A0A087XNU7_POEFO Loading...

Potassium calcium-activated channel subfamily N member 4

AlphaFold DB , UniProt , Accession A0A087XNU7, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 513 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.2	Very low	35.9	Very low	244 Å²	244	141.1 Å²	141.1	100%	1.202	85%	0.849	S	S	*	*				0	128.4	0	-80	-104.2	-174	0	0	108
2	P	49.6	Very low	35.2	Very low	124 Å²	124	135.4 Å²	135.4	81%	0.805	84%	0.841	S	S	*	*			cis	-111.5	176.1	-11	30.2	-10.9	0	0	0	113.4
3	S	35.9	Very low	34.5	Very low	105 Å²	105	133.7 Å²	133.7	73%	0.734	84%	0.837	S	S	*	*			trans	-49.5	168.3	179.9	47.7	0	0	0	0	118.3
4	P	48.3	Very low	34.1	Very low	126 Å²	126	130.4 Å²	130.4	82%	0.818	83%	0.829	S	S	*	*				-123	151.3	126.2	31.9	-19.7	0	0	0	113.6
5	T	39.8	Very low	33.7	Very low	138 Å²	138	134.2 Å²	134.2	85%	0.847	83%	0.832	S	S	*	*			trans	-52.8	153.4	-179.7	39.4	0	0	0	0	117.2
6	R	34.4	Very low	33.4	Very low	204 Å²	204	131.6 Å²	131.6	77%	0.77	83%	0.828	S	S	*	*			trans	-84.9	144.2	171.7	173.3	-171.3	-176.3	151	3.9	111	D8	R6-D8 IonicContact NE-OD1 3.91Å; R6-D8 IonicContact NE-OD2 3.45Å; R6-D8 PolarHBondContact NE-OD2 3.38Å
7	E	31.2	Very low	33.1	Very low	187 Å²	187	134.9 Å²	134.9	87%	0.874	83%	0.831	S	S	*	*			trans	-161.7	107	145.6	-90	-172.4	172.6	0	0	104.7
8	D	32.1	Very low	32.8	Very low	127 Å²	127	135.6 Å²	135.6	68%	0.679	83%	0.834	S	S	*	*				47.5	123.6	81.9	-64.7	-27.8	0	0	0	112.2	R6	R6-D8 IonicContact NE-OD1 3.91Å; R6-D8 IonicContact NE-OD2 3.45Å; R6-D8 PolarHBondContact NE-OD2 3.38Å
9	G	29.3	Very low	32.4	Very low	74 Å²	74	132.1 Å²	132.1	76%	0.763	83%	0.828	S	S	*	*			cis	174.3	-158.9	5	0	0	0	0	0	110.2
10	A	29.1	Very low	32.1	Very low	116 Å²	116	130.7 Å²	130.7	96%	0.959	83%	0.829	S	S	*	*			trans	94.3	124.5	162.6	0	0	0	0	0	119
11	A	30.6	Very low	31.9	Very low	107 Å²	107	129 Å²	129	88%	0.884	83%	0.827	S	S	*	*			trans	-99.6	173.7	-174.6	0	0	0	0	0	112.5
12	G	27.3	Very low	31.7	Very low	73 Å²	73	123.6 Å²	123.6	75%	0.753	81%	0.811	S	S	*	*			trans	119.4	139.2	165.5	0	0	0	0	0	111.7
13	S	26.4	Very low	30.7	Very low	113 Å²	113	122.4 Å²	122.4	79%	0.79	81%	0.811	S	S	*	*			cis	173.3	151.2	-5	41.3	0	0	0	0	105.5
14	A	28.1	Very low	30.2	Very low	88 Å²	88	126.4 Å²	126.4	73%	0.727	82%	0.818	S	S	*	*			trans	68.3	152.6	160.8	0	0	0	0	0	115.9
15	Q	27.7	Very low	29.1	Very low	187 Å²	187	125 Å²	125	87%	0.874	81%	0.811	S	S	*	*			cis	-165	163.4	7	-131.7	161.7	-11.7	0	0	107.8
16	A	30.2	Very low	28.5	Very low	93 Å²	93	130.2 Å²	130.2	77%	0.769	82%	0.815	S	S	*	*			trans	-80.2	151.9	176.6	0	0	0	0	0	113.3
17	E	27.3	Very low	28	Very low	187 Å²	187	124.3 Å²	124.3	87%	0.874	82%	0.818	S	S	*	*			trans	-166.5	111.8	150.8	-105.4	-179.9	171.3	0	0	106.5
18	V	27.7	Very low	27.7	Very low	147 Å²	147	119.1 Å²	119.1	89%	0.891	82%	0.815	S	S	*	*				54.2	119.3	81.7	-175.5	0	0	0	0	113.4
19	G	25	Very low	27.3	Very low	70 Å²	70	121.3 Å²	121.3	72%	0.722	83%	0.826	S	S	*	*			trans	143	105.4	148.1	0	0	0	0	0	118.2
20	A	27.2	Very low	27.2	Very low	103 Å²	103	121.1 Å²	121.1	85%	0.851	83%	0.825	S	S	*	*			trans	76.7	110	135.3	0	0	0	0	0	120.9
21	A	27.7	Very low	27	Very low	95 Å²	95	127.6 Å²	127.6	79%	0.785	82%	0.824	S	S	*	*			trans	-67.6	164.8	149.6	0	0	0	0	0	111.7
22	P	30.9	Very low	26.9	Very low	132 Å²	132	125.9 Å²	125.9	86%	0.857	82%	0.817	S	S	*	*			trans	-125.6	145.9	138.9	33.3	-21.2	0	0	0	112
23	A	28.8	Very low	26.8	Very low	98 Å²	98	130.2 Å²	130.2	81%	0.81	82%	0.822	S	S	*	*			trans	-107.8	136.1	169.1	0	0	0	0	0	109.1
24	E	26	Very low	26.9	Very low	189 Å²	189	131.2 Å²	131.2	88%	0.883	82%	0.823	S	S	*	*			trans	-175	120.3	151.8	-104.4	-176.6	177.5	0	0	105.7
25	S	24.9	Very low	26.9	Very low	97 Å²	97	132.6 Å²	132.6	68%	0.678	83%	0.826	S	S	*	*				106.9	128.4	57.5	100	0	0	0	0	111.8
26	R	26	Very low	26.9	Very low	247 Å²	247	127.9 Å²	127.9	93%	0.932	82%	0.819	S	S	*	*			trans	73.1	113.9	158.7	-69.4	-179.3	169.1	178.6	-2	121.1
27	G	24.3	Very low	26.7	Very low	80 Å²	80	130.7 Å²	130.7	83%	0.825	82%	0.82	S	S	*	*				114.2	113.6	110.5	0	0	0	0	0	118.2
28	G	24.3	Very low	26.7	Very low	78 Å²	78	131 Å²	131	80%	0.804	82%	0.822	S	S	*	*				97.2	100.8	128.4	0	0	0	0	0	120
29	D	25.3	Very low	26.7	Very low	173 Å²	173	131.2 Å²	131.2	93%	0.925	82%	0.815	S	S	*	*			trans	79.9	138.2	136.4	-144.3	8.8	0	0	0	121
30	G	25.9	Very low	26.8	Very low	70 Å²	70	136.9 Å²	136.9	72%	0.722	82%	0.823	S	S	*	*			trans	143.4	83.9	173.2	0	0	0	0	0	115.9
31	R	26.3	Very low	26.8	Very low	253 Å²	253	139 Å²	139	96%	0.955	82%	0.819	S	S	*	*			trans	-44.8	142.7	172.3	-72.5	170	171.5	-146.8	-3.3	115.6
32	G	26.8	Very low	26.7	Very low	71 Å²	71	140.7 Å²	140.7	73%	0.732	82%	0.82	S	S	*	*			trans	-172.1	100.5	159.4	0	0	0	0	0	112.1	V34	G32-V34 PolarHBondContact O-N 2.93Å
33	L	26.5	Very low	26.5	Very low	163 Å²	163	142.1 Å²	142.1	85%	0.853	82%	0.82	S	S	*	*			trans	-49.7	126.5	-177	-100.5	77	0	0	0	114.1
34	V	28.2	Very low	26.4	Very low	135 Å²	135	148.4 Å²	148.4	82%	0.818	82%	0.823	S	S	*	*			trans	-125.1	104.3	154.7	175.8	0	0	0	0	107	G32 A36	G32-V34 PolarHBondContact O-N 2.93Å; V34-A36 PolarHBondContact O-N 3.45Å
35	C	27.7	Very low	26.6	Very low	116 Å²	116	144.2 Å²	144.2	78%	0.784	81%	0.814	S	S	*	*			trans	-79.4	92.1	170.1	-78.7	0	0	0	0	109.3
36	A	27	Very low	26.7	Very low	89 Å²	89	147.6 Å²	147.6	74%	0.736	82%	0.824	S	S	*	*			trans	-89	124.5	151.5	0	0	0	0	0	107.3	V34	V34-A36 PolarHBondContact O-N 3.45Å
37	L	27.7	Very low	26.7	Very low	151 Å²	151	141.6 Å²	141.6	79%	0.791	82%	0.82	S	S	*	*			trans	-118.4	79.1	171.2	-133.7	141.4	0	0	0	107.2	M39	L37-M39 HydrophobicContact CD2-CB 4.26Å
38	E	26.5	Very low	26.7	Very low	193 Å²	193	142.2 Å²	142.2	90%	0.902	81%	0.812	S	S	*	*			trans	-76.5	120.2	150.2	-99.3	178.8	154.7	0	0	106.6
39	M	27.1	Very low	26.9	Very low	152 Å²	152	147.2 Å²	147.2	75%	0.749	81%	0.811	S	S	*	*			trans	-118.1	92.7	167	-152	175.3	-175.6	0	0	107.6	L37 L41	L37-M39 HydrophobicContact CD2-CB 4.26Å; M39-L41 PolarHBondContact O-N 3.16Å
40	E	27.2	Very low	26.9	Very low	190 Å²	190	147.6 Å²	147.6	89%	0.888	81%	0.809	S	S	*	*			trans	-70.1	112.1	167	-160.4	166.3	-161.1	0	0	107.2
41	L	27.3	Very low	26.9	Very low	147 Å²	147	150.4 Å²	150.4	77%	0.77	81%	0.808	S	S	*	*			trans	-106.3	108.7	178.6	-129.7	144.5	0	0	0	109	M39	M39-L41 PolarHBondContact O-N 3.16Å
42	T	26.9	Very low	26.8	Very low	130 Å²	130	144.8 Å²	144.8	80%	0.798	81%	0.806	S	S	*	*			trans	-57.5	126.2	-175.6	-19.3	0	0	0	0	111.2	R44	T42-R44 PolarHBondContact O-N 3.26Å
43	N	26.8	Very low	26.8	Very low	162 Å²	162	147.4 Å²	147.4	87%	0.866	81%	0.807	S	S	*	*			trans	-80.1	109.1	178.5	-150.9	5.2	0	0	0	109.1
44	R	25.7	Very low	26.9	Very low	231 Å²	231	144.7 Å²	144.7	87%	0.872	80%	0.802	S	S	*	*			trans	-125.1	105.7	162	-93.8	-170.9	175.6	-176.3	-0.4	109.4	T42	T42-R44 PolarHBondContact O-N 3.26Å
45	S	30.1	Very low	26.7	Very low	100 Å²	100	144.4 Å²	144.4	70%	0.699	81%	0.805	S	S	*	*			trans	17.6	112.5	149.4	60.1	0	0	0	0	117.8
46	L	26.1	Very low	26.7	Very low	168 Å²	168	146 Å²	146	88%	0.88	81%	0.806	S	S	*	*			trans	-142.7	102.5	138.8	-136.5	86.1	0	0	0	109.3
47	S	26.3	Very low	26.7	Very low	122 Å²	122	150 Å²	150	85%	0.853	81%	0.809	S	S	*	*			trans	-87	115.8	162.5	152.6	0	0	0	0	107.2
48	S	25.1	Very low	26.7	Very low	93 Å²	93	150.2 Å²	150.2	65%	0.65	81%	0.81	S	S	*	*			trans	-159.3	120.6	145.4	57.3	0	0	0	0	110
49	K	28.3	Very low	26.8	Very low	183 Å²	183	148.3 Å²	148.3	80%	0.796	80%	0.804	S	S	*	*			trans	-39	136.2	159	-86.8	171	159.9	-178.9	0	110.9
50	M	26	Very low	26.8	Very low	180 Å²	180	147.2 Å²	147.2	89%	0.887	80%	0.802	S	S	*	*			trans	-132.3	97.6	159.7	-153.2	110.1	165.3	0	0	107
51	D	25.8	Very low	26.8	Very low	129 Å²	129	150.1 Å²	150.1	69%	0.69	81%	0.805	S	S	*	*			trans	-71.1	130.8	171	-68.9	-46	0	0	0	108.5	V53	D51-V53 PolarHBondContact O-N 2.99Å
52	C	24.2	Very low	26.8	Very low	135 Å²	135	150 Å²	150	91%	0.912	81%	0.805	S	S	*	*			trans	-77.8	113.3	171.5	-75.1	0	0	0	0	109
53	V	27	Very low	26.8	Very low	126 Å²	126	149.9 Å²	149.9	76%	0.764	81%	0.808	S	S	*	*			trans	-121.7	117.9	168.6	176.9	0	0	0	0	109.1	D51	D51-V53 PolarHBondContact O-N 2.99Å
54	S	27.3	Very low	26.9	Very low	106 Å²	106	146.9 Å²	146.9	74%	0.741	81%	0.806	S	S	*	*			trans	16.1	116.2	151.2	-153.9	0	0	0	0	118.2
55	C	25.3	Very low	27.1	Very low	130 Å²	130	143.1 Å²	143.1	88%	0.878	80%	0.803	S	S	*	*			trans	-97.1	104.2	156.9	-68.1	0	0	0	0	108.8
56	D	26.8	Very low	27	Very low	150 Å²	150	144 Å²	144	80%	0.802	81%	0.809	S	S	*	*			trans	-146.6	148.2	153.3	-113.5	-22	0	0	0	108.5
57	E	27.4	Very low	27.4	Very low	172 Å²	172	141.4 Å²	141.4	80%	0.804	80%	0.802	S	S	*	*			trans	70.5	109.5	175.4	-79.6	-176.3	142.5	0	0	118.8
58	L	27.3	Very low	27.4	Very low	156 Å²	156	144.5 Å²	144.5	82%	0.817	80%	0.803	S	S	*	*				160.4	136.9	87.3	-115.8	149.1	0	0	0	111.6
59	I	29.3	Very low	27.5	Very low	152 Å²	152	146 Å²	146	78%	0.779	81%	0.808	S	S	*	*			trans	-79.6	150.5	-175.6	-70	158.9	0	0	0	111.3
60	N	27	Very low	27.4	Very low	129 Å²	129	142.9 Å²	142.9	69%	0.69	81%	0.809	S	S	*	*			trans	81.7	115.5	155.8	-111.2	-3.1	0	0	0	120.3
61	R	27.5	Very low	27.5	Very low	252 Å²	252	139.7 Å²	139.7	95%	0.951	80%	0.8	S	S	*	*				-164.5	141.1	120.9	-111.3	172.9	173.6	169.6	-1.5	112.7
62	N	27.5	Very low	27.6	Very low	145 Å²	145	139.3 Å²	139.3	78%	0.775	80%	0.804	S	S	*	*			trans	-85	161	-170.4	-75.3	-30.8	0	0	0	115.1
63	C	26.2	Very low	27.8	Very low	126 Å²	126	140.5 Å²	140.5	85%	0.851	80%	0.801	S	S	*	*			trans	82.7	114.5	141	-123.4	0	0	0	0	120.4
64	A	29.2	Very low	27.9	Very low	100 Å²	100	139.5 Å²	139.5	83%	0.826	80%	0.799	S	S	*	*				179.6	147.3	109.4	0	0	0	0	0	112.1
65	D	28.6	Very low	28	Very low	151 Å²	151	139.1 Å²	139.1	81%	0.807	80%	0.803	S	S	*	*			trans	-69	147.7	-166.7	-61.1	-58	0	0	0	117.3
66	S	28.3	Very low	28.4	Very low	118 Å²	118	140.1 Å²	140.1	83%	0.825	80%	0.799	S	S	*	*				-179.8	151.2	120.6	-78.7	0	0	0	0	112
67	P	34.8	Very low	28.8	Very low	115 Å²	115	135.5 Å²	135.5	75%	0.747	79%	0.787	S	S	*	*			trans	-94.7	139.6	-164.8	35.8	-29	0	0	0	111.5
68	E	26.8	Very low	29.3	Very low	186 Å²	186	137.4 Å²	137.4	87%	0.869	79%	0.792	S	S	*	*			trans	-176.3	132.5	139.7	-107.1	172.9	173.9	0	0	114.6
69	V	27.9	Very low	29.7	Very low	125 Å²	125	140.6 Å²	140.6	76%	0.758	79%	0.793	S	S	*	*			trans	62.4	90.5	154.8	-165.5	0	0	0	0	118.3
70	S	25.1	Very low	30.2	Very low	118 Å²	118	138.9 Å²	138.9	83%	0.825	79%	0.789	S	S	*	*			trans	-76.2	112.9	161.4	53.1	0	0	0	0	111.7
71	V	28.5	Very low	31	Very low	112 Å²	112	135.5 Å²	135.5	68%	0.679	77%	0.774	S	S	*	*			trans	-95.4	125.7	153.5	179.8	0	0	0	0	106.6	L73	V71-L73 PolarHBondContact O-N 3.44Å
72	P	26.7	Very low	32	Very low	122 Å²	122	130.9 Å²	130.9	79%	0.792	76%	0.762	S	S	*	*			trans	-76.3	91	-179.5	30.6	-30.2	0	0	0	108.8	S74	P72-S74 PolarHBondContact O-N 2.93Å; P72-S74 VanDerWaalsContact O-N 3.17Å
73	L	30.3	Very low	33.2	Very low	159 Å²	159	131 Å²	131	83%	0.832	76%	0.76	S	S	*	*			trans	-69.2	105.8	151.9	-107.6	108.3	0	0	0	106.1	V71 A75	V71-L73 PolarHBondContact O-N 3.44Å; L73-A75 PolarHBondContact O-N 3.23Å; L73-A75 VanDerWaalsContact O-N 3.14Å
74	S	28	Very low	34.8	Very low	105 Å²	105	131.1 Å²	131.1	73%	0.734	75%	0.748	S	S	*	*			trans	-35.2	121.2	165	51.2	0	0	0	0	109.6	P72 L76	P72-S74 PolarHBondContact O-N 2.93Å; P72-S74 VanDerWaalsContact O-N 3.17Å; S74-L76 PolarHBondContact O-N 2.9Å
75	A	29.6	Very low	36.9	Very low	99 Å²	99	128 Å²	128	82%	0.818	73%	0.726	S	S	*	*			trans	-42.9	105.2	173.8	0	0	0	0	0	109.2	L73 G77	L73-A75 PolarHBondContact O-N 3.23Å; L73-A75 VanDerWaalsContact O-N 3.14Å; A75-G77 PolarHBondContact O-N 3.35Å
76	L	33.5	Very low	39.2	Very low	151 Å²	151	124.6 Å²	124.6	79%	0.791	71%	0.708	S	S	*	*			trans	-65.3	93	165	-176.9	66.6	0	0	0	104.6	S74 K78	S74-L76 PolarHBondContact O-N 2.9Å; L76-K78 PolarHBondContact O-N 3.24Å
77	G	34.8	Very low	41.7	Very low	53 Å²	53	121.9 Å²	121.9	55%	0.546	68%	0.684	S	S	.	*			trans	-44.6	114.7	171.1	0	0	0	0	0	107.6	A75 R79	A75-G77 PolarHBondContact O-N 3.35Å; G77-R79 PolarHBondContact O-N 2.9Å
78	K	38.1	Very low	44	Very low	211 Å²	211	121.5 Å²	121.5	92%	0.917	68%	0.675	S	S	*	*	S	Bend	trans	-53.4	76.4	164.6	-77.9	174.3	169.5	176.6	0	109.1	L76	L76-K78 PolarHBondContact O-N 3.24Å
79	R	36.6	Very low	46.7	Very low	224 Å²	224	116.2 Å²	116.2	85%	0.845	66%	0.658	S	S	*	*			trans	-172.9	38.6	169.6	-135.6	-179.9	-71.9	-157	0.1	111.8	G77 T81	G77-R79 PolarHBondContact O-N 2.9Å; R79-T81 PolarHBondContact O-N 3.45Å
80	V	39.5	Very low	49.4	Very low	115 Å²	115	113.3 Å²	113.3	70%	0.697	63%	0.633	S	S	*	*	S	Bend	trans	-70.7	77.4	148.1	-178.3	0	0	0	0	105.5
81	T	44.6	Very low	52.2	Low	58 Å²	58	112.6 Å²	112.6	36%	0.356	62%	0.62	S	S	.	*			trans	38.2	88	153	47	0	0	0	0	115.5	R79 M83 E84 G85	R79-T81 PolarHBondContact O-N 3.45Å; T81-M83 PolarHBondContact O-N 3.42Å; T81-E84 WeakPolarHBondContact O-CB 3.46Å; T81-E84 PolarHBondContact O-N 2.95Å; T81-E84 WeakPolarHBondContact OG1-CB 3.37Å; T81-E84 PolarHBondContact OG1-OE2 2.95Å; T81-G85 PolarHBondContact O-N 2.7Å
82	H	48.3	Very low	55	Low	155 Å²	155	112.2 Å²	112.2	72%	0.718	61%	0.613	S	S	*	*	H	α-helix	trans	-45.3	-36.1	163.5	-170.9	-70	0	0	0	111.8	E84 G85 D86	H82-E84 VanDerWaalsContact C-N 3.35Å; H82-E84 PolarHBondContact O-N 3.34Å; H82-G85 PolarHBondContact O-N 3.45Å; H82-D86 IonicContact CE1-OD1 2.77Å; H82-D86 IonicContact CE1-OD2 3.95Å; H82-D86 PolarHBondContact CE1-OD2 3.41Å; H82-D86 IonicContact ND1-OD1 3.53Å; H82-D86 IonicContact ND1-OD2 3.37Å; H82-D86 PolarHBondContact ND1-OD2 3.35Å; H82-D86 VanDerWaalsContact O-CG 3.26Å; H82-D86 PolarHBondContact O-N 2.92Å
83	M	52.1	Low	57.8	Low	147 Å²	147	110.7 Å²	110.7	72%	0.724	60%	0.598	S	S	*	*	H	α-helix	trans	-63.5	-30	174.5	-70.9	-176.8	75.8	0	0	115	T81 D87	T81-M83 PolarHBondContact O-N 3.42Å; M83-D87 PolarHBondContact O-N 2.95Å
84	E	59.8	Low	60.5	Low	130 Å²	130	106.5 Å²	106.5	61%	0.607	57%	0.571	S	S	*	*	H	α-helix	trans	-83.8	-30.9	-177.3	-159.2	163.2	-178.7	0	0	111.3	T81 H82 L88	T81-E84 WeakPolarHBondContact O-CB 3.46Å; T81-E84 PolarHBondContact O-N 2.95Å; T81-E84 WeakPolarHBondContact OG1-CB 3.37Å; T81-E84 PolarHBondContact OG1-OE2 2.95Å; H82-E84 VanDerWaalsContact C-N 3.35Å; H82-E84 PolarHBondContact O-N 3.34Å; E84-L88 PolarHBondContact O-N 2.86Å; E84-L88 VanDerWaalsContact O-N 3.15Å
85	G	72.8	Confident	63.2	Low	35 Å²	35	109.2 Å²	109.2	36%	0.361	57%	0.57	S	S	.	*	H	α-helix	trans	-66.5	-44.4	169.2	0	0	0	0	0	112.7	T81 H82 D87 L88 C89	T81-G85 PolarHBondContact O-N 2.7Å; H82-G85 PolarHBondContact O-N 3.45Å; G85-D87 VanDerWaalsContact C-N 3.32Å; G85-D87 PolarHBondContact O-N 2.86Å; G85-L88 PolarHBondContact O-N 3.48Å; G85-C89 PolarHBondContact O-N 3.24Å; G85-C89 PolarHBondContact O-SG 3.42Å
86	D	77.6	Confident	66	Low	79 Å²	79	110.6 Å²	110.6	42%	0.422	56%	0.558	S	S	.	*	H	α-helix	trans	-61.5	-41.1	177.7	-67.8	-29.2	0	0	0	111.6	H82 R90	H82-D86 IonicContact CE1-OD1 2.77Å; H82-D86 IonicContact CE1-OD2 3.95Å; H82-D86 PolarHBondContact CE1-OD2 3.41Å; H82-D86 IonicContact ND1-OD1 3.53Å; H82-D86 IonicContact ND1-OD2 3.37Å; H82-D86 PolarHBondContact ND1-OD2 3.35Å; H82-D86 VanDerWaalsContact O-CG 3.26Å; H82-D86 PolarHBondContact O-N 2.92Å; D86-R90 WeakPolarHBondContact O-CD 3.36Å; D86-R90 WeakPolarHBondContact O-CG 3.43Å; D86-R90 PolarHBondContact O-N 2.86Å; D86-R90 VanDerWaalsContact O-N 3.1Å
87	D	80.6	Confident	68.6	Low	61 Å²	61	104.4 Å²	104.4	33%	0.326	53%	0.525	S	S	.	.	H	α-helix	trans	-69.3	-34.7	178	-79	-6.4	0	0	0	112.8	M83 G85 R90 L91 K171	M83-D87 PolarHBondContact O-N 2.95Å; G85-D87 VanDerWaalsContact C-N 3.32Å; G85-D87 PolarHBondContact O-N 2.86Å; D87-R90 PolarHBondContact O-N 3.29Å; D87-L91 WeakPolarHBondContact O-CG 3.32Å; D87-L91 PolarHBondContact O-N 2.94Å; D87-L91 VanDerWaalsContact O-N 3.11Å; D87-K171 WeakPolarHBondContact OD1-CE 3.02Å; D87-K171 IonicContact OD1-NZ 2.61Å; D87-K171 PolarHBondContact OD1-NZ 3.44Å; D87-K171 IonicContact OD2-NZ 2.84Å; D87-K171 PolarHBondContact OD2-NZ 2.93Å
88	L	83.6	Confident	71.1	Confident	106 Å²	106	102.6 Å²	102.6	56%	0.555	50%	0.503	S	S	*	.	H	α-helix	trans	-68.5	-45.2	174.7	-172.5	64.1	0	0	0	112.1	E84 G85 R90 L91 I92	E84-L88 PolarHBondContact O-N 2.86Å; E84-L88 VanDerWaalsContact O-N 3.15Å; G85-L88 PolarHBondContact O-N 3.48Å; L88-R90 VanDerWaalsContact C-N 3.25Å; L88-R90 PolarHBondContact O-N 3.33Å; L88-L91 PolarHBondContact O-N 2.88Å; L88-L91 VanDerWaalsContact O-N 3.14Å; L88-I92 HydrophobicContact CG-CD1 4.42Å; L88-I92 WeakPolarHBondContact O-CG1 3.41Å; L88-I92 PolarHBondContact O-N 3.48Å
89	C	83.7	Confident	73.4	Confident	75 Å²	75	95.6 Å²	95.6	51%	0.507	47%	0.473	S	S	.	.	H	α-helix	trans	-56.3	-42	174.7	-74.4	0	0	0	0	111.3	G85 L91 I92 D93	G85-C89 PolarHBondContact O-N 3.24Å; G85-C89 PolarHBondContact O-SG 3.42Å; C89-L91 PolarHBondContact O-N 3.18Å; C89-I92 WeakPolarHBondContact O-CB 3.48Å; C89-I92 PolarHBondContact O-N 2.89Å; C89-D93 PolarHBondContact O-N 3.42Å
90	R	84.1	Confident	76	Confident	64 Å²	64	86.3 Å²	86.3	24%	0.242	44%	0.44	C	S	.	.	H	α-helix	trans	-64.7	-38.3	176.6	-70.7	171	69.3	149.8	13.1	113.5	D86 D87 L88 I92 D93 R94 I168 K171	D86-R90 WeakPolarHBondContact O-CD 3.36Å; D86-R90 WeakPolarHBondContact O-CG 3.43Å; D86-R90 PolarHBondContact O-N 2.86Å; D86-R90 VanDerWaalsContact O-N 3.1Å; D87-R90 PolarHBondContact O-N 3.29Å; L88-R90 VanDerWaalsContact C-N 3.25Å; L88-R90 PolarHBondContact O-N 3.33Å; R90-I92 VanDerWaalsContact C-N 3.29Å; R90-D93 PolarHBondContact O-N 2.97Å; R90-R94 WeakPolarHBondContact O-CB 3.27Å; R90-R94 PolarHBondContact O-N 2.9Å; R90-I168 HydrophobicContact CB-CG2 4.43Å; R90-I168 PolarHBondContact NH2-O 3.25Å; R90-K171 VanDerWaalsContact NH2-CG 3.31Å
91	L	83.5	Confident	78.4	Confident	103 Å²	103	81.5 Å²	81.5	54%	0.539	41%	0.41	S	S	.	.	H	α-helix	trans	-65.7	-35.3	175.6	-72	171.1	0	0	0	111.6	D87 L88 C89 K95	D87-L91 WeakPolarHBondContact O-CG 3.32Å; D87-L91 PolarHBondContact O-N 2.94Å; D87-L91 VanDerWaalsContact O-N 3.11Å; L88-L91 PolarHBondContact O-N 2.88Å; L88-L91 VanDerWaalsContact O-N 3.14Å; C89-L91 PolarHBondContact O-N 3.18Å; L91-K95 PolarHBondContact O-N 3.34Å; L91-K95 VanDerWaalsContact O-N 3.07Å
92	I	86.5	Confident	80.6	Confident	104 Å²	104	81 Å²	81	53%	0.533	40%	0.403	S	S	.	.	H	α-helix	trans	-66.5	-49.5	174.4	-65.1	167.2	0	0	0	110.4	L88 C89 R90 R94 K95 F96	L88-I92 HydrophobicContact CG-CD1 4.42Å; L88-I92 WeakPolarHBondContact O-CG1 3.41Å; L88-I92 PolarHBondContact O-N 3.48Å; C89-I92 WeakPolarHBondContact O-CB 3.48Å; C89-I92 PolarHBondContact O-N 2.89Å; R90-I92 VanDerWaalsContact C-N 3.29Å; I92-R94 VanDerWaalsContact C-N 3.31Å; I92-R94 PolarHBondContact O-N 3.3Å; I92-K95 WeakPolarHBondContact O-CB 3.32Å; I92-K95 PolarHBondContact O-N 2.95Å; I92-K95 VanDerWaalsContact O-N 3.11Å; I92-F96 PolarHBondContact O-N 3.3Å
93	D	86.1	Confident	82.7	Confident	91 Å²	91	81.1 Å²	81.1	49%	0.487	40%	0.397	S	S	.	.	H	α-helix	trans	-59.1	-42.8	177	-76.5	-16.5	0	0	0	111.9	C89 R90 K95 F96 L97	C89-D93 PolarHBondContact O-N 3.42Å; R90-D93 PolarHBondContact O-N 2.97Å; D93-K95 VanDerWaalsContact C-N 3.33Å; D93-K95 PolarHBondContact O-N 3.46Å; D93-F96 PolarHBondContact O-N 2.81Å; D93-L97 WeakPolarHBondContact O-CB 3.49Å; D93-L97 WeakPolarHBondContact O-CG 3.29Å; D93-L97 PolarHBondContact O-N 3.26Å
94	R	86.6	Confident	84.7	Confident	70 Å²	70	75.5 Å²	75.5	26%	0.264	37%	0.37	S	S	.	.	H	α-helix	trans	-58.2	-44.4	175.2	-171.1	-171.6	-169.8	-146.9	3.3	111.7	R90 I92 L97 I98 L165 D169	R90-R94 WeakPolarHBondContact O-CB 3.27Å; R90-R94 PolarHBondContact O-N 2.9Å; I92-R94 VanDerWaalsContact C-N 3.31Å; I92-R94 PolarHBondContact O-N 3.3Å; R94-L97 PolarHBondContact O-N 3.49Å; R94-I98 HydrophobicContact CG-CD1 4.14Å; R94-I98 WeakPolarHBondContact O-CD1 3.5Å; R94-I98 VanDerWaalsContact O-CG1 3.23Å; R94-I98 WeakPolarHBondContact O-CG1 3.32Å; R94-I98 PolarHBondContact O-N 3.04Å; R94-L165 HydrophobicContact CB-CD1 4.44Å; R94-L165 HydrophobicContact CG-CD1 3.58Å; R94-D169 IonicContact CZ-OD1 2.86Å; R94-D169 IonicContact CZ-OD2 3.33Å; R94-D169 IonicContact NE-OD1 3.38Å; R94-D169 PolarHBondContact NE-OD1 2.95Å; R94-D169 IonicContact NE-OD2 3.53Å; R94-D169 IonicContact NH2-OD1 3.63Å; R94-D169 PolarHBondContact NH2-OD1 3.26Å; R94-D169 IonicContact NH2-OD2 2.91Å; R94-D169 PolarHBondContact NH2-OD2 3.28Å; R94-D169 VanDerWaalsContact NH2-OD2 3.14Å
95	K	85.5	Confident	86.3	Confident	162 Å²	162	69.4 Å²	69.4	70%	0.704	34%	0.342	S	S	*	.	H	α-helix	trans	-63	-43.8	177.5	-177	-176.9	176	-174.1	0	111.1	L91 I92 D93 I98 E99	L91-K95 PolarHBondContact O-N 3.34Å; L91-K95 VanDerWaalsContact O-N 3.07Å; I92-K95 WeakPolarHBondContact O-CB 3.32Å; I92-K95 PolarHBondContact O-N 2.95Å; I92-K95 VanDerWaalsContact O-N 3.11Å; D93-K95 VanDerWaalsContact C-N 3.33Å; D93-K95 PolarHBondContact O-N 3.46Å; K95-I98 PolarHBondContact O-N 2.97Å; K95-E99 PolarHBondContact O-N 3.03Å; K95-E99 VanDerWaalsContact O-N 3.14Å
96	F	88.9	Confident	87.3	Confident	129 Å²	129	69.7 Å²	69.7	57%	0.566	34%	0.341	S	S	*	.	H	α-helix	trans	-62.7	-46.4	177.6	-173	-95.6	0	0	0	111.7	I92 D93 I98 E99 D100	I92-F96 PolarHBondContact O-N 3.3Å; D93-F96 PolarHBondContact O-N 2.81Å; F96-I98 VanDerWaalsContact C-N 3.29Å; F96-I98 PolarHBondContact O-N 3.35Å; F96-E99 PolarHBondContact O-N 2.94Å; F96-E99 VanDerWaalsContact O-N 3.14Å; F96-D100 WeakPolarHBondContact CE1-OD2 3.33Å; F96-D100 PolarHBondContact O-N 3.43Å
97	L	88.2	Confident	88.1	Confident	20 Å²	20	70.9 Å²	70.9	11%	0.105	35%	0.346	C	S	.	.	H	α-helix	trans	-60.2	-36.5	176.9	-74.1	169.3	0	0	0	113	D93 R94 K101 K161 L165 I168	D93-L97 WeakPolarHBondContact O-CB 3.49Å; D93-L97 WeakPolarHBondContact O-CG 3.29Å; D93-L97 PolarHBondContact O-N 3.26Å; R94-L97 PolarHBondContact O-N 3.49Å; L97-K101 WeakPolarHBondContact O-CB 3.47Å; L97-K101 VanDerWaalsContact O-CG 3.26Å; L97-K101 WeakPolarHBondContact O-CG 3.4Å; L97-K101 PolarHBondContact O-N 3.46Å; L97-K161 HydrophobicContact CD2-CD 3.52Å; L97-L165 HydrophobicContact CB-CD1 4.18Å; L97-L165 HydrophobicContact CD1-CD1 4.49Å; L97-I168 HydrophobicContact CD1-CD1 3.24Å
98	I	85.8	Confident	88.8	Confident	15 Å²	15	68.1 Å²	68.1	8%	0.077	33%	0.332	C	S	.	.	H	α-helix	trans	-67	-42.3	175.9	-71.2	164.2	0	0	0	111.1	R94 K95 F96 K101 K102 L165 L257 R262	R94-I98 HydrophobicContact CG-CD1 4.14Å; R94-I98 WeakPolarHBondContact O-CD1 3.5Å; R94-I98 VanDerWaalsContact O-CG1 3.23Å; R94-I98 WeakPolarHBondContact O-CG1 3.32Å; R94-I98 PolarHBondContact O-N 3.04Å; K95-I98 PolarHBondContact O-N 2.97Å; F96-I98 VanDerWaalsContact C-N 3.29Å; F96-I98 PolarHBondContact O-N 3.35Å; I98-K101 PolarHBondContact O-N 3.08Å; I98-K102 PolarHBondContact O-N 3.35Å; I98-K102 VanDerWaalsContact O-N 3.08Å; I98-L165 HydrophobicContact CD1-CD1 4.47Å; I98-L165 HydrophobicContact CG1-CD1 4.08Å; I98-L165 HydrophobicContact CG1-CD2 4.17Å; I98-L257 HydrophobicContact CG2-CD1 3.38Å; I98-L257 HydrophobicContact CG2-CD2 4.12Å; I98-L257 HydrophobicContact CG2-CG 3.7Å; I98-R262 VanDerWaalsContact CD1-NH1 3.33Å
99	E	88.1	Confident	89.4	Confident	64 Å²	64	64.7 Å²	64.7	30%	0.299	31%	0.314	S	S	.	.	H	α-helix	trans	-67.4	-39.9	177.1	-167.1	63	-147.2	0	0	111.4	K95 F96 K102 R103	K95-E99 PolarHBondContact O-N 3.03Å; K95-E99 VanDerWaalsContact O-N 3.14Å; F96-E99 PolarHBondContact O-N 2.94Å; F96-E99 VanDerWaalsContact O-N 3.14Å; E99-K102 WeakPolarHBondContact O-CB 3.48Å; E99-K102 PolarHBondContact O-N 2.82Å; E99-K102 IonicContact OE1-NZ 3.14Å; E99-K102 PolarHBondContact OE1-NZ 3.44Å; E99-K102 IonicContact OE2-NZ 3.48Å; E99-R103 WeakPolarHBondContact O-CG 3.34Å; E99-R103 PolarHBondContact O-N 2.88Å
100	D	90.4	Very high	89.9	Confident	29 Å²	29	62.8 Å²	62.8	16%	0.155	31%	0.307	C	S	.	.	H	α-helix	trans	-58.8	-46.7	172.3	-86.6	-1.3	0	0	0	111.8	F96 K102 R103 L104 K161	F96-D100 WeakPolarHBondContact CE1-OD2 3.33Å; F96-D100 PolarHBondContact O-N 3.43Å; D100-K102 VanDerWaalsContact C-N 3.26Å; D100-K102 PolarHBondContact O-N 3.07Å; D100-R103 PolarHBondContact O-N 3.32Å; D100-L104 WeakPolarHBondContact O-CG 3.45Å; D100-L104 PolarHBondContact O-N 2.92Å; D100-K161 IonicContact OD2-NZ 2.66Å; D100-K161 PolarHBondContact OD2-NZ 2.86Å
101	K	90.1	Very high	90.4	Very high	15 Å²	15	61.1 Å²	61.1	7%	0.065	30%	0.304	C	S	.	.	H	α-helix	trans	-59.3	-39.2	177	-77.3	175.8	76.2	-178	0	111.8	L97 I98 L104 C105 F158 K161 D162 L165 L251	L97-K101 WeakPolarHBondContact O-CB 3.47Å; L97-K101 VanDerWaalsContact O-CG 3.26Å; L97-K101 WeakPolarHBondContact O-CG 3.4Å; L97-K101 PolarHBondContact O-N 3.46Å; I98-K101 PolarHBondContact O-N 3.08Å; K101-L104 PolarHBondContact O-N 2.9Å; K101-C105 VanDerWaalsContact O-CB 3.29Å; K101-C105 WeakPolarHBondContact O-CB 3.49Å; K101-C105 PolarHBondContact O-N 3.03Å; K101-F158 HydrophobicContact CB-CD2 4.44Å; K101-F158 HydrophobicContact CB-CE2 4.25Å; K101-K161 HydrophobicContact CD-CB 4.18Å; K101-K161 HydrophobicContact CG-CB 3.62Å; K101-D162 IonicContact NZ-OD1 2.69Å; K101-D162 PolarHBondContact NZ-OD1 3.33Å; K101-L165 HydrophobicContact CD-CD2 4.38Å; K101-L251 HydrophobicContact CB-CD2 4.21Å; K101-L251 WeakPolarHBondContact O-CD2 3.34Å
102	K	90.2	Very high	90.9	Very high	47 Å²	47	56.3 Å²	56.3	20%	0.204	28%	0.279	C	S	.	.	H	α-helix	trans	-64.1	-45.4	176.2	178.3	-178.7	154	-141.2	0	111.2	I98 E99 D100 C105 A106 L251	I98-K102 PolarHBondContact O-N 3.35Å; I98-K102 VanDerWaalsContact O-N 3.08Å; E99-K102 WeakPolarHBondContact O-CB 3.48Å; E99-K102 PolarHBondContact O-N 2.82Å; E99-K102 IonicContact OE1-NZ 3.14Å; E99-K102 PolarHBondContact OE1-NZ 3.44Å; E99-K102 IonicContact OE2-NZ 3.48Å; D100-K102 VanDerWaalsContact C-N 3.26Å; D100-K102 PolarHBondContact O-N 3.07Å; K102-C105 PolarHBondContact O-N 3.48Å; K102-A106 PolarHBondContact O-N 2.68Å; K102-L251 HydrophobicContact CB-CD2 4.32Å; K102-L251 HydrophobicContact CB-CG 4.19Å
103	R	91.9	Very high	91.3	Very high	157 Å²	157	55.3 Å²	55.3	59%	0.592	27%	0.274	S	S	*	.	H	α-helix	trans	-60.9	-47.1	174.8	-69.1	176.1	-178.8	-158.9	0.2	111.9	E99 D100 C105 A106 L107	E99-R103 WeakPolarHBondContact O-CG 3.34Å; E99-R103 PolarHBondContact O-N 2.88Å; D100-R103 PolarHBondContact O-N 3.32Å; R103-C105 VanDerWaalsContact C-N 3.33Å; R103-C105 PolarHBondContact O-N 3.01Å; R103-A106 PolarHBondContact O-N 2.86Å; R103-L107 WeakPolarHBondContact O-CG 3.42Å; R103-L107 PolarHBondContact O-N 3.42Å
104	L	94.3	Very high	91.7	Very high	29 Å²	29	54.6 Å²	54.6	15%	0.152	27%	0.273	C	S	.	.	H	α-helix	trans	-61.2	-40.9	177	-72.5	171.2	0	0	0	112	D100 K101 L107 A108 L154 A157 K161	D100-L104 WeakPolarHBondContact O-CG 3.45Å; D100-L104 PolarHBondContact O-N 2.92Å; K101-L104 PolarHBondContact O-N 2.9Å; L104-L107 PolarHBondContact O-N 3.18Å; L104-A108 VanDerWaalsContact O-CB 3.28Å; L104-A108 WeakPolarHBondContact O-CB 3.48Å; L104-A108 PolarHBondContact O-N 3.23Å; L104-L154 HydrophobicContact CD2-CD2 3.99Å; L104-A157 HydrophobicContact CD1-CB 4.23Å; L104-A157 HydrophobicContact CD2-CB 4.26Å; L104-K161 HydrophobicContact CD1-CG 3.93Å
105	C	93.2	Very high	92	Very high	3 Å²	3	51.3 Å²	51.3	2%	0.02	26%	0.261	C	S	.	.	H	α-helix	trans	-65.8	-39.7	176.2	-170.8	0	0	0	0	112.2	K101 K102 R103 A108 L109 F158 L251	K101-C105 VanDerWaalsContact O-CB 3.29Å; K101-C105 WeakPolarHBondContact O-CB 3.49Å; K101-C105 PolarHBondContact O-N 3.03Å; K102-C105 PolarHBondContact O-N 3.48Å; R103-C105 VanDerWaalsContact C-N 3.33Å; R103-C105 PolarHBondContact O-N 3.01Å; C105-A108 PolarHBondContact O-N 3.39Å; C105-L109 WeakPolarHBondContact O-CB 3.39Å; C105-L109 PolarHBondContact O-N 3.03Å; C105-F158 HydrophobicContact CB-CD2 4.46Å; C105-F158 HydrophobicContact CB-CE2 4.38Å; C105-L251 HydrophobicContact CB-CD2 3.73Å
106	A	93.7	Very high	92.3	Very high	41 Å²	41	44.1 Å²	44.1	34%	0.339	23%	0.23	S	C	.	.	H	α-helix	trans	-65.4	-43.2	175.5	0	0	0	0	0	111.7	K102 R103 L109 G110	K102-A106 PolarHBondContact O-N 2.68Å; R103-A106 PolarHBondContact O-N 2.86Å; A106-L109 PolarHBondContact O-N 3.4Å; A106-G110 PolarHBondContact O-N 3.22Å
107	L	95.3	Very high	92.5	Very high	103 Å²	103	42.6 Å²	42.6	54%	0.539	23%	0.227	S	C	.	.	H	α-helix	trans	-63.6	-44.5	175.3	-71.1	172	0	0	0	111.4	R103 L104 L109 G110 T111 L154	R103-L107 WeakPolarHBondContact O-CG 3.42Å; R103-L107 PolarHBondContact O-N 3.42Å; L104-L107 PolarHBondContact O-N 3.18Å; L107-L109 PolarHBondContact O-N 3.21Å; L107-G110 PolarHBondContact O-N 3.03Å; L107-T111 WeakPolarHBondContact O-CG2 3.47Å; L107-T111 PolarHBondContact O-N 2.89Å; L107-T111 PolarHBondContact O-OG1 2.92Å; L107-L154 HydrophobicContact CB-CD1 4.16Å; L107-L154 HydrophobicContact CB-CD2 4.36Å
108	A	95.4	Very high	92.6	Very high	4 Å²	4	43.7 Å²	43.7	3%	0.033	23%	0.233	C	C	.	.	H	α-helix	trans	-62.8	-41.2	176.9	0	0	0	0	0	112.1	L104 C105 T111 A112 L151 L154	L104-A108 VanDerWaalsContact O-CB 3.28Å; L104-A108 WeakPolarHBondContact O-CB 3.48Å; L104-A108 PolarHBondContact O-N 3.23Å; C105-A108 PolarHBondContact O-N 3.39Å; A108-T111 WeakPolarHBondContact CA-OG1 3.43Å; A108-T111 PolarHBondContact O-OG1 3.45Å; A108-T111 VanDerWaalsContact O-OG1 3.07Å; A108-A112 VanDerWaalsContact O-CB 3.28Å; A108-A112 WeakPolarHBondContact O-CB 3.37Å; A108-A112 PolarHBondContact O-N 3.01Å; A108-L151 HydrophobicContact CB-CD1 4.03Å; A108-L151 VanDerWaalsContact O-CD1 3.26Å; A108-L151 WeakPolarHBondContact O-CD1 3.38Å; A108-L154 HydrophobicContact CB-CB 4.07Å; A108-L154 HydrophobicContact CB-CD1 4.48Å
109	L	95.1	Very high	92.8	Very high	34 Å²	34	43 Å²	43	18%	0.178	23%	0.229	C	C	.	.	H	α-helix	trans	-63	-45.4	173.1	177	62.6	0	0	0	110.9	C105 A106 L107 T111 A112 L113 L244 V245 A248	C105-L109 WeakPolarHBondContact O-CB 3.39Å; C105-L109 PolarHBondContact O-N 3.03Å; A106-L109 PolarHBondContact O-N 3.4Å; L107-L109 PolarHBondContact O-N 3.21Å; L109-T111 PolarHBondContact O-N 3.41Å; L109-A112 PolarHBondContact O-N 3.37Å; L109-L113 HydrophobicContact CD1-CD1 4.16Å; L109-L113 HydrophobicContact CD1-CG 4.1Å; L109-L113 HydrophobicContact CG-CD1 4.06Å; L109-L113 HydrophobicContact CG-CG 4.4Å; L109-L113 WeakPolarHBondContact O-CB 3.48Å; L109-L113 VanDerWaalsContact O-CG 3.28Å; L109-L113 WeakPolarHBondContact O-CG 3.35Å; L109-L113 PolarHBondContact O-N 3.45Å; L109-L244 HydrophobicContact CD1-CB 4.22Å; L109-V245 HydrophobicContact CD1-CB 4.45Å; L109-V245 HydrophobicContact CD1-CG2 3.63Å; L109-A248 HydrophobicContact CD2-CB 3.67Å
110	G	94.8	Very high	92.8	Very high	34 Å²	34	42.1 Å²	42.1	35%	0.351	23%	0.226	S	C	.	.	H	α-helix	trans	-57.8	-48.5	177.4	0	0	0	0	0	112.5	A106 L107 L113 V114	A106-G110 PolarHBondContact O-N 3.22Å; L107-G110 PolarHBondContact O-N 3.03Å; G110-L113 PolarHBondContact O-N 2.91Å; G110-V114 VanDerWaalsContact O-CG2 3.31Å; G110-V114 WeakPolarHBondContact O-CG2 3.4Å; G110-V114 PolarHBondContact O-N 2.82Å
111	T	95	Very high	92.6	Very high	30 Å²	30	43.7 Å²	43.7	18%	0.184	23%	0.234	C	C	.	.	H	α-helix	trans	-67.2	-36.4	178.6	55.7	0	0	0	0	112.5	L107 A108 L109 V114 G115 L154	L107-T111 WeakPolarHBondContact O-CG2 3.47Å; L107-T111 PolarHBondContact O-N 2.89Å; L107-T111 PolarHBondContact O-OG1 2.92Å; A108-T111 WeakPolarHBondContact CA-OG1 3.43Å; A108-T111 PolarHBondContact O-OG1 3.45Å; A108-T111 VanDerWaalsContact O-OG1 3.07Å; L109-T111 PolarHBondContact O-N 3.41Å; T111-V114 PolarHBondContact O-N 3.36Å; T111-G115 PolarHBondContact O-N 3.15Å; T111-L154 HydrophobicContact CG2-CD1 3.82Å
112	A	94.6	Very high	92.2	Very high	1 Å²	1	43.4 Å²	43.4	1%	0.008	23%	0.233	C	C	.	.	H	α-helix	trans	-63.2	-44.2	173.5	0	0	0	0	0	112.1	A108 L109 G115 I116 L151 R241 L244	A108-A112 VanDerWaalsContact O-CB 3.28Å; A108-A112 WeakPolarHBondContact O-CB 3.37Å; A108-A112 PolarHBondContact O-N 3.01Å; L109-A112 PolarHBondContact O-N 3.37Å; A112-G115 PolarHBondContact O-N 2.87Å; A112-I116 WeakPolarHBondContact O-CG1 3.48Å; A112-I116 PolarHBondContact O-N 3.21Å; A112-L151 HydrophobicContact CB-CD1 4.08Å; A112-L151 HydrophobicContact CB-CD2 4Å; A112-R241 HydrophobicContact CB-CB 4.43Å; A112-L244 HydrophobicContact CB-CD1 3.69Å
113	L	94.3	Very high	91.7	Very high	83 Å²	83	41.7 Å²	41.7	44%	0.435	23%	0.227	S	C	.	.	H	α-helix	trans	-65	-40.1	176.5	-69.6	175.4	0	0	0	111.9	L109 G110 G115 I116 L117 L242	L109-L113 HydrophobicContact CD1-CD1 4.16Å; L109-L113 HydrophobicContact CD1-CG 4.1Å; L109-L113 HydrophobicContact CG-CD1 4.06Å; L109-L113 HydrophobicContact CG-CG 4.4Å; L109-L113 WeakPolarHBondContact O-CB 3.48Å; L109-L113 VanDerWaalsContact O-CG 3.28Å; L109-L113 WeakPolarHBondContact O-CG 3.35Å; L109-L113 PolarHBondContact O-N 3.45Å; G110-L113 PolarHBondContact O-N 2.91Å; L113-G115 VanDerWaalsContact C-N 3.35Å; L113-I116 PolarHBondContact O-N 2.97Å; L113-L117 WeakPolarHBondContact O-CB 3.48Å; L113-L117 PolarHBondContact O-N 3.42Å; L113-L242 HydrophobicContact CD2-CD2 4.16Å
114	V	94.7	Very high	91.2	Very high	77 Å²	77	37.2 Å²	37.2	47%	0.467	21%	0.213	S	C	.	.	H	α-helix	trans	-61.7	-43.6	173.3	169.7	0	0	0	0	110.8	G110 T111 I116 L117 L118	G110-V114 VanDerWaalsContact O-CG2 3.31Å; G110-V114 WeakPolarHBondContact O-CG2 3.4Å; G110-V114 PolarHBondContact O-N 2.82Å; T111-V114 PolarHBondContact O-N 3.36Å; V114-I116 PolarHBondContact O-N 2.94Å; V114-L117 PolarHBondContact O-N 3.03Å; V114-L118 HydrophobicContact CG1-CD1 3.95Å; V114-L118 HydrophobicContact CG1-CG 4.3Å; V114-L118 WeakPolarHBondContact O-CB 3.44Å; V114-L118 VanDerWaalsContact O-CG 3.31Å; V114-L118 WeakPolarHBondContact O-CG 3.5Å; V114-L118 PolarHBondContact O-N 2.86Å
115	G	93	Very high	90.3	Very high	0 Å²	0	38.6 Å²	38.6	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-62.4	-41.9	176.5	0	0	0	0	0	113.1	T111 A112 L113 M119 S147	T111-G115 PolarHBondContact O-N 3.15Å; A112-G115 PolarHBondContact O-N 2.87Å; L113-G115 VanDerWaalsContact C-N 3.35Å; G115-M119 PolarHBondContact O-N 3.04Å; G115-S147 WeakPolarHBondContact CA-OG 3.45Å
116	I	92.3	Very high	89.1	Confident	11 Å²	11	41.3 Å²	41.3	6%	0.056	24%	0.238	C	C	.	.	H	α-helix	trans	-64	-46.1	173.9	-65.3	164.7	0	0	0	110	A112 L113 V114 L118 M119 I120 F239 R241 L242	A112-I116 WeakPolarHBondContact O-CG1 3.48Å; A112-I116 PolarHBondContact O-N 3.21Å; L113-I116 PolarHBondContact O-N 2.97Å; V114-I116 PolarHBondContact O-N 2.94Å; I116-L118 PolarHBondContact O-N 3.25Å; I116-M119 HydrophobicContact CG2-CE 4.48Å; I116-M119 WeakPolarHBondContact O-CB 3.4Å; I116-M119 WeakPolarHBondContact O-CE 3.25Å; I116-M119 PolarHBondContact O-N 3.22Å; I116-M119 VanDerWaalsContact O-N 3.16Å; I116-I120 HydrophobicContact CG2-CD1 4.06Å; I116-I120 HydrophobicContact CG2-CG1 4.39Å; I116-I120 WeakPolarHBondContact O-CG1 3.45Å; I116-I120 PolarHBondContact O-N 3.34Å; I116-F239 HydrophobicContact CG2-CD1 4.5Å; I116-F239 HydrophobicContact CG2-CE1 3.93Å; I116-F239 HydrophobicContact CG2-CE2 4.3Å; I116-F239 HydrophobicContact CG2-CZ 3.82Å; I116-R241 HydrophobicContact CD1-CB 4.48Å; I116-L242 HydrophobicContact CD1-CD2 3.95Å; I116-L242 HydrophobicContact CD1-CG 4.27Å
117	L	92.5	Very high	87.7	Confident	98 Å²	98	43.4 Å²	43.4	51%	0.513	25%	0.249	S	C	.	.	H	α-helix	trans	-60.7	-45.1	178.9	-179.9	64.6	0	0	0	111.9	L113 V114 M119 I120 I121	L113-L117 WeakPolarHBondContact O-CB 3.48Å; L113-L117 PolarHBondContact O-N 3.42Å; V114-L117 PolarHBondContact O-N 3.03Å; L117-M119 VanDerWaalsContact C-N 3.26Å; L117-M119 PolarHBondContact O-N 3.08Å; L117-I120 WeakPolarHBondContact O-CB 3.48Å; L117-I120 PolarHBondContact O-N 2.98Å; L117-I120 VanDerWaalsContact O-N 3.14Å; L117-I121 HydrophobicContact CD1-CD1 4.3Å; L117-I121 HydrophobicContact CG-CD1 3.97Å; L117-I121 WeakPolarHBondContact O-CB 3.37Å; L117-I121 VanDerWaalsContact O-CG1 3.26Å; L117-I121 WeakPolarHBondContact O-CG1 3.37Å; L117-I121 PolarHBondContact O-N 3.38Å
118	L	90.4	Very high	86.3	Confident	42 Å²	42	48 Å²	48	22%	0.22	26%	0.26	C	S	.	.	H	α-helix	trans	-61.2	-36.5	176.2	-73.4	173.6	0	0	0	111.9	V114 I116 I121 H122 I144	V114-L118 HydrophobicContact CG1-CD1 3.95Å; V114-L118 HydrophobicContact CG1-CG 4.3Å; V114-L118 WeakPolarHBondContact O-CB 3.44Å; V114-L118 VanDerWaalsContact O-CG 3.31Å; V114-L118 WeakPolarHBondContact O-CG 3.5Å; V114-L118 PolarHBondContact O-N 2.86Å; I116-L118 PolarHBondContact O-N 3.25Å; L118-I121 PolarHBondContact O-N 2.97Å; L118-H122 WeakPolarHBondContact O-CB 3.45Å; L118-H122 PolarHBondContact O-N 3.26Å; L118-I144 HydrophobicContact CB-CG1 3.75Å
119	M	88.6	Confident	84.5	Confident	1 Å²	1	52.5 Å²	52.5	1%	0.005	29%	0.287	C	S	.	.	H	α-helix	trans	-69.4	-39.4	172.7	173.8	-127.1	59.8	0	0	112.6	G115 I116 L117 I121 H122 A123 I144 P198 M238 F239 W303	G115-M119 PolarHBondContact O-N 3.04Å; I116-M119 HydrophobicContact CG2-CE 4.48Å; I116-M119 WeakPolarHBondContact O-CB 3.4Å; I116-M119 WeakPolarHBondContact O-CE 3.25Å; I116-M119 PolarHBondContact O-N 3.22Å; I116-M119 VanDerWaalsContact O-N 3.16Å; L117-M119 VanDerWaalsContact C-N 3.26Å; L117-M119 PolarHBondContact O-N 3.08Å; M119-I121 VanDerWaalsContact C-N 3.27Å; M119-I121 PolarHBondContact O-N 3.47Å; M119-H122 WeakPolarHBondContact O-CB 3.32Å; M119-H122 PolarHBondContact O-N 3.39Å; M119-A123 WeakPolarHBondContact O-CB 3.28Å; M119-A123 PolarHBondContact O-N 3.4Å; M119-I144 HydrophobicContact CB-CD1 4.3Å; M119-P198 HydrophobicContact CG-CG 4.41Å; M119-M238 HydrophobicContact CB-CE 3.14Å; M119-M238 HydrophobicContact CG-CE 3.04Å; M119-M238 HydrophobicContact SD-CB 4.42Å; M119-M238 HydrophobicContact SD-CE 3.29Å; M119-M238 WeakPolarHBondContact SD-CE 3.44Å; M119-F239 HydrophobicContact CE-CE2 3.78Å; M119-F239 HydrophobicContact CE-CZ 4.14Å; M119-F239 HydrophobicContact SD-CE2 4.25Å; M119-W303 HydrophobicContact CE-CE3 4.45Å; M119-W303 HydrophobicContact CE-CH2 2.99Å; M119-W303 HydrophobicContact CE-CZ2 3.3Å; M119-W303 HydrophobicContact CE-CZ3 3.68Å; M119-W303 HydrophobicContact SD-CH2 3.63Å; M119-W303 HydrophobicContact SD-CZ2 4.38Å; M119-W303 HydrophobicContact SD-CZ3 4.29Å
120	I	88.6	Confident	82.7	Confident	45 Å²	45	52.3 Å²	52.3	23%	0.231	28%	0.284	C	S	.	.	H	α-helix	trans	-58.9	-47.6	174.5	-68.7	174	0	0	0	108.7	I116 L117 H122 A123 E124 F239 W303	I116-I120 HydrophobicContact CG2-CD1 4.06Å; I116-I120 HydrophobicContact CG2-CG1 4.39Å; I116-I120 WeakPolarHBondContact O-CG1 3.45Å; I116-I120 PolarHBondContact O-N 3.34Å; L117-I120 WeakPolarHBondContact O-CB 3.48Å; L117-I120 PolarHBondContact O-N 2.98Å; L117-I120 VanDerWaalsContact O-N 3.14Å; I120-H122 PolarHBondContact O-N 2.82Å; I120-A123 PolarHBondContact O-N 3.03Å; I120-E124 HydrophobicContact CG2-CG 4.37Å; I120-E124 WeakPolarHBondContact O-CG 3.34Å; I120-E124 PolarHBondContact O-N 3.46Å; I120-F239 HydrophobicContact CD1-CZ 4.39Å; I120-F239 HydrophobicContact CG1-CZ 4.49Å; I120-W303 HydrophobicContact CB-CZ2 4.35Å; I120-W303 HydrophobicContact CG1-CD2 4.12Å; I120-W303 HydrophobicContact CG1-CG 4.46Å; I120-W303 HydrophobicContact CG1-CZ2 3.87Å
121	I	86.9	Confident	81	Confident	62 Å²	62	58.4 Å²	58.4	32%	0.318	30%	0.304	S	S	.	.	H	α-helix	trans	-59.8	-46.4	176.7	-68.6	169.2	0	0	0	110.8	L117 L118 M119 A123 E124 I125 I140	L117-I121 HydrophobicContact CD1-CD1 4.3Å; L117-I121 HydrophobicContact CG-CD1 3.97Å; L117-I121 WeakPolarHBondContact O-CB 3.37Å; L117-I121 VanDerWaalsContact O-CG1 3.26Å; L117-I121 WeakPolarHBondContact O-CG1 3.37Å; L117-I121 PolarHBondContact O-N 3.38Å; L118-I121 PolarHBondContact O-N 2.97Å; M119-I121 VanDerWaalsContact C-N 3.27Å; M119-I121 PolarHBondContact O-N 3.47Å; I121-A123 VanDerWaalsContact C-N 3.34Å; I121-A123 PolarHBondContact O-N 3.18Å; I121-E124 PolarHBondContact O-N 3.01Å; I121-I125 HydrophobicContact CG2-CD1 3.42Å; I121-I125 VanDerWaalsContact CG2-CD1 3.42Å; I121-I125 HydrophobicContact CG2-CG1 4.22Å; I121-I125 WeakPolarHBondContact O-CB 3.25Å; I121-I125 WeakPolarHBondContact O-CG1 3.38Å; I121-I125 PolarHBondContact O-N 3.17Å; I121-I140 HydrophobicContact CG2-CD1 4.3Å
122	H	81.8	Confident	79	Confident	9 Å²	9	63.1 Å²	63.1	4%	0.042	34%	0.335	C	S	.	.	H	α-helix	trans	-56	-49.5	175.7	-177	-104.4	0	0	0	111.2	L118 M119 I120 E124 I125 C126 I140 N141 I144 E231	L118-H122 WeakPolarHBondContact O-CB 3.45Å; L118-H122 PolarHBondContact O-N 3.26Å; M119-H122 WeakPolarHBondContact O-CB 3.32Å; M119-H122 PolarHBondContact O-N 3.39Å; I120-H122 PolarHBondContact O-N 2.82Å; H122-E124 PolarHBondContact O-N 3.43Å; H122-I125 PolarHBondContact O-N 3.45Å; H122-C126 VanDerWaalsContact O-CB 3.25Å; H122-C126 WeakPolarHBondContact O-CB 3.47Å; H122-C126 PolarHBondContact O-N 3.45Å; H122-I140 HydrophobicContact CB-CG2 3.74Å; H122-N141 PolarHBondContact CD2-OD1 2.98Å; H122-N141 PolarHBondContact NE2-ND2 3.49Å; H122-N141 PolarHBondContact NE2-OD1 3.49Å; H122-I144 HydrophobicContact CB-CD1 4.07Å; H122-E231 IonicContact CE1-OE1 2.75Å
123	A	78.9	Confident	77.3	Confident	11 Å²	11	66.7 Å²	66.7	9%	0.091	37%	0.372	C	S	.	.	H	α-helix	trans	-66.2	-36.2	-177.5	0	0	0	0	0	112.8	M119 I120 I121 P127 W303 L307 R310	M119-A123 WeakPolarHBondContact O-CB 3.28Å; M119-A123 PolarHBondContact O-N 3.4Å; I120-A123 PolarHBondContact O-N 3.03Å; I121-A123 VanDerWaalsContact C-N 3.34Å; I121-A123 PolarHBondContact O-N 3.18Å; A123-P127 WeakPolarHBondContact O-CD 3.49Å; A123-W303 HydrophobicContact CB-CZ2 3.94Å; A123-L307 HydrophobicContact CB-CD1 4.49Å; A123-R310 PolarHBondContact O-NH1 3.34Å
124	E	81.4	Confident	76	Confident	63 Å²	63	64.6 Å²	64.6	29%	0.294	36%	0.364	S	S	.	.	H	α-helix	trans	-77.2	-34.8	177.8	-67.9	-53.9	137.5	0	0	112.7	I120 I121 H122 P127 Y128 R310	I120-E124 HydrophobicContact CG2-CG 4.37Å; I120-E124 WeakPolarHBondContact O-CG 3.34Å; I120-E124 PolarHBondContact O-N 3.46Å; I121-E124 PolarHBondContact O-N 3.01Å; H122-E124 PolarHBondContact O-N 3.43Å; E124-P127 WeakPolarHBondContact O-CD 3.29Å; E124-Y128 WeakPolarHBondContact O-CD2 3.43Å; E124-R310 VanDerWaalsContact CD-NH2 3.28Å; E124-R310 IonicContact OE1-CZ 2.56Å; E124-R310 IonicContact OE1-NH2 3.98Å; E124-R310 PolarHBondContact OE1-NH2 2.8Å; E124-R310 IonicContact OE2-NH2 3.94Å; E124-R310 PolarHBondContact OE2-NH2 2.59Å
125	I	76.6	Confident	75.1	Confident	58 Å²	58	69.7 Å²	69.7	30%	0.297	38%	0.38	S	S	.	.	H	α-helix	trans	-83.5	-30.3	-176.7	-60.4	178.5	0	0	0	111.7	I121 H122 Y128 V129 Y130	I121-I125 HydrophobicContact CG2-CD1 3.42Å; I121-I125 VanDerWaalsContact CG2-CD1 3.42Å; I121-I125 HydrophobicContact CG2-CG1 4.22Å; I121-I125 WeakPolarHBondContact O-CB 3.25Å; I121-I125 WeakPolarHBondContact O-CG1 3.38Å; I121-I125 PolarHBondContact O-N 3.17Å; H122-I125 PolarHBondContact O-N 3.45Å; I125-Y128 PolarHBondContact O-N 3.33Å; I125-Y128 VanDerWaalsContact O-N 3.09Å; I125-V129 HydrophobicContact CG2-CB 3.72Å; I125-V129 HydrophobicContact CG2-CG1 4.39Å; I125-V129 HydrophobicContact CG2-CG2 3.79Å; I125-V129 PolarHBondContact O-N 3.33Å; I125-Y130 HydrophobicContact CB-CD2 4.45Å; I125-Y130 HydrophobicContact CB-CE2 3.83Å; I125-Y130 HydrophobicContact CG2-CD2 3.86Å; I125-Y130 HydrophobicContact CG2-CE2 3.3Å; I125-Y130 WeakPolarHBondContact O-CD2 3.23Å
126	C	67.8	Low	74.3	Confident	60 Å²	60	73.5 Å²	73.5	41%	0.405	40%	0.403	S	S	.	.	H	α-helix	trans	-39.9	-54.5	177.7	-168.5	0	0	0	0	114.2	H122 Y128 Y130	H122-C126 VanDerWaalsContact O-CB 3.25Å; H122-C126 WeakPolarHBondContact O-CB 3.47Å; H122-C126 PolarHBondContact O-N 3.45Å; C126-Y128 PolarHBondContact O-N 2.88Å; C126-Y130 VanDerWaalsContact CA-CD2 3.48Å
127	P	64.8	Low	73.5	Confident	86 Å²	86	74 Å²	74	56%	0.558	41%	0.407	S	S	*	.	H	α-helix	trans	-73.3	-19.7	-175.8	27.4	-35.7	0	0	0	115.7	A123 E124	A123-P127 WeakPolarHBondContact O-CD 3.49Å; E124-P127 WeakPolarHBondContact O-CD 3.29Å
128	Y	64.8	Low	72.7	Confident	199 Å²	199	73 Å²	73	78%	0.78	40%	0.402	S	S	*	.	H	α-helix	trans	-103.2	-30.6	-171	-67.8	-75.1	0	0	0	114.4	E124 I125 C126	E124-Y128 WeakPolarHBondContact O-CD2 3.43Å; I125-Y128 PolarHBondContact O-N 3.33Å; I125-Y128 VanDerWaalsContact O-N 3.09Å; C126-Y128 PolarHBondContact O-N 2.88Å
129	V	57.5	Low	72.4	Confident	98 Å²	98	74.9 Å²	74.9	59%	0.594	42%	0.415	S	S	*	.	H	α-helix	trans	-123.9	-16.7	-164.3	-177.3	0	0	0	0	112.8	I125	I125-V129 HydrophobicContact CG2-CB 3.72Å; I125-V129 HydrophobicContact CG2-CG1 4.39Å; I125-V129 HydrophobicContact CG2-CG2 3.79Å; I125-V129 PolarHBondContact O-N 3.33Å
130	Y	57.9	Low	72.1	Confident	31 Å²	31	75.9 Å²	75.9	12%	0.122	42%	0.42	C	S	.	.			trans	-102	109.6	-169.9	-70.3	-73	0	0	0	113	I125 C126 S134 V136 S137 I140	I125-Y130 HydrophobicContact CB-CD2 4.45Å; I125-Y130 HydrophobicContact CB-CE2 3.83Å; I125-Y130 HydrophobicContact CG2-CD2 3.86Å; I125-Y130 HydrophobicContact CG2-CE2 3.3Å; I125-Y130 WeakPolarHBondContact O-CD2 3.23Å; C126-Y130 VanDerWaalsContact CA-CD2 3.48Å; Y130-S134 VanDerWaalsContact CD1-OG 3.24Å; Y130-S134 WeakPolarHBondContact CD1-OG 3.47Å; Y130-S134 WeakPolarHBondContact CE1-OG 3.29Å; Y130-V136 VanDerWaalsContact CE1-C 3.45Å; Y130-V136 HydrophobicContact CE1-CB 3.63Å; Y130-V136 HydrophobicContact CE1-CG1 3.79Å; Y130-V136 WeakPolarHBondContact OH-CG1 3.33Å; Y130-V136 PolarHBondContact OH-O 3.47Å; Y130-S137 VanDerWaalsContact CD1-CB 3.49Å; Y130-S137 VanDerWaalsContact CE1-CB 3.44Å; Y130-I140 WeakPolarHBondContact OH-CD1 3.34Å
131	E	58.1	Low	71.8	Confident	162 Å²	162	73.9 Å²	73.9	76%	0.757	41%	0.41	S	S	*	.			trans	-69.2	137.3	147.6	-69.5	-173.5	165.9	0	0	108.7	G133 S134	E131-G133 PolarHBondContact O-N 3.47Å; E131-G133 VanDerWaalsContact O-N 3.08Å; E131-S134 PolarHBondContact O-N 2.92Å
132	P	54.6	Low	71.8	Confident	128 Å²	128	73.4 Å²	73.4	83%	0.831	41%	0.412	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.6	117.2	177.4	20.4	-29.4	0	0	0	109.8
133	G	57.7	Low	72.2	Confident	77 Å²	77	75.1 Å²	75.1	79%	0.794	43%	0.425	S	S	*	.	T	Hydrogen-bonded Turn	trans	108.1	4	-178.2	0	0	0	0	0	116.7	E131	E131-G133 PolarHBondContact O-N 3.47Å; E131-G133 VanDerWaalsContact O-N 3.08Å
134	S	67.7	Low	72.7	Confident	38 Å²	38	74.6 Å²	74.6	27%	0.266	42%	0.42	S	S	.	.			trans	-68.5	143.5	178.4	109.2	0	0	0	0	113.1	Y130 E131 V136 S137	Y130-S134 VanDerWaalsContact CD1-OG 3.24Å; Y130-S134 WeakPolarHBondContact CD1-OG 3.47Å; Y130-S134 WeakPolarHBondContact CE1-OG 3.29Å; E131-S134 PolarHBondContact O-N 2.92Å; S134-V136 PolarHBondContact O-N 3.3Å; S134-V136 PolarHBondContact OG-N 2.93Å; S134-S137 PolarHBondContact O-N 3.41Å
135	K	75.6	Confident	73.1	Confident	184 Å²	184	73 Å²	73	80%	0.8	42%	0.416	S	S	*	.	H	α-helix	trans	-53.7	-28.6	177.9	-65.6	-177.5	-179.1	177.9	0	112.8	V139	K135-V139 VanDerWaalsContact O-CG2 3.24Å; K135-V139 WeakPolarHBondContact O-CG2 3.35Å; K135-V139 PolarHBondContact O-N 2.9Å; K135-V139 VanDerWaalsContact O-N 3.14Å
136	V	76.4	Confident	73.9	Confident	81 Å²	81	76.4 Å²	76.4	49%	0.491	44%	0.435	S	S	.	.	H	α-helix	trans	-73.5	-31.7	-176.6	-177.2	0	0	0	0	110.8	Y130 S134 V139 I140	Y130-V136 VanDerWaalsContact CE1-C 3.45Å; Y130-V136 HydrophobicContact CE1-CB 3.63Å; Y130-V136 HydrophobicContact CE1-CG1 3.79Å; Y130-V136 WeakPolarHBondContact OH-CG1 3.33Å; Y130-V136 PolarHBondContact OH-O 3.47Å; S134-V136 PolarHBondContact O-N 3.3Å; S134-V136 PolarHBondContact OG-N 2.93Å; V136-V139 PolarHBondContact O-N 3.48Å; V136-I140 WeakPolarHBondContact O-CG1 3.45Å; V136-I140 PolarHBondContact O-N 2.8Å; V136-I140 VanDerWaalsContact O-N 3.17Å
137	S	74	Confident	75.2	Confident	21 Å²	21	74.3 Å²	74.3	15%	0.147	42%	0.42	C	S	.	.	H	α-helix	trans	-75.2	-41.9	-178	170.7	0	0	0	0	108.8	Y130 S134 V139 I140 N141	Y130-S137 VanDerWaalsContact CD1-CB 3.49Å; Y130-S137 VanDerWaalsContact CE1-CB 3.44Å; S134-S137 PolarHBondContact O-N 3.41Å; S137-V139 VanDerWaalsContact C-N 3.33Å; S137-V139 PolarHBondContact O-N 3.36Å; S137-I140 PolarHBondContact O-N 2.97Å; S137-N141 WeakPolarHBondContact O-CB 3.35Å; S137-N141 PolarHBondContact O-N 3.28Å; S137-N141 PolarHBondContact O-ND2 2.99Å
138	L	76.1	Confident	76.6	Confident	76 Å²	76	70.5 Å²	70.5	40%	0.398	40%	0.395	S	S	.	.	H	α-helix	trans	-57.1	-44.4	172.6	-171.8	150.5	0	0	0	111.8	N141 C142	L138-N141 PolarHBondContact O-N 3.26Å; L138-C142 VanDerWaalsContact O-CB 3.27Å; L138-C142 WeakPolarHBondContact O-CB 3.42Å; L138-C142 PolarHBondContact O-N 3.31Å; L138-C142 PolarHBondContact O-SG 2.91Å; L138-C142 VanDerWaalsContact O-SG 3.33Å
139	V	84.1	Confident	78	Confident	83 Å²	83	62.4 Å²	62.4	50%	0.503	37%	0.373	S	S	.	.	H	α-helix	trans	-64	-42.9	178.4	169	0	0	0	0	112.2	K135 V136 S137 C142 S143	K135-V139 VanDerWaalsContact O-CG2 3.24Å; K135-V139 WeakPolarHBondContact O-CG2 3.35Å; K135-V139 PolarHBondContact O-N 2.9Å; K135-V139 VanDerWaalsContact O-N 3.14Å; V136-V139 PolarHBondContact O-N 3.48Å; S137-V139 VanDerWaalsContact C-N 3.33Å; S137-V139 PolarHBondContact O-N 3.36Å; V139-C142 PolarHBondContact O-N 3.44Å; V139-S143 WeakPolarHBondContact O-CB 3.41Å; V139-S143 PolarHBondContact O-N 3.38Å; V139-S143 PolarHBondContact O-OG 2.99Å
140	I	83.1	Confident	79.8	Confident	21 Å²	21	60.3 Å²	60.3	11%	0.108	36%	0.362	C	S	.	.	H	α-helix	trans	-66.8	-45.7	177.9	-65.2	-173	0	0	0	110.6	I121 H122 Y130 V136 S137 C142 S143 I144	I121-I140 HydrophobicContact CG2-CD1 4.3Å; H122-I140 HydrophobicContact CB-CG2 3.74Å; Y130-I140 WeakPolarHBondContact OH-CD1 3.34Å; V136-I140 WeakPolarHBondContact O-CG1 3.45Å; V136-I140 PolarHBondContact O-N 2.8Å; V136-I140 VanDerWaalsContact O-N 3.17Å; S137-I140 PolarHBondContact O-N 2.97Å; I140-C142 VanDerWaalsContact C-N 3.28Å; I140-C142 PolarHBondContact O-N 3.48Å; I140-S143 WeakPolarHBondContact O-CB 3.3Å; I140-S143 PolarHBondContact O-N 2.9Å; I140-S143 VanDerWaalsContact O-N 3.07Å; I140-I144 HydrophobicContact CG2-CD1 3.96Å; I140-I144 HydrophobicContact CG2-CG1 4.4Å; I140-I144 WeakPolarHBondContact O-CG1 3.45Å; I140-I144 PolarHBondContact O-N 2.95Å
141	N	82.6	Confident	81.6	Confident	3 Å²	3	58.9 Å²	58.9	2%	0.016	36%	0.356	C	S	.	.	H	α-helix	trans	-64.8	-32.8	177.6	-70.7	-28	0	0	0	112.4	H122 S137 L138 S143 I144 S145 S201 Y202	H122-N141 PolarHBondContact CD2-OD1 2.98Å; H122-N141 PolarHBondContact NE2-ND2 3.49Å; H122-N141 PolarHBondContact NE2-OD1 3.49Å; S137-N141 WeakPolarHBondContact O-CB 3.35Å; S137-N141 PolarHBondContact O-N 3.28Å; S137-N141 PolarHBondContact O-ND2 2.99Å; L138-N141 PolarHBondContact O-N 3.26Å; N141-S143 VanDerWaalsContact C-N 3.33Å; N141-I144 PolarHBondContact O-N 3.46Å; N141-S145 WeakPolarHBondContact O-CB 3.31Å; N141-S145 PolarHBondContact O-N 2.82Å; N141-S145 PolarHBondContact O-OG 2.98Å; N141-S201 PolarHBondContact ND2-OG 2.99Å; N141-Y202 HydrophobicContact CB-CE2 3.97Å; N141-Y202 PolarHBondContact O-OH 3.43Å
142	C	86.6	Confident	83.4	Confident	52 Å²	52	52.7 Å²	52.7	35%	0.351	33%	0.328	S	S	.	.	H	α-helix	trans	-65.9	-41.6	173.1	-84.4	0	0	0	0	110.1	L138 V139 I140 S145 L146 Y202	L138-C142 VanDerWaalsContact O-CB 3.27Å; L138-C142 WeakPolarHBondContact O-CB 3.42Å; L138-C142 PolarHBondContact O-N 3.31Å; L138-C142 PolarHBondContact O-SG 2.91Å; L138-C142 VanDerWaalsContact O-SG 3.33Å; V139-C142 PolarHBondContact O-N 3.44Å; I140-C142 VanDerWaalsContact C-N 3.28Å; I140-C142 PolarHBondContact O-N 3.48Å; C142-S145 PolarHBondContact O-N 2.89Å; C142-L146 WeakPolarHBondContact O-CB 3.36Å; C142-L146 PolarHBondContact O-N 3.42Å; C142-Y202 WeakPolarHBondContact CA-OH 3.41Å; C142-Y202 WeakPolarHBondContact CB-OH 3.32Å; C142-Y202 PolarHBondContact N-OH 2.93Å; C142-Y202 PolarHBondContact SG-OH 3.39Å
143	S	89.8	Confident	85.4	Confident	45 Å²	45	52.2 Å²	52.2	32%	0.315	32%	0.317	S	S	.	.	H	α-helix	trans	-68.1	-39.9	179.4	-59	0	0	0	0	111.8	V139 I140 N141 S147	V139-S143 WeakPolarHBondContact O-CB 3.41Å; V139-S143 PolarHBondContact O-N 3.38Å; V139-S143 PolarHBondContact O-OG 2.99Å; I140-S143 WeakPolarHBondContact O-CB 3.3Å; I140-S143 PolarHBondContact O-N 2.9Å; I140-S143 VanDerWaalsContact O-N 3.07Å; N141-S143 VanDerWaalsContact C-N 3.33Å; S143-S147 WeakPolarHBondContact O-CB 3.43Å; S143-S147 PolarHBondContact O-N 2.89Å; S143-S147 PolarHBondContact O-OG 3.31Å
144	I	89.8	Confident	87.3	Confident	0 Å²	0	49.7 Å²	49.7	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-60.8	-53.9	172.5	-65.6	167.3	0	0	0	108.9	L118 M119 H122 I140 N141 L146 S147 T148 H197	L118-I144 HydrophobicContact CB-CG1 3.75Å; M119-I144 HydrophobicContact CB-CD1 4.3Å; H122-I144 HydrophobicContact CB-CD1 4.07Å; I140-I144 HydrophobicContact CG2-CD1 3.96Å; I140-I144 HydrophobicContact CG2-CG1 4.4Å; I140-I144 WeakPolarHBondContact O-CG1 3.45Å; I140-I144 PolarHBondContact O-N 2.95Å; N141-I144 PolarHBondContact O-N 3.46Å; I144-L146 VanDerWaalsContact C-N 3.35Å; I144-L146 PolarHBondContact O-N 2.97Å; I144-S147 WeakPolarHBondContact O-CB 3.38Å; I144-S147 PolarHBondContact O-N 3.34Å; I144-S147 VanDerWaalsContact O-N 3.08Å; I144-S147 PolarHBondContact O-OG 3.4Å; I144-T148 HydrophobicContact CG2-CG2 4.43Å; I144-T148 WeakPolarHBondContact O-CG2 3.45Å; I144-T148 PolarHBondContact O-N 2.92Å; I144-H197 HydrophobicContact CG2-CB 4.27Å
145	S	90.8	Very high	88.6	Confident	30 Å²	30	48 Å²	48	21%	0.21	27%	0.273	C	S	.	.	H	α-helix	trans	-58.7	-44.1	-179.3	-54.5	0	0	0	0	112.1	N141 C142 S147 T148 G149 H197	N141-S145 WeakPolarHBondContact O-CB 3.31Å; N141-S145 PolarHBondContact O-N 2.82Å; N141-S145 PolarHBondContact O-OG 2.98Å; C142-S145 PolarHBondContact O-N 2.89Å; S145-S147 PolarHBondContact O-N 3.34Å; S145-T148 PolarHBondContact O-N 3.12Å; S145-T148 PolarHBondContact O-OG1 2.94Å; S145-G149 PolarHBondContact O-N 3.41Å; S145-H197 PolarHBondContact OG-NE2 3.47Å
146	L	93.1	Very high	89.5	Confident	130 Å²	130	43.7 Å²	43.7	68%	0.681	26%	0.258	S	S	*	.	H	α-helix	trans	-61.4	-42.6	175.2	-179.9	63.2	0	0	0	111.9	C142 I144 T148 G149 C150	C142-L146 WeakPolarHBondContact O-CB 3.36Å; C142-L146 PolarHBondContact O-N 3.42Å; I144-L146 VanDerWaalsContact C-N 3.35Å; I144-L146 PolarHBondContact O-N 2.97Å; L146-T148 VanDerWaalsContact C-N 3.29Å; L146-T148 PolarHBondContact O-N 3.49Å; L146-G149 PolarHBondContact O-N 3.39Å; L146-C150 WeakPolarHBondContact O-CB 3.39Å; L146-C150 PolarHBondContact O-N 3.43Å
147	S	94.6	Very high	90.4	Very high	15 Å²	15	41.4 Å²	41.4	11%	0.105	25%	0.248	C	C	.	.	H	α-helix	trans	-62.8	-36.7	176	78.6	0	0	0	0	111.8	G115 S143 I144 S145 L151	G115-S147 WeakPolarHBondContact CA-OG 3.45Å; S143-S147 WeakPolarHBondContact O-CB 3.43Å; S143-S147 PolarHBondContact O-N 2.89Å; S143-S147 PolarHBondContact O-OG 3.31Å; I144-S147 WeakPolarHBondContact O-CB 3.38Å; I144-S147 PolarHBondContact O-N 3.34Å; I144-S147 VanDerWaalsContact O-N 3.08Å; I144-S147 PolarHBondContact O-OG 3.4Å; S145-S147 PolarHBondContact O-N 3.34Å; S147-L151 WeakPolarHBondContact O-CB 3.41Å; S147-L151 PolarHBondContact O-N 3.48Å
148	T	94.1	Very high	91.4	Very high	6 Å²	6	41.3 Å²	41.3	4%	0.037	25%	0.245	C	C	.	.	H	α-helix	trans	-69.2	-42.6	175.5	75.5	0	0	0	0	112	I144 S145 L146 C150 L151 L152 H197 R241	I144-T148 HydrophobicContact CG2-CG2 4.43Å; I144-T148 WeakPolarHBondContact O-CG2 3.45Å; I144-T148 PolarHBondContact O-N 2.92Å; S145-T148 PolarHBondContact O-N 3.12Å; S145-T148 PolarHBondContact O-OG1 2.94Å; L146-T148 VanDerWaalsContact C-N 3.29Å; L146-T148 PolarHBondContact O-N 3.49Å; T148-C150 VanDerWaalsContact C-N 3.33Å; T148-C150 PolarHBondContact O-N 2.96Å; T148-L151 WeakPolarHBondContact O-CB 3.35Å; T148-L151 PolarHBondContact O-N 3.37Å; T148-L151 VanDerWaalsContact O-N 3.17Å; T148-L152 VanDerWaalsContact O-CG 3.31Å; T148-L152 WeakPolarHBondContact O-CG 3.35Å; T148-L152 PolarHBondContact O-N 2.87Å; T148-H197 HydrophobicContact CG2-CB 3.75Å; T148-H197 PolarHBondContact OG1-CE1 2.93Å; T148-R241 VanDerWaalsContact CG2-NH2 3.29Å
149	G	94.6	Very high	92.2	Very high	29 Å²	29	38.6 Å²	38.6	30%	0.299	23%	0.23	S	C	.	.	H	α-helix	trans	-60.3	-44.5	175.3	0	0	0	0	0	111.6	S145 L146 L151 L152 I153	S145-G149 PolarHBondContact O-N 3.41Å; L146-G149 PolarHBondContact O-N 3.39Å; G149-L151 PolarHBondContact O-N 3.39Å; G149-L152 PolarHBondContact O-N 2.89Å; G149-I153 WeakPolarHBondContact O-CG1 3.47Å; G149-I153 PolarHBondContact O-N 2.94Å; G149-I153 VanDerWaalsContact O-N 3.08Å
150	C	95.6	Very high	92.6	Very high	55 Å²	55	40.4 Å²	40.4	37%	0.372	23%	0.229	S	C	.	.	H	α-helix	trans	-60.2	-44.8	173.6	-174.2	0	0	0	0	111.8	L146 T148 L152 I153 L154	L146-C150 WeakPolarHBondContact O-CB 3.39Å; L146-C150 PolarHBondContact O-N 3.43Å; T148-C150 VanDerWaalsContact C-N 3.33Å; T148-C150 PolarHBondContact O-N 2.96Å; C150-L152 PolarHBondContact O-N 3.27Å; C150-I153 PolarHBondContact O-N 2.92Å; C150-L154 VanDerWaalsContact O-CG 3.3Å; C150-L154 WeakPolarHBondContact O-CG 3.13Å; C150-L154 PolarHBondContact O-N 3.35Å
151	L	95.7	Very high	93	Very high	0 Å²	0	41.8 Å²	41.8	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-58.7	-45.5	176.2	177.8	62.5	0	0	0	112.3	A108 A112 S147 T148 G149 I153 L154 I155 C194 L244	A108-L151 HydrophobicContact CB-CD1 4.03Å; A108-L151 VanDerWaalsContact O-CD1 3.26Å; A108-L151 WeakPolarHBondContact O-CD1 3.38Å; A112-L151 HydrophobicContact CB-CD1 4.08Å; A112-L151 HydrophobicContact CB-CD2 4Å; S147-L151 WeakPolarHBondContact O-CB 3.41Å; S147-L151 PolarHBondContact O-N 3.48Å; T148-L151 WeakPolarHBondContact O-CB 3.35Å; T148-L151 PolarHBondContact O-N 3.37Å; T148-L151 VanDerWaalsContact O-N 3.17Å; G149-L151 PolarHBondContact O-N 3.39Å; L151-I153 PolarHBondContact O-N 2.93Å; L151-L154 PolarHBondContact O-N 3.35Å; L151-I155 HydrophobicContact CD1-CD1 4.08Å; L151-I155 HydrophobicContact CD1-CG1 4.33Å; L151-I155 HydrophobicContact CG-CD1 3.94Å; L151-I155 WeakPolarHBondContact O-CG1 3.39Å; L151-I155 PolarHBondContact O-N 3.5Å; L151-C194 HydrophobicContact CD2-CB 4.16Å; L151-L244 HydrophobicContact CD1-CD1 3.89Å
152	L	95.9	Very high	93.4	Very high	33 Å²	33	43.5 Å²	43.5	17%	0.173	24%	0.243	C	C	.	.	H	α-helix	trans	-62.7	-43.2	178.9	-66.9	169.3	0	0	0	111.7	T148 G149 C150 L154 I155 I156 L191 C194 V195	T148-L152 VanDerWaalsContact O-CG 3.31Å; T148-L152 WeakPolarHBondContact O-CG 3.35Å; T148-L152 PolarHBondContact O-N 2.87Å; G149-L152 PolarHBondContact O-N 2.89Å; C150-L152 PolarHBondContact O-N 3.27Å; L152-L154 VanDerWaalsContact C-N 3.31Å; L152-L154 PolarHBondContact O-N 2.86Å; L152-I155 PolarHBondContact O-N 3.32Å; L152-I156 VanDerWaalsContact O-CG1 3.31Å; L152-I156 WeakPolarHBondContact O-CG1 3.5Å; L152-I156 PolarHBondContact O-N 2.96Å; L152-L191 HydrophobicContact CD2-CB 4.41Å; L152-L191 HydrophobicContact CD2-CD2 3.71Å; L152-C194 HydrophobicContact CD2-CB 3.72Å; L152-V195 HydrophobicContact CD1-CG2 3.58Å; L152-V195 HydrophobicContact CD2-CG2 3.77Å; L152-V195 HydrophobicContact CG-CG2 4.33Å
153	I	96.6	Very high	93.5	Very high	117 Å²	117	42.6 Å²	42.6	60%	0.6	24%	0.235	S	C	*	.	H	α-helix	trans	-59.4	-43.8	175	-67.1	165.1	0	0	0	110.5	G149 C150 L151 I156 A157	G149-I153 WeakPolarHBondContact O-CG1 3.47Å; G149-I153 PolarHBondContact O-N 2.94Å; G149-I153 VanDerWaalsContact O-N 3.08Å; C150-I153 PolarHBondContact O-N 2.92Å; L151-I153 PolarHBondContact O-N 2.93Å; I153-I156 PolarHBondContact O-N 3.36Å; I153-A157 WeakPolarHBondContact O-CB 3.4Å; I153-A157 PolarHBondContact O-N 2.99Å
154	L	95.9	Very high	93.5	Very high	24 Å²	24	46.3 Å²	46.3	13%	0.126	24%	0.242	C	C	.	.	H	α-helix	trans	-65.7	-37.8	178.6	-68.7	170	0	0	0	112.5	L104 L107 A108 T111 C150 L151 L152 A157 F158	L104-L154 HydrophobicContact CD2-CD2 3.99Å; L107-L154 HydrophobicContact CB-CD1 4.16Å; L107-L154 HydrophobicContact CB-CD2 4.36Å; A108-L154 HydrophobicContact CB-CB 4.07Å; A108-L154 HydrophobicContact CB-CD1 4.48Å; T111-L154 HydrophobicContact CG2-CD1 3.82Å; C150-L154 VanDerWaalsContact O-CG 3.3Å; C150-L154 WeakPolarHBondContact O-CG 3.13Å; C150-L154 PolarHBondContact O-N 3.35Å; L151-L154 PolarHBondContact O-N 3.35Å; L152-L154 VanDerWaalsContact C-N 3.31Å; L152-L154 PolarHBondContact O-N 2.86Å; L154-A157 PolarHBondContact O-N 2.87Å; L154-F158 WeakPolarHBondContact O-CB 3.35Å; L154-F158 PolarHBondContact O-N 2.91Å
155	I	95.4	Very high	93.4	Very high	2 Å²	2	47.4 Å²	47.4	1%	0.01	25%	0.247	C	C	.	.	H	α-helix	trans	-66.1	-43.4	175.5	-69.5	168	0	0	0	110.8	L151 L152 F158 H159 E190 L191 C194	L151-I155 HydrophobicContact CD1-CD1 4.08Å; L151-I155 HydrophobicContact CD1-CG1 4.33Å; L151-I155 HydrophobicContact CG-CD1 3.94Å; L151-I155 WeakPolarHBondContact O-CG1 3.39Å; L151-I155 PolarHBondContact O-N 3.5Å; L152-I155 PolarHBondContact O-N 3.32Å; I155-F158 WeakPolarHBondContact O-CB 3.45Å; I155-F158 PolarHBondContact O-N 3.47Å; I155-H159 PolarHBondContact O-CD2 3.3Å; I155-H159 VanDerWaalsContact O-CD2 3.31Å; I155-H159 PolarHBondContact O-N 2.98Å; I155-E190 HydrophobicContact CG2-CG 4.27Å; I155-L191 HydrophobicContact CB-CD2 4.28Å; I155-L191 HydrophobicContact CG2-CD2 3.88Å; I155-C194 HydrophobicContact CD1-CB 3.78Å; I155-C194 WeakPolarHBondContact CD1-SG 3.36Å
156	I	95.5	Very high	93.2	Very high	95 Å²	95	48.8 Å²	48.8	49%	0.487	25%	0.25	S	C	.	.	H	α-helix	trans	-62.1	-45.7	175.3	-66.7	167.5	0	0	0	110.1	L152 I153 F158 H159 Y160 L191	L152-I156 VanDerWaalsContact O-CG1 3.31Å; L152-I156 WeakPolarHBondContact O-CG1 3.5Å; L152-I156 PolarHBondContact O-N 2.96Å; I153-I156 PolarHBondContact O-N 3.36Å; I156-F158 VanDerWaalsContact C-N 3.3Å; I156-F158 PolarHBondContact O-N 3.22Å; I156-H159 PolarHBondContact O-N 2.96Å; I156-Y160 WeakPolarHBondContact O-CB 3.33Å; I156-Y160 PolarHBondContact O-N 3.41Å; I156-L191 HydrophobicContact CD1-CD2 4.44Å; I156-L191 HydrophobicContact CG1-CD1 4.37Å; I156-L191 HydrophobicContact CG1-CD2 3.98Å
157	A	95.2	Very high	93	Very high	33 Å²	33	44.4 Å²	44.4	27%	0.273	23%	0.226	S	C	.	.	H	α-helix	trans	-60.9	-38.8	176.7	0	0	0	0	0	112.3	L104 I153 L154 K161	L104-A157 HydrophobicContact CD1-CB 4.23Å; L104-A157 HydrophobicContact CD2-CB 4.26Å; I153-A157 WeakPolarHBondContact O-CB 3.4Å; I153-A157 PolarHBondContact O-N 2.99Å; L154-A157 PolarHBondContact O-N 2.87Å; A157-K161 WeakPolarHBondContact O-CG 3.35Å; A157-K161 PolarHBondContact O-N 3.02Å; A157-K161 VanDerWaalsContact O-N 3.08Å
158	F	94.6	Very high	92.6	Very high	19 Å²	19	45.6 Å²	45.6	8%	0.083	23%	0.231	C	C	.	.	H	α-helix	trans	-61.7	-48.9	175.1	173.7	-91.8	0	0	0	112	K101 C105 L154 I155 I156 K161 D162 L251	K101-F158 HydrophobicContact CB-CD2 4.44Å; K101-F158 HydrophobicContact CB-CE2 4.25Å; C105-F158 HydrophobicContact CB-CD2 4.46Å; C105-F158 HydrophobicContact CB-CE2 4.38Å; L154-F158 WeakPolarHBondContact O-CB 3.35Å; L154-F158 PolarHBondContact O-N 2.91Å; I155-F158 WeakPolarHBondContact O-CB 3.45Å; I155-F158 PolarHBondContact O-N 3.47Å; I156-F158 VanDerWaalsContact C-N 3.3Å; I156-F158 PolarHBondContact O-N 3.22Å; F158-K161 PolarHBondContact O-N 3.21Å; F158-D162 PolarHBondContact O-N 3.24Å; F158-L251 HydrophobicContact CE2-CD2 3.91Å
159	H	93.3	Very high	92.1	Very high	19 Å²	19	48.7 Å²	48.7	9%	0.088	25%	0.248	C	C	.	.	H	α-helix	trans	-68.7	-35	179.2	-78.5	-62.8	0	0	0	112.7	I155 I156 K161 D162 I163 I187 E190	I155-H159 PolarHBondContact O-CD2 3.3Å; I155-H159 VanDerWaalsContact O-CD2 3.31Å; I155-H159 PolarHBondContact O-N 2.98Å; I156-H159 PolarHBondContact O-N 2.96Å; H159-K161 VanDerWaalsContact C-N 3.33Å; H159-K161 PolarHBondContact O-N 3.18Å; H159-D162 WeakPolarHBondContact O-CB 3.3Å; H159-D162 PolarHBondContact O-N 2.87Å; H159-I163 WeakPolarHBondContact O-CG1 3.25Å; H159-I163 PolarHBondContact O-N 3.38Å; H159-I187 HydrophobicContact CB-CD1 4.06Å; H159-I187 HydrophobicContact CB-CG1 4.3Å; H159-E190 IonicContact CD2-OE2 3.7Å; H159-E190 IonicContact CE1-OE2 3.14Å; H159-E190 PolarHBondContact CE1-OE2 3.44Å; H159-E190 IonicContact NE2-OE2 3.84Å; H159-E190 PolarHBondContact NE2-OE2 3.42Å
160	Y	92.6	Very high	91.5	Very high	121 Å²	121	52.1 Å²	52.1	48%	0.475	26%	0.256	S	S	.	.	H	α-helix	trans	-58.3	-45.8	171	173.9	-101.7	0	0	0	111.5	I156 D162 I163 R164	I156-Y160 WeakPolarHBondContact O-CB 3.33Å; I156-Y160 PolarHBondContact O-N 3.41Å; Y160-D162 VanDerWaalsContact C-N 3.34Å; Y160-I163 PolarHBondContact O-N 2.87Å; Y160-R164 HydrophobicContact CD1-CG 4.47Å; Y160-R164 HydrophobicContact CE1-CG 4.09Å; Y160-R164 HydrophobicContact CE2-CG 4.33Å; Y160-R164 WeakPolarHBondContact O-CG 3.37Å; Y160-R164 PolarHBondContact O-N 3.36Å; Y160-R164 PolarHBondContact OH-NE 2.89Å; Y160-R164 PolarHBondContact OH-NH2 3.39Å
161	K	91.7	Very high	90.6	Very high	49 Å²	49	54.9 Å²	54.9	21%	0.213	26%	0.261	C	S	.	.	H	α-helix	trans	-67.7	-32.4	175.9	-67.5	-81.9	-176.5	160.7	0	112.3	L97 D100 K101 L104 A157 F158 H159 L165	L97-K161 HydrophobicContact CD2-CD 3.52Å; D100-K161 IonicContact OD2-NZ 2.66Å; D100-K161 PolarHBondContact OD2-NZ 2.86Å; K101-K161 HydrophobicContact CD-CB 4.18Å; K101-K161 HydrophobicContact CG-CB 3.62Å; L104-K161 HydrophobicContact CD1-CG 3.93Å; A157-K161 WeakPolarHBondContact O-CG 3.35Å; A157-K161 PolarHBondContact O-N 3.02Å; A157-K161 VanDerWaalsContact O-N 3.08Å; F158-K161 PolarHBondContact O-N 3.21Å; H159-K161 VanDerWaalsContact C-N 3.33Å; H159-K161 PolarHBondContact O-N 3.18Å; K161-L165 WeakPolarHBondContact O-CB 3.38Å; K161-L165 PolarHBondContact O-N 3.14Å
162	D	89.7	Confident	88.9	Confident	40 Å²	40	63.5 Å²	63.5	21%	0.214	30%	0.302	C	S	.	.	H	α-helix	trans	-64.2	-46.1	172.8	-168.7	62.3	0	0	0	112.5	K101 F158 H159 Y160 L165 F166 R183	K101-D162 IonicContact NZ-OD1 2.69Å; K101-D162 PolarHBondContact NZ-OD1 3.33Å; F158-D162 PolarHBondContact O-N 3.24Å; H159-D162 WeakPolarHBondContact O-CB 3.3Å; H159-D162 PolarHBondContact O-N 2.87Å; Y160-D162 VanDerWaalsContact C-N 3.34Å; D162-L165 WeakPolarHBondContact O-CB 3.34Å; D162-L165 PolarHBondContact O-N 2.88Å; D162-F166 PolarHBondContact O-N 3.48Å; D162-R183 IonicContact OD2-NH1 3.26Å; D162-R183 PolarHBondContact OD2-NH1 3.44Å
163	I	90.1	Very high	87.8	Confident	33 Å²	33	63.6 Å²	63.6	17%	0.169	30%	0.304	C	S	.	.	H	α-helix	trans	-64.3	-43.6	177.3	-65.7	164.8	0	0	0	110.4	H159 Y160 L165 F166 I167 A178	H159-I163 WeakPolarHBondContact O-CG1 3.25Å; H159-I163 PolarHBondContact O-N 3.38Å; Y160-I163 PolarHBondContact O-N 2.87Å; I163-L165 VanDerWaalsContact C-N 3.3Å; I163-L165 PolarHBondContact O-N 3.4Å; I163-F166 WeakPolarHBondContact O-CB 3.5Å; I163-F166 PolarHBondContact O-N 2.94Å; I163-F166 VanDerWaalsContact O-N 3.14Å; I163-I167 HydrophobicContact CG2-CD1 4.05Å; I163-I167 WeakPolarHBondContact O-CG1 3.39Å; I163-I167 PolarHBondContact O-N 3.41Å; I163-A178 HydrophobicContact CG2-CB 4.06Å
164	R	89.2	Confident	87.1	Confident	123 Å²	123	63.5 Å²	63.5	46%	0.464	30%	0.304	S	S	.	.	H	α-helix	trans	-57.9	-42	174.2	-76.6	-69.7	-161.1	170.9	4.6	112.3	Y160 F166 I167 I168	Y160-R164 HydrophobicContact CD1-CG 4.47Å; Y160-R164 HydrophobicContact CE1-CG 4.09Å; Y160-R164 HydrophobicContact CE2-CG 4.33Å; Y160-R164 WeakPolarHBondContact O-CG 3.37Å; Y160-R164 PolarHBondContact O-N 3.36Å; Y160-R164 PolarHBondContact OH-NE 2.89Å; Y160-R164 PolarHBondContact OH-NH2 3.39Å; R164-F166 VanDerWaalsContact C-N 3.34Å; R164-I167 PolarHBondContact O-N 3.26Å; R164-I168 WeakPolarHBondContact O-CG1 3.5Å; R164-I168 PolarHBondContact O-N 2.94Å; R164-I168 VanDerWaalsContact O-N 3.11Å
165	L	87.7	Confident	86.5	Confident	22 Å²	22	69 Å²	69	12%	0.115	32%	0.324	C	S	.	.	H	α-helix	trans	-62.6	-41.7	175.8	-170.5	72.7	0	0	0	111.5	R94 L97 I98 K101 K161 D162 I163 I167 I168 D169	R94-L165 HydrophobicContact CB-CD1 4.44Å; R94-L165 HydrophobicContact CG-CD1 3.58Å; L97-L165 HydrophobicContact CB-CD1 4.18Å; L97-L165 HydrophobicContact CD1-CD1 4.49Å; I98-L165 HydrophobicContact CD1-CD1 4.47Å; I98-L165 HydrophobicContact CG1-CD1 4.08Å; I98-L165 HydrophobicContact CG1-CD2 4.17Å; K101-L165 HydrophobicContact CD-CD2 4.38Å; K161-L165 WeakPolarHBondContact O-CB 3.38Å; K161-L165 PolarHBondContact O-N 3.14Å; D162-L165 WeakPolarHBondContact O-CB 3.34Å; D162-L165 PolarHBondContact O-N 2.88Å; I163-L165 VanDerWaalsContact C-N 3.3Å; I163-L165 PolarHBondContact O-N 3.4Å; L165-I167 PolarHBondContact O-N 2.83Å; L165-I168 PolarHBondContact O-N 3.14Å; L165-D169 PolarHBondContact O-N 3.34Å
166	F	87.3	Confident	86	Confident	59 Å²	59	77.2 Å²	77.2	26%	0.259	35%	0.354	S	S	.	.	H	α-helix	trans	-63.2	-40.4	177.7	-177.9	-92.9	0	0	0	112.8	D162 I163 R164 D169 H170 A178	D162-F166 PolarHBondContact O-N 3.48Å; I163-F166 WeakPolarHBondContact O-CB 3.5Å; I163-F166 PolarHBondContact O-N 2.94Å; I163-F166 VanDerWaalsContact O-N 3.14Å; R164-F166 VanDerWaalsContact C-N 3.34Å; F166-D169 PolarHBondContact O-N 3.09Å; F166-H170 AromaticContact CD2-CE1 3.79Å; F166-H170 AromaticContact CD2-ND1 3.89Å; F166-H170 AromaticContact CE2-CE1 3.35Å; F166-H170 WeakPolarHBondContact CE2-CE1 3.42Å; F166-H170 AromaticContact CE2-ND1 3.69Å; F166-H170 AromaticContact CZ-CE1 3.7Å; F166-H170 AromaticContact CZ-ND1 3.76Å; F166-H170 PolarHBondContact O-N 2.91Å; F166-H170 PolarHBondContact O-ND1 3.22Å; F166-A178 HydrophobicContact CD1-CB 3.66Å; F166-A178 HydrophobicContact CE1-CB 4.08Å
167	I	87.9	Confident	85.5	Confident	38 Å²	38	78 Å²	78	20%	0.195	36%	0.359	C	S	.	.	H	α-helix	trans	-63	-44.9	176	-65.4	164.1	0	0	0	110.4	I163 R164 L165 D169 H170 K171 W175 A178	I163-I167 HydrophobicContact CG2-CD1 4.05Å; I163-I167 WeakPolarHBondContact O-CG1 3.39Å; I163-I167 PolarHBondContact O-N 3.41Å; R164-I167 PolarHBondContact O-N 3.26Å; L165-I167 PolarHBondContact O-N 2.83Å; I167-D169 VanDerWaalsContact C-N 3.27Å; I167-D169 PolarHBondContact O-N 3.03Å; I167-H170 PolarHBondContact O-N 3.49Å; I167-H170 VanDerWaalsContact O-N 3.17Å; I167-K171 PolarHBondContact O-N 3.23Å; I167-W175 HydrophobicContact CD1-CB 3.84Å; I167-A178 HydrophobicContact CD1-CB 4.36Å; I167-A178 HydrophobicContact CG1-CB 3.84Å
168	I	85.5	Confident	84.9	Confident	41 Å²	41	76.6 Å²	76.6	21%	0.21	35%	0.346	C	S	.	.	H	α-helix	trans	-65.8	-29.6	177.4	-68	163.9	0	0	0	111.7	R90 L97 R164 L165 H170	R90-I168 HydrophobicContact CB-CG2 4.43Å; R90-I168 PolarHBondContact NH2-O 3.25Å; L97-I168 HydrophobicContact CD1-CD1 3.24Å; R164-I168 WeakPolarHBondContact O-CG1 3.5Å; R164-I168 PolarHBondContact O-N 2.94Å; R164-I168 VanDerWaalsContact O-N 3.11Å; L165-I168 PolarHBondContact O-N 3.14Å; I168-H170 VanDerWaalsContact C-N 3.35Å
169	D	83.3	Confident	84.6	Confident	71 Å²	71	78.8 Å²	78.8	38%	0.38	36%	0.358	S	S	.	.	H	α-helix	trans	-74.3	-24.5	176.1	-79	-3.9	0	0	0	112.2	R94 L165 F166 I167	R94-D169 IonicContact CZ-OD1 2.86Å; R94-D169 IonicContact CZ-OD2 3.33Å; R94-D169 IonicContact NE-OD1 3.38Å; R94-D169 PolarHBondContact NE-OD1 2.95Å; R94-D169 IonicContact NE-OD2 3.53Å; R94-D169 IonicContact NH2-OD1 3.63Å; R94-D169 PolarHBondContact NH2-OD1 3.26Å; R94-D169 IonicContact NH2-OD2 2.91Å; R94-D169 PolarHBondContact NH2-OD2 3.28Å; R94-D169 VanDerWaalsContact NH2-OD2 3.14Å; L165-D169 PolarHBondContact O-N 3.34Å; F166-D169 PolarHBondContact O-N 3.09Å; I167-D169 VanDerWaalsContact C-N 3.27Å; I167-D169 PolarHBondContact O-N 3.03Å
170	H	83.8	Confident	84.5	Confident	101 Å²	101	80.9 Å²	80.9	47%	0.468	37%	0.373	S	S	.	.	H	α-helix	trans	-110.1	9.3	-172.2	-66.7	81.8	0	0	0	116.6	F166 I167 I168 E172 V173	F166-H170 AromaticContact CD2-CE1 3.79Å; F166-H170 AromaticContact CD2-ND1 3.89Å; F166-H170 AromaticContact CE2-CE1 3.35Å; F166-H170 WeakPolarHBondContact CE2-CE1 3.42Å; F166-H170 AromaticContact CE2-ND1 3.69Å; F166-H170 AromaticContact CZ-CE1 3.7Å; F166-H170 AromaticContact CZ-ND1 3.76Å; F166-H170 PolarHBondContact O-N 2.91Å; F166-H170 PolarHBondContact O-ND1 3.22Å; I167-H170 PolarHBondContact O-N 3.49Å; I167-H170 VanDerWaalsContact O-N 3.17Å; I168-H170 VanDerWaalsContact C-N 3.35Å; H170-E172 PolarHBondContact O-N 3.46Å; H170-V173 HydrophobicContact CB-CG2 3.67Å
171	K	74.9	Confident	84.4	Confident	112 Å²	112	80.3 Å²	80.3	49%	0.487	39%	0.386	S	S	.	.	S	Bend	trans	55.7	-30	172.6	-48.6	-145.1	165.2	-177.9	0	118.9	D87 R90 I167	D87-K171 WeakPolarHBondContact OD1-CE 3.02Å; D87-K171 IonicContact OD1-NZ 2.61Å; D87-K171 PolarHBondContact OD1-NZ 3.44Å; D87-K171 IonicContact OD2-NZ 2.84Å; D87-K171 PolarHBondContact OD2-NZ 2.93Å; R90-K171 VanDerWaalsContact NH2-CG 3.31Å; I167-K171 PolarHBondContact O-N 3.23Å
172	E	61.1	Low	84.4	Confident	182 Å²	182	84.5 Å²	84.5	85%	0.85	41%	0.406	S	S	*	.	S	Bend	trans	-143.1	31.9	-165.6	-62.5	-166.3	165.1	0	0	114.6	H170	H170-E172 PolarHBondContact O-N 3.46Å
173	V	71.7	Confident	84.5	Confident	35 Å²	35	86.4 Å²	86.4	21%	0.212	41%	0.41	C	S	.	.			trans	-118.8	115.8	-169.3	-166.3	0	0	0	0	110.6	H170 I177	H170-V173 HydrophobicContact CB-CG2 3.67Å; V173-I177 HydrophobicContact CG1-CB 3.37Å; V173-I177 HydrophobicContact CG1-CD1 4.26Å; V173-I177 HydrophobicContact CG1-CG1 4.41Å; V173-I177 HydrophobicContact CG1-CG2 3.36Å
174	D	82.9	Confident	84.6	Confident	114 Å²	114	87.5 Å²	87.5	61%	0.61	42%	0.419	S	S	*	.			trans	-52.4	144.5	168.6	-80.8	-35.9	0	0	0	110.1	R176 I177 A178	D174-R176 PolarHBondContact O-N 2.95Å; D174-I177 HydrophobicContact CB-CD1 4.21Å; D174-I177 HydrophobicContact CB-CG1 4.48Å; D174-I177 PolarHBondContact O-N 3.41Å; D174-A178 PolarHBondContact O-N 3.2Å
175	W	82.3	Confident	84.8	Confident	141 Å²	141	86.8 Å²	86.8	53%	0.534	42%	0.424	S	S	.	.	H	α-helix	trans	-56.5	-24.8	-179.8	71.1	-92.3	0	0	0	112.9	I167 I177 A178 I179	I167-W175 HydrophobicContact CD1-CB 3.84Å; W175-I177 VanDerWaalsContact C-N 3.32Å; W175-A178 PolarHBondContact O-N 3.18Å; W175-I179 HydrophobicContact CE3-CG2 4.36Å; W175-I179 HydrophobicContact CZ3-CG2 4.29Å; W175-I179 PolarHBondContact O-N 2.84Å; W175-I179 VanDerWaalsContact O-N 3.13Å
176	R	86	Confident	85	Confident	173 Å²	173	88.7 Å²	88.7	65%	0.653	44%	0.436	S	S	*	.	H	α-helix	trans	-67.8	-28.6	175.3	-63.9	-178.4	-176.3	-88.7	1.9	113.4	D174 I179	D174-R176 PolarHBondContact O-N 2.95Å; R176-I179 WeakPolarHBondContact O-CG2 3.36Å
177	I	84.5	Confident	85.3	Confident	113 Å²	113	87.3 Å²	87.3	58%	0.579	43%	0.431	S	S	*	.	H	α-helix	trans	-85.9	-30.6	176.5	-59.1	162.4	0	0	0	109.5	V173 D174 W175 I179	V173-I177 HydrophobicContact CG1-CB 3.37Å; V173-I177 HydrophobicContact CG1-CD1 4.26Å; V173-I177 HydrophobicContact CG1-CG1 4.41Å; V173-I177 HydrophobicContact CG1-CG2 3.36Å; D174-I177 HydrophobicContact CB-CD1 4.21Å; D174-I177 HydrophobicContact CB-CG1 4.48Å; D174-I177 PolarHBondContact O-N 3.41Å; W175-I177 VanDerWaalsContact C-N 3.32Å; I177-I179 VanDerWaalsContact C-N 3.27Å; I177-I179 PolarHBondContact O-N 3.36Å
178	A	83.9	Confident	85.6	Confident	2 Å²	2	89.1 Å²	89.1	2%	0.017	44%	0.444	C	S	.	.	H	α-helix	trans	-66.4	-27	172.5	0	0	0	0	0	113.2	I163 F166 I167 D174 W175 T180	I163-A178 HydrophobicContact CG2-CB 4.06Å; F166-A178 HydrophobicContact CD1-CB 3.66Å; F166-A178 HydrophobicContact CE1-CB 4.08Å; I167-A178 HydrophobicContact CD1-CB 4.36Å; I167-A178 HydrophobicContact CG1-CB 3.84Å; D174-A178 PolarHBondContact O-N 3.2Å; W175-A178 PolarHBondContact O-N 3.18Å; A178-T180 PolarHBondContact O-N 3.28Å
179	I	88.4	Confident	86	Confident	65 Å²	65	92.2 Å²	92.2	33%	0.333	46%	0.46	S	S	.	.			trans	-87.9	96	178.9	-159	168.4	0	0	0	111.2	W175 R176 I177 V184	W175-I179 HydrophobicContact CE3-CG2 4.36Å; W175-I179 HydrophobicContact CZ3-CG2 4.29Å; W175-I179 PolarHBondContact O-N 2.84Å; W175-I179 VanDerWaalsContact O-N 3.13Å; R176-I179 WeakPolarHBondContact O-CG2 3.36Å; I177-I179 VanDerWaalsContact C-N 3.27Å; I177-I179 PolarHBondContact O-N 3.36Å; I179-V184 HydrophobicContact CD1-CG2 3.84Å; I179-V184 HydrophobicContact CG1-CG2 3.47Å; I179-V184 VanDerWaalsContact CG1-CG2 3.47Å
180	T	90.4	Very high	86.5	Confident	63 Å²	63	89.3 Å²	89.3	39%	0.387	44%	0.444	S	S	.	.			trans	-89.6	150.2	177.1	56.7	0	0	0	0	111.7	A178 H182 R183 V184	A178-T180 PolarHBondContact O-N 3.28Å; T180-H182 PolarHBondContact O-N 3.25Å; T180-R183 WeakPolarHBondContact O-CB 3.49Å; T180-R183 PolarHBondContact O-N 3.01Å; T180-R183 WeakPolarHBondContact OG1-CB 3.47Å; T180-R183 WeakPolarHBondContact OG1-CD 3.37Å; T180-R183 WeakPolarHBondContact OG1-CG 3.36Å; T180-R183 PolarHBondContact OG1-N 3.47Å; T180-V184 PolarHBondContact O-N 3.07Å
181	S	90.8	Very high	87	Confident	109 Å²	109	86.4 Å²	86.4	76%	0.762	43%	0.432	S	S	*	.	H	α-helix	trans	-55.8	-38.2	179	-47.9	0	0	0	0	112.5	V184 L185	S181-V184 PolarHBondContact O-N 3.01Å; S181-L185 WeakPolarHBondContact O-CB 3.39Å; S181-L185 PolarHBondContact O-N 3.49Å
182	H	91.8	Very high	87.9	Confident	137 Å²	137	86.2 Å²	86.2	63%	0.634	44%	0.436	S	S	*	.	H	α-helix	trans	-63.3	-43.2	175	179.8	-87.2	0	0	0	112.3	T180 L185 V186	T180-H182 PolarHBondContact O-N 3.25Å; H182-L185 PolarHBondContact O-N 3.45Å; H182-V186 WeakPolarHBondContact O-CG2 3.3Å; H182-V186 PolarHBondContact O-N 2.91Å
183	R	90.9	Very high	89.4	Confident	80 Å²	80	78.9 Å²	78.9	30%	0.302	40%	0.404	S	S	.	.	H	α-helix	trans	-63.1	-43.6	176.1	-75.7	175.2	-176.6	-89.7	3.4	111.2	D162 T180 L185 V186 I187	D162-R183 IonicContact OD2-NH1 3.26Å; D162-R183 PolarHBondContact OD2-NH1 3.44Å; T180-R183 WeakPolarHBondContact O-CB 3.49Å; T180-R183 PolarHBondContact O-N 3.01Å; T180-R183 WeakPolarHBondContact OG1-CB 3.47Å; T180-R183 WeakPolarHBondContact OG1-CD 3.37Å; T180-R183 WeakPolarHBondContact OG1-CG 3.36Å; T180-R183 PolarHBondContact OG1-N 3.47Å; R183-L185 VanDerWaalsContact C-N 3.34Å; R183-L185 PolarHBondContact O-N 3.29Å; R183-V186 PolarHBondContact O-N 2.85Å; R183-I187 WeakPolarHBondContact O-CG1 3.33Å; R183-I187 PolarHBondContact O-N 3.42Å
184	V	92.1	Very high	90.3	Very high	57 Å²	57	77.2 Å²	77.2	35%	0.345	39%	0.393	S	S	.	.	H	α-helix	trans	-62.4	-41.7	177.2	178.6	0	0	0	0	111.2	I179 T180 S181 V186 I187 T188	I179-V184 HydrophobicContact CD1-CG2 3.84Å; I179-V184 HydrophobicContact CG1-CG2 3.47Å; I179-V184 VanDerWaalsContact CG1-CG2 3.47Å; T180-V184 PolarHBondContact O-N 3.07Å; S181-V184 PolarHBondContact O-N 3.01Å; V184-V186 PolarHBondContact O-N 3.38Å; V184-I187 PolarHBondContact O-N 3.33Å; V184-T188 HydrophobicContact CG1-CG2 4.17Å; V184-T188 WeakPolarHBondContact O-CB 3.47Å; V184-T188 VanDerWaalsContact O-CG2 3.28Å; V184-T188 WeakPolarHBondContact O-CG2 3.46Å; V184-T188 PolarHBondContact O-N 3.4Å; V184-T188 PolarHBondContact O-OG1 3.35Å
185	L	93.2	Very high	90.7	Very high	108 Å²	108	75.4 Å²	75.4	57%	0.565	39%	0.386	S	S	*	.	H	α-helix	trans	-59.4	-46.5	175	-170.7	161.8	0	0	0	111.3	S181 H182 R183 I187 T188 L189	S181-L185 WeakPolarHBondContact O-CB 3.39Å; S181-L185 PolarHBondContact O-N 3.49Å; H182-L185 PolarHBondContact O-N 3.45Å; R183-L185 VanDerWaalsContact C-N 3.34Å; R183-L185 PolarHBondContact O-N 3.29Å; L185-I187 PolarHBondContact O-N 3.18Å; L185-T188 WeakPolarHBondContact CA-OG1 3.38Å; L185-T188 PolarHBondContact O-N 3.19Å; L185-T188 PolarHBondContact O-OG1 3.47Å; L185-L189 WeakPolarHBondContact O-CB 3.25Å; L185-L189 PolarHBondContact O-N 3.29Å
186	V	93.4	Very high	91.1	Very high	62 Å²	62	70.6 Å²	70.6	38%	0.376	37%	0.37	S	S	.	.	H	α-helix	trans	-63.4	-43	177.7	173.7	0	0	0	0	111.7	H182 R183 V184 L189 E190	H182-V186 WeakPolarHBondContact O-CG2 3.3Å; H182-V186 PolarHBondContact O-N 2.91Å; R183-V186 PolarHBondContact O-N 2.85Å; V184-V186 PolarHBondContact O-N 3.38Å; V186-L189 PolarHBondContact O-N 2.99Å; V186-E190 VanDerWaalsContact O-CB 3.32Å; V186-E190 WeakPolarHBondContact O-CB 3.49Å; V186-E190 PolarHBondContact O-N 2.87Å
187	I	93.7	Very high	91.2	Very high	30 Å²	30	63.6 Å²	63.6	15%	0.154	35%	0.345	C	S	.	.	H	α-helix	trans	-63.2	-44.7	177.8	-66	165.6	0	0	0	110.7	H159 R183 V184 L185 E190 L191	H159-I187 HydrophobicContact CB-CD1 4.06Å; H159-I187 HydrophobicContact CB-CG1 4.3Å; R183-I187 WeakPolarHBondContact O-CG1 3.33Å; R183-I187 PolarHBondContact O-N 3.42Å; V184-I187 PolarHBondContact O-N 3.33Å; L185-I187 PolarHBondContact O-N 3.18Å; I187-E190 WeakPolarHBondContact O-CB 3.2Å; I187-E190 PolarHBondContact O-N 2.84Å; I187-L191 HydrophobicContact CG2-CD1 4.01Å; I187-L191 HydrophobicContact CG2-CG 4.4Å; I187-L191 VanDerWaalsContact O-CG 3.31Å; I187-L191 WeakPolarHBondContact O-CG 3.3Å; I187-L191 PolarHBondContact O-N 2.98Å
188	T	93.7	Very high	90.8	Very high	75 Å²	75	58.3 Å²	58.3	46%	0.46	32%	0.318	S	S	.	.	H	α-helix	trans	-66.4	-41.1	179.8	50	0	0	0	0	112.1	V184 L185 E190 L191 L192	V184-T188 HydrophobicContact CG1-CG2 4.17Å; V184-T188 WeakPolarHBondContact O-CB 3.47Å; V184-T188 VanDerWaalsContact O-CG2 3.28Å; V184-T188 WeakPolarHBondContact O-CG2 3.46Å; V184-T188 PolarHBondContact O-N 3.4Å; V184-T188 PolarHBondContact O-OG1 3.35Å; L185-T188 WeakPolarHBondContact CA-OG1 3.38Å; L185-T188 PolarHBondContact O-N 3.19Å; L185-T188 PolarHBondContact O-OG1 3.47Å; T188-E190 VanDerWaalsContact C-N 3.32Å; T188-E190 PolarHBondContact O-N 2.98Å; T188-L191 PolarHBondContact O-N 3.33Å; T188-L192 WeakPolarHBondContact O-CB 3.25Å; T188-L192 PolarHBondContact O-N 3.05Å
189	L	93.3	Very high	90.1	Very high	106 Å²	106	61.4 Å²	61.4	56%	0.555	34%	0.337	S	S	*	.	H	α-helix	trans	-59.8	-44.2	171.9	-172.2	89.8	0	0	0	111.1	L185 V186 L192 V193	L185-L189 WeakPolarHBondContact O-CB 3.25Å; L185-L189 PolarHBondContact O-N 3.29Å; V186-L189 PolarHBondContact O-N 2.99Å; L189-L192 PolarHBondContact O-N 3.27Å; L189-V193 WeakPolarHBondContact O-CG2 3.47Å; L189-V193 PolarHBondContact O-N 3.43Å
190	E	94.8	Very high	88.6	Confident	10 Å²	10	60 Å²	60	5%	0.047	34%	0.338	C	S	.	.	H	α-helix	trans	-62.9	-45.9	179.7	-169.8	176	174.3	0	0	112	I155 H159 V186 I187 T188 L192 V193 C194 Y243 R247	I155-E190 HydrophobicContact CG2-CG 4.27Å; H159-E190 IonicContact CD2-OE2 3.7Å; H159-E190 IonicContact CE1-OE2 3.14Å; H159-E190 PolarHBondContact CE1-OE2 3.44Å; H159-E190 IonicContact NE2-OE2 3.84Å; H159-E190 PolarHBondContact NE2-OE2 3.42Å; V186-E190 VanDerWaalsContact O-CB 3.32Å; V186-E190 WeakPolarHBondContact O-CB 3.49Å; V186-E190 PolarHBondContact O-N 2.87Å; I187-E190 WeakPolarHBondContact O-CB 3.2Å; I187-E190 PolarHBondContact O-N 2.84Å; T188-E190 VanDerWaalsContact C-N 3.32Å; T188-E190 PolarHBondContact O-N 2.98Å; E190-L192 VanDerWaalsContact C-N 3.32Å; E190-L192 PolarHBondContact O-N 2.9Å; E190-V193 PolarHBondContact O-N 2.87Å; E190-C194 PolarHBondContact O-N 3.39Å; E190-Y243 VanDerWaalsContact CD-OH 3.25Å; E190-Y243 HydrophobicContact CG-CE2 4.06Å; E190-Y243 WeakPolarHBondContact CG-OH 3.46Å; E190-Y243 WeakPolarHBondContact OE1-CE2 3.33Å; E190-Y243 PolarHBondContact OE1-OH 3.1Å; E190-R247 IonicContact OE1-CZ 3.45Å; E190-R247 IonicContact OE1-NH1 3.91Å; E190-R247 PolarHBondContact OE1-NH1 3.36Å; E190-R247 IonicContact OE1-NH2 2.75Å; E190-R247 PolarHBondContact OE1-NH2 3.42Å; E190-R247 IonicContact OE2-CZ 3.41Å; E190-R247 IonicContact OE2-NH1 3.46Å; E190-R247 PolarHBondContact OE2-NH1 3.17Å; E190-R247 IonicContact OE2-NH2 2.81Å; E190-R247 PolarHBondContact OE2-NH2 2.97Å
191	L	93.9	Very high	86.8	Confident	40 Å²	40	58.8 Å²	58.8	21%	0.209	33%	0.332	C	S	.	.	H	α-helix	trans	-61.7	-41.8	174.4	-68.2	172.6	0	0	0	111	L152 I155 I156 I187 T188 V193 C194 V195	L152-L191 HydrophobicContact CD2-CB 4.41Å; L152-L191 HydrophobicContact CD2-CD2 3.71Å; I155-L191 HydrophobicContact CB-CD2 4.28Å; I155-L191 HydrophobicContact CG2-CD2 3.88Å; I156-L191 HydrophobicContact CD1-CD2 4.44Å; I156-L191 HydrophobicContact CG1-CD1 4.37Å; I156-L191 HydrophobicContact CG1-CD2 3.98Å; I187-L191 HydrophobicContact CG2-CD1 4.01Å; I187-L191 HydrophobicContact CG2-CG 4.4Å; I187-L191 VanDerWaalsContact O-CG 3.31Å; I187-L191 WeakPolarHBondContact O-CG 3.3Å; I187-L191 PolarHBondContact O-N 2.98Å; T188-L191 PolarHBondContact O-N 3.33Å; L191-V193 PolarHBondContact O-N 3.37Å; L191-C194 CarbonylContact O-C 3.48Å; L191-C194 PolarHBondContact O-N 3.46Å; L191-C194 VanDerWaalsContact O-N 3.13Å; L191-V195 WeakPolarHBondContact O-CB 3.39Å; L191-V195 WeakPolarHBondContact O-CG2 3.43Å; L191-V195 PolarHBondContact O-N 3.36Å
192	L	92.6	Very high	84.9	Confident	109 Å²	109	56.8 Å²	56.8	57%	0.571	31%	0.309	S	S	*	.	H	α-helix	trans	-60.2	-45.3	177.7	-176.1	139.3	0	0	0	111.8	T188 L189 E190 C194 V195 I196	T188-L192 WeakPolarHBondContact O-CB 3.25Å; T188-L192 PolarHBondContact O-N 3.05Å; L189-L192 PolarHBondContact O-N 3.27Å; E190-L192 VanDerWaalsContact C-N 3.32Å; E190-L192 PolarHBondContact O-N 2.9Å; L192-C194 VanDerWaalsContact C-N 3.28Å; L192-C194 PolarHBondContact O-N 3.39Å; L192-V195 PolarHBondContact O-N 2.92Å; L192-I196 HydrophobicContact CD2-CD1 4.22Å; L192-I196 VanDerWaalsContact O-CG1 3.31Å; L192-I196 WeakPolarHBondContact O-CG1 3.38Å; L192-I196 PolarHBondContact O-N 3.43Å
193	V	92.9	Very high	82.7	Confident	28 Å²	28	60 Å²	60	17%	0.17	32%	0.315	C	S	.	.	H	α-helix	trans	-61.4	-37.2	175.3	172.9	0	0	0	0	111.7	L189 E190 L191 L240 Y243	L189-V193 WeakPolarHBondContact O-CG2 3.47Å; L189-V193 PolarHBondContact O-N 3.43Å; E190-V193 PolarHBondContact O-N 2.87Å; L191-V193 PolarHBondContact O-N 3.37Å; V193-L240 HydrophobicContact CG1-CB 3.66Å; V193-L240 HydrophobicContact CG1-CD1 4.39Å; V193-Y243 HydrophobicContact CG1-CD1 4.3Å; V193-Y243 HydrophobicContact CG1-CE1 4.11Å
194	C	91.3	Very high	80.8	Confident	0 Å²	0	60.5 Å²	60.5	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-82.4	-21.9	-179.5	-71.1	0	0	0	0	114.6	L151 L152 I155 E190 L191 L192 I196 R241 Y243	L151-C194 HydrophobicContact CD2-CB 4.16Å; L152-C194 HydrophobicContact CD2-CB 3.72Å; I155-C194 HydrophobicContact CD1-CB 3.78Å; I155-C194 WeakPolarHBondContact CD1-SG 3.36Å; E190-C194 PolarHBondContact O-N 3.39Å; L191-C194 CarbonylContact O-C 3.48Å; L191-C194 PolarHBondContact O-N 3.46Å; L191-C194 VanDerWaalsContact O-N 3.13Å; L192-C194 VanDerWaalsContact C-N 3.28Å; L192-C194 PolarHBondContact O-N 3.39Å; C194-I196 VanDerWaalsContact C-N 3.33Å; C194-R241 PolarHBondContact O-NH2 3.04Å; C194-Y243 PolarHBondContact SG-OH 2.93Å
195	V	91.8	Very high	78.6	Confident	75 Å²	75	61.4 Å²	61.4	46%	0.455	33%	0.327	S	S	.	.	H	α-helix	trans	-72	-29.1	174.6	166.2	0	0	0	0	111.3	L152 L191 L192 H197	L152-V195 HydrophobicContact CD1-CG2 3.58Å; L152-V195 HydrophobicContact CD2-CG2 3.77Å; L152-V195 HydrophobicContact CG-CG2 4.33Å; L191-V195 WeakPolarHBondContact O-CB 3.39Å; L191-V195 WeakPolarHBondContact O-CG2 3.43Å; L191-V195 PolarHBondContact O-N 3.36Å; L192-V195 PolarHBondContact O-N 2.92Å; V195-H197 PolarHBondContact O-N 3.35Å; V195-H197 VanDerWaalsContact O-N 3.11Å; V195-H197 PolarHBondContact O-ND1 3.16Å
196	I	89.3	Confident	76.2	Confident	40 Å²	40	61.9 Å²	61.9	21%	0.205	33%	0.329	C	S	.	.			trans	-63.4	111.9	-179.5	-69.4	168.2	0	0	0	109.7	L192 C194 L234 L237 M238 R241	L192-I196 HydrophobicContact CD2-CD1 4.22Å; L192-I196 VanDerWaalsContact O-CG1 3.31Å; L192-I196 WeakPolarHBondContact O-CG1 3.38Å; L192-I196 PolarHBondContact O-N 3.43Å; C194-I196 VanDerWaalsContact C-N 3.33Å; I196-L234 HydrophobicContact CB-CD1 4.16Å; I196-L234 HydrophobicContact CG2-CD1 3.26Å; I196-L237 HydrophobicContact CG2-CB 3.49Å; I196-L237 VanDerWaalsContact CG2-CB 3.49Å; I196-L237 HydrophobicContact CG2-CD1 3.94Å; I196-L237 HydrophobicContact CG2-CG 4.37Å; I196-M238 WeakPolarHBondContact O-CG 3.07Å; I196-R241 PolarHBondContact O-NH2 3.14Å
197	H	87.8	Confident	73.9	Confident	26 Å²	26	64.1 Å²	64.1	12%	0.12	34%	0.339	C	S	.	.			trans	-155.2	154.6	172.3	62.1	-71	0	0	0	111.2	I144 S145 T148 V195 V199 L234 M238	I144-H197 HydrophobicContact CG2-CB 4.27Å; S145-H197 PolarHBondContact OG-NE2 3.47Å; T148-H197 HydrophobicContact CG2-CB 3.75Å; T148-H197 PolarHBondContact OG1-CE1 2.93Å; V195-H197 PolarHBondContact O-N 3.35Å; V195-H197 VanDerWaalsContact O-N 3.11Å; V195-H197 PolarHBondContact O-ND1 3.16Å; H197-V199 VanDerWaalsContact CD2-CG2 3.43Å; H197-V199 WeakPolarHBondContact CD2-CG2 3.28Å; H197-V199 WeakPolarHBondContact NE2-CG2 3.42Å; H197-V199 WeakPolarHBondContact O-CG2 3.5Å; H197-V199 PolarHBondContact O-N 3.01Å; H197-L234 WeakPolarHBondContact O-CD1 3.3Å; H197-L234 WeakPolarHBondContact O-CD2 3.45Å; H197-L234 VanDerWaalsContact O-CG 3.31Å; H197-L234 WeakPolarHBondContact O-CG 3.35Å; H197-M238 HydrophobicContact CB-CG 4.37Å; H197-M238 HydrophobicContact CB-SD 3.49Å; H197-M238 WeakPolarHBondContact CB-SD 3.46Å
198	P	77.9	Confident	71.6	Confident	2 Å²	2	71.5 Å²	71.5	1%	0.013	37%	0.366	C	S	.	.			trans	-68.2	105.7	180	26.8	-33.1	0	0	0	110.5	M119 E231 L234 M238	M119-P198 HydrophobicContact CG-CG 4.41Å; P198-E231 HydrophobicContact CB-CG 3.97Å; P198-L234 HydrophobicContact CB-CD2 4.5Å; P198-L234 HydrophobicContact CB-CG 4.38Å; P198-M238 HydrophobicContact CG-CE 3.93Å
199	V	68.6	Low	69	Low	67 Å²	67	71.5 Å²	71.5	41%	0.406	37%	0.374	S	S	.	.			trans	-101.3	0.1	177.5	-178.7	0	0	0	0	111.2	H197 S201 Y202	H197-V199 VanDerWaalsContact CD2-CG2 3.43Å; H197-V199 WeakPolarHBondContact CD2-CG2 3.28Å; H197-V199 WeakPolarHBondContact NE2-CG2 3.42Å; H197-V199 WeakPolarHBondContact O-CG2 3.5Å; H197-V199 PolarHBondContact O-N 3.01Å; V199-S201 VanDerWaalsContact C-N 3.29Å; V199-S201 PolarHBondContact O-N 3.23Å; V199-Y202 HydrophobicContact CG1-CD2 3.97Å; V199-Y202 WeakPolarHBondContact O-CD2 3.48Å; V199-Y202 PolarHBondContact O-N 3.41Å
200	G	56.4	Low	66.7	Low	35 Å²	35	73 Å²	73	36%	0.361	38%	0.382	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.6	-24.2	-160.8	0	0	0	0	0	117.3	Y202	G200-Y202 PolarHBondContact O-N 3.28Å
201	S	53.2	Low	64	Low	38 Å²	38	76.2 Å²	76.2	27%	0.266	41%	0.406	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.3	-7.3	-175.5	77.2	0	0	0	0	115.2	N141 V199	N141-S201 PolarHBondContact ND2-OG 2.99Å; V199-S201 VanDerWaalsContact C-N 3.29Å; V199-S201 PolarHBondContact O-N 3.23Å
202	Y	50.1	Low	61.3	Low	68 Å²	68	80.3 Å²	80.3	27%	0.267	44%	0.438	S	S	.	.	H	α-helix	trans	-80.1	-25.9	-178	-74.8	-75.2	0	0	0	113.9	N141 C142 V199 G200 E204	N141-Y202 HydrophobicContact CB-CE2 3.97Å; N141-Y202 PolarHBondContact O-OH 3.43Å; C142-Y202 WeakPolarHBondContact CA-OH 3.41Å; C142-Y202 WeakPolarHBondContact CB-OH 3.32Å; C142-Y202 PolarHBondContact N-OH 2.93Å; C142-Y202 PolarHBondContact SG-OH 3.39Å; V199-Y202 HydrophobicContact CG1-CD2 3.97Å; V199-Y202 WeakPolarHBondContact O-CD2 3.48Å; V199-Y202 PolarHBondContact O-N 3.41Å; G200-Y202 PolarHBondContact O-N 3.28Å; Y202-E204 VanDerWaalsContact C-N 3.34Å
203	W	44.9	Very low	58.4	Low	203 Å²	203	80 Å²	80	77%	0.769	44%	0.444	S	S	*	.	H	α-helix	trans	-73.6	-29.5	-173.6	-155.8	-95.5	0	0	0	112.3
204	E	51	Low	55.4	Low	92 Å²	92	83.4 Å²	83.4	43%	0.43	48%	0.476	S	S	.	.	H	α-helix	trans	-69.4	-40.7	177.5	-65.7	-169.1	164.2	0	0	112.1	Y202 N206 L207 Y208	Y202-E204 VanDerWaalsContact C-N 3.34Å; E204-N206 VanDerWaalsContact C-N 3.31Å; E204-N206 PolarHBondContact O-N 2.95Å; E204-L207 PolarHBondContact O-N 3.47Å; E204-L207 VanDerWaalsContact O-N 3.12Å; E204-Y208 HydrophobicContact CB-CD2 4.3Å; E204-Y208 HydrophobicContact CB-CE2 4.34Å; E204-Y208 WeakPolarHBondContact O-CD2 3.42Å; E204-Y208 PolarHBondContact O-N 3.39Å
205	V	46.2	Very low	52.5	Low	76 Å²	76	87.8 Å²	87.8	46%	0.461	51%	0.512	S	S	.	.	H	α-helix	trans	-63.5	-35.5	-176.9	179.7	0	0	0	0	112.3	A209	V205-A209 WeakPolarHBondContact O-CB 3.33Å; V205-A209 PolarHBondContact O-N 3.34Å; V205-A209 VanDerWaalsContact O-N 3.1Å
206	N	43.1	Very low	50.5	Low	117 Å²	117	89.6 Å²	89.6	63%	0.626	53%	0.525	S	S	*	.	H	α-helix	trans	-76.6	-22.6	177.3	-99.5	-25.7	0	0	0	113.8	E204	E204-N206 VanDerWaalsContact C-N 3.31Å; E204-N206 PolarHBondContact O-N 2.95Å
207	L	44.6	Very low	47.5	Very low	109 Å²	109	94.7 Å²	94.7	57%	0.571	55%	0.552	S	S	*	*	H	α-helix	trans	-80.2	-37.9	173.1	-112.1	93	0	0	0	111.9	E204 S211	E204-L207 PolarHBondContact O-N 3.47Å; E204-L207 VanDerWaalsContact O-N 3.12Å; L207-S211 PolarHBondContact O-OG 3.1Å
208	Y	46.6	Very low	44.7	Very low	186 Å²	186	99.9 Å²	99.9	73%	0.729	59%	0.59	S	S	*	*	H	α-helix	trans	-76.8	-26.5	179.1	-76.4	-72.9	0	0	0	113.6	E204	E204-Y208 HydrophobicContact CB-CD2 4.3Å; E204-Y208 HydrophobicContact CB-CE2 4.34Å; E204-Y208 WeakPolarHBondContact O-CD2 3.42Å; E204-Y208 PolarHBondContact O-N 3.39Å
209	A	39.4	Very low	42.3	Very low	75 Å²	75	106.1 Å²	106.1	62%	0.62	62%	0.622	S	S	*	*	H	α-helix	trans	-75	-23.8	177.4	0	0	0	0	0	114.1	V205	V205-A209 WeakPolarHBondContact O-CB 3.33Å; V205-A209 PolarHBondContact O-N 3.34Å; V205-A209 VanDerWaalsContact O-N 3.1Å
210	N	44	Very low	40.4	Very low	138 Å²	138	105.7 Å²	105.7	74%	0.738	62%	0.622	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.9	1.5	-177.7	-76.6	-9.8	0	0	0	114.1
211	S	37.3	Very low	39.4	Very low	76 Å²	76	108.2 Å²	108.2	53%	0.531	63%	0.634	S	S	.	*			trans	-122.1	78.5	-174.6	-52.6	0	0	0	0	110.9	L207 S213	L207-S211 PolarHBondContact O-OG 3.1Å; S211-S213 PolarHBondContact O-N 3.41Å
212	S	37.8	Very low	38.5	Very low	127 Å²	127	113 Å²	113	89%	0.888	65%	0.652	S	S	*	*			trans	-72.2	76.4	160.1	59.1	0	0	0	0	109.9
213	S	31.8	Very low	38.1	Very low	101 Å²	101	116.6 Å²	116.6	71%	0.706	67%	0.671	S	S	*	*			trans	-157	124.8	162.4	62.3	0	0	0	0	110.9	S211	S211-S213 PolarHBondContact O-N 3.41Å
214	A	29.8	Very low	38.5	Very low	100 Å²	100	112.4 Å²	112.4	83%	0.826	66%	0.664	S	S	*	*			trans	-64	130.8	-179.2	0	0	0	0	0	112.8
215	A	31	Very low	38.8	Very low	93 Å²	93	112.9 Å²	112.9	77%	0.769	66%	0.664	S	S	*	*			trans	62.1	168.5	150.1	0	0	0	0	0	118.8
216	P	48.7	Very low	39.3	Very low	113 Å²	113	111.8 Å²	111.8	73%	0.734	66%	0.663	S	S	*	*				-123.7	143.5	-51.4	32.9	-20.1	0	0	0	108.8
217	L	27.5	Very low	40.1	Very low	146 Å²	146	110.3 Å²	110.3	76%	0.764	66%	0.655	S	S	*	*			trans	-151.6	112.1	169.2	-119	123.9	0	0	0	114.1	I219	L217-I219 HydrophobicContact CB-CD1 4.19Å; L217-I219 HydrophobicContact CB-CG1 4.08Å; L217-I219 HydrophobicContact CD2-CD1 3.93Å; L217-I219 HydrophobicContact CD2-CG1 3.57Å; L217-I219 HydrophobicContact CG-CG1 4.45Å; L217-I219 PolarHBondContact O-N 3.15Å
218	C	28.8	Very low	41	Very low	136 Å²	136	109.9 Å²	109.9	92%	0.919	65%	0.653	S	S	*	*			trans	-49	84.3	152.3	-52.7	0	0	0	0	109.7
219	I	27.4	Very low	42.1	Very low	132 Å²	132	104.4 Å²	104.4	68%	0.677	64%	0.636	S	S	*	*			trans	-108.2	98.5	166.8	-66	171.7	0	0	0	107.1	L217	L217-I219 HydrophobicContact CB-CD1 4.19Å; L217-I219 HydrophobicContact CB-CG1 4.08Å; L217-I219 HydrophobicContact CD2-CD1 3.93Å; L217-I219 HydrophobicContact CD2-CG1 3.57Å; L217-I219 HydrophobicContact CG-CG1 4.45Å; L217-I219 PolarHBondContact O-N 3.15Å
220	S	28.3	Very low	43.7	Very low	58 Å²	58	106.9 Å²	106.9	41%	0.406	64%	0.636	S	S	.	*			trans	57.8	94.5	151.7	-164.8	0	0	0	0	118.3	H222 H223	S220-H222 PolarHBondContact O-N 3.21Å; S220-H222 VanDerWaalsContact OG-CB 3.3Å; S220-H222 WeakPolarHBondContact OG-CB 3.41Å; S220-H222 PolarHBondContact OG-N 3.07Å; S220-H223 PolarHBondContact O-N 3.4Å
221	S	35.9	Very low	45.2	Very low	88 Å²	88	102.6 Å²	102.6	62%	0.615	61%	0.612	S	S	*	*	T	Hydrogen-bonded Turn	trans	-56.1	2.8	157.9	59.9	0	0	0	0	115.2	K225	S221-K225 WeakPolarHBondContact O-CD 3.46Å
222	H	35.2	Very low	47	Very low	138 Å²	138	101.1 Å²	101.1	64%	0.639	60%	0.597	S	S	*	*	T	Hydrogen-bonded Turn	trans	-95.9	-24	174.7	-115.4	-79	0	0	0	113.2	S220	S220-H222 PolarHBondContact O-N 3.21Å; S220-H222 VanDerWaalsContact OG-CB 3.3Å; S220-H222 WeakPolarHBondContact OG-CB 3.41Å; S220-H222 PolarHBondContact OG-N 3.07Å
223	H	41.6	Very low	49.1	Very low	145 Å²	145	99.7 Å²	99.7	67%	0.671	58%	0.579	S	S	*	*	H	α-helix	trans	-79.9	-37.4	176.8	-106.7	28.3	0	0	0	112.5	S220 K225 A226 L227	S220-H223 PolarHBondContact O-N 3.4Å; H223-K225 VanDerWaalsContact C-N 3.28Å; H223-K225 PolarHBondContact O-N 2.85Å; H223-A226 PolarHBondContact O-N 2.92Å; H223-L227 WeakPolarHBondContact O-CB 3.2Å; H223-L227 PolarHBondContact O-N 3.36Å; H223-L227 VanDerWaalsContact O-N 3.11Å
224	D	52.6	Low	51.6	Low	115 Å²	115	97.1 Å²	97.1	62%	0.615	56%	0.557	S	S	*	*	H	α-helix	trans	-60	-37.5	174.5	-77.6	-19.8	0	0	0	112.7	L228	D224-L228 VanDerWaalsContact O-CB 3.29Å; D224-L228 WeakPolarHBondContact O-CB 3.41Å; D224-L228 PolarHBondContact O-N 3.14Å; D224-L228 VanDerWaalsContact O-N 3.09Å
225	K	56.6	Low	54.1	Low	101 Å²	101	92.7 Å²	92.7	44%	0.439	52%	0.52	S	S	.	.	H	α-helix	trans	-68.2	-41.9	-178.5	-71.8	176	-176.9	165.5	0	112.4	S221 H223 D229	S221-K225 WeakPolarHBondContact O-CD 3.46Å; H223-K225 VanDerWaalsContact C-N 3.28Å; H223-K225 PolarHBondContact O-N 2.85Å; K225-D229 WeakPolarHBondContact O-CB 3.32Å; K225-D229 PolarHBondContact O-N 3.37Å; K225-D229 VanDerWaalsContact O-N 3.09Å; K225-D229 VanDerWaalsContact O-OD2 3.12Å
226	A	57.7	Low	56.6	Low	53 Å²	53	90 Å²	90	44%	0.438	49%	0.492	S	S	.	.	H	α-helix	trans	-72.8	-37.1	-179.5	0	0	0	0	0	111.8	H223 D229 M230	H223-A226 PolarHBondContact O-N 2.92Å; A226-D229 PolarHBondContact O-N 3.44Å; A226-M230 WeakPolarHBondContact O-CG 3.45Å; A226-M230 PolarHBondContact O-N 2.85Å
227	L	60.3	Low	58.5	Low	86 Å²	86	87.3 Å²	87.3	45%	0.45	47%	0.472	S	S	.	.	H	α-helix	trans	-67.3	-41.7	178	-161.1	152.5	0	0	0	111.2	H223 M230 E231	H223-L227 WeakPolarHBondContact O-CB 3.2Å; H223-L227 PolarHBondContact O-N 3.36Å; H223-L227 VanDerWaalsContact O-N 3.11Å; L227-M230 PolarHBondContact O-N 3.46Å; L227-E231 PolarHBondContact O-N 3.14Å
228	L	63.5	Low	61.4	Low	101 Å²	101	80.4 Å²	80.4	53%	0.529	44%	0.435	S	S	.	.	H	α-helix	trans	-66.1	-39	175	-164	73.4	0	0	0	112.6	D224 M230 E231 L232	D224-L228 VanDerWaalsContact O-CB 3.29Å; D224-L228 WeakPolarHBondContact O-CB 3.41Å; D224-L228 PolarHBondContact O-N 3.14Å; D224-L228 VanDerWaalsContact O-N 3.09Å; L228-M230 VanDerWaalsContact C-N 3.29Å; L228-M230 PolarHBondContact O-N 2.99Å; L228-E231 PolarHBondContact O-N 3Å; L228-L232 WeakPolarHBondContact O-CB 3.46Å; L228-L232 PolarHBondContact O-N 3.21Å
229	D	69.6	Low	64.3	Low	70 Å²	70	74.9 Å²	74.9	37%	0.374	40%	0.396	S	S	.	.	H	α-helix	trans	-66.4	-32.4	175.2	-72.7	-24.6	0	0	0	111.9	K225 A226 L233 R311	K225-D229 WeakPolarHBondContact O-CB 3.32Å; K225-D229 PolarHBondContact O-N 3.37Å; K225-D229 VanDerWaalsContact O-N 3.09Å; K225-D229 VanDerWaalsContact O-OD2 3.12Å; A226-D229 PolarHBondContact O-N 3.44Å; D229-L233 WeakPolarHBondContact O-CB 3.5Å; D229-L233 PolarHBondContact O-N 2.84Å; D229-R311 VanDerWaalsContact CG-NH1 3.3Å; D229-R311 IonicContact OD1-CZ 2.73Å; D229-R311 IonicContact OD1-NH1 3.32Å; D229-R311 PolarHBondContact OD1-NH1 2.7Å; D229-R311 IonicContact OD2-NH1 3.01Å; D229-R311 PolarHBondContact OD2-NH1 2.96Å
230	M	72.3	Confident	67.2	Low	127 Å²	127	72.7 Å²	72.7	63%	0.626	39%	0.385	S	S	*	.	H	α-helix	trans	-72.8	-38.5	173.8	-69.3	-67.1	-85.7	0	0	112	A226 L227 L228 L232 L233 L234	A226-M230 WeakPolarHBondContact O-CG 3.45Å; A226-M230 PolarHBondContact O-N 2.85Å; L227-M230 PolarHBondContact O-N 3.46Å; L228-M230 VanDerWaalsContact C-N 3.29Å; L228-M230 PolarHBondContact O-N 2.99Å; M230-L232 VanDerWaalsContact C-N 3.35Å; M230-L233 PolarHBondContact O-N 3.13Å; M230-L234 WeakPolarHBondContact O-CB 3.34Å; M230-L234 PolarHBondContact O-N 2.85Å
231	E	74.7	Confident	70.3	Confident	48 Å²	48	70 Å²	70	22%	0.224	37%	0.366	C	S	.	.	H	α-helix	trans	-64.6	-39.7	173.9	-172.2	178.9	176.9	0	0	112	H122 P198 L227 L228 L234 S235	H122-E231 IonicContact CE1-OE1 2.75Å; P198-E231 HydrophobicContact CB-CG 3.97Å; L227-E231 PolarHBondContact O-N 3.14Å; L228-E231 PolarHBondContact O-N 3Å; E231-L234 PolarHBondContact O-N 2.72Å; E231-S235 WeakPolarHBondContact O-CB 3.28Å; E231-S235 PolarHBondContact O-N 3.13Å; E231-S235 PolarHBondContact O-OG 3.32Å
232	L	77	Confident	72.9	Confident	45 Å²	45	68.4 Å²	68.4	24%	0.236	35%	0.35	C	S	.	.	H	α-helix	trans	-59.4	-52.3	173.8	177.9	67.8	0	0	0	111.3	L228 M230 L234 S235 M236 L307	L228-L232 WeakPolarHBondContact O-CB 3.46Å; L228-L232 PolarHBondContact O-N 3.21Å; M230-L232 VanDerWaalsContact C-N 3.35Å; L232-L234 VanDerWaalsContact C-N 3.31Å; L232-L234 PolarHBondContact O-N 3.1Å; L232-S235 PolarHBondContact O-N 3.3Å; L232-M236 VanDerWaalsContact O-CG 3.3Å; L232-M236 WeakPolarHBondContact O-CG 3.24Å; L232-M236 PolarHBondContact O-N 3.46Å; L232-L307 HydrophobicContact CD1-CB 4.44Å; L232-L307 HydrophobicContact CD1-CD1 3.87Å; L232-L307 HydrophobicContact CD1-CD2 3.65Å; L232-L307 HydrophobicContact CD1-CG 3.33Å; L232-L307 WeakPolarHBondContact CD1-O 3.48Å
233	L	81.2	Confident	75.5	Confident	97 Å²	97	64.9 Å²	64.9	51%	0.508	33%	0.332	S	S	.	.	H	α-helix	trans	-59.9	-43.8	177.9	-178.5	66.8	0	0	0	111.4	D229 M230 S235 M236 L237	D229-L233 WeakPolarHBondContact O-CB 3.5Å; D229-L233 PolarHBondContact O-N 2.84Å; M230-L233 PolarHBondContact O-N 3.13Å; L233-S235 VanDerWaalsContact C-N 3.32Å; L233-S235 PolarHBondContact O-N 3.28Å; L233-M236 WeakPolarHBondContact O-CB 3.39Å; L233-M236 PolarHBondContact O-N 3Å; L233-L237 HydrophobicContact CG-CD1 4.22Å; L233-L237 VanDerWaalsContact O-CG 3.27Å; L233-L237 WeakPolarHBondContact O-CG 3.49Å; L233-L237 PolarHBondContact O-N 3.49Å
234	L	83	Confident	77.9	Confident	47 Å²	47	58.1 Å²	58.1	25%	0.246	30%	0.301	C	S	.	.	H	α-helix	trans	-65.9	-34.6	-179.5	-173.8	48.3	0	0	0	112.2	I196 H197 P198 M230 E231 L232 M238	I196-L234 HydrophobicContact CB-CD1 4.16Å; I196-L234 HydrophobicContact CG2-CD1 3.26Å; H197-L234 WeakPolarHBondContact O-CD1 3.3Å; H197-L234 WeakPolarHBondContact O-CD2 3.45Å; H197-L234 VanDerWaalsContact O-CG 3.31Å; H197-L234 WeakPolarHBondContact O-CG 3.35Å; P198-L234 HydrophobicContact CB-CD2 4.5Å; P198-L234 HydrophobicContact CB-CG 4.38Å; M230-L234 WeakPolarHBondContact O-CB 3.34Å; M230-L234 PolarHBondContact O-N 2.85Å; E231-L234 PolarHBondContact O-N 2.72Å; L232-L234 VanDerWaalsContact C-N 3.31Å; L232-L234 PolarHBondContact O-N 3.1Å; L234-M238 PolarHBondContact O-N 2.86Å
235	S	83.1	Confident	79.7	Confident	7 Å²	7	54.7 Å²	54.7	5%	0.049	28%	0.284	C	S	.	.	H	α-helix	trans	-69	-43	172.1	-60.2	0	0	0	0	112.2	E231 L232 L233 L237 M238	E231-S235 WeakPolarHBondContact O-CB 3.28Å; E231-S235 PolarHBondContact O-N 3.13Å; E231-S235 PolarHBondContact O-OG 3.32Å; L232-S235 PolarHBondContact O-N 3.3Å; L233-S235 VanDerWaalsContact C-N 3.32Å; L233-S235 PolarHBondContact O-N 3.28Å; S235-L237 VanDerWaalsContact C-N 3.32Å; S235-L237 PolarHBondContact O-N 3.14Å; S235-M238 WeakPolarHBondContact O-CB 3.35Å; S235-M238 PolarHBondContact O-N 3.44Å
236	M	84.2	Confident	81.1	Confident	36 Å²	36	53.4 Å²	53.4	18%	0.177	28%	0.279	C	S	.	.	H	α-helix	trans	-60	-42.6	173.6	-66.3	-74.9	-64.4	0	0	111.4	L232 L233 M238 F239 M304 L307 V349	L232-M236 VanDerWaalsContact O-CG 3.3Å; L232-M236 WeakPolarHBondContact O-CG 3.24Å; L232-M236 PolarHBondContact O-N 3.46Å; L233-M236 WeakPolarHBondContact O-CB 3.39Å; L233-M236 PolarHBondContact O-N 3Å; M236-M238 PolarHBondContact O-N 3.19Å; M236-F239 PolarHBondContact O-N 3.41Å; M236-M304 HydrophobicContact CB-CE 4.34Å; M236-M304 HydrophobicContact CE-CB 3.84Å; M236-M304 HydrophobicContact CE-CE 3.95Å; M236-M304 HydrophobicContact CE-CG 3.89Å; M236-M304 HydrophobicContact CE-SD 3.66Å; M236-M304 VanDerWaalsContact O-CE 3.3Å; M236-M304 WeakPolarHBondContact O-CE 3.38Å; M236-M304 HydrophobicContact SD-CB 4.07Å; M236-M304 HydrophobicContact SD-CE 3.99Å; M236-M304 HydrophobicContact SD-CG 4.11Å; M236-M304 HydrophobicContact SD-SD 3.23Å; M236-L307 HydrophobicContact CG-CD2 3.96Å; M236-L307 HydrophobicContact SD-CD2 3.78Å; M236-V349 HydrophobicContact CE-CG2 4.49Å
237	L	87.8	Confident	82.5	Confident	58 Å²	58	53.1 Å²	53.1	30%	0.304	27%	0.267	S	S	.	.	H	α-helix	trans	-66.8	-19.8	180	-68.4	170.4	0	0	0	113.2	I196 L233 S235 F239 L240	I196-L237 HydrophobicContact CG2-CB 3.49Å; I196-L237 VanDerWaalsContact CG2-CB 3.49Å; I196-L237 HydrophobicContact CG2-CD1 3.94Å; I196-L237 HydrophobicContact CG2-CG 4.37Å; L233-L237 HydrophobicContact CG-CD1 4.22Å; L233-L237 VanDerWaalsContact O-CG 3.27Å; L233-L237 WeakPolarHBondContact O-CG 3.49Å; L233-L237 PolarHBondContact O-N 3.49Å; S235-L237 VanDerWaalsContact C-N 3.32Å; S235-L237 PolarHBondContact O-N 3.14Å; L237-F239 PolarHBondContact O-N 3.35Å; L237-L240 HydrophobicContact CB-CD1 4.3Å; L237-L240 HydrophobicContact CD2-CD1 3.58Å; L237-L240 HydrophobicContact CD2-CG 4.43Å; L237-L240 WeakPolarHBondContact O-CB 3.42Å; L237-L240 WeakPolarHBondContact O-CG 3.47Å; L237-L240 PolarHBondContact O-N 3.27Å
238	M	89.3	Confident	83.8	Confident	0 Å²	0	49.4 Å²	49.4	0%	0	25%	0.249	C	C	.	.	G	3₁₀ helix	trans	-65.7	-23.2	174.8	-73.5	-147.3	-68.2	0	0	113.8	M119 I196 H197 P198 L234 S235 M236 L240 R241	M119-M238 HydrophobicContact CB-CE 3.14Å; M119-M238 HydrophobicContact CG-CE 3.04Å; M119-M238 HydrophobicContact SD-CB 4.42Å; M119-M238 HydrophobicContact SD-CE 3.29Å; M119-M238 WeakPolarHBondContact SD-CE 3.44Å; I196-M238 WeakPolarHBondContact O-CG 3.07Å; H197-M238 HydrophobicContact CB-CG 4.37Å; H197-M238 HydrophobicContact CB-SD 3.49Å; H197-M238 WeakPolarHBondContact CB-SD 3.46Å; P198-M238 HydrophobicContact CG-CE 3.93Å; L234-M238 PolarHBondContact O-N 2.86Å; S235-M238 WeakPolarHBondContact O-CB 3.35Å; S235-M238 PolarHBondContact O-N 3.44Å; M236-M238 PolarHBondContact O-N 3.19Å; M238-L240 PolarHBondContact O-N 3.16Å; M238-R241 VanDerWaalsContact O-CB 3.24Å; M238-R241 WeakPolarHBondContact O-CB 3.14Å; M238-R241 WeakPolarHBondContact O-CD 3.49Å; M238-R241 WeakPolarHBondContact O-CG 3.42Å; M238-R241 PolarHBondContact O-N 2.86Å
239	F	89.6	Confident	84.9	Confident	20 Å²	20	48 Å²	48	9%	0.088	24%	0.241	C	C	.	.	G	3₁₀ helix	trans	-72.2	-14.8	173.2	-73.2	-102.1	0	0	0	112.9	I116 M119 I120 M236 L237 R241 L242 T300 W303 M304	I116-F239 HydrophobicContact CG2-CD1 4.5Å; I116-F239 HydrophobicContact CG2-CE1 3.93Å; I116-F239 HydrophobicContact CG2-CE2 4.3Å; I116-F239 HydrophobicContact CG2-CZ 3.82Å; M119-F239 HydrophobicContact CE-CE2 3.78Å; M119-F239 HydrophobicContact CE-CZ 4.14Å; M119-F239 HydrophobicContact SD-CE2 4.25Å; I120-F239 HydrophobicContact CD1-CZ 4.39Å; I120-F239 HydrophobicContact CG1-CZ 4.49Å; M236-F239 PolarHBondContact O-N 3.41Å; L237-F239 PolarHBondContact O-N 3.35Å; F239-R241 PolarHBondContact O-N 2.89Å; F239-R241 VanDerWaalsContact O-N 3.15Å; F239-L242 HydrophobicContact CB-CD1 4.38Å; F239-L242 HydrophobicContact CD1-CD1 3.89Å; F239-L242 VanDerWaalsContact O-CB 3.24Å; F239-L242 WeakPolarHBondContact O-CB 3.4Å; F239-L242 VanDerWaalsContact O-CG 3.3Å; F239-L242 WeakPolarHBondContact O-CG 3.25Å; F239-L242 PolarHBondContact O-N 3.27Å; F239-T300 HydrophobicContact CD1-CG2 4.14Å; F239-T300 HydrophobicContact CE1-CG2 4.13Å; F239-W303 HydrophobicContact CD2-CE3 4.41Å; F239-W303 HydrophobicContact CD2-CZ3 4.11Å; F239-W303 HydrophobicContact CE1-CE3 4.25Å; F239-W303 HydrophobicContact CE2-CD2 4.32Å; F239-W303 AromaticContact CE2-CE3 3.3Å; F239-W303 HydrophobicContact CE2-CE3 3.3Å; F239-W303 AromaticContact CE2-CH2 3.92Å; F239-W303 HydrophobicContact CE2-CH2 3.92Å; F239-W303 AromaticContact CE2-CZ3 3.07Å; F239-W303 HydrophobicContact CE2-CZ3 3.07Å; F239-W303 AromaticContact CZ-CD2 3.86Å; F239-W303 HydrophobicContact CZ-CD2 3.86Å; F239-W303 AromaticContact CZ-CE3 3.17Å; F239-W303 HydrophobicContact CZ-CE3 3.17Å; F239-W303 HydrophobicContact CZ-CH2 4.33Å; F239-W303 AromaticContact CZ-CZ3 3.49Å; F239-W303 HydrophobicContact CZ-CZ3 3.49Å; F239-W303 VanDerWaalsContact CZ-CZ3 3.49Å; F239-M304 HydrophobicContact CB-CE 3.32Å; F239-M304 HydrophobicContact CD1-CE 3.99Å; F239-M304 HydrophobicContact CD2-CE 3.11Å; F239-M304 HydrophobicContact CD2-SD 3.65Å; F239-M304 HydrophobicContact CE2-CE 3.89Å; F239-M304 HydrophobicContact CE2-SD 3.79Å; F239-M304 HydrophobicContact CG-CE 3.18Å; F239-M304 HydrophobicContact CG-SD 4.06Å; F239-M304 HydrophobicContact CZ-SD 4.29Å
240	L	88.4	Confident	85.5	Confident	87 Å²	87	46.9 Å²	46.9	46%	0.455	23%	0.234	S	C	.	.	G	3₁₀ helix	trans	-55.6	-31.8	170	-68.6	173.2	0	0	0	110.5	V193 L237 M238 L242 Y243	V193-L240 HydrophobicContact CG1-CB 3.66Å; V193-L240 HydrophobicContact CG1-CD1 4.39Å; L237-L240 HydrophobicContact CB-CD1 4.3Å; L237-L240 HydrophobicContact CD2-CD1 3.58Å; L237-L240 HydrophobicContact CD2-CG 4.43Å; L237-L240 WeakPolarHBondContact O-CB 3.42Å; L237-L240 WeakPolarHBondContact O-CG 3.47Å; L237-L240 PolarHBondContact O-N 3.27Å; M238-L240 PolarHBondContact O-N 3.16Å; L240-L242 PolarHBondContact O-N 3.09Å; L240-Y243 WeakPolarHBondContact O-CD1 3.19Å; L240-Y243 PolarHBondContact O-N 3.49Å
241	R	93.6	Very high	86	Confident	1 Å²	1	42.3 Å²	42.3	0%	0.004	21%	0.213	C	C	.	.	G	3₁₀ helix	trans	-56.6	-17.2	175.7	-59.6	175.8	-176.3	-173.6	2	114	A112 I116 T148 C194 I196 M238 F239 Y243 L244	A112-R241 HydrophobicContact CB-CB 4.43Å; I116-R241 HydrophobicContact CD1-CB 4.48Å; T148-R241 VanDerWaalsContact CG2-NH2 3.29Å; C194-R241 PolarHBondContact O-NH2 3.04Å; I196-R241 PolarHBondContact O-NH2 3.14Å; M238-R241 VanDerWaalsContact O-CB 3.24Å; M238-R241 WeakPolarHBondContact O-CB 3.14Å; M238-R241 WeakPolarHBondContact O-CD 3.49Å; M238-R241 WeakPolarHBondContact O-CG 3.42Å; M238-R241 PolarHBondContact O-N 2.86Å; F239-R241 PolarHBondContact O-N 2.89Å; F239-R241 VanDerWaalsContact O-N 3.15Å; R241-Y243 PolarHBondContact O-N 2.89Å; R241-Y243 VanDerWaalsContact O-N 3.1Å; R241-L244 WeakPolarHBondContact O-CB 3.36Å; R241-L244 WeakPolarHBondContact O-CG 3.16Å; R241-L244 PolarHBondContact O-N 3.49Å
242	L	90.1	Very high	86.4	Confident	55 Å²	55	44.3 Å²	44.3	29%	0.288	22%	0.222	S	C	.	.	G	3₁₀ helix	trans	-61.6	-12.5	171.4	-65.1	177.7	0	0	0	113.1	L113 I116 F239 L240 L244 V245 T300	L113-L242 HydrophobicContact CD2-CD2 4.16Å; I116-L242 HydrophobicContact CD1-CD2 3.95Å; I116-L242 HydrophobicContact CD1-CG 4.27Å; F239-L242 HydrophobicContact CB-CD1 4.38Å; F239-L242 HydrophobicContact CD1-CD1 3.89Å; F239-L242 VanDerWaalsContact O-CB 3.24Å; F239-L242 WeakPolarHBondContact O-CB 3.4Å; F239-L242 VanDerWaalsContact O-CG 3.3Å; F239-L242 WeakPolarHBondContact O-CG 3.25Å; F239-L242 PolarHBondContact O-N 3.27Å; L240-L242 PolarHBondContact O-N 3.09Å; L242-L244 PolarHBondContact O-N 3.06Å; L242-L244 VanDerWaalsContact O-N 3.13Å; L242-V245 HydrophobicContact CD2-CG2 4.19Å; L242-V245 VanDerWaalsContact O-CB 3.22Å; L242-V245 WeakPolarHBondContact O-CB 3.19Å; L242-V245 WeakPolarHBondContact O-CG2 3.4Å; L242-V245 PolarHBondContact O-N 3.31Å; L242-T300 HydrophobicContact CD1-CG2 3.81Å
243	Y	90.5	Very high	86.6	Confident	64 Å²	64	43.4 Å²	43.4	25%	0.251	22%	0.219	S	C	.	.	H	α-helix	trans	-56	-26.4	167.5	85.6	-97.6	0	0	0	112.3	E190 V193 C194 L240 R241 V245 H246 R247	E190-Y243 VanDerWaalsContact CD-OH 3.25Å; E190-Y243 HydrophobicContact CG-CE2 4.06Å; E190-Y243 WeakPolarHBondContact CG-OH 3.46Å; E190-Y243 WeakPolarHBondContact OE1-CE2 3.33Å; E190-Y243 PolarHBondContact OE1-OH 3.1Å; V193-Y243 HydrophobicContact CG1-CD1 4.3Å; V193-Y243 HydrophobicContact CG1-CE1 4.11Å; C194-Y243 PolarHBondContact SG-OH 2.93Å; L240-Y243 WeakPolarHBondContact O-CD1 3.19Å; L240-Y243 PolarHBondContact O-N 3.49Å; R241-Y243 PolarHBondContact O-N 2.89Å; R241-Y243 VanDerWaalsContact O-N 3.1Å; Y243-V245 PolarHBondContact O-N 3.34Å; Y243-H246 WeakPolarHBondContact O-CB 3.38Å; Y243-H246 PolarHBondContact O-N 3.37Å; Y243-H246 VanDerWaalsContact O-N 3.16Å; Y243-R247 PolarHBondContact O-N 3.47Å
244	L	90.9	Very high	86.1	Confident	3 Å²	3	47.7 Å²	47.7	2%	0.016	23%	0.234	C	C	.	.	H	α-helix	trans	-64.5	-28	175.6	-69.3	168.5	0	0	0	112.3	L109 A112 L151 R241 L242 H246 R247 A248	L109-L244 HydrophobicContact CD1-CB 4.22Å; A112-L244 HydrophobicContact CB-CD1 3.69Å; L151-L244 HydrophobicContact CD1-CD1 3.89Å; R241-L244 WeakPolarHBondContact O-CB 3.36Å; R241-L244 WeakPolarHBondContact O-CG 3.16Å; R241-L244 PolarHBondContact O-N 3.49Å; L242-L244 PolarHBondContact O-N 3.06Å; L242-L244 VanDerWaalsContact O-N 3.13Å; L244-H246 VanDerWaalsContact C-N 3.3Å; L244-H246 PolarHBondContact O-N 3.12Å; L244-R247 PolarHBondContact O-N 3.21Å; L244-A248 WeakPolarHBondContact O-CB 3.48Å; L244-A248 PolarHBondContact O-N 2.8Å
245	V	89.8	Confident	85.5	Confident	43 Å²	43	46.4 Å²	46.4	26%	0.261	23%	0.228	S	C	.	.	H	α-helix	trans	-60.1	-45.7	173.5	177.4	0	0	0	0	109.7	L109 L242 Y243 R247 A248 I249	L109-V245 HydrophobicContact CD1-CB 4.45Å; L109-V245 HydrophobicContact CD1-CG2 3.63Å; L242-V245 HydrophobicContact CD2-CG2 4.19Å; L242-V245 VanDerWaalsContact O-CB 3.22Å; L242-V245 WeakPolarHBondContact O-CB 3.19Å; L242-V245 WeakPolarHBondContact O-CG2 3.4Å; L242-V245 PolarHBondContact O-N 3.31Å; Y243-V245 PolarHBondContact O-N 3.34Å; V245-R247 VanDerWaalsContact C-N 3.34Å; V245-R247 PolarHBondContact O-N 2.91Å; V245-A248 PolarHBondContact O-N 3.35Å; V245-I249 HydrophobicContact CG1-CD1 3.83Å; V245-I249 HydrophobicContact CG1-CG1 4.39Å; V245-I249 VanDerWaalsContact O-CG1 3.29Å; V245-I249 WeakPolarHBondContact O-CG1 3.43Å; V245-I249 PolarHBondContact O-N 3.03Å
246	H	85.8	Confident	84.6	Confident	73 Å²	73	47 Å²	47	34%	0.338	23%	0.23	S	C	.	.	H	α-helix	trans	-58.6	-45.9	177.7	161.4	40.2	0	0	0	111.1	Y243 L244 I249 L250 F274	Y243-H246 WeakPolarHBondContact O-CB 3.38Å; Y243-H246 PolarHBondContact O-N 3.37Å; Y243-H246 VanDerWaalsContact O-N 3.16Å; L244-H246 VanDerWaalsContact C-N 3.3Å; L244-H246 PolarHBondContact O-N 3.12Å; H246-I249 PolarHBondContact O-N 2.97Å; H246-L250 PolarHBondContact O-N 2.87Å; H246-L250 VanDerWaalsContact O-N 3.14Å; H246-F274 WeakPolarHBondContact CE1-CB 3.26Å; H246-F274 AromaticContact CE1-CD1 3.36Å; H246-F274 WeakPolarHBondContact CE1-CD1 3.16Å; H246-F274 AromaticContact CE1-CD2 2.97Å; H246-F274 WeakPolarHBondContact CE1-CD2 3.29Å; H246-F274 AromaticContact CE1-CE1 3.88Å; H246-F274 AromaticContact CE1-CE2 3.55Å; H246-F274 AromaticContact CE1-CG 2.84Å; H246-F274 WeakPolarHBondContact CE1-CG 3.11Å; H246-F274 AromaticContact CE1-CZ 3.96Å; H246-F274 AromaticContact ND1-CD1 3.42Å; H246-F274 WeakPolarHBondContact ND1-CD1 3.38Å; H246-F274 AromaticContact ND1-CD2 2.98Å; H246-F274 WeakPolarHBondContact ND1-CD2 2.98Å; H246-F274 AromaticContact ND1-CE1 3.43Å; H246-F274 WeakPolarHBondContact ND1-CE1 2.97Å; H246-F274 AromaticContact ND1-CE2 2.99Å; H246-F274 WeakPolarHBondContact ND1-CE2 2.84Å; H246-F274 AromaticContact ND1-CG 3.19Å; H246-F274 WeakPolarHBondContact ND1-CG 3.4Å; H246-F274 AromaticContact ND1-CZ 3.22Å; H246-F274 WeakPolarHBondContact ND1-CZ 3.19Å; H246-F274 AromaticContact NE2-CG 3.79Å
247	R	87.6	Confident	83.8	Confident	48 Å²	48	48 Å²	48	18%	0.181	24%	0.236	C	C	.	.	H	α-helix	trans	-63.8	-41.6	175.6	-175.3	-178.9	-70	174.8	3.3	112.6	E190 Y243 L244 V245 L250 L251	E190-R247 IonicContact OE1-CZ 3.45Å; E190-R247 IonicContact OE1-NH1 3.91Å; E190-R247 PolarHBondContact OE1-NH1 3.36Å; E190-R247 IonicContact OE1-NH2 2.75Å; E190-R247 PolarHBondContact OE1-NH2 3.42Å; E190-R247 IonicContact OE2-CZ 3.41Å; E190-R247 IonicContact OE2-NH1 3.46Å; E190-R247 PolarHBondContact OE2-NH1 3.17Å; E190-R247 IonicContact OE2-NH2 2.81Å; E190-R247 PolarHBondContact OE2-NH2 2.97Å; Y243-R247 PolarHBondContact O-N 3.47Å; L244-R247 PolarHBondContact O-N 3.21Å; V245-R247 VanDerWaalsContact C-N 3.34Å; V245-R247 PolarHBondContact O-N 2.91Å; R247-L250 WeakPolarHBondContact O-CB 3.39Å; R247-L250 PolarHBondContact O-N 3.27Å; R247-L251 PolarHBondContact O-N 3.43Å
248	A	87.6	Confident	83.2	Confident	8 Å²	8	47.1 Å²	47.1	7%	0.066	24%	0.235	C	C	.	.	H	α-helix	trans	-64	-43.1	179	0	0	0	0	0	111.6	L109 L244 V245 L250 L251 H252	L109-A248 HydrophobicContact CD2-CB 3.67Å; L244-A248 WeakPolarHBondContact O-CB 3.48Å; L244-A248 PolarHBondContact O-N 2.8Å; V245-A248 PolarHBondContact O-N 3.35Å; A248-L250 VanDerWaalsContact C-N 3.3Å; A248-L250 PolarHBondContact O-N 3.44Å; A248-L251 PolarHBondContact O-N 3.08Å; A248-H252 VanDerWaalsContact O-CB 3.29Å; A248-H252 WeakPolarHBondContact O-CB 3.36Å; A248-H252 PolarHBondContact O-CD2 3.43Å; A248-H252 PolarHBondContact O-N 3.34Å
249	I	85.9	Confident	82.4	Confident	71 Å²	71	50.9 Å²	50.9	36%	0.364	27%	0.266	S	S	.	.	H	α-helix	trans	-58.2	-44.7	174.4	-68.9	165.7	0	0	0	110.6	V245 H246 S253 L281	V245-I249 HydrophobicContact CG1-CD1 3.83Å; V245-I249 HydrophobicContact CG1-CG1 4.39Å; V245-I249 VanDerWaalsContact O-CG1 3.29Å; V245-I249 WeakPolarHBondContact O-CG1 3.43Å; V245-I249 PolarHBondContact O-N 3.03Å; H246-I249 PolarHBondContact O-N 2.97Å; I249-S253 WeakPolarHBondContact O-CB 3.39Å; I249-S253 PolarHBondContact O-N 3.47Å; I249-S253 VanDerWaalsContact O-N 3.17Å; I249-L281 HydrophobicContact CG2-CD2 4.5Å
250	L	83.6	Confident	81.9	Confident	46 Å²	46	53.5 Å²	53.5	24%	0.241	29%	0.287	C	S	.	.	H	α-helix	trans	-58.8	-53	178	-171.7	76.9	0	0	0	110.4	H246 R247 A248 S253 L256 F274 V277	H246-L250 PolarHBondContact O-N 2.87Å; H246-L250 VanDerWaalsContact O-N 3.14Å; R247-L250 WeakPolarHBondContact O-CB 3.39Å; R247-L250 PolarHBondContact O-N 3.27Å; A248-L250 VanDerWaalsContact C-N 3.3Å; A248-L250 PolarHBondContact O-N 3.44Å; L250-S253 WeakPolarHBondContact O-CB 3.44Å; L250-S253 PolarHBondContact O-N 2.96Å; L250-L256 HydrophobicContact CB-CD1 4.35Å; L250-L256 HydrophobicContact CD1-CD1 3.36Å; L250-L256 HydrophobicContact CD2-CD1 4.44Å; L250-L256 HydrophobicContact CG-CD1 3.39Å; L250-L256 WeakPolarHBondContact O-CD1 3.47Å; L250-F274 HydrophobicContact CD1-CB 4.16Å; L250-V277 HydrophobicContact CD1-CB 4.38Å; L250-V277 HydrophobicContact CD1-CG2 3.91Å
251	L	82.4	Confident	81.5	Confident	32 Å²	32	55 Å²	55	17%	0.168	29%	0.287	C	S	.	.	H	α-helix	trans	-77.9	-28.3	-171.3	-163.8	60.3	0	0	0	114.1	K101 K102 C105 F158 R247 A248 S253	K101-L251 HydrophobicContact CB-CD2 4.21Å; K101-L251 WeakPolarHBondContact O-CD2 3.34Å; K102-L251 HydrophobicContact CB-CD2 4.32Å; K102-L251 HydrophobicContact CB-CG 4.19Å; C105-L251 HydrophobicContact CB-CD2 3.73Å; F158-L251 HydrophobicContact CE2-CD2 3.91Å; R247-L251 PolarHBondContact O-N 3.43Å; A248-L251 PolarHBondContact O-N 3.08Å; L251-S253 VanDerWaalsContact C-N 3.34Å
252	H	82.8	Confident	80.8	Confident	90 Å²	90	58.4 Å²	58.4	42%	0.417	30%	0.3	S	S	.	.	H	α-helix	trans	-82	-12	173.5	-84.2	-101.4	0	0	0	113.5	A248 K254	A248-H252 VanDerWaalsContact O-CB 3.29Å; A248-H252 WeakPolarHBondContact O-CB 3.36Å; A248-H252 PolarHBondContact O-CD2 3.43Å; A248-H252 PolarHBondContact O-N 3.34Å; H252-K254 PolarHBondContact O-N 3.2Å
253	S	80.5	Confident	80.3	Confident	26 Å²	26	58.8 Å²	58.8	18%	0.182	31%	0.307	C	S	.	.			trans	-66	117.2	175.9	-176.2	0	0	0	0	110.5	I249 L250 L251 V255 L256	I249-S253 WeakPolarHBondContact O-CB 3.39Å; I249-S253 PolarHBondContact O-N 3.47Å; I249-S253 VanDerWaalsContact O-N 3.17Å; L250-S253 WeakPolarHBondContact O-CB 3.44Å; L250-S253 PolarHBondContact O-N 2.96Å; L251-S253 VanDerWaalsContact C-N 3.34Å; S253-V255 PolarHBondContact O-N 2.88Å; S253-V255 WeakPolarHBondContact OG-CB 3.21Å; S253-L256 PolarHBondContact O-N 3.3Å
254	K	72.2	Confident	80.1	Confident	187 Å²	187	60.6 Å²	60.6	81%	0.813	32%	0.32	S	S	*	.	H	α-helix	trans	-54.4	-25	175	-67.4	-176.9	177.6	-177.8	0	112.7	H252 L256 L257 S258	H252-K254 PolarHBondContact O-N 3.2Å; K254-L256 VanDerWaalsContact C-N 3.32Å; K254-L256 PolarHBondContact O-N 2.72Å; K254-L257 PolarHBondContact O-N 2.84Å; K254-S258 PolarHBondContact O-N 2.96Å
255	V	69.4	Low	79.7	Confident	20 Å²	20	60.7 Å²	60.7	12%	0.121	32%	0.322	C	S	.	.	H	α-helix	trans	-63	-35.5	178.7	178.6	0	0	0	0	111.9	S253 Y261 F276 V280	S253-V255 PolarHBondContact O-N 2.88Å; S253-V255 WeakPolarHBondContact OG-CB 3.21Å; V255-Y261 HydrophobicContact CG1-CD1 3.68Å; V255-Y261 HydrophobicContact CG1-CE1 3.81Å; V255-Y261 HydrophobicContact CG1-CG 4.37Å; V255-Y261 WeakPolarHBondContact O-CB 3.48Å; V255-F276 HydrophobicContact CG1-CE1 4.07Å; V255-V280 HydrophobicContact CG2-CG1 4.28Å
256	L	63.9	Low	79.4	Confident	20 Å²	20	62.4 Å²	62.4	11%	0.105	34%	0.336	C	S	.	.	H	α-helix	trans	-87.1	-22.7	-178.2	-62.2	-166.9	0	0	0	114.2	L250 S253 K254 R262 F272 V277	L250-L256 HydrophobicContact CB-CD1 4.35Å; L250-L256 HydrophobicContact CD1-CD1 3.36Å; L250-L256 HydrophobicContact CD2-CD1 4.44Å; L250-L256 HydrophobicContact CG-CD1 3.39Å; L250-L256 WeakPolarHBondContact O-CD1 3.47Å; S253-L256 PolarHBondContact O-N 3.3Å; K254-L256 VanDerWaalsContact C-N 3.32Å; K254-L256 PolarHBondContact O-N 2.72Å; L256-R262 PolarHBondContact O-NE 2.61Å; L256-R262 PolarHBondContact O-NH2 3.46Å; L256-F272 HydrophobicContact CD2-CB 3.56Å; L256-F272 HydrophobicContact CD2-CD1 3.76Å; L256-F272 HydrophobicContact CD2-CG 3.92Å; L256-V277 HydrophobicContact CD1-CG2 3.87Å; L256-V277 HydrophobicContact CD2-CG2 3.59Å; L256-V277 HydrophobicContact CG-CG2 3.74Å
257	L	68.4	Low	79.5	Confident	55 Å²	55	65.2 Å²	65.2	29%	0.288	35%	0.352	S	S	.	.	H	α-helix	trans	-88.5	-26.8	-175.7	-126.1	81.6	0	0	0	112.6	I98 K254 A259	I98-L257 HydrophobicContact CG2-CD1 3.38Å; I98-L257 HydrophobicContact CG2-CD2 4.12Å; I98-L257 HydrophobicContact CG2-CG 3.7Å; K254-L257 PolarHBondContact O-N 2.84Å; L257-A259 PolarHBondContact O-N 3.31Å
258	S	75.1	Confident	79.5	Confident	41 Å²	41	67.8 Å²	67.8	29%	0.287	37%	0.37	S	S	.	.			trans	-70.2	128	-175.8	176.2	0	0	0	0	111.6	K254 S260 Y261 R262	K254-S258 PolarHBondContact O-N 2.96Å; S258-S260 PolarHBondContact O-N 3.45Å; S258-Y261 PolarHBondContact O-N 3.12Å; S258-R262 PolarHBondContact O-N 3.45Å; S258-R262 VanDerWaalsContact O-N 3.15Å
259	A	71.7	Confident	79.3	Confident	78 Å²	78	74.4 Å²	74.4	65%	0.645	40%	0.404	S	S	*	.	H	α-helix	trans	-58.5	-36.6	176.9	0	0	0	0	0	112.2	L257 Y261 R262 S263	L257-A259 PolarHBondContact O-N 3.31Å; A259-Y261 PolarHBondContact O-N 2.96Å; A259-R262 PolarHBondContact O-N 3.46Å; A259-S263 WeakPolarHBondContact O-CB 3.2Å; A259-S263 PolarHBondContact O-N 3.35Å
260	S	79.1	Confident	79.1	Confident	76 Å²	76	74.7 Å²	74.7	53%	0.531	41%	0.406	S	S	.	.	H	α-helix	trans	-62.4	-43.2	177.5	-48.1	0	0	0	0	111.8	S258 S263 I264	S258-S260 PolarHBondContact O-N 3.45Å; S260-S263 PolarHBondContact O-N 3.34Å; S260-I264 VanDerWaalsContact O-CG1 3.28Å; S260-I264 WeakPolarHBondContact O-CG1 3.45Å; S260-I264 PolarHBondContact O-N 3.26Å
261	Y	79.8	Confident	78.8	Confident	119 Å²	119	79 Å²	79	47%	0.467	43%	0.429	S	S	.	.	H	α-helix	trans	-63.8	-46	175.7	-81	-97.1	0	0	0	110.5	V255 S258 A259 S263 I264 G265 F272	V255-Y261 HydrophobicContact CG1-CD1 3.68Å; V255-Y261 HydrophobicContact CG1-CE1 3.81Å; V255-Y261 HydrophobicContact CG1-CG 4.37Å; V255-Y261 WeakPolarHBondContact O-CB 3.48Å; S258-Y261 PolarHBondContact O-N 3.12Å; A259-Y261 PolarHBondContact O-N 2.96Å; Y261-S263 VanDerWaalsContact C-N 3.34Å; Y261-S263 PolarHBondContact O-N 2.81Å; Y261-I264 PolarHBondContact O-N 3.47Å; Y261-G265 PolarHBondContact O-N 2.93Å; Y261-F272 WeakPolarHBondContact O-CZ 3.45Å
262	R	78.8	Confident	78.5	Confident	71 Å²	71	80.4 Å²	80.4	27%	0.268	43%	0.434	S	S	.	.	H	α-helix	trans	-60.1	-42	178.8	-69	-176.9	-172.8	173.8	1.5	113.2	I98 L256 S258 A259 G265 S266 F272	I98-R262 VanDerWaalsContact CD1-NH1 3.33Å; L256-R262 PolarHBondContact O-NE 2.61Å; L256-R262 PolarHBondContact O-NH2 3.46Å; S258-R262 PolarHBondContact O-N 3.45Å; S258-R262 VanDerWaalsContact O-N 3.15Å; A259-R262 PolarHBondContact O-N 3.46Å; R262-G265 PolarHBondContact O-N 3.06Å; R262-S266 PolarHBondContact O-N 3.39Å; R262-S266 PolarHBondContact O-OG 3.22Å; R262-F272 HydrophobicContact CG-CE2 4.42Å
263	S	81.4	Confident	78.4	Confident	64 Å²	64	79.7 Å²	79.7	45%	0.448	44%	0.436	S	S	.	.	H	α-helix	trans	-64.4	-48.9	177.1	179.2	0	0	0	0	112	A259 S260 Y261 G265 S266 L267	A259-S263 WeakPolarHBondContact O-CB 3.2Å; A259-S263 PolarHBondContact O-N 3.35Å; S260-S263 PolarHBondContact O-N 3.34Å; Y261-S263 VanDerWaalsContact C-N 3.34Å; Y261-S263 PolarHBondContact O-N 2.81Å; S263-G265 VanDerWaalsContact C-N 3.26Å; S263-G265 PolarHBondContact O-N 3.01Å; S263-S266 PolarHBondContact O-N 3.03Å; S263-S266 PolarHBondContact O-OG 3.42Å; S263-L267 WeakPolarHBondContact O-CG 3.38Å; S263-L267 PolarHBondContact O-N 3.35Å
264	I	85.3	Confident	78.4	Confident	102 Å²	102	81.6 Å²	81.6	52%	0.523	44%	0.441	S	S	.	.	H	α-helix	trans	-63.6	-35.6	176.4	-64.3	166.6	0	0	0	110.9	S260 Y261 L267 N268	S260-I264 VanDerWaalsContact O-CG1 3.28Å; S260-I264 WeakPolarHBondContact O-CG1 3.45Å; S260-I264 PolarHBondContact O-N 3.26Å; Y261-I264 PolarHBondContact O-N 3.47Å; I264-L267 PolarHBondContact O-N 2.89Å; I264-N268 PolarHBondContact O-N 3.34Å; I264-N268 VanDerWaalsContact O-N 3.13Å; I264-N268 PolarHBondContact O-ND2 3.38Å
265	G	82.9	Confident	78.9	Confident	5 Å²	5	81.3 Å²	81.3	5%	0.052	44%	0.435	C	S	.	.	H	α-helix	trans	-66.2	-44.3	176.3	0	0	0	0	0	113	Y261 R262 S263 N268 N269 I270	Y261-G265 PolarHBondContact O-N 2.93Å; R262-G265 PolarHBondContact O-N 3.06Å; S263-G265 VanDerWaalsContact C-N 3.26Å; S263-G265 PolarHBondContact O-N 3.01Å; G265-N268 CarbonylContact O-C 3.55Å; G265-N268 PolarHBondContact O-N 3.18Å; G265-N269 PolarHBondContact O-N 2.92Å; G265-I270 PolarHBondContact O-N 3.29Å
266	S	83.7	Confident	79.7	Confident	78 Å²	78	83.4 Å²	83.4	55%	0.545	44%	0.442	S	S	.	.	H	α-helix	trans	-65.9	-38.6	175.3	56.9	0	0	0	0	111.8	R262 S263 N268 N269	R262-S266 PolarHBondContact O-N 3.39Å; R262-S266 PolarHBondContact O-OG 3.22Å; S263-S266 PolarHBondContact O-N 3.03Å; S263-S266 PolarHBondContact O-OG 3.42Å; S266-N268 PolarHBondContact O-N 2.86Å; S266-N269 PolarHBondContact O-N 2.87Å; S266-N269 VanDerWaalsContact O-N 3.13Å
267	L	87.8	Confident	80.7	Confident	132 Å²	132	82.6 Å²	82.6	69%	0.691	44%	0.438	S	S	*	.	H	α-helix	trans	-61.1	-33.8	175.4	-72.7	172.4	0	0	0	112.6	S263 I264	S263-L267 WeakPolarHBondContact O-CG 3.38Å; S263-L267 PolarHBondContact O-N 3.35Å; I264-L267 PolarHBondContact O-N 2.89Å
268	N	86.4	Confident	81.4	Confident	103 Å²	103	83.3 Å²	83.3	55%	0.551	44%	0.442	S	S	*	.	T	Hydrogen-bonded Turn	trans	-96.6	7.1	177.9	-68.8	-71.7	0	0	0	113.6	I264 G265 S266 I270	I264-N268 PolarHBondContact O-N 3.34Å; I264-N268 VanDerWaalsContact O-N 3.13Å; I264-N268 PolarHBondContact O-ND2 3.38Å; G265-N268 CarbonylContact O-C 3.55Å; G265-N268 PolarHBondContact O-N 3.18Å; S266-N268 PolarHBondContact O-N 2.86Å; N268-I270 HydrophobicContact CB-CD1 3.8Å; N268-I270 HydrophobicContact CB-CG1 3.87Å; N268-I270 PolarHBondContact O-N 3.47Å
269	N	84.8	Confident	82	Confident	147 Å²	147	87.4 Å²	87.4	79%	0.786	46%	0.455	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.2	36	-174.6	-65.2	-57	0	0	0	114.2	G265 S266	G265-N269 PolarHBondContact O-N 2.92Å; S266-N269 PolarHBondContact O-N 2.87Å; S266-N269 VanDerWaalsContact O-N 3.13Å
270	I	81.8	Confident	82.8	Confident	76 Å²	76	86 Å²	86	39%	0.39	44%	0.438	S	S	.	.			trans	-94.6	117.5	179.5	-58.5	174.6	0	0	0	109.6	G265 N268 F272	G265-I270 PolarHBondContact O-N 3.29Å; N268-I270 HydrophobicContact CB-CD1 3.8Å; N268-I270 HydrophobicContact CB-CG1 3.87Å; N268-I270 PolarHBondContact O-N 3.47Å; I270-F272 PolarHBondContact O-N 2.92Å
271	N	75.8	Confident	83.1	Confident	138 Å²	138	85.1 Å²	85.1	74%	0.738	43%	0.427	S	S	*	.			trans	-77.4	122.2	170.3	-72.1	-33.2	0	0	0	110.7	T273	N271-T273 VanDerWaalsContact C-N 3.33Å; N271-T273 HydrophobicContact CB-CG2 4.44Å; N271-T273 PolarHBondContact O-N 3.27Å
272	F	76.5	Confident	83.4	Confident	61 Å²	61	81 Å²	81	27%	0.268	41%	0.412	S	S	.	.			trans	-71.5	84.2	177.8	-67.7	-74.8	0	0	0	112	L256 Y261 R262 I270 F276	L256-F272 HydrophobicContact CD2-CB 3.56Å; L256-F272 HydrophobicContact CD2-CD1 3.76Å; L256-F272 HydrophobicContact CD2-CG 3.92Å; Y261-F272 WeakPolarHBondContact O-CZ 3.45Å; R262-F272 HydrophobicContact CG-CE2 4.42Å; I270-F272 PolarHBondContact O-N 2.92Å; F272-F276 HydrophobicContact CD1-CD1 4.16Å; F272-F276 HydrophobicContact CD1-CE1 4.13Å; F272-F276 HydrophobicContact CE1-CE1 4.18Å
273	T	81.6	Confident	83.8	Confident	74 Å²	74	82.1 Å²	82.1	45%	0.454	42%	0.424	S	S	.	.			trans	-93.8	165.7	177.3	59.7	0	0	0	0	111.8	N271 R275 F276 V277	N271-T273 VanDerWaalsContact C-N 3.33Å; N271-T273 HydrophobicContact CB-CG2 4.44Å; N271-T273 PolarHBondContact O-N 3.27Å; T273-R275 VanDerWaalsContact C-N 3.27Å; T273-R275 PolarHBondContact O-N 3.27Å; T273-F276 WeakPolarHBondContact O-CB 3.1Å; T273-F276 PolarHBondContact O-N 3.49Å; T273-F276 VanDerWaalsContact O-N 3.16Å; T273-V277 PolarHBondContact O-N 3.21Å
274	F	79.4	Confident	84.2	Confident	67 Å²	67	86.1 Å²	86.1	29%	0.294	43%	0.433	S	S	.	.	H	α-helix	trans	-55.3	-42.6	171.2	175.6	-127.5	0	0	0	113.6	H246 L250 F276 V277 L278	H246-F274 WeakPolarHBondContact CE1-CB 3.26Å; H246-F274 AromaticContact CE1-CD1 3.36Å; H246-F274 WeakPolarHBondContact CE1-CD1 3.16Å; H246-F274 AromaticContact CE1-CD2 2.97Å; H246-F274 WeakPolarHBondContact CE1-CD2 3.29Å; H246-F274 AromaticContact CE1-CE1 3.88Å; H246-F274 AromaticContact CE1-CE2 3.55Å; H246-F274 AromaticContact CE1-CG 2.84Å; H246-F274 WeakPolarHBondContact CE1-CG 3.11Å; H246-F274 AromaticContact CE1-CZ 3.96Å; H246-F274 AromaticContact ND1-CD1 3.42Å; H246-F274 WeakPolarHBondContact ND1-CD1 3.38Å; H246-F274 AromaticContact ND1-CD2 2.98Å; H246-F274 WeakPolarHBondContact ND1-CD2 2.98Å; H246-F274 AromaticContact ND1-CE1 3.43Å; H246-F274 WeakPolarHBondContact ND1-CE1 2.97Å; H246-F274 AromaticContact ND1-CE2 2.99Å; H246-F274 WeakPolarHBondContact ND1-CE2 2.84Å; H246-F274 AromaticContact ND1-CG 3.19Å; H246-F274 WeakPolarHBondContact ND1-CG 3.4Å; H246-F274 AromaticContact ND1-CZ 3.22Å; H246-F274 WeakPolarHBondContact ND1-CZ 3.19Å; H246-F274 AromaticContact NE2-CG 3.79Å; L250-F274 HydrophobicContact CD1-CB 4.16Å; F274-F276 PolarHBondContact O-N 3.2Å; F274-V277 PolarHBondContact O-N 3.43Å; F274-L278 HydrophobicContact CE1-CB 4.45Å; F274-L278 HydrophobicContact CE1-CD2 4.02Å; F274-L278 HydrophobicContact CE2-CB 4.15Å; F274-L278 HydrophobicContact CZ-CB 4.12Å; F274-L278 HydrophobicContact CZ-CD1 4.33Å; F274-L278 HydrophobicContact CZ-CD2 4.04Å; F274-L278 HydrophobicContact CZ-CG 4.4Å; F274-L278 WeakPolarHBondContact O-CB 3.33Å; F274-L278 PolarHBondContact O-N 2.88Å
275	R	84.5	Confident	84.3	Confident	180 Å²	180	85.1 Å²	85.1	68%	0.679	43%	0.426	S	S	*	.	H	α-helix	trans	-57.3	-36.1	-179.2	-173.9	176.3	-178.3	179.9	-1	111	T273 K279	T273-R275 VanDerWaalsContact C-N 3.27Å; T273-R275 PolarHBondContact O-N 3.27Å; R275-K279 WeakPolarHBondContact O-CB 3.36Å; R275-K279 WeakPolarHBondContact O-CG 3.35Å; R275-K279 PolarHBondContact O-N 3.15Å; R275-K279 VanDerWaalsContact O-N 3.09Å
276	F	85.4	Confident	84.7	Confident	64 Å²	64	85.6 Å²	85.6	28%	0.281	43%	0.428	S	S	.	.	H	α-helix	trans	-66.5	-48.8	173.8	179.2	-100	0	0	0	111.7	V255 F272 T273 F274 L278 K279 V280	V255-F276 HydrophobicContact CG1-CE1 4.07Å; F272-F276 HydrophobicContact CD1-CD1 4.16Å; F272-F276 HydrophobicContact CD1-CE1 4.13Å; F272-F276 HydrophobicContact CE1-CE1 4.18Å; T273-F276 WeakPolarHBondContact O-CB 3.1Å; T273-F276 PolarHBondContact O-N 3.49Å; T273-F276 VanDerWaalsContact O-N 3.16Å; F274-F276 PolarHBondContact O-N 3.2Å; F276-L278 PolarHBondContact O-N 2.91Å; F276-K279 WeakPolarHBondContact O-CB 3.47Å; F276-K279 PolarHBondContact O-N 3.4Å; F276-V280 HydrophobicContact CD1-CG2 4.21Å; F276-V280 HydrophobicContact CE1-CG2 3.81Å; F276-V280 HydrophobicContact CE2-CG2 4.22Å; F276-V280 HydrophobicContact CZ-CG2 3.81Å; F276-V280 WeakPolarHBondContact O-CG2 3.46Å; F276-V280 PolarHBondContact O-N 2.93Å
277	V	85	Confident	85	Confident	4 Å²	4	85.4 Å²	85.4	2%	0.024	43%	0.431	C	S	.	.	H	α-helix	trans	-62.2	-42.2	179.4	177.3	0	0	0	0	112.1	L250 L256 T273 F274 V280 L281	L250-V277 HydrophobicContact CD1-CB 4.38Å; L250-V277 HydrophobicContact CD1-CG2 3.91Å; L256-V277 HydrophobicContact CD1-CG2 3.87Å; L256-V277 HydrophobicContact CD2-CG2 3.59Å; L256-V277 HydrophobicContact CG-CG2 3.74Å; T273-V277 PolarHBondContact O-N 3.21Å; F274-V277 PolarHBondContact O-N 3.43Å; V277-V280 PolarHBondContact O-N 3.48Å; V277-L281 WeakPolarHBondContact O-CB 3.44Å; V277-L281 PolarHBondContact O-N 3.33Å
278	L	83.4	Confident	85.1	Confident	69 Å²	69	87.9 Å²	87.9	36%	0.361	43%	0.432	S	S	.	.	H	α-helix	trans	-61.7	-44.3	176	-176.3	62.6	0	0	0	111	F274 F276 V280 L281 M282	F274-L278 HydrophobicContact CE1-CB 4.45Å; F274-L278 HydrophobicContact CE1-CD2 4.02Å; F274-L278 HydrophobicContact CE2-CB 4.15Å; F274-L278 HydrophobicContact CZ-CB 4.12Å; F274-L278 HydrophobicContact CZ-CD1 4.33Å; F274-L278 HydrophobicContact CZ-CD2 4.04Å; F274-L278 HydrophobicContact CZ-CG 4.4Å; F274-L278 WeakPolarHBondContact O-CB 3.33Å; F274-L278 PolarHBondContact O-N 2.88Å; F276-L278 PolarHBondContact O-N 2.91Å; L278-V280 PolarHBondContact O-N 3.22Å; L278-L281 PolarHBondContact O-N 3.19Å; L278-M282 HydrophobicContact CD1-CE 4.04Å; L278-M282 HydrophobicContact CD1-CG 4.32Å; L278-M282 HydrophobicContact CG-CG 4.44Å; L278-M282 WeakPolarHBondContact O-CB 3.31Å; L278-M282 VanDerWaalsContact O-CG 3.25Å; L278-M282 WeakPolarHBondContact O-CG 3.41Å; L278-M282 PolarHBondContact O-N 3.49Å
279	K	87.4	Confident	85.3	Confident	127 Å²	127	84 Å²	84	55%	0.552	41%	0.412	S	S	*	.	H	α-helix	trans	-59.1	-44.9	173.8	-77.1	174.3	177.5	-171.9	0	112.2	R275 F276 L281 M282 N283	R275-K279 WeakPolarHBondContact O-CB 3.36Å; R275-K279 WeakPolarHBondContact O-CG 3.35Å; R275-K279 PolarHBondContact O-N 3.15Å; R275-K279 VanDerWaalsContact O-N 3.09Å; F276-K279 WeakPolarHBondContact O-CB 3.47Å; F276-K279 PolarHBondContact O-N 3.4Å; K279-L281 VanDerWaalsContact C-N 3.34Å; K279-L281 PolarHBondContact O-N 3.45Å; K279-M282 PolarHBondContact O-N 3.17Å; K279-N283 WeakPolarHBondContact O-CB 3.05Å; K279-N283 PolarHBondContact O-N 3.49Å
280	V	87.4	Confident	85.7	Confident	48 Å²	48	77.7 Å²	77.7	29%	0.291	38%	0.378	S	S	.	.	H	α-helix	trans	-62.9	-42.5	177.8	172.5	0	0	0	0	111	V255 F276 V277 L278 N283 K284	V255-V280 HydrophobicContact CG2-CG1 4.28Å; F276-V280 HydrophobicContact CD1-CG2 4.21Å; F276-V280 HydrophobicContact CE1-CG2 3.81Å; F276-V280 HydrophobicContact CE2-CG2 4.22Å; F276-V280 HydrophobicContact CZ-CG2 3.81Å; F276-V280 WeakPolarHBondContact O-CG2 3.46Å; F276-V280 PolarHBondContact O-N 2.93Å; V277-V280 PolarHBondContact O-N 3.48Å; L278-V280 PolarHBondContact O-N 3.22Å; V280-N283 PolarHBondContact O-N 3.45Å; V280-K284 VanDerWaalsContact O-CB 3.29Å; V280-K284 WeakPolarHBondContact O-CB 3.22Å; V280-K284 PolarHBondContact O-N 3.01Å
281	L	85.9	Confident	86.2	Confident	59 Å²	59	78.9 Å²	78.9	31%	0.309	38%	0.384	S	S	.	.	H	α-helix	trans	-66.4	-44.9	179.6	-176.8	58.9	0	0	0	111.7	I249 V277 L278 K279 N283 K284 H285 T289	I249-L281 HydrophobicContact CG2-CD2 4.5Å; V277-L281 WeakPolarHBondContact O-CB 3.44Å; V277-L281 PolarHBondContact O-N 3.33Å; L278-L281 PolarHBondContact O-N 3.19Å; K279-L281 VanDerWaalsContact C-N 3.34Å; K279-L281 PolarHBondContact O-N 3.45Å; L281-N283 VanDerWaalsContact C-N 3.34Å; L281-N283 PolarHBondContact O-N 2.84Å; L281-K284 PolarHBondContact O-N 3.49Å; L281-H285 PolarHBondContact O-N 2.94Å; L281-T289 HydrophobicContact CD1-CG2 3.43Å; L281-T289 VanDerWaalsContact CD1-CG2 3.43Å; L281-T289 HydrophobicContact CD2-CG2 3.94Å; L281-T289 HydrophobicContact CG-CG2 3.38Å
282	M	86.6	Confident	87	Confident	31 Å²	31	76.2 Å²	76.2	15%	0.153	37%	0.373	C	S	.	.	H	α-helix	trans	-62.8	-37.7	174.9	-71.8	-63.3	120.6	0	0	112.1	L278 K279 P286 T289 M363	L278-M282 HydrophobicContact CD1-CE 4.04Å; L278-M282 HydrophobicContact CD1-CG 4.32Å; L278-M282 HydrophobicContact CG-CG 4.44Å; L278-M282 WeakPolarHBondContact O-CB 3.31Å; L278-M282 VanDerWaalsContact O-CG 3.25Å; L278-M282 WeakPolarHBondContact O-CG 3.41Å; L278-M282 PolarHBondContact O-N 3.49Å; K279-M282 PolarHBondContact O-N 3.17Å; M282-P286 WeakPolarHBondContact O-CA 2.99Å; M282-P286 WeakPolarHBondContact O-CB 3.43Å; M282-P286 VanDerWaalsContact O-CD 3.26Å; M282-P286 WeakPolarHBondContact O-CD 2.98Å; M282-T289 HydrophobicContact CE-CG2 4.4Å; M282-T289 WeakPolarHBondContact CE-OG1 3.37Å; M282-M363 HydrophobicContact SD-CE 4.08Å; M282-M363 HydrophobicContact SD-SD 4.04Å
283	N	87.3	Confident	87.7	Confident	96 Å²	96	77.6 Å²	77.6	51%	0.513	38%	0.379	S	S	.	.	H	α-helix	trans	-74.7	-39.5	179	-167.2	21.5	0	0	0	112.4	K279 V280 L281	K279-N283 WeakPolarHBondContact O-CB 3.05Å; K279-N283 PolarHBondContact O-N 3.49Å; V280-N283 PolarHBondContact O-N 3.45Å; L281-N283 VanDerWaalsContact C-N 3.34Å; L281-N283 PolarHBondContact O-N 2.84Å
284	K	88.9	Confident	88.4	Confident	147 Å²	147	75.6 Å²	75.6	64%	0.639	37%	0.365	S	S	*	.	H	α-helix	trans	-72.8	-49.4	-177.2	-168.4	177.3	-179.8	170.3	0	112.5	V280 L281	V280-K284 VanDerWaalsContact O-CB 3.29Å; V280-K284 WeakPolarHBondContact O-CB 3.22Å; V280-K284 PolarHBondContact O-N 3.01Å; L281-K284 PolarHBondContact O-N 3.49Å
285	H	89.1	Confident	89.1	Confident	81 Å²	81	76.6 Å²	76.6	38%	0.375	37%	0.373	S	S	.	.	S	Bend	trans	-135.7	65.9	-176.7	-58.5	-41.3	0	0	0	111.4	L281 A287 R288 T289	L281-H285 PolarHBondContact O-N 2.94Å; H285-A287 PolarHBondContact O-N 3.03Å; H285-R288 HydrophobicContact CB-CB 4.47Å; H285-T289 HydrophobicContact CB-CG2 4.28Å; H285-T289 WeakPolarHBondContact O-CB 3.47Å; H285-T289 WeakPolarHBondContact O-CG2 3.21Å; H285-T289 PolarHBondContact O-N 3.26Å; H285-T289 PolarHBondContact O-OG1 2.93Å
286	P	89.9	Confident	89.4	Confident	15 Å²	15	72.7 Å²	72.7	10%	0.097	37%	0.365	C	S	.	.	H	α-helix	trans	-58.9	-50.5	-171.4	15.4	-26.9	0	0	0	113.5	M282 R288 T289 L290 I367	M282-P286 WeakPolarHBondContact O-CA 2.99Å; M282-P286 WeakPolarHBondContact O-CB 3.43Å; M282-P286 VanDerWaalsContact O-CD 3.26Å; M282-P286 WeakPolarHBondContact O-CD 2.98Å; P286-R288 PolarHBondContact O-N 3.47Å; P286-T289 PolarHBondContact O-N 2.86Å; P286-T289 PolarHBondContact O-OG1 3.35Å; P286-L290 VanDerWaalsContact O-CB 3.28Å; P286-L290 WeakPolarHBondContact O-CB 3.19Å; P286-L290 PolarHBondContact O-N 2.93Å; P286-I367 HydrophobicContact CB-CB 4.36Å; P286-I367 HydrophobicContact CB-CD1 3.71Å; P286-I367 HydrophobicContact CB-CG1 4.01Å; P286-I367 HydrophobicContact CB-CG2 3.43Å; P286-I367 VanDerWaalsContact CB-CG2 3.43Å; P286-I367 HydrophobicContact CG-CG2 3.81Å
287	A	89.8	Confident	89.8	Confident	74 Å²	74	70.7 Å²	70.7	61%	0.612	36%	0.356	S	S	*	.	H	α-helix	trans	-63.9	-46.1	-174.7	0	0	0	0	0	112.4	H285 T289 L291	H285-A287 PolarHBondContact O-N 3.03Å; A287-T289 VanDerWaalsContact C-N 3.3Å; A287-T289 PolarHBondContact O-N 3.38Å; A287-L291 WeakPolarHBondContact O-CB 3.44Å; A287-L291 PolarHBondContact O-N 3.01Å
288	R	91	Very high	90.3	Very high	185 Å²	185	73.2 Å²	73.2	70%	0.698	37%	0.365	S	S	*	.	H	α-helix	trans	-62.3	-40.3	-180	-67.4	-176.5	-177.7	168.4	0	111.7	H285 P286 V292	H285-R288 HydrophobicContact CB-CB 4.47Å; P286-R288 PolarHBondContact O-N 3.47Å; R288-V292 VanDerWaalsContact O-CG2 3.3Å; R288-V292 WeakPolarHBondContact O-CG2 3.47Å; R288-V292 PolarHBondContact O-N 3.45Å; R288-V292 VanDerWaalsContact O-N 3.08Å
289	T	90.6	Very high	90.8	Very high	21 Å²	21	75.1 Å²	75.1	13%	0.129	38%	0.375	C	S	.	.	H	α-helix	trans	-77.7	-38.9	-172.7	55.7	0	0	0	0	111.4	L281 M282 H285 P286 A287 F293	L281-T289 HydrophobicContact CD1-CG2 3.43Å; L281-T289 VanDerWaalsContact CD1-CG2 3.43Å; L281-T289 HydrophobicContact CD2-CG2 3.94Å; L281-T289 HydrophobicContact CG-CG2 3.38Å; M282-T289 HydrophobicContact CE-CG2 4.4Å; M282-T289 WeakPolarHBondContact CE-OG1 3.37Å; H285-T289 HydrophobicContact CB-CG2 4.28Å; H285-T289 WeakPolarHBondContact O-CB 3.47Å; H285-T289 WeakPolarHBondContact O-CG2 3.21Å; H285-T289 PolarHBondContact O-N 3.26Å; H285-T289 PolarHBondContact O-OG1 2.93Å; P286-T289 PolarHBondContact O-N 2.86Å; P286-T289 PolarHBondContact O-OG1 3.35Å; A287-T289 VanDerWaalsContact C-N 3.3Å; A287-T289 PolarHBondContact O-N 3.38Å; T289-F293 WeakPolarHBondContact O-CB 3.39Å; T289-F293 PolarHBondContact O-N 3.48Å; T289-F293 VanDerWaalsContact O-N 3.13Å
290	L	92	Very high	91	Very high	14 Å²	14	70.9 Å²	70.9	7%	0.073	36%	0.36	C	S	.	.	H	α-helix	trans	-65.6	-42.1	171.2	-172.7	148.2	0	0	0	111.6	P286 F293 I294 M363 L364 I367	P286-L290 VanDerWaalsContact O-CB 3.28Å; P286-L290 WeakPolarHBondContact O-CB 3.19Å; P286-L290 PolarHBondContact O-N 2.93Å; L290-F293 PolarHBondContact O-N 3.47Å; L290-I294 HydrophobicContact CD2-CD1 3.38Å; L290-I294 HydrophobicContact CD2-CG1 4.23Å; L290-I294 HydrophobicContact CG-CD1 4.24Å; L290-I294 WeakPolarHBondContact O-CG1 3.35Å; L290-I294 PolarHBondContact O-N 3.39Å; L290-M363 HydrophobicContact CD1-CE 3.71Å; L290-M363 HydrophobicContact CG-CE 4.26Å; L290-L364 HydrophobicContact CD1-CB 4.17Å; L290-L364 HydrophobicContact CD1-CD1 4.35Å; L290-I367 HydrophobicContact CD1-CD1 4.29Å
291	L	92.8	Very high	91.3	Very high	102 Å²	102	68.9 Å²	68.9	53%	0.534	35%	0.349	S	S	.	.	H	α-helix	trans	-61.7	-47.4	177.1	-179.3	147.4	0	0	0	112.3	A287 F293 I294 L295	A287-L291 WeakPolarHBondContact O-CB 3.44Å; A287-L291 PolarHBondContact O-N 3.01Å; L291-F293 VanDerWaalsContact C-N 3.3Å; L291-F293 PolarHBondContact O-N 2.92Å; L291-I294 PolarHBondContact O-N 2.98Å; L291-L295 HydrophobicContact CD2-CD1 3.58Å; L291-L295 HydrophobicContact CD2-CG 4.39Å; L291-L295 HydrophobicContact CG-CD1 4.24Å; L291-L295 WeakPolarHBondContact O-CG 3.45Å; L291-L295 PolarHBondContact O-N 3.37Å
292	V	92.2	Very high	91.6	Very high	81 Å²	81	66.1 Å²	66.1	49%	0.491	34%	0.335	S	S	.	.	H	α-helix	trans	-61.3	-41.5	177.1	169.9	0	0	0	0	110.9	R288 L296	R288-V292 VanDerWaalsContact O-CG2 3.3Å; R288-V292 WeakPolarHBondContact O-CG2 3.47Å; R288-V292 PolarHBondContact O-N 3.45Å; R288-V292 VanDerWaalsContact O-N 3.08Å; V292-L296 HydrophobicContact CG1-CD1 3.81Å; V292-L296 HydrophobicContact CG1-CG 4.4Å; V292-L296 WeakPolarHBondContact O-CB 3.34Å; V292-L296 VanDerWaalsContact O-CG 3.25Å; V292-L296 WeakPolarHBondContact O-CG 3.28Å; V292-L296 PolarHBondContact O-N 3.13Å; V292-L296 VanDerWaalsContact O-N 3.1Å
293	F	92.3	Very high	91.8	Very high	91 Å²	91	65.2 Å²	65.2	40%	0.399	33%	0.329	S	S	.	.	H	α-helix	trans	-61.6	-47.8	176.4	175.9	-97.2	0	0	0	112.3	T289 L290 L291 L296 F297 C360	T289-F293 WeakPolarHBondContact O-CB 3.39Å; T289-F293 PolarHBondContact O-N 3.48Å; T289-F293 VanDerWaalsContact O-N 3.13Å; L290-F293 PolarHBondContact O-N 3.47Å; L291-F293 VanDerWaalsContact C-N 3.3Å; L291-F293 PolarHBondContact O-N 2.92Å; F293-L296 PolarHBondContact O-N 3.42Å; F293-F297 VanDerWaalsContact O-CB 3.25Å; F293-F297 WeakPolarHBondContact O-CB 3.09Å; F293-F297 PolarHBondContact O-N 3.36Å; F293-C360 VanDerWaalsContact CE1-SG 3.5Å
294	I	94.8	Very high	91.9	Very high	31 Å²	31	61.8 Å²	61.8	16%	0.159	31%	0.311	C	S	.	.	H	α-helix	trans	-61.8	-47.3	-179.8	-69.7	177.8	0	0	0	111.1	L290 L291 L296 F297 W298 F331	L290-I294 HydrophobicContact CD2-CD1 3.38Å; L290-I294 HydrophobicContact CD2-CG1 4.23Å; L290-I294 HydrophobicContact CG-CD1 4.24Å; L290-I294 WeakPolarHBondContact O-CG1 3.35Å; L290-I294 PolarHBondContact O-N 3.39Å; L291-I294 PolarHBondContact O-N 2.98Å; I294-L296 PolarHBondContact O-N 3.24Å; I294-F297 PolarHBondContact O-N 3.26Å; I294-W298 HydrophobicContact CG2-CD2 4.01Å; I294-W298 HydrophobicContact CG2-CG 4.28Å; I294-W298 HydrophobicContact CG2-CZ2 3.95Å; I294-W298 WeakPolarHBondContact O-CB 3.4Å; I294-W298 PolarHBondContact O-N 3.03Å; I294-F331 HydrophobicContact CD1-CE1 3.92Å; I294-F331 HydrophobicContact CD1-CZ 4.21Å; I294-F331 HydrophobicContact CG1-CE1 3.99Å; I294-F331 HydrophobicContact CG1-CZ 3.85Å; I294-F331 HydrophobicContact CG2-CE1 4.19Å
295	L	94.5	Very high	91.9	Very high	88 Å²	88	54.8 Å²	54.8	46%	0.461	28%	0.28	S	S	.	.	H	α-helix	trans	-62.7	-44.5	-179.2	-69.2	177	0	0	0	112	L291 F297 W298 L299	L291-L295 HydrophobicContact CD2-CD1 3.58Å; L291-L295 HydrophobicContact CD2-CG 4.39Å; L291-L295 HydrophobicContact CG-CD1 4.24Å; L291-L295 WeakPolarHBondContact O-CG 3.45Å; L291-L295 PolarHBondContact O-N 3.37Å; L295-F297 VanDerWaalsContact C-N 3.34Å; L295-W298 PolarHBondContact O-N 3.39Å; L295-L299 WeakPolarHBondContact O-CG 3.34Å; L295-L299 PolarHBondContact O-N 3.49Å
296	L	92.3	Very high	91.8	Very high	98 Å²	98	51 Å²	51	51%	0.513	26%	0.263	S	S	.	.	H	α-helix	trans	-64.4	-40	176.1	-69.2	174.4	0	0	0	111.7	V292 F293 I294 T300	V292-L296 HydrophobicContact CG1-CD1 3.81Å; V292-L296 HydrophobicContact CG1-CG 4.4Å; V292-L296 WeakPolarHBondContact O-CB 3.34Å; V292-L296 VanDerWaalsContact O-CG 3.25Å; V292-L296 WeakPolarHBondContact O-CG 3.28Å; V292-L296 PolarHBondContact O-N 3.13Å; V292-L296 VanDerWaalsContact O-N 3.1Å; F293-L296 PolarHBondContact O-N 3.42Å; I294-L296 PolarHBondContact O-N 3.24Å; L296-T300 WeakPolarHBondContact O-CB 3.28Å; L296-T300 VanDerWaalsContact O-CG2 3.3Å; L296-T300 WeakPolarHBondContact O-CG2 3.42Å; L296-T300 PolarHBondContact O-N 3.27Å; L296-T300 PolarHBondContact O-OG1 3.17Å
297	F	93.8	Very high	91.5	Very high	23 Å²	23	50.9 Å²	50.9	10%	0.101	26%	0.261	C	S	.	.	H	α-helix	trans	-64.5	-43.8	176.7	-178.1	-105.9	0	0	0	112	F293 I294 L295 T300 A301 F331 F352 T353 M356	F293-F297 VanDerWaalsContact O-CB 3.25Å; F293-F297 WeakPolarHBondContact O-CB 3.09Å; F293-F297 PolarHBondContact O-N 3.36Å; I294-F297 PolarHBondContact O-N 3.26Å; L295-F297 VanDerWaalsContact C-N 3.34Å; F297-T300 WeakPolarHBondContact CA-OG1 3.39Å; F297-T300 PolarHBondContact O-N 3.27Å; F297-T300 PolarHBondContact O-OG1 3.38Å; F297-A301 HydrophobicContact CE1-CB 4.35Å; F297-A301 HydrophobicContact CE2-CB 4.36Å; F297-A301 HydrophobicContact CZ-CB 4.13Å; F297-A301 VanDerWaalsContact O-CB 3.22Å; F297-A301 WeakPolarHBondContact O-CB 3.48Å; F297-A301 PolarHBondContact O-N 3.14Å; F297-F331 AromaticContact CD1-CD2 3.72Å; F297-F331 HydrophobicContact CD1-CD2 3.72Å; F297-F331 AromaticContact CD1-CE2 3.67Å; F297-F331 HydrophobicContact CD1-CE2 3.67Å; F297-F331 AromaticContact CE1-CD2 3.63Å; F297-F331 HydrophobicContact CE1-CD2 3.63Å; F297-F331 AromaticContact CE1-CE2 3.89Å; F297-F331 HydrophobicContact CE1-CE2 3.89Å; F297-F352 HydrophobicContact CE2-CD1 4.02Å; F297-F352 AromaticContact CE2-CE1 3.76Å; F297-F352 HydrophobicContact CE2-CE1 3.76Å; F297-F352 HydrophobicContact CZ-CD1 4.08Å; F297-F352 HydrophobicContact CZ-CE1 4.22Å; F297-T353 HydrophobicContact CE1-CG2 4.02Å; F297-M356 HydrophobicContact CE1-CB 4.23Å; F297-M356 HydrophobicContact CE2-CG 4.45Å; F297-M356 HydrophobicContact CZ-CB 4.08Å; F297-M356 HydrophobicContact CZ-CG 4.3Å
298	W	95.1	Very high	91.3	Very high	56 Å²	56	47.7 Å²	47.7	21%	0.212	24%	0.235	C	C	.	.	H	α-helix	trans	-61.9	-47	177.4	-74.8	7.6	0	0	0	112.1	I294 L295 T300 S302 L324 I327 A328 F331	I294-W298 HydrophobicContact CG2-CD2 4.01Å; I294-W298 HydrophobicContact CG2-CG 4.28Å; I294-W298 HydrophobicContact CG2-CZ2 3.95Å; I294-W298 WeakPolarHBondContact O-CB 3.4Å; I294-W298 PolarHBondContact O-N 3.03Å; L295-W298 PolarHBondContact O-N 3.39Å; W298-T300 PolarHBondContact O-N 3.32Å; W298-S302 WeakPolarHBondContact O-CB 3.32Å; W298-S302 PolarHBondContact O-N 3Å; W298-L324 HydrophobicContact CB-CD1 4.21Å; W298-I327 HydrophobicContact CB-CG2 4.45Å; W298-I327 HydrophobicContact CG-CG2 4.36Å; W298-A328 HydrophobicContact CD2-CB 4.31Å; W298-A328 HydrophobicContact CE3-CB 4.12Å; W298-A328 HydrophobicContact CH2-CB 3.78Å; W298-A328 HydrophobicContact CZ2-CB 3.97Å; W298-A328 HydrophobicContact CZ3-CB 3.86Å; W298-F331 HydrophobicContact CZ2-CD1 4.2Å; W298-F331 AromaticContact NE1-CD1 3.45Å; W298-F331 AromaticContact NE1-CD2 3.92Å; W298-F331 AromaticContact NE1-CG 3.35Å
299	L	92.8	Very high	91	Very high	109 Å²	109	39 Å²	39	57%	0.571	20%	0.202	S	C	*	.	H	α-helix	trans	-62.4	-44.3	178.9	-69.1	172.2	0	0	0	111.8	L295 W303	L295-L299 WeakPolarHBondContact O-CG 3.34Å; L295-L299 PolarHBondContact O-N 3.49Å; L299-W303 WeakPolarHBondContact O-CB 3.19Å; L299-W303 PolarHBondContact O-N 3.11Å
300	T	91.6	Very high	90.3	Very high	38 Å²	38	42.1 Å²	42.1	23%	0.233	21%	0.211	C	C	.	.	H	α-helix	trans	-68.4	-50.4	179.5	51.2	0	0	0	0	111.8	F239 L242 L296 F297 W298 S302 W303 M304	F239-T300 HydrophobicContact CD1-CG2 4.14Å; F239-T300 HydrophobicContact CE1-CG2 4.13Å; L242-T300 HydrophobicContact CD1-CG2 3.81Å; L296-T300 WeakPolarHBondContact O-CB 3.28Å; L296-T300 VanDerWaalsContact O-CG2 3.3Å; L296-T300 WeakPolarHBondContact O-CG2 3.42Å; L296-T300 PolarHBondContact O-N 3.27Å; L296-T300 PolarHBondContact O-OG1 3.17Å; F297-T300 WeakPolarHBondContact CA-OG1 3.39Å; F297-T300 PolarHBondContact O-N 3.27Å; F297-T300 PolarHBondContact O-OG1 3.38Å; W298-T300 PolarHBondContact O-N 3.32Å; T300-S302 VanDerWaalsContact C-N 3.33Å; T300-S302 PolarHBondContact O-N 3Å; T300-W303 PolarHBondContact O-N 3.04Å; T300-M304 VanDerWaalsContact O-CG 3.27Å; T300-M304 WeakPolarHBondContact O-CG 3.31Å; T300-M304 PolarHBondContact O-N 3.5Å
301	A	93.5	Very high	89	Confident	7 Å²	7	47 Å²	47	6%	0.058	23%	0.229	C	C	.	.	H	α-helix	trans	-64.8	-36.1	179.2	0	0	0	0	0	112.5	F297 M304 L305 I327 V349	F297-A301 HydrophobicContact CE1-CB 4.35Å; F297-A301 HydrophobicContact CE2-CB 4.36Å; F297-A301 HydrophobicContact CZ-CB 4.13Å; F297-A301 VanDerWaalsContact O-CB 3.22Å; F297-A301 WeakPolarHBondContact O-CB 3.48Å; F297-A301 PolarHBondContact O-N 3.14Å; A301-M304 PolarHBondContact O-N 3.41Å; A301-L305 VanDerWaalsContact O-CB 3.32Å; A301-L305 WeakPolarHBondContact O-CB 3.32Å; A301-L305 PolarHBondContact O-N 2.95Å; A301-I327 HydrophobicContact CB-CD1 3.97Å; A301-I327 HydrophobicContact CB-CG1 4.27Å; A301-I327 HydrophobicContact CB-CG2 4Å; A301-V349 HydrophobicContact CB-CG1 4.4Å
302	S	92.9	Very high	87.6	Confident	1 Å²	1	43.9 Å²	43.9	1%	0.007	22%	0.215	C	C	.	.	H	α-helix	trans	-61.7	-49.2	173.8	-178.9	0	0	0	0	110.7	W298 T300 M304 L305 T306 M320 L324	W298-S302 WeakPolarHBondContact O-CB 3.32Å; W298-S302 PolarHBondContact O-N 3Å; T300-S302 VanDerWaalsContact C-N 3.33Å; T300-S302 PolarHBondContact O-N 3Å; S302-M304 VanDerWaalsContact C-N 3.34Å; S302-M304 PolarHBondContact O-N 3.33Å; S302-L305 PolarHBondContact O-N 3.47Å; S302-T306 PolarHBondContact O-N 3.36Å; S302-T306 PolarHBondContact O-OG1 3.45Å; S302-M320 PolarHBondContact OG-O 2.81Å; S302-M320 PolarHBondContact OG-SD 2.64Å; S302-M320 VanDerWaalsContact OG-SD 3.38Å; S302-L324 VanDerWaalsContact OG-CA 3.26Å; S302-L324 WeakPolarHBondContact OG-CA 3.4Å; S302-L324 PolarHBondContact OG-N 2.84Å
303	W	90.1	Very high	85.8	Confident	11 Å²	11	49.3 Å²	49.3	4%	0.042	24%	0.235	C	C	.	.	H	α-helix	trans	-62.8	-41.2	178.7	-170.7	91.1	0	0	0	112.1	M119 I120 A123 F239 L299 T300 L305 T306 L307 M320	M119-W303 HydrophobicContact CE-CE3 4.45Å; M119-W303 HydrophobicContact CE-CH2 2.99Å; M119-W303 HydrophobicContact CE-CZ2 3.3Å; M119-W303 HydrophobicContact CE-CZ3 3.68Å; M119-W303 HydrophobicContact SD-CH2 3.63Å; M119-W303 HydrophobicContact SD-CZ2 4.38Å; M119-W303 HydrophobicContact SD-CZ3 4.29Å; I120-W303 HydrophobicContact CB-CZ2 4.35Å; I120-W303 HydrophobicContact CG1-CD2 4.12Å; I120-W303 HydrophobicContact CG1-CG 4.46Å; I120-W303 HydrophobicContact CG1-CZ2 3.87Å; A123-W303 HydrophobicContact CB-CZ2 3.94Å; F239-W303 HydrophobicContact CD2-CE3 4.41Å; F239-W303 HydrophobicContact CD2-CZ3 4.11Å; F239-W303 HydrophobicContact CE1-CE3 4.25Å; F239-W303 HydrophobicContact CE2-CD2 4.32Å; F239-W303 AromaticContact CE2-CE3 3.3Å; F239-W303 HydrophobicContact CE2-CE3 3.3Å; F239-W303 AromaticContact CE2-CH2 3.92Å; F239-W303 HydrophobicContact CE2-CH2 3.92Å; F239-W303 AromaticContact CE2-CZ3 3.07Å; F239-W303 HydrophobicContact CE2-CZ3 3.07Å; F239-W303 AromaticContact CZ-CD2 3.86Å; F239-W303 HydrophobicContact CZ-CD2 3.86Å; F239-W303 AromaticContact CZ-CE3 3.17Å; F239-W303 HydrophobicContact CZ-CE3 3.17Å; F239-W303 HydrophobicContact CZ-CH2 4.33Å; F239-W303 AromaticContact CZ-CZ3 3.49Å; F239-W303 HydrophobicContact CZ-CZ3 3.49Å; F239-W303 VanDerWaalsContact CZ-CZ3 3.49Å; L299-W303 WeakPolarHBondContact O-CB 3.19Å; L299-W303 PolarHBondContact O-N 3.11Å; T300-W303 PolarHBondContact O-N 3.04Å; W303-L305 VanDerWaalsContact C-N 3.34Å; W303-L305 PolarHBondContact O-N 3.01Å; W303-T306 WeakPolarHBondContact O-CB 3.48Å; W303-T306 PolarHBondContact O-N 2.96Å; W303-L307 HydrophobicContact CH2-CB 4.45Å; W303-L307 HydrophobicContact CH2-CD1 4.22Å; W303-L307 HydrophobicContact CH2-CD2 3.62Å; W303-L307 HydrophobicContact CH2-CG 4.26Å; W303-L307 HydrophobicContact CZ2-CD1 4.45Å; W303-L307 HydrophobicContact CZ3-CB 4.29Å; W303-L307 HydrophobicContact CZ3-CD2 3.62Å; W303-L307 HydrophobicContact CZ3-CG 4.39Å; W303-L307 WeakPolarHBondContact O-CB 3.36Å; W303-L307 PolarHBondContact O-N 3.42Å; W303-M320 HydrophobicContact CB-CE 4.09Å; W303-M320 HydrophobicContact CB-SD 4.37Å; W303-M320 HydrophobicContact CG-CE 4.01Å
304	M	89.6	Confident	84.1	Confident	24 Å²	24	46.7 Å²	46.7	12%	0.118	23%	0.228	C	C	.	.	H	α-helix	trans	-60.4	-41.7	173.5	-69.9	-41.8	-147.6	0	0	113.2	M236 F239 T300 A301 S302 L307 C308 V349	M236-M304 HydrophobicContact CB-CE 4.34Å; M236-M304 HydrophobicContact CE-CB 3.84Å; M236-M304 HydrophobicContact CE-CE 3.95Å; M236-M304 HydrophobicContact CE-CG 3.89Å; M236-M304 HydrophobicContact CE-SD 3.66Å; M236-M304 VanDerWaalsContact O-CE 3.3Å; M236-M304 WeakPolarHBondContact O-CE 3.38Å; M236-M304 HydrophobicContact SD-CB 4.07Å; M236-M304 HydrophobicContact SD-CE 3.99Å; M236-M304 HydrophobicContact SD-CG 4.11Å; M236-M304 HydrophobicContact SD-SD 3.23Å; F239-M304 HydrophobicContact CB-CE 3.32Å; F239-M304 HydrophobicContact CD1-CE 3.99Å; F239-M304 HydrophobicContact CD2-CE 3.11Å; F239-M304 HydrophobicContact CD2-SD 3.65Å; F239-M304 HydrophobicContact CE2-CE 3.89Å; F239-M304 HydrophobicContact CE2-SD 3.79Å; F239-M304 HydrophobicContact CG-CE 3.18Å; F239-M304 HydrophobicContact CG-SD 4.06Å; F239-M304 HydrophobicContact CZ-SD 4.29Å; T300-M304 VanDerWaalsContact O-CG 3.27Å; T300-M304 WeakPolarHBondContact O-CG 3.31Å; T300-M304 PolarHBondContact O-N 3.5Å; A301-M304 PolarHBondContact O-N 3.41Å; S302-M304 VanDerWaalsContact C-N 3.34Å; S302-M304 PolarHBondContact O-N 3.33Å; M304-L307 PolarHBondContact O-N 3.19Å; M304-C308 PolarHBondContact O-N 3.11Å; M304-V349 HydrophobicContact CB-CG1 4.45Å; M304-V349 HydrophobicContact CB-CG2 4.36Å
305	L	90.2	Very high	82.3	Confident	0 Å²	0	52.6 Å²	52.6	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-67.3	-45.6	179.2	-177.8	63.1	0	0	0	111.2	A301 S302 W303 L307 C308 E309 A323 L326 I327 P341 V349	A301-L305 VanDerWaalsContact O-CB 3.32Å; A301-L305 WeakPolarHBondContact O-CB 3.32Å; A301-L305 PolarHBondContact O-N 2.95Å; S302-L305 PolarHBondContact O-N 3.47Å; W303-L305 VanDerWaalsContact C-N 3.34Å; W303-L305 PolarHBondContact O-N 3.01Å; L305-L307 VanDerWaalsContact C-N 3.26Å; L305-L307 PolarHBondContact O-N 3.4Å; L305-C308 PolarHBondContact O-N 3.48Å; L305-E309 HydrophobicContact CD1-CG 4.01Å; L305-E309 PolarHBondContact O-N 3.26Å; L305-A323 HydrophobicContact CB-CB 4.43Å; L305-A323 HydrophobicContact CD2-CB 4.23Å; L305-A323 HydrophobicContact CG-CB 4.42Å; L305-L326 HydrophobicContact CD2-CB 4.3Å; L305-L326 HydrophobicContact CD2-CD2 3.69Å; L305-L326 HydrophobicContact CD2-CG 4.01Å; L305-I327 HydrophobicContact CB-CD1 4.4Å; L305-I327 HydrophobicContact CD2-CD1 3.88Å; L305-I327 HydrophobicContact CD2-CG1 3.93Å; L305-P341 HydrophobicContact CD1-CB 4.23Å; L305-V349 HydrophobicContact CB-CG1 4.32Å
306	T	87.1	Confident	80.7	Confident	2 Å²	2	53 Å²	53	1%	0.012	27%	0.266	C	S	.	.	H	α-helix	trans	-53.6	-46.6	172.7	-57.9	0	0	0	0	110.6	S302 W303 C308 E309 R310 G318 M320 A323	S302-T306 PolarHBondContact O-N 3.36Å; S302-T306 PolarHBondContact O-OG1 3.45Å; W303-T306 WeakPolarHBondContact O-CB 3.48Å; W303-T306 PolarHBondContact O-N 2.96Å; T306-C308 PolarHBondContact O-N 3.15Å; T306-E309 PolarHBondContact O-N 3.31Å; T306-R310 WeakPolarHBondContact O-CB 3.13Å; T306-R310 PolarHBondContact O-N 3.43Å; T306-G318 WeakPolarHBondContact CG2-O 3.16Å; T306-M320 HydrophobicContact CG2-CE 4.08Å; T306-A323 WeakPolarHBondContact OG1-CB 2.95Å
307	L	83.4	Confident	79.3	Confident	13 Å²	13	48.7 Å²	48.7	7%	0.068	24%	0.243	C	C	.	.	H	α-helix	trans	-64.6	-41.8	-178.9	-171.5	70.3	0	0	0	111.6	A123 L232 M236 W303 M304 L305	A123-L307 HydrophobicContact CB-CD1 4.49Å; L232-L307 HydrophobicContact CD1-CB 4.44Å; L232-L307 HydrophobicContact CD1-CD1 3.87Å; L232-L307 HydrophobicContact CD1-CD2 3.65Å; L232-L307 HydrophobicContact CD1-CG 3.33Å; L232-L307 WeakPolarHBondContact CD1-O 3.48Å; M236-L307 HydrophobicContact CG-CD2 3.96Å; M236-L307 HydrophobicContact SD-CD2 3.78Å; W303-L307 HydrophobicContact CH2-CB 4.45Å; W303-L307 HydrophobicContact CH2-CD1 4.22Å; W303-L307 HydrophobicContact CH2-CD2 3.62Å; W303-L307 HydrophobicContact CH2-CG 4.26Å; W303-L307 HydrophobicContact CZ2-CD1 4.45Å; W303-L307 HydrophobicContact CZ3-CB 4.29Å; W303-L307 HydrophobicContact CZ3-CD2 3.62Å; W303-L307 HydrophobicContact CZ3-CG 4.39Å; W303-L307 WeakPolarHBondContact O-CB 3.36Å; W303-L307 PolarHBondContact O-N 3.42Å; M304-L307 PolarHBondContact O-N 3.19Å; L305-L307 VanDerWaalsContact C-N 3.26Å; L305-L307 PolarHBondContact O-N 3.4Å
308	C	85.6	Confident	77.9	Confident	7 Å²	7	48.7 Å²	48.7	5%	0.047	25%	0.25	C	C	.	.	H	α-helix	trans	-72.5	-34.1	178.4	-79.8	0	0	0	0	114.3	M304 L305 T306 T343 C345	M304-C308 PolarHBondContact O-N 3.11Å; L305-C308 PolarHBondContact O-N 3.48Å; T306-C308 PolarHBondContact O-N 3.15Å; C308-T343 WeakPolarHBondContact O-CG2 3.29Å; C308-C345 HydrophobicContact CB-CB 3.6Å; C308-C345 WeakPolarHBondContact CB-SG 3.34Å; C308-C345 WeakPolarHBondContact SG-CB 3.42Å; C308-C345 CovalentContact SG-SG 2.03Å; C308-C345 PolarHBondContact SG-SG 3.49Å
309	E	84.6	Confident	77.2	Confident	1 Å²	1	51.2 Å²	51.2	1%	0.005	26%	0.264	C	S	.	.	H	α-helix	trans	-88.8	-8	-180	-65	-66.9	141.4	0	0	113.5	L305 T306 R311 S312 T317 P341 K342 T343	L305-E309 HydrophobicContact CD1-CG 4.01Å; L305-E309 PolarHBondContact O-N 3.26Å; T306-E309 PolarHBondContact O-N 3.31Å; E309-R311 PolarHBondContact O-N 2.82Å; E309-S312 PolarHBondContact O-N 2.91Å; E309-T317 HydrophobicContact CB-CG2 4.3Å; E309-T317 HydrophobicContact CG-CG2 4.11Å; E309-P341 WeakPolarHBondContact OE1-CB 3.45Å; E309-K342 PolarHBondContact OE1-N 2.96Å; E309-K342 VanDerWaalsContact OE1-N 3.15Å; E309-K342 PolarHBondContact OE2-N 3.21Å; E309-T343 VanDerWaalsContact OE1-CB 3.3Å; E309-T343 WeakPolarHBondContact OE1-CB 3.29Å; E309-T343 PolarHBondContact OE1-N 3.36Å; E309-T343 PolarHBondContact OE1-OG1 3.48Å
310	R	75.6	Confident	76.8	Confident	88 Å²	88	49.3 Å²	49.3	33%	0.332	25%	0.253	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.6	-24.3	178	-174.9	170.4	-73.4	174.2	-6	114.1	A123 E124 T306	A123-R310 PolarHBondContact O-NH1 3.34Å; E124-R310 VanDerWaalsContact CD-NH2 3.28Å; E124-R310 IonicContact OE1-CZ 2.56Å; E124-R310 IonicContact OE1-NH2 3.98Å; E124-R310 PolarHBondContact OE1-NH2 2.8Å; E124-R310 IonicContact OE2-NH2 3.94Å; E124-R310 PolarHBondContact OE2-NH2 2.59Å; T306-R310 WeakPolarHBondContact O-CB 3.13Å; T306-R310 PolarHBondContact O-N 3.43Å
311	R	63.6	Low	76.6	Confident	117 Å²	117	52.4 Å²	52.4	44%	0.442	27%	0.268	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88.1	-17.4	-179.4	-173.2	170.5	177.6	139.9	2.2	114	D229 E309	D229-R311 VanDerWaalsContact CG-NH1 3.3Å; D229-R311 IonicContact OD1-CZ 2.73Å; D229-R311 IonicContact OD1-NH1 3.32Å; D229-R311 PolarHBondContact OD1-NH1 2.7Å; D229-R311 IonicContact OD2-NH1 3.01Å; D229-R311 PolarHBondContact OD2-NH1 2.96Å; E309-R311 PolarHBondContact O-N 2.82Å
312	S	64.3	Low	76.5	Confident	35 Å²	35	53.4 Å²	53.4	25%	0.245	27%	0.273	C	S	.	.	S	Bend	trans	-75.5	131.3	179.1	-175.7	0	0	0	0	109.3	E309 S314	E309-S312 PolarHBondContact O-N 2.91Å; S312-S314 PolarHBondContact O-N 2.76Å; S312-S314 PolarHBondContact OG-OG 3.31Å
313	E	54.7	Low	76.4	Confident	196 Å²	196	53.3 Å²	53.3	92%	0.916	27%	0.273	S	S	*	.	S	Bend	trans	-59.6	-6.9	177.9	-68.2	178.6	166.9	0	0	113.7	L315	E313-L315 PolarHBondContact O-N 3.49Å
314	S	55.6	Low	76.6	Confident	36 Å²	36	55.9 Å²	55.9	25%	0.252	29%	0.287	S	S	.	.			trans	-75.4	89.2	172.6	60.2	0	0	0	0	111.7	S312 T316 T317	S312-S314 PolarHBondContact O-N 2.76Å; S312-S314 PolarHBondContact OG-OG 3.31Å; S314-T316 PolarHBondContact O-N 2.91Å; S314-T317 PolarHBondContact O-N 3.26Å
315	L	57	Low	76.8	Confident	155 Å²	155	60.7 Å²	60.7	81%	0.812	30%	0.304	S	S	*	.	T	Hydrogen-bonded Turn	trans	-49.8	-21.4	179.6	-110.6	119.4	0	0	0	115.8	E313	E313-L315 PolarHBondContact O-N 3.49Å
316	T	61.9	Low	77	Confident	97 Å²	97	61 Å²	61	60%	0.595	31%	0.306	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.8	-29.3	-173.8	50.6	0	0	0	0	114.5	S314 T322	S314-T316 PolarHBondContact O-N 2.91Å; T316-T322 WeakPolarHBondContact O-CB 3.1Å; T316-T322 VanDerWaalsContact O-CG2 3.32Å; T316-T322 WeakPolarHBondContact O-CG2 3.44Å; T316-T322 PolarHBondContact O-OG1 3.41Å
317	T	61.7	Low	77.4	Confident	7 Å²	7	61 Å²	61	4%	0.043	31%	0.305	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89.3	-18.9	-176.2	-51.7	0	0	0	0	113	E309 S314 Q319 V339	E309-T317 HydrophobicContact CB-CG2 4.3Å; E309-T317 HydrophobicContact CG-CG2 4.11Å; S314-T317 PolarHBondContact O-N 3.26Å; T317-Q319 VanDerWaalsContact C-N 3.29Å; T317-Q319 PolarHBondContact O-N 3.14Å; T317-V339 HydrophobicContact CG2-CG1 3.7Å; T317-V339 WeakPolarHBondContact OG1-CG1 3.37Å
318	G	64.5	Low	78	Confident	23 Å²	23	61 Å²	61	24%	0.237	31%	0.307	C	S	.	.	S	Bend	trans	-81.4	4.4	-176.9	0	0	0	0	0	115.6	T306	T306-G318 WeakPolarHBondContact CG2-O 3.16Å
319	Q	80.8	Confident	78.5	Confident	108 Å²	108	61 Å²	61	51%	0.505	31%	0.307	S	S	.	.	S	Bend	trans	-93.8	144.9	176.4	-61.8	-176.6	-48.7	0	0	111.3	T317 D321 T322 A323	T317-Q319 VanDerWaalsContact C-N 3.29Å; T317-Q319 PolarHBondContact O-N 3.14Å; Q319-D321 VanDerWaalsContact C-N 3.33Å; Q319-D321 WeakPolarHBondContact CB-OD1 3.19Å; Q319-D321 PolarHBondContact O-N 3.37Å; Q319-T322 PolarHBondContact O-N 2.97Å; Q319-A323 WeakPolarHBondContact O-CB 3.41Å; Q319-A323 PolarHBondContact O-N 2.8Å
320	M	84.8	Confident	79	Confident	70 Å²	70	62.3 Å²	62.3	35%	0.345	32%	0.315	S	S	.	.	H	α-helix	trans	-62.9	-36.4	-174.4	-171.3	62	65	0	0	113.5	S302 W303 T306 L324	S302-M320 PolarHBondContact OG-O 2.81Å; S302-M320 PolarHBondContact OG-SD 2.64Å; S302-M320 VanDerWaalsContact OG-SD 3.38Å; W303-M320 HydrophobicContact CB-CE 4.09Å; W303-M320 HydrophobicContact CB-SD 4.37Å; W303-M320 HydrophobicContact CG-CE 4.01Å; T306-M320 HydrophobicContact CG2-CE 4.08Å; M320-L324 VanDerWaalsContact O-CB 3.24Å; M320-L324 WeakPolarHBondContact O-CB 3.44Å; M320-L324 PolarHBondContact O-N 3.14Å
321	D	88	Confident	80.1	Confident	103 Å²	103	58.4 Å²	58.4	55%	0.551	30%	0.3	S	S	*	.	H	α-helix	trans	-64.2	-44.2	178.1	59.3	-22.3	0	0	0	111.7	Q319 L324 W325	Q319-D321 VanDerWaalsContact C-N 3.33Å; Q319-D321 WeakPolarHBondContact CB-OD1 3.19Å; Q319-D321 PolarHBondContact O-N 3.37Å; D321-L324 PolarHBondContact O-N 3.24Å; D321-W325 WeakPolarHBondContact O-CB 3.16Å; D321-W325 PolarHBondContact O-N 2.66Å
322	T	89.9	Confident	81.6	Confident	27 Å²	27	57.3 Å²	57.3	17%	0.166	30%	0.303	C	S	.	.	H	α-helix	trans	-70.4	-39.8	178.1	-60.6	0	0	0	0	111.2	T316 Q319 W325 L326 V339	T316-T322 WeakPolarHBondContact O-CB 3.1Å; T316-T322 VanDerWaalsContact O-CG2 3.32Å; T316-T322 WeakPolarHBondContact O-CG2 3.44Å; T316-T322 PolarHBondContact O-OG1 3.41Å; Q319-T322 PolarHBondContact O-N 2.97Å; T322-W325 PolarHBondContact O-N 2.87Å; T322-L326 WeakPolarHBondContact O-CB 3.44Å; T322-L326 PolarHBondContact O-N 2.83Å; T322-V339 HydrophobicContact CG2-CB 4.26Å; T322-V339 HydrophobicContact CG2-CG1 3.75Å; T322-V339 HydrophobicContact CG2-CG2 3.81Å
323	A	91.4	Very high	83.1	Confident	0 Å²	0	60 Å²	60	0%	0	32%	0.318	C	S	.	.	H	α-helix	trans	-63.8	-40.3	172.9	0	0	0	0	0	111.8	L305 T306 Q319 L326 I327	L305-A323 HydrophobicContact CB-CB 4.43Å; L305-A323 HydrophobicContact CD2-CB 4.23Å; L305-A323 HydrophobicContact CG-CB 4.42Å; T306-A323 WeakPolarHBondContact OG1-CB 2.95Å; Q319-A323 WeakPolarHBondContact O-CB 3.41Å; Q319-A323 PolarHBondContact O-N 2.8Å; A323-L326 PolarHBondContact O-N 3.42Å; A323-I327 WeakPolarHBondContact O-CB 3.43Å; A323-I327 VanDerWaalsContact O-CG1 3.29Å; A323-I327 WeakPolarHBondContact O-CG1 3.22Å; A323-I327 PolarHBondContact O-N 3.47Å
324	L	93.4	Very high	85.1	Confident	65 Å²	65	54.2 Å²	54.2	34%	0.34	30%	0.296	S	S	.	.	H	α-helix	trans	-65.3	-43.9	177.9	-177.5	66.2	0	0	0	110.9	W298 S302 M320 D321 I327 A328	W298-L324 HydrophobicContact CB-CD1 4.21Å; S302-L324 VanDerWaalsContact OG-CA 3.26Å; S302-L324 WeakPolarHBondContact OG-CA 3.4Å; S302-L324 PolarHBondContact OG-N 2.84Å; M320-L324 VanDerWaalsContact O-CB 3.24Å; M320-L324 WeakPolarHBondContact O-CB 3.44Å; M320-L324 PolarHBondContact O-N 3.14Å; D321-L324 PolarHBondContact O-N 3.24Å; L324-I327 PolarHBondContact O-N 3Å; L324-A328 WeakPolarHBondContact O-CB 3.38Å; L324-A328 PolarHBondContact O-N 3.46Å
325	W	94.2	Very high	86.9	Confident	125 Å²	125	55 Å²	55	47%	0.473	31%	0.31	S	S	.	.	H	α-helix	trans	-56.7	-51.7	172.2	172.4	-109	0	0	0	111.3	D321 T322 I327 A328 I329 Y336 D338	D321-W325 WeakPolarHBondContact O-CB 3.16Å; D321-W325 PolarHBondContact O-N 2.66Å; T322-W325 PolarHBondContact O-N 2.87Å; W325-I327 PolarHBondContact O-N 3.38Å; W325-A328 PolarHBondContact O-N 2.98Å; W325-I329 HydrophobicContact CD2-CG2 4.13Å; W325-I329 HydrophobicContact CE3-CG2 4.35Å; W325-I329 HydrophobicContact CH2-CG2 4.18Å; W325-I329 HydrophobicContact CZ2-CG2 3.93Å; W325-I329 HydrophobicContact CZ3-CG2 4.38Å; W325-I329 WeakPolarHBondContact O-CG1 3.43Å; W325-I329 PolarHBondContact O-N 3.36Å; W325-Y336 HydrophobicContact CH2-CE2 4.16Å; W325-Y336 AromaticContact CZ2-CD2 3.91Å; W325-Y336 HydrophobicContact CZ2-CD2 3.91Å; W325-Y336 AromaticContact CZ2-CE2 3.92Å; W325-Y336 HydrophobicContact CZ2-CE2 3.92Å; W325-D338 PolarHBondContact NE1-OD2 2.77Å
326	L	94.2	Very high	88.6	Confident	7 Å²	7	55.3 Å²	55.3	4%	0.037	30%	0.301	C	S	.	.	H	α-helix	trans	-60.5	-42.9	-179.8	178.6	53.9	0	0	0	112.4	L305 T322 A323 I329 T330 V339	L305-L326 HydrophobicContact CD2-CB 4.3Å; L305-L326 HydrophobicContact CD2-CD2 3.69Å; L305-L326 HydrophobicContact CD2-CG 4.01Å; T322-L326 WeakPolarHBondContact O-CB 3.44Å; T322-L326 PolarHBondContact O-N 2.83Å; A323-L326 PolarHBondContact O-N 3.42Å; L326-I329 HydrophobicContact CD1-CD1 4.15Å; L326-I329 HydrophobicContact CD1-CG1 4.33Å; L326-I329 VanDerWaalsContact O-CG1 3.23Å; L326-I329 WeakPolarHBondContact O-CG1 3.35Å; L326-T330 WeakPolarHBondContact O-CB 3.4Å; L326-T330 PolarHBondContact O-N 3.17Å; L326-T330 PolarHBondContact O-OG1 3.25Å; L326-V339 WeakPolarHBondContact CD1-O 3.22Å; L326-V339 HydrophobicContact CD2-CG1 4.1Å
327	I	95.9	Very high	89.9	Confident	0 Å²	0	53.7 Å²	53.7	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-65.9	-42.8	176.8	-70.7	-61.8	0	0	0	111.3	W298 A301 L305 A323 L324 W325 T330 F331 V349 T353	W298-I327 HydrophobicContact CB-CG2 4.45Å; W298-I327 HydrophobicContact CG-CG2 4.36Å; A301-I327 HydrophobicContact CB-CD1 3.97Å; A301-I327 HydrophobicContact CB-CG1 4.27Å; A301-I327 HydrophobicContact CB-CG2 4Å; L305-I327 HydrophobicContact CB-CD1 4.4Å; L305-I327 HydrophobicContact CD2-CD1 3.88Å; L305-I327 HydrophobicContact CD2-CG1 3.93Å; A323-I327 WeakPolarHBondContact O-CB 3.43Å; A323-I327 VanDerWaalsContact O-CG1 3.29Å; A323-I327 WeakPolarHBondContact O-CG1 3.22Å; A323-I327 PolarHBondContact O-N 3.47Å; L324-I327 PolarHBondContact O-N 3Å; W325-I327 PolarHBondContact O-N 3.38Å; I327-T330 PolarHBondContact O-N 3.05Å; I327-F331 WeakPolarHBondContact O-CB 3.19Å; I327-F331 PolarHBondContact O-N 3.43Å; I327-V349 HydrophobicContact CD1-CG1 4.19Å; I327-T353 HydrophobicContact CD1-CG2 4.08Å; I327-T353 HydrophobicContact CG2-CG2 4.04Å
328	A	95.9	Very high	91.3	Very high	14 Å²	14	57.8 Å²	57.8	12%	0.116	33%	0.326	C	S	.	.	H	α-helix	trans	-62.1	-47.9	178.6	0	0	0	0	0	111.9	W298 L324 W325 T330 F331 L332	W298-A328 HydrophobicContact CD2-CB 4.31Å; W298-A328 HydrophobicContact CE3-CB 4.12Å; W298-A328 HydrophobicContact CH2-CB 3.78Å; W298-A328 HydrophobicContact CZ2-CB 3.97Å; W298-A328 HydrophobicContact CZ3-CB 3.86Å; L324-A328 WeakPolarHBondContact O-CB 3.38Å; L324-A328 PolarHBondContact O-N 3.46Å; W325-A328 PolarHBondContact O-N 2.98Å; A328-T330 VanDerWaalsContact C-N 3.34Å; A328-T330 PolarHBondContact O-N 3.03Å; A328-F331 PolarHBondContact O-N 3.17Å; A328-L332 WeakPolarHBondContact O-CB 3.46Å; A328-L332 WeakPolarHBondContact O-CG 3.41Å; A328-L332 PolarHBondContact O-N 2.94Å
329	I	95.8	Very high	92.4	Very high	8 Å²	8	58 Å²	58	4%	0.041	32%	0.322	C	S	.	.	H	α-helix	trans	-67.8	-33.3	178.7	66.6	178.3	0	0	0	112.3	W325 L326 T333 V334 Y336	W325-I329 HydrophobicContact CD2-CG2 4.13Å; W325-I329 HydrophobicContact CE3-CG2 4.35Å; W325-I329 HydrophobicContact CH2-CG2 4.18Å; W325-I329 HydrophobicContact CZ2-CG2 3.93Å; W325-I329 HydrophobicContact CZ3-CG2 4.38Å; W325-I329 WeakPolarHBondContact O-CG1 3.43Å; W325-I329 PolarHBondContact O-N 3.36Å; L326-I329 HydrophobicContact CD1-CD1 4.15Å; L326-I329 HydrophobicContact CD1-CG1 4.33Å; L326-I329 VanDerWaalsContact O-CG1 3.23Å; L326-I329 WeakPolarHBondContact O-CG1 3.35Å; I329-T333 PolarHBondContact O-N 3.31Å; I329-V334 PolarHBondContact O-N 2.94Å; I329-Y336 HydrophobicContact CD1-CD2 4.32Å; I329-Y336 HydrophobicContact CG2-CD2 4.03Å; I329-Y336 HydrophobicContact CG2-CE2 4.06Å
330	T	96.6	Very high	92.9	Very high	28 Å²	28	54.8 Å²	54.8	17%	0.172	31%	0.314	C	S	.	.	H	α-helix	trans	-71.1	-42.7	176.9	-58.3	0	0	0	0	110.8	L326 I327 A328 L332 T333 C350 T353	L326-T330 WeakPolarHBondContact O-CB 3.4Å; L326-T330 PolarHBondContact O-N 3.17Å; L326-T330 PolarHBondContact O-OG1 3.25Å; I327-T330 PolarHBondContact O-N 3.05Å; A328-T330 VanDerWaalsContact C-N 3.34Å; A328-T330 PolarHBondContact O-N 3.03Å; T330-L332 VanDerWaalsContact C-N 3.32Å; T330-L332 PolarHBondContact O-N 3.47Å; T330-T333 WeakPolarHBondContact O-CA 3.23Å; T330-T333 PolarHBondContact O-N 3.45Å; T330-C350 HydrophobicContact CG2-CB 4.27Å; T330-C350 WeakPolarHBondContact CG2-O 3.44Å; T330-T353 HydrophobicContact CG2-CG2 4.02Å
331	F	97.1	Very high	93.1	Very high	5 Å²	5	52.5 Å²	52.5	2%	0.022	30%	0.304	C	S	.	.	H	α-helix	trans	-63.9	-38.4	177	-174.2	-91.3	0	0	0	111.9	I294 F297 W298 I327 A328 T333 T353 M356 G357 C360	I294-F331 HydrophobicContact CD1-CE1 3.92Å; I294-F331 HydrophobicContact CD1-CZ 4.21Å; I294-F331 HydrophobicContact CG1-CE1 3.99Å; I294-F331 HydrophobicContact CG1-CZ 3.85Å; I294-F331 HydrophobicContact CG2-CE1 4.19Å; F297-F331 AromaticContact CD1-CD2 3.72Å; F297-F331 HydrophobicContact CD1-CD2 3.72Å; F297-F331 AromaticContact CD1-CE2 3.67Å; F297-F331 HydrophobicContact CD1-CE2 3.67Å; F297-F331 AromaticContact CE1-CD2 3.63Å; F297-F331 HydrophobicContact CE1-CD2 3.63Å; F297-F331 AromaticContact CE1-CE2 3.89Å; F297-F331 HydrophobicContact CE1-CE2 3.89Å; W298-F331 HydrophobicContact CZ2-CD1 4.2Å; W298-F331 AromaticContact NE1-CD1 3.45Å; W298-F331 AromaticContact NE1-CD2 3.92Å; W298-F331 AromaticContact NE1-CG 3.35Å; I327-F331 WeakPolarHBondContact O-CB 3.19Å; I327-F331 PolarHBondContact O-N 3.43Å; A328-F331 PolarHBondContact O-N 3.17Å; F331-T333 PolarHBondContact O-N 3.01Å; F331-T353 HydrophobicContact CB-CG2 3.91Å; F331-T353 HydrophobicContact CD2-CG2 4.38Å; F331-M356 HydrophobicContact CE2-CB 4.33Å; F331-G357 WeakPolarHBondContact O-CA 3.39Å; F331-C360 HydrophobicContact CE1-CB 4.24Å; F331-C360 HydrophobicContact CE2-CB 4.49Å; F331-C360 HydrophobicContact CZ-CB 3.62Å
332	L	96	Very high	93.1	Very high	95 Å²	95	53.9 Å²	53.9	50%	0.497	31%	0.306	S	S	.	.	T	Hydrogen-bonded Turn	trans	-78.5	0.8	173.8	-67.3	171	0	0	0	113.1	A328 T330 V334	A328-L332 WeakPolarHBondContact O-CB 3.46Å; A328-L332 WeakPolarHBondContact O-CG 3.41Å; A328-L332 PolarHBondContact O-N 2.94Å; T330-L332 VanDerWaalsContact C-N 3.32Å; T330-L332 PolarHBondContact O-N 3.47Å; L332-V334 HydrophobicContact CB-CG2 3.97Å; L332-V334 PolarHBondContact O-N 2.99Å
333	T	96.1	Very high	93	Very high	90 Å²	90	54.3 Å²	54.3	55%	0.552	31%	0.308	S	S	*	.	T	Hydrogen-bonded Turn	trans	56.9	29.3	-179.8	62.3	0	0	0	0	114	I329 T330 F331 V358	I329-T333 PolarHBondContact O-N 3.31Å; T330-T333 WeakPolarHBondContact O-CA 3.23Å; T330-T333 PolarHBondContact O-N 3.45Å; F331-T333 PolarHBondContact O-N 3.01Å; T333-V358 HydrophobicContact CG2-CG2 3.89Å
334	V	96.4	Very high	92.8	Very high	75 Å²	75	59.4 Å²	59.4	46%	0.455	34%	0.344	S	S	.	.			trans	-82.4	-55.7	178.3	-179.9	0	0	0	0	110.7	I329 L332 Y336	I329-V334 PolarHBondContact O-N 2.94Å; L332-V334 HydrophobicContact CB-CG2 3.97Å; L332-V334 PolarHBondContact O-N 2.99Å; V334-Y336 HydrophobicContact CG1-CD1 4.06Å; V334-Y336 HydrophobicContact CG1-CD2 4.12Å; V334-Y336 HydrophobicContact CG1-CE1 3.7Å; V334-Y336 HydrophobicContact CG1-CE2 3.76Å; V334-Y336 HydrophobicContact CG1-CG 4.26Å
335	G	93.7	Very high	92.5	Very high	53 Å²	53	58.9 Å²	58.9	55%	0.546	35%	0.345	S	S	.	.			trans	57.7	64.4	174.6	0	0	0	0	0	115.1	G337	G335-G337 PolarHBondContact O-N 3.13Å
336	Y	92.9	Very high	92.3	Very high	161 Å²	161	52.9 Å²	52.9	63%	0.631	32%	0.322	S	S	*	.			trans	-58.7	-31	178.7	-67.6	-63.8	0	0	0	114.1	W325 I329 V334 D338	W325-Y336 HydrophobicContact CH2-CE2 4.16Å; W325-Y336 AromaticContact CZ2-CD2 3.91Å; W325-Y336 HydrophobicContact CZ2-CD2 3.91Å; W325-Y336 AromaticContact CZ2-CE2 3.92Å; W325-Y336 HydrophobicContact CZ2-CE2 3.92Å; I329-Y336 HydrophobicContact CD1-CD2 4.32Å; I329-Y336 HydrophobicContact CG2-CD2 4.03Å; I329-Y336 HydrophobicContact CG2-CE2 4.06Å; V334-Y336 HydrophobicContact CG1-CD1 4.06Å; V334-Y336 HydrophobicContact CG1-CD2 4.12Å; V334-Y336 HydrophobicContact CG1-CE1 3.7Å; V334-Y336 HydrophobicContact CG1-CE2 3.76Å; V334-Y336 HydrophobicContact CG1-CG 4.26Å; Y336-D338 VanDerWaalsContact C-N 3.34Å
337	G	89	Confident	92.2	Very high	63 Å²	63	58 Å²	58	65%	0.649	34%	0.344	S	S	*	.	S	Bend	trans	82	10.7	179.4	0	0	0	0	0	114.6	G335	G335-G337 PolarHBondContact O-N 3.13Å
338	D	89.7	Confident	92.1	Very high	94 Å²	94	59.9 Å²	59.9	50%	0.503	36%	0.364	S	S	.	.	S	Bend	trans	-64.4	-39.3	170.5	57.1	-32.3	0	0	0	112.2	W325 Y336	W325-D338 PolarHBondContact NE1-OD2 2.77Å; Y336-D338 VanDerWaalsContact C-N 3.34Å
339	V	89.3	Confident	91.9	Very high	26 Å²	26	60.3 Å²	60.3	16%	0.158	36%	0.364	C	S	.	.	S	Bend	trans	-130.7	139.8	174.8	-172.4	0	0	0	0	109.6	T317 T322 L326	T317-V339 HydrophobicContact CG2-CG1 3.7Å; T317-V339 WeakPolarHBondContact OG1-CG1 3.37Å; T322-V339 HydrophobicContact CG2-CB 4.26Å; T322-V339 HydrophobicContact CG2-CG1 3.75Å; T322-V339 HydrophobicContact CG2-CG2 3.81Å; L326-V339 WeakPolarHBondContact CD1-O 3.22Å; L326-V339 HydrophobicContact CD2-CG1 4.1Å
340	A	89.8	Confident	91.9	Very high	42 Å²	42	60.7 Å²	60.7	35%	0.347	37%	0.368	S	S	.	.			trans	-147.5	141.3	-179.5	0	0	0	0	0	111.9	K342	A340-K342 PolarHBondContact O-N 3.39Å
341	P	90.4	Very high	91.9	Very high	21 Å²	21	65.5 Å²	65.5	14%	0.136	39%	0.392	C	S	.	.			trans	-65.9	134	179.4	29.9	-35.8	0	0	0	110.7	L305 E309 K347 C350	L305-P341 HydrophobicContact CD1-CB 4.23Å; E309-P341 WeakPolarHBondContact OE1-CB 3.45Å; P341-K347 HydrophobicContact CB-CG 4.33Å; P341-K347 HydrophobicContact CG-CG 3.96Å; P341-C350 HydrophobicContact CG-CB 4.27Å
342	K	87.3	Confident	91.8	Very high	133 Å²	133	70.7 Å²	70.7	58%	0.578	41%	0.414	S	S	*	.			trans	-94.9	-33.9	177.8	-58.9	-57.6	-179.2	-177.8	0	111.1	E309 A340	E309-K342 PolarHBondContact OE1-N 2.96Å; E309-K342 VanDerWaalsContact OE1-N 3.15Å; E309-K342 PolarHBondContact OE2-N 3.21Å; A340-K342 PolarHBondContact O-N 3.39Å
343	T	87.1	Confident	91.8	Very high	35 Å²	35	66.2 Å²	66.2	22%	0.215	39%	0.391	C	S	.	.	S	Bend	trans	-76.7	151.6	-177.6	71.9	0	0	0	0	112.6	C308 E309 C345 G346 K347	C308-T343 WeakPolarHBondContact O-CG2 3.29Å; E309-T343 VanDerWaalsContact OE1-CB 3.3Å; E309-T343 WeakPolarHBondContact OE1-CB 3.29Å; E309-T343 PolarHBondContact OE1-N 3.36Å; E309-T343 PolarHBondContact OE1-OG1 3.48Å; T343-C345 VanDerWaalsContact C-N 3.27Å; T343-C345 PolarHBondContact O-N 2.96Å; T343-G346 PolarHBondContact O-N 2.9Å; T343-G346 PolarHBondContact OG1-N 3.43Å; T343-K347 WeakPolarHBondContact O-CG 3.35Å; T343-K347 PolarHBondContact O-N 2.84Å
344	S	88.3	Confident	91.8	Very high	107 Å²	107	62.7 Å²	62.7	75%	0.748	37%	0.373	S	S	*	.	H	α-helix	trans	-62.6	-35.5	174.4	-58.5	0	0	0	0	112	G348	S344-G348 PolarHBondContact O-N 3.43Å; S344-G348 VanDerWaalsContact O-N 3.16Å
345	C	87.3	Confident	91.9	Very high	54 Å²	54	63.1 Å²	63.1	37%	0.365	38%	0.375	S	S	.	.	H	α-helix	trans	-63.3	-51.8	173.6	172.9	0	0	0	0	111.5	C308 T343 K347 G348 V349	C308-C345 HydrophobicContact CB-CB 3.6Å; C308-C345 WeakPolarHBondContact CB-SG 3.34Å; C308-C345 WeakPolarHBondContact SG-CB 3.42Å; C308-C345 CovalentContact SG-SG 2.03Å; C308-C345 PolarHBondContact SG-SG 3.49Å; T343-C345 VanDerWaalsContact C-N 3.27Å; T343-C345 PolarHBondContact O-N 2.96Å; C345-K347 VanDerWaalsContact C-N 3.29Å; C345-K347 PolarHBondContact O-N 3.31Å; C345-G348 WeakPolarHBondContact O-CA 3.29Å; C345-G348 PolarHBondContact O-N 3.26Å; C345-V349 PolarHBondContact O-N 2.75Å
346	G	89.4	Confident	92	Very high	0 Å²	0	63 Å²	63	0%	0	36%	0.361	C	S	.	.	H	α-helix	trans	-59.2	-39.5	-179	0	0	0	0	0	112.5	T343 G348 V349 C350	T343-G346 PolarHBondContact O-N 2.9Å; T343-G346 PolarHBondContact OG1-N 3.43Å; G346-G348 VanDerWaalsContact C-N 3.32Å; G346-G348 PolarHBondContact O-N 2.96Å; G346-V349 PolarHBondContact O-N 3.48Å; G346-C350 PolarHBondContact O-N 2.86Å
347	K	92.6	Very high	92.2	Very high	115 Å²	115	55.3 Å²	55.3	50%	0.5	33%	0.331	S	S	.	.	H	α-helix	trans	-59.1	-41.3	171.7	-71.7	170.8	-176.6	171.1	0	112.3	P341 T343 C345 C350 L351	P341-K347 HydrophobicContact CB-CG 4.33Å; P341-K347 HydrophobicContact CG-CG 3.96Å; T343-K347 WeakPolarHBondContact O-CG 3.35Å; T343-K347 PolarHBondContact O-N 2.84Å; C345-K347 VanDerWaalsContact C-N 3.29Å; C345-K347 PolarHBondContact O-N 3.31Å; K347-C350 PolarHBondContact O-N 3.26Å; K347-L351 WeakPolarHBondContact O-CB 3.23Å; K347-L351 PolarHBondContact O-N 2.95Å
348	G	92.6	Very high	92.5	Very high	39 Å²	39	56.1 Å²	56.1	40%	0.402	32%	0.323	S	S	.	.	H	α-helix	trans	-62.2	-44.1	174.5	0	0	0	0	0	112.9	S344 C345 G346 L351 F352	S344-G348 PolarHBondContact O-N 3.43Å; S344-G348 VanDerWaalsContact O-N 3.16Å; C345-G348 WeakPolarHBondContact O-CA 3.29Å; C345-G348 PolarHBondContact O-N 3.26Å; G346-G348 VanDerWaalsContact C-N 3.32Å; G346-G348 PolarHBondContact O-N 2.96Å; G348-L351 PolarHBondContact O-N 2.9Å; G348-F352 PolarHBondContact O-N 3.19Å
349	V	93	Very high	92.8	Very high	22 Å²	22	54 Å²	54	13%	0.133	32%	0.319	C	S	.	.	H	α-helix	trans	-62.6	-45	176.4	177.1	0	0	0	0	111.2	M236 A301 M304 L305 I327 C345 G346 F352 T353	M236-V349 HydrophobicContact CE-CG2 4.49Å; A301-V349 HydrophobicContact CB-CG1 4.4Å; M304-V349 HydrophobicContact CB-CG1 4.45Å; M304-V349 HydrophobicContact CB-CG2 4.36Å; L305-V349 HydrophobicContact CB-CG1 4.32Å; I327-V349 HydrophobicContact CD1-CG1 4.19Å; C345-V349 PolarHBondContact O-N 2.75Å; G346-V349 PolarHBondContact O-N 3.48Å; V349-F352 PolarHBondContact O-N 2.98Å; V349-T353 VanDerWaalsContact O-CB 3.31Å; V349-T353 WeakPolarHBondContact O-CB 3.44Å; V349-T353 PolarHBondContact O-N 3.46Å; V349-T353 PolarHBondContact O-OG1 3.39Å
350	C	94.7	Very high	93	Very high	16 Å²	16	53.2 Å²	53.2	11%	0.108	31%	0.314	C	S	.	.	H	α-helix	trans	-64.5	-39.7	176.8	-73.3	0	0	0	0	112.4	T330 P341 G346 K347 T353 G354	T330-C350 HydrophobicContact CG2-CB 4.27Å; T330-C350 WeakPolarHBondContact CG2-O 3.44Å; P341-C350 HydrophobicContact CG-CB 4.27Å; G346-C350 PolarHBondContact O-N 2.86Å; K347-C350 PolarHBondContact O-N 3.26Å; C350-T353 WeakPolarHBondContact O-CB 3.44Å; C350-T353 PolarHBondContact O-N 3.31Å; C350-G354 PolarHBondContact O-N 3.14Å
351	L	96.4	Very high	93.3	Very high	129 Å²	129	54 Å²	54	68%	0.675	32%	0.315	S	S	*	.	H	α-helix	trans	-62.7	-46.1	175.9	-177.3	137.7	0	0	0	111.4	K347 G348 T353 G354 V355	K347-L351 WeakPolarHBondContact O-CB 3.23Å; K347-L351 PolarHBondContact O-N 2.95Å; G348-L351 PolarHBondContact O-N 2.9Å; L351-T353 VanDerWaalsContact C-N 3.32Å; L351-T353 PolarHBondContact O-N 2.92Å; L351-G354 PolarHBondContact O-N 3.41Å; L351-V355 WeakPolarHBondContact O-CG2 3.48Å; L351-V355 PolarHBondContact O-N 3.45Å; L351-V355 VanDerWaalsContact O-N 3.12Å
352	F	95.1	Very high	93.5	Very high	115 Å²	115	56 Å²	56	50%	0.504	33%	0.333	S	S	.	.	H	α-helix	trans	-62.2	-41	175.6	-175.5	-104.7	0	0	0	112	F297 G348 V349 G354 V355 M356	F297-F352 HydrophobicContact CE2-CD1 4.02Å; F297-F352 AromaticContact CE2-CE1 3.76Å; F297-F352 HydrophobicContact CE2-CE1 3.76Å; F297-F352 HydrophobicContact CZ-CD1 4.08Å; F297-F352 HydrophobicContact CZ-CE1 4.22Å; G348-F352 PolarHBondContact O-N 3.19Å; V349-F352 PolarHBondContact O-N 2.98Å; F352-G354 PolarHBondContact O-N 3.43Å; F352-V355 PolarHBondContact O-N 2.98Å; F352-M356 HydrophobicContact CD1-CG 4.24Å; F352-M356 HydrophobicContact CE1-CG 3.81Å; F352-M356 HydrophobicContact CE2-CG 4.25Å; F352-M356 HydrophobicContact CZ-CG 3.81Å; F352-M356 HydrophobicContact CZ-SD 4.25Å; F352-M356 WeakPolarHBondContact O-CG 3.25Å; F352-M356 PolarHBondContact O-N 3.01Å
353	T	96.5	Very high	93.7	Very high	0 Å²	0	52.9 Å²	52.9	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-59.4	-44.2	175.6	-62.9	0	0	0	0	112	F297 I327 T330 F331 V349 C350 L351 M356 G357	F297-T353 HydrophobicContact CE1-CG2 4.02Å; I327-T353 HydrophobicContact CD1-CG2 4.08Å; I327-T353 HydrophobicContact CG2-CG2 4.04Å; T330-T353 HydrophobicContact CG2-CG2 4.02Å; F331-T353 HydrophobicContact CB-CG2 3.91Å; F331-T353 HydrophobicContact CD2-CG2 4.38Å; V349-T353 VanDerWaalsContact O-CB 3.31Å; V349-T353 WeakPolarHBondContact O-CB 3.44Å; V349-T353 PolarHBondContact O-N 3.46Å; V349-T353 PolarHBondContact O-OG1 3.39Å; C350-T353 WeakPolarHBondContact O-CB 3.44Å; C350-T353 PolarHBondContact O-N 3.31Å; L351-T353 VanDerWaalsContact C-N 3.32Å; L351-T353 PolarHBondContact O-N 2.92Å; T353-M356 PolarHBondContact O-N 3.32Å; T353-G357 PolarHBondContact O-N 3.24Å
354	G	97.1	Very high	94	Very high	17 Å²	17	55 Å²	55	18%	0.175	33%	0.331	C	S	.	.	H	α-helix	trans	-63.7	-45.1	176.8	0	0	0	0	0	112.8	C350 L351 F352 M356 G357 V358	C350-G354 PolarHBondContact O-N 3.14Å; L351-G354 PolarHBondContact O-N 3.41Å; F352-G354 PolarHBondContact O-N 3.43Å; G354-M356 PolarHBondContact O-N 2.66Å; G354-G357 PolarHBondContact O-N 3.16Å; G354-V358 WeakPolarHBondContact O-CG2 3.42Å; G354-V358 PolarHBondContact O-N 2.03Å
355	V	97.3	Very high	94.2	Very high	84 Å²	84	54.4 Å²	54.4	51%	0.509	32%	0.322	S	S	.	.	H	α-helix	trans	-62.2	-42.9	177.4	176.4	0	0	0	0	111.3	L351 F352 V358 A359	L351-V355 WeakPolarHBondContact O-CG2 3.48Å; L351-V355 PolarHBondContact O-N 3.45Å; L351-V355 VanDerWaalsContact O-N 3.12Å; F352-V355 PolarHBondContact O-N 2.98Å; V355-V358 PolarHBondContact O-N 2.98Å; V355-A359 PolarHBondContact O-N 2.73Å
356	M	95.9	Very high	94.5	Very high	49 Å²	49	54.8 Å²	54.8	24%	0.241	33%	0.33	C	S	.	.	H	α-helix	trans	-66.4	-37	175	-71.3	-58	87.6	0	0	113.1	F297 F331 F352 T353 G354 A359 C360	F297-M356 HydrophobicContact CE1-CB 4.23Å; F297-M356 HydrophobicContact CE2-CG 4.45Å; F297-M356 HydrophobicContact CZ-CB 4.08Å; F297-M356 HydrophobicContact CZ-CG 4.3Å; F331-M356 HydrophobicContact CE2-CB 4.33Å; F352-M356 HydrophobicContact CD1-CG 4.24Å; F352-M356 HydrophobicContact CE1-CG 3.81Å; F352-M356 HydrophobicContact CE2-CG 4.25Å; F352-M356 HydrophobicContact CZ-CG 3.81Å; F352-M356 HydrophobicContact CZ-SD 4.25Å; F352-M356 WeakPolarHBondContact O-CG 3.25Å; F352-M356 PolarHBondContact O-N 3.01Å; T353-M356 PolarHBondContact O-N 3.32Å; G354-M356 PolarHBondContact O-N 2.66Å; M356-A359 HydrophobicContact CE-CB 4.2Å; M356-A359 PolarHBondContact O-N 3.15Å; M356-C360 WeakPolarHBondContact O-CB 3.37Å; M356-C360 PolarHBondContact O-N 2.72Å; M356-C360 PolarHBondContact O-SG 2.56Å; M356-C360 VanDerWaalsContact O-SG 3.38Å
357	G	96.6	Very high	94.6	Very high	0 Å²	0	56 Å²	56	0%	0	34%	0.336	C	S	.	.	H	α-helix	trans	-54.9	-53.4	171.6	0	0	0	0	0	112.4	F331 T353 G354 A359 C360 T361	F331-G357 WeakPolarHBondContact O-CA 3.39Å; T353-G357 PolarHBondContact O-N 3.24Å; G354-G357 PolarHBondContact O-N 3.16Å; G357-A359 VanDerWaalsContact C-N 3.35Å; G357-A359 PolarHBondContact O-N 3.04Å; G357-C360 PolarHBondContact O-N 2.94Å; G357-T361 WeakPolarHBondContact O-CG2 3.3Å; G357-T361 PolarHBondContact O-N 3Å; G357-T361 PolarHBondContact O-OG1 3.33Å
358	V	97	Very high	94.6	Very high	81 Å²	81	53.7 Å²	53.7	49%	0.491	33%	0.331	S	S	.	.	H	α-helix	trans	-61.6	-40.7	178.5	176.5	0	0	0	0	112.1	T333 G354 V355 C360 T361 A362	T333-V358 HydrophobicContact CG2-CG2 3.89Å; G354-V358 WeakPolarHBondContact O-CG2 3.42Å; G354-V358 PolarHBondContact O-N 2.03Å; V355-V358 PolarHBondContact O-N 2.98Å; V358-C360 VanDerWaalsContact C-N 3.35Å; V358-C360 PolarHBondContact O-N 2.91Å; V358-T361 WeakPolarHBondContact CA-OG1 3.47Å; V358-T361 PolarHBondContact O-N 2.88Å; V358-T361 PolarHBondContact O-OG1 3.01Å; V358-A362 WeakPolarHBondContact O-CB 3.27Å; V358-A362 PolarHBondContact O-N 3.47Å
359	A	95.2	Very high	94.6	Very high	50 Å²	50	56.1 Å²	56.1	41%	0.413	34%	0.338	S	S	.	.	H	α-helix	trans	-63.5	-41.2	176.2	0	0	0	0	0	112	V355 M356 G357 M363	V355-A359 PolarHBondContact O-N 2.73Å; M356-A359 HydrophobicContact CE-CB 4.2Å; M356-A359 PolarHBondContact O-N 3.15Å; G357-A359 VanDerWaalsContact C-N 3.35Å; G357-A359 PolarHBondContact O-N 3.04Å; A359-M363 PolarHBondContact O-N 3.32Å; A359-M363 VanDerWaalsContact O-N 3.12Å
360	C	94.1	Very high	94.5	Very high	9 Å²	9	60.9 Å²	60.9	6%	0.061	36%	0.359	C	S	.	.	H	α-helix	trans	-69.2	-39.4	177.5	-75.7	0	0	0	0	113	F293 F331 M356 G357 V358 M363 L364	F293-C360 VanDerWaalsContact CE1-SG 3.5Å; F331-C360 HydrophobicContact CE1-CB 4.24Å; F331-C360 HydrophobicContact CE2-CB 4.49Å; F331-C360 HydrophobicContact CZ-CB 3.62Å; M356-C360 WeakPolarHBondContact O-CB 3.37Å; M356-C360 PolarHBondContact O-N 2.72Å; M356-C360 PolarHBondContact O-SG 2.56Å; M356-C360 VanDerWaalsContact O-SG 3.38Å; G357-C360 PolarHBondContact O-N 2.94Å; V358-C360 VanDerWaalsContact C-N 3.35Å; V358-C360 PolarHBondContact O-N 2.91Å; C360-M363 PolarHBondContact O-N 2.96Å; C360-L364 WeakPolarHBondContact O-CB 3.31Å; C360-L364 PolarHBondContact O-N 3.02Å
361	T	95	Very high	94.2	Very high	59 Å²	59	66 Å²	66	36%	0.362	38%	0.38	S	S	.	.	H	α-helix	trans	-65.1	-41.9	176.2	55.9	0	0	0	0	111.2	G357 V358 M363 L364 V365	G357-T361 WeakPolarHBondContact O-CG2 3.3Å; G357-T361 PolarHBondContact O-N 3Å; G357-T361 PolarHBondContact O-OG1 3.33Å; V358-T361 WeakPolarHBondContact CA-OG1 3.47Å; V358-T361 PolarHBondContact O-N 2.88Å; V358-T361 PolarHBondContact O-OG1 3.01Å; T361-M363 VanDerWaalsContact C-N 3.34Å; T361-M363 PolarHBondContact O-N 2.98Å; T361-L364 WeakPolarHBondContact O-CB 3.41Å; T361-L364 PolarHBondContact O-N 3.16Å; T361-V365 WeakPolarHBondContact O-CG2 3.36Å; T361-V365 PolarHBondContact O-N 2.93Å
362	A	95.3	Very high	94	Very high	61 Å²	61	66.4 Å²	66.4	50%	0.504	38%	0.381	S	S	.	.	H	α-helix	trans	-59.5	-43.8	174.5	0	0	0	0	0	112.3	V358 V365 A366	V358-A362 WeakPolarHBondContact O-CB 3.27Å; V358-A362 PolarHBondContact O-N 3.47Å; A362-V365 PolarHBondContact O-N 3.23Å; A362-A366 PolarHBondContact O-N 3.35Å
363	M	91.3	Very high	93.8	Very high	69 Å²	69	63.6 Å²	63.6	34%	0.34	38%	0.38	S	S	.	.	H	α-helix	trans	-63.9	-41.3	175.8	-176.3	167.8	70.5	0	0	112.1	M282 L290 A359 C360 T361 A366 I367	M282-M363 HydrophobicContact SD-CE 4.08Å; M282-M363 HydrophobicContact SD-SD 4.04Å; L290-M363 HydrophobicContact CD1-CE 3.71Å; L290-M363 HydrophobicContact CG-CE 4.26Å; A359-M363 PolarHBondContact O-N 3.32Å; A359-M363 VanDerWaalsContact O-N 3.12Å; C360-M363 PolarHBondContact O-N 2.96Å; T361-M363 VanDerWaalsContact C-N 3.34Å; T361-M363 PolarHBondContact O-N 2.98Å; M363-A366 PolarHBondContact O-N 3.1Å; M363-I367 HydrophobicContact CG-CD1 3.94Å; M363-I367 WeakPolarHBondContact O-CD1 3.3Å; M363-I367 WeakPolarHBondContact O-CG1 3.42Å; M363-I367 PolarHBondContact O-N 3.13Å; M363-I367 VanDerWaalsContact O-N 3.08Å
364	L	92.4	Very high	93.5	Very high	79 Å²	79	67.5 Å²	67.5	41%	0.414	40%	0.4	S	S	.	.	H	α-helix	trans	-61.7	-44.2	176.8	-179.1	63.9	0	0	0	111.7	L290 C360 T361 A366 I367 V368	L290-L364 HydrophobicContact CD1-CB 4.17Å; L290-L364 HydrophobicContact CD1-CD1 4.35Å; C360-L364 WeakPolarHBondContact O-CB 3.31Å; C360-L364 PolarHBondContact O-N 3.02Å; T361-L364 WeakPolarHBondContact O-CB 3.41Å; T361-L364 PolarHBondContact O-N 3.16Å; L364-A366 VanDerWaalsContact C-N 3.33Å; L364-A366 PolarHBondContact O-N 3.42Å; L364-I367 PolarHBondContact O-N 3.35Å; L364-V368 HydrophobicContact CD1-CG2 4.06Å; L364-V368 HydrophobicContact CG-CG2 4.29Å; L364-V368 WeakPolarHBondContact O-CB 3.3Å; L364-V368 VanDerWaalsContact O-CG2 3.3Å; L364-V368 WeakPolarHBondContact O-CG2 3.3Å; L364-V368 PolarHBondContact O-N 3.34Å
365	V	94.2	Very high	93.3	Very high	94 Å²	94	71.9 Å²	71.9	57%	0.57	42%	0.42	S	S	*	.	H	α-helix	trans	-60.4	-42.4	177.2	171.4	0	0	0	0	111.3	T361 A362 V368 T369	T361-V365 WeakPolarHBondContact O-CG2 3.36Å; T361-V365 PolarHBondContact O-N 2.93Å; A362-V365 PolarHBondContact O-N 3.23Å; V365-V368 PolarHBondContact O-N 2.97Å; V365-T369 WeakPolarHBondContact O-CB 3.24Å; V365-T369 PolarHBondContact O-N 3.27Å; V365-T369 PolarHBondContact O-OG1 3.32Å
366	A	93	Very high	92.8	Very high	63 Å²	63	73.8 Å²	73.8	52%	0.521	42%	0.421	S	S	.	.	H	α-helix	trans	-61.6	-46.5	176.9	0	0	0	0	0	111.7	A362 M363 L364 T369 E370	A362-A366 PolarHBondContact O-N 3.35Å; M363-A366 PolarHBondContact O-N 3.1Å; L364-A366 VanDerWaalsContact C-N 3.33Å; L364-A366 PolarHBondContact O-N 3.42Å; A366-T369 PolarHBondContact O-N 2.84Å; A366-E370 PolarHBondContact O-N 3.36Å; A366-E370 VanDerWaalsContact O-N 3.1Å
367	I	91.4	Very high	92.5	Very high	26 Å²	26	73.5 Å²	73.5	13%	0.133	43%	0.431	C	S	.	.	H	α-helix	trans	-62	-48.2	178	-72	163.7	0	0	0	111.4	P286 L290 M363 L364 T369 E370 K371	P286-I367 HydrophobicContact CB-CB 4.36Å; P286-I367 HydrophobicContact CB-CD1 3.71Å; P286-I367 HydrophobicContact CB-CG1 4.01Å; P286-I367 HydrophobicContact CB-CG2 3.43Å; P286-I367 VanDerWaalsContact CB-CG2 3.43Å; P286-I367 HydrophobicContact CG-CG2 3.81Å; L290-I367 HydrophobicContact CD1-CD1 4.29Å; M363-I367 HydrophobicContact CG-CD1 3.94Å; M363-I367 WeakPolarHBondContact O-CD1 3.3Å; M363-I367 WeakPolarHBondContact O-CG1 3.42Å; M363-I367 PolarHBondContact O-N 3.13Å; M363-I367 VanDerWaalsContact O-N 3.08Å; L364-I367 PolarHBondContact O-N 3.35Å; I367-T369 VanDerWaalsContact C-N 3.29Å; I367-T369 PolarHBondContact O-N 3.06Å; I367-E370 PolarHBondContact O-N 3.47Å; I367-K371 HydrophobicContact CG2-CG 4.44Å; I367-K371 WeakPolarHBondContact O-CG 3.22Å; I367-K371 PolarHBondContact O-N 3.47Å
368	V	92	Very high	92.3	Very high	66 Å²	66	78.7 Å²	78.7	40%	0.4	46%	0.455	S	S	.	.	H	α-helix	trans	-62.9	-41.1	-178.4	168.6	0	0	0	0	110	L364 V365 E370 K371 L372	L364-V368 HydrophobicContact CD1-CG2 4.06Å; L364-V368 HydrophobicContact CG-CG2 4.29Å; L364-V368 WeakPolarHBondContact O-CB 3.3Å; L364-V368 VanDerWaalsContact O-CG2 3.3Å; L364-V368 WeakPolarHBondContact O-CG2 3.3Å; L364-V368 PolarHBondContact O-N 3.34Å; V365-V368 PolarHBondContact O-N 2.97Å; V368-E370 PolarHBondContact O-N 3.41Å; V368-K371 PolarHBondContact O-N 3.11Å; V368-L372 HydrophobicContact CG1-CD1 3.55Å; V368-L372 HydrophobicContact CG1-CG 4.1Å; V368-L372 WeakPolarHBondContact O-CB 3.48Å; V368-L372 VanDerWaalsContact O-CG 3.24Å; V368-L372 WeakPolarHBondContact O-CG 3.31Å; V368-L372 PolarHBondContact O-N 3.07Å
369	T	93.6	Very high	92	Very high	90 Å²	90	78.9 Å²	78.9	55%	0.552	45%	0.449	S	S	*	.	H	α-helix	trans	-60.6	-44.5	177.2	-58.7	0	0	0	0	111.8	V365 A366 I367 A373	V365-T369 WeakPolarHBondContact O-CB 3.24Å; V365-T369 PolarHBondContact O-N 3.27Å; V365-T369 PolarHBondContact O-OG1 3.32Å; A366-T369 PolarHBondContact O-N 2.84Å; I367-T369 VanDerWaalsContact C-N 3.29Å; I367-T369 PolarHBondContact O-N 3.06Å; T369-A373 PolarHBondContact O-N 3.38Å; T369-A373 VanDerWaalsContact O-N 3.14Å
370	E	89.5	Confident	91.7	Very high	121 Å²	121	81.1 Å²	81.1	57%	0.565	45%	0.451	S	S	*	.	H	α-helix	trans	-67.6	-39.3	177.7	-172.2	178.3	175.9	0	0	112.2	A366 I367 V368 A373	A366-E370 PolarHBondContact O-N 3.36Å; A366-E370 VanDerWaalsContact O-N 3.1Å; I367-E370 PolarHBondContact O-N 3.47Å; V368-E370 PolarHBondContact O-N 3.41Å; E370-A373 WeakPolarHBondContact O-CB 3.35Å; E370-A373 PolarHBondContact O-N 3.45Å
371	K	88.6	Confident	91.6	Very high	125 Å²	125	85.1 Å²	85.1	54%	0.543	48%	0.475	S	S	.	.	H	α-helix	trans	-74.4	-27.7	179	-66.8	-58.9	-179	-164.3	0	113.9	I367 V368 A373	I367-K371 HydrophobicContact CG2-CG 4.44Å; I367-K371 WeakPolarHBondContact O-CG 3.22Å; I367-K371 PolarHBondContact O-N 3.47Å; V368-K371 PolarHBondContact O-N 3.11Å; K371-A373 VanDerWaalsContact C-N 3.33Å
372	L	92.1	Very high	91.5	Very high	136 Å²	136	87 Å²	87	71%	0.712	48%	0.479	S	S	*	.	H	α-helix	trans	-81.6	-14.5	173.1	-69.1	176.3	0	0	0	112.6	V368 L374	V368-L372 HydrophobicContact CG1-CD1 3.55Å; V368-L372 HydrophobicContact CG1-CG 4.1Å; V368-L372 WeakPolarHBondContact O-CB 3.48Å; V368-L372 VanDerWaalsContact O-CG 3.24Å; V368-L372 WeakPolarHBondContact O-CG 3.31Å; V368-L372 PolarHBondContact O-N 3.07Å; L372-L374 PolarHBondContact O-N 2.88Å
373	A	91.7	Very high	91.3	Very high	57 Å²	57	86 Å²	86	47%	0.471	46%	0.464	S	S	.	.	S	Bend	trans	-67.8	120.7	175.8	0	0	0	0	0	110.1	T369 E370 K371 N375	T369-A373 PolarHBondContact O-N 3.38Å; T369-A373 VanDerWaalsContact O-N 3.14Å; E370-A373 WeakPolarHBondContact O-CB 3.35Å; E370-A373 PolarHBondContact O-N 3.45Å; K371-A373 VanDerWaalsContact C-N 3.33Å; A373-N375 PolarHBondContact O-N 2.94Å
374	L	91	Very high	91.3	Very high	81 Å²	81	88.6 Å²	88.6	42%	0.424	47%	0.473	S	S	.	.	P	Polyproline II helix	trans	-57	136.2	176.5	-65.8	173.6	0	0	0	111	L372 E378 K379	L372-L374 PolarHBondContact O-N 2.88Å; L374-E378 HydrophobicContact CB-CB 4.26Å; L374-E378 HydrophobicContact CD2-CB 4.23Å; L374-K379 HydrophobicContact CB-CD 4.34Å; L374-K379 HydrophobicContact CB-CG 3.52Å; L374-K379 HydrophobicContact CD1-CG 4.29Å; L374-K379 WeakPolarHBondContact O-CE 3.3Å; L374-K379 PolarHBondContact O-NZ 3.47Å
375	N	91.4	Very high	91.4	Very high	109 Å²	109	89.5 Å²	89.5	58%	0.583	48%	0.476	S	S	*	.	P	Polyproline II helix	trans	-63.2	158.8	173.8	-170.2	6.1	0	0	0	110.5	A373 G377 E378 K379	A373-N375 PolarHBondContact O-N 2.94Å; N375-G377 PolarHBondContact O-N 3.1Å; N375-E378 HydrophobicContact CB-CB 4.42Å; N375-E378 HydrophobicContact CB-CG 4.13Å; N375-E378 PolarHBondContact N-OE2 2.81Å; N375-E378 PolarHBondContact O-N 3.45Å; N375-E378 VanDerWaalsContact O-N 3.14Å; N375-K379 WeakPolarHBondContact O-CB 3.32Å; N375-K379 WeakPolarHBondContact O-CG 3.27Å; N375-K379 PolarHBondContact O-N 3.14Å
376	K	87.6	Confident	91.4	Very high	125 Å²	125	87.2 Å²	87.2	54%	0.543	46%	0.46	S	S	.	.	H	α-helix	trans	-53.9	-40.5	177.9	-173	177.8	179.6	179.2	0	112	H380 M452	K376-H380 WeakPolarHBondContact O-CB 3.45Å; K376-H380 PolarHBondContact O-N 3.34Å; K376-H380 VanDerWaalsContact O-N 3.07Å; K376-M452 HydrophobicContact CG-CE 4.29Å
377	G	89.3	Confident	91.4	Very high	43 Å²	43	86.8 Å²	86.8	44%	0.443	45%	0.449	S	S	.	.	H	α-helix	trans	-67	-47.2	175.9	0	0	0	0	0	113.2	N375 K379 H380 V381	N375-G377 PolarHBondContact O-N 3.1Å; G377-K379 VanDerWaalsContact C-N 3.34Å; G377-K379 PolarHBondContact O-N 3.03Å; G377-H380 WeakPolarHBondContact O-CB 3.24Å; G377-H380 PolarHBondContact O-N 3.47Å; G377-H380 VanDerWaalsContact O-N 3.14Å; G377-V381 WeakPolarHBondContact O-CG2 3.37Å; G377-V381 PolarHBondContact O-N 3.2Å
378	E	91.8	Very high	91.5	Very high	108 Å²	108	88.4 Å²	88.4	51%	0.505	46%	0.457	S	S	.	.	H	α-helix	trans	-62.2	-41.4	177.5	-65	170.8	159.4	0	0	111.6	L374 N375 H380 V381 H382	L374-E378 HydrophobicContact CB-CB 4.26Å; L374-E378 HydrophobicContact CD2-CB 4.23Å; N375-E378 HydrophobicContact CB-CB 4.42Å; N375-E378 HydrophobicContact CB-CG 4.13Å; N375-E378 PolarHBondContact N-OE2 2.81Å; N375-E378 PolarHBondContact O-N 3.45Å; N375-E378 VanDerWaalsContact O-N 3.14Å; E378-H380 VanDerWaalsContact C-N 3.33Å; E378-H380 PolarHBondContact O-N 3.07Å; E378-V381 PolarHBondContact O-N 3.43Å; E378-H382 VanDerWaalsContact O-CB 3.28Å; E378-H382 WeakPolarHBondContact O-CB 3.33Å; E378-H382 PolarHBondContact O-N 2.98Å
379	K	91.1	Very high	91.7	Very high	86 Å²	86	89.8 Å²	89.8	37%	0.374	46%	0.46	S	S	.	.	H	α-helix	trans	-58.5	-44.5	172.8	-74.5	177.4	174	163.9	0	111.5	L374 N375 G377 H382 F383 M452	L374-K379 HydrophobicContact CB-CD 4.34Å; L374-K379 HydrophobicContact CB-CG 3.52Å; L374-K379 HydrophobicContact CD1-CG 4.29Å; L374-K379 WeakPolarHBondContact O-CE 3.3Å; L374-K379 PolarHBondContact O-NZ 3.47Å; N375-K379 WeakPolarHBondContact O-CB 3.32Å; N375-K379 WeakPolarHBondContact O-CG 3.27Å; N375-K379 PolarHBondContact O-N 3.14Å; G377-K379 VanDerWaalsContact C-N 3.34Å; G377-K379 PolarHBondContact O-N 3.03Å; K379-H382 PolarHBondContact O-N 2.91Å; K379-F383 HydrophobicContact CB-CE2 4.46Å; K379-F383 WeakPolarHBondContact O-CD2 3.29Å; K379-F383 WeakPolarHBondContact O-CG 3.43Å; K379-F383 PolarHBondContact O-N 3.22Å; K379-M452 HydrophobicContact CB-CE 3.92Å; K379-M452 HydrophobicContact CB-SD 4.21Å
380	H	88.7	Confident	91.8	Very high	97 Å²	97	85.9 Å²	85.9	45%	0.449	44%	0.435	S	S	.	.	H	α-helix	trans	-61.7	-48.2	178.7	-175.9	71.8	0	0	0	111.4	K376 G377 E378 H382 F383 F384 M452	K376-H380 WeakPolarHBondContact O-CB 3.45Å; K376-H380 PolarHBondContact O-N 3.34Å; K376-H380 VanDerWaalsContact O-N 3.07Å; G377-H380 WeakPolarHBondContact O-CB 3.24Å; G377-H380 PolarHBondContact O-N 3.47Å; G377-H380 VanDerWaalsContact O-N 3.14Å; E378-H380 VanDerWaalsContact C-N 3.33Å; E378-H380 PolarHBondContact O-N 3.07Å; H380-H382 PolarHBondContact O-N 2.85Å; H380-F383 PolarHBondContact O-N 3.3Å; H380-F384 WeakPolarHBondContact O-CB 3.26Å; H380-F384 PolarHBondContact O-N 2.97Å; H380-M452 HydrophobicContact CB-CE 4.18Å
381	V	93.1	Very high	92.1	Very high	93 Å²	93	81.3 Å²	81.3	56%	0.564	42%	0.417	S	S	*	.	H	α-helix	trans	-62	-43.1	176.8	176.1	0	0	0	0	111.3	G377 E378 F384 M385	G377-V381 WeakPolarHBondContact O-CG2 3.37Å; G377-V381 PolarHBondContact O-N 3.2Å; E378-V381 PolarHBondContact O-N 3.43Å; V381-F384 PolarHBondContact O-N 2.91Å; V381-M385 WeakPolarHBondContact O-CB 3.45Å; V381-M385 PolarHBondContact O-N 3.33Å
382	H	92.1	Very high	92.5	Very high	97 Å²	97	80.7 Å²	80.7	45%	0.449	41%	0.414	S	S	.	.	H	α-helix	trans	-61.2	-46.7	178.2	174.9	-94.7	0	0	0	112.1	E378 K379 H380 M385 M386	E378-H382 VanDerWaalsContact O-CB 3.28Å; E378-H382 WeakPolarHBondContact O-CB 3.33Å; E378-H382 PolarHBondContact O-N 2.98Å; K379-H382 PolarHBondContact O-N 2.91Å; H380-H382 PolarHBondContact O-N 2.85Å; H382-M385 PolarHBondContact O-N 2.96Å; H382-M386 WeakPolarHBondContact O-CB 3.46Å; H382-M386 PolarHBondContact O-N 3.24Å
383	F	91.7	Very high	92.7	Very high	41 Å²	41	81.7 Å²	81.7	18%	0.18	41%	0.408	C	S	.	.	H	α-helix	trans	-67.5	-39	178.2	-72.2	-45.4	0	0	0	112.6	K379 H380 M386 D387 L445 V449 M452	K379-F383 HydrophobicContact CB-CE2 4.46Å; K379-F383 WeakPolarHBondContact O-CD2 3.29Å; K379-F383 WeakPolarHBondContact O-CG 3.43Å; K379-F383 PolarHBondContact O-N 3.22Å; H380-F383 PolarHBondContact O-N 3.3Å; F383-M386 HydrophobicContact CD1-CE 3.6Å; F383-M386 HydrophobicContact CE1-CE 3.98Å; F383-M386 PolarHBondContact O-N 2.86Å; F383-D387 PolarHBondContact O-N 3.43Å; F383-L445 HydrophobicContact CB-CD1 4.06Å; F383-L445 HydrophobicContact CD1-CD1 3.37Å; F383-L445 HydrophobicContact CE1-CD1 4.05Å; F383-L445 HydrophobicContact CG-CD1 3.99Å; F383-V449 HydrophobicContact CB-CG2 3.82Å; F383-V449 HydrophobicContact CG-CG2 4.35Å; F383-M452 HydrophobicContact CD2-SD 3.59Å; F383-M452 VanDerWaalsContact CD2-SD 3.59Å; F383-M452 HydrophobicContact CE2-SD 3.56Å; F383-M452 VanDerWaalsContact CE2-SD 3.56Å
384	F	91.9	Very high	93	Very high	123 Å²	123	80 Å²	80	54%	0.539	39%	0.391	S	S	.	.	H	α-helix	trans	-60.4	-46.8	174.4	-178.5	-104	0	0	0	111.8	H380 V381 M386 D387 I388	H380-F384 WeakPolarHBondContact O-CB 3.26Å; H380-F384 PolarHBondContact O-N 2.97Å; V381-F384 PolarHBondContact O-N 2.91Å; F384-M386 VanDerWaalsContact C-N 3.32Å; F384-M386 PolarHBondContact O-N 3.47Å; F384-D387 PolarHBondContact O-N 3.41Å; F384-I388 HydrophobicContact CD1-CD1 3.92Å; F384-I388 HydrophobicContact CE1-CD1 3.4Å; F384-I388 VanDerWaalsContact CE1-CD1 3.4Å; F384-I388 HydrophobicContact CE1-CG1 4.45Å; F384-I388 HydrophobicContact CE2-CD1 4.47Å; F384-I388 HydrophobicContact CZ-CD1 3.72Å; F384-I388 HydrophobicContact CZ-CG1 4.47Å; F384-I388 PolarHBondContact O-N 2.9Å; F384-I388 VanDerWaalsContact O-N 3.15Å
385	M	93.9	Very high	93.3	Very high	98 Å²	98	83.6 Å²	83.6	48%	0.483	40%	0.399	S	S	.	.	H	α-helix	trans	-59.4	-43.7	175.8	-175.2	61.7	66.3	0	0	111.5	V381 H382 D387 I388 Q389	V381-M385 WeakPolarHBondContact O-CB 3.45Å; V381-M385 PolarHBondContact O-N 3.33Å; H382-M385 PolarHBondContact O-N 2.96Å; M385-D387 PolarHBondContact O-N 2.83Å; M385-I388 PolarHBondContact O-N 3.48Å; M385-Q389 WeakPolarHBondContact O-CG 3.32Å; M385-Q389 PolarHBondContact O-N 3.46Å; M385-Q389 VanDerWaalsContact O-N 3.1Å
386	M	93.8	Very high	93.6	Very high	46 Å²	46	84.8 Å²	84.8	23%	0.227	40%	0.401	C	S	.	.	H	α-helix	trans	-65.3	-36.4	178.6	-173.1	171.1	40.2	0	0	112.3	H382 F383 F384 Q389 I390 L445	H382-M386 WeakPolarHBondContact O-CB 3.46Å; H382-M386 PolarHBondContact O-N 3.24Å; F383-M386 HydrophobicContact CD1-CE 3.6Å; F383-M386 HydrophobicContact CE1-CE 3.98Å; F383-M386 PolarHBondContact O-N 2.86Å; F384-M386 VanDerWaalsContact C-N 3.32Å; F384-M386 PolarHBondContact O-N 3.47Å; M386-Q389 PolarHBondContact O-N 3.1Å; M386-I390 HydrophobicContact CG-CD1 3.82Å; M386-I390 HydrophobicContact CG-CG1 4.29Å; M386-I390 WeakPolarHBondContact O-CB 3.46Å; M386-I390 VanDerWaalsContact O-CG1 3.3Å; M386-I390 WeakPolarHBondContact O-CG1 3.4Å; M386-I390 PolarHBondContact O-N 3.17Å; M386-I390 HydrophobicContact SD-CD1 4.41Å; M386-L445 HydrophobicContact CB-CD2 4.01Å; M386-L445 HydrophobicContact CE-CD1 3.35Å; M386-L445 HydrophobicContact CE-CD2 3.98Å; M386-L445 HydrophobicContact CE-CG 4.23Å; M386-L445 HydrophobicContact CG-CD2 3.87Å
387	D	93	Very high	94	Very high	55 Å²	55	79.1 Å²	79.1	29%	0.294	38%	0.377	S	S	.	.	H	α-helix	trans	-65.6	-42.4	177.2	-175.7	52.9	0	0	0	111.9	F383 F384 M385 Q389 I390 S391 L445	F383-D387 PolarHBondContact O-N 3.43Å; F384-D387 PolarHBondContact O-N 3.41Å; M385-D387 PolarHBondContact O-N 2.83Å; D387-Q389 VanDerWaalsContact C-N 3.33Å; D387-Q389 PolarHBondContact O-N 3.25Å; D387-I390 PolarHBondContact O-N 2.9Å; D387-S391 VanDerWaalsContact O-CB 3.25Å; D387-S391 WeakPolarHBondContact O-CB 3.4Å; D387-S391 PolarHBondContact O-N 3.32Å; D387-S391 PolarHBondContact O-OG 3.08Å; D387-L445 HydrophobicContact CB-CD2 3.81Å
388	I	94.5	Very high	94.4	Very high	59 Å²	59	78.6 Å²	78.6	30%	0.303	37%	0.369	S	S	.	.	H	α-helix	trans	-59.3	-46.4	174.1	-67.2	172.5	0	0	0	110.6	F384 M385 S391 K392	F384-I388 HydrophobicContact CD1-CD1 3.92Å; F384-I388 HydrophobicContact CE1-CD1 3.4Å; F384-I388 VanDerWaalsContact CE1-CD1 3.4Å; F384-I388 HydrophobicContact CE1-CG1 4.45Å; F384-I388 HydrophobicContact CE2-CD1 4.47Å; F384-I388 HydrophobicContact CZ-CD1 3.72Å; F384-I388 HydrophobicContact CZ-CG1 4.47Å; F384-I388 PolarHBondContact O-N 2.9Å; F384-I388 VanDerWaalsContact O-N 3.15Å; M385-I388 PolarHBondContact O-N 3.48Å; I388-S391 PolarHBondContact O-N 3.42Å; I388-K392 HydrophobicContact CG2-CD 4.46Å; I388-K392 WeakPolarHBondContact O-CG 3.49Å; I388-K392 PolarHBondContact O-N 3.42Å
389	Q	96.4	Very high	94.7	Very high	96 Å²	96	76 Å²	76	45%	0.449	37%	0.365	S	S	.	.	H	α-helix	trans	-65.2	-43.8	-179.6	-71.2	-177.6	10	0	0	112.3	M385 M386 D387 K392 R393	M385-Q389 WeakPolarHBondContact O-CG 3.32Å; M385-Q389 PolarHBondContact O-N 3.46Å; M385-Q389 VanDerWaalsContact O-N 3.1Å; M386-Q389 PolarHBondContact O-N 3.1Å; D387-Q389 VanDerWaalsContact C-N 3.33Å; D387-Q389 PolarHBondContact O-N 3.25Å; Q389-K392 PolarHBondContact O-N 3.45Å; Q389-R393 WeakPolarHBondContact O-CG 3.32Å; Q389-R393 PolarHBondContact O-N 3.46Å
390	I	95.4	Very high	95	Very high	8 Å²	8	75.8 Å²	75.8	4%	0.041	37%	0.369	C	S	.	.	H	α-helix	trans	-63.7	-44.1	177	-70.8	172.4	0	0	0	110.2	M386 D387 K392 R393 I394 K441 Q442 L445	M386-I390 HydrophobicContact CG-CD1 3.82Å; M386-I390 HydrophobicContact CG-CG1 4.29Å; M386-I390 WeakPolarHBondContact O-CB 3.46Å; M386-I390 VanDerWaalsContact O-CG1 3.3Å; M386-I390 WeakPolarHBondContact O-CG1 3.4Å; M386-I390 PolarHBondContact O-N 3.17Å; M386-I390 HydrophobicContact SD-CD1 4.41Å; D387-I390 PolarHBondContact O-N 2.9Å; I390-K392 VanDerWaalsContact C-N 3.31Å; I390-K392 PolarHBondContact O-N 2.82Å; I390-R393 PolarHBondContact O-N 3.01Å; I390-R393 VanDerWaalsContact O-N 3.1Å; I390-I394 HydrophobicContact CG2-CD1 3.72Å; I390-I394 HydrophobicContact CG2-CG1 4.21Å; I390-I394 WeakPolarHBondContact O-CG1 3.3Å; I390-I394 PolarHBondContact O-N 3.02Å; I390-K441 HydrophobicContact CD1-CD 4.06Å; I390-K441 HydrophobicContact CD1-CG 3.94Å; I390-Q442 HydrophobicContact CG2-CB 3.71Å; I390-Q442 HydrophobicContact CG2-CG 4.11Å; I390-L445 HydrophobicContact CD1-CD2 3.83Å
391	S	94.9	Very high	95.4	Very high	25 Å²	25	72.6 Å²	72.6	18%	0.175	36%	0.356	C	S	.	.	H	α-helix	trans	-58.7	-41.3	177.1	-67.7	0	0	0	0	112.1	D387 I388 I394 R395 Q442	D387-S391 VanDerWaalsContact O-CB 3.25Å; D387-S391 WeakPolarHBondContact O-CB 3.4Å; D387-S391 PolarHBondContact O-N 3.32Å; D387-S391 PolarHBondContact O-OG 3.08Å; I388-S391 PolarHBondContact O-N 3.42Å; S391-I394 PolarHBondContact O-N 3.36Å; S391-R395 WeakPolarHBondContact O-CG 3.22Å; S391-R395 PolarHBondContact O-N 3.47Å; S391-Q442 PolarHBondContact OG-NE2 3.41Å
392	K	97.3	Very high	95.6	Very high	111 Å²	111	74 Å²	74	48%	0.483	36%	0.36	S	S	.	.	H	α-helix	trans	-60.4	-49.3	172	-74.2	176.5	179.9	-177.1	0	111.7	I388 Q389 I390 I394 R395 H396	I388-K392 HydrophobicContact CG2-CD 4.46Å; I388-K392 WeakPolarHBondContact O-CG 3.49Å; I388-K392 PolarHBondContact O-N 3.42Å; Q389-K392 PolarHBondContact O-N 3.45Å; I390-K392 VanDerWaalsContact C-N 3.31Å; I390-K392 PolarHBondContact O-N 2.82Å; K392-I394 VanDerWaalsContact C-N 3.32Å; K392-I394 PolarHBondContact O-N 3.38Å; K392-R395 PolarHBondContact O-N 2.81Å; K392-H396 PolarHBondContact O-CD2 2.94Å; K392-H396 PolarHBondContact O-N 3.27Å; K392-H396 VanDerWaalsContact O-N 3.16Å
393	R	97	Very high	95.8	Very high	157 Å²	157	76.9 Å²	76.9	59%	0.592	37%	0.366	S	S	*	.	H	α-helix	trans	-62.9	-36.2	179.5	-68.5	-174.2	-169.4	-150.7	4.4	112.7	Q389 I390 H396 A397 L438	Q389-R393 WeakPolarHBondContact O-CG 3.32Å; Q389-R393 PolarHBondContact O-N 3.46Å; I390-R393 PolarHBondContact O-N 3.01Å; I390-R393 VanDerWaalsContact O-N 3.1Å; R393-H396 PolarHBondContact O-N 3.36Å; R393-A397 WeakPolarHBondContact O-CB 3.41Å; R393-A397 PolarHBondContact O-N 3.45Å; R393-L438 HydrophobicContact CB-CD1 3.98Å; R393-L438 HydrophobicContact CB-CD2 4.21Å
394	I	97.1	Very high	95.9	Very high	22 Å²	22	76.2 Å²	76.2	11%	0.113	36%	0.364	C	S	.	.	H	α-helix	trans	-62.7	-43.2	175.5	-73	173.3	0	0	0	110.7	I390 S391 K392 A397 A398 F435 L438 Q442	I390-I394 HydrophobicContact CG2-CD1 3.72Å; I390-I394 HydrophobicContact CG2-CG1 4.21Å; I390-I394 WeakPolarHBondContact O-CG1 3.3Å; I390-I394 PolarHBondContact O-N 3.02Å; S391-I394 PolarHBondContact O-N 3.36Å; K392-I394 VanDerWaalsContact C-N 3.32Å; K392-I394 PolarHBondContact O-N 3.38Å; I394-A397 PolarHBondContact O-N 3.13Å; I394-A398 VanDerWaalsContact O-CB 3.3Å; I394-A398 WeakPolarHBondContact O-CB 3.4Å; I394-A398 PolarHBondContact O-N 3.07Å; I394-F435 HydrophobicContact CG2-CD2 4.37Å; I394-F435 HydrophobicContact CG2-CE2 3.8Å; I394-L438 HydrophobicContact CD1-CB 4.47Å; I394-L438 HydrophobicContact CG1-CB 3.71Å; I394-Q442 HydrophobicContact CD1-CB 3.87Å; I394-Q442 HydrophobicContact CD1-CG 4.25Å
395	R	97.1	Very high	96	Very high	157 Å²	157	73.5 Å²	73.5	59%	0.592	36%	0.36	S	S	*	.	H	α-helix	trans	-60.9	-44.9	176	-70.8	-172.9	-68.8	-116.1	5	112	S391 K392 A398 A399	S391-R395 WeakPolarHBondContact O-CG 3.22Å; S391-R395 PolarHBondContact O-N 3.47Å; K392-R395 PolarHBondContact O-N 2.81Å; R395-A398 PolarHBondContact O-N 3.28Å; R395-A399 PolarHBondContact O-N 3.37Å
396	H	97.4	Very high	96	Very high	133 Å²	133	75.8 Å²	75.8	62%	0.616	36%	0.363	S	S	*	.	H	α-helix	trans	-64.4	-44	175.7	-69.8	-65.9	0	0	0	112.7	K392 R393 A398 A399 N400	K392-H396 PolarHBondContact O-CD2 2.94Å; K392-H396 PolarHBondContact O-N 3.27Å; K392-H396 VanDerWaalsContact O-N 3.16Å; R393-H396 PolarHBondContact O-N 3.36Å; H396-A398 VanDerWaalsContact C-N 3.33Å; H396-A398 PolarHBondContact O-N 3.39Å; H396-A399 WeakPolarHBondContact O-CB 3.46Å; H396-A399 PolarHBondContact O-N 2.95Å; H396-N400 PolarHBondContact O-N 3.03Å
397	A	97.5	Very high	95.9	Very high	7 Å²	7	75.4 Å²	75.4	6%	0.058	36%	0.362	C	S	.	.	H	α-helix	trans	-63.9	-39.3	177.3	0	0	0	0	0	111.9	R393 I394 N400 V401 V434 F435 L438	R393-A397 WeakPolarHBondContact O-CB 3.41Å; R393-A397 PolarHBondContact O-N 3.45Å; I394-A397 PolarHBondContact O-N 3.13Å; A397-N400 PolarHBondContact O-N 2.93Å; A397-V401 WeakPolarHBondContact O-CG2 3.32Å; A397-V401 PolarHBondContact O-N 3.35Å; A397-V434 HydrophobicContact CB-CG1 4.36Å; A397-F435 HydrophobicContact CB-CB 4.23Å; A397-F435 HydrophobicContact CB-CD2 4.31Å; A397-L438 HydrophobicContact CB-CD1 3.75Å
398	A	97.8	Very high	95.7	Very high	31 Å²	31	74.5 Å²	74.5	26%	0.256	36%	0.357	S	S	.	.	H	α-helix	trans	-61.9	-43.8	174	0	0	0	0	0	111.6	I394 R395 H396 N400 V401 L402 F435	I394-A398 VanDerWaalsContact O-CB 3.3Å; I394-A398 WeakPolarHBondContact O-CB 3.4Å; I394-A398 PolarHBondContact O-N 3.07Å; R395-A398 PolarHBondContact O-N 3.28Å; H396-A398 VanDerWaalsContact C-N 3.33Å; H396-A398 PolarHBondContact O-N 3.39Å; A398-N400 VanDerWaalsContact C-N 3.31Å; A398-N400 PolarHBondContact O-N 2.88Å; A398-V401 PolarHBondContact O-N 3.28Å; A398-L402 WeakPolarHBondContact O-CG 3.26Å; A398-L402 PolarHBondContact O-N 3.43Å; A398-F435 HydrophobicContact CB-CD2 4.13Å; A398-F435 HydrophobicContact CB-CE2 3.89Å
399	A	97.9	Very high	95.4	Very high	53 Å²	53	79.3 Å²	79.3	44%	0.438	38%	0.377	S	S	.	.	H	α-helix	trans	-59.9	-40.6	175.1	0	0	0	0	0	112	R395 H396 L402 R403	R395-A399 PolarHBondContact O-N 3.37Å; H396-A399 WeakPolarHBondContact O-CB 3.46Å; H396-A399 PolarHBondContact O-N 2.95Å; A399-L402 PolarHBondContact O-N 3.21Å; A399-R403 WeakPolarHBondContact O-CB 3.01Å; A399-R403 PolarHBondContact O-N 3.2Å
400	N	96.9	Very high	95	Very high	83 Å²	83	83 Å²	83	44%	0.444	39%	0.387	S	S	.	.	H	α-helix	trans	-65.8	-40.4	175.4	-72.4	-14.6	0	0	0	112.6	H396 A397 A398 L402 R403 E404 A431	H396-N400 PolarHBondContact O-N 3.03Å; A397-N400 PolarHBondContact O-N 2.93Å; A398-N400 VanDerWaalsContact C-N 3.31Å; A398-N400 PolarHBondContact O-N 2.88Å; N400-L402 VanDerWaalsContact C-N 3.34Å; N400-L402 PolarHBondContact O-N 2.99Å; N400-R403 PolarHBondContact O-N 3.24Å; N400-E404 WeakPolarHBondContact O-CG 3.25Å; N400-E404 PolarHBondContact O-N 3.19Å; N400-A431 HydrophobicContact CB-CB 4.47Å
401	V	97.5	Very high	94.3	Very high	29 Å²	29	83.6 Å²	83.6	18%	0.176	39%	0.393	C	S	.	.	H	α-helix	trans	-60	-46.2	174	171.9	0	0	0	0	110.6	A397 A398 C405 L428 A431 I432 F435	A397-V401 WeakPolarHBondContact O-CG2 3.32Å; A397-V401 PolarHBondContact O-N 3.35Å; A398-V401 PolarHBondContact O-N 3.28Å; V401-C405 WeakPolarHBondContact O-CB 3.42Å; V401-C405 PolarHBondContact O-N 3.03Å; V401-L428 HydrophobicContact CG1-CD1 4.12Å; V401-L428 WeakPolarHBondContact O-CD1 3.43Å; V401-A431 VanDerWaalsContact CG2-C 3.47Å; V401-A431 HydrophobicContact CG2-CB 3.71Å; V401-A431 WeakPolarHBondContact CG2-O 3.47Å; V401-I432 HydrophobicContact CG1-CG1 4.02Å; V401-I432 HydrophobicContact CG2-CG1 4.18Å; V401-F435 HydrophobicContact CG2-CB 4.06Å
402	L	97.1	Very high	92.9	Very high	124 Å²	124	85 Å²	85	65%	0.649	40%	0.403	S	S	*	.	H	α-helix	trans	-62.9	-43.9	177.7	-68.7	174.1	0	0	0	111.8	A398 A399 N400 C405 W406	A398-L402 WeakPolarHBondContact O-CG 3.26Å; A398-L402 PolarHBondContact O-N 3.43Å; A399-L402 PolarHBondContact O-N 3.21Å; N400-L402 VanDerWaalsContact C-N 3.34Å; N400-L402 PolarHBondContact O-N 2.99Å; L402-C405 PolarHBondContact O-N 3.15Å; L402-W406 WeakPolarHBondContact O-CB 3.24Å; L402-W406 PolarHBondContact O-N 3.3Å
403	R	95.9	Very high	91.3	Very high	156 Å²	156	85 Å²	85	59%	0.589	41%	0.414	S	S	*	.	H	α-helix	trans	-58.5	-53.2	176.6	176.7	-175.9	169.9	-179.3	-0.8	111.7	A399 N400 C405 W406 L407	A399-R403 WeakPolarHBondContact O-CB 3.01Å; A399-R403 PolarHBondContact O-N 3.2Å; N400-R403 PolarHBondContact O-N 3.24Å; R403-C405 VanDerWaalsContact C-N 3.32Å; R403-C405 PolarHBondContact O-N 3.35Å; R403-W406 PolarHBondContact O-N 3.02Å; R403-L407 HydrophobicContact CG-CD1 3.96Å; R403-L407 WeakPolarHBondContact O-CG 3.32Å; R403-L407 PolarHBondContact O-N 3.28Å
404	E	94.1	Very high	89.6	Confident	27 Å²	27	81.9 Å²	81.9	13%	0.126	42%	0.422	C	S	.	.	H	α-helix	trans	-68	-33.3	-179	-66.4	-54.6	141.4	0	0	112.1	N400 L407 L408 H424 C427 L428	N400-E404 WeakPolarHBondContact O-CG 3.25Å; N400-E404 PolarHBondContact O-N 3.19Å; E404-L407 PolarHBondContact O-N 2.88Å; E404-L408 VanDerWaalsContact O-CB 3.23Å; E404-L408 WeakPolarHBondContact O-CB 3.47Å; E404-L408 PolarHBondContact O-N 3.27Å; E404-H424 IonicContact OE2-CE1 3.95Å; E404-H424 IonicContact OE2-CG 3.96Å; E404-H424 IonicContact OE2-ND1 2.99Å; E404-H424 PolarHBondContact OE2-ND1 2.94Å; E404-C427 HydrophobicContact CG-CB 3.92Å; E404-C427 WeakPolarHBondContact OE2-CB 3.31Å; E404-L428 HydrophobicContact CB-CB 3.92Å; E404-L428 HydrophobicContact CB-CD1 4.08Å
405	C	94.4	Very high	87.9	Confident	67 Å²	67	90.5 Å²	90.5	45%	0.453	46%	0.459	S	S	.	.	H	α-helix	trans	-63.6	-43.7	174	-174.2	0	0	0	0	111.3	V401 L402 R403 H409 L428	V401-C405 WeakPolarHBondContact O-CB 3.42Å; V401-C405 PolarHBondContact O-N 3.03Å; L402-C405 PolarHBondContact O-N 3.15Å; R403-C405 VanDerWaalsContact C-N 3.32Å; R403-C405 PolarHBondContact O-N 3.35Å; C405-H409 WeakPolarHBondContact O-CB 3.47Å; C405-H409 PolarHBondContact O-N 2.59Å; C405-L428 HydrophobicContact CB-CD1 4.02Å; C405-L428 HydrophobicContact CB-CD2 4.49Å
406	W	93.8	Very high	86.2	Confident	146 Å²	146	84.8 Å²	84.8	55%	0.553	45%	0.448	S	S	*	.	H	α-helix	trans	-66.6	-44.5	175.9	-179.7	83.5	0	0	0	112.3	L402 R403 L408 H409 R410	L402-W406 WeakPolarHBondContact O-CB 3.24Å; L402-W406 PolarHBondContact O-N 3.3Å; R403-W406 PolarHBondContact O-N 3.02Å; W406-L408 VanDerWaalsContact C-N 3.33Å; W406-L408 PolarHBondContact O-N 3.08Å; W406-H409 PolarHBondContact O-N 3.47Å; W406-R410 WeakPolarHBondContact O-CB 3.45Å; W406-R410 PolarHBondContact O-N 2.9Å
407	L	90.8	Very high	85	Confident	38 Å²	38	81.3 Å²	81.3	20%	0.199	44%	0.439	C	S	.	.	H	α-helix	trans	-61.6	-41	177	-71.4	171.9	0	0	0	111.8	R403 E404 R410 A411	R403-L407 HydrophobicContact CG-CD1 3.96Å; R403-L407 WeakPolarHBondContact O-CG 3.32Å; R403-L407 PolarHBondContact O-N 3.28Å; E404-L407 PolarHBondContact O-N 2.88Å; L407-R410 PolarHBondContact O-N 3.21Å; L407-A411 VanDerWaalsContact O-CB 3.29Å; L407-A411 WeakPolarHBondContact O-CB 3.2Å; L407-A411 PolarHBondContact O-N 3Å
408	L	89.8	Confident	84.1	Confident	35 Å²	35	89.8 Å²	89.8	18%	0.183	47%	0.47	C	S	.	.	H	α-helix	trans	-63.4	-42.3	174.8	-177.5	64.1	0	0	0	112.1	E404 W406 A411 H421 H424 Q425 L428	E404-L408 VanDerWaalsContact O-CB 3.23Å; E404-L408 WeakPolarHBondContact O-CB 3.47Å; E404-L408 PolarHBondContact O-N 3.27Å; W406-L408 VanDerWaalsContact C-N 3.33Å; W406-L408 PolarHBondContact O-N 3.08Å; L408-A411 PolarHBondContact O-N 2.99Å; L408-H421 VanDerWaalsContact CD1-CE1 3.48Å; L408-H421 WeakPolarHBondContact CD1-CE1 3.34Å; L408-H424 HydrophobicContact CB-CB 4.23Å; L408-H424 HydrophobicContact CD1-CB 4.15Å; L408-Q425 HydrophobicContact CD1-CB 4.13Å; L408-L428 HydrophobicContact CD2-CD2 3.62Å
409	H	88.1	Confident	83.2	Confident	160 Å²	160	92.7 Å²	92.7	74%	0.741	48%	0.481	S	S	*	.	H	α-helix	trans	-65.7	-41.7	177	-177.7	73	0	0	0	112	C405 W406 A411	C405-H409 WeakPolarHBondContact O-CB 3.47Å; C405-H409 PolarHBondContact O-N 2.59Å; W406-H409 PolarHBondContact O-N 3.47Å; H409-A411 VanDerWaalsContact C-N 3.34Å
410	R	87.4	Confident	82.5	Confident	175 Å²	175	95.3 Å²	95.3	66%	0.66	48%	0.484	S	S	*	.	H	α-helix	trans	-66.5	-35.3	176.5	-179.1	179.2	169	-176.2	-1.8	112.2	W406 L407 S412	W406-R410 WeakPolarHBondContact O-CB 3.45Å; W406-R410 PolarHBondContact O-N 2.9Å; L407-R410 PolarHBondContact O-N 3.21Å; R410-S412 PolarHBondContact O-N 3.5Å
411	A	79.9	Confident	81.9	Confident	20 Å²	20	94 Å²	94	17%	0.165	48%	0.475	C	S	.	.	S	Bend	trans	-71.8	70.7	174.2	0	0	0	0	0	110.4	L407 L408 H409 H421	L407-A411 VanDerWaalsContact O-CB 3.29Å; L407-A411 WeakPolarHBondContact O-CB 3.2Å; L407-A411 PolarHBondContact O-N 3Å; L408-A411 PolarHBondContact O-N 2.99Å; H409-A411 VanDerWaalsContact C-N 3.34Å; A411-H421 PolarHBondContact O-ND1 2.85Å
412	S	66.3	Low	81.5	Confident	53 Å²	53	98.9 Å²	98.9	37%	0.371	49%	0.49	S	S	.	.			trans	-60.2	132.4	-179.7	176	0	0	0	0	110.8	R410 A414 K415 G416	R410-S412 PolarHBondContact O-N 3.5Å; S412-A414 PolarHBondContact O-N 2.97Å; S412-A414 PolarHBondContact OG-N 2.93Å; S412-K415 PolarHBondContact O-N 3.36Å; S412-G416 PolarHBondContact O-N 3.4Å
413	P	63.7	Low	81.1	Confident	112 Å²	112	100.3 Å²	100.3	73%	0.727	49%	0.487	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.8	-14	179.2	25.6	-33.9	0	0	0	113.4
414	A	62	Low	80.7	Confident	91 Å²	91	95.3 Å²	95.3	75%	0.752	47%	0.47	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.8	-14	-178.7	0	0	0	0	0	114.7	S412	S412-A414 PolarHBondContact O-N 2.97Å; S412-A414 PolarHBondContact OG-N 2.93Å
415	K	60.4	Low	80.5	Confident	204 Å²	204	98.4 Å²	98.4	89%	0.887	49%	0.485	S	S	*	.	T	Hydrogen-bonded Turn	trans	-131.7	-16.2	-174.1	-94.4	-178.3	175.7	178.9	0	115.6	S412	S412-K415 PolarHBondContact O-N 3.36Å
416	G	62.5	Low	80.5	Confident	36 Å²	36	102.8 Å²	102.8	37%	0.371	49%	0.492	S	S	.	.	S	Bend	trans	-108.5	164.5	-177.6	0	0	0	0	0	114.4	S412 R418	S412-G416 PolarHBondContact O-N 3.4Å; G416-R418 PolarHBondContact O-N 3.49Å
417	S	70.9	Confident	80.5	Confident	61 Å²	61	98.3 Å²	98.3	43%	0.427	48%	0.482	S	S	.	.			trans	-61.8	129	174.2	170.7	0	0	0	0	110.5	D419 E420 H421	S417-D419 PolarHBondContact O-N 3.44Å; S417-D419 PolarHBondContact OG-N 3.34Å; S417-E420 WeakPolarHBondContact O-CB 3.2Å; S417-E420 PolarHBondContact O-N 2.95Å; S417-H421 PolarHBondContact O-N 3.34Å
418	R	78.1	Confident	80.8	Confident	184 Å²	184	97.6 Å²	97.6	69%	0.694	48%	0.478	S	S	*	.	H	α-helix	trans	-54.5	-27.1	177.8	-69.5	177.3	71.6	-175.4	4.5	112.5	G416 R422	G416-R418 PolarHBondContact O-N 3.49Å; R418-R422 WeakPolarHBondContact O-CG 3.07Å; R418-R422 PolarHBondContact O-N 2.89Å
419	D	80.1	Confident	81.1	Confident	92 Å²	92	99.9 Å²	99.9	49%	0.492	49%	0.491	S	S	.	.	H	α-helix	trans	-75.2	-32.3	178.6	-69.4	-26.3	0	0	0	113	S417 R422 R423	S417-D419 PolarHBondContact O-N 3.44Å; S417-D419 PolarHBondContact OG-N 3.34Å; D419-R422 PolarHBondContact O-N 3.49Å; D419-R423 VanDerWaalsContact O-CG 3.25Å; D419-R423 WeakPolarHBondContact O-CG 3.46Å; D419-R423 PolarHBondContact O-N 3.39Å
420	E	82.6	Confident	81.5	Confident	108 Å²	108	98.2 Å²	98.2	51%	0.505	48%	0.483	S	S	.	.	H	α-helix	trans	-68.2	-42.6	174.2	-67.9	175.8	163.5	0	0	110.8	S417 R422 R423 H424	S417-E420 WeakPolarHBondContact O-CB 3.2Å; S417-E420 PolarHBondContact O-N 2.95Å; E420-R422 PolarHBondContact O-N 2.89Å; E420-R423 PolarHBondContact O-N 3.14Å; E420-R423 VanDerWaalsContact O-N 3.17Å; E420-H424 PolarHBondContact O-CD2 3.17Å; E420-H424 PolarHBondContact O-N 3.42Å
421	H	85.1	Confident	82	Confident	56 Å²	56	90.6 Å²	90.6	26%	0.259	46%	0.457	S	S	.	.	H	α-helix	trans	-59.9	-45.2	175.1	-166.8	86.8	0	0	0	111.4	L408 A411 S417 R423 H424 Q425	L408-H421 VanDerWaalsContact CD1-CE1 3.48Å; L408-H421 WeakPolarHBondContact CD1-CE1 3.34Å; A411-H421 PolarHBondContact O-ND1 2.85Å; S417-H421 PolarHBondContact O-N 3.34Å; H421-R423 VanDerWaalsContact C-N 3.34Å; H421-R423 PolarHBondContact O-N 3.23Å; H421-H424 PolarHBondContact O-N 3.2Å; H421-Q425 WeakPolarHBondContact O-CB 3.35Å; H421-Q425 PolarHBondContact O-N 3.43Å
422	R	87.8	Confident	82.8	Confident	131 Å²	131	92 Å²	92	49%	0.494	46%	0.462	S	S	.	.	H	α-helix	trans	-65.5	-31.4	175.5	-74	172.2	172.9	178.2	-4.5	113.5	R418 D419 E420 R426	R418-R422 WeakPolarHBondContact O-CG 3.07Å; R418-R422 PolarHBondContact O-N 2.89Å; D419-R422 PolarHBondContact O-N 3.49Å; E420-R422 PolarHBondContact O-N 2.89Å; R422-R426 WeakPolarHBondContact O-CG 3.47Å; R422-R426 PolarHBondContact O-N 2.94Å; R422-R426 PolarHBondContact O-NE 2.88Å
423	R	88.6	Confident	84.2	Confident	155 Å²	155	98 Å²	98	59%	0.585	48%	0.476	S	S	*	.	H	α-helix	trans	-68.1	-52.8	174.6	-76.4	171.9	-168	-100.2	4.8	110.6	D419 E420 H421 Q425 R426 C427	D419-R423 VanDerWaalsContact O-CG 3.25Å; D419-R423 WeakPolarHBondContact O-CG 3.46Å; D419-R423 PolarHBondContact O-N 3.39Å; E420-R423 PolarHBondContact O-N 3.14Å; E420-R423 VanDerWaalsContact O-N 3.17Å; H421-R423 VanDerWaalsContact C-N 3.34Å; H421-R423 PolarHBondContact O-N 3.23Å; R423-Q425 VanDerWaalsContact C-N 3.3Å; R423-Q425 PolarHBondContact O-N 3.44Å; R423-R426 WeakPolarHBondContact O-CB 3.17Å; R423-R426 PolarHBondContact O-N 3.28Å; R423-R426 VanDerWaalsContact O-N 3.08Å; R423-C427 PolarHBondContact O-N 3.36Å; R423-C427 PolarHBondContact O-SG 2.91Å; R423-C427 VanDerWaalsContact O-SG 3.32Å
424	H	88.8	Confident	85.8	Confident	50 Å²	50	96.2 Å²	96.2	23%	0.231	46%	0.463	C	S	.	.	H	α-helix	trans	-61.9	-36.1	178.2	-73.7	-57.7	0	0	0	112.9	E404 L408 E420 H421 R426 C427 L428	E404-H424 IonicContact OE2-CE1 3.95Å; E404-H424 IonicContact OE2-CG 3.96Å; E404-H424 IonicContact OE2-ND1 2.99Å; E404-H424 PolarHBondContact OE2-ND1 2.94Å; L408-H424 HydrophobicContact CB-CB 4.23Å; L408-H424 HydrophobicContact CD1-CB 4.15Å; E420-H424 PolarHBondContact O-CD2 3.17Å; E420-H424 PolarHBondContact O-N 3.42Å; H421-H424 PolarHBondContact O-N 3.2Å; H424-R426 PolarHBondContact O-N 3.06Å; H424-C427 PolarHBondContact O-N 3.45Å; H424-L428 VanDerWaalsContact O-CB 3.28Å; H424-L428 WeakPolarHBondContact O-CB 3.49Å; H424-L428 PolarHBondContact O-N 2.91Å
425	Q	90.2	Very high	87.5	Confident	93 Å²	93	94.3 Å²	94.3	44%	0.435	44%	0.438	S	S	.	.	H	α-helix	trans	-62.3	-41.5	173.8	-172.4	-179.5	-4.5	0	0	112.1	L408 H421 R423 L429	L408-Q425 HydrophobicContact CD1-CB 4.13Å; H421-Q425 WeakPolarHBondContact O-CB 3.35Å; H421-Q425 PolarHBondContact O-N 3.43Å; R423-Q425 VanDerWaalsContact C-N 3.3Å; R423-Q425 PolarHBondContact O-N 3.44Å; Q425-L429 WeakPolarHBondContact O-CG 3.31Å; Q425-L429 PolarHBondContact O-N 2.85Å
426	R	93.9	Very high	89.3	Confident	159 Å²	159	92.8 Å²	92.8	60%	0.6	43%	0.426	S	S	*	.	H	α-helix	trans	-65.5	-47	175	-77	-174.9	-72.9	165.3	-5.5	111.6	R422 R423 H424 L428 L429 E430	R422-R426 WeakPolarHBondContact O-CG 3.47Å; R422-R426 PolarHBondContact O-N 2.94Å; R422-R426 PolarHBondContact O-NE 2.88Å; R423-R426 WeakPolarHBondContact O-CB 3.17Å; R423-R426 PolarHBondContact O-N 3.28Å; R423-R426 VanDerWaalsContact O-N 3.08Å; H424-R426 PolarHBondContact O-N 3.06Å; R426-L428 VanDerWaalsContact C-N 3.3Å; R426-L428 PolarHBondContact O-N 3.43Å; R426-L429 PolarHBondContact O-N 2.85Å; R426-E430 WeakPolarHBondContact O-CB 3.31Å; R426-E430 PolarHBondContact O-N 3.05Å
427	C	94.5	Very high	90.9	Very high	52 Å²	52	96.9 Å²	96.9	35%	0.351	44%	0.436	S	S	.	.	H	α-helix	trans	-60	-40	177.1	-63.9	0	0	0	0	112	E404 R423 H424 E430 A431	E404-C427 HydrophobicContact CG-CB 3.92Å; E404-C427 WeakPolarHBondContact OE2-CB 3.31Å; R423-C427 PolarHBondContact O-N 3.36Å; R423-C427 PolarHBondContact O-SG 2.91Å; R423-C427 VanDerWaalsContact O-SG 3.32Å; H424-C427 PolarHBondContact O-N 3.45Å; C427-E430 PolarHBondContact O-N 3.48Å; C427-A431 WeakPolarHBondContact O-CB 3.48Å; C427-A431 PolarHBondContact O-N 2.95Å
428	L	96	Very high	92.1	Very high	22 Å²	22	95 Å²	95	12%	0.115	42%	0.421	C	S	.	.	H	α-helix	trans	-64.4	-47.6	175.8	178.3	59.7	0	0	0	111.9	V401 E404 C405 L408 H424 R426 E430 A431 I432	V401-L428 HydrophobicContact CG1-CD1 4.12Å; V401-L428 WeakPolarHBondContact O-CD1 3.43Å; E404-L428 HydrophobicContact CB-CB 3.92Å; E404-L428 HydrophobicContact CB-CD1 4.08Å; C405-L428 HydrophobicContact CB-CD1 4.02Å; C405-L428 HydrophobicContact CB-CD2 4.49Å; L408-L428 HydrophobicContact CD2-CD2 3.62Å; H424-L428 VanDerWaalsContact O-CB 3.28Å; H424-L428 WeakPolarHBondContact O-CB 3.49Å; H424-L428 PolarHBondContact O-N 2.91Å; R426-L428 VanDerWaalsContact C-N 3.3Å; R426-L428 PolarHBondContact O-N 3.43Å; L428-E430 VanDerWaalsContact C-N 3.27Å; L428-E430 PolarHBondContact O-N 3.43Å; L428-A431 PolarHBondContact O-N 3.23Å; L428-I432 HydrophobicContact CD1-CD1 3.93Å; L428-I432 HydrophobicContact CD1-CG1 4.16Å; L428-I432 HydrophobicContact CG-CD1 3.86Å; L428-I432 HydrophobicContact CG-CG1 4.48Å; L428-I432 WeakPolarHBondContact O-CB 3.47Å; L428-I432 VanDerWaalsContact O-CG1 3.25Å; L428-I432 WeakPolarHBondContact O-CG1 3.3Å; L428-I432 PolarHBondContact O-N 3.23Å
429	L	96.4	Very high	92.9	Very high	84 Å²	84	92.5 Å²	92.5	44%	0.44	41%	0.411	S	S	.	.	H	α-helix	trans	-61.3	-38.8	177.7	-72.7	173.2	0	0	0	111.5	Q425 R426 R433	Q425-L429 WeakPolarHBondContact O-CG 3.31Å; Q425-L429 PolarHBondContact O-N 2.85Å; R426-L429 PolarHBondContact O-N 2.85Å; L429-R433 VanDerWaalsContact O-CG 3.3Å; L429-R433 WeakPolarHBondContact O-CG 3.47Å; L429-R433 PolarHBondContact O-N 2.96Å
430	E	96.5	Very high	93.7	Very high	125 Å²	125	92.4 Å²	92.4	58%	0.584	41%	0.41	S	S	*	.	H	α-helix	trans	-65	-47.8	174.5	-172.6	171.2	-174.8	0	0	111.8	R426 C427 L428 I432 R433 V434	R426-E430 WeakPolarHBondContact O-CB 3.31Å; R426-E430 PolarHBondContact O-N 3.05Å; C427-E430 PolarHBondContact O-N 3.48Å; L428-E430 VanDerWaalsContact C-N 3.27Å; L428-E430 PolarHBondContact O-N 3.43Å; E430-I432 VanDerWaalsContact C-N 3.31Å; E430-I432 PolarHBondContact O-N 3.08Å; E430-R433 WeakPolarHBondContact O-CB 3.36Å; E430-R433 PolarHBondContact O-N 3.45Å; E430-R433 VanDerWaalsContact O-N 3.12Å; E430-V434 WeakPolarHBondContact O-CG2 3.37Å; E430-V434 PolarHBondContact O-N 3.38Å
431	A	96.8	Very high	94.2	Very high	14 Å²	14	92.2 Å²	92.2	12%	0.116	41%	0.408	C	S	.	.	H	α-helix	trans	-58.6	-41.4	175.9	0	0	0	0	0	112	N400 V401 C427 L428 V434 F435	N400-A431 HydrophobicContact CB-CB 4.47Å; V401-A431 VanDerWaalsContact CG2-C 3.47Å; V401-A431 HydrophobicContact CG2-CB 3.71Å; V401-A431 WeakPolarHBondContact CG2-O 3.47Å; C427-A431 WeakPolarHBondContact O-CB 3.48Å; C427-A431 PolarHBondContact O-N 2.95Å; L428-A431 PolarHBondContact O-N 3.23Å; A431-V434 PolarHBondContact O-N 3.38Å; A431-F435 WeakPolarHBondContact O-CB 3.29Å; A431-F435 PolarHBondContact O-N 2.97Å
432	I	97.1	Very high	94.6	Very high	50 Å²	50	91.5 Å²	91.5	26%	0.256	41%	0.405	S	S	.	.	H	α-helix	trans	-64.1	-42.6	175.6	-69.5	167.4	0	0	0	110.9	V401 L428 E430 F435 R436	V401-I432 HydrophobicContact CG1-CG1 4.02Å; V401-I432 HydrophobicContact CG2-CG1 4.18Å; L428-I432 HydrophobicContact CD1-CD1 3.93Å; L428-I432 HydrophobicContact CD1-CG1 4.16Å; L428-I432 HydrophobicContact CG-CD1 3.86Å; L428-I432 HydrophobicContact CG-CG1 4.48Å; L428-I432 WeakPolarHBondContact O-CB 3.47Å; L428-I432 VanDerWaalsContact O-CG1 3.25Å; L428-I432 WeakPolarHBondContact O-CG1 3.3Å; L428-I432 PolarHBondContact O-N 3.23Å; E430-I432 VanDerWaalsContact C-N 3.31Å; E430-I432 PolarHBondContact O-N 3.08Å; I432-F435 PolarHBondContact O-N 3.14Å; I432-R436 HydrophobicContact CG2-CG 4.34Å; I432-R436 WeakPolarHBondContact O-CB 3.26Å; I432-R436 VanDerWaalsContact O-CG 3.31Å; I432-R436 WeakPolarHBondContact O-CG 3.38Å; I432-R436 PolarHBondContact O-N 3.01Å
433	R	97.1	Very high	94.9	Very high	180 Å²	180	90.7 Å²	90.7	68%	0.679	40%	0.401	S	S	*	.	H	α-helix	trans	-61	-47.6	176.1	-75.3	175.3	-166.7	176.4	3.8	111.1	L429 E430 R436 H437	L429-R433 VanDerWaalsContact O-CG 3.3Å; L429-R433 WeakPolarHBondContact O-CG 3.47Å; L429-R433 PolarHBondContact O-N 2.96Å; E430-R433 WeakPolarHBondContact O-CB 3.36Å; E430-R433 PolarHBondContact O-N 3.45Å; E430-R433 VanDerWaalsContact O-N 3.12Å; R433-R436 PolarHBondContact O-N 3.01Å; R433-H437 WeakPolarHBondContact O-CB 3.37Å; R433-H437 PolarHBondContact O-N 2.87Å
434	V	97	Very high	95.1	Very high	73 Å²	73	89.9 Å²	89.9	44%	0.442	40%	0.402	S	S	.	.	H	α-helix	trans	-60.4	-46.9	177.7	173.2	0	0	0	0	110.8	A397 E430 A431 R436 H437 L438	A397-V434 HydrophobicContact CB-CG1 4.36Å; E430-V434 WeakPolarHBondContact O-CG2 3.37Å; E430-V434 PolarHBondContact O-N 3.38Å; A431-V434 PolarHBondContact O-N 3.38Å; V434-R436 PolarHBondContact O-N 2.86Å; V434-H437 PolarHBondContact O-N 3.09Å; V434-L438 HydrophobicContact CG1-CD1 4Å; V434-L438 HydrophobicContact CG1-CG 4.48Å; V434-L438 WeakPolarHBondContact O-CG 3.28Å; V434-L438 PolarHBondContact O-N 3.44Å
435	F	97.8	Very high	95.2	Very high	52 Å²	52	87.8 Å²	87.8	23%	0.228	39%	0.393	C	S	.	.	H	α-helix	trans	-60	-46.8	177.1	175.9	-100.7	0	0	0	112.2	I394 A397 A398 V401 A431 I432 H437 L438 R439	I394-F435 HydrophobicContact CG2-CD2 4.37Å; I394-F435 HydrophobicContact CG2-CE2 3.8Å; A397-F435 HydrophobicContact CB-CB 4.23Å; A397-F435 HydrophobicContact CB-CD2 4.31Å; A398-F435 HydrophobicContact CB-CD2 4.13Å; A398-F435 HydrophobicContact CB-CE2 3.89Å; V401-F435 HydrophobicContact CG2-CB 4.06Å; A431-F435 WeakPolarHBondContact O-CB 3.29Å; A431-F435 PolarHBondContact O-N 2.97Å; I432-F435 PolarHBondContact O-N 3.14Å; F435-H437 PolarHBondContact O-N 3.11Å; F435-L438 PolarHBondContact O-N 3.36Å; F435-R439 WeakPolarHBondContact O-CB 3.35Å; F435-R439 PolarHBondContact O-N 3.07Å
436	R	97.1	Very high	95.1	Very high	172 Å²	172	89.8 Å²	89.8	65%	0.649	40%	0.396	S	S	*	.	H	α-helix	trans	-61.3	-43.9	176.9	-75.5	179.6	179.6	-169.2	1	111.6	I432 R433 V434 R439 L440	I432-R436 HydrophobicContact CG2-CG 4.34Å; I432-R436 WeakPolarHBondContact O-CB 3.26Å; I432-R436 VanDerWaalsContact O-CG 3.31Å; I432-R436 WeakPolarHBondContact O-CG 3.38Å; I432-R436 PolarHBondContact O-N 3.01Å; R433-R436 PolarHBondContact O-N 3.01Å; V434-R436 PolarHBondContact O-N 2.86Å; R436-R439 PolarHBondContact O-N 2.95Å; R436-L440 WeakPolarHBondContact O-CG 3.5Å; R436-L440 PolarHBondContact O-N 3.37Å
437	H	96.6	Very high	94.8	Very high	122 Å²	122	86.9 Å²	86.9	57%	0.565	39%	0.392	S	S	*	.	H	α-helix	trans	-60.5	-47.1	177.2	178.8	77.4	0	0	0	111.8	R433 V434 F435 R439 L440 K441	R433-H437 WeakPolarHBondContact O-CB 3.37Å; R433-H437 PolarHBondContact O-N 2.87Å; V434-H437 PolarHBondContact O-N 3.09Å; F435-H437 PolarHBondContact O-N 3.11Å; H437-R439 PolarHBondContact O-N 3.02Å; H437-L440 PolarHBondContact O-N 3.38Å; H437-K441 PolarHBondContact O-N 3.46Å
438	L	96.9	Very high	94.3	Very high	21 Å²	21	90.8 Å²	90.8	11%	0.11	40%	0.401	C	S	.	.	H	α-helix	trans	-62.9	-40.4	177.2	-70.2	171.3	0	0	0	112.2	R393 I394 A397 V434 F435 L440 K441 Q442	R393-L438 HydrophobicContact CB-CD1 3.98Å; R393-L438 HydrophobicContact CB-CD2 4.21Å; I394-L438 HydrophobicContact CD1-CB 4.47Å; I394-L438 HydrophobicContact CG1-CB 3.71Å; A397-L438 HydrophobicContact CB-CD1 3.75Å; V434-L438 HydrophobicContact CG1-CD1 4Å; V434-L438 HydrophobicContact CG1-CG 4.48Å; V434-L438 WeakPolarHBondContact O-CG 3.28Å; V434-L438 PolarHBondContact O-N 3.44Å; F435-L438 PolarHBondContact O-N 3.36Å; L438-L440 PolarHBondContact O-N 2.69Å; L438-K441 PolarHBondContact O-N 3.06Å; L438-Q442 PolarHBondContact O-N 2.95Å
439	R	95.1	Very high	93.8	Very high	131 Å²	131	92 Å²	92	49%	0.494	41%	0.409	S	S	.	.	H	α-helix	trans	-67.1	-33.7	177.3	-167.4	174.6	178.7	-176.6	0.1	112.7	F435 R436 H437 R443	F435-R439 WeakPolarHBondContact O-CB 3.35Å; F435-R439 PolarHBondContact O-N 3.07Å; R436-R439 PolarHBondContact O-N 2.95Å; H437-R439 PolarHBondContact O-N 3.02Å; R439-R443 PolarHBondContact O-N 2.93Å
440	L	95.3	Very high	93	Very high	90 Å²	90	90.1 Å²	90.1	47%	0.471	40%	0.403	S	S	.	.	H	α-helix	trans	-69	-42.2	171.6	-73.8	171.2	0	0	0	111.4	R436 H437 L438 Q442 R443 K444	R436-L440 WeakPolarHBondContact O-CG 3.5Å; R436-L440 PolarHBondContact O-N 3.37Å; H437-L440 PolarHBondContact O-N 3.38Å; L438-L440 PolarHBondContact O-N 2.69Å; L440-Q442 VanDerWaalsContact C-N 3.32Å; L440-Q442 PolarHBondContact O-N 3.33Å; L440-R443 PolarHBondContact O-N 3.43Å; L440-K444 PolarHBondContact O-N 2.79Å; L440-K444 VanDerWaalsContact O-N 3.09Å
441	K	94.2	Very high	92.3	Very high	104 Å²	104	90.8 Å²	90.8	45%	0.452	41%	0.406	S	S	.	.	H	α-helix	trans	-60.5	-41.2	175.9	-166.9	178.6	-179.7	174.9	0	111.8	I390 H437 L438 K444 L445	I390-K441 HydrophobicContact CD1-CD 4.06Å; I390-K441 HydrophobicContact CD1-CG 3.94Å; H437-K441 PolarHBondContact O-N 3.46Å; L438-K441 PolarHBondContact O-N 3.06Å; K441-K444 PolarHBondContact O-N 2.89Å; K441-L445 PolarHBondContact O-N 2.77Å
442	Q	94.3	Very high	91.2	Very high	42 Å²	42	92.5 Å²	92.5	20%	0.196	41%	0.412	C	S	.	.	H	α-helix	trans	-62	-42.4	174.8	-167.3	-176.7	20.3	0	0	112.5	I390 S391 I394 L438 L440 L445 R446	I390-Q442 HydrophobicContact CG2-CB 3.71Å; I390-Q442 HydrophobicContact CG2-CG 4.11Å; S391-Q442 PolarHBondContact OG-NE2 3.41Å; I394-Q442 HydrophobicContact CD1-CB 3.87Å; I394-Q442 HydrophobicContact CD1-CG 4.25Å; L438-Q442 PolarHBondContact O-N 2.95Å; L440-Q442 VanDerWaalsContact C-N 3.32Å; L440-Q442 PolarHBondContact O-N 3.33Å; Q442-L445 PolarHBondContact O-N 2.72Å; Q442-R446 PolarHBondContact O-N 2.94Å
443	R	93.1	Very high	90.4	Very high	113 Å²	113	92.1 Å²	92.1	43%	0.426	41%	0.412	S	S	.	.	H	α-helix	trans	-59.7	-52.5	176.6	-78.7	-174.8	-121	169.7	-4.1	111.3	R439 L440 L445 R446 D447	R439-R443 PolarHBondContact O-N 2.93Å; L440-R443 PolarHBondContact O-N 3.43Å; R443-L445 VanDerWaalsContact C-N 3.26Å; R443-L445 PolarHBondContact O-N 3.45Å; R443-R446 PolarHBondContact O-N 3.08Å; R443-D447 PolarHBondContact O-N 3.26Å
444	K	92.6	Very high	89.6	Confident	138 Å²	138	87.2 Å²	87.2	60%	0.6	40%	0.399	S	S	*	.	H	α-helix	trans	-54.2	-44.1	177.2	-69	-175.6	177.2	-171.3	0	112	L440 K441 D447 Y448	L440-K444 PolarHBondContact O-N 2.79Å; L440-K444 VanDerWaalsContact O-N 3.09Å; K441-K444 PolarHBondContact O-N 2.89Å; K444-D447 PolarHBondContact O-N 3.05Å; K444-Y448 WeakPolarHBondContact O-CD2 3.28Å; K444-Y448 PolarHBondContact O-N 3.11Å; K444-Y448 VanDerWaalsContact O-N 3.14Å
445	L	91.3	Very high	88.8	Confident	6 Å²	6	88.9 Å²	88.9	3%	0.031	41%	0.406	C	S	.	.	H	α-helix	trans	-61.2	-46.5	176.6	177.4	55.8	0	0	0	112.3	F383 M386 D387 I390 K441 Q442 R443 D447 Y448 V449	F383-L445 HydrophobicContact CB-CD1 4.06Å; F383-L445 HydrophobicContact CD1-CD1 3.37Å; F383-L445 HydrophobicContact CE1-CD1 4.05Å; F383-L445 HydrophobicContact CG-CD1 3.99Å; M386-L445 HydrophobicContact CB-CD2 4.01Å; M386-L445 HydrophobicContact CE-CD1 3.35Å; M386-L445 HydrophobicContact CE-CD2 3.98Å; M386-L445 HydrophobicContact CE-CG 4.23Å; M386-L445 HydrophobicContact CG-CD2 3.87Å; D387-L445 HydrophobicContact CB-CD2 3.81Å; I390-L445 HydrophobicContact CD1-CD2 3.83Å; K441-L445 PolarHBondContact O-N 2.77Å; Q442-L445 PolarHBondContact O-N 2.72Å; R443-L445 VanDerWaalsContact C-N 3.26Å; R443-L445 PolarHBondContact O-N 3.45Å; L445-D447 VanDerWaalsContact C-N 3.27Å; L445-D447 PolarHBondContact O-N 3.42Å; L445-Y448 PolarHBondContact O-N 2.88Å; L445-V449 HydrophobicContact CD1-CG2 4.3Å; L445-V449 WeakPolarHBondContact O-CG2 3.34Å; L445-V449 PolarHBondContact O-N 3.28Å
446	R	88	Confident	88.1	Confident	135 Å²	135	89 Å²	89	51%	0.509	41%	0.411	S	S	.	.	H	α-helix	trans	-63	-36.2	178.3	-177.3	172.5	58.7	-139.2	2.9	112	Q442 R443 V449 S450	Q442-R446 PolarHBondContact O-N 2.94Å; R443-R446 PolarHBondContact O-N 3.08Å; R446-V449 PolarHBondContact O-N 3.33Å; R446-S450 PolarHBondContact O-N 3.49Å
447	D	87.3	Confident	87.6	Confident	98 Å²	98	85 Å²	85	52%	0.524	40%	0.399	S	S	.	.	H	α-helix	trans	-63.1	-44.9	176.6	-57.2	-24.6	0	0	0	110.3	R443 K444 L445 V449 S450 E451	R443-D447 PolarHBondContact O-N 3.26Å; K444-D447 PolarHBondContact O-N 3.05Å; L445-D447 VanDerWaalsContact C-N 3.27Å; L445-D447 PolarHBondContact O-N 3.42Å; D447-V449 VanDerWaalsContact C-N 3.35Å; D447-V449 PolarHBondContact O-N 3.34Å; D447-S450 PolarHBondContact O-N 3.45Å; D447-E451 PolarHBondContact O-N 2.9Å
448	Y	84.5	Confident	87.1	Confident	134 Å²	134	85 Å²	85	53%	0.525	40%	0.4	S	S	.	.	H	α-helix	trans	-61.2	-39	172.5	-71.6	-62.1	0	0	0	113.4	K444 L445 M452	K444-Y448 WeakPolarHBondContact O-CD2 3.28Å; K444-Y448 PolarHBondContact O-N 3.11Å; K444-Y448 VanDerWaalsContact O-N 3.14Å; L445-Y448 PolarHBondContact O-N 2.88Å; Y448-M452 PolarHBondContact O-N 3.43Å
449	V	84.1	Confident	86.6	Confident	47 Å²	47	89.4 Å²	89.4	29%	0.285	42%	0.42	S	S	.	.	H	α-helix	trans	-68.7	-36.9	176.8	172.9	0	0	0	0	111	F383 L445 R446 D447 M452 V453	F383-V449 HydrophobicContact CB-CG2 3.82Å; F383-V449 HydrophobicContact CG-CG2 4.35Å; L445-V449 HydrophobicContact CD1-CG2 4.3Å; L445-V449 WeakPolarHBondContact O-CG2 3.34Å; L445-V449 PolarHBondContact O-N 3.28Å; R446-V449 PolarHBondContact O-N 3.33Å; D447-V449 VanDerWaalsContact C-N 3.35Å; D447-V449 PolarHBondContact O-N 3.34Å; V449-M452 PolarHBondContact O-N 2.77Å; V449-V453 VanDerWaalsContact O-CG2 3.25Å; V449-V453 WeakPolarHBondContact O-CG2 3.43Å; V449-V453 PolarHBondContact O-N 3.07Å
450	S	81.6	Confident	86.4	Confident	45 Å²	45	88.4 Å²	88.4	32%	0.315	42%	0.423	S	S	.	.	H	α-helix	trans	-62.6	-50.1	175	-158.8	0	0	0	0	110.3	R446 D447 M452 V453 D454	R446-S450 PolarHBondContact O-N 3.49Å; D447-S450 PolarHBondContact O-N 3.45Å; S450-M452 VanDerWaalsContact C-N 3.26Å; S450-M452 PolarHBondContact O-N 2.9Å; S450-V453 CarbonylContact O-C 3.49Å; S450-V453 WeakPolarHBondContact O-CA 3.18Å; S450-V453 PolarHBondContact O-N 2.93Å; S450-D454 PolarHBondContact O-N 3.22Å; S450-D454 PolarHBondContact OG-OD1 2.98Å
451	E	81.3	Confident	86.3	Confident	140 Å²	140	88.6 Å²	88.6	65%	0.654	42%	0.423	S	S	*	.	H	α-helix	trans	-54.4	-40.7	179.2	-169.4	-177.7	177.5	0	0	112.4	D447 V453 D454	D447-E451 PolarHBondContact O-N 2.9Å; E451-V453 PolarHBondContact O-N 3.01Å; E451-D454 WeakPolarHBondContact CA-OD2 3.5Å
452	M	74.1	Confident	86	Confident	49 Å²	49	89.2 Å²	89.2	24%	0.241	43%	0.429	C	S	.	.	H	α-helix	trans	-65.4	-23.9	176.4	-84.6	-174.3	62.7	0	0	114.6	K376 K379 H380 F383 Y448 V449 S450	K376-M452 HydrophobicContact CG-CE 4.29Å; K379-M452 HydrophobicContact CB-CE 3.92Å; K379-M452 HydrophobicContact CB-SD 4.21Å; H380-M452 HydrophobicContact CB-CE 4.18Å; F383-M452 HydrophobicContact CD2-SD 3.59Å; F383-M452 VanDerWaalsContact CD2-SD 3.59Å; F383-M452 HydrophobicContact CE2-SD 3.56Å; F383-M452 VanDerWaalsContact CE2-SD 3.56Å; Y448-M452 PolarHBondContact O-N 3.43Å; V449-M452 PolarHBondContact O-N 2.77Å; S450-M452 VanDerWaalsContact C-N 3.26Å; S450-M452 PolarHBondContact O-N 2.9Å
453	V	79.7	Confident	85.8	Confident	43 Å²	43	90.9 Å²	90.9	26%	0.261	45%	0.445	S	S	.	.	H	α-helix	trans	-110	-7.8	-171.7	-173.7	0	0	0	0	112	V449 S450 E451 L455 P456 K457	V449-V453 VanDerWaalsContact O-CG2 3.25Å; V449-V453 WeakPolarHBondContact O-CG2 3.43Å; V449-V453 PolarHBondContact O-N 3.07Å; S450-V453 CarbonylContact O-C 3.49Å; S450-V453 WeakPolarHBondContact O-CA 3.18Å; S450-V453 PolarHBondContact O-N 2.93Å; E451-V453 PolarHBondContact O-N 3.01Å; V453-L455 PolarHBondContact O-N 2.96Å; V453-P456 WeakPolarHBondContact O-CD 3.35Å; V453-K457 HydrophobicContact CB-CD 4.49Å; V453-K457 HydrophobicContact CG1-CD 3.88Å; V453-K457 HydrophobicContact CG1-CG 3.93Å; V453-K457 WeakPolarHBondContact O-CB 3.28Å; V453-K457 WeakPolarHBondContact O-CG 3.35Å; V453-K457 PolarHBondContact O-N 2.99Å
454	D	80.7	Confident	85.8	Confident	76 Å²	76	89.9 Å²	89.9	41%	0.406	45%	0.448	S	S	.	.	H	α-helix	trans	-63.4	-40.9	-176.9	-69.7	-22.9	0	0	0	112.9	S450 E451 K457 M458	S450-D454 PolarHBondContact O-N 3.22Å; S450-D454 PolarHBondContact OG-OD1 2.98Å; E451-D454 WeakPolarHBondContact CA-OD2 3.5Å; D454-K457 PolarHBondContact O-N 3.01Å; D454-M458 WeakPolarHBondContact O-CB 3.42Å; D454-M458 PolarHBondContact O-N 2.93Å
455	L	79.4	Confident	85.8	Confident	109 Å²	109	88.7 Å²	88.7	57%	0.571	45%	0.447	S	S	*	.	H	α-helix	trans	-65.7	-49.3	178.1	-177.8	71.1	0	0	0	112.9	V453 K457 M458 Q459	V453-L455 PolarHBondContact O-N 2.96Å; L455-K457 VanDerWaalsContact C-N 3.35Å; L455-K457 PolarHBondContact O-N 2.97Å; L455-M458 HydrophobicContact CD1-CE 4.31Å; L455-M458 PolarHBondContact O-N 3.5Å; L455-Q459 PolarHBondContact O-N 3.5Å
456	P	82.9	Confident	85.9	Confident	53 Å²	53	92.1 Å²	92.1	34%	0.344	47%	0.472	S	S	.	.	H	α-helix	trans	-58.6	-40.3	171.4	-25.4	32.4	0	0	0	114	V453 M458 Q459 M460	V453-P456 WeakPolarHBondContact O-CD 3.35Å; P456-M458 VanDerWaalsContact C-N 3.35Å; P456-Q459 PolarHBondContact O-N 2.86Å; P456-M460 PolarHBondContact O-N 3.38Å
457	K	87.3	Confident	86.2	Confident	90 Å²	90	88 Å²	88	39%	0.391	47%	0.466	S	S	.	.	H	α-helix	trans	-63	-41.5	176	-81.2	168.1	177.9	174.6	0	111.7	V453 D454 L455 Q459 M460 I461	V453-K457 HydrophobicContact CB-CD 4.49Å; V453-K457 HydrophobicContact CG1-CD 3.88Å; V453-K457 HydrophobicContact CG1-CG 3.93Å; V453-K457 WeakPolarHBondContact O-CB 3.28Å; V453-K457 WeakPolarHBondContact O-CG 3.35Å; V453-K457 PolarHBondContact O-N 2.99Å; D454-K457 PolarHBondContact O-N 3.01Å; L455-K457 VanDerWaalsContact C-N 3.35Å; L455-K457 PolarHBondContact O-N 2.97Å; K457-Q459 VanDerWaalsContact C-N 3.33Å; K457-Q459 PolarHBondContact O-N 3.07Å; K457-M460 WeakPolarHBondContact O-CB 3.5Å; K457-M460 PolarHBondContact O-N 3.28Å; K457-I461 WeakPolarHBondContact O-CB 3.31Å; K457-I461 VanDerWaalsContact O-CG1 3.25Å; K457-I461 WeakPolarHBondContact O-CG1 3.3Å; K457-I461 PolarHBondContact O-N 3.34Å
458	M	85.3	Confident	86.5	Confident	122 Å²	122	88.2 Å²	88.2	60%	0.601	47%	0.467	S	S	*	.	H	α-helix	trans	-62.9	-41.1	177.1	-166.1	-179.5	84	0	0	111.3	D454 L455 P456 I461 M462	D454-M458 WeakPolarHBondContact O-CB 3.42Å; D454-M458 PolarHBondContact O-N 2.93Å; L455-M458 HydrophobicContact CD1-CE 4.31Å; L455-M458 PolarHBondContact O-N 3.5Å; P456-M458 VanDerWaalsContact C-N 3.35Å; M458-I461 PolarHBondContact O-N 3.33Å; M458-M462 VanDerWaalsContact O-CB 3.3Å; M458-M462 WeakPolarHBondContact O-CB 3.04Å; M458-M462 PolarHBondContact O-N 2.96Å
459	Q	87	Confident	86.9	Confident	113 Å²	113	91.1 Å²	91.1	53%	0.528	48%	0.478	S	S	.	.	H	α-helix	trans	-62.2	-42.8	173.7	-72	-179.8	-31.1	0	0	112	L455 P456 K457 M462 C463	L455-Q459 PolarHBondContact O-N 3.5Å; P456-Q459 PolarHBondContact O-N 2.86Å; K457-Q459 VanDerWaalsContact C-N 3.33Å; K457-Q459 PolarHBondContact O-N 3.07Å; Q459-M462 PolarHBondContact O-N 3.2Å; Q459-C463 PolarHBondContact O-N 2.95Å; Q459-C463 PolarHBondContact O-SG 3.2Å; Q459-C463 VanDerWaalsContact O-SG 3.33Å
460	M	91.4	Very high	87.4	Confident	110 Å²	110	93.4 Å²	93.4	54%	0.542	49%	0.488	S	S	.	.	H	α-helix	trans	-62	-49.8	176.2	-172.8	-179.1	75	0	0	111.6	P456 K457 M462 C463 D464	P456-M460 PolarHBondContact O-N 3.38Å; K457-M460 WeakPolarHBondContact O-CB 3.5Å; K457-M460 PolarHBondContact O-N 3.28Å; M460-M462 VanDerWaalsContact C-N 3.28Å; M460-M462 PolarHBondContact O-N 3.42Å; M460-C463 PolarHBondContact O-N 2.94Å; M460-D464 PolarHBondContact O-N 3.49Å
461	I	92.3	Very high	88	Confident	93 Å²	93	96 Å²	96	48%	0.477	50%	0.498	S	S	.	.	H	α-helix	trans	-59.4	-40	177.4	-67.2	163.8	0	0	0	111	K457 M458 D464 L465	K457-I461 WeakPolarHBondContact O-CB 3.31Å; K457-I461 VanDerWaalsContact O-CG1 3.25Å; K457-I461 WeakPolarHBondContact O-CG1 3.3Å; K457-I461 PolarHBondContact O-N 3.34Å; M458-I461 PolarHBondContact O-N 3.33Å; I461-D464 PolarHBondContact O-N 3.43Å; I461-L465 HydrophobicContact CG2-CD1 3.74Å; I461-L465 HydrophobicContact CG2-CG 4.43Å; I461-L465 WeakPolarHBondContact O-CB 3.48Å; I461-L465 WeakPolarHBondContact O-CD1 3.41Å; I461-L465 WeakPolarHBondContact O-CG 3.43Å; I461-L465 PolarHBondContact O-N 2.84Å
462	M	88.3	Confident	88.5	Confident	117 Å²	117	92.6 Å²	92.6	58%	0.576	49%	0.49	S	S	*	.	H	α-helix	trans	-65.5	-42.5	177.4	-174.1	-176.7	74.3	0	0	112	M458 Q459 M460 L465 S466	M458-M462 VanDerWaalsContact O-CB 3.3Å; M458-M462 WeakPolarHBondContact O-CB 3.04Å; M458-M462 PolarHBondContact O-N 2.96Å; Q459-M462 PolarHBondContact O-N 3.2Å; M460-M462 VanDerWaalsContact C-N 3.28Å; M460-M462 PolarHBondContact O-N 3.42Å; M462-L465 PolarHBondContact O-N 3.34Å; M462-S466 WeakPolarHBondContact O-CB 3.32Å; M462-S466 PolarHBondContact O-N 3.34Å
463	C	89.9	Confident	89.4	Confident	78 Å²	78	96.4 Å²	96.4	53%	0.527	50%	0.503	S	S	.	.	H	α-helix	trans	-62.3	-43.9	174.4	-71.9	0	0	0	0	111.5	Q459 M460 S466 A467	Q459-C463 PolarHBondContact O-N 2.95Å; Q459-C463 PolarHBondContact O-SG 3.2Å; Q459-C463 VanDerWaalsContact O-SG 3.33Å; M460-C463 PolarHBondContact O-N 2.94Å; C463-S466 PolarHBondContact O-N 2.86Å; C463-A467 WeakPolarHBondContact O-CB 3.29Å; C463-A467 PolarHBondContact O-N 2.9Å
464	D	92.7	Very high	90.1	Very high	92 Å²	92	101.2 Å²	101.2	49%	0.492	52%	0.516	S	S	.	.	H	α-helix	trans	-64.2	-42.5	177.9	-67.8	-18.2	0	0	0	111.4	M460 I461 A467 N468	M460-D464 PolarHBondContact O-N 3.49Å; I461-D464 PolarHBondContact O-N 3.43Å; D464-A467 PolarHBondContact O-N 2.91Å; D464-N468 WeakPolarHBondContact O-CB 3.19Å; D464-N468 PolarHBondContact O-N 3.05Å
465	L	93.1	Very high	90.7	Very high	112 Å²	112	102.1 Å²	102.1	59%	0.586	52%	0.518	S	S	*	.	H	α-helix	trans	-61.8	-44.9	173.7	-82.4	161.1	0	0	0	111.8	I461 M462 A467 N468 W469	I461-L465 HydrophobicContact CG2-CD1 3.74Å; I461-L465 HydrophobicContact CG2-CG 4.43Å; I461-L465 WeakPolarHBondContact O-CB 3.48Å; I461-L465 WeakPolarHBondContact O-CD1 3.41Å; I461-L465 WeakPolarHBondContact O-CG 3.43Å; I461-L465 PolarHBondContact O-N 2.84Å; M462-L465 PolarHBondContact O-N 3.34Å; L465-A467 VanDerWaalsContact C-N 3.32Å; L465-A467 PolarHBondContact O-N 3.36Å; L465-N468 PolarHBondContact O-N 3.3Å; L465-W469 VanDerWaalsContact O-CB 3.29Å; L465-W469 WeakPolarHBondContact O-CB 3.2Å; L465-W469 PolarHBondContact O-N 3.37Å
466	S	93.9	Very high	91.4	Very high	78 Å²	78	101.5 Å²	101.5	55%	0.545	52%	0.515	S	S	.	.	H	α-helix	trans	-63.3	-39.8	177.5	-174.2	0	0	0	0	111.5	M462 C463 N470	M462-S466 WeakPolarHBondContact O-CB 3.32Å; M462-S466 PolarHBondContact O-N 3.34Å; C463-S466 PolarHBondContact O-N 2.86Å; S466-N470 WeakPolarHBondContact O-CB 3.47Å; S466-N470 PolarHBondContact O-N 2.94Å
467	A	93.1	Very high	92	Very high	48 Å²	48	103.3 Å²	103.3	40%	0.397	52%	0.519	S	S	.	.	H	α-helix	trans	-65.6	-45.6	176.1	0	0	0	0	0	111.3	C463 D464 L465 W469 N470 N471	C463-A467 WeakPolarHBondContact O-CB 3.29Å; C463-A467 PolarHBondContact O-N 2.9Å; D464-A467 PolarHBondContact O-N 2.91Å; L465-A467 VanDerWaalsContact C-N 3.32Å; L465-A467 PolarHBondContact O-N 3.36Å; A467-W469 PolarHBondContact O-N 3.27Å; A467-N470 PolarHBondContact O-N 3.32Å; A467-N471 VanDerWaalsContact O-CG 3.29Å; A467-N471 PolarHBondContact O-N 2.71Å; A467-N471 PolarHBondContact O-ND2 3.45Å
468	N	94.9	Very high	92.4	Very high	103 Å²	103	105.1 Å²	105.1	55%	0.551	53%	0.529	S	S	*	.	H	α-helix	trans	-63.3	-40.2	175.7	-84.6	-3.9	0	0	0	112.7	D464 L465 N470 N471 S472	D464-N468 WeakPolarHBondContact O-CB 3.19Å; D464-N468 PolarHBondContact O-N 3.05Å; L465-N468 PolarHBondContact O-N 3.3Å; N468-N470 VanDerWaalsContact C-N 3.34Å; N468-N471 PolarHBondContact O-N 3.33Å; N468-S472 WeakPolarHBondContact O-CB 3.34Å; N468-S472 PolarHBondContact O-N 3.09Å; N468-S472 PolarHBondContact O-OG 3.49Å
469	W	92.5	Very high	92.9	Very high	196 Å²	196	106.5 Å²	106.5	74%	0.742	53%	0.527	S	S	*	.	H	α-helix	trans	-61.8	-45.1	175.2	-175.3	-90.3	0	0	0	110.8	L465 A467 N471 S472 Y473	L465-W469 VanDerWaalsContact O-CB 3.29Å; L465-W469 WeakPolarHBondContact O-CB 3.2Å; L465-W469 PolarHBondContact O-N 3.37Å; A467-W469 PolarHBondContact O-N 3.27Å; W469-N471 VanDerWaalsContact C-N 3.34Å; W469-N471 PolarHBondContact O-N 2.97Å; W469-S472 PolarHBondContact O-N 3.42Å; W469-Y473 WeakPolarHBondContact O-CB 3.38Å; W469-Y473 PolarHBondContact O-N 3.33Å
470	N	93.3	Very high	93.2	Very high	94 Å²	94	105.7 Å²	105.7	50%	0.503	53%	0.525	S	S	.	.	H	α-helix	trans	-64.7	-39.1	179	-155.4	31.9	0	0	0	111.9	S466 A467 N468 Y473 R474	S466-N470 WeakPolarHBondContact O-CB 3.47Å; S466-N470 PolarHBondContact O-N 2.94Å; A467-N470 PolarHBondContact O-N 3.32Å; N468-N470 VanDerWaalsContact C-N 3.34Å; N470-Y473 PolarHBondContact O-N 3.36Å; N470-R474 WeakPolarHBondContact O-CG 3.43Å; N470-R474 PolarHBondContact O-N 3.08Å
471	N	94.4	Very high	93.4	Very high	99 Å²	99	104.8 Å²	104.8	53%	0.529	52%	0.522	S	S	.	.	H	α-helix	trans	-63.3	-45.3	173.6	-70.8	-22.3	0	0	0	111.8	A467 N468 W469 Y473 R474 E475	A467-N471 VanDerWaalsContact O-CG 3.29Å; A467-N471 PolarHBondContact O-N 2.71Å; A467-N471 PolarHBondContact O-ND2 3.45Å; N468-N471 PolarHBondContact O-N 3.33Å; W469-N471 VanDerWaalsContact C-N 3.34Å; W469-N471 PolarHBondContact O-N 2.97Å; N471-Y473 VanDerWaalsContact C-N 3.33Å; N471-Y473 PolarHBondContact O-N 2.96Å; N471-R474 PolarHBondContact O-N 3.42Å; N471-E475 PolarHBondContact O-N 3.17Å
472	S	93.2	Very high	93.6	Very high	69 Å²	69	106.1 Å²	106.1	48%	0.483	53%	0.525	S	S	.	.	H	α-helix	trans	-65	-38.2	178	-55.9	0	0	0	0	111.8	N468 W469 E475 L476	N468-S472 WeakPolarHBondContact O-CB 3.34Å; N468-S472 PolarHBondContact O-N 3.09Å; N468-S472 PolarHBondContact O-OG 3.49Å; W469-S472 PolarHBondContact O-N 3.42Å; S472-E475 PolarHBondContact O-N 3.18Å; S472-L476 WeakPolarHBondContact O-CB 3.49Å; S472-L476 PolarHBondContact O-N 3.47Å
473	Y	92.8	Very high	93.9	Very high	129 Å²	129	106.9 Å²	106.9	51%	0.506	53%	0.529	S	S	.	.	H	α-helix	trans	-62.5	-46.2	174.7	-179	-91.5	0	0	0	111.3	W469 N470 N471 E475 L476 E477	W469-Y473 WeakPolarHBondContact O-CB 3.38Å; W469-Y473 PolarHBondContact O-N 3.33Å; N470-Y473 PolarHBondContact O-N 3.36Å; N471-Y473 VanDerWaalsContact C-N 3.33Å; N471-Y473 PolarHBondContact O-N 2.96Å; Y473-E475 VanDerWaalsContact C-N 3.31Å; Y473-E475 PolarHBondContact O-N 2.64Å; Y473-L476 WeakPolarHBondContact O-CB 3.35Å; Y473-L476 PolarHBondContact O-N 3.49Å; Y473-E477 WeakPolarHBondContact O-CB 3.39Å; Y473-E477 PolarHBondContact O-N 2.94Å
474	R	92.8	Very high	94.2	Very high	145 Å²	145	108.4 Å²	108.4	55%	0.547	53%	0.528	S	S	.	.	H	α-helix	trans	-61.1	-39.7	175.4	-73.4	177.9	68.5	90.8	3.5	112.3	N470 N471 E477 Q478	N470-R474 WeakPolarHBondContact O-CG 3.43Å; N470-R474 PolarHBondContact O-N 3.08Å; N471-R474 PolarHBondContact O-N 3.42Å; R474-E477 PolarHBondContact O-N 3.43Å; R474-Q478 WeakPolarHBondContact O-CG 3.42Å; R474-Q478 PolarHBondContact O-N 3.37Å
475	E	94.3	Very high	94.3	Very high	94 Å²	94	110.1 Å²	110.1	44%	0.439	53%	0.533	S	S	.	.	H	α-helix	trans	-65.8	-41.2	175.9	-169.4	-178	169.4	0	0	111.5	N471 S472 Y473 Q478 R479	N471-E475 PolarHBondContact O-N 3.17Å; S472-E475 PolarHBondContact O-N 3.18Å; Y473-E475 VanDerWaalsContact C-N 3.31Å; Y473-E475 PolarHBondContact O-N 2.64Å; E475-Q478 PolarHBondContact O-N 2.75Å; E475-R479 WeakPolarHBondContact O-CG 3.49Å; E475-R479 PolarHBondContact O-N 2.91Å; E475-R479 IonicContact OE1-CZ 3.48Å; E475-R479 IonicContact OE1-NE 3.56Å; E475-R479 IonicContact OE1-NH2 2.68Å; E475-R479 PolarHBondContact OE1-NH2 3.26Å
476	L	93.8	Very high	94.3	Very high	96 Å²	96	109.6 Å²	109.6	50%	0.503	53%	0.526	S	S	.	.	H	α-helix	trans	-62.9	-44.3	175.2	-175.7	67.4	0	0	0	111.5	S472 Y473 Q478 R479 I480	S472-L476 WeakPolarHBondContact O-CB 3.49Å; S472-L476 PolarHBondContact O-N 3.47Å; Y473-L476 WeakPolarHBondContact O-CB 3.35Å; Y473-L476 PolarHBondContact O-N 3.49Å; L476-Q478 VanDerWaalsContact C-N 3.33Å; L476-Q478 PolarHBondContact O-N 2.75Å; L476-R479 PolarHBondContact O-N 2.92Å; L476-R479 VanDerWaalsContact O-N 3.15Å; L476-I480 HydrophobicContact CG-CD1 4.09Å; L476-I480 WeakPolarHBondContact O-CG1 3.41Å; L476-I480 PolarHBondContact O-N 2.9Å
477	E	95.2	Very high	94.4	Very high	92 Å²	92	111.4 Å²	111.4	43%	0.43	53%	0.529	S	S	.	.	H	α-helix	trans	-58.9	-44.3	176.1	-172.8	176.5	-160.2	0	0	111.2	Y473 R474 R479 I480 L481	Y473-E477 WeakPolarHBondContact O-CB 3.39Å; Y473-E477 PolarHBondContact O-N 2.94Å; R474-E477 PolarHBondContact O-N 3.43Å; E477-R479 VanDerWaalsContact C-N 3.34Å; E477-R479 PolarHBondContact O-N 3.47Å; E477-I480 PolarHBondContact O-N 2.86Å; E477-L481 HydrophobicContact CG-CD1 4.47Å; E477-L481 WeakPolarHBondContact O-CG 3.37Å; E477-L481 PolarHBondContact O-N 3.24Å
478	Q	95.3	Very high	94.4	Very high	128 Å²	128	113.9 Å²	113.9	60%	0.598	54%	0.536	S	S	*	.	H	α-helix	trans	-60.9	-40.4	174.4	-75	179.4	-23.5	0	0	112.8	R474 E475 L476 F482	R474-Q478 WeakPolarHBondContact O-CG 3.42Å; R474-Q478 PolarHBondContact O-N 3.37Å; E475-Q478 PolarHBondContact O-N 2.75Å; L476-Q478 VanDerWaalsContact C-N 3.33Å; L476-Q478 PolarHBondContact O-N 2.75Å; Q478-F482 WeakPolarHBondContact O-CB 3.47Å; Q478-F482 PolarHBondContact O-N 3.44Å
479	R	95.9	Very high	94.4	Very high	151 Å²	151	114.2 Å²	114.2	57%	0.57	53%	0.534	S	S	*	.	H	α-helix	trans	-67.2	-37.9	176.6	-70.1	175.7	-173.6	-162.7	4.3	112.1	E475 L476 E477 F482 M483	E475-R479 WeakPolarHBondContact O-CG 3.49Å; E475-R479 PolarHBondContact O-N 2.91Å; E475-R479 IonicContact OE1-CZ 3.48Å; E475-R479 IonicContact OE1-NE 3.56Å; E475-R479 IonicContact OE1-NH2 2.68Å; E475-R479 PolarHBondContact OE1-NH2 3.26Å; L476-R479 PolarHBondContact O-N 2.92Å; L476-R479 VanDerWaalsContact O-N 3.15Å; E477-R479 VanDerWaalsContact C-N 3.34Å; E477-R479 PolarHBondContact O-N 3.47Å; R479-F482 PolarHBondContact O-N 3.37Å; R479-M483 WeakPolarHBondContact O-CB 3.44Å; R479-M483 PolarHBondContact O-N 3.49Å
480	I	95	Very high	94.5	Very high	95 Å²	95	110 Å²	110	49%	0.487	53%	0.525	S	S	.	.	H	α-helix	trans	-64.4	-48.6	175.7	-69.2	167.2	0	0	0	110	L476 E477 F482 M483 E484	L476-I480 HydrophobicContact CG-CD1 4.09Å; L476-I480 WeakPolarHBondContact O-CG1 3.41Å; L476-I480 PolarHBondContact O-N 2.9Å; E477-I480 PolarHBondContact O-N 2.86Å; I480-F482 VanDerWaalsContact C-N 3.28Å; I480-F482 PolarHBondContact O-N 3.43Å; I480-M483 CarbonylContact O-C 3.59Å; I480-M483 WeakPolarHBondContact O-CB 3.31Å; I480-M483 PolarHBondContact O-N 2.89Å; I480-M483 VanDerWaalsContact O-N 3.08Å; I480-E484 WeakPolarHBondContact O-CB 3.48Å; I480-E484 PolarHBondContact O-N 3.49Å
481	L	94.9	Very high	94.5	Very high	92 Å²	92	108.9 Å²	108.9	48%	0.482	52%	0.522	S	S	.	.	H	α-helix	trans	-59.5	-40.4	177	-71.3	171.5	0	0	0	111.9	E477 E484 Q485	E477-L481 HydrophobicContact CG-CD1 4.47Å; E477-L481 WeakPolarHBondContact O-CG 3.37Å; E477-L481 PolarHBondContact O-N 3.24Å; L481-E484 PolarHBondContact O-N 2.86Å; L481-Q485 WeakPolarHBondContact O-CG 3.26Å; L481-Q485 PolarHBondContact O-N 3.05Å
482	F	96.1	Very high	94.4	Very high	120 Å²	120	113.1 Å²	113.1	53%	0.526	53%	0.53	S	S	.	.	H	α-helix	trans	-64.8	-41.2	174.6	-179.1	-100.7	0	0	0	112.3	Q478 R479 I480 Q485 K486	Q478-F482 WeakPolarHBondContact O-CB 3.47Å; Q478-F482 PolarHBondContact O-N 3.44Å; R479-F482 PolarHBondContact O-N 3.37Å; I480-F482 VanDerWaalsContact C-N 3.28Å; I480-F482 PolarHBondContact O-N 3.43Å; F482-Q485 PolarHBondContact O-N 2.83Å; F482-K486 HydrophobicContact CD1-CG 4.41Å; F482-K486 HydrophobicContact CE1-CG 4.01Å; F482-K486 HydrophobicContact CZ-CD 4.48Å; F482-K486 HydrophobicContact CZ-CG 4.15Å; F482-K486 WeakPolarHBondContact O-CG 3.49Å; F482-K486 PolarHBondContact O-N 3.45Å
483	M	94.6	Very high	94.3	Very high	134 Å²	134	112.9 Å²	112.9	66%	0.66	53%	0.528	S	S	*	.	H	α-helix	trans	-63.6	-41.3	174.2	-89.4	-177.3	56.9	0	0	112.3	R479 I480 K486 L487	R479-M483 WeakPolarHBondContact O-CB 3.44Å; R479-M483 PolarHBondContact O-N 3.49Å; I480-M483 CarbonylContact O-C 3.59Å; I480-M483 WeakPolarHBondContact O-CB 3.31Å; I480-M483 PolarHBondContact O-N 2.89Å; I480-M483 VanDerWaalsContact O-N 3.08Å; M483-K486 PolarHBondContact O-N 2.85Å; M483-L487 PolarHBondContact O-N 2.86Å
484	E	95.4	Very high	94.2	Very high	109 Å²	109	113.6 Å²	113.6	51%	0.509	53%	0.534	S	S	.	.	H	α-helix	trans	-60.8	-47.1	177.1	-170	173.6	-170.5	0	0	110.6	I480 L481 K486 L487 D488	I480-E484 WeakPolarHBondContact O-CB 3.48Å; I480-E484 PolarHBondContact O-N 3.49Å; L481-E484 PolarHBondContact O-N 2.86Å; E484-K486 VanDerWaalsContact C-N 3.29Å; E484-K486 PolarHBondContact O-N 3.14Å; E484-L487 WeakPolarHBondContact O-CB 3.44Å; E484-L487 PolarHBondContact O-N 3.16Å; E484-L487 VanDerWaalsContact O-N 3.07Å; E484-D488 PolarHBondContact O-N 3.38Å
485	Q	95	Very high	94	Very high	129 Å²	129	112.2 Å²	112.2	60%	0.603	53%	0.534	S	S	*	.	H	α-helix	trans	-57.4	-41.6	172.9	-76.2	-179.5	-17.3	0	0	112.6	L481 F482 L487 D488 E489	L481-Q485 WeakPolarHBondContact O-CG 3.26Å; L481-Q485 PolarHBondContact O-N 3.05Å; F482-Q485 PolarHBondContact O-N 2.83Å; Q485-L487 VanDerWaalsContact C-N 3.33Å; Q485-D488 PolarHBondContact O-N 3.39Å; Q485-E489 WeakPolarHBondContact O-CB 3.48Å; Q485-E489 PolarHBondContact O-N 2.81Å
486	K	94.9	Very high	93.9	Very high	101 Å²	101	113.3 Å²	113.3	44%	0.439	54%	0.539	S	S	.	.	H	α-helix	trans	-67	-35.2	177.1	-73.8	-69.7	167.9	-154.2	0	112.5	F482 M483 E484 E489 L490	F482-K486 HydrophobicContact CD1-CG 4.41Å; F482-K486 HydrophobicContact CE1-CG 4.01Å; F482-K486 HydrophobicContact CZ-CD 4.48Å; F482-K486 HydrophobicContact CZ-CG 4.15Å; F482-K486 WeakPolarHBondContact O-CG 3.49Å; F482-K486 PolarHBondContact O-N 3.45Å; M483-K486 PolarHBondContact O-N 2.85Å; E484-K486 VanDerWaalsContact C-N 3.29Å; E484-K486 PolarHBondContact O-N 3.14Å; K486-E489 IonicContact NZ-OE2 3.35Å; K486-E489 PolarHBondContact NZ-OE2 3.28Å; K486-L490 WeakPolarHBondContact O-CB 2.95Å; K486-L490 PolarHBondContact O-N 3.49Å
487	L	94.6	Very high	93.6	Very high	115 Å²	115	112.3 Å²	112.3	60%	0.602	54%	0.537	S	S	*	.	H	α-helix	trans	-68.1	-42.3	176.6	-152.2	91.4	0	0	0	111.3	M483 E484 Q485 E489 L490 T491	M483-L487 PolarHBondContact O-N 2.86Å; E484-L487 WeakPolarHBondContact O-CB 3.44Å; E484-L487 PolarHBondContact O-N 3.16Å; E484-L487 VanDerWaalsContact O-N 3.07Å; Q485-L487 VanDerWaalsContact C-N 3.33Å; L487-E489 VanDerWaalsContact C-N 3.33Å; L487-E489 PolarHBondContact O-N 2.92Å; L487-L490 PolarHBondContact O-N 3.42Å; L487-T491 WeakPolarHBondContact O-CB 3.45Å; L487-T491 PolarHBondContact O-N 3Å; L487-T491 PolarHBondContact O-OG1 3.43Å
488	D	93.8	Very high	93.2	Very high	101 Å²	101	111 Å²	111	54%	0.54	54%	0.538	S	S	.	.	H	α-helix	trans	-61.4	-42.8	175	-77.9	-18.7	0	0	0	111.5	E484 Q485 T491 R492	E484-D488 PolarHBondContact O-N 3.38Å; Q485-D488 PolarHBondContact O-N 3.39Å; D488-T491 WeakPolarHBondContact O-CB 3.4Å; D488-T491 PolarHBondContact O-N 2.85Å; D488-R492 PolarHBondContact O-N 3.28Å
489	E	94.4	Very high	92.7	Very high	110 Å²	110	111.1 Å²	111.1	51%	0.514	54%	0.539	S	S	.	.	H	α-helix	trans	-64.9	-41	178	-165.3	154.2	-144.6	0	0	111.8	Q485 K486 L487 R492 C493	Q485-E489 WeakPolarHBondContact O-CB 3.48Å; Q485-E489 PolarHBondContact O-N 2.81Å; K486-E489 IonicContact NZ-OE2 3.35Å; K486-E489 PolarHBondContact NZ-OE2 3.28Å; L487-E489 VanDerWaalsContact C-N 3.33Å; L487-E489 PolarHBondContact O-N 2.92Å; E489-R492 WeakPolarHBondContact O-CB 3.25Å; E489-R492 PolarHBondContact O-N 3.46Å; E489-C493 PolarHBondContact O-N 2.82Å
490	L	94.2	Very high	92.1	Very high	106 Å²	106	108.9 Å²	108.9	56%	0.555	54%	0.538	S	S	*	.	H	α-helix	trans	-62.5	-42.9	173.3	-120.3	151.7	0	0	0	112.2	K486 L487 R492 C493 F494	K486-L490 WeakPolarHBondContact O-CB 2.95Å; K486-L490 PolarHBondContact O-N 3.49Å; L487-L490 PolarHBondContact O-N 3.42Å; L490-R492 VanDerWaalsContact C-N 3.3Å; L490-R492 PolarHBondContact O-N 2.91Å; L490-C493 PolarHBondContact O-N 3.29Å; L490-F494 HydrophobicContact CD2-CD2 4.26Å; L490-F494 HydrophobicContact CD2-CE2 4.5Å; L490-F494 PolarHBondContact O-N 3.28Å
491	T	93.1	Very high	91.5	Very high	72 Å²	72	109.7 Å²	109.7	44%	0.442	54%	0.542	S	S	.	.	H	α-helix	trans	-60.5	-43.1	176.5	-56.7	0	0	0	0	110.5	L487 D488 F494 Q495	L487-T491 WeakPolarHBondContact O-CB 3.45Å; L487-T491 PolarHBondContact O-N 3Å; L487-T491 PolarHBondContact O-OG1 3.43Å; D488-T491 WeakPolarHBondContact O-CB 3.4Å; D488-T491 PolarHBondContact O-N 2.85Å; T491-F494 WeakPolarHBondContact O-CB 3.2Å; T491-F494 PolarHBondContact O-N 3.39Å; T491-Q495 PolarHBondContact O-N 2.86Å
492	R	92.2	Very high	90.8	Very high	187 Å²	187	111.9 Å²	111.9	71%	0.706	55%	0.548	S	S	*	.	H	α-helix	trans	-60.6	-46.2	174.5	-116.9	-174.7	151.5	124.7	-0.4	112.7	D488 E489 L490 F494 Q495 Q496	D488-R492 PolarHBondContact O-N 3.28Å; E489-R492 WeakPolarHBondContact O-CB 3.25Å; E489-R492 PolarHBondContact O-N 3.46Å; L490-R492 VanDerWaalsContact C-N 3.3Å; L490-R492 PolarHBondContact O-N 2.91Å; R492-F494 VanDerWaalsContact C-N 3.32Å; R492-F494 PolarHBondContact O-N 3.47Å; R492-Q495 PolarHBondContact O-N 3.07Å; R492-Q496 PolarHBondContact O-N 2.79Å
493	C	91.6	Very high	90.1	Very high	64 Å²	64	112.4 Å²	112.4	43%	0.432	55%	0.552	S	S	.	*	H	α-helix	trans	-62.9	-38.3	175.5	-73.3	0	0	0	0	112	E489 L490 Q496 T497	E489-C493 PolarHBondContact O-N 2.82Å; L490-C493 PolarHBondContact O-N 3.29Å; C493-Q496 PolarHBondContact O-N 2.94Å; C493-T497 WeakPolarHBondContact O-CB 3.4Å; C493-T497 WeakPolarHBondContact O-CG2 3.41Å; C493-T497 PolarHBondContact O-N 3.47Å; C493-T497 PolarHBondContact O-OG1 2.86Å
494	F	91.1	Very high	89.3	Confident	145 Å²	145	110.6 Å²	110.6	64%	0.636	55%	0.549	S	S	*	.	H	α-helix	trans	-63.7	-42	174.8	-113.7	-77.1	0	0	0	112	L490 T491 R492 T497 S498	L490-F494 HydrophobicContact CD2-CD2 4.26Å; L490-F494 HydrophobicContact CD2-CE2 4.5Å; L490-F494 PolarHBondContact O-N 3.28Å; T491-F494 WeakPolarHBondContact O-CB 3.2Å; T491-F494 PolarHBondContact O-N 3.39Å; R492-F494 VanDerWaalsContact C-N 3.32Å; R492-F494 PolarHBondContact O-N 3.47Å; F494-T497 WeakPolarHBondContact CA-OG1 3.35Å; F494-T497 PolarHBondContact O-N 2.92Å; F494-T497 PolarHBondContact O-OG1 3.39Å; F494-S498 VanDerWaalsContact O-CB 3.29Å; F494-S498 WeakPolarHBondContact O-CB 3.22Å; F494-S498 PolarHBondContact O-N 3.43Å; F494-S498 PolarHBondContact O-OG 3.09Å
495	Q	89.8	Confident	88.2	Confident	116 Å²	116	110.4 Å²	110.4	54%	0.542	55%	0.551	S	S	.	*	H	α-helix	trans	-61.9	-48.9	173.8	-97.9	161.3	-32	0	0	111.7	T491 R492 T497 S498 E499	T491-Q495 PolarHBondContact O-N 2.86Å; R492-Q495 PolarHBondContact O-N 3.07Å; Q495-T497 PolarHBondContact O-N 2.82Å; Q495-S498 WeakPolarHBondContact CA-OG 3.38Å; Q495-S498 PolarHBondContact O-N 2.95Å; Q495-S498 PolarHBondContact O-OG 3.44Å; Q495-E499 WeakPolarHBondContact O-CG 3.44Å; Q495-E499 PolarHBondContact O-N 2.95Å
496	Q	90.9	Very high	86.9	Confident	116 Å²	116	113.3 Å²	113.3	54%	0.542	56%	0.556	S	S	.	*	H	α-helix	trans	-59.8	-44.4	176.9	-76.2	-179.5	-24.7	0	0	112.8	R492 C493 S498 E499 L500	R492-Q496 PolarHBondContact O-N 2.79Å; C493-Q496 PolarHBondContact O-N 2.94Å; Q496-S498 VanDerWaalsContact C-N 3.34Å; Q496-E499 PolarHBondContact O-N 3.12Å; Q496-L500 WeakPolarHBondContact O-CG 3.46Å; Q496-L500 PolarHBondContact O-N 2.97Å
497	T	88.6	Confident	85.4	Confident	76 Å²	76	116.6 Å²	116.6	47%	0.466	57%	0.573	S	S	.	*	H	α-helix	trans	-65.3	-38.7	176.8	49.8	0	0	0	0	111.4	C493 F494 Q495 L500 L501	C493-T497 WeakPolarHBondContact O-CB 3.4Å; C493-T497 WeakPolarHBondContact O-CG2 3.41Å; C493-T497 PolarHBondContact O-N 3.47Å; C493-T497 PolarHBondContact O-OG1 2.86Å; F494-T497 WeakPolarHBondContact CA-OG1 3.35Å; F494-T497 PolarHBondContact O-N 2.92Å; F494-T497 PolarHBondContact O-OG1 3.39Å; Q495-T497 PolarHBondContact O-N 2.82Å; T497-L500 PolarHBondContact O-N 3.36Å; T497-L501 VanDerWaalsContact O-CB 3.27Å; T497-L501 WeakPolarHBondContact O-CB 3.19Å; T497-L501 PolarHBondContact O-N 3.43Å
498	S	86.4	Confident	83.8	Confident	65 Å²	65	121.3 Å²	121.3	46%	0.455	58%	0.582	S	S	.	*	H	α-helix	trans	-64.3	-39	174.6	76.6	0	0	0	0	112.8	F494 Q495 Q496 L501 F502	F494-S498 VanDerWaalsContact O-CB 3.29Å; F494-S498 WeakPolarHBondContact O-CB 3.22Å; F494-S498 PolarHBondContact O-N 3.43Å; F494-S498 PolarHBondContact O-OG 3.09Å; Q495-S498 WeakPolarHBondContact CA-OG 3.38Å; Q495-S498 PolarHBondContact O-N 2.95Å; Q495-S498 PolarHBondContact O-OG 3.44Å; Q496-S498 VanDerWaalsContact C-N 3.34Å; S498-L501 PolarHBondContact O-N 3.19Å; S498-F502 WeakPolarHBondContact O-CB 3.27Å; S498-F502 PolarHBondContact O-N 3.33Å
499	E	84.7	Confident	82.1	Confident	130 Å²	130	122 Å²	122	61%	0.607	59%	0.586	S	S	*	*	H	α-helix	trans	-65.1	-46.5	175.4	-75.8	-175.4	170.7	0	0	111.3	Q495 Q496 L501 F502 E503	Q495-E499 WeakPolarHBondContact O-CG 3.44Å; Q495-E499 PolarHBondContact O-N 2.95Å; Q496-E499 PolarHBondContact O-N 3.12Å; E499-L501 VanDerWaalsContact C-N 3.32Å; E499-L501 PolarHBondContact O-N 3.3Å; E499-F502 WeakPolarHBondContact O-CB 3.46Å; E499-F502 PolarHBondContact O-N 3.05Å; E499-E503 PolarHBondContact O-N 3.26Å
500	L	83.8	Confident	80.2	Confident	104 Å²	104	122.4 Å²	122.4	55%	0.545	60%	0.598	S	S	.	*	H	α-helix	trans	-62.5	-38.6	176	-70.7	172	0	0	0	112	Q496 T497 E503 V504	Q496-L500 WeakPolarHBondContact O-CG 3.46Å; Q496-L500 PolarHBondContact O-N 2.97Å; T497-L500 PolarHBondContact O-N 3.36Å; L500-E503 PolarHBondContact O-N 3.17Å; L500-V504 VanDerWaalsContact O-CG2 3.32Å; L500-V504 WeakPolarHBondContact O-CG2 3.24Å; L500-V504 PolarHBondContact O-N 3.03Å
501	L	81.9	Confident	78.1	Confident	111 Å²	111	125.3 Å²	125.3	58%	0.581	61%	0.609	S	S	*	*	H	α-helix	trans	-69.9	-35.8	178	-147.3	148.6	0	0	0	111.1	T497 S498 E499 V504 L505	T497-L501 VanDerWaalsContact O-CB 3.27Å; T497-L501 WeakPolarHBondContact O-CB 3.19Å; T497-L501 PolarHBondContact O-N 3.43Å; S498-L501 PolarHBondContact O-N 3.19Å; E499-L501 VanDerWaalsContact C-N 3.32Å; E499-L501 PolarHBondContact O-N 3.3Å; L501-V504 PolarHBondContact O-N 3.08Å; L501-L505 HydrophobicContact CD2-CD1 3.73Å; L501-L505 HydrophobicContact CD2-CG 4.19Å; L501-L505 WeakPolarHBondContact O-CB 3.46Å; L501-L505 WeakPolarHBondContact O-CG 3.05Å; L501-L505 PolarHBondContact O-N 3.39Å
502	F	80.5	Confident	76.2	Confident	139 Å²	139	129.4 Å²	129.4	61%	0.61	63%	0.627	S	S	*	*	H	α-helix	trans	-63.7	-43.3	170.9	-173.2	-95.1	0	0	0	111.8	S498 E499 L505 R506	S498-F502 WeakPolarHBondContact O-CB 3.27Å; S498-F502 PolarHBondContact O-N 3.33Å; E499-F502 WeakPolarHBondContact O-CB 3.46Å; E499-F502 PolarHBondContact O-N 3.05Å; F502-L505 PolarHBondContact O-N 3.46Å; F502-R506 VanDerWaalsContact O-CB 3.32Å; F502-R506 WeakPolarHBondContact O-CB 3.15Å; F502-R506 PolarHBondContact O-N 3.14Å
503	E	80	Confident	73.8	Confident	130 Å²	130	135.6 Å²	135.6	61%	0.607	65%	0.65	S	S	*	*	H	α-helix	trans	-61.4	-44.3	173.7	-79.4	-173.3	155.7	0	0	112.4	E499 L500 R506 H507	E499-E503 PolarHBondContact O-N 3.26Å; L500-E503 PolarHBondContact O-N 3.17Å; E503-R506 PolarHBondContact O-N 3.28Å; E503-H507 WeakPolarHBondContact O-CB 3.33Å; E503-H507 PolarHBondContact O-N 2.78Å
504	V	78.4	Confident	72.9	Confident	97 Å²	97	139.2 Å²	139.2	59%	0.588	66%	0.661	S	S	*	*	H	α-helix	trans	-65.6	-41.9	178.1	170.7	0	0	0	0	111.8	L500 L501 R506 H507 R508	L500-V504 VanDerWaalsContact O-CG2 3.32Å; L500-V504 WeakPolarHBondContact O-CG2 3.24Å; L500-V504 PolarHBondContact O-N 3.03Å; L501-V504 PolarHBondContact O-N 3.08Å; V504-R506 VanDerWaalsContact C-N 3.35Å; V504-H507 PolarHBondContact O-N 3.16Å; V504-R508 WeakPolarHBondContact O-CB 3.24Å; V504-R508 PolarHBondContact O-N 3.2Å
505	L	72.1	Confident	72	Confident	105 Å²	105	138.8 Å²	138.8	55%	0.55	66%	0.662	S	S	.	*	H	α-helix	trans	-63.7	-40.4	175.3	-78.8	170.6	0	0	0	111.9	L501 F502 H507 R508 N509	L501-L505 HydrophobicContact CD2-CD1 3.73Å; L501-L505 HydrophobicContact CD2-CG 4.19Å; L501-L505 WeakPolarHBondContact O-CB 3.46Å; L501-L505 WeakPolarHBondContact O-CG 3.05Å; L501-L505 PolarHBondContact O-N 3.39Å; F502-L505 PolarHBondContact O-N 3.46Å; L505-H507 VanDerWaalsContact C-N 3.28Å; L505-H507 PolarHBondContact O-N 3.1Å; L505-R508 PolarHBondContact O-N 3.36Å; L505-N509 PolarHBondContact O-N 3.03Å; L505-N509 VanDerWaalsContact O-N 3.16Å
506	R	66.9	Low	71	Confident	189 Å²	189	140.1 Å²	140.1	71%	0.713	67%	0.669	S	S	*	*	H	α-helix	trans	-64	-34.1	174.3	-169.5	176.3	-170.6	167.7	4	112.2	F502 E503 V504	F502-R506 VanDerWaalsContact O-CB 3.32Å; F502-R506 WeakPolarHBondContact O-CB 3.15Å; F502-R506 PolarHBondContact O-N 3.14Å; E503-R506 PolarHBondContact O-N 3.28Å; V504-R506 VanDerWaalsContact C-N 3.35Å
507	H	65.4	Low	69.8	Low	171 Å²	171	141.5 Å²	141.5	79%	0.792	68%	0.676	S	S	*	*	H	α-helix	trans	-76	-27.8	177.2	-147	18.4	0	0	0	112.8	E503 V504 L505	E503-H507 WeakPolarHBondContact O-CB 3.33Å; E503-H507 PolarHBondContact O-N 2.78Å; V504-H507 PolarHBondContact O-N 3.16Å; L505-H507 VanDerWaalsContact C-N 3.28Å; L505-H507 PolarHBondContact O-N 3.1Å
508	R	60.2	Low	68.6	Low	213 Å²	213	145.6 Å²	145.6	80%	0.804	69%	0.689	S	S	*	*	H	α-helix	trans	-84.3	-19.9	-179.5	-156.2	178.1	-174.4	-178.4	2	114.2	V504 L505	V504-R508 WeakPolarHBondContact O-CB 3.24Å; V504-R508 PolarHBondContact O-N 3.2Å; L505-R508 PolarHBondContact O-N 3.36Å
509	N	57.6	Low	67.4	Low	115 Å²	115	151 Å²	151	62%	0.615	71%	0.705	S	S	*	*			trans	-124	87.6	175.3	-110.3	-2.7	0	0	0	111	L505 E511	L505-N509 PolarHBondContact O-N 3.03Å; L505-N509 VanDerWaalsContact O-N 3.16Å; N509-E511 PolarHBondContact O-N 2.99Å
510	P	54.5	Low	66.2	Low	119 Å²	119	152.5 Å²	152.5	77%	0.773	71%	0.712	S	S	*	*			trans	-78	-0.5	176.4	30.3	-32.8	0	0	0	114.2
511	E	51.3	Low	64.9	Low	168 Å²	168	156.2 Å²	156.2	79%	0.785	73%	0.725	S	S	*	*			trans	-120.8	88.9	175.4	-67.9	-166.6	175.4	0	0	110.4	N509	N509-E511 PolarHBondContact O-N 2.99Å
512	I	52	Low	63.4	Low	158 Å²	158	160 Å²	160	81%	0.81	74%	0.737	S	S	*	*			trans	-163.8	103.3	137.6	-81.4	134.3	0	0	0	103.1
513	R	42.4	Very low	61.9	Low	316 Å²	316	161.9 Å²	161.9	100%	1.192	75%	0.748	S	S	*	*			trans	-107.8	0	168.2	-165.7	-175.7	-152.8	174.1	7.8	108.4

Retrieved 513 of 513 residues in 618 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).