A0A087XPV8_POEFO Loading...

Y+L amino acid transporter 2

AlphaFold DB , UniProt , Accession A0A087XPV8, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 501 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	S	28.2	Very low	27.7	Very low	173 Å²	173	135.1 Å²	135.1	100%	1.21	83%	0.83	S	S	*	*				0	149	0	-65.1	0	0	0	0	110.2
2	P	45	Very low	27.5	Very low	108 Å²	108	129.2 Å²	129.2	70%	0.701	82%	0.816	S	S	*	*			cis	-127.3	169.3	-12	30.6	-8.4	0	0	0	109.4
3	K	26.8	Very low	27.5	Very low	179 Å²	179	127.7 Å²	127.7	78%	0.778	81%	0.812	S	S	*	*				-168.8	122.9	60	-84.5	-177.8	176	175.6	0	107.4
4	T	27.6	Very low	27.5	Very low	113 Å²	113	128.3 Å²	128.3	69%	0.693	81%	0.806	S	S	*	*				60	127.4	92.7	25.5	0	0	0	0	112.5
5	N	26	Very low	27.6	Very low	127 Å²	127	130.9 Å²	130.9	68%	0.679	80%	0.801	S	S	*	*				-171.3	134.1	53.6	-104.3	-11	0	0	0	109.2
6	I	26.6	Very low	27.7	Very low	140 Å²	140	131.4 Å²	131.4	72%	0.718	80%	0.796	S	S	*	*				92.6	120.3	93.4	-66.9	176.2	0	0	0	114.3
7	M	25.7	Very low	27.7	Very low	177 Å²	177	132.6 Å²	132.6	87%	0.872	80%	0.797	S	S	*	*			trans	-8	141.8	150.6	-61.9	171.4	-179	0	0	118.7
8	A	25.4	Very low	27.6	Very low	103 Å²	103	129.2 Å²	129.2	85%	0.851	79%	0.794	S	S	*	*				176	140.3	102.1	0	0	0	0	0	112.5
9	G	23.6	Very low	27.8	Very low	85 Å²	85	129.1 Å²	129.1	88%	0.876	80%	0.799	S	S	*	*			trans	107	126.9	141.1	0	0	0	0	0	118
10	G	25	Very low	27.8	Very low	77 Å²	77	127.2 Å²	127.2	79%	0.794	80%	0.796	S	S	*	*			trans	122.9	89.8	141.2	0	0	0	0	0	117.5
11	E	25.1	Very low	27.8	Very low	204 Å²	204	126 Å²	126	95%	0.953	79%	0.793	S	S	*	*			trans	-0.7	149.7	141.2	-64.7	173.8	150.4	0	0	121.2
12	G	25.4	Very low	27.9	Very low	64 Å²	64	127.6 Å²	127.6	66%	0.66	78%	0.781	S	S	*	*			trans	103.1	96.5	147.8	0	0	0	0	0	115
13	S	26.9	Very low	27.1	Very low	110 Å²	110	127.3 Å²	127.3	77%	0.769	78%	0.781	S	S	*	*				58.4	102.4	103	67.5	0	0	0	0	114.8
14	D	28.2	Very low	27.3	Very low	136 Å²	136	124.1 Å²	124.1	73%	0.727	78%	0.782	S	S	*	*				164.2	133.6	107.6	-100.4	-31.7	0	0	0	112.5
15	K	28.4	Very low	27.3	Very low	167 Å²	167	123.4 Å²	123.4	73%	0.726	78%	0.781	S	S	*	*			trans	50.8	120.7	137.9	-69	-179.1	-179.2	171.7	0	122.2
16	L	29.3	Very low	27.5	Very low	139 Å²	139	126 Å²	126	73%	0.728	79%	0.789	S	S	*	*				69.1	127.8	124.3	-77.1	147.7	0	0	0	120.5
17	D	27.3	Very low	27.6	Very low	153 Å²	153	126.8 Å²	126.8	82%	0.818	79%	0.79	S	S	*	*			trans	73.8	119.7	150.3	-63.5	-18.5	0	0	0	119.8
18	G	26.7	Very low	27.8	Very low	71 Å²	71	125.6 Å²	125.6	73%	0.732	79%	0.787	S	S	*	*			trans	139.2	99	144.8	0	0	0	0	0	116.7
19	S	30.7	Very low	28.1	Very low	127 Å²	127	128.3 Å²	128.3	89%	0.888	78%	0.782	S	S	*	*			trans	79.1	105.3	150.5	110.6	0	0	0	0	117.4
20	A	27.9	Very low	28.6	Very low	91 Å²	91	128.7 Å²	128.7	75%	0.752	77%	0.771	S	S	*	*			trans	-131.8	99.8	151.9	0	0	0	0	0	107.8
21	S	28.2	Very low	28.9	Very low	103 Å²	103	132.9 Å²	132.9	72%	0.72	77%	0.767	S	S	*	*			trans	28.6	105.2	141.6	44.5	0	0	0	0	117.4	S23	S21-S23 PolarHBondContact O-N 2.97Å
22	Q	30.7	Very low	29.4	Very low	205 Å²	205	132 Å²	132	96%	0.958	76%	0.763	S	S	*	*			trans	-52.8	102.6	152.6	-78.7	174.7	-20.4	0	0	109.3
23	S	27.8	Very low	29.8	Very low	102 Å²	102	135 Å²	135	71%	0.713	76%	0.76	S	S	*	*			trans	-102.6	106.1	155.3	53.8	0	0	0	0	106.7	S21 S25	S21-S23 PolarHBondContact O-N 2.97Å; S23-S25 PolarHBondContact O-N 2.88Å
24	S	31.3	Very low	30.1	Very low	112 Å²	112	139.1 Å²	139.1	78%	0.783	77%	0.769	S	S	*	*			trans	-58.6	93.9	173.1	50.3	0	0	0	0	110	H26	S24-H26 PolarHBondContact O-N 3.1Å
25	S	27.2	Very low	30.9	Very low	98 Å²	98	141.3 Å²	141.3	69%	0.685	77%	0.772	S	S	*	*			trans	-86.2	94.7	158.9	46	0	0	0	0	107.2	S23 Q27	S23-S25 PolarHBondContact O-N 2.88Å; S25-Q27 PolarHBondContact O-N 3.3Å
26	H	29.1	Very low	32.3	Very low	183 Å²	183	137.5 Å²	137.5	85%	0.847	76%	0.759	S	S	*	*			trans	-58.4	95.6	155.9	-90	-72	0	0	0	106.6	S24 D28	S24-H26 PolarHBondContact O-N 3.1Å; H26-D28 PolarHBondContact O-N 3.49Å
27	Q	29.6	Very low	34.1	Very low	156 Å²	156	138.3 Å²	138.3	73%	0.729	76%	0.757	S	S	*	*			trans	-65.6	96.5	160.5	-82.6	-178.6	-17.8	0	0	106	S25 H29	S25-Q27 PolarHBondContact O-N 3.3Å; Q27-H29 PolarHBondContact O-N 3.37Å
28	D	29.2	Very low	36.4	Very low	151 Å²	151	137.1 Å²	137.1	81%	0.807	74%	0.744	S	S	*	*			trans	-61.8	94.3	164.5	-151.2	8.1	0	0	0	105.8	H26 S30	H26-D28 PolarHBondContact O-N 3.49Å; D28-S30 PolarHBondContact O-N 3.07Å
29	H	32.7	Very low	38.9	Very low	161 Å²	161	139.6 Å²	139.6	75%	0.745	74%	0.737	S	S	*	*			trans	-65.2	81.8	165.8	-88.5	-66	0	0	0	106.4	Q27 K31	Q27-H29 PolarHBondContact O-N 3.37Å; H29-K31 PolarHBondContact O-N 3.23Å
30	S	34.1	Very low	41.3	Very low	93 Å²	93	134.6 Å²	134.6	65%	0.65	70%	0.7	S	S	*	*			trans	-52.2	109.1	159.2	47.4	0	0	0	0	105.7	D28 E32	D28-S30 PolarHBondContact O-N 3.07Å; S30-E32 VanDerWaalsContact C-N 3.26Å; S30-E32 PolarHBondContact O-N 3.41Å
31	K	32.2	Very low	44.1	Very low	164 Å²	164	132 Å²	132	71%	0.713	68%	0.676	S	S	*	*			trans	-55.7	98.4	169.2	-76.6	178	176.1	179	0	106	H29 H33	H29-K31 PolarHBondContact O-N 3.23Å; K31-H33 PolarHBondContact O-CD2 3.04Å; K31-H33 VanDerWaalsContact O-CD2 3.23Å; K31-H33 PolarHBondContact O-N 3.31Å
32	E	33.7	Very low	46.9	Very low	187 Å²	187	129.3 Å²	129.3	87%	0.874	65%	0.654	S	S	*	*			trans	-64.4	91.1	168.2	-82.1	-166	154.8	0	0	106.6	S30 M34	S30-E32 VanDerWaalsContact C-N 3.26Å; S30-E32 PolarHBondContact O-N 3.41Å; E32-M34 PolarHBondContact O-N 2.81Å; E32-M34 VanDerWaalsContact O-N 3.16Å
33	H	33.8	Very low	49.5	Very low	127 Å²	127	126.1 Å²	126.1	59%	0.588	64%	0.642	S	S	*	*			trans	-63.7	117.4	171.3	-73.4	-79	0	0	0	107.5	K31 K35	K31-H33 PolarHBondContact O-CD2 3.04Å; K31-H33 VanDerWaalsContact O-CD2 3.23Å; K31-H33 PolarHBondContact O-N 3.31Å; H33-K35 VanDerWaalsContact C-N 3.35Å; H33-K35 PolarHBondContact O-N 2.81Å
34	M	35.1	Very low	52	Low	196 Å²	196	125.5 Å²	125.5	97%	0.966	63%	0.631	S	S	*	*			trans	-63.6	95.3	174.4	-157.5	-173.2	-50.8	0	0	108.2	E32	E32-M34 PolarHBondContact O-N 2.81Å; E32-M34 VanDerWaalsContact O-N 3.16Å
35	K	44.9	Very low	54.5	Low	181 Å²	181	120.2 Å²	120.2	79%	0.787	59%	0.594	S	S	*	*	P	Polyproline II helix	trans	-89.9	140	176.6	-71.1	-179.1	-178.8	177.6	0	109.5	H33 K37	H33-K35 VanDerWaalsContact C-N 3.35Å; H33-K35 PolarHBondContact O-N 2.81Å; K35-K37 PolarHBondContact O-N 2.93Å
36	L	57	Low	57.4	Low	88 Å²	88	116.5 Å²	116.5	46%	0.461	57%	0.567	S	S	.	*	P	Polyproline II helix	trans	-56.3	137.1	171	-68.4	172.6	0	0	0	109.9	K38 E253 E254	L36-K38 PolarHBondContact O-N 2.92Å; L36-E253 HydrophobicContact CD1-CB 4.18Å; L36-E254 HydrophobicContact CB-CG 4.15Å; L36-E254 HydrophobicContact CD1-CG 4.23Å
37	K	66.7	Low	59.9	Low	156 Å²	156	110.2 Å²	110.2	68%	0.678	54%	0.544	S	S	*	.	P	Polyproline II helix	trans	-71.9	129.5	-179.3	-70.7	-174	177.8	-180	0	109.8	K35 E39	K35-K37 PolarHBondContact O-N 2.93Å; K37-E39 HydrophobicContact CB-CG 3.86Å; K37-E39 WeakPolarHBondContact CD-OE1 3.48Å; K37-E39 PolarHBondContact O-N 3.46Å
38	K	75.8	Confident	62.3	Low	128 Å²	128	105.1 Å²	105.1	56%	0.557	52%	0.521	S	S	*	.			trans	-78	84.5	175.9	-67.1	-176.9	179.4	-176.3	0	110.8	L36 E253 E254 K256	L36-K38 PolarHBondContact O-N 2.92Å; K38-E253 WeakPolarHBondContact CG-O 3.44Å; K38-E254 CarbonylContact C-O 3.5Å; K38-E254 VanDerWaalsContact CA-O 3.29Å; K38-E254 WeakPolarHBondContact CA-O 3.46Å; K38-K256 HydrophobicContact CB-CG 4.34Å; K38-K256 WeakPolarHBondContact O-CE 2.95Å; K38-K256 VanDerWaalsContact O-CG 3.24Å; K38-K256 WeakPolarHBondContact O-CG 3.46Å
39	E	79.7	Confident	65	Low	123 Å²	123	97.9 Å²	97.9	58%	0.575	48%	0.483	S	S	*	.			trans	-106.2	-21.7	-174.5	-65.2	-172.6	171.3	0	0	113.6	K37 S41 E254	K37-E39 HydrophobicContact CB-CG 3.86Å; K37-E39 WeakPolarHBondContact CD-OE1 3.48Å; K37-E39 PolarHBondContact O-N 3.46Å; E39-S41 PolarHBondContact O-N 3.38Å; E39-E254 PolarHBondContact N-O 3.12Å
40	I	80	Confident	67.5	Low	22 Å²	22	91.2 Å²	91.2	11%	0.113	45%	0.453	C	S	.	.	B	Isolated β-bridge	trans	-76.4	112.9	-173.8	-55.5	177.5	0	0	0	110.3	N44 V251 E254 I255 K256	I40-N44 HydrophobicContact CG2-CB 3.97Å; I40-V251 HydrophobicContact CD1-CB 3.97Å; I40-V251 HydrophobicContact CD1-CG2 3.79Å; I40-E254 HydrophobicContact CD1-CB 3.79Å; I40-E254 HydrophobicContact CG1-CB 4.14Å; I40-E254 PolarHBondContact N-O 3.21Å; I40-I255 HydrophobicContact CB-CG1 4.21Å; I40-I255 HydrophobicContact CG2-CG1 4.21Å; I40-K256 WeakPolarHBondContact O-CB 3.13Å; I40-K256 PolarHBondContact O-N 2.98Å
41	S	88.2	Confident	69.7	Low	35 Å²	35	86.9 Å²	86.9	25%	0.245	42%	0.424	C	S	.	.			trans	-80.9	170.9	175	79.9	0	0	0	0	112.2	E39 L43 N44 G45	E39-S41 PolarHBondContact O-N 3.38Å; S41-L43 PolarHBondContact O-N 3.34Å; S41-N44 PolarHBondContact O-N 3.23Å; S41-N44 PolarHBondContact OG-N 3.06Å; S41-N44 PolarHBondContact OG-OD1 3.09Å; S41-N44 VanDerWaalsContact OG-OD1 3.13Å; S41-G45 PolarHBondContact O-N 3.32Å
42	L	86.6	Confident	72	Confident	48 Å²	48	81.4 Å²	81.4	25%	0.251	40%	0.402	S	S	.	.	H	α-helix	trans	-57.4	-46.3	175	177.6	65.4	0	0	0	112.4	N44 G45 V46 N261 L264 S265	L42-N44 VanDerWaalsContact C-N 3.33Å; L42-N44 PolarHBondContact O-N 3.43Å; L42-G45 PolarHBondContact O-N 3.15Å; L42-G45 VanDerWaalsContact O-N 3.16Å; L42-V46 WeakPolarHBondContact O-CG2 3.16Å; L42-V46 PolarHBondContact O-N 3.44Å; L42-N261 HydrophobicContact CD1-CB 4.3Å; L42-L264 HydrophobicContact CD1-CB 3.62Å; L42-L264 HydrophobicContact CD2-CD1 4.5Å; L42-S265 WeakPolarHBondContact CD1-OG 3.34Å
43	L	84.1	Confident	74.5	Confident	137 Å²	137	72.7 Å²	72.7	72%	0.717	36%	0.361	S	S	*	.	H	α-helix	trans	-66.3	-38.3	179.5	-70.1	174.6	0	0	0	111.5	S41 G45 V46 S47	S41-L43 PolarHBondContact O-N 3.34Å; L43-G45 VanDerWaalsContact C-N 3.28Å; L43-G45 PolarHBondContact O-N 3.29Å; L43-V46 PolarHBondContact O-N 3.34Å; L43-S47 WeakPolarHBondContact O-CB 3.1Å; L43-S47 PolarHBondContact O-N 3.28Å
44	N	82.1	Confident	76.9	Confident	89 Å²	89	66.6 Å²	66.6	48%	0.476	33%	0.333	S	S	.	.	H	α-helix	trans	-62.9	-39.9	173.6	-61.8	3.7	0	0	0	110.2	I40 S41 L42 S47 L48	I40-N44 HydrophobicContact CG2-CB 3.97Å; S41-N44 PolarHBondContact O-N 3.23Å; S41-N44 PolarHBondContact OG-N 3.06Å; S41-N44 PolarHBondContact OG-OD1 3.09Å; S41-N44 VanDerWaalsContact OG-OD1 3.13Å; L42-N44 VanDerWaalsContact C-N 3.33Å; L42-N44 PolarHBondContact O-N 3.43Å; N44-S47 PolarHBondContact O-N 3.44Å; N44-L48 VanDerWaalsContact O-CB 3.24Å; N44-L48 WeakPolarHBondContact O-CB 3.42Å; N44-L48 PolarHBondContact O-N 3.28Å
45	G	83.3	Confident	79	Confident	1 Å²	1	57.8 Å²	57.8	1%	0.01	29%	0.292	C	S	.	.	H	α-helix	trans	-62.2	-47.5	176	0	0	0	0	0	113.1	S41 L42 L43 L48 I49	S41-G45 PolarHBondContact O-N 3.32Å; L42-G45 PolarHBondContact O-N 3.15Å; L42-G45 VanDerWaalsContact O-N 3.16Å; L43-G45 VanDerWaalsContact C-N 3.28Å; L43-G45 PolarHBondContact O-N 3.29Å; G45-L48 PolarHBondContact O-N 2.84Å; G45-I49 PolarHBondContact O-N 2.98Å
46	V	87.2	Confident	80.7	Confident	21 Å²	21	49.5 Å²	49.5	13%	0.127	26%	0.257	C	S	.	.	H	α-helix	trans	-60.3	-48.5	174.9	174.1	0	0	0	0	110.8	L42 L43 L48 I49 V50 I268	L42-V46 WeakPolarHBondContact O-CG2 3.16Å; L42-V46 PolarHBondContact O-N 3.44Å; L43-V46 PolarHBondContact O-N 3.34Å; V46-L48 VanDerWaalsContact C-N 3.28Å; V46-L48 PolarHBondContact O-N 3.29Å; V46-I49 PolarHBondContact O-N 2.94Å; V46-V50 HydrophobicContact CG1-CG2 4.19Å; V46-V50 WeakPolarHBondContact O-CB 3.41Å; V46-V50 VanDerWaalsContact O-CG2 3.31Å; V46-V50 WeakPolarHBondContact O-CG2 3.26Å; V46-V50 PolarHBondContact O-N 3.17Å; V46-I268 HydrophobicContact CG1-CG2 4.05Å; V46-I268 HydrophobicContact CG2-CB 4.11Å; V46-I268 HydrophobicContact CG2-CD1 4.35Å; V46-I268 HydrophobicContact CG2-CG2 4.12Å
47	S	82.6	Confident	82.2	Confident	51 Å²	51	45.5 Å²	45.5	36%	0.357	24%	0.237	S	C	.	.	H	α-helix	trans	-60.2	-39.1	178.8	-171.9	0	0	0	0	111.9	L43 N44 G51	L43-S47 WeakPolarHBondContact O-CB 3.1Å; L43-S47 PolarHBondContact O-N 3.28Å; N44-S47 PolarHBondContact O-N 3.44Å; S47-G51 WeakPolarHBondContact O-CA 3.42Å; S47-G51 PolarHBondContact O-N 2.88Å
48	L	80.5	Confident	83.4	Confident	48 Å²	48	38.1 Å²	38.1	25%	0.251	21%	0.205	S	C	.	.	H	α-helix	trans	-66.6	-45.3	177.7	-168.6	160.5	0	0	0	111.6	N44 G45 V46 N52 T247 L248	N44-L48 VanDerWaalsContact O-CB 3.24Å; N44-L48 WeakPolarHBondContact O-CB 3.42Å; N44-L48 PolarHBondContact O-N 3.28Å; G45-L48 PolarHBondContact O-N 2.84Å; V46-L48 VanDerWaalsContact C-N 3.28Å; V46-L48 PolarHBondContact O-N 3.29Å; L48-N52 WeakPolarHBondContact CD2-ND2 3.48Å; L48-N52 WeakPolarHBondContact O-CB 3.37Å; L48-N52 VanDerWaalsContact O-CG 3.31Å; L48-N52 PolarHBondContact O-N 3.36Å; L48-T247 HydrophobicContact CD2-CG2 3.86Å; L48-L248 HydrophobicContact CB-CD2 4.21Å; L48-L248 HydrophobicContact CD1-CD2 4Å; L48-L248 HydrophobicContact CD2-CD2 3.83Å; L48-L248 HydrophobicContact CD2-CG 4.32Å; L48-L248 HydrophobicContact CG-CD2 4.24Å
49	I	85.1	Confident	84.1	Confident	0 Å²	0	32.1 Å²	32.1	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-63.9	-53.1	176.4	-66.1	172.1	0	0	0	110.6	G45 V46 G51 N52 M53 W245 L248 I266 S269	G45-I49 PolarHBondContact O-N 2.98Å; V46-I49 PolarHBondContact O-N 2.94Å; I49-G51 VanDerWaalsContact C-N 3.27Å; I49-G51 PolarHBondContact O-N 2.84Å; I49-N52 PolarHBondContact O-N 3.3Å; I49-N52 VanDerWaalsContact O-N 3.15Å; I49-M53 HydrophobicContact CG2-CG 4.03Å; I49-M53 HydrophobicContact CG2-SD 3.44Å; I49-M53 WeakPolarHBondContact CG2-SD 3.24Å; I49-M53 WeakPolarHBondContact O-CB 3.29Å; I49-M53 WeakPolarHBondContact O-CG 3.48Å; I49-M53 PolarHBondContact O-N 3.44Å; I49-W245 HydrophobicContact CG2-CB 4.43Å; I49-L248 HydrophobicContact CD1-CD1 3.36Å; I49-L248 HydrophobicContact CD1-CG 3.95Å; I49-L248 HydrophobicContact CG1-CD1 3.61Å; I49-L248 HydrophobicContact CG1-CG 3.69Å; I49-I266 HydrophobicContact CD1-CB 4.48Å; I49-I266 HydrophobicContact CD1-CG1 3.66Å; I49-S269 WeakPolarHBondContact CD1-OG 3.21Å; I49-S269 VanDerWaalsContact CG2-OG 3.23Å; I49-S269 WeakPolarHBondContact CG2-OG 3.35Å
50	V	85.6	Confident	84.6	Confident	20 Å²	20	27.1 Å²	27.1	12%	0.121	16%	0.157	C	C	.	.	H	α-helix	trans	-59.6	-43.4	-178.6	174.1	0	0	0	0	110	V46 I54 V273	V46-V50 HydrophobicContact CG1-CG2 4.19Å; V46-V50 WeakPolarHBondContact O-CB 3.41Å; V46-V50 VanDerWaalsContact O-CG2 3.31Å; V46-V50 WeakPolarHBondContact O-CG2 3.26Å; V46-V50 PolarHBondContact O-N 3.17Å; V50-I54 HydrophobicContact CG1-CD1 3.55Å; V50-I54 HydrophobicContact CG1-CG1 4.2Å; V50-I54 WeakPolarHBondContact O-CB 3.28Å; V50-I54 VanDerWaalsContact O-CG1 3.28Å; V50-I54 WeakPolarHBondContact O-CG1 3.35Å; V50-I54 PolarHBondContact O-N 3.21Å; V50-V273 HydrophobicContact CG1-CG2 4.44Å; V50-V273 HydrophobicContact CG2-CG2 4.21Å
51	G	80	Confident	85.3	Confident	3 Å²	3	26 Å²	26	3%	0.031	15%	0.151	C	C	.	.	H	α-helix	trans	-65.6	-34.5	177.5	0	0	0	0	0	113.4	S47 I49 K194	S47-G51 WeakPolarHBondContact O-CA 3.42Å; S47-G51 PolarHBondContact O-N 2.88Å; I49-G51 VanDerWaalsContact C-N 3.27Å; I49-G51 PolarHBondContact O-N 2.84Å; G51-K194 WeakPolarHBondContact O-CE 3.42Å; G51-K194 PolarHBondContact O-NZ 2.92Å
52	N	79.5	Confident	85.7	Confident	48 Å²	48	24.4 Å²	24.4	26%	0.257	14%	0.14	S	C	.	.	H	α-helix	trans	-82.5	-38.8	178.5	-74.2	-7.1	0	0	0	112.5	L48 I49 T247	L48-N52 WeakPolarHBondContact CD2-ND2 3.48Å; L48-N52 WeakPolarHBondContact O-CB 3.37Å; L48-N52 VanDerWaalsContact O-CG 3.31Å; L48-N52 PolarHBondContact O-N 3.36Å; I49-N52 PolarHBondContact O-N 3.3Å; I49-N52 VanDerWaalsContact O-N 3.15Å; N52-T247 WeakPolarHBondContact ND2-CB 3.37Å; N52-T247 VanDerWaalsContact ND2-CG2 3.26Å; N52-T247 WeakPolarHBondContact ND2-CG2 3.49Å; N52-T247 PolarHBondContact ND2-OG1 3.47Å; N52-T247 VanDerWaalsContact ND2-OG1 3.15Å
53	M	85.9	Confident	86.1	Confident	4 Å²	4	23.4 Å²	23.4	2%	0.02	13%	0.134	C	C	.	.	H	α-helix	trans	-67.8	-50.1	178	-70	178.9	77.1	0	0	111.6	I49 G55 Y242 S243 W245 M270 V273 Y277	I49-M53 HydrophobicContact CG2-CG 4.03Å; I49-M53 HydrophobicContact CG2-SD 3.44Å; I49-M53 WeakPolarHBondContact CG2-SD 3.24Å; I49-M53 WeakPolarHBondContact O-CB 3.29Å; I49-M53 WeakPolarHBondContact O-CG 3.48Å; I49-M53 PolarHBondContact O-N 3.44Å; M53-G55 VanDerWaalsContact C-N 3.26Å; M53-G55 PolarHBondContact O-N 2.93Å; M53-Y242 HydrophobicContact CE-CD1 3.73Å; M53-Y242 HydrophobicContact CE-CG 4.46Å; M53-Y242 VanDerWaalsContact CE-O 3.28Å; M53-Y242 WeakPolarHBondContact CE-O 3.26Å; M53-S243 WeakPolarHBondContact CA-O 3.32Å; M53-W245 HydrophobicContact CE-CB 4.43Å; M53-W245 HydrophobicContact CG-CB 4.41Å; M53-W245 HydrophobicContact SD-CB 3.87Å; M53-M270 HydrophobicContact CE-CE 3.6Å; M53-M270 HydrophobicContact CE-SD 3.6Å; M53-M270 HydrophobicContact SD-CE 4.36Å; M53-M270 HydrophobicContact SD-SD 3.54Å; M53-V273 HydrophobicContact CB-CG1 4.22Å; M53-V273 HydrophobicContact CB-CG2 4.27Å; M53-V273 HydrophobicContact CE-CB 4.26Å; M53-V273 HydrophobicContact CE-CG1 3.88Å; M53-V273 HydrophobicContact SD-CB 4.47Å; M53-V273 HydrophobicContact SD-CG1 4.46Å; M53-V273 HydrophobicContact SD-CG2 4.11Å; M53-Y277 VanDerWaalsContact C-OH 3.27Å; M53-Y277 PolarHBondContact O-OH 3.44Å
54	I	85.5	Confident	86.5	Confident	0 Å²	0	16.9 Å²	16.9	0%	0	10%	0.1	C	C	.	.	S	Bend	trans	-70.7	87	177.2	-59.6	-176.5	0	0	0	108	V50 K194 V195 L198 V273 I276 Y277	V50-I54 HydrophobicContact CG1-CD1 3.55Å; V50-I54 HydrophobicContact CG1-CG1 4.2Å; V50-I54 WeakPolarHBondContact O-CB 3.28Å; V50-I54 VanDerWaalsContact O-CG1 3.28Å; V50-I54 WeakPolarHBondContact O-CG1 3.35Å; V50-I54 PolarHBondContact O-N 3.21Å; I54-K194 HydrophobicContact CG2-CD 4.35Å; I54-K194 HydrophobicContact CG2-CG 4.41Å; I54-K194 WeakPolarHBondContact O-CD 3.36Å; I54-K194 WeakPolarHBondContact O-CE 3.48Å; I54-K194 PolarHBondContact O-NZ 2.8Å; I54-V195 HydrophobicContact CD1-CG2 4.42Å; I54-L198 HydrophobicContact CD1-CD1 4.49Å; I54-L198 HydrophobicContact CG2-CD1 3.35Å; I54-V273 HydrophobicContact CD1-CG2 4.35Å; I54-V273 HydrophobicContact CG1-CG1 4.3Å; I54-V273 HydrophobicContact CG1-CG2 4.1Å; I54-I276 HydrophobicContact CD1-CD1 3.89Å; I54-I276 HydrophobicContact CD1-CG2 4.46Å; I54-Y277 WeakPolarHBondContact CA-OH 3.41Å; I54-Y277 HydrophobicContact CG1-CE1 4.13Å
55	G	79.6	Confident	87.2	Confident	10 Å²	10	12.7 Å²	12.7	10%	0.103	8%	0.077	C	C	.	.	S	Bend	trans	-125.2	-146.2	-175.4	0	0	0	0	0	112.7	M53 G57 F59	M53-G55 VanDerWaalsContact C-N 3.26Å; M53-G55 PolarHBondContact O-N 2.93Å; G55-G57 VanDerWaalsContact C-N 3.25Å; G55-G57 PolarHBondContact O-N 3.27Å; G55-F59 WeakPolarHBondContact O-CD2 3.41Å; G55-F59 WeakPolarHBondContact O-CE2 3.42Å
56	S	79.8	Confident	87.8	Confident	8 Å²	8	13 Å²	13	6%	0.056	8%	0.078	C	C	.	.	S	Bend	trans	-69	-24	173.2	57.4	0	0	0	0	112.9	I58 F59 V60 I138 C323	S56-I58 PolarHBondContact O-N 2.72Å; S56-F59 WeakPolarHBondContact O-CB 3.39Å; S56-F59 PolarHBondContact O-N 3.47Å; S56-V60 PolarHBondContact O-N 3.02Å; S56-I138 VanDerWaalsContact OG-CG1 3.27Å; S56-I138 WeakPolarHBondContact OG-CG1 3.21Å; S56-C323 VanDerWaalsContact CB-SG 3.53Å
57	G	87.9	Confident	88.1	Confident	4 Å²	4	15.4 Å²	15.4	4%	0.041	9%	0.09	C	C	.	.	H	α-helix	trans	-54.7	-50.2	-173.9	0	0	0	0	0	113.2	G55 F59 V60 S61 S241	G55-G57 VanDerWaalsContact C-N 3.25Å; G55-G57 PolarHBondContact O-N 3.27Å; G57-F59 PolarHBondContact O-N 3.05Å; G57-V60 PolarHBondContact O-N 3.47Å; G57-S61 VanDerWaalsContact O-CB 3.27Å; G57-S61 WeakPolarHBondContact O-CB 3.34Å; G57-S61 PolarHBondContact O-N 2.94Å; G57-S61 PolarHBondContact O-OG 3.38Å; G57-S61 VanDerWaalsContact O-OG 3.09Å; G57-S241 WeakPolarHBondContact CA-OG 3.4Å; G57-S241 PolarHBondContact O-OG 2.63Å
58	I	91.9	Very high	88.7	Confident	0 Å²	0	15.1 Å²	15.1	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-61.8	-17.4	-177.4	-169.3	54.8	0	0	0	113.3	S56 P62 W79 L198 S241 Y277 T280	S56-I58 PolarHBondContact O-N 2.72Å; I58-P62 WeakPolarHBondContact O-CD 3.41Å; I58-P62 WeakPolarHBondContact O-CG 3.21Å; I58-W79 HydrophobicContact CD1-CH2 3.51Å; I58-W79 HydrophobicContact CD1-CZ2 4.07Å; I58-W79 HydrophobicContact CD1-CZ3 3.93Å; I58-L198 HydrophobicContact CG1-CD2 4.49Å; I58-L198 HydrophobicContact CG2-CD1 4.41Å; I58-L198 HydrophobicContact CG2-CD2 4.18Å; I58-S241 PolarHBondContact N-OG 2.69Å; I58-S241 VanDerWaalsContact N-OG 3.14Å; I58-Y277 HydrophobicContact CB-CD1 4.1Å; I58-Y277 HydrophobicContact CB-CE1 3.74Å; I58-Y277 HydrophobicContact CD1-CD1 3.61Å; I58-Y277 HydrophobicContact CD1-CD2 4.44Å; I58-Y277 HydrophobicContact CD1-CE1 4.14Å; I58-Y277 HydrophobicContact CD1-CG 3.77Å; I58-Y277 HydrophobicContact CG1-CD1 3.69Å; I58-Y277 HydrophobicContact CG1-CE1 3.86Å; I58-Y277 HydrophobicContact CG1-CG 4.37Å; I58-Y277 HydrophobicContact CG2-CE1 4.28Å; I58-T280 HydrophobicContact CD1-CG2 4.42Å; I58-T280 HydrophobicContact CG1-CG2 4.11Å
59	F	90.4	Very high	89.4	Confident	2 Å²	2	12.9 Å²	12.9	1%	0.009	7%	0.07	C	C	.	.	H	α-helix	trans	-92.4	-14.7	179.4	-61.8	-58.4	0	0	0	113.1	G55 S56 G57 T141 Y145 L198 I201 A300 V319	G55-F59 WeakPolarHBondContact O-CD2 3.41Å; G55-F59 WeakPolarHBondContact O-CE2 3.42Å; S56-F59 WeakPolarHBondContact O-CB 3.39Å; S56-F59 PolarHBondContact O-N 3.47Å; G57-F59 PolarHBondContact O-N 3.05Å; F59-T141 HydrophobicContact CB-CG2 4.39Å; F59-Y145 HydrophobicContact CB-CE1 4.5Å; F59-Y145 HydrophobicContact CB-CE2 3.87Å; F59-Y145 WeakPolarHBondContact CB-OH 3.5Å; F59-Y145 PolarHBondContact O-OH 3.07Å; F59-L198 HydrophobicContact CE1-CD2 3.75Å; F59-L198 HydrophobicContact CZ-CD2 3.71Å; F59-L198 HydrophobicContact CZ-CG 4.17Å; F59-I201 HydrophobicContact CE1-CD1 4.41Å; F59-A300 HydrophobicContact CD1-CB 3.89Å; F59-A300 HydrophobicContact CE1-CB 4.23Å; F59-V319 HydrophobicContact CB-CG1 4.06Å; F59-V319 HydrophobicContact CD1-CG1 4.19Å; F59-V319 HydrophobicContact CD1-CG2 3.74Å; F59-V319 HydrophobicContact CD2-CB 4.41Å; F59-V319 HydrophobicContact CD2-CG1 3.53Å; F59-V319 HydrophobicContact CD2-CG2 4.13Å; F59-V319 HydrophobicContact CE1-CG2 3.51Å; F59-V319 HydrophobicContact CE2-CB 4.43Å; F59-V319 HydrophobicContact CE2-CG1 3.99Å; F59-V319 HydrophobicContact CE2-CG2 3.92Å; F59-V319 HydrophobicContact CG-CG1 3.64Å; F59-V319 HydrophobicContact CG-CG2 4.05Å; F59-V319 HydrophobicContact CZ-CG2 3.61Å
60	V	91.6	Very high	89.8	Confident	18 Å²	18	15.6 Å²	15.6	11%	0.109	9%	0.092	C	C	.	.	H	α-helix	trans	-110.9	-45.3	178	178.8	0	0	0	0	112	S56 G57 K63 T141 V381 F382 I385	S56-V60 PolarHBondContact O-N 3.02Å; G57-V60 PolarHBondContact O-N 3.47Å; V60-K63 PolarHBondContact O-N 3.44Å; V60-T141 HydrophobicContact CG2-CG2 3.5Å; V60-T141 WeakPolarHBondContact CG2-OG1 3.35Å; V60-V381 HydrophobicContact CG1-CG1 4.2Å; V60-F382 HydrophobicContact CG1-CE1 4.13Å; V60-F382 HydrophobicContact CG1-CZ 4.36Å; V60-I385 HydrophobicContact CG1-CD1 4.03Å
61	S	94.6	Very high	90.2	Very high	0 Å²	0	15 Å²	15	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-58.5	-32.7	-173.1	-65.4	0	0	0	0	115.5	G57 K63 G64 V65 S237 S241	G57-S61 VanDerWaalsContact O-CB 3.27Å; G57-S61 WeakPolarHBondContact O-CB 3.34Å; G57-S61 PolarHBondContact O-N 2.94Å; G57-S61 PolarHBondContact O-OG 3.38Å; G57-S61 VanDerWaalsContact O-OG 3.09Å; S61-K63 VanDerWaalsContact C-N 3.27Å; S61-K63 PolarHBondContact O-N 3.19Å; S61-G64 PolarHBondContact O-N 3.21Å; S61-G64 VanDerWaalsContact O-N 3.11Å; S61-V65 WeakPolarHBondContact O-CG2 3.24Å; S61-V65 PolarHBondContact O-N 3.49Å; S61-S237 WeakPolarHBondContact CB-O 3.44Å; S61-S237 PolarHBondContact OG-O 2.89Å; S61-S241 WeakPolarHBondContact CB-OG 3.48Å; S61-S241 PolarHBondContact OG-OG 2.95Å
62	P	95.3	Very high	90.9	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-55.3	-39.7	178.7	-29.3	36.7	0	0	0	113.8	I58 L66 W79 N281 Y284	I58-P62 WeakPolarHBondContact O-CD 3.41Å; I58-P62 WeakPolarHBondContact O-CG 3.21Å; P62-L66 VanDerWaalsContact O-CB 3.27Å; P62-L66 WeakPolarHBondContact O-CB 3.42Å; P62-L66 PolarHBondContact O-N 2.82Å; P62-W79 HydrophobicContact CG-CZ2 4.22Å; P62-N281 WeakPolarHBondContact CB-OD1 3.29Å; P62-Y284 HydrophobicContact CB-CD2 4.25Å; P62-Y284 HydrophobicContact CB-CE2 4.49Å; P62-Y284 HydrophobicContact CG-CD2 4.16Å; P62-Y284 HydrophobicContact CG-CE2 3.97Å
63	K	94.9	Very high	91.6	Very high	28 Å²	28	14.3 Å²	14.3	12%	0.122	8%	0.083	C	C	.	.	H	α-helix	trans	-64.9	-49.4	174.7	172.1	168.3	170.1	171.4	0	110.7	V60 S61 V65 L66 I67 L294 S296 D297 V299 F382	V60-K63 PolarHBondContact O-N 3.44Å; S61-K63 VanDerWaalsContact C-N 3.27Å; S61-K63 PolarHBondContact O-N 3.19Å; K63-V65 PolarHBondContact O-N 3.04Å; K63-L66 PolarHBondContact O-N 3.14Å; K63-I67 HydrophobicContact CG-CD1 3.91Å; K63-I67 HydrophobicContact CG-CG1 4.46Å; K63-I67 VanDerWaalsContact O-CG1 3.27Å; K63-I67 WeakPolarHBondContact O-CG1 3.4Å; K63-I67 PolarHBondContact O-N 3.08Å; K63-L294 WeakPolarHBondContact CE-O 3.48Å; K63-L294 PolarHBondContact NZ-O 3.03Å; K63-L294 VanDerWaalsContact NZ-O 3.1Å; K63-S296 WeakPolarHBondContact CD-O 3.31Å; K63-S296 PolarHBondContact NZ-O 3.4Å; K63-D297 IonicContact NZ-OD1 2.69Å; K63-D297 PolarHBondContact NZ-OD1 3.45Å; K63-V299 HydrophobicContact CB-CG2 4.3Å; K63-F382 HydrophobicContact CB-CZ 4.1Å; K63-F382 HydrophobicContact CD-CE2 4.36Å; K63-F382 HydrophobicContact CD-CZ 4.28Å; K63-F382 HydrophobicContact CG-CE2 4.2Å; K63-F382 HydrophobicContact CG-CZ 3.85Å
64	G	93.7	Very high	92.1	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-59.6	-46.8	178.7	0	0	0	0	0	113.5	S61 L66 I67 Y68	S61-G64 PolarHBondContact O-N 3.21Å; S61-G64 VanDerWaalsContact O-N 3.11Å; G64-L66 VanDerWaalsContact C-N 3.31Å; G64-L66 PolarHBondContact O-N 2.86Å; G64-I67 PolarHBondContact O-N 3.37Å; G64-Y68 WeakPolarHBondContact O-CD2 3.15Å; G64-Y68 PolarHBondContact O-N 2.7Å
65	V	96.6	Very high	92.6	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-62.4	-41.1	176.9	-179.4	0	0	0	0	110.5	S61 K63 S69 S75 I78 W79 A234 A238	S61-V65 WeakPolarHBondContact O-CG2 3.24Å; S61-V65 PolarHBondContact O-N 3.49Å; K63-V65 PolarHBondContact O-N 3.04Å; V65-S69 WeakPolarHBondContact O-CB 3.48Å; V65-S69 PolarHBondContact O-N 2.69Å; V65-S69 PolarHBondContact O-OG 2.98Å; V65-S75 VanDerWaalsContact CG1-OG 3.25Å; V65-S75 WeakPolarHBondContact CG1-OG 3.29Å; V65-I78 HydrophobicContact CG1-CB 4.21Å; V65-I78 HydrophobicContact CG1-CG2 3.97Å; V65-W79 HydrophobicContact CG2-CZ2 4.24Å; V65-A234 HydrophobicContact CG1-CB 4.48Å; V65-A238 HydrophobicContact CG2-CB 3.93Å
66	L	95.6	Very high	93.4	Very high	7 Å²	7	16.6 Å²	16.6	4%	0.037	9%	0.093	C	C	.	.	H	α-helix	trans	-69.8	-36.8	-179.5	-170.1	62.4	0	0	0	112.9	P62 K63 G64 Y68 S69 A70 Y72 Y285 I293 L294	P62-L66 VanDerWaalsContact O-CB 3.27Å; P62-L66 WeakPolarHBondContact O-CB 3.42Å; P62-L66 PolarHBondContact O-N 2.82Å; K63-L66 PolarHBondContact O-N 3.14Å; G64-L66 VanDerWaalsContact C-N 3.31Å; G64-L66 PolarHBondContact O-N 2.86Å; L66-Y68 VanDerWaalsContact C-N 3.33Å; L66-Y68 PolarHBondContact O-N 2.69Å; L66-S69 WeakPolarHBondContact CA-OG 3.39Å; L66-A70 WeakPolarHBondContact O-CA 3.31Å; L66-A70 PolarHBondContact O-N 3.39Å; L66-Y72 HydrophobicContact CD1-CD1 3.69Å; L66-Y72 HydrophobicContact CD1-CE1 4.06Å; L66-Y72 HydrophobicContact CD2-CD1 4.4Å; L66-Y72 HydrophobicContact CD2-CE1 4.05Å; L66-Y285 HydrophobicContact CD2-CE1 4.37Å; L66-I293 HydrophobicContact CD2-CB 3.92Å; L66-I293 HydrophobicContact CD2-CD1 4.13Å; L66-I293 HydrophobicContact CD2-CG2 3.78Å; L66-L294 HydrophobicContact CB-CD2 4.38Å; L66-L294 HydrophobicContact CD2-CD2 4.42Å; L66-L294 HydrophobicContact CD2-CG 4.37Å; L66-L294 HydrophobicContact CG-CD2 4.34Å
67	I	94.5	Very high	94.2	Very high	73 Å²	73	19.1 Å²	19.1	37%	0.374	11%	0.108	S	C	.	.	H	α-helix	trans	-53	-52.2	175.1	-73.7	165.1	0	0	0	110.3	K63 G64 L294 F382	K63-I67 HydrophobicContact CG-CD1 3.91Å; K63-I67 HydrophobicContact CG-CG1 4.46Å; K63-I67 VanDerWaalsContact O-CG1 3.27Å; K63-I67 WeakPolarHBondContact O-CG1 3.4Å; K63-I67 PolarHBondContact O-N 3.08Å; G64-I67 PolarHBondContact O-N 3.37Å; I67-L294 HydrophobicContact CB-CD2 4.31Å; I67-L294 HydrophobicContact CD1-CD2 4.46Å; I67-L294 HydrophobicContact CG1-CD2 3.38Å; I67-F382 HydrophobicContact CD1-CD2 4.48Å; I67-F382 HydrophobicContact CD1-CE2 4.08Å; I67-F382 HydrophobicContact CD1-CZ 4.44Å
68	Y	94.4	Very high	94.7	Very high	45 Å²	45	19 Å²	19	18%	0.176	11%	0.106	C	C	.	.	H	α-helix	trans	-86.4	-30.6	-173.5	-62.6	-66.8	0	0	0	113.5	G64 L66 S225 D230 L233	G64-Y68 WeakPolarHBondContact O-CD2 3.15Å; G64-Y68 PolarHBondContact O-N 2.7Å; L66-Y68 VanDerWaalsContact C-N 3.33Å; L66-Y68 PolarHBondContact O-N 2.69Å; Y68-S225 VanDerWaalsContact O-CB 3.25Å; Y68-S225 WeakPolarHBondContact O-CB 3.18Å; Y68-D230 VanDerWaalsContact CB-O 3.31Å; Y68-D230 WeakPolarHBondContact CB-O 3.44Å; Y68-D230 WeakPolarHBondContact O-CB 3.38Å; Y68-L233 HydrophobicContact CD1-CB 3.91Å; Y68-L233 HydrophobicContact CD1-CD1 4.07Å; Y68-L233 HydrophobicContact CD2-CB 3.77Å; Y68-L233 HydrophobicContact CE1-CB 3.91Å; Y68-L233 HydrophobicContact CE1-CD1 3.54Å; Y68-L233 HydrophobicContact CE1-CG 4.38Å; Y68-L233 HydrophobicContact CE2-CB 3.79Å; Y68-L233 HydrophobicContact CG-CB 3.86Å
69	S	94.7	Very high	94.9	Very high	1 Å²	1	19 Å²	19	1%	0.007	11%	0.106	C	C	.	.	H	α-helix	trans	-76.1	-25.6	176.7	62.5	0	0	0	0	113.2	V65 L66 S71 S75 S224 S225	V65-S69 WeakPolarHBondContact O-CB 3.48Å; V65-S69 PolarHBondContact O-N 2.69Å; V65-S69 PolarHBondContact O-OG 2.98Å; L66-S69 WeakPolarHBondContact CA-OG 3.39Å; S69-S71 PolarHBondContact O-N 2.96Å; S69-S71 PolarHBondContact OG-O 2.93Å; S69-S75 WeakPolarHBondContact OG-CB 3.41Å; S69-S224 WeakPolarHBondContact O-CA 3.09Å; S69-S225 PolarHBondContact O-N 3.02Å
70	A	93.5	Very high	95.3	Very high	57 Å²	57	20.9 Å²	20.9	47%	0.471	12%	0.122	S	C	.	.			trans	56.5	4.6	-178.2	0	0	0	0	0	115.6	L66 G223	L66-A70 WeakPolarHBondContact O-CA 3.31Å; L66-A70 PolarHBondContact O-N 3.39Å; A70-G223 VanDerWaalsContact CB-O 3.24Å; A70-G223 WeakPolarHBondContact CB-O 3.11Å
71	S	94.2	Very high	95.5	Very high	6 Å²	6	24.1 Å²	24.1	4%	0.042	14%	0.138	C	C	.	.	S	Bend	trans	-150.1	146.9	178.8	85.2	0	0	0	0	111.4	S69 G73 L74 S75 S220 S224	S69-S71 PolarHBondContact O-N 2.96Å; S69-S71 PolarHBondContact OG-O 2.93Å; S71-G73 VanDerWaalsContact C-N 3.33Å; S71-G73 PolarHBondContact O-N 3.28Å; S71-L74 WeakPolarHBondContact OG-CB 3.43Å; S71-L74 PolarHBondContact OG-N 2.95Å; S71-L74 VanDerWaalsContact OG-N 3.12Å; S71-S75 WeakPolarHBondContact O-CB 3.32Å; S71-S75 PolarHBondContact O-N 3.25Å; S71-S220 VanDerWaalsContact CB-O 3.29Å; S71-S220 WeakPolarHBondContact CB-O 3.33Å; S71-S220 PolarHBondContact OG-O 3.09Å; S71-S224 WeakPolarHBondContact CB-OG 3.27Å; S71-S224 PolarHBondContact OG-OG 3.33Å
72	Y	94.3	Very high	95.5	Very high	33 Å²	33	24.1 Å²	24.1	13%	0.129	14%	0.138	C	C	.	.	H	α-helix	trans	-66.3	-37.7	179.7	-52.6	-46.2	0	0	0	112.2	L66 S75 L76 N216 S220 Y285 G290	L66-Y72 HydrophobicContact CD1-CD1 3.69Å; L66-Y72 HydrophobicContact CD1-CE1 4.06Å; L66-Y72 HydrophobicContact CD2-CD1 4.4Å; L66-Y72 HydrophobicContact CD2-CE1 4.05Å; Y72-S75 WeakPolarHBondContact O-CB 3.34Å; Y72-S75 PolarHBondContact O-N 3.04Å; Y72-L76 WeakPolarHBondContact O-CG 3.3Å; Y72-L76 PolarHBondContact O-N 2.83Å; Y72-N216 HydrophobicContact CD2-CB 4.22Å; Y72-N216 VanDerWaalsContact CD2-O 3.24Å; Y72-N216 WeakPolarHBondContact CD2-O 3.14Å; Y72-N216 HydrophobicContact CE2-CB 3.68Å; Y72-S220 PolarHBondContact N-O 3.25Å; Y72-Y285 AromaticContact CD1-CD1 3.67Å; Y72-Y285 HydrophobicContact CD1-CD1 3.67Å; Y72-Y285 HydrophobicContact CD1-CD2 4.15Å; Y72-Y285 AromaticContact CD1-CE1 3.92Å; Y72-Y285 HydrophobicContact CD1-CE1 3.92Å; Y72-Y285 HydrophobicContact CD1-CE2 4.35Å; Y72-Y285 AromaticContact CD1-CG 3.82Å; Y72-Y285 HydrophobicContact CD1-CG 3.82Å; Y72-Y285 AromaticContact CE1-CD1 4Å; Y72-Y285 HydrophobicContact CE1-CD1 4Å; Y72-Y285 HydrophobicContact CE1-CE1 4.38Å; Y72-Y285 HydrophobicContact CE1-CG 4.43Å; Y72-Y285 HydrophobicContact CG-CD1 4.4Å; Y72-Y285 HydrophobicContact CG-CD2 4.2Å; Y72-Y285 HydrophobicContact CG-CG 4.08Å; Y72-G290 VanDerWaalsContact OH-CA 3.31Å; Y72-G290 WeakPolarHBondContact OH-CA 3.28Å; Y72-G290 PolarHBondContact OH-N 3.16Å
73	G	94.6	Very high	95.5	Very high	5 Å²	5	24.2 Å²	24.2	5%	0.052	14%	0.138	C	C	.	.	H	α-helix	trans	-64.6	-47.8	-179.7	0	0	0	0	0	111.7	S71 L76 V77 S220	S71-G73 VanDerWaalsContact C-N 3.33Å; S71-G73 PolarHBondContact O-N 3.28Å; G73-L76 PolarHBondContact O-N 3.43Å; G73-V77 WeakPolarHBondContact O-CG2 3.5Å; G73-V77 PolarHBondContact O-N 3.45Å; G73-V77 VanDerWaalsContact O-N 3.16Å; G73-S220 WeakPolarHBondContact CA-O 3.36Å; G73-S220 PolarHBondContact N-O 3.38Å
74	L	95.9	Very high	95.5	Very high	28 Å²	28	28.3 Å²	28.3	15%	0.147	16%	0.161	C	C	.	.	H	α-helix	trans	-67.4	-38.8	176.5	-177.6	59.4	0	0	0	111.3	S71 L76 V77 I78 S225	S71-L74 WeakPolarHBondContact OG-CB 3.43Å; S71-L74 PolarHBondContact OG-N 2.95Å; S71-L74 VanDerWaalsContact OG-N 3.12Å; L74-L76 PolarHBondContact O-N 3.14Å; L74-V77 WeakPolarHBondContact O-CB 3.39Å; L74-V77 PolarHBondContact O-N 3.47Å; L74-I78 HydrophobicContact CD1-CD1 4.18Å; L74-I78 HydrophobicContact CD1-CG1 4.34Å; L74-I78 HydrophobicContact CD2-CD1 4.4Å; L74-I78 HydrophobicContact CG-CD1 3.77Å; L74-I78 HydrophobicContact CG-CG1 4.41Å; L74-I78 WeakPolarHBondContact O-CD1 3.28Å; L74-I78 WeakPolarHBondContact O-CG1 3.27Å; L74-I78 PolarHBondContact O-N 3.34Å; L74-S225 WeakPolarHBondContact CD2-O 3.3Å
75	S	96.8	Very high	95.5	Very high	0 Å²	0	29.2 Å²	29.2	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-54.1	-50.9	173.5	176.5	0	0	0	0	112.1	V65 S69 S71 Y72 V77 I78 W79 Y285	V65-S75 VanDerWaalsContact CG1-OG 3.25Å; V65-S75 WeakPolarHBondContact CG1-OG 3.29Å; S69-S75 WeakPolarHBondContact OG-CB 3.41Å; S71-S75 WeakPolarHBondContact O-CB 3.32Å; S71-S75 PolarHBondContact O-N 3.25Å; Y72-S75 WeakPolarHBondContact O-CB 3.34Å; Y72-S75 PolarHBondContact O-N 3.04Å; S75-V77 VanDerWaalsContact C-N 3.3Å; S75-V77 PolarHBondContact O-N 3.2Å; S75-I78 WeakPolarHBondContact O-CB 3.24Å; S75-I78 PolarHBondContact O-N 2.94Å; S75-I78 VanDerWaalsContact O-N 3.1Å; S75-W79 PolarHBondContact O-N 3.41Å; S75-Y285 WeakPolarHBondContact CB-OH 3.23Å; S75-Y285 PolarHBondContact OG-OH 2.62Å
76	L	96.8	Very high	95.3	Very high	34 Å²	34	29.2 Å²	29.2	18%	0.178	17%	0.165	C	C	.	.	H	α-helix	trans	-62.5	-36.9	179.1	-68.6	175.1	0	0	0	112.5	Y72 G73 L74 W79 A80 F217 N281 V282 Y285	Y72-L76 WeakPolarHBondContact O-CG 3.3Å; Y72-L76 PolarHBondContact O-N 2.83Å; G73-L76 PolarHBondContact O-N 3.43Å; L74-L76 PolarHBondContact O-N 3.14Å; L76-W79 PolarHBondContact O-N 3.22Å; L76-A80 PolarHBondContact O-N 3.28Å; L76-F217 HydrophobicContact CD1-CE1 4.48Å; L76-N281 HydrophobicContact CD2-CB 3.75Å; L76-V282 HydrophobicContact CD1-CG2 3.94Å; L76-V282 HydrophobicContact CD2-CG2 3.86Å; L76-Y285 HydrophobicContact CD1-CD2 4.46Å; L76-Y285 HydrophobicContact CD2-CD2 4.23Å; L76-Y285 HydrophobicContact CD2-CE2 3.97Å; L76-Y285 HydrophobicContact CG-CD2 4.25Å; L76-Y285 HydrophobicContact CG-CE2 4.03Å
77	V	96.9	Very high	95.2	Very high	60 Å²	60	30.7 Å²	30.7	36%	0.364	17%	0.174	S	C	.	.	H	α-helix	trans	-63.3	-42.7	173.5	170.3	0	0	0	0	110.8	G73 L74 S75 W79 A80 I81 F221	G73-V77 WeakPolarHBondContact O-CG2 3.5Å; G73-V77 PolarHBondContact O-N 3.45Å; G73-V77 VanDerWaalsContact O-N 3.16Å; L74-V77 WeakPolarHBondContact O-CB 3.39Å; L74-V77 PolarHBondContact O-N 3.47Å; S75-V77 VanDerWaalsContact C-N 3.3Å; S75-V77 PolarHBondContact O-N 3.2Å; V77-W79 PolarHBondContact O-N 2.83Å; V77-A80 PolarHBondContact O-N 2.8Å; V77-I81 HydrophobicContact CG1-CD1 3.63Å; V77-I81 HydrophobicContact CG1-CG1 4.24Å; V77-I81 WeakPolarHBondContact O-CB 3.36Å; V77-I81 VanDerWaalsContact O-CG1 3.3Å; V77-I81 WeakPolarHBondContact O-CG1 3.41Å; V77-I81 PolarHBondContact O-N 2.94Å; V77-F221 HydrophobicContact CG2-CE1 4.27Å; V77-F221 HydrophobicContact CG2-CZ 4.5Å
78	I	97.2	Very high	95.2	Very high	3 Å²	3	28.1 Å²	28.1	2%	0.015	16%	0.162	C	C	.	.	H	α-helix	trans	-63.5	-41.6	177.6	-71.9	159.2	0	0	0	111.2	V65 L74 S75 A80 I81 G82 A234 L235 A238	V65-I78 HydrophobicContact CG1-CB 4.21Å; V65-I78 HydrophobicContact CG1-CG2 3.97Å; L74-I78 HydrophobicContact CD1-CD1 4.18Å; L74-I78 HydrophobicContact CD1-CG1 4.34Å; L74-I78 HydrophobicContact CD2-CD1 4.4Å; L74-I78 HydrophobicContact CG-CD1 3.77Å; L74-I78 HydrophobicContact CG-CG1 4.41Å; L74-I78 WeakPolarHBondContact O-CD1 3.28Å; L74-I78 WeakPolarHBondContact O-CG1 3.27Å; L74-I78 PolarHBondContact O-N 3.34Å; S75-I78 WeakPolarHBondContact O-CB 3.24Å; S75-I78 PolarHBondContact O-N 2.94Å; S75-I78 VanDerWaalsContact O-N 3.1Å; I78-A80 PolarHBondContact O-N 3.49Å; I78-I81 PolarHBondContact O-N 2.88Å; I78-G82 PolarHBondContact O-N 3.06Å; I78-A234 HydrophobicContact CD1-CB 3.65Å; I78-A234 HydrophobicContact CG2-CB 4.14Å; I78-L235 HydrophobicContact CG2-CD2 3.95Å; I78-L235 HydrophobicContact CG2-CG 4.12Å; I78-A238 HydrophobicContact CG2-CB 4.08Å
79	W	97.4	Very high	95.1	Very high	0 Å²	0	26 Å²	26	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-59.4	-45.5	172.4	-80.9	102.5	0	0	0	112	I58 P62 V65 S75 L76 V77 G82 G83 A238 S241 Y242 Y277 I278 N281	I58-W79 HydrophobicContact CD1-CH2 3.51Å; I58-W79 HydrophobicContact CD1-CZ2 4.07Å; I58-W79 HydrophobicContact CD1-CZ3 3.93Å; P62-W79 HydrophobicContact CG-CZ2 4.22Å; V65-W79 HydrophobicContact CG2-CZ2 4.24Å; S75-W79 PolarHBondContact O-N 3.41Å; L76-W79 PolarHBondContact O-N 3.22Å; V77-W79 PolarHBondContact O-N 2.83Å; W79-G82 PolarHBondContact O-N 2.77Å; W79-G83 PolarHBondContact O-N 3.48Å; W79-A238 HydrophobicContact CD2-CB 4.33Å; W79-A238 HydrophobicContact CE3-CB 4.34Å; W79-S241 WeakPolarHBondContact CH2-OG 3.21Å; W79-Y242 AromaticContact CE3-CE2 3.64Å; W79-Y242 HydrophobicContact CE3-CE2 3.64Å; W79-Y242 HydrophobicContact CZ3-CE2 4.05Å; W79-Y242 WeakPolarHBondContact O-CE2 3.14Å; W79-Y242 PolarHBondContact O-OH 3.14Å; W79-Y277 AromaticContact CE3-CD2 3.96Å; W79-Y277 HydrophobicContact CE3-CD2 3.96Å; W79-Y277 HydrophobicContact CE3-CG 4.31Å; W79-Y277 HydrophobicContact CH2-CD2 4.49Å; W79-Y277 AromaticContact CZ3-CD2 3.45Å; W79-Y277 HydrophobicContact CZ3-CD2 3.45Å; W79-Y277 VanDerWaalsContact CZ3-CD2 3.45Å; W79-Y277 HydrophobicContact CZ3-CE2 4.13Å; W79-Y277 AromaticContact CZ3-CG 3.92Å; W79-Y277 HydrophobicContact CZ3-CG 3.92Å; W79-I278 HydrophobicContact CB-CG1 4.33Å; W79-N281 WeakPolarHBondContact CZ2-ND2 3.26Å; W79-N281 PolarHBondContact NE1-ND2 3.02Å; W79-N281 PolarHBondContact NE1-OD1 3.19Å
80	A	96.9	Very high	95	Very high	41 Å²	41	26 Å²	26	34%	0.339	15%	0.153	S	C	.	.	H	α-helix	trans	-64	-44	177.9	0	0	0	0	0	112.6	L76 V77 I78 G83 L84 I278	L76-A80 PolarHBondContact O-N 3.28Å; V77-A80 PolarHBondContact O-N 2.8Å; I78-A80 PolarHBondContact O-N 3.49Å; A80-G83 PolarHBondContact O-N 3.47Å; A80-L84 PolarHBondContact O-N 3.39Å; A80-I278 HydrophobicContact CB-CD1 3.97Å
81	I	96.1	Very high	94.9	Very high	86 Å²	86	24.9 Å²	24.9	44%	0.441	14%	0.14	S	C	.	.	H	α-helix	trans	-63.6	-42.6	175.8	-69.2	171.5	0	0	0	110.4	V77 I78 G83 L84 F85 L235	V77-I81 HydrophobicContact CG1-CD1 3.63Å; V77-I81 HydrophobicContact CG1-CG1 4.24Å; V77-I81 WeakPolarHBondContact O-CB 3.36Å; V77-I81 VanDerWaalsContact O-CG1 3.3Å; V77-I81 WeakPolarHBondContact O-CG1 3.41Å; V77-I81 PolarHBondContact O-N 2.94Å; I78-I81 PolarHBondContact O-N 2.88Å; I81-G83 PolarHBondContact O-N 2.79Å; I81-L84 PolarHBondContact O-N 2.82Å; I81-F85 WeakPolarHBondContact O-CB 3.41Å; I81-F85 PolarHBondContact O-N 3.41Å; I81-L235 HydrophobicContact CG2-CD2 4.06Å
82	G	95.3	Very high	94.9	Very high	0 Å²	0	24.6 Å²	24.6	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-61	-42.2	176.8	0	0	0	0	0	112.6	I78 W79 S86 L239	I78-G82 PolarHBondContact O-N 3.06Å; W79-G82 PolarHBondContact O-N 2.77Å; G82-S86 WeakPolarHBondContact O-CB 3.39Å; G82-S86 PolarHBondContact O-N 3.43Å; G82-S86 PolarHBondContact O-OG 3.2Å; G82-L239 WeakPolarHBondContact O-CD2 3.24Å
83	G	94.6	Very high	94.8	Very high	1 Å²	1	23 Å²	23	1%	0.01	13%	0.131	C	C	.	.	H	α-helix	trans	-63.4	-46.6	173.7	0	0	0	0	0	112.4	W79 A80 I81 S86 V87	W79-G83 PolarHBondContact O-N 3.48Å; A80-G83 PolarHBondContact O-N 3.47Å; I81-G83 PolarHBondContact O-N 2.79Å; G83-S86 PolarHBondContact O-N 2.96Å; G83-V87 WeakPolarHBondContact O-CG2 3.45Å; G83-V87 PolarHBondContact O-N 3.36Å
84	L	94.6	Very high	94.6	Very high	115 Å²	115	22.8 Å²	22.8	60%	0.602	13%	0.129	S	C	*	.	H	α-helix	trans	-62	-46.2	177.6	-179.9	62.4	0	0	0	112	A80 I81 S86 V87 V88	A80-L84 PolarHBondContact O-N 3.39Å; I81-L84 PolarHBondContact O-N 2.82Å; L84-S86 VanDerWaalsContact C-N 3.29Å; L84-S86 PolarHBondContact O-N 3.06Å; L84-V87 WeakPolarHBondContact O-CB 3.42Å; L84-V87 PolarHBondContact O-N 3.29Å; L84-V88 WeakPolarHBondContact O-CG2 3.43Å; L84-V88 PolarHBondContact O-N 2.96Å; L84-V88 VanDerWaalsContact O-N 3.11Å
85	F	94.4	Very high	94.4	Very high	18 Å²	18	21.5 Å²	21.5	8%	0.079	12%	0.122	C	C	.	.	H	α-helix	trans	-59.2	-41.8	175.9	172.9	-110.6	0	0	0	111.6	I81 V87 V88 G89 L239 W393 F427 C430 L434	I81-F85 WeakPolarHBondContact O-CB 3.41Å; I81-F85 PolarHBondContact O-N 3.41Å; F85-V87 PolarHBondContact O-N 3.21Å; F85-V88 PolarHBondContact O-N 3.24Å; F85-G89 PolarHBondContact O-N 3.49Å; F85-L239 HydrophobicContact CD1-CD1 3.85Å; F85-L239 HydrophobicContact CD1-CD2 3.62Å; F85-L239 HydrophobicContact CD1-CG 4.41Å; F85-L239 HydrophobicContact CE1-CD1 3.88Å; F85-L239 HydrophobicContact CE1-CD2 4.26Å; F85-W393 HydrophobicContact CD1-CH2 4.39Å; F85-W393 HydrophobicContact CD1-CZ3 4.35Å; F85-W393 HydrophobicContact CE1-CD2 4.2Å; F85-W393 AromaticContact CE1-CE3 3.64Å; F85-W393 HydrophobicContact CE1-CE3 3.64Å; F85-W393 AromaticContact CE1-CH2 3.77Å; F85-W393 HydrophobicContact CE1-CH2 3.77Å; F85-W393 HydrophobicContact CE1-CZ2 4.33Å; F85-W393 AromaticContact CE1-CZ3 3.38Å; F85-W393 HydrophobicContact CE1-CZ3 3.38Å; F85-W393 AromaticContact CZ-CE3 3.94Å; F85-W393 HydrophobicContact CZ-CE3 3.94Å; F85-W393 AromaticContact CZ-CZ3 3.91Å; F85-W393 HydrophobicContact CZ-CZ3 3.91Å; F85-F427 HydrophobicContact CD2-CD2 4.02Å; F85-F427 HydrophobicContact CD2-CE2 4.29Å; F85-F427 AromaticContact CE1-CE2 3.99Å; F85-F427 HydrophobicContact CE1-CE2 3.99Å; F85-F427 AromaticContact CE2-CD2 3.34Å; F85-F427 HydrophobicContact CE2-CD2 3.34Å; F85-F427 AromaticContact CE2-CE2 3.49Å; F85-F427 HydrophobicContact CE2-CE2 3.49Å; F85-F427 VanDerWaalsContact CE2-CE2 3.49Å; F85-F427 HydrophobicContact CE2-CG 4.14Å; F85-F427 HydrophobicContact CE2-CZ 4.4Å; F85-F427 AromaticContact CZ-CD2 3.73Å; F85-F427 HydrophobicContact CZ-CD2 3.73Å; F85-F427 AromaticContact CZ-CE2 3.34Å; F85-F427 HydrophobicContact CZ-CE2 3.34Å; F85-F427 AromaticContact CZ-CZ 3.96Å; F85-F427 HydrophobicContact CZ-CZ 3.96Å; F85-C430 HydrophobicContact CD2-CB 3.55Å; F85-C430 HydrophobicContact CE2-CB 3.25Å; F85-C430 HydrophobicContact CZ-CB 4.16Å; F85-L434 HydrophobicContact CD1-CD1 4.42Å; F85-L434 HydrophobicContact CE1-CD1 3.62Å; F85-L434 HydrophobicContact CZ-CD1 3.81Å
86	S	93.4	Very high	94.2	Very high	0 Å²	0	21.7 Å²	21.7	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-65.6	-36.5	177.1	-57.4	0	0	0	0	112.4	G82 G83 L84 G89 A90 Y242	G82-S86 WeakPolarHBondContact O-CB 3.39Å; G82-S86 PolarHBondContact O-N 3.43Å; G82-S86 PolarHBondContact O-OG 3.2Å; G83-S86 PolarHBondContact O-N 2.96Å; L84-S86 VanDerWaalsContact C-N 3.29Å; L84-S86 PolarHBondContact O-N 3.06Å; S86-G89 PolarHBondContact O-N 3.32Å; S86-A90 VanDerWaalsContact O-CB 3.27Å; S86-A90 WeakPolarHBondContact O-CB 3.17Å; S86-A90 PolarHBondContact O-N 3.43Å; S86-Y242 WeakPolarHBondContact OG-CB 3.44Å
87	V	92.8	Very high	93.7	Very high	39 Å²	39	20 Å²	20	24%	0.236	12%	0.115	C	C	.	.	H	α-helix	trans	-60.2	-47.3	173.1	171.1	0	0	0	0	110.4	G83 L84 F85 G89 A90 L91 M270	G83-V87 WeakPolarHBondContact O-CG2 3.45Å; G83-V87 PolarHBondContact O-N 3.36Å; L84-V87 WeakPolarHBondContact O-CB 3.42Å; L84-V87 PolarHBondContact O-N 3.29Å; F85-V87 PolarHBondContact O-N 3.21Å; V87-G89 VanDerWaalsContact C-N 3.33Å; V87-G89 PolarHBondContact O-N 3.34Å; V87-A90 PolarHBondContact O-N 3.42Å; V87-L91 HydrophobicContact CG1-CD1 4.01Å; V87-L91 HydrophobicContact CG1-CG 4.45Å; V87-L91 WeakPolarHBondContact O-CB 3.44Å; V87-L91 VanDerWaalsContact O-CG 3.3Å; V87-L91 WeakPolarHBondContact O-CG 3.38Å; V87-L91 PolarHBondContact O-N 3.43Å; V87-M270 HydrophobicContact CG2-CB 3.56Å; V87-M270 HydrophobicContact CG2-CE 4.31Å; V87-M270 HydrophobicContact CG2-CG 4.27Å
88	V	93.6	Very high	93.4	Very high	19 Å²	19	17.6 Å²	17.6	12%	0.115	10%	0.1	C	C	.	.	H	α-helix	trans	-60.5	-45.2	178.9	176.9	0	0	0	0	110.5	L84 F85 L91 C92 Y423 F427	L84-V88 WeakPolarHBondContact O-CG2 3.43Å; L84-V88 PolarHBondContact O-N 2.96Å; L84-V88 VanDerWaalsContact O-N 3.11Å; F85-V88 PolarHBondContact O-N 3.24Å; V88-L91 PolarHBondContact O-N 3.31Å; V88-C92 PolarHBondContact O-N 2.87Å; V88-C92 VanDerWaalsContact O-N 3.13Å; V88-C92 PolarHBondContact O-SG 2.81Å; V88-Y423 HydrophobicContact CG1-CD1 4.2Å; V88-Y423 WeakPolarHBondContact CG1-O 3.02Å; V88-Y423 HydrophobicContact CG2-CD1 4.43Å; V88-F427 HydrophobicContact CG1-CB 4.04Å
89	G	93	Very high	93	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-61.1	-48.2	176.4	0	0	0	0	0	113.1	F85 S86 V87 L91 C92 Y93 W245	F85-G89 PolarHBondContact O-N 3.49Å; S86-G89 PolarHBondContact O-N 3.32Å; V87-G89 VanDerWaalsContact C-N 3.33Å; V87-G89 PolarHBondContact O-N 3.34Å; G89-L91 VanDerWaalsContact C-N 3.33Å; G89-L91 PolarHBondContact O-N 2.81Å; G89-C92 WeakPolarHBondContact O-CB 3.49Å; G89-C92 PolarHBondContact O-N 2.92Å; G89-C92 VanDerWaalsContact O-N 3.15Å; G89-Y93 PolarHBondContact O-N 2.93Å; G89-W245 VanDerWaalsContact C-CH2 3.5Å
90	A	92.3	Very high	92.5	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-62.2	-39.1	180	0	0	0	0	0	112.1	S86 V87 Y93 A94 W245 I266 M270	S86-A90 VanDerWaalsContact O-CB 3.27Å; S86-A90 WeakPolarHBondContact O-CB 3.17Å; S86-A90 PolarHBondContact O-N 3.43Å; V87-A90 PolarHBondContact O-N 3.42Å; A90-Y93 CarbonylContact O-C 3.6Å; A90-Y93 PolarHBondContact O-N 2.84Å; A90-A94 WeakPolarHBondContact O-CB 3.15Å; A90-A94 PolarHBondContact O-N 3.44Å; A90-W245 VanDerWaalsContact CA-CE3 3.44Å; A90-W245 HydrophobicContact CB-CB 4.28Å; A90-W245 HydrophobicContact CB-CD2 3.8Å; A90-W245 HydrophobicContact CB-CE3 3.59Å; A90-W245 HydrophobicContact CB-CG 4.11Å; A90-W245 HydrophobicContact CB-CZ3 4.2Å; A90-I266 HydrophobicContact CB-CD1 4.34Å; A90-I266 HydrophobicContact CB-CG1 4.43Å; A90-I266 HydrophobicContact CB-CG2 3.41Å; A90-I266 VanDerWaalsContact CB-CG2 3.41Å; A90-M270 HydrophobicContact CB-CG 4.34Å; A90-M270 HydrophobicContact CB-SD 4.37Å
91	L	91.9	Very high	91.7	Very high	35 Å²	35	20.2 Å²	20.2	18%	0.183	11%	0.112	C	C	.	.	H	α-helix	trans	-62.8	-44.8	173.4	-72	173.4	0	0	0	111.9	V87 V88 G89 Y93 A94 E95 L419 Y423	V87-L91 HydrophobicContact CG1-CD1 4.01Å; V87-L91 HydrophobicContact CG1-CG 4.45Å; V87-L91 WeakPolarHBondContact O-CB 3.44Å; V87-L91 VanDerWaalsContact O-CG 3.3Å; V87-L91 WeakPolarHBondContact O-CG 3.38Å; V87-L91 PolarHBondContact O-N 3.43Å; V88-L91 PolarHBondContact O-N 3.31Å; G89-L91 VanDerWaalsContact C-N 3.33Å; G89-L91 PolarHBondContact O-N 2.81Å; L91-Y93 VanDerWaalsContact C-N 3.29Å; L91-Y93 PolarHBondContact O-N 2.95Å; L91-A94 WeakPolarHBondContact O-CB 3.44Å; L91-A94 PolarHBondContact O-N 2.9Å; L91-A94 VanDerWaalsContact O-N 3.11Å; L91-E95 PolarHBondContact O-N 3.38Å; L91-L419 VanDerWaalsContact C-CD1 3.41Å; L91-L419 HydrophobicContact CB-CD1 3.77Å; L91-L419 WeakPolarHBondContact O-CD1 3.33Å; L91-Y423 HydrophobicContact CD1-CD1 4.42Å; L91-Y423 HydrophobicContact CD1-CE1 4.21Å
92	C	93.7	Very high	90.8	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-60.2	-41.7	176.1	-63.1	0	0	0	0	111.5	V88 G89 E95 L96 V400 Q403	V88-C92 PolarHBondContact O-N 2.87Å; V88-C92 VanDerWaalsContact O-N 3.13Å; V88-C92 PolarHBondContact O-SG 2.81Å; G89-C92 WeakPolarHBondContact O-CB 3.49Å; G89-C92 PolarHBondContact O-N 2.92Å; G89-C92 VanDerWaalsContact O-N 3.15Å; C92-E95 WeakPolarHBondContact O-CB 3.42Å; C92-E95 PolarHBondContact O-N 2.79Å; C92-L96 PolarHBondContact O-N 2.92Å; C92-V400 HydrophobicContact CB-CG1 4.06Å; C92-V400 HydrophobicContact CB-CG2 3.93Å; C92-Q403 PolarHBondContact O-OE1 3.34Å
93	Y	92.1	Very high	89.6	Confident	0 Å²	0	23.1 Å²	23.1	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-67.6	-32.3	174.2	-93.7	-113.3	0	0	0	113.4	G89 A90 L91 E95 L96 G97 S106 Y109 W245 D246 N249 M396 S399 V400	G89-Y93 PolarHBondContact O-N 2.93Å; A90-Y93 CarbonylContact O-C 3.6Å; A90-Y93 PolarHBondContact O-N 2.84Å; L91-Y93 VanDerWaalsContact C-N 3.29Å; L91-Y93 PolarHBondContact O-N 2.95Å; Y93-E95 VanDerWaalsContact C-N 3.26Å; Y93-E95 PolarHBondContact O-N 3.28Å; Y93-L96 PolarHBondContact O-N 3.47Å; Y93-G97 PolarHBondContact O-N 3.39Å; Y93-S106 WeakPolarHBondContact CE1-OG 3.5Å; Y93-S106 PolarHBondContact OH-OG 3.43Å; Y93-Y109 HydrophobicContact CD1-CD2 4.37Å; Y93-Y109 AromaticContact CD1-CE2 3.83Å; Y93-Y109 HydrophobicContact CD1-CE2 3.83Å; Y93-Y109 HydrophobicContact CE1-CD2 4.07Å; Y93-Y109 AromaticContact CE1-CE2 3.91Å; Y93-Y109 HydrophobicContact CE1-CE2 3.91Å; Y93-W245 AromaticContact CD1-CZ3 3.94Å; Y93-W245 HydrophobicContact CD1-CZ3 3.94Å; Y93-W245 AromaticContact CD2-CH2 3.61Å; Y93-W245 HydrophobicContact CD2-CH2 3.61Å; Y93-W245 AromaticContact CD2-CZ3 3.64Å; Y93-W245 HydrophobicContact CD2-CZ3 3.64Å; Y93-W245 AromaticContact CE2-CH2 3.98Å; Y93-W245 HydrophobicContact CE2-CH2 3.98Å; Y93-W245 HydrophobicContact CE2-CZ3 4.31Å; Y93-W245 AromaticContact CG-CH2 3.94Å; Y93-W245 HydrophobicContact CG-CH2 3.94Å; Y93-W245 AromaticContact CG-CZ3 3.44Å; Y93-W245 HydrophobicContact CG-CZ3 3.44Å; Y93-W245 VanDerWaalsContact CG-CZ3 3.44Å; Y93-D246 HydrophobicContact CD1-CB 4.17Å; Y93-D246 HydrophobicContact CE1-CB 4.32Å; Y93-N249 PolarHBondContact O-ND2 3.41Å; Y93-M396 HydrophobicContact CD1-CE 4.39Å; Y93-M396 HydrophobicContact CD2-CE 4.24Å; Y93-M396 HydrophobicContact CE1-CE 3.73Å; Y93-M396 HydrophobicContact CE1-SD 4.24Å; Y93-M396 HydrophobicContact CE2-CE 3.56Å; Y93-M396 HydrophobicContact CE2-SD 4.3Å; Y93-M396 WeakPolarHBondContact OH-CE 3.39Å; Y93-M396 PolarHBondContact OH-SD 3.44Å; Y93-S399 WeakPolarHBondContact OH-CB 3.42Å; Y93-S399 PolarHBondContact OH-OG 3.43Å; Y93-V400 HydrophobicContact CD2-CG2 4.03Å; Y93-V400 HydrophobicContact CE2-CG2 3.78Å
94	A	90.9	Very high	88.5	Confident	0 Å²	0	23.4 Å²	23.4	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-61.6	-38.3	173.3	0	0	0	0	0	111.1	A90 L91 T98 L262 P263 I266 L417	A90-A94 WeakPolarHBondContact O-CB 3.15Å; A90-A94 PolarHBondContact O-N 3.44Å; L91-A94 WeakPolarHBondContact O-CB 3.44Å; L91-A94 PolarHBondContact O-N 2.9Å; L91-A94 VanDerWaalsContact O-N 3.11Å; A94-T98 WeakPolarHBondContact O-CB 3.46Å; A94-T98 VanDerWaalsContact O-CG2 3.28Å; A94-T98 WeakPolarHBondContact O-CG2 3.39Å; A94-T98 PolarHBondContact O-N 3.48Å; A94-T98 PolarHBondContact O-OG1 3.42Å; A94-L262 HydrophobicContact CB-CG 4.48Å; A94-P263 HydrophobicContact CB-CB 4.47Å; A94-P263 HydrophobicContact CB-CG 4.3Å; A94-I266 HydrophobicContact CB-CD1 3.81Å; A94-L417 HydrophobicContact CB-CD2 3.74Å
95	E	91.9	Very high	87.9	Confident	1 Å²	1	17.9 Å²	17.9	1%	0.005	10%	0.1	C	C	.	.	H	α-helix	trans	-66.9	-45.7	173.3	170.4	170.3	154.1	0	0	111.6	L91 C92 Y93 G97 T98 T99 Q403 R407 L417 L419	L91-E95 PolarHBondContact O-N 3.38Å; C92-E95 WeakPolarHBondContact O-CB 3.42Å; C92-E95 PolarHBondContact O-N 2.79Å; Y93-E95 VanDerWaalsContact C-N 3.26Å; Y93-E95 PolarHBondContact O-N 3.28Å; E95-G97 PolarHBondContact O-N 3.41Å; E95-T98 WeakPolarHBondContact CA-OG1 3.34Å; E95-T98 PolarHBondContact O-N 2.97Å; E95-T98 PolarHBondContact O-OG1 3.34Å; E95-T99 VanDerWaalsContact O-CB 3.31Å; E95-T99 WeakPolarHBondContact O-CB 3.35Å; E95-T99 PolarHBondContact O-N 3.29Å; E95-T99 PolarHBondContact O-OG1 3.23Å; E95-Q403 PolarHBondContact OE1-NE2 3.48Å; E95-Q403 PolarHBondContact OE2-NE2 3.4Å; E95-R407 IonicContact OE1-CZ 3.48Å; E95-R407 VanDerWaalsContact OE1-CZ 3.24Å; E95-R407 IonicContact OE1-NE 3.83Å; E95-R407 PolarHBondContact OE1-NE 3.36Å; E95-R407 IonicContact OE1-NH2 2.86Å; E95-R407 PolarHBondContact OE1-NH2 3.17Å; E95-R407 IonicContact OE2-CZ 2.82Å; E95-R407 IonicContact OE2-NH2 3.14Å; E95-R407 PolarHBondContact OE2-NH2 3.36Å; E95-L417 HydrophobicContact CB-CD2 4.21Å; E95-L417 WeakPolarHBondContact CG-O 3.44Å; E95-L419 HydrophobicContact CB-CD1 4.49Å; E95-L419 WeakPolarHBondContact OE2-CB 3.47Å; E95-L419 PolarHBondContact OE2-N 3.47Å
96	L	91.6	Very high	87.6	Confident	3 Å²	3	17 Å²	17	2%	0.016	10%	0.096	C	C	.	.	H	α-helix	trans	-60.6	-44.3	176.6	-77.4	171.1	0	0	0	112	C92 Y93 T98 T99 I100 Y109 Q403	C92-L96 PolarHBondContact O-N 2.92Å; Y93-L96 PolarHBondContact O-N 3.47Å; L96-T98 PolarHBondContact O-N 2.96Å; L96-T99 PolarHBondContact O-N 3.1Å; L96-I100 HydrophobicContact CD2-CD1 4.36Å; L96-I100 PolarHBondContact O-N 3.49Å; L96-Y109 HydrophobicContact CB-CD1 4.37Å; L96-Y109 HydrophobicContact CB-CD2 3.88Å; L96-Y109 HydrophobicContact CB-CE1 4.32Å; L96-Y109 HydrophobicContact CB-CE2 3.8Å; L96-Y109 HydrophobicContact CB-CG 4.18Å; L96-Y109 HydrophobicContact CD1-CD2 3.89Å; L96-Y109 HydrophobicContact CD1-CE2 4.47Å; L96-Y109 HydrophobicContact CD1-CG 4.33Å; L96-Y109 HydrophobicContact CG-CD2 4.42Å; L96-Q403 HydrophobicContact CD1-CB 4.22Å; L96-Q403 HydrophobicContact CD2-CB 3.7Å; L96-Q403 HydrophobicContact CD2-CG 3.91Å; L96-Q403 HydrophobicContact CG-CB 3.99Å; L96-Q403 HydrophobicContact CG-CG 4.05Å
97	G	87.9	Confident	87.4	Confident	0 Å²	0	17.2 Å²	17.2	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-68.9	-30.2	179.6	0	0	0	0	0	114.2	Y93 E95 Y109	Y93-G97 PolarHBondContact O-N 3.39Å; E95-G97 PolarHBondContact O-N 3.41Å; G97-Y109 WeakPolarHBondContact CA-OH 3.3Å; G97-Y109 PolarHBondContact N-OH 3.18Å
98	T	89.2	Confident	87.1	Confident	8 Å²	8	15.7 Å²	15.7	5%	0.049	9%	0.088	C	C	.	.	H	α-helix	trans	-79.4	-22.6	172.7	52.2	0	0	0	0	113	A94 E95 L96 L262 L417	A94-T98 WeakPolarHBondContact O-CB 3.46Å; A94-T98 VanDerWaalsContact O-CG2 3.28Å; A94-T98 WeakPolarHBondContact O-CG2 3.39Å; A94-T98 PolarHBondContact O-N 3.48Å; A94-T98 PolarHBondContact O-OG1 3.42Å; E95-T98 WeakPolarHBondContact CA-OG1 3.34Å; E95-T98 PolarHBondContact O-N 2.97Å; E95-T98 PolarHBondContact O-OG1 3.34Å; L96-T98 PolarHBondContact O-N 2.96Å; T98-L262 HydrophobicContact CG2-CD2 4.29Å; T98-L417 HydrophobicContact CG2-CB 4.48Å; T98-L417 WeakPolarHBondContact OG1-CB 3.21Å
99	T	89.6	Confident	87	Confident	19 Å²	19	14.8 Å²	14.8	12%	0.117	8%	0.083	C	C	.	.	H	α-helix	trans	-91.1	-36.3	179	-55.2	0	0	0	0	112.9	E95 L96 R413 R415	E95-T99 VanDerWaalsContact O-CB 3.31Å; E95-T99 WeakPolarHBondContact O-CB 3.35Å; E95-T99 PolarHBondContact O-N 3.29Å; E95-T99 PolarHBondContact O-OG1 3.23Å; L96-T99 PolarHBondContact O-N 3.1Å; T99-R413 HydrophobicContact CG2-CG 4.19Å; T99-R415 HydrophobicContact CG2-CG 4.04Å
100	I	87.3	Confident	87.1	Confident	3 Å²	3	14.8 Å²	14.8	2%	0.015	8%	0.083	C	C	.	.			trans	-121.5	89.8	-179.6	-53.2	170.4	0	0	0	106.7	L96 K102 Y109 E112 L406	L96-I100 HydrophobicContact CD2-CD1 4.36Å; L96-I100 PolarHBondContact O-N 3.49Å; I100-K102 HydrophobicContact CG2-CB 4.25Å; I100-K102 HydrophobicContact CG2-CG 4.43Å; I100-K102 PolarHBondContact O-N 3.16Å; I100-Y109 HydrophobicContact CB-CD1 3.85Å; I100-Y109 HydrophobicContact CB-CE1 3.91Å; I100-Y109 HydrophobicContact CD1-CD1 3.9Å; I100-Y109 HydrophobicContact CG1-CD1 4.45Å; I100-Y109 HydrophobicContact CG2-CD1 4Å; I100-Y109 HydrophobicContact CG2-CE1 4.22Å; I100-Y109 WeakPolarHBondContact O-CE1 3.43Å; I100-E112 HydrophobicContact CD1-CB 4.03Å; I100-E112 HydrophobicContact CD1-CG 4Å; I100-E112 HydrophobicContact CG1-CG 4.43Å; I100-L406 HydrophobicContact CD1-CD1 3.9Å
101	T	79.1	Confident	87	Confident	78 Å²	78	16.6 Å²	16.6	48%	0.479	9%	0.092	S	C	.	.			trans	-82	14.1	-176.7	61.9	0	0	0	0	113.3	E253	T101-E253 WeakPolarHBondContact O-CG 3.17Å
102	K	77.2	Confident	87	Confident	107 Å²	107	17.8 Å²	17.8	47%	0.465	10%	0.097	S	C	.	.			trans	-74.1	136.7	176.3	-67.5	178.5	179.8	169.3	0	109.5	I100 A108 E112	I100-K102 HydrophobicContact CG2-CB 4.25Å; I100-K102 HydrophobicContact CG2-CG 4.43Å; I100-K102 PolarHBondContact O-N 3.16Å; K102-A108 HydrophobicContact CB-CB 4.25Å; K102-E112 IonicContact NZ-OE2 3.74Å; K102-E112 PolarHBondContact NZ-OE2 3.25Å
103	S	69.9	Low	86.9	Confident	40 Å²	40	18.1 Å²	18.1	28%	0.28	10%	0.099	S	C	.	.	T	Hydrogen-bonded Turn	trans	-61.5	141.9	172.6	-61.6	0	0	0	0	112.2	E253	S103-E253 PolarHBondContact N-OE1 3.17Å; S103-E253 PolarHBondContact OG-OE1 3.34Å
104	G	71.9	Confident	87	Confident	6 Å²	6	21.8 Å²	21.8	6%	0.062	12%	0.115	C	C	.	.	T	Hydrogen-bonded Turn	trans	121.2	-1	179.7	0	0	0	0	0	115.7	S106 Y107	G104-S106 PolarHBondContact O-N 3.05Å; G104-Y107 WeakPolarHBondContact O-CB 3.49Å; G104-Y107 PolarHBondContact O-N 2.93Å; G104-Y107 VanDerWaalsContact O-N 3.11Å
105	A	82.8	Confident	87	Confident	0 Å²	0	23.2 Å²	23.2	0%	0	13%	0.13	C	C	.	.	T	Hydrogen-bonded Turn	trans	44.4	-120.5	175.9	0	0	0	0	0	112.9	Y107 A108 Y109 N249 F250	A105-Y107 PolarHBondContact O-N 3.47Å; A105-Y107 VanDerWaalsContact O-N 3.14Å; A105-A108 PolarHBondContact O-N 3.43Å; A105-Y109 HydrophobicContact CB-CE2 4.43Å; A105-Y109 WeakPolarHBondContact O-CD1 3.41Å; A105-Y109 VanDerWaalsContact O-CD2 3.31Å; A105-Y109 WeakPolarHBondContact O-CD2 3.33Å; A105-Y109 PolarHBondContact O-N 2.91Å; A105-N249 HydrophobicContact CB-CB 3.81Å; A105-F250 HydrophobicContact CB-CD1 3.71Å; A105-F250 HydrophobicContact CB-CD2 3.61Å; A105-F250 HydrophobicContact CB-CE1 3.63Å; A105-F250 HydrophobicContact CB-CE2 3.54Å; A105-F250 HydrophobicContact CB-CG 3.72Å; A105-F250 HydrophobicContact CB-CZ 3.56Å
106	S	86.8	Confident	86.9	Confident	0 Å²	0	24.1 Å²	24.1	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-52.3	-37.4	-177.4	-56.7	0	0	0	0	113.6	Y93 G104 I110	Y93-S106 WeakPolarHBondContact CE1-OG 3.5Å; Y93-S106 PolarHBondContact OH-OG 3.43Å; G104-S106 PolarHBondContact O-N 3.05Å; S106-I110 WeakPolarHBondContact O-CB 3.26Å; S106-I110 WeakPolarHBondContact O-CD1 3.29Å; S106-I110 VanDerWaalsContact O-CG1 3.26Å; S106-I110 WeakPolarHBondContact O-CG1 3.38Å; S106-I110 PolarHBondContact O-N 3.04Å
107	Y	89.2	Confident	87	Confident	4 Å²	4	27.2 Å²	27.2	2%	0.016	15%	0.153	C	C	.	.	H	α-helix	trans	-64.7	-48.4	176.4	168.4	-101.1	0	0	0	111.5	G104 A105 Y109 I110 L111 A119 L123 V340 E344 H346	G104-Y107 WeakPolarHBondContact O-CB 3.49Å; G104-Y107 PolarHBondContact O-N 2.93Å; G104-Y107 VanDerWaalsContact O-N 3.11Å; A105-Y107 PolarHBondContact O-N 3.47Å; A105-Y107 VanDerWaalsContact O-N 3.14Å; Y107-Y109 VanDerWaalsContact C-N 3.35Å; Y107-Y109 PolarHBondContact O-N 3.32Å; Y107-I110 PolarHBondContact O-N 2.84Å; Y107-L111 HydrophobicContact CE1-CD2 4.23Å; Y107-L111 VanDerWaalsContact O-CB 3.29Å; Y107-L111 WeakPolarHBondContact O-CB 3.48Å; Y107-L111 PolarHBondContact O-N 3.26Å; Y107-A119 HydrophobicContact CD2-CB 4.05Å; Y107-A119 WeakPolarHBondContact CD2-O 3.32Å; Y107-A119 HydrophobicContact CE2-CB 3.74Å; Y107-A119 WeakPolarHBondContact CE2-O 3.31Å; Y107-L123 HydrophobicContact CD2-CB 3.94Å; Y107-L123 HydrophobicContact CE2-CB 4.01Å; Y107-L123 HydrophobicContact CE2-CD2 4.09Å; Y107-V340 HydrophobicContact CE1-CG1 4.4Å; Y107-E344 HydrophobicContact CE1-CG 4.12Å; Y107-E344 VanDerWaalsContact OH-CB 3.3Å; Y107-E344 WeakPolarHBondContact OH-CB 3.44Å; Y107-H346 AromaticContact CE2-ND1 3.78Å; Y107-H346 AromaticContact CZ-ND1 3.72Å; Y107-H346 PolarHBondContact OH-CE1 3.4Å; Y107-H346 PolarHBondContact OH-ND1 3.43Å
108	A	87.8	Confident	87.3	Confident	6 Å²	6	29.6 Å²	29.6	5%	0.05	17%	0.165	C	C	.	.	H	α-helix	trans	-65.4	-37.6	179.2	0	0	0	0	0	112.1	K102 A105 L111 E112	K102-A108 HydrophobicContact CB-CB 4.25Å; A105-A108 PolarHBondContact O-N 3.43Å; A108-L111 PolarHBondContact O-N 3.47Å; A108-E112 WeakPolarHBondContact O-CB 3.41Å; A108-E112 PolarHBondContact O-N 3.03Å
109	Y	91.3	Very high	87.4	Confident	1 Å²	1	29.2 Å²	29.2	0%	0.004	16%	0.162	C	C	.	.	H	α-helix	trans	-67	-43.1	178.6	-55.5	-23.5	0	0	0	111.9	Y93 L96 G97 I100 A105 Y107 S113 N249	Y93-Y109 HydrophobicContact CD1-CD2 4.37Å; Y93-Y109 AromaticContact CD1-CE2 3.83Å; Y93-Y109 HydrophobicContact CD1-CE2 3.83Å; Y93-Y109 HydrophobicContact CE1-CD2 4.07Å; Y93-Y109 AromaticContact CE1-CE2 3.91Å; Y93-Y109 HydrophobicContact CE1-CE2 3.91Å; L96-Y109 HydrophobicContact CB-CD1 4.37Å; L96-Y109 HydrophobicContact CB-CD2 3.88Å; L96-Y109 HydrophobicContact CB-CE1 4.32Å; L96-Y109 HydrophobicContact CB-CE2 3.8Å; L96-Y109 HydrophobicContact CB-CG 4.18Å; L96-Y109 HydrophobicContact CD1-CD2 3.89Å; L96-Y109 HydrophobicContact CD1-CE2 4.47Å; L96-Y109 HydrophobicContact CD1-CG 4.33Å; L96-Y109 HydrophobicContact CG-CD2 4.42Å; G97-Y109 WeakPolarHBondContact CA-OH 3.3Å; G97-Y109 PolarHBondContact N-OH 3.18Å; I100-Y109 HydrophobicContact CB-CD1 3.85Å; I100-Y109 HydrophobicContact CB-CE1 3.91Å; I100-Y109 HydrophobicContact CD1-CD1 3.9Å; I100-Y109 HydrophobicContact CG1-CD1 4.45Å; I100-Y109 HydrophobicContact CG2-CD1 4Å; I100-Y109 HydrophobicContact CG2-CE1 4.22Å; I100-Y109 WeakPolarHBondContact O-CE1 3.43Å; A105-Y109 HydrophobicContact CB-CE2 4.43Å; A105-Y109 WeakPolarHBondContact O-CD1 3.41Å; A105-Y109 VanDerWaalsContact O-CD2 3.31Å; A105-Y109 WeakPolarHBondContact O-CD2 3.33Å; A105-Y109 PolarHBondContact O-N 2.91Å; Y107-Y109 VanDerWaalsContact C-N 3.35Å; Y107-Y109 PolarHBondContact O-N 3.32Å; Y109-S113 VanDerWaalsContact O-CB 3.29Å; Y109-S113 WeakPolarHBondContact O-CB 3.39Å; Y109-S113 PolarHBondContact O-N 3.41Å; Y109-S113 PolarHBondContact O-OG 2.77Å; Y109-N249 HydrophobicContact CE2-CB 4.46Å; Y109-N249 WeakPolarHBondContact OH-CB 3.09Å; Y109-N249 PolarHBondContact OH-ND2 2.77Å
110	I	93.6	Very high	87.6	Confident	0 Å²	0	28.4 Å²	28.4	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-67.5	-40.7	175.9	-71.1	170.1	0	0	0	110.7	S106 Y107 E112 S113 F114 G115 I118 A119 R122 F395 L398 S399	S106-I110 WeakPolarHBondContact O-CB 3.26Å; S106-I110 WeakPolarHBondContact O-CD1 3.29Å; S106-I110 VanDerWaalsContact O-CG1 3.26Å; S106-I110 WeakPolarHBondContact O-CG1 3.38Å; S106-I110 PolarHBondContact O-N 3.04Å; Y107-I110 PolarHBondContact O-N 2.84Å; I110-E112 PolarHBondContact O-N 2.76Å; I110-S113 PolarHBondContact O-N 3.17Å; I110-F114 HydrophobicContact CG2-CD2 4.31Å; I110-F114 PolarHBondContact O-N 3.21Å; I110-G115 PolarHBondContact O-N 3.07Å; I110-I118 HydrophobicContact CG2-CB 3.94Å; I110-I118 HydrophobicContact CG2-CG2 3.52Å; I110-A119 HydrophobicContact CG2-CB 4.22Å; I110-R122 HydrophobicContact CD1-CB 3.99Å; I110-R122 HydrophobicContact CD1-CG 3.86Å; I110-F395 HydrophobicContact CD1-CD1 4.1Å; I110-L398 HydrophobicContact CD1-CD2 4.29Å; I110-L398 HydrophobicContact CD1-CG 4.45Å; I110-S399 WeakPolarHBondContact CD1-OG 3.41Å
111	L	91.5	Very high	87.9	Confident	38 Å²	38	29.2 Å²	29.2	20%	0.199	16%	0.162	C	C	.	.	H	α-helix	trans	-59	-47	177.4	-178.7	60.6	0	0	0	111.9	Y107 A108 G115 A119	Y107-L111 HydrophobicContact CE1-CD2 4.23Å; Y107-L111 VanDerWaalsContact O-CB 3.29Å; Y107-L111 WeakPolarHBondContact O-CB 3.48Å; Y107-L111 PolarHBondContact O-N 3.26Å; A108-L111 PolarHBondContact O-N 3.47Å; L111-G115 VanDerWaalsContact O-CA 3.24Å; L111-G115 WeakPolarHBondContact O-CA 3.22Å; L111-G115 PolarHBondContact O-N 3.48Å; L111-G115 VanDerWaalsContact O-N 3.07Å; L111-A119 HydrophobicContact CB-CB 3.72Å; L111-A119 HydrophobicContact CD1-CB 3.78Å; L111-A119 HydrophobicContact CG-CB 4.34Å
112	E	91	Very high	88.6	Confident	60 Å²	60	25.9 Å²	25.9	28%	0.28	14%	0.14	S	C	.	.	H	α-helix	trans	-69.1	-32.8	179.1	-170.1	80.7	-178.6	0	0	112.5	I100 K102 A108 I110 R413	I100-E112 HydrophobicContact CD1-CB 4.03Å; I100-E112 HydrophobicContact CD1-CG 4Å; I100-E112 HydrophobicContact CG1-CG 4.43Å; K102-E112 IonicContact NZ-OE2 3.74Å; K102-E112 PolarHBondContact NZ-OE2 3.25Å; A108-E112 WeakPolarHBondContact O-CB 3.41Å; A108-E112 PolarHBondContact O-N 3.03Å; I110-E112 PolarHBondContact O-N 2.76Å; E112-R413 IonicContact OE1-CZ 2.74Å; E112-R413 IonicContact OE1-NH1 2.74Å; E112-R413 PolarHBondContact OE1-NH1 3.38Å; E112-R413 IonicContact OE1-NH2 3.82Å; E112-R413 PolarHBondContact OE1-NH2 3Å; E112-R413 VanDerWaalsContact OE1-NH2 3.14Å
113	S	92.7	Very high	89.3	Confident	7 Å²	7	20.8 Å²	20.8	5%	0.049	12%	0.118	C	C	.	.	H	α-helix	trans	-85.7	-49.8	-175.8	-54.5	0	0	0	0	113.1	Y109 I110 Y405 L406	Y109-S113 VanDerWaalsContact O-CB 3.29Å; Y109-S113 WeakPolarHBondContact O-CB 3.39Å; Y109-S113 PolarHBondContact O-N 3.41Å; Y109-S113 PolarHBondContact O-OG 2.77Å; I110-S113 PolarHBondContact O-N 3.17Å; S113-Y405 WeakPolarHBondContact O-CE1 3.33Å; S113-L406 WeakPolarHBondContact OG-CD1 3.47Å
114	F	93.6	Very high	90.4	Very high	77 Å²	77	21 Å²	21	34%	0.338	11%	0.113	S	C	.	.	H	α-helix	trans	-115.3	-6.5	-169.4	-58.9	-69.1	0	0	0	113.9	I110 I118 L398	I110-F114 HydrophobicContact CG2-CD2 4.31Å; I110-F114 PolarHBondContact O-N 3.21Å; F114-I118 HydrophobicContact CB-CB 3.97Å; F114-I118 HydrophobicContact CB-CG1 3.96Å; F114-I118 HydrophobicContact CB-CG2 4.3Å; F114-L398 HydrophobicContact CD2-CD1 4.29Å; F114-L398 HydrophobicContact CD2-CG 4.32Å; F114-L398 HydrophobicContact CE2-CD1 3.75Å; F114-L398 HydrophobicContact CE2-CG 3.98Å; F114-L398 WeakPolarHBondContact CE2-O 3.41Å; F114-L398 HydrophobicContact CZ-CD1 4Å
115	G	91.2	Very high	91.5	Very high	29 Å²	29	20.8 Å²	20.8	30%	0.299	11%	0.11	S	C	.	.			trans	88.5	-177.8	177.8	0	0	0	0	0	114.7	I110 L111 F117 A119	I110-G115 PolarHBondContact O-N 3.07Å; L111-G115 VanDerWaalsContact O-CA 3.24Å; L111-G115 WeakPolarHBondContact O-CA 3.22Å; L111-G115 PolarHBondContact O-N 3.48Å; L111-G115 VanDerWaalsContact O-N 3.07Å; G115-F117 PolarHBondContact O-N 2.89Å; G115-A119 WeakPolarHBondContact O-CB 3.45Å; G115-A119 PolarHBondContact O-N 2.77Å
116	G	90	Very high	91.9	Very high	20 Å²	20	20.8 Å²	20.8	21%	0.206	11%	0.11	C	C	.	.	H	α-helix	trans	-63.5	-34.3	-168	0	0	0	0	0	115.4	A119 F120 H346	G116-A119 PolarHBondContact O-N 3.41Å; G116-F120 WeakPolarHBondContact O-CB 3.48Å; G116-F120 PolarHBondContact O-N 2.93Å; G116-H346 PolarHBondContact O-CE1 2.91Å
117	F	92.8	Very high	92.1	Very high	68 Å²	68	21 Å²	21	30%	0.298	11%	0.111	S	C	.	.	H	α-helix	trans	-63.1	-53.6	-178.2	174.5	-115	0	0	0	112.5	G115 A119 F120 I121 V457 Y460 F461	G115-F117 PolarHBondContact O-N 2.89Å; F117-A119 VanDerWaalsContact C-N 3.29Å; F117-A119 PolarHBondContact O-N 2.97Å; F117-F120 WeakPolarHBondContact O-CB 3.36Å; F117-F120 PolarHBondContact O-N 2.86Å; F117-I121 HydrophobicContact CE2-CD1 4.3Å; F117-I121 HydrophobicContact CE2-CG1 4.19Å; F117-I121 HydrophobicContact CZ-CG1 4.24Å; F117-I121 WeakPolarHBondContact O-CG1 3.35Å; F117-I121 PolarHBondContact O-N 3.44Å; F117-V457 HydrophobicContact CE2-CG1 4.32Å; F117-V457 HydrophobicContact CE2-CG2 4.27Å; F117-V457 HydrophobicContact CZ-CG1 4.34Å; F117-V457 HydrophobicContact CZ-CG2 3.96Å; F117-Y460 HydrophobicContact CB-CE1 3.96Å; F117-Y460 AromaticContact CD2-CD1 3.42Å; F117-Y460 HydrophobicContact CD2-CD1 3.42Å; F117-Y460 VanDerWaalsContact CD2-CD1 3.42Å; F117-Y460 HydrophobicContact CD2-CD2 4.44Å; F117-Y460 AromaticContact CD2-CE1 3.65Å; F117-Y460 HydrophobicContact CD2-CE1 3.65Å; F117-Y460 AromaticContact CD2-CG 3.83Å; F117-Y460 HydrophobicContact CD2-CG 3.83Å; F117-Y460 HydrophobicContact CE2-CD1 4.06Å; F117-Y460 HydrophobicContact CE2-CG 4.38Å; F117-Y460 HydrophobicContact CG-CD1 4.45Å; F117-Y460 HydrophobicContact CG-CE1 4.26Å; F117-Y460 PolarHBondContact N-OH 3.15Å; F117-F461 HydrophobicContact CE2-CE2 4.38Å
118	I	94.1	Very high	92.3	Very high	50 Å²	50	22.1 Å²	22.1	26%	0.256	12%	0.118	S	C	.	.	H	α-helix	trans	-67.9	-35.2	-178.9	-54.9	-60.4	0	0	0	110.6	I110 F114 I121 R122 L398	I110-I118 HydrophobicContact CG2-CB 3.94Å; I110-I118 HydrophobicContact CG2-CG2 3.52Å; F114-I118 HydrophobicContact CB-CB 3.97Å; F114-I118 HydrophobicContact CB-CG1 3.96Å; F114-I118 HydrophobicContact CB-CG2 4.3Å; I118-I121 PolarHBondContact O-N 3.18Å; I118-R122 PolarHBondContact O-N 3.26Å; I118-L398 HydrophobicContact CG2-CD2 3.47Å; I118-L398 VanDerWaalsContact CG2-CD2 3.47Å
119	A	92.5	Very high	92.6	Very high	0 Å²	0	22 Å²	22	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-63	-40.4	173.5	0	0	0	0	0	112.3	Y107 I110 L111 G115 G116 F117 R122 L123	Y107-A119 HydrophobicContact CD2-CB 4.05Å; Y107-A119 WeakPolarHBondContact CD2-O 3.32Å; Y107-A119 HydrophobicContact CE2-CB 3.74Å; Y107-A119 WeakPolarHBondContact CE2-O 3.31Å; I110-A119 HydrophobicContact CG2-CB 4.22Å; L111-A119 HydrophobicContact CB-CB 3.72Å; L111-A119 HydrophobicContact CD1-CB 3.78Å; L111-A119 HydrophobicContact CG-CB 4.34Å; G115-A119 WeakPolarHBondContact O-CB 3.45Å; G115-A119 PolarHBondContact O-N 2.77Å; G116-A119 PolarHBondContact O-N 3.41Å; F117-A119 VanDerWaalsContact C-N 3.29Å; F117-A119 PolarHBondContact O-N 2.97Å; A119-R122 WeakPolarHBondContact O-CB 3.5Å; A119-R122 PolarHBondContact O-N 3.26Å; A119-L123 WeakPolarHBondContact O-CB 3.5Å; A119-L123 PolarHBondContact O-N 2.92Å
120	F	93.1	Very high	92.6	Very high	3 Å²	3	22 Å²	22	1%	0.013	12%	0.116	C	C	.	.	H	α-helix	trans	-61.8	-46.3	172.9	172.9	-84.8	0	0	0	111.2	G116 F117 R122 L123 W124 H346 G456 V459 Y460 V464	G116-F120 WeakPolarHBondContact O-CB 3.48Å; G116-F120 PolarHBondContact O-N 2.93Å; F117-F120 WeakPolarHBondContact O-CB 3.36Å; F117-F120 PolarHBondContact O-N 2.86Å; F120-R122 VanDerWaalsContact C-N 3.28Å; F120-R122 PolarHBondContact O-N 3.39Å; F120-L123 WeakPolarHBondContact O-CB 3.48Å; F120-L123 PolarHBondContact O-N 3.14Å; F120-L123 VanDerWaalsContact O-N 3.07Å; F120-W124 HydrophobicContact CD1-CB 4.39Å; F120-W124 HydrophobicContact CE1-CB 3.98Å; F120-W124 HydrophobicContact CE1-CD2 4.32Å; F120-W124 HydrophobicContact CE1-CE3 4.35Å; F120-W124 HydrophobicContact CE1-CG 4.19Å; F120-W124 HydrophobicContact CZ-CB 4.36Å; F120-W124 HydrophobicContact CZ-CD2 4.19Å; F120-W124 AromaticContact CZ-CE3 3.77Å; F120-W124 HydrophobicContact CZ-CE3 3.77Å; F120-W124 HydrophobicContact CZ-CG 4.47Å; F120-W124 HydrophobicContact CZ-CZ3 4.45Å; F120-W124 VanDerWaalsContact O-CB 3.28Å; F120-W124 WeakPolarHBondContact O-CB 3.36Å; F120-W124 PolarHBondContact O-N 2.92Å; F120-H346 HydrophobicContact CD2-CB 4.01Å; F120-H346 WeakPolarHBondContact CD2-O 3.23Å; F120-H346 WeakPolarHBondContact CE2-O 3.27Å; F120-G456 WeakPolarHBondContact CE1-O 3.23Å; F120-V459 HydrophobicContact CZ-CB 4.19Å; F120-V459 HydrophobicContact CZ-CG1 3.93Å; F120-Y460 HydrophobicContact CB-CD2 3.47Å; F120-Y460 VanDerWaalsContact CB-CD2 3.47Å; F120-Y460 HydrophobicContact CB-CE2 3.79Å; F120-Y460 HydrophobicContact CB-CG 4.49Å; F120-Y460 AromaticContact CD1-CD2 3.76Å; F120-Y460 HydrophobicContact CD1-CD2 3.76Å; F120-Y460 HydrophobicContact CD1-CG 4.12Å; F120-Y460 AromaticContact CD2-CD2 3.84Å; F120-Y460 HydrophobicContact CD2-CD2 3.84Å; F120-Y460 AromaticContact CG-CD2 3.4Å; F120-Y460 HydrophobicContact CG-CD2 3.4Å; F120-Y460 HydrophobicContact CG-CE2 4.2Å; F120-Y460 HydrophobicContact CG-CG 4.22Å; F120-V464 HydrophobicContact CD2-CG2 4.02Å; F120-V464 HydrophobicContact CE2-CG2 4.09Å
121	I	94.4	Very high	92.5	Very high	20 Å²	20	23.5 Å²	23.5	10%	0.103	12%	0.123	C	C	.	.	H	α-helix	trans	-62.5	-38.1	179.6	-61.5	-64.9	0	0	0	111.1	F117 I118 T125 F395 A453 V457	F117-I121 HydrophobicContact CE2-CD1 4.3Å; F117-I121 HydrophobicContact CE2-CG1 4.19Å; F117-I121 HydrophobicContact CZ-CG1 4.24Å; F117-I121 WeakPolarHBondContact O-CG1 3.35Å; F117-I121 PolarHBondContact O-N 3.44Å; I118-I121 PolarHBondContact O-N 3.18Å; I121-T125 WeakPolarHBondContact O-CB 3.31Å; I121-T125 PolarHBondContact O-N 3.47Å; I121-T125 PolarHBondContact O-OG1 3.02Å; I121-F395 HydrophobicContact CG2-CE1 4.44Å; I121-F395 HydrophobicContact CG2-CZ 4.03Å; I121-A453 HydrophobicContact CG2-CB 4.42Å; I121-V457 HydrophobicContact CD1-CG2 3.93Å
122	R	93.3	Very high	92.7	Very high	7 Å²	7	21.7 Å²	21.7	3%	0.026	11%	0.113	C	C	.	.	H	α-helix	trans	-58.9	-47.1	170.8	169.7	65.3	-174.6	72.4	-5.5	112.1	I110 I118 A119 F120 S126 F395	I110-R122 HydrophobicContact CD1-CB 3.99Å; I110-R122 HydrophobicContact CD1-CG 3.86Å; I118-R122 PolarHBondContact O-N 3.26Å; A119-R122 WeakPolarHBondContact O-CB 3.5Å; A119-R122 PolarHBondContact O-N 3.26Å; F120-R122 VanDerWaalsContact C-N 3.28Å; F120-R122 PolarHBondContact O-N 3.39Å; R122-S126 PolarHBondContact NH1-OG 2.95Å; R122-S126 PolarHBondContact NH2-OG 2.93Å; R122-S126 PolarHBondContact O-N 3.33Å; R122-F395 VanDerWaalsContact CA-CE1 3.5Å; R122-F395 HydrophobicContact CB-CD1 3.79Å; R122-F395 HydrophobicContact CB-CE1 3.78Å; R122-F395 HydrophobicContact CB-CG 4.42Å; R122-F395 HydrophobicContact CB-CZ 4.44Å; R122-F395 HydrophobicContact CG-CD1 4.17Å; R122-F395 HydrophobicContact CG-CG 4.39Å
123	L	92.1	Very high	92.8	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-66.6	-46.2	-178.9	179.7	65.1	0	0	0	111.3	Y107 A119 F120 T125 S126 L127 L337 G341 H346 L347	Y107-L123 HydrophobicContact CD2-CB 3.94Å; Y107-L123 HydrophobicContact CE2-CB 4.01Å; Y107-L123 HydrophobicContact CE2-CD2 4.09Å; A119-L123 WeakPolarHBondContact O-CB 3.5Å; A119-L123 PolarHBondContact O-N 2.92Å; F120-L123 WeakPolarHBondContact O-CB 3.48Å; F120-L123 PolarHBondContact O-N 3.14Å; F120-L123 VanDerWaalsContact O-N 3.07Å; L123-T125 VanDerWaalsContact C-N 3.34Å; L123-T125 PolarHBondContact O-N 3.41Å; L123-S126 WeakPolarHBondContact O-CB 3.4Å; L123-S126 PolarHBondContact O-N 3.46Å; L123-L127 WeakPolarHBondContact O-CB 3.47Å; L123-L127 PolarHBondContact O-N 3.43Å; L123-L337 HydrophobicContact CD1-CD1 3.99Å; L123-L337 HydrophobicContact CD1-CD2 4.38Å; L123-L337 HydrophobicContact CD1-CG 3.83Å; L123-G341 VanDerWaalsContact CD2-CA 3.48Å; L123-H346 HydrophobicContact CD2-CB 3.95Å; L123-L347 HydrophobicContact CD1-CD1 4.27Å; L123-L347 HydrophobicContact CD2-CD1 3.75Å; L123-L347 HydrophobicContact CD2-CD2 4.41Å; L123-L347 HydrophobicContact CD2-CG 3.73Å; L123-L347 HydrophobicContact CG-CD1 4.05Å; L123-L347 HydrophobicContact CG-CG 4.35Å
124	W	93.7	Very high	92.9	Very high	46 Å²	46	19.2 Å²	19.2	17%	0.174	10%	0.103	C	C	.	.	H	α-helix	trans	-56	-47.1	175.9	-174.3	-104.5	0	0	0	111.6	F120 L127 L128 I452 S455 G456 V459	F120-W124 HydrophobicContact CD1-CB 4.39Å; F120-W124 HydrophobicContact CE1-CB 3.98Å; F120-W124 HydrophobicContact CE1-CD2 4.32Å; F120-W124 HydrophobicContact CE1-CE3 4.35Å; F120-W124 HydrophobicContact CE1-CG 4.19Å; F120-W124 HydrophobicContact CZ-CB 4.36Å; F120-W124 HydrophobicContact CZ-CD2 4.19Å; F120-W124 AromaticContact CZ-CE3 3.77Å; F120-W124 HydrophobicContact CZ-CE3 3.77Å; F120-W124 HydrophobicContact CZ-CG 4.47Å; F120-W124 HydrophobicContact CZ-CZ3 4.45Å; F120-W124 VanDerWaalsContact O-CB 3.28Å; F120-W124 WeakPolarHBondContact O-CB 3.36Å; F120-W124 PolarHBondContact O-N 2.92Å; W124-L127 PolarHBondContact O-N 3.22Å; W124-L128 HydrophobicContact CD2-CD1 4.07Å; W124-L128 HydrophobicContact CG-CD1 4.46Å; W124-L128 HydrophobicContact CH2-CD1 4.33Å; W124-L128 HydrophobicContact CZ2-CD1 3.53Å; W124-L128 PolarHBondContact O-N 2.83Å; W124-I452 PolarHBondContact NE1-O 3.27Å; W124-S455 PolarHBondContact NE1-OG 3.46Å; W124-S455 VanDerWaalsContact NE1-OG 3.13Å; W124-G456 VanDerWaalsContact CD1-CA 3.44Å; W124-V459 HydrophobicContact CH2-CB 4.35Å; W124-V459 HydrophobicContact CH2-CG1 4.02Å; W124-V459 HydrophobicContact CH2-CG2 3.93Å; W124-V459 HydrophobicContact CZ2-CG2 3.97Å; W124-V459 HydrophobicContact CZ3-CG1 3.91Å
125	T	93.7	Very high	92.9	Very high	1 Å²	1	15.5 Å²	15.5	1%	0.006	9%	0.087	C	C	.	.	H	α-helix	trans	-69.7	-34	178.9	-48.2	0	0	0	0	112.1	I121 L123 L127 I129 I130 F395	I121-T125 WeakPolarHBondContact O-CB 3.31Å; I121-T125 PolarHBondContact O-N 3.47Å; I121-T125 PolarHBondContact O-OG1 3.02Å; L123-T125 VanDerWaalsContact C-N 3.34Å; L123-T125 PolarHBondContact O-N 3.41Å; T125-L127 VanDerWaalsContact C-N 3.33Å; T125-I129 HydrophobicContact CG2-CB 4.25Å; T125-I129 HydrophobicContact CG2-CD1 3.77Å; T125-I129 HydrophobicContact CG2-CG1 4.15Å; T125-I129 WeakPolarHBondContact O-CA 3.43Å; T125-I129 WeakPolarHBondContact O-CB 3.2Å; T125-I129 PolarHBondContact O-N 3.26Å; T125-I130 PolarHBondContact O-N 3.36Å; T125-I130 VanDerWaalsContact O-N 3.16Å; T125-F395 VanDerWaalsContact CB-CE2 3.46Å; T125-F395 HydrophobicContact CG2-CD2 4.48Å; T125-F395 HydrophobicContact CG2-CE2 3.69Å; T125-F395 WeakPolarHBondContact OG1-CE2 3.31Å
126	S	91.9	Very high	93.2	Very high	0 Å²	0	14.1 Å²	14.1	0%	0	7%	0.072	C	C	.	.	I	π-helix	trans	-60.6	-48.1	171.9	-118.2	0	0	0	0	111.3	R122 L123 L128 I130 E131	R122-S126 PolarHBondContact NH1-OG 2.95Å; R122-S126 PolarHBondContact NH2-OG 2.93Å; R122-S126 PolarHBondContact O-N 3.33Å; L123-S126 WeakPolarHBondContact O-CB 3.4Å; L123-S126 PolarHBondContact O-N 3.46Å; S126-L128 PolarHBondContact O-N 3.08Å; S126-I130 PolarHBondContact O-N 2.59Å; S126-E131 WeakPolarHBondContact O-CG 3.35Å; S126-E131 PolarHBondContact O-N 3.11Å; S126-E131 PolarHBondContact OG-OE1 3.46Å; S126-E131 VanDerWaalsContact OG-OE1 3.1Å
127	L	91.2	Very high	93.4	Very high	4 Å²	4	13.2 Å²	13.2	2%	0.021	6%	0.063	C	C	.	.	I	π-helix	trans	-66.7	-36.3	-174.5	179.4	149.7	0	0	0	112.5	L123 W124 T125 P132 F338 L347 L351 F367	L123-L127 WeakPolarHBondContact O-CB 3.47Å; L123-L127 PolarHBondContact O-N 3.43Å; W124-L127 PolarHBondContact O-N 3.22Å; T125-L127 VanDerWaalsContact C-N 3.33Å; L127-P132 VanDerWaalsContact O-CG 3.29Å; L127-P132 WeakPolarHBondContact O-CG 3.48Å; L127-F338 HydrophobicContact CB-CD1 4.24Å; L127-F338 HydrophobicContact CB-CE1 3.59Å; L127-F338 HydrophobicContact CB-CZ 3.98Å; L127-F338 HydrophobicContact CD1-CD1 3.87Å; L127-F338 HydrophobicContact CD1-CD2 4.43Å; L127-F338 HydrophobicContact CD1-CE1 3.96Å; L127-F338 HydrophobicContact CD1-CE2 4.47Å; L127-F338 HydrophobicContact CD1-CG 4.15Å; L127-F338 HydrophobicContact CD1-CZ 4.27Å; L127-F338 HydrophobicContact CG-CD1 4.27Å; L127-F338 HydrophobicContact CG-CE1 3.83Å; L127-F338 HydrophobicContact CG-CE2 4.36Å; L127-F338 HydrophobicContact CG-CZ 3.88Å; L127-L347 HydrophobicContact CD1-CD1 3.92Å; L127-L347 HydrophobicContact CD1-CD2 3.96Å; L127-L351 HydrophobicContact CD1-CD1 4.23Å; L127-F367 HydrophobicContact CD1-CE1 4.12Å; L127-F367 HydrophobicContact CD2-CD1 4.27Å; L127-F367 HydrophobicContact CD2-CE1 3.18Å; L127-F367 HydrophobicContact CD2-CE2 4.48Å; L127-F367 HydrophobicContact CD2-CZ 3.32Å; L127-F367 HydrophobicContact CG-CD1 4.22Å; L127-F367 HydrophobicContact CG-CE1 3.48Å; L127-F367 VanDerWaalsContact CG-CE1 3.48Å; L127-F367 HydrophobicContact CG-CZ 4.14Å
128	L	93	Very high	93.5	Very high	28 Å²	28	10.6 Å²	10.6	15%	0.147	5%	0.052	C	C	.	.	I	π-helix	trans	-96.3	-24.4	-177.8	-67.5	-176.9	0	0	0	115.2	W124 S126 F367 M371 Y375 I452	W124-L128 HydrophobicContact CD2-CD1 4.07Å; W124-L128 HydrophobicContact CG-CD1 4.46Å; W124-L128 HydrophobicContact CH2-CD1 4.33Å; W124-L128 HydrophobicContact CZ2-CD1 3.53Å; W124-L128 PolarHBondContact O-N 2.83Å; S126-L128 PolarHBondContact O-N 3.08Å; L128-F367 HydrophobicContact CD2-CZ 4.16Å; L128-M371 HydrophobicContact CD2-CE 3.75Å; L128-M371 HydrophobicContact CD2-SD 4.16Å; L128-Y375 WeakPolarHBondContact O-CE2 3.14Å; L128-Y375 PolarHBondContact O-OH 3.35Å; L128-I452 HydrophobicContact CB-CG2 3.89Å; L128-I452 HydrophobicContact CD1-CG2 3.9Å
129	I	93	Very high	93.6	Very high	2 Å²	2	8.2 Å²	8.2	1%	0.01	4%	0.04	C	C	.	.	I	π-helix	trans	-123.9	-64.8	-174.3	-49.5	-177.3	0	0	0	110.6	T125 E131 P132 T133 I452	T125-I129 HydrophobicContact CG2-CB 4.25Å; T125-I129 HydrophobicContact CG2-CD1 3.77Å; T125-I129 HydrophobicContact CG2-CG1 4.15Å; T125-I129 WeakPolarHBondContact O-CA 3.43Å; T125-I129 WeakPolarHBondContact O-CB 3.2Å; T125-I129 PolarHBondContact O-N 3.26Å; I129-E131 PolarHBondContact O-N 3.44Å; I129-P132 WeakPolarHBondContact O-CD 3.33Å; I129-T133 WeakPolarHBondContact O-CB 3.39Å; I129-T133 PolarHBondContact O-N 3.27Å; I129-T133 PolarHBondContact O-OG1 3.45Å; I129-I452 HydrophobicContact CD1-CB 3.76Å; I129-I452 HydrophobicContact CD1-CD1 4.08Å; I129-I452 HydrophobicContact CD1-CG2 3.65Å; I129-I452 HydrophobicContact CG1-CB 4.29Å; I129-I452 HydrophobicContact CG1-CD1 4.23Å; I129-I452 HydrophobicContact CG1-CG2 3.68Å
130	I	92.5	Very high	93.7	Very high	3 Å²	3	8.4 Å²	8.4	2%	0.015	4%	0.04	C	C	.	.	I	π-helix	trans	-62.5	-53.9	-163.1	-55.4	175.8	0	0	0	111.5	T125 S126 S134 Y388 Y392 F395	T125-I130 PolarHBondContact O-N 3.36Å; T125-I130 VanDerWaalsContact O-N 3.16Å; S126-I130 PolarHBondContact O-N 2.59Å; I130-S134 VanDerWaalsContact O-CB 3.32Å; I130-S134 WeakPolarHBondContact O-CB 3.41Å; I130-S134 PolarHBondContact O-N 3.37Å; I130-S134 VanDerWaalsContact O-N 3.16Å; I130-Y388 HydrophobicContact CB-CD2 4.44Å; I130-Y388 HydrophobicContact CG2-CD2 3.7Å; I130-Y388 HydrophobicContact CG2-CE2 3.42Å; I130-Y388 VanDerWaalsContact CG2-CE2 3.42Å; I130-Y388 WeakPolarHBondContact O-CD2 3.35Å; I130-Y392 HydrophobicContact CG2-CD2 4.1Å; I130-F395 HydrophobicContact CD1-CD2 4.41Å
131	E	92.1	Very high	93.7	Very high	30 Å²	30	8.3 Å²	8.3	14%	0.14	4%	0.04	C	C	.	.	H	α-helix	trans	-68.2	-50.9	-175.9	-49	-56.5	150.1	0	0	112.1	S126 I129 T133 S134 Q135 A334 F338	S126-E131 WeakPolarHBondContact O-CG 3.35Å; S126-E131 PolarHBondContact O-N 3.11Å; S126-E131 PolarHBondContact OG-OE1 3.46Å; S126-E131 VanDerWaalsContact OG-OE1 3.1Å; I129-E131 PolarHBondContact O-N 3.44Å; E131-T133 PolarHBondContact O-N 2.87Å; E131-S134 PolarHBondContact O-N 2.93Å; E131-Q135 VanDerWaalsContact O-CG 3.26Å; E131-Q135 WeakPolarHBondContact O-CG 3.31Å; E131-Q135 PolarHBondContact O-N 3.13Å; E131-Q135 PolarHBondContact O-NE2 3.39Å; E131-A334 HydrophobicContact CB-CB 3.87Å; E131-A334 HydrophobicContact CG-CB 3.86Å; E131-F338 HydrophobicContact CG-CE1 4.39Å; E131-F338 HydrophobicContact CG-CZ 4.34Å
132	P	94.4	Very high	93.6	Very high	0 Å²	0	8.7 Å²	8.7	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-66.4	-36.8	-176.5	-23.4	36.7	0	0	0	113.3	L127 I129 Q135 A136 M371 Y375	L127-P132 VanDerWaalsContact O-CG 3.29Å; L127-P132 WeakPolarHBondContact O-CG 3.48Å; I129-P132 WeakPolarHBondContact O-CD 3.33Å; P132-Q135 PolarHBondContact O-N 2.84Å; P132-A136 WeakPolarHBondContact O-CB 3.42Å; P132-A136 PolarHBondContact O-N 2.91Å; P132-M371 HydrophobicContact CB-CB 3.71Å; P132-M371 HydrophobicContact CG-CB 3.55Å; P132-M371 HydrophobicContact CG-CG 4.39Å; P132-Y375 HydrophobicContact CB-CD2 3.63Å; P132-Y375 HydrophobicContact CB-CE2 3.88Å
133	T	94.6	Very high	93.7	Very high	0 Å²	0	8.3 Å²	8.3	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-67.5	-44.5	179.2	-57.3	0	0	0	0	110.9	I129 E131 Q135 A136 V137 Y375 L384	I129-T133 WeakPolarHBondContact O-CB 3.39Å; I129-T133 PolarHBondContact O-N 3.27Å; I129-T133 PolarHBondContact O-OG1 3.45Å; E131-T133 PolarHBondContact O-N 2.87Å; T133-Q135 VanDerWaalsContact C-N 3.34Å; T133-Q135 PolarHBondContact O-N 2.9Å; T133-A136 PolarHBondContact O-N 3.22Å; T133-V137 WeakPolarHBondContact O-CG2 3.39Å; T133-V137 PolarHBondContact O-N 2.99Å; T133-Y375 WeakPolarHBondContact OG1-CE1 3.47Å; T133-L384 HydrophobicContact CG2-CB 3.67Å; T133-L384 HydrophobicContact CG2-CD2 3.94Å; T133-L384 HydrophobicContact CG2-CG 4.4Å; T133-L384 WeakPolarHBondContact CG2-O 3.45Å
134	S	93.3	Very high	93.7	Very high	15 Å²	15	9.3 Å²	9.3	11%	0.105	5%	0.045	C	C	.	.	H	α-helix	trans	-59.9	-44.9	175.6	-177.8	0	0	0	0	111.5	I130 E131 A136 V137 I138	I130-S134 VanDerWaalsContact O-CB 3.32Å; I130-S134 WeakPolarHBondContact O-CB 3.41Å; I130-S134 PolarHBondContact O-N 3.37Å; I130-S134 VanDerWaalsContact O-N 3.16Å; E131-S134 PolarHBondContact O-N 2.93Å; S134-A136 PolarHBondContact O-N 3.15Å; S134-V137 PolarHBondContact O-N 2.99Å; S134-I138 WeakPolarHBondContact O-CD1 3.03Å; S134-I138 VanDerWaalsContact O-CG1 3.24Å; S134-I138 WeakPolarHBondContact O-CG1 3.16Å; S134-I138 PolarHBondContact O-N 2.91Å
135	Q	94.9	Very high	93.6	Very high	0 Å²	0	7.1 Å²	7.1	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-63.1	-41.2	177.3	-70.3	167.9	41.4	0	0	112.4	E131 P132 T133 I138 A139 L327 S330 I331 N368 S372	E131-Q135 VanDerWaalsContact O-CG 3.26Å; E131-Q135 WeakPolarHBondContact O-CG 3.31Å; E131-Q135 PolarHBondContact O-N 3.13Å; E131-Q135 PolarHBondContact O-NE2 3.39Å; P132-Q135 PolarHBondContact O-N 2.84Å; T133-Q135 VanDerWaalsContact C-N 3.34Å; T133-Q135 PolarHBondContact O-N 2.9Å; Q135-I138 PolarHBondContact O-N 3Å; Q135-A139 VanDerWaalsContact O-CB 3.28Å; Q135-A139 WeakPolarHBondContact O-CB 3.33Å; Q135-A139 PolarHBondContact O-N 3.01Å; Q135-L327 HydrophobicContact CB-CD1 3.66Å; Q135-L327 HydrophobicContact CG-CD1 3.88Å; Q135-S330 WeakPolarHBondContact CG-OG 3.24Å; Q135-S330 PolarHBondContact NE2-OG 3.09Å; Q135-I331 HydrophobicContact CG-CG1 4.48Å; Q135-N368 PolarHBondContact NE2-ND2 3.34Å; Q135-N368 PolarHBondContact NE2-OD1 3.26Å; Q135-N368 VanDerWaalsContact NE2-OD1 3.13Å; Q135-N368 PolarHBondContact OE1-ND2 3.24Å; Q135-N368 PolarHBondContact OE1-OD1 2.71Å; Q135-S372 PolarHBondContact OE1-OG 2.73Å; Q135-S372 VanDerWaalsContact OE1-OG 3.05Å
136	A	96.2	Very high	93.5	Very high	0 Å²	0	11 Å²	11	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-60.9	-47.3	174.7	0	0	0	0	0	111.4	P132 T133 S134 I138 A139 I140 L376 L384	P132-A136 WeakPolarHBondContact O-CB 3.42Å; P132-A136 PolarHBondContact O-N 2.91Å; T133-A136 PolarHBondContact O-N 3.22Å; S134-A136 PolarHBondContact O-N 3.15Å; A136-I138 PolarHBondContact O-N 3.24Å; A136-A139 PolarHBondContact O-N 2.53Å; A136-I140 VanDerWaalsContact O-CD1 3.29Å; A136-I140 WeakPolarHBondContact O-CD1 3.3Å; A136-I140 WeakPolarHBondContact O-CG1 3.25Å; A136-I140 PolarHBondContact O-N 3.44Å; A136-L376 HydrophobicContact CB-CD2 4.06Å; A136-L384 HydrophobicContact CB-CD1 4.11Å
137	V	95.1	Very high	93.5	Very high	0 Å²	0	11.4 Å²	11.4	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-59.2	-46.8	177	173.9	0	0	0	0	111.2	T133 S134 A139 I140 T141 F240 V381 L384 I385	T133-V137 WeakPolarHBondContact O-CG2 3.39Å; T133-V137 PolarHBondContact O-N 2.99Å; S134-V137 PolarHBondContact O-N 2.99Å; V137-A139 VanDerWaalsContact C-N 3.34Å; V137-A139 PolarHBondContact O-N 3.34Å; V137-I140 PolarHBondContact O-N 3.46Å; V137-T141 PolarHBondContact O-N 3.5Å; V137-T141 PolarHBondContact O-OG1 2.96Å; V137-F240 HydrophobicContact CB-CZ 3.93Å; V137-F240 HydrophobicContact CG1-CE1 3.6Å; V137-F240 HydrophobicContact CG1-CE2 4.43Å; V137-F240 HydrophobicContact CG1-CZ 3.47Å; V137-F240 VanDerWaalsContact CG1-CZ 3.47Å; V137-V381 HydrophobicContact CB-CG1 4.39Å; V137-V381 HydrophobicContact CG1-CG1 3.84Å; V137-V381 HydrophobicContact CG2-CG1 4.12Å; V137-L384 HydrophobicContact CG2-CB 3.52Å; V137-L384 HydrophobicContact CG2-CD1 4.13Å; V137-L384 HydrophobicContact CG2-CG 4.49Å; V137-I385 HydrophobicContact CG1-CD1 4.35Å; V137-I385 HydrophobicContact CG1-CG1 4.14Å; V137-I385 HydrophobicContact CG2-CG1 4.08Å
138	I	93.9	Very high	93.3	Very high	14 Å²	14	12.5 Å²	12.5	7%	0.072	7%	0.065	C	C	.	.	H	α-helix	trans	-61.6	-42.9	177.7	-61.3	157.9	0	0	0	110.9	S56 S134 Q135 A136 T141 F142 C323 L327	S56-I138 VanDerWaalsContact OG-CG1 3.27Å; S56-I138 WeakPolarHBondContact OG-CG1 3.21Å; S134-I138 WeakPolarHBondContact O-CD1 3.03Å; S134-I138 VanDerWaalsContact O-CG1 3.24Å; S134-I138 WeakPolarHBondContact O-CG1 3.16Å; S134-I138 PolarHBondContact O-N 2.91Å; Q135-I138 PolarHBondContact O-N 3Å; A136-I138 PolarHBondContact O-N 3.24Å; I138-T141 WeakPolarHBondContact O-CB 3.35Å; I138-T141 PolarHBondContact O-N 3.14Å; I138-F142 PolarHBondContact O-N 3.44Å; I138-C323 HydrophobicContact CG2-CB 4.04Å; I138-C323 WeakPolarHBondContact CG2-O 3.24Å; I138-L327 HydrophobicContact CG2-CB 3.78Å
139	A	95.8	Very high	93	Very high	0 Å²	0	13.9 Å²	13.9	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-67.9	-38.5	-179.5	0	0	0	0	0	112.9	Q135 A136 V137 T141 F142 A143 A165 I169 L327	Q135-A139 VanDerWaalsContact O-CB 3.28Å; Q135-A139 WeakPolarHBondContact O-CB 3.33Å; Q135-A139 PolarHBondContact O-N 3.01Å; A136-A139 PolarHBondContact O-N 2.53Å; V137-A139 VanDerWaalsContact C-N 3.34Å; V137-A139 PolarHBondContact O-N 3.34Å; A139-T141 VanDerWaalsContact C-N 3.34Å; A139-F142 WeakPolarHBondContact O-CB 3.4Å; A139-F142 PolarHBondContact O-N 2.77Å; A139-A143 PolarHBondContact O-N 3.5Å; A139-A165 HydrophobicContact CB-CB 3.98Å; A139-A165 WeakPolarHBondContact O-CB 3.31Å; A139-I169 HydrophobicContact CB-CD1 3.43Å; A139-I169 VanDerWaalsContact CB-CD1 3.43Å; A139-I169 HydrophobicContact CB-CG1 3.7Å; A139-L327 HydrophobicContact CB-CD2 3.91Å
140	I	95.1	Very high	92.8	Very high	3 Å²	3	20.1 Å²	20.1	2%	0.015	11%	0.108	C	C	.	.	H	α-helix	trans	-65.7	-42.3	174.3	-63.6	155.6	0	0	0	109.8	A136 V137 F142 A143 N144 L376 V381 L384	A136-I140 VanDerWaalsContact O-CD1 3.29Å; A136-I140 WeakPolarHBondContact O-CD1 3.3Å; A136-I140 WeakPolarHBondContact O-CG1 3.25Å; A136-I140 PolarHBondContact O-N 3.44Å; V137-I140 PolarHBondContact O-N 3.46Å; I140-F142 PolarHBondContact O-N 3.07Å; I140-A143 PolarHBondContact O-N 3.39Å; I140-N144 WeakPolarHBondContact O-CB 3.4Å; I140-N144 PolarHBondContact O-N 3.38Å; I140-L376 HydrophobicContact CD1-CD2 4.02Å; I140-L376 HydrophobicContact CG1-CD2 3.67Å; I140-V381 HydrophobicContact CB-CG2 4.27Å; I140-V381 HydrophobicContact CD1-CG2 4.05Å; I140-V381 HydrophobicContact CG2-CG2 3.54Å; I140-L384 HydrophobicContact CD1-CD1 3.73Å
141	T	93.3	Very high	92.5	Very high	2 Å²	2	23 Å²	23	1%	0.012	12%	0.12	C	C	.	.	H	α-helix	trans	-58.8	-48.3	174.6	-47	0	0	0	0	110.8	F59 V60 V137 I138 A139 A143 N144 Y145	F59-T141 HydrophobicContact CB-CG2 4.39Å; V60-T141 HydrophobicContact CG2-CG2 3.5Å; V60-T141 WeakPolarHBondContact CG2-OG1 3.35Å; V137-T141 PolarHBondContact O-N 3.5Å; V137-T141 PolarHBondContact O-OG1 2.96Å; I138-T141 WeakPolarHBondContact O-CB 3.35Å; I138-T141 PolarHBondContact O-N 3.14Å; A139-T141 VanDerWaalsContact C-N 3.34Å; T141-A143 VanDerWaalsContact C-N 3.29Å; T141-A143 PolarHBondContact O-N 3.28Å; T141-N144 PolarHBondContact O-N 2.9Å; T141-Y145 HydrophobicContact CG2-CD2 3.74Å; T141-Y145 HydrophobicContact CG2-CE2 3.85Å; T141-Y145 WeakPolarHBondContact O-CB 3.39Å; T141-Y145 VanDerWaalsContact O-CD2 3.26Å; T141-Y145 WeakPolarHBondContact O-CD2 3.47Å; T141-Y145 PolarHBondContact O-N 2.75Å
142	F	93.7	Very high	91.7	Very high	27 Å²	27	26.1 Å²	26.1	12%	0.118	14%	0.143	C	C	.	.	H	α-helix	trans	-52.2	-49.2	175.1	167.1	-97.2	0	0	0	111.7	I138 A139 I140 L146 V164 C168 A320 C323 Y324	I138-F142 PolarHBondContact O-N 3.44Å; A139-F142 WeakPolarHBondContact O-CB 3.4Å; A139-F142 PolarHBondContact O-N 2.77Å; I140-F142 PolarHBondContact O-N 3.07Å; F142-L146 HydrophobicContact CE1-CD2 4.07Å; F142-L146 HydrophobicContact CZ-CD2 3.86Å; F142-L146 WeakPolarHBondContact O-CB 3.14Å; F142-L146 PolarHBondContact O-N 3.33Å; F142-V164 HydrophobicContact CD1-CG1 4.35Å; F142-V164 HydrophobicContact CE1-CG1 3.95Å; F142-C168 HydrophobicContact CD1-CB 3.76Å; F142-C168 HydrophobicContact CE1-CB 3.68Å; F142-A320 HydrophobicContact CD2-CB 3.97Å; F142-A320 VanDerWaalsContact CD2-O 3.28Å; F142-A320 WeakPolarHBondContact CD2-O 3.36Å; F142-A320 HydrophobicContact CE2-CB 4Å; F142-C323 HydrophobicContact CB-CB 3.66Å; F142-C323 HydrophobicContact CD2-CB 4.42Å; F142-Y324 HydrophobicContact CE2-CD2 4.42Å
143	A	94.8	Very high	91	Very high	0 Å²	0	32.7 Å²	32.7	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-66.8	-46.5	-177.7	0	0	0	0	0	112.4	A139 I140 T141 Y145 L146 V147 S161 V164 A165	A139-A143 PolarHBondContact O-N 3.5Å; I140-A143 PolarHBondContact O-N 3.39Å; T141-A143 VanDerWaalsContact C-N 3.29Å; T141-A143 PolarHBondContact O-N 3.28Å; A143-Y145 VanDerWaalsContact C-N 3.3Å; A143-Y145 PolarHBondContact O-N 2.9Å; A143-L146 PolarHBondContact O-N 3.14Å; A143-L146 VanDerWaalsContact O-N 3.15Å; A143-V147 WeakPolarHBondContact O-CB 3.28Å; A143-V147 WeakPolarHBondContact O-CG2 3.46Å; A143-V147 PolarHBondContact O-N 3.12Å; A143-S161 WeakPolarHBondContact CB-O 3.47Å; A143-V164 HydrophobicContact CB-CB 3.95Å; A143-V164 HydrophobicContact CB-CG1 3.82Å; A143-A165 HydrophobicContact CB-CB 3.97Å
144	N	92	Very high	90.5	Very high	20 Å²	20	36 Å²	36	11%	0.107	21%	0.206	C	C	.	.	H	α-helix	trans	-58.7	-44	178.7	-72.8	-4	0	0	0	111	I140 T141 L146 V147 Q148 S161	I140-N144 WeakPolarHBondContact O-CB 3.4Å; I140-N144 PolarHBondContact O-N 3.38Å; T141-N144 PolarHBondContact O-N 2.9Å; N144-L146 VanDerWaalsContact C-N 3.34Å; N144-L146 PolarHBondContact O-N 2.71Å; N144-V147 PolarHBondContact O-N 3Å; N144-Q148 WeakPolarHBondContact O-CB 3.13Å; N144-Q148 PolarHBondContact O-N 3.34Å; N144-S161 WeakPolarHBondContact OD1-CB 3.49Å; N144-S161 PolarHBondContact OD1-OG 3.35Å
145	Y	91.4	Very high	89.8	Confident	0 Å²	0	42.2 Å²	42.2	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-69.9	-28.1	178.9	-85.9	-96.1	0	0	0	114	F59 T141 A143 P149 A298 V299 A300 V301 P316 V319	F59-Y145 HydrophobicContact CB-CE1 4.5Å; F59-Y145 HydrophobicContact CB-CE2 3.87Å; F59-Y145 WeakPolarHBondContact CB-OH 3.5Å; F59-Y145 PolarHBondContact O-OH 3.07Å; T141-Y145 HydrophobicContact CG2-CD2 3.74Å; T141-Y145 HydrophobicContact CG2-CE2 3.85Å; T141-Y145 WeakPolarHBondContact O-CB 3.39Å; T141-Y145 VanDerWaalsContact O-CD2 3.26Å; T141-Y145 WeakPolarHBondContact O-CD2 3.47Å; T141-Y145 PolarHBondContact O-N 2.75Å; A143-Y145 VanDerWaalsContact C-N 3.3Å; A143-Y145 PolarHBondContact O-N 2.9Å; Y145-P149 WeakPolarHBondContact O-CD 3.33Å; Y145-A298 HydrophobicContact CD1-CB 4.18Å; Y145-A298 HydrophobicContact CD2-CB 3.95Å; Y145-A298 HydrophobicContact CE1-CB 3.99Å; Y145-A298 HydrophobicContact CE2-CB 3.76Å; Y145-A298 HydrophobicContact CG-CB 4.18Å; Y145-V299 PolarHBondContact OH-N 3.32Å; Y145-A300 HydrophobicContact CE1-CB 3.86Å; Y145-A300 PolarHBondContact OH-N 2.85Å; Y145-V301 HydrophobicContact CD1-CG2 3.56Å; Y145-V301 HydrophobicContact CE1-CG2 3.75Å; Y145-V301 HydrophobicContact CG-CG2 4.48Å; Y145-P316 WeakPolarHBondContact O-CB 3.39Å; Y145-V319 HydrophobicContact CD1-CB 3.49Å; Y145-V319 VanDerWaalsContact CD1-CB 3.49Å; Y145-V319 HydrophobicContact CD1-CG1 3.34Å; Y145-V319 HydrophobicContact CD1-CG2 3.96Å; Y145-V319 HydrophobicContact CD2-CG1 3.9Å; Y145-V319 HydrophobicContact CE1-CB 3.89Å; Y145-V319 HydrophobicContact CE1-CG1 3.6Å; Y145-V319 HydrophobicContact CE1-CG2 3.88Å; Y145-V319 HydrophobicContact CE2-CG1 4.13Å; Y145-V319 HydrophobicContact CG-CB 4.02Å; Y145-V319 HydrophobicContact CG-CG1 3.49Å; Y145-V319 VanDerWaalsContact CG-CG1 3.49Å
146	L	91.6	Very high	89.4	Confident	82 Å²	82	42.8 Å²	42.8	43%	0.429	24%	0.237	S	C	.	.	H	α-helix	trans	-80.1	-36	176.1	-173.4	63.3	0	0	0	112.4	F142 A143 N144 V164	F142-L146 HydrophobicContact CE1-CD2 4.07Å; F142-L146 HydrophobicContact CZ-CD2 3.86Å; F142-L146 WeakPolarHBondContact O-CB 3.14Å; F142-L146 PolarHBondContact O-N 3.33Å; A143-L146 PolarHBondContact O-N 3.14Å; A143-L146 VanDerWaalsContact O-N 3.15Å; N144-L146 VanDerWaalsContact C-N 3.34Å; N144-L146 PolarHBondContact O-N 2.71Å; L146-V164 HydrophobicContact CD2-CG1 4.09Å
147	V	91.3	Very high	89.1	Confident	10 Å²	10	45.9 Å²	45.9	6%	0.061	26%	0.257	C	S	.	.	H	α-helix	trans	-88.9	-34.9	-174.1	-178.2	0	0	0	0	111.7	A143 N144 P149 L150 F151 P156 V164	A143-V147 WeakPolarHBondContact O-CB 3.28Å; A143-V147 WeakPolarHBondContact O-CG2 3.46Å; A143-V147 PolarHBondContact O-N 3.12Å; N144-V147 PolarHBondContact O-N 3Å; V147-P149 VanDerWaalsContact C-CD 3.44Å; V147-L150 WeakPolarHBondContact O-CB 3.48Å; V147-L150 PolarHBondContact O-N 3.36Å; V147-F151 HydrophobicContact CG1-CD2 3.74Å; V147-F151 HydrophobicContact CG1-CE2 3.66Å; V147-P156 HydrophobicContact CB-CB 4.41Å; V147-P156 HydrophobicContact CG1-CB 3.58Å; V147-V164 HydrophobicContact CG2-CG2 4.16Å
148	Q	87.5	Confident	88.8	Confident	27 Å²	27	50.7 Å²	50.7	13%	0.126	28%	0.276	C	S	.	.	G	3₁₀ helix	trans	-50.4	-44.4	-178.2	-173.7	68	31.3	0	0	114	N144 L150 F151 A298 V301	N144-Q148 WeakPolarHBondContact O-CB 3.13Å; N144-Q148 PolarHBondContact O-N 3.34Å; Q148-L150 PolarHBondContact O-N 2.94Å; Q148-L150 VanDerWaalsContact O-N 3.14Å; Q148-F151 CarbonylContact O-C 3.23Å; Q148-F151 VanDerWaalsContact O-C 3.23Å; Q148-F151 PolarHBondContact O-N 3.35Å; Q148-A298 HydrophobicContact CB-CB 4.17Å; Q148-A298 HydrophobicContact CG-CB 4.16Å; Q148-V301 HydrophobicContact CG-CB 4.4Å; Q148-V301 HydrophobicContact CG-CG1 4.09Å
149	P	86.4	Confident	88.7	Confident	57 Å²	57	54.4 Å²	54.4	37%	0.37	30%	0.299	S	S	.	.	G	3₁₀ helix	trans	-63.9	-20.3	-179.9	-22.4	35.2	0	0	0	114.3	Y145 V147 F151 V301 P316	Y145-P149 WeakPolarHBondContact O-CD 3.33Å; V147-P149 VanDerWaalsContact C-CD 3.44Å; P149-F151 VanDerWaalsContact C-N 3.31Å; P149-V301 HydrophobicContact CG-CG1 4.39Å; P149-P316 HydrophobicContact CG-CB 3.51Å; P149-P316 HydrophobicContact CG-CG 3.64Å
150	L	88.1	Confident	88.4	Confident	132 Å²	132	56.1 Å²	56.1	69%	0.691	31%	0.314	S	S	*	.	G	3₁₀ helix	trans	-80.1	-17	175.7	-55.6	175.9	0	0	0	112.2	V147 Q148 P152	V147-L150 WeakPolarHBondContact O-CB 3.48Å; V147-L150 PolarHBondContact O-N 3.36Å; Q148-L150 PolarHBondContact O-N 2.94Å; Q148-L150 VanDerWaalsContact O-N 3.14Å; L150-P152 VanDerWaalsContact C-CD 3.42Å; L150-P152 WeakPolarHBondContact O-CD 3.25Å
151	F	86.8	Confident	88.3	Confident	64 Å²	64	56.2 Å²	56.2	28%	0.281	32%	0.315	S	S	.	.			trans	-125.6	65.5	179.6	-61.7	-91.1	0	0	0	109.9	V147 Q148 P149 T153 C154 P156 P157	V147-F151 HydrophobicContact CG1-CD2 3.74Å; V147-F151 HydrophobicContact CG1-CE2 3.66Å; Q148-F151 CarbonylContact O-C 3.23Å; Q148-F151 VanDerWaalsContact O-C 3.23Å; Q148-F151 PolarHBondContact O-N 3.35Å; P149-F151 VanDerWaalsContact C-N 3.31Å; F151-T153 VanDerWaalsContact C-N 3.27Å; F151-T153 PolarHBondContact O-N 3.05Å; F151-C154 WeakPolarHBondContact CB-O 3.4Å; F151-P156 HydrophobicContact CB-CB 4.41Å; F151-P156 HydrophobicContact CD2-CB 3.9Å; F151-P156 HydrophobicContact CE2-CB 4.49Å; F151-P156 HydrophobicContact CG-CB 4.25Å; F151-P157 HydrophobicContact CE1-CG 4.26Å; F151-P157 HydrophobicContact CZ-CG 4.19Å
152	P	76.2	Confident	88.3	Confident	95 Å²	95	57.3 Å²	57.3	62%	0.617	32%	0.318	S	S	*	.	S	Bend	trans	-69.3	-22.6	-174.2	27.4	-35.2	0	0	0	113.7	L150	L150-P152 VanDerWaalsContact C-CD 3.42Å; L150-P152 WeakPolarHBondContact O-CD 3.25Å
153	T	79.3	Confident	88.4	Confident	138 Å²	138	61.6 Å²	61.6	85%	0.847	34%	0.342	S	S	*	.	S	Bend	trans	-111.9	-3.7	-174.5	52.7	0	0	0	0	114.1	F151	F151-T153 VanDerWaalsContact C-N 3.27Å; F151-T153 PolarHBondContact O-N 3.05Å
154	C	83.3	Confident	88.4	Confident	71 Å²	71	63.7 Å²	63.7	48%	0.48	36%	0.355	S	S	.	.	S	Bend	trans	-146.1	163.8	-178.8	55.7	0	0	0	0	110.9	F151	F151-C154 WeakPolarHBondContact CB-O 3.4Å
155	E	80.2	Confident	88.6	Confident	144 Å²	144	62.8 Å²	62.8	67%	0.673	35%	0.35	S	S	*	.	P	Polyproline II helix	trans	-72.2	135	176.3	-69.5	-179.8	178.3	0	0	110.6
156	P	85.3	Confident	88.9	Confident	13 Å²	13	63.8 Å²	63.8	8%	0.084	36%	0.358	C	S	.	.	P	Polyproline II helix	trans	-64	141.3	177.5	27	-33.9	0	0	0	110.3	V147 F151 Y158	V147-P156 HydrophobicContact CB-CB 4.41Å; V147-P156 HydrophobicContact CG1-CB 3.58Å; F151-P156 HydrophobicContact CB-CB 4.41Å; F151-P156 HydrophobicContact CD2-CB 3.9Å; F151-P156 HydrophobicContact CE2-CB 4.49Å; F151-P156 HydrophobicContact CG-CB 4.25Å; P156-Y158 PolarHBondContact O-N 3.14Å
157	P	90	Very high	89.2	Confident	64 Å²	64	62.8 Å²	62.8	42%	0.416	36%	0.362	S	S	.	.	P	Polyproline II helix	trans	-59.1	127	179.9	-23.3	32.2	0	0	0	111.6	F151 T159 A160 S161	F151-P157 HydrophobicContact CE1-CG 4.26Å; F151-P157 HydrophobicContact CZ-CG 4.19Å; P157-T159 VanDerWaalsContact C-N 3.26Å; P157-T159 PolarHBondContact O-N 3.25Å; P157-T159 VanDerWaalsContact O-N 3.16Å; P157-A160 HydrophobicContact CB-CB 4.21Å; P157-A160 WeakPolarHBondContact O-CB 3.33Å; P157-A160 PolarHBondContact O-N 3.31Å; P157-S161 PolarHBondContact O-N 3.06Å
158	Y	89.2	Confident	89.4	Confident	101 Å²	101	62.6 Å²	62.6	40%	0.396	36%	0.361	S	S	.	.	H	α-helix	trans	-46.9	-48.7	179.8	174.1	-99.1	0	0	0	112.8	P156 A160 S161 R162 E379	P156-Y158 PolarHBondContact O-N 3.14Å; Y158-A160 VanDerWaalsContact C-N 3.28Å; Y158-A160 PolarHBondContact O-N 2.76Å; Y158-S161 PolarHBondContact O-N 3.11Å; Y158-R162 HydrophobicContact CD1-CG 4.18Å; Y158-R162 HydrophobicContact CD2-CG 4.22Å; Y158-R162 HydrophobicContact CE1-CG 3.76Å; Y158-R162 HydrophobicContact CE2-CG 3.81Å; Y158-R162 HydrophobicContact CG-CG 4.39Å; Y158-R162 WeakPolarHBondContact O-CG 3.4Å; Y158-R162 PolarHBondContact O-N 3.14Å; Y158-R162 PolarHBondContact OH-NE 3.37Å; Y158-E379 HydrophobicContact CE2-CB 4.37Å; Y158-E379 HydrophobicContact CE2-CG 4.43Å; Y158-E379 WeakPolarHBondContact OH-CA 3.29Å
159	T	90.7	Very high	89.8	Confident	92 Å²	92	61.3 Å²	61.3	56%	0.564	36%	0.355	S	S	*	.	H	α-helix	trans	-60.6	-36.1	-179.7	-48.2	0	0	0	0	112.6	P157 L163	P157-T159 VanDerWaalsContact C-N 3.26Å; P157-T159 PolarHBondContact O-N 3.25Å; P157-T159 VanDerWaalsContact O-N 3.16Å; T159-L163 HydrophobicContact CG2-CD1 4.02Å; T159-L163 HydrophobicContact CG2-CG 4.35Å; T159-L163 WeakPolarHBondContact O-CB 3.42Å; T159-L163 VanDerWaalsContact O-CG 3.25Å; T159-L163 WeakPolarHBondContact O-CG 3.33Å; T159-L163 PolarHBondContact O-N 3Å
160	A	91.1	Very high	90.2	Very high	36 Å²	36	61.3 Å²	61.3	30%	0.298	36%	0.356	S	S	.	.	H	α-helix	trans	-67	-49.2	179.1	0	0	0	0	0	110.8	P157 Y158 R162 L163 V164	P157-A160 HydrophobicContact CB-CB 4.21Å; P157-A160 WeakPolarHBondContact O-CB 3.33Å; P157-A160 PolarHBondContact O-N 3.31Å; Y158-A160 VanDerWaalsContact C-N 3.28Å; Y158-A160 PolarHBondContact O-N 2.76Å; A160-R162 VanDerWaalsContact C-N 3.32Å; A160-R162 PolarHBondContact O-N 3.02Å; A160-L163 PolarHBondContact O-N 3.46Å; A160-V164 VanDerWaalsContact O-CG2 3.3Å; A160-V164 WeakPolarHBondContact O-CG2 3.48Å; A160-V164 PolarHBondContact O-N 3.13Å
161	S	91.3	Very high	90.5	Very high	5 Å²	5	59.3 Å²	59.3	4%	0.035	35%	0.345	C	S	.	.	H	α-helix	trans	-59.5	-42.2	176.5	-61.8	0	0	0	0	111.7	A143 N144 P157 Y158 V164 A165	A143-S161 WeakPolarHBondContact CB-O 3.47Å; N144-S161 WeakPolarHBondContact OD1-CB 3.49Å; N144-S161 PolarHBondContact OD1-OG 3.35Å; P157-S161 PolarHBondContact O-N 3.06Å; Y158-S161 PolarHBondContact O-N 3.11Å; S161-V164 PolarHBondContact O-N 3.15Å; S161-A165 WeakPolarHBondContact O-CB 3.3Å; S161-A165 PolarHBondContact O-N 3.47Å
162	R	94	Very high	90.7	Very high	25 Å²	25	56.3 Å²	56.3	9%	0.094	33%	0.332	C	S	.	.	H	α-helix	trans	-67.2	-40.1	179	-65.2	-61.9	175.1	148.1	-6.6	113.5	Y158 A160 A165 A166 L376 V378 E379	Y158-R162 HydrophobicContact CD1-CG 4.18Å; Y158-R162 HydrophobicContact CD2-CG 4.22Å; Y158-R162 HydrophobicContact CE1-CG 3.76Å; Y158-R162 HydrophobicContact CE2-CG 3.81Å; Y158-R162 HydrophobicContact CG-CG 4.39Å; Y158-R162 WeakPolarHBondContact O-CG 3.4Å; Y158-R162 PolarHBondContact O-N 3.14Å; Y158-R162 PolarHBondContact OH-NE 3.37Å; A160-R162 VanDerWaalsContact C-N 3.32Å; A160-R162 PolarHBondContact O-N 3.02Å; R162-A165 PolarHBondContact O-N 3.25Å; R162-A166 WeakPolarHBondContact O-CB 3.39Å; R162-A166 PolarHBondContact O-N 2.98Å; R162-L376 PolarHBondContact NH1-O 3.34Å; R162-V378 PolarHBondContact NH1-O 2.76Å; R162-V378 PolarHBondContact NH2-O 3.49Å; R162-E379 PolarHBondContact NH2-O 3.47Å
163	L	95.6	Very high	91.4	Very high	118 Å²	118	52.2 Å²	52.2	62%	0.618	31%	0.305	S	S	*	.	H	α-helix	trans	-67.3	-38.4	175.7	-72.3	175	0	0	0	112	T159 A160 A166 A167	T159-L163 HydrophobicContact CG2-CD1 4.02Å; T159-L163 HydrophobicContact CG2-CG 4.35Å; T159-L163 WeakPolarHBondContact O-CB 3.42Å; T159-L163 VanDerWaalsContact O-CG 3.25Å; T159-L163 WeakPolarHBondContact O-CG 3.33Å; T159-L163 PolarHBondContact O-N 3Å; A160-L163 PolarHBondContact O-N 3.46Å; L163-A166 PolarHBondContact O-N 3.11Å; L163-A167 VanDerWaalsContact O-CB 3.31Å; L163-A167 WeakPolarHBondContact O-CB 3.13Å; L163-A167 PolarHBondContact O-N 2.85Å
164	V	95.9	Very high	92	Very high	44 Å²	44	52.5 Å²	52.5	27%	0.267	30%	0.295	S	S	.	.	H	α-helix	trans	-64.6	-42.8	174.3	171.2	0	0	0	0	111	F142 A143 L146 V147 A160 S161 A167 C168	F142-V164 HydrophobicContact CD1-CG1 4.35Å; F142-V164 HydrophobicContact CE1-CG1 3.95Å; A143-V164 HydrophobicContact CB-CB 3.95Å; A143-V164 HydrophobicContact CB-CG1 3.82Å; L146-V164 HydrophobicContact CD2-CG1 4.09Å; V147-V164 HydrophobicContact CG2-CG2 4.16Å; A160-V164 VanDerWaalsContact O-CG2 3.3Å; A160-V164 WeakPolarHBondContact O-CG2 3.48Å; A160-V164 PolarHBondContact O-N 3.13Å; S161-V164 PolarHBondContact O-N 3.15Å; V164-A167 PolarHBondContact O-N 3.37Å; V164-C168 WeakPolarHBondContact O-CB 3.35Å; V164-C168 PolarHBondContact O-N 3.15Å
165	A	96.4	Very high	92.3	Very high	0 Å²	0	51 Å²	51	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-60.9	-46.4	174.9	0	0	0	0	0	111.8	A139 A143 S161 R162 C168 I169 L376	A139-A165 HydrophobicContact CB-CB 3.98Å; A139-A165 WeakPolarHBondContact O-CB 3.31Å; A143-A165 HydrophobicContact CB-CB 3.97Å; S161-A165 WeakPolarHBondContact O-CB 3.3Å; S161-A165 PolarHBondContact O-N 3.47Å; R162-A165 PolarHBondContact O-N 3.25Å; A165-C168 WeakPolarHBondContact O-CB 3.49Å; A165-C168 PolarHBondContact O-N 3.4Å; A165-I169 PolarHBondContact O-N 2.88Å; A165-L376 HydrophobicContact CB-CD1 4.34Å; A165-L376 HydrophobicContact CB-CD2 4Å
166	A	97.2	Very high	92.6	Very high	22 Å²	22	44.2 Å²	44.2	18%	0.182	25%	0.25	C	S	.	.	H	α-helix	trans	-62.1	-44.4	177	0	0	0	0	0	111.9	R162 L163 C168 I169 C170 L373 L376	R162-A166 WeakPolarHBondContact O-CB 3.39Å; R162-A166 PolarHBondContact O-N 2.98Å; L163-A166 PolarHBondContact O-N 3.11Å; A166-C168 VanDerWaalsContact C-N 3.3Å; A166-C168 PolarHBondContact O-N 3.47Å; A166-I169 PolarHBondContact O-N 2.93Å; A166-C170 WeakPolarHBondContact O-CB 3.49Å; A166-C170 PolarHBondContact O-N 3.4Å; A166-C170 PolarHBondContact O-SG 3.34Å; A166-C170 VanDerWaalsContact O-SG 3.33Å; A166-L373 HydrophobicContact CB-CD2 3.7Å; A166-L376 HydrophobicContact CB-CD1 3.75Å
167	A	97.1	Very high	92.6	Very high	61 Å²	61	44.4 Å²	44.4	50%	0.504	25%	0.252	S	S	.	.	H	α-helix	trans	-60.1	-40.6	175.8	0	0	0	0	0	111.7	L163 V164 C170 L171	L163-A167 VanDerWaalsContact O-CB 3.31Å; L163-A167 WeakPolarHBondContact O-CB 3.13Å; L163-A167 PolarHBondContact O-N 2.85Å; V164-A167 PolarHBondContact O-N 3.37Å; A167-C170 PolarHBondContact O-N 2.97Å; A167-L171 WeakPolarHBondContact O-CB 3.08Å; A167-L171 PolarHBondContact O-N 2.79Å
168	C	95.2	Very high	92.3	Very high	6 Å²	6	42.4 Å²	42.4	4%	0.041	24%	0.241	C	C	.	.	H	α-helix	trans	-62.9	-47.7	176.8	-170.5	0	0	0	0	112.2	F142 V164 A165 A166 L171 L172	F142-C168 HydrophobicContact CD1-CB 3.76Å; F142-C168 HydrophobicContact CE1-CB 3.68Å; V164-C168 WeakPolarHBondContact O-CB 3.35Å; V164-C168 PolarHBondContact O-N 3.15Å; A165-C168 WeakPolarHBondContact O-CB 3.49Å; A165-C168 PolarHBondContact O-N 3.4Å; A166-C168 VanDerWaalsContact C-N 3.3Å; A166-C168 PolarHBondContact O-N 3.47Å; C168-L171 PolarHBondContact O-N 2.92Å; C168-L172 WeakPolarHBondContact O-CB 3.28Å; C168-L172 PolarHBondContact O-N 3.47Å
169	I	95.8	Very high	91.7	Very high	0 Å²	0	42.9 Å²	42.9	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-60.7	-47.2	176.6	-72.1	163.1	0	0	0	111	A139 A165 A166 L171 L172 T173 L327 C369 L376	A139-I169 HydrophobicContact CB-CD1 3.43Å; A139-I169 VanDerWaalsContact CB-CD1 3.43Å; A139-I169 HydrophobicContact CB-CG1 3.7Å; A165-I169 PolarHBondContact O-N 2.88Å; A166-I169 PolarHBondContact O-N 2.93Å; I169-L171 PolarHBondContact O-N 2.74Å; I169-L172 PolarHBondContact O-N 2.81Å; I169-T173 VanDerWaalsContact O-CB 3.29Å; I169-T173 WeakPolarHBondContact O-CB 3.37Å; I169-T173 PolarHBondContact O-N 3.19Å; I169-T173 PolarHBondContact O-OG1 3.16Å; I169-L327 HydrophobicContact CG1-CD1 4.33Å; I169-L327 HydrophobicContact CG1-CD2 3.86Å; I169-C369 HydrophobicContact CG2-CB 4.48Å; I169-L376 HydrophobicContact CD1-CD1 3.87Å; I169-L376 HydrophobicContact CD1-CD2 4.31Å; I169-L376 HydrophobicContact CD1-CG 4.21Å
170	C	96.3	Very high	90.5	Very high	57 Å²	57	40.8 Å²	40.8	39%	0.385	23%	0.23	S	C	.	.	H	α-helix	trans	-62.1	-43.8	178.6	-72.6	0	0	0	0	111.9	A166 A167 T173 F174	A166-C170 WeakPolarHBondContact O-CB 3.49Å; A166-C170 PolarHBondContact O-N 3.4Å; A166-C170 PolarHBondContact O-SG 3.34Å; A166-C170 VanDerWaalsContact O-SG 3.33Å; A167-C170 PolarHBondContact O-N 2.97Å; C170-T173 PolarHBondContact O-N 3.11Å; C170-F174 WeakPolarHBondContact O-CB 3.46Å; C170-F174 PolarHBondContact O-N 2.82Å
171	L	93.3	Very high	89.3	Confident	90 Å²	90	45.3 Å²	45.3	47%	0.471	24%	0.243	S	C	.	.	H	α-helix	trans	-62.9	-48.1	178.6	178.5	62.9	0	0	0	111.4	A167 C168 I169 T173 F174 I175	A167-L171 WeakPolarHBondContact O-CB 3.08Å; A167-L171 PolarHBondContact O-N 2.79Å; C168-L171 PolarHBondContact O-N 2.92Å; I169-L171 PolarHBondContact O-N 2.74Å; L171-T173 VanDerWaalsContact C-N 3.35Å; L171-T173 PolarHBondContact O-N 2.99Å; L171-F174 WeakPolarHBondContact O-CB 3.15Å; L171-F174 PolarHBondContact O-N 2.79Å; L171-I175 HydrophobicContact CD1-CD1 4.11Å; L171-I175 HydrophobicContact CD1-CG1 4.44Å; L171-I175 HydrophobicContact CG-CD1 3.96Å; L171-I175 VanDerWaalsContact O-CG1 3.31Å; L171-I175 WeakPolarHBondContact O-CG1 3.5Å; L171-I175 PolarHBondContact O-N 2.84Å
172	L	91.4	Very high	88	Confident	1 Å²	1	53.6 Å²	53.6	1%	0.005	27%	0.273	C	S	.	.	H	α-helix	trans	-65.1	-39.5	178	-79.1	174.7	0	0	0	112.1	C168 I169 F174 I175 N176 Y324 L327 N328 I331	C168-L172 WeakPolarHBondContact O-CB 3.28Å; C168-L172 PolarHBondContact O-N 3.47Å; I169-L172 PolarHBondContact O-N 2.81Å; L172-F174 VanDerWaalsContact C-N 3.31Å; L172-F174 PolarHBondContact O-N 3.04Å; L172-I175 PolarHBondContact O-N 3.18Å; L172-N176 WeakPolarHBondContact O-CB 3.48Å; L172-N176 PolarHBondContact O-N 2.73Å; L172-N176 PolarHBondContact O-ND2 2.77Å; L172-Y324 HydrophobicContact CD1-CD2 4.16Å; L172-Y324 HydrophobicContact CD1-CE2 4.14Å; L172-Y324 HydrophobicContact CD2-CD1 4.29Å; L172-Y324 HydrophobicContact CD2-CD2 4.37Å; L172-Y324 HydrophobicContact CD2-CE1 3.61Å; L172-Y324 HydrophobicContact CD2-CE2 3.7Å; L172-Y324 WeakPolarHBondContact CD2-OH 3.3Å; L172-Y324 HydrophobicContact CG-CD2 4.34Å; L172-Y324 HydrophobicContact CG-CE2 3.81Å; L172-L327 HydrophobicContact CD1-CB 3.82Å; L172-L327 HydrophobicContact CD1-CD2 3.62Å; L172-L327 HydrophobicContact CD1-CG 3.58Å; L172-N328 HydrophobicContact CD1-CB 4.32Å; L172-N328 HydrophobicContact CD2-CB 3.86Å; L172-I331 HydrophobicContact CB-CD1 3.8Å; L172-I331 HydrophobicContact CD1-CD1 4.45Å
173	T	92	Very high	86.2	Confident	8 Å²	8	52.6 Å²	52.6	5%	0.049	27%	0.27	C	S	.	.	H	α-helix	trans	-61.1	-43	174.2	-58.6	0	0	0	0	110.8	I169 C170 L171 S177 L365 C369	I169-T173 VanDerWaalsContact O-CB 3.29Å; I169-T173 WeakPolarHBondContact O-CB 3.37Å; I169-T173 PolarHBondContact O-N 3.19Å; I169-T173 PolarHBondContact O-OG1 3.16Å; C170-T173 PolarHBondContact O-N 3.11Å; L171-T173 VanDerWaalsContact C-N 3.35Å; L171-T173 PolarHBondContact O-N 2.99Å; T173-S177 VanDerWaalsContact O-CB 3.28Å; T173-S177 WeakPolarHBondContact O-CB 3.39Å; T173-S177 PolarHBondContact O-N 3.21Å; T173-S177 PolarHBondContact O-OG 2.85Å; T173-L365 HydrophobicContact CG2-CB 4.12Å; T173-C369 HydrophobicContact CG2-CB 3.7Å; T173-C369 WeakPolarHBondContact OG1-CB 3.42Å
174	F	91.6	Very high	84.4	Confident	144 Å²	144	49.9 Å²	49.9	63%	0.632	26%	0.259	S	S	*	.	H	α-helix	trans	-62.3	-47.9	175.8	175	-99.2	0	0	0	112	C170 L171 L172 N176 S177 A178	C170-F174 WeakPolarHBondContact O-CB 3.46Å; C170-F174 PolarHBondContact O-N 2.82Å; L171-F174 WeakPolarHBondContact O-CB 3.15Å; L171-F174 PolarHBondContact O-N 2.79Å; L172-F174 VanDerWaalsContact C-N 3.31Å; L172-F174 PolarHBondContact O-N 3.04Å; F174-N176 PolarHBondContact O-N 3.16Å; F174-S177 PolarHBondContact O-N 2.81Å; F174-A178 VanDerWaalsContact O-CB 3.28Å; F174-A178 WeakPolarHBondContact O-CB 3.41Å; F174-A178 PolarHBondContact O-N 3.23Å
175	I	88.2	Confident	82.8	Confident	39 Å²	39	57 Å²	57	20%	0.2	28%	0.281	C	S	.	.	H	α-helix	trans	-59.4	-47.4	178.3	-68.8	166.1	0	0	0	110.7	L171 L172 S177 A178 Y179 W182 Y324	L171-I175 HydrophobicContact CD1-CD1 4.11Å; L171-I175 HydrophobicContact CD1-CG1 4.44Å; L171-I175 HydrophobicContact CG-CD1 3.96Å; L171-I175 VanDerWaalsContact O-CG1 3.31Å; L171-I175 WeakPolarHBondContact O-CG1 3.5Å; L171-I175 PolarHBondContact O-N 2.84Å; L172-I175 PolarHBondContact O-N 3.18Å; I175-S177 VanDerWaalsContact C-N 3.32Å; I175-S177 PolarHBondContact O-N 2.8Å; I175-A178 PolarHBondContact O-N 3.47Å; I175-A178 VanDerWaalsContact O-N 3.15Å; I175-Y179 PolarHBondContact O-N 2.79Å; I175-W182 HydrophobicContact CG2-CB 4.47Å; I175-Y324 WeakPolarHBondContact CD1-OH 3.39Å
176	N	86.4	Confident	81.1	Confident	3 Å²	3	59.6 Å²	59.6	2%	0.016	30%	0.297	C	S	.	.	H	α-helix	trans	-68.1	-31.3	179.5	-76.3	-62.4	0	0	0	113	L172 F174 A178 N328 I332 L365	L172-N176 WeakPolarHBondContact O-CB 3.48Å; L172-N176 PolarHBondContact O-N 2.73Å; L172-N176 PolarHBondContact O-ND2 2.77Å; F174-N176 PolarHBondContact O-N 3.16Å; N176-A178 VanDerWaalsContact C-N 3.34Å; N176-N328 PolarHBondContact ND2-OD1 3.11Å; N176-N328 PolarHBondContact OD1-OD1 2.78Å; N176-I332 WeakPolarHBondContact OD1-CD1 3.48Å; N176-I332 WeakPolarHBondContact OD1-CG1 3.44Å; N176-L365 HydrophobicContact CB-CD1 4.09Å; N176-L365 HydrophobicContact CB-CD2 4.24Å
177	S	85.7	Confident	79.3	Confident	16 Å²	16	60.4 Å²	60.4	11%	0.112	30%	0.297	C	S	.	.	H	α-helix	trans	-70.1	-35	172.5	-60.2	0	0	0	0	111.3	T173 F174 I175 T360	T173-S177 VanDerWaalsContact O-CB 3.28Å; T173-S177 WeakPolarHBondContact O-CB 3.39Å; T173-S177 PolarHBondContact O-N 3.21Å; T173-S177 PolarHBondContact O-OG 2.85Å; F174-S177 PolarHBondContact O-N 2.81Å; I175-S177 VanDerWaalsContact C-N 3.32Å; I175-S177 PolarHBondContact O-N 2.8Å; S177-T360 PolarHBondContact O-OG1 2.92Å
178	A	84.1	Confident	77.6	Confident	23 Å²	23	62.6 Å²	62.6	19%	0.19	30%	0.3	C	S	.	.	H	α-helix	trans	-78.5	-51.8	-174.5	0	0	0	0	0	113.5	F174 I175 N176 R358	F174-A178 VanDerWaalsContact O-CB 3.28Å; F174-A178 WeakPolarHBondContact O-CB 3.41Å; F174-A178 PolarHBondContact O-N 3.23Å; I175-A178 PolarHBondContact O-N 3.47Å; I175-A178 VanDerWaalsContact O-N 3.15Å; N176-A178 VanDerWaalsContact C-N 3.34Å; A178-R358 WeakPolarHBondContact O-CD 3.21Å; A178-R358 PolarHBondContact O-NH1 3.38Å
179	Y	76.4	Confident	76.3	Confident	110 Å²	110	68 Å²	68	43%	0.431	33%	0.327	S	S	.	.			trans	-160.9	104.6	179.7	-162.2	-102.3	0	0	0	112.8	I175 K181 W182	I175-Y179 PolarHBondContact O-N 2.79Å; Y179-K181 VanDerWaalsContact C-N 3.29Å; Y179-K181 HydrophobicContact CD1-CB 3.96Å; Y179-K181 HydrophobicContact CE1-CB 3.55Å; Y179-K181 HydrophobicContact CE1-CD 4.02Å; Y179-K181 HydrophobicContact CE1-CG 3.97Å; Y179-K181 PolarHBondContact O-N 3.01Å; Y179-K181 VanDerWaalsContact O-N 3.15Å; Y179-W182 AromaticContact CD1-CD1 3.27Å; Y179-W182 HydrophobicContact CD1-CG 4.06Å; Y179-W182 AromaticContact CD1-NE1 3.66Å; Y179-W182 AromaticContact CE1-CD1 3.79Å; Y179-W182 PolarHBondContact O-N 2.82Å; Y179-W182 VanDerWaalsContact O-N 3.16Å
180	V	65.3	Low	75.1	Confident	48 Å²	48	69.6 Å²	69.6	29%	0.291	33%	0.334	S	S	.	.	H	α-helix	trans	-57.7	-34.4	-173	-173.2	0	0	0	0	113.8	W182 G183 T184 T360	V180-W182 PolarHBondContact O-N 2.8Å; V180-G183 PolarHBondContact O-N 3.3Å; V180-G183 VanDerWaalsContact O-N 3.09Å; V180-T184 PolarHBondContact O-N 3.44Å; V180-T360 HydrophobicContact CG2-CG2 3.36Å
181	K	66.6	Low	73.9	Confident	132 Å²	132	67.9 Å²	67.9	57%	0.574	32%	0.322	S	S	*	.	H	α-helix	trans	-69.7	-15.1	-175.8	-53.6	-177.8	179.5	174.8	0	113.6	Y179 T184	Y179-K181 VanDerWaalsContact C-N 3.29Å; Y179-K181 HydrophobicContact CD1-CB 3.96Å; Y179-K181 HydrophobicContact CE1-CB 3.55Å; Y179-K181 HydrophobicContact CE1-CD 4.02Å; Y179-K181 HydrophobicContact CE1-CG 3.97Å; Y179-K181 PolarHBondContact O-N 3.01Å; Y179-K181 VanDerWaalsContact O-N 3.15Å; K181-T184 PolarHBondContact O-OG1 3.28Å
182	W	63.1	Low	73	Confident	179 Å²	179	71.5 Å²	71.5	68%	0.678	33%	0.331	S	S	*	.	H	α-helix	trans	-74.9	-37.6	172.2	-75.3	25.2	0	0	0	110.7	I175 Y179 V180 T184 V186	I175-W182 HydrophobicContact CG2-CB 4.47Å; Y179-W182 AromaticContact CD1-CD1 3.27Å; Y179-W182 HydrophobicContact CD1-CG 4.06Å; Y179-W182 AromaticContact CD1-NE1 3.66Å; Y179-W182 AromaticContact CE1-CD1 3.79Å; Y179-W182 PolarHBondContact O-N 2.82Å; Y179-W182 VanDerWaalsContact O-N 3.16Å; V180-W182 PolarHBondContact O-N 2.8Å; W182-T184 PolarHBondContact O-N 3.2Å; W182-V186 VanDerWaalsContact O-CG2 3.29Å; W182-V186 WeakPolarHBondContact O-CG2 3.39Å
183	G	56.6	Low	72.3	Confident	3 Å²	3	73.2 Å²	73.2	3%	0.031	35%	0.345	C	S	.	.	H	α-helix	trans	-62.7	-40.1	176.8	0	0	0	0	0	112.9	V180 Q187 N328	V180-G183 PolarHBondContact O-N 3.3Å; V180-G183 VanDerWaalsContact O-N 3.09Å; G183-Q187 PolarHBondContact O-N 2.65Å; G183-N328 PolarHBondContact O-ND2 2.99Å; G183-N328 VanDerWaalsContact O-ND2 3.15Å
184	T	58.4	Low	71.6	Confident	62 Å²	62	73.3 Å²	73.3	38%	0.38	35%	0.345	S	S	.	.	H	α-helix	trans	-73.2	-38	-176.3	55.4	0	0	0	0	113.8	V180 K181 W182 V186 Q187	V180-T184 PolarHBondContact O-N 3.44Å; K181-T184 PolarHBondContact O-OG1 3.28Å; W182-T184 PolarHBondContact O-N 3.2Å; T184-V186 VanDerWaalsContact C-N 3.32Å; T184-V186 PolarHBondContact O-N 2.87Å; T184-Q187 PolarHBondContact O-N 3.48Å
185	R	62.3	Low	71.1	Confident	192 Å²	192	68.4 Å²	68.4	73%	0.725	33%	0.326	S	S	*	.	H	α-helix	trans	-68.1	-31.7	178.4	-74.6	-176.2	177	165.3	-1.3	113.4
186	V	61.1	Low	71	Confident	55 Å²	55	69 Å²	69	33%	0.333	34%	0.337	S	S	.	.	H	α-helix	trans	-73.2	-31.3	-179.4	170.6	0	0	0	0	111	W182 T184 F190 Y324	W182-V186 VanDerWaalsContact O-CG2 3.29Å; W182-V186 WeakPolarHBondContact O-CG2 3.39Å; T184-V186 VanDerWaalsContact C-N 3.32Å; T184-V186 PolarHBondContact O-N 2.87Å; V186-F190 HydrophobicContact CB-CE2 4.45Å; V186-F190 HydrophobicContact CG1-CD2 3.86Å; V186-F190 HydrophobicContact CG1-CE2 3.09Å; V186-F190 HydrophobicContact CG1-CZ 3.56Å; V186-F190 WeakPolarHBondContact O-CD2 3.29Å; V186-F190 WeakPolarHBondContact O-CG 3.35Å; V186-Y324 HydrophobicContact CG1-CE1 4.16Å
187	Q	59	Low	70.9	Confident	39 Å²	39	69 Å²	69	18%	0.182	34%	0.338	C	S	.	.	H	α-helix	trans	-69.1	-39.8	-178.7	-176.8	177.3	-18.3	0	0	114.1	G183 T184 I189 F190 T191	G183-Q187 PolarHBondContact O-N 2.65Å; T184-Q187 PolarHBondContact O-N 3.48Å; Q187-I189 VanDerWaalsContact C-N 3.34Å; Q187-I189 PolarHBondContact O-N 3.14Å; Q187-F190 PolarHBondContact O-N 3.36Å; Q187-T191 PolarHBondContact O-N 3.37Å; Q187-T191 PolarHBondContact O-OG1 3.27Å; Q187-T191 VanDerWaalsContact O-OG1 3.08Å
188	D	62	Low	71.1	Confident	107 Å²	107	68.4 Å²	68.4	57%	0.572	33%	0.333	S	S	*	.	H	α-helix	trans	-63.5	-40.2	-176.3	-73	-16.7	0	0	0	111.9	F190 T191 Y192	D188-F190 PolarHBondContact O-N 2.99Å; D188-T191 PolarHBondContact O-N 2.98Å; D188-Y192 VanDerWaalsContact O-CD2 3.23Å; D188-Y192 WeakPolarHBondContact O-CD2 3.4Å
189	I	67.6	Low	71.5	Confident	119 Å²	119	71.3 Å²	71.3	61%	0.61	35%	0.345	S	S	*	.	H	α-helix	trans	-65.3	-40.3	178.8	-63.3	172.7	0	0	0	110.8	Q187 T191 Y192 A193	Q187-I189 VanDerWaalsContact C-N 3.34Å; Q187-I189 PolarHBondContact O-N 3.14Å; I189-T191 VanDerWaalsContact C-N 3.28Å; I189-T191 PolarHBondContact O-N 2.98Å; I189-Y192 PolarHBondContact O-N 2.91Å; I189-A193 PolarHBondContact O-N 2.91Å
190	F	70.9	Confident	72.2	Confident	34 Å²	34	68.8 Å²	68.8	15%	0.149	34%	0.341	C	S	.	.	H	α-helix	trans	-73	-21.5	-177.7	-60.6	-25.2	0	0	0	113.6	V186 Q187 D188 A193 K194 L321 Y324	V186-F190 HydrophobicContact CB-CE2 4.45Å; V186-F190 HydrophobicContact CG1-CD2 3.86Å; V186-F190 HydrophobicContact CG1-CE2 3.09Å; V186-F190 HydrophobicContact CG1-CZ 3.56Å; V186-F190 WeakPolarHBondContact O-CD2 3.29Å; V186-F190 WeakPolarHBondContact O-CG 3.35Å; Q187-F190 PolarHBondContact O-N 3.36Å; D188-F190 PolarHBondContact O-N 2.99Å; F190-A193 PolarHBondContact O-N 3.11Å; F190-K194 PolarHBondContact O-N 3.43Å; F190-K194 VanDerWaalsContact O-N 3.16Å; F190-L321 HydrophobicContact CD1-CB 4.02Å; F190-L321 HydrophobicContact CD1-CD1 4.31Å; F190-L321 HydrophobicContact CD1-CD2 4.41Å; F190-L321 HydrophobicContact CD1-CG 4.48Å; F190-L321 HydrophobicContact CE1-CB 4.25Å; F190-L321 HydrophobicContact CE1-CD1 4.09Å; F190-L321 HydrophobicContact CE1-CD2 3.78Å; F190-L321 HydrophobicContact CE1-CG 4.26Å; F190-L321 HydrophobicContact CE2-CD2 4.29Å; F190-L321 HydrophobicContact CG-CB 4.23Å; F190-L321 HydrophobicContact CZ-CD2 3.72Å; F190-Y324 HydrophobicContact CD2-CD1 4.44Å; F190-Y324 AromaticContact CE2-CD1 3.84Å; F190-Y324 HydrophobicContact CE2-CD1 3.84Å; F190-Y324 HydrophobicContact CE2-CE1 4.37Å
191	T	70.1	Confident	73.5	Confident	21 Å²	21	66.5 Å²	66.5	13%	0.129	33%	0.327	C	S	.	.	H	α-helix	trans	-67	-38.6	176.9	-59.1	0	0	0	0	112.1	Q187 D188 I189 K194 V195	Q187-T191 PolarHBondContact O-N 3.37Å; Q187-T191 PolarHBondContact O-OG1 3.27Å; Q187-T191 VanDerWaalsContact O-OG1 3.08Å; D188-T191 PolarHBondContact O-N 2.98Å; I189-T191 VanDerWaalsContact C-N 3.28Å; I189-T191 PolarHBondContact O-N 2.98Å; T191-K194 VanDerWaalsContact O-CG 3.3Å; T191-K194 WeakPolarHBondContact O-CG 3.19Å; T191-V195 WeakPolarHBondContact O-CG2 3.45Å
192	Y	75	Confident	74.9	Confident	167 Å²	167	61.1 Å²	61.1	66%	0.655	30%	0.304	S	S	*	.	H	α-helix	trans	-72.5	-39.6	175.3	-63.2	-75	0	0	0	112	D188 I189 K194 V195 A196	D188-Y192 VanDerWaalsContact O-CD2 3.23Å; D188-Y192 WeakPolarHBondContact O-CD2 3.4Å; I189-Y192 PolarHBondContact O-N 2.91Å; Y192-K194 PolarHBondContact O-N 2.91Å; Y192-V195 PolarHBondContact O-N 3.18Å; Y192-A196 PolarHBondContact O-N 2.84Å; Y192-A196 VanDerWaalsContact O-N 3.08Å
193	A	75.9	Confident	76.4	Confident	36 Å²	36	57.3 Å²	57.3	30%	0.298	30%	0.296	S	S	.	.	H	α-helix	trans	-60.9	-41.5	-178.5	0	0	0	0	0	112.8	I189 F190 A196 A197	I189-A193 PolarHBondContact O-N 2.91Å; F190-A193 PolarHBondContact O-N 3.11Å; A193-A196 PolarHBondContact O-N 2.86Å; A193-A197 PolarHBondContact O-N 3.27Å
194	K	77.3	Confident	78.1	Confident	11 Å²	11	58.4 Å²	58.4	5%	0.048	30%	0.302	C	S	.	.	H	α-helix	trans	-71	-36.1	179.8	69.4	-174.5	177.9	-171.2	0	113.7	G51 I54 F190 T191 Y192 A196 A197 L198 S322	G51-K194 WeakPolarHBondContact O-CE 3.42Å; G51-K194 PolarHBondContact O-NZ 2.92Å; I54-K194 HydrophobicContact CG2-CD 4.35Å; I54-K194 HydrophobicContact CG2-CG 4.41Å; I54-K194 WeakPolarHBondContact O-CD 3.36Å; I54-K194 WeakPolarHBondContact O-CE 3.48Å; I54-K194 PolarHBondContact O-NZ 2.8Å; F190-K194 PolarHBondContact O-N 3.43Å; F190-K194 VanDerWaalsContact O-N 3.16Å; T191-K194 VanDerWaalsContact O-CG 3.3Å; T191-K194 WeakPolarHBondContact O-CG 3.19Å; Y192-K194 PolarHBondContact O-N 2.91Å; K194-A196 VanDerWaalsContact C-N 3.32Å; K194-A197 PolarHBondContact O-N 3.35Å; K194-L198 PolarHBondContact O-N 2.95Å; K194-L198 VanDerWaalsContact O-N 3.09Å; K194-S322 WeakPolarHBondContact CD-OG 3.43Å
195	V	81.5	Confident	79.8	Confident	40 Å²	40	55.5 Å²	55.5	24%	0.242	28%	0.284	C	S	.	.	H	α-helix	trans	-65.7	-41.1	175.5	175.5	0	0	0	0	109.5	I54 T191 Y192 A197 L198 I199	I54-V195 HydrophobicContact CD1-CG2 4.42Å; T191-V195 WeakPolarHBondContact O-CG2 3.45Å; Y192-V195 PolarHBondContact O-N 3.18Å; V195-A197 VanDerWaalsContact C-N 3.35Å; V195-A197 PolarHBondContact O-N 2.88Å; V195-L198 PolarHBondContact O-N 2.9Å; V195-I199 HydrophobicContact CG1-CD1 3.92Å; V195-I199 HydrophobicContact CG1-CG1 4.48Å; V195-I199 VanDerWaalsContact O-CG1 3.29Å; V195-I199 WeakPolarHBondContact O-CG1 3.34Å; V195-I199 PolarHBondContact O-N 2.84Å
196	A	85.1	Confident	81.4	Confident	51 Å²	51	50.3 Å²	50.3	42%	0.421	27%	0.27	S	S	.	.	H	α-helix	trans	-59.9	-42.8	173.6	0	0	0	0	0	112.3	Y192 A193 K194 L198 I199 V200	Y192-A196 PolarHBondContact O-N 2.84Å; Y192-A196 VanDerWaalsContact O-N 3.08Å; A193-A196 PolarHBondContact O-N 2.86Å; K194-A196 VanDerWaalsContact C-N 3.32Å; A196-L198 PolarHBondContact O-N 3.41Å; A196-I199 PolarHBondContact O-N 3.18Å; A196-V200 WeakPolarHBondContact O-CG2 3.2Å; A196-V200 PolarHBondContact O-N 3.42Å
197	A	85.8	Confident	82.9	Confident	5 Å²	5	51 Å²	51	4%	0.041	28%	0.275	C	S	.	.	H	α-helix	trans	-61.3	-41.9	177.1	0	0	0	0	0	112.8	A193 K194 V195 V200 I201 I315 A318	A193-A197 PolarHBondContact O-N 3.27Å; K194-A197 PolarHBondContact O-N 3.35Å; V195-A197 VanDerWaalsContact C-N 3.35Å; V195-A197 PolarHBondContact O-N 2.88Å; A197-V200 PolarHBondContact O-N 3.28Å; A197-I201 WeakPolarHBondContact O-CG1 3.36Å; A197-I201 PolarHBondContact O-N 3.47Å; A197-I201 VanDerWaalsContact O-N 3.12Å; A197-I315 HydrophobicContact CB-CD1 4.42Å; A197-A318 HydrophobicContact CB-CB 3.64Å
198	L	90.1	Very high	84.6	Confident	2 Å²	2	51.2 Å²	51.2	1%	0.01	28%	0.275	C	S	.	.	H	α-helix	trans	-66.5	-38.9	175	-70.3	176.7	0	0	0	112.3	I54 I58 F59 K194 V195 A196 V200 I201 I202 I276 T280	I54-L198 HydrophobicContact CD1-CD1 4.49Å; I54-L198 HydrophobicContact CG2-CD1 3.35Å; I58-L198 HydrophobicContact CG1-CD2 4.49Å; I58-L198 HydrophobicContact CG2-CD1 4.41Å; I58-L198 HydrophobicContact CG2-CD2 4.18Å; F59-L198 HydrophobicContact CE1-CD2 3.75Å; F59-L198 HydrophobicContact CZ-CD2 3.71Å; F59-L198 HydrophobicContact CZ-CG 4.17Å; K194-L198 PolarHBondContact O-N 2.95Å; K194-L198 VanDerWaalsContact O-N 3.09Å; V195-L198 PolarHBondContact O-N 2.9Å; A196-L198 PolarHBondContact O-N 3.41Å; L198-V200 VanDerWaalsContact C-N 3.31Å; L198-V200 PolarHBondContact O-N 3.25Å; L198-I201 HydrophobicContact CD2-CD1 4.46Å; L198-I201 PolarHBondContact O-N 2.85Å; L198-I202 VanDerWaalsContact O-CG1 3.26Å; L198-I202 WeakPolarHBondContact O-CG1 3.41Å; L198-I202 PolarHBondContact O-N 3.29Å; L198-I276 HydrophobicContact CB-CG2 4.32Å; L198-I276 HydrophobicContact CD1-CG2 3.8Å; L198-T280 HydrophobicContact CD2-CG2 4.06Å
199	I	91.2	Very high	86	Confident	85 Å²	85	48.3 Å²	48.3	44%	0.436	26%	0.259	S	S	.	.	H	α-helix	trans	-60.5	-42.8	175	-70.4	166.9	0	0	0	110.5	V195 A196 I201 I202 I203	V195-I199 HydrophobicContact CG1-CD1 3.92Å; V195-I199 HydrophobicContact CG1-CG1 4.48Å; V195-I199 VanDerWaalsContact O-CG1 3.29Å; V195-I199 WeakPolarHBondContact O-CG1 3.34Å; V195-I199 PolarHBondContact O-N 2.84Å; A196-I199 PolarHBondContact O-N 3.18Å; I199-I201 PolarHBondContact O-N 3.16Å; I199-I202 PolarHBondContact O-N 2.96Å; I199-I203 HydrophobicContact CG2-CD1 3.54Å; I199-I203 HydrophobicContact CG2-CG1 4.19Å; I199-I203 WeakPolarHBondContact O-CB 3.43Å; I199-I203 VanDerWaalsContact O-CG1 3.29Å; I199-I203 WeakPolarHBondContact O-CG1 3.48Å; I199-I203 PolarHBondContact O-N 2.96Å
200	V	91.4	Very high	87.2	Confident	57 Å²	57	47.9 Å²	47.9	35%	0.345	27%	0.265	S	S	.	.	H	α-helix	trans	-58.4	-49.3	175.4	171.4	0	0	0	0	110.6	A196 A197 L198 I202 I203 T204 L308 I315	A196-V200 WeakPolarHBondContact O-CG2 3.2Å; A196-V200 PolarHBondContact O-N 3.42Å; A197-V200 PolarHBondContact O-N 3.28Å; L198-V200 VanDerWaalsContact C-N 3.31Å; L198-V200 PolarHBondContact O-N 3.25Å; V200-I202 VanDerWaalsContact C-N 3.34Å; V200-I202 PolarHBondContact O-N 2.97Å; V200-I203 PolarHBondContact O-N 3.31Å; V200-T204 WeakPolarHBondContact O-CB 3.39Å; V200-T204 PolarHBondContact O-N 3.17Å; V200-T204 PolarHBondContact O-OG1 3.02Å; V200-L308 HydrophobicContact CG1-CD1 4.16Å; V200-L308 HydrophobicContact CG1-CD2 4.27Å; V200-I315 HydrophobicContact CG1-CD1 4.47Å
201	I	92.9	Very high	88.2	Confident	0 Å²	0	51.8 Å²	51.8	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-57.6	-46.8	178	-67.7	166.3	0	0	0	111.2	F59 A197 L198 I199 T204 G205 T280 A283 Y284 A300 F303 I315	F59-I201 HydrophobicContact CE1-CD1 4.41Å; A197-I201 WeakPolarHBondContact O-CG1 3.36Å; A197-I201 PolarHBondContact O-N 3.47Å; A197-I201 VanDerWaalsContact O-N 3.12Å; L198-I201 HydrophobicContact CD2-CD1 4.46Å; L198-I201 PolarHBondContact O-N 2.85Å; I199-I201 PolarHBondContact O-N 3.16Å; I201-T204 PolarHBondContact O-N 3.48Å; I201-G205 PolarHBondContact O-N 2.98Å; I201-T280 HydrophobicContact CG2-CG2 4.22Å; I201-A283 HydrophobicContact CG2-CB 3.95Å; I201-A283 WeakPolarHBondContact O-CB 3.47Å; I201-Y284 HydrophobicContact CD1-CE1 4.3Å; I201-Y284 HydrophobicContact CG2-CD1 4.21Å; I201-Y284 HydrophobicContact CG2-CE1 3.71Å; I201-A300 HydrophobicContact CD1-CB 4.08Å; I201-F303 HydrophobicContact CB-CE1 4.24Å; I201-F303 HydrophobicContact CG1-CD1 4.21Å; I201-F303 HydrophobicContact CG1-CE1 4.19Å; I201-F303 HydrophobicContact CG2-CD1 4.24Å; I201-F303 HydrophobicContact CG2-CE1 3.96Å; I201-F303 HydrophobicContact CG2-CZ 4.16Å; I201-I315 HydrophobicContact CD1-CD1 4.29Å; I201-I315 HydrophobicContact CG1-CD1 4.06Å
202	I	95.2	Very high	89.1	Confident	19 Å²	19	52.9 Å²	52.9	10%	0.097	30%	0.299	C	S	.	.	H	α-helix	trans	-63.2	-48.7	-179	-69.1	166.2	0	0	0	111.1	L198 I199 V200 T204 G205 I206 I276 L279	L198-I202 VanDerWaalsContact O-CG1 3.26Å; L198-I202 WeakPolarHBondContact O-CG1 3.41Å; L198-I202 PolarHBondContact O-N 3.29Å; I199-I202 PolarHBondContact O-N 2.96Å; V200-I202 VanDerWaalsContact C-N 3.34Å; V200-I202 PolarHBondContact O-N 2.97Å; I202-T204 PolarHBondContact O-N 3.03Å; I202-G205 PolarHBondContact O-N 3.18Å; I202-I206 HydrophobicContact CG2-CD1 3.8Å; I202-I206 HydrophobicContact CG2-CG1 4.48Å; I202-I206 WeakPolarHBondContact O-CG1 3.25Å; I202-I206 PolarHBondContact O-N 3.46Å; I202-I276 HydrophobicContact CD1-CG2 4.16Å; I202-L279 HydrophobicContact CD1-CB 3.96Å; I202-L279 HydrophobicContact CG1-CB 3.92Å; I202-L279 HydrophobicContact CG2-CB 4.01Å; I202-L279 HydrophobicContact CG2-CD1 4.15Å
203	I	94.9	Very high	89.8	Confident	99 Å²	99	50.8 Å²	50.8	51%	0.508	29%	0.291	S	S	.	.	H	α-helix	trans	-61.8	-46.8	-179.6	-68.9	172.2	0	0	0	110.2	I199 V200 G205 I206 V207	I199-I203 HydrophobicContact CG2-CD1 3.54Å; I199-I203 HydrophobicContact CG2-CG1 4.19Å; I199-I203 WeakPolarHBondContact O-CB 3.43Å; I199-I203 VanDerWaalsContact O-CG1 3.29Å; I199-I203 WeakPolarHBondContact O-CG1 3.48Å; I199-I203 PolarHBondContact O-N 2.96Å; V200-I203 PolarHBondContact O-N 3.31Å; I203-G205 VanDerWaalsContact C-N 3.32Å; I203-G205 PolarHBondContact O-N 3.45Å; I203-I206 PolarHBondContact O-N 3.27Å; I203-V207 HydrophobicContact CG2-CG2 4.46Å; I203-V207 WeakPolarHBondContact O-CG2 3.32Å; I203-V207 PolarHBondContact O-N 2.77Å
204	T	93.3	Very high	90.4	Very high	26 Å²	26	51.7 Å²	51.7	16%	0.16	29%	0.293	C	S	.	.	H	α-helix	trans	-60	-42.6	177.5	-59.7	0	0	0	0	111.5	V200 I201 I202 V207 K208 F303 T307 L308	V200-T204 WeakPolarHBondContact O-CB 3.39Å; V200-T204 PolarHBondContact O-N 3.17Å; V200-T204 PolarHBondContact O-OG1 3.02Å; I201-T204 PolarHBondContact O-N 3.48Å; I202-T204 PolarHBondContact O-N 3.03Å; T204-V207 PolarHBondContact O-N 3.35Å; T204-K208 WeakPolarHBondContact O-CG 3.31Å; T204-K208 PolarHBondContact O-N 3.1Å; T204-F303 HydrophobicContact CG2-CE1 4.06Å; T204-F303 HydrophobicContact CG2-CZ 3.87Å; T204-T307 HydrophobicContact CG2-CG2 4Å; T204-L308 HydrophobicContact CG2-CD2 4.31Å
205	G	93.9	Very high	90.8	Very high	1 Å²	1	56.2 Å²	56.2	1%	0.01	32%	0.318	C	S	.	.	H	α-helix	trans	-61.1	-45.5	175.4	0	0	0	0	0	113	I201 I202 I203 V207 K208 L209	I201-G205 PolarHBondContact O-N 2.98Å; I202-G205 PolarHBondContact O-N 3.18Å; I203-G205 VanDerWaalsContact C-N 3.32Å; I203-G205 PolarHBondContact O-N 3.45Å; G205-V207 PolarHBondContact O-N 2.99Å; G205-K208 PolarHBondContact O-N 3.11Å; G205-L209 WeakPolarHBondContact O-CG 3.37Å; G205-L209 PolarHBondContact O-N 3.04Å
206	I	94.4	Very high	91	Very high	83 Å²	83	56.1 Å²	56.1	43%	0.426	32%	0.315	S	S	.	.	H	α-helix	trans	-61.8	-43.7	176.5	-67.7	167.8	0	0	0	110.8	I202 I203 K208 L209 C210	I202-I206 HydrophobicContact CG2-CD1 3.8Å; I202-I206 HydrophobicContact CG2-CG1 4.48Å; I202-I206 WeakPolarHBondContact O-CG1 3.25Å; I202-I206 PolarHBondContact O-N 3.46Å; I203-I206 PolarHBondContact O-N 3.27Å; I206-K208 VanDerWaalsContact C-N 3.31Å; I206-K208 PolarHBondContact O-N 3.42Å; I206-L209 WeakPolarHBondContact O-CB 3.46Å; I206-L209 PolarHBondContact O-N 3.34Å; I206-C210 PolarHBondContact O-N 3.02Å; I206-C210 PolarHBondContact O-SG 3.4Å; I206-C210 VanDerWaalsContact O-SG 3.36Å
207	V	94.4	Very high	91.1	Very high	70 Å²	70	56.1 Å²	56.1	42%	0.424	31%	0.306	S	S	.	.	H	α-helix	trans	-60.1	-42.4	176.5	170.6	0	0	0	0	111	I203 T204 G205 C210 Q211	I203-V207 HydrophobicContact CG2-CG2 4.46Å; I203-V207 WeakPolarHBondContact O-CG2 3.32Å; I203-V207 PolarHBondContact O-N 2.77Å; T204-V207 PolarHBondContact O-N 3.35Å; G205-V207 PolarHBondContact O-N 2.99Å; V207-C210 PolarHBondContact O-N 3.48Å; V207-Q211 WeakPolarHBondContact O-CG 3.41Å; V207-Q211 PolarHBondContact O-N 2.75Å
208	K	92.8	Very high	91.1	Very high	43 Å²	43	63 Å²	63	19%	0.187	34%	0.335	C	S	.	.	H	α-helix	trans	-64.8	-40.5	176.7	-72.7	-74.4	-179.7	-177.8	0	112.4	T204 G205 I206 C210 Q211 G212 Y213 V287	T204-K208 WeakPolarHBondContact O-CG 3.31Å; T204-K208 PolarHBondContact O-N 3.1Å; G205-K208 PolarHBondContact O-N 3.11Å; I206-K208 VanDerWaalsContact C-N 3.31Å; I206-K208 PolarHBondContact O-N 3.42Å; K208-C210 VanDerWaalsContact C-N 3.35Å; K208-C210 PolarHBondContact O-N 2.9Å; K208-Q211 WeakPolarHBondContact O-CB 3.41Å; K208-Q211 PolarHBondContact O-N 2.84Å; K208-Q211 VanDerWaalsContact O-N 3.13Å; K208-G212 PolarHBondContact O-N 3.41Å; K208-Y213 HydrophobicContact CB-CD2 4.46Å; K208-Y213 HydrophobicContact CD-CD2 4.07Å; K208-Y213 HydrophobicContact CD-CE2 4.07Å; K208-Y213 WeakPolarHBondContact O-CB 3.42Å; K208-Y213 WeakPolarHBondContact O-CD2 3.4Å; K208-Y213 PolarHBondContact O-N 3.36Å; K208-V287 HydrophobicContact CB-CG2 4.06Å; K208-V287 HydrophobicContact CG-CG2 3.85Å
209	L	92.9	Very high	90.8	Very high	46 Å²	46	66.3 Å²	66.3	24%	0.241	36%	0.359	C	S	.	.	H	α-helix	trans	-59.7	-45	171.9	-73.1	171.3	0	0	0	111.7	G205 I206 Q211 G212 T214 F217 V282 A286	G205-L209 WeakPolarHBondContact O-CG 3.37Å; G205-L209 PolarHBondContact O-N 3.04Å; I206-L209 WeakPolarHBondContact O-CB 3.46Å; I206-L209 PolarHBondContact O-N 3.34Å; L209-Q211 PolarHBondContact O-N 3.49Å; L209-G212 PolarHBondContact O-N 3.46Å; L209-T214 HydrophobicContact CD2-CG2 4.17Å; L209-F217 HydrophobicContact CD2-CD2 4.09Å; L209-F217 HydrophobicContact CD2-CE2 3.66Å; L209-V282 HydrophobicContact CD1-CG1 3.79Å; L209-A286 HydrophobicContact CD1-CB 4.48Å; L209-A286 HydrophobicContact CD2-CB 3.71Å; L209-A286 HydrophobicContact CG-CB 3.79Å
210	C	92.7	Very high	90.7	Very high	109 Å²	109	63.3 Å²	63.3	74%	0.736	35%	0.345	S	S	*	.	H	α-helix	trans	-64.1	-25.4	176	-69.6	0	0	0	0	113.4	I206 V207 K208 G212	I206-C210 PolarHBondContact O-N 3.02Å; I206-C210 PolarHBondContact O-SG 3.4Å; I206-C210 VanDerWaalsContact O-SG 3.36Å; V207-C210 PolarHBondContact O-N 3.48Å; K208-C210 VanDerWaalsContact C-N 3.35Å; K208-C210 PolarHBondContact O-N 2.9Å; C210-G212 PolarHBondContact O-N 2.98Å
211	Q	92.3	Very high	90.7	Very high	117 Å²	117	66.8 Å²	66.8	55%	0.547	36%	0.356	S	S	.	.	T	Hydrogen-bonded Turn	trans	-78.8	-3.2	173	-71.5	172.4	1.2	0	0	113.4	V207 K208 L209 Y213	V207-Q211 WeakPolarHBondContact O-CG 3.41Å; V207-Q211 PolarHBondContact O-N 2.75Å; K208-Q211 WeakPolarHBondContact O-CB 3.41Å; K208-Q211 PolarHBondContact O-N 2.84Å; K208-Q211 VanDerWaalsContact O-N 3.13Å; L209-Q211 PolarHBondContact O-N 3.49Å; Q211-Y213 HydrophobicContact CB-CD2 3.94Å; Q211-Y213 HydrophobicContact CB-CE2 4.06Å
212	G	89.2	Confident	90.6	Very high	43 Å²	43	74 Å²	74	44%	0.443	39%	0.389	S	S	.	.	T	Hydrogen-bonded Turn	trans	99.5	4.9	175.7	0	0	0	0	0	115.4	K208 L209 C210 T214	K208-G212 PolarHBondContact O-N 3.41Å; L209-G212 PolarHBondContact O-N 3.46Å; C210-G212 PolarHBondContact O-N 2.98Å; G212-T214 PolarHBondContact O-N 2.75Å; G212-T214 PolarHBondContact O-OG1 2.83Å
213	Y	88.3	Confident	90.2	Very high	123 Å²	123	75.9 Å²	75.9	48%	0.482	41%	0.414	S	S	.	.			trans	-71.7	76	176.7	-70.1	-100.6	0	0	0	111.1	K208 Q211	K208-Y213 HydrophobicContact CB-CD2 4.46Å; K208-Y213 HydrophobicContact CD-CD2 4.07Å; K208-Y213 HydrophobicContact CD-CE2 4.07Å; K208-Y213 WeakPolarHBondContact O-CB 3.42Å; K208-Y213 WeakPolarHBondContact O-CD2 3.4Å; K208-Y213 PolarHBondContact O-N 3.36Å; Q211-Y213 HydrophobicContact CB-CD2 3.94Å; Q211-Y213 HydrophobicContact CB-CE2 4.06Å
214	T	88.5	Confident	90.2	Very high	56 Å²	56	72.8 Å²	72.8	34%	0.344	40%	0.401	S	S	.	.			trans	-122.8	2.4	-173.8	55.4	0	0	0	0	113.2	L209 G212 N216 F217 K218	L209-T214 HydrophobicContact CD2-CG2 4.17Å; G212-T214 PolarHBondContact O-N 2.75Å; G212-T214 PolarHBondContact O-OG1 2.83Å; T214-N216 VanDerWaalsContact C-N 3.3Å; T214-N216 PolarHBondContact O-N 2.91Å; T214-F217 PolarHBondContact O-N 2.82Å; T214-K218 PolarHBondContact O-N 3.19Å
215	D	85.7	Confident	90.1	Very high	106 Å²	106	72.5 Å²	72.5	57%	0.567	40%	0.4	S	S	*	.	H	α-helix	trans	-59.5	-41.2	-174.3	-68.5	-41	0	0	0	112.3	F217 K218	D215-F217 PolarHBondContact O-N 3.29Å; D215-F217 VanDerWaalsContact O-N 3.13Å; D215-K218 PolarHBondContact O-N 3.47Å; D215-K218 WeakPolarHBondContact OD1-CE 3.41Å; D215-K218 IonicContact OD1-NZ 2.98Å; D215-K218 PolarHBondContact OD1-NZ 3.41Å
216	N	85.8	Confident	90	Very high	37 Å²	37	78.7 Å²	78.7	20%	0.198	44%	0.438	C	S	.	.	H	α-helix	trans	-60	-23.8	175.6	-74.5	-19.9	0	0	0	113.2	Y72 T214 Y285 L288 D289	Y72-N216 HydrophobicContact CD2-CB 4.22Å; Y72-N216 VanDerWaalsContact CD2-O 3.24Å; Y72-N216 WeakPolarHBondContact CD2-O 3.14Å; Y72-N216 HydrophobicContact CE2-CB 3.68Å; T214-N216 VanDerWaalsContact C-N 3.3Å; T214-N216 PolarHBondContact O-N 2.91Å; N216-Y285 VanDerWaalsContact CB-O 3.28Å; N216-Y285 WeakPolarHBondContact CB-O 3.16Å; N216-Y285 PolarHBondContact ND2-O 3.18Å; N216-L288 PolarHBondContact ND2-O 2.97Å; N216-D289 PolarHBondContact ND2-OD1 2.93Å; N216-D289 PolarHBondContact OD1-OD1 3.41Å
217	F	87.8	Confident	89.9	Confident	51 Å²	51	78.3 Å²	78.3	22%	0.224	44%	0.437	C	S	.	.	H	α-helix	trans	-90.7	-14	-179.2	-63.3	-77.7	0	0	0	114.6	L76 L209 T214 D215 S219 S220 V282 A286	L76-F217 HydrophobicContact CD1-CE1 4.48Å; L209-F217 HydrophobicContact CD2-CD2 4.09Å; L209-F217 HydrophobicContact CD2-CE2 3.66Å; T214-F217 PolarHBondContact O-N 2.82Å; D215-F217 PolarHBondContact O-N 3.29Å; D215-F217 VanDerWaalsContact O-N 3.13Å; F217-S219 VanDerWaalsContact C-N 3.33Å; F217-S219 PolarHBondContact O-N 2.97Å; F217-S220 VanDerWaalsContact C-OG 3.27Å; F217-S220 WeakPolarHBondContact CA-OG 3.44Å; F217-S220 PolarHBondContact O-N 2.96Å; F217-S220 PolarHBondContact O-OG 3.33Å; F217-V282 HydrophobicContact CZ-CG1 4.16Å; F217-A286 HydrophobicContact CE2-CB 3.94Å; F217-A286 HydrophobicContact CZ-CB 4.42Å
218	K	85.5	Confident	89.8	Confident	149 Å²	149	77.7 Å²	77.7	65%	0.648	43%	0.434	S	S	*	.	H	α-helix	trans	-63.7	-35.4	-174.3	-71.2	176	179.5	165.5	0	113.4	T214 D215	T214-K218 PolarHBondContact O-N 3.19Å; D215-K218 PolarHBondContact O-N 3.47Å; D215-K218 WeakPolarHBondContact OD1-CE 3.41Å; D215-K218 IonicContact OD1-NZ 2.98Å; D215-K218 PolarHBondContact OD1-NZ 3.41Å
219	S	84.8	Confident	89.8	Confident	73 Å²	73	75.7 Å²	75.7	51%	0.51	43%	0.426	S	S	.	.	T	Hydrogen-bonded Turn	trans	-121.6	42.8	177.1	-63.5	0	0	0	0	111.8	F217 F221 Q222	F217-S219 VanDerWaalsContact C-N 3.33Å; F217-S219 PolarHBondContact O-N 2.97Å; S219-F221 PolarHBondContact O-N 3.1Å; S219-Q222 WeakPolarHBondContact O-CB 3.33Å; S219-Q222 PolarHBondContact O-N 3.28Å
220	S	88.2	Confident	89.8	Confident	22 Å²	22	76.1 Å²	76.1	15%	0.154	43%	0.428	C	S	.	.	T	Hydrogen-bonded Turn	trans	-52.9	-29.7	-169.6	-66.8	0	0	0	0	115.4	S71 Y72 G73 F217	S71-S220 VanDerWaalsContact CB-O 3.29Å; S71-S220 WeakPolarHBondContact CB-O 3.33Å; S71-S220 PolarHBondContact OG-O 3.09Å; Y72-S220 PolarHBondContact N-O 3.25Å; G73-S220 WeakPolarHBondContact CA-O 3.36Å; G73-S220 PolarHBondContact N-O 3.38Å; F217-S220 VanDerWaalsContact C-OG 3.27Å; F217-S220 WeakPolarHBondContact CA-OG 3.44Å; F217-S220 PolarHBondContact O-N 2.96Å; F217-S220 PolarHBondContact O-OG 3.33Å
221	F	92	Very high	89.9	Confident	129 Å²	129	73.3 Å²	73.3	57%	0.566	41%	0.406	S	S	*	.	T	Hydrogen-bonded Turn	trans	-100.5	0.2	-177	-67.3	-82.8	0	0	0	113.9	V77 S219 G223 S224	V77-F221 HydrophobicContact CG2-CE1 4.27Å; V77-F221 HydrophobicContact CG2-CZ 4.5Å; S219-F221 PolarHBondContact O-N 3.1Å; F221-G223 PolarHBondContact O-N 3.37Å; F221-S224 WeakPolarHBondContact O-CB 3.36Å; F221-S224 PolarHBondContact O-N 3.38Å; F221-S224 PolarHBondContact O-OG 3.36Å
222	Q	89.8	Confident	89.9	Confident	151 Å²	151	67.8 Å²	67.8	71%	0.706	38%	0.38	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.5	131.7	-179.9	-171.9	172.5	10.1	0	0	110.1	S219 S224	S219-Q222 WeakPolarHBondContact O-CB 3.33Å; S219-Q222 PolarHBondContact O-N 3.28Å; Q222-S224 VanDerWaalsContact C-N 3.3Å; Q222-S224 PolarHBondContact O-N 3.28Å
223	G	87.8	Confident	90.1	Very high	59 Å²	59	66.3 Å²	66.3	61%	0.608	36%	0.362	S	S	*	.	T	Hydrogen-bonded Turn	trans	78.4	8.2	-179.4	0	0	0	0	0	115.1	A70 F221 S225	A70-G223 VanDerWaalsContact CB-O 3.24Å; A70-G223 WeakPolarHBondContact CB-O 3.11Å; F221-G223 PolarHBondContact O-N 3.37Å; G223-S225 PolarHBondContact O-N 3.01Å
224	S	93.3	Very high	90.5	Very high	34 Å²	34	60.5 Å²	60.5	24%	0.238	34%	0.339	C	S	.	.			trans	-53.9	131.9	178.7	-59.2	0	0	0	0	111.8	S69 S71 F221 Q222	S69-S224 WeakPolarHBondContact O-CA 3.09Å; S71-S224 WeakPolarHBondContact CB-OG 3.27Å; S71-S224 PolarHBondContact OG-OG 3.33Å; F221-S224 WeakPolarHBondContact O-CB 3.36Å; F221-S224 PolarHBondContact O-N 3.38Å; F221-S224 PolarHBondContact O-OG 3.36Å; Q222-S224 VanDerWaalsContact C-N 3.3Å; Q222-S224 PolarHBondContact O-N 3.28Å
225	S	92.3	Very high	90.8	Very high	21 Å²	21	58.7 Å²	58.7	15%	0.147	33%	0.327	C	S	.	.			trans	-64.3	141.2	172.9	-172.1	0	0	0	0	110.7	Y68 S69 L74 G223 D227 D230	Y68-S225 VanDerWaalsContact O-CB 3.25Å; Y68-S225 WeakPolarHBondContact O-CB 3.18Å; S69-S225 PolarHBondContact O-N 3.02Å; L74-S225 WeakPolarHBondContact CD2-O 3.3Å; G223-S225 PolarHBondContact O-N 3.01Å; S225-D227 PolarHBondContact OG-N 2.94Å; S225-D230 WeakPolarHBondContact OG-CB 3.48Å; S225-D230 PolarHBondContact OG-OD2 3.22Å
226	T	91.9	Very high	91.3	Very high	131 Å²	131	53.7 Å²	53.7	80%	0.804	30%	0.3	S	S	*	.			trans	-111.9	-3.3	174.3	54.7	0	0	0	0	111.9	P228	T226-P228 WeakPolarHBondContact O-CD 3.48Å
227	D	93	Very high	91.7	Very high	74 Å²	74	52 Å²	52	40%	0.396	29%	0.291	S	S	.	.			trans	-73.3	126.1	179	-176.3	63	0	0	0	110	S225 G229 D230 I231	S225-D227 PolarHBondContact OG-N 2.94Å; D227-G229 PolarHBondContact O-N 3.19Å; D227-G229 WeakPolarHBondContact OD2-CA 3.33Å; D227-G229 PolarHBondContact OD2-N 3.46Å; D227-D230 HydrophobicContact CB-CB 4.27Å; D227-D230 PolarHBondContact O-N 3.36Å; D227-D230 PolarHBondContact OD2-N 3.42Å; D227-D230 VanDerWaalsContact OD2-N 3.14Å; D227-I231 WeakPolarHBondContact O-CG1 3.25Å; D227-I231 PolarHBondContact O-N 3.28Å
228	P	91.6	Very high	92.1	Very high	58 Å²	58	49.5 Å²	49.5	38%	0.377	28%	0.28	S	S	.	.	H	α-helix	trans	-60.2	-29.6	177.9	-24.5	34.7	0	0	0	113.3	T226 I231 A232 V437	T226-P228 WeakPolarHBondContact O-CD 3.48Å; P228-I231 PolarHBondContact O-N 3.16Å; P228-A232 PolarHBondContact O-N 3.25Å; P228-V437 WeakPolarHBondContact O-CG1 3.36Å
229	G	91.7	Very high	92.5	Very high	1 Å²	1	42.5 Å²	42.5	1%	0.01	25%	0.25	C	C	.	.	H	α-helix	trans	-64.2	-51.8	177.5	0	0	0	0	0	112.4	D227 I231 A232 L233 S441	D227-G229 PolarHBondContact O-N 3.19Å; D227-G229 WeakPolarHBondContact OD2-CA 3.33Å; D227-G229 PolarHBondContact OD2-N 3.46Å; G229-I231 VanDerWaalsContact C-N 3.29Å; G229-I231 PolarHBondContact O-N 2.96Å; G229-A232 PolarHBondContact O-N 2.88Å; G229-A232 VanDerWaalsContact O-N 3.11Å; G229-L233 WeakPolarHBondContact O-CG 3.42Å; G229-L233 PolarHBondContact O-N 3.36Å; G229-S441 WeakPolarHBondContact CA-OG 3.43Å
230	D	93.4	Very high	92.9	Very high	54 Å²	54	39.3 Å²	39.3	29%	0.289	23%	0.227	S	C	.	.	H	α-helix	trans	-55.9	-44.9	173.6	-73.5	-19.4	0	0	0	111.5	Y68 S225 D227 A232 L233 A234	Y68-D230 VanDerWaalsContact CB-O 3.31Å; Y68-D230 WeakPolarHBondContact CB-O 3.44Å; Y68-D230 WeakPolarHBondContact O-CB 3.38Å; S225-D230 WeakPolarHBondContact OG-CB 3.48Å; S225-D230 PolarHBondContact OG-OD2 3.22Å; D227-D230 HydrophobicContact CB-CB 4.27Å; D227-D230 PolarHBondContact O-N 3.36Å; D227-D230 PolarHBondContact OD2-N 3.42Å; D227-D230 VanDerWaalsContact OD2-N 3.14Å; D230-A232 VanDerWaalsContact C-N 3.3Å; D230-A232 PolarHBondContact O-N 3.22Å; D230-L233 PolarHBondContact O-N 3.3Å; D230-A234 WeakPolarHBondContact O-CB 3.37Å; D230-A234 PolarHBondContact O-N 2.94Å
231	I	94.5	Very high	93.2	Very high	51 Å²	51	38.3 Å²	38.3	26%	0.262	22%	0.22	S	C	.	.	H	α-helix	trans	-61.5	-39.7	178.5	-64.7	167.8	0	0	0	111.2	D227 P228 G229 L235	D227-I231 WeakPolarHBondContact O-CG1 3.25Å; D227-I231 PolarHBondContact O-N 3.28Å; P228-I231 PolarHBondContact O-N 3.16Å; G229-I231 VanDerWaalsContact C-N 3.29Å; G229-I231 PolarHBondContact O-N 2.96Å; I231-L235 HydrophobicContact CG2-CD1 4.22Å; I231-L235 WeakPolarHBondContact O-CB 3.27Å; I231-L235 WeakPolarHBondContact O-CG 3.37Å; I231-L235 PolarHBondContact O-N 3.42Å
232	A	93.8	Very high	93.2	Very high	0 Å²	0	32.2 Å²	32.2	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-67.3	-41.5	177.5	0	0	0	0	0	112.5	P228 G229 D230 L235 Y236 F433 V437 P438	P228-A232 PolarHBondContact O-N 3.25Å; G229-A232 PolarHBondContact O-N 2.88Å; G229-A232 VanDerWaalsContact O-N 3.11Å; D230-A232 VanDerWaalsContact C-N 3.3Å; D230-A232 PolarHBondContact O-N 3.22Å; A232-L235 WeakPolarHBondContact O-CB 3.44Å; A232-L235 PolarHBondContact O-N 2.65Å; A232-Y236 WeakPolarHBondContact O-CD1 3.24Å; A232-Y236 PolarHBondContact O-N 3.44Å; A232-F433 HydrophobicContact CB-CE1 4.09Å; A232-F433 HydrophobicContact CB-CZ 4.31Å; A232-V437 HydrophobicContact CB-CB 4.01Å; A232-V437 HydrophobicContact CB-CG1 3.49Å; A232-V437 VanDerWaalsContact CB-CG1 3.49Å; A232-P438 HydrophobicContact CB-CG 4.19Å
233	L	93.3	Very high	93.1	Very high	13 Å²	13	26 Å²	26	7%	0.068	17%	0.166	C	C	.	.	H	α-helix	trans	-70.3	-34.4	177.1	-64.8	178.3	0	0	0	112.4	Y68 G229 D230 Y236 S237 D442	Y68-L233 HydrophobicContact CD1-CB 3.91Å; Y68-L233 HydrophobicContact CD1-CD1 4.07Å; Y68-L233 HydrophobicContact CD2-CB 3.77Å; Y68-L233 HydrophobicContact CE1-CB 3.91Å; Y68-L233 HydrophobicContact CE1-CD1 3.54Å; Y68-L233 HydrophobicContact CE1-CG 4.38Å; Y68-L233 HydrophobicContact CE2-CB 3.79Å; Y68-L233 HydrophobicContact CG-CB 3.86Å; G229-L233 WeakPolarHBondContact O-CG 3.42Å; G229-L233 PolarHBondContact O-N 3.36Å; D230-L233 PolarHBondContact O-N 3.3Å; L233-Y236 HydrophobicContact CD2-CD2 4.19Å; L233-Y236 WeakPolarHBondContact O-CB 3.34Å; L233-Y236 PolarHBondContact O-N 3.27Å; L233-S237 PolarHBondContact O-N 3.31Å; L233-S237 VanDerWaalsContact O-N 3.12Å; L233-S237 PolarHBondContact O-OG 2.82Å; L233-D442 HydrophobicContact CD2-CB 4.31Å
234	A	95.8	Very high	92.8	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-63.4	-44.4	169.8	0	0	0	0	0	111	V65 I78 D230 Y236 S237 A238	V65-A234 HydrophobicContact CG1-CB 4.48Å; I78-A234 HydrophobicContact CD1-CB 3.65Å; I78-A234 HydrophobicContact CG2-CB 4.14Å; D230-A234 WeakPolarHBondContact O-CB 3.37Å; D230-A234 PolarHBondContact O-N 2.94Å; A234-Y236 VanDerWaalsContact C-N 3.33Å; A234-Y236 PolarHBondContact O-N 2.87Å; A234-S237 WeakPolarHBondContact O-CB 3.47Å; A234-S237 PolarHBondContact O-N 2.89Å; A234-A238 PolarHBondContact O-N 2.96Å
235	L	95.8	Very high	92.5	Very high	19 Å²	19	22.2 Å²	22.2	10%	0.099	13%	0.132	C	C	.	.	H	α-helix	trans	-61.8	-39.5	174.5	-81.7	167.5	0	0	0	111.6	I78 I81 I231 A232 S237 A238 L239 F433 L434	I78-L235 HydrophobicContact CG2-CD2 3.95Å; I78-L235 HydrophobicContact CG2-CG 4.12Å; I81-L235 HydrophobicContact CG2-CD2 4.06Å; I231-L235 HydrophobicContact CG2-CD1 4.22Å; I231-L235 WeakPolarHBondContact O-CB 3.27Å; I231-L235 WeakPolarHBondContact O-CG 3.37Å; I231-L235 PolarHBondContact O-N 3.42Å; A232-L235 WeakPolarHBondContact O-CB 3.44Å; A232-L235 PolarHBondContact O-N 2.65Å; L235-S237 VanDerWaalsContact C-N 3.31Å; L235-S237 PolarHBondContact O-N 2.7Å; L235-A238 PolarHBondContact O-N 3.46Å; L235-L239 HydrophobicContact CB-CD1 4.4Å; L235-L239 WeakPolarHBondContact O-CB 3.32Å; L235-L239 WeakPolarHBondContact O-CG 3.46Å; L235-L239 PolarHBondContact O-N 3.46Å; L235-F433 HydrophobicContact CD1-CE1 4.09Å; L235-L434 HydrophobicContact CB-CD2 3.98Å; L235-L434 HydrophobicContact CD1-CD2 4.31Å
236	Y	94.5	Very high	92.2	Very high	1 Å²	1	21.7 Å²	21.7	0%	0.004	13%	0.128	C	C	.	.	H	α-helix	trans	-55.7	-47.6	173.1	-81.6	12	0	0	0	111.7	A232 L233 A234 A238 L239 F240 N386 S389 F390 L434 P438	A232-Y236 WeakPolarHBondContact O-CD1 3.24Å; A232-Y236 PolarHBondContact O-N 3.44Å; L233-Y236 HydrophobicContact CD2-CD2 4.19Å; L233-Y236 WeakPolarHBondContact O-CB 3.34Å; L233-Y236 PolarHBondContact O-N 3.27Å; A234-Y236 VanDerWaalsContact C-N 3.33Å; A234-Y236 PolarHBondContact O-N 2.87Å; Y236-A238 PolarHBondContact O-N 2.87Å; Y236-L239 PolarHBondContact O-N 3.31Å; Y236-F240 WeakPolarHBondContact O-CB 3.34Å; Y236-F240 PolarHBondContact O-N 3.18Å; Y236-N386 HydrophobicContact CD2-CB 4.37Å; Y236-S389 VanDerWaalsContact CD2-CB 3.45Å; Y236-S389 VanDerWaalsContact CG-CB 3.45Å; Y236-F390 HydrophobicContact CE2-CB 4.29Å; Y236-F390 VanDerWaalsContact OH-CA 3.3Å; Y236-F390 WeakPolarHBondContact OH-CA 3.27Å; Y236-L434 HydrophobicContact CD1-CD2 4.01Å; Y236-L434 HydrophobicContact CE1-CB 4.05Å; Y236-L434 HydrophobicContact CE1-CD2 3.94Å; Y236-L434 VanDerWaalsContact CE1-O 3.25Å; Y236-L434 WeakPolarHBondContact CE1-O 3.44Å; Y236-L434 VanDerWaalsContact CZ-O 3.22Å; Y236-L434 PolarHBondContact OH-O 2.79Å; Y236-P438 HydrophobicContact CE1-CG 4.15Å; Y236-P438 HydrophobicContact CE2-CB 4.24Å; Y236-P438 HydrophobicContact CE2-CG 3.95Å; Y236-P438 WeakPolarHBondContact OH-CG 3.18Å
237	S	94.8	Very high	91.6	Very high	0 Å²	0	17.2 Å²	17.2	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-60.3	-47.4	177.3	-64.4	0	0	0	0	111.7	S61 L233 A234 L235	S61-S237 WeakPolarHBondContact CB-O 3.44Å; S61-S237 PolarHBondContact OG-O 2.89Å; L233-S237 PolarHBondContact O-N 3.31Å; L233-S237 VanDerWaalsContact O-N 3.12Å; L233-S237 PolarHBondContact O-OG 2.82Å; A234-S237 WeakPolarHBondContact O-CB 3.47Å; A234-S237 PolarHBondContact O-N 2.89Å; L235-S237 VanDerWaalsContact C-N 3.31Å; L235-S237 PolarHBondContact O-N 2.7Å
238	A	95.9	Very high	90.9	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-64.7	-44.3	177.8	0	0	0	0	0	112	V65 I78 W79 A234 L235 Y236 F240 S241 Y242	V65-A238 HydrophobicContact CG2-CB 3.93Å; I78-A238 HydrophobicContact CG2-CB 4.08Å; W79-A238 HydrophobicContact CD2-CB 4.33Å; W79-A238 HydrophobicContact CE3-CB 4.34Å; A234-A238 PolarHBondContact O-N 2.96Å; L235-A238 PolarHBondContact O-N 3.46Å; Y236-A238 PolarHBondContact O-N 2.87Å; A238-F240 VanDerWaalsContact C-N 3.32Å; A238-F240 PolarHBondContact O-N 2.87Å; A238-S241 VanDerWaalsContact O-CB 3.28Å; A238-S241 WeakPolarHBondContact O-CB 3.2Å; A238-S241 PolarHBondContact O-N 3.23Å; A238-Y242 VanDerWaalsContact O-CD2 3.25Å; A238-Y242 WeakPolarHBondContact O-CD2 3.43Å; A238-Y242 PolarHBondContact O-N 3.44Å
239	L	94.6	Very high	90.5	Very high	1 Å²	1	11 Å²	11	1%	0.005	6%	0.064	C	C	.	.	H	α-helix	trans	-70.2	-27.3	-176.8	-73.6	178.3	0	0	0	113.4	G82 F85 L235 Y236 S241 Y242 S243 W393 L434	G82-L239 WeakPolarHBondContact O-CD2 3.24Å; F85-L239 HydrophobicContact CD1-CD1 3.85Å; F85-L239 HydrophobicContact CD1-CD2 3.62Å; F85-L239 HydrophobicContact CD1-CG 4.41Å; F85-L239 HydrophobicContact CE1-CD1 3.88Å; F85-L239 HydrophobicContact CE1-CD2 4.26Å; L235-L239 HydrophobicContact CB-CD1 4.4Å; L235-L239 WeakPolarHBondContact O-CB 3.32Å; L235-L239 WeakPolarHBondContact O-CG 3.46Å; L235-L239 PolarHBondContact O-N 3.46Å; Y236-L239 PolarHBondContact O-N 3.31Å; L239-S241 VanDerWaalsContact C-N 3.27Å; L239-S241 PolarHBondContact O-N 3.42Å; L239-Y242 CarbonylContact O-C 3.54Å; L239-Y242 PolarHBondContact O-N 2.84Å; L239-S243 PolarHBondContact O-N 3.44Å; L239-W393 HydrophobicContact CB-CZ2 3.62Å; L239-W393 HydrophobicContact CD1-CZ2 3.97Å; L239-W393 HydrophobicContact CD2-CH2 4.38Å; L239-W393 HydrophobicContact CD2-CZ2 4.07Å; L239-W393 HydrophobicContact CG-CZ2 4.09Å; L239-L434 HydrophobicContact CD1-CD1 3.51Å; L239-L434 HydrophobicContact CD1-CD2 4.14Å; L239-L434 HydrophobicContact CD1-CG 4.5Å
240	F	94.1	Very high	89.7	Confident	7 Å²	7	14 Å²	14	3%	0.031	8%	0.077	C	C	.	.	H	α-helix	trans	-57.6	-42.5	167	-178.9	-102.2	0	0	0	111.3	V137 Y236 A238 Y242 S243 I385 Y388	V137-F240 HydrophobicContact CB-CZ 3.93Å; V137-F240 HydrophobicContact CG1-CE1 3.6Å; V137-F240 HydrophobicContact CG1-CE2 4.43Å; V137-F240 HydrophobicContact CG1-CZ 3.47Å; V137-F240 VanDerWaalsContact CG1-CZ 3.47Å; Y236-F240 WeakPolarHBondContact O-CB 3.34Å; Y236-F240 PolarHBondContact O-N 3.18Å; A238-F240 VanDerWaalsContact C-N 3.32Å; A238-F240 PolarHBondContact O-N 2.87Å; F240-Y242 VanDerWaalsContact C-N 3.32Å; F240-Y242 PolarHBondContact O-N 3.45Å; F240-S243 WeakPolarHBondContact O-CB 3.47Å; F240-S243 PolarHBondContact O-N 3.25Å; F240-S243 PolarHBondContact O-OG 3.31Å; F240-I385 HydrophobicContact CB-CG2 3.9Å; F240-I385 HydrophobicContact CD1-CD1 4.22Å; F240-I385 HydrophobicContact CD1-CG1 4.23Å; F240-I385 HydrophobicContact CD2-CG1 4.35Å; F240-I385 HydrophobicContact CD2-CG2 4.43Å; F240-I385 HydrophobicContact CE1-CG1 4.45Å; F240-I385 HydrophobicContact CG-CG1 4.19Å; F240-I385 HydrophobicContact CG-CG2 4.15Å; F240-Y388 AromaticContact CD2-CD1 3.58Å; F240-Y388 HydrophobicContact CD2-CD1 3.58Å; F240-Y388 AromaticContact CD2-CE1 3.7Å; F240-Y388 HydrophobicContact CD2-CE1 3.7Å; F240-Y388 HydrophobicContact CD2-CG 4.3Å; F240-Y388 HydrophobicContact CE2-CD1 4.05Å; F240-Y388 HydrophobicContact CE2-CE1 4.22Å; F240-Y388 HydrophobicContact CE2-CG 4.35Å
241	S	93.6	Very high	88.8	Confident	1 Å²	1	12.2 Å²	12.2	1%	0.007	7%	0.068	C	C	.	.	H	α-helix	trans	-68.7	-29.2	175.3	-70	0	0	0	0	113.8	G57 I58 S61 W79 A238 L239 S243 Y277	G57-S241 WeakPolarHBondContact CA-OG 3.4Å; G57-S241 PolarHBondContact O-OG 2.63Å; I58-S241 PolarHBondContact N-OG 2.69Å; I58-S241 VanDerWaalsContact N-OG 3.14Å; S61-S241 WeakPolarHBondContact CB-OG 3.48Å; S61-S241 PolarHBondContact OG-OG 2.95Å; W79-S241 WeakPolarHBondContact CH2-OG 3.21Å; A238-S241 VanDerWaalsContact O-CB 3.28Å; A238-S241 WeakPolarHBondContact O-CB 3.2Å; A238-S241 PolarHBondContact O-N 3.23Å; L239-S241 VanDerWaalsContact C-N 3.27Å; L239-S241 PolarHBondContact O-N 3.42Å; S241-S243 VanDerWaalsContact C-N 3.32Å; S241-Y277 VanDerWaalsContact O-CE2 3.25Å; S241-Y277 WeakPolarHBondContact O-CE2 3.28Å; S241-Y277 PolarHBondContact O-OH 3.21Å
242	Y	92.2	Very high	87.9	Confident	0 Å²	0	10.1 Å²	10.1	0%	0	6%	0.057	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.4	-1.6	175.3	-72.6	-72.6	0	0	0	113.3	M53 W79 S86 A238 L239 F240 V273 Y277	M53-Y242 HydrophobicContact CE-CD1 3.73Å; M53-Y242 HydrophobicContact CE-CG 4.46Å; M53-Y242 VanDerWaalsContact CE-O 3.28Å; M53-Y242 WeakPolarHBondContact CE-O 3.26Å; W79-Y242 AromaticContact CE3-CE2 3.64Å; W79-Y242 HydrophobicContact CE3-CE2 3.64Å; W79-Y242 HydrophobicContact CZ3-CE2 4.05Å; W79-Y242 WeakPolarHBondContact O-CE2 3.14Å; W79-Y242 PolarHBondContact O-OH 3.14Å; S86-Y242 WeakPolarHBondContact OG-CB 3.44Å; A238-Y242 VanDerWaalsContact O-CD2 3.25Å; A238-Y242 WeakPolarHBondContact O-CD2 3.43Å; A238-Y242 PolarHBondContact O-N 3.44Å; L239-Y242 CarbonylContact O-C 3.54Å; L239-Y242 PolarHBondContact O-N 2.84Å; F240-Y242 VanDerWaalsContact C-N 3.32Å; F240-Y242 PolarHBondContact O-N 3.45Å; Y242-V273 HydrophobicContact CD1-CG1 4.24Å; Y242-V273 HydrophobicContact CE1-CG1 4.18Å; Y242-Y277 AromaticContact CD1-CD2 3.92Å; Y242-Y277 HydrophobicContact CD1-CD2 3.92Å; Y242-Y277 AromaticContact CD1-CE2 3.87Å; Y242-Y277 HydrophobicContact CD1-CE2 3.87Å; Y242-Y277 HydrophobicContact CD2-CD2 4.44Å; Y242-Y277 AromaticContact CE1-CD2 3.44Å; Y242-Y277 HydrophobicContact CE1-CD2 3.44Å; Y242-Y277 VanDerWaalsContact CE1-CD2 3.44Å; Y242-Y277 AromaticContact CE1-CE2 3.88Å; Y242-Y277 HydrophobicContact CE1-CE2 3.88Å; Y242-Y277 HydrophobicContact CE1-CG 4.43Å; Y242-Y277 HydrophobicContact CE2-CD2 4.02Å; Y242-Y277 HydrophobicContact CG-CD2 4.39Å; Y242-Y277 HydrophobicContact CG-CE2 4.24Å; Y242-Y277 AromaticContact CZ-CD2 3.49Å; Y242-Y277 VanDerWaalsContact CZ-CD2 3.49Å
243	S	86.9	Confident	87.1	Confident	21 Å²	21	13.4 Å²	13.4	15%	0.147	7%	0.073	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.2	153.3	178.1	68.5	0	0	0	0	112.1	M53 L239 F240 S241 Y388	M53-S243 WeakPolarHBondContact CA-O 3.32Å; L239-S243 PolarHBondContact O-N 3.44Å; F240-S243 WeakPolarHBondContact O-CB 3.47Å; F240-S243 PolarHBondContact O-N 3.25Å; F240-S243 PolarHBondContact O-OG 3.31Å; S241-S243 VanDerWaalsContact C-N 3.32Å; S243-Y388 WeakPolarHBondContact CB-OH 3.24Å
244	G	83.1	Confident	86.6	Confident	13 Å²	13	15.5 Å²	15.5	13%	0.134	8%	0.082	C	C	.	.	T	Hydrogen-bonded Turn	trans	103.9	-4.3	175	0	0	0	0	0	116	D246 T247	G244-D246 WeakPolarHBondContact CA-OD1 3.47Å; G244-D246 PolarHBondContact O-N 2.93Å; G244-T247 WeakPolarHBondContact O-CB 3.26Å; G244-T247 PolarHBondContact O-N 2.98Å; G244-T247 VanDerWaalsContact O-N 3.1Å; G244-T247 PolarHBondContact O-OG1 3.3Å
245	W	87	Confident	86	Confident	0 Å²	0	15.7 Å²	15.7	0%	0	8%	0.083	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.7	-24.2	171.4	52.6	-106.3	0	0	0	113.1	I49 M53 G89 A90 Y93 T247 M270 W393 M396	I49-W245 HydrophobicContact CG2-CB 4.43Å; M53-W245 HydrophobicContact CE-CB 4.43Å; M53-W245 HydrophobicContact CG-CB 4.41Å; M53-W245 HydrophobicContact SD-CB 3.87Å; G89-W245 VanDerWaalsContact C-CH2 3.5Å; A90-W245 VanDerWaalsContact CA-CE3 3.44Å; A90-W245 HydrophobicContact CB-CB 4.28Å; A90-W245 HydrophobicContact CB-CD2 3.8Å; A90-W245 HydrophobicContact CB-CE3 3.59Å; A90-W245 HydrophobicContact CB-CG 4.11Å; A90-W245 HydrophobicContact CB-CZ3 4.2Å; Y93-W245 AromaticContact CD1-CZ3 3.94Å; Y93-W245 HydrophobicContact CD1-CZ3 3.94Å; Y93-W245 AromaticContact CD2-CH2 3.61Å; Y93-W245 HydrophobicContact CD2-CH2 3.61Å; Y93-W245 AromaticContact CD2-CZ3 3.64Å; Y93-W245 HydrophobicContact CD2-CZ3 3.64Å; Y93-W245 AromaticContact CE2-CH2 3.98Å; Y93-W245 HydrophobicContact CE2-CH2 3.98Å; Y93-W245 HydrophobicContact CE2-CZ3 4.31Å; Y93-W245 AromaticContact CG-CH2 3.94Å; Y93-W245 HydrophobicContact CG-CH2 3.94Å; Y93-W245 AromaticContact CG-CZ3 3.44Å; Y93-W245 HydrophobicContact CG-CZ3 3.44Å; Y93-W245 VanDerWaalsContact CG-CZ3 3.44Å; W245-T247 PolarHBondContact O-N 3.41Å; W245-M270 HydrophobicContact CB-SD 3.63Å; W245-M270 HydrophobicContact CG-CE 4.5Å; W245-M270 HydrophobicContact CG-SD 4.19Å; W245-W393 HydrophobicContact CZ2-CH2 4.46Å; W245-W393 HydrophobicContact CZ2-CZ3 4.4Å; W245-M396 HydrophobicContact CH2-CE 3.16Å; W245-M396 HydrophobicContact CZ2-CE 3.58Å; W245-M396 HydrophobicContact CZ3-CE 3.81Å
246	D	86	Confident	85.5	Confident	11 Å²	11	19.4 Å²	19.4	6%	0.059	10%	0.098	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.2	-3.2	175.7	58.5	-28.4	0	0	0	113	Y93 G244 L248 N249 F250 Y392 M396	Y93-D246 HydrophobicContact CD1-CB 4.17Å; Y93-D246 HydrophobicContact CE1-CB 4.32Å; G244-D246 WeakPolarHBondContact CA-OD1 3.47Å; G244-D246 PolarHBondContact O-N 2.93Å; D246-L248 VanDerWaalsContact C-N 3.33Å; D246-L248 PolarHBondContact O-N 3.23Å; D246-N249 VanDerWaalsContact O-CB 3.25Å; D246-N249 WeakPolarHBondContact O-CB 3.44Å; D246-N249 PolarHBondContact O-N 3.42Å; D246-N249 VanDerWaalsContact O-N 3.1Å; D246-F250 WeakPolarHBondContact O-CD2 3.24Å; D246-Y392 PolarHBondContact OD1-OH 2.69Å; D246-Y392 PolarHBondContact OD2-OH 2.57Å; D246-M396 HydrophobicContact CB-CE 4.05Å
247	T	79.1	Confident	85.1	Confident	36 Å²	36	24.8 Å²	24.8	22%	0.221	13%	0.128	C	C	.	.	H	α-helix	trans	-63.2	-37.3	-177.5	-46	0	0	0	0	112.8	L48 N52 G244 W245 N249 F250	L48-T247 HydrophobicContact CD2-CG2 3.86Å; N52-T247 WeakPolarHBondContact ND2-CB 3.37Å; N52-T247 VanDerWaalsContact ND2-CG2 3.26Å; N52-T247 WeakPolarHBondContact ND2-CG2 3.49Å; N52-T247 PolarHBondContact ND2-OG1 3.47Å; N52-T247 VanDerWaalsContact ND2-OG1 3.15Å; G244-T247 WeakPolarHBondContact O-CB 3.26Å; G244-T247 PolarHBondContact O-N 2.98Å; G244-T247 VanDerWaalsContact O-N 3.1Å; G244-T247 PolarHBondContact O-OG1 3.3Å; W245-T247 PolarHBondContact O-N 3.41Å; T247-N249 PolarHBondContact O-N 3.21Å; T247-F250 WeakPolarHBondContact O-CB 3.47Å; T247-F250 PolarHBondContact O-N 3.06Å
248	L	78.1	Confident	84.6	Confident	0 Å²	0	25.9 Å²	25.9	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-63.4	-24.6	178.3	-75.3	-172	0	0	0	112.8	L48 I49 D246 F250 V251 T252 I255 L262	L48-L248 HydrophobicContact CB-CD2 4.21Å; L48-L248 HydrophobicContact CD1-CD2 4Å; L48-L248 HydrophobicContact CD2-CD2 3.83Å; L48-L248 HydrophobicContact CD2-CG 4.32Å; L48-L248 HydrophobicContact CG-CD2 4.24Å; I49-L248 HydrophobicContact CD1-CD1 3.36Å; I49-L248 HydrophobicContact CD1-CG 3.95Å; I49-L248 HydrophobicContact CG1-CD1 3.61Å; I49-L248 HydrophobicContact CG1-CG 3.69Å; D246-L248 VanDerWaalsContact C-N 3.33Å; D246-L248 PolarHBondContact O-N 3.23Å; L248-F250 PolarHBondContact O-N 2.97Å; L248-V251 HydrophobicContact CD2-CG2 4.14Å; L248-V251 CarbonylContact O-C 3.1Å; L248-V251 PolarHBondContact O-N 2.91Å; L248-T252 PolarHBondContact O-N 2.89Å; L248-T252 VanDerWaalsContact O-N 3.16Å; L248-T252 PolarHBondContact O-OG1 3.42Å; L248-I255 HydrophobicContact CB-CD1 4.23Å; L248-I255 HydrophobicContact CD2-CD1 4.25Å; L248-L262 HydrophobicContact CB-CD1 3.48Å; L248-L262 VanDerWaalsContact CB-CD1 3.48Å; L248-L262 HydrophobicContact CD1-CD1 4.04Å; L248-L262 HydrophobicContact CG-CD1 4.43Å
249	N	83.1	Confident	84.1	Confident	1 Å²	1	31.6 Å²	31.6	1%	0.005	16%	0.161	C	C	.	.	H	α-helix	trans	-67.2	-24.6	175.2	-70.8	81.7	0	0	0	112.6	Y93 A105 Y109 D246 T247 T252	Y93-N249 PolarHBondContact O-ND2 3.41Å; A105-N249 HydrophobicContact CB-CB 3.81Å; Y109-N249 HydrophobicContact CE2-CB 4.46Å; Y109-N249 WeakPolarHBondContact OH-CB 3.09Å; Y109-N249 PolarHBondContact OH-ND2 2.77Å; D246-N249 VanDerWaalsContact O-CB 3.25Å; D246-N249 WeakPolarHBondContact O-CB 3.44Å; D246-N249 PolarHBondContact O-N 3.42Å; D246-N249 VanDerWaalsContact O-N 3.1Å; T247-N249 PolarHBondContact O-N 3.21Å; N249-T252 VanDerWaalsContact CA-OG1 3.32Å; N249-T252 WeakPolarHBondContact CA-OG1 3.46Å; N249-T252 PolarHBondContact O-OG1 3.37Å
250	F	74.7	Confident	83.8	Confident	65 Å²	65	39.8 Å²	39.8	29%	0.285	19%	0.192	S	C	.	.	H	α-helix	trans	-76.8	-26.9	175.2	-69.5	-89.4	0	0	0	113.1	A105 D246 T247 L248	A105-F250 HydrophobicContact CB-CD1 3.71Å; A105-F250 HydrophobicContact CB-CD2 3.61Å; A105-F250 HydrophobicContact CB-CE1 3.63Å; A105-F250 HydrophobicContact CB-CE2 3.54Å; A105-F250 HydrophobicContact CB-CG 3.72Å; A105-F250 HydrophobicContact CB-CZ 3.56Å; D246-F250 WeakPolarHBondContact O-CD2 3.24Å; T247-F250 WeakPolarHBondContact O-CB 3.47Å; T247-F250 PolarHBondContact O-N 3.06Å; L248-F250 PolarHBondContact O-N 2.97Å
251	V	73.8	Confident	83.6	Confident	17 Å²	17	40.3 Å²	40.3	10%	0.103	20%	0.195	C	C	.	.	T	Hydrogen-bonded Turn	trans	-112.4	22.8	-176.8	-65.3	0	0	0	0	112.3	I40 L248 E253 E254 I255	I40-V251 HydrophobicContact CD1-CB 3.97Å; I40-V251 HydrophobicContact CD1-CG2 3.79Å; L248-V251 HydrophobicContact CD2-CG2 4.14Å; L248-V251 CarbonylContact O-C 3.1Å; L248-V251 PolarHBondContact O-N 2.91Å; V251-E253 PolarHBondContact O-N 3.41Å; V251-E254 WeakPolarHBondContact O-CB 3.24Å; V251-E254 PolarHBondContact O-N 2.65Å; V251-I255 PolarHBondContact O-N 3.33Å
252	T	76.8	Confident	83.4	Confident	6 Å²	6	40.3 Å²	40.3	4%	0.037	20%	0.195	C	C	.	.	G	3₁₀ helix	trans	-60.8	-30.9	-175.4	-60.8	0	0	0	0	112.8	L248 N249 E254 I255 P258 L262	L248-T252 PolarHBondContact O-N 2.89Å; L248-T252 VanDerWaalsContact O-N 3.16Å; L248-T252 PolarHBondContact O-OG1 3.42Å; N249-T252 VanDerWaalsContact CA-OG1 3.32Å; N249-T252 WeakPolarHBondContact CA-OG1 3.46Å; N249-T252 PolarHBondContact O-OG1 3.37Å; T252-E254 PolarHBondContact O-N 3.34Å; T252-I255 PolarHBondContact O-N 3.42Å; T252-P258 HydrophobicContact CG2-CB 3.92Å; T252-L262 HydrophobicContact CG2-CD2 4.49Å
253	E	76.6	Confident	83.2	Confident	70 Å²	70	41.2 Å²	41.2	33%	0.327	20%	0.201	S	C	.	.	G	3₁₀ helix	trans	-63.6	-26.7	175.1	-66.4	-177.6	-148.4	0	0	113.1	L36 K38 T101 S103 V251	L36-E253 HydrophobicContact CD1-CB 4.18Å; K38-E253 WeakPolarHBondContact CG-O 3.44Å; T101-E253 WeakPolarHBondContact O-CG 3.17Å; S103-E253 PolarHBondContact N-OE1 3.17Å; S103-E253 PolarHBondContact OG-OE1 3.34Å; V251-E253 PolarHBondContact O-N 3.41Å
254	E	81.3	Confident	83.4	Confident	57 Å²	57	43.3 Å²	43.3	27%	0.266	21%	0.21	S	C	.	.	G	3₁₀ helix	trans	-91.7	-7.2	-178.2	-60.2	175.2	-135.7	0	0	112.6	L36 K38 E39 I40 V251 T252	L36-E254 HydrophobicContact CB-CG 4.15Å; L36-E254 HydrophobicContact CD1-CG 4.23Å; K38-E254 CarbonylContact C-O 3.5Å; K38-E254 VanDerWaalsContact CA-O 3.29Å; K38-E254 WeakPolarHBondContact CA-O 3.46Å; E39-E254 PolarHBondContact N-O 3.12Å; I40-E254 HydrophobicContact CD1-CB 3.79Å; I40-E254 HydrophobicContact CG1-CB 4.14Å; I40-E254 PolarHBondContact N-O 3.21Å; V251-E254 WeakPolarHBondContact O-CB 3.24Å; V251-E254 PolarHBondContact O-N 2.65Å; T252-E254 PolarHBondContact O-N 3.34Å
255	I	83.5	Confident	83.8	Confident	3 Å²	3	42.8 Å²	42.8	2%	0.015	20%	0.204	C	C	.	.	B	Isolated β-bridge	trans	-79.4	131.5	-179.1	-62.4	175.1	0	0	0	111.1	I40 L248 V251 T252 N257 P258 N261 L262	I40-I255 HydrophobicContact CB-CG1 4.21Å; I40-I255 HydrophobicContact CG2-CG1 4.21Å; L248-I255 HydrophobicContact CB-CD1 4.23Å; L248-I255 HydrophobicContact CD2-CD1 4.25Å; V251-I255 PolarHBondContact O-N 3.33Å; T252-I255 PolarHBondContact O-N 3.42Å; I255-N257 PolarHBondContact O-N 2.7Å; I255-P258 HydrophobicContact CB-CB 4.36Å; I255-P258 HydrophobicContact CG2-CB 4.33Å; I255-N261 HydrophobicContact CG2-CB 3.96Å; I255-L262 HydrophobicContact CD1-CD1 4.1Å
256	K	85.3	Confident	83.9	Confident	97 Å²	97	42.8 Å²	42.8	42%	0.422	21%	0.205	S	C	.	.	S	Bend	trans	-68.2	126.1	168	-66.8	179.5	-180	175.8	0	108.8	K38 I40 N261	K38-K256 HydrophobicContact CB-CG 4.34Å; K38-K256 WeakPolarHBondContact O-CE 2.95Å; K38-K256 VanDerWaalsContact O-CG 3.24Å; K38-K256 WeakPolarHBondContact O-CG 3.46Å; I40-K256 WeakPolarHBondContact O-CB 3.13Å; I40-K256 PolarHBondContact O-N 2.98Å; K256-N261 WeakPolarHBondContact O-CB 3.49Å; K256-N261 PolarHBondContact O-ND2 3.16Å
257	N	86.4	Confident	84.1	Confident	115 Å²	115	45 Å²	45	62%	0.615	22%	0.224	S	C	*	.	S	Bend	trans	47.8	64.9	180	-61.5	-24.7	0	0	0	113.2	I255 E259 R260 N261	I255-N257 PolarHBondContact O-N 2.7Å; N257-E259 VanDerWaalsContact C-N 3.25Å; N257-E259 PolarHBondContact O-N 3.41Å; N257-R260 PolarHBondContact O-N 3.47Å; N257-R260 VanDerWaalsContact O-N 3.11Å; N257-N261 WeakPolarHBondContact O-CB 3.32Å; N257-N261 PolarHBondContact O-N 3.34Å
258	P	84.4	Confident	84.7	Confident	22 Å²	22	46.9 Å²	46.9	14%	0.143	23%	0.232	C	C	.	.	H	α-helix	trans	-58.1	-36.1	-171.7	23.5	-33.3	0	0	0	112.8	T252 I255 R260 L262 P263	T252-P258 HydrophobicContact CG2-CB 3.92Å; I255-P258 HydrophobicContact CB-CB 4.36Å; I255-P258 HydrophobicContact CG2-CB 4.33Å; P258-R260 PolarHBondContact O-N 3.41Å; P258-R260 VanDerWaalsContact O-N 3.16Å; P258-L262 WeakPolarHBondContact O-CB 3.01Å; P258-L262 PolarHBondContact O-N 3.03Å; P258-P263 WeakPolarHBondContact O-CD 3.26Å
259	E	86.2	Confident	85.3	Confident	121 Å²	121	46.9 Å²	46.9	57%	0.565	23%	0.232	S	C	*	.	H	α-helix	trans	-56	-34.1	179.1	-57.4	-178.9	176.7	0	0	113.6	N257 P263 P416	N257-E259 VanDerWaalsContact C-N 3.25Å; N257-E259 PolarHBondContact O-N 3.41Å; E259-P263 WeakPolarHBondContact O-CD 3.4Å; E259-P263 WeakPolarHBondContact O-CG 3.29Å; E259-P416 HydrophobicContact CB-CB 4.06Å; E259-P416 HydrophobicContact CG-CB 3.54Å; E259-P416 HydrophobicContact CG-CG 3.93Å; E259-P416 WeakPolarHBondContact OE1-CG 3.41Å
260	R	88.7	Confident	85.7	Confident	172 Å²	172	46.9 Å²	46.9	65%	0.649	23%	0.232	S	C	*	.	H	α-helix	trans	-99.5	-45.6	179.4	177.8	177.7	174.8	-167.3	-0.4	111.8	N257 P258 P263 L264	N257-R260 PolarHBondContact O-N 3.47Å; N257-R260 VanDerWaalsContact O-N 3.11Å; P258-R260 PolarHBondContact O-N 3.41Å; P258-R260 VanDerWaalsContact O-N 3.16Å; R260-P263 WeakPolarHBondContact O-CD 3.22Å; R260-L264 HydrophobicContact CG-CD1 3.59Å; R260-L264 HydrophobicContact CG-CG 4.47Å; R260-L264 WeakPolarHBondContact O-CB 3.48Å; R260-L264 WeakPolarHBondContact O-CD1 3.48Å; R260-L264 WeakPolarHBondContact O-CG 3.49Å; R260-L264 PolarHBondContact O-N 3.46Å
261	N	89.8	Confident	86.5	Confident	19 Å²	19	46.8 Å²	46.8	10%	0.102	24%	0.238	C	C	.	.	H	α-helix	trans	-78.9	-30.4	-169.5	-74.3	-5.5	0	0	0	112.8	L42 I255 K256 N257 S265	L42-N261 HydrophobicContact CD1-CB 4.3Å; I255-N261 HydrophobicContact CG2-CB 3.96Å; K256-N261 WeakPolarHBondContact O-CB 3.49Å; K256-N261 PolarHBondContact O-ND2 3.16Å; N257-N261 WeakPolarHBondContact O-CB 3.32Å; N257-N261 PolarHBondContact O-N 3.34Å; N261-S265 VanDerWaalsContact O-CB 3.27Å; N261-S265 WeakPolarHBondContact O-CB 3.46Å; N261-S265 PolarHBondContact O-N 3.38Å; N261-S265 PolarHBondContact O-OG 3.07Å
262	L	87.8	Confident	87.4	Confident	0 Å²	0	49.3 Å²	49.3	0%	0	25%	0.25	C	S	.	.	H	α-helix	trans	-65.8	-53	176.6	178.4	69.7	0	0	0	111.2	A94 T98 L248 T252 I255 P258 L264 S265 I266	A94-L262 HydrophobicContact CB-CG 4.48Å; T98-L262 HydrophobicContact CG2-CD2 4.29Å; L248-L262 HydrophobicContact CB-CD1 3.48Å; L248-L262 VanDerWaalsContact CB-CD1 3.48Å; L248-L262 HydrophobicContact CD1-CD1 4.04Å; L248-L262 HydrophobicContact CG-CD1 4.43Å; T252-L262 HydrophobicContact CG2-CD2 4.49Å; I255-L262 HydrophobicContact CD1-CD1 4.1Å; P258-L262 WeakPolarHBondContact O-CB 3.01Å; P258-L262 PolarHBondContact O-N 3.03Å; L262-L264 PolarHBondContact O-N 3.13Å; L262-S265 PolarHBondContact O-N 3.34Å; L262-I266 HydrophobicContact CD1-CD1 4.28Å; L262-I266 HydrophobicContact CG-CD1 4.37Å; L262-I266 PolarHBondContact O-N 2.65Å
263	P	89.4	Confident	88.2	Confident	19 Å²	19	49 Å²	49	12%	0.123	25%	0.248	C	C	.	.	H	α-helix	trans	-65.2	-38.5	179.5	-20.9	34.6	0	0	0	112.8	A94 P258 E259 R260 I266 A267 L417	A94-P263 HydrophobicContact CB-CB 4.47Å; A94-P263 HydrophobicContact CB-CG 4.3Å; P258-P263 WeakPolarHBondContact O-CD 3.26Å; E259-P263 WeakPolarHBondContact O-CD 3.4Å; E259-P263 WeakPolarHBondContact O-CG 3.29Å; R260-P263 WeakPolarHBondContact O-CD 3.22Å; P263-I266 PolarHBondContact O-N 2.69Å; P263-A267 WeakPolarHBondContact O-CB 3.46Å; P263-A267 PolarHBondContact O-N 3.12Å; P263-L417 HydrophobicContact CB-CD2 4.27Å; P263-L417 HydrophobicContact CG-CD1 4.26Å; P263-L417 HydrophobicContact CG-CD2 3.82Å
264	L	90.2	Very high	89	Confident	65 Å²	65	46.7 Å²	46.7	34%	0.34	24%	0.239	S	C	.	.	H	α-helix	trans	-66.3	-38.7	177.3	-73.2	175.8	0	0	0	112.3	L42 R260 L262 I266 A267 I268	L42-L264 HydrophobicContact CD1-CB 3.62Å; L42-L264 HydrophobicContact CD2-CD1 4.5Å; R260-L264 HydrophobicContact CG-CD1 3.59Å; R260-L264 HydrophobicContact CG-CG 4.47Å; R260-L264 WeakPolarHBondContact O-CB 3.48Å; R260-L264 WeakPolarHBondContact O-CD1 3.48Å; R260-L264 WeakPolarHBondContact O-CG 3.49Å; R260-L264 PolarHBondContact O-N 3.46Å; L262-L264 PolarHBondContact O-N 3.13Å; L264-I266 VanDerWaalsContact C-N 3.28Å; L264-I266 PolarHBondContact O-N 3.42Å; L264-A267 PolarHBondContact O-N 3.38Å; L264-I268 VanDerWaalsContact O-CG1 3.3Å; L264-I268 WeakPolarHBondContact O-CG1 3.49Å; L264-I268 PolarHBondContact O-N 2.99Å
265	S	91.2	Very high	89.7	Confident	2 Å²	2	48.8 Å²	48.8	1%	0.014	25%	0.251	C	S	.	.	H	α-helix	trans	-60	-43.5	176.4	-60.8	0	0	0	0	110.7	L42 N261 L262 S269	L42-S265 WeakPolarHBondContact CD1-OG 3.34Å; N261-S265 VanDerWaalsContact O-CB 3.27Å; N261-S265 WeakPolarHBondContact O-CB 3.46Å; N261-S265 PolarHBondContact O-N 3.38Å; N261-S265 PolarHBondContact O-OG 3.07Å; L262-S265 PolarHBondContact O-N 3.34Å; S265-S269 VanDerWaalsContact O-CB 3.23Å; S265-S269 WeakPolarHBondContact O-CB 3.18Å; S265-S269 PolarHBondContact O-N 3.49Å; S265-S269 PolarHBondContact O-OG 3.05Å
266	I	90.1	Very high	90.2	Very high	1 Å²	1	50 Å²	50	1%	0.005	26%	0.257	C	S	.	.	H	α-helix	trans	-66	-48.4	177	-70.4	165.9	0	0	0	111.2	I49 A90 A94 L262 P263 L264 I268 S269 M270	I49-I266 HydrophobicContact CD1-CB 4.48Å; I49-I266 HydrophobicContact CD1-CG1 3.66Å; A90-I266 HydrophobicContact CB-CD1 4.34Å; A90-I266 HydrophobicContact CB-CG1 4.43Å; A90-I266 HydrophobicContact CB-CG2 3.41Å; A90-I266 VanDerWaalsContact CB-CG2 3.41Å; A94-I266 HydrophobicContact CB-CD1 3.81Å; L262-I266 HydrophobicContact CD1-CD1 4.28Å; L262-I266 HydrophobicContact CG-CD1 4.37Å; L262-I266 PolarHBondContact O-N 2.65Å; P263-I266 PolarHBondContact O-N 2.69Å; L264-I266 VanDerWaalsContact C-N 3.28Å; L264-I266 PolarHBondContact O-N 3.42Å; I266-I268 PolarHBondContact O-N 3.01Å; I266-S269 PolarHBondContact O-N 3.2Å; I266-S269 PolarHBondContact O-OG 3.44Å; I266-M270 HydrophobicContact CG2-CG 3.87Å; I266-M270 WeakPolarHBondContact O-CB 3.2Å; I266-M270 VanDerWaalsContact O-CG 3.24Å; I266-M270 WeakPolarHBondContact O-CG 3.4Å; I266-M270 PolarHBondContact O-N 2.89Å
267	A	89.1	Confident	90.7	Very high	56 Å²	56	45.4 Å²	45.4	46%	0.463	24%	0.237	S	C	.	.	H	α-helix	trans	-61.2	-30.7	-178.1	0	0	0	0	0	113.2	P263 L264 P271	P263-A267 WeakPolarHBondContact O-CB 3.46Å; P263-A267 PolarHBondContact O-N 3.12Å; L264-A267 PolarHBondContact O-N 3.38Å; A267-P271 WeakPolarHBondContact O-CD 3.35Å; A267-P271 WeakPolarHBondContact O-CG 3.37Å
268	I	91.6	Very high	91.1	Very high	77 Å²	77	42.2 Å²	42.2	40%	0.395	22%	0.219	S	C	.	.	H	α-helix	trans	-84.3	-47.4	177	-64.9	167.3	0	0	0	111.2	V46 L264 I266 I272	V46-I268 HydrophobicContact CG1-CG2 4.05Å; V46-I268 HydrophobicContact CG2-CB 4.11Å; V46-I268 HydrophobicContact CG2-CD1 4.35Å; V46-I268 HydrophobicContact CG2-CG2 4.12Å; L264-I268 VanDerWaalsContact O-CG1 3.3Å; L264-I268 WeakPolarHBondContact O-CG1 3.49Å; L264-I268 PolarHBondContact O-N 2.99Å; I266-I268 PolarHBondContact O-N 3.01Å; I268-I272 HydrophobicContact CG2-CD1 3.76Å; I268-I272 VanDerWaalsContact O-CD1 3.28Å; I268-I272 WeakPolarHBondContact O-CD1 3.42Å; I268-I272 VanDerWaalsContact O-CG1 3.25Å; I268-I272 WeakPolarHBondContact O-CG1 3.25Å
269	S	91.6	Very high	91.7	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-69.5	-41.6	-173.3	54	0	0	0	0	113.2	I49 S265 I266 I272 V273	I49-S269 WeakPolarHBondContact CD1-OG 3.21Å; I49-S269 VanDerWaalsContact CG2-OG 3.23Å; I49-S269 WeakPolarHBondContact CG2-OG 3.35Å; S265-S269 VanDerWaalsContact O-CB 3.23Å; S265-S269 WeakPolarHBondContact O-CB 3.18Å; S265-S269 PolarHBondContact O-N 3.49Å; S265-S269 PolarHBondContact O-OG 3.05Å; I266-S269 PolarHBondContact O-N 3.2Å; I266-S269 PolarHBondContact O-OG 3.44Å; S269-I272 PolarHBondContact O-N 3.43Å; S269-V273 WeakPolarHBondContact O-CG2 3.37Å; S269-V273 PolarHBondContact O-N 3.45Å
270	M	91.8	Very high	92.2	Very high	1 Å²	1	38.5 Å²	38.5	1%	0.005	20%	0.202	C	C	.	.	H	α-helix	trans	-63.2	-46.1	-173.4	-64.7	-60.1	-58.1	0	0	113.7	M53 V87 A90 W245 I266 I272 T274	M53-M270 HydrophobicContact CE-CE 3.6Å; M53-M270 HydrophobicContact CE-SD 3.6Å; M53-M270 HydrophobicContact SD-CE 4.36Å; M53-M270 HydrophobicContact SD-SD 3.54Å; V87-M270 HydrophobicContact CG2-CB 3.56Å; V87-M270 HydrophobicContact CG2-CE 4.31Å; V87-M270 HydrophobicContact CG2-CG 4.27Å; A90-M270 HydrophobicContact CB-CG 4.34Å; A90-M270 HydrophobicContact CB-SD 4.37Å; W245-M270 HydrophobicContact CB-SD 3.63Å; W245-M270 HydrophobicContact CG-CE 4.5Å; W245-M270 HydrophobicContact CG-SD 4.19Å; I266-M270 HydrophobicContact CG2-CG 3.87Å; I266-M270 WeakPolarHBondContact O-CB 3.2Å; I266-M270 VanDerWaalsContact O-CG 3.24Å; I266-M270 WeakPolarHBondContact O-CG 3.4Å; I266-M270 PolarHBondContact O-N 2.89Å; M270-I272 PolarHBondContact O-N 3.37Å; M270-T274 WeakPolarHBondContact O-CB 3.46Å; M270-T274 PolarHBondContact O-N 3.24Å; M270-T274 PolarHBondContact O-OG1 3.37Å
271	P	92	Very high	92.5	Very high	62 Å²	62	30.3 Å²	30.3	40%	0.403	17%	0.171	S	C	.	.	H	α-helix	trans	-63.4	-39.4	174.2	-23.7	35.7	0	0	0	112.8	A267 T274 I275	A267-P271 WeakPolarHBondContact O-CD 3.35Å; A267-P271 WeakPolarHBondContact O-CG 3.37Å; P271-T274 PolarHBondContact O-N 3.46Å; P271-I275 WeakPolarHBondContact O-CB 3.42Å; P271-I275 VanDerWaalsContact O-CG1 3.27Å; P271-I275 WeakPolarHBondContact O-CG1 3.21Å; P271-I275 PolarHBondContact O-N 2.89Å
272	I	91.7	Very high	92.8	Very high	71 Å²	71	30.9 Å²	30.9	36%	0.364	18%	0.175	S	C	.	.	H	α-helix	trans	-58.9	-51.2	178.4	-69.1	170.5	0	0	0	110.2	I268 S269 M270 T274 I275 I276	I268-I272 HydrophobicContact CG2-CD1 3.76Å; I268-I272 VanDerWaalsContact O-CD1 3.28Å; I268-I272 WeakPolarHBondContact O-CD1 3.42Å; I268-I272 VanDerWaalsContact O-CG1 3.25Å; I268-I272 WeakPolarHBondContact O-CG1 3.25Å; S269-I272 PolarHBondContact O-N 3.43Å; M270-I272 PolarHBondContact O-N 3.37Å; I272-T274 VanDerWaalsContact C-N 3.32Å; I272-T274 PolarHBondContact O-N 3.14Å; I272-I275 PolarHBondContact O-N 3.43Å; I272-I276 HydrophobicContact CG2-CD1 3.74Å; I272-I276 VanDerWaalsContact O-CG1 3.27Å; I272-I276 WeakPolarHBondContact O-CG1 3.37Å; I272-I276 PolarHBondContact O-N 3.31Å
273	V	93.3	Very high	93.2	Very high	0 Å²	0	31 Å²	31	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-62.7	-41.8	179.5	176.9	0	0	0	0	110.8	V50 M53 I54 Y242 S269 I275 I276 Y277	V50-V273 HydrophobicContact CG1-CG2 4.44Å; V50-V273 HydrophobicContact CG2-CG2 4.21Å; M53-V273 HydrophobicContact CB-CG1 4.22Å; M53-V273 HydrophobicContact CB-CG2 4.27Å; M53-V273 HydrophobicContact CE-CB 4.26Å; M53-V273 HydrophobicContact CE-CG1 3.88Å; M53-V273 HydrophobicContact SD-CB 4.47Å; M53-V273 HydrophobicContact SD-CG1 4.46Å; M53-V273 HydrophobicContact SD-CG2 4.11Å; I54-V273 HydrophobicContact CD1-CG2 4.35Å; I54-V273 HydrophobicContact CG1-CG1 4.3Å; I54-V273 HydrophobicContact CG1-CG2 4.1Å; Y242-V273 HydrophobicContact CD1-CG1 4.24Å; Y242-V273 HydrophobicContact CE1-CG1 4.18Å; S269-V273 WeakPolarHBondContact O-CG2 3.37Å; S269-V273 PolarHBondContact O-N 3.45Å; V273-I275 PolarHBondContact O-N 2.6Å; V273-I276 PolarHBondContact O-N 2.71Å; V273-Y277 HydrophobicContact CG1-CD1 4.24Å; V273-Y277 HydrophobicContact CG1-CD2 3.91Å; V273-Y277 HydrophobicContact CG1-CE1 3.89Å; V273-Y277 HydrophobicContact CG1-CE2 3.51Å; V273-Y277 HydrophobicContact CG1-CG 4.27Å; V273-Y277 WeakPolarHBondContact O-CB 3.45Å; V273-Y277 PolarHBondContact O-N 2.88Å
274	T	94.3	Very high	93.5	Very high	21 Å²	21	30.1 Å²	30.1	13%	0.129	17%	0.17	C	C	.	.	H	α-helix	trans	-61.7	-45.9	179	-56.1	0	0	0	0	112	M270 P271 I272 Y277 I278	M270-T274 WeakPolarHBondContact O-CB 3.46Å; M270-T274 PolarHBondContact O-N 3.24Å; M270-T274 PolarHBondContact O-OG1 3.37Å; P271-T274 PolarHBondContact O-N 3.46Å; I272-T274 VanDerWaalsContact C-N 3.32Å; I272-T274 PolarHBondContact O-N 3.14Å; T274-Y277 PolarHBondContact O-N 2.89Å; T274-I278 HydrophobicContact CG2-CD1 3.97Å; T274-I278 WeakPolarHBondContact O-CG1 3.44Å; T274-I278 PolarHBondContact O-N 3.02Å
275	I	94.6	Very high	93.7	Very high	100 Å²	100	27 Å²	27	51%	0.513	15%	0.154	S	C	.	.	H	α-helix	trans	-62.5	-46.6	176.9	-69.7	165.8	0	0	0	110.3	P271 I272 V273 Y277 I278 L279	P271-I275 WeakPolarHBondContact O-CB 3.42Å; P271-I275 VanDerWaalsContact O-CG1 3.27Å; P271-I275 WeakPolarHBondContact O-CG1 3.21Å; P271-I275 PolarHBondContact O-N 2.89Å; I272-I275 PolarHBondContact O-N 3.43Å; V273-I275 PolarHBondContact O-N 2.6Å; I275-Y277 VanDerWaalsContact C-N 3.35Å; I275-Y277 PolarHBondContact O-N 2.87Å; I275-I278 PolarHBondContact O-N 3.5Å; I275-L279 HydrophobicContact CG2-CD1 3.65Å; I275-L279 HydrophobicContact CG2-CG 4.18Å; I275-L279 WeakPolarHBondContact O-CB 3.25Å; I275-L279 VanDerWaalsContact O-CG 3.23Å; I275-L279 WeakPolarHBondContact O-CG 3.28Å; I275-L279 PolarHBondContact O-N 3.19Å
276	I	94.3	Very high	93.8	Very high	30 Å²	30	27.1 Å²	27.1	15%	0.154	16%	0.155	C	C	.	.	H	α-helix	trans	-57.9	-48.5	178.4	-71.3	169.6	0	0	0	110.3	I54 L198 I202 I272 V273 I278 L279 T280	I54-I276 HydrophobicContact CD1-CD1 3.89Å; I54-I276 HydrophobicContact CD1-CG2 4.46Å; L198-I276 HydrophobicContact CB-CG2 4.32Å; L198-I276 HydrophobicContact CD1-CG2 3.8Å; I202-I276 HydrophobicContact CD1-CG2 4.16Å; I272-I276 HydrophobicContact CG2-CD1 3.74Å; I272-I276 VanDerWaalsContact O-CG1 3.27Å; I272-I276 WeakPolarHBondContact O-CG1 3.37Å; I272-I276 PolarHBondContact O-N 3.31Å; V273-I276 PolarHBondContact O-N 2.71Å; I276-I278 PolarHBondContact O-N 3.5Å; I276-L279 PolarHBondContact O-N 2.97Å; I276-T280 WeakPolarHBondContact O-CB 3.42Å; I276-T280 PolarHBondContact O-N 3.1Å; I276-T280 PolarHBondContact O-OG1 2.96Å
277	Y	95.5	Very high	93.9	Very high	0 Å²	0	28.2 Å²	28.2	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-64.6	-43	-178.5	-71.2	-3	0	0	0	113.1	M53 I54 I58 W79 S241 Y242 V273 T274 I275 T280 N281	M53-Y277 VanDerWaalsContact C-OH 3.27Å; M53-Y277 PolarHBondContact O-OH 3.44Å; I54-Y277 WeakPolarHBondContact CA-OH 3.41Å; I54-Y277 HydrophobicContact CG1-CE1 4.13Å; I58-Y277 HydrophobicContact CB-CD1 4.1Å; I58-Y277 HydrophobicContact CB-CE1 3.74Å; I58-Y277 HydrophobicContact CD1-CD1 3.61Å; I58-Y277 HydrophobicContact CD1-CD2 4.44Å; I58-Y277 HydrophobicContact CD1-CE1 4.14Å; I58-Y277 HydrophobicContact CD1-CG 3.77Å; I58-Y277 HydrophobicContact CG1-CD1 3.69Å; I58-Y277 HydrophobicContact CG1-CE1 3.86Å; I58-Y277 HydrophobicContact CG1-CG 4.37Å; I58-Y277 HydrophobicContact CG2-CE1 4.28Å; W79-Y277 AromaticContact CE3-CD2 3.96Å; W79-Y277 HydrophobicContact CE3-CD2 3.96Å; W79-Y277 HydrophobicContact CE3-CG 4.31Å; W79-Y277 HydrophobicContact CH2-CD2 4.49Å; W79-Y277 AromaticContact CZ3-CD2 3.45Å; W79-Y277 HydrophobicContact CZ3-CD2 3.45Å; W79-Y277 VanDerWaalsContact CZ3-CD2 3.45Å; W79-Y277 HydrophobicContact CZ3-CE2 4.13Å; W79-Y277 AromaticContact CZ3-CG 3.92Å; W79-Y277 HydrophobicContact CZ3-CG 3.92Å; S241-Y277 VanDerWaalsContact O-CE2 3.25Å; S241-Y277 WeakPolarHBondContact O-CE2 3.28Å; S241-Y277 PolarHBondContact O-OH 3.21Å; Y242-Y277 AromaticContact CD1-CD2 3.92Å; Y242-Y277 HydrophobicContact CD1-CD2 3.92Å; Y242-Y277 AromaticContact CD1-CE2 3.87Å; Y242-Y277 HydrophobicContact CD1-CE2 3.87Å; Y242-Y277 HydrophobicContact CD2-CD2 4.44Å; Y242-Y277 AromaticContact CE1-CD2 3.44Å; Y242-Y277 HydrophobicContact CE1-CD2 3.44Å; Y242-Y277 VanDerWaalsContact CE1-CD2 3.44Å; Y242-Y277 AromaticContact CE1-CE2 3.88Å; Y242-Y277 HydrophobicContact CE1-CE2 3.88Å; Y242-Y277 HydrophobicContact CE1-CG 4.43Å; Y242-Y277 HydrophobicContact CE2-CD2 4.02Å; Y242-Y277 HydrophobicContact CG-CD2 4.39Å; Y242-Y277 HydrophobicContact CG-CE2 4.24Å; Y242-Y277 AromaticContact CZ-CD2 3.49Å; Y242-Y277 VanDerWaalsContact CZ-CD2 3.49Å; V273-Y277 HydrophobicContact CG1-CD1 4.24Å; V273-Y277 HydrophobicContact CG1-CD2 3.91Å; V273-Y277 HydrophobicContact CG1-CE1 3.89Å; V273-Y277 HydrophobicContact CG1-CE2 3.51Å; V273-Y277 HydrophobicContact CG1-CG 4.27Å; V273-Y277 WeakPolarHBondContact O-CB 3.45Å; V273-Y277 PolarHBondContact O-N 2.88Å; T274-Y277 PolarHBondContact O-N 2.89Å; I275-Y277 VanDerWaalsContact C-N 3.35Å; I275-Y277 PolarHBondContact O-N 2.87Å; Y277-T280 PolarHBondContact O-N 3.16Å; Y277-N281 PolarHBondContact O-N 3.36Å; Y277-N281 PolarHBondContact O-ND2 3.05Å
278	I	96.1	Very high	94.1	Very high	47 Å²	47	25.7 Å²	25.7	24%	0.241	14%	0.14	C	C	.	.	H	α-helix	trans	-62	-47.8	175.7	-68.6	171.8	0	0	0	109.9	W79 A80 T274 I275 I276 T280 N281 V282	W79-I278 HydrophobicContact CB-CG1 4.33Å; A80-I278 HydrophobicContact CB-CD1 3.97Å; T274-I278 HydrophobicContact CG2-CD1 3.97Å; T274-I278 WeakPolarHBondContact O-CG1 3.44Å; T274-I278 PolarHBondContact O-N 3.02Å; I275-I278 PolarHBondContact O-N 3.5Å; I276-I278 PolarHBondContact O-N 3.5Å; I278-T280 VanDerWaalsContact C-N 3.33Å; I278-T280 PolarHBondContact O-N 3.43Å; I278-N281 PolarHBondContact O-N 3.17Å; I278-V282 HydrophobicContact CG2-CG2 4.38Å; I278-V282 WeakPolarHBondContact O-CG2 3.42Å; I278-V282 PolarHBondContact O-N 3.21Å
279	L	96.5	Very high	94.1	Very high	66 Å²	66	26.2 Å²	26.2	35%	0.346	14%	0.144	S	C	.	.	H	α-helix	trans	-64	-36.7	179.9	-70	178.2	0	0	0	112.5	I202 I275 I276 V282 A283	I202-L279 HydrophobicContact CD1-CB 3.96Å; I202-L279 HydrophobicContact CG1-CB 3.92Å; I202-L279 HydrophobicContact CG2-CB 4.01Å; I202-L279 HydrophobicContact CG2-CD1 4.15Å; I275-L279 HydrophobicContact CG2-CD1 3.65Å; I275-L279 HydrophobicContact CG2-CG 4.18Å; I275-L279 WeakPolarHBondContact O-CB 3.25Å; I275-L279 VanDerWaalsContact O-CG 3.23Å; I275-L279 WeakPolarHBondContact O-CG 3.28Å; I275-L279 PolarHBondContact O-N 3.19Å; I276-L279 PolarHBondContact O-N 2.97Å; L279-V282 PolarHBondContact O-N 2.78Å; L279-A283 WeakPolarHBondContact O-CB 3.37Å; L279-A283 PolarHBondContact O-N 3.15Å
280	T	95.8	Very high	93.9	Very high	0 Å²	0	27 Å²	27	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-64.2	-43.5	174.6	-63	0	0	0	0	111.4	I58 L198 I201 I276 Y277 I278 A283 Y284	I58-T280 HydrophobicContact CD1-CG2 4.42Å; I58-T280 HydrophobicContact CG1-CG2 4.11Å; L198-T280 HydrophobicContact CD2-CG2 4.06Å; I201-T280 HydrophobicContact CG2-CG2 4.22Å; I276-T280 WeakPolarHBondContact O-CB 3.42Å; I276-T280 PolarHBondContact O-N 3.1Å; I276-T280 PolarHBondContact O-OG1 2.96Å; Y277-T280 PolarHBondContact O-N 3.16Å; I278-T280 VanDerWaalsContact C-N 3.33Å; I278-T280 PolarHBondContact O-N 3.43Å; T280-A283 WeakPolarHBondContact O-CB 3.41Å; T280-A283 PolarHBondContact O-N 3.1Å; T280-Y284 HydrophobicContact CG2-CD2 4.19Å; T280-Y284 HydrophobicContact CG2-CE1 4.39Å; T280-Y284 HydrophobicContact CG2-CE2 3.56Å; T280-Y284 PolarHBondContact O-N 3.18Å
281	N	96.4	Very high	93.8	Very high	0 Å²	0	31.2 Å²	31.2	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-67.1	-40.4	176.2	-77.5	-83.3	0	0	0	111.9	P62 L76 W79 Y277 I278 A283 Y284 Y285	P62-N281 WeakPolarHBondContact CB-OD1 3.29Å; L76-N281 HydrophobicContact CD2-CB 3.75Å; W79-N281 WeakPolarHBondContact CZ2-ND2 3.26Å; W79-N281 PolarHBondContact NE1-ND2 3.02Å; W79-N281 PolarHBondContact NE1-OD1 3.19Å; Y277-N281 PolarHBondContact O-N 3.36Å; Y277-N281 PolarHBondContact O-ND2 3.05Å; I278-N281 PolarHBondContact O-N 3.17Å; N281-A283 VanDerWaalsContact C-N 3.28Å; N281-A283 PolarHBondContact O-N 3.2Å; N281-Y284 PolarHBondContact O-N 3.2Å; N281-Y285 HydrophobicContact CB-CE2 4.09Å; N281-Y285 VanDerWaalsContact O-CD2 3.3Å; N281-Y285 WeakPolarHBondContact O-CD2 3.4Å; N281-Y285 VanDerWaalsContact O-CG 3.23Å; N281-Y285 PolarHBondContact O-N 3.23Å
282	V	96	Very high	93.7	Very high	31 Å²	31	29.9 Å²	29.9	19%	0.188	18%	0.176	C	C	.	.	H	α-helix	trans	-58.1	-42.6	172.2	169.1	0	0	0	0	110.8	L76 L209 F217 I278 L279 Y285 A286	L76-V282 HydrophobicContact CD1-CG2 3.94Å; L76-V282 HydrophobicContact CD2-CG2 3.86Å; L209-V282 HydrophobicContact CD1-CG1 3.79Å; F217-V282 HydrophobicContact CZ-CG1 4.16Å; I278-V282 HydrophobicContact CG2-CG2 4.38Å; I278-V282 WeakPolarHBondContact O-CG2 3.42Å; I278-V282 PolarHBondContact O-N 3.21Å; L279-V282 PolarHBondContact O-N 2.78Å; V282-Y285 PolarHBondContact O-N 2.99Å; V282-A286 WeakPolarHBondContact O-CB 3.27Å; V282-A286 PolarHBondContact O-N 2.71Å
283	A	96	Very high	93.8	Very high	2 Å²	2	26.5 Å²	26.5	2%	0.017	16%	0.158	C	C	.	.	H	α-helix	trans	-61.8	-44.9	175.7	0	0	0	0	0	111.9	I201 L279 T280 N281 A286 F303	I201-A283 HydrophobicContact CG2-CB 3.95Å; I201-A283 WeakPolarHBondContact O-CB 3.47Å; L279-A283 WeakPolarHBondContact O-CB 3.37Å; L279-A283 PolarHBondContact O-N 3.15Å; T280-A283 WeakPolarHBondContact O-CB 3.41Å; T280-A283 PolarHBondContact O-N 3.1Å; N281-A283 VanDerWaalsContact C-N 3.28Å; N281-A283 PolarHBondContact O-N 3.2Å; A283-A286 PolarHBondContact O-N 3.02Å; A283-F303 HydrophobicContact CB-CE2 4.42Å; A283-F303 WeakPolarHBondContact O-CE2 3.11Å
284	Y	95.2	Very high	93.7	Very high	0 Å²	0	29.9 Å²	29.9	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-59.7	-47.8	175.6	-66.3	-30	0	0	0	112.1	P62 I201 T280 N281 A286 V287 L288 V299 A300 F303	P62-Y284 HydrophobicContact CB-CD2 4.25Å; P62-Y284 HydrophobicContact CB-CE2 4.49Å; P62-Y284 HydrophobicContact CG-CD2 4.16Å; P62-Y284 HydrophobicContact CG-CE2 3.97Å; I201-Y284 HydrophobicContact CD1-CE1 4.3Å; I201-Y284 HydrophobicContact CG2-CD1 4.21Å; I201-Y284 HydrophobicContact CG2-CE1 3.71Å; T280-Y284 HydrophobicContact CG2-CD2 4.19Å; T280-Y284 HydrophobicContact CG2-CE1 4.39Å; T280-Y284 HydrophobicContact CG2-CE2 3.56Å; T280-Y284 PolarHBondContact O-N 3.18Å; N281-Y284 PolarHBondContact O-N 3.2Å; Y284-A286 VanDerWaalsContact C-N 3.29Å; Y284-A286 PolarHBondContact O-N 2.9Å; Y284-V287 PolarHBondContact O-N 3.5Å; Y284-L288 WeakPolarHBondContact O-CB 3.41Å; Y284-L288 PolarHBondContact O-N 3.05Å; Y284-V299 HydrophobicContact CD1-CG1 4.29Å; Y284-V299 HydrophobicContact CD2-CG1 3.98Å; Y284-V299 HydrophobicContact CE2-CG1 4.19Å; Y284-V299 HydrophobicContact CG-CG1 4.04Å; Y284-A300 HydrophobicContact CE1-CB 4.21Å; Y284-A300 WeakPolarHBondContact OH-CB 3.34Å; Y284-F303 HydrophobicContact CD1-CB 3.9Å; Y284-F303 AromaticContact CD1-CD2 3.77Å; Y284-F303 HydrophobicContact CD1-CD2 3.77Å; Y284-F303 HydrophobicContact CD1-CE2 4.49Å; Y284-F303 AromaticContact CD1-CG 3.89Å; Y284-F303 HydrophobicContact CD1-CG 3.89Å; Y284-F303 HydrophobicContact CE1-CB 3.94Å; Y284-F303 HydrophobicContact CE1-CD2 4.37Å; Y284-F303 HydrophobicContact CE1-CG 4.04Å
285	Y	94.7	Very high	93.4	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-70.3	-23.8	-178.2	-56.9	-26.4	0	0	0	113.6	L66 Y72 S75 L76 N216 N281 V282 V287 I293	L66-Y285 HydrophobicContact CD2-CE1 4.37Å; Y72-Y285 AromaticContact CD1-CD1 3.67Å; Y72-Y285 HydrophobicContact CD1-CD1 3.67Å; Y72-Y285 HydrophobicContact CD1-CD2 4.15Å; Y72-Y285 AromaticContact CD1-CE1 3.92Å; Y72-Y285 HydrophobicContact CD1-CE1 3.92Å; Y72-Y285 HydrophobicContact CD1-CE2 4.35Å; Y72-Y285 AromaticContact CD1-CG 3.82Å; Y72-Y285 HydrophobicContact CD1-CG 3.82Å; Y72-Y285 AromaticContact CE1-CD1 4Å; Y72-Y285 HydrophobicContact CE1-CD1 4Å; Y72-Y285 HydrophobicContact CE1-CE1 4.38Å; Y72-Y285 HydrophobicContact CE1-CG 4.43Å; Y72-Y285 HydrophobicContact CG-CD1 4.4Å; Y72-Y285 HydrophobicContact CG-CD2 4.2Å; Y72-Y285 HydrophobicContact CG-CG 4.08Å; S75-Y285 WeakPolarHBondContact CB-OH 3.23Å; S75-Y285 PolarHBondContact OG-OH 2.62Å; L76-Y285 HydrophobicContact CD1-CD2 4.46Å; L76-Y285 HydrophobicContact CD2-CD2 4.23Å; L76-Y285 HydrophobicContact CD2-CE2 3.97Å; L76-Y285 HydrophobicContact CG-CD2 4.25Å; L76-Y285 HydrophobicContact CG-CE2 4.03Å; N216-Y285 VanDerWaalsContact CB-O 3.28Å; N216-Y285 WeakPolarHBondContact CB-O 3.16Å; N216-Y285 PolarHBondContact ND2-O 3.18Å; N281-Y285 HydrophobicContact CB-CE2 4.09Å; N281-Y285 VanDerWaalsContact O-CD2 3.3Å; N281-Y285 WeakPolarHBondContact O-CD2 3.4Å; N281-Y285 VanDerWaalsContact O-CG 3.23Å; N281-Y285 PolarHBondContact O-N 3.23Å; V282-Y285 PolarHBondContact O-N 2.99Å; Y285-V287 VanDerWaalsContact C-N 3.27Å; Y285-V287 PolarHBondContact O-N 3.33Å; Y285-I293 HydrophobicContact CD1-CD1 3.46Å; Y285-I293 VanDerWaalsContact CD1-CD1 3.46Å; Y285-I293 HydrophobicContact CE1-CD1 3.59Å
286	A	93.6	Very high	93.2	Very high	4 Å²	4	27.6 Å²	27.6	3%	0.033	17%	0.173	C	C	.	.	H	α-helix	trans	-69.6	-24	173.8	0	0	0	0	0	113.5	L209 F217 V282 A283 Y284	L209-A286 HydrophobicContact CD1-CB 4.48Å; L209-A286 HydrophobicContact CD2-CB 3.71Å; L209-A286 HydrophobicContact CG-CB 3.79Å; F217-A286 HydrophobicContact CE2-CB 3.94Å; F217-A286 HydrophobicContact CZ-CB 4.42Å; V282-A286 WeakPolarHBondContact O-CB 3.27Å; V282-A286 PolarHBondContact O-N 2.71Å; A283-A286 PolarHBondContact O-N 3.02Å; Y284-A286 VanDerWaalsContact C-N 3.29Å; Y284-A286 PolarHBondContact O-N 2.9Å
287	V	92.2	Very high	92.7	Very high	25 Å²	25	29.4 Å²	29.4	15%	0.152	18%	0.184	C	C	.	.	H	α-helix	trans	-114.6	-37.9	-171.8	172.5	0	0	0	0	112.4	K208 Y284 Y285 F303 H306 T307	K208-V287 HydrophobicContact CB-CG2 4.06Å; K208-V287 HydrophobicContact CG-CG2 3.85Å; Y284-V287 PolarHBondContact O-N 3.5Å; Y285-V287 VanDerWaalsContact C-N 3.27Å; Y285-V287 PolarHBondContact O-N 3.33Å; V287-F303 HydrophobicContact CB-CD2 3.8Å; V287-F303 HydrophobicContact CB-CE2 3.69Å; V287-F303 HydrophobicContact CG1-CD2 3.96Å; V287-F303 HydrophobicContact CG1-CE2 4.13Å; V287-F303 HydrophobicContact CG2-CD2 4.1Å; V287-F303 HydrophobicContact CG2-CE2 3.45Å; V287-F303 VanDerWaalsContact CG2-CE2 3.45Å; V287-F303 HydrophobicContact CG2-CZ 4.25Å; V287-H306 HydrophobicContact CG1-CB 3.91Å; V287-T307 HydrophobicContact CB-CG2 4.31Å; V287-T307 HydrophobicContact CG1-CG2 3.46Å; V287-T307 VanDerWaalsContact CG1-CG2 3.46Å; V287-T307 HydrophobicContact CG2-CG2 3.89Å
288	L	92.5	Very high	92.4	Very high	2 Å²	2	29.4 Å²	29.4	1%	0.01	18%	0.184	C	C	.	.	S	Bend	trans	-108.8	136.7	-173.3	-58.7	178.4	0	0	0	110.8	N216 Y284 I293 V299 T302 F303 H306	N216-L288 PolarHBondContact ND2-O 2.97Å; Y284-L288 WeakPolarHBondContact O-CB 3.41Å; Y284-L288 PolarHBondContact O-N 3.05Å; L288-I293 HydrophobicContact CB-CD1 4.04Å; L288-I293 HydrophobicContact CB-CG1 3.69Å; L288-I293 HydrophobicContact CD1-CG1 4.07Å; L288-V299 HydrophobicContact CD1-CG1 4.03Å; L288-T302 HydrophobicContact CD1-CG2 4.35Å; L288-T302 HydrophobicContact CD2-CG2 3.96Å; L288-F303 HydrophobicContact CD1-CB 4.06Å; L288-H306 HydrophobicContact CD2-CB 4.45Å
289	D	91.4	Very high	92.2	Very high	89 Å²	89	27.3 Å²	27.3	48%	0.476	17%	0.173	S	C	.	.			trans	-77.6	159.4	170.1	-61	-23.4	0	0	0	110.9	N216 S291 A292 I293	N216-D289 PolarHBondContact ND2-OD1 2.93Å; N216-D289 PolarHBondContact OD1-OD1 3.41Å; D289-S291 VanDerWaalsContact C-N 3.3Å; D289-S291 PolarHBondContact O-N 3.46Å; D289-A292 WeakPolarHBondContact O-CA 3.23Å; D289-A292 WeakPolarHBondContact O-CB 3.33Å; D289-A292 PolarHBondContact O-N 2.99Å; D289-I293 PolarHBondContact O-N 2.97Å
290	G	87.8	Confident	92	Very high	16 Å²	16	24.1 Å²	24.1	17%	0.165	16%	0.156	C	C	.	.	H	α-helix	trans	-63	-39.5	-170.6	0	0	0	0	0	111.6	Y72 A292 I293 L294	Y72-G290 VanDerWaalsContact OH-CA 3.31Å; Y72-G290 WeakPolarHBondContact OH-CA 3.28Å; Y72-G290 PolarHBondContact OH-N 3.16Å; G290-A292 VanDerWaalsContact C-N 3.3Å; G290-A292 PolarHBondContact O-N 3.49Å; G290-I293 PolarHBondContact O-N 2.87Å; G290-L294 WeakPolarHBondContact O-CB 3.3Å; G290-L294 WeakPolarHBondContact O-CG 3.49Å; G290-L294 PolarHBondContact O-N 3.29Å
291	S	89.8	Confident	91.8	Very high	90 Å²	90	24.2 Å²	24.2	63%	0.629	16%	0.157	S	C	*	.	H	α-helix	trans	-60.3	-38.4	173.1	52.2	0	0	0	0	112.6	D289 L294 A295	D289-S291 VanDerWaalsContact C-N 3.3Å; D289-S291 PolarHBondContact O-N 3.46Å; S291-L294 PolarHBondContact O-N 2.98Å; S291-A295 VanDerWaalsContact O-CB 3.26Å; S291-A295 WeakPolarHBondContact O-CB 3.29Å; S291-A295 PolarHBondContact O-N 3.24Å
292	A	90.7	Very high	91.5	Very high	33 Å²	33	25.4 Å²	25.4	27%	0.273	16%	0.164	S	C	.	.	H	α-helix	trans	-68.4	-38.7	178.5	0	0	0	0	0	111.7	D289 G290 S296	D289-A292 WeakPolarHBondContact O-CA 3.23Å; D289-A292 WeakPolarHBondContact O-CB 3.33Å; D289-A292 PolarHBondContact O-N 2.99Å; G290-A292 VanDerWaalsContact C-N 3.3Å; G290-A292 PolarHBondContact O-N 3.49Å; A292-S296 VanDerWaalsContact O-CB 3.31Å; A292-S296 WeakPolarHBondContact O-CB 3.25Å; A292-S296 PolarHBondContact O-N 3.49Å
293	I	92.3	Very high	91.4	Very high	0 Å²	0	24 Å²	24	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-67.8	-43.1	175.3	-62.7	174.9	0	0	0	110.7	L66 Y285 L288 D289 G290 S296 V299	L66-I293 HydrophobicContact CD2-CB 3.92Å; L66-I293 HydrophobicContact CD2-CD1 4.13Å; L66-I293 HydrophobicContact CD2-CG2 3.78Å; Y285-I293 HydrophobicContact CD1-CD1 3.46Å; Y285-I293 VanDerWaalsContact CD1-CD1 3.46Å; Y285-I293 HydrophobicContact CE1-CD1 3.59Å; L288-I293 HydrophobicContact CB-CD1 4.04Å; L288-I293 HydrophobicContact CB-CG1 3.69Å; L288-I293 HydrophobicContact CD1-CG1 4.07Å; D289-I293 PolarHBondContact O-N 2.97Å; G290-I293 PolarHBondContact O-N 2.87Å; I293-S296 PolarHBondContact O-N 3.38Å; I293-V299 HydrophobicContact CG1-CG1 4.42Å; I293-V299 HydrophobicContact CG2-CG1 4.29Å; I293-V299 HydrophobicContact CG2-CG2 4.13Å
294	L	91.6	Very high	91.2	Very high	72 Å²	72	23.9 Å²	23.9	38%	0.377	15%	0.154	S	C	.	.	H	α-helix	trans	-69.7	-33.8	-178.7	-67.1	174.1	0	0	0	112.5	K63 L66 I67 G290 S291	K63-L294 WeakPolarHBondContact CE-O 3.48Å; K63-L294 PolarHBondContact NZ-O 3.03Å; K63-L294 VanDerWaalsContact NZ-O 3.1Å; L66-L294 HydrophobicContact CB-CD2 4.38Å; L66-L294 HydrophobicContact CD2-CD2 4.42Å; L66-L294 HydrophobicContact CD2-CG 4.37Å; L66-L294 HydrophobicContact CG-CD2 4.34Å; I67-L294 HydrophobicContact CB-CD2 4.31Å; I67-L294 HydrophobicContact CD1-CD2 4.46Å; I67-L294 HydrophobicContact CG1-CD2 3.38Å; G290-L294 WeakPolarHBondContact O-CB 3.3Å; G290-L294 WeakPolarHBondContact O-CG 3.49Å; G290-L294 PolarHBondContact O-N 3.29Å; S291-L294 PolarHBondContact O-N 2.98Å
295	A	89.4	Confident	90.9	Very high	63 Å²	63	27.1 Å²	27.1	52%	0.521	17%	0.172	S	C	.	.	H	α-helix	trans	-77.1	-21.6	176.1	0	0	0	0	0	113.3	S291	S291-A295 VanDerWaalsContact O-CB 3.26Å; S291-A295 WeakPolarHBondContact O-CB 3.29Å; S291-A295 PolarHBondContact O-N 3.24Å
296	S	88.5	Confident	90.7	Very high	9 Å²	9	33.1 Å²	33.1	6%	0.063	20%	0.2	C	C	.	.			trans	-88.4	128.2	-174.7	-177.5	0	0	0	0	113	K63 A292 I293 A298 V299 T302	K63-S296 WeakPolarHBondContact CD-O 3.31Å; K63-S296 PolarHBondContact NZ-O 3.4Å; A292-S296 VanDerWaalsContact O-CB 3.31Å; A292-S296 WeakPolarHBondContact O-CB 3.25Å; A292-S296 PolarHBondContact O-N 3.49Å; I293-S296 PolarHBondContact O-N 3.38Å; S296-A298 VanDerWaalsContact C-N 3.3Å; S296-A298 PolarHBondContact OG-N 2.9Å; S296-A298 PolarHBondContact OG-O 2.78Å; S296-V299 PolarHBondContact OG-N 3.49Å; S296-T302 WeakPolarHBondContact CB-OG1 3.47Å; S296-T302 PolarHBondContact OG-OG1 3.1Å
297	D	84.6	Confident	90.5	Very high	69 Å²	69	34.4 Å²	34.4	37%	0.369	21%	0.207	S	C	.	.	S	Bend	trans	-83.8	-7.3	169.4	-72.2	-23.9	0	0	0	113.5	K63	K63-D297 IonicContact NZ-OD1 2.69Å; K63-D297 PolarHBondContact NZ-OD1 3.45Å
298	A	89.9	Confident	90.2	Very high	0 Å²	0	35 Å²	35	0%	0	21%	0.209	C	C	.	.	S	Bend	trans	-140.5	72.5	178.5	0	0	0	0	0	110.3	Y145 Q148 S296 A300 V301 T302	Y145-A298 HydrophobicContact CD1-CB 4.18Å; Y145-A298 HydrophobicContact CD2-CB 3.95Å; Y145-A298 HydrophobicContact CE1-CB 3.99Å; Y145-A298 HydrophobicContact CE2-CB 3.76Å; Y145-A298 HydrophobicContact CG-CB 4.18Å; Q148-A298 HydrophobicContact CB-CB 4.17Å; Q148-A298 HydrophobicContact CG-CB 4.16Å; S296-A298 VanDerWaalsContact C-N 3.3Å; S296-A298 PolarHBondContact OG-N 2.9Å; S296-A298 PolarHBondContact OG-O 2.78Å; A298-A300 PolarHBondContact O-N 2.98Å; A298-V301 HydrophobicContact CB-CB 4.11Å; A298-V301 HydrophobicContact CB-CG2 3.88Å; A298-V301 WeakPolarHBondContact O-CB 3.04Å; A298-V301 PolarHBondContact O-N 2.61Å; A298-T302 PolarHBondContact O-N 3.04Å
299	V	91.7	Very high	90	Very high	2 Å²	2	37.1 Å²	37.1	1%	0.012	23%	0.232	C	C	.	.	H	α-helix	trans	-51.9	-38.2	-171.7	-178.8	0	0	0	0	112.6	K63 Y145 Y284 L288 I293 S296 V301 T302 F303	K63-V299 HydrophobicContact CB-CG2 4.3Å; Y145-V299 PolarHBondContact OH-N 3.32Å; Y284-V299 HydrophobicContact CD1-CG1 4.29Å; Y284-V299 HydrophobicContact CD2-CG1 3.98Å; Y284-V299 HydrophobicContact CE2-CG1 4.19Å; Y284-V299 HydrophobicContact CG-CG1 4.04Å; L288-V299 HydrophobicContact CD1-CG1 4.03Å; I293-V299 HydrophobicContact CG1-CG1 4.42Å; I293-V299 HydrophobicContact CG2-CG1 4.29Å; I293-V299 HydrophobicContact CG2-CG2 4.13Å; S296-V299 PolarHBondContact OG-N 3.49Å; V299-V301 PolarHBondContact O-N 3.45Å; V299-T302 PolarHBondContact O-N 3.17Å; V299-F303 WeakPolarHBondContact O-CB 3.24Å; V299-F303 PolarHBondContact O-N 3.03Å
300	A	91.9	Very high	89.6	Confident	0 Å²	0	39.1 Å²	39.1	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-71	-29.7	-180	0	0	0	0	0	113.3	F59 Y145 I201 Y284 A298 A304 I315	F59-A300 HydrophobicContact CD1-CB 3.89Å; F59-A300 HydrophobicContact CE1-CB 4.23Å; Y145-A300 HydrophobicContact CE1-CB 3.86Å; Y145-A300 PolarHBondContact OH-N 2.85Å; I201-A300 HydrophobicContact CD1-CB 4.08Å; Y284-A300 HydrophobicContact CE1-CB 4.21Å; Y284-A300 WeakPolarHBondContact OH-CB 3.34Å; A298-A300 PolarHBondContact O-N 2.98Å; A300-A304 WeakPolarHBondContact O-CB 3.4Å; A300-A304 PolarHBondContact O-N 2.92Å; A300-I315 HydrophobicContact CB-CG2 3.75Å; A300-I315 WeakPolarHBondContact O-CG2 3.35Å
301	V	90.8	Very high	89.4	Confident	2 Å²	2	43.6 Å²	43.6	1%	0.012	27%	0.265	C	S	.	.	H	α-helix	trans	-69.2	-47.4	173.9	-179.7	0	0	0	0	109.2	Y145 Q148 P149 A298 V299 F303 A304 D305 P316	Y145-V301 HydrophobicContact CD1-CG2 3.56Å; Y145-V301 HydrophobicContact CE1-CG2 3.75Å; Y145-V301 HydrophobicContact CG-CG2 4.48Å; Q148-V301 HydrophobicContact CG-CB 4.4Å; Q148-V301 HydrophobicContact CG-CG1 4.09Å; P149-V301 HydrophobicContact CG-CG1 4.39Å; A298-V301 HydrophobicContact CB-CB 4.11Å; A298-V301 HydrophobicContact CB-CG2 3.88Å; A298-V301 WeakPolarHBondContact O-CB 3.04Å; A298-V301 PolarHBondContact O-N 2.61Å; V299-V301 PolarHBondContact O-N 3.45Å; V301-F303 VanDerWaalsContact C-N 3.29Å; V301-F303 PolarHBondContact O-N 3.29Å; V301-A304 WeakPolarHBondContact O-CA 3.41Å; V301-A304 WeakPolarHBondContact O-CB 3.43Å; V301-A304 PolarHBondContact O-N 3.44Å; V301-D305 PolarHBondContact O-N 3.05Å; V301-P316 HydrophobicContact CG2-CB 3.84Å; V301-P316 HydrophobicContact CG2-CG 4.43Å
302	T	91	Very high	89.1	Confident	24 Å²	24	42 Å²	42	15%	0.147	25%	0.249	C	C	.	.	H	α-helix	trans	-58.4	-41.3	175.6	-50.7	0	0	0	0	111.9	L288 S296 A298 V299 A304 D305 H306	L288-T302 HydrophobicContact CD1-CG2 4.35Å; L288-T302 HydrophobicContact CD2-CG2 3.96Å; S296-T302 WeakPolarHBondContact CB-OG1 3.47Å; S296-T302 PolarHBondContact OG-OG1 3.1Å; A298-T302 PolarHBondContact O-N 3.04Å; V299-T302 PolarHBondContact O-N 3.17Å; T302-A304 VanDerWaalsContact C-N 3.34Å; T302-A304 PolarHBondContact O-N 3.23Å; T302-D305 PolarHBondContact O-N 3.13Å; T302-H306 PolarHBondContact O-CD2 3.31Å; T302-H306 VanDerWaalsContact O-CD2 3.3Å; T302-H306 PolarHBondContact O-N 3.46Å
303	F	93.2	Very high	88.8	Confident	1 Å²	1	47.4 Å²	47.4	0%	0.004	26%	0.263	C	S	.	.	H	α-helix	trans	-59.6	-44.7	172.6	175.7	-89.1	0	0	0	112.1	I201 T204 A283 Y284 V287 L288 V299 V301 H306 T307	I201-F303 HydrophobicContact CB-CE1 4.24Å; I201-F303 HydrophobicContact CG1-CD1 4.21Å; I201-F303 HydrophobicContact CG1-CE1 4.19Å; I201-F303 HydrophobicContact CG2-CD1 4.24Å; I201-F303 HydrophobicContact CG2-CE1 3.96Å; I201-F303 HydrophobicContact CG2-CZ 4.16Å; T204-F303 HydrophobicContact CG2-CE1 4.06Å; T204-F303 HydrophobicContact CG2-CZ 3.87Å; A283-F303 HydrophobicContact CB-CE2 4.42Å; A283-F303 WeakPolarHBondContact O-CE2 3.11Å; Y284-F303 HydrophobicContact CD1-CB 3.9Å; Y284-F303 AromaticContact CD1-CD2 3.77Å; Y284-F303 HydrophobicContact CD1-CD2 3.77Å; Y284-F303 HydrophobicContact CD1-CE2 4.49Å; Y284-F303 AromaticContact CD1-CG 3.89Å; Y284-F303 HydrophobicContact CD1-CG 3.89Å; Y284-F303 HydrophobicContact CE1-CB 3.94Å; Y284-F303 HydrophobicContact CE1-CD2 4.37Å; Y284-F303 HydrophobicContact CE1-CG 4.04Å; V287-F303 HydrophobicContact CB-CD2 3.8Å; V287-F303 HydrophobicContact CB-CE2 3.69Å; V287-F303 HydrophobicContact CG1-CD2 3.96Å; V287-F303 HydrophobicContact CG1-CE2 4.13Å; V287-F303 HydrophobicContact CG2-CD2 4.1Å; V287-F303 HydrophobicContact CG2-CE2 3.45Å; V287-F303 VanDerWaalsContact CG2-CE2 3.45Å; V287-F303 HydrophobicContact CG2-CZ 4.25Å; L288-F303 HydrophobicContact CD1-CB 4.06Å; V299-F303 WeakPolarHBondContact O-CB 3.24Å; V299-F303 PolarHBondContact O-N 3.03Å; V301-F303 VanDerWaalsContact C-N 3.29Å; V301-F303 PolarHBondContact O-N 3.29Å; F303-H306 PolarHBondContact O-N 3Å; F303-T307 HydrophobicContact CE1-CG2 4.41Å; F303-T307 HydrophobicContact CE2-CG2 4.3Å; F303-T307 HydrophobicContact CZ-CG2 4.2Å; F303-T307 WeakPolarHBondContact O-CB 3.39Å; F303-T307 WeakPolarHBondContact O-CG2 3.27Å; F303-T307 PolarHBondContact O-N 2.91Å; F303-T307 PolarHBondContact O-OG1 3.42Å
304	A	91.6	Very high	88.6	Confident	0 Å²	0	50.1 Å²	50.1	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-64.2	-40.9	-179.7	0	0	0	0	0	111.9	A300 V301 T302 H306 T307 L308 N312 I315	A300-A304 WeakPolarHBondContact O-CB 3.4Å; A300-A304 PolarHBondContact O-N 2.92Å; V301-A304 WeakPolarHBondContact O-CA 3.41Å; V301-A304 WeakPolarHBondContact O-CB 3.43Å; V301-A304 PolarHBondContact O-N 3.44Å; T302-A304 VanDerWaalsContact C-N 3.34Å; T302-A304 PolarHBondContact O-N 3.23Å; A304-H306 VanDerWaalsContact C-N 3.3Å; A304-H306 PolarHBondContact O-N 3.48Å; A304-T307 PolarHBondContact O-N 2.94Å; A304-T307 VanDerWaalsContact O-N 3.17Å; A304-L308 HydrophobicContact CB-CD1 4.08Å; A304-L308 PolarHBondContact O-N 3.25Å; A304-N312 HydrophobicContact CB-CB 4.24Å; A304-I315 HydrophobicContact CB-CB 3.89Å; A304-I315 HydrophobicContact CB-CG1 3.73Å; A304-I315 HydrophobicContact CB-CG2 4.41Å
305	D	90.1	Very high	88.5	Confident	69 Å²	69	46.7 Å²	46.7	37%	0.369	26%	0.259	S	S	.	.	H	α-helix	trans	-63.1	-36.6	178.4	-69.6	-30.4	0	0	0	112.2	V301 T302 T307 N312	V301-D305 PolarHBondContact O-N 3.05Å; T302-D305 PolarHBondContact O-N 3.13Å; D305-T307 VanDerWaalsContact C-N 3.34Å; D305-T307 PolarHBondContact O-N 3.16Å; D305-N312 PolarHBondContact OD1-ND2 3.39Å
306	H	89.2	Confident	88.5	Confident	126 Å²	126	44 Å²	44	58%	0.583	24%	0.236	S	C	*	.	H	α-helix	trans	-76.6	-14.8	176.7	-83.6	-106.3	0	0	0	114.4	V287 L288 T302 F303 A304	V287-H306 HydrophobicContact CG1-CB 3.91Å; L288-H306 HydrophobicContact CD2-CB 4.45Å; T302-H306 PolarHBondContact O-CD2 3.31Å; T302-H306 VanDerWaalsContact O-CD2 3.3Å; T302-H306 PolarHBondContact O-N 3.46Å; F303-H306 PolarHBondContact O-N 3Å; A304-H306 VanDerWaalsContact C-N 3.3Å; A304-H306 PolarHBondContact O-N 3.48Å
307	T	91.2	Very high	88.5	Confident	31 Å²	31	47.6 Å²	47.6	19%	0.19	25%	0.254	C	S	.	.	H	α-helix	trans	-129.8	-42.1	-166.3	57.9	0	0	0	0	115.8	T204 V287 F303 A304 D305	T204-T307 HydrophobicContact CG2-CG2 4Å; V287-T307 HydrophobicContact CB-CG2 4.31Å; V287-T307 HydrophobicContact CG1-CG2 3.46Å; V287-T307 VanDerWaalsContact CG1-CG2 3.46Å; V287-T307 HydrophobicContact CG2-CG2 3.89Å; F303-T307 HydrophobicContact CE1-CG2 4.41Å; F303-T307 HydrophobicContact CE2-CG2 4.3Å; F303-T307 HydrophobicContact CZ-CG2 4.2Å; F303-T307 WeakPolarHBondContact O-CB 3.39Å; F303-T307 WeakPolarHBondContact O-CG2 3.27Å; F303-T307 PolarHBondContact O-N 2.91Å; F303-T307 PolarHBondContact O-OG1 3.42Å; A304-T307 PolarHBondContact O-N 2.94Å; A304-T307 VanDerWaalsContact O-N 3.17Å; D305-T307 VanDerWaalsContact C-N 3.34Å; D305-T307 PolarHBondContact O-N 3.16Å
308	L	86	Confident	88.6	Confident	36 Å²	36	45 Å²	45	19%	0.188	24%	0.241	C	C	.	.	T	Hydrogen-bonded Turn	trans	-93.3	-7.1	-167.6	-62.6	-176.9	0	0	0	113.5	V200 T204 A304 V310 M311 I315	V200-L308 HydrophobicContact CG1-CD1 4.16Å; V200-L308 HydrophobicContact CG1-CD2 4.27Å; T204-L308 HydrophobicContact CG2-CD2 4.31Å; A304-L308 HydrophobicContact CB-CD1 4.08Å; A304-L308 PolarHBondContact O-N 3.25Å; L308-V310 PolarHBondContact O-N 3.45Å; L308-V310 VanDerWaalsContact O-N 3.13Å; L308-M311 HydrophobicContact CB-CB 4.22Å; L308-M311 PolarHBondContact O-N 2.9Å; L308-I315 HydrophobicContact CD1-CD1 4.22Å; L308-I315 HydrophobicContact CD1-CG1 3.68Å
309	G	86.6	Confident	88.6	Confident	47 Å²	47	45 Å²	45	49%	0.485	24%	0.241	S	C	.	.	G	3₁₀ helix	trans	53.2	-118.4	179	0	0	0	0	0	111.4	M311 N312	G309-M311 PolarHBondContact O-N 3.41Å; G309-M311 VanDerWaalsContact O-N 3.15Å; G309-N312 WeakPolarHBondContact O-CB 3.38Å; G309-N312 VanDerWaalsContact O-CG 3.27Å; G309-N312 PolarHBondContact O-N 3.26Å; G309-N312 VanDerWaalsContact O-N 3.13Å; G309-N312 PolarHBondContact O-OD1 2.84Å
310	V	83.8	Confident	88.5	Confident	131 Å²	131	45.1 Å²	45.1	79%	0.794	24%	0.242	S	C	*	.	G	3₁₀ helix	trans	-63.2	-20.3	-179.2	-174.1	0	0	0	0	113.2	L308 W313	L308-V310 PolarHBondContact O-N 3.45Å; L308-V310 VanDerWaalsContact O-N 3.13Å; V310-W313 PolarHBondContact O-NE1 2.91Å
311	M	83	Confident	88.2	Confident	111 Å²	111	48 Å²	48	55%	0.547	26%	0.258	S	S	.	.	G	3₁₀ helix	trans	-92.2	7.9	179.5	-65.6	179.4	68.6	0	0	113.3	L308 G309 W313 I314	L308-M311 HydrophobicContact CB-CB 4.22Å; L308-M311 PolarHBondContact O-N 2.9Å; G309-M311 PolarHBondContact O-N 3.41Å; G309-M311 VanDerWaalsContact O-N 3.15Å; M311-W313 PolarHBondContact O-N 3.38Å; M311-I314 HydrophobicContact CB-CD1 4.01Å; M311-I314 HydrophobicContact CE-CD1 3.46Å; M311-I314 VanDerWaalsContact CE-CD1 3.46Å; M311-I314 HydrophobicContact CG-CD1 4.33Å; M311-I314 WeakPolarHBondContact O-CB 3.48Å; M311-I314 PolarHBondContact O-N 3.06Å
312	N	84.2	Confident	88	Confident	55 Å²	55	48 Å²	48	29%	0.294	26%	0.258	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.6	-33.6	-178.3	66.4	-12.6	0	0	0	113.5	A304 D305 G309 I314 I315 P316	A304-N312 HydrophobicContact CB-CB 4.24Å; D305-N312 PolarHBondContact OD1-ND2 3.39Å; G309-N312 WeakPolarHBondContact O-CB 3.38Å; G309-N312 VanDerWaalsContact O-CG 3.27Å; G309-N312 PolarHBondContact O-N 3.26Å; G309-N312 VanDerWaalsContact O-N 3.13Å; G309-N312 PolarHBondContact O-OD1 2.84Å; N312-I314 PolarHBondContact O-N 3.42Å; N312-I314 VanDerWaalsContact O-N 3.15Å; N312-I315 PolarHBondContact O-N 3.21Å; N312-P316 WeakPolarHBondContact O-CD 3.31Å
313	W	84.9	Confident	87.9	Confident	148 Å²	148	46.9 Å²	46.9	56%	0.561	25%	0.251	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.3	-18	-179.6	65.5	-93.1	0	0	0	114.7	V310 M311 P316 I317	V310-W313 PolarHBondContact O-NE1 2.91Å; M311-W313 PolarHBondContact O-N 3.38Å; W313-P316 WeakPolarHBondContact O-CD 3.35Å; W313-P316 WeakPolarHBondContact O-CG 3.49Å; W313-I317 HydrophobicContact CE3-CD1 3.71Å; W313-I317 HydrophobicContact CZ3-CD1 4.1Å; W313-I317 WeakPolarHBondContact O-CG1 3.46Å
314	I	87.3	Confident	87.7	Confident	57 Å²	57	49 Å²	49	29%	0.292	26%	0.259	S	S	.	.	H	α-helix	trans	-66.7	-41.8	-179.6	-64.1	177.3	0	0	0	110.9	M311 N312 A318	M311-I314 HydrophobicContact CB-CD1 4.01Å; M311-I314 HydrophobicContact CE-CD1 3.46Å; M311-I314 VanDerWaalsContact CE-CD1 3.46Å; M311-I314 HydrophobicContact CG-CD1 4.33Å; M311-I314 WeakPolarHBondContact O-CB 3.48Å; M311-I314 PolarHBondContact O-N 3.06Å; N312-I314 PolarHBondContact O-N 3.42Å; N312-I314 VanDerWaalsContact O-N 3.15Å; I314-A318 VanDerWaalsContact O-CB 3.28Å; I314-A318 WeakPolarHBondContact O-CB 3.46Å; I314-A318 PolarHBondContact O-N 3.47Å
315	I	89.3	Confident	87.3	Confident	0 Å²	0	49.3 Å²	49.3	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-64.9	-53.7	-176.4	-61.2	-60	0	0	0	112.8	A197 V200 I201 A300 A304 L308 N312 I317 A318 V319	A197-I315 HydrophobicContact CB-CD1 4.42Å; V200-I315 HydrophobicContact CG1-CD1 4.47Å; I201-I315 HydrophobicContact CD1-CD1 4.29Å; I201-I315 HydrophobicContact CG1-CD1 4.06Å; A300-I315 HydrophobicContact CB-CG2 3.75Å; A300-I315 WeakPolarHBondContact O-CG2 3.35Å; A304-I315 HydrophobicContact CB-CB 3.89Å; A304-I315 HydrophobicContact CB-CG1 3.73Å; A304-I315 HydrophobicContact CB-CG2 4.41Å; L308-I315 HydrophobicContact CD1-CD1 4.22Å; L308-I315 HydrophobicContact CD1-CG1 3.68Å; N312-I315 PolarHBondContact O-N 3.21Å; I315-I317 VanDerWaalsContact C-N 3.3Å; I315-I317 PolarHBondContact O-N 3.48Å; I315-A318 PolarHBondContact O-N 2.83Å; I315-V319 HydrophobicContact CG2-CG2 4.18Å; I315-V319 VanDerWaalsContact O-CG2 3.3Å; I315-V319 WeakPolarHBondContact O-CG2 3.36Å; I315-V319 PolarHBondContact O-N 3.11Å
316	P	89.6	Confident	87	Confident	7 Å²	7	47 Å²	47	5%	0.045	26%	0.255	C	S	.	.	H	α-helix	trans	-59	-40.6	179.7	19.7	-29.8	0	0	0	112.5	Y145 P149 V301 N312 W313 V319 A320	Y145-P316 WeakPolarHBondContact O-CB 3.39Å; P149-P316 HydrophobicContact CG-CB 3.51Å; P149-P316 HydrophobicContact CG-CG 3.64Å; V301-P316 HydrophobicContact CG2-CB 3.84Å; V301-P316 HydrophobicContact CG2-CG 4.43Å; N312-P316 WeakPolarHBondContact O-CD 3.31Å; W313-P316 WeakPolarHBondContact O-CD 3.35Å; W313-P316 WeakPolarHBondContact O-CG 3.49Å; P316-V319 PolarHBondContact O-N 3.29Å; P316-A320 VanDerWaalsContact O-CB 3.23Å; P316-A320 WeakPolarHBondContact O-CB 3.29Å; P316-A320 PolarHBondContact O-N 3.05Å
317	I	88.3	Confident	87	Confident	84 Å²	84	41 Å²	41	43%	0.431	23%	0.228	S	C	.	.	H	α-helix	trans	-64.7	-47.7	176.8	-63.9	-176.3	0	0	0	110.8	W313 I315 V319 A320 L321	W313-I317 HydrophobicContact CE3-CD1 3.71Å; W313-I317 HydrophobicContact CZ3-CD1 4.1Å; W313-I317 WeakPolarHBondContact O-CG1 3.46Å; I315-I317 VanDerWaalsContact C-N 3.3Å; I315-I317 PolarHBondContact O-N 3.48Å; I317-V319 VanDerWaalsContact C-N 3.33Å; I317-V319 PolarHBondContact O-N 2.92Å; I317-A320 PolarHBondContact O-N 2.81Å; I317-L321 HydrophobicContact CG2-CD1 3.95Å; I317-L321 HydrophobicContact CG2-CG 4.31Å; I317-L321 WeakPolarHBondContact O-CB 3.46Å; I317-L321 VanDerWaalsContact O-CG 3.26Å; I317-L321 WeakPolarHBondContact O-CG 3.4Å; I317-L321 PolarHBondContact O-N 2.99Å
318	A	88.2	Confident	86.8	Confident	13 Å²	13	39.8 Å²	39.8	11%	0.107	22%	0.22	C	C	.	.	H	α-helix	trans	-62.8	-39.8	-179.6	0	0	0	0	0	112.3	A197 I314 I315 S322	A197-A318 HydrophobicContact CB-CB 3.64Å; I314-A318 VanDerWaalsContact O-CB 3.28Å; I314-A318 WeakPolarHBondContact O-CB 3.46Å; I314-A318 PolarHBondContact O-N 3.47Å; I315-A318 PolarHBondContact O-N 2.83Å; A318-S322 WeakPolarHBondContact O-CB 3.27Å; A318-S322 PolarHBondContact O-N 3.29Å
319	V	88.6	Confident	86.5	Confident	0 Å²	0	39 Å²	39	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-69.1	-42.7	176.4	178	0	0	0	0	111.5	F59 Y145 I315 P316 I317 L321 S322 C323	F59-V319 HydrophobicContact CB-CG1 4.06Å; F59-V319 HydrophobicContact CD1-CG1 4.19Å; F59-V319 HydrophobicContact CD1-CG2 3.74Å; F59-V319 HydrophobicContact CD2-CB 4.41Å; F59-V319 HydrophobicContact CD2-CG1 3.53Å; F59-V319 HydrophobicContact CD2-CG2 4.13Å; F59-V319 HydrophobicContact CE1-CG2 3.51Å; F59-V319 HydrophobicContact CE2-CB 4.43Å; F59-V319 HydrophobicContact CE2-CG1 3.99Å; F59-V319 HydrophobicContact CE2-CG2 3.92Å; F59-V319 HydrophobicContact CG-CG1 3.64Å; F59-V319 HydrophobicContact CG-CG2 4.05Å; F59-V319 HydrophobicContact CZ-CG2 3.61Å; Y145-V319 HydrophobicContact CD1-CB 3.49Å; Y145-V319 VanDerWaalsContact CD1-CB 3.49Å; Y145-V319 HydrophobicContact CD1-CG1 3.34Å; Y145-V319 HydrophobicContact CD1-CG2 3.96Å; Y145-V319 HydrophobicContact CD2-CG1 3.9Å; Y145-V319 HydrophobicContact CE1-CB 3.89Å; Y145-V319 HydrophobicContact CE1-CG1 3.6Å; Y145-V319 HydrophobicContact CE1-CG2 3.88Å; Y145-V319 HydrophobicContact CE2-CG1 4.13Å; Y145-V319 HydrophobicContact CG-CB 4.02Å; Y145-V319 HydrophobicContact CG-CG1 3.49Å; Y145-V319 VanDerWaalsContact CG-CG1 3.49Å; I315-V319 HydrophobicContact CG2-CG2 4.18Å; I315-V319 VanDerWaalsContact O-CG2 3.3Å; I315-V319 WeakPolarHBondContact O-CG2 3.36Å; I315-V319 PolarHBondContact O-N 3.11Å; P316-V319 PolarHBondContact O-N 3.29Å; I317-V319 VanDerWaalsContact C-N 3.33Å; I317-V319 PolarHBondContact O-N 2.92Å; V319-L321 PolarHBondContact O-N 3.46Å; V319-S322 VanDerWaalsContact O-CB 3.27Å; V319-S322 WeakPolarHBondContact O-CB 3.36Å; V319-S322 PolarHBondContact O-N 3.45Å; V319-S322 VanDerWaalsContact O-N 3.16Å; V319-C323 PolarHBondContact O-N 2.98Å; V319-C323 PolarHBondContact O-SG 2.95Å
320	A	89.5	Confident	86.5	Confident	5 Å²	5	37.6 Å²	37.6	4%	0.041	20%	0.201	C	C	.	.	H	α-helix	trans	-60.4	-45.3	175.7	0	0	0	0	0	111.1	F142 P316 I317 S322 C323 Y324	F142-A320 HydrophobicContact CD2-CB 3.97Å; F142-A320 VanDerWaalsContact CD2-O 3.28Å; F142-A320 WeakPolarHBondContact CD2-O 3.36Å; F142-A320 HydrophobicContact CE2-CB 4Å; P316-A320 VanDerWaalsContact O-CB 3.23Å; P316-A320 WeakPolarHBondContact O-CB 3.29Å; P316-A320 PolarHBondContact O-N 3.05Å; I317-A320 PolarHBondContact O-N 2.81Å; A320-S322 VanDerWaalsContact C-N 3.3Å; A320-S322 PolarHBondContact O-N 2.74Å; A320-C323 PolarHBondContact O-N 2.93Å; A320-Y324 WeakPolarHBondContact O-CB 3.48Å; A320-Y324 PolarHBondContact O-N 3.44Å
321	L	86.2	Confident	86.7	Confident	62 Å²	62	31.3 Å²	31.3	33%	0.325	16%	0.163	S	C	.	.	H	α-helix	trans	-62.2	-37.1	175.1	-67.1	176.8	0	0	0	112.3	F190 I317 V319 Y324 G325	F190-L321 HydrophobicContact CD1-CB 4.02Å; F190-L321 HydrophobicContact CD1-CD1 4.31Å; F190-L321 HydrophobicContact CD1-CD2 4.41Å; F190-L321 HydrophobicContact CD1-CG 4.48Å; F190-L321 HydrophobicContact CE1-CB 4.25Å; F190-L321 HydrophobicContact CE1-CD1 4.09Å; F190-L321 HydrophobicContact CE1-CD2 3.78Å; F190-L321 HydrophobicContact CE1-CG 4.26Å; F190-L321 HydrophobicContact CE2-CD2 4.29Å; F190-L321 HydrophobicContact CG-CB 4.23Å; F190-L321 HydrophobicContact CZ-CD2 3.72Å; I317-L321 HydrophobicContact CG2-CD1 3.95Å; I317-L321 HydrophobicContact CG2-CG 4.31Å; I317-L321 WeakPolarHBondContact O-CB 3.46Å; I317-L321 VanDerWaalsContact O-CG 3.26Å; I317-L321 WeakPolarHBondContact O-CG 3.4Å; I317-L321 PolarHBondContact O-N 2.99Å; V319-L321 PolarHBondContact O-N 3.46Å; L321-Y324 PolarHBondContact O-N 2.92Å; L321-G325 PolarHBondContact O-N 3.19Å
322	S	86.6	Confident	86.7	Confident	2 Å²	2	27 Å²	27	1%	0.014	14%	0.142	C	C	.	.	H	α-helix	trans	-60.2	-49.4	173.2	-174.5	0	0	0	0	111.8	K194 A318 V319 A320 Y324 G325 G326	K194-S322 WeakPolarHBondContact CD-OG 3.43Å; A318-S322 WeakPolarHBondContact O-CB 3.27Å; A318-S322 PolarHBondContact O-N 3.29Å; V319-S322 VanDerWaalsContact O-CB 3.27Å; V319-S322 WeakPolarHBondContact O-CB 3.36Å; V319-S322 PolarHBondContact O-N 3.45Å; V319-S322 VanDerWaalsContact O-N 3.16Å; A320-S322 VanDerWaalsContact C-N 3.3Å; A320-S322 PolarHBondContact O-N 2.74Å; S322-Y324 PolarHBondContact O-N 3.17Å; S322-G325 PolarHBondContact O-N 2.95Å; S322-G326 PolarHBondContact O-N 3.03Å
323	C	89.2	Confident	86.5	Confident	0 Å²	0	26.8 Å²	26.8	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-64.7	-40.4	179.7	-61.4	0	0	0	0	111.2	S56 I138 F142 V319 A320 G325 G326 L327	S56-C323 VanDerWaalsContact CB-SG 3.53Å; I138-C323 HydrophobicContact CG2-CB 4.04Å; I138-C323 WeakPolarHBondContact CG2-O 3.24Å; F142-C323 HydrophobicContact CB-CB 3.66Å; F142-C323 HydrophobicContact CD2-CB 4.42Å; V319-C323 PolarHBondContact O-N 2.98Å; V319-C323 PolarHBondContact O-SG 2.95Å; A320-C323 PolarHBondContact O-N 2.93Å; C323-G325 PolarHBondContact O-N 3.45Å; C323-G326 PolarHBondContact O-N 3.01Å; C323-L327 VanDerWaalsContact O-CB 3.26Å; C323-L327 WeakPolarHBondContact O-CB 3.4Å; C323-L327 PolarHBondContact O-N 3.48Å
324	Y	88.1	Confident	86.5	Confident	45 Å²	45	19.7 Å²	19.7	18%	0.176	12%	0.121	C	C	.	.	H	α-helix	trans	-59.9	-45.9	175	-174.3	-86.4	0	0	0	111.8	F142 L172 I175 V186 F190 A320 L321 S322 N328	F142-Y324 HydrophobicContact CE2-CD2 4.42Å; L172-Y324 HydrophobicContact CD1-CD2 4.16Å; L172-Y324 HydrophobicContact CD1-CE2 4.14Å; L172-Y324 HydrophobicContact CD2-CD1 4.29Å; L172-Y324 HydrophobicContact CD2-CD2 4.37Å; L172-Y324 HydrophobicContact CD2-CE1 3.61Å; L172-Y324 HydrophobicContact CD2-CE2 3.7Å; L172-Y324 WeakPolarHBondContact CD2-OH 3.3Å; L172-Y324 HydrophobicContact CG-CD2 4.34Å; L172-Y324 HydrophobicContact CG-CE2 3.81Å; I175-Y324 WeakPolarHBondContact CD1-OH 3.39Å; V186-Y324 HydrophobicContact CG1-CE1 4.16Å; F190-Y324 HydrophobicContact CD2-CD1 4.44Å; F190-Y324 AromaticContact CE2-CD1 3.84Å; F190-Y324 HydrophobicContact CE2-CD1 3.84Å; F190-Y324 HydrophobicContact CE2-CE1 4.37Å; A320-Y324 WeakPolarHBondContact O-CB 3.48Å; A320-Y324 PolarHBondContact O-N 3.44Å; L321-Y324 PolarHBondContact O-N 2.92Å; S322-Y324 PolarHBondContact O-N 3.17Å; Y324-N328 WeakPolarHBondContact O-CB 3.49Å; Y324-N328 PolarHBondContact O-N 3.34Å
325	G	83.2	Confident	86.3	Confident	6 Å²	6	17.4 Å²	17.4	6%	0.062	11%	0.11	C	C	.	.	H	α-helix	trans	-63.2	-44.3	175.7	0	0	0	0	0	113	L321 S322 C323 N328 A329	L321-G325 PolarHBondContact O-N 3.19Å; S322-G325 PolarHBondContact O-N 2.95Å; C323-G325 PolarHBondContact O-N 3.45Å; G325-N328 PolarHBondContact O-N 2.99Å; G325-A329 PolarHBondContact O-N 3.29Å
326	G	83.7	Confident	85.8	Confident	22 Å²	22	24 Å²	24	23%	0.227	14%	0.135	C	C	.	.	H	α-helix	trans	-64.2	-41.8	177.4	0	0	0	0	0	113	S322 C323 A329 S330	S322-G326 PolarHBondContact O-N 3.03Å; C323-G326 PolarHBondContact O-N 3.01Å; G326-A329 PolarHBondContact O-N 3.4Å; G326-S330 WeakPolarHBondContact O-CB 3.22Å; G326-S330 PolarHBondContact O-N 2.67Å
327	L	89.1	Confident	85.4	Confident	0 Å²	0	24.2 Å²	24.2	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-63.6	-44.2	176.8	-177.3	55.1	0	0	0	111.3	Q135 I138 A139 I169 L172 C323 A329 S330 I331	Q135-L327 HydrophobicContact CB-CD1 3.66Å; Q135-L327 HydrophobicContact CG-CD1 3.88Å; I138-L327 HydrophobicContact CG2-CB 3.78Å; A139-L327 HydrophobicContact CB-CD2 3.91Å; I169-L327 HydrophobicContact CG1-CD1 4.33Å; I169-L327 HydrophobicContact CG1-CD2 3.86Å; L172-L327 HydrophobicContact CD1-CB 3.82Å; L172-L327 HydrophobicContact CD1-CD2 3.62Å; L172-L327 HydrophobicContact CD1-CG 3.58Å; C323-L327 VanDerWaalsContact O-CB 3.26Å; C323-L327 WeakPolarHBondContact O-CB 3.4Å; C323-L327 PolarHBondContact O-N 3.48Å; L327-A329 PolarHBondContact O-N 2.95Å; L327-S330 PolarHBondContact O-N 3.44Å; L327-I331 HydrophobicContact CD1-CD1 4.13Å; L327-I331 HydrophobicContact CD1-CG1 4.36Å; L327-I331 HydrophobicContact CG-CD1 4.03Å; L327-I331 VanDerWaalsContact O-CG1 3.31Å; L327-I331 WeakPolarHBondContact O-CG1 3.29Å; L327-I331 PolarHBondContact O-N 2.8Å
328	N	86.6	Confident	85.1	Confident	4 Å²	4	20.2 Å²	20.2	2%	0.021	12%	0.115	C	C	.	.	H	α-helix	trans	-59.9	-45.2	175.5	-175.6	69.9	0	0	0	112	L172 N176 G183 Y324 G325 S330 I331 I332	L172-N328 HydrophobicContact CD1-CB 4.32Å; L172-N328 HydrophobicContact CD2-CB 3.86Å; N176-N328 PolarHBondContact ND2-OD1 3.11Å; N176-N328 PolarHBondContact OD1-OD1 2.78Å; G183-N328 PolarHBondContact O-ND2 2.99Å; G183-N328 VanDerWaalsContact O-ND2 3.15Å; Y324-N328 WeakPolarHBondContact O-CB 3.49Å; Y324-N328 PolarHBondContact O-N 3.34Å; G325-N328 PolarHBondContact O-N 2.99Å; N328-S330 PolarHBondContact O-N 2.78Å; N328-I331 PolarHBondContact O-N 2.95Å; N328-I332 WeakPolarHBondContact O-CG1 3.36Å; N328-I332 PolarHBondContact O-N 2.98Å; N328-I332 VanDerWaalsContact O-N 3.11Å
329	A	80.8	Confident	84.4	Confident	20 Å²	20	21.4 Å²	21.4	17%	0.165	12%	0.118	C	C	.	.	H	α-helix	trans	-61.5	-43.6	177.4	0	0	0	0	0	112	G325 G326 L327 I332 A333	G325-A329 PolarHBondContact O-N 3.29Å; G326-A329 PolarHBondContact O-N 3.4Å; L327-A329 PolarHBondContact O-N 2.95Å; A329-I332 PolarHBondContact O-N 3.47Å; A329-A333 WeakPolarHBondContact O-CB 3.34Å; A329-A333 PolarHBondContact O-N 3.01Å
330	S	86.2	Confident	83.8	Confident	17 Å²	17	23.2 Å²	23.2	12%	0.119	13%	0.129	C	C	.	.	H	α-helix	trans	-63.8	-44.1	177.8	179.4	0	0	0	0	112.2	Q135 G326 L327 N328 I332 A333 A334	Q135-S330 WeakPolarHBondContact CG-OG 3.24Å; Q135-S330 PolarHBondContact NE2-OG 3.09Å; G326-S330 WeakPolarHBondContact O-CB 3.22Å; G326-S330 PolarHBondContact O-N 2.67Å; L327-S330 PolarHBondContact O-N 3.44Å; N328-S330 PolarHBondContact O-N 2.78Å; S330-I332 VanDerWaalsContact C-N 3.33Å; S330-I332 PolarHBondContact O-N 3.03Å; S330-A333 PolarHBondContact O-N 3.14Å; S330-A334 WeakPolarHBondContact O-CB 3.44Å; S330-A334 PolarHBondContact O-N 3.49Å
331	I	88.6	Confident	83.3	Confident	0 Å²	0	23 Å²	23	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-59.6	-43.9	176.7	-71.5	167.4	0	0	0	111.1	Q135 L172 L327 N328 S335 L365	Q135-I331 HydrophobicContact CG-CG1 4.48Å; L172-I331 HydrophobicContact CB-CD1 3.8Å; L172-I331 HydrophobicContact CD1-CD1 4.45Å; L327-I331 HydrophobicContact CD1-CD1 4.13Å; L327-I331 HydrophobicContact CD1-CG1 4.36Å; L327-I331 HydrophobicContact CG-CD1 4.03Å; L327-I331 VanDerWaalsContact O-CG1 3.31Å; L327-I331 WeakPolarHBondContact O-CG1 3.29Å; L327-I331 PolarHBondContact O-N 2.8Å; N328-I331 PolarHBondContact O-N 2.95Å; I331-S335 PolarHBondContact O-N 3.02Å; I331-S335 VanDerWaalsContact O-N 3.14Å; I331-L365 HydrophobicContact CG2-CD2 3.44Å; I331-L365 VanDerWaalsContact CG2-CD2 3.44Å
332	I	82.3	Confident	83	Confident	19 Å²	19	20.2 Å²	20.2	10%	0.097	11%	0.113	C	C	.	.	H	α-helix	trans	-64.5	-46.1	176.6	-66.4	169.3	0	0	0	110.6	N176 N328 A329 S330 S335 R336	N176-I332 WeakPolarHBondContact OD1-CD1 3.48Å; N176-I332 WeakPolarHBondContact OD1-CG1 3.44Å; N328-I332 WeakPolarHBondContact O-CG1 3.36Å; N328-I332 PolarHBondContact O-N 2.98Å; N328-I332 VanDerWaalsContact O-N 3.11Å; A329-I332 PolarHBondContact O-N 3.47Å; S330-I332 VanDerWaalsContact C-N 3.33Å; S330-I332 PolarHBondContact O-N 3.03Å; I332-S335 PolarHBondContact O-N 2.91Å; I332-S335 PolarHBondContact O-OG 2.96Å; I332-R336 PolarHBondContact O-N 2.7Å
333	A	80.6	Confident	82.4	Confident	51 Å²	51	25.6 Å²	25.6	42%	0.421	13%	0.133	S	C	.	.	H	α-helix	trans	-61	-46.6	-180	0	0	0	0	0	112.1	A329 S330 S335 R336 L337	A329-A333 WeakPolarHBondContact O-CB 3.34Å; A329-A333 PolarHBondContact O-N 3.01Å; S330-A333 PolarHBondContact O-N 3.14Å; A333-S335 PolarHBondContact O-N 3.18Å; A333-R336 PolarHBondContact O-N 3.42Å; A333-L337 PolarHBondContact O-N 3.23Å
334	A	85.4	Confident	82	Confident	0 Å²	0	30.8 Å²	30.8	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-59	-45.2	177.6	0	0	0	0	0	111.7	E131 S330 R336 L337 F338	E131-A334 HydrophobicContact CB-CB 3.87Å; E131-A334 HydrophobicContact CG-CB 3.86Å; S330-A334 WeakPolarHBondContact O-CB 3.44Å; S330-A334 PolarHBondContact O-N 3.49Å; A334-R336 VanDerWaalsContact C-N 3.29Å; A334-R336 PolarHBondContact O-N 3.22Å; A334-L337 PolarHBondContact O-N 3.4Å; A334-F338 HydrophobicContact CB-CE2 4.36Å; A334-F338 HydrophobicContact CB-CZ 4.17Å; A334-F338 WeakPolarHBondContact O-CD1 3.34Å; A334-F338 WeakPolarHBondContact O-CG 3.17Å; A334-F338 PolarHBondContact O-N 3.3Å
335	S	82.4	Confident	81.7	Confident	8 Å²	8	30.7 Å²	30.7	6%	0.056	17%	0.17	C	C	.	.	H	α-helix	trans	-60.5	-36.8	177.9	73	0	0	0	0	113.2	I331 I332 A333 F338 F339	I331-S335 PolarHBondContact O-N 3.02Å; I331-S335 VanDerWaalsContact O-N 3.14Å; I332-S335 PolarHBondContact O-N 2.91Å; I332-S335 PolarHBondContact O-OG 2.96Å; A333-S335 PolarHBondContact O-N 3.18Å; S335-F338 PolarHBondContact O-N 3.03Å; S335-F339 WeakPolarHBondContact O-CB 3.32Å; S335-F339 PolarHBondContact O-N 2.81Å
336	R	77.6	Confident	81.7	Confident	140 Å²	140	31.2 Å²	31.2	53%	0.528	17%	0.171	S	C	.	.	H	α-helix	trans	-69	-41.2	176.3	-70.4	178.8	179.8	-168.3	-0.6	111.8	I332 A333 A334 F338 F339 V340	I332-R336 PolarHBondContact O-N 2.7Å; A333-R336 PolarHBondContact O-N 3.42Å; A334-R336 VanDerWaalsContact C-N 3.29Å; A334-R336 PolarHBondContact O-N 3.22Å; R336-F338 VanDerWaalsContact C-N 3.31Å; R336-F338 PolarHBondContact O-N 3.41Å; R336-F339 PolarHBondContact O-N 2.75Å; R336-V340 WeakPolarHBondContact O-CG2 3.42Å; R336-V340 PolarHBondContact O-N 2.8Å
337	L	81.5	Confident	81.8	Confident	11 Å²	11	30.7 Å²	30.7	6%	0.058	16%	0.163	C	C	.	.	H	α-helix	trans	-60.3	-43.2	176.2	179.7	62.9	0	0	0	111.1	L123 A333 A334 V340 G341	L123-L337 HydrophobicContact CD1-CD1 3.99Å; L123-L337 HydrophobicContact CD1-CD2 4.38Å; L123-L337 HydrophobicContact CD1-CG 3.83Å; A333-L337 PolarHBondContact O-N 3.23Å; A334-L337 PolarHBondContact O-N 3.4Å; L337-V340 PolarHBondContact O-N 2.8Å; L337-G341 PolarHBondContact O-N 3.49Å
338	F	82.5	Confident	81.5	Confident	0 Å²	0	33.2 Å²	33.2	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-68	-38.6	179.6	-57.2	-14.3	0	0	0	111.8	L127 E131 A334 S335 R336 G341 S342 L347 A364 F367 N368	L127-F338 HydrophobicContact CB-CD1 4.24Å; L127-F338 HydrophobicContact CB-CE1 3.59Å; L127-F338 HydrophobicContact CB-CZ 3.98Å; L127-F338 HydrophobicContact CD1-CD1 3.87Å; L127-F338 HydrophobicContact CD1-CD2 4.43Å; L127-F338 HydrophobicContact CD1-CE1 3.96Å; L127-F338 HydrophobicContact CD1-CE2 4.47Å; L127-F338 HydrophobicContact CD1-CG 4.15Å; L127-F338 HydrophobicContact CD1-CZ 4.27Å; L127-F338 HydrophobicContact CG-CD1 4.27Å; L127-F338 HydrophobicContact CG-CE1 3.83Å; L127-F338 HydrophobicContact CG-CE2 4.36Å; L127-F338 HydrophobicContact CG-CZ 3.88Å; E131-F338 HydrophobicContact CG-CE1 4.39Å; E131-F338 HydrophobicContact CG-CZ 4.34Å; A334-F338 HydrophobicContact CB-CE2 4.36Å; A334-F338 HydrophobicContact CB-CZ 4.17Å; A334-F338 WeakPolarHBondContact O-CD1 3.34Å; A334-F338 WeakPolarHBondContact O-CG 3.17Å; A334-F338 PolarHBondContact O-N 3.3Å; S335-F338 PolarHBondContact O-N 3.03Å; R336-F338 VanDerWaalsContact C-N 3.31Å; R336-F338 PolarHBondContact O-N 3.41Å; F338-G341 PolarHBondContact O-N 2.92Å; F338-S342 PolarHBondContact O-N 3.39Å; F338-L347 HydrophobicContact CB-CD1 4.41Å; F338-A364 HydrophobicContact CB-CB 4.22Å; F338-A364 HydrophobicContact CD2-CB 4.18Å; F338-F367 HydrophobicContact CE2-CD1 4.26Å; F338-N368 HydrophobicContact CE2-CB 3.98Å
339	F	74.4	Confident	81.2	Confident	37 Å²	37	36.7 Å²	36.7	16%	0.162	20%	0.198	C	C	.	.	H	α-helix	trans	-60.7	-48	173.7	-179.5	-95.9	0	0	0	112.1	S335 R336 S342 R343 S352 I354 T495	S335-F339 WeakPolarHBondContact O-CB 3.32Å; S335-F339 PolarHBondContact O-N 2.81Å; R336-F339 PolarHBondContact O-N 2.75Å; F339-S342 PolarHBondContact O-N 2.75Å; F339-R343 VanDerWaalsContact CE1-CD 3.41Å; F339-R343 HydrophobicContact CE1-CG 4.18Å; F339-R343 HydrophobicContact CZ-CG 4.33Å; F339-R343 PolarHBondContact O-N 2.91Å; F339-S352 WeakPolarHBondContact CD2-O 3.25Å; F339-S352 WeakPolarHBondContact CE2-O 3.42Å; F339-I354 HydrophobicContact CD2-CD1 4.47Å; F339-I354 HydrophobicContact CE2-CD1 3.76Å; F339-I354 HydrophobicContact CE2-CG1 4.03Å; F339-I354 HydrophobicContact CZ-CD1 4.21Å; F339-T495 HydrophobicContact CE2-CG2 3.74Å; F339-T495 HydrophobicContact CZ-CG2 3.79Å
340	V	75.1	Confident	81.2	Confident	39 Å²	39	35.9 Å²	35.9	24%	0.236	19%	0.191	C	C	.	.	H	α-helix	trans	-63.6	-43.8	176.9	172.6	0	0	0	0	111.3	Y107 R336 L337 S342 R343 E344	Y107-V340 HydrophobicContact CE1-CG1 4.4Å; R336-V340 WeakPolarHBondContact O-CG2 3.42Å; R336-V340 PolarHBondContact O-N 2.8Å; L337-V340 PolarHBondContact O-N 2.8Å; V340-S342 VanDerWaalsContact C-N 3.28Å; V340-S342 PolarHBondContact O-N 3.11Å; V340-R343 PolarHBondContact O-N 3.39Å; V340-R343 VanDerWaalsContact O-N 3.14Å; V340-E344 PolarHBondContact O-N 2.95Å; V340-E344 VanDerWaalsContact O-N 3.15Å
341	G	79.9	Confident	81	Confident	0 Å²	0	36.1 Å²	36.1	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-60	-36.9	177.9	0	0	0	0	0	113.6	L123 L337 F338 H346 L347	L123-G341 VanDerWaalsContact CD2-CA 3.48Å; L337-G341 PolarHBondContact O-N 3.49Å; F338-G341 PolarHBondContact O-N 2.92Å; G341-H346 WeakPolarHBondContact O-CB 3.27Å; G341-H346 PolarHBondContact O-N 3.5Å; G341-H346 VanDerWaalsContact O-N 3.12Å; G341-L347 PolarHBondContact O-N 2.91Å
342	S	79	Confident	80.5	Confident	4 Å²	4	36.3 Å²	36.3	3%	0.028	19%	0.192	C	C	.	.	H	α-helix	trans	-74.2	-35	174.5	173.6	0	0	0	0	112.5	F338 F339 V340 E344 G345 L347 P348 S352	F338-S342 PolarHBondContact O-N 3.39Å; F339-S342 PolarHBondContact O-N 2.75Å; V340-S342 VanDerWaalsContact C-N 3.28Å; V340-S342 PolarHBondContact O-N 3.11Å; S342-E344 VanDerWaalsContact C-N 3.25Å; S342-E344 PolarHBondContact O-N 3.32Å; S342-G345 PolarHBondContact O-N 3.41Å; S342-L347 PolarHBondContact OG-O 2.92Å; S342-P348 PolarHBondContact OG-O 3.3Å; S342-S352 WeakPolarHBondContact OG-CB 3.41Å; S342-S352 PolarHBondContact OG-OG 3.15Å
343	R	74.9	Confident	80.5	Confident	115 Å²	115	35.4 Å²	35.4	43%	0.434	19%	0.188	S	C	.	.	H	α-helix	trans	-60.8	-32.7	173.6	-75.9	-174.5	67.6	168.1	7	113.5	F339 V340 G345 D498	F339-R343 VanDerWaalsContact CE1-CD 3.41Å; F339-R343 HydrophobicContact CE1-CG 4.18Å; F339-R343 HydrophobicContact CZ-CG 4.33Å; F339-R343 PolarHBondContact O-N 2.91Å; V340-R343 PolarHBondContact O-N 3.39Å; V340-R343 VanDerWaalsContact O-N 3.14Å; R343-G345 PolarHBondContact O-N 3.02Å; R343-D498 IonicContact CZ-OD2 2.67Å; R343-D498 IonicContact NH2-OD2 2.7Å; R343-D498 PolarHBondContact NH2-OD2 3.29Å
344	E	80.8	Confident	80.7	Confident	108 Å²	108	34.7 Å²	34.7	51%	0.505	18%	0.176	S	C	.	.	T	Hydrogen-bonded Turn	trans	-78.8	4.9	174.5	-66.3	-69.4	151.3	0	0	113	Y107 V340 S342 H346	Y107-E344 HydrophobicContact CE1-CG 4.12Å; Y107-E344 VanDerWaalsContact OH-CB 3.3Å; Y107-E344 WeakPolarHBondContact OH-CB 3.44Å; V340-E344 PolarHBondContact O-N 2.95Å; V340-E344 VanDerWaalsContact O-N 3.15Å; S342-E344 VanDerWaalsContact C-N 3.25Å; S342-E344 PolarHBondContact O-N 3.32Å; E344-H346 PolarHBondContact O-N 3.41Å
345	G	81.1	Confident	80.8	Confident	44 Å²	44	35.7 Å²	35.7	45%	0.454	18%	0.181	S	C	.	.	T	Hydrogen-bonded Turn	trans	72.1	10.8	-179.4	0	0	0	0	0	114.3	S342 R343	S342-G345 PolarHBondContact O-N 3.41Å; R343-G345 PolarHBondContact O-N 3.02Å
346	H	84.1	Confident	80.8	Confident	17 Å²	17	39.7 Å²	39.7	8%	0.079	20%	0.201	C	C	.	.	S	Bend	trans	-87.6	-21	-179	-75.3	174.5	0	0	0	113.2	Y107 G116 F120 L123 G341 E344	Y107-H346 AromaticContact CE2-ND1 3.78Å; Y107-H346 AromaticContact CZ-ND1 3.72Å; Y107-H346 PolarHBondContact OH-CE1 3.4Å; Y107-H346 PolarHBondContact OH-ND1 3.43Å; G116-H346 PolarHBondContact O-CE1 2.91Å; F120-H346 HydrophobicContact CD2-CB 4.01Å; F120-H346 WeakPolarHBondContact CD2-O 3.23Å; F120-H346 WeakPolarHBondContact CE2-O 3.27Å; L123-H346 HydrophobicContact CD2-CB 3.95Å; G341-H346 WeakPolarHBondContact O-CB 3.27Å; G341-H346 PolarHBondContact O-N 3.5Å; G341-H346 VanDerWaalsContact O-N 3.12Å; E344-H346 PolarHBondContact O-N 3.41Å
347	L	84.4	Confident	81.1	Confident	10 Å²	10	40.8 Å²	40.8	5%	0.052	21%	0.212	C	C	.	.	S	Bend	trans	-122.3	153.7	176.1	-70.2	172.3	0	0	0	111.1	L123 L127 F338 G341 S342 D349 L351	L123-L347 HydrophobicContact CD1-CD1 4.27Å; L123-L347 HydrophobicContact CD2-CD1 3.75Å; L123-L347 HydrophobicContact CD2-CD2 4.41Å; L123-L347 HydrophobicContact CD2-CG 3.73Å; L123-L347 HydrophobicContact CG-CD1 4.05Å; L123-L347 HydrophobicContact CG-CG 4.35Å; L127-L347 HydrophobicContact CD1-CD1 3.92Å; L127-L347 HydrophobicContact CD1-CD2 3.96Å; F338-L347 HydrophobicContact CB-CD1 4.41Å; G341-L347 PolarHBondContact O-N 2.91Å; S342-L347 PolarHBondContact OG-O 2.92Å; L347-D349 PolarHBondContact O-N 3.44Å; L347-L351 HydrophobicContact CB-CD1 4.47Å
348	P	82.7	Confident	81	Confident	54 Å²	54	45.9 Å²	45.9	35%	0.351	23%	0.23	S	C	.	.			trans	-54.1	139.7	175.7	-25.5	34.4	0	0	0	112.5	S342 A350 L351 L479	S342-P348 PolarHBondContact OG-O 3.3Å; P348-A350 PolarHBondContact O-N 3.02Å; P348-L351 PolarHBondContact O-N 2.87Å; P348-L479 HydrophobicContact CB-CD2 4.04Å; P348-L479 HydrophobicContact CG-CD2 4.04Å
349	D	80.1	Confident	81	Confident	76 Å²	76	53.7 Å²	53.7	41%	0.406	26%	0.264	S	S	.	.	G	3₁₀ helix	trans	-57.1	-25	-178.6	-58.5	-26.2	0	0	0	113.6	L347 L351 S352 M353 L494	L347-D349 PolarHBondContact O-N 3.44Å; D349-L351 PolarHBondContact O-N 3.35Å; D349-S352 PolarHBondContact O-N 3.31Å; D349-S352 VanDerWaalsContact O-N 3.11Å; D349-S352 PolarHBondContact O-OG 3.48Å; D349-M353 WeakPolarHBondContact O-CG 3.22Å; D349-M353 PolarHBondContact O-N 2.92Å; D349-L494 HydrophobicContact CB-CD1 3.84Å; D349-L494 HydrophobicContact CB-CD2 4.08Å; D349-L494 HydrophobicContact CB-CG 4.33Å
350	A	81.5	Confident	81.4	Confident	3 Å²	3	51.9 Å²	51.9	3%	0.025	26%	0.257	C	S	.	.	G	3₁₀ helix	trans	-54.8	-32.3	173.9	0	0	0	0	0	113	P348 M353 P363 L482	P348-A350 PolarHBondContact O-N 3.02Å; A350-M353 HydrophobicContact CB-CE 4.48Å; A350-P363 VanDerWaalsContact O-CB 3.22Å; A350-P363 WeakPolarHBondContact O-CB 3.45Å; A350-P363 WeakPolarHBondContact O-CG 3.49Å; A350-L482 HydrophobicContact CB-CD2 4.06Å; A350-L482 HydrophobicContact CB-CG 4.37Å
351	L	81.5	Confident	82	Confident	23 Å²	23	51.1 Å²	51.1	12%	0.12	25%	0.252	C	S	.	.	G	3₁₀ helix	trans	-83.5	-14.9	-179	-64.7	176.8	0	0	0	113.7	L127 L347 P348 D349 F367	L127-L351 HydrophobicContact CD1-CD1 4.23Å; L347-L351 HydrophobicContact CB-CD1 4.47Å; P348-L351 PolarHBondContact O-N 2.87Å; D349-L351 PolarHBondContact O-N 3.35Å; L351-F367 HydrophobicContact CD2-CB 4.02Å; L351-F367 HydrophobicContact CD2-CG 4.29Å
352	S	78.3	Confident	82.4	Confident	4 Å²	4	52 Å²	52	3%	0.028	26%	0.257	C	S	.	.	G	3₁₀ helix	trans	-93.4	-2.2	171.6	48.7	0	0	0	0	113.9	F339 S342 D349	F339-S352 WeakPolarHBondContact CD2-O 3.25Å; F339-S352 WeakPolarHBondContact CE2-O 3.42Å; S342-S352 WeakPolarHBondContact OG-CB 3.41Å; S342-S352 PolarHBondContact OG-OG 3.15Å; D349-S352 PolarHBondContact O-N 3.31Å; D349-S352 VanDerWaalsContact O-N 3.11Å; D349-S352 PolarHBondContact O-OG 3.48Å
353	M	83.5	Confident	82.8	Confident	0 Å²	0	52.4 Å²	52.4	0%	0	26%	0.26	C	S	.	.			trans	-69.7	145.8	-177.3	-56.4	-178.3	177.8	0	0	112.5	D349 A350 P363 T483 T486 Q487 C492 V493 L494	D349-M353 WeakPolarHBondContact O-CG 3.22Å; D349-M353 PolarHBondContact O-N 2.92Å; A350-M353 HydrophobicContact CB-CE 4.48Å; M353-P363 HydrophobicContact CB-CG 4.37Å; M353-T483 HydrophobicContact CE-CG2 3.25Å; M353-T486 HydrophobicContact SD-CG2 3.97Å; M353-Q487 HydrophobicContact CE-CG 3.68Å; M353-Q487 HydrophobicContact SD-CG 3.61Å; M353-C492 HydrophobicContact CB-CB 3.67Å; M353-C492 HydrophobicContact SD-CB 4.42Å; M353-V493 WeakPolarHBondContact CA-O 3.48Å; M353-L494 HydrophobicContact CE-CD1 3.68Å; M353-L494 HydrophobicContact CG-CD1 4.02Å
354	I	84.8	Confident	83.4	Confident	35 Å²	35	47 Å²	47	18%	0.179	24%	0.239	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-120.1	139.3	-179.4	-61	-171.4	0	0	0	109.9	F339 F359 C492 V493 T495	F339-I354 HydrophobicContact CD2-CD1 4.47Å; F339-I354 HydrophobicContact CE2-CD1 3.76Å; F339-I354 HydrophobicContact CE2-CG1 4.03Å; F339-I354 HydrophobicContact CZ-CD1 4.21Å; I354-F359 VanDerWaalsContact CG2-CA 3.4Å; I354-F359 HydrophobicContact CG2-CB 4.34Å; I354-C492 CarbonylContact O-C 3.38Å; I354-C492 VanDerWaalsContact O-CA 3.25Å; I354-C492 WeakPolarHBondContact O-CA 3.49Å; I354-V493 PolarHBondContact N-O 3.4Å; I354-V493 PolarHBondContact O-N 3.22Å; I354-T495 HydrophobicContact CB-CG2 4.39Å; I354-T495 HydrophobicContact CD1-CG2 3.27Å; I354-T495 HydrophobicContact CG1-CG2 3.74Å
355	H	86.1	Confident	83.9	Confident	21 Å²	21	42 Å²	42	10%	0.097	22%	0.216	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-67.2	131.7	176.7	-176	-67.5	0	0	0	112.1	Q357 R358 F359 T360 I362 C490	H355-Q357 PolarHBondContact ND1-N 2.76Å; H355-Q357 VanDerWaalsContact ND1-N 3.14Å; H355-Q357 PolarHBondContact O-N 2.87Å; H355-R358 HydrophobicContact CB-CB 4.29Å; H355-R358 PolarHBondContact ND1-N 2.92Å; H355-R358 PolarHBondContact O-N 2.97Å; H355-F359 WeakPolarHBondContact O-CA 3.49Å; H355-F359 PolarHBondContact O-N 3.38Å; H355-T360 PolarHBondContact N-O 3.45Å; H355-I362 HydrophobicContact CB-CD1 3.72Å; H355-I362 HydrophobicContact CB-CG1 4.14Å; H355-I362 VanDerWaalsContact CD2-CD1 3.42Å; H355-I362 WeakPolarHBondContact CD2-CD1 3.4Å; H355-C490 PolarHBondContact CD2-O 3.17Å
356	I	84	Confident	84.4	Confident	92 Å²	92	43.3 Å²	43.3	47%	0.472	21%	0.212	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57.3	-46.1	-170	-61.5	161.3	0	0	0	113.3	F491 V493	I356-F491 WeakPolarHBondContact CG1-O 3.43Å; I356-F491 PolarHBondContact N-O 3.3Å; I356-V493 HydrophobicContact CD1-CG1 3.92Å; I356-V493 HydrophobicContact CG1-CB 4.46Å; I356-V493 HydrophobicContact CG1-CG1 3.74Å; I356-V493 HydrophobicContact CG1-CG2 3.97Å
357	Q	83.6	Confident	84.7	Confident	163 Å²	163	45.5 Å²	45.5	76%	0.762	22%	0.221	S	C	*	.	T	Hydrogen-bonded Turn	trans	-90.2	-26.2	-176.2	-60.5	177.2	-4.9	0	0	114.5	H355	H355-Q357 PolarHBondContact ND1-N 2.76Å; H355-Q357 VanDerWaalsContact ND1-N 3.14Å; H355-Q357 PolarHBondContact O-N 2.87Å
358	R	79.6	Confident	85.1	Confident	119 Å²	119	45 Å²	45	45%	0.449	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-104.5	-16.9	-167.7	-61	175.4	-173.8	-108	8.9	112.4	A178 H355 T360	A178-R358 WeakPolarHBondContact O-CD 3.21Å; A178-R358 PolarHBondContact O-NH1 3.38Å; H355-R358 HydrophobicContact CB-CB 4.29Å; H355-R358 PolarHBondContact ND1-N 2.92Å; H355-R358 PolarHBondContact O-N 2.97Å; R358-T360 HydrophobicContact CB-CG2 4.07Å; R358-T360 WeakPolarHBondContact O-CG2 3.44Å; R358-T360 PolarHBondContact O-N 2.87Å
359	F	82.3	Confident	85.7	Confident	163 Å²	163	43 Å²	43	72%	0.715	21%	0.206	S	C	*	.			trans	55.7	37.2	-177.6	-56.4	-84.3	0	0	0	112.8	I354 H355	I354-F359 VanDerWaalsContact CG2-CA 3.4Å; I354-F359 HydrophobicContact CG2-CB 4.34Å; H355-F359 WeakPolarHBondContact O-CA 3.49Å; H355-F359 PolarHBondContact O-N 3.38Å
360	T	82.8	Confident	86.4	Confident	0 Å²	0	43.8 Å²	43.8	0%	0	21%	0.209	C	C	.	.			trans	-115.3	141.9	-178.3	59.3	0	0	0	0	112	S177 V180 H355 R358 I362	S177-T360 PolarHBondContact O-OG1 2.92Å; V180-T360 HydrophobicContact CG2-CG2 3.36Å; H355-T360 PolarHBondContact N-O 3.45Å; R358-T360 HydrophobicContact CB-CG2 4.07Å; R358-T360 WeakPolarHBondContact O-CG2 3.44Å; R358-T360 PolarHBondContact O-N 2.87Å; T360-I362 VanDerWaalsContact C-N 3.29Å; T360-I362 PolarHBondContact O-N 3.46Å; T360-I362 WeakPolarHBondContact OG1-CG1 3.36Å
361	P	86.6	Confident	87	Confident	22 Å²	22	45 Å²	45	14%	0.143	21%	0.214	C	C	.	.			trans	-83.3	68.9	179.3	34.8	-36.2	0	0	0	111.4	P363 A364 L365	P361-P363 VanDerWaalsContact C-CD 3.5Å; P361-A364 HydrophobicContact CB-CB 4.35Å; P361-A364 PolarHBondContact O-N 3.22Å; P361-L365 WeakPolarHBondContact O-CG 3.33Å; P361-L365 PolarHBondContact O-N 2.73Å
362	I	87.9	Confident	87.7	Confident	20 Å²	20	43.9 Å²	43.9	10%	0.103	21%	0.209	C	C	.	.	H	α-helix	trans	-55	-45.1	-174.6	-60.5	-177.7	0	0	0	113.3	H355 T360 A364 L365 I366 C490	H355-I362 HydrophobicContact CB-CD1 3.72Å; H355-I362 HydrophobicContact CB-CG1 4.14Å; H355-I362 VanDerWaalsContact CD2-CD1 3.42Å; H355-I362 WeakPolarHBondContact CD2-CD1 3.4Å; T360-I362 VanDerWaalsContact C-N 3.29Å; T360-I362 PolarHBondContact O-N 3.46Å; T360-I362 WeakPolarHBondContact OG1-CG1 3.36Å; I362-A364 VanDerWaalsContact C-N 3.34Å; I362-A364 PolarHBondContact O-N 3.13Å; I362-L365 WeakPolarHBondContact O-CB 3.25Å; I362-L365 PolarHBondContact O-N 3.34Å; I362-I366 HydrophobicContact CG2-CD1 3.57Å; I362-I366 HydrophobicContact CG2-CG1 4.09Å; I362-I366 WeakPolarHBondContact O-CG1 3.34Å; I362-I366 PolarHBondContact O-N 3.19Å; I362-C490 HydrophobicContact CG2-CB 4.34Å
363	P	88.6	Confident	88.6	Confident	12 Å²	12	46.3 Å²	46.3	8%	0.078	22%	0.221	C	C	.	.	H	α-helix	trans	-63.8	-39.3	-176.6	-24.1	36.8	0	0	0	113	A350 M353 P361 I366 F367 T486	A350-P363 VanDerWaalsContact O-CB 3.22Å; A350-P363 WeakPolarHBondContact O-CB 3.45Å; A350-P363 WeakPolarHBondContact O-CG 3.49Å; M353-P363 HydrophobicContact CB-CG 4.37Å; P361-P363 VanDerWaalsContact C-CD 3.5Å; P363-I366 PolarHBondContact O-N 2.76Å; P363-F367 WeakPolarHBondContact O-CB 3.23Å; P363-F367 PolarHBondContact O-N 3.4Å; P363-T486 HydrophobicContact CB-CG2 3.68Å; P363-T486 HydrophobicContact CG-CG2 3.23Å
364	A	87.8	Confident	89.2	Confident	0 Å²	0	50.6 Å²	50.6	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-64	-41.6	175.3	0	0	0	0	0	111.8	F338 P361 I362 F367 N368	F338-A364 HydrophobicContact CB-CB 4.22Å; F338-A364 HydrophobicContact CD2-CB 4.18Å; P361-A364 HydrophobicContact CB-CB 4.35Å; P361-A364 PolarHBondContact O-N 3.22Å; I362-A364 VanDerWaalsContact C-N 3.34Å; I362-A364 PolarHBondContact O-N 3.13Å; A364-F367 PolarHBondContact O-N 2.74Å; A364-N368 VanDerWaalsContact O-CB 3.3Å; A364-N368 WeakPolarHBondContact O-CB 3.28Å; A364-N368 PolarHBondContact O-N 3.27Å
365	L	90.1	Very high	89.6	Confident	3 Å²	3	50.1 Å²	50.1	2%	0.016	24%	0.239	C	C	.	.	H	α-helix	trans	-63.7	-44.6	176.8	-69.6	170.4	0	0	0	111.8	T173 N176 I331 P361 I362 N368 C369	T173-L365 HydrophobicContact CG2-CB 4.12Å; N176-L365 HydrophobicContact CB-CD1 4.09Å; N176-L365 HydrophobicContact CB-CD2 4.24Å; I331-L365 HydrophobicContact CG2-CD2 3.44Å; I331-L365 VanDerWaalsContact CG2-CD2 3.44Å; P361-L365 WeakPolarHBondContact O-CG 3.33Å; P361-L365 PolarHBondContact O-N 2.73Å; I362-L365 WeakPolarHBondContact O-CB 3.25Å; I362-L365 PolarHBondContact O-N 3.34Å; L365-N368 PolarHBondContact O-N 2.91Å; L365-C369 VanDerWaalsContact O-CB 3.29Å; L365-C369 WeakPolarHBondContact O-CB 3.35Å; L365-C369 PolarHBondContact O-N 2.97Å
366	I	91.8	Very high	90	Very high	73 Å²	73	49.6 Å²	49.6	37%	0.374	24%	0.237	S	C	.	.	H	α-helix	trans	-63.7	-46.1	177.5	-68.4	173.4	0	0	0	110.6	I362 P363 N368 C369 I370	I362-I366 HydrophobicContact CG2-CD1 3.57Å; I362-I366 HydrophobicContact CG2-CG1 4.09Å; I362-I366 WeakPolarHBondContact O-CG1 3.34Å; I362-I366 PolarHBondContact O-N 3.19Å; P363-I366 PolarHBondContact O-N 2.76Å; I366-N368 VanDerWaalsContact C-N 3.35Å; I366-N368 PolarHBondContact O-N 3.35Å; I366-C369 WeakPolarHBondContact O-CB 3.49Å; I366-C369 PolarHBondContact O-N 3.1Å; I366-I370 HydrophobicContact CG2-CD1 3.79Å; I366-I370 HydrophobicContact CG2-CG1 4.4Å; I366-I370 WeakPolarHBondContact O-CG1 3.4Å; I366-I370 PolarHBondContact O-N 3.35Å
367	F	91.3	Very high	90.4	Very high	62 Å²	62	50.2 Å²	50.2	27%	0.272	25%	0.245	S	C	.	.	H	α-helix	trans	-57.5	-49.4	177.8	177.9	-88.1	0	0	0	111.4	L127 L128 F338 L351 P363 A364 C369 I370 M371	L127-F367 HydrophobicContact CD1-CE1 4.12Å; L127-F367 HydrophobicContact CD2-CD1 4.27Å; L127-F367 HydrophobicContact CD2-CE1 3.18Å; L127-F367 HydrophobicContact CD2-CE2 4.48Å; L127-F367 HydrophobicContact CD2-CZ 3.32Å; L127-F367 HydrophobicContact CG-CD1 4.22Å; L127-F367 HydrophobicContact CG-CE1 3.48Å; L127-F367 VanDerWaalsContact CG-CE1 3.48Å; L127-F367 HydrophobicContact CG-CZ 4.14Å; L128-F367 HydrophobicContact CD2-CZ 4.16Å; F338-F367 HydrophobicContact CE2-CD1 4.26Å; L351-F367 HydrophobicContact CD2-CB 4.02Å; L351-F367 HydrophobicContact CD2-CG 4.29Å; P363-F367 WeakPolarHBondContact O-CB 3.23Å; P363-F367 PolarHBondContact O-N 3.4Å; A364-F367 PolarHBondContact O-N 2.74Å; F367-C369 VanDerWaalsContact C-N 3.32Å; F367-C369 PolarHBondContact O-N 3.39Å; F367-I370 PolarHBondContact O-N 3.42Å; F367-M371 HydrophobicContact CD1-CG 4.19Å; F367-M371 HydrophobicContact CE1-CG 3.53Å; F367-M371 HydrophobicContact CE2-CG 4.3Å; F367-M371 HydrophobicContact CZ-CG 3.61Å; F367-M371 HydrophobicContact CZ-SD 4.05Å; F367-M371 WeakPolarHBondContact O-CG 3.33Å; F367-M371 PolarHBondContact O-N 3.45Å
368	N	92.1	Very high	90.8	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-61.6	-39.8	178.6	-172.1	47.7	0	0	0	112.5	Q135 F338 A364 L365 I366 M371 S372	Q135-N368 PolarHBondContact NE2-ND2 3.34Å; Q135-N368 PolarHBondContact NE2-OD1 3.26Å; Q135-N368 VanDerWaalsContact NE2-OD1 3.13Å; Q135-N368 PolarHBondContact OE1-ND2 3.24Å; Q135-N368 PolarHBondContact OE1-OD1 2.71Å; F338-N368 HydrophobicContact CE2-CB 3.98Å; A364-N368 VanDerWaalsContact O-CB 3.3Å; A364-N368 WeakPolarHBondContact O-CB 3.28Å; A364-N368 PolarHBondContact O-N 3.27Å; L365-N368 PolarHBondContact O-N 2.91Å; I366-N368 VanDerWaalsContact C-N 3.35Å; I366-N368 PolarHBondContact O-N 3.35Å; N368-M371 PolarHBondContact O-N 2.88Å; N368-S372 WeakPolarHBondContact O-CB 3.34Å; N368-S372 PolarHBondContact O-N 2.9Å; N368-S372 PolarHBondContact O-OG 3.49Å
369	C	94.9	Very high	91.2	Very high	13 Å²	13	45.4 Å²	45.4	9%	0.088	23%	0.23	C	C	.	.	H	α-helix	trans	-61.7	-50.1	175.4	178.3	0	0	0	0	111.3	I169 T173 L365 I366 F367 M371 S372 L373	I169-C369 HydrophobicContact CG2-CB 4.48Å; T173-C369 HydrophobicContact CG2-CB 3.7Å; T173-C369 WeakPolarHBondContact OG1-CB 3.42Å; L365-C369 VanDerWaalsContact O-CB 3.29Å; L365-C369 WeakPolarHBondContact O-CB 3.35Å; L365-C369 PolarHBondContact O-N 2.97Å; I366-C369 WeakPolarHBondContact O-CB 3.49Å; I366-C369 PolarHBondContact O-N 3.1Å; F367-C369 VanDerWaalsContact C-N 3.32Å; F367-C369 PolarHBondContact O-N 3.39Å; C369-M371 VanDerWaalsContact C-N 3.33Å; C369-M371 PolarHBondContact O-N 3.22Å; C369-S372 PolarHBondContact O-N 3.45Å; C369-S372 VanDerWaalsContact O-N 3.16Å; C369-L373 VanDerWaalsContact O-CG 3.31Å; C369-L373 WeakPolarHBondContact O-CG 3.19Å; C369-L373 PolarHBondContact O-N 3.46Å
370	I	95.6	Very high	91.5	Very high	92 Å²	92	41.1 Å²	41.1	47%	0.472	21%	0.214	S	C	.	.	H	α-helix	trans	-58	-47.1	178	-67.8	167.3	0	0	0	110.5	I366 F367 S372 L373 I374	I366-I370 HydrophobicContact CG2-CD1 3.79Å; I366-I370 HydrophobicContact CG2-CG1 4.4Å; I366-I370 WeakPolarHBondContact O-CG1 3.4Å; I366-I370 PolarHBondContact O-N 3.35Å; F367-I370 PolarHBondContact O-N 3.42Å; I370-S372 VanDerWaalsContact C-N 3.34Å; I370-S372 PolarHBondContact O-N 3.42Å; I370-L373 PolarHBondContact O-N 2.89Å; I370-I374 HydrophobicContact CG2-CD1 4.19Å; I370-I374 WeakPolarHBondContact O-CG1 3.35Å; I370-I374 PolarHBondContact O-N 3.23Å
371	M	94.8	Very high	91.9	Very high	27 Å²	27	42 Å²	42	13%	0.133	22%	0.22	C	C	.	.	H	α-helix	trans	-60.8	-43.2	177.5	-71.3	-58.8	-57.6	0	0	112	L128 P132 F367 N368 C369 L373 I374 Y375	L128-M371 HydrophobicContact CD2-CE 3.75Å; L128-M371 HydrophobicContact CD2-SD 4.16Å; P132-M371 HydrophobicContact CB-CB 3.71Å; P132-M371 HydrophobicContact CG-CB 3.55Å; P132-M371 HydrophobicContact CG-CG 4.39Å; F367-M371 HydrophobicContact CD1-CG 4.19Å; F367-M371 HydrophobicContact CE1-CG 3.53Å; F367-M371 HydrophobicContact CE2-CG 4.3Å; F367-M371 HydrophobicContact CZ-CG 3.61Å; F367-M371 HydrophobicContact CZ-SD 4.05Å; F367-M371 WeakPolarHBondContact O-CG 3.33Å; F367-M371 PolarHBondContact O-N 3.45Å; N368-M371 PolarHBondContact O-N 2.88Å; C369-M371 VanDerWaalsContact C-N 3.33Å; C369-M371 PolarHBondContact O-N 3.22Å; M371-L373 VanDerWaalsContact C-N 3.34Å; M371-L373 PolarHBondContact O-N 3.14Å; M371-I374 WeakPolarHBondContact O-CB 3.45Å; M371-I374 PolarHBondContact O-N 3.17Å; M371-I374 VanDerWaalsContact O-N 3.17Å; M371-I374 HydrophobicContact SD-CD1 4.22Å; M371-Y375 HydrophobicContact CE-CE2 4.1Å; M371-Y375 VanDerWaalsContact O-CD2 3.32Å; M371-Y375 WeakPolarHBondContact O-CD2 3.43Å; M371-Y375 PolarHBondContact O-N 3.06Å; M371-Y375 VanDerWaalsContact O-N 3.13Å
372	S	95.6	Very high	92.1	Very high	0 Å²	0	42 Å²	42	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-64.3	-39.3	178.7	-58.7	0	0	0	0	111.8	Q135 N368 C369 I370 I374 Y375 L376	Q135-S372 PolarHBondContact OE1-OG 2.73Å; Q135-S372 VanDerWaalsContact OE1-OG 3.05Å; N368-S372 WeakPolarHBondContact O-CB 3.34Å; N368-S372 PolarHBondContact O-N 2.9Å; N368-S372 PolarHBondContact O-OG 3.49Å; C369-S372 PolarHBondContact O-N 3.45Å; C369-S372 VanDerWaalsContact O-N 3.16Å; I370-S372 VanDerWaalsContact C-N 3.34Å; I370-S372 PolarHBondContact O-N 3.42Å; S372-I374 VanDerWaalsContact C-N 3.31Å; S372-I374 PolarHBondContact O-N 3.13Å; S372-Y375 PolarHBondContact O-N 3.5Å; S372-L376 WeakPolarHBondContact O-CG 3.27Å; S372-L376 PolarHBondContact O-N 3.49Å
373	L	96.6	Very high	92.3	Very high	56 Å²	56	43.6 Å²	43.6	29%	0.293	22%	0.224	S	C	.	.	H	α-helix	trans	-63.5	-34.8	174	-67.7	176.1	0	0	0	112.4	A166 C369 I370 M371 L376	A166-L373 HydrophobicContact CB-CD2 3.7Å; C369-L373 VanDerWaalsContact O-CG 3.31Å; C369-L373 WeakPolarHBondContact O-CG 3.19Å; C369-L373 PolarHBondContact O-N 3.46Å; I370-L373 PolarHBondContact O-N 2.89Å; M371-L373 VanDerWaalsContact C-N 3.34Å; M371-L373 PolarHBondContact O-N 3.14Å; L373-L376 HydrophobicContact CD2-CD1 3.86Å; L373-L376 WeakPolarHBondContact O-CB 3.31Å; L373-L376 PolarHBondContact O-N 3.13Å
374	I	95.8	Very high	92.5	Very high	90 Å²	90	43 Å²	43	46%	0.462	22%	0.221	S	C	.	.	H	α-helix	trans	-63.4	-46.2	173.3	-67.5	165.8	0	0	0	110	I370 M371 S372 L376 T377	I370-I374 HydrophobicContact CG2-CD1 4.19Å; I370-I374 WeakPolarHBondContact O-CG1 3.35Å; I370-I374 PolarHBondContact O-N 3.23Å; M371-I374 WeakPolarHBondContact O-CB 3.45Å; M371-I374 PolarHBondContact O-N 3.17Å; M371-I374 VanDerWaalsContact O-N 3.17Å; M371-I374 HydrophobicContact SD-CD1 4.22Å; S372-I374 VanDerWaalsContact C-N 3.31Å; S372-I374 PolarHBondContact O-N 3.13Å; I374-L376 VanDerWaalsContact C-N 3.26Å; I374-L376 PolarHBondContact O-N 3.42Å; I374-T377 WeakPolarHBondContact O-CB 3.39Å; I374-T377 WeakPolarHBondContact O-CG2 3.24Å; I374-T377 PolarHBondContact O-N 3Å; I374-T377 PolarHBondContact O-OG1 3.47Å
375	Y	94.8	Very high	92.7	Very high	25 Å²	25	43 Å²	43	10%	0.098	22%	0.221	C	C	.	.	H	α-helix	trans	-67.9	-22.3	178.1	-79	-76.3	0	0	0	114	L128 P132 T133 M371 S372 T377 V378 L384	L128-Y375 WeakPolarHBondContact O-CE2 3.14Å; L128-Y375 PolarHBondContact O-OH 3.35Å; P132-Y375 HydrophobicContact CB-CD2 3.63Å; P132-Y375 HydrophobicContact CB-CE2 3.88Å; T133-Y375 WeakPolarHBondContact OG1-CE1 3.47Å; M371-Y375 HydrophobicContact CE-CE2 4.1Å; M371-Y375 VanDerWaalsContact O-CD2 3.32Å; M371-Y375 WeakPolarHBondContact O-CD2 3.43Å; M371-Y375 PolarHBondContact O-N 3.06Å; M371-Y375 VanDerWaalsContact O-N 3.13Å; S372-Y375 PolarHBondContact O-N 3.5Å; Y375-T377 PolarHBondContact O-N 2.84Å; Y375-V378 HydrophobicContact CD1-CG2 4.42Å; Y375-V378 WeakPolarHBondContact O-CB 3.05Å; Y375-V378 PolarHBondContact O-N 3.32Å; Y375-V378 VanDerWaalsContact O-N 3.1Å; Y375-L384 HydrophobicContact CD1-CD2 3.58Å; Y375-L384 HydrophobicContact CG-CD2 4.22Å
376	L	94.4	Very high	92.8	Very high	10 Å²	10	43.3 Å²	43.3	5%	0.052	22%	0.222	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.9	-16.1	170	-69.5	179.5	0	0	0	113.5	A136 I140 R162 A165 A166 I169 S372 L373 I374 V378	A136-L376 HydrophobicContact CB-CD2 4.06Å; I140-L376 HydrophobicContact CD1-CD2 4.02Å; I140-L376 HydrophobicContact CG1-CD2 3.67Å; R162-L376 PolarHBondContact NH1-O 3.34Å; A165-L376 HydrophobicContact CB-CD1 4.34Å; A165-L376 HydrophobicContact CB-CD2 4Å; A166-L376 HydrophobicContact CB-CD1 3.75Å; I169-L376 HydrophobicContact CD1-CD1 3.87Å; I169-L376 HydrophobicContact CD1-CD2 4.31Å; I169-L376 HydrophobicContact CD1-CG 4.21Å; S372-L376 WeakPolarHBondContact O-CG 3.27Å; S372-L376 PolarHBondContact O-N 3.49Å; L373-L376 HydrophobicContact CD2-CD1 3.86Å; L373-L376 WeakPolarHBondContact O-CB 3.31Å; L373-L376 PolarHBondContact O-N 3.13Å; I374-L376 VanDerWaalsContact C-N 3.26Å; I374-L376 PolarHBondContact O-N 3.42Å; L376-V378 PolarHBondContact O-N 2.83Å
377	T	92.1	Very high	92.7	Very high	105 Å²	105	41.1 Å²	41.1	64%	0.644	21%	0.209	S	C	*	.	T	Hydrogen-bonded Turn	trans	-73.9	-17	174.4	67.9	0	0	0	0	112.9	I374 Y375 E379	I374-T377 WeakPolarHBondContact O-CB 3.39Å; I374-T377 WeakPolarHBondContact O-CG2 3.24Å; I374-T377 PolarHBondContact O-N 3Å; I374-T377 PolarHBondContact O-OG1 3.47Å; Y375-T377 PolarHBondContact O-N 2.84Å; T377-E379 PolarHBondContact O-N 3.36Å
378	V	91.8	Very high	92.7	Very high	28 Å²	28	38.8 Å²	38.8	17%	0.17	20%	0.199	C	C	.	.			trans	-73.7	119	176	-178.4	0	0	0	0	109.4	R162 Y375 L376 Q383 L384	R162-V378 PolarHBondContact NH1-O 2.76Å; R162-V378 PolarHBondContact NH2-O 3.49Å; Y375-V378 HydrophobicContact CD1-CG2 4.42Å; Y375-V378 WeakPolarHBondContact O-CB 3.05Å; Y375-V378 PolarHBondContact O-N 3.32Å; Y375-V378 VanDerWaalsContact O-N 3.1Å; L376-V378 PolarHBondContact O-N 2.83Å; V378-Q383 HydrophobicContact CG1-CB 4.29Å; V378-Q383 HydrophobicContact CG1-CG 4.45Å; V378-L384 HydrophobicContact CB-CD1 4.48Å; V378-L384 HydrophobicContact CB-CD2 3.77Å; V378-L384 HydrophobicContact CB-CG 4.1Å; V378-L384 HydrophobicContact CG1-CD2 4.01Å; V378-L384 HydrophobicContact CG1-CG 4.05Å; V378-L384 HydrophobicContact CG2-CD2 3.86Å
379	E	86.8	Confident	92.8	Very high	152 Å²	152	38.8 Å²	38.8	71%	0.71	20%	0.199	S	C	*	.	S	Bend	trans	-66.4	-41.4	-173.5	-65	-174.7	173.2	0	0	113	Y158 R162 T377	Y158-E379 HydrophobicContact CE2-CB 4.37Å; Y158-E379 HydrophobicContact CE2-CG 4.43Å; Y158-E379 WeakPolarHBondContact OH-CA 3.29Å; R162-E379 PolarHBondContact NH2-O 3.47Å; T377-E379 PolarHBondContact O-N 3.36Å
380	D	89.8	Confident	92.7	Very high	73 Å²	73	38.8 Å²	38.8	39%	0.39	20%	0.198	S	C	.	.			trans	-92.8	122.8	-177.8	-176.1	10.1	0	0	0	112.4	F382 Q383 L384	D380-F382 VanDerWaalsContact C-N 3.32Å; D380-F382 WeakPolarHBondContact OD1-CD2 3.31Å; D380-F382 PolarHBondContact OD1-N 2.89Å; D380-Q383 HydrophobicContact CB-CB 3.99Å; D380-Q383 WeakPolarHBondContact O-CB 3.16Å; D380-Q383 PolarHBondContact O-N 2.83Å; D380-Q383 PolarHBondContact OD2-N 2.92Å; D380-L384 PolarHBondContact O-N 3.31Å
381	V	91.3	Very high	92.5	Very high	20 Å²	20	34.6 Å²	34.6	12%	0.121	18%	0.177	C	C	.	.	H	α-helix	trans	-68.1	-32.9	176.1	-175.9	0	0	0	0	111.4	V60 V137 I140 Q383 L384 I385	V60-V381 HydrophobicContact CG1-CG1 4.2Å; V137-V381 HydrophobicContact CB-CG1 4.39Å; V137-V381 HydrophobicContact CG1-CG1 3.84Å; V137-V381 HydrophobicContact CG2-CG1 4.12Å; I140-V381 HydrophobicContact CB-CG2 4.27Å; I140-V381 HydrophobicContact CD1-CG2 4.05Å; I140-V381 HydrophobicContact CG2-CG2 3.54Å; V381-Q383 VanDerWaalsContact C-N 3.34Å; V381-L384 WeakPolarHBondContact O-CB 3.11Å; V381-L384 PolarHBondContact O-N 3.14Å; V381-I385 HydrophobicContact CG1-CD1 4.39Å; V381-I385 WeakPolarHBondContact O-CG1 3.18Å; V381-I385 PolarHBondContact O-N 2.72Å
382	F	90.6	Very high	92.4	Very high	21 Å²	21	33.7 Å²	33.7	9%	0.092	17%	0.172	C	C	.	.	H	α-helix	trans	-71.2	-32.6	178.9	-62.9	-69.1	0	0	0	111.6	V60 K63 I67 D380 L384 I385 N386	V60-F382 HydrophobicContact CG1-CE1 4.13Å; V60-F382 HydrophobicContact CG1-CZ 4.36Å; K63-F382 HydrophobicContact CB-CZ 4.1Å; K63-F382 HydrophobicContact CD-CE2 4.36Å; K63-F382 HydrophobicContact CD-CZ 4.28Å; K63-F382 HydrophobicContact CG-CE2 4.2Å; K63-F382 HydrophobicContact CG-CZ 3.85Å; I67-F382 HydrophobicContact CD1-CD2 4.48Å; I67-F382 HydrophobicContact CD1-CE2 4.08Å; I67-F382 HydrophobicContact CD1-CZ 4.44Å; D380-F382 VanDerWaalsContact C-N 3.32Å; D380-F382 WeakPolarHBondContact OD1-CD2 3.31Å; D380-F382 PolarHBondContact OD1-N 2.89Å; F382-L384 VanDerWaalsContact C-N 3.32Å; F382-L384 PolarHBondContact O-N 3.24Å; F382-I385 HydrophobicContact CD1-CD1 4.02Å; F382-I385 HydrophobicContact CE1-CD1 4.37Å; F382-I385 PolarHBondContact O-N 3.45Å; F382-N386 VanDerWaalsContact O-CG 3.27Å; F382-N386 PolarHBondContact O-N 3.45Å; F382-N386 PolarHBondContact O-OD1 2.93Å
383	Q	91.6	Very high	92.3	Very high	53 Å²	53	33.7 Å²	33.7	25%	0.248	17%	0.172	C	C	.	.	H	α-helix	trans	-59.7	-42.7	169.6	-167.1	179.8	18	0	0	111.8	V378 D380 V381 N386 Y387 N445	V378-Q383 HydrophobicContact CG1-CB 4.29Å; V378-Q383 HydrophobicContact CG1-CG 4.45Å; D380-Q383 HydrophobicContact CB-CB 3.99Å; D380-Q383 WeakPolarHBondContact O-CB 3.16Å; D380-Q383 PolarHBondContact O-N 2.83Å; D380-Q383 PolarHBondContact OD2-N 2.92Å; V381-Q383 VanDerWaalsContact C-N 3.34Å; Q383-N386 PolarHBondContact O-N 3.49Å; Q383-Y387 HydrophobicContact CG-CD2 4.27Å; Q383-Y387 HydrophobicContact CG-CE2 3.63Å; Q383-Y387 PolarHBondContact NE2-OH 2.89Å; Q383-Y387 VanDerWaalsContact O-CD2 3.26Å; Q383-Y387 WeakPolarHBondContact O-CD2 3.28Å; Q383-Y387 PolarHBondContact O-N 2.98Å; Q383-N445 PolarHBondContact NE2-OD1 2.92Å
384	L	92.9	Very high	92.2	Very high	0 Å²	0	35.6 Å²	35.6	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-61.3	-45.4	172.8	-65.5	174.9	0	0	0	111.4	T133 A136 V137 I140 Y375 V378 D380 V381 F382 N386 Y387 Y388	T133-L384 HydrophobicContact CG2-CB 3.67Å; T133-L384 HydrophobicContact CG2-CD2 3.94Å; T133-L384 HydrophobicContact CG2-CG 4.4Å; T133-L384 WeakPolarHBondContact CG2-O 3.45Å; A136-L384 HydrophobicContact CB-CD1 4.11Å; V137-L384 HydrophobicContact CG2-CB 3.52Å; V137-L384 HydrophobicContact CG2-CD1 4.13Å; V137-L384 HydrophobicContact CG2-CG 4.49Å; I140-L384 HydrophobicContact CD1-CD1 3.73Å; Y375-L384 HydrophobicContact CD1-CD2 3.58Å; Y375-L384 HydrophobicContact CG-CD2 4.22Å; V378-L384 HydrophobicContact CB-CD1 4.48Å; V378-L384 HydrophobicContact CB-CD2 3.77Å; V378-L384 HydrophobicContact CB-CG 4.1Å; V378-L384 HydrophobicContact CG1-CD2 4.01Å; V378-L384 HydrophobicContact CG1-CG 4.05Å; V378-L384 HydrophobicContact CG2-CD2 3.86Å; D380-L384 PolarHBondContact O-N 3.31Å; V381-L384 WeakPolarHBondContact O-CB 3.11Å; V381-L384 PolarHBondContact O-N 3.14Å; F382-L384 VanDerWaalsContact C-N 3.32Å; F382-L384 PolarHBondContact O-N 3.24Å; L384-N386 PolarHBondContact O-N 2.93Å; L384-Y387 HydrophobicContact CD2-CD2 4.43Å; L384-Y387 PolarHBondContact O-N 3.4Å; L384-Y388 WeakPolarHBondContact O-CB 3.48Å; L384-Y388 PolarHBondContact O-N 3.45Å
385	I	92.9	Very high	92.1	Very high	0 Å²	0	31.5 Å²	31.5	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-58.7	-38.4	176	-69.1	169.3	0	0	0	111.2	V60 V137 F240 V381 F382 S389	V60-I385 HydrophobicContact CG1-CD1 4.03Å; V137-I385 HydrophobicContact CG1-CD1 4.35Å; V137-I385 HydrophobicContact CG1-CG1 4.14Å; V137-I385 HydrophobicContact CG2-CG1 4.08Å; F240-I385 HydrophobicContact CB-CG2 3.9Å; F240-I385 HydrophobicContact CD1-CD1 4.22Å; F240-I385 HydrophobicContact CD1-CG1 4.23Å; F240-I385 HydrophobicContact CD2-CG1 4.35Å; F240-I385 HydrophobicContact CD2-CG2 4.43Å; F240-I385 HydrophobicContact CE1-CG1 4.45Å; F240-I385 HydrophobicContact CG-CG1 4.19Å; F240-I385 HydrophobicContact CG-CG2 4.15Å; V381-I385 HydrophobicContact CG1-CD1 4.39Å; V381-I385 WeakPolarHBondContact O-CG1 3.18Å; V381-I385 PolarHBondContact O-N 2.72Å; F382-I385 HydrophobicContact CD1-CD1 4.02Å; F382-I385 HydrophobicContact CE1-CD1 4.37Å; F382-I385 PolarHBondContact O-N 3.45Å; I385-S389 WeakPolarHBondContact O-CB 3.28Å; I385-S389 PolarHBondContact O-N 3.2Å; I385-S389 PolarHBondContact O-OG 3.3Å
386	N	91.4	Very high	92	Very high	9 Å²	9	30.3 Å²	30.3	5%	0.048	15%	0.152	C	C	.	.	H	α-helix	trans	-67.8	-45.9	177.6	-68.6	-4.1	0	0	0	111.9	Y236 F382 Q383 L384 Y388 S389 F390 D442	Y236-N386 HydrophobicContact CD2-CB 4.37Å; F382-N386 VanDerWaalsContact O-CG 3.27Å; F382-N386 PolarHBondContact O-N 3.45Å; F382-N386 PolarHBondContact O-OD1 2.93Å; Q383-N386 PolarHBondContact O-N 3.49Å; L384-N386 PolarHBondContact O-N 2.93Å; N386-Y388 VanDerWaalsContact C-N 3.33Å; N386-Y388 PolarHBondContact O-N 3.4Å; N386-S389 PolarHBondContact O-N 3.24Å; N386-F390 WeakPolarHBondContact O-CB 3.13Å; N386-F390 PolarHBondContact O-N 3.33Å; N386-D442 PolarHBondContact ND2-OD2 3.23Å
387	Y	88.9	Confident	92.1	Very high	27 Å²	27	30.3 Å²	30.3	11%	0.106	15%	0.154	C	C	.	.	H	α-helix	trans	-57.3	-46.4	175.6	-70.7	-44.9	0	0	0	112.4	Q383 L384 S391 N445 I448	Q383-Y387 HydrophobicContact CG-CD2 4.27Å; Q383-Y387 HydrophobicContact CG-CE2 3.63Å; Q383-Y387 PolarHBondContact NE2-OH 2.89Å; Q383-Y387 VanDerWaalsContact O-CD2 3.26Å; Q383-Y387 WeakPolarHBondContact O-CD2 3.28Å; Q383-Y387 PolarHBondContact O-N 2.98Å; L384-Y387 HydrophobicContact CD2-CD2 4.43Å; L384-Y387 PolarHBondContact O-N 3.4Å; Y387-S391 PolarHBondContact O-N 3.04Å; Y387-S391 PolarHBondContact O-OG 3.26Å; Y387-N445 HydrophobicContact CD1-CB 3.97Å; Y387-N445 HydrophobicContact CE1-CB 3.51Å; Y387-N445 PolarHBondContact OH-OD1 3.39Å; Y387-I448 HydrophobicContact CE1-CB 4.22Å; Y387-I448 HydrophobicContact CE1-CD1 4.43Å; Y387-I448 HydrophobicContact CE1-CG2 4.2Å
388	Y	92.6	Very high	92.3	Very high	13 Å²	13	27.1 Å²	27.1	5%	0.051	13%	0.133	C	C	.	.	H	α-helix	trans	-59.7	-54.3	174.8	167.8	-90.7	0	0	0	110.5	I130 F240 S243 L384 N386 F390 S391 Y392	I130-Y388 HydrophobicContact CB-CD2 4.44Å; I130-Y388 HydrophobicContact CG2-CD2 3.7Å; I130-Y388 HydrophobicContact CG2-CE2 3.42Å; I130-Y388 VanDerWaalsContact CG2-CE2 3.42Å; I130-Y388 WeakPolarHBondContact O-CD2 3.35Å; F240-Y388 AromaticContact CD2-CD1 3.58Å; F240-Y388 HydrophobicContact CD2-CD1 3.58Å; F240-Y388 AromaticContact CD2-CE1 3.7Å; F240-Y388 HydrophobicContact CD2-CE1 3.7Å; F240-Y388 HydrophobicContact CD2-CG 4.3Å; F240-Y388 HydrophobicContact CE2-CD1 4.05Å; F240-Y388 HydrophobicContact CE2-CE1 4.22Å; F240-Y388 HydrophobicContact CE2-CG 4.35Å; S243-Y388 WeakPolarHBondContact CB-OH 3.24Å; L384-Y388 WeakPolarHBondContact O-CB 3.48Å; L384-Y388 PolarHBondContact O-N 3.45Å; N386-Y388 VanDerWaalsContact C-N 3.33Å; N386-Y388 PolarHBondContact O-N 3.4Å; Y388-F390 PolarHBondContact O-N 3.03Å; Y388-S391 PolarHBondContact O-N 3.39Å; Y388-Y392 HydrophobicContact CE1-CD1 4.33Å; Y388-Y392 HydrophobicContact CE1-CG 4.18Å; Y388-Y392 HydrophobicContact CE2-CD2 4.33Å; Y388-Y392 HydrophobicContact CE2-CG 4.46Å; Y388-Y392 AromaticContact CZ-CG 3.89Å; Y388-Y392 WeakPolarHBondContact O-CB 3.29Å; Y388-Y392 PolarHBondContact O-N 2.9Å
389	S	92.9	Very high	92.4	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-63.7	-46	-170.5	-64.9	0	0	0	0	112.1	Y236 I385 N386 S391 Y392 W393	Y236-S389 VanDerWaalsContact CD2-CB 3.45Å; Y236-S389 VanDerWaalsContact CG-CB 3.45Å; I385-S389 WeakPolarHBondContact O-CB 3.28Å; I385-S389 PolarHBondContact O-N 3.2Å; I385-S389 PolarHBondContact O-OG 3.3Å; N386-S389 PolarHBondContact O-N 3.24Å; S389-S391 PolarHBondContact O-N 3.15Å; S389-Y392 PolarHBondContact O-N 2.97Å; S389-W393 WeakPolarHBondContact O-CB 3.11Å; S389-W393 PolarHBondContact O-N 2.91Å
390	F	92.8	Very high	92.8	Very high	14 Å²	14	18.5 Å²	18.5	6%	0.061	9%	0.091	C	C	.	.	H	α-helix	trans	-56.3	-52.9	178.6	178.1	-89.5	0	0	0	111.5	Y236 N386 Y388 F394 V435 L439 I450	Y236-F390 HydrophobicContact CE2-CB 4.29Å; Y236-F390 VanDerWaalsContact OH-CA 3.3Å; Y236-F390 WeakPolarHBondContact OH-CA 3.27Å; N386-F390 WeakPolarHBondContact O-CB 3.13Å; N386-F390 PolarHBondContact O-N 3.33Å; Y388-F390 PolarHBondContact O-N 3.03Å; F390-F394 WeakPolarHBondContact O-CB 3.36Å; F390-F394 PolarHBondContact O-N 3.43Å; F390-F394 VanDerWaalsContact O-N 3.14Å; F390-V435 HydrophobicContact CE2-CB 4.47Å; F390-V435 HydrophobicContact CE2-CG1 3.72Å; F390-V435 HydrophobicContact CZ-CG1 3.94Å; F390-L439 HydrophobicContact CE2-CD2 4.09Å; F390-L439 HydrophobicContact CE2-CG 4.28Å; F390-L439 HydrophobicContact CZ-CD2 4.18Å; F390-I450 HydrophobicContact CE1-CD1 4.39Å; F390-I450 HydrophobicContact CE1-CG1 3.79Å; F390-I450 HydrophobicContact CZ-CD1 3.94Å; F390-I450 HydrophobicContact CZ-CG1 3.85Å
391	S	92.7	Very high	93.1	Very high	4 Å²	4	16.7 Å²	16.7	3%	0.028	9%	0.086	C	C	.	.	H	α-helix	trans	-67.2	-44	-177.8	-57.4	0	0	0	0	111.4	Y387 Y388 S389 F395	Y387-S391 PolarHBondContact O-N 3.04Å; Y387-S391 PolarHBondContact O-OG 3.26Å; Y388-S391 PolarHBondContact O-N 3.39Å; S389-S391 PolarHBondContact O-N 3.15Å; S391-F395 WeakPolarHBondContact O-CD2 3.26Å; S391-F395 PolarHBondContact O-N 2.83Å
392	Y	92.8	Very high	93.2	Very high	7 Å²	7	15.7 Å²	15.7	3%	0.027	8%	0.08	C	C	.	.	H	α-helix	trans	-60.9	-54.4	-179.8	-176.8	-102.4	0	0	0	110.9	I130 D246 Y388 S389 F394 F395 M396	I130-Y392 HydrophobicContact CG2-CD2 4.1Å; D246-Y392 PolarHBondContact OD1-OH 2.69Å; D246-Y392 PolarHBondContact OD2-OH 2.57Å; Y388-Y392 HydrophobicContact CE1-CD1 4.33Å; Y388-Y392 HydrophobicContact CE1-CG 4.18Å; Y388-Y392 HydrophobicContact CE2-CD2 4.33Å; Y388-Y392 HydrophobicContact CE2-CG 4.46Å; Y388-Y392 AromaticContact CZ-CG 3.89Å; Y388-Y392 WeakPolarHBondContact O-CB 3.29Å; Y388-Y392 PolarHBondContact O-N 2.9Å; S389-Y392 PolarHBondContact O-N 2.97Å; Y392-F394 VanDerWaalsContact C-N 3.33Å; Y392-F394 PolarHBondContact O-N 3.08Å; Y392-F395 PolarHBondContact O-N 3.32Å; Y392-F395 VanDerWaalsContact O-N 3.14Å; Y392-M396 HydrophobicContact CD1-CG 3.87Å; Y392-M396 HydrophobicContact CD2-CG 4.32Å; Y392-M396 HydrophobicContact CE1-CE 4.37Å; Y392-M396 HydrophobicContact CE1-CG 3.6Å; Y392-M396 HydrophobicContact CE1-SD 4.21Å; Y392-M396 HydrophobicContact CE2-CG 4.08Å; Y392-M396 HydrophobicContact CE2-SD 3.87Å; Y392-M396 HydrophobicContact CG-CG 4.22Å; Y392-M396 VanDerWaalsContact O-CG 3.25Å; Y392-M396 WeakPolarHBondContact O-CG 3.47Å; Y392-M396 PolarHBondContact O-N 2.94Å; Y392-M396 WeakPolarHBondContact OH-CE 3.28Å
393	W	93.4	Very high	93.4	Very high	1 Å²	1	14.9 Å²	14.9	0%	0.004	8%	0.076	C	C	.	.	H	α-helix	trans	-66.7	-32.1	-176.6	-68.7	117	0	0	0	113.5	F85 L239 W245 S389 M396 G397 F427 L434	F85-W393 HydrophobicContact CD1-CH2 4.39Å; F85-W393 HydrophobicContact CD1-CZ3 4.35Å; F85-W393 HydrophobicContact CE1-CD2 4.2Å; F85-W393 AromaticContact CE1-CE3 3.64Å; F85-W393 HydrophobicContact CE1-CE3 3.64Å; F85-W393 AromaticContact CE1-CH2 3.77Å; F85-W393 HydrophobicContact CE1-CH2 3.77Å; F85-W393 HydrophobicContact CE1-CZ2 4.33Å; F85-W393 AromaticContact CE1-CZ3 3.38Å; F85-W393 HydrophobicContact CE1-CZ3 3.38Å; F85-W393 AromaticContact CZ-CE3 3.94Å; F85-W393 HydrophobicContact CZ-CE3 3.94Å; F85-W393 AromaticContact CZ-CZ3 3.91Å; F85-W393 HydrophobicContact CZ-CZ3 3.91Å; L239-W393 HydrophobicContact CB-CZ2 3.62Å; L239-W393 HydrophobicContact CD1-CZ2 3.97Å; L239-W393 HydrophobicContact CD2-CH2 4.38Å; L239-W393 HydrophobicContact CD2-CZ2 4.07Å; L239-W393 HydrophobicContact CG-CZ2 4.09Å; W245-W393 HydrophobicContact CZ2-CH2 4.46Å; W245-W393 HydrophobicContact CZ2-CZ3 4.4Å; S389-W393 WeakPolarHBondContact O-CB 3.11Å; S389-W393 PolarHBondContact O-N 2.91Å; W393-M396 HydrophobicContact CE3-CB 4.16Å; W393-M396 HydrophobicContact CE3-CG 4.39Å; W393-M396 HydrophobicContact CZ3-CB 4.47Å; W393-G397 PolarHBondContact O-N 3.19Å; W393-F427 HydrophobicContact CE3-CZ 4.26Å; W393-F427 HydrophobicContact CZ3-CE2 4.13Å; W393-F427 AromaticContact CZ3-CZ 3.94Å; W393-F427 HydrophobicContact CZ3-CZ 3.94Å; W393-L434 HydrophobicContact CB-CB 4.44Å; W393-L434 HydrophobicContact CB-CD1 4.46Å; W393-L434 HydrophobicContact CD2-CD1 4.15Å; W393-L434 HydrophobicContact CG-CD1 4.03Å
394	F	93.9	Very high	93.5	Very high	95 Å²	95	15 Å²	15	42%	0.417	8%	0.078	S	C	.	.	H	α-helix	trans	-56.9	-50.4	170.6	176	-101	0	0	0	111.6	F390 Y392 G397 L398 V435	F390-F394 WeakPolarHBondContact O-CB 3.36Å; F390-F394 PolarHBondContact O-N 3.43Å; F390-F394 VanDerWaalsContact O-N 3.14Å; Y392-F394 VanDerWaalsContact C-N 3.33Å; Y392-F394 PolarHBondContact O-N 3.08Å; F394-G397 PolarHBondContact O-N 3.09Å; F394-L398 HydrophobicContact CE1-CD2 4.46Å; F394-L398 WeakPolarHBondContact O-CB 3.4Å; F394-L398 PolarHBondContact O-N 3.3Å; F394-V435 HydrophobicContact CB-CG2 3.9Å; F394-V435 HydrophobicContact CD2-CG1 4.31Å; F394-V435 HydrophobicContact CD2-CG2 4.4Å
395	F	94.1	Very high	93.6	Very high	5 Å²	5	18.4 Å²	18.4	2%	0.022	9%	0.091	C	C	.	.	H	α-helix	trans	-75.9	-30.5	-178.1	-76.8	-62.4	0	0	0	114.3	I110 I121 R122 T125 I130 S391 Y392 L398 S399	I110-F395 HydrophobicContact CD1-CD1 4.1Å; I121-F395 HydrophobicContact CG2-CE1 4.44Å; I121-F395 HydrophobicContact CG2-CZ 4.03Å; R122-F395 VanDerWaalsContact CA-CE1 3.5Å; R122-F395 HydrophobicContact CB-CD1 3.79Å; R122-F395 HydrophobicContact CB-CE1 3.78Å; R122-F395 HydrophobicContact CB-CG 4.42Å; R122-F395 HydrophobicContact CB-CZ 4.44Å; R122-F395 HydrophobicContact CG-CD1 4.17Å; R122-F395 HydrophobicContact CG-CG 4.39Å; T125-F395 VanDerWaalsContact CB-CE2 3.46Å; T125-F395 HydrophobicContact CG2-CD2 4.48Å; T125-F395 HydrophobicContact CG2-CE2 3.69Å; T125-F395 WeakPolarHBondContact OG1-CE2 3.31Å; I130-F395 HydrophobicContact CD1-CD2 4.41Å; S391-F395 WeakPolarHBondContact O-CD2 3.26Å; S391-F395 PolarHBondContact O-N 2.83Å; Y392-F395 PolarHBondContact O-N 3.32Å; Y392-F395 VanDerWaalsContact O-N 3.14Å; F395-L398 HydrophobicContact CD1-CD2 4.12Å; F395-L398 HydrophobicContact CE1-CD2 4.39Å; F395-L398 PolarHBondContact O-N 3.3Å; F395-S399 WeakPolarHBondContact O-CB 3.17Å; F395-S399 PolarHBondContact O-N 3.29Å; F395-S399 PolarHBondContact O-OG 3.44Å
396	M	93.3	Very high	93.6	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-64.6	-45.4	171.1	-63.3	-58.2	-79.4	0	0	110	Y93 W245 D246 Y392 W393 L398 S399 V400 F427	Y93-M396 HydrophobicContact CD1-CE 4.39Å; Y93-M396 HydrophobicContact CD2-CE 4.24Å; Y93-M396 HydrophobicContact CE1-CE 3.73Å; Y93-M396 HydrophobicContact CE1-SD 4.24Å; Y93-M396 HydrophobicContact CE2-CE 3.56Å; Y93-M396 HydrophobicContact CE2-SD 4.3Å; Y93-M396 WeakPolarHBondContact OH-CE 3.39Å; Y93-M396 PolarHBondContact OH-SD 3.44Å; W245-M396 HydrophobicContact CH2-CE 3.16Å; W245-M396 HydrophobicContact CZ2-CE 3.58Å; W245-M396 HydrophobicContact CZ3-CE 3.81Å; D246-M396 HydrophobicContact CB-CE 4.05Å; Y392-M396 HydrophobicContact CD1-CG 3.87Å; Y392-M396 HydrophobicContact CD2-CG 4.32Å; Y392-M396 HydrophobicContact CE1-CE 4.37Å; Y392-M396 HydrophobicContact CE1-CG 3.6Å; Y392-M396 HydrophobicContact CE1-SD 4.21Å; Y392-M396 HydrophobicContact CE2-CG 4.08Å; Y392-M396 HydrophobicContact CE2-SD 3.87Å; Y392-M396 HydrophobicContact CG-CG 4.22Å; Y392-M396 VanDerWaalsContact O-CG 3.25Å; Y392-M396 WeakPolarHBondContact O-CG 3.47Å; Y392-M396 PolarHBondContact O-N 2.94Å; Y392-M396 WeakPolarHBondContact OH-CE 3.28Å; W393-M396 HydrophobicContact CE3-CB 4.16Å; W393-M396 HydrophobicContact CE3-CG 4.39Å; W393-M396 HydrophobicContact CZ3-CB 4.47Å; M396-L398 VanDerWaalsContact C-N 3.32Å; M396-L398 PolarHBondContact O-N 3Å; M396-S399 PolarHBondContact O-N 3.41Å; M396-V400 PolarHBondContact O-N 3.47Å; M396-V400 VanDerWaalsContact O-N 3.1Å; M396-F427 HydrophobicContact CB-CE1 4.32Å; M396-F427 HydrophobicContact CB-CZ 4.16Å
397	G	95.5	Very high	93.6	Very high	9 Å²	9	19.9 Å²	19.9	9%	0.093	10%	0.097	C	C	.	.	H	α-helix	trans	-58.4	-42.8	173.5	0	0	0	0	0	112.3	W393 F394 V400 A401	W393-G397 PolarHBondContact O-N 3.19Å; F394-G397 PolarHBondContact O-N 3.09Å; G397-V400 PolarHBondContact O-N 3.16Å; G397-A401 WeakPolarHBondContact O-CB 3.3Å; G397-A401 PolarHBondContact O-N 3.32Å
398	L	95.4	Very high	93.7	Very high	38 Å²	38	28.6 Å²	28.6	20%	0.199	13%	0.129	C	C	.	.	H	α-helix	trans	-64.4	-40	176.6	-171.8	59.8	0	0	0	112.4	I110 F114 I118 F394 F395 M396 V400 A401 G402	I110-L398 HydrophobicContact CD1-CD2 4.29Å; I110-L398 HydrophobicContact CD1-CG 4.45Å; F114-L398 HydrophobicContact CD2-CD1 4.29Å; F114-L398 HydrophobicContact CD2-CG 4.32Å; F114-L398 HydrophobicContact CE2-CD1 3.75Å; F114-L398 HydrophobicContact CE2-CG 3.98Å; F114-L398 WeakPolarHBondContact CE2-O 3.41Å; F114-L398 HydrophobicContact CZ-CD1 4Å; I118-L398 HydrophobicContact CG2-CD2 3.47Å; I118-L398 VanDerWaalsContact CG2-CD2 3.47Å; F394-L398 HydrophobicContact CE1-CD2 4.46Å; F394-L398 WeakPolarHBondContact O-CB 3.4Å; F394-L398 PolarHBondContact O-N 3.3Å; F395-L398 HydrophobicContact CD1-CD2 4.12Å; F395-L398 HydrophobicContact CE1-CD2 4.39Å; F395-L398 PolarHBondContact O-N 3.3Å; M396-L398 VanDerWaalsContact C-N 3.32Å; M396-L398 PolarHBondContact O-N 3Å; L398-V400 PolarHBondContact O-N 3.2Å; L398-A401 WeakPolarHBondContact O-CB 3.38Å; L398-A401 PolarHBondContact O-N 3.39Å; L398-G402 PolarHBondContact O-N 3.39Å
399	S	94.6	Very high	93.7	Very high	0 Å²	0	33.8 Å²	33.8	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-62.3	-43.7	177	-57.8	0	0	0	0	111.6	Y93 I110 F395 M396 G402 Q403	Y93-S399 WeakPolarHBondContact OH-CB 3.42Å; Y93-S399 PolarHBondContact OH-OG 3.43Å; I110-S399 WeakPolarHBondContact CD1-OG 3.41Å; F395-S399 WeakPolarHBondContact O-CB 3.17Å; F395-S399 PolarHBondContact O-N 3.29Å; F395-S399 PolarHBondContact O-OG 3.44Å; M396-S399 PolarHBondContact O-N 3.41Å; S399-G402 WeakPolarHBondContact O-CA 3.43Å; S399-G402 PolarHBondContact O-N 3.4Å; S399-G402 VanDerWaalsContact O-N 3.17Å; S399-Q403 PolarHBondContact O-N 2.93Å
400	V	95.4	Very high	93.7	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-71.3	-34.1	176.1	179.3	0	0	0	0	111.9	C92 Y93 M396 G397 L398 G402 Q403 I404 P424 F427	C92-V400 HydrophobicContact CB-CG1 4.06Å; C92-V400 HydrophobicContact CB-CG2 3.93Å; Y93-V400 HydrophobicContact CD2-CG2 4.03Å; Y93-V400 HydrophobicContact CE2-CG2 3.78Å; M396-V400 PolarHBondContact O-N 3.47Å; M396-V400 VanDerWaalsContact O-N 3.1Å; G397-V400 PolarHBondContact O-N 3.16Å; L398-V400 PolarHBondContact O-N 3.2Å; V400-G402 PolarHBondContact O-N 2.87Å; V400-Q403 WeakPolarHBondContact O-CA 3.42Å; V400-Q403 WeakPolarHBondContact O-CB 3.41Å; V400-Q403 PolarHBondContact O-N 3.37Å; V400-I404 PolarHBondContact O-N 3.41Å; V400-P424 HydrophobicContact CG1-CB 3.45Å; V400-P424 VanDerWaalsContact CG1-CB 3.45Å; V400-F427 HydrophobicContact CB-CD1 3.72Å; V400-F427 HydrophobicContact CB-CE1 4.12Å; V400-F427 HydrophobicContact CG1-CB 4.42Å; V400-F427 HydrophobicContact CG1-CD1 3.93Å; V400-F427 HydrophobicContact CG2-CD1 3.51Å; V400-F427 HydrophobicContact CG2-CE1 3.58Å; V400-F427 HydrophobicContact CG2-CG 4.43Å
401	A	96.1	Very high	93.5	Very high	34 Å²	34	40.3 Å²	40.3	28%	0.281	19%	0.189	S	C	.	.	H	α-helix	trans	-61	-36.3	169.4	0	0	0	0	0	111.2	G397 L398 Q403 I404 Y405	G397-A401 WeakPolarHBondContact O-CB 3.3Å; G397-A401 PolarHBondContact O-N 3.32Å; L398-A401 WeakPolarHBondContact O-CB 3.38Å; L398-A401 PolarHBondContact O-N 3.39Å; A401-Q403 VanDerWaalsContact C-N 3.31Å; A401-Q403 PolarHBondContact O-N 2.92Å; A401-I404 PolarHBondContact O-N 3.34Å; A401-Y405 WeakPolarHBondContact O-CB 3.48Å; A401-Y405 PolarHBondContact O-N 2.91Å
402	G	93.8	Very high	93.4	Very high	0 Å²	0	47.4 Å²	47.4	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-57.8	-39.9	170.2	0	0	0	0	0	112.8	L398 S399 V400 I404 Y405 L406	L398-G402 PolarHBondContact O-N 3.39Å; S399-G402 WeakPolarHBondContact O-CA 3.43Å; S399-G402 PolarHBondContact O-N 3.4Å; S399-G402 VanDerWaalsContact O-N 3.17Å; V400-G402 PolarHBondContact O-N 2.87Å; G402-I404 PolarHBondContact O-N 2.96Å; G402-Y405 PolarHBondContact O-N 3.33Å; G402-L406 WeakPolarHBondContact O-CB 3.38Å; G402-L406 VanDerWaalsContact O-CG 3.31Å; G402-L406 WeakPolarHBondContact O-CG 3.34Å; G402-L406 PolarHBondContact O-N 3.42Å
403	Q	93.7	Very high	93.2	Very high	4 Å²	4	49.6 Å²	49.6	2%	0.019	24%	0.235	C	C	.	.	H	α-helix	trans	-59.1	-46.8	173.5	-167.8	-167.5	-27.6	0	0	112.1	C92 E95 L96 S399 V400 A401 Y405 L406 R407	C92-Q403 PolarHBondContact O-OE1 3.34Å; E95-Q403 PolarHBondContact OE1-NE2 3.48Å; E95-Q403 PolarHBondContact OE2-NE2 3.4Å; L96-Q403 HydrophobicContact CD1-CB 4.22Å; L96-Q403 HydrophobicContact CD2-CB 3.7Å; L96-Q403 HydrophobicContact CD2-CG 3.91Å; L96-Q403 HydrophobicContact CG-CB 3.99Å; L96-Q403 HydrophobicContact CG-CG 4.05Å; S399-Q403 PolarHBondContact O-N 2.93Å; V400-Q403 WeakPolarHBondContact O-CA 3.42Å; V400-Q403 WeakPolarHBondContact O-CB 3.41Å; V400-Q403 PolarHBondContact O-N 3.37Å; A401-Q403 VanDerWaalsContact C-N 3.31Å; A401-Q403 PolarHBondContact O-N 2.92Å; Q403-Y405 VanDerWaalsContact C-N 3.35Å; Q403-L406 PolarHBondContact O-N 2.95Å; Q403-R407 WeakPolarHBondContact O-CG 3.45Å; Q403-R407 PolarHBondContact O-N 2.7Å; Q403-R407 VanDerWaalsContact O-N 3.07Å
404	I	94.8	Very high	93	Very high	55 Å²	55	54.6 Å²	54.6	28%	0.282	27%	0.268	S	S	.	.	H	α-helix	trans	-63.3	-44.7	178.1	-59.9	172.8	0	0	0	109.8	V400 A401 G402 R407 W408 P424 V425	V400-I404 PolarHBondContact O-N 3.41Å; A401-I404 PolarHBondContact O-N 3.34Å; G402-I404 PolarHBondContact O-N 2.96Å; I404-R407 WeakPolarHBondContact O-CB 3.41Å; I404-R407 PolarHBondContact O-N 3.06Å; I404-W408 PolarHBondContact O-N 3.07Å; I404-P424 HydrophobicContact CD1-CB 4.06Å; I404-P424 HydrophobicContact CG1-CB 3.88Å; I404-P424 HydrophobicContact CG1-CG 4.2Å; I404-V425 HydrophobicContact CD1-CG2 4.09Å
405	Y	94.6	Very high	92.9	Very high	72 Å²	72	51.9 Å²	51.9	28%	0.282	26%	0.255	S	S	.	.	H	α-helix	trans	-61.6	-44	177.1	171.4	-103.2	0	0	0	112.6	S113 A401 G402 Q403 R407 W408 K409	S113-Y405 WeakPolarHBondContact O-CE1 3.33Å; A401-Y405 WeakPolarHBondContact O-CB 3.48Å; A401-Y405 PolarHBondContact O-N 2.91Å; G402-Y405 PolarHBondContact O-N 3.33Å; Q403-Y405 VanDerWaalsContact C-N 3.35Å; Y405-R407 VanDerWaalsContact C-N 3.27Å; Y405-R407 PolarHBondContact O-N 2.68Å; Y405-W408 HydrophobicContact CD2-CE3 4.46Å; Y405-W408 HydrophobicContact CE2-CE3 4.49Å; Y405-W408 PolarHBondContact O-N 3.46Å; Y405-W408 VanDerWaalsContact O-N 3.1Å; Y405-K409 HydrophobicContact CE1-CB 4.45Å; Y405-K409 HydrophobicContact CE1-CD 3.73Å; Y405-K409 HydrophobicContact CE2-CB 4.5Å; Y405-K409 HydrophobicContact CE2-CD 4.14Å; Y405-K409 PolarHBondContact O-N 3.39Å; Y405-K409 WeakPolarHBondContact OH-CD 3.41Å; Y405-K409 PolarHBondContact OH-NZ 3.02Å
406	L	92.3	Very high	92.6	Very high	7 Å²	7	54.7 Å²	54.7	4%	0.037	27%	0.273	C	S	.	.	H	α-helix	trans	-64.8	-30.8	176.9	-75.1	176	0	0	0	112.4	I100 S113 G402 Q403 W408 Q410 R415	I100-L406 HydrophobicContact CD1-CD1 3.9Å; S113-L406 WeakPolarHBondContact OG-CD1 3.47Å; G402-L406 WeakPolarHBondContact O-CB 3.38Å; G402-L406 VanDerWaalsContact O-CG 3.31Å; G402-L406 WeakPolarHBondContact O-CG 3.34Å; G402-L406 PolarHBondContact O-N 3.42Å; Q403-L406 PolarHBondContact O-N 2.95Å; L406-W408 VanDerWaalsContact C-N 3.29Å; L406-W408 PolarHBondContact O-N 2.9Å; L406-Q410 CarbonylContact O-C 3.31Å; L406-Q410 VanDerWaalsContact O-C 3.31Å; L406-Q410 WeakPolarHBondContact O-CA 2.91Å; L406-Q410 PolarHBondContact O-N 3.3Å; L406-Q410 VanDerWaalsContact O-O 3.13Å; L406-R415 PolarHBondContact O-NH2 3.24Å
407	R	91.9	Very high	92.3	Very high	33 Å²	33	56.5 Å²	56.5	13%	0.125	28%	0.283	C	S	.	.	H	α-helix	trans	-64.4	-34.3	172.4	-75.5	177.3	173.1	-146.8	2.1	112.8	E95 Q403 I404 Y405 R415 L419	E95-R407 IonicContact OE1-CZ 3.48Å; E95-R407 VanDerWaalsContact OE1-CZ 3.24Å; E95-R407 IonicContact OE1-NE 3.83Å; E95-R407 PolarHBondContact OE1-NE 3.36Å; E95-R407 IonicContact OE1-NH2 2.86Å; E95-R407 PolarHBondContact OE1-NH2 3.17Å; E95-R407 IonicContact OE2-CZ 2.82Å; E95-R407 IonicContact OE2-NH2 3.14Å; E95-R407 PolarHBondContact OE2-NH2 3.36Å; Q403-R407 WeakPolarHBondContact O-CG 3.45Å; Q403-R407 PolarHBondContact O-N 2.7Å; Q403-R407 VanDerWaalsContact O-N 3.07Å; I404-R407 WeakPolarHBondContact O-CB 3.41Å; I404-R407 PolarHBondContact O-N 3.06Å; Y405-R407 VanDerWaalsContact C-N 3.27Å; Y405-R407 PolarHBondContact O-N 2.68Å; R407-R415 VanDerWaalsContact CA-NH2 3.33Å; R407-L419 VanDerWaalsContact CZ-O 3.3Å; R407-L419 PolarHBondContact NH1-O 3.29Å; R407-L419 PolarHBondContact NH2-O 2.87Å
408	W	91.5	Very high	92	Very high	209 Å²	209	63.2 Å²	63.2	79%	0.792	31%	0.309	S	S	*	.	H	α-helix	trans	-81.2	-46.4	177.7	-179	67	0	0	0	112.5	I404 Y405 L406	I404-W408 PolarHBondContact O-N 3.07Å; Y405-W408 HydrophobicContact CD2-CE3 4.46Å; Y405-W408 HydrophobicContact CE2-CE3 4.49Å; Y405-W408 PolarHBondContact O-N 3.46Å; Y405-W408 VanDerWaalsContact O-N 3.1Å; L406-W408 VanDerWaalsContact C-N 3.29Å; L406-W408 PolarHBondContact O-N 2.9Å
409	K	92.6	Very high	91.8	Very high	122 Å²	122	62.7 Å²	62.7	53%	0.53	31%	0.307	S	S	.	.	H	α-helix	trans	-78.9	-33.1	-175.2	-173.8	170.1	-178.7	-179.1	0	114.1	Y405	Y405-K409 HydrophobicContact CE1-CB 4.45Å; Y405-K409 HydrophobicContact CE1-CD 3.73Å; Y405-K409 HydrophobicContact CE2-CB 4.5Å; Y405-K409 HydrophobicContact CE2-CD 4.14Å; Y405-K409 PolarHBondContact O-N 3.39Å; Y405-K409 WeakPolarHBondContact OH-CD 3.41Å; Y405-K409 PolarHBondContact OH-NZ 3.02Å
410	Q	91.9	Very high	91.7	Very high	77 Å²	77	66.9 Å²	66.9	36%	0.36	33%	0.333	S	S	.	.			trans	-130.1	70.1	-179	-66.3	-179.2	-1.7	0	0	109.7	L406 D412 R413 R415	L406-Q410 CarbonylContact O-C 3.31Å; L406-Q410 VanDerWaalsContact O-C 3.31Å; L406-Q410 WeakPolarHBondContact O-CA 2.91Å; L406-Q410 PolarHBondContact O-N 3.3Å; L406-Q410 VanDerWaalsContact O-O 3.13Å; Q410-D412 VanDerWaalsContact C-N 3.3Å; Q410-D412 PolarHBondContact O-N 3.33Å; Q410-R413 HydrophobicContact CB-CB 4.36Å; Q410-R413 PolarHBondContact O-N 3.2Å; Q410-R413 VanDerWaalsContact OE1-NH1 3.15Å; Q410-R415 PolarHBondContact O-NH2 2.96Å
411	P	89.4	Confident	91.6	Very high	74 Å²	74	71.3 Å²	71.3	48%	0.481	36%	0.356	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.8	-37.9	-175.8	25	-33.1	0	0	0	112.2	R413 R415	P411-R413 VanDerWaalsContact C-N 3.3Å; P411-R413 PolarHBondContact O-N 3.01Å; P411-R415 PolarHBondContact O-NH1 3.36Å
412	D	90	Very high	91.5	Very high	154 Å²	154	76.2 Å²	76.2	82%	0.824	37%	0.371	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.7	-0.6	-173.1	-54.4	-46.2	0	0	0	114.7	Q410	Q410-D412 VanDerWaalsContact C-N 3.3Å; Q410-D412 PolarHBondContact O-N 3.33Å
413	R	89.8	Confident	91.5	Very high	53 Å²	53	80.2 Å²	80.2	20%	0.2	39%	0.387	C	S	.	.	S	Bend	trans	-60.9	131.4	176.7	-170.4	174.2	-175.3	143	0.6	109.4	T99 E112 Q410 P411 R415	T99-R413 HydrophobicContact CG2-CG 4.19Å; E112-R413 IonicContact OE1-CZ 2.74Å; E112-R413 IonicContact OE1-NH1 2.74Å; E112-R413 PolarHBondContact OE1-NH1 3.38Å; E112-R413 IonicContact OE1-NH2 3.82Å; E112-R413 PolarHBondContact OE1-NH2 3Å; E112-R413 VanDerWaalsContact OE1-NH2 3.14Å; Q410-R413 HydrophobicContact CB-CB 4.36Å; Q410-R413 PolarHBondContact O-N 3.2Å; Q410-R413 VanDerWaalsContact OE1-NH1 3.15Å; P411-R413 VanDerWaalsContact C-N 3.3Å; P411-R413 PolarHBondContact O-N 3.01Å; R413-R415 PolarHBondContact O-N 3.04Å
414	P	88.6	Confident	91.6	Very high	105 Å²	105	80 Å²	80	68%	0.682	39%	0.386	S	S	*	.			trans	-63.2	123.7	178.1	25.6	-33.4	0	0	0	109.6
415	R	90.8	Very high	91.6	Very high	39 Å²	39	80.6 Å²	80.6	15%	0.147	39%	0.392	C	S	.	.			trans	-121.9	96	178.1	-65.8	-177	-173.3	90.7	6.9	108.3	T99 L406 R407 Q410 P411 R413 L417 K418	T99-R415 HydrophobicContact CG2-CG 4.04Å; L406-R415 PolarHBondContact O-NH2 3.24Å; R407-R415 VanDerWaalsContact CA-NH2 3.33Å; Q410-R415 PolarHBondContact O-NH2 2.96Å; P411-R415 PolarHBondContact O-NH1 3.36Å; R413-R415 PolarHBondContact O-N 3.04Å; R415-L417 VanDerWaalsContact C-N 3.27Å; R415-L417 PolarHBondContact O-N 2.94Å; R415-K418 HydrophobicContact CB-CB 4.46Å
416	P	88	Confident	91.7	Very high	63 Å²	63	79.3 Å²	79.3	41%	0.409	39%	0.391	S	S	.	.	S	Bend	trans	-60	-39.1	-179	-24.7	34.3	0	0	0	112.6	E259	E259-P416 HydrophobicContact CB-CB 4.06Å; E259-P416 HydrophobicContact CG-CB 3.54Å; E259-P416 HydrophobicContact CG-CG 3.93Å; E259-P416 WeakPolarHBondContact OE1-CG 3.41Å
417	L	88.1	Confident	91.8	Very high	38 Å²	38	79 Å²	79	20%	0.199	39%	0.39	C	S	.	.	S	Bend	trans	-105.1	125.9	166.8	-172.8	74	0	0	0	108.8	A94 E95 T98 P263 R415	A94-L417 HydrophobicContact CB-CD2 3.74Å; E95-L417 HydrophobicContact CB-CD2 4.21Å; E95-L417 WeakPolarHBondContact CG-O 3.44Å; T98-L417 HydrophobicContact CG2-CB 4.48Å; T98-L417 WeakPolarHBondContact OG1-CB 3.21Å; P263-L417 HydrophobicContact CB-CD2 4.27Å; P263-L417 HydrophobicContact CG-CD1 4.26Å; P263-L417 HydrophobicContact CG-CD2 3.82Å; R415-L417 VanDerWaalsContact C-N 3.27Å; R415-L417 PolarHBondContact O-N 2.94Å
418	K	89.4	Confident	92	Very high	150 Å²	150	78.6 Å²	78.6	65%	0.652	39%	0.392	S	S	*	.			trans	-131.3	108	175.6	-173.5	179.9	179	179.7	0	109.9	R415	R415-K418 HydrophobicContact CB-CB 4.46Å
419	L	89.8	Confident	92.2	Very high	28 Å²	28	74.2 Å²	74.2	15%	0.147	38%	0.383	C	S	.	.			trans	-80.8	161.9	175.9	-62.4	173.7	0	0	0	111.5	L91 E95 R407 Y423	L91-L419 VanDerWaalsContact C-CD1 3.41Å; L91-L419 HydrophobicContact CB-CD1 3.77Å; L91-L419 WeakPolarHBondContact O-CD1 3.33Å; E95-L419 HydrophobicContact CB-CD1 4.49Å; E95-L419 WeakPolarHBondContact OE2-CB 3.47Å; E95-L419 PolarHBondContact OE2-N 3.47Å; R407-L419 VanDerWaalsContact CZ-O 3.3Å; R407-L419 PolarHBondContact NH1-O 3.29Å; R407-L419 PolarHBondContact NH2-O 2.87Å; L419-Y423 HydrophobicContact CB-CD2 4.3Å
420	T	93.2	Very high	92.3	Very high	88 Å²	88	70.7 Å²	70.7	54%	0.54	37%	0.373	S	S	.	.			trans	-66.2	149.7	167.5	58.5	0	0	0	0	109.5	F422 Y423 P424	T420-F422 PolarHBondContact O-N 2.9Å; T420-F422 VanDerWaalsContact O-N 3.08Å; T420-Y423 PolarHBondContact O-N 2.87Å; T420-Y423 VanDerWaalsContact OG1-CD2 3.27Å; T420-Y423 WeakPolarHBondContact OG1-CD2 3.26Å; T420-Y423 WeakPolarHBondContact OG1-CE2 3.39Å; T420-P424 VanDerWaalsContact O-CD 3.29Å; T420-P424 WeakPolarHBondContact O-CD 3.42Å
421	L	93.1	Very high	92.4	Very high	92 Å²	92	67.2 Å²	67.2	48%	0.482	36%	0.358	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.2	-15.6	179.1	-78.7	171.2	0	0	0	113.4	Y423 P424 V425	L421-Y423 PolarHBondContact O-N 3.42Å; L421-P424 HydrophobicContact CD2-CG 4.46Å; L421-P424 VanDerWaalsContact O-CD 3.31Å; L421-P424 WeakPolarHBondContact O-CD 3.31Å; L421-P424 WeakPolarHBondContact O-CG 3.4Å; L421-V425 WeakPolarHBondContact O-CB 3.32Å; L421-V425 WeakPolarHBondContact O-CG2 3.46Å; L421-V425 PolarHBondContact O-N 3.48Å
422	F	94.2	Very high	92.7	Very high	137 Å²	137	68.1 Å²	68.1	60%	0.601	36%	0.362	S	S	*	.	H	α-helix	trans	-54.5	-48.7	175.3	177.5	-101.7	0	0	0	112.3	T420 V425 V426	T420-F422 PolarHBondContact O-N 2.9Å; T420-F422 VanDerWaalsContact O-N 3.08Å; F422-V425 PolarHBondContact O-N 3.27Å; F422-V426 HydrophobicContact CD1-CG2 4.4Å; F422-V426 HydrophobicContact CD2-CG2 4.05Å; F422-V426 HydrophobicContact CE1-CG2 4.1Å; F422-V426 HydrophobicContact CE2-CG2 3.73Å; F422-V426 HydrophobicContact CG-CG2 4.38Å; F422-V426 HydrophobicContact CZ-CG2 3.76Å; F422-V426 WeakPolarHBondContact O-CB 3.33Å; F422-V426 VanDerWaalsContact O-CG2 3.24Å; F422-V426 WeakPolarHBondContact O-CG2 3.39Å; F422-V426 PolarHBondContact O-N 2.84Å
423	Y	94.2	Very high	92.9	Very high	84 Å²	84	64.3 Å²	64.3	33%	0.329	34%	0.338	S	S	.	.	H	α-helix	trans	-60	-55.5	-177.7	-66.1	-89.6	0	0	0	113.6	V88 L91 L419 T420 L421 V425 V426 F427	V88-Y423 HydrophobicContact CG1-CD1 4.2Å; V88-Y423 WeakPolarHBondContact CG1-O 3.02Å; V88-Y423 HydrophobicContact CG2-CD1 4.43Å; L91-Y423 HydrophobicContact CD1-CD1 4.42Å; L91-Y423 HydrophobicContact CD1-CE1 4.21Å; L419-Y423 HydrophobicContact CB-CD2 4.3Å; T420-Y423 PolarHBondContact O-N 2.87Å; T420-Y423 VanDerWaalsContact OG1-CD2 3.27Å; T420-Y423 WeakPolarHBondContact OG1-CD2 3.26Å; T420-Y423 WeakPolarHBondContact OG1-CE2 3.39Å; L421-Y423 PolarHBondContact O-N 3.42Å; Y423-V425 VanDerWaalsContact C-N 3.32Å; Y423-V425 PolarHBondContact O-N 3.02Å; Y423-V426 PolarHBondContact O-N 3.19Å; Y423-F427 WeakPolarHBondContact O-CB 3.31Å; Y423-F427 PolarHBondContact O-N 3.26Å
424	P	95.1	Very high	93	Very high	0 Å²	0	62 Å²	62	0%	0	33%	0.33	C	S	.	.	H	α-helix	trans	-66.8	-32.7	-179.2	26.4	-35.8	0	0	0	112.6	V400 I404 T420 L421 F427 C428	V400-P424 HydrophobicContact CG1-CB 3.45Å; V400-P424 VanDerWaalsContact CG1-CB 3.45Å; I404-P424 HydrophobicContact CD1-CB 4.06Å; I404-P424 HydrophobicContact CG1-CB 3.88Å; I404-P424 HydrophobicContact CG1-CG 4.2Å; T420-P424 VanDerWaalsContact O-CD 3.29Å; T420-P424 WeakPolarHBondContact O-CD 3.42Å; L421-P424 HydrophobicContact CD2-CG 4.46Å; L421-P424 VanDerWaalsContact O-CD 3.31Å; L421-P424 WeakPolarHBondContact O-CD 3.31Å; L421-P424 WeakPolarHBondContact O-CG 3.4Å; P424-F427 PolarHBondContact O-N 2.92Å; P424-C428 WeakPolarHBondContact O-CB 3.35Å; P424-C428 PolarHBondContact O-N 3.42Å; P424-C428 PolarHBondContact O-SG 3.49Å
425	V	95.6	Very high	93.2	Very high	67 Å²	67	58 Å²	58	41%	0.406	30%	0.303	S	S	.	.	H	α-helix	trans	-66.3	-47.4	175.9	171.6	0	0	0	0	111.1	I404 L421 F422 Y423 F427 C428 L429	I404-V425 HydrophobicContact CD1-CG2 4.09Å; L421-V425 WeakPolarHBondContact O-CB 3.32Å; L421-V425 WeakPolarHBondContact O-CG2 3.46Å; L421-V425 PolarHBondContact O-N 3.48Å; F422-V425 PolarHBondContact O-N 3.27Å; Y423-V425 VanDerWaalsContact C-N 3.32Å; Y423-V425 PolarHBondContact O-N 3.02Å; V425-F427 VanDerWaalsContact C-N 3.31Å; V425-F427 PolarHBondContact O-N 3.05Å; V425-C428 PolarHBondContact O-N 3.31Å; V425-L429 HydrophobicContact CG1-CD1 4.13Å; V425-L429 HydrophobicContact CG1-CG 4.48Å; V425-L429 WeakPolarHBondContact O-CG 3.49Å; V425-L429 PolarHBondContact O-N 3.31Å
426	V	95.6	Very high	93.3	Very high	46 Å²	46	58.3 Å²	58.3	28%	0.279	31%	0.314	S	S	.	.	H	α-helix	trans	-59.5	-44.7	176.2	169.6	0	0	0	0	110.6	F422 Y423 C428 L429 C430	F422-V426 HydrophobicContact CD1-CG2 4.4Å; F422-V426 HydrophobicContact CD2-CG2 4.05Å; F422-V426 HydrophobicContact CE1-CG2 4.1Å; F422-V426 HydrophobicContact CE2-CG2 3.73Å; F422-V426 HydrophobicContact CG-CG2 4.38Å; F422-V426 HydrophobicContact CZ-CG2 3.76Å; F422-V426 WeakPolarHBondContact O-CB 3.33Å; F422-V426 VanDerWaalsContact O-CG2 3.24Å; F422-V426 WeakPolarHBondContact O-CG2 3.39Å; F422-V426 PolarHBondContact O-N 2.84Å; Y423-V426 PolarHBondContact O-N 3.19Å; V426-C428 PolarHBondContact O-N 3.37Å; V426-L429 PolarHBondContact O-N 3.06Å; V426-C430 PolarHBondContact O-N 2.87Å; V426-C430 PolarHBondContact O-SG 2.89Å; V426-C430 VanDerWaalsContact O-SG 3.41Å
427	F	95.4	Very high	93.5	Very high	0 Å²	0	55.9 Å²	55.9	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-60.6	-46.2	177.2	-173.5	-96.8	0	0	0	112.4	F85 V88 W393 M396 V400 Y423 P424 V425 L429 C430 A431	F85-F427 HydrophobicContact CD2-CD2 4.02Å; F85-F427 HydrophobicContact CD2-CE2 4.29Å; F85-F427 AromaticContact CE1-CE2 3.99Å; F85-F427 HydrophobicContact CE1-CE2 3.99Å; F85-F427 AromaticContact CE2-CD2 3.34Å; F85-F427 HydrophobicContact CE2-CD2 3.34Å; F85-F427 AromaticContact CE2-CE2 3.49Å; F85-F427 HydrophobicContact CE2-CE2 3.49Å; F85-F427 VanDerWaalsContact CE2-CE2 3.49Å; F85-F427 HydrophobicContact CE2-CG 4.14Å; F85-F427 HydrophobicContact CE2-CZ 4.4Å; F85-F427 AromaticContact CZ-CD2 3.73Å; F85-F427 HydrophobicContact CZ-CD2 3.73Å; F85-F427 AromaticContact CZ-CE2 3.34Å; F85-F427 HydrophobicContact CZ-CE2 3.34Å; F85-F427 AromaticContact CZ-CZ 3.96Å; F85-F427 HydrophobicContact CZ-CZ 3.96Å; V88-F427 HydrophobicContact CG1-CB 4.04Å; W393-F427 HydrophobicContact CE3-CZ 4.26Å; W393-F427 HydrophobicContact CZ3-CE2 4.13Å; W393-F427 AromaticContact CZ3-CZ 3.94Å; W393-F427 HydrophobicContact CZ3-CZ 3.94Å; M396-F427 HydrophobicContact CB-CE1 4.32Å; M396-F427 HydrophobicContact CB-CZ 4.16Å; V400-F427 HydrophobicContact CB-CD1 3.72Å; V400-F427 HydrophobicContact CB-CE1 4.12Å; V400-F427 HydrophobicContact CG1-CB 4.42Å; V400-F427 HydrophobicContact CG1-CD1 3.93Å; V400-F427 HydrophobicContact CG2-CD1 3.51Å; V400-F427 HydrophobicContact CG2-CE1 3.58Å; V400-F427 HydrophobicContact CG2-CG 4.43Å; Y423-F427 WeakPolarHBondContact O-CB 3.31Å; Y423-F427 PolarHBondContact O-N 3.26Å; P424-F427 PolarHBondContact O-N 2.92Å; V425-F427 VanDerWaalsContact C-N 3.31Å; V425-F427 PolarHBondContact O-N 3.05Å; F427-L429 PolarHBondContact O-N 3.45Å; F427-C430 PolarHBondContact O-N 3.21Å; F427-A431 WeakPolarHBondContact O-CB 3.38Å; F427-A431 PolarHBondContact O-N 3.47Å
428	C	95.8	Very high	93.6	Very high	25 Å²	25	54.1 Å²	54.1	17%	0.169	29%	0.289	C	S	.	.	H	α-helix	trans	-62.1	-40.7	177	-73.2	0	0	0	0	112.2	P424 V425 V426 A431 V432	P424-C428 WeakPolarHBondContact O-CB 3.35Å; P424-C428 PolarHBondContact O-N 3.42Å; P424-C428 PolarHBondContact O-SG 3.49Å; V425-C428 PolarHBondContact O-N 3.31Å; V426-C428 PolarHBondContact O-N 3.37Å; C428-A431 PolarHBondContact O-N 3.49Å; C428-V432 VanDerWaalsContact O-CG2 3.29Å; C428-V432 WeakPolarHBondContact O-CG2 3.47Å; C428-V432 PolarHBondContact O-N 3.38Å
429	L	95.6	Very high	93.6	Very high	116 Å²	116	50.1 Å²	50.1	61%	0.607	27%	0.274	S	S	*	.	H	α-helix	trans	-62.9	-44.9	176.2	-71.2	173.6	0	0	0	111.7	V425 V426 F427 V432 F433	V425-L429 HydrophobicContact CG1-CD1 4.13Å; V425-L429 HydrophobicContact CG1-CG 4.48Å; V425-L429 WeakPolarHBondContact O-CG 3.49Å; V425-L429 PolarHBondContact O-N 3.31Å; V426-L429 PolarHBondContact O-N 3.06Å; F427-L429 PolarHBondContact O-N 3.45Å; L429-V432 PolarHBondContact O-N 3.2Å; L429-F433 PolarHBondContact O-N 3Å
430	C	94.4	Very high	93.6	Very high	48 Å²	48	55.1 Å²	55.1	32%	0.324	29%	0.292	S	S	.	.	H	α-helix	trans	-65.3	-39.2	175.2	-70.5	0	0	0	0	112.1	F85 V426 F427 V432 F433 L434	F85-C430 HydrophobicContact CD2-CB 3.55Å; F85-C430 HydrophobicContact CE2-CB 3.25Å; F85-C430 HydrophobicContact CZ-CB 4.16Å; V426-C430 PolarHBondContact O-N 2.87Å; V426-C430 PolarHBondContact O-SG 2.89Å; V426-C430 VanDerWaalsContact O-SG 3.41Å; F427-C430 PolarHBondContact O-N 3.21Å; C430-V432 VanDerWaalsContact C-N 3.33Å; C430-V432 PolarHBondContact O-N 2.9Å; C430-F433 WeakPolarHBondContact O-CB 3.26Å; C430-F433 PolarHBondContact O-N 3.15Å; C430-L434 WeakPolarHBondContact O-CB 3.4Å; C430-L434 WeakPolarHBondContact O-CG 3.43Å; C430-L434 PolarHBondContact O-N 3.29Å
431	A	94.6	Very high	93.2	Very high	4 Å²	4	53.1 Å²	53.1	3%	0.033	28%	0.282	C	S	.	.	H	α-helix	trans	-63.8	-39	174.4	0	0	0	0	0	111.7	F427 C428 L434 V435	F427-A431 WeakPolarHBondContact O-CB 3.38Å; F427-A431 PolarHBondContact O-N 3.47Å; C428-A431 PolarHBondContact O-N 3.49Å; A431-L434 PolarHBondContact O-N 3.24Å; A431-V435 WeakPolarHBondContact O-CG2 3.43Å; A431-V435 PolarHBondContact O-N 3.46Å
432	V	95	Very high	92.9	Very high	93 Å²	93	50 Å²	50	56%	0.564	27%	0.266	S	S	*	.	H	α-helix	trans	-62.9	-43.8	172.8	168.8	0	0	0	0	110.8	C428 L429 C430 L434 V435 A436	C428-V432 VanDerWaalsContact O-CG2 3.29Å; C428-V432 WeakPolarHBondContact O-CG2 3.47Å; C428-V432 PolarHBondContact O-N 3.38Å; L429-V432 PolarHBondContact O-N 3.2Å; C430-V432 VanDerWaalsContact C-N 3.33Å; C430-V432 PolarHBondContact O-N 2.9Å; V432-L434 VanDerWaalsContact C-N 3.34Å; V432-L434 PolarHBondContact O-N 3.24Å; V432-V435 PolarHBondContact O-N 2.87Å; V432-A436 WeakPolarHBondContact O-CB 3.18Å; V432-A436 PolarHBondContact O-N 3.38Å
433	F	94.1	Very high	92.6	Very high	75 Å²	75	46.6 Å²	46.6	33%	0.329	26%	0.256	S	S	.	.	H	α-helix	trans	-57.2	-48.3	173.7	171.1	-93.4	0	0	0	111.5	A232 L235 L429 C430 V435 A436 V437	A232-F433 HydrophobicContact CB-CE1 4.09Å; A232-F433 HydrophobicContact CB-CZ 4.31Å; L235-F433 HydrophobicContact CD1-CE1 4.09Å; L429-F433 PolarHBondContact O-N 3Å; C430-F433 WeakPolarHBondContact O-CB 3.26Å; C430-F433 PolarHBondContact O-N 3.15Å; F433-V435 PolarHBondContact O-N 2.67Å; F433-A436 PolarHBondContact O-N 3.46Å; F433-V437 HydrophobicContact CD2-CG2 3.65Å; F433-V437 HydrophobicContact CE2-CB 4.49Å; F433-V437 HydrophobicContact CE2-CG2 3.56Å; F433-V437 HydrophobicContact CG-CG2 4.33Å; F433-V437 HydrophobicContact CZ-CG2 4.15Å; F433-V437 WeakPolarHBondContact O-CB 3.45Å; F433-V437 WeakPolarHBondContact O-CG2 3.44Å; F433-V437 PolarHBondContact O-N 3.16Å
434	L	92.9	Very high	92.4	Very high	4 Å²	4	48.3 Å²	48.3	2%	0.021	27%	0.27	C	S	.	.	H	α-helix	trans	-63.9	-22.6	179.1	-72.8	175.7	0	0	0	113.3	F85 L235 Y236 L239 W393 C430 A431 V432 P438	F85-L434 HydrophobicContact CD1-CD1 4.42Å; F85-L434 HydrophobicContact CE1-CD1 3.62Å; F85-L434 HydrophobicContact CZ-CD1 3.81Å; L235-L434 HydrophobicContact CB-CD2 3.98Å; L235-L434 HydrophobicContact CD1-CD2 4.31Å; Y236-L434 HydrophobicContact CD1-CD2 4.01Å; Y236-L434 HydrophobicContact CE1-CB 4.05Å; Y236-L434 HydrophobicContact CE1-CD2 3.94Å; Y236-L434 VanDerWaalsContact CE1-O 3.25Å; Y236-L434 WeakPolarHBondContact CE1-O 3.44Å; Y236-L434 VanDerWaalsContact CZ-O 3.22Å; Y236-L434 PolarHBondContact OH-O 2.79Å; L239-L434 HydrophobicContact CD1-CD1 3.51Å; L239-L434 HydrophobicContact CD1-CD2 4.14Å; L239-L434 HydrophobicContact CD1-CG 4.5Å; W393-L434 HydrophobicContact CB-CB 4.44Å; W393-L434 HydrophobicContact CB-CD1 4.46Å; W393-L434 HydrophobicContact CD2-CD1 4.15Å; W393-L434 HydrophobicContact CG-CD1 4.03Å; C430-L434 WeakPolarHBondContact O-CB 3.4Å; C430-L434 WeakPolarHBondContact O-CG 3.43Å; C430-L434 PolarHBondContact O-N 3.29Å; A431-L434 PolarHBondContact O-N 3.24Å; V432-L434 VanDerWaalsContact C-N 3.34Å; V432-L434 PolarHBondContact O-N 3.24Å; L434-P438 WeakPolarHBondContact O-CD 3.41Å; L434-P438 WeakPolarHBondContact O-CG 3.46Å
435	V	92.9	Very high	92	Very high	22 Å²	22	49.2 Å²	49.2	13%	0.133	28%	0.275	C	S	.	.	H	α-helix	trans	-95.2	-41.7	176.4	172.7	0	0	0	0	111.3	F390 F394 A431 V432 F433 L439	F390-V435 HydrophobicContact CE2-CB 4.47Å; F390-V435 HydrophobicContact CE2-CG1 3.72Å; F390-V435 HydrophobicContact CZ-CG1 3.94Å; F394-V435 HydrophobicContact CB-CG2 3.9Å; F394-V435 HydrophobicContact CD2-CG1 4.31Å; F394-V435 HydrophobicContact CD2-CG2 4.4Å; A431-V435 WeakPolarHBondContact O-CG2 3.43Å; A431-V435 PolarHBondContact O-N 3.46Å; V432-V435 PolarHBondContact O-N 2.87Å; F433-V435 PolarHBondContact O-N 2.67Å; V435-L439 WeakPolarHBondContact O-CG 3.28Å
436	A	92.9	Very high	91.7	Very high	45 Å²	45	46.1 Å²	46.1	37%	0.372	26%	0.257	S	S	.	.	H	α-helix	trans	-74.2	-37.6	-172.6	0	0	0	0	0	112.9	V432 F433 L439	V432-A436 WeakPolarHBondContact O-CB 3.18Å; V432-A436 PolarHBondContact O-N 3.38Å; F433-A436 PolarHBondContact O-N 3.46Å; A436-L439 WeakPolarHBondContact O-CB 3.39Å; A436-L439 PolarHBondContact O-N 2.91Å
437	V	92	Very high	91.4	Very high	12 Å²	12	48.5 Å²	48.5	7%	0.073	27%	0.267	C	S	.	.	T	Hydrogen-bonded Turn	trans	-69.7	-44.1	-177.2	168	0	0	0	0	112.8	P228 A232 F433 L439 Y440 S441	P228-V437 WeakPolarHBondContact O-CG1 3.36Å; A232-V437 HydrophobicContact CB-CB 4.01Å; A232-V437 HydrophobicContact CB-CG1 3.49Å; A232-V437 VanDerWaalsContact CB-CG1 3.49Å; F433-V437 HydrophobicContact CD2-CG2 3.65Å; F433-V437 HydrophobicContact CE2-CB 4.49Å; F433-V437 HydrophobicContact CE2-CG2 3.56Å; F433-V437 HydrophobicContact CG-CG2 4.33Å; F433-V437 HydrophobicContact CZ-CG2 4.15Å; F433-V437 WeakPolarHBondContact O-CB 3.45Å; F433-V437 WeakPolarHBondContact O-CG2 3.44Å; F433-V437 PolarHBondContact O-N 3.16Å; V437-L439 PolarHBondContact O-N 2.98Å; V437-Y440 VanDerWaalsContact CA-CE1 3.46Å; V437-Y440 HydrophobicContact CB-CE1 4.11Å; V437-Y440 HydrophobicContact CG1-CE1 4.18Å; V437-Y440 HydrophobicContact CG1-CE2 4.31Å; V437-Y440 WeakPolarHBondContact CG1-OH 3.34Å; V437-Y440 HydrophobicContact CG2-CE1 4.1Å; V437-Y440 VanDerWaalsContact O-CD1 3.24Å; V437-Y440 WeakPolarHBondContact O-CD1 3.44Å; V437-Y440 WeakPolarHBondContact O-CE1 3.39Å; V437-Y440 PolarHBondContact O-N 3Å; V437-S441 PolarHBondContact O-N 2.97Å; V437-S441 VanDerWaalsContact O-N 3.14Å; V437-S441 PolarHBondContact O-OG 3.3Å
438	P	89.6	Confident	91.1	Very high	1 Å²	1	51.4 Å²	51.4	1%	0.006	28%	0.282	C	S	.	.	H	α-helix	trans	-66.2	-18.5	176	-30	43.6	0	0	0	114.2	A232 Y236 L434 Y440 S441 D442 S446	A232-P438 HydrophobicContact CB-CG 4.19Å; Y236-P438 HydrophobicContact CE1-CG 4.15Å; Y236-P438 HydrophobicContact CE2-CB 4.24Å; Y236-P438 HydrophobicContact CE2-CG 3.95Å; Y236-P438 WeakPolarHBondContact OH-CG 3.18Å; L434-P438 WeakPolarHBondContact O-CD 3.41Å; L434-P438 WeakPolarHBondContact O-CG 3.46Å; P438-Y440 PolarHBondContact O-N 3.16Å; P438-S441 PolarHBondContact O-N 2.99Å; P438-D442 CarbonylContact O-C 3.55Å; P438-D442 WeakPolarHBondContact O-CA 3.31Å; P438-D442 PolarHBondContact O-N 2.93Å; P438-S446 PolarHBondContact O-OG 3.09Å
439	L	89.8	Confident	90.7	Very high	66 Å²	66	50.3 Å²	50.3	35%	0.346	28%	0.275	S	S	.	.	H	α-helix	trans	-61.6	-29.1	174.6	-74	170.5	0	0	0	113.7	F390 V435 A436 V437 T443 I450	F390-L439 HydrophobicContact CE2-CD2 4.09Å; F390-L439 HydrophobicContact CE2-CG 4.28Å; F390-L439 HydrophobicContact CZ-CD2 4.18Å; V435-L439 WeakPolarHBondContact O-CG 3.28Å; A436-L439 WeakPolarHBondContact O-CB 3.39Å; A436-L439 PolarHBondContact O-N 2.91Å; V437-L439 PolarHBondContact O-N 2.98Å; L439-T443 WeakPolarHBondContact O-CA 3.33Å; L439-T443 WeakPolarHBondContact O-CB 3.44Å; L439-T443 WeakPolarHBondContact O-CG2 3.27Å; L439-T443 PolarHBondContact O-OG1 3.49Å; L439-I450 HydrophobicContact CD2-CD1 3.71Å
440	Y	88.4	Confident	90.5	Very high	132 Å²	132	47.5 Å²	47.5	52%	0.518	26%	0.26	S	S	.	.	H	α-helix	trans	-101.2	-32.3	173.6	63.2	-100.4	0	0	0	112.4	V437 P438 T443	V437-Y440 VanDerWaalsContact CA-CE1 3.46Å; V437-Y440 HydrophobicContact CB-CE1 4.11Å; V437-Y440 HydrophobicContact CG1-CE1 4.18Å; V437-Y440 HydrophobicContact CG1-CE2 4.31Å; V437-Y440 WeakPolarHBondContact CG1-OH 3.34Å; V437-Y440 HydrophobicContact CG2-CE1 4.1Å; V437-Y440 VanDerWaalsContact O-CD1 3.24Å; V437-Y440 WeakPolarHBondContact O-CD1 3.44Å; V437-Y440 WeakPolarHBondContact O-CE1 3.39Å; V437-Y440 PolarHBondContact O-N 3Å; P438-Y440 PolarHBondContact O-N 3.16Å; Y440-T443 PolarHBondContact O-OG1 3.15Å
441	S	85.7	Confident	90.4	Very high	46 Å²	46	48 Å²	48	32%	0.322	27%	0.268	S	S	.	.	H	α-helix	trans	-77.7	-38.1	-176.3	-46.2	0	0	0	0	112.4	G229 V437 P438	G229-S441 WeakPolarHBondContact CA-OG 3.43Å; V437-S441 PolarHBondContact O-N 2.97Å; V437-S441 VanDerWaalsContact O-N 3.14Å; V437-S441 PolarHBondContact O-OG 3.3Å; P438-S441 PolarHBondContact O-N 2.99Å
442	D	86.6	Confident	90.2	Very high	27 Å²	27	49.8 Å²	49.8	14%	0.144	28%	0.276	C	S	.	.	T	Hydrogen-bonded Turn	trans	-133.3	60.3	178.9	-169.3	6.1	0	0	0	109.9	L233 N386 P438 L444 N445 S446	L233-D442 HydrophobicContact CD2-CB 4.31Å; N386-D442 PolarHBondContact ND2-OD2 3.23Å; P438-D442 CarbonylContact O-C 3.55Å; P438-D442 WeakPolarHBondContact O-CA 3.31Å; P438-D442 PolarHBondContact O-N 2.93Å; D442-L444 PolarHBondContact O-N 2.93Å; D442-N445 PolarHBondContact O-N 3.25Å; D442-N445 WeakPolarHBondContact OD1-CB 3.4Å; D442-N445 VanDerWaalsContact OD1-CG 3.3Å; D442-N445 PolarHBondContact OD1-ND2 2.93Å; D442-N445 WeakPolarHBondContact OD2-CB 3.46Å; D442-N445 PolarHBondContact OD2-ND2 3.49Å; D442-S446 WeakPolarHBondContact O-CB 3.28Å; D442-S446 PolarHBondContact O-N 3.32Å; D442-S446 VanDerWaalsContact O-N 3.11Å; D442-S446 PolarHBondContact O-OG 3.27Å
443	T	89.2	Confident	90.1	Very high	66 Å²	66	46.1 Å²	46.1	41%	0.405	26%	0.256	S	S	.	.	H	α-helix	trans	-59.2	-46.1	-168.5	-55.2	0	0	0	0	111.9	L439 Y440 S446 L447	L439-T443 WeakPolarHBondContact O-CA 3.33Å; L439-T443 WeakPolarHBondContact O-CB 3.44Å; L439-T443 WeakPolarHBondContact O-CG2 3.27Å; L439-T443 PolarHBondContact O-OG1 3.49Å; Y440-T443 PolarHBondContact O-OG1 3.15Å; T443-S446 PolarHBondContact O-N 3.47Å; T443-L447 HydrophobicContact CG2-CD1 3.75Å; T443-L447 HydrophobicContact CG2-CG 4.19Å; T443-L447 WeakPolarHBondContact O-CB 3.3Å; T443-L447 VanDerWaalsContact O-CG 3.23Å; T443-L447 WeakPolarHBondContact O-CG 3.14Å; T443-L447 PolarHBondContact O-N 3.27Å
444	L	89	Confident	90	Very high	119 Å²	119	47.6 Å²	47.6	62%	0.623	27%	0.266	S	S	*	.	H	α-helix	trans	-64.1	-48.3	-174.9	-178.6	63.3	0	0	0	111.1	D442 S446 L447 I448	D442-L444 PolarHBondContact O-N 2.93Å; L444-S446 VanDerWaalsContact C-N 3.33Å; L444-S446 PolarHBondContact O-N 3.25Å; L444-L447 PolarHBondContact O-N 3.45Å; L444-I448 HydrophobicContact CD1-CD1 4.25Å; L444-I448 HydrophobicContact CG-CD1 4.05Å; L444-I448 VanDerWaalsContact O-CG1 3.29Å; L444-I448 WeakPolarHBondContact O-CG1 3.46Å; L444-I448 PolarHBondContact O-N 3.12Å
445	N	86.9	Confident	90.1	Very high	19 Å²	19	49.7 Å²	49.7	10%	0.102	28%	0.282	C	S	.	.	H	α-helix	trans	-67.1	-39	-177.3	-65.2	-31.1	0	0	0	111.5	Q383 Y387 D442 I448 G449	Q383-N445 PolarHBondContact NE2-OD1 2.92Å; Y387-N445 HydrophobicContact CD1-CB 3.97Å; Y387-N445 HydrophobicContact CE1-CB 3.51Å; Y387-N445 PolarHBondContact OH-OD1 3.39Å; D442-N445 PolarHBondContact O-N 3.25Å; D442-N445 WeakPolarHBondContact OD1-CB 3.4Å; D442-N445 VanDerWaalsContact OD1-CG 3.3Å; D442-N445 PolarHBondContact OD1-ND2 2.93Å; D442-N445 WeakPolarHBondContact OD2-CB 3.46Å; D442-N445 PolarHBondContact OD2-ND2 3.49Å; N445-I448 PolarHBondContact O-N 3.34Å; N445-G449 PolarHBondContact O-N 3.45Å; N445-G449 VanDerWaalsContact O-N 3.08Å
446	S	88.1	Confident	90	Very high	3 Å²	3	48.7 Å²	48.7	2%	0.021	28%	0.275	C	S	.	.	H	α-helix	trans	-64.2	-43.1	176	-56.5	0	0	0	0	112.1	P438 D442 T443 L444 G449 I450	P438-S446 PolarHBondContact O-OG 3.09Å; D442-S446 WeakPolarHBondContact O-CB 3.28Å; D442-S446 PolarHBondContact O-N 3.32Å; D442-S446 VanDerWaalsContact O-N 3.11Å; D442-S446 PolarHBondContact O-OG 3.27Å; T443-S446 PolarHBondContact O-N 3.47Å; L444-S446 VanDerWaalsContact C-N 3.33Å; L444-S446 PolarHBondContact O-N 3.25Å; S446-G449 PolarHBondContact O-N 3.04Å; S446-I450 WeakPolarHBondContact O-CG1 3.44Å; S446-I450 PolarHBondContact O-N 3.45Å
447	L	90.5	Very high	90	Very high	95 Å²	95	48.4 Å²	48.4	50%	0.497	27%	0.269	S	S	.	.	H	α-helix	trans	-65.2	-38.2	177.2	-74.9	177.1	0	0	0	112.5	T443 L444 G449 I450 A451	T443-L447 HydrophobicContact CG2-CD1 3.75Å; T443-L447 HydrophobicContact CG2-CG 4.19Å; T443-L447 WeakPolarHBondContact O-CB 3.3Å; T443-L447 VanDerWaalsContact O-CG 3.23Å; T443-L447 WeakPolarHBondContact O-CG 3.14Å; T443-L447 PolarHBondContact O-N 3.27Å; L444-L447 PolarHBondContact O-N 3.45Å; L447-G449 VanDerWaalsContact C-N 3.34Å; L447-I450 PolarHBondContact O-N 3.31Å; L447-A451 VanDerWaalsContact O-CB 3.31Å; L447-A451 WeakPolarHBondContact O-CB 3.34Å; L447-A451 PolarHBondContact O-N 3.42Å
448	I	88.4	Confident	90	Very high	61 Å²	61	51.3 Å²	51.3	31%	0.313	29%	0.288	S	S	.	.	H	α-helix	trans	-61.1	-45.8	173.7	-68.8	165.1	0	0	0	110	Y387 L444 N445 I450 A451 I452	Y387-I448 HydrophobicContact CE1-CB 4.22Å; Y387-I448 HydrophobicContact CE1-CD1 4.43Å; Y387-I448 HydrophobicContact CE1-CG2 4.2Å; L444-I448 HydrophobicContact CD1-CD1 4.25Å; L444-I448 HydrophobicContact CG-CD1 4.05Å; L444-I448 VanDerWaalsContact O-CG1 3.29Å; L444-I448 WeakPolarHBondContact O-CG1 3.46Å; L444-I448 PolarHBondContact O-N 3.12Å; N445-I448 PolarHBondContact O-N 3.34Å; I448-I450 PolarHBondContact O-N 3.28Å; I448-A451 PolarHBondContact O-N 3.39Å; I448-I452 HydrophobicContact CG2-CD1 3.82Å; I448-I452 HydrophobicContact CG2-CG1 4.46Å; I448-I452 WeakPolarHBondContact O-CG1 3.44Å; I448-I452 PolarHBondContact O-N 3.21Å
449	G	87.5	Confident	90	Very high	3 Å²	3	54 Å²	54	3%	0.031	30%	0.304	C	S	.	.	H	α-helix	trans	-58	-45.7	175.9	0	0	0	0	0	112.9	N445 S446 L447 I452 A453	N445-G449 PolarHBondContact O-N 3.45Å; N445-G449 VanDerWaalsContact O-N 3.08Å; S446-G449 PolarHBondContact O-N 3.04Å; L447-G449 VanDerWaalsContact C-N 3.34Å; G449-I452 PolarHBondContact O-N 3.42Å; G449-A453 PolarHBondContact O-N 3.37Å
450	I	91.6	Very high	89.9	Confident	57 Å²	57	52.1 Å²	52.1	29%	0.292	29%	0.293	S	S	.	.	H	α-helix	trans	-62.6	-45.5	175.3	-67.9	168.6	0	0	0	111.1	F390 L439 S446 L447 I448 I452 A453 L454	F390-I450 HydrophobicContact CE1-CD1 4.39Å; F390-I450 HydrophobicContact CE1-CG1 3.79Å; F390-I450 HydrophobicContact CZ-CD1 3.94Å; F390-I450 HydrophobicContact CZ-CG1 3.85Å; L439-I450 HydrophobicContact CD2-CD1 3.71Å; S446-I450 WeakPolarHBondContact O-CG1 3.44Å; S446-I450 PolarHBondContact O-N 3.45Å; L447-I450 PolarHBondContact O-N 3.31Å; I448-I450 PolarHBondContact O-N 3.28Å; I450-I452 VanDerWaalsContact C-N 3.33Å; I450-I452 PolarHBondContact O-N 3.48Å; I450-A453 PolarHBondContact O-N 3.41Å; I450-L454 HydrophobicContact CG2-CD1 3.69Å; I450-L454 HydrophobicContact CG2-CG 4.09Å; I450-L454 WeakPolarHBondContact O-CB 3.26Å; I450-L454 VanDerWaalsContact O-CG 3.32Å; I450-L454 WeakPolarHBondContact O-CG 3.29Å; I450-L454 PolarHBondContact O-N 3.16Å
451	A	92.8	Very high	89.9	Confident	58 Å²	58	50.3 Å²	50.3	48%	0.479	29%	0.288	S	S	.	.	H	α-helix	trans	-61.7	-42.1	-179.2	0	0	0	0	0	111.6	L447 I448 L454 S455	L447-A451 VanDerWaalsContact O-CB 3.31Å; L447-A451 WeakPolarHBondContact O-CB 3.34Å; L447-A451 PolarHBondContact O-N 3.42Å; I448-A451 PolarHBondContact O-N 3.39Å; A451-L454 PolarHBondContact O-N 3.39Å; A451-S455 WeakPolarHBondContact O-CB 3.29Å; A451-S455 PolarHBondContact O-N 2.89Å
452	I	91.1	Very high	89.8	Confident	42 Å²	42	51.4 Å²	51.4	22%	0.215	29%	0.29	C	S	.	.	H	α-helix	trans	-66	-42.5	175.5	-65.8	167.8	0	0	0	110.6	W124 L128 I129 I448 G449 I450 L454 S455	W124-I452 PolarHBondContact NE1-O 3.27Å; L128-I452 HydrophobicContact CB-CG2 3.89Å; L128-I452 HydrophobicContact CD1-CG2 3.9Å; I129-I452 HydrophobicContact CD1-CB 3.76Å; I129-I452 HydrophobicContact CD1-CD1 4.08Å; I129-I452 HydrophobicContact CD1-CG2 3.65Å; I129-I452 HydrophobicContact CG1-CB 4.29Å; I129-I452 HydrophobicContact CG1-CD1 4.23Å; I129-I452 HydrophobicContact CG1-CG2 3.68Å; I448-I452 HydrophobicContact CG2-CD1 3.82Å; I448-I452 HydrophobicContact CG2-CG1 4.46Å; I448-I452 WeakPolarHBondContact O-CG1 3.44Å; I448-I452 PolarHBondContact O-N 3.21Å; G449-I452 PolarHBondContact O-N 3.42Å; I450-I452 VanDerWaalsContact C-N 3.33Å; I450-I452 PolarHBondContact O-N 3.48Å; I452-L454 PolarHBondContact O-N 3.46Å; I452-S455 WeakPolarHBondContact O-CB 3.47Å; I452-S455 PolarHBondContact O-N 2.97Å; I452-S455 PolarHBondContact O-OG 3.46Å
453	A	91.2	Very high	89.4	Confident	16 Å²	16	51.2 Å²	51.2	13%	0.132	30%	0.295	C	S	.	.	H	α-helix	trans	-60.9	-45.3	175	0	0	0	0	0	111.7	I121 G449 I450 S455 G456	I121-A453 HydrophobicContact CG2-CB 4.42Å; G449-A453 PolarHBondContact O-N 3.37Å; I450-A453 PolarHBondContact O-N 3.41Å; A453-S455 VanDerWaalsContact C-N 3.31Å; A453-S455 PolarHBondContact O-N 3.23Å; A453-G456 PolarHBondContact O-N 3.41Å; A453-G456 VanDerWaalsContact O-N 3.14Å
454	L	93.3	Very high	89	Confident	105 Å²	105	49.8 Å²	49.8	55%	0.55	29%	0.285	S	S	.	.	H	α-helix	trans	-69.3	-25.6	178.1	-69.5	179	0	0	0	113.3	I450 A451 I452 G456 V457 P458	I450-L454 HydrophobicContact CG2-CD1 3.69Å; I450-L454 HydrophobicContact CG2-CG 4.09Å; I450-L454 WeakPolarHBondContact O-CB 3.26Å; I450-L454 VanDerWaalsContact O-CG 3.32Å; I450-L454 WeakPolarHBondContact O-CG 3.29Å; I450-L454 PolarHBondContact O-N 3.16Å; A451-L454 PolarHBondContact O-N 3.39Å; I452-L454 PolarHBondContact O-N 3.46Å; L454-G456 PolarHBondContact O-N 3.36Å; L454-G456 VanDerWaalsContact O-N 3.14Å; L454-V457 HydrophobicContact CD2-CG2 4.32Å; L454-V457 VanDerWaalsContact O-CB 3.3Å; L454-V457 WeakPolarHBondContact O-CB 3.3Å; L454-V457 WeakPolarHBondContact O-CG2 3.37Å; L454-V457 PolarHBondContact O-N 2.93Å; L454-P458 WeakPolarHBondContact O-CD 3.19Å
455	S	94.6	Very high	88.7	Confident	49 Å²	49	51.7 Å²	51.7	34%	0.343	29%	0.285	S	S	.	.	H	α-helix	trans	-60.7	-20.7	171.8	79.6	0	0	0	0	112.5	W124 A451 I452 A453 V457 P458 V459	W124-S455 PolarHBondContact NE1-OG 3.46Å; W124-S455 VanDerWaalsContact NE1-OG 3.13Å; A451-S455 WeakPolarHBondContact O-CB 3.29Å; A451-S455 PolarHBondContact O-N 2.89Å; I452-S455 WeakPolarHBondContact O-CB 3.47Å; I452-S455 PolarHBondContact O-N 2.97Å; I452-S455 PolarHBondContact O-OG 3.46Å; A453-S455 VanDerWaalsContact C-N 3.31Å; A453-S455 PolarHBondContact O-N 3.23Å; S455-V457 VanDerWaalsContact C-N 3.29Å; S455-V457 PolarHBondContact O-N 3.08Å; S455-P458 VanDerWaalsContact O-CD 3.27Å; S455-P458 WeakPolarHBondContact O-CD 3.21Å; S455-P458 VanDerWaalsContact O-CG 3.28Å; S455-P458 WeakPolarHBondContact O-CG 3.4Å; S455-V459 WeakPolarHBondContact O-CG2 3.29Å
456	G	91.4	Very high	88.3	Confident	0 Å²	0	53 Å²	53	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-69.1	-24.8	172.5	0	0	0	0	0	113.4	F120 W124 A453 L454 V459 Y460	F120-G456 WeakPolarHBondContact CE1-O 3.23Å; W124-G456 VanDerWaalsContact CD1-CA 3.44Å; A453-G456 PolarHBondContact O-N 3.41Å; A453-G456 VanDerWaalsContact O-N 3.14Å; L454-G456 PolarHBondContact O-N 3.36Å; L454-G456 VanDerWaalsContact O-N 3.14Å; G456-V459 PolarHBondContact O-N 2.99Å; G456-Y460 WeakPolarHBondContact O-CB 3.37Å; G456-Y460 PolarHBondContact O-N 3.23Å
457	V	92.7	Very high	87.5	Confident	40 Å²	40	56.1 Å²	56.1	24%	0.242	31%	0.313	C	S	.	.	H	α-helix	trans	-59.8	-54.7	-178.4	-179.6	0	0	0	0	112.5	F117 I121 L454 S455 V459 Y460 F461	F117-V457 HydrophobicContact CE2-CG1 4.32Å; F117-V457 HydrophobicContact CE2-CG2 4.27Å; F117-V457 HydrophobicContact CZ-CG1 4.34Å; F117-V457 HydrophobicContact CZ-CG2 3.96Å; I121-V457 HydrophobicContact CD1-CG2 3.93Å; L454-V457 HydrophobicContact CD2-CG2 4.32Å; L454-V457 VanDerWaalsContact O-CB 3.3Å; L454-V457 WeakPolarHBondContact O-CB 3.3Å; L454-V457 WeakPolarHBondContact O-CG2 3.37Å; L454-V457 PolarHBondContact O-N 2.93Å; S455-V457 VanDerWaalsContact C-N 3.29Å; S455-V457 PolarHBondContact O-N 3.08Å; V457-V459 VanDerWaalsContact C-N 3.26Å; V457-V459 PolarHBondContact O-N 2.85Å; V457-Y460 PolarHBondContact O-N 3.27Å; V457-F461 HydrophobicContact CG1-CD2 3.88Å; V457-F461 HydrophobicContact CG1-CE2 3.74Å; V457-F461 VanDerWaalsContact O-CD2 3.26Å; V457-F461 WeakPolarHBondContact O-CD2 3.34Å; V457-F461 PolarHBondContact O-N 3.36Å; V457-F461 VanDerWaalsContact O-N 3.15Å
458	P	91	Very high	86.5	Confident	73 Å²	73	58 Å²	58	47%	0.474	32%	0.319	S	S	.	.	H	α-helix	trans	-61.8	-35.6	176.8	23.8	-34.2	0	0	0	112.2	L454 S455 F461 L462	L454-P458 WeakPolarHBondContact O-CD 3.19Å; S455-P458 VanDerWaalsContact O-CD 3.27Å; S455-P458 WeakPolarHBondContact O-CD 3.21Å; S455-P458 VanDerWaalsContact O-CG 3.28Å; S455-P458 WeakPolarHBondContact O-CG 3.4Å; P458-F461 PolarHBondContact O-N 2.91Å; P458-L462 WeakPolarHBondContact O-CB 3.25Å; P458-L462 VanDerWaalsContact O-CG 3.24Å; P458-L462 WeakPolarHBondContact O-CG 3.45Å; P458-L462 PolarHBondContact O-N 2.97Å
459	V	89.6	Confident	85.6	Confident	57 Å²	57	60.4 Å²	60.4	35%	0.345	34%	0.341	S	S	.	.	H	α-helix	trans	-66.2	-41.1	178.4	-178.5	0	0	0	0	111.4	F120 W124 S455 G456 V457 G463	F120-V459 HydrophobicContact CZ-CB 4.19Å; F120-V459 HydrophobicContact CZ-CG1 3.93Å; W124-V459 HydrophobicContact CH2-CB 4.35Å; W124-V459 HydrophobicContact CH2-CG1 4.02Å; W124-V459 HydrophobicContact CH2-CG2 3.93Å; W124-V459 HydrophobicContact CZ2-CG2 3.97Å; W124-V459 HydrophobicContact CZ3-CG1 3.91Å; S455-V459 WeakPolarHBondContact O-CG2 3.29Å; G456-V459 PolarHBondContact O-N 2.99Å; V457-V459 VanDerWaalsContact C-N 3.26Å; V457-V459 PolarHBondContact O-N 2.85Å; V459-G463 WeakPolarHBondContact O-CA 3.35Å; V459-G463 PolarHBondContact O-N 3.44Å
460	Y	88.7	Confident	85.1	Confident	27 Å²	27	67.5 Å²	67.5	11%	0.106	37%	0.371	C	S	.	.	H	α-helix	trans	-61.6	-48	176	180	-99.7	0	0	0	111.6	F117 F120 G456 V457 L462 V464 Y465	F117-Y460 HydrophobicContact CB-CE1 3.96Å; F117-Y460 AromaticContact CD2-CD1 3.42Å; F117-Y460 HydrophobicContact CD2-CD1 3.42Å; F117-Y460 VanDerWaalsContact CD2-CD1 3.42Å; F117-Y460 HydrophobicContact CD2-CD2 4.44Å; F117-Y460 AromaticContact CD2-CE1 3.65Å; F117-Y460 HydrophobicContact CD2-CE1 3.65Å; F117-Y460 AromaticContact CD2-CG 3.83Å; F117-Y460 HydrophobicContact CD2-CG 3.83Å; F117-Y460 HydrophobicContact CE2-CD1 4.06Å; F117-Y460 HydrophobicContact CE2-CG 4.38Å; F117-Y460 HydrophobicContact CG-CD1 4.45Å; F117-Y460 HydrophobicContact CG-CE1 4.26Å; F117-Y460 PolarHBondContact N-OH 3.15Å; F120-Y460 HydrophobicContact CB-CD2 3.47Å; F120-Y460 VanDerWaalsContact CB-CD2 3.47Å; F120-Y460 HydrophobicContact CB-CE2 3.79Å; F120-Y460 HydrophobicContact CB-CG 4.49Å; F120-Y460 AromaticContact CD1-CD2 3.76Å; F120-Y460 HydrophobicContact CD1-CD2 3.76Å; F120-Y460 HydrophobicContact CD1-CG 4.12Å; F120-Y460 AromaticContact CD2-CD2 3.84Å; F120-Y460 HydrophobicContact CD2-CD2 3.84Å; F120-Y460 AromaticContact CG-CD2 3.4Å; F120-Y460 HydrophobicContact CG-CD2 3.4Å; F120-Y460 HydrophobicContact CG-CE2 4.2Å; F120-Y460 HydrophobicContact CG-CG 4.22Å; G456-Y460 WeakPolarHBondContact O-CB 3.37Å; G456-Y460 PolarHBondContact O-N 3.23Å; V457-Y460 PolarHBondContact O-N 3.27Å; Y460-L462 PolarHBondContact O-N 3.3Å; Y460-V464 HydrophobicContact CD2-CB 3.77Å; Y460-V464 HydrophobicContact CD2-CG1 4.1Å; Y460-V464 HydrophobicContact CD2-CG2 4.05Å; Y460-V464 HydrophobicContact CE2-CB 3.85Å; Y460-V464 HydrophobicContact CE2-CG1 3.65Å; Y460-V464 HydrophobicContact CE2-CG2 4.43Å; Y460-V464 HydrophobicContact CG-CB 4.44Å; Y460-V464 WeakPolarHBondContact O-CA 3.3Å; Y460-V464 WeakPolarHBondContact O-CB 3.11Å; Y460-V464 PolarHBondContact O-N 2.86Å; Y460-Y465 HydrophobicContact CE1-CD2 4.47Å; Y460-Y465 PolarHBondContact O-N 3.43Å
461	F	86.9	Confident	84.6	Confident	93 Å²	93	67 Å²	67	41%	0.408	37%	0.366	S	S	.	.	I	π-helix	trans	-64.6	-44	-178.2	-79.5	-68.3	0	0	0	111.6	F117 V457 P458 Y465 L466	F117-F461 HydrophobicContact CE2-CE2 4.38Å; V457-F461 HydrophobicContact CG1-CD2 3.88Å; V457-F461 HydrophobicContact CG1-CE2 3.74Å; V457-F461 VanDerWaalsContact O-CD2 3.26Å; V457-F461 WeakPolarHBondContact O-CD2 3.34Å; V457-F461 PolarHBondContact O-N 3.36Å; V457-F461 VanDerWaalsContact O-N 3.15Å; P458-F461 PolarHBondContact O-N 2.91Å; F461-Y465 AromaticContact CD1-CD1 3.83Å; F461-Y465 HydrophobicContact CD1-CD1 3.83Å; F461-Y465 AromaticContact CD1-CG 3.96Å; F461-Y465 HydrophobicContact CD1-CG 3.96Å; F461-Y465 HydrophobicContact CE1-CD1 4.25Å; F461-Y465 HydrophobicContact CE1-CG 4.28Å; F461-L466 WeakPolarHBondContact O-CB 3.4Å; F461-L466 VanDerWaalsContact O-CD1 3.28Å; F461-L466 WeakPolarHBondContact O-CD1 3.41Å; F461-L466 WeakPolarHBondContact O-CG 3.47Å; F461-L466 PolarHBondContact O-N 3.47Å; F461-L466 VanDerWaalsContact O-N 3.09Å
462	L	84.1	Confident	84.2	Confident	69 Å²	69	66.6 Å²	66.6	36%	0.361	36%	0.358	S	S	.	.	I	π-helix	trans	-73.8	-36.8	-179.4	-67.3	171.7	0	0	0	113.8	P458 Y460 L466 P472 I475	P458-L462 WeakPolarHBondContact O-CB 3.25Å; P458-L462 VanDerWaalsContact O-CG 3.24Å; P458-L462 WeakPolarHBondContact O-CG 3.45Å; P458-L462 PolarHBondContact O-N 2.97Å; Y460-L462 PolarHBondContact O-N 3.3Å; L462-L466 HydrophobicContact CD2-CD1 4.19Å; L462-P472 HydrophobicContact CD2-CG 4.37Å; L462-I475 HydrophobicContact CB-CD1 4.14Å; L462-I475 HydrophobicContact CD1-CD1 4.16Å; L462-I475 HydrophobicContact CD2-CD1 4.44Å; L462-I475 HydrophobicContact CG-CD1 4.49Å
463	G	79.7	Confident	83.7	Confident	24 Å²	24	69.5 Å²	69.5	25%	0.247	38%	0.379	C	S	.	.	I	π-helix	trans	-98.6	-32.7	-170.2	0	0	0	0	0	114.8	V459 R471	V459-G463 WeakPolarHBondContact O-CA 3.35Å; V459-G463 PolarHBondContact O-N 3.44Å; G463-R471 PolarHBondContact O-NE 3.24Å; G463-R471 PolarHBondContact O-NH2 3.42Å
464	V	80.7	Confident	83.4	Confident	35 Å²	35	75.3 Å²	75.3	21%	0.212	41%	0.407	C	S	.	.	I	π-helix	trans	-115.8	-52.1	-171.2	-177	0	0	0	0	111.4	F120 Y460	F120-V464 HydrophobicContact CD2-CG2 4.02Å; F120-V464 HydrophobicContact CE2-CG2 4.09Å; Y460-V464 HydrophobicContact CD2-CB 3.77Å; Y460-V464 HydrophobicContact CD2-CG1 4.1Å; Y460-V464 HydrophobicContact CD2-CG2 4.05Å; Y460-V464 HydrophobicContact CE2-CB 3.85Å; Y460-V464 HydrophobicContact CE2-CG1 3.65Å; Y460-V464 HydrophobicContact CE2-CG2 4.43Å; Y460-V464 HydrophobicContact CG-CB 4.44Å; Y460-V464 WeakPolarHBondContact O-CA 3.3Å; Y460-V464 WeakPolarHBondContact O-CB 3.11Å; Y460-V464 PolarHBondContact O-N 2.86Å
465	Y	82.6	Confident	82.9	Confident	159 Å²	159	72.4 Å²	72.4	62%	0.624	39%	0.391	S	S	*	.	I	π-helix	trans	-70.9	-40.4	-175.1	-175.6	-99.6	0	0	0	113	Y460 F461 P467	Y460-Y465 HydrophobicContact CE1-CD2 4.47Å; Y460-Y465 PolarHBondContact O-N 3.43Å; F461-Y465 AromaticContact CD1-CD1 3.83Å; F461-Y465 HydrophobicContact CD1-CD1 3.83Å; F461-Y465 AromaticContact CD1-CG 3.96Å; F461-Y465 HydrophobicContact CD1-CG 3.96Å; F461-Y465 HydrophobicContact CE1-CD1 4.25Å; F461-Y465 HydrophobicContact CE1-CG 4.28Å; Y465-P467 WeakPolarHBondContact O-CD 3.05Å
466	L	77.9	Confident	82.2	Confident	47 Å²	47	72.8 Å²	72.8	25%	0.246	39%	0.389	C	S	.	.	S	Bend	trans	-71.8	122.5	177.2	-88.8	153.2	0	0	0	110.3	F461 L462 K470 R471	F461-L466 WeakPolarHBondContact O-CB 3.4Å; F461-L466 VanDerWaalsContact O-CD1 3.28Å; F461-L466 WeakPolarHBondContact O-CD1 3.41Å; F461-L466 WeakPolarHBondContact O-CG 3.47Å; F461-L466 PolarHBondContact O-N 3.47Å; F461-L466 VanDerWaalsContact O-N 3.09Å; L462-L466 HydrophobicContact CD2-CD1 4.19Å; L466-K470 HydrophobicContact CD2-CB 3.58Å; L466-K470 HydrophobicContact CD2-CD 4.45Å; L466-R471 HydrophobicContact CB-CG 4.17Å; L466-R471 PolarHBondContact O-NE 2.98Å
467	P	71.6	Confident	82	Confident	69 Å²	69	80.7 Å²	80.7	45%	0.448	42%	0.423	S	S	.	.			trans	-59.9	148.6	173.2	23.7	-31.2	0	0	0	109.6	Y465 S469 K470 R471	Y465-P467 WeakPolarHBondContact O-CD 3.05Å; P467-S469 PolarHBondContact O-N 3.02Å; P467-K470 HydrophobicContact CG-CB 4.31Å; P467-K470 HydrophobicContact CG-CD 4.11Å; P467-K470 HydrophobicContact CG-CG 4.18Å; P467-K470 PolarHBondContact O-N 3.32Å; P467-R471 PolarHBondContact O-N 2.86Å
468	E	69.8	Low	81.6	Confident	135 Å²	135	84.5 Å²	84.5	63%	0.631	44%	0.442	S	S	*	.	G	3₁₀ helix	trans	-50.7	-35	-173.1	-64.7	-159.8	143.8	0	0	113.5	K470 R471 I476	E468-K470 VanDerWaalsContact C-N 3.26Å; E468-K470 PolarHBondContact O-N 2.9Å; E468-R471 PolarHBondContact O-N 3.33Å; E468-R471 IonicContact OE1-NH1 3.24Å; E468-I476 WeakPolarHBondContact O-CD1 3.43Å
469	S	69.9	Low	81.3	Confident	111 Å²	111	83.3 Å²	83.3	78%	0.776	43%	0.431	S	S	*	.	G	3₁₀ helix	trans	-64.9	-22.4	178.5	58	0	0	0	0	114.9	P467	P467-S469 PolarHBondContact O-N 3.02Å
470	K	76.6	Confident	81	Confident	152 Å²	152	88.2 Å²	88.2	66%	0.661	44%	0.443	S	S	*	.	G	3₁₀ helix	trans	-105.8	-1.1	-179.7	-65.6	-173	179.5	-179.2	0	113.2	L466 P467 E468	L466-K470 HydrophobicContact CD2-CB 3.58Å; L466-K470 HydrophobicContact CD2-CD 4.45Å; P467-K470 HydrophobicContact CG-CB 4.31Å; P467-K470 HydrophobicContact CG-CD 4.11Å; P467-K470 HydrophobicContact CG-CG 4.18Å; P467-K470 PolarHBondContact O-N 3.32Å; E468-K470 VanDerWaalsContact C-N 3.26Å; E468-K470 PolarHBondContact O-N 2.9Å
471	R	81.4	Confident	80.9	Confident	47 Å²	47	90.6 Å²	90.6	18%	0.177	46%	0.464	C	S	.	.	S	Bend	trans	-70.9	142.9	178.1	-64.3	-176.5	-171	162	1.1	110	G463 L466 P467 E468 I476	G463-R471 PolarHBondContact O-NE 3.24Å; G463-R471 PolarHBondContact O-NH2 3.42Å; L466-R471 HydrophobicContact CB-CG 4.17Å; L466-R471 PolarHBondContact O-NE 2.98Å; P467-R471 PolarHBondContact O-N 2.86Å; E468-R471 PolarHBondContact O-N 3.33Å; E468-R471 IonicContact OE1-NH1 3.24Å; R471-I476 HydrophobicContact CB-CD1 4.01Å; R471-I476 HydrophobicContact CB-CG1 3.83Å
472	P	82.6	Confident	80.8	Confident	48 Å²	48	90 Å²	90	31%	0.312	46%	0.464	S	S	.	.			trans	-53.1	133.8	174.1	-26.2	33.2	0	0	0	111.2	L462 I474 I475 I476	L462-P472 HydrophobicContact CD2-CG 4.37Å; P472-I474 PolarHBondContact O-N 3.3Å; P472-I474 VanDerWaalsContact O-N 3.09Å; P472-I475 HydrophobicContact CB-CD1 4.25Å; P472-I475 HydrophobicContact CB-CG1 4.23Å; P472-I475 HydrophobicContact CG-CD1 3.94Å; P472-I475 HydrophobicContact CG-CG1 4.46Å; P472-I475 PolarHBondContact O-N 3.49Å; P472-I476 PolarHBondContact O-N 2.7Å
473	P	81.5	Confident	80.9	Confident	103 Å²	103	88 Å²	88	67%	0.669	46%	0.456	S	S	*	.	H	α-helix	trans	-60.7	-26.7	-175.4	21.2	-31.8	0	0	0	112.9	K477	P473-K477 VanDerWaalsContact O-CB 3.31Å; P473-K477 WeakPolarHBondContact O-CB 3.49Å; P473-K477 PolarHBondContact O-N 3.32Å
474	I	84.8	Confident	81.2	Confident	138 Å²	138	91.8 Å²	91.8	71%	0.708	47%	0.465	S	S	*	.	H	α-helix	trans	-62.4	-45.2	173.6	-61.9	168.1	0	0	0	110.9	P472 K477 L478	P472-I474 PolarHBondContact O-N 3.3Å; P472-I474 VanDerWaalsContact O-N 3.09Å; I474-K477 PolarHBondContact O-N 3.38Å; I474-L478 WeakPolarHBondContact O-CB 3.21Å; I474-L478 PolarHBondContact O-N 2.92Å
475	I	82.1	Confident	81.5	Confident	45 Å²	45	96.4 Å²	96.4	23%	0.231	48%	0.483	C	S	.	.	H	α-helix	trans	-67.8	-42.9	-179.5	-64.2	-179.8	0	0	0	110	L462 P472 K477 L478 L479	L462-I475 HydrophobicContact CB-CD1 4.14Å; L462-I475 HydrophobicContact CD1-CD1 4.16Å; L462-I475 HydrophobicContact CD2-CD1 4.44Å; L462-I475 HydrophobicContact CG-CD1 4.49Å; P472-I475 HydrophobicContact CB-CD1 4.25Å; P472-I475 HydrophobicContact CB-CG1 4.23Å; P472-I475 HydrophobicContact CG-CD1 3.94Å; P472-I475 HydrophobicContact CG-CG1 4.46Å; P472-I475 PolarHBondContact O-N 3.49Å; I475-K477 VanDerWaalsContact C-N 3.33Å; I475-K477 PolarHBondContact O-N 3.41Å; I475-L478 PolarHBondContact O-N 3.23Å; I475-L479 HydrophobicContact CG2-CD1 3.83Å; I475-L479 HydrophobicContact CG2-CG 4.2Å; I475-L479 WeakPolarHBondContact O-CB 3.23Å; I475-L479 WeakPolarHBondContact O-CG 3.34Å; I475-L479 PolarHBondContact O-N 2.91Å
476	I	81.5	Confident	81.6	Confident	57 Å²	57	89.5 Å²	89.5	29%	0.292	46%	0.457	S	S	.	.	H	α-helix	trans	-60.3	-45.5	175.9	-60.2	172.6	0	0	0	110.4	E468 R471 P472 R480	E468-I476 WeakPolarHBondContact O-CD1 3.43Å; R471-I476 HydrophobicContact CB-CD1 4.01Å; R471-I476 HydrophobicContact CB-CG1 3.83Å; P472-I476 PolarHBondContact O-N 2.7Å; I476-R480 WeakPolarHBondContact O-CB 3.46Å; I476-R480 PolarHBondContact O-N 3.21Å
477	K	85.6	Confident	82	Confident	166 Å²	166	90.1 Å²	90.1	72%	0.722	46%	0.459	S	S	*	.	H	α-helix	trans	-63.5	-41.5	178	-170.9	176.4	-179.5	-179.7	0	111.6	P473 I474 I475 S481	P473-K477 VanDerWaalsContact O-CB 3.31Å; P473-K477 WeakPolarHBondContact O-CB 3.49Å; P473-K477 PolarHBondContact O-N 3.32Å; I474-K477 PolarHBondContact O-N 3.38Å; I475-K477 VanDerWaalsContact C-N 3.33Å; I475-K477 PolarHBondContact O-N 3.41Å; K477-S481 WeakPolarHBondContact O-CB 3.26Å; K477-S481 PolarHBondContact O-N 2.96Å
478	L	85.6	Confident	82.8	Confident	120 Å²	120	95.2 Å²	95.2	63%	0.628	47%	0.47	S	S	*	.	H	α-helix	trans	-63.9	-52.3	176.9	-177.2	71.8	0	0	0	111.4	I474 I475 R480 S481 L482	I474-L478 WeakPolarHBondContact O-CB 3.21Å; I474-L478 PolarHBondContact O-N 2.92Å; I475-L478 PolarHBondContact O-N 3.23Å; L478-R480 VanDerWaalsContact C-N 3.34Å; L478-R480 PolarHBondContact O-N 3.39Å; L478-S481 PolarHBondContact O-N 3.47Å; L478-L482 WeakPolarHBondContact O-CB 3.28Å; L478-L482 PolarHBondContact O-N 3.41Å
479	L	83.5	Confident	83.6	Confident	47 Å²	47	92.2 Å²	92.2	25%	0.246	46%	0.461	C	S	.	.	H	α-helix	trans	-59.6	-45.5	179.1	-71.8	174	0	0	0	110.8	P348 I475 S481 L482 T483	P348-L479 HydrophobicContact CB-CD2 4.04Å; P348-L479 HydrophobicContact CG-CD2 4.04Å; I475-L479 HydrophobicContact CG2-CD1 3.83Å; I475-L479 HydrophobicContact CG2-CG 4.2Å; I475-L479 WeakPolarHBondContact O-CB 3.23Å; I475-L479 WeakPolarHBondContact O-CG 3.34Å; I475-L479 PolarHBondContact O-N 2.91Å; L479-S481 PolarHBondContact O-N 2.99Å; L479-L482 PolarHBondContact O-N 2.99Å; L479-T483 WeakPolarHBondContact O-CB 3.35Å; L479-T483 PolarHBondContact O-N 2.97Å; L479-T483 PolarHBondContact O-OG1 3.5Å
480	R	84.2	Confident	84.4	Confident	161 Å²	161	88 Å²	88	61%	0.608	43%	0.431	S	S	*	.	H	α-helix	trans	-62.6	-43.4	176.4	-173.3	179.6	-69.5	175.1	-0.6	111.7	I476 L478 L482 T483 F484	I476-R480 WeakPolarHBondContact O-CB 3.46Å; I476-R480 PolarHBondContact O-N 3.21Å; L478-R480 VanDerWaalsContact C-N 3.34Å; L478-R480 PolarHBondContact O-N 3.39Å; R480-L482 VanDerWaalsContact C-N 3.35Å; R480-T483 PolarHBondContact O-N 3.36Å; R480-F484 HydrophobicContact CG-CD2 3.69Å; R480-F484 HydrophobicContact CG-CE2 3.55Å; R480-F484 WeakPolarHBondContact O-CD2 3.34Å; R480-F484 PolarHBondContact O-N 3.13Å
481	S	86.3	Confident	84.9	Confident	76 Å²	76	87.4 Å²	87.4	53%	0.531	43%	0.429	S	S	.	.	H	α-helix	trans	-63.7	-40.8	176.8	-170.2	0	0	0	0	111.9	K477 L478 L479 F485	K477-S481 WeakPolarHBondContact O-CB 3.26Å; K477-S481 PolarHBondContact O-N 2.96Å; L478-S481 PolarHBondContact O-N 3.47Å; L479-S481 PolarHBondContact O-N 2.99Å; S481-F485 WeakPolarHBondContact O-CB 3.47Å; S481-F485 PolarHBondContact O-N 3.47Å
482	L	85.5	Confident	85.1	Confident	80 Å²	80	85.3 Å²	85.3	42%	0.419	42%	0.422	S	S	.	.	H	α-helix	trans	-62.7	-51.2	175.8	-173.2	79.7	0	0	0	110	A350 L478 L479 R480 F484 F485 T486	A350-L482 HydrophobicContact CB-CD2 4.06Å; A350-L482 HydrophobicContact CB-CG 4.37Å; L478-L482 WeakPolarHBondContact O-CB 3.28Å; L478-L482 PolarHBondContact O-N 3.41Å; L479-L482 PolarHBondContact O-N 2.99Å; R480-L482 VanDerWaalsContact C-N 3.35Å; L482-F484 PolarHBondContact O-N 3.27Å; L482-F485 PolarHBondContact O-N 3.42Å; L482-T486 WeakPolarHBondContact O-CB 3.45Å; L482-T486 PolarHBondContact O-N 3.14Å; L482-T486 PolarHBondContact O-OG1 3.41Å
483	T	85.4	Confident	85.1	Confident	29 Å²	29	86.4 Å²	86.4	18%	0.178	43%	0.427	C	S	.	.	H	α-helix	trans	-54	-50.9	176.4	-64	0	0	0	0	111.2	M353 L479 R480 T486 Q487	M353-T483 HydrophobicContact CE-CG2 3.25Å; L479-T483 WeakPolarHBondContact O-CB 3.35Å; L479-T483 PolarHBondContact O-N 2.97Å; L479-T483 PolarHBondContact O-OG1 3.5Å; R480-T483 PolarHBondContact O-N 3.36Å; T483-T486 PolarHBondContact O-N 2.95Å; T483-Q487 WeakPolarHBondContact O-CB 3.32Å; T483-Q487 VanDerWaalsContact O-CG 3.24Å; T483-Q487 WeakPolarHBondContact O-CG 3.39Å; T483-Q487 PolarHBondContact O-N 2.96Å
484	F	85.9	Confident	85	Confident	102 Å²	102	84.8 Å²	84.8	45%	0.447	41%	0.413	S	S	.	.	H	α-helix	trans	-62.8	-47.1	177.4	-85	-64.2	0	0	0	112.2	R480 L482 T486 Q487 Y488	R480-F484 HydrophobicContact CG-CD2 3.69Å; R480-F484 HydrophobicContact CG-CE2 3.55Å; R480-F484 WeakPolarHBondContact O-CD2 3.34Å; R480-F484 PolarHBondContact O-N 3.13Å; L482-F484 PolarHBondContact O-N 3.27Å; F484-T486 VanDerWaalsContact C-N 3.32Å; F484-T486 PolarHBondContact O-N 3.38Å; F484-Q487 PolarHBondContact O-N 3.38Å; F484-Y488 HydrophobicContact CD1-CE2 4.08Å; F484-Y488 VanDerWaalsContact O-CD2 3.26Å; F484-Y488 WeakPolarHBondContact O-CD2 3.42Å; F484-Y488 PolarHBondContact O-N 2.97Å
485	F	87.6	Confident	84.2	Confident	133 Å²	133	80 Å²	80	58%	0.583	39%	0.39	S	S	*	.	H	α-helix	trans	-55.5	-50.9	178.1	179.1	-99	0	0	0	110.5	S481 L482 Q487 Y488 T489	S481-F485 WeakPolarHBondContact O-CB 3.47Å; S481-F485 PolarHBondContact O-N 3.47Å; L482-F485 PolarHBondContact O-N 3.42Å; F485-Q487 PolarHBondContact O-N 2.94Å; F485-Y488 PolarHBondContact O-N 3.3Å; F485-T489 HydrophobicContact CD1-CG2 4.27Å; F485-T489 HydrophobicContact CD2-CG2 3.92Å; F485-T489 HydrophobicContact CE1-CG2 3.98Å; F485-T489 HydrophobicContact CE2-CG2 3.61Å; F485-T489 HydrophobicContact CG-CG2 4.26Å; F485-T489 HydrophobicContact CZ-CG2 3.64Å; F485-T489 WeakPolarHBondContact O-CB 3.33Å; F485-T489 WeakPolarHBondContact O-CG2 3.34Å; F485-T489 PolarHBondContact O-N 2.96Å; F485-T489 PolarHBondContact O-OG1 2.79Å
486	T	85.1	Confident	83.1	Confident	14 Å²	14	86.8 Å²	86.8	9%	0.086	42%	0.421	C	S	.	.	H	α-helix	trans	-59.5	-42.8	177.8	-58.9	0	0	0	0	112.5	M353 P363 L482 T483 F484 C490	M353-T486 HydrophobicContact SD-CG2 3.97Å; P363-T486 HydrophobicContact CB-CG2 3.68Å; P363-T486 HydrophobicContact CG-CG2 3.23Å; L482-T486 WeakPolarHBondContact O-CB 3.45Å; L482-T486 PolarHBondContact O-N 3.14Å; L482-T486 PolarHBondContact O-OG1 3.41Å; T483-T486 PolarHBondContact O-N 2.95Å; F484-T486 VanDerWaalsContact C-N 3.32Å; F484-T486 PolarHBondContact O-N 3.38Å; T486-C490 WeakPolarHBondContact O-CB 3.34Å; T486-C490 PolarHBondContact O-N 2.82Å
487	Q	86.4	Confident	81.5	Confident	60 Å²	60	88.4 Å²	88.4	28%	0.28	43%	0.433	S	S	.	.	H	α-helix	trans	-60.8	-46.5	177.1	-75.4	174.7	-18.3	0	0	111.8	M353 T483 F484 F485 F491 C492	M353-Q487 HydrophobicContact CE-CG 3.68Å; M353-Q487 HydrophobicContact SD-CG 3.61Å; T483-Q487 WeakPolarHBondContact O-CB 3.32Å; T483-Q487 VanDerWaalsContact O-CG 3.24Å; T483-Q487 WeakPolarHBondContact O-CG 3.39Å; T483-Q487 PolarHBondContact O-N 2.96Å; F484-Q487 PolarHBondContact O-N 3.38Å; F485-Q487 PolarHBondContact O-N 2.94Å; Q487-F491 VanDerWaalsContact O-CA 3.24Å; Q487-F491 WeakPolarHBondContact O-CA 3.42Å; Q487-F491 PolarHBondContact O-N 3.2Å; Q487-C492 WeakPolarHBondContact CG-O 3.43Å; Q487-C492 PolarHBondContact O-N 3.48Å
488	Y	87	Confident	79.2	Confident	176 Å²	176	85.9 Å²	85.9	69%	0.69	43%	0.428	S	S	*	.	H	α-helix	trans	-73.3	-43	-178.7	-82.3	-75.7	0	0	0	112.9	F484 F485	F484-Y488 HydrophobicContact CD1-CE2 4.08Å; F484-Y488 VanDerWaalsContact O-CD2 3.26Å; F484-Y488 WeakPolarHBondContact O-CD2 3.42Å; F484-Y488 PolarHBondContact O-N 2.97Å; F485-Y488 PolarHBondContact O-N 3.3Å
489	T	87.7	Confident	76.5	Confident	72 Å²	72	89.9 Å²	89.9	44%	0.442	44%	0.44	S	S	.	.	H	α-helix	trans	-76.5	-36.2	-176.7	57.6	0	0	0	0	112.6	F485	F485-T489 HydrophobicContact CD1-CG2 4.27Å; F485-T489 HydrophobicContact CD2-CG2 3.92Å; F485-T489 HydrophobicContact CE1-CG2 3.98Å; F485-T489 HydrophobicContact CE2-CG2 3.61Å; F485-T489 HydrophobicContact CG-CG2 4.26Å; F485-T489 HydrophobicContact CZ-CG2 3.64Å; F485-T489 WeakPolarHBondContact O-CB 3.33Å; F485-T489 WeakPolarHBondContact O-CG2 3.34Å; F485-T489 PolarHBondContact O-N 2.96Å; F485-T489 PolarHBondContact O-OG1 2.79Å
490	C	85.6	Confident	74	Confident	22 Å²	22	91.3 Å²	91.3	15%	0.149	45%	0.454	C	S	.	.	H	α-helix	trans	-102.7	-0.6	-175	-56.8	0	0	0	0	113.2	H355 I362 T486 C492	H355-C490 PolarHBondContact CD2-O 3.17Å; I362-C490 HydrophobicContact CG2-CB 4.34Å; T486-C490 WeakPolarHBondContact O-CB 3.34Å; T486-C490 PolarHBondContact O-N 2.82Å; C490-C492 HydrophobicContact CB-CB 4.4Å; C490-C492 VanDerWaalsContact CB-SG 3.53Å; C490-C492 PolarHBondContact O-N 3.13Å; C490-C492 PolarHBondContact O-SG 3.15Å
491	F	87.6	Confident	71.3	Confident	139 Å²	139	96.5 Å²	96.5	61%	0.61	49%	0.485	S	S	*	.	T	Hydrogen-bonded Turn	trans	48	45.7	-175.2	-65.7	-86.4	0	0	0	112.4	I356 Q487	I356-F491 WeakPolarHBondContact CG1-O 3.43Å; I356-F491 PolarHBondContact N-O 3.3Å; Q487-F491 VanDerWaalsContact O-CA 3.24Å; Q487-F491 WeakPolarHBondContact O-CA 3.42Å; Q487-F491 PolarHBondContact O-N 3.2Å
492	C	85.5	Confident	70.6	Confident	4 Å²	4	97.5 Å²	97.5	3%	0.027	48%	0.483	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.2	151.2	-176.4	-65.5	0	0	0	0	111.4	M353 I354 Q487 C490	M353-C492 HydrophobicContact CB-CB 3.67Å; M353-C492 HydrophobicContact SD-CB 4.42Å; I354-C492 CarbonylContact O-C 3.38Å; I354-C492 VanDerWaalsContact O-CA 3.25Å; I354-C492 WeakPolarHBondContact O-CA 3.49Å; Q487-C492 WeakPolarHBondContact CG-O 3.43Å; Q487-C492 PolarHBondContact O-N 3.48Å; C490-C492 HydrophobicContact CB-CB 4.4Å; C490-C492 VanDerWaalsContact CB-SG 3.53Å; C490-C492 PolarHBondContact O-N 3.13Å; C490-C492 PolarHBondContact O-SG 3.15Å
493	V	83.9	Confident	69.8	Low	71 Å²	71	98.4 Å²	98.4	43%	0.43	49%	0.486	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.8	152	176.6	-69.7	0	0	0	0	109.7	M353 I354 I356	M353-V493 WeakPolarHBondContact CA-O 3.48Å; I354-V493 PolarHBondContact N-O 3.4Å; I354-V493 PolarHBondContact O-N 3.22Å; I356-V493 HydrophobicContact CD1-CG1 3.92Å; I356-V493 HydrophobicContact CG1-CB 4.46Å; I356-V493 HydrophobicContact CG1-CG1 3.74Å; I356-V493 HydrophobicContact CG1-CG2 3.97Å
494	L	79.3	Confident	68.9	Low	68 Å²	68	102.3 Å²	102.3	36%	0.356	50%	0.503	S	S	.	.	P	Polyproline II helix	trans	-64.7	140	168.4	-107.6	94.5	0	0	0	109.2	D349 M353	D349-L494 HydrophobicContact CB-CD1 3.84Å; D349-L494 HydrophobicContact CB-CD2 4.08Å; D349-L494 HydrophobicContact CB-CG 4.33Å; M353-L494 HydrophobicContact CE-CD1 3.68Å; M353-L494 HydrophobicContact CG-CD1 4.02Å
495	T	67.6	Low	68	Low	39 Å²	39	102.3 Å²	102.3	24%	0.239	51%	0.507	C	S	.	.	P	Polyproline II helix	trans	-65.8	137.4	164.4	46	0	0	0	0	109.5	F339 I354 T497	F339-T495 HydrophobicContact CE2-CG2 3.74Å; F339-T495 HydrophobicContact CZ-CG2 3.79Å; I354-T495 HydrophobicContact CB-CG2 4.39Å; I354-T495 HydrophobicContact CD1-CG2 3.27Å; I354-T495 HydrophobicContact CG1-CG2 3.74Å; T495-T497 PolarHBondContact O-N 3.15Å
496	E	57.6	Low	66.7	Low	186 Å²	186	100.4 Å²	100.4	87%	0.869	50%	0.502	S	S	*	.	P	Polyproline II helix	trans	-53.4	117.5	167.5	-70.7	-173.7	160.3	0	0	108	D498	E496-D498 PolarHBondContact O-N 2.98Å
497	T	49	Very low	65.5	Low	91 Å²	91	106.1 Å²	106.1	56%	0.558	53%	0.53	S	S	*	.	P	Polyproline II helix	trans	-57.7	122.1	167.7	40.3	0	0	0	0	106.8	T495 K499	T495-T497 PolarHBondContact O-N 3.15Å; T497-K499 PolarHBondContact O-N 3.13Å
498	D	36.7	Very low	64	Low	114 Å²	114	109.4 Å²	109.4	61%	0.61	55%	0.547	S	S	*	.			trans	-47.3	106.8	163.4	-79.9	-47.9	0	0	0	107	R343 E496 S500	R343-D498 IonicContact CZ-OD2 2.67Å; R343-D498 IonicContact NH2-OD2 2.7Å; R343-D498 PolarHBondContact NH2-OD2 3.29Å; E496-D498 PolarHBondContact O-N 2.98Å; D498-S500 PolarHBondContact O-N 3.25Å
499	K	29	Very low	62.2	Low	204 Å²	204	104.3 Å²	104.3	89%	0.887	54%	0.536	S	S	*	.			trans	-70.8	78.5	175.3	-77.6	-176.4	177.7	176.2	0	107.5	T497	T497-K499 PolarHBondContact O-N 3.13Å
500	S	31	Very low	60.1	Low	77 Å²	77	107 Å²	107	54%	0.538	54%	0.544	S	S	.	.			trans	-158.2	91	168.9	61.8	0	0	0	0	111	D498	D498-S500 PolarHBondContact O-N 3.25Å
501	Q	28.6	Very low	57.8	Low	269 Å²	269	114.7 Å²	114.7	100%	1.257	58%	0.58	S	S	*	*				-152.4	0	124.8	-105.1	174.6	30.4	0	0	109.1

Retrieved 501 of 501 residues in 962.2 ms (Link to these results)

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