.7Å; N166-M168 VanDerWaalsContact O-N 3.15Å
169F94.4Very high94.7Very high15 Ų1539 Ų397%0.06620%0.204CC..EExtended strand (participates in β ladder)trans-133.7148.6-173.1-59.1-58.7000111.9S18 S19 F21 A26 L31 I152 M160 P167S18-F169 CarbonylContact O-C 3.5Å; S18-F169 WeakPolarHBondContact O-CB 3.45Å; S19-F169 VanDerWaalsContact CB-CB 3.45Å; S19-F169 VanDerWaalsContact CB-CE1 3.42Å; F21-F169 HydrophobicContact CD2-CD1 4.41Å; F21-F169 AromaticContact CD2-CE1 3.52Å; F21-F169 HydrophobicContact CD2-CE1 3.52Å; F21-F169 AromaticContact CD2-CZ 3.89Å; F21-F169 HydrophobicContact CD2-CZ 3.89Å; F21-F169 AromaticContact CE2-CE1 3.66Å; F21-F169 HydrophobicContact CE2-CE1 3.66Å; F21-F169 HydrophobicContact CE2-CZ 4.2Å; A26-F169 HydrophobicContact CB-CD2 4.22Å; A26-F169 VanDerWaalsContact O-CD2 3.28Å; A26-F169 WeakPolarHBondContact O-CD2 3.33Å; L31-F169 HydrophobicContact CD1-CE2 3.87Å; L31-F169 HydrophobicContact CD1-CZ 4.03Å; L31-F169 HydrophobicContact CD2-CZ 4.14Å; L31-F169 HydrophobicContact CG-CE2 4.31Å; L31-F169 HydrophobicContact CG-CZ 4.31Å; I152-F169 CarbonylContact O-C 3.37Å; I152-F169 VanDerWaalsContact O-CA 3.22Å; I152-F169 WeakPolarHBondContact O-CA 3.36Å; M160-F169 HydrophobicContact CE-CD1 4.1Å; M160-F169 HydrophobicContact CE-CE1 3.61Å; M160-F169 HydrophobicContact CE-CZ 4Å; M160-F169 HydrophobicContact SD-CE1 4.12Å; M160-F169 HydrophobicContact SD-CE2 4.46Å; M160-F169 HydrophobicContact SD-CZ 3.88Å; P167-F169 HydrophobicContact CB-CD2 3.83Å; P167-F169 HydrophobicContact CB-CE2 3.88Å
170S94.9Very high94.9Very high34 Ų3435.3 Ų35.324%0.23819%0.187CC..EExtended strand (participates in β ladder)trans-137.3141.2-176-169.70000113S18 V151 I152 T294S18-S170 CarbonylContact O-C 3.6Å; S18-S170 PolarHBondContact O-N 3.49Å; S18-S170 VanDerWaalsContact O-N 3.13Å; V151-S170 WeakPolarHBondContact CG1-O 3.46Å; I152-S170 WeakPolarHBondContact CG1-O 3.46Å; I152-S170 PolarHBondContact N-O 3.43Å; I152-S170 PolarHBondContact O-N 3.41Å; S170-T294 PolarHBondContact OG-OG1 3.45Å
171D96.6Very high95.1Very high69 Ų6935.3 Ų35.337%0.36919%0.187SC..  trans-53.4132.2166.6-82.8-37.1000112.4S18 R23 I146 V151 T294S18-D171 WeakPolarHBondContact CB-OD1 3.46Å; R23-D171 IonicContact CZ-OD1 3.72Å; R23-D171 VanDerWaalsContact CZ-OD1 3.26Å; R23-D171 IonicContact NH1-OD1 3.17Å; R23-D171 PolarHBondContact NH1-OD1 2.89Å; R23-D171 IonicContact NH2-OD1 3.43Å; R23-D171 PolarHBondContact NH2-OD1 2.95Å; I146-D171 HydrophobicContact CD1-CB 4.48Å; I146-D171 HydrophobicContact CG2-CB 4.33Å; V151-D171 HydrophobicContact CG1-CB 4.35Å; V151-D171 WeakPolarHBondContact CG1-OD1 3.49Å; D171-T294 WeakPolarHBondContact O-CG2 3.34Å
172I97.3Very high95.4Very high3 Ų334.4 Ų34.42%0.01518%0.177CC..  trans-134149.8176.4-156.5160.5000110.9I146 N147 I152 D176 L177 W180 I278 T294I146-I172 WeakPolarHBondContact CA-O 3.42Å; N147-I172 PolarHBondContact N-O 3.43Å; I152-I172 HydrophobicContact CB-CD1 4.44Å; I152-I172 HydrophobicContact CD1-CD1 4.02Å; I152-I172 HydrophobicContact CG1-CB 4.46Å; I152-I172 HydrophobicContact CG1-CD1 4.16Å; I152-I172 HydrophobicContact CG2-CB 4.23Å; I152-I172 HydrophobicContact CG2-CD1 3.47Å; I152-I172 VanDerWaalsContact CG2-CD1 3.47Å; I152-I172 HydrophobicContact CG2-CG1 4.46Å; I152-I172 HydrophobicContact CG2-CG2 4.08Å; I172-D176 HydrophobicContact CD1-CB 3.8Å; I172-D176 VanDerWaalsContact CD1-O 3.25Å; I172-D176 WeakPolarHBondContact CD1-O 3.5Å; I172-D176 HydrophobicContact CG1-CB 3.6Å; I172-L177 HydrophobicContact CG2-CB 3.84Å; I172-L177 HydrophobicContact CG2-CD1 3.91Å; I172-L177 HydrophobicContact CG2-CG 4.48Å; I172-W180 HydrophobicContact CD1-CB 3.98Å; I172-I278 HydrophobicContact CD1-CD1 4.09Å; I172-T294 HydrophobicContact CB-CG2 4.01Å; I172-T294 HydrophobicContact CD1-CG2 3.93Å; I172-T294 HydrophobicContact CG1-CG2 3.8Å
173N98.1Very high96Very high23 Ų2326.3 Ų26.312%0.12314%0.14CC..BIsolated β-bridgetrans-75.515917069.174.3000111.4A142 K143 T145 Y175 D176 L177A142-N173 PolarHBondContact O-OD1 3.28Å; K143-N173 WeakPolarHBondContact CA-OD1 3.37Å; K143-N173 WeakPolarHBondContact O-CB 2.94Å; K143-N173 PolarHBondContact O-ND2 3.19Å; K143-N173 PolarHBondContact O-OD1 3.27Å; T145-N173 CarbonylContact O-C 3.43Å; T145-N173 WeakPolarHBondContact O-CA 3.47Å; T145-N173 WeakPolarHBondContact O-CB 3.16Å; N173-Y175 VanDerWaalsContact C-N 3.26Å; N173-Y175 PolarHBondContact O-N 3.34Å; N173-Y175 PolarHBondContact OD1-N 2.86Å; N173-D176 VanDerWaalsContact ND2-CG 3.35Å; N173-D176 PolarHBondContact ND2-OD2 2.7Å; N173-D176 PolarHBondContact O-N 2.78Å; N173-D176 WeakPolarHBondContact OD1-CB 3.43Å; N173-D176 PolarHBondContact OD1-N 2.8Å; N173-L177 PolarHBondContact O-N 3.08Å
174T98.4Very high96.6Very high0 Ų022.4 Ų22.40%012%0.118CC..Hα-helixtrans-61.8-32.2-173.3-58.50000112.7A142 T145 N147 F178 E224 I228A142-T174 HydrophobicContact CB-CG2 4.23Å; A142-T174 PolarHBondContact O-N 3.13Å; T145-T174 PolarHBondContact O-N 3.28Å; T145-T174 PolarHBondContact O-OG1 3.11Å; N147-T174 WeakPolarHBondContact CA-OG1 3.12Å; T174-F178 WeakPolarHBondContact O-CD2 3.45Å; T174-E224 HydrophobicContact CG2-CB 3.86Å; T174-I228 HydrophobicContact CG2-CD1 3.98Å
175Y98.8Very high97Very high0 Ų022.4 Ų22.40%012%0.118CC..Hα-helixtrans-72.9-48176-169.3-78.3000111.2L139 A142 K143 N173 L177 F178 V179 W221 W275 A384 P387 L390L139-Y175 HydrophobicContact CD2-CD2 4.43Å; L139-Y175 HydrophobicContact CD2-CE2 4.27Å; A142-Y175 PolarHBondContact O-N 3.35Å; A142-Y175 VanDerWaalsContact O-N 3.15Å; K143-Y175 HydrophobicContact CB-CG 4.46Å; K143-Y175 HydrophobicContact CD-CD1 4.12Å; K143-Y175 HydrophobicContact CD-CG 4.26Å; N173-Y175 VanDerWaalsContact C-N 3.26Å; N173-Y175 PolarHBondContact O-N 3.34Å; N173-Y175 PolarHBondContact OD1-N 2.86Å; Y175-L177 VanDerWaalsContact C-N 3.27Å; Y175-L177 PolarHBondContact O-N 2.66Å; Y175-F178 PolarHBondContact O-N 2.96Å; Y175-F178 VanDerWaalsContact O-N 3.1Å; Y175-V179 HydrophobicContact CD1-CG2 3.9Å; Y175-V179 HydrophobicContact CE1-CG2 3.76Å; Y175-V179 PolarHBondContact O-N 2.9Å; Y175-W221 AromaticContact CD1-CZ2 3.99Å; Y175-W221 HydrophobicContact CD1-CZ2 3.99Å; Y175-W221 AromaticContact CD2-CZ2 3.61Å; Y175-W221 HydrophobicContact CD2-CZ2 3.61Å; Y175-W221 HydrophobicContact CE1-CH2 4.04Å; Y175-W221 AromaticContact CE1-CZ2 3.86Å; Y175-W221 HydrophobicContact CE1-CZ2 3.86Å; Y175-W221 HydrophobicContact CE2-CH2 4.14Å; Y175-W221 AromaticContact CE2-CZ2 3.48Å; Y175-W221 HydrophobicContact CE2-CZ2 3.48Å; Y175-W221 VanDerWaalsContact CE2-CZ2 3.48Å; Y175-W221 AromaticContact CG-CZ2 3.84Å; Y175-W221 HydrophobicContact CG-CZ2 3.84Å; Y175-W221 AromaticContact CZ-CH2 3.8Å; Y175-W221 AromaticContact CZ-CZ2 3.58Å; Y175-W275 HydrophobicContact CD1-CH2 4.31Å; Y175-W275 AromaticContact CD1-CZ3 3.92Å; Y175-W275 HydrophobicContact CD1-CZ3 3.92Å; Y175-W275 AromaticContact CD2-CH2 3.58Å; Y175-W275 HydrophobicContact CD2-CH2 3.58Å; Y175-W275 AromaticContact CD2-CZ3 3.95Å; Y175-W275 HydrophobicContact CD2-CZ3 3.95Å; Y175-W275 HydrophobicContact CE1-CE3 4.49Å; Y175-W275 HydrophobicContact CE1-CH2 4.26Å; Y175-W275 AromaticContact CE1-CZ3 3.61Å; Y175-W275 HydrophobicContact CE1-CZ3 3.61Å; Y175-W275 AromaticContact CE2-CH2 3.51Å; Y175-W275 HydrophobicContact CE2-CH2 3.51Å; Y175-W275 AromaticContact CE2-CZ3 3.63Å; Y175-W275 HydrophobicContact CE2-CZ3 3.63Å; Y175-W275 HydrophobicContact CG-CH2 4.01Å; Y175-W275 HydrophobicContact CG-CZ3 4.11Å; Y175-W275 AromaticContact CZ-CH2 3.89Å; Y175-W275 AromaticContact CZ-CZ3 3.47Å; Y175-W275 VanDerWaalsContact CZ-CZ3 3.47Å; Y175-A384 VanDerWaalsContact CE1-O 3.27Å; Y175-A384 WeakPolarHBondContact CE1-O 3.19Å; Y175-A384 PolarHBondContact OH-O 3.38Å; Y175-P387 VanDerWaalsContact OH-CA 3.28Å; Y175-P387 WeakPolarHBondContact OH-CA 3.41Å; Y175-L390 HydrophobicContact CE2-CD1 4.39Å
176D98.7Very high97.2Very high10 Ų1016.9 Ų16.95%0.0539%0.094CC..Hα-helixtrans-71.3-20.9-175.8-75.9-15.6000113.7K143 I172 N173 F178 V179 W180 I278K143-D176 IonicContact NZ-OD1 3.19Å; K143-D176 PolarHBondContact NZ-OD1 2.66Å; K143-D176 IonicContact NZ-OD2 3.66Å; K143-D176 PolarHBondContact NZ-OD2 2.9Å; I172-D176 HydrophobicContact CD1-CB 3.8Å; I172-D176 VanDerWaalsContact CD1-O 3.25Å; I172-D176 WeakPolarHBondContact CD1-O 3.5Å; I172-D176 HydrophobicContact CG1-CB 3.6Å; N173-D176 VanDerWaalsContact ND2-CG 3.35Å; N173-D176 PolarHBondContact ND2-OD2 2.7Å; N173-D176 PolarHBondContact O-N 2.78Å; N173-D176 WeakPolarHBondContact OD1-CB 3.43Å; N173-D176 PolarHBondContact OD1-N 2.8Å; D176-F178 PolarHBondContact O-N 3.13Å; D176-V179 PolarHBondContact O-N 3.43Å; D176-W180 WeakPolarHBondContact O-CB 3.32Å; D176-W180 PolarHBondContact O-N 3.01Å; D176-I278 HydrophobicContact CB-CD1 3.66Å; D176-I278 HydrophobicContact CB-CG1 4.42Å
177L98.5Very high97.4Very high0 Ų013.2 Ų13.20%07%0.073CC..Hα-helixtrans-49.8-48.5165.8-179.865.4000110.9N147 Y150 V151 I152 I172 N173 Y175 W180 I181N147-L177 HydrophobicContact CB-CD2 4.38Å; Y150-L177 HydrophobicContact CD2-CD2 4.21Å; Y150-L177 HydrophobicContact CG-CD2 4.23Å; V151-L177 VanDerWaalsContact O-CD1 3.28Å; V151-L177 WeakPolarHBondContact O-CD1 3.47Å; I152-L177 HydrophobicContact CG2-CD1 4.34Å; I172-L177 HydrophobicContact CG2-CB 3.84Å; I172-L177 HydrophobicContact CG2-CD1 3.91Å; I172-L177 HydrophobicContact CG2-CG 4.48Å; N173-L177 PolarHBondContact O-N 3.08Å; Y175-L177 VanDerWaalsContact C-N 3.27Å; Y175-L177 PolarHBondContact O-N 2.66Å; L177-W180 PolarHBondContact O-N 2.92Å; L177-I181 HydrophobicContact CD1-CD1 4.43Å; L177-I181 HydrophobicContact CG-CD1 4.07Å; L177-I181 VanDerWaalsContact O-CG1 3.28Å; L177-I181 WeakPolarHBondContact O-CG1 3.03Å; L177-I181 PolarHBondContact O-N 3.46Å
178F98.6Very high97.6Very high0 Ų011.9 Ų11.90%06%0.064CC..Hα-helixtrans-76.5-29.7-177.6-68.3-83.2000112.7T174 Y175 D176 W180 I181 H182 F217 H220 W221 E224T174-F178 WeakPolarHBondContact O-CD2 3.45Å; Y175-F178 PolarHBondContact O-N 2.96Å; Y175-F178 VanDerWaalsContact O-N 3.1Å; D176-F178 PolarHBondContact O-N 3.13Å; F178-W180 VanDerWaalsContact C-N 3.35Å; F178-I181 HydrophobicContact CD1-CD1 4.16Å; F178-I181 HydrophobicContact CE1-CD1 4.31Å; F178-H182 WeakPolarHBondContact O-CB 3.42Å; F178-H182 PolarHBondContact O-N 2.9Å; F178-H182 VanDerWaalsContact O-N 3.1Å; F178-F217 HydrophobicContact CB-CE2 3.84Å; F178-F217 HydrophobicContact CB-CZ 3.69Å; F178-F217 HydrophobicContact CD1-CD2 4.04Å; F178-F217 AromaticContact CD1-CE2 3.69Å; F178-F217 HydrophobicContact CD1-CE2 3.69Å; F178-F217 HydrophobicContact CD1-CZ 4.15Å; F178-F217 HydrophobicContact CG-CE2 4.27Å; F178-F217 HydrophobicContact CG-CZ 4.41Å; F178-F217 WeakPolarHBondContact O-CE2 3.41Å; F178-F217 VanDerWaalsContact O-CZ 3.27Å; F178-F217 WeakPolarHBondContact O-CZ 3.44Å; F178-H220 HydrophobicContact CE1-CB 3.96Å; F178-H220 AromaticContact CE1-CD2 3.43Å; F178-H220 VanDerWaalsContact CE1-CD2 3.43Å; F178-H220 WeakPolarHBondContact CE1-CD2 3.18Å; F178-H220 AromaticContact CE1-CG 3.9Å; F178-H220 HydrophobicContact CZ-CB 4.42Å; F178-H220 AromaticContact CZ-CD2 3.63Å; F178-W221 HydrophobicContact CB-CD2 3.42Å; F178-W221 VanDerWaalsContact CB-CD2 3.42Å; F178-W221 HydrophobicContact CB-CE3 3.36Å; F178-W221 HydrophobicContact CB-CG 4.14Å; F178-W221 HydrophobicContact CB-CH2 3.63Å; F178-W221 HydrophobicContact CB-CZ2 3.66Å; F178-W221 HydrophobicContact CB-CZ3 3.49Å; F178-W221 VanDerWaalsContact CB-CZ3 3.49Å; F178-W221 HydrophobicContact CD1-CB 3.68Å; F178-W221 AromaticContact CD1-CD2 3.88Å; F178-W221 HydrophobicContact CD1-CD2 3.88Å; F178-W221 HydrophobicContact CD1-CE3 4.02Å; F178-W221 AromaticContact CD1-CG 3.78Å; F178-W221 HydrophobicContact CD1-CG 3.78Å; F178-W221 HydrophobicContact CD2-CB 4.1Å; F178-W221 AromaticContact CD2-CD1 3.38Å; F178-W221 AromaticContact CD2-CD2 3.66Å; F178-W221 HydrophobicContact CD2-CD2 3.66Å; F178-W221 AromaticContact CD2-CE2 3.69Å; F178-W221 HydrophobicContact CD2-CE3 4.44Å; F178-W221 AromaticContact CD2-CG 3.49Å; F178-W221 HydrophobicContact CD2-CG 3.49Å; F178-W221 VanDerWaalsContact CD2-CG 3.49Å; F178-W221 HydrophobicContact CD2-CZ2 4.45Å; F178-W221 AromaticContact CD2-NE1 3.51Å; F178-W221 HydrophobicContact CE1-CB 3.64Å; F178-W221 HydrophobicContact CE1-CG 4.09Å; F178-W221 HydrophobicContact CE2-CB 4.09Å; F178-W221 AromaticContact CE2-CD1 3.64Å; F178-W221 HydrophobicContact CE2-CD2 4.48Å; F178-W221 AromaticContact CE2-CG 3.85Å; F178-W221 HydrophobicContact CE2-CG 3.85Å; F178-W221 HydrophobicContact CG-CB 3.94Å; F178-W221 AromaticContact CG-CD1 3.89Å; F178-W221 AromaticContact CG-CD2 3.35Å; F178-W221 HydrophobicContact CG-CD2 3.35Å; F178-W221 AromaticContact CG-CE2 3.72Å; F178-W221 AromaticContact CG-CE3 3.68Å; F178-W221 HydrophobicContact CG-CE3 3.68Å; F178-W221 AromaticContact CG-CG 3.49Å; F178-W221 HydrophobicContact CG-CG 3.49Å; F178-W221 VanDerWaalsContact CG-CG 3.49Å; F178-W221 HydrophobicContact CG-CZ2 4.32Å; F178-W221 HydrophobicContact CG-CZ3 4.31Å; F178-W221 HydrophobicContact CZ-CB 3.89Å; F178-W221 HydrophobicContact CZ-CG 4.16Å; F178-E224 HydrophobicContact CE2-CB 3.93Å; F178-E224 HydrophobicContact CE2-CG 4.01Å; F178-E224 HydrophobicContact CZ-CB 4.06Å; F178-E224 HydrophobicContact CZ-CG 3.73Å
179V98.8Very high97.8Very high0 Ų09.2 Ų9.20%05%0.05CC..Hα-helixtrans-60.6-47.6168.1-1790000110.4Y175 D176 H182 Y183 I278 A384 N385Y175-V179 HydrophobicContact CD1-CG2 3.9Å; Y175-V179 HydrophobicContact CE1-CG2 3.76Å; Y175-V179 PolarHBondContact O-N 2.9Å; D176-V179 PolarHBondContact O-N 3.43Å; V179-H182 PolarHBondContact O-N 3.21Å; V179-Y183 PolarHBondContact O-N 3.47Å; V179-I278 HydrophobicContact CB-CD1 4.29Å; V179-I278 HydrophobicContact CB-CG1 4.17Å; V179-I278 HydrophobicContact CG1-CD1 4.23Å; V179-I278 HydrophobicContact CG1-CG1 3.67Å; V179-A384 HydrophobicContact CG2-CB 4.24Å; V179-N385 VanDerWaalsContact CG1-ND2 3.29Å; V179-N385 WeakPolarHBondContact CG1-ND2 3.45Å
180W98.6Very high97.9Very high2 Ų29.5 Ų9.51%0.0085%0.052CC..Hα-helixtrans-66.6-39.6179.8-173.195.9000112.3Q20 I152 S153 I172 D176 L177 F178 H182 Y183 Y184 L291 C292 P431Q20-W180 HydrophobicContact CB-CE3 4.37Å; Q20-W180 HydrophobicContact CB-CH2 4.33Å; Q20-W180 HydrophobicContact CB-CZ3 3.87Å; Q20-W180 HydrophobicContact CG-CE3 4.3Å; Q20-W180 HydrophobicContact CG-CH2 4.42Å; Q20-W180 HydrophobicContact CG-CZ3 3.67Å; I152-W180 HydrophobicContact CB-CD2 3.81Å; I152-W180 HydrophobicContact CB-CE3 4.32Å; I152-W180 HydrophobicContact CB-CG 4Å; I152-W180 HydrophobicContact CB-CZ2 4.4Å; I152-W180 VanDerWaalsContact CD1-CD1 3.41Å; I152-W180 HydrophobicContact CD1-CG 4.04Å; I152-W180 HydrophobicContact CG2-CB 3.76Å; I152-W180 HydrophobicContact CG2-CD2 3.47Å; I152-W180 VanDerWaalsContact CG2-CD2 3.47Å; I152-W180 HydrophobicContact CG2-CE3 3.81Å; I152-W180 HydrophobicContact CG2-CG 3.44Å; I152-W180 VanDerWaalsContact CG2-CG 3.44Å; S153-W180 WeakPolarHBondContact O-CZ2 3.05Å; S153-W180 PolarHBondContact O-NE1 3.22Å; I172-W180 HydrophobicContact CD1-CB 3.98Å; D176-W180 WeakPolarHBondContact O-CB 3.32Å; D176-W180 PolarHBondContact O-N 3.01Å; L177-W180 PolarHBondContact O-N 2.92Å; F178-W180 VanDerWaalsContact C-N 3.35Å; W180-H182 VanDerWaalsContact C-N 3.33Å; W180-H182 PolarHBondContact O-N 2.99Å; W180-Y183 WeakPolarHBondContact O-CB 3.47Å; W180-Y183 PolarHBondContact O-N 3.08Å; W180-Y184 HydrophobicContact CH2-CD1 4.11Å; W180-Y184 AromaticContact CH2-CD2 3.42Å; W180-Y184 HydrophobicContact CH2-CD2 3.42Å; W180-Y184 VanDerWaalsContact CH2-CD2 3.42Å; W180-Y184 HydrophobicContact CH2-CE1 4.5Å; W180-Y184 AromaticContact CH2-CE2 3.92Å; W180-Y184 HydrophobicContact CH2-CE2 3.92Å; W180-Y184 AromaticContact CH2-CG 3.53Å; W180-Y184 HydrophobicContact CH2-CG 3.53Å; W180-Y184 AromaticContact CZ2-CD2 3.61Å; W180-Y184 HydrophobicContact CZ2-CD2 3.61Å; W180-Y184 HydrophobicContact CZ2-CE2 4.19Å; W180-Y184 HydrophobicContact CZ2-CG 4.08Å; W180-Y184 HydrophobicContact CZ3-CD1 4.27Å; W180-Y184 HydrophobicContact CZ3-CD2 4.18Å; W180-Y184 AromaticContact CZ3-CG 3.81Å; W180-Y184 HydrophobicContact CZ3-CG 3.81Å; W180-Y184 WeakPolarHBondContact O-CB 3.45Å; W180-Y184 PolarHBondContact O-N 3.26Å; W180-L291 HydrophobicContact CZ2-CD1 4.49Å; W180-C292 PolarHBondContact NE1-O 3.27Å; W180-C292 VanDerWaalsContact NE1-O 3.16Å; W180-P431 HydrophobicContact CZ3-CG 4.07Å
181I98.4Very high98Very high0 Ų010.6 Ų10.60%06%0.055CC..Hα-helixtrans-56.6-47.5174.5-76.9168000110.8Q20 L177 F178 Y184 V185 W213 F217 P431 F432Q20-I181 VanDerWaalsContact NE2-CG1 3.29Å; L177-I181 HydrophobicContact CD1-CD1 4.43Å; L177-I181 HydrophobicContact CG-CD1 4.07Å; L177-I181 VanDerWaalsContact O-CG1 3.28Å; L177-I181 WeakPolarHBondContact O-CG1 3.03Å; L177-I181 PolarHBondContact O-N 3.46Å; F178-I181 HydrophobicContact CD1-CD1 4.16Å; F178-I181 HydrophobicContact CE1-CD1 4.31Å; I181-Y184 PolarHBondContact O-N 3.04Å; I181-V185 PolarHBondContact O-N 3.15Å; I181-W213 HydrophobicContact CG2-CH2 3.85Å; I181-W213 HydrophobicContact CG2-CZ2 3.73Å; I181-F217 HydrophobicContact CB-CE2 4.08Å; I181-F217 HydrophobicContact CG2-CD2 3.78Å; I181-F217 HydrophobicContact CG2-CE2 3.65Å; I181-P431 HydrophobicContact CG1-CG 4.22Å; I181-P431 HydrophobicContact CG2-CG 4.38Å; I181-F432 HydrophobicContact CD1-CE1 4.44Å; I181-F432 HydrophobicContact CG2-CE1 4Å; I181-F432 HydrophobicContact CG2-CZ 4.33Å
182H98.6Very high97.8Very high0 Ų09.2 Ų9.20%06%0.057CC..Hα-helixtrans-67.8-39.4179.5-169.9-91.7000112.5F178 V179 W180 Y184 V185 S186 H205 W213 H214 F217 V380 S383 A384 F389F178-H182 WeakPolarHBondContact O-CB 3.42Å; F178-H182 PolarHBondContact O-N 2.9Å; F178-H182 VanDerWaalsContact O-N 3.1Å; V179-H182 PolarHBondContact O-N 3.21Å; W180-H182 VanDerWaalsContact C-N 3.33Å; W180-H182 PolarHBondContact O-N 2.99Å; H182-Y184 PolarHBondContact O-N 3.46Å; H182-V185 WeakPolarHBondContact O-CG2 3.48Å; H182-S186 PolarHBondContact O-N 3.41Å; H182-S186 PolarHBondContact O-OG 3.37Å; H182-H205 AromaticContact CE1-CE1 3.5Å; H182-H205 PolarHBondContact CE1-CE1 2.85Å; H182-H205 VanDerWaalsContact CE1-CE1 3.5Å; H182-H205 AromaticContact CE1-NE2 3.65Å; H182-H205 AromaticContact NE2-CE1 3.11Å; H182-H205 PolarHBondContact NE2-CE1 3.4Å; H182-H205 AromaticContact NE2-NE2 3.04Å; H182-H205 PolarHBondContact NE2-NE2 3.15Å; H182-W213 AromaticContact CD2-CZ3 3.93Å; H182-H214 AromaticContact CD2-NE2 3.79Å; H182-H214 AromaticContact NE2-NE2 3.53Å; H182-F217 HydrophobicContact CB-CE2 4.38Å; H182-F217 HydrophobicContact CB-CZ 4.18Å; H182-V380 PolarHBondContact CE1-O 3.28Å; H182-V380 PolarHBondContact ND1-O 3.27Å; H182-V380 VanDerWaalsContact ND1-O 3.11Å; H182-S383 PolarHBondContact CE1-OG 3.06Å; H182-A384 HydrophobicContact CB-CB 4.16Å; H182-F389 AromaticContact CD2-CZ 3.77Å; H182-F389 AromaticContact NE2-CE2 3.84Å; H182-F389 AromaticContact NE2-CZ 3.84Å
183Y98.5Very high97.6Very high2 Ų210.4 Ų10.41%0.0087%0.07CC..Hα-helixtrans-57.4-48.3169.4156.2-97000111.9V179 W180 V185 S186 R187 C279 Y285 C292 Q381V179-Y183 PolarHBondContact O-N 3.47Å; W180-Y183 WeakPolarHBondContact O-CB 3.47Å; W180-Y183 PolarHBondContact O-N 3.08Å; Y183-V185 VanDerWaalsContact C-N 3.33Å; Y183-V185 PolarHBondContact O-N 2.98Å; Y183-S186 CarbonylContact O-C 3.57Å; Y183-S186 PolarHBondContact O-N 3.44Å; Y183-R187 HydrophobicContact CE2-CB 4.02Å; Y183-R187 PolarHBondContact O-N 3.01Å; Y183-C279 HydrophobicContact CD1-CB 4.32Å; Y183-C279 HydrophobicContact CD2-CB 3.76Å; Y183-C279 HydrophobicContact CG-CB 3.6Å; Y183-Y285 HydrophobicContact CD2-CE2 4.37Å; Y183-Y285 AromaticContact CE2-CD2 3.61Å; Y183-Y285 HydrophobicContact CE2-CD2 3.61Å; Y183-Y285 AromaticContact CE2-CE2 3.78Å; Y183-Y285 HydrophobicContact CE2-CE2 3.78Å; Y183-C292 HydrophobicContact CD1-CB 3.66Å; Y183-C292 HydrophobicContact CD2-CB 4.22Å; Y183-C292 HydrophobicContact CE1-CB 3.37Å; Y183-C292 HydrophobicContact CE2-CB 3.97Å; Y183-C292 HydrophobicContact CG-CB 4.1Å; Y183-C292 PolarHBondContact OH-N 3.15Å; Y183-C292 VanDerWaalsContact OH-N 3.17Å; Y183-Q381 HydrophobicContact CD2-CB 4.05Å; Y183-Q381 HydrophobicContact CD2-CG 4.22Å
184Y98.3Very high97.5Very high3 Ų314.5 Ų14.51%0.01210%0.098CC..Hα-helixtrans-67.8-32.5-171.2-171.5-102.4000112.5R78 W81 W180 I181 H182 S186 R187 L291 I430 P431R78-Y184 WeakPolarHBondContact CD-O 3.47Å; R78-Y184 HydrophobicContact CG-CD1 4.18Å; R78-Y184 HydrophobicContact CG-CE1 3.48Å; R78-Y184 VanDerWaalsContact CG-CE1 3.48Å; R78-Y184 PolarHBondContact NH1-O 3.33Å; W81-Y184 HydrophobicContact CZ3-CE1 4.36Å; W180-Y184 HydrophobicContact CH2-CD1 4.11Å; W180-Y184 AromaticContact CH2-CD2 3.42Å; W180-Y184 HydrophobicContact CH2-CD2 3.42Å; W180-Y184 VanDerWaalsContact CH2-CD2 3.42Å; W180-Y184 HydrophobicContact CH2-CE1 4.5Å; W180-Y184 AromaticContact CH2-CE2 3.92Å; W180-Y184 HydrophobicContact CH2-CE2 3.92Å; W180-Y184 AromaticContact CH2-CG 3.53Å; W180-Y184 HydrophobicContact CH2-CG 3.53Å; W180-Y184 AromaticContact CZ2-CD2 3.61Å; W180-Y184 HydrophobicContact CZ2-CD2 3.61Å; W180-Y184 HydrophobicContact CZ2-CE2 4.19Å; W180-Y184 HydrophobicContact CZ2-CG 4.08Å; W180-Y184 HydrophobicContact CZ3-CD1 4.27Å; W180-Y184 HydrophobicContact CZ3-CD2 4.18Å; W180-Y184 AromaticContact CZ3-CG 3.81Å; W180-Y184 HydrophobicContact CZ3-CG 3.81Å; W180-Y184 WeakPolarHBondContact O-CB 3.45Å; W180-Y184 PolarHBondContact O-N 3.26Å; I181-Y184 PolarHBondContact O-N 3.04Å; H182-Y184 PolarHBondContact O-N 3.46Å; Y184-S186 VanDerWaalsContact C-N 3.33Å; Y184-R187 WeakPolarHBondContact O-CG 3.19Å; Y184-L291 HydrophobicContact CD2-CD1 4.41Å; Y184-L291 HydrophobicContact CE2-CD1 3.94Å; Y184-I430 HydrophobicContact CD1-CG2 3.94Å; Y184-I430 HydrophobicContact CE1-CG2 3.95Å; Y184-P431 HydrophobicContact CD1-CB 3.62Å; Y184-P431 HydrophobicContact CD1-CG 3.71Å; Y184-P431 HydrophobicContact CE1-CB 3.86Å; Y184-P431 HydrophobicContact CE1-CG 4.44Å; Y184-P431 HydrophobicContact CG-CG 4.43Å
185V97.8Very high97.2Very high0 Ų015.5 Ų15.50%011%0.108CC..Hα-helixtrans-72.6-26.6173.1-62.90000113.3R78 I181 H182 Y183 F203 A204 W213 I430R78-V185 PolarHBondContact NH1-O 3.23Å; I181-V185 PolarHBondContact O-N 3.15Å; H182-V185 WeakPolarHBondContact O-CG2 3.48Å; Y183-V185 VanDerWaalsContact C-N 3.33Å; Y183-V185 PolarHBondContact O-N 2.98Å; V185-F203 HydrophobicContact CB-CB 4.05Å; V185-F203 HydrophobicContact CG1-CB 4.38Å; V185-F203 PolarHBondContact O-N 2.96Å; V185-F203 VanDerWaalsContact O-N 3.15Å; V185-A204 HydrophobicContact CB-CB 3.94Å; V185-A204 HydrophobicContact CG2-CB 3.51Å; V185-W213 HydrophobicContact CB-CZ2 4.22Å; V185-W213 HydrophobicContact CG1-CH2 4.48Å; V185-W213 HydrophobicContact CG1-CZ2 3.53Å; V185-W213 HydrophobicContact CG2-CH2 3.89Å; V185-W213 HydrophobicContact CG2-CZ2 3.71Å; V185-I430 HydrophobicContact CG1-CB 4.05Å; V185-I430 HydrophobicContact CG1-CG2 4.09Å; V185-I430 WeakPolarHBondContact CG1-O 3.44Å
186S97.4Very high97.2Very high7 Ų719.3 Ų19.35%0.04913%0.129CC..Hα-helixtrans-105.63.2-173.2-370000113.8H182 Y183 Y184 D202 H205 Q381H182-S186 PolarHBondContact O-N 3.41Å; H182-S186 PolarHBondContact O-OG 3.37Å; Y183-S186 CarbonylContact O-C 3.57Å; Y183-S186 PolarHBondContact O-N 3.44Å; Y184-S186 VanDerWaalsContact C-N 3.33Å; S186-D202 WeakPolarHBondContact CB-OD2 3.42Å; S186-H205 PolarHBondContact OG-CE1 3.45Å; S186-Q381 PolarHBondContact O-NE2 2.03Å; S186-Q381 VanDerWaalsContact O-NE2 3.08Å
187R97.1Very high97.1Very high9 Ų919.6 Ų19.63%0.03413%0.13CC..PPolyproline II helixtrans-74.2149.7177.666.5161.8-80.3-78.87.4112D76 R78 Y183 Y184 F190D76-R187 IonicContact OD1-NH1 2.75Å; D76-R187 IonicContact OD2-NH1 3.11Å; D76-R187 PolarHBondContact OD2-NH1 3.27Å; R78-R187 VanDerWaalsContact CZ-O 3.25Å; R78-R187 VanDerWaalsContact NH1-CG 3.29Å; R78-R187 PolarHBondContact NH1-O 3.48Å; R78-R187 PolarHBondContact NH2-O 3.3Å; Y183-R187 HydrophobicContact CE2-CB 4.02Å; Y183-R187 PolarHBondContact O-N 3.01Å; Y184-R187 WeakPolarHBondContact O-CG 3.19Å; R187-F190 VanDerWaalsContact NH2-CD1 3.27Å; R187-F190 VanDerWaalsContact NH2-CE2 3.32Å
188D97.9Very high97.1Very high16 Ų1623 Ų239%0.08614%0.143CC..PPolyproline II helixtrans-67.2151.4173.6-57.5-33.8000110.8V197 W198 R199 N286D188-V197 HydrophobicContact CB-CB 3.8Å; D188-V197 HydrophobicContact CB-CG1 4.44Å; D188-V197 HydrophobicContact CB-CG2 3.85Å; D188-W198 WeakPolarHBondContact CA-O 3.49Å; D188-W198 WeakPolarHBondContact CB-O 3.41Å; D188-R199 WeakPolarHBondContact OD1-CA 3.25Å; D188-R199 IonicContact OD2-NE 2.76Å; D188-N286 PolarHBondContact OD2-ND2 3.43Å
189T98.1Very high96.9Very high0 Ų029.5 Ų29.50%017%0.168CC..EExtended strand (participates in β ladder)trans-77.6133.9172.2-66.80000110.2Y70 I75 D76 L191 V197 W198 I201Y70-T189 HydrophobicContact CE2-CG2 4.37Å; I75-T189 HydrophobicContact CD1-CG2 3.57Å; I75-T189 HydrophobicContact CG1-CG2 3.87Å; D76-T189 HydrophobicContact CB-CG2 3.87Å; D76-T189 WeakPolarHBondContact OD2-CA 3.49Å; D76-T189 VanDerWaalsContact OD2-CB 3.31Å; D76-T189 WeakPolarHBondContact OD2-CB 3.32Å; D76-T189 PolarHBondContact OD2-OG1 3.25Å; T189-L191 HydrophobicContact CG2-CD2 4.15Å; T189-V197 CarbonylContact O-C 3.53Å; T189-V197 WeakPolarHBondContact O-CA 3.4Å; T189-V197 VanDerWaalsContact O-CB 3.28Å; T189-V197 WeakPolarHBondContact O-CB 3.26Å; T189-W198 PolarHBondContact N-O 3.38Å; T189-W198 PolarHBondContact O-N 3.05Å; T189-I201 WeakPolarHBondContact OG1-CD1 3.39Å
190F97.4Very high96.8Very high21 Ų2132.4 Ų32.49%0.09218%0.183CC..EExtended strand (participates in β ladder)trans-79.2127174.4-57.2-26.1000110T156 R187 V197 E289 V290 L291T156-F190 HydrophobicContact CG2-CD2 4.17Å; T156-F190 HydrophobicContact CG2-CE2 4.36Å; R187-F190 VanDerWaalsContact NH2-CD1 3.27Å; R187-F190 VanDerWaalsContact NH2-CE2 3.32Å; F190-V197 HydrophobicContact CD1-CG1 3.84Å; F190-V197 HydrophobicContact CE1-CG1 4.44Å; F190-E289 HydrophobicContact CD2-CB 4.28Å; F190-E289 VanDerWaalsContact CE2-C 3.48Å; F190-V290 WeakPolarHBondContact CZ-O 3.36Å; F190-L291 HydrophobicContact CE2-CD2 4.1Å; F190-L291 HydrophobicContact CZ-CD2 4.37Å
191L96.3Very high96.7Very high57 Ų5732.9 Ų32.930%0.29819%0.186SC..  trans-102.14.2179.2-56.9-177.8000112.6I75 T189 N196 W198I75-L191 HydrophobicContact CD1-CD2 3.37Å; T189-L191 HydrophobicContact CG2-CD2 4.15Å; L191-N196 WeakPolarHBondContact CB-O 3.5Å; L191-N196 PolarHBondContact N-O 2.98Å; L191-W198 HydrophobicContact CD1-CB 4.19Å; L191-W198 HydrophobicContact CD2-CB 4.13Å; L191-W198 HydrophobicContact CG-CB 4.32Å
192G93.2Very high96.6Very high40 Ų4033.9 Ų33.941%0.41219%0.192SC..SBendtrans88.3125.7-175.100000112.5N196 E289G192-N196 WeakPolarHBondContact O-CB 3.49Å; G192-N196 PolarHBondContact O-ND2 2.93Å; G192-E289 VanDerWaalsContact CA-OE2 3.31Å; G192-E289 WeakPolarHBondContact CA-OE2 3.48Å
193G92.6Very high96.6Very high29 Ų2933.9 Ų33.930%0.29919%0.192SC..SBendtrans97.8147.7-178.500000113.1G195 N196 E289G193-G195 PolarHBondContact O-N 3.32Å; G193-G195 VanDerWaalsContact O-N 3.14Å; G193-N196 WeakPolarHBondContact O-CB 3.41Å; G193-N196 PolarHBondContact O-N 2.96Å; G193-E289 WeakPolarHBondContact CA-OE1 3.45Å; G193-E289 PolarHBondContact N-OE1 3.44Å; G193-E289 PolarHBondContact N-OE2 3.2Å; G193-E289 VanDerWaalsContact N-OE2 3.07Å
194P94.8Very high96.6Very high108 Ų10833.8 Ų33.870%0.70119%0.191SC*.THydrogen-bonded Turntrans-52.5117.5-177.2-32.137.7000113.8N196 N287P194-N196 PolarHBondContact O-N 2.95Å; P194-N287 WeakPolarHBondContact CA-O 3.39Å; P194-N287 VanDerWaalsContact CB-O 3.25Å; P194-N287 WeakPolarHBondContact CB-O 3.46Å
195G94.1Very high96.6Very high21 Ų2134.2 Ų34.222%0.21619%0.193CC..THydrogen-bonded Turntrans74.61.617500000114.3G193 V197 N286G193-G195 PolarHBondContact O-N 3.32Å; G193-G195 VanDerWaalsContact O-N 3.14Å; G195-V197 PolarHBondContact O-N 3.27Å; G195-N286 WeakPolarHBondContact CA-O 3.14Å; G195-N286 PolarHBondContact N-O 3.25Å
196N96.8Very high96.7Very high81 Ų8136.9 Ų36.943%0.43321%0.206SC..  trans-82.293.4175.6-175.528.7000109.6L191 G192 G193 P194L191-N196 WeakPolarHBondContact CB-O 3.5Å; L191-N196 PolarHBondContact N-O 2.98Å; G192-N196 WeakPolarHBondContact O-CB 3.49Å; G192-N196 PolarHBondContact O-ND2 2.93Å; G193-N196 WeakPolarHBondContact O-CB 3.41Å; G193-N196 PolarHBondContact O-N 2.96Å; P194-N196 PolarHBondContact O-N 2.95Å
197V97.6Very high96.7Very high15 Ų1536.6 Ų36.69%0.09120%0.204CC..EExtended strand (participates in β ladder)trans-134.1151.4-173.2-56.60000112.4D188 T189 F190 G195 R199 N286D188-V197 HydrophobicContact CB-CB 3.8Å; D188-V197 HydrophobicContact CB-CG1 4.44Å; D188-V197 HydrophobicContact CB-CG2 3.85Å; T189-V197 CarbonylContact O-C 3.53Å; T189-V197 WeakPolarHBondContact O-CA 3.4Å; T189-V197 VanDerWaalsContact O-CB 3.28Å; T189-V197 WeakPolarHBondContact O-CB 3.26Å; F190-V197 HydrophobicContact CD1-CG1 3.84Å; F190-V197 HydrophobicContact CE1-CG1 4.44Å; G195-V197 PolarHBondContact O-N 3.27Å; V197-R199 HydrophobicContact CG2-CG 3.94Å; V197-N286 HydrophobicContact CG1-CB 3.81Å; V197-N286 HydrophobicContact CG2-CB 4.48Å
198W97.6Very high96.8Very high72 Ų7236.1 Ų36.127%0.27320%0.202SC..EExtended strand (participates in β ladder)trans-93.5117.3166.5-176.4-91.8000109.5Q69 Y70 P71 H72 D188 T189 L191 D200 I201Q69-W198 WeakPolarHBondContact O-CZ2 3.41Å; Y70-W198 AromaticContact CD2-CD1 3.7Å; Y70-W198 HydrophobicContact CD2-CG 4.42Å; Y70-W198 AromaticContact CD2-NE1 3.86Å; Y70-W198 HydrophobicContact CE2-CG 4.47Å; P71-W198 HydrophobicContact CG-CE3 4.46Å; P71-W198 HydrophobicContact CG-CH2 3.85Å; P71-W198 HydrophobicContact CG-CZ2 4.11Å; P71-W198 HydrophobicContact CG-CZ3 4.04Å; H72-W198 AromaticContact NE2-CD2 3.73Å; H72-W198 AromaticContact NE2-CE3 3.44Å; H72-W198 AromaticContact NE2-CG 3.99Å; D188-W198 WeakPolarHBondContact CA-O 3.49Å; D188-W198 WeakPolarHBondContact CB-O 3.41Å; T189-W198 PolarHBondContact N-O 3.38Å; T189-W198 PolarHBondContact O-N 3.05Å; L191-W198 HydrophobicContact CD1-CB 4.19Å; L191-W198 HydrophobicContact CD2-CB 4.13Å; L191-W198 HydrophobicContact CG-CB 4.32Å; W198-D200 HydrophobicContact CZ2-CB 3.94Å; W198-D200 PolarHBondContact NE1-O 3Å; W198-I201 WeakPolarHBondContact O-CG2 3.47Å
199R96.1Very high96.8Very high136 Ų13635.4 Ų35.451%0.51320%0.198SC..  trans-94.9-19.9-174.8-61.7-171.5169.277.2-2.8114.6D188 V197 I201 E283D188-R199 WeakPolarHBondContact OD1-CA 3.25Å; D188-R199 IonicContact OD2-NE 2.76Å; V197-R199 HydrophobicContact CG2-CG 3.94Å; R199-I201 PolarHBondContact O-N 3.37Å; R199-E283 IonicContact NH2-OE1 3.63Å; R199-E283 IonicContact NH2-OE2 3.31Å; R199-E283 PolarHBondContact NH2-OE2 3.3Å
200D95.1Very high96.8Very high61 Ų6135.4 Ų35.433%0.32620%0.198SC..SBendtrans-85.359.9-177.2-154.338000109.9W198 R337W198-D200 HydrophobicContact CZ2-CB 3.94Å; W198-D200 PolarHBondContact NE1-O 3Å; D200-R337 IonicContact OD1-CZ 3.31Å; D200-R337 IonicContact OD1-NH1 3.95Å; D200-R337 PolarHBondContact OD1-NH1 2.85Å; D200-R337 IonicContact OD1-NH2 3.36Å; D200-R337 PolarHBondContact OD1-NH2 3.33Å; D200-R337 IonicContact OD2-NH2 2.71Å
201I96.6Very high96.9Very high13 Ų1334.6 Ų34.67%0.06719%0.194CC..  trans-150.4127.6179.8-172.4172.2000110.2Y70 T189 W198 R199 F203 I421Y70-I201 HydrophobicContact CD2-CB 4.37Å; Y70-I201 HydrophobicContact CD2-CD1 3.73Å; Y70-I201 HydrophobicContact CD2-CG1 4.39Å; Y70-I201 HydrophobicContact CE2-CD1 3.6Å; Y70-I201 HydrophobicContact CG-CD1 4.34Å; T189-I201 WeakPolarHBondContact OG1-CD1 3.39Å; W198-I201 WeakPolarHBondContact O-CG2 3.47Å; R199-I201 PolarHBondContact O-N 3.37Å; I201-F203 HydrophobicContact CD1-CD2 4.39Å; I201-F203 HydrophobicContact CD1-CE2 3.42Å; I201-F203 VanDerWaalsContact CD1-CE2 3.42Å; I201-F203 HydrophobicContact CD1-CZ 3.78Å; I201-F203 HydrophobicContact CG1-CD2 4.24Å; I201-F203 HydrophobicContact CG1-CE2 3.72Å; I201-F203 HydrophobicContact CG1-CZ 4.31Å; I201-I421 HydrophobicContact CD1-CG2 4.16Å; I201-I421 HydrophobicContact CG1-CG2 4.16Å
202D97.9Very high97Very high21 Ų2131.9 Ų31.911%0.11218%0.18CC..  trans-147.4146.1169-163.5-58.5000107.1S186 A204 H205 H423S186-D202 WeakPolarHBondContact CB-OD2 3.42Å; D202-A204 WeakPolarHBondContact OD1-CA 3.47Å; D202-A204 PolarHBondContact OD1-N 2.71Å; D202-H205 HydrophobicContact CB-CB 4.36Å; D202-H205 IonicContact OD1-CG 3.47Å; D202-H205 PolarHBondContact OD1-N 3.43Å; D202-H205 IonicContact OD1-ND1 3.62Å; D202-H205 PolarHBondContact OD1-ND1 3.03Å; D202-H205 IonicContact OD2-CE1 2.81Å; D202-H205 IonicContact OD2-CG 2.79Å; D202-H205 IonicContact OD2-ND1 3.82Å; D202-H205 PolarHBondContact OD2-ND1 3.24Å; D202-H423 PolarHBondContact O-NE2 3.25Å
203F98.5Very high97.3Very high0 Ų030 Ų300%016%0.161CC..SBendtrans-109.1-1-177.9-75-87.6000113.4R78 V185 I201 I421 Y427 I430R78-F203 HydrophobicContact CB-CD2 4.19Å; R78-F203 HydrophobicContact CB-CE1 4.14Å; R78-F203 HydrophobicContact CB-CE2 3.57Å; R78-F203 HydrophobicContact CB-CZ 3.53Å; R78-F203 HydrophobicContact CG-CE2 4.34Å; V185-F203 HydrophobicContact CB-CB 4.05Å; V185-F203 HydrophobicContact CG1-CB 4.38Å; V185-F203 PolarHBondContact O-N 2.96Å; V185-F203 VanDerWaalsContact O-N 3.15Å; I201-F203 HydrophobicContact CD1-CD2 4.39Å; I201-F203 HydrophobicContact CD1-CE2 3.42Å; I201-F203 VanDerWaalsContact CD1-CE2 3.42Å; I201-F203 HydrophobicContact CD1-CZ 3.78Å; I201-F203 HydrophobicContact CG1-CD2 4.24Å; I201-F203 HydrophobicContact CG1-CE2 3.72Å; I201-F203 HydrophobicContact CG1-CZ 4.31Å; F203-I421 HydrophobicContact CE1-CD1 4.49Å; F203-I421 HydrophobicContact CE1-CG1 4Å; F203-I421 HydrophobicContact CE1-CG2 4.38Å; F203-I421 HydrophobicContact CZ-CD1 4.44Å; F203-I421 HydrophobicContact CZ-CG1 4.36Å; F203-I421 HydrophobicContact CZ-CG2 4.32Å; F203-Y427 HydrophobicContact CE1-CE1 4.47Å; F203-I430 HydrophobicContact CB-CB 4.33Å; F203-I430 HydrophobicContact CB-CD1 3.94Å; F203-I430 HydrophobicContact CB-CG1 4.4Å; F203-I430 HydrophobicContact CD1-CD1 3.2Å; F203-I430 HydrophobicContact CD1-CG1 3.86Å; F203-I430 HydrophobicContact CE1-CD1 3.88Å; F203-I430 HydrophobicContact CE1-CG1 4.34Å; F203-I430 HydrophobicContact CG-CD1 3.83Å; F203-I430 HydrophobicContact CG-CG1 4.2Å
204A98.4Very high97.6Very high0 Ų028.9 Ų28.90%015%0.148CC..SBendtrans-137.7-6.4-175.300000113.6V185 D202 F210 W213 H214V185-A204 HydrophobicContact CB-CB 3.94Å; V185-A204 HydrophobicContact CG2-CB 3.51Å; D202-A204 WeakPolarHBondContact OD1-CA 3.47Å; D202-A204 PolarHBondContact OD1-N 2.71Å; A204-F210 VanDerWaalsContact O-CA 3.25Å; A204-F210 WeakPolarHBondContact O-CA 3.39Å; A204-W213 HydrophobicContact CB-CB 4.42Å; A204-W213 HydrophobicContact CB-CD2 3.39Å; A204-W213 HydrophobicContact CB-CE3 3.56Å; A204-W213 HydrophobicContact CB-CG 3.75Å; A204-W213 HydrophobicContact CB-CH2 4.34Å; A204-W213 HydrophobicContact CB-CZ2 4.19Å; A204-W213 HydrophobicContact CB-CZ3 4.05Å; A204-H214 PolarHBondContact O-CE1 2.91Å; A204-H214 VanDerWaalsContact O-CE1 3.27Å
205H98.7Very high97.8Very high12 Ų1223.7 Ų23.76%0.05611%0.114CC..SBendtrans-133.6174.1179.9-4994000111.6H182 S186 D202 S207 H214 E348 H423H182-H205 AromaticContact CE1-CE1 3.5Å; H182-H205 PolarHBondContact CE1-CE1 2.85Å; H182-H205 VanDerWaalsContact CE1-CE1 3.5Å; H182-H205 AromaticContact CE1-NE2 3.65Å; H182-H205 AromaticContact NE2-CE1 3.11Å; H182-H205 PolarHBondContact NE2-CE1 3.4Å; H182-H205 AromaticContact NE2-NE2 3.04Å; H182-H205 PolarHBondContact NE2-NE2 3.15Å; S186-H205 PolarHBondContact OG-CE1 3.45Å; D202-H205 HydrophobicContact CB-CB 4.36Å; D202-H205 IonicContact OD1-CG 3.47Å; D202-H205 PolarHBondContact OD1-N 3.43Å; D202-H205 IonicContact OD1-ND1 3.62Å; D202-H205 PolarHBondContact OD1-ND1 3.03Å; D202-H205 IonicContact OD2-CE1 2.81Å; D202-H205 IonicContact OD2-CG 2.79Å; D202-H205 IonicContact OD2-ND1 3.82Å; D202-H205 PolarHBondContact OD2-ND1 3.24Å; H205-S207 PolarHBondContact O-N 2.78Å; H205-H214 AromaticContact CD2-CE1 3.53Å; H205-H214 AromaticContact NE2-CE1 3.28Å; H205-H214 PolarHBondContact NE2-CE1 3.06Å; H205-H214 VanDerWaalsContact NE2-CE1 3.28Å; H205-H214 AromaticContact NE2-NE2 3.37Å; H205-H214 PolarHBondContact NE2-NE2 3.22Å; H205-E348 WeakPolarHBondContact CA-OE1 3.47Å; H205-E348 WeakPolarHBondContact CB-OE1 3.32Å; H205-H423 PolarHBondContact O-CE1 2.75Å; H205-H423 PolarHBondContact O-NE2 2.66Å
206E98.1Very high98Very high55 Ų5522.7 Ų22.726%0.25710%0.104SC..SBendtrans62.84.3173-47.2-161.8171.200115.3D336 R337 R344 E348 F350E206-D336 CarbonylContact O-C 3.36Å; E206-D336 WeakPolarHBondContact O-CA 3.31Å; E206-R337 HydrophobicContact CB-CB 4.25Å; E206-R337 PolarHBondContact O-N 3.08Å; E206-R337 IonicContact OE1-NH1 3.33Å; E206-R337 PolarHBondContact OE1-NH1 2.91Å; E206-R337 VanDerWaalsContact OE2-CD 3.29Å; E206-R337 WeakPolarHBondContact OE2-CD 3.24Å; E206-R337 IonicContact OE2-CZ 2.78Å; E206-R337 IonicContact OE2-NE 3.45Å; E206-R337 IonicContact OE2-NH1 3.83Å; E206-R337 PolarHBondContact OE2-NH1 3.47Å; E206-R344 VanDerWaalsContact C-NH1 3.25Å; E206-R344 PolarHBondContact O-NH1 2.73Å; E206-E348 PolarHBondContact N-OE1 3.44Å; E206-E348 PolarHBondContact N-OE2 2.78Å; E206-F350 HydrophobicContact CB-CE2 4.41Å; E206-F350 HydrophobicContact CG-CE2 3.9Å; E206-F350 HydrophobicContact CG-CZ 3.78Å
207S98.3Very high98.1Very high1 Ų118.9 Ų18.91%0.0078%0.083CC..SBendtrans-161.1-178-177.3-176.20000112.5H205 A209 F210 M335 R344 P420 H423H205-S207 PolarHBondContact O-N 2.78Å; S207-A209 VanDerWaalsContact C-N 3.27Å; S207-A209 PolarHBondContact O-N 3.03Å; S207-F210 WeakPolarHBondContact O-CB 3.45Å; S207-F210 PolarHBondContact O-N 3.05Å; S207-M335 WeakPolarHBondContact CB-O 3.03Å; S207-M335 PolarHBondContact OG-O 3.27Å; S207-R344 WeakPolarHBondContact O-CD 3.26Å; S207-P420 VanDerWaalsContact OG-CD 3.25Å; S207-P420 WeakPolarHBondContact OG-CD 3.46Å; S207-P420 WeakPolarHBondContact OG-CG 3.39Å; S207-H423 VanDerWaalsContact C-ND1 3.33Å; S207-H423 VanDerWaalsContact CB-CG 3.41Å; S207-H423 VanDerWaalsContact CB-ND1 3.3Å; S207-H423 WeakPolarHBondContact CB-ND1 3.1Å; S207-H423 PolarHBondContact O-ND1 2.88Å; S207-H423 WeakPolarHBondContact OG-CB 3.46Å
208A98.2Very high98.1Very high0 Ų018.1 Ų18.10%08%0.079CC..THydrogen-bonded Turntrans-50.6-35.1-165.200000115.3F210 Y330 E331 Y414 P415 H423A208-F210 PolarHBondContact O-N 2.81Å; A208-Y330 HydrophobicContact CB-CE1 4.1Å; A208-Y330 PolarHBondContact O-OH 3.29Å; A208-E331 WeakPolarHBondContact CA-OE1 3.22Å; A208-E331 HydrophobicContact CB-CG 3.98Å; A208-E331 PolarHBondContact N-OE1 3.17Å; A208-E331 VanDerWaalsContact N-OE1 3.16Å; A208-Y414 HydrophobicContact CB-CE1 4.45Å; A208-Y414 HydrophobicContact CB-CE2 4.16Å; A208-Y414 WeakPolarHBondContact O-CE2 3.4Å; A208-Y414 PolarHBondContact O-OH 3.13Å; A208-P415 HydrophobicContact CB-CG 3.34Å; A208-H423 HydrophobicContact CB-CB 4.31Å
209A98.5Very high98.2Very high0 Ų015 Ų150%07%0.068CC..THydrogen-bonded Turntrans-69.2-9.6178.200000115.1S207 L211 P212 W213 Y414 H423 N438S207-A209 VanDerWaalsContact C-N 3.27Å; S207-A209 PolarHBondContact O-N 3.03Å; A209-L211 PolarHBondContact O-N 2.84Å; A209-P212 WeakPolarHBondContact O-CD 3.48Å; A209-W213 HydrophobicContact CB-CB 4.49Å; A209-W213 WeakPolarHBondContact O-CB 3.44Å; A209-W213 PolarHBondContact O-N 2.98Å; A209-Y414 WeakPolarHBondContact CA-OH 3.43Å; A209-Y414 PolarHBondContact N-OH 2.71Å; A209-H423 HydrophobicContact CB-CB 4.22Å; A209-H423 VanDerWaalsContact CB-ND1 3.31Å; A209-H423 WeakPolarHBondContact CB-ND1 3.01Å; A209-H423 PolarHBondContact N-ND1 2.74Å; A209-N438 VanDerWaalsContact CB-OD1 3.28Å; A209-N438 WeakPolarHBondContact CB-OD1 3.41Å
210F98.9Very high98.2Very high0 Ų08.9 Ų8.90%05%0.045CC..Hα-helixtrans-47.6-52.6-175.6169.4-114.1000113.9A204 S207 A208 H214 R344 E348 H366 I396A204-F210 VanDerWaalsContact O-CA 3.25Å; A204-F210 WeakPolarHBondContact O-CA 3.39Å; S207-F210 WeakPolarHBondContact O-CB 3.45Å; S207-F210 PolarHBondContact O-N 3.05Å; A208-F210 PolarHBondContact O-N 2.81Å; F210-H214 AromaticContact CD2-CE1 3.66Å; F210-H214 AromaticContact CD2-ND1 3.5Å; F210-H214 WeakPolarHBondContact CD2-ND1 3.04Å; F210-H214 AromaticContact CE2-CE1 3.76Å; F210-H214 AromaticContact CE2-ND1 3.68Å; F210-H214 WeakPolarHBondContact O-CB 3.15Å; F210-H214 PolarHBondContact O-N 3.07Å; F210-H214 PolarHBondContact O-ND1 2.79Å; F210-R344 HydrophobicContact CB-CG 4.26Å; F210-R344 HydrophobicContact CD1-CG 4.42Å; F210-E348 HydrophobicContact CD1-CB 3.76Å; F210-E348 HydrophobicContact CD1-CG 3.98Å; F210-E348 HydrophobicContact CD2-CG 4.19Å; F210-E348 HydrophobicContact CE1-CB 3.7Å; F210-E348 HydrophobicContact CE1-CG 3.95Å; F210-E348 HydrophobicContact CE2-CG 4.15Å; F210-E348 HydrophobicContact CG-CB 4.37Å; F210-E348 HydrophobicContact CG-CG 4.13Å; F210-E348 HydrophobicContact CZ-CB 4.25Å; F210-E348 HydrophobicContact CZ-CG 4.04Å; F210-H366 AromaticContact CE2-CE1 3.74Å; F210-H366 AromaticContact CE2-NE2 3.74Å; F210-H366 HydrophobicContact CZ-CB 4.31Å; F210-H366 AromaticContact CZ-CD2 3.7Å; F210-H366 AromaticContact CZ-CE1 3.86Å; F210-H366 AromaticContact CZ-CG 3.73Å; F210-H366 AromaticContact CZ-ND1 3.83Å; F210-H366 AromaticContact CZ-NE2 3.76Å; F210-I396 HydrophobicContact CE1-CG2 4.1Å; F210-I396 HydrophobicContact CZ-CG2 4.12Å
211L98.8Very high98.4Very high4 Ų46 Ų62%0.0213%0.029CC..Hα-helixtrans-76.6-48.9-176.4-58.6169.4000112.7A209 W213 R215 Y330 F343 L347 I396 F400A209-L211 PolarHBondContact O-N 2.84Å; L211-W213 VanDerWaalsContact C-N 3.35Å; L211-W213 PolarHBondContact O-N 3.17Å; L211-R215 WeakPolarHBondContact O-CB 3.44Å; L211-R215 PolarHBondContact O-N 2.99Å; L211-Y330 HydrophobicContact CD1-CE2 3.99Å; L211-F343 HydrophobicContact CD1-CD1 4.24Å; L211-F343 HydrophobicContact CD1-CE1 3.53Å; L211-F343 HydrophobicContact CD1-CZ 4.22Å; L211-L347 HydrophobicContact CD1-CD2 4.05Å; L211-L347 HydrophobicContact CD2-CD2 3.8Å; L211-L347 HydrophobicContact CD2-CG 4.47Å; L211-I396 HydrophobicContact CD2-CG2 3.66Å; L211-F400 HydrophobicContact CB-CB 4.39Å; L211-F400 HydrophobicContact CB-CD1 3.55Å; L211-F400 HydrophobicContact CB-CD2 4.34Å; L211-F400 HydrophobicContact CB-CE1 3.84Å; L211-F400 HydrophobicContact CB-CG 3.85Å; L211-F400 HydrophobicContact CB-CZ 4.36Å; L211-F400 HydrophobicContact CD1-CB 4.07Å; L211-F400 HydrophobicContact CD1-CD1 4.41Å; L211-F400 HydrophobicContact CD1-CD2 3.78Å; L211-F400 HydrophobicContact CD1-CE2 4.34Å; L211-F400 HydrophobicContact CD1-CG 3.84Å; L211-F400 HydrophobicContact CD2-CB 4.26Å; L211-F400 HydrophobicContact CG-CB 4.48Å; L211-F400 HydrophobicContact CG-CD1 4.46Å; L211-F400 HydrophobicContact CG-CG 4.3Å
212P98.5Very high98.5Very high0 Ų05.4 Ų5.40%03%0.026CC..Hα-helixtrans-62.1-37.8177-25.335.6000113.9A209 R215 V216 Y330 Y414 M429A209-P212 WeakPolarHBondContact O-CD 3.48Å; P212-R215 WeakPolarHBondContact O-CB 3.44Å; P212-R215 PolarHBondContact O-N 3.16Å; P212-V216 PolarHBondContact O-N 3.42Å; P212-Y330 WeakPolarHBondContact CD-OH 3.41Å; P212-Y414 HydrophobicContact CG-CE2 3.84Å; P212-M429 HydrophobicContact CB-CE 3.77Å; P212-M429 WeakPolarHBondContact O-CE 3.17Å
213W98.9Very high98.4Very high0 Ų05.5 Ų5.50%03%0.027CC..Hα-helixtrans-64.7-51.1179.4-171.2100.8000110.8I181 H182 V185 A204 A209 L211 R215 V216 F217 I430 F432I181-W213 HydrophobicContact CG2-CH2 3.85Å; I181-W213 HydrophobicContact CG2-CZ2 3.73Å; H182-W213 AromaticContact CD2-CZ3 3.93Å; V185-W213 HydrophobicContact CB-CZ2 4.22Å; V185-W213 HydrophobicContact CG1-CH2 4.48Å; V185-W213 HydrophobicContact CG1-CZ2 3.53Å; V185-W213 HydrophobicContact CG2-CH2 3.89Å; V185-W213 HydrophobicContact CG2-CZ2 3.71Å; A204-W213 HydrophobicContact CB-CB 4.42Å; A204-W213 HydrophobicContact CB-CD2 3.39Å; A204-W213 HydrophobicContact CB-CE3 3.56Å; A204-W213 HydrophobicContact CB-CG 3.75Å; A204-W213 HydrophobicContact CB-CH2 4.34Å; A204-W213 HydrophobicContact CB-CZ2 4.19Å; A204-W213 HydrophobicContact CB-CZ3 4.05Å; A209-W213 HydrophobicContact CB-CB 4.49Å; A209-W213 WeakPolarHBondContact O-CB 3.44Å; A209-W213 PolarHBondContact O-N 2.98Å; L211-W213 VanDerWaalsContact C-N 3.35Å; L211-W213 PolarHBondContact O-N 3.17Å; W213-R215 VanDerWaalsContact C-N 3.25Å; W213-R215 PolarHBondContact O-N 3.35Å; W213-V216 PolarHBondContact O-N 3.03Å; W213-F217 HydrophobicContact CE3-CB 3.99Å; W213-F217 HydrophobicContact CE3-CG 4.39Å; W213-F217 HydrophobicContact CH2-CB 4.21Å; W213-F217 AromaticContact CH2-CD2 3.44Å; W213-F217 HydrophobicContact CH2-CD2 3.44Å; W213-F217 VanDerWaalsContact CH2-CD2 3.44Å; W213-F217 AromaticContact CH2-CE2 3.9Å; W213-F217 HydrophobicContact CH2-CE2 3.9Å; W213-F217 AromaticContact CH2-CG 3.89Å; W213-F217 HydrophobicContact CH2-CG 3.89Å; W213-F217 HydrophobicContact CZ2-CD2 4.24Å; W213-F217 HydrophobicContact CZ3-CB 3.73Å; W213-F217 HydrophobicContact CZ3-CD1 4.23Å; W213-F217 AromaticContact CZ3-CD2 3.71Å; W213-F217 HydrophobicContact CZ3-CD2 3.71Å; W213-F217 HydrophobicContact CZ3-CE2 4.34Å; W213-F217 AromaticContact CZ3-CG 3.63Å; W213-F217 HydrophobicContact CZ3-CG 3.63Å; W213-F217 VanDerWaalsContact O-CB 3.31Å; W213-F217 WeakPolarHBondContact O-CB 3.28Å; W213-F217 PolarHBondContact O-N 2.92Å; W213-I430 PolarHBondContact NE1-O 3.15Å; W213-F432 HydrophobicContact CD2-CE2 4.28Å; W213-F432 AromaticContact CE2-CE2 3.76Å; W213-F432 AromaticContact CE2-CZ 3.96Å; W213-F432 HydrophobicContact CG-CE2 4.43Å; W213-F432 HydrophobicContact CH2-CZ 4.45Å; W213-F432 HydrophobicContact CZ2-CE2 4.16Å; W213-F432 AromaticContact CZ2-CZ 3.92Å; W213-F432 HydrophobicContact CZ2-CZ 3.92Å; W213-F432 AromaticContact NE1-CE2 3.62Å
214H98.9Very high98.4Very high6 Ų65.5 Ų5.53%0.0283%0.027CC..Hα-helixtrans-65.7-29.1178.6-74.389.8000112.6H182 A204 H205 F210 F217 L218 H393H182-H214 AromaticContact CD2-NE2 3.79Å; H182-H214 AromaticContact NE2-NE2 3.53Å; A204-H214 PolarHBondContact O-CE1 2.91Å; A204-H214 VanDerWaalsContact O-CE1 3.27Å; H205-H214 AromaticContact CD2-CE1 3.53Å; H205-H214 AromaticContact NE2-CE1 3.28Å; H205-H214 PolarHBondContact NE2-CE1 3.06Å; H205-H214 VanDerWaalsContact NE2-CE1 3.28Å; H205-H214 AromaticContact NE2-NE2 3.37Å; H205-H214 PolarHBondContact NE2-NE2 3.22Å; F210-H214 AromaticContact CD2-CE1 3.66Å; F210-H214 AromaticContact CD2-ND1 3.5Å; F210-H214 WeakPolarHBondContact CD2-ND1 3.04Å; F210-H214 AromaticContact CE2-CE1 3.76Å; F210-H214 AromaticContact CE2-ND1 3.68Å; F210-H214 WeakPolarHBondContact O-CB 3.15Å; F210-H214 PolarHBondContact O-N 3.07Å; F210-H214 PolarHBondContact O-ND1 2.79Å; H214-F217 WeakPolarHBondContact O-CB 3.41Å; H214-L218 VanDerWaalsContact O-CG 3.29Å; H214-L218 WeakPolarHBondContact O-CG 3.02Å; H214-L218 PolarHBondContact O-N 3.49Å; H214-H393 AromaticContact CD2-CE1 3.23Å; H214-H393 PolarHBondContact CD2-CE1 3.33Å; H214-H393 AromaticContact CD2-ND1 3.16Å; H214-H393 PolarHBondContact CD2-ND1 2.82Å; H214-H393 AromaticContact CG-CE1 3.9Å; H214-H393 AromaticContact CG-ND1 3.57Å; H214-H393 AromaticContact NE2-CE1 3.41Å; H214-H393 PolarHBondContact NE2-CE1 3.26Å; H214-H393 AromaticContact NE2-ND1 3.84Å
215R98.8Very high98.4Very high0 Ų05.5 Ų5.50%03%0.027CC..Hα-helixtrans-62.2-51.5171.3171170.5-65-173.5-7.4112.1L211 P212 W213 F217 L218 L219 D397 F400 L443 N445 L448L211-R215 WeakPolarHBondContact O-CB 3.44Å; L211-R215 PolarHBondContact O-N 2.99Å; P212-R215 WeakPolarHBondContact O-CB 3.44Å; P212-R215 PolarHBondContact O-N 3.16Å; W213-R215 VanDerWaalsContact C-N 3.25Å; W213-R215 PolarHBondContact O-N 3.35Å; R215-F217 VanDerWaalsContact C-N 3.32Å; R215-L218 PolarHBondContact O-N 3.12Å; R215-L219 HydrophobicContact CG-CD1 4.21Å; R215-L219 WeakPolarHBondContact O-CG 3.44Å; R215-L219 PolarHBondContact O-N 3.04Å; R215-D397 IonicContact CZ-OD1 2.79Å; R215-D397 IonicContact NE-OD1 3.1Å; R215-D397 PolarHBondContact NE-OD1 2.91Å; R215-D397 IonicContact NH2-OD1 3.77Å; R215-D397 PolarHBondContact NH2-OD1 3.17Å; R215-F400 VanDerWaalsContact CZ-CE1 3.4Å; R215-L443 PolarHBondContact NH1-O 3Å; R215-N445 PolarHBondContact NE-OD1 3.35Å; R215-N445 PolarHBondContact NH1-OD1 3.17Å; R215-N445 VanDerWaalsContact NH1-OD1 3.11Å; R215-N445 PolarHBondContact NH2-OD1 3.5Å; R215-L448 HydrophobicContact CG-CD1 4.1Å
216V98.6Very high98.3Very high0 Ų05.7 Ų5.70%03%0.027CC..Hα-helixtrans-64.4-39.8176.8172.30000110.9P212 W213 L218 L219 H220 M429 F432 Y436 Y441P212-V216 PolarHBondContact O-N 3.42Å; W213-V216 PolarHBondContact O-N 3.03Å; V216-L218 PolarHBondContact O-N 3.08Å; V216-L219 PolarHBondContact O-N 3.47Å; V216-H220 WeakPolarHBondContact O-CB 3.3Å; V216-H220 PolarHBondContact O-N 3.16Å; V216-M429 HydrophobicContact CB-CE 4.39Å; V216-M429 HydrophobicContact CB-SD 3.71Å; V216-M429 HydrophobicContact CG1-SD 4.06Å; V216-M429 HydrophobicContact CG2-CE 3.72Å; V216-M429 HydrophobicContact CG2-SD 3.59Å; V216-M429 VanDerWaalsContact CG2-SD 3.59Å; V216-F432 HydrophobicContact CB-CE2 4.3Å; V216-F432 HydrophobicContact CG1-CD2 3.98Å; V216-F432 HydrophobicContact CG1-CE2 3.85Å; V216-F432 HydrophobicContact CG1-CG 4.48Å; V216-F432 HydrophobicContact CG1-CZ 4.24Å; V216-Y436 HydrophobicContact CG1-CD2 3.49Å; V216-Y436 VanDerWaalsContact CG1-CD2 3.49Å; V216-Y436 HydrophobicContact CG1-CE2 3.88Å; V216-Y436 HydrophobicContact CG1-CG 3.97Å; V216-Y441 HydrophobicContact CG2-CD1 3.26Å; V216-Y441 HydrophobicContact CG2-CD2 3.68Å; V216-Y441 HydrophobicContact CG2-CE1 3.52Å; V216-Y441 HydrophobicContact CG2-CE2 3.96Å; V216-Y441 HydrophobicContact CG2-CG 3.34Å
217F98.8Very high98.2Very high0 Ų05.6 Ų5.60%03%0.026CC..Hα-helixtrans-54.7-50.2175-177.3-106.5000112F178 I181 H182 W213 H214 R215 H220 W221 F389 F432F178-F217 HydrophobicContact CB-CE2 3.84Å; F178-F217 HydrophobicContact CB-CZ 3.69Å; F178-F217 HydrophobicContact CD1-CD2 4.04Å; F178-F217 AromaticContact CD1-CE2 3.69Å; F178-F217 HydrophobicContact CD1-CE2 3.69Å; F178-F217 HydrophobicContact CD1-CZ 4.15Å; F178-F217 HydrophobicContact CG-CE2 4.27Å; F178-F217 HydrophobicContact CG-CZ 4.41Å; F178-F217 WeakPolarHBondContact O-CE2 3.41Å; F178-F217 VanDerWaalsContact O-CZ 3.27Å; F178-F217 WeakPolarHBondContact O-CZ 3.44Å; I181-F217 HydrophobicContact CB-CE2 4.08Å; I181-F217 HydrophobicContact CG2-CD2 3.78Å; I181-F217 HydrophobicContact CG2-CE2 3.65Å; H182-F217 HydrophobicContact CB-CE2 4.38Å; H182-F217 HydrophobicContact CB-CZ 4.18Å; W213-F217 HydrophobicContact CE3-CB 3.99Å; W213-F217 HydrophobicContact CE3-CG 4.39Å; W213-F217 HydrophobicContact CH2-CB 4.21Å; W213-F217 AromaticContact CH2-CD2 3.44Å; W213-F217 HydrophobicContact CH2-CD2 3.44Å; W213-F217 VanDerWaalsContact CH2-CD2 3.44Å; W213-F217 AromaticContact CH2-CE2 3.9Å; W213-F217 HydrophobicContact CH2-CE2 3.9Å; W213-F217 AromaticContact CH2-CG 3.89Å; W213-F217 HydrophobicContact CH2-CG 3.89Å; W213-F217 HydrophobicContact CZ2-CD2 4.24Å; W213-F217 HydrophobicContact CZ3-CB 3.73Å; W213-F217 HydrophobicContact CZ3-CD1 4.23Å; W213-F217 AromaticContact CZ3-CD2 3.71Å; W213-F217 HydrophobicContact CZ3-CD2 3.71Å; W213-F217 HydrophobicContact CZ3-CE2 4.34Å; W213-F217 AromaticContact CZ3-CG 3.63Å; W213-F217 HydrophobicContact CZ3-CG 3.63Å; W213-F217 VanDerWaalsContact O-CB 3.31Å; W213-F217 WeakPolarHBondContact O-CB 3.28Å; W213-F217 PolarHBondContact O-N 2.92Å; H214-F217 WeakPolarHBondContact O-CB 3.41Å; R215-F217 VanDerWaalsContact C-N 3.32Å; F217-H220 PolarHBondContact O-N 2.95Å; F217-W221 HydrophobicContact CD1-CE3 4.18Å; F217-W221 AromaticContact CE1-CE3 3.38Å; F217-W221 HydrophobicContact CE1-CE3 3.38Å; F217-W221 AromaticContact CE1-CZ3 3.43Å; F217-W221 HydrophobicContact CE1-CZ3 3.43Å; F217-W221 VanDerWaalsContact CE1-CZ3 3.43Å; F217-W221 HydrophobicContact CE2-CE3 4.48Å; F217-W221 AromaticContact CZ-CE3 3.58Å; F217-W221 HydrophobicContact CZ-CE3 3.58Å; F217-W221 AromaticContact CZ-CZ3 3.5Å; F217-W221 HydrophobicContact CZ-CZ3 3.5Å; F217-W221 WeakPolarHBondContact O-CB 3.49Å; F217-W221 PolarHBondContact O-N 3.41Å; F217-F389 HydrophobicContact CD1-CE1 4.05Å; F217-F389 HydrophobicContact CE1-CD1 4.27Å; F217-F389 AromaticContact CE1-CE1 3.44Å; F217-F389 HydrophobicContact CE1-CE1 3.44Å; F217-F389 VanDerWaalsContact CE1-CE1 3.44Å; F217-F389 HydrophobicContact CE1-CZ 4.04Å; F217-F389 HydrophobicContact CZ-CE1 4.41Å; F217-F432 HydrophobicContact CB-CZ 3.9Å; F217-F432 HydrophobicContact CD2-CE1 4.25Å; F217-F432 HydrophobicContact CD2-CZ 4.02Å; F217-F432 HydrophobicContact CG-CZ 4.49Å
218L98.8Very high98.2Very high0 Ų07.2 Ų7.20%03%0.034CC..Hα-helixtrans-64.7-40.1176.9-70.4170.3000112.7H214 R215 V216 W221 E222 I236 L390 H393 A394 D397H214-L218 VanDerWaalsContact O-CG 3.29Å; H214-L218 WeakPolarHBondContact O-CG 3.02Å; H214-L218 PolarHBondContact O-N 3.49Å; R215-L218 PolarHBondContact O-N 3.12Å; V216-L218 PolarHBondContact O-N 3.08Å; L218-W221 PolarHBondContact O-N 2.9Å; L218-E222 VanDerWaalsContact O-CB 3.25Å; L218-E222 WeakPolarHBondContact O-CB 3.2Å; L218-E222 PolarHBondContact O-N 3.33Å; L218-I236 HydrophobicContact CD2-CD1 4.22Å; L218-L390 HydrophobicContact CD2-CD2 3.77Å; L218-H393 HydrophobicContact CD1-CB 4.11Å; L218-H393 HydrophobicContact CD2-CB 4.28Å; L218-H393 HydrophobicContact CG-CB 4.47Å; L218-A394 HydrophobicContact CD1-CB 4.43Å; L218-D397 HydrophobicContact CD1-CB 4.24Å
219L98.3Very high98.2Very high6 Ų68.8 Ų8.83%0.0314%0.044CC..Hα-helixtrans-64.7-42.1178.1-76168.5000111.9F106 R215 V216 N223 L448 Y450F106-L219 HydrophobicContact CD1-CB 4.03Å; F106-L219 HydrophobicContact CD1-CD2 4.4Å; F106-L219 HydrophobicContact CD2-CB 4.33Å; F106-L219 HydrophobicContact CD2-CD1 3.84Å; F106-L219 HydrophobicContact CE1-CB 3.71Å; F106-L219 HydrophobicContact CE2-CB 4.02Å; F106-L219 HydrophobicContact CE2-CD1 4.12Å; F106-L219 HydrophobicContact CG-CB 4.33Å; F106-L219 HydrophobicContact CG-CD1 4.09Å; F106-L219 HydrophobicContact CG-CD2 4.45Å; F106-L219 HydrophobicContact CZ-CB 3.71Å; R215-L219 HydrophobicContact CG-CD1 4.21Å; R215-L219 WeakPolarHBondContact O-CG 3.44Å; R215-L219 PolarHBondContact O-N 3.04Å; V216-L219 PolarHBondContact O-N 3.47Å; L219-N223 WeakPolarHBondContact O-CB 3.49Å; L219-N223 PolarHBondContact O-N 2.94Å; L219-L448 HydrophobicContact CD1-CB 4.29Å; L219-L448 HydrophobicContact CD1-CD1 3.91Å; L219-Y450 HydrophobicContact CD1-CE1 4.08Å; L219-Y450 HydrophobicContact CD2-CD1 3.77Å; L219-Y450 HydrophobicContact CD2-CE1 3.71Å; L219-Y450 HydrophobicContact CG-CE1 4.19Å
220H97.5Very high98.1Very high7 Ų711.1 Ų11.13%0.0327%0.067CC..Hα-helixtrans-66.9-43.2176.9-168.848.2000110.9Y150 F178 V216 F217 E222 N223 E224Y150-H220 AromaticContact CE2-CE1 3.57Å; Y150-H220 AromaticContact CE2-NE2 3.82Å; Y150-H220 AromaticContact CZ-CE1 3.76Å; Y150-H220 AromaticContact CZ-NE2 3.97Å; F178-H220 HydrophobicContact CE1-CB 3.96Å; F178-H220 AromaticContact CE1-CD2 3.43Å; F178-H220 VanDerWaalsContact CE1-CD2 3.43Å; F178-H220 WeakPolarHBondContact CE1-CD2 3.18Å; F178-H220 AromaticContact CE1-CG 3.9Å; F178-H220 HydrophobicContact CZ-CB 4.42Å; F178-H220 AromaticContact CZ-CD2 3.63Å; V216-H220 WeakPolarHBondContact O-CB 3.3Å; V216-H220 PolarHBondContact O-N 3.16Å; F217-H220 PolarHBondContact O-N 2.95Å; H220-E222 PolarHBondContact O-N 2.65Å; H220-N223 PolarHBondContact O-N 2.79Å; H220-E224 IonicContact CE1-OE1 2.78Å; H220-E224 WeakPolarHBondContact O-CG 3.39Å; H220-E224 PolarHBondContact O-N 2.91Å
221W98.4Very high98Very high0 Ų012.4 Ų12.40%07%0.074CC..Hα-helixtrans-61.2-45.4175.9-155.9-20000112.3Y175 F178 F217 L218 N223 E224 I225 I236 A384 F389 L390Y175-W221 AromaticContact CD1-CZ2 3.99Å; Y175-W221 HydrophobicContact CD1-CZ2 3.99Å; Y175-W221 AromaticContact CD2-CZ2 3.61Å; Y175-W221 HydrophobicContact CD2-CZ2 3.61Å; Y175-W221 HydrophobicContact CE1-CH2 4.04Å; Y175-W221 AromaticContact CE1-CZ2 3.86Å; Y175-W221 HydrophobicContact CE1-CZ2 3.86Å; Y175-W221 HydrophobicContact CE2-CH2 4.14Å; Y175-W221 AromaticContact CE2-CZ2 3.48Å; Y175-W221 HydrophobicContact CE2-CZ2 3.48Å; Y175-W221 VanDerWaalsContact CE2-CZ2 3.48Å; Y175-W221 AromaticContact CG-CZ2 3.84Å; Y175-W221 HydrophobicContact CG-CZ2 3.84Å; Y175-W221 AromaticContact CZ-CH2 3.8Å; Y175-W221 AromaticContact CZ-CZ2 3.58Å; F178-W221 HydrophobicContact CB-CD2 3.42Å; F178-W221 VanDerWaalsContact CB-CD2 3.42Å; F178-W221 HydrophobicContact CB-CE3 3.36Å; F178-W221 HydrophobicContact CB-CG 4.14Å; F178-W221 HydrophobicContact CB-CH2 3.63Å; F178-W221 HydrophobicContact CB-CZ2 3.66Å; F178-W221 HydrophobicContact CB-CZ3 3.49Å; F178-W221 VanDerWaalsContact CB-CZ3 3.49Å; F178-W221 HydrophobicContact CD1-CB 3.68Å; F178-W221 AromaticContact CD1-CD2 3.88Å; F178-W221 HydrophobicContact CD1-CD2 3.88Å; F178-W221 HydrophobicContact CD1-CE3 4.02Å; F178-W221 AromaticContact CD1-CG 3.78Å; F178-W221 HydrophobicContact CD1-CG 3.78Å; F178-W221 HydrophobicContact CD2-CB 4.1Å; F178-W221 AromaticContact CD2-CD1 3.38Å; F178-W221 AromaticContact CD2-CD2 3.66Å; F178-W221 HydrophobicContact CD2-CD2 3.66Å; F178-W221 AromaticContact CD2-CE2 3.69Å; F178-W221 HydrophobicContact CD2-CE3 4.44Å; F178-W221 AromaticContact CD2-CG 3.49Å; F178-W221 HydrophobicContact CD2-CG 3.49Å; F178-W221 VanDerWaalsContact CD2-CG 3.49Å; F178-W221 HydrophobicContact CD2-CZ2 4.45Å; F178-W221 AromaticContact CD2-NE1 3.51Å; F178-W221 HydrophobicContact CE1-CB 3.64Å; F178-W221 HydrophobicContact CE1-CG 4.09Å; F178-W221 HydrophobicContact CE2-CB 4.09Å; F178-W221 AromaticContact CE2-CD1 3.64Å; F178-W221 HydrophobicContact CE2-CD2 4.48Å; F178-W221 AromaticContact CE2-CG 3.85Å; F178-W221 HydrophobicContact CE2-CG 3.85Å; F178-W221 HydrophobicContact CG-CB 3.94Å; F178-W221 AromaticContact CG-CD1 3.89Å; F178-W221 AromaticContact CG-CD2 3.35Å; F178-W221 HydrophobicContact CG-CD2 3.35Å; F178-W221 AromaticContact CG-CE2 3.72Å; F178-W221 AromaticContact CG-CE3 3.68Å; F178-W221 HydrophobicContact CG-CE3 3.68Å; F178-W221 AromaticContact CG-CG 3.49Å; F178-W221 HydrophobicContact CG-CG 3.49Å; F178-W221 VanDerWaalsContact CG-CG 3.49Å; F178-W221 HydrophobicContact CG-CZ2 4.32Å; F178-W221 HydrophobicContact CG-CZ3 4.31Å; F178-W221 HydrophobicContact CZ-CB 3.89Å; F178-W221 HydrophobicContact CZ-CG 4.16Å; F217-W221 HydrophobicContact CD1-CE3 4.18Å; F217-W221 AromaticContact CE1-CE3 3.38Å; F217-W221 HydrophobicContact CE1-CE3 3.38Å; F217-W221 AromaticContact CE1-CZ3 3.43Å; F217-W221 HydrophobicContact CE1-CZ3 3.43Å; F217-W221 VanDerWaalsContact CE1-CZ3 3.43Å; F217-W221 HydrophobicContact CE2-CE3 4.48Å; F217-W221 AromaticContact CZ-CE3 3.58Å; F217-W221 HydrophobicContact CZ-CE3 3.58Å; F217-W221 AromaticContact CZ-CZ3 3.5Å; F217-W221 HydrophobicContact CZ-CZ3 3.5Å; F217-W221 WeakPolarHBondContact O-CB 3.49Å; F217-W221 PolarHBondContact O-N 3.41Å; L218-W221 PolarHBondContact O-N 2.9Å; W221-N223 VanDerWaalsContact C-N 3.31Å; W221-N223 PolarHBondContact O-N 3.43Å; W221-E224 PolarHBondContact O-N 3.11Å; W221-I225 WeakPolarHBondContact O-CG1 3.47Å; W221-I225 PolarHBondContact O-N 2.98Å; W221-I225 VanDerWaalsContact O-N 3.08Å; W221-I236 HydrophobicContact CB-CD1 4.31Å; W221-A384 HydrophobicContact CH2-CB 4.36Å; W221-A384 HydrophobicContact CZ3-CB 4.38Å; W221-F389 HydrophobicContact CZ3-CD1 4.31Å; W221-L390 HydrophobicContact CD2-CD2 3.66Å; W221-L390 HydrophobicContact CD2-CG 4.49Å; W221-L390 HydrophobicContact CE3-CD2 3.39Å; W221-L390 HydrophobicContact CE3-CG 4.31Å; W221-L390 HydrophobicContact CG-CD2 4.25Å; W221-L390 HydrophobicContact CH2-CD2 4.32Å; W221-L390 HydrophobicContact CH2-CG 4.4Å; W221-L390 HydrophobicContact CZ2-CD1 4.37Å; W221-L390 HydrophobicContact CZ3-CD2 3.75Å; W221-L390 HydrophobicContact CZ3-CG 4.24Å
222E98.6Very high97.8Very high1 Ų116.8 Ų16.81%0.0059%0.093CC..Hα-helixtrans-60.3-41.9176.4-167.9172.8-70.500111.5R121 L218 H220 I225 R226 F234 I236R121-E222 IonicContact CZ-OE1 3.62Å; R121-E222 IonicContact NE-OE1 2.69Å; R121-E222 PolarHBondContact NE-OE1 2.82Å; R121-E222 VanDerWaalsContact NE-OE1 3.13Å; R121-E222 IonicContact NH2-OE1 4Å; R121-E222 PolarHBondContact NH2-OE1 3.17Å; L218-E222 VanDerWaalsContact O-CB 3.25Å; L218-E222 WeakPolarHBondContact O-CB 3.2Å; L218-E222 PolarHBondContact O-N 3.33Å; H220-E222 PolarHBondContact O-N 2.65Å; E222-I225 PolarHBondContact O-N 3.47Å; E222-R226 VanDerWaalsContact O-CG 3.23Å; E222-R226 WeakPolarHBondContact O-CG 3.49Å; E222-R226 PolarHBondContact O-N 2.87Å; E222-R226 IonicContact OE2-CZ 3.32Å; E222-R226 IonicContact OE2-NE 3.23Å; E222-R226 IonicContact OE2-NH1 3.62Å; E222-R226 PolarHBondContact OE2-NH1 2.91Å; E222-R226 IonicContact OE2-NH2 3.71Å; E222-R226 PolarHBondContact OE2-NH2 2.95Å; E222-F234 HydrophobicContact CG-CD1 4.06Å; E222-F234 HydrophobicContact CG-CE1 4.27Å; E222-I236 HydrophobicContact CB-CD1 3.89Å; E222-I236 HydrophobicContact CB-CG1 4.01Å; E222-I236 HydrophobicContact CG-CG1 4.12Å; E222-I236 PolarHBondContact OE1-N 3.26Å
223N97.1Very high97.6Very high23 Ų2321.9 Ų21.912%0.12312%0.121CC..Hα-helixtrans-65.1-44.1178.3-168.564000112.8E103 L219 H220 W221 I225 R226 K227E103-N223 PolarHBondContact OE2-ND2 3.23Å; L219-N223 WeakPolarHBondContact O-CB 3.49Å; L219-N223 PolarHBondContact O-N 2.94Å; H220-N223 PolarHBondContact O-N 2.79Å; W221-N223 VanDerWaalsContact C-N 3.31Å; W221-N223 PolarHBondContact O-N 3.43Å; N223-I225 VanDerWaalsContact C-N 3.34Å; N223-I225 PolarHBondContact O-N 3.22Å; N223-R226 WeakPolarHBondContact O-CB 3.5Å; N223-R226 PolarHBondContact O-N 3.49Å; N223-K227 WeakPolarHBondContact O-CG 3.5Å; N223-K227 PolarHBondContact O-N 3.44Å
224E97.6Very high97.5Very high0 Ų022.1 Ų22.10%012%0.122CC..Hα-helixtrans-65.3-37.9178.2-68.3-56116.900111.8N147 T174 F178 H220 W221 K227 I228N147-E224 PolarHBondContact ND2-OE2 3.19Å; T174-E224 HydrophobicContact CG2-CB 3.86Å; F178-E224 HydrophobicContact CE2-CB 3.93Å; F178-E224 HydrophobicContact CE2-CG 4.01Å; F178-E224 HydrophobicContact CZ-CB 4.06Å; F178-E224 HydrophobicContact CZ-CG 3.73Å; H220-E224 IonicContact CE1-OE1 2.78Å; H220-E224 WeakPolarHBondContact O-CG 3.39Å; H220-E224 PolarHBondContact O-N 2.91Å; W221-E224 PolarHBondContact O-N 3.11Å; E224-K227 PolarHBondContact O-N 3.44Å; E224-K227 IonicContact OE1-NZ 3.64Å; E224-K227 PolarHBondContact OE1-NZ 3.18Å; E224-K227 IonicContact OE2-NZ 2.66Å; E224-I228 PolarHBondContact O-N 3.08Å; E224-I228 VanDerWaalsContact O-N 3.15Å
225I98.4Very high97.5Very high0 Ų023.1 Ų23.10%013%0.128CC..Hα-helixtrans-64.3-43172.7-67.2170.5000111.1Y138 L139 A142 W221 E222 N223 K227 I228 T229 F234Y138-I225 HydrophobicContact CD2-CG2 4.12Å; Y138-I225 HydrophobicContact CG-CG2 4.44Å; L139-I225 HydrophobicContact CD2-CD1 3.92Å; A142-I225 HydrophobicContact CB-CG1 4.27Å; W221-I225 WeakPolarHBondContact O-CG1 3.47Å; W221-I225 PolarHBondContact O-N 2.98Å; W221-I225 VanDerWaalsContact O-N 3.08Å; E222-I225 PolarHBondContact O-N 3.47Å; N223-I225 VanDerWaalsContact C-N 3.34Å; N223-I225 PolarHBondContact O-N 3.22Å; I225-K227 VanDerWaalsContact C-N 3.28Å; I225-K227 PolarHBondContact O-N 3.35Å; I225-I228 WeakPolarHBondContact O-CG1 3.42Å; I225-I228 PolarHBondContact O-N 2.63Å; I225-T229 HydrophobicContact CG2-CG2 3.99Å; I225-T229 WeakPolarHBondContact O-CB 3.26Å; I225-T229 WeakPolarHBondContact O-CG2 3.14Å; I225-T229 PolarHBondContact O-N 2.81Å; I225-T229 PolarHBondContact O-OG1 2.69Å; I225-F234 HydrophobicContact CB-CD1 4.06Å; I225-F234 HydrophobicContact CB-CE1 3.79Å; I225-F234 HydrophobicContact CD1-CE1 3.92Å; I225-F234 HydrophobicContact CD1-CZ 4.18Å; I225-F234 HydrophobicContact CG1-CE1 4.47Å; I225-F234 HydrophobicContact CG2-CD1 3.64Å; I225-F234 HydrophobicContact CG2-CE1 3.46Å; I225-F234 VanDerWaalsContact CG2-CE1 3.46Å; I225-F234 HydrophobicContact CG2-CE2 4.39Å; I225-F234 HydrophobicContact CG2-CG 4.2Å; I225-F234 HydrophobicContact CG2-CZ 3.86Å
226R97.3Very high97.5Very high16 Ų1623.1 Ų23.16%0.0613%0.128CC..Hα-helixtrans-57.5-42175.7-74.3167.8169.1160.55.4111.7E222 N223 T229 G230 D231 F232 F234E222-R226 VanDerWaalsContact O-CG 3.23Å; E222-R226 WeakPolarHBondContact O-CG 3.49Å; E222-R226 PolarHBondContact O-N 2.87Å; E222-R226 IonicContact OE2-CZ 3.32Å; E222-R226 IonicContact OE2-NE 3.23Å; E222-R226 IonicContact OE2-NH1 3.62Å; E222-R226 PolarHBondContact OE2-NH1 2.91Å; E222-R226 IonicContact OE2-NH2 3.71Å; E222-R226 PolarHBondContact OE2-NH2 2.95Å; N223-R226 WeakPolarHBondContact O-CB 3.5Å; N223-R226 PolarHBondContact O-N 3.49Å; R226-T229 PolarHBondContact O-OG1 2.86Å; R226-G230 WeakPolarHBondContact O-CA 2.92Å; R226-G230 PolarHBondContact O-N 2.91Å; R226-D231 WeakPolarHBondContact CG-O 3.31Å; R226-F232 HydrophobicContact CB-CD1 3.86Å; R226-F232 HydrophobicContact CB-CE1 4.29Å; R226-F232 PolarHBondContact NE-O 3.3Å; R226-F234 HydrophobicContact CG-CB 3.98Å; R226-F234 HydrophobicContact CG-CD1 4.32Å; R226-F234 PolarHBondContact NE-O 3.4Å; R226-F234 PolarHBondContact NH2-O 3Å
227K95.7Very high97.5Very high53 Ų5323.1 Ų23.123%0.2313%0.128CC..Hα-helixtrans-64.1-49.3-180-73.7163.961.2-179.90112E103 D149 N223 E224 I225 T229 F232E103-K227 IonicContact OE1-NZ 3.68Å; E103-K227 PolarHBondContact OE1-NZ 2.72Å; D149-K227 WeakPolarHBondContact OD2-CE 3.21Å; D149-K227 IonicContact OD2-NZ 3.38Å; D149-K227 PolarHBondContact OD2-NZ 3.02Å; N223-K227 WeakPolarHBondContact O-CG 3.5Å; N223-K227 PolarHBondContact O-N 3.44Å; E224-K227 PolarHBondContact O-N 3.44Å; E224-K227 IonicContact OE1-NZ 3.64Å; E224-K227 PolarHBondContact OE1-NZ 3.18Å; E224-K227 IonicContact OE2-NZ 2.66Å; I225-K227 VanDerWaalsContact C-N 3.28Å; I225-K227 PolarHBondContact O-N 3.35Å; K227-T229 VanDerWaalsContact C-N 3.33Å; K227-T229 PolarHBondContact O-N 2.87Å; K227-F232 HydrophobicContact CG-CE1 4.46Å
228I97.6Very high97.5Very high36 Ų3623.5 Ų23.519%0.18513%0.13CC..Hα-helixtrans-74.1-23.2-17867170000113.4L141 A142 T145 P148 T174 E224 I225L141-I228 HydrophobicContact CG-CD1 4.47Å; A142-I228 HydrophobicContact CB-CD1 3.81Å; T145-I228 HydrophobicContact CG2-CG2 4.39Å; P148-I228 HydrophobicContact CG-CG2 4.48Å; T174-I228 HydrophobicContact CG2-CD1 3.98Å; E224-I228 PolarHBondContact O-N 3.08Å; E224-I228 VanDerWaalsContact O-N 3.15Å; I225-I228 WeakPolarHBondContact O-CG1 3.42Å; I225-I228 PolarHBondContact O-N 2.63Å
229T97.8Very high97.5Very high33 Ų3323.5 Ų23.520%0.20213%0.13CC..Hα-helixtrans-92.3-24.2179.357.90000113Y138 L141 I225 R226 K227 D231Y138-T229 HydrophobicContact CD1-CG2 3.64Å; Y138-T229 HydrophobicContact CD2-CG2 3.59Å; Y138-T229 HydrophobicContact CE1-CG2 3.82Å; Y138-T229 HydrophobicContact CE2-CG2 3.79Å; Y138-T229 HydrophobicContact CG-CG2 3.52Å; L141-T229 HydrophobicContact CD2-CG2 3.89Å; I225-T229 HydrophobicContact CG2-CG2 3.99Å; I225-T229 WeakPolarHBondContact O-CB 3.26Å; I225-T229 WeakPolarHBondContact O-CG2 3.14Å; I225-T229 PolarHBondContact O-N 2.81Å; I225-T229 PolarHBondContact O-OG1 2.69Å; R226-T229 PolarHBondContact O-OG1 2.86Å; K227-T229 VanDerWaalsContact C-N 3.33Å; K227-T229 PolarHBondContact O-N 2.87Å; T229-D231 PolarHBondContact O-N 2.96Å; T229-D231 PolarHBondContact OG1-N 3.46Å
230G96.9Very high97.5Very high48 Ų4824.9 Ų24.950%0.49514%0.137SC..  trans70.4-0.4-167.200000114.1R226 F232R226-G230 WeakPolarHBondContact O-CA 2.92Å; R226-G230 PolarHBondContact O-N 2.91Å; G230-F232 PolarHBondContact O-N 2.62Å
231D97.4Very high97.5Very high28 Ų2824.6 Ų24.615%0.1514%0.136CC..  trans-8983.6175.3-179.310.3000109.9K134 Y138 R226 T229 N233 F234K134-D231 IonicContact NZ-OD2 3.88Å; K134-D231 PolarHBondContact NZ-OD2 3.18Å; Y138-D231 HydrophobicContact CE2-CB 3.79Å; Y138-D231 VanDerWaalsContact OH-CB 3.26Å; Y138-D231 WeakPolarHBondContact OH-CB 3.39Å; Y138-D231 PolarHBondContact OH-OD2 3.23Å; R226-D231 WeakPolarHBondContact CG-O 3.31Å; T229-D231 PolarHBondContact O-N 2.96Å; T229-D231 PolarHBondContact OG1-N 3.46Å; D231-N233 PolarHBondContact O-N 3.28Å; D231-N233 VanDerWaalsContact O-N 3.11Å; D231-N233 WeakPolarHBondContact OD1-CB 3.19Å; D231-N233 PolarHBondContact OD1-N 2.92Å; D231-F234 HydrophobicContact CB-CB 4.48Å; D231-F234 WeakPolarHBondContact O-CB 3.44Å; D231-F234 PolarHBondContact O-N 3.4Å; D231-F234 PolarHBondContact OD1-N 2.97Å
232F94.2Very high97.4Very high95 Ų9527.1 Ų27.142%0.41715%0.145SC..THydrogen-bonded Turntrans-66.8-7.6177.4-69.2-71.3000114W109 R117 R226 K227 G230W109-F232 HydrophobicContact CH2-CB 4.16Å; W109-F232 HydrophobicContact CH2-CD1 4.34Å; W109-F232 WeakPolarHBondContact CH2-O 3.24Å; W109-F232 HydrophobicContact CZ3-CB 3.69Å; W109-F232 AromaticContact CZ3-CD1 3.65Å; W109-F232 HydrophobicContact CZ3-CD1 3.65Å; W109-F232 AromaticContact CZ3-CG 3.97Å; W109-F232 HydrophobicContact CZ3-CG 3.97Å; R117-F232 PolarHBondContact NH2-O 2.96Å; R226-F232 HydrophobicContact CB-CD1 3.86Å; R226-F232 HydrophobicContact CB-CE1 4.29Å; R226-F232 PolarHBondContact NE-O 3.3Å; K227-F232 HydrophobicContact CG-CE1 4.46Å; G230-F232 PolarHBondContact O-N 2.62Å
233N94.3Very high97.3Very high108 Ų10830.9 Ų30.958%0.57817%0.166SC*.THydrogen-bonded Turntrans-89.1-5.5172.4-64-29.4000112.8R117 D231 T235R117-N233 PolarHBondContact NH1-OD1 3.43Å; D231-N233 PolarHBondContact O-N 3.28Å; D231-N233 VanDerWaalsContact O-N 3.11Å; D231-N233 WeakPolarHBondContact OD1-CB 3.19Å; D231-N233 PolarHBondContact OD1-N 2.92Å; N233-T235 PolarHBondContact O-N 3.28Å
234F97.5Very high97.2Very high5 Ų530 Ų302%0.02216%0.162CC..  trans-55.3137.5177174.6-103.7000111.4F135 Y138 E222 I225 R226 D231 I236F135-F234 AromaticContact CD2-CE2 3.76Å; F135-F234 HydrophobicContact CD2-CE2 3.76Å; F135-F234 AromaticContact CD2-CZ 3.79Å; F135-F234 HydrophobicContact CD2-CZ 3.79Å; F135-F234 HydrophobicContact CE2-CE2 4.46Å; F135-F234 HydrophobicContact CE2-CZ 4.04Å; Y138-F234 HydrophobicContact CD2-CB 4.48Å; Y138-F234 AromaticContact CD2-CD2 3.42Å; Y138-F234 HydrophobicContact CD2-CD2 3.42Å; Y138-F234 VanDerWaalsContact CD2-CD2 3.42Å; Y138-F234 AromaticContact CD2-CE2 3.72Å; Y138-F234 HydrophobicContact CD2-CE2 3.72Å; Y138-F234 HydrophobicContact CD2-CG 4.01Å; Y138-F234 HydrophobicContact CE2-CB 4.3Å; Y138-F234 AromaticContact CE2-CD2 3.87Å; Y138-F234 HydrophobicContact CE2-CD2 3.87Å; Y138-F234 HydrophobicContact CE2-CG 4.31Å; E222-F234 HydrophobicContact CG-CD1 4.06Å; E222-F234 HydrophobicContact CG-CE1 4.27Å; I225-F234 HydrophobicContact CB-CD1 4.06Å; I225-F234 HydrophobicContact CB-CE1 3.79Å; I225-F234 HydrophobicContact CD1-CE1 3.92Å; I225-F234 HydrophobicContact CD1-CZ 4.18Å; I225-F234 HydrophobicContact CG1-CE1 4.47Å; I225-F234 HydrophobicContact CG2-CD1 3.64Å; I225-F234 HydrophobicContact CG2-CE1 3.46Å; I225-F234 VanDerWaalsContact CG2-CE1 3.46Å; I225-F234 HydrophobicContact CG2-CE2 4.39Å; I225-F234 HydrophobicContact CG2-CG 4.2Å; I225-F234 HydrophobicContact CG2-CZ 3.86Å; R226-F234 HydrophobicContact CG-CB 3.98Å; R226-F234 HydrophobicContact CG-CD1 4.32Å; R226-F234 PolarHBondContact NE-O 3.4Å; R226-F234 PolarHBondContact NH2-O 3Å; D231-F234 HydrophobicContact CB-CB 4.48Å; D231-F234 WeakPolarHBondContact O-CB 3.44Å; D231-F234 PolarHBondContact O-N 3.4Å; D231-F234 PolarHBondContact OD1-N 2.97Å; F234-I236 HydrophobicContact CE1-CG1 4.07Å; F234-I236 HydrophobicContact CZ-CG1 4.4Å
235T97.9Very high97Very high26 Ų2638 Ų3816%0.1620%0.199CC..  trans-134.5147.917156.50000109.9S119 V120 N233 P237S119-T235 VanDerWaalsContact CB-CG2 3.46Å; V120-T235 PolarHBondContact O-OG1 2.87Å; N233-T235 PolarHBondContact O-N 3.28Å; T235-P237 WeakPolarHBondContact O-CD 3.35Å
236I98.6Very high96.9Very high0 Ų041.3 Ų41.30%022%0.222CC..  trans-75119.8172.4-62.1177.8000108.2R121 L218 W221 E222 F234 L390 A394R121-I236 VanDerWaalsContact CD-O 3.28Å; R121-I236 WeakPolarHBondContact CD-O 3.29Å; R121-I236 WeakPolarHBondContact CG-O 3.45Å; L218-I236 HydrophobicContact CD2-CD1 4.22Å; W221-I236 HydrophobicContact CB-CD1 4.31Å; E222-I236 HydrophobicContact CB-CD1 3.89Å; E222-I236 HydrophobicContact CB-CG1 4.01Å; E222-I236 HydrophobicContact CG-CG1 4.12Å; E222-I236 PolarHBondContact OE1-N 3.26Å; F234-I236 HydrophobicContact CE1-CG1 4.07Å; F234-I236 HydrophobicContact CZ-CG1 4.4Å; I236-L390 HydrophobicContact CD1-CD2 3.78Å; I236-L390 HydrophobicContact CG2-CB 3.96Å; I236-L390 HydrophobicContact CG2-CD2 4.36Å; I236-A394 HydrophobicContact CG2-CB 4.21Å
237P98.8Very high96.9Very high1 Ų141.4 Ų41.41%0.00623%0.225CC..  trans-76.3167.4176.133.3-32.2000111R122 I124 M127 F135 T235 L391 A394R122-P237 VanDerWaalsContact O-CA 3.28Å; R122-P237 WeakPolarHBondContact O-CA 3.16Å; R122-P237 VanDerWaalsContact O-CB 3.22Å; R122-P237 WeakPolarHBondContact O-CB 3.03Å; I124-P237 HydrophobicContact CB-CB 4.14Å; I124-P237 HydrophobicContact CB-CG 4.33Å; I124-P237 HydrophobicContact CD1-CG 4.23Å; I124-P237 HydrophobicContact CG1-CG 4.4Å; M127-P237 HydrophobicContact CE-CB 4.34Å; M127-P237 HydrophobicContact SD-CB 3.5Å; M127-P237 VanDerWaalsContact SD-CB 3.5Å; M127-P237 HydrophobicContact SD-CG 4.16Å; F135-P237 HydrophobicContact CD1-CG 4.18Å; F135-P237 HydrophobicContact CD2-CG 3.89Å; F135-P237 HydrophobicContact CE1-CG 4.25Å; F135-P237 HydrophobicContact CE2-CG 4Å; F135-P237 HydrophobicContact CG-CG 4Å; F135-P237 HydrophobicContact CZ-CG 4.15Å; T235-P237 WeakPolarHBondContact O-CD 3.35Å; P237-L391 HydrophobicContact CB-CD2 4.43Å; P237-L391 HydrophobicContact CG-CD2 3.74Å; P237-L391 WeakPolarHBondContact O-CD2 3.02Å; P237-A394 WeakPolarHBondContact O-CB 3.34Å
238Y98.8Very high97Very high8 Ų843 Ų433%0.03123%0.233CC..BIsolated β-bridgetrans-114.4156.7175.264.8-89.4000111.2R121 R122 N123 I124 D240 F395 Y452 Y454R121-Y238 HydrophobicContact CB-CD1 4.46Å; R121-Y238 WeakPolarHBondContact O-CE1 3.48Å; R122-Y238 VanDerWaalsContact C-CD1 3.49Å; R122-Y238 VanDerWaalsContact O-CD1 3.28Å; R122-Y238 WeakPolarHBondContact O-CD1 3.45Å; R122-Y238 PolarHBondContact O-N 3.48Å; N123-Y238 WeakPolarHBondContact CA-O 3.33Å; N123-Y238 HydrophobicContact CB-CD2 4.24Å; N123-Y238 HydrophobicContact CB-CE1 4.31Å; N123-Y238 HydrophobicContact CB-CE2 3.55Å; N123-Y238 VanDerWaalsContact N-CE1 3.27Å; I124-Y238 PolarHBondContact N-O 3.27Å; Y238-D240 HydrophobicContact CD2-CB 4.32Å; Y238-D240 HydrophobicContact CE2-CB 4.12Å; Y238-F395 AromaticContact CD2-CD2 3.57Å; Y238-F395 HydrophobicContact CD2-CD2 3.57Å; Y238-F395 HydrophobicContact CD2-CE2 4.26Å; Y238-F395 HydrophobicContact CD2-CG 4.47Å; Y238-F395 HydrophobicContact CE2-CD2 4.15Å; Y238-F395 HydrophobicContact CE2-CE2 4.42Å; Y238-F395 HydrophobicContact CG-CD2 4.33Å; Y238-Y452 AromaticContact CD1-CD1 3.53Å; Y238-Y452 HydrophobicContact CD1-CD1 3.53Å; Y238-Y452 AromaticContact CD1-CE1 3.87Å; Y238-Y452 HydrophobicContact CD1-CE1 3.87Å; Y238-Y452 AromaticContact CE1-CD1 3.79Å; Y238-Y452 HydrophobicContact CE1-CD1 3.79Å; Y238-Y452 HydrophobicContact CG-CD1 4.33Å; Y238-Y452 HydrophobicContact CG-CE1 4.4Å; Y238-Y454 HydrophobicContact CE1-CD1 4.32Å; Y238-Y454 HydrophobicContact CE2-CD1 4.11Å; Y238-Y454 HydrophobicContact CE2-CE1 4.34Å; Y238-Y454 AromaticContact CZ-CD1 3.66Å; Y238-Y454 VanDerWaalsContact OH-CD1 3.32Å; Y238-Y454 WeakPolarHBondContact OH-CD1 3.27Å
239W98.5Very high97.1Very high0 Ų041.3 Ų41.30%022%0.224CC..  trans-108.4112.6164.917031.3000108.9I124 W241 A244 E248 V249 L369 M373 I388 L391 F395I124-W239 HydrophobicContact CG2-CB 4.31Å; W239-W241 HydrophobicContact CD2-CB 3.96Å; W239-W241 HydrophobicContact CE3-CB 4.32Å; W239-W241 HydrophobicContact CG-CB 4.47Å; W239-W241 HydrophobicContact CH2-CB 4.22Å; W239-W241 HydrophobicContact CZ2-CB 3.84Å; W239-W241 HydrophobicContact CZ3-CB 4.45Å; W239-W241 VanDerWaalsContact O-CD1 3.26Å; W239-W241 PolarHBondContact O-N 3.33Å; W239-A244 HydrophobicContact CZ2-CB 4.26Å; W239-E248 PolarHBondContact NE1-OE2 3.42Å; W239-V249 HydrophobicContact CB-CG1 4.07Å; W239-V249 HydrophobicContact CD2-CG1 3.85Å; W239-V249 HydrophobicContact CD2-CG2 3.95Å; W239-V249 HydrophobicContact CE3-CG1 4.4Å; W239-V249 HydrophobicContact CE3-CG2 3.68Å; W239-V249 HydrophobicContact CG-CG1 3.67Å; W239-V249 HydrophobicContact CH2-CG2 4.4Å; W239-V249 HydrophobicContact CZ3-CG2 3.92Å; W239-L369 HydrophobicContact CE3-CD2 4.2Å; W239-L369 HydrophobicContact CH2-CD1 3.89Å; W239-L369 HydrophobicContact CZ3-CD1 3.88Å; W239-L369 HydrophobicContact CZ3-CD2 3.82Å; W239-L369 HydrophobicContact CZ3-CG 4.36Å; W239-M373 HydrophobicContact CH2-CE 3.74Å; W239-M373 HydrophobicContact CZ3-CE 3.45Å; W239-M373 VanDerWaalsContact CZ3-CE 3.45Å; W239-I388 HydrophobicContact CE3-CG2 4.24Å; W239-I388 HydrophobicContact CZ3-CG2 4.16Å; W239-L391 HydrophobicContact CB-CB 3.83Å; W239-L391 HydrophobicContact CB-CD1 4.19Å; W239-L391 PolarHBondContact N-O 3.45Å; W239-L391 VanDerWaalsContact N-O 3.15Å; W239-F395 WeakPolarHBondContact O-CB 3.38Å; W239-F395 WeakPolarHBondContact O-CG 3.27Å
240D98.1Very high97.1Very high35 Ų3540.9 Ų40.919%0.18722%0.223CC..  trans-73.592.2169.9-173.2-7.5000109.3N123 Y238 R242 F395N123-D240 WeakPolarHBondContact ND2-CB 3.15Å; Y238-D240 HydrophobicContact CD2-CB 4.32Å; Y238-D240 HydrophobicContact CE2-CB 4.12Å; D240-R242 VanDerWaalsContact C-N 3.26Å; D240-R242 PolarHBondContact O-N 3.25Å; D240-R242 WeakPolarHBondContact OD1-CB 3.38Å; D240-R242 VanDerWaalsContact OD1-CG 3.31Å; D240-R242 WeakPolarHBondContact OD1-CG 3.02Å; D240-R242 IonicContact OD1-CZ 2.75Å; D240-R242 PolarHBondContact OD1-N 3.05Å; D240-R242 IonicContact OD1-NE 2.73Å; D240-R242 PolarHBondContact OD1-NE 3.3Å; D240-R242 IonicContact OD1-NH2 2.7Å; D240-R242 IonicContact OD2-CZ 2.79Å; D240-R242 IonicContact OD2-NE 3.17Å; D240-R242 PolarHBondContact OD2-NE 2.98Å; D240-R242 IonicContact OD2-NH2 2.84Å; D240-R242 PolarHBondContact OD2-NH2 3.3Å; D240-F395 HydrophobicContact CB-CD2 4.26Å; D240-F395 HydrophobicContact CB-CE2 3.81Å; D240-F395 HydrophobicContact CB-CZ 4.17Å; D240-F395 WeakPolarHBondContact OD1-CZ 3.45Å
241W97.4Very high97.1Very high0 Ų041.5 Ų41.50%022%0.217CC..  trans-84.34.9-17847.3-105.7000113.2W239 N243 A244 P316 V321 M365 L369 H392 F395 I396 I399W239-W241 HydrophobicContact CD2-CB 3.96Å; W239-W241 HydrophobicContact CE3-CB 4.32Å; W239-W241 HydrophobicContact CG-CB 4.47Å; W239-W241 HydrophobicContact CH2-CB 4.22Å; W239-W241 HydrophobicContact CZ2-CB 3.84Å; W239-W241 HydrophobicContact CZ3-CB 4.45Å; W239-W241 VanDerWaalsContact O-CD1 3.26Å; W239-W241 PolarHBondContact O-N 3.33Å; W241-N243 PolarHBondContact O-N 3.09Å; W241-A244 HydrophobicContact CB-CB 4.48Å; W241-A244 WeakPolarHBondContact O-CB 3.45Å; W241-A244 PolarHBondContact O-N 3.4Å; W241-P316 HydrophobicContact CE3-CB 4.28Å; W241-P316 HydrophobicContact CE3-CG 3.88Å; W241-P316 HydrophobicContact CH2-CB 4.04Å; W241-P316 HydrophobicContact CH2-CG 3.72Å; W241-P316 HydrophobicContact CZ3-CB 3.45Å; W241-P316 VanDerWaalsContact CZ3-CB 3.45Å; W241-P316 HydrophobicContact CZ3-CG 3.3Å; W241-V321 HydrophobicContact CH2-CG2 4.34Å; W241-V321 HydrophobicContact CZ3-CG2 4.41Å; W241-M365 HydrophobicContact CH2-CE 4.47Å; W241-L369 HydrophobicContact CB-CD1 4.44Å; W241-L369 HydrophobicContact CG-CD1 4.44Å; W241-L369 HydrophobicContact CG-CD2 4.15Å; W241-H392 AromaticContact CD1-ND1 3.76Å; W241-H392 AromaticContact CE2-ND1 3.98Å; W241-H392 AromaticContact NE1-CE1 3.6Å; W241-H392 AromaticContact NE1-ND1 3.11Å; W241-H392 PolarHBondContact NE1-ND1 2.73Å; W241-H392 VanDerWaalsContact NE1-ND1 3.11Å; W241-F395 AromaticContact CD1-CD1 3.86Å; W241-F395 HydrophobicContact CD2-CD1 4.06Å; W241-F395 HydrophobicContact CD2-CE1 4.13Å; W241-F395 AromaticContact CE2-CD1 3.47Å; W241-F395 VanDerWaalsContact CE2-CD1 3.47Å; W241-F395 AromaticContact CE2-CE1 3.87Å; W241-F395 HydrophobicContact CE3-CE1 4.43Å; W241-F395 HydrophobicContact CG-CD1 4.32Å; W241-F395 HydrophobicContact CH2-CD1 4.47Å; W241-F395 HydrophobicContact CH2-CE1 4.26Å; W241-F395 AromaticContact CZ2-CD1 3.76Å; W241-F395 HydrophobicContact CZ2-CD1 3.76Å; W241-F395 AromaticContact CZ2-CE1 3.99Å; W241-F395 HydrophobicContact CZ2-CE1 3.99Å; W241-F395 HydrophobicContact CZ3-CE1 4.42Å; W241-F395 AromaticContact NE1-CD1 3.35Å; W241-I396 HydrophobicContact CZ2-CD1 3.82Å; W241-I399 HydrophobicContact CH2-CD1 4.42Å; W241-I399 HydrophobicContact CZ2-CD1 4.41Å
242R96.4Very high97.2Very high53 Ų5343.5 Ų43.520%0.223%0.228CC..THydrogen-bonded Turntrans-59.1128.2-178.5-69.1177.2-65.3-177.9-3.4110.5D240 A244 V321 F395D240-R242 VanDerWaalsContact C-N 3.26Å; D240-R242 PolarHBondContact O-N 3.25Å; D240-R242 WeakPolarHBondContact OD1-CB 3.38Å; D240-R242 VanDerWaalsContact OD1-CG 3.31Å; D240-R242 WeakPolarHBondContact OD1-CG 3.02Å; D240-R242 IonicContact OD1-CZ 2.75Å; D240-R242 PolarHBondContact OD1-N 3.05Å; D240-R242 IonicContact OD1-NE 2.73Å; D240-R242 PolarHBondContact OD1-NE 3.3Å; D240-R242 IonicContact OD1-NH2 2.7Å; D240-R242 IonicContact OD2-CZ 2.79Å; D240-R242 IonicContact OD2-NE 3.17Å; D240-R242 PolarHBondContact OD2-NE 2.98Å; D240-R242 IonicContact OD2-NH2 2.84Å; D240-R242 PolarHBondContact OD2-NH2 3.3Å; R242-A244 PolarHBondContact O-N 3.11Å; R242-V321 HydrophobicContact CG-CG2 3.89Å; R242-F395 HydrophobicContact CG-CE1 3.88Å; R242-F395 HydrophobicContact CG-CZ 3.79Å
243N97Very high97.3Very high81 Ų8142.2 Ų42.243%0.43323%0.234SC..THydrogen-bonded Turntrans65.48.3-178.6-38.5-66.6000114.4W241 Q245 P316 T317 T318W241-N243 PolarHBondContact O-N 3.09Å; N243-Q245 PolarHBondContact O-N 3.21Å; N243-Q245 PolarHBondContact O-NE2 2.88Å; N243-P316 PolarHBondContact N-O 3.46Å; N243-T317 VanDerWaalsContact OD1-CA 3.25Å; N243-T317 WeakPolarHBondContact OD1-CA 2.97Å; N243-T317 VanDerWaalsContact OD1-CB 3.28Å; N243-T317 WeakPolarHBondContact OD1-CB 3.17Å; N243-T318 PolarHBondContact ND2-OG1 2.73Å; N243-T318 PolarHBondContact OD1-N 3.4Å
244A96.1Very high97.4Very high5 Ų537.5 Ų37.54%0.04121%0.209CC..  trans-60.7137.817400000110W239 W241 R242 L315W239-A244 HydrophobicContact CZ2-CB 4.26Å; W241-A244 HydrophobicContact CB-CB 4.48Å; W241-A244 WeakPolarHBondContact O-CB 3.45Å; W241-A244 PolarHBondContact O-N 3.4Å; R242-A244 PolarHBondContact O-N 3.11Å; A244-L315 HydrophobicContact CB-CD1 4.22Å; A244-L315 WeakPolarHBondContact O-CB 3.36Å; A244-L315 WeakPolarHBondContact O-CD1 3.25Å
245Q93.3Very high97.5Very high167 Ų16737.3 Ų37.378%0.7821%0.208SC*.SBendtrans-104-11.6175.7-59.8-59.6-44.600112.1N243N243-Q245 PolarHBondContact O-N 3.21Å; N243-Q245 PolarHBondContact O-NE2 2.88Å
246S95.9Very high97.5Very high69 Ų6936 Ų3648%0.48320%0.201SC..SBendtrans-151169-176.556.70000110E248S246-E248 PolarHBondContact O-N 2.84Å
247C97.4Very high97.4Very high18 Ų1836.5 Ų36.512%0.12221%0.205CC..  trans-74.994.2171-177.70000110.9V249 C250 P304 F372 M373C247-V249 VanDerWaalsContact C-N 3.3Å; C247-V249 PolarHBondContact O-N 2.98Å; C247-C250 HydrophobicContact CB-CB 3.64Å; C247-C250 WeakPolarHBondContact CB-SG 3.46Å; C247-C250 WeakPolarHBondContact O-CB 3.33Å; C247-C250 PolarHBondContact O-N 3.44Å; C247-C250 WeakPolarHBondContact SG-CB 3.44Å; C247-C250 PolarHBondContact SG-N 2.89Å; C247-C250 CovalentContact SG-SG 2.03Å; C247-C250 PolarHBondContact SG-SG 3.07Å; C247-P304 HydrophobicContact CB-CB 3.8Å; C247-P304 HydrophobicContact CB-CG 3.94Å; C247-F372 HydrophobicContact CB-CE1 4.26Å; C247-M373 HydrophobicContact CB-CE 4.32Å
248E97.5Very high97.4Very high87 Ų8743 Ų4341%0.40723%0.23SC..THydrogen-bonded Turntrans-68.3-28.9-178.7-62.8169.5117.500112.9M125 W239 S246 C250M125-E248 HydrophobicContact CE-CB 3.96Å; M125-E248 HydrophobicContact SD-CB 4.5Å; W239-E248 PolarHBondContact NE1-OE2 3.42Å; S246-E248 PolarHBondContact O-N 2.84Å; E248-C250 VanDerWaalsContact C-N 3.32Å
249V98.4Very high97.3Very high0 Ų043.6 Ų43.60%023%0.233CC..THydrogen-bonded Turntrans-82.1-7.9177.1-61.80000113.4I124 M125 W239 C247 T251 L254 M255 I388 L391I124-V249 HydrophobicContact CG2-CG1 3.86Å; M125-V249 HydrophobicContact SD-CG1 3.72Å; W239-V249 HydrophobicContact CB-CG1 4.07Å; W239-V249 HydrophobicContact CD2-CG1 3.85Å; W239-V249 HydrophobicContact CD2-CG2 3.95Å; W239-V249 HydrophobicContact CE3-CG1 4.4Å; W239-V249 HydrophobicContact CE3-CG2 3.68Å; W239-V249 HydrophobicContact CG-CG1 3.67Å; W239-V249 HydrophobicContact CH2-CG2 4.4Å; W239-V249 HydrophobicContact CZ3-CG2 3.92Å; C247-V249 VanDerWaalsContact C-N 3.3Å; C247-V249 PolarHBondContact O-N 2.98Å; V249-T251 PolarHBondContact O-N 3.01Å; V249-L254 HydrophobicContact CB-CD1 4.46Å; V249-L254 HydrophobicContact CG1-CD1 4.47Å; V249-L254 VanDerWaalsContact O-CB 3.29Å; V249-L254 WeakPolarHBondContact O-CB 3.34Å; V249-M255 HydrophobicContact CB-CG 4.03Å; V249-M255 HydrophobicContact CG2-CB 4.49Å; V249-M255 HydrophobicContact CG2-CG 4.13Å; V249-M255 WeakPolarHBondContact O-CB 3.47Å; V249-M255 PolarHBondContact O-N 3.21Å; V249-I388 HydrophobicContact CG2-CD1 3.98Å; V249-I388 HydrophobicContact CG2-CG1 4.15Å; V249-L391 HydrophobicContact CB-CD1 4.27Å; V249-L391 HydrophobicContact CG1-CD1 4.08Å; V249-L391 HydrophobicContact CG2-CD1 4.28Å
250C98.3Very high97.2Very high25 Ų2549.2 Ų49.217%0.16927%0.273CS..  trans-82.265.4179.8-67.60000111.4C247 E248 G256 G257C247-C250 HydrophobicContact CB-CB 3.64Å; C247-C250 WeakPolarHBondContact CB-SG 3.46Å; C247-C250 WeakPolarHBondContact O-CB 3.33Å; C247-C250 PolarHBondContact O-N 3.44Å; C247-C250 WeakPolarHBondContact SG-CB 3.44Å; C247-C250 PolarHBondContact SG-N 2.89Å; C247-C250 CovalentContact SG-SG 2.03Å; C247-C250 PolarHBondContact SG-SG 3.07Å; E248-C250 VanDerWaalsContact C-N 3.32Å; C250-G256 CarbonylContact C-O 3.16Å; C250-G256 WeakPolarHBondContact CA-O 3.14Å; C250-G257 WeakPolarHBondContact O-CA 3.44Å
251T98.1Very high97.1Very high60 Ų6055.3 Ų55.337%0.36830%0.304SS..SBendtrans-128.1156.7174.9690000110.1V249 A253 L254 M255 G256V249-T251 PolarHBondContact O-N 3.01Å; T251-A253 PolarHBondContact O-N 3.4Å; T251-L254 CarbonylContact O-C 3.48Å; T251-L254 PolarHBondContact O-N 2.75Å; T251-L254 PolarHBondContact OG1-N 3.46Å; T251-M255 PolarHBondContact O-N 2.71Å; T251-G256 CarbonylContact O-C 3.22Å; T251-G256 VanDerWaalsContact O-CA 3.26Å; T251-G256 WeakPolarHBondContact O-CA 3.45Å; T251-G256 PolarHBondContact O-N 3.11Å
252D97.8Very high97.1Very high71 Ų7158.2 Ų58.238%0.3832%0.32SS..THydrogen-bonded Turntrans-65.8-19.8179.6-70-21.9000113.4L254 G257 S267 A269D252-L254 VanDerWaalsContact C-N 3.34Å; D252-G257 WeakPolarHBondContact OD1-CA 3.37Å; D252-G257 PolarHBondContact OD1-N 3.25Å; D252-S267 WeakPolarHBondContact OD1-CB 3.43Å; D252-S267 PolarHBondContact OD1-OG 2.82Å; D252-S267 PolarHBondContact OD2-OG 2.82Å; D252-A269 HydrophobicContact CB-CB 4.21Å; D252-A269 WeakPolarHBondContact OD2-CB 3.34Å
253A96.4Very high97.1Very high67 Ų6758.6 Ų58.655%0.55433%0.329SS*.THydrogen-bonded Turntrans-77.6-18.8171.700000113.4I136 T251I136-A253 WeakPolarHBondContact CD1-O 3.41Å; T251-A253 PolarHBondContact O-N 3.4Å
254L98Very high97.1Very high10 Ų1058.1 Ų58.15%0.05233%0.326CS..THydrogen-bonded Turntrans-122-114.8-177.5-67.9178.3000110.7I124 M125 Q132 I136 V249 T251 D252 G256 F272I124-L254 HydrophobicContact CD1-CD2 4.01Å; I124-L254 HydrophobicContact CG1-CD2 4.07Å; M125-L254 HydrophobicContact SD-CD1 4.02Å; Q132-L254 HydrophobicContact CB-CD2 3.93Å; Q132-L254 HydrophobicContact CG-CD2 3.8Å; I136-L254 WeakPolarHBondContact CD1-O 3.42Å; V249-L254 HydrophobicContact CB-CD1 4.46Å; V249-L254 HydrophobicContact CG1-CD1 4.47Å; V249-L254 VanDerWaalsContact O-CB 3.29Å; V249-L254 WeakPolarHBondContact O-CB 3.34Å; T251-L254 CarbonylContact O-C 3.48Å; T251-L254 PolarHBondContact O-N 2.75Å; T251-L254 PolarHBondContact OG1-N 3.46Å; D252-L254 VanDerWaalsContact C-N 3.34Å; L254-G256 PolarHBondContact O-N 2.99Å; L254-F272 WeakPolarHBondContact O-CE2 3.39Å
255M98.3Very high97.3Very high0 Ų060 Ų600%034%0.336CS..THydrogen-bonded Turntrans-85.511.4-169.5-56.8-57.9141.500113.9I124 F135 I136 V249 T251 F272 R302 P387 I388 L391I124-M255 HydrophobicContact CD1-CE 3.24Å; F135-M255 HydrophobicContact CD1-CE 3.71Å; F135-M255 HydrophobicContact CE1-CE 3.46Å; F135-M255 VanDerWaalsContact CE1-CE 3.46Å; F135-M255 HydrophobicContact CE1-SD 4.32Å; I136-M255 HydrophobicContact CG1-CE 4.49Å; V249-M255 HydrophobicContact CB-CG 4.03Å; V249-M255 HydrophobicContact CG2-CB 4.49Å; V249-M255 HydrophobicContact CG2-CG 4.13Å; V249-M255 WeakPolarHBondContact O-CB 3.47Å; V249-M255 PolarHBondContact O-N 3.21Å; T251-M255 PolarHBondContact O-N 2.71Å; M255-F272 HydrophobicContact SD-CE2 4.19Å; M255-F272 HydrophobicContact SD-CZ 4.43Å; M255-R302 PolarHBondContact O-NH1 2.9Å; M255-R302 PolarHBondContact O-NH2 3.5Å; M255-P387 HydrophobicContact SD-CB 4.21Å; M255-P387 HydrophobicContact SD-CG 4.34Å; M255-I388 HydrophobicContact CB-CD1 4.11Å; M255-I388 HydrophobicContact CB-CG1 3.71Å; M255-I388 HydrophobicContact CG-CG1 3.85Å; M255-L391 HydrophobicContact CE-CD1 3.76Å; M255-L391 HydrophobicContact CE-CD2 4.4Å; M255-L391 HydrophobicContact CE-CG 4.36Å; M255-L391 HydrophobicContact CG-CD1 3.81Å; M255-L391 HydrophobicContact SD-CD1 4.11Å
256G98.1Very high97.5Very high0 Ų052.4 Ų52.40%030%0.3CS..  trans90.7130.4-177.500000112.9C250 T251 L254 S270 R302C250-G256 CarbonylContact C-O 3.16Å; C250-G256 WeakPolarHBondContact CA-O 3.14Å; T251-G256 CarbonylContact O-C 3.22Å; T251-G256 VanDerWaalsContact O-CA 3.26Å; T251-G256 WeakPolarHBondContact O-CA 3.45Å; T251-G256 PolarHBondContact O-N 3.11Å; L254-G256 PolarHBondContact O-N 2.99Å; G256-S270 VanDerWaalsContact CA-CB 3.47Å; G256-S270 VanDerWaalsContact CA-OG 3.27Å; G256-S270 WeakPolarHBondContact CA-OG 3.14Å; G256-R302 PolarHBondContact O-NH1 3.4Å
257G97.6Very high97.6Very high9 Ų949.8 Ų49.89%0.09328%0.282CS..  trans-77174.1176.200000112.8C250 D252 I266 S267C250-G257 WeakPolarHBondContact O-CA 3.44Å; D252-G257 WeakPolarHBondContact OD1-CA 3.37Å; D252-G257 PolarHBondContact OD1-N 3.25Å; G257-I266 CarbonylContact O-C 3.45Å; G257-I266 WeakPolarHBondContact O-CA 3.3Å; G257-S267 WeakPolarHBondContact O-CB 3.11Å; G257-S267 PolarHBondContact O-N 2.99Å
258R97.4Very high97.7Very high139 Ų13953.7 Ų53.753%0.52531%0.307SS..BIsolated β-bridgetrans-73.7133.9173.7-178.9179.7-80161.6-0.6110.3P263 N303 P304R258-P263 HydrophobicContact CG-CB 4.34Å; R258-N303 PolarHBondContact NH2-OD1 2.89Å; R258-P304 PolarHBondContact NH2-O 3.42Å; R258-P304 VanDerWaalsContact NH2-O 3.12Å
259N97.8Very high97.7Very high20 Ų2053.2 Ų53.211%0.10732%0.318CS..  trans-68.5134.6172.4-177.3-54.5000111L261 N262 L265 P268N259-L261 VanDerWaalsContact C-N 3.35Å; N259-L261 PolarHBondContact O-N 3.48Å; N259-L261 WeakPolarHBondContact OD1-CA 3.47Å; N259-L261 WeakPolarHBondContact OD1-CB 3.31Å; N259-L261 PolarHBondContact OD1-N 3.48Å; N259-N262 WeakPolarHBondContact CB-O 3.49Å; N259-N262 CarbonylContact O-C 3.34Å; N259-N262 PolarHBondContact OD1-N 3.37Å; N259-N262 VanDerWaalsContact OD1-N 3.12Å; N259-L265 HydrophobicContact CB-CB 4.01Å; N259-L265 WeakPolarHBondContact CB-O 3.38Å; N259-L265 PolarHBondContact N-O 2.62Å; N259-P268 WeakPolarHBondContact ND2-CD 3.41Å
260S96Very high97.7Very high118 Ų11853.5 Ų53.583%0.82532%0.32SS*.SBendtrans-72.1-23.9-176.155.40000114.4
261L96.6Very high97.6Very high163 Ų16355.1 Ų55.185%0.85333%0.329SS*.SBendtrans-95-33.2-178.8-60.1177.3000112.5N259N259-L261 VanDerWaalsContact C-N 3.35Å; N259-L261 PolarHBondContact O-N 3.48Å; N259-L261 WeakPolarHBondContact OD1-CA 3.47Å; N259-L261 WeakPolarHBondContact OD1-CB 3.31Å; N259-L261 PolarHBondContact OD1-N 3.48Å
262N97.4Very high97.7Very high61 Ų6152.2 Ų52.233%0.32631%0.311SS..  trans-135.6107.4177.3-176.5-16.8000110.3N259 N264 L265N259-N262 WeakPolarHBondContact CB-O 3.49Å; N259-N262 CarbonylContact O-C 3.34Å; N259-N262 PolarHBondContact OD1-N 3.37Å; N259-N262 VanDerWaalsContact OD1-N 3.12Å; N262-N264 PolarHBondContact O-N 2.94Å; N262-N264 WeakPolarHBondContact OD1-CB 3.29Å; N262-N264 PolarHBondContact OD1-N 2.99Å; N262-L265 HydrophobicContact CB-CB 4.41Å; N262-L265 HydrophobicContact CB-CD1 3.97Å; N262-L265 HydrophobicContact CB-CG 4.09Å; N262-L265 PolarHBondContact O-N 2.83Å
263P96.1Very high97.7Very high61 Ų6150.8 Ų50.840%0.39631%0.307SS..THydrogen-bonded Turntrans-67.2-10.2-173.628.5-36.5000114.7R258 R302R258-P263 HydrophobicContact CG-CB 4.34Å; P263-R302 VanDerWaalsContact O-O 3.12Å
264N97.6Very high97.7Very high70 Ų7051.5 Ų51.537%0.37431%0.308SS..THydrogen-bonded Turntrans-88.3-6.6175.1-60.5-36.3000113.2N262 L301 R302 N303N262-N264 PolarHBondContact O-N 2.94Å; N262-N264 WeakPolarHBondContact OD1-CB 3.29Å; N262-N264 PolarHBondContact OD1-N 2.99Å; N264-L301 WeakPolarHBondContact O-CA 3.36Å; N264-R302 CarbonylContact C-O 3.27Å; N264-R302 PolarHBondContact O-N 3.41Å; N264-N303 WeakPolarHBondContact OD1-CB 3.45Å; N264-N303 PolarHBondContact OD1-ND2 2.99Å
265L98.4Very high97.7Very high46 Ų4651.4 Ų51.424%0.24131%0.307CS..BIsolated β-bridgetrans-107.3155.5-179.6-62.3-178.9000111.5N259 N262 P299 L301N259-L265 HydrophobicContact CB-CB 4.01Å; N259-L265 WeakPolarHBondContact CB-O 3.38Å; N259-L265 PolarHBondContact N-O 2.62Å; N262-L265 HydrophobicContact CB-CB 4.41Å; N262-L265 HydrophobicContact CB-CD1 3.97Å; N262-L265 HydrophobicContact CB-CG 4.09Å; N262-L265 PolarHBondContact O-N 2.83Å; L265-P299 HydrophobicContact CD2-CB 4.12Å; L265-P299 HydrophobicContact CD2-CG 3.71Å; L265-L301 HydrophobicContact CD2-CD2 3.79Å
266I98.6Very high97.7Very high7 Ų756.9 Ų56.94%0.03633%0.33CS..BIsolated β-bridgetrans-74.7143170.6-51.8-57.1000110.2G257 F272 L300 R302G257-I266 CarbonylContact O-C 3.45Å; G257-I266 WeakPolarHBondContact O-CA 3.3Å; I266-F272 HydrophobicContact CG2-CB 4.48Å; I266-L300 HydrophobicContact CD1-CD2 4.42Å; I266-L300 HydrophobicContact CG1-CB 4.5Å; I266-L300 HydrophobicContact CG1-CD2 4.07Å; I266-R302 HydrophobicContact CD1-CB 3.68Å
267S98.5Very high97.7Very high14 Ų1457.2 Ų57.210%0.09833%0.333CS..  trans-54.4133.8174.91710000111.1D252 G257 A269 S270 S273D252-S267 WeakPolarHBondContact OD1-CB 3.43Å; D252-S267 PolarHBondContact OD1-OG 2.82Å; D252-S267 PolarHBondContact OD2-OG 2.82Å; G257-S267 WeakPolarHBondContact O-CB 3.11Å; G257-S267 PolarHBondContact O-N 2.99Å; S267-A269 PolarHBondContact O-N 2.85Å; S267-A269 PolarHBondContact OG-N 3.31Å; S267-S270 PolarHBondContact O-N 2.91Å; S267-S273 WeakPolarHBondContact O-CB 3.43Å
268P98Very high97.7Very high99 Ų9956.9 Ų56.964%0.64333%0.329SS*.THydrogen-bonded Turntrans-62.8-11.3179.2-22.835000115N259 S270 S273N259-P268 WeakPolarHBondContact ND2-CD 3.41Å; P268-S270 VanDerWaalsContact C-N 3.28Å; P268-S273 WeakPolarHBondContact CA-OG 3.27Å
269A97.6Very high97.7Very high77 Ų7750.3 Ų50.364%0.63630%0.304SS*.THydrogen-bonded Turntrans-79-11.7175.600000113D252 S267D252-A269 HydrophobicContact CB-CB 4.21Å; D252-A269 WeakPolarHBondContact OD2-CB 3.34Å; S267-A269 PolarHBondContact O-N 2.85Å; S267-A269 PolarHBondContact OG-N 3.31Å
270S98.3Very high97.6Very high6 Ų651 Ų514%0.04231%0.31CS..SBendtrans-96.9141.8174.9-177.20000111.6G256 S267 P268 F272 S273G256-S270 VanDerWaalsContact CA-CB 3.47Å; G256-S270 VanDerWaalsContact CA-OG 3.27Å; G256-S270 WeakPolarHBondContact CA-OG 3.14Å; S267-S270 PolarHBondContact O-N 2.91Å; P268-S270 VanDerWaalsContact C-N 3.28Å; S270-F272 PolarHBondContact O-N 3.13Å; S270-F272 VanDerWaalsContact O-N 3.15Å; S270-F272 WeakPolarHBondContact OG-CD2 3.27Å; S270-F272 PolarHBondContact OG-N 3.26Å; S270-S273 PolarHBondContact O-N 3.25Å; S270-S273 VanDerWaalsContact O-N 3.16Å; S270-S273 PolarHBondContact O-OG 2.92Å
271V97.6Very high97.6Very high59 Ų5948.7 Ų48.736%0.35829%0.286SS..G310 helixtrans-57.1-31.4175-59.80000112.4I136 N140 S273 S274I136-V271 HydrophobicContact CG2-CG2 3.7Å; N140-V271 HydrophobicContact CB-CG2 4.28Å; V271-S273 PolarHBondContact O-N 3.33Å; V271-S274 PolarHBondContact O-N 2.94Å; V271-S274 PolarHBondContact O-OG 3.44Å
272F98.6Very high97.5Very high0 Ų042.1 Ų42.10%025%0.253CS..G310 helixtrans-69.5-16.5-176.9-56.2-58.5000113.5I136 L139 L254 M255 I266 S270 S274 W275 P387I136-F272 HydrophobicContact CB-CZ 4.47Å; I136-F272 HydrophobicContact CG1-CE2 4.46Å; I136-F272 HydrophobicContact CG1-CZ 4.46Å; I136-F272 HydrophobicContact CG2-CE2 4Å; I136-F272 HydrophobicContact CG2-CZ 3.85Å; L139-F272 HydrophobicContact CB-CE1 4.35Å; L139-F272 HydrophobicContact CD1-CE1 4.42Å; L139-F272 HydrophobicContact CD1-CZ 4.29Å; L254-F272 WeakPolarHBondContact O-CE2 3.39Å; M255-F272 HydrophobicContact SD-CE2 4.19Å; M255-F272 HydrophobicContact SD-CZ 4.43Å; I266-F272 HydrophobicContact CG2-CB 4.48Å; S270-F272 PolarHBondContact O-N 3.13Å; S270-F272 VanDerWaalsContact O-N 3.15Å; S270-F272 WeakPolarHBondContact OG-CD2 3.27Å; S270-F272 PolarHBondContact OG-N 3.26Å; F272-S274 PolarHBondContact O-N 3.18Å; F272-W275 AromaticContact CD1-CD2 3.84Å; F272-W275 HydrophobicContact CD1-CD2 3.84Å; F272-W275 AromaticContact CD1-CE2 3.54Å; F272-W275 HydrophobicContact CD1-CE3 4.11Å; F272-W275 HydrophobicContact CD1-CG 4.5Å; F272-W275 AromaticContact CD1-CH2 3.89Å; F272-W275 HydrophobicContact CD1-CH2 3.89Å; F272-W275 AromaticContact CD1-CZ2 3.59Å; F272-W275 HydrophobicContact CD1-CZ2 3.59Å; F272-W275 HydrophobicContact CD1-CZ3 4.12Å; F272-W275 AromaticContact CE1-CE2 3.97Å; F272-W275 AromaticContact CE1-CH2 3.7Å; F272-W275 HydrophobicContact CE1-CH2 3.7Å; F272-W275 AromaticContact CE1-CZ2 3.51Å; F272-W275 HydrophobicContact CE1-CZ2 3.51Å; F272-W275 HydrophobicContact CE1-CZ3 4.3Å; F272-W275 WeakPolarHBondContact O-CB 3.16Å; F272-W275 PolarHBondContact O-N 3.38Å; F272-P387 HydrophobicContact CD1-CB 4.42Å; F272-P387 HydrophobicContact CD1-CG 3.74Å; F272-P387 HydrophobicContact CD2-CG 4.13Å; F272-P387 HydrophobicContact CE1-CB 3.95Å; F272-P387 HydrophobicContact CE1-CG 3.73Å; F272-P387 HydrophobicContact CE2-CG 4.12Å; F272-P387 HydrophobicContact CG-CG 3.96Å; F272-P387 HydrophobicContact CZ-CB 4.09Å; F272-P387 HydrophobicContact CZ-CG 3.92Å
273S98.2Very high97.5Very high40 Ų4043.8 Ų43.828%0.2826%0.259SS..G310 helixtrans-68.4-21.2175.7710000113.3S267 P268 S270 V271S267-S273 WeakPolarHBondContact O-CB 3.43Å; P268-S273 WeakPolarHBondContact CA-OG 3.27Å; S270-S273 PolarHBondContact O-N 3.25Å; S270-S273 VanDerWaalsContact O-N 3.16Å; S270-S273 PolarHBondContact O-OG 2.92Å; V271-S273 PolarHBondContact O-N 3.33Å
274S97.3Very high97.5Very high82 Ų8244.8 Ų44.857%0.57326%0.259SS*.G310 helixtrans-86.8-1317868.80000113.2V271 F272V271-S274 PolarHBondContact O-N 2.94Å; V271-S274 PolarHBondContact O-OG 3.44Å; F272-S274 PolarHBondContact O-N 3.18Å
275W98.3Very high97.4Very high9 Ų942 Ų423%0.03424%0.243CC..PPolyproline II helixtrans-67.3142.3-175.9-75.322.7000111.6L139 N140 K143 Y175 F272 L300L139-W275 HydrophobicContact CB-CH2 4.14Å; L139-W275 HydrophobicContact CB-CZ2 4.34Å; N140-W275 PolarHBondContact OD1-NE1 3.44Å; N140-W275 VanDerWaalsContact OD1-NE1 3.08Å; K143-W275 HydrophobicContact CB-CD2 4.42Å; K143-W275 HydrophobicContact CB-CH2 4.05Å; K143-W275 HydrophobicContact CB-CZ2 3.57Å; K143-W275 HydrophobicContact CD-CD2 4.21Å; K143-W275 HydrophobicContact CD-CE3 4.2Å; K143-W275 HydrophobicContact CD-CZ3 4.41Å; K143-W275 HydrophobicContact CG-CD2 3.8Å; K143-W275 HydrophobicContact CG-CE3 4.25Å; K143-W275 HydrophobicContact CG-CG 4.19Å; K143-W275 HydrophobicContact CG-CH2 4.34Å; K143-W275 HydrophobicContact CG-CZ2 3.91Å; Y175-W275 HydrophobicContact CD1-CH2 4.31Å; Y175-W275 AromaticContact CD1-CZ3 3.92Å; Y175-W275 HydrophobicContact CD1-CZ3 3.92Å; Y175-W275 AromaticContact CD2-CH2 3.58Å; Y175-W275 HydrophobicContact CD2-CH2 3.58Å; Y175-W275 AromaticContact CD2-CZ3 3.95Å; Y175-W275 HydrophobicContact CD2-CZ3 3.95Å; Y175-W275 HydrophobicContact CE1-CE3 4.49Å; Y175-W275 HydrophobicContact CE1-CH2 4.26Å; Y175-W275 AromaticContact CE1-CZ3 3.61Å; Y175-W275 HydrophobicContact CE1-CZ3 3.61Å; Y175-W275 AromaticContact CE2-CH2 3.51Å; Y175-W275 HydrophobicContact CE2-CH2 3.51Å; Y175-W275 AromaticContact CE2-CZ3 3.63Å; Y175-W275 HydrophobicContact CE2-CZ3 3.63Å; Y175-W275 HydrophobicContact CG-CH2 4.01Å; Y175-W275 HydrophobicContact CG-CZ3 4.11Å; Y175-W275 AromaticContact CZ-CH2 3.89Å; Y175-W275 AromaticContact CZ-CZ3 3.47Å; Y175-W275 VanDerWaalsContact CZ-CZ3 3.47Å; F272-W275 AromaticContact CD1-CD2 3.84Å; F272-W275 HydrophobicContact CD1-CD2 3.84Å; F272-W275 AromaticContact CD1-CE2 3.54Å; F272-W275 HydrophobicContact CD1-CE3 4.11Å; F272-W275 HydrophobicContact CD1-CG 4.5Å; F272-W275 AromaticContact CD1-CH2 3.89Å; F272-W275 HydrophobicContact CD1-CH2 3.89Å; F272-W275 AromaticContact CD1-CZ2 3.59Å; F272-W275 HydrophobicContact CD1-CZ2 3.59Å; F272-W275 HydrophobicContact CD1-CZ3 4.12Å; F272-W275 AromaticContact CE1-CE2 3.97Å; F272-W275 AromaticContact CE1-CH2 3.7Å; F272-W275 HydrophobicContact CE1-CH2 3.7Å; F272-W275 AromaticContact CE1-CZ2 3.51Å; F272-W275 HydrophobicContact CE1-CZ2 3.51Å; F272-W275 HydrophobicContact CE1-CZ3 4.3Å; F272-W275 WeakPolarHBondContact O-CB 3.16Å; F272-W275 PolarHBondContact O-N 3.38Å; W275-L300 PolarHBondContact O-N 3.17Å
276K98.1Very high97.3Very high115 Ų11539.9 Ų39.950%0.523%0.232SC..EExtended strand (participates in β ladder)trans-103.7136.9170.2-60.7-60.5-178.6-179.10110.2K143 G298K143-K276 WeakPolarHBondContact CE-O 3.48Å; K143-K276 PolarHBondContact NZ-O 3.25Å; K276-G298 CarbonylContact C-O 3.52Å; K276-G298 WeakPolarHBondContact CA-O 3.17Å; K276-G298 WeakPolarHBondContact CD-O 3.25Å
277V98.2Very high97.2Very high7 Ų743.6 Ų43.64%0.04225%0.252CS..EExtended strand (participates in β ladder)trans-82.9152.8175.2-55.20000110.5G296 E297 G298 L300 N385V277-G296 CarbonylContact O-C 3.54Å; V277-G296 WeakPolarHBondContact O-CA 3.43Å; V277-E297 HydrophobicContact CG2-CB 4.2Å; V277-E297 PolarHBondContact O-N 3.17Å; V277-G298 PolarHBondContact N-O 3.15Å; V277-L300 HydrophobicContact CG1-CB 4.37Å; V277-L300 HydrophobicContact CG1-CD1 4.01Å; V277-N385 WeakPolarHBondContact CA-OD1 3.48Å; V277-N385 HydrophobicContact CB-CB 4.12Å; V277-N385 HydrophobicContact CG1-CB 3.86Å
278I98.1Very high97.1Very high2 Ų250.1 Ų50.11%0.0127%0.274CS..  trans-126.9166.1168.165.1163.7000109.2I172 D176 V179 S280 N385I172-I278 HydrophobicContact CD1-CD1 4.09Å; D176-I278 HydrophobicContact CB-CD1 3.66Å; D176-I278 HydrophobicContact CB-CG1 4.42Å; V179-I278 HydrophobicContact CB-CD1 4.29Å; V179-I278 HydrophobicContact CB-CG1 4.17Å; V179-I278 HydrophobicContact CG1-CD1 4.23Å; V179-I278 HydrophobicContact CG1-CG1 3.67Å; I278-S280 PolarHBondContact O-N 2.89Å; I278-N385 PolarHBondContact N-OD1 3.21Å; I278-N385 PolarHBondContact O-ND2 2.98Å
279C97.3Very high96.9Very high0 Ų048 Ų480%026%0.256CS..SBendtrans57.833.4171.4-48.40000113.9Y183 Y285 C292 E297Y183-C279 HydrophobicContact CD1-CB 4.32Å; Y183-C279 HydrophobicContact CD2-CB 3.76Å; Y183-C279 HydrophobicContact CG-CB 3.6Å; C279-Y285 VanDerWaalsContact C-OH 3.23Å; C279-Y285 WeakPolarHBondContact CA-OH 3.37Å; C279-Y285 PolarHBondContact N-OH 2.89Å; C279-C292 WeakPolarHBondContact CA-SG 3.27Å; C279-C292 HydrophobicContact CB-CB 3.74Å; C279-C292 WeakPolarHBondContact CB-SG 3.4Å; C279-C292 PolarHBondContact N-SG 3.46Å; C279-C292 WeakPolarHBondContact SG-CB 3.3Å; C279-C292 CovalentContact SG-SG 2.03Å; C279-C292 PolarHBondContact SG-SG 3.08Å; C279-E297 PolarHBondContact N-OE2 3.33Å
280S95.6Very high96.8Very high35 Ų3546.2 Ų46.225%0.24524%0.237CC..  trans-1070.6-173.470.40000114I278 P282 Y285 E297 N379I278-S280 PolarHBondContact O-N 2.89Å; S280-P282 VanDerWaalsContact O-CD 3.29Å; S280-P282 WeakPolarHBondContact O-CD 3.29Å; S280-Y285 PolarHBondContact N-OH 3.27Å; S280-E297 WeakPolarHBondContact CA-OE2 3.28Å; S280-E297 WeakPolarHBondContact CB-OE2 3.27Å; S280-E297 PolarHBondContact N-OE2 2.03Å; S280-E297 PolarHBondContact OG-OE2 2.88Å; S280-N379 PolarHBondContact O-ND2 3.42Å
281Q95.6Very high96.7Very high69 Ų6946.1 Ų46.132%0.32224%0.236SC..  trans-121.860.9-172.8-60-179.7-3.400113.3E283 E284 Y285Q281-E283 VanDerWaalsContact C-N 3.29Å; Q281-E283 PolarHBondContact O-N 3.44Å; Q281-E283 VanDerWaalsContact O-N 3.17Å; Q281-E284 HydrophobicContact CB-CB 4.1Å; Q281-E284 PolarHBondContact O-N 3.07Å; Q281-E284 PolarHBondContact OE1-OE2 2.65Å; Q281-Y285 HydrophobicContact CB-CE1 4.26Å; Q281-Y285 HydrophobicContact CB-CE2 4.44Å; Q281-Y285 PolarHBondContact N-OH 2.96Å; Q281-Y285 VanDerWaalsContact N-OH 3.09Å; Q281-Y285 VanDerWaalsContact O-CD2 3.31Å; Q281-Y285 WeakPolarHBondContact O-CD2 3.36Å; Q281-Y285 WeakPolarHBondContact O-CE2 3.32Å; Q281-Y285 PolarHBondContact O-N 3.34Å
282P94.9Very high96.6Very high25 Ų2543.3 Ų43.316%0.16222%0.219CC..Hα-helixtrans-46.2-49.1-178.11.2-15.3000114.2S280 E284 Y285 N286S280-P282 VanDerWaalsContact O-CD 3.29Å; S280-P282 WeakPolarHBondContact O-CD 3.29Å; P282-E284 VanDerWaalsContact C-N 3.26Å; P282-E284 PolarHBondContact O-N 2.88Å; P282-Y285 PolarHBondContact O-N 3.06Å; P282-Y285 VanDerWaalsContact O-N 3.16Å; P282-N286 WeakPolarHBondContact O-CB 3.32Å; P282-N286 PolarHBondContact O-N 2.82Å; P282-N286 PolarHBondContact O-ND2 3.45Å; P282-N286 PolarHBondContact O-OD1 3.25Å
283E96.1Very high96.4Very high96 Ų9646.4 Ų46.445%0.44924%0.235SC..Hα-helixtrans-65.6-30.5-175.4-62.2-61.7163.900111.9R199 Q281 N287R199-E283 IonicContact NH2-OE1 3.63Å; R199-E283 IonicContact NH2-OE2 3.31Å; R199-E283 PolarHBondContact NH2-OE2 3.3Å; Q281-E283 VanDerWaalsContact C-N 3.29Å; Q281-E283 PolarHBondContact O-N 3.44Å; Q281-E283 VanDerWaalsContact O-N 3.17Å; E283-N287 VanDerWaalsContact O-CB 3.25Å; E283-N287 WeakPolarHBondContact O-CB 3.33Å; E283-N287 PolarHBondContact O-N 2.76Å; E283-N287 PolarHBondContact O-ND2 2.83Å
284E95.9Very high96.1Very high82 Ų8247 Ų4738%0.38324%0.238SC..Hα-helixtrans-69.3-45173.8-179.1170.3160.700111.1Q281 P282 N286 N287 R288Q281-E284 HydrophobicContact CB-CB 4.1Å; Q281-E284 PolarHBondContact O-N 3.07Å; Q281-E284 PolarHBondContact OE1-OE2 2.65Å; P282-E284 VanDerWaalsContact C-N 3.26Å; P282-E284 PolarHBondContact O-N 2.88Å; E284-N286 VanDerWaalsContact C-N 3.34Å; E284-N286 PolarHBondContact O-N 3.25Å; E284-N287 PolarHBondContact O-N 3.12Å; E284-R288 HydrophobicContact CG-CG 4.49Å; E284-R288 WeakPolarHBondContact O-CB 3.1Å; E284-R288 WeakPolarHBondContact O-CG 3.28Å; E284-R288 PolarHBondContact O-N 3.47Å; E284-R288 IonicContact OE1-CZ 2.75Å; E284-R288 IonicContact OE1-NH1 3.65Å; E284-R288 PolarHBondContact OE1-NH1 3.43Å
285Y96.1Very high96Very high11 Ų1147.3 Ų47.34%0.04324%0.236CC..Hα-helixtrans-61.4-44.7177.7-49.2-36000111.3Y183 C279 S280 Q281 P282 R288 E289 V290 C292 E297Y183-Y285 HydrophobicContact CD2-CE2 4.37Å; Y183-Y285 AromaticContact CE2-CD2 3.61Å; Y183-Y285 HydrophobicContact CE2-CD2 3.61Å; Y183-Y285 AromaticContact CE2-CE2 3.78Å; Y183-Y285 HydrophobicContact CE2-CE2 3.78Å; C279-Y285 VanDerWaalsContact C-OH 3.23Å; C279-Y285 WeakPolarHBondContact CA-OH 3.37Å; C279-Y285 PolarHBondContact N-OH 2.89Å; S280-Y285 PolarHBondContact N-OH 3.27Å; Q281-Y285 HydrophobicContact CB-CE1 4.26Å; Q281-Y285 HydrophobicContact CB-CE2 4.44Å; Q281-Y285 PolarHBondContact N-OH 2.96Å; Q281-Y285 VanDerWaalsContact N-OH 3.09Å; Q281-Y285 VanDerWaalsContact O-CD2 3.31Å; Q281-Y285 WeakPolarHBondContact O-CD2 3.36Å; Q281-Y285 WeakPolarHBondContact O-CE2 3.32Å; Q281-Y285 PolarHBondContact O-N 3.34Å; P282-Y285 PolarHBondContact O-N 3.06Å; P282-Y285 VanDerWaalsContact O-N 3.16Å; Y285-R288 CarbonylContact O-C 3.55Å; Y285-R288 PolarHBondContact O-N 2.91Å; Y285-E289 WeakPolarHBondContact O-CA 3.12Å; Y285-E289 PolarHBondContact O-N 2.88Å; Y285-V290 WeakPolarHBondContact CB-O 3.4Å; Y285-V290 PolarHBondContact O-N 2.75Å; Y285-V290 VanDerWaalsContact O-N 3.14Å; Y285-C292 HydrophobicContact CE2-CB 4.29Å; Y285-E297 PolarHBondContact OH-OE1 2.78Å; Y285-E297 PolarHBondContact OH-OE2 3.3Å
286N97.1Very high95.8Very high2 Ų249 Ų491%0.01126%0.256CS..Hα-helixtrans-62.2-43.9177.3-69.6-13.4000112D188 G195 V197 P282 E284 R288 E289D188-N286 PolarHBondContact OD2-ND2 3.43Å; G195-N286 WeakPolarHBondContact CA-O 3.14Å; G195-N286 PolarHBondContact N-O 3.25Å; V197-N286 HydrophobicContact CG1-CB 3.81Å; V197-N286 HydrophobicContact CG2-CB 4.48Å; P282-N286 WeakPolarHBondContact O-CB 3.32Å; P282-N286 PolarHBondContact O-N 2.82Å; P282-N286 PolarHBondContact O-ND2 3.45Å; P282-N286 PolarHBondContact O-OD1 3.25Å; E284-N286 VanDerWaalsContact C-N 3.34Å; E284-N286 PolarHBondContact O-N 3.25Å; N286-R288 VanDerWaalsContact C-N 3.26Å; N286-R288 PolarHBondContact O-N 3.2Å; N286-E289 PolarHBondContact O-N 3.29Å
287N97.1Very high95.8Very high85 Ų8545.7 Ų45.746%0.45524%0.242SC..Hα-helixtrans-67.3-28.2178.7-76.5-38000113P194 E283 E284P194-N287 WeakPolarHBondContact CA-O 3.39Å; P194-N287 VanDerWaalsContact CB-O 3.25Å; P194-N287 WeakPolarHBondContact CB-O 3.46Å; E283-N287 VanDerWaalsContact O-CB 3.25Å; E283-N287 WeakPolarHBondContact O-CB 3.33Å; E283-N287 PolarHBondContact O-N 2.76Å; E283-N287 PolarHBondContact O-ND2 2.83Å; E284-N287 PolarHBondContact O-N 3.12Å
288R95.5Very high95.7Very high151 Ų15146.3 Ų46.357%0.5725%0.25SS*.Hα-helixtrans-99.6-9.3-178.6-66.8172.961.9-171.2-6.2113.4E284 Y285 N286 V290E284-R288 HydrophobicContact CG-CG 4.49Å; E284-R288 WeakPolarHBondContact O-CB 3.1Å; E284-R288 WeakPolarHBondContact O-CG 3.28Å; E284-R288 PolarHBondContact O-N 3.47Å; E284-R288 IonicContact OE1-CZ 2.75Å; E284-R288 IonicContact OE1-NH1 3.65Å; E284-R288 PolarHBondContact OE1-NH1 3.43Å; Y285-R288 CarbonylContact O-C 3.55Å; Y285-R288 PolarHBondContact O-N 2.91Å; N286-R288 VanDerWaalsContact C-N 3.26Å; N286-R288 PolarHBondContact O-N 3.2Å; R288-V290 HydrophobicContact CB-CG1 4.15Å; R288-V290 HydrophobicContact CB-CG2 3.83Å; R288-V290 PolarHBondContact O-N 3.13Å
289E94.5Very high95.7Very high56 Ų5648.5 Ų48.526%0.26227%0.265SS..THydrogen-bonded Turntrans54.439.7-172.7-60.4174.8-110.600112.9F190 G192 G193 Y285 N286F190-E289 HydrophobicContact CD2-CB 4.28Å; F190-E289 VanDerWaalsContact CE2-C 3.48Å; G192-E289 VanDerWaalsContact CA-OE2 3.31Å; G192-E289 WeakPolarHBondContact CA-OE2 3.48Å; G193-E289 WeakPolarHBondContact CA-OE1 3.45Å; G193-E289 PolarHBondContact N-OE1 3.44Å; G193-E289 PolarHBondContact N-OE2 3.2Å; G193-E289 VanDerWaalsContact N-OE2 3.07Å; Y285-E289 WeakPolarHBondContact O-CA 3.12Å; Y285-E289 PolarHBondContact O-N 2.88Å; N286-E289 PolarHBondContact O-N 3.29Å
290V95Very high95.8Very high38 Ų3848.7 Ų48.723%0.2327%0.265CS..  trans-116.7156.2-179.6-61.30000111.1F190 Y285 R288F190-V290 WeakPolarHBondContact CZ-O 3.36Å; Y285-V290 WeakPolarHBondContact CB-O 3.4Å; Y285-V290 PolarHBondContact O-N 2.75Å; Y285-V290 VanDerWaalsContact O-N 3.14Å; R288-V290 HydrophobicContact CB-CG1 4.15Å; R288-V290 HydrophobicContact CB-CG2 3.83Å; R288-V290 PolarHBondContact O-N 3.13Å
291L96.3Very high95.9Very high5 Ų550.7 Ų50.73%0.02627%0.273CS..  trans-83.4153.2169.5-57.2-172.1000111.4A155 W180 Y184 F190 N293A155-L291 VanDerWaalsContact C-CD1 3.45Å; A155-L291 WeakPolarHBondContact O-CD1 3.28Å; W180-L291 HydrophobicContact CZ2-CD1 4.49Å; Y184-L291 HydrophobicContact CD2-CD1 4.41Å; Y184-L291 HydrophobicContact CE2-CD1 3.94Å; F190-L291 HydrophobicContact CE2-CD2 4.1Å; F190-L291 HydrophobicContact CZ-CD2 4.37Å; L291-N293 PolarHBondContact O-N 3.37Å
292C95.2Very high96Very high0 Ų047.7 Ų47.70%026%0.259CS..  trans-50.8138.8165.3174.80000111.1W180 Y183 C279 Y285W180-C292 PolarHBondContact NE1-O 3.27Å; W180-C292 VanDerWaalsContact NE1-O 3.16Å; Y183-C292 HydrophobicContact CD1-CB 3.66Å; Y183-C292 HydrophobicContact CD2-CB 4.22Å; Y183-C292 HydrophobicContact CE1-CB 3.37Å; Y183-C292 HydrophobicContact CE2-CB 3.97Å; Y183-C292 HydrophobicContact CG-CB 4.1Å; Y183-C292 PolarHBondContact OH-N 3.15Å; Y183-C292 VanDerWaalsContact OH-N 3.17Å; C279-C292 WeakPolarHBondContact CA-SG 3.27Å; C279-C292 HydrophobicContact CB-CB 3.74Å; C279-C292 WeakPolarHBondContact CB-SG 3.4Å; C279-C292 PolarHBondContact N-SG 3.46Å; C279-C292 WeakPolarHBondContact SG-CB 3.3Å; C279-C292 CovalentContact SG-SG 2.03Å; C279-C292 PolarHBondContact SG-SG 3.08Å; Y285-C292 HydrophobicContact CE2-CB 4.29Å
293N93.4Very high96.1Very high64 Ų6446.9 Ų46.934%0.34225%0.253SS..  trans-117.8-168.8174.169.333.7000110.9T154 L291 T295T154-N293 HydrophobicContact CG2-CB 4.05Å; L291-N293 PolarHBondContact O-N 3.37Å; N293-T295 VanDerWaalsContact C-N 3.33Å; N293-T295 PolarHBondContact O-N 3.06Å; N293-T295 WeakPolarHBondContact OD1-CB 3.49Å; N293-T295 PolarHBondContact OD1-N 2.75Å; N293-T295 PolarHBondContact OD1-OG1 3.1Å
294T92.8Very high96.2Very high54 Ų5443.4 Ų43.433%0.33124%0.239SC..SBendtrans-89.89.5-175.658.30000114.7I152 S170 D171 I172I152-T294 HydrophobicContact CD1-CG2 3.61Å; I152-T294 HydrophobicContact CG1-CG2 4.04Å; S170-T294 PolarHBondContact OG-OG1 3.45Å; D171-T294 WeakPolarHBondContact O-CG2 3.34Å; I172-T294 HydrophobicContact CB-CG2 4.01Å; I172-T294 HydrophobicContact CD1-CG2 3.93Å; I172-T294 HydrophobicContact CG1-CG2 3.8Å
295T94.3Very high96.2Very high88 Ų8840.8 Ų40.854%0.5423%0.234SC..  trans-74.5127.6178.8-50.30000109.9N293 E297N293-T295 VanDerWaalsContact C-N 3.33Å; N293-T295 PolarHBondContact O-N 3.06Å; N293-T295 WeakPolarHBondContact OD1-CB 3.49Å; N293-T295 PolarHBondContact OD1-N 2.75Å; N293-T295 PolarHBondContact OD1-OG1 3.1Å; T295-E297 PolarHBondContact O-N 3.04Å
296G95.9Very high96.2Very high44 Ų4445 Ų4545%0.45426%0.257SS..  trans-68.7129.217700000112.8V277V277-G296 CarbonylContact O-C 3.54Å; V277-G296 WeakPolarHBondContact O-CA 3.43Å
297E97Very high96.1Very high45 Ų4546 Ų4621%0.2126%0.262CS..  trans-102.1-4.3-171.4-72.4169.4-178.400114.2V277 C279 S280 Y285 T295V277-E297 HydrophobicContact CG2-CB 4.2Å; V277-E297 PolarHBondContact O-N 3.17Å; C279-E297 PolarHBondContact N-OE2 3.33Å; S280-E297 WeakPolarHBondContact CA-OE2 3.28Å; S280-E297 WeakPolarHBondContact CB-OE2 3.27Å; S280-E297 PolarHBondContact N-OE2 2.03Å; S280-E297 PolarHBondContact OG-OE2 2.88Å; Y285-E297 PolarHBondContact OH-OE1 2.78Å; Y285-E297 PolarHBondContact OH-OE2 3.3Å; T295-E297 PolarHBondContact O-N 3.04Å
298G97Very high96.1Very high20 Ų2046.2 Ų46.221%0.20626%0.263CS..EExtended strand (participates in β ladder)trans152.6177.2-177.400000112.3K276 V277K276-G298 CarbonylContact C-O 3.52Å; K276-G298 WeakPolarHBondContact CA-O 3.17Å; K276-G298 WeakPolarHBondContact CD-O 3.25Å; V277-G298 PolarHBondContact N-O 3.15Å
299P97.9Very high96Very high49 Ų4947.7 Ų47.732%0.31827%0.268SS..EExtended strand (participates in β ladder)trans-71162.2172.233.3-34.7000111.3L265 L301L265-P299 HydrophobicContact CD2-CB 4.12Å; L265-P299 HydrophobicContact CD2-CG 3.71Å; P299-L301 HydrophobicContact CG-CD2 4.14Å; P299-L301 PolarHBondContact O-N 3.29Å
300L97.6Very high96.1Very high3 Ų351.4 Ų51.42%0.01629%0.29CS..  trans-61.2131.1165.3-17171.4000110.3I266 W275 V277 N385 D386I266-L300 HydrophobicContact CD1-CD2 4.42Å; I266-L300 HydrophobicContact CG1-CB 4.5Å; I266-L300 HydrophobicContact CG1-CD2 4.07Å; W275-L300 PolarHBondContact O-N 3.17Å; V277-L300 HydrophobicContact CG1-CB 4.37Å; V277-L300 HydrophobicContact CG1-CD1 4.01Å; L300-N385 HydrophobicContact CD1-CB 4.23Å; L300-D386 HydrophobicContact CD1-CB 3.85Å; L300-D386 HydrophobicContact CD2-CB 4.49Å
301L98Very high96.1Very high78 Ų7855 Ų5541%0.40830%0.299SS..BIsolated β-bridgetrans-107.7133.5178.9-58.1-177.2000110.1N264 L265 P299 G375 S376N264-L301 WeakPolarHBondContact O-CA 3.36Å; L265-L301 HydrophobicContact CD2-CD2 3.79Å; P299-L301 HydrophobicContact CG-CD2 4.14Å; P299-L301 PolarHBondContact O-N 3.29Å; L301-G375 CarbonylContact O-C 3.35Å; L301-G375 WeakPolarHBondContact O-CA 3.36Å; L301-S376 PolarHBondContact N-OG 2.05Å; L301-S376 VanDerWaalsContact N-OG 3.08Å; L301-S376 PolarHBondContact O-N 3.47Å; L301-S376 PolarHBondContact O-OG 3.01Å
302R98.1Very high96.1Very high6 Ų654.7 Ų54.72%0.02330%0.298CS..  trans-155.6128.5176.4-156.3-170-69.4151.8-1111.3M255 G256 P263 N264 I266 P304 M373 D386M255-R302 PolarHBondContact O-NH1 2.9Å; M255-R302 PolarHBondContact O-NH2 3.5Å; G256-R302 PolarHBondContact O-NH1 3.4Å; P263-R302 VanDerWaalsContact O-O 3.12Å; N264-R302 CarbonylContact C-O 3.27Å; N264-R302 PolarHBondContact O-N 3.41Å; I266-R302 HydrophobicContact CD1-CB 3.68Å; R302-P304 HydrophobicContact CG-CG 3.79Å; R302-M373 HydrophobicContact CG-SD 4.45Å; R302-D386 IonicContact CZ-OD1 2.74Å; R302-D386 IonicContact CZ-OD2 3.69Å; R302-D386 IonicContact NE-OD1 2.66Å; R302-D386 IonicContact NE-OD2 2.68Å; R302-D386 PolarHBondContact NE-OD2 3.37Å; R302-D386 IonicContact NH2-OD1 2.75Å; R302-D386 PolarHBondContact NH2-OD1 3.26Å; R302-D386 IonicContact NH2-OD2 3.42Å; R302-D386 PolarHBondContact NH2-OD2 3.04Å; R302-D386 VanDerWaalsContact NH2-OD2 3.11Å
303N98Very high95.8Very high8 Ų858.8 Ų58.84%0.04332%0.324CS..  trans-142.969173.8-168.1-1.9000112.1R258 N264 G305 N306 M373 N374R258-N303 PolarHBondContact NH2-OD1 2.89Å; N264-N303 WeakPolarHBondContact OD1-CB 3.45Å; N264-N303 PolarHBondContact OD1-ND2 2.99Å; N303-G305 PolarHBondContact O-N 3.01Å; N303-N306 HydrophobicContact CB-CB 4.45Å; N303-N306 PolarHBondContact ND2-ND2 3.43Å; N303-N306 VanDerWaalsContact ND2-ND2 3.16Å; N303-N306 WeakPolarHBondContact O-CB 3.37Å; N303-N306 PolarHBondContact O-N 3.06Å; N303-M373 CarbonylContact C-O 3.55Å; N303-M373 PolarHBondContact N-O 3.21Å; N303-N374 PolarHBondContact N-O 2.03Å; N303-N374 VanDerWaalsContact N-O 3.11Å; N303-N374 WeakPolarHBondContact O-CB 3.18Å
304P97.3Very high95.7Very high22 Ų2260.5 Ų60.514%0.14333%0.326CS..THydrogen-bonded Turntrans-61.1135.3-169.1-21.134000112.4C247 R258 R302 N306 F372 M373C247-P304 HydrophobicContact CB-CB 3.8Å; C247-P304 HydrophobicContact CB-CG 3.94Å; R258-P304 PolarHBondContact NH2-O 3.42Å; R258-P304 VanDerWaalsContact NH2-O 3.12Å; R302-P304 HydrophobicContact CG-CG 3.79Å; P304-N306 VanDerWaalsContact C-N 3.31Å; P304-F372 CarbonylContact C-O 3.32Å; P304-F372 VanDerWaalsContact CA-O 3.28Å; P304-F372 WeakPolarHBondContact CA-O 3.43Å; P304-F372 HydrophobicContact CB-CD1 4.18Å; P304-F372 HydrophobicContact CB-CE1 3.6Å; P304-F372 HydrophobicContact CB-CZ 4.04Å; P304-M373 HydrophobicContact CB-SD 4.08Å; P304-M373 HydrophobicContact CG-SD 3.81Å
305G95.3Very high95.8Very high27 Ų2758.8 Ų58.828%0.27832%0.315SS..THydrogen-bonded Turntrans83.6-2.3-179.600000115.4N303 F372N303-G305 PolarHBondContact O-N 3.01Å; G305-F372 VanDerWaalsContact CA-CE2 3.44Å; G305-F372 PolarHBondContact N-O 3.34Å
306N96.6Very high96Very high101 Ų10154.7 Ų54.754%0.5429%0.29SS..  trans-100.528.1172.5-167.644.8000112.4N303 P304 N374N303-N306 HydrophobicContact CB-CB 4.45Å; N303-N306 PolarHBondContact ND2-ND2 3.43Å; N303-N306 VanDerWaalsContact ND2-ND2 3.16Å; N303-N306 WeakPolarHBondContact O-CB 3.37Å; N303-N306 PolarHBondContact O-N 3.06Å; P304-N306 VanDerWaalsContact C-N 3.31Å; N306-N374 PolarHBondContact O-ND2 3.22Å
307H95.9Very high96.1Very high23 Ų2354.3 Ų54.311%0.10628%0.279CS..SBendtrans-83.7170.6179.663.1-79.8000112.1R309 V312 V371 F372 N374H307-R309 PolarHBondContact O-N 3.37Å; H307-R309 VanDerWaalsContact O-N 3.11Å; H307-V312 PolarHBondContact CD2-O 3.45Å; H307-V312 PolarHBondContact NE2-O 3.15Å; H307-V371 HydrophobicContact CB-CG1 4.2Å; H307-V371 WeakPolarHBondContact CB-O 3.45Å; H307-F372 AromaticContact CE1-CD2 3.53Å; H307-F372 AromaticContact ND1-CD2 3.6Å; H307-N374 HydrophobicContact CB-CB 4.15Å
308D95.7Very high96.2Very high89 Ų8954.3 Ų54.348%0.47628%0.282SS..  trans-67.2107.9171.21806.9000110.9N310 R311 V312D308-N310 PolarHBondContact O-N 3.4Å; D308-N310 WeakPolarHBondContact OD1-CB 3.35Å; D308-N310 PolarHBondContact OD1-N 3.33Å; D308-N310 PolarHBondContact OD1-ND2 2.98Å; D308-R311 HydrophobicContact CB-CB 4.25Å; D308-R311 PolarHBondContact O-N 3.23Å; D308-R311 VanDerWaalsContact O-N 3.16Å; D308-V312 PolarHBondContact O-N 2.81Å
309R95Very high96.2Very high181 Ų18156.5 Ų56.568%0.68330%0.298SS*.THydrogen-bonded Turntrans-69.1-16.9-178.9-65.8-171.7178.8-162.7-1.4113.9H307 V312 P313H307-R309 PolarHBondContact O-N 3.37Å; H307-R309 VanDerWaalsContact O-N 3.11Å; R309-V312 WeakPolarHBondContact CA-O 3.3Å; R309-V312 CarbonylContact O-C 3.49Å; R309-P313 WeakPolarHBondContact O-CA 3.38Å
310N94.8Very high96.2Very high135 Ų13554.4 Ų54.472%0.72228%0.284SS*.THydrogen-bonded Turntrans-74.2-36.2172.8-61.1-44000110.8D308D308-N310 PolarHBondContact O-N 3.4Å; D308-N310 WeakPolarHBondContact OD1-CB 3.35Å; D308-N310 PolarHBondContact OD1-N 3.33Å; D308-N310 PolarHBondContact OD1-ND2 2.98Å
311R96Very high96.3Very high112 Ų11254.3 Ų54.342%0.42328%0.284SS..THydrogen-bonded Turntrans-76.2-41.7175.5-176.8171.7175.9179.10112D308 Q362 S363 V371D308-R311 HydrophobicContact CB-CB 4.25Å; D308-R311 PolarHBondContact O-N 3.23Å; D308-R311 VanDerWaalsContact O-N 3.16Å; R311-Q362 WeakPolarHBondContact O-CA 3.16Å; R311-S363 PolarHBondContact NE-OG 3.29Å; R311-S363 PolarHBondContact O-N 3Å; R311-V371 HydrophobicContact CG-CG1 4.43Å
312V96.6Very high96.3Very high0 Ų053.8 Ų53.80%028%0.281CS..  trans-127.397.7176.8179.50000110.4H307 D308 R309 V371H307-V312 PolarHBondContact CD2-O 3.45Å; H307-V312 PolarHBondContact NE2-O 3.15Å; D308-V312 PolarHBondContact O-N 2.81Å; R309-V312 WeakPolarHBondContact CA-O 3.3Å; R309-V312 CarbonylContact O-C 3.49Å; V312-V371 HydrophobicContact CB-CG1 4.45Å; V312-V371 HydrophobicContact CG2-CB 3.62Å; V312-V371 HydrophobicContact CG2-CG1 3.55Å; V312-V371 HydrophobicContact CG2-CG2 4.38Å
313P88.8Confident96.4Very high85 Ų8556.6 Ų56.655%0.55229%0.294SS*.SBendtrans-71.1-34.2-178.625.8-32.8000112.8R309R309-P313 WeakPolarHBondContact O-CA 3.38Å
314R91.2Very high96.4Very high101 Ų10156.2 Ų56.238%0.38129%0.292SS..SBendtrans-155.8158.1-178.659.6-179.4-176.576.5-4.1111.3D320 E354R314-D320 IonicContact CZ-OD1 3.84Å; R314-D320 IonicContact CZ-OD2 3.49Å; R314-D320 IonicContact NH1-OD1 3.63Å; R314-D320 IonicContact NH1-OD2 3.13Å; R314-D320 PolarHBondContact NH1-OD2 3.21Å; R314-D320 IonicContact NH2-OD1 2.97Å; R314-D320 PolarHBondContact NH2-OD1 2.64Å; R314-D320 IonicContact NH2-OD2 2.96Å; R314-D320 PolarHBondContact NH2-OD2 3.31Å; R314-E354 IonicContact CZ-OE1 2.85Å; R314-E354 IonicContact NH2-OE1 3.58Å; R314-E354 PolarHBondContact NH2-OE1 3.5Å
315L95.6Very high96.4Very high17 Ų1755.3 Ų55.39%0.08929%0.286CS..  trans-70.9158164.7-73.2177.3000110.6A244 L369 F372A244-L315 HydrophobicContact CB-CD1 4.22Å; A244-L315 WeakPolarHBondContact O-CB 3.36Å; A244-L315 WeakPolarHBondContact O-CD1 3.25Å; L315-L369 HydrophobicContact CD2-CD1 3.66Å; L315-F372 HydrophobicContact CD1-CD1 4.12Å; L315-F372 HydrophobicContact CD1-CD2 4.09Å; L315-F372 HydrophobicContact CD1-CE1 3.94Å; L315-F372 HydrophobicContact CD1-CE2 3.92Å; L315-F372 HydrophobicContact CD1-CG 4.2Å; L315-F372 HydrophobicContact CD1-CZ 3.86Å; L315-F372 HydrophobicContact CD2-CB 3.72Å; L315-F372 HydrophobicContact CD2-CD1 4Å; L315-F372 HydrophobicContact CD2-CD2 3.95Å; L315-F372 HydrophobicContact CD2-CG 3.62Å; L315-F372 HydrophobicContact CG-CD1 4.46Å; L315-F372 HydrophobicContact CG-CD2 3.93Å; L315-F372 HydrophobicContact CG-CE2 4.19Å; L315-F372 HydrophobicContact CG-CG 4.09Å
316P97.6Very high96.6Very high3 Ų356.4 Ų56.42%0.01930%0.297CS..  trans-81.4153.5-172.91.616.2000112.5W241 N243 D320 M365 S368W241-P316 HydrophobicContact CE3-CB 4.28Å; W241-P316 HydrophobicContact CE3-CG 3.88Å; W241-P316 HydrophobicContact CH2-CB 4.04Å; W241-P316 HydrophobicContact CH2-CG 3.72Å; W241-P316 HydrophobicContact CZ3-CB 3.45Å; W241-P316 VanDerWaalsContact CZ3-CB 3.45Å; W241-P316 HydrophobicContact CZ3-CG 3.3Å; N243-P316 PolarHBondContact N-O 3.46Å; P316-D320 WeakPolarHBondContact CA-OD2 3.34Å; P316-D320 HydrophobicContact CB-CB 4.27Å; P316-M365 HydrophobicContact CB-SD 3.67Å; P316-M365 HydrophobicContact CG-SD 4.29Å; P316-S368 WeakPolarHBondContact CD-OG 3.37Å; P316-S368 VanDerWaalsContact CG-OG 3.27Å; P316-S368 WeakPolarHBondContact CG-OG 3.45Å
317T98.3Very high96.7Very high35 Ų3551.9 Ų51.922%0.21527%0.273CS..  trans-107.2171.1-172.764.10000110.9N243 A319 D320 V321N243-T317 VanDerWaalsContact OD1-CA 3.25Å; N243-T317 WeakPolarHBondContact OD1-CA 2.97Å; N243-T317 VanDerWaalsContact OD1-CB 3.28Å; N243-T317 WeakPolarHBondContact OD1-CB 3.17Å; T317-A319 PolarHBondContact O-N 2.79Å; T317-A319 PolarHBondContact OG1-N 3.35Å; T317-D320 WeakPolarHBondContact CB-OD2 3.17Å; T317-D320 PolarHBondContact N-OD2 3.28Å; T317-D320 PolarHBondContact O-N 2.66Å; T317-D320 PolarHBondContact OG1-N 3.25Å; T317-D320 PolarHBondContact OG1-OD2 2.85Å; T317-V321 PolarHBondContact O-N 3.05Å
318T98.1Very high96.7Very high46 Ų4654.7 Ų54.728%0.28229%0.293SS..Hα-helixtrans-58.9-39.2170.6-59.60000111.8N243 D320 V321 D322N243-T318 PolarHBondContact ND2-OG1 2.73Å; N243-T318 PolarHBondContact OD1-N 3.4Å; T318-D320 VanDerWaalsContact C-N 3.34Å; T318-D320 PolarHBondContact O-N 3.32Å; T318-V321 PolarHBondContact O-N 3.32Å; T318-D322 VanDerWaalsContact O-CG 3.23Å; T318-D322 PolarHBondContact O-N 3.1Å
319A98.4Very high96.8Very high66 Ų6655.4 Ų55.455%0.54529%0.294SS..Hα-helixtrans-64.2-38.2179.600000112.4T317 D322 F323T317-A319 PolarHBondContact O-N 2.79Å; T317-A319 PolarHBondContact OG1-N 3.35Å; A319-D322 PolarHBondContact O-N 3.07Å; A319-F323 WeakPolarHBondContact O-CB 3.35Å; A319-F323 PolarHBondContact O-N 3.39Å
320D98.6Very high97Very high4 Ų446.9 Ų46.92%0.02126%0.261CS..Hα-helixtrans-63.6-42.4176.4-59-45.5000111.5R314 P316 T317 T318 F323 A324 P353 M365R314-D320 IonicContact CZ-OD1 3.84Å; R314-D320 IonicContact CZ-OD2 3.49Å; R314-D320 IonicContact NH1-OD1 3.63Å; R314-D320 IonicContact NH1-OD2 3.13Å; R314-D320 PolarHBondContact NH1-OD2 3.21Å; R314-D320 IonicContact NH2-OD1 2.97Å; R314-D320 PolarHBondContact NH2-OD1 2.64Å; R314-D320 IonicContact NH2-OD2 2.96Å; R314-D320 PolarHBondContact NH2-OD2 3.31Å; P316-D320 WeakPolarHBondContact CA-OD2 3.34Å; P316-D320 HydrophobicContact CB-CB 4.27Å; T317-D320 WeakPolarHBondContact CB-OD2 3.17Å; T317-D320 PolarHBondContact N-OD2 3.28Å; T317-D320 PolarHBondContact O-N 2.66Å; T317-D320 PolarHBondContact OG1-N 3.25Å; T317-D320 PolarHBondContact OG1-OD2 2.85Å; T318-D320 VanDerWaalsContact C-N 3.34Å; T318-D320 PolarHBondContact O-N 3.32Å; D320-F323 PolarHBondContact O-N 3.41Å; D320-A324 WeakPolarHBondContact O-CB 3.37Å; D320-A324 PolarHBondContact O-N 3.23Å; D320-P353 HydrophobicContact CB-CB 3.69Å; D320-P353 HydrophobicContact CB-CG 3.81Å; D320-M365 HydrophobicContact CB-CE 4.42Å; D320-M365 HydrophobicContact CB-SD 3.57Å; D320-M365 VanDerWaalsContact CB-SD 3.57Å
321V98.7Very high97.1Very high1 Ų141.4 Ų41.41%0.00623%0.231CC..Hα-helixtrans-65.2-42.5175.7175.20000110.8W241 R242 T317 T318 A324 V325 M365 I399W241-V321 HydrophobicContact CH2-CG2 4.34Å; W241-V321 HydrophobicContact CZ3-CG2 4.41Å; R242-V321 HydrophobicContact CG-CG2 3.89Å; T317-V321 PolarHBondContact O-N 3.05Å; T318-V321 PolarHBondContact O-N 3.32Å; V321-A324 PolarHBondContact O-N 3.32Å; V321-V325 HydrophobicContact CG1-CG2 4.27Å; V321-V325 WeakPolarHBondContact O-CB 3.29Å; V321-V325 VanDerWaalsContact O-CG2 3.26Å; V321-V325 WeakPolarHBondContact O-CG2 3.34Å; V321-V325 PolarHBondContact O-N 3.46Å; V321-M365 HydrophobicContact CB-CE 4.42Å; V321-M365 HydrophobicContact CG2-CE 3.79Å; V321-I399 HydrophobicContact CG1-CD1 4.01Å; V321-I399 HydrophobicContact CG1-CG1 3.99Å; V321-I399 HydrophobicContact CG1-CG2 4.03Å; V321-I399 HydrophobicContact CG2-CD1 3.98Å
322D98.5Very high97.2Very high67 Ų6737.5 Ų37.536%0.35822%0.22SC..Hα-helixtrans-65.2-39.8178.8-69.7-18.2000111.9T318 A319 G326 R402T318-D322 VanDerWaalsContact O-CG 3.23Å; T318-D322 PolarHBondContact O-N 3.1Å; A319-D322 PolarHBondContact O-N 3.07Å; D322-G326 PolarHBondContact O-N 3.36Å; D322-R402 IonicContact OD1-CZ 3.76Å; D322-R402 IonicContact OD1-NH1 3.82Å; D322-R402 PolarHBondContact OD1-NH1 3.28Å; D322-R402 IonicContact OD1-NH2 4Å; D322-R402 PolarHBondContact OD1-NH2 3.25Å
323F98.7Very high97Very high65 Ų6540.7 Ų40.729%0.28525%0.253SS..Hα-helixtrans-61.6-51.1173.1177.2-88.9000111.2A319 D320 V325 G326 L327 V346 P353 E354A319-F323 WeakPolarHBondContact O-CB 3.35Å; A319-F323 PolarHBondContact O-N 3.39Å; D320-F323 PolarHBondContact O-N 3.41Å; F323-V325 PolarHBondContact O-N 3.04Å; F323-G326 PolarHBondContact O-N 2.78Å; F323-L327 HydrophobicContact CE1-CD1 4.17Å; F323-L327 HydrophobicContact CE1-CD2 4.32Å; F323-L327 HydrophobicContact CE1-CG 4.41Å; F323-L327 HydrophobicContact CZ-CD2 4.35Å; F323-L327 PolarHBondContact O-N 3.18Å; F323-V346 HydrophobicContact CD1-CG1 4.44Å; F323-P353 WeakPolarHBondContact CB-O 3.01Å; F323-P353 WeakPolarHBondContact CD1-O 3.49Å; F323-P353 WeakPolarHBondContact CG-O 2.99Å; F323-E354 WeakPolarHBondContact CE2-O 3.26Å
324A98.6Very high97.1Very high0 Ų041.8 Ų41.80%025%0.254CS..Hα-helixtrans-56.7-50.7178.800000110.7D320 V321 G326 L327 F343 V346 M365D320-A324 WeakPolarHBondContact O-CB 3.37Å; D320-A324 PolarHBondContact O-N 3.23Å; V321-A324 PolarHBondContact O-N 3.32Å; A324-G326 PolarHBondContact O-N 2.8Å; A324-G326 VanDerWaalsContact O-N 3.17Å; A324-L327 WeakPolarHBondContact O-CB 3.5Å; A324-L327 PolarHBondContact O-N 3.45Å; A324-L327 VanDerWaalsContact O-N 3.08Å; A324-F343 VanDerWaalsContact O-CD2 3.25Å; A324-F343 WeakPolarHBondContact O-CD2 3.25Å; A324-V346 HydrophobicContact CB-CG1 3.76Å; A324-M365 HydrophobicContact CB-CE 4.23Å
325V98.6Very high97.3Very high4 Ų438.5 Ų38.52%0.02424%0.244CC..Hα-helixtrans-62.5-22178.3170.20000112.8V321 F323 I399 R402 H407V321-V325 HydrophobicContact CG1-CG2 4.27Å; V321-V325 WeakPolarHBondContact O-CB 3.29Å; V321-V325 VanDerWaalsContact O-CG2 3.26Å; V321-V325 WeakPolarHBondContact O-CG2 3.34Å; V321-V325 PolarHBondContact O-N 3.46Å; F323-V325 PolarHBondContact O-N 3.04Å; V325-I399 HydrophobicContact CG2-CG2 3.65Å; V325-R402 HydrophobicContact CG1-CG 4.03Å; V325-R402 HydrophobicContact CG2-CG 4.41Å; V325-H407 PolarHBondContact O-CE1 3.16Å
326G98.3Very high97.4Very high49 Ų4938.6 Ų38.651%0.50524%0.244SC..THydrogen-bonded Turntrans-81.8-7.9176.200000115.1D322 F323 A324D322-G326 PolarHBondContact O-N 3.36Å; F323-G326 PolarHBondContact O-N 2.78Å; A324-G326 PolarHBondContact O-N 2.8Å; A324-G326 VanDerWaalsContact O-N 3.17Å
327L98.4Very high97.3Very high7 Ų741.7 Ų41.74%0.03726%0.255CS..  trans-75.7122.9177.3-67169.2000110.3F323 A324 M341 F343 V346 W403 H407F323-L327 HydrophobicContact CE1-CD1 4.17Å; F323-L327 HydrophobicContact CE1-CD2 4.32Å; F323-L327 HydrophobicContact CE1-CG 4.41Å; F323-L327 HydrophobicContact CZ-CD2 4.35Å; F323-L327 PolarHBondContact O-N 3.18Å; A324-L327 WeakPolarHBondContact O-CB 3.5Å; A324-L327 PolarHBondContact O-N 3.45Å; A324-L327 VanDerWaalsContact O-N 3.08Å; L327-M341 HydrophobicContact CD2-CE 3.64Å; L327-M341 HydrophobicContact CD2-SD 4.46Å; L327-F343 HydrophobicContact CB-CB 4.19Å; L327-V346 HydrophobicContact CD1-CB 3.89Å; L327-V346 HydrophobicContact CD1-CG1 4.21Å; L327-V346 HydrophobicContact CD1-CG2 3.63Å; L327-W403 PolarHBondContact O-NE1 2.75Å; L327-H407 PolarHBondContact O-CE1 3.31Å
328P96.9Very high97.2Very high81 Ų8144.9 Ų44.953%0.52627%0.267SS..  trans-76.2-29.7-172.629.1-34.9000113.9W403 H407P328-W403 WeakPolarHBondContact O-CZ2 3.35Å; P328-H407 WeakPolarHBondContact CA-NE2 3.46Å
329E98.1Very high97.2Very high105 Ų10542.9 Ų42.949%0.49125%0.254SS..  trans-89.1126.4-176.1-59.5-54.714900110.6E331 T332 F343E329-E331 VanDerWaalsContact C-N 3.31Å; E329-E331 PolarHBondContact O-N 2.84Å; E329-T332 HydrophobicContact CB-CG2 3.73Å; E329-T332 HydrophobicContact CG-CG2 4.28Å; E329-F343 VanDerWaalsContact O-CB 3.26Å; E329-F343 WeakPolarHBondContact O-CB 3.17Å; E329-F343 PolarHBondContact O-N 3.11Å
330Y98.3Very high97.2Very high2 Ų243 Ų431%0.00825%0.246CC..SBendtrans-59.3-47.7174.5179.7-115.1000111A208 L211 P212 S342 F343 R344 F400 W403 Y414 F442A208-Y330 HydrophobicContact CB-CE1 4.1Å; A208-Y330 PolarHBondContact O-OH 3.29Å; L211-Y330 HydrophobicContact CD1-CE2 3.99Å; P212-Y330 WeakPolarHBondContact CD-OH 3.41Å; Y330-S342 PolarHBondContact O-OG 3.43Å; Y330-F343 AromaticContact CD2-CD1 3.99Å; Y330-F343 HydrophobicContact CD2-CD1 3.99Å; Y330-F343 HydrophobicContact CE2-CD1 4.34Å; Y330-F343 PolarHBondContact O-N 2.75Å; Y330-R344 HydrophobicContact CE2-CB 4.24Å; Y330-R344 WeakPolarHBondContact O-CB 3.28Å; Y330-R344 PolarHBondContact O-N 3.39Å; Y330-F400 HydrophobicContact CE2-CE2 4.09Å; Y330-W403 HydrophobicContact CD2-CH2 4.02Å; Y330-W403 AromaticContact CD2-CZ3 3.99Å; Y330-W403 HydrophobicContact CD2-CZ3 3.99Å; Y330-W403 HydrophobicContact CG-CH2 4.3Å; Y330-Y414 HydrophobicContact CD1-CD2 4.17Å; Y330-Y414 AromaticContact CE1-CD2 3.6Å; Y330-Y414 HydrophobicContact CE1-CD2 3.6Å; Y330-Y414 AromaticContact CE1-CE2 3.63Å; Y330-Y414 HydrophobicContact CE1-CE2 3.63Å; Y330-F442 AromaticContact CD1-CE2 3.99Å; Y330-F442 HydrophobicContact CD1-CE2 3.99Å; Y330-F442 HydrophobicContact CD1-CZ 4.26Å; Y330-F442 HydrophobicContact CD2-CD2 4.47Å; Y330-F442 AromaticContact CD2-CE2 3.37Å; Y330-F442 HydrophobicContact CD2-CE2 3.37Å; Y330-F442 AromaticContact CD2-CZ 3.82Å; Y330-F442 HydrophobicContact CD2-CZ 3.82Å; Y330-F442 HydrophobicContact CE1-CD2 4.45Å; Y330-F442 HydrophobicContact CE1-CE2 4.05Å; Y330-F442 HydrophobicContact CE2-CD2 4.17Å; Y330-F442 AromaticContact CE2-CE2 3.42Å; Y330-F442 HydrophobicContact CE2-CE2 3.42Å; Y330-F442 VanDerWaalsContact CE2-CE2 3.42Å; Y330-F442 HydrophobicContact CE2-CZ 4.32Å; Y330-F442 AromaticContact CG-CE2 3.66Å; Y330-F442 HydrophobicContact CG-CE2 3.66Å; Y330-F442 AromaticContact CG-CZ 3.78Å; Y330-F442 HydrophobicContact CG-CZ 3.78Å; Y330-F442 AromaticContact CZ-CE2 3.78Å
331E97.3Very high97.2Very high19 Ų1946.7 Ų46.79%0.08926%0.264CS..  trans-141.9156.5-177.5-88.6-72.7-151.400111.4A208 E329 M335 S342 R344A208-E331 WeakPolarHBondContact CA-OE1 3.22Å; A208-E331 HydrophobicContact CB-CG 3.98Å; A208-E331 PolarHBondContact N-OE1 3.17Å; A208-E331 VanDerWaalsContact N-OE1 3.16Å; E329-E331 VanDerWaalsContact C-N 3.31Å; E329-E331 PolarHBondContact O-N 2.84Å; E331-M335 HydrophobicContact CB-CG 4.25Å; E331-S342 WeakPolarHBondContact OE2-CB 3.36Å; E331-S342 PolarHBondContact OE2-OG 3.39Å; E331-R344 VanDerWaalsContact CD-NH2 3.32Å; E331-R344 HydrophobicContact CG-CB 4.24Å; E331-R344 IonicContact OE1-CZ 2.65Å; E331-R344 IonicContact OE1-NE 3.65Å; E331-R344 PolarHBondContact OE1-NE 2.56Å; E331-R344 IonicContact OE1-NH2 3.69Å; E331-R344 PolarHBondContact OE1-NH2 2.85Å; E331-R344 IonicContact OE2-CZ 3.53Å; E331-R344 IonicContact OE2-NE 2.75Å; E331-R344 IonicContact OE2-NH2 3.62Å; E331-R344 PolarHBondContact OE2-NH2 3.23Å; E331-R344 VanDerWaalsContact OE2-NH2 3.13Å
332T97.1Very high97.2Very high30 Ų3046.6 Ų46.618%0.18426%0.264CS..  trans-146.9165.1-178.464.30000111.6E329 N334 M335 A339 N340 S342E329-T332 HydrophobicContact CB-CG2 3.73Å; E329-T332 HydrophobicContact CG-CG2 4.28Å; T332-N334 PolarHBondContact O-N 3.1Å; T332-M335 PolarHBondContact O-N 3.35Å; T332-A339 WeakPolarHBondContact O-CB 3.37Å; T332-N340 WeakPolarHBondContact CB-O 3.32Å; T332-N340 PolarHBondContact OG1-O 2.69Å; T332-S342 WeakPolarHBondContact OG1-CB 3.28Å
333G93.7Very high97.2Very high67 Ų6743.4 Ų43.469%0.69125%0.247SC*.THydrogen-bonded Turntrans55.3-128169.700000113.1M335G333-M335 PolarHBondContact O-N 2.94Å
334N90.1Very high97.2Very high109 Ų10940.3 Ų40.358%0.58323%0.233SC*.THydrogen-bonded Turntrans-76.4-3.6-179.6-64.3-10.3000113.6T332 D336T332-N334 PolarHBondContact O-N 3.1Å; N334-D336 WeakPolarHBondContact CB-OD2 3.23Å; N334-D336 PolarHBondContact O-N 3.34Å
335M96.3Very high97.2Very high32 Ų3240.3 Ų40.316%0.15823%0.233CC..SBendtrans57.135.9179.9-53.5169.3-82.200112.4S207 E331 T332 G333 P415 N418 A419 P420S207-M335 WeakPolarHBondContact CB-O 3.03Å; S207-M335 PolarHBondContact OG-O 3.27Å; E331-M335 HydrophobicContact CB-CG 4.25Å; T332-M335 PolarHBondContact O-N 3.35Å; G333-M335 PolarHBondContact O-N 2.94Å; M335-P415 HydrophobicContact SD-CB 3.4Å; M335-P415 WeakPolarHBondContact SD-CB 3.41Å; M335-P415 HydrophobicContact SD-CG 4.03Å; M335-N418 HydrophobicContact CE-CB 4.32Å; M335-A419 HydrophobicContact SD-CB 4.42Å; M335-P420 WeakPolarHBondContact O-CD 3.05Å
336D96.3Very high97.2Very high18 Ų1840.1 Ų40.110%0.09623%0.232CC..SBendtrans-125.2-172.1-179.964.222.2000111.3E206 N334 F338 A339 R344 P420E206-D336 CarbonylContact O-C 3.36Å; E206-D336 WeakPolarHBondContact O-CA 3.31Å; N334-D336 WeakPolarHBondContact CB-OD2 3.23Å; N334-D336 PolarHBondContact O-N 3.34Å; D336-F338 PolarHBondContact O-N 3.44Å; D336-F338 WeakPolarHBondContact OD1-CA 3.38Å; D336-F338 WeakPolarHBondContact OD1-CB 3.28Å; D336-F338 PolarHBondContact OD1-N 3.01Å; D336-A339 VanDerWaalsContact O-CB 3.27Å; D336-A339 WeakPolarHBondContact O-CB 3.35Å; D336-A339 PolarHBondContact O-N 2.63Å; D336-R344 PolarHBondContact O-NH2 3.21Å; D336-P420 HydrophobicContact CB-CG 4.25Å
337R96.2Very high97.2Very high68 Ų6837.8 Ų37.826%0.25721%0.208SC..THydrogen-bonded Turntrans-59.7-1317759.9174.7176-123.8-8.9114.6D200 E206 N345 F350D200-R337 IonicContact OD1-CZ 3.31Å; D200-R337 IonicContact OD1-NH1 3.95Å; D200-R337 PolarHBondContact OD1-NH1 2.85Å; D200-R337 IonicContact OD1-NH2 3.36Å; D200-R337 PolarHBondContact OD1-NH2 3.33Å; D200-R337 IonicContact OD2-NH2 2.71Å; E206-R337 HydrophobicContact CB-CB 4.25Å; E206-R337 PolarHBondContact O-N 3.08Å; E206-R337 IonicContact OE1-NH1 3.33Å; E206-R337 PolarHBondContact OE1-NH1 2.91Å; E206-R337 VanDerWaalsContact OE2-CD 3.29Å; E206-R337 WeakPolarHBondContact OE2-CD 3.24Å; E206-R337 IonicContact OE2-CZ 2.78Å; E206-R337 IonicContact OE2-NE 3.45Å; E206-R337 IonicContact OE2-NH1 3.83Å; E206-R337 PolarHBondContact OE2-NH1 3.47Å; R337-N345 WeakPolarHBondContact CA-OD1 3.03Å; R337-N345 PolarHBondContact O-ND2 3.17Å; R337-F350 HydrophobicContact CB-CB 4.14Å; R337-F350 HydrophobicContact CB-CD1 3.87Å; R337-F350 HydrophobicContact CB-CD2 3.87Å; R337-F350 HydrophobicContact CB-CE1 4.17Å; R337-F350 HydrophobicContact CB-CE2 4.18Å; R337-F350 HydrophobicContact CB-CG 3.7Å; R337-F350 HydrophobicContact CB-CZ 4.32Å; R337-F350 WeakPolarHBondContact O-CB 3.1Å
338F96.8Very high97.2Very high103 Ų10337.5 Ų37.545%0.45221%0.206SC..THydrogen-bonded Turntrans-98.42.6177.7-53.1-71.9000113.4D336 N340D336-F338 PolarHBondContact O-N 3.44Å; D336-F338 WeakPolarHBondContact OD1-CA 3.38Å; D336-F338 WeakPolarHBondContact OD1-CB 3.28Å; D336-F338 PolarHBondContact OD1-N 3.01Å; F338-N340 PolarHBondContact O-N 2.8Å
339A97.4Very high97.3Very high3 Ų333.7 Ų33.73%0.02518%0.181CC..  trans-63.6125.417900000112.2T332 D336 N345T332-A339 WeakPolarHBondContact O-CB 3.37Å; D336-A339 VanDerWaalsContact O-CB 3.27Å; D336-A339 WeakPolarHBondContact O-CB 3.35Å; D336-A339 PolarHBondContact O-N 2.63Å; A339-N345 HydrophobicContact CB-CB 4.21Å; A339-N345 PolarHBondContact N-ND2 3.41Å; A339-N345 PolarHBondContact O-ND2 3.12Å
340N98.3Very high97.3Very high68 Ų6830.6 Ų30.636%0.36417%0.166SC..SBendtrans-94.8143.3177.2-66.6-34.6000110.8T332 F338 S342 G356 Q357 A358T332-N340 WeakPolarHBondContact CB-O 3.32Å; T332-N340 PolarHBondContact OG1-O 2.69Å; F338-N340 PolarHBondContact O-N 2.8Å; N340-S342 PolarHBondContact O-N 2.95Å; N340-G356 CarbonylContact C-O 3.48Å; N340-G356 WeakPolarHBondContact CA-O 3.42Å; N340-Q357 PolarHBondContact ND2-OE1 2.76Å; N340-Q357 WeakPolarHBondContact OD1-CA 3.37Å; N340-Q357 PolarHBondContact OD1-OE1 2.59Å; N340-A358 PolarHBondContact OD1-N 3.2Å
341M98Very high97.3Very high82 Ų8230.5 Ų30.540%0.40417%0.166SC..SBendtrans58.422.5-179-51.9-61.7-67.700113.3L327 T355 G356L327-M341 HydrophobicContact CD2-CE 3.64Å; L327-M341 HydrophobicContact CD2-SD 4.46Å; M341-T355 VanDerWaalsContact SD-O 3.4Å; M341-G356 PolarHBondContact N-O 3.34Å
342S98.6Very high97.3Very high0 Ų030.4 Ų30.40%017%0.167CC..  trans-88.9122.2173.1161.90000109.3Y330 E331 T332 N340 R344 N345 V346Y330-S342 PolarHBondContact O-OG 3.43Å; E331-S342 WeakPolarHBondContact OE2-CB 3.36Å; E331-S342 PolarHBondContact OE2-OG 3.39Å; T332-S342 WeakPolarHBondContact OG1-CB 3.28Å; N340-S342 PolarHBondContact O-N 2.95Å; S342-R344 VanDerWaalsContact C-N 3.3Å; S342-R344 PolarHBondContact O-N 3.29Å; S342-R344 PolarHBondContact OG-N 3.1Å; S342-N345 PolarHBondContact O-N 3.38Å; S342-N345 PolarHBondContact OG-N 3.29Å; S342-N345 VanDerWaalsContact OG-N 3.09Å; S342-V346 WeakPolarHBondContact O-CB 3.34Å; S342-V346 WeakPolarHBondContact O-CG2 3.43Å; S342-V346 PolarHBondContact O-N 2.92Å
343F98.8Very high97.3Very high0 Ų029.3 Ų29.30%016%0.161CC..Hα-helixtrans-55.2-47.5173.5163.4-110.2000111.1L211 A324 L327 E329 Y330 N345 V346 L347 F400 W403L211-F343 HydrophobicContact CD1-CD1 4.24Å; L211-F343 HydrophobicContact CD1-CE1 3.53Å; L211-F343 HydrophobicContact CD1-CZ 4.22Å; A324-F343 VanDerWaalsContact O-CD2 3.25Å; A324-F343 WeakPolarHBondContact O-CD2 3.25Å; L327-F343 HydrophobicContact CB-CB 4.19Å; E329-F343 VanDerWaalsContact O-CB 3.26Å; E329-F343 WeakPolarHBondContact O-CB 3.17Å; E329-F343 PolarHBondContact O-N 3.11Å; Y330-F343 AromaticContact CD2-CD1 3.99Å; Y330-F343 HydrophobicContact CD2-CD1 3.99Å; Y330-F343 HydrophobicContact CE2-CD1 4.34Å; Y330-F343 PolarHBondContact O-N 2.75Å; F343-N345 PolarHBondContact O-N 2.98Å; F343-V346 PolarHBondContact O-N 3.11Å; F343-L347 HydrophobicContact CE1-CD2 4.24Å; F343-L347 HydrophobicContact CE2-CB 4.22Å; F343-L347 HydrophobicContact CE2-CD2 3.91Å; F343-L347 HydrophobicContact CZ-CB 4.45Å; F343-L347 HydrophobicContact CZ-CD2 3.49Å; F343-L347 VanDerWaalsContact CZ-CD2 3.49Å; F343-L347 WeakPolarHBondContact O-CB 3.5Å; F343-L347 PolarHBondContact O-N 3.12Å; F343-F400 AromaticContact CE1-CD2 3.91Å; F343-F400 HydrophobicContact CE1-CD2 3.91Å; F343-W403 HydrophobicContact CD1-CB 4.36Å; F343-W403 AromaticContact CD1-CD1 3.76Å; F343-W403 AromaticContact CD1-CD2 3.55Å; F343-W403 HydrophobicContact CD1-CD2 3.55Å; F343-W403 AromaticContact CD1-CE2 3.7Å; F343-W403 HydrophobicContact CD1-CE3 4.08Å; F343-W403 AromaticContact CD1-CG 3.65Å; F343-W403 HydrophobicContact CD1-CG 3.65Å; F343-W403 HydrophobicContact CD1-CZ2 4.4Å; F343-W403 AromaticContact CD1-NE1 3.75Å; F343-W403 HydrophobicContact CD2-CB 4.31Å; F343-W403 AromaticContact CD2-CD1 3.32Å; F343-W403 HydrophobicContact CD2-CD2 4.49Å; F343-W403 AromaticContact CD2-CG 3.81Å; F343-W403 HydrophobicContact CD2-CG 3.81Å; F343-W403 AromaticContact CD2-NE1 3.78Å; F343-W403 HydrophobicContact CE1-CB 3.72Å; F343-W403 AromaticContact CE1-CD1 3.99Å; F343-W403 AromaticContact CE1-CD2 3.65Å; F343-W403 HydrophobicContact CE1-CD2 3.65Å; F343-W403 AromaticContact CE1-CE3 3.99Å; F343-W403 HydrophobicContact CE1-CE3 3.99Å; F343-W403 AromaticContact CE1-CG 3.5Å; F343-W403 HydrophobicContact CE1-CG 3.5Å; F343-W403 HydrophobicContact CE2-CB 3.66Å; F343-W403 AromaticContact CE2-CD1 3.57Å; F343-W403 AromaticContact CE2-CG 3.66Å; F343-W403 HydrophobicContact CE2-CG 3.66Å; F343-W403 AromaticContact CG-CD1 3.4Å; F343-W403 VanDerWaalsContact CG-CD1 3.4Å; F343-W403 AromaticContact CG-CD2 3.99Å; F343-W403 HydrophobicContact CG-CD2 3.99Å; F343-W403 AromaticContact CG-CE2 3.82Å; F343-W403 AromaticContact CG-CG 3.79Å; F343-W403 HydrophobicContact CG-CG 3.79Å; F343-W403 AromaticContact CG-NE1 3.39Å; F343-W403 HydrophobicContact CZ-CB 3.31Å; F343-W403 AromaticContact CZ-CD1 3.89Å; F343-W403 HydrophobicContact CZ-CD2 4.16Å; F343-W403 AromaticContact CZ-CG 3.5Å; F343-W403 HydrophobicContact CZ-CG 3.5Å; F343-W403 VanDerWaalsContact CZ-CG 3.5Å
344R98.7Very high97.5Very high0 Ų032 Ų320%016%0.155CC..Hα-helixtrans-56.3-50.9178.5-175.7-77.3-55.7161.55.9110.4E206 S207 F210 Y330 E331 D336 S342 V346 L347 E348E206-R344 VanDerWaalsContact C-NH1 3.25Å; E206-R344 PolarHBondContact O-NH1 2.73Å; S207-R344 WeakPolarHBondContact O-CD 3.26Å; F210-R344 HydrophobicContact CB-CG 4.26Å; F210-R344 HydrophobicContact CD1-CG 4.42Å; Y330-R344 HydrophobicContact CE2-CB 4.24Å; Y330-R344 WeakPolarHBondContact O-CB 3.28Å; Y330-R344 PolarHBondContact O-N 3.39Å; E331-R344 VanDerWaalsContact CD-NH2 3.32Å; E331-R344 HydrophobicContact CG-CB 4.24Å; E331-R344 IonicContact OE1-CZ 2.65Å; E331-R344 IonicContact OE1-NE 3.65Å; E331-R344 PolarHBondContact OE1-NE 2.56Å; E331-R344 IonicContact OE1-NH2 3.69Å; E331-R344 PolarHBondContact OE1-NH2 2.85Å; E331-R344 IonicContact OE2-CZ 3.53Å; E331-R344 IonicContact OE2-NE 2.75Å; E331-R344 IonicContact OE2-NH2 3.62Å; E331-R344 PolarHBondContact OE2-NH2 3.23Å; E331-R344 VanDerWaalsContact OE2-NH2 3.13Å; D336-R344 PolarHBondContact O-NH2 3.21Å; S342-R344 VanDerWaalsContact C-N 3.3Å; S342-R344 PolarHBondContact O-N 3.29Å; S342-R344 PolarHBondContact OG-N 3.1Å; R344-V346 PolarHBondContact O-N 2.91Å; R344-L347 PolarHBondContact O-N 3.26Å; R344-E348 VanDerWaalsContact CD-OE2 3.28Å; R344-E348 WeakPolarHBondContact CD-OE2 3.01Å; R344-E348 IonicContact CZ-OE2 3.6Å; R344-E348 IonicContact NE-OE2 4Å; R344-E348 IonicContact NH1-OE2 2.81Å; R344-E348 PolarHBondContact NH1-OE2 2.74Å; R344-E348 WeakPolarHBondContact O-CB 3.05Å; R344-E348 PolarHBondContact O-N 3.11Å
345N98.6Very high97.8Very high0 Ų030.4 Ų30.40%015%0.15CC..Hα-helixtrans-70.3-33.8-174-158.639.1000113.5R337 A339 S342 F343 G349 F350 A351R337-N345 WeakPolarHBondContact CA-OD1 3.03Å; R337-N345 PolarHBondContact O-ND2 3.17Å; A339-N345 HydrophobicContact CB-CB 4.21Å; A339-N345 PolarHBondContact N-ND2 3.41Å; A339-N345 PolarHBondContact O-ND2 3.12Å; S342-N345 PolarHBondContact O-N 3.38Å; S342-N345 PolarHBondContact OG-N 3.29Å; S342-N345 VanDerWaalsContact OG-N 3.09Å; F343-N345 PolarHBondContact O-N 2.98Å; N345-G349 PolarHBondContact O-N 3.22Å; N345-F350 PolarHBondContact O-N 3.03Å; N345-F350 VanDerWaalsContact O-N 3.16Å; N345-F350 WeakPolarHBondContact OD1-CB 2.81Å; N345-A351 PolarHBondContact O-N 3.11Å
346V98.8Very high97.9Very high0 Ų028.9 Ų28.90%014%0.142CC..Hα-helixtrans-68.5-45.8173.1171.90000110.7F323 A324 L327 S342 F343 R344 G349 A351 P353 M365F323-V346 HydrophobicContact CD1-CG1 4.44Å; A324-V346 HydrophobicContact CB-CG1 3.76Å; L327-V346 HydrophobicContact CD1-CB 3.89Å; L327-V346 HydrophobicContact CD1-CG1 4.21Å; L327-V346 HydrophobicContact CD1-CG2 3.63Å; S342-V346 WeakPolarHBondContact O-CB 3.34Å; S342-V346 WeakPolarHBondContact O-CG2 3.43Å; S342-V346 PolarHBondContact O-N 2.92Å; F343-V346 PolarHBondContact O-N 3.11Å; R344-V346 PolarHBondContact O-N 2.91Å; V346-G349 PolarHBondContact O-N 3.3Å; V346-A351 HydrophobicContact CB-CB 4.45Å; V346-A351 HydrophobicContact CG2-CB 3.58Å; V346-P353 HydrophobicContact CG1-CB 4.02Å; V346-M365 WeakPolarHBondContact O-CB 3.5Å; V346-M365 WeakPolarHBondContact O-CG 3.44Å
347L98.9Very high98Very high0 Ų032 Ų320%016%0.156CC..Hα-helixtrans-67.3-41.2179.5-18056.3000112.3L211 F343 R344 G349 M365 H366 I396 I399L211-L347 HydrophobicContact CD1-CD2 4.05Å; L211-L347 HydrophobicContact CD2-CD2 3.8Å; L211-L347 HydrophobicContact CD2-CG 4.47Å; F343-L347 HydrophobicContact CE1-CD2 4.24Å; F343-L347 HydrophobicContact CE2-CB 4.22Å; F343-L347 HydrophobicContact CE2-CD2 3.91Å; F343-L347 HydrophobicContact CZ-CB 4.45Å; F343-L347 HydrophobicContact CZ-CD2 3.49Å; F343-L347 VanDerWaalsContact CZ-CD2 3.49Å; F343-L347 WeakPolarHBondContact O-CB 3.5Å; F343-L347 PolarHBondContact O-N 3.12Å; R344-L347 PolarHBondContact O-N 3.26Å; L347-G349 VanDerWaalsContact C-N 3.26Å; L347-G349 PolarHBondContact O-N 3.49Å; L347-M365 HydrophobicContact CD1-CE 4.08Å; L347-M365 WeakPolarHBondContact O-CB 3.46Å; L347-H366 VanDerWaalsContact O-CB 3.3Å; L347-H366 WeakPolarHBondContact O-CB 3.28Å; L347-H366 PolarHBondContact O-N 2.83Å; L347-H366 VanDerWaalsContact O-N 3.15Å; L347-I396 HydrophobicContact CD1-CD1 4.04Å; L347-I396 HydrophobicContact CD2-CG2 4.3Å; L347-I396 HydrophobicContact CG-CG2 4.37Å; L347-I399 HydrophobicContact CD1-CB 4.16Å; L347-I399 HydrophobicContact CD1-CD1 3.96Å; L347-I399 HydrophobicContact CD1-CG2 3.77Å; L347-I399 HydrophobicContact CD2-CB 4.17Å; L347-I399 HydrophobicContact CD2-CG2 3.89Å
348E98.8Very high98Very high1 Ų129.9 Ų29.91%0.00515%0.153CC..Hα-helixtrans-62.3-37.2174.6-173.9168.1-163.800111.5H205 E206 F210 R344 F350 H366 N367H205-E348 WeakPolarHBondContact CA-OE1 3.47Å; H205-E348 WeakPolarHBondContact CB-OE1 3.32Å; E206-E348 PolarHBondContact N-OE1 3.44Å; E206-E348 PolarHBondContact N-OE2 2.78Å; F210-E348 HydrophobicContact CD1-CB 3.76Å; F210-E348 HydrophobicContact CD1-CG 3.98Å; F210-E348 HydrophobicContact CD2-CG 4.19Å; F210-E348 HydrophobicContact CE1-CB 3.7Å; F210-E348 HydrophobicContact CE1-CG 3.95Å; F210-E348 HydrophobicContact CE2-CG 4.15Å; F210-E348 HydrophobicContact CG-CB 4.37Å; F210-E348 HydrophobicContact CG-CG 4.13Å; F210-E348 HydrophobicContact CZ-CB 4.25Å; F210-E348 HydrophobicContact CZ-CG 4.04Å; R344-E348 VanDerWaalsContact CD-OE2 3.28Å; R344-E348 WeakPolarHBondContact CD-OE2 3.01Å; R344-E348 IonicContact CZ-OE2 3.6Å; R344-E348 IonicContact NE-OE2 4Å; R344-E348 IonicContact NH1-OE2 2.81Å; R344-E348 PolarHBondContact NH1-OE2 2.74Å; R344-E348 WeakPolarHBondContact O-CB 3.05Å; R344-E348 PolarHBondContact O-N 3.11Å; E348-F350 HydrophobicContact CB-CD2 4.45Å; E348-F350 HydrophobicContact CG-CD2 3.92Å; E348-F350 HydrophobicContact CG-CE2 3.77Å; E348-H366 VanDerWaalsContact O-CB 3.27Å; E348-H366 WeakPolarHBondContact O-CB 3.25Å; E348-H366 PolarHBondContact O-ND1 3.38Å; E348-N367 PolarHBondContact O-N 2.82Å; E348-N367 PolarHBondContact O-ND2 3.08Å; E348-N367 PolarHBondContact O-OD1 3.35Å; E348-N367 VanDerWaalsContact O-OD1 3.06Å
349G98.4Very high97.9Very high0 Ų026.9 Ų26.90%014%0.143CC..THydrogen-bonded Turntrans106.329.5165.800000115.1N345 V346 L347 T364 N367N345-G349 PolarHBondContact O-N 3.22Å; V346-G349 PolarHBondContact O-N 3.3Å; L347-G349 VanDerWaalsContact C-N 3.26Å; L347-G349 PolarHBondContact O-N 3.49Å; G349-T364 VanDerWaalsContact CA-O 3.32Å; G349-T364 WeakPolarHBondContact CA-O 2.78Å; G349-T364 WeakPolarHBondContact CA-OG1 2.97Å; G349-T364 PolarHBondContact O-N 3.05Å; G349-T364 PolarHBondContact O-OG1 3.5Å; G349-N367 PolarHBondContact O-ND2 3.16Å
350F98.1Very high97.8Very high40 Ų4031.7 Ų31.718%0.17517%0.174CC..SBendtrans-94.2-15.7167-64.1-79.5000112.5E206 R337 N345 E348 A358 V359 N367E206-F350 HydrophobicContact CB-CE2 4.41Å; E206-F350 HydrophobicContact CG-CE2 3.9Å; E206-F350 HydrophobicContact CG-CZ 3.78Å; R337-F350 HydrophobicContact CB-CB 4.14Å; R337-F350 HydrophobicContact CB-CD1 3.87Å; R337-F350 HydrophobicContact CB-CD2 3.87Å; R337-F350 HydrophobicContact CB-CE1 4.17Å; R337-F350 HydrophobicContact CB-CE2 4.18Å; R337-F350 HydrophobicContact CB-CG 3.7Å; R337-F350 HydrophobicContact CB-CZ 4.32Å; R337-F350 WeakPolarHBondContact O-CB 3.1Å; N345-F350 PolarHBondContact O-N 3.03Å; N345-F350 VanDerWaalsContact O-N 3.16Å; N345-F350 WeakPolarHBondContact OD1-CB 2.81Å; E348-F350 HydrophobicContact CB-CD2 4.45Å; E348-F350 HydrophobicContact CG-CD2 3.92Å; E348-F350 HydrophobicContact CG-CE2 3.77Å; F350-A358 WeakPolarHBondContact O-CA 3.45Å; F350-V359 PolarHBondContact O-N 2.98Å; F350-N367 WeakPolarHBondContact CE2-ND2 2.96Å; F350-N367 WeakPolarHBondContact CZ-ND2 3.47Å
351A97.9Very high97.5Very high0 Ų031.7 Ų31.70%019%0.19CC..BIsolated β-bridgetrans-112153.2174.400000112.3N345 V346 Q357 T364N345-A351 PolarHBondContact O-N 3.11Å; V346-A351 HydrophobicContact CB-CB 4.45Å; V346-A351 HydrophobicContact CG2-CB 3.58Å; A351-Q357 CarbonylContact C-O 3.41Å; A351-Q357 VanDerWaalsContact CA-O 3.27Å; A351-Q357 WeakPolarHBondContact CA-O 3.35Å; A351-Q357 WeakPolarHBondContact CB-O 3.42Å; A351-T364 PolarHBondContact O-OG1 2.84Å
352S97.6Very high97.4Very high17 Ų1731.7 Ų31.712%0.11919%0.189CC..  trans-66.9128.2179.1170.30000110.6E354 T355 G356 Q357S352-E354 PolarHBondContact O-N 3.07Å; S352-E354 VanDerWaalsContact O-N 3.16Å; S352-E354 PolarHBondContact OG-N 3.03Å; S352-E354 VanDerWaalsContact OG-N 3.09Å; S352-T355 WeakPolarHBondContact CB-OG1 3.21Å; S352-T355 PolarHBondContact OG-N 3.5Å; S352-G356 VanDerWaalsContact O-CA 3.26Å; S352-G356 WeakPolarHBondContact O-CA 3.17Å; S352-G356 PolarHBondContact O-N 3.44Å; S352-Q357 PolarHBondContact N-O 3Å
353P97.4Very high97.3Very high8 Ų831.9 Ų31.95%0.05219%0.19CC..THydrogen-bonded Turntrans-78.514.6172.136.7-37.9000112.9D320 F323 V346 M365D320-P353 HydrophobicContact CB-CB 3.69Å; D320-P353 HydrophobicContact CB-CG 3.81Å; F323-P353 WeakPolarHBondContact CB-O 3.01Å; F323-P353 WeakPolarHBondContact CD1-O 3.49Å; F323-P353 WeakPolarHBondContact CG-O 2.99Å; V346-P353 HydrophobicContact CG1-CB 4.02Å; P353-M365 HydrophobicContact CB-CG 3.91Å; P353-M365 HydrophobicContact CB-SD 3.78Å; P353-M365 HydrophobicContact CG-CG 4.11Å; P353-M365 HydrophobicContact CG-SD 4.02Å
354E97.1Very high97.3Very high123 Ų12332.8 Ų32.858%0.57520%0.196SC*.THydrogen-bonded Turntrans-112.9-31.4173.2-61.7174.9-171.700111.6R314 F323 S352R314-E354 IonicContact CZ-OE1 2.85Å; R314-E354 IonicContact NH2-OE1 3.58Å; R314-E354 PolarHBondContact NH2-OE1 3.5Å; F323-E354 WeakPolarHBondContact CE2-O 3.26Å; S352-E354 PolarHBondContact O-N 3.07Å; S352-E354 VanDerWaalsContact O-N 3.16Å; S352-E354 PolarHBondContact OG-N 3.03Å; S352-E354 VanDerWaalsContact OG-N 3.09Å
355T97.9Very high97.3Very high75 Ų7532.8 Ų32.846%0.4620%0.196SC..THydrogen-bonded Turntrans-122.1-13.8-17567.60000114M341 S352 Q357M341-T355 VanDerWaalsContact SD-O 3.4Å; S352-T355 WeakPolarHBondContact CB-OG1 3.21Å; S352-T355 PolarHBondContact OG-N 3.5Å; T355-Q357 PolarHBondContact O-N 3.13Å; T355-Q357 PolarHBondContact OG1-N 2.9Å
356G97.7Very high97.3Very high0 Ų033 Ų330%020%0.197CC..  trans70.13.1-172.900000114.5N340 M341 S352N340-G356 CarbonylContact C-O 3.48Å; N340-G356 WeakPolarHBondContact CA-O 3.42Å; M341-G356 PolarHBondContact N-O 3.34Å; S352-G356 VanDerWaalsContact O-CA 3.26Å; S352-G356 WeakPolarHBondContact O-CA 3.17Å; S352-G356 PolarHBondContact O-N 3.44Å
357Q98.2Very high97.3Very high84 Ų8434 Ų3439%0.39320%0.202SC..  trans-88.1139.7-178.8-58.7-63.8-49.900111N340 A351 S352 T355 V359N340-Q357 PolarHBondContact ND2-OE1 2.76Å; N340-Q357 WeakPolarHBondContact OD1-CA 3.37Å; N340-Q357 PolarHBondContact OD1-OE1 2.59Å; A351-Q357 CarbonylContact C-O 3.41Å; A351-Q357 VanDerWaalsContact CA-O 3.27Å; A351-Q357 WeakPolarHBondContact CA-O 3.35Å; A351-Q357 WeakPolarHBondContact CB-O 3.42Å; S352-Q357 PolarHBondContact N-O 3Å; T355-Q357 PolarHBondContact O-N 3.13Å; T355-Q357 PolarHBondContact OG1-N 2.9Å; Q357-V359 WeakPolarHBondContact O-CG2 3.49Å
358A97.1Very high97.2Very high23 Ų2334 Ų3419%0.1920%0.203CC..BIsolated β-bridgetrans-57.9134.3171.400000110.5N340 F350N340-A358 PolarHBondContact OD1-N 3.2Å; F350-A358 WeakPolarHBondContact O-CA 3.45Å
359V94.8Very high97.2Very high40 Ų4034 Ų3424%0.24220%0.202CC..  trans-125.288.6-178.2-168.30000109.4F350 Q357 G361 Q362F350-V359 PolarHBondContact O-N 2.98Å; Q357-V359 WeakPolarHBondContact O-CG2 3.49Å; V359-G361 PolarHBondContact O-N 3.47Å; V359-Q362 HydrophobicContact CB-CB 4.2Å; V359-Q362 HydrophobicContact CG1-CB 3.89Å; V359-Q362 HydrophobicContact CG1-CG 3.76Å; V359-Q362 PolarHBondContact O-N 3.17Å; V359-Q362 VanDerWaalsContact O-N 3.11Å
360P93.6Very high97.2Very high105 Ų10534.7 Ų34.768%0.68221%0.206SC*.THydrogen-bonded Turntrans-53.8134.2-179.7-26.935000112.3Q362P360-Q362 VanDerWaalsContact C-N 3.26Å; P360-Q362 PolarHBondContact O-N 3.5Å
361G92.9Very high97.2Very high67 Ų6733.4 Ų33.469%0.69120%0.201SC*.THydrogen-bonded Turntrans81.3-6.1179.500000115.3V359V359-G361 PolarHBondContact O-N 3.47Å
362Q95.4Very high97.2Very high82 Ų8234 Ų3438%0.38320%0.203SC..  trans-101.4157.8170-67.7-167.619.300111.8R311 V359 P360R311-Q362 WeakPolarHBondContact O-CA 3.16Å; V359-Q362 HydrophobicContact CB-CB 4.2Å; V359-Q362 HydrophobicContact CG1-CB 3.89Å; V359-Q362 HydrophobicContact CG1-CG 3.76Å; V359-Q362 PolarHBondContact O-N 3.17Å; V359-Q362 VanDerWaalsContact O-N 3.11Å; P360-Q362 VanDerWaalsContact C-N 3.26Å; P360-Q362 PolarHBondContact O-N 3.5Å
363S97.4Very high97.2Very high4 Ų433.1 Ų33.13%0.02820%0.198CC..  trans-130.8116.3175-65.10000108.5R311 S368R311-S363 PolarHBondContact NE-OG 3.29Å; R311-S363 PolarHBondContact O-N 3Å; S363-S368 WeakPolarHBondContact O-CB 3.18Å
364T97.7Very high97.3Very high19 Ų1935.4 Ų35.412%0.11721%0.209CC..  trans-112.1-179.2-179.865.60000109.6G349 A351 H366 N367 S368G349-T364 VanDerWaalsContact CA-O 3.32Å; G349-T364 WeakPolarHBondContact CA-O 2.78Å; G349-T364 WeakPolarHBondContact CA-OG1 2.97Å; G349-T364 PolarHBondContact O-N 3.05Å; G349-T364 PolarHBondContact O-OG1 3.5Å; A351-T364 PolarHBondContact O-OG1 2.84Å; T364-H366 PolarHBondContact O-N 3.32Å; T364-N367 PolarHBondContact O-N 3.32Å; T364-S368 PolarHBondContact O-N 3.4Å
365M98.1Very high97.3Very high1 Ų130.5 Ų30.51%0.00519%0.192CC..Hα-helixtrans42.6-121.9169-58.7-57.6-76.600114.5W241 P316 D320 V321 A324 V346 L347 P353 S368W241-M365 HydrophobicContact CH2-CE 4.47Å; P316-M365 HydrophobicContact CB-SD 3.67Å; P316-M365 HydrophobicContact CG-SD 4.29Å; D320-M365 HydrophobicContact CB-CE 4.42Å; D320-M365 HydrophobicContact CB-SD 3.57Å; D320-M365 VanDerWaalsContact CB-SD 3.57Å; V321-M365 HydrophobicContact CB-CE 4.42Å; V321-M365 HydrophobicContact CG2-CE 3.79Å; A324-M365 HydrophobicContact CB-CE 4.23Å; V346-M365 WeakPolarHBondContact O-CB 3.5Å; V346-M365 WeakPolarHBondContact O-CG 3.44Å; L347-M365 HydrophobicContact CD1-CE 4.08Å; L347-M365 WeakPolarHBondContact O-CB 3.46Å; P353-M365 HydrophobicContact CB-CG 3.91Å; P353-M365 HydrophobicContact CB-SD 3.78Å; P353-M365 HydrophobicContact CG-CG 4.11Å; P353-M365 HydrophobicContact CG-SD 4.02Å; M365-S368 PolarHBondContact O-N 2.82Å; M365-S368 PolarHBondContact O-OG 3.01Å
366H98.8Very high97.3Very high4 Ų427.6 Ų27.62%0.01918%0.175CC..Hα-helixtrans-54.4-55.5176.9156.6-89.6000112.4F210 L347 E348 T364 S368 L369 H370 H392 H393 I396F210-H366 AromaticContact CE2-CE1 3.74Å; F210-H366 AromaticContact CE2-NE2 3.74Å; F210-H366 HydrophobicContact CZ-CB 4.31Å; F210-H366 AromaticContact CZ-CD2 3.7Å; F210-H366 AromaticContact CZ-CE1 3.86Å; F210-H366 AromaticContact CZ-CG 3.73Å; F210-H366 AromaticContact CZ-ND1 3.83Å; F210-H366 AromaticContact CZ-NE2 3.76Å; L347-H366 VanDerWaalsContact O-CB 3.3Å; L347-H366 WeakPolarHBondContact O-CB 3.28Å; L347-H366 PolarHBondContact O-N 2.83Å; L347-H366 VanDerWaalsContact O-N 3.15Å; E348-H366 VanDerWaalsContact O-CB 3.27Å; E348-H366 WeakPolarHBondContact O-CB 3.25Å; E348-H366 PolarHBondContact O-ND1 3.38Å; T364-H366 PolarHBondContact O-N 3.32Å; H366-S368 PolarHBondContact O-N 3.11Å; H366-S368 VanDerWaalsContact O-N 3.1Å; H366-L369 PolarHBondContact O-N 2.99Å; H366-H370 AromaticContact CD2-CD2 3.81Å; H366-H370 AromaticContact CD2-NE2 3.76Å; H366-H370 AromaticContact CE1-CD2 3.68Å; H366-H370 AromaticContact CE1-NE2 3.79Å; H366-H370 AromaticContact NE2-CD2 3.48Å; H366-H370 PolarHBondContact NE2-CD2 2.03Å; H366-H370 AromaticContact NE2-NE2 3.21Å; H366-H370 PolarHBondContact NE2-NE2 2.99Å; H366-H370 PolarHBondContact O-N 3.39Å; H366-H392 AromaticContact CD2-CD2 3.65Å; H366-H392 AromaticContact CD2-NE2 3.05Å; H366-H392 PolarHBondContact CD2-NE2 2.85Å; H366-H392 AromaticContact CG-NE2 3.61Å; H366-H392 AromaticContact NE2-NE2 3.95Å; H366-H392 PolarHBondContact O-NE2 2.8Å; H366-H393 AromaticContact CD2-CE1 3.66Å; H366-H393 AromaticContact NE2-CE1 3.04Å; H366-H393 PolarHBondContact NE2-CE1 3.23Å; H366-H393 AromaticContact NE2-ND1 3.98Å; H366-H393 AromaticContact NE2-NE2 3.39Å; H366-H393 PolarHBondContact NE2-NE2 3.02Å; H366-I396 HydrophobicContact CB-CD1 3.68Å; H366-I396 HydrophobicContact CB-CG1 4.12Å
367N98.7Very high97.2Very high21 Ų2127.6 Ų27.611%0.11218%0.175CC..Hα-helixtrans-56.9-32.6-178.5-71.2-14.6000113E348 G349 F350 T364 L369 H370 V371E348-N367 PolarHBondContact O-N 2.82Å; E348-N367 PolarHBondContact O-ND2 3.08Å; E348-N367 PolarHBondContact O-OD1 3.35Å; E348-N367 VanDerWaalsContact O-OD1 3.06Å; G349-N367 PolarHBondContact O-ND2 3.16Å; F350-N367 WeakPolarHBondContact CE2-ND2 2.96Å; F350-N367 WeakPolarHBondContact CZ-ND2 3.47Å; T364-N367 PolarHBondContact O-N 3.32Å; N367-L369 VanDerWaalsContact C-N 3.34Å; N367-L369 PolarHBondContact O-N 2.97Å; N367-H370 PolarHBondContact O-N 3.09Å; N367-V371 WeakPolarHBondContact O-CG2 3.39Å; N367-V371 PolarHBondContact O-N 3.25Å; N367-V371 VanDerWaalsContact O-N 3.11Å
368S98.1Very high97.2Very high1 Ų125.7 Ų25.71%0.00717%0.171CC..Hα-helixtrans-63.5-38179.574.90000112.7P316 S363 T364 M365 H366 F372P316-S368 WeakPolarHBondContact CD-OG 3.37Å; P316-S368 VanDerWaalsContact CG-OG 3.27Å; P316-S368 WeakPolarHBondContact CG-OG 3.45Å; S363-S368 WeakPolarHBondContact O-CB 3.18Å; T364-S368 PolarHBondContact O-N 3.4Å; M365-S368 PolarHBondContact O-N 2.82Å; M365-S368 PolarHBondContact O-OG 3.01Å; H366-S368 PolarHBondContact O-N 3.11Å; H366-S368 VanDerWaalsContact O-N 3.1Å; S368-F372 WeakPolarHBondContact O-CB 3.21Å; S368-F372 PolarHBondContact O-N 3.44Å
369L98.3Very high97.1Very high0 Ų026.8 Ų26.80%017%0.173CC..Hα-helixtrans-72.2-41.5179.7-16675.3000110.9W239 W241 L315 H366 N367 V371 F372 M373 H392W239-L369 HydrophobicContact CE3-CD2 4.2Å; W239-L369 HydrophobicContact CH2-CD1 3.89Å; W239-L369 HydrophobicContact CZ3-CD1 3.88Å; W239-L369 HydrophobicContact CZ3-CD2 3.82Å; W239-L369 HydrophobicContact CZ3-CG 4.36Å; W241-L369 HydrophobicContact CB-CD1 4.44Å; W241-L369 HydrophobicContact CG-CD1 4.44Å; W241-L369 HydrophobicContact CG-CD2 4.15Å; L315-L369 HydrophobicContact CD2-CD1 3.66Å; H366-L369 PolarHBondContact O-N 2.99Å; N367-L369 VanDerWaalsContact C-N 3.34Å; N367-L369 PolarHBondContact O-N 2.97Å; L369-V371 VanDerWaalsContact C-N 3.31Å; L369-V371 PolarHBondContact O-N 3.48Å; L369-F372 HydrophobicContact CD1-CD1 4.28Å; L369-F372 PolarHBondContact O-N 3.44Å; L369-M373 HydrophobicContact CD1-CE 3.85Å; L369-M373 HydrophobicContact CD2-CE 4.44Å; L369-M373 HydrophobicContact CG-CE 4.01Å; L369-M373 WeakPolarHBondContact O-CG 3.38Å; L369-M373 PolarHBondContact O-N 3.3Å; L369-H392 HydrophobicContact CD2-CB 3.87Å; L369-H392 WeakPolarHBondContact CD2-ND1 3.4Å
370H98.6Very high97.2Very high15 Ų1528.6 Ų28.67%0.06918%0.184CC..Hα-helixtrans-53.9-48.2174.1-84.5-85.4000112H366 N367 M377 S378 F389 H392 H393H366-H370 AromaticContact CD2-CD2 3.81Å; H366-H370 AromaticContact CD2-NE2 3.76Å; H366-H370 AromaticContact CE1-CD2 3.68Å; H366-H370 AromaticContact CE1-NE2 3.79Å; H366-H370 AromaticContact NE2-CD2 3.48Å; H366-H370 PolarHBondContact NE2-CD2 2.03Å; H366-H370 AromaticContact NE2-NE2 3.21Å; H366-H370 PolarHBondContact NE2-NE2 2.99Å; H366-H370 PolarHBondContact O-N 3.39Å; N367-H370 PolarHBondContact O-N 3.09Å; H370-M377 WeakPolarHBondContact CB-O 3.19Å; H370-M377 PolarHBondContact ND1-O 2.92Å; H370-M377 CarbonylContact O-C 3.34Å; H370-S378 WeakPolarHBondContact O-CA 3.2Å; H370-S378 PolarHBondContact O-N 2.83Å; H370-S378 PolarHBondContact O-OG 3.09Å; H370-F389 AromaticContact CE1-CD2 3.9Å; H370-H392 AromaticContact CD2-CD2 3.64Å; H370-H392 AromaticContact CD2-NE2 3.57Å; H370-H392 AromaticContact NE2-CD2 3.32Å; H370-H392 PolarHBondContact NE2-CD2 3.15Å; H370-H392 VanDerWaalsContact NE2-CD2 3.32Å; H370-H392 AromaticContact NE2-NE2 3.71Å; H370-H393 AromaticContact CE1-NE2 3.74Å; H370-H393 AromaticContact NE2-NE2 3.28Å; H370-H393 PolarHBondContact NE2-NE2 3.11Å
371V98.3Very high97.2Very high13 Ų1324.2 Ų24.28%0.07916%0.155CC..Hα-helixtrans-73.2-38.9179.5174.40000111.6H307 R311 V312 N367 L369 M373 N374 S378H307-V371 HydrophobicContact CB-CG1 4.2Å; H307-V371 WeakPolarHBondContact CB-O 3.45Å; R311-V371 HydrophobicContact CG-CG1 4.43Å; V312-V371 HydrophobicContact CB-CG1 4.45Å; V312-V371 HydrophobicContact CG2-CB 3.62Å; V312-V371 HydrophobicContact CG2-CG1 3.55Å; V312-V371 HydrophobicContact CG2-CG2 4.38Å; N367-V371 WeakPolarHBondContact O-CG2 3.39Å; N367-V371 PolarHBondContact O-N 3.25Å; N367-V371 VanDerWaalsContact O-N 3.11Å; L369-V371 VanDerWaalsContact C-N 3.31Å; L369-V371 PolarHBondContact O-N 3.48Å; V371-M373 PolarHBondContact O-N 2.56Å; V371-N374 PolarHBondContact O-N 3.44Å; V371-S378 PolarHBondContact O-OG 2.85Å
372F98.3Very high97.4Very high11 Ų1121.1 Ų21.15%0.04812%0.122CC..Hα-helixtrans-55.9-35178.3169.4-96.5000113C247 P304 G305 H307 L315 S368 L369 N374C247-F372 HydrophobicContact CB-CE1 4.26Å; P304-F372 CarbonylContact C-O 3.32Å; P304-F372 VanDerWaalsContact CA-O 3.28Å; P304-F372 WeakPolarHBondContact CA-O 3.43Å; P304-F372 HydrophobicContact CB-CD1 4.18Å; P304-F372 HydrophobicContact CB-CE1 3.6Å; P304-F372 HydrophobicContact CB-CZ 4.04Å; G305-F372 VanDerWaalsContact CA-CE2 3.44Å; G305-F372 PolarHBondContact N-O 3.34Å; H307-F372 AromaticContact CE1-CD2 3.53Å; H307-F372 AromaticContact ND1-CD2 3.6Å; L315-F372 HydrophobicContact CD1-CD1 4.12Å; L315-F372 HydrophobicContact CD1-CD2 4.09Å; L315-F372 HydrophobicContact CD1-CE1 3.94Å; L315-F372 HydrophobicContact CD1-CE2 3.92Å; L315-F372 HydrophobicContact CD1-CG 4.2Å; L315-F372 HydrophobicContact CD1-CZ 3.86Å; L315-F372 HydrophobicContact CD2-CB 3.72Å; L315-F372 HydrophobicContact CD2-CD1 4Å; L315-F372 HydrophobicContact CD2-CD2 3.95Å; L315-F372 HydrophobicContact CD2-CG 3.62Å; L315-F372 HydrophobicContact CG-CD1 4.46Å; L315-F372 HydrophobicContact CG-CD2 3.93Å; L315-F372 HydrophobicContact CG-CE2 4.19Å; L315-F372 HydrophobicContact CG-CG 4.09Å; S368-F372 WeakPolarHBondContact O-CB 3.21Å; S368-F372 PolarHBondContact O-N 3.44Å; L369-F372 HydrophobicContact CD1-CD1 4.28Å; L369-F372 PolarHBondContact O-N 3.44Å; F372-N374 PolarHBondContact O-N 3.47Å
373M98.1Very high97.5Very high0 Ų017.2 Ų17.20%010%0.104CC..THydrogen-bonded Turntrans-66.1-20.8179.5-69.9-62.6160.800113.7W239 C247 R302 N303 P304 L369 V371 M377 I388W239-M373 HydrophobicContact CH2-CE 3.74Å; W239-M373 HydrophobicContact CZ3-CE 3.45Å; W239-M373 VanDerWaalsContact CZ3-CE 3.45Å; C247-M373 HydrophobicContact CB-CE 4.32Å; R302-M373 HydrophobicContact CG-SD 4.45Å; N303-M373 CarbonylContact C-O 3.55Å; N303-M373 PolarHBondContact N-O 3.21Å; P304-M373 HydrophobicContact CB-SD 4.08Å; P304-M373 HydrophobicContact CG-SD 3.81Å; L369-M373 HydrophobicContact CD1-CE 3.85Å; L369-M373 HydrophobicContact CD2-CE 4.44Å; L369-M373 HydrophobicContact CG-CE 4.01Å; L369-M373 WeakPolarHBondContact O-CG 3.38Å; L369-M373 PolarHBondContact O-N 3.3Å; V371-M373 PolarHBondContact O-N 2.56Å; M373-M377 HydrophobicContact CB-CB 3.54Å; M373-M377 HydrophobicContact CB-CG 4.07Å; M373-M377 HydrophobicContact CG-CB 3.97Å; M373-M377 HydrophobicContact CG-CG 4.03Å; M373-I388 HydrophobicContact CE-CD1 4.22Å; M373-I388 HydrophobicContact CE-CG2 4.04Å; M373-I388 HydrophobicContact SD-CD1 4Å
374N97.7Very high97.5Very high55 Ų5517 Ų1729%0.29410%0.103SC..  trans42.570.5175.8-173.640000113.1N303 N306 H307 V371 F372 S378N303-N374 PolarHBondContact N-O 2.03Å; N303-N374 VanDerWaalsContact N-O 3.11Å; N303-N374 WeakPolarHBondContact O-CB 3.18Å; N306-N374 PolarHBondContact O-ND2 3.22Å; H307-N374 HydrophobicContact CB-CB 4.15Å; V371-N374 PolarHBondContact O-N 3.44Å; F372-N374 PolarHBondContact O-N 3.47Å; N374-S378 WeakPolarHBondContact CA-OG 3.37Å; N374-S378 PolarHBondContact N-OG 3.16Å
375G97Very high97.6Very high21 Ų2116.3 Ų16.322%0.21610%0.098CC..SBendtrans173.7-142.8-174.600000111.1L301 M377 S378L301-G375 CarbonylContact O-C 3.35Å; L301-G375 WeakPolarHBondContact O-CA 3.36Å; G375-M377 VanDerWaalsContact C-N 3.27Å; G375-M377 PolarHBondContact O-N 2.92Å; G375-S378 PolarHBondContact N-OG 2.82Å; G375-S378 WeakPolarHBondContact O-CB 3.34Å; G375-S378 PolarHBondContact O-N 2.75Å
376S97.8Very high97.6Very high13 Ų1316.2 Ų16.29%0.09110%0.098CC..G310 helixtrans-55.9-40.7-178.6-61.10000112.4L301 S378 N379 S383L301-S376 PolarHBondContact N-OG 2.05Å; L301-S376 VanDerWaalsContact N-OG 3.08Å; L301-S376 PolarHBondContact O-N 3.47Å; L301-S376 PolarHBondContact O-OG 3.01Å; S376-S378 PolarHBondContact O-N 3.12Å; S376-S378 VanDerWaalsContact O-N 3.12Å; S376-N379 PolarHBondContact O-N 2.79Å; S376-S383 WeakPolarHBondContact O-CA 3.38Å
377M97.6Very high97.6Very high1 Ų116 Ų161%0.00510%0.097CC..G310 helixtrans-57.9-22.2173.9-84.5-67.8-72.900114.8H370 M373 G375 D386 F389 H392H370-M377 WeakPolarHBondContact CB-O 3.19Å; H370-M377 PolarHBondContact ND1-O 2.92Å; H370-M377 CarbonylContact O-C 3.34Å; M373-M377 HydrophobicContact CB-CB 3.54Å; M373-M377 HydrophobicContact CB-CG 4.07Å; M373-M377 HydrophobicContact CG-CB 3.97Å; M373-M377 HydrophobicContact CG-CG 4.03Å; G375-M377 VanDerWaalsContact C-N 3.27Å; G375-M377 PolarHBondContact O-N 2.92Å; M377-D386 HydrophobicContact CG-CB 3.51Å; M377-D386 HydrophobicContact SD-CB 3.92Å; M377-F389 HydrophobicContact SD-CB 3.87Å; M377-F389 HydrophobicContact SD-CD2 4.34Å; M377-H392 HydrophobicContact CE-CB 4.49Å
378S97.1Very high97.6Very high44 Ų4415 Ų1531%0.3089%0.092SC..G310 helixtrans-89.4-7.9-175.3-49.10000113.5H370 V371 N374 G375 S376H370-S378 WeakPolarHBondContact O-CA 3.2Å; H370-S378 PolarHBondContact O-N 2.83Å; H370-S378 PolarHBondContact O-OG 3.09Å; V371-S378 PolarHBondContact O-OG 2.85Å; N374-S378 WeakPolarHBondContact CA-OG 3.37Å; N374-S378 PolarHBondContact N-OG 3.16Å; G375-S378 PolarHBondContact N-OG 2.82Å; G375-S378 WeakPolarHBondContact O-CB 3.34Å; G375-S378 PolarHBondContact O-N 2.75Å; S376-S378 PolarHBondContact O-N 3.12Å; S376-S378 VanDerWaalsContact O-N 3.12Å
379N95.4Very high97.7Very high46 Ų4615 Ų1525%0.2469%0.092CC..SBendtrans-95117.8170.9178.3-51.9000107.8S280 S376 Q381 G382 S383S280-N379 PolarHBondContact O-ND2 3.42Å; S376-N379 PolarHBondContact O-N 2.79Å; N379-Q381 PolarHBondContact O-N 3.18Å; N379-Q381 PolarHBondContact OD1-N 3.16Å; N379-Q381 VanDerWaalsContact OD1-N 3.15Å; N379-G382 CarbonylContact O-C 3.55Å; N379-G382 PolarHBondContact O-N 3.31Å; N379-G382 PolarHBondContact OD1-N 3.16Å; N379-S383 VanDerWaalsContact O-CA 3.27Å; N379-S383 WeakPolarHBondContact O-CA 3.27Å; N379-S383 WeakPolarHBondContact O-CB 3.37Å; N379-S383 PolarHBondContact O-N 3.04Å
380V95.9Very high97.7Very high77 Ų7715 Ų1547%0.4679%0.092SC..THydrogen-bonded Turntrans-52.6-59.7-176.5177.50000110.4H182 G382 S383H182-V380 PolarHBondContact CE1-O 3.28Å; H182-V380 PolarHBondContact ND1-O 3.27Å; H182-V380 VanDerWaalsContact ND1-O 3.11Å; V380-G382 VanDerWaalsContact C-N 3.3Å; V380-G382 PolarHBondContact O-N 2.8Å; V380-S383 WeakPolarHBondContact O-CB 3.29Å; V380-S383 PolarHBondContact O-N 2.74Å; V380-S383 PolarHBondContact O-OG 2.94Å
381Q94.9Very high97.7Very high14 Ų1414.3 Ų14.37%0.0659%0.088CC..THydrogen-bonded Turntrans-57.5-37.6-178.6-72.5172.911.300114.2Y183 S186 N379Y183-Q381 HydrophobicContact CD2-CB 4.05Å; Y183-Q381 HydrophobicContact CD2-CG 4.22Å; S186-Q381 PolarHBondContact O-NE2 2.03Å; S186-Q381 VanDerWaalsContact O-NE2 3.08Å; N379-Q381 PolarHBondContact O-N 3.18Å; N379-Q381 PolarHBondContact OD1-N 3.16Å; N379-Q381 VanDerWaalsContact OD1-N 3.15Å
382G95.6Very high97.7Very high1 Ų113.7 Ų13.71%0.018%0.084CC..THydrogen-bonded Turntrans-96.5-0.4-176.700000114.7N379 V380 A384 N385N379-G382 CarbonylContact O-C 3.55Å; N379-G382 PolarHBondContact O-N 3.31Å; N379-G382 PolarHBondContact OD1-N 3.16Å; V380-G382 VanDerWaalsContact C-N 3.3Å; V380-G382 PolarHBondContact O-N 2.8Å; G382-A384 VanDerWaalsContact C-N 3.32Å; G382-A384 PolarHBondContact O-N 3.42Å; G382-N385 VanDerWaalsContact O-CB 3.3Å; G382-N385 WeakPolarHBondContact O-CB 3.2Å; G382-N385 PolarHBondContact O-N 3.06Å; G382-N385 VanDerWaalsContact O-N 3.11Å; G382-N385 PolarHBondContact O-ND2 3.48Å
383S98.4Very high97.8Very high1 Ų113.2 Ų13.21%0.0078%0.083CC..G310 helixtrans-62.5-38-166.957.10000113.1H182 S376 N379 V380 N385 D386 F389H182-S383 PolarHBondContact CE1-OG 3.06Å; S376-S383 WeakPolarHBondContact O-CA 3.38Å; N379-S383 VanDerWaalsContact O-CA 3.27Å; N379-S383 WeakPolarHBondContact O-CA 3.27Å; N379-S383 WeakPolarHBondContact O-CB 3.37Å; N379-S383 PolarHBondContact O-N 3.04Å; V380-S383 WeakPolarHBondContact O-CB 3.29Å; V380-S383 PolarHBondContact O-N 2.74Å; V380-S383 PolarHBondContact O-OG 2.94Å; S383-N385 PolarHBondContact O-N 3.31Å; S383-N385 VanDerWaalsContact O-N 3.1Å; S383-D386 PolarHBondContact O-N 2.84Å; S383-D386 VanDerWaalsContact O-N 3.12Å; S383-F389 WeakPolarHBondContact OG-CE2 3.43Å
384A98.4Very high97.8Very high0 Ų013.2 Ų13.20%08%0.083CC..G310 helixtrans-63.7-13.7179.200000114.4Y175 V179 H182 W221 G382 D386 F389Y175-A384 VanDerWaalsContact CE1-O 3.27Å; Y175-A384 WeakPolarHBondContact CE1-O 3.19Å; Y175-A384 PolarHBondContact OH-O 3.38Å; V179-A384 HydrophobicContact CG2-CB 4.24Å; H182-A384 HydrophobicContact CB-CB 4.16Å; W221-A384 HydrophobicContact CH2-CB 4.36Å; W221-A384 HydrophobicContact CZ3-CB 4.38Å; G382-A384 VanDerWaalsContact C-N 3.32Å; G382-A384 PolarHBondContact O-N 3.42Å; A384-D386 PolarHBondContact O-N 3.19Å; A384-F389 HydrophobicContact CB-CD1 4.34Å; A384-F389 HydrophobicContact CB-CD2 4.03Å; A384-F389 HydrophobicContact CB-CE2 4.16Å; A384-F389 HydrophobicContact CB-CG 4.12Å; A384-F389 HydrophobicContact CB-CZ 4.4Å
385N98.7Very high97.9Very high3 Ų310.6 Ų10.62%0.0167%0.069CC..G310 helixtrans-59.8-29.8171.8-77.5-79.7000112.4V179 V277 I278 L300 G382 S383V179-N385 VanDerWaalsContact CG1-ND2 3.29Å; V179-N385 WeakPolarHBondContact CG1-ND2 3.45Å; V277-N385 WeakPolarHBondContact CA-OD1 3.48Å; V277-N385 HydrophobicContact CB-CB 4.12Å; V277-N385 HydrophobicContact CG1-CB 3.86Å; I278-N385 PolarHBondContact N-OD1 3.21Å; I278-N385 PolarHBondContact O-ND2 2.98Å; L300-N385 HydrophobicContact CD1-CB 4.23Å; G382-N385 VanDerWaalsContact O-CB 3.3Å; G382-N385 WeakPolarHBondContact O-CB 3.2Å; G382-N385 PolarHBondContact O-N 3.06Å; G382-N385 VanDerWaalsContact O-N 3.11Å; G382-N385 PolarHBondContact O-ND2 3.48Å; S383-N385 PolarHBondContact O-N 3.31Å; S383-N385 VanDerWaalsContact O-N 3.1Å
386D98.8Very high98Very high0 Ų09.8 Ų9.80%06%0.059CC..SBendtrans-85.3124.4178.4-168-44.8000110.4L300 R302 M377 S383 A384 I388 F389L300-D386 HydrophobicContact CD1-CB 3.85Å; L300-D386 HydrophobicContact CD2-CB 4.49Å; R302-D386 IonicContact CZ-OD1 2.74Å; R302-D386 IonicContact CZ-OD2 3.69Å; R302-D386 IonicContact NE-OD1 2.66Å; R302-D386 IonicContact NE-OD2 2.68Å; R302-D386 PolarHBondContact NE-OD2 3.37Å; R302-D386 IonicContact NH2-OD1 2.75Å; R302-D386 PolarHBondContact NH2-OD1 3.26Å; R302-D386 IonicContact NH2-OD2 3.42Å; R302-D386 PolarHBondContact NH2-OD2 3.04Å; R302-D386 VanDerWaalsContact NH2-OD2 3.11Å; M377-D386 HydrophobicContact CG-CB 3.51Å; M377-D386 HydrophobicContact SD-CB 3.92Å; S383-D386 PolarHBondContact O-N 2.84Å; S383-D386 VanDerWaalsContact O-N 3.12Å; A384-D386 PolarHBondContact O-N 3.19Å; D386-I388 PolarHBondContact O-N 3.34Å; D386-I388 VanDerWaalsContact O-N 3.07Å; D386-I388 VanDerWaalsContact OD1-CB 3.3Å; D386-I388 WeakPolarHBondContact OD1-CB 3.27Å; D386-I388 WeakPolarHBondContact OD1-CG1 3.43Å; D386-I388 PolarHBondContact OD1-N 3.5Å; D386-F389 WeakPolarHBondContact O-CB 3.47Å; D386-F389 PolarHBondContact O-N 3.11Å
387P98.6Very high98Very high0 Ų09.4 Ų9.40%06%0.056CC..THydrogen-bonded Turntrans-63.8-15.2-179.228.9-38.6000114.3L139 Y175 M255 F272 F389 L390L139-P387 HydrophobicContact CD1-CB 3.67Å; Y175-P387 VanDerWaalsContact OH-CA 3.28Å; Y175-P387 WeakPolarHBondContact OH-CA 3.41Å; M255-P387 HydrophobicContact SD-CB 4.21Å; M255-P387 HydrophobicContact SD-CG 4.34Å; F272-P387 HydrophobicContact CD1-CB 4.42Å; F272-P387 HydrophobicContact CD1-CG 3.74Å; F272-P387 HydrophobicContact CD2-CG 4.13Å; F272-P387 HydrophobicContact CE1-CB 3.95Å; F272-P387 HydrophobicContact CE1-CG 3.73Å; F272-P387 HydrophobicContact CE2-CG 4.12Å; F272-P387 HydrophobicContact CG-CG 3.96Å; F272-P387 HydrophobicContact CZ-CB 4.09Å; F272-P387 HydrophobicContact CZ-CG 3.92Å; P387-F389 PolarHBondContact O-N 3.44Å; P387-L390 PolarHBondContact O-N 3.35Å
388I98.8Very high98.1Very high0 Ų09.4 Ų9.40%06%0.056CC..Hα-helixtrans-63.4-25.7171.3-66.5179.4000111.1W239 V249 M255 M373 D386 L390 L391 H392W239-I388 HydrophobicContact CE3-CG2 4.24Å; W239-I388 HydrophobicContact CZ3-CG2 4.16Å; V249-I388 HydrophobicContact CG2-CD1 3.98Å; V249-I388 HydrophobicContact CG2-CG1 4.15Å; M255-I388 HydrophobicContact CB-CD1 4.11Å; M255-I388 HydrophobicContact CB-CG1 3.71Å; M255-I388 HydrophobicContact CG-CG1 3.85Å; M373-I388 HydrophobicContact CE-CD1 4.22Å; M373-I388 HydrophobicContact CE-CG2 4.04Å; M373-I388 HydrophobicContact SD-CD1 4Å; D386-I388 PolarHBondContact O-N 3.34Å; D386-I388 VanDerWaalsContact O-N 3.07Å; D386-I388 VanDerWaalsContact OD1-CB 3.3Å; D386-I388 WeakPolarHBondContact OD1-CB 3.27Å; D386-I388 WeakPolarHBondContact OD1-CG1 3.43Å; D386-I388 PolarHBondContact OD1-N 3.5Å; I388-L390 VanDerWaalsContact C-N 3.26Å; I388-L390 PolarHBondContact O-N 3.1Å; I388-L391 PolarHBondContact O-N 3.31Å; I388-L391 VanDerWaalsContact O-N 3.13Å; I388-H392 WeakPolarHBondContact O-CB 3.49Å; I388-H392 PolarHBondContact O-N 3.17Å
389F98.9Very high98.1Very high0 Ų07.3 Ų7.30%04%0.041CC..Hα-helixtrans-49.4-48175.1-176-78.4000111.6H182 F217 W221 H370 M377 S383 A384 D386 P387 L391 H392 H393H182-F389 AromaticContact CD2-CZ 3.77Å; H182-F389 AromaticContact NE2-CE2 3.84Å; H182-F389 AromaticContact NE2-CZ 3.84Å; F217-F389 HydrophobicContact CD1-CE1 4.05Å; F217-F389 HydrophobicContact CE1-CD1 4.27Å; F217-F389 AromaticContact CE1-CE1 3.44Å; F217-F389 HydrophobicContact CE1-CE1 3.44Å; F217-F389 VanDerWaalsContact CE1-CE1 3.44Å; F217-F389 HydrophobicContact CE1-CZ 4.04Å; F217-F389 HydrophobicContact CZ-CE1 4.41Å; W221-F389 HydrophobicContact CZ3-CD1 4.31Å; H370-F389 AromaticContact CE1-CD2 3.9Å; M377-F389 HydrophobicContact SD-CB 3.87Å; M377-F389 HydrophobicContact SD-CD2 4.34Å; S383-F389 WeakPolarHBondContact OG-CE2 3.43Å; A384-F389 HydrophobicContact CB-CD1 4.34Å; A384-F389 HydrophobicContact CB-CD2 4.03Å; A384-F389 HydrophobicContact CB-CE2 4.16Å; A384-F389 HydrophobicContact CB-CG 4.12Å; A384-F389 HydrophobicContact CB-CZ 4.4Å; D386-F389 WeakPolarHBondContact O-CB 3.47Å; D386-F389 PolarHBondContact O-N 3.11Å; P387-F389 PolarHBondContact O-N 3.44Å; F389-L391 PolarHBondContact O-N 3.09Å; F389-H392 PolarHBondContact O-N 2.85Å; F389-H393 AromaticContact CD1-CD2 3.6Å; F389-H393 AromaticContact CD2-CD2 3.71Å; F389-H393 AromaticContact CD2-NE2 3.74Å; F389-H393 HydrophobicContact CE1-CB 4.25Å; F389-H393 AromaticContact CE1-CD2 3.28Å; F389-H393 WeakPolarHBondContact CE1-CD2 3.31Å; F389-H393 AromaticContact CE1-CG 3.75Å; F389-H393 AromaticContact CE1-NE2 3.75Å; F389-H393 AromaticContact CE2-CD2 3.48Å; F389-H393 VanDerWaalsContact CE2-CD2 3.48Å; F389-H393 WeakPolarHBondContact CE2-CD2 3.43Å; F389-H393 AromaticContact CE2-NE2 3.16Å; F389-H393 WeakPolarHBondContact CE2-NE2 3.3Å; F389-H393 AromaticContact CG-CD2 3.78Å; F389-H393 AromaticContact CZ-CD2 3.25Å; F389-H393 WeakPolarHBondContact CZ-CD2 3.17Å; F389-H393 AromaticContact CZ-CE1 3.79Å; F389-H393 AromaticContact CZ-CG 3.91Å; F389-H393 AromaticContact CZ-NE2 3.17Å; F389-H393 WeakPolarHBondContact CZ-NE2 3.4Å; F389-H393 PolarHBondContact O-CD2 3.11Å; F389-H393 PolarHBondContact O-N 3.2Å
390L98.9Very high98.3Very high0 Ų05.1 Ų5.10%03%0.03CC..Hα-helixtrans-60.6-46-179.4-75.3176.1000112.2F135 L139 Y175 L218 W221 I236 P387 I388 H392 A394F135-L390 HydrophobicContact CZ-CD1 4.3Å; L139-L390 HydrophobicContact CD1-CD1 4.21Å; L139-L390 HydrophobicContact CD2-CD1 3.55Å; Y175-L390 HydrophobicContact CE2-CD1 4.39Å; L218-L390 HydrophobicContact CD2-CD2 3.77Å; W221-L390 HydrophobicContact CD2-CD2 3.66Å; W221-L390 HydrophobicContact CD2-CG 4.49Å; W221-L390 HydrophobicContact CE3-CD2 3.39Å; W221-L390 HydrophobicContact CE3-CG 4.31Å; W221-L390 HydrophobicContact CG-CD2 4.25Å; W221-L390 HydrophobicContact CH2-CD2 4.32Å; W221-L390 HydrophobicContact CH2-CG 4.4Å; W221-L390 HydrophobicContact CZ2-CD1 4.37Å; W221-L390 HydrophobicContact CZ3-CD2 3.75Å; W221-L390 HydrophobicContact CZ3-CG 4.24Å; I236-L390 HydrophobicContact CD1-CD2 3.78Å; I236-L390 HydrophobicContact CG2-CB 3.96Å; I236-L390 HydrophobicContact CG2-CD2 4.36Å; P387-L390 PolarHBondContact O-N 3.35Å; I388-L390 VanDerWaalsContact C-N 3.26Å; I388-L390 PolarHBondContact O-N 3.1Å; L390-H392 VanDerWaalsContact C-N 3.32Å; L390-H392 PolarHBondContact O-N 3.24Å; L390-A394 WeakPolarHBondContact O-CB 3.13Å; L390-A394 PolarHBondContact O-N 2.83Å
391L98.9Very high98.4Very high0 Ų01.4 Ų1.40%01%0.007CC..Hα-helixtrans-64.9-39.8178.8-57-176.1000111.8I124 F135 P237 W239 V249 M255 I388 F389 F395I124-L391 HydrophobicContact CB-CD2 4.37Å; I124-L391 HydrophobicContact CD1-CD1 4.06Å; I124-L391 HydrophobicContact CD1-CD2 3.85Å; I124-L391 HydrophobicContact CG2-CD1 4.13Å; I124-L391 HydrophobicContact CG2-CD2 4.43Å; F135-L391 HydrophobicContact CE1-CD2 4.01Å; F135-L391 HydrophobicContact CZ-CD2 4.13Å; P237-L391 HydrophobicContact CB-CD2 4.43Å; P237-L391 HydrophobicContact CG-CD2 3.74Å; P237-L391 WeakPolarHBondContact O-CD2 3.02Å; W239-L391 HydrophobicContact CB-CB 3.83Å; W239-L391 HydrophobicContact CB-CD1 4.19Å; W239-L391 PolarHBondContact N-O 3.45Å; W239-L391 VanDerWaalsContact N-O 3.15Å; V249-L391 HydrophobicContact CB-CD1 4.27Å; V249-L391 HydrophobicContact CG1-CD1 4.08Å; V249-L391 HydrophobicContact CG2-CD1 4.28Å; M255-L391 HydrophobicContact CE-CD1 3.76Å; M255-L391 HydrophobicContact CE-CD2 4.4Å; M255-L391 HydrophobicContact CE-CG 4.36Å; M255-L391 HydrophobicContact CG-CD1 3.81Å; M255-L391 HydrophobicContact SD-CD1 4.11Å; I388-L391 PolarHBondContact O-N 3.31Å; I388-L391 VanDerWaalsContact O-N 3.13Å; F389-L391 PolarHBondContact O-N 3.09Å; L391-F395 PolarHBondContact O-N 3.29Å
392H98.9Very high98.6Very high0 Ų03.9 Ų3.90%02%0.016CC..Hα-helixtrans-66.3-55.8-179.6177.954000111.4W241 H366 L369 H370 M377 I388 F389 L390 A394 F395 I396W241-H392 AromaticContact CD1-ND1 3.76Å; W241-H392 AromaticContact CE2-ND1 3.98Å; W241-H392 AromaticContact NE1-CE1 3.6Å; W241-H392 AromaticContact NE1-ND1 3.11Å; W241-H392 PolarHBondContact NE1-ND1 2.73Å; W241-H392 VanDerWaalsContact NE1-ND1 3.11Å; H366-H392 AromaticContact CD2-CD2 3.65Å; H366-H392 AromaticContact CD2-NE2 3.05Å; H366-H392 PolarHBondContact CD2-NE2 2.85Å; H366-H392 AromaticContact CG-NE2 3.61Å; H366-H392 AromaticContact NE2-NE2 3.95Å; H366-H392 PolarHBondContact O-NE2 2.8Å; L369-H392 HydrophobicContact CD2-CB 3.87Å; L369-H392 WeakPolarHBondContact CD2-ND1 3.4Å; H370-H392 AromaticContact CD2-CD2 3.64Å; H370-H392 AromaticContact CD2-NE2 3.57Å; H370-H392 AromaticContact NE2-CD2 3.32Å; H370-H392 PolarHBondContact NE2-CD2 3.15Å; H370-H392 VanDerWaalsContact NE2-CD2 3.32Å; H370-H392 AromaticContact NE2-NE2 3.71Å; M377-H392 HydrophobicContact CE-CB 4.49Å; I388-H392 WeakPolarHBondContact O-CB 3.49Å; I388-H392 PolarHBondContact O-N 3.17Å; F389-H392 PolarHBondContact O-N 2.85Å; L390-H392 VanDerWaalsContact C-N 3.32Å; L390-H392 PolarHBondContact O-N 3.24Å; H392-A394 VanDerWaalsContact C-N 3.3Å; H392-A394 PolarHBondContact O-N 2.71Å; H392-F395 WeakPolarHBondContact O-CA 3.42Å; H392-F395 WeakPolarHBondContact O-CB 3.45Å; H392-F395 PolarHBondContact O-N 3.47Å; H392-I396 PolarHBondContact O-N 2.91Å
393H98.9Very high98.7Very high2 Ų23.8 Ų3.81%0.0092%0.015CC..Hα-helixtrans-67.8-31.1-178.2-79.3-90.1000112.2H214 L218 H366 H370 F389 F395 I396 D397H214-H393 AromaticContact CD2-CE1 3.23Å; H214-H393 PolarHBondContact CD2-CE1 3.33Å; H214-H393 AromaticContact CD2-ND1 3.16Å; H214-H393 PolarHBondContact CD2-ND1 2.82Å; H214-H393 AromaticContact CG-CE1 3.9Å; H214-H393 AromaticContact CG-ND1 3.57Å; H214-H393 AromaticContact NE2-CE1 3.41Å; H214-H393 PolarHBondContact NE2-CE1 3.26Å; H214-H393 AromaticContact NE2-ND1 3.84Å; L218-H393 HydrophobicContact CD1-CB 4.11Å; L218-H393 HydrophobicContact CD2-CB 4.28Å; L218-H393 HydrophobicContact CG-CB 4.47Å; H366-H393 AromaticContact CD2-CE1 3.66Å; H366-H393 AromaticContact NE2-CE1 3.04Å; H366-H393 PolarHBondContact NE2-CE1 3.23Å; H366-H393 AromaticContact NE2-ND1 3.98Å; H366-H393 AromaticContact NE2-NE2 3.39Å; H366-H393 PolarHBondContact NE2-NE2 3.02Å; H370-H393 AromaticContact CE1-NE2 3.74Å; H370-H393 AromaticContact NE2-NE2 3.28Å; H370-H393 PolarHBondContact NE2-NE2 3.11Å; F389-H393 AromaticContact CD1-CD2 3.6Å; F389-H393 AromaticContact CD2-CD2 3.71Å; F389-H393 AromaticContact CD2-NE2 3.74Å; F389-H393 HydrophobicContact CE1-CB 4.25Å; F389-H393 AromaticContact CE1-CD2 3.28Å; F389-H393 WeakPolarHBondContact CE1-CD2 3.31Å; F389-H393 AromaticContact CE1-CG 3.75Å; F389-H393 AromaticContact CE1-NE2 3.75Å; F389-H393 AromaticContact CE2-CD2 3.48Å; F389-H393 VanDerWaalsContact CE2-CD2 3.48Å; F389-H393 WeakPolarHBondContact CE2-CD2 3.43Å; F389-H393 AromaticContact CE2-NE2 3.16Å; F389-H393 WeakPolarHBondContact CE2-NE2 3.3Å; F389-H393 AromaticContact CG-CD2 3.78Å; F389-H393 AromaticContact CZ-CD2 3.25Å; F389-H393 WeakPolarHBondContact CZ-CD2 3.17Å; F389-H393 AromaticContact CZ-CE1 3.79Å; F389-H393 AromaticContact CZ-CG 3.91Å; F389-H393 AromaticContact CZ-NE2 3.17Å; F389-H393 WeakPolarHBondContact CZ-NE2 3.4Å; F389-H393 PolarHBondContact O-CD2 3.11Å; F389-H393 PolarHBondContact O-N 3.2Å; H393-F395 VanDerWaalsContact C-N 3.25Å; H393-F395 PolarHBondContact O-N 2.99Å; H393-I396 PolarHBondContact O-N 2.83Å; H393-D397 WeakPolarHBondContact O-CB 3.3Å; H393-D397 PolarHBondContact O-N 2.84Å
394A98.9Very high98.7Very high0 Ų04.4 Ų4.40%02%0.019CC..Hα-helixtrans-62.1-34.9170.400000111.7L218 I236 P237 L390 H392 S398 Y452L218-A394 HydrophobicContact CD1-CB 4.43Å; I236-A394 HydrophobicContact CG2-CB 4.21Å; P237-A394 WeakPolarHBondContact O-CB 3.34Å; L390-A394 WeakPolarHBondContact O-CB 3.13Å; L390-A394 PolarHBondContact O-N 2.83Å; H392-A394 VanDerWaalsContact C-N 3.3Å; H392-A394 PolarHBondContact O-N 2.71Å; A394-S398 PolarHBondContact O-N 3.13Å; A394-Y452 WeakPolarHBondContact O-CE1 3.36Å; A394-Y452 PolarHBondContact O-OH 3.45Å
395F98.9Very high98.6Very high0 Ų07.8 Ų7.80%03%0.031CC..Hα-helixtrans-73.6-39.8174.4-169-115.7000112.6Y238 W239 D240 W241 R242 L391 H392 H393 D397 S398 I399 Y454Y238-F395 AromaticContact CD2-CD2 3.57Å; Y238-F395 HydrophobicContact CD2-CD2 3.57Å; Y238-F395 HydrophobicContact CD2-CE2 4.26Å; Y238-F395 HydrophobicContact CD2-CG 4.47Å; Y238-F395 HydrophobicContact CE2-CD2 4.15Å; Y238-F395 HydrophobicContact CE2-CE2 4.42Å; Y238-F395 HydrophobicContact CG-CD2 4.33Å; W239-F395 WeakPolarHBondContact O-CB 3.38Å; W239-F395 WeakPolarHBondContact O-CG 3.27Å; D240-F395 HydrophobicContact CB-CD2 4.26Å; D240-F395 HydrophobicContact CB-CE2 3.81Å; D240-F395 HydrophobicContact CB-CZ 4.17Å; D240-F395 WeakPolarHBondContact OD1-CZ 3.45Å; W241-F395 AromaticContact CD1-CD1 3.86Å; W241-F395 HydrophobicContact CD2-CD1 4.06Å; W241-F395 HydrophobicContact CD2-CE1 4.13Å; W241-F395 AromaticContact CE2-CD1 3.47Å; W241-F395 VanDerWaalsContact CE2-CD1 3.47Å; W241-F395 AromaticContact CE2-CE1 3.87Å; W241-F395 HydrophobicContact CE3-CE1 4.43Å; W241-F395 HydrophobicContact CG-CD1 4.32Å; W241-F395 HydrophobicContact CH2-CD1 4.47Å; W241-F395 HydrophobicContact CH2-CE1 4.26Å; W241-F395 AromaticContact CZ2-CD1 3.76Å; W241-F395 HydrophobicContact CZ2-CD1 3.76Å; W241-F395 AromaticContact CZ2-CE1 3.99Å; W241-F395 HydrophobicContact CZ2-CE1 3.99Å; W241-F395 HydrophobicContact CZ3-CE1 4.42Å; W241-F395 AromaticContact NE1-CD1 3.35Å; R242-F395 HydrophobicContact CG-CE1 3.88Å; R242-F395 HydrophobicContact CG-CZ 3.79Å; L391-F395 PolarHBondContact O-N 3.29Å; H392-F395 WeakPolarHBondContact O-CA 3.42Å; H392-F395 WeakPolarHBondContact O-CB 3.45Å; H392-F395 PolarHBondContact O-N 3.47Å; H393-F395 VanDerWaalsContact C-N 3.25Å; H393-F395 PolarHBondContact O-N 2.99Å; F395-D397 VanDerWaalsContact C-N 3.34Å; F395-D397 PolarHBondContact O-N 3.33Å; F395-S398 WeakPolarHBondContact CD2-OG 3.36Å; F395-S398 WeakPolarHBondContact O-CB 3.38Å; F395-S398 PolarHBondContact O-N 2.95Å; F395-S398 VanDerWaalsContact O-N 3.09Å; F395-S398 PolarHBondContact O-OG 3.48Å; F395-I399 HydrophobicContact CD1-CD1 4Å; F395-I399 HydrophobicContact CE1-CD1 3.78Å; F395-I399 HydrophobicContact CE1-CG1 4.36Å; F395-I399 HydrophobicContact CZ-CD1 4.38Å; F395-I399 PolarHBondContact O-N 3.11Å; F395-I399 VanDerWaalsContact O-N 3.11Å; F395-Y454 HydrophobicContact CE2-CE1 4.47Å
396I98.9Very high98.5Very high3 Ų311.6 Ų11.62%0.0156%0.055CC..Hα-helixtrans-58.1-45.8173.1-65-58.6000111.4F210 L211 W241 L347 H366 H392 H393 S398 I399 F400F210-I396 HydrophobicContact CE1-CG2 4.1Å; F210-I396 HydrophobicContact CZ-CG2 4.12Å; L211-I396 HydrophobicContact CD2-CG2 3.66Å; W241-I396 HydrophobicContact CZ2-CD1 3.82Å; L347-I396 HydrophobicContact CD1-CD1 4.04Å; L347-I396 HydrophobicContact CD2-CG2 4.3Å; L347-I396 HydrophobicContact CG-CG2 4.37Å; H366-I396 HydrophobicContact CB-CD1 3.68Å; H366-I396 HydrophobicContact CB-CG1 4.12Å; H392-I396 PolarHBondContact O-N 2.91Å; H393-I396 PolarHBondContact O-N 2.83Å; I396-S398 PolarHBondContact O-N 3.33Å; I396-I399 HydrophobicContact CD1-CD1 4.48Å; I396-I399 WeakPolarHBondContact O-CB 3.25Å; I396-I399 PolarHBondContact O-N 3.16Å; I396-F400 PolarHBondContact O-N 3.3Å
397D98.9Very high98.4Very high6 Ų614.3 Ų14.33%0.0327%0.067CC..Hα-helixtrans-60.6-33.7175.5-179.159.1000112.6R121 R215 L218 H393 F395 I399 F400 E401 N445 Y450 Y452R121-D397 IonicContact NH1-OD2 3.42Å; R215-D397 IonicContact CZ-OD1 2.79Å; R215-D397 IonicContact NE-OD1 3.1Å; R215-D397 PolarHBondContact NE-OD1 2.91Å; R215-D397 IonicContact NH2-OD1 3.77Å; R215-D397 PolarHBondContact NH2-OD1 3.17Å; L218-D397 HydrophobicContact CD1-CB 4.24Å; H393-D397 WeakPolarHBondContact O-CB 3.3Å; H393-D397 PolarHBondContact O-N 2.84Å; F395-D397 VanDerWaalsContact C-N 3.34Å; F395-D397 PolarHBondContact O-N 3.33Å; D397-I399 VanDerWaalsContact C-N 3.35Å; D397-F400 WeakPolarHBondContact O-CB 3.44Å; D397-F400 PolarHBondContact O-N 3.48Å; D397-E401 PolarHBondContact O-N 3.19Å; D397-N445 PolarHBondContact OD2-ND2 3.38Å; D397-Y450 WeakPolarHBondContact OD2-CE2 3.45Å; D397-Y450 PolarHBondContact OD2-OH 3.45Å; D397-Y452 WeakPolarHBondContact CB-OH 3.31Å; D397-Y452 WeakPolarHBondContact OD2-CE2 3.29Å; D397-Y452 PolarHBondContact OD2-OH 2.91Å
398S98.8Very high98.3Very high0 Ų022 Ų220%010%0.103CC..Hα-helixtrans-67.6-34.3174.686.60000112.9A394 F395 I396 E401 R402 Y452 Y454A394-S398 PolarHBondContact O-N 3.13Å; F395-S398 WeakPolarHBondContact CD2-OG 3.36Å; F395-S398 WeakPolarHBondContact O-CB 3.38Å; F395-S398 PolarHBondContact O-N 2.95Å; F395-S398 VanDerWaalsContact O-N 3.09Å; F395-S398 PolarHBondContact O-OG 3.48Å; I396-S398 PolarHBondContact O-N 3.33Å; S398-E401 PolarHBondContact O-N 2.86Å; S398-R402 PolarHBondContact O-N 3.27Å; S398-Y452 VanDerWaalsContact CA-CE2 3.45Å; S398-Y452 VanDerWaalsContact CB-CD2 3.48Å; S398-Y454 WeakPolarHBondContact CB-OH 3.4Å; S398-Y454 WeakPolarHBondContact OG-CE1 3.44Å; S398-Y454 PolarHBondContact OG-OH 3.36Å
399I98.9Very high98.1Very high0 Ų023.6 Ų23.60%011%0.113CC..Hα-helixtrans-70.7-38.9175.3-62167.6000109.7W241 V321 V325 L347 F395 I396 D397 R402 W403W241-I399 HydrophobicContact CH2-CD1 4.42Å; W241-I399 HydrophobicContact CZ2-CD1 4.41Å; V321-I399 HydrophobicContact CG1-CD1 4.01Å; V321-I399 HydrophobicContact CG1-CG1 3.99Å; V321-I399 HydrophobicContact CG1-CG2 4.03Å; V321-I399 HydrophobicContact CG2-CD1 3.98Å; V325-I399 HydrophobicContact CG2-CG2 3.65Å; L347-I399 HydrophobicContact CD1-CB 4.16Å; L347-I399 HydrophobicContact CD1-CD1 3.96Å; L347-I399 HydrophobicContact CD1-CG2 3.77Å; L347-I399 HydrophobicContact CD2-CB 4.17Å; L347-I399 HydrophobicContact CD2-CG2 3.89Å; F395-I399 HydrophobicContact CD1-CD1 4Å; F395-I399 HydrophobicContact CE1-CD1 3.78Å; F395-I399 HydrophobicContact CE1-CG1 4.36Å; F395-I399 HydrophobicContact CZ-CD1 4.38Å; F395-I399 PolarHBondContact O-N 3.11Å; F395-I399 VanDerWaalsContact O-N 3.11Å; I396-I399 HydrophobicContact CD1-CD1 4.48Å; I396-I399 WeakPolarHBondContact O-CB 3.25Å; I396-I399 PolarHBondContact O-N 3.16Å; D397-I399 VanDerWaalsContact C-N 3.35Å; I399-R402 WeakPolarHBondContact O-CB 3.37Å; I399-R402 PolarHBondContact O-N 2.8Å; I399-W403 PolarHBondContact O-N 3.27Å
400F98.8Very high97.9Very high0 Ų029.5 Ų29.50%015%0.145CC..Hα-helixtrans-59.7-45.5172.5179.1-149000111.9L211 R215 Y330 F343 I396 D397 R402 W403 L404 F442L211-F400 HydrophobicContact CB-CB 4.39Å; L211-F400 HydrophobicContact CB-CD1 3.55Å; L211-F400 HydrophobicContact CB-CD2 4.34Å; L211-F400 HydrophobicContact CB-CE1 3.84Å; L211-F400 HydrophobicContact CB-CG 3.85Å; L211-F400 HydrophobicContact CB-CZ 4.36Å; L211-F400 HydrophobicContact CD1-CB 4.07Å; L211-F400 HydrophobicContact CD1-CD1 4.41Å; L211-F400 HydrophobicContact CD1-CD2 3.78Å; L211-F400 HydrophobicContact CD1-CE2 4.34Å; L211-F400 HydrophobicContact CD1-CG 3.84Å; L211-F400 HydrophobicContact CD2-CB 4.26Å; L211-F400 HydrophobicContact CG-CB 4.48Å; L211-F400 HydrophobicContact CG-CD1 4.46Å; L211-F400 HydrophobicContact CG-CG 4.3Å; R215-F400 VanDerWaalsContact CZ-CE1 3.4Å; Y330-F400 HydrophobicContact CE2-CE2 4.09Å; F343-F400 AromaticContact CE1-CD2 3.91Å; F343-F400 HydrophobicContact CE1-CD2 3.91Å; I396-F400 PolarHBondContact O-N 3.3Å; D397-F400 WeakPolarHBondContact O-CB 3.44Å; D397-F400 PolarHBondContact O-N 3.48Å; F400-R402 VanDerWaalsContact C-N 3.32Å; F400-R402 PolarHBondContact O-N 3.03Å; F400-W403 HydrophobicContact CD2-CE3 4.23Å; F400-W403 HydrophobicContact CE2-CE3 4.07Å; F400-W403 HydrophobicContact CE2-CZ3 4.32Å; F400-W403 WeakPolarHBondContact O-CB 3.17Å; F400-W403 PolarHBondContact O-N 2.81Å; F400-W403 VanDerWaalsContact O-N 3.16Å; F400-L404 HydrophobicContact CD1-CD1 4.49Å; F400-L404 HydrophobicContact CD2-CD1 4.12Å; F400-L404 HydrophobicContact CD2-CG 3.97Å; F400-L404 HydrophobicContact CE1-CD1 4.13Å; F400-L404 HydrophobicContact CE2-CD1 3.75Å; F400-L404 HydrophobicContact CE2-CD2 3.77Å; F400-L404 HydrophobicContact CE2-CG 3.59Å; F400-L404 HydrophobicContact CG-CD1 4.47Å; F400-L404 HydrophobicContact CZ-CD1 3.73Å; F400-L404 HydrophobicContact CZ-CD2 4.13Å; F400-L404 HydrophobicContact CZ-CG 4.07Å; F400-L404 WeakPolarHBondContact O-CG 3.33Å; F400-L404 PolarHBondContact O-N 2.94Å; F400-F442 HydrophobicContact CE2-CD2 4.09Å; F400-F442 AromaticContact CE2-CE2 3.77Å; F400-F442 HydrophobicContact CE2-CE2 3.77Å; F400-F442 AromaticContact CZ-CD2 3.61Å; F400-F442 HydrophobicContact CZ-CD2 3.61Å; F400-F442 AromaticContact CZ-CE2 3.81Å; F400-F442 HydrophobicContact CZ-CE2 3.81Å
401E98.5Very high97.6Very high0 Ų034.2 Ų34.20%016%0.162CC..Hα-helixtrans-59.7-41.5173.9178.457.5-160.400112.4D397 S398 W403 L404 R405 S444 N445 L455D397-E401 PolarHBondContact O-N 3.19Å; S398-E401 PolarHBondContact O-N 2.86Å; E401-W403 VanDerWaalsContact C-N 3.31Å; E401-W403 PolarHBondContact O-N 2.75Å; E401-L404 PolarHBondContact O-N 3.24Å; E401-R405 WeakPolarHBondContact O-CG 3.33Å; E401-R405 PolarHBondContact O-N 3.42Å; E401-R405 IonicContact OE1-CZ 3.1Å; E401-R405 VanDerWaalsContact OE1-CZ 3.26Å; E401-R405 IonicContact OE1-NE 2.61Å; E401-R405 PolarHBondContact OE1-NE 3.34Å; E401-R405 IonicContact OE1-NH2 3.16Å; E401-R405 PolarHBondContact OE1-NH2 2.85Å; E401-S444 PolarHBondContact OE1-OG 3.24Å; E401-S444 VanDerWaalsContact OE2-CA 3.26Å; E401-S444 WeakPolarHBondContact OE2-CA 3.17Å; E401-S444 PolarHBondContact OE2-OG 3.11Å; E401-N445 HydrophobicContact CG-CB 4.35Å; E401-N445 PolarHBondContact OE2-N 3.12Å; E401-N445 PolarHBondContact OE2-OD1 2.92Å; E401-L455 HydrophobicContact CB-CD1 4.18Å; E401-L455 HydrophobicContact CG-CD1 3.9Å
402R98.3Very high97.4Very high65 Ų6538.9 Ų38.925%0.24520%0.195CC..Hα-helixtrans-60.9-40.8175.2-172.8-176.9166.4-159.5-1.2111.7D322 V325 S398 I399 F400 R405 T406 L455D322-R402 IonicContact OD1-CZ 3.76Å; D322-R402 IonicContact OD1-NH1 3.82Å; D322-R402 PolarHBondContact OD1-NH1 3.28Å; D322-R402 IonicContact OD1-NH2 4Å; D322-R402 PolarHBondContact OD1-NH2 3.25Å; V325-R402 HydrophobicContact CG1-CG 4.03Å; V325-R402 HydrophobicContact CG2-CG 4.41Å; S398-R402 PolarHBondContact O-N 3.27Å; I399-R402 WeakPolarHBondContact O-CB 3.37Å; I399-R402 PolarHBondContact O-N 2.8Å; F400-R402 VanDerWaalsContact C-N 3.32Å; F400-R402 PolarHBondContact O-N 3.03Å; R402-R405 PolarHBondContact O-N 3.17Å; R402-T406 WeakPolarHBondContact O-CB 3.49Å; R402-T406 PolarHBondContact O-N 2.91Å; R402-T406 VanDerWaalsContact O-N 3.08Å; R402-T406 PolarHBondContact O-OG1 2.85Å; R402-L455 HydrophobicContact CB-CD2 4.4Å; R402-L455 HydrophobicContact CG-CD2 4.48Å
403W98.6Very high97.2Very high0 Ų041.2 Ų41.20%021%0.211CC..Hα-helixtrans-65.5-44.4176179.791.8000112.2L327 P328 Y330 F343 I399 F400 E401 R405 T406 H407 P409 F442L327-W403 PolarHBondContact O-NE1 2.75Å; P328-W403 WeakPolarHBondContact O-CZ2 3.35Å; Y330-W403 HydrophobicContact CD2-CH2 4.02Å; Y330-W403 AromaticContact CD2-CZ3 3.99Å; Y330-W403 HydrophobicContact CD2-CZ3 3.99Å; Y330-W403 HydrophobicContact CG-CH2 4.3Å; F343-W403 HydrophobicContact CD1-CB 4.36Å; F343-W403 AromaticContact CD1-CD1 3.76Å; F343-W403 AromaticContact CD1-CD2 3.55Å; F343-W403 HydrophobicContact CD1-CD2 3.55Å; F343-W403 AromaticContact CD1-CE2 3.7Å; F343-W403 HydrophobicContact CD1-CE3 4.08Å; F343-W403 AromaticContact CD1-CG 3.65Å; F343-W403 HydrophobicContact CD1-CG 3.65Å; F343-W403 HydrophobicContact CD1-CZ2 4.4Å; F343-W403 AromaticContact CD1-NE1 3.75Å; F343-W403 HydrophobicContact CD2-CB 4.31Å; F343-W403 AromaticContact CD2-CD1 3.32Å; F343-W403 HydrophobicContact CD2-CD2 4.49Å; F343-W403 AromaticContact CD2-CG 3.81Å; F343-W403 HydrophobicContact CD2-CG 3.81Å; F343-W403 AromaticContact CD2-NE1 3.78Å; F343-W403 HydrophobicContact CE1-CB 3.72Å; F343-W403 AromaticContact CE1-CD1 3.99Å; F343-W403 AromaticContact CE1-CD2 3.65Å; F343-W403 HydrophobicContact CE1-CD2 3.65Å; F343-W403 AromaticContact CE1-CE3 3.99Å; F343-W403 HydrophobicContact CE1-CE3 3.99Å; F343-W403 AromaticContact CE1-CG 3.5Å; F343-W403 HydrophobicContact CE1-CG 3.5Å; F343-W403 HydrophobicContact CE2-CB 3.66Å; F343-W403 AromaticContact CE2-CD1 3.57Å; F343-W403 AromaticContact CE2-CG 3.66Å; F343-W403 HydrophobicContact CE2-CG 3.66Å; F343-W403 AromaticContact CG-CD1 3.4Å; F343-W403 VanDerWaalsContact CG-CD1 3.4Å; F343-W403 AromaticContact CG-CD2 3.99Å; F343-W403 HydrophobicContact CG-CD2 3.99Å; F343-W403 AromaticContact CG-CE2 3.82Å; F343-W403 AromaticContact CG-CG 3.79Å; F343-W403 HydrophobicContact CG-CG 3.79Å; F343-W403 AromaticContact CG-NE1 3.39Å; F343-W403 HydrophobicContact CZ-CB 3.31Å; F343-W403 AromaticContact CZ-CD1 3.89Å; F343-W403 HydrophobicContact CZ-CD2 4.16Å; F343-W403 AromaticContact CZ-CG 3.5Å; F343-W403 HydrophobicContact CZ-CG 3.5Å; F343-W403 VanDerWaalsContact CZ-CG 3.5Å; I399-W403 PolarHBondContact O-N 3.27Å; F400-W403 HydrophobicContact CD2-CE3 4.23Å; F400-W403 HydrophobicContact CE2-CE3 4.07Å; F400-W403 HydrophobicContact CE2-CZ3 4.32Å; F400-W403 WeakPolarHBondContact O-CB 3.17Å; F400-W403 PolarHBondContact O-N 2.81Å; F400-W403 VanDerWaalsContact O-N 3.16Å; E401-W403 VanDerWaalsContact C-N 3.31Å; E401-W403 PolarHBondContact O-N 2.75Å; W403-R405 VanDerWaalsContact C-N 3.3Å; W403-R405 PolarHBondContact O-N 3.44Å; W403-T406 PolarHBondContact O-N 3.49Å; W403-T406 VanDerWaalsContact O-N 3.12Å; W403-H407 AromaticContact CD1-CE1 3.52Å; W403-H407 AromaticContact CD1-ND1 3.2Å; W403-H407 AromaticContact CD2-ND1 3.93Å; W403-H407 AromaticContact CE2-ND1 3.49Å; W403-H407 AromaticContact CG-ND1 3.75Å; W403-H407 HydrophobicContact CZ2-CB 4.4Å; W403-H407 AromaticContact NE1-CE1 3.37Å; W403-H407 PolarHBondContact NE1-CE1 2.82Å; W403-H407 AromaticContact NE1-ND1 3.03Å; W403-H407 PolarHBondContact NE1-ND1 2.88Å; W403-H407 PolarHBondContact O-N 2.86Å; W403-H407 PolarHBondContact O-ND1 3.27Å; W403-P409 HydrophobicContact CH2-CB 3.86Å; W403-P409 HydrophobicContact CH2-CG 3.69Å; W403-P409 HydrophobicContact CZ3-CB 4.3Å; W403-P409 HydrophobicContact CZ3-CG 3.6Å; W403-F442 AromaticContact CH2-CZ 3.87Å; W403-F442 HydrophobicContact CH2-CZ 3.87Å; W403-F442 AromaticContact CZ3-CE2 3.95Å; W403-F442 HydrophobicContact CZ3-CE2 3.95Å; W403-F442 AromaticContact CZ3-CZ 3.57Å; W403-F442 HydrophobicContact CZ3-CZ 3.57Å
404L98.1Very high97.2Very high14 Ų1441.2 Ų41.27%0.07321%0.211CC..Hα-helixtrans-57.8-40.9175.9-72.6169.6000112.1F400 E401 Q408 P409 F442F400-L404 HydrophobicContact CD1-CD1 4.49Å; F400-L404 HydrophobicContact CD2-CD1 4.12Å; F400-L404 HydrophobicContact CD2-CG 3.97Å; F400-L404 HydrophobicContact CE1-CD1 4.13Å; F400-L404 HydrophobicContact CE2-CD1 3.75Å; F400-L404 HydrophobicContact CE2-CD2 3.77Å; F400-L404 HydrophobicContact CE2-CG 3.59Å; F400-L404 HydrophobicContact CG-CD1 4.47Å; F400-L404 HydrophobicContact CZ-CD1 3.73Å; F400-L404 HydrophobicContact CZ-CD2 4.13Å; F400-L404 HydrophobicContact CZ-CG 4.07Å; F400-L404 WeakPolarHBondContact O-CG 3.33Å; F400-L404 PolarHBondContact O-N 2.94Å; E401-L404 PolarHBondContact O-N 3.24Å; L404-Q408 WeakPolarHBondContact O-CA 3.27Å; L404-Q408 PolarHBondContact O-N 2.85Å; L404-P409 HydrophobicContact CD2-CG 3.94Å; L404-F442 HydrophobicContact CD2-CE2 4.33Å; L404-F442 HydrophobicContact CD2-CZ 4.31Å
405R95.9Very high97.1Very high71 Ų7142 Ų4227%0.26822%0.216SC..Hα-helixtrans-68-37.5176.1-70.7177.9-166.7-158.2-0.4113.4E401 R402 W403 E451 L455E401-R405 WeakPolarHBondContact O-CG 3.33Å; E401-R405 PolarHBondContact O-N 3.42Å; E401-R405 IonicContact OE1-CZ 3.1Å; E401-R405 VanDerWaalsContact OE1-CZ 3.26Å; E401-R405 IonicContact OE1-NE 2.61Å; E401-R405 PolarHBondContact OE1-NE 3.34Å; E401-R405 IonicContact OE1-NH2 3.16Å; E401-R405 PolarHBondContact OE1-NH2 2.85Å; R402-R405 PolarHBondContact O-N 3.17Å; W403-R405 VanDerWaalsContact C-N 3.3Å; W403-R405 PolarHBondContact O-N 3.44Å; R405-E451 IonicContact CZ-OE1 2.72Å; R405-E451 IonicContact CZ-OE2 2.75Å; R405-E451 IonicContact NH1-OE1 3.26Å; R405-E451 IonicContact NH1-OE2 3.6Å; R405-E451 PolarHBondContact NH1-OE2 3.2Å; R405-E451 IonicContact NH2-OE1 2.63Å; R405-E451 PolarHBondContact NH2-OE1 2.82Å; R405-E451 IonicContact NH2-OE2 3.13Å; R405-E451 PolarHBondContact NH2-OE2 3.04Å; R405-L455 PolarHBondContact NH1-O 3.01Å
406T96.1Very high97Very high82 Ų8248 Ų4850%0.50324%0.244SC..Hα-helixtrans-70.4-45.2-176.2-59.10000110.6R402 W403R402-T406 WeakPolarHBondContact O-CB 3.49Å; R402-T406 PolarHBondContact O-N 2.91Å; R402-T406 VanDerWaalsContact O-N 3.08Å; R402-T406 PolarHBondContact O-OG1 2.85Å; W403-T406 PolarHBondContact O-N 3.49Å; W403-T406 VanDerWaalsContact O-N 3.12Å
407H96.8Very high96.9Very high57 Ų5748.7 Ų48.726%0.26425%0.251SS..Hα-helixtrans-100.1-23-171.8-66.7111.4000114.6V325 L327 P328 W403 P409V325-H407 PolarHBondContact O-CE1 3.16Å; L327-H407 PolarHBondContact O-CE1 3.31Å; P328-H407 WeakPolarHBondContact CA-NE2 3.46Å; W403-H407 AromaticContact CD1-CE1 3.52Å; W403-H407 AromaticContact CD1-ND1 3.2Å; W403-H407 AromaticContact CD2-ND1 3.93Å; W403-H407 AromaticContact CE2-ND1 3.49Å; W403-H407 AromaticContact CG-ND1 3.75Å; W403-H407 HydrophobicContact CZ2-CB 4.4Å; W403-H407 AromaticContact NE1-CE1 3.37Å; W403-H407 PolarHBondContact NE1-CE1 2.82Å; W403-H407 AromaticContact NE1-ND1 3.03Å; W403-H407 PolarHBondContact NE1-ND1 2.88Å; W403-H407 PolarHBondContact O-N 2.86Å; W403-H407 PolarHBondContact O-ND1 3.27Å; H407-P409 VanDerWaalsContact C-N 3.28Å
408Q96Very high96.8Very high161 Ų16152.8 Ų52.875%0.75227%0.272SS*.  trans44.752.8-175-58.3-179.21.400111.8L404L404-Q408 WeakPolarHBondContact O-CA 3.27Å; L404-Q408 PolarHBondContact O-N 2.85Å
409P96.1Very high96.8Very high34 Ų3452.8 Ų52.822%0.22127%0.272CS..  trans-61.7152.4-171.931.6-40.3000110.8W403 L404 H407 F442W403-P409 HydrophobicContact CH2-CB 3.86Å; W403-P409 HydrophobicContact CH2-CG 3.69Å; W403-P409 HydrophobicContact CZ3-CB 4.3Å; W403-P409 HydrophobicContact CZ3-CG 3.6Å; L404-P409 HydrophobicContact CD2-CG 3.94Å; H407-P409 VanDerWaalsContact C-N 3.28Å; P409-F442 HydrophobicContact CB-CE1 4.25Å; P409-F442 HydrophobicContact CB-CZ 4.46Å; P409-F442 HydrophobicContact CG-CE1 3.83Å; P409-F442 HydrophobicContact CG-CZ 3.97Å
410L94Very high96.8Very high125 Ų12553.5 Ų53.565%0.65428%0.277SS*.  trans-65.4150.9169.8-63.7176.3000109.5S412 S413L410-S412 PolarHBondContact O-N 3.48Å; L410-S412 VanDerWaalsContact O-N 3.13Å; L410-S413 WeakPolarHBondContact O-CB 3.42Å; L410-S413 PolarHBondContact O-N 2.71Å; L410-S413 PolarHBondContact O-OG 3.29Å
411R93.4Very high96.7Very high98 Ų9854 Ų5437%0.3728%0.28SS..G310 helixtrans-56.3-31.8175.4179.458.7-172.969.712.6112.3S413 Y414 D425 G439R411-S413 PolarHBondContact O-N 3.31Å; R411-Y414 PolarHBondContact O-N 2.95Å; R411-D425 IonicContact CZ-OD1 3.42Å; R411-D425 IonicContact CZ-OD2 2.58Å; R411-D425 IonicContact NH1-OD1 3.68Å; R411-D425 PolarHBondContact NH1-OD1 3.02Å; R411-D425 IonicContact NH1-OD2 3.46Å; R411-D425 IonicContact NH2-OD1 3Å; R411-D425 PolarHBondContact NH2-OD1 2.61Å; R411-D425 IonicContact NH2-OD2 2.78Å; R411-D425 PolarHBondContact NH2-OD2 2.77Å; R411-G439 VanDerWaalsContact CZ-C 3.41Å; R411-G439 VanDerWaalsContact CZ-CA 3.49Å; R411-G439 PolarHBondContact NE-O 2.96Å; R411-G439 PolarHBondContact NH2-O 2.81Å
412S93.5Very high96.7Very high98 Ų9854 Ų5469%0.68528%0.28SS*.G310 helixtrans-73-5176.458.10000114.7L410 Y414L410-S412 PolarHBondContact O-N 3.48Å; L410-S412 VanDerWaalsContact O-N 3.13Å; S412-Y414 PolarHBondContact O-N 2.58Å
413S94.9Very high96.7Very high49 Ų4951 Ų5134%0.34327%0.268SS..G310 helixtrans-72-18.2172.2-61.80000112.4L410 R411L410-S413 WeakPolarHBondContact O-CB 3.42Å; L410-S413 PolarHBondContact O-N 2.71Å; L410-S413 PolarHBondContact O-OG 3.29Å; R411-S413 PolarHBondContact O-N 3.31Å
414Y97.9Very high96.7Very high3 Ų351 Ų511%0.01227%0.269CS..SBendtrans-78135.4168.7-164.5-83.7000109.7A208 A209 P212 Y330 R411 S412 Q416 H423 D425 N438 F442A208-Y414 HydrophobicContact CB-CE1 4.45Å; A208-Y414 HydrophobicContact CB-CE2 4.16Å; A208-Y414 WeakPolarHBondContact O-CE2 3.4Å; A208-Y414 PolarHBondContact O-OH 3.13Å; A209-Y414 WeakPolarHBondContact CA-OH 3.43Å; A209-Y414 PolarHBondContact N-OH 2.71Å; P212-Y414 HydrophobicContact CG-CE2 3.84Å; Y330-Y414 HydrophobicContact CD1-CD2 4.17Å; Y330-Y414 AromaticContact CE1-CD2 3.6Å; Y330-Y414 HydrophobicContact CE1-CD2 3.6Å; Y330-Y414 AromaticContact CE1-CE2 3.63Å; Y330-Y414 HydrophobicContact CE1-CE2 3.63Å; R411-Y414 PolarHBondContact O-N 2.95Å; S412-Y414 PolarHBondContact O-N 2.58Å; Y414-Q416 PolarHBondContact O-N 2.73Å; Y414-H423 VanDerWaalsContact CE1-O 3.29Å; Y414-H423 WeakPolarHBondContact CE1-O 3.34Å; Y414-H423 PolarHBondContact OH-O 2.98Å; Y414-D425 HydrophobicContact CD1-CB 3.95Å; Y414-D425 WeakPolarHBondContact CD1-OD1 3.45Å; Y414-D425 HydrophobicContact CE1-CB 4.38Å; Y414-N438 HydrophobicContact CE1-CB 3.87Å; Y414-N438 WeakPolarHBondContact OH-CB 3.08Å; Y414-F442 HydrophobicContact CD2-CB 3.91Å; Y414-F442 HydrophobicContact CD2-CD1 4.43Å; Y414-F442 AromaticContact CD2-CD2 3.6Å; Y414-F442 HydrophobicContact CD2-CD2 3.6Å; Y414-F442 HydrophobicContact CD2-CE2 4.24Å; Y414-F442 AromaticContact CD2-CG 3.72Å; Y414-F442 HydrophobicContact CD2-CG 3.72Å; Y414-F442 HydrophobicContact CE2-CD2 4.38Å; Y414-F442 HydrophobicContact CG-CB 4.31Å; Y414-F442 HydrophobicContact CG-CG 4.24Å
415P97.3Very high96.7Very high16 Ų1652 Ų5210%0.10427%0.274CS..  trans-68.3121.2-171.225-33.9000113.1A208 M335 A419 D425A208-P415 HydrophobicContact CB-CG 3.34Å; M335-P415 HydrophobicContact SD-CB 3.4Å; M335-P415 WeakPolarHBondContact SD-CB 3.41Å; M335-P415 HydrophobicContact SD-CG 4.03Å; P415-A419 HydrophobicContact CB-CB 4.48Å; P415-A419 HydrophobicContact CG-CB 4.33Å; P415-D425 WeakPolarHBondContact O-CB 3.38Å; P415-D425 PolarHBondContact O-N 3.04Å
416Q97.3Very high96.8Very high125 Ų12549.1 Ų49.158%0.58427%0.267SS*.  trans-67.8-42.8178.1-178.1177.1-10.800112.7E64 Y414E64-Q416 HydrophobicContact CG-CG 4.38Å; E64-Q416 PolarHBondContact OE1-NE2 3Å; Y414-Q416 PolarHBondContact O-N 2.73Å
417A97.4Very high96.9Very high19 Ų1946.1 Ų46.116%0.15725%0.246CC..SBendtrans-148.6167.9-171.100000111.7E64 P65 A419 N424E64-A417 HydrophobicContact CB-CB 4.02Å; P65-A417 HydrophobicContact CG-CB 4.23Å; A417-A419 PolarHBondContact O-N 2.69Å; A417-A419 VanDerWaalsContact O-N 3.16Å; A417-N424 VanDerWaalsContact CA-OD1 3.28Å; A417-N424 WeakPolarHBondContact CA-OD1 3.47Å
418N97.3Very high96.9Very high91 Ų9144.9 Ų44.949%0.48724%0.239SC..SBendtrans63.36.1177-50.2-61.7000116P65 G67 M335 N424P65-N418 WeakPolarHBondContact CG-OD1 3.5Å; P65-N418 WeakPolarHBondContact O-CA 3.43Å; P65-N418 PolarHBondContact O-N 2.79Å; G67-N418 VanDerWaalsContact CA-O 3.24Å; G67-N418 WeakPolarHBondContact CA-O 3.31Å; G67-N418 PolarHBondContact N-O 3.21Å; M335-N418 HydrophobicContact CE-CB 4.32Å; N418-N424 PolarHBondContact N-OD1 3.46Å
419A97.9Very high97Very high0 Ų037.3 Ų37.30%020%0.204CC..SBendtrans-67.6155.2165.600000109.2G67 M335 P415 A417 H423 N424G67-A419 PolarHBondContact N-O 2.75Å; M335-A419 HydrophobicContact SD-CB 4.42Å; P415-A419 HydrophobicContact CB-CB 4.48Å; P415-A419 HydrophobicContact CG-CB 4.33Å; A417-A419 PolarHBondContact O-N 2.69Å; A417-A419 VanDerWaalsContact O-N 3.16Å; A419-H423 HydrophobicContact CB-CB 3.85Å; A419-N424 WeakPolarHBondContact CB-OD1 3.47Å; A419-N424 PolarHBondContact N-OD1 3.31Å
420P97.9Very high97.1Very high15 Ų1535.7 Ų35.710%0.09719%0.193CC..SBendtrans-37.5142.7164.9-3435.2000112.9Q69 S207 M335 D336 G422 H423Q69-P420 HydrophobicContact CG-CG 4.47Å; S207-P420 VanDerWaalsContact OG-CD 3.25Å; S207-P420 WeakPolarHBondContact OG-CD 3.46Å; S207-P420 WeakPolarHBondContact OG-CG 3.39Å; M335-P420 WeakPolarHBondContact O-CD 3.05Å; D336-P420 HydrophobicContact CB-CG 4.25Å; P420-G422 PolarHBondContact O-N 2.81Å; P420-H423 WeakPolarHBondContact O-CB 3.45Å; P420-H423 PolarHBondContact O-CD2 2.92Å; P420-H423 PolarHBondContact O-N 3.42Å
421I98.1Very high97.2Very high11 Ų1129.8 Ų29.86%0.05616%0.163CC..THydrogen-bonded Turntrans-50.1129.6-176.3-175170.8000110.5N66 Y70 E79 I201 F203 H423 Y427N66-I421 HydrophobicContact CB-CB 4.17Å; Y70-I421 HydrophobicContact CD1-CD1 3.79Å; Y70-I421 HydrophobicContact CD1-CG2 4.25Å; Y70-I421 HydrophobicContact CE1-CD1 4.11Å; Y70-I421 HydrophobicContact CG-CG2 4.01Å; E79-I421 HydrophobicContact CG-CD1 4.04Å; I201-I421 HydrophobicContact CD1-CG2 4.16Å; I201-I421 HydrophobicContact CG1-CG2 4.16Å; F203-I421 HydrophobicContact CE1-CD1 4.49Å; F203-I421 HydrophobicContact CE1-CG1 4Å; F203-I421 HydrophobicContact CE1-CG2 4.38Å; F203-I421 HydrophobicContact CZ-CD1 4.44Å; F203-I421 HydrophobicContact CZ-CG1 4.36Å; F203-I421 HydrophobicContact CZ-CG2 4.32Å; I421-H423 PolarHBondContact O-CD2 3.37Å; I421-Y427 HydrophobicContact CG1-CE2 4.08Å
422G97.9Very high97.4Very high0 Ų025.1 Ų25.10%015%0.145CC..THydrogen-bonded Turntrans96.9-17.7-175.500000115.7P420 N438P420-G422 PolarHBondContact O-N 2.81Å; G422-N438 PolarHBondContact O-ND2 3.06Å
423H98.6Very high97.4Very high1 Ų120.7 Ų20.71%0.00511%0.114CC..  trans-102.5-11-170.2-63.5-100000114.8D202 H205 S207 A208 A209 Y414 A419 P420 I421D202-H423 PolarHBondContact O-NE2 3.25Å; H205-H423 PolarHBondContact O-CE1 2.75Å; H205-H423 PolarHBondContact O-NE2 2.66Å; S207-H423 VanDerWaalsContact C-ND1 3.33Å; S207-H423 VanDerWaalsContact CB-CG 3.41Å; S207-H423 VanDerWaalsContact CB-ND1 3.3Å; S207-H423 WeakPolarHBondContact CB-ND1 3.1Å; S207-H423 PolarHBondContact O-ND1 2.88Å; S207-H423 WeakPolarHBondContact OG-CB 3.46Å; A208-H423 HydrophobicContact CB-CB 4.31Å; A209-H423 HydrophobicContact CB-CB 4.22Å; A209-H423 VanDerWaalsContact CB-ND1 3.31Å; A209-H423 WeakPolarHBondContact CB-ND1 3.01Å; A209-H423 PolarHBondContact N-ND1 2.74Å; Y414-H423 VanDerWaalsContact CE1-O 3.29Å; Y414-H423 WeakPolarHBondContact CE1-O 3.34Å; Y414-H423 PolarHBondContact OH-O 2.98Å; A419-H423 HydrophobicContact CB-CB 3.85Å; P420-H423 WeakPolarHBondContact O-CB 3.45Å; P420-H423 PolarHBondContact O-CD2 2.92Å; P420-H423 PolarHBondContact O-N 3.42Å; I421-H423 PolarHBondContact O-CD2 3.37Å
424N98.3Very high97.3Very high2 Ų219.3 Ų19.31%0.01110%0.103CC..SBendtrans-57.7152.6174.2-76-16.8000111.9P65 N66 A417 N418 A419 G426 Y427 N438P65-N424 PolarHBondContact O-ND2 3.16Å; N66-N424 PolarHBondContact OD1-ND2 3.02Å; A417-N424 VanDerWaalsContact CA-OD1 3.28Å; A417-N424 WeakPolarHBondContact CA-OD1 3.47Å; N418-N424 PolarHBondContact N-OD1 3.46Å; A419-N424 WeakPolarHBondContact CB-OD1 3.47Å; A419-N424 PolarHBondContact N-OD1 3.31Å; N424-G426 PolarHBondContact O-N 3.33Å; N424-Y427 VanDerWaalsContact O-CB 3.31Å; N424-Y427 WeakPolarHBondContact O-CB 3.17Å; N424-Y427 PolarHBondContact O-N 3.06Å; N424-N438 PolarHBondContact O-ND2 3.06Å
425D97.9Very high97.2Very high34 Ų3420.6 Ų20.618%0.18211%0.11CC..THydrogen-bonded Turntrans-46.9-54.4-179.2-171.376.3000114.4R411 Y414 P415 Y427 N438 G439R411-D425 IonicContact CZ-OD1 3.42Å; R411-D425 IonicContact CZ-OD2 2.58Å; R411-D425 IonicContact NH1-OD1 3.68Å; R411-D425 PolarHBondContact NH1-OD1 3.02Å; R411-D425 IonicContact NH1-OD2 3.46Å; R411-D425 IonicContact NH2-OD1 3Å; R411-D425 PolarHBondContact NH2-OD1 2.61Å; R411-D425 IonicContact NH2-OD2 2.78Å; R411-D425 PolarHBondContact NH2-OD2 2.77Å; Y414-D425 HydrophobicContact CD1-CB 3.95Å; Y414-D425 WeakPolarHBondContact CD1-OD1 3.45Å; Y414-D425 HydrophobicContact CE1-CB 4.38Å; P415-D425 WeakPolarHBondContact O-CB 3.38Å; P415-D425 PolarHBondContact O-N 3.04Å; D425-Y427 VanDerWaalsContact C-N 3.27Å; D425-Y427 PolarHBondContact O-N 3.09Å; D425-N438 PolarHBondContact O-N 3.48Å; D425-G439 PolarHBondContact O-N 3.42Å; D425-G439 VanDerWaalsContact OD1-CA 3.3Å; D425-G439 WeakPolarHBondContact OD1-CA 3.33Å
426G97.3Very high97.2Very high11 Ų1121.2 Ų21.211%0.11311%0.111CC..THydrogen-bonded Turntrans-82.61.9-176.400000114N424 R437N424-G426 PolarHBondContact O-N 3.33Å; G426-R437 PolarHBondContact O-NH1 3.41Å
427Y98.2Very high97.1Very high19 Ų1918 Ų188%0.0759%0.093CC..PPolyproline II helixtrans-74135179.6-145.5-71.4000109.9R78 R80 W81 F203 I421 N424 D425 I430 R437 N438R78-Y427 PolarHBondContact O-OH 3.39Å; R78-Y427 VanDerWaalsContact O-OH 3.07Å; R80-Y427 PolarHBondContact N-OH 2.93Å; W81-Y427 HydrophobicContact CB-CE1 4.34Å; F203-Y427 HydrophobicContact CE1-CE1 4.47Å; I421-Y427 HydrophobicContact CG1-CE2 4.08Å; N424-Y427 VanDerWaalsContact O-CB 3.31Å; N424-Y427 WeakPolarHBondContact O-CB 3.17Å; N424-Y427 PolarHBondContact O-N 3.06Å; D425-Y427 VanDerWaalsContact C-N 3.27Å; D425-Y427 PolarHBondContact O-N 3.09Å; Y427-I430 HydrophobicContact CD1-CD1 3.85Å; Y427-I430 HydrophobicContact CE1-CD1 3.51Å; Y427-I430 HydrophobicContact CE1-CG1 4.42Å; Y427-R437 WeakPolarHBondContact O-CA 3.05Å; Y427-N438 PolarHBondContact O-N 2.69Å; Y427-N438 VanDerWaalsContact O-N 3.11Å
428Y98.4Very high97.2Very high31 Ų3117 Ų1712%0.1229%0.086CC..BIsolated β-bridgetrans-77.7124.6173.7-70.7-62.6000110.3V59 L60 V61 W81 I430 L435 Y436 R437V59-Y428 HydrophobicContact CG1-CD2 4.33Å; V59-Y428 HydrophobicContact CG1-CE2 3.67Å; L60-Y428 VanDerWaalsContact O-CE2 3.27Å; L60-Y428 WeakPolarHBondContact O-CE2 3.5Å; L60-Y428 PolarHBondContact O-OH 3.4Å; V61-Y428 HydrophobicContact CG1-CD2 4.16Å; V61-Y428 HydrophobicContact CG1-CE2 4.21Å; W81-Y428 WeakPolarHBondContact O-CD2 3.1Å; Y428-I430 WeakPolarHBondContact O-CD1 3.48Å; Y428-I430 PolarHBondContact O-N 3.22Å; Y428-L435 HydrophobicContact CD1-CB 3.58Å; Y428-L435 HydrophobicContact CD1-CD1 4.4Å; Y428-L435 HydrophobicContact CD1-CG 4.4Å; Y428-L435 HydrophobicContact CD2-CD1 4.2Å; Y428-L435 HydrophobicContact CE1-CB 3.62Å; Y428-L435 HydrophobicContact CE1-CD1 4.16Å; Y428-L435 HydrophobicContact CE1-CG 4.46Å; Y428-L435 HydrophobicContact CE2-CD1 3.95Å; Y428-L435 HydrophobicContact CG-CB 4.15Å; Y428-L435 HydrophobicContact CG-CD1 4.39Å; Y428-L435 HydrophobicContact CG-CD2 4.3Å; Y428-Y436 CarbonylContact C-O 3.48Å; Y428-Y436 VanDerWaalsContact CA-O 3.24Å; Y428-Y436 WeakPolarHBondContact CA-O 3.35Å; Y428-R437 HydrophobicContact CD1-CG 3.52Å; Y428-R437 HydrophobicContact CE1-CG 3.54Å; Y428-R437 HydrophobicContact CG-CG 4.45Å; Y428-R437 VanDerWaalsContact CZ-CZ 3.44Å; Y428-R437 VanDerWaalsContact CZ-NH2 3.31Å; Y428-R437 PolarHBondContact OH-NH2 3.35Å
429M98.4Very high97.1Very high1 Ų112.7 Ų12.71%0.0056%0.062CC..PPolyproline II helixtrans-55.5118178.3-65.5174.4-17400111.6P212 V216 F432 Y436 N438 Y441P212-M429 HydrophobicContact CB-CE 3.77Å; P212-M429 WeakPolarHBondContact O-CE 3.17Å; V216-M429 HydrophobicContact CB-CE 4.39Å; V216-M429 HydrophobicContact CB-SD 3.71Å; V216-M429 HydrophobicContact CG1-SD 4.06Å; V216-M429 HydrophobicContact CG2-CE 3.72Å; V216-M429 HydrophobicContact CG2-SD 3.59Å; V216-M429 VanDerWaalsContact CG2-SD 3.59Å; M429-F432 HydrophobicContact CB-CD2 3.57Å; M429-F432 HydrophobicContact CB-CE2 4.02Å; M429-F432 PolarHBondContact O-N 2.86Å; M429-F432 VanDerWaalsContact O-N 3.12Å; M429-F432 HydrophobicContact SD-CD2 4.34Å; M429-F432 HydrophobicContact SD-CE2 4.3Å; M429-Y436 PolarHBondContact N-O 3.36Å; M429-N438 VanDerWaalsContact CG-OD1 3.23Å; M429-N438 WeakPolarHBondContact CG-OD1 3.11Å; M429-Y441 HydrophobicContact CE-CD2 3.78Å; M429-Y441 HydrophobicContact CE-CG 4.01Å
430I97.4Very high97Very high0 Ų016.5 Ų16.50%08%0.083CC..THydrogen-bonded Turntrans-75147.8178.9-59.180.4000109.6R78 W81 Y184 V185 F203 W213 Y427 Y428R78-I430 HydrophobicContact CB-CG1 4.34Å; R78-I430 HydrophobicContact CB-CG2 4.18Å; R78-I430 HydrophobicContact CG-CG2 3.84Å; W81-I430 HydrophobicContact CB-CD1 4.32Å; W81-I430 HydrophobicContact CB-CG1 3.7Å; W81-I430 HydrophobicContact CD2-CG1 4.39Å; W81-I430 HydrophobicContact CD2-CG2 4.4Å; W81-I430 HydrophobicContact CE3-CG2 4.33Å; W81-I430 HydrophobicContact CG-CB 4.49Å; W81-I430 HydrophobicContact CG-CG1 3.91Å; Y184-I430 HydrophobicContact CD1-CG2 3.94Å; Y184-I430 HydrophobicContact CE1-CG2 3.95Å; V185-I430 HydrophobicContact CG1-CB 4.05Å; V185-I430 HydrophobicContact CG1-CG2 4.09Å; V185-I430 WeakPolarHBondContact CG1-O 3.44Å; F203-I430 HydrophobicContact CB-CB 4.33Å; F203-I430 HydrophobicContact CB-CD1 3.94Å; F203-I430 HydrophobicContact CB-CG1 4.4Å; F203-I430 HydrophobicContact CD1-CD1 3.2Å; F203-I430 HydrophobicContact CD1-CG1 3.86Å; F203-I430 HydrophobicContact CE1-CD1 3.88Å; F203-I430 HydrophobicContact CE1-CG1 4.34Å; F203-I430 HydrophobicContact CG-CD1 3.83Å; F203-I430 HydrophobicContact CG-CG1 4.2Å; W213-I430 PolarHBondContact NE1-O 3.15Å; Y427-I430 HydrophobicContact CD1-CD1 3.85Å; Y427-I430 HydrophobicContact CE1-CD1 3.51Å; Y427-I430 HydrophobicContact CE1-CG1 4.42Å; Y428-I430 WeakPolarHBondContact O-CD1 3.48Å; Y428-I430 PolarHBondContact O-N 3.22Å
431P96.5Very high97Very high1 Ų116.4 Ų16.41%0.0068%0.081CC..THydrogen-bonded Turncis-98.444.4-21.637.4-24.7000109.7Q20 W81 W180 I181 Y184Q20-P431 HydrophobicContact CG-CG 4.43Å; Q20-P431 PolarHBondContact NE2-O 2.88Å; Q20-P431 VanDerWaalsContact NE2-O 3.16Å; W81-P431 HydrophobicContact CH2-CB 3.52Å; W81-P431 HydrophobicContact CZ2-CB 3.67Å; W81-P431 VanDerWaalsContact CZ2-O 3.26Å; W81-P431 WeakPolarHBondContact CZ2-O 3.22Å; W81-P431 HydrophobicContact CZ3-CB 4.04Å; W180-P431 HydrophobicContact CZ3-CG 4.07Å; I181-P431 HydrophobicContact CG1-CG 4.22Å; I181-P431 HydrophobicContact CG2-CG 4.38Å; Y184-P431 HydrophobicContact CD1-CB 3.62Å; Y184-P431 HydrophobicContact CD1-CG 3.71Å; Y184-P431 HydrophobicContact CE1-CB 3.86Å; Y184-P431 HydrophobicContact CE1-CG 4.44Å; Y184-P431 HydrophobicContact CG-CG 4.43Å
432F96.6Very high97Very high1 Ų116.3 Ų16.30%0.0048%0.08CC..  trans-70.8137-174.7-64-58.9000111.4W81 I181 W213 V216 F217 M429 P434 Y436W81-F432 PolarHBondContact NE1-O 2.8Å; I181-F432 HydrophobicContact CD1-CE1 4.44Å; I181-F432 HydrophobicContact CG2-CE1 4Å; I181-F432 HydrophobicContact CG2-CZ 4.33Å; W213-F432 HydrophobicContact CD2-CE2 4.28Å; W213-F432 AromaticContact CE2-CE2 3.76Å; W213-F432 AromaticContact CE2-CZ 3.96Å; W213-F432 HydrophobicContact CG-CE2 4.43Å; W213-F432 HydrophobicContact CH2-CZ 4.45Å; W213-F432 HydrophobicContact CZ2-CE2 4.16Å; W213-F432 AromaticContact CZ2-CZ 3.92Å; W213-F432 HydrophobicContact CZ2-CZ 3.92Å; W213-F432 AromaticContact NE1-CE2 3.62Å; V216-F432 HydrophobicContact CB-CE2 4.3Å; V216-F432 HydrophobicContact CG1-CD2 3.98Å; V216-F432 HydrophobicContact CG1-CE2 3.85Å; V216-F432 HydrophobicContact CG1-CG 4.48Å; V216-F432 HydrophobicContact CG1-CZ 4.24Å; F217-F432 HydrophobicContact CB-CZ 3.9Å; F217-F432 HydrophobicContact CD2-CE1 4.25Å; F217-F432 HydrophobicContact CD2-CZ 4.02Å; F217-F432 HydrophobicContact CG-CZ 4.49Å; M429-F432 HydrophobicContact CB-CD2 3.57Å; M429-F432 HydrophobicContact CB-CE2 4.02Å; M429-F432 PolarHBondContact O-N 2.86Å; M429-F432 VanDerWaalsContact O-N 3.12Å; M429-F432 HydrophobicContact SD-CD2 4.34Å; M429-F432 HydrophobicContact SD-CE2 4.3Å; F432-P434 CarbonylContact C-O 3.59Å; F432-Y436 HydrophobicContact CB-CD2 3.72Å; F432-Y436 HydrophobicContact CB-CE2 4.16Å; F432-Y436 HydrophobicContact CD2-CD2 4.22Å; F432-Y436 HydrophobicContact CG-CD2 4.08Å
433L93.8Very high96.8Very high5 Ų518.4 Ų18.43%0.0269%0.091CC..SBendtrans-134.8118.5163.9-78.3166.9000108.2F21 W81 F86 T89 Y150 L435F21-L433 HydrophobicContact CB-CD1 4.41Å; F21-L433 HydrophobicContact CD1-CD1 3.28Å; F21-L433 HydrophobicContact CE1-CD1 3.89Å; F21-L433 HydrophobicContact CG-CD1 4.33Å; W81-L433 HydrophobicContact CZ2-CD1 4.26Å; W81-L433 HydrophobicContact CZ2-CG 4.21Å; F86-L433 HydrophobicContact CD2-CD1 4.4Å; T89-L433 HydrophobicContact CG2-CD2 4.07Å; Y150-L433 WeakPolarHBondContact CE1-O 3.28Å; Y150-L433 VanDerWaalsContact CZ-O 3.32Å; Y150-L433 PolarHBondContact OH-O 3.26Å; L433-L435 HydrophobicContact CD2-CD2 3.63Å; L433-L435 HydrophobicContact CD2-CG 3.95Å
434P92.9Very high96.7Very high19 Ų1920.1 Ų20.112%0.12310%0.103CC..SBendcis-68.1165.310.732.6-38.1000113.4F432 Y436F432-P434 CarbonylContact C-O 3.59Å; P434-Y436 HydrophobicContact CG-CE1 4.39Å; P434-Y436 HydrophobicContact CG-CE2 4.27Å; P434-Y436 WeakPolarHBondContact CG-OH 3.18Å; P434-Y436 WeakPolarHBondContact O-CD2 3.44Å; P434-Y436 WeakPolarHBondContact O-CE2 3.04Å
435L95.8Very high96.5Very high30 Ų3020 Ų2016%0.15710%0.102CC..  trans-78.3135.3-172.6-62.3176.6000112.1V59 P82 Y428 L433V59-L435 HydrophobicContact CB-CD1 4.41Å; V59-L435 HydrophobicContact CG1-CD1 3.58Å; V59-L435 HydrophobicContact CG2-CD1 3.89Å; P82-L435 HydrophobicContact CB-CD2 4.3Å; P82-L435 HydrophobicContact CG-CD1 4.13Å; P82-L435 HydrophobicContact CG-CD2 3.82Å; Y428-L435 HydrophobicContact CD1-CB 3.58Å; Y428-L435 HydrophobicContact CD1-CD1 4.4Å; Y428-L435 HydrophobicContact CD1-CG 4.4Å; Y428-L435 HydrophobicContact CD2-CD1 4.2Å; Y428-L435 HydrophobicContact CE1-CB 3.62Å; Y428-L435 HydrophobicContact CE1-CD1 4.16Å; Y428-L435 HydrophobicContact CE1-CG 4.46Å; Y428-L435 HydrophobicContact CE2-CD1 3.95Å; Y428-L435 HydrophobicContact CG-CB 4.15Å; Y428-L435 HydrophobicContact CG-CD1 4.39Å; Y428-L435 HydrophobicContact CG-CD2 4.3Å; L433-L435 HydrophobicContact CD2-CD2 3.63Å; L433-L435 HydrophobicContact CD2-CG 3.95Å
436Y96.6Very high96.2Very high29 Ų2921.6 Ų21.611%0.11411%0.108CC..  trans-128.1131.4177.9-59.6-60.7000109.6F106 V216 Y428 M429 F432 P434 Y441F106-Y436 HydrophobicContact CE2-CE1 4.21Å; V216-Y436 HydrophobicContact CG1-CD2 3.49Å; V216-Y436 VanDerWaalsContact CG1-CD2 3.49Å; V216-Y436 HydrophobicContact CG1-CE2 3.88Å; V216-Y436 HydrophobicContact CG1-CG 3.97Å; Y428-Y436 CarbonylContact C-O 3.48Å; Y428-Y436 VanDerWaalsContact CA-O 3.24Å; Y428-Y436 WeakPolarHBondContact CA-O 3.35Å; M429-Y436 PolarHBondContact N-O 3.36Å; F432-Y436 HydrophobicContact CB-CD2 3.72Å; F432-Y436 HydrophobicContact CB-CE2 4.16Å; F432-Y436 HydrophobicContact CD2-CD2 4.22Å; F432-Y436 HydrophobicContact CG-CD2 4.08Å; P434-Y436 HydrophobicContact CG-CE1 4.39Å; P434-Y436 HydrophobicContact CG-CE2 4.27Å; P434-Y436 WeakPolarHBondContact CG-OH 3.18Å; P434-Y436 WeakPolarHBondContact O-CD2 3.44Å; P434-Y436 WeakPolarHBondContact O-CE2 3.04Å; Y436-Y441 AromaticContact CD1-CE2 3.64Å; Y436-Y441 HydrophobicContact CD1-CE2 3.64Å; Y436-Y441 AromaticContact CD1-CZ 3.56Å; Y436-Y441 WeakPolarHBondContact CD1-OH 3.32Å; Y436-Y441 WeakPolarHBondContact CE1-OH 3.46Å; Y436-Y441 AromaticContact CG-CE2 3.97Å; Y436-Y441 HydrophobicContact CG-CE2 3.97Å
437R97.1Very high96Very high57 Ų5724.8 Ų24.822%0.21513%0.125CC..BIsolated β-bridgetrans-92.8144175.9-62.3-177.1-172.2-90.94.5110.8L60 G426 Y427 Y428 G439 D440 Y441L60-R437 PolarHBondContact O-NH2 2.91Å; G426-R437 PolarHBondContact O-NH1 3.41Å; Y427-R437 WeakPolarHBondContact O-CA 3.05Å; Y428-R437 HydrophobicContact CD1-CG 3.52Å; Y428-R437 HydrophobicContact CE1-CG 3.54Å; Y428-R437 HydrophobicContact CG-CG 4.45Å; Y428-R437 VanDerWaalsContact CZ-CZ 3.44Å; Y428-R437 VanDerWaalsContact CZ-NH2 3.31Å; Y428-R437 PolarHBondContact OH-NH2 3.35Å; R437-G439 PolarHBondContact O-N 2.91Å; R437-D440 HydrophobicContact CB-CB 4.35Å; R437-D440 PolarHBondContact O-N 2.97Å; R437-Y441 WeakPolarHBondContact O-CD2 3.28Å
438N98Very high96Very high0 Ų024.1 Ų24.10%012%0.122CC..G310 helixtrans-51.2-53.3-179.6-69.5-43.1000113.1A209 Y414 G422 N424 D425 Y427 M429 D440 Y441A209-N438 VanDerWaalsContact CB-OD1 3.28Å; A209-N438 WeakPolarHBondContact CB-OD1 3.41Å; Y414-N438 HydrophobicContact CE1-CB 3.87Å; Y414-N438 WeakPolarHBondContact OH-CB 3.08Å; G422-N438 PolarHBondContact O-ND2 3.06Å; N424-N438 PolarHBondContact O-ND2 3.06Å; D425-N438 PolarHBondContact O-N 3.48Å; Y427-N438 PolarHBondContact O-N 2.69Å; Y427-N438 VanDerWaalsContact O-N 3.11Å; M429-N438 VanDerWaalsContact CG-OD1 3.23Å; M429-N438 WeakPolarHBondContact CG-OD1 3.11Å; N438-D440 VanDerWaalsContact C-N 3.26Å; N438-D440 PolarHBondContact O-N 3.47Å; N438-Y441 PolarHBondContact O-N 2.72Å; N438-Y441 VanDerWaalsContact O-N 3.1Å
439G96.1Very high95.8Very high0 Ų022.8 Ų22.80%012%0.118CC..G310 helixtrans-67.6-25.1-175.300000114.2R411 D425 R437 Y441 F442R411-G439 VanDerWaalsContact CZ-C 3.41Å; R411-G439 VanDerWaalsContact CZ-CA 3.49Å; R411-G439 PolarHBondContact NE-O 2.96Å; R411-G439 PolarHBondContact NH2-O 2.81Å; D425-G439 PolarHBondContact O-N 3.42Å; D425-G439 VanDerWaalsContact OD1-CA 3.3Å; D425-G439 WeakPolarHBondContact OD1-CA 3.33Å; R437-G439 PolarHBondContact O-N 2.91Å; G439-Y441 PolarHBondContact O-N 2.77Å; G439-Y441 VanDerWaalsContact O-N 3.13Å; G439-F442 PolarHBondContact O-N 3.15Å
440D95.9Very high95.8Very high80 Ų8022.9 Ų22.943%0.42812%0.118SC..G310 helixtrans-68.2-8.9175.6-69.4-18.8000112.9R437 N438 L443R437-D440 HydrophobicContact CB-CB 4.35Å; R437-D440 PolarHBondContact O-N 2.97Å; N438-D440 VanDerWaalsContact C-N 3.26Å; N438-D440 PolarHBondContact O-N 3.47Å; D440-L443 WeakPolarHBondContact O-CD2 3.34Å
441Y97.2Very high95.7Very high13 Ų1322.9 Ų22.95%0.05112%0.118CC..G310 helixtrans-118.27.7177.9-70.1-89.7000113.1F106 V216 M429 Y436 R437 N438 G439 L443 L448F106-Y441 AromaticContact CD2-CE1 3.97Å; F106-Y441 HydrophobicContact CD2-CE1 3.97Å; F106-Y441 HydrophobicContact CE2-CE1 4.09Å; V216-Y441 HydrophobicContact CG2-CD1 3.26Å; V216-Y441 HydrophobicContact CG2-CD2 3.68Å; V216-Y441 HydrophobicContact CG2-CE1 3.52Å; V216-Y441 HydrophobicContact CG2-CE2 3.96Å; V216-Y441 HydrophobicContact CG2-CG 3.34Å; M429-Y441 HydrophobicContact CE-CD2 3.78Å; M429-Y441 HydrophobicContact CE-CG 4.01Å; Y436-Y441 AromaticContact CD1-CE2 3.64Å; Y436-Y441 HydrophobicContact CD1-CE2 3.64Å; Y436-Y441 AromaticContact CD1-CZ 3.56Å; Y436-Y441 WeakPolarHBondContact CD1-OH 3.32Å; Y436-Y441 WeakPolarHBondContact CE1-OH 3.46Å; Y436-Y441 AromaticContact CG-CE2 3.97Å; Y436-Y441 HydrophobicContact CG-CE2 3.97Å; R437-Y441 WeakPolarHBondContact O-CD2 3.28Å; N438-Y441 PolarHBondContact O-N 2.72Å; N438-Y441 VanDerWaalsContact O-N 3.1Å; G439-Y441 PolarHBondContact O-N 2.77Å; G439-Y441 VanDerWaalsContact O-N 3.13Å; Y441-L443 PolarHBondContact O-N 2.91Å; Y441-L448 HydrophobicContact CD1-CD1 4.23Å; Y441-L448 HydrophobicContact CD1-CD2 3.99Å; Y441-L448 HydrophobicContact CE1-CD2 3.86Å
442F97.6Very high95.7Very high9 Ų922.8 Ų22.84%0.03912%0.118CC..SBendtrans-81.462.1167.4-167.7-109.1000111Y330 F400 W403 L404 P409 Y414 G439Y330-F442 AromaticContact CD1-CE2 3.99Å; Y330-F442 HydrophobicContact CD1-CE2 3.99Å; Y330-F442 HydrophobicContact CD1-CZ 4.26Å; Y330-F442 HydrophobicContact CD2-CD2 4.47Å; Y330-F442 AromaticContact CD2-CE2 3.37Å; Y330-F442 HydrophobicContact CD2-CE2 3.37Å; Y330-F442 AromaticContact CD2-CZ 3.82Å; Y330-F442 HydrophobicContact CD2-CZ 3.82Å; Y330-F442 HydrophobicContact CE1-CD2 4.45Å; Y330-F442 HydrophobicContact CE1-CE2 4.05Å; Y330-F442 HydrophobicContact CE2-CD2 4.17Å; Y330-F442 AromaticContact CE2-CE2 3.42Å; Y330-F442 HydrophobicContact CE2-CE2 3.42Å; Y330-F442 VanDerWaalsContact CE2-CE2 3.42Å; Y330-F442 HydrophobicContact CE2-CZ 4.32Å; Y330-F442 AromaticContact CG-CE2 3.66Å; Y330-F442 HydrophobicContact CG-CE2 3.66Å; Y330-F442 AromaticContact CG-CZ 3.78Å; Y330-F442 HydrophobicContact CG-CZ 3.78Å; Y330-F442 AromaticContact CZ-CE2 3.78Å; F400-F442 HydrophobicContact CE2-CD2 4.09Å; F400-F442 AromaticContact CE2-CE2 3.77Å; F400-F442 HydrophobicContact CE2-CE2 3.77Å; F400-F442 AromaticContact CZ-CD2 3.61Å; F400-F442 HydrophobicContact CZ-CD2 3.61Å; F400-F442 AromaticContact CZ-CE2 3.81Å; F400-F442 HydrophobicContact CZ-CE2 3.81Å; W403-F442 AromaticContact CH2-CZ 3.87Å; W403-F442 HydrophobicContact CH2-CZ 3.87Å; W403-F442 AromaticContact CZ3-CE2 3.95Å; W403-F442 HydrophobicContact CZ3-CE2 3.95Å; W403-F442 AromaticContact CZ3-CZ 3.57Å; W403-F442 HydrophobicContact CZ3-CZ 3.57Å; L404-F442 HydrophobicContact CD2-CE2 4.33Å; L404-F442 HydrophobicContact CD2-CZ 4.31Å; P409-F442 HydrophobicContact CB-CE1 4.25Å; P409-F442 HydrophobicContact CB-CZ 4.46Å; P409-F442 HydrophobicContact CG-CE1 3.83Å; P409-F442 HydrophobicContact CG-CZ 3.97Å; Y414-F442 HydrophobicContact CD2-CB 3.91Å; Y414-F442 HydrophobicContact CD2-CD1 4.43Å; Y414-F442 AromaticContact CD2-CD2 3.6Å; Y414-F442 HydrophobicContact CD2-CD2 3.6Å; Y414-F442 HydrophobicContact CD2-CE2 4.24Å; Y414-F442 AromaticContact CD2-CG 3.72Å; Y414-F442 HydrophobicContact CD2-CG 3.72Å; Y414-F442 HydrophobicContact CE2-CD2 4.38Å; Y414-F442 HydrophobicContact CG-CB 4.31Å; Y414-F442 HydrophobicContact CG-CG 4.24Å; G439-F442 PolarHBondContact O-N 3.15Å
443L95.3Very high95.6Very high43 Ų4323.3 Ų23.323%0.22512%0.122CC..SBendtrans-155.1161-172.659.789.8000111.9R215 D440 Y441 V447 L448R215-L443 PolarHBondContact NH1-O 3Å; D440-L443 WeakPolarHBondContact O-CD2 3.34Å; Y441-L443 PolarHBondContact O-N 2.91Å; L443-V447 HydrophobicContact CD1-CB 3.6Å; L443-V447 HydrophobicContact CD1-CG1 3.85Å; L443-V447 HydrophobicContact CD1-CG2 4.24Å; L443-L448 HydrophobicContact CD1-CD1 4.21Å; L443-L448 HydrophobicContact CD1-CD2 4Å; L443-L448 HydrophobicContact CD1-CG 3.84Å
444S95.2Very high95.6Very high37 Ų3725.2 Ų25.226%0.25913%0.129SC..  trans-63143.9-175.2171.80000113.9E401 K446 V447E401-S444 PolarHBondContact OE1-OG 3.24Å; E401-S444 VanDerWaalsContact OE2-CA 3.26Å; E401-S444 WeakPolarHBondContact OE2-CA 3.17Å; E401-S444 PolarHBondContact OE2-OG 3.11Å; S444-K446 PolarHBondContact O-N 2.83Å; S444-K446 VanDerWaalsContact O-N 3.14Å; S444-K446 PolarHBondContact OG-N 3.38Å; S444-V447 WeakPolarHBondContact O-CB 3.39Å; S444-V447 PolarHBondContact O-N 3.24Å
445N95.3Very high95.6Very high0 Ų025.5 Ų25.50%013%0.13CC..G310 helixtrans-57-28.7179.2-67-3.6000113.9R215 D397 E401 V447 L448 G449 Y450 Y452R215-N445 PolarHBondContact NE-OD1 3.35Å; R215-N445 PolarHBondContact NH1-OD1 3.17Å; R215-N445 VanDerWaalsContact NH1-OD1 3.11Å; R215-N445 PolarHBondContact NH2-OD1 3.5Å; D397-N445 PolarHBondContact OD2-ND2 3.38Å; E401-N445 HydrophobicContact CG-CB 4.35Å; E401-N445 PolarHBondContact OE2-N 3.12Å; E401-N445 PolarHBondContact OE2-OD1 2.92Å; N445-V447 PolarHBondContact O-N 2.87Å; N445-L448 CarbonylContact O-C 3.47Å; N445-L448 WeakPolarHBondContact O-CA 3.34Å; N445-L448 WeakPolarHBondContact O-CB 3.24Å; N445-L448 PolarHBondContact O-N 3.37Å; N445-G449 PolarHBondContact O-N 2.85Å; N445-G449 VanDerWaalsContact O-N 3.12Å; N445-Y450 CarbonylContact C-O 3.37Å; N445-Y450 HydrophobicContact CB-CD1 4.18Å; N445-Y450 HydrophobicContact CB-CD2 4.16Å; N445-Y450 HydrophobicContact CB-CE1 3.82Å; N445-Y450 HydrophobicContact CB-CE2 3.83Å; N445-Y450 HydrophobicContact CB-CG 4.35Å; N445-Y450 VanDerWaalsContact CB-O 3.31Å; N445-Y450 WeakPolarHBondContact CB-O 3.37Å; N445-Y450 VanDerWaalsContact CG-CE2 3.49Å; N445-Y450 WeakPolarHBondContact ND2-CE2 3.46Å; N445-Y450 VanDerWaalsContact ND2-CZ 3.31Å; N445-Y450 PolarHBondContact ND2-OH 3.06Å; N445-Y450 PolarHBondContact O-N 2.82Å; N445-Y450 VanDerWaalsContact O-O 3.09Å; N445-Y450 PolarHBondContact OD1-OH 3.36Å; N445-Y452 VanDerWaalsContact ND2-CE2 3.33Å; N445-Y452 WeakPolarHBondContact ND2-CE2 3.34Å
446K91.1Very high95.3Very high68 Ų6824.8 Ų24.830%0.29613%0.126SC..G310 helixtrans-55.9-40.5175.4-72-169.7175-175.70111.3Y116 S444 L448 G449 E451Y116-K446 PolarHBondContact OH-O 3.46Å; S444-K446 PolarHBondContact O-N 2.83Å; S444-K446 VanDerWaalsContact O-N 3.14Å; S444-K446 PolarHBondContact OG-N 3.38Å; K446-L448 PolarHBondContact O-N 2.93Å; K446-G449 PolarHBondContact O-N 3.09Å; K446-E451 WeakPolarHBondContact CE-OE2 3.18Å
447V93.8Very high94.5Very high78 Ų7827.7 Ų27.747%0.47314%0.144SC..G310 helixtrans-66-26.3178.2179.50000111.9L443 S444 N445 G449L443-V447 HydrophobicContact CD1-CB 3.6Å; L443-V447 HydrophobicContact CD1-CG1 3.85Å; L443-V447 HydrophobicContact CD1-CG2 4.24Å; S444-V447 WeakPolarHBondContact O-CB 3.39Å; S444-V447 PolarHBondContact O-N 3.24Å; N445-V447 PolarHBondContact O-N 2.87Å; V447-G449 VanDerWaalsContact C-N 3.3Å
448L96.4Very high93.4Very high4 Ų430.2 Ų30.22%0.02117%0.168CC..G310 helixtrans-88.71.4177.3-55.4173.1000112.4F106 G107 R215 L219 Y441 L443 N445 K446 Y450F106-L448 CarbonylContact C-O 3.56Å; F106-L448 VanDerWaalsContact C-O 3.3Å; F106-L448 HydrophobicContact CB-CB 4.43Å; G107-L448 WeakPolarHBondContact CA-O 3.11Å; G107-L448 PolarHBondContact N-O 2.99Å; G107-L448 VanDerWaalsContact N-O 3.13Å; R215-L448 HydrophobicContact CG-CD1 4.1Å; L219-L448 HydrophobicContact CD1-CB 4.29Å; L219-L448 HydrophobicContact CD1-CD1 3.91Å; Y441-L448 HydrophobicContact CD1-CD1 4.23Å; Y441-L448 HydrophobicContact CD1-CD2 3.99Å; Y441-L448 HydrophobicContact CE1-CD2 3.86Å; L443-L448 HydrophobicContact CD1-CD1 4.21Å; L443-L448 HydrophobicContact CD1-CD2 4Å; L443-L448 HydrophobicContact CD1-CG 3.84Å; N445-L448 CarbonylContact O-C 3.47Å; N445-L448 WeakPolarHBondContact O-CA 3.34Å; N445-L448 WeakPolarHBondContact O-CB 3.24Å; N445-L448 PolarHBondContact O-N 3.37Å; K446-L448 PolarHBondContact O-N 2.93Å; L448-Y450 HydrophobicContact CB-CD1 3.85Å; L448-Y450 HydrophobicContact CB-CE1 3.69Å; L448-Y450 HydrophobicContact CD1-CE1 4.04Å; L448-Y450 HydrophobicContact CG-CE1 4.5Å
449G95.8Very high92Very high4 Ų432.7 Ų32.74%0.04119%0.193CC..THydrogen-bonded Turntrans69.836.2176.900000114.5E118 S119 N445 K446 V447E118-G449 CarbonylContact C-O 3.47Å; E118-G449 VanDerWaalsContact CA-O 3.31Å; E118-G449 WeakPolarHBondContact CA-O 3.44Å; S119-G449 PolarHBondContact N-O 3.15Å; N445-G449 PolarHBondContact O-N 2.85Å; N445-G449 VanDerWaalsContact O-N 3.12Å; K446-G449 PolarHBondContact O-N 3.09Å; V447-G449 VanDerWaalsContact C-N 3.3Å
450Y97.3Very high90.9Very high2 Ų236.5 Ų36.51%0.00821%0.211CC..EExtended strand (participates in β ladder)trans-144.8162166.674.7-78000112.9S119 R121 L219 D397 N445 L448 Y452S119-Y450 CarbonylContact O-C 3.23Å; S119-Y450 WeakPolarHBondContact O-CA 3.3Å; S119-Y450 WeakPolarHBondContact O-CB 3.46Å; R121-Y450 HydrophobicContact CG-CD2 4.39Å; L219-Y450 HydrophobicContact CD1-CE1 4.08Å; L219-Y450 HydrophobicContact CD2-CD1 3.77Å; L219-Y450 HydrophobicContact CD2-CE1 3.71Å; L219-Y450 HydrophobicContact CG-CE1 4.19Å; D397-Y450 WeakPolarHBondContact OD2-CE2 3.45Å; D397-Y450 PolarHBondContact OD2-OH 3.45Å; N445-Y450 CarbonylContact C-O 3.37Å; N445-Y450 HydrophobicContact CB-CD1 4.18Å; N445-Y450 HydrophobicContact CB-CD2 4.16Å; N445-Y450 HydrophobicContact CB-CE1 3.82Å; N445-Y450 HydrophobicContact CB-CE2 3.83Å; N445-Y450 HydrophobicContact CB-CG 4.35Å; N445-Y450 VanDerWaalsContact CB-O 3.31Å; N445-Y450 WeakPolarHBondContact CB-O 3.37Å; N445-Y450 VanDerWaalsContact CG-CE2 3.49Å; N445-Y450 WeakPolarHBondContact ND2-CE2 3.46Å; N445-Y450 VanDerWaalsContact ND2-CZ 3.31Å; N445-Y450 PolarHBondContact ND2-OH 3.06Å; N445-Y450 PolarHBondContact O-N 2.82Å; N445-Y450 VanDerWaalsContact O-O 3.09Å; N445-Y450 PolarHBondContact OD1-OH 3.36Å; L448-Y450 HydrophobicContact CB-CD1 3.85Å; L448-Y450 HydrophobicContact CB-CE1 3.69Å; L448-Y450 HydrophobicContact CD1-CE1 4.04Å; L448-Y450 HydrophobicContact CG-CE1 4.5Å; Y450-Y452 HydrophobicContact CD2-CE2 4.42Å; Y450-Y452 AromaticContact CE2-CE2 3.83Å; Y450-Y452 HydrophobicContact CE2-CE2 3.83Å
451E95.9Very high89.9Confident0 Ų037.7 Ų37.70%021%0.209CC..EExtended strand (participates in β ladder)trans-146157.8-177.1-175.358.1-80.100111.2E118 S119 V120 R121 R405 K446 L456E118-E451 HydrophobicContact CG-CB 4.16Å; E118-E451 WeakPolarHBondContact OE1-CB 3.22Å; S119-E451 PolarHBondContact O-N 3.33Å; V120-E451 CarbonylContact C-O 3.53Å; V120-E451 WeakPolarHBondContact CA-O 3.38Å; R121-E451 PolarHBondContact N-O 3.16Å; R405-E451 IonicContact CZ-OE1 2.72Å; R405-E451 IonicContact CZ-OE2 2.75Å; R405-E451 IonicContact NH1-OE1 3.26Å; R405-E451 IonicContact NH1-OE2 3.6Å; R405-E451 PolarHBondContact NH1-OE2 3.2Å; R405-E451 IonicContact NH2-OE1 2.63Å; R405-E451 PolarHBondContact NH2-OE1 2.82Å; R405-E451 IonicContact NH2-OE2 3.13Å; R405-E451 PolarHBondContact NH2-OE2 3.04Å; K446-E451 WeakPolarHBondContact CE-OE2 3.18Å; E451-L456 HydrophobicContact CB-CD2 4.3Å; E451-L456 HydrophobicContact CG-CD2 3.45Å; E451-L456 VanDerWaalsContact CG-CD2 3.45Å; E451-L456 HydrophobicContact CG-CG 4.1Å
452Y96.8Very high88.7Confident0 Ų042.8 Ų42.80%023%0.232CC..EExtended strand (participates in β ladder)trans-97.8131.1172.6-72.6-80.9000111.3R121 Y238 A394 D397 S398 N445 Y450 Y454 L455 L456R121-Y452 HydrophobicContact CB-CD1 3.74Å; R121-Y452 HydrophobicContact CB-CE1 3.7Å; R121-Y452 HydrophobicContact CG-CE1 4.29Å; R121-Y452 PolarHBondContact NH1-OH 2.99Å; R121-Y452 VanDerWaalsContact NH1-OH 3.08Å; Y238-Y452 AromaticContact CD1-CD1 3.53Å; Y238-Y452 HydrophobicContact CD1-CD1 3.53Å; Y238-Y452 AromaticContact CD1-CE1 3.87Å; Y238-Y452 HydrophobicContact CD1-CE1 3.87Å; Y238-Y452 AromaticContact CE1-CD1 3.79Å; Y238-Y452 HydrophobicContact CE1-CD1 3.79Å; Y238-Y452 HydrophobicContact CG-CD1 4.33Å; Y238-Y452 HydrophobicContact CG-CE1 4.4Å; A394-Y452 WeakPolarHBondContact O-CE1 3.36Å; A394-Y452 PolarHBondContact O-OH 3.45Å; D397-Y452 WeakPolarHBondContact CB-OH 3.31Å; D397-Y452 WeakPolarHBondContact OD2-CE2 3.29Å; D397-Y452 PolarHBondContact OD2-OH 2.91Å; S398-Y452 VanDerWaalsContact CA-CE2 3.45Å; S398-Y452 VanDerWaalsContact CB-CD2 3.48Å; N445-Y452 VanDerWaalsContact ND2-CE2 3.33Å; N445-Y452 WeakPolarHBondContact ND2-CE2 3.34Å; Y450-Y452 HydrophobicContact CD2-CE2 4.42Å; Y450-Y452 AromaticContact CE2-CE2 3.83Å; Y450-Y452 HydrophobicContact CE2-CE2 3.83Å; Y452-Y454 PolarHBondContact O-N 3.33Å; Y452-L455 HydrophobicContact CD2-CD1 4.4Å; Y452-L455 WeakPolarHBondContact O-CA 3.45Å; Y452-L455 PolarHBondContact O-N 2.8Å; Y452-L456 PolarHBondContact O-N 2.03Å
453A94.6Very high87.5Confident11 Ų1145.8 Ų45.89%0.09125%0.251CS..G310 helixtrans-53.3-35.8-17400000114.3V120 R121 R122 L455V120-A453 HydrophobicContact CG1-CB 3.82Å; R121-A453 PolarHBondContact O-N 2.88Å; R122-A453 HydrophobicContact CG-CB 4.36Å; A453-L455 VanDerWaalsContact C-N 3.32Å
454Y92.8Very high86.6Confident45 Ų4545.4 Ų45.418%0.17625%0.248CC..G310 helixtrans-80.6-12.1-179.581.4-85.9000114Y238 F395 S398 Y452Y238-Y454 HydrophobicContact CE1-CD1 4.32Å; Y238-Y454 HydrophobicContact CE2-CD1 4.11Å; Y238-Y454 HydrophobicContact CE2-CE1 4.34Å; Y238-Y454 AromaticContact CZ-CD1 3.66Å; Y238-Y454 VanDerWaalsContact OH-CD1 3.32Å; Y238-Y454 WeakPolarHBondContact OH-CD1 3.27Å; F395-Y454 HydrophobicContact CE2-CE1 4.47Å; S398-Y454 WeakPolarHBondContact CB-OH 3.4Å; S398-Y454 WeakPolarHBondContact OG-CE1 3.44Å; S398-Y454 PolarHBondContact OG-OH 3.36Å; Y452-Y454 PolarHBondContact O-N 3.33Å
455L92.8Very high85.6Confident26 Ų2647.5 Ų47.514%0.13625%0.254CS..G310 helixtrans-99.3-1.7176.4-62.7-178.2000112.5E401 R402 R405 Y452 A453E401-L455 HydrophobicContact CB-CD1 4.18Å; E401-L455 HydrophobicContact CG-CD1 3.9Å; R402-L455 HydrophobicContact CB-CD2 4.4Å; R402-L455 HydrophobicContact CG-CD2 4.48Å; R405-L455 PolarHBondContact NH1-O 3.01Å; Y452-L455 HydrophobicContact CD2-CD1 4.4Å; Y452-L455 WeakPolarHBondContact O-CA 3.45Å; Y452-L455 PolarHBondContact O-N 2.8Å; A453-L455 VanDerWaalsContact C-N 3.32Å
456L89Confident84.4Confident15 Ų1553 Ų538%0.07928%0.278CS..SBendtrans-62.4146.1175.1-72.4172.4000111.5V120 E451 Y452 Q460 R461 Q464V120-L456 HydrophobicContact CG1-CD1 4.24Å; E451-L456 HydrophobicContact CB-CD2 4.3Å; E451-L456 HydrophobicContact CG-CD2 3.45Å; E451-L456 VanDerWaalsContact CG-CD2 3.45Å; E451-L456 HydrophobicContact CG-CG 4.1Å; Y452-L456 PolarHBondContact O-N 2.03Å; L456-Q460 HydrophobicContact CB-CB 4.05Å; L456-Q460 HydrophobicContact CD2-CB 4.04Å; L456-Q460 HydrophobicContact CG-CB 4.45Å; L456-R461 HydrophobicContact CB-CB 4.06Å; L456-Q464 HydrophobicContact CD1-CB 3.84Å; L456-Q464 HydrophobicContact CD1-CG 4.03Å
457D79.9Confident83.4Confident89 Ų8952.1 Ų52.148%0.47628%0.278SS..  trans-59.5150.5172-67.6-48.2000110.2G459 Q460 R461D457-G459 PolarHBondContact O-N 3.4Å; D457-Q460 HydrophobicContact CB-CG 4.48Å; D457-Q460 WeakPolarHBondContact O-CA 3.25Å; D457-Q460 WeakPolarHBondContact O-CB 3.12Å; D457-Q460 PolarHBondContact O-N 2.47Å; D457-R461 WeakPolarHBondContact O-CB 3.45Å; D457-R461 PolarHBondContact O-N 3.18Å
458P74.8Confident82.6Confident111 Ų11149.9 Ų49.972%0.72126%0.264SS*.Hα-helixtrans-52-38.2-171.8-2934.5000114.8F462P458-F462 PolarHBondContact O-N 2.8Å
459G68.9Low81.5Confident52 Ų5251.9 Ų51.954%0.53628%0.278SS..Hα-helixtrans-69.5-40.5176.400000113.5D457 F462 V463D457-G459 PolarHBondContact O-N 3.4Å; G459-F462 PolarHBondContact O-N 3.29Å; G459-V463 WeakPolarHBondContact O-CG2 3.31Å; G459-V463 PolarHBondContact O-N 2.99Å
460Q73.7Confident80.4Confident80 Ų8059.5 Ų59.537%0.37431%0.306SS..Hα-helixtrans-69-40175.9-66.6179.4-40.900111.1L456 D457 F462 V463 Q464L456-Q460 HydrophobicContact CB-CB 4.05Å; L456-Q460 HydrophobicContact CD2-CB 4.04Å; L456-Q460 HydrophobicContact CG-CB 4.45Å; D457-Q460 HydrophobicContact CB-CG 4.48Å; D457-Q460 WeakPolarHBondContact O-CA 3.25Å; D457-Q460 WeakPolarHBondContact O-CB 3.12Å; D457-Q460 PolarHBondContact O-N 2.47Å; Q460-F462 VanDerWaalsContact C-N 3.34Å; Q460-F462 PolarHBondContact O-N 3.16Å; Q460-V463 PolarHBondContact O-N 3.33Å; Q460-Q464 WeakPolarHBondContact O-CB 3.2Å; Q460-Q464 PolarHBondContact O-N 3.09Å
461R74Confident79.2Confident105 Ų10564.7 Ų64.740%0.39633%0.334SS..Hα-helixtrans-61.1-42.2175.2-170.4175.9178.5-178.8-0.7111.6L456 D457 V463 Q464 E465L456-R461 HydrophobicContact CB-CB 4.06Å; D457-R461 WeakPolarHBondContact O-CB 3.45Å; D457-R461 PolarHBondContact O-N 3.18Å; R461-V463 PolarHBondContact O-N 3.36Å; R461-Q464 PolarHBondContact O-N 3.47Å; R461-E465 HydrophobicContact CG-CG 4.17Å; R461-E465 IonicContact CZ-OE1 3.95Å; R461-E465 IonicContact NE-OE1 3.37Å; R461-E465 PolarHBondContact NE-OE1 2.61Å; R461-E465 IonicContact NE-OE2 3.9Å; R461-E465 PolarHBondContact NE-OE2 2.8Å; R461-E465 IonicContact NH2-OE1 3.46Å; R461-E465 PolarHBondContact NH2-OE1 2.79Å; R461-E465 IonicContact NH2-OE2 2.59Å; R461-E465 WeakPolarHBondContact O-CB 3.36Å; R461-E465 PolarHBondContact O-N 3.48Å
462F72.3Confident78.1Confident120 Ų12069.2 Ų69.253%0.52636%0.355SS..Hα-helixtrans-58.5-47174.2175.4-98.7000111.9P458 G459 Q460 Q464 F466 V467P458-F462 PolarHBondContact O-N 2.8Å; G459-F462 PolarHBondContact O-N 3.29Å; Q460-F462 VanDerWaalsContact C-N 3.34Å; Q460-F462 PolarHBondContact O-N 3.16Å; F462-Q464 VanDerWaalsContact C-N 3.34Å; F462-Q464 PolarHBondContact O-N 3.25Å; F462-F466 HydrophobicContact CD2-CB 4.17Å; F462-F466 AromaticContact CD2-CD2 3.77Å; F462-F466 HydrophobicContact CD2-CD2 3.77Å; F462-F466 HydrophobicContact CD2-CE2 4.48Å; F462-F466 HydrophobicContact CD2-CG 4.13Å; F462-F466 HydrophobicContact CE2-CB 3.99Å; F462-F466 HydrophobicContact CE2-CD2 4.24Å; F462-F466 HydrophobicContact CE2-CG 4.15Å; F462-F466 HydrophobicContact CZ-CB 4.43Å; F462-F466 WeakPolarHBondContact O-CA 3.45Å; F462-F466 VanDerWaalsContact O-CB 3.31Å; F462-F466 WeakPolarHBondContact O-CB 3.2Å; F462-F466 PolarHBondContact O-N 2.99Å; F462-V467 HydrophobicContact CD1-CG2 4.17Å; F462-V467 HydrophobicContact CE1-CG2 3.75Å; F462-V467 HydrophobicContact CZ-CG2 4.41Å
463V71.1Confident76.9Confident71 Ų7174.7 Ų74.743%0.4338%0.38SS..Iπ-helixtrans-60.1-47.7176.5175.10000110.3G459 Q460 R461 V467 T468G459-V463 WeakPolarHBondContact O-CG2 3.31Å; G459-V463 PolarHBondContact O-N 2.99Å; Q460-V463 PolarHBondContact O-N 3.33Å; R461-V463 PolarHBondContact O-N 3.36Å; V463-V467 HydrophobicContact CG1-CB 4.27Å; V463-V467 CarbonylContact O-C 3.36Å; V463-V467 WeakPolarHBondContact O-CA 3.46Å; V463-V467 WeakPolarHBondContact O-CB 3.25Å; V463-V467 PolarHBondContact O-N 3.4Å; V463-T468 PolarHBondContact O-N 2.78Å; V463-T468 PolarHBondContact O-OG1 3.27Å; V463-T468 VanDerWaalsContact O-OG1 3.1Å
464Q76.9Confident75.8Confident35 Ų3576.6 Ų76.616%0.16440%0.396CS..Iπ-helixtrans-67.2-43-175.7-17261.915.100113.7V120 L456 Q460 R461 F462V120-Q464 HydrophobicContact CG1-CG 4.41Å; L456-Q464 HydrophobicContact CD1-CB 3.84Å; L456-Q464 HydrophobicContact CD1-CG 4.03Å; Q460-Q464 WeakPolarHBondContact O-CB 3.2Å; Q460-Q464 PolarHBondContact O-N 3.09Å; R461-Q464 PolarHBondContact O-N 3.47Å; F462-Q464 VanDerWaalsContact C-N 3.34Å; F462-Q464 PolarHBondContact O-N 3.25Å
465E74Confident74.9Confident82 Ų8281.8 Ų81.838%0.38342%0.42SS..Iπ-helixtrans-83.7-33.2-176.7-70.1-178.517500112.5R461R461-E465 HydrophobicContact CG-CG 4.17Å; R461-E465 IonicContact CZ-OE1 3.95Å; R461-E465 IonicContact NE-OE1 3.37Å; R461-E465 PolarHBondContact NE-OE1 2.61Å; R461-E465 IonicContact NE-OE2 3.9Å; R461-E465 PolarHBondContact NE-OE2 2.8Å; R461-E465 IonicContact NH2-OE1 3.46Å; R461-E465 PolarHBondContact NH2-OE1 2.79Å; R461-E465 IonicContact NH2-OE2 2.59Å; R461-E465 WeakPolarHBondContact O-CB 3.36Å; R461-E465 PolarHBondContact O-N 3.48Å
466F70.1Confident73.9Confident115 Ų11587 Ų8750%0.50444%0.444SS..Iπ-helixtrans-116.3-25.6-170.4-62.8-89.5000115.1F462 Y470F462-F466 HydrophobicContact CD2-CB 4.17Å; F462-F466 AromaticContact CD2-CD2 3.77Å; F462-F466 HydrophobicContact CD2-CD2 3.77Å; F462-F466 HydrophobicContact CD2-CE2 4.48Å; F462-F466 HydrophobicContact CD2-CG 4.13Å; F462-F466 HydrophobicContact CE2-CB 3.99Å; F462-F466 HydrophobicContact CE2-CD2 4.24Å; F462-F466 HydrophobicContact CE2-CG 4.15Å; F462-F466 HydrophobicContact CZ-CB 4.43Å; F462-F466 WeakPolarHBondContact O-CA 3.45Å; F462-F466 VanDerWaalsContact O-CB 3.31Å; F462-F466 WeakPolarHBondContact O-CB 3.2Å; F462-F466 PolarHBondContact O-N 2.99Å; F466-Y470 WeakPolarHBondContact O-CD2 3.01Å; F466-Y470 WeakPolarHBondContact O-CE2 3.41Å
467V71.3Confident73.3Confident49 Ų4990.3 Ų90.330%0.29746%0.46SS..Iπ-helixtrans-100.2-46.9-175.8-177.90000110.9F462 V463 Y470 L471F462-V467 HydrophobicContact CD1-CG2 4.17Å; F462-V467 HydrophobicContact CE1-CG2 3.75Å; F462-V467 HydrophobicContact CZ-CG2 4.41Å; V463-V467 HydrophobicContact CG1-CB 4.27Å; V463-V467 CarbonylContact O-C 3.36Å; V463-V467 WeakPolarHBondContact O-CA 3.46Å; V463-V467 WeakPolarHBondContact O-CB 3.25Å; V463-V467 PolarHBondContact O-N 3.4Å; V467-Y470 PolarHBondContact O-N 3.44Å; V467-L471 HydrophobicContact CG1-CD1 3.76Å; V467-L471 HydrophobicContact CG1-CG 4.08Å; V467-L471 WeakPolarHBondContact O-CG 3.29Å; V467-L471 PolarHBondContact O-N 2.89Å
468T75.6Confident73.2Confident31 Ų3194 Ų9419%0.1947%0.468CS..Hα-helixtrans-55.1-47.1-177.7-53.30000112.9V463 Y470 L471 E472V463-T468 PolarHBondContact O-N 2.78Å; V463-T468 PolarHBondContact O-OG1 3.27Å; V463-T468 VanDerWaalsContact O-OG1 3.1Å; T468-Y470 VanDerWaalsContact C-N 3.32Å; T468-Y470 PolarHBondContact O-N 2.84Å; T468-L471 PolarHBondContact O-N 3.25Å; T468-E472 HydrophobicContact CG2-CG 4.47Å; T468-E472 WeakPolarHBondContact O-CG 3.37Å; T468-E472 PolarHBondContact O-N 3.07Å
469P74.9Confident73.3Confident47 Ų4795.5 Ų95.531%0.30547%0.465SS..Hα-helixtrans-61.7-38.4179.9-23.335000113.3E472 Q473P469-E472 PolarHBondContact O-N 2.9Å; P469-Q473 WeakPolarHBondContact O-CB 3.4Å; P469-Q473 PolarHBondContact O-N 3.48Å
470Y71.8Confident73.9Confident164 Ų164103.1 Ų103.164%0.64348%0.478SS*.Hα-helixtrans-69.3-38.1177.3-76.5-95.7000111.8F466 V467 T468 A474F466-Y470 WeakPolarHBondContact O-CD2 3.01Å; F466-Y470 WeakPolarHBondContact O-CE2 3.41Å; V467-Y470 PolarHBondContact O-N 3.44Å; T468-Y470 VanDerWaalsContact C-N 3.32Å; T468-Y470 PolarHBondContact O-N 2.84Å; Y470-A474 WeakPolarHBondContact O-CB 3.48Å; Y470-A474 PolarHBondContact O-N 3.04Å
471L71.2Confident74.2Confident111 Ų111104.1 Ų104.158%0.58149%0.485SS*.Hα-helixtrans-65.5-41.5176-72.3175.9000111.8V467 T468 A474 K475V467-L471 HydrophobicContact CG1-CD1 3.76Å; V467-L471 HydrophobicContact CG1-CG 4.08Å; V467-L471 WeakPolarHBondContact O-CG 3.29Å; V467-L471 PolarHBondContact O-N 2.89Å; T468-L471 PolarHBondContact O-N 3.25Å; L471-A474 PolarHBondContact O-N 3.4Å; L471-K475 WeakPolarHBondContact O-CB 3.39Å; L471-K475 PolarHBondContact O-N 2.68Å
472E73.9Confident74.7Confident95 Ų95103.5 Ų103.544%0.44449%0.489SS..Hα-helixtrans-62.8-49175.5-73.2-177158.500111.2T468 P469 A474 K475 E476T468-E472 HydrophobicContact CG2-CG 4.47Å; T468-E472 WeakPolarHBondContact O-CG 3.37Å; T468-E472 PolarHBondContact O-N 3.07Å; P469-E472 PolarHBondContact O-N 2.9Å; E472-A474 VanDerWaalsContact C-N 3.31Å; E472-A474 PolarHBondContact O-N 2.87Å; E472-K475 WeakPolarHBondContact O-CB 3.31Å; E472-K475 PolarHBondContact O-N 2.98Å; E472-K475 VanDerWaalsContact O-N 3.09Å; E472-E476 PolarHBondContact O-N 3.13Å
473Q71.4Confident75.2Confident114 Ų11499.7 Ų99.753%0.53348%0.483SS..Hα-helixtrans-60.1-42.3176.2-168.3178.81500111.6P469 K475 E476 I477P469-Q473 WeakPolarHBondContact O-CB 3.4Å; P469-Q473 PolarHBondContact O-N 3.48Å; Q473-K475 VanDerWaalsContact C-N 3.32Å; Q473-K475 PolarHBondContact O-N 3.02Å; Q473-E476 PolarHBondContact O-N 3.03Å; Q473-I477 HydrophobicContact CG-CD1 3.98Å; Q473-I477 WeakPolarHBondContact O-CD1 3.19Å; Q473-I477 VanDerWaalsContact O-CG1 3.24Å; Q473-I477 WeakPolarHBondContact O-CG1 3.27Å; Q473-I477 PolarHBondContact O-N 3.47Å
474A71.1Confident75.9Confident51 Ų5199.2 Ų99.242%0.42149%0.487SS..Hα-helixtrans-62.3-39.6175.700000111.6Y470 L471 E472 I477 W478Y470-A474 WeakPolarHBondContact O-CB 3.48Å; Y470-A474 PolarHBondContact O-N 3.04Å; L471-A474 PolarHBondContact O-N 3.4Å; E472-A474 VanDerWaalsContact C-N 3.31Å; E472-A474 PolarHBondContact O-N 2.87Å; A474-I477 PolarHBondContact O-N 2.95Å; A474-W478 VanDerWaalsContact O-CB 3.23Å; A474-W478 WeakPolarHBondContact O-CB 3.49Å; A474-W478 PolarHBondContact O-N 2.88Å
475K74.1Confident76.4Confident154 Ų15499.7 Ų99.767%0.6750%0.501SS*.Hα-helixtrans-65.7-40.2178.9-166.1178.5-178.4-176.80112.1L471 E472 Q473 W478 Q479L471-K475 WeakPolarHBondContact O-CB 3.39Å; L471-K475 PolarHBondContact O-N 2.68Å; E472-K475 WeakPolarHBondContact O-CB 3.31Å; E472-K475 PolarHBondContact O-N 2.98Å; E472-K475 VanDerWaalsContact O-N 3.09Å; Q473-K475 VanDerWaalsContact C-N 3.32Å; Q473-K475 PolarHBondContact O-N 3.02Å; K475-W478 PolarHBondContact O-N 3.45Å; K475-Q479 PolarHBondContact O-N 3.06Å
476E72.8Confident77.2Confident137 Ų137101.1 Ų101.164%0.6451%0.51SS*.Hα-helixtrans-64.9-45.4173.6-71-169.2159.700111.8E472 Q473 W478 Q479E472-E476 PolarHBondContact O-N 3.13Å; Q473-E476 PolarHBondContact O-N 3.03Å; E476-W478 VanDerWaalsContact C-N 3.31Å; E476-W478 PolarHBondContact O-N 3.03Å; E476-Q479 PolarHBondContact O-N 3.39Å
477I76.6Confident78.2Confident84 Ų84100.6 Ų100.643%0.43151%0.512SS..Hα-helixtrans-65-37.1178-66166.4000111Q473 A474 Q479 W480 L481Q473-I477 HydrophobicContact CG-CD1 3.98Å; Q473-I477 WeakPolarHBondContact O-CD1 3.19Å; Q473-I477 VanDerWaalsContact O-CG1 3.24Å; Q473-I477 WeakPolarHBondContact O-CG1 3.27Å; Q473-I477 PolarHBondContact O-N 3.47Å; A474-I477 PolarHBondContact O-N 2.95Å; I477-Q479 VanDerWaalsContact C-N 3.29Å; I477-Q479 PolarHBondContact O-N 2.89Å; I477-W480 WeakPolarHBondContact O-CB 3.35Å; I477-W480 PolarHBondContact O-N 3.31Å; I477-W480 VanDerWaalsContact O-N 3.12Å; I477-L481 HydrophobicContact CG2-CD1 3.73Å; I477-L481 HydrophobicContact CG2-CG 3.94Å; I477-L481 WeakPolarHBondContact O-CG 3.3Å; I477-L481 PolarHBondContact O-N 2.89Å
478W75.9Confident79.1Confident166 Ų166100 Ų10063%0.62952%0.516SS*.Hα-helixtrans-61.8-36.6-177.3-163.5-104.9000112.6A474 K475 E476 L481 L482A474-W478 VanDerWaalsContact O-CB 3.23Å; A474-W478 WeakPolarHBondContact O-CB 3.49Å; A474-W478 PolarHBondContact O-N 2.88Å; K475-W478 PolarHBondContact O-N 3.45Å; E476-W478 VanDerWaalsContact C-N 3.31Å; E476-W478 PolarHBondContact O-N 3.03Å; W478-L481 HydrophobicContact CE3-CD1 4.36Å; W478-L481 PolarHBondContact O-N 2.58Å; W478-L482 VanDerWaalsContact CD1-CD1 3.43Å; W478-L482 HydrophobicContact CG-CD1 4.41Å; W478-L482 WeakPolarHBondContact O-CB 3.44Å; W478-L482 WeakPolarHBondContact O-CG 3.31Å; W478-L482 PolarHBondContact O-N 3.42Å
479Q76.8Confident79.7Confident143 Ų143101.1 Ų101.167%0.66853%0.529SS*.Hα-helixtrans-62.9-42.3174.9-68.6-174.3-17.700111.9K475 E476 I477 G483K475-Q479 PolarHBondContact O-N 3.06Å; E476-Q479 PolarHBondContact O-N 3.39Å; I477-Q479 VanDerWaalsContact C-N 3.29Å; I477-Q479 PolarHBondContact O-N 2.89Å; Q479-G483 PolarHBondContact O-N 2.8Å
480W82.6Confident80.6Confident211 Ų211103.6 Ų103.680%0.79954%0.539SS*.Hα-helixtrans-66.8-42.9175.4-74.9105.3000112.6I477 G483 A484I477-W480 WeakPolarHBondContact O-CB 3.35Å; I477-W480 PolarHBondContact O-N 3.31Å; I477-W480 VanDerWaalsContact O-N 3.12Å; W480-G483 PolarHBondContact O-N 2.93Å; W480-A484 WeakPolarHBondContact O-CB 3.4Å; W480-A484 PolarHBondContact O-N 3Å
481L80.6Confident81.6Confident101 Ų101100.7 Ų100.753%0.52953%0.533SS..Hα-helixtrans-63.3-42.6177.6-72175.5000112I477 W478 A484 G485I477-L481 HydrophobicContact CG2-CD1 3.73Å; I477-L481 HydrophobicContact CG2-CG 3.94Å; I477-L481 WeakPolarHBondContact O-CG 3.3Å; I477-L481 PolarHBondContact O-N 2.89Å; W478-L481 HydrophobicContact CE3-CD1 4.36Å; W478-L481 PolarHBondContact O-N 2.58Å; L481-A484 PolarHBondContact O-N 2.78Å; L481-G485 PolarHBondContact O-N 3.46Å
482L82.8Confident82.5Confident93 Ų9398.2 Ų98.249%0.48753%0.529SS..Hα-helixtrans-62.8-45.5173.9-76.6172.1000111.5W478 G485 I486W478-L482 VanDerWaalsContact CD1-CD1 3.43Å; W478-L482 HydrophobicContact CG-CD1 4.41Å; W478-L482 WeakPolarHBondContact O-CB 3.44Å; W478-L482 WeakPolarHBondContact O-CG 3.31Å; W478-L482 PolarHBondContact O-N 3.42Å; L482-G485 PolarHBondContact O-N 2.81Å; L482-I486 WeakPolarHBondContact O-CG1 3.45Å; L482-I486 PolarHBondContact O-N 3.23Å
483G82.9Confident83.3Confident39 Ų3997 Ų9740%0.40253%0.531SS..Hα-helixtrans-60-45.6176.500000112.6Q479 W480 G485 I486 L487Q479-G483 PolarHBondContact O-N 2.8Å; W480-G483 PolarHBondContact O-N 2.93Å; G483-G485 PolarHBondContact O-N 3.47Å; G483-I486 PolarHBondContact O-N 3.08Å; G483-L487 WeakPolarHBondContact O-CB 3.46Å; G483-L487 PolarHBondContact O-N 3.17Å
484A86.4Confident84.3Confident61 Ų6196.6 Ų96.650%0.50453%0.532SS..Hα-helixtrans-63.6-39.8175.700000112.1W480 L481 L487 G488W480-A484 WeakPolarHBondContact O-CB 3.4Å; W480-A484 PolarHBondContact O-N 3Å; L481-A484 PolarHBondContact O-N 2.78Å; A484-L487 PolarHBondContact O-N 2.75Å; A484-G488 PolarHBondContact O-N 3.15Å
485G87.4Confident85.3Confident45 Ų45100.9 Ų100.946%0.46454%0.541SS..Hα-helixtrans-62.6-45.3175.900000112.8L481 L482 G483 G488 A489L481-G485 PolarHBondContact O-N 3.46Å; L482-G485 PolarHBondContact O-N 2.81Å; G483-G485 PolarHBondContact O-N 3.47Å; G485-G488 PolarHBondContact O-N 2.78Å; G485-A489 WeakPolarHBondContact O-CB 3.13Å; G485-A489 PolarHBondContact O-N 2.84Å
486I91.6Very high86Confident112 Ų11296.2 Ų96.257%0.57453%0.531SS*.Hα-helixtrans-63.2-45.6176.1-67.9167.6000110.6L482 G483 G488 A489 L490L482-I486 WeakPolarHBondContact O-CG1 3.45Å; L482-I486 PolarHBondContact O-N 3.23Å; G483-I486 PolarHBondContact O-N 3.08Å; I486-G488 PolarHBondContact O-N 3.17Å; I486-A489 PolarHBondContact O-N 3.3Å; I486-L490 HydrophobicContact CG2-CD1 4.15Å; I486-L490 WeakPolarHBondContact O-CG 3.46Å; I486-L490 PolarHBondContact O-N 3.16Å
487L89.8Confident86.9Confident104 Ų10494.3 Ų94.355%0.54553%0.529SS..Hα-helixtrans-62.6-43.1178.3-174.864.1000111.7G483 A484 A489 L490 I491G483-L487 WeakPolarHBondContact O-CB 3.46Å; G483-L487 PolarHBondContact O-N 3.17Å; A484-L487 PolarHBondContact O-N 2.75Å; L487-A489 PolarHBondContact O-N 2.87Å; L487-L490 PolarHBondContact O-N 2.75Å; L487-I491 HydrophobicContact CD1-CD1 4.47Å; L487-I491 HydrophobicContact CG-CD1 4.1Å; L487-I491 VanDerWaalsContact O-CG1 3.32Å; L487-I491 WeakPolarHBondContact O-CG1 3.28Å; L487-I491 PolarHBondContact O-N 3.25Å
488G90.4Very high87.5Confident37 Ų3795.3 Ų95.338%0.38153%0.534SS..Hα-helixtrans-59.6-43.8174.300000112.5A484 G485 I486 L490 I491 A492A484-G488 PolarHBondContact O-N 3.15Å; G485-G488 PolarHBondContact O-N 2.78Å; I486-G488 PolarHBondContact O-N 3.17Å; G488-L490 PolarHBondContact O-N 3.44Å; G488-I491 PolarHBondContact O-N 3.36Å; G488-A492 WeakPolarHBondContact O-CB 3.39Å; G488-A492 PolarHBondContact O-N 2.99Å
489A89.9Confident88Confident55 Ų5590.3 Ų90.346%0.45552%0.522SS..Hα-helixtrans-64.1-38.9176.600000112.6G485 I486 L487 S493G485-A489 WeakPolarHBondContact O-CB 3.13Å; G485-A489 PolarHBondContact O-N 2.84Å; I486-A489 PolarHBondContact O-N 3.3Å; L487-A489 PolarHBondContact O-N 2.87Å; A489-S493 WeakPolarHBondContact O-CB 3.48Å; A489-S493 PolarHBondContact O-N 2.78Å; A489-S493 PolarHBondContact O-OG 2.71Å
490L92.9Very high88.6Confident99 Ų9987 Ų8752%0.51851%0.511SS..Hα-helixtrans-64.1-47.1175-76.7168.3000111.7I486 L487 G488 A492 S493 I494I486-L490 HydrophobicContact CG2-CD1 4.15Å; I486-L490 WeakPolarHBondContact O-CG 3.46Å; I486-L490 PolarHBondContact O-N 3.16Å; L487-L490 PolarHBondContact O-N 2.75Å; G488-L490 PolarHBondContact O-N 3.44Å; L490-A492 PolarHBondContact O-N 2.75Å; L490-S493 PolarHBondContact O-N 3.3Å; L490-I494 WeakPolarHBondContact O-CG1 3.31Å; L490-I494 PolarHBondContact O-N 3.31Å
491I92.4Very high88.7Confident102 Ų10283.1 Ų83.152%0.52350%0.5SS..Hα-helixtrans-61.2-46.5177.8-67.7167.6000110.5L487 G488 S493 I494 F495L487-I491 HydrophobicContact CD1-CD1 4.47Å; L487-I491 HydrophobicContact CG-CD1 4.1Å; L487-I491 VanDerWaalsContact O-CG1 3.32Å; L487-I491 WeakPolarHBondContact O-CG1 3.28Å; L487-I491 PolarHBondContact O-N 3.25Å; G488-I491 PolarHBondContact O-N 3.36Å; I491-S493 VanDerWaalsContact C-N 3.29Å; I491-S493 PolarHBondContact O-N 3.19Å; I491-I494 PolarHBondContact O-N 2.89Å; I491-F495 WeakPolarHBondContact O-CB 3.43Å; I491-F495 PolarHBondContact O-N 3.37Å
492A91Very high88.7Confident59 Ų5981 Ų8149%0.48850%0.497SS..Hα-helixtrans-60.4-40177.600000112G488 L490 F495 A496G488-A492 WeakPolarHBondContact O-CB 3.39Å; G488-A492 PolarHBondContact O-N 2.99Å; L490-A492 PolarHBondContact O-N 2.75Å; A492-F495 PolarHBondContact O-N 3.01Å; A492-A496 WeakPolarHBondContact O-CB 3.27Å; A492-A496 PolarHBondContact O-N 2.96Å
493S90.4Very high88.6Confident71 Ų7185 Ų8550%0.49751%0.506SS..Hα-helixtrans-65.2-45.1177.2-60.70000111.9A489 L490 I491 F495 A496 V497A489-S493 WeakPolarHBondContact O-CB 3.48Å; A489-S493 PolarHBondContact O-N 2.78Å; A489-S493 PolarHBondContact O-OG 2.71Å; L490-S493 PolarHBondContact O-N 3.3Å; I491-S493 VanDerWaalsContact C-N 3.29Å; I491-S493 PolarHBondContact O-N 3.19Å; S493-F495 VanDerWaalsContact C-N 3.33Å; S493-F495 PolarHBondContact O-N 2.77Å; S493-A496 PolarHBondContact O-N 2.8Å; S493-V497 VanDerWaalsContact O-CG2 3.31Å; S493-V497 WeakPolarHBondContact O-CG2 3.27Å; S493-V497 PolarHBondContact O-N 2.66Å
494I92.3Very high88.4Confident105 Ų10591.2 Ų91.254%0.53852%0.517SS..Hα-helixtrans-60.7-45.6175.3-68.5166.7000110.2L490 I491 A496 V497 L498L490-I494 WeakPolarHBondContact O-CG1 3.31Å; L490-I494 PolarHBondContact O-N 3.31Å; I491-I494 PolarHBondContact O-N 2.89Å; I494-A496 PolarHBondContact O-N 2.95Å; I494-V497 PolarHBondContact O-N 2.77Å; I494-L498 HydrophobicContact CG2-CD1 3.98Å; I494-L498 HydrophobicContact CG2-CG 4.4Å; I494-L498 WeakPolarHBondContact O-CG 3.2Å; I494-L498 PolarHBondContact O-N 2.67Å
495F92.3Very high88Confident141 Ų14196.9 Ų96.962%0.61853%0.525SS*.Hα-helixtrans-63.1-42.2179.2-151.1-90.5000111.7I491 A492 S493 V497 L498 V499I491-F495 WeakPolarHBondContact O-CB 3.43Å; I491-F495 PolarHBondContact O-N 3.37Å; A492-F495 PolarHBondContact O-N 3.01Å; S493-F495 VanDerWaalsContact C-N 3.33Å; S493-F495 PolarHBondContact O-N 2.77Å; F495-V497 PolarHBondContact O-N 3.3Å; F495-L498 PolarHBondContact O-N 2.92Å; F495-V499 HydrophobicContact CD1-CG2 3.91Å; F495-V499 HydrophobicContact CE1-CG2 3.97Å; F495-V499 WeakPolarHBondContact O-CB 3.44Å; F495-V499 VanDerWaalsContact O-CG2 3.28Å; F495-V499 WeakPolarHBondContact O-CG2 3.35Å; F495-V499 PolarHBondContact O-N 2.91Å
496A89.1Confident87.4Confident55 Ų55102.6 Ų102.646%0.45553%0.533SS..Hα-helixtrans-61-44174.900000111.8A492 S493 I494 V499 V500A492-A496 WeakPolarHBondContact O-CB 3.27Å; A492-A496 PolarHBondContact O-N 2.96Å; S493-A496 PolarHBondContact O-N 2.8Å; I494-A496 PolarHBondContact O-N 2.95Å; A496-V499 PolarHBondContact O-N 2.97Å; A496-V500 WeakPolarHBondContact O-CB 3.4Å; A496-V500 VanDerWaalsContact O-CG2 3.27Å; A496-V500 WeakPolarHBondContact O-CG2 3.39Å; A496-V500 PolarHBondContact O-N 2.86Å
497V90.4Very high86.5Confident98 Ų98104.5 Ų104.559%0.59454%0.537SS*.Hα-helixtrans-61.4-45.4175.4171.10000111S493 I494 F495 V499 V500 F501S493-V497 VanDerWaalsContact O-CG2 3.31Å; S493-V497 WeakPolarHBondContact O-CG2 3.27Å; S493-V497 PolarHBondContact O-N 2.66Å; I494-V497 PolarHBondContact O-N 2.77Å; F495-V497 PolarHBondContact O-N 3.3Å; V497-V499 PolarHBondContact O-N 3.08Å; V497-V500 PolarHBondContact O-N 3.24Å; V497-F501 WeakPolarHBondContact O-CB 3.36Å; V497-F501 PolarHBondContact O-N 3.33Å
498L89.4Confident85.5Confident105 Ų105109 Ų10955%0.5555%0.547SS..Hα-helixtrans-61.6-43177.2-72.3172.3000111.9I494 F495 F501 A502I494-L498 HydrophobicContact CG2-CD1 3.98Å; I494-L498 HydrophobicContact CG2-CG 4.4Å; I494-L498 WeakPolarHBondContact O-CG 3.2Å; I494-L498 PolarHBondContact O-N 2.67Å; F495-L498 PolarHBondContact O-N 2.92Å; L498-F501 PolarHBondContact O-N 3.09Å; L498-A502 VanDerWaalsContact O-CB 3.28Å; L498-A502 WeakPolarHBondContact O-CB 3.4Å; L498-A502 PolarHBondContact O-N 3.27Å
499V87.7Confident84.3Confident60 Ų60110.2 Ų110.236%0.36455%0.549SS..Hα-helixtrans-64.8-42.4176.4170.30000111.3F495 A496 V497 F501 A502 R503F495-V499 HydrophobicContact CD1-CG2 3.91Å; F495-V499 HydrophobicContact CE1-CG2 3.97Å; F495-V499 WeakPolarHBondContact O-CB 3.44Å; F495-V499 VanDerWaalsContact O-CG2 3.28Å; F495-V499 WeakPolarHBondContact O-CG2 3.35Å; F495-V499 PolarHBondContact O-N 2.91Å; A496-V499 PolarHBondContact O-N 2.97Å; V497-V499 PolarHBondContact O-N 3.08Å; V499-F501 VanDerWaalsContact C-N 3.34Å; V499-A502 PolarHBondContact O-N 3.49Å; V499-R503 WeakPolarHBondContact O-CB 3.2Å; V499-R503 WeakPolarHBondContact O-CG 3.4Å; V499-R503 PolarHBondContact O-N 2.75Å
500V87.9Confident83.2Confident74 Ų74112.2 Ų112.245%0.44855%0.549SS..Hα-helixtrans-63-43175.2169.40000110.6A496 V497 R503 R504A496-V500 WeakPolarHBondContact O-CB 3.4Å; A496-V500 VanDerWaalsContact O-CG2 3.27Å; A496-V500 WeakPolarHBondContact O-CG2 3.39Å; A496-V500 PolarHBondContact O-N 2.86Å; V497-V500 PolarHBondContact O-N 3.24Å; V500-R503 PolarHBondContact O-N 2.8Å; V500-R504 WeakPolarHBondContact O-CB 3.35Å; V500-R504 WeakPolarHBondContact O-CG 3.25Å; V500-R504 PolarHBondContact O-N 3.43Å
501F84.9Confident81.6Confident129 Ų129117.3 Ų117.357%0.56656%0.562SS**Hα-helixtrans-64.9-44.7178.1-151.2-91.6000111.3V497 L498 V499 R504 R505V497-F501 WeakPolarHBondContact O-CB 3.36Å; V497-F501 PolarHBondContact O-N 3.33Å; L498-F501 PolarHBondContact O-N 3.09Å; V499-F501 VanDerWaalsContact C-N 3.34Å; F501-R504 PolarHBondContact O-N 3.31Å; F501-R505 WeakPolarHBondContact O-CB 3.4Å; F501-R505 PolarHBondContact O-N 3.25Å
502A80.8Confident80Confident57 Ų57122.4 Ų122.447%0.47158%0.575SS.*Hα-helixtrans-61.4-4517500000111.8L498 V499 R504 R505 W506L498-A502 VanDerWaalsContact O-CB 3.28Å; L498-A502 WeakPolarHBondContact O-CB 3.4Å; L498-A502 PolarHBondContact O-N 3.27Å; V499-A502 PolarHBondContact O-N 3.49Å; A502-R504 PolarHBondContact O-N 2.79Å; A502-R505 PolarHBondContact O-N 2.73Å; A502-W506 WeakPolarHBondContact O-CB 3.25Å; A502-W506 PolarHBondContact O-N 3.48Å
503R81.5Confident78.3Confident176 Ų176127 Ų12766%0.66458%0.583SS**Hα-helixtrans-62.3-40.7174.6-81.3-176.7167.4178.1-1.9112.3V499 V500 W506 K507V499-R503 WeakPolarHBondContact O-CB 3.2Å; V499-R503 WeakPolarHBondContact O-CG 3.4Å; V499-R503 PolarHBondContact O-N 2.75Å; V500-R503 PolarHBondContact O-N 2.8Å; R503-W506 PolarHBondContact O-N 3.41Å; R503-K507 WeakPolarHBondContact O-CB 3.39Å; R503-K507 PolarHBondContact O-N 3.24Å
504R78.8Confident76.7Confident170 Ų170133.3 Ų133.364%0.64260%0.596SS**Hα-helixtrans-64-42.4174.3-77.1179.5178-172.80.7111.3V500 F501 A502 K507 R508V500-R504 WeakPolarHBondContact O-CB 3.35Å; V500-R504 WeakPolarHBondContact O-CG 3.25Å; V500-R504 PolarHBondContact O-N 3.43Å; F501-R504 PolarHBondContact O-N 3.31Å; A502-R504 PolarHBondContact O-N 2.79Å; R504-K507 PolarHBondContact O-N 3.28Å; R504-R508 WeakPolarHBondContact O-CB 3.31Å; R504-R508 WeakPolarHBondContact O-CG 3.45Å; R504-R508 PolarHBondContact O-N 3.04Å
505R77.1Confident74.9Confident180 Ų180131.9 Ų131.968%0.67960%0.6SS**Hα-helixtrans-65.1-41.7176.9-137.3176.3-178.3157.70.1111.5F501 A502 R508 S509F501-R505 WeakPolarHBondContact O-CB 3.4Å; F501-R505 PolarHBondContact O-N 3.25Å; A502-R505 PolarHBondContact O-N 2.73Å; R505-R508 PolarHBondContact O-N 3.34Å; R505-S509 WeakPolarHBondContact O-CB 3.33Å; R505-S509 PolarHBondContact O-N 3.14Å
506W73.9Confident72.9Confident166 Ų166130.2 Ų130.263%0.62961%0.606SS**Hα-helixtrans-65.8-45.2175.6-175.764.5000112.4A502 R503 R508 S509 Q510A502-W506 WeakPolarHBondContact O-CB 3.25Å; A502-W506 PolarHBondContact O-N 3.48Å; R503-W506 PolarHBondContact O-N 3.41Å; W506-R508 VanDerWaalsContact C-N 3.34Å; W506-R508 PolarHBondContact O-N 3Å; W506-S509 WeakPolarHBondContact O-CB 2.98Å; W506-S509 PolarHBondContact O-N 3.39Å; W506-Q510 WeakPolarHBondContact O-CB 3.39Å; W506-Q510 PolarHBondContact O-N 3.33Å
507K72.8Confident71.1Confident151 Ų151132 Ų13266%0.65762%0.615SS**Hα-helixtrans-61.4-38.2172.6-82.8-171.8175.6-176.50112.6R503 R504 R511R503-K507 WeakPolarHBondContact O-CB 3.39Å; R503-K507 PolarHBondContact O-N 3.24Å; R504-K507 PolarHBondContact O-N 3.28Å; K507-R511 PolarHBondContact O-N 3.4Å
508R69.1Low69Low199 Ų199137.9 Ų137.975%0.75163%0.628SS**Hα-helixtrans-65.8-40.5173.6-79.4-178.5177.5177.2-0.7112.1R504 R505 W506 R511 R512R504-R508 WeakPolarHBondContact O-CB 3.31Å; R504-R508 WeakPolarHBondContact O-CG 3.45Å; R504-R508 PolarHBondContact O-N 3.04Å; R505-R508 PolarHBondContact O-N 3.34Å; W506-R508 VanDerWaalsContact C-N 3.34Å; W506-R508 PolarHBondContact O-N 3Å; R508-R511 PolarHBondContact O-N 3.06Å; R508-R512 PolarHBondContact O-N 3.48Å
509S66.4Low66.7Low62 Ų62136.2 Ų136.243%0.43464%0.637SS.*Hα-helixtrans-63.3-45174.2177.30000112.1R505 W506 R512 K513R505-S509 WeakPolarHBondContact O-CB 3.33Å; R505-S509 PolarHBondContact O-N 3.14Å; W506-S509 WeakPolarHBondContact O-CB 2.98Å; W506-S509 PolarHBondContact O-N 3.39Å; S509-R512 PolarHBondContact O-N 2.82Å; S509-K513 PolarHBondContact O-N 2.94Å
510Q65.4Low64.4Low97 Ų97140.7 Ų140.745%0.45365%0.653SS.*Hα-helixtrans-60.5-43.1173.5-84.1-83.4-22.600112.5W506 K513 R514W506-Q510 WeakPolarHBondContact O-CB 3.39Å; W506-Q510 PolarHBondContact O-N 3.33Å; Q510-K513 PolarHBondContact O-N 3.32Å; Q510-R514 PolarHBondContact O-N 2.91Å
511R60.1Low62Low206 Ų206146.9 Ų146.978%0.77767%0.669SS**Hα-helixtrans-63.4-40.1173.4-86.5-175.3172176.5-2.7112.8K507 R508 R514 A515K507-R511 PolarHBondContact O-N 3.4Å; R508-R511 PolarHBondContact O-N 3.06Å; R511-R514 PolarHBondContact O-N 3.07Å; R511-A515 WeakPolarHBondContact O-CB 3.35Å; R511-A515 PolarHBondContact O-N 2.95Å
512R57.8Low59.9Low210 Ų210149.8 Ų149.879%0.79268%0.684SS**Hα-helixtrans-64.4-40.7173.8-98.1-177.7169.9173.4-3.8112.5R508 S509 A515 S516R508-R512 PolarHBondContact O-N 3.48Å; S509-R512 PolarHBondContact O-N 2.82Å; R512-A515 PolarHBondContact O-N 3.14Å; R512-S516 PolarHBondContact O-N 2.82Å
513K56.8Low58.1Low155 Ų155153.1 Ų153.167%0.67470%0.701SS**Hα-helixtrans-64-39.4173.7-83.8-172.9172.2-173.50112.5S509 Q510 S516S509-K513 PolarHBondContact O-N 2.94Å; Q510-K513 PolarHBondContact O-N 3.32Å; K513-S516 PolarHBondContact O-N 3.19Å
514R56.1Low55.8Low204 Ų204152.2 Ų152.277%0.7771%0.708SS**Hα-helixtrans-68-38.1173.9-99.7-177.6172.3-179.4-2113.3Q510 R511 S516 S517Q510-R514 PolarHBondContact O-N 2.91Å; R511-R514 PolarHBondContact O-N 3.07Å; R514-S516 VanDerWaalsContact C-N 3.32Å; R514-S516 PolarHBondContact O-N 3.21Å; R514-S517 PolarHBondContact O-N 3.05Å
515A54.8Low53.6Low75 Ų75150.9 Ų150.962%0.6271%0.713SS**Hα-helixtrans-70-27.1176.900000113.1R511 R512 S517R511-A515 WeakPolarHBondContact O-CB 3.35Å; R511-A515 PolarHBondContact O-N 2.95Å; R512-A515 PolarHBondContact O-N 3.14Å; A515-S517 VanDerWaalsContact C-N 3.28Å; A515-S517 PolarHBondContact O-N 2.83Å
516S50.7Low51.5Low106 Ų106150.2 Ų150.274%0.74172%0.718SS**THydrogen-bonded Turntrans-76.2-10.6174.1-174.60000114R512 K513 R514R512-S516 PolarHBondContact O-N 2.82Å; K513-S516 PolarHBondContact O-N 3.19Å; R514-S516 VanDerWaalsContact C-N 3.32Å; R514-S516 PolarHBondContact O-N 3.21Å
517S50Low49.5Very low92 Ų92147.1 Ų147.164%0.64372%0.721SS**THydrogen-bonded Turntrans-93.9-7.4-176.5-175.20000113.8R514 A515R514-S517 PolarHBondContact O-N 3.05Å; A515-S517 VanDerWaalsContact C-N 3.28Å; A515-S517 PolarHBondContact O-N 2.83Å
518Y47.6Very low47.6Very low222 Ų222144.4 Ų144.487%0.87172%0.721SS**  trans-121.283.7176.8-86.7-86000109.4
519G40.8Very low45.9Very low70 Ų70139.6 Ų139.672%0.72272%0.718SS**  trans-156.286170.400000109.9
520E38.6Very low44.4Very low153 Ų153144.2 Ų144.272%0.71573%0.733SS**  trans-169.4135.6141.9-112.5-168.9140.200113
521R38.5Very low43Very low204 Ų204148.3 Ų148.377%0.7775%0.752SS**  trans82.6104.9147-65.5174.9-168.6-164.46.1120.4
522Q41.2Very low41.8Very low190 Ų190141.9 Ų141.989%0.88875%0.75SS**  trans-55.4156.9146.4-77.3178.9-4800111.8
523P41.6Very low40.7Very low128 Ų128137.1 Ų137.183%0.83175%0.749SS**  -126.2166.6129.332.1-18.3000113.8
524L34.2Very low39.8Very low156 Ų156134.1 Ų134.182%0.81775%0.747SS**  trans-73.5161.4-168.8-90.7148.9000115.9
525L33Very low38.9Very low142 Ų142128.9 Ų128.974%0.74374%0.742SS**  trans74.8147156.5-63.8152.3000115.8
526Q31.8Very low38.2Very low166 Ų166134.2 Ų134.278%0.77675%0.747SS**  cis-173.2167.3-12-173.2167.910.600105.2
527S31.9Very low37.7Very low101 Ų101136.7 Ų136.771%0.70675%0.747SS**  trans87.3115.1157850000120.9
528S32.7Very low37.2Very low94 Ų94136.8 Ų136.866%0.65774%0.744SS**  77.7128.7123.365.40000120.8
529S33.2Very low36.8Very low98 Ų98131.6 Ų131.669%0.68574%0.736SS**  trans61.7146.4142.456.50000116.6
530E35.9Very low36.7Very low160 Ų160139.5 Ų139.575%0.74876%0.76SS**  cis-173.5146.6-0.2-110.7168.8170.500102.3
531E35Very low36.6Very low183 Ų183138.9 Ų138.986%0.85576%0.763SS**  trans60.8148.6138.7-64.9-171.1151.800123.1
532G35.5Very low36.5Very low71 Ų71135.4 Ų135.473%0.73276%0.762SS**  trans97.295.615100000114.5
533S34.9Very low36.3Very low109 Ų109132.4 Ų132.476%0.76276%0.755SS**  88.5136.574.91770000114.1
534S38.4Very low35.9Very low92 Ų92132.6 Ų132.664%0.64375%0.751SS**  trans63.1111.1152.953.50000117.6
535S37Very low36.1Very low94 Ų94131.2 Ų131.266%0.65775%0.747SS**  77.4154.869.482.70000114.4
536Y40.6Very low36.3Very low187 Ų187130.5 Ų130.573%0.73375%0.747SS**  trans94.8105.3178.7-63-79.4000113.9
537Q38.9Very low36.6Very low158 Ų158127.9 Ų127.974%0.73875%0.745SS**  57.5128.965.6-134.9-176.412.100107.8
538T39.2Very low36.9Very low94 Ų94130 Ų13058%0.57775%0.748SS**  -178.1152.852.3-35.40000106.9
539T39.2Very low37.3Very low114 Ų114133 Ų13370%0.69976%0.756SS**  trans42.3134.5137.854.90000120
540L39.7Very low37.7Very low236 Ų236136.2 Ų136.2100%1.23676%0.762SS**  -162.6056.6-125143.8000109.8

Retrieved 540 of 540 residues in 467.4 ms (Link to these results)