A0A087XQI1_POEFO Loading...

Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the third and last glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(2)Man(9)GlcNAc(2)-PP-Dol to produce Glc(3)Man(9)GlcNAc(2)-PP-Dol.

AlphaFold DB , UniProt , Accession A0A087XQI1, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 477 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	57.4	Low	75.7	Confident	143 Å²	143	97.1 Å²	97.1	70%	0.704	48%	0.477	S	S	*	.				0	-48.7	0	-164	167.8	65.3	0	0	110.9	D3 M4 E5 K124	M1-D3 PolarHBondContact O-N 2.76Å; M1-M4 PolarHBondContact O-N 3.22Å; M1-E5 PolarHBondContact O-N 2.96Å; M1-K124 HydrophobicContact SD-CD 4.3Å; M1-K124 PolarHBondContact SD-NZ 3.13Å
2	Q	61.5	Low	76.7	Confident	138 Å²	138	90.9 Å²	90.9	65%	0.645	45%	0.446	S	S	*	.	H	α-helix	trans	-59	-38.4	176.4	-161.3	172	2.1	0	0	114.1	M4 E5 K6	Q2-M4 VanDerWaalsContact C-N 3.34Å; Q2-M4 PolarHBondContact O-N 2.89Å; Q2-E5 PolarHBondContact O-N 3.27Å; Q2-K6 WeakPolarHBondContact O-CG 3.37Å; Q2-K6 PolarHBondContact O-N 3.35Å; Q2-K6 VanDerWaalsContact O-N 3.14Å
3	D	69.1	Low	77.6	Confident	112 Å²	112	89 Å²	89	60%	0.599	45%	0.447	S	S	*	.	H	α-helix	trans	-68.6	-31.6	176.2	-61.4	-37.5	0	0	0	113.2	M1 K6 V7	M1-D3 PolarHBondContact O-N 2.76Å; D3-K6 PolarHBondContact O-N 2.94Å; D3-V7 VanDerWaalsContact O-CG2 3.26Å; D3-V7 WeakPolarHBondContact O-CG2 3.28Å; D3-V7 PolarHBondContact O-N 3.24Å
4	M	66.9	Low	78.7	Confident	78 Å²	78	86.5 Å²	86.5	38%	0.384	45%	0.447	S	S	.	.	H	α-helix	trans	-74.1	-35.3	177.1	-66.9	-162.1	-49.8	0	0	112.4	M1 Q2 K6 V7 E8 T125	M1-M4 PolarHBondContact O-N 3.22Å; Q2-M4 VanDerWaalsContact C-N 3.34Å; Q2-M4 PolarHBondContact O-N 2.89Å; M4-K6 VanDerWaalsContact C-N 3.32Å; M4-V7 PolarHBondContact O-N 2.96Å; M4-E8 WeakPolarHBondContact O-CB 3.29Å; M4-E8 PolarHBondContact O-N 2.88Å; M4-T125 HydrophobicContact CE-CG2 4.26Å; M4-T125 HydrophobicContact SD-CG2 3.82Å
5	E	73.8	Confident	79.5	Confident	103 Å²	103	84.2 Å²	84.2	48%	0.481	44%	0.435	S	S	.	.	H	α-helix	trans	-65.7	-37.9	173.7	-72.7	174.8	-178.7	0	0	110.9	M1 Q2 E8 S9	M1-E5 PolarHBondContact O-N 2.96Å; Q2-E5 PolarHBondContact O-N 3.27Å; E5-E8 PolarHBondContact O-N 3.32Å; E5-S9 WeakPolarHBondContact O-CB 3.29Å; E5-S9 PolarHBondContact O-N 3.46Å
6	K	79.1	Confident	80.3	Confident	105 Å²	105	80.9 Å²	80.9	46%	0.457	42%	0.421	S	S	.	.	H	α-helix	trans	-61.7	-47.6	170.7	-72.2	176.1	-178.3	174.1	0	111.7	Q2 D3 M4 E8 S9 Y10	Q2-K6 WeakPolarHBondContact O-CG 3.37Å; Q2-K6 PolarHBondContact O-N 3.35Å; Q2-K6 VanDerWaalsContact O-N 3.14Å; D3-K6 PolarHBondContact O-N 2.94Å; M4-K6 VanDerWaalsContact C-N 3.32Å; K6-E8 PolarHBondContact O-N 3.19Å; K6-S9 WeakPolarHBondContact O-CB 3.37Å; K6-S9 PolarHBondContact O-N 3.08Å; K6-Y10 HydrophobicContact CB-CE2 4.18Å; K6-Y10 WeakPolarHBondContact O-CD2 3.4Å; K6-Y10 PolarHBondContact O-N 3.43Å
7	V	82.8	Confident	81.1	Confident	72 Å²	72	80.1 Å²	80.1	44%	0.436	43%	0.425	S	S	.	.	H	α-helix	trans	-60.1	-45.2	177.8	169.7	0	0	0	0	111.7	D3 M4 S9 Y10 I11	D3-V7 VanDerWaalsContact O-CG2 3.26Å; D3-V7 WeakPolarHBondContact O-CG2 3.28Å; D3-V7 PolarHBondContact O-N 3.24Å; M4-V7 PolarHBondContact O-N 2.96Å; V7-S9 VanDerWaalsContact C-N 3.31Å; V7-S9 PolarHBondContact O-N 3.31Å; V7-Y10 PolarHBondContact O-N 3.29Å; V7-I11 HydrophobicContact CG1-CD1 3.69Å; V7-I11 HydrophobicContact CG1-CG1 4.33Å; V7-I11 VanDerWaalsContact O-CG1 3.32Å; V7-I11 WeakPolarHBondContact O-CG1 3.29Å; V7-I11 PolarHBondContact O-N 3.44Å
8	E	82.3	Confident	81.9	Confident	25 Å²	25	80.2 Å²	80.2	12%	0.117	43%	0.428	C	S	.	.	H	α-helix	trans	-59.3	-43.4	176	-177.6	164.5	-159.5	0	0	111.3	M4 E5 K6 Y10 I11 F12 Y113 M128 R131	M4-E8 WeakPolarHBondContact O-CB 3.29Å; M4-E8 PolarHBondContact O-N 2.88Å; E5-E8 PolarHBondContact O-N 3.32Å; K6-E8 PolarHBondContact O-N 3.19Å; E8-Y10 PolarHBondContact O-N 2.93Å; E8-I11 PolarHBondContact O-N 3.49Å; E8-F12 WeakPolarHBondContact O-CB 3.26Å; E8-F12 PolarHBondContact O-N 2.8Å; E8-Y113 VanDerWaalsContact CD-OH 3.24Å; E8-Y113 VanDerWaalsContact CG-OH 3.28Å; E8-Y113 WeakPolarHBondContact CG-OH 3.28Å; E8-Y113 PolarHBondContact OE1-OH 3.32Å; E8-M128 HydrophobicContact CB-CE 4.03Å; E8-M128 HydrophobicContact CB-CG 4.12Å; E8-M128 HydrophobicContact CB-SD 4.18Å; E8-M128 HydrophobicContact CG-CG 3.78Å; E8-M128 HydrophobicContact CG-SD 4.41Å; E8-R131 VanDerWaalsContact CD-NH2 3.25Å; E8-R131 IonicContact OE1-CZ 3.82Å; E8-R131 IonicContact OE1-NE 3.17Å; E8-R131 PolarHBondContact OE1-NE 3.33Å; E8-R131 IonicContact OE1-NH2 3.38Å; E8-R131 PolarHBondContact OE1-NH2 2.96Å; E8-R131 IonicContact OE2-NH2 3.16Å; E8-R131 PolarHBondContact OE2-NH2 3.48Å
9	S	83.8	Confident	82.5	Confident	72 Å²	72	76.6 Å²	76.6	50%	0.503	41%	0.409	S	S	.	.	H	α-helix	trans	-61.9	-41.9	176.4	-171.8	0	0	0	0	112.7	E5 K6 V7 S13	E5-S9 WeakPolarHBondContact O-CB 3.29Å; E5-S9 PolarHBondContact O-N 3.46Å; K6-S9 WeakPolarHBondContact O-CB 3.37Å; K6-S9 PolarHBondContact O-N 3.08Å; V7-S9 VanDerWaalsContact C-N 3.31Å; V7-S9 PolarHBondContact O-N 3.31Å; S9-S13 VanDerWaalsContact O-CB 3.31Å; S9-S13 WeakPolarHBondContact O-CB 3.14Å; S9-S13 PolarHBondContact O-N 3.41Å
10	Y	88	Confident	83.2	Confident	169 Å²	169	76.6 Å²	76.6	66%	0.663	41%	0.406	S	S	*	.	H	α-helix	trans	-66.2	-46	177.1	-70.3	-56.8	0	0	0	112	K6 V7 E8 F12 S13 A14	K6-Y10 HydrophobicContact CB-CE2 4.18Å; K6-Y10 WeakPolarHBondContact O-CD2 3.4Å; K6-Y10 PolarHBondContact O-N 3.43Å; V7-Y10 PolarHBondContact O-N 3.29Å; E8-Y10 PolarHBondContact O-N 2.93Å; Y10-F12 VanDerWaalsContact C-N 3.33Å; Y10-F12 PolarHBondContact O-N 2.82Å; Y10-S13 PolarHBondContact O-N 2.85Å; Y10-A14 WeakPolarHBondContact O-CB 3.47Å; Y10-A14 PolarHBondContact O-N 3.31Å
11	I	87.7	Confident	83.9	Confident	51 Å²	51	77.8 Å²	77.8	26%	0.262	41%	0.412	S	S	.	.	H	α-helix	trans	-62.2	-44.7	177.7	-64.6	169.2	0	0	0	110	V7 E8 A14 L15 M128 I132	V7-I11 HydrophobicContact CG1-CD1 3.69Å; V7-I11 HydrophobicContact CG1-CG1 4.33Å; V7-I11 VanDerWaalsContact O-CG1 3.32Å; V7-I11 WeakPolarHBondContact O-CG1 3.29Å; V7-I11 PolarHBondContact O-N 3.44Å; E8-I11 PolarHBondContact O-N 3.49Å; I11-A14 PolarHBondContact O-N 3.44Å; I11-L15 HydrophobicContact CG2-CD1 3.85Å; I11-L15 HydrophobicContact CG2-CG 4.41Å; I11-L15 WeakPolarHBondContact O-CB 3.29Å; I11-L15 WeakPolarHBondContact O-CG 3.36Å; I11-L15 PolarHBondContact O-N 3.27Å; I11-M128 HydrophobicContact CD1-SD 4.2Å; I11-I132 HydrophobicContact CB-CD1 4.33Å; I11-I132 HydrophobicContact CG2-CD1 3.75Å
12	F	87.6	Confident	85.7	Confident	23 Å²	23	74.1 Å²	74.1	10%	0.101	40%	0.397	C	S	.	.	H	α-helix	trans	-60.3	-47.5	177.6	175.9	-101.4	0	0	0	112	E8 Y10 A14 L15 C16 F109 Y110 Y113	E8-F12 WeakPolarHBondContact O-CB 3.26Å; E8-F12 PolarHBondContact O-N 2.8Å; Y10-F12 VanDerWaalsContact C-N 3.33Å; Y10-F12 PolarHBondContact O-N 2.82Å; F12-A14 PolarHBondContact O-N 3.44Å; F12-L15 PolarHBondContact O-N 3.09Å; F12-C16 WeakPolarHBondContact O-CB 3.36Å; F12-C16 PolarHBondContact O-N 3.5Å; F12-F109 HydrophobicContact CD2-CE1 4.01Å; F12-F109 AromaticContact CE2-CD1 3.96Å; F12-F109 HydrophobicContact CE2-CD1 3.96Å; F12-F109 AromaticContact CE2-CE1 3.44Å; F12-F109 HydrophobicContact CE2-CE1 3.44Å; F12-F109 VanDerWaalsContact CE2-CE1 3.44Å; F12-F109 HydrophobicContact CE2-CZ 4.43Å; F12-F109 HydrophobicContact CZ-CD1 4.23Å; F12-F109 HydrophobicContact CZ-CE1 4.05Å; F12-Y110 AromaticContact CE1-CD2 3.66Å; F12-Y110 HydrophobicContact CE1-CD2 3.66Å; F12-Y110 AromaticContact CE1-CE2 3.87Å; F12-Y110 HydrophobicContact CE1-CE2 3.87Å; F12-Y110 AromaticContact CZ-CD2 3.51Å; F12-Y110 HydrophobicContact CZ-CD2 3.51Å; F12-Y110 HydrophobicContact CZ-CE2 4.1Å; F12-Y110 HydrophobicContact CZ-CG 4.43Å; F12-Y113 AromaticContact CD2-CD1 3.75Å; F12-Y113 HydrophobicContact CD2-CD1 3.75Å; F12-Y113 AromaticContact CD2-CD2 3.65Å; F12-Y113 HydrophobicContact CD2-CD2 3.65Å; F12-Y113 AromaticContact CD2-CE1 3.99Å; F12-Y113 HydrophobicContact CD2-CE1 3.99Å; F12-Y113 AromaticContact CD2-CE2 3.9Å; F12-Y113 HydrophobicContact CD2-CE2 3.9Å; F12-Y113 AromaticContact CD2-CG 3.57Å; F12-Y113 HydrophobicContact CD2-CG 3.57Å; F12-Y113 HydrophobicContact CE1-CD1 4.37Å; F12-Y113 VanDerWaalsContact CE2-CB 3.41Å; F12-Y113 AromaticContact CE2-CD1 3.47Å; F12-Y113 HydrophobicContact CE2-CD1 3.47Å; F12-Y113 VanDerWaalsContact CE2-CD1 3.47Å; F12-Y113 AromaticContact CE2-CD2 3.82Å; F12-Y113 HydrophobicContact CE2-CD2 3.82Å; F12-Y113 HydrophobicContact CE2-CE1 4.15Å; F12-Y113 HydrophobicContact CE2-CE2 4.45Å; F12-Y113 AromaticContact CE2-CG 3.27Å; F12-Y113 HydrophobicContact CE2-CG 3.27Å; F12-Y113 HydrophobicContact CG-CD1 4.32Å; F12-Y113 HydrophobicContact CG-CE1 4.2Å; F12-Y113 HydrophobicContact CG-CE2 4.5Å; F12-Y113 AromaticContact CZ-CD1 3.81Å; F12-Y113 HydrophobicContact CZ-CD1 3.81Å; F12-Y113 HydrophobicContact CZ-CE1 4.48Å; F12-Y113 HydrophobicContact CZ-CG 4.03Å
13	S	89.5	Confident	87.4	Confident	66 Å²	66	67.5 Å²	67.5	46%	0.462	37%	0.366	S	S	.	.	H	α-helix	trans	-61.4	-44.1	177.6	-176.1	0	0	0	0	112.1	S9 Y10 L15 C16 S17	S9-S13 VanDerWaalsContact O-CB 3.31Å; S9-S13 WeakPolarHBondContact O-CB 3.14Å; S9-S13 PolarHBondContact O-N 3.41Å; Y10-S13 PolarHBondContact O-N 2.85Å; S13-L15 PolarHBondContact O-N 3.01Å; S13-C16 PolarHBondContact O-N 3.28Å; S13-S17 WeakPolarHBondContact O-CB 3.4Å; S13-S17 PolarHBondContact O-N 3.27Å; S13-S17 PolarHBondContact O-OG 2.97Å
14	A	92	Very high	88.8	Confident	54 Å²	54	63.7 Å²	63.7	45%	0.446	35%	0.348	S	S	.	.	H	α-helix	trans	-60.1	-45.8	175.6	0	0	0	0	0	111.4	Y10 I11 F12 S17 V18	Y10-A14 WeakPolarHBondContact O-CB 3.47Å; Y10-A14 PolarHBondContact O-N 3.31Å; I11-A14 PolarHBondContact O-N 3.44Å; F12-A14 PolarHBondContact O-N 3.44Å; A14-S17 WeakPolarHBondContact O-CB 3.29Å; A14-S17 PolarHBondContact O-N 3Å; A14-V18 VanDerWaalsContact O-CG2 3.32Å; A14-V18 WeakPolarHBondContact O-CG2 3.23Å; A14-V18 PolarHBondContact O-N 2.9Å
15	L	91.6	Very high	90.3	Very high	52 Å²	52	65.2 Å²	65.2	27%	0.272	36%	0.357	S	S	.	.	H	α-helix	trans	-68.7	-37	179.1	-72.3	172.1	0	0	0	113.2	I11 F12 S13 S17 V18 N19 F109 I132 V136	I11-L15 HydrophobicContact CG2-CD1 3.85Å; I11-L15 HydrophobicContact CG2-CG 4.41Å; I11-L15 WeakPolarHBondContact O-CB 3.29Å; I11-L15 WeakPolarHBondContact O-CG 3.36Å; I11-L15 PolarHBondContact O-N 3.27Å; F12-L15 PolarHBondContact O-N 3.09Å; S13-L15 PolarHBondContact O-N 3.01Å; L15-S17 VanDerWaalsContact C-N 3.28Å; L15-S17 PolarHBondContact O-N 3.16Å; L15-V18 PolarHBondContact O-N 3.44Å; L15-N19 VanDerWaalsContact O-CB 3.27Å; L15-N19 WeakPolarHBondContact O-CB 3.47Å; L15-N19 PolarHBondContact O-N 3.23Å; L15-F109 HydrophobicContact CB-CZ 4Å; L15-I132 HydrophobicContact CD1-CG2 3.07Å; L15-V136 HydrophobicContact CD1-CG2 4.25Å
16	C	91.6	Very high	91.4	Very high	31 Å²	31	62.7 Å²	62.7	21%	0.209	35%	0.346	C	S	.	.	H	α-helix	trans	-60.8	-42.3	172.7	-171	0	0	0	0	110.6	F12 S13 N19 F20 F109	F12-C16 WeakPolarHBondContact O-CB 3.36Å; F12-C16 PolarHBondContact O-N 3.5Å; S13-C16 PolarHBondContact O-N 3.28Å; C16-N19 PolarHBondContact O-N 3.39Å; C16-F20 WeakPolarHBondContact O-CB 3.46Å; C16-F20 PolarHBondContact O-N 3.09Å; C16-F109 HydrophobicContact CB-CD1 4.16Å; C16-F109 HydrophobicContact CB-CE1 3.95Å
17	S	94.1	Very high	92.3	Very high	68 Å²	68	58.7 Å²	58.7	48%	0.476	33%	0.329	S	S	.	.	H	α-helix	trans	-65.9	-43.7	177.2	-56.4	0	0	0	0	112	S13 A14 L15 F20 L21	S13-S17 WeakPolarHBondContact O-CB 3.4Å; S13-S17 PolarHBondContact O-N 3.27Å; S13-S17 PolarHBondContact O-OG 2.97Å; A14-S17 WeakPolarHBondContact O-CB 3.29Å; A14-S17 PolarHBondContact O-N 3Å; L15-S17 VanDerWaalsContact C-N 3.28Å; L15-S17 PolarHBondContact O-N 3.16Å; S17-F20 PolarHBondContact O-N 2.68Å; S17-L21 WeakPolarHBondContact O-CB 3.38Å; S17-L21 PolarHBondContact O-N 3.09Å
18	V	94.8	Very high	93	Very high	81 Å²	81	57.2 Å²	57.2	49%	0.491	32%	0.322	S	S	.	.	H	α-helix	trans	-63.6	-46.9	175.5	170.7	0	0	0	0	110.8	A14 L15 F20 L21 V22	A14-V18 VanDerWaalsContact O-CG2 3.32Å; A14-V18 WeakPolarHBondContact O-CG2 3.23Å; A14-V18 PolarHBondContact O-N 2.9Å; L15-V18 PolarHBondContact O-N 3.44Å; V18-F20 VanDerWaalsContact C-N 3.3Å; V18-F20 PolarHBondContact O-N 3.45Å; V18-L21 PolarHBondContact O-N 3.15Å; V18-V22 HydrophobicContact CG1-CG2 4.18Å; V18-V22 WeakPolarHBondContact O-CB 3.28Å; V18-V22 VanDerWaalsContact O-CG2 3.3Å; V18-V22 WeakPolarHBondContact O-CG2 3.35Å; V18-V22 PolarHBondContact O-N 2.91Å
19	N	93.9	Very high	93.7	Very high	13 Å²	13	61.5 Å²	61.5	7%	0.07	34%	0.34	C	S	.	.	H	α-helix	trans	-58.8	-43.4	177.4	179	57.3	0	0	0	111.3	L15 C16 S23 N105 F109	L15-N19 VanDerWaalsContact O-CB 3.27Å; L15-N19 WeakPolarHBondContact O-CB 3.47Å; L15-N19 PolarHBondContact O-N 3.23Å; C16-N19 PolarHBondContact O-N 3.39Å; N19-S23 WeakPolarHBondContact O-CB 3.46Å; N19-S23 PolarHBondContact O-N 3.05Å; N19-S23 PolarHBondContact O-OG 3.35Å; N19-N105 PolarHBondContact ND2-ND2 3.43Å; N19-F109 HydrophobicContact CB-CD2 4.17Å; N19-F109 HydrophobicContact CB-CE2 4.29Å
20	F	96.1	Very high	94.3	Very high	76 Å²	76	58.1 Å²	58.1	33%	0.333	32%	0.317	S	S	.	.	H	α-helix	trans	-63.7	-48	175.5	-179.3	-122.9	0	0	0	112	C16 S17 V18 S23 C24 F99 V102 C106	C16-F20 WeakPolarHBondContact O-CB 3.46Å; C16-F20 PolarHBondContact O-N 3.09Å; S17-F20 PolarHBondContact O-N 2.68Å; V18-F20 VanDerWaalsContact C-N 3.3Å; V18-F20 PolarHBondContact O-N 3.45Å; F20-S23 PolarHBondContact O-N 3.33Å; F20-C24 WeakPolarHBondContact CE2-SG 3.35Å; F20-C24 WeakPolarHBondContact O-CB 3.34Å; F20-C24 PolarHBondContact O-N 3.16Å; F20-C24 PolarHBondContact O-SG 3.14Å; F20-C24 VanDerWaalsContact O-SG 3.36Å; F20-F99 HydrophobicContact CE2-CZ 4.25Å; F20-F99 HydrophobicContact CZ-CZ 4.15Å; F20-V102 HydrophobicContact CD2-CG1 4.25Å; F20-V102 HydrophobicContact CE2-CG1 4.11Å; F20-C106 WeakPolarHBondContact CD2-SG 3.22Å
21	L	97.4	Very high	94.7	Very high	102 Å²	102	51 Å²	51	53%	0.534	29%	0.291	S	S	.	.	H	α-helix	trans	-59.1	-51	179.3	177.8	62.3	0	0	0	111.7	S17 V18 S23 C24 L25	S17-L21 WeakPolarHBondContact O-CB 3.38Å; S17-L21 PolarHBondContact O-N 3.09Å; V18-L21 PolarHBondContact O-N 3.15Å; L21-S23 VanDerWaalsContact C-N 3.31Å; L21-S23 PolarHBondContact O-N 2.97Å; L21-C24 WeakPolarHBondContact O-CB 3.36Å; L21-C24 PolarHBondContact O-N 3.47Å; L21-L25 HydrophobicContact CD1-CD1 4.47Å; L21-L25 HydrophobicContact CD1-CG 4.43Å; L21-L25 HydrophobicContact CG-CD1 4.34Å; L21-L25 WeakPolarHBondContact O-CG 3.07Å; L21-L25 PolarHBondContact O-N 2.88Å
22	V	96.9	Very high	95.1	Very high	65 Å²	65	56.8 Å²	56.8	39%	0.394	31%	0.309	S	S	.	.	H	α-helix	trans	-59.5	-44.7	178.1	173.9	0	0	0	0	110.5	V18 C24 L25 L26	V18-V22 HydrophobicContact CG1-CG2 4.18Å; V18-V22 WeakPolarHBondContact O-CB 3.28Å; V18-V22 VanDerWaalsContact O-CG2 3.3Å; V18-V22 WeakPolarHBondContact O-CG2 3.35Å; V18-V22 PolarHBondContact O-N 2.91Å; V22-C24 VanDerWaalsContact C-N 3.34Å; V22-C24 PolarHBondContact O-N 3.23Å; V22-L25 PolarHBondContact O-N 3.43Å; V22-L26 HydrophobicContact CG1-CD1 4.05Å; V22-L26 HydrophobicContact CG1-CG 4.49Å; V22-L26 WeakPolarHBondContact O-CG 3.32Å; V22-L26 PolarHBondContact O-N 3.01Å
23	S	97.4	Very high	95.4	Very high	0 Å²	0	57.7 Å²	57.7	0%	0	32%	0.316	C	S	.	.	H	α-helix	trans	-62.5	-40.2	177.5	-57.8	0	0	0	0	111.7	N19 F20 L21 L26 F27 N105 Y145 F149	N19-S23 WeakPolarHBondContact O-CB 3.46Å; N19-S23 PolarHBondContact O-N 3.05Å; N19-S23 PolarHBondContact O-OG 3.35Å; F20-S23 PolarHBondContact O-N 3.33Å; L21-S23 VanDerWaalsContact C-N 3.31Å; L21-S23 PolarHBondContact O-N 2.97Å; S23-L26 PolarHBondContact O-N 2.9Å; S23-F27 WeakPolarHBondContact O-CB 3.27Å; S23-F27 PolarHBondContact O-N 3.4Å; S23-N105 PolarHBondContact OG-ND2 2.97Å; S23-Y145 PolarHBondContact OG-OH 2.89Å; S23-F149 VanDerWaalsContact O-CE1 3.3Å; S23-F149 WeakPolarHBondContact O-CE1 3.05Å
24	C	98.1	Very high	95.7	Very high	31 Å²	31	55.6 Å²	55.6	21%	0.209	30%	0.299	C	S	.	.	H	α-helix	trans	-64.9	-39.6	175.2	-77	0	0	0	0	112.9	F20 L21 V22 S28	F20-C24 WeakPolarHBondContact CE2-SG 3.35Å; F20-C24 WeakPolarHBondContact O-CB 3.34Å; F20-C24 PolarHBondContact O-N 3.16Å; F20-C24 PolarHBondContact O-SG 3.14Å; F20-C24 VanDerWaalsContact O-SG 3.36Å; L21-C24 WeakPolarHBondContact O-CB 3.36Å; L21-C24 PolarHBondContact O-N 3.47Å; V22-C24 VanDerWaalsContact C-N 3.34Å; V22-C24 PolarHBondContact O-N 3.23Å; C24-S28 VanDerWaalsContact O-CB 3.27Å; C24-S28 WeakPolarHBondContact O-CB 3.47Å; C24-S28 PolarHBondContact O-N 3.46Å
25	L	97.8	Very high	95.7	Very high	111 Å²	111	61.7 Å²	61.7	58%	0.581	31%	0.311	S	S	*	.	H	α-helix	trans	-65.4	-45.8	176.7	-68.4	174.4	0	0	0	111.4	L21 V22 S28 K29	L21-L25 HydrophobicContact CD1-CD1 4.47Å; L21-L25 HydrophobicContact CD1-CG 4.43Å; L21-L25 HydrophobicContact CG-CD1 4.34Å; L21-L25 WeakPolarHBondContact O-CG 3.07Å; L21-L25 PolarHBondContact O-N 2.88Å; V22-L25 PolarHBondContact O-N 3.43Å; L25-S28 PolarHBondContact O-N 3.47Å; L25-K29 PolarHBondContact O-N 3.27Å
26	L	97.6	Very high	95.8	Very high	49 Å²	49	64.8 Å²	64.8	26%	0.257	33%	0.328	S	S	.	.	H	α-helix	trans	-64.6	-45.6	175.8	-69.5	175.1	0	0	0	111.6	V22 S23 S28 K29 M30 Y145 F149 I456	V22-L26 HydrophobicContact CG1-CD1 4.05Å; V22-L26 HydrophobicContact CG1-CG 4.49Å; V22-L26 WeakPolarHBondContact O-CG 3.32Å; V22-L26 PolarHBondContact O-N 3.01Å; S23-L26 PolarHBondContact O-N 2.9Å; L26-S28 VanDerWaalsContact C-N 3.34Å; L26-S28 PolarHBondContact O-N 2.85Å; L26-K29 PolarHBondContact O-N 3.05Å; L26-K29 VanDerWaalsContact O-N 3.14Å; L26-M30 PolarHBondContact O-N 3Å; L26-Y145 HydrophobicContact CD1-CE1 3.85Å; L26-F149 HydrophobicContact CB-CE1 3.93Å; L26-F149 HydrophobicContact CB-CE2 4.27Å; L26-F149 HydrophobicContact CB-CZ 3.71Å; L26-F149 HydrophobicContact CD1-CE2 4.37Å; L26-F149 HydrophobicContact CD1-CZ 3.92Å; L26-F149 HydrophobicContact CG-CZ 4.49Å; L26-I456 HydrophobicContact CD1-CD1 4.1Å
27	F	97.9	Very high	96	Very high	21 Å²	21	65.1 Å²	65.1	9%	0.092	33%	0.329	C	S	.	.	H	α-helix	trans	-54.7	-48.2	174.4	169	-107.1	0	0	0	111.8	S23 K29 M30 T31 A95 R98 F99 V102 F149	S23-F27 WeakPolarHBondContact O-CB 3.27Å; S23-F27 PolarHBondContact O-N 3.4Å; F27-K29 VanDerWaalsContact C-N 3.33Å; F27-K29 PolarHBondContact O-N 3.38Å; F27-M30 PolarHBondContact O-N 3.31Å; F27-T31 WeakPolarHBondContact CE2-OG1 3.25Å; F27-T31 WeakPolarHBondContact CZ-OG1 3.42Å; F27-T31 VanDerWaalsContact O-CB 3.22Å; F27-T31 WeakPolarHBondContact O-CB 3.08Å; F27-T31 PolarHBondContact O-N 3.22Å; F27-T31 PolarHBondContact O-OG1 3.16Å; F27-A95 HydrophobicContact CZ-CB 4.49Å; F27-A95 VanDerWaalsContact CZ-O 3.31Å; F27-A95 WeakPolarHBondContact CZ-O 3.46Å; F27-R98 HydrophobicContact CE2-CB 3.55Å; F27-R98 HydrophobicContact CZ-CB 4.25Å; F27-F99 HydrophobicContact CD1-CD2 4.08Å; F27-F99 HydrophobicContact CE1-CB 4.32Å; F27-F99 AromaticContact CE1-CD2 3.84Å; F27-F99 HydrophobicContact CE1-CD2 3.84Å; F27-F99 HydrophobicContact CZ-CB 4.11Å; F27-F99 HydrophobicContact CZ-CD2 4.41Å; F27-V102 HydrophobicContact CB-CG2 4.01Å; F27-V102 HydrophobicContact CD2-CG2 3.9Å; F27-V102 HydrophobicContact CG-CG2 3.86Å; F27-F149 HydrophobicContact CB-CD1 3.84Å; F27-F149 HydrophobicContact CB-CE1 4.26Å
28	S	97.5	Very high	96	Very high	41 Å²	41	62.2 Å²	62.2	29%	0.287	31%	0.308	S	S	.	.	H	α-helix	trans	-59.9	-43.9	177	-179.6	0	0	0	0	111.2	C24 L25 L26 R32	C24-S28 VanDerWaalsContact O-CB 3.27Å; C24-S28 WeakPolarHBondContact O-CB 3.47Å; C24-S28 PolarHBondContact O-N 3.46Å; L25-S28 PolarHBondContact O-N 3.47Å; L26-S28 VanDerWaalsContact C-N 3.34Å; L26-S28 PolarHBondContact O-N 2.85Å; S28-R32 WeakPolarHBondContact O-CB 3.39Å; S28-R32 WeakPolarHBondContact O-CD 3.44Å; S28-R32 WeakPolarHBondContact O-CG 3.37Å; S28-R32 PolarHBondContact O-N 3.31Å; S28-R32 PolarHBondContact OG-NE 3.48Å
29	K	97.3	Very high	95.8	Very high	115 Å²	115	58.9 Å²	58.9	50%	0.5	29%	0.287	S	S	.	.	H	α-helix	trans	-65.1	-49.3	177.8	-174.2	68.2	177	-174.9	0	112.2	L25 L26 F27 R32 V33 I460	L25-K29 PolarHBondContact O-N 3.27Å; L26-K29 PolarHBondContact O-N 3.05Å; L26-K29 VanDerWaalsContact O-N 3.14Å; F27-K29 VanDerWaalsContact C-N 3.33Å; F27-K29 PolarHBondContact O-N 3.38Å; K29-R32 PolarHBondContact O-N 3.47Å; K29-V33 VanDerWaalsContact O-CG2 3.26Å; K29-V33 WeakPolarHBondContact O-CG2 3.41Å; K29-V33 PolarHBondContact O-N 3.45Å; K29-I460 HydrophobicContact CG-CD1 3.82Å
30	M	96	Very high	95.8	Very high	2 Å²	2	60.9 Å²	60.9	1%	0.01	30%	0.298	C	S	.	.	H	α-helix	trans	-63.5	-44.1	-179.9	-73.4	-176.8	72.6	0	0	111.6	L26 F27 R32 V33 Q34 F146 F149 I456 F459 I460	L26-M30 PolarHBondContact O-N 3Å; F27-M30 PolarHBondContact O-N 3.31Å; M30-R32 VanDerWaalsContact C-N 3.33Å; M30-R32 PolarHBondContact O-N 3.42Å; M30-V33 PolarHBondContact O-N 3.04Å; M30-Q34 PolarHBondContact O-N 2.87Å; M30-F146 HydrophobicContact CE-CE2 4.23Å; M30-F146 HydrophobicContact CE-CZ 4.29Å; M30-F149 HydrophobicContact CE-CB 3.97Å; M30-F149 HydrophobicContact CE-CD2 4.33Å; M30-F149 HydrophobicContact SD-CB 3.54Å; M30-F149 VanDerWaalsContact SD-CB 3.54Å; M30-F149 HydrophobicContact SD-CD2 3.37Å; M30-F149 WeakPolarHBondContact SD-CD2 3.4Å; M30-F149 HydrophobicContact SD-CE2 4.25Å; M30-F149 HydrophobicContact SD-CG 3.63Å; M30-I456 HydrophobicContact SD-CG1 4.44Å; M30-I456 HydrophobicContact SD-CG2 4.33Å; M30-F459 HydrophobicContact CE-CD1 3.52Å; M30-F459 HydrophobicContact CE-CE1 3.66Å; M30-F459 HydrophobicContact CE-CG 4.07Å; M30-F459 HydrophobicContact CE-CZ 4.32Å; M30-F459 HydrophobicContact CG-CD1 4.45Å; M30-I460 HydrophobicContact CG-CD1 4.01Å; M30-I460 HydrophobicContact CG-CG1 4.18Å
31	T	95.7	Very high	95.8	Very high	19 Å²	19	57.3 Å²	57.3	12%	0.117	28%	0.282	C	S	.	.	H	α-helix	trans	-65.2	-35.2	178.5	-61.1	0	0	0	0	112.4	F27 V33 Q34 R35 A95	F27-T31 WeakPolarHBondContact CE2-OG1 3.25Å; F27-T31 WeakPolarHBondContact CZ-OG1 3.42Å; F27-T31 VanDerWaalsContact O-CB 3.22Å; F27-T31 WeakPolarHBondContact O-CB 3.08Å; F27-T31 PolarHBondContact O-N 3.22Å; F27-T31 PolarHBondContact O-OG1 3.16Å; T31-V33 VanDerWaalsContact C-N 3.32Å; T31-Q34 CarbonylContact O-C 3.31Å; T31-Q34 VanDerWaalsContact O-C 3.31Å; T31-R35 WeakPolarHBondContact O-CA 3.45Å; T31-R35 WeakPolarHBondContact O-CG 3.3Å; T31-R35 PolarHBondContact O-N 3.47Å; T31-A95 HydrophobicContact CG2-CB 3.83Å
32	R	95.3	Very high	95.7	Very high	173 Å²	173	56.6 Å²	56.6	65%	0.653	28%	0.278	S	S	*	.	H	α-helix	trans	-66.1	-36.3	174.5	-76.4	171.3	-169.7	-165	1.4	112.6	S28 K29 M30	S28-R32 WeakPolarHBondContact O-CB 3.39Å; S28-R32 WeakPolarHBondContact O-CD 3.44Å; S28-R32 WeakPolarHBondContact O-CG 3.37Å; S28-R32 PolarHBondContact O-N 3.31Å; S28-R32 PolarHBondContact OG-NE 3.48Å; K29-R32 PolarHBondContact O-N 3.47Å; M30-R32 VanDerWaalsContact C-N 3.33Å; M30-R32 PolarHBondContact O-N 3.42Å
33	V	94.8	Very high	95.6	Very high	41 Å²	41	56.6 Å²	56.6	25%	0.248	27%	0.273	C	S	.	.	H	α-helix	trans	-80.5	-32.9	-176.5	169.8	0	0	0	0	111.9	K29 M30 T31 I460 R474	K29-V33 VanDerWaalsContact O-CG2 3.26Å; K29-V33 WeakPolarHBondContact O-CG2 3.41Å; K29-V33 PolarHBondContact O-N 3.45Å; M30-V33 PolarHBondContact O-N 3.04Å; T31-V33 VanDerWaalsContact C-N 3.32Å; V33-I460 HydrophobicContact CG1-CG2 4.42Å; V33-I460 HydrophobicContact CG2-CG2 4.08Å; V33-R474 PolarHBondContact O-NH2 3Å
34	Q	94.9	Very high	95.6	Very high	23 Å²	23	57.5 Å²	57.5	11%	0.107	28%	0.277	C	S	.	.			trans	-127.7	85.1	176.1	-174.8	60	28.4	0	0	109	M30 T31 D36 Y38 R98 F459	M30-Q34 PolarHBondContact O-N 2.87Å; T31-Q34 CarbonylContact O-C 3.31Å; T31-Q34 VanDerWaalsContact O-C 3.31Å; Q34-D36 PolarHBondContact NE2-O 2.99Å; Q34-Y38 HydrophobicContact CG-CD2 4.43Å; Q34-Y38 HydrophobicContact CG-CG 4.11Å; Q34-R98 PolarHBondContact O-NH1 3.18Å; Q34-R98 PolarHBondContact O-NH2 3Å; Q34-F459 HydrophobicContact CB-CE1 4.08Å; Q34-F459 HydrophobicContact CB-CZ 3.99Å; Q34-F459 HydrophobicContact CG-CZ 4.15Å
35	R	93.5	Very high	95.5	Very high	182 Å²	182	56 Å²	56	69%	0.687	27%	0.267	S	S	*	.			trans	-76	-40.9	-176.7	-66.8	-178.6	-177.2	-173.9	-0.9	112.3	T31	T31-R35 WeakPolarHBondContact O-CA 3.45Å; T31-R35 WeakPolarHBondContact O-CG 3.3Å; T31-R35 PolarHBondContact O-N 3.47Å
36	D	93.4	Very high	95.4	Very high	117 Å²	117	52.7 Å²	52.7	63%	0.626	25%	0.252	S	S	*	.	S	Bend	trans	-77.3	153	-178	-56.5	-56.8	0	0	0	111.2	Q34 Y38 R98	Q34-D36 PolarHBondContact NE2-O 2.99Å; D36-Y38 PolarHBondContact O-N 2.92Å; D36-R98 PolarHBondContact O-NH2 3.11Å; D36-R98 VanDerWaalsContact O-NH2 3.08Å
37	P	94.9	Very high	95.4	Very high	37 Å²	37	50.3 Å²	50.3	24%	0.24	24%	0.24	C	C	.	.			trans	-51.1	129.2	172.4	-25	34.9	0	0	0	110.9	E41 I42 V45	P37-E41 HydrophobicContact CB-CB 3.77Å; P37-E41 WeakPolarHBondContact CB-O 3.26Å; P37-I42 HydrophobicContact CB-CG2 4.3Å; P37-V45 HydrophobicContact CB-CB 4.23Å; P37-V45 HydrophobicContact CB-CG2 4.23Å; P37-V45 HydrophobicContact CG-CB 3.92Å; P37-V45 HydrophobicContact CG-CG1 3.92Å; P37-V45 HydrophobicContact CG-CG2 4.19Å
38	Y	94.2	Very high	95.3	Very high	7 Å²	7	49.3 Å²	49.3	3%	0.027	24%	0.235	C	C	.	.			trans	-114	134.6	-178	-170.4	-117.7	0	0	0	110.4	Q34 D36 D40 E41 R356 F459 R474 M476	Q34-Y38 HydrophobicContact CG-CD2 4.43Å; Q34-Y38 HydrophobicContact CG-CG 4.11Å; D36-Y38 PolarHBondContact O-N 2.92Å; Y38-D40 PolarHBondContact O-N 3.45Å; Y38-E41 PolarHBondContact N-OE2 3.12Å; Y38-E41 VanDerWaalsContact O-CB 3.23Å; Y38-E41 WeakPolarHBondContact O-CB 3.36Å; Y38-E41 VanDerWaalsContact O-CG 3.31Å; Y38-E41 WeakPolarHBondContact O-CG 3.48Å; Y38-E41 PolarHBondContact O-N 2.89Å; Y38-E41 VanDerWaalsContact O-N 3.14Å; Y38-R356 WeakPolarHBondContact OH-CD 3.24Å; Y38-F459 AromaticContact CD1-CE2 3.74Å; Y38-F459 HydrophobicContact CD1-CE2 3.74Å; Y38-F459 HydrophobicContact CD1-CZ 4.21Å; Y38-F459 AromaticContact CE1-CE2 3.74Å; Y38-F459 HydrophobicContact CE1-CE2 3.74Å; Y38-R474 HydrophobicContact CE1-CB 4.31Å; Y38-R474 WeakPolarHBondContact OH-CA 3.43Å; Y38-R474 PolarHBondContact OH-N 2.89Å; Y38-R474 PolarHBondContact OH-O 3.25Å; Y38-M476 HydrophobicContact CD1-SD 4.16Å; Y38-M476 HydrophobicContact CE1-CG 4.49Å; Y38-M476 HydrophobicContact CE1-SD 3.72Å
39	M	92.3	Very high	95.2	Very high	12 Å²	12	50.6 Å²	50.6	6%	0.059	24%	0.237	C	C	.	.	T	Hydrogen-bonded Turn	trans	59.7	-128.3	176.8	-53.4	-70.9	-62.8	0	0	112	E41 I42 Y152 D354 R356 H357 M476	M39-E41 PolarHBondContact O-N 3.25Å; M39-E41 VanDerWaalsContact O-N 3.08Å; M39-I42 WeakPolarHBondContact O-CB 3.49Å; M39-I42 WeakPolarHBondContact O-CG1 3.39Å; M39-I42 WeakPolarHBondContact O-CG2 3.46Å; M39-I42 PolarHBondContact O-N 2.83Å; M39-Y152 VanDerWaalsContact CB-OH 3.26Å; M39-Y152 WeakPolarHBondContact CB-OH 3.48Å; M39-D354 VanDerWaalsContact CE-OD2 3.32Å; M39-D354 WeakPolarHBondContact CE-OD2 3.42Å; M39-R356 HydrophobicContact CE-CB 4.39Å; M39-R356 VanDerWaalsContact CE-NH2 3.25Å; M39-R356 HydrophobicContact SD-CB 4.36Å; M39-R356 WeakPolarHBondContact SD-CD 3.33Å; M39-R356 HydrophobicContact SD-CG 4.49Å; M39-R356 PolarHBondContact SD-NE 2.96Å; M39-R356 PolarHBondContact SD-NH1 2.98Å; M39-R356 PolarHBondContact SD-NH2 3.46Å; M39-R356 VanDerWaalsContact SD-NH2 3.4Å; M39-H357 WeakPolarHBondContact CE-CE1 3.32Å; M39-M476 HydrophobicContact CB-SD 4.33Å; M39-M476 HydrophobicContact CE-SD 4.24Å; M39-M476 HydrophobicContact CG-SD 3.5Å; M39-M476 WeakPolarHBondContact CG-SD 3.33Å; M39-M476 HydrophobicContact SD-SD 4.31Å
40	D	92.6	Very high	95	Very high	55 Å²	55	48.7 Å²	48.7	29%	0.294	23%	0.226	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.5	-19.7	-178.6	-52.3	-33.6	0	0	0	111.8	Y38 I42 F43 H44 Y152 R420	Y38-D40 PolarHBondContact O-N 3.45Å; D40-I42 PolarHBondContact O-N 3.48Å; D40-I42 VanDerWaalsContact O-N 3.13Å; D40-F43 PolarHBondContact O-N 3.33Å; D40-H44 PolarHBondContact O-CD2 3.36Å; D40-H44 PolarHBondContact O-N 3.2Å; D40-Y152 HydrophobicContact CB-CE1 4.16Å; D40-Y152 WeakPolarHBondContact CB-OH 3.19Å; D40-Y152 VanDerWaalsContact CG-OH 3.27Å; D40-Y152 PolarHBondContact N-OH 2.9Å; D40-Y152 VanDerWaalsContact OD2-CE1 3.24Å; D40-Y152 WeakPolarHBondContact OD2-CE1 3.38Å; D40-Y152 PolarHBondContact OD2-OH 3.46Å; D40-R420 IonicContact OD2-NH1 2.76Å
41	E	96.2	Very high	95	Very high	0 Å²	0	49.4 Å²	49.4	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-59.2	-24.6	174.1	-61.4	-175.5	121.1	0	0	112.4	P37 Y38 M39 F43 H44 V45 R98 Y151 Y152	P37-E41 HydrophobicContact CB-CB 3.77Å; P37-E41 WeakPolarHBondContact CB-O 3.26Å; Y38-E41 PolarHBondContact N-OE2 3.12Å; Y38-E41 VanDerWaalsContact O-CB 3.23Å; Y38-E41 WeakPolarHBondContact O-CB 3.36Å; Y38-E41 VanDerWaalsContact O-CG 3.31Å; Y38-E41 WeakPolarHBondContact O-CG 3.48Å; Y38-E41 PolarHBondContact O-N 2.89Å; Y38-E41 VanDerWaalsContact O-N 3.14Å; M39-E41 PolarHBondContact O-N 3.25Å; M39-E41 VanDerWaalsContact O-N 3.08Å; E41-F43 PolarHBondContact O-N 3.3Å; E41-H44 PolarHBondContact O-N 3.46Å; E41-V45 HydrophobicContact CB-CG2 3.96Å; E41-V45 VanDerWaalsContact O-CB 3.3Å; E41-V45 WeakPolarHBondContact O-CB 3.48Å; E41-V45 PolarHBondContact O-N 3.5Å; E41-R98 WeakPolarHBondContact OE1-CG 3.48Å; E41-R98 IonicContact OE1-CZ 2.8Å; E41-R98 IonicContact OE1-NE 2.7Å; E41-R98 PolarHBondContact OE1-NE 2.92Å; E41-R98 IonicContact OE1-NH2 3.45Å; E41-R98 IonicContact OE2-CZ 3.76Å; E41-R98 IonicContact OE2-NE 3.41Å; E41-R98 PolarHBondContact OE2-NE 3.41Å; E41-R98 IonicContact OE2-NH2 3.87Å; E41-R98 PolarHBondContact OE2-NH2 3.36Å; E41-Y151 VanDerWaalsContact OE1-CB 3.23Å; E41-Y151 WeakPolarHBondContact OE1-CB 3.5Å; E41-Y151 PolarHBondContact OE1-N 3.42Å; E41-Y152 HydrophobicContact CG-CD2 4.15Å; E41-Y152 HydrophobicContact CG-CE2 3.86Å
42	I	95	Very high	94.8	Very high	88 Å²	88	48.9 Å²	48.9	45%	0.451	23%	0.226	S	C	.	.	H	α-helix	trans	-59.9	-25.5	174.9	74.4	-170	0	0	0	111.9	P37 M39 D40 P46	P37-I42 HydrophobicContact CB-CG2 4.3Å; M39-I42 WeakPolarHBondContact O-CB 3.49Å; M39-I42 WeakPolarHBondContact O-CG1 3.39Å; M39-I42 WeakPolarHBondContact O-CG2 3.46Å; M39-I42 PolarHBondContact O-N 2.83Å; D40-I42 PolarHBondContact O-N 3.48Å; D40-I42 VanDerWaalsContact O-N 3.13Å; I42-P46 WeakPolarHBondContact O-CD 3.45Å; I42-P46 VanDerWaalsContact O-CG 3.24Å; I42-P46 WeakPolarHBondContact O-CG 3.22Å
43	F	95.6	Very high	94.6	Very high	65 Å²	65	48.6 Å²	48.6	29%	0.285	23%	0.229	S	C	.	.	H	α-helix	trans	-95.5	-44.8	173.4	-51.9	-68.2	0	0	0	110.9	D40 E41 Q47 M62 I63	D40-F43 PolarHBondContact O-N 3.33Å; E41-F43 PolarHBondContact O-N 3.3Å; F43-Q47 WeakPolarHBondContact O-CB 3.49Å; F43-Q47 PolarHBondContact O-N 2.94Å; F43-M62 HydrophobicContact CD1-CB 3.66Å; F43-M62 HydrophobicContact CD1-CG 4.18Å; F43-M62 HydrophobicContact CE1-CB 3.64Å; F43-M62 HydrophobicContact CE1-CG 3.74Å; F43-M62 HydrophobicContact CG-CB 4.13Å; F43-M62 HydrophobicContact CZ-CB 4.08Å; F43-M62 HydrophobicContact CZ-CG 4.26Å; F43-I63 HydrophobicContact CB-CG1 3.94Å
44	H	96.9	Very high	94.4	Very high	18 Å²	18	48.9 Å²	48.9	8%	0.083	24%	0.241	C	C	.	.	H	α-helix	trans	-69.3	-39.4	-174.5	-66.2	-73.4	0	0	0	113.8	D40 E41 A48 Y70 Y151	D40-H44 PolarHBondContact O-CD2 3.36Å; D40-H44 PolarHBondContact O-N 3.2Å; E41-H44 PolarHBondContact O-N 3.46Å; H44-A48 PolarHBondContact O-N 3.14Å; H44-Y70 HydrophobicContact CB-CE1 3.92Å; H44-Y70 AromaticContact ND1-CE1 3.79Å; H44-Y70 AromaticContact ND1-CZ 3.57Å; H44-Y70 PolarHBondContact ND1-OH 2.92Å; H44-Y70 WeakPolarHBondContact O-CE1 3.43Å; H44-Y151 HydrophobicContact CB-CD1 3.93Å; H44-Y151 HydrophobicContact CB-CE1 4.24Å
45	V	96.6	Very high	94.4	Very high	1 Å²	1	52.5 Å²	52.5	1%	0.006	26%	0.256	C	S	.	.	H	α-helix	trans	-69.7	-51.1	-176.7	169.7	0	0	0	0	111.8	P37 E41 Q47 A48 Q49 T94 L97 Y151	P37-V45 HydrophobicContact CB-CB 4.23Å; P37-V45 HydrophobicContact CB-CG2 4.23Å; P37-V45 HydrophobicContact CG-CB 3.92Å; P37-V45 HydrophobicContact CG-CG1 3.92Å; P37-V45 HydrophobicContact CG-CG2 4.19Å; E41-V45 HydrophobicContact CB-CG2 3.96Å; E41-V45 VanDerWaalsContact O-CB 3.3Å; E41-V45 WeakPolarHBondContact O-CB 3.48Å; E41-V45 PolarHBondContact O-N 3.5Å; V45-Q47 PolarHBondContact O-N 3.12Å; V45-A48 PolarHBondContact O-N 3.36Å; V45-Q49 HydrophobicContact CG1-CG 4.46Å; V45-Q49 WeakPolarHBondContact O-CG 3.22Å; V45-Q49 PolarHBondContact O-N 3.5Å; V45-T94 HydrophobicContact CG2-CG2 4.1Å; V45-L97 HydrophobicContact CB-CD1 4.42Å; V45-L97 HydrophobicContact CG1-CD1 3.94Å; V45-L97 HydrophobicContact CG2-CD1 4.37Å; V45-Y151 HydrophobicContact CG2-CD1 3.94Å; V45-Y151 HydrophobicContact CG2-CG 4.46Å
46	P	96.1	Very high	94.4	Very high	40 Å²	40	48.5 Å²	48.5	26%	0.26	24%	0.244	S	C	.	.	H	α-helix	trans	-59.3	-37.2	175.7	-26.5	37.6	0	0	0	112.5	I42 Q49 R50	I42-P46 WeakPolarHBondContact O-CD 3.45Å; I42-P46 VanDerWaalsContact O-CG 3.24Å; I42-P46 WeakPolarHBondContact O-CG 3.22Å; P46-Q49 PolarHBondContact O-N 2.98Å; P46-R50 WeakPolarHBondContact O-CG 3.23Å; P46-R50 PolarHBondContact O-N 3.12Å
47	Q	96.7	Very high	94.5	Very high	0 Å²	0	50.9 Å²	50.9	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-62.2	-47.6	176.1	-174.1	60	36.4	0	0	112.3	F43 V45 Q49 R50 Y51 E58 W59 D60 I63 Y70	F43-Q47 WeakPolarHBondContact O-CB 3.49Å; F43-Q47 PolarHBondContact O-N 2.94Å; V45-Q47 PolarHBondContact O-N 3.12Å; Q47-Q49 VanDerWaalsContact C-N 3.27Å; Q47-Q49 PolarHBondContact O-N 3.16Å; Q47-R50 WeakPolarHBondContact O-CB 3.42Å; Q47-R50 PolarHBondContact O-N 3.31Å; Q47-Y51 PolarHBondContact O-N 3.03Å; Q47-E58 PolarHBondContact NE2-O 3.13Å; Q47-W59 HydrophobicContact CG-CE3 4.43Å; Q47-W59 HydrophobicContact CG-CZ3 4.38Å; Q47-D60 VanDerWaalsContact OE1-N 3.1Å; Q47-I63 HydrophobicContact CB-CD1 3.59Å; Q47-I63 HydrophobicContact CG-CD1 3.55Å; Q47-Y70 HydrophobicContact CB-CE1 4.31Å; Q47-Y70 HydrophobicContact CB-CE2 4.23Å; Q47-Y70 HydrophobicContact CG-CD2 3.82Å; Q47-Y70 HydrophobicContact CG-CE1 4.38Å; Q47-Y70 HydrophobicContact CG-CE2 3.48Å; Q47-Y70 VanDerWaalsContact CG-CE2 3.48Å; Q47-Y70 HydrophobicContact CG-CG 4.39Å
48	A	95.6	Very high	94.4	Very high	0 Å²	0	52.6 Å²	52.6	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-60.6	-38.2	175.2	0	0	0	0	0	112	H44 V45 R50 Y51 C52 Y70 L97 Y151	H44-A48 PolarHBondContact O-N 3.14Å; V45-A48 PolarHBondContact O-N 3.36Å; A48-R50 PolarHBondContact O-N 3.09Å; A48-Y51 PolarHBondContact O-N 3.37Å; A48-C52 PolarHBondContact O-N 2.97Å; A48-C52 PolarHBondContact O-SG 3.42Å; A48-C52 VanDerWaalsContact O-SG 3.37Å; A48-Y70 HydrophobicContact CB-CD1 3.82Å; A48-Y70 HydrophobicContact CB-CG 4.49Å; A48-L97 HydrophobicContact CB-CD1 3.81Å; A48-L97 HydrophobicContact CB-CD2 3.76Å; A48-L97 HydrophobicContact CB-CG 4.45Å; A48-Y151 HydrophobicContact CB-CE1 3.83Å
49	Q	94.8	Very high	94.5	Very high	67 Å²	67	55.8 Å²	55.8	31%	0.313	27%	0.274	S	S	.	.	H	α-helix	trans	-66.5	-33.2	176.9	-71.8	174	-11.4	0	0	113	V45 P46 Q47 C52 K53 C92 L97	V45-Q49 HydrophobicContact CG1-CG 4.46Å; V45-Q49 WeakPolarHBondContact O-CG 3.22Å; V45-Q49 PolarHBondContact O-N 3.5Å; P46-Q49 PolarHBondContact O-N 2.98Å; Q47-Q49 VanDerWaalsContact C-N 3.27Å; Q47-Q49 PolarHBondContact O-N 3.16Å; Q49-C52 WeakPolarHBondContact O-CB 3.42Å; Q49-C52 PolarHBondContact O-N 2.8Å; Q49-K53 WeakPolarHBondContact O-CG 3.42Å; Q49-K53 PolarHBondContact O-N 3.36Å; Q49-C92 HydrophobicContact CG-CB 4.43Å; Q49-C92 WeakPolarHBondContact CG-O 3.33Å; Q49-C92 PolarHBondContact NE2-O 3.01Å; Q49-L97 HydrophobicContact CG-CD1 4.42Å
50	R	94.6	Very high	94.5	Very high	75 Å²	75	56.7 Å²	56.7	28%	0.283	28%	0.279	S	S	.	.	H	α-helix	trans	-62.6	-46.3	170.5	-69.4	172.6	-172.5	115.1	3.7	110.9	P46 Q47 A48 C52 K53 G54 K55 E58	P46-R50 WeakPolarHBondContact O-CG 3.23Å; P46-R50 PolarHBondContact O-N 3.12Å; Q47-R50 WeakPolarHBondContact O-CB 3.42Å; Q47-R50 PolarHBondContact O-N 3.31Å; A48-R50 PolarHBondContact O-N 3.09Å; R50-C52 VanDerWaalsContact C-N 3.31Å; R50-C52 PolarHBondContact O-N 2.86Å; R50-K53 CarbonylContact O-C 3.58Å; R50-K53 WeakPolarHBondContact O-CA 3.28Å; R50-K53 WeakPolarHBondContact O-CB 3.26Å; R50-K53 PolarHBondContact O-N 3.47Å; R50-G54 PolarHBondContact O-N 3.32Å; R50-K55 HydrophobicContact CB-CB 4.28Å; R50-K55 WeakPolarHBondContact O-CB 3.46Å; R50-K55 PolarHBondContact O-N 3.05Å; R50-E58 WeakPolarHBondContact CD-OE2 3.48Å; R50-E58 IonicContact NE-OE2 2.64Å
51	Y	94.6	Very high	94.5	Very high	17 Å²	17	58.1 Å²	58.1	7%	0.067	29%	0.291	C	S	.	.	H	α-helix	trans	-63.8	-37.7	176.8	-77.4	19.6	0	0	0	111.7	Q47 A48 K53 G54 K55 F56 W59 P67 Y70 L71	Q47-Y51 PolarHBondContact O-N 3.03Å; A48-Y51 PolarHBondContact O-N 3.37Å; Y51-K53 PolarHBondContact O-N 3.35Å; Y51-G54 PolarHBondContact O-N 3.1Å; Y51-K55 WeakPolarHBondContact CD1-O 3.42Å; Y51-F56 HydrophobicContact CD1-CD1 4.09Å; Y51-F56 AromaticContact CD2-CD1 3.67Å; Y51-F56 HydrophobicContact CD2-CD1 3.67Å; Y51-F56 AromaticContact CD2-CE1 3.84Å; Y51-F56 HydrophobicContact CD2-CE1 3.84Å; Y51-F56 HydrophobicContact CE1-CD1 4.39Å; Y51-F56 HydrophobicContact CE2-CD1 4.01Å; Y51-F56 AromaticContact CG-CD1 3.71Å; Y51-F56 HydrophobicContact CG-CD1 3.71Å; Y51-F56 AromaticContact CG-CE1 3.91Å; Y51-F56 HydrophobicContact CG-CE1 3.91Å; Y51-W59 WeakPolarHBondContact OH-CZ3 3.38Å; Y51-P67 HydrophobicContact CE2-CB 4.06Å; Y51-Y70 HydrophobicContact CD2-CG 4.5Å; Y51-Y70 HydrophobicContact CE2-CD2 4.23Å; Y51-L71 HydrophobicContact CD2-CD2 4.18Å; Y51-L71 HydrophobicContact CE2-CD2 4.03Å; Y51-L71 HydrophobicContact CE2-CG 4.39Å
52	C	91.6	Very high	94.2	Very high	8 Å²	8	62.6 Å²	62.6	5%	0.054	31%	0.313	C	S	.	.	H	α-helix	trans	-59.4	-26.6	170.8	-73.4	0	0	0	0	113.7	A48 Q49 R50 G54 K78 C92	A48-C52 PolarHBondContact O-N 2.97Å; A48-C52 PolarHBondContact O-SG 3.42Å; A48-C52 VanDerWaalsContact O-SG 3.37Å; Q49-C52 WeakPolarHBondContact O-CB 3.42Å; Q49-C52 PolarHBondContact O-N 2.8Å; R50-C52 VanDerWaalsContact C-N 3.31Å; R50-C52 PolarHBondContact O-N 2.86Å; C52-G54 VanDerWaalsContact C-N 3.28Å; C52-K78 WeakPolarHBondContact O-CE 3.37Å; C52-K78 PolarHBondContact O-NZ 3.26Å; C52-C92 HydrophobicContact CB-CB 3.67Å; C52-C92 WeakPolarHBondContact CB-SG 3.13Å; C52-C92 WeakPolarHBondContact SG-CB 3.21Å; C52-C92 CovalentContact SG-SG 2.01Å; C52-C92 PolarHBondContact SG-SG 2.86Å
53	K	91.6	Very high	94.1	Very high	167 Å²	167	58.6 Å²	58.6	73%	0.726	29%	0.293	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.5	5.3	174.8	-66.5	173.2	-176.8	179.1	0	112.9	Q49 R50 Y51 K55	Q49-K53 WeakPolarHBondContact O-CG 3.42Å; Q49-K53 PolarHBondContact O-N 3.36Å; R50-K53 CarbonylContact O-C 3.58Å; R50-K53 WeakPolarHBondContact O-CA 3.28Å; R50-K53 WeakPolarHBondContact O-CB 3.26Å; R50-K53 PolarHBondContact O-N 3.47Å; Y51-K53 PolarHBondContact O-N 3.35Å; K53-K55 VanDerWaalsContact C-N 3.31Å; K53-K55 HydrophobicContact CB-CD 4.41Å
54	G	91.6	Very high	93.9	Very high	48 Å²	48	57 Å²	57	50%	0.495	29%	0.288	S	S	.	.	T	Hydrogen-bonded Turn	trans	81.6	5.9	-177.1	0	0	0	0	0	114.3	R50 Y51 C52 F56	R50-G54 PolarHBondContact O-N 3.32Å; Y51-G54 PolarHBondContact O-N 3.1Å; C52-G54 VanDerWaalsContact C-N 3.28Å; G54-F56 VanDerWaalsContact C-N 3.32Å; G54-F56 WeakPolarHBondContact O-CD2 3.42Å; G54-F56 PolarHBondContact O-N 3.34Å; G54-F56 VanDerWaalsContact O-N 3.08Å
55	K	94.4	Very high	93.7	Very high	98 Å²	98	56.7 Å²	56.7	43%	0.426	29%	0.288	S	S	.	.			trans	-86.6	69.9	-179.1	-66.4	168.5	156	-126.2	0	110.7	R50 Y51 K53 N57 E58	R50-K55 HydrophobicContact CB-CB 4.28Å; R50-K55 WeakPolarHBondContact O-CB 3.46Å; R50-K55 PolarHBondContact O-N 3.05Å; Y51-K55 WeakPolarHBondContact CD1-O 3.42Å; K53-K55 VanDerWaalsContact C-N 3.31Å; K53-K55 HydrophobicContact CB-CD 4.41Å; K55-N57 VanDerWaalsContact C-N 3.27Å; K55-N57 PolarHBondContact O-N 3.01Å; K55-E58 HydrophobicContact CB-CG 4.36Å; K55-E58 VanDerWaalsContact CD-OE1 3.31Å; K55-E58 WeakPolarHBondContact CD-OE1 3.48Å; K55-E58 WeakPolarHBondContact CE-OE1 3.43Å; K55-E58 IonicContact NZ-OE1 2.8Å; K55-E58 PolarHBondContact NZ-OE1 3.49Å; K55-E58 IonicContact NZ-OE2 3.74Å
56	F	94.2	Very high	93.7	Very high	98 Å²	98	57.5 Å²	57.5	43%	0.43	29%	0.292	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76	-13.1	-179.5	-65.8	-80.1	0	0	0	114.1	Y51 G54 L71	Y51-F56 HydrophobicContact CD1-CD1 4.09Å; Y51-F56 AromaticContact CD2-CD1 3.67Å; Y51-F56 HydrophobicContact CD2-CD1 3.67Å; Y51-F56 AromaticContact CD2-CE1 3.84Å; Y51-F56 HydrophobicContact CD2-CE1 3.84Å; Y51-F56 HydrophobicContact CE1-CD1 4.39Å; Y51-F56 HydrophobicContact CE2-CD1 4.01Å; Y51-F56 AromaticContact CG-CD1 3.71Å; Y51-F56 HydrophobicContact CG-CD1 3.71Å; Y51-F56 AromaticContact CG-CE1 3.91Å; Y51-F56 HydrophobicContact CG-CE1 3.91Å; G54-F56 VanDerWaalsContact C-N 3.32Å; G54-F56 WeakPolarHBondContact O-CD2 3.42Å; G54-F56 PolarHBondContact O-N 3.34Å; G54-F56 VanDerWaalsContact O-N 3.08Å; F56-L71 HydrophobicContact CD1-CD2 4.26Å; F56-L71 HydrophobicContact CE1-CD2 4.14Å
57	N	94.1	Very high	93.7	Very high	168 Å²	168	57 Å²	57	90%	0.898	29%	0.288	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.2	-5.1	-178.8	-60.1	-21.4	0	0	0	113.4	K55	K55-N57 VanDerWaalsContact C-N 3.27Å; K55-N57 PolarHBondContact O-N 3.01Å
58	E	94.1	Very high	93.7	Very high	72 Å²	72	57.1 Å²	57.1	34%	0.336	29%	0.29	S	S	.	.			trans	-95.2	134.4	177.4	-67.8	177.9	-159.7	0	0	109.7	Q47 R50 K55	Q47-E58 PolarHBondContact NE2-O 3.13Å; R50-E58 WeakPolarHBondContact CD-OE2 3.48Å; R50-E58 IonicContact NE-OE2 2.64Å; K55-E58 HydrophobicContact CB-CG 4.36Å; K55-E58 VanDerWaalsContact CD-OE1 3.31Å; K55-E58 WeakPolarHBondContact CD-OE1 3.48Å; K55-E58 WeakPolarHBondContact CE-OE1 3.43Å; K55-E58 IonicContact NZ-OE1 2.8Å; K55-E58 PolarHBondContact NZ-OE1 3.49Å; K55-E58 IonicContact NZ-OE2 3.74Å
59	W	94.4	Very high	93.8	Very high	75 Å²	75	57.1 Å²	57.1	28%	0.284	29%	0.29	S	S	.	.			trans	-137.4	134	179.2	-169.7	-98.6	0	0	0	111.6	Q47 Y51 I63 T65 P67 Y70	Q47-W59 HydrophobicContact CG-CE3 4.43Å; Q47-W59 HydrophobicContact CG-CZ3 4.38Å; Y51-W59 WeakPolarHBondContact OH-CZ3 3.38Å; W59-I63 HydrophobicContact CH2-CG2 4.1Å; W59-I63 HydrophobicContact CZ2-CB 3.91Å; W59-I63 HydrophobicContact CZ2-CG2 3.51Å; W59-T65 VanDerWaalsContact CZ2-O 3.22Å; W59-T65 WeakPolarHBondContact CZ2-O 3.49Å; W59-P67 HydrophobicContact CH2-CB 3.99Å; W59-P67 HydrophobicContact CZ3-CB 3.72Å; W59-Y70 HydrophobicContact CH2-CD2 4.14Å; W59-Y70 AromaticContact CH2-CE2 3.58Å; W59-Y70 HydrophobicContact CH2-CE2 3.58Å; W59-Y70 AromaticContact CZ3-CD2 3.89Å; W59-Y70 HydrophobicContact CZ3-CD2 3.89Å; W59-Y70 AromaticContact CZ3-CE2 3.67Å; W59-Y70 HydrophobicContact CZ3-CE2 3.67Å
60	D	93.8	Very high	93.9	Very high	30 Å²	30	53.9 Å²	53.9	16%	0.16	28%	0.275	C	S	.	.			trans	-79.4	121.8	174.3	-165.8	-51.5	0	0	0	110.6	Q47 M62 I63	Q47-D60 VanDerWaalsContact OE1-N 3.1Å; D60-M62 PolarHBondContact O-N 3.02Å; D60-M62 VanDerWaalsContact O-N 3.16Å; D60-M62 WeakPolarHBondContact OD1-CB 3.31Å; D60-M62 PolarHBondContact OD1-N 3.04Å; D60-I63 HydrophobicContact CB-CD1 3.56Å; D60-I63 HydrophobicContact CB-CG1 3.99Å; D60-I63 PolarHBondContact O-N 2.69Å; D60-I63 VanDerWaalsContact O-N 3.11Å
61	P	91.5	Very high	94	Very high	85 Å²	85	53.9 Å²	53.9	55%	0.552	28%	0.28	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.8	-14.3	-174.6	28.6	-36.3	0	0	0	114.1	I63 G281 D282	P61-I63 VanDerWaalsContact C-N 3.31Å; P61-G281 VanDerWaalsContact O-CA 3.25Å; P61-G281 WeakPolarHBondContact O-CA 3.29Å; P61-D282 PolarHBondContact O-N 3.18Å
62	M	90.5	Very high	94.1	Very high	95 Å²	95	54.9 Å²	54.9	47%	0.468	29%	0.288	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.1	-12.5	176.1	-62.8	-63.6	98.8	0	0	112.7	F43 D60 T64	F43-M62 HydrophobicContact CD1-CB 3.66Å; F43-M62 HydrophobicContact CD1-CG 4.18Å; F43-M62 HydrophobicContact CE1-CB 3.64Å; F43-M62 HydrophobicContact CE1-CG 3.74Å; F43-M62 HydrophobicContact CG-CB 4.13Å; F43-M62 HydrophobicContact CZ-CB 4.08Å; F43-M62 HydrophobicContact CZ-CG 4.26Å; D60-M62 PolarHBondContact O-N 3.02Å; D60-M62 VanDerWaalsContact O-N 3.16Å; D60-M62 WeakPolarHBondContact OD1-CB 3.31Å; D60-M62 PolarHBondContact OD1-N 3.04Å; M62-T64 PolarHBondContact O-N 3.03Å
63	I	92.8	Very high	94.2	Very high	3 Å²	3	54.5 Å²	54.5	2%	0.015	29%	0.285	C	S	.	.			trans	-80.3	117.2	178.6	-60.7	162.8	0	0	0	109.8	F43 Q47 W59 D60 P61 T65 Y70 G281	F43-I63 HydrophobicContact CB-CG1 3.94Å; Q47-I63 HydrophobicContact CB-CD1 3.59Å; Q47-I63 HydrophobicContact CG-CD1 3.55Å; W59-I63 HydrophobicContact CH2-CG2 4.1Å; W59-I63 HydrophobicContact CZ2-CB 3.91Å; W59-I63 HydrophobicContact CZ2-CG2 3.51Å; D60-I63 HydrophobicContact CB-CD1 3.56Å; D60-I63 HydrophobicContact CB-CG1 3.99Å; D60-I63 PolarHBondContact O-N 2.69Å; D60-I63 VanDerWaalsContact O-N 3.11Å; P61-I63 VanDerWaalsContact C-N 3.31Å; I63-T65 WeakPolarHBondContact CG2-OG1 3.44Å; I63-Y70 HydrophobicContact CD1-CE2 4.3Å; I63-Y70 WeakPolarHBondContact CD1-OH 3.37Å; I63-Y70 WeakPolarHBondContact CG2-OH 3.3Å; I63-G281 VanDerWaalsContact O-CA 3.32Å; I63-G281 WeakPolarHBondContact O-CA 2.98Å; I63-G281 PolarHBondContact O-N 3.23Å; I63-G281 VanDerWaalsContact O-N 3.15Å
64	T	91.2	Very high	94.3	Very high	32 Å²	32	47.2 Å²	47.2	20%	0.196	25%	0.254	C	S	.	.			trans	-86.8	-21.8	-178.9	59.4	0	0	0	0	113.2	M62 Q188 V280 G281 D282 H286	M62-T64 PolarHBondContact O-N 3.03Å; T64-Q188 PolarHBondContact O-NE2 2.8Å; T64-V280 PolarHBondContact O-N 3.41Å; T64-V280 VanDerWaalsContact O-N 3.11Å; T64-G281 WeakPolarHBondContact CG2-O 3.47Å; T64-D282 HydrophobicContact CG2-CB 3.89Å; T64-H286 WeakPolarHBondContact CG2-CE1 3.22Å
65	T	93.4	Very high	94.4	Very high	11 Å²	11	47.1 Å²	47.1	7%	0.067	25%	0.254	C	S	.	.	S	Bend	trans	-85.4	168.5	-176.5	58.5	0	0	0	0	113.3	W59 I63 T153	W59-T65 VanDerWaalsContact CZ2-O 3.22Å; W59-T65 WeakPolarHBondContact CZ2-O 3.49Å; I63-T65 WeakPolarHBondContact CG2-OG1 3.44Å; T65-T153 HydrophobicContact CG2-CG2 4.16Å
66	L	95.3	Very high	94.3	Very high	19 Å²	19	45.2 Å²	45.2	10%	0.099	25%	0.248	C	C	.	.			trans	-80.2	166.3	171.9	-78.1	171	0	0	0	111.9	G68 V184 L185 Q188 F271 V280	L66-G68 PolarHBondContact O-N 3.29Å; L66-G68 VanDerWaalsContact O-N 3.09Å; L66-V184 HydrophobicContact CD1-CG1 4.09Å; L66-V184 WeakPolarHBondContact CD1-O 3.37Å; L66-L185 CarbonylContact C-O 3.59Å; L66-L185 WeakPolarHBondContact CA-O 3.11Å; L66-L185 HydrophobicContact CB-CD2 4.47Å; L66-L185 WeakPolarHBondContact CB-O 3.16Å; L66-L185 HydrophobicContact CD1-CD2 4.43Å; L66-L185 VanDerWaalsContact O-O 3.11Å; L66-Q188 HydrophobicContact CD1-CG 3.84Å; L66-Q188 HydrophobicContact CG-CG 4.04Å; L66-F271 HydrophobicContact CD2-CE2 4.06Å; L66-F271 HydrophobicContact CD2-CZ 4.03Å; L66-V280 HydrophobicContact CD2-CG2 3.74Å; L66-V280 HydrophobicContact CG-CG2 4.29Å
67	P	96.5	Very high	94.1	Very high	28 Å²	28	41.1 Å²	41.1	18%	0.182	23%	0.23	C	C	.	.	T	Hydrogen-bonded Turn	trans	-74.5	5.5	-170.4	29.1	-37.8	0	0	0	115.7	Y51 W59 L69 Y70 L71	Y51-P67 HydrophobicContact CE2-CB 4.06Å; W59-P67 HydrophobicContact CH2-CB 3.99Å; W59-P67 HydrophobicContact CZ3-CB 3.72Å; P67-L69 VanDerWaalsContact C-N 3.33Å; P67-L69 PolarHBondContact O-N 3.27Å; P67-Y70 HydrophobicContact CB-CD2 4.31Å; P67-Y70 PolarHBondContact O-N 3Å; P67-Y70 VanDerWaalsContact O-N 3.08Å; P67-L71 HydrophobicContact CB-CD1 4.12Å; P67-L71 HydrophobicContact CB-CG 4.2Å; P67-L71 HydrophobicContact CG-CD1 4.03Å; P67-L71 WeakPolarHBondContact O-CG 3.32Å; P67-L71 PolarHBondContact O-N 3.41Å
68	G	97.1	Very high	93.9	Very high	3 Å²	3	37.5 Å²	37.5	3%	0.031	21%	0.207	C	C	.	.	H	α-helix	trans	-57.7	-40.4	-169.5	0	0	0	0	0	114.1	L66 Y70 L71 V72 L185 F186	L66-G68 PolarHBondContact O-N 3.29Å; L66-G68 VanDerWaalsContact O-N 3.09Å; G68-Y70 VanDerWaalsContact C-N 3.33Å; G68-Y70 PolarHBondContact O-N 2.9Å; G68-L71 PolarHBondContact O-N 3.38Å; G68-V72 WeakPolarHBondContact O-CG2 3.15Å; G68-V72 PolarHBondContact O-N 3.3Å; G68-L185 VanDerWaalsContact CA-O 3.27Å; G68-L185 WeakPolarHBondContact CA-O 3.31Å; G68-L185 PolarHBondContact N-O 2.96Å; G68-F186 WeakPolarHBondContact O-CE2 3.48Å
69	L	97.1	Very high	93.6	Very high	0 Å²	0	37.3 Å²	37.3	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-57.4	-47.2	176.2	177	63	0	0	0	111.3	P67 S73 Y151 T153 F186	P67-L69 VanDerWaalsContact C-N 3.33Å; P67-L69 PolarHBondContact O-N 3.27Å; L69-S73 WeakPolarHBondContact O-CB 2.99Å; L69-S73 PolarHBondContact O-N 2.92Å; L69-S73 PolarHBondContact O-OG 2.9Å; L69-Y151 HydrophobicContact CD1-CD2 4.27Å; L69-Y151 HydrophobicContact CD1-CE2 3.69Å; L69-Y151 HydrophobicContact CD2-CD1 4.1Å; L69-Y151 HydrophobicContact CD2-CD2 4.45Å; L69-Y151 HydrophobicContact CD2-CE1 3.82Å; L69-Y151 HydrophobicContact CD2-CE2 4.19Å; L69-Y151 HydrophobicContact CD2-CG 4.42Å; L69-Y151 HydrophobicContact CG-CE1 4.05Å; L69-Y151 HydrophobicContact CG-CE2 3.9Å; L69-Y151 PolarHBondContact O-OH 3.11Å; L69-T153 HydrophobicContact CB-CG2 4.09Å; L69-T153 HydrophobicContact CD2-CG2 3.97Å; L69-F186 HydrophobicContact CB-CD1 4.24Å; L69-F186 HydrophobicContact CB-CE1 3.98Å; L69-F186 HydrophobicContact CD1-CE1 3.86Å
70	Y	96.7	Very high	93.3	Very high	0 Å²	0	38.1 Å²	38.1	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-72.1	-44	-176.6	-41.6	-46.9	0	0	0	111.8	H44 Q47 A48 Y51 W59 I63 P67 G68 V72 S73 V74 Y151	H44-Y70 HydrophobicContact CB-CE1 3.92Å; H44-Y70 AromaticContact ND1-CE1 3.79Å; H44-Y70 AromaticContact ND1-CZ 3.57Å; H44-Y70 PolarHBondContact ND1-OH 2.92Å; H44-Y70 WeakPolarHBondContact O-CE1 3.43Å; Q47-Y70 HydrophobicContact CB-CE1 4.31Å; Q47-Y70 HydrophobicContact CB-CE2 4.23Å; Q47-Y70 HydrophobicContact CG-CD2 3.82Å; Q47-Y70 HydrophobicContact CG-CE1 4.38Å; Q47-Y70 HydrophobicContact CG-CE2 3.48Å; Q47-Y70 VanDerWaalsContact CG-CE2 3.48Å; Q47-Y70 HydrophobicContact CG-CG 4.39Å; A48-Y70 HydrophobicContact CB-CD1 3.82Å; A48-Y70 HydrophobicContact CB-CG 4.49Å; Y51-Y70 HydrophobicContact CD2-CG 4.5Å; Y51-Y70 HydrophobicContact CE2-CD2 4.23Å; W59-Y70 HydrophobicContact CH2-CD2 4.14Å; W59-Y70 AromaticContact CH2-CE2 3.58Å; W59-Y70 HydrophobicContact CH2-CE2 3.58Å; W59-Y70 AromaticContact CZ3-CD2 3.89Å; W59-Y70 HydrophobicContact CZ3-CD2 3.89Å; W59-Y70 AromaticContact CZ3-CE2 3.67Å; W59-Y70 HydrophobicContact CZ3-CE2 3.67Å; I63-Y70 HydrophobicContact CD1-CE2 4.3Å; I63-Y70 WeakPolarHBondContact CD1-OH 3.37Å; I63-Y70 WeakPolarHBondContact CG2-OH 3.3Å; P67-Y70 HydrophobicContact CB-CD2 4.31Å; P67-Y70 PolarHBondContact O-N 3Å; P67-Y70 VanDerWaalsContact O-N 3.08Å; G68-Y70 VanDerWaalsContact C-N 3.33Å; G68-Y70 PolarHBondContact O-N 2.9Å; Y70-V72 VanDerWaalsContact C-N 3.32Å; Y70-V72 PolarHBondContact O-N 3.17Å; Y70-S73 PolarHBondContact O-N 3.33Å; Y70-V74 WeakPolarHBondContact O-CB 3.44Å; Y70-V74 VanDerWaalsContact O-CG2 3.26Å; Y70-V74 WeakPolarHBondContact O-CG2 3.34Å; Y70-V74 PolarHBondContact O-N 3.38Å; Y70-Y151 HydrophobicContact CD1-CE1 4.1Å; Y70-Y151 HydrophobicContact CE1-CE1 4.15Å
71	L	96.9	Very high	92.9	Very high	75 Å²	75	37 Å²	37	39%	0.393	22%	0.215	S	C	.	.	H	α-helix	trans	-59.6	-45.2	179.6	-67.9	174.4	0	0	0	111	Y51 F56 P67 G68 G75	Y51-L71 HydrophobicContact CD2-CD2 4.18Å; Y51-L71 HydrophobicContact CE2-CD2 4.03Å; Y51-L71 HydrophobicContact CE2-CG 4.39Å; F56-L71 HydrophobicContact CD1-CD2 4.26Å; F56-L71 HydrophobicContact CE1-CD2 4.14Å; P67-L71 HydrophobicContact CB-CD1 4.12Å; P67-L71 HydrophobicContact CB-CG 4.2Å; P67-L71 HydrophobicContact CG-CD1 4.03Å; P67-L71 WeakPolarHBondContact O-CG 3.32Å; P67-L71 PolarHBondContact O-N 3.41Å; G68-L71 PolarHBondContact O-N 3.38Å; L71-G75 PolarHBondContact O-N 2.93Å
72	V	96.4	Very high	92.6	Very high	38 Å²	38	42.6 Å²	42.6	23%	0.23	23%	0.225	C	C	.	.	H	α-helix	trans	-70.4	-43.2	178.3	178.1	0	0	0	0	111.4	G68 Y70 V74 G75 I76 F104 F160 F186	G68-V72 WeakPolarHBondContact O-CG2 3.15Å; G68-V72 PolarHBondContact O-N 3.3Å; Y70-V72 VanDerWaalsContact C-N 3.32Å; Y70-V72 PolarHBondContact O-N 3.17Å; V72-V74 PolarHBondContact O-N 2.77Å; V72-G75 PolarHBondContact O-N 3.36Å; V72-I76 HydrophobicContact CG1-CD1 3.63Å; V72-I76 HydrophobicContact CG1-CG1 4.27Å; V72-I76 WeakPolarHBondContact O-CG1 3.48Å; V72-I76 PolarHBondContact O-N 2.91Å; V72-F104 HydrophobicContact CB-CZ 4.38Å; V72-F104 HydrophobicContact CG1-CE1 4.44Å; V72-F104 HydrophobicContact CG1-CE2 4.4Å; V72-F104 HydrophobicContact CG1-CZ 3.64Å; V72-F160 HydrophobicContact CG2-CE2 4.3Å; V72-F160 HydrophobicContact CG2-CZ 4.32Å; V72-F186 HydrophobicContact CB-CE2 4.38Å; V72-F186 HydrophobicContact CB-CZ 4.12Å; V72-F186 HydrophobicContact CG2-CE2 3.82Å; V72-F186 HydrophobicContact CG2-CZ 4.07Å
73	S	95.3	Very high	92.4	Very high	0 Å²	0	44.2 Å²	44.2	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-60.1	-48	177.8	-63.3	0	0	0	0	111.8	L69 Y70 G75 I76 I77 T100 Y151	L69-S73 WeakPolarHBondContact O-CB 2.99Å; L69-S73 PolarHBondContact O-N 2.92Å; L69-S73 PolarHBondContact O-OG 2.9Å; Y70-S73 PolarHBondContact O-N 3.33Å; S73-G75 PolarHBondContact O-N 2.89Å; S73-I76 PolarHBondContact O-N 2.86Å; S73-I77 WeakPolarHBondContact O-CB 3.48Å; S73-I77 WeakPolarHBondContact O-CG1 3.26Å; S73-I77 PolarHBondContact O-N 3.46Å; S73-T100 PolarHBondContact OG-OG1 3.43Å; S73-Y151 WeakPolarHBondContact CB-OH 3.21Å; S73-Y151 VanDerWaalsContact OG-CE2 3.24Å; S73-Y151 WeakPolarHBondContact OG-CE2 3.27Å; S73-Y151 PolarHBondContact OG-OH 3.22Å
74	V	93.4	Very high	92.1	Very high	13 Å²	13	46.9 Å²	46.9	8%	0.079	26%	0.257	C	S	.	.	H	α-helix	trans	-63.8	-42.4	177.3	177.6	0	0	0	0	111	Y70 V72 I76 I77 K78	Y70-V74 WeakPolarHBondContact O-CB 3.44Å; Y70-V74 VanDerWaalsContact O-CG2 3.26Å; Y70-V74 WeakPolarHBondContact O-CG2 3.34Å; Y70-V74 PolarHBondContact O-N 3.38Å; V72-V74 PolarHBondContact O-N 2.77Å; V74-I76 VanDerWaalsContact C-N 3.26Å; V74-I76 PolarHBondContact O-N 3.36Å; V74-I77 PolarHBondContact O-N 3.5Å; V74-K78 HydrophobicContact CG1-CG 3.77Å; V74-K78 VanDerWaalsContact O-CB 3.31Å; V74-K78 WeakPolarHBondContact O-CB 3.3Å; V74-K78 PolarHBondContact O-N 3.46Å
75	G	93.1	Very high	91.7	Very high	47 Å²	47	54.5 Å²	54.5	49%	0.485	29%	0.288	S	S	.	.	H	α-helix	trans	-61.8	-28.5	178.1	0	0	0	0	0	114.2	L71 V72 S73 P79	L71-G75 PolarHBondContact O-N 2.93Å; V72-G75 PolarHBondContact O-N 3.36Å; S73-G75 PolarHBondContact O-N 2.89Å; G75-P79 WeakPolarHBondContact O-CD 3.35Å; G75-P79 VanDerWaalsContact O-CG 3.22Å; G75-P79 WeakPolarHBondContact O-CG 3.28Å
76	I	92.3	Very high	91	Very high	58 Å²	58	58.2 Å²	58.2	30%	0.297	31%	0.306	S	S	.	.	H	α-helix	trans	-86.9	-49	174.4	-66	169.6	0	0	0	110.9	V72 S73 V74 M80 L103	V72-I76 HydrophobicContact CG1-CD1 3.63Å; V72-I76 HydrophobicContact CG1-CG1 4.27Å; V72-I76 WeakPolarHBondContact O-CG1 3.48Å; V72-I76 PolarHBondContact O-N 2.91Å; S73-I76 PolarHBondContact O-N 2.86Å; V74-I76 VanDerWaalsContact C-N 3.26Å; V74-I76 PolarHBondContact O-N 3.36Å; I76-M80 HydrophobicContact CG2-CE 4.19Å; I76-M80 WeakPolarHBondContact O-CB 3.25Å; I76-M80 PolarHBondContact O-N 3.49Å; I76-L103 HydrophobicContact CG2-CD1 4.19Å
77	I	91.1	Very high	89.7	Confident	12 Å²	12	62.3 Å²	62.3	6%	0.062	33%	0.332	C	S	.	.	H	α-helix	trans	-68.9	-43.3	-170.5	-72.8	172.4	0	0	0	111.6	S73 V74 M80 A81 A91 M96 L97 T100	S73-I77 WeakPolarHBondContact O-CB 3.48Å; S73-I77 WeakPolarHBondContact O-CG1 3.26Å; S73-I77 PolarHBondContact O-N 3.46Å; V74-I77 PolarHBondContact O-N 3.5Å; I77-M80 PolarHBondContact O-N 3.41Å; I77-A81 WeakPolarHBondContact O-CB 3.3Å; I77-A81 PolarHBondContact O-N 2.95Å; I77-A91 HydrophobicContact CG2-CB 4.24Å; I77-A91 WeakPolarHBondContact CG2-O 3.15Å; I77-M96 HydrophobicContact CD1-CB 4.19Å; I77-L97 HydrophobicContact CD1-CD2 3.79Å; I77-L97 HydrophobicContact CD1-CG 4.45Å; I77-T100 HydrophobicContact CD1-CG2 3.88Å; I77-T100 HydrophobicContact CG1-CG2 4.06Å
78	K	88.1	Confident	87.9	Confident	92 Å²	92	64 Å²	64	40%	0.4	36%	0.355	S	S	.	.	H	α-helix	trans	-64.6	-50	-175.1	-80	-76.5	-171.1	168.5	0	112.7	C52 V74 M80 A81 W82	C52-K78 WeakPolarHBondContact O-CE 3.37Å; C52-K78 PolarHBondContact O-NZ 3.26Å; V74-K78 HydrophobicContact CG1-CG 3.77Å; V74-K78 VanDerWaalsContact O-CB 3.31Å; V74-K78 WeakPolarHBondContact O-CB 3.3Å; V74-K78 PolarHBondContact O-N 3.46Å; K78-M80 VanDerWaalsContact C-N 3.32Å; K78-M80 PolarHBondContact O-N 3.3Å; K78-A81 PolarHBondContact O-N 3.48Å; K78-W82 WeakPolarHBondContact O-CB 3.36Å; K78-W82 PolarHBondContact O-N 3.45Å
79	P	89	Confident	86.2	Confident	67 Å²	67	68.8 Å²	68.8	44%	0.435	39%	0.388	S	S	.	.	H	α-helix	trans	-60.7	-41.6	174.9	-25.2	36.4	0	0	0	112.3	G75 W82 L83	G75-P79 WeakPolarHBondContact O-CD 3.35Å; G75-P79 VanDerWaalsContact O-CG 3.22Å; G75-P79 WeakPolarHBondContact O-CG 3.28Å; P79-W82 PolarHBondContact O-N 3.14Å; P79-L83 WeakPolarHBondContact O-CG 3.29Å; P79-L83 PolarHBondContact O-N 2.84Å
80	M	87.1	Confident	84.9	Confident	93 Å²	93	72.3 Å²	72.3	46%	0.458	41%	0.409	S	S	.	.	H	α-helix	trans	-63.7	-45	178.5	-175.9	-174.7	-64.8	0	0	112.2	I76 I77 K78 W82 L83 A84	I76-M80 HydrophobicContact CG2-CE 4.19Å; I76-M80 WeakPolarHBondContact O-CB 3.25Å; I76-M80 PolarHBondContact O-N 3.49Å; I77-M80 PolarHBondContact O-N 3.41Å; K78-M80 VanDerWaalsContact C-N 3.32Å; K78-M80 PolarHBondContact O-N 3.3Å; M80-W82 VanDerWaalsContact C-N 3.32Å; M80-W82 PolarHBondContact O-N 3.4Å; M80-L83 PolarHBondContact O-N 3.41Å; M80-A84 VanDerWaalsContact O-CB 3.29Å; M80-A84 WeakPolarHBondContact O-CB 3.31Å; M80-A84 PolarHBondContact O-N 3.26Å
81	A	86.7	Confident	83.9	Confident	7 Å²	7	72.6 Å²	72.6	6%	0.058	41%	0.411	C	S	.	.	H	α-helix	trans	-64.2	-38.7	177.8	0	0	0	0	0	111.7	I77 K78 A84 K85 L86 A91	I77-A81 WeakPolarHBondContact O-CB 3.3Å; I77-A81 PolarHBondContact O-N 2.95Å; K78-A81 PolarHBondContact O-N 3.48Å; A81-A84 CarbonylContact O-C 3.06Å; A81-A84 PolarHBondContact O-N 3.05Å; A81-K85 PolarHBondContact O-N 2.9Å; A81-L86 HydrophobicContact CB-CB 4.14Å; A81-L86 PolarHBondContact O-N 3.14Å; A81-A91 HydrophobicContact CB-CB 3.6Å
82	W	85.3	Confident	83.5	Confident	201 Å²	201	69.4 Å²	69.4	76%	0.761	40%	0.396	S	S	*	.	H	α-helix	trans	-62.2	-48	173.5	177.8	80.7	0	0	0	111.7	K78 P79 M80 A84 K85	K78-W82 WeakPolarHBondContact O-CB 3.36Å; K78-W82 PolarHBondContact O-N 3.45Å; P79-W82 PolarHBondContact O-N 3.14Å; M80-W82 VanDerWaalsContact C-N 3.32Å; M80-W82 PolarHBondContact O-N 3.4Å; W82-A84 VanDerWaalsContact C-N 3.33Å; W82-A84 PolarHBondContact O-N 2.69Å; W82-K85 PolarHBondContact O-N 3.26Å
83	L	86.8	Confident	83.3	Confident	129 Å²	129	69.3 Å²	69.3	68%	0.675	40%	0.397	S	S	*	.	H	α-helix	trans	-61.1	-39.9	176.3	-72.9	170.9	0	0	0	112.6	P79 M80 K85	P79-L83 WeakPolarHBondContact O-CG 3.29Å; P79-L83 PolarHBondContact O-N 2.84Å; M80-L83 PolarHBondContact O-N 3.41Å; L83-K85 VanDerWaalsContact C-N 3.3Å; L83-K85 PolarHBondContact O-N 3.15Å
84	A	85.1	Confident	83.3	Confident	59 Å²	59	70.3 Å²	70.3	49%	0.488	40%	0.403	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85	3.3	-179	0	0	0	0	0	114	M80 A81 W82 L86	M80-A84 VanDerWaalsContact O-CB 3.29Å; M80-A84 WeakPolarHBondContact O-CB 3.31Å; M80-A84 PolarHBondContact O-N 3.26Å; A81-A84 CarbonylContact O-C 3.06Å; A81-A84 PolarHBondContact O-N 3.05Å; W82-A84 VanDerWaalsContact C-N 3.33Å; W82-A84 PolarHBondContact O-N 2.69Å; A84-L86 HydrophobicContact CB-CD1 3.95Å; A84-L86 HydrophobicContact CB-CG 3.91Å; A84-L86 PolarHBondContact O-N 3.47Å
85	K	84.1	Confident	83.3	Confident	193 Å²	193	71 Å²	71	84%	0.839	41%	0.41	S	S	*	.	T	Hydrogen-bonded Turn	trans	52.8	32.8	-175.4	-57.7	-178.5	179.9	179.4	0	113.6	A81 W82 L83	A81-K85 PolarHBondContact O-N 2.9Å; W82-K85 PolarHBondContact O-N 3.26Å; L83-K85 VanDerWaalsContact C-N 3.3Å; L83-K85 PolarHBondContact O-N 3.15Å
86	L	78	Confident	83.4	Confident	88 Å²	88	72.1 Å²	72.1	46%	0.461	40%	0.403	S	S	.	.			trans	-81.2	132	176.5	-67	170.7	0	0	0	110.1	A81 A84	A81-L86 HydrophobicContact CB-CB 4.14Å; A81-L86 PolarHBondContact O-N 3.14Å; A84-L86 HydrophobicContact CB-CD1 3.95Å; A84-L86 HydrophobicContact CB-CG 3.91Å; A84-L86 PolarHBondContact O-N 3.47Å
87	T	66.8	Low	83.5	Confident	105 Å²	105	69.4 Å²	69.4	64%	0.644	39%	0.389	S	S	*	.			trans	-85.6	161.2	-177.2	53.9	0	0	0	0	113.5	S89 V90	T87-S89 PolarHBondContact O-N 3.09Å; T87-S89 VanDerWaalsContact O-N 3.1Å; T87-V90 PolarHBondContact O-N 2.54Å; T87-V90 VanDerWaalsContact O-N 3.16Å
88	G	59.8	Low	83.8	Confident	63 Å²	63	68.9 Å²	68.9	65%	0.649	39%	0.386	S	S	*	.	H	α-helix	trans	-55.2	-30.7	-153.6	0	0	0	0	0	119.3
89	S	61.9	Low	84.2	Confident	104 Å²	104	67 Å²	67	73%	0.727	38%	0.378	S	S	*	.	H	α-helix	trans	-83.4	-27.4	-178.9	58	0	0	0	0	113.5	T87	T87-S89 PolarHBondContact O-N 3.09Å; T87-S89 VanDerWaalsContact O-N 3.1Å
90	V	70.3	Confident	84.6	Confident	74 Å²	74	63.9 Å²	63.9	45%	0.448	36%	0.358	S	S	.	.	H	α-helix	trans	-79	-37.1	-178.4	-178.4	0	0	0	0	110.9	T87 C92 S93	T87-V90 PolarHBondContact O-N 2.54Å; T87-V90 VanDerWaalsContact O-N 3.16Å; V90-C92 VanDerWaalsContact C-N 3.29Å; V90-C92 PolarHBondContact O-N 3.02Å; V90-S93 PolarHBondContact O-N 2.74Å; V90-S93 PolarHBondContact O-OG 3.34Å; V90-S93 VanDerWaalsContact O-OG 3.09Å
91	A	75.3	Confident	85.1	Confident	6 Å²	6	59.5 Å²	59.5	5%	0.05	34%	0.337	C	S	.	.	H	α-helix	trans	-53.6	-43.7	-177	0	0	0	0	0	112.2	I77 A81 M96	I77-A91 HydrophobicContact CG2-CB 4.24Å; I77-A91 WeakPolarHBondContact CG2-O 3.15Å; A81-A91 HydrophobicContact CB-CB 3.6Å; A91-M96 WeakPolarHBondContact O-CB 3.5Å; A91-M96 WeakPolarHBondContact O-CG 3.23Å
92	C	87.8	Confident	85.6	Confident	9 Å²	9	59.1 Å²	59.1	6%	0.061	33%	0.334	C	S	.	.	T	Hydrogen-bonded Turn	trans	-113	35.4	-178.8	-59.9	0	0	0	0	113.8	Q49 C52 V90	Q49-C92 HydrophobicContact CG-CB 4.43Å; Q49-C92 WeakPolarHBondContact CG-O 3.33Å; Q49-C92 PolarHBondContact NE2-O 3.01Å; C52-C92 HydrophobicContact CB-CB 3.67Å; C52-C92 WeakPolarHBondContact CB-SG 3.13Å; C52-C92 WeakPolarHBondContact SG-CB 3.21Å; C52-C92 CovalentContact SG-SG 2.01Å; C52-C92 PolarHBondContact SG-SG 2.86Å; V90-C92 VanDerWaalsContact C-N 3.29Å; V90-C92 PolarHBondContact O-N 3.02Å
93	S	92.4	Very high	86.2	Confident	36 Å²	36	52.3 Å²	52.3	25%	0.252	31%	0.312	S	S	.	.			trans	-62.6	156.2	167.5	62.5	0	0	0	0	111.2	V90 A95 M96 L97	V90-S93 PolarHBondContact O-N 2.74Å; V90-S93 PolarHBondContact O-OG 3.34Å; V90-S93 VanDerWaalsContact O-OG 3.09Å; S93-A95 PolarHBondContact O-N 3.32Å; S93-A95 VanDerWaalsContact O-N 3.16Å; S93-M96 PolarHBondContact O-N 2.92Å; S93-M96 WeakPolarHBondContact OG-CG 3.5Å; S93-M96 PolarHBondContact OG-N 2.94Å; S93-L97 PolarHBondContact O-N 3.37Å
94	T	94.9	Very high	86.7	Confident	21 Å²	21	46.8 Å²	46.8	13%	0.129	28%	0.282	C	S	.	.	H	α-helix	trans	-50.7	-40.2	174.9	-49.1	0	0	0	0	111.9	V45 L97 R98	V45-T94 HydrophobicContact CG2-CG2 4.1Å; T94-L97 PolarHBondContact O-N 3.45Å; T94-R98 HydrophobicContact CG2-CG 4.44Å; T94-R98 WeakPolarHBondContact O-CB 3.4Å; T94-R98 VanDerWaalsContact O-CG 3.3Å; T94-R98 WeakPolarHBondContact O-CG 3.46Å; T94-R98 PolarHBondContact O-N 2.66Å
95	A	94.7	Very high	87.3	Confident	28 Å²	28	44 Å²	44	23%	0.231	26%	0.259	C	S	.	.	H	α-helix	trans	-62.9	-46.6	177.8	0	0	0	0	0	112.3	F27 T31 S93 L97 R98 F99	F27-A95 HydrophobicContact CZ-CB 4.49Å; F27-A95 VanDerWaalsContact CZ-O 3.31Å; F27-A95 WeakPolarHBondContact CZ-O 3.46Å; T31-A95 HydrophobicContact CG2-CB 3.83Å; S93-A95 PolarHBondContact O-N 3.32Å; S93-A95 VanDerWaalsContact O-N 3.16Å; A95-L97 VanDerWaalsContact C-N 3.33Å; A95-L97 PolarHBondContact O-N 2.96Å; A95-R98 PolarHBondContact O-N 2.89Å; A95-F99 WeakPolarHBondContact O-CB 3.4Å; A95-F99 PolarHBondContact O-N 3.29Å
96	M	93.4	Very high	87.9	Confident	70 Å²	70	36 Å²	36	35%	0.345	23%	0.228	S	C	.	.	H	α-helix	trans	-65	-39	178.3	-69.3	-60.5	108.8	0	0	112	I77 A91 S93 F99 T100	I77-M96 HydrophobicContact CD1-CB 4.19Å; A91-M96 WeakPolarHBondContact O-CB 3.5Å; A91-M96 WeakPolarHBondContact O-CG 3.23Å; S93-M96 PolarHBondContact O-N 2.92Å; S93-M96 WeakPolarHBondContact OG-CG 3.5Å; S93-M96 PolarHBondContact OG-N 2.94Å; M96-F99 WeakPolarHBondContact O-CB 3.36Å; M96-F99 PolarHBondContact O-N 2.89Å; M96-T100 PolarHBondContact O-N 3.19Å
97	L	95.9	Very high	88.8	Confident	0 Å²	0	32.5 Å²	32.5	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-62.6	-50.5	174.7	-68	172.6	0	0	0	111.1	V45 A48 Q49 I77 S93 T94 A95 F99 T100 Y151	V45-L97 HydrophobicContact CB-CD1 4.42Å; V45-L97 HydrophobicContact CG1-CD1 3.94Å; V45-L97 HydrophobicContact CG2-CD1 4.37Å; A48-L97 HydrophobicContact CB-CD1 3.81Å; A48-L97 HydrophobicContact CB-CD2 3.76Å; A48-L97 HydrophobicContact CB-CG 4.45Å; Q49-L97 HydrophobicContact CG-CD1 4.42Å; I77-L97 HydrophobicContact CD1-CD2 3.79Å; I77-L97 HydrophobicContact CD1-CG 4.45Å; S93-L97 PolarHBondContact O-N 3.37Å; T94-L97 PolarHBondContact O-N 3.45Å; A95-L97 VanDerWaalsContact C-N 3.33Å; A95-L97 PolarHBondContact O-N 2.96Å; L97-F99 PolarHBondContact O-N 3.09Å; L97-T100 PolarHBondContact O-N 2.95Å; L97-T100 VanDerWaalsContact O-N 3.13Å; L97-T100 PolarHBondContact O-OG1 2.79Å; L97-Y151 HydrophobicContact CB-CD1 4.29Å; L97-Y151 HydrophobicContact CB-CD2 3.7Å; L97-Y151 HydrophobicContact CB-CE1 4.29Å; L97-Y151 HydrophobicContact CB-CE2 3.69Å; L97-Y151 HydrophobicContact CB-CG 4Å; L97-Y151 HydrophobicContact CD1-CE1 4.4Å; L97-Y151 HydrophobicContact CD2-CE1 4.47Å; L97-Y151 HydrophobicContact CD2-CE2 4.22Å; L97-Y151 WeakPolarHBondContact O-CD2 3.45Å; L97-Y151 VanDerWaalsContact O-CE2 3.3Å; L97-Y151 WeakPolarHBondContact O-CE2 3.14Å
98	R	97.3	Very high	90.3	Very high	1 Å²	1	27.6 Å²	27.6	0%	0.004	18%	0.183	C	C	.	.	H	α-helix	trans	-59.5	-35.2	175.1	-70.4	175.6	177.4	159.6	3.9	112.7	F27 Q34 D36 E41 T94 A95 T100 N101 F149	F27-R98 HydrophobicContact CE2-CB 3.55Å; F27-R98 HydrophobicContact CZ-CB 4.25Å; Q34-R98 PolarHBondContact O-NH1 3.18Å; Q34-R98 PolarHBondContact O-NH2 3Å; D36-R98 PolarHBondContact O-NH2 3.11Å; D36-R98 VanDerWaalsContact O-NH2 3.08Å; E41-R98 WeakPolarHBondContact OE1-CG 3.48Å; E41-R98 IonicContact OE1-CZ 2.8Å; E41-R98 IonicContact OE1-NE 2.7Å; E41-R98 PolarHBondContact OE1-NE 2.92Å; E41-R98 IonicContact OE1-NH2 3.45Å; E41-R98 IonicContact OE2-CZ 3.76Å; E41-R98 IonicContact OE2-NE 3.41Å; E41-R98 PolarHBondContact OE2-NE 3.41Å; E41-R98 IonicContact OE2-NH2 3.87Å; E41-R98 PolarHBondContact OE2-NH2 3.36Å; T94-R98 HydrophobicContact CG2-CG 4.44Å; T94-R98 WeakPolarHBondContact O-CB 3.4Å; T94-R98 VanDerWaalsContact O-CG 3.3Å; T94-R98 WeakPolarHBondContact O-CG 3.46Å; T94-R98 PolarHBondContact O-N 2.66Å; A95-R98 PolarHBondContact O-N 2.89Å; R98-T100 PolarHBondContact O-N 3.24Å; R98-N101 WeakPolarHBondContact O-CB 3.35Å; R98-N101 PolarHBondContact O-N 3.29Å; R98-F149 WeakPolarHBondContact CD-O 3.25Å
99	F	96.4	Very high	92.1	Very high	52 Å²	52	24.7 Å²	24.7	23%	0.228	15%	0.152	C	C	.	.	H	α-helix	trans	-61.1	-25.8	178.8	-169.8	-105	0	0	0	112.8	F20 F27 A95 M96 L97 N101 V102 L103	F20-F99 HydrophobicContact CE2-CZ 4.25Å; F20-F99 HydrophobicContact CZ-CZ 4.15Å; F27-F99 HydrophobicContact CD1-CD2 4.08Å; F27-F99 HydrophobicContact CE1-CB 4.32Å; F27-F99 AromaticContact CE1-CD2 3.84Å; F27-F99 HydrophobicContact CE1-CD2 3.84Å; F27-F99 HydrophobicContact CZ-CB 4.11Å; F27-F99 HydrophobicContact CZ-CD2 4.41Å; A95-F99 WeakPolarHBondContact O-CB 3.4Å; A95-F99 PolarHBondContact O-N 3.29Å; M96-F99 WeakPolarHBondContact O-CB 3.36Å; M96-F99 PolarHBondContact O-N 2.89Å; L97-F99 PolarHBondContact O-N 3.09Å; F99-N101 PolarHBondContact O-N 3.1Å; F99-V102 HydrophobicContact CD2-CB 4.16Å; F99-V102 HydrophobicContact CD2-CG2 4.32Å; F99-V102 HydrophobicContact CE2-CB 4.37Å; F99-V102 HydrophobicContact CE2-CG1 4.31Å; F99-V102 WeakPolarHBondContact O-CB 3.46Å; F99-V102 PolarHBondContact O-N 3.11Å; F99-L103 HydrophobicContact CD1-CD1 4.42Å; F99-L103 HydrophobicContact CD1-CD2 4.49Å; F99-L103 HydrophobicContact CD1-CG 4.24Å; F99-L103 HydrophobicContact CE1-CD1 4.37Å; F99-L103 HydrophobicContact CE1-CD2 3.81Å; F99-L103 HydrophobicContact CE1-CG 4.05Å; F99-L103 HydrophobicContact CZ-CD2 4.25Å; F99-L103 PolarHBondContact O-N 3.2Å; F99-L103 VanDerWaalsContact O-N 3.12Å
100	T	96.4	Very high	93.8	Very high	3 Å²	3	25.2 Å²	25.2	2%	0.018	14%	0.139	C	C	.	.	H	α-helix	trans	-61.9	-30.4	174.1	67.7	0	0	0	0	112.1	S73 I77 M96 L97 R98 L103 F104	S73-T100 PolarHBondContact OG-OG1 3.43Å; I77-T100 HydrophobicContact CD1-CG2 3.88Å; I77-T100 HydrophobicContact CG1-CG2 4.06Å; M96-T100 PolarHBondContact O-N 3.19Å; L97-T100 PolarHBondContact O-N 2.95Å; L97-T100 VanDerWaalsContact O-N 3.13Å; L97-T100 PolarHBondContact O-OG1 2.79Å; R98-T100 PolarHBondContact O-N 3.24Å; T100-L103 WeakPolarHBondContact O-CB 3.49Å; T100-L103 PolarHBondContact O-N 3.3Å; T100-F104 VanDerWaalsContact O-CD2 3.22Å; T100-F104 WeakPolarHBondContact O-CD2 3.39Å; T100-F104 PolarHBondContact O-N 2.98Å
101	N	97.8	Very high	95.1	Very high	0 Å²	0	22 Å²	22	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-72.7	-31.2	174.4	-78	2.4	0	0	0	112.9	R98 F99 L103 F104 N105 T148 L150 Y152 A155	R98-N101 WeakPolarHBondContact O-CB 3.35Å; R98-N101 PolarHBondContact O-N 3.29Å; F99-N101 PolarHBondContact O-N 3.1Å; N101-L103 VanDerWaalsContact C-N 3.32Å; N101-F104 PolarHBondContact O-N 3.24Å; N101-N105 PolarHBondContact O-N 2.96Å; N101-T148 VanDerWaalsContact CB-O 3.24Å; N101-T148 WeakPolarHBondContact CB-O 3.41Å; N101-L150 PolarHBondContact ND2-O 3.46Å; N101-Y152 PolarHBondContact ND2-N 3.16Å; N101-Y152 VanDerWaalsContact ND2-N 3.2Å; N101-Y152 PolarHBondContact ND2-O 3.07Å; N101-A155 HydrophobicContact CB-CB 3.96Å
102	V	97.6	Very high	96.2	Very high	0 Å²	0	21.8 Å²	21.8	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-63.6	-39.6	170.5	-177.2	0	0	0	0	110.7	F20 F27 F99 N105 C106 T148	F20-V102 HydrophobicContact CD2-CG1 4.25Å; F20-V102 HydrophobicContact CE2-CG1 4.11Å; F27-V102 HydrophobicContact CB-CG2 4.01Å; F27-V102 HydrophobicContact CD2-CG2 3.9Å; F27-V102 HydrophobicContact CG-CG2 3.86Å; F99-V102 HydrophobicContact CD2-CB 4.16Å; F99-V102 HydrophobicContact CD2-CG2 4.32Å; F99-V102 HydrophobicContact CE2-CB 4.37Å; F99-V102 HydrophobicContact CE2-CG1 4.31Å; F99-V102 WeakPolarHBondContact O-CB 3.46Å; F99-V102 PolarHBondContact O-N 3.11Å; V102-N105 WeakPolarHBondContact O-CB 3.46Å; V102-N105 PolarHBondContact O-N 2.89Å; V102-C106 PolarHBondContact O-N 3.33Å; V102-T148 HydrophobicContact CG2-CG2 4.33Å
103	L	97	Very high	96.5	Very high	58 Å²	58	22.8 Å²	22.8	30%	0.304	12%	0.12	S	C	.	.	H	α-helix	trans	-64.1	-43.1	173.8	-60.8	179.8	0	0	0	111.9	I76 F99 T100 N101 N105 C106 G107	I76-L103 HydrophobicContact CG2-CD1 4.19Å; F99-L103 HydrophobicContact CD1-CD1 4.42Å; F99-L103 HydrophobicContact CD1-CD2 4.49Å; F99-L103 HydrophobicContact CD1-CG 4.24Å; F99-L103 HydrophobicContact CE1-CD1 4.37Å; F99-L103 HydrophobicContact CE1-CD2 3.81Å; F99-L103 HydrophobicContact CE1-CG 4.05Å; F99-L103 HydrophobicContact CZ-CD2 4.25Å; F99-L103 PolarHBondContact O-N 3.2Å; F99-L103 VanDerWaalsContact O-N 3.12Å; T100-L103 WeakPolarHBondContact O-CB 3.49Å; T100-L103 PolarHBondContact O-N 3.3Å; N101-L103 VanDerWaalsContact C-N 3.32Å; L103-N105 VanDerWaalsContact C-N 3.26Å; L103-N105 PolarHBondContact O-N 2.89Å; L103-C106 WeakPolarHBondContact O-CB 3.41Å; L103-C106 PolarHBondContact O-N 2.96Å; L103-G107 PolarHBondContact O-N 3.33Å
104	F	98.1	Very high	96.7	Very high	12 Å²	12	22.8 Å²	22.8	5%	0.053	12%	0.117	C	C	.	.	H	α-helix	trans	-60.7	-35.4	173.1	-75	-55.1	0	0	0	112.4	V72 T100 N101 G107 N108 A155 F159 F160 F186	V72-F104 HydrophobicContact CB-CZ 4.38Å; V72-F104 HydrophobicContact CG1-CE1 4.44Å; V72-F104 HydrophobicContact CG1-CE2 4.4Å; V72-F104 HydrophobicContact CG1-CZ 3.64Å; T100-F104 VanDerWaalsContact O-CD2 3.22Å; T100-F104 WeakPolarHBondContact O-CD2 3.39Å; T100-F104 PolarHBondContact O-N 2.98Å; N101-F104 PolarHBondContact O-N 3.24Å; F104-G107 CarbonylContact O-C 3.13Å; F104-G107 PolarHBondContact O-N 2.95Å; F104-N108 WeakPolarHBondContact O-CB 3.47Å; F104-N108 PolarHBondContact O-N 3.06Å; F104-N108 PolarHBondContact O-ND2 3.33Å; F104-A155 HydrophobicContact CB-CB 3.97Å; F104-F159 HydrophobicContact CD1-CB 3.75Å; F104-F159 AromaticContact CD1-CD1 3.86Å; F104-F159 HydrophobicContact CD1-CD1 3.86Å; F104-F159 HydrophobicContact CD1-CD2 4.32Å; F104-F159 AromaticContact CD1-CG 3.71Å; F104-F159 HydrophobicContact CD1-CG 3.71Å; F104-F159 HydrophobicContact CE1-CB 4.39Å; F104-F159 AromaticContact CE1-CD1 3.89Å; F104-F159 HydrophobicContact CE1-CD1 3.89Å; F104-F159 HydrophobicContact CE1-CE1 4.5Å; F104-F159 HydrophobicContact CE1-CG 4.22Å; F104-F159 HydrophobicContact CG-CB 4.46Å; F104-F160 AromaticContact CE1-CE2 3.91Å; F104-F160 HydrophobicContact CE1-CE2 3.91Å; F104-F160 HydrophobicContact CE1-CZ 4.39Å; F104-F160 HydrophobicContact CZ-CE2 4.09Å; F104-F186 HydrophobicContact CE2-CE1 4.03Å; F104-F186 AromaticContact CE2-CZ 3.87Å; F104-F186 HydrophobicContact CE2-CZ 3.87Å; F104-F186 HydrophobicContact CZ-CE1 4.21Å; F104-F186 AromaticContact CZ-CZ 3.65Å; F104-F186 HydrophobicContact CZ-CZ 3.65Å
105	N	97.6	Very high	96.8	Very high	1 Å²	1	21.8 Å²	21.8	1%	0.005	11%	0.111	C	C	.	.	H	α-helix	trans	-63.6	-39.5	175.2	-177.9	67.8	0	0	0	112.9	N19 S23 N101 V102 L103 G107 N108 F109 T148	N19-N105 PolarHBondContact ND2-ND2 3.43Å; S23-N105 PolarHBondContact OG-ND2 2.97Å; N101-N105 PolarHBondContact O-N 2.96Å; V102-N105 WeakPolarHBondContact O-CB 3.46Å; V102-N105 PolarHBondContact O-N 2.89Å; L103-N105 VanDerWaalsContact C-N 3.26Å; L103-N105 PolarHBondContact O-N 2.89Å; N105-G107 VanDerWaalsContact C-N 3.35Å; N105-N108 PolarHBondContact O-N 3.1Å; N105-F109 PolarHBondContact O-N 3.18Å; N105-T148 HydrophobicContact CB-CG2 3.41Å; N105-T148 VanDerWaalsContact CB-CG2 3.41Å
106	C	96.6	Very high	96.8	Very high	25 Å²	25	20.5 Å²	20.5	17%	0.169	10%	0.1	C	C	.	.	H	α-helix	trans	-61.7	-44.6	171	-68.4	0	0	0	0	111.7	F20 V102 L103 N108 F109 Y110	F20-C106 WeakPolarHBondContact CD2-SG 3.22Å; V102-C106 PolarHBondContact O-N 3.33Å; L103-C106 WeakPolarHBondContact O-CB 3.41Å; L103-C106 PolarHBondContact O-N 2.96Å; C106-N108 VanDerWaalsContact C-N 3.35Å; C106-N108 PolarHBondContact O-N 3.18Å; C106-F109 WeakPolarHBondContact O-CB 3.34Å; C106-F109 PolarHBondContact O-N 2.98Å; C106-Y110 PolarHBondContact O-N 3.45Å
107	G	97.6	Very high	96.6	Very high	15 Å²	15	18.8 Å²	18.8	16%	0.155	10%	0.095	C	C	.	.	H	α-helix	trans	-59.7	-43.8	174.2	0	0	0	0	0	112.7	L103 F104 N105 Y110 L111	L103-G107 PolarHBondContact O-N 3.33Å; F104-G107 CarbonylContact O-C 3.13Å; F104-G107 PolarHBondContact O-N 2.95Å; N105-G107 VanDerWaalsContact C-N 3.35Å; G107-Y110 PolarHBondContact O-N 3.39Å; G107-L111 WeakPolarHBondContact O-CB 3.2Å; G107-L111 VanDerWaalsContact O-CG 3.28Å; G107-L111 WeakPolarHBondContact O-CG 3.49Å; G107-L111 PolarHBondContact O-N 3.33Å
108	N	98.3	Very high	96.5	Very high	2 Å²	2	22.7 Å²	22.7	1%	0.011	11%	0.112	C	C	.	.	H	α-helix	trans	-61.9	-45.3	177.3	-74.9	-30.4	0	0	0	111.4	F104 N105 C106 Y110 L111 L112 A155 F159	F104-N108 WeakPolarHBondContact O-CB 3.47Å; F104-N108 PolarHBondContact O-N 3.06Å; F104-N108 PolarHBondContact O-ND2 3.33Å; N105-N108 PolarHBondContact O-N 3.1Å; C106-N108 VanDerWaalsContact C-N 3.35Å; C106-N108 PolarHBondContact O-N 3.18Å; N108-Y110 VanDerWaalsContact C-N 3.32Å; N108-Y110 PolarHBondContact O-N 3.17Å; N108-L111 PolarHBondContact O-N 2.89Å; N108-L112 VanDerWaalsContact O-CB 3.28Å; N108-L112 WeakPolarHBondContact O-CB 3.49Å; N108-L112 WeakPolarHBondContact O-CD1 3.5Å; N108-L112 WeakPolarHBondContact O-CG 3.44Å; N108-L112 PolarHBondContact O-N 3.35Å; N108-A155 PolarHBondContact ND2-O 2.98Å; N108-F159 WeakPolarHBondContact OD1-CA 3.37Å; N108-F159 VanDerWaalsContact OD1-CB 3.32Å; N108-F159 WeakPolarHBondContact OD1-CB 3.43Å; N108-F159 PolarHBondContact OD1-N 3.15Å; N108-F159 VanDerWaalsContact OD1-N 3.1Å
109	F	97.6	Very high	96.2	Very high	2 Å²	2	24 Å²	24	1%	0.009	12%	0.119	C	C	.	.	H	α-helix	trans	-55.1	-49.1	173.8	-177.4	-83.7	0	0	0	111.3	F12 L15 C16 N19 N105 C106 Y113 T135 V136 S139	F12-F109 HydrophobicContact CD2-CE1 4.01Å; F12-F109 AromaticContact CE2-CD1 3.96Å; F12-F109 HydrophobicContact CE2-CD1 3.96Å; F12-F109 AromaticContact CE2-CE1 3.44Å; F12-F109 HydrophobicContact CE2-CE1 3.44Å; F12-F109 VanDerWaalsContact CE2-CE1 3.44Å; F12-F109 HydrophobicContact CE2-CZ 4.43Å; F12-F109 HydrophobicContact CZ-CD1 4.23Å; F12-F109 HydrophobicContact CZ-CE1 4.05Å; L15-F109 HydrophobicContact CB-CZ 4Å; C16-F109 HydrophobicContact CB-CD1 4.16Å; C16-F109 HydrophobicContact CB-CE1 3.95Å; N19-F109 HydrophobicContact CB-CD2 4.17Å; N19-F109 HydrophobicContact CB-CE2 4.29Å; N105-F109 PolarHBondContact O-N 3.18Å; C106-F109 WeakPolarHBondContact O-CB 3.34Å; C106-F109 PolarHBondContact O-N 2.98Å; F109-Y113 PolarHBondContact O-N 3.24Å; F109-Y113 VanDerWaalsContact O-N 3.15Å; F109-T135 HydrophobicContact CD1-CG2 4.41Å; F109-T135 HydrophobicContact CD2-CG2 4.2Å; F109-T135 HydrophobicContact CE1-CG2 4.29Å; F109-T135 HydrophobicContact CE2-CG2 4.04Å; F109-T135 HydrophobicContact CG-CG2 4.35Å; F109-T135 HydrophobicContact CZ-CG2 4.08Å; F109-T135 WeakPolarHBondContact O-CG2 3.32Å; F109-V136 HydrophobicContact CE2-CG2 3.9Å; F109-V136 HydrophobicContact CZ-CG2 4.23Å; F109-S139 VanDerWaalsContact CD2-OG 3.29Å; F109-S139 WeakPolarHBondContact CD2-OG 3.44Å
110	Y	97.2	Very high	95.8	Very high	115 Å²	115	22.8 Å²	22.8	45%	0.451	11%	0.114	S	C	.	.	H	α-helix	trans	-63.3	-48	-179.8	-175.6	-100.8	0	0	0	112.4	F12 C106 G107 N108 L112 Y113 L114	F12-Y110 AromaticContact CE1-CD2 3.66Å; F12-Y110 HydrophobicContact CE1-CD2 3.66Å; F12-Y110 AromaticContact CE1-CE2 3.87Å; F12-Y110 HydrophobicContact CE1-CE2 3.87Å; F12-Y110 AromaticContact CZ-CD2 3.51Å; F12-Y110 HydrophobicContact CZ-CD2 3.51Å; F12-Y110 HydrophobicContact CZ-CE2 4.1Å; F12-Y110 HydrophobicContact CZ-CG 4.43Å; C106-Y110 PolarHBondContact O-N 3.45Å; G107-Y110 PolarHBondContact O-N 3.39Å; N108-Y110 VanDerWaalsContact C-N 3.32Å; N108-Y110 PolarHBondContact O-N 3.17Å; Y110-L112 PolarHBondContact O-N 2.84Å; Y110-Y113 WeakPolarHBondContact O-CB 3.12Å; Y110-Y113 PolarHBondContact O-N 3.47Å; Y110-L114 HydrophobicContact CD1-CD1 3.95Å; Y110-L114 HydrophobicContact CD1-CG 4.42Å; Y110-L114 HydrophobicContact CE1-CD1 3.35Å; Y110-L114 HydrophobicContact CE1-CG 4.07Å; Y110-L114 PolarHBondContact O-N 2.93Å; Y110-L114 VanDerWaalsContact O-N 3.09Å
111	L	98.2	Very high	94.9	Very high	6 Å²	6	28.7 Å²	28.7	3%	0.031	14%	0.141	C	C	.	.	H	α-helix	trans	-65	-40.2	179.4	-71	172.2	0	0	0	112.4	G107 N108 Y113 L114 L115 F159 L162 F163 L166	G107-L111 WeakPolarHBondContact O-CB 3.2Å; G107-L111 VanDerWaalsContact O-CG 3.28Å; G107-L111 WeakPolarHBondContact O-CG 3.49Å; G107-L111 PolarHBondContact O-N 3.33Å; N108-L111 PolarHBondContact O-N 2.89Å; L111-Y113 VanDerWaalsContact C-N 3.31Å; L111-Y113 PolarHBondContact O-N 2.91Å; L111-L114 PolarHBondContact O-N 3.15Å; L111-L115 WeakPolarHBondContact O-CB 3.43Å; L111-L115 VanDerWaalsContact O-CG 3.29Å; L111-L115 WeakPolarHBondContact O-CG 3.41Å; L111-L115 PolarHBondContact O-N 2.91Å; L111-F159 HydrophobicContact CD1-CD2 3.44Å; L111-F159 VanDerWaalsContact CD1-CD2 3.44Å; L111-F159 HydrophobicContact CD1-CE2 3.45Å; L111-F159 VanDerWaalsContact CD1-CE2 3.45Å; L111-F159 HydrophobicContact CD1-CG 4.14Å; L111-F159 HydrophobicContact CD1-CZ 4.16Å; L111-F159 WeakPolarHBondContact CD1-O 3.42Å; L111-F159 HydrophobicContact CG-CE2 4.25Å; L111-L162 HydrophobicContact CB-CB 4.23Å; L111-L162 HydrophobicContact CD1-CB 4.16Å; L111-F163 HydrophobicContact CD1-CB 3.75Å; L111-F163 HydrophobicContact CD1-CG 4.32Å; L111-F163 HydrophobicContact CD2-CB 4.09Å; L111-F163 HydrophobicContact CD2-CD2 3.94Å; L111-F163 HydrophobicContact CD2-CG 4.01Å; L111-L166 HydrophobicContact CD2-CD2 3.77Å
112	L	97.8	Very high	93.3	Very high	2 Å²	2	38.4 Å²	38.4	1%	0.01	18%	0.178	C	C	.	.	H	α-helix	trans	-60	-42.9	175.7	-75.4	169.2	0	0	0	111	N108 Y110 L115 I116 T135 L138 L162 L431	N108-L112 VanDerWaalsContact O-CB 3.28Å; N108-L112 WeakPolarHBondContact O-CB 3.49Å; N108-L112 WeakPolarHBondContact O-CD1 3.5Å; N108-L112 WeakPolarHBondContact O-CG 3.44Å; N108-L112 PolarHBondContact O-N 3.35Å; Y110-L112 PolarHBondContact O-N 2.84Å; L112-L115 PolarHBondContact O-N 3.17Å; L112-I116 WeakPolarHBondContact O-CB 3.44Å; L112-I116 WeakPolarHBondContact O-CD1 3.36Å; L112-I116 WeakPolarHBondContact O-CG1 3.5Å; L112-I116 PolarHBondContact O-N 3.12Å; L112-T135 HydrophobicContact CB-CG2 4.23Å; L112-L138 HydrophobicContact CD1-CB 3.89Å; L112-L138 HydrophobicContact CD2-CB 4.34Å; L112-L138 HydrophobicContact CD2-CD1 4.43Å; L112-L162 HydrophobicContact CD2-CD1 3.87Å; L112-L162 HydrophobicContact CD2-CD2 4.28Å; L112-L162 HydrophobicContact CG-CD1 3.92Å; L112-L431 HydrophobicContact CD2-CD1 4.33Å; L112-L431 HydrophobicContact CD2-CD2 4.03Å; L112-L431 HydrophobicContact CD2-CG 4.39Å
113	Y	95	Very high	91.3	Very high	29 Å²	29	45 Å²	45	11%	0.114	21%	0.213	C	C	.	.	H	α-helix	trans	-61.6	-46.6	175.7	174.4	-103	0	0	0	112.5	E8 F12 F109 Y110 L111 I116 S117 I132	E8-Y113 VanDerWaalsContact CD-OH 3.24Å; E8-Y113 VanDerWaalsContact CG-OH 3.28Å; E8-Y113 WeakPolarHBondContact CG-OH 3.28Å; E8-Y113 PolarHBondContact OE1-OH 3.32Å; F12-Y113 AromaticContact CD2-CD1 3.75Å; F12-Y113 HydrophobicContact CD2-CD1 3.75Å; F12-Y113 AromaticContact CD2-CD2 3.65Å; F12-Y113 HydrophobicContact CD2-CD2 3.65Å; F12-Y113 AromaticContact CD2-CE1 3.99Å; F12-Y113 HydrophobicContact CD2-CE1 3.99Å; F12-Y113 AromaticContact CD2-CE2 3.9Å; F12-Y113 HydrophobicContact CD2-CE2 3.9Å; F12-Y113 AromaticContact CD2-CG 3.57Å; F12-Y113 HydrophobicContact CD2-CG 3.57Å; F12-Y113 HydrophobicContact CE1-CD1 4.37Å; F12-Y113 VanDerWaalsContact CE2-CB 3.41Å; F12-Y113 AromaticContact CE2-CD1 3.47Å; F12-Y113 HydrophobicContact CE2-CD1 3.47Å; F12-Y113 VanDerWaalsContact CE2-CD1 3.47Å; F12-Y113 AromaticContact CE2-CD2 3.82Å; F12-Y113 HydrophobicContact CE2-CD2 3.82Å; F12-Y113 HydrophobicContact CE2-CE1 4.15Å; F12-Y113 HydrophobicContact CE2-CE2 4.45Å; F12-Y113 AromaticContact CE2-CG 3.27Å; F12-Y113 HydrophobicContact CE2-CG 3.27Å; F12-Y113 HydrophobicContact CG-CD1 4.32Å; F12-Y113 HydrophobicContact CG-CE1 4.2Å; F12-Y113 HydrophobicContact CG-CE2 4.5Å; F12-Y113 AromaticContact CZ-CD1 3.81Å; F12-Y113 HydrophobicContact CZ-CD1 3.81Å; F12-Y113 HydrophobicContact CZ-CE1 4.48Å; F12-Y113 HydrophobicContact CZ-CG 4.03Å; F109-Y113 PolarHBondContact O-N 3.24Å; F109-Y113 VanDerWaalsContact O-N 3.15Å; Y110-Y113 WeakPolarHBondContact O-CB 3.12Å; Y110-Y113 PolarHBondContact O-N 3.47Å; L111-Y113 VanDerWaalsContact C-N 3.31Å; L111-Y113 PolarHBondContact O-N 2.91Å; Y113-I116 PolarHBondContact O-N 3.25Å; Y113-S117 VanDerWaalsContact O-CB 3.32Å; Y113-S117 WeakPolarHBondContact O-CB 3.48Å; Y113-S117 PolarHBondContact O-N 3.03Å; Y113-S117 PolarHBondContact O-OG 3.34Å; Y113-I132 HydrophobicContact CE2-CG1 4.43Å
114	L	95.3	Very high	89.6	Confident	37 Å²	37	47.9 Å²	47.9	19%	0.194	22%	0.223	C	C	.	.	H	α-helix	trans	-62.9	-43.9	177.7	-68.4	-174	0	0	0	111.9	Y110 L111 S117 K118 L166	Y110-L114 HydrophobicContact CD1-CD1 3.95Å; Y110-L114 HydrophobicContact CD1-CG 4.42Å; Y110-L114 HydrophobicContact CE1-CD1 3.35Å; Y110-L114 HydrophobicContact CE1-CG 4.07Å; Y110-L114 PolarHBondContact O-N 2.93Å; Y110-L114 VanDerWaalsContact O-N 3.09Å; L111-L114 PolarHBondContact O-N 3.15Å; L114-S117 PolarHBondContact O-N 2.89Å; L114-K118 WeakPolarHBondContact O-CB 3.29Å; L114-K118 PolarHBondContact O-N 3.04Å; L114-L166 HydrophobicContact CB-CD1 4.12Å; L114-L166 HydrophobicContact CB-CD2 3.92Å; L114-L166 HydrophobicContact CD1-CD2 3.77Å
115	L	96.8	Very high	87.6	Confident	0 Å²	0	51.3 Å²	51.3	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-62.3	-47.7	177.1	-78.1	168.3	0	0	0	111.7	L111 L112 S117 K118 L119 L162 Y165 L166 L169 L431	L111-L115 WeakPolarHBondContact O-CB 3.43Å; L111-L115 VanDerWaalsContact O-CG 3.29Å; L111-L115 WeakPolarHBondContact O-CG 3.41Å; L111-L115 PolarHBondContact O-N 2.91Å; L112-L115 PolarHBondContact O-N 3.17Å; L115-S117 VanDerWaalsContact C-N 3.29Å; L115-S117 PolarHBondContact O-N 3.46Å; L115-K118 PolarHBondContact O-N 3.28Å; L115-L119 VanDerWaalsContact O-CB 3.31Å; L115-L119 WeakPolarHBondContact O-CB 3.48Å; L115-L119 VanDerWaalsContact O-CG 3.28Å; L115-L119 WeakPolarHBondContact O-CG 3.45Å; L115-L119 PolarHBondContact O-N 2.87Å; L115-L162 HydrophobicContact CD1-CB 3.92Å; L115-L162 HydrophobicContact CD1-CD2 3.69Å; L115-L162 HydrophobicContact CD1-CG 4.32Å; L115-Y165 HydrophobicContact CD2-CD1 3.67Å; L115-Y165 HydrophobicContact CD2-CE1 4.19Å; L115-Y165 HydrophobicContact CD2-CG 4.47Å; L115-L166 HydrophobicContact CD2-CB 3.79Å; L115-L166 HydrophobicContact CD2-CD1 3.78Å; L115-L166 HydrophobicContact CD2-CG 4.41Å; L115-L166 HydrophobicContact CG-CB 4.2Å; L115-L166 HydrophobicContact CG-CD1 4.06Å; L115-L169 HydrophobicContact CD2-CD1 3.78Å; L115-L431 HydrophobicContact CB-CD2 4.02Å; L115-L431 HydrophobicContact CD1-CD1 3.92Å
116	I	94.3	Very high	86	Confident	1 Å²	1	61.7 Å²	61.7	1%	0.005	28%	0.284	C	S	.	.	H	α-helix	trans	-60.2	-43.6	177.3	-71.8	165.4	0	0	0	110	L112 Y113 K118 L119 H120 R131 C134 T135 L138 L431 L435	L112-I116 WeakPolarHBondContact O-CB 3.44Å; L112-I116 WeakPolarHBondContact O-CD1 3.36Å; L112-I116 WeakPolarHBondContact O-CG1 3.5Å; L112-I116 PolarHBondContact O-N 3.12Å; Y113-I116 PolarHBondContact O-N 3.25Å; I116-K118 PolarHBondContact O-N 3.03Å; I116-L119 PolarHBondContact O-N 3.13Å; I116-H120 WeakPolarHBondContact O-CB 3.3Å; I116-H120 PolarHBondContact O-CD2 3.17Å; I116-H120 PolarHBondContact O-N 3.37Å; I116-R131 HydrophobicContact CG2-CB 3.8Å; I116-R131 HydrophobicContact CG2-CG 3.65Å; I116-C134 HydrophobicContact CD1-CB 4.17Å; I116-T135 WeakPolarHBondContact CD1-OG1 3.26Å; I116-L138 HydrophobicContact CD1-CD1 4.36Å; I116-L431 HydrophobicContact CD1-CD2 4.4Å; I116-L431 HydrophobicContact CG1-CD2 3.67Å; I116-L435 HydrophobicContact CG2-CD1 4.44Å; I116-L435 HydrophobicContact CG2-CD2 4.35Å
117	S	91.1	Very high	85	Confident	34 Å²	34	61.1 Å²	61.1	24%	0.238	28%	0.279	C	S	.	.	H	α-helix	trans	-63.5	-40.5	178.3	-60.3	0	0	0	0	112.3	Y113 L114 L115	Y113-S117 VanDerWaalsContact O-CB 3.32Å; Y113-S117 WeakPolarHBondContact O-CB 3.48Å; Y113-S117 PolarHBondContact O-N 3.03Å; Y113-S117 PolarHBondContact O-OG 3.34Å; L114-S117 PolarHBondContact O-N 2.89Å; L115-S117 VanDerWaalsContact C-N 3.29Å; L115-S117 PolarHBondContact O-N 3.46Å
118	K	92.7	Very high	84.4	Confident	82 Å²	82	61.1 Å²	61.1	36%	0.357	28%	0.275	S	S	.	.	H	α-helix	trans	-68.8	-44.3	177.1	-176.7	66.6	175.9	-170.4	0	112.3	L114 L115 I116 L169 Y170	L114-K118 WeakPolarHBondContact O-CB 3.29Å; L114-K118 PolarHBondContact O-N 3.04Å; L115-K118 PolarHBondContact O-N 3.28Å; I116-K118 PolarHBondContact O-N 3.03Å; K118-L169 WeakPolarHBondContact CE-O 3.31Å; K118-L169 HydrophobicContact CG-CB 4.04Å; K118-L169 HydrophobicContact CG-CD1 4.11Å; K118-L169 PolarHBondContact NZ-O 3.23Å; K118-Y170 HydrophobicContact CD-CE1 4.39Å
119	L	91.6	Very high	83.8	Confident	29 Å²	29	66.5 Å²	66.5	15%	0.152	30%	0.299	C	S	.	.	H	α-helix	trans	-76.2	-31.3	-176	-71	170.6	0	0	0	113.1	L115 I116 Y165 L169 L431	L115-L119 VanDerWaalsContact O-CB 3.31Å; L115-L119 WeakPolarHBondContact O-CB 3.48Å; L115-L119 VanDerWaalsContact O-CG 3.28Å; L115-L119 WeakPolarHBondContact O-CG 3.45Å; L115-L119 PolarHBondContact O-N 2.87Å; I116-L119 PolarHBondContact O-N 3.13Å; L119-Y165 HydrophobicContact CD1-CE1 4.32Å; L119-L169 HydrophobicContact CD2-CD1 3.77Å; L119-L169 HydrophobicContact CD2-CD2 4.28Å; L119-L169 HydrophobicContact CG-CD1 3.98Å; L119-L431 HydrophobicContact CD1-CB 3.99Å
120	H	88.3	Confident	83.4	Confident	25 Å²	25	69.3 Å²	69.3	12%	0.116	31%	0.31	C	S	.	.			trans	-118.7	61.2	-176	-57	-77.4	0	0	0	110.5	I116 L127 L431 M433 L435	I116-H120 WeakPolarHBondContact O-CB 3.3Å; I116-H120 PolarHBondContact O-CD2 3.17Å; I116-H120 PolarHBondContact O-N 3.37Å; H120-L127 HydrophobicContact CB-CD2 4.27Å; H120-L127 WeakPolarHBondContact O-CD2 3.36Å; H120-L431 PolarHBondContact NE2-O 2.99Å; H120-M433 PolarHBondContact CE1-O 3.26Å; H120-M433 PolarHBondContact NE2-O 3.33Å; H120-L435 HydrophobicContact CB-CD1 3.8Å; H120-L435 HydrophobicContact CB-CG 4.31Å
121	H	77.1	Confident	83.1	Confident	127 Å²	127	64.8 Å²	64.8	59%	0.588	29%	0.292	S	S	*	.			trans	-85.7	-4.4	-176.7	66.6	-88.8	0	0	0	114.7
122	R	64.8	Low	82.8	Confident	204 Å²	204	65.2 Å²	65.2	77%	0.77	29%	0.294	S	S	*	.	S	Bend	trans	-90.3	117	-174.9	-65.5	-174.1	173.1	-174.4	-5	110.7	L127	R122-L127 WeakPolarHBondContact O-CD2 3.24Å
123	D	54.2	Low	82.5	Confident	139 Å²	139	66.7 Å²	66.7	74%	0.743	30%	0.302	S	S	*	.			trans	75.9	116.7	-173.4	-73.8	-36.6	0	0	0	117.4	L127	D123-L127 WeakPolarHBondContact O-CB 3.37Å; D123-L127 VanDerWaalsContact O-CD2 3.29Å; D123-L127 WeakPolarHBondContact O-CD2 3.5Å
124	K	61.1	Low	82.5	Confident	118 Å²	118	65.4 Å²	65.4	51%	0.513	30%	0.297	S	S	.	.	S	Bend	trans	-82.1	-43.2	-165.3	-69.4	-171.7	176.4	-170.1	0	115.4	M1	M1-K124 HydrophobicContact SD-CD 4.3Å; M1-K124 PolarHBondContact SD-NZ 3.13Å
125	T	57.3	Low	82.5	Confident	84 Å²	84	63.7 Å²	63.7	52%	0.515	29%	0.288	S	S	.	.	H	α-helix	trans	-89	-51.8	-161.9	-34.9	0	0	0	0	114.5	M4 L127 M128	M4-T125 HydrophobicContact CE-CG2 4.26Å; M4-T125 HydrophobicContact SD-CG2 3.82Å; T125-L127 PolarHBondContact O-N 3.24Å; T125-L127 VanDerWaalsContact O-N 3.16Å; T125-M128 PolarHBondContact O-N 2.83Å
126	R	63.1	Low	82.5	Confident	220 Å²	220	64.8 Å²	64.8	83%	0.83	30%	0.295	S	S	*	.	H	α-helix	trans	-68.4	-12.3	175.9	-76	-176.8	-179.8	176.4	0.5	113.1	R130	R126-R130 WeakPolarHBondContact O-CD 3.45Å
127	L	76.6	Confident	82.6	Confident	13 Å²	13	64.8 Å²	64.8	7%	0.068	29%	0.294	C	S	.	.	H	α-helix	trans	-90.4	-26.3	-175.4	-150.2	73.8	0	0	0	112.4	H120 R122 D123 T125 R130 R131 L435	H120-L127 HydrophobicContact CB-CD2 4.27Å; H120-L127 WeakPolarHBondContact O-CD2 3.36Å; R122-L127 WeakPolarHBondContact O-CD2 3.24Å; D123-L127 WeakPolarHBondContact O-CB 3.37Å; D123-L127 VanDerWaalsContact O-CD2 3.29Å; D123-L127 WeakPolarHBondContact O-CD2 3.5Å; T125-L127 PolarHBondContact O-N 3.24Å; T125-L127 VanDerWaalsContact O-N 3.16Å; L127-R130 CarbonylContact O-C 3.59Å; L127-R130 WeakPolarHBondContact O-CB 3.47Å; L127-R130 PolarHBondContact O-N 3.38Å; L127-R130 VanDerWaalsContact O-N 3.13Å; L127-R131 HydrophobicContact CG-CG 4.27Å; L127-R131 WeakPolarHBondContact O-CG 3.3Å; L127-R131 PolarHBondContact O-N 3.27Å; L127-L435 HydrophobicContact CD1-CD1 3.76Å; L127-L435 HydrophobicContact CD2-CD1 4.44Å; L127-L435 HydrophobicContact CG-CD1 3.89Å
128	M	83.7	Confident	82.9	Confident	14 Å²	14	63.1 Å²	63.1	7%	0.069	28%	0.283	C	S	.	.	H	α-helix	trans	-52.6	-61.6	-179.7	-176.5	-144.2	-66.4	0	0	112.2	E8 I11 T125 R130 R131 I132	E8-M128 HydrophobicContact CB-CE 4.03Å; E8-M128 HydrophobicContact CB-CG 4.12Å; E8-M128 HydrophobicContact CB-SD 4.18Å; E8-M128 HydrophobicContact CG-CG 3.78Å; E8-M128 HydrophobicContact CG-SD 4.41Å; I11-M128 HydrophobicContact CD1-SD 4.2Å; T125-M128 PolarHBondContact O-N 2.83Å; M128-R130 PolarHBondContact O-N 2.88Å; M128-R130 VanDerWaalsContact O-N 3.17Å; M128-R131 WeakPolarHBondContact O-CB 3.4Å; M128-R131 PolarHBondContact O-N 2.72Å; M128-I132 HydrophobicContact CG-CD1 3.81Å; M128-I132 WeakPolarHBondContact O-CG1 3.41Å; M128-I132 PolarHBondContact O-N 3.18Å; M128-I132 HydrophobicContact SD-CD1 4.15Å
129	F	85.8	Confident	83.1	Confident	115 Å²	115	59.3 Å²	59.3	50%	0.504	27%	0.266	S	S	.	.	H	α-helix	trans	-58.9	-32.5	179.7	-67	-73.6	0	0	0	112.8	L133 L438	F129-L133 VanDerWaalsContact O-CB 3.22Å; F129-L133 WeakPolarHBondContact O-CB 3.32Å; F129-L133 PolarHBondContact O-N 3.35Å; F129-L438 HydrophobicContact CB-CD1 4.27Å; F129-L438 HydrophobicContact CB-CD2 3.86Å
130	R	90.6	Very high	83.3	Confident	62 Å²	62	58.6 Å²	58.6	23%	0.234	26%	0.264	C	S	.	.	H	α-helix	trans	-70.7	-41.7	176.5	-66	165.9	70	-168.2	5.7	111.4	R126 L127 M128 C134 L435 S436 L438 L441	R126-R130 WeakPolarHBondContact O-CD 3.45Å; L127-R130 CarbonylContact O-C 3.59Å; L127-R130 WeakPolarHBondContact O-CB 3.47Å; L127-R130 PolarHBondContact O-N 3.38Å; L127-R130 VanDerWaalsContact O-N 3.13Å; M128-R130 PolarHBondContact O-N 2.88Å; M128-R130 VanDerWaalsContact O-N 3.17Å; R130-C134 WeakPolarHBondContact O-CB 3.35Å; R130-C134 PolarHBondContact O-N 3.42Å; R130-L435 HydrophobicContact CB-CD1 4.42Å; R130-L435 VanDerWaalsContact NH2-C 3.3Å; R130-L435 PolarHBondContact NH2-O 3.42Å; R130-S436 PolarHBondContact NE-O 2.81Å; R130-S436 PolarHBondContact NH2-O 3.49Å; R130-L438 HydrophobicContact CB-CD2 4.41Å; R130-L438 HydrophobicContact CG-CD2 3.67Å; R130-L438 HydrophobicContact CG-CG 3.87Å; R130-L441 HydrophobicContact CB-CD1 3.81Å; R130-L441 HydrophobicContact CG-CD1 4.11Å; R130-L441 WeakPolarHBondContact O-CD1 3.42Å
131	R	90.4	Very high	83.8	Confident	20 Å²	20	57.4 Å²	57.4	8%	0.075	26%	0.258	C	S	.	.	H	α-helix	trans	-62.4	-47.8	175.3	-69.7	-167.2	-65.9	-95.2	0.3	110.4	E8 I116 L127 M128 C134 T135 L435	E8-R131 VanDerWaalsContact CD-NH2 3.25Å; E8-R131 IonicContact OE1-CZ 3.82Å; E8-R131 IonicContact OE1-NE 3.17Å; E8-R131 PolarHBondContact OE1-NE 3.33Å; E8-R131 IonicContact OE1-NH2 3.38Å; E8-R131 PolarHBondContact OE1-NH2 2.96Å; E8-R131 IonicContact OE2-NH2 3.16Å; E8-R131 PolarHBondContact OE2-NH2 3.48Å; I116-R131 HydrophobicContact CG2-CB 3.8Å; I116-R131 HydrophobicContact CG2-CG 3.65Å; L127-R131 HydrophobicContact CG-CG 4.27Å; L127-R131 WeakPolarHBondContact O-CG 3.3Å; L127-R131 PolarHBondContact O-N 3.27Å; M128-R131 WeakPolarHBondContact O-CB 3.4Å; M128-R131 PolarHBondContact O-N 2.72Å; R131-C134 PolarHBondContact O-N 2.88Å; R131-T135 WeakPolarHBondContact O-CB 3.2Å; R131-T135 PolarHBondContact O-N 2.84Å; R131-T135 PolarHBondContact O-OG1 3.24Å; R131-L435 HydrophobicContact CG-CD1 3.98Å
132	I	90.8	Very high	84.8	Confident	14 Å²	14	51.4 Å²	51.4	7%	0.072	23%	0.23	C	C	.	.	H	α-helix	trans	-61.8	-53.3	-179.5	-70.6	174.4	0	0	0	110.5	I11 L15 Y113 M128 C134 T135 V136	I11-I132 HydrophobicContact CB-CD1 4.33Å; I11-I132 HydrophobicContact CG2-CD1 3.75Å; L15-I132 HydrophobicContact CD1-CG2 3.07Å; Y113-I132 HydrophobicContact CE2-CG1 4.43Å; M128-I132 HydrophobicContact CG-CD1 3.81Å; M128-I132 WeakPolarHBondContact O-CG1 3.41Å; M128-I132 PolarHBondContact O-N 3.18Å; M128-I132 HydrophobicContact SD-CD1 4.15Å; I132-C134 VanDerWaalsContact C-N 3.33Å; I132-C134 PolarHBondContact O-N 3.43Å; I132-T135 WeakPolarHBondContact O-CB 3.24Å; I132-T135 PolarHBondContact O-N 2.93Å; I132-T135 VanDerWaalsContact O-N 3.09Å; I132-V136 WeakPolarHBondContact O-CG2 3.29Å; I132-V136 PolarHBondContact O-N 2.89Å
133	L	92.9	Very high	86.4	Confident	34 Å²	34	41.7 Å²	41.7	18%	0.178	19%	0.193	C	C	.	.	H	α-helix	trans	-63.6	-39.5	-179.4	-174	56.5	0	0	0	111.8	F129 T135 V136 S137 L438 L441 F442 F445	F129-L133 VanDerWaalsContact O-CB 3.22Å; F129-L133 WeakPolarHBondContact O-CB 3.32Å; F129-L133 PolarHBondContact O-N 3.35Å; L133-T135 VanDerWaalsContact C-N 3.34Å; L133-T135 PolarHBondContact O-N 3.02Å; L133-V136 PolarHBondContact O-N 2.94Å; L133-S137 WeakPolarHBondContact O-CB 3.25Å; L133-S137 PolarHBondContact O-N 3.25Å; L133-S137 PolarHBondContact O-OG 3.33Å; L133-L438 HydrophobicContact CD2-CD2 4.2Å; L133-L441 HydrophobicContact CD2-CB 3.72Å; L133-L441 HydrophobicContact CG-CB 3.96Å; L133-F442 HydrophobicContact CD2-CB 4.08Å; L133-F445 HydrophobicContact CD1-CB 4.09Å; L133-F445 HydrophobicContact CD1-CG 4.24Å
134	C	94.8	Very high	88.5	Confident	2 Å²	2	35.2 Å²	35.2	1%	0.014	16%	0.159	C	C	.	.	H	α-helix	trans	-61.7	-41.4	173	-170.3	0	0	0	0	111.7	I116 R130 R131 I132 S137 L138 L435 L441	I116-C134 HydrophobicContact CD1-CB 4.17Å; R130-C134 WeakPolarHBondContact O-CB 3.35Å; R130-C134 PolarHBondContact O-N 3.42Å; R131-C134 PolarHBondContact O-N 2.88Å; I132-C134 VanDerWaalsContact C-N 3.33Å; I132-C134 PolarHBondContact O-N 3.43Å; C134-S137 PolarHBondContact O-N 3.4Å; C134-L138 WeakPolarHBondContact O-CB 3.36Å; C134-L138 VanDerWaalsContact O-CG 3.31Å; C134-L138 WeakPolarHBondContact O-CG 3.41Å; C134-L138 PolarHBondContact O-N 3.47Å; C134-L435 HydrophobicContact CB-CD2 3.87Å; C134-L441 HydrophobicContact CB-CD1 4.47Å; C134-L441 HydrophobicContact CB-CD2 4.17Å
135	T	95.4	Very high	90.3	Very high	1 Å²	1	30 Å²	30	1%	0.006	14%	0.136	C	C	.	.	H	α-helix	trans	-60.5	-50.9	175.7	-57.3	0	0	0	0	110.5	F109 L112 I116 R131 I132 L133 S137 L138 S139	F109-T135 HydrophobicContact CD1-CG2 4.41Å; F109-T135 HydrophobicContact CD2-CG2 4.2Å; F109-T135 HydrophobicContact CE1-CG2 4.29Å; F109-T135 HydrophobicContact CE2-CG2 4.04Å; F109-T135 HydrophobicContact CG-CG2 4.35Å; F109-T135 HydrophobicContact CZ-CG2 4.08Å; F109-T135 WeakPolarHBondContact O-CG2 3.32Å; L112-T135 HydrophobicContact CB-CG2 4.23Å; I116-T135 WeakPolarHBondContact CD1-OG1 3.26Å; R131-T135 WeakPolarHBondContact O-CB 3.2Å; R131-T135 PolarHBondContact O-N 2.84Å; R131-T135 PolarHBondContact O-OG1 3.24Å; I132-T135 WeakPolarHBondContact O-CB 3.24Å; I132-T135 PolarHBondContact O-N 2.93Å; I132-T135 VanDerWaalsContact O-N 3.09Å; L133-T135 VanDerWaalsContact C-N 3.34Å; L133-T135 PolarHBondContact O-N 3.02Å; T135-S137 PolarHBondContact O-N 3.43Å; T135-L138 PolarHBondContact O-N 2.92Å; T135-S139 VanDerWaalsContact O-CB 3.3Å; T135-S139 WeakPolarHBondContact O-CB 3.42Å; T135-S139 PolarHBondContact O-N 3.35Å; T135-S139 PolarHBondContact O-OG 2.91Å
136	V	95.3	Very high	92.2	Very high	23 Å²	23	26 Å²	26	14%	0.139	11%	0.112	C	C	.	.	H	α-helix	trans	-58.3	-48.8	179.3	175.7	0	0	0	0	109.9	L15 F109 I132 L133 S139 T140 F445	L15-V136 HydrophobicContact CD1-CG2 4.25Å; F109-V136 HydrophobicContact CE2-CG2 3.9Å; F109-V136 HydrophobicContact CZ-CG2 4.23Å; I132-V136 WeakPolarHBondContact O-CG2 3.29Å; I132-V136 PolarHBondContact O-N 2.89Å; L133-V136 PolarHBondContact O-N 2.94Å; V136-S139 PolarHBondContact O-N 2.88Å; V136-S139 PolarHBondContact O-OG 2.89Å; V136-T140 PolarHBondContact O-N 3.45Å; V136-T140 VanDerWaalsContact O-N 3.09Å; V136-T140 PolarHBondContact O-OG1 3.21Å; V136-F445 HydrophobicContact CG1-CD2 3.87Å; V136-F445 HydrophobicContact CG1-CE2 3.49Å; V136-F445 VanDerWaalsContact CG1-CE2 3.49Å; V136-F445 HydrophobicContact CG1-CZ 4.29Å
137	S	96.4	Very high	93.8	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-57.1	-52.4	175.4	-59.8	0	0	0	0	112.1	L133 C134 T135 S139 T140 F141 F445 Y448	L133-S137 WeakPolarHBondContact O-CB 3.25Å; L133-S137 PolarHBondContact O-N 3.25Å; L133-S137 PolarHBondContact O-OG 3.33Å; C134-S137 PolarHBondContact O-N 3.4Å; T135-S137 PolarHBondContact O-N 3.43Å; S137-S139 VanDerWaalsContact C-N 3.32Å; S137-S139 PolarHBondContact O-N 3.24Å; S137-T140 CarbonylContact O-C 3.52Å; S137-T140 PolarHBondContact O-N 2.91Å; S137-T140 PolarHBondContact O-OG1 2.96Å; S137-F141 PolarHBondContact O-N 3.32Å; S137-F445 WeakPolarHBondContact OG-CA 3.49Å; S137-F445 WeakPolarHBondContact OG-CB 3.41Å; S137-Y448 WeakPolarHBondContact O-CD2 3.18Å; S137-Y448 WeakPolarHBondContact O-CE2 3.21Å
138	L	97.4	Very high	94.8	Very high	0 Å²	0	15 Å²	15	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-67.6	-31.9	-176.7	-65.2	-174.5	0	0	0	113	L112 I116 C134 T135 T140 F141 Y426 L427 R430 L431	L112-L138 HydrophobicContact CD1-CB 3.89Å; L112-L138 HydrophobicContact CD2-CB 4.34Å; L112-L138 HydrophobicContact CD2-CD1 4.43Å; I116-L138 HydrophobicContact CD1-CD1 4.36Å; C134-L138 WeakPolarHBondContact O-CB 3.36Å; C134-L138 VanDerWaalsContact O-CG 3.31Å; C134-L138 WeakPolarHBondContact O-CG 3.41Å; C134-L138 PolarHBondContact O-N 3.47Å; T135-L138 PolarHBondContact O-N 2.92Å; L138-T140 VanDerWaalsContact C-N 3.3Å; L138-F141 VanDerWaalsContact O-CB 3.24Å; L138-F141 WeakPolarHBondContact O-CB 3.45Å; L138-F141 PolarHBondContact O-N 3.06Å; L138-Y426 HydrophobicContact CD2-CE1 4.49Å; L138-L427 HydrophobicContact CB-CD2 4.24Å; L138-L427 HydrophobicContact CD2-CD2 4.39Å; L138-R430 HydrophobicContact CD1-CB 3.98Å; L138-R430 HydrophobicContact CD2-CB 3.64Å; L138-R430 HydrophobicContact CD2-CG 3.83Å; L138-R430 HydrophobicContact CG-CB 4.48Å; L138-L431 HydrophobicContact CD1-CD2 4.36Å
139	S	96.7	Very high	95.5	Very high	1 Å²	1	14.3 Å²	14.3	1%	0.007	7%	0.066	C	C	.	.	H	α-helix	trans	-69.4	-28.7	175	70.7	0	0	0	0	113	F109 T135 V136 S137 F141	F109-S139 VanDerWaalsContact CD2-OG 3.29Å; F109-S139 WeakPolarHBondContact CD2-OG 3.44Å; T135-S139 VanDerWaalsContact O-CB 3.3Å; T135-S139 WeakPolarHBondContact O-CB 3.42Å; T135-S139 PolarHBondContact O-N 3.35Å; T135-S139 PolarHBondContact O-OG 2.91Å; V136-S139 PolarHBondContact O-N 2.88Å; V136-S139 PolarHBondContact O-OG 2.89Å; S137-S139 VanDerWaalsContact C-N 3.32Å; S137-S139 PolarHBondContact O-N 3.24Å; S139-F141 VanDerWaalsContact C-N 3.33Å
140	T	97.2	Very high	96	Very high	15 Å²	15	8.9 Å²	8.9	9%	0.092	4%	0.042	C	C	.	.	T	Hydrogen-bonded Turn	trans	-98.5	22.4	174.9	61.4	0	0	0	0	111.8	V136 S137 L138 Y145 N452	V136-T140 PolarHBondContact O-N 3.45Å; V136-T140 VanDerWaalsContact O-N 3.09Å; V136-T140 PolarHBondContact O-OG1 3.21Å; S137-T140 CarbonylContact O-C 3.52Å; S137-T140 PolarHBondContact O-N 2.91Å; S137-T140 PolarHBondContact O-OG1 2.96Å; L138-T140 VanDerWaalsContact C-N 3.3Å; T140-Y145 HydrophobicContact CG2-CD2 4.42Å; T140-Y145 HydrophobicContact CG2-CE2 4.3Å; T140-N452 PolarHBondContact O-ND2 3.48Å
141	F	98.4	Very high	96.4	Very high	0 Å²	0	6 Å²	6	0%	0	3%	0.031	C	C	.	.			trans	-54.2	121.3	177.6	173.4	-123.4	0	0	0	110.7	S137 L138 S139 V143 L144 Y145 F301 F305 I423 Y426 L427 Y448	S137-F141 PolarHBondContact O-N 3.32Å; L138-F141 VanDerWaalsContact O-CB 3.24Å; L138-F141 WeakPolarHBondContact O-CB 3.45Å; L138-F141 PolarHBondContact O-N 3.06Å; S139-F141 VanDerWaalsContact C-N 3.33Å; F141-V143 HydrophobicContact CE1-CB 3.94Å; F141-V143 HydrophobicContact CE1-CG2 4.27Å; F141-V143 HydrophobicContact CZ-CB 4.27Å; F141-V143 HydrophobicContact CZ-CG2 4.09Å; F141-V143 PolarHBondContact O-N 2.69Å; F141-V143 VanDerWaalsContact O-N 3.16Å; F141-L144 HydrophobicContact CD1-CB 3.97Å; F141-L144 PolarHBondContact O-N 2.89Å; F141-L144 VanDerWaalsContact O-N 3.14Å; F141-Y145 WeakPolarHBondContact O-CB 3.3Å; F141-Y145 PolarHBondContact O-N 3.47Å; F141-F301 HydrophobicContact CE1-CZ 4.36Å; F141-F301 HydrophobicContact CE2-CZ 4.48Å; F141-F301 AromaticContact CZ-CE1 3.81Å; F141-F301 HydrophobicContact CZ-CE1 3.81Å; F141-F301 AromaticContact CZ-CZ 3.57Å; F141-F301 HydrophobicContact CZ-CZ 3.57Å; F141-F305 HydrophobicContact CE2-CB 4.04Å; F141-F305 AromaticContact CE2-CD1 3.9Å; F141-F305 HydrophobicContact CE2-CD1 3.9Å; F141-F305 HydrophobicContact CE2-CD2 4.13Å; F141-F305 HydrophobicContact CE2-CE1 4.4Å; F141-F305 AromaticContact CE2-CG 3.75Å; F141-F305 HydrophobicContact CE2-CG 3.75Å; F141-F305 HydrophobicContact CZ-CD2 4.46Å; F141-I423 HydrophobicContact CE1-CG1 4.17Å; F141-Y426 HydrophobicContact CD1-CD1 4.33Å; F141-Y426 AromaticContact CD2-CD1 3.89Å; F141-Y426 HydrophobicContact CD2-CD1 3.89Å; F141-Y426 AromaticContact CD2-CE1 3.69Å; F141-Y426 HydrophobicContact CD2-CE1 3.69Å; F141-Y426 HydrophobicContact CE1-CD1 4.01Å; F141-Y426 AromaticContact CE2-CD1 3.55Å; F141-Y426 HydrophobicContact CE2-CD1 3.55Å; F141-Y426 AromaticContact CE2-CE1 3.57Å; F141-Y426 HydrophobicContact CE2-CE1 3.57Å; F141-Y426 HydrophobicContact CE2-CG 4.25Å; F141-Y426 HydrophobicContact CG-CD1 4.27Å; F141-Y426 HydrophobicContact CG-CE1 4.35Å; F141-Y426 AromaticContact CZ-CD1 3.59Å; F141-Y426 HydrophobicContact CZ-CD1 3.59Å; F141-Y426 HydrophobicContact CZ-CE1 4.11Å; F141-Y426 HydrophobicContact CZ-CG 4.02Å; F141-L427 HydrophobicContact CB-CD2 4.44Å; F141-Y448 HydrophobicContact CB-CE2 4.31Å; F141-Y448 HydrophobicContact CD2-CE1 4.36Å; F141-Y448 HydrophobicContact CD2-CE2 4.01Å; F141-Y448 AromaticContact CD2-CZ 3.8Å
142	P	98.4	Very high	96.7	Very high	0 Å²	0	5 Å²	5	0%	0	3%	0.028	C	C	.	.	H	α-helix	trans	-62.3	-36.7	-156.5	-30.8	37.5	0	0	0	116.8	F146 F305 Y448 V451 N452 W477	P142-F146 PolarHBondContact O-N 3.19Å; P142-F305 HydrophobicContact CB-CE1 4.15Å; P142-F305 HydrophobicContact CG-CD1 4.36Å; P142-F305 HydrophobicContact CG-CE1 3.9Å; P142-Y448 HydrophobicContact CG-CD1 3.88Å; P142-Y448 HydrophobicContact CG-CG 3.86Å; P142-V451 HydrophobicContact CB-CB 4.04Å; P142-V451 HydrophobicContact CB-CG1 3.56Å; P142-V451 HydrophobicContact CG-CB 3.91Å; P142-V451 HydrophobicContact CG-CG1 3.95Å; P142-N452 WeakPolarHBondContact CA-OD1 3.34Å; P142-W477 HydrophobicContact CB-CZ2 4.1Å; P142-W477 PolarHBondContact O-NE1 2.89Å
143	V	98	Very high	97	Very high	0 Å²	0	4.5 Å²	4.5	0%	0	3%	0.025	C	C	.	.	H	α-helix	trans	-65.8	-51.5	178.7	-174.8	0	0	0	0	109.7	F141 F147 F301 F305 F419 R420 I423 W477	F141-V143 HydrophobicContact CE1-CB 3.94Å; F141-V143 HydrophobicContact CE1-CG2 4.27Å; F141-V143 HydrophobicContact CZ-CB 4.27Å; F141-V143 HydrophobicContact CZ-CG2 4.09Å; F141-V143 PolarHBondContact O-N 2.69Å; F141-V143 VanDerWaalsContact O-N 3.16Å; V143-F147 HydrophobicContact CG1-CD2 4.48Å; V143-F147 HydrophobicContact CG1-CE2 4.31Å; V143-F147 WeakPolarHBondContact O-CD2 3.28Å; V143-F301 HydrophobicContact CG2-CE2 3.96Å; V143-F301 HydrophobicContact CG2-CZ 3.91Å; V143-F305 HydrophobicContact CG2-CE2 4.44Å; V143-F305 HydrophobicContact CG2-CZ 4.26Å; V143-F419 HydrophobicContact CG1-CB 4.27Å; V143-F419 HydrophobicContact CG2-CB 4.29Å; V143-R420 HydrophobicContact CG1-CG 4.24Å; V143-I423 HydrophobicContact CB-CG1 4.31Å; V143-I423 HydrophobicContact CG1-CD1 4.04Å; V143-I423 HydrophobicContact CG1-CG1 3.99Å; V143-W477 HydrophobicContact CG1-CD2 4.5Å; V143-W477 HydrophobicContact CG1-CG 4.39Å; V143-W477 HydrophobicContact CG2-CD2 4.07Å; V143-W477 HydrophobicContact CG2-CE3 4.11Å; V143-W477 HydrophobicContact CG2-CH2 4.3Å; V143-W477 HydrophobicContact CG2-CZ2 4.21Å; V143-W477 HydrophobicContact CG2-CZ3 4.25Å
144	L	98.3	Very high	97.2	Very high	4 Å²	4	3.1 Å²	3.1	2%	0.021	2%	0.018	C	C	.	.	H	α-helix	trans	-65.4	-43.1	180	178.9	59.4	0	0	0	112	F141 F146 F147 T148 D154 T158 I423 L427	F141-L144 HydrophobicContact CD1-CB 3.97Å; F141-L144 PolarHBondContact O-N 2.89Å; F141-L144 VanDerWaalsContact O-N 3.14Å; L144-F146 VanDerWaalsContact C-N 3.27Å; L144-F146 PolarHBondContact O-N 2.95Å; L144-F147 PolarHBondContact O-N 3.42Å; L144-F147 VanDerWaalsContact O-N 3.12Å; L144-T148 PolarHBondContact O-N 3.36Å; L144-T148 VanDerWaalsContact O-N 3.09Å; L144-T148 PolarHBondContact O-OG1 3.04Å; L144-D154 HydrophobicContact CD1-CB 4.22Å; L144-T158 HydrophobicContact CD2-CG2 3.83Å; L144-I423 HydrophobicContact CB-CD1 4.25Å; L144-I423 HydrophobicContact CB-CG1 4.45Å; L144-I423 HydrophobicContact CB-CG2 4Å; L144-I423 HydrophobicContact CD1-CD1 4.29Å; L144-I423 HydrophobicContact CD1-CG2 4.23Å; L144-I423 HydrophobicContact CD2-CG2 4.08Å; L144-I423 HydrophobicContact CG-CG2 4.34Å; L144-L427 HydrophobicContact CD2-CD1 4.05Å
145	Y	98.2	Very high	97.4	Very high	9 Å²	9	3 Å²	3	4%	0.035	2%	0.017	C	C	.	.	H	α-helix	trans	-63.1	-34.1	-175.6	-166	-111.6	0	0	0	112.3	S23 L26 T140 F141 T148 F149	S23-Y145 PolarHBondContact OG-OH 2.89Å; L26-Y145 HydrophobicContact CD1-CE1 3.85Å; T140-Y145 HydrophobicContact CG2-CD2 4.42Å; T140-Y145 HydrophobicContact CG2-CE2 4.3Å; F141-Y145 WeakPolarHBondContact O-CB 3.3Å; F141-Y145 PolarHBondContact O-N 3.47Å; Y145-T148 VanDerWaalsContact O-CB 3.24Å; Y145-T148 WeakPolarHBondContact O-CB 3.42Å; Y145-T148 PolarHBondContact O-N 2.86Å; Y145-F149 AromaticContact CD1-CE2 3.93Å; Y145-F149 HydrophobicContact CD1-CE2 3.93Å; Y145-F149 HydrophobicContact CD1-CZ 4.16Å; Y145-F149 AromaticContact CE1-CE2 3.77Å; Y145-F149 HydrophobicContact CE1-CE2 3.77Å; Y145-F149 AromaticContact CE1-CZ 3.6Å; Y145-F149 HydrophobicContact CE1-CZ 3.6Å; Y145-F149 HydrophobicContact CE2-CZ 4.18Å; Y145-F149 AromaticContact CZ-CZ 3.6Å; Y145-F149 WeakPolarHBondContact O-CD2 3.22Å; Y145-F149 WeakPolarHBondContact O-CE2 3.32Å
146	F	98.2	Very high	97.5	Very high	0 Å²	0	3 Å²	3	0%	0	2%	0.017	C	C	.	.	H	α-helix	trans	-64.5	-44.9	173.2	-174.8	-84.9	0	0	0	112.6	M30 P142 L144 T148 F149 L150 I456 F459 M476 W477	M30-F146 HydrophobicContact CE-CE2 4.23Å; M30-F146 HydrophobicContact CE-CZ 4.29Å; P142-F146 PolarHBondContact O-N 3.19Å; L144-F146 VanDerWaalsContact C-N 3.27Å; L144-F146 PolarHBondContact O-N 2.95Å; F146-T148 PolarHBondContact O-N 2.71Å; F146-F149 PolarHBondContact O-N 3.36Å; F146-L150 HydrophobicContact CD1-CD1 4.43Å; F146-L150 HydrophobicContact CE1-CD1 3.83Å; F146-I456 HydrophobicContact CD2-CG1 4.33Å; F146-F459 HydrophobicContact CE2-CB 3.84Å; F146-F459 HydrophobicContact CE2-CD2 4.35Å; F146-F459 HydrophobicContact CE2-CG 4.19Å; F146-F459 HydrophobicContact CZ-CB 3.97Å; F146-F459 AromaticContact CZ-CD2 3.61Å; F146-F459 HydrophobicContact CZ-CD2 3.61Å; F146-F459 HydrophobicContact CZ-CE2 4.28Å; F146-F459 AromaticContact CZ-CG 3.9Å; F146-F459 HydrophobicContact CZ-CG 3.9Å; F146-M476 HydrophobicContact CE1-CB 3.49Å; F146-M476 VanDerWaalsContact CE1-CB 3.49Å; F146-M476 HydrophobicContact CZ-CB 3.5Å; F146-W477 AromaticContact CD1-CD1 3.88Å; F146-W477 AromaticContact CD2-CD1 3.92Å; F146-W477 AromaticContact CG-CD1 3.45Å; F146-W477 VanDerWaalsContact CG-CD1 3.45Å
147	F	97.3	Very high	97.6	Very high	0 Å²	0	2 Å²	2	0%	0	1%	0.011	C	C	.	.	H	α-helix	trans	-71.6	-12.8	178.6	-72.5	-71.7	0	0	0	113.8	V143 L144 F149 L150 Y152 D154 R420 M476 W477	V143-F147 HydrophobicContact CG1-CD2 4.48Å; V143-F147 HydrophobicContact CG1-CE2 4.31Å; V143-F147 WeakPolarHBondContact O-CD2 3.28Å; L144-F147 PolarHBondContact O-N 3.42Å; L144-F147 VanDerWaalsContact O-N 3.12Å; F147-F149 PolarHBondContact O-N 3.36Å; F147-L150 PolarHBondContact O-N 3.25Å; F147-Y152 AromaticContact CD1-CD1 3.59Å; F147-Y152 HydrophobicContact CD1-CD1 3.59Å; F147-Y152 HydrophobicContact CD1-CD2 4.19Å; F147-Y152 HydrophobicContact CD1-CE1 4.14Å; F147-Y152 AromaticContact CD1-CG 3.66Å; F147-Y152 HydrophobicContact CD1-CG 3.66Å; F147-Y152 AromaticContact CE1-CD1 3.69Å; F147-Y152 HydrophobicContact CE1-CD1 3.69Å; F147-Y152 AromaticContact CE1-CE1 3.78Å; F147-Y152 HydrophobicContact CE1-CE1 3.78Å; F147-Y152 HydrophobicContact CE1-CG 4.16Å; F147-D154 HydrophobicContact CB-CB 4.33Å; F147-R420 HydrophobicContact CD2-CG 3.84Å; F147-R420 VanDerWaalsContact CE2-CD 3.4Å; F147-R420 HydrophobicContact CE2-CG 3.25Å; F147-R420 HydrophobicContact CZ-CG 3.74Å; F147-M476 HydrophobicContact CE1-CE 3.37Å; F147-M476 HydrophobicContact CZ-CE 3.65Å; F147-W477 HydrophobicContact CE2-CB 3.49Å; F147-W477 VanDerWaalsContact CE2-CB 3.49Å; F147-W477 HydrophobicContact CE2-CG 4.37Å; F147-W477 HydrophobicContact CZ-CB 3.79Å
148	T	97.1	Very high	97.8	Very high	0 Å²	0	2.1 Å²	2.1	0%	0	1%	0.012	C	C	.	.	T	Hydrogen-bonded Turn	trans	-57.8	-27.6	167.9	-65.1	0	0	0	0	112.3	N101 V102 N105 L144 Y145 F146	N101-T148 VanDerWaalsContact CB-O 3.24Å; N101-T148 WeakPolarHBondContact CB-O 3.41Å; V102-T148 HydrophobicContact CG2-CG2 4.33Å; N105-T148 HydrophobicContact CB-CG2 3.41Å; N105-T148 VanDerWaalsContact CB-CG2 3.41Å; L144-T148 PolarHBondContact O-N 3.36Å; L144-T148 VanDerWaalsContact O-N 3.09Å; L144-T148 PolarHBondContact O-OG1 3.04Å; Y145-T148 VanDerWaalsContact O-CB 3.24Å; Y145-T148 WeakPolarHBondContact O-CB 3.42Å; Y145-T148 PolarHBondContact O-N 2.86Å; F146-T148 PolarHBondContact O-N 2.71Å
149	F	97.8	Very high	97.8	Very high	0 Å²	0	4 Å²	4	0%	0	2%	0.02	C	C	.	.	T	Hydrogen-bonded Turn	trans	-96	-3.8	-175.1	-52	-56.5	0	0	0	114.5	S23 L26 F27 M30 R98 Y145 F146 F147 I456	S23-F149 VanDerWaalsContact O-CE1 3.3Å; S23-F149 WeakPolarHBondContact O-CE1 3.05Å; L26-F149 HydrophobicContact CB-CE1 3.93Å; L26-F149 HydrophobicContact CB-CE2 4.27Å; L26-F149 HydrophobicContact CB-CZ 3.71Å; L26-F149 HydrophobicContact CD1-CE2 4.37Å; L26-F149 HydrophobicContact CD1-CZ 3.92Å; L26-F149 HydrophobicContact CG-CZ 4.49Å; F27-F149 HydrophobicContact CB-CD1 3.84Å; F27-F149 HydrophobicContact CB-CE1 4.26Å; M30-F149 HydrophobicContact CE-CB 3.97Å; M30-F149 HydrophobicContact CE-CD2 4.33Å; M30-F149 HydrophobicContact SD-CB 3.54Å; M30-F149 VanDerWaalsContact SD-CB 3.54Å; M30-F149 HydrophobicContact SD-CD2 3.37Å; M30-F149 WeakPolarHBondContact SD-CD2 3.4Å; M30-F149 HydrophobicContact SD-CE2 4.25Å; M30-F149 HydrophobicContact SD-CG 3.63Å; R98-F149 WeakPolarHBondContact CD-O 3.25Å; Y145-F149 AromaticContact CD1-CE2 3.93Å; Y145-F149 HydrophobicContact CD1-CE2 3.93Å; Y145-F149 HydrophobicContact CD1-CZ 4.16Å; Y145-F149 AromaticContact CE1-CE2 3.77Å; Y145-F149 HydrophobicContact CE1-CE2 3.77Å; Y145-F149 AromaticContact CE1-CZ 3.6Å; Y145-F149 HydrophobicContact CE1-CZ 3.6Å; Y145-F149 HydrophobicContact CE2-CZ 4.18Å; Y145-F149 AromaticContact CZ-CZ 3.6Å; Y145-F149 WeakPolarHBondContact O-CD2 3.22Å; Y145-F149 WeakPolarHBondContact O-CE2 3.32Å; F146-F149 PolarHBondContact O-N 3.36Å; F147-F149 PolarHBondContact O-N 3.36Å; F149-I456 HydrophobicContact CE2-CD1 3.98Å
150	L	97.2	Very high	97.9	Very high	2 Å²	2	5 Å²	5	1%	0.01	2%	0.024	C	C	.	.	T	Hydrogen-bonded Turn	trans	-119	160.3	177.1	-62	175.1	0	0	0	109.8	N101 F146 F147 Y152 F459 M476	N101-L150 PolarHBondContact ND2-O 3.46Å; F146-L150 HydrophobicContact CD1-CD1 4.43Å; F146-L150 HydrophobicContact CE1-CD1 3.83Å; F147-L150 PolarHBondContact O-N 3.25Å; L150-Y152 VanDerWaalsContact C-N 3.3Å; L150-Y152 HydrophobicContact CB-CD2 3.61Å; L150-Y152 HydrophobicContact CB-CE2 4.09Å; L150-Y152 HydrophobicContact CD1-CE2 4.34Å; L150-Y152 PolarHBondContact O-N 3.15Å; L150-F459 HydrophobicContact CD2-CZ 4.29Å; L150-M476 HydrophobicContact CD1-CE 4.36Å
151	Y	97.6	Very high	98	Very high	0 Å²	0	4.3 Å²	4.3	0%	0	2%	0.02	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.9	72.4	-176.1	-167.6	-120.3	0	0	0	111.8	E41 H44 V45 A48 L69 Y70 S73 L97	E41-Y151 VanDerWaalsContact OE1-CB 3.23Å; E41-Y151 WeakPolarHBondContact OE1-CB 3.5Å; E41-Y151 PolarHBondContact OE1-N 3.42Å; H44-Y151 HydrophobicContact CB-CD1 3.93Å; H44-Y151 HydrophobicContact CB-CE1 4.24Å; V45-Y151 HydrophobicContact CG2-CD1 3.94Å; V45-Y151 HydrophobicContact CG2-CG 4.46Å; A48-Y151 HydrophobicContact CB-CE1 3.83Å; L69-Y151 HydrophobicContact CD1-CD2 4.27Å; L69-Y151 HydrophobicContact CD1-CE2 3.69Å; L69-Y151 HydrophobicContact CD2-CD1 4.1Å; L69-Y151 HydrophobicContact CD2-CD2 4.45Å; L69-Y151 HydrophobicContact CD2-CE1 3.82Å; L69-Y151 HydrophobicContact CD2-CE2 4.19Å; L69-Y151 HydrophobicContact CD2-CG 4.42Å; L69-Y151 HydrophobicContact CG-CE1 4.05Å; L69-Y151 HydrophobicContact CG-CE2 3.9Å; L69-Y151 PolarHBondContact O-OH 3.11Å; Y70-Y151 HydrophobicContact CD1-CE1 4.1Å; Y70-Y151 HydrophobicContact CE1-CE1 4.15Å; S73-Y151 WeakPolarHBondContact CB-OH 3.21Å; S73-Y151 VanDerWaalsContact OG-CE2 3.24Å; S73-Y151 WeakPolarHBondContact OG-CE2 3.27Å; S73-Y151 PolarHBondContact OG-OH 3.22Å; L97-Y151 HydrophobicContact CB-CD1 4.29Å; L97-Y151 HydrophobicContact CB-CD2 3.7Å; L97-Y151 HydrophobicContact CB-CE1 4.29Å; L97-Y151 HydrophobicContact CB-CE2 3.69Å; L97-Y151 HydrophobicContact CB-CG 4Å; L97-Y151 HydrophobicContact CD1-CE1 4.4Å; L97-Y151 HydrophobicContact CD2-CE1 4.47Å; L97-Y151 HydrophobicContact CD2-CE2 4.22Å; L97-Y151 WeakPolarHBondContact O-CD2 3.45Å; L97-Y151 VanDerWaalsContact O-CE2 3.3Å; L97-Y151 WeakPolarHBondContact O-CE2 3.14Å
152	Y	97.1	Very high	98	Very high	1 Å²	1	4.4 Å²	4.4	0%	0.004	2%	0.021	C	C	.	.			trans	-121.3	158	-171.9	-89.2	-110.3	0	0	0	111.7	M39 D40 E41 N101 F147 L150 D154 R420	M39-Y152 VanDerWaalsContact CB-OH 3.26Å; M39-Y152 WeakPolarHBondContact CB-OH 3.48Å; D40-Y152 HydrophobicContact CB-CE1 4.16Å; D40-Y152 WeakPolarHBondContact CB-OH 3.19Å; D40-Y152 VanDerWaalsContact CG-OH 3.27Å; D40-Y152 PolarHBondContact N-OH 2.9Å; D40-Y152 VanDerWaalsContact OD2-CE1 3.24Å; D40-Y152 WeakPolarHBondContact OD2-CE1 3.38Å; D40-Y152 PolarHBondContact OD2-OH 3.46Å; E41-Y152 HydrophobicContact CG-CD2 4.15Å; E41-Y152 HydrophobicContact CG-CE2 3.86Å; N101-Y152 PolarHBondContact ND2-N 3.16Å; N101-Y152 VanDerWaalsContact ND2-N 3.2Å; N101-Y152 PolarHBondContact ND2-O 3.07Å; F147-Y152 AromaticContact CD1-CD1 3.59Å; F147-Y152 HydrophobicContact CD1-CD1 3.59Å; F147-Y152 HydrophobicContact CD1-CD2 4.19Å; F147-Y152 HydrophobicContact CD1-CE1 4.14Å; F147-Y152 AromaticContact CD1-CG 3.66Å; F147-Y152 HydrophobicContact CD1-CG 3.66Å; F147-Y152 AromaticContact CE1-CD1 3.69Å; F147-Y152 HydrophobicContact CE1-CD1 3.69Å; F147-Y152 AromaticContact CE1-CE1 3.78Å; F147-Y152 HydrophobicContact CE1-CE1 3.78Å; F147-Y152 HydrophobicContact CE1-CG 4.16Å; L150-Y152 VanDerWaalsContact C-N 3.3Å; L150-Y152 HydrophobicContact CB-CD2 3.61Å; L150-Y152 HydrophobicContact CB-CE2 4.09Å; L150-Y152 HydrophobicContact CD1-CE2 4.34Å; L150-Y152 PolarHBondContact O-N 3.15Å; Y152-D154 VanDerWaalsContact C-N 3.31Å; Y152-D154 PolarHBondContact O-N 3.24Å; Y152-R420 VanDerWaalsContact CD1-CZ 3.45Å
153	T	97.4	Very high	98	Very high	3 Å²	3	7.5 Å²	7.5	2%	0.018	3%	0.034	C	C	.	.	S	Bend	trans	-76.2	-15.4	-176.1	57.9	0	0	0	0	113.9	T65 L69 A155 S157 F186	T65-T153 HydrophobicContact CG2-CG2 4.16Å; L69-T153 HydrophobicContact CB-CG2 4.09Å; L69-T153 HydrophobicContact CD2-CG2 3.97Å; T153-A155 PolarHBondContact O-N 3.25Å; T153-S157 WeakPolarHBondContact O-CB 3.37Å; T153-S157 PolarHBondContact O-N 2.95Å; T153-F186 WeakPolarHBondContact O-CD1 3.39Å
154	D	97.9	Very high	98.1	Very high	4 Å²	4	7.6 Å²	7.6	2%	0.021	4%	0.035	C	C	.	.	H	α-helix	trans	-63.1	-41.4	-169	-57.1	-84.9	0	0	0	114.2	L144 F147 Y152 T158 R187 R420 I423	L144-D154 HydrophobicContact CD1-CB 4.22Å; F147-D154 HydrophobicContact CB-CB 4.33Å; Y152-D154 VanDerWaalsContact C-N 3.31Å; Y152-D154 PolarHBondContact O-N 3.24Å; D154-T158 WeakPolarHBondContact O-CB 3.36Å; D154-T158 PolarHBondContact O-N 3.01Å; D154-T158 PolarHBondContact O-OG1 3.29Å; D154-R187 IonicContact OD1-CZ 2.69Å; D154-R187 IonicContact OD1-NH1 2.94Å; D154-R187 PolarHBondContact OD1-NH1 2.92Å; D154-R187 IonicContact OD2-NH1 2.66Å; D154-R420 IonicContact OD1-CZ 3.41Å; D154-R420 IonicContact OD1-NE 2.72Å; D154-R420 PolarHBondContact OD1-NE 2.81Å; D154-R420 IonicContact OD1-NH2 3.94Å; D154-R420 IonicContact OD2-CZ 3.61Å; D154-R420 VanDerWaalsContact OD2-CZ 3.27Å; D154-R420 IonicContact OD2-NE 3.77Å; D154-R420 PolarHBondContact OD2-NE 3.09Å; D154-R420 IonicContact OD2-NH2 3.69Å; D154-R420 PolarHBondContact OD2-NH2 3.03Å; D154-I423 HydrophobicContact CB-CD1 4.1Å
155	A	97.8	Very high	98.1	Very high	0 Å²	0	7.6 Å²	7.6	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-65.2	-50	-177.9	0	0	0	0	0	112.1	N101 F104 N108 T153 T158 F159	N101-A155 HydrophobicContact CB-CB 3.96Å; F104-A155 HydrophobicContact CB-CB 3.97Å; N108-A155 PolarHBondContact ND2-O 2.98Å; T153-A155 PolarHBondContact O-N 3.25Å; A155-T158 PolarHBondContact O-N 3.26Å; A155-F159 PolarHBondContact O-N 3.11Å
156	G	98.1	Very high	98.1	Very high	0 Å²	0	7.4 Å²	7.4	0%	0	3%	0.034	C	C	.	.	H	α-helix	trans	-70.1	-39.1	177.2	0	0	0	0	0	112.9	T158 F159 F160	G156-T158 VanDerWaalsContact C-N 3.31Å; G156-T158 PolarHBondContact O-N 2.95Å; G156-F159 WeakPolarHBondContact O-CB 3.4Å; G156-F159 PolarHBondContact O-N 2.67Å; G156-F160 VanDerWaalsContact O-CD2 3.25Å; G156-F160 WeakPolarHBondContact O-CD2 3.46Å; G156-F160 PolarHBondContact O-N 3.07Å
157	S	98.1	Very high	98.1	Very high	3 Å²	3	9 Å²	9	2%	0.021	4%	0.042	C	C	.	.	H	α-helix	trans	-53	-49	171.7	174.3	0	0	0	0	111.6	T153 I161 N190	T153-S157 WeakPolarHBondContact O-CB 3.37Å; T153-S157 PolarHBondContact O-N 2.95Å; S157-I161 WeakPolarHBondContact O-CG1 3.48Å; S157-I161 PolarHBondContact O-N 3.49Å; S157-N190 PolarHBondContact OG-ND2 2.76Å; S157-N190 PolarHBondContact OG-OD1 3.27Å
158	T	98.7	Very high	98.2	Very high	3 Å²	3	9.3 Å²	9.3	2%	0.018	4%	0.044	C	C	.	.	H	α-helix	trans	-63.5	-45.5	177.6	-58	0	0	0	0	111.2	L144 D154 A155 G156 F160 I161 L162 L427	L144-T158 HydrophobicContact CD2-CG2 3.83Å; D154-T158 WeakPolarHBondContact O-CB 3.36Å; D154-T158 PolarHBondContact O-N 3.01Å; D154-T158 PolarHBondContact O-OG1 3.29Å; A155-T158 PolarHBondContact O-N 3.26Å; G156-T158 VanDerWaalsContact C-N 3.31Å; G156-T158 PolarHBondContact O-N 2.95Å; T158-F160 PolarHBondContact O-N 2.94Å; T158-I161 PolarHBondContact O-N 3.24Å; T158-L162 HydrophobicContact CG2-CD1 3.73Å; T158-L162 HydrophobicContact CG2-CG 4.05Å; T158-L162 WeakPolarHBondContact O-CB 3.42Å; T158-L162 VanDerWaalsContact O-CG 3.28Å; T158-L162 WeakPolarHBondContact O-CG 3.36Å; T158-L162 PolarHBondContact O-N 3.31Å; T158-L427 HydrophobicContact CG2-CD1 3.5Å
159	F	98.8	Very high	98.1	Very high	38 Å²	38	11.6 Å²	11.6	17%	0.167	6%	0.056	C	C	.	.	H	α-helix	trans	-56.1	-53.4	180	175.2	-93.7	0	0	0	112.5	F104 N108 L111 A155 G156 I161 L162 F163	F104-F159 HydrophobicContact CD1-CB 3.75Å; F104-F159 AromaticContact CD1-CD1 3.86Å; F104-F159 HydrophobicContact CD1-CD1 3.86Å; F104-F159 HydrophobicContact CD1-CD2 4.32Å; F104-F159 AromaticContact CD1-CG 3.71Å; F104-F159 HydrophobicContact CD1-CG 3.71Å; F104-F159 HydrophobicContact CE1-CB 4.39Å; F104-F159 AromaticContact CE1-CD1 3.89Å; F104-F159 HydrophobicContact CE1-CD1 3.89Å; F104-F159 HydrophobicContact CE1-CE1 4.5Å; F104-F159 HydrophobicContact CE1-CG 4.22Å; F104-F159 HydrophobicContact CG-CB 4.46Å; N108-F159 WeakPolarHBondContact OD1-CA 3.37Å; N108-F159 VanDerWaalsContact OD1-CB 3.32Å; N108-F159 WeakPolarHBondContact OD1-CB 3.43Å; N108-F159 PolarHBondContact OD1-N 3.15Å; N108-F159 VanDerWaalsContact OD1-N 3.1Å; L111-F159 HydrophobicContact CD1-CD2 3.44Å; L111-F159 VanDerWaalsContact CD1-CD2 3.44Å; L111-F159 HydrophobicContact CD1-CE2 3.45Å; L111-F159 VanDerWaalsContact CD1-CE2 3.45Å; L111-F159 HydrophobicContact CD1-CG 4.14Å; L111-F159 HydrophobicContact CD1-CZ 4.16Å; L111-F159 WeakPolarHBondContact CD1-O 3.42Å; L111-F159 HydrophobicContact CG-CE2 4.25Å; A155-F159 PolarHBondContact O-N 3.11Å; G156-F159 WeakPolarHBondContact O-CB 3.4Å; G156-F159 PolarHBondContact O-N 2.67Å; F159-I161 VanDerWaalsContact C-N 3.35Å; F159-I161 PolarHBondContact O-N 2.86Å; F159-L162 PolarHBondContact O-N 3.07Å; F159-F163 HydrophobicContact CE1-CD1 4.11Å; F159-F163 HydrophobicContact CZ-CD1 4.09Å; F159-F163 WeakPolarHBondContact O-CB 3.28Å; F159-F163 PolarHBondContact O-N 2.76Å
160	F	98.8	Very high	98.1	Very high	22 Å²	22	17.2 Å²	17.2	10%	0.096	8%	0.078	C	C	.	.	H	α-helix	trans	-67.1	-34.7	-177.5	-74.9	-67.8	0	0	0	112.6	V72 F104 G156 T158 A164 L179 C182 A183 F186	V72-F160 HydrophobicContact CG2-CE2 4.3Å; V72-F160 HydrophobicContact CG2-CZ 4.32Å; F104-F160 AromaticContact CE1-CE2 3.91Å; F104-F160 HydrophobicContact CE1-CE2 3.91Å; F104-F160 HydrophobicContact CE1-CZ 4.39Å; F104-F160 HydrophobicContact CZ-CE2 4.09Å; G156-F160 VanDerWaalsContact O-CD2 3.25Å; G156-F160 WeakPolarHBondContact O-CD2 3.46Å; G156-F160 PolarHBondContact O-N 3.07Å; T158-F160 PolarHBondContact O-N 2.94Å; F160-A164 WeakPolarHBondContact O-CB 3.36Å; F160-A164 PolarHBondContact O-N 3.36Å; F160-L179 HydrophobicContact CD1-CD2 3.85Å; F160-L179 HydrophobicContact CE1-CD2 4.19Å; F160-C182 HydrophobicContact CB-CB 4.37Å; F160-C182 HydrophobicContact CD1-CB 3.46Å; F160-C182 VanDerWaalsContact CD1-CB 3.46Å; F160-C182 HydrophobicContact CD2-CB 4.12Å; F160-C182 HydrophobicContact CE1-CB 3.65Å; F160-C182 HydrophobicContact CE2-CB 4.29Å; F160-C182 HydrophobicContact CG-CB 3.72Å; F160-C182 HydrophobicContact CZ-CB 4.07Å; F160-A183 HydrophobicContact CB-CB 3.72Å; F160-F186 AromaticContact CD2-CD2 3.95Å; F160-F186 HydrophobicContact CD2-CD2 3.95Å; F160-F186 AromaticContact CD2-CE2 3.78Å; F160-F186 HydrophobicContact CD2-CE2 3.78Å; F160-F186 HydrophobicContact CD2-CZ 4.48Å; F160-F186 HydrophobicContact CE2-CD2 4.09Å; F160-F186 AromaticContact CE2-CE2 3.45Å; F160-F186 HydrophobicContact CE2-CE2 3.45Å; F160-F186 VanDerWaalsContact CE2-CE2 3.45Å; F160-F186 HydrophobicContact CE2-CZ 4.03Å
161	I	98.8	Very high	98.1	Very high	2 Å²	2	19.1 Å²	19.1	1%	0.01	10%	0.098	C	C	.	.	H	α-helix	trans	-68.7	-44.5	174.3	-72.6	-55.7	0	0	0	112.3	S157 T158 F159 F163 A164 Y165 A183 N190 W193 I424 M428	S157-I161 WeakPolarHBondContact O-CG1 3.48Å; S157-I161 PolarHBondContact O-N 3.49Å; T158-I161 PolarHBondContact O-N 3.24Å; F159-I161 VanDerWaalsContact C-N 3.35Å; F159-I161 PolarHBondContact O-N 2.86Å; I161-F163 VanDerWaalsContact C-N 3.28Å; I161-F163 PolarHBondContact O-N 3.47Å; I161-A164 PolarHBondContact O-N 2.95Å; I161-Y165 WeakPolarHBondContact O-CB 3.35Å; I161-Y165 PolarHBondContact O-N 3.46Å; I161-A183 HydrophobicContact CD1-CB 3.41Å; I161-A183 VanDerWaalsContact CD1-CB 3.41Å; I161-A183 HydrophobicContact CG1-CB 3.69Å; I161-N190 HydrophobicContact CD1-CB 4.05Å; I161-N190 HydrophobicContact CG1-CB 4.24Å; I161-W193 HydrophobicContact CD1-CB 3.62Å; I161-W193 HydrophobicContact CG1-CB 4.08Å; I161-W193 HydrophobicContact CG2-CB 3.91Å; I161-W193 HydrophobicContact CG2-CG 4.38Å; I161-I424 HydrophobicContact CB-CD1 4.49Å; I161-I424 HydrophobicContact CG1-CD1 4.13Å; I161-I424 HydrophobicContact CG2-CG2 3.87Å; I161-M428 HydrophobicContact CG2-CE 3.47Å; I161-M428 VanDerWaalsContact CG2-CE 3.47Å
162	L	98.8	Very high	98.1	Very high	2 Å²	2	22 Å²	22	1%	0.01	12%	0.118	C	C	.	.	H	α-helix	trans	-61.6	-40	176	-69.3	179.7	0	0	0	111	L111 L112 L115 T158 F159 Y165 L166 M428 L431	L111-L162 HydrophobicContact CB-CB 4.23Å; L111-L162 HydrophobicContact CD1-CB 4.16Å; L112-L162 HydrophobicContact CD2-CD1 3.87Å; L112-L162 HydrophobicContact CD2-CD2 4.28Å; L112-L162 HydrophobicContact CG-CD1 3.92Å; L115-L162 HydrophobicContact CD1-CB 3.92Å; L115-L162 HydrophobicContact CD1-CD2 3.69Å; L115-L162 HydrophobicContact CD1-CG 4.32Å; T158-L162 HydrophobicContact CG2-CD1 3.73Å; T158-L162 HydrophobicContact CG2-CG 4.05Å; T158-L162 WeakPolarHBondContact O-CB 3.42Å; T158-L162 VanDerWaalsContact O-CG 3.28Å; T158-L162 WeakPolarHBondContact O-CG 3.36Å; T158-L162 PolarHBondContact O-N 3.31Å; F159-L162 PolarHBondContact O-N 3.07Å; L162-Y165 PolarHBondContact O-N 3.08Å; L162-L166 WeakPolarHBondContact O-CB 3.29Å; L162-L166 PolarHBondContact O-N 3.12Å; L162-M428 HydrophobicContact CD2-CE 4.02Å; L162-L431 HydrophobicContact CD2-CD1 3.84Å
163	F	98.8	Very high	98.1	Very high	65 Å²	65	23.5 Å²	23.5	29%	0.285	12%	0.124	S	C	.	.	H	α-helix	trans	-69.7	-44.6	178.3	-161.3	179.7	0	0	0	111.7	L111 F159 I161 Y165 L166 M167 L179	L111-F163 HydrophobicContact CD1-CB 3.75Å; L111-F163 HydrophobicContact CD1-CG 4.32Å; L111-F163 HydrophobicContact CD2-CB 4.09Å; L111-F163 HydrophobicContact CD2-CD2 3.94Å; L111-F163 HydrophobicContact CD2-CG 4.01Å; F159-F163 HydrophobicContact CE1-CD1 4.11Å; F159-F163 HydrophobicContact CZ-CD1 4.09Å; F159-F163 WeakPolarHBondContact O-CB 3.28Å; F159-F163 PolarHBondContact O-N 2.76Å; I161-F163 VanDerWaalsContact C-N 3.28Å; I161-F163 PolarHBondContact O-N 3.47Å; F163-Y165 VanDerWaalsContact C-N 3.25Å; F163-Y165 PolarHBondContact O-N 3.09Å; F163-L166 WeakPolarHBondContact O-CB 3.31Å; F163-L166 PolarHBondContact O-N 3.26Å; F163-M167 HydrophobicContact CD2-CE 4.11Å; F163-M167 HydrophobicContact CD2-CG 4Å; F163-M167 HydrophobicContact CE2-CE 3.67Å; F163-M167 HydrophobicContact CE2-CG 3.97Å; F163-M167 HydrophobicContact CE2-SD 3.97Å; F163-M167 WeakPolarHBondContact O-CG 3.33Å; F163-M167 PolarHBondContact O-N 3.43Å; F163-L179 HydrophobicContact CB-CD1 3.98Å; F163-L179 HydrophobicContact CB-CD2 4.46Å; F163-L179 HydrophobicContact CD1-CD1 3.77Å; F163-L179 HydrophobicContact CD1-CD2 3.56Å; F163-L179 HydrophobicContact CD1-CG 4.32Å; F163-L179 HydrophobicContact CD2-CD1 3.67Å; F163-L179 HydrophobicContact CE1-CD1 4.14Å; F163-L179 HydrophobicContact CE1-CD2 3.94Å; F163-L179 HydrophobicContact CE2-CD1 4.04Å; F163-L179 HydrophobicContact CG-CD1 3.51Å; F163-L179 HydrophobicContact CG-CD2 4.09Å; F163-L179 HydrophobicContact CG-CG 4.42Å; F163-L179 HydrophobicContact CZ-CD1 4.26Å
164	A	98.8	Very high	98.1	Very high	2 Å²	2	30.4 Å²	30.4	2%	0.017	15%	0.154	C	C	.	.	H	α-helix	trans	-57.5	-42.3	173.9	0	0	0	0	0	111	F160 I161 M167 T168 S176 L179	F160-A164 WeakPolarHBondContact O-CB 3.36Å; F160-A164 PolarHBondContact O-N 3.36Å; I161-A164 PolarHBondContact O-N 2.95Å; A164-M167 PolarHBondContact O-N 2.66Å; A164-T168 PolarHBondContact O-N 2.76Å; A164-T168 PolarHBondContact O-OG1 3.03Å; A164-S176 WeakPolarHBondContact CB-O 3.38Å; A164-S176 WeakPolarHBondContact O-CB 3.32Å; A164-S176 PolarHBondContact O-OG 3.42Å; A164-L179 HydrophobicContact CB-CB 3.84Å
165	Y	98.7	Very high	98.1	Very high	4 Å²	4	32.2 Å²	32.2	2%	0.016	17%	0.169	C	C	.	.	H	α-helix	trans	-66.4	-42.3	177.1	-174	-128.1	0	0	0	112.1	L115 L119 I161 L162 F163 M167 T168 L169 F196 T200 M428 H432	L115-Y165 HydrophobicContact CD2-CD1 3.67Å; L115-Y165 HydrophobicContact CD2-CE1 4.19Å; L115-Y165 HydrophobicContact CD2-CG 4.47Å; L119-Y165 HydrophobicContact CD1-CE1 4.32Å; I161-Y165 WeakPolarHBondContact O-CB 3.35Å; I161-Y165 PolarHBondContact O-N 3.46Å; L162-Y165 PolarHBondContact O-N 3.08Å; F163-Y165 VanDerWaalsContact C-N 3.25Å; F163-Y165 PolarHBondContact O-N 3.09Å; Y165-M167 PolarHBondContact O-N 2.84Å; Y165-T168 VanDerWaalsContact O-CB 3.26Å; Y165-T168 WeakPolarHBondContact O-CB 2.95Å; Y165-T168 PolarHBondContact O-N 3.24Å; Y165-T168 VanDerWaalsContact O-N 3.11Å; Y165-L169 HydrophobicContact CD1-CD1 4.34Å; Y165-L169 HydrophobicContact CE1-CD1 3.88Å; Y165-L169 HydrophobicContact CE1-CG 4.37Å; Y165-L169 HydrophobicContact CE2-CD2 4.12Å; Y165-L169 HydrophobicContact CE2-CG 4.17Å; Y165-L169 WeakPolarHBondContact O-CG 3.33Å; Y165-L169 PolarHBondContact O-N 3.13Å; Y165-F196 HydrophobicContact CD2-CD1 4.49Å; Y165-F196 HydrophobicContact CD2-CE1 4.17Å; Y165-F196 AromaticContact CE2-CE1 3.96Å; Y165-F196 HydrophobicContact CE2-CE1 3.96Å; Y165-T200 HydrophobicContact CE2-CG2 3.89Å; Y165-M428 HydrophobicContact CD1-CE 4.23Å; Y165-M428 HydrophobicContact CD1-SD 3.99Å; Y165-M428 HydrophobicContact CE1-SD 4.35Å; Y165-M428 HydrophobicContact CG-CE 4.28Å; Y165-M428 HydrophobicContact CG-SD 4.41Å; Y165-H432 AromaticContact CE1-CE1 3.66Å; Y165-H432 AromaticContact CZ-CE1 3.61Å; Y165-H432 AromaticContact CZ-NE2 3.62Å; Y165-H432 PolarHBondContact OH-CE1 2.87Å; Y165-H432 PolarHBondContact OH-NE2 3.37Å
166	L	98.6	Very high	98.2	Very high	4 Å²	4	32.2 Å²	32.2	2%	0.021	17%	0.17	C	C	.	.	H	α-helix	trans	-58.4	-47.3	175	-176.3	65.1	0	0	0	111.4	L111 L114 L115 L162 F163 T168 L169 Y170	L111-L166 HydrophobicContact CD2-CD2 3.77Å; L114-L166 HydrophobicContact CB-CD1 4.12Å; L114-L166 HydrophobicContact CB-CD2 3.92Å; L114-L166 HydrophobicContact CD1-CD2 3.77Å; L115-L166 HydrophobicContact CD2-CB 3.79Å; L115-L166 HydrophobicContact CD2-CD1 3.78Å; L115-L166 HydrophobicContact CD2-CG 4.41Å; L115-L166 HydrophobicContact CG-CB 4.2Å; L115-L166 HydrophobicContact CG-CD1 4.06Å; L162-L166 WeakPolarHBondContact O-CB 3.29Å; L162-L166 PolarHBondContact O-N 3.12Å; F163-L166 WeakPolarHBondContact O-CB 3.31Å; F163-L166 PolarHBondContact O-N 3.26Å; L166-T168 VanDerWaalsContact C-N 3.27Å; L166-T168 PolarHBondContact O-N 2.78Å; L166-L169 WeakPolarHBondContact O-CB 3.45Å; L166-L169 PolarHBondContact O-N 2.84Å; L166-L169 VanDerWaalsContact O-N 3.11Å; L166-Y170 HydrophobicContact CD1-CD2 4.04Å; L166-Y170 HydrophobicContact CD1-CE2 3.5Å; L166-Y170 VanDerWaalsContact CD1-CE2 3.5Å; L166-Y170 HydrophobicContact CD2-CE2 4.24Å; L166-Y170 HydrophobicContact CG-CD2 3.92Å; L166-Y170 HydrophobicContact CG-CE2 3.65Å; L166-Y170 WeakPolarHBondContact O-CD2 3.43Å; L166-Y170 PolarHBondContact O-N 3.24Å; L166-Y170 VanDerWaalsContact O-N 3.1Å
167	M	98.6	Very high	98.2	Very high	33 Å²	33	32.5 Å²	32.5	16%	0.163	17%	0.172	C	C	.	.	H	α-helix	trans	-61.6	-34.8	176.2	-67.6	-58.1	92.6	0	0	112.4	F163 A164 Y165 Y170 G171 C172 A175 L179	F163-M167 HydrophobicContact CD2-CE 4.11Å; F163-M167 HydrophobicContact CD2-CG 4Å; F163-M167 HydrophobicContact CE2-CE 3.67Å; F163-M167 HydrophobicContact CE2-CG 3.97Å; F163-M167 HydrophobicContact CE2-SD 3.97Å; F163-M167 WeakPolarHBondContact O-CG 3.33Å; F163-M167 PolarHBondContact O-N 3.43Å; A164-M167 PolarHBondContact O-N 2.66Å; Y165-M167 PolarHBondContact O-N 2.84Å; M167-Y170 HydrophobicContact CE-CD2 3.86Å; M167-Y170 HydrophobicContact CE-CE2 4.41Å; M167-Y170 PolarHBondContact O-N 3.01Å; M167-G171 PolarHBondContact O-N 3.32Å; M167-C172 HydrophobicContact CB-CB 4.24Å; M167-C172 PolarHBondContact O-N 3.38Å; M167-C172 HydrophobicContact SD-CB 4.29Å; M167-A175 HydrophobicContact CG-CB 4.28Å; M167-L179 HydrophobicContact CG-CD1 3.64Å
168	T	98.1	Very high	98.2	Very high	8 Å²	8	38 Å²	38	5%	0.049	20%	0.2	C	C	.	.	H	α-helix	trans	-60.5	-46.4	172.4	-54.8	0	0	0	0	111.1	A164 Y165 L166 Y170 G171 S176 C197 V201 Y261	A164-T168 PolarHBondContact O-N 2.76Å; A164-T168 PolarHBondContact O-OG1 3.03Å; Y165-T168 VanDerWaalsContact O-CB 3.26Å; Y165-T168 WeakPolarHBondContact O-CB 2.95Å; Y165-T168 PolarHBondContact O-N 3.24Å; Y165-T168 VanDerWaalsContact O-N 3.11Å; L166-T168 VanDerWaalsContact C-N 3.27Å; L166-T168 PolarHBondContact O-N 2.78Å; T168-Y170 PolarHBondContact O-N 3.14Å; T168-G171 PolarHBondContact O-N 3.17Å; T168-S176 PolarHBondContact OG1-OG 3.34Å; T168-C197 HydrophobicContact CG2-CB 4.32Å; T168-C197 WeakPolarHBondContact OG1-CB 3.49Å; T168-V201 HydrophobicContact CG2-CG2 3.62Å; T168-Y261 PolarHBondContact OG1-OH 2.9Å
169	L	96.8	Very high	98.2	Very high	47 Å²	47	38.9 Å²	38.9	25%	0.246	21%	0.205	C	C	.	.	H	α-helix	trans	-66.9	-21.2	178.4	-64.8	177.8	0	0	0	113.6	L115 K118 L119 Y165 L166	L115-L169 HydrophobicContact CD2-CD1 3.78Å; K118-L169 WeakPolarHBondContact CE-O 3.31Å; K118-L169 HydrophobicContact CG-CB 4.04Å; K118-L169 HydrophobicContact CG-CD1 4.11Å; K118-L169 PolarHBondContact NZ-O 3.23Å; L119-L169 HydrophobicContact CD2-CD1 3.77Å; L119-L169 HydrophobicContact CD2-CD2 4.28Å; L119-L169 HydrophobicContact CG-CD1 3.98Å; Y165-L169 HydrophobicContact CD1-CD1 4.34Å; Y165-L169 HydrophobicContact CE1-CD1 3.88Å; Y165-L169 HydrophobicContact CE1-CG 4.37Å; Y165-L169 HydrophobicContact CE2-CD2 4.12Å; Y165-L169 HydrophobicContact CE2-CG 4.17Å; Y165-L169 WeakPolarHBondContact O-CG 3.33Å; Y165-L169 PolarHBondContact O-N 3.13Å; L166-L169 WeakPolarHBondContact O-CB 3.45Å; L166-L169 PolarHBondContact O-N 2.84Å; L166-L169 VanDerWaalsContact O-N 3.11Å
170	Y	96.8	Very high	98.2	Very high	119 Å²	119	37.1 Å²	37.1	47%	0.467	20%	0.198	S	C	.	.	T	Hydrogen-bonded Turn	trans	-88.1	-4.4	171.3	-76.8	-70	0	0	0	113.6	K118 L166 M167 T168 C172	K118-Y170 HydrophobicContact CD-CE1 4.39Å; L166-Y170 HydrophobicContact CD1-CD2 4.04Å; L166-Y170 HydrophobicContact CD1-CE2 3.5Å; L166-Y170 VanDerWaalsContact CD1-CE2 3.5Å; L166-Y170 HydrophobicContact CD2-CE2 4.24Å; L166-Y170 HydrophobicContact CG-CD2 3.92Å; L166-Y170 HydrophobicContact CG-CE2 3.65Å; L166-Y170 WeakPolarHBondContact O-CD2 3.43Å; L166-Y170 PolarHBondContact O-N 3.24Å; L166-Y170 VanDerWaalsContact O-N 3.1Å; M167-Y170 HydrophobicContact CE-CD2 3.86Å; M167-Y170 HydrophobicContact CE-CE2 4.41Å; M167-Y170 PolarHBondContact O-N 3.01Å; T168-Y170 PolarHBondContact O-N 3.14Å; Y170-C172 VanDerWaalsContact C-N 3.28Å
171	G	96.5	Very high	98.2	Very high	42 Å²	42	38.9 Å²	38.9	43%	0.433	21%	0.21	S	C	.	.	T	Hydrogen-bonded Turn	trans	79.8	6	-176.2	0	0	0	0	0	114.3	M167 T168 H173	M167-G171 PolarHBondContact O-N 3.32Å; T168-G171 PolarHBondContact O-N 3.17Å; G171-H173 VanDerWaalsContact C-N 3.28Å; G171-H173 PolarHBondContact O-CD2 3.33Å; G171-H173 PolarHBondContact O-N 3.09Å; G171-H173 PolarHBondContact O-NE2 3.16Å
172	C	97.4	Very high	98.1	Very high	60 Å²	60	40.6 Å²	40.6	41%	0.405	22%	0.222	S	C	.	.			trans	-84.7	64.9	179.3	-65.9	0	0	0	0	111.1	M167 Y170 K174 A175 S176	M167-C172 HydrophobicContact CB-CB 4.24Å; M167-C172 PolarHBondContact O-N 3.38Å; M167-C172 HydrophobicContact SD-CB 4.29Å; Y170-C172 VanDerWaalsContact C-N 3.28Å; C172-K174 PolarHBondContact O-N 2.94Å; C172-A175 HydrophobicContact CB-CB 4.28Å; C172-A175 PolarHBondContact O-N 2.64Å; C172-S176 WeakPolarHBondContact O-CB 3.49Å; C172-S176 PolarHBondContact O-N 3.26Å
173	H	97.6	Very high	98.1	Very high	32 Å²	32	40.5 Å²	40.5	15%	0.148	22%	0.221	C	C	.	.	H	α-helix	trans	-64.9	-32.5	-170.1	-59.4	-62.2	0	0	0	114.7	G171 S176 A177 V201 V257 P260 Y261	G171-H173 VanDerWaalsContact C-N 3.28Å; G171-H173 PolarHBondContact O-CD2 3.33Å; G171-H173 PolarHBondContact O-N 3.09Å; G171-H173 PolarHBondContact O-NE2 3.16Å; H173-S176 WeakPolarHBondContact O-CB 3.27Å; H173-S176 PolarHBondContact O-N 2.99Å; H173-A177 WeakPolarHBondContact O-CB 3.32Å; H173-A177 PolarHBondContact O-N 3.19Å; H173-V201 VanDerWaalsContact CE1-CG2 3.42Å; H173-V201 WeakPolarHBondContact CE1-CG2 3.48Å; H173-V257 WeakPolarHBondContact CD2-CG1 3.21Å; H173-V257 WeakPolarHBondContact NE2-CG1 3.38Å; H173-P260 HydrophobicContact CB-CG 4.28Å; H173-Y261 HydrophobicContact CB-CE2 3.84Å; H173-Y261 AromaticContact ND1-CE2 3.68Å; H173-Y261 AromaticContact ND1-CZ 3.79Å; H173-Y261 PolarHBondContact ND1-OH 3.16Å
174	K	97.9	Very high	98.1	Very high	149 Å²	149	38 Å²	38	65%	0.648	21%	0.211	S	C	*	.	H	α-helix	trans	-65.9	-47.1	175.5	-60	-178	-170.4	-176.6	0	111.7	C172 S176 A177 L178 W259 P260	C172-K174 PolarHBondContact O-N 2.94Å; K174-S176 VanDerWaalsContact C-N 3.32Å; K174-A177 PolarHBondContact O-N 2.74Å; K174-L178 PolarHBondContact O-N 3.33Å; K174-W259 HydrophobicContact CD-CZ2 4.43Å; K174-W259 HydrophobicContact CG-CZ2 4.4Å; K174-P260 HydrophobicContact CG-CG 4.12Å
175	A	98.3	Very high	98.1	Very high	41 Å²	41	40.6 Å²	40.6	34%	0.339	23%	0.225	S	C	.	.	H	α-helix	trans	-64	-40.5	176.2	0	0	0	0	0	111.1	M167 C172 L178 L179	M167-A175 HydrophobicContact CG-CB 4.28Å; C172-A175 HydrophobicContact CB-CB 4.28Å; C172-A175 PolarHBondContact O-N 2.64Å; A175-L178 PolarHBondContact O-N 3.49Å; A175-L179 VanDerWaalsContact O-CG 3.32Å; A175-L179 WeakPolarHBondContact O-CG 3.34Å; A175-L179 PolarHBondContact O-N 3.08Å
176	S	98.5	Very high	98	Very high	1 Å²	1	40.5 Å²	40.5	1%	0.007	22%	0.224	C	C	.	.	H	α-helix	trans	-58.1	-47.3	173.8	-179.6	0	0	0	0	112.4	A164 T168 C172 H173 K174 L179 G180 Y261	A164-S176 WeakPolarHBondContact CB-O 3.38Å; A164-S176 WeakPolarHBondContact O-CB 3.32Å; A164-S176 PolarHBondContact O-OG 3.42Å; T168-S176 PolarHBondContact OG1-OG 3.34Å; C172-S176 WeakPolarHBondContact O-CB 3.49Å; C172-S176 PolarHBondContact O-N 3.26Å; H173-S176 WeakPolarHBondContact O-CB 3.27Å; H173-S176 PolarHBondContact O-N 2.99Å; K174-S176 VanDerWaalsContact C-N 3.32Å; S176-L179 PolarHBondContact O-N 3.22Å; S176-G180 PolarHBondContact O-N 3.01Å; S176-Y261 VanDerWaalsContact CB-OH 3.3Å; S176-Y261 WeakPolarHBondContact CB-OH 3.16Å; S176-Y261 VanDerWaalsContact OG-CE1 3.3Å; S176-Y261 WeakPolarHBondContact OG-CE1 3.5Å; S176-Y261 PolarHBondContact OG-OH 3.26Å; S176-Y261 VanDerWaalsContact OG-OH 3.09Å
177	A	98.5	Very high	97.8	Very high	6 Å²	6	41.7 Å²	41.7	5%	0.05	23%	0.229	C	C	.	.	H	α-helix	trans	-63.6	-41.6	177.5	0	0	0	0	0	112.3	H173 K174 G180 V181 P260 Y261 V264	H173-A177 WeakPolarHBondContact O-CB 3.32Å; H173-A177 PolarHBondContact O-N 3.19Å; K174-A177 PolarHBondContact O-N 2.74Å; A177-G180 CarbonylContact O-C 3.5Å; A177-G180 VanDerWaalsContact O-CA 3.31Å; A177-G180 WeakPolarHBondContact O-CA 3.21Å; A177-G180 PolarHBondContact O-N 3.22Å; A177-V181 PolarHBondContact O-N 3.11Å; A177-P260 HydrophobicContact CB-CB 3.54Å; A177-P260 WeakPolarHBondContact CB-O 3.31Å; A177-Y261 HydrophobicContact CB-CD1 4.34Å; A177-V264 HydrophobicContact CB-CG2 3.96Å
178	L	98.4	Very high	97.6	Very high	117 Å²	117	40.7 Å²	40.7	61%	0.613	22%	0.223	S	C	*	.	H	α-helix	trans	-60.9	-45.7	175.3	-179.7	63.9	0	0	0	112	K174 A175 G180 V181 C182	K174-L178 PolarHBondContact O-N 3.33Å; A175-L178 PolarHBondContact O-N 3.49Å; L178-G180 PolarHBondContact O-N 2.71Å; L178-V181 WeakPolarHBondContact O-CB 3.3Å; L178-V181 PolarHBondContact O-N 2.92Å; L178-V181 VanDerWaalsContact O-N 3.13Å; L178-C182 PolarHBondContact O-N 3.42Å; L178-C182 VanDerWaalsContact O-N 3.13Å
179	L	98.6	Very high	97.4	Very high	23 Å²	23	42.3 Å²	42.3	12%	0.12	23%	0.234	C	C	.	.	H	α-helix	trans	-63.1	-32.9	173	-68.8	165.3	0	0	0	111.5	F160 F163 A164 M167 A175 S176 C182 A183	F160-L179 HydrophobicContact CD1-CD2 3.85Å; F160-L179 HydrophobicContact CE1-CD2 4.19Å; F163-L179 HydrophobicContact CB-CD1 3.98Å; F163-L179 HydrophobicContact CB-CD2 4.46Å; F163-L179 HydrophobicContact CD1-CD1 3.77Å; F163-L179 HydrophobicContact CD1-CD2 3.56Å; F163-L179 HydrophobicContact CD1-CG 4.32Å; F163-L179 HydrophobicContact CD2-CD1 3.67Å; F163-L179 HydrophobicContact CE1-CD1 4.14Å; F163-L179 HydrophobicContact CE1-CD2 3.94Å; F163-L179 HydrophobicContact CE2-CD1 4.04Å; F163-L179 HydrophobicContact CG-CD1 3.51Å; F163-L179 HydrophobicContact CG-CD2 4.09Å; F163-L179 HydrophobicContact CG-CG 4.42Å; F163-L179 HydrophobicContact CZ-CD1 4.26Å; A164-L179 HydrophobicContact CB-CB 3.84Å; M167-L179 HydrophobicContact CG-CD1 3.64Å; A175-L179 VanDerWaalsContact O-CG 3.32Å; A175-L179 WeakPolarHBondContact O-CG 3.34Å; A175-L179 PolarHBondContact O-N 3.08Å; S176-L179 PolarHBondContact O-N 3.22Å; L179-C182 WeakPolarHBondContact O-CB 3.19Å; L179-C182 PolarHBondContact O-N 2.98Å; L179-A183 PolarHBondContact O-N 3.19Å
180	G	98.5	Very high	97.5	Very high	1 Å²	1	40.1 Å²	40.1	1%	0.01	22%	0.222	C	C	.	.	H	α-helix	trans	-60.9	-41.1	171	0	0	0	0	0	113	S176 A177 L178 A183 V184	S176-G180 PolarHBondContact O-N 3.01Å; A177-G180 CarbonylContact O-C 3.5Å; A177-G180 VanDerWaalsContact O-CA 3.31Å; A177-G180 WeakPolarHBondContact O-CA 3.21Å; A177-G180 PolarHBondContact O-N 3.22Å; L178-G180 PolarHBondContact O-N 2.71Å; G180-A183 WeakPolarHBondContact O-CB 3.35Å; G180-A183 PolarHBondContact O-N 2.87Å; G180-V184 WeakPolarHBondContact O-CG2 3.4Å; G180-V184 PolarHBondContact O-N 3.02Å
181	V	98.6	Very high	97.5	Very high	58 Å²	58	35.8 Å²	35.8	35%	0.352	21%	0.207	S	C	.	.	H	α-helix	trans	-60	-47.9	171.8	177.1	0	0	0	0	110	A177 L178 A183 V184 L185 V264	A177-V181 PolarHBondContact O-N 3.11Å; L178-V181 WeakPolarHBondContact O-CB 3.3Å; L178-V181 PolarHBondContact O-N 2.92Å; L178-V181 VanDerWaalsContact O-N 3.13Å; V181-A183 VanDerWaalsContact C-N 3.28Å; V181-A183 PolarHBondContact O-N 3.35Å; V181-V184 PolarHBondContact O-N 3.43Å; V181-V184 VanDerWaalsContact O-N 3.15Å; V181-L185 HydrophobicContact CG1-CD1 4.37Å; V181-L185 WeakPolarHBondContact O-CG 3.49Å; V181-L185 PolarHBondContact O-N 2.86Å; V181-V264 HydrophobicContact CG2-CB 4.48Å; V181-V264 HydrophobicContact CG2-CG1 4.08Å; V181-V264 HydrophobicContact CG2-CG2 3.66Å
182	C	98.4	Very high	97.6	Very high	39 Å²	39	34.7 Å²	34.7	26%	0.264	19%	0.191	S	C	.	.	H	α-helix	trans	-57.4	-42.5	176.1	-62.5	0	0	0	0	111.6	F160 L178 L179 L185 F186	F160-C182 HydrophobicContact CB-CB 4.37Å; F160-C182 HydrophobicContact CD1-CB 3.46Å; F160-C182 VanDerWaalsContact CD1-CB 3.46Å; F160-C182 HydrophobicContact CD2-CB 4.12Å; F160-C182 HydrophobicContact CE1-CB 3.65Å; F160-C182 HydrophobicContact CE2-CB 4.29Å; F160-C182 HydrophobicContact CG-CB 3.72Å; F160-C182 HydrophobicContact CZ-CB 4.07Å; L178-C182 PolarHBondContact O-N 3.42Å; L178-C182 VanDerWaalsContact O-N 3.13Å; L179-C182 WeakPolarHBondContact O-CB 3.19Å; L179-C182 PolarHBondContact O-N 2.98Å; C182-L185 PolarHBondContact O-N 2.89Å; C182-F186 WeakPolarHBondContact O-CD2 3.37Å; C182-F186 PolarHBondContact O-N 3.46Å
183	A	98.4	Very high	97.7	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-62.2	-46.4	175.3	0	0	0	0	0	112.3	F160 I161 L179 G180 V181 L185 F186 R187 N190	F160-A183 HydrophobicContact CB-CB 3.72Å; I161-A183 HydrophobicContact CD1-CB 3.41Å; I161-A183 VanDerWaalsContact CD1-CB 3.41Å; I161-A183 HydrophobicContact CG1-CB 3.69Å; L179-A183 PolarHBondContact O-N 3.19Å; G180-A183 WeakPolarHBondContact O-CB 3.35Å; G180-A183 PolarHBondContact O-N 2.87Å; V181-A183 VanDerWaalsContact C-N 3.28Å; V181-A183 PolarHBondContact O-N 3.35Å; A183-L185 PolarHBondContact O-N 3.34Å; A183-F186 WeakPolarHBondContact O-CB 3.42Å; A183-F186 PolarHBondContact O-N 2.86Å; A183-R187 PolarHBondContact O-N 3.27Å; A183-R187 VanDerWaalsContact O-N 3.12Å; A183-N190 HydrophobicContact CB-CB 4.01Å; A183-N190 PolarHBondContact O-ND2 3.42Å
184	V	98.4	Very high	97.7	Very high	12 Å²	12	30.9 Å²	30.9	7%	0.073	17%	0.168	C	C	.	.	H	α-helix	trans	-58.5	-39.3	177.1	171.4	0	0	0	0	110.9	L66 G180 V181 F186 R187 Q188 N190 I191 V194 F268	L66-V184 HydrophobicContact CD1-CG1 4.09Å; L66-V184 WeakPolarHBondContact CD1-O 3.37Å; G180-V184 WeakPolarHBondContact O-CG2 3.4Å; G180-V184 PolarHBondContact O-N 3.02Å; V181-V184 PolarHBondContact O-N 3.43Å; V181-V184 VanDerWaalsContact O-N 3.15Å; V184-F186 PolarHBondContact O-N 3.49Å; V184-R187 WeakPolarHBondContact CA-O 3.47Å; V184-R187 CarbonylContact O-C 3.54Å; V184-R187 PolarHBondContact O-N 3.42Å; V184-R187 VanDerWaalsContact O-N 3.13Å; V184-R187 VanDerWaalsContact O-O 3.07Å; V184-Q188 PolarHBondContact O-N 3.42Å; V184-N190 HydrophobicContact CG2-CB 4.43Å; V184-I191 HydrophobicContact CG2-CB 4.18Å; V184-I191 HydrophobicContact CG2-CD1 4.17Å; V184-V194 HydrophobicContact CG2-CG2 4.24Å; V184-F268 HydrophobicContact CG1-CD2 3.74Å; V184-F268 HydrophobicContact CG1-CE2 4.05Å
185	L	97.8	Very high	97.7	Very high	57 Å²	57	26.2 Å²	26.2	30%	0.298	16%	0.157	S	C	.	.	H	α-helix	trans	-63.5	-24.1	175.6	-69.3	174.9	0	0	0	113.8	L66 G68 V181 C182 A183	L66-L185 CarbonylContact C-O 3.59Å; L66-L185 WeakPolarHBondContact CA-O 3.11Å; L66-L185 HydrophobicContact CB-CD2 4.47Å; L66-L185 WeakPolarHBondContact CB-O 3.16Å; L66-L185 HydrophobicContact CD1-CD2 4.43Å; L66-L185 VanDerWaalsContact O-O 3.11Å; G68-L185 VanDerWaalsContact CA-O 3.27Å; G68-L185 WeakPolarHBondContact CA-O 3.31Å; G68-L185 PolarHBondContact N-O 2.96Å; V181-L185 HydrophobicContact CG1-CD1 4.37Å; V181-L185 WeakPolarHBondContact O-CG 3.49Å; V181-L185 PolarHBondContact O-N 2.86Å; C182-L185 PolarHBondContact O-N 2.89Å; A183-L185 PolarHBondContact O-N 3.34Å
186	F	97.5	Very high	97.7	Very high	1 Å²	1	24.2 Å²	24.2	0%	0.004	14%	0.141	C	C	.	.	H	α-helix	trans	-78.7	-43.4	170.4	-87.2	-105.5	0	0	0	111.6	G68 L69 V72 F104 T153 F160 C182 A183 V184	G68-F186 WeakPolarHBondContact O-CE2 3.48Å; L69-F186 HydrophobicContact CB-CD1 4.24Å; L69-F186 HydrophobicContact CB-CE1 3.98Å; L69-F186 HydrophobicContact CD1-CE1 3.86Å; V72-F186 HydrophobicContact CB-CE2 4.38Å; V72-F186 HydrophobicContact CB-CZ 4.12Å; V72-F186 HydrophobicContact CG2-CE2 3.82Å; V72-F186 HydrophobicContact CG2-CZ 4.07Å; F104-F186 HydrophobicContact CE2-CE1 4.03Å; F104-F186 AromaticContact CE2-CZ 3.87Å; F104-F186 HydrophobicContact CE2-CZ 3.87Å; F104-F186 HydrophobicContact CZ-CE1 4.21Å; F104-F186 AromaticContact CZ-CZ 3.65Å; F104-F186 HydrophobicContact CZ-CZ 3.65Å; T153-F186 WeakPolarHBondContact O-CD1 3.39Å; F160-F186 AromaticContact CD2-CD2 3.95Å; F160-F186 HydrophobicContact CD2-CD2 3.95Å; F160-F186 AromaticContact CD2-CE2 3.78Å; F160-F186 HydrophobicContact CD2-CE2 3.78Å; F160-F186 HydrophobicContact CD2-CZ 4.48Å; F160-F186 HydrophobicContact CE2-CD2 4.09Å; F160-F186 AromaticContact CE2-CE2 3.45Å; F160-F186 HydrophobicContact CE2-CE2 3.45Å; F160-F186 VanDerWaalsContact CE2-CE2 3.45Å; F160-F186 HydrophobicContact CE2-CZ 4.03Å; C182-F186 WeakPolarHBondContact O-CD2 3.37Å; C182-F186 PolarHBondContact O-N 3.46Å; A183-F186 WeakPolarHBondContact O-CB 3.42Å; A183-F186 PolarHBondContact O-N 2.86Å; V184-F186 PolarHBondContact O-N 3.49Å
187	R	95.2	Very high	97.7	Very high	30 Å²	30	24.3 Å²	24.3	11%	0.113	14%	0.141	C	C	.	.			trans	-151.1	129.5	-179.9	-58.3	-175.7	73	122.8	5.8	110.2	D154 A183 V184 T189 N190 Y421	D154-R187 IonicContact OD1-CZ 2.69Å; D154-R187 IonicContact OD1-NH1 2.94Å; D154-R187 PolarHBondContact OD1-NH1 2.92Å; D154-R187 IonicContact OD2-NH1 2.66Å; A183-R187 PolarHBondContact O-N 3.27Å; A183-R187 VanDerWaalsContact O-N 3.12Å; V184-R187 WeakPolarHBondContact CA-O 3.47Å; V184-R187 CarbonylContact O-C 3.54Å; V184-R187 PolarHBondContact O-N 3.42Å; V184-R187 VanDerWaalsContact O-N 3.13Å; V184-R187 VanDerWaalsContact O-O 3.07Å; R187-T189 PolarHBondContact O-N 3.49Å; R187-N190 WeakPolarHBondContact O-CB 3.38Å; R187-N190 PolarHBondContact O-N 3.43Å; R187-Y421 VanDerWaalsContact NH2-CE1 3.3Å
188	Q	94.2	Very high	97.7	Very high	11 Å²	11	24.8 Å²	24.8	5%	0.051	15%	0.145	C	C	.	.	G	3₁₀ helix	trans	-59.8	-36.4	-179.5	-60.5	97	-40.8	0	0	112.4	T64 L66 V184 N190 I191 F268 I278	T64-Q188 PolarHBondContact O-NE2 2.8Å; L66-Q188 HydrophobicContact CD1-CG 3.84Å; L66-Q188 HydrophobicContact CG-CG 4.04Å; V184-Q188 PolarHBondContact O-N 3.42Å; Q188-N190 PolarHBondContact O-N 2.9Å; Q188-I191 VanDerWaalsContact O-CG2 3.29Å; Q188-I191 WeakPolarHBondContact O-CG2 3.41Å; Q188-I191 PolarHBondContact O-N 3.34Å; Q188-I191 VanDerWaalsContact O-N 3.1Å; Q188-F268 HydrophobicContact CB-CE2 3.84Å; Q188-F268 HydrophobicContact CB-CZ 3.96Å; Q188-F268 HydrophobicContact CG-CE2 4.25Å; Q188-I278 HydrophobicContact CB-CG2 3.95Å; Q188-I278 VanDerWaalsContact CG-O 3.28Å; Q188-I278 WeakPolarHBondContact CG-O 3.28Å; Q188-I278 PolarHBondContact NE2-O 3.17Å
189	T	93.9	Very high	97.6	Very high	43 Å²	43	20.1 Å²	20.1	26%	0.264	13%	0.125	S	C	.	.	G	3₁₀ helix	trans	-60.9	-17.5	178.2	56.3	0	0	0	0	113.4	R187 I191 V192	R187-T189 PolarHBondContact O-N 3.49Å; T189-I191 PolarHBondContact O-N 2.85Å; T189-V192 WeakPolarHBondContact O-CB 3.37Å; T189-V192 PolarHBondContact O-N 2.6Å
190	N	97.9	Very high	97.5	Very high	1 Å²	1	19.6 Å²	19.6	1%	0.005	12%	0.123	C	C	.	.	G	3₁₀ helix	trans	-64.9	-15.3	175	-73.5	-21.7	0	0	0	113.7	S157 I161 A183 V184 R187 Q188 V192 W193 V194 I424	S157-N190 PolarHBondContact OG-ND2 2.76Å; S157-N190 PolarHBondContact OG-OD1 3.27Å; I161-N190 HydrophobicContact CD1-CB 4.05Å; I161-N190 HydrophobicContact CG1-CB 4.24Å; A183-N190 HydrophobicContact CB-CB 4.01Å; A183-N190 PolarHBondContact O-ND2 3.42Å; V184-N190 HydrophobicContact CG2-CB 4.43Å; R187-N190 WeakPolarHBondContact O-CB 3.38Å; R187-N190 PolarHBondContact O-N 3.43Å; Q188-N190 PolarHBondContact O-N 2.9Å; N190-V192 PolarHBondContact O-N 2.94Å; N190-W193 WeakPolarHBondContact O-CA 3.49Å; N190-W193 PolarHBondContact O-N 3.2Å; N190-V194 PolarHBondContact O-N 3.18Å; N190-I424 WeakPolarHBondContact OD1-CD1 3.5Å
191	I	98.1	Very high	97.4	Very high	28 Å²	28	20.4 Å²	20.4	14%	0.144	13%	0.128	C	C	.	.	H	α-helix	trans	-55.7	-33.3	172.5	-167.3	60.8	0	0	0	111.8	V184 Q188 T189 W193 V194 A195 V264 F268	V184-I191 HydrophobicContact CG2-CB 4.18Å; V184-I191 HydrophobicContact CG2-CD1 4.17Å; Q188-I191 VanDerWaalsContact O-CG2 3.29Å; Q188-I191 WeakPolarHBondContact O-CG2 3.41Å; Q188-I191 PolarHBondContact O-N 3.34Å; Q188-I191 VanDerWaalsContact O-N 3.1Å; T189-I191 PolarHBondContact O-N 2.85Å; I191-W193 VanDerWaalsContact C-N 3.27Å; I191-W193 PolarHBondContact O-N 3.18Å; I191-V194 HydrophobicContact CD1-CB 4.41Å; I191-V194 WeakPolarHBondContact O-CB 3.46Å; I191-V194 PolarHBondContact O-N 3.41Å; I191-A195 PolarHBondContact O-N 2.9Å; I191-V264 HydrophobicContact CD1-CG1 3.99Å; I191-F268 HydrophobicContact CB-CD1 4.07Å; I191-F268 HydrophobicContact CB-CD2 4.49Å; I191-F268 HydrophobicContact CB-CE1 4.16Å; I191-F268 HydrophobicContact CB-CG 4.22Å; I191-F268 HydrophobicContact CB-CZ 4.43Å; I191-F268 HydrophobicContact CD1-CB 3.89Å; I191-F268 HydrophobicContact CD1-CD1 4.42Å; I191-F268 HydrophobicContact CD1-CG 4.12Å; I191-F268 HydrophobicContact CG1-CB 4.15Å; I191-F268 HydrophobicContact CG1-CD1 3.73Å; I191-F268 HydrophobicContact CG1-CE1 4.28Å; I191-F268 HydrophobicContact CG1-CG 3.9Å; I191-F268 HydrophobicContact CG2-CD1 4.02Å; I191-F268 HydrophobicContact CG2-CE1 3.68Å; I191-F268 HydrophobicContact CG2-CZ 4.03Å
192	V	98.3	Very high	97.3	Very high	18 Å²	18	18.9 Å²	18.9	11%	0.109	12%	0.118	C	C	.	.	H	α-helix	trans	-63.6	-35	176.4	179.2	0	0	0	0	111.1	T189 N190 A195 F196 C406 L409 A410	T189-V192 WeakPolarHBondContact O-CB 3.37Å; T189-V192 PolarHBondContact O-N 2.6Å; N190-V192 PolarHBondContact O-N 2.94Å; V192-A195 WeakPolarHBondContact O-CB 3.31Å; V192-A195 PolarHBondContact O-N 2.84Å; V192-F196 PolarHBondContact O-N 3.32Å; V192-C406 HydrophobicContact CG1-CB 3.74Å; V192-C406 WeakPolarHBondContact CG1-O 3.35Å; V192-L409 HydrophobicContact CG1-CB 3.93Å; V192-L409 HydrophobicContact CG2-CB 4.11Å; V192-A410 HydrophobicContact CG1-CB 4.16Å
193	W	98.4	Very high	97.1	Very high	7 Å²	7	17.1 Å²	17.1	3%	0.027	11%	0.107	C	C	.	.	H	α-helix	trans	-83.1	-22.8	178.8	-62.8	108.1	0	0	0	113.1	I161 N190 I191 F196 C197 Y403 C406 A410 I424 P425 M428	I161-W193 HydrophobicContact CD1-CB 3.62Å; I161-W193 HydrophobicContact CG1-CB 4.08Å; I161-W193 HydrophobicContact CG2-CB 3.91Å; I161-W193 HydrophobicContact CG2-CG 4.38Å; N190-W193 WeakPolarHBondContact O-CA 3.49Å; N190-W193 PolarHBondContact O-N 3.2Å; I191-W193 VanDerWaalsContact C-N 3.27Å; I191-W193 PolarHBondContact O-N 3.18Å; W193-F196 HydrophobicContact CE3-CB 3.88Å; W193-F196 HydrophobicContact CE3-CD1 4.03Å; W193-F196 AromaticContact CE3-CG 3.92Å; W193-F196 HydrophobicContact CE3-CG 3.92Å; W193-F196 HydrophobicContact CZ3-CB 4.42Å; W193-F196 HydrophobicContact CZ3-CD1 4.34Å; W193-F196 HydrophobicContact CZ3-CD2 4.35Å; W193-F196 HydrophobicContact CZ3-CG 4.12Å; W193-F196 WeakPolarHBondContact O-CB 3.47Å; W193-F196 PolarHBondContact O-N 3.27Å; W193-C197 PolarHBondContact O-N 2.87Å; W193-C197 VanDerWaalsContact O-N 3.09Å; W193-C197 PolarHBondContact O-SG 3.16Å; W193-Y403 HydrophobicContact CH2-CE2 4.22Å; W193-Y403 HydrophobicContact CZ3-CE2 4.33Å; W193-C406 HydrophobicContact CZ3-CB 4.45Å; W193-A410 HydrophobicContact CZ2-CB 4.35Å; W193-I424 HydrophobicContact CD2-CB 4.39Å; W193-I424 HydrophobicContact CD2-CG2 3.38Å; W193-I424 HydrophobicContact CE3-CG2 3.95Å; W193-I424 HydrophobicContact CG-CG2 3.62Å; W193-I424 HydrophobicContact CH2-CG2 4.5Å; W193-I424 HydrophobicContact CZ2-CB 4.36Å; W193-I424 HydrophobicContact CZ2-CG2 3.99Å; W193-I424 HydrophobicContact CZ3-CG2 4.46Å; W193-P425 VanDerWaalsContact CH2-CA 3.42Å; W193-P425 HydrophobicContact CH2-CB 3.61Å; W193-P425 HydrophobicContact CH2-CG 4.31Å; W193-P425 HydrophobicContact CZ2-CB 3.49Å; W193-P425 VanDerWaalsContact CZ2-CB 3.49Å; W193-P425 VanDerWaalsContact CZ2-CD 3.44Å; W193-P425 HydrophobicContact CZ2-CG 3.67Å; W193-M428 HydrophobicContact CE3-CG 3.96Å; W193-M428 HydrophobicContact CH2-CB 4.41Å; W193-M428 HydrophobicContact CH2-CG 4.42Å; W193-M428 HydrophobicContact CZ3-CB 3.97Å; W193-M428 HydrophobicContact CZ3-CG 3.73Å
194	V	98.6	Very high	96.8	Very high	5 Å²	5	19.4 Å²	19.4	3%	0.03	13%	0.126	C	C	.	.	H	α-helix	trans	-66.5	-43.9	163.4	-178.5	0	0	0	0	109.9	V184 N190 I191 F196 C197 A198 Y261 V264	V184-V194 HydrophobicContact CG2-CG2 4.24Å; N190-V194 PolarHBondContact O-N 3.18Å; I191-V194 HydrophobicContact CD1-CB 4.41Å; I191-V194 WeakPolarHBondContact O-CB 3.46Å; I191-V194 PolarHBondContact O-N 3.41Å; V194-F196 VanDerWaalsContact C-N 3.29Å; V194-F196 PolarHBondContact O-N 3.2Å; V194-C197 WeakPolarHBondContact O-CB 3.49Å; V194-C197 PolarHBondContact O-N 3.26Å; V194-C197 VanDerWaalsContact O-N 3.14Å; V194-A198 PolarHBondContact O-N 3.1Å; V194-A198 VanDerWaalsContact O-N 3.14Å; V194-Y261 HydrophobicContact CG1-CD1 3.88Å; V194-V264 HydrophobicContact CG1-CB 4.33Å; V194-V264 HydrophobicContact CG1-CG1 4.16Å
195	A	98.3	Very high	96.6	Very high	51 Å²	51	22.7 Å²	22.7	42%	0.421	14%	0.139	S	C	.	.	H	α-helix	trans	-62.7	-36.1	173.2	0	0	0	0	0	112	I191 V192 C197 A198 G199	I191-A195 PolarHBondContact O-N 2.9Å; V192-A195 WeakPolarHBondContact O-CB 3.31Å; V192-A195 PolarHBondContact O-N 2.84Å; A195-C197 PolarHBondContact O-N 3.01Å; A195-A198 PolarHBondContact O-N 3.41Å; A195-G199 PolarHBondContact O-N 2.83Å
196	F	98.3	Very high	96.3	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-58.9	-45.2	170.8	177.6	-106.3	0	0	0	111.9	Y165 V192 W193 V194 A198 G199 T200 M399 Y403 C406 M428 H432	Y165-F196 HydrophobicContact CD2-CD1 4.49Å; Y165-F196 HydrophobicContact CD2-CE1 4.17Å; Y165-F196 AromaticContact CE2-CE1 3.96Å; Y165-F196 HydrophobicContact CE2-CE1 3.96Å; V192-F196 PolarHBondContact O-N 3.32Å; W193-F196 HydrophobicContact CE3-CB 3.88Å; W193-F196 HydrophobicContact CE3-CD1 4.03Å; W193-F196 AromaticContact CE3-CG 3.92Å; W193-F196 HydrophobicContact CE3-CG 3.92Å; W193-F196 HydrophobicContact CZ3-CB 4.42Å; W193-F196 HydrophobicContact CZ3-CD1 4.34Å; W193-F196 HydrophobicContact CZ3-CD2 4.35Å; W193-F196 HydrophobicContact CZ3-CG 4.12Å; W193-F196 WeakPolarHBondContact O-CB 3.47Å; W193-F196 PolarHBondContact O-N 3.27Å; V194-F196 VanDerWaalsContact C-N 3.29Å; V194-F196 PolarHBondContact O-N 3.2Å; F196-A198 PolarHBondContact O-N 3.5Å; F196-G199 CarbonylContact O-C 3.56Å; F196-G199 PolarHBondContact O-N 3.21Å; F196-G199 VanDerWaalsContact O-N 3.15Å; F196-T200 HydrophobicContact CD1-CG2 4.12Å; F196-T200 HydrophobicContact CD2-CG2 4.33Å; F196-T200 HydrophobicContact CE1-CG2 3.84Å; F196-T200 HydrophobicContact CE2-CG2 4.04Å; F196-T200 HydrophobicContact CG-CG2 4.38Å; F196-T200 HydrophobicContact CZ-CG2 3.82Å; F196-T200 WeakPolarHBondContact O-CG2 3.31Å; F196-T200 PolarHBondContact O-N 3.42Å; F196-M399 HydrophobicContact CD2-CE 4.47Å; F196-M399 HydrophobicContact CE1-CE 4.33Å; F196-M399 HydrophobicContact CE2-CE 3.3Å; F196-M399 HydrophobicContact CZ-CE 3.23Å; F196-Y403 AromaticContact CE2-CD2 3.81Å; F196-Y403 HydrophobicContact CE2-CD2 3.81Å; F196-Y403 HydrophobicContact CE2-CG 4.31Å; F196-Y403 HydrophobicContact CZ-CD2 4.16Å; F196-C406 HydrophobicContact CB-CB 4.23Å; F196-C406 HydrophobicContact CD2-CB 4.33Å; F196-M428 HydrophobicContact CE1-CG 4.45Å; F196-M428 HydrophobicContact CE1-SD 3.94Å; F196-H432 AromaticContact CZ-CE1 3.93Å
197	C	98.3	Very high	96	Very high	2 Å²	2	21.8 Å²	21.8	1%	0.014	13%	0.134	C	C	.	.	H	α-helix	trans	-57.6	-50.2	176.4	-67.3	0	0	0	0	111	T168 W193 V194 A195 G199 T200 V201 Y261	T168-C197 HydrophobicContact CG2-CB 4.32Å; T168-C197 WeakPolarHBondContact OG1-CB 3.49Å; W193-C197 PolarHBondContact O-N 2.87Å; W193-C197 VanDerWaalsContact O-N 3.09Å; W193-C197 PolarHBondContact O-SG 3.16Å; V194-C197 WeakPolarHBondContact O-CB 3.49Å; V194-C197 PolarHBondContact O-N 3.26Å; V194-C197 VanDerWaalsContact O-N 3.14Å; A195-C197 PolarHBondContact O-N 3.01Å; C197-G199 VanDerWaalsContact C-N 3.32Å; C197-G199 PolarHBondContact O-N 2.93Å; C197-T200 PolarHBondContact O-N 3.07Å; C197-T200 PolarHBondContact O-OG1 3.49Å; C197-V201 PolarHBondContact O-N 3.42Å; C197-Y261 HydrophobicContact CB-CD1 4.28Å; C197-Y261 HydrophobicContact CB-CE1 3.67Å
198	A	97.8	Very high	95.8	Very high	16 Å²	16	23.6 Å²	23.6	13%	0.132	15%	0.146	C	C	.	.	H	α-helix	trans	-59	-43.8	174.1	0	0	0	0	0	112.1	V194 A195 F196 T200 V201 V202 Y261	V194-A198 PolarHBondContact O-N 3.1Å; V194-A198 VanDerWaalsContact O-N 3.14Å; A195-A198 PolarHBondContact O-N 3.41Å; F196-A198 PolarHBondContact O-N 3.5Å; A198-T200 VanDerWaalsContact C-N 3.3Å; A198-T200 PolarHBondContact O-N 2.92Å; A198-V201 WeakPolarHBondContact O-CB 3.21Å; A198-V201 PolarHBondContact O-N 2.89Å; A198-V201 VanDerWaalsContact O-N 3.14Å; A198-V202 WeakPolarHBondContact O-CG2 3.49Å; A198-V202 PolarHBondContact O-N 2.93Å; A198-Y261 HydrophobicContact CB-CD1 4.45Å; A198-Y261 HydrophobicContact CB-CD2 3.92Å; A198-Y261 HydrophobicContact CB-CG 3.82Å
199	G	96.9	Very high	95.6	Very high	19 Å²	19	25.7 Å²	25.7	20%	0.196	16%	0.16	C	C	.	.	H	α-helix	trans	-60.9	-35.4	178.6	0	0	0	0	0	113.1	A195 F196 C197 V201 V202 A203	A195-G199 PolarHBondContact O-N 2.83Å; F196-G199 CarbonylContact O-C 3.56Å; F196-G199 PolarHBondContact O-N 3.21Å; F196-G199 VanDerWaalsContact O-N 3.15Å; C197-G199 VanDerWaalsContact C-N 3.32Å; C197-G199 PolarHBondContact O-N 2.93Å; G199-V201 VanDerWaalsContact C-N 3.34Å; G199-V202 PolarHBondContact O-N 3.16Å; G199-A203 WeakPolarHBondContact O-CB 3.33Å; G199-A203 PolarHBondContact O-N 3.11Å
200	T	95.9	Very high	95.3	Very high	12 Å²	12	24.2 Å²	24.2	7%	0.074	15%	0.149	C	C	.	.	H	α-helix	trans	-66.1	-36.7	175.5	67.9	0	0	0	0	112.3	Y165 F196 C197 A198 A204 M399	Y165-T200 HydrophobicContact CE2-CG2 3.89Å; F196-T200 HydrophobicContact CD1-CG2 4.12Å; F196-T200 HydrophobicContact CD2-CG2 4.33Å; F196-T200 HydrophobicContact CE1-CG2 3.84Å; F196-T200 HydrophobicContact CE2-CG2 4.04Å; F196-T200 HydrophobicContact CG-CG2 4.38Å; F196-T200 HydrophobicContact CZ-CG2 3.82Å; F196-T200 WeakPolarHBondContact O-CG2 3.31Å; F196-T200 PolarHBondContact O-N 3.42Å; C197-T200 PolarHBondContact O-N 3.07Å; C197-T200 PolarHBondContact O-OG1 3.49Å; A198-T200 VanDerWaalsContact C-N 3.3Å; A198-T200 PolarHBondContact O-N 2.92Å; T200-A204 WeakPolarHBondContact O-CB 3.48Å; T200-A204 PolarHBondContact O-N 3.38Å; T200-M399 HydrophobicContact CG2-CE 3.48Å; T200-M399 VanDerWaalsContact CG2-CE 3.48Å; T200-M399 HydrophobicContact CG2-SD 3.6Å; T200-M399 VanDerWaalsContact CG2-SD 3.6Å
201	V	96	Very high	94.7	Very high	18 Å²	18	30.3 Å²	30.3	11%	0.109	17%	0.172	C	C	.	.	H	α-helix	trans	-67.3	-47.7	175.3	176.4	0	0	0	0	110.4	T168 H173 C197 A198 G199 A204 K205 V257 T258	T168-V201 HydrophobicContact CG2-CG2 3.62Å; H173-V201 VanDerWaalsContact CE1-CG2 3.42Å; H173-V201 WeakPolarHBondContact CE1-CG2 3.48Å; C197-V201 PolarHBondContact O-N 3.42Å; A198-V201 WeakPolarHBondContact O-CB 3.21Å; A198-V201 PolarHBondContact O-N 2.89Å; A198-V201 VanDerWaalsContact O-N 3.14Å; G199-V201 VanDerWaalsContact C-N 3.34Å; V201-A204 PolarHBondContact O-N 2.83Å; V201-K205 PolarHBondContact O-N 2.87Å; V201-K205 VanDerWaalsContact O-N 3.09Å; V201-V257 HydrophobicContact CG1-CB 4.24Å; V201-V257 HydrophobicContact CG1-CG1 3.54Å; V201-T258 HydrophobicContact CG1-CG2 4.26Å
202	V	96	Very high	94	Very high	26 Å²	26	34.8 Å²	34.8	16%	0.158	19%	0.194	C	C	.	.	H	α-helix	trans	-60.4	-48.2	176.7	176.4	0	0	0	0	110.3	A198 G199 A204 K205 M206 F244 F245 V254 T258	A198-V202 WeakPolarHBondContact O-CG2 3.49Å; A198-V202 PolarHBondContact O-N 2.93Å; G199-V202 PolarHBondContact O-N 3.16Å; V202-A204 VanDerWaalsContact C-N 3.33Å; V202-A204 PolarHBondContact O-N 3.27Å; V202-K205 PolarHBondContact O-N 3.43Å; V202-K205 VanDerWaalsContact O-N 3.12Å; V202-M206 HydrophobicContact CG1-CG 4.24Å; V202-M206 HydrophobicContact CG1-SD 3.97Å; V202-M206 WeakPolarHBondContact O-CG 3.18Å; V202-M206 PolarHBondContact O-N 3.01Å; V202-F244 HydrophobicContact CG1-CE1 4.3Å; V202-F245 HydrophobicContact CG1-CE1 4.24Å; V202-F245 HydrophobicContact CG1-CZ 4.09Å; V202-V254 HydrophobicContact CG2-CG1 3.87Å; V202-T258 HydrophobicContact CG2-CG2 3.97Å
203	A	94.5	Very high	93.1	Very high	3 Å²	3	37.7 Å²	37.7	3%	0.025	21%	0.206	C	C	.	.	H	α-helix	trans	-58.2	-43.1	178.6	0	0	0	0	0	112.2	G199 K205 M206 D207 F398 M399	G199-A203 WeakPolarHBondContact O-CB 3.33Å; G199-A203 PolarHBondContact O-N 3.11Å; A203-K205 VanDerWaalsContact C-N 3.35Å; A203-K205 PolarHBondContact O-N 3.2Å; A203-M206 PolarHBondContact O-N 3.37Å; A203-D207 WeakPolarHBondContact O-CB 3.42Å; A203-D207 PolarHBondContact O-N 2.82Å; A203-F398 HydrophobicContact CB-CB 3.72Å; A203-M399 HydrophobicContact CB-CB 4.44Å
204	A	93.4	Very high	91.8	Very high	48 Å²	48	41 Å²	41	40%	0.397	22%	0.219	S	C	.	.	H	α-helix	trans	-62.1	-41.3	176.4	0	0	0	0	0	112.2	T200 V201 V202 D207 D208	T200-A204 WeakPolarHBondContact O-CB 3.48Å; T200-A204 PolarHBondContact O-N 3.38Å; V201-A204 PolarHBondContact O-N 2.83Å; V202-A204 VanDerWaalsContact C-N 3.33Å; V202-A204 PolarHBondContact O-N 3.27Å; A204-D207 WeakPolarHBondContact O-CB 3.41Å; A204-D207 PolarHBondContact O-N 3.48Å; A204-D208 VanDerWaalsContact O-CG 3.3Å; A204-D208 PolarHBondContact O-N 2.87Å
205	K	93.1	Very high	90.2	Very high	81 Å²	81	45.9 Å²	45.9	35%	0.352	25%	0.249	S	C	.	.	H	α-helix	trans	-67.4	-40.9	175.3	-68.5	-60.9	-176.3	-174.9	0	112.5	V201 V202 A203 D207 D208 V209 F244	V201-K205 PolarHBondContact O-N 2.87Å; V201-K205 VanDerWaalsContact O-N 3.09Å; V202-K205 PolarHBondContact O-N 3.43Å; V202-K205 VanDerWaalsContact O-N 3.12Å; A203-K205 VanDerWaalsContact C-N 3.35Å; A203-K205 PolarHBondContact O-N 3.2Å; K205-D207 VanDerWaalsContact C-N 3.31Å; K205-D207 PolarHBondContact O-N 2.94Å; K205-D208 PolarHBondContact O-N 3.46Å; K205-V209 WeakPolarHBondContact O-CG2 3.36Å; K205-V209 PolarHBondContact O-N 3.47Å; K205-F244 HydrophobicContact CB-CZ 4.13Å
206	M	92.4	Very high	88.4	Confident	13 Å²	13	52 Å²	52	6%	0.064	27%	0.267	C	S	.	.	H	α-helix	trans	-60.3	-43	173.2	-68.3	179.7	83.1	0	0	111	V202 A203 D208 V209 W210 F240 F244 F245 F398	V202-M206 HydrophobicContact CG1-CG 4.24Å; V202-M206 HydrophobicContact CG1-SD 3.97Å; V202-M206 WeakPolarHBondContact O-CG 3.18Å; V202-M206 PolarHBondContact O-N 3.01Å; A203-M206 PolarHBondContact O-N 3.37Å; M206-D208 VanDerWaalsContact C-N 3.34Å; M206-D208 PolarHBondContact O-N 3.05Å; M206-V209 PolarHBondContact O-N 3.05Å; M206-W210 WeakPolarHBondContact O-CB 3.38Å; M206-W210 PolarHBondContact O-N 3.36Å; M206-F240 HydrophobicContact CB-CE1 4.37Å; M206-F240 HydrophobicContact CE-CD1 4.47Å; M206-F240 HydrophobicContact CE-CE1 4.07Å; M206-F244 HydrophobicContact CB-CE2 4.22Å; M206-F244 HydrophobicContact CB-CZ 4.37Å; M206-F244 HydrophobicContact CE-CD1 4.44Å; M206-F244 HydrophobicContact CG-CD1 3.83Å; M206-F244 HydrophobicContact CG-CD2 3.95Å; M206-F244 HydrophobicContact CG-CE1 3.52Å; M206-F244 HydrophobicContact CG-CE2 3.65Å; M206-F244 HydrophobicContact CG-CG 4.04Å; M206-F244 HydrophobicContact CG-CZ 3.43Å; M206-F244 VanDerWaalsContact CG-CZ 3.43Å; M206-F244 HydrophobicContact SD-CD1 4.44Å; M206-F244 HydrophobicContact SD-CE1 4.37Å; M206-F245 HydrophobicContact CE-CE2 4.34Å; M206-F245 HydrophobicContact SD-CZ 4.33Å; M206-F398 HydrophobicContact CB-CB 4.37Å; M206-F398 HydrophobicContact CB-CD1 4.25Å; M206-F398 HydrophobicContact CB-CD2 3.56Å; M206-F398 HydrophobicContact CB-CE1 4.47Å; M206-F398 HydrophobicContact CB-CE2 3.84Å; M206-F398 HydrophobicContact CB-CG 3.81Å; M206-F398 HydrophobicContact CB-CZ 4.3Å; M206-F398 HydrophobicContact CE-CD1 3.61Å; M206-F398 HydrophobicContact CE-CE1 3.45Å; M206-F398 VanDerWaalsContact CE-CE1 3.45Å; M206-F398 HydrophobicContact CE-CG 4.35Å; M206-F398 HydrophobicContact CE-CZ 4.09Å; M206-F398 HydrophobicContact SD-CD1 3.92Å; M206-F398 HydrophobicContact SD-CE1 4.34Å; M206-F398 HydrophobicContact SD-CG 4.2Å
207	D	90.6	Very high	86.5	Confident	26 Å²	26	59.3 Å²	59.3	14%	0.139	30%	0.298	C	S	.	.	H	α-helix	trans	-61.9	-39	175.9	-77.6	-41.3	0	0	0	112.7	A203 A204 K205 R211 S396 F398	A203-D207 WeakPolarHBondContact O-CB 3.42Å; A203-D207 PolarHBondContact O-N 2.82Å; A204-D207 WeakPolarHBondContact O-CB 3.41Å; A204-D207 PolarHBondContact O-N 3.48Å; K205-D207 VanDerWaalsContact C-N 3.31Å; K205-D207 PolarHBondContact O-N 2.94Å; D207-R211 WeakPolarHBondContact O-CB 3.25Å; D207-R211 VanDerWaalsContact O-CG 3.22Å; D207-R211 WeakPolarHBondContact O-CG 3.44Å; D207-R211 PolarHBondContact O-N 3.35Å; D207-R211 PolarHBondContact O-NE 3.33Å; D207-R211 VanDerWaalsContact O-NE 3.1Å; D207-S396 VanDerWaalsContact CG-CB 3.44Å; D207-S396 VanDerWaalsContact OD1-CB 3.22Å; D207-S396 WeakPolarHBondContact OD1-CB 3.31Å; D207-S396 WeakPolarHBondContact OD2-CB 3.28Å; D207-S396 PolarHBondContact OD2-OG 2.9Å; D207-F398 VanDerWaalsContact OD1-CD2 3.26Å; D207-F398 WeakPolarHBondContact OD1-CD2 3.49Å
208	D	90.3	Very high	84.2	Confident	68 Å²	68	66 Å²	66	36%	0.364	33%	0.327	S	S	.	.	H	α-helix	trans	-65.5	-50.6	177.5	-70.5	-17.7	0	0	0	111.4	A204 K205 M206 R211 M212	A204-D208 VanDerWaalsContact O-CG 3.3Å; A204-D208 PolarHBondContact O-N 2.87Å; K205-D208 PolarHBondContact O-N 3.46Å; M206-D208 VanDerWaalsContact C-N 3.34Å; M206-D208 PolarHBondContact O-N 3.05Å; D208-R211 PolarHBondContact O-N 2.88Å; D208-R211 IonicContact OD1-CZ 3.8Å; D208-R211 IonicContact OD1-NH2 3.27Å; D208-R211 PolarHBondContact OD1-NH2 3.49Å; D208-M212 WeakPolarHBondContact O-CG 3.36Å; D208-M212 PolarHBondContact O-N 3.1Å
209	V	90.2	Very high	81.7	Confident	54 Å²	54	72.8 Å²	72.8	33%	0.327	36%	0.361	S	S	.	.	H	α-helix	trans	-64.5	-44.7	179.3	179.8	0	0	0	0	110.9	K205 M206 R211 M212 E213 F240 F244	K205-V209 WeakPolarHBondContact O-CG2 3.36Å; K205-V209 PolarHBondContact O-N 3.47Å; M206-V209 PolarHBondContact O-N 3.05Å; V209-R211 VanDerWaalsContact C-N 3.31Å; V209-R211 PolarHBondContact O-N 3.46Å; V209-M212 PolarHBondContact O-N 2.91Å; V209-M212 VanDerWaalsContact O-N 3.16Å; V209-E213 PolarHBondContact O-N 2.85Å; V209-F240 HydrophobicContact CB-CE2 4.44Å; V209-F240 HydrophobicContact CB-CZ 4.25Å; V209-F240 HydrophobicContact CG1-CE2 3.94Å; V209-F240 HydrophobicContact CG1-CZ 4.21Å; V209-F244 HydrophobicContact CB-CD2 4.43Å; V209-F244 HydrophobicContact CB-CE2 4.42Å; V209-F244 HydrophobicContact CG2-CD2 4.42Å; V209-F244 HydrophobicContact CG2-CE2 4.06Å
210	W	87.6	Confident	79.2	Confident	12 Å²	12	79.5 Å²	79.5	5%	0.045	39%	0.387	C	S	.	.	H	α-helix	trans	-58.9	-42.7	177.1	-177.6	-91	0	0	0	111.3	M206 Y214 V227 V237 F240 F398	M206-W210 WeakPolarHBondContact O-CB 3.38Å; M206-W210 PolarHBondContact O-N 3.36Å; W210-Y214 HydrophobicContact CD2-CD2 4.05Å; W210-Y214 AromaticContact CD2-CE2 3.7Å; W210-Y214 HydrophobicContact CD2-CE2 3.7Å; W210-Y214 AromaticContact CE2-CD2 3.82Å; W210-Y214 AromaticContact CE2-CE2 3.29Å; W210-Y214 AromaticContact CE2-CZ 3.91Å; W210-Y214 AromaticContact CE3-CE2 3.99Å; W210-Y214 HydrophobicContact CE3-CE2 3.99Å; W210-Y214 HydrophobicContact CG-CD2 4.28Å; W210-Y214 HydrophobicContact CG-CE2 4.4Å; W210-Y214 AromaticContact CH2-CE2 3.64Å; W210-Y214 HydrophobicContact CH2-CE2 3.64Å; W210-Y214 AromaticContact CH2-CZ 3.88Å; W210-Y214 WeakPolarHBondContact CH2-OH 3.44Å; W210-Y214 HydrophobicContact CZ2-CD2 4.24Å; W210-Y214 AromaticContact CZ2-CE2 3.28Å; W210-Y214 HydrophobicContact CZ2-CE2 3.28Å; W210-Y214 AromaticContact CZ2-CZ 3.47Å; W210-Y214 VanDerWaalsContact CZ2-CZ 3.47Å; W210-Y214 VanDerWaalsContact CZ2-OH 3.27Å; W210-Y214 WeakPolarHBondContact CZ2-OH 3.43Å; W210-Y214 AromaticContact CZ3-CE2 3.97Å; W210-Y214 HydrophobicContact CZ3-CE2 3.97Å; W210-Y214 AromaticContact NE1-CD2 3.84Å; W210-Y214 AromaticContact NE1-CE2 3.76Å; W210-Y214 VanDerWaalsContact O-CD2 3.25Å; W210-Y214 WeakPolarHBondContact O-CD2 3.33Å; W210-Y214 PolarHBondContact O-N 3.26Å; W210-V227 HydrophobicContact CZ2-CG2 3.98Å; W210-V237 HydrophobicContact CH2-CG2 3.7Å; W210-V237 HydrophobicContact CZ2-CG2 4.27Å; W210-V237 HydrophobicContact CZ3-CG2 4.25Å; W210-F240 HydrophobicContact CB-CE1 4.24Å; W210-F240 HydrophobicContact CB-CE2 4.16Å; W210-F240 HydrophobicContact CB-CZ 3.75Å; W210-F240 HydrophobicContact CE3-CB 3.89Å; W210-F240 AromaticContact CE3-CD1 3.38Å; W210-F240 HydrophobicContact CE3-CD1 3.38Å; W210-F240 AromaticContact CE3-CD2 3.52Å; W210-F240 HydrophobicContact CE3-CD2 3.52Å; W210-F240 AromaticContact CE3-CE1 3.7Å; W210-F240 HydrophobicContact CE3-CE1 3.7Å; W210-F240 AromaticContact CE3-CE2 3.81Å; W210-F240 HydrophobicContact CE3-CE2 3.81Å; W210-F240 AromaticContact CE3-CG 3.29Å; W210-F240 HydrophobicContact CE3-CG 3.29Å; W210-F240 AromaticContact CE3-CZ 3.9Å; W210-F240 HydrophobicContact CE3-CZ 3.9Å; W210-F240 HydrophobicContact CZ3-CB 3.45Å; W210-F240 VanDerWaalsContact CZ3-CB 3.45Å; W210-F240 AromaticContact CZ3-CD1 3.75Å; W210-F240 HydrophobicContact CZ3-CD1 3.75Å; W210-F240 AromaticContact CZ3-CD2 3.98Å; W210-F240 HydrophobicContact CZ3-CD2 3.98Å; W210-F240 HydrophobicContact CZ3-CE1 4.49Å; W210-F240 AromaticContact CZ3-CG 3.44Å; W210-F240 HydrophobicContact CZ3-CG 3.44Å; W210-F240 VanDerWaalsContact CZ3-CG 3.44Å; W210-F398 HydrophobicContact CB-CE2 3.99Å; W210-F398 HydrophobicContact CD2-CE2 4.37Å; W210-F398 HydrophobicContact CD2-CZ 4.3Å; W210-F398 HydrophobicContact CE3-CZ 4.17Å; W210-F398 HydrophobicContact CG-CE2 4.12Å
211	R	85.5	Confident	76.5	Confident	130 Å²	130	89 Å²	89	49%	0.491	42%	0.422	S	S	.	.	H	α-helix	trans	-62.8	-44.9	175.2	-79	-179	-72.5	-159.2	2.8	112	D207 D208 V209 E213 Y214 T215	D207-R211 WeakPolarHBondContact O-CB 3.25Å; D207-R211 VanDerWaalsContact O-CG 3.22Å; D207-R211 WeakPolarHBondContact O-CG 3.44Å; D207-R211 PolarHBondContact O-N 3.35Å; D207-R211 PolarHBondContact O-NE 3.33Å; D207-R211 VanDerWaalsContact O-NE 3.1Å; D208-R211 PolarHBondContact O-N 2.88Å; D208-R211 IonicContact OD1-CZ 3.8Å; D208-R211 IonicContact OD1-NH2 3.27Å; D208-R211 PolarHBondContact OD1-NH2 3.49Å; V209-R211 VanDerWaalsContact C-N 3.31Å; V209-R211 PolarHBondContact O-N 3.46Å; R211-E213 PolarHBondContact O-N 3.41Å; R211-Y214 PolarHBondContact O-N 2.9Å; R211-T215 WeakPolarHBondContact O-CB 3.31Å; R211-T215 PolarHBondContact O-N 3.28Å; R211-T215 PolarHBondContact O-OG1 2.99Å
212	M	84.3	Confident	73.8	Confident	122 Å²	122	95.7 Å²	95.7	60%	0.601	46%	0.456	S	S	*	.	H	α-helix	trans	-61.2	-42.3	179.7	-71.3	179.8	65.1	0	0	112.8	D208 V209 Y214 K216	D208-M212 WeakPolarHBondContact O-CG 3.36Å; D208-M212 PolarHBondContact O-N 3.1Å; V209-M212 PolarHBondContact O-N 2.91Å; V209-M212 VanDerWaalsContact O-N 3.16Å; M212-Y214 VanDerWaalsContact C-N 3.32Å; M212-Y214 PolarHBondContact O-N 3.44Å; M212-K216 WeakPolarHBondContact O-CG 3.43Å; M212-K216 PolarHBondContact O-N 2.77Å; M212-K216 VanDerWaalsContact O-N 3.16Å
213	E	79.6	Confident	70.9	Confident	78 Å²	78	99.3 Å²	99.3	36%	0.364	48%	0.483	S	S	.	.	H	α-helix	trans	-66.2	-36.8	179.8	-155.4	-163.2	146.7	0	0	112.1	V209 R211 K217	V209-E213 PolarHBondContact O-N 2.85Å; R211-E213 PolarHBondContact O-N 3.41Å; E213-K217 IonicContact OE1-NZ 2.82Å; E213-K217 PolarHBondContact OE1-NZ 3.34Å
214	Y	70	Confident	68.4	Low	76 Å²	76	102.9 Å²	102.9	30%	0.298	51%	0.512	S	S	.	.	H	α-helix	trans	-79.9	-32.7	179.1	-85	-96.4	0	0	0	113.5	W210 R211 M212 K217 K218	W210-Y214 HydrophobicContact CD2-CD2 4.05Å; W210-Y214 AromaticContact CD2-CE2 3.7Å; W210-Y214 HydrophobicContact CD2-CE2 3.7Å; W210-Y214 AromaticContact CE2-CD2 3.82Å; W210-Y214 AromaticContact CE2-CE2 3.29Å; W210-Y214 AromaticContact CE2-CZ 3.91Å; W210-Y214 AromaticContact CE3-CE2 3.99Å; W210-Y214 HydrophobicContact CE3-CE2 3.99Å; W210-Y214 HydrophobicContact CG-CD2 4.28Å; W210-Y214 HydrophobicContact CG-CE2 4.4Å; W210-Y214 AromaticContact CH2-CE2 3.64Å; W210-Y214 HydrophobicContact CH2-CE2 3.64Å; W210-Y214 AromaticContact CH2-CZ 3.88Å; W210-Y214 WeakPolarHBondContact CH2-OH 3.44Å; W210-Y214 HydrophobicContact CZ2-CD2 4.24Å; W210-Y214 AromaticContact CZ2-CE2 3.28Å; W210-Y214 HydrophobicContact CZ2-CE2 3.28Å; W210-Y214 AromaticContact CZ2-CZ 3.47Å; W210-Y214 VanDerWaalsContact CZ2-CZ 3.47Å; W210-Y214 VanDerWaalsContact CZ2-OH 3.27Å; W210-Y214 WeakPolarHBondContact CZ2-OH 3.43Å; W210-Y214 AromaticContact CZ3-CE2 3.97Å; W210-Y214 HydrophobicContact CZ3-CE2 3.97Å; W210-Y214 AromaticContact NE1-CD2 3.84Å; W210-Y214 AromaticContact NE1-CE2 3.76Å; W210-Y214 VanDerWaalsContact O-CD2 3.25Å; W210-Y214 WeakPolarHBondContact O-CD2 3.33Å; W210-Y214 PolarHBondContact O-N 3.26Å; R211-Y214 PolarHBondContact O-N 2.9Å; M212-Y214 VanDerWaalsContact C-N 3.32Å; M212-Y214 PolarHBondContact O-N 3.44Å; Y214-K217 PolarHBondContact O-N 3.16Å; Y214-K218 PolarHBondContact O-N 3.21Å
215	T	64.8	Low	66.3	Low	109 Å²	109	104.4 Å²	104.4	67%	0.669	52%	0.517	S	S	*	.	H	α-helix	trans	-67.5	-35.9	173.5	-59.8	0	0	0	0	111.5	R211 K217	R211-T215 WeakPolarHBondContact O-CB 3.31Å; R211-T215 PolarHBondContact O-N 3.28Å; R211-T215 PolarHBondContact O-OG1 2.99Å; T215-K217 PolarHBondContact O-N 3.02Å
216	K	60	Low	64.5	Low	180 Å²	180	110.6 Å²	110.6	78%	0.783	54%	0.537	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.2	-19.2	174.2	-76.6	-176	177.9	-175.7	0	114	M212	M212-K216 WeakPolarHBondContact O-CG 3.43Å; M212-K216 PolarHBondContact O-N 2.77Å; M212-K216 VanDerWaalsContact O-N 3.16Å
217	K	59.2	Low	62.7	Low	153 Å²	153	111.3 Å²	111.3	67%	0.665	54%	0.543	S	S	*	.	T	Hydrogen-bonded Turn	trans	-102.7	-3.1	-174.4	-78.8	175.4	177.9	163.7	0	114.5	E213 Y214 T215	E213-K217 IonicContact OE1-NZ 2.82Å; E213-K217 PolarHBondContact OE1-NZ 3.34Å; Y214-K217 PolarHBondContact O-N 3.16Å; T215-K217 PolarHBondContact O-N 3.02Å
218	K	50.7	Low	60.9	Low	142 Å²	142	113.5 Å²	113.5	62%	0.617	56%	0.558	S	S	*	*			trans	-148.3	101.9	-174.9	-145.5	-173.8	-179.2	-156.4	0	114.3	Y214 R221	Y214-K218 PolarHBondContact O-N 3.21Å; K218-R221 PolarHBondContact NZ-O 2.83Å
219	D	44.5	Very low	59.3	Low	158 Å²	158	118.2 Å²	118.2	85%	0.845	58%	0.582	S	S	*	*			trans	-66.6	136	150.4	-112.5	-27.7	0	0	0	109.1
220	E	45	Very low	58.3	Low	160 Å²	160	118.3 Å²	118.3	75%	0.748	59%	0.586	S	S	*	*	S	Bend	trans	60.2	123.4	170.5	-57.4	-163.2	156.6	0	0	121.3
221	R	39.4	Very low	57.5	Low	211 Å²	211	122.2 Å²	122.2	80%	0.796	62%	0.615	S	S	*	*			trans	80.7	118.2	157.4	-71.6	178.6	173.3	-178.1	-1.2	120.1	K218	K218-R221 PolarHBondContact NZ-O 2.83Å
222	L	38.7	Very low	57	Low	160 Å²	160	122.7 Å²	122.7	84%	0.838	62%	0.622	S	S	*	*			trans	99.5	102.2	159.6	-76.8	129.1	0	0	0	118.8
223	S	35.9	Very low	56.7	Low	102 Å²	102	117 Å²	117	71%	0.713	60%	0.595	S	S	*	*	S	Bend	trans	-32	140.6	158.8	30	0	0	0	0	117
224	A	41.2	Very low	56.7	Low	77 Å²	77	116.5 Å²	116.5	64%	0.636	60%	0.597	S	S	*	*	S	Bend	trans	64.5	99.3	176	0	0	0	0	0	114.2	R226	A224-R226 VanDerWaalsContact C-N 3.26Å; A224-R226 PolarHBondContact O-N 2.81Å
225	V	49.2	Very low	57.4	Low	81 Å²	81	120 Å²	120	49%	0.491	61%	0.614	S	S	.	*			trans	-55.1	88	169.7	-176	0	0	0	0	109.4
226	R	54.7	Low	58.3	Low	210 Å²	210	120.7 Å²	120.7	79%	0.792	61%	0.608	S	S	*	*			trans	-90.3	116.4	172.3	-82.3	-175.3	-92.1	-161.2	-5.1	107.1	A224 P228	A224-R226 VanDerWaalsContact C-N 3.26Å; A224-R226 PolarHBondContact O-N 2.81Å; R226-P228 WeakPolarHBondContact O-CD 3.36Å; R226-P228 VanDerWaalsContact O-N 3.17Å
227	V	55.2	Low	59.6	Low	28 Å²	28	112.9 Å²	112.9	17%	0.17	58%	0.575	C	S	.	*			trans	-59.2	114.9	165.5	174.2	0	0	0	0	107.2	W210 L229 V237 F397	W210-V227 HydrophobicContact CZ2-CG2 3.98Å; V227-L229 PolarHBondContact O-N 3.47Å; V227-V237 HydrophobicContact CB-CG2 4.23Å; V227-V237 HydrophobicContact CG1-CG2 3.35Å; V227-V237 HydrophobicContact CG2-CG2 3.81Å; V227-F397 HydrophobicContact CG2-CB 4.19Å; V227-F397 HydrophobicContact CG2-CD1 4.29Å; V227-F397 HydrophobicContact CG2-CG 4.08Å
228	P	53.5	Low	60.9	Low	72 Å²	72	110 Å²	110	47%	0.468	57%	0.566	S	S	.	*			trans	-69.3	128.8	174	25.1	-25.9	0	0	0	108.6	R226 S230 G233	R226-P228 WeakPolarHBondContact O-CD 3.36Å; R226-P228 VanDerWaalsContact O-N 3.17Å; P228-S230 PolarHBondContact O-N 3.44Å; P228-G233 VanDerWaalsContact O-CA 3.32Å; P228-G233 WeakPolarHBondContact O-CA 3.35Å
229	L	55.8	Low	62.7	Low	167 Å²	167	107 Å²	107	87%	0.874	56%	0.559	S	S	*	*			trans	-69.4	16.5	171.2	-85	131.8	0	0	0	113.1	V227	V227-L229 PolarHBondContact O-N 3.47Å
230	S	69	Low	64.9	Low	57 Å²	57	100 Å²	100	40%	0.399	52%	0.522	S	S	.	.	S	Bend	trans	-70.6	155.6	170.9	66.7	0	0	0	0	109.9	P228 Q232 G233 V234	P228-S230 PolarHBondContact O-N 3.44Å; S230-Q232 PolarHBondContact O-N 3.34Å; S230-Q232 VanDerWaalsContact O-N 3.12Å; S230-G233 WeakPolarHBondContact O-CA 3.45Å; S230-G233 PolarHBondContact O-N 3.35Å; S230-G233 PolarHBondContact OG-N 2.9Å; S230-V234 PolarHBondContact O-N 3.46Å
231	S	70.9	Confident	67	Low	93 Å²	93	93.6 Å²	93.6	65%	0.65	50%	0.495	S	S	*	.	H	α-helix	trans	-52.7	-36	177.1	56.1	0	0	0	0	112.6	K235	S231-K235 WeakPolarHBondContact O-CG 3.05Å; S231-K235 PolarHBondContact O-N 3.04Å; S231-K235 VanDerWaalsContact O-N 3.09Å
232	Q	74.4	Confident	69.5	Low	140 Å²	140	88.6 Å²	88.6	65%	0.654	48%	0.483	S	S	*	.	H	α-helix	trans	-69.3	-38.4	174.1	-68.9	-178.8	-9.1	0	0	113.2	S230 K236	S230-Q232 PolarHBondContact O-N 3.34Å; S230-Q232 VanDerWaalsContact O-N 3.12Å; Q232-K236 WeakPolarHBondContact O-CG 3.07Å; Q232-K236 PolarHBondContact O-N 3.4Å
233	G	78.2	Confident	71.9	Confident	2 Å²	2	85.4 Å²	85.4	2%	0.021	47%	0.467	C	S	.	.	H	α-helix	trans	-70.5	-37.7	176.6	0	0	0	0	0	112.9	P228 S230 K236 V237	P228-G233 VanDerWaalsContact O-CA 3.32Å; P228-G233 WeakPolarHBondContact O-CA 3.35Å; S230-G233 WeakPolarHBondContact O-CA 3.45Å; S230-G233 PolarHBondContact O-N 3.35Å; S230-G233 PolarHBondContact OG-N 2.9Å; G233-K236 PolarHBondContact O-N 2.72Å; G233-V237 PolarHBondContact O-N 2.75Å
234	V	80.6	Confident	74.5	Confident	69 Å²	69	80.9 Å²	80.9	42%	0.418	43%	0.434	S	S	.	.	H	α-helix	trans	-61.9	-48.1	172.7	175.7	0	0	0	0	110.7	S230 K236 V237 I238	S230-V234 PolarHBondContact O-N 3.46Å; V234-K236 VanDerWaalsContact C-N 3.32Å; V234-K236 PolarHBondContact O-N 3.24Å; V234-V237 PolarHBondContact O-N 2.99Å; V234-I238 HydrophobicContact CG1-CD1 3.82Å; V234-I238 HydrophobicContact CG1-CG1 4.45Å; V234-I238 WeakPolarHBondContact O-CG1 3.49Å; V234-I238 PolarHBondContact O-N 3.48Å
235	K	84.1	Confident	76.9	Confident	149 Å²	149	82.7 Å²	82.7	65%	0.648	43%	0.428	S	S	*	.	H	α-helix	trans	-56	-46.1	174.8	-76.7	-177.3	178.9	-171.9	0	111.8	S231 V237 I238 T239	S231-K235 WeakPolarHBondContact O-CG 3.05Å; S231-K235 PolarHBondContact O-N 3.04Å; S231-K235 VanDerWaalsContact O-N 3.09Å; K235-V237 PolarHBondContact O-N 3.18Å; K235-I238 PolarHBondContact O-N 3.36Å; K235-T239 PolarHBondContact O-N 3.2Å; K235-T239 PolarHBondContact O-OG1 3.42Å; K235-T239 VanDerWaalsContact O-OG1 3.08Å
236	K	84.3	Confident	78.9	Confident	124 Å²	124	83.6 Å²	83.6	54%	0.539	43%	0.434	S	S	.	.	H	α-helix	trans	-59.1	-43.6	177.5	-77.2	179.9	180	-175.2	0	113	Q232 G233 V234 F240	Q232-K236 WeakPolarHBondContact O-CG 3.07Å; Q232-K236 PolarHBondContact O-N 3.4Å; G233-K236 PolarHBondContact O-N 2.72Å; V234-K236 VanDerWaalsContact C-N 3.32Å; V234-K236 PolarHBondContact O-N 3.24Å; K236-F240 WeakPolarHBondContact O-CB 3.41Å; K236-F240 PolarHBondContact O-N 2.92Å
237	V	86.4	Confident	80.7	Confident	15 Å²	15	75.5 Å²	75.5	9%	0.091	41%	0.409	C	S	.	.	H	α-helix	trans	-66.2	-39.8	177.1	168.6	0	0	0	0	111.8	W210 V227 G233 V234 K235 S241 F397 F398	W210-V237 HydrophobicContact CH2-CG2 3.7Å; W210-V237 HydrophobicContact CZ2-CG2 4.27Å; W210-V237 HydrophobicContact CZ3-CG2 4.25Å; V227-V237 HydrophobicContact CB-CG2 4.23Å; V227-V237 HydrophobicContact CG1-CG2 3.35Å; V227-V237 HydrophobicContact CG2-CG2 3.81Å; G233-V237 PolarHBondContact O-N 2.75Å; V234-V237 PolarHBondContact O-N 2.99Å; K235-V237 PolarHBondContact O-N 3.18Å; V237-S241 VanDerWaalsContact O-CB 3.28Å; V237-S241 WeakPolarHBondContact O-CB 3.43Å; V237-S241 PolarHBondContact O-N 2.94Å; V237-S241 PolarHBondContact O-OG 2.9Å; V237-F397 HydrophobicContact CG1-CE1 3.69Å; V237-F397 HydrophobicContact CG1-CZ 4.21Å; V237-F398 HydrophobicContact CG1-CE1 4.44Å
238	I	87.2	Confident	82.4	Confident	93 Å²	93	79.2 Å²	79.2	48%	0.477	43%	0.434	S	S	.	.	H	α-helix	trans	-63.3	-51.3	177	-68.3	168.9	0	0	0	110.1	V234 K235 F240 S241 L242	V234-I238 HydrophobicContact CG1-CD1 3.82Å; V234-I238 HydrophobicContact CG1-CG1 4.45Å; V234-I238 WeakPolarHBondContact O-CG1 3.49Å; V234-I238 PolarHBondContact O-N 3.48Å; K235-I238 PolarHBondContact O-N 3.36Å; I238-F240 PolarHBondContact O-N 3.26Å; I238-S241 PolarHBondContact O-N 3.32Å; I238-S241 VanDerWaalsContact O-N 3.15Å; I238-L242 HydrophobicContact CG2-CD1 3.99Å; I238-L242 HydrophobicContact CG2-CG 4.47Å; I238-L242 WeakPolarHBondContact O-CG 3.36Å; I238-L242 PolarHBondContact O-N 2.91Å
239	T	88.4	Confident	84	Confident	78 Å²	78	83.4 Å²	83.4	48%	0.479	45%	0.448	S	S	.	.	H	α-helix	trans	-57.5	-50.1	178.5	-56.2	0	0	0	0	111.1	K235 S241 L242 D243	K235-T239 PolarHBondContact O-N 3.2Å; K235-T239 PolarHBondContact O-OG1 3.42Å; K235-T239 VanDerWaalsContact O-OG1 3.08Å; T239-S241 VanDerWaalsContact C-N 3.32Å; T239-S241 PolarHBondContact O-N 2.69Å; T239-L242 PolarHBondContact O-N 3.29Å; T239-D243 VanDerWaalsContact O-CG 3.23Å; T239-D243 PolarHBondContact O-N 3.07Å
240	F	90.6	Very high	85.6	Confident	12 Å²	12	76.8 Å²	76.8	5%	0.053	41%	0.414	C	S	.	.	H	α-helix	trans	-58.3	-42	175.6	169.1	-94.4	0	0	0	113.2	M206 V209 W210 K236 I238 L242 D243 F244 F398	M206-F240 HydrophobicContact CB-CE1 4.37Å; M206-F240 HydrophobicContact CE-CD1 4.47Å; M206-F240 HydrophobicContact CE-CE1 4.07Å; V209-F240 HydrophobicContact CB-CE2 4.44Å; V209-F240 HydrophobicContact CB-CZ 4.25Å; V209-F240 HydrophobicContact CG1-CE2 3.94Å; V209-F240 HydrophobicContact CG1-CZ 4.21Å; W210-F240 HydrophobicContact CB-CE1 4.24Å; W210-F240 HydrophobicContact CB-CE2 4.16Å; W210-F240 HydrophobicContact CB-CZ 3.75Å; W210-F240 HydrophobicContact CE3-CB 3.89Å; W210-F240 AromaticContact CE3-CD1 3.38Å; W210-F240 HydrophobicContact CE3-CD1 3.38Å; W210-F240 AromaticContact CE3-CD2 3.52Å; W210-F240 HydrophobicContact CE3-CD2 3.52Å; W210-F240 AromaticContact CE3-CE1 3.7Å; W210-F240 HydrophobicContact CE3-CE1 3.7Å; W210-F240 AromaticContact CE3-CE2 3.81Å; W210-F240 HydrophobicContact CE3-CE2 3.81Å; W210-F240 AromaticContact CE3-CG 3.29Å; W210-F240 HydrophobicContact CE3-CG 3.29Å; W210-F240 AromaticContact CE3-CZ 3.9Å; W210-F240 HydrophobicContact CE3-CZ 3.9Å; W210-F240 HydrophobicContact CZ3-CB 3.45Å; W210-F240 VanDerWaalsContact CZ3-CB 3.45Å; W210-F240 AromaticContact CZ3-CD1 3.75Å; W210-F240 HydrophobicContact CZ3-CD1 3.75Å; W210-F240 AromaticContact CZ3-CD2 3.98Å; W210-F240 HydrophobicContact CZ3-CD2 3.98Å; W210-F240 HydrophobicContact CZ3-CE1 4.49Å; W210-F240 AromaticContact CZ3-CG 3.44Å; W210-F240 HydrophobicContact CZ3-CG 3.44Å; W210-F240 VanDerWaalsContact CZ3-CG 3.44Å; K236-F240 WeakPolarHBondContact O-CB 3.41Å; K236-F240 PolarHBondContact O-N 2.92Å; I238-F240 PolarHBondContact O-N 3.26Å; F240-L242 VanDerWaalsContact C-N 3.32Å; F240-L242 PolarHBondContact O-N 3.49Å; F240-D243 PolarHBondContact O-N 3.39Å; F240-F244 HydrophobicContact CE1-CB 4.43Å; F240-F244 HydrophobicContact CE1-CD2 4.49Å; F240-F244 HydrophobicContact CZ-CD2 4.17Å; F240-F244 VanDerWaalsContact O-CB 3.23Å; F240-F244 WeakPolarHBondContact O-CB 3.33Å; F240-F244 PolarHBondContact O-N 3Å; F240-F398 HydrophobicContact CD1-CE1 4.46Å; F240-F398 AromaticContact CD1-CZ 3.88Å; F240-F398 HydrophobicContact CD1-CZ 3.88Å; F240-F398 HydrophobicContact CE1-CE1 4.3Å; F240-F398 HydrophobicContact CE1-CE2 4.09Å; F240-F398 AromaticContact CE1-CZ 3.57Å; F240-F398 HydrophobicContact CE1-CZ 3.57Å
241	S	89.9	Confident	86.6	Confident	26 Å²	26	75.9 Å²	75.9	18%	0.182	41%	0.406	C	S	.	.	H	α-helix	trans	-65.5	-40.2	-179.5	-58	0	0	0	0	110.6	V237 I238 T239 F244 F245	V237-S241 VanDerWaalsContact O-CB 3.28Å; V237-S241 WeakPolarHBondContact O-CB 3.43Å; V237-S241 PolarHBondContact O-N 2.94Å; V237-S241 PolarHBondContact O-OG 2.9Å; I238-S241 PolarHBondContact O-N 3.32Å; I238-S241 VanDerWaalsContact O-N 3.15Å; T239-S241 VanDerWaalsContact C-N 3.32Å; T239-S241 PolarHBondContact O-N 2.69Å; S241-F244 PolarHBondContact O-N 3.32Å; S241-F245 WeakPolarHBondContact O-CD2 3.45Å; S241-F245 PolarHBondContact O-N 2.92Å; S241-F245 VanDerWaalsContact O-N 3.09Å
242	L	90.6	Very high	87.6	Confident	106 Å²	106	78 Å²	78	56%	0.555	40%	0.403	S	S	*	.	H	α-helix	trans	-62.9	-46.1	173.5	-68.8	171.1	0	0	0	111.1	I238 T239 F240 F244 F245 T246	I238-L242 HydrophobicContact CG2-CD1 3.99Å; I238-L242 HydrophobicContact CG2-CG 4.47Å; I238-L242 WeakPolarHBondContact O-CG 3.36Å; I238-L242 PolarHBondContact O-N 2.91Å; T239-L242 PolarHBondContact O-N 3.29Å; F240-L242 VanDerWaalsContact C-N 3.32Å; F240-L242 PolarHBondContact O-N 3.49Å; L242-F244 VanDerWaalsContact C-N 3.33Å; L242-F244 PolarHBondContact O-N 2.86Å; L242-F245 PolarHBondContact O-N 3.43Å; L242-T246 WeakPolarHBondContact O-CB 3.37Å; L242-T246 VanDerWaalsContact O-CG2 3.29Å; L242-T246 WeakPolarHBondContact O-CG2 3.47Å; L242-T246 PolarHBondContact O-N 3.32Å; L242-T246 PolarHBondContact O-OG1 3.46Å
243	D	90.1	Very high	88.4	Confident	92 Å²	92	74.3 Å²	74.3	49%	0.492	39%	0.391	S	S	.	.	H	α-helix	trans	-62.5	-41.3	177.9	-64.4	-19.2	0	0	0	111.2	T239 F240 F245 T246 S247	T239-D243 VanDerWaalsContact O-CG 3.23Å; T239-D243 PolarHBondContact O-N 3.07Å; F240-D243 PolarHBondContact O-N 3.39Å; D243-F245 PolarHBondContact O-N 3.27Å; D243-T246 WeakPolarHBondContact CA-OG1 3.41Å; D243-T246 PolarHBondContact O-N 3.34Å; D243-T246 PolarHBondContact O-OG1 3.05Å; D243-S247 VanDerWaalsContact O-CB 3.28Å; D243-S247 WeakPolarHBondContact O-CB 3.21Å; D243-S247 PolarHBondContact O-N 2.92Å
244	F	90.5	Very high	89.1	Confident	8 Å²	8	75 Å²	75	4%	0.035	40%	0.395	C	S	.	.	H	α-helix	trans	-60.8	-42.1	177.2	-178.5	-85.6	0	0	0	112.2	V202 K205 M206 V209 F240 S241 L242 T250 V254	V202-F244 HydrophobicContact CG1-CE1 4.3Å; K205-F244 HydrophobicContact CB-CZ 4.13Å; M206-F244 HydrophobicContact CB-CE2 4.22Å; M206-F244 HydrophobicContact CB-CZ 4.37Å; M206-F244 HydrophobicContact CE-CD1 4.44Å; M206-F244 HydrophobicContact CG-CD1 3.83Å; M206-F244 HydrophobicContact CG-CD2 3.95Å; M206-F244 HydrophobicContact CG-CE1 3.52Å; M206-F244 HydrophobicContact CG-CE2 3.65Å; M206-F244 HydrophobicContact CG-CG 4.04Å; M206-F244 HydrophobicContact CG-CZ 3.43Å; M206-F244 VanDerWaalsContact CG-CZ 3.43Å; M206-F244 HydrophobicContact SD-CD1 4.44Å; M206-F244 HydrophobicContact SD-CE1 4.37Å; V209-F244 HydrophobicContact CB-CD2 4.43Å; V209-F244 HydrophobicContact CB-CE2 4.42Å; V209-F244 HydrophobicContact CG2-CD2 4.42Å; V209-F244 HydrophobicContact CG2-CE2 4.06Å; F240-F244 HydrophobicContact CE1-CB 4.43Å; F240-F244 HydrophobicContact CE1-CD2 4.49Å; F240-F244 HydrophobicContact CZ-CD2 4.17Å; F240-F244 VanDerWaalsContact O-CB 3.23Å; F240-F244 WeakPolarHBondContact O-CB 3.33Å; F240-F244 PolarHBondContact O-N 3Å; S241-F244 PolarHBondContact O-N 3.32Å; L242-F244 VanDerWaalsContact C-N 3.33Å; L242-F244 PolarHBondContact O-N 2.86Å; F244-T250 HydrophobicContact CD1-CG2 4.09Å; F244-T250 HydrophobicContact CD2-CG2 3.53Å; F244-T250 HydrophobicContact CE1-CG2 3.87Å; F244-T250 HydrophobicContact CE2-CG2 3.28Å; F244-T250 HydrophobicContact CG-CG2 3.92Å; F244-T250 HydrophobicContact CZ-CG2 3.45Å; F244-T250 VanDerWaalsContact CZ-CG2 3.45Å; F244-V254 HydrophobicContact CE1-CG2 4Å; F244-V254 HydrophobicContact CZ-CG2 3.85Å
245	F	90.7	Very high	89.7	Confident	114 Å²	114	77.4 Å²	77.4	50%	0.5	40%	0.403	S	S	.	.	H	α-helix	trans	-85.3	-10.8	-179.9	-71.3	-61.4	0	0	0	114.4	V202 M206 S241 L242 D243 V251	V202-F245 HydrophobicContact CG1-CE1 4.24Å; V202-F245 HydrophobicContact CG1-CZ 4.09Å; M206-F245 HydrophobicContact CE-CE2 4.34Å; M206-F245 HydrophobicContact SD-CZ 4.33Å; S241-F245 WeakPolarHBondContact O-CD2 3.45Å; S241-F245 PolarHBondContact O-N 2.92Å; S241-F245 VanDerWaalsContact O-N 3.09Å; L242-F245 PolarHBondContact O-N 3.43Å; D243-F245 PolarHBondContact O-N 3.27Å; F245-V251 WeakPolarHBondContact O-CG2 3.41Å
246	T	91.4	Very high	90.1	Very high	101 Å²	101	76.2 Å²	76.2	62%	0.62	40%	0.399	S	S	*	.	H	α-helix	trans	-100.8	-22.8	175.4	52.6	0	0	0	0	113	L242 D243 P248	L242-T246 WeakPolarHBondContact O-CB 3.37Å; L242-T246 VanDerWaalsContact O-CG2 3.29Å; L242-T246 WeakPolarHBondContact O-CG2 3.47Å; L242-T246 PolarHBondContact O-N 3.32Å; L242-T246 PolarHBondContact O-OG1 3.46Å; D243-T246 WeakPolarHBondContact CA-OG1 3.41Å; D243-T246 PolarHBondContact O-N 3.34Å; D243-T246 PolarHBondContact O-OG1 3.05Å; T246-P248 VanDerWaalsContact O-CD 3.29Å; T246-P248 WeakPolarHBondContact O-CD 3.36Å
247	S	91.9	Very high	90.5	Very high	39 Å²	39	72.1 Å²	72.1	27%	0.273	38%	0.384	S	S	.	.			trans	-62.8	115.9	176.2	176.3	0	0	0	0	111.9	D243 E249 T250 V251	D243-S247 VanDerWaalsContact O-CB 3.28Å; D243-S247 WeakPolarHBondContact O-CB 3.21Å; D243-S247 PolarHBondContact O-N 2.92Å; S247-E249 VanDerWaalsContact C-N 3.31Å; S247-E249 PolarHBondContact O-N 3.2Å; S247-T250 PolarHBondContact O-N 3.4Å; S247-T250 PolarHBondContact OG-OG1 3.41Å; S247-V251 WeakPolarHBondContact O-CB 3.26Å; S247-V251 VanDerWaalsContact O-CG2 3.26Å; S247-V251 WeakPolarHBondContact O-CG2 3.37Å; S247-V251 PolarHBondContact O-N 3.4Å
248	P	90.8	Very high	90.9	Very high	107 Å²	107	72.4 Å²	72.4	70%	0.695	39%	0.386	S	S	*	.	H	α-helix	trans	-60	-37.8	-175.2	-25.4	34.6	0	0	0	113.8	T246 K252	T246-P248 VanDerWaalsContact O-CD 3.29Å; T246-P248 WeakPolarHBondContact O-CD 3.36Å; P248-K252 VanDerWaalsContact O-CB 3.29Å; P248-K252 WeakPolarHBondContact O-CB 3.39Å; P248-K252 PolarHBondContact O-N 2.88Å
249	E	88.9	Confident	91.4	Very high	160 Å²	160	74 Å²	74	75%	0.748	39%	0.387	S	S	*	.	H	α-helix	trans	-66	-46.3	179.5	-64.4	-173.5	173.1	0	0	111.4	S247 K252 V253	S247-E249 VanDerWaalsContact C-N 3.31Å; S247-E249 PolarHBondContact O-N 3.2Å; E249-K252 PolarHBondContact O-N 3.42Å; E249-V253 WeakPolarHBondContact O-CG2 3.42Å; E249-V253 PolarHBondContact O-N 3.24Å; E249-V253 VanDerWaalsContact O-N 3.09Å
250	T	89.3	Confident	91.9	Very high	28 Å²	28	70.7 Å²	70.7	17%	0.172	37%	0.366	C	S	.	.	H	α-helix	trans	-66.1	-44.8	179.4	-54.2	0	0	0	0	111.1	F244 S247 K252 V253 V254	F244-T250 HydrophobicContact CD1-CG2 4.09Å; F244-T250 HydrophobicContact CD2-CG2 3.53Å; F244-T250 HydrophobicContact CE1-CG2 3.87Å; F244-T250 HydrophobicContact CE2-CG2 3.28Å; F244-T250 HydrophobicContact CG-CG2 3.92Å; F244-T250 HydrophobicContact CZ-CG2 3.45Å; F244-T250 VanDerWaalsContact CZ-CG2 3.45Å; S247-T250 PolarHBondContact O-N 3.4Å; S247-T250 PolarHBondContact OG-OG1 3.41Å; T250-K252 VanDerWaalsContact C-N 3.33Å; T250-K252 PolarHBondContact O-N 3.44Å; T250-V253 PolarHBondContact O-N 2.94Å; T250-V254 HydrophobicContact CG2-CG2 4.45Å; T250-V254 WeakPolarHBondContact O-CG2 3.42Å; T250-V254 PolarHBondContact O-N 3.5Å
251	V	90	Very high	92.2	Very high	38 Å²	38	70.5 Å²	70.5	23%	0.23	37%	0.365	C	S	.	.	H	α-helix	trans	-58.9	-45.8	176.4	171.6	0	0	0	0	110.7	F245 S247 V253 V254 M255	F245-V251 WeakPolarHBondContact O-CG2 3.41Å; S247-V251 WeakPolarHBondContact O-CB 3.26Å; S247-V251 VanDerWaalsContact O-CG2 3.26Å; S247-V251 WeakPolarHBondContact O-CG2 3.37Å; S247-V251 PolarHBondContact O-N 3.4Å; V251-V253 PolarHBondContact O-N 2.88Å; V251-V254 PolarHBondContact O-N 3.34Å; V251-M255 HydrophobicContact CG1-CE 3.7Å; V251-M255 HydrophobicContact CG1-CG 4.2Å; V251-M255 HydrophobicContact CG1-SD 3.88Å; V251-M255 WeakPolarHBondContact O-CB 3.25Å; V251-M255 VanDerWaalsContact O-CG 3.29Å; V251-M255 WeakPolarHBondContact O-CG 3.37Å; V251-M255 PolarHBondContact O-N 3.43Å
252	K	92.3	Very high	92.6	Very high	136 Å²	136	72 Å²	72	59%	0.591	38%	0.379	S	S	*	.	H	α-helix	trans	-58.2	-47.5	177.4	-176.4	179.3	179.7	-179.4	0	111.7	P248 E249 T250 M255 Q256	P248-K252 VanDerWaalsContact O-CB 3.29Å; P248-K252 WeakPolarHBondContact O-CB 3.39Å; P248-K252 PolarHBondContact O-N 2.88Å; E249-K252 PolarHBondContact O-N 3.42Å; T250-K252 VanDerWaalsContact C-N 3.33Å; T250-K252 PolarHBondContact O-N 3.44Å; K252-M255 PolarHBondContact O-N 3.18Å; K252-Q256 WeakPolarHBondContact O-CB 3.28Å; K252-Q256 VanDerWaalsContact O-CG 3.29Å; K252-Q256 WeakPolarHBondContact O-CG 3.44Å; K252-Q256 PolarHBondContact O-N 2.93Å
253	V	90.9	Very high	93	Very high	64 Å²	64	71.1 Å²	71.1	39%	0.388	38%	0.378	S	S	.	.	H	α-helix	trans	-64	-44.5	178.8	172.2	0	0	0	0	111.3	E249 T250 V251 Q256 V257	E249-V253 WeakPolarHBondContact O-CG2 3.42Å; E249-V253 PolarHBondContact O-N 3.24Å; E249-V253 VanDerWaalsContact O-N 3.09Å; T250-V253 PolarHBondContact O-N 2.94Å; V251-V253 PolarHBondContact O-N 2.88Å; V253-Q256 PolarHBondContact O-N 3.1Å; V253-V257 WeakPolarHBondContact O-CG2 3.28Å; V253-V257 PolarHBondContact O-N 3.39Å
254	V	92.4	Very high	93.3	Very high	17 Å²	17	67.5 Å²	67.5	10%	0.103	36%	0.359	C	S	.	.	H	α-helix	trans	-61.7	-49	178.2	169.3	0	0	0	0	110.4	V202 F244 T250 V251 Q256 V257 T258	V202-V254 HydrophobicContact CG2-CG1 3.87Å; F244-V254 HydrophobicContact CE1-CG2 4Å; F244-V254 HydrophobicContact CZ-CG2 3.85Å; T250-V254 HydrophobicContact CG2-CG2 4.45Å; T250-V254 WeakPolarHBondContact O-CG2 3.42Å; T250-V254 PolarHBondContact O-N 3.5Å; V251-V254 PolarHBondContact O-N 3.34Å; V254-Q256 PolarHBondContact O-N 2.98Å; V254-V257 PolarHBondContact O-N 3.05Å; V254-V257 VanDerWaalsContact O-N 3.14Å; V254-T258 HydrophobicContact CG1-CG2 4.13Å; V254-T258 WeakPolarHBondContact O-CG2 3.48Å; V254-T258 PolarHBondContact O-N 3.47Å; V254-T258 PolarHBondContact O-OG1 2.99Å
255	M	92.3	Very high	93.7	Very high	119 Å²	119	69 Å²	69	59%	0.586	37%	0.373	S	S	*	.	H	α-helix	trans	-60	-42	179.6	-74.8	-174.5	171.5	0	0	112.4	V251 K252 V257 T258 W259	V251-M255 HydrophobicContact CG1-CE 3.7Å; V251-M255 HydrophobicContact CG1-CG 4.2Å; V251-M255 HydrophobicContact CG1-SD 3.88Å; V251-M255 WeakPolarHBondContact O-CB 3.25Å; V251-M255 VanDerWaalsContact O-CG 3.29Å; V251-M255 WeakPolarHBondContact O-CG 3.37Å; V251-M255 PolarHBondContact O-N 3.43Å; K252-M255 PolarHBondContact O-N 3.18Å; M255-V257 PolarHBondContact O-N 3.05Å; M255-V257 VanDerWaalsContact O-N 3.16Å; M255-T258 PolarHBondContact O-N 2.96Å; M255-W259 WeakPolarHBondContact O-CB 3.44Å; M255-W259 PolarHBondContact O-N 3.21Å
256	Q	92.8	Very high	94	Very high	124 Å²	124	66.3 Å²	66.3	58%	0.579	37%	0.372	S	S	*	.	H	α-helix	trans	-59.5	-27.8	178.2	-79.6	179.2	-12.7	0	0	113.4	K252 V253 V254	K252-Q256 WeakPolarHBondContact O-CB 3.28Å; K252-Q256 VanDerWaalsContact O-CG 3.29Å; K252-Q256 WeakPolarHBondContact O-CG 3.44Å; K252-Q256 PolarHBondContact O-N 2.93Å; V253-Q256 PolarHBondContact O-N 3.1Å; V254-Q256 PolarHBondContact O-N 2.98Å
257	V	93.3	Very high	94.3	Very high	37 Å²	37	63.4 Å²	63.4	22%	0.224	36%	0.362	C	S	.	.	H	α-helix	trans	-95.9	-34.8	-179.3	-173.4	0	0	0	0	111.5	H173 V201 V253 V254 M255 P260	H173-V257 WeakPolarHBondContact CD2-CG1 3.21Å; H173-V257 WeakPolarHBondContact NE2-CG1 3.38Å; V201-V257 HydrophobicContact CG1-CB 4.24Å; V201-V257 HydrophobicContact CG1-CG1 3.54Å; V253-V257 WeakPolarHBondContact O-CG2 3.28Å; V253-V257 PolarHBondContact O-N 3.39Å; V254-V257 PolarHBondContact O-N 3.05Å; V254-V257 VanDerWaalsContact O-N 3.14Å; M255-V257 PolarHBondContact O-N 3.05Å; M255-V257 VanDerWaalsContact O-N 3.16Å; V257-P260 WeakPolarHBondContact O-CD 3.32Å
258	T	95.8	Very high	94.5	Very high	21 Å²	21	62.6 Å²	62.6	13%	0.129	35%	0.353	C	S	.	.	H	α-helix	trans	-94.8	-10.4	-172.7	62.4	0	0	0	0	114.8	V201 V202 V254 M255 P260 Y261 A262	V201-T258 HydrophobicContact CG1-CG2 4.26Å; V202-T258 HydrophobicContact CG2-CG2 3.97Å; V254-T258 HydrophobicContact CG1-CG2 4.13Å; V254-T258 WeakPolarHBondContact O-CG2 3.48Å; V254-T258 PolarHBondContact O-N 3.47Å; V254-T258 PolarHBondContact O-OG1 2.99Å; M255-T258 PolarHBondContact O-N 2.96Å; T258-P260 VanDerWaalsContact C-N 3.29Å; T258-P260 VanDerWaalsContact O-N 3.15Å; T258-Y261 WeakPolarHBondContact O-CB 2.98Å; T258-Y261 PolarHBondContact O-N 2.81Å; T258-A262 PolarHBondContact O-N 2.91Å; T258-A262 VanDerWaalsContact O-N 3.16Å
259	W	97.1	Very high	94.8	Very high	128 Å²	128	62.4 Å²	62.4	49%	0.485	35%	0.346	S	S	.	.	H	α-helix	trans	-51.9	-36.1	-179.9	79.2	-94.8	0	0	0	114.9	K174 M255 Y261 A262 V263	K174-W259 HydrophobicContact CD-CZ2 4.43Å; K174-W259 HydrophobicContact CG-CZ2 4.4Å; M255-W259 WeakPolarHBondContact O-CB 3.44Å; M255-W259 PolarHBondContact O-N 3.21Å; W259-Y261 VanDerWaalsContact C-N 3.26Å; W259-Y261 PolarHBondContact O-N 2.9Å; W259-A262 WeakPolarHBondContact O-CB 3.28Å; W259-A262 PolarHBondContact O-N 3.5Å; W259-A262 VanDerWaalsContact O-N 3.12Å; W259-V263 HydrophobicContact CE3-CG2 3.77Å; W259-V263 HydrophobicContact CZ3-CG2 4.03Å; W259-V263 WeakPolarHBondContact O-CG2 3.13Å; W259-V263 PolarHBondContact O-N 3.28Å
260	P	98.2	Very high	95.1	Very high	8 Å²	8	59.7 Å²	59.7	5%	0.052	34%	0.336	C	S	.	.	H	α-helix	trans	-62.3	-37.6	180	-22.5	35.9	0	0	0	111.5	H173 K174 A177 V257 T258 V263 V264	H173-P260 HydrophobicContact CB-CG 4.28Å; K174-P260 HydrophobicContact CG-CG 4.12Å; A177-P260 HydrophobicContact CB-CB 3.54Å; A177-P260 WeakPolarHBondContact CB-O 3.31Å; V257-P260 WeakPolarHBondContact O-CD 3.32Å; T258-P260 VanDerWaalsContact C-N 3.29Å; T258-P260 VanDerWaalsContact O-N 3.15Å; P260-V263 PolarHBondContact O-N 2.95Å; P260-V264 WeakPolarHBondContact O-CG2 3.35Å; P260-V264 PolarHBondContact O-N 3.31Å
261	Y	98.2	Very high	95.4	Very high	8 Å²	8	60.8 Å²	60.8	3%	0.031	34%	0.339	C	S	.	.	H	α-helix	trans	-71.9	-36.1	176.3	-52.1	-81.2	0	0	0	111.8	T168 H173 S176 A177 V194 C197 A198 T258 W259 V263 V264 A265	T168-Y261 PolarHBondContact OG1-OH 2.9Å; H173-Y261 HydrophobicContact CB-CE2 3.84Å; H173-Y261 AromaticContact ND1-CE2 3.68Å; H173-Y261 AromaticContact ND1-CZ 3.79Å; H173-Y261 PolarHBondContact ND1-OH 3.16Å; S176-Y261 VanDerWaalsContact CB-OH 3.3Å; S176-Y261 WeakPolarHBondContact CB-OH 3.16Å; S176-Y261 VanDerWaalsContact OG-CE1 3.3Å; S176-Y261 WeakPolarHBondContact OG-CE1 3.5Å; S176-Y261 PolarHBondContact OG-OH 3.26Å; S176-Y261 VanDerWaalsContact OG-OH 3.09Å; A177-Y261 HydrophobicContact CB-CD1 4.34Å; V194-Y261 HydrophobicContact CG1-CD1 3.88Å; C197-Y261 HydrophobicContact CB-CD1 4.28Å; C197-Y261 HydrophobicContact CB-CE1 3.67Å; A198-Y261 HydrophobicContact CB-CD1 4.45Å; A198-Y261 HydrophobicContact CB-CD2 3.92Å; A198-Y261 HydrophobicContact CB-CG 3.82Å; T258-Y261 WeakPolarHBondContact O-CB 2.98Å; T258-Y261 PolarHBondContact O-N 2.81Å; W259-Y261 VanDerWaalsContact C-N 3.26Å; W259-Y261 PolarHBondContact O-N 2.9Å; Y261-V263 VanDerWaalsContact C-N 3.3Å; Y261-V263 PolarHBondContact O-N 3.47Å; Y261-V264 PolarHBondContact O-N 3.45Å; Y261-A265 PolarHBondContact O-N 3.46Å
262	A	97.3	Very high	95.5	Very high	56 Å²	56	61.7 Å²	61.7	46%	0.463	34%	0.341	S	S	.	.	H	α-helix	trans	-62.5	-37.9	175.6	0	0	0	0	0	111.7	T258 W259 A265 A266	T258-A262 PolarHBondContact O-N 2.91Å; T258-A262 VanDerWaalsContact O-N 3.16Å; W259-A262 WeakPolarHBondContact O-CB 3.28Å; W259-A262 PolarHBondContact O-N 3.5Å; W259-A262 VanDerWaalsContact O-N 3.12Å; A262-A265 PolarHBondContact O-N 2.96Å; A262-A266 WeakPolarHBondContact O-CB 3.22Å; A262-A266 PolarHBondContact O-N 3.33Å
263	V	98.1	Very high	95.5	Very high	88 Å²	88	61.9 Å²	61.9	53%	0.533	35%	0.348	S	S	.	.	H	α-helix	trans	-62.3	-42.5	173.6	171.5	0	0	0	0	111.4	W259 P260 Y261 A266 G267	W259-V263 HydrophobicContact CE3-CG2 3.77Å; W259-V263 HydrophobicContact CZ3-CG2 4.03Å; W259-V263 WeakPolarHBondContact O-CG2 3.13Å; W259-V263 PolarHBondContact O-N 3.28Å; P260-V263 PolarHBondContact O-N 2.95Å; Y261-V263 VanDerWaalsContact C-N 3.3Å; Y261-V263 PolarHBondContact O-N 3.47Å; V263-A266 PolarHBondContact O-N 3.43Å; V263-G267 PolarHBondContact O-N 3.42Å
264	V	98.3	Very high	95.6	Very high	17 Å²	17	65.5 Å²	65.5	10%	0.103	36%	0.364	C	S	.	.	H	α-helix	trans	-63.4	-43.1	175.5	-179.3	0	0	0	0	111.1	A177 V181 I191 V194 P260 Y261 G267 F268	A177-V264 HydrophobicContact CB-CG2 3.96Å; V181-V264 HydrophobicContact CG2-CB 4.48Å; V181-V264 HydrophobicContact CG2-CG1 4.08Å; V181-V264 HydrophobicContact CG2-CG2 3.66Å; I191-V264 HydrophobicContact CD1-CG1 3.99Å; V194-V264 HydrophobicContact CG1-CB 4.33Å; V194-V264 HydrophobicContact CG1-CG1 4.16Å; P260-V264 WeakPolarHBondContact O-CG2 3.35Å; P260-V264 PolarHBondContact O-N 3.31Å; Y261-V264 PolarHBondContact O-N 3.45Å; V264-G267 PolarHBondContact O-N 2.61Å; V264-F268 WeakPolarHBondContact O-CB 3.28Å; V264-F268 PolarHBondContact O-N 3.34Å
265	A	97.6	Very high	95.6	Very high	39 Å²	39	65.7 Å²	65.7	32%	0.322	37%	0.365	S	S	.	.	H	α-helix	trans	-62.7	-45.4	176.3	0	0	0	0	0	112.2	Y261 A262 G267 F268 L269	Y261-A265 PolarHBondContact O-N 3.46Å; A262-A265 PolarHBondContact O-N 2.96Å; A265-G267 PolarHBondContact O-N 3.42Å; A265-F268 PolarHBondContact O-N 3.4Å; A265-L269 WeakPolarHBondContact O-CG 3.41Å; A265-L269 PolarHBondContact O-N 2.87Å
266	A	97.8	Very high	95.5	Very high	58 Å²	58	68.1 Å²	68.1	48%	0.479	37%	0.374	S	S	.	.	H	α-helix	trans	-61.8	-43.8	176.6	0	0	0	0	0	111.8	A262 V263 F268 L269 L270	A262-A266 WeakPolarHBondContact O-CB 3.22Å; A262-A266 PolarHBondContact O-N 3.33Å; V263-A266 PolarHBondContact O-N 3.43Å; A266-F268 VanDerWaalsContact C-N 3.33Å; A266-F268 PolarHBondContact O-N 3.49Å; A266-L269 PolarHBondContact O-N 2.75Å; A266-L270 WeakPolarHBondContact O-CB 3.48Å; A266-L270 PolarHBondContact O-N 3.09Å
267	G	97.6	Very high	95.1	Very high	40 Å²	40	63.3 Å²	63.3	41%	0.412	36%	0.358	S	S	.	.	H	α-helix	trans	-62.4	-39.2	175	0	0	0	0	0	112.8	V263 V264 A265 L270 F271	V263-G267 PolarHBondContact O-N 3.42Å; V264-G267 PolarHBondContact O-N 2.61Å; A265-G267 PolarHBondContact O-N 3.42Å; G267-L270 PolarHBondContact O-N 3.45Å; G267-F271 WeakPolarHBondContact O-CB 3.43Å; G267-F271 PolarHBondContact O-N 3.15Å
268	F	96.5	Very high	94.8	Very high	22 Å²	22	65 Å²	65	10%	0.096	37%	0.365	C	S	.	.	H	α-helix	trans	-68	-40.6	175.7	-175.7	-101.8	0	0	0	112.5	V184 Q188 I191 V264 A265 A266 F271 M272	V184-F268 HydrophobicContact CG1-CD2 3.74Å; V184-F268 HydrophobicContact CG1-CE2 4.05Å; Q188-F268 HydrophobicContact CB-CE2 3.84Å; Q188-F268 HydrophobicContact CB-CZ 3.96Å; Q188-F268 HydrophobicContact CG-CE2 4.25Å; I191-F268 HydrophobicContact CB-CD1 4.07Å; I191-F268 HydrophobicContact CB-CD2 4.49Å; I191-F268 HydrophobicContact CB-CE1 4.16Å; I191-F268 HydrophobicContact CB-CG 4.22Å; I191-F268 HydrophobicContact CB-CZ 4.43Å; I191-F268 HydrophobicContact CD1-CB 3.89Å; I191-F268 HydrophobicContact CD1-CD1 4.42Å; I191-F268 HydrophobicContact CD1-CG 4.12Å; I191-F268 HydrophobicContact CG1-CB 4.15Å; I191-F268 HydrophobicContact CG1-CD1 3.73Å; I191-F268 HydrophobicContact CG1-CE1 4.28Å; I191-F268 HydrophobicContact CG1-CG 3.9Å; I191-F268 HydrophobicContact CG2-CD1 4.02Å; I191-F268 HydrophobicContact CG2-CE1 3.68Å; I191-F268 HydrophobicContact CG2-CZ 4.03Å; V264-F268 WeakPolarHBondContact O-CB 3.28Å; V264-F268 PolarHBondContact O-N 3.34Å; A265-F268 PolarHBondContact O-N 3.4Å; A266-F268 VanDerWaalsContact C-N 3.33Å; A266-F268 PolarHBondContact O-N 3.49Å; F268-F271 HydrophobicContact CD2-CD1 4.16Å; F268-F271 HydrophobicContact CE2-CD1 4.1Å; F268-F271 HydrophobicContact CE2-CE1 4.34Å; F268-F271 WeakPolarHBondContact O-CB 3.18Å; F268-F271 PolarHBondContact O-N 2.88Å; F268-M272 HydrophobicContact CD1-CG 4.24Å; F268-M272 HydrophobicContact CD1-SD 3.81Å; F268-M272 HydrophobicContact CE1-CG 3.86Å; F268-M272 HydrophobicContact CE1-SD 3.28Å; F268-M272 WeakPolarHBondContact CE1-SD 3.45Å; F268-M272 HydrophobicContact CZ-CG 4.12Å; F268-M272 HydrophobicContact CZ-SD 4Å; F268-M272 WeakPolarHBondContact O-CG 3.48Å; F268-M272 PolarHBondContact O-N 3.5Å
269	L	95.8	Very high	94.3	Very high	103 Å²	103	64.9 Å²	64.9	54%	0.539	37%	0.365	S	S	.	.	H	α-helix	trans	-63.6	-43.5	174.4	-71.1	173.4	0	0	0	111.3	A265 A266 F271 M272 L273	A265-L269 WeakPolarHBondContact O-CG 3.41Å; A265-L269 PolarHBondContact O-N 2.87Å; A266-L269 PolarHBondContact O-N 2.75Å; L269-F271 VanDerWaalsContact C-N 3.33Å; L269-F271 PolarHBondContact O-N 2.85Å; L269-M272 PolarHBondContact O-N 3.26Å; L269-L273 WeakPolarHBondContact O-CG 3.32Å; L269-L273 PolarHBondContact O-N 3.3Å
270	L	96.4	Very high	93.8	Very high	102 Å²	102	60.6 Å²	60.6	53%	0.534	35%	0.352	S	S	.	.	H	α-helix	trans	-59.2	-45.2	173.7	179.5	62.1	0	0	0	111.1	A266 G267 M272 L273 L274	A266-L270 WeakPolarHBondContact O-CB 3.48Å; A266-L270 PolarHBondContact O-N 3.09Å; G267-L270 PolarHBondContact O-N 3.45Å; L270-M272 PolarHBondContact O-N 3.29Å; L270-L273 PolarHBondContact O-N 3.45Å; L270-L274 HydrophobicContact CD1-CD1 4.05Å; L270-L274 HydrophobicContact CD1-CG 4.21Å; L270-L274 HydrophobicContact CG-CD1 3.98Å; L270-L274 VanDerWaalsContact O-CG 3.3Å; L270-L274 WeakPolarHBondContact O-CG 3.33Å; L270-L274 PolarHBondContact O-N 3Å
271	F	94.8	Very high	93	Very high	52 Å²	52	60.4 Å²	60.4	23%	0.228	35%	0.352	C	S	.	.	H	α-helix	trans	-56.5	-46.9	173.2	160.5	-99	0	0	0	111.9	L66 G267 F268 L269 L273 L274 N275 V280	L66-F271 HydrophobicContact CD2-CE2 4.06Å; L66-F271 HydrophobicContact CD2-CZ 4.03Å; G267-F271 WeakPolarHBondContact O-CB 3.43Å; G267-F271 PolarHBondContact O-N 3.15Å; F268-F271 HydrophobicContact CD2-CD1 4.16Å; F268-F271 HydrophobicContact CE2-CD1 4.1Å; F268-F271 HydrophobicContact CE2-CE1 4.34Å; F268-F271 WeakPolarHBondContact O-CB 3.18Å; F268-F271 PolarHBondContact O-N 2.88Å; L269-F271 VanDerWaalsContact C-N 3.33Å; L269-F271 PolarHBondContact O-N 2.85Å; F271-L273 VanDerWaalsContact C-N 3.32Å; F271-L273 PolarHBondContact O-N 2.8Å; F271-L274 PolarHBondContact O-N 2.7Å; F271-N275 HydrophobicContact CD2-CB 4.2Å; F271-N275 HydrophobicContact CE1-CB 4.46Å; F271-N275 HydrophobicContact CE2-CB 3.76Å; F271-N275 HydrophobicContact CZ-CB 3.9Å; F271-N275 WeakPolarHBondContact O-CB 3.33Å; F271-N275 PolarHBondContact O-N 3.3Å; F271-V280 HydrophobicContact CE2-CG2 4.39Å; F271-V280 HydrophobicContact CZ-CG2 3.93Å
272	M	92.3	Very high	92.3	Very high	56 Å²	56	61.8 Å²	61.8	28%	0.276	36%	0.36	S	S	.	.	H	α-helix	trans	-61.5	-39.7	179.3	-74.9	-179.9	58.7	0	0	112.7	F268 L269 L270 E276 G277 I278	F268-M272 HydrophobicContact CD1-CG 4.24Å; F268-M272 HydrophobicContact CD1-SD 3.81Å; F268-M272 HydrophobicContact CE1-CG 3.86Å; F268-M272 HydrophobicContact CE1-SD 3.28Å; F268-M272 WeakPolarHBondContact CE1-SD 3.45Å; F268-M272 HydrophobicContact CZ-CG 4.12Å; F268-M272 HydrophobicContact CZ-SD 4Å; F268-M272 WeakPolarHBondContact O-CG 3.48Å; F268-M272 PolarHBondContact O-N 3.5Å; L269-M272 PolarHBondContact O-N 3.26Å; L270-M272 PolarHBondContact O-N 3.29Å; M272-E276 PolarHBondContact O-N 3.14Å; M272-G277 PolarHBondContact O-N 3.44Å; M272-I278 HydrophobicContact CE-CD1 4.29Å; M272-I278 HydrophobicContact CE-CG1 3.62Å; M272-I278 HydrophobicContact SD-CG1 4.25Å
273	L	92.9	Very high	91.7	Very high	141 Å²	141	64.5 Å²	64.5	74%	0.738	36%	0.358	S	S	*	.	H	α-helix	trans	-65.5	-43	177.1	-69.2	172.5	0	0	0	111.3	L269 L270 F271	L269-L273 WeakPolarHBondContact O-CG 3.32Å; L269-L273 PolarHBondContact O-N 3.3Å; L270-L273 PolarHBondContact O-N 3.45Å; F271-L273 VanDerWaalsContact C-N 3.32Å; F271-L273 PolarHBondContact O-N 2.8Å
274	L	93.4	Very high	90.8	Very high	139 Å²	139	65.7 Å²	65.7	73%	0.728	37%	0.366	S	S	*	.	H	α-helix	trans	-74.3	-31.5	179.1	-64.8	174.1	0	0	0	113	L270 F271	L270-L274 HydrophobicContact CD1-CD1 4.05Å; L270-L274 HydrophobicContact CD1-CG 4.21Å; L270-L274 HydrophobicContact CG-CD1 3.98Å; L270-L274 VanDerWaalsContact O-CG 3.3Å; L270-L274 WeakPolarHBondContact O-CG 3.33Å; L270-L274 PolarHBondContact O-N 3Å; F271-L274 PolarHBondContact O-N 2.7Å
275	N	92.1	Very high	90	Very high	22 Å²	22	65.3 Å²	65.3	12%	0.118	36%	0.364	C	S	.	.	H	α-helix	trans	-88.7	-6.9	-179.1	-178.6	60.4	0	0	0	113.2	F271 G277 V279 R283	F271-N275 HydrophobicContact CD2-CB 4.2Å; F271-N275 HydrophobicContact CE1-CB 4.46Å; F271-N275 HydrophobicContact CE2-CB 3.76Å; F271-N275 HydrophobicContact CZ-CB 3.9Å; F271-N275 WeakPolarHBondContact O-CB 3.33Å; F271-N275 PolarHBondContact O-N 3.3Å; N275-G277 PolarHBondContact ND2-O 3Å; N275-G277 PolarHBondContact O-N 3.19Å; N275-V279 PolarHBondContact ND2-O 3.47Å; N275-R283 VanDerWaalsContact O-CZ 3.26Å; N275-R283 PolarHBondContact O-NE 3.04Å; N275-R283 PolarHBondContact O-NH2 3.11Å; N275-R283 PolarHBondContact OD1-NH2 2.76Å
276	E	88.5	Confident	89.2	Confident	169 Å²	169	66.8 Å²	66.8	79%	0.79	36%	0.364	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.2	33.8	-176.7	-57.4	-178.6	171.8	0	0	113.3	M272	M272-E276 PolarHBondContact O-N 3.14Å
277	G	85.2	Confident	88.6	Confident	23 Å²	23	70.2 Å²	70.2	24%	0.237	37%	0.37	C	S	.	.	S	Bend	trans	165.2	169.8	-177.5	0	0	0	0	0	114.2	M272 N275	M272-G277 PolarHBondContact O-N 3.44Å; N275-G277 PolarHBondContact ND2-O 3Å; N275-G277 PolarHBondContact O-N 3.19Å
278	I	86.1	Confident	88.2	Confident	73 Å²	73	71.8 Å²	71.8	37%	0.374	38%	0.379	S	S	.	.	S	Bend	trans	-79.8	-41.4	179.2	-60.9	172.2	0	0	0	111	Q188 M272	Q188-I278 HydrophobicContact CB-CG2 3.95Å; Q188-I278 VanDerWaalsContact CG-O 3.28Å; Q188-I278 WeakPolarHBondContact CG-O 3.28Å; Q188-I278 PolarHBondContact NE2-O 3.17Å; M272-I278 HydrophobicContact CE-CD1 4.29Å; M272-I278 HydrophobicContact CE-CG1 3.62Å; M272-I278 HydrophobicContact SD-CG1 4.25Å
279	V	86.5	Confident	88	Confident	19 Å²	19	71.6 Å²	71.6	12%	0.115	38%	0.381	C	S	.	.			trans	-91.7	149.6	179	-61.6	0	0	0	0	111.7	N275 G281 R283 H286	N275-V279 PolarHBondContact ND2-O 3.47Å; V279-G281 VanDerWaalsContact CG2-O 3.24Å; V279-G281 WeakPolarHBondContact CG2-O 3.44Å; V279-R283 HydrophobicContact CG2-CB 4.41Å; V279-R283 HydrophobicContact CG2-CG 4.07Å; V279-H286 HydrophobicContact CB-CB 4.41Å; V279-H286 HydrophobicContact CG1-CB 3.89Å; V279-H286 HydrophobicContact CG2-CB 3.72Å
280	V	86.1	Confident	88	Confident	37 Å²	37	73.3 Å²	73.3	22%	0.224	38%	0.384	C	S	.	.	S	Bend	trans	-83	-35.4	-178	-176.3	0	0	0	0	111.6	T64 L66 F271	T64-V280 PolarHBondContact O-N 3.41Å; T64-V280 VanDerWaalsContact O-N 3.11Å; L66-V280 HydrophobicContact CD2-CG2 3.74Å; L66-V280 HydrophobicContact CG-CG2 4.29Å; F271-V280 HydrophobicContact CE2-CG2 4.39Å; F271-V280 HydrophobicContact CZ-CG2 3.93Å
281	G	82.5	Confident	88	Confident	5 Å²	5	68.5 Å²	68.5	5%	0.052	36%	0.358	C	S	.	.	S	Bend	trans	-126.6	169.1	178.9	0	0	0	0	0	112.5	P61 I63 T64 V279 R283	P61-G281 VanDerWaalsContact O-CA 3.25Å; P61-G281 WeakPolarHBondContact O-CA 3.29Å; I63-G281 VanDerWaalsContact O-CA 3.32Å; I63-G281 WeakPolarHBondContact O-CA 2.98Å; I63-G281 PolarHBondContact O-N 3.23Å; I63-G281 VanDerWaalsContact O-N 3.15Å; T64-G281 WeakPolarHBondContact CG2-O 3.47Å; V279-G281 VanDerWaalsContact CG2-O 3.24Å; V279-G281 WeakPolarHBondContact CG2-O 3.44Å; G281-R283 VanDerWaalsContact C-N 3.28Å; G281-R283 PolarHBondContact O-N 3.21Å; G281-R283 VanDerWaalsContact O-N 3.16Å
282	D	82.5	Confident	88.1	Confident	36 Å²	36	69.1 Å²	69.1	19%	0.193	36%	0.361	C	S	.	.			trans	41.3	47.6	-177.9	-170.3	19.8	0	0	0	114.5	P61 T64 T284 S285 H286 Y350	P61-D282 PolarHBondContact O-N 3.18Å; T64-D282 HydrophobicContact CG2-CB 3.89Å; D282-T284 VanDerWaalsContact C-N 3.27Å; D282-T284 PolarHBondContact O-N 2.97Å; D282-S285 PolarHBondContact O-N 3.15Å; D282-S285 WeakPolarHBondContact OD1-CB 3.48Å; D282-S285 PolarHBondContact OD1-OG 3.04Å; D282-S285 WeakPolarHBondContact OD2-CB 3.36Å; D282-S285 PolarHBondContact OD2-OG 3.14Å; D282-H286 PolarHBondContact O-ND1 3.06Å; D282-H286 IonicContact OD2-CE1 2.99Å; D282-H286 PolarHBondContact OD2-CE1 3.2Å; D282-H286 IonicContact OD2-ND1 3.33Å; D282-Y350 PolarHBondContact OD2-OH 3.06Å
283	R	84.1	Confident	88.3	Confident	113 Å²	113	66.5 Å²	66.5	43%	0.426	35%	0.348	S	S	.	.	G	3₁₀ helix	trans	-56.9	-37.6	-174	-65.3	-174.9	-175.4	120	2	113.4	N275 V279 G281 S285 H286	N275-R283 VanDerWaalsContact O-CZ 3.26Å; N275-R283 PolarHBondContact O-NE 3.04Å; N275-R283 PolarHBondContact O-NH2 3.11Å; N275-R283 PolarHBondContact OD1-NH2 2.76Å; V279-R283 HydrophobicContact CG2-CB 4.41Å; V279-R283 HydrophobicContact CG2-CG 4.07Å; G281-R283 VanDerWaalsContact C-N 3.28Å; G281-R283 PolarHBondContact O-N 3.21Å; G281-R283 VanDerWaalsContact O-N 3.16Å; R283-S285 PolarHBondContact O-N 2.99Å; R283-H286 CarbonylContact O-C 3.56Å; R283-H286 PolarHBondContact O-N 3.08Å; R283-H286 VanDerWaalsContact O-N 3.15Å
284	T	80.5	Confident	88.5	Confident	113 Å²	113	59.8 Å²	59.8	69%	0.693	31%	0.313	S	S	*	.	G	3₁₀ helix	trans	-64.6	-26.8	-177.1	48.2	0	0	0	0	113.4	D282	D282-T284 VanDerWaalsContact C-N 3.27Å; D282-T284 PolarHBondContact O-N 2.97Å
285	S	80.4	Confident	88.8	Confident	9 Å²	9	54 Å²	54	6%	0.063	28%	0.284	C	S	.	.	G	3₁₀ helix	trans	-95.6	2.2	179.2	-47.4	0	0	0	0	113	D282 R283 H348 K349 Y350	D282-S285 PolarHBondContact O-N 3.15Å; D282-S285 WeakPolarHBondContact OD1-CB 3.48Å; D282-S285 PolarHBondContact OD1-OG 3.04Å; D282-S285 WeakPolarHBondContact OD2-CB 3.36Å; D282-S285 PolarHBondContact OD2-OG 3.14Å; R283-S285 PolarHBondContact O-N 2.99Å; S285-H348 PolarHBondContact O-NE2 3.31Å; S285-K349 PolarHBondContact OG-NZ 3.16Å; S285-Y350 WeakPolarHBondContact CB-OH 3.36Å; S285-Y350 PolarHBondContact OG-OH 2.84Å
286	H	82.1	Confident	89	Confident	70 Å²	70	54 Å²	54	32%	0.324	28%	0.283	S	S	.	.			trans	-133.7	47.4	-174.3	-62.3	85.8	0	0	0	111.2	T64 V279 D282 R283	T64-H286 WeakPolarHBondContact CG2-CE1 3.22Å; V279-H286 HydrophobicContact CB-CB 4.41Å; V279-H286 HydrophobicContact CG1-CB 3.89Å; V279-H286 HydrophobicContact CG2-CB 3.72Å; D282-H286 PolarHBondContact O-ND1 3.06Å; D282-H286 IonicContact OD2-CE1 2.99Å; D282-H286 PolarHBondContact OD2-CE1 3.2Å; D282-H286 IonicContact OD2-ND1 3.33Å; R283-H286 CarbonylContact O-C 3.56Å; R283-H286 PolarHBondContact O-N 3.08Å; R283-H286 VanDerWaalsContact O-N 3.15Å
287	Q	84.8	Confident	89.5	Confident	130 Å²	130	46.4 Å²	46.4	61%	0.607	25%	0.247	S	C	*	.			trans	-79.3	141.8	174.6	-63	-172.6	2.4	0	0	110.5
288	A	87.8	Confident	90.1	Very high	73 Å²	73	45.3 Å²	45.3	60%	0.603	24%	0.236	S	C	*	.			trans	-70.2	135	173.7	0	0	0	0	0	109.8	P413	A288-P413 HydrophobicContact CB-CB 4.4Å
289	C	92.6	Very high	90.7	Very high	19 Å²	19	43 Å²	43	13%	0.128	22%	0.223	C	C	.	.			trans	-131.3	168.2	176.2	65	0	0	0	0	110.9	H291 Y346 P413 E415	C289-H291 PolarHBondContact O-N 3.34Å; C289-Y346 HydrophobicContact CB-CD1 4.49Å; C289-Y346 HydrophobicContact CB-CD2 4.44Å; C289-Y346 HydrophobicContact CB-CE1 4.27Å; C289-Y346 HydrophobicContact CB-CE2 4.23Å; C289-P413 PolarHBondContact N-O 3.29Å; C289-P413 VanDerWaalsContact O-CA 3.24Å; C289-P413 WeakPolarHBondContact O-CA 3.16Å; C289-E415 WeakPolarHBondContact SG-CA 3.48Å
290	F	95.5	Very high	91.2	Very high	139 Å²	139	44 Å²	44	61%	0.61	23%	0.231	S	C	*	.			trans	-93	66.2	174.8	-68.6	-67.9	0	0	0	110.7	F292 F344 I412	F290-F292 VanDerWaalsContact C-N 3.33Å; F290-F292 HydrophobicContact CB-CD2 4.26Å; F290-F292 HydrophobicContact CB-CE2 3.85Å; F290-F292 WeakPolarHBondContact O-CD2 3.2Å; F290-F292 PolarHBondContact O-N 3.11Å; F290-F344 HydrophobicContact CB-CD1 3.91Å; F290-F344 HydrophobicContact CB-CE1 3.95Å; F290-F344 VanDerWaalsContact O-CB 3.28Å; F290-F344 WeakPolarHBondContact O-CB 3.18Å; F290-F344 WeakPolarHBondContact O-CD1 3.26Å; F290-F344 WeakPolarHBondContact O-CG 3.44Å; F290-I412 HydrophobicContact CD1-CG2 4.48Å
291	H	96.5	Very high	91.8	Very high	0 Å²	0	42.8 Å²	42.8	0%	0	22%	0.222	C	C	.	.			trans	-84.8	67.3	-177.5	-164.6	176.7	0	0	0	112.2	C289 P293 Q294 Y297 F344 Y346 I412 Q414 E415	C289-H291 PolarHBondContact O-N 3.34Å; H291-P293 VanDerWaalsContact C-N 3.34Å; H291-Q294 HydrophobicContact CB-CG 3.86Å; H291-Q294 PolarHBondContact ND1-NE2 2.74Å; H291-Q294 VanDerWaalsContact O-CB 3.29Å; H291-Q294 WeakPolarHBondContact O-CB 3.46Å; H291-Q294 VanDerWaalsContact O-CG 3.3Å; H291-Q294 WeakPolarHBondContact O-CG 3.42Å; H291-Q294 PolarHBondContact O-N 2.89Å; H291-Y297 AromaticContact NE2-CE2 3.74Å; H291-F344 PolarHBondContact CD2-O 2.89Å; H291-Y346 HydrophobicContact CB-CD2 3.77Å; H291-Y346 HydrophobicContact CB-CE2 4.47Å; H291-Y346 PolarHBondContact CE1-O 2.88Å; H291-Y346 AromaticContact CG-CD2 3.87Å; H291-Y346 PolarHBondContact NE2-N 3.05Å; H291-I412 WeakPolarHBondContact CA-O 3.26Å; H291-I412 WeakPolarHBondContact CB-O 3.27Å; H291-I412 PolarHBondContact N-O 2.86Å; H291-Q414 WeakPolarHBondContact CB-O 3.29Å; H291-Q414 PolarHBondContact ND1-O 3.5Å; H291-Q414 VanDerWaalsContact ND1-O 3.16Å; H291-E415 PolarHBondContact ND1-O 3.39Å
292	F	97.2	Very high	92.5	Very high	66 Å²	66	42.6 Å²	42.6	29%	0.289	22%	0.22	S	C	.	.	T	Hydrogen-bonded Turn	trans	-50.8	-41	-178.7	-71.8	-86.7	0	0	0	115.1	F290 Q294 V295 L340 F344 I412	F290-F292 VanDerWaalsContact C-N 3.33Å; F290-F292 HydrophobicContact CB-CD2 4.26Å; F290-F292 HydrophobicContact CB-CE2 3.85Å; F290-F292 WeakPolarHBondContact O-CD2 3.2Å; F290-F292 PolarHBondContact O-N 3.11Å; F292-Q294 PolarHBondContact O-N 3.31Å; F292-V295 PolarHBondContact O-N 3.02Å; F292-L340 HydrophobicContact CB-CB 4.29Å; F292-L340 HydrophobicContact CB-CD1 4.31Å; F292-L340 HydrophobicContact CB-CD2 4.08Å; F292-L340 HydrophobicContact CB-CG 4.46Å; F292-L340 HydrophobicContact CD1-CD2 4.26Å; F292-L340 HydrophobicContact CD2-CD2 3.91Å; F292-L340 HydrophobicContact CE2-CD2 4.4Å; F292-L340 HydrophobicContact CG-CD2 3.83Å; F292-F344 HydrophobicContact CB-CB 4.35Å; F292-F344 HydrophobicContact CD2-CB 3.91Å; F292-F344 AromaticContact CD2-CD1 3.96Å; F292-F344 HydrophobicContact CD2-CD1 3.96Å; F292-F344 AromaticContact CD2-CD2 3.73Å; F292-F344 HydrophobicContact CD2-CD2 3.73Å; F292-F344 HydrophobicContact CD2-CE1 4.38Å; F292-F344 HydrophobicContact CD2-CE2 4.18Å; F292-F344 AromaticContact CD2-CG 3.6Å; F292-F344 HydrophobicContact CD2-CG 3.6Å; F292-F344 HydrophobicContact CD2-CZ 4.48Å; F292-F344 HydrophobicContact CE2-CD1 4.18Å; F292-F344 HydrophobicContact CE2-CD2 4.17Å; F292-F344 HydrophobicContact CE2-CE1 4.15Å; F292-F344 HydrophobicContact CE2-CE2 4.15Å; F292-F344 HydrophobicContact CE2-CG 4.18Å; F292-F344 HydrophobicContact CE2-CZ 4.14Å; F292-I412 HydrophobicContact CD1-CD1 3.53Å; F292-I412 HydrophobicContact CE1-CD1 3.78Å; F292-I412 HydrophobicContact CG-CD1 4.29Å
293	P	97.3	Very high	93.2	Very high	0 Å²	0	42.8 Å²	42.8	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-50	-22	172.2	-33.2	34.5	0	0	0	116.8	H291 V295 F296 Y297 F344	H291-P293 VanDerWaalsContact C-N 3.34Å; P293-V295 PolarHBondContact O-N 3.32Å; P293-F296 HydrophobicContact CB-CD2 4.34Å; P293-F296 WeakPolarHBondContact O-CA 3.34Å; P293-F296 VanDerWaalsContact O-CB 3.31Å; P293-F296 WeakPolarHBondContact O-CB 3.33Å; P293-F296 PolarHBondContact O-N 3.07Å; P293-Y297 HydrophobicContact CB-CE1 4.13Å; P293-Y297 HydrophobicContact CB-CE2 3.86Å; P293-Y297 WeakPolarHBondContact O-CD1 3.43Å; P293-Y297 WeakPolarHBondContact O-CD2 3.34Å; P293-Y297 VanDerWaalsContact O-CG 3.22Å; P293-Y297 PolarHBondContact O-N 3.13Å; P293-F344 WeakPolarHBondContact CD-O 3.32Å
294	Q	97.6	Very high	93.8	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-56.4	-34.7	174.1	-69.5	-78.8	26.6	0	0	112.8	H291 F292 F296 Y297 F298 T411 Q414 L416	H291-Q294 HydrophobicContact CB-CG 3.86Å; H291-Q294 PolarHBondContact ND1-NE2 2.74Å; H291-Q294 VanDerWaalsContact O-CB 3.29Å; H291-Q294 WeakPolarHBondContact O-CB 3.46Å; H291-Q294 VanDerWaalsContact O-CG 3.3Å; H291-Q294 WeakPolarHBondContact O-CG 3.42Å; H291-Q294 PolarHBondContact O-N 2.89Å; F292-Q294 PolarHBondContact O-N 3.31Å; Q294-F296 VanDerWaalsContact C-N 3.34Å; Q294-Y297 PolarHBondContact O-N 2.96Å; Q294-F298 WeakPolarHBondContact O-CB 3.46Å; Q294-F298 PolarHBondContact O-N 2.95Å; Q294-T411 WeakPolarHBondContact CB-O 3.23Å; Q294-T411 WeakPolarHBondContact CG-O 3.45Å; Q294-Q414 PolarHBondContact NE2-O 2.85Å; Q294-L416 PolarHBondContact NE2-O 2.95Å
295	V	98.1	Very high	94.7	Very high	18 Å²	18	37 Å²	37	11%	0.109	19%	0.186	C	C	.	.	H	α-helix	trans	-67.7	-37.8	175.1	179.4	0	0	0	0	110.8	F292 P293 F298 F299 V408 T411 I412	F292-V295 PolarHBondContact O-N 3.02Å; P293-V295 PolarHBondContact O-N 3.32Å; V295-F298 PolarHBondContact O-N 3.45Å; V295-F299 HydrophobicContact CG1-CD2 4.25Å; V295-F299 HydrophobicContact CG1-CE1 4.06Å; V295-F299 HydrophobicContact CG1-CE2 3.61Å; V295-F299 HydrophobicContact CG1-CZ 3.49Å; V295-F299 VanDerWaalsContact CG1-CZ 3.49Å; V295-F299 WeakPolarHBondContact O-CD2 3.42Å; V295-F299 VanDerWaalsContact O-CG 3.31Å; V295-F299 WeakPolarHBondContact O-CG 3.2Å; V295-F299 PolarHBondContact O-N 3.28Å; V295-V408 HydrophobicContact CG2-CG2 4.46Å; V295-T411 WeakPolarHBondContact CG2-OG1 3.44Å; V295-I412 HydrophobicContact CG2-CD1 4.1Å; V295-I412 HydrophobicContact CG2-CG1 3.74Å
296	F	98.1	Very high	95.4	Very high	23 Å²	23	36.6 Å²	36.6	10%	0.101	18%	0.184	C	C	.	.	H	α-helix	trans	-67.1	-42.8	175.9	-56.2	-27	0	0	0	111.5	P293 Q294 F298 F299 C300 L340 V341 Y381	P293-F296 HydrophobicContact CB-CD2 4.34Å; P293-F296 WeakPolarHBondContact O-CA 3.34Å; P293-F296 VanDerWaalsContact O-CB 3.31Å; P293-F296 WeakPolarHBondContact O-CB 3.33Å; P293-F296 PolarHBondContact O-N 3.07Å; Q294-F296 VanDerWaalsContact C-N 3.34Å; F296-F298 VanDerWaalsContact C-N 3.31Å; F296-F298 PolarHBondContact O-N 3.04Å; F296-F299 PolarHBondContact O-N 2.88Å; F296-C300 PolarHBondContact O-N 2.99Å; F296-L340 HydrophobicContact CE2-CB 4.24Å; F296-L340 HydrophobicContact CZ-CB 4.4Å; F296-L340 HydrophobicContact CZ-CD1 4.04Å; F296-V341 HydrophobicContact CD2-CG2 4.01Å; F296-V341 HydrophobicContact CE2-CG2 3.94Å; F296-Y381 HydrophobicContact CB-CD1 3.73Å; F296-Y381 HydrophobicContact CB-CD2 3.82Å; F296-Y381 HydrophobicContact CB-CE1 4.11Å; F296-Y381 HydrophobicContact CB-CE2 4.2Å; F296-Y381 HydrophobicContact CB-CG 3.61Å; F296-Y381 AromaticContact CD2-CD2 3.89Å; F296-Y381 HydrophobicContact CD2-CD2 3.89Å; F296-Y381 HydrophobicContact CD2-CE2 4.32Å; F296-Y381 HydrophobicContact CD2-CG 4.41Å; F296-Y381 HydrophobicContact CG-CD2 4.02Å; F296-Y381 HydrophobicContact CG-CG 4.06Å
297	Y	97.8	Very high	96	Very high	9 Å²	9	36 Å²	36	4%	0.035	18%	0.183	C	C	.	.	H	α-helix	trans	-60.6	-43.2	173.8	-54.2	-27.2	0	0	0	110.8	H291 P293 Q294 F299 C300 F301 W363 Y367 Y381 L417	H291-Y297 AromaticContact NE2-CE2 3.74Å; P293-Y297 HydrophobicContact CB-CE1 4.13Å; P293-Y297 HydrophobicContact CB-CE2 3.86Å; P293-Y297 WeakPolarHBondContact O-CD1 3.43Å; P293-Y297 WeakPolarHBondContact O-CD2 3.34Å; P293-Y297 VanDerWaalsContact O-CG 3.22Å; P293-Y297 PolarHBondContact O-N 3.13Å; Q294-Y297 PolarHBondContact O-N 2.96Å; Y297-F299 PolarHBondContact O-N 2.91Å; Y297-C300 PolarHBondContact O-N 3.33Å; Y297-F301 WeakPolarHBondContact O-CB 3.24Å; Y297-F301 PolarHBondContact O-N 3.48Å; Y297-W363 HydrophobicContact CE2-CZ3 4.47Å; Y297-Y367 WeakPolarHBondContact CD1-OH 3.2Å; Y297-Y367 AromaticContact CE1-CE1 3.84Å; Y297-Y367 HydrophobicContact CE1-CE1 3.84Å; Y297-Y367 AromaticContact CE1-CZ 3.74Å; Y297-Y367 WeakPolarHBondContact CE1-OH 3.24Å; Y297-Y381 HydrophobicContact CD1-CE1 4.36Å; Y297-Y381 WeakPolarHBondContact CE1-OH 3.05Å; Y297-L417 HydrophobicContact CD2-CD1 3.73Å; Y297-L417 HydrophobicContact CD2-CD2 4.03Å; Y297-L417 HydrophobicContact CD2-CG 4.36Å; Y297-L417 HydrophobicContact CE2-CD2 4.22Å; Y297-L417 HydrophobicContact CG-CD1 4.19Å; Y297-L417 HydrophobicContact CG-CD2 4.46Å
298	F	98.4	Very high	96.4	Very high	0 Å²	0	31.4 Å²	31.4	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-61.8	-39	174.8	177.4	-100.7	0	0	0	112.8	Q294 V295 F296 F301 T302 F388 L407 F422 P425	Q294-F298 WeakPolarHBondContact O-CB 3.46Å; Q294-F298 PolarHBondContact O-N 2.95Å; V295-F298 PolarHBondContact O-N 3.45Å; F296-F298 VanDerWaalsContact C-N 3.31Å; F296-F298 PolarHBondContact O-N 3.04Å; F298-F301 HydrophobicContact CD2-CD1 4.48Å; F298-F301 PolarHBondContact O-N 3.33Å; F298-T302 WeakPolarHBondContact CE1-OG1 3.49Å; F298-T302 WeakPolarHBondContact CE2-OG1 3.32Å; F298-T302 WeakPolarHBondContact CZ-OG1 3.43Å; F298-T302 VanDerWaalsContact O-CB 3.25Å; F298-T302 WeakPolarHBondContact O-CB 3.29Å; F298-T302 PolarHBondContact O-N 3.45Å; F298-T302 PolarHBondContact O-OG1 3.26Å; F298-F388 HydrophobicContact CE1-CD2 4.5Å; F298-F388 AromaticContact CE1-CE2 3.64Å; F298-F388 HydrophobicContact CE1-CE2 3.64Å; F298-F388 AromaticContact CE1-CZ 3.88Å; F298-F388 HydrophobicContact CE1-CZ 3.88Å; F298-F388 HydrophobicContact CZ-CE2 4.3Å; F298-L407 HydrophobicContact CD1-CD1 3.42Å; F298-L407 VanDerWaalsContact CD1-CD1 3.42Å; F298-L407 HydrophobicContact CD1-CD2 3.69Å; F298-L407 HydrophobicContact CD1-CG 4.15Å; F298-L407 HydrophobicContact CD2-CD1 4.23Å; F298-L407 HydrophobicContact CE1-CD1 3.44Å; F298-L407 VanDerWaalsContact CE1-CD1 3.44Å; F298-L407 HydrophobicContact CE1-CD2 3.67Å; F298-L407 HydrophobicContact CE1-CG 4.21Å; F298-L407 HydrophobicContact CE2-CD1 4.26Å; F298-L407 HydrophobicContact CG-CD1 3.83Å; F298-L407 HydrophobicContact CZ-CD1 3.88Å; F298-F422 HydrophobicContact CB-CD1 4.17Å; F298-F422 HydrophobicContact CB-CE1 3.99Å; F298-F422 HydrophobicContact CB-CE2 4.47Å; F298-F422 HydrophobicContact CB-CZ 4.15Å; F298-F422 HydrophobicContact CD2-CB 3.78Å; F298-F422 AromaticContact CD2-CD1 3.72Å; F298-F422 HydrophobicContact CD2-CD1 3.72Å; F298-F422 HydrophobicContact CD2-CD2 4.33Å; F298-F422 HydrophobicContact CD2-CE1 4.4Å; F298-F422 AromaticContact CD2-CG 3.69Å; F298-F422 HydrophobicContact CD2-CG 3.69Å; F298-F422 HydrophobicContact CE2-CB 4.12Å; F298-F422 HydrophobicContact CG-CD1 4.39Å; F298-P425 HydrophobicContact CE2-CB 3.69Å; F298-P425 HydrophobicContact CE2-CG 3.99Å; F298-P425 HydrophobicContact CZ-CB 3.7Å; F298-P425 HydrophobicContact CZ-CG 4.48Å
299	F	98.2	Very high	96.6	Very high	24 Å²	24	28 Å²	28	11%	0.105	14%	0.136	C	C	.	.	H	α-helix	trans	-65.4	-44.1	175.7	-66.7	-29	0	0	0	112.3	V295 F296 Y297 T302 Y303 T384 G385 F388 L407	V295-F299 HydrophobicContact CG1-CD2 4.25Å; V295-F299 HydrophobicContact CG1-CE1 4.06Å; V295-F299 HydrophobicContact CG1-CE2 3.61Å; V295-F299 HydrophobicContact CG1-CZ 3.49Å; V295-F299 VanDerWaalsContact CG1-CZ 3.49Å; V295-F299 WeakPolarHBondContact O-CD2 3.42Å; V295-F299 VanDerWaalsContact O-CG 3.31Å; V295-F299 WeakPolarHBondContact O-CG 3.2Å; V295-F299 PolarHBondContact O-N 3.28Å; F296-F299 PolarHBondContact O-N 2.88Å; Y297-F299 PolarHBondContact O-N 2.91Å; F299-T302 PolarHBondContact O-N 2.97Å; F299-Y303 VanDerWaalsContact O-CB 3.29Å; F299-Y303 WeakPolarHBondContact O-CB 3.34Å; F299-Y303 PolarHBondContact O-N 3.23Å; F299-T384 WeakPolarHBondContact CB-OG1 3.36Å; F299-G385 VanDerWaalsContact CD2-CA 3.44Å; F299-F388 HydrophobicContact CD1-CB 4.01Å; F299-F388 HydrophobicContact CD1-CD1 4.06Å; F299-F388 HydrophobicContact CD1-CD2 4.02Å; F299-F388 AromaticContact CD1-CG 3.76Å; F299-F388 HydrophobicContact CD1-CG 3.76Å; F299-F388 HydrophobicContact CE1-CB 4.25Å; F299-F388 AromaticContact CE1-CD1 3.58Å; F299-F388 HydrophobicContact CE1-CD1 3.58Å; F299-F388 HydrophobicContact CE1-CD2 4.33Å; F299-F388 AromaticContact CE1-CE1 3.99Å; F299-F388 HydrophobicContact CE1-CE1 3.99Å; F299-F388 AromaticContact CE1-CG 3.79Å; F299-F388 HydrophobicContact CE1-CG 3.79Å; F299-F388 HydrophobicContact CZ-CD1 4.47Å; F299-L407 HydrophobicContact CE1-CD2 4.12Å
300	C	97.7	Very high	96.3	Very high	41 Å²	41	27.1 Å²	27.1	28%	0.277	13%	0.13	S	C	.	.	H	α-helix	trans	-62.4	-46	173.8	-75.3	0	0	0	0	112	F296 Y297 T302 Y303 F304 Y381	F296-C300 PolarHBondContact O-N 2.99Å; Y297-C300 PolarHBondContact O-N 3.33Å; C300-T302 PolarHBondContact O-N 3.48Å; C300-Y303 PolarHBondContact O-N 3.01Å; C300-F304 WeakPolarHBondContact O-CB 3.1Å; C300-F304 PolarHBondContact O-N 3.47Å; C300-Y381 WeakPolarHBondContact SG-CD1 3.22Å
301	F	98	Very high	95.7	Very high	10 Å²	10	24.6 Å²	24.6	4%	0.044	12%	0.122	C	C	.	.	H	α-helix	trans	-56	-50.4	175.9	175.9	-92.8	0	0	0	111.3	F141 V143 Y297 F298 Y303 F304 F305 F419 F422 Y426	F141-F301 HydrophobicContact CE1-CZ 4.36Å; F141-F301 HydrophobicContact CE2-CZ 4.48Å; F141-F301 AromaticContact CZ-CE1 3.81Å; F141-F301 HydrophobicContact CZ-CE1 3.81Å; F141-F301 AromaticContact CZ-CZ 3.57Å; F141-F301 HydrophobicContact CZ-CZ 3.57Å; V143-F301 HydrophobicContact CG2-CE2 3.96Å; V143-F301 HydrophobicContact CG2-CZ 3.91Å; Y297-F301 WeakPolarHBondContact O-CB 3.24Å; Y297-F301 PolarHBondContact O-N 3.48Å; F298-F301 HydrophobicContact CD2-CD1 4.48Å; F298-F301 PolarHBondContact O-N 3.33Å; F301-Y303 VanDerWaalsContact C-N 3.35Å; F301-Y303 PolarHBondContact O-N 3.23Å; F301-F304 PolarHBondContact O-N 3.29Å; F301-F305 HydrophobicContact CD1-CD2 4.22Å; F301-F305 AromaticContact CD2-CD2 3.83Å; F301-F305 HydrophobicContact CD2-CD2 3.83Å; F301-F305 AromaticContact CD2-CE2 3.6Å; F301-F305 HydrophobicContact CD2-CE2 3.6Å; F301-F305 HydrophobicContact CE1-CD2 4.07Å; F301-F305 HydrophobicContact CE1-CE2 4.47Å; F301-F305 AromaticContact CE2-CD2 3.67Å; F301-F305 HydrophobicContact CE2-CD2 3.67Å; F301-F305 AromaticContact CE2-CE2 3.26Å; F301-F305 HydrophobicContact CE2-CE2 3.26Å; F301-F305 HydrophobicContact CE2-CZ 4.32Å; F301-F305 HydrophobicContact CG-CD2 4.12Å; F301-F305 HydrophobicContact CG-CE2 4.35Å; F301-F305 AromaticContact CZ-CD2 3.83Å; F301-F305 HydrophobicContact CZ-CD2 3.83Å; F301-F305 AromaticContact CZ-CE2 3.78Å; F301-F305 HydrophobicContact CZ-CE2 3.78Å; F301-F305 WeakPolarHBondContact O-CD2 3.37Å; F301-F305 PolarHBondContact O-N 2.98Å; F301-F419 HydrophobicContact CD2-CB 4.39Å; F301-F419 AromaticContact CD2-CD1 3.87Å; F301-F419 HydrophobicContact CD2-CD1 3.87Å; F301-F419 HydrophobicContact CD2-CD2 4.48Å; F301-F419 HydrophobicContact CD2-CE1 4.25Å; F301-F419 HydrophobicContact CD2-CG 4Å; F301-F419 HydrophobicContact CE2-CB 3.72Å; F301-F419 HydrophobicContact CE2-CD1 4.08Å; F301-F419 HydrophobicContact CE2-CD2 4.24Å; F301-F419 AromaticContact CE2-CG 3.76Å; F301-F419 HydrophobicContact CE2-CG 3.76Å; F301-F419 HydrophobicContact CZ-CB 4.4Å; F301-F422 HydrophobicContact CB-CD2 3.96Å; F301-F422 HydrophobicContact CB-CE2 4.34Å; F301-F422 HydrophobicContact CD1-CB 3.73Å; F301-F422 AromaticContact CD1-CD2 3.91Å; F301-F422 HydrophobicContact CD1-CD2 3.91Å; F301-F422 HydrophobicContact CD1-CG 4.23Å; F301-F422 AromaticContact CD2-CD2 3.9Å; F301-F422 HydrophobicContact CD2-CD2 3.9Å; F301-F422 HydrophobicContact CE1-CB 3.46Å; F301-F422 VanDerWaalsContact CE1-CB 3.46Å; F301-F422 HydrophobicContact CE1-CD2 4.31Å; F301-F422 HydrophobicContact CE1-CG 4.39Å; F301-F422 HydrophobicContact CE2-CB 4.49Å; F301-F422 HydrophobicContact CE2-CD2 4.29Å; F301-F422 HydrophobicContact CG-CB 4.33Å; F301-F422 AromaticContact CG-CD2 3.67Å; F301-F422 HydrophobicContact CG-CD2 3.67Å; F301-F422 HydrophobicContact CG-CE2 4.47Å; F301-F422 HydrophobicContact CG-CG 4.44Å; F301-F422 HydrophobicContact CZ-CB 3.86Å; F301-F422 HydrophobicContact CZ-CD2 4.45Å; F301-Y426 HydrophobicContact CD1-CD2 4.42Å; F301-Y426 HydrophobicContact CE1-CD2 4.25Å; F301-Y426 HydrophobicContact CE1-CG 4.19Å
302	T	97.9	Very high	95.1	Very high	1 Å²	1	26.2 Å²	26.2	1%	0.006	13%	0.133	C	C	.	.	H	α-helix	trans	-63.3	-42.7	179.1	-61.8	0	0	0	0	111.4	F298 F299 C300 S306 F388 Y426 Y429	F298-T302 WeakPolarHBondContact CE1-OG1 3.49Å; F298-T302 WeakPolarHBondContact CE2-OG1 3.32Å; F298-T302 WeakPolarHBondContact CZ-OG1 3.43Å; F298-T302 VanDerWaalsContact O-CB 3.25Å; F298-T302 WeakPolarHBondContact O-CB 3.29Å; F298-T302 PolarHBondContact O-N 3.45Å; F298-T302 PolarHBondContact O-OG1 3.26Å; F299-T302 PolarHBondContact O-N 2.97Å; C300-T302 PolarHBondContact O-N 3.48Å; T302-S306 VanDerWaalsContact O-CB 3.25Å; T302-S306 WeakPolarHBondContact O-CB 3.24Å; T302-S306 PolarHBondContact O-N 2.98Å; T302-S306 PolarHBondContact O-OG 3.41Å; T302-F388 HydrophobicContact CG2-CD2 3.79Å; T302-F388 HydrophobicContact CG2-CE2 3.85Å; T302-Y426 HydrophobicContact CG2-CD2 3.97Å; T302-Y426 HydrophobicContact CG2-CE2 3.99Å; T302-Y429 HydrophobicContact CG2-CD1 3.41Å; T302-Y429 VanDerWaalsContact CG2-CD1 3.41Å; T302-Y429 HydrophobicContact CG2-CE1 3.27Å; T302-Y429 HydrophobicContact CG2-CG 4.16Å
303	Y	97.1	Very high	94.6	Very high	40 Å²	40	29.1 Å²	29.1	16%	0.157	15%	0.151	C	C	.	.	H	α-helix	trans	-63	-42.7	178.5	-177.3	-104.1	0	0	0	111.8	F299 C300 F301 S306 L307 L311 F383 T384 N387	F299-Y303 VanDerWaalsContact O-CB 3.29Å; F299-Y303 WeakPolarHBondContact O-CB 3.34Å; F299-Y303 PolarHBondContact O-N 3.23Å; C300-Y303 PolarHBondContact O-N 3.01Å; F301-Y303 VanDerWaalsContact C-N 3.35Å; F301-Y303 PolarHBondContact O-N 3.23Å; Y303-S306 CarbonylContact O-C 3.6Å; Y303-L307 HydrophobicContact CD1-CD1 4.25Å; Y303-L307 HydrophobicContact CE1-CD1 3.57Å; Y303-L307 HydrophobicContact CE2-CD1 4.45Å; Y303-L307 VanDerWaalsContact O-CA 3.26Å; Y303-L307 WeakPolarHBondContact O-CA 3.38Å; Y303-L307 WeakPolarHBondContact O-CB 3.31Å; Y303-L307 PolarHBondContact O-N 2.63Å; Y303-L311 WeakPolarHBondContact OH-CD1 3.3Å; Y303-F383 HydrophobicContact CE1-CE1 4.19Å; Y303-F383 AromaticContact CE2-CE1 3.97Å; Y303-F383 HydrophobicContact CE2-CE1 3.97Å; Y303-F383 HydrophobicContact CE2-CZ 4.42Å; Y303-F383 AromaticContact CZ-CE1 3.65Å; Y303-T384 HydrophobicContact CD1-CG2 3.79Å; Y303-T384 HydrophobicContact CD2-CG2 4.35Å; Y303-T384 HydrophobicContact CG-CG2 3.65Å; Y303-N387 HydrophobicContact CD2-CB 4.34Å; Y303-N387 HydrophobicContact CE2-CB 4.48Å
304	F	97.2	Very high	94.2	Very high	99 Å²	99	34.6 Å²	34.6	43%	0.434	18%	0.177	S	C	.	.	H	α-helix	trans	-61.9	-54.6	176.7	175.8	-97.5	0	0	0	111.8	C300 F301 S306 L307 L447	C300-F304 WeakPolarHBondContact O-CB 3.1Å; C300-F304 PolarHBondContact O-N 3.47Å; F301-F304 PolarHBondContact O-N 3.29Å; F304-S306 VanDerWaalsContact C-N 3.29Å; F304-S306 PolarHBondContact O-N 2.82Å; F304-L307 WeakPolarHBondContact O-CB 3.43Å; F304-L307 PolarHBondContact O-N 2.79Å; F304-L307 VanDerWaalsContact O-N 3.11Å; F304-L447 HydrophobicContact CZ-CD1 4.36Å; F304-L447 WeakPolarHBondContact O-CD2 3.36Å
305	F	97.6	Very high	93.7	Very high	5 Å²	5	36.7 Å²	36.7	2%	0.022	19%	0.185	C	C	.	.	H	α-helix	trans	-71.1	-24.3	-177.2	-76	-70.7	0	0	0	113.1	F141 P142 V143 F301 Y426 Y448 V451 W477	F141-F305 HydrophobicContact CE2-CB 4.04Å; F141-F305 AromaticContact CE2-CD1 3.9Å; F141-F305 HydrophobicContact CE2-CD1 3.9Å; F141-F305 HydrophobicContact CE2-CD2 4.13Å; F141-F305 HydrophobicContact CE2-CE1 4.4Å; F141-F305 AromaticContact CE2-CG 3.75Å; F141-F305 HydrophobicContact CE2-CG 3.75Å; F141-F305 HydrophobicContact CZ-CD2 4.46Å; P142-F305 HydrophobicContact CB-CE1 4.15Å; P142-F305 HydrophobicContact CG-CD1 4.36Å; P142-F305 HydrophobicContact CG-CE1 3.9Å; V143-F305 HydrophobicContact CG2-CE2 4.44Å; V143-F305 HydrophobicContact CG2-CZ 4.26Å; F301-F305 HydrophobicContact CD1-CD2 4.22Å; F301-F305 AromaticContact CD2-CD2 3.83Å; F301-F305 HydrophobicContact CD2-CD2 3.83Å; F301-F305 AromaticContact CD2-CE2 3.6Å; F301-F305 HydrophobicContact CD2-CE2 3.6Å; F301-F305 HydrophobicContact CE1-CD2 4.07Å; F301-F305 HydrophobicContact CE1-CE2 4.47Å; F301-F305 AromaticContact CE2-CD2 3.67Å; F301-F305 HydrophobicContact CE2-CD2 3.67Å; F301-F305 AromaticContact CE2-CE2 3.26Å; F301-F305 HydrophobicContact CE2-CE2 3.26Å; F301-F305 HydrophobicContact CE2-CZ 4.32Å; F301-F305 HydrophobicContact CG-CD2 4.12Å; F301-F305 HydrophobicContact CG-CE2 4.35Å; F301-F305 AromaticContact CZ-CD2 3.83Å; F301-F305 HydrophobicContact CZ-CD2 3.83Å; F301-F305 AromaticContact CZ-CE2 3.78Å; F301-F305 HydrophobicContact CZ-CE2 3.78Å; F301-F305 WeakPolarHBondContact O-CD2 3.37Å; F301-F305 PolarHBondContact O-N 2.98Å; F305-Y426 HydrophobicContact CB-CE2 3.81Å; F305-Y426 PolarHBondContact O-OH 2.7Å; F305-Y448 HydrophobicContact CB-CE1 4.04Å; F305-Y448 HydrophobicContact CD1-CD1 4.2Å; F305-Y448 AromaticContact CD1-CE1 3.77Å; F305-Y448 HydrophobicContact CD1-CE1 3.77Å; F305-Y448 HydrophobicContact CG-CE1 4.39Å; F305-Y448 VanDerWaalsContact O-CE1 3.24Å; F305-Y448 WeakPolarHBondContact O-CE1 3.36Å; F305-Y448 PolarHBondContact O-OH 3.31Å; F305-V451 HydrophobicContact CE1-CG1 4.33Å; F305-W477 AromaticContact CZ-CH2 3.89Å; F305-W477 HydrophobicContact CZ-CH2 3.89Å; F305-W477 HydrophobicContact CZ-CZ2 4.42Å
306	S	95.8	Very high	93.3	Very high	1 Å²	1	38.1 Å²	38.1	1%	0.007	19%	0.193	C	C	.	.	T	Hydrogen-bonded Turn	trans	-95.3	11	172	70	0	0	0	0	113.7	T302 Y303 F304 V309 S310	T302-S306 VanDerWaalsContact O-CB 3.25Å; T302-S306 WeakPolarHBondContact O-CB 3.24Å; T302-S306 PolarHBondContact O-N 2.98Å; T302-S306 PolarHBondContact O-OG 3.41Å; Y303-S306 CarbonylContact O-C 3.6Å; F304-S306 VanDerWaalsContact C-N 3.29Å; F304-S306 PolarHBondContact O-N 2.82Å; S306-V309 CarbonylContact O-C 3.59Å; S306-V309 WeakPolarHBondContact O-CB 3.25Å; S306-V309 PolarHBondContact O-N 3.41Å; S306-S310 WeakPolarHBondContact CB-OG 3.49Å; S306-S310 VanDerWaalsContact O-CB 3.25Å; S306-S310 WeakPolarHBondContact O-CB 3.25Å; S306-S310 PolarHBondContact O-N 3.01Å; S306-S310 PolarHBondContact O-OG 3.2Å; S306-S310 PolarHBondContact OG-OG 2.64Å
307	L	94.6	Very high	93	Very high	58 Å²	58	41.4 Å²	41.4	30%	0.304	21%	0.212	S	C	.	.	H	α-helix	trans	-53	-48	-169.2	-176.1	75.2	0	0	0	113.3	Y303 F304 V309 S310 L311	Y303-L307 HydrophobicContact CD1-CD1 4.25Å; Y303-L307 HydrophobicContact CE1-CD1 3.57Å; Y303-L307 HydrophobicContact CE2-CD1 4.45Å; Y303-L307 VanDerWaalsContact O-CA 3.26Å; Y303-L307 WeakPolarHBondContact O-CA 3.38Å; Y303-L307 WeakPolarHBondContact O-CB 3.31Å; Y303-L307 PolarHBondContact O-N 2.63Å; F304-L307 WeakPolarHBondContact O-CB 3.43Å; F304-L307 PolarHBondContact O-N 2.79Å; F304-L307 VanDerWaalsContact O-N 3.11Å; L307-V309 PolarHBondContact O-N 2.99Å; L307-S310 PolarHBondContact O-N 2.78Å; L307-L311 HydrophobicContact CD1-CB 4.02Å; L307-L311 HydrophobicContact CD1-CD1 4.41Å; L307-L311 HydrophobicContact CD1-CD2 4.28Å; L307-L311 HydrophobicContact CD1-CG 4.47Å; L307-L311 HydrophobicContact CG-CB 4.3Å; L307-L311 HydrophobicContact CG-CD2 4.41Å; L307-L311 WeakPolarHBondContact O-CA 2.97Å; L307-L311 WeakPolarHBondContact O-CB 3.2Å; L307-L311 PolarHBondContact O-N 2.9Å
308	P	93.9	Very high	92.8	Very high	34 Å²	34	44.9 Å²	44.9	22%	0.221	23%	0.225	C	C	.	.	H	α-helix	trans	-64.1	-26.4	-178.6	-25.7	39.9	0	0	0	113.6	R440 G443 E444 L447	P308-R440 WeakPolarHBondContact CB-O 3.49Å; P308-R440 WeakPolarHBondContact O-CB 3.41Å; P308-R440 VanDerWaalsContact O-CD 3.3Å; P308-R440 WeakPolarHBondContact O-CD 3.22Å; P308-R440 VanDerWaalsContact O-CG 3.26Å; P308-R440 WeakPolarHBondContact O-CG 3.3Å; P308-G443 VanDerWaalsContact CG-C 3.49Å; P308-E444 HydrophobicContact CB-CB 4.39Å; P308-E444 HydrophobicContact CG-CB 4.45Å; P308-L447 HydrophobicContact CG-CB 4.33Å; P308-L447 HydrophobicContact CG-CD2 4.17Å
309	V	90.8	Very high	92.6	Very high	1 Å²	1	46.1 Å²	46.1	1%	0.006	23%	0.23	C	C	.	.	H	α-helix	trans	-87.8	-40.2	-179.9	178.1	0	0	0	0	110.7	S306 L307 M433 S436 R440 L441 E444	S306-V309 CarbonylContact O-C 3.59Å; S306-V309 WeakPolarHBondContact O-CB 3.25Å; S306-V309 PolarHBondContact O-N 3.41Å; L307-V309 PolarHBondContact O-N 2.99Å; V309-M433 HydrophobicContact CG1-CE 3.68Å; V309-S436 WeakPolarHBondContact CG1-OG 2.98Å; V309-R440 PolarHBondContact O-NH1 3.24Å; V309-L441 HydrophobicContact CG2-CD2 4.44Å; V309-E444 HydrophobicContact CG2-CB 3.99Å; V309-E444 HydrophobicContact CG2-CG 4.36Å
310	S	86.8	Confident	92.4	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-91.7	-23.7	-171.2	-66.3	0	0	0	0	114.1	S306 L307 R315 N387	S306-S310 WeakPolarHBondContact CB-OG 3.49Å; S306-S310 VanDerWaalsContact O-CB 3.25Å; S306-S310 WeakPolarHBondContact O-CB 3.25Å; S306-S310 PolarHBondContact O-N 3.01Å; S306-S310 PolarHBondContact O-OG 3.2Å; S306-S310 PolarHBondContact OG-OG 2.64Å; L307-S310 PolarHBondContact O-N 2.78Å; S310-R315 VanDerWaalsContact O-CD 3.31Å; S310-R315 WeakPolarHBondContact O-CD 3.44Å; S310-N387 PolarHBondContact O-ND2 3.13Å
311	L	83.3	Confident	92.3	Very high	86 Å²	86	49.9 Å²	49.9	45%	0.45	25%	0.252	S	S	.	.			trans	-76.9	124.1	178.5	-174.2	66.4	0	0	0	110.3	Y303 L307	Y303-L311 WeakPolarHBondContact OH-CD1 3.3Å; L307-L311 HydrophobicContact CD1-CB 4.02Å; L307-L311 HydrophobicContact CD1-CD1 4.41Å; L307-L311 HydrophobicContact CD1-CD2 4.28Å; L307-L311 HydrophobicContact CD1-CG 4.47Å; L307-L311 HydrophobicContact CG-CB 4.3Å; L307-L311 HydrophobicContact CG-CD2 4.41Å; L307-L311 WeakPolarHBondContact O-CA 2.97Å; L307-L311 WeakPolarHBondContact O-CB 3.2Å; L307-L311 PolarHBondContact O-N 2.9Å
312	C	84.1	Confident	92	Very high	34 Å²	34	50.3 Å²	50.3	23%	0.23	26%	0.258	C	S	.	.			trans	-157.9	132.4	173.1	-176.7	0	0	0	0	108.7	H314 R315 T316	C312-H314 PolarHBondContact O-N 3.35Å; C312-H314 VanDerWaalsContact O-N 3.16Å; C312-R315 HydrophobicContact CB-CB 4.42Å; C312-R315 HydrophobicContact CB-CG 4.21Å; C312-R315 WeakPolarHBondContact O-CA 3.24Å; C312-R315 WeakPolarHBondContact O-CB 3.3Å; C312-R315 PolarHBondContact O-N 2.79Å; C312-T316 PolarHBondContact O-N 3.16Å
313	L	86.9	Confident	91.9	Very high	128 Å²	128	53.5 Å²	53.5	67%	0.67	27%	0.274	S	S	*	.	H	α-helix	trans	-53.1	-36.8	176.3	-177.6	64.4	0	0	0	111.9	R315 T316 L317	L313-R315 VanDerWaalsContact C-N 3.3Å; L313-R315 PolarHBondContact O-N 3.3Å; L313-T316 WeakPolarHBondContact CA-OG1 3.12Å; L313-T316 PolarHBondContact O-N 3.35Å; L313-T316 PolarHBondContact O-OG1 3.19Å; L313-L317 HydrophobicContact CD1-CG 4.48Å; L313-L317 HydrophobicContact CG-CD1 4.13Å; L313-L317 HydrophobicContact CG-CG 4.44Å; L313-L317 WeakPolarHBondContact O-CG 3.24Å; L313-L317 PolarHBondContact O-N 3.37Å
314	H	87.5	Confident	91.8	Very high	115 Å²	115	59.1 Å²	59.1	53%	0.532	30%	0.299	S	S	.	.	H	α-helix	trans	-62.4	-35.7	175.8	-175.7	72.7	0	0	0	113	C312 R318	C312-H314 PolarHBondContact O-N 3.35Å; C312-H314 VanDerWaalsContact O-N 3.16Å; H314-R318 PolarHBondContact CD2-NE 2.73Å; H314-R318 WeakPolarHBondContact NE2-CD 3.21Å; H314-R318 PolarHBondContact NE2-NE 3.28Å; H314-R318 WeakPolarHBondContact O-CB 3.43Å; H314-R318 WeakPolarHBondContact O-CG 3.24Å; H314-R318 PolarHBondContact O-N 2.01Å
315	R	87.9	Confident	91.7	Very high	44 Å²	44	63.8 Å²	63.8	17%	0.166	31%	0.314	C	S	.	.	H	α-helix	trans	-70.7	-39.4	176.9	-73	-177	174.3	-161.2	-2.8	111.5	S310 C312 L313 R318 F319 W386 N387 T391	S310-R315 VanDerWaalsContact O-CD 3.31Å; S310-R315 WeakPolarHBondContact O-CD 3.44Å; C312-R315 HydrophobicContact CB-CB 4.42Å; C312-R315 HydrophobicContact CB-CG 4.21Å; C312-R315 WeakPolarHBondContact O-CA 3.24Å; C312-R315 WeakPolarHBondContact O-CB 3.3Å; C312-R315 PolarHBondContact O-N 2.79Å; L313-R315 VanDerWaalsContact C-N 3.3Å; L313-R315 PolarHBondContact O-N 3.3Å; R315-R318 PolarHBondContact O-N 2.81Å; R315-F319 PolarHBondContact O-N 2.8Å; R315-W386 WeakPolarHBondContact O-CZ3 3.43Å; R315-N387 PolarHBondContact NH1-OD1 2.87Å; R315-T391 PolarHBondContact NH1-OG1 3.3Å; R315-T391 PolarHBondContact NH2-OG1 3.4Å
316	T	89.3	Confident	91.5	Very high	47 Å²	47	68.2 Å²	68.2	29%	0.288	34%	0.335	S	S	.	.	H	α-helix	trans	-67.6	-41.6	177.6	55.5	0	0	0	0	111.5	C312 L313 R318 F319 S320 F383	C312-T316 PolarHBondContact O-N 3.16Å; L313-T316 WeakPolarHBondContact CA-OG1 3.12Å; L313-T316 PolarHBondContact O-N 3.35Å; L313-T316 PolarHBondContact O-OG1 3.19Å; T316-R318 PolarHBondContact O-N 3.04Å; T316-F319 WeakPolarHBondContact O-CB 2.88Å; T316-F319 PolarHBondContact O-N 3.17Å; T316-S320 PolarHBondContact O-N 3.35Å; T316-F383 HydrophobicContact CG2-CE2 4.27Å; T316-F383 HydrophobicContact CG2-CZ 3.96Å
317	L	92.9	Very high	91.5	Very high	93 Å²	93	71.6 Å²	71.6	49%	0.487	36%	0.356	S	S	.	.	H	α-helix	trans	-62	-42	173.6	-69.2	174.2	0	0	0	112.1	L313 F319 S320 N321	L313-L317 HydrophobicContact CD1-CG 4.48Å; L313-L317 HydrophobicContact CG-CD1 4.13Å; L313-L317 HydrophobicContact CG-CG 4.44Å; L313-L317 WeakPolarHBondContact O-CG 3.24Å; L313-L317 PolarHBondContact O-N 3.37Å; L317-F319 VanDerWaalsContact C-N 3.33Å; L317-F319 PolarHBondContact O-N 2.76Å; L317-S320 PolarHBondContact O-N 2.72Å; L317-N321 PolarHBondContact O-N 2.85Å
318	R	92.6	Very high	91.5	Very high	82 Å²	82	74 Å²	74	31%	0.309	37%	0.374	S	S	.	.	H	α-helix	trans	-64.3	-36.4	175.1	-77.5	-166.9	-57.6	152.9	9.7	112.9	H314 R315 T316 N321 A322 W386 E390	H314-R318 PolarHBondContact CD2-NE 2.73Å; H314-R318 WeakPolarHBondContact NE2-CD 3.21Å; H314-R318 PolarHBondContact NE2-NE 3.28Å; H314-R318 WeakPolarHBondContact O-CB 3.43Å; H314-R318 WeakPolarHBondContact O-CG 3.24Å; H314-R318 PolarHBondContact O-N 2.01Å; R315-R318 PolarHBondContact O-N 2.81Å; T316-R318 PolarHBondContact O-N 3.04Å; R318-N321 PolarHBondContact O-N 3.31Å; R318-A322 WeakPolarHBondContact O-CB 2.93Å; R318-A322 PolarHBondContact O-N 3.12Å; R318-W386 HydrophobicContact CB-CH2 3.83Å; R318-W386 HydrophobicContact CB-CZ2 4.34Å; R318-E390 IonicContact CZ-OE1 2.74Å; R318-E390 IonicContact NH1-OE1 3.64Å; R318-E390 PolarHBondContact NH1-OE1 3.38Å; R318-E390 IonicContact NH2-OE1 3.95Å; R318-E390 PolarHBondContact NH2-OE1 3.09Å
319	F	94.5	Very high	91.5	Very high	26 Å²	26	78.4 Å²	78.4	11%	0.114	39%	0.389	C	S	.	.	H	α-helix	trans	-64	-45.7	173.2	179.1	-114.2	0	0	0	111.4	R315 T316 L317 N321 A322 L323 F330 I382 F383 W386	R315-F319 PolarHBondContact O-N 2.8Å; T316-F319 WeakPolarHBondContact O-CB 2.88Å; T316-F319 PolarHBondContact O-N 3.17Å; L317-F319 VanDerWaalsContact C-N 3.33Å; L317-F319 PolarHBondContact O-N 2.76Å; F319-N321 VanDerWaalsContact C-N 3.33Å; F319-N321 PolarHBondContact O-N 3.33Å; F319-A322 WeakPolarHBondContact O-CB 3.18Å; F319-A322 PolarHBondContact O-N 3.25Å; F319-A322 VanDerWaalsContact O-N 3.1Å; F319-L323 HydrophobicContact CD1-CD1 3.83Å; F319-L323 HydrophobicContact CD1-CG 4.46Å; F319-L323 HydrophobicContact CE1-CD1 3.44Å; F319-L323 VanDerWaalsContact CE1-CD1 3.44Å; F319-L323 HydrophobicContact CE1-CG 4.12Å; F319-L323 HydrophobicContact CE2-CD1 4.45Å; F319-L323 HydrophobicContact CE2-CD2 4.46Å; F319-L323 HydrophobicContact CE2-CG 4.25Å; F319-L323 HydrophobicContact CZ-CD1 3.79Å; F319-L323 HydrophobicContact CZ-CD2 4.12Å; F319-L323 HydrophobicContact CZ-CG 4.01Å; F319-L323 WeakPolarHBondContact O-CG 3.22Å; F319-L323 PolarHBondContact O-N 3.05Å; F319-F330 AromaticContact CE2-CE1 3.82Å; F319-F330 HydrophobicContact CE2-CE1 3.82Å; F319-F330 HydrophobicContact CE2-CZ 4.18Å; F319-I382 HydrophobicContact CE2-CG2 4.34Å; F319-I382 HydrophobicContact CZ-CG2 4.21Å; F319-F383 HydrophobicContact CB-CD2 4.23Å; F319-F383 HydrophobicContact CB-CE2 4.2Å; F319-F383 AromaticContact CD1-CD2 3.44Å; F319-F383 HydrophobicContact CD1-CD2 3.44Å; F319-F383 VanDerWaalsContact CD1-CD2 3.44Å; F319-F383 HydrophobicContact CD1-CE2 4.07Å; F319-F383 HydrophobicContact CD1-CG 4.41Å; F319-F383 HydrophobicContact CD2-CD2 4.22Å; F319-F383 HydrophobicContact CE1-CB 3.95Å; F319-F383 AromaticContact CE1-CD2 3.69Å; F319-F383 HydrophobicContact CE1-CD2 3.69Å; F319-F383 HydrophobicContact CE1-CG 4.26Å; F319-F383 HydrophobicContact CE2-CD2 4.45Å; F319-F383 AromaticContact CG-CD2 3.7Å; F319-F383 HydrophobicContact CG-CD2 3.7Å; F319-F383 HydrophobicContact CG-CE2 4.18Å; F319-F383 HydrophobicContact CZ-CB 3.99Å; F319-F383 HydrophobicContact CZ-CD2 4.21Å; F319-W386 HydrophobicContact CB-CD2 4.27Å; F319-W386 HydrophobicContact CB-CE3 3.84Å; F319-W386 HydrophobicContact CB-CH2 4.07Å; F319-W386 HydrophobicContact CB-CZ2 4.45Å; F319-W386 HydrophobicContact CB-CZ3 3.74Å; F319-W386 HydrophobicContact CD2-CB 3.99Å; F319-W386 AromaticContact CD2-CD2 3.58Å; F319-W386 HydrophobicContact CD2-CD2 3.58Å; F319-W386 AromaticContact CD2-CE3 3.82Å; F319-W386 HydrophobicContact CD2-CE3 3.82Å; F319-W386 AromaticContact CD2-CG 3.63Å; F319-W386 HydrophobicContact CD2-CG 3.63Å; F319-W386 HydrophobicContact CE2-CB 3.94Å; F319-W386 HydrophobicContact CE2-CD2 4.41Å; F319-W386 HydrophobicContact CE2-CG 4Å; F319-W386 HydrophobicContact CG-CD2 4.35Å; F319-W386 HydrophobicContact CG-CE3 4.19Å
320	S	94.5	Very high	91.7	Very high	47 Å²	47	79 Å²	79	33%	0.329	39%	0.392	S	S	.	.	H	α-helix	trans	-58.6	-44.1	175	-175.5	0	0	0	0	111.9	T316 L317 A322 L323 K324	T316-S320 PolarHBondContact O-N 3.35Å; L317-S320 PolarHBondContact O-N 2.72Å; S320-A322 VanDerWaalsContact C-N 3.35Å; S320-A322 PolarHBondContact O-N 2.98Å; S320-L323 WeakPolarHBondContact O-CB 3.17Å; S320-L323 PolarHBondContact O-N 3.25Å; S320-K324 WeakPolarHBondContact O-CG 3.47Å; S320-K324 PolarHBondContact O-N 2.93Å
321	N	94.4	Very high	92.2	Very high	96 Å²	96	82.2 Å²	82.2	51%	0.513	42%	0.415	S	S	.	.	H	α-helix	trans	-65.2	-36.7	174.8	-71.3	-14.7	0	0	0	112.5	L317 R318 F319 K324 R325	L317-N321 PolarHBondContact O-N 2.85Å; R318-N321 PolarHBondContact O-N 3.31Å; F319-N321 VanDerWaalsContact C-N 3.33Å; F319-N321 PolarHBondContact O-N 3.33Å; N321-K324 PolarHBondContact O-N 3.21Å; N321-R325 VanDerWaalsContact O-CB 3.3Å; N321-R325 WeakPolarHBondContact O-CB 3.4Å; N321-R325 PolarHBondContact O-N 3.21Å
322	A	93.4	Very high	92.8	Very high	20 Å²	20	82.1 Å²	82.1	17%	0.165	42%	0.417	C	S	.	.	H	α-helix	trans	-65.9	-41.9	175.6	0	0	0	0	0	111.8	R318 F319 S320 K324 R325 H326 F330	R318-A322 WeakPolarHBondContact O-CB 2.93Å; R318-A322 PolarHBondContact O-N 3.12Å; F319-A322 WeakPolarHBondContact O-CB 3.18Å; F319-A322 PolarHBondContact O-N 3.25Å; F319-A322 VanDerWaalsContact O-N 3.1Å; S320-A322 VanDerWaalsContact C-N 3.35Å; S320-A322 PolarHBondContact O-N 2.98Å; A322-K324 VanDerWaalsContact C-N 3.34Å; A322-K324 PolarHBondContact O-N 3.37Å; A322-R325 PolarHBondContact O-N 3.29Å; A322-H326 PolarHBondContact O-N 2.94Å; A322-F330 HydrophobicContact CB-CE2 4.04Å; A322-F330 HydrophobicContact CB-CZ 4.21Å; A322-F330 WeakPolarHBondContact O-CE2 3.31Å
323	L	94.6	Very high	93.4	Very high	67 Å²	67	83.2 Å²	83.2	35%	0.351	42%	0.421	S	S	.	.	H	α-helix	trans	-58	-46.2	173.8	-75.8	169.1	0	0	0	111.3	F319 S320 F330	F319-L323 HydrophobicContact CD1-CD1 3.83Å; F319-L323 HydrophobicContact CD1-CG 4.46Å; F319-L323 HydrophobicContact CE1-CD1 3.44Å; F319-L323 VanDerWaalsContact CE1-CD1 3.44Å; F319-L323 HydrophobicContact CE1-CG 4.12Å; F319-L323 HydrophobicContact CE2-CD1 4.45Å; F319-L323 HydrophobicContact CE2-CD2 4.46Å; F319-L323 HydrophobicContact CE2-CG 4.25Å; F319-L323 HydrophobicContact CZ-CD1 3.79Å; F319-L323 HydrophobicContact CZ-CD2 4.12Å; F319-L323 HydrophobicContact CZ-CG 4.01Å; F319-L323 WeakPolarHBondContact O-CG 3.22Å; F319-L323 PolarHBondContact O-N 3.05Å; S320-L323 WeakPolarHBondContact O-CB 3.17Å; S320-L323 PolarHBondContact O-N 3.25Å; L323-F330 HydrophobicContact CD2-CB 3.79Å; L323-F330 HydrophobicContact CD2-CD1 3.74Å; L323-F330 HydrophobicContact CD2-CD2 3.82Å; L323-F330 HydrophobicContact CD2-CE1 4.24Å; L323-F330 HydrophobicContact CD2-CE2 4.31Å; L323-F330 HydrophobicContact CD2-CG 3.51Å; L323-F330 HydrophobicContact CD2-CZ 4.49Å; L323-F330 HydrophobicContact CG-CD2 4.46Å
324	K	95.4	Very high	93.9	Very high	158 Å²	158	79.4 Å²	79.4	69%	0.687	40%	0.403	S	S	*	.	H	α-helix	trans	-66	-38	177.9	-69.6	178	-178	-176.2	0	112.9	S320 N321 A322	S320-K324 WeakPolarHBondContact O-CG 3.47Å; S320-K324 PolarHBondContact O-N 2.93Å; N321-K324 PolarHBondContact O-N 3.21Å; A322-K324 VanDerWaalsContact C-N 3.34Å; A322-K324 PolarHBondContact O-N 3.37Å
325	R	94.8	Very high	94.4	Very high	198 Å²	198	79.5 Å²	79.5	75%	0.747	41%	0.406	S	S	*	.	H	α-helix	trans	-78.5	-30.5	-176.5	-169.2	175.3	-177.8	151.1	1.4	113.3	N321 A322 P327	N321-R325 VanDerWaalsContact O-CB 3.3Å; N321-R325 WeakPolarHBondContact O-CB 3.4Å; N321-R325 PolarHBondContact O-N 3.21Å; A322-R325 PolarHBondContact O-N 3.29Å; R325-P327 VanDerWaalsContact C-CD 3.44Å
326	H	93.4	Very high	94.9	Very high	98 Å²	98	80.7 Å²	80.7	45%	0.454	42%	0.418	S	S	.	.			trans	-130.1	56.4	-174.9	-59.1	-63.2	0	0	0	112.5	A322 V328 F329 F330	A322-H326 PolarHBondContact O-N 2.94Å; H326-V328 PolarHBondContact O-N 3.4Å; H326-F329 HydrophobicContact CB-CB 4.16Å; H326-F329 PolarHBondContact O-N 3.17Å; H326-F330 HydrophobicContact CB-CD2 4.42Å; H326-F330 HydrophobicContact CB-CE2 4.49Å; H326-F330 WeakPolarHBondContact O-CD2 3.46Å; H326-F330 PolarHBondContact O-N 3.44Å
327	P	95.3	Very high	95.3	Very high	71 Å²	71	78.7 Å²	78.7	46%	0.461	41%	0.406	S	S	.	.	H	α-helix	trans	-61.6	-42.2	-173.1	25.1	-34.2	0	0	0	112.1	R325 F329 F330 S331	R325-P327 VanDerWaalsContact C-CD 3.44Å; P327-F329 VanDerWaalsContact C-N 3.34Å; P327-F329 PolarHBondContact O-N 2.85Å; P327-F330 PolarHBondContact O-N 3.36Å; P327-S331 WeakPolarHBondContact O-CB 3.08Å; P327-S331 PolarHBondContact O-N 2.87Å; P327-S331 PolarHBondContact O-OG 2.82Å; P327-S331 VanDerWaalsContact O-OG 3.04Å
328	V	95	Very high	95.6	Very high	110 Å²	110	77.2 Å²	77.2	67%	0.667	40%	0.398	S	S	*	.	H	α-helix	trans	-58.8	-44.1	179	179.4	0	0	0	0	111.7	H326 S331 V332	H326-V328 PolarHBondContact O-N 3.4Å; V328-S331 PolarHBondContact O-N 3.44Å; V328-V332 WeakPolarHBondContact O-CG2 3.38Å; V328-V332 PolarHBondContact O-N 3.41Å
329	F	93.3	Very high	95.9	Very high	125 Å²	125	78.3 Å²	78.3	55%	0.548	41%	0.405	S	S	.	.	H	α-helix	trans	-61.4	-47.2	178.8	171.6	-97.7	0	0	0	111.4	H326 P327 V332 L333	H326-F329 HydrophobicContact CB-CB 4.16Å; H326-F329 PolarHBondContact O-N 3.17Å; P327-F329 VanDerWaalsContact C-N 3.34Å; P327-F329 PolarHBondContact O-N 2.85Å; F329-V332 PolarHBondContact O-N 2.98Å; F329-L333 HydrophobicContact CE1-CD2 4.2Å; F329-L333 WeakPolarHBondContact O-CB 3.21Å; F329-L333 PolarHBondContact O-N 3.45Å
330	F	95.7	Very high	96	Very high	14 Å²	14	78.5 Å²	78.5	6%	0.061	41%	0.407	C	S	.	.	H	α-helix	trans	-70.9	-31.2	179.8	-76.5	-76.2	0	0	0	112.9	F319 A322 L323 H326 P327 L333 T334 I382	F319-F330 AromaticContact CE2-CE1 3.82Å; F319-F330 HydrophobicContact CE2-CE1 3.82Å; F319-F330 HydrophobicContact CE2-CZ 4.18Å; A322-F330 HydrophobicContact CB-CE2 4.04Å; A322-F330 HydrophobicContact CB-CZ 4.21Å; A322-F330 WeakPolarHBondContact O-CE2 3.31Å; L323-F330 HydrophobicContact CD2-CB 3.79Å; L323-F330 HydrophobicContact CD2-CD1 3.74Å; L323-F330 HydrophobicContact CD2-CD2 3.82Å; L323-F330 HydrophobicContact CD2-CE1 4.24Å; L323-F330 HydrophobicContact CD2-CE2 4.31Å; L323-F330 HydrophobicContact CD2-CG 3.51Å; L323-F330 HydrophobicContact CD2-CZ 4.49Å; L323-F330 HydrophobicContact CG-CD2 4.46Å; H326-F330 HydrophobicContact CB-CD2 4.42Å; H326-F330 HydrophobicContact CB-CE2 4.49Å; H326-F330 WeakPolarHBondContact O-CD2 3.46Å; H326-F330 PolarHBondContact O-N 3.44Å; P327-F330 PolarHBondContact O-N 3.36Å; F330-L333 HydrophobicContact CD1-CD2 4.22Å; F330-L333 HydrophobicContact CE1-CD2 4.49Å; F330-T334 WeakPolarHBondContact O-CB 3.3Å; F330-T334 PolarHBondContact O-N 3.38Å; F330-T334 PolarHBondContact O-OG1 3.28Å; F330-I382 HydrophobicContact CD1-CG2 3.87Å; F330-I382 HydrophobicContact CE1-CG2 4.04Å
331	S	96.6	Very high	96.2	Very high	68 Å²	68	76.4 Å²	76.4	48%	0.476	39%	0.393	S	S	.	.	H	α-helix	trans	-63.8	-48.8	171.2	-64.6	0	0	0	0	111.4	P327 V328 L333 T334 I335	P327-S331 WeakPolarHBondContact O-CB 3.08Å; P327-S331 PolarHBondContact O-N 2.87Å; P327-S331 PolarHBondContact O-OG 2.82Å; P327-S331 VanDerWaalsContact O-OG 3.04Å; V328-S331 PolarHBondContact O-N 3.44Å; S331-L333 PolarHBondContact O-N 3.4Å; S331-T334 WeakPolarHBondContact O-CB 3.46Å; S331-T334 PolarHBondContact O-N 3.31Å; S331-I335 WeakPolarHBondContact O-CG1 3.44Å; S331-I335 PolarHBondContact O-N 3.21Å
332	V	96.8	Very high	96.3	Very high	83 Å²	83	79.1 Å²	79.1	50%	0.503	40%	0.395	S	S	.	.	H	α-helix	trans	-60.6	-45.7	175.4	171.3	0	0	0	0	110.8	V328 F329 T334 I335 V336	V328-V332 WeakPolarHBondContact O-CG2 3.38Å; V328-V332 PolarHBondContact O-N 3.41Å; F329-V332 PolarHBondContact O-N 2.98Å; V332-T334 VanDerWaalsContact C-N 3.26Å; V332-T334 PolarHBondContact O-N 3.05Å; V332-I335 PolarHBondContact O-N 3.07Å; V332-V336 HydrophobicContact CG1-CG2 4.33Å; V332-V336 WeakPolarHBondContact O-CG2 3.5Å; V332-V336 PolarHBondContact O-N 3.09Å
333	L	96.3	Very high	96.4	Very high	58 Å²	58	83.9 Å²	83.9	30%	0.304	41%	0.413	S	S	.	.	H	α-helix	trans	-59.1	-38.6	177	-178.7	61.6	0	0	0	111.9	F329 F330 S331 S337 I382	F329-L333 HydrophobicContact CE1-CD2 4.2Å; F329-L333 WeakPolarHBondContact O-CB 3.21Å; F329-L333 PolarHBondContact O-N 3.45Å; F330-L333 HydrophobicContact CD1-CD2 4.22Å; F330-L333 HydrophobicContact CE1-CD2 4.49Å; S331-L333 PolarHBondContact O-N 3.4Å; L333-S337 VanDerWaalsContact O-CB 3.26Å; L333-S337 WeakPolarHBondContact O-CB 3.42Å; L333-S337 PolarHBondContact O-N 3.39Å; L333-S337 PolarHBondContact O-OG 2.79Å; L333-I382 HydrophobicContact CD2-CG1 4.31Å; L333-I382 HydrophobicContact CD2-CG2 3.95Å; L333-I382 HydrophobicContact CG-CD1 4.41Å; L333-I382 HydrophobicContact CG-CG1 4.31Å
334	T	97.9	Very high	96.6	Very high	48 Å²	48	82.7 Å²	82.7	29%	0.294	41%	0.405	S	S	.	.	H	α-helix	trans	-66.2	-46.6	176.2	-57.9	0	0	0	0	111.3	F330 S331 V332 V336 S337 L338 V378 I382	F330-T334 WeakPolarHBondContact O-CB 3.3Å; F330-T334 PolarHBondContact O-N 3.38Å; F330-T334 PolarHBondContact O-OG1 3.28Å; S331-T334 WeakPolarHBondContact O-CB 3.46Å; S331-T334 PolarHBondContact O-N 3.31Å; V332-T334 VanDerWaalsContact C-N 3.26Å; V332-T334 PolarHBondContact O-N 3.05Å; T334-V336 PolarHBondContact O-N 2.84Å; T334-S337 PolarHBondContact O-N 3.45Å; T334-L338 HydrophobicContact CG2-CD1 3.97Å; T334-L338 HydrophobicContact CG2-CG 4.37Å; T334-L338 WeakPolarHBondContact O-CB 3.38Å; T334-L338 VanDerWaalsContact O-CG 3.27Å; T334-L338 WeakPolarHBondContact O-CG 3.33Å; T334-L338 PolarHBondContact O-N 2.95Å; T334-V378 HydrophobicContact CG2-CG1 4.13Å; T334-I382 HydrophobicContact CG2-CD1 4.44Å; T334-I382 WeakPolarHBondContact OG1-CD1 3.33Å
335	I	98.3	Very high	96.5	Very high	117 Å²	117	76.3 Å²	76.3	60%	0.6	38%	0.379	S	S	*	.	H	α-helix	trans	-60	-47.4	177.7	-67.3	165.2	0	0	0	110.6	S331 V332 S337 L338 F339	S331-I335 WeakPolarHBondContact O-CG1 3.44Å; S331-I335 PolarHBondContact O-N 3.21Å; V332-I335 PolarHBondContact O-N 3.07Å; I335-S337 PolarHBondContact O-N 3.37Å; I335-L338 PolarHBondContact O-N 2.72Å; I335-F339 PolarHBondContact O-N 2.92Å
336	V	98.1	Very high	96.5	Very high	69 Å²	69	70.6 Å²	70.6	42%	0.418	36%	0.358	S	S	.	.	H	α-helix	trans	-61.6	-44.6	176.8	172.8	0	0	0	0	110.6	V332 T334 L338 F339 L340	V332-V336 HydrophobicContact CG1-CG2 4.33Å; V332-V336 WeakPolarHBondContact O-CG2 3.5Å; V332-V336 PolarHBondContact O-N 3.09Å; T334-V336 PolarHBondContact O-N 2.84Å; V336-L338 PolarHBondContact O-N 3.48Å; V336-F339 WeakPolarHBondContact O-CB 3.41Å; V336-F339 PolarHBondContact O-N 3.06Å; V336-L340 HydrophobicContact CG1-CD1 4.05Å; V336-L340 HydrophobicContact CG1-CG 4.32Å; V336-L340 VanDerWaalsContact O-CG 3.3Å; V336-L340 WeakPolarHBondContact O-CG 3.38Å; V336-L340 PolarHBondContact O-N 3.13Å
337	S	98.2	Very high	96.4	Very high	4 Å²	4	68.7 Å²	68.7	3%	0.028	35%	0.353	C	S	.	.	H	α-helix	trans	-63.5	-40.7	178.7	-59.1	0	0	0	0	112	L333 T334 I335 L340 V341	L333-S337 VanDerWaalsContact O-CB 3.26Å; L333-S337 WeakPolarHBondContact O-CB 3.42Å; L333-S337 PolarHBondContact O-N 3.39Å; L333-S337 PolarHBondContact O-OG 2.79Å; T334-S337 PolarHBondContact O-N 3.45Å; I335-S337 PolarHBondContact O-N 3.37Å; S337-L340 PolarHBondContact O-N 3.31Å; S337-V341 WeakPolarHBondContact O-CB 3.47Å; S337-V341 VanDerWaalsContact O-CG2 3.32Å; S337-V341 WeakPolarHBondContact O-CG2 3.33Å; S337-V341 PolarHBondContact O-N 2.94Å
338	L	98.3	Very high	96.3	Very high	63 Å²	63	65.7 Å²	65.7	33%	0.33	33%	0.333	S	S	.	.	H	α-helix	trans	-62.5	-43.9	174.6	-73.7	167.2	0	0	0	111.4	T334 I335 V336 V341 W342 F375 V378	T334-L338 HydrophobicContact CG2-CD1 3.97Å; T334-L338 HydrophobicContact CG2-CG 4.37Å; T334-L338 WeakPolarHBondContact O-CB 3.38Å; T334-L338 VanDerWaalsContact O-CG 3.27Å; T334-L338 WeakPolarHBondContact O-CG 3.33Å; T334-L338 PolarHBondContact O-N 2.95Å; I335-L338 PolarHBondContact O-N 2.72Å; V336-L338 PolarHBondContact O-N 3.48Å; L338-V341 PolarHBondContact O-N 2.89Å; L338-W342 VanDerWaalsContact O-CB 3.31Å; L338-W342 WeakPolarHBondContact O-CB 3.29Å; L338-W342 PolarHBondContact O-N 3.42Å; L338-F375 HydrophobicContact CD2-CB 3.85Å; L338-F375 HydrophobicContact CD2-CD1 3.81Å; L338-F375 HydrophobicContact CD2-CG 4.24Å; L338-V378 HydrophobicContact CD2-CB 4.37Å; L338-V378 HydrophobicContact CD2-CG2 3.9Å; L338-V378 HydrophobicContact CG-CG1 4.48Å; L338-V378 HydrophobicContact CG-CG2 4.38Å
339	F	98.3	Very high	96.2	Very high	105 Å²	105	65.8 Å²	65.8	46%	0.461	32%	0.324	S	S	.	.	H	α-helix	trans	-60.7	-46	175.1	172.9	-101.8	0	0	0	111.6	I335 V336 W342 K343 F344	I335-F339 PolarHBondContact O-N 2.92Å; V336-F339 WeakPolarHBondContact O-CB 3.41Å; V336-F339 PolarHBondContact O-N 3.06Å; F339-W342 HydrophobicContact CD2-CE3 4.12Å; F339-W342 HydrophobicContact CD2-CZ3 4.37Å; F339-W342 HydrophobicContact CE2-CE3 4.27Å; F339-W342 HydrophobicContact CE2-CZ3 4.15Å; F339-W342 PolarHBondContact O-N 2.79Å; F339-K343 HydrophobicContact CE2-CB 4.39Å; F339-K343 HydrophobicContact CZ-CB 4.39Å; F339-K343 HydrophobicContact CZ-CG 4.46Å; F339-K343 WeakPolarHBondContact O-CB 3.38Å; F339-K343 PolarHBondContact O-N 3.17Å; F339-F344 HydrophobicContact CE1-CE2 4.03Å
340	L	98.2	Very high	96.1	Very high	30 Å²	30	64.3 Å²	64.3	16%	0.157	32%	0.316	C	S	.	.	H	α-helix	trans	-62.7	-44.7	178.3	-68.9	177.4	0	0	0	111.7	F292 F296 V336 S337 W342 F344	F292-L340 HydrophobicContact CB-CB 4.29Å; F292-L340 HydrophobicContact CB-CD1 4.31Å; F292-L340 HydrophobicContact CB-CD2 4.08Å; F292-L340 HydrophobicContact CB-CG 4.46Å; F292-L340 HydrophobicContact CD1-CD2 4.26Å; F292-L340 HydrophobicContact CD2-CD2 3.91Å; F292-L340 HydrophobicContact CE2-CD2 4.4Å; F292-L340 HydrophobicContact CG-CD2 3.83Å; F296-L340 HydrophobicContact CE2-CB 4.24Å; F296-L340 HydrophobicContact CZ-CB 4.4Å; F296-L340 HydrophobicContact CZ-CD1 4.04Å; V336-L340 HydrophobicContact CG1-CD1 4.05Å; V336-L340 HydrophobicContact CG1-CG 4.32Å; V336-L340 VanDerWaalsContact O-CG 3.3Å; V336-L340 WeakPolarHBondContact O-CG 3.38Å; V336-L340 PolarHBondContact O-N 3.13Å; S337-L340 PolarHBondContact O-N 3.31Å; L340-W342 VanDerWaalsContact C-N 3.34Å; L340-W342 PolarHBondContact O-N 3.48Å; L340-F344 HydrophobicContact CD2-CD2 3.78Å; L340-F344 HydrophobicContact CD2-CE2 4.06Å; L340-F344 WeakPolarHBondContact O-CA 3.31Å; L340-F344 VanDerWaalsContact O-CB 3.29Å; L340-F344 WeakPolarHBondContact O-CB 3.5Å; L340-F344 PolarHBondContact O-N 3.36Å
341	V	97.4	Very high	95.9	Very high	3 Å²	3	64.1 Å²	64.1	2%	0.018	32%	0.315	C	S	.	.	H	α-helix	trans	-62.8	-41.5	174.5	170.8	0	0	0	0	111.2	F296 S337 L338 T345 R374 F375 V378 Y381	F296-V341 HydrophobicContact CD2-CG2 4.01Å; F296-V341 HydrophobicContact CE2-CG2 3.94Å; S337-V341 WeakPolarHBondContact O-CB 3.47Å; S337-V341 VanDerWaalsContact O-CG2 3.32Å; S337-V341 WeakPolarHBondContact O-CG2 3.33Å; S337-V341 PolarHBondContact O-N 2.94Å; L338-V341 PolarHBondContact O-N 2.89Å; V341-T345 WeakPolarHBondContact O-CB 3.18Å; V341-T345 PolarHBondContact O-OG1 3.23Å; V341-R374 HydrophobicContact CG1-CB 3.85Å; V341-R374 HydrophobicContact CG1-CG 3.86Å; V341-F375 HydrophobicContact CB-CD1 4.36Å; V341-F375 HydrophobicContact CB-CE1 4.33Å; V341-F375 HydrophobicContact CG1-CD1 3.86Å; V341-F375 HydrophobicContact CG1-CE1 3.85Å; V341-V378 HydrophobicContact CG2-CG2 4.08Å; V341-Y381 HydrophobicContact CG2-CE2 4.3Å
342	W	96.8	Very high	95.7	Very high	152 Å²	152	64.5 Å²	64.5	58%	0.576	31%	0.312	S	S	*	.	H	α-helix	trans	-65.5	-49.4	-179.1	173.6	68.8	0	0	0	112.2	L338 F339 L340 F375	L338-W342 VanDerWaalsContact O-CB 3.31Å; L338-W342 WeakPolarHBondContact O-CB 3.29Å; L338-W342 PolarHBondContact O-N 3.42Å; F339-W342 HydrophobicContact CD2-CE3 4.12Å; F339-W342 HydrophobicContact CD2-CZ3 4.37Å; F339-W342 HydrophobicContact CE2-CE3 4.27Å; F339-W342 HydrophobicContact CE2-CZ3 4.15Å; F339-W342 PolarHBondContact O-N 2.79Å; L340-W342 VanDerWaalsContact C-N 3.34Å; L340-W342 PolarHBondContact O-N 3.48Å; W342-F375 HydrophobicContact CB-CE1 3.76Å; W342-F375 HydrophobicContact CB-CZ 4.04Å; W342-F375 HydrophobicContact CG-CZ 4.48Å
343	K	96.9	Very high	95.4	Very high	121 Å²	121	64.1 Å²	64.1	53%	0.526	32%	0.317	S	S	.	.	H	α-helix	trans	-87.2	-31.3	-170.1	-175.1	60.4	178.2	-179.6	0	113.8	F339	F339-K343 HydrophobicContact CE2-CB 4.39Å; F339-K343 HydrophobicContact CZ-CB 4.39Å; F339-K343 HydrophobicContact CZ-CG 4.46Å; F339-K343 WeakPolarHBondContact O-CB 3.38Å; F339-K343 PolarHBondContact O-N 3.17Å
344	F	96.9	Very high	95.1	Very high	42 Å²	42	62.4 Å²	62.4	18%	0.184	31%	0.308	C	S	.	.	H	α-helix	trans	-121.5	14.5	-165.6	-65.1	-74.4	0	0	0	114.1	F290 H291 F292 P293 F339 L340 Y346	F290-F344 HydrophobicContact CB-CD1 3.91Å; F290-F344 HydrophobicContact CB-CE1 3.95Å; F290-F344 VanDerWaalsContact O-CB 3.28Å; F290-F344 WeakPolarHBondContact O-CB 3.18Å; F290-F344 WeakPolarHBondContact O-CD1 3.26Å; F290-F344 WeakPolarHBondContact O-CG 3.44Å; H291-F344 PolarHBondContact CD2-O 2.89Å; F292-F344 HydrophobicContact CB-CB 4.35Å; F292-F344 HydrophobicContact CD2-CB 3.91Å; F292-F344 AromaticContact CD2-CD1 3.96Å; F292-F344 HydrophobicContact CD2-CD1 3.96Å; F292-F344 AromaticContact CD2-CD2 3.73Å; F292-F344 HydrophobicContact CD2-CD2 3.73Å; F292-F344 HydrophobicContact CD2-CE1 4.38Å; F292-F344 HydrophobicContact CD2-CE2 4.18Å; F292-F344 AromaticContact CD2-CG 3.6Å; F292-F344 HydrophobicContact CD2-CG 3.6Å; F292-F344 HydrophobicContact CD2-CZ 4.48Å; F292-F344 HydrophobicContact CE2-CD1 4.18Å; F292-F344 HydrophobicContact CE2-CD2 4.17Å; F292-F344 HydrophobicContact CE2-CE1 4.15Å; F292-F344 HydrophobicContact CE2-CE2 4.15Å; F292-F344 HydrophobicContact CE2-CG 4.18Å; F292-F344 HydrophobicContact CE2-CZ 4.14Å; P293-F344 WeakPolarHBondContact CD-O 3.32Å; F339-F344 HydrophobicContact CE1-CE2 4.03Å; L340-F344 HydrophobicContact CD2-CD2 3.78Å; L340-F344 HydrophobicContact CD2-CE2 4.06Å; L340-F344 WeakPolarHBondContact O-CA 3.31Å; L340-F344 VanDerWaalsContact O-CB 3.29Å; L340-F344 WeakPolarHBondContact O-CB 3.5Å; L340-F344 PolarHBondContact O-N 3.36Å; F344-Y346 HydrophobicContact CB-CE2 4.46Å; F344-Y346 HydrophobicContact CD1-CE2 4.42Å; F344-Y346 WeakPolarHBondContact O-CD2 3.02Å; F344-Y346 PolarHBondContact O-N 3.44Å
345	T	95.1	Very high	94.8	Very high	23 Å²	23	61.9 Å²	61.9	14%	0.141	30%	0.304	C	S	.	.			trans	-77.7	114.6	167.6	-60.7	0	0	0	0	109.3	V341 W363	V341-T345 WeakPolarHBondContact O-CB 3.18Å; V341-T345 PolarHBondContact O-OG1 3.23Å; T345-W363 HydrophobicContact CG2-CH2 3.75Å; T345-W363 HydrophobicContact CG2-CZ2 4.35Å
346	Y	93.7	Very high	94.7	Very high	79 Å²	79	58.3 Å²	58.3	31%	0.31	28%	0.283	S	S	.	.			trans	-102.8	147.4	175	-67.4	-94.2	0	0	0	110.5	C289 H291 F344 E415	C289-Y346 HydrophobicContact CB-CD1 4.49Å; C289-Y346 HydrophobicContact CB-CD2 4.44Å; C289-Y346 HydrophobicContact CB-CE1 4.27Å; C289-Y346 HydrophobicContact CB-CE2 4.23Å; H291-Y346 HydrophobicContact CB-CD2 3.77Å; H291-Y346 HydrophobicContact CB-CE2 4.47Å; H291-Y346 PolarHBondContact CE1-O 2.88Å; H291-Y346 AromaticContact CG-CD2 3.87Å; H291-Y346 PolarHBondContact NE2-N 3.05Å; F344-Y346 HydrophobicContact CB-CE2 4.46Å; F344-Y346 HydrophobicContact CD1-CE2 4.42Å; F344-Y346 WeakPolarHBondContact O-CD2 3.02Å; F344-Y346 PolarHBondContact O-N 3.44Å; Y346-E415 HydrophobicContact CD1-CG 4.48Å; Y346-E415 HydrophobicContact CG-CG 4.37Å
347	V	92.6	Very high	94.5	Very high	58 Å²	58	56.4 Å²	56.4	35%	0.352	27%	0.269	S	S	.	.			trans	-129.7	99	-179.3	-167.8	0	0	0	0	108.5	L352 W363	V347-L352 HydrophobicContact CG1-CD1 3.77Å; V347-L352 HydrophobicContact CG1-CD2 3.7Å; V347-L352 HydrophobicContact CG1-CG 3.74Å; V347-W363 HydrophobicContact CB-CZ2 4.23Å; V347-W363 HydrophobicContact CG1-CZ2 3.99Å; V347-W363 HydrophobicContact CG2-CH2 4.09Å; V347-W363 HydrophobicContact CG2-CZ2 3.31Å
348	H	92.3	Very high	94.4	Very high	8 Å²	8	57.6 Å²	57.6	4%	0.037	27%	0.274	C	S	.	.			trans	-70.3	144	-177	-166.6	-96.1	0	0	0	111.8	S285 Y350 L351 E415 L416	S285-H348 PolarHBondContact O-NE2 3.31Å; H348-Y350 VanDerWaalsContact C-N 3.27Å; H348-Y350 AromaticContact CE1-CD2 3.22Å; H348-Y350 WeakPolarHBondContact CE1-CD2 3.49Å; H348-Y350 AromaticContact CE1-CE2 3.58Å; H348-Y350 AromaticContact CE1-CG 3.46Å; H348-Y350 VanDerWaalsContact CE1-CG 3.46Å; H348-Y350 WeakPolarHBondContact ND1-CB 3.47Å; H348-Y350 AromaticContact ND1-CD2 3.57Å; H348-Y350 AromaticContact ND1-CG 3.52Å; H348-Y350 PolarHBondContact ND1-N 3.35Å; H348-Y350 VanDerWaalsContact ND1-N 3.18Å; H348-Y350 PolarHBondContact O-N 2.93Å; H348-L351 WeakPolarHBondContact O-CB 3.49Å; H348-L351 PolarHBondContact O-N 3.48Å; H348-E415 HydrophobicContact CB-CG 4.38Å; H348-E415 IonicContact CD2-OE1 3.9Å; H348-E415 IonicContact CD2-OE2 2.95Å; H348-L416 HydrophobicContact CB-CB 4.11Å; H348-L416 HydrophobicContact CB-CD1 3.85Å
349	K	92.4	Very high	94.2	Very high	112 Å²	112	54.7 Å²	54.7	49%	0.487	26%	0.259	S	S	.	.	H	α-helix	trans	-54.4	-39.3	179.3	59.4	-178.1	176.7	178.9	0	113.3	S285 L351 L352 A353	S285-K349 PolarHBondContact OG-NZ 3.16Å; K349-L351 VanDerWaalsContact C-N 3.32Å; K349-L351 PolarHBondContact O-N 3.16Å; K349-L352 PolarHBondContact O-N 2.85Å; K349-L352 VanDerWaalsContact O-N 3.16Å; K349-A353 WeakPolarHBondContact O-CB 3.41Å; K349-A353 PolarHBondContact O-N 3.22Å
350	Y	90.6	Very high	94.1	Very high	93 Å²	93	50.9 Å²	50.9	37%	0.365	24%	0.242	S	C	.	.	H	α-helix	trans	-65.7	-33.8	179.6	-58.9	-24.5	0	0	0	112.5	D282 S285 H348 L352 A353 D354	D282-Y350 PolarHBondContact OD2-OH 3.06Å; S285-Y350 WeakPolarHBondContact CB-OH 3.36Å; S285-Y350 PolarHBondContact OG-OH 2.84Å; H348-Y350 VanDerWaalsContact C-N 3.27Å; H348-Y350 AromaticContact CE1-CD2 3.22Å; H348-Y350 WeakPolarHBondContact CE1-CD2 3.49Å; H348-Y350 AromaticContact CE1-CE2 3.58Å; H348-Y350 AromaticContact CE1-CG 3.46Å; H348-Y350 VanDerWaalsContact CE1-CG 3.46Å; H348-Y350 WeakPolarHBondContact ND1-CB 3.47Å; H348-Y350 AromaticContact ND1-CD2 3.57Å; H348-Y350 AromaticContact ND1-CG 3.52Å; H348-Y350 PolarHBondContact ND1-N 3.35Å; H348-Y350 VanDerWaalsContact ND1-N 3.18Å; H348-Y350 PolarHBondContact O-N 2.93Å; Y350-L352 PolarHBondContact O-N 3.42Å; Y350-A353 PolarHBondContact O-N 3.02Å; Y350-D354 WeakPolarHBondContact O-CB 3.38Å; Y350-D354 PolarHBondContact O-N 3.47Å; Y350-D354 VanDerWaalsContact O-N 3.11Å
351	L	92.6	Very high	94	Very high	10 Å²	10	52.6 Å²	52.6	5%	0.052	25%	0.247	C	C	.	.	H	α-helix	trans	-65	-28.6	176.1	-176.7	62.7	0	0	0	112.4	H348 K349 P359 F360 W363 L416 L417	H348-L351 WeakPolarHBondContact O-CB 3.49Å; H348-L351 PolarHBondContact O-N 3.48Å; K349-L351 VanDerWaalsContact C-N 3.32Å; K349-L351 PolarHBondContact O-N 3.16Å; L351-P359 HydrophobicContact CD1-CB 3.81Å; L351-F360 WeakPolarHBondContact O-CD2 3.37Å; L351-W363 HydrophobicContact CD1-CB 4.28Å; L351-W363 HydrophobicContact CD2-CB 4.02Å; L351-W363 HydrophobicContact CD2-CD2 3.6Å; L351-W363 HydrophobicContact CD2-CE3 3.8Å; L351-W363 HydrophobicContact CD2-CG 3.67Å; L351-W363 HydrophobicContact CG-CB 4.1Å; L351-W363 HydrophobicContact CG-CG 4.11Å; L351-L416 HydrophobicContact CB-CD1 3.85Å; L351-L417 HydrophobicContact CD2-CB 4.17Å
352	L	91.9	Very high	93.9	Very high	77 Å²	77	55.1 Å²	55.1	40%	0.403	26%	0.26	S	S	.	.	H	α-helix	trans	-93.6	-22.7	-178.7	-60.5	-175.5	0	0	0	113.4	V347 K349 Y350 F360	V347-L352 HydrophobicContact CG1-CD1 3.77Å; V347-L352 HydrophobicContact CG1-CD2 3.7Å; V347-L352 HydrophobicContact CG1-CG 3.74Å; K349-L352 PolarHBondContact O-N 2.85Å; K349-L352 VanDerWaalsContact O-N 3.16Å; Y350-L352 PolarHBondContact O-N 3.42Å; L352-F360 WeakPolarHBondContact O-CE2 3.23Å
353	A	89.7	Confident	93.8	Very high	75 Å²	75	48.5 Å²	48.5	62%	0.62	24%	0.235	S	C	*	.	H	α-helix	trans	-93.1	-30.4	-175.9	0	0	0	0	0	112.8	K349 Y350	K349-A353 WeakPolarHBondContact O-CB 3.41Å; K349-A353 PolarHBondContact O-N 3.22Å; Y350-A353 PolarHBondContact O-N 3.02Å
354	D	90.6	Very high	93.7	Very high	22 Å²	22	47.7 Å²	47.7	12%	0.118	23%	0.231	C	C	.	.			trans	-104.9	94.9	-167.9	-163.1	-22.2	0	0	0	113.2	M39 Y350 R356 H357 F360	M39-D354 VanDerWaalsContact CE-OD2 3.32Å; M39-D354 WeakPolarHBondContact CE-OD2 3.42Å; Y350-D354 WeakPolarHBondContact O-CB 3.38Å; Y350-D354 PolarHBondContact O-N 3.47Å; Y350-D354 VanDerWaalsContact O-N 3.11Å; D354-R356 PolarHBondContact O-N 3.42Å; D354-R356 WeakPolarHBondContact OD1-CB 3.41Å; D354-R356 WeakPolarHBondContact OD1-CG 3.1Å; D354-R356 IonicContact OD1-CZ 2.7Å; D354-R356 PolarHBondContact OD1-N 3.48Å; D354-R356 IonicContact OD1-NE 3Å; D354-R356 PolarHBondContact OD1-NE 3.33Å; D354-R356 IonicContact OD1-NH2 3.3Å; D354-R356 IonicContact OD2-CZ 3.59Å; D354-R356 IonicContact OD2-NE 2.76Å; D354-R356 PolarHBondContact OD2-NE 3.48Å; D354-R356 IonicContact OD2-NH2 3.6Å; D354-R356 PolarHBondContact OD2-NH2 2.89Å; D354-H357 VanDerWaalsContact CG-ND1 3.28Å; D354-H357 IonicContact OD1-ND1 3.41Å; D354-H357 IonicContact OD2-CE1 3.68Å; D354-H357 PolarHBondContact OD2-CE1 2.95Å; D354-H357 IonicContact OD2-ND1 3.71Å; D354-H357 PolarHBondContact OD2-ND1 3.5Å; D354-F360 VanDerWaalsContact O-CB 3.26Å; D354-F360 WeakPolarHBondContact O-CB 3.47Å; D354-F360 WeakPolarHBondContact O-CD2 3.31Å; D354-F360 WeakPolarHBondContact O-CG 3.4Å
355	N	93.1	Very high	93.6	Very high	37 Å²	37	50 Å²	50	20%	0.198	25%	0.246	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.1	6.7	177.9	76.3	-15.1	0	0	0	114.5	F360 Y361 F464 W466	N355-F360 HydrophobicContact CB-CD1 3.88Å; N355-F360 HydrophobicContact CB-CD2 4.36Å; N355-F360 HydrophobicContact CB-CE1 3.58Å; N355-F360 HydrophobicContact CB-CE2 4.09Å; N355-F360 HydrophobicContact CB-CG 4.3Å; N355-F360 HydrophobicContact CB-CZ 3.71Å; N355-Y361 WeakPolarHBondContact O-CE2 3.17Å; N355-Y361 PolarHBondContact O-OH 3.31Å; N355-F464 WeakPolarHBondContact OD1-CE2 3.14Å; N355-F464 VanDerWaalsContact OD1-CZ 3.31Å; N355-F464 WeakPolarHBondContact OD1-CZ 3.32Å; N355-W466 WeakPolarHBondContact OD1-CZ2 3.26Å; N355-W466 PolarHBondContact OD1-NE1 2.89Å
356	R	94.3	Very high	93.6	Very high	42 Å²	42	52.7 Å²	52.7	16%	0.158	26%	0.258	C	S	.	.	T	Hydrogen-bonded Turn	trans	-79.1	-27	175.1	-61.5	167.3	-64.1	179.9	7.5	111.6	Y38 M39 D354 F464 W466 Q473 F475 M476	Y38-R356 WeakPolarHBondContact OH-CD 3.24Å; M39-R356 HydrophobicContact CE-CB 4.39Å; M39-R356 VanDerWaalsContact CE-NH2 3.25Å; M39-R356 HydrophobicContact SD-CB 4.36Å; M39-R356 WeakPolarHBondContact SD-CD 3.33Å; M39-R356 HydrophobicContact SD-CG 4.49Å; M39-R356 PolarHBondContact SD-NE 2.96Å; M39-R356 PolarHBondContact SD-NH1 2.98Å; M39-R356 PolarHBondContact SD-NH2 3.46Å; M39-R356 VanDerWaalsContact SD-NH2 3.4Å; D354-R356 PolarHBondContact O-N 3.42Å; D354-R356 WeakPolarHBondContact OD1-CB 3.41Å; D354-R356 WeakPolarHBondContact OD1-CG 3.1Å; D354-R356 IonicContact OD1-CZ 2.7Å; D354-R356 PolarHBondContact OD1-N 3.48Å; D354-R356 IonicContact OD1-NE 3Å; D354-R356 PolarHBondContact OD1-NE 3.33Å; D354-R356 IonicContact OD1-NH2 3.3Å; D354-R356 IonicContact OD2-CZ 3.59Å; D354-R356 IonicContact OD2-NE 2.76Å; D354-R356 PolarHBondContact OD2-NE 3.48Å; D354-R356 IonicContact OD2-NH2 3.6Å; D354-R356 PolarHBondContact OD2-NH2 2.89Å; R356-F464 HydrophobicContact CG-CE1 4.47Å; R356-F464 HydrophobicContact CG-CE2 4.4Å; R356-F464 HydrophobicContact CG-CZ 3.64Å; R356-W466 HydrophobicContact CG-CH2 4.41Å; R356-W466 HydrophobicContact CG-CZ2 4.17Å; R356-Q473 HydrophobicContact CG-CB 4.19Å; R356-F475 CarbonylContact O-C 3.56Å; R356-F475 VanDerWaalsContact O-CA 3.3Å; R356-F475 WeakPolarHBondContact O-CA 3.05Å; R356-M476 PolarHBondContact O-N 3.23Å
357	H	95.2	Very high	93.6	Very high	29 Å²	29	50.4 Å²	50.4	13%	0.134	25%	0.249	C	C	.	.	B	Isolated β-bridge	trans	-90.7	140.8	-173.1	-64.7	88.1	0	0	0	112.8	M39 D354 F360 M476 W477	M39-H357 WeakPolarHBondContact CE-CE1 3.32Å; D354-H357 VanDerWaalsContact CG-ND1 3.28Å; D354-H357 IonicContact OD1-ND1 3.41Å; D354-H357 IonicContact OD2-CE1 3.68Å; D354-H357 PolarHBondContact OD2-CE1 2.95Å; D354-H357 IonicContact OD2-ND1 3.71Å; D354-H357 PolarHBondContact OD2-ND1 3.5Å; H357-F360 VanDerWaalsContact O-CB 3.27Å; H357-F360 WeakPolarHBondContact O-CB 3.3Å; H357-F360 PolarHBondContact O-N 3.23Å; H357-M476 CarbonylContact C-O 3.48Å; H357-M476 VanDerWaalsContact CA-O 3.31Å; H357-M476 WeakPolarHBondContact CA-O 3.22Å; H357-W477 PolarHBondContact CD2-O 3.26Å
358	F	95	Very high	93.6	Very high	28 Å²	28	52.6 Å²	52.6	12%	0.123	26%	0.256	C	S	.	.	H	α-helix	trans	-61.8	-38.4	176.2	-56.6	-49.2	0	0	0	114.3	F360 Y361 I362 T455 L458 F475 M476 W477	F358-F360 PolarHBondContact O-N 3.01Å; F358-Y361 PolarHBondContact O-N 3.4Å; F358-I362 PolarHBondContact O-N 3.42Å; F358-T455 HydrophobicContact CD2-CG2 4.21Å; F358-T455 HydrophobicContact CE2-CG2 3.42Å; F358-T455 VanDerWaalsContact CE2-CG2 3.42Å; F358-T455 HydrophobicContact CZ-CG2 3.84Å; F358-L458 HydrophobicContact CE1-CD1 3.79Å; F358-L458 HydrophobicContact CZ-CD1 4.13Å; F358-F475 HydrophobicContact CE1-CB 3.83Å; F358-F475 HydrophobicContact CZ-CB 4.28Å; F358-M476 WeakPolarHBondContact CD2-O 3.31Å; F358-M476 WeakPolarHBondContact CE2-O 3.4Å; F358-M476 WeakPolarHBondContact CG-O 3.39Å; F358-M476 PolarHBondContact N-O 2.99Å; F358-W477 HydrophobicContact CB-CE3 4.41Å; F358-W477 HydrophobicContact CD2-CB 4.42Å; F358-W477 AromaticContact CD2-CD2 3.68Å; F358-W477 HydrophobicContact CD2-CD2 3.68Å; F358-W477 AromaticContact CD2-CE3 3.59Å; F358-W477 HydrophobicContact CD2-CE3 3.59Å; F358-W477 HydrophobicContact CD2-CG 4.04Å; F358-W477 HydrophobicContact CD2-CZ3 4.03Å; F358-W477 HydrophobicContact CE2-CD2 4.06Å; F358-W477 HydrophobicContact CE2-CE3 4.41Å; F358-W477 HydrophobicContact CE2-CG 4.16Å; F358-W477 HydrophobicContact CG-CE3 4.49Å
359	P	95.4	Very high	93.7	Very high	2 Å²	2	62.1 Å²	62.1	1%	0.013	29%	0.291	C	S	.	.	H	α-helix	trans	-52.3	-33.7	172.1	-31	36.4	0	0	0	114.6	L351 Y361 I362 W363 F419 W477	L351-P359 HydrophobicContact CD1-CB 3.81Å; P359-Y361 VanDerWaalsContact C-N 3.31Å; P359-Y361 PolarHBondContact O-N 2.96Å; P359-I362 PolarHBondContact O-N 3.07Å; P359-W363 WeakPolarHBondContact O-CB 3.5Å; P359-W363 PolarHBondContact O-N 2.96Å; P359-F419 HydrophobicContact CG-CD2 4.07Å; P359-F419 HydrophobicContact CG-CE2 4.2Å; P359-F419 HydrophobicContact CG-CG 4.31Å; P359-W477 WeakPolarHBondContact CD-OXT 3.49Å
360	F	95.9	Very high	93.8	Very high	26 Å²	26	62 Å²	62	11%	0.114	29%	0.292	C	S	.	.	H	α-helix	trans	-56.4	-46	174.8	168.7	-84.1	0	0	0	111.2	L351 L352 D354 N355 H357 F358 W363 K364	L351-F360 WeakPolarHBondContact O-CD2 3.37Å; L352-F360 WeakPolarHBondContact O-CE2 3.23Å; D354-F360 VanDerWaalsContact O-CB 3.26Å; D354-F360 WeakPolarHBondContact O-CB 3.47Å; D354-F360 WeakPolarHBondContact O-CD2 3.31Å; D354-F360 WeakPolarHBondContact O-CG 3.4Å; N355-F360 HydrophobicContact CB-CD1 3.88Å; N355-F360 HydrophobicContact CB-CD2 4.36Å; N355-F360 HydrophobicContact CB-CE1 3.58Å; N355-F360 HydrophobicContact CB-CE2 4.09Å; N355-F360 HydrophobicContact CB-CG 4.3Å; N355-F360 HydrophobicContact CB-CZ 3.71Å; H357-F360 VanDerWaalsContact O-CB 3.27Å; H357-F360 WeakPolarHBondContact O-CB 3.3Å; H357-F360 PolarHBondContact O-N 3.23Å; F358-F360 PolarHBondContact O-N 3.01Å; F360-W363 PolarHBondContact O-N 2.85Å; F360-K364 HydrophobicContact CE1-CB 4.39Å; F360-K364 HydrophobicContact CE1-CD 3.66Å; F360-K364 HydrophobicContact CZ-CD 3.87Å; F360-K364 VanDerWaalsContact O-CB 3.23Å; F360-K364 WeakPolarHBondContact O-CB 3.23Å; F360-K364 PolarHBondContact O-N 3.5Å
361	Y	95.5	Very high	93.8	Very high	66 Å²	66	66.4 Å²	66.4	26%	0.259	31%	0.313	S	S	.	.	H	α-helix	trans	-73.2	-33.9	-177.7	-69.8	-76.2	0	0	0	112.8	N355 F358 P359 W363 N365 F475	N355-Y361 WeakPolarHBondContact O-CE2 3.17Å; N355-Y361 PolarHBondContact O-OH 3.31Å; F358-Y361 PolarHBondContact O-N 3.4Å; P359-Y361 VanDerWaalsContact C-N 3.31Å; P359-Y361 PolarHBondContact O-N 2.96Å; Y361-W363 VanDerWaalsContact C-N 3.32Å; Y361-N365 WeakPolarHBondContact O-CB 3.26Å; Y361-N365 PolarHBondContact O-N 3.07Å; Y361-N365 PolarHBondContact O-ND2 3.16Å; Y361-F475 AromaticContact CE2-CD1 3.97Å; Y361-F475 HydrophobicContact CE2-CD1 3.97Å; Y361-F475 AromaticContact CE2-CE1 3.76Å; Y361-F475 HydrophobicContact CE2-CE1 3.76Å; Y361-F475 AromaticContact CZ-CE1 3.83Å; Y361-F475 WeakPolarHBondContact OH-CE1 3.36Å
362	I	94.8	Very high	93.9	Very high	55 Å²	55	70.5 Å²	70.5	28%	0.282	34%	0.335	S	S	.	.	H	α-helix	trans	-63.1	-45.4	172.3	-69.2	169.7	0	0	0	109.3	F358 P359 I366 Y367 F419	F358-I362 PolarHBondContact O-N 3.42Å; P359-I362 PolarHBondContact O-N 3.07Å; I362-I366 HydrophobicContact CG2-CD1 4.39Å; I362-I366 VanDerWaalsContact O-CB 3.24Å; I362-I366 WeakPolarHBondContact O-CB 3.48Å; I362-I366 PolarHBondContact O-N 3.49Å; I362-I366 VanDerWaalsContact O-N 3.09Å; I362-Y367 HydrophobicContact CG2-CD2 4.32Å; I362-Y367 HydrophobicContact CG2-CE2 4.05Å; I362-Y367 PolarHBondContact O-N 3.11Å; I362-F419 HydrophobicContact CD1-CE2 3.57Å; I362-F419 HydrophobicContact CD1-CZ 3.46Å; I362-F419 VanDerWaalsContact CD1-CZ 3.46Å
363	W	95.4	Very high	94	Very high	13 Å²	13	68.1 Å²	68.1	5%	0.049	32%	0.323	C	S	.	.	H	α-helix	trans	-63.9	-52.3	177.8	-161.9	-97.2	0	0	0	112	Y297 T345 V347 L351 P359 F360 Y361 Y367 Q368 L417	Y297-W363 HydrophobicContact CE2-CZ3 4.47Å; T345-W363 HydrophobicContact CG2-CH2 3.75Å; T345-W363 HydrophobicContact CG2-CZ2 4.35Å; V347-W363 HydrophobicContact CB-CZ2 4.23Å; V347-W363 HydrophobicContact CG1-CZ2 3.99Å; V347-W363 HydrophobicContact CG2-CH2 4.09Å; V347-W363 HydrophobicContact CG2-CZ2 3.31Å; L351-W363 HydrophobicContact CD1-CB 4.28Å; L351-W363 HydrophobicContact CD2-CB 4.02Å; L351-W363 HydrophobicContact CD2-CD2 3.6Å; L351-W363 HydrophobicContact CD2-CE3 3.8Å; L351-W363 HydrophobicContact CD2-CG 3.67Å; L351-W363 HydrophobicContact CG-CB 4.1Å; L351-W363 HydrophobicContact CG-CG 4.11Å; P359-W363 WeakPolarHBondContact O-CB 3.5Å; P359-W363 PolarHBondContact O-N 2.96Å; F360-W363 PolarHBondContact O-N 2.85Å; Y361-W363 VanDerWaalsContact C-N 3.32Å; W363-Y367 HydrophobicContact CD2-CD2 4.46Å; W363-Y367 HydrophobicContact CD2-CG 4.28Å; W363-Y367 HydrophobicContact CE3-CD1 4.43Å; W363-Y367 AromaticContact CE3-CD2 3.86Å; W363-Y367 HydrophobicContact CE3-CD2 3.86Å; W363-Y367 HydrophobicContact CE3-CE2 4.4Å; W363-Y367 AromaticContact CE3-CG 3.87Å; W363-Y367 HydrophobicContact CE3-CG 3.87Å; W363-Y367 HydrophobicContact CH2-CD1 4.27Å; W363-Y367 HydrophobicContact CH2-CG 4.39Å; W363-Y367 HydrophobicContact CZ3-CD1 4.05Å; W363-Y367 HydrophobicContact CZ3-CD2 4.22Å; W363-Y367 HydrophobicContact CZ3-CE1 4.38Å; W363-Y367 AromaticContact CZ3-CG 3.96Å; W363-Y367 HydrophobicContact CZ3-CG 3.96Å; W363-Y367 CarbonylContact O-C 3.41Å; W363-Y367 WeakPolarHBondContact O-CA 3.43Å; W363-Y367 WeakPolarHBondContact O-CB 3.17Å; W363-Y367 PolarHBondContact O-N 3.2Å; W363-Q368 PolarHBondContact O-N 3.19Å; W363-L417 HydrophobicContact CE3-CD2 4Å; W363-L417 HydrophobicContact CZ3-CD2 4.17Å
364	K	95.3	Very high	94.2	Very high	104 Å²	104	68.2 Å²	68.2	45%	0.452	31%	0.307	S	S	.	.	H	α-helix	trans	-62.2	-50.4	-178.8	-177.8	-177.4	175.8	-179.4	0	112.8	F360	F360-K364 HydrophobicContact CE1-CB 4.39Å; F360-K364 HydrophobicContact CE1-CD 3.66Å; F360-K364 HydrophobicContact CZ-CD 3.87Å; F360-K364 VanDerWaalsContact O-CB 3.23Å; F360-K364 WeakPolarHBondContact O-CB 3.23Å; F360-K364 PolarHBondContact O-N 3.5Å
365	N	95.1	Very high	94.4	Very high	92 Å²	92	69.3 Å²	69.3	49%	0.492	31%	0.311	S	S	.	.	H	α-helix	trans	-86.8	-21.8	-169	-60.7	-21.5	0	0	0	113.3	Y361	Y361-N365 WeakPolarHBondContact O-CB 3.26Å; Y361-N365 PolarHBondContact O-N 3.07Å; Y361-N365 PolarHBondContact O-ND2 3.16Å
366	I	94.1	Very high	94.6	Very high	79 Å²	79	73.7 Å²	73.7	41%	0.405	33%	0.334	S	S	.	.	T	Hydrogen-bonded Turn	trans	-108.5	-66.1	179.6	-52.7	179.7	0	0	0	110.1	I362 Q368 R369 V373	I362-I366 HydrophobicContact CG2-CD1 4.39Å; I362-I366 VanDerWaalsContact O-CB 3.24Å; I362-I366 WeakPolarHBondContact O-CB 3.48Å; I362-I366 PolarHBondContact O-N 3.49Å; I362-I366 VanDerWaalsContact O-N 3.09Å; I366-Q368 PolarHBondContact O-N 3.38Å; I366-R369 WeakPolarHBondContact O-CB 3.44Å; I366-R369 PolarHBondContact O-N 2.89Å; I366-V373 HydrophobicContact CG2-CG1 4.09Å; I366-V373 WeakPolarHBondContact O-CG1 3.47Å
367	Y	93.2	Very high	94.7	Very high	31 Å²	31	73.7 Å²	73.7	12%	0.122	34%	0.337	C	S	.	.	G	3₁₀ helix	trans	-68.1	-40	-171.5	-73.1	-92.5	0	0	0	113.3	Y297 I362 W363 R369 R374 L377 Y381	Y297-Y367 WeakPolarHBondContact CD1-OH 3.2Å; Y297-Y367 AromaticContact CE1-CE1 3.84Å; Y297-Y367 HydrophobicContact CE1-CE1 3.84Å; Y297-Y367 AromaticContact CE1-CZ 3.74Å; Y297-Y367 WeakPolarHBondContact CE1-OH 3.24Å; I362-Y367 HydrophobicContact CG2-CD2 4.32Å; I362-Y367 HydrophobicContact CG2-CE2 4.05Å; I362-Y367 PolarHBondContact O-N 3.11Å; W363-Y367 HydrophobicContact CD2-CD2 4.46Å; W363-Y367 HydrophobicContact CD2-CG 4.28Å; W363-Y367 HydrophobicContact CE3-CD1 4.43Å; W363-Y367 AromaticContact CE3-CD2 3.86Å; W363-Y367 HydrophobicContact CE3-CD2 3.86Å; W363-Y367 HydrophobicContact CE3-CE2 4.4Å; W363-Y367 AromaticContact CE3-CG 3.87Å; W363-Y367 HydrophobicContact CE3-CG 3.87Å; W363-Y367 HydrophobicContact CH2-CD1 4.27Å; W363-Y367 HydrophobicContact CH2-CG 4.39Å; W363-Y367 HydrophobicContact CZ3-CD1 4.05Å; W363-Y367 HydrophobicContact CZ3-CD2 4.22Å; W363-Y367 HydrophobicContact CZ3-CE1 4.38Å; W363-Y367 AromaticContact CZ3-CG 3.96Å; W363-Y367 HydrophobicContact CZ3-CG 3.96Å; W363-Y367 CarbonylContact O-C 3.41Å; W363-Y367 WeakPolarHBondContact O-CA 3.43Å; W363-Y367 WeakPolarHBondContact O-CB 3.17Å; W363-Y367 PolarHBondContact O-N 3.2Å; Y367-R369 VanDerWaalsContact C-N 3.33Å; Y367-R374 HydrophobicContact CD1-CB 4.34Å; Y367-L377 HydrophobicContact CD1-CD1 4.19Å; Y367-L377 HydrophobicContact CE1-CD1 3.55Å; Y367-L377 HydrophobicContact CE2-CD1 4.36Å; Y367-Y381 VanDerWaalsContact CE1-OH 3.29Å; Y367-Y381 WeakPolarHBondContact CE1-OH 3.46Å; Y367-Y381 PolarHBondContact OH-OH 3.16Å
368	Q	93.6	Very high	94.8	Very high	104 Å²	104	72.4 Å²	72.4	49%	0.486	33%	0.331	S	S	.	.	G	3₁₀ helix	trans	-83.7	-4.9	179.9	-68.9	-174.7	-36.9	0	0	113.9	W363 I366 H370	W363-Q368 PolarHBondContact O-N 3.19Å; I366-Q368 PolarHBondContact O-N 3.38Å; Q368-H370 VanDerWaalsContact C-N 3.27Å; Q368-H370 PolarHBondContact O-N 3.31Å
369	R	93.4	Very high	94.9	Very high	207 Å²	207	75.1 Å²	75.1	78%	0.781	35%	0.351	S	S	*	.	G	3₁₀ helix	trans	-59.9	-38.8	-179.8	-172.4	176.1	-179.4	119.3	0.5	112.2	I366 Y367	I366-R369 WeakPolarHBondContact O-CB 3.44Å; I366-R369 PolarHBondContact O-N 2.89Å; Y367-R369 VanDerWaalsContact C-N 3.33Å
370	H	94.3	Very high	95	Very high	110 Å²	110	77.1 Å²	77.1	51%	0.509	37%	0.368	S	S	.	.			trans	-156.5	146.3	172.8	-171	-98.7	0	0	0	110.6	Q368 L372 V373	Q368-H370 VanDerWaalsContact C-N 3.27Å; Q368-H370 PolarHBondContact O-N 3.31Å; H370-L372 WeakPolarHBondContact ND1-CB 3.26Å; H370-L372 PolarHBondContact ND1-N 2.72Å; H370-L372 PolarHBondContact O-N 3.26Å; H370-V373 HydrophobicContact CB-CG2 4.02Å; H370-V373 WeakPolarHBondContact O-CB 3.17Å; H370-V373 WeakPolarHBondContact O-CG2 3.47Å; H370-V373 PolarHBondContact O-N 3.33Å
371	K	90.8	Very high	95	Very high	185 Å²	185	76.2 Å²	76.2	80%	0.804	36%	0.364	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.1	-25.2	-177.2	-65.2	-178.2	-178.5	177.6	0	113.8
372	L	95.1	Very high	95.1	Very high	97 Å²	97	73.8 Å²	73.8	51%	0.508	36%	0.355	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.8	-17.6	179.8	-61.3	178.3	0	0	0	114.4	H370 R374 F375 L376	H370-L372 WeakPolarHBondContact ND1-CB 3.26Å; H370-L372 PolarHBondContact ND1-N 2.72Å; H370-L372 PolarHBondContact O-N 3.26Å; L372-R374 VanDerWaalsContact C-N 3.28Å; L372-R374 PolarHBondContact O-N 3.22Å; L372-F375 HydrophobicContact CD2-CD2 4.3Å; L372-F375 WeakPolarHBondContact O-CB 3.43Å; L372-F375 PolarHBondContact O-N 3.28Å; L372-L376 PolarHBondContact O-N 3.14Å; L372-L376 VanDerWaalsContact O-N 3.07Å
373	V	94.6	Very high	95.2	Very high	26 Å²	26	72.8 Å²	72.8	16%	0.158	35%	0.349	C	S	.	.	H	α-helix	trans	-57.3	-42.5	-173.1	174.1	0	0	0	0	111.6	I366 H370 F375 L376 L377	I366-V373 HydrophobicContact CG2-CG1 4.09Å; I366-V373 WeakPolarHBondContact O-CG1 3.47Å; H370-V373 HydrophobicContact CB-CG2 4.02Å; H370-V373 WeakPolarHBondContact O-CB 3.17Å; H370-V373 WeakPolarHBondContact O-CG2 3.47Å; H370-V373 PolarHBondContact O-N 3.33Å; V373-F375 PolarHBondContact O-N 3.18Å; V373-F375 VanDerWaalsContact O-N 3.11Å; V373-L376 PolarHBondContact O-N 2.84Å; V373-L377 HydrophobicContact CG1-CD1 4.16Å; V373-L377 HydrophobicContact CG1-CG 4.28Å; V373-L377 WeakPolarHBondContact O-CG 3.02Å; V373-L377 PolarHBondContact O-N 3.03Å; V373-L377 VanDerWaalsContact O-N 3.08Å
374	R	93.1	Very high	95.3	Very high	77 Å²	77	72.6 Å²	72.6	29%	0.291	35%	0.349	S	S	.	.	H	α-helix	trans	-54.7	-32.7	177.5	64.5	-179.3	177.5	165.9	1.6	113.5	V341 Y367 L372	V341-R374 HydrophobicContact CG1-CB 3.85Å; V341-R374 HydrophobicContact CG1-CG 3.86Å; Y367-R374 HydrophobicContact CD1-CB 4.34Å; L372-R374 VanDerWaalsContact C-N 3.28Å; L372-R374 PolarHBondContact O-N 3.22Å
375	F	96.6	Very high	95.4	Very high	46 Å²	46	67.9 Å²	67.9	20%	0.202	33%	0.33	C	S	.	.	H	α-helix	trans	-83	-36.9	177.1	-56.4	-63.9	0	0	0	112	L338 V341 W342 L372 V373 L377 V378	L338-F375 HydrophobicContact CD2-CB 3.85Å; L338-F375 HydrophobicContact CD2-CD1 3.81Å; L338-F375 HydrophobicContact CD2-CG 4.24Å; V341-F375 HydrophobicContact CB-CD1 4.36Å; V341-F375 HydrophobicContact CB-CE1 4.33Å; V341-F375 HydrophobicContact CG1-CD1 3.86Å; V341-F375 HydrophobicContact CG1-CE1 3.85Å; W342-F375 HydrophobicContact CB-CE1 3.76Å; W342-F375 HydrophobicContact CB-CZ 4.04Å; W342-F375 HydrophobicContact CG-CZ 4.48Å; L372-F375 HydrophobicContact CD2-CD2 4.3Å; L372-F375 WeakPolarHBondContact O-CB 3.43Å; L372-F375 PolarHBondContact O-N 3.28Å; V373-F375 PolarHBondContact O-N 3.18Å; V373-F375 VanDerWaalsContact O-N 3.11Å; F375-L377 PolarHBondContact O-N 3.08Å; F375-V378 VanDerWaalsContact O-CB 3.32Å; F375-V378 WeakPolarHBondContact O-CB 3.24Å; F375-V378 WeakPolarHBondContact O-CG2 3.2Å; F375-V378 PolarHBondContact O-N 3.41Å
376	L	96.4	Very high	95.4	Very high	128 Å²	128	65.5 Å²	65.5	67%	0.67	31%	0.314	S	S	*	.	H	α-helix	trans	-64.2	-19.7	176.1	-64.4	175.8	0	0	0	113	L372 V373 P379	L372-L376 PolarHBondContact O-N 3.14Å; L372-L376 VanDerWaalsContact O-N 3.07Å; V373-L376 PolarHBondContact O-N 2.84Å; L376-P379 WeakPolarHBondContact O-CD 3.34Å
377	L	96.4	Very high	95.4	Very high	43 Å²	43	61.9 Å²	61.9	23%	0.225	30%	0.296	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80.2	-12.8	174.7	-67.2	174	0	0	0	113.8	Y367 V373 F375 A380 Y381	Y367-L377 HydrophobicContact CD1-CD1 4.19Å; Y367-L377 HydrophobicContact CE1-CD1 3.55Å; Y367-L377 HydrophobicContact CE2-CD1 4.36Å; V373-L377 HydrophobicContact CG1-CD1 4.16Å; V373-L377 HydrophobicContact CG1-CG 4.28Å; V373-L377 WeakPolarHBondContact O-CG 3.02Å; V373-L377 PolarHBondContact O-N 3.03Å; V373-L377 VanDerWaalsContact O-N 3.08Å; F375-L377 PolarHBondContact O-N 3.08Å; L377-A380 WeakPolarHBondContact O-CA 3.3Å; L377-A380 WeakPolarHBondContact O-CB 3.47Å; L377-A380 PolarHBondContact O-N 3.14Å; L377-Y381 HydrophobicContact CB-CD2 4.45Å; L377-Y381 HydrophobicContact CB-CE1 4.13Å; L377-Y381 HydrophobicContact CB-CE2 3.77Å; L377-Y381 WeakPolarHBondContact CD1-OH 3.49Å; L377-Y381 PolarHBondContact O-N 2.76Å
378	V	97.7	Very high	95.4	Very high	1 Å²	1	60.5 Å²	60.5	1%	0.006	29%	0.291	C	S	.	.	H	α-helix	trans	-56.3	-43.4	-178.2	170.2	0	0	0	0	113.7	T334 L338 V341 F375 A380 Y381 I382	T334-V378 HydrophobicContact CG2-CG1 4.13Å; L338-V378 HydrophobicContact CD2-CB 4.37Å; L338-V378 HydrophobicContact CD2-CG2 3.9Å; L338-V378 HydrophobicContact CG-CG1 4.48Å; L338-V378 HydrophobicContact CG-CG2 4.38Å; V341-V378 HydrophobicContact CG2-CG2 4.08Å; F375-V378 VanDerWaalsContact O-CB 3.32Å; F375-V378 WeakPolarHBondContact O-CB 3.24Å; F375-V378 WeakPolarHBondContact O-CG2 3.2Å; F375-V378 PolarHBondContact O-N 3.41Å; V378-A380 VanDerWaalsContact C-N 3.26Å; V378-A380 PolarHBondContact O-N 2.82Å; V378-Y381 HydrophobicContact CG2-CD2 4.26Å; V378-Y381 WeakPolarHBondContact O-CB 3.36Å; V378-Y381 PolarHBondContact O-N 2.73Å; V378-Y381 VanDerWaalsContact O-N 3.15Å; V378-I382 HydrophobicContact CG1-CD1 3.81Å; V378-I382 HydrophobicContact CG1-CG1 4.29Å; V378-I382 WeakPolarHBondContact O-CG1 3.47Å; V378-I382 PolarHBondContact O-N 3.37Å
379	P	97	Very high	95.4	Very high	85 Å²	85	59.4 Å²	59.4	55%	0.552	29%	0.287	S	S	*	.	H	α-helix	trans	-57.3	-38.8	173.9	-25.8	35.6	0	0	0	113.1	L376 F383	L376-P379 WeakPolarHBondContact O-CD 3.34Å; P379-F383 PolarHBondContact O-N 3.17Å
380	A	96.3	Very high	95.3	Very high	44 Å²	44	50.8 Å²	50.8	36%	0.364	26%	0.256	S	S	.	.	H	α-helix	trans	-66.9	-44.2	175.9	0	0	0	0	0	111	L377 V378 I382 F383 T384	L377-A380 WeakPolarHBondContact O-CA 3.3Å; L377-A380 WeakPolarHBondContact O-CB 3.47Å; L377-A380 PolarHBondContact O-N 3.14Å; V378-A380 VanDerWaalsContact C-N 3.26Å; V378-A380 PolarHBondContact O-N 2.82Å; A380-I382 VanDerWaalsContact C-N 3.34Å; A380-I382 PolarHBondContact O-N 3.11Å; A380-F383 PolarHBondContact O-N 2.96Å; A380-T384 WeakPolarHBondContact O-CG2 3.26Å; A380-T384 PolarHBondContact O-N 3.18Å; A380-T384 PolarHBondContact O-OG1 3.16Å; A380-T384 VanDerWaalsContact O-OG1 3.11Å
381	Y	97.5	Very high	95	Very high	7 Å²	7	45.8 Å²	45.8	3%	0.027	23%	0.233	C	C	.	.	H	α-helix	trans	-56.9	-47	175.5	-59.4	-34.1	0	0	0	112	F296 Y297 C300 V341 Y367 L377 V378 F383 T384 G385	F296-Y381 HydrophobicContact CB-CD1 3.73Å; F296-Y381 HydrophobicContact CB-CD2 3.82Å; F296-Y381 HydrophobicContact CB-CE1 4.11Å; F296-Y381 HydrophobicContact CB-CE2 4.2Å; F296-Y381 HydrophobicContact CB-CG 3.61Å; F296-Y381 AromaticContact CD2-CD2 3.89Å; F296-Y381 HydrophobicContact CD2-CD2 3.89Å; F296-Y381 HydrophobicContact CD2-CE2 4.32Å; F296-Y381 HydrophobicContact CD2-CG 4.41Å; F296-Y381 HydrophobicContact CG-CD2 4.02Å; F296-Y381 HydrophobicContact CG-CG 4.06Å; Y297-Y381 HydrophobicContact CD1-CE1 4.36Å; Y297-Y381 WeakPolarHBondContact CE1-OH 3.05Å; C300-Y381 WeakPolarHBondContact SG-CD1 3.22Å; V341-Y381 HydrophobicContact CG2-CE2 4.3Å; Y367-Y381 VanDerWaalsContact CE1-OH 3.29Å; Y367-Y381 WeakPolarHBondContact CE1-OH 3.46Å; Y367-Y381 PolarHBondContact OH-OH 3.16Å; L377-Y381 HydrophobicContact CB-CD2 4.45Å; L377-Y381 HydrophobicContact CB-CE1 4.13Å; L377-Y381 HydrophobicContact CB-CE2 3.77Å; L377-Y381 WeakPolarHBondContact CD1-OH 3.49Å; L377-Y381 PolarHBondContact O-N 2.76Å; V378-Y381 HydrophobicContact CG2-CD2 4.26Å; V378-Y381 WeakPolarHBondContact O-CB 3.36Å; V378-Y381 PolarHBondContact O-N 2.73Å; V378-Y381 VanDerWaalsContact O-N 3.15Å; Y381-F383 PolarHBondContact O-N 3.12Å; Y381-T384 PolarHBondContact O-N 3.14Å; Y381-T384 PolarHBondContact O-OG1 3.22Å; Y381-T384 VanDerWaalsContact O-OG1 3.05Å; Y381-G385 PolarHBondContact O-N 3.24Å
382	I	97.6	Very high	94.9	Very high	15 Å²	15	37.6 Å²	37.6	8%	0.077	20%	0.198	C	C	.	.	H	α-helix	trans	-61.5	-45.7	178.7	-68.3	171.3	0	0	0	110.9	F319 F330 L333 T334 V378 A380 G385 W386	F319-I382 HydrophobicContact CE2-CG2 4.34Å; F319-I382 HydrophobicContact CZ-CG2 4.21Å; F330-I382 HydrophobicContact CD1-CG2 3.87Å; F330-I382 HydrophobicContact CE1-CG2 4.04Å; L333-I382 HydrophobicContact CD2-CG1 4.31Å; L333-I382 HydrophobicContact CD2-CG2 3.95Å; L333-I382 HydrophobicContact CG-CD1 4.41Å; L333-I382 HydrophobicContact CG-CG1 4.31Å; T334-I382 HydrophobicContact CG2-CD1 4.44Å; T334-I382 WeakPolarHBondContact OG1-CD1 3.33Å; V378-I382 HydrophobicContact CG1-CD1 3.81Å; V378-I382 HydrophobicContact CG1-CG1 4.29Å; V378-I382 WeakPolarHBondContact O-CG1 3.47Å; V378-I382 PolarHBondContact O-N 3.37Å; A380-I382 VanDerWaalsContact C-N 3.34Å; A380-I382 PolarHBondContact O-N 3.11Å; I382-G385 PolarHBondContact O-N 3.03Å; I382-W386 VanDerWaalsContact O-CB 3.31Å; I382-W386 WeakPolarHBondContact O-CB 3.33Å; I382-W386 PolarHBondContact O-N 3.05Å
383	F	96.6	Very high	94.5	Very high	35 Å²	35	39.7 Å²	39.7	15%	0.154	20%	0.203	C	C	.	.	H	α-helix	trans	-62.2	-47.8	177.5	171.5	-110.6	0	0	0	112	Y303 T316 F319 P379 A380 Y381 W386 N387	Y303-F383 HydrophobicContact CE1-CE1 4.19Å; Y303-F383 AromaticContact CE2-CE1 3.97Å; Y303-F383 HydrophobicContact CE2-CE1 3.97Å; Y303-F383 HydrophobicContact CE2-CZ 4.42Å; Y303-F383 AromaticContact CZ-CE1 3.65Å; T316-F383 HydrophobicContact CG2-CE2 4.27Å; T316-F383 HydrophobicContact CG2-CZ 3.96Å; F319-F383 HydrophobicContact CB-CD2 4.23Å; F319-F383 HydrophobicContact CB-CE2 4.2Å; F319-F383 AromaticContact CD1-CD2 3.44Å; F319-F383 HydrophobicContact CD1-CD2 3.44Å; F319-F383 VanDerWaalsContact CD1-CD2 3.44Å; F319-F383 HydrophobicContact CD1-CE2 4.07Å; F319-F383 HydrophobicContact CD1-CG 4.41Å; F319-F383 HydrophobicContact CD2-CD2 4.22Å; F319-F383 HydrophobicContact CE1-CB 3.95Å; F319-F383 AromaticContact CE1-CD2 3.69Å; F319-F383 HydrophobicContact CE1-CD2 3.69Å; F319-F383 HydrophobicContact CE1-CG 4.26Å; F319-F383 HydrophobicContact CE2-CD2 4.45Å; F319-F383 AromaticContact CG-CD2 3.7Å; F319-F383 HydrophobicContact CG-CD2 3.7Å; F319-F383 HydrophobicContact CG-CE2 4.18Å; F319-F383 HydrophobicContact CZ-CB 3.99Å; F319-F383 HydrophobicContact CZ-CD2 4.21Å; P379-F383 PolarHBondContact O-N 3.17Å; A380-F383 PolarHBondContact O-N 2.96Å; Y381-F383 PolarHBondContact O-N 3.12Å; F383-W386 PolarHBondContact O-N 2.9Å; F383-N387 WeakPolarHBondContact O-CB 3.3Å; F383-N387 PolarHBondContact O-N 3.18Å
384	T	96.8	Very high	94	Very high	8 Å²	8	41.7 Å²	41.7	5%	0.049	22%	0.218	C	C	.	.	H	α-helix	trans	-66.8	-37.9	-179.9	57.7	0	0	0	0	112.3	F299 Y303 A380 Y381 N387 F388	F299-T384 WeakPolarHBondContact CB-OG1 3.36Å; Y303-T384 HydrophobicContact CD1-CG2 3.79Å; Y303-T384 HydrophobicContact CD2-CG2 4.35Å; Y303-T384 HydrophobicContact CG-CG2 3.65Å; A380-T384 WeakPolarHBondContact O-CG2 3.26Å; A380-T384 PolarHBondContact O-N 3.18Å; A380-T384 PolarHBondContact O-OG1 3.16Å; A380-T384 VanDerWaalsContact O-OG1 3.11Å; Y381-T384 PolarHBondContact O-N 3.14Å; Y381-T384 PolarHBondContact O-OG1 3.22Å; Y381-T384 VanDerWaalsContact O-OG1 3.05Å; T384-N387 PolarHBondContact O-N 3.39Å; T384-F388 VanDerWaalsContact O-CB 3.31Å; T384-F388 WeakPolarHBondContact O-CB 3.2Å; T384-F388 PolarHBondContact O-N 3.28Å
385	G	96.6	Very high	93.8	Very high	5 Å²	5	41.2 Å²	41.2	5%	0.052	22%	0.216	C	C	.	.	H	α-helix	trans	-65.6	-41.4	174.1	0	0	0	0	0	111.9	F299 Y381 I382 F388 L389	F299-G385 VanDerWaalsContact CD2-CA 3.44Å; Y381-G385 PolarHBondContact O-N 3.24Å; I382-G385 PolarHBondContact O-N 3.03Å; G385-F388 WeakPolarHBondContact O-CB 3.46Å; G385-F388 PolarHBondContact O-N 2.79Å; G385-L389 VanDerWaalsContact O-CG 3.32Å; G385-L389 WeakPolarHBondContact O-CG 3.31Å; G385-L389 PolarHBondContact O-N 3.35Å
386	W	95.5	Very high	93.5	Very high	42 Å²	42	41 Å²	41	16%	0.159	22%	0.22	C	C	.	.	H	α-helix	trans	-62.2	-44.3	173.1	-178.2	92.1	0	0	0	111.8	R315 R318 F319 I382 F383 F388 L389 E390	R315-W386 WeakPolarHBondContact O-CZ3 3.43Å; R318-W386 HydrophobicContact CB-CH2 3.83Å; R318-W386 HydrophobicContact CB-CZ2 4.34Å; F319-W386 HydrophobicContact CB-CD2 4.27Å; F319-W386 HydrophobicContact CB-CE3 3.84Å; F319-W386 HydrophobicContact CB-CH2 4.07Å; F319-W386 HydrophobicContact CB-CZ2 4.45Å; F319-W386 HydrophobicContact CB-CZ3 3.74Å; F319-W386 HydrophobicContact CD2-CB 3.99Å; F319-W386 AromaticContact CD2-CD2 3.58Å; F319-W386 HydrophobicContact CD2-CD2 3.58Å; F319-W386 AromaticContact CD2-CE3 3.82Å; F319-W386 HydrophobicContact CD2-CE3 3.82Å; F319-W386 AromaticContact CD2-CG 3.63Å; F319-W386 HydrophobicContact CD2-CG 3.63Å; F319-W386 HydrophobicContact CE2-CB 3.94Å; F319-W386 HydrophobicContact CE2-CD2 4.41Å; F319-W386 HydrophobicContact CE2-CG 4Å; F319-W386 HydrophobicContact CG-CD2 4.35Å; F319-W386 HydrophobicContact CG-CE3 4.19Å; I382-W386 VanDerWaalsContact O-CB 3.31Å; I382-W386 WeakPolarHBondContact O-CB 3.33Å; I382-W386 PolarHBondContact O-N 3.05Å; F383-W386 PolarHBondContact O-N 2.9Å; W386-F388 VanDerWaalsContact C-N 3.31Å; W386-F388 PolarHBondContact O-N 3.42Å; W386-L389 PolarHBondContact O-N 3.23Å; W386-E390 HydrophobicContact CH2-CG 4.2Å; W386-E390 HydrophobicContact CZ3-CB 4.43Å; W386-E390 HydrophobicContact CZ3-CG 4.43Å; W386-E390 VanDerWaalsContact O-CB 3.28Å; W386-E390 WeakPolarHBondContact O-CB 3.47Å; W386-E390 PolarHBondContact O-N 3.19Å
387	N	93.9	Very high	93.1	Very high	3 Å²	3	39 Å²	39	2%	0.016	21%	0.207	C	C	.	.	H	α-helix	trans	-62.4	-40.2	177.5	-169.1	-74.2	0	0	0	112	Y303 S310 R315 F383 T384 E390 T391	Y303-N387 HydrophobicContact CD2-CB 4.34Å; Y303-N387 HydrophobicContact CE2-CB 4.48Å; S310-N387 PolarHBondContact O-ND2 3.13Å; R315-N387 PolarHBondContact NH1-OD1 2.87Å; F383-N387 WeakPolarHBondContact O-CB 3.3Å; F383-N387 PolarHBondContact O-N 3.18Å; T384-N387 PolarHBondContact O-N 3.39Å; N387-E390 PolarHBondContact O-N 3.34Å; N387-T391 PolarHBondContact O-N 3.32Å; N387-T391 VanDerWaalsContact O-N 3.16Å; N387-T391 PolarHBondContact O-OG1 3.44Å; N387-T391 VanDerWaalsContact O-OG1 3.07Å
388	F	94.8	Very high	92.9	Very high	3 Å²	3	37.3 Å²	37.3	1%	0.013	20%	0.198	C	C	.	.	H	α-helix	trans	-60.4	-52.3	175.3	-173.7	-87.4	0	0	0	111.2	F298 F299 T302 T384 G385 W386 E390 T391 L392 Y403 L404 L407 Y429	F298-F388 HydrophobicContact CE1-CD2 4.5Å; F298-F388 AromaticContact CE1-CE2 3.64Å; F298-F388 HydrophobicContact CE1-CE2 3.64Å; F298-F388 AromaticContact CE1-CZ 3.88Å; F298-F388 HydrophobicContact CE1-CZ 3.88Å; F298-F388 HydrophobicContact CZ-CE2 4.3Å; F299-F388 HydrophobicContact CD1-CB 4.01Å; F299-F388 HydrophobicContact CD1-CD1 4.06Å; F299-F388 HydrophobicContact CD1-CD2 4.02Å; F299-F388 AromaticContact CD1-CG 3.76Å; F299-F388 HydrophobicContact CD1-CG 3.76Å; F299-F388 HydrophobicContact CE1-CB 4.25Å; F299-F388 AromaticContact CE1-CD1 3.58Å; F299-F388 HydrophobicContact CE1-CD1 3.58Å; F299-F388 HydrophobicContact CE1-CD2 4.33Å; F299-F388 AromaticContact CE1-CE1 3.99Å; F299-F388 HydrophobicContact CE1-CE1 3.99Å; F299-F388 AromaticContact CE1-CG 3.79Å; F299-F388 HydrophobicContact CE1-CG 3.79Å; F299-F388 HydrophobicContact CZ-CD1 4.47Å; T302-F388 HydrophobicContact CG2-CD2 3.79Å; T302-F388 HydrophobicContact CG2-CE2 3.85Å; T384-F388 VanDerWaalsContact O-CB 3.31Å; T384-F388 WeakPolarHBondContact O-CB 3.2Å; T384-F388 PolarHBondContact O-N 3.28Å; G385-F388 WeakPolarHBondContact O-CB 3.46Å; G385-F388 PolarHBondContact O-N 2.79Å; W386-F388 VanDerWaalsContact C-N 3.31Å; W386-F388 PolarHBondContact O-N 3.42Å; F388-E390 VanDerWaalsContact C-N 3.34Å; F388-E390 PolarHBondContact O-N 3.3Å; F388-T391 WeakPolarHBondContact O-CB 3.38Å; F388-T391 PolarHBondContact O-N 2.85Å; F388-T391 VanDerWaalsContact O-N 3.16Å; F388-L392 HydrophobicContact CD1-CD1 4.09Å; F388-L392 HydrophobicContact CD1-CG 4.44Å; F388-L392 HydrophobicContact CE1-CD1 3.57Å; F388-L392 HydrophobicContact CE1-CG 4.12Å; F388-L392 HydrophobicContact CZ-CD1 4.42Å; F388-L392 PolarHBondContact O-N 3.32Å; F388-L392 VanDerWaalsContact O-N 3.17Å; F388-Y403 AromaticContact CE1-CE1 3.93Å; F388-Y403 HydrophobicContact CE1-CE1 3.93Å; F388-Y403 AromaticContact CZ-CE1 3.53Å; F388-Y403 HydrophobicContact CZ-CE1 3.53Å; F388-L404 HydrophobicContact CE1-CD2 4.11Å; F388-L407 HydrophobicContact CE1-CD2 4.41Å; F388-L407 HydrophobicContact CZ-CD2 4.38Å; F388-Y429 AromaticContact CD2-CD2 3.86Å; F388-Y429 HydrophobicContact CD2-CD2 3.86Å; F388-Y429 HydrophobicContact CD2-CE1 4.49Å; F388-Y429 AromaticContact CD2-CE2 3.55Å; F388-Y429 HydrophobicContact CD2-CE2 3.55Å; F388-Y429 HydrophobicContact CD2-CG 4.43Å; F388-Y429 AromaticContact CD2-CZ 3.9Å; F388-Y429 HydrophobicContact CE1-CD2 4.31Å; F388-Y429 HydrophobicContact CE1-CE2 4.49Å; F388-Y429 HydrophobicContact CE2-CD1 4.2Å; F388-Y429 AromaticContact CE2-CD2 3.18Å; F388-Y429 HydrophobicContact CE2-CD2 3.18Å; F388-Y429 HydrophobicContact CE2-CE1 4.38Å; F388-Y429 AromaticContact CE2-CE2 3.41Å; F388-Y429 HydrophobicContact CE2-CE2 3.41Å; F388-Y429 VanDerWaalsContact CE2-CE2 3.41Å; F388-Y429 AromaticContact CE2-CG 3.61Å; F388-Y429 HydrophobicContact CE2-CG 3.61Å; F388-Y429 HydrophobicContact CG-CE2 4.15Å; F388-Y429 AromaticContact CZ-CD2 3.42Å; F388-Y429 HydrophobicContact CZ-CD2 3.42Å; F388-Y429 VanDerWaalsContact CZ-CD2 3.42Å; F388-Y429 AromaticContact CZ-CE2 3.88Å; F388-Y429 HydrophobicContact CZ-CE2 3.88Å; F388-Y429 HydrophobicContact CZ-CG 4.08Å
389	L	93.2	Very high	92.7	Very high	80 Å²	80	38.3 Å²	38.3	42%	0.419	20%	0.203	S	C	.	.	H	α-helix	trans	-64.7	-36.6	178.6	-67.4	176.3	0	0	0	112.6	G385 W386 T391 L392 K393 L404	G385-L389 VanDerWaalsContact O-CG 3.32Å; G385-L389 WeakPolarHBondContact O-CG 3.31Å; G385-L389 PolarHBondContact O-N 3.35Å; W386-L389 PolarHBondContact O-N 3.23Å; L389-T391 PolarHBondContact O-N 3.18Å; L389-L392 PolarHBondContact O-N 2.94Å; L389-L392 VanDerWaalsContact O-N 3.14Å; L389-K393 PolarHBondContact O-N 3.09Å; L389-L404 HydrophobicContact CD2-CD1 3.92Å; L389-L404 HydrophobicContact CD2-CD2 4.14Å
390	E	90.2	Very high	92.6	Very high	26 Å²	26	35 Å²	35	12%	0.121	18%	0.182	C	C	.	.	H	α-helix	trans	-60.5	-34.7	175.5	-175.1	60.6	-158	0	0	111.9	R318 W386 N387 F388 K393	R318-E390 IonicContact CZ-OE1 2.74Å; R318-E390 IonicContact NH1-OE1 3.64Å; R318-E390 PolarHBondContact NH1-OE1 3.38Å; R318-E390 IonicContact NH2-OE1 3.95Å; R318-E390 PolarHBondContact NH2-OE1 3.09Å; W386-E390 HydrophobicContact CH2-CG 4.2Å; W386-E390 HydrophobicContact CZ3-CB 4.43Å; W386-E390 HydrophobicContact CZ3-CG 4.43Å; W386-E390 VanDerWaalsContact O-CB 3.28Å; W386-E390 WeakPolarHBondContact O-CB 3.47Å; W386-E390 PolarHBondContact O-N 3.19Å; N387-E390 PolarHBondContact O-N 3.34Å; F388-E390 VanDerWaalsContact C-N 3.34Å; F388-E390 PolarHBondContact O-N 3.3Å; E390-K393 WeakPolarHBondContact O-CB 3.38Å; E390-K393 WeakPolarHBondContact OE2-CD 3.39Å; E390-K393 VanDerWaalsContact OE2-CE 3.28Å; E390-K393 WeakPolarHBondContact OE2-CE 3.34Å; E390-K393 IonicContact OE2-NZ 3.72Å; E390-K393 PolarHBondContact OE2-NZ 3.16Å
391	T	88.7	Confident	92.5	Very high	6 Å²	6	37 Å²	37	4%	0.037	19%	0.186	C	C	.	.	H	α-helix	trans	-71.8	-39.2	175	-60.6	0	0	0	0	111.6	R315 N387 F388 L389 K393 S394 Y429 M433	R315-T391 PolarHBondContact NH1-OG1 3.3Å; R315-T391 PolarHBondContact NH2-OG1 3.4Å; N387-T391 PolarHBondContact O-N 3.32Å; N387-T391 VanDerWaalsContact O-N 3.16Å; N387-T391 PolarHBondContact O-OG1 3.44Å; N387-T391 VanDerWaalsContact O-OG1 3.07Å; F388-T391 WeakPolarHBondContact O-CB 3.38Å; F388-T391 PolarHBondContact O-N 2.85Å; F388-T391 VanDerWaalsContact O-N 3.16Å; L389-T391 PolarHBondContact O-N 3.18Å; T391-K393 PolarHBondContact O-N 3.22Å; T391-S394 PolarHBondContact O-N 2.79Å; T391-S394 PolarHBondContact O-OG 2.96Å; T391-S394 VanDerWaalsContact O-OG 3.09Å; T391-Y429 WeakPolarHBondContact CB-OH 3.42Å; T391-Y429 HydrophobicContact CG2-CE2 3.91Å; T391-Y429 WeakPolarHBondContact CG2-OH 3.27Å; T391-Y429 PolarHBondContact OG1-OH 2.79Å; T391-M433 HydrophobicContact CG2-CB 4.24Å; T391-M433 HydrophobicContact CG2-CE 3.46Å; T391-M433 VanDerWaalsContact CG2-CE 3.46Å; T391-M433 HydrophobicContact CG2-CG 3.46Å; T391-M433 VanDerWaalsContact CG2-CG 3.46Å; T391-M433 HydrophobicContact CG2-SD 3.88Å
392	L	89.1	Confident	92.4	Very high	12 Å²	12	37.6 Å²	37.6	6%	0.063	19%	0.191	C	C	.	.	H	α-helix	trans	-65.3	-20.1	178	-70.6	-174	0	0	0	113.6	F388 L389 S394 R395 S400 Y403 L404 Y429	F388-L392 HydrophobicContact CD1-CD1 4.09Å; F388-L392 HydrophobicContact CD1-CG 4.44Å; F388-L392 HydrophobicContact CE1-CD1 3.57Å; F388-L392 HydrophobicContact CE1-CG 4.12Å; F388-L392 HydrophobicContact CZ-CD1 4.42Å; F388-L392 PolarHBondContact O-N 3.32Å; F388-L392 VanDerWaalsContact O-N 3.17Å; L389-L392 PolarHBondContact O-N 2.94Å; L389-L392 VanDerWaalsContact O-N 3.14Å; L392-S394 PolarHBondContact O-N 3.1Å; L392-R395 WeakPolarHBondContact O-CB 3.29Å; L392-R395 PolarHBondContact O-N 3.24Å; L392-S400 PolarHBondContact O-OG 3.43Å; L392-Y403 HydrophobicContact CD1-CD1 4.13Å; L392-L404 HydrophobicContact CD1-CD1 4.44Å; L392-L404 HydrophobicContact CD1-CD2 4.06Å; L392-L404 HydrophobicContact CD1-CG 4.12Å; L392-Y429 HydrophobicContact CD2-CD2 4.22Å; L392-Y429 HydrophobicContact CD2-CE2 4.49Å
393	K	86.6	Confident	92.4	Very high	142 Å²	142	37.1 Å²	37.1	62%	0.617	19%	0.189	S	C	*	.	T	Hydrogen-bonded Turn	trans	-58.5	-17.5	175.9	-69.6	179.9	-178	173.3	0	114.8	L389 E390 T391 R395	L389-K393 PolarHBondContact O-N 3.09Å; E390-K393 WeakPolarHBondContact O-CB 3.38Å; E390-K393 WeakPolarHBondContact OE2-CD 3.39Å; E390-K393 VanDerWaalsContact OE2-CE 3.28Å; E390-K393 WeakPolarHBondContact OE2-CE 3.34Å; E390-K393 IonicContact OE2-NZ 3.72Å; E390-K393 PolarHBondContact OE2-NZ 3.16Å; T391-K393 PolarHBondContact O-N 3.22Å; K393-R395 PolarHBondContact O-N 3.45Å
394	S	84.5	Confident	92.4	Very high	67 Å²	67	37.7 Å²	37.7	47%	0.469	19%	0.193	S	C	.	.	T	Hydrogen-bonded Turn	trans	-76.2	-9.2	173	65.3	0	0	0	0	113.5	T391 L392 P434	T391-S394 PolarHBondContact O-N 2.79Å; T391-S394 PolarHBondContact O-OG 2.96Å; T391-S394 VanDerWaalsContact O-OG 3.09Å; L392-S394 PolarHBondContact O-N 3.1Å; S394-P434 WeakPolarHBondContact OG-CD 3.46Å; S394-P434 WeakPolarHBondContact OG-CG 3.4Å
395	R	88.4	Confident	92.4	Very high	67 Å²	67	40.6 Å²	40.6	25%	0.253	21%	0.211	S	C	.	.	S	Bend	trans	-104.1	164.9	175.2	-61.5	-57.8	-175.8	175.4	-3.6	110.2	L392 K393 H432	L392-R395 WeakPolarHBondContact O-CB 3.29Å; L392-R395 PolarHBondContact O-N 3.24Å; K393-R395 PolarHBondContact O-N 3.45Å; R395-H432 HydrophobicContact CG-CB 4.39Å; R395-H432 PolarHBondContact NE-O 3.38Å; R395-H432 VanDerWaalsContact NH2-CA 3.33Å; R395-H432 PolarHBondContact NH2-O 3.47Å
396	S	89.3	Confident	92.5	Very high	41 Å²	41	40.7 Å²	40.7	29%	0.287	21%	0.211	S	C	.	.			trans	-67.2	154.7	176.1	62.9	0	0	0	0	111.2	D207 F398 M399 S400	D207-S396 VanDerWaalsContact CG-CB 3.44Å; D207-S396 VanDerWaalsContact OD1-CB 3.22Å; D207-S396 WeakPolarHBondContact OD1-CB 3.31Å; D207-S396 WeakPolarHBondContact OD2-CB 3.28Å; D207-S396 PolarHBondContact OD2-OG 2.9Å; S396-F398 PolarHBondContact O-N 3.42Å; S396-M399 PolarHBondContact O-N 3.05Å; S396-M399 WeakPolarHBondContact OG-CB 3.33Å; S396-M399 PolarHBondContact OG-N 3.18Å; S396-S400 PolarHBondContact O-N 3.18Å; S396-S400 PolarHBondContact O-OG 3.31Å
397	F	88.9	Confident	92.7	Very high	87 Å²	87	38.8 Å²	38.8	38%	0.382	20%	0.204	S	C	.	.	H	α-helix	trans	-58.2	-48.4	-178.3	172.4	-97.2	0	0	0	111.7	V227 V237 M399 S400 L401	V227-F397 HydrophobicContact CG2-CB 4.19Å; V227-F397 HydrophobicContact CG2-CD1 4.29Å; V227-F397 HydrophobicContact CG2-CG 4.08Å; V237-F397 HydrophobicContact CG1-CE1 3.69Å; V237-F397 HydrophobicContact CG1-CZ 4.21Å; F397-M399 VanDerWaalsContact C-N 3.32Å; F397-M399 PolarHBondContact O-N 3.3Å; F397-S400 PolarHBondContact O-N 3.47Å; F397-L401 HydrophobicContact CE1-CD2 4.38Å; F397-L401 WeakPolarHBondContact O-CB 3.47Å; F397-L401 PolarHBondContact O-N 2.97Å
398	F	92.6	Very high	92.8	Very high	8 Å²	8	41.6 Å²	41.6	4%	0.035	22%	0.221	C	C	.	.	H	α-helix	trans	-65.4	-36.1	-178.6	-58.9	-61.8	0	0	0	112	A203 M206 D207 W210 V237 F240 S396 L401 A402	A203-F398 HydrophobicContact CB-CB 3.72Å; M206-F398 HydrophobicContact CB-CB 4.37Å; M206-F398 HydrophobicContact CB-CD1 4.25Å; M206-F398 HydrophobicContact CB-CD2 3.56Å; M206-F398 HydrophobicContact CB-CE1 4.47Å; M206-F398 HydrophobicContact CB-CE2 3.84Å; M206-F398 HydrophobicContact CB-CG 3.81Å; M206-F398 HydrophobicContact CB-CZ 4.3Å; M206-F398 HydrophobicContact CE-CD1 3.61Å; M206-F398 HydrophobicContact CE-CE1 3.45Å; M206-F398 VanDerWaalsContact CE-CE1 3.45Å; M206-F398 HydrophobicContact CE-CG 4.35Å; M206-F398 HydrophobicContact CE-CZ 4.09Å; M206-F398 HydrophobicContact SD-CD1 3.92Å; M206-F398 HydrophobicContact SD-CE1 4.34Å; M206-F398 HydrophobicContact SD-CG 4.2Å; D207-F398 VanDerWaalsContact OD1-CD2 3.26Å; D207-F398 WeakPolarHBondContact OD1-CD2 3.49Å; W210-F398 HydrophobicContact CB-CE2 3.99Å; W210-F398 HydrophobicContact CD2-CE2 4.37Å; W210-F398 HydrophobicContact CD2-CZ 4.3Å; W210-F398 HydrophobicContact CE3-CZ 4.17Å; W210-F398 HydrophobicContact CG-CE2 4.12Å; V237-F398 HydrophobicContact CG1-CE1 4.44Å; F240-F398 HydrophobicContact CD1-CE1 4.46Å; F240-F398 AromaticContact CD1-CZ 3.88Å; F240-F398 HydrophobicContact CD1-CZ 3.88Å; F240-F398 HydrophobicContact CE1-CE1 4.3Å; F240-F398 HydrophobicContact CE1-CE2 4.09Å; F240-F398 AromaticContact CE1-CZ 3.57Å; F240-F398 HydrophobicContact CE1-CZ 3.57Å; S396-F398 PolarHBondContact O-N 3.42Å; F398-L401 PolarHBondContact O-N 2.67Å; F398-A402 WeakPolarHBondContact O-CB 3.22Å; F398-A402 PolarHBondContact O-N 2.76Å
399	M	92.9	Very high	93	Very high	22 Å²	22	46 Å²	46	11%	0.108	24%	0.244	C	C	.	.	H	α-helix	trans	-67.4	-43.1	175.6	-177	60.9	-139.9	0	0	111.9	F196 T200 A203 S396 F397 L401 A402 Y403	F196-M399 HydrophobicContact CD2-CE 4.47Å; F196-M399 HydrophobicContact CE1-CE 4.33Å; F196-M399 HydrophobicContact CE2-CE 3.3Å; F196-M399 HydrophobicContact CZ-CE 3.23Å; T200-M399 HydrophobicContact CG2-CE 3.48Å; T200-M399 VanDerWaalsContact CG2-CE 3.48Å; T200-M399 HydrophobicContact CG2-SD 3.6Å; T200-M399 VanDerWaalsContact CG2-SD 3.6Å; A203-M399 HydrophobicContact CB-CB 4.44Å; S396-M399 PolarHBondContact O-N 3.05Å; S396-M399 WeakPolarHBondContact OG-CB 3.33Å; S396-M399 PolarHBondContact OG-N 3.18Å; F397-M399 VanDerWaalsContact C-N 3.32Å; F397-M399 PolarHBondContact O-N 3.3Å; M399-L401 VanDerWaalsContact C-N 3.31Å; M399-L401 PolarHBondContact O-N 3.27Å; M399-A402 PolarHBondContact O-N 3.28Å; M399-Y403 WeakPolarHBondContact O-CB 3.42Å; M399-Y403 PolarHBondContact O-N 2.91Å
400	S	94.2	Very high	93.1	Very high	16 Å²	16	42.5 Å²	42.5	11%	0.112	23%	0.227	C	C	.	.	H	α-helix	trans	-62.3	-39.2	173.7	-65.3	0	0	0	0	111.9	L392 S396 F397 Y403 L404	L392-S400 PolarHBondContact O-OG 3.43Å; S396-S400 PolarHBondContact O-N 3.18Å; S396-S400 PolarHBondContact O-OG 3.31Å; F397-S400 PolarHBondContact O-N 3.47Å; S400-Y403 PolarHBondContact O-N 3.02Å; S400-L404 WeakPolarHBondContact O-CB 3.22Å; S400-L404 VanDerWaalsContact O-CG 3.25Å; S400-L404 WeakPolarHBondContact O-CG 3.45Å; S400-L404 PolarHBondContact O-N 2.8Å
401	L	93.9	Very high	93.4	Very high	86 Å²	86	41.3 Å²	41.3	45%	0.45	22%	0.222	S	C	.	.	H	α-helix	trans	-63.6	-50	176.4	-177.7	62.1	0	0	0	111.3	F397 F398 M399 Y403 L404 T405	F397-L401 HydrophobicContact CE1-CD2 4.38Å; F397-L401 WeakPolarHBondContact O-CB 3.47Å; F397-L401 PolarHBondContact O-N 2.97Å; F398-L401 PolarHBondContact O-N 2.67Å; M399-L401 VanDerWaalsContact C-N 3.31Å; M399-L401 PolarHBondContact O-N 3.27Å; L401-Y403 VanDerWaalsContact C-N 3.29Å; L401-Y403 PolarHBondContact O-N 2.99Å; L401-L404 PolarHBondContact O-N 3.18Å; L401-L404 VanDerWaalsContact O-N 3.17Å; L401-T405 PolarHBondContact O-N 3.09Å; L401-T405 PolarHBondContact O-OG1 3.16Å; L401-T405 VanDerWaalsContact O-OG1 3.11Å
402	A	96.1	Very high	93.8	Very high	18 Å²	18	41.7 Å²	41.7	15%	0.149	22%	0.223	C	C	.	.	H	α-helix	trans	-56.2	-44.1	176.8	0	0	0	0	0	111.9	F398 M399 C406	F398-A402 WeakPolarHBondContact O-CB 3.22Å; F398-A402 PolarHBondContact O-N 2.76Å; M399-A402 PolarHBondContact O-N 3.28Å; A402-C406 PolarHBondContact O-N 3.31Å; A402-C406 VanDerWaalsContact O-N 3.12Å; A402-C406 PolarHBondContact O-SG 3.1Å
403	Y	97.3	Very high	94.1	Very high	5 Å²	5	43.1 Å²	43.1	2%	0.02	23%	0.233	C	C	.	.	H	α-helix	trans	-62.1	-49	175.4	178.1	-88.5	0	0	0	112.4	W193 F196 F388 L392 M399 S400 L401 T405 C406 L407 P425 M428	W193-Y403 HydrophobicContact CH2-CE2 4.22Å; W193-Y403 HydrophobicContact CZ3-CE2 4.33Å; F196-Y403 AromaticContact CE2-CD2 3.81Å; F196-Y403 HydrophobicContact CE2-CD2 3.81Å; F196-Y403 HydrophobicContact CE2-CG 4.31Å; F196-Y403 HydrophobicContact CZ-CD2 4.16Å; F388-Y403 AromaticContact CE1-CE1 3.93Å; F388-Y403 HydrophobicContact CE1-CE1 3.93Å; F388-Y403 AromaticContact CZ-CE1 3.53Å; F388-Y403 HydrophobicContact CZ-CE1 3.53Å; L392-Y403 HydrophobicContact CD1-CD1 4.13Å; M399-Y403 WeakPolarHBondContact O-CB 3.42Å; M399-Y403 PolarHBondContact O-N 2.91Å; S400-Y403 PolarHBondContact O-N 3.02Å; L401-Y403 VanDerWaalsContact C-N 3.29Å; L401-Y403 PolarHBondContact O-N 2.99Å; Y403-T405 VanDerWaalsContact C-N 3.35Å; Y403-T405 PolarHBondContact O-N 3.25Å; Y403-C406 PolarHBondContact O-N 3.34Å; Y403-L407 HydrophobicContact CE1-CB 4.23Å; Y403-L407 HydrophobicContact CE1-CD2 4.2Å; Y403-L407 WeakPolarHBondContact O-CB 3.27Å; Y403-L407 PolarHBondContact O-N 3.23Å; Y403-P425 PolarHBondContact OH-O 2.91Å; Y403-M428 HydrophobicContact CD2-CB 4.41Å; Y403-M428 HydrophobicContact CE2-CB 3.82Å
404	L	97.4	Very high	94.4	Very high	47 Å²	47	38.3 Å²	38.3	25%	0.246	21%	0.213	C	C	.	.	H	α-helix	trans	-64.5	-38.7	-178	-74	170.4	0	0	0	111.8	F388 L389 L392 S400 L401 L407 V408	F388-L404 HydrophobicContact CE1-CD2 4.11Å; L389-L404 HydrophobicContact CD2-CD1 3.92Å; L389-L404 HydrophobicContact CD2-CD2 4.14Å; L392-L404 HydrophobicContact CD1-CD1 4.44Å; L392-L404 HydrophobicContact CD1-CD2 4.06Å; L392-L404 HydrophobicContact CD1-CG 4.12Å; S400-L404 WeakPolarHBondContact O-CB 3.22Å; S400-L404 VanDerWaalsContact O-CG 3.25Å; S400-L404 WeakPolarHBondContact O-CG 3.45Å; S400-L404 PolarHBondContact O-N 2.8Å; L401-L404 PolarHBondContact O-N 3.18Å; L401-L404 VanDerWaalsContact O-N 3.17Å; L404-L407 HydrophobicContact CD2-CD2 4.4Å; L404-L407 WeakPolarHBondContact O-CB 3.44Å; L404-L407 PolarHBondContact O-N 3.39Å; L404-V408 VanDerWaalsContact O-CG2 3.3Å; L404-V408 WeakPolarHBondContact O-CG2 3.32Å; L404-V408 PolarHBondContact O-N 2.96Å
405	T	97.6	Very high	94.8	Very high	70 Å²	70	37.7 Å²	37.7	43%	0.429	20%	0.203	S	C	.	.	H	α-helix	trans	-60.7	-47.2	173.3	-61.2	0	0	0	0	111	L401 Y403 L407 V408 L409	L401-T405 PolarHBondContact O-N 3.09Å; L401-T405 PolarHBondContact O-OG1 3.16Å; L401-T405 VanDerWaalsContact O-OG1 3.11Å; Y403-T405 VanDerWaalsContact C-N 3.35Å; Y403-T405 PolarHBondContact O-N 3.25Å; T405-L407 VanDerWaalsContact C-N 3.33Å; T405-L407 PolarHBondContact O-N 3.4Å; T405-V408 PolarHBondContact O-N 3.38Å; T405-L409 HydrophobicContact CG2-CD1 4.01Å; T405-L409 HydrophobicContact CG2-CG 4.49Å; T405-L409 WeakPolarHBondContact O-CB 3.32Å; T405-L409 VanDerWaalsContact O-CG 3.31Å; T405-L409 WeakPolarHBondContact O-CG 3.37Å; T405-L409 PolarHBondContact O-N 3.46Å
406	C	98.2	Very high	95	Very high	7 Å²	7	35.9 Å²	35.9	5%	0.047	20%	0.198	C	C	.	.	H	α-helix	trans	-65	-37.6	177.6	-65.4	0	0	0	0	112	V192 W193 F196 A402 Y403 L409 A410	V192-C406 HydrophobicContact CG1-CB 3.74Å; V192-C406 WeakPolarHBondContact CG1-O 3.35Å; W193-C406 HydrophobicContact CZ3-CB 4.45Å; F196-C406 HydrophobicContact CB-CB 4.23Å; F196-C406 HydrophobicContact CD2-CB 4.33Å; A402-C406 PolarHBondContact O-N 3.31Å; A402-C406 VanDerWaalsContact O-N 3.12Å; A402-C406 PolarHBondContact O-SG 3.1Å; Y403-C406 PolarHBondContact O-N 3.34Å; C406-L409 PolarHBondContact O-N 3.25Å; C406-A410 VanDerWaalsContact O-CB 3.23Å; C406-A410 WeakPolarHBondContact O-CB 3.41Å; C406-A410 PolarHBondContact O-N 2.97Å
407	L	98.2	Very high	95.2	Very high	2 Å²	2	34.2 Å²	34.2	1%	0.01	19%	0.186	C	C	.	.	H	α-helix	trans	-59.8	-48.6	174.8	174.3	63.5	0	0	0	111.5	F298 F299 F388 Y403 L404 T405 A410 T411 P425	F298-L407 HydrophobicContact CD1-CD1 3.42Å; F298-L407 VanDerWaalsContact CD1-CD1 3.42Å; F298-L407 HydrophobicContact CD1-CD2 3.69Å; F298-L407 HydrophobicContact CD1-CG 4.15Å; F298-L407 HydrophobicContact CD2-CD1 4.23Å; F298-L407 HydrophobicContact CE1-CD1 3.44Å; F298-L407 VanDerWaalsContact CE1-CD1 3.44Å; F298-L407 HydrophobicContact CE1-CD2 3.67Å; F298-L407 HydrophobicContact CE1-CG 4.21Å; F298-L407 HydrophobicContact CE2-CD1 4.26Å; F298-L407 HydrophobicContact CG-CD1 3.83Å; F298-L407 HydrophobicContact CZ-CD1 3.88Å; F299-L407 HydrophobicContact CE1-CD2 4.12Å; F388-L407 HydrophobicContact CE1-CD2 4.41Å; F388-L407 HydrophobicContact CZ-CD2 4.38Å; Y403-L407 HydrophobicContact CE1-CB 4.23Å; Y403-L407 HydrophobicContact CE1-CD2 4.2Å; Y403-L407 WeakPolarHBondContact O-CB 3.27Å; Y403-L407 PolarHBondContact O-N 3.23Å; L404-L407 HydrophobicContact CD2-CD2 4.4Å; L404-L407 WeakPolarHBondContact O-CB 3.44Å; L404-L407 PolarHBondContact O-N 3.39Å; T405-L407 VanDerWaalsContact C-N 3.33Å; T405-L407 PolarHBondContact O-N 3.4Å; L407-A410 PolarHBondContact O-N 3.38Å; L407-T411 HydrophobicContact CD1-CG2 3.85Å; L407-T411 WeakPolarHBondContact O-CB 3.35Å; L407-T411 WeakPolarHBondContact O-CG2 3.18Å; L407-T411 PolarHBondContact O-N 2.86Å; L407-T411 PolarHBondContact O-OG1 3.38Å; L407-P425 HydrophobicContact CD1-CB 3.74Å; L407-P425 HydrophobicContact CD1-CG 4.32Å
408	V	98	Very high	95.5	Very high	62 Å²	62	30.8 Å²	30.8	38%	0.376	17%	0.171	S	C	.	.	H	α-helix	trans	-60.2	-48.9	178	165.1	0	0	0	0	110.3	V295 L404 T405 A410 T411 I412	V295-V408 HydrophobicContact CG2-CG2 4.46Å; L404-V408 VanDerWaalsContact O-CG2 3.3Å; L404-V408 WeakPolarHBondContact O-CG2 3.32Å; L404-V408 PolarHBondContact O-N 2.96Å; T405-V408 PolarHBondContact O-N 3.38Å; V408-A410 VanDerWaalsContact C-N 3.31Å; V408-A410 PolarHBondContact O-N 2.92Å; V408-T411 PolarHBondContact O-N 3.19Å; V408-I412 HydrophobicContact CB-CD1 4.29Å; V408-I412 HydrophobicContact CG1-CD1 3.47Å; V408-I412 VanDerWaalsContact CG1-CD1 3.47Å; V408-I412 HydrophobicContact CG1-CG1 4.2Å; V408-I412 HydrophobicContact CG2-CD1 4.46Å; V408-I412 WeakPolarHBondContact O-CB 3.47Å; V408-I412 WeakPolarHBondContact O-CG1 3.24Å; V408-I412 PolarHBondContact O-N 3.47Å
409	L	97.1	Very high	95.6	Very high	94 Å²	94	31.5 Å²	31.5	49%	0.492	17%	0.174	S	C	.	.	H	α-helix	trans	-64.6	-32.6	179.4	-69.3	174.7	0	0	0	113.2	V192 T405 C406 P413	V192-L409 HydrophobicContact CG1-CB 3.93Å; V192-L409 HydrophobicContact CG2-CB 4.11Å; T405-L409 HydrophobicContact CG2-CD1 4.01Å; T405-L409 HydrophobicContact CG2-CG 4.49Å; T405-L409 WeakPolarHBondContact O-CB 3.32Å; T405-L409 VanDerWaalsContact O-CG 3.31Å; T405-L409 WeakPolarHBondContact O-CG 3.37Å; T405-L409 PolarHBondContact O-N 3.46Å; C406-L409 PolarHBondContact O-N 3.25Å; L409-P413 VanDerWaalsContact O-CD 3.25Å; L409-P413 WeakPolarHBondContact O-CD 3.45Å; L409-P413 WeakPolarHBondContact O-CG 3.49Å
410	A	96.4	Very high	95.8	Very high	8 Å²	8	31.4 Å²	31.4	7%	0.066	17%	0.173	C	C	.	.	H	α-helix	trans	-78.5	-28.4	179.2	0	0	0	0	0	113.2	V192 W193 C406 L407 V408	V192-A410 HydrophobicContact CG1-CB 4.16Å; W193-A410 HydrophobicContact CZ2-CB 4.35Å; C406-A410 VanDerWaalsContact O-CB 3.23Å; C406-A410 WeakPolarHBondContact O-CB 3.41Å; C406-A410 PolarHBondContact O-N 2.97Å; L407-A410 PolarHBondContact O-N 3.38Å; V408-A410 VanDerWaalsContact C-N 3.31Å; V408-A410 PolarHBondContact O-N 2.92Å
411	T	96.4	Very high	95.8	Very high	1 Å²	1	32.5 Å²	32.5	1%	0.006	17%	0.174	C	C	.	.	H	α-helix	trans	-107.1	-44	-169.3	56.8	0	0	0	0	114.2	Q294 V295 L407 V408 Q414 F422	Q294-T411 WeakPolarHBondContact CB-O 3.23Å; Q294-T411 WeakPolarHBondContact CG-O 3.45Å; V295-T411 WeakPolarHBondContact CG2-OG1 3.44Å; L407-T411 HydrophobicContact CD1-CG2 3.85Å; L407-T411 WeakPolarHBondContact O-CB 3.35Å; L407-T411 WeakPolarHBondContact O-CG2 3.18Å; L407-T411 PolarHBondContact O-N 2.86Å; L407-T411 PolarHBondContact O-OG1 3.38Å; V408-T411 PolarHBondContact O-N 3.19Å; T411-Q414 WeakPolarHBondContact O-CB 3.41Å; T411-Q414 PolarHBondContact O-N 2.92Å; T411-F422 HydrophobicContact CG2-CD1 4.09Å; T411-F422 HydrophobicContact CG2-CE1 3.94Å
412	I	97.2	Very high	96	Very high	13 Å²	13	28.4 Å²	28.4	7%	0.067	15%	0.153	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63	-41.2	-174.4	-64.4	-173.3	0	0	0	113.3	F290 H291 F292 V295 V408 Q414	F290-I412 HydrophobicContact CD1-CG2 4.48Å; H291-I412 WeakPolarHBondContact CA-O 3.26Å; H291-I412 WeakPolarHBondContact CB-O 3.27Å; H291-I412 PolarHBondContact N-O 2.86Å; F292-I412 HydrophobicContact CD1-CD1 3.53Å; F292-I412 HydrophobicContact CE1-CD1 3.78Å; F292-I412 HydrophobicContact CG-CD1 4.29Å; V295-I412 HydrophobicContact CG2-CD1 4.1Å; V295-I412 HydrophobicContact CG2-CG1 3.74Å; V408-I412 HydrophobicContact CB-CD1 4.29Å; V408-I412 HydrophobicContact CG1-CD1 3.47Å; V408-I412 VanDerWaalsContact CG1-CD1 3.47Å; V408-I412 HydrophobicContact CG1-CG1 4.2Å; V408-I412 HydrophobicContact CG2-CD1 4.46Å; V408-I412 WeakPolarHBondContact O-CB 3.47Å; V408-I412 WeakPolarHBondContact O-CG1 3.24Å; V408-I412 PolarHBondContact O-N 3.47Å; I412-Q414 PolarHBondContact O-N 3.47Å; I412-Q414 VanDerWaalsContact O-N 3.07Å
413	P	95.6	Very high	96.1	Very high	43 Å²	43	27.7 Å²	27.7	28%	0.279	15%	0.147	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.6	-14.4	179.7	-27.2	38.7	0	0	0	114.9	A288 C289 L409	A288-P413 HydrophobicContact CB-CB 4.4Å; C289-P413 PolarHBondContact N-O 3.29Å; C289-P413 VanDerWaalsContact O-CA 3.24Å; C289-P413 WeakPolarHBondContact O-CA 3.16Å; L409-P413 VanDerWaalsContact O-CD 3.25Å; L409-P413 WeakPolarHBondContact O-CD 3.45Å; L409-P413 WeakPolarHBondContact O-CG 3.49Å
414	Q	92.8	Very high	96.2	Very high	40 Å²	40	28.2 Å²	28.2	19%	0.187	15%	0.149	C	C	.	.			trans	-82.7	116	-173.7	-54.2	-61.9	-22.9	0	0	111.4	H291 Q294 T411 I412 Y421	H291-Q414 WeakPolarHBondContact CB-O 3.29Å; H291-Q414 PolarHBondContact ND1-O 3.5Å; H291-Q414 VanDerWaalsContact ND1-O 3.16Å; Q294-Q414 PolarHBondContact NE2-O 2.85Å; T411-Q414 WeakPolarHBondContact O-CB 3.41Å; T411-Q414 PolarHBondContact O-N 2.92Å; I412-Q414 PolarHBondContact O-N 3.47Å; I412-Q414 VanDerWaalsContact O-N 3.07Å; Q414-Y421 HydrophobicContact CB-CD2 4Å; Q414-Y421 HydrophobicContact CB-CE2 4.21Å; Q414-Y421 HydrophobicContact CG-CD2 3.85Å; Q414-Y421 HydrophobicContact CG-CE2 4.31Å; Q414-Y421 HydrophobicContact CG-CG 4.43Å
415	E	92	Very high	96.2	Very high	55 Å²	55	26 Å²	26	26%	0.257	14%	0.138	S	C	.	.			trans	-71.1	-43.1	174	-162.5	-176.4	153.2	0	0	111.7	C289 H291 Y346 H348	C289-E415 WeakPolarHBondContact SG-CA 3.48Å; H291-E415 PolarHBondContact ND1-O 3.39Å; Y346-E415 HydrophobicContact CD1-CG 4.48Å; Y346-E415 HydrophobicContact CG-CG 4.37Å; H348-E415 HydrophobicContact CB-CG 4.38Å; H348-E415 IonicContact CD2-OE1 3.9Å; H348-E415 IonicContact CD2-OE2 2.95Å
416	L	93.1	Very high	96.3	Very high	29 Å²	29	22.7 Å²	22.7	15%	0.152	12%	0.118	C	C	.	.	S	Bend	trans	-76.8	128.4	-178.9	-179.4	62.1	0	0	0	111.6	Q294 H348 L351 E418 Y421	Q294-L416 PolarHBondContact NE2-O 2.95Å; H348-L416 HydrophobicContact CB-CB 4.11Å; H348-L416 HydrophobicContact CB-CD1 3.85Å; L351-L416 HydrophobicContact CB-CD1 3.85Å; L416-E418 HydrophobicContact CD2-CB 4.32Å; L416-E418 HydrophobicContact CG-CB 4.2Å; L416-E418 PolarHBondContact O-N 2.91Å; L416-Y421 HydrophobicContact CB-CE2 4.33Å; L416-Y421 WeakPolarHBondContact O-CE2 3.31Å
417	L	94.3	Very high	96.3	Very high	6 Å²	6	22.4 Å²	22.4	3%	0.031	12%	0.116	C	C	.	.			trans	-79.4	101.4	166.5	173.9	56.5	0	0	0	109.5	Y297 L351 W363 F419 F422	Y297-L417 HydrophobicContact CD2-CD1 3.73Å; Y297-L417 HydrophobicContact CD2-CD2 4.03Å; Y297-L417 HydrophobicContact CD2-CG 4.36Å; Y297-L417 HydrophobicContact CE2-CD2 4.22Å; Y297-L417 HydrophobicContact CG-CD1 4.19Å; Y297-L417 HydrophobicContact CG-CD2 4.46Å; L351-L417 HydrophobicContact CD2-CB 4.17Å; W363-L417 HydrophobicContact CE3-CD2 4Å; W363-L417 HydrophobicContact CZ3-CD2 4.17Å; L417-F419 HydrophobicContact CD1-CD1 4.45Å; L417-F419 HydrophobicContact CD1-CE1 4.26Å; L417-F422 HydrophobicContact CD1-CE2 4.09Å; L417-F422 HydrophobicContact CD1-CZ 4.07Å
418	E	93.4	Very high	96.2	Very high	14 Å²	14	22.3 Å²	22.3	7%	0.065	12%	0.115	C	C	.	.			trans	-135.9	127.6	175.8	-166.1	172.5	-177.1	0	0	110.2	L416 R420 Y421	L416-E418 HydrophobicContact CD2-CB 4.32Å; L416-E418 HydrophobicContact CG-CB 4.2Å; L416-E418 PolarHBondContact O-N 2.91Å; E418-R420 HydrophobicContact CG-CB 4.3Å; E418-R420 HydrophobicContact CG-CG 4.32Å; E418-R420 PolarHBondContact O-N 3.31Å; E418-R420 VanDerWaalsContact O-N 3.14Å; E418-R420 WeakPolarHBondContact OE1-CD 3.16Å; E418-R420 IonicContact OE1-CZ 3.79Å; E418-R420 IonicContact OE1-NE 2.77Å; E418-R420 IonicContact OE1-NH1 3.79Å; E418-R420 PolarHBondContact OE1-NH1 3.19Å; E418-Y421 HydrophobicContact CB-CD2 4.14Å; E418-Y421 HydrophobicContact CB-CE1 4.35Å; E418-Y421 HydrophobicContact CB-CE2 3.81Å; E418-Y421 PolarHBondContact O-N 3.34Å; E418-Y421 VanDerWaalsContact O-N 3.16Å; E418-Y421 PolarHBondContact OE2-OH 3.48Å
419	F	96.1	Very high	96.2	Very high	24 Å²	24	19.5 Å²	19.5	11%	0.105	10%	0.098	C	C	.	.	G	3₁₀ helix	trans	-67.7	-17.2	-172.9	-67.4	-23.6	0	0	0	114.1	V143 F301 P359 I362 L417 Y421 F422 W477	V143-F419 HydrophobicContact CG1-CB 4.27Å; V143-F419 HydrophobicContact CG2-CB 4.29Å; F301-F419 HydrophobicContact CD2-CB 4.39Å; F301-F419 AromaticContact CD2-CD1 3.87Å; F301-F419 HydrophobicContact CD2-CD1 3.87Å; F301-F419 HydrophobicContact CD2-CD2 4.48Å; F301-F419 HydrophobicContact CD2-CE1 4.25Å; F301-F419 HydrophobicContact CD2-CG 4Å; F301-F419 HydrophobicContact CE2-CB 3.72Å; F301-F419 HydrophobicContact CE2-CD1 4.08Å; F301-F419 HydrophobicContact CE2-CD2 4.24Å; F301-F419 AromaticContact CE2-CG 3.76Å; F301-F419 HydrophobicContact CE2-CG 3.76Å; F301-F419 HydrophobicContact CZ-CB 4.4Å; P359-F419 HydrophobicContact CG-CD2 4.07Å; P359-F419 HydrophobicContact CG-CE2 4.2Å; P359-F419 HydrophobicContact CG-CG 4.31Å; I362-F419 HydrophobicContact CD1-CE2 3.57Å; I362-F419 HydrophobicContact CD1-CZ 3.46Å; I362-F419 VanDerWaalsContact CD1-CZ 3.46Å; L417-F419 HydrophobicContact CD1-CD1 4.45Å; L417-F419 HydrophobicContact CD1-CE1 4.26Å; F419-Y421 PolarHBondContact O-N 3.23Å; F419-F422 AromaticContact CD1-CD2 3.97Å; F419-F422 HydrophobicContact CD1-CD2 3.97Å; F419-F422 AromaticContact CD1-CE2 3.97Å; F419-F422 HydrophobicContact CD1-CE2 3.97Å; F419-F422 HydrophobicContact CE1-CE2 4.44Å; F419-F422 WeakPolarHBondContact O-CB 3.3Å; F419-F422 PolarHBondContact O-N 3.4Å; F419-W477 AromaticContact CD2-CE3 3.74Å; F419-W477 HydrophobicContact CD2-CE3 3.74Å; F419-W477 AromaticContact CD2-CZ3 3.58Å; F419-W477 HydrophobicContact CD2-CZ3 3.58Å; F419-W477 HydrophobicContact CE2-CE3 4.48Å; F419-W477 HydrophobicContact CE2-CZ3 4.01Å
420	R	95.8	Very high	96.1	Very high	20 Å²	20	15.1 Å²	15.1	8%	0.075	8%	0.075	C	C	.	.	G	3₁₀ helix	trans	-60.9	-33	174	-66.1	165.2	68.2	-159.2	-8.4	112.6	D40 V143 F147 Y152 D154 E418 F422 I423	D40-R420 IonicContact OD2-NH1 2.76Å; V143-R420 HydrophobicContact CG1-CG 4.24Å; F147-R420 HydrophobicContact CD2-CG 3.84Å; F147-R420 VanDerWaalsContact CE2-CD 3.4Å; F147-R420 HydrophobicContact CE2-CG 3.25Å; F147-R420 HydrophobicContact CZ-CG 3.74Å; Y152-R420 VanDerWaalsContact CD1-CZ 3.45Å; D154-R420 IonicContact OD1-CZ 3.41Å; D154-R420 IonicContact OD1-NE 2.72Å; D154-R420 PolarHBondContact OD1-NE 2.81Å; D154-R420 IonicContact OD1-NH2 3.94Å; D154-R420 IonicContact OD2-CZ 3.61Å; D154-R420 VanDerWaalsContact OD2-CZ 3.27Å; D154-R420 IonicContact OD2-NE 3.77Å; D154-R420 PolarHBondContact OD2-NE 3.09Å; D154-R420 IonicContact OD2-NH2 3.69Å; D154-R420 PolarHBondContact OD2-NH2 3.03Å; E418-R420 HydrophobicContact CG-CB 4.3Å; E418-R420 HydrophobicContact CG-CG 4.32Å; E418-R420 PolarHBondContact O-N 3.31Å; E418-R420 VanDerWaalsContact O-N 3.14Å; E418-R420 WeakPolarHBondContact OE1-CD 3.16Å; E418-R420 IonicContact OE1-CZ 3.79Å; E418-R420 IonicContact OE1-NE 2.77Å; E418-R420 IonicContact OE1-NH1 3.79Å; E418-R420 PolarHBondContact OE1-NH1 3.19Å; R420-F422 PolarHBondContact O-N 3.14Å; R420-F422 VanDerWaalsContact O-N 3.16Å; R420-I423 HydrophobicContact CB-CD1 4.24Å; R420-I423 HydrophobicContact CG-CD1 4.49Å; R420-I423 WeakPolarHBondContact O-CD1 3.35Å; R420-I423 WeakPolarHBondContact O-CG1 3.37Å; R420-I423 PolarHBondContact O-N 2.85Å
421	Y	95.4	Very high	96	Very high	38 Å²	38	14.8 Å²	14.8	15%	0.149	7%	0.072	C	C	.	.	G	3₁₀ helix	trans	-66.4	-17.3	176.9	-52.9	-22.3	0	0	0	112.1	R187 Q414 L416 E418 F419	R187-Y421 VanDerWaalsContact NH2-CE1 3.3Å; Q414-Y421 HydrophobicContact CB-CD2 4Å; Q414-Y421 HydrophobicContact CB-CE2 4.21Å; Q414-Y421 HydrophobicContact CG-CD2 3.85Å; Q414-Y421 HydrophobicContact CG-CE2 4.31Å; Q414-Y421 HydrophobicContact CG-CG 4.43Å; L416-Y421 HydrophobicContact CB-CE2 4.33Å; L416-Y421 WeakPolarHBondContact O-CE2 3.31Å; E418-Y421 HydrophobicContact CB-CD2 4.14Å; E418-Y421 HydrophobicContact CB-CE1 4.35Å; E418-Y421 HydrophobicContact CB-CE2 3.81Å; E418-Y421 PolarHBondContact O-N 3.34Å; E418-Y421 VanDerWaalsContact O-N 3.16Å; E418-Y421 PolarHBondContact OE2-OH 3.48Å; F419-Y421 PolarHBondContact O-N 3.23Å
422	F	98.1	Very high	95.8	Very high	1 Å²	1	15.2 Å²	15.2	0%	0.004	7%	0.074	C	C	.	.	G	3₁₀ helix	trans	-91.3	-7.4	-180	-57.7	-22.8	0	0	0	114	F298 F301 T411 L417 F419 R420 P425 Y426	F298-F422 HydrophobicContact CB-CD1 4.17Å; F298-F422 HydrophobicContact CB-CE1 3.99Å; F298-F422 HydrophobicContact CB-CE2 4.47Å; F298-F422 HydrophobicContact CB-CZ 4.15Å; F298-F422 HydrophobicContact CD2-CB 3.78Å; F298-F422 AromaticContact CD2-CD1 3.72Å; F298-F422 HydrophobicContact CD2-CD1 3.72Å; F298-F422 HydrophobicContact CD2-CD2 4.33Å; F298-F422 HydrophobicContact CD2-CE1 4.4Å; F298-F422 AromaticContact CD2-CG 3.69Å; F298-F422 HydrophobicContact CD2-CG 3.69Å; F298-F422 HydrophobicContact CE2-CB 4.12Å; F298-F422 HydrophobicContact CG-CD1 4.39Å; F301-F422 HydrophobicContact CB-CD2 3.96Å; F301-F422 HydrophobicContact CB-CE2 4.34Å; F301-F422 HydrophobicContact CD1-CB 3.73Å; F301-F422 AromaticContact CD1-CD2 3.91Å; F301-F422 HydrophobicContact CD1-CD2 3.91Å; F301-F422 HydrophobicContact CD1-CG 4.23Å; F301-F422 AromaticContact CD2-CD2 3.9Å; F301-F422 HydrophobicContact CD2-CD2 3.9Å; F301-F422 HydrophobicContact CE1-CB 3.46Å; F301-F422 VanDerWaalsContact CE1-CB 3.46Å; F301-F422 HydrophobicContact CE1-CD2 4.31Å; F301-F422 HydrophobicContact CE1-CG 4.39Å; F301-F422 HydrophobicContact CE2-CB 4.49Å; F301-F422 HydrophobicContact CE2-CD2 4.29Å; F301-F422 HydrophobicContact CG-CB 4.33Å; F301-F422 AromaticContact CG-CD2 3.67Å; F301-F422 HydrophobicContact CG-CD2 3.67Å; F301-F422 HydrophobicContact CG-CE2 4.47Å; F301-F422 HydrophobicContact CG-CG 4.44Å; F301-F422 HydrophobicContact CZ-CB 3.86Å; F301-F422 HydrophobicContact CZ-CD2 4.45Å; T411-F422 HydrophobicContact CG2-CD1 4.09Å; T411-F422 HydrophobicContact CG2-CE1 3.94Å; L417-F422 HydrophobicContact CD1-CE2 4.09Å; L417-F422 HydrophobicContact CD1-CZ 4.07Å; F419-F422 AromaticContact CD1-CD2 3.97Å; F419-F422 HydrophobicContact CD1-CD2 3.97Å; F419-F422 AromaticContact CD1-CE2 3.97Å; F419-F422 HydrophobicContact CD1-CE2 3.97Å; F419-F422 HydrophobicContact CE1-CE2 4.44Å; F419-F422 WeakPolarHBondContact O-CB 3.3Å; F419-F422 PolarHBondContact O-N 3.4Å; R420-F422 PolarHBondContact O-N 3.14Å; R420-F422 VanDerWaalsContact O-N 3.16Å; F422-P425 WeakPolarHBondContact O-CD 3.21Å; F422-Y426 WeakPolarHBondContact O-CB 3.36Å; F422-Y426 PolarHBondContact O-N 2.83Å
423	I	98.4	Very high	95.5	Very high	3 Å²	3	14.8 Å²	14.8	2%	0.015	7%	0.072	C	C	.	.	H	α-helix	trans	-57.4	-60.5	-175.7	-66.7	167.1	0	0	0	111.6	F141 V143 L144 D154 R420 Y426 L427	F141-I423 HydrophobicContact CE1-CG1 4.17Å; V143-I423 HydrophobicContact CB-CG1 4.31Å; V143-I423 HydrophobicContact CG1-CD1 4.04Å; V143-I423 HydrophobicContact CG1-CG1 3.99Å; L144-I423 HydrophobicContact CB-CD1 4.25Å; L144-I423 HydrophobicContact CB-CG1 4.45Å; L144-I423 HydrophobicContact CB-CG2 4Å; L144-I423 HydrophobicContact CD1-CD1 4.29Å; L144-I423 HydrophobicContact CD1-CG2 4.23Å; L144-I423 HydrophobicContact CD2-CG2 4.08Å; L144-I423 HydrophobicContact CG-CG2 4.34Å; D154-I423 HydrophobicContact CB-CD1 4.1Å; R420-I423 HydrophobicContact CB-CD1 4.24Å; R420-I423 HydrophobicContact CG-CD1 4.49Å; R420-I423 WeakPolarHBondContact O-CD1 3.35Å; R420-I423 WeakPolarHBondContact O-CG1 3.37Å; R420-I423 PolarHBondContact O-N 2.85Å; I423-Y426 PolarHBondContact O-N 2.91Å; I423-L427 HydrophobicContact CG2-CD1 3.95Å; I423-L427 WeakPolarHBondContact O-CG 3.5Å; I423-L427 PolarHBondContact O-N 3.44Å
424	I	98.3	Very high	95.1	Very high	15 Å²	15	15.9 Å²	15.9	8%	0.077	8%	0.078	C	C	.	.	H	α-helix	trans	-63.4	-49.4	-176.5	-59	173.4	0	0	0	111.7	I161 N190 W193 Y426 L427 M428	I161-I424 HydrophobicContact CB-CD1 4.49Å; I161-I424 HydrophobicContact CG1-CD1 4.13Å; I161-I424 HydrophobicContact CG2-CG2 3.87Å; N190-I424 WeakPolarHBondContact OD1-CD1 3.5Å; W193-I424 HydrophobicContact CD2-CB 4.39Å; W193-I424 HydrophobicContact CD2-CG2 3.38Å; W193-I424 HydrophobicContact CE3-CG2 3.95Å; W193-I424 HydrophobicContact CG-CG2 3.62Å; W193-I424 HydrophobicContact CH2-CG2 4.5Å; W193-I424 HydrophobicContact CZ2-CB 4.36Å; W193-I424 HydrophobicContact CZ2-CG2 3.99Å; W193-I424 HydrophobicContact CZ3-CG2 4.46Å; I424-Y426 VanDerWaalsContact C-N 3.27Å; I424-Y426 PolarHBondContact O-N 2.9Å; I424-L427 PolarHBondContact O-N 3.41Å; I424-M428 HydrophobicContact CG2-CE 4.43Å; I424-M428 HydrophobicContact CG2-CG 4.1Å; I424-M428 WeakPolarHBondContact O-CB 3.48Å; I424-M428 WeakPolarHBondContact O-CG 3.42Å; I424-M428 PolarHBondContact O-N 2.8Å
425	P	98.2	Very high	94.9	Very high	1 Å²	1	14.6 Å²	14.6	1%	0.006	7%	0.073	C	C	.	.	H	α-helix	trans	-60	-39	177.8	9.1	-14.8	0	0	0	112.2	W193 F298 Y403 L407 F422 M428 Y429	W193-P425 VanDerWaalsContact CH2-CA 3.42Å; W193-P425 HydrophobicContact CH2-CB 3.61Å; W193-P425 HydrophobicContact CH2-CG 4.31Å; W193-P425 HydrophobicContact CZ2-CB 3.49Å; W193-P425 VanDerWaalsContact CZ2-CB 3.49Å; W193-P425 VanDerWaalsContact CZ2-CD 3.44Å; W193-P425 HydrophobicContact CZ2-CG 3.67Å; F298-P425 HydrophobicContact CE2-CB 3.69Å; F298-P425 HydrophobicContact CE2-CG 3.99Å; F298-P425 HydrophobicContact CZ-CB 3.7Å; F298-P425 HydrophobicContact CZ-CG 4.48Å; Y403-P425 PolarHBondContact OH-O 2.91Å; L407-P425 HydrophobicContact CD1-CB 3.74Å; L407-P425 HydrophobicContact CD1-CG 4.32Å; F422-P425 WeakPolarHBondContact O-CD 3.21Å; P425-M428 PolarHBondContact O-N 3.18Å; P425-Y429 WeakPolarHBondContact O-CB 3.48Å; P425-Y429 PolarHBondContact O-N 2.95Å
426	Y	98.4	Very high	94.9	Very high	0 Å²	0	12.6 Å²	12.6	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-62.7	-47.3	176.2	-179.7	-95.6	0	0	0	112.8	L138 F141 F301 T302 F305 F422 I423 I424 M428 Y429 R430 Y448	L138-Y426 HydrophobicContact CD2-CE1 4.49Å; F141-Y426 HydrophobicContact CD1-CD1 4.33Å; F141-Y426 AromaticContact CD2-CD1 3.89Å; F141-Y426 HydrophobicContact CD2-CD1 3.89Å; F141-Y426 AromaticContact CD2-CE1 3.69Å; F141-Y426 HydrophobicContact CD2-CE1 3.69Å; F141-Y426 HydrophobicContact CE1-CD1 4.01Å; F141-Y426 AromaticContact CE2-CD1 3.55Å; F141-Y426 HydrophobicContact CE2-CD1 3.55Å; F141-Y426 AromaticContact CE2-CE1 3.57Å; F141-Y426 HydrophobicContact CE2-CE1 3.57Å; F141-Y426 HydrophobicContact CE2-CG 4.25Å; F141-Y426 HydrophobicContact CG-CD1 4.27Å; F141-Y426 HydrophobicContact CG-CE1 4.35Å; F141-Y426 AromaticContact CZ-CD1 3.59Å; F141-Y426 HydrophobicContact CZ-CD1 3.59Å; F141-Y426 HydrophobicContact CZ-CE1 4.11Å; F141-Y426 HydrophobicContact CZ-CG 4.02Å; F301-Y426 HydrophobicContact CD1-CD2 4.42Å; F301-Y426 HydrophobicContact CE1-CD2 4.25Å; F301-Y426 HydrophobicContact CE1-CG 4.19Å; T302-Y426 HydrophobicContact CG2-CD2 3.97Å; T302-Y426 HydrophobicContact CG2-CE2 3.99Å; F305-Y426 HydrophobicContact CB-CE2 3.81Å; F305-Y426 PolarHBondContact O-OH 2.7Å; F422-Y426 WeakPolarHBondContact O-CB 3.36Å; F422-Y426 PolarHBondContact O-N 2.83Å; I423-Y426 PolarHBondContact O-N 2.91Å; I424-Y426 VanDerWaalsContact C-N 3.27Å; I424-Y426 PolarHBondContact O-N 2.9Å; Y426-M428 PolarHBondContact O-N 3.29Å; Y426-Y429 WeakPolarHBondContact O-CB 3.37Å; Y426-Y429 PolarHBondContact O-N 2.86Å; Y426-R430 HydrophobicContact CD1-CG 4.32Å; Y426-R430 HydrophobicContact CE1-CG 3.6Å; Y426-R430 HydrophobicContact CE2-CG 4.06Å; Y426-R430 VanDerWaalsContact CZ-CG 3.42Å; Y426-R430 PolarHBondContact O-N 2.61Å; Y426-R430 WeakPolarHBondContact OH-CD 3.3Å; Y426-R430 VanDerWaalsContact OH-CG 3.3Å; Y426-R430 WeakPolarHBondContact OH-CG 3.4Å; Y426-Y448 VanDerWaalsContact CE1-OH 3.24Å; Y426-Y448 WeakPolarHBondContact CE1-OH 3.28Å; Y426-Y448 VanDerWaalsContact CZ-OH 3.22Å; Y426-Y448 PolarHBondContact OH-OH 3.08Å
427	L	98.4	Very high	94.8	Very high	1 Å²	1	14.4 Å²	14.4	1%	0.005	8%	0.079	C	C	.	.	H	α-helix	trans	-62.6	-43.4	177.8	-70.4	177.1	0	0	0	111.3	L138 F141 L144 T158 I423 I424 Y429 R430 L431	L138-L427 HydrophobicContact CB-CD2 4.24Å; L138-L427 HydrophobicContact CD2-CD2 4.39Å; F141-L427 HydrophobicContact CB-CD2 4.44Å; L144-L427 HydrophobicContact CD2-CD1 4.05Å; T158-L427 HydrophobicContact CG2-CD1 3.5Å; I423-L427 HydrophobicContact CG2-CD1 3.95Å; I423-L427 WeakPolarHBondContact O-CG 3.5Å; I423-L427 PolarHBondContact O-N 3.44Å; I424-L427 PolarHBondContact O-N 3.41Å; L427-Y429 PolarHBondContact O-N 3.21Å; L427-R430 PolarHBondContact O-N 3.41Å; L427-L431 WeakPolarHBondContact O-CB 3.49Å; L427-L431 VanDerWaalsContact O-CG 3.28Å; L427-L431 WeakPolarHBondContact O-CG 3.11Å; L427-L431 PolarHBondContact O-N 2.88Å
428	M	97.4	Very high	94.7	Very high	0 Å²	0	17.8 Å²	17.8	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-62.5	-42.6	175.8	-70.8	-61.4	170.6	0	0	111.5	I161 L162 Y165 W193 F196 Y403 I424 P425 Y426 L431 H432	I161-M428 HydrophobicContact CG2-CE 3.47Å; I161-M428 VanDerWaalsContact CG2-CE 3.47Å; L162-M428 HydrophobicContact CD2-CE 4.02Å; Y165-M428 HydrophobicContact CD1-CE 4.23Å; Y165-M428 HydrophobicContact CD1-SD 3.99Å; Y165-M428 HydrophobicContact CE1-SD 4.35Å; Y165-M428 HydrophobicContact CG-CE 4.28Å; Y165-M428 HydrophobicContact CG-SD 4.41Å; W193-M428 HydrophobicContact CE3-CG 3.96Å; W193-M428 HydrophobicContact CH2-CB 4.41Å; W193-M428 HydrophobicContact CH2-CG 4.42Å; W193-M428 HydrophobicContact CZ3-CB 3.97Å; W193-M428 HydrophobicContact CZ3-CG 3.73Å; F196-M428 HydrophobicContact CE1-CG 4.45Å; F196-M428 HydrophobicContact CE1-SD 3.94Å; Y403-M428 HydrophobicContact CD2-CB 4.41Å; Y403-M428 HydrophobicContact CE2-CB 3.82Å; I424-M428 HydrophobicContact CG2-CE 4.43Å; I424-M428 HydrophobicContact CG2-CG 4.1Å; I424-M428 WeakPolarHBondContact O-CB 3.48Å; I424-M428 WeakPolarHBondContact O-CG 3.42Å; I424-M428 PolarHBondContact O-N 2.8Å; P425-M428 PolarHBondContact O-N 3.18Å; Y426-M428 PolarHBondContact O-N 3.29Å; M428-L431 HydrophobicContact SD-CD1 4.31Å; M428-H432 PolarHBondContact O-N 2.9Å; M428-H432 PolarHBondContact O-ND1 3.25Å
429	Y	96.5	Very high	94.7	Very high	3 Å²	3	21.4 Å²	21.4	1%	0.012	12%	0.123	C	C	.	.	H	α-helix	trans	-57	-52	172.1	168.8	-104	0	0	0	111.3	T302 F388 T391 L392 P425 Y426 L427 L431 H432 M433	T302-Y429 HydrophobicContact CG2-CD1 3.41Å; T302-Y429 VanDerWaalsContact CG2-CD1 3.41Å; T302-Y429 HydrophobicContact CG2-CE1 3.27Å; T302-Y429 HydrophobicContact CG2-CG 4.16Å; F388-Y429 AromaticContact CD2-CD2 3.86Å; F388-Y429 HydrophobicContact CD2-CD2 3.86Å; F388-Y429 HydrophobicContact CD2-CE1 4.49Å; F388-Y429 AromaticContact CD2-CE2 3.55Å; F388-Y429 HydrophobicContact CD2-CE2 3.55Å; F388-Y429 HydrophobicContact CD2-CG 4.43Å; F388-Y429 AromaticContact CD2-CZ 3.9Å; F388-Y429 HydrophobicContact CE1-CD2 4.31Å; F388-Y429 HydrophobicContact CE1-CE2 4.49Å; F388-Y429 HydrophobicContact CE2-CD1 4.2Å; F388-Y429 AromaticContact CE2-CD2 3.18Å; F388-Y429 HydrophobicContact CE2-CD2 3.18Å; F388-Y429 HydrophobicContact CE2-CE1 4.38Å; F388-Y429 AromaticContact CE2-CE2 3.41Å; F388-Y429 HydrophobicContact CE2-CE2 3.41Å; F388-Y429 VanDerWaalsContact CE2-CE2 3.41Å; F388-Y429 AromaticContact CE2-CG 3.61Å; F388-Y429 HydrophobicContact CE2-CG 3.61Å; F388-Y429 HydrophobicContact CG-CE2 4.15Å; F388-Y429 AromaticContact CZ-CD2 3.42Å; F388-Y429 HydrophobicContact CZ-CD2 3.42Å; F388-Y429 VanDerWaalsContact CZ-CD2 3.42Å; F388-Y429 AromaticContact CZ-CE2 3.88Å; F388-Y429 HydrophobicContact CZ-CE2 3.88Å; F388-Y429 HydrophobicContact CZ-CG 4.08Å; T391-Y429 WeakPolarHBondContact CB-OH 3.42Å; T391-Y429 HydrophobicContact CG2-CE2 3.91Å; T391-Y429 WeakPolarHBondContact CG2-OH 3.27Å; T391-Y429 PolarHBondContact OG1-OH 2.79Å; L392-Y429 HydrophobicContact CD2-CD2 4.22Å; L392-Y429 HydrophobicContact CD2-CE2 4.49Å; P425-Y429 WeakPolarHBondContact O-CB 3.48Å; P425-Y429 PolarHBondContact O-N 2.95Å; Y426-Y429 WeakPolarHBondContact O-CB 3.37Å; Y426-Y429 PolarHBondContact O-N 2.86Å; L427-Y429 PolarHBondContact O-N 3.21Å; Y429-L431 PolarHBondContact O-N 3.32Å; Y429-H432 CarbonylContact O-C 3.55Å; Y429-H432 PolarHBondContact O-N 3.1Å; Y429-H432 VanDerWaalsContact O-N 3.11Å; Y429-M433 HydrophobicContact CD1-CG 4.29Å; Y429-M433 HydrophobicContact CD1-SD 3.93Å; Y429-M433 HydrophobicContact CE1-CE 4.46Å; Y429-M433 HydrophobicContact CE1-CG 3.97Å; Y429-M433 HydrophobicContact CE1-SD 3.21Å; Y429-M433 WeakPolarHBondContact CE1-SD 3.38Å; Y429-M433 HydrophobicContact CE2-CG 4.23Å; Y429-M433 HydrophobicContact CE2-SD 4.33Å; Y429-M433 WeakPolarHBondContact O-CG 3.3Å; Y429-M433 PolarHBondContact O-N 3.36Å
430	R	95.8	Very high	94.6	Very high	2 Å²	2	24.1 Å²	24.1	1%	0.008	13%	0.133	C	C	.	.	H	α-helix	trans	-64.5	-39.5	-177.2	-76.8	-61	-69.5	90.4	4.2	113.5	L138 Y426 L427 H432 M433 E444	L138-R430 HydrophobicContact CD1-CB 3.98Å; L138-R430 HydrophobicContact CD2-CB 3.64Å; L138-R430 HydrophobicContact CD2-CG 3.83Å; L138-R430 HydrophobicContact CG-CB 4.48Å; Y426-R430 HydrophobicContact CD1-CG 4.32Å; Y426-R430 HydrophobicContact CE1-CG 3.6Å; Y426-R430 HydrophobicContact CE2-CG 4.06Å; Y426-R430 VanDerWaalsContact CZ-CG 3.42Å; Y426-R430 PolarHBondContact O-N 2.61Å; Y426-R430 WeakPolarHBondContact OH-CD 3.3Å; Y426-R430 VanDerWaalsContact OH-CG 3.3Å; Y426-R430 WeakPolarHBondContact OH-CG 3.4Å; L427-R430 PolarHBondContact O-N 3.41Å; R430-H432 PolarHBondContact O-N 2.81Å; R430-M433 PolarHBondContact O-N 3.37Å; R430-E444 IonicContact CZ-OE1 3.22Å; R430-E444 IonicContact CZ-OE2 3.4Å; R430-E444 IonicContact NE-OE1 3.55Å; R430-E444 PolarHBondContact NE-OE1 2.88Å; R430-E444 IonicContact NE-OE2 3.26Å; R430-E444 IonicContact NH2-OE1 3.28Å; R430-E444 PolarHBondContact NH2-OE1 3.49Å; R430-E444 VanDerWaalsContact NH2-OE1 3.17Å; R430-E444 IonicContact NH2-OE2 2.72Å; R430-E444 PolarHBondContact NH2-OE2 2.82Å
431	L	94.8	Very high	94.5	Very high	1 Å²	1	23.1 Å²	23.1	1%	0.005	13%	0.129	C	C	.	.	H	α-helix	trans	-58.6	-36.8	174.1	-75.3	171.3	0	0	0	111.7	L112 L115 I116 L119 H120 L138 L162 L427 M428 Y429	L112-L431 HydrophobicContact CD2-CD1 4.33Å; L112-L431 HydrophobicContact CD2-CD2 4.03Å; L112-L431 HydrophobicContact CD2-CG 4.39Å; L115-L431 HydrophobicContact CB-CD2 4.02Å; L115-L431 HydrophobicContact CD1-CD1 3.92Å; I116-L431 HydrophobicContact CD1-CD2 4.4Å; I116-L431 HydrophobicContact CG1-CD2 3.67Å; L119-L431 HydrophobicContact CD1-CB 3.99Å; H120-L431 PolarHBondContact NE2-O 2.99Å; L138-L431 HydrophobicContact CD1-CD2 4.36Å; L162-L431 HydrophobicContact CD2-CD1 3.84Å; L427-L431 WeakPolarHBondContact O-CB 3.49Å; L427-L431 VanDerWaalsContact O-CG 3.28Å; L427-L431 WeakPolarHBondContact O-CG 3.11Å; L427-L431 PolarHBondContact O-N 2.88Å; M428-L431 HydrophobicContact SD-CD1 4.31Å; Y429-L431 PolarHBondContact O-N 3.32Å
432	H	92.1	Very high	94.6	Very high	10 Å²	10	27 Å²	27	5%	0.046	15%	0.147	C	C	.	.	H	α-helix	trans	-84.9	-13.6	179.8	-69.2	90	0	0	0	114	Y165 F196 R395 M428 Y429 R430	Y165-H432 AromaticContact CE1-CE1 3.66Å; Y165-H432 AromaticContact CZ-CE1 3.61Å; Y165-H432 AromaticContact CZ-NE2 3.62Å; Y165-H432 PolarHBondContact OH-CE1 2.87Å; Y165-H432 PolarHBondContact OH-NE2 3.37Å; F196-H432 AromaticContact CZ-CE1 3.93Å; R395-H432 HydrophobicContact CG-CB 4.39Å; R395-H432 PolarHBondContact NE-O 3.38Å; R395-H432 VanDerWaalsContact NH2-CA 3.33Å; R395-H432 PolarHBondContact NH2-O 3.47Å; M428-H432 PolarHBondContact O-N 2.9Å; M428-H432 PolarHBondContact O-ND1 3.25Å; Y429-H432 CarbonylContact O-C 3.55Å; Y429-H432 PolarHBondContact O-N 3.1Å; Y429-H432 VanDerWaalsContact O-N 3.11Å; R430-H432 PolarHBondContact O-N 2.81Å
433	M	90	Very high	94.6	Very high	5 Å²	5	28 Å²	28	3%	0.025	16%	0.157	C	C	.	.	S	Bend	trans	-67.5	144.6	172.4	-66.1	-170.9	64.9	0	0	111.5	H120 V309 T391 Y429 R430 L435	H120-M433 PolarHBondContact CE1-O 3.26Å; H120-M433 PolarHBondContact NE2-O 3.33Å; V309-M433 HydrophobicContact CG1-CE 3.68Å; T391-M433 HydrophobicContact CG2-CB 4.24Å; T391-M433 HydrophobicContact CG2-CE 3.46Å; T391-M433 VanDerWaalsContact CG2-CE 3.46Å; T391-M433 HydrophobicContact CG2-CG 3.46Å; T391-M433 VanDerWaalsContact CG2-CG 3.46Å; T391-M433 HydrophobicContact CG2-SD 3.88Å; Y429-M433 HydrophobicContact CD1-CG 4.29Å; Y429-M433 HydrophobicContact CD1-SD 3.93Å; Y429-M433 HydrophobicContact CE1-CE 4.46Å; Y429-M433 HydrophobicContact CE1-CG 3.97Å; Y429-M433 HydrophobicContact CE1-SD 3.21Å; Y429-M433 WeakPolarHBondContact CE1-SD 3.38Å; Y429-M433 HydrophobicContact CE2-CG 4.23Å; Y429-M433 HydrophobicContact CE2-SD 4.33Å; Y429-M433 WeakPolarHBondContact O-CG 3.3Å; Y429-M433 PolarHBondContact O-N 3.36Å; R430-M433 PolarHBondContact O-N 3.37Å; M433-L435 PolarHBondContact O-N 2.91Å
434	P	88.3	Confident	94.5	Very high	65 Å²	65	27.8 Å²	27.8	42%	0.422	16%	0.156	S	C	.	.	P	Polyproline II helix	trans	-55.3	136.9	165	-22	33.5	0	0	0	110.1	S394 S436	S394-P434 WeakPolarHBondContact OG-CD 3.46Å; S394-P434 WeakPolarHBondContact OG-CG 3.4Å; P434-S436 PolarHBondContact O-N 2.88Å
435	L	89.1	Confident	94.4	Very high	13 Å²	13	29.9 Å²	29.9	7%	0.068	17%	0.165	C	C	.	.	P	Polyproline II helix	trans	-56.1	135.2	174.3	-68.9	175.6	0	0	0	109.1	I116 H120 L127 R130 R131 C134 M433	I116-L435 HydrophobicContact CG2-CD1 4.44Å; I116-L435 HydrophobicContact CG2-CD2 4.35Å; H120-L435 HydrophobicContact CB-CD1 3.8Å; H120-L435 HydrophobicContact CB-CG 4.31Å; L127-L435 HydrophobicContact CD1-CD1 3.76Å; L127-L435 HydrophobicContact CD2-CD1 4.44Å; L127-L435 HydrophobicContact CG-CD1 3.89Å; R130-L435 HydrophobicContact CB-CD1 4.42Å; R130-L435 VanDerWaalsContact NH2-C 3.3Å; R130-L435 PolarHBondContact NH2-O 3.42Å; R131-L435 HydrophobicContact CG-CD1 3.98Å; C134-L435 HydrophobicContact CB-CD2 3.87Å; M433-L435 PolarHBondContact O-N 2.91Å
436	S	90.3	Very high	94.4	Very high	14 Å²	14	33.9 Å²	33.9	10%	0.098	19%	0.186	C	C	.	.	P	Polyproline II helix	trans	-87.8	167.7	176.2	-84.8	0	0	0	0	111.9	R130 V309 P434 L441	R130-S436 PolarHBondContact NE-O 2.81Å; R130-S436 PolarHBondContact NH2-O 3.49Å; V309-S436 WeakPolarHBondContact CG1-OG 2.98Å; P434-S436 PolarHBondContact O-N 2.88Å; S436-L441 WeakPolarHBondContact O-CD1 3.49Å
437	P	91.3	Very high	94.4	Very high	67 Å²	67	35.5 Å²	35.5	44%	0.435	19%	0.194	S	C	.	.	P	Polyproline II helix	trans	-55.8	154.6	169.6	-24	34.6	0	0	0	111.9	S439 R440 L441	P437-S439 VanDerWaalsContact C-N 3.28Å; P437-S439 PolarHBondContact O-N 2.98Å; P437-R440 PolarHBondContact O-N 3.25Å; P437-R440 VanDerWaalsContact O-N 3.1Å; P437-L441 PolarHBondContact O-N 2.85Å; P437-L441 VanDerWaalsContact O-N 3.16Å
438	L	91.9	Very high	94.4	Very high	77 Å²	77	35.4 Å²	35.4	40%	0.403	19%	0.194	S	C	.	.	H	α-helix	trans	-55.4	-39.7	-176.5	-75.3	171.3	0	0	0	113.2	F129 R130 L133 R440 L441 F442	F129-L438 HydrophobicContact CB-CD1 4.27Å; F129-L438 HydrophobicContact CB-CD2 3.86Å; R130-L438 HydrophobicContact CB-CD2 4.41Å; R130-L438 HydrophobicContact CG-CD2 3.67Å; R130-L438 HydrophobicContact CG-CG 3.87Å; L133-L438 HydrophobicContact CD2-CD2 4.2Å; L438-R440 VanDerWaalsContact C-N 3.31Å; L438-R440 PolarHBondContact O-N 3.44Å; L438-L441 PolarHBondContact O-N 2.96Å; L438-F442 WeakPolarHBondContact O-CB 3.07Å; L438-F442 PolarHBondContact O-N 3.36Å
439	S	93.4	Very high	94.5	Very high	90 Å²	90	37.8 Å²	37.8	63%	0.629	21%	0.208	S	C	*	.	H	α-helix	trans	-58.5	-41	178.7	53.5	0	0	0	0	113	P437 G443	P437-S439 VanDerWaalsContact C-N 3.28Å; P437-S439 PolarHBondContact O-N 2.98Å; S439-G443 PolarHBondContact O-N 3.19Å
440	R	94.4	Very high	94.6	Very high	80 Å²	80	42.3 Å²	42.3	30%	0.302	23%	0.232	S	C	.	.	H	α-helix	trans	-73.1	-39.3	178.1	-67.4	-168.3	-174.3	-177.7	3.7	112.3	P308 V309 P437 L438 F442 G443 E444	P308-R440 WeakPolarHBondContact CB-O 3.49Å; P308-R440 WeakPolarHBondContact O-CB 3.41Å; P308-R440 VanDerWaalsContact O-CD 3.3Å; P308-R440 WeakPolarHBondContact O-CD 3.22Å; P308-R440 VanDerWaalsContact O-CG 3.26Å; P308-R440 WeakPolarHBondContact O-CG 3.3Å; V309-R440 PolarHBondContact O-NH1 3.24Å; P437-R440 PolarHBondContact O-N 3.25Å; P437-R440 VanDerWaalsContact O-N 3.1Å; L438-R440 VanDerWaalsContact C-N 3.31Å; L438-R440 PolarHBondContact O-N 3.44Å; R440-F442 VanDerWaalsContact C-N 3.31Å; R440-G443 PolarHBondContact O-N 2.79Å; R440-E444 PolarHBondContact O-N 3.42Å
441	L	95.1	Very high	94.7	Very high	0 Å²	0	43.2 Å²	43.2	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-65.5	-37	174.7	-68.5	174.8	0	0	0	111.5	R130 L133 C134 V309 S436 P437 L438 E444 F445	R130-L441 HydrophobicContact CB-CD1 3.81Å; R130-L441 HydrophobicContact CG-CD1 4.11Å; R130-L441 WeakPolarHBondContact O-CD1 3.42Å; L133-L441 HydrophobicContact CD2-CB 3.72Å; L133-L441 HydrophobicContact CG-CB 3.96Å; C134-L441 HydrophobicContact CB-CD1 4.47Å; C134-L441 HydrophobicContact CB-CD2 4.17Å; V309-L441 HydrophobicContact CG2-CD2 4.44Å; S436-L441 WeakPolarHBondContact O-CD1 3.49Å; P437-L441 PolarHBondContact O-N 2.85Å; P437-L441 VanDerWaalsContact O-N 3.16Å; L438-L441 PolarHBondContact O-N 2.96Å; L441-E444 WeakPolarHBondContact O-CB 3.49Å; L441-E444 PolarHBondContact O-N 3.28Å; L441-F445 PolarHBondContact O-N 3.01Å
442	F	96.2	Very high	94.9	Very high	118 Å²	118	43.6 Å²	43.6	52%	0.518	24%	0.24	S	C	.	.	H	α-helix	trans	-66.7	-41.4	173.6	-175.7	-100.3	0	0	0	111.3	L133 L438 R440 E444 F445 L446	L133-F442 HydrophobicContact CD2-CB 4.08Å; L438-F442 WeakPolarHBondContact O-CB 3.07Å; L438-F442 PolarHBondContact O-N 3.36Å; R440-F442 VanDerWaalsContact C-N 3.31Å; F442-E444 VanDerWaalsContact C-N 3.32Å; F442-E444 PolarHBondContact O-N 2.99Å; F442-F445 WeakPolarHBondContact O-CB 3.42Å; F442-F445 PolarHBondContact O-N 3.03Å; F442-L446 WeakPolarHBondContact O-CB 3.36Å; F442-L446 PolarHBondContact O-N 3.05Å
443	G	97.4	Very high	95.2	Very high	22 Å²	22	47.7 Å²	47.7	23%	0.227	27%	0.265	C	S	.	.	H	α-helix	trans	-59.1	-40.7	171.4	0	0	0	0	0	112.9	P308 S439 R440 L446 L447	P308-G443 VanDerWaalsContact CG-C 3.49Å; S439-G443 PolarHBondContact O-N 3.19Å; R440-G443 PolarHBondContact O-N 2.79Å; G443-L446 PolarHBondContact O-N 2.84Å; G443-L447 WeakPolarHBondContact O-CB 3.47Å; G443-L447 PolarHBondContact O-N 3.17Å
444	E	97.1	Very high	95.6	Very high	0 Å²	0	49.7 Å²	49.7	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-63.9	-46.6	174.4	-176.4	178.4	-117.7	0	0	111.5	P308 V309 R430 R440 L441 F442 L446 L447 Y448	P308-E444 HydrophobicContact CB-CB 4.39Å; P308-E444 HydrophobicContact CG-CB 4.45Å; V309-E444 HydrophobicContact CG2-CB 3.99Å; V309-E444 HydrophobicContact CG2-CG 4.36Å; R430-E444 IonicContact CZ-OE1 3.22Å; R430-E444 IonicContact CZ-OE2 3.4Å; R430-E444 IonicContact NE-OE1 3.55Å; R430-E444 PolarHBondContact NE-OE1 2.88Å; R430-E444 IonicContact NE-OE2 3.26Å; R430-E444 IonicContact NH2-OE1 3.28Å; R430-E444 PolarHBondContact NH2-OE1 3.49Å; R430-E444 VanDerWaalsContact NH2-OE1 3.17Å; R430-E444 IonicContact NH2-OE2 2.72Å; R430-E444 PolarHBondContact NH2-OE2 2.82Å; R440-E444 PolarHBondContact O-N 3.42Å; L441-E444 WeakPolarHBondContact O-CB 3.49Å; L441-E444 PolarHBondContact O-N 3.28Å; F442-E444 VanDerWaalsContact C-N 3.32Å; F442-E444 PolarHBondContact O-N 2.99Å; E444-L446 VanDerWaalsContact C-N 3.31Å; E444-L446 PolarHBondContact O-N 2.95Å; E444-L447 PolarHBondContact O-N 2.88Å; E444-Y448 HydrophobicContact CG-CE1 4.1Å; E444-Y448 HydrophobicContact CG-CE2 4.17Å; E444-Y448 WeakPolarHBondContact O-CD1 3.31Å; E444-Y448 PolarHBondContact O-N 3.25Å
445	F	97.4	Very high	96	Very high	59 Å²	59	47 Å²	47	26%	0.259	27%	0.265	S	S	.	.	H	α-helix	trans	-57.8	-44	175	178.4	-111.6	0	0	0	112	L133 V136 S137 L441 F442 Y448 T449	L133-F445 HydrophobicContact CD1-CB 4.09Å; L133-F445 HydrophobicContact CD1-CG 4.24Å; V136-F445 HydrophobicContact CG1-CD2 3.87Å; V136-F445 HydrophobicContact CG1-CE2 3.49Å; V136-F445 VanDerWaalsContact CG1-CE2 3.49Å; V136-F445 HydrophobicContact CG1-CZ 4.29Å; S137-F445 WeakPolarHBondContact OG-CA 3.49Å; S137-F445 WeakPolarHBondContact OG-CB 3.41Å; L441-F445 PolarHBondContact O-N 3.01Å; F442-F445 WeakPolarHBondContact O-CB 3.42Å; F442-F445 PolarHBondContact O-N 3.03Å; F445-Y448 PolarHBondContact O-N 2.99Å; F445-T449 WeakPolarHBondContact O-CB 3.37Å; F445-T449 PolarHBondContact O-N 3.38Å; F445-T449 PolarHBondContact O-OG1 2.89Å
446	L	98.2	Very high	96.4	Very high	85 Å²	85	47 Å²	47	45%	0.445	27%	0.265	S	S	.	.	H	α-helix	trans	-65.6	-45.4	178.4	-178.6	61.8	0	0	0	111.4	F442 G443 E444 Y448 T449 I450	F442-L446 WeakPolarHBondContact O-CB 3.36Å; F442-L446 PolarHBondContact O-N 3.05Å; G443-L446 PolarHBondContact O-N 2.84Å; E444-L446 VanDerWaalsContact C-N 3.31Å; E444-L446 PolarHBondContact O-N 2.95Å; L446-Y448 VanDerWaalsContact C-N 3.28Å; L446-Y448 PolarHBondContact O-N 2.82Å; L446-T449 PolarHBondContact O-N 2.69Å; L446-I450 HydrophobicContact CD1-CD1 4.07Å; L446-I450 HydrophobicContact CD1-CG1 4.26Å; L446-I450 HydrophobicContact CG-CD1 3.87Å; L446-I450 HydrophobicContact CG-CG1 4.48Å; L446-I450 VanDerWaalsContact O-CG1 3.27Å; L446-I450 WeakPolarHBondContact O-CG1 3.3Å; L446-I450 PolarHBondContact O-N 3.18Å
447	L	98.3	Very high	96.8	Very high	33 Å²	33	52.4 Å²	52.4	17%	0.173	28%	0.284	C	S	.	.	H	α-helix	trans	-54.5	-47.7	174.3	173.3	62.8	0	0	0	110.6	F304 P308 G443 E444 I450 V451	F304-L447 HydrophobicContact CZ-CD1 4.36Å; F304-L447 WeakPolarHBondContact O-CD2 3.36Å; P308-L447 HydrophobicContact CG-CB 4.33Å; P308-L447 HydrophobicContact CG-CD2 4.17Å; G443-L447 WeakPolarHBondContact O-CB 3.47Å; G443-L447 PolarHBondContact O-N 3.17Å; E444-L447 PolarHBondContact O-N 2.88Å; L447-I450 PolarHBondContact O-N 2.81Å; L447-V451 HydrophobicContact CD1-CG2 4.19Å; L447-V451 VanDerWaalsContact O-CG2 3.3Å; L447-V451 WeakPolarHBondContact O-CG2 3.25Å; L447-V451 PolarHBondContact O-N 3.3Å
448	Y	98.4	Very high	97	Very high	0 Å²	0	52 Å²	52	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-66.4	-41.7	-179.8	-72	4.5	0	0	0	112.5	S137 F141 P142 F305 Y426 E444 F445 L446 I450 V451 N452	S137-Y448 WeakPolarHBondContact O-CD2 3.18Å; S137-Y448 WeakPolarHBondContact O-CE2 3.21Å; F141-Y448 HydrophobicContact CB-CE2 4.31Å; F141-Y448 HydrophobicContact CD2-CE1 4.36Å; F141-Y448 HydrophobicContact CD2-CE2 4.01Å; F141-Y448 AromaticContact CD2-CZ 3.8Å; P142-Y448 HydrophobicContact CG-CD1 3.88Å; P142-Y448 HydrophobicContact CG-CG 3.86Å; F305-Y448 HydrophobicContact CB-CE1 4.04Å; F305-Y448 HydrophobicContact CD1-CD1 4.2Å; F305-Y448 AromaticContact CD1-CE1 3.77Å; F305-Y448 HydrophobicContact CD1-CE1 3.77Å; F305-Y448 HydrophobicContact CG-CE1 4.39Å; F305-Y448 VanDerWaalsContact O-CE1 3.24Å; F305-Y448 WeakPolarHBondContact O-CE1 3.36Å; F305-Y448 PolarHBondContact O-OH 3.31Å; Y426-Y448 VanDerWaalsContact CE1-OH 3.24Å; Y426-Y448 WeakPolarHBondContact CE1-OH 3.28Å; Y426-Y448 VanDerWaalsContact CZ-OH 3.22Å; Y426-Y448 PolarHBondContact OH-OH 3.08Å; E444-Y448 HydrophobicContact CG-CE1 4.1Å; E444-Y448 HydrophobicContact CG-CE2 4.17Å; E444-Y448 WeakPolarHBondContact O-CD1 3.31Å; E444-Y448 PolarHBondContact O-N 3.25Å; F445-Y448 PolarHBondContact O-N 2.99Å; L446-Y448 VanDerWaalsContact C-N 3.28Å; L446-Y448 PolarHBondContact O-N 2.82Å; Y448-I450 VanDerWaalsContact C-N 3.33Å; Y448-I450 PolarHBondContact O-N 3.21Å; Y448-V451 PolarHBondContact O-N 2.8Å; Y448-N452 VanDerWaalsContact O-CB 3.3Å; Y448-N452 WeakPolarHBondContact O-CB 3.46Å; Y448-N452 PolarHBondContact O-N 3Å; Y448-N452 PolarHBondContact O-ND2 2.87Å; Y448-N452 VanDerWaalsContact O-ND2 3.1Å
449	T	98.3	Very high	97.3	Very high	49 Å²	49	48.3 Å²	48.3	30%	0.301	26%	0.258	S	S	.	.	H	α-helix	trans	-60.1	-45.4	176.4	-58.7	0	0	0	0	110.6	F445 L446 N452 V453	F445-T449 WeakPolarHBondContact O-CB 3.37Å; F445-T449 PolarHBondContact O-N 3.38Å; F445-T449 PolarHBondContact O-OG1 2.89Å; L446-T449 PolarHBondContact O-N 2.69Å; T449-N452 PolarHBondContact O-N 3.4Å; T449-V453 HydrophobicContact CG2-CG2 4.38Å; T449-V453 WeakPolarHBondContact O-CB 3.47Å; T449-V453 VanDerWaalsContact O-CG2 3.25Å; T449-V453 WeakPolarHBondContact O-CG2 3.33Å; T449-V453 PolarHBondContact O-N 3.39Å
450	I	98.6	Very high	97.4	Very high	99 Å²	99	45.8 Å²	45.8	51%	0.508	24%	0.237	S	C	.	.	H	α-helix	trans	-61.1	-47.6	177.2	-69.4	166.2	0	0	0	110.9	L446 L447 Y448 V453 A454	L446-I450 HydrophobicContact CD1-CD1 4.07Å; L446-I450 HydrophobicContact CD1-CG1 4.26Å; L446-I450 HydrophobicContact CG-CD1 3.87Å; L446-I450 HydrophobicContact CG-CG1 4.48Å; L446-I450 VanDerWaalsContact O-CG1 3.27Å; L446-I450 WeakPolarHBondContact O-CG1 3.3Å; L446-I450 PolarHBondContact O-N 3.18Å; L447-I450 PolarHBondContact O-N 2.81Å; Y448-I450 VanDerWaalsContact C-N 3.33Å; Y448-I450 PolarHBondContact O-N 3.21Å; I450-V453 PolarHBondContact O-N 2.91Å; I450-A454 WeakPolarHBondContact O-CB 3.29Å; I450-A454 PolarHBondContact O-N 2.86Å
451	V	98.6	Very high	97.5	Very high	20 Å²	20	44.5 Å²	44.5	12%	0.121	24%	0.244	C	C	.	.	H	α-helix	trans	-65	-41.7	179.5	176.7	0	0	0	0	111.1	P142 F305 L447 Y448 A454 T455 W477	P142-V451 HydrophobicContact CB-CB 4.04Å; P142-V451 HydrophobicContact CB-CG1 3.56Å; P142-V451 HydrophobicContact CG-CB 3.91Å; P142-V451 HydrophobicContact CG-CG1 3.95Å; F305-V451 HydrophobicContact CE1-CG1 4.33Å; L447-V451 HydrophobicContact CD1-CG2 4.19Å; L447-V451 VanDerWaalsContact O-CG2 3.3Å; L447-V451 WeakPolarHBondContact O-CG2 3.25Å; L447-V451 PolarHBondContact O-N 3.3Å; Y448-V451 PolarHBondContact O-N 2.8Å; V451-A454 PolarHBondContact O-N 3.34Å; V451-T455 HydrophobicContact CG1-CG2 4.19Å; V451-T455 WeakPolarHBondContact O-CB 3.37Å; V451-T455 VanDerWaalsContact O-CG2 3.28Å; V451-T455 WeakPolarHBondContact O-CG2 3.42Å; V451-T455 PolarHBondContact O-N 3.44Å; V451-T455 PolarHBondContact O-OG1 2.9Å; V451-W477 HydrophobicContact CG1-CH2 4.04Å; V451-W477 HydrophobicContact CG1-CZ2 3.59Å
452	N	98.4	Very high	97.4	Very high	10 Å²	10	49.3 Å²	49.3	5%	0.053	26%	0.264	C	S	.	.	H	α-helix	trans	-61.7	-48.8	175.1	-80.8	-41.5	0	0	0	111.8	T140 P142 Y448 T449 A454 T455 I456	T140-N452 PolarHBondContact O-ND2 3.48Å; P142-N452 WeakPolarHBondContact CA-OD1 3.34Å; Y448-N452 VanDerWaalsContact O-CB 3.3Å; Y448-N452 WeakPolarHBondContact O-CB 3.46Å; Y448-N452 PolarHBondContact O-N 3Å; Y448-N452 PolarHBondContact O-ND2 2.87Å; Y448-N452 VanDerWaalsContact O-ND2 3.1Å; T449-N452 PolarHBondContact O-N 3.4Å; N452-A454 VanDerWaalsContact C-N 3.32Å; N452-A454 PolarHBondContact O-N 2.88Å; N452-T455 PolarHBondContact O-N 3.38Å; N452-T455 PolarHBondContact O-OG1 3.41Å; N452-I456 VanDerWaalsContact O-CB 3.22Å; N452-I456 WeakPolarHBondContact O-CB 3.27Å; N452-I456 VanDerWaalsContact O-CG1 3.23Å; N452-I456 WeakPolarHBondContact O-CG1 3.43Å; N452-I456 PolarHBondContact O-N 3.42Å
453	V	98.3	Very high	97.2	Very high	95 Å²	95	46.9 Å²	46.9	58%	0.576	26%	0.262	S	S	*	.	H	α-helix	trans	-58.1	-46.6	177.1	168.5	0	0	0	0	110.3	T449 I450 Y457	T449-V453 HydrophobicContact CG2-CG2 4.38Å; T449-V453 WeakPolarHBondContact O-CB 3.47Å; T449-V453 VanDerWaalsContact O-CG2 3.25Å; T449-V453 WeakPolarHBondContact O-CG2 3.33Å; T449-V453 PolarHBondContact O-N 3.39Å; I450-V453 PolarHBondContact O-N 2.91Å; V453-Y457 WeakPolarHBondContact O-CB 3.15Å; V453-Y457 PolarHBondContact O-N 3.04Å
454	A	98.1	Very high	97	Very high	47 Å²	47	47.7 Å²	47.7	39%	0.388	26%	0.259	S	S	.	.	H	α-helix	trans	-63	-48.9	179.3	0	0	0	0	0	112.3	I450 V451 N452 Y457 L458	I450-A454 WeakPolarHBondContact O-CB 3.29Å; I450-A454 PolarHBondContact O-N 2.86Å; V451-A454 PolarHBondContact O-N 3.34Å; N452-A454 VanDerWaalsContact C-N 3.32Å; N452-A454 PolarHBondContact O-N 2.88Å; A454-Y457 PolarHBondContact O-N 3.42Å; A454-L458 WeakPolarHBondContact O-CB 3.34Å; A454-L458 VanDerWaalsContact O-CG 3.27Å; A454-L458 WeakPolarHBondContact O-CG 3.41Å; A454-L458 PolarHBondContact O-N 3.37Å
455	T	97.6	Very high	96.6	Very high	9 Å²	9	52.1 Å²	52.1	6%	0.055	29%	0.291	C	S	.	.	H	α-helix	trans	-69.5	-41.2	-176.8	52.4	0	0	0	0	112.5	F358 V451 N452 L458 F459 W477	F358-T455 HydrophobicContact CD2-CG2 4.21Å; F358-T455 HydrophobicContact CE2-CG2 3.42Å; F358-T455 VanDerWaalsContact CE2-CG2 3.42Å; F358-T455 HydrophobicContact CZ-CG2 3.84Å; V451-T455 HydrophobicContact CG1-CG2 4.19Å; V451-T455 WeakPolarHBondContact O-CB 3.37Å; V451-T455 VanDerWaalsContact O-CG2 3.28Å; V451-T455 WeakPolarHBondContact O-CG2 3.42Å; V451-T455 PolarHBondContact O-N 3.44Å; V451-T455 PolarHBondContact O-OG1 2.9Å; N452-T455 PolarHBondContact O-N 3.38Å; N452-T455 PolarHBondContact O-OG1 3.41Å; T455-L458 PolarHBondContact O-N 3.17Å; T455-F459 PolarHBondContact O-N 2.88Å; T455-W477 HydrophobicContact CG2-CH2 4.42Å; T455-W477 HydrophobicContact CG2-CZ2 3.68Å
456	I	97.4	Very high	96.1	Very high	13 Å²	13	53.2 Å²	53.2	7%	0.067	29%	0.293	C	S	.	.	H	α-helix	trans	-66.4	-40.7	173.9	-66.6	171.5	0	0	0	110.7	L26 M30 F146 F149 N452 F459 I460	L26-I456 HydrophobicContact CD1-CD1 4.1Å; M30-I456 HydrophobicContact SD-CG1 4.44Å; M30-I456 HydrophobicContact SD-CG2 4.33Å; F146-I456 HydrophobicContact CD2-CG1 4.33Å; F149-I456 HydrophobicContact CE2-CD1 3.98Å; N452-I456 VanDerWaalsContact O-CB 3.22Å; N452-I456 WeakPolarHBondContact O-CB 3.27Å; N452-I456 VanDerWaalsContact O-CG1 3.23Å; N452-I456 WeakPolarHBondContact O-CG1 3.43Å; N452-I456 PolarHBondContact O-N 3.42Å; I456-F459 PolarHBondContact O-N 3.43Å; I456-I460 HydrophobicContact CG2-CD1 3.51Å; I456-I460 HydrophobicContact CG2-CG1 4.29Å; I456-I460 WeakPolarHBondContact O-CB 3.47Å; I456-I460 WeakPolarHBondContact O-CG1 3.04Å; I456-I460 PolarHBondContact O-N 3.45Å
457	Y	97.4	Very high	95.3	Very high	128 Å²	128	55.7 Å²	55.7	50%	0.502	31%	0.314	S	S	.	.	H	α-helix	trans	-61	-46.6	174.4	171.5	-96.6	0	0	0	111.5	V453 A454 F459 I460 A461 K462	V453-Y457 WeakPolarHBondContact O-CB 3.15Å; V453-Y457 PolarHBondContact O-N 3.04Å; A454-Y457 PolarHBondContact O-N 3.42Å; Y457-F459 VanDerWaalsContact C-N 3.33Å; Y457-F459 PolarHBondContact O-N 2.84Å; Y457-I460 PolarHBondContact O-N 3.14Å; Y457-A461 HydrophobicContact CD2-CB 3.86Å; Y457-A461 HydrophobicContact CE1-CB 4.41Å; Y457-A461 HydrophobicContact CE2-CB 3.52Å; Y457-A461 HydrophobicContact CG-CB 4.43Å; Y457-A461 VanDerWaalsContact O-CB 3.31Å; Y457-A461 WeakPolarHBondContact O-CB 3.33Å; Y457-A461 PolarHBondContact O-N 3.03Å; Y457-K462 HydrophobicContact CE1-CG 4.39Å
458	L	97.1	Very high	94.4	Very high	57 Å²	57	62.6 Å²	62.6	30%	0.298	35%	0.35	S	S	.	.	H	α-helix	trans	-58.7	-45.8	176.5	-72.9	175.4	0	0	0	110.8	F358 A454 T455 I460 K462 F475	F358-L458 HydrophobicContact CE1-CD1 3.79Å; F358-L458 HydrophobicContact CZ-CD1 4.13Å; A454-L458 WeakPolarHBondContact O-CB 3.34Å; A454-L458 VanDerWaalsContact O-CG 3.27Å; A454-L458 WeakPolarHBondContact O-CG 3.41Å; A454-L458 PolarHBondContact O-N 3.37Å; T455-L458 PolarHBondContact O-N 3.17Å; L458-I460 PolarHBondContact O-N 3.19Å; L458-K462 HydrophobicContact CD2-CB 4.25Å; L458-K462 HydrophobicContact CD2-CG 3.82Å; L458-K462 CarbonylContact O-C 3.5Å; L458-K462 WeakPolarHBondContact O-CA 3.41Å; L458-K462 WeakPolarHBondContact O-CB 3.22Å; L458-K462 PolarHBondContact O-N 3.37Å; L458-F475 HydrophobicContact CB-CB 4.27Å
459	F	96.9	Very high	93.4	Very high	0 Å²	0	64.1 Å²	64.1	0%	0	36%	0.363	C	S	.	.	H	α-helix	trans	-61.9	-44.3	177.4	-176.8	-93.6	0	0	0	112.9	M30 Q34 Y38 F146 L150 T455 I456 Y457 R474 F475 M476	M30-F459 HydrophobicContact CE-CD1 3.52Å; M30-F459 HydrophobicContact CE-CE1 3.66Å; M30-F459 HydrophobicContact CE-CG 4.07Å; M30-F459 HydrophobicContact CE-CZ 4.32Å; M30-F459 HydrophobicContact CG-CD1 4.45Å; Q34-F459 HydrophobicContact CB-CE1 4.08Å; Q34-F459 HydrophobicContact CB-CZ 3.99Å; Q34-F459 HydrophobicContact CG-CZ 4.15Å; Y38-F459 AromaticContact CD1-CE2 3.74Å; Y38-F459 HydrophobicContact CD1-CE2 3.74Å; Y38-F459 HydrophobicContact CD1-CZ 4.21Å; Y38-F459 AromaticContact CE1-CE2 3.74Å; Y38-F459 HydrophobicContact CE1-CE2 3.74Å; F146-F459 HydrophobicContact CE2-CB 3.84Å; F146-F459 HydrophobicContact CE2-CD2 4.35Å; F146-F459 HydrophobicContact CE2-CG 4.19Å; F146-F459 HydrophobicContact CZ-CB 3.97Å; F146-F459 AromaticContact CZ-CD2 3.61Å; F146-F459 HydrophobicContact CZ-CD2 3.61Å; F146-F459 HydrophobicContact CZ-CE2 4.28Å; F146-F459 AromaticContact CZ-CG 3.9Å; F146-F459 HydrophobicContact CZ-CG 3.9Å; L150-F459 HydrophobicContact CD2-CZ 4.29Å; T455-F459 PolarHBondContact O-N 2.88Å; I456-F459 PolarHBondContact O-N 3.43Å; Y457-F459 VanDerWaalsContact C-N 3.33Å; Y457-F459 PolarHBondContact O-N 2.84Å; F459-R474 HydrophobicContact CD2-CB 3.84Å; F459-R474 HydrophobicContact CE2-CB 3.97Å; F459-R474 HydrophobicContact CG-CB 4.46Å; F459-R474 WeakPolarHBondContact O-CD 3.48Å; F459-R474 PolarHBondContact O-NH1 2.85Å; F459-F475 WeakPolarHBondContact CA-O 3.17Å; F459-F475 WeakPolarHBondContact CB-O 3.27Å; F459-F475 VanDerWaalsContact CD2-O 3.29Å; F459-F475 WeakPolarHBondContact CD2-O 3.33Å; F459-M476 HydrophobicContact CD2-CB 4.41Å
460	I	96.1	Very high	92.2	Very high	38 Å²	38	70.5 Å²	70.5	20%	0.195	39%	0.394	C	S	.	.	H	α-helix	trans	-76.2	-49.8	-175	-70.6	170.8	0	0	0	111.9	K29 M30 V33 I456 Y457 L458 R474	K29-I460 HydrophobicContact CG-CD1 3.82Å; M30-I460 HydrophobicContact CG-CD1 4.01Å; M30-I460 HydrophobicContact CG-CG1 4.18Å; V33-I460 HydrophobicContact CG1-CG2 4.42Å; V33-I460 HydrophobicContact CG2-CG2 4.08Å; I456-I460 HydrophobicContact CG2-CD1 3.51Å; I456-I460 HydrophobicContact CG2-CG1 4.29Å; I456-I460 WeakPolarHBondContact O-CB 3.47Å; I456-I460 WeakPolarHBondContact O-CG1 3.04Å; I456-I460 PolarHBondContact O-N 3.45Å; Y457-I460 PolarHBondContact O-N 3.14Å; L458-I460 PolarHBondContact O-N 3.19Å; I460-R474 PolarHBondContact O-NH1 2.79Å
461	A	95.6	Very high	91.4	Very high	52 Å²	52	70.2 Å²	70.2	43%	0.43	40%	0.397	S	S	.	.	H	α-helix	trans	-99.9	-21.9	-166.2	0	0	0	0	0	113.7	Y457	Y457-A461 HydrophobicContact CD2-CB 3.86Å; Y457-A461 HydrophobicContact CE1-CB 4.41Å; Y457-A461 HydrophobicContact CE2-CB 3.52Å; Y457-A461 HydrophobicContact CG-CB 4.43Å; Y457-A461 VanDerWaalsContact O-CB 3.31Å; Y457-A461 WeakPolarHBondContact O-CB 3.33Å; Y457-A461 PolarHBondContact O-N 3.03Å
462	K	94.4	Very high	90.9	Very high	101 Å²	101	72.6 Å²	72.6	44%	0.439	41%	0.412	S	S	.	.			trans	-109.1	113.6	179	-59.9	-60.9	-174.6	178.6	0	109.9	Y457 L458 F475	Y457-K462 HydrophobicContact CE1-CG 4.39Å; L458-K462 HydrophobicContact CD2-CB 4.25Å; L458-K462 HydrophobicContact CD2-CG 3.82Å; L458-K462 CarbonylContact O-C 3.5Å; L458-K462 WeakPolarHBondContact O-CA 3.41Å; L458-K462 WeakPolarHBondContact O-CB 3.22Å; L458-K462 PolarHBondContact O-N 3.37Å; K462-F475 HydrophobicContact CB-CD2 4.01Å; K462-F475 HydrophobicContact CB-CE2 4.14Å
463	S	92.5	Very high	90.6	Very high	67 Å²	67	72.4 Å²	72.4	47%	0.469	41%	0.411	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-129	159.5	176.7	67.7	0	0	0	0	110.6	Q473	S463-Q473 VanDerWaalsContact CA-O 3.25Å; S463-Q473 WeakPolarHBondContact CA-O 3.25Å; S463-Q473 WeakPolarHBondContact CB-O 3.4Å
464	F	92.2	Very high	90.4	Very high	39 Å²	39	69.2 Å²	69.2	17%	0.171	39%	0.388	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-147.9	161.5	178.4	60.6	-84.6	0	0	0	110	N355 R356 W466 Q473 F475	N355-F464 WeakPolarHBondContact OD1-CE2 3.14Å; N355-F464 VanDerWaalsContact OD1-CZ 3.31Å; N355-F464 WeakPolarHBondContact OD1-CZ 3.32Å; R356-F464 HydrophobicContact CG-CE1 4.47Å; R356-F464 HydrophobicContact CG-CE2 4.4Å; R356-F464 HydrophobicContact CG-CZ 3.64Å; F464-W466 HydrophobicContact CE2-CZ2 4.45Å; F464-W466 AromaticContact CE2-NE1 3.46Å; F464-Q473 HydrophobicContact CD1-CB 4.38Å; F464-Q473 HydrophobicContact CD2-CB 3.9Å; F464-Q473 HydrophobicContact CE1-CB 4.06Å; F464-Q473 HydrophobicContact CE2-CB 3.53Å; F464-Q473 HydrophobicContact CE2-CG 4.14Å; F464-Q473 HydrophobicContact CG-CB 4.32Å; F464-Q473 HydrophobicContact CZ-CB 3.65Å; F464-Q473 PolarHBondContact N-O 3.48Å; F464-Q473 WeakPolarHBondContact O-CA 3.23Å; F464-Q473 WeakPolarHBondContact O-CB 3.22Å; F464-Q473 PolarHBondContact O-N 3.01Å; F464-F475 HydrophobicContact CD1-CD2 4.47Å; F464-F475 AromaticContact CD1-CE1 3.88Å; F464-F475 HydrophobicContact CD1-CE1 3.88Å; F464-F475 AromaticContact CD1-CE2 3.81Å; F464-F475 HydrophobicContact CD1-CE2 3.81Å; F464-F475 AromaticContact CD1-CZ 3.48Å; F464-F475 HydrophobicContact CD1-CZ 3.48Å; F464-F475 VanDerWaalsContact CD1-CZ 3.48Å; F464-F475 AromaticContact CE1-CD1 3.79Å; F464-F475 HydrophobicContact CE1-CD1 3.79Å; F464-F475 HydrophobicContact CE1-CD2 4.36Å; F464-F475 AromaticContact CE1-CE1 3.33Å; F464-F475 HydrophobicContact CE1-CE1 3.33Å; F464-F475 AromaticContact CE1-CE2 4Å; F464-F475 HydrophobicContact CE1-CE2 4Å; F464-F475 HydrophobicContact CE1-CG 4.27Å; F464-F475 AromaticContact CE1-CZ 3.47Å; F464-F475 HydrophobicContact CE1-CZ 3.47Å; F464-F475 VanDerWaalsContact CE1-CZ 3.47Å; F464-F475 HydrophobicContact CG-CZ 4.49Å; F464-F475 HydrophobicContact CZ-CE1 4.06Å; F464-F475 HydrophobicContact CZ-CZ 4.46Å
465	S	87.9	Confident	90.3	Very high	94 Å²	94	68.9 Å²	68.9	66%	0.657	38%	0.378	S	S	*	.			trans	-114.9	145.4	175	50.4	0	0	0	0	109.9
466	W	87.8	Confident	90.2	Very high	82 Å²	82	68.5 Å²	68.5	31%	0.311	38%	0.376	S	S	.	.			trans	-92.7	147.5	162.8	-65.9	-32.8	0	0	0	108.9	N355 R356 F464 L468 A469 Q473	N355-W466 WeakPolarHBondContact OD1-CZ2 3.26Å; N355-W466 PolarHBondContact OD1-NE1 2.89Å; R356-W466 HydrophobicContact CG-CH2 4.41Å; R356-W466 HydrophobicContact CG-CZ2 4.17Å; F464-W466 HydrophobicContact CE2-CZ2 4.45Å; F464-W466 AromaticContact CE2-NE1 3.46Å; W466-L468 PolarHBondContact O-N 3.41Å; W466-A469 HydrophobicContact CB-CB 3.83Å; W466-A469 HydrophobicContact CE3-CB 4.19Å; W466-A469 PolarHBondContact O-N 3.43Å; W466-Q473 HydrophobicContact CD2-CG 4.15Å; W466-Q473 HydrophobicContact CE3-CG 4.22Å
467	P	82	Confident	89.9	Confident	137 Å²	137	68.6 Å²	68.6	89%	0.89	38%	0.376	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.4	-27.6	-178	-27.4	34.6	0	0	0	114.7
468	L	78.4	Confident	89.6	Confident	177 Å²	177	65.7 Å²	65.7	93%	0.927	37%	0.369	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.6	-1.1	-177.6	-63.7	168.9	0	0	0	113.6	W466	W466-L468 PolarHBondContact O-N 3.41Å
469	A	76.8	Confident	89.2	Confident	32 Å²	32	66.1 Å²	66.1	26%	0.264	37%	0.373	S	S	.	.			trans	-92	126.5	-177.3	0	0	0	0	0	111.2	W466 T471	W466-A469 HydrophobicContact CB-CB 3.83Å; W466-A469 HydrophobicContact CE3-CB 4.19Å; W466-A469 PolarHBondContact O-N 3.43Å; A469-T471 PolarHBondContact O-N 3.39Å
470	L	73.6	Confident	88.7	Confident	183 Å²	183	69.8 Å²	69.8	96%	0.958	39%	0.394	S	S	*	.	S	Bend	trans	-70.9	-17.6	173.8	-67.9	166	0	0	0	112.8
471	T	82.4	Confident	88.3	Confident	93 Å²	93	71.6 Å²	71.6	57%	0.571	41%	0.405	S	S	*	.	S	Bend	trans	-118.3	147.2	-174.8	57.9	0	0	0	0	112.3	A469 Q473	A469-T471 PolarHBondContact O-N 3.39Å; T471-Q473 PolarHBondContact O-NE2 3.29Å; T471-Q473 PolarHBondContact OG1-NE2 2.92Å; T471-Q473 VanDerWaalsContact OG1-NE2 3.17Å
472	T	87.6	Confident	87.8	Confident	70 Å²	70	72.9 Å²	72.9	43%	0.429	40%	0.404	S	S	.	.			trans	-66.3	130.3	173.8	-58.3	0	0	0	0	110.7
473	Q	92.6	Very high	87.4	Confident	7 Å²	7	71 Å²	71	3%	0.033	40%	0.401	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.9	153.4	177.2	-52.1	-53.3	-50.3	0	0	111.1	R356 S463 F464 W466 T471	R356-Q473 HydrophobicContact CG-CB 4.19Å; S463-Q473 VanDerWaalsContact CA-O 3.25Å; S463-Q473 WeakPolarHBondContact CA-O 3.25Å; S463-Q473 WeakPolarHBondContact CB-O 3.4Å; F464-Q473 HydrophobicContact CD1-CB 4.38Å; F464-Q473 HydrophobicContact CD2-CB 3.9Å; F464-Q473 HydrophobicContact CE1-CB 4.06Å; F464-Q473 HydrophobicContact CE2-CB 3.53Å; F464-Q473 HydrophobicContact CE2-CG 4.14Å; F464-Q473 HydrophobicContact CG-CB 4.32Å; F464-Q473 HydrophobicContact CZ-CB 3.65Å; F464-Q473 PolarHBondContact N-O 3.48Å; F464-Q473 WeakPolarHBondContact O-CA 3.23Å; F464-Q473 WeakPolarHBondContact O-CB 3.22Å; F464-Q473 PolarHBondContact O-N 3.01Å; W466-Q473 HydrophobicContact CD2-CG 4.15Å; W466-Q473 HydrophobicContact CE3-CG 4.22Å; T471-Q473 PolarHBondContact O-NE2 3.29Å; T471-Q473 PolarHBondContact OG1-NE2 2.92Å; T471-Q473 VanDerWaalsContact OG1-NE2 3.17Å
474	R	94.7	Very high	87	Confident	27 Å²	27	71.3 Å²	71.3	10%	0.102	40%	0.397	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-138.6	149	-174.4	-64	178	176.3	-73.6	-5.7	111.3	V33 Y38 F459 I460	V33-R474 PolarHBondContact O-NH2 3Å; Y38-R474 HydrophobicContact CE1-CB 4.31Å; Y38-R474 WeakPolarHBondContact OH-CA 3.43Å; Y38-R474 PolarHBondContact OH-N 2.89Å; Y38-R474 PolarHBondContact OH-O 3.25Å; F459-R474 HydrophobicContact CD2-CB 3.84Å; F459-R474 HydrophobicContact CE2-CB 3.97Å; F459-R474 HydrophobicContact CG-CB 4.46Å; F459-R474 WeakPolarHBondContact O-CD 3.48Å; F459-R474 PolarHBondContact O-NH1 2.85Å; I460-R474 PolarHBondContact O-NH1 2.79Å
475	F	95.6	Very high	86.6	Confident	41 Å²	41	73.8 Å²	73.8	18%	0.18	41%	0.414	C	S	.	.			trans	-77.7	137.9	177.6	-61.7	-66.9	0	0	0	112.2	R356 F358 Y361 L458 F459 K462 F464	R356-F475 CarbonylContact O-C 3.56Å; R356-F475 VanDerWaalsContact O-CA 3.3Å; R356-F475 WeakPolarHBondContact O-CA 3.05Å; F358-F475 HydrophobicContact CE1-CB 3.83Å; F358-F475 HydrophobicContact CZ-CB 4.28Å; Y361-F475 AromaticContact CE2-CD1 3.97Å; Y361-F475 HydrophobicContact CE2-CD1 3.97Å; Y361-F475 AromaticContact CE2-CE1 3.76Å; Y361-F475 HydrophobicContact CE2-CE1 3.76Å; Y361-F475 AromaticContact CZ-CE1 3.83Å; Y361-F475 WeakPolarHBondContact OH-CE1 3.36Å; L458-F475 HydrophobicContact CB-CB 4.27Å; F459-F475 WeakPolarHBondContact CA-O 3.17Å; F459-F475 WeakPolarHBondContact CB-O 3.27Å; F459-F475 VanDerWaalsContact CD2-O 3.29Å; F459-F475 WeakPolarHBondContact CD2-O 3.33Å; K462-F475 HydrophobicContact CB-CD2 4.01Å; K462-F475 HydrophobicContact CB-CE2 4.14Å; F464-F475 HydrophobicContact CD1-CD2 4.47Å; F464-F475 AromaticContact CD1-CE1 3.88Å; F464-F475 HydrophobicContact CD1-CE1 3.88Å; F464-F475 AromaticContact CD1-CE2 3.81Å; F464-F475 HydrophobicContact CD1-CE2 3.81Å; F464-F475 AromaticContact CD1-CZ 3.48Å; F464-F475 HydrophobicContact CD1-CZ 3.48Å; F464-F475 VanDerWaalsContact CD1-CZ 3.48Å; F464-F475 AromaticContact CE1-CD1 3.79Å; F464-F475 HydrophobicContact CE1-CD1 3.79Å; F464-F475 HydrophobicContact CE1-CD2 4.36Å; F464-F475 AromaticContact CE1-CE1 3.33Å; F464-F475 HydrophobicContact CE1-CE1 3.33Å; F464-F475 AromaticContact CE1-CE2 4Å; F464-F475 HydrophobicContact CE1-CE2 4Å; F464-F475 HydrophobicContact CE1-CG 4.27Å; F464-F475 AromaticContact CE1-CZ 3.47Å; F464-F475 HydrophobicContact CE1-CZ 3.47Å; F464-F475 VanDerWaalsContact CE1-CZ 3.47Å; F464-F475 HydrophobicContact CG-CZ 4.49Å; F464-F475 HydrophobicContact CZ-CE1 4.06Å; F464-F475 HydrophobicContact CZ-CZ 4.46Å
476	M	94.9	Very high	86.5	Confident	0 Å²	0	72.1 Å²	72.1	0%	0	39%	0.394	C	S	.	.	B	Isolated β-bridge	trans	-146.2	173.9	177	63.5	178.3	-82	0	0	112.5	Y38 M39 F146 F147 L150 R356 H357 F358 F459	Y38-M476 HydrophobicContact CD1-SD 4.16Å; Y38-M476 HydrophobicContact CE1-CG 4.49Å; Y38-M476 HydrophobicContact CE1-SD 3.72Å; M39-M476 HydrophobicContact CB-SD 4.33Å; M39-M476 HydrophobicContact CE-SD 4.24Å; M39-M476 HydrophobicContact CG-SD 3.5Å; M39-M476 WeakPolarHBondContact CG-SD 3.33Å; M39-M476 HydrophobicContact SD-SD 4.31Å; F146-M476 HydrophobicContact CE1-CB 3.49Å; F146-M476 VanDerWaalsContact CE1-CB 3.49Å; F146-M476 HydrophobicContact CZ-CB 3.5Å; F147-M476 HydrophobicContact CE1-CE 3.37Å; F147-M476 HydrophobicContact CZ-CE 3.65Å; L150-M476 HydrophobicContact CD1-CE 4.36Å; R356-M476 PolarHBondContact O-N 3.23Å; H357-M476 CarbonylContact C-O 3.48Å; H357-M476 VanDerWaalsContact CA-O 3.31Å; H357-M476 WeakPolarHBondContact CA-O 3.22Å; F358-M476 WeakPolarHBondContact CD2-O 3.31Å; F358-M476 WeakPolarHBondContact CE2-O 3.4Å; F358-M476 WeakPolarHBondContact CG-O 3.39Å; F358-M476 PolarHBondContact N-O 2.99Å; F459-M476 HydrophobicContact CD2-CB 4.41Å
477	W	92.1	Very high	86.4	Confident	16 Å²	16	71.2 Å²	71.2	6%	0.061	40%	0.401	C	S	.	.			trans	-63.3	0	173.3	-81.2	108.3	0	0	0	113.4	P142 V143 F146 F147 F305 H357 F358 P359 F419 V451 T455	P142-W477 HydrophobicContact CB-CZ2 4.1Å; P142-W477 PolarHBondContact O-NE1 2.89Å; V143-W477 HydrophobicContact CG1-CD2 4.5Å; V143-W477 HydrophobicContact CG1-CG 4.39Å; V143-W477 HydrophobicContact CG2-CD2 4.07Å; V143-W477 HydrophobicContact CG2-CE3 4.11Å; V143-W477 HydrophobicContact CG2-CH2 4.3Å; V143-W477 HydrophobicContact CG2-CZ2 4.21Å; V143-W477 HydrophobicContact CG2-CZ3 4.25Å; F146-W477 AromaticContact CD1-CD1 3.88Å; F146-W477 AromaticContact CD2-CD1 3.92Å; F146-W477 AromaticContact CG-CD1 3.45Å; F146-W477 VanDerWaalsContact CG-CD1 3.45Å; F147-W477 HydrophobicContact CE2-CB 3.49Å; F147-W477 VanDerWaalsContact CE2-CB 3.49Å; F147-W477 HydrophobicContact CE2-CG 4.37Å; F147-W477 HydrophobicContact CZ-CB 3.79Å; F305-W477 AromaticContact CZ-CH2 3.89Å; F305-W477 HydrophobicContact CZ-CH2 3.89Å; F305-W477 HydrophobicContact CZ-CZ2 4.42Å; H357-W477 PolarHBondContact CD2-O 3.26Å; F358-W477 HydrophobicContact CB-CE3 4.41Å; F358-W477 HydrophobicContact CD2-CB 4.42Å; F358-W477 AromaticContact CD2-CD2 3.68Å; F358-W477 HydrophobicContact CD2-CD2 3.68Å; F358-W477 AromaticContact CD2-CE3 3.59Å; F358-W477 HydrophobicContact CD2-CE3 3.59Å; F358-W477 HydrophobicContact CD2-CG 4.04Å; F358-W477 HydrophobicContact CD2-CZ3 4.03Å; F358-W477 HydrophobicContact CE2-CD2 4.06Å; F358-W477 HydrophobicContact CE2-CE3 4.41Å; F358-W477 HydrophobicContact CE2-CG 4.16Å; F358-W477 HydrophobicContact CG-CE3 4.49Å; P359-W477 WeakPolarHBondContact CD-OXT 3.49Å; F419-W477 AromaticContact CD2-CE3 3.74Å; F419-W477 HydrophobicContact CD2-CE3 3.74Å; F419-W477 AromaticContact CD2-CZ3 3.58Å; F419-W477 HydrophobicContact CD2-CZ3 3.58Å; F419-W477 HydrophobicContact CE2-CE3 4.48Å; F419-W477 HydrophobicContact CE2-CZ3 4.01Å; V451-W477 HydrophobicContact CG1-CH2 4.04Å; V451-W477 HydrophobicContact CG1-CZ2 3.59Å; T455-W477 HydrophobicContact CG2-CH2 4.42Å; T455-W477 HydrophobicContact CG2-CZ2 3.68Å

Retrieved 477 of 477 residues in 395.8 ms (Link to these results)

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