A0A087XQI5_POEFO Loading...

Anoctamin

AlphaFold DB , UniProt , Accession A0A087XQI5, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 650 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M33.9Very low43.1Very low250 Ų250132 Ų132100%1.23278%0.781SS**  093.20-104.8173.2163.200107.8
2Q25.7Very low46.8Very low197 Ų197123.1 Ų123.192%0.92173%0.725SS**  trans-15398.2164.1-125.8163.4-9.100104.2S4Q2-S4 PolarHBondContact O-N 3.46Å
3Q27.2Very low50Low193 Ų193122.2 Ų122.290%0.90272%0.715SS**  trans-64.6116.6172.8-83.9166.8-43.900107.1D5Q3-D5 PolarHBondContact O-N 3.18Å
4S29.6Very low52.9Low105 Ų105114.3 Ų114.373%0.73467%0.669SS**  trans-66.9107.6158.849.10000107.4Q2 D6Q2-S4 PolarHBondContact O-N 3.46Å; S4-D6 VanDerWaalsContact C-N 3.27Å; S4-D6 PolarHBondContact O-N 3.42Å
5D31.8Very low55.7Low167 Ų167107.3 Ų107.389%0.89363%0.628SS**  trans-61.494.9160.1-91.7-30.4000107.4Q3 S7Q3-D5 PolarHBondContact O-N 3.18Å; D5-S7 PolarHBondContact O-N 3.23Å
6D35.4Very low58.2Low148 Ų148100.6 Ų100.679%0.79159%0.589SS**  trans-78.7107.6172.1-139-0.5000107.3S4 G8S4-D6 VanDerWaalsContact C-N 3.27Å; S4-D6 PolarHBondContact O-N 3.42Å; D6-G8 PolarHBondContact O-N 3.01Å
7S38.9Very low60.4Low93 Ų9394.7 Ų94.765%0.6555%0.554SS**  trans-49.2130.6171.749.30000110.1D5 A9D5-S7 PolarHBondContact O-N 3.23Å; S7-A9 PolarHBondContact O-N 2.88Å
8G51Low62.4Low90 Ų9089.6 Ų89.693%0.92852%0.524SS*.SBendtrans-66.643.4-177.600000116.5D6D6-G8 PolarHBondContact O-N 3.01Å
9A57.2Low64.1Low74 Ų7486.3 Ų86.361%0.61250%0.503SS*.  trans-83.5140.5167.100000109.4S7S7-A9 PolarHBondContact O-N 2.88Å
10P63.6Low65.5Low36 Ų3682.2 Ų82.223%0.23448%0.479CS..  trans-63.3151.3177.428.7-35.5000111F12 P14 E50 L68 L477P10-F12 WeakPolarHBondContact CB-O 3.46Å; P10-F12 WeakPolarHBondContact CG-O 3.26Å; P10-F12 PolarHBondContact O-N 3.39Å; P10-P14 HydrophobicContact CG-CG 4.11Å; P10-E50 WeakPolarHBondContact CA-OE2 3.07Å; P10-L68 HydrophobicContact CB-CD1 4.5Å; P10-L477 HydrophobicContact CB-CD2 4.49Å; P10-L477 HydrophobicContact CG-CD2 3.64Å
11S79.4Confident66.8Low99 Ų9981.1 Ų81.169%0.69247%0.471SS*.SBendtrans-70.6-11-178.774.80000113.6E50S11-E50 WeakPolarHBondContact CB-OE1 3.15Å; S11-E50 PolarHBondContact N-OE2 2.8Å; S11-E50 PolarHBondContact OG-OE1 2.88Å
12F88.1Confident69.3Low25 Ų2572.6 Ų72.611%0.1144%0.436CS..SBendtrans-142.4167.3178.362.6-92.8000110.6P10 P14 L48 E50 G70P10-F12 WeakPolarHBondContact CB-O 3.46Å; P10-F12 WeakPolarHBondContact CG-O 3.26Å; P10-F12 PolarHBondContact O-N 3.39Å; F12-P14 VanDerWaalsContact O-CD 3.23Å; F12-P14 WeakPolarHBondContact O-CD 3.28Å; F12-L48 HydrophobicContact CB-CD1 3.74Å; F12-L48 HydrophobicContact CD1-CB 3.68Å; F12-L48 HydrophobicContact CD1-CD1 4.06Å; F12-L48 HydrophobicContact CD1-CG 4.49Å; F12-L48 HydrophobicContact CD2-CB 4.25Å; F12-L48 HydrophobicContact CE1-CB 3.71Å; F12-L48 HydrophobicContact CE2-CB 4.32Å; F12-L48 HydrophobicContact CG-CB 3.96Å; F12-L48 HydrophobicContact CG-CD1 3.88Å; F12-L48 HydrophobicContact CZ-CB 4.05Å; F12-E50 HydrophobicContact CE1-CB 4.03Å; F12-E50 HydrophobicContact CE1-CG 3.73Å; F12-E50 HydrophobicContact CZ-CB 4.3Å; F12-E50 HydrophobicContact CZ-CG 4.48Å; F12-G70 VanDerWaalsContact CE2-CA 3.49Å
13N87.6Confident72.2Confident112 Ų11268.7 Ų68.760%0.59942%0.421SS*.  trans-72.9112.7176.5-17210.9000111.1
14P91.4Very high75.2Confident11 Ų1160 Ų607%0.07138%0.381CS..  trans-75.7128.1-177.332.7-35.8000111P10 F12 L68 L170 L477P10-P14 HydrophobicContact CG-CG 4.11Å; F12-P14 VanDerWaalsContact O-CD 3.23Å; F12-P14 WeakPolarHBondContact O-CD 3.28Å; P14-L68 HydrophobicContact CB-CB 4.05Å; P14-L68 HydrophobicContact CB-CD1 4.07Å; P14-L68 HydrophobicContact CB-CD2 4.31Å; P14-L68 HydrophobicContact CB-CG 4.37Å; P14-L170 HydrophobicContact CB-CD1 4.05Å; P14-L170 HydrophobicContact CG-CD1 4.24Å; P14-L477 HydrophobicContact CG-CD1 4.06Å; P14-L477 HydrophobicContact CG-CD2 3.83Å
15L94.2Very high78.2Confident10 Ų1060.2 Ų60.25%0.05237%0.369CS..  trans-114.4-40.3-174.8-68.6174000112.7V69 M118 C121 Q122 I125 L170L15-V69 PolarHBondContact N-O 2.93Å; L15-M118 HydrophobicContact CD2-CE 3.82Å; L15-M118 HydrophobicContact CD2-CG 3.99Å; L15-C121 HydrophobicContact CD1-CB 3.81Å; L15-Q122 HydrophobicContact CB-CG 4.03Å; L15-Q122 HydrophobicContact CD2-CG 4.42Å; L15-Q122 PolarHBondContact O-NE2 2.72Å; L15-I125 HydrophobicContact CB-CD1 3.7Å; L15-I125 HydrophobicContact CD1-CD1 3.46Å; L15-I125 VanDerWaalsContact CD1-CD1 3.46Å; L15-I125 HydrophobicContact CG-CD1 4.18Å; L15-L170 PolarHBondContact O-N 3.04Å
16V96.7Very high81Confident0 Ų060.2 Ų60.20%036%0.364CS..EExtended strand (participates in β ladder)trans-128.4145.6-176.7177.20000109.9V69 Q122 I125 L129 M167 F544V16-V69 HydrophobicContact CB-CB 4.33Å; V16-V69 PolarHBondContact N-O 3.45Å; V16-V69 VanDerWaalsContact N-O 3.08Å; V16-V69 PolarHBondContact O-N 2.96Å; V16-Q122 HydrophobicContact CG2-CB 4.45Å; V16-Q122 HydrophobicContact CG2-CG 4.39Å; V16-I125 HydrophobicContact CB-CG2 3.98Å; V16-I125 HydrophobicContact CG2-CB 4.05Å; V16-I125 HydrophobicContact CG2-CG2 3.65Å; V16-L129 HydrophobicContact CG1-CD1 4.47Å; V16-M167 HydrophobicContact CG1-CG 3.8Å; V16-F544 HydrophobicContact CG1-CE1 4.43Å; V16-F544 HydrophobicContact CG1-CZ 4.05Å; V16-F544 HydrophobicContact CG2-CE1 3.96Å; V16-F544 HydrophobicContact CG2-CZ 4.41Å
17V95.6Very high83.7Confident0 Ų059.7 Ų59.70%036%0.356CS..EExtended strand (participates in β ladder)trans-112.4135.8176.1-175.70000109.7L66 F67 L68 M167 F168 L170 V481V17-L66 HydrophobicContact CG1-CD2 3.91Å; V17-F67 CarbonylContact C-O 3.59Å; V17-F67 WeakPolarHBondContact CA-O 3.3Å; V17-L68 HydrophobicContact CG2-CD2 4.02Å; V17-M167 WeakPolarHBondContact O-CA 3.37Å; V17-F168 HydrophobicContact CB-CD1 4.34Å; V17-F168 HydrophobicContact CB-CD2 4.41Å; V17-F168 HydrophobicContact CB-CE1 3.89Å; V17-F168 HydrophobicContact CB-CE2 3.97Å; V17-F168 HydrophobicContact CB-CZ 3.69Å; V17-F168 HydrophobicContact CG1-CE1 3.91Å; V17-F168 HydrophobicContact CG1-CZ 3.79Å; V17-F168 HydrophobicContact CG2-CE2 3.94Å; V17-F168 HydrophobicContact CG2-CZ 4.01Å; V17-F168 PolarHBondContact N-O 3.12Å; V17-F168 PolarHBondContact O-N 3.03Å; V17-F168 VanDerWaalsContact O-N 3.12Å; V17-L170 HydrophobicContact CG2-CD1 3.95Å; V17-L170 HydrophobicContact CG2-CD2 3.64Å; V17-L170 HydrophobicContact CG2-CG 3.66Å; V17-V481 HydrophobicContact CG1-CG1 3.89Å; V17-V481 HydrophobicContact CG2-CG1 3.98Å; V17-V481 HydrophobicContact CG2-CG2 4.47Å
18L95.4Very high86.3Confident3 Ų355.5 Ų55.52%0.01633%0.327CS..EExtended strand (participates in β ladder)trans-110.3124.3168.5-60.7175.4000109.1I36 F67 V69 L129 L164 M167L18-I36 HydrophobicContact CD1-CD1 3.8Å; L18-F67 HydrophobicContact CB-CB 4.33Å; L18-F67 PolarHBondContact N-O 3.21Å; L18-F67 PolarHBondContact O-N 2.98Å; L18-V69 HydrophobicContact CD1-CG2 3.67Å; L18-V69 HydrophobicContact CG-CG2 3.86Å; L18-L129 HydrophobicContact CD2-CD1 4.37Å; L18-L164 HydrophobicContact CB-CD1 4.1Å; L18-L164 HydrophobicContact CD2-CD1 4.18Å; L18-L164 HydrophobicContact CD2-CD2 4.42Å; L18-M167 HydrophobicContact CD2-CB 3.85Å; L18-M167 HydrophobicContact CD2-CG 3.65Å; L18-M167 HydrophobicContact CD2-SD 4.05Å
19E94.3Very high88.3Confident27 Ų2752.2 Ų52.213%0.12629%0.288CS..EExtended strand (participates in β ladder)trans-110.8111.3174.9-173.6179.7179.700110.3N63 L66 L164 I165 Q166E19-N63 PolarHBondContact OE1-ND2 3.37Å; E19-L66 HydrophobicContact CB-CD2 3.77Å; E19-L66 HydrophobicContact CG-CD2 3.73Å; E19-L66 HydrophobicContact CG-CG 4.48Å; E19-L164 WeakPolarHBondContact O-CD1 3.34Å; E19-I165 HydrophobicContact CG-CB 4.39Å; E19-I165 HydrophobicContact CG-CD1 4.26Å; E19-I165 WeakPolarHBondContact O-CB 3.42Å; E19-I165 PolarHBondContact O-N 3.47Å; E19-Q166 HydrophobicContact CB-CG 3.85Å; E19-Q166 PolarHBondContact N-O 2.85Å; E19-Q166 PolarHBondContact O-N 2.99Å; E19-Q166 WeakPolarHBondContact OE2-CG 3.35Å; E19-Q166 PolarHBondContact OE2-NE2 3.26Å
20L93.4Very high90.1Very high4 Ų451.5 Ų51.52%0.02128%0.282CS..EExtended strand (participates in β ladder)trans-92.6158.9172.6-56.7174.2000110.2T24 I29 L32 N63 N65 F67 I163 L164L20-T24 HydrophobicContact CD1-CG2 4.35Å; L20-I29 HydrophobicContact CD1-CG1 3.93Å; L20-L32 HydrophobicContact CD1-CD2 4.27Å; L20-L32 HydrophobicContact CD2-CD2 4.09Å; L20-N63 PolarHBondContact O-ND2 2.96Å; L20-N65 HydrophobicContact CB-CB 3.97Å; L20-N65 PolarHBondContact N-O 2.89Å; L20-F67 HydrophobicContact CD1-CD2 4.13Å; L20-F67 HydrophobicContact CD1-CE2 3.61Å; L20-F67 HydrophobicContact CD1-CZ 4.46Å; L20-F67 HydrophobicContact CG-CD2 4.35Å; L20-F67 HydrophobicContact CG-CE2 4.14Å; L20-I163 WeakPolarHBondContact CA-O 3.49Å; L20-L164 HydrophobicContact CD2-CB 4.02Å; L20-L164 HydrophobicContact CD2-CD1 3.66Å; L20-L164 HydrophobicContact CD2-CG 4.46Å; L20-L164 HydrophobicContact CG-CD1 4.5Å
21I92.5Very high91.5Very high59 Ų5951.4 Ų51.430%0.30328%0.278SS..  trans-64.1145.2175.3-167.1170.7000111.3D23 T24 N65 I163 I165I21-D23 WeakPolarHBondContact CD1-OD1 3.1Å; I21-D23 VanDerWaalsContact CG1-OD1 3.22Å; I21-D23 WeakPolarHBondContact CG1-OD1 3.31Å; I21-D23 WeakPolarHBondContact CG2-OD1 3.48Å; I21-D23 PolarHBondContact O-N 3.25Å; I21-D23 VanDerWaalsContact O-N 3.14Å; I21-T24 WeakPolarHBondContact CG2-OG1 3.31Å; I21-T24 PolarHBondContact N-OG1 2.82Å; I21-T24 WeakPolarHBondContact O-CB 3.26Å; I21-T24 PolarHBondContact O-N 3.49Å; I21-T24 PolarHBondContact O-OG1 3.04Å; I21-N65 PolarHBondContact O-ND2 2.97Å; I21-I163 PolarHBondContact N-O 2.85Å; I21-I165 HydrophobicContact CB-CD1 4.31Å; I21-I165 HydrophobicContact CB-CG1 4.34Å
22S86.4Confident92.2Very high71 Ų7147 Ų4750%0.49725%0.246SC..THydrogen-bonded Turntrans-59.3-28.1-173.6-48.80000114T24 N63 N65S22-T24 VanDerWaalsContact C-N 3.32Å; S22-N63 WeakPolarHBondContact CA-OD1 3.46Å; S22-N63 PolarHBondContact OG-OD1 3.11Å; S22-N65 PolarHBondContact O-ND2 3.42Å
23D87.3Confident92.5Very high115 Ų11547.1 Ų47.162%0.61525%0.248SC*.THydrogen-bonded Turntrans-92.715.2179.770.5-21.8000113.3I21 K25I21-D23 WeakPolarHBondContact CD1-OD1 3.1Å; I21-D23 VanDerWaalsContact CG1-OD1 3.22Å; I21-D23 WeakPolarHBondContact CG1-OD1 3.31Å; I21-D23 WeakPolarHBondContact CG2-OD1 3.48Å; I21-D23 PolarHBondContact O-N 3.25Å; I21-D23 VanDerWaalsContact O-N 3.14Å; D23-K25 PolarHBondContact O-N 2.62Å
24T88.8Confident92.8Very high10 Ų1044.8 Ų44.86%0.06124%0.24CC..  trans-62.1127.8179.3-55.10000110.9L20 I21 S22 A28 I29 Y143 I163L20-T24 HydrophobicContact CD1-CG2 4.35Å; I21-T24 WeakPolarHBondContact CG2-OG1 3.31Å; I21-T24 PolarHBondContact N-OG1 2.82Å; I21-T24 WeakPolarHBondContact O-CB 3.26Å; I21-T24 PolarHBondContact O-N 3.49Å; I21-T24 PolarHBondContact O-OG1 3.04Å; S22-T24 VanDerWaalsContact C-N 3.32Å; T24-A28 HydrophobicContact CG2-CB 4.14Å; T24-I29 HydrophobicContact CG2-CD1 4.24Å; T24-I29 HydrophobicContact CG2-CG1 3.7Å; T24-Y143 WeakPolarHBondContact CA-OH 3.44Å; T24-Y143 HydrophobicContact CG2-CE2 4.41Å; T24-I163 HydrophobicContact CG2-CG2 4Å
25K92Very high93Very high110 Ų11045.4 Ų45.448%0.47824%0.241SC..  trans-61.2136177.8-66.1179.1175.5-171.40111.4D23 E27 A28 I29 G142 Y143D23-K25 PolarHBondContact O-N 2.62Å; K25-E27 PolarHBondContact O-N 3.12Å; K25-A28 HydrophobicContact CB-CB 4.5Å; K25-A28 WeakPolarHBondContact O-CB 3.27Å; K25-A28 PolarHBondContact O-N 3.3Å; K25-I29 PolarHBondContact O-N 3.21Å; K25-G142 VanDerWaalsContact CD-O 3.31Å; K25-G142 WeakPolarHBondContact CD-O 3.5Å; K25-G142 VanDerWaalsContact CE-O 3.31Å; K25-G142 WeakPolarHBondContact CE-O 3Å; K25-G142 PolarHBondContact NZ-O 2.82Å; K25-Y143 HydrophobicContact CB-CE2 4.39Å; K25-Y143 HydrophobicContact CD-CE2 4.49Å; K25-Y143 HydrophobicContact CG-CE2 4.41Å; K25-Y143 PolarHBondContact N-OH 3.28Å
26E90.8Very high93Very high168 Ų16845 Ų4579%0.78524%0.239SC*.Hα-helixtrans-56.8-36.7-179.2-66.7-176.2175.200113A28 I29 A30E26-A28 VanDerWaalsContact C-N 3.31Å; E26-A28 PolarHBondContact O-N 3.42Å; E26-I29 PolarHBondContact O-N 2.97Å; E26-A30 WeakPolarHBondContact O-CB 3.36Å; E26-A30 PolarHBondContact O-N 2.98Å
27E93.6Very high92.9Very high136 Ų13651.6 Ų51.664%0.63626%0.264SS*.Hα-helixtrans-59.4-40.5175.1-63.9176.1-178.700112.5K25 W31 P141K25-E27 PolarHBondContact O-N 3.12Å; E27-W31 VanDerWaalsContact O-CB 3.27Å; E27-W31 WeakPolarHBondContact O-CB 3.48Å; E27-W31 PolarHBondContact O-N 3.34Å; E27-P141 HydrophobicContact CB-CB 4.49Å
28A92.7Very high92.9Very high5 Ų553.5 Ų53.54%0.04128%0.275CS..Hα-helixtrans-69.1-39.9178.800000111T24 K25 E26 L32 V140 P141 Y143T24-A28 HydrophobicContact CG2-CB 4.14Å; K25-A28 HydrophobicContact CB-CB 4.5Å; K25-A28 WeakPolarHBondContact O-CB 3.27Å; K25-A28 PolarHBondContact O-N 3.3Å; E26-A28 VanDerWaalsContact C-N 3.31Å; E26-A28 PolarHBondContact O-N 3.42Å; A28-L32 WeakPolarHBondContact O-CB 3.31Å; A28-L32 PolarHBondContact O-N 3.48Å; A28-V140 HydrophobicContact CB-CG1 4.32Å; A28-P141 VanDerWaalsContact CB-O 3.31Å; A28-P141 WeakPolarHBondContact CB-O 3.38Å; A28-Y143 HydrophobicContact CB-CD2 4.19Å; A28-Y143 HydrophobicContact CB-CE2 3.9Å
29I93.3Very high92.6Very high21 Ų2157.1 Ų57.111%0.10830%0.299CS..Hα-helixtrans-63.2-53.4176-61.2175.6000109.5L20 T24 K25 E26 W31 L32 L33 F67L20-I29 HydrophobicContact CD1-CG1 3.93Å; T24-I29 HydrophobicContact CG2-CD1 4.24Å; T24-I29 HydrophobicContact CG2-CG1 3.7Å; K25-I29 PolarHBondContact O-N 3.21Å; E26-I29 PolarHBondContact O-N 2.97Å; I29-W31 VanDerWaalsContact C-N 3.3Å; I29-W31 PolarHBondContact O-N 2.84Å; I29-L32 PolarHBondContact O-N 3.3Å; I29-L33 HydrophobicContact CG2-CD1 3.8Å; I29-L33 HydrophobicContact CG2-CG 4.19Å; I29-L33 WeakPolarHBondContact O-CB 3.26Å; I29-L33 VanDerWaalsContact O-CG 3.25Å; I29-L33 WeakPolarHBondContact O-CG 3.45Å; I29-L33 PolarHBondContact O-N 2.74Å; I29-F67 HydrophobicContact CD1-CZ 4.47Å; I29-F67 HydrophobicContact CG2-CE1 3.94Å; I29-F67 HydrophobicContact CG2-CE2 4.29Å; I29-F67 HydrophobicContact CG2-CZ 3.47Å; I29-F67 VanDerWaalsContact CG2-CZ 3.47Å
30A94.2Very high92.2Very high59 Ų5959.5 Ų59.549%0.48831%0.31SS..Hα-helixtrans-58.8-42-179.400000111.9E26 S34E26-A30 WeakPolarHBondContact O-CB 3.36Å; E26-A30 PolarHBondContact O-N 2.98Å; A30-S34 VanDerWaalsContact O-CB 3.26Å; A30-S34 WeakPolarHBondContact O-CB 3.3Å; A30-S34 PolarHBondContact O-N 2.86Å
31W94.7Very high91.7Very high35 Ų3568.7 Ų68.713%0.13335%0.353CS..Hα-helixtrans-62.6-48174.7170.579.5000112.5E27 I29 L33 S34 R35 E137 V140 P141 L148 I154E27-W31 VanDerWaalsContact O-CB 3.27Å; E27-W31 WeakPolarHBondContact O-CB 3.48Å; E27-W31 PolarHBondContact O-N 3.34Å; I29-W31 VanDerWaalsContact C-N 3.3Å; I29-W31 PolarHBondContact O-N 2.84Å; W31-L33 PolarHBondContact O-N 3.47Å; W31-S34 WeakPolarHBondContact O-CB 3.45Å; W31-S34 PolarHBondContact O-N 3.39Å; W31-R35 HydrophobicContact CD2-CG 4.45Å; W31-R35 HydrophobicContact CZ2-CG 4.33Å; W31-R35 WeakPolarHBondContact O-CG 3.47Å; W31-R35 PolarHBondContact O-N 2.97Å; W31-E137 HydrophobicContact CZ2-CG 4.12Å; W31-E137 PolarHBondContact NE1-OE1 3.21Å; W31-E137 VanDerWaalsContact NE1-OE1 3.12Å; W31-V140 HydrophobicContact CE3-CG1 4.32Å; W31-V140 HydrophobicContact CZ3-CG1 4.02Å; W31-V140 HydrophobicContact CZ3-CG2 4.41Å; W31-P141 HydrophobicContact CB-CB 4.45Å; W31-P141 HydrophobicContact CB-CG 3.84Å; W31-P141 HydrophobicContact CD2-CG 3.86Å; W31-P141 HydrophobicContact CE3-CG 4.41Å; W31-P141 HydrophobicContact CG-CG 3.58Å; W31-L148 HydrophobicContact CH2-CD1 3.78Å; W31-L148 HydrophobicContact CZ2-CD1 4.02Å; W31-I154 HydrophobicContact CH2-CB 4.49Å; W31-I154 HydrophobicContact CH2-CD1 3.87Å; W31-I154 HydrophobicContact CH2-CG1 4.17Å; W31-I154 HydrophobicContact CH2-CG2 3.56Å; W31-I154 HydrophobicContact CZ2-CD1 3.91Å; W31-I154 HydrophobicContact CZ3-CG2 3.86Å
32L94.3Very high91.4Very high6 Ų668.9 Ų68.93%0.03136%0.364CS..Hα-helixtrans-61.4-47.5179.3178.160.8000111.1L20 A28 I29 S34 R35 I36 I154 I155 L158L20-L32 HydrophobicContact CD1-CD2 4.27Å; L20-L32 HydrophobicContact CD2-CD2 4.09Å; A28-L32 WeakPolarHBondContact O-CB 3.31Å; A28-L32 PolarHBondContact O-N 3.48Å; I29-L32 PolarHBondContact O-N 3.3Å; L32-S34 VanDerWaalsContact C-N 3.3Å; L32-S34 PolarHBondContact O-N 3.21Å; L32-R35 PolarHBondContact O-N 3.29Å; L32-I36 HydrophobicContact CD1-CD1 3.99Å; L32-I36 HydrophobicContact CD1-CG1 4.29Å; L32-I36 HydrophobicContact CG-CD1 3.9Å; L32-I36 VanDerWaalsContact O-CG1 3.3Å; L32-I36 WeakPolarHBondContact O-CG1 3.35Å; L32-I36 PolarHBondContact O-N 3.14Å; L32-I154 HydrophobicContact CD1-CG2 4.23Å; L32-I155 HydrophobicContact CD1-CD1 4.47Å; L32-L158 HydrophobicContact CD1-CD1 3.82Å; L32-L158 HydrophobicContact CD2-CD1 3.84Å; L32-L158 HydrophobicContact CG-CD1 4.41Å
33L94.1Very high91.2Very high27 Ų2766.2 Ų66.214%0.14135%0.347CS..Hα-helixtrans-61.4-39.7177.7-66.5-179.3000111.7I29 W31 I36 R37 V49 F67I29-L33 HydrophobicContact CG2-CD1 3.8Å; I29-L33 HydrophobicContact CG2-CG 4.19Å; I29-L33 WeakPolarHBondContact O-CB 3.26Å; I29-L33 VanDerWaalsContact O-CG 3.25Å; I29-L33 WeakPolarHBondContact O-CG 3.45Å; I29-L33 PolarHBondContact O-N 2.74Å; W31-L33 PolarHBondContact O-N 3.47Å; L33-I36 PolarHBondContact O-N 2.9Å; L33-R37 WeakPolarHBondContact O-CB 3.39Å; L33-R37 VanDerWaalsContact O-CG 3.3Å; L33-R37 WeakPolarHBondContact O-CG 3.36Å; L33-R37 PolarHBondContact O-N 3.12Å; L33-V49 HydrophobicContact CD2-CB 4.06Å; L33-V49 HydrophobicContact CD2-CG1 3.36Å; L33-F67 HydrophobicContact CD1-CD1 4.25Å; L33-F67 HydrophobicContact CD1-CE1 3.9Å; L33-F67 HydrophobicContact CD2-CD1 3.85Å; L33-F67 HydrophobicContact CD2-CE1 4.25Å; L33-F67 HydrophobicContact CD2-CG 4.33Å
34S94.1Very high91.2Very high63 Ų6361.1 Ų61.144%0.44132%0.322SS..Hα-helixtrans-59.8-51173.5176.90000110.8A30 W31 L32 I36 R37 T38A30-S34 VanDerWaalsContact O-CB 3.26Å; A30-S34 WeakPolarHBondContact O-CB 3.3Å; A30-S34 PolarHBondContact O-N 2.86Å; W31-S34 WeakPolarHBondContact O-CB 3.45Å; W31-S34 PolarHBondContact O-N 3.39Å; L32-S34 VanDerWaalsContact C-N 3.3Å; L32-S34 PolarHBondContact O-N 3.21Å; S34-I36 VanDerWaalsContact C-N 3.28Å; S34-I36 PolarHBondContact O-N 2.95Å; S34-R37 PolarHBondContact O-N 3.36Å; S34-R37 VanDerWaalsContact O-N 3.16Å; S34-T38 WeakPolarHBondContact O-CB 3.23Å; S34-T38 PolarHBondContact O-N 3.21Å; S34-T38 PolarHBondContact O-OG1 3.23Å
35R94.3Very high91.3Very high25 Ų2560.7 Ų60.79%0.09432%0.319CS..Hα-helixtrans-60.9-34.2179.3-68.9-60.1-56.6-105.4-2.6113.3W31 L32 G43 G44 A45 L132 R133 E137 I154W31-R35 HydrophobicContact CD2-CG 4.45Å; W31-R35 HydrophobicContact CZ2-CG 4.33Å; W31-R35 WeakPolarHBondContact O-CG 3.47Å; W31-R35 PolarHBondContact O-N 2.97Å; L32-R35 PolarHBondContact O-N 3.29Å; R35-G43 PolarHBondContact NH2-O 2.86Å; R35-G44 WeakPolarHBondContact O-CA 3.36Å; R35-A45 PolarHBondContact O-N 3.36Å; R35-L132 HydrophobicContact CB-CD2 4.1Å; R35-R133 PolarHBondContact NH2-O 3.03Å; R35-E137 IonicContact CZ-OE1 2.79Å; R35-E137 IonicContact NH1-OE1 3.38Å; R35-E137 PolarHBondContact NH1-OE1 2.89Å; R35-E137 IonicContact NH1-OE2 3.88Å; R35-E137 PolarHBondContact NH1-OE2 3.25Å; R35-I154 HydrophobicContact CG-CD1 4.5Å
36I95Very high91.4Very high0 Ų056.5 Ų56.50%031%0.308CS..Hα-helixtrans-72.1-40.5177.2-62.8166.6000111.1L18 L32 L33 S34 G46 L47 V49 L129 L132L18-I36 HydrophobicContact CD1-CD1 3.8Å; L32-I36 HydrophobicContact CD1-CD1 3.99Å; L32-I36 HydrophobicContact CD1-CG1 4.29Å; L32-I36 HydrophobicContact CG-CD1 3.9Å; L32-I36 VanDerWaalsContact O-CG1 3.3Å; L32-I36 WeakPolarHBondContact O-CG1 3.35Å; L32-I36 PolarHBondContact O-N 3.14Å; L33-I36 PolarHBondContact O-N 2.9Å; S34-I36 VanDerWaalsContact C-N 3.28Å; S34-I36 PolarHBondContact O-N 2.95Å; I36-G46 PolarHBondContact O-N 3.32Å; I36-G46 VanDerWaalsContact O-N 3.09Å; I36-L47 HydrophobicContact CG2-CB 3.7Å; I36-L47 HydrophobicContact CG2-CD1 4.17Å; I36-L47 HydrophobicContact CG2-CG 4.44Å; I36-L47 PolarHBondContact O-N 2.89Å; I36-V49 HydrophobicContact CB-CG2 3.9Å; I36-V49 HydrophobicContact CD1-CG2 4.37Å; I36-V49 HydrophobicContact CG2-CG2 3.23Å; I36-L129 HydrophobicContact CD1-CD2 4.07Å; I36-L129 HydrophobicContact CG1-CD2 3.94Å; I36-L129 HydrophobicContact CG2-CD2 4.11Å; I36-L132 HydrophobicContact CG1-CD2 4.5Å
37R95.2Very high91.6Very high139 Ų13948.8 Ų48.853%0.52527%0.271SS..Hα-helixtrans-76.2-32-179.1-70.1173.5-179.9178.1-0.8114L33 S34 L47 V49L33-R37 WeakPolarHBondContact O-CB 3.39Å; L33-R37 VanDerWaalsContact O-CG 3.3Å; L33-R37 WeakPolarHBondContact O-CG 3.36Å; L33-R37 PolarHBondContact O-N 3.12Å; S34-R37 PolarHBondContact O-N 3.36Å; S34-R37 VanDerWaalsContact O-N 3.16Å; R37-L47 WeakPolarHBondContact CA-O 3.13Å; R37-V49 PolarHBondContact NE-O 3.41Å; R37-V49 PolarHBondContact NH2-O 2.93Å
38T93.9Very high91.6Very high40 Ų4045.7 Ų45.725%0.24526%0.259CS..SBendtrans-57.7137.9-178.9-65.30000110.9S34 A42 G44 A45 G46S34-T38 WeakPolarHBondContact O-CB 3.23Å; S34-T38 PolarHBondContact O-N 3.21Å; S34-T38 PolarHBondContact O-OG1 3.23Å; T38-A42 HydrophobicContact CG2-CB 3.5Å; T38-G44 CarbonylContact O-C 3.58Å; T38-G44 WeakPolarHBondContact O-CA 3.24Å; T38-A45 PolarHBondContact O-N 2.75Å; T38-A45 VanDerWaalsContact O-N 3.13Å; T38-G46 WeakPolarHBondContact O-CA 3.11Å; T38-G46 PolarHBondContact O-N 3.44Å
39P90.2Very high91.7Very high80 Ų8045.7 Ų45.752%0.51926%0.258SS..  trans-59.8153178.1-24.934.2000113.7Q41 A42 G43 G44P39-Q41 PolarHBondContact O-N 2.82Å; P39-A42 PolarHBondContact O-N 2.81Å; P39-G43 PolarHBondContact O-N 2.79Å; P39-G44 PolarHBondContact O-N 3.3Å; P39-G44 VanDerWaalsContact O-N 3.1Å
40Q85.1Confident91.6Very high76 Ų7647.4 Ų47.436%0.35527%0.266SS..G310 helixtrans-54.9-38.2177.1-83-179.6-29.500112.9A42 G43 G44 R75 D82 E128Q40-A42 PolarHBondContact O-N 3.06Å; Q40-G43 WeakPolarHBondContact O-CA 3.32Å; Q40-G43 PolarHBondContact O-N 3.1Å; Q40-G44 WeakPolarHBondContact CA-O 3.4Å; Q40-R75 VanDerWaalsContact CD-NH2 3.29Å; Q40-D82 PolarHBondContact NE2-OD2 3.42Å; Q40-E128 PolarHBondContact NE2-OE1 2.73Å; Q40-E128 PolarHBondContact NE2-OE2 3.42Å
41Q84Confident91.3Very high198 Ų19850 Ų5093%0.92527%0.268SS*.G310 helixtrans-58.6-33.1177.9-64.7177-1.400112.9P39P39-Q41 PolarHBondContact O-N 2.82Å
42A85.9Confident90.8Very high63 Ų6349.3 Ų49.352%0.52127%0.267SS..G310 helixtrans-89.7-1.4175.800000112.7T38 P39 Q40 K135T38-A42 HydrophobicContact CG2-CB 3.5Å; P39-A42 PolarHBondContact O-N 2.81Å; Q40-A42 PolarHBondContact O-N 3.06Å; A42-K135 PolarHBondContact O-NZ 2.88Å
43G81.6Confident89.7Confident14 Ų1451 Ų5114%0.14429%0.285CS..THydrogen-bonded Turntrans90.119.5-179.700000115.8R35 P39 Q40 K135R35-G43 PolarHBondContact NH2-O 2.86Å; P39-G43 PolarHBondContact O-N 2.79Å; Q40-G43 WeakPolarHBondContact O-CA 3.32Å; Q40-G43 PolarHBondContact O-N 3.1Å; G43-K135 VanDerWaalsContact CA-NZ 3.27Å
44G88.6Confident88Confident8 Ų854.1 Ų54.18%0.08231%0.307CS..SBendtrans-98.3-165.8166.900000112.7R35 T38 P39 Q40R35-G44 WeakPolarHBondContact O-CA 3.36Å; T38-G44 CarbonylContact O-C 3.58Å; T38-G44 WeakPolarHBondContact O-CA 3.24Å; P39-G44 PolarHBondContact O-N 3.3Å; P39-G44 VanDerWaalsContact O-N 3.1Å; Q40-G44 WeakPolarHBondContact CA-O 3.4Å
45A90.1Very high86.3Confident1 Ų152.8 Ų52.81%0.00830%0.304CS..  trans-99.9-18178.400000113.9R35 T38 L47 R75 E128 L132R35-A45 PolarHBondContact O-N 3.36Å; T38-A45 PolarHBondContact O-N 2.75Å; T38-A45 VanDerWaalsContact O-N 3.13Å; A45-L47 VanDerWaalsContact C-N 3.29Å; A45-L47 HydrophobicContact CB-CD1 3.81Å; A45-L47 HydrophobicContact CB-CG 3.82Å; A45-L47 PolarHBondContact O-N 3.21Å; A45-R75 PolarHBondContact O-NE 3.02Å; A45-R75 PolarHBondContact O-NH2 3.28Å; A45-E128 HydrophobicContact CB-CB 4.5Å; A45-L132 HydrophobicContact CB-CD1 4.34Å
46G93.1Very high84.1Confident23 Ų2357.4 Ų57.424%0.23733%0.334CS..  trans63.931.6-176.200000113.6I36 T38I36-G46 PolarHBondContact O-N 3.32Å; I36-G46 VanDerWaalsContact O-N 3.09Å; T38-G46 WeakPolarHBondContact O-CA 3.11Å; T38-G46 PolarHBondContact O-N 3.44Å
47L95.4Very high82Confident5 Ų559.7 Ų59.73%0.02635%0.35CS..  trans-100.1158.5-178.1-60.3173.3000111.2I36 R37 A45 V69 A71 R75 I125 E128 L129I36-L47 HydrophobicContact CG2-CB 3.7Å; I36-L47 HydrophobicContact CG2-CD1 4.17Å; I36-L47 HydrophobicContact CG2-CG 4.44Å; I36-L47 PolarHBondContact O-N 2.89Å; R37-L47 WeakPolarHBondContact CA-O 3.13Å; A45-L47 VanDerWaalsContact C-N 3.29Å; A45-L47 HydrophobicContact CB-CD1 3.81Å; A45-L47 HydrophobicContact CB-CG 3.82Å; A45-L47 PolarHBondContact O-N 3.21Å; L47-V69 HydrophobicContact CB-CG1 4.19Å; L47-V69 HydrophobicContact CD1-CG1 4.05Å; L47-A71 HydrophobicContact CD2-CB 3.84Å; L47-R75 HydrophobicContact CD2-CG 4.42Å; L47-I125 HydrophobicContact CD1-CG2 4.19Å; L47-I125 HydrophobicContact CD2-CG1 4.24Å; L47-E128 HydrophobicContact CD1-CB 4.23Å; L47-L129 HydrophobicContact CD1-CD2 3.91Å; L47-L129 HydrophobicContact CD1-CG 3.96Å
48L94.8Very high79.7Confident72 Ų7256 Ų5638%0.37735%0.35SS..EExtended strand (participates in β ladder)trans-90.1133.5175.4-57.2176.1000109.1F12 V69 G70F12-L48 HydrophobicContact CB-CD1 3.74Å; F12-L48 HydrophobicContact CD1-CB 3.68Å; F12-L48 HydrophobicContact CD1-CD1 4.06Å; F12-L48 HydrophobicContact CD1-CG 4.49Å; F12-L48 HydrophobicContact CD2-CB 4.25Å; F12-L48 HydrophobicContact CE1-CB 3.71Å; F12-L48 HydrophobicContact CE2-CB 4.32Å; F12-L48 HydrophobicContact CG-CB 3.96Å; F12-L48 HydrophobicContact CG-CD1 3.88Å; F12-L48 HydrophobicContact CZ-CB 4.05Å; L48-V69 WeakPolarHBondContact O-CA 3.3Å; L48-G70 PolarHBondContact N-O 3.28Å; L48-G70 PolarHBondContact O-N 3.27Å
49V93.9Very high77.6Confident4 Ų458.9 Ų58.92%0.02436%0.36CS..EExtended strand (participates in β ladder)trans-139.7131.3179.7-169.20000111L33 I36 R37 F67 L68 V69L33-V49 HydrophobicContact CD2-CB 4.06Å; L33-V49 HydrophobicContact CD2-CG1 3.36Å; I36-V49 HydrophobicContact CB-CG2 3.9Å; I36-V49 HydrophobicContact CD1-CG2 4.37Å; I36-V49 HydrophobicContact CG2-CG2 3.23Å; R37-V49 PolarHBondContact NE-O 3.41Å; R37-V49 PolarHBondContact NH2-O 2.93Å; V49-F67 HydrophobicContact CG1-CB 4.01Å; V49-L68 VanDerWaalsContact CA-O 3.27Å; V49-L68 WeakPolarHBondContact CA-O 3.44Å; V49-L68 WeakPolarHBondContact CG1-O 3.43Å; V49-V69 HydrophobicContact CG1-CG2 4.23Å; V49-V69 HydrophobicContact CG2-CG1 4.3Å; V49-V69 HydrophobicContact CG2-CG2 4.15Å
50E91Very high75.6Confident58 Ų5865 Ų6527%0.27138%0.382SS..EExtended strand (participates in β ladder)trans-129.6143.9175.5-83.9172.5-173.300110.7P10 S11 F12 F67 L68P10-E50 WeakPolarHBondContact CA-OE2 3.07Å; S11-E50 WeakPolarHBondContact CB-OE1 3.15Å; S11-E50 PolarHBondContact N-OE2 2.8Å; S11-E50 PolarHBondContact OG-OE1 2.88Å; F12-E50 HydrophobicContact CE1-CB 4.03Å; F12-E50 HydrophobicContact CE1-CG 3.73Å; F12-E50 HydrophobicContact CZ-CB 4.3Å; F12-E50 HydrophobicContact CZ-CG 4.48Å; E50-F67 CarbonylContact O-C 3.38Å; E50-F67 WeakPolarHBondContact O-CA 3.43Å; E50-L68 PolarHBondContact N-O 3.18Å; E50-L68 PolarHBondContact O-N 3.41Å
51Q88.8Confident74Confident112 Ų11270.7 Ų70.752%0.52341%0.405SS..EExtended strand (participates in β ladder)trans-76.3137.3170-171.4173.110.400109G53 P64 F67Q51-G53 PolarHBondContact O-N 3.13Å; Q51-P64 PolarHBondContact NE2-O 3.34Å; Q51-F67 HydrophobicContact CB-CD1 3.9Å; Q51-F67 HydrophobicContact CB-CE1 3.78Å; Q51-F67 HydrophobicContact CG-CD1 4.14Å; Q51-F67 HydrophobicContact CG-CE1 3.77Å; Q51-F67 HydrophobicContact CG-CZ 4.35Å
52L84.1Confident73.2Confident22 Ų2264.6 Ų64.612%0.11538%0.379CS..PPolyproline II helixtrans-64.9122.5176.4-172.870.1000109.7L66 L68 A478 V481L52-L66 HydrophobicContact CB-CB 4.01Å; L52-L66 WeakPolarHBondContact CB-O 3.43Å; L52-L66 HydrophobicContact CD2-CB 4.12Å; L52-L66 HydrophobicContact CD2-CD1 4.01Å; L52-L66 PolarHBondContact N-O 2.89Å; L52-L68 HydrophobicContact CD1-CD1 3.84Å; L52-L68 HydrophobicContact CD1-CD2 4.29Å; L52-L68 HydrophobicContact CD1-CG 4.2Å; L52-A478 HydrophobicContact CD1-CB 3.95Å; L52-A478 HydrophobicContact CD2-CB 4.16Å; L52-A478 HydrophobicContact CG-CB 4.12Å; L52-V481 HydrophobicContact CD1-CG2 4.38Å; L52-V481 HydrophobicContact CD2-CB 4.05Å; L52-V481 HydrophobicContact CD2-CG1 3.91Å
53G69.8Low72.6Confident40 Ų4062.6 Ų62.641%0.41236%0.36SS..PPolyproline II helixtrans-58.9160.1175.200000112.2Q51 G55Q51-G53 PolarHBondContact O-N 3.13Å; G53-G55 PolarHBondContact O-N 2.87Å
54P59.8Low72.4Confident94 Ų9465.4 Ų65.461%0.6138%0.375SS*.  trans-59.1-9.5-172.918-28.9000115.4A58 R482P54-A58 HydrophobicContact CB-CB 3.89Å; P54-A58 WeakPolarHBondContact O-CB 3.46Å; P54-A58 PolarHBondContact O-N 3.22Å; P54-R482 PolarHBondContact O-NH2 2.84Å
55G57.1Low72.4Confident35 Ų3565.7 Ų65.736%0.36138%0.375SS..  trans67171.4-174.100000111.3G53 S57G53-G55 PolarHBondContact O-N 2.87Å; G55-S57 PolarHBondContact O-N 3.28Å
56V49.3Very low72.5Confident121 Ų12165.9 Ų65.973%0.73338%0.376SS*.THydrogen-bonded Turntrans-65.6-5.1-179.1-172.20000112.3P476V56-P476 HydrophobicContact CG2-CG 4.25Å
57S51.3Low72.5Confident48 Ų4865 Ų6534%0.33637%0.365SS..THydrogen-bonded Turntrans-156.670.9-177.5-72.10000111.7G55 E59G55-S57 PolarHBondContact O-N 3.28Å; S57-E59 PolarHBondContact O-N 2.83Å
58A45.1Very low72.5Confident63 Ų6365 Ų6552%0.52137%0.365SS..  trans-669916200000109.1P54P54-A58 HydrophobicContact CB-CB 3.89Å; P54-A58 WeakPolarHBondContact O-CB 3.46Å; P54-A58 PolarHBondContact O-N 3.22Å
59E51.1Low72.5Confident99 Ų9961.6 Ų61.646%0.46335%0.347SS..  trans-73.7141.7159.9-72.3176.7-160.900107.4S57 K61 D62 K467S57-E59 PolarHBondContact O-N 2.83Å; E59-K61 PolarHBondContact O-N 3.01Å; E59-D62 PolarHBondContact O-N 3.23Å; E59-K467 IonicContact OE1-NZ 3.43Å; E59-K467 PolarHBondContact OE1-NZ 3.46Å
60H46.8Very low72.6Confident210 Ų21061.4 Ų61.497%0.97235%0.346SS*.THydrogen-bonded Turntrans-57.82.5-179.2-77.8-62.2000115.6
61K52.9Low72.7Confident195 Ų19559.4 Ų59.485%0.84834%0.34SS*.THydrogen-bonded Turntrans-106.2-8.7-178.5-73.4-173.6175.2-176.10114.6E59E59-K61 PolarHBondContact O-N 3.01Å
62D65.9Low72.9Confident69 Ų6956.9 Ų56.937%0.36933%0.334SS..SBendtrans-84.9139.2-176.3-66.8-14000110.9E59 P64 R482E59-D62 PolarHBondContact O-N 3.23Å; D62-P64 WeakPolarHBondContact O-CD 3.44Å; D62-R482 IonicContact OD2-CZ 3.72Å; D62-R482 IonicContact OD2-NH1 3.84Å; D62-R482 PolarHBondContact OD2-NH1 3.41Å
63N74.6Confident73.2Confident22 Ų2258.4 Ų58.412%0.11834%0.339CS..  trans-61.9119179.2-177.22.4000110.3E19 L20 S22 N65E19-N63 PolarHBondContact OE1-ND2 3.37Å; L20-N63 PolarHBondContact O-ND2 2.96Å; S22-N63 WeakPolarHBondContact CA-OD1 3.46Å; S22-N63 PolarHBondContact OG-OD1 3.11Å; N63-N65 VanDerWaalsContact C-N 3.26Å; N63-N65 PolarHBondContact O-N 3.37Å; N63-N65 PolarHBondContact OD1-N 3.05Å
64P78Confident74.1Confident73 Ų7364.1 Ų64.147%0.47436%0.355SS..SBendtrans-76.4-12.5-178.931.3-35.2000113.3Q51 D62 L66Q51-P64 PolarHBondContact NE2-O 3.34Å; D62-P64 WeakPolarHBondContact O-CD 3.44Å; P64-L66 PolarHBondContact O-N 3.49Å
65N88.3Confident75.6Confident13 Ų1360.8 Ų60.87%0.0733%0.33CS..  trans-97.353.4-168.3-61.5-22.8000112.7L20 I21 S22 N63 F67L20-N65 HydrophobicContact CB-CB 3.97Å; L20-N65 PolarHBondContact N-O 2.89Å; I21-N65 PolarHBondContact O-ND2 2.97Å; S22-N65 PolarHBondContact O-ND2 3.42Å; N63-N65 VanDerWaalsContact C-N 3.26Å; N63-N65 PolarHBondContact O-N 3.37Å; N63-N65 PolarHBondContact OD1-N 3.05Å; N65-F67 HydrophobicContact CB-CE2 4.1Å
66L90.9Very high77.4Confident6 Ų659.5 Ų59.53%0.03132%0.315CS..EExtended strand (participates in β ladder)trans-103.2124.5172-74.3161.9000109.8V17 E19 L52 P64 V481 R482V17-L66 HydrophobicContact CG1-CD2 3.91Å; E19-L66 HydrophobicContact CB-CD2 3.77Å; E19-L66 HydrophobicContact CG-CD2 3.73Å; E19-L66 HydrophobicContact CG-CG 4.48Å; L52-L66 HydrophobicContact CB-CB 4.01Å; L52-L66 WeakPolarHBondContact CB-O 3.43Å; L52-L66 HydrophobicContact CD2-CB 4.12Å; L52-L66 HydrophobicContact CD2-CD1 4.01Å; L52-L66 PolarHBondContact N-O 2.89Å; P64-L66 PolarHBondContact O-N 3.49Å; L66-V481 HydrophobicContact CD2-CG1 4.48Å; L66-R482 HydrophobicContact CD1-CG 4.08Å
67F93.6Very high79.5Confident4 Ų454.1 Ų54.12%0.01828%0.282CS..EExtended strand (participates in β ladder)trans-120.1132.6-179.1-57.9-87.4000110.7V17 L18 L20 I29 L33 V49 E50 Q51 N65V17-F67 CarbonylContact C-O 3.59Å; V17-F67 WeakPolarHBondContact CA-O 3.3Å; L18-F67 HydrophobicContact CB-CB 4.33Å; L18-F67 PolarHBondContact N-O 3.21Å; L18-F67 PolarHBondContact O-N 2.98Å; L20-F67 HydrophobicContact CD1-CD2 4.13Å; L20-F67 HydrophobicContact CD1-CE2 3.61Å; L20-F67 HydrophobicContact CD1-CZ 4.46Å; L20-F67 HydrophobicContact CG-CD2 4.35Å; L20-F67 HydrophobicContact CG-CE2 4.14Å; I29-F67 HydrophobicContact CD1-CZ 4.47Å; I29-F67 HydrophobicContact CG2-CE1 3.94Å; I29-F67 HydrophobicContact CG2-CE2 4.29Å; I29-F67 HydrophobicContact CG2-CZ 3.47Å; I29-F67 VanDerWaalsContact CG2-CZ 3.47Å; L33-F67 HydrophobicContact CD1-CD1 4.25Å; L33-F67 HydrophobicContact CD1-CE1 3.9Å; L33-F67 HydrophobicContact CD2-CD1 3.85Å; L33-F67 HydrophobicContact CD2-CE1 4.25Å; L33-F67 HydrophobicContact CD2-CG 4.33Å; V49-F67 HydrophobicContact CG1-CB 4.01Å; E50-F67 CarbonylContact O-C 3.38Å; E50-F67 WeakPolarHBondContact O-CA 3.43Å; Q51-F67 HydrophobicContact CB-CD1 3.9Å; Q51-F67 HydrophobicContact CB-CE1 3.78Å; Q51-F67 HydrophobicContact CG-CD1 4.14Å; Q51-F67 HydrophobicContact CG-CE1 3.77Å; Q51-F67 HydrophobicContact CG-CZ 4.35Å; N65-F67 HydrophobicContact CB-CE2 4.1Å
68L94.8Very high81.4Confident5 Ų553.7 Ų53.73%0.02628%0.279CS..EExtended strand (participates in β ladder)trans-92.3132175.1-56.9179.5000108.9P10 P14 V17 V49 E50 L52 L170 L477 V481P10-L68 HydrophobicContact CB-CD1 4.5Å; P14-L68 HydrophobicContact CB-CB 4.05Å; P14-L68 HydrophobicContact CB-CD1 4.07Å; P14-L68 HydrophobicContact CB-CD2 4.31Å; P14-L68 HydrophobicContact CB-CG 4.37Å; V17-L68 HydrophobicContact CG2-CD2 4.02Å; V49-L68 VanDerWaalsContact CA-O 3.27Å; V49-L68 WeakPolarHBondContact CA-O 3.44Å; V49-L68 WeakPolarHBondContact CG1-O 3.43Å; E50-L68 PolarHBondContact N-O 3.18Å; E50-L68 PolarHBondContact O-N 3.41Å; L52-L68 HydrophobicContact CD1-CD1 3.84Å; L52-L68 HydrophobicContact CD1-CD2 4.29Å; L52-L68 HydrophobicContact CD1-CG 4.2Å; L68-L170 HydrophobicContact CD2-CD1 4.49Å; L68-L477 HydrophobicContact CD1-CD2 3.92Å; L68-V481 HydrophobicContact CD2-CG1 4.45Å; L68-V481 HydrophobicContact CD2-CG2 3.86Å
69V96.2Very high83.6Confident0 Ų050.7 Ų50.70%025%0.254CS..EExtended strand (participates in β ladder)trans-119.2135.2179.1-173.70000109.7L15 V16 L18 L47 L48 V49 I125 L129L15-V69 PolarHBondContact N-O 2.93Å; V16-V69 HydrophobicContact CB-CB 4.33Å; V16-V69 PolarHBondContact N-O 3.45Å; V16-V69 VanDerWaalsContact N-O 3.08Å; V16-V69 PolarHBondContact O-N 2.96Å; L18-V69 HydrophobicContact CD1-CG2 3.67Å; L18-V69 HydrophobicContact CG-CG2 3.86Å; L47-V69 HydrophobicContact CB-CG1 4.19Å; L47-V69 HydrophobicContact CD1-CG1 4.05Å; L48-V69 WeakPolarHBondContact O-CA 3.3Å; V49-V69 HydrophobicContact CG1-CG2 4.23Å; V49-V69 HydrophobicContact CG2-CG1 4.3Å; V49-V69 HydrophobicContact CG2-CG2 4.15Å; V69-I125 HydrophobicContact CB-CG2 4.48Å; V69-I125 HydrophobicContact CG1-CG2 3.79Å; V69-L129 HydrophobicContact CG1-CD1 4.45Å
70G95.1Very high85.6Confident0 Ų046 Ų460%023%0.232CC..EExtended strand (participates in β ladder)trans-148.8-169.5175.700000110.5F12 L48F12-G70 VanDerWaalsContact CE2-CA 3.49Å; L48-G70 PolarHBondContact N-O 3.28Å; L48-G70 PolarHBondContact O-N 3.27Å
71A93.8Very high87.7Confident16 Ų1639.4 Ų39.413%0.13220%0.202CC..  trans-153.1158.1-179.500000110.1L47 R75 L76L47-A71 HydrophobicContact CD2-CB 3.84Å; A71-R75 HydrophobicContact CB-CB 4.29Å; A71-R75 HydrophobicContact CB-CG 4.17Å; A71-L76 HydrophobicContact CB-CD1 4.49Å; A71-L76 HydrophobicContact CB-CD2 3.87Å; A71-L76 HydrophobicContact CB-CG 3.81Å
72S92.4Very high89.4Confident59 Ų5933.2 Ų33.241%0.41318%0.178SC..  trans-68.9157.4164.864.60000110.3E74 R75 L76S72-E74 VanDerWaalsContact C-N 3.34Å; S72-E74 PolarHBondContact O-N 3.41Å; S72-R75 WeakPolarHBondContact O-CB 3.25Å; S72-R75 PolarHBondContact O-N 3.16Å; S72-R75 VanDerWaalsContact O-N 3.14Å; S72-R75 WeakPolarHBondContact OG-CB 3.45Å; S72-R75 PolarHBondContact OG-N 2.9Å; S72-L76 PolarHBondContact O-N 3.03Å
73W90.1Very high90.5Very high55 Ų5530.8 Ų30.821%0.20817%0.165CC..Hα-helixtrans-61-42.7-179.8-171.3-114.9000112.8R75 L76 L77 D111 G112 F115 L116W73-R75 PolarHBondContact O-N 3.02Å; W73-L76 HydrophobicContact CE3-CD1 3.87Å; W73-L76 HydrophobicContact CZ3-CD1 4.09Å; W73-L76 WeakPolarHBondContact O-CB 3.11Å; W73-L76 PolarHBondContact O-N 3.19Å; W73-L76 VanDerWaalsContact O-N 3.14Å; W73-L77 HydrophobicContact CZ2-CD2 3.95Å; W73-L77 WeakPolarHBondContact O-CG 3.44Å; W73-L77 PolarHBondContact O-N 3.32Å; W73-D111 PolarHBondContact NE1-O 2.57Å; W73-G112 WeakPolarHBondContact CZ2-O 3.36Å; W73-F115 HydrophobicContact CZ2-CB 4.18Å; W73-L116 HydrophobicContact CH2-CB 3.67Å; W73-L116 HydrophobicContact CH2-CD1 3.99Å; W73-L116 HydrophobicContact CH2-CG 3.8Å; W73-L116 HydrophobicContact CZ2-CD1 4.4Å; W73-L116 HydrophobicContact CZ2-CG 4.21Å; W73-L116 HydrophobicContact CZ3-CB 4.31Å; W73-L116 HydrophobicContact CZ3-CD1 4.4Å
74E89.6Confident91.2Very high160 Ų16030.9 Ų30.975%0.74817%0.172SC*.Hα-helixtrans-57.9-38.8175.2-62.7-178165.100112.3S72 L77 S78S72-E74 VanDerWaalsContact C-N 3.34Å; S72-E74 PolarHBondContact O-N 3.41Å; E74-L77 PolarHBondContact O-N 3.16Å; E74-S78 PolarHBondContact O-N 3.46Å
75R91.9Very high91.8Very high23 Ų2328.2 Ų28.29%0.08715%0.154CC..Hα-helixtrans-69-38178.4178.660.2-175.6101.2-3.4112.2Q40 A45 L47 A71 S72 W73 S78 G79 E128Q40-R75 VanDerWaalsContact CD-NH2 3.29Å; A45-R75 PolarHBondContact O-NE 3.02Å; A45-R75 PolarHBondContact O-NH2 3.28Å; L47-R75 HydrophobicContact CD2-CG 4.42Å; A71-R75 HydrophobicContact CB-CB 4.29Å; A71-R75 HydrophobicContact CB-CG 4.17Å; S72-R75 WeakPolarHBondContact O-CB 3.25Å; S72-R75 PolarHBondContact O-N 3.16Å; S72-R75 VanDerWaalsContact O-N 3.14Å; S72-R75 WeakPolarHBondContact OG-CB 3.45Å; S72-R75 PolarHBondContact OG-N 2.9Å; W73-R75 PolarHBondContact O-N 3.02Å; R75-S78 PolarHBondContact O-N 2.95Å; R75-G79 PolarHBondContact O-N 3.25Å; R75-E128 IonicContact CZ-OE1 3.12Å; R75-E128 IonicContact CZ-OE2 2.9Å; R75-E128 IonicContact NH1-OE1 2.75Å; R75-E128 PolarHBondContact NH1-OE1 2.98Å; R75-E128 IonicContact NH2-OE1 2.83Å; R75-E128 PolarHBondContact NH2-OE1 3.42Å; R75-E128 IonicContact NH2-OE2 3.68Å; R75-E128 PolarHBondContact NH2-OE2 3.49Å
76L93.4Very high91.9Very high9 Ų929.7 Ų29.75%0.04716%0.159CC..Hα-helixtrans-65-41.4174.3-69.8170.3000111.4A71 S72 W73 G79 A80 L116 C121 I124 I125A71-L76 HydrophobicContact CB-CD1 4.49Å; A71-L76 HydrophobicContact CB-CD2 3.87Å; A71-L76 HydrophobicContact CB-CG 3.81Å; S72-L76 PolarHBondContact O-N 3.03Å; W73-L76 HydrophobicContact CE3-CD1 3.87Å; W73-L76 HydrophobicContact CZ3-CD1 4.09Å; W73-L76 WeakPolarHBondContact O-CB 3.11Å; W73-L76 PolarHBondContact O-N 3.19Å; W73-L76 VanDerWaalsContact O-N 3.14Å; L76-G79 PolarHBondContact O-N 3.18Å; L76-A80 WeakPolarHBondContact O-CB 3.22Å; L76-A80 PolarHBondContact O-N 3.14Å; L76-L116 HydrophobicContact CB-CD1 3.98Å; L76-C121 HydrophobicContact CD1-CB 4.33Å; L76-C121 HydrophobicContact CD2-CB 4.17Å; L76-I124 HydrophobicContact CD2-CG2 4.33Å; L76-I125 HydrophobicContact CD2-CD1 4.42Å; L76-I125 HydrophobicContact CD2-CG1 4.25Å
77L93.1Very high92Very high8 Ų830.8 Ų30.84%0.04216%0.164CC..Hα-helixtrans-63.7-43.8174.8-64.1178.1000111.6W73 E74 G79 A80 E81 F97 F108 F115 L116W73-L77 HydrophobicContact CZ2-CD2 3.95Å; W73-L77 WeakPolarHBondContact O-CG 3.44Å; W73-L77 PolarHBondContact O-N 3.32Å; E74-L77 PolarHBondContact O-N 3.16Å; L77-G79 VanDerWaalsContact C-N 3.32Å; L77-G79 PolarHBondContact O-N 3.42Å; L77-A80 WeakPolarHBondContact O-CB 3.11Å; L77-A80 PolarHBondContact O-N 3.22Å; L77-E81 PolarHBondContact O-N 3.13Å; L77-E81 VanDerWaalsContact O-N 3.14Å; L77-F97 HydrophobicContact CB-CE1 4.18Å; L77-F97 HydrophobicContact CB-CZ 4.24Å; L77-F97 HydrophobicContact CD2-CE1 4.29Å; L77-F97 HydrophobicContact CD2-CZ 3.79Å; L77-F97 HydrophobicContact CG-CZ 4.49Å; L77-F97 WeakPolarHBondContact O-CE1 3.34Å; L77-F108 HydrophobicContact CD1-CE2 4.2Å; L77-F108 HydrophobicContact CD2-CE2 4.36Å; L77-F115 HydrophobicContact CD2-CD1 4.14Å; L77-L116 HydrophobicContact CD2-CD1 4.18Å; L77-L116 HydrophobicContact CD2-CG 4.44Å
78S92Very high91.9Very high39 Ų3933.2 Ų33.227%0.27318%0.176SC..Hα-helixtrans-59.9-43.7173.7-172.20000111.6E74 R75 A80 E81 D82E74-S78 PolarHBondContact O-N 3.46Å; R75-S78 PolarHBondContact O-N 2.95Å; S78-A80 VanDerWaalsContact C-N 3.32Å; S78-A80 PolarHBondContact O-N 2.82Å; S78-E81 WeakPolarHBondContact O-CB 3.32Å; S78-E81 PolarHBondContact O-N 2.98Å; S78-D82 PolarHBondContact O-N 3.44Å
79G91.9Very high91.7Very high0 Ų034.6 Ų34.60%018%0.18CC..Hα-helixtrans-67-31.3177.100000113.2R75 L76 L77 E81 D82 V83R75-G79 PolarHBondContact O-N 3.25Å; L76-G79 PolarHBondContact O-N 3.18Å; L77-G79 VanDerWaalsContact C-N 3.32Å; L77-G79 PolarHBondContact O-N 3.42Å; G79-E81 VanDerWaalsContact C-N 3.31Å; G79-E81 PolarHBondContact O-N 2.64Å; G79-D82 PolarHBondContact O-N 3.03Å; G79-V83 WeakPolarHBondContact O-CB 3.42Å; G79-V83 VanDerWaalsContact O-CG2 3.25Å; G79-V83 WeakPolarHBondContact O-CG2 3.37Å; G79-V83 PolarHBondContact O-N 3.46Å
80A92.2Very high91.4Very high0 Ų038.7 Ų38.70%021%0.209CC..Hα-helixtrans-64.7-35.3173.100000112.3L76 L77 S78 G84 L85 F97 L116 I124L76-A80 WeakPolarHBondContact O-CB 3.22Å; L76-A80 PolarHBondContact O-N 3.14Å; L77-A80 WeakPolarHBondContact O-CB 3.11Å; L77-A80 PolarHBondContact O-N 3.22Å; S78-A80 VanDerWaalsContact C-N 3.32Å; S78-A80 PolarHBondContact O-N 2.82Å; A80-G84 PolarHBondContact O-N 2.84Å; A80-G84 VanDerWaalsContact O-N 3.14Å; A80-L85 HydrophobicContact CB-CD1 3.85Å; A80-L85 HydrophobicContact CB-CG 4.38Å; A80-L85 PolarHBondContact O-N 3.11Å; A80-F97 HydrophobicContact CB-CD1 3.82Å; A80-F97 HydrophobicContact CB-CE1 4.13Å; A80-L116 HydrophobicContact CB-CD1 4.28Å; A80-L116 HydrophobicContact CB-CD2 4.14Å; A80-I124 HydrophobicContact CB-CD1 3.83Å
81E92.1Very high91.1Very high71 Ų7143.4 Ų43.433%0.33223%0.234SC..Hα-helixtrans-70.2-44.1172.3178.5169.2-168.800111.4L77 S78 G79 V83 G84 F97 T98 C99L77-E81 PolarHBondContact O-N 3.13Å; L77-E81 VanDerWaalsContact O-N 3.14Å; S78-E81 WeakPolarHBondContact O-CB 3.32Å; S78-E81 PolarHBondContact O-N 2.98Å; G79-E81 VanDerWaalsContact C-N 3.31Å; G79-E81 PolarHBondContact O-N 2.64Å; E81-V83 VanDerWaalsContact C-N 3.34Å; E81-V83 PolarHBondContact O-N 3.43Å; E81-G84 WeakPolarHBondContact O-CA 3.39Å; E81-G84 PolarHBondContact O-N 3.37Å; E81-F97 HydrophobicContact CB-CD1 4.32Å; E81-T98 HydrophobicContact CG-CG2 4.44Å; E81-T98 WeakPolarHBondContact OE1-CB 3.41Å; E81-C99 WeakPolarHBondContact OE2-CB 3.33Å; E81-C99 PolarHBondContact OE2-N 2.88Å; E81-C99 PolarHBondContact OE2-SG 2.86Å
82D88.3Confident90.7Very high66 Ų6643.9 Ų43.935%0.35324%0.241SC..Hα-helixtrans-60.1-42.6177.9-70.4-26.7000112.3Q40 S78 G79 G84Q40-D82 PolarHBondContact NE2-OD2 3.42Å; S78-D82 PolarHBondContact O-N 3.44Å; G79-D82 PolarHBondContact O-N 3.03Å; D82-G84 VanDerWaalsContact C-N 3.26Å; D82-G84 PolarHBondContact O-N 3.1Å
83V88.3Confident90.6Very high17 Ų1742.2 Ų42.210%0.10323%0.23CC..Hα-helixtrans-70.3-23.5174.6169.10000112.1G79 E81 L85 Y123 I124 H127G79-V83 WeakPolarHBondContact O-CB 3.42Å; G79-V83 VanDerWaalsContact O-CG2 3.25Å; G79-V83 WeakPolarHBondContact O-CG2 3.37Å; G79-V83 PolarHBondContact O-N 3.46Å; E81-V83 VanDerWaalsContact C-N 3.34Å; E81-V83 PolarHBondContact O-N 3.43Å; V83-L85 HydrophobicContact CG1-CD2 3.83Å; V83-L85 HydrophobicContact CG1-CG 4.14Å; V83-Y123 HydrophobicContact CG1-CD1 4.13Å; V83-Y123 HydrophobicContact CG1-CE1 3.55Å; V83-I124 HydrophobicContact CG2-CG1 4.34Å; V83-H127 HydrophobicContact CG2-CB 4.09Å; V83-H127 VanDerWaalsContact CG2-CD2 3.44Å; V83-H127 WeakPolarHBondContact CG2-CD2 3.23Å
84G89.2Confident90.7Very high25 Ų2540.2 Ų40.226%0.25822%0.222SC..THydrogen-bonded Turntrans70.849.6-177.900000113.1A80 E81 D82A80-G84 PolarHBondContact O-N 2.84Å; A80-G84 VanDerWaalsContact O-N 3.14Å; E81-G84 WeakPolarHBondContact O-CA 3.39Å; E81-G84 PolarHBondContact O-N 3.37Å; D82-G84 VanDerWaalsContact C-N 3.26Å; D82-G84 PolarHBondContact O-N 3.1Å
85L90.4Very high90.7Very high17 Ų1735.5 Ų35.59%0.08920%0.198CC..  trans-64.4144.1175.3-67-175.4000111.4A80 V83 G96 F97 L116 E120 I124A80-L85 HydrophobicContact CB-CD1 3.85Å; A80-L85 HydrophobicContact CB-CG 4.38Å; A80-L85 PolarHBondContact O-N 3.11Å; V83-L85 HydrophobicContact CG1-CD2 3.83Å; V83-L85 HydrophobicContact CG1-CG 4.14Å; L85-G96 CarbonylContact O-C 3.59Å; L85-G96 WeakPolarHBondContact O-CA 3.49Å; L85-F97 WeakPolarHBondContact O-CB 3.23Å; L85-F97 PolarHBondContact O-N 2.83Å; L85-L116 HydrophobicContact CD1-CD2 4.13Å; L85-E120 HydrophobicContact CD1-CB 4.31Å; L85-E120 HydrophobicContact CD1-CG 4.3Å; L85-I124 HydrophobicContact CD1-CD1 4.23Å
86F91.5Very high90.7Very high43 Ų4335.6 Ų35.619%0.18921%0.206CC..EExtended strand (participates in β ladder)trans-108.1132174-85.7-109.4000109.9R95 G270 S273 L626F86-R95 VanDerWaalsContact CA-O 3.32Å; F86-R95 WeakPolarHBondContact CA-O 3.27Å; F86-R95 VanDerWaalsContact CD1-C 3.41Å; F86-G270 VanDerWaalsContact CB-O 3.28Å; F86-G270 WeakPolarHBondContact CB-O 3.09Å; F86-S273 VanDerWaalsContact CE1-CB 3.45Å; F86-L626 HydrophobicContact CE1-CD2 4.3Å
87K91.8Very high90.6Very high30 Ų3035.4 Ų35.413%0.1321%0.205CC..EExtended strand (participates in β ladder)trans-134.8160.8-177.5-65.9-76.1-168.4166.40110.3Y89 R95 F105 F115 E120K87-Y89 PolarHBondContact O-N 2.96Å; K87-R95 PolarHBondContact N-O 3Å; K87-R95 PolarHBondContact O-N 3.31Å; K87-F105 HydrophobicContact CB-CD1 3.55Å; K87-F105 HydrophobicContact CB-CE1 3.73Å; K87-F105 HydrophobicContact CB-CG 4.48Å; K87-F115 HydrophobicContact CB-CE2 4.45Å; K87-F115 HydrophobicContact CB-CZ 4.08Å; K87-F115 HydrophobicContact CD-CE2 4.5Å; K87-F115 HydrophobicContact CD-CZ 4.24Å; K87-F115 HydrophobicContact CG-CE1 4.41Å; K87-F115 HydrophobicContact CG-CE2 4.33Å; K87-F115 HydrophobicContact CG-CZ 3.73Å; K87-F115 PolarHBondContact NZ-O 2.79Å; K87-E120 VanDerWaalsContact CE-OE1 3.25Å; K87-E120 WeakPolarHBondContact CE-OE1 3.42Å; K87-E120 IonicContact NZ-OE1 2.63Å; K87-E120 PolarHBondContact NZ-OE1 2.98Å; K87-E120 IonicContact NZ-OE2 3.66Å; K87-E120 PolarHBondContact NZ-OE2 3.18Å
88E91.5Very high90.5Very high55 Ų5536.8 Ų36.826%0.25721%0.214SC..EExtended strand (participates in β ladder)trans-74.6122.9178.8-161.5-171.1164.500110.2M94 K106E88-M94 HydrophobicContact CB-SD 3.91Å; E88-M94 HydrophobicContact CG-SD 4.3Å; E88-K106 HydrophobicContact CG-CD 4.31Å; E88-K106 PolarHBondContact O-N 3.34Å; E88-K106 IonicContact OE1-NZ 3.06Å; E88-K106 PolarHBondContact OE1-NZ 3.44Å; E88-K106 WeakPolarHBondContact OE2-CD 3.5Å; E88-K106 IonicContact OE2-NZ 2.8Å; E88-K106 PolarHBondContact OE2-NZ 3.13Å
89Y91.4Very high90.4Very high33 Ų3337.1 Ų37.113%0.12922%0.216CC..BIsolated β-bridgetrans-74.3162169.5-111.3-124.8000111K87 D91 G92 S93 R95 N101 N104 F105K87-Y89 PolarHBondContact O-N 2.96Å; Y89-D91 WeakPolarHBondContact CB-OD1 3.31Å; Y89-D91 PolarHBondContact O-N 3.44Å; Y89-G92 PolarHBondContact O-N 3.23Å; Y89-S93 WeakPolarHBondContact CB-O 3.36Å; Y89-S93 PolarHBondContact N-O 3.15Å; Y89-R95 HydrophobicContact CD2-CB 3.67Å; Y89-R95 HydrophobicContact CD2-CG 3.81Å; Y89-R95 HydrophobicContact CE2-CB 3.75Å; Y89-R95 HydrophobicContact CE2-CG 4.11Å; Y89-R95 HydrophobicContact CG-CB 4.46Å; Y89-R95 HydrophobicContact CG-CG 4.1Å; Y89-N101 VanDerWaalsContact OH-CB 3.31Å; Y89-N101 WeakPolarHBondContact OH-CB 3.29Å; Y89-N101 PolarHBondContact OH-ND2 3.45Å; Y89-N104 HydrophobicContact CD1-CB 4.04Å; Y89-N104 HydrophobicContact CE1-CB 3.47Å; Y89-N104 VanDerWaalsContact CE1-CB 3.47Å; Y89-N104 HydrophobicContact CE2-CB 4.33Å; Y89-F105 AromaticContact CD2-CD1 3.59Å; Y89-F105 HydrophobicContact CD2-CD1 3.59Å; Y89-F105 AromaticContact CD2-CE1 3.37Å; Y89-F105 HydrophobicContact CD2-CE1 3.37Å; Y89-F105 HydrophobicContact CD2-CE2 4.39Å; Y89-F105 HydrophobicContact CD2-CG 4.2Å; Y89-F105 AromaticContact CD2-CZ 3.8Å; Y89-F105 HydrophobicContact CD2-CZ 3.8Å; Y89-F105 AromaticContact CE2-CD1 3.99Å; Y89-F105 HydrophobicContact CE2-CD1 3.99Å; Y89-F105 HydrophobicContact CE2-CD2 4.25Å; Y89-F105 AromaticContact CE2-CE1 3.49Å; Y89-F105 HydrophobicContact CE2-CE1 3.49Å; Y89-F105 VanDerWaalsContact CE2-CE1 3.49Å; Y89-F105 AromaticContact CE2-CE2 3.79Å; Y89-F105 HydrophobicContact CE2-CE2 3.79Å; Y89-F105 HydrophobicContact CE2-CG 4.35Å; Y89-F105 AromaticContact CE2-CZ 3.37Å; Y89-F105 HydrophobicContact CE2-CZ 3.37Å
90S89.9Confident90.3Very high87 Ų8743.2 Ų43.261%0.60825%0.253SS*.THydrogen-bonded Turntrans-60.4-16.8176.3-57.60000114.6N104S90-N104 PolarHBondContact N-O 3.31Å; S90-N104 PolarHBondContact OG-O 3.25Å; S90-N104 VanDerWaalsContact OG-O 3.08Å
91D88.3Confident90.1Very high98 Ų9844.4 Ų44.452%0.52426%0.26SS..THydrogen-bonded Turntrans-880.4174.169-2.1000113.7Y89 S93 R95Y89-D91 WeakPolarHBondContact CB-OD1 3.31Å; Y89-D91 PolarHBondContact O-N 3.44Å; D91-S93 VanDerWaalsContact C-N 3.32Å; D91-S93 VanDerWaalsContact CG-OG 3.24Å; D91-S93 WeakPolarHBondContact OD1-CB 3.29Å; D91-S93 PolarHBondContact OD1-N 3.34Å; D91-S93 PolarHBondContact OD1-OG 2.93Å; D91-S93 PolarHBondContact OD2-OG 3.38Å; D91-R95 IonicContact OD2-NH2 2.77Å; D91-R95 PolarHBondContact OD2-NH2 2.73Å
92G86.6Confident89.9Confident26 Ų2644.3 Ų44.327%0.26826%0.258SS..SBendtrans797.7-176.500000114.9Y89Y89-G92 PolarHBondContact O-N 3.23Å
93S89.3Confident90Very high25 Ų2547.1 Ų47.118%0.17527%0.269CS..  trans-84.4148.8172.570.10000111.5Y89 D91 R95Y89-S93 WeakPolarHBondContact CB-O 3.36Å; Y89-S93 PolarHBondContact N-O 3.15Å; D91-S93 VanDerWaalsContact C-N 3.32Å; D91-S93 VanDerWaalsContact CG-OG 3.24Å; D91-S93 WeakPolarHBondContact OD1-CB 3.29Å; D91-S93 PolarHBondContact OD1-N 3.34Å; D91-S93 PolarHBondContact OD1-OG 2.93Å; D91-S93 PolarHBondContact OD2-OG 3.38Å; S93-R95 PolarHBondContact OG-NE 3.35Å
94M91.3Very high90.1Very high12 Ų1250.3 Ų50.36%0.05929%0.285CS..EExtended strand (participates in β ladder)trans-91.5120173.8-67.2-59.3-73.100109.3E88 Y267E88-M94 HydrophobicContact CB-SD 3.91Å; E88-M94 HydrophobicContact CG-SD 4.3Å; M94-Y267 HydrophobicContact CB-CE2 4.32Å; M94-Y267 HydrophobicContact CG-CD1 4.46Å; M94-Y267 HydrophobicContact CG-CE1 3.82Å; M94-Y267 HydrophobicContact CG-CE2 4.21Å
95R91.3Very high90.2Very high61 Ų6149.2 Ų49.223%0.2327%0.273CS..EExtended strand (participates in β ladder)trans-131.1154-178.9-57-167.3-171.1-122.5-2.2111.5F86 K87 Y89 D91 S93 E629F86-R95 VanDerWaalsContact CA-O 3.32Å; F86-R95 WeakPolarHBondContact CA-O 3.27Å; F86-R95 VanDerWaalsContact CD1-C 3.41Å; K87-R95 PolarHBondContact N-O 3Å; K87-R95 PolarHBondContact O-N 3.31Å; Y89-R95 HydrophobicContact CD2-CB 3.67Å; Y89-R95 HydrophobicContact CD2-CG 3.81Å; Y89-R95 HydrophobicContact CE2-CB 3.75Å; Y89-R95 HydrophobicContact CE2-CG 4.11Å; Y89-R95 HydrophobicContact CG-CB 4.46Å; Y89-R95 HydrophobicContact CG-CG 4.1Å; D91-R95 IonicContact OD2-NH2 2.77Å; D91-R95 PolarHBondContact OD2-NH2 2.73Å; S93-R95 PolarHBondContact OG-NE 3.35Å; R95-E629 IonicContact CZ-OE2 2.82Å; R95-E629 IonicContact NH1-OE2 3.53Å; R95-E629 PolarHBondContact NH1-OE2 3.41Å; R95-E629 IonicContact NH2-OE1 3.89Å; R95-E629 IonicContact NH2-OE2 3.77Å; R95-E629 PolarHBondContact NH2-OE2 3.48Å
96G90.6Very high90.1Very high26 Ų2653.3 Ų53.327%0.26829%0.29SS..EExtended strand (participates in β ladder)trans-64.7134.2172.700000110.9L85L85-G96 CarbonylContact O-C 3.59Å; L85-G96 WeakPolarHBondContact O-CA 3.49Å
97F91.8Very high89.8Confident5 Ų556.1 Ų56.12%0.02231%0.307CS..  trans-71.2132.4177.2-178.3-97.1000111L77 A80 E81 L85 K102 F105 F115L77-F97 HydrophobicContact CB-CE1 4.18Å; L77-F97 HydrophobicContact CB-CZ 4.24Å; L77-F97 HydrophobicContact CD2-CE1 4.29Å; L77-F97 HydrophobicContact CD2-CZ 3.79Å; L77-F97 HydrophobicContact CG-CZ 4.49Å; L77-F97 WeakPolarHBondContact O-CE1 3.34Å; A80-F97 HydrophobicContact CB-CD1 3.82Å; A80-F97 HydrophobicContact CB-CE1 4.13Å; E81-F97 HydrophobicContact CB-CD1 4.32Å; L85-F97 WeakPolarHBondContact O-CB 3.23Å; L85-F97 PolarHBondContact O-N 2.83Å; F97-K102 HydrophobicContact CE2-CB 4.05Å; F97-K102 HydrophobicContact CZ-CB 4.19Å; F97-F105 HydrophobicContact CB-CZ 4.21Å; F97-F105 AromaticContact CD2-CD2 3.89Å; F97-F105 HydrophobicContact CD2-CD2 3.89Å; F97-F105 AromaticContact CD2-CE2 3.52Å; F97-F105 HydrophobicContact CD2-CE2 3.52Å; F97-F105 AromaticContact CD2-CZ 3.95Å; F97-F105 HydrophobicContact CD2-CZ 3.95Å; F97-F105 HydrophobicContact CE2-CD2 4.17Å; F97-F105 HydrophobicContact CE2-CE2 4.09Å; F97-F105 HydrophobicContact CG-CE2 4.41Å; F97-F115 AromaticContact CD2-CE1 3.56Å; F97-F115 HydrophobicContact CD2-CE1 3.56Å; F97-F115 AromaticContact CD2-CZ 3.69Å; F97-F115 HydrophobicContact CD2-CZ 3.69Å; F97-F115 HydrophobicContact CE2-CD1 4.36Å; F97-F115 AromaticContact CE2-CE1 3.41Å; F97-F115 HydrophobicContact CE2-CE1 3.41Å; F97-F115 VanDerWaalsContact CE2-CE1 3.41Å; F97-F115 AromaticContact CE2-CZ 3.81Å; F97-F115 HydrophobicContact CE2-CZ 3.81Å; F97-F115 HydrophobicContact CG-CE1 4.41Å; F97-F115 HydrophobicContact CZ-CE1 4.17Å
98T91.5Very high89.6Confident36 Ų3655.5 Ų55.522%0.22131%0.305CS..  trans-135.6150.8166.670.70000109.3E81 T100 N101 K102E81-T98 HydrophobicContact CG-CG2 4.44Å; E81-T98 WeakPolarHBondContact OE1-CB 3.41Å; T98-T100 PolarHBondContact O-N 2.96Å; T98-T100 VanDerWaalsContact O-N 3.16Å; T98-T100 PolarHBondContact OG1-OG1 2.95Å; T98-T100 VanDerWaalsContact OG1-OG1 3.04Å; T98-N101 WeakPolarHBondContact CA-OD1 3.22Å; T98-N101 WeakPolarHBondContact CB-OD1 3.38Å; T98-N101 PolarHBondContact N-OD1 3.02Å; T98-N101 PolarHBondContact O-N 3.48Å; T98-N101 PolarHBondContact O-OD1 3.41Å; T98-N101 PolarHBondContact OG1-N 2.82Å; T98-N101 PolarHBondContact OG1-ND2 2.77Å; T98-N101 PolarHBondContact OG1-OD1 3.08Å; T98-K102 PolarHBondContact O-N 3.48Å
99C88.9Confident89.1Confident46 Ų4660.1 Ų60.131%0.31133%0.326SS..G310 helixtrans-61.9-26.5177.9-670000112.2E81 K102E81-C99 WeakPolarHBondContact OE2-CB 3.33Å; E81-C99 PolarHBondContact OE2-N 2.88Å; E81-C99 PolarHBondContact OE2-SG 2.86Å; C99-K102 WeakPolarHBondContact O-CD 3.46Å; C99-K102 WeakPolarHBondContact O-CG 3.36Å
100T89.6Confident88.6Confident128 Ų12861.8 Ų61.879%0.78535%0.354SS*.G310 helixtrans-72.7-35.3-178.965.70000113.3T98T98-T100 PolarHBondContact O-N 2.96Å; T98-T100 VanDerWaalsContact O-N 3.16Å; T98-T100 PolarHBondContact OG1-OG1 2.95Å; T98-T100 VanDerWaalsContact OG1-OG1 3.04Å
101N88.1Confident87.6Confident26 Ų2664.2 Ų64.214%0.13936%0.36CS..G310 helixtrans-102.913.4-176.768.3-8.3000113.9Y89 T98 H103 N104 F105Y89-N101 VanDerWaalsContact OH-CB 3.31Å; Y89-N101 WeakPolarHBondContact OH-CB 3.29Å; Y89-N101 PolarHBondContact OH-ND2 3.45Å; T98-N101 WeakPolarHBondContact CA-OD1 3.22Å; T98-N101 WeakPolarHBondContact CB-OD1 3.38Å; T98-N101 PolarHBondContact N-OD1 3.02Å; T98-N101 PolarHBondContact O-N 3.48Å; T98-N101 PolarHBondContact O-OD1 3.41Å; T98-N101 PolarHBondContact OG1-N 2.82Å; T98-N101 PolarHBondContact OG1-ND2 2.77Å; T98-N101 PolarHBondContact OG1-OD1 3.08Å; N101-H103 VanDerWaalsContact C-N 3.26Å; N101-H103 PolarHBondContact O-N 3.14Å; N101-H103 VanDerWaalsContact O-N 3.1Å; N101-N104 WeakPolarHBondContact O-CB 3.35Å; N101-N104 PolarHBondContact O-N 3.11Å; N101-F105 VanDerWaalsContact OD1-CE2 3.3Å; N101-F105 WeakPolarHBondContact OD1-CE2 3.45Å
102K88.3Confident86.8Confident68 Ų6859.5 Ų59.530%0.29634%0.335SS..G310 helixtrans-50.2-38.2-174.665.8-174.6-178.6175.20114.9F97 T98 C99 N104 F105 F108F97-K102 HydrophobicContact CE2-CB 4.05Å; F97-K102 HydrophobicContact CZ-CB 4.19Å; T98-K102 PolarHBondContact O-N 3.48Å; C99-K102 WeakPolarHBondContact O-CD 3.46Å; C99-K102 WeakPolarHBondContact O-CG 3.36Å; K102-N104 PolarHBondContact O-N 3.01Å; K102-F105 WeakPolarHBondContact O-CD2 3.45Å; K102-F105 PolarHBondContact O-N 3.17Å; K102-F108 HydrophobicContact CB-CD1 4.48Å; K102-F108 HydrophobicContact CB-CD2 4.24Å; K102-F108 HydrophobicContact CB-CE1 4.28Å; K102-F108 HydrophobicContact CB-CE2 4.02Å; K102-F108 HydrophobicContact CB-CG 4.49Å; K102-F108 HydrophobicContact CB-CZ 4.05Å; K102-F108 HydrophobicContact CD-CE1 4.14Å; K102-F108 HydrophobicContact CD-CE2 4.35Å; K102-F108 HydrophobicContact CD-CZ 3.73Å; K102-F108 HydrophobicContact CG-CE1 4Å; K102-F108 HydrophobicContact CG-CE2 4.45Å; K102-F108 HydrophobicContact CG-CZ 3.98Å; K102-F108 WeakPolarHBondContact O-CB 3.43Å; K102-F108 WeakPolarHBondContact O-CD1 3.48Å; K102-F108 WeakPolarHBondContact O-CG 3.29Å
103H89.7Confident86Confident126 Ų12664.7 Ų64.758%0.58336%0.356SS*.G310 helixtrans-73.4-10.1-178.6-59.5-65.1000114.6N101 F108N101-H103 VanDerWaalsContact C-N 3.26Å; N101-H103 PolarHBondContact O-N 3.14Å; N101-H103 VanDerWaalsContact O-N 3.1Å; H103-F108 AromaticContact CE1-CE1 3.82Å; H103-F108 AromaticContact ND1-CD1 3.84Å; H103-F108 AromaticContact ND1-CE1 3.65Å
104N90.4Very high85.4Confident83 Ų8366.7 Ų66.744%0.44438%0.38SS..G310 helixtrans-90.6-4.2179.4-60.8-30.2000112.9Y89 S90 N101 K102Y89-N104 HydrophobicContact CD1-CB 4.04Å; Y89-N104 HydrophobicContact CE1-CB 3.47Å; Y89-N104 VanDerWaalsContact CE1-CB 3.47Å; Y89-N104 HydrophobicContact CE2-CB 4.33Å; S90-N104 PolarHBondContact N-O 3.31Å; S90-N104 PolarHBondContact OG-O 3.25Å; S90-N104 VanDerWaalsContact OG-O 3.08Å; N101-N104 WeakPolarHBondContact O-CB 3.35Å; N101-N104 PolarHBondContact O-N 3.11Å; K102-N104 PolarHBondContact O-N 3.01Å
105F91.9Very high85.3Confident3 Ų366.5 Ų66.51%0.01338%0.379CS..BIsolated β-bridgetrans-85.4140176-67.7-83.8000111K87 Y89 F97 N101 K102 D107 F108 F115K87-F105 HydrophobicContact CB-CD1 3.55Å; K87-F105 HydrophobicContact CB-CE1 3.73Å; K87-F105 HydrophobicContact CB-CG 4.48Å; Y89-F105 AromaticContact CD2-CD1 3.59Å; Y89-F105 HydrophobicContact CD2-CD1 3.59Å; Y89-F105 AromaticContact CD2-CE1 3.37Å; Y89-F105 HydrophobicContact CD2-CE1 3.37Å; Y89-F105 HydrophobicContact CD2-CE2 4.39Å; Y89-F105 HydrophobicContact CD2-CG 4.2Å; Y89-F105 AromaticContact CD2-CZ 3.8Å; Y89-F105 HydrophobicContact CD2-CZ 3.8Å; Y89-F105 AromaticContact CE2-CD1 3.99Å; Y89-F105 HydrophobicContact CE2-CD1 3.99Å; Y89-F105 HydrophobicContact CE2-CD2 4.25Å; Y89-F105 AromaticContact CE2-CE1 3.49Å; Y89-F105 HydrophobicContact CE2-CE1 3.49Å; Y89-F105 VanDerWaalsContact CE2-CE1 3.49Å; Y89-F105 AromaticContact CE2-CE2 3.79Å; Y89-F105 HydrophobicContact CE2-CE2 3.79Å; Y89-F105 HydrophobicContact CE2-CG 4.35Å; Y89-F105 AromaticContact CE2-CZ 3.37Å; Y89-F105 HydrophobicContact CE2-CZ 3.37Å; F97-F105 HydrophobicContact CB-CZ 4.21Å; F97-F105 AromaticContact CD2-CD2 3.89Å; F97-F105 HydrophobicContact CD2-CD2 3.89Å; F97-F105 AromaticContact CD2-CE2 3.52Å; F97-F105 HydrophobicContact CD2-CE2 3.52Å; F97-F105 AromaticContact CD2-CZ 3.95Å; F97-F105 HydrophobicContact CD2-CZ 3.95Å; F97-F105 HydrophobicContact CE2-CD2 4.17Å; F97-F105 HydrophobicContact CE2-CE2 4.09Å; F97-F105 HydrophobicContact CG-CE2 4.41Å; N101-F105 VanDerWaalsContact OD1-CE2 3.3Å; N101-F105 WeakPolarHBondContact OD1-CE2 3.45Å; K102-F105 WeakPolarHBondContact O-CD2 3.45Å; K102-F105 PolarHBondContact O-N 3.17Å; F105-D107 VanDerWaalsContact C-N 3.34Å; F105-D107 PolarHBondContact O-N 3.35Å; F105-F108 HydrophobicContact CB-CB 4.16Å; F105-F108 PolarHBondContact O-N 2.99Å; F105-F115 HydrophobicContact CB-CE2 3.76Å; F105-F115 HydrophobicContact CB-CZ 4.07Å; F105-F115 HydrophobicContact CD2-CZ 4.45Å; F105-F115 HydrophobicContact CG-CE2 4.28Å; F105-F115 HydrophobicContact CG-CZ 4.11Å
106K87.8Confident85.4Confident103 Ų10364 Ų6445%0.44837%0.371SS..THydrogen-bonded Turntrans-58.7-42-170.8179.9179.9173.3-174.40113.7E88E88-K106 HydrophobicContact CG-CD 4.31Å; E88-K106 PolarHBondContact O-N 3.34Å; E88-K106 IonicContact OE1-NZ 3.06Å; E88-K106 PolarHBondContact OE1-NZ 3.44Å; E88-K106 WeakPolarHBondContact OE2-CD 3.5Å; E88-K106 IonicContact OE2-NZ 2.8Å; E88-K106 PolarHBondContact OE2-NZ 3.13Å
107D85.5Confident85.4Confident102 Ų10263.2 Ų63.255%0.54536%0.361SS..THydrogen-bonded Turntrans-945.3-175-56-40.2000112.9F105 Q109 F115F105-D107 VanDerWaalsContact C-N 3.34Å; F105-D107 PolarHBondContact O-N 3.35Å; D107-Q109 PolarHBondContact O-N 2.92Å; D107-F115 HydrophobicContact CB-CD2 4.22Å
108F87.8Confident85.4Confident16 Ų1664.1 Ų64.17%0.0737%0.365CS..  trans-87.1107.1-179.7-166-85.4000110.5L77 K102 H103 F105 F115L77-F108 HydrophobicContact CD1-CE2 4.2Å; L77-F108 HydrophobicContact CD2-CE2 4.36Å; K102-F108 HydrophobicContact CB-CD1 4.48Å; K102-F108 HydrophobicContact CB-CD2 4.24Å; K102-F108 HydrophobicContact CB-CE1 4.28Å; K102-F108 HydrophobicContact CB-CE2 4.02Å; K102-F108 HydrophobicContact CB-CG 4.49Å; K102-F108 HydrophobicContact CB-CZ 4.05Å; K102-F108 HydrophobicContact CD-CE1 4.14Å; K102-F108 HydrophobicContact CD-CE2 4.35Å; K102-F108 HydrophobicContact CD-CZ 3.73Å; K102-F108 HydrophobicContact CG-CE1 4Å; K102-F108 HydrophobicContact CG-CE2 4.45Å; K102-F108 HydrophobicContact CG-CZ 3.98Å; K102-F108 WeakPolarHBondContact O-CB 3.43Å; K102-F108 WeakPolarHBondContact O-CD1 3.48Å; K102-F108 WeakPolarHBondContact O-CG 3.29Å; H103-F108 AromaticContact CE1-CE1 3.82Å; H103-F108 AromaticContact ND1-CD1 3.84Å; H103-F108 AromaticContact ND1-CE1 3.65Å; F105-F108 HydrophobicContact CB-CB 4.16Å; F105-F108 PolarHBondContact O-N 2.99Å; F108-F115 HydrophobicContact CB-CD2 4.04Å; F108-F115 HydrophobicContact CB-CE2 4.26Å; F108-F115 HydrophobicContact CD2-CB 4.17Å; F108-F115 HydrophobicContact CD2-CD1 4Å; F108-F115 HydrophobicContact CD2-CD2 4.09Å; F108-F115 HydrophobicContact CD2-CE1 4.43Å; F108-F115 HydrophobicContact CD2-CE2 4.5Å; F108-F115 AromaticContact CD2-CG 3.82Å; F108-F115 HydrophobicContact CD2-CG 3.82Å
109Q81.6Confident85.5Confident153 Ų15362.5 Ų62.572%0.71536%0.356SS*.  trans-126.7143.9178.2-61.6-174.77.600111.6D107 D111 G112D107-Q109 PolarHBondContact O-N 2.92Å; Q109-D111 PolarHBondContact O-N 2.99Å; Q109-G112 WeakPolarHBondContact O-CA 3.31Å; Q109-G112 PolarHBondContact O-N 3.46Å
110G80.2Confident85.7Confident68 Ų6861.1 Ų61.170%0.70135%0.345SS*.THydrogen-bonded Turntrans57.1-125.8178.600000112.5G112G110-G112 PolarHBondContact O-N 3.04Å
111D69.6Low86Confident137 Ų13755.3 Ų55.373%0.73331%0.309SS*.THydrogen-bonded Turntrans-78.4-7.1177.5-62.5-27.4000112.8W73 Q109W73-D111 PolarHBondContact NE1-O 2.57Å; Q109-D111 PolarHBondContact O-N 2.99Å
112G70.4Confident86.3Confident0 Ų054.1 Ų54.10%030%0.303CS..  trans98.35-179.100000114W73 Q109 G110 G114 F115W73-G112 WeakPolarHBondContact CZ2-O 3.36Å; Q109-G112 WeakPolarHBondContact O-CA 3.31Å; Q109-G112 PolarHBondContact O-N 3.46Å; G110-G112 PolarHBondContact O-N 3.04Å; G112-G114 PolarHBondContact O-N 3.36Å; G112-F115 WeakPolarHBondContact O-CB 3.49Å; G112-F115 PolarHBondContact O-N 3.37Å
113D70Confident86.6Confident135 Ų13552.4 Ų52.472%0.72230%0.295SS*.THydrogen-bonded Turntrans-51.4122.5177.5-86.4-14.6000111.5
114G77.1Confident86.9Confident66 Ų6646.5 Ų46.568%0.6827%0.267SS*.THydrogen-bonded Turntrans85.8-0.5-178.100000115.9G112G112-G114 PolarHBondContact O-N 3.36Å
115F90Very high87.1Confident9 Ų942.5 Ų42.54%0.03925%0.246CC..SBendtrans-68.1-39.4175.6173.6-108.8000113.1W73 L77 K87 F97 F105 D107 F108 G112W73-F115 HydrophobicContact CZ2-CB 4.18Å; L77-F115 HydrophobicContact CD2-CD1 4.14Å; K87-F115 HydrophobicContact CB-CE2 4.45Å; K87-F115 HydrophobicContact CB-CZ 4.08Å; K87-F115 HydrophobicContact CD-CE2 4.5Å; K87-F115 HydrophobicContact CD-CZ 4.24Å; K87-F115 HydrophobicContact CG-CE1 4.41Å; K87-F115 HydrophobicContact CG-CE2 4.33Å; K87-F115 HydrophobicContact CG-CZ 3.73Å; K87-F115 PolarHBondContact NZ-O 2.79Å; F97-F115 AromaticContact CD2-CE1 3.56Å; F97-F115 HydrophobicContact CD2-CE1 3.56Å; F97-F115 AromaticContact CD2-CZ 3.69Å; F97-F115 HydrophobicContact CD2-CZ 3.69Å; F97-F115 HydrophobicContact CE2-CD1 4.36Å; F97-F115 AromaticContact CE2-CE1 3.41Å; F97-F115 HydrophobicContact CE2-CE1 3.41Å; F97-F115 VanDerWaalsContact CE2-CE1 3.41Å; F97-F115 AromaticContact CE2-CZ 3.81Å; F97-F115 HydrophobicContact CE2-CZ 3.81Å; F97-F115 HydrophobicContact CG-CE1 4.41Å; F97-F115 HydrophobicContact CZ-CE1 4.17Å; F105-F115 HydrophobicContact CB-CE2 3.76Å; F105-F115 HydrophobicContact CB-CZ 4.07Å; F105-F115 HydrophobicContact CD2-CZ 4.45Å; F105-F115 HydrophobicContact CG-CE2 4.28Å; F105-F115 HydrophobicContact CG-CZ 4.11Å; D107-F115 HydrophobicContact CB-CD2 4.22Å; F108-F115 HydrophobicContact CB-CD2 4.04Å; F108-F115 HydrophobicContact CB-CE2 4.26Å; F108-F115 HydrophobicContact CD2-CB 4.17Å; F108-F115 HydrophobicContact CD2-CD1 4Å; F108-F115 HydrophobicContact CD2-CD2 4.09Å; F108-F115 HydrophobicContact CD2-CE1 4.43Å; F108-F115 HydrophobicContact CD2-CE2 4.5Å; F108-F115 AromaticContact CD2-CG 3.82Å; F108-F115 HydrophobicContact CD2-CG 3.82Å; G112-F115 WeakPolarHBondContact O-CB 3.49Å; G112-F115 PolarHBondContact O-N 3.37Å
116L92.1Very high87.2Confident9 Ų943.8 Ų43.85%0.04725%0.252CS..SBendtrans-94.4133172.8-57.5175.6000109.2W73 L76 L77 A80 L85 E120 C121 I124W73-L116 HydrophobicContact CH2-CB 3.67Å; W73-L116 HydrophobicContact CH2-CD1 3.99Å; W73-L116 HydrophobicContact CH2-CG 3.8Å; W73-L116 HydrophobicContact CZ2-CD1 4.4Å; W73-L116 HydrophobicContact CZ2-CG 4.21Å; W73-L116 HydrophobicContact CZ3-CB 4.31Å; W73-L116 HydrophobicContact CZ3-CD1 4.4Å; L76-L116 HydrophobicContact CB-CD1 3.98Å; L77-L116 HydrophobicContact CD2-CD1 4.18Å; L77-L116 HydrophobicContact CD2-CG 4.44Å; A80-L116 HydrophobicContact CB-CD1 4.28Å; A80-L116 HydrophobicContact CB-CD2 4.14Å; L85-L116 HydrophobicContact CD1-CD2 4.13Å; L116-E120 WeakPolarHBondContact CA-OE2 3.46Å; L116-E120 HydrophobicContact CB-CB 4.49Å; L116-C121 VanDerWaalsContact CB-SG 3.58Å; L116-I124 HydrophobicContact CD1-CD1 4.01Å
117S91.9Very high87.4Confident8 Ų840.2 Ų40.26%0.05624%0.236CC..  trans-68.3157.6171.677.50000110.3A119 E120 C121 H199S117-A119 PolarHBondContact O-N 3.48Å; S117-A119 PolarHBondContact OG-N 2.77Å; S117-E120 PolarHBondContact N-OE2 3.24Å; S117-E120 WeakPolarHBondContact O-CB 3.48Å; S117-E120 PolarHBondContact O-N 2.98Å; S117-E120 VanDerWaalsContact O-N 3.11Å; S117-E120 VanDerWaalsContact OG-CG 3.29Å; S117-E120 WeakPolarHBondContact OG-CG 3.42Å; S117-E120 PolarHBondContact OG-N 3.45Å; S117-E120 VanDerWaalsContact OG-N 3.07Å; S117-C121 PolarHBondContact O-N 3Å; S117-C121 PolarHBondContact O-SG 2.93Å; S117-H199 WeakPolarHBondContact CB-CE1 3.28Å; S117-H199 WeakPolarHBondContact CB-ND1 3.07Å
118M90.4Very high87.7Confident24 Ų2435.7 Ų35.712%0.11821%0.212CC..Hα-helixtrans-60.4-34.2175.4-168.3-178.2-168.900111.9L15 C121 Q122 H172 R542L15-M118 HydrophobicContact CD2-CE 3.82Å; L15-M118 HydrophobicContact CD2-CG 3.99Å; M118-C121 PolarHBondContact O-N 3.03Å; M118-Q122 WeakPolarHBondContact O-CB 3.38Å; M118-Q122 VanDerWaalsContact O-CG 3.24Å; M118-Q122 WeakPolarHBondContact O-CG 3.45Å; M118-Q122 PolarHBondContact O-N 2.77Å; M118-H172 HydrophobicContact CE-CB 4.32Å; M118-H172 HydrophobicContact SD-CB 3.66Å; M118-R542 PolarHBondContact SD-NH1 2.87Å
119A93.6Very high88Confident3 Ų335 Ų353%0.02521%0.209CC..Hα-helixtrans-63.1-42.6175.900000111.6S117 Q122 Y123 H199 A545S117-A119 PolarHBondContact O-N 3.48Å; S117-A119 PolarHBondContact OG-N 2.77Å; A119-Q122 PolarHBondContact O-N 3.38Å; A119-Y123 WeakPolarHBondContact O-CB 3.27Å; A119-Y123 PolarHBondContact O-N 3.09Å; A119-H199 WeakPolarHBondContact CB-O 3.36Å; A119-A545 HydrophobicContact CB-CB 4.07Å
120E94.2Very high88.3Confident16 Ų1630.1 Ų30.18%0.07519%0.186CC..Hα-helixtrans-65.6-45.1175-71.2166.815900111.4L85 K87 L116 S117 Q122 Y123 I124L85-E120 HydrophobicContact CD1-CB 4.31Å; L85-E120 HydrophobicContact CD1-CG 4.3Å; K87-E120 VanDerWaalsContact CE-OE1 3.25Å; K87-E120 WeakPolarHBondContact CE-OE1 3.42Å; K87-E120 IonicContact NZ-OE1 2.63Å; K87-E120 PolarHBondContact NZ-OE1 2.98Å; K87-E120 IonicContact NZ-OE2 3.66Å; K87-E120 PolarHBondContact NZ-OE2 3.18Å; L116-E120 WeakPolarHBondContact CA-OE2 3.46Å; L116-E120 HydrophobicContact CB-CB 4.49Å; S117-E120 PolarHBondContact N-OE2 3.24Å; S117-E120 WeakPolarHBondContact O-CB 3.48Å; S117-E120 PolarHBondContact O-N 2.98Å; S117-E120 VanDerWaalsContact O-N 3.11Å; S117-E120 VanDerWaalsContact OG-CG 3.29Å; S117-E120 WeakPolarHBondContact OG-CG 3.42Å; S117-E120 PolarHBondContact OG-N 3.45Å; S117-E120 VanDerWaalsContact OG-N 3.07Å; E120-Q122 VanDerWaalsContact C-N 3.33Å; E120-Q122 PolarHBondContact O-N 3.15Å; E120-Y123 PolarHBondContact O-N 2.93Å; E120-I124 WeakPolarHBondContact O-CD1 3.37Å; E120-I124 VanDerWaalsContact O-CG1 3.24Å; E120-I124 WeakPolarHBondContact O-CG1 3.46Å; E120-I124 PolarHBondContact O-N 3.46Å
121C94.8Very high88.6Confident7 Ų728 Ų285%0.04716%0.16CC..Hα-helixtrans-59.2-43.6177-65.50000112.1L15 L76 L116 S117 M118 I124 I125L15-C121 HydrophobicContact CD1-CB 3.81Å; L76-C121 HydrophobicContact CD1-CB 4.33Å; L76-C121 HydrophobicContact CD2-CB 4.17Å; L116-C121 VanDerWaalsContact CB-SG 3.58Å; S117-C121 PolarHBondContact O-N 3Å; S117-C121 PolarHBondContact O-SG 2.93Å; M118-C121 PolarHBondContact O-N 3.03Å; C121-I124 PolarHBondContact O-N 2.97Å; C121-I125 WeakPolarHBondContact O-CG1 3.47Å; C121-I125 PolarHBondContact O-N 3.47Å
122Q95.8Very high89.6Confident1 Ų121.8 Ų21.81%0.00513%0.127CC..Hα-helixtrans-67.8-37.6176.8-73.5171-20.400112.3L15 V16 M118 A119 E120 I125 K126 P169 L170 R542L15-Q122 HydrophobicContact CB-CG 4.03Å; L15-Q122 HydrophobicContact CD2-CG 4.42Å; L15-Q122 PolarHBondContact O-NE2 2.72Å; V16-Q122 HydrophobicContact CG2-CB 4.45Å; V16-Q122 HydrophobicContact CG2-CG 4.39Å; M118-Q122 WeakPolarHBondContact O-CB 3.38Å; M118-Q122 VanDerWaalsContact O-CG 3.24Å; M118-Q122 WeakPolarHBondContact O-CG 3.45Å; M118-Q122 PolarHBondContact O-N 2.77Å; A119-Q122 PolarHBondContact O-N 3.38Å; E120-Q122 VanDerWaalsContact C-N 3.33Å; E120-Q122 PolarHBondContact O-N 3.15Å; Q122-I125 PolarHBondContact O-N 3.19Å; Q122-K126 WeakPolarHBondContact O-CB 3.43Å; Q122-K126 PolarHBondContact O-N 2.77Å; Q122-P169 HydrophobicContact CB-CB 4.07Å; Q122-P169 HydrophobicContact CG-CB 3.94Å; Q122-L170 PolarHBondContact NE2-O 2.98Å; Q122-R542 VanDerWaalsContact OE1-NE 3.1Å; Q122-R542 VanDerWaalsContact OE1-NH1 3.08Å
123Y94.6Very high90.4Very high31 Ų3124.3 Ų24.312%0.12214%0.136CC..Hα-helixtrans-64.7-42.3174.4178.3-112.9000112.1V83 A119 E120 K126 H127 R274 A545 P547V83-Y123 HydrophobicContact CG1-CD1 4.13Å; V83-Y123 HydrophobicContact CG1-CE1 3.55Å; A119-Y123 WeakPolarHBondContact O-CB 3.27Å; A119-Y123 PolarHBondContact O-N 3.09Å; E120-Y123 PolarHBondContact O-N 2.93Å; Y123-K126 WeakPolarHBondContact O-CB 3.47Å; Y123-K126 PolarHBondContact O-N 2.81Å; Y123-H127 WeakPolarHBondContact O-CB 3.43Å; Y123-H127 PolarHBondContact O-N 3.22Å; Y123-R274 PolarHBondContact OH-NH1 3Å; Y123-A545 WeakPolarHBondContact CD2-O 3.35Å; Y123-A545 WeakPolarHBondContact CE2-O 3.48Å; Y123-P547 HydrophobicContact CD1-CG 4.25Å; Y123-P547 HydrophobicContact CE1-CG 3.64Å; Y123-P547 HydrophobicContact CE2-CG 4.2Å; Y123-P547 VanDerWaalsContact CZ-CD 3.44Å
124I94.8Very high91.3Very high2 Ų217.9 Ų17.91%0.0110%0.102CC..Hα-helixtrans-60.3-48175-68.5159.3000110L76 A80 V83 L85 L116 E120 C121 K126 H127 E128L76-I124 HydrophobicContact CD2-CG2 4.33Å; A80-I124 HydrophobicContact CB-CD1 3.83Å; V83-I124 HydrophobicContact CG2-CG1 4.34Å; L85-I124 HydrophobicContact CD1-CD1 4.23Å; L116-I124 HydrophobicContact CD1-CD1 4.01Å; E120-I124 WeakPolarHBondContact O-CD1 3.37Å; E120-I124 VanDerWaalsContact O-CG1 3.24Å; E120-I124 WeakPolarHBondContact O-CG1 3.46Å; E120-I124 PolarHBondContact O-N 3.46Å; C121-I124 PolarHBondContact O-N 2.97Å; I124-K126 PolarHBondContact O-N 3.02Å; I124-H127 WeakPolarHBondContact O-CB 3.4Å; I124-H127 PolarHBondContact O-N 3.21Å; I124-H127 VanDerWaalsContact O-N 3.16Å; I124-E128 HydrophobicContact CG2-CG 4.44Å; I124-E128 VanDerWaalsContact O-CG 3.27Å; I124-E128 WeakPolarHBondContact O-CG 3.29Å; I124-E128 PolarHBondContact O-N 3Å
125I95.6Very high91.6Very high0 Ų019.5 Ų19.50%09%0.09CC..Hα-helixtrans-61.6-43.8177.5-70172.3000111.5L15 V16 L47 V69 L76 C121 Q122 H127 E128 L129L15-I125 HydrophobicContact CB-CD1 3.7Å; L15-I125 HydrophobicContact CD1-CD1 3.46Å; L15-I125 VanDerWaalsContact CD1-CD1 3.46Å; L15-I125 HydrophobicContact CG-CD1 4.18Å; V16-I125 HydrophobicContact CB-CG2 3.98Å; V16-I125 HydrophobicContact CG2-CB 4.05Å; V16-I125 HydrophobicContact CG2-CG2 3.65Å; L47-I125 HydrophobicContact CD1-CG2 4.19Å; L47-I125 HydrophobicContact CD2-CG1 4.24Å; V69-I125 HydrophobicContact CB-CG2 4.48Å; V69-I125 HydrophobicContact CG1-CG2 3.79Å; L76-I125 HydrophobicContact CD2-CD1 4.42Å; L76-I125 HydrophobicContact CD2-CG1 4.25Å; C121-I125 WeakPolarHBondContact O-CG1 3.47Å; C121-I125 PolarHBondContact O-N 3.47Å; Q122-I125 PolarHBondContact O-N 3.19Å; I125-H127 VanDerWaalsContact C-N 3.31Å; I125-H127 PolarHBondContact O-N 3.04Å; I125-E128 PolarHBondContact O-N 2.72Å; I125-L129 HydrophobicContact CG2-CD1 3.83Å; I125-L129 HydrophobicContact CG2-CG 4.34Å; I125-L129 WeakPolarHBondContact O-CB 3.25Å; I125-L129 VanDerWaalsContact O-CG 3.28Å; I125-L129 WeakPolarHBondContact O-CG 2.9Å; I125-L129 PolarHBondContact O-N 2.97Å
126K94.3Very high91.5Very high29 Ų2926.3 Ų26.313%0.12613%0.127CC..Hα-helixtrans-55.5-49173.4167.8-179.9170.3-169.10110.5Q122 Y123 I124 E128 L129 E130 M167 F544 D546Q122-K126 WeakPolarHBondContact O-CB 3.43Å; Q122-K126 PolarHBondContact O-N 2.77Å; Y123-K126 WeakPolarHBondContact O-CB 3.47Å; Y123-K126 PolarHBondContact O-N 2.81Å; I124-K126 PolarHBondContact O-N 3.02Å; K126-E128 PolarHBondContact O-N 3Å; K126-L129 PolarHBondContact O-N 2.8Å; K126-E130 WeakPolarHBondContact CE-OE1 3.34Å; K126-E130 HydrophobicContact CG-CG 4.25Å; K126-E130 VanDerWaalsContact O-CB 3.28Å; K126-E130 WeakPolarHBondContact O-CB 3.43Å; K126-E130 WeakPolarHBondContact O-CG 3.43Å; K126-E130 PolarHBondContact O-N 3.34Å; K126-M167 HydrophobicContact CB-CE 4.47Å; K126-M167 HydrophobicContact CG-CE 3.95Å; K126-F544 HydrophobicContact CB-CD1 3.8Å; K126-F544 HydrophobicContact CB-CE1 3.71Å; K126-F544 HydrophobicContact CB-CG 4.42Å; K126-F544 HydrophobicContact CB-CZ 4.23Å; K126-F544 HydrophobicContact CD-CB 3.62Å; K126-F544 HydrophobicContact CD-CD1 3.68Å; K126-F544 HydrophobicContact CD-CD2 3.77Å; K126-F544 HydrophobicContact CD-CE1 4.23Å; K126-F544 HydrophobicContact CD-CE2 4.28Å; K126-F544 HydrophobicContact CD-CG 3.42Å; K126-F544 VanDerWaalsContact CD-CG 3.42Å; K126-F544 HydrophobicContact CG-CD1 4.27Å; K126-F544 HydrophobicContact CG-CE1 4.38Å; K126-F544 HydrophobicContact CG-CG 4.4Å; K126-D546 IonicContact NZ-OD1 2.82Å; K126-D546 PolarHBondContact NZ-OD1 2.99Å; K126-D546 VanDerWaalsContact NZ-OD1 3.14Å
127H91.5Very high91.3Very high28 Ų2827.9 Ų27.913%0.1313%0.134CC..Hα-helixtrans-55.7-54.7-179.8-176.563000110.3V83 Y123 I124 I125 L129 E130 T131V83-H127 HydrophobicContact CG2-CB 4.09Å; V83-H127 VanDerWaalsContact CG2-CD2 3.44Å; V83-H127 WeakPolarHBondContact CG2-CD2 3.23Å; Y123-H127 WeakPolarHBondContact O-CB 3.43Å; Y123-H127 PolarHBondContact O-N 3.22Å; I124-H127 WeakPolarHBondContact O-CB 3.4Å; I124-H127 PolarHBondContact O-N 3.21Å; I124-H127 VanDerWaalsContact O-N 3.16Å; I125-H127 VanDerWaalsContact C-N 3.31Å; I125-H127 PolarHBondContact O-N 3.04Å; H127-L129 VanDerWaalsContact C-N 3.33Å; H127-L129 PolarHBondContact O-N 3.19Å; H127-E130 CarbonylContact O-C 3.57Å; H127-E130 WeakPolarHBondContact O-CA 2.86Å; H127-E130 PolarHBondContact O-N 3.42Å; H127-T131 VanDerWaalsContact CE1-CG2 3.5Å; H127-T131 WeakPolarHBondContact CE1-CG2 3.28Å; H127-T131 WeakPolarHBondContact O-CG2 3.48Å; H127-T131 PolarHBondContact O-N 2.94Å; H127-T131 PolarHBondContact O-OG1 3.37Å
128E92Very high91.1Very high8 Ų832 Ų324%0.03716%0.16CC..Hα-helixtrans-61.6-35.8-178.2-63.4-69.1-174.800114Q40 A45 L47 R75 I124 I125 K126 T131 L132Q40-E128 PolarHBondContact NE2-OE1 2.73Å; Q40-E128 PolarHBondContact NE2-OE2 3.42Å; A45-E128 HydrophobicContact CB-CB 4.5Å; L47-E128 HydrophobicContact CD1-CB 4.23Å; R75-E128 IonicContact CZ-OE1 3.12Å; R75-E128 IonicContact CZ-OE2 2.9Å; R75-E128 IonicContact NH1-OE1 2.75Å; R75-E128 PolarHBondContact NH1-OE1 2.98Å; R75-E128 IonicContact NH2-OE1 2.83Å; R75-E128 PolarHBondContact NH2-OE1 3.42Å; R75-E128 IonicContact NH2-OE2 3.68Å; R75-E128 PolarHBondContact NH2-OE2 3.49Å; I124-E128 HydrophobicContact CG2-CG 4.44Å; I124-E128 VanDerWaalsContact O-CG 3.27Å; I124-E128 WeakPolarHBondContact O-CG 3.29Å; I124-E128 PolarHBondContact O-N 3Å; I125-E128 PolarHBondContact O-N 2.72Å; K126-E128 PolarHBondContact O-N 3Å; E128-T131 WeakPolarHBondContact CA-OG1 3.14Å; E128-T131 PolarHBondContact O-OG1 3.26Å; E128-L132 PolarHBondContact O-N 2.97Å
129L93Very high91.2Very high0 Ų034.7 Ų34.70%017%0.172CC..Hα-helixtrans-69.4-43.3173.1-70.8172.9000111V16 L18 I36 L47 V69 I125 K126 H127 L132 I155 M167V16-L129 HydrophobicContact CG1-CD1 4.47Å; L18-L129 HydrophobicContact CD2-CD1 4.37Å; I36-L129 HydrophobicContact CD1-CD2 4.07Å; I36-L129 HydrophobicContact CG1-CD2 3.94Å; I36-L129 HydrophobicContact CG2-CD2 4.11Å; L47-L129 HydrophobicContact CD1-CD2 3.91Å; L47-L129 HydrophobicContact CD1-CG 3.96Å; V69-L129 HydrophobicContact CG1-CD1 4.45Å; I125-L129 HydrophobicContact CG2-CD1 3.83Å; I125-L129 HydrophobicContact CG2-CG 4.34Å; I125-L129 WeakPolarHBondContact O-CB 3.25Å; I125-L129 VanDerWaalsContact O-CG 3.28Å; I125-L129 WeakPolarHBondContact O-CG 2.9Å; I125-L129 PolarHBondContact O-N 2.97Å; K126-L129 PolarHBondContact O-N 2.8Å; H127-L129 VanDerWaalsContact C-N 3.33Å; H127-L129 PolarHBondContact O-N 3.19Å; L129-L132 VanDerWaalsContact O-CB 3.28Å; L129-L132 WeakPolarHBondContact O-CB 3.36Å; L129-L132 PolarHBondContact O-N 3.48Å; L129-I155 HydrophobicContact CB-CG1 4.19Å; L129-I155 WeakPolarHBondContact O-CG1 3.28Å; L129-M167 HydrophobicContact CB-SD 4.36Å; L129-M167 HydrophobicContact CD1-SD 3.86Å
130E88.9Confident91.1Very high51 Ų5134.6 Ų34.624%0.23817%0.171CC..Hα-helixtrans-67.5-34.5179.3-79.7-177.2177.800112.5K126 H127 L132 R133 S153 M167 P283K126-E130 WeakPolarHBondContact CE-OE1 3.34Å; K126-E130 HydrophobicContact CG-CG 4.25Å; K126-E130 VanDerWaalsContact O-CB 3.28Å; K126-E130 WeakPolarHBondContact O-CB 3.43Å; K126-E130 WeakPolarHBondContact O-CG 3.43Å; K126-E130 PolarHBondContact O-N 3.34Å; H127-E130 CarbonylContact O-C 3.57Å; H127-E130 WeakPolarHBondContact O-CA 2.86Å; H127-E130 PolarHBondContact O-N 3.42Å; E130-L132 VanDerWaalsContact C-N 3.31Å; E130-R133 PolarHBondContact O-NH1 3Å; E130-S153 PolarHBondContact O-OG 2.91Å; E130-M167 HydrophobicContact CG-CE 4.44Å; E130-P283 HydrophobicContact CB-CG 3.94Å; E130-P283 HydrophobicContact CG-CG 3.77Å
131T87Confident91.1Very high24 Ų2435.4 Ų35.415%0.14718%0.177CC..Hα-helixtrans-72.6-20.9177.769.20000112.4H127 E128 R133 E280H127-T131 VanDerWaalsContact CE1-CG2 3.5Å; H127-T131 WeakPolarHBondContact CE1-CG2 3.28Å; H127-T131 WeakPolarHBondContact O-CG2 3.48Å; H127-T131 PolarHBondContact O-N 2.94Å; H127-T131 PolarHBondContact O-OG1 3.37Å; E128-T131 WeakPolarHBondContact CA-OG1 3.14Å; E128-T131 PolarHBondContact O-OG1 3.26Å; T131-R133 WeakPolarHBondContact O-CD 3.3Å; T131-R133 VanDerWaalsContact O-CG 3.24Å; T131-R133 WeakPolarHBondContact O-CG 2.81Å; T131-R133 VanDerWaalsContact O-CZ 3.31Å; T131-R133 PolarHBondContact O-N 3.3Å; T131-R133 PolarHBondContact O-NE 3.2Å; T131-R133 PolarHBondContact O-NH1 2.95Å; T131-E280 WeakPolarHBondContact CB-OE2 3.47Å; T131-E280 VanDerWaalsContact CG2-CD 3.42Å; T131-E280 WeakPolarHBondContact CG2-OE2 3.37Å
132L89.8Confident90.8Very high7 Ų736.1 Ų36.14%0.03719%0.185CC..  trans-56.6112.3-178.5-163.472000112.4R35 I36 A45 E128 L129 E130 S153 I154R35-L132 HydrophobicContact CB-CD2 4.1Å; I36-L132 HydrophobicContact CG1-CD2 4.5Å; A45-L132 HydrophobicContact CB-CD1 4.34Å; E128-L132 PolarHBondContact O-N 2.97Å; L129-L132 VanDerWaalsContact O-CB 3.28Å; L129-L132 WeakPolarHBondContact O-CB 3.36Å; L129-L132 PolarHBondContact O-N 3.48Å; E130-L132 VanDerWaalsContact C-N 3.31Å; L132-S153 WeakPolarHBondContact O-CA 3.41Å; L132-I154 HydrophobicContact CD2-CB 4.4Å; L132-I154 HydrophobicContact CD2-CD1 4.05Å; L132-I154 HydrophobicContact CG-CD1 4Å; L132-I154 PolarHBondContact O-N 3.39Å
133R87.3Confident90.6Very high52 Ų5238.5 Ų38.520%0.19620%0.195CC..BIsolated β-bridgetrans-107145.7-177.4-56.4-51.1-179.5-120.7-3.1113R35 E130 T131 G151 K152 E280R35-R133 PolarHBondContact NH2-O 3.03Å; E130-R133 PolarHBondContact O-NH1 3Å; T131-R133 WeakPolarHBondContact O-CD 3.3Å; T131-R133 VanDerWaalsContact O-CG 3.24Å; T131-R133 WeakPolarHBondContact O-CG 2.81Å; T131-R133 VanDerWaalsContact O-CZ 3.31Å; T131-R133 PolarHBondContact O-N 3.3Å; T131-R133 PolarHBondContact O-NE 3.2Å; T131-R133 PolarHBondContact O-NH1 2.95Å; R133-G151 VanDerWaalsContact CD-O 3.32Å; R133-G151 WeakPolarHBondContact CD-O 3.21Å; R133-K152 WeakPolarHBondContact CA-O 3.01Å; R133-E280 IonicContact NH2-OE2 2.86Å
134A88.9Confident90.2Very high1 Ų141.2 Ų41.21%0.00822%0.218CC..  trans-66.4139.3165.300000110.2L148 G151 K152 I154A134-L148 HydrophobicContact CB-CB 3.9Å; A134-L148 HydrophobicContact CB-CD1 4.15Å; A134-L148 HydrophobicContact CB-CD2 4.19Å; A134-L148 HydrophobicContact CB-CG 4.3Å; A134-G151 PolarHBondContact O-N 3.26Å; A134-K152 PolarHBondContact N-O 3.31Å; A134-I154 HydrophobicContact CB-CG1 4.4Å
135K84.1Confident89.9Confident99 Ų9947.5 Ų47.543%0.4325%0.252SS..SBendtrans-110.3-78178.7-69.9-174174.8-175.10109.1A42 G43 E137 P150A42-K135 PolarHBondContact O-NZ 2.88Å; G43-K135 VanDerWaalsContact CA-NZ 3.27Å; K135-E137 PolarHBondContact N-OE2 2.93Å; K135-P150 WeakPolarHBondContact O-CG 3.33Å
136D86Confident89.6Confident153 Ų15347.6 Ų47.682%0.81825%0.253SS*.SBendtrans-98-12-176-52.9-47.6000112.1T138D136-T138 PolarHBondContact O-N 3.44Å
137E88.3Confident89.4Confident41 Ų4153.2 Ų53.219%0.19228%0.277CS..  trans-72.5128.4-176-58.599.1153.100112.6W31 R35 K135 L148W31-E137 HydrophobicContact CZ2-CG 4.12Å; W31-E137 PolarHBondContact NE1-OE1 3.21Å; W31-E137 VanDerWaalsContact NE1-OE1 3.12Å; R35-E137 IonicContact CZ-OE1 2.79Å; R35-E137 IonicContact NH1-OE1 3.38Å; R35-E137 PolarHBondContact NH1-OE1 2.89Å; R35-E137 IonicContact NH1-OE2 3.88Å; R35-E137 PolarHBondContact NH1-OE2 3.25Å; K135-E137 PolarHBondContact N-OE2 2.93Å; E137-L148 HydrophobicContact CB-CB 4.48Å; E137-L148 HydrophobicContact CB-CD1 3.97Å; E137-L148 CarbonylContact O-C 3.5Å; E137-L148 VanDerWaalsContact O-CB 3.26Å; E137-L148 WeakPolarHBondContact O-CB 3.45Å
138T88.7Confident89.2Confident96 Ų9652.3 Ų52.359%0.58927%0.273SS*.SBendtrans-89.9-20.9175.958.50000113.1D136 K147 L148D136-T138 PolarHBondContact O-N 3.44Å; T138-K147 CarbonylContact O-C 3.6Å; T138-K147 WeakPolarHBondContact O-CA 3.37Å; T138-L148 CarbonylContact C-O 3.44Å; T138-L148 PolarHBondContact O-N 2.79Å
139H91.7Very high88.9Confident80 Ų8056 Ų5637%0.3729%0.287SS..EExtended strand (participates in β ladder)trans-157.7161178.560.5-72.9000110.3A146H139-A146 CarbonylContact C-O 3.53Å; H139-A146 VanDerWaalsContact CA-O 3.28Å; H139-A146 WeakPolarHBondContact CA-O 3.49Å
140V92.6Very high88.5Confident1 Ų159.7 Ų59.71%0.00631%0.312CS..EExtended strand (participates in β ladder)trans-66.8128.5170.21790000108.2A28 W31 G142 Y143 A146 L148 R157 L158 I163A28-V140 HydrophobicContact CB-CG1 4.32Å; W31-V140 HydrophobicContact CE3-CG1 4.32Å; W31-V140 HydrophobicContact CZ3-CG1 4.02Å; W31-V140 HydrophobicContact CZ3-CG2 4.41Å; V140-G142 PolarHBondContact O-N 3.26Å; V140-Y143 HydrophobicContact CG1-CD2 4.15Å; V140-Y143 CarbonylContact O-C 3.53Å; V140-Y143 WeakPolarHBondContact O-CA 3.48Å; V140-Y143 PolarHBondContact O-N 3.22Å; V140-A146 HydrophobicContact CB-CB 3.94Å; V140-A146 HydrophobicContact CG2-CB 3.81Å; V140-A146 PolarHBondContact N-O 2.99Å; V140-L148 HydrophobicContact CG2-CD1 3.96Å; V140-L148 HydrophobicContact CG2-CG 4.2Å; V140-R157 HydrophobicContact CG2-CG 4.45Å; V140-L158 HydrophobicContact CG1-CD2 3.99Å; V140-L158 HydrophobicContact CG2-CD2 4.03Å; V140-I163 HydrophobicContact CG1-CD1 4.34Å
141P92.6Very high88.2Confident33 Ų3357.8 Ų57.821%0.21431%0.306CS..THydrogen-bonded Turntrans-51.2135.1179.2-30.438.6000112E27 A28 W31 Y143E27-P141 HydrophobicContact CB-CB 4.49Å; A28-P141 VanDerWaalsContact CB-O 3.31Å; A28-P141 WeakPolarHBondContact CB-O 3.38Å; W31-P141 HydrophobicContact CB-CB 4.45Å; W31-P141 HydrophobicContact CB-CG 3.84Å; W31-P141 HydrophobicContact CD2-CG 3.86Å; W31-P141 HydrophobicContact CE3-CG 4.41Å; W31-P141 HydrophobicContact CG-CG 3.58Å; P141-Y143 WeakPolarHBondContact O-CD2 3.27Å; P141-Y143 PolarHBondContact O-N 3.43Å
142G89.4Confident88.1Confident21 Ų2157.5 Ų57.522%0.21630%0.302CS..THydrogen-bonded Turntrans77-10.7-174.400000115.8K25 V140K25-G142 VanDerWaalsContact CD-O 3.31Å; K25-G142 WeakPolarHBondContact CD-O 3.5Å; K25-G142 VanDerWaalsContact CE-O 3.31Å; K25-G142 WeakPolarHBondContact CE-O 3Å; K25-G142 PolarHBondContact NZ-O 2.82Å; V140-G142 PolarHBondContact O-N 3.26Å
143Y90.8Very high88Confident51 Ų5157.3 Ų57.320%0.230%0.302CS..EExtended strand (participates in β ladder)trans-126.887.8-178.9-65.1-89.8000112.1T24 K25 A28 V140 P141 N145 A146 I163T24-Y143 WeakPolarHBondContact CA-OH 3.44Å; T24-Y143 HydrophobicContact CG2-CE2 4.41Å; K25-Y143 HydrophobicContact CB-CE2 4.39Å; K25-Y143 HydrophobicContact CD-CE2 4.49Å; K25-Y143 HydrophobicContact CG-CE2 4.41Å; K25-Y143 PolarHBondContact N-OH 3.28Å; A28-Y143 HydrophobicContact CB-CD2 4.19Å; A28-Y143 HydrophobicContact CB-CE2 3.9Å; V140-Y143 HydrophobicContact CG1-CD2 4.15Å; V140-Y143 CarbonylContact O-C 3.53Å; V140-Y143 WeakPolarHBondContact O-CA 3.48Å; V140-Y143 PolarHBondContact O-N 3.22Å; P141-Y143 WeakPolarHBondContact O-CD2 3.27Å; P141-Y143 PolarHBondContact O-N 3.43Å; Y143-N145 PolarHBondContact O-N 3.35Å; Y143-A146 PolarHBondContact O-N 2.94Å; Y143-I163 HydrophobicContact CD1-CD1 3.98Å; Y143-I163 HydrophobicContact CD1-CG1 4.37Å; Y143-I163 HydrophobicContact CD2-CD1 3.77Å; Y143-I163 HydrophobicContact CE1-CD1 4.29Å; Y143-I163 HydrophobicContact CE1-CG1 4.25Å; Y143-I163 HydrophobicContact CE2-CD1 4.1Å; Y143-I163 HydrophobicContact CE2-CG1 4.45Å; Y143-I163 HydrophobicContact CE2-CG2 4.35Å; Y143-I163 HydrophobicContact CG-CD1 3.71Å
144S87Confident88.2Confident88 Ų8854.9 Ų54.962%0.61529%0.292SS*.EExtended strand (participates in β ladder)trans-59.2-28.8176.753.70000113.8A146S144-A146 VanDerWaalsContact C-N 3.27Å; S144-A146 PolarHBondContact O-N 3.07Å
145N88.7Confident88.4Confident135 Ų13555 Ų5572%0.72229%0.293SS*.EExtended strand (participates in β ladder)trans-75.4-14.3178.2-64.1-18.2000113.3Y143 K147 K161Y143-N145 PolarHBondContact O-N 3.35Å; N145-K147 PolarHBondContact O-N 3.14Å; N145-K161 WeakPolarHBondContact O-CE 3.46Å
146A89.6Confident88.5Confident2 Ų254 Ų542%0.01729%0.287CS..EExtended strand (participates in β ladder)trans-98.967.9-179.500000110.7H139 V140 Y143 S144 L148 K161 I163H139-A146 CarbonylContact C-O 3.53Å; H139-A146 VanDerWaalsContact CA-O 3.28Å; H139-A146 WeakPolarHBondContact CA-O 3.49Å; V140-A146 HydrophobicContact CB-CB 3.94Å; V140-A146 HydrophobicContact CG2-CB 3.81Å; V140-A146 PolarHBondContact N-O 2.99Å; Y143-A146 PolarHBondContact O-N 2.94Å; S144-A146 VanDerWaalsContact C-N 3.27Å; S144-A146 PolarHBondContact O-N 3.07Å; A146-L148 PolarHBondContact O-N 2.8Å; A146-K161 HydrophobicContact CB-CG 4.08Å; A146-I163 HydrophobicContact CB-CD1 4.17Å
147K88.6Confident88.7Confident147 Ų14748.8 Ų48.864%0.63926%0.255SS*.EExtended strand (participates in β ladder)trans-62.1133.4-179.3-63.2-175.6179.1-177.50112.5T138 N145 R157T138-K147 CarbonylContact O-C 3.6Å; T138-K147 WeakPolarHBondContact O-CA 3.37Å; N145-K147 PolarHBondContact O-N 3.14Å; K147-R157 PolarHBondContact O-NE 2.56Å; K147-R157 PolarHBondContact O-NH1 2.9Å; K147-R157 PolarHBondContact O-NH2 3.33Å
148L88.9Confident88.9Confident9 Ų947 Ų475%0.04725%0.247CC..  trans-112151.6171.7-68.4173.9000109W31 A134 E137 T138 V140 A146 K152 R157W31-L148 HydrophobicContact CH2-CD1 3.78Å; W31-L148 HydrophobicContact CZ2-CD1 4.02Å; A134-L148 HydrophobicContact CB-CB 3.9Å; A134-L148 HydrophobicContact CB-CD1 4.15Å; A134-L148 HydrophobicContact CB-CD2 4.19Å; A134-L148 HydrophobicContact CB-CG 4.3Å; E137-L148 HydrophobicContact CB-CB 4.48Å; E137-L148 HydrophobicContact CB-CD1 3.97Å; E137-L148 CarbonylContact O-C 3.5Å; E137-L148 VanDerWaalsContact O-CB 3.26Å; E137-L148 WeakPolarHBondContact O-CB 3.45Å; T138-L148 CarbonylContact C-O 3.44Å; T138-L148 PolarHBondContact O-N 2.79Å; V140-L148 HydrophobicContact CG2-CD1 3.96Å; V140-L148 HydrophobicContact CG2-CG 4.2Å; A146-L148 PolarHBondContact O-N 2.8Å; L148-K152 HydrophobicContact CD2-CG 4.49Å; L148-R157 HydrophobicContact CD2-CB 3.86Å; L148-R157 HydrophobicContact CD2-CG 3.78Å
149Y85.3Confident89Confident84 Ų8445.5 Ų45.533%0.32924%0.235SC..  trans-140.5156.3173.353.8-99.6000108.1G151 K152Y149-G151 PolarHBondContact O-N 3.04Å; Y149-K152 HydrophobicContact CD1-CB 4.29Å; Y149-K152 HydrophobicContact CD2-CB 3.87Å; Y149-K152 HydrophobicContact CE1-CB 4.22Å; Y149-K152 HydrophobicContact CE1-CD 4.15Å; Y149-K152 HydrophobicContact CE1-CG 4.12Å; Y149-K152 HydrophobicContact CE2-CB 3.77Å; Y149-K152 HydrophobicContact CE2-CD 4.17Å; Y149-K152 HydrophobicContact CE2-CG 4.34Å; Y149-K152 HydrophobicContact CG-CB 4.13Å; Y149-K152 VanDerWaalsContact O-CB 3.26Å; Y149-K152 WeakPolarHBondContact O-CB 3.46Å; Y149-K152 PolarHBondContact O-N 3.06Å
150P85.3Confident88.8Confident79 Ų7945.2 Ų45.251%0.51324%0.242SC..THydrogen-bonded Turntrans-51.8127.6-178.7-26.633.4000111.7K135 L289K135-P150 WeakPolarHBondContact O-CG 3.33Å; P150-L289 HydrophobicContact CB-CD2 4.12Å
151G81.3Confident88.7Confident11 Ų1150.3 Ų50.311%0.11326%0.264CS..THydrogen-bonded Turntrans82.93.4-178.600000115.5R133 A134 Y149R133-G151 VanDerWaalsContact CD-O 3.32Å; R133-G151 WeakPolarHBondContact CD-O 3.21Å; A134-G151 PolarHBondContact O-N 3.26Å; Y149-G151 PolarHBondContact O-N 3.04Å
152K85.1Confident88.5Confident17 Ų1750.5 Ų50.57%0.07427%0.273CS..  trans-78.7130.9173-172.151.5169176.80111.2R133 A134 L148 Y149 I154R133-K152 WeakPolarHBondContact CA-O 3.01Å; A134-K152 PolarHBondContact N-O 3.31Å; L148-K152 HydrophobicContact CD2-CG 4.49Å; Y149-K152 HydrophobicContact CD1-CB 4.29Å; Y149-K152 HydrophobicContact CD2-CB 3.87Å; Y149-K152 HydrophobicContact CE1-CB 4.22Å; Y149-K152 HydrophobicContact CE1-CD 4.15Å; Y149-K152 HydrophobicContact CE1-CG 4.12Å; Y149-K152 HydrophobicContact CE2-CB 3.77Å; Y149-K152 HydrophobicContact CE2-CD 4.17Å; Y149-K152 HydrophobicContact CE2-CG 4.34Å; Y149-K152 HydrophobicContact CG-CB 4.13Å; Y149-K152 VanDerWaalsContact O-CB 3.26Å; Y149-K152 WeakPolarHBondContact O-CB 3.46Å; Y149-K152 PolarHBondContact O-N 3.06Å; K152-I154 PolarHBondContact O-N 2.79Å
153S88.2Confident88.7Confident4 Ų449.9 Ų49.93%0.02826%0.264CS..BIsolated β-bridgetrans-57.6124.7170.91750000111.5E130 L132 R156 R157E130-S153 PolarHBondContact O-OG 2.91Å; L132-S153 WeakPolarHBondContact O-CA 3.41Å; S153-R156 PolarHBondContact OG-N 2.97Å; S153-R157 PolarHBondContact O-N 2.95Å
154I91.8Very high88.9Confident0 Ų047.5 Ų47.50%026%0.255CS..Hα-helixtrans-67.9-51.6179.7-64.9-179.3000109.9W31 L32 R35 L132 A134 K152 R156 R157 L158W31-I154 HydrophobicContact CH2-CB 4.49Å; W31-I154 HydrophobicContact CH2-CD1 3.87Å; W31-I154 HydrophobicContact CH2-CG1 4.17Å; W31-I154 HydrophobicContact CH2-CG2 3.56Å; W31-I154 HydrophobicContact CZ2-CD1 3.91Å; W31-I154 HydrophobicContact CZ3-CG2 3.86Å; L32-I154 HydrophobicContact CD1-CG2 4.23Å; R35-I154 HydrophobicContact CG-CD1 4.5Å; L132-I154 HydrophobicContact CD2-CB 4.4Å; L132-I154 HydrophobicContact CD2-CD1 4.05Å; L132-I154 HydrophobicContact CG-CD1 4Å; L132-I154 PolarHBondContact O-N 3.39Å; A134-I154 HydrophobicContact CB-CG1 4.4Å; K152-I154 PolarHBondContact O-N 2.79Å; I154-R156 PolarHBondContact O-N 3.49Å; I154-R157 WeakPolarHBondContact O-CB 3.34Å; I154-R157 PolarHBondContact O-N 3.28Å; I154-L158 HydrophobicContact CG2-CD1 3.96Å; I154-L158 HydrophobicContact CG2-CG 4.38Å; I154-L158 WeakPolarHBondContact O-CG 3.08Å; I154-L158 PolarHBondContact O-N 2.92Å
155I92Very high89.1Confident3 Ų347.3 Ų47.32%0.01525%0.246CC..Hα-helixtrans-58.6-44.8-178.9-64.2-60.8000111.5L32 L129 R157 L158 L159 L164L32-I155 HydrophobicContact CD1-CD1 4.47Å; L129-I155 HydrophobicContact CB-CG1 4.19Å; L129-I155 WeakPolarHBondContact O-CG1 3.28Å; I155-R157 VanDerWaalsContact C-N 3.3Å; I155-R157 PolarHBondContact O-N 3.14Å; I155-L158 PolarHBondContact O-N 3.41Å; I155-L159 HydrophobicContact CG2-CD1 4.08Å; I155-L159 WeakPolarHBondContact O-CG 3.28Å; I155-L159 PolarHBondContact O-N 2.93Å; I155-L164 HydrophobicContact CD1-CD2 4.32Å; I155-L164 HydrophobicContact CG2-CD2 3.97Å
156R87.6Confident89.3Confident80 Ų8042.5 Ų42.530%0.30222%0.219SC..Hα-helixtrans-59.9-41.1176.1-176.664.9169.7172.6-3.6112S153 I154 L158 L159 S160 P283 E383S153-R156 PolarHBondContact OG-N 2.97Å; I154-R156 PolarHBondContact O-N 3.49Å; R156-L158 VanDerWaalsContact C-N 3.34Å; R156-L159 PolarHBondContact O-N 2.72Å; R156-S160 WeakPolarHBondContact O-CB 3.28Å; R156-S160 PolarHBondContact O-N 2.91Å; R156-S160 PolarHBondContact O-OG 2.85Å; R156-P283 HydrophobicContact CB-CB 3.76Å; R156-P283 WeakPolarHBondContact CB-O 3.46Å; R156-P283 HydrophobicContact CG-CB 4.24Å; R156-P283 VanDerWaalsContact CG-O 3.31Å; R156-P283 WeakPolarHBondContact CG-O 3.39Å; R156-E383 IonicContact CZ-OE1 3.14Å; R156-E383 IonicContact NH2-OE1 3.34Å; R156-E383 PolarHBondContact NH2-OE1 3.34Å; R156-E383 IonicContact NH2-OE2 3.04Å
157R89.6Confident89.5Confident42 Ų4243.9 Ų43.916%0.15823%0.226CC..Hα-helixtrans-63.5-44.4179.7-176.259.459.7149.710.1110.6V140 K147 L148 S153 I154 I155 S160 K161V140-R157 HydrophobicContact CG2-CG 4.45Å; K147-R157 PolarHBondContact O-NE 2.56Å; K147-R157 PolarHBondContact O-NH1 2.9Å; K147-R157 PolarHBondContact O-NH2 3.33Å; L148-R157 HydrophobicContact CD2-CB 3.86Å; L148-R157 HydrophobicContact CD2-CG 3.78Å; S153-R157 PolarHBondContact O-N 2.95Å; I154-R157 WeakPolarHBondContact O-CB 3.34Å; I154-R157 PolarHBondContact O-N 3.28Å; I155-R157 VanDerWaalsContact C-N 3.3Å; I155-R157 PolarHBondContact O-N 3.14Å; R157-S160 PolarHBondContact O-N 3.41Å; R157-S160 PolarHBondContact O-OG 3.16Å; R157-K161 PolarHBondContact O-N 3.43Å; R157-K161 VanDerWaalsContact O-N 3.11Å
158L92.7Very high89.8Confident4 Ų437.1 Ų37.12%0.02120%0.196CC..Hα-helixtrans-62.2-43.6178.4-65.2173.7000111.9L32 V140 I154 I155 R156 K161 G162 I163 L164L32-L158 HydrophobicContact CD1-CD1 3.82Å; L32-L158 HydrophobicContact CD2-CD1 3.84Å; L32-L158 HydrophobicContact CG-CD1 4.41Å; V140-L158 HydrophobicContact CG1-CD2 3.99Å; V140-L158 HydrophobicContact CG2-CD2 4.03Å; I154-L158 HydrophobicContact CG2-CD1 3.96Å; I154-L158 HydrophobicContact CG2-CG 4.38Å; I154-L158 WeakPolarHBondContact O-CG 3.08Å; I154-L158 PolarHBondContact O-N 2.92Å; I155-L158 PolarHBondContact O-N 3.41Å; R156-L158 VanDerWaalsContact C-N 3.34Å; L158-K161 PolarHBondContact O-N 2.84Å; L158-G162 PolarHBondContact O-N 3Å; L158-I163 HydrophobicContact CB-CB 4.5Å; L158-I163 HydrophobicContact CD2-CB 3.94Å; L158-I163 HydrophobicContact CD2-CD1 3.96Å; L158-I163 HydrophobicContact CD2-CG2 3.89Å; L158-I163 PolarHBondContact O-N 3.08Å; L158-L164 HydrophobicContact CB-CB 3.67Å; L158-L164 PolarHBondContact O-N 2.9Å
159L90.9Very high90.2Very high65 Ų6536.8 Ų36.834%0.3420%0.195SC..Hα-helixtrans-61.5-49.9174.1-70.1168.7000111.7I155 R156 K161 G162 L164I155-L159 HydrophobicContact CG2-CD1 4.08Å; I155-L159 WeakPolarHBondContact O-CG 3.28Å; I155-L159 PolarHBondContact O-N 2.93Å; R156-L159 PolarHBondContact O-N 2.72Å; L159-K161 PolarHBondContact O-N 3.44Å; L159-K161 VanDerWaalsContact O-N 3.16Å; L159-G162 PolarHBondContact O-N 3.44Å; L159-L164 HydrophobicContact CD2-CB 4.17Å; L159-L164 HydrophobicContact CD2-CD2 3.81Å; L159-L164 HydrophobicContact CD2-CG 3.84Å; L159-L164 HydrophobicContact CG-CB 4.47Å; L159-L164 HydrophobicContact CG-CD2 3.95Å; L159-L164 HydrophobicContact CG-CG 4.38Å
160S87.1Confident90.6Very high74 Ų7433 Ų3352%0.51718%0.18SC..Hα-helixtrans-63.8-24.2-17770.70000114.2R156 R157R156-S160 WeakPolarHBondContact O-CB 3.28Å; R156-S160 PolarHBondContact O-N 2.91Å; R156-S160 PolarHBondContact O-OG 2.85Å; R157-S160 PolarHBondContact O-N 3.41Å; R157-S160 PolarHBondContact O-OG 3.16Å
161K89.9Confident90.9Very high107 Ų10729.9 Ų29.947%0.46516%0.159SC..THydrogen-bonded Turntrans-99.32.3178.3-68.4-61.1-174.4-177.80112.9N145 A146 R157 L158 L159 I163N145-K161 WeakPolarHBondContact O-CE 3.46Å; A146-K161 HydrophobicContact CB-CG 4.08Å; R157-K161 PolarHBondContact O-N 3.43Å; R157-K161 VanDerWaalsContact O-N 3.11Å; L158-K161 PolarHBondContact O-N 2.84Å; L159-K161 PolarHBondContact O-N 3.44Å; L159-K161 VanDerWaalsContact O-N 3.16Å; K161-I163 HydrophobicContact CB-CD1 4.26Å; K161-I163 HydrophobicContact CB-CG1 4.24Å; K161-I163 PolarHBondContact O-N 3.35Å
162G89.6Confident91.3Very high38 Ų3832.4 Ų32.439%0.39217%0.167SC..THydrogen-bonded Turntrans66.718.7179.600000114.2L158 L159L158-G162 PolarHBondContact O-N 3Å; L159-G162 PolarHBondContact O-N 3.44Å
163I93.6Very high91.3Very high7 Ų735.6 Ų35.64%0.03618%0.181CC..SBendtrans-78.2-45174.9-58.2170.8000109L20 I21 T24 V140 Y143 A146 L158 K161L20-I163 WeakPolarHBondContact CA-O 3.49Å; I21-I163 PolarHBondContact N-O 2.85Å; T24-I163 HydrophobicContact CG2-CG2 4Å; V140-I163 HydrophobicContact CG1-CD1 4.34Å; Y143-I163 HydrophobicContact CD1-CD1 3.98Å; Y143-I163 HydrophobicContact CD1-CG1 4.37Å; Y143-I163 HydrophobicContact CD2-CD1 3.77Å; Y143-I163 HydrophobicContact CE1-CD1 4.29Å; Y143-I163 HydrophobicContact CE1-CG1 4.25Å; Y143-I163 HydrophobicContact CE2-CD1 4.1Å; Y143-I163 HydrophobicContact CE2-CG1 4.45Å; Y143-I163 HydrophobicContact CE2-CG2 4.35Å; Y143-I163 HydrophobicContact CG-CD1 3.71Å; A146-I163 HydrophobicContact CB-CD1 4.17Å; L158-I163 HydrophobicContact CB-CB 4.5Å; L158-I163 HydrophobicContact CD2-CB 3.94Å; L158-I163 HydrophobicContact CD2-CD1 3.96Å; L158-I163 HydrophobicContact CD2-CG2 3.89Å; L158-I163 PolarHBondContact O-N 3.08Å; K161-I163 HydrophobicContact CB-CD1 4.26Å; K161-I163 HydrophobicContact CB-CG1 4.24Å; K161-I163 PolarHBondContact O-N 3.35Å
164L93.5Very high91.2Very high2 Ų240.4 Ų40.41%0.0120%0.203CC..EExtended strand (participates in β ladder)trans-92.8118.8166.3-177.668.8000107.3L18 E19 L20 I155 L158 L159L18-L164 HydrophobicContact CB-CD1 4.1Å; L18-L164 HydrophobicContact CD2-CD1 4.18Å; L18-L164 HydrophobicContact CD2-CD2 4.42Å; E19-L164 WeakPolarHBondContact O-CD1 3.34Å; L20-L164 HydrophobicContact CD2-CB 4.02Å; L20-L164 HydrophobicContact CD2-CD1 3.66Å; L20-L164 HydrophobicContact CD2-CG 4.46Å; L20-L164 HydrophobicContact CG-CD1 4.5Å; I155-L164 HydrophobicContact CD1-CD2 4.32Å; I155-L164 HydrophobicContact CG2-CD2 3.97Å; L158-L164 HydrophobicContact CB-CB 3.67Å; L158-L164 PolarHBondContact O-N 2.9Å; L159-L164 HydrophobicContact CD2-CB 4.17Å; L159-L164 HydrophobicContact CD2-CD2 3.81Å; L159-L164 HydrophobicContact CD2-CG 3.84Å; L159-L164 HydrophobicContact CG-CB 4.47Å; L159-L164 HydrophobicContact CG-CD2 3.95Å; L159-L164 HydrophobicContact CG-CG 4.38Å
165I91.8Very high91.1Very high84 Ų8443.3 Ų43.343%0.43122%0.217SC..EExtended strand (participates in β ladder)trans-74.5-53.2178.1-61177.7000108.6E19 I21E19-I165 HydrophobicContact CG-CB 4.39Å; E19-I165 HydrophobicContact CG-CD1 4.26Å; E19-I165 WeakPolarHBondContact O-CB 3.42Å; E19-I165 PolarHBondContact O-N 3.47Å; I21-I165 HydrophobicContact CB-CD1 4.31Å; I21-I165 HydrophobicContact CB-CG1 4.34Å
166Q92.5Very high91Very high34 Ų3444 Ų4416%0.15922%0.221CC..EExtended strand (participates in β ladder)trans-156.3157-176.156.3-177.54.500112.8E19 F168 A485E19-Q166 HydrophobicContact CB-CG 3.85Å; E19-Q166 PolarHBondContact N-O 2.85Å; E19-Q166 PolarHBondContact O-N 2.99Å; E19-Q166 WeakPolarHBondContact OE2-CG 3.35Å; E19-Q166 PolarHBondContact OE2-NE2 3.26Å; Q166-F168 HydrophobicContact CG-CD1 4.08Å; Q166-F168 HydrophobicContact CG-CE1 4.28Å; Q166-A485 PolarHBondContact NE2-O 2.83Å
167M94.6Very high91.1Very high30 Ų3047.6 Ų47.615%0.14824%0.238CC..EExtended strand (participates in β ladder)trans-129.5124.4170.9174.3-178.376.600106.9V16 V17 L18 K126 L129 E130 F544V16-M167 HydrophobicContact CG1-CG 3.8Å; V17-M167 WeakPolarHBondContact O-CA 3.37Å; L18-M167 HydrophobicContact CD2-CB 3.85Å; L18-M167 HydrophobicContact CD2-CG 3.65Å; L18-M167 HydrophobicContact CD2-SD 4.05Å; K126-M167 HydrophobicContact CB-CE 4.47Å; K126-M167 HydrophobicContact CG-CE 3.95Å; L129-M167 HydrophobicContact CB-SD 4.36Å; L129-M167 HydrophobicContact CD1-SD 3.86Å; E130-M167 HydrophobicContact CG-CE 4.44Å; M167-F544 HydrophobicContact CE-CE2 3.84Å; M167-F544 HydrophobicContact CE-CZ 3.98Å; M167-F544 HydrophobicContact CG-CE2 4.14Å; M167-F544 HydrophobicContact CG-CZ 3.88Å; M167-F544 WeakPolarHBondContact O-CE2 3.4Å; M167-F544 HydrophobicContact SD-CZ 4.4Å
168F95.1Very high91.1Very high6 Ų654 Ų543%0.02626%0.263CS..EExtended strand (participates in β ladder)trans-145.8147.8-178.864.1-88.4000112.2V17 Q166 L170 E484 A485 K541V17-F168 HydrophobicContact CB-CD1 4.34Å; V17-F168 HydrophobicContact CB-CD2 4.41Å; V17-F168 HydrophobicContact CB-CE1 3.89Å; V17-F168 HydrophobicContact CB-CE2 3.97Å; V17-F168 HydrophobicContact CB-CZ 3.69Å; V17-F168 HydrophobicContact CG1-CE1 3.91Å; V17-F168 HydrophobicContact CG1-CZ 3.79Å; V17-F168 HydrophobicContact CG2-CE2 3.94Å; V17-F168 HydrophobicContact CG2-CZ 4.01Å; V17-F168 PolarHBondContact N-O 3.12Å; V17-F168 PolarHBondContact O-N 3.03Å; V17-F168 VanDerWaalsContact O-N 3.12Å; Q166-F168 HydrophobicContact CG-CD1 4.08Å; Q166-F168 HydrophobicContact CG-CE1 4.28Å; F168-L170 HydrophobicContact CE2-CD2 4.27Å; F168-E484 HydrophobicContact CE2-CB 3.89Å; F168-A485 HydrophobicContact CE1-CB 4.04Å; F168-A485 HydrophobicContact CZ-CB 3.83Å; F168-K541 HydrophobicContact CB-CD 4.28Å; F168-K541 HydrophobicContact CG-CD 4.22Å
169P96.1Very high91Very high1 Ų154.1 Ų54.11%0.00626%0.263CS..EExtended strand (participates in β ladder)trans-79148.3174.428.9-26.3000111.5Q122 R542 F544Q122-P169 HydrophobicContact CB-CB 4.07Å; Q122-P169 HydrophobicContact CG-CB 3.94Å; P169-R542 WeakPolarHBondContact CD-O 3.48Å; P169-R542 HydrophobicContact CG-CB 4.02Å; P169-R542 HydrophobicContact CG-CG 4.07Å; P169-R542 WeakPolarHBondContact CG-O 3.38Å; P169-F544 HydrophobicContact CB-CD1 4.11Å; P169-F544 HydrophobicContact CB-CE1 3.89Å; P169-F544 HydrophobicContact CB-CZ 4.43Å; P169-F544 HydrophobicContact CG-CD1 3.8Å; P169-F544 HydrophobicContact CG-CD2 4.37Å; P169-F544 HydrophobicContact CG-CE1 3.9Å; P169-F544 HydrophobicContact CG-CE2 4.49Å; P169-F544 HydrophobicContact CG-CG 4.04Å; P169-F544 HydrophobicContact CG-CZ 4.25Å
170L93.6Very high90.9Very high5 Ų551.1 Ų51.13%0.02625%0.247CC..PPolyproline II helixtrans-80145.3176.8-74.4171.6000112.8P14 L15 V17 L68 Q122 F168 V481 R542P14-L170 HydrophobicContact CB-CD1 4.05Å; P14-L170 HydrophobicContact CG-CD1 4.24Å; L15-L170 PolarHBondContact O-N 3.04Å; V17-L170 HydrophobicContact CG2-CD1 3.95Å; V17-L170 HydrophobicContact CG2-CD2 3.64Å; V17-L170 HydrophobicContact CG2-CG 3.66Å; L68-L170 HydrophobicContact CD2-CD1 4.49Å; Q122-L170 PolarHBondContact NE2-O 2.98Å; F168-L170 HydrophobicContact CE2-CD2 4.27Å; L170-V481 HydrophobicContact CD1-CG2 4.24Å; L170-V481 HydrophobicContact CD2-CG2 3.94Å; L170-R542 WeakPolarHBondContact O-CD 3.5Å; L170-R542 PolarHBondContact O-NH1 3.36Å
171H91.4Very high90.9Very high13 Ų1353.1 Ų53.16%0.0625%0.247CC..PPolyproline II helixtrans-76.2135.1167.5-82.8-73.3000112.3Y200 Q480 E484 R542H171-Y200 AromaticContact ND1-CE1 3.59Å; H171-Y200 AromaticContact ND1-CZ 3.66Å; H171-Y200 PolarHBondContact ND1-OH 3.29Å; H171-Q480 PolarHBondContact O-NE2 2.99Å; H171-E484 IonicContact CD2-OE2 3.6Å; H171-E484 PolarHBondContact N-OE2 2.78Å; H171-R542 WeakPolarHBondContact NE2-CA 3.24Å; H171-R542 PolarHBondContact NE2-N 3.36Å
172H89.6Confident90.7Very high65 Ų6549.7 Ų49.730%0.30124%0.237SC..  trans-86.9111.6162.2-163.6-54.3000110M118 E174 E175 L176 Y200M118-H172 HydrophobicContact CE-CB 4.32Å; M118-H172 HydrophobicContact SD-CB 3.66Å; H172-E174 PolarHBondContact ND1-N 2.79Å; H172-E174 PolarHBondContact O-N 3.19Å; H172-E175 HydrophobicContact CB-CB 4.23Å; H172-E175 HydrophobicContact CB-CG 4.37Å; H172-L176 VanDerWaalsContact O-CB 3.25Å; H172-L176 WeakPolarHBondContact O-CB 3.37Å; H172-L176 PolarHBondContact O-N 2.86Å; H172-Y200 HydrophobicContact CB-CE2 4.3Å; H172-Y200 PolarHBondContact N-OH 3.25Å; H172-Y200 VanDerWaalsContact N-OH 3.12Å; H172-Y200 PolarHBondContact O-OH 2.78Å
173K85.6Confident90.5Very high84 Ų8448.5 Ų48.537%0.36522%0.22SC..Hα-helixtrans-62.8-41.6-173.5-72.8175.3177.5145.20113.5K177 Q480K173-K177 VanDerWaalsContact O-CB 3.3Å; K173-K177 WeakPolarHBondContact O-CB 3.19Å; K173-K177 PolarHBondContact O-N 2.82Å; K173-Q480 VanDerWaalsContact CE-CD 3.46Å; K173-Q480 VanDerWaalsContact CE-OE1 3.24Å
174E87.1Confident90Very high104 Ų10450 Ų5049%0.48623%0.226SC..Hα-helixtrans-67.9-50.6-177.8-56.1-164.515100112.8H172 L176 K177 R178H172-E174 PolarHBondContact ND1-N 2.79Å; H172-E174 PolarHBondContact O-N 3.19Å; E174-L176 VanDerWaalsContact C-N 3.35Å; E174-L176 PolarHBondContact O-N 3.25Å; E174-K177 WeakPolarHBondContact O-CB 3.37Å; E174-K177 PolarHBondContact O-N 3.4Å; E174-R178 WeakPolarHBondContact O-CG 3.38Å; E174-R178 PolarHBondContact O-N 2.48Å
175E88.6Confident89Confident61 Ų6154.8 Ų54.829%0.28525%0.247SC..Hα-helixtrans-58.2-45.8175.1-68.1-178.7-179.500111.6H172 K177 R178 L179 Y200H172-E175 HydrophobicContact CB-CB 4.23Å; H172-E175 HydrophobicContact CB-CG 4.37Å; E175-K177 VanDerWaalsContact C-N 3.26Å; E175-K177 PolarHBondContact O-N 2.96Å; E175-R178 WeakPolarHBondContact O-CB 3.49Å; E175-R178 PolarHBondContact O-N 2.66Å; E175-R178 VanDerWaalsContact O-N 3.1Å; E175-L179 WeakPolarHBondContact O-CB 3.41Å; E175-L179 PolarHBondContact O-N 2.87Å; E175-Y200 HydrophobicContact CB-CD2 3.97Å; E175-Y200 HydrophobicContact CB-CE2 3.79Å
176L90.6Very high87.8Confident19 Ų1955.4 Ų55.410%0.09925%0.246CC..Hα-helixtrans-60.9-37.6177-171.359.1000112.1H172 E174 S180 Y200 Y201 C537H172-L176 VanDerWaalsContact O-CB 3.25Å; H172-L176 WeakPolarHBondContact O-CB 3.37Å; H172-L176 PolarHBondContact O-N 2.86Å; E174-L176 VanDerWaalsContact C-N 3.35Å; E174-L176 PolarHBondContact O-N 3.25Å; L176-S180 VanDerWaalsContact O-CB 3.26Å; L176-S180 WeakPolarHBondContact O-CB 3.44Å; L176-S180 PolarHBondContact O-N 2.96Å; L176-S180 PolarHBondContact O-OG 3.02Å; L176-Y200 HydrophobicContact CB-CE2 4.23Å; L176-Y200 WeakPolarHBondContact CB-OH 3.25Å; L176-Y200 HydrophobicContact CD1-CD1 4.4Å; L176-Y200 HydrophobicContact CD1-CE1 3.75Å; L176-Y201 WeakPolarHBondContact CD1-OH 3.4Å; L176-C537 HydrophobicContact CD1-CB 4.18Å; L176-C537 WeakPolarHBondContact CD2-O 3.37Å
177K88.9Confident86.4Confident154 Ų15462.2 Ų62.267%0.6728%0.276SS*.Hα-helixtrans-66.4-40.5176.5-172.8179.9179-175.30111.1K173 E174 E175 S180 F181K173-K177 VanDerWaalsContact O-CB 3.3Å; K173-K177 WeakPolarHBondContact O-CB 3.19Å; K173-K177 PolarHBondContact O-N 2.82Å; E174-K177 WeakPolarHBondContact O-CB 3.37Å; E174-K177 PolarHBondContact O-N 3.4Å; E175-K177 VanDerWaalsContact C-N 3.26Å; E175-K177 PolarHBondContact O-N 2.96Å; K177-S180 PolarHBondContact O-OG 2.98Å; K177-F181 PolarHBondContact O-N 3.28Å
178R90Very high84.9Confident177 Ų17767.3 Ų67.367%0.66830%0.297SS*.Hα-helixtrans-63.3-50.9174.7-67.7177.5-170.9173.76.5110.6E174 E175 S180 F181 S182E174-R178 WeakPolarHBondContact O-CG 3.38Å; E174-R178 PolarHBondContact O-N 2.48Å; E175-R178 WeakPolarHBondContact O-CB 3.49Å; E175-R178 PolarHBondContact O-N 2.66Å; E175-R178 VanDerWaalsContact O-N 3.1Å; R178-S180 PolarHBondContact O-N 2.75Å; R178-F181 WeakPolarHBondContact O-CB 3.48Å; R178-F181 PolarHBondContact O-N 3.31Å; R178-S182 PolarHBondContact O-N 3.17Å; R178-S182 VanDerWaalsContact O-N 3.16Å
179L91.1Very high83.4Confident6 Ų674.2 Ų74.23%0.03133%0.333CS..Hα-helixtrans-58.5-45.7177.3179.762.6000111.7E175 F181 S182 W183 P193 E196 I197 Y200 Y201E175-L179 WeakPolarHBondContact O-CB 3.41Å; E175-L179 PolarHBondContact O-N 2.87Å; L179-F181 PolarHBondContact O-N 3.03Å; L179-F181 VanDerWaalsContact O-N 3.1Å; L179-S182 PolarHBondContact O-N 3.39Å; L179-S182 PolarHBondContact O-OG 3.48Å; L179-W183 HydrophobicContact CD1-CB 4.46Å; L179-W183 HydrophobicContact CD1-CE3 4.24Å; L179-W183 HydrophobicContact CD2-CE3 4.1Å; L179-W183 HydrophobicContact CD2-CZ3 4.19Å; L179-W183 HydrophobicContact CG-CE3 3.92Å; L179-W183 WeakPolarHBondContact O-CB 3.48Å; L179-W183 PolarHBondContact O-N 3.47Å; L179-P193 HydrophobicContact CD1-CG 4.38Å; L179-E196 HydrophobicContact CD1-CB 3.68Å; L179-I197 HydrophobicContact CD1-CG1 4.1Å; L179-Y200 HydrophobicContact CD2-CD1 4.24Å; L179-Y200 HydrophobicContact CD2-CG 4.04Å; L179-Y201 HydrophobicContact CD2-CD2 4.19Å; L179-Y201 HydrophobicContact CD2-CE2 3.8Å
180S88.6Confident82Confident2 Ų277.5 Ų77.51%0.01436%0.356CS..Hα-helixtrans-59.1-28.7177.674.10000113.1L176 K177 R178 Y184 K185L176-S180 VanDerWaalsContact O-CB 3.26Å; L176-S180 WeakPolarHBondContact O-CB 3.44Å; L176-S180 PolarHBondContact O-N 2.96Å; L176-S180 PolarHBondContact O-OG 3.02Å; K177-S180 PolarHBondContact O-OG 2.98Å; R178-S180 PolarHBondContact O-N 2.75Å; S180-Y184 PolarHBondContact O-N 3.48Å; S180-K185 VanDerWaalsContact O-CG 3.32Å; S180-K185 WeakPolarHBondContact O-CG 3.41Å; S180-K185 PolarHBondContact O-N 2.95Å; S180-K185 PolarHBondContact OG-NZ 3.24Å
181F86.4Confident81.4Confident116 Ų11683.4 Ų83.451%0.50939%0.387SS..Hα-helixtrans-81.2-36.6-179.4-173.1-101.9000112.8K177 R178 L179 K185K177-F181 PolarHBondContact O-N 3.28Å; R178-F181 WeakPolarHBondContact O-CB 3.48Å; R178-F181 PolarHBondContact O-N 3.31Å; L179-F181 PolarHBondContact O-N 3.03Å; L179-F181 VanDerWaalsContact O-N 3.1Å; F181-K185 HydrophobicContact CD2-CB 4.33Å; F181-K185 HydrophobicContact CD2-CD 4.35Å
182S86.1Confident81.3Confident36 Ų3683.6 Ų83.625%0.25239%0.388SS..Hα-helixtrans-73.9-36.4172.952.70000111.9R178 L179 E196R178-S182 PolarHBondContact O-N 3.17Å; R178-S182 VanDerWaalsContact O-N 3.16Å; L179-S182 PolarHBondContact O-N 3.39Å; L179-S182 PolarHBondContact O-OG 3.48Å; S182-E196 WeakPolarHBondContact CB-OE2 3.41Å; S182-E196 PolarHBondContact OG-OE2 3.42Å
183W86.2Confident81.5Confident12 Ų1281.8 Ų81.85%0.04538%0.382CS..Hα-helixtrans-82.8-58.2-167.2-164.45.3000114.8L179 P193 I197 Y201 F209 A533 M536L179-W183 HydrophobicContact CD1-CB 4.46Å; L179-W183 HydrophobicContact CD1-CE3 4.24Å; L179-W183 HydrophobicContact CD2-CE3 4.1Å; L179-W183 HydrophobicContact CD2-CZ3 4.19Å; L179-W183 HydrophobicContact CG-CE3 3.92Å; L179-W183 WeakPolarHBondContact O-CB 3.48Å; L179-W183 PolarHBondContact O-N 3.47Å; W183-P193 HydrophobicContact CB-CG 4.16Å; W183-P193 HydrophobicContact CG-CG 4.34Å; W183-I197 HydrophobicContact CD2-CD1 4Å; W183-I197 HydrophobicContact CD2-CG1 3.97Å; W183-I197 HydrophobicContact CE3-CG1 4.22Å; W183-I197 HydrophobicContact CG-CD1 4.42Å; W183-I197 HydrophobicContact CH2-CD1 4.21Å; W183-I197 HydrophobicContact CH2-CG1 3.99Å; W183-I197 HydrophobicContact CH2-CG2 3.98Å; W183-I197 HydrophobicContact CZ2-CD1 3.43Å; W183-I197 VanDerWaalsContact CZ2-CD1 3.43Å; W183-I197 HydrophobicContact CZ2-CG1 3.72Å; W183-I197 HydrophobicContact CZ2-CG2 4.14Å; W183-I197 HydrophobicContact CZ3-CG1 4.25Å; W183-Y201 HydrophobicContact CH2-CD2 4.47Å; W183-Y201 HydrophobicContact CH2-CE2 4.35Å; W183-Y201 HydrophobicContact CZ3-CD2 4.27Å; W183-Y201 AromaticContact CZ3-CE2 3.79Å; W183-Y201 HydrophobicContact CZ3-CE2 3.79Å; W183-F209 AromaticContact CH2-CD2 3.95Å; W183-F209 HydrophobicContact CH2-CD2 3.95Å; W183-F209 HydrophobicContact CH2-CE1 4.19Å; W183-F209 AromaticContact CH2-CE2 3.48Å; W183-F209 HydrophobicContact CH2-CE2 3.48Å; W183-F209 VanDerWaalsContact CH2-CE2 3.48Å; W183-F209 HydrophobicContact CH2-CG 4.5Å; W183-F209 AromaticContact CH2-CZ 3.6Å; W183-F209 HydrophobicContact CH2-CZ 3.6Å; W183-F209 AromaticContact CZ2-CD1 3.61Å; W183-F209 HydrophobicContact CZ2-CD1 3.61Å; W183-F209 AromaticContact CZ2-CD2 3.55Å; W183-F209 HydrophobicContact CZ2-CD2 3.55Å; W183-F209 AromaticContact CZ2-CE1 3.44Å; W183-F209 HydrophobicContact CZ2-CE1 3.44Å; W183-F209 VanDerWaalsContact CZ2-CE1 3.44Å; W183-F209 AromaticContact CZ2-CE2 3.4Å; W183-F209 HydrophobicContact CZ2-CE2 3.4Å; W183-F209 AromaticContact CZ2-CG 3.65Å; W183-F209 HydrophobicContact CZ2-CG 3.65Å; W183-F209 AromaticContact CZ2-CZ 3.33Å; W183-F209 HydrophobicContact CZ2-CZ 3.33Å; W183-A533 HydrophobicContact CD2-CB 3.62Å; W183-A533 HydrophobicContact CE3-CB 4.04Å; W183-A533 HydrophobicContact CG-CB 4.02Å; W183-A533 HydrophobicContact CH2-CB 4.33Å; W183-A533 HydrophobicContact CZ2-CB 3.93Å; W183-A533 HydrophobicContact CZ3-CB 4.36Å; W183-M536 HydrophobicContact CH2-CB 4.49Å
184Y82.1Confident81.9Confident39 Ų3979 Ų7915%0.15337%0.371CS..THydrogen-bonded Turntrans-125.4-17.5-170.976.9-97000114.9S180 A533 F534 C537 H538S180-Y184 PolarHBondContact O-N 3.48Å; Y184-A533 HydrophobicContact CD1-CB 4.18Å; Y184-A533 HydrophobicContact CG-CB 4.41Å; Y184-F534 HydrophobicContact CE2-CD2 4.12Å; Y184-C537 HydrophobicContact CE1-CB 4.22Å; Y184-H538 PolarHBondContact OH-CD2 3.12Å; Y184-H538 VanDerWaalsContact OH-CD2 3.27Å; Y184-H538 PolarHBondContact OH-NE2 2.81Å
185K72.6Confident82.1Confident103 Ų10377.9 Ų77.945%0.44837%0.368SS..SBendtrans-77.8-20.3-178.2-72.3173.8178.71580114.1S180 F181S180-K185 VanDerWaalsContact O-CG 3.32Å; S180-K185 WeakPolarHBondContact O-CG 3.41Å; S180-K185 PolarHBondContact O-N 2.95Å; S180-K185 PolarHBondContact OG-NZ 3.24Å; F181-K185 HydrophobicContact CD2-CB 4.33Å; F181-K185 HydrophobicContact CD2-CD 4.35Å
186K67.6Low82.4Confident97 Ų9779.5 Ų79.542%0.42238%0.376SS..SBendtrans-93.5106.8170.8-71.9178.5-177.3172.20107.5K188K186-K188 PolarHBondContact O-N 2.93Å
187F63Low82.5Confident176 Ų17678.6 Ų78.677%0.77237%0.371SS*.  trans-71.381.7169.3-162.3-94.2000108.5Y530F187-Y530 HydrophobicContact CD2-CE2 4.47Å; F187-Y530 HydrophobicContact CE2-CE2 4.23Å
188K62Low82.8Confident138 Ų13873.5 Ų73.560%0.635%0.348SS*.  trans-129.6136.5173-73.7-169.1175.8-169.60106.7K186 S190 Y530K186-K188 PolarHBondContact O-N 2.93Å; K188-S190 PolarHBondContact O-N 3.03Å; K188-Y530 PolarHBondContact O-OH 3.34Å
189L64.4Low82.9Confident151 Ų15169.3 Ų69.379%0.79134%0.336SS*.  trans-72.456.4168.1-14791.1000109.2
190S65.5Low83.1Confident70 Ų7069.3 Ų69.349%0.4934%0.335SS..PPolyproline II helixtrans-103.3150.8176.751.90000109.3K188K188-S190 PolarHBondContact O-N 3.03Å
191L82.7Confident83.4Confident128 Ų12869.2 Ų69.267%0.6734%0.335SS*.PPolyproline II helixtrans-53.6139.5171.4-59.6170.5000110.2E213 F217L191-E213 WeakPolarHBondContact CA-OE2 3.48Å; L191-E213 WeakPolarHBondContact CD2-OE1 3.34Å; L191-F217 HydrophobicContact CD2-CE2 4.14Å
192Q89.6Confident83.7Confident18 Ų1863.8 Ų63.88%0.08431%0.311CS..PPolyproline II helixtrans-64.4144.8177.8-70.7-172.368.900110.1L194 I197 F209 E213 V529Q192-L194 HydrophobicContact CB-CD2 4.1Å; Q192-L194 PolarHBondContact O-N 3.49Å; Q192-I197 HydrophobicContact CB-CD1 4.47Å; Q192-F209 PolarHBondContact NE2-O 2.91Å; Q192-E213 VanDerWaalsContact CB-OE2 3.31Å; Q192-E213 WeakPolarHBondContact CB-OE2 3.49Å; Q192-E213 WeakPolarHBondContact CG-OE2 3.36Å; Q192-E213 PolarHBondContact N-OE2 3.3Å; Q192-V529 HydrophobicContact CG-CG1 4.09Å
193P92.8Very high84.1Confident27 Ų2762.8 Ų62.818%0.17530%0.303CS..  trans-77.967.9179.233.9-36.1000110.9L179 W183 D195 E196 I197L179-P193 HydrophobicContact CD1-CG 4.38Å; W183-P193 HydrophobicContact CB-CG 4.16Å; W183-P193 HydrophobicContact CG-CG 4.34Å; P193-D195 VanDerWaalsContact C-N 3.28Å; P193-D195 PolarHBondContact O-N 2.6Å; P193-E196 HydrophobicContact CB-CB 4.09Å; P193-E196 HydrophobicContact CB-CG 4.04Å; P193-E196 PolarHBondContact O-N 3.04Å; P193-I197 HydrophobicContact CG-CD1 4.45Å; P193-I197 HydrophobicContact CG-CG1 4.49Å; P193-I197 WeakPolarHBondContact O-CG1 3.45Å; P193-I197 PolarHBondContact O-N 3.21Å
194L93.3Very high84.3Confident24 Ų2462.8 Ų62.813%0.12631%0.306CS..Hα-helixtrans-55.8-39.3-173-62.4-178.6000113.1Q192 I197 R198 F209 L265 W269Q192-L194 HydrophobicContact CB-CD2 4.1Å; Q192-L194 PolarHBondContact O-N 3.49Å; L194-I197 HydrophobicContact CD2-CD1 4.38Å; L194-I197 PolarHBondContact O-N 3.27Å; L194-R198 VanDerWaalsContact O-CB 3.24Å; L194-R198 WeakPolarHBondContact O-CB 3.45Å; L194-R198 PolarHBondContact O-N 3.07Å; L194-F209 HydrophobicContact CD2-CB 4.26Å; L194-L265 HydrophobicContact CD1-CD1 4.37Å; L194-L265 HydrophobicContact CD1-CD2 4.46Å; L194-W269 HydrophobicContact CB-CZ2 4.34Å
195D92.6Very high84.9Confident81 Ų8161.4 Ų61.443%0.43330%0.301SS..Hα-helixtrans-69.8-33.4178.7-68.4-40.6000112.5P193 H199 W269P193-D195 VanDerWaalsContact C-N 3.28Å; P193-D195 PolarHBondContact O-N 2.6Å; D195-H199 WeakPolarHBondContact O-CB 3.47Å; D195-H199 PolarHBondContact O-N 3.2Å; D195-W269 PolarHBondContact OD1-NE1 3.07Å
196E93.3Very high85.9Confident96 Ų9656.5 Ų56.545%0.44928%0.28SS..Hα-helixtrans-71.4-40.9174-58.8-179.8-169.100111L179 S182 P193 R198 H199 Y200L179-E196 HydrophobicContact CD1-CB 3.68Å; S182-E196 WeakPolarHBondContact CB-OE2 3.41Å; S182-E196 PolarHBondContact OG-OE2 3.42Å; P193-E196 HydrophobicContact CB-CB 4.09Å; P193-E196 HydrophobicContact CB-CG 4.04Å; P193-E196 PolarHBondContact O-N 3.04Å; E196-R198 VanDerWaalsContact C-N 3.32Å; E196-R198 PolarHBondContact O-N 2.98Å; E196-H199 PolarHBondContact O-N 2.79Å; E196-Y200 PolarHBondContact O-N 3.16Å; E196-Y200 VanDerWaalsContact O-N 3.1Å
197I94.7Very high87.3Confident0 Ų051.9 Ų51.90%026%0.26CS..Hα-helixtrans-60.9-44.9174.4-62.3162.2000109.4L179 W183 Q192 P193 L194 Y200 Y201 A206 F209L179-I197 HydrophobicContact CD1-CG1 4.1Å; W183-I197 HydrophobicContact CD2-CD1 4Å; W183-I197 HydrophobicContact CD2-CG1 3.97Å; W183-I197 HydrophobicContact CE3-CG1 4.22Å; W183-I197 HydrophobicContact CG-CD1 4.42Å; W183-I197 HydrophobicContact CH2-CD1 4.21Å; W183-I197 HydrophobicContact CH2-CG1 3.99Å; W183-I197 HydrophobicContact CH2-CG2 3.98Å; W183-I197 HydrophobicContact CZ2-CD1 3.43Å; W183-I197 VanDerWaalsContact CZ2-CD1 3.43Å; W183-I197 HydrophobicContact CZ2-CG1 3.72Å; W183-I197 HydrophobicContact CZ2-CG2 4.14Å; W183-I197 HydrophobicContact CZ3-CG1 4.25Å; Q192-I197 HydrophobicContact CB-CD1 4.47Å; P193-I197 HydrophobicContact CG-CD1 4.45Å; P193-I197 HydrophobicContact CG-CG1 4.49Å; P193-I197 WeakPolarHBondContact O-CG1 3.45Å; P193-I197 PolarHBondContact O-N 3.21Å; L194-I197 HydrophobicContact CD2-CD1 4.38Å; L194-I197 PolarHBondContact O-N 3.27Å; I197-Y200 PolarHBondContact O-N 3.1Å; I197-Y201 HydrophobicContact CG2-CD2 4.34Å; I197-Y201 WeakPolarHBondContact O-CB 3.38Å; I197-Y201 PolarHBondContact O-N 3.28Å; I197-A206 HydrophobicContact CG2-CB 4.24Å; I197-F209 HydrophobicContact CD1-CB 4.31Å; I197-F209 HydrophobicContact CG2-CD2 4.18Å
198R94.4Very high88.8Confident46 Ų4643.6 Ų43.617%0.17422%0.224CC..Hα-helixtrans-61.2-47176.7-178-129.6170174-4.2111.8L194 E196 Y200 G202 E203 A206 W269L194-R198 VanDerWaalsContact O-CB 3.24Å; L194-R198 WeakPolarHBondContact O-CB 3.45Å; L194-R198 PolarHBondContact O-N 3.07Å; E196-R198 VanDerWaalsContact C-N 3.32Å; E196-R198 PolarHBondContact O-N 2.98Å; R198-Y200 PolarHBondContact O-N 2.79Å; R198-G202 WeakPolarHBondContact O-CA 3.33Å; R198-G202 PolarHBondContact O-N 3.47Å; R198-E203 HydrophobicContact CG-CG 3.92Å; R198-E203 IonicContact CZ-OE1 2.84Å; R198-E203 VanDerWaalsContact CZ-OE1 3.3Å; R198-E203 IonicContact NE-OE1 2.67Å; R198-E203 PolarHBondContact NE-OE1 3.04Å; R198-E203 IonicContact NH2-OE1 3.94Å; R198-E203 PolarHBondContact NH2-OE1 3.42Å; R198-A206 HydrophobicContact CB-CB 3.61Å; R198-A206 HydrophobicContact CG-CB 4.29Å; R198-W269 HydrophobicContact CB-CZ2 4.41Å; R198-W269 HydrophobicContact CG-CD2 4.04Å; R198-W269 HydrophobicContact CG-CE3 4.45Å; R198-W269 HydrophobicContact CG-CG 4.25Å; R198-W269 VanDerWaalsContact CZ-CB 3.48Å; R198-W269 VanDerWaalsContact NH1-CD1 3.34Å; R198-W269 PolarHBondContact NH2-O 2.95Å
199H92.8Very high90.4Very high90 Ų9037.1 Ų37.142%0.41720%0.195SC..Hα-helixtrans-60.3-34.4179.3-169.587.5000112.2S117 A119 D195 E196S117-H199 WeakPolarHBondContact CB-CE1 3.28Å; S117-H199 WeakPolarHBondContact CB-ND1 3.07Å; A119-H199 WeakPolarHBondContact CB-O 3.36Å; D195-H199 WeakPolarHBondContact O-CB 3.47Å; D195-H199 PolarHBondContact O-N 3.2Å; E196-H199 PolarHBondContact O-N 2.79Å
200Y94.6Very high91.9Very high5 Ų530.1 Ų30.12%0.0216%0.16CC..Hα-helixtrans-90.4-45.7-177.7-163.8-89.7000114.3H171 H172 E175 L176 L179 E196 I197 R198 R542H171-Y200 AromaticContact ND1-CE1 3.59Å; H171-Y200 AromaticContact ND1-CZ 3.66Å; H171-Y200 PolarHBondContact ND1-OH 3.29Å; H172-Y200 HydrophobicContact CB-CE2 4.3Å; H172-Y200 PolarHBondContact N-OH 3.25Å; H172-Y200 VanDerWaalsContact N-OH 3.12Å; H172-Y200 PolarHBondContact O-OH 2.78Å; E175-Y200 HydrophobicContact CB-CD2 3.97Å; E175-Y200 HydrophobicContact CB-CE2 3.79Å; L176-Y200 HydrophobicContact CB-CE2 4.23Å; L176-Y200 WeakPolarHBondContact CB-OH 3.25Å; L176-Y200 HydrophobicContact CD1-CD1 4.4Å; L176-Y200 HydrophobicContact CD1-CE1 3.75Å; L179-Y200 HydrophobicContact CD2-CD1 4.24Å; L179-Y200 HydrophobicContact CD2-CG 4.04Å; E196-Y200 PolarHBondContact O-N 3.16Å; E196-Y200 VanDerWaalsContact O-N 3.1Å; I197-Y200 PolarHBondContact O-N 3.1Å; R198-Y200 PolarHBondContact O-N 2.79Å; Y200-R542 VanDerWaalsContact O-CZ 3.3Å; Y200-R542 PolarHBondContact O-NE 3.14Å; Y200-R542 PolarHBondContact O-NH2 3.44Å
201Y94.6Very high93.3Very high1 Ų126.9 Ų26.90%0.00414%0.137CC..Hα-helixtrans-104.8-16.6-173.6-71.4-73.7000114.2L176 L179 W183 I197 Q205 M536 R542 P543 A545L176-Y201 WeakPolarHBondContact CD1-OH 3.4Å; L179-Y201 HydrophobicContact CD2-CD2 4.19Å; L179-Y201 HydrophobicContact CD2-CE2 3.8Å; W183-Y201 HydrophobicContact CH2-CD2 4.47Å; W183-Y201 HydrophobicContact CH2-CE2 4.35Å; W183-Y201 HydrophobicContact CZ3-CD2 4.27Å; W183-Y201 AromaticContact CZ3-CE2 3.79Å; W183-Y201 HydrophobicContact CZ3-CE2 3.79Å; I197-Y201 HydrophobicContact CG2-CD2 4.34Å; I197-Y201 WeakPolarHBondContact O-CB 3.38Å; I197-Y201 PolarHBondContact O-N 3.28Å; Y201-Q205 PolarHBondContact O-OE1 3.49Å; Y201-M536 HydrophobicContact CD1-CE 3.82Å; Y201-M536 HydrophobicContact CE1-CB 4.47Å; Y201-M536 HydrophobicContact CE1-CE 3.95Å; Y201-M536 HydrophobicContact CG-CE 4.29Å; Y201-M536 PolarHBondContact OH-O 3.42Å; Y201-R542 HydrophobicContact CE1-CG 4.49Å; Y201-P543 HydrophobicContact CD1-CG 3.98Å; Y201-A545 WeakPolarHBondContact O-CA 3.44Å
202G93.6Very high93.9Very high1 Ų120.8 Ų20.81%0.0111%0.105CC..  trans100171.9-175.500000114.1R198 A206R198-G202 WeakPolarHBondContact O-CA 3.33Å; R198-G202 PolarHBondContact O-N 3.47Å; G202-A206 WeakPolarHBondContact O-CB 3.46Å; G202-A206 PolarHBondContact O-N 2.99Å
203E93.1Very high94.1Very high16 Ų1621.1 Ų21.18%0.07511%0.106CC..Hα-helixtrans-68.9-36.8-173.8-68.179.2-17100113.7R198 Q205 A206 L207 W269 T271R198-E203 HydrophobicContact CG-CG 3.92Å; R198-E203 IonicContact CZ-OE1 2.84Å; R198-E203 VanDerWaalsContact CZ-OE1 3.3Å; R198-E203 IonicContact NE-OE1 2.67Å; R198-E203 PolarHBondContact NE-OE1 3.04Å; R198-E203 IonicContact NH2-OE1 3.94Å; R198-E203 PolarHBondContact NH2-OE1 3.42Å; E203-Q205 PolarHBondContact O-N 3.14Å; E203-A206 PolarHBondContact O-N 2.95Å; E203-L207 WeakPolarHBondContact O-CB 3.33Å; E203-L207 WeakPolarHBondContact O-CG 3.35Å; E203-L207 PolarHBondContact O-N 3.21Å; E203-W269 HydrophobicContact CB-CE3 3.97Å; E203-W269 HydrophobicContact CB-CZ3 4.43Å; E203-W269 HydrophobicContact CG-CB 3.91Å; E203-W269 HydrophobicContact CG-CD2 4.23Å; E203-W269 HydrophobicContact CG-CE3 3.8Å; E203-W269 HydrophobicContact CG-CG 4.32Å; E203-T271 HydrophobicContact CB-CG2 4.12Å; E203-T271 HydrophobicContact CG-CG2 3.64Å
204G91.6Very high94.3Very high12 Ų1222 Ų2212%0.12411%0.107CC..Hα-helixtrans-59.9-45.2-179.500000113.2Y208 D546G204-Y208 PolarHBondContact O-N 2.83Å; G204-D546 PolarHBondContact N-O 3.27Å
205Q93.6Very high94.3Very high9 Ų921 Ų214%0.04210%0.101CC..Hα-helixtrans-70.9-42177.7-66.975.55.600110.7Y201 E203 L207 Y208 F209 M536 P543Y201-Q205 PolarHBondContact O-OE1 3.49Å; E203-Q205 PolarHBondContact O-N 3.14Å; Q205-L207 VanDerWaalsContact C-N 3.32Å; Q205-L207 PolarHBondContact O-N 3.14Å; Q205-Y208 WeakPolarHBondContact O-CB 3.39Å; Q205-Y208 PolarHBondContact O-N 3.44Å; Q205-Y208 VanDerWaalsContact O-N 3.17Å; Q205-F209 WeakPolarHBondContact O-CD2 3.37Å; Q205-F209 PolarHBondContact O-N 3.35Å; Q205-F209 VanDerWaalsContact O-N 3.13Å; Q205-M536 HydrophobicContact CG-CE 4.07Å; Q205-P543 HydrophobicContact CG-CG 4.36Å
206A95.3Very high94.4Very high0 Ų017.6 Ų17.60%08%0.083CC..Hα-helixtrans-63.6-35.8175.900000112.9I197 R198 G202 E203 Y208 G210 W269I197-A206 HydrophobicContact CG2-CB 4.24Å; R198-A206 HydrophobicContact CB-CB 3.61Å; R198-A206 HydrophobicContact CG-CB 4.29Å; G202-A206 WeakPolarHBondContact O-CB 3.46Å; G202-A206 PolarHBondContact O-N 2.99Å; E203-A206 PolarHBondContact O-N 2.95Å; A206-Y208 VanDerWaalsContact C-N 3.34Å; A206-G210 PolarHBondContact O-N 3.45Å; A206-W269 HydrophobicContact CB-CH2 3.58Å; A206-W269 HydrophobicContact CB-CZ2 4.16Å; A206-W269 HydrophobicContact CB-CZ3 3.99Å
207L95.4Very high94.4Very high1 Ų117.6 Ų17.61%0.0058%0.082CC..Hα-helixtrans-62.8-39.8172.6-82.3-175.5000112E203 Q205 G210 F211 W269 A548E203-L207 WeakPolarHBondContact O-CB 3.33Å; E203-L207 WeakPolarHBondContact O-CG 3.35Å; E203-L207 PolarHBondContact O-N 3.21Å; Q205-L207 VanDerWaalsContact C-N 3.32Å; Q205-L207 PolarHBondContact O-N 3.14Å; L207-G210 PolarHBondContact O-N 3.44Å; L207-F211 WeakPolarHBondContact O-CB 3.44Å; L207-F211 PolarHBondContact O-N 3.2Å; L207-W269 HydrophobicContact CD2-CE3 4.47Å; L207-W269 HydrophobicContact CD2-CH2 4.29Å; L207-W269 HydrophobicContact CD2-CZ3 3.65Å; L207-W269 HydrophobicContact CG-CZ3 3.75Å; L207-A548 HydrophobicContact CD1-CB 3.71Å
208Y95.6Very high94.4Very high2 Ų217.9 Ų17.91%0.0089%0.085CC..Hα-helixtrans-60.9-53.8176.2166.1-102.9000111.4G204 Q205 A206 G210 F211 L212 T493 D496 Y497 L500 D532G204-Y208 PolarHBondContact O-N 2.83Å; Q205-Y208 WeakPolarHBondContact O-CB 3.39Å; Q205-Y208 PolarHBondContact O-N 3.44Å; Q205-Y208 VanDerWaalsContact O-N 3.17Å; A206-Y208 VanDerWaalsContact C-N 3.34Å; Y208-G210 VanDerWaalsContact C-N 3.27Å; Y208-G210 PolarHBondContact O-N 3.29Å; Y208-F211 WeakPolarHBondContact O-CB 3.43Å; Y208-F211 PolarHBondContact O-N 2.98Å; Y208-L212 HydrophobicContact CE1-CD2 4.36Å; Y208-L212 PolarHBondContact O-N 3.2Å; Y208-T493 HydrophobicContact CG-CG2 4.19Å; Y208-D496 HydrophobicContact CD2-CB 4.11Å; Y208-D496 HydrophobicContact CE1-CB 4.12Å; Y208-D496 HydrophobicContact CE2-CB 3.41Å; Y208-D496 VanDerWaalsContact CE2-CB 3.41Å; Y208-D496 VanDerWaalsContact CZ-CB 3.43Å; Y208-Y497 WeakPolarHBondContact CA-OH 3.23Å; Y208-Y497 HydrophobicContact CD2-CD1 4.12Å; Y208-Y497 HydrophobicContact CD2-CD2 4.24Å; Y208-Y497 AromaticContact CD2-CE1 3.96Å; Y208-Y497 HydrophobicContact CD2-CE1 3.96Å; Y208-Y497 HydrophobicContact CD2-CE2 4.07Å; Y208-Y497 HydrophobicContact CD2-CG 4.24Å; Y208-Y497 AromaticContact CD2-CZ 3.93Å; Y208-Y497 PolarHBondContact N-OH 3.28Å; Y208-L500 HydrophobicContact CE2-CD1 3.94Å; Y208-D532 VanDerWaalsContact CE1-OD2 3.3Å; Y208-D532 WeakPolarHBondContact CE1-OD2 3.4Å; Y208-D532 VanDerWaalsContact CZ-OD2 3.29Å; Y208-D532 PolarHBondContact OH-OD2 2.85Å
209F95.1Very high94.5Very high2 Ų215.7 Ų15.71%0.0098%0.076CC..Hα-helixtrans-63.6-34.6178.4-77.5-76.2000112.7W183 Q192 L194 I197 Q205 L212 E213 D532 M536W183-F209 AromaticContact CH2-CD2 3.95Å; W183-F209 HydrophobicContact CH2-CD2 3.95Å; W183-F209 HydrophobicContact CH2-CE1 4.19Å; W183-F209 AromaticContact CH2-CE2 3.48Å; W183-F209 HydrophobicContact CH2-CE2 3.48Å; W183-F209 VanDerWaalsContact CH2-CE2 3.48Å; W183-F209 HydrophobicContact CH2-CG 4.5Å; W183-F209 AromaticContact CH2-CZ 3.6Å; W183-F209 HydrophobicContact CH2-CZ 3.6Å; W183-F209 AromaticContact CZ2-CD1 3.61Å; W183-F209 HydrophobicContact CZ2-CD1 3.61Å; W183-F209 AromaticContact CZ2-CD2 3.55Å; W183-F209 HydrophobicContact CZ2-CD2 3.55Å; W183-F209 AromaticContact CZ2-CE1 3.44Å; W183-F209 HydrophobicContact CZ2-CE1 3.44Å; W183-F209 VanDerWaalsContact CZ2-CE1 3.44Å; W183-F209 AromaticContact CZ2-CE2 3.4Å; W183-F209 HydrophobicContact CZ2-CE2 3.4Å; W183-F209 AromaticContact CZ2-CG 3.65Å; W183-F209 HydrophobicContact CZ2-CG 3.65Å; W183-F209 AromaticContact CZ2-CZ 3.33Å; W183-F209 HydrophobicContact CZ2-CZ 3.33Å; Q192-F209 PolarHBondContact NE2-O 2.91Å; L194-F209 HydrophobicContact CD2-CB 4.26Å; I197-F209 HydrophobicContact CD1-CB 4.31Å; I197-F209 HydrophobicContact CG2-CD2 4.18Å; Q205-F209 WeakPolarHBondContact O-CD2 3.37Å; Q205-F209 PolarHBondContact O-N 3.35Å; Q205-F209 VanDerWaalsContact O-N 3.13Å; F209-L212 HydrophobicContact CD1-CD2 4.37Å; F209-L212 PolarHBondContact O-N 2.98Å; F209-E213 WeakPolarHBondContact O-CB 3.45Å; F209-E213 PolarHBondContact O-N 2.99Å; F209-D532 HydrophobicContact CE1-CB 3.52Å; F209-D532 HydrophobicContact CZ-CB 3.67Å; F209-M536 HydrophobicContact CE2-CG 4.29Å; F209-M536 HydrophobicContact CZ-CG 4.17Å
210G95.3Very high94.5Very high4 Ų413.9 Ų13.94%0.0417%0.071CC..Hα-helixtrans-63.9-39.117200000112.7A206 L207 Y208 Y214A206-G210 PolarHBondContact O-N 3.45Å; L207-G210 PolarHBondContact O-N 3.44Å; Y208-G210 VanDerWaalsContact C-N 3.27Å; Y208-G210 PolarHBondContact O-N 3.29Å; G210-Y214 VanDerWaalsContact O-CB 3.23Å; G210-Y214 WeakPolarHBondContact O-CB 3.24Å; G210-Y214 PolarHBondContact O-N 3.46Å
211F96.6Very high94.5Very high1 Ų115.2 Ų15.20%0.0048%0.081CC..Hα-helixtrans-69.3-45.6175.2-177.3-113000111.3L207 Y208 E213 Y214 F215 W258 Y497 L500 I551 F558L207-F211 WeakPolarHBondContact O-CB 3.44Å; L207-F211 PolarHBondContact O-N 3.2Å; Y208-F211 WeakPolarHBondContact O-CB 3.43Å; Y208-F211 PolarHBondContact O-N 2.98Å; F211-E213 VanDerWaalsContact C-N 3.34Å; F211-E213 PolarHBondContact O-N 3.22Å; F211-Y214 PolarHBondContact O-N 3.36Å; F211-F215 HydrophobicContact CE1-CB 4.47Å; F211-F215 HydrophobicContact CZ-CB 4.43Å; F211-F215 HydrophobicContact CZ-CD2 4.27Å; F211-F215 HydrophobicContact CZ-CG 4.4Å; F211-F215 WeakPolarHBondContact O-CB 3.5Å; F211-F215 PolarHBondContact O-N 3.38Å; F211-W258 HydrophobicContact CB-CH2 3.64Å; F211-W258 HydrophobicContact CB-CZ2 3.54Å; F211-W258 HydrophobicContact CB-CZ3 4.26Å; F211-W258 AromaticContact CD2-CD1 3.85Å; F211-W258 AromaticContact CD2-CD2 3.55Å; F211-W258 HydrophobicContact CD2-CD2 3.55Å; F211-W258 AromaticContact CD2-CE2 3.37Å; F211-W258 HydrophobicContact CD2-CE3 4.05Å; F211-W258 AromaticContact CD2-CG 3.89Å; F211-W258 HydrophobicContact CD2-CG 3.89Å; F211-W258 HydrophobicContact CD2-CH2 4.25Å; F211-W258 AromaticContact CD2-CZ2 3.77Å; F211-W258 HydrophobicContact CD2-CZ2 3.77Å; F211-W258 HydrophobicContact CD2-CZ3 4.36Å; F211-W258 AromaticContact CD2-NE1 3.54Å; F211-W258 AromaticContact CE2-CD1 3.88Å; F211-W258 HydrophobicContact CE2-CD2 4.18Å; F211-W258 HydrophobicContact CE2-CG 4.02Å; F211-W258 AromaticContact CE2-NE1 3.96Å; F211-W258 HydrophobicContact CG-CH2 4.46Å; F211-W258 HydrophobicContact CG-CZ2 4.08Å; F211-W258 VanDerWaalsContact N-CH2 3.26Å; F211-Y497 HydrophobicContact CB-CE1 4.11Å; F211-Y497 AromaticContact CD1-CD1 3.9Å; F211-Y497 HydrophobicContact CD1-CD1 3.9Å; F211-Y497 AromaticContact CD1-CE1 3.61Å; F211-Y497 HydrophobicContact CD1-CE1 3.61Å; F211-Y497 HydrophobicContact CE1-CD1 4.29Å; F211-Y497 HydrophobicContact CE1-CE1 4.36Å; F211-Y497 HydrophobicContact CG-CE1 4.07Å; F211-L500 HydrophobicContact CD1-CD1 3.79Å; F211-L500 HydrophobicContact CE1-CB 4.42Å; F211-L500 HydrophobicContact CE1-CD1 4.02Å; F211-I551 HydrophobicContact CB-CG2 4.44Å; F211-I551 HydrophobicContact CD2-CD1 4.46Å; F211-I551 HydrophobicContact CE2-CD1 4.27Å; F211-I551 HydrophobicContact CZ-CD1 4.5Å; F211-F558 HydrophobicContact CE1-CD2 4.43Å; F211-F558 HydrophobicContact CE1-CE1 4.36Å; F211-F558 AromaticContact CE1-CE2 3.57Å; F211-F558 HydrophobicContact CE1-CE2 3.57Å; F211-F558 AromaticContact CE1-CZ 3.55Å; F211-F558 HydrophobicContact CE1-CZ 3.55Å; F211-F558 AromaticContact CZ-CD2 3.96Å; F211-F558 HydrophobicContact CZ-CD2 3.96Å; F211-F558 HydrophobicContact CZ-CE1 4.12Å; F211-F558 AromaticContact CZ-CE2 3.54Å; F211-F558 HydrophobicContact CZ-CE2 3.54Å; F211-F558 HydrophobicContact CZ-CG 4.48Å; F211-F558 AromaticContact CZ-CZ 3.65Å; F211-F558 HydrophobicContact CZ-CZ 3.65Å
212L95.1Very high94.4Very high0 Ų015.3 Ų15.30%08%0.081CC..Hα-helixtrans-56.9-47.1176.617663.5000111.3Y208 F209 T216 L500 N525 E528 V529Y208-L212 HydrophobicContact CE1-CD2 4.36Å; Y208-L212 PolarHBondContact O-N 3.2Å; F209-L212 HydrophobicContact CD1-CD2 4.37Å; F209-L212 PolarHBondContact O-N 2.98Å; L212-T216 WeakPolarHBondContact O-CB 3.34Å; L212-T216 PolarHBondContact O-N 3.15Å; L212-T216 PolarHBondContact O-OG1 3.41Å; L212-L500 HydrophobicContact CB-CD1 4.26Å; L212-L500 HydrophobicContact CD1-CD1 3.98Å; L212-L500 HydrophobicContact CD1-CD2 3.59Å; L212-L500 HydrophobicContact CD1-CG 4.37Å; L212-N525 HydrophobicContact CD1-CB 4.25Å; L212-E528 HydrophobicContact CD1-CB 4.5Å; L212-V529 HydrophobicContact CD2-CB 4.32Å; L212-V529 HydrophobicContact CD2-CG2 3.63Å; L212-V529 HydrophobicContact CG-CG2 3.71Å
213E93.7Very high94.4Very high25 Ų2515.7 Ų15.712%0.1179%0.085CC..Hα-helixtrans-58.2-55174.2179.2170.499.700111.7L191 Q192 F209 F211 F215 T216 F217L191-E213 WeakPolarHBondContact CA-OE2 3.48Å; L191-E213 WeakPolarHBondContact CD2-OE1 3.34Å; Q192-E213 VanDerWaalsContact CB-OE2 3.31Å; Q192-E213 WeakPolarHBondContact CB-OE2 3.49Å; Q192-E213 WeakPolarHBondContact CG-OE2 3.36Å; Q192-E213 PolarHBondContact N-OE2 3.3Å; F209-E213 WeakPolarHBondContact O-CB 3.45Å; F209-E213 PolarHBondContact O-N 2.99Å; F211-E213 VanDerWaalsContact C-N 3.34Å; F211-E213 PolarHBondContact O-N 3.22Å; E213-F215 VanDerWaalsContact C-N 3.29Å; E213-F215 PolarHBondContact O-N 2.89Å; E213-T216 WeakPolarHBondContact O-CB 3.29Å; E213-T216 PolarHBondContact O-N 3.06Å; E213-F217 HydrophobicContact CG-CD2 3.78Å; E213-F217 HydrophobicContact CG-CE2 3.55Å; E213-F217 VanDerWaalsContact O-CD2 3.23Å; E213-F217 WeakPolarHBondContact O-CD2 3.47Å; E213-F217 PolarHBondContact O-N 3.27Å; E213-F217 VanDerWaalsContact O-N 3.13Å
214Y95.3Very high94.3Very high46 Ų4620.5 Ų20.518%0.1811%0.11CC..Hα-helixtrans-55.7-47.7-178.6171.6-95.9000111.1G210 F211 F217 A218 I254 L257 W258G210-Y214 VanDerWaalsContact O-CB 3.23Å; G210-Y214 WeakPolarHBondContact O-CB 3.24Å; G210-Y214 PolarHBondContact O-N 3.46Å; F211-Y214 PolarHBondContact O-N 3.36Å; Y214-F217 PolarHBondContact O-N 3.22Å; Y214-A218 HydrophobicContact CE1-CB 4.12Å; Y214-A218 WeakPolarHBondContact O-CB 3.42Å; Y214-A218 PolarHBondContact O-N 3.18Å; Y214-I254 HydrophobicContact CE1-CB 4.38Å; Y214-I254 WeakPolarHBondContact CE1-O 2.91Å; Y214-I254 WeakPolarHBondContact OH-CA 3.16Å; Y214-I254 WeakPolarHBondContact OH-CB 3.2Å; Y214-I254 PolarHBondContact OH-O 3Å; Y214-L257 WeakPolarHBondContact OH-CB 3.42Å; Y214-W258 HydrophobicContact CD1-CB 3.98Å; Y214-W258 HydrophobicContact CD1-CD2 4.19Å; Y214-W258 AromaticContact CD1-CE3 3.66Å; Y214-W258 HydrophobicContact CD1-CE3 3.66Å; Y214-W258 HydrophobicContact CD1-CG 4.32Å; Y214-W258 HydrophobicContact CD2-CE3 4.27Å; Y214-W258 HydrophobicContact CE1-CB 3.64Å; Y214-W258 HydrophobicContact CE1-CE3 4.44Å; Y214-W258 HydrophobicContact CE1-CG 4.44Å; Y214-W258 AromaticContact CG-CE3 3.59Å; Y214-W258 HydrophobicContact CG-CE3 3.59Å; Y214-W258 HydrophobicContact CG-CZ3 4.16Å
215F95.3Very high94.2Very high2 Ų225 Ų251%0.00913%0.127CC..Hα-helixtrans-66.1-39.7-177-171.3-115.7000111.4F211 E213 F217 A218 L219 L500 F504F211-F215 HydrophobicContact CE1-CB 4.47Å; F211-F215 HydrophobicContact CZ-CB 4.43Å; F211-F215 HydrophobicContact CZ-CD2 4.27Å; F211-F215 HydrophobicContact CZ-CG 4.4Å; F211-F215 WeakPolarHBondContact O-CB 3.5Å; F211-F215 PolarHBondContact O-N 3.38Å; E213-F215 VanDerWaalsContact C-N 3.29Å; E213-F215 PolarHBondContact O-N 2.89Å; F215-F217 PolarHBondContact O-N 3.41Å; F215-A218 PolarHBondContact O-N 3.14Å; F215-L219 HydrophobicContact CD1-CD1 4.14Å; F215-L219 HydrophobicContact CE1-CD1 3.58Å; F215-L219 HydrophobicContact CE1-CG 4.26Å; F215-L219 HydrophobicContact CE2-CD1 4.37Å; F215-L219 HydrophobicContact CE2-CD2 4.2Å; F215-L219 HydrophobicContact CE2-CG 4.22Å; F215-L219 HydrophobicContact CZ-CD1 3.68Å; F215-L219 HydrophobicContact CZ-CD2 4.08Å; F215-L219 HydrophobicContact CZ-CG 4.01Å; F215-L219 WeakPolarHBondContact O-CG 3.41Å; F215-L219 PolarHBondContact O-N 3.42Å; F215-L500 HydrophobicContact CD1-CD2 4.3Å; F215-F504 HydrophobicContact CE1-CB 4.47Å; F215-F504 HydrophobicContact CE2-CB 4.23Å; F215-F504 AromaticContact CE2-CD2 3.65Å; F215-F504 HydrophobicContact CE2-CD2 3.65Å; F215-F504 HydrophobicContact CE2-CE2 4.38Å; F215-F504 HydrophobicContact CE2-CG 4.19Å; F215-F504 HydrophobicContact CZ-CB 3.6Å; F215-F504 AromaticContact CZ-CD2 3.68Å; F215-F504 HydrophobicContact CZ-CD2 3.68Å; F215-F504 HydrophobicContact CZ-CG 4.01Å
216T93.8Very high94Very high10 Ų1024.6 Ų24.66%0.06113%0.125CC..Hα-helixtrans-57.2-50.9173.3-55.20000111.3L212 E213 A218 L219 V220 N525 V526L212-T216 WeakPolarHBondContact O-CB 3.34Å; L212-T216 PolarHBondContact O-N 3.15Å; L212-T216 PolarHBondContact O-OG1 3.41Å; E213-T216 WeakPolarHBondContact O-CB 3.29Å; E213-T216 PolarHBondContact O-N 3.06Å; T216-A218 PolarHBondContact O-N 3.06Å; T216-L219 PolarHBondContact O-N 3.15Å; T216-V220 PolarHBondContact O-N 3.45Å; T216-N525 HydrophobicContact CG2-CB 4.01Å; T216-N525 WeakPolarHBondContact OG1-CB 3.49Å; T216-V526 HydrophobicContact CG2-CG2 3.95Å
217F93.8Very high93.7Very high96 Ų9627 Ų2742%0.42114%0.139SC..Hα-helixtrans-67.9-34.8178.1-70.4-59.5000112.8L191 E213 Y214 F215 L219 V220 P221L191-F217 HydrophobicContact CD2-CE2 4.14Å; E213-F217 HydrophobicContact CG-CD2 3.78Å; E213-F217 HydrophobicContact CG-CE2 3.55Å; E213-F217 VanDerWaalsContact O-CD2 3.23Å; E213-F217 WeakPolarHBondContact O-CD2 3.47Å; E213-F217 PolarHBondContact O-N 3.27Å; E213-F217 VanDerWaalsContact O-N 3.13Å; Y214-F217 PolarHBondContact O-N 3.22Å; F215-F217 PolarHBondContact O-N 3.41Å; F217-L219 VanDerWaalsContact C-N 3.28Å; F217-L219 PolarHBondContact O-N 3Å; F217-V220 PolarHBondContact O-N 2.98Å; F217-P221 WeakPolarHBondContact O-CD 3.45Å
218A95Very high93.4Very high7 Ų728.7 Ų28.76%0.05815%0.15CC..Hα-helixtrans-65.8-28.817800000112.9Y214 F215 T216 W250 I254Y214-A218 HydrophobicContact CE1-CB 4.12Å; Y214-A218 WeakPolarHBondContact O-CB 3.42Å; Y214-A218 PolarHBondContact O-N 3.18Å; F215-A218 PolarHBondContact O-N 3.14Å; T216-A218 PolarHBondContact O-N 3.06Å; A218-W250 PolarHBondContact O-NE1 2.92Å; A218-I254 HydrophobicContact CB-CB 4.04Å; A218-I254 HydrophobicContact CB-CD1 4.31Å; A218-I254 HydrophobicContact CB-CG2 3.78Å
219L94.6Very high92.9Very high0 Ų030 Ų300%016%0.156CC..Hα-helixtrans-82.3-18176.1-69.3-177.5000113.8F215 T216 F217 M222 A223 V507 V521 V522F215-L219 HydrophobicContact CD1-CD1 4.14Å; F215-L219 HydrophobicContact CE1-CD1 3.58Å; F215-L219 HydrophobicContact CE1-CG 4.26Å; F215-L219 HydrophobicContact CE2-CD1 4.37Å; F215-L219 HydrophobicContact CE2-CD2 4.2Å; F215-L219 HydrophobicContact CE2-CG 4.22Å; F215-L219 HydrophobicContact CZ-CD1 3.68Å; F215-L219 HydrophobicContact CZ-CD2 4.08Å; F215-L219 HydrophobicContact CZ-CG 4.01Å; F215-L219 WeakPolarHBondContact O-CG 3.41Å; F215-L219 PolarHBondContact O-N 3.42Å; T216-L219 PolarHBondContact O-N 3.15Å; F217-L219 VanDerWaalsContact C-N 3.28Å; F217-L219 PolarHBondContact O-N 3Å; L219-M222 HydrophobicContact CD2-CE 3.54Å; L219-M222 HydrophobicContact CD2-SD 3.84Å; L219-M222 WeakPolarHBondContact O-CB 3.23Å; L219-M222 PolarHBondContact O-N 3.26Å; L219-A223 PolarHBondContact O-N 3.28Å; L219-V507 HydrophobicContact CD2-CG1 4.29Å; L219-V521 HydrophobicContact CD1-CB 4.15Å; L219-V521 HydrophobicContact CD1-CG1 3.36Å; L219-V522 HydrophobicContact CB-CG2 3.57Å
220V94.2Very high92.3Very high51 Ų5136.3 Ų36.331%0.30918%0.18SC..Hα-helixtrans-56.4-46-179.9171.40000112.2T216 F217 M222 A223 L224 V522T216-V220 PolarHBondContact O-N 3.45Å; F217-V220 PolarHBondContact O-N 2.98Å; V220-M222 VanDerWaalsContact C-N 3.34Å; V220-M222 PolarHBondContact O-N 2.99Å; V220-A223 WeakPolarHBondContact O-CB 3.36Å; V220-A223 PolarHBondContact O-N 3.37Å; V220-L224 HydrophobicContact CG1-CD1 3.9Å; V220-L224 HydrophobicContact CG1-CG 4.15Å; V220-L224 WeakPolarHBondContact O-CG 3.46Å; V220-L224 PolarHBondContact O-N 3.42Å; V220-V522 HydrophobicContact CG2-CG1 4.14Å; V220-V522 HydrophobicContact CG2-CG2 4.38Å
221P94.3Very high91.9Very high34 Ų3442.6 Ų42.622%0.22121%0.21CC..Hα-helixtrans-58.5-41.8174.2-30.640.9000113.2F217 A223 L224 F225 F246 W250F217-P221 WeakPolarHBondContact O-CD 3.45Å; P221-A223 VanDerWaalsContact C-N 3.32Å; P221-A223 PolarHBondContact O-N 2.95Å; P221-L224 PolarHBondContact O-N 3.37Å; P221-F225 VanDerWaalsContact O-CD2 3.3Å; P221-F225 WeakPolarHBondContact O-CD2 3.31Å; P221-F225 PolarHBondContact O-N 2.69Å; P221-F246 HydrophobicContact CB-CZ 4.36Å; P221-W250 HydrophobicContact CB-CH2 4.48Å; P221-W250 HydrophobicContact CB-CZ2 3.87Å; P221-W250 HydrophobicContact CG-CH2 4.12Å; P221-W250 HydrophobicContact CG-CZ2 3.53Å
222M92.4Very high91.4Very high2 Ų248.8 Ų48.81%0.0124%0.237CC..Hα-helixtrans-61.3-42175.7-60.2-170.7-143.700111.8L219 V220 F225 G226 F246 W250 I254 V507 A518L219-M222 HydrophobicContact CD2-CE 3.54Å; L219-M222 HydrophobicContact CD2-SD 3.84Å; L219-M222 WeakPolarHBondContact O-CB 3.23Å; L219-M222 PolarHBondContact O-N 3.26Å; V220-M222 VanDerWaalsContact C-N 3.34Å; V220-M222 PolarHBondContact O-N 2.99Å; M222-F225 PolarHBondContact O-N 2.77Å; M222-G226 PolarHBondContact O-N 3.14Å; M222-F246 HydrophobicContact CG-CE1 4.38Å; M222-W250 VanDerWaalsContact CE-CD1 3.46Å; M222-W250 VanDerWaalsContact CG-CD1 3.45Å; M222-I254 HydrophobicContact CE-CD1 3.7Å; M222-V507 HydrophobicContact SD-CG1 3.7Å; M222-A518 HydrophobicContact CB-CB 3.86Å
223A92.6Very high90.6Very high10 Ų1054 Ų548%0.08327%0.265CS..Hα-helixtrans-63.2-43.7176.300000112L219 V220 P221 G226 V227 A518 V519 V522L219-A223 PolarHBondContact O-N 3.28Å; V220-A223 WeakPolarHBondContact O-CB 3.36Å; V220-A223 PolarHBondContact O-N 3.37Å; P221-A223 VanDerWaalsContact C-N 3.32Å; P221-A223 PolarHBondContact O-N 2.95Å; A223-G226 PolarHBondContact O-N 3.44Å; A223-V227 WeakPolarHBondContact O-CG2 3.43Å; A223-V227 PolarHBondContact O-N 2.95Å; A223-V227 VanDerWaalsContact O-N 3.1Å; A223-A518 HydrophobicContact CB-CB 4.07Å; A223-V519 HydrophobicContact CB-CG2 3.9Å; A223-V522 HydrophobicContact CB-CG2 4.26Å
224L92.3Very high89.9Confident117 Ų11757.5 Ų57.561%0.61328%0.277SS*.Hα-helixtrans-65.6-38.4178.8-70.4175.9000112.6V220 P221 P228V220-L224 HydrophobicContact CG1-CD1 3.9Å; V220-L224 HydrophobicContact CG1-CG 4.15Å; V220-L224 WeakPolarHBondContact O-CG 3.46Å; V220-L224 PolarHBondContact O-N 3.42Å; P221-L224 PolarHBondContact O-N 3.37Å; L224-P228 WeakPolarHBondContact O-CD 3.36Å
225F89.5Confident88.7Confident107 Ų10759.7 Ų59.747%0.46929%0.289SS..Hα-helixtrans-72.8-34.6173.5-85.2-89.1000111.9P221 M222 P228 Y229 F243 F246P221-F225 VanDerWaalsContact O-CD2 3.3Å; P221-F225 WeakPolarHBondContact O-CD2 3.31Å; P221-F225 PolarHBondContact O-N 2.69Å; M222-F225 PolarHBondContact O-N 2.77Å; F225-P228 WeakPolarHBondContact O-CD 3.11Å; F225-Y229 WeakPolarHBondContact O-CD2 3.13Å; F225-F243 HydrophobicContact CB-CE2 4.21Å; F225-F246 HydrophobicContact CB-CD1 4.41Å; F225-F246 HydrophobicContact CB-CE1 4Å; F225-F246 HydrophobicContact CB-CZ 4.47Å; F225-F246 AromaticContact CD2-CE1 3.93Å; F225-F246 HydrophobicContact CD2-CE1 3.93Å; F225-F246 AromaticContact CD2-CE2 3.95Å; F225-F246 HydrophobicContact CD2-CE2 3.95Å; F225-F246 AromaticContact CD2-CZ 3.53Å; F225-F246 HydrophobicContact CD2-CZ 3.53Å; F225-F246 AromaticContact CE2-CE2 3.88Å; F225-F246 HydrophobicContact CE2-CE2 3.88Å; F225-F246 AromaticContact CE2-CZ 3.92Å; F225-F246 HydrophobicContact CE2-CZ 3.92Å; F225-F246 HydrophobicContact CG-CD1 4.4Å; F225-F246 HydrophobicContact CG-CE1 4.01Å; F225-F246 HydrophobicContact CG-CZ 4.06Å; F225-F246 HydrophobicContact CZ-CE2 4.38Å
226G88Confident87.8Confident0 Ų064 Ų640%031%0.312CS..Hα-helixtrans-70.8-31-179.400000114.9M222 A223 Y229 Y230M222-G226 PolarHBondContact O-N 3.14Å; A223-G226 PolarHBondContact O-N 3.44Å; G226-Y229 WeakPolarHBondContact O-CB 2.79Å; G226-Y229 PolarHBondContact O-N 3.32Å; G226-Y230 PolarHBondContact O-N 2.91Å; G226-Y230 VanDerWaalsContact O-N 3.16Å
227V90.4Very high86.7Confident49 Ų4966.3 Ų66.330%0.29732%0.32SS..Hα-helixtrans-62.3-52-177.8166.60000113.1A223 Y229 Y230 M231 L516 V519A223-V227 WeakPolarHBondContact O-CG2 3.43Å; A223-V227 PolarHBondContact O-N 2.95Å; A223-V227 VanDerWaalsContact O-N 3.1Å; V227-Y229 PolarHBondContact O-N 3.44Å; V227-Y230 PolarHBondContact O-N 3.22Å; V227-M231 HydrophobicContact CG1-CG 4.11Å; V227-M231 HydrophobicContact CG1-SD 3.6Å; V227-M231 VanDerWaalsContact CG1-SD 3.6Å; V227-M231 WeakPolarHBondContact O-CB 3.02Å; V227-M231 WeakPolarHBondContact O-CG 3.34Å; V227-M231 PolarHBondContact O-N 3.45Å; V227-L516 HydrophobicContact CG2-CD2 4.26Å; V227-V519 HydrophobicContact CG2-CG2 3.56Å
228P88.6Confident85.9Confident38 Ų3867.2 Ų67.225%0.24733%0.329CS..Hα-helixtrans-59-36.6175.6-25.534.4000112.8L224 F225 Y230 M231 F232 W234L224-P228 WeakPolarHBondContact O-CD 3.36Å; F225-P228 WeakPolarHBondContact O-CD 3.11Å; P228-Y230 VanDerWaalsContact C-N 3.3Å; P228-Y230 PolarHBondContact O-N 3.18Å; P228-M231 PolarHBondContact O-N 3.06Å; P228-F232 HydrophobicContact CB-CD2 3.97Å; P228-F232 HydrophobicContact CB-CE2 4.18Å; P228-F232 WeakPolarHBondContact O-CB 3.3Å; P228-F232 VanDerWaalsContact O-CD2 3.31Å; P228-F232 WeakPolarHBondContact O-CD2 3.39Å; P228-F232 PolarHBondContact O-N 2.85Å; P228-W234 HydrophobicContact CB-CE3 4.33Å; P228-W234 HydrophobicContact CB-CH2 4.13Å; P228-W234 HydrophobicContact CB-CZ3 3.86Å
229Y85.1Confident85.3Confident30 Ų3069.8 Ų69.812%0.11834%0.339CS..Hα-helixtrans-60.9-41.8179.9-89.3-104.3000112.1F225 G226 V227 D233 W234 K239 F243F225-Y229 WeakPolarHBondContact O-CD2 3.13Å; G226-Y229 WeakPolarHBondContact O-CB 2.79Å; G226-Y229 PolarHBondContact O-N 3.32Å; V227-Y229 PolarHBondContact O-N 3.44Å; Y229-D233 PolarHBondContact O-N 2.79Å; Y229-W234 HydrophobicContact CD1-CB 4.09Å; Y229-W234 AromaticContact CD2-CE3 3.82Å; Y229-W234 HydrophobicContact CD2-CE3 3.82Å; Y229-W234 HydrophobicContact CD2-CZ3 4.33Å; Y229-W234 AromaticContact CE2-CE3 3.88Å; Y229-W234 HydrophobicContact CE2-CE3 3.88Å; Y229-W234 HydrophobicContact CE2-CZ3 4.24Å; Y229-W234 HydrophobicContact CG-CB 4.38Å; Y229-W234 HydrophobicContact CG-CE3 4.27Å; Y229-W234 PolarHBondContact O-N 3.13Å; Y229-W234 VanDerWaalsContact O-N 3.09Å; Y229-K239 HydrophobicContact CE1-CB 3.65Å; Y229-K239 VanDerWaalsContact CE1-O 3.24Å; Y229-K239 WeakPolarHBondContact CE1-O 3.48Å; Y229-K239 PolarHBondContact OH-O 3.08Å; Y229-F243 HydrophobicContact CD1-CB 4.27Å; Y229-F243 HydrophobicContact CD1-CG 4.45Å; Y229-F243 HydrophobicContact CD2-CD2 4.44Å; Y229-F243 HydrophobicContact CE1-CB 3.67Å; Y229-F243 HydrophobicContact CE1-CG 4.28Å; Y229-F243 HydrophobicContact CE2-CB 4.46Å; Y229-F243 HydrophobicContact CE2-CD2 4.3Å
230Y83.5Confident84.4Confident134 Ų13472 Ų7253%0.52535%0.348SS..Hα-helixtrans-76.8-42.7176.2-175-90.3000113G226 V227 P228 L516G226-Y230 PolarHBondContact O-N 2.91Å; G226-Y230 VanDerWaalsContact O-N 3.16Å; V227-Y230 PolarHBondContact O-N 3.22Å; P228-Y230 VanDerWaalsContact C-N 3.3Å; P228-Y230 PolarHBondContact O-N 3.18Å; Y230-L516 HydrophobicContact CD1-CD1 3.39Å; Y230-L516 HydrophobicContact CD1-CD2 4.23Å; Y230-L516 HydrophobicContact CD1-CG 3.88Å; Y230-L516 HydrophobicContact CD2-CD1 3.63Å; Y230-L516 HydrophobicContact CD2-CG 3.72Å; Y230-L516 HydrophobicContact CE1-CD1 3.47Å; Y230-L516 VanDerWaalsContact CE1-CD1 3.47Å; Y230-L516 HydrophobicContact CE1-CG 4.42Å; Y230-L516 HydrophobicContact CE2-CD1 3.7Å; Y230-L516 HydrophobicContact CE2-CG 4.27Å; Y230-L516 HydrophobicContact CG-CD1 3.45Å; Y230-L516 VanDerWaalsContact CG-CD1 3.45Å; Y230-L516 HydrophobicContact CG-CD2 4.04Å; Y230-L516 HydrophobicContact CG-CG 3.48Å; Y230-L516 VanDerWaalsContact CG-CG 3.48Å
231M86.3Confident83.8Confident135 Ų13571.8 Ų71.867%0.66535%0.347SS*.Hα-helixtrans-69.9-34.3-174.7-74.6-172.968.700113.8V227 P228V227-M231 HydrophobicContact CG1-CG 4.11Å; V227-M231 HydrophobicContact CG1-SD 3.6Å; V227-M231 VanDerWaalsContact CG1-SD 3.6Å; V227-M231 WeakPolarHBondContact O-CB 3.02Å; V227-M231 WeakPolarHBondContact O-CG 3.34Å; V227-M231 PolarHBondContact O-N 3.45Å; P228-M231 PolarHBondContact O-N 3.06Å
232F86.1Confident83.4Confident132 Ų13272.6 Ų72.658%0.57936%0.357SS*.THydrogen-bonded Turntrans-102.68.1-177.4-60.9-62.6000113.4P228 W234P228-F232 HydrophobicContact CB-CD2 3.97Å; P228-F232 HydrophobicContact CB-CE2 4.18Å; P228-F232 WeakPolarHBondContact O-CB 3.3Å; P228-F232 VanDerWaalsContact O-CD2 3.31Å; P228-F232 WeakPolarHBondContact O-CD2 3.39Å; P228-F232 PolarHBondContact O-N 2.85Å; F232-W234 VanDerWaalsContact C-N 3.27Å; F232-W234 VanDerWaalsContact CB-CD1 3.49Å; F232-W234 HydrophobicContact CB-CD2 4.32Å; F232-W234 HydrophobicContact CB-CG 4.12Å; F232-W234 VanDerWaalsContact CB-NE1 3.32Å; F232-W234 HydrophobicContact CD2-CZ2 4.02Å; F232-W234 PolarHBondContact O-N 3.4Å
233D77.4Confident83Confident110 Ų11072.8 Ų72.859%0.58836%0.357SS*.THydrogen-bonded Turntrans50.349.9-179.9-153.630.1000111.6Y229 E235Y229-D233 PolarHBondContact O-N 2.79Å; D233-E235 PolarHBondContact O-N 2.95Å; D233-E235 WeakPolarHBondContact OD1-CG 3.46Å
234W80Confident82.6Confident97 Ų9772.5 Ų72.537%0.36736%0.355SS..  trans-77.559.2-176.6-82.73000110.9P228 Y229 F232 D236 K239P228-W234 HydrophobicContact CB-CE3 4.33Å; P228-W234 HydrophobicContact CB-CH2 4.13Å; P228-W234 HydrophobicContact CB-CZ3 3.86Å; Y229-W234 HydrophobicContact CD1-CB 4.09Å; Y229-W234 AromaticContact CD2-CE3 3.82Å; Y229-W234 HydrophobicContact CD2-CE3 3.82Å; Y229-W234 HydrophobicContact CD2-CZ3 4.33Å; Y229-W234 AromaticContact CE2-CE3 3.88Å; Y229-W234 HydrophobicContact CE2-CE3 3.88Å; Y229-W234 HydrophobicContact CE2-CZ3 4.24Å; Y229-W234 HydrophobicContact CG-CB 4.38Å; Y229-W234 HydrophobicContact CG-CE3 4.27Å; Y229-W234 PolarHBondContact O-N 3.13Å; Y229-W234 VanDerWaalsContact O-N 3.09Å; F232-W234 VanDerWaalsContact C-N 3.27Å; F232-W234 VanDerWaalsContact CB-CD1 3.49Å; F232-W234 HydrophobicContact CB-CD2 4.32Å; F232-W234 HydrophobicContact CB-CG 4.12Å; F232-W234 VanDerWaalsContact CB-NE1 3.32Å; F232-W234 HydrophobicContact CD2-CZ2 4.02Å; F232-W234 PolarHBondContact O-N 3.4Å; W234-D236 VanDerWaalsContact C-N 3.27Å; W234-D236 PolarHBondContact O-N 3.37Å; W234-K239 HydrophobicContact CB-CB 4.44Å; W234-K239 HydrophobicContact CB-CD 3.41Å; W234-K239 VanDerWaalsContact CB-CD 3.41Å; W234-K239 HydrophobicContact CD2-CD 3.89Å; W234-K239 HydrophobicContact CE3-CD 4.34Å; W234-K239 HydrophobicContact CG-CD 3.46Å; W234-K239 VanDerWaalsContact CG-CD 3.46Å
235E69.5Low82.3Confident92 Ų9269.7 Ų69.743%0.4334%0.342SS..  trans-853.8-178.1-56.5-162.3148.300113D233 Y237 Y240 Q578D233-E235 PolarHBondContact O-N 2.95Å; D233-E235 WeakPolarHBondContact OD1-CG 3.46Å; E235-Y237 PolarHBondContact O-N 3.43Å; E235-Y240 VanDerWaalsContact CA-CE2 3.47Å; E235-Y240 HydrophobicContact CB-CE2 3.8Å; E235-Y240 HydrophobicContact CG-CE2 4.48Å; E235-Y240 WeakPolarHBondContact CG-OH 3.35Å; E235-Y240 VanDerWaalsContact O-CD2 3.28Å; E235-Y240 WeakPolarHBondContact O-CD2 3.46Å; E235-Y240 WeakPolarHBondContact O-CE2 3.3Å; E235-Q578 VanDerWaalsContact O-CD 3.29Å; E235-Q578 PolarHBondContact O-NE2 3.44Å; E235-Q578 PolarHBondContact O-OE1 3.49Å; E235-Q578 VanDerWaalsContact O-OE1 3.06Å
236D75.9Confident82.4Confident93 Ų9366.8 Ų66.850%0.49733%0.33SS..  trans-61.7140.8176.2-67.1-48.5000111W234 D238 K239 Y240W234-D236 VanDerWaalsContact C-N 3.27Å; W234-D236 PolarHBondContact O-N 3.37Å; D236-D238 VanDerWaalsContact C-N 3.28Å; D236-D238 PolarHBondContact O-N 2.92Å; D236-D238 VanDerWaalsContact O-N 3.16Å; D236-K239 HydrophobicContact CB-CD 4.28Å; D236-K239 HydrophobicContact CB-CG 4.16Å; D236-K239 WeakPolarHBondContact O-CA 3.4Å; D236-K239 WeakPolarHBondContact O-CB 3.31Å; D236-K239 PolarHBondContact O-N 3.41Å; D236-K239 IonicContact OD2-NZ 3.77Å; D236-K239 PolarHBondContact OD2-NZ 2.98Å; D236-Y240 PolarHBondContact O-N 2.99Å; D236-Y240 VanDerWaalsContact O-N 3.09Å
237Y71.5Confident82.4Confident58 Ų5867.1 Ų67.123%0.22733%0.331CS..Hα-helixtrans-47.8-47.9-178.5170.4-114.1000113.5E235 K239 Y240 V241 I573 V579 Y582E235-Y237 PolarHBondContact O-N 3.43Å; Y237-K239 PolarHBondContact O-N 3.27Å; Y237-Y240 PolarHBondContact O-N 3.34Å; Y237-V241 HydrophobicContact CD2-CG2 3.88Å; Y237-V241 HydrophobicContact CE1-CG2 4.21Å; Y237-V241 HydrophobicContact CE2-CG2 3.27Å; Y237-V241 WeakPolarHBondContact O-CG2 3.22Å; Y237-V241 PolarHBondContact O-N 2.88Å; Y237-I573 HydrophobicContact CD2-CG2 4.45Å; Y237-I573 HydrophobicContact CE2-CG2 3.8Å; Y237-V579 HydrophobicContact CD2-CG2 3.18Å; Y237-V579 HydrophobicContact CE2-CB 4.4Å; Y237-V579 HydrophobicContact CE2-CG2 3.04Å; Y237-V579 HydrophobicContact CG-CG2 4.19Å; Y237-Y582 AromaticContact CD1-CE2 3.95Å; Y237-Y582 HydrophobicContact CD1-CE2 3.95Å; Y237-Y582 HydrophobicContact CE1-CE2 4.42Å; Y237-Y582 HydrophobicContact CG-CE2 4.36Å
238D76.9Confident82.2Confident115 Ų11565.1 Ų65.162%0.61532%0.319SS*.Hα-helixtrans-59.3-33.4-179.2-62.2-15.2000112D236 A242D236-D238 VanDerWaalsContact C-N 3.28Å; D236-D238 PolarHBondContact O-N 2.92Å; D236-D238 VanDerWaalsContact O-N 3.16Å; D238-A242 VanDerWaalsContact O-CB 3.31Å; D238-A242 WeakPolarHBondContact O-CB 3.43Å; D238-A242 PolarHBondContact O-N 3Å
239K81.4Confident82.3Confident61 Ų6164.9 Ų64.927%0.26532%0.317SS..Hα-helixtrans-76.1-43.5179.5-57-173-179.167.30110.2Y229 W234 D236 Y237 V241 A242 F243Y229-K239 HydrophobicContact CE1-CB 3.65Å; Y229-K239 VanDerWaalsContact CE1-O 3.24Å; Y229-K239 WeakPolarHBondContact CE1-O 3.48Å; Y229-K239 PolarHBondContact OH-O 3.08Å; W234-K239 HydrophobicContact CB-CB 4.44Å; W234-K239 HydrophobicContact CB-CD 3.41Å; W234-K239 VanDerWaalsContact CB-CD 3.41Å; W234-K239 HydrophobicContact CD2-CD 3.89Å; W234-K239 HydrophobicContact CE3-CD 4.34Å; W234-K239 HydrophobicContact CG-CD 3.46Å; W234-K239 VanDerWaalsContact CG-CD 3.46Å; D236-K239 HydrophobicContact CB-CD 4.28Å; D236-K239 HydrophobicContact CB-CG 4.16Å; D236-K239 WeakPolarHBondContact O-CA 3.4Å; D236-K239 WeakPolarHBondContact O-CB 3.31Å; D236-K239 PolarHBondContact O-N 3.41Å; D236-K239 IonicContact OD2-NZ 3.77Å; D236-K239 PolarHBondContact OD2-NZ 2.98Å; Y237-K239 PolarHBondContact O-N 3.27Å; K239-V241 VanDerWaalsContact C-N 3.34Å; K239-V241 PolarHBondContact O-N 3.41Å; K239-A242 PolarHBondContact O-N 2.85Å; K239-F243 PolarHBondContact O-N 2.83Å
240Y77Confident82.7Confident47 Ų4766.5 Ų66.518%0.18432%0.323CS..Hα-helixtrans-59.2-44.2174.7-81.7-53.9000112.9E235 D236 Y237 F243 A244 C512E235-Y240 VanDerWaalsContact CA-CE2 3.47Å; E235-Y240 HydrophobicContact CB-CE2 3.8Å; E235-Y240 HydrophobicContact CG-CE2 4.48Å; E235-Y240 WeakPolarHBondContact CG-OH 3.35Å; E235-Y240 VanDerWaalsContact O-CD2 3.28Å; E235-Y240 WeakPolarHBondContact O-CD2 3.46Å; E235-Y240 WeakPolarHBondContact O-CE2 3.3Å; D236-Y240 PolarHBondContact O-N 2.99Å; D236-Y240 VanDerWaalsContact O-N 3.09Å; Y237-Y240 PolarHBondContact O-N 3.34Å; Y240-F243 PolarHBondContact O-N 2.98Å; Y240-A244 WeakPolarHBondContact O-CB 3.32Å; Y240-A244 PolarHBondContact O-N 3.49Å; Y240-C512 HydrophobicContact CD1-CB 4.26Å; Y240-C512 WeakPolarHBondContact CE1-O 3.39Å
241V81.1Confident83.2Confident46 Ų4660.3 Ų60.328%0.27930%0.299SS..Hα-helixtrans-62.8-45.2176175.60000110.5Y237 K239 F243 A244 V245 I573Y237-V241 HydrophobicContact CD2-CG2 3.88Å; Y237-V241 HydrophobicContact CE1-CG2 4.21Å; Y237-V241 HydrophobicContact CE2-CG2 3.27Å; Y237-V241 WeakPolarHBondContact O-CG2 3.22Å; Y237-V241 PolarHBondContact O-N 2.88Å; K239-V241 VanDerWaalsContact C-N 3.34Å; K239-V241 PolarHBondContact O-N 3.41Å; V241-F243 VanDerWaalsContact C-N 3.33Å; V241-F243 PolarHBondContact O-N 2.79Å; V241-A244 PolarHBondContact O-N 2.86Å; V241-V245 HydrophobicContact CG1-CG2 4.27Å; V241-V245 WeakPolarHBondContact O-CB 3.03Å; V241-V245 VanDerWaalsContact O-CG2 3.27Å; V241-V245 WeakPolarHBondContact O-CG2 2.93Å; V241-V245 PolarHBondContact O-N 3.31Å; V241-I573 HydrophobicContact CG2-CG2 4.2Å
242A85.6Confident83.5Confident52 Ų5253.9 Ų53.943%0.4327%0.268SS..Hα-helixtrans-59.6-43.1177.700000112.2D238 K239 F246D238-A242 VanDerWaalsContact O-CB 3.31Å; D238-A242 WeakPolarHBondContact O-CB 3.43Å; D238-A242 PolarHBondContact O-N 3Å; K239-A242 PolarHBondContact O-N 2.85Å; A242-F246 WeakPolarHBondContact O-CB 3.42Å; A242-F246 PolarHBondContact O-N 3.18Å
243F85Confident83.9Confident5 Ų549.8 Ų49.82%0.02225%0.251CS..Hα-helixtrans-66.9-43.8177.7-172.2-118.8000112.5F225 Y229 K239 Y240 V241 F246 N247 S511 P515F225-F243 HydrophobicContact CB-CE2 4.21Å; Y229-F243 HydrophobicContact CD1-CB 4.27Å; Y229-F243 HydrophobicContact CD1-CG 4.45Å; Y229-F243 HydrophobicContact CD2-CD2 4.44Å; Y229-F243 HydrophobicContact CE1-CB 3.67Å; Y229-F243 HydrophobicContact CE1-CG 4.28Å; Y229-F243 HydrophobicContact CE2-CB 4.46Å; Y229-F243 HydrophobicContact CE2-CD2 4.3Å; K239-F243 PolarHBondContact O-N 2.83Å; Y240-F243 PolarHBondContact O-N 2.98Å; V241-F243 VanDerWaalsContact C-N 3.33Å; V241-F243 PolarHBondContact O-N 2.79Å; F243-F246 HydrophobicContact CD2-CD1 4.46Å; F243-F246 WeakPolarHBondContact O-CB 3.26Å; F243-F246 PolarHBondContact O-N 2.95Å; F243-N247 VanDerWaalsContact CD1-ND2 3.3Å; F243-N247 WeakPolarHBondContact CD1-ND2 3.44Å; F243-N247 WeakPolarHBondContact CE1-ND2 3.49Å; F243-N247 WeakPolarHBondContact CZ-ND2 3.23Å; F243-N247 WeakPolarHBondContact O-CB 2.83Å; F243-N247 PolarHBondContact O-N 3.32Å; F243-N247 PolarHBondContact O-ND2 3.43Å; F243-S511 VanDerWaalsContact CE1-O 3.32Å; F243-S511 WeakPolarHBondContact CE1-O 3.42Å; F243-P515 HydrophobicContact CE1-CB 4Å; F243-P515 HydrophobicContact CE1-CG 4.14Å; F243-P515 HydrophobicContact CZ-CB 4Å
244A83.1Confident84.8Confident5 Ų544.6 Ų44.64%0.04122%0.224CC..Hα-helixtrans-62.8-45177.800000112.3Y240 V241 N247 V248 N569 I573Y240-A244 WeakPolarHBondContact O-CB 3.32Å; Y240-A244 PolarHBondContact O-N 3.49Å; V241-A244 PolarHBondContact O-N 2.86Å; A244-N247 PolarHBondContact O-N 3.4Å; A244-V248 WeakPolarHBondContact O-CG2 3.46Å; A244-V248 PolarHBondContact O-N 2.71Å; A244-N569 HydrophobicContact CB-CB 4.44Å; A244-I573 HydrophobicContact CB-CD1 3.5Å; A244-I573 VanDerWaalsContact CB-CD1 3.5Å
245V86.4Confident85.6Confident57 Ų5740.2 Ų40.235%0.34521%0.207SC..Hα-helixtrans-61.5-46.8175.7172.70000110V241 N247 V248 V249 L601V241-V245 HydrophobicContact CG1-CG2 4.27Å; V241-V245 WeakPolarHBondContact O-CB 3.03Å; V241-V245 VanDerWaalsContact O-CG2 3.27Å; V241-V245 WeakPolarHBondContact O-CG2 2.93Å; V241-V245 PolarHBondContact O-N 3.31Å; V245-N247 VanDerWaalsContact C-N 3.35Å; V245-N247 PolarHBondContact O-N 3.45Å; V245-V248 PolarHBondContact O-N 3.2Å; V245-V249 HydrophobicContact CG1-CG2 4.36Å; V245-V249 WeakPolarHBondContact O-CB 3.04Å; V245-V249 VanDerWaalsContact O-CG2 3.26Å; V245-V249 WeakPolarHBondContact O-CG2 3.44Å; V245-V249 PolarHBondContact O-N 3.47Å; V245-L601 HydrophobicContact CG2-CD2 4.26Å
246F90.8Very high86.8Confident47 Ų4735.9 Ų35.921%0.20619%0.187CC..Hα-helixtrans-55.1-49.5174.8167.5-99000111.5P221 M222 F225 A242 F243 V248 V249 W250P221-F246 HydrophobicContact CB-CZ 4.36Å; M222-F246 HydrophobicContact CG-CE1 4.38Å; F225-F246 HydrophobicContact CB-CD1 4.41Å; F225-F246 HydrophobicContact CB-CE1 4Å; F225-F246 HydrophobicContact CB-CZ 4.47Å; F225-F246 AromaticContact CD2-CE1 3.93Å; F225-F246 HydrophobicContact CD2-CE1 3.93Å; F225-F246 AromaticContact CD2-CE2 3.95Å; F225-F246 HydrophobicContact CD2-CE2 3.95Å; F225-F246 AromaticContact CD2-CZ 3.53Å; F225-F246 HydrophobicContact CD2-CZ 3.53Å; F225-F246 AromaticContact CE2-CE2 3.88Å; F225-F246 HydrophobicContact CE2-CE2 3.88Å; F225-F246 AromaticContact CE2-CZ 3.92Å; F225-F246 HydrophobicContact CE2-CZ 3.92Å; F225-F246 HydrophobicContact CG-CD1 4.4Å; F225-F246 HydrophobicContact CG-CE1 4.01Å; F225-F246 HydrophobicContact CG-CZ 4.06Å; F225-F246 HydrophobicContact CZ-CE2 4.38Å; A242-F246 WeakPolarHBondContact O-CB 3.42Å; A242-F246 PolarHBondContact O-N 3.18Å; F243-F246 HydrophobicContact CD2-CD1 4.46Å; F243-F246 WeakPolarHBondContact O-CB 3.26Å; F243-F246 PolarHBondContact O-N 2.95Å; F246-V248 PolarHBondContact O-N 2.86Å; F246-V249 PolarHBondContact O-N 2.71Å; F246-W250 HydrophobicContact CE1-CB 4.49Å; F246-W250 HydrophobicContact CE2-CB 4.31Å; F246-W250 HydrophobicContact CE2-CG 4.42Å; F246-W250 HydrophobicContact CZ-CB 4.23Å; F246-W250 HydrophobicContact CZ-CD2 4.42Å; F246-W250 HydrophobicContact CZ-CG 4.1Å; F246-W250 WeakPolarHBondContact O-CB 3.49Å; F246-W250 PolarHBondContact O-N 3.11Å
247N88.6Confident87.8Confident6 Ų634.8 Ų34.83%0.03218%0.181CC..Hα-helixtrans-63.9-42.9-178.3-73.9-30.6000112.7F243 A244 V245 W250 C251 S511F243-N247 VanDerWaalsContact CD1-ND2 3.3Å; F243-N247 WeakPolarHBondContact CD1-ND2 3.44Å; F243-N247 WeakPolarHBondContact CE1-ND2 3.49Å; F243-N247 WeakPolarHBondContact CZ-ND2 3.23Å; F243-N247 WeakPolarHBondContact O-CB 2.83Å; F243-N247 PolarHBondContact O-N 3.32Å; F243-N247 PolarHBondContact O-ND2 3.43Å; A244-N247 PolarHBondContact O-N 3.4Å; V245-N247 VanDerWaalsContact C-N 3.35Å; V245-N247 PolarHBondContact O-N 3.45Å; N247-W250 PolarHBondContact O-N 2.67Å; N247-C251 WeakPolarHBondContact O-CB 3.24Å; N247-C251 PolarHBondContact O-N 3.25Å; N247-C251 PolarHBondContact O-SG 3.46Å; N247-S511 WeakPolarHBondContact ND2-CB 3.31Å; N247-S511 PolarHBondContact ND2-OG 2.88Å
248V85.4Confident89Confident7 Ų732.2 Ų32.24%0.04217%0.171CC..Hα-helixtrans-61.5-47177.6165.10000111.3A244 V245 F246 T252 V566A244-V248 WeakPolarHBondContact O-CG2 3.46Å; A244-V248 PolarHBondContact O-N 2.71Å; V245-V248 PolarHBondContact O-N 3.2Å; F246-V248 PolarHBondContact O-N 2.86Å; V248-T252 PolarHBondContact O-N 3.4Å; V248-T252 VanDerWaalsContact O-N 3.16Å; V248-T252 PolarHBondContact O-OG1 2.82Å; V248-V566 HydrophobicContact CB-CG2 4.34Å; V248-V566 HydrophobicContact CG1-CG2 3.64Å; V248-V566 HydrophobicContact CG2-CB 4.44Å; V248-V566 HydrophobicContact CG2-CG2 3.78Å
249V91Very high89.8Confident34 Ų3428.3 Ų28.321%0.20615%0.148CC..Hα-helixtrans-66.2-46.4179.8174.50000110.3V245 F246 T252 I253 F604 L608V245-V249 HydrophobicContact CG1-CG2 4.36Å; V245-V249 WeakPolarHBondContact O-CB 3.04Å; V245-V249 VanDerWaalsContact O-CG2 3.26Å; V245-V249 WeakPolarHBondContact O-CG2 3.44Å; V245-V249 PolarHBondContact O-N 3.47Å; F246-V249 PolarHBondContact O-N 2.71Å; V249-T252 WeakPolarHBondContact O-CB 3.4Å; V249-T252 PolarHBondContact O-N 3.33Å; V249-I253 HydrophobicContact CG1-CD1 3.71Å; V249-I253 HydrophobicContact CG1-CG1 4.42Å; V249-I253 WeakPolarHBondContact O-CG1 3.41Å; V249-I253 PolarHBondContact O-N 3.45Å; V249-F604 HydrophobicContact CG1-CE1 4.38Å; V249-F604 HydrophobicContact CG2-CD1 4.06Å; V249-F604 HydrophobicContact CG2-CE1 3.59Å; V249-L608 HydrophobicContact CG1-CD1 4.15Å
250W94.9Very high90.5Very high64 Ų6428.6 Ų28.624%0.24215%0.148CC..Hα-helixtrans-64.4-46-179.3-170.1-110.1000112A218 P221 M222 F246 N247 T252 I253 I254A218-W250 PolarHBondContact O-NE1 2.92Å; P221-W250 HydrophobicContact CB-CH2 4.48Å; P221-W250 HydrophobicContact CB-CZ2 3.87Å; P221-W250 HydrophobicContact CG-CH2 4.12Å; P221-W250 HydrophobicContact CG-CZ2 3.53Å; M222-W250 VanDerWaalsContact CE-CD1 3.46Å; M222-W250 VanDerWaalsContact CG-CD1 3.45Å; F246-W250 HydrophobicContact CE1-CB 4.49Å; F246-W250 HydrophobicContact CE2-CB 4.31Å; F246-W250 HydrophobicContact CE2-CG 4.42Å; F246-W250 HydrophobicContact CZ-CB 4.23Å; F246-W250 HydrophobicContact CZ-CD2 4.42Å; F246-W250 HydrophobicContact CZ-CG 4.1Å; F246-W250 WeakPolarHBondContact O-CB 3.49Å; F246-W250 PolarHBondContact O-N 3.11Å; N247-W250 PolarHBondContact O-N 2.67Å; W250-T252 PolarHBondContact O-N 3.45Å; W250-I253 PolarHBondContact O-N 3.49Å; W250-I253 VanDerWaalsContact O-N 3.15Å; W250-I254 HydrophobicContact CD2-CG2 4.18Å; W250-I254 HydrophobicContact CG-CG2 4.4Å; W250-I254 HydrophobicContact CZ2-CG2 3.95Å; W250-I254 WeakPolarHBondContact O-CG1 3.45Å; W250-I254 WeakPolarHBondContact O-CG2 3.33Å; W250-I254 PolarHBondContact O-N 2.77Å
251C93.2Very high91.4Very high3 Ų328.7 Ų28.72%0.0216%0.155CC..Hα-helixtrans-56.6-37.2174.2-73.10000112.3N247 I254 L255 F504N247-C251 WeakPolarHBondContact O-CB 3.24Å; N247-C251 PolarHBondContact O-N 3.25Å; N247-C251 PolarHBondContact O-SG 3.46Å; C251-I254 VanDerWaalsContact O-CG1 3.3Å; C251-I254 WeakPolarHBondContact O-CG1 3.23Å; C251-L255 VanDerWaalsContact O-CG 3.31Å; C251-L255 WeakPolarHBondContact O-CG 3.34Å; C251-L255 PolarHBondContact O-N 2.98Å; C251-F504 HydrophobicContact CB-CE2 4.44Å; C251-F504 HydrophobicContact CB-CZ 4.12Å
252T92.9Very high92.1Very high1 Ų126.8 Ų26.81%0.00614%0.144CC..Hα-helixtrans-68.9-49.1176.4-53.30000110.8V248 V249 W250 I254 L255 E256 K605 L608V248-T252 PolarHBondContact O-N 3.4Å; V248-T252 VanDerWaalsContact O-N 3.16Å; V248-T252 PolarHBondContact O-OG1 2.82Å; V249-T252 WeakPolarHBondContact O-CB 3.4Å; V249-T252 PolarHBondContact O-N 3.33Å; W250-T252 PolarHBondContact O-N 3.45Å; T252-I254 VanDerWaalsContact C-N 3.33Å; T252-I254 PolarHBondContact O-N 3.03Å; T252-L255 PolarHBondContact O-N 3.24Å; T252-E256 HydrophobicContact CG2-CG 4.5Å; T252-E256 WeakPolarHBondContact O-CG 3.47Å; T252-E256 PolarHBondContact O-N 2.91Å; T252-E256 VanDerWaalsContact O-N 3.14Å; T252-K605 HydrophobicContact CG2-CG 3.91Å; T252-K605 WeakPolarHBondContact OG1-CG 3Å; T252-K605 PolarHBondContact OG1-NZ 3.36Å; T252-L608 HydrophobicContact CG2-CB 4.08Å; T252-L608 HydrophobicContact CG2-CD1 4.48Å
253I95.1Very high92.5Very high45 Ų4524.6 Ų24.623%0.23113%0.126CC..Hα-helixtrans-58.6-44.2-179.8-69.7169.3000111.3V249 W250 L255 E256 L257V249-I253 HydrophobicContact CG1-CD1 3.71Å; V249-I253 HydrophobicContact CG1-CG1 4.42Å; V249-I253 WeakPolarHBondContact O-CG1 3.41Å; V249-I253 PolarHBondContact O-N 3.45Å; W250-I253 PolarHBondContact O-N 3.49Å; W250-I253 VanDerWaalsContact O-N 3.15Å; I253-L255 PolarHBondContact O-N 3.29Å; I253-E256 PolarHBondContact O-N 3.37Å; I253-L257 HydrophobicContact CG2-CD1 3.59Å; I253-L257 HydrophobicContact CG2-CG 4.02Å; I253-L257 WeakPolarHBondContact O-CB 3.2Å; I253-L257 VanDerWaalsContact O-CG 3.24Å; I253-L257 WeakPolarHBondContact O-CG 3.17Å; I253-L257 PolarHBondContact O-N 3.3Å
254I95.8Very high93Very high2 Ų227 Ų271%0.0114%0.141CC..Hα-helixtrans-66.4-37.4-176.766.7175.3000112.1Y214 A218 M222 W250 C251 T252 W258 F504Y214-I254 HydrophobicContact CE1-CB 4.38Å; Y214-I254 WeakPolarHBondContact CE1-O 2.91Å; Y214-I254 WeakPolarHBondContact OH-CA 3.16Å; Y214-I254 WeakPolarHBondContact OH-CB 3.2Å; Y214-I254 PolarHBondContact OH-O 3Å; A218-I254 HydrophobicContact CB-CB 4.04Å; A218-I254 HydrophobicContact CB-CD1 4.31Å; A218-I254 HydrophobicContact CB-CG2 3.78Å; M222-I254 HydrophobicContact CE-CD1 3.7Å; W250-I254 HydrophobicContact CD2-CG2 4.18Å; W250-I254 HydrophobicContact CG-CG2 4.4Å; W250-I254 HydrophobicContact CZ2-CG2 3.95Å; W250-I254 WeakPolarHBondContact O-CG1 3.45Å; W250-I254 WeakPolarHBondContact O-CG2 3.33Å; W250-I254 PolarHBondContact O-N 2.77Å; C251-I254 VanDerWaalsContact O-CG1 3.3Å; C251-I254 WeakPolarHBondContact O-CG1 3.23Å; T252-I254 VanDerWaalsContact C-N 3.33Å; T252-I254 PolarHBondContact O-N 3.03Å; I254-W258 WeakPolarHBondContact O-CB 3.29Å; I254-W258 PolarHBondContact O-N 3.34Å; I254-F504 HydrophobicContact CD1-CE2 4.25Å
255L96.2Very high93.6Very high4 Ų428.4 Ų28.42%0.02115%0.148CC..Hα-helixtrans-71.1-35.8178.9-64.3177.1000111.9C251 T252 I253 K259 F504 Q555 F558 E559C251-L255 VanDerWaalsContact O-CG 3.31Å; C251-L255 WeakPolarHBondContact O-CG 3.34Å; C251-L255 PolarHBondContact O-N 2.98Å; T252-L255 PolarHBondContact O-N 3.24Å; I253-L255 PolarHBondContact O-N 3.29Å; L255-K259 PolarHBondContact O-N 3.46Å; L255-F504 HydrophobicContact CD1-CZ 4.47Å; L255-Q555 PolarHBondContact O-NE2 2.76Å; L255-F558 HydrophobicContact CD1-CB 4.1Å; L255-F558 WeakPolarHBondContact CD1-O 3.26Å; L255-F558 HydrophobicContact CD2-CB 3.6Å; L255-F558 HydrophobicContact CD2-CG 4.22Å; L255-E559 HydrophobicContact CD1-CG 4.14Å
256E94.9Very high93.9Very high2 Ų225.7 Ų25.71%0.00913%0.131CC..Hα-helixtrans-70.2-41174.7-66.2-56.6147.400112.6T252 I253 W258 K259 R260 T609 I612T252-E256 HydrophobicContact CG2-CG 4.5Å; T252-E256 WeakPolarHBondContact O-CG 3.47Å; T252-E256 PolarHBondContact O-N 2.91Å; T252-E256 VanDerWaalsContact O-N 3.14Å; I253-E256 PolarHBondContact O-N 3.37Å; E256-W258 VanDerWaalsContact C-N 3.33Å; E256-K259 VanDerWaalsContact CD-CE 3.42Å; E256-K259 PolarHBondContact O-N 2.72Å; E256-K259 IonicContact OE1-NZ 2.59Å; E256-K259 PolarHBondContact OE1-NZ 3.1Å; E256-K259 WeakPolarHBondContact OE2-CE 3.38Å; E256-K259 IonicContact OE2-NZ 2.79Å; E256-K259 PolarHBondContact OE2-NZ 3.35Å; E256-R260 PolarHBondContact O-N 2.95Å; E256-T609 VanDerWaalsContact OE1-CB 3.3Å; E256-T609 WeakPolarHBondContact OE1-CB 3.39Å; E256-T609 WeakPolarHBondContact OE1-CG2 3.35Å; E256-T609 PolarHBondContact OE1-OG1 3.27Å; E256-I612 HydrophobicContact CB-CB 4.11Å; E256-I612 HydrophobicContact CB-CD1 3.97Å; E256-I612 HydrophobicContact CB-CG2 3.84Å; E256-I612 HydrophobicContact CG-CB 4.42Å; E256-I612 HydrophobicContact CG-CD1 4.28Å
257L96Very high94.1Very high70 Ų7024.5 Ų24.537%0.36613%0.126SC..Hα-helixtrans-67.3-34.5175.5-71.8-179.3000111.8Y214 I253 R260 S261Y214-L257 WeakPolarHBondContact OH-CB 3.42Å; I253-L257 HydrophobicContact CG2-CD1 3.59Å; I253-L257 HydrophobicContact CG2-CG 4.02Å; I253-L257 WeakPolarHBondContact O-CB 3.2Å; I253-L257 VanDerWaalsContact O-CG 3.24Å; I253-L257 WeakPolarHBondContact O-CG 3.17Å; I253-L257 PolarHBondContact O-N 3.3Å; L257-R260 PolarHBondContact O-N 3.18Å; L257-S261 PolarHBondContact O-N 3.09Å; L257-S261 PolarHBondContact O-OG 3.28Å
258W96.8Very high94.3Very high4 Ų429 Ų292%0.01515%0.146CC..Hα-helixtrans-61.7-45.1172.5175.3-117.4000112.2F211 Y214 I254 E256 R260 S261 S262 I551F211-W258 HydrophobicContact CB-CH2 3.64Å; F211-W258 HydrophobicContact CB-CZ2 3.54Å; F211-W258 HydrophobicContact CB-CZ3 4.26Å; F211-W258 AromaticContact CD2-CD1 3.85Å; F211-W258 AromaticContact CD2-CD2 3.55Å; F211-W258 HydrophobicContact CD2-CD2 3.55Å; F211-W258 AromaticContact CD2-CE2 3.37Å; F211-W258 HydrophobicContact CD2-CE3 4.05Å; F211-W258 AromaticContact CD2-CG 3.89Å; F211-W258 HydrophobicContact CD2-CG 3.89Å; F211-W258 HydrophobicContact CD2-CH2 4.25Å; F211-W258 AromaticContact CD2-CZ2 3.77Å; F211-W258 HydrophobicContact CD2-CZ2 3.77Å; F211-W258 HydrophobicContact CD2-CZ3 4.36Å; F211-W258 AromaticContact CD2-NE1 3.54Å; F211-W258 AromaticContact CE2-CD1 3.88Å; F211-W258 HydrophobicContact CE2-CD2 4.18Å; F211-W258 HydrophobicContact CE2-CG 4.02Å; F211-W258 AromaticContact CE2-NE1 3.96Å; F211-W258 HydrophobicContact CG-CH2 4.46Å; F211-W258 HydrophobicContact CG-CZ2 4.08Å; F211-W258 VanDerWaalsContact N-CH2 3.26Å; Y214-W258 HydrophobicContact CD1-CB 3.98Å; Y214-W258 HydrophobicContact CD1-CD2 4.19Å; Y214-W258 AromaticContact CD1-CE3 3.66Å; Y214-W258 HydrophobicContact CD1-CE3 3.66Å; Y214-W258 HydrophobicContact CD1-CG 4.32Å; Y214-W258 HydrophobicContact CD2-CE3 4.27Å; Y214-W258 HydrophobicContact CE1-CB 3.64Å; Y214-W258 HydrophobicContact CE1-CE3 4.44Å; Y214-W258 HydrophobicContact CE1-CG 4.44Å; Y214-W258 AromaticContact CG-CE3 3.59Å; Y214-W258 HydrophobicContact CG-CE3 3.59Å; Y214-W258 HydrophobicContact CG-CZ3 4.16Å; I254-W258 WeakPolarHBondContact O-CB 3.29Å; I254-W258 PolarHBondContact O-N 3.34Å; E256-W258 VanDerWaalsContact C-N 3.33Å; W258-R260 PolarHBondContact O-N 3.06Å; W258-S261 PolarHBondContact O-N 3.36Å; W258-S261 VanDerWaalsContact O-N 3.15Å; W258-S262 VanDerWaalsContact O-CB 3.26Å; W258-S262 WeakPolarHBondContact O-CB 3.32Å; W258-S262 PolarHBondContact O-N 2.98Å; W258-I551 HydrophobicContact CZ2-CG2 3.58Å
259K95.6Very high94.6Very high32 Ų3228.8 Ų28.814%0.13915%0.145CC..Hα-helixtrans-54.4-42.2175.9-74.5-175-71.3172.90111.7L255 E256 A263 Q555 E559 D614L255-K259 PolarHBondContact O-N 3.46Å; E256-K259 VanDerWaalsContact CD-CE 3.42Å; E256-K259 PolarHBondContact O-N 2.72Å; E256-K259 IonicContact OE1-NZ 2.59Å; E256-K259 PolarHBondContact OE1-NZ 3.1Å; E256-K259 WeakPolarHBondContact OE2-CE 3.38Å; E256-K259 IonicContact OE2-NZ 2.79Å; E256-K259 PolarHBondContact OE2-NZ 3.35Å; K259-A263 WeakPolarHBondContact O-CB 3.41Å; K259-A263 PolarHBondContact O-N 3.43Å; K259-Q555 HydrophobicContact CD-CG 4.17Å; K259-Q555 HydrophobicContact CG-CG 4.18Å; K259-E559 IonicContact NZ-OE1 2.7Å; K259-D614 CarbonylContact C-O 3.6Å; K259-D614 HydrophobicContact CB-CB 4.42Å; K259-D614 WeakPolarHBondContact CD-OD1 3.48Å; K259-D614 WeakPolarHBondContact CE-OD1 3.27Å; K259-D614 IonicContact NZ-OD1 2.93Å; K259-D614 PolarHBondContact NZ-OD1 3.09Å
260R95.8Very high94.7Very high68 Ų6827.3 Ų27.326%0.25714%0.137SC..Hα-helixtrans-66.3-43.8177.5-67.5169.562.986.4-5113.3E256 L257 W258 T264 P613 D614 P616E256-R260 PolarHBondContact O-N 2.95Å; L257-R260 PolarHBondContact O-N 3.18Å; W258-R260 PolarHBondContact O-N 3.06Å; R260-T264 PolarHBondContact O-N 3.32Å; R260-T264 VanDerWaalsContact O-N 3.15Å; R260-T264 PolarHBondContact O-OG1 3.49Å; R260-P613 WeakPolarHBondContact CD-O 3.33Å; R260-P613 WeakPolarHBondContact CG-O 3.29Å; R260-P613 PolarHBondContact NH1-O 3.04Å; R260-D614 WeakPolarHBondContact CA-O 3.49Å; R260-D614 WeakPolarHBondContact CG-O 3.45Å; R260-D614 PolarHBondContact N-O 3.5Å; R260-P616 HydrophobicContact CB-CG 4.32Å
261S94.6Very high94.5Very high49 Ų4925 Ų2534%0.34313%0.129SC..Hα-helixtrans-66.1-45.8176.5-64.30000111L257 W258 A263 T264 L265L257-S261 PolarHBondContact O-N 3.09Å; L257-S261 PolarHBondContact O-OG 3.28Å; W258-S261 PolarHBondContact O-N 3.36Å; W258-S261 VanDerWaalsContact O-N 3.15Å; S261-A263 PolarHBondContact O-N 2.92Å; S261-T264 WeakPolarHBondContact O-CA 3.32Å; S261-T264 WeakPolarHBondContact O-CB 3.48Å; S261-T264 PolarHBondContact O-N 3.3Å; S261-L265 WeakPolarHBondContact O-CG 3.41Å; S261-L265 PolarHBondContact O-N 3.41Å
262S95.7Very high94.3Very high5 Ų527.1 Ų27.14%0.03514%0.14CC..Hα-helixtrans-59.5-43.8176.9-176.50000111.7W258 T264 L265 A266W258-S262 VanDerWaalsContact O-CB 3.26Å; W258-S262 WeakPolarHBondContact O-CB 3.32Å; W258-S262 PolarHBondContact O-N 2.98Å; S262-T264 VanDerWaalsContact C-N 3.28Å; S262-T264 PolarHBondContact O-N 3.06Å; S262-L265 PolarHBondContact O-N 2.8Å; S262-A266 VanDerWaalsContact O-CB 3.26Å; S262-A266 WeakPolarHBondContact O-CB 3.38Å; S262-A266 PolarHBondContact O-N 3.37Å
263A95.1Very high93.9Very high7 Ų727.9 Ų27.96%0.05815%0.146CC..Hα-helixtrans-62.7-34.2174.300000112.8K259 S261 Y267 V615K259-A263 WeakPolarHBondContact O-CB 3.41Å; K259-A263 PolarHBondContact O-N 3.43Å; S261-A263 PolarHBondContact O-N 2.92Å; A263-Y267 VanDerWaalsContact O-CB 3.3Å; A263-Y267 WeakPolarHBondContact O-CB 3.37Å; A263-Y267 PolarHBondContact O-N 2.89Å; A263-V615 HydrophobicContact CB-CG1 4.43Å; A263-V615 HydrophobicContact CB-CG2 4.17Å
264T95.2Very high93.3Very high55 Ų5528 Ų2834%0.33714%0.143SC..Hα-helixtrans-67.9-46.9176.2-54.20000111.7R260 S261 S262 Y267 H268 I619R260-T264 PolarHBondContact O-N 3.32Å; R260-T264 VanDerWaalsContact O-N 3.15Å; R260-T264 PolarHBondContact O-OG1 3.49Å; S261-T264 WeakPolarHBondContact O-CA 3.32Å; S261-T264 WeakPolarHBondContact O-CB 3.48Å; S261-T264 PolarHBondContact O-N 3.3Å; S262-T264 VanDerWaalsContact C-N 3.28Å; S262-T264 PolarHBondContact O-N 3.06Å; T264-Y267 PolarHBondContact O-N 2.83Å; T264-H268 WeakPolarHBondContact O-CB 3.07Å; T264-H268 PolarHBondContact O-N 2.92Å; T264-I619 VanDerWaalsContact CA-CD1 3.44Å; T264-I619 HydrophobicContact CG2-CD1 4.22Å
265L95.1Very high92.4Very high35 Ų3534.4 Ų34.418%0.18317%0.171CC..Hα-helixtrans-61.6-49.7175-66.1173.5000111L194 S261 S262 Y267 H268 W269L194-L265 HydrophobicContact CD1-CD1 4.37Å; L194-L265 HydrophobicContact CD1-CD2 4.46Å; S261-L265 WeakPolarHBondContact O-CG 3.41Å; S261-L265 PolarHBondContact O-N 3.41Å; S262-L265 PolarHBondContact O-N 2.8Å; L265-Y267 VanDerWaalsContact C-N 3.31Å; L265-Y267 PolarHBondContact O-N 2.81Å; L265-H268 PolarHBondContact O-N 3.4Å; L265-H268 VanDerWaalsContact O-N 3.17Å; L265-W269 HydrophobicContact CB-CD2 4.37Å; L265-W269 HydrophobicContact CB-CE3 4.31Å; L265-W269 HydrophobicContact CB-CH2 4.06Å; L265-W269 HydrophobicContact CB-CZ2 4.11Å; L265-W269 HydrophobicContact CB-CZ3 4.17Å; L265-W269 HydrophobicContact CD1-CH2 4.19Å; L265-W269 HydrophobicContact CD1-CZ2 4.5Å; L265-W269 HydrophobicContact CD2-CH2 4.4Å; L265-W269 HydrophobicContact CD2-CZ2 3.91Å; L265-W269 HydrophobicContact CG-CH2 4.45Å; L265-W269 HydrophobicContact CG-CZ2 4.39Å; L265-W269 WeakPolarHBondContact O-CB 3.31Å; L265-W269 PolarHBondContact O-N 3.5Å
266A94.4Very high91.3Very high0 Ų039 Ų390%019%0.191CC..Hα-helixtrans-63.9-32.9-179.500000113.4S262 G270 T271 L272 A549S262-A266 VanDerWaalsContact O-CB 3.26Å; S262-A266 WeakPolarHBondContact O-CB 3.38Å; S262-A266 PolarHBondContact O-N 3.37Å; A266-G270 CarbonylContact O-C 3.57Å; A266-G270 PolarHBondContact O-N 3.33Å; A266-T271 PolarHBondContact O-N 3.35Å; A266-T271 PolarHBondContact O-OG1 3.07Å; A266-L272 HydrophobicContact CB-CB 3.9Å; A266-L272 HydrophobicContact CB-CD1 4.48Å; A266-L272 PolarHBondContact O-N 3.3Å; A266-A549 HydrophobicContact CB-CB 4.26Å; A266-A549 VanDerWaalsContact CB-O 3.24Å; A266-A549 WeakPolarHBondContact CB-O 3.36Å
267Y93.9Very high89.9Confident21 Ų2141.7 Ų41.78%0.08221%0.214CC..Hα-helixtrans-67.9-48.4172.5-179.9-91.6000111M94 A263 T264 L265 W269 G270 L272 I619 K622 L623M94-Y267 HydrophobicContact CB-CE2 4.32Å; M94-Y267 HydrophobicContact CG-CD1 4.46Å; M94-Y267 HydrophobicContact CG-CE1 3.82Å; M94-Y267 HydrophobicContact CG-CE2 4.21Å; A263-Y267 VanDerWaalsContact O-CB 3.3Å; A263-Y267 WeakPolarHBondContact O-CB 3.37Å; A263-Y267 PolarHBondContact O-N 2.89Å; T264-Y267 PolarHBondContact O-N 2.83Å; L265-Y267 VanDerWaalsContact C-N 3.31Å; L265-Y267 PolarHBondContact O-N 2.81Å; Y267-W269 PolarHBondContact O-N 3.41Å; Y267-G270 PolarHBondContact O-N 3.2Å; Y267-L272 HydrophobicContact CD2-CD2 4.43Å; Y267-I619 HydrophobicContact CD2-CG2 3.73Å; Y267-I619 HydrophobicContact CG-CD1 4.45Å; Y267-I619 HydrophobicContact CG-CG1 4.47Å; Y267-I619 HydrophobicContact CG-CG2 3.85Å; Y267-K622 HydrophobicContact CE1-CD 3.68Å; Y267-K622 HydrophobicContact CE2-CB 4.03Å; Y267-K622 HydrophobicContact CE2-CD 4.4Å; Y267-K622 VanDerWaalsContact OH-CD 3.28Å; Y267-K622 WeakPolarHBondContact OH-CD 3.27Å; Y267-L623 HydrophobicContact CD2-CD2 4.24Å; Y267-L623 HydrophobicContact CE2-CD2 4.31Å
268H92.2Very high89Confident100 Ų10043.4 Ų43.446%0.46322%0.219SC..Hα-helixtrans-61-36.2178.6-172.5-164.2000111.6T264 L265 G270T264-H268 WeakPolarHBondContact O-CB 3.07Å; T264-H268 PolarHBondContact O-N 2.92Å; L265-H268 PolarHBondContact O-N 3.4Å; L265-H268 VanDerWaalsContact O-N 3.17Å; H268-G270 VanDerWaalsContact C-N 3.33Å
269W93.1Very high88.1Confident3 Ų345.1 Ų45.11%0.01123%0.227CC..Hα-helixtrans-81.6-10.7177.4-58.4-16.1000113.8L194 D195 R198 E203 A206 L207 L265 Y267 T271L194-W269 HydrophobicContact CB-CZ2 4.34Å; D195-W269 PolarHBondContact OD1-NE1 3.07Å; R198-W269 HydrophobicContact CB-CZ2 4.41Å; R198-W269 HydrophobicContact CG-CD2 4.04Å; R198-W269 HydrophobicContact CG-CE3 4.45Å; R198-W269 HydrophobicContact CG-CG 4.25Å; R198-W269 VanDerWaalsContact CZ-CB 3.48Å; R198-W269 VanDerWaalsContact NH1-CD1 3.34Å; R198-W269 PolarHBondContact NH2-O 2.95Å; E203-W269 HydrophobicContact CB-CE3 3.97Å; E203-W269 HydrophobicContact CB-CZ3 4.43Å; E203-W269 HydrophobicContact CG-CB 3.91Å; E203-W269 HydrophobicContact CG-CD2 4.23Å; E203-W269 HydrophobicContact CG-CE3 3.8Å; E203-W269 HydrophobicContact CG-CG 4.32Å; A206-W269 HydrophobicContact CB-CH2 3.58Å; A206-W269 HydrophobicContact CB-CZ2 4.16Å; A206-W269 HydrophobicContact CB-CZ3 3.99Å; L207-W269 HydrophobicContact CD2-CE3 4.47Å; L207-W269 HydrophobicContact CD2-CH2 4.29Å; L207-W269 HydrophobicContact CD2-CZ3 3.65Å; L207-W269 HydrophobicContact CG-CZ3 3.75Å; L265-W269 HydrophobicContact CB-CD2 4.37Å; L265-W269 HydrophobicContact CB-CE3 4.31Å; L265-W269 HydrophobicContact CB-CH2 4.06Å; L265-W269 HydrophobicContact CB-CZ2 4.11Å; L265-W269 HydrophobicContact CB-CZ3 4.17Å; L265-W269 HydrophobicContact CD1-CH2 4.19Å; L265-W269 HydrophobicContact CD1-CZ2 4.5Å; L265-W269 HydrophobicContact CD2-CH2 4.4Å; L265-W269 HydrophobicContact CD2-CZ2 3.91Å; L265-W269 HydrophobicContact CG-CH2 4.45Å; L265-W269 HydrophobicContact CG-CZ2 4.39Å; L265-W269 WeakPolarHBondContact O-CB 3.31Å; L265-W269 PolarHBondContact O-N 3.5Å; Y267-W269 PolarHBondContact O-N 3.41Å; W269-T271 VanDerWaalsContact C-N 3.27Å; W269-T271 PolarHBondContact O-N 3.11Å
270G91.4Very high87.5Confident4 Ų446.6 Ų46.64%0.04123%0.234CC..THydrogen-bonded Turntrans81.5-2.1178.100000114.6F86 A266 Y267 H268F86-G270 VanDerWaalsContact CB-O 3.28Å; F86-G270 WeakPolarHBondContact CB-O 3.09Å; A266-G270 CarbonylContact O-C 3.57Å; A266-G270 PolarHBondContact O-N 3.33Å; Y267-G270 PolarHBondContact O-N 3.2Å; H268-G270 VanDerWaalsContact C-N 3.33Å
271T92.1Very high87Confident14 Ų1443.8 Ų43.89%0.08623%0.225CC..  trans-75.6-23.4179.755.30000113.2E203 A266 W269 S273 R274 P547 A548E203-T271 HydrophobicContact CB-CG2 4.12Å; E203-T271 HydrophobicContact CG-CG2 3.64Å; A266-T271 PolarHBondContact O-N 3.35Å; A266-T271 PolarHBondContact O-OG1 3.07Å; W269-T271 VanDerWaalsContact C-N 3.27Å; W269-T271 PolarHBondContact O-N 3.11Å; T271-S273 VanDerWaalsContact C-N 3.33Å; T271-S273 PolarHBondContact O-N 3.41Å; T271-R274 WeakPolarHBondContact O-CB 3.17Å; T271-R274 PolarHBondContact O-N 2.94Å; T271-P547 HydrophobicContact CG2-CB 4.2Å; T271-A548 VanDerWaalsContact CB-O 3.3Å; T271-A548 WeakPolarHBondContact CB-O 3.47Å; T271-A548 PolarHBondContact OG1-O 3.01Å
272L89.2Confident86.7Confident48 Ų4842.3 Ų42.325%0.25121%0.212SC..THydrogen-bonded Turntrans-63.4-36.7179.9-173.563.5000113A266 Y267 R274 I619 L623A266-L272 HydrophobicContact CB-CB 3.9Å; A266-L272 HydrophobicContact CB-CD1 4.48Å; A266-L272 PolarHBondContact O-N 3.3Å; Y267-L272 HydrophobicContact CD2-CD2 4.43Å; L272-R274 VanDerWaalsContact C-N 3.3Å; L272-R274 PolarHBondContact O-N 3.27Å; L272-I619 HydrophobicContact CD2-CG2 3.98Å; L272-L623 HydrophobicContact CD2-CD1 4Å
273S83.9Confident86Confident18 Ų1843.2 Ų43.213%0.12622%0.218CC..THydrogen-bonded Turntrans-83.5-4.7-177.4-60.30000113.3F86 T271F86-S273 VanDerWaalsContact CE1-CB 3.45Å; T271-S273 VanDerWaalsContact C-N 3.33Å; T271-S273 PolarHBondContact O-N 3.41Å
274R82.8Confident85.5Confident47 Ų4743.1 Ų43.118%0.17722%0.217CC..  trans-76.7126.6-177.5-161.3173.4107.1163.81.4110.8Y123 T271 L272 K276 E279Y123-R274 PolarHBondContact OH-NH1 3Å; T271-R274 WeakPolarHBondContact O-CB 3.17Å; T271-R274 PolarHBondContact O-N 2.94Å; L272-R274 VanDerWaalsContact C-N 3.3Å; L272-R274 PolarHBondContact O-N 3.27Å; R274-K276 PolarHBondContact O-N 3.3Å; R274-E279 IonicContact CZ-OE1 2.83Å; R274-E279 IonicContact NE-OE1 2.68Å; R274-E279 PolarHBondContact NE-OE1 2.95Å; R274-E279 IonicContact NH2-OE1 2.72Å; R274-E279 PolarHBondContact NH2-OE1 2.9Å
275K77.5Confident85.2Confident136 Ų13641.1 Ų41.159%0.59120%0.203SC*.  trans-87.2110-178.9-67.7-175.5-178.8179.10111.1A277 F278K275-A277 PolarHBondContact O-N 3.29Å; K275-F278 HydrophobicContact CB-CD2 3.73Å; K275-F278 HydrophobicContact CB-CE2 3.9Å; K275-F278 HydrophobicContact CB-CG 4.41Å; K275-F278 HydrophobicContact CD-CD2 4.26Å; K275-F278 HydrophobicContact CD-CE2 3.54Å; K275-F278 HydrophobicContact CD-CZ 4Å; K275-F278 HydrophobicContact CG-CE2 4.28Å; K275-F278 PolarHBondContact O-N 2.99Å; K275-F278 VanDerWaalsContact O-N 3.1Å
276K71.3Confident84.8Confident100 Ų10042.8 Ų42.844%0.43521%0.21SC..G310 helixtrans-54.7-26.9176.8-64.3-175.3-179.7-178.10114.2R274 F278 E279R274-K276 PolarHBondContact O-N 3.3Å; K276-F278 PolarHBondContact O-N 3.38Å; K276-E279 WeakPolarHBondContact O-CB 3.48Å; K276-E279 PolarHBondContact O-N 3.44Å
277A65.8Low84.4Confident60 Ų6044 Ų4450%0.49622%0.223SC..G310 helixtrans-64.7-22.6179.900000113.8K275K275-A277 PolarHBondContact O-N 3.29Å
278F77.3Confident84.1Confident106 Ų10648.6 Ų48.647%0.46525%0.253SS..G310 helixtrans-94.8-0.9179.8-53.5-33.3000113K275 K276 V294 T295K275-F278 HydrophobicContact CB-CD2 3.73Å; K275-F278 HydrophobicContact CB-CE2 3.9Å; K275-F278 HydrophobicContact CB-CG 4.41Å; K275-F278 HydrophobicContact CD-CD2 4.26Å; K275-F278 HydrophobicContact CD-CE2 3.54Å; K275-F278 HydrophobicContact CD-CZ 4Å; K275-F278 HydrophobicContact CG-CE2 4.28Å; K275-F278 PolarHBondContact O-N 2.99Å; K275-F278 VanDerWaalsContact O-N 3.1Å; K276-F278 PolarHBondContact O-N 3.38Å; F278-V294 HydrophobicContact CD1-CG1 4.44Å; F278-V294 HydrophobicContact CE1-CG1 3.99Å; F278-T295 HydrophobicContact CD1-CG2 3.95Å
279E79.1Confident83.8Confident40 Ų4046.7 Ų46.719%0.18725%0.246CC..PPolyproline II helixtrans-70.3142.5178-66.4-179.7175.500111R274 K276 R388 L389R274-E279 IonicContact CZ-OE1 2.83Å; R274-E279 IonicContact NE-OE1 2.68Å; R274-E279 PolarHBondContact NE-OE1 2.95Å; R274-E279 IonicContact NH2-OE1 2.72Å; R274-E279 PolarHBondContact NH2-OE1 2.9Å; K276-E279 WeakPolarHBondContact O-CB 3.48Å; K276-E279 PolarHBondContact O-N 3.44Å; E279-R388 PolarHBondContact O-NH1 3.15Å; E279-R388 PolarHBondContact O-NH2 3.26Å; E279-L389 HydrophobicContact CB-CD2 3.83Å
280E81.9Confident83.5Confident62 Ų6247.2 Ų47.229%0.2925%0.252SS..PPolyproline II helixtrans-68.4152.9177.2-69.5-152.4176.600112.5T131 R133T131-E280 WeakPolarHBondContact CB-OE2 3.47Å; T131-E280 VanDerWaalsContact CG2-CD 3.42Å; T131-E280 WeakPolarHBondContact CG2-OE2 3.37Å; R133-E280 IonicContact NH2-OE2 2.86Å
281P86.1Confident83.3Confident10 Ų1054.5 Ų54.57%0.06528%0.28CS..PPolyproline II helixtrans-61.5140.2171.6-17.930.3000111.5F285 E299 R388P281-F285 HydrophobicContact CB-CB 4.1Å; P281-F285 HydrophobicContact CB-CD1 3.56Å; P281-F285 HydrophobicContact CB-CE1 4.32Å; P281-F285 HydrophobicContact CB-CG 4.19Å; P281-F285 HydrophobicContact CG-CD1 4.24Å; P281-E299 VanDerWaalsContact CD-OE2 3.31Å; P281-E299 WeakPolarHBondContact CD-OE2 3.49Å; P281-E299 HydrophobicContact CG-CB 4.21Å; P281-E299 HydrophobicContact CG-CG 4.5Å; P281-E299 VanDerWaalsContact CG-OE2 3.29Å; P281-E299 WeakPolarHBondContact CG-OE2 3.21Å; P281-R388 CarbonylContact C-O 3.48Å; P281-R388 VanDerWaalsContact CA-O 3.28Å; P281-R388 WeakPolarHBondContact CA-O 3.24Å; P281-R388 HydrophobicContact CB-CG 3.99Å; P281-R388 HydrophobicContact CG-CG 4.2Å
282R87.6Confident83Confident18 Ų1854.5 Ų54.57%0.06828%0.279CS..PPolyproline II helixtrans-58.8151.5175.473.3176.4-160.6116.713.2110.5G284 F285 E383 H387 R388 E390R282-G284 PolarHBondContact O-N 3.32Å; R282-F285 HydrophobicContact CG-CB 4.11Å; R282-F285 VanDerWaalsContact O-CB 3.29Å; R282-F285 WeakPolarHBondContact O-CB 3.39Å; R282-F285 PolarHBondContact O-N 2.91Å; R282-E383 IonicContact CZ-OE1 3.46Å; R282-E383 IonicContact CZ-OE2 3.72Å; R282-E383 VanDerWaalsContact CZ-OE2 3.27Å; R282-E383 IonicContact NH1-OE1 3.28Å; R282-E383 IonicContact NH1-OE2 3.3Å; R282-E383 PolarHBondContact NH1-OE2 2.84Å; R282-E383 IonicContact NH2-OE1 2.78Å; R282-E383 PolarHBondContact NH2-OE1 2.84Å; R282-E383 IonicContact NH2-OE2 3.33Å; R282-E383 PolarHBondContact NH2-OE2 2.88Å; R282-H387 PolarHBondContact NE-O 3.2Å; R282-R388 PolarHBondContact N-O 2.93Å; R282-E390 HydrophobicContact CB-CB 4.29Å; R282-E390 WeakPolarHBondContact CD-OE2 3.49Å
283P81.4Confident82.9Confident24 Ų2457.7 Ų57.716%0.15630%0.303CS..THydrogen-bonded Turntrans-58.2-29.3-175.9-2533.6000114.4E130 R156 F285E130-P283 HydrophobicContact CB-CG 3.94Å; E130-P283 HydrophobicContact CG-CG 3.77Å; R156-P283 HydrophobicContact CB-CB 3.76Å; R156-P283 WeakPolarHBondContact CB-O 3.46Å; R156-P283 HydrophobicContact CG-CB 4.24Å; R156-P283 VanDerWaalsContact CG-O 3.31Å; R156-P283 WeakPolarHBondContact CG-O 3.39Å; P283-F285 VanDerWaalsContact C-N 3.33Å
284G83.8Confident82.9Confident4 Ų461.3 Ų61.34%0.04132%0.324CS..THydrogen-bonded Turntrans-72.2-19.1176.800000115R282R282-G284 PolarHBondContact O-N 3.32Å
285F88.4Confident83Confident13 Ų1360.7 Ų60.76%0.05733%0.325CS..  trans-66.4138.9-178.1-174.4-120.5000111.6P281 R282 P283 P300 Y302 N386 H387 R388P281-F285 HydrophobicContact CB-CB 4.1Å; P281-F285 HydrophobicContact CB-CD1 3.56Å; P281-F285 HydrophobicContact CB-CE1 4.32Å; P281-F285 HydrophobicContact CB-CG 4.19Å; P281-F285 HydrophobicContact CG-CD1 4.24Å; R282-F285 HydrophobicContact CG-CB 4.11Å; R282-F285 VanDerWaalsContact O-CB 3.29Å; R282-F285 WeakPolarHBondContact O-CB 3.39Å; R282-F285 PolarHBondContact O-N 2.91Å; P283-F285 VanDerWaalsContact C-N 3.33Å; F285-P300 HydrophobicContact CD1-CB 4.23Å; F285-P300 HydrophobicContact CE1-CB 4.33Å; F285-P300 WeakPolarHBondContact CE1-O 3.39Å; F285-Y302 HydrophobicContact CE2-CG 4.46Å; F285-N386 VanDerWaalsContact CD2-OD1 3.29Å; F285-N386 WeakPolarHBondContact CD2-OD1 3.47Å; F285-H387 WeakPolarHBondContact CD2-O 3.41Å; F285-R388 HydrophobicContact CD1-CB 4.44Å; F285-R388 HydrophobicContact CD1-CG 4.18Å; F285-R388 HydrophobicContact CD2-CB 4.18Å; F285-R388 HydrophobicContact CE1-CB 4.12Å; F285-R388 HydrophobicContact CE1-CG 3.88Å; F285-R388 HydrophobicContact CE2-CB 3.93Å; F285-R388 HydrophobicContact CG-CB 4.43Å; F285-R388 HydrophobicContact CZ-CB 3.89Å; F285-R388 HydrophobicContact CZ-CG 4.13Å
286H86.7Confident83.3Confident70 Ų7060.1 Ų60.132%0.32433%0.329SS..  trans-141.9148.2179.856.660.3000112N386H286-N386 VanDerWaalsContact CE1-CG 3.46Å; H286-N386 PolarHBondContact N-OD1 2.87Å; H286-N386 VanDerWaalsContact N-OD1 3.13Å; H286-N386 PolarHBondContact ND1-ND2 3.09Å; H286-N386 PolarHBondContact O-ND2 3.47Å
287G87.4Confident83.8Confident26 Ų2660.9 Ų60.927%0.26833%0.329SS..  trans-175.4-173.1-173.300000111.8L301G287-L301 CarbonylContact C-O 3.58Å; G287-L301 VanDerWaalsContact CA-O 3.23Å; G287-L301 WeakPolarHBondContact CA-O 3.3Å
288V87.4Confident84.6Confident117 Ų11763.8 Ų63.871%0.70933%0.332SS*.EExtended strand (participates in β ladder)trans-82135.6171.5-179.20000107.9G290 P300 L301V288-G290 PolarHBondContact O-N 3.42Å; V288-P300 CarbonylContact O-C 3.55Å; V288-L301 PolarHBondContact N-O 2.86Å; V288-L301 PolarHBondContact O-N 3.24Å
289L84.9Confident85Confident60 Ų6059.5 Ų59.531%0.31431%0.314SS..EExtended strand (participates in β ladder)trans-64.5132.8178.5-161.463.5000110.3P150 E298P150-L289 HydrophobicContact CB-CD2 4.12Å; L289-E298 HydrophobicContact CD1-CG 3.81Å; L289-E298 HydrophobicContact CD2-CG 4.08Å; L289-E298 WeakPolarHBondContact CD2-OE1 3.19Å; L289-E298 HydrophobicContact CG-CG 3.72Å
290G86.7Confident85.4Confident15 Ų1558.1 Ų58.116%0.15531%0.308CS..EExtended strand (participates in β ladder)trans-165.9-179.3176.300000111.6V288 E298 E299V288-G290 PolarHBondContact O-N 3.42Å; G290-E298 WeakPolarHBondContact O-CA 3.28Å; G290-E299 PolarHBondContact N-O 3.47Å; G290-E299 PolarHBondContact O-N 3.47Å
291Y87.6Confident85.7Confident157 Ų15758.4 Ų58.462%0.61631%0.312SS*.EExtended strand (participates in β ladder)trans-91.5131.3179.9-64.6-79.3000111E298Y291-E298 HydrophobicContact CD1-CB 4.38Å; Y291-E298 HydrophobicContact CE1-CB 4.14Å
292N86Confident86Confident13 Ų1359.6 Ų59.67%0.0732%0.315CS..  trans-70.4124.7171.8-178.1-40.5000109.5V294 T295 D296 R297 E299N292-V294 PolarHBondContact O-N 3.17Å; N292-V294 VanDerWaalsContact O-N 3.1Å; N292-V294 WeakPolarHBondContact OD1-CB 3.5Å; N292-V294 PolarHBondContact OD1-N 3.5Å; N292-T295 WeakPolarHBondContact CB-OG1 3.32Å; N292-T295 PolarHBondContact O-N 3.39Å; N292-T295 PolarHBondContact OD1-N 3.47Å; N292-D296 VanDerWaalsContact O-CA 3.23Å; N292-D296 WeakPolarHBondContact O-CA 3.49Å; N292-D296 PolarHBondContact O-N 2.87Å; N292-R297 PolarHBondContact N-O 3.07Å; N292-E299 HydrophobicContact CB-CG 4.02Å; N292-E299 PolarHBondContact ND2-OE1 3.01Å
293P86.8Confident86.3Confident116 Ų11662 Ų6275%0.75333%0.333SS*.THydrogen-bonded Turntrans-69-10-175.729.5-37000114.5
294V85.5Confident86.8Confident94 Ų9465.8 Ų65.857%0.5735%0.352SS*.THydrogen-bonded Turntrans-99.3-41.8-179.9-178.50000111.5F278 N292F278-V294 HydrophobicContact CD1-CG1 4.44Å; F278-V294 HydrophobicContact CE1-CG1 3.99Å; N292-V294 PolarHBondContact O-N 3.17Å; N292-V294 VanDerWaalsContact O-N 3.1Å; N292-V294 WeakPolarHBondContact OD1-CB 3.5Å; N292-V294 PolarHBondContact OD1-N 3.5Å
295T83.5Confident87.3Confident33 Ų3368.9 Ų68.920%0.20238%0.377CS..THydrogen-bonded Turntrans-106.8-10-173.858.60000113.7F278 N292 R297F278-T295 HydrophobicContact CD1-CG2 3.95Å; N292-T295 WeakPolarHBondContact CB-OG1 3.32Å; N292-T295 PolarHBondContact O-N 3.39Å; N292-T295 PolarHBondContact OD1-N 3.47Å; T295-R297 PolarHBondContact O-N 3.32Å
296D84.1Confident87.7Confident125 Ų12574.2 Ų74.267%0.66840%0.4SS*.  trans53.515.3-170.8-67.7-41.6000114.4N292N292-D296 VanDerWaalsContact O-CA 3.23Å; N292-D296 WeakPolarHBondContact O-CA 3.49Å; N292-D296 PolarHBondContact O-N 2.87Å
297R81.8Confident88.1Confident115 Ų11572.7 Ų72.743%0.43439%0.392SS..  trans-79.5141.7175.6-63.5-179-173.3-175.60.2109.9N292 T295 E299N292-R297 PolarHBondContact N-O 3.07Å; T295-R297 PolarHBondContact O-N 3.32Å; R297-E299 PolarHBondContact O-N 2.86Å
298E83.2Confident88.5Confident121 Ų12175.1 Ų75.157%0.56540%0.396SS*.EExtended strand (participates in β ladder)trans-74.6114.3172.5-171.4176.6-153.400109.5L289 G290 Y291L289-E298 HydrophobicContact CD1-CG 3.81Å; L289-E298 HydrophobicContact CD2-CG 4.08Å; L289-E298 WeakPolarHBondContact CD2-OE1 3.19Å; L289-E298 HydrophobicContact CG-CG 3.72Å; G290-E298 WeakPolarHBondContact O-CA 3.28Å; Y291-E298 HydrophobicContact CD1-CB 4.38Å; Y291-E298 HydrophobicContact CE1-CB 4.14Å
299E85.7Confident88.9Confident16 Ų1674.2 Ų74.28%0.07539%0.387CS..EExtended strand (participates in β ladder)trans-145.4161.1-179.365.9175-153.500111.8P281 G290 N292 R297 L301 R388P281-E299 VanDerWaalsContact CD-OE2 3.31Å; P281-E299 WeakPolarHBondContact CD-OE2 3.49Å; P281-E299 HydrophobicContact CG-CB 4.21Å; P281-E299 HydrophobicContact CG-CG 4.5Å; P281-E299 VanDerWaalsContact CG-OE2 3.29Å; P281-E299 WeakPolarHBondContact CG-OE2 3.21Å; G290-E299 PolarHBondContact N-O 3.47Å; G290-E299 PolarHBondContact O-N 3.47Å; N292-E299 HydrophobicContact CB-CG 4.02Å; N292-E299 PolarHBondContact ND2-OE1 3.01Å; R297-E299 PolarHBondContact O-N 2.86Å; E299-L301 HydrophobicContact CG-CD2 4.25Å; E299-L301 PolarHBondContact O-N 2.91Å; E299-R388 IonicContact OE1-CZ 2.72Å; E299-R388 IonicContact OE1-NE 3.56Å; E299-R388 PolarHBondContact OE1-NE 2.94Å; E299-R388 IonicContact OE1-NH2 2.91Å; E299-R388 PolarHBondContact OE1-NH2 3.14Å; E299-R388 VanDerWaalsContact OE1-NH2 3.08Å; E299-R388 IonicContact OE2-CZ 2.95Å; E299-R388 IonicContact OE2-NE 3.27Å; E299-R388 IonicContact OE2-NH2 2.91Å; E299-R388 PolarHBondContact OE2-NH2 2.98Å
300P86.4Confident89.4Confident12 Ų1274.5 Ų74.58%0.07838%0.384CS..EExtended strand (participates in β ladder)trans-61.3135.9171.5-20.432.6000110.5F285 V288F285-P300 HydrophobicContact CD1-CB 4.23Å; F285-P300 HydrophobicContact CE1-CB 4.33Å; F285-P300 WeakPolarHBondContact CE1-O 3.39Å; V288-P300 CarbonylContact O-C 3.55Å
301L89.5Confident89.8Confident68 Ų6874.7 Ų74.736%0.35638%0.381SS..EExtended strand (participates in β ladder)trans-115137.3176.7-60.7179000110.5G287 V288 E299G287-L301 CarbonylContact C-O 3.58Å; G287-L301 VanDerWaalsContact CA-O 3.23Å; G287-L301 WeakPolarHBondContact CA-O 3.3Å; V288-L301 PolarHBondContact N-O 2.86Å; V288-L301 PolarHBondContact O-N 3.24Å; E299-L301 HydrophobicContact CG-CD2 4.25Å; E299-L301 PolarHBondContact O-N 2.91Å
302Y91.6Very high90.2Very high35 Ų3574 Ų7414%0.13738%0.378CS..  trans-130.9126.4179.2-169.2-93.9000111.2F285 N304 K306 R307 R310 N386F285-Y302 HydrophobicContact CE2-CG 4.46Å; Y302-N304 PolarHBondContact O-N 3.4Å; Y302-K306 HydrophobicContact CE1-CB 3.93Å; Y302-R307 HydrophobicContact CD1-CB 4.21Å; Y302-R307 HydrophobicContact CE1-CB 3.86Å; Y302-R310 PolarHBondContact OH-NE 2.74Å; Y302-R310 PolarHBondContact OH-NH2 2.95Å; Y302-N386 WeakPolarHBondContact CD2-ND2 3.25Å; Y302-N386 VanDerWaalsContact CG-ND2 3.35Å
303P94.1Very high90.7Very high68 Ų6879.1 Ų79.144%0.44241%0.405SS..  trans-60.9126.5-178.2-24.934.2000113.2A305 K306 R307P303-A305 VanDerWaalsContact C-N 3.32Å; P303-A305 PolarHBondContact O-N 3.48Å; P303-K306 HydrophobicContact CB-CB 4.42Å; P303-K306 HydrophobicContact CB-CD 4.25Å; P303-K306 HydrophobicContact CB-CG 4.15Å; P303-K306 HydrophobicContact CG-CD 4.12Å; P303-K306 PolarHBondContact O-N 3.47Å; P303-R307 PolarHBondContact O-N 3.19Å
304N92.2Very high91.2Very high103 Ų10376.9 Ų76.955%0.55139%0.389SS*.Hα-helixtrans-60.4-38.9-179.8-71.8-20.5000112.7Y302 K306 R307 Q308Y302-N304 PolarHBondContact O-N 3.4Å; N304-K306 VanDerWaalsContact C-N 3.33Å; N304-K306 PolarHBondContact O-N 3.35Å; N304-R307 WeakPolarHBondContact O-CB 3.49Å; N304-R307 PolarHBondContact O-N 3.15Å; N304-R307 VanDerWaalsContact O-N 3.15Å; N304-R307 VanDerWaalsContact OD1-CZ 3.3Å; N304-R307 PolarHBondContact OD1-NH1 2.83Å; N304-R307 PolarHBondContact OD1-NH2 2.97Å; N304-Q308 WeakPolarHBondContact O-CG 3.29Å; N304-Q308 PolarHBondContact O-N 3.33Å
305A94.9Very high91.7Very high69 Ų6972.6 Ų72.657%0.5736%0.363SS*.Hα-helixtrans-59.6-41.6178.300000112.4P303 R307 Q308 L309P303-A305 VanDerWaalsContact C-N 3.32Å; P303-A305 PolarHBondContact O-N 3.48Å; A305-R307 VanDerWaalsContact C-N 3.33Å; A305-R307 PolarHBondContact O-N 2.97Å; A305-Q308 PolarHBondContact O-N 3.24Å; A305-L309 VanDerWaalsContact O-CG 3.27Å; A305-L309 WeakPolarHBondContact O-CG 3.32Å; A305-L309 PolarHBondContact O-N 2.91Å
306K95.4Very high92.3Very high126 Ų12674.8 Ų74.855%0.54837%0.373SS..Hα-helixtrans-62.1-42.1176.4-69.4-175.3-179.5-179.10111.2Y302 P303 N304 L309 R310Y302-K306 HydrophobicContact CE1-CB 3.93Å; P303-K306 HydrophobicContact CB-CB 4.42Å; P303-K306 HydrophobicContact CB-CD 4.25Å; P303-K306 HydrophobicContact CB-CG 4.15Å; P303-K306 HydrophobicContact CG-CD 4.12Å; P303-K306 PolarHBondContact O-N 3.47Å; N304-K306 VanDerWaalsContact C-N 3.33Å; N304-K306 PolarHBondContact O-N 3.35Å; K306-L309 PolarHBondContact O-N 2.93Å; K306-R310 WeakPolarHBondContact O-CG 3.32Å; K306-R310 PolarHBondContact O-N 2.93Å; K306-R310 VanDerWaalsContact O-N 3.11Å
307R95.1Very high93Very high38 Ų3871.7 Ų71.714%0.14336%0.36CS..Hα-helixtrans-63.7-47177.1-177.3167.968.4-101.7-5.2111.3Y302 P303 N304 A305 L309 R310 I311 E385Y302-R307 HydrophobicContact CD1-CB 4.21Å; Y302-R307 HydrophobicContact CE1-CB 3.86Å; P303-R307 PolarHBondContact O-N 3.19Å; N304-R307 WeakPolarHBondContact O-CB 3.49Å; N304-R307 PolarHBondContact O-N 3.15Å; N304-R307 VanDerWaalsContact O-N 3.15Å; N304-R307 VanDerWaalsContact OD1-CZ 3.3Å; N304-R307 PolarHBondContact OD1-NH1 2.83Å; N304-R307 PolarHBondContact OD1-NH2 2.97Å; A305-R307 VanDerWaalsContact C-N 3.33Å; A305-R307 PolarHBondContact O-N 2.97Å; R307-L309 VanDerWaalsContact C-N 3.32Å; R307-L309 PolarHBondContact O-N 3.26Å; R307-R310 WeakPolarHBondContact O-CB 3.13Å; R307-R310 PolarHBondContact O-N 3.49Å; R307-R310 VanDerWaalsContact O-N 3.14Å; R307-I311 HydrophobicContact CG-CD1 3.95Å; R307-I311 WeakPolarHBondContact O-CG1 3.41Å; R307-I311 PolarHBondContact O-N 3.37Å; R307-E385 WeakPolarHBondContact CG-O 2.97Å
308Q95.2Very high93.7Very high76 Ų7669.8 Ų69.836%0.35536%0.355SS..Hα-helixtrans-63.1-39.1179.6-65.1-60-5.700112.1N304 A305 R310 I311 Y312N304-Q308 WeakPolarHBondContact O-CG 3.29Å; N304-Q308 PolarHBondContact O-N 3.33Å; A305-Q308 PolarHBondContact O-N 3.24Å; Q308-R310 VanDerWaalsContact C-N 3.34Å; Q308-R310 PolarHBondContact O-N 3.43Å; Q308-I311 PolarHBondContact O-N 3.42Å; Q308-Y312 HydrophobicContact CB-CD2 4.26Å; Q308-Y312 HydrophobicContact CB-CE2 4.34Å; Q308-Y312 VanDerWaalsContact O-CD2 3.23Å; Q308-Y312 WeakPolarHBondContact O-CD2 3.35Å; Q308-Y312 PolarHBondContact O-N 2.83Å; Q308-Y312 VanDerWaalsContact OE1-CE2 3.28Å
309L96.1Very high94.3Very high99 Ų9964.7 Ų64.752%0.51833%0.332SS..Hα-helixtrans-60.8-42173.3-70.5168.6000112.1A305 K306 R307 I311 L313A305-L309 VanDerWaalsContact O-CG 3.27Å; A305-L309 WeakPolarHBondContact O-CG 3.32Å; A305-L309 PolarHBondContact O-N 2.91Å; K306-L309 PolarHBondContact O-N 2.93Å; R307-L309 VanDerWaalsContact C-N 3.32Å; R307-L309 PolarHBondContact O-N 3.26Å; L309-I311 VanDerWaalsContact C-N 3.34Å; L309-I311 PolarHBondContact O-N 3.47Å; L309-L313 HydrophobicContact CB-CD1 4.4Å; L309-L313 HydrophobicContact CD2-CD1 3.7Å; L309-L313 HydrophobicContact CD2-CG 4.43Å; L309-L313 WeakPolarHBondContact O-CB 3.32Å; L309-L313 WeakPolarHBondContact O-CG 3.19Å; L309-L313 PolarHBondContact O-N 3.45Å
310R96.1Very high94.8Very high66 Ų6668.7 Ų68.725%0.24935%0.353CS..Hα-helixtrans-60.2-43.5174.8-71.7-172.8179.2-169.2-2.4112.3Y302 K306 R307 Q308 V314 S315 W384Y302-R310 PolarHBondContact OH-NE 2.74Å; Y302-R310 PolarHBondContact OH-NH2 2.95Å; K306-R310 WeakPolarHBondContact O-CG 3.32Å; K306-R310 PolarHBondContact O-N 2.93Å; K306-R310 VanDerWaalsContact O-N 3.11Å; R307-R310 WeakPolarHBondContact O-CB 3.13Å; R307-R310 PolarHBondContact O-N 3.49Å; R307-R310 VanDerWaalsContact O-N 3.14Å; Q308-R310 VanDerWaalsContact C-N 3.34Å; Q308-R310 PolarHBondContact O-N 3.43Å; R310-V314 WeakPolarHBondContact O-CB 3.2Å; R310-V314 PolarHBondContact O-N 2.75Å; R310-S315 PolarHBondContact O-N 3.33Å; R310-S315 VanDerWaalsContact O-N 3.14Å; R310-W384 HydrophobicContact CB-CE3 4.06Å; R310-W384 HydrophobicContact CB-CH2 3.84Å; R310-W384 HydrophobicContact CB-CZ3 3.38Å; R310-W384 HydrophobicContact CG-CE3 4.16Å; R310-W384 HydrophobicContact CG-CH2 3.4Å; R310-W384 HydrophobicContact CG-CZ2 4.04Å; R310-W384 HydrophobicContact CG-CZ3 3.47Å; R310-W384 VanDerWaalsContact CG-CZ3 3.47Å; R310-W384 PolarHBondContact NH1-O 2.97Å
311I94.8Very high95.3Very high18 Ų1872.6 Ų72.69%0.09237%0.373CS..Iπ-helixtrans-65.8-56.5179.5-65.8167.6000110.2R307 Q308 L309 S315 L316 E385R307-I311 HydrophobicContact CG-CD1 3.95Å; R307-I311 WeakPolarHBondContact O-CG1 3.41Å; R307-I311 PolarHBondContact O-N 3.37Å; Q308-I311 PolarHBondContact O-N 3.42Å; L309-I311 VanDerWaalsContact C-N 3.34Å; L309-I311 PolarHBondContact O-N 3.47Å; I311-S315 VanDerWaalsContact O-CB 3.25Å; I311-S315 WeakPolarHBondContact O-CB 3.23Å; I311-S315 PolarHBondContact O-N 3.19Å; I311-L316 PolarHBondContact O-N 3.02Å; I311-E385 HydrophobicContact CG1-CB 4.39Å; I311-E385 HydrophobicContact CG1-CG 3.82Å
312Y96.3Very high95.6Very high144 Ų14470.3 Ų70.357%0.56536%0.362SS*.Iπ-helixtrans-77.6-29.4-170.9-68.9-63.4000114.6Q308 L316 P317Q308-Y312 HydrophobicContact CB-CD2 4.26Å; Q308-Y312 HydrophobicContact CB-CE2 4.34Å; Q308-Y312 VanDerWaalsContact O-CD2 3.23Å; Q308-Y312 WeakPolarHBondContact O-CD2 3.35Å; Q308-Y312 PolarHBondContact O-N 2.83Å; Q308-Y312 VanDerWaalsContact OE1-CE2 3.28Å; Y312-L316 HydrophobicContact CD1-CD2 4.17Å; Y312-P317 VanDerWaalsContact O-CD 3.29Å; Y312-P317 WeakPolarHBondContact O-CD 3.41Å
313L97.2Very high95.8Very high120 Ų12069.4 Ų69.463%0.62836%0.36SS*.Iπ-helixtrans-98.2-17.1-175.2-58.4179.9000114.3L309L309-L313 HydrophobicContact CB-CD1 4.4Å; L309-L313 HydrophobicContact CD2-CD1 3.7Å; L309-L313 HydrophobicContact CD2-CG 4.43Å; L309-L313 WeakPolarHBondContact O-CB 3.32Å; L309-L313 WeakPolarHBondContact O-CG 3.19Å; L309-L313 PolarHBondContact O-N 3.45Å
314V97.2Very high95.9Very high69 Ų6973.2 Ų73.242%0.41837%0.366SS..Iπ-helixtrans-121.5-55.3-179.7-177.80000110.4R310 F318 L381 W384R310-V314 WeakPolarHBondContact O-CB 3.2Å; R310-V314 PolarHBondContact O-N 2.75Å; V314-F318 VanDerWaalsContact O-CB 3.28Å; V314-F318 WeakPolarHBondContact O-CB 3.31Å; V314-F318 PolarHBondContact O-N 2.96Å; V314-F318 VanDerWaalsContact O-N 3.07Å; V314-L381 HydrophobicContact CG1-CD1 4.31Å; V314-W384 HydrophobicContact CB-CH2 4.25Å; V314-W384 HydrophobicContact CB-CZ3 3.98Å; V314-W384 HydrophobicContact CG1-CH2 4.4Å; V314-W384 HydrophobicContact CG1-CZ3 4.12Å; V314-W384 HydrophobicContact CG2-CH2 3.94Å; V314-W384 HydrophobicContact CG2-CZ3 4.18Å
315S95.6Very high96Very high3 Ų372.2 Ų72.22%0.02136%0.36CS..Iπ-helixtrans-67.9-50.5-171.3-172.30000112.7R310 I311 F318 V319 L381 E385 K400R310-S315 PolarHBondContact O-N 3.33Å; R310-S315 VanDerWaalsContact O-N 3.14Å; I311-S315 VanDerWaalsContact O-CB 3.25Å; I311-S315 WeakPolarHBondContact O-CB 3.23Å; I311-S315 PolarHBondContact O-N 3.19Å; S315-F318 WeakPolarHBondContact O-CB 3.22Å; S315-F318 PolarHBondContact O-N 3.48Å; S315-V319 WeakPolarHBondContact O-CG2 3.34Å; S315-V319 PolarHBondContact O-N 3.04Å; S315-L381 VanDerWaalsContact OG-CD2 3.3Å; S315-L381 WeakPolarHBondContact OG-CD2 3.38Å; S315-L381 WeakPolarHBondContact OG-CG 3.22Å; S315-E385 WeakPolarHBondContact CB-OE1 3.21Å; S315-E385 PolarHBondContact OG-OE1 3.35Å; S315-K400 WeakPolarHBondContact OG-CE 3.4Å
316L96.1Very high96Very high80 Ų8069.1 Ų69.142%0.41934%0.335SS..Hα-helixtrans-62.3-48.4178.6176.467.6000112.9I311 Y312 F318 V319 L320I311-L316 PolarHBondContact O-N 3.02Å; Y312-L316 HydrophobicContact CD1-CD2 4.17Å; L316-F318 VanDerWaalsContact C-N 3.29Å; L316-F318 PolarHBondContact O-N 3.32Å; L316-V319 PolarHBondContact O-N 3.03Å; L316-L320 HydrophobicContact CD1-CD1 4.41Å; L316-L320 HydrophobicContact CD1-CG 4.34Å; L316-L320 HydrophobicContact CG-CD1 4.25Å; L316-L320 WeakPolarHBondContact O-CG 3.4Å; L316-L320 PolarHBondContact O-N 3.08Å
317P97.8Very high95.9Very high60 Ų6066.2 Ų66.239%0.3933%0.325SS..Hα-helixtrans-59-37.3174.4-28.236.9000113.7Y312 L320 L321Y312-P317 VanDerWaalsContact O-CD 3.29Å; Y312-P317 WeakPolarHBondContact O-CD 3.41Å; P317-L320 PolarHBondContact O-N 3.41Å; P317-L321 WeakPolarHBondContact O-CB 3.44Å; P317-L321 PolarHBondContact O-N 3.04Å
318F97.1Very high95.8Very high75 Ų7570.8 Ų70.833%0.32934%0.343SS..Hα-helixtrans-63-46.6175.3176.2-95.3000111.8V314 S315 L316 L320 L321 C322 Y374 A377 L381V314-F318 VanDerWaalsContact O-CB 3.28Å; V314-F318 WeakPolarHBondContact O-CB 3.31Å; V314-F318 PolarHBondContact O-N 2.96Å; V314-F318 VanDerWaalsContact O-N 3.07Å; S315-F318 WeakPolarHBondContact O-CB 3.22Å; S315-F318 PolarHBondContact O-N 3.48Å; L316-F318 VanDerWaalsContact C-N 3.29Å; L316-F318 PolarHBondContact O-N 3.32Å; F318-L320 PolarHBondContact O-N 2.97Å; F318-L321 WeakPolarHBondContact O-CB 3.29Å; F318-L321 PolarHBondContact O-N 3.11Å; F318-C322 PolarHBondContact O-N 3.15Å; F318-C322 PolarHBondContact O-SG 3.2Å; F318-C322 VanDerWaalsContact O-SG 3.42Å; F318-Y374 HydrophobicContact CE1-CE2 4.37Å; F318-A377 HydrophobicContact CE1-CB 3.97Å; F318-A377 HydrophobicContact CZ-CB 3.79Å; F318-L381 HydrophobicContact CB-CD2 4.37Å; F318-L381 HydrophobicContact CD1-CD2 3.64Å; F318-L381 HydrophobicContact CE1-CD2 4.33Å; F318-L381 HydrophobicContact CG-CD2 4.25Å
319V96.3Very high95.8Very high14 Ų1469.1 Ų69.19%0.08534%0.338CS..Hα-helixtrans-58.4-48.1175.7173.80000110.6S315 L316 L321 C322 L323 Y374 K400S315-V319 WeakPolarHBondContact O-CG2 3.34Å; S315-V319 PolarHBondContact O-N 3.04Å; L316-V319 PolarHBondContact O-N 3.03Å; V319-L321 VanDerWaalsContact C-N 3.31Å; V319-L321 PolarHBondContact O-N 3.24Å; V319-C322 WeakPolarHBondContact O-CB 3.37Å; V319-C322 PolarHBondContact O-N 2.79Å; V319-C322 VanDerWaalsContact O-N 3.15Å; V319-L323 HydrophobicContact CG1-CD1 4.25Å; V319-L323 HydrophobicContact CG1-CG 4.43Å; V319-L323 WeakPolarHBondContact O-CG 3.38Å; V319-L323 PolarHBondContact O-N 3.39Å; V319-Y374 WeakPolarHBondContact CG2-OH 3.17Å; V319-K400 HydrophobicContact CG2-CB 4.5Å; V319-K400 HydrophobicContact CG2-CD 4.36Å; V319-K400 HydrophobicContact CG2-CG 4.03Å
320L96.4Very high95.6Very high100 Ų10064.9 Ų64.952%0.52432%0.316SS..Hα-helixtrans-60.8-38.8178.9-67.5174000112.6L316 P317 F318 L323 Y324L316-L320 HydrophobicContact CD1-CD1 4.41Å; L316-L320 HydrophobicContact CD1-CG 4.34Å; L316-L320 HydrophobicContact CG-CD1 4.25Å; L316-L320 WeakPolarHBondContact O-CG 3.4Å; L316-L320 PolarHBondContact O-N 3.08Å; P317-L320 PolarHBondContact O-N 3.41Å; F318-L320 PolarHBondContact O-N 2.97Å; L320-L323 HydrophobicContact CD2-CD1 4.45Å; L320-L323 PolarHBondContact O-N 3.26Å; L320-Y324 PolarHBondContact O-N 3.01Å
321L96.5Very high95.5Very high94 Ų9465 Ų6549%0.49232%0.32SS..Hα-helixtrans-62.3-45.5174176.564.6000111.4P317 F318 V319 L323 Y324 L325P317-L321 WeakPolarHBondContact O-CB 3.44Å; P317-L321 PolarHBondContact O-N 3.04Å; F318-L321 WeakPolarHBondContact O-CB 3.29Å; F318-L321 PolarHBondContact O-N 3.11Å; V319-L321 VanDerWaalsContact C-N 3.31Å; V319-L321 PolarHBondContact O-N 3.24Å; L321-L323 VanDerWaalsContact C-N 3.32Å; L321-L323 PolarHBondContact O-N 3.35Å; L321-Y324 PolarHBondContact O-N 3.25Å; L321-L325 HydrophobicContact CD1-CD1 4.47Å; L321-L325 HydrophobicContact CD1-CG 4.45Å; L321-L325 HydrophobicContact CG-CD1 4.24Å; L321-L325 WeakPolarHBondContact O-CG 3.36Å; L321-L325 PolarHBondContact O-N 2.97Å
322C96.3Very high95.5Very high19 Ų1967.1 Ų67.113%0.12833%0.331CS..Hα-helixtrans-62.2-38.8176.8-69.50000112.3F318 V319 L325 S326 Y374 F404F318-C322 PolarHBondContact O-N 3.15Å; F318-C322 PolarHBondContact O-SG 3.2Å; F318-C322 VanDerWaalsContact O-SG 3.42Å; V319-C322 WeakPolarHBondContact O-CB 3.37Å; V319-C322 PolarHBondContact O-N 2.79Å; V319-C322 VanDerWaalsContact O-N 3.15Å; C322-L325 PolarHBondContact O-N 3.05Å; C322-S326 PolarHBondContact O-N 2.72Å; C322-Y374 HydrophobicContact CB-CD2 3.83Å; C322-Y374 HydrophobicContact CB-CE2 3.67Å; C322-F404 HydrophobicContact CB-CD2 4.18Å; C322-F404 HydrophobicContact CB-CE2 4.03Å
323L95.7Very high95.3Very high17 Ų1761.1 Ų61.19%0.08931%0.307CS..Hα-helixtrans-64-43.5174.8-66177.3000111.9V319 L320 L321 L325 S326 L327 V403 F404 F407V319-L323 HydrophobicContact CG1-CD1 4.25Å; V319-L323 HydrophobicContact CG1-CG 4.43Å; V319-L323 WeakPolarHBondContact O-CG 3.38Å; V319-L323 PolarHBondContact O-N 3.39Å; L320-L323 HydrophobicContact CD2-CD1 4.45Å; L320-L323 PolarHBondContact O-N 3.26Å; L321-L323 VanDerWaalsContact C-N 3.32Å; L321-L323 PolarHBondContact O-N 3.35Å; L323-L325 PolarHBondContact O-N 3.41Å; L323-S326 WeakPolarHBondContact O-CB 3.5Å; L323-S326 PolarHBondContact O-N 2.8Å; L323-L327 WeakPolarHBondContact O-CG 3.48Å; L323-L327 PolarHBondContact O-N 3.42Å; L323-V403 HydrophobicContact CD1-CG1 3.83Å; L323-V403 HydrophobicContact CD2-CG1 4.19Å; L323-F404 HydrophobicContact CD2-CD2 4.18Å; L323-F407 HydrophobicContact CD1-CD2 4.33Å; L323-F407 HydrophobicContact CD1-CE2 4.29Å; L323-F407 HydrophobicContact CD2-CB 3.78Å; L323-F407 HydrophobicContact CD2-CD2 3.75Å; L323-F407 HydrophobicContact CD2-CG 3.8Å
324Y95.6Very high95Very high148 Ų14856.4 Ų56.458%0.5828%0.282SS*.Hα-helixtrans-60.5-44.7174.7170.5-100.7000112.1L320 L321 S326 L327 Y328L320-Y324 PolarHBondContact O-N 3.01Å; L321-Y324 PolarHBondContact O-N 3.25Å; Y324-S326 VanDerWaalsContact C-N 3.32Å; Y324-S326 PolarHBondContact O-N 3.26Å; Y324-L327 PolarHBondContact O-N 2.92Å; Y324-Y328 PolarHBondContact O-N 2.9Å
325L94.9Very high94.8Very high81 Ų8159.6 Ų59.642%0.42429%0.292SS..Hα-helixtrans-62.8-38.7177.3-70.7172.6000112.1L321 C322 L323 Y328 V329L321-L325 HydrophobicContact CD1-CD1 4.47Å; L321-L325 HydrophobicContact CD1-CG 4.45Å; L321-L325 HydrophobicContact CG-CD1 4.24Å; L321-L325 WeakPolarHBondContact O-CG 3.36Å; L321-L325 PolarHBondContact O-N 2.97Å; C322-L325 PolarHBondContact O-N 3.05Å; L323-L325 PolarHBondContact O-N 3.41Å; L325-Y328 WeakPolarHBondContact O-CB 3.5Å; L325-Y328 PolarHBondContact O-N 3.38Å; L325-V329 WeakPolarHBondContact O-CG2 3.34Å; L325-V329 PolarHBondContact O-N 2.83Å
326S93.7Very high94.6Very high5 Ų562.5 Ų62.54%0.03531%0.306CS..Hα-helixtrans-59.3-49.2173.3163.10000112.2C322 L323 Y324 Y328 V329 M330 N408C322-S326 PolarHBondContact O-N 2.72Å; L323-S326 WeakPolarHBondContact O-CB 3.5Å; L323-S326 PolarHBondContact O-N 2.8Å; Y324-S326 VanDerWaalsContact C-N 3.32Å; Y324-S326 PolarHBondContact O-N 3.26Å; S326-Y328 PolarHBondContact O-N 3.28Å; S326-V329 PolarHBondContact O-N 2.83Å; S326-V329 VanDerWaalsContact O-N 3.15Å; S326-M330 PolarHBondContact O-N 2.68Å; S326-N408 WeakPolarHBondContact CB-OD1 3.37Å; S326-N408 PolarHBondContact OG-OD1 3.24Å
327L93.5Very high94.2Very high65 Ų6560.3 Ų60.334%0.3429%0.294SS..Hα-helixtrans-59.9-37.4176.2-68.6174.6000111.9L323 Y324 M330 M331 A411L323-L327 WeakPolarHBondContact O-CG 3.48Å; L323-L327 PolarHBondContact O-N 3.42Å; Y324-L327 PolarHBondContact O-N 2.92Å; L327-M330 HydrophobicContact CD2-CE 4.32Å; L327-M330 WeakPolarHBondContact O-CB 3.23Å; L327-M330 PolarHBondContact O-N 3.17Å; L327-M331 WeakPolarHBondContact O-CG 3.04Å; L327-M331 PolarHBondContact O-N 2.84Å; L327-A411 HydrophobicContact CD2-CB 3.8Å
328Y94.5Very high93.9Very high134 Ų13459.3 Ų59.353%0.52529%0.294SS..Hα-helixtrans-64.8-42.9175.9-176.8-105.5000112.6Y324 L325 S326 M330 M331 I332Y324-Y328 PolarHBondContact O-N 2.9Å; L325-Y328 WeakPolarHBondContact O-CB 3.5Å; L325-Y328 PolarHBondContact O-N 3.38Å; S326-Y328 PolarHBondContact O-N 3.28Å; Y328-M330 VanDerWaalsContact C-N 3.32Å; Y328-M330 PolarHBondContact O-N 3.09Å; Y328-M331 PolarHBondContact O-N 2.93Å; Y328-I332 HydrophobicContact CD1-CD1 3.88Å; Y328-I332 HydrophobicContact CE1-CD1 3.49Å; Y328-I332 VanDerWaalsContact CE1-CD1 3.49Å; Y328-I332 HydrophobicContact CE1-CG1 4.31Å; Y328-I332 PolarHBondContact O-N 3.46Å; Y328-I332 VanDerWaalsContact O-N 3.09Å
329V94.3Very high93.7Very high41 Ų4162.9 Ų62.925%0.24831%0.306CS..Hα-helixtrans-61.7-41.2174.5171.20000111.2L325 S326 M331 I332 Y333 Y363 V366 M370L325-V329 WeakPolarHBondContact O-CG2 3.34Å; L325-V329 PolarHBondContact O-N 2.83Å; S326-V329 PolarHBondContact O-N 2.83Å; S326-V329 VanDerWaalsContact O-N 3.15Å; V329-M331 VanDerWaalsContact C-N 3.33Å; V329-M331 PolarHBondContact O-N 3.4Å; V329-I332 WeakPolarHBondContact O-CB 3.48Å; V329-I332 PolarHBondContact O-N 3.47Å; V329-Y333 PolarHBondContact O-N 2.99Å; V329-Y363 HydrophobicContact CG1-CE2 4.35Å; V329-V366 HydrophobicContact CG1-CG1 3.82Å; V329-M370 HydrophobicContact CB-SD 4.3Å; V329-M370 HydrophobicContact CG1-SD 4.14Å; V329-M370 HydrophobicContact CG2-CE 4.48Å; V329-M370 HydrophobicContact CG2-SD 4.05Å
330M92.9Very high93.4Very high10 Ų1062.2 Ų62.25%0.04930%0.302CS..Hα-helixtrans-59.6-41.7174-178.6-160.775.800111.9S326 L327 Y328 I332 Y333 F334 A411 S412 Y415S326-M330 PolarHBondContact O-N 2.68Å; L327-M330 HydrophobicContact CD2-CE 4.32Å; L327-M330 WeakPolarHBondContact O-CB 3.23Å; L327-M330 PolarHBondContact O-N 3.17Å; Y328-M330 VanDerWaalsContact C-N 3.32Å; Y328-M330 PolarHBondContact O-N 3.09Å; M330-I332 VanDerWaalsContact C-N 3.34Å; M330-I332 PolarHBondContact O-N 2.95Å; M330-Y333 WeakPolarHBondContact O-CB 3.48Å; M330-Y333 PolarHBondContact O-N 3Å; M330-F334 HydrophobicContact CE-CE2 4.29Å; M330-F334 HydrophobicContact CG-CD2 4.05Å; M330-F334 HydrophobicContact CG-CE2 3.68Å; M330-F334 WeakPolarHBondContact O-CD2 3.33Å; M330-F334 PolarHBondContact O-N 3.46Å; M330-F334 VanDerWaalsContact O-N 3.12Å; M330-F334 HydrophobicContact SD-CE2 4.06Å; M330-A411 HydrophobicContact SD-CB 3.62Å; M330-S412 PolarHBondContact SD-N 3.49Å; M330-S412 VanDerWaalsContact SD-N 3.44Å; M330-Y415 HydrophobicContact CE-CD2 4.08Å; M330-Y415 HydrophobicContact CE-CG 4.26Å
331M92.8Very high93.1Very high69 Ų6961.3 Ų61.334%0.3430%0.297SS..Hα-helixtrans-64-38.1176-68.4-54.6-59.200112.5L327 Y328 V329 Y333 F334 Q335 Y415L327-M331 WeakPolarHBondContact O-CG 3.04Å; L327-M331 PolarHBondContact O-N 2.84Å; Y328-M331 PolarHBondContact O-N 2.93Å; V329-M331 VanDerWaalsContact C-N 3.33Å; V329-M331 PolarHBondContact O-N 3.4Å; M331-Y333 VanDerWaalsContact C-N 3.31Å; M331-F334 PolarHBondContact O-N 2.91Å; M331-Q335 WeakPolarHBondContact O-CG 3.35Å; M331-Q335 PolarHBondContact O-N 3.39Å; M331-Q335 VanDerWaalsContact O-N 3.08Å; M331-Y415 HydrophobicContact CE-CE2 4.16Å; M331-Y415 HydrophobicContact SD-CD2 4.33Å; M331-Y415 HydrophobicContact SD-CE2 3.83Å
332I94.5Very high92.8Very high61 Ų6159 Ų5931%0.31329%0.289SS..Hα-helixtrans-62.2-41.5173.5-66.2166.9000110.5Y328 V329 M330 F334 Q335 M336Y328-I332 HydrophobicContact CD1-CD1 3.88Å; Y328-I332 HydrophobicContact CE1-CD1 3.49Å; Y328-I332 VanDerWaalsContact CE1-CD1 3.49Å; Y328-I332 HydrophobicContact CE1-CG1 4.31Å; Y328-I332 PolarHBondContact O-N 3.46Å; Y328-I332 VanDerWaalsContact O-N 3.09Å; V329-I332 WeakPolarHBondContact O-CB 3.48Å; V329-I332 PolarHBondContact O-N 3.47Å; M330-I332 VanDerWaalsContact C-N 3.34Å; M330-I332 PolarHBondContact O-N 2.95Å; I332-F334 PolarHBondContact O-N 2.77Å; I332-Q335 WeakPolarHBondContact O-CB 3.23Å; I332-Q335 PolarHBondContact O-N 3.25Å; I332-M336 HydrophobicContact CG2-CE 4.19Å; I332-M336 HydrophobicContact CG2-CG 4.37Å; I332-M336 HydrophobicContact CG2-SD 4.38Å; I332-M336 WeakPolarHBondContact O-CG 3.45Å; I332-M336 PolarHBondContact O-N 3.19Å
333Y91.8Very high92.6Very high19 Ų1960.1 Ų60.18%0.07530%0.295CS..Hα-helixtrans-55.8-51.5175.2157.3-102.3000111.9V329 M330 M331 Q335 M336 E337 P359 Y363V329-Y333 PolarHBondContact O-N 2.99Å; M330-Y333 WeakPolarHBondContact O-CB 3.48Å; M330-Y333 PolarHBondContact O-N 3Å; M331-Y333 VanDerWaalsContact C-N 3.31Å; Y333-Q335 VanDerWaalsContact C-N 3.27Å; Y333-Q335 PolarHBondContact O-N 3.01Å; Y333-M336 WeakPolarHBondContact O-CB 3.42Å; Y333-M336 PolarHBondContact O-N 3.44Å; Y333-M336 VanDerWaalsContact O-N 3.1Å; Y333-E337 WeakPolarHBondContact CE1-OE2 3.39Å; Y333-E337 PolarHBondContact O-N 3.36Å; Y333-E337 PolarHBondContact OH-OE1 2.88Å; Y333-E337 PolarHBondContact OH-OE2 3.15Å; Y333-P359 HydrophobicContact CD2-CB 4.46Å; Y333-P359 HydrophobicContact CE2-CB 4.4Å; Y333-Y363 AromaticContact CD1-CD1 3.99Å; Y333-Y363 HydrophobicContact CD1-CD1 3.99Å; Y333-Y363 HydrophobicContact CD1-CE1 4.09Å; Y333-Y363 HydrophobicContact CD1-CG 4.28Å; Y333-Y363 VanDerWaalsContact CD2-CB 3.42Å; Y333-Y363 AromaticContact CD2-CD1 3.84Å; Y333-Y363 HydrophobicContact CD2-CD1 3.84Å; Y333-Y363 HydrophobicContact CD2-CD2 4.29Å; Y333-Y363 AromaticContact CD2-CG 3.6Å; Y333-Y363 HydrophobicContact CD2-CG 3.6Å; Y333-Y363 HydrophobicContact CE1-CD1 4.26Å; Y333-Y363 HydrophobicContact CE1-CE1 4.44Å; Y333-Y363 HydrophobicContact CE2-CD1 4.09Å; Y333-Y363 HydrophobicContact CE2-CG 4.24Å; Y333-Y363 AromaticContact CG-CD1 3.77Å; Y333-Y363 HydrophobicContact CG-CD1 3.77Å; Y333-Y363 AromaticContact CG-CD2 3.91Å; Y333-Y363 HydrophobicContact CG-CD2 3.91Å; Y333-Y363 HydrophobicContact CG-CE1 4.24Å; Y333-Y363 HydrophobicContact CG-CE2 4.37Å; Y333-Y363 AromaticContact CG-CG 3.6Å; Y333-Y363 HydrophobicContact CG-CG 3.6Å
334F90.8Very high92.4Very high21 Ų2161.6 Ų61.69%0.09230%0.301CS..Hα-helixtrans-63.3-33.3179-75.9-62.2000112.8M330 M331 I332 G338 Y415 I416 M420M330-F334 HydrophobicContact CE-CE2 4.29Å; M330-F334 HydrophobicContact CG-CD2 4.05Å; M330-F334 HydrophobicContact CG-CE2 3.68Å; M330-F334 WeakPolarHBondContact O-CD2 3.33Å; M330-F334 PolarHBondContact O-N 3.46Å; M330-F334 VanDerWaalsContact O-N 3.12Å; M330-F334 HydrophobicContact SD-CE2 4.06Å; M331-F334 PolarHBondContact O-N 2.91Å; I332-F334 PolarHBondContact O-N 2.77Å; F334-G338 PolarHBondContact O-N 3.46Å; F334-Y415 HydrophobicContact CD1-CD1 4.21Å; F334-Y415 HydrophobicContact CD1-CE1 4.13Å; F334-Y415 AromaticContact CD2-CD1 3.57Å; F334-Y415 HydrophobicContact CD2-CD1 3.57Å; F334-Y415 AromaticContact CD2-CE1 3.68Å; F334-Y415 HydrophobicContact CD2-CE1 3.68Å; F334-Y415 HydrophobicContact CD2-CG 4.13Å; F334-Y415 AromaticContact CE1-CD1 3.88Å; F334-Y415 HydrophobicContact CE1-CD1 3.88Å; F334-Y415 HydrophobicContact CE1-CE1 4.25Å; F334-Y415 AromaticContact CE2-CD1 3.18Å; F334-Y415 HydrophobicContact CE2-CD1 3.18Å; F334-Y415 AromaticContact CE2-CE1 3.81Å; F334-Y415 HydrophobicContact CE2-CE1 3.81Å; F334-Y415 AromaticContact CE2-CG 3.59Å; F334-Y415 HydrophobicContact CE2-CG 3.59Å; F334-Y415 HydrophobicContact CG-CD1 4.08Å; F334-Y415 AromaticContact CG-CE1 3.85Å; F334-Y415 HydrophobicContact CG-CE1 3.85Å; F334-Y415 AromaticContact CZ-CD1 3.36Å; F334-Y415 HydrophobicContact CZ-CD1 3.36Å; F334-Y415 HydrophobicContact CZ-CE1 4.1Å; F334-Y415 HydrophobicContact CZ-CG 4.05Å; F334-I416 HydrophobicContact CE1-CG1 4.12Å; F334-I416 HydrophobicContact CZ-CG1 4.05Å; F334-M420 HydrophobicContact CD1-CE 4.07Å; F334-M420 HydrophobicContact CD1-SD 4.49Å; F334-M420 HydrophobicContact CE1-CE 3.52Å; F334-M420 HydrophobicContact CE1-SD 4.47Å; F334-M420 HydrophobicContact CZ-CE 4.21Å
335Q92.9Very high92.2Very high136 Ų13660.7 Ų60.764%0.63631%0.306SS*.Hα-helixtrans-65.9-42173-72175.4-2.800112.2M331 I332 Y333 W339M331-Q335 WeakPolarHBondContact O-CG 3.35Å; M331-Q335 PolarHBondContact O-N 3.39Å; M331-Q335 VanDerWaalsContact O-N 3.08Å; I332-Q335 WeakPolarHBondContact O-CB 3.23Å; I332-Q335 PolarHBondContact O-N 3.25Å; Y333-Q335 VanDerWaalsContact C-N 3.27Å; Y333-Q335 PolarHBondContact O-N 3.01Å; Q335-W339 WeakPolarHBondContact O-CB 3.45Å; Q335-W339 PolarHBondContact O-N 3.3Å
336M91.8Very high92.1Very high63 Ų6363.6 Ų63.631%0.3132%0.318SS..Hα-helixtrans-65.7-40.1176.1-69.9-172.2-60.900112I332 Y333 W339 A340 P359I332-M336 HydrophobicContact CG2-CE 4.19Å; I332-M336 HydrophobicContact CG2-CG 4.37Å; I332-M336 HydrophobicContact CG2-SD 4.38Å; I332-M336 WeakPolarHBondContact O-CG 3.45Å; I332-M336 PolarHBondContact O-N 3.19Å; Y333-M336 WeakPolarHBondContact O-CB 3.42Å; Y333-M336 PolarHBondContact O-N 3.44Å; Y333-M336 VanDerWaalsContact O-N 3.1Å; M336-W339 PolarHBondContact O-N 3.26Å; M336-A340 WeakPolarHBondContact O-CB 3.38Å; M336-A340 PolarHBondContact O-N 3.19Å; M336-P359 HydrophobicContact CB-CB 4.1Å; M336-P359 HydrophobicContact CB-CG 4.31Å
337E89.1Confident91.9Very high35 Ų3569 Ų6916%0.16435%0.346CS..Hα-helixtrans-63.8-47.9176.5-175.8169.7-152.100111.3Y333 W339 A340 L341 P359Y333-E337 WeakPolarHBondContact CE1-OE2 3.39Å; Y333-E337 PolarHBondContact O-N 3.36Å; Y333-E337 PolarHBondContact OH-OE1 2.88Å; Y333-E337 PolarHBondContact OH-OE2 3.15Å; E337-W339 VanDerWaalsContact C-N 3.31Å; E337-W339 PolarHBondContact O-N 2.91Å; E337-A340 PolarHBondContact O-N 2.52Å; E337-L341 HydrophobicContact CG-CD1 4.29Å; E337-L341 WeakPolarHBondContact O-CG 3.23Å; E337-L341 PolarHBondContact O-N 2.96Å; E337-P359 HydrophobicContact CB-CB 4.49Å
338G89.9Confident91.6Very high39 Ų3970.9 Ų70.940%0.40236%0.362SS..Hα-helixtrans-61-37.817500000113.1F334 S342F334-G338 PolarHBondContact O-N 3.46Å; G338-S342 PolarHBondContact O-N 2.77Å
339W93.6Very high91.5Very high149 Ų14967.1 Ų67.156%0.56436%0.356SS*.Hα-helixtrans-64.9-46.4173.2171.276000112Q335 M336 E337 L341 S342 V343 L355Q335-W339 WeakPolarHBondContact O-CB 3.45Å; Q335-W339 PolarHBondContact O-N 3.3Å; M336-W339 PolarHBondContact O-N 3.26Å; E337-W339 VanDerWaalsContact C-N 3.31Å; E337-W339 PolarHBondContact O-N 2.91Å; W339-L341 VanDerWaalsContact C-N 3.32Å; W339-L341 PolarHBondContact O-N 3.48Å; W339-S342 PolarHBondContact O-N 3.01Å; W339-S342 VanDerWaalsContact O-N 3.16Å; W339-S342 PolarHBondContact O-OG 2.84Å; W339-V343 HydrophobicContact CD2-CG2 4.47Å; W339-V343 HydrophobicContact CZ2-CG2 4.14Å; W339-V343 WeakPolarHBondContact O-CG2 3.47Å; W339-V343 PolarHBondContact O-N 2.82Å; W339-V343 VanDerWaalsContact O-N 3.1Å; W339-L355 HydrophobicContact CH2-CD2 4.35Å; W339-L355 HydrophobicContact CZ3-CD1 4.18Å; W339-L355 HydrophobicContact CZ3-CD2 4.33Å
340A90.1Very high91.3Very high1 Ų172.7 Ų72.71%0.00838%0.377CS..Hα-helixtrans-60.7-41.9178.700000112M336 E337 V343 H344 L355 L356 P359M336-A340 WeakPolarHBondContact O-CB 3.38Å; M336-A340 PolarHBondContact O-N 3.19Å; E337-A340 PolarHBondContact O-N 2.52Å; A340-V343 PolarHBondContact O-N 2.7Å; A340-H344 PolarHBondContact O-N 3.18Å; A340-H344 VanDerWaalsContact O-N 3.09Å; A340-L355 HydrophobicContact CB-CG 4.17Å; A340-L356 HydrophobicContact CB-CD2 4.41Å; A340-P359 HydrophobicContact CB-CG 3.91Å
341L89.5Confident91.1Very high80 Ų8081.7 Ų81.742%0.41941%0.411SS..Hα-helixtrans-59.4-47.8172.8-75.3163.6000111.4E337 W339 V343 H344 D345 L356E337-L341 HydrophobicContact CG-CD1 4.29Å; E337-L341 WeakPolarHBondContact O-CG 3.23Å; E337-L341 PolarHBondContact O-N 2.96Å; W339-L341 VanDerWaalsContact C-N 3.32Å; W339-L341 PolarHBondContact O-N 3.48Å; L341-V343 PolarHBondContact O-N 3.05Å; L341-H344 PolarHBondContact O-N 3.46Å; L341-D345 PolarHBondContact O-N 3.49Å; L341-L356 HydrophobicContact CB-CD2 4.48Å; L341-L356 HydrophobicContact CD2-CD2 3.69Å; L341-L356 HydrophobicContact CG-CD2 4Å
342S91.5Very high90.8Very high47 Ų4779.2 Ų79.233%0.32940%0.399SS..Hα-helixtrans-60.9-32.1-179.975.60000113.8G338 W339 Q346G338-S342 PolarHBondContact O-N 2.77Å; W339-S342 PolarHBondContact O-N 3.01Å; W339-S342 VanDerWaalsContact O-N 3.16Å; W339-S342 PolarHBondContact O-OG 2.84Å; S342-Q346 VanDerWaalsContact O-CG 3.26Å; S342-Q346 WeakPolarHBondContact O-CG 3.46Å; S342-Q346 PolarHBondContact O-N 2.5Å
343V91.6Very high90.4Very high41 Ų4177.2 Ų77.225%0.24839%0.394CS..Hα-helixtrans-74.7-37.6176.11730000111W339 A340 L341 D347 T352 L355W339-V343 HydrophobicContact CD2-CG2 4.47Å; W339-V343 HydrophobicContact CZ2-CG2 4.14Å; W339-V343 WeakPolarHBondContact O-CG2 3.47Å; W339-V343 PolarHBondContact O-N 2.82Å; W339-V343 VanDerWaalsContact O-N 3.1Å; A340-V343 PolarHBondContact O-N 2.7Å; L341-V343 PolarHBondContact O-N 3.05Å; V343-D347 PolarHBondContact O-N 3.1Å; V343-T352 HydrophobicContact CG1-CG2 3.94Å; V343-L355 HydrophobicContact CB-CD2 4.19Å; V343-L355 HydrophobicContact CG1-CD2 3.92Å
344H90.4Very high90.2Very high49 Ų4979.2 Ų79.223%0.22741%0.408CS..Hα-helixtrans-68-40.3176.2-175.163.8000112.7A340 L341 Q346 D347 P348 T352 G353 L356A340-H344 PolarHBondContact O-N 3.18Å; A340-H344 VanDerWaalsContact O-N 3.09Å; L341-H344 PolarHBondContact O-N 3.46Å; H344-Q346 VanDerWaalsContact C-N 3.3Å; H344-Q346 PolarHBondContact O-N 3.2Å; H344-D347 CarbonylContact O-C 3.35Å; H344-P348 WeakPolarHBondContact O-CA 3.35Å; H344-T352 PolarHBondContact ND1-OG1 2.94Å; H344-G353 PolarHBondContact ND1-N 3.2Å; H344-L356 HydrophobicContact CB-CD1 4.36Å; H344-L356 HydrophobicContact CB-CD2 3.91Å; H344-L356 HydrophobicContact CB-CG 4.24Å
345D91.7Very high90.1Very high128 Ų12879.9 Ų79.968%0.68441%0.412SS*.Hα-helixtrans-66.4-31.8177.7-75.7-12.4000112.5L341L341-D345 PolarHBondContact O-N 3.49Å
346Q92.7Very high89.7Confident143 Ų14375.6 Ų75.667%0.66839%0.394SS*.Hα-helixtrans-72.5-48.3176.7-75.8173.425.700112.2S342 H344S342-Q346 VanDerWaalsContact O-CG 3.26Å; S342-Q346 WeakPolarHBondContact O-CG 3.46Å; S342-Q346 PolarHBondContact O-N 2.5Å; H344-Q346 VanDerWaalsContact C-N 3.3Å; H344-Q346 PolarHBondContact O-N 3.2Å
347D89.5Confident89.3Confident118 Ų11880.4 Ų80.463%0.63141%0.409SS*.SBendtrans-133.786.8-178.4-76.4-44.1000110.7V343 H344 S349 T352V343-D347 PolarHBondContact O-N 3.1Å; H344-D347 CarbonylContact O-C 3.35Å; D347-S349 PolarHBondContact O-N 3.39Å; D347-T352 WeakPolarHBondContact O-CG2 3.2Å; D347-T352 PolarHBondContact O-OG1 3.08Å
348P88.3Confident89.1Confident104 Ų10482.3 Ų82.368%0.67542%0.42SS*.  trans-70.1104.5179.926.9-32.9000109.6H344H344-P348 WeakPolarHBondContact O-CA 3.35Å
349S92.3Very high89.1Confident55 Ų5580.7 Ų80.739%0.38540%0.402SS..  trans-136.2164.3-179.871.20000109.7D347 W351 T352 G353D347-S349 PolarHBondContact O-N 3.39Å; S349-W351 PolarHBondContact O-N 3Å; S349-T352 PolarHBondContact N-OG1 3.19Å; S349-T352 PolarHBondContact O-N 3.29Å; S349-T352 PolarHBondContact O-OG1 3.12Å; S349-T352 VanDerWaalsContact O-OG1 3.06Å; S349-T352 WeakPolarHBondContact OG-CG2 3.48Å; S349-T352 PolarHBondContact OG-N 3.41Å; S349-T352 PolarHBondContact OG-OG1 2.87Å; S349-T352 VanDerWaalsContact OG-OG1 3.12Å; S349-G353 PolarHBondContact O-N 3.32Å
350F88.9Confident88.6Confident158 Ų15875.8 Ų75.869%0.69339%0.391SS*.Hα-helixtrans-54.7-42.6175.6176.7-96.7000112.1G353 V354F350-G353 PolarHBondContact O-N 2.78Å; F350-V354 HydrophobicContact CD1-CG2 4.5Å; F350-V354 HydrophobicContact CE1-CG2 4.04Å; F350-V354 HydrophobicContact CZ-CG2 4.12Å; F350-V354 WeakPolarHBondContact O-CG2 3.48Å; F350-V354 PolarHBondContact O-N 2.94Å
351W89.3Confident88.2Confident200 Ų20080.9 Ų80.976%0.75842%0.417SS*.Hα-helixtrans-69.7-36.7-179.6-67110.1000112.9S349 G353 V354 L355S349-W351 PolarHBondContact O-N 3Å; W351-G353 VanDerWaalsContact C-N 3.33Å; W351-V354 PolarHBondContact O-N 3.12Å; W351-L355 PolarHBondContact O-N 3.43Å
352T87.6Confident88.1Confident16 Ų1680.9 Ų80.910%0.09842%0.416CS..Hα-helixtrans-72.1-28.8174.458.10000111.9V343 H344 D347 S349 L355 L356V343-T352 HydrophobicContact CG1-CG2 3.94Å; H344-T352 PolarHBondContact ND1-OG1 2.94Å; D347-T352 WeakPolarHBondContact O-CG2 3.2Å; D347-T352 PolarHBondContact O-OG1 3.08Å; S349-T352 PolarHBondContact N-OG1 3.19Å; S349-T352 PolarHBondContact O-N 3.29Å; S349-T352 PolarHBondContact O-OG1 3.12Å; S349-T352 VanDerWaalsContact O-OG1 3.06Å; S349-T352 WeakPolarHBondContact OG-CG2 3.48Å; S349-T352 PolarHBondContact OG-N 3.41Å; S349-T352 PolarHBondContact OG-OG1 2.87Å; S349-T352 VanDerWaalsContact OG-OG1 3.12Å; T352-L355 WeakPolarHBondContact O-CB 3.29Å; T352-L355 PolarHBondContact O-N 3.44Å; T352-L356 PolarHBondContact O-N 3.17Å
353G85.6Confident87.9Confident20 Ų2079.7 Ų79.721%0.20641%0.405CS..Hα-helixtrans-65.7-38.7169.100000113.2H344 S349 F350 W351 L355 L356 Y357H344-G353 PolarHBondContact ND1-N 3.2Å; S349-G353 PolarHBondContact O-N 3.32Å; F350-G353 PolarHBondContact O-N 2.78Å; W351-G353 VanDerWaalsContact C-N 3.33Å; G353-L355 VanDerWaalsContact C-N 3.34Å; G353-L356 PolarHBondContact O-N 3.38Å; G353-Y357 WeakPolarHBondContact O-CD2 3.31Å
354V87.4Confident87.4Confident61 Ų6180.2 Ų80.237%0.3741%0.413SS..Hα-helixtrans-66.3-37.4172.8173.70000111.3F350 W351 L356 Y357F350-V354 HydrophobicContact CD1-CG2 4.5Å; F350-V354 HydrophobicContact CE1-CG2 4.04Å; F350-V354 HydrophobicContact CZ-CG2 4.12Å; F350-V354 WeakPolarHBondContact O-CG2 3.48Å; F350-V354 PolarHBondContact O-N 2.94Å; W351-V354 PolarHBondContact O-N 3.12Å; V354-L356 PolarHBondContact O-N 3.48Å; V354-Y357 PolarHBondContact O-N 2.93Å
355L88.8Confident87.1Confident34 Ų3482.1 Ų82.118%0.17843%0.428CS..Hα-helixtrans-57.7-33179.3-178.262.9000112.8W339 A340 V343 W351 T352 G353 Y357 I358 P359W339-L355 HydrophobicContact CH2-CD2 4.35Å; W339-L355 HydrophobicContact CZ3-CD1 4.18Å; W339-L355 HydrophobicContact CZ3-CD2 4.33Å; A340-L355 HydrophobicContact CB-CG 4.17Å; V343-L355 HydrophobicContact CB-CD2 4.19Å; V343-L355 HydrophobicContact CG1-CD2 3.92Å; W351-L355 PolarHBondContact O-N 3.43Å; T352-L355 WeakPolarHBondContact O-CB 3.29Å; T352-L355 PolarHBondContact O-N 3.44Å; G353-L355 VanDerWaalsContact C-N 3.34Å; L355-Y357 PolarHBondContact O-N 3.24Å; L355-I358 HydrophobicContact CD1-CD1 4.05Å; L355-I358 PolarHBondContact O-N 3.12Å; L355-I358 VanDerWaalsContact O-N 3.12Å; L355-P359 WeakPolarHBondContact O-CD 3.41Å
356L85.1Confident87Confident47 Ų4778.5 Ų78.525%0.24641%0.411CS..THydrogen-bonded Turntrans-58.6-31.6178.5-65.2177.4000113.4A340 L341 H344 T352 G353 V354A340-L356 HydrophobicContact CB-CD2 4.41Å; L341-L356 HydrophobicContact CB-CD2 4.48Å; L341-L356 HydrophobicContact CD2-CD2 3.69Å; L341-L356 HydrophobicContact CG-CD2 4Å; H344-L356 HydrophobicContact CB-CD1 4.36Å; H344-L356 HydrophobicContact CB-CD2 3.91Å; H344-L356 HydrophobicContact CB-CG 4.24Å; T352-L356 PolarHBondContact O-N 3.17Å; G353-L356 PolarHBondContact O-N 3.38Å; V354-L356 PolarHBondContact O-N 3.48Å
357Y83.1Confident86.8Confident164 Ų16472.9 Ų72.964%0.64339%0.385SS*.THydrogen-bonded Turntrans-84.4-17.8-179.8-61.1-77.5000113.3G353 V354 L355 S360 I361G353-Y357 WeakPolarHBondContact O-CD2 3.31Å; V354-Y357 PolarHBondContact O-N 2.93Å; L355-Y357 PolarHBondContact O-N 3.24Å; Y357-S360 PolarHBondContact O-N 3.2Å; Y357-I361 VanDerWaalsContact O-CG1 3.32Å; Y357-I361 WeakPolarHBondContact O-CG1 3.28Å; Y357-I361 PolarHBondContact O-N 2.78Å; Y357-I361 VanDerWaalsContact O-N 3.15Å
358I85.2Confident86.5Confident74 Ų7473.5 Ų73.538%0.37938%0.384SS..Hα-helixtrans-64.4-48.7-173.4-65.9-179.4000112.2L355 S360 I361 I362L355-I358 HydrophobicContact CD1-CD1 4.05Å; L355-I358 PolarHBondContact O-N 3.12Å; L355-I358 VanDerWaalsContact O-N 3.12Å; I358-S360 VanDerWaalsContact C-N 3.31Å; I358-S360 PolarHBondContact O-N 2.86Å; I358-I361 PolarHBondContact O-N 3.35Å; I358-I362 HydrophobicContact CG2-CD1 3.6Å; I358-I362 HydrophobicContact CG2-CG1 4.22Å; I358-I362 WeakPolarHBondContact O-CG1 3.48Å; I358-I362 PolarHBondContact O-N 2.85Å
359P88Confident86.5Confident6 Ų672.5 Ų72.54%0.03938%0.376CS..Hα-helixtrans-55.7-43.4178.1-27.735.5000113.2Y333 M336 E337 A340 L355 I362 Y363Y333-P359 HydrophobicContact CD2-CB 4.46Å; Y333-P359 HydrophobicContact CE2-CB 4.4Å; M336-P359 HydrophobicContact CB-CB 4.1Å; M336-P359 HydrophobicContact CB-CG 4.31Å; E337-P359 HydrophobicContact CB-CB 4.49Å; A340-P359 HydrophobicContact CB-CG 3.91Å; L355-P359 WeakPolarHBondContact O-CD 3.41Å; P359-I362 PolarHBondContact O-N 3.28Å; P359-Y363 VanDerWaalsContact O-CB 3.32Å; P359-Y363 WeakPolarHBondContact O-CB 3.4Å; P359-Y363 PolarHBondContact O-N 3.5Å
360S83.6Confident86.4Confident46 Ų4671.8 Ų71.832%0.32237%0.367SS..Hα-helixtrans-67.1-39.7-179.8-45.70000112.2Y357 I358 Y363 A364Y357-S360 PolarHBondContact O-N 3.2Å; I358-S360 VanDerWaalsContact C-N 3.31Å; I358-S360 PolarHBondContact O-N 2.86Å; S360-Y363 PolarHBondContact O-N 3.01Å; S360-A364 WeakPolarHBondContact O-CB 3.43Å; S360-A364 PolarHBondContact O-N 3.24Å
361I83.1Confident86.4Confident108 Ų10865.4 Ų65.455%0.55434%0.34SS*.Hα-helixtrans-64.6-45.3174.7-66.4166.2000110.7Y357 I358 Y363 A364 V365Y357-I361 VanDerWaalsContact O-CG1 3.32Å; Y357-I361 WeakPolarHBondContact O-CG1 3.28Å; Y357-I361 PolarHBondContact O-N 2.78Å; Y357-I361 VanDerWaalsContact O-N 3.15Å; I358-I361 PolarHBondContact O-N 3.35Å; I361-Y363 VanDerWaalsContact C-N 3.34Å; I361-Y363 PolarHBondContact O-N 3.44Å; I361-A364 PolarHBondContact O-N 3.23Å; I361-V365 WeakPolarHBondContact O-CG2 3.19Å; I361-V365 PolarHBondContact O-N 2.8Å; I361-V365 VanDerWaalsContact O-N 3.12Å
362I86.8Confident86.4Confident80 Ų8061.9 Ų61.941%0.4134%0.335SS..Hα-helixtrans-60.3-46.9177.2-68.9171.3000110I358 P359 A364 V365 V366I358-I362 HydrophobicContact CG2-CD1 3.6Å; I358-I362 HydrophobicContact CG2-CG1 4.22Å; I358-I362 WeakPolarHBondContact O-CG1 3.48Å; I358-I362 PolarHBondContact O-N 2.85Å; P359-I362 PolarHBondContact O-N 3.28Å; I362-A364 PolarHBondContact O-N 3.07Å; I362-V365 PolarHBondContact O-N 3.45Å; I362-V366 HydrophobicContact CG2-CG2 4.28Å; I362-V366 WeakPolarHBondContact O-CG2 3.17Å; I362-V366 PolarHBondContact O-N 3.09Å
363Y86.3Confident86.7Confident21 Ų2165.5 Ų65.58%0.08236%0.357CS..Hα-helixtrans-61.2-44.4-179.8-177.8-125.1000111.9V329 Y333 P359 S360 I361 V365 V366 I367V329-Y363 HydrophobicContact CG1-CE2 4.35Å; Y333-Y363 AromaticContact CD1-CD1 3.99Å; Y333-Y363 HydrophobicContact CD1-CD1 3.99Å; Y333-Y363 HydrophobicContact CD1-CE1 4.09Å; Y333-Y363 HydrophobicContact CD1-CG 4.28Å; Y333-Y363 VanDerWaalsContact CD2-CB 3.42Å; Y333-Y363 AromaticContact CD2-CD1 3.84Å; Y333-Y363 HydrophobicContact CD2-CD1 3.84Å; Y333-Y363 HydrophobicContact CD2-CD2 4.29Å; Y333-Y363 AromaticContact CD2-CG 3.6Å; Y333-Y363 HydrophobicContact CD2-CG 3.6Å; Y333-Y363 HydrophobicContact CE1-CD1 4.26Å; Y333-Y363 HydrophobicContact CE1-CE1 4.44Å; Y333-Y363 HydrophobicContact CE2-CD1 4.09Å; Y333-Y363 HydrophobicContact CE2-CG 4.24Å; Y333-Y363 AromaticContact CG-CD1 3.77Å; Y333-Y363 HydrophobicContact CG-CD1 3.77Å; Y333-Y363 AromaticContact CG-CD2 3.91Å; Y333-Y363 HydrophobicContact CG-CD2 3.91Å; Y333-Y363 HydrophobicContact CG-CE1 4.24Å; Y333-Y363 HydrophobicContact CG-CE2 4.37Å; Y333-Y363 AromaticContact CG-CG 3.6Å; Y333-Y363 HydrophobicContact CG-CG 3.6Å; P359-Y363 VanDerWaalsContact O-CB 3.32Å; P359-Y363 WeakPolarHBondContact O-CB 3.4Å; P359-Y363 PolarHBondContact O-N 3.5Å; S360-Y363 PolarHBondContact O-N 3.01Å; I361-Y363 VanDerWaalsContact C-N 3.34Å; I361-Y363 PolarHBondContact O-N 3.44Å; Y363-V365 VanDerWaalsContact C-N 3.33Å; Y363-V365 PolarHBondContact O-N 2.79Å; Y363-V366 PolarHBondContact O-N 2.96Å; Y363-V366 VanDerWaalsContact O-N 3.17Å; Y363-I367 HydrophobicContact CD1-CD1 3.9Å; Y363-I367 HydrophobicContact CD2-CD1 4.34Å; Y363-I367 HydrophobicContact CD2-CG1 4.3Å; Y363-I367 HydrophobicContact CE1-CD1 3.49Å; Y363-I367 VanDerWaalsContact CE1-CD1 3.49Å; Y363-I367 HydrophobicContact CE1-CG1 4.38Å; Y363-I367 HydrophobicContact CE2-CD1 3.98Å; Y363-I367 HydrophobicContact CE2-CG1 3.97Å; Y363-I367 HydrophobicContact CG-CD1 4.29Å; Y363-I367 WeakPolarHBondContact O-CG1 3.36Å; Y363-I367 PolarHBondContact O-N 2.82Å
364A82.2Confident87.2Confident52 Ų5265 Ų6543%0.4335%0.349SS..Hα-helixtrans-57.5-44.3175.100000112.3S360 I361 I362 I367 E368S360-A364 WeakPolarHBondContact O-CB 3.43Å; S360-A364 PolarHBondContact O-N 3.24Å; I361-A364 PolarHBondContact O-N 3.23Å; I362-A364 PolarHBondContact O-N 3.07Å; A364-I367 PolarHBondContact O-N 3.07Å; A364-E368 PolarHBondContact O-N 3.41Å
365V84.7Confident87.4Confident89 Ų8964.7 Ų64.754%0.53934%0.341SS..Hα-helixtrans-65.1-41176.71740000111.6I361 I362 Y363 E368 V369I361-V365 WeakPolarHBondContact O-CG2 3.19Å; I361-V365 PolarHBondContact O-N 2.8Å; I361-V365 VanDerWaalsContact O-N 3.12Å; I362-V365 PolarHBondContact O-N 3.45Å; Y363-V365 VanDerWaalsContact C-N 3.33Å; Y363-V365 PolarHBondContact O-N 2.79Å; V365-E368 PolarHBondContact O-N 2.91Å; V365-V369 WeakPolarHBondContact O-CG2 3.31Å; V365-V369 PolarHBondContact O-N 3.46Å; V365-V369 VanDerWaalsContact O-N 3.14Å
366V89.3Confident87.6Confident52 Ų5271.2 Ų71.232%0.31537%0.365SS..Hα-helixtrans-64.2-41.6178.8171.80000111.2V329 I362 Y363 E368 V369 M370V329-V366 HydrophobicContact CG1-CG1 3.82Å; I362-V366 HydrophobicContact CG2-CG2 4.28Å; I362-V366 WeakPolarHBondContact O-CG2 3.17Å; I362-V366 PolarHBondContact O-N 3.09Å; Y363-V366 PolarHBondContact O-N 2.96Å; Y363-V366 VanDerWaalsContact O-N 3.17Å; V366-E368 PolarHBondContact O-N 3.33Å; V366-V369 PolarHBondContact O-N 2.97Å; V366-M370 HydrophobicContact CG1-CG 4.16Å; V366-M370 HydrophobicContact CG1-SD 3.86Å; V366-M370 WeakPolarHBondContact O-CB 3.48Å; V366-M370 VanDerWaalsContact O-CG 3.29Å; V366-M370 WeakPolarHBondContact O-CG 3.24Å; V366-M370 PolarHBondContact O-N 3.4Å
367I86.9Confident88.1Confident26 Ų2670.1 Ų70.113%0.13336%0.363CS..Hα-helixtrans-58-48.6176.8-69.4169.9000110.9Y363 A364 V369 M370 N371 N408Y363-I367 HydrophobicContact CD1-CD1 3.9Å; Y363-I367 HydrophobicContact CD2-CD1 4.34Å; Y363-I367 HydrophobicContact CD2-CG1 4.3Å; Y363-I367 HydrophobicContact CE1-CD1 3.49Å; Y363-I367 VanDerWaalsContact CE1-CD1 3.49Å; Y363-I367 HydrophobicContact CE1-CG1 4.38Å; Y363-I367 HydrophobicContact CE2-CD1 3.98Å; Y363-I367 HydrophobicContact CE2-CG1 3.97Å; Y363-I367 HydrophobicContact CG-CD1 4.29Å; Y363-I367 WeakPolarHBondContact O-CG1 3.36Å; Y363-I367 PolarHBondContact O-N 2.82Å; A364-I367 PolarHBondContact O-N 3.07Å; I367-V369 VanDerWaalsContact C-N 3.34Å; I367-V369 PolarHBondContact O-N 3.2Å; I367-M370 PolarHBondContact O-N 2.87Å; I367-M370 VanDerWaalsContact O-N 3.17Å; I367-N371 WeakPolarHBondContact O-CB 3.3Å; I367-N371 VanDerWaalsContact O-CG 3.22Å; I367-N371 PolarHBondContact O-N 2.56Å; I367-N371 PolarHBondContact O-OD1 2.86Å; I367-N408 HydrophobicContact CG2-CB 4.23Å
368E83.3Confident88.7Confident130 Ų13062.3 Ų62.361%0.60733%0.332SS*.Hα-helixtrans-60.5-43.1179.5-71.9-56139.100112.3A364 V365 V366 M370 N371 L372A364-E368 PolarHBondContact O-N 3.41Å; V365-E368 PolarHBondContact O-N 2.91Å; V366-E368 PolarHBondContact O-N 3.33Å; E368-M370 PolarHBondContact O-N 3.5Å; E368-N371 PolarHBondContact O-N 2.82Å; E368-L372 PolarHBondContact O-N 2.78Å; E368-L372 VanDerWaalsContact O-N 3.07Å
369V88.4Confident89.1Confident83 Ų8362 Ų6250%0.50333%0.329SS..Hα-helixtrans-63.5-42.8175.7173.50000111V365 V366 I367 L372 V373V365-V369 WeakPolarHBondContact O-CG2 3.31Å; V365-V369 PolarHBondContact O-N 3.46Å; V365-V369 VanDerWaalsContact O-N 3.14Å; V366-V369 PolarHBondContact O-N 2.97Å; I367-V369 VanDerWaalsContact C-N 3.34Å; I367-V369 PolarHBondContact O-N 3.2Å; V369-L372 PolarHBondContact O-N 2.89Å; V369-V373 HydrophobicContact CG1-CG2 4.4Å; V369-V373 VanDerWaalsContact O-CG2 3.31Å; V369-V373 WeakPolarHBondContact O-CG2 3.26Å; V369-V373 PolarHBondContact O-N 2.95Å
370M91.2Very high89.5Confident40 Ų4068.3 Ų68.320%0.19736%0.356CS..Hα-helixtrans-63.6-43.5177.9-75.9-17663.700112.1V329 V366 I367 E368 L372 V373 Y374 F404V329-M370 HydrophobicContact CB-SD 4.3Å; V329-M370 HydrophobicContact CG1-SD 4.14Å; V329-M370 HydrophobicContact CG2-CE 4.48Å; V329-M370 HydrophobicContact CG2-SD 4.05Å; V366-M370 HydrophobicContact CG1-CG 4.16Å; V366-M370 HydrophobicContact CG1-SD 3.86Å; V366-M370 WeakPolarHBondContact O-CB 3.48Å; V366-M370 VanDerWaalsContact O-CG 3.29Å; V366-M370 WeakPolarHBondContact O-CG 3.24Å; V366-M370 PolarHBondContact O-N 3.4Å; I367-M370 PolarHBondContact O-N 2.87Å; I367-M370 VanDerWaalsContact O-N 3.17Å; E368-M370 PolarHBondContact O-N 3.5Å; M370-L372 VanDerWaalsContact C-N 3.34Å; M370-L372 PolarHBondContact O-N 3.16Å; M370-V373 PolarHBondContact O-N 3.06Å; M370-Y374 VanDerWaalsContact O-CB 3.23Å; M370-Y374 WeakPolarHBondContact O-CB 3.38Å; M370-Y374 PolarHBondContact O-N 3.17Å; M370-F404 HydrophobicContact CB-CE1 4.43Å; M370-F404 HydrophobicContact CB-CZ 4.19Å; M370-F404 HydrophobicContact CE-CE2 4.48Å; M370-F404 HydrophobicContact CE-CZ 4Å
371N89.6Confident90.1Very high25 Ų2566.8 Ų66.813%0.13434%0.344CS..Hα-helixtrans-58.9-45.4176.1-69.6-12.9000111.1I367 E368 R375 N405 N408I367-N371 WeakPolarHBondContact O-CB 3.3Å; I367-N371 VanDerWaalsContact O-CG 3.22Å; I367-N371 PolarHBondContact O-N 2.56Å; I367-N371 PolarHBondContact O-OD1 2.86Å; E368-N371 PolarHBondContact O-N 2.82Å; N371-R375 WeakPolarHBondContact O-CB 3.44Å; N371-R375 PolarHBondContact O-N 3.45Å; N371-N405 PolarHBondContact OD1-OD1 3.05Å; N371-N408 PolarHBondContact OD1-ND2 2.9Å
372L88.7Confident90.6Very high125 Ų12561.6 Ų61.665%0.65432%0.318SS*.Hα-helixtrans-63.1-49.1178-17865.9000112.3E368 V369 M370 Y374 R375 Y376E368-L372 PolarHBondContact O-N 2.78Å; E368-L372 VanDerWaalsContact O-N 3.07Å; V369-L372 PolarHBondContact O-N 2.89Å; M370-L372 VanDerWaalsContact C-N 3.34Å; M370-L372 PolarHBondContact O-N 3.16Å; L372-Y374 VanDerWaalsContact C-N 3.34Å; L372-Y374 PolarHBondContact O-N 3.06Å; L372-R375 PolarHBondContact O-N 3.32Å; L372-Y376 PolarHBondContact O-N 3.43Å
373V93.9Very high90.9Very high93 Ų9360.3 Ų60.356%0.56431%0.31SS*.Hα-helixtrans-63.2-43180171.60000110.8V369 M370 Y376 A377V369-V373 HydrophobicContact CG1-CG2 4.4Å; V369-V373 VanDerWaalsContact O-CG2 3.31Å; V369-V373 WeakPolarHBondContact O-CG2 3.26Å; V369-V373 PolarHBondContact O-N 2.95Å; M370-V373 PolarHBondContact O-N 3.06Å; V373-Y376 PolarHBondContact O-N 3.03Å; V373-A377 PolarHBondContact O-N 3.07Å; V373-A377 VanDerWaalsContact O-N 3.13Å
374Y95.4Very high91.3Very high8 Ų864 Ų643%0.03132%0.324CS..Hα-helixtrans-66.1-39179.1-178.5-92.4000112.2F318 V319 C322 M370 L372 Y376 A377 A378 K400 V401 F404F318-Y374 HydrophobicContact CE1-CE2 4.37Å; V319-Y374 WeakPolarHBondContact CG2-OH 3.17Å; C322-Y374 HydrophobicContact CB-CD2 3.83Å; C322-Y374 HydrophobicContact CB-CE2 3.67Å; M370-Y374 VanDerWaalsContact O-CB 3.23Å; M370-Y374 WeakPolarHBondContact O-CB 3.38Å; M370-Y374 PolarHBondContact O-N 3.17Å; L372-Y374 VanDerWaalsContact C-N 3.34Å; L372-Y374 PolarHBondContact O-N 3.06Å; Y374-Y376 VanDerWaalsContact C-N 3.35Å; Y374-Y376 PolarHBondContact O-N 3.34Å; Y374-A377 PolarHBondContact O-N 3.42Å; Y374-A378 HydrophobicContact CD1-CB 4.41Å; Y374-A378 HydrophobicContact CE1-CB 4.09Å; Y374-A378 WeakPolarHBondContact O-CB 3.49Å; Y374-A378 PolarHBondContact O-N 3.11Å; Y374-K400 VanDerWaalsContact CE1-O 3.23Å; Y374-K400 WeakPolarHBondContact CE1-O 3.39Å; Y374-K400 PolarHBondContact OH-O 2.94Å; Y374-V401 HydrophobicContact CE1-CG2 4.45Å; Y374-F404 HydrophobicContact CD1-CB 3.59Å; Y374-F404 AromaticContact CD1-CD1 3.43Å; Y374-F404 HydrophobicContact CD1-CD1 3.43Å; Y374-F404 VanDerWaalsContact CD1-CD1 3.43Å; Y374-F404 HydrophobicContact CD1-CD2 4.25Å; Y374-F404 HydrophobicContact CD1-CE1 4.1Å; Y374-F404 AromaticContact CD1-CG 3.49Å; Y374-F404 HydrophobicContact CD1-CG 3.49Å; Y374-F404 VanDerWaalsContact CD1-CG 3.49Å; Y374-F404 HydrophobicContact CD2-CB 4.42Å; Y374-F404 HydrophobicContact CD2-CD1 4.17Å; Y374-F404 AromaticContact CD2-CD2 3.74Å; Y374-F404 HydrophobicContact CD2-CD2 3.74Å; Y374-F404 HydrophobicContact CD2-CE1 4.31Å; Y374-F404 AromaticContact CD2-CE2 3.95Å; Y374-F404 HydrophobicContact CD2-CE2 3.95Å; Y374-F404 AromaticContact CD2-CG 3.85Å; Y374-F404 HydrophobicContact CD2-CG 3.85Å; Y374-F404 HydrophobicContact CD2-CZ 4.22Å; Y374-F404 HydrophobicContact CE1-CB 3.28Å; Y374-F404 HydrophobicContact CE1-CD1 4.09Å; Y374-F404 HydrophobicContact CE1-CD2 4.38Å; Y374-F404 AromaticContact CE1-CG 3.69Å; Y374-F404 HydrophobicContact CE1-CG 3.69Å; Y374-F404 HydrophobicContact CE2-CB 4.16Å; Y374-F404 AromaticContact CE2-CD2 3.88Å; Y374-F404 HydrophobicContact CE2-CD2 3.88Å; Y374-F404 HydrophobicContact CE2-CE2 4.46Å; Y374-F404 HydrophobicContact CE2-CG 4.02Å; Y374-F404 HydrophobicContact CG-CB 4.14Å; Y374-F404 AromaticContact CG-CD1 3.46Å; Y374-F404 HydrophobicContact CG-CD1 3.46Å; Y374-F404 VanDerWaalsContact CG-CD1 3.46Å; Y374-F404 AromaticContact CG-CD2 3.91Å; Y374-F404 HydrophobicContact CG-CD2 3.91Å; Y374-F404 AromaticContact CG-CE1 3.67Å; Y374-F404 HydrophobicContact CG-CE1 3.67Å; Y374-F404 HydrophobicContact CG-CE2 4.14Å; Y374-F404 AromaticContact CG-CG 3.56Å; Y374-F404 HydrophobicContact CG-CG 3.56Å; Y374-F404 HydrophobicContact CG-CZ 4.01Å; Y374-F404 AromaticContact CZ-CG 3.91Å
375R91.7Very high91.9Very high55 Ų5561.5 Ų61.521%0.20830%0.303CS..Hα-helixtrans-57.2-47.9175.4-177.4175.1-178.9167.77.9111.5N371 L372 A377 A378 E379 D495N371-R375 WeakPolarHBondContact O-CB 3.44Å; N371-R375 PolarHBondContact O-N 3.45Å; L372-R375 PolarHBondContact O-N 3.32Å; R375-A377 VanDerWaalsContact C-N 3.32Å; R375-A377 PolarHBondContact O-N 2.85Å; R375-A378 PolarHBondContact O-N 3.37Å; R375-E379 IonicContact NE-OE1 2.84Å; R375-E379 PolarHBondContact NE-OE1 3.21Å; R375-E379 WeakPolarHBondContact O-CG 3.41Å; R375-E379 PolarHBondContact O-N 2.92Å; R375-D495 IonicContact CZ-OD1 2.96Å; R375-D495 IonicContact CZ-OD2 3.88Å; R375-D495 IonicContact NH1-OD1 2.74Å; R375-D495 PolarHBondContact NH1-OD1 3.13Å; R375-D495 IonicContact NH1-OD2 2.96Å; R375-D495 PolarHBondContact NH1-OD2 3.31Å; R375-D495 IonicContact NH2-OD1 3.98Å; R375-D495 IonicContact NH2-OD2 2.93Å; R375-D495 PolarHBondContact NH2-OD2 3.03Å
376Y93.7Very high92.4Very high171 Ų17157.3 Ų57.367%0.67128%0.278SS*.Hα-helixtrans-59.8-43176.8-177.1-97.9000112.1L372 V373 Y374 F380L372-Y376 PolarHBondContact O-N 3.43Å; V373-Y376 PolarHBondContact O-N 3.03Å; Y374-Y376 VanDerWaalsContact C-N 3.35Å; Y374-Y376 PolarHBondContact O-N 3.34Å; Y376-F380 WeakPolarHBondContact O-CB 3.3Å; Y376-F380 PolarHBondContact O-N 2.9Å; Y376-F380 VanDerWaalsContact O-N 3.08Å
377A95.8Very high92.6Very high24 Ų2454.9 Ų54.920%0.19826%0.263CS..Hα-helixtrans-64.6-41.5176.500000112.4F318 V373 Y374 R375 F380 L381F318-A377 HydrophobicContact CE1-CB 3.97Å; F318-A377 HydrophobicContact CZ-CB 3.79Å; V373-A377 PolarHBondContact O-N 3.07Å; V373-A377 VanDerWaalsContact O-N 3.13Å; Y374-A377 PolarHBondContact O-N 3.42Å; R375-A377 VanDerWaalsContact C-N 3.32Å; R375-A377 PolarHBondContact O-N 2.85Å; A377-F380 PolarHBondContact O-N 2.71Å; A377-L381 WeakPolarHBondContact O-CB 3.21Å; A377-L381 PolarHBondContact O-N 3Å
378A95.8Very high92.7Very high1 Ų156 Ų561%0.00827%0.266CS..Hα-helixtrans-66.4-39.917900000112.2Y374 R375 T382 L397 K400 V401Y374-A378 HydrophobicContact CD1-CB 4.41Å; Y374-A378 HydrophobicContact CE1-CB 4.09Å; Y374-A378 WeakPolarHBondContact O-CB 3.49Å; Y374-A378 PolarHBondContact O-N 3.11Å; R375-A378 PolarHBondContact O-N 3.37Å; A378-T382 VanDerWaalsContact O-CB 3.29Å; A378-T382 WeakPolarHBondContact O-CB 3.41Å; A378-T382 PolarHBondContact O-N 3.38Å; A378-T382 PolarHBondContact O-OG1 3.41Å; A378-L397 HydrophobicContact CB-CD1 3.95Å; A378-K400 HydrophobicContact CB-CB 4.25Å; A378-K400 HydrophobicContact CB-CD 4.46Å; A378-V401 HydrophobicContact CB-CG2 3.79Å
379E93.4Very high93Very high68 Ų6851.3 Ų51.332%0.31825%0.245SC..Hα-helixtrans-61.9-49.7173.5-74.8175.2-16900111.1R375 L381 T382 E383 L397R375-E379 IonicContact NE-OE1 2.84Å; R375-E379 PolarHBondContact NE-OE1 3.21Å; R375-E379 WeakPolarHBondContact O-CG 3.41Å; R375-E379 PolarHBondContact O-N 2.92Å; E379-L381 VanDerWaalsContact C-N 3.35Å; E379-L381 PolarHBondContact O-N 3.43Å; E379-T382 PolarHBondContact O-N 3.09Å; E379-E383 WeakPolarHBondContact O-CB 3.13Å; E379-E383 PolarHBondContact O-N 3.39Å; E379-L397 HydrophobicContact CB-CD1 4.45Å; E379-L397 HydrophobicContact CG-CD1 3.84Å; E379-L397 HydrophobicContact CG-CD2 3.93Å
380F94.8Very high92.8Very high138 Ų13851.3 Ų51.361%0.60524%0.239SC*.Hα-helixtrans-58-46.9177.3174.8-97.8000112.2Y376 A377 E383 W384Y376-F380 WeakPolarHBondContact O-CB 3.3Å; Y376-F380 PolarHBondContact O-N 2.9Å; Y376-F380 VanDerWaalsContact O-N 3.08Å; A377-F380 PolarHBondContact O-N 2.71Å; F380-E383 PolarHBondContact O-N 2.84Å; F380-W384 WeakPolarHBondContact O-CB 3.43Å; F380-W384 PolarHBondContact O-N 3.31Å
381L96.1Very high92.5Very high13 Ų1351.2 Ų51.27%0.06824%0.242CC..Hα-helixtrans-65.6-41.3-179.2-17759000111.8V314 S315 F318 A377 E379 W384 E385V314-L381 HydrophobicContact CG1-CD1 4.31Å; S315-L381 VanDerWaalsContact OG-CD2 3.3Å; S315-L381 WeakPolarHBondContact OG-CD2 3.38Å; S315-L381 WeakPolarHBondContact OG-CG 3.22Å; F318-L381 HydrophobicContact CB-CD2 4.37Å; F318-L381 HydrophobicContact CD1-CD2 3.64Å; F318-L381 HydrophobicContact CE1-CD2 4.33Å; F318-L381 HydrophobicContact CG-CD2 4.25Å; A377-L381 WeakPolarHBondContact O-CB 3.21Å; A377-L381 PolarHBondContact O-N 3Å; E379-L381 VanDerWaalsContact C-N 3.35Å; E379-L381 PolarHBondContact O-N 3.43Å; L381-W384 HydrophobicContact CD1-CE3 4.31Å; L381-W384 WeakPolarHBondContact O-CB 3.43Å; L381-W384 PolarHBondContact O-N 2.84Å; L381-E385 WeakPolarHBondContact O-CG 3.41Å; L381-E385 PolarHBondContact O-N 3.43Å
382T95.6Very high92.5Very high0 Ų051.7 Ų51.70%025%0.248CC..Hα-helixtrans-71.8-33.5179.1-50.20000111.7A378 E379 W384 E385 Y393 H396 L397 K400A378-T382 VanDerWaalsContact O-CB 3.29Å; A378-T382 WeakPolarHBondContact O-CB 3.41Å; A378-T382 PolarHBondContact O-N 3.38Å; A378-T382 PolarHBondContact O-OG1 3.41Å; E379-T382 PolarHBondContact O-N 3.09Å; T382-W384 VanDerWaalsContact C-N 3.32Å; T382-E385 WeakPolarHBondContact O-CB 3.24Å; T382-E385 PolarHBondContact O-N 2.83Å; T382-Y393 HydrophobicContact CG2-CD2 3.62Å; T382-Y393 HydrophobicContact CG2-CE2 3.71Å; T382-Y393 HydrophobicContact CG2-CG 4.36Å; T382-H396 HydrophobicContact CG2-CB 4.07Å; T382-L397 HydrophobicContact CG2-CB 4.17Å; T382-K400 PolarHBondContact OG1-NZ 3.42Å
383E93.1Very high92.6Very high52 Ų5246.9 Ų46.924%0.24322%0.221CC..Hα-helixtrans-64.2-40.9170.9-173.969-160.700110.2R156 R282 E379 F380 E385 N386 Y393R156-E383 IonicContact CZ-OE1 3.14Å; R156-E383 IonicContact NH2-OE1 3.34Å; R156-E383 PolarHBondContact NH2-OE1 3.34Å; R156-E383 IonicContact NH2-OE2 3.04Å; R282-E383 IonicContact CZ-OE1 3.46Å; R282-E383 IonicContact CZ-OE2 3.72Å; R282-E383 VanDerWaalsContact CZ-OE2 3.27Å; R282-E383 IonicContact NH1-OE1 3.28Å; R282-E383 IonicContact NH1-OE2 3.3Å; R282-E383 PolarHBondContact NH1-OE2 2.84Å; R282-E383 IonicContact NH2-OE1 2.78Å; R282-E383 PolarHBondContact NH2-OE1 2.84Å; R282-E383 IonicContact NH2-OE2 3.33Å; R282-E383 PolarHBondContact NH2-OE2 2.88Å; E379-E383 WeakPolarHBondContact O-CB 3.13Å; E379-E383 PolarHBondContact O-N 3.39Å; F380-E383 PolarHBondContact O-N 2.84Å; E383-E385 VanDerWaalsContact C-N 3.33Å; E383-E385 PolarHBondContact O-N 3.42Å; E383-N386 PolarHBondContact O-N 2.89Å; E383-N386 VanDerWaalsContact O-N 3.17Å; E383-Y393 HydrophobicContact CB-CE2 4.41Å
384W94Very high92.3Very high99 Ų9945.8 Ų45.838%0.37521%0.21SC..Hα-helixtrans-67.4-27.9176.7-17784.9000113.9R310 V314 F380 L381 T382 N386R310-W384 HydrophobicContact CB-CE3 4.06Å; R310-W384 HydrophobicContact CB-CH2 3.84Å; R310-W384 HydrophobicContact CB-CZ3 3.38Å; R310-W384 HydrophobicContact CG-CE3 4.16Å; R310-W384 HydrophobicContact CG-CH2 3.4Å; R310-W384 HydrophobicContact CG-CZ2 4.04Å; R310-W384 HydrophobicContact CG-CZ3 3.47Å; R310-W384 VanDerWaalsContact CG-CZ3 3.47Å; R310-W384 PolarHBondContact NH1-O 2.97Å; V314-W384 HydrophobicContact CB-CH2 4.25Å; V314-W384 HydrophobicContact CB-CZ3 3.98Å; V314-W384 HydrophobicContact CG1-CH2 4.4Å; V314-W384 HydrophobicContact CG1-CZ3 4.12Å; V314-W384 HydrophobicContact CG2-CH2 3.94Å; V314-W384 HydrophobicContact CG2-CZ3 4.18Å; F380-W384 WeakPolarHBondContact O-CB 3.43Å; F380-W384 PolarHBondContact O-N 3.31Å; L381-W384 HydrophobicContact CD1-CE3 4.31Å; L381-W384 WeakPolarHBondContact O-CB 3.43Å; L381-W384 PolarHBondContact O-N 2.84Å; T382-W384 VanDerWaalsContact C-N 3.32Å; W384-N386 PolarHBondContact O-N 3.36Å
385E95.1Very high92.1Very high0 Ų047.9 Ų47.90%022%0.222CC..Hα-helixtrans-63.6-20.3172.9-72.8165.2-167.800112.9R307 I311 S315 L381 T382 E383 H387 K400R307-E385 WeakPolarHBondContact CG-O 2.97Å; I311-E385 HydrophobicContact CG1-CB 4.39Å; I311-E385 HydrophobicContact CG1-CG 3.82Å; S315-E385 WeakPolarHBondContact CB-OE1 3.21Å; S315-E385 PolarHBondContact OG-OE1 3.35Å; L381-E385 WeakPolarHBondContact O-CG 3.41Å; L381-E385 PolarHBondContact O-N 3.43Å; T382-E385 WeakPolarHBondContact O-CB 3.24Å; T382-E385 PolarHBondContact O-N 2.83Å; E383-E385 VanDerWaalsContact C-N 3.33Å; E383-E385 PolarHBondContact O-N 3.42Å; E385-H387 IonicContact OE2-CD2 3.33Å; E385-H387 IonicContact OE2-CE1 3.76Å; E385-H387 IonicContact OE2-NE2 2.62Å; E385-H387 PolarHBondContact OE2-NE2 3.44Å; E385-K400 VanDerWaalsContact CD-NZ 3.32Å; E385-K400 WeakPolarHBondContact OE1-CE 3.48Å; E385-K400 IonicContact OE1-NZ 2.71Å; E385-K400 PolarHBondContact OE1-NZ 3.46Å; E385-K400 IonicContact OE2-NZ 3.53Å; E385-K400 PolarHBondContact OE2-NZ 2.91Å
386N94.4Very high92.1Very high0 Ų048 Ų480%023%0.225CC..THydrogen-bonded Turntrans56.461.2175.3-171.542.7000113.5F285 H286 Y302 E383 W384F285-N386 VanDerWaalsContact CD2-OD1 3.29Å; F285-N386 WeakPolarHBondContact CD2-OD1 3.47Å; H286-N386 VanDerWaalsContact CE1-CG 3.46Å; H286-N386 PolarHBondContact N-OD1 2.87Å; H286-N386 VanDerWaalsContact N-OD1 3.13Å; H286-N386 PolarHBondContact ND1-ND2 3.09Å; H286-N386 PolarHBondContact O-ND2 3.47Å; Y302-N386 WeakPolarHBondContact CD2-ND2 3.25Å; Y302-N386 VanDerWaalsContact CG-ND2 3.35Å; E383-N386 PolarHBondContact O-N 2.89Å; E383-N386 VanDerWaalsContact O-N 3.17Å; W384-N386 PolarHBondContact O-N 3.36Å
387H92.9Very high92.1Very high1 Ų140.6 Ų40.61%0.00520%0.196CC..  trans-70.3139173.3-67.8-77.5000111.9R282 F285 E385 S392 H396R282-H387 PolarHBondContact NE-O 3.2Å; F285-H387 WeakPolarHBondContact CD2-O 3.41Å; E385-H387 IonicContact OE2-CD2 3.33Å; E385-H387 IonicContact OE2-CE1 3.76Å; E385-H387 IonicContact OE2-NE2 2.62Å; E385-H387 PolarHBondContact OE2-NE2 3.44Å; H387-S392 PolarHBondContact ND1-OG 3.38Å; H387-H396 AromaticContact CE1-CD2 3.62Å; H387-H396 AromaticContact CE1-CE1 3.58Å; H387-H396 AromaticContact CE1-CG 3.47Å; H387-H396 VanDerWaalsContact CE1-CG 3.47Å; H387-H396 AromaticContact CE1-ND1 3.44Å; H387-H396 PolarHBondContact CE1-ND1 2.95Å; H387-H396 AromaticContact CE1-NE2 3.68Å; H387-H396 AromaticContact ND1-ND1 3.98Å; H387-H396 AromaticContact NE2-CD2 3.99Å; H387-H396 AromaticContact NE2-CG 3.66Å; H387-H396 AromaticContact NE2-ND1 3.99Å
388R89.8Confident91.9Very high51 Ų5139.9 Ų39.919%0.19219%0.189CC..SBendtrans-70.1-50.6179.5-179-178.1174.6-76.4-4.7111.9E279 P281 R282 F285 E299E279-R388 PolarHBondContact O-NH1 3.15Å; E279-R388 PolarHBondContact O-NH2 3.26Å; P281-R388 CarbonylContact C-O 3.48Å; P281-R388 VanDerWaalsContact CA-O 3.28Å; P281-R388 WeakPolarHBondContact CA-O 3.24Å; P281-R388 HydrophobicContact CB-CG 3.99Å; P281-R388 HydrophobicContact CG-CG 4.2Å; R282-R388 PolarHBondContact N-O 2.93Å; F285-R388 HydrophobicContact CD1-CB 4.44Å; F285-R388 HydrophobicContact CD1-CG 4.18Å; F285-R388 HydrophobicContact CD2-CB 4.18Å; F285-R388 HydrophobicContact CE1-CB 4.12Å; F285-R388 HydrophobicContact CE1-CG 3.88Å; F285-R388 HydrophobicContact CE2-CB 3.93Å; F285-R388 HydrophobicContact CG-CB 4.43Å; F285-R388 HydrophobicContact CZ-CB 3.89Å; F285-R388 HydrophobicContact CZ-CG 4.13Å; E299-R388 IonicContact OE1-CZ 2.72Å; E299-R388 IonicContact OE1-NE 3.56Å; E299-R388 PolarHBondContact OE1-NE 2.94Å; E299-R388 IonicContact OE1-NH2 2.91Å; E299-R388 PolarHBondContact OE1-NH2 3.14Å; E299-R388 VanDerWaalsContact OE1-NH2 3.08Å; E299-R388 IonicContact OE2-CZ 2.95Å; E299-R388 IonicContact OE2-NE 3.27Å; E299-R388 IonicContact OE2-NH2 2.91Å; E299-R388 PolarHBondContact OE2-NH2 2.98Å
389L88.8Confident91.7Very high31 Ų3144 Ų4416%0.16221%0.211CC..SBendtrans-96.6146.2-175.3-64.8177.3000111E279 S391 S392 Y393E279-L389 HydrophobicContact CB-CD2 3.83Å; L389-S391 VanDerWaalsContact C-N 3.35Å; L389-S392 PolarHBondContact O-N 3.2Å; L389-Y393 PolarHBondContact O-N 3.36Å
390E85.7Confident91.8Very high82 Ų8241.5 Ų41.538%0.38320%0.199SC..Hα-helixtrans-62.4-43.2174.8-171.955.9-148.300111.2R282 S392 Y393 Q394R282-E390 HydrophobicContact CB-CB 4.29Å; R282-E390 WeakPolarHBondContact CD-OE2 3.49Å; E390-S392 VanDerWaalsContact C-N 3.3Å; E390-S392 PolarHBondContact O-N 2.92Å; E390-Y393 WeakPolarHBondContact O-CB 3.46Å; E390-Y393 PolarHBondContact O-N 3.49Å; E390-Y393 VanDerWaalsContact O-N 3.15Å; E390-Q394 HydrophobicContact CG-CG 4.36Å; E390-Q394 WeakPolarHBondContact O-CG 3.42Å; E390-Q394 PolarHBondContact O-N 3.25Å; E390-Q394 PolarHBondContact OE1-NE2 3.13Å
391S84.6Confident91.7Very high38 Ų3835.1 Ų35.127%0.26617%0.171SC..Hα-helixtrans-58.2-39175.256.30000113.2L389 N395L389-S391 VanDerWaalsContact C-N 3.35Å; S391-N395 WeakPolarHBondContact O-CB 3.36Å; S391-N395 PolarHBondContact O-N 2.84Å; S391-N395 PolarHBondContact O-ND2 3.49Å; S391-N395 PolarHBondContact O-OD1 3.3Å
392S88.9Confident91.6Very high36 Ų3635.1 Ų35.125%0.25217%0.171SC..Hα-helixtrans-68.8-41.7176.2-174.50000112H387 L389 E390 H396H387-S392 PolarHBondContact ND1-OG 3.38Å; L389-S392 PolarHBondContact O-N 3.2Å; E390-S392 VanDerWaalsContact C-N 3.3Å; E390-S392 PolarHBondContact O-N 2.92Å; S392-H396 PolarHBondContact O-N 3.28Å; S392-H396 PolarHBondContact O-ND1 3.44Å
393Y91.2Very high91.5Very high23 Ų2337.2 Ų37.29%0.0918%0.184CC..Hα-helixtrans-58.8-53.6175.2170.2-94.4000110.7T382 E383 L389 E390 N395 H396 L397T382-Y393 HydrophobicContact CG2-CD2 3.62Å; T382-Y393 HydrophobicContact CG2-CE2 3.71Å; T382-Y393 HydrophobicContact CG2-CG 4.36Å; E383-Y393 HydrophobicContact CB-CE2 4.41Å; L389-Y393 PolarHBondContact O-N 3.36Å; E390-Y393 WeakPolarHBondContact O-CB 3.46Å; E390-Y393 PolarHBondContact O-N 3.49Å; E390-Y393 VanDerWaalsContact O-N 3.15Å; Y393-N395 PolarHBondContact O-N 3.17Å; Y393-H396 PolarHBondContact O-N 3.1Å; Y393-L397 HydrophobicContact CE1-CD2 4.12Å; Y393-L397 PolarHBondContact O-N 2.98Å
394Q88.5Confident91.6Very high71 Ų7135 Ų3533%0.33217%0.173SC..Hα-helixtrans-59.3-45.6179.8-66.9-60.8-2500111.4E390 H396 L397 V398E390-Q394 HydrophobicContact CG-CG 4.36Å; E390-Q394 WeakPolarHBondContact O-CG 3.42Å; E390-Q394 PolarHBondContact O-N 3.25Å; E390-Q394 PolarHBondContact OE1-NE2 3.13Å; Q394-H396 VanDerWaalsContact C-N 3.33Å; Q394-H396 PolarHBondContact O-N 3.35Å; Q394-L397 PolarHBondContact O-N 3.24Å; Q394-V398 WeakPolarHBondContact O-CB 3.37Å; Q394-V398 WeakPolarHBondContact O-CG2 3.33Å; Q394-V398 PolarHBondContact O-N 3.2Å
395N90.1Very high91.5Very high52 Ų5230.8 Ų30.828%0.27816%0.158SC..Hα-helixtrans-55.9-42.9177.4-77.3-4.5000113.5S391 Y393 L399 V553S391-N395 WeakPolarHBondContact O-CB 3.36Å; S391-N395 PolarHBondContact O-N 2.84Å; S391-N395 PolarHBondContact O-ND2 3.49Å; S391-N395 PolarHBondContact O-OD1 3.3Å; Y393-N395 PolarHBondContact O-N 3.17Å; N395-L399 WeakPolarHBondContact O-CB 3.46Å; N395-L399 PolarHBondContact O-N 2.95Å; N395-L399 VanDerWaalsContact O-N 3.09Å; N395-V553 HydrophobicContact CB-CG2 3.41Å; N395-V553 VanDerWaalsContact CB-CG2 3.41Å; N395-V553 WeakPolarHBondContact OD1-CG2 3.38Å
396H92.5Very high91.3Very high58 Ų5831.8 Ų31.827%0.26916%0.163SC..Hα-helixtrans-76.2-33.4179.7-73.574.6000112.4T382 H387 S392 Y393 Q394 K400T382-H396 HydrophobicContact CG2-CB 4.07Å; H387-H396 AromaticContact CE1-CD2 3.62Å; H387-H396 AromaticContact CE1-CE1 3.58Å; H387-H396 AromaticContact CE1-CG 3.47Å; H387-H396 VanDerWaalsContact CE1-CG 3.47Å; H387-H396 AromaticContact CE1-ND1 3.44Å; H387-H396 PolarHBondContact CE1-ND1 2.95Å; H387-H396 AromaticContact CE1-NE2 3.68Å; H387-H396 AromaticContact ND1-ND1 3.98Å; H387-H396 AromaticContact NE2-CD2 3.99Å; H387-H396 AromaticContact NE2-CG 3.66Å; H387-H396 AromaticContact NE2-ND1 3.99Å; S392-H396 PolarHBondContact O-N 3.28Å; S392-H396 PolarHBondContact O-ND1 3.44Å; Y393-H396 PolarHBondContact O-N 3.1Å; Q394-H396 VanDerWaalsContact C-N 3.33Å; Q394-H396 PolarHBondContact O-N 3.35Å; H396-K400 WeakPolarHBondContact O-CG 3.47Å; H396-K400 PolarHBondContact O-N 2.92Å; H396-K400 PolarHBondContact O-NZ 2.86Å
397L93.4Very high91.2Very high15 Ų1535.4 Ų35.48%0.07918%0.178CC..Hα-helixtrans-65.6-50.4173.7178.358.9000110.2A378 E379 T382 Y393 Q394 L399 K400 V401A378-L397 HydrophobicContact CB-CD1 3.95Å; E379-L397 HydrophobicContact CB-CD1 4.45Å; E379-L397 HydrophobicContact CG-CD1 3.84Å; E379-L397 HydrophobicContact CG-CD2 3.93Å; T382-L397 HydrophobicContact CG2-CB 4.17Å; Y393-L397 HydrophobicContact CE1-CD2 4.12Å; Y393-L397 PolarHBondContact O-N 2.98Å; Q394-L397 PolarHBondContact O-N 3.24Å; L397-L399 VanDerWaalsContact C-N 3.32Å; L397-L399 PolarHBondContact O-N 3.5Å; L397-K400 PolarHBondContact O-N 2.67Å; L397-V401 HydrophobicContact CD1-CG2 4.03Å; L397-V401 WeakPolarHBondContact O-CG2 3.39Å; L397-V401 PolarHBondContact O-N 3.15Å; L397-V401 VanDerWaalsContact O-N 3.07Å
398V91.6Very high91Very high9 Ų935.4 Ų35.46%0.05518%0.179CC..Hα-helixtrans-52.5-51.4176.81700000109.9Q394 K400 V401 L402 F494 V553 W554Q394-V398 WeakPolarHBondContact O-CB 3.37Å; Q394-V398 WeakPolarHBondContact O-CG2 3.33Å; Q394-V398 PolarHBondContact O-N 3.2Å; V398-K400 VanDerWaalsContact C-N 3.35Å; V398-K400 PolarHBondContact O-N 2.63Å; V398-V401 PolarHBondContact O-N 3.49Å; V398-L402 WeakPolarHBondContact O-CB 3.43Å; V398-L402 PolarHBondContact O-N 3.32Å; V398-F494 HydrophobicContact CB-CD2 4.21Å; V398-F494 HydrophobicContact CB-CE2 4.03Å; V398-F494 HydrophobicContact CG1-CD2 4.36Å; V398-F494 HydrophobicContact CG1-CE2 4.02Å; V398-F494 HydrophobicContact CG2-CD2 3.58Å; V398-F494 HydrophobicContact CG2-CE2 3.92Å; V398-V553 HydrophobicContact CG1-CB 4.38Å; V398-V553 HydrophobicContact CG1-CG1 4.18Å; V398-W554 HydrophobicContact CG1-CD2 4.23Å; V398-W554 HydrophobicContact CG1-CH2 4.22Å; V398-W554 HydrophobicContact CG1-CZ2 3.79Å
399L92Very high90.8Very high86 Ų8634 Ų3445%0.4518%0.176SC..Hα-helixtrans-57.9-44.5-178.8-177.565000112.6N395 L397 V403N395-L399 WeakPolarHBondContact O-CB 3.46Å; N395-L399 PolarHBondContact O-N 2.95Å; N395-L399 VanDerWaalsContact O-N 3.09Å; L397-L399 VanDerWaalsContact C-N 3.32Å; L397-L399 PolarHBondContact O-N 3.5Å; L399-V403 HydrophobicContact CD1-CG2 4.21Å; L399-V403 VanDerWaalsContact O-CG2 3.26Å; L399-V403 WeakPolarHBondContact O-CG2 3.5Å; L399-V403 PolarHBondContact O-N 3.4Å
400K94.1Very high90.9Very high16 Ų1632.5 Ų32.57%0.0717%0.169CC..Hα-helixtrans-64.3-47.7-179.5-71.7177.5-174.576.30112.1S315 V319 Y374 A378 T382 E385 H396 L397 V398 F404S315-K400 WeakPolarHBondContact OG-CE 3.4Å; V319-K400 HydrophobicContact CG2-CB 4.5Å; V319-K400 HydrophobicContact CG2-CD 4.36Å; V319-K400 HydrophobicContact CG2-CG 4.03Å; Y374-K400 VanDerWaalsContact CE1-O 3.23Å; Y374-K400 WeakPolarHBondContact CE1-O 3.39Å; Y374-K400 PolarHBondContact OH-O 2.94Å; A378-K400 HydrophobicContact CB-CB 4.25Å; A378-K400 HydrophobicContact CB-CD 4.46Å; T382-K400 PolarHBondContact OG1-NZ 3.42Å; E385-K400 VanDerWaalsContact CD-NZ 3.32Å; E385-K400 WeakPolarHBondContact OE1-CE 3.48Å; E385-K400 IonicContact OE1-NZ 2.71Å; E385-K400 PolarHBondContact OE1-NZ 3.46Å; E385-K400 IonicContact OE2-NZ 3.53Å; E385-K400 PolarHBondContact OE2-NZ 2.91Å; H396-K400 WeakPolarHBondContact O-CG 3.47Å; H396-K400 PolarHBondContact O-N 2.92Å; H396-K400 PolarHBondContact O-NZ 2.86Å; L397-K400 PolarHBondContact O-N 2.67Å; V398-K400 VanDerWaalsContact C-N 3.35Å; V398-K400 PolarHBondContact O-N 2.63Å; K400-F404 PolarHBondContact O-N 3.18Å
401V94Very high91.2Very high4 Ų429.1 Ų29.12%0.02415%0.154CC..Hα-helixtrans-69.7-40.5-178.1-178.10000110.7Y374 A378 L397 V398 F404 N405 F494Y374-V401 HydrophobicContact CE1-CG2 4.45Å; A378-V401 HydrophobicContact CB-CG2 3.79Å; L397-V401 HydrophobicContact CD1-CG2 4.03Å; L397-V401 WeakPolarHBondContact O-CG2 3.39Å; L397-V401 PolarHBondContact O-N 3.15Å; L397-V401 VanDerWaalsContact O-N 3.07Å; V398-V401 PolarHBondContact O-N 3.49Å; V401-F404 PolarHBondContact O-N 2.84Å; V401-N405 VanDerWaalsContact CG1-ND2 3.34Å; V401-N405 WeakPolarHBondContact CG1-ND2 3.3Å; V401-N405 WeakPolarHBondContact O-CB 3.33Å; V401-N405 PolarHBondContact O-N 3.14Å; V401-N405 PolarHBondContact O-ND2 3.44Å; V401-F494 HydrophobicContact CB-CE1 4.25Å; V401-F494 HydrophobicContact CB-CE2 4.32Å; V401-F494 HydrophobicContact CB-CZ 3.59Å; V401-F494 HydrophobicContact CG1-CE1 3.64Å; V401-F494 HydrophobicContact CG1-CE2 4.49Å; V401-F494 HydrophobicContact CG1-CZ 3.35Å; V401-F494 HydrophobicContact CG2-CZ 4.5Å
402L93.6Very high91.5Very high13 Ų1327.7 Ų27.77%0.06815%0.145CC..Hα-helixtrans-60.9-49.2177.4-175.7153.8000112.3V398 F404 N405 F406 F501 W554 A557V398-L402 WeakPolarHBondContact O-CB 3.43Å; V398-L402 PolarHBondContact O-N 3.32Å; L402-F404 VanDerWaalsContact C-N 3.3Å; L402-F404 PolarHBondContact O-N 3.3Å; L402-N405 PolarHBondContact O-N 3.25Å; L402-F406 VanDerWaalsContact O-CB 3.23Å; L402-F406 WeakPolarHBondContact O-CB 3.45Å; L402-F406 PolarHBondContact O-N 3.17Å; L402-F501 HydrophobicContact CD1-CD1 4.3Å; L402-F501 HydrophobicContact CD1-CE1 4.17Å; L402-F501 HydrophobicContact CD1-CE2 4.44Å; L402-F501 HydrophobicContact CD1-CG 4.47Å; L402-F501 HydrophobicContact CD1-CZ 4.22Å; L402-F501 HydrophobicContact CD2-CE1 3.84Å; L402-F501 HydrophobicContact CD2-CZ 3.76Å; L402-F501 HydrophobicContact CG-CD1 4.22Å; L402-F501 HydrophobicContact CG-CE1 3.81Å; L402-F501 HydrophobicContact CG-CZ 4.12Å; L402-W554 HydrophobicContact CD1-CE3 3.79Å; L402-W554 HydrophobicContact CD1-CH2 4.11Å; L402-W554 HydrophobicContact CD1-CZ3 3.4Å; L402-W554 HydrophobicContact CG-CZ3 4.38Å; L402-A557 HydrophobicContact CD1-CB 3.36Å; L402-A557 HydrophobicContact CD2-CB 4.36Å
403V93.8Very high91.6Very high45 Ų4526 Ų2627%0.27313%0.133SC..Hα-helixtrans-60.6-43.9179.7171.70000110.3L323 L399 F406 F407L323-V403 HydrophobicContact CD1-CG1 3.83Å; L323-V403 HydrophobicContact CD2-CG1 4.19Å; L399-V403 HydrophobicContact CD1-CG2 4.21Å; L399-V403 VanDerWaalsContact O-CG2 3.26Å; L399-V403 WeakPolarHBondContact O-CG2 3.5Å; L399-V403 PolarHBondContact O-N 3.4Å; V403-F406 PolarHBondContact O-N 2.98Å; V403-F407 HydrophobicContact CG1-CD2 4.07Å; V403-F407 HydrophobicContact CG1-CE2 4.18Å; V403-F407 WeakPolarHBondContact O-CD2 3.37Å; V403-F407 PolarHBondContact O-N 3.1Å; V403-F407 VanDerWaalsContact O-N 3.09Å
404F94.8Very high91.8Very high5 Ų527 Ų272%0.02214%0.138CC..Hα-helixtrans-64.3-48.2178.5-176.2-102000112.9C322 L323 M370 Y374 K400 V401 L402 F406 F407 N408C322-F404 HydrophobicContact CB-CD2 4.18Å; C322-F404 HydrophobicContact CB-CE2 4.03Å; L323-F404 HydrophobicContact CD2-CD2 4.18Å; M370-F404 HydrophobicContact CB-CE1 4.43Å; M370-F404 HydrophobicContact CB-CZ 4.19Å; M370-F404 HydrophobicContact CE-CE2 4.48Å; M370-F404 HydrophobicContact CE-CZ 4Å; Y374-F404 HydrophobicContact CD1-CB 3.59Å; Y374-F404 AromaticContact CD1-CD1 3.43Å; Y374-F404 HydrophobicContact CD1-CD1 3.43Å; Y374-F404 VanDerWaalsContact CD1-CD1 3.43Å; Y374-F404 HydrophobicContact CD1-CD2 4.25Å; Y374-F404 HydrophobicContact CD1-CE1 4.1Å; Y374-F404 AromaticContact CD1-CG 3.49Å; Y374-F404 HydrophobicContact CD1-CG 3.49Å; Y374-F404 VanDerWaalsContact CD1-CG 3.49Å; Y374-F404 HydrophobicContact CD2-CB 4.42Å; Y374-F404 HydrophobicContact CD2-CD1 4.17Å; Y374-F404 AromaticContact CD2-CD2 3.74Å; Y374-F404 HydrophobicContact CD2-CD2 3.74Å; Y374-F404 HydrophobicContact CD2-CE1 4.31Å; Y374-F404 AromaticContact CD2-CE2 3.95Å; Y374-F404 HydrophobicContact CD2-CE2 3.95Å; Y374-F404 AromaticContact CD2-CG 3.85Å; Y374-F404 HydrophobicContact CD2-CG 3.85Å; Y374-F404 HydrophobicContact CD2-CZ 4.22Å; Y374-F404 HydrophobicContact CE1-CB 3.28Å; Y374-F404 HydrophobicContact CE1-CD1 4.09Å; Y374-F404 HydrophobicContact CE1-CD2 4.38Å; Y374-F404 AromaticContact CE1-CG 3.69Å; Y374-F404 HydrophobicContact CE1-CG 3.69Å; Y374-F404 HydrophobicContact CE2-CB 4.16Å; Y374-F404 AromaticContact CE2-CD2 3.88Å; Y374-F404 HydrophobicContact CE2-CD2 3.88Å; Y374-F404 HydrophobicContact CE2-CE2 4.46Å; Y374-F404 HydrophobicContact CE2-CG 4.02Å; Y374-F404 HydrophobicContact CG-CB 4.14Å; Y374-F404 AromaticContact CG-CD1 3.46Å; Y374-F404 HydrophobicContact CG-CD1 3.46Å; Y374-F404 VanDerWaalsContact CG-CD1 3.46Å; Y374-F404 AromaticContact CG-CD2 3.91Å; Y374-F404 HydrophobicContact CG-CD2 3.91Å; Y374-F404 AromaticContact CG-CE1 3.67Å; Y374-F404 HydrophobicContact CG-CE1 3.67Å; Y374-F404 HydrophobicContact CG-CE2 4.14Å; Y374-F404 AromaticContact CG-CG 3.56Å; Y374-F404 HydrophobicContact CG-CG 3.56Å; Y374-F404 HydrophobicContact CG-CZ 4.01Å; Y374-F404 AromaticContact CZ-CG 3.91Å; K400-F404 PolarHBondContact O-N 3.18Å; V401-F404 PolarHBondContact O-N 2.84Å; L402-F404 VanDerWaalsContact C-N 3.3Å; L402-F404 PolarHBondContact O-N 3.3Å; F404-F406 VanDerWaalsContact C-N 3.34Å; F404-F406 PolarHBondContact O-N 3.47Å; F404-F407 PolarHBondContact O-N 3Å; F404-N408 WeakPolarHBondContact CD1-ND2 3.28Å; F404-N408 WeakPolarHBondContact CE1-ND2 2.84Å; F404-N408 WeakPolarHBondContact CZ-ND2 3.36Å; F404-N408 PolarHBondContact O-N 3.16Å
405N90.9Very high92Very high10 Ų1026.3 Ų26.35%0.05313%0.132CC..Hα-helixtrans-63.5-40.4178.1-74.2-25.9000111.8N371 V401 L402 F407 N408 C409 L498N371-N405 PolarHBondContact OD1-OD1 3.05Å; V401-N405 VanDerWaalsContact CG1-ND2 3.34Å; V401-N405 WeakPolarHBondContact CG1-ND2 3.3Å; V401-N405 WeakPolarHBondContact O-CB 3.33Å; V401-N405 PolarHBondContact O-N 3.14Å; V401-N405 PolarHBondContact O-ND2 3.44Å; L402-N405 PolarHBondContact O-N 3.25Å; N405-F407 PolarHBondContact O-N 3.44Å; N405-N408 PolarHBondContact O-N 2.98Å; N405-C409 WeakPolarHBondContact O-CB 3.29Å; N405-C409 PolarHBondContact O-N 2.7Å; N405-C409 PolarHBondContact O-SG 3.31Å; N405-L498 HydrophobicContact CB-CD1 4.21Å; N405-L498 WeakPolarHBondContact ND2-CD2 3.33Å
406F91.7Very high92Very high22 Ų2224 Ų2410%0.09612%0.12CC..Hα-helixtrans-56.3-50.2174.3174.9-91.8000111.3L402 V403 F404 C409 F410 F414 F501 L509 M561 I564L402-F406 VanDerWaalsContact O-CB 3.23Å; L402-F406 WeakPolarHBondContact O-CB 3.45Å; L402-F406 PolarHBondContact O-N 3.17Å; V403-F406 PolarHBondContact O-N 2.98Å; F404-F406 VanDerWaalsContact C-N 3.34Å; F404-F406 PolarHBondContact O-N 3.47Å; F406-C409 PolarHBondContact O-N 3.03Å; F406-F410 AromaticContact CD2-CD2 3.3Å; F406-F410 HydrophobicContact CD2-CD2 3.3Å; F406-F410 AromaticContact CD2-CE2 3.64Å; F406-F410 HydrophobicContact CD2-CE2 3.64Å; F406-F410 HydrophobicContact CD2-CG 4.39Å; F406-F410 AromaticContact CE2-CD2 3.44Å; F406-F410 HydrophobicContact CE2-CD2 3.44Å; F406-F410 VanDerWaalsContact CE2-CD2 3.44Å; F406-F410 AromaticContact CE2-CE2 3.92Å; F406-F410 HydrophobicContact CE2-CE2 3.92Å; F406-F410 HydrophobicContact CE2-CG 4.18Å; F406-F410 AromaticContact CG-CD2 3.95Å; F406-F410 HydrophobicContact CG-CD2 3.95Å; F406-F410 HydrophobicContact CZ-CD2 4.2Å; F406-F410 WeakPolarHBondContact O-CB 3.5Å; F406-F410 VanDerWaalsContact O-CD2 3.24Å; F406-F410 WeakPolarHBondContact O-CD2 3.47Å; F406-F410 PolarHBondContact O-N 2.85Å; F406-F414 HydrophobicContact CE1-CE2 4.19Å; F406-F414 AromaticContact CZ-CE2 3.89Å; F406-F414 HydrophobicContact CZ-CE2 3.89Å; F406-F414 HydrophobicContact CZ-CZ 4.25Å; F406-F501 HydrophobicContact CB-CE1 4.44Å; F406-F501 HydrophobicContact CD2-CE1 4.21Å; F406-F501 HydrophobicContact CD2-CZ 4.28Å; F406-L509 HydrophobicContact CE2-CD1 4.2Å; F406-M561 HydrophobicContact CD2-CE 3.45Å; F406-M561 VanDerWaalsContact CD2-CE 3.45Å; F406-M561 HydrophobicContact CD2-SD 4.37Å; F406-M561 HydrophobicContact CE2-CE 3.35Å; F406-M561 HydrophobicContact CE2-SD 3.66Å; F406-I564 HydrophobicContact CZ-CD1 4.12Å
407F91.4Very high92Very high75 Ų7521.2 Ų21.233%0.32911%0.107SC..Hα-helixtrans-63-45177.9-90.4-92.9000111.8L323 V403 F404 N405 C409 A411L323-F407 HydrophobicContact CD1-CD2 4.33Å; L323-F407 HydrophobicContact CD1-CE2 4.29Å; L323-F407 HydrophobicContact CD2-CB 3.78Å; L323-F407 HydrophobicContact CD2-CD2 3.75Å; L323-F407 HydrophobicContact CD2-CG 3.8Å; V403-F407 HydrophobicContact CG1-CD2 4.07Å; V403-F407 HydrophobicContact CG1-CE2 4.18Å; V403-F407 WeakPolarHBondContact O-CD2 3.37Å; V403-F407 PolarHBondContact O-N 3.1Å; V403-F407 VanDerWaalsContact O-N 3.09Å; F404-F407 PolarHBondContact O-N 3Å; N405-F407 PolarHBondContact O-N 3.44Å; F407-C409 VanDerWaalsContact C-N 3.33Å; F407-C409 PolarHBondContact O-N 3.38Å; F407-A411 WeakPolarHBondContact O-CB 3.45Å; F407-A411 PolarHBondContact O-N 3.4Å
408N88.9Confident92Very high2 Ų223.5 Ų23.51%0.01112%0.116CC..Hα-helixtrans-61.8-39.2179.7-74.4-2.7000113.1S326 I367 N371 F404 N405S326-N408 WeakPolarHBondContact CB-OD1 3.37Å; S326-N408 PolarHBondContact OG-OD1 3.24Å; I367-N408 HydrophobicContact CG2-CB 4.23Å; N371-N408 PolarHBondContact OD1-ND2 2.9Å; F404-N408 WeakPolarHBondContact CD1-ND2 3.28Å; F404-N408 WeakPolarHBondContact CE1-ND2 2.84Å; F404-N408 WeakPolarHBondContact CZ-ND2 3.36Å; F404-N408 PolarHBondContact O-N 3.16Å; N405-N408 PolarHBondContact O-N 2.98Å
409C87.3Confident92Very high21 Ų2127.4 Ų27.414%0.14214%0.14CC..Hα-helixtrans-78.4-40.5-178.7-65.70000112.8N405 F406 F407 L502N405-C409 WeakPolarHBondContact O-CB 3.29Å; N405-C409 PolarHBondContact O-N 2.7Å; N405-C409 PolarHBondContact O-SG 3.31Å; F406-C409 PolarHBondContact O-N 3.03Å; F407-C409 VanDerWaalsContact C-N 3.33Å; F407-C409 PolarHBondContact O-N 3.38Å; C409-L502 HydrophobicContact CB-CD2 4.16Å
410F91Very high91.8Very high0 Ų026.9 Ų26.90%014%0.136CC..Hα-helixtrans-103.6-15.9-169.3-61.9-68000114.7F406 S412 L413 F414 L502 Y506 L509 F510 M561F406-F410 AromaticContact CD2-CD2 3.3Å; F406-F410 HydrophobicContact CD2-CD2 3.3Å; F406-F410 AromaticContact CD2-CE2 3.64Å; F406-F410 HydrophobicContact CD2-CE2 3.64Å; F406-F410 HydrophobicContact CD2-CG 4.39Å; F406-F410 AromaticContact CE2-CD2 3.44Å; F406-F410 HydrophobicContact CE2-CD2 3.44Å; F406-F410 VanDerWaalsContact CE2-CD2 3.44Å; F406-F410 AromaticContact CE2-CE2 3.92Å; F406-F410 HydrophobicContact CE2-CE2 3.92Å; F406-F410 HydrophobicContact CE2-CG 4.18Å; F406-F410 AromaticContact CG-CD2 3.95Å; F406-F410 HydrophobicContact CG-CD2 3.95Å; F406-F410 HydrophobicContact CZ-CD2 4.2Å; F406-F410 WeakPolarHBondContact O-CB 3.5Å; F406-F410 VanDerWaalsContact O-CD2 3.24Å; F406-F410 WeakPolarHBondContact O-CD2 3.47Å; F406-F410 PolarHBondContact O-N 2.85Å; F410-S412 VanDerWaalsContact C-N 3.34Å; F410-S412 PolarHBondContact O-N 2.91Å; F410-L413 HydrophobicContact CD1-CD1 4.13Å; F410-L413 PolarHBondContact O-N 3.1Å; F410-F414 HydrophobicContact CB-CD2 4.03Å; F410-F414 HydrophobicContact CB-CE2 3.75Å; F410-F414 HydrophobicContact CB-CZ 4.5Å; F410-F414 WeakPolarHBondContact O-CD2 3.3Å; F410-F414 WeakPolarHBondContact O-CG 3.25Å; F410-F414 PolarHBondContact O-N 3.48Å; F410-L502 HydrophobicContact CE2-CD2 3.75Å; F410-L502 HydrophobicContact CZ-CD2 4.27Å; F410-Y506 HydrophobicContact CD1-CD1 4.34Å; F410-Y506 HydrophobicContact CD1-CE1 4.16Å; F410-Y506 AromaticContact CE1-CD1 3.51Å; F410-Y506 HydrophobicContact CE1-CD1 3.51Å; F410-Y506 AromaticContact CE1-CE1 3.57Å; F410-Y506 HydrophobicContact CE1-CE1 3.57Å; F410-Y506 HydrophobicContact CE1-CG 4.07Å; F410-Y506 HydrophobicContact CZ-CD1 4.29Å; F410-Y506 HydrophobicContact CZ-CE1 4.29Å; F410-Y506 HydrophobicContact CZ-CG 4.49Å; F410-L509 HydrophobicContact CD1-CD1 3.75Å; F410-L509 HydrophobicContact CD2-CD1 4.36Å; F410-L509 HydrophobicContact CE1-CD1 3.9Å; F410-L509 HydrophobicContact CG-CD1 3.99Å; F410-L509 HydrophobicContact CZ-CD1 4.3Å; F410-F510 AromaticContact CD1-CE2 3.94Å; F410-F510 HydrophobicContact CD1-CE2 3.94Å; F410-F510 HydrophobicContact CE1-CE2 4.45Å; F410-M561 HydrophobicContact CE2-CE 3.88Å; F410-M561 HydrophobicContact CZ-CE 4.33Å
411A91.9Very high91.6Very high10 Ų1031 Ų318%0.08316%0.156CC..Hα-helixtrans-61.8-40.2-177.600000112.7L327 M330 F407 F414 Y415L327-A411 HydrophobicContact CD2-CB 3.8Å; M330-A411 HydrophobicContact SD-CB 3.62Å; F407-A411 WeakPolarHBondContact O-CB 3.45Å; F407-A411 PolarHBondContact O-N 3.4Å; A411-F414 PolarHBondContact O-N 3.34Å; A411-Y415 WeakPolarHBondContact O-CB 3.47Å; A411-Y415 PolarHBondContact O-N 3.38Å
412S90.1Very high91.3Very high9 Ų934.1 Ų34.16%0.06317%0.173CC..Hα-helixtrans-64.2-41.4176.556.80000111.6M330 F410 Y415 I416M330-S412 PolarHBondContact SD-N 3.49Å; M330-S412 VanDerWaalsContact SD-N 3.44Å; F410-S412 VanDerWaalsContact C-N 3.34Å; F410-S412 PolarHBondContact O-N 2.91Å; S412-Y415 WeakPolarHBondContact O-CB 3.4Å; S412-Y415 PolarHBondContact O-N 2.96Å; S412-I416 WeakPolarHBondContact O-CD1 3.49Å; S412-I416 VanDerWaalsContact O-CG1 3.27Å; S412-I416 WeakPolarHBondContact O-CG1 3.44Å; S412-I416 PolarHBondContact O-N 3.44Å
413L91.2Very high90.9Very high0 Ų036.4 Ų36.40%018%0.184CC..Hα-helixtrans-65.4-41.9176.3-63.1177.9000111.7F410 Y415 I416 A417 L426 L430 L433 Y506 F510F410-L413 HydrophobicContact CD1-CD1 4.13Å; F410-L413 PolarHBondContact O-N 3.1Å; L413-Y415 VanDerWaalsContact C-N 3.31Å; L413-Y415 PolarHBondContact O-N 3.41Å; L413-I416 HydrophobicContact CD2-CD1 4.41Å; L413-I416 PolarHBondContact O-N 2.87Å; L413-A417 WeakPolarHBondContact O-CB 3.45Å; L413-A417 PolarHBondContact O-N 2.78Å; L413-L426 HydrophobicContact CB-CD1 4.12Å; L413-L426 HydrophobicContact CD2-CD1 3.99Å; L413-L430 HydrophobicContact CD1-CD1 4.07Å; L413-L433 HydrophobicContact CD1-CD1 4.36Å; L413-L433 HydrophobicContact CD2-CD1 4.04Å; L413-L433 HydrophobicContact CG-CD1 4.29Å; L413-Y506 HydrophobicContact CD1-CD1 4.14Å; L413-Y506 HydrophobicContact CD1-CE1 3.8Å; L413-F510 HydrophobicContact CB-CE1 4.22Å; L413-F510 HydrophobicContact CB-CE2 3.93Å; L413-F510 HydrophobicContact CB-CZ 3.56Å; L413-F510 HydrophobicContact CD1-CD2 4.28Å; L413-F510 HydrophobicContact CD1-CE2 3.78Å; L413-F510 HydrophobicContact CD1-CZ 4.3Å
414F94.3Very high90.5Very high44 Ų4438.8 Ų38.819%0.19320%0.198CC..Hα-helixtrans-63.8-36.6173.6-72.8-46.8000112.5F406 F410 A411 F418 L509 F510 I564 T568F406-F414 HydrophobicContact CE1-CE2 4.19Å; F406-F414 AromaticContact CZ-CE2 3.89Å; F406-F414 HydrophobicContact CZ-CE2 3.89Å; F406-F414 HydrophobicContact CZ-CZ 4.25Å; F410-F414 HydrophobicContact CB-CD2 4.03Å; F410-F414 HydrophobicContact CB-CE2 3.75Å; F410-F414 HydrophobicContact CB-CZ 4.5Å; F410-F414 WeakPolarHBondContact O-CD2 3.3Å; F410-F414 WeakPolarHBondContact O-CG 3.25Å; F410-F414 PolarHBondContact O-N 3.48Å; A411-F414 PolarHBondContact O-N 3.34Å; F414-F418 HydrophobicContact CB-CD2 4.27Å; F414-F418 AromaticContact CD1-CD2 3.97Å; F414-F418 HydrophobicContact CD1-CD2 3.97Å; F414-F418 AromaticContact CD1-CE2 3.52Å; F414-F418 HydrophobicContact CD1-CE2 3.52Å; F414-F418 HydrophobicContact CE1-CE2 4.07Å; F414-F418 HydrophobicContact CG-CE2 4.47Å; F414-F418 WeakPolarHBondContact O-CB 3.32Å; F414-F418 WeakPolarHBondContact O-CD2 3.44Å; F414-F418 PolarHBondContact O-N 3.03Å; F414-L509 HydrophobicContact CZ-CD1 3.99Å; F414-L509 HydrophobicContact CZ-CD2 4.23Å; F414-F510 HydrophobicContact CD1-CE1 4.33Å; F414-F510 HydrophobicContact CD1-CZ 4.01Å; F414-F510 HydrophobicContact CE1-CE1 4.43Å; F414-F510 AromaticContact CE1-CZ 3.97Å; F414-F510 HydrophobicContact CE1-CZ 3.97Å; F414-I564 HydrophobicContact CZ-CG2 4.31Å; F414-T568 HydrophobicContact CE1-CG2 3.93Å
415Y92.9Very high90.1Very high56 Ų5640.5 Ų40.522%0.2221%0.207CC..Hα-helixtrans-65.4-46.8174.9-174.9-91000111.7M330 M331 F334 A411 S412 L413 A417 V419 M420M330-Y415 HydrophobicContact CE-CD2 4.08Å; M330-Y415 HydrophobicContact CE-CG 4.26Å; M331-Y415 HydrophobicContact CE-CE2 4.16Å; M331-Y415 HydrophobicContact SD-CD2 4.33Å; M331-Y415 HydrophobicContact SD-CE2 3.83Å; F334-Y415 HydrophobicContact CD1-CD1 4.21Å; F334-Y415 HydrophobicContact CD1-CE1 4.13Å; F334-Y415 AromaticContact CD2-CD1 3.57Å; F334-Y415 HydrophobicContact CD2-CD1 3.57Å; F334-Y415 AromaticContact CD2-CE1 3.68Å; F334-Y415 HydrophobicContact CD2-CE1 3.68Å; F334-Y415 HydrophobicContact CD2-CG 4.13Å; F334-Y415 AromaticContact CE1-CD1 3.88Å; F334-Y415 HydrophobicContact CE1-CD1 3.88Å; F334-Y415 HydrophobicContact CE1-CE1 4.25Å; F334-Y415 AromaticContact CE2-CD1 3.18Å; F334-Y415 HydrophobicContact CE2-CD1 3.18Å; F334-Y415 AromaticContact CE2-CE1 3.81Å; F334-Y415 HydrophobicContact CE2-CE1 3.81Å; F334-Y415 AromaticContact CE2-CG 3.59Å; F334-Y415 HydrophobicContact CE2-CG 3.59Å; F334-Y415 HydrophobicContact CG-CD1 4.08Å; F334-Y415 AromaticContact CG-CE1 3.85Å; F334-Y415 HydrophobicContact CG-CE1 3.85Å; F334-Y415 AromaticContact CZ-CD1 3.36Å; F334-Y415 HydrophobicContact CZ-CD1 3.36Å; F334-Y415 HydrophobicContact CZ-CE1 4.1Å; F334-Y415 HydrophobicContact CZ-CG 4.05Å; A411-Y415 WeakPolarHBondContact O-CB 3.47Å; A411-Y415 PolarHBondContact O-N 3.38Å; S412-Y415 WeakPolarHBondContact O-CB 3.4Å; S412-Y415 PolarHBondContact O-N 2.96Å; L413-Y415 VanDerWaalsContact C-N 3.31Å; L413-Y415 PolarHBondContact O-N 3.41Å; Y415-A417 VanDerWaalsContact C-N 3.34Å; Y415-A417 PolarHBondContact O-N 3.48Å; Y415-V419 HydrophobicContact CD2-CB 3.89Å; Y415-V419 HydrophobicContact CD2-CG1 4.23Å; Y415-V419 HydrophobicContact CD2-CG2 3.76Å; Y415-V419 HydrophobicContact CE2-CB 3.9Å; Y415-V419 HydrophobicContact CE2-CG1 3.71Å; Y415-V419 HydrophobicContact CE2-CG2 4.04Å; Y415-V419 HydrophobicContact CG-CB 4.26Å; Y415-V419 HydrophobicContact CG-CG2 4.38Å; Y415-V419 WeakPolarHBondContact O-CA 3.34Å; Y415-V419 VanDerWaalsContact O-CB 3.27Å; Y415-V419 WeakPolarHBondContact O-CB 3.24Å; Y415-V419 PolarHBondContact O-N 2.92Å; Y415-M420 HydrophobicContact CD1-CE 4.07Å; Y415-M420 HydrophobicContact CD1-CG 3.97Å; Y415-M420 HydrophobicContact CD1-SD 4.27Å; Y415-M420 HydrophobicContact CE1-CE 4.22Å; Y415-M420 HydrophobicContact CE1-CG 3.62Å; Y415-M420 HydrophobicContact CE1-SD 3.84Å; Y415-M420 PolarHBondContact O-N 2.99Å
416I91.1Very high90Very high4 Ų440 Ų402%0.02120%0.204CC..Iπ-helixtrans-59.4-47.6175.4-62.8157.5000110.2F334 S412 L413 M420 Q421 D422 L425 L426F334-I416 HydrophobicContact CE1-CG1 4.12Å; F334-I416 HydrophobicContact CZ-CG1 4.05Å; S412-I416 WeakPolarHBondContact O-CD1 3.49Å; S412-I416 VanDerWaalsContact O-CG1 3.27Å; S412-I416 WeakPolarHBondContact O-CG1 3.44Å; S412-I416 PolarHBondContact O-N 3.44Å; L413-I416 HydrophobicContact CD2-CD1 4.41Å; L413-I416 PolarHBondContact O-N 2.87Å; I416-M420 HydrophobicContact CB-CE 3.92Å; I416-M420 HydrophobicContact CG1-CE 3.32Å; I416-M420 HydrophobicContact CG2-CE 4.15Å; I416-M420 CarbonylContact O-C 3.59Å; I416-Q421 PolarHBondContact O-N 2.7Å; I416-D422 WeakPolarHBondContact CG2-O 3.19Å; I416-D422 PolarHBondContact O-N 3.49Å; I416-L425 HydrophobicContact CG1-CD2 4.42Å; I416-L425 HydrophobicContact CG2-CB 4.13Å; I416-L425 HydrophobicContact CG2-CD2 4.13Å; I416-L425 HydrophobicContact CG2-CG 4.04Å; I416-L426 HydrophobicContact CB-CD1 4.37Å; I416-L426 HydrophobicContact CG2-CB 3.83Å; I416-L426 HydrophobicContact CG2-CD1 4.38Å
417A91.9Very high89.7Confident0 Ų040.5 Ų40.50%021%0.21CC..Iπ-helixtrans-64.7-50.2-176.300000113.6L413 Y415 L426 F510 L572L413-A417 WeakPolarHBondContact O-CB 3.45Å; L413-A417 PolarHBondContact O-N 2.78Å; Y415-A417 VanDerWaalsContact C-N 3.34Å; Y415-A417 PolarHBondContact O-N 3.48Å; A417-L426 HydrophobicContact CB-CD1 4.26Å; A417-L426 HydrophobicContact CB-CD2 3.71Å; A417-F510 HydrophobicContact CB-CE1 4.43Å; A417-L572 HydrophobicContact CB-CD2 4.06Å
418F93Very high89.4Confident62 Ų6242.4 Ų42.427%0.27222%0.22SC..Iπ-helixtrans-104.4-25.8-166.3-61.3-53.5000114.2F414 T568 A571 L572 M575F414-F418 HydrophobicContact CB-CD2 4.27Å; F414-F418 AromaticContact CD1-CD2 3.97Å; F414-F418 HydrophobicContact CD1-CD2 3.97Å; F414-F418 AromaticContact CD1-CE2 3.52Å; F414-F418 HydrophobicContact CD1-CE2 3.52Å; F414-F418 HydrophobicContact CE1-CE2 4.07Å; F414-F418 HydrophobicContact CG-CE2 4.47Å; F414-F418 WeakPolarHBondContact O-CB 3.32Å; F414-F418 WeakPolarHBondContact O-CD2 3.44Å; F414-F418 PolarHBondContact O-N 3.03Å; F418-T568 HydrophobicContact CE2-CG2 4.3Å; F418-T568 HydrophobicContact CZ-CG2 3.9Å; F418-A571 HydrophobicContact CD1-CB 4.43Å; F418-A571 HydrophobicContact CE1-CB 3.52Å; F418-A571 HydrophobicContact CZ-CB 3.94Å; F418-L572 HydrophobicContact CE1-CD2 4.17Å; F418-L572 HydrophobicContact CE1-CG 4.23Å; F418-L572 HydrophobicContact CZ-CG 4.4Å; F418-M575 HydrophobicContact CD1-SD 3.68Å; F418-M575 HydrophobicContact CE1-SD 4.2Å
419V92.1Very high89.2Confident92 Ų9243.5 Ų43.556%0.55823%0.228SC*.Iπ-helixtrans-97.7-53.2178.7-174.90000110.9Y415Y415-V419 HydrophobicContact CD2-CB 3.89Å; Y415-V419 HydrophobicContact CD2-CG1 4.23Å; Y415-V419 HydrophobicContact CD2-CG2 3.76Å; Y415-V419 HydrophobicContact CE2-CB 3.9Å; Y415-V419 HydrophobicContact CE2-CG1 3.71Å; Y415-V419 HydrophobicContact CE2-CG2 4.04Å; Y415-V419 HydrophobicContact CG-CB 4.26Å; Y415-V419 HydrophobicContact CG-CG2 4.38Å; Y415-V419 WeakPolarHBondContact O-CA 3.34Å; Y415-V419 VanDerWaalsContact O-CB 3.27Å; Y415-V419 WeakPolarHBondContact O-CB 3.24Å; Y415-V419 PolarHBondContact O-N 2.92Å
420M88.8Confident89.2Confident75 Ų7542.5 Ų42.537%0.36922%0.222SC..Iπ-helixtrans-78.6-28.3179.5-60.1-160.7-70.200112.9F334 Y415 I416 D422 L425F334-M420 HydrophobicContact CD1-CE 4.07Å; F334-M420 HydrophobicContact CD1-SD 4.49Å; F334-M420 HydrophobicContact CE1-CE 3.52Å; F334-M420 HydrophobicContact CE1-SD 4.47Å; F334-M420 HydrophobicContact CZ-CE 4.21Å; Y415-M420 HydrophobicContact CD1-CE 4.07Å; Y415-M420 HydrophobicContact CD1-CG 3.97Å; Y415-M420 HydrophobicContact CD1-SD 4.27Å; Y415-M420 HydrophobicContact CE1-CE 4.22Å; Y415-M420 HydrophobicContact CE1-CG 3.62Å; Y415-M420 HydrophobicContact CE1-SD 3.84Å; Y415-M420 PolarHBondContact O-N 2.99Å; I416-M420 HydrophobicContact CB-CE 3.92Å; I416-M420 HydrophobicContact CG1-CE 3.32Å; I416-M420 HydrophobicContact CG2-CE 4.15Å; I416-M420 CarbonylContact O-C 3.59Å; M420-D422 PolarHBondContact O-N 3.47Å; M420-L425 HydrophobicContact CE-CD2 3.76Å
421Q89.8Confident88.9Confident102 Ų10243.2 Ų43.248%0.47723%0.228SC..  trans59.729.5179.7-46.8-170.5-10.500113.7I416 M575I416-Q421 PolarHBondContact O-N 2.7Å; Q421-M575 HydrophobicContact CB-CE 4.23Å; Q421-M575 HydrophobicContact CG-CE 3.45Å; Q421-M575 VanDerWaalsContact CG-CE 3.45Å
422D87.8Confident88.5Confident70 Ų7046.8 Ų46.837%0.37425%0.248SC..  trans-99.498.4177.9-170.8-21.6000110.3I416 M420 V424 L425 L426I416-D422 WeakPolarHBondContact CG2-O 3.19Å; I416-D422 PolarHBondContact O-N 3.49Å; M420-D422 PolarHBondContact O-N 3.47Å; D422-V424 VanDerWaalsContact C-N 3.3Å; D422-V424 PolarHBondContact O-N 3.1Å; D422-V424 PolarHBondContact OD1-N 2.69Å; D422-L425 HydrophobicContact CB-CB 3.87Å; D422-L425 PolarHBondContact OD1-N 3.16Å; D422-L426 VanDerWaalsContact O-CB 3.3Å; D422-L426 WeakPolarHBondContact O-CB 3.46Å; D422-L426 PolarHBondContact O-N 3.4Å
423M84.9Confident88.1Confident61 Ų6149.7 Ų49.730%0.326%0.263SS..Hα-helixtrans-70.6-27.5-178.8-59.9-59.4173.300112.6L426 S427 V513 L572M423-L426 HydrophobicContact SD-CD2 4.18Å; M423-S427 WeakPolarHBondContact O-CB 3.32Å; M423-S427 PolarHBondContact O-N 3.42Å; M423-V513 HydrophobicContact SD-CG2 4.23Å; M423-L572 HydrophobicContact CE-CD2 3.87Å; M423-L572 HydrophobicContact SD-CD2 4.05Å
424V84.5Confident87.7Confident94 Ų9449.7 Ų49.757%0.5726%0.263SS*.Hα-helixtrans-72.7-49178.5179.70000109D422 L426 S427 Q428D422-V424 VanDerWaalsContact C-N 3.3Å; D422-V424 PolarHBondContact O-N 3.1Å; D422-V424 PolarHBondContact OD1-N 2.69Å; V424-L426 VanDerWaalsContact C-N 3.28Å; V424-L426 PolarHBondContact O-N 3.3Å; V424-S427 PolarHBondContact O-N 2.9Å; V424-Q428 WeakPolarHBondContact O-CB 3.49Å; V424-Q428 WeakPolarHBondContact O-CG 3.46Å; V424-Q428 PolarHBondContact O-N 2.96Å
425L87.2Confident87.2Confident41 Ų4151 Ų5122%0.21527%0.271CS..Hα-helixtrans-59.8-41.9174.2-177.260.9000110.8I416 M420 D422 S427 Q428 S429I416-L425 HydrophobicContact CG1-CD2 4.42Å; I416-L425 HydrophobicContact CG2-CB 4.13Å; I416-L425 HydrophobicContact CG2-CD2 4.13Å; I416-L425 HydrophobicContact CG2-CG 4.04Å; M420-L425 HydrophobicContact CE-CD2 3.76Å; D422-L425 HydrophobicContact CB-CB 3.87Å; D422-L425 PolarHBondContact OD1-N 3.16Å; L425-S427 PolarHBondContact O-N 3.46Å; L425-Q428 PolarHBondContact O-N 3.26Å; L425-S429 VanDerWaalsContact O-CB 3.3Å; L425-S429 WeakPolarHBondContact O-CB 3.34Å; L425-S429 PolarHBondContact O-N 3.15Å; L425-S429 PolarHBondContact O-OG 2.86Å
426L87.6Confident86.6Confident0 Ų051.7 Ų51.70%028%0.281CS..Hα-helixtrans-58.6-48.5176.9-178.361.1000112.1L413 I416 A417 D422 M423 V424 L430 F510 V513 L572L413-L426 HydrophobicContact CB-CD1 4.12Å; L413-L426 HydrophobicContact CD2-CD1 3.99Å; I416-L426 HydrophobicContact CB-CD1 4.37Å; I416-L426 HydrophobicContact CG2-CB 3.83Å; I416-L426 HydrophobicContact CG2-CD1 4.38Å; A417-L426 HydrophobicContact CB-CD1 4.26Å; A417-L426 HydrophobicContact CB-CD2 3.71Å; D422-L426 VanDerWaalsContact O-CB 3.3Å; D422-L426 WeakPolarHBondContact O-CB 3.46Å; D422-L426 PolarHBondContact O-N 3.4Å; M423-L426 HydrophobicContact SD-CD2 4.18Å; V424-L426 VanDerWaalsContact C-N 3.28Å; V424-L426 PolarHBondContact O-N 3.3Å; L426-L430 WeakPolarHBondContact O-CB 3.13Å; L426-L430 PolarHBondContact O-N 3.02Å; L426-F510 HydrophobicContact CD1-CD1 4.2Å; L426-F510 HydrophobicContact CD1-CE1 4.16Å; L426-F510 HydrophobicContact CD2-CD1 4.14Å; L426-V513 HydrophobicContact CB-CG1 4.34Å; L426-V513 HydrophobicContact CD2-CB 4.31Å; L426-V513 HydrophobicContact CD2-CG1 3.96Å; L426-V513 HydrophobicContact CD2-CG2 3.88Å; L426-V513 HydrophobicContact CG-CG1 4.05Å; L426-L572 HydrophobicContact CD2-CD2 4.3Å
427S86.1Confident86Confident32 Ų3253.4 Ų53.422%0.22429%0.294CS..Hα-helixtrans-62.6-44.2178.8-1720000111.6M423 V424 L425 L430 A431M423-S427 WeakPolarHBondContact O-CB 3.32Å; M423-S427 PolarHBondContact O-N 3.42Å; V424-S427 PolarHBondContact O-N 2.9Å; L425-S427 PolarHBondContact O-N 3.46Å; S427-L430 PolarHBondContact O-N 3.39Å; S427-A431 WeakPolarHBondContact O-CB 3.4Å; S427-A431 PolarHBondContact O-N 3.17Å
428Q84.8Confident85.6Confident115 Ų11554.3 Ų54.354%0.53730%0.298SS..Hα-helixtrans-64.3-50.4177-71.4178.1-100111.9V424 L425 L430 A431 T432V424-Q428 WeakPolarHBondContact O-CB 3.49Å; V424-Q428 WeakPolarHBondContact O-CG 3.46Å; V424-Q428 PolarHBondContact O-N 2.96Å; L425-Q428 PolarHBondContact O-N 3.26Å; Q428-L430 VanDerWaalsContact C-N 3.31Å; Q428-L430 PolarHBondContact O-N 3.25Å; Q428-A431 PolarHBondContact O-N 3.41Å; Q428-T432 WeakPolarHBondContact O-CB 3.05Å; Q428-T432 PolarHBondContact O-N 2.8Å; Q428-T432 PolarHBondContact O-OG1 2.9Å
429S85.6Confident85.1Confident25 Ų2556.8 Ų56.818%0.17531%0.313CS..Hα-helixtrans-59.5-42.4177.9-63.70000111.6L425 L433L425-S429 VanDerWaalsContact O-CB 3.3Å; L425-S429 WeakPolarHBondContact O-CB 3.34Å; L425-S429 PolarHBondContact O-N 3.15Å; L425-S429 PolarHBondContact O-OG 2.86Å; S429-L433 VanDerWaalsContact O-CB 3.29Å; S429-L433 WeakPolarHBondContact O-CB 3.35Å; S429-L433 WeakPolarHBondContact O-CG 3.3Å; S429-L433 PolarHBondContact O-N 2.85Å
430L86.1Confident84.4Confident1 Ų157.2 Ų57.21%0.00531%0.311CS..Hα-helixtrans-63.1-48176.6179.764.4000111.7L413 L426 S427 Q428 L433 L434 Y506 F510 Y514L413-L430 HydrophobicContact CD1-CD1 4.07Å; L426-L430 WeakPolarHBondContact O-CB 3.13Å; L426-L430 PolarHBondContact O-N 3.02Å; S427-L430 PolarHBondContact O-N 3.39Å; Q428-L430 VanDerWaalsContact C-N 3.31Å; Q428-L430 PolarHBondContact O-N 3.25Å; L430-L433 PolarHBondContact O-N 3.46Å; L430-L434 VanDerWaalsContact O-CB 3.29Å; L430-L434 WeakPolarHBondContact O-CB 3.3Å; L430-L434 PolarHBondContact O-N 3.09Å; L430-Y506 HydrophobicContact CD1-CD1 3.34Å; L430-Y506 HydrophobicContact CD1-CE1 4.12Å; L430-Y506 HydrophobicContact CD1-CG 4.09Å; L430-F510 HydrophobicContact CD1-CD2 4.31Å; L430-F510 HydrophobicContact CD2-CB 3.61Å; L430-F510 HydrophobicContact CD2-CG 4.32Å; L430-Y514 HydrophobicContact CD2-CD1 4.14Å; L430-Y514 HydrophobicContact CD2-CG 4.22Å; L430-Y514 HydrophobicContact CG-CD1 4.33Å
431A85.3Confident84Confident15 Ų1555.8 Ų55.812%0.12431%0.305CS..Hα-helixtrans-62.4-4517800000111.5S427 Q428 L434 I435 Y514S427-A431 WeakPolarHBondContact O-CB 3.4Å; S427-A431 PolarHBondContact O-N 3.17Å; Q428-A431 PolarHBondContact O-N 3.41Å; A431-L434 PolarHBondContact O-N 2.77Å; A431-I435 VanDerWaalsContact O-CB 3.28Å; A431-I435 WeakPolarHBondContact O-CB 3.4Å; A431-I435 WeakPolarHBondContact O-CD1 3.44Å; A431-I435 WeakPolarHBondContact O-CG1 3.25Å; A431-I435 PolarHBondContact O-N 2.95Å; A431-Y514 HydrophobicContact CB-CE1 4.1Å; A431-Y514 HydrophobicContact CB-CE2 4.2Å
432T83.2Confident83.6Confident85 Ų8553 Ų5352%0.52129%0.292SS..Hα-helixtrans-62.3-49.6176.9-59.80000111.3Q428 L434 I435 T436Q428-T432 WeakPolarHBondContact O-CB 3.05Å; Q428-T432 PolarHBondContact O-N 2.8Å; Q428-T432 PolarHBondContact O-OG1 2.9Å; T432-L434 PolarHBondContact O-N 3.35Å; T432-I435 PolarHBondContact O-N 2.98Å; T432-T436 WeakPolarHBondContact O-CB 3.29Å; T432-T436 PolarHBondContact O-N 3.36Å; T432-T436 PolarHBondContact O-OG1 3.3Å
433L81.8Confident83.3Confident69 Ų6954.5 Ų54.536%0.36130%0.295SS..Hα-helixtrans-59.8-46.5178.6-75172000111.5L413 S429 L430 S437L413-L433 HydrophobicContact CD1-CD1 4.36Å; L413-L433 HydrophobicContact CD2-CD1 4.04Å; L413-L433 HydrophobicContact CG-CD1 4.29Å; S429-L433 VanDerWaalsContact O-CB 3.29Å; S429-L433 WeakPolarHBondContact O-CB 3.35Å; S429-L433 WeakPolarHBondContact O-CG 3.3Å; S429-L433 PolarHBondContact O-N 2.85Å; L430-L433 PolarHBondContact O-N 3.46Å; L433-S437 WeakPolarHBondContact O-CB 3.47Å; L433-S437 PolarHBondContact O-N 2.78Å
434L83.3Confident83Confident1 Ų156.9 Ų56.91%0.00531%0.307CS..Hα-helixtrans-63.4-52.4-179.5-163.888.6000111.1L430 A431 T432 Q438 L503 Y506 L520 V521L430-L434 VanDerWaalsContact O-CB 3.29Å; L430-L434 WeakPolarHBondContact O-CB 3.3Å; L430-L434 PolarHBondContact O-N 3.09Å; A431-L434 PolarHBondContact O-N 2.77Å; T432-L434 PolarHBondContact O-N 3.35Å; L434-Q438 WeakPolarHBondContact O-CB 3.2Å; L434-Q438 WeakPolarHBondContact O-CG 3.35Å; L434-Q438 PolarHBondContact O-N 3.47Å; L434-Q438 PolarHBondContact O-NE2 3.34Å; L434-L503 HydrophobicContact CD1-CD2 4.05Å; L434-Y506 HydrophobicContact CD1-CD2 3.54Å; L434-Y506 HydrophobicContact CD1-CE2 4.34Å; L434-Y506 HydrophobicContact CD1-CG 3.78Å; L434-L520 HydrophobicContact CD2-CB 3.47Å; L434-L520 VanDerWaalsContact CD2-CB 3.47Å; L434-L520 HydrophobicContact CD2-CD1 3.63Å; L434-L520 HydrophobicContact CD2-CG 4.18Å; L434-V521 HydrophobicContact CD1-CG2 4.19Å; L434-V521 HydrophobicContact CD2-CG2 4.41Å
435I84.6Confident82.5Confident71 Ų7154.5 Ų54.536%0.36429%0.29SS..Hα-helixtrans-65.7-48.1-176.8-66.4167.5000110.8A431 T432 Q438 I439 L520A431-I435 VanDerWaalsContact O-CB 3.28Å; A431-I435 WeakPolarHBondContact O-CB 3.4Å; A431-I435 WeakPolarHBondContact O-CD1 3.44Å; A431-I435 WeakPolarHBondContact O-CG1 3.25Å; A431-I435 PolarHBondContact O-N 2.95Å; T432-I435 PolarHBondContact O-N 2.98Å; I435-Q438 PolarHBondContact O-N 2.97Å; I435-I439 HydrophobicContact CG2-CD1 3.69Å; I435-I439 HydrophobicContact CG2-CG1 4.45Å; I435-I439 WeakPolarHBondContact O-CB 3.15Å; I435-I439 VanDerWaalsContact O-CG1 3.27Å; I435-I439 WeakPolarHBondContact O-CG1 3.38Å; I435-I439 PolarHBondContact O-N 3.01Å; I435-L520 HydrophobicContact CD1-CD1 4.25Å; I435-L520 HydrophobicContact CG1-CD1 3.88Å
436T80.6Confident81.7Confident70 Ų7053.7 Ų53.743%0.42929%0.29SS..Hα-helixtrans-65.3-44.3-178.7-600000110.9T432 I439 L440T432-T436 WeakPolarHBondContact O-CB 3.29Å; T432-T436 PolarHBondContact O-N 3.36Å; T432-T436 PolarHBondContact O-OG1 3.3Å; T436-I439 PolarHBondContact O-N 3.43Å; T436-L440 HydrophobicContact CG2-CD1 3.87Å; T436-L440 HydrophobicContact CG2-CG 4.4Å; T436-L440 WeakPolarHBondContact O-CB 3.06Å; T436-L440 VanDerWaalsContact O-CG 3.27Å; T436-L440 WeakPolarHBondContact O-CG 3.1Å; T436-L440 PolarHBondContact O-N 3.04Å
437S78.4Confident81.1Confident41 Ų4159.2 Ų59.229%0.28731%0.314SS..Hα-helixtrans-62.5-44.6176.1-173.40000111.4L433 I439 L440 N441L433-S437 WeakPolarHBondContact O-CB 3.47Å; L433-S437 PolarHBondContact O-N 2.78Å; S437-I439 PolarHBondContact O-N 3.25Å; S437-L440 PolarHBondContact O-N 3.05Å; S437-N441 VanDerWaalsContact O-CB 3.27Å; S437-N441 WeakPolarHBondContact O-CB 3.3Å; S437-N441 PolarHBondContact O-N 3.3Å; S437-N441 PolarHBondContact O-ND2 3.45Å; S437-N441 PolarHBondContact O-OD1 3.24Å; S437-N441 PolarHBondContact OG-ND2 2.99Å
438Q82.4Confident80.8Confident19 Ų1960.1 Ų60.19%0.08932%0.316CS..Hα-helixtrans-63.8-42.4179.4-70.4-15.3-66.500112.2L434 I435 Q442 L503 N524L434-Q438 WeakPolarHBondContact O-CB 3.2Å; L434-Q438 WeakPolarHBondContact O-CG 3.35Å; L434-Q438 PolarHBondContact O-N 3.47Å; L434-Q438 PolarHBondContact O-NE2 3.34Å; I435-Q438 PolarHBondContact O-N 2.97Å; Q438-Q442 VanDerWaalsContact O-CB 3.23Å; Q438-Q442 WeakPolarHBondContact O-CB 3.31Å; Q438-Q442 PolarHBondContact O-N 2.81Å; Q438-L503 VanDerWaalsContact NE2-CD2 3.29Å; Q438-N524 HydrophobicContact CG-CB 4.16Å; Q438-N524 PolarHBondContact OE1-ND2 2.91Å; Q438-N524 VanDerWaalsContact OE1-ND2 3.13Å; Q438-N524 PolarHBondContact OE1-OD1 3.38Å; Q438-N524 VanDerWaalsContact OE1-OD1 3.08Å
439I81.7Confident80.3Confident113 Ų11355.8 Ų55.858%0.57930%0.297SS*.Hα-helixtrans-64.3-44.2177.9-70170.4000110.9I435 T436 S437 F443I435-I439 HydrophobicContact CG2-CD1 3.69Å; I435-I439 HydrophobicContact CG2-CG1 4.45Å; I435-I439 WeakPolarHBondContact O-CB 3.15Å; I435-I439 VanDerWaalsContact O-CG1 3.27Å; I435-I439 WeakPolarHBondContact O-CG1 3.38Å; I435-I439 PolarHBondContact O-N 3.01Å; T436-I439 PolarHBondContact O-N 3.43Å; S437-I439 PolarHBondContact O-N 3.25Å; I439-F443 WeakPolarHBondContact O-CB 3.4Å; I439-F443 PolarHBondContact O-N 2.77Å
440L79.4Confident79.7Confident102 Ų10259.5 Ų59.553%0.53431%0.308SS..Hα-helixtrans-66-45.2179.2-72.1174.4000111.5T436 S437 F443 M444T436-L440 HydrophobicContact CG2-CD1 3.87Å; T436-L440 HydrophobicContact CG2-CG 4.4Å; T436-L440 WeakPolarHBondContact O-CB 3.06Å; T436-L440 VanDerWaalsContact O-CG 3.27Å; T436-L440 WeakPolarHBondContact O-CG 3.1Å; T436-L440 PolarHBondContact O-N 3.04Å; S437-L440 PolarHBondContact O-N 3.05Å; L440-F443 PolarHBondContact O-N 2.74Å; L440-M444 WeakPolarHBondContact O-CB 3.49Å; L440-M444 WeakPolarHBondContact O-CG 3.29Å; L440-M444 PolarHBondContact O-N 2.78Å
441N79.4Confident79.4Confident45 Ų4565.2 Ų65.224%0.24133%0.33CS..Hα-helixtrans-61.3-51.1177-70.1-5.6000110.1S437 F443 M444 E445S437-N441 VanDerWaalsContact O-CB 3.27Å; S437-N441 WeakPolarHBondContact O-CB 3.3Å; S437-N441 PolarHBondContact O-N 3.3Å; S437-N441 PolarHBondContact O-ND2 3.45Å; S437-N441 PolarHBondContact O-OD1 3.24Å; S437-N441 PolarHBondContact OG-ND2 2.99Å; N441-F443 PolarHBondContact O-N 2.91Å; N441-F443 VanDerWaalsContact O-N 3.14Å; N441-M444 CarbonylContact O-C 3.4Å; N441-M444 PolarHBondContact O-N 2.96Å; N441-E445 VanDerWaalsContact O-CB 3.24Å; N441-E445 WeakPolarHBondContact O-CB 2.93Å; N441-E445 VanDerWaalsContact O-CG 3.28Å; N441-E445 WeakPolarHBondContact O-CG 3.48Å; N441-E445 PolarHBondContact O-N 2.7Å
442Q80.6Confident79.1Confident44 Ų4468.5 Ų68.521%0.20635%0.345CS..Hα-helixtrans-58.2-36.6178.9-166.470.683.500112.5Q438 A446 F447 T527Q438-Q442 VanDerWaalsContact O-CB 3.23Å; Q438-Q442 WeakPolarHBondContact O-CB 3.31Å; Q438-Q442 PolarHBondContact O-N 2.81Å; Q442-A446 WeakPolarHBondContact O-CB 3.17Å; Q442-A446 PolarHBondContact O-N 3.3Å; Q442-F447 PolarHBondContact O-N 2.97Å; Q442-T527 PolarHBondContact OE1-OG1 2.9Å
443F82.4Confident78.5Confident100 Ų10065.7 Ų65.744%0.43933%0.326SS..Iπ-helixtrans-66.5-48.3174.6180-94.7000112.1I439 L440 N441 E445 F447 L448I439-F443 WeakPolarHBondContact O-CB 3.4Å; I439-F443 PolarHBondContact O-N 2.77Å; L440-F443 PolarHBondContact O-N 2.74Å; N441-F443 PolarHBondContact O-N 2.91Å; N441-F443 VanDerWaalsContact O-N 3.14Å; F443-E445 VanDerWaalsContact C-N 3.31Å; F443-E445 PolarHBondContact O-N 3.31Å; F443-F447 HydrophobicContact CD2-CB 4.04Å; F443-F447 AromaticContact CD2-CD1 3.63Å; F443-F447 HydrophobicContact CD2-CD1 3.63Å; F443-F447 HydrophobicContact CD2-CE1 4.41Å; F443-F447 HydrophobicContact CD2-CG 4.07Å; F443-F447 AromaticContact CE2-CD1 3.23Å; F443-F447 HydrophobicContact CE2-CD1 3.23Å; F443-F447 AromaticContact CE2-CE1 3.66Å; F443-F447 HydrophobicContact CE2-CE1 3.66Å; F443-F447 HydrophobicContact CE2-CG 4.11Å; F443-F447 AromaticContact CZ-CD1 3.97Å; F443-F447 HydrophobicContact CZ-CD1 3.97Å; F443-F447 HydrophobicContact CZ-CE1 4.33Å; F443-F447 PolarHBondContact O-N 2.84Å; F443-L448 HydrophobicContact CE1-CB 4.48Å; F443-L448 WeakPolarHBondContact O-CB 3.46Å; F443-L448 PolarHBondContact O-N 2.97Å
444M78.7Confident78.1Confident112 Ų11270.1 Ų70.155%0.55234%0.338SS*.Iπ-helixtrans-69.7-28.9-178.6-69.7-62.3-80.400112.7L440 N441 L448 P449L440-M444 WeakPolarHBondContact O-CB 3.49Å; L440-M444 WeakPolarHBondContact O-CG 3.29Å; L440-M444 PolarHBondContact O-N 2.78Å; N441-M444 CarbonylContact O-C 3.4Å; N441-M444 PolarHBondContact O-N 2.96Å; M444-L448 HydrophobicContact CE-CD2 4.23Å; M444-L448 HydrophobicContact SD-CD2 3.82Å; M444-P449 WeakPolarHBondContact O-CD 3.15Å; M444-P449 WeakPolarHBondContact O-CG 3.36Å
445E73Confident77.8Confident43 Ų4376.5 Ų76.520%0.20136%0.362CS..Iπ-helixtrans-99.5-38.9-172.1-66.2-165.6-167.800114N441 F443 P449 K535N441-E445 VanDerWaalsContact O-CB 3.24Å; N441-E445 WeakPolarHBondContact O-CB 2.93Å; N441-E445 VanDerWaalsContact O-CG 3.28Å; N441-E445 WeakPolarHBondContact O-CG 3.48Å; N441-E445 PolarHBondContact O-N 2.7Å; F443-E445 VanDerWaalsContact C-N 3.31Å; F443-E445 PolarHBondContact O-N 3.31Å; E445-P449 WeakPolarHBondContact O-CG 3.35Å; E445-K535 HydrophobicContact CB-CD 4.33Å; E445-K535 WeakPolarHBondContact O-CD 3.45Å; E445-K535 WeakPolarHBondContact O-CG 3.37Å; E445-K535 IonicContact OE2-NZ 2.8Å; E445-K535 PolarHBondContact OE2-NZ 3.35Å
446A70.1Confident77.1Confident25 Ų2576.8 Ų76.821%0.20736%0.358CS..Iπ-helixtrans-100.8-54.7179.300000111.9Q442 Y450Q442-A446 WeakPolarHBondContact O-CB 3.17Å; Q442-A446 PolarHBondContact O-N 3.3Å; A446-Y450 WeakPolarHBondContact O-CB 3.38Å; A446-Y450 PolarHBondContact O-N 2.93Å
447F75.3Confident76.5Confident115 Ų11576.6 Ų76.650%0.50436%0.355SS..Iπ-helixtrans-73.3-50.8-167.5-177.2-93.8000112.6Q442 F443 Y450 W451Q442-F447 PolarHBondContact O-N 2.97Å; F443-F447 HydrophobicContact CD2-CB 4.04Å; F443-F447 AromaticContact CD2-CD1 3.63Å; F443-F447 HydrophobicContact CD2-CD1 3.63Å; F443-F447 HydrophobicContact CD2-CE1 4.41Å; F443-F447 HydrophobicContact CD2-CG 4.07Å; F443-F447 AromaticContact CE2-CD1 3.23Å; F443-F447 HydrophobicContact CE2-CD1 3.23Å; F443-F447 AromaticContact CE2-CE1 3.66Å; F443-F447 HydrophobicContact CE2-CE1 3.66Å; F443-F447 HydrophobicContact CE2-CG 4.11Å; F443-F447 AromaticContact CZ-CD1 3.97Å; F443-F447 HydrophobicContact CZ-CD1 3.97Å; F443-F447 HydrophobicContact CZ-CE1 4.33Å; F443-F447 PolarHBondContact O-N 2.84Å; F447-Y450 PolarHBondContact O-N 3.25Å; F447-W451 VanDerWaalsContact O-CB 3.31Å; F447-W451 WeakPolarHBondContact O-CB 3.49Å; F447-W451 PolarHBondContact O-N 3.15Å
448L80.9Confident76.1Confident52 Ų5280.5 Ų80.527%0.27237%0.367SS..Hα-helixtrans-62.7-48.5-176.9177.567.3000111.7F443 M444 W451 L452F443-L448 HydrophobicContact CE1-CB 4.48Å; F443-L448 WeakPolarHBondContact O-CB 3.46Å; F443-L448 PolarHBondContact O-N 2.97Å; M444-L448 HydrophobicContact CE-CD2 4.23Å; M444-L448 HydrophobicContact SD-CD2 3.82Å; L448-W451 PolarHBondContact O-N 3.05Å; L448-L452 HydrophobicContact CD1-CD1 3.97Å; L448-L452 HydrophobicContact CD1-CG 4.08Å; L448-L452 HydrophobicContact CG-CD1 3.96Å; L448-L452 HydrophobicContact CG-CG 4.44Å; L448-L452 WeakPolarHBondContact O-CB 3.35Å; L448-L452 VanDerWaalsContact O-CG 3.3Å; L448-L452 WeakPolarHBondContact O-CG 2.92Å; L448-L452 PolarHBondContact O-N 3.15Å
449P74.4Confident75.4Confident23 Ų2385.5 Ų85.515%0.14939%0.388CS..Hα-helixtrans-66.6-41178.6-23.838.6000111.8M444 E445 W451 L452 Q453 V539M444-P449 WeakPolarHBondContact O-CD 3.15Å; M444-P449 WeakPolarHBondContact O-CG 3.36Å; E445-P449 WeakPolarHBondContact O-CG 3.35Å; P449-W451 VanDerWaalsContact C-N 3.33Å; P449-W451 PolarHBondContact O-N 3.37Å; P449-L452 PolarHBondContact O-N 3.31Å; P449-Q453 WeakPolarHBondContact O-CB 3.17Å; P449-Q453 PolarHBondContact O-N 3.24Å; P449-V539 HydrophobicContact CB-CB 4.47Å; P449-V539 HydrophobicContact CB-CG1 3.98Å; P449-V539 HydrophobicContact CB-CG2 3.64Å
450Y73.3Confident74.5Confident103 Ų10382 Ų8240%0.40437%0.37SS..Hα-helixtrans-57.4-45.7173.9175.6-89.8000111.8A446 F447 R454 F534A446-Y450 WeakPolarHBondContact O-CB 3.38Å; A446-Y450 PolarHBondContact O-N 2.93Å; F447-Y450 PolarHBondContact O-N 3.25Å; Y450-R454 VanDerWaalsContact O-CB 3.25Å; Y450-R454 WeakPolarHBondContact O-CB 3.37Å; Y450-R454 PolarHBondContact O-N 2.87Å; Y450-F534 AromaticContact CD2-CE1 3.86Å; Y450-F534 HydrophobicContact CD2-CE1 3.86Å; Y450-F534 AromaticContact CD2-CE2 3.75Å; Y450-F534 HydrophobicContact CD2-CE2 3.75Å; Y450-F534 AromaticContact CD2-CZ 3.36Å; Y450-F534 HydrophobicContact CD2-CZ 3.36Å; Y450-F534 HydrophobicContact CE2-CE2 4.21Å; Y450-F534 HydrophobicContact CE2-CZ 4.16Å; Y450-F534 HydrophobicContact CG-CE1 4.36Å; Y450-F534 HydrophobicContact CG-CZ 4.2Å
451W78.9Confident73.7Confident122 Ų12281.7 Ų81.746%0.46237%0.368SS..Hα-helixtrans-66.9-46.7180179.883.9000112.2F447 L448 P449 R454 R455F447-W451 VanDerWaalsContact O-CB 3.31Å; F447-W451 WeakPolarHBondContact O-CB 3.49Å; F447-W451 PolarHBondContact O-N 3.15Å; L448-W451 PolarHBondContact O-N 3.05Å; P449-W451 VanDerWaalsContact C-N 3.33Å; P449-W451 PolarHBondContact O-N 3.37Å; W451-R454 PolarHBondContact O-N 3.43Å; W451-R455 WeakPolarHBondContact O-CB 3.45Å; W451-R455 PolarHBondContact O-N 2.93Å
452L77.8Confident73.1Confident84 Ų8486.9 Ų86.944%0.4438%0.384SS..Hα-helixtrans-60.7-45.1176-72.2175.5000111.1L448 P449 R455 R456L448-L452 HydrophobicContact CD1-CD1 3.97Å; L448-L452 HydrophobicContact CD1-CG 4.08Å; L448-L452 HydrophobicContact CG-CD1 3.96Å; L448-L452 HydrophobicContact CG-CG 4.44Å; L448-L452 WeakPolarHBondContact O-CB 3.35Å; L448-L452 VanDerWaalsContact O-CG 3.3Å; L448-L452 WeakPolarHBondContact O-CG 2.92Å; L448-L452 PolarHBondContact O-N 3.15Å; P449-L452 PolarHBondContact O-N 3.31Å; L452-R455 PolarHBondContact O-N 3.46Å; L452-R456 WeakPolarHBondContact O-CB 3.49Å; L452-R456 PolarHBondContact O-N 3.34Å
453Q70.9Confident72.2Confident25 Ų2590.3 Ų90.312%0.11740%0.398CS..Hα-helixtrans-63-44.8177.6-174.463.60.900111.3P449 R455 R456 N457 H538P449-Q453 WeakPolarHBondContact O-CB 3.17Å; P449-Q453 PolarHBondContact O-N 3.24Å; Q453-R455 VanDerWaalsContact C-N 3.31Å; Q453-R455 PolarHBondContact O-N 2.9Å; Q453-R456 PolarHBondContact O-N 2.83Å; Q453-N457 WeakPolarHBondContact O-CB 3.48Å; Q453-N457 PolarHBondContact O-N 3.13Å; Q453-H538 HydrophobicContact CG-CB 4.42Å; Q453-H538 PolarHBondContact NE2-O 2.89Å; Q453-H538 PolarHBondContact OE1-O 2.94Å
454R74.2Confident71.1Confident163 Ų16386.4 Ų86.462%0.61538%0.382SS*.Hα-helixtrans-61.7-39.7175.9-171.6171.9-177.2177.8-1.4111.7Y450 W451 K458Y450-R454 VanDerWaalsContact O-CB 3.25Å; Y450-R454 WeakPolarHBondContact O-CB 3.37Å; Y450-R454 PolarHBondContact O-N 2.87Å; W451-R454 PolarHBondContact O-N 3.43Å; R454-K458 VanDerWaalsContact O-CB 3.29Å; R454-K458 WeakPolarHBondContact O-CB 3.5Å; R454-K458 PolarHBondContact O-N 2.8Å
455R77.7Confident70.2Confident135 Ų13587.5 Ų87.551%0.50939%0.386SS..Hα-helixtrans-66.5-41175.5-167.4178.2-178.1-168.20.3111.5W451 L452 Q453 K459W451-R455 WeakPolarHBondContact O-CB 3.45Å; W451-R455 PolarHBondContact O-N 2.93Å; L452-R455 PolarHBondContact O-N 3.46Å; Q453-R455 VanDerWaalsContact C-N 3.31Å; Q453-R455 PolarHBondContact O-N 2.9Å; R455-K459 WeakPolarHBondContact O-CG 3.49Å; R455-K459 PolarHBondContact O-N 3.16Å; R455-K459 VanDerWaalsContact O-N 3.09Å
456R69.6Low69.6Low77 Ų7794.5 Ų94.529%0.29142%0.416SS..Hα-helixtrans-66-50.1176.8-171.9175.6176.4165.8-3.8111.8L452 Q453 K458 K459 M460 L483 D486L452-R456 WeakPolarHBondContact O-CB 3.49Å; L452-R456 PolarHBondContact O-N 3.34Å; Q453-R456 PolarHBondContact O-N 2.83Å; R456-K458 VanDerWaalsContact C-N 3.31Å; R456-K458 PolarHBondContact O-N 3.32Å; R456-K459 WeakPolarHBondContact O-CB 3.38Å; R456-K459 PolarHBondContact O-N 3.01Å; R456-M460 WeakPolarHBondContact O-CG 3.42Å; R456-M460 PolarHBondContact O-N 3.26Å; R456-L483 PolarHBondContact NH2-O 3.33Å; R456-D486 PolarHBondContact NH1-O 2.52Å; R456-D486 PolarHBondContact NH2-O 2.68Å
457N66.5Low68.9Low66 Ų6698 Ų9835%0.35343%0.427SS..Hα-helixtrans-58.8-40.5175-75.8-12.3000111.8Q453 K459 M460 I461Q453-N457 WeakPolarHBondContact O-CB 3.48Å; Q453-N457 PolarHBondContact O-N 3.13Å; N457-K459 PolarHBondContact O-N 3.41Å; N457-M460 PolarHBondContact O-N 2.97Å; N457-I461 VanDerWaalsContact O-CB 3.3Å; N457-I461 WeakPolarHBondContact O-CB 3.47Å; N457-I461 WeakPolarHBondContact O-CG1 3.31Å; N457-I461 PolarHBondContact O-N 3.39Å
458K70.2Confident67.8Low123 Ų12398.3 Ų98.354%0.53542%0.424SS..Hα-helixtrans-65.1-36.8175.3-165.7174.5-174177.20112.5R454 R456 R462R454-K458 VanDerWaalsContact O-CB 3.29Å; R454-K458 WeakPolarHBondContact O-CB 3.5Å; R454-K458 PolarHBondContact O-N 2.8Å; R456-K458 VanDerWaalsContact C-N 3.31Å; R456-K458 PolarHBondContact O-N 3.32Å; K458-R462 WeakPolarHBondContact O-CB 3.44Å; K458-R462 WeakPolarHBondContact O-CD 3.49Å; K458-R462 WeakPolarHBondContact O-CG 3.26Å; K458-R462 PolarHBondContact O-N 2.76Å
459K69.2Low66.4Low123 Ų123100.7 Ų100.754%0.53544%0.441SS..Hα-helixtrans-68.1-42.6173.2-75.3-179.3-179.7-178.40111.6R455 R456 N457 R462 K463R455-K459 WeakPolarHBondContact O-CG 3.49Å; R455-K459 PolarHBondContact O-N 3.16Å; R455-K459 VanDerWaalsContact O-N 3.09Å; R456-K459 WeakPolarHBondContact O-CB 3.38Å; R456-K459 PolarHBondContact O-N 3.01Å; N457-K459 PolarHBondContact O-N 3.41Å; K459-R462 PolarHBondContact O-N 3.2Å; K459-K463 WeakPolarHBondContact O-CG 3.27Å; K459-K463 PolarHBondContact O-N 2.94Å
460M61.7Low64.7Low41 Ų41106.1 Ų106.120%0.20248%0.476CS..Hα-helixtrans-68.2-48.9179.6-72.3-55.9-54.700112.2R456 N457 R462 K463 V464 L483R456-M460 WeakPolarHBondContact O-CG 3.42Å; R456-M460 PolarHBondContact O-N 3.26Å; N457-M460 PolarHBondContact O-N 2.97Å; M460-R462 PolarHBondContact O-N 2.95Å; M460-K463 CarbonylContact O-C 3.6Å; M460-K463 WeakPolarHBondContact O-CA 3.46Å; M460-K463 WeakPolarHBondContact O-CB 3.23Å; M460-K463 PolarHBondContact O-N 3.44Å; M460-K463 HydrophobicContact SD-CD 4.41Å; M460-V464 WeakPolarHBondContact O-CB 3.48Å; M460-V464 VanDerWaalsContact O-CG2 3.23Å; M460-V464 WeakPolarHBondContact O-CG2 3.21Å; M460-V464 PolarHBondContact O-N 3.01Å; M460-L483 HydrophobicContact CB-CD2 4.5Å; M460-L483 HydrophobicContact CE-CD1 4.28Å; M460-L483 HydrophobicContact CE-CD2 3.45Å; M460-L483 VanDerWaalsContact CE-CD2 3.45Å; M460-L483 HydrophobicContact CE-CG 3.97Å; M460-L483 HydrophobicContact CG-CD2 3.7Å; M460-L483 HydrophobicContact SD-CD2 3.86Å
461I63.5Low63.5Low95 Ų95104.4 Ų104.449%0.48749%0.49SS..Hα-helixtrans-56.2-39.6174.7-69.1166.4000110.7N457 Q465N457-I461 VanDerWaalsContact O-CB 3.3Å; N457-I461 WeakPolarHBondContact O-CB 3.47Å; N457-I461 WeakPolarHBondContact O-CG1 3.31Å; N457-I461 PolarHBondContact O-N 3.39Å; I461-Q465 HydrophobicContact CG2-CG 4.2Å; I461-Q465 WeakPolarHBondContact O-CB 3.28Å; I461-Q465 WeakPolarHBondContact O-CG 3.21Å; I461-Q465 PolarHBondContact O-N 3.38Å
462R66.2Low62.1Low154 Ų154103.6 Ų103.658%0.58150%0.495SS*.Hα-helixtrans-65.2-39.5174-76.7172.3176-175.5-5.5112.9K458 K459 M460 K466K458-R462 WeakPolarHBondContact O-CB 3.44Å; K458-R462 WeakPolarHBondContact O-CD 3.49Å; K458-R462 WeakPolarHBondContact O-CG 3.26Å; K458-R462 PolarHBondContact O-N 2.76Å; K459-R462 PolarHBondContact O-N 3.2Å; M460-R462 PolarHBondContact O-N 2.95Å; R462-K466 VanDerWaalsContact O-CB 3.29Å; R462-K466 WeakPolarHBondContact O-CB 3.09Å; R462-K466 PolarHBondContact O-N 3.26Å
463K62.2Low60.8Low116 Ų116109.1 Ų109.150%0.50452%0.515SS..Hα-helixtrans-67.7-44.5175.5-76.6-174.7175.7-169.90111.6K459 M460 K466 K467K459-K463 WeakPolarHBondContact O-CG 3.27Å; K459-K463 PolarHBondContact O-N 2.94Å; M460-K463 CarbonylContact O-C 3.6Å; M460-K463 WeakPolarHBondContact O-CA 3.46Å; M460-K463 WeakPolarHBondContact O-CB 3.23Å; M460-K463 PolarHBondContact O-N 3.44Å; M460-K463 HydrophobicContact SD-CD 4.41Å; K463-K466 PolarHBondContact O-N 2.75Å; K463-K467 WeakPolarHBondContact O-CG 3.13Å; K463-K467 PolarHBondContact O-N 3.04Å
464V57.9Low60.1Low18 Ų18114.4 Ų114.411%0.10954%0.54CS..Hα-helixtrans-65-49.4177.7174.40000111M460 K466 K467 R468 L475 E479M460-V464 WeakPolarHBondContact O-CB 3.48Å; M460-V464 VanDerWaalsContact O-CG2 3.23Å; M460-V464 WeakPolarHBondContact O-CG2 3.21Å; M460-V464 PolarHBondContact O-N 3.01Å; V464-K466 VanDerWaalsContact C-N 3.27Å; V464-K466 PolarHBondContact O-N 3.22Å; V464-K467 CarbonylContact O-C 3.58Å; V464-K467 WeakPolarHBondContact O-CA 3.45Å; V464-K467 PolarHBondContact O-N 3.02Å; V464-R468 HydrophobicContact CG1-CG 4.1Å; V464-R468 WeakPolarHBondContact O-CB 3.4Å; V464-R468 PolarHBondContact O-N 2.95Å; V464-L475 HydrophobicContact CB-CD2 4.39Å; V464-L475 HydrophobicContact CG1-CD2 3.76Å; V464-L475 HydrophobicContact CG2-CD2 3.65Å; V464-E479 WeakPolarHBondContact CG2-OE1 3.35Å
465Q61.2Low59.6Low134 Ų134109 Ų10963%0.62652%0.523SS*.Hα-helixtrans-62.6-33.6178.9-82.5177.8-33.900112.5I461 K467I461-Q465 HydrophobicContact CG2-CG 4.2Å; I461-Q465 WeakPolarHBondContact O-CB 3.28Å; I461-Q465 WeakPolarHBondContact O-CG 3.21Å; I461-Q465 PolarHBondContact O-N 3.38Å; Q465-K467 PolarHBondContact O-N 2.91Å
466K59Low59.5Low191 Ų191105.3 Ų105.383%0.8352%0.516SS*.THydrogen-bonded Turntrans-70-17.9174.8-163.1176.4-177.6-175.60112.7R462 K463 V464R462-K466 VanDerWaalsContact O-CB 3.29Å; R462-K466 WeakPolarHBondContact O-CB 3.09Å; R462-K466 PolarHBondContact O-N 3.26Å; K463-K466 PolarHBondContact O-N 2.75Å; V464-K466 VanDerWaalsContact C-N 3.27Å; V464-K466 PolarHBondContact O-N 3.22Å
467K56.7Low60.1Low99 Ų99104 Ų10443%0.4352%0.515SS..THydrogen-bonded Turntrans-117.6-1.6-174.5-66.5-178.1176.3-1700113.8E59 K463 V464 Q465E59-K467 IonicContact OE1-NZ 3.43Å; E59-K467 PolarHBondContact OE1-NZ 3.46Å; K463-K467 WeakPolarHBondContact O-CG 3.13Å; K463-K467 PolarHBondContact O-N 3.04Å; V464-K467 CarbonylContact O-C 3.58Å; V464-K467 WeakPolarHBondContact O-CA 3.45Å; V464-K467 PolarHBondContact O-N 3.02Å; Q465-K467 PolarHBondContact O-N 2.91Å
468R51.9Low60.6Low120 Ų120101.5 Ų101.545%0.45350%0.503SS..  trans-78.2125.2179.2-107.8-176.4170.9179.8-4.1110.7V464 D472 K473 E474V464-R468 HydrophobicContact CG1-CG 4.1Å; V464-R468 WeakPolarHBondContact O-CB 3.4Å; V464-R468 PolarHBondContact O-N 2.95Å; R468-D472 VanDerWaalsContact CZ-O 3.24Å; R468-D472 PolarHBondContact NE-O 2.88Å; R468-D472 PolarHBondContact NH2-O 3.26Å; R468-D472 VanDerWaalsContact NH2-O 3.09Å; R468-K473 PolarHBondContact NH2-O 3.37Å; R468-E474 PolarHBondContact NH2-O 3.37Å
469T51.2Low61.1Low102 Ų10298.1 Ų98.163%0.62649%0.49SS*.  trans-67.8146.2155.923.60000109.5G471T469-G471 PolarHBondContact O-N 3.46Å
470P38.8Very low61.8Low138 Ų13893.3 Ų93.390%0.89647%0.469SS*.THydrogen-bonded Turntrans-73.1103.5-178.84.510.2000109.3
471G48.3Very low62.9Low67 Ų6791.4 Ų91.469%0.69146%0.459SS*.THydrogen-bonded Turntrans163.5-35.4174.700000115.8T469T469-G471 PolarHBondContact O-N 3.46Å
472D48.8Very low63.9Low105 Ų10589.2 Ų89.256%0.56145%0.445SS*.  trans-84.4122.3-172.1-75.9-26.2000113.6R468R468-D472 VanDerWaalsContact CZ-O 3.24Å; R468-D472 PolarHBondContact NE-O 2.88Å; R468-D472 PolarHBondContact NH2-O 3.26Å; R468-D472 VanDerWaalsContact NH2-O 3.09Å
473K51.6Low64.6Low200 Ų20083.7 Ų83.787%0.8743%0.427SS*.SBendtrans-74.2-28176.6-74.6178.6179.31720112.4R468R468-K473 PolarHBondContact NH2-O 3.37Å
474E56.6Low65.8Low135 Ų13578.7 Ų78.763%0.63141%0.405SS*.SBendtrans-113.9165.3-172.8-58.8-163.4157.900113.6R468R468-E474 PolarHBondContact NH2-O 3.37Å
475L63.4Low67.2Low51 Ų5178.2 Ų78.227%0.26740%0.403SS..  trans-85.3135.1171.8-73.2157000107.9V464 E479 L483V464-L475 HydrophobicContact CB-CD2 4.39Å; V464-L475 HydrophobicContact CG1-CD2 3.76Å; V464-L475 HydrophobicContact CG2-CD2 3.65Å; L475-E479 HydrophobicContact CD2-CG 4.25Å; L475-E479 WeakPolarHBondContact CD2-OE2 3.41Å; L475-L483 HydrophobicContact CD1-CD1 4.37Å
476P76Confident68.3Low56 Ų5677.5 Ų77.536%0.36440%0.404SS..  trans-53.4142.1172.2-2433.4000111.2V56 A478 E479 Q480V56-P476 HydrophobicContact CG2-CG 4.25Å; P476-A478 PolarHBondContact O-N 3.06Å; P476-A478 VanDerWaalsContact O-N 3.11Å; P476-E479 PolarHBondContact O-N 2.96Å; P476-Q480 PolarHBondContact O-N 3.45Å
477L80.3Confident69.5Low50 Ų5069.7 Ų69.726%0.26237%0.37SS..Hα-helixtrans-49.3-40.7-179.717668.8000112.5P10 P14 L68 E479 Q480 V481P10-L477 HydrophobicContact CB-CD2 4.49Å; P10-L477 HydrophobicContact CG-CD2 3.64Å; P14-L477 HydrophobicContact CG-CD1 4.06Å; P14-L477 HydrophobicContact CG-CD2 3.83Å; L68-L477 HydrophobicContact CD1-CD2 3.92Å; L477-E479 VanDerWaalsContact C-N 3.3Å; L477-E479 PolarHBondContact O-N 2.96Å; L477-Q480 WeakPolarHBondContact O-CB 3.35Å; L477-Q480 PolarHBondContact O-N 3.35Å; L477-Q480 VanDerWaalsContact O-N 3.15Å; L477-V481 HydrophobicContact CD1-CG2 4.27Å; L477-V481 HydrophobicContact CG-CG2 4.32Å; L477-V481 VanDerWaalsContact O-CG2 3.3Å; L477-V481 WeakPolarHBondContact O-CG2 3.27Å; L477-V481 PolarHBondContact O-N 3.4Å
478A78.9Confident70.8Confident13 Ų1367.7 Ų67.711%0.10737%0.369CS..Hα-helixtrans-60.4-36.6178.400000113.6L52 P476 R482L52-A478 HydrophobicContact CD1-CB 3.95Å; L52-A478 HydrophobicContact CD2-CB 4.16Å; L52-A478 HydrophobicContact CG-CB 4.12Å; P476-A478 PolarHBondContact O-N 3.06Å; P476-A478 VanDerWaalsContact O-N 3.11Å; A478-R482 WeakPolarHBondContact O-CG 3.31Å; A478-R482 PolarHBondContact O-N 3.25Å
479E78.8Confident72.5Confident53 Ų5365.6 Ų65.625%0.24837%0.37CS..Hα-helixtrans-73.8-34.6177.2-172.4167-158.700111.5V464 L475 P476 L477 L483V464-E479 WeakPolarHBondContact CG2-OE1 3.35Å; L475-E479 HydrophobicContact CD2-CG 4.25Å; L475-E479 WeakPolarHBondContact CD2-OE2 3.41Å; P476-E479 PolarHBondContact O-N 2.96Å; L477-E479 VanDerWaalsContact C-N 3.3Å; L477-E479 PolarHBondContact O-N 2.96Å; E479-L483 HydrophobicContact CG-CD1 4.27Å; E479-L483 VanDerWaalsContact O-CB 3.31Å; E479-L483 WeakPolarHBondContact O-CB 3.46Å; E479-L483 VanDerWaalsContact O-CG 3.27Å; E479-L483 WeakPolarHBondContact O-CG 3.41Å; E479-L483 PolarHBondContact O-N 3.49Å
480Q84.1Confident74.1Confident22 Ų2262 Ų6210%0.10335%0.345CS..Hα-helixtrans-61.7-49.7172.5177.9175.2-16.500111.9H171 K173 P476 L477 R482 L483 E484H171-Q480 PolarHBondContact O-NE2 2.99Å; K173-Q480 VanDerWaalsContact CE-CD 3.46Å; K173-Q480 VanDerWaalsContact CE-OE1 3.24Å; P476-Q480 PolarHBondContact O-N 3.45Å; L477-Q480 WeakPolarHBondContact O-CB 3.35Å; L477-Q480 PolarHBondContact O-N 3.35Å; L477-Q480 VanDerWaalsContact O-N 3.15Å; Q480-R482 VanDerWaalsContact C-N 3.32Å; Q480-R482 PolarHBondContact O-N 2.91Å; Q480-L483 WeakPolarHBondContact O-CB 3.48Å; Q480-L483 PolarHBondContact O-N 3.44Å; Q480-E484 HydrophobicContact CG-CG 4.49Å; Q480-E484 WeakPolarHBondContact CG-OE1 3.35Å; Q480-E484 PolarHBondContact NE2-OE1 2.94Å; Q480-E484 PolarHBondContact O-N 2.9Å
481V86.4Confident76Confident0 Ų062.1 Ų62.10%034%0.337CS..Hα-helixtrans-58.6-45.6-179.2172.50000110.5V17 L52 L66 L68 L170 L477 E484 A485V17-V481 HydrophobicContact CG1-CG1 3.89Å; V17-V481 HydrophobicContact CG2-CG1 3.98Å; V17-V481 HydrophobicContact CG2-CG2 4.47Å; L52-V481 HydrophobicContact CD1-CG2 4.38Å; L52-V481 HydrophobicContact CD2-CB 4.05Å; L52-V481 HydrophobicContact CD2-CG1 3.91Å; L66-V481 HydrophobicContact CD2-CG1 4.48Å; L68-V481 HydrophobicContact CD2-CG1 4.45Å; L68-V481 HydrophobicContact CD2-CG2 3.86Å; L170-V481 HydrophobicContact CD1-CG2 4.24Å; L170-V481 HydrophobicContact CD2-CG2 3.94Å; L477-V481 HydrophobicContact CD1-CG2 4.27Å; L477-V481 HydrophobicContact CG-CG2 4.32Å; L477-V481 VanDerWaalsContact O-CG2 3.3Å; L477-V481 WeakPolarHBondContact O-CG2 3.27Å; L477-V481 PolarHBondContact O-N 3.4Å; V481-E484 PolarHBondContact O-N 2.91Å; V481-A485 WeakPolarHBondContact O-CB 3.32Å; V481-A485 PolarHBondContact O-N 3.41Å
482R84.1Confident77.6Confident49 Ų4960.2 Ų60.219%0.18532%0.318CS..Hα-helixtrans-64.9-40.5177.4-71-175.8-176.6169.913.3112.5P54 D62 L66 A478 Q480 A485 D486P54-R482 PolarHBondContact O-NH2 2.84Å; D62-R482 IonicContact OD2-CZ 3.72Å; D62-R482 IonicContact OD2-NH1 3.84Å; D62-R482 PolarHBondContact OD2-NH1 3.41Å; L66-R482 HydrophobicContact CD1-CG 4.08Å; A478-R482 WeakPolarHBondContact O-CG 3.31Å; A478-R482 PolarHBondContact O-N 3.25Å; Q480-R482 VanDerWaalsContact C-N 3.32Å; Q480-R482 PolarHBondContact O-N 2.91Å; R482-A485 PolarHBondContact O-N 2.98Å; R482-D486 PolarHBondContact O-N 3.03Å
483L81.1Confident79.4Confident38 Ų3856.8 Ų56.820%0.19930%0.301CS..Hα-helixtrans-60-47.6175.5-86170.5000112.2R456 M460 L475 E479 Q480 D486 M487R456-L483 PolarHBondContact NH2-O 3.33Å; M460-L483 HydrophobicContact CB-CD2 4.5Å; M460-L483 HydrophobicContact CE-CD1 4.28Å; M460-L483 HydrophobicContact CE-CD2 3.45Å; M460-L483 VanDerWaalsContact CE-CD2 3.45Å; M460-L483 HydrophobicContact CE-CG 3.97Å; M460-L483 HydrophobicContact CG-CD2 3.7Å; M460-L483 HydrophobicContact SD-CD2 3.86Å; L475-L483 HydrophobicContact CD1-CD1 4.37Å; E479-L483 HydrophobicContact CG-CD1 4.27Å; E479-L483 VanDerWaalsContact O-CB 3.31Å; E479-L483 WeakPolarHBondContact O-CB 3.46Å; E479-L483 VanDerWaalsContact O-CG 3.27Å; E479-L483 WeakPolarHBondContact O-CG 3.41Å; E479-L483 PolarHBondContact O-N 3.49Å; Q480-L483 WeakPolarHBondContact O-CB 3.48Å; Q480-L483 PolarHBondContact O-N 3.44Å; L483-D486 PolarHBondContact O-N 2.92Å; L483-M487 WeakPolarHBondContact O-CG 3.5Å
484E87.1Confident81.1Confident11 Ų1148.2 Ų48.25%0.05126%0.264CS..Hα-helixtrans-68.8-37.4179.3-71.8179.8-141.900111.4F168 H171 Q480 V481 D486 M487 K541F168-E484 HydrophobicContact CE2-CB 3.89Å; H171-E484 IonicContact CD2-OE2 3.6Å; H171-E484 PolarHBondContact N-OE2 2.78Å; Q480-E484 HydrophobicContact CG-CG 4.49Å; Q480-E484 WeakPolarHBondContact CG-OE1 3.35Å; Q480-E484 PolarHBondContact NE2-OE1 2.94Å; Q480-E484 PolarHBondContact O-N 2.9Å; V481-E484 PolarHBondContact O-N 2.91Å; E484-D486 PolarHBondContact O-N 3.24Å; E484-M487 HydrophobicContact CG-SD 4.25Å; E484-M487 WeakPolarHBondContact O-CB 3.1Å; E484-M487 PolarHBondContact O-N 2.77Å; E484-K541 WeakPolarHBondContact O-CE 3.24Å; E484-K541 WeakPolarHBondContact O-CG 3.47Å
485A86.9Confident82.6Confident8 Ų844.8 Ų44.87%0.06625%0.249CC..Hα-helixtrans-56.7-36.8175.700000112.8Q166 F168 V481 R482 M487 K541Q166-A485 PolarHBondContact NE2-O 2.83Å; F168-A485 HydrophobicContact CE1-CB 4.04Å; F168-A485 HydrophobicContact CZ-CB 3.83Å; V481-A485 WeakPolarHBondContact O-CB 3.32Å; V481-A485 PolarHBondContact O-N 3.41Å; R482-A485 PolarHBondContact O-N 2.98Å; A485-M487 VanDerWaalsContact C-N 3.35Å; A485-K541 WeakPolarHBondContact O-CE 3.33Å; A485-K541 PolarHBondContact O-NZ 3.15Å
486D84.1Confident83.9Confident119 Ų11943 Ų4364%0.63624%0.24SC*.THydrogen-bonded Turntrans-84.6-0.5178.2-73.3-18.2000113.6R456 R482 L483 E484R456-D486 PolarHBondContact NH1-O 2.52Å; R456-D486 PolarHBondContact NH2-O 2.68Å; R482-D486 PolarHBondContact O-N 3.03Å; L483-D486 PolarHBondContact O-N 2.92Å; E484-D486 PolarHBondContact O-N 3.24Å
487M84.1Confident84.7Confident27 Ų2740.7 Ų40.713%0.13322%0.224CC..SBendtrans-77.5158.2176-72.71766900111.4L483 E484 A485 V539 F540 K541L483-M487 WeakPolarHBondContact O-CG 3.5Å; E484-M487 HydrophobicContact CG-SD 4.25Å; E484-M487 WeakPolarHBondContact O-CB 3.1Å; E484-M487 PolarHBondContact O-N 2.77Å; A485-M487 VanDerWaalsContact C-N 3.35Å; M487-V539 VanDerWaalsContact CE-C 3.48Å; M487-V539 VanDerWaalsContact CE-O 3.23Å; M487-V539 WeakPolarHBondContact CE-O 3.44Å; M487-F540 WeakPolarHBondContact CE-O 3.44Å; M487-K541 HydrophobicContact CB-CG 3.7Å; M487-K541 WeakPolarHBondContact O-CE 3.39Å; M487-K541 PolarHBondContact O-NZ 3.31Å
488S84.9Confident85.3Confident57 Ų5739.1 Ų39.140%0.39922%0.216SC..BIsolated β-bridgetrans-69.2143.2174.543.30000110.5V539 F540 K541S488-V539 PolarHBondContact OG-O 3.16Å; S488-F540 CarbonylContact O-C 3.2Å; S488-F540 VanDerWaalsContact O-CA 3.32Å; S488-F540 WeakPolarHBondContact O-CA 3.48Å; S488-F540 VanDerWaalsContact OG-CD1 3.23Å; S488-F540 WeakPolarHBondContact OG-CD1 3.34Å; S488-K541 PolarHBondContact O-N 2.95Å
489T87.3Confident85.8Confident77 Ų7739.3 Ų39.347%0.47222%0.215SC..PPolyproline II helixtrans-82.3134.1173.4-56.30000109.2L491T489-L491 PolarHBondContact O-N 2.92Å
490Y85.4Confident86.5Confident27 Ų2736.8 Ų36.811%0.10620%0.203CC..PPolyproline II helixtrans-73.5121.3170.9-179.3-110.6000109.6G492 T493 D496 M536 F540 P543Y490-G492 VanDerWaalsContact CE1-C 3.48Å; Y490-G492 PolarHBondContact O-N 3.39Å; Y490-T493 HydrophobicContact CE1-CG2 4.31Å; Y490-T493 VanDerWaalsContact OH-CA 3.31Å; Y490-T493 WeakPolarHBondContact OH-CA 3.22Å; Y490-T493 WeakPolarHBondContact OH-CG2 3.02Å; Y490-T493 PolarHBondContact OH-N 3.46Å; Y490-D496 PolarHBondContact OH-OD2 3.26Å; Y490-M536 HydrophobicContact CD1-SD 4.45Å; Y490-M536 HydrophobicContact CD2-SD 3.94Å; Y490-M536 HydrophobicContact CE1-CE 4.44Å; Y490-M536 HydrophobicContact CE1-SD 4.4Å; Y490-M536 HydrophobicContact CE2-SD 3.93Å; Y490-M536 HydrophobicContact CG-SD 4.2Å; Y490-F540 AromaticContact CD2-CD2 3.78Å; Y490-F540 HydrophobicContact CD2-CD2 3.78Å; Y490-F540 AromaticContact CD2-CE2 3.85Å; Y490-F540 HydrophobicContact CD2-CE2 3.85Å; Y490-F540 HydrophobicContact CD2-CG 4.26Å; Y490-F540 HydrophobicContact CD2-CZ 4.41Å; Y490-F540 HydrophobicContact CE2-CE2 4.5Å; Y490-F540 HydrophobicContact CG-CD2 4.48Å; Y490-P543 HydrophobicContact CD1-CB 3.97Å; Y490-P543 HydrophobicContact CD1-CG 4.18Å
491L77.7Confident87.1Confident139 Ų13936 Ų3673%0.72820%0.199SC*.  trans-83.88.3-173-67.2173.1000113.8T489T489-L491 PolarHBondContact O-N 2.92Å
492G82.3Confident87.3Confident28 Ų2837.3 Ų37.329%0.28921%0.206SC..  trans101.9172.8-178.300000112.7Y490 F494Y490-G492 VanDerWaalsContact CE1-C 3.48Å; Y490-G492 PolarHBondContact O-N 3.39Å; G492-F494 PolarHBondContact O-N 3.12Å
493T86.8Confident87.7Confident33 Ų3335.1 Ų35.120%0.20220%0.198CC..THydrogen-bonded Turntrans-799-174.851.80000113.9Y208 Y490 Y497Y208-T493 HydrophobicContact CG-CG2 4.19Å; Y490-T493 HydrophobicContact CE1-CG2 4.31Å; Y490-T493 VanDerWaalsContact OH-CA 3.31Å; Y490-T493 WeakPolarHBondContact OH-CA 3.22Å; Y490-T493 WeakPolarHBondContact OH-CG2 3.02Å; Y490-T493 PolarHBondContact OH-N 3.46Å; T493-Y497 WeakPolarHBondContact O-CD2 3.29Å; T493-Y497 PolarHBondContact O-N 2.92Å
494F87.6Confident88.4Confident20 Ų2033.3 Ų33.39%0.08819%0.188CC..Hα-helixtrans-62.2-52.6-174173.1-96.5000112V398 V401 G492 D496 Y497 L498 W554V398-F494 HydrophobicContact CB-CD2 4.21Å; V398-F494 HydrophobicContact CB-CE2 4.03Å; V398-F494 HydrophobicContact CG1-CD2 4.36Å; V398-F494 HydrophobicContact CG1-CE2 4.02Å; V398-F494 HydrophobicContact CG2-CD2 3.58Å; V398-F494 HydrophobicContact CG2-CE2 3.92Å; V401-F494 HydrophobicContact CB-CE1 4.25Å; V401-F494 HydrophobicContact CB-CE2 4.32Å; V401-F494 HydrophobicContact CB-CZ 3.59Å; V401-F494 HydrophobicContact CG1-CE1 3.64Å; V401-F494 HydrophobicContact CG1-CE2 4.49Å; V401-F494 HydrophobicContact CG1-CZ 3.35Å; V401-F494 HydrophobicContact CG2-CZ 4.5Å; G492-F494 PolarHBondContact O-N 3.12Å; F494-D496 VanDerWaalsContact C-N 3.31Å; F494-Y497 PolarHBondContact O-N 3.47Å; F494-L498 HydrophobicContact CE1-CD2 4.05Å; F494-L498 HydrophobicContact CZ-CD2 4.26Å; F494-L498 WeakPolarHBondContact O-CB 3.27Å; F494-L498 PolarHBondContact O-N 3.08Å; F494-W554 HydrophobicContact CD2-CH2 4.25Å; F494-W554 AromaticContact CD2-CZ2 3.55Å; F494-W554 HydrophobicContact CD2-CZ2 3.55Å; F494-W554 AromaticContact CE2-CH2 3.85Å; F494-W554 HydrophobicContact CE2-CH2 3.85Å; F494-W554 AromaticContact CE2-CZ2 3.59Å; F494-W554 HydrophobicContact CE2-CZ2 3.59Å; F494-W554 HydrophobicContact CG-CZ2 4.4Å; F494-W554 HydrophobicContact CZ-CH2 4.42Å; F494-W554 HydrophobicContact CZ-CZ2 4.49Å; F494-W554 WeakPolarHBondContact O-CZ2 3.49Å
495D86.9Confident88.7Confident62 Ų6232.8 Ų32.833%0.33219%0.186SC..Hα-helixtrans-66.3-39-177.5-64.6-52.3000110.4R375 L498 E499R375-D495 IonicContact CZ-OD1 2.96Å; R375-D495 IonicContact CZ-OD2 3.88Å; R375-D495 IonicContact NH1-OD1 2.74Å; R375-D495 PolarHBondContact NH1-OD1 3.13Å; R375-D495 IonicContact NH1-OD2 2.96Å; R375-D495 PolarHBondContact NH1-OD2 3.31Å; R375-D495 IonicContact NH2-OD1 3.98Å; R375-D495 IonicContact NH2-OD2 2.93Å; R375-D495 PolarHBondContact NH2-OD2 3.03Å; D495-L498 WeakPolarHBondContact O-CB 3.44Å; D495-L498 PolarHBondContact O-N 2.89Å; D495-E499 PolarHBondContact O-N 3.17Å
496D90.6Very high88.9Confident14 Ų1433 Ų338%0.07519%0.185CC..Hα-helixtrans-64.6-43.4178.7-45-37.9000112.3Y208 Y490 F494 L500Y208-D496 HydrophobicContact CD2-CB 4.11Å; Y208-D496 HydrophobicContact CE1-CB 4.12Å; Y208-D496 HydrophobicContact CE2-CB 3.41Å; Y208-D496 VanDerWaalsContact CE2-CB 3.41Å; Y208-D496 VanDerWaalsContact CZ-CB 3.43Å; Y490-D496 PolarHBondContact OH-OD2 3.26Å; F494-D496 VanDerWaalsContact C-N 3.31Å; D496-L500 PolarHBondContact O-N 3.23Å
497Y93.7Very high89.2Confident8 Ų827.6 Ų27.63%0.03116%0.157CC..Hα-helixtrans-69.9-33.9173.1-81.4-64.7000112.9Y208 F211 T493 F494 E499 L500 F501 I551 W554Y208-Y497 WeakPolarHBondContact CA-OH 3.23Å; Y208-Y497 HydrophobicContact CD2-CD1 4.12Å; Y208-Y497 HydrophobicContact CD2-CD2 4.24Å; Y208-Y497 AromaticContact CD2-CE1 3.96Å; Y208-Y497 HydrophobicContact CD2-CE1 3.96Å; Y208-Y497 HydrophobicContact CD2-CE2 4.07Å; Y208-Y497 HydrophobicContact CD2-CG 4.24Å; Y208-Y497 AromaticContact CD2-CZ 3.93Å; Y208-Y497 PolarHBondContact N-OH 3.28Å; F211-Y497 HydrophobicContact CB-CE1 4.11Å; F211-Y497 AromaticContact CD1-CD1 3.9Å; F211-Y497 HydrophobicContact CD1-CD1 3.9Å; F211-Y497 AromaticContact CD1-CE1 3.61Å; F211-Y497 HydrophobicContact CD1-CE1 3.61Å; F211-Y497 HydrophobicContact CE1-CD1 4.29Å; F211-Y497 HydrophobicContact CE1-CE1 4.36Å; F211-Y497 HydrophobicContact CG-CE1 4.07Å; T493-Y497 WeakPolarHBondContact O-CD2 3.29Å; T493-Y497 PolarHBondContact O-N 2.92Å; F494-Y497 PolarHBondContact O-N 3.47Å; Y497-E499 VanDerWaalsContact C-N 3.3Å; Y497-E499 PolarHBondContact O-N 3.47Å; Y497-L500 PolarHBondContact O-N 2.83Å; Y497-F501 WeakPolarHBondContact O-CB 3.39Å; Y497-F501 PolarHBondContact O-N 3.35Å; Y497-I551 HydrophobicContact CE1-CB 4.16Å; Y497-I551 HydrophobicContact CE1-CG2 3.97Å; Y497-I551 VanDerWaalsContact OH-CG2 3.3Å; Y497-I551 WeakPolarHBondContact OH-CG2 3.3Å; Y497-W554 HydrophobicContact CD1-CG 4.35Å; Y497-W554 AromaticContact CD2-CD1 3.61Å; Y497-W554 HydrophobicContact CD2-CG 4.36Å; Y497-W554 AromaticContact CD2-NE1 3.57Å; Y497-W554 AromaticContact CG-CD1 3.68Å; Y497-W554 HydrophobicContact CG-CD2 4.18Å; Y497-W554 AromaticContact CG-CG 4Å; Y497-W554 HydrophobicContact CG-CG 4Å; Y497-W554 AromaticContact CG-NE1 3.72Å
498L91.5Very high89.7Confident16 Ų1626.5 Ų26.58%0.08415%0.151CC..Hα-helixtrans-61.4-42177.3179.165.9000110.7N405 F494 D495 F501 L502 W554N405-L498 HydrophobicContact CB-CD1 4.21Å; N405-L498 WeakPolarHBondContact ND2-CD2 3.33Å; F494-L498 HydrophobicContact CE1-CD2 4.05Å; F494-L498 HydrophobicContact CZ-CD2 4.26Å; F494-L498 WeakPolarHBondContact O-CB 3.27Å; F494-L498 PolarHBondContact O-N 3.08Å; D495-L498 WeakPolarHBondContact O-CB 3.44Å; D495-L498 PolarHBondContact O-N 2.89Å; L498-F501 HydrophobicContact CD1-CD1 4.44Å; L498-F501 WeakPolarHBondContact O-CB 3.26Å; L498-F501 PolarHBondContact O-N 2.76Å; L498-L502 HydrophobicContact CD1-CG 4.38Å; L498-L502 HydrophobicContact CG-CD1 4.32Å; L498-L502 WeakPolarHBondContact O-CG 3.48Å; L498-L502 PolarHBondContact O-N 3.07Å; L498-W554 VanDerWaalsContact CA-CH2 3.44Å; L498-W554 HydrophobicContact CB-CH2 3.69Å; L498-W554 HydrophobicContact CB-CZ2 4.44Å; L498-W554 HydrophobicContact CB-CZ3 4.42Å; L498-W554 HydrophobicContact CD1-CH2 4.08Å; L498-W554 HydrophobicContact CD1-CZ3 4.41Å
499E90.1Very high90Very high17 Ų1723.8 Ų23.88%0.07913%0.132CC..Hα-helixtrans-57.9-52.9175.2-176.3-179.2162.900111.1D495 Y497 F501 L502 L503 N524D495-E499 PolarHBondContact O-N 3.17Å; Y497-E499 VanDerWaalsContact C-N 3.3Å; Y497-E499 PolarHBondContact O-N 3.47Å; E499-F501 PolarHBondContact O-N 3.17Å; E499-L502 PolarHBondContact O-N 3.06Å; E499-L502 VanDerWaalsContact O-N 3.15Å; E499-L503 HydrophobicContact CG-CD1 3.96Å; E499-L503 HydrophobicContact CG-CG 4.4Å; E499-L503 WeakPolarHBondContact O-CB 3.45Å; E499-L503 VanDerWaalsContact O-CG 3.31Å; E499-L503 WeakPolarHBondContact O-CG 3.27Å; E499-L503 PolarHBondContact O-N 3.36Å; E499-N524 PolarHBondContact OE1-ND2 3.21Å; E499-N524 VanDerWaalsContact OE1-ND2 3.12Å
500L94Very high90.1Very high1 Ų120.1 Ų20.11%0.00511%0.11CC..Hα-helixtrans-59.3-36178.1-61.1-178.8000112.4Y208 F211 L212 F215 D496 Y497 L503 F504 F558Y208-L500 HydrophobicContact CE2-CD1 3.94Å; F211-L500 HydrophobicContact CD1-CD1 3.79Å; F211-L500 HydrophobicContact CE1-CB 4.42Å; F211-L500 HydrophobicContact CE1-CD1 4.02Å; L212-L500 HydrophobicContact CB-CD1 4.26Å; L212-L500 HydrophobicContact CD1-CD1 3.98Å; L212-L500 HydrophobicContact CD1-CD2 3.59Å; L212-L500 HydrophobicContact CD1-CG 4.37Å; F215-L500 HydrophobicContact CD1-CD2 4.3Å; D496-L500 PolarHBondContact O-N 3.23Å; Y497-L500 PolarHBondContact O-N 2.83Å; L500-L503 HydrophobicContact CD2-CD1 4.46Å; L500-F504 WeakPolarHBondContact O-CB 3.4Å; L500-F504 PolarHBondContact O-N 2.86Å; L500-F558 HydrophobicContact CB-CZ 4.22Å
501F95.4Very high90Very high5 Ų519 Ų192%0.02211%0.106CC..Hα-helixtrans-66-44.8176.3173.9-100.2000112.5L402 F406 Y497 L498 E499 F504 G505 W554 A557 F558 M561L402-F501 HydrophobicContact CD1-CD1 4.3Å; L402-F501 HydrophobicContact CD1-CE1 4.17Å; L402-F501 HydrophobicContact CD1-CE2 4.44Å; L402-F501 HydrophobicContact CD1-CG 4.47Å; L402-F501 HydrophobicContact CD1-CZ 4.22Å; L402-F501 HydrophobicContact CD2-CE1 3.84Å; L402-F501 HydrophobicContact CD2-CZ 3.76Å; L402-F501 HydrophobicContact CG-CD1 4.22Å; L402-F501 HydrophobicContact CG-CE1 3.81Å; L402-F501 HydrophobicContact CG-CZ 4.12Å; F406-F501 HydrophobicContact CB-CE1 4.44Å; F406-F501 HydrophobicContact CD2-CE1 4.21Å; F406-F501 HydrophobicContact CD2-CZ 4.28Å; Y497-F501 WeakPolarHBondContact O-CB 3.39Å; Y497-F501 PolarHBondContact O-N 3.35Å; L498-F501 HydrophobicContact CD1-CD1 4.44Å; L498-F501 WeakPolarHBondContact O-CB 3.26Å; L498-F501 PolarHBondContact O-N 2.76Å; E499-F501 PolarHBondContact O-N 3.17Å; F501-F504 PolarHBondContact O-N 2.98Å; F501-G505 PolarHBondContact O-N 3.43Å; F501-W554 HydrophobicContact CB-CE3 4.2Å; F501-W554 HydrophobicContact CB-CZ3 3.82Å; F501-W554 HydrophobicContact CG-CZ3 4.12Å; F501-A557 HydrophobicContact CD2-CB 4.08Å; F501-A557 HydrophobicContact CE2-CB 3.75Å; F501-A557 WeakPolarHBondContact CE2-O 3.46Å; F501-A557 HydrophobicContact CZ-CB 4.39Å; F501-F558 HydrophobicContact CB-CE1 4.23Å; F501-F558 HydrophobicContact CB-CE2 4.45Å; F501-F558 HydrophobicContact CB-CZ 3.91Å; F501-F558 HydrophobicContact CD2-CD1 4.29Å; F501-F558 HydrophobicContact CD2-CE1 4.33Å; F501-F558 HydrophobicContact CD2-CG 4.43Å; F501-F558 HydrophobicContact CD2-CZ 4.49Å; F501-M561 HydrophobicContact CD1-CE 4.43Å; F501-M561 HydrophobicContact CD2-CE 4.5Å; F501-M561 HydrophobicContact CE1-CE 3.72Å; F501-M561 HydrophobicContact CE2-CB 3.87Å; F501-M561 HydrophobicContact CE2-CE 3.79Å; F501-M561 HydrophobicContact CZ-CB 4.37Å; F501-M561 HydrophobicContact CZ-CE 3.37Å
502L91.9Very high90.1Very high28 Ų2812.7 Ų12.715%0.1477%0.074CC..Hα-helixtrans-66.2-43.1176.7-67.2177.8000111.1C409 F410 L498 E499 F504 G505 Y506C409-L502 HydrophobicContact CB-CD2 4.16Å; F410-L502 HydrophobicContact CE2-CD2 3.75Å; F410-L502 HydrophobicContact CZ-CD2 4.27Å; L498-L502 HydrophobicContact CD1-CG 4.38Å; L498-L502 HydrophobicContact CG-CD1 4.32Å; L498-L502 WeakPolarHBondContact O-CG 3.48Å; L498-L502 PolarHBondContact O-N 3.07Å; E499-L502 PolarHBondContact O-N 3.06Å; E499-L502 VanDerWaalsContact O-N 3.15Å; L502-F504 VanDerWaalsContact C-N 3.33Å; L502-F504 PolarHBondContact O-N 2.77Å; L502-G505 WeakPolarHBondContact O-CA 3.41Å; L502-G505 PolarHBondContact O-N 2.81Å; L502-Y506 HydrophobicContact CB-CE2 4.41Å; L502-Y506 WeakPolarHBondContact O-CD2 3.43Å; L502-Y506 PolarHBondContact O-N 3.16Å
503L92.4Very high90.2Very high2 Ų212.8 Ų12.81%0.017%0.068CC..Hα-helixtrans-58-44.5173.9-71.6175.2000112L434 Q438 E499 L500 G505 Y506 V507 V521L434-L503 HydrophobicContact CD1-CD2 4.05Å; Q438-L503 VanDerWaalsContact NE2-CD2 3.29Å; E499-L503 HydrophobicContact CG-CD1 3.96Å; E499-L503 HydrophobicContact CG-CG 4.4Å; E499-L503 WeakPolarHBondContact O-CB 3.45Å; E499-L503 VanDerWaalsContact O-CG 3.31Å; E499-L503 WeakPolarHBondContact O-CG 3.27Å; E499-L503 PolarHBondContact O-N 3.36Å; L500-L503 HydrophobicContact CD2-CD1 4.46Å; L503-G505 VanDerWaalsContact C-N 3.31Å; L503-G505 PolarHBondContact O-N 3.21Å; L503-Y506 PolarHBondContact O-N 3.04Å; L503-V507 WeakPolarHBondContact O-CG2 3.33Å; L503-V507 PolarHBondContact O-N 3.29Å; L503-V507 VanDerWaalsContact O-N 3.13Å; L503-V521 HydrophobicContact CB-CG1 3.84Å; L503-V521 HydrophobicContact CB-CG2 4.23Å; L503-V521 HydrophobicContact CD1-CG1 4.23Å; L503-V521 HydrophobicContact CD2-CG1 4.37Å; L503-V521 HydrophobicContact CD2-CG2 3.86Å; L503-V521 HydrophobicContact CG-CG1 4.39Å
504F95.1Very high90.2Very high0 Ų012.3 Ų12.30%06%0.063CC..Hα-helixtrans-61.2-40173.1-177.6-116.4000112.4F215 C251 I254 L255 L500 F501 L502 V507 S508 F558 M561F215-F504 HydrophobicContact CE1-CB 4.47Å; F215-F504 HydrophobicContact CE2-CB 4.23Å; F215-F504 AromaticContact CE2-CD2 3.65Å; F215-F504 HydrophobicContact CE2-CD2 3.65Å; F215-F504 HydrophobicContact CE2-CE2 4.38Å; F215-F504 HydrophobicContact CE2-CG 4.19Å; F215-F504 HydrophobicContact CZ-CB 3.6Å; F215-F504 AromaticContact CZ-CD2 3.68Å; F215-F504 HydrophobicContact CZ-CD2 3.68Å; F215-F504 HydrophobicContact CZ-CG 4.01Å; C251-F504 HydrophobicContact CB-CE2 4.44Å; C251-F504 HydrophobicContact CB-CZ 4.12Å; I254-F504 HydrophobicContact CD1-CE2 4.25Å; L255-F504 HydrophobicContact CD1-CZ 4.47Å; L500-F504 WeakPolarHBondContact O-CB 3.4Å; L500-F504 PolarHBondContact O-N 2.86Å; F501-F504 PolarHBondContact O-N 2.98Å; L502-F504 VanDerWaalsContact C-N 3.33Å; L502-F504 PolarHBondContact O-N 2.77Å; F504-V507 PolarHBondContact O-N 3.03Å; F504-S508 VanDerWaalsContact O-CB 3.26Å; F504-S508 WeakPolarHBondContact O-CB 3.26Å; F504-S508 PolarHBondContact O-N 2.95Å; F504-S508 PolarHBondContact O-OG 3.45Å; F504-F558 HydrophobicContact CB-CD1 3.98Å; F504-F558 HydrophobicContact CB-CE1 3.65Å; F504-F558 AromaticContact CD1-CD1 3.48Å; F504-F558 HydrophobicContact CD1-CD1 3.48Å; F504-F558 VanDerWaalsContact CD1-CD1 3.48Å; F504-F558 HydrophobicContact CD1-CE1 4.08Å; F504-F558 HydrophobicContact CE1-CD1 4.1Å; F504-F558 AromaticContact CG-CD1 3.8Å; F504-F558 HydrophobicContact CG-CD1 3.8Å; F504-F558 AromaticContact CG-CE1 3.99Å; F504-F558 HydrophobicContact CG-CE1 3.99Å; F504-M561 HydrophobicContact CD1-CB 4.12Å; F504-M561 HydrophobicContact CD1-CG 3.67Å; F504-M561 HydrophobicContact CE1-CB 4.08Å; F504-M561 HydrophobicContact CE1-CG 3.85Å
505G94Very high90Very high0 Ų012 Ų120%06%0.063CC..Hα-helixtrans-59.9-47.1175.500000112.4F501 L502 L503 V507 S508 L509 M561F501-G505 PolarHBondContact O-N 3.43Å; L502-G505 WeakPolarHBondContact O-CA 3.41Å; L502-G505 PolarHBondContact O-N 2.81Å; L503-G505 VanDerWaalsContact C-N 3.31Å; L503-G505 PolarHBondContact O-N 3.21Å; G505-V507 VanDerWaalsContact C-N 3.31Å; G505-V507 PolarHBondContact O-N 3.1Å; G505-S508 PolarHBondContact O-N 3.19Å; G505-L509 WeakPolarHBondContact O-CB 3.32Å; G505-L509 VanDerWaalsContact O-CG 3.28Å; G505-L509 WeakPolarHBondContact O-CG 3.07Å; G505-L509 PolarHBondContact O-N 3Å; G505-M561 VanDerWaalsContact CA-SD 3.59Å
506Y90.4Very high90.1Very high14 Ų1410.6 Ų10.66%0.0556%0.056CC..Hα-helixtrans-60.6-39.4176.9-68.2-56.5000112.8F410 L413 L430 L434 L502 L503F410-Y506 HydrophobicContact CD1-CD1 4.34Å; F410-Y506 HydrophobicContact CD1-CE1 4.16Å; F410-Y506 AromaticContact CE1-CD1 3.51Å; F410-Y506 HydrophobicContact CE1-CD1 3.51Å; F410-Y506 AromaticContact CE1-CE1 3.57Å; F410-Y506 HydrophobicContact CE1-CE1 3.57Å; F410-Y506 HydrophobicContact CE1-CG 4.07Å; F410-Y506 HydrophobicContact CZ-CD1 4.29Å; F410-Y506 HydrophobicContact CZ-CE1 4.29Å; F410-Y506 HydrophobicContact CZ-CG 4.49Å; L413-Y506 HydrophobicContact CD1-CD1 4.14Å; L413-Y506 HydrophobicContact CD1-CE1 3.8Å; L430-Y506 HydrophobicContact CD1-CD1 3.34Å; L430-Y506 HydrophobicContact CD1-CE1 4.12Å; L430-Y506 HydrophobicContact CD1-CG 4.09Å; L434-Y506 HydrophobicContact CD1-CD2 3.54Å; L434-Y506 HydrophobicContact CD1-CE2 4.34Å; L434-Y506 HydrophobicContact CD1-CG 3.78Å; L502-Y506 HydrophobicContact CB-CE2 4.41Å; L502-Y506 WeakPolarHBondContact O-CD2 3.43Å; L502-Y506 PolarHBondContact O-N 3.16Å; L503-Y506 PolarHBondContact O-N 3.04Å
507V91.9Very high90.1Very high5 Ų510 Ų103%0.035%0.053CC..Hα-helixtrans-73.4-43.4178.4175.60000112L219 M222 L503 F504 G505 S511 A517 A518 V521L219-V507 HydrophobicContact CD2-CG1 4.29Å; M222-V507 HydrophobicContact SD-CG1 3.7Å; L503-V507 WeakPolarHBondContact O-CG2 3.33Å; L503-V507 PolarHBondContact O-N 3.29Å; L503-V507 VanDerWaalsContact O-N 3.13Å; F504-V507 PolarHBondContact O-N 3.03Å; G505-V507 VanDerWaalsContact C-N 3.31Å; G505-V507 PolarHBondContact O-N 3.1Å; V507-S511 WeakPolarHBondContact O-CA 3.23Å; V507-S511 WeakPolarHBondContact O-CB 3.33Å; V507-A517 HydrophobicContact CG2-CB 4.16Å; V507-A518 HydrophobicContact CG1-CB 3.96Å; V507-A518 HydrophobicContact CG2-CB 4.45Å; V507-V521 HydrophobicContact CG2-CB 3.99Å; V507-V521 HydrophobicContact CG2-CG1 4.49Å; V507-V521 HydrophobicContact CG2-CG2 3.44Å; V507-V521 VanDerWaalsContact CG2-CG2 3.44Å
508S93.2Very high90Very high3 Ų39.9 Ų9.92%0.0215%0.053CC..Hα-helixtrans-84.2-41.1-170.860.80000113.6F504 G505 A565 N569F504-S508 VanDerWaalsContact O-CB 3.26Å; F504-S508 WeakPolarHBondContact O-CB 3.26Å; F504-S508 PolarHBondContact O-N 2.95Å; F504-S508 PolarHBondContact O-OG 3.45Å; G505-S508 PolarHBondContact O-N 3.19Å; S508-A565 WeakPolarHBondContact O-CB 3.31Å; S508-N569 PolarHBondContact O-ND2 3.45Å
509L92.6Very high90.1Very high0 Ų011 Ų110%06%0.06CC..Hα-helixtrans-70.4-43.9-175.8-67173000112.4F406 F410 F414 G505 M561 I564 A565 T568F406-L509 HydrophobicContact CE2-CD1 4.2Å; F410-L509 HydrophobicContact CD1-CD1 3.75Å; F410-L509 HydrophobicContact CD2-CD1 4.36Å; F410-L509 HydrophobicContact CE1-CD1 3.9Å; F410-L509 HydrophobicContact CG-CD1 3.99Å; F410-L509 HydrophobicContact CZ-CD1 4.3Å; F414-L509 HydrophobicContact CZ-CD1 3.99Å; F414-L509 HydrophobicContact CZ-CD2 4.23Å; G505-L509 WeakPolarHBondContact O-CB 3.32Å; G505-L509 VanDerWaalsContact O-CG 3.28Å; G505-L509 WeakPolarHBondContact O-CG 3.07Å; G505-L509 PolarHBondContact O-N 3Å; L509-M561 HydrophobicContact CD1-SD 3.68Å; L509-M561 HydrophobicContact CD2-SD 3.9Å; L509-M561 HydrophobicContact CG-SD 3.72Å; L509-I564 HydrophobicContact CD2-CB 4.2Å; L509-I564 HydrophobicContact CD2-CG2 3.66Å; L509-A565 HydrophobicContact CD2-CB 4.16Å; L509-T568 HydrophobicContact CB-CG2 4.36Å; L509-T568 WeakPolarHBondContact O-CG2 3.45Å
510F88.5Confident90.1Very high0 Ų012.3 Ų12.30%07%0.068CC..SBendtrans-114.124.7-170.3-55.8-74.2000112.6F410 L413 F414 A417 L426 L430 C512 V513 Y514 T568 L572F410-F510 AromaticContact CD1-CE2 3.94Å; F410-F510 HydrophobicContact CD1-CE2 3.94Å; F410-F510 HydrophobicContact CE1-CE2 4.45Å; L413-F510 HydrophobicContact CB-CE1 4.22Å; L413-F510 HydrophobicContact CB-CE2 3.93Å; L413-F510 HydrophobicContact CB-CZ 3.56Å; L413-F510 HydrophobicContact CD1-CD2 4.28Å; L413-F510 HydrophobicContact CD1-CE2 3.78Å; L413-F510 HydrophobicContact CD1-CZ 4.3Å; F414-F510 HydrophobicContact CD1-CE1 4.33Å; F414-F510 HydrophobicContact CD1-CZ 4.01Å; F414-F510 HydrophobicContact CE1-CE1 4.43Å; F414-F510 AromaticContact CE1-CZ 3.97Å; F414-F510 HydrophobicContact CE1-CZ 3.97Å; A417-F510 HydrophobicContact CB-CE1 4.43Å; L426-F510 HydrophobicContact CD1-CD1 4.2Å; L426-F510 HydrophobicContact CD1-CE1 4.16Å; L426-F510 HydrophobicContact CD2-CD1 4.14Å; L430-F510 HydrophobicContact CD1-CD2 4.31Å; L430-F510 HydrophobicContact CD2-CB 3.61Å; L430-F510 HydrophobicContact CD2-CG 4.32Å; F510-C512 VanDerWaalsContact C-N 3.27Å; F510-C512 PolarHBondContact O-N 3.28Å; F510-V513 PolarHBondContact O-N 2.95Å; F510-Y514 PolarHBondContact O-N 3.35Å; F510-Y514 VanDerWaalsContact O-N 3.09Å; F510-T568 HydrophobicContact CE1-CG2 4.26Å; F510-L572 HydrophobicContact CD1-CD1 4.25Å
511S82.5Confident90Very high5 Ų512.3 Ų12.34%0.0357%0.068CC..THydrogen-bonded Turntrans-53.6-44.6-175.374.20000112.1F243 N247 V507 V513 Y514 N569F243-S511 VanDerWaalsContact CE1-O 3.32Å; F243-S511 WeakPolarHBondContact CE1-O 3.42Å; N247-S511 WeakPolarHBondContact ND2-CB 3.31Å; N247-S511 PolarHBondContact ND2-OG 2.88Å; V507-S511 WeakPolarHBondContact O-CA 3.23Å; V507-S511 WeakPolarHBondContact O-CB 3.33Å; S511-V513 PolarHBondContact O-N 3.14Å; S511-Y514 CarbonylContact O-C 3.51Å; S511-Y514 PolarHBondContact O-N 3.04Å; S511-N569 PolarHBondContact OG-OD1 3.27Å
512C81.3Confident89.9Confident6 Ų613.1 Ų13.14%0.0417%0.073CC..THydrogen-bonded Turntrans-64.1-28.8-179.3-59.60000113.1Y240 F510 N569Y240-C512 HydrophobicContact CD1-CB 4.26Å; Y240-C512 WeakPolarHBondContact CE1-O 3.39Å; F510-C512 VanDerWaalsContact C-N 3.27Å; F510-C512 PolarHBondContact O-N 3.28Å; C512-N569 PolarHBondContact SG-OD1 3.05Å
513V83.8Confident89.9Confident29 Ų2917 Ų1718%0.1769%0.093CC..THydrogen-bonded Turntrans-88.8-35.2-175178.20000111M423 L426 F510 S511 L572M423-V513 HydrophobicContact SD-CG2 4.23Å; L426-V513 HydrophobicContact CB-CG1 4.34Å; L426-V513 HydrophobicContact CD2-CB 4.31Å; L426-V513 HydrophobicContact CD2-CG1 3.96Å; L426-V513 HydrophobicContact CD2-CG2 3.88Å; L426-V513 HydrophobicContact CG-CG1 4.05Å; F510-V513 PolarHBondContact O-N 2.95Å; S511-V513 PolarHBondContact O-N 3.14Å; V513-L572 HydrophobicContact CG2-CD1 3.98Å; V513-L572 HydrophobicContact CG2-CD2 4.32Å
514Y86.2Confident89.8Confident23 Ų2317.3 Ų17.39%0.0910%0.095CC..  trans-137.979.5179.9-168.2-120.6000112.1L430 A431 F510 S511 L516 A517 L520L430-Y514 HydrophobicContact CD2-CD1 4.14Å; L430-Y514 HydrophobicContact CD2-CG 4.22Å; L430-Y514 HydrophobicContact CG-CD1 4.33Å; A431-Y514 HydrophobicContact CB-CE1 4.1Å; A431-Y514 HydrophobicContact CB-CE2 4.2Å; F510-Y514 PolarHBondContact O-N 3.35Å; F510-Y514 VanDerWaalsContact O-N 3.09Å; S511-Y514 CarbonylContact O-C 3.51Å; S511-Y514 PolarHBondContact O-N 3.04Å; Y514-L516 HydrophobicContact CE1-CB 4.19Å; Y514-L516 HydrophobicContact CE2-CB 4.06Å; Y514-L516 PolarHBondContact O-N 3.27Å; Y514-L516 VanDerWaalsContact O-N 3.12Å; Y514-A517 HydrophobicContact CD1-CB 3.83Å; Y514-A517 HydrophobicContact CE1-CB 4.4Å; Y514-A517 VanDerWaalsContact O-CB 3.3Å; Y514-A517 WeakPolarHBondContact O-CB 3.45Å; Y514-A517 PolarHBondContact O-N 3.07Å; Y514-L520 HydrophobicContact CE1-CD1 4.06Å
515P84.7Confident89.6Confident15 Ų1517.3 Ų17.310%0.09710%0.095CC..THydrogen-bonded Turntrans-60.7-23.8-178.2-2534.7000114.4F243 A517F243-P515 HydrophobicContact CE1-CB 4Å; F243-P515 HydrophobicContact CE1-CG 4.14Å; F243-P515 HydrophobicContact CZ-CB 4Å; P515-A517 PolarHBondContact O-N 3.09Å
516L88.3Confident89.4Confident32 Ų3219.5 Ų19.517%0.16811%0.108CC..THydrogen-bonded Turntrans-71.1-11.5176.4-72.5-173.6000114.2V227 Y230 Y514 A518 V519 L520V227-L516 HydrophobicContact CG2-CD2 4.26Å; Y230-L516 HydrophobicContact CD1-CD1 3.39Å; Y230-L516 HydrophobicContact CD1-CD2 4.23Å; Y230-L516 HydrophobicContact CD1-CG 3.88Å; Y230-L516 HydrophobicContact CD2-CD1 3.63Å; Y230-L516 HydrophobicContact CD2-CG 3.72Å; Y230-L516 HydrophobicContact CE1-CD1 3.47Å; Y230-L516 VanDerWaalsContact CE1-CD1 3.47Å; Y230-L516 HydrophobicContact CE1-CG 4.42Å; Y230-L516 HydrophobicContact CE2-CD1 3.7Å; Y230-L516 HydrophobicContact CE2-CG 4.27Å; Y230-L516 HydrophobicContact CG-CD1 3.45Å; Y230-L516 VanDerWaalsContact CG-CD1 3.45Å; Y230-L516 HydrophobicContact CG-CD2 4.04Å; Y230-L516 HydrophobicContact CG-CG 3.48Å; Y230-L516 VanDerWaalsContact CG-CG 3.48Å; Y514-L516 HydrophobicContact CE1-CB 4.19Å; Y514-L516 HydrophobicContact CE2-CB 4.06Å; Y514-L516 PolarHBondContact O-N 3.27Å; Y514-L516 VanDerWaalsContact O-N 3.12Å; L516-A518 PolarHBondContact O-N 3.23Å; L516-V519 HydrophobicContact CD2-CG2 4.14Å; L516-V519 WeakPolarHBondContact O-CB 3.39Å; L516-V519 PolarHBondContact O-N 3.22Å; L516-L520 PolarHBondContact O-N 3.36Å
517A90.3Very high89.2Confident2 Ų221.8 Ų21.82%0.01712%0.124CC..Hα-helixtrans-50.1-46.3176.900000111.4V507 Y514 P515 V519 L520 V521V507-A517 HydrophobicContact CG2-CB 4.16Å; Y514-A517 HydrophobicContact CD1-CB 3.83Å; Y514-A517 HydrophobicContact CE1-CB 4.4Å; Y514-A517 VanDerWaalsContact O-CB 3.3Å; Y514-A517 WeakPolarHBondContact O-CB 3.45Å; Y514-A517 PolarHBondContact O-N 3.07Å; P515-A517 PolarHBondContact O-N 3.09Å; A517-V519 VanDerWaalsContact C-N 3.28Å; A517-V519 PolarHBondContact O-N 3.31Å; A517-L520 PolarHBondContact O-N 2.92Å; A517-V521 WeakPolarHBondContact O-CG2 3.47Å; A517-V521 PolarHBondContact O-N 3.12Å
518A92.1Very high89.1Confident4 Ų421.6 Ų21.63%0.03312%0.122CC..Hα-helixtrans-60.9-34.8-178.400000112.9M222 A223 V507 L516 V522M222-A518 HydrophobicContact CB-CB 3.86Å; A223-A518 HydrophobicContact CB-CB 4.07Å; V507-A518 HydrophobicContact CG1-CB 3.96Å; V507-A518 HydrophobicContact CG2-CB 4.45Å; L516-A518 PolarHBondContact O-N 3.23Å; A518-V522 WeakPolarHBondContact O-CB 3.26Å; A518-V522 VanDerWaalsContact O-CG2 3.25Å; A518-V522 WeakPolarHBondContact O-CG2 3.46Å; A518-V522 PolarHBondContact O-N 3.21Å
519V92.5Very high88.9Confident39 Ų3922.3 Ų22.324%0.23613%0.127CC..Hα-helixtrans-65.2-47.6177.2-179.80000110.3A223 V227 L516 A517 V521 V522 L523A223-V519 HydrophobicContact CB-CG2 3.9Å; V227-V519 HydrophobicContact CG2-CG2 3.56Å; L516-V519 HydrophobicContact CD2-CG2 4.14Å; L516-V519 WeakPolarHBondContact O-CB 3.39Å; L516-V519 PolarHBondContact O-N 3.22Å; A517-V519 VanDerWaalsContact C-N 3.28Å; A517-V519 PolarHBondContact O-N 3.31Å; V519-V521 VanDerWaalsContact C-N 3.34Å; V519-V521 PolarHBondContact O-N 3.44Å; V519-V522 PolarHBondContact O-N 3.33Å; V519-L523 HydrophobicContact CG1-CD1 4.3Å; V519-L523 WeakPolarHBondContact O-CG 3.46Å; V519-L523 PolarHBondContact O-N 3.17Å
520L91.1Very high88.6Confident46 Ų4624.6 Ų24.624%0.24114%0.136CC..Hα-helixtrans-64.1-40.3179.9-64.6178000111.4L434 I435 Y514 L516 A517 L523 N524L434-L520 HydrophobicContact CD2-CB 3.47Å; L434-L520 VanDerWaalsContact CD2-CB 3.47Å; L434-L520 HydrophobicContact CD2-CD1 3.63Å; L434-L520 HydrophobicContact CD2-CG 4.18Å; I435-L520 HydrophobicContact CD1-CD1 4.25Å; I435-L520 HydrophobicContact CG1-CD1 3.88Å; Y514-L520 HydrophobicContact CE1-CD1 4.06Å; L516-L520 PolarHBondContact O-N 3.36Å; A517-L520 PolarHBondContact O-N 2.92Å; L520-L523 PolarHBondContact O-N 3.5Å; L520-N524 WeakPolarHBondContact O-CB 3.21Å; L520-N524 PolarHBondContact O-N 3.25Å
521V92.5Very high88.5Confident0 Ų025 Ų250%014%0.138CC..Hα-helixtrans-65.9-41.6175.5177.70000111.9L219 L434 L503 V507 A517 V519 L523 N524 N525L219-V521 HydrophobicContact CD1-CB 4.15Å; L219-V521 HydrophobicContact CD1-CG1 3.36Å; L434-V521 HydrophobicContact CD1-CG2 4.19Å; L434-V521 HydrophobicContact CD2-CG2 4.41Å; L503-V521 HydrophobicContact CB-CG1 3.84Å; L503-V521 HydrophobicContact CB-CG2 4.23Å; L503-V521 HydrophobicContact CD1-CG1 4.23Å; L503-V521 HydrophobicContact CD2-CG1 4.37Å; L503-V521 HydrophobicContact CD2-CG2 3.86Å; L503-V521 HydrophobicContact CG-CG1 4.39Å; V507-V521 HydrophobicContact CG2-CB 3.99Å; V507-V521 HydrophobicContact CG2-CG1 4.49Å; V507-V521 HydrophobicContact CG2-CG2 3.44Å; V507-V521 VanDerWaalsContact CG2-CG2 3.44Å; A517-V521 WeakPolarHBondContact O-CG2 3.47Å; A517-V521 PolarHBondContact O-N 3.12Å; V519-V521 VanDerWaalsContact C-N 3.34Å; V519-V521 PolarHBondContact O-N 3.44Å; V521-L523 VanDerWaalsContact C-N 3.33Å; V521-L523 PolarHBondContact O-N 3.31Å; V521-N524 PolarHBondContact O-N 3.21Å; V521-N525 VanDerWaalsContact O-CG 3.25Å; V521-N525 PolarHBondContact O-N 3.33Å; V521-N525 PolarHBondContact O-OD1 3.23Å
522V93.3Very high88.9Confident22 Ų2225 Ų2513%0.13314%0.138CC..Hα-helixtrans-61.9-42.7176168.20000111L219 V220 A223 A518 V519 N524 N525 V526L219-V522 HydrophobicContact CB-CG2 3.57Å; V220-V522 HydrophobicContact CG2-CG1 4.14Å; V220-V522 HydrophobicContact CG2-CG2 4.38Å; A223-V522 HydrophobicContact CB-CG2 4.26Å; A518-V522 WeakPolarHBondContact O-CB 3.26Å; A518-V522 VanDerWaalsContact O-CG2 3.25Å; A518-V522 WeakPolarHBondContact O-CG2 3.46Å; A518-V522 PolarHBondContact O-N 3.21Å; V519-V522 PolarHBondContact O-N 3.33Å; V522-N524 VanDerWaalsContact C-N 3.34Å; V522-N525 PolarHBondContact O-N 3.17Å; V522-V526 VanDerWaalsContact O-CG2 3.29Å; V522-V526 WeakPolarHBondContact O-CG2 3.25Å; V522-V526 PolarHBondContact O-N 3.15Å
523L90.8Very high89.3Confident109 Ų10924.7 Ų24.757%0.57114%0.136SC*.Hα-helixtrans-62.3-42.2176.3-69.7173.9000111.8V519 L520 V521 V526 T527V519-L523 HydrophobicContact CG1-CD1 4.3Å; V519-L523 WeakPolarHBondContact O-CG 3.46Å; V519-L523 PolarHBondContact O-N 3.17Å; L520-L523 PolarHBondContact O-N 3.5Å; V521-L523 VanDerWaalsContact C-N 3.33Å; V521-L523 PolarHBondContact O-N 3.31Å; L523-V526 PolarHBondContact O-N 3.16Å; L523-T527 PolarHBondContact O-N 3.03Å; L523-T527 PolarHBondContact O-OG1 3.28Å
524N90.2Very high89.4Confident9 Ų924.8 Ų24.85%0.04813%0.134CC..Hα-helixtrans-61.8-49.9175.2-169.274000111.6Q438 E499 L520 V521 V522 V526 T527 E528Q438-N524 HydrophobicContact CG-CB 4.16Å; Q438-N524 PolarHBondContact OE1-ND2 2.91Å; Q438-N524 VanDerWaalsContact OE1-ND2 3.13Å; Q438-N524 PolarHBondContact OE1-OD1 3.38Å; Q438-N524 VanDerWaalsContact OE1-OD1 3.08Å; E499-N524 PolarHBondContact OE1-ND2 3.21Å; E499-N524 VanDerWaalsContact OE1-ND2 3.12Å; L520-N524 WeakPolarHBondContact O-CB 3.21Å; L520-N524 PolarHBondContact O-N 3.25Å; V521-N524 PolarHBondContact O-N 3.21Å; V522-N524 VanDerWaalsContact C-N 3.34Å; N524-V526 VanDerWaalsContact C-N 3.25Å; N524-V526 PolarHBondContact O-N 2.86Å; N524-T527 PolarHBondContact O-N 3.01Å; N524-T527 VanDerWaalsContact O-N 3.07Å; N524-T527 PolarHBondContact O-OG1 3.31Å; N524-E528 WeakPolarHBondContact O-CB 3.47Å; N524-E528 PolarHBondContact O-N 2.88Å
525N91.7Very high89.5Confident0 Ų024.3 Ų24.30%013%0.133CC..Hα-helixtrans-65.1-32.2-177.7-64.2-1.6000112.1L212 T216 V521 V522 E528 V529L212-N525 HydrophobicContact CD1-CB 4.25Å; T216-N525 HydrophobicContact CG2-CB 4.01Å; T216-N525 WeakPolarHBondContact OG1-CB 3.49Å; V521-N525 VanDerWaalsContact O-CG 3.25Å; V521-N525 PolarHBondContact O-N 3.33Å; V521-N525 PolarHBondContact O-OD1 3.23Å; V522-N525 PolarHBondContact O-N 3.17Å; N525-E528 PolarHBondContact O-N 3.48Å; N525-V529 WeakPolarHBondContact O-CG2 3.43Å; N525-V529 PolarHBondContact O-N 2.98Å
526V89.6Confident89.6Confident47 Ų4724 Ų2429%0.28513%0.13SC..Hα-helixtrans-62.8-43.2173.7168.30000110.8T216 V522 L523 N524 E528 Y530T216-V526 HydrophobicContact CG2-CG2 3.95Å; V522-V526 VanDerWaalsContact O-CG2 3.29Å; V522-V526 WeakPolarHBondContact O-CG2 3.25Å; V522-V526 PolarHBondContact O-N 3.15Å; L523-V526 PolarHBondContact O-N 3.16Å; N524-V526 VanDerWaalsContact C-N 3.25Å; N524-V526 PolarHBondContact O-N 2.86Å; V526-E528 VanDerWaalsContact C-N 3.31Å; V526-Y530 HydrophobicContact CG1-CE2 4.47Å; V526-Y530 WeakPolarHBondContact O-CD2 3.29Å; V526-Y530 WeakPolarHBondContact O-CE2 3.25Å
527T86.8Confident89.6Confident62 Ų6222.6 Ų22.638%0.3812%0.123SC..Hα-helixtrans-69.1-34.7174.248.70000111.4Q442 L523 N524 V529 Y530 S531Q442-T527 PolarHBondContact OE1-OG1 2.9Å; L523-T527 PolarHBondContact O-N 3.03Å; L523-T527 PolarHBondContact O-OG1 3.28Å; N524-T527 PolarHBondContact O-N 3.01Å; N524-T527 VanDerWaalsContact O-N 3.07Å; N524-T527 PolarHBondContact O-OG1 3.31Å; T527-V529 PolarHBondContact O-N 3.37Å; T527-Y530 PolarHBondContact O-N 2.86Å; T527-Y530 VanDerWaalsContact O-N 3.1Å; T527-S531 PolarHBondContact O-N 3.5Å; T527-S531 PolarHBondContact O-OG 3.39Å
528E89.4Confident89.3Confident0 Ų025.3 Ų25.30%014%0.135CC..Hα-helixtrans-63.5-42.4-177.3-155.650.7-114.400113.1L212 N524 N525 V526 Y530 S531 D532 K535L212-E528 HydrophobicContact CD1-CB 4.5Å; N524-E528 WeakPolarHBondContact O-CB 3.47Å; N524-E528 PolarHBondContact O-N 2.88Å; N525-E528 PolarHBondContact O-N 3.48Å; V526-E528 VanDerWaalsContact C-N 3.31Å; E528-Y530 PolarHBondContact O-N 2.9Å; E528-Y530 VanDerWaalsContact O-N 3.07Å; E528-S531 VanDerWaalsContact CA-OG 3.23Å; E528-S531 WeakPolarHBondContact CA-OG 3.48Å; E528-S531 VanDerWaalsContact CD-OG 3.26Å; E528-S531 PolarHBondContact O-N 2.86Å; E528-S531 VanDerWaalsContact O-N 3.17Å; E528-S531 PolarHBondContact O-OG 2.93Å; E528-S531 PolarHBondContact OE1-OG 3.48Å; E528-S531 PolarHBondContact OE2-OG 3.18Å; E528-D532 WeakPolarHBondContact O-CB 3.49Å; E528-D532 PolarHBondContact O-N 3.22Å; E528-D532 VanDerWaalsContact OE1-CG 3.29Å; E528-D532 VanDerWaalsContact OE1-OD1 3.12Å; E528-K535 IonicContact OE1-NZ 3.71Å
529V88.6Confident88.9Confident18 Ų1826 Ų2611%0.10914%0.138CC..Hα-helixtrans-51.1-38.4174168.10000111.8Q192 L212 N525 T527 A533Q192-V529 HydrophobicContact CG-CG1 4.09Å; L212-V529 HydrophobicContact CD2-CB 4.32Å; L212-V529 HydrophobicContact CD2-CG2 3.63Å; L212-V529 HydrophobicContact CG-CG2 3.71Å; N525-V529 WeakPolarHBondContact O-CG2 3.43Å; N525-V529 PolarHBondContact O-N 2.98Å; T527-V529 PolarHBondContact O-N 3.37Å; V529-A533 VanDerWaalsContact O-CB 3.32Å; V529-A533 WeakPolarHBondContact O-CB 3.28Å
530Y86.9Confident88.7Confident49 Ų4926.2 Ų26.219%0.19214%0.136CC..Hα-helixtrans-86.6-36.4-179.6-62.3-80.7000113.2F187 K188 V526 T527 E528 F534F187-Y530 HydrophobicContact CD2-CE2 4.47Å; F187-Y530 HydrophobicContact CE2-CE2 4.23Å; K188-Y530 PolarHBondContact O-OH 3.34Å; V526-Y530 HydrophobicContact CG1-CE2 4.47Å; V526-Y530 WeakPolarHBondContact O-CD2 3.29Å; V526-Y530 WeakPolarHBondContact O-CE2 3.25Å; T527-Y530 PolarHBondContact O-N 2.86Å; T527-Y530 VanDerWaalsContact O-N 3.1Å; E528-Y530 PolarHBondContact O-N 2.9Å; E528-Y530 VanDerWaalsContact O-N 3.07Å; Y530-F534 WeakPolarHBondContact O-CB 3.42Å; Y530-F534 PolarHBondContact O-N 3.21Å
531S86.9Confident88.6Confident7 Ų724.4 Ų24.45%0.04913%0.127CC..Hα-helixtrans-67.3-44.3177.642.90000111.9T527 E528 F534 K535T527-S531 PolarHBondContact O-N 3.5Å; T527-S531 PolarHBondContact O-OG 3.39Å; E528-S531 VanDerWaalsContact CA-OG 3.23Å; E528-S531 WeakPolarHBondContact CA-OG 3.48Å; E528-S531 VanDerWaalsContact CD-OG 3.26Å; E528-S531 PolarHBondContact O-N 2.86Å; E528-S531 VanDerWaalsContact O-N 3.17Å; E528-S531 PolarHBondContact O-OG 2.93Å; E528-S531 PolarHBondContact OE1-OG 3.48Å; E528-S531 PolarHBondContact OE2-OG 3.18Å; S531-F534 WeakPolarHBondContact O-CB 3.32Å; S531-F534 PolarHBondContact O-N 3.44Å; S531-K535 WeakPolarHBondContact O-CG 3.4Å; S531-K535 PolarHBondContact O-N 3.31Å
532D89.3Confident88.7Confident6 Ų624.6 Ų24.63%0.03213%0.127CC..Hα-helixtrans-62.6-46.6176.3-82.3-23.4000112.4Y208 F209 E528 F534 K535 M536Y208-D532 VanDerWaalsContact CE1-OD2 3.3Å; Y208-D532 WeakPolarHBondContact CE1-OD2 3.4Å; Y208-D532 VanDerWaalsContact CZ-OD2 3.29Å; Y208-D532 PolarHBondContact OH-OD2 2.85Å; F209-D532 HydrophobicContact CE1-CB 3.52Å; F209-D532 HydrophobicContact CZ-CB 3.67Å; E528-D532 WeakPolarHBondContact O-CB 3.49Å; E528-D532 PolarHBondContact O-N 3.22Å; E528-D532 VanDerWaalsContact OE1-CG 3.29Å; E528-D532 VanDerWaalsContact OE1-OD1 3.12Å; D532-F534 PolarHBondContact O-N 2.88Å; D532-K535 PolarHBondContact O-N 2.92Å; D532-K535 WeakPolarHBondContact OD1-CE 3.33Å; D532-K535 IonicContact OD1-NZ 3.72Å; D532-K535 PolarHBondContact OD1-NZ 3.05Å; D532-M536 VanDerWaalsContact O-CG 3.29Å; D532-M536 WeakPolarHBondContact O-CG 3.29Å; D532-M536 PolarHBondContact O-N 3.26Å
533A89.6Confident88.8Confident0 Ų024.4 Ų24.40%013%0.127CC..Hα-helixtrans-57.7-40.5175.400000111.5W183 Y184 V529 C537W183-A533 HydrophobicContact CD2-CB 3.62Å; W183-A533 HydrophobicContact CE3-CB 4.04Å; W183-A533 HydrophobicContact CG-CB 4.02Å; W183-A533 HydrophobicContact CH2-CB 4.33Å; W183-A533 HydrophobicContact CZ2-CB 3.93Å; W183-A533 HydrophobicContact CZ3-CB 4.36Å; Y184-A533 HydrophobicContact CD1-CB 4.18Å; Y184-A533 HydrophobicContact CG-CB 4.41Å; V529-A533 VanDerWaalsContact O-CB 3.32Å; V529-A533 WeakPolarHBondContact O-CB 3.28Å; A533-C537 WeakPolarHBondContact O-CB 3.48Å; A533-C537 PolarHBondContact O-N 3Å; A533-C537 VanDerWaalsContact O-N 3.14Å; A533-C537 PolarHBondContact O-SG 3.33Å
534F87.5Confident88.9Confident31 Ų3120.4 Ų20.414%0.13611%0.105CC..Hα-helixtrans-66.8-45.7175.5177.9-91.3000112.5Y184 Y450 Y530 S531 D532 M536 C537 H538 V539Y184-F534 HydrophobicContact CE2-CD2 4.12Å; Y450-F534 AromaticContact CD2-CE1 3.86Å; Y450-F534 HydrophobicContact CD2-CE1 3.86Å; Y450-F534 AromaticContact CD2-CE2 3.75Å; Y450-F534 HydrophobicContact CD2-CE2 3.75Å; Y450-F534 AromaticContact CD2-CZ 3.36Å; Y450-F534 HydrophobicContact CD2-CZ 3.36Å; Y450-F534 HydrophobicContact CE2-CE2 4.21Å; Y450-F534 HydrophobicContact CE2-CZ 4.16Å; Y450-F534 HydrophobicContact CG-CE1 4.36Å; Y450-F534 HydrophobicContact CG-CZ 4.2Å; Y530-F534 WeakPolarHBondContact O-CB 3.42Å; Y530-F534 PolarHBondContact O-N 3.21Å; S531-F534 WeakPolarHBondContact O-CB 3.32Å; S531-F534 PolarHBondContact O-N 3.44Å; D532-F534 PolarHBondContact O-N 2.88Å; F534-M536 VanDerWaalsContact C-N 3.31Å; F534-M536 PolarHBondContact O-N 3.3Å; F534-C537 PolarHBondContact O-N 3.39Å; F534-H538 AromaticContact CD2-CD2 3.81Å; F534-H538 HydrophobicContact CE1-CB 4.42Å; F534-H538 HydrophobicContact CE2-CB 4.14Å; F534-H538 AromaticContact CE2-CD2 3.52Å; F534-H538 HydrophobicContact CZ-CB 4Å; F534-H538 PolarHBondContact O-N 3.43Å; F534-V539 HydrophobicContact CD1-CG2 4.42Å; F534-V539 HydrophobicContact CE1-CG2 4.06Å
535K86.8Confident89Confident13 Ų1320.2 Ų20.26%0.05711%0.105CC..Hα-helixtrans-55.4-47.6176.9-79.2-175.9-68.8-178.70110.4E445 E528 S531 D532 C537 H538 V539 F540E445-K535 HydrophobicContact CB-CD 4.33Å; E445-K535 WeakPolarHBondContact O-CD 3.45Å; E445-K535 WeakPolarHBondContact O-CG 3.37Å; E445-K535 IonicContact OE2-NZ 2.8Å; E445-K535 PolarHBondContact OE2-NZ 3.35Å; E528-K535 IonicContact OE1-NZ 3.71Å; S531-K535 WeakPolarHBondContact O-CG 3.4Å; S531-K535 PolarHBondContact O-N 3.31Å; D532-K535 PolarHBondContact O-N 2.92Å; D532-K535 WeakPolarHBondContact OD1-CE 3.33Å; D532-K535 IonicContact OD1-NZ 3.72Å; D532-K535 PolarHBondContact OD1-NZ 3.05Å; K535-C537 PolarHBondContact O-N 2.99Å; K535-H538 PolarHBondContact O-N 3.18Å; K535-V539 HydrophobicContact CG-CG2 4.48Å; K535-V539 WeakPolarHBondContact O-CA 3.44Å; K535-V539 WeakPolarHBondContact O-CB 3.42Å; K535-V539 PolarHBondContact O-N 3.46Å; K535-F540 HydrophobicContact CB-CD2 4.16Å; K535-F540 HydrophobicContact CB-CE2 3.93Å; K535-F540 HydrophobicContact CD-CE2 4.29Å; K535-F540 HydrophobicContact CG-CE2 4.44Å; K535-F540 PolarHBondContact O-N 2.9Å; K535-F540 VanDerWaalsContact O-N 3.15Å
536M88.3Confident88.6Confident7 Ų724 Ų243%0.03412%0.124CC..Hα-helixtrans-66.3-34.4-179.5-67.6-63.5-75.800113.3W183 Y201 Q205 F209 Y490 D532 F534 F540 P543W183-M536 HydrophobicContact CH2-CB 4.49Å; Y201-M536 HydrophobicContact CD1-CE 3.82Å; Y201-M536 HydrophobicContact CE1-CB 4.47Å; Y201-M536 HydrophobicContact CE1-CE 3.95Å; Y201-M536 HydrophobicContact CG-CE 4.29Å; Y201-M536 PolarHBondContact OH-O 3.42Å; Q205-M536 HydrophobicContact CG-CE 4.07Å; F209-M536 HydrophobicContact CE2-CG 4.29Å; F209-M536 HydrophobicContact CZ-CG 4.17Å; Y490-M536 HydrophobicContact CD1-SD 4.45Å; Y490-M536 HydrophobicContact CD2-SD 3.94Å; Y490-M536 HydrophobicContact CE1-CE 4.44Å; Y490-M536 HydrophobicContact CE1-SD 4.4Å; Y490-M536 HydrophobicContact CE2-SD 3.93Å; Y490-M536 HydrophobicContact CG-SD 4.2Å; D532-M536 VanDerWaalsContact O-CG 3.29Å; D532-M536 WeakPolarHBondContact O-CG 3.29Å; D532-M536 PolarHBondContact O-N 3.26Å; F534-M536 VanDerWaalsContact C-N 3.31Å; F534-M536 PolarHBondContact O-N 3.3Å; M536-F540 HydrophobicContact SD-CD2 4.43Å; M536-P543 HydrophobicContact CE-CG 3.77Å
537C88.2Confident88.5Confident4 Ų423.4 Ų23.43%0.02712%0.122CC..Hα-helixtrans-81.9-28-179.1-69.10000114L176 Y184 A533 F534 K535L176-C537 HydrophobicContact CD1-CB 4.18Å; L176-C537 WeakPolarHBondContact CD2-O 3.37Å; Y184-C537 HydrophobicContact CE1-CB 4.22Å; A533-C537 WeakPolarHBondContact O-CB 3.48Å; A533-C537 PolarHBondContact O-N 3Å; A533-C537 VanDerWaalsContact O-N 3.14Å; A533-C537 PolarHBondContact O-SG 3.33Å; F534-C537 PolarHBondContact O-N 3.39Å; K535-C537 PolarHBondContact O-N 2.99Å
538H82.8Confident88.6Confident59 Ų5921.7 Ų21.727%0.27311%0.114SC..Hα-helixtrans-134.5-18.8-165.5-72.8-44000115.6Y184 Q453 F534 K535Y184-H538 PolarHBondContact OH-CD2 3.12Å; Y184-H538 VanDerWaalsContact OH-CD2 3.27Å; Y184-H538 PolarHBondContact OH-NE2 2.81Å; Q453-H538 HydrophobicContact CG-CB 4.42Å; Q453-H538 PolarHBondContact NE2-O 2.89Å; Q453-H538 PolarHBondContact OE1-O 2.94Å; F534-H538 AromaticContact CD2-CD2 3.81Å; F534-H538 HydrophobicContact CE1-CB 4.42Å; F534-H538 HydrophobicContact CE2-CB 4.14Å; F534-H538 AromaticContact CE2-CD2 3.52Å; F534-H538 HydrophobicContact CZ-CB 4Å; F534-H538 PolarHBondContact O-N 3.43Å; K535-H538 PolarHBondContact O-N 3.18Å
539V83.9Confident88.6Confident17 Ų1722.8 Ų22.810%0.10312%0.123CC..THydrogen-bonded Turntrans-101.6-48.1-174.8178.80000110.8P449 M487 S488 F534 K535P449-V539 HydrophobicContact CB-CB 4.47Å; P449-V539 HydrophobicContact CB-CG1 3.98Å; P449-V539 HydrophobicContact CB-CG2 3.64Å; M487-V539 VanDerWaalsContact CE-C 3.48Å; M487-V539 VanDerWaalsContact CE-O 3.23Å; M487-V539 WeakPolarHBondContact CE-O 3.44Å; S488-V539 PolarHBondContact OG-O 3.16Å; F534-V539 HydrophobicContact CD1-CG2 4.42Å; F534-V539 HydrophobicContact CE1-CG2 4.06Å; K535-V539 HydrophobicContact CG-CG2 4.48Å; K535-V539 WeakPolarHBondContact O-CA 3.44Å; K535-V539 WeakPolarHBondContact O-CB 3.42Å; K535-V539 PolarHBondContact O-N 3.46Å
540F88.1Confident88.8Confident44 Ų4425.7 Ų25.719%0.19314%0.138CC..BIsolated β-bridgetrans-93.8152.3-175.3-62.5-61.3000113.2M487 S488 Y490 K535 M536M487-F540 WeakPolarHBondContact CE-O 3.44Å; S488-F540 CarbonylContact O-C 3.2Å; S488-F540 VanDerWaalsContact O-CA 3.32Å; S488-F540 WeakPolarHBondContact O-CA 3.48Å; S488-F540 VanDerWaalsContact OG-CD1 3.23Å; S488-F540 WeakPolarHBondContact OG-CD1 3.34Å; Y490-F540 AromaticContact CD2-CD2 3.78Å; Y490-F540 HydrophobicContact CD2-CD2 3.78Å; Y490-F540 AromaticContact CD2-CE2 3.85Å; Y490-F540 HydrophobicContact CD2-CE2 3.85Å; Y490-F540 HydrophobicContact CD2-CG 4.26Å; Y490-F540 HydrophobicContact CD2-CZ 4.41Å; Y490-F540 HydrophobicContact CE2-CE2 4.5Å; Y490-F540 HydrophobicContact CG-CD2 4.48Å; K535-F540 HydrophobicContact CB-CD2 4.16Å; K535-F540 HydrophobicContact CB-CE2 3.93Å; K535-F540 HydrophobicContact CD-CE2 4.29Å; K535-F540 HydrophobicContact CG-CE2 4.44Å; K535-F540 PolarHBondContact O-N 2.9Å; K535-F540 VanDerWaalsContact O-N 3.15Å; M536-F540 HydrophobicContact SD-CD2 4.43Å
541K90.6Very high89Confident9 Ų923.7 Ų23.74%0.03913%0.131CC..PPolyproline II helixtrans-54.6153.6159.3-68.2171.6174.5141.80109.3F168 E484 A485 M487 S488 P543F168-K541 HydrophobicContact CB-CD 4.28Å; F168-K541 HydrophobicContact CG-CD 4.22Å; E484-K541 WeakPolarHBondContact O-CE 3.24Å; E484-K541 WeakPolarHBondContact O-CG 3.47Å; A485-K541 WeakPolarHBondContact O-CE 3.33Å; A485-K541 PolarHBondContact O-NZ 3.15Å; M487-K541 HydrophobicContact CB-CG 3.7Å; M487-K541 WeakPolarHBondContact O-CE 3.39Å; M487-K541 PolarHBondContact O-NZ 3.31Å; S488-K541 PolarHBondContact O-N 2.95Å; K541-P543 VanDerWaalsContact O-CD 3.29Å; K541-P543 WeakPolarHBondContact O-CD 3.34Å; K541-P543 VanDerWaalsContact O-N 3.16Å
542R94.1Very high89.2Confident4 Ų424.6 Ų24.62%0.01514%0.141CC..PPolyproline II helixtrans-58.2121.8169.9-170.6176.6-175.6175-2.8108.3M118 Q122 P169 L170 H171 Y200 Y201M118-R542 PolarHBondContact SD-NH1 2.87Å; Q122-R542 VanDerWaalsContact OE1-NE 3.1Å; Q122-R542 VanDerWaalsContact OE1-NH1 3.08Å; P169-R542 WeakPolarHBondContact CD-O 3.48Å; P169-R542 HydrophobicContact CG-CB 4.02Å; P169-R542 HydrophobicContact CG-CG 4.07Å; P169-R542 WeakPolarHBondContact CG-O 3.38Å; L170-R542 WeakPolarHBondContact O-CD 3.5Å; L170-R542 PolarHBondContact O-NH1 3.36Å; H171-R542 WeakPolarHBondContact NE2-CA 3.24Å; H171-R542 PolarHBondContact NE2-N 3.36Å; Y200-R542 VanDerWaalsContact O-CZ 3.3Å; Y200-R542 PolarHBondContact O-NE 3.14Å; Y200-R542 PolarHBondContact O-NH2 3.44Å; Y201-R542 HydrophobicContact CE1-CG 4.49Å
543P94.1Very high89.3Confident18 Ų1825.5 Ų25.512%0.11715%0.147CC..PPolyproline II helixtrans-71153.8169.430-34.3000109.8Y201 Q205 Y490 M536 K541Y201-P543 HydrophobicContact CD1-CG 3.98Å; Q205-P543 HydrophobicContact CG-CG 4.36Å; Y490-P543 HydrophobicContact CD1-CB 3.97Å; Y490-P543 HydrophobicContact CD1-CG 4.18Å; M536-P543 HydrophobicContact CE-CG 3.77Å; K541-P543 VanDerWaalsContact O-CD 3.29Å; K541-P543 WeakPolarHBondContact O-CD 3.34Å; K541-P543 VanDerWaalsContact O-N 3.16Å
544F93.3Very high89.5Confident24 Ų2426 Ų2611%0.10515%0.149CC..PPolyproline II helixtrans-66.2142.6166.7-75.3-74.7000110V16 K126 M167 P169 D546V16-F544 HydrophobicContact CG1-CE1 4.43Å; V16-F544 HydrophobicContact CG1-CZ 4.05Å; V16-F544 HydrophobicContact CG2-CE1 3.96Å; V16-F544 HydrophobicContact CG2-CZ 4.41Å; K126-F544 HydrophobicContact CB-CD1 3.8Å; K126-F544 HydrophobicContact CB-CE1 3.71Å; K126-F544 HydrophobicContact CB-CG 4.42Å; K126-F544 HydrophobicContact CB-CZ 4.23Å; K126-F544 HydrophobicContact CD-CB 3.62Å; K126-F544 HydrophobicContact CD-CD1 3.68Å; K126-F544 HydrophobicContact CD-CD2 3.77Å; K126-F544 HydrophobicContact CD-CE1 4.23Å; K126-F544 HydrophobicContact CD-CE2 4.28Å; K126-F544 HydrophobicContact CD-CG 3.42Å; K126-F544 VanDerWaalsContact CD-CG 3.42Å; K126-F544 HydrophobicContact CG-CD1 4.27Å; K126-F544 HydrophobicContact CG-CE1 4.38Å; K126-F544 HydrophobicContact CG-CG 4.4Å; M167-F544 HydrophobicContact CE-CE2 3.84Å; M167-F544 HydrophobicContact CE-CZ 3.98Å; M167-F544 HydrophobicContact CG-CE2 4.14Å; M167-F544 HydrophobicContact CG-CZ 3.88Å; M167-F544 WeakPolarHBondContact O-CE2 3.4Å; M167-F544 HydrophobicContact SD-CZ 4.4Å; P169-F544 HydrophobicContact CB-CD1 4.11Å; P169-F544 HydrophobicContact CB-CE1 3.89Å; P169-F544 HydrophobicContact CB-CZ 4.43Å; P169-F544 HydrophobicContact CG-CD1 3.8Å; P169-F544 HydrophobicContact CG-CD2 4.37Å; P169-F544 HydrophobicContact CG-CE1 3.9Å; P169-F544 HydrophobicContact CG-CE2 4.49Å; P169-F544 HydrophobicContact CG-CG 4.04Å; P169-F544 HydrophobicContact CG-CZ 4.25Å; F544-D546 PolarHBondContact O-N 3.16Å
545A91.7Very high89.9Confident6 Ų625.7 Ų25.75%0.0515%0.147CC..PPolyproline II helixtrans-65.8129.317300000109.6A119 Y123 Y201A119-A545 HydrophobicContact CB-CB 4.07Å; Y123-A545 WeakPolarHBondContact CD2-O 3.35Å; Y123-A545 WeakPolarHBondContact CE2-O 3.48Å; Y201-A545 WeakPolarHBondContact O-CA 3.44Å
546D83.8Confident90.2Very high78 Ų7830 Ų3042%0.41717%0.17SC..  trans-116.3114.3174.8-67.9-43.6000108.5K126 G204 F544 A548K126-D546 IonicContact NZ-OD1 2.82Å; K126-D546 PolarHBondContact NZ-OD1 2.99Å; K126-D546 VanDerWaalsContact NZ-OD1 3.14Å; G204-D546 PolarHBondContact N-O 3.27Å; F544-D546 PolarHBondContact O-N 3.16Å; D546-A548 PolarHBondContact O-N 3.45Å
547P87.6Confident90.5Very high35 Ų3530 Ų3023%0.22717%0.172CC..  trans-63.9122.6-180-27.538.2000111.3Y123 T271Y123-P547 HydrophobicContact CD1-CG 4.25Å; Y123-P547 HydrophobicContact CE1-CG 3.64Å; Y123-P547 HydrophobicContact CE2-CG 4.2Å; Y123-P547 VanDerWaalsContact CZ-CD 3.44Å; T271-P547 HydrophobicContact CG2-CB 4.2Å
548A88.9Confident90.9Very high26 Ų2629.9 Ų29.922%0.21517%0.171CC..  trans-133.1139.1-179.200000110.9L207 T271 D546L207-A548 HydrophobicContact CD1-CB 3.71Å; T271-A548 VanDerWaalsContact CB-O 3.3Å; T271-A548 WeakPolarHBondContact CB-O 3.47Å; T271-A548 PolarHBondContact OG1-O 3.01Å; D546-A548 PolarHBondContact O-N 3.45Å
549A90.8Very high91.5Very high23 Ų2329.4 Ų29.419%0.1917%0.169CC..SBendtrans-103-14.8177.200000112.9A266A266-A549 HydrophobicContact CB-CB 4.26Å; A266-A549 VanDerWaalsContact CB-O 3.24Å; A266-A549 WeakPolarHBondContact CB-O 3.36Å
550N92Very high92.1Very high79 Ų7931.8 Ų31.842%0.42218%0.184SC..SBendtrans-160.4175.4178.357.237.2000109.7G552N550-G552 PolarHBondContact O-N 3.35Å; N550-G552 VanDerWaalsContact O-N 3.15Å; N550-G552 WeakPolarHBondContact OD1-CA 3.49Å; N550-G552 PolarHBondContact OD1-N 2.95Å
551I91.9Very high92.4Very high8 Ų829.8 Ų29.84%0.04118%0.175CC..  trans-73.86.1177.566.1170.3000113.5F211 W258 Y497 W554 Q555 F558F211-I551 HydrophobicContact CB-CG2 4.44Å; F211-I551 HydrophobicContact CD2-CD1 4.46Å; F211-I551 HydrophobicContact CE2-CD1 4.27Å; F211-I551 HydrophobicContact CZ-CD1 4.5Å; W258-I551 HydrophobicContact CZ2-CG2 3.58Å; Y497-I551 HydrophobicContact CE1-CB 4.16Å; Y497-I551 HydrophobicContact CE1-CG2 3.97Å; Y497-I551 VanDerWaalsContact OH-CG2 3.3Å; Y497-I551 WeakPolarHBondContact OH-CG2 3.3Å; I551-W554 HydrophobicContact CB-CB 4.34Å; I551-W554 HydrophobicContact CD1-CB 3.91Å; I551-W554 HydrophobicContact CG1-CB 4.11Å; I551-W554 WeakPolarHBondContact O-CB 3.2Å; I551-W554 VanDerWaalsContact O-CD1 3.25Å; I551-Q555 HydrophobicContact CD1-CB 4.19Å; I551-Q555 HydrophobicContact CG1-CB 4.01Å; I551-F558 HydrophobicContact CD1-CD2 4.4Å
552G89.8Confident92.6Very high26 Ų2629.4 Ų29.427%0.26817%0.173SC..THydrogen-bonded Turntrans69.2-137.2176.900000113.8N550 W554 Q555N550-G552 PolarHBondContact O-N 3.35Å; N550-G552 VanDerWaalsContact O-N 3.15Å; N550-G552 WeakPolarHBondContact OD1-CA 3.49Å; N550-G552 PolarHBondContact OD1-N 2.95Å; G552-W554 PolarHBondContact O-N 2.95Å; G552-Q555 PolarHBondContact O-N 3.47Å
553V91.6Very high92.7Very high25 Ų2531.2 Ų31.215%0.15219%0.185CC..Hα-helixtrans-64.3-21.1-178.81690000112.8N395 V398 Q555 L556 A557N395-V553 HydrophobicContact CB-CG2 3.41Å; N395-V553 VanDerWaalsContact CB-CG2 3.41Å; N395-V553 WeakPolarHBondContact OD1-CG2 3.38Å; V398-V553 HydrophobicContact CG1-CB 4.38Å; V398-V553 HydrophobicContact CG1-CG1 4.18Å; V553-Q555 PolarHBondContact O-N 3.41Å; V553-L556 WeakPolarHBondContact O-CB 3.15Å; V553-L556 PolarHBondContact O-N 3.03Å; V553-L556 VanDerWaalsContact O-N 3.11Å; V553-A557 PolarHBondContact O-N 3.49Å
554W94.6Very high92.8Very high10 Ų1033 Ų334%0.03819%0.193CC..Hα-helixtrans-57.1-36.5177-66.4114.4000112.3V398 L402 F494 Y497 L498 F501 I551 G552 L556 A557 F558V398-W554 HydrophobicContact CG1-CD2 4.23Å; V398-W554 HydrophobicContact CG1-CH2 4.22Å; V398-W554 HydrophobicContact CG1-CZ2 3.79Å; L402-W554 HydrophobicContact CD1-CE3 3.79Å; L402-W554 HydrophobicContact CD1-CH2 4.11Å; L402-W554 HydrophobicContact CD1-CZ3 3.4Å; L402-W554 HydrophobicContact CG-CZ3 4.38Å; F494-W554 HydrophobicContact CD2-CH2 4.25Å; F494-W554 AromaticContact CD2-CZ2 3.55Å; F494-W554 HydrophobicContact CD2-CZ2 3.55Å; F494-W554 AromaticContact CE2-CH2 3.85Å; F494-W554 HydrophobicContact CE2-CH2 3.85Å; F494-W554 AromaticContact CE2-CZ2 3.59Å; F494-W554 HydrophobicContact CE2-CZ2 3.59Å; F494-W554 HydrophobicContact CG-CZ2 4.4Å; F494-W554 HydrophobicContact CZ-CH2 4.42Å; F494-W554 HydrophobicContact CZ-CZ2 4.49Å; F494-W554 WeakPolarHBondContact O-CZ2 3.49Å; Y497-W554 HydrophobicContact CD1-CG 4.35Å; Y497-W554 AromaticContact CD2-CD1 3.61Å; Y497-W554 HydrophobicContact CD2-CG 4.36Å; Y497-W554 AromaticContact CD2-NE1 3.57Å; Y497-W554 AromaticContact CG-CD1 3.68Å; Y497-W554 HydrophobicContact CG-CD2 4.18Å; Y497-W554 AromaticContact CG-CG 4Å; Y497-W554 HydrophobicContact CG-CG 4Å; Y497-W554 AromaticContact CG-NE1 3.72Å; L498-W554 VanDerWaalsContact CA-CH2 3.44Å; L498-W554 HydrophobicContact CB-CH2 3.69Å; L498-W554 HydrophobicContact CB-CZ2 4.44Å; L498-W554 HydrophobicContact CB-CZ3 4.42Å; L498-W554 HydrophobicContact CD1-CH2 4.08Å; L498-W554 HydrophobicContact CD1-CZ3 4.41Å; F501-W554 HydrophobicContact CB-CE3 4.2Å; F501-W554 HydrophobicContact CB-CZ3 3.82Å; F501-W554 HydrophobicContact CG-CZ3 4.12Å; I551-W554 HydrophobicContact CB-CB 4.34Å; I551-W554 HydrophobicContact CD1-CB 3.91Å; I551-W554 HydrophobicContact CG1-CB 4.11Å; I551-W554 WeakPolarHBondContact O-CB 3.2Å; I551-W554 VanDerWaalsContact O-CD1 3.25Å; G552-W554 PolarHBondContact O-N 2.95Å; W554-L556 PolarHBondContact O-N 3.1Å; W554-A557 WeakPolarHBondContact O-CB 3.26Å; W554-A557 PolarHBondContact O-N 3.25Å; W554-A557 VanDerWaalsContact O-N 3.09Å; W554-F558 HydrophobicContact CB-CD2 4.36Å; W554-F558 HydrophobicContact CB-CE2 4.29Å; W554-F558 WeakPolarHBondContact O-CD2 3.21Å; W554-F558 PolarHBondContact O-N 2.81Å
555Q94.6Very high92.8Very high24 Ų2432 Ų3211%0.11219%0.189CC..Hα-helixtrans-56.4-50.7175.5-177.464.633.300111.5L255 K259 I551 G552 V553 A557 F558 E559L255-Q555 PolarHBondContact O-NE2 2.76Å; K259-Q555 HydrophobicContact CD-CG 4.17Å; K259-Q555 HydrophobicContact CG-CG 4.18Å; I551-Q555 HydrophobicContact CD1-CB 4.19Å; I551-Q555 HydrophobicContact CG1-CB 4.01Å; G552-Q555 PolarHBondContact O-N 3.47Å; V553-Q555 PolarHBondContact O-N 3.41Å; Q555-A557 VanDerWaalsContact C-N 3.26Å; Q555-A557 PolarHBondContact O-N 3.42Å; Q555-F558 PolarHBondContact O-N 2.93Å; Q555-E559 PolarHBondContact NE2-OE1 2.92Å; Q555-E559 WeakPolarHBondContact O-CB 3.42Å; Q555-E559 WeakPolarHBondContact O-CG 3.42Å; Q555-E559 PolarHBondContact O-N 2.93Å
556L93.6Very high92.9Very high103 Ų10331.8 Ų31.854%0.53919%0.187SC..Hα-helixtrans-62-37.7177.817763.5000111.2V553 W554 T560V553-L556 WeakPolarHBondContact O-CB 3.15Å; V553-L556 PolarHBondContact O-N 3.03Å; V553-L556 VanDerWaalsContact O-N 3.11Å; W554-L556 PolarHBondContact O-N 3.1Å; L556-T560 VanDerWaalsContact O-CB 3.31Å; L556-T560 WeakPolarHBondContact O-CB 3.45Å; L556-T560 PolarHBondContact O-N 2.93Å; L556-T560 PolarHBondContact O-OG1 3.38Å
557A95.6Very high93.4Very high9 Ų931.3 Ų31.37%0.07419%0.187CC..Hα-helixtrans-64.6-50.317800000112L402 F501 V553 W554 Q555 E559 T560 M561L402-A557 HydrophobicContact CD1-CB 3.36Å; L402-A557 HydrophobicContact CD2-CB 4.36Å; F501-A557 HydrophobicContact CD2-CB 4.08Å; F501-A557 HydrophobicContact CE2-CB 3.75Å; F501-A557 WeakPolarHBondContact CE2-O 3.46Å; F501-A557 HydrophobicContact CZ-CB 4.39Å; V553-A557 PolarHBondContact O-N 3.49Å; W554-A557 WeakPolarHBondContact O-CB 3.26Å; W554-A557 PolarHBondContact O-N 3.25Å; W554-A557 VanDerWaalsContact O-N 3.09Å; Q555-A557 VanDerWaalsContact C-N 3.26Å; Q555-A557 PolarHBondContact O-N 3.42Å; A557-E559 VanDerWaalsContact C-N 3.33Å; A557-E559 PolarHBondContact O-N 2.76Å; A557-T560 PolarHBondContact O-N 2.85Å; A557-M561 WeakPolarHBondContact O-CB 3.17Å; A557-M561 PolarHBondContact O-N 3.36Å
558F96.3Very high93.7Very high0 Ų029.9 Ų29.90%018%0.178CC..Hα-helixtrans-60.1-41.4176.5-79.1-76.9000112F211 L255 L500 F501 F504 I551 W554 Q555 M561 S562F211-F558 HydrophobicContact CE1-CD2 4.43Å; F211-F558 HydrophobicContact CE1-CE1 4.36Å; F211-F558 AromaticContact CE1-CE2 3.57Å; F211-F558 HydrophobicContact CE1-CE2 3.57Å; F211-F558 AromaticContact CE1-CZ 3.55Å; F211-F558 HydrophobicContact CE1-CZ 3.55Å; F211-F558 AromaticContact CZ-CD2 3.96Å; F211-F558 HydrophobicContact CZ-CD2 3.96Å; F211-F558 HydrophobicContact CZ-CE1 4.12Å; F211-F558 AromaticContact CZ-CE2 3.54Å; F211-F558 HydrophobicContact CZ-CE2 3.54Å; F211-F558 HydrophobicContact CZ-CG 4.48Å; F211-F558 AromaticContact CZ-CZ 3.65Å; F211-F558 HydrophobicContact CZ-CZ 3.65Å; L255-F558 HydrophobicContact CD1-CB 4.1Å; L255-F558 WeakPolarHBondContact CD1-O 3.26Å; L255-F558 HydrophobicContact CD2-CB 3.6Å; L255-F558 HydrophobicContact CD2-CG 4.22Å; L500-F558 HydrophobicContact CB-CZ 4.22Å; F501-F558 HydrophobicContact CB-CE1 4.23Å; F501-F558 HydrophobicContact CB-CE2 4.45Å; F501-F558 HydrophobicContact CB-CZ 3.91Å; F501-F558 HydrophobicContact CD2-CD1 4.29Å; F501-F558 HydrophobicContact CD2-CE1 4.33Å; F501-F558 HydrophobicContact CD2-CG 4.43Å; F501-F558 HydrophobicContact CD2-CZ 4.49Å; F504-F558 HydrophobicContact CB-CD1 3.98Å; F504-F558 HydrophobicContact CB-CE1 3.65Å; F504-F558 AromaticContact CD1-CD1 3.48Å; F504-F558 HydrophobicContact CD1-CD1 3.48Å; F504-F558 VanDerWaalsContact CD1-CD1 3.48Å; F504-F558 HydrophobicContact CD1-CE1 4.08Å; F504-F558 HydrophobicContact CE1-CD1 4.1Å; F504-F558 AromaticContact CG-CD1 3.8Å; F504-F558 HydrophobicContact CG-CD1 3.8Å; F504-F558 AromaticContact CG-CE1 3.99Å; F504-F558 HydrophobicContact CG-CE1 3.99Å; I551-F558 HydrophobicContact CD1-CD2 4.4Å; W554-F558 HydrophobicContact CB-CD2 4.36Å; W554-F558 HydrophobicContact CB-CE2 4.29Å; W554-F558 WeakPolarHBondContact O-CD2 3.21Å; W554-F558 PolarHBondContact O-N 2.81Å; Q555-F558 PolarHBondContact O-N 2.93Å; F558-M561 PolarHBondContact O-N 3.32Å; F558-S562 WeakPolarHBondContact O-CB 3.2Å; F558-S562 PolarHBondContact O-N 2.84Å
559E95.4Very high93.8Very high49 Ų4928.8 Ų28.823%0.22917%0.168CC..Hα-helixtrans-62.5-44.2175.1-74.3172-178.100111.7L255 K259 Q555 A557 S562 V563L255-E559 HydrophobicContact CD1-CG 4.14Å; K259-E559 IonicContact NZ-OE1 2.7Å; Q555-E559 PolarHBondContact NE2-OE1 2.92Å; Q555-E559 WeakPolarHBondContact O-CB 3.42Å; Q555-E559 WeakPolarHBondContact O-CG 3.42Å; Q555-E559 PolarHBondContact O-N 2.93Å; A557-E559 VanDerWaalsContact C-N 3.33Å; A557-E559 PolarHBondContact O-N 2.76Å; E559-S562 WeakPolarHBondContact O-CB 3.48Å; E559-S562 PolarHBondContact O-N 2.88Å; E559-V563 WeakPolarHBondContact O-CG2 3.23Å; E559-V563 PolarHBondContact O-N 3.35Å
560T95.3Very high93.9Very high67 Ų6728.3 Ų28.341%0.41116%0.163SC..Hα-helixtrans-63.1-45.1176.9-57.40000111.2L556 A557 S562 V563 I564L556-T560 VanDerWaalsContact O-CB 3.31Å; L556-T560 WeakPolarHBondContact O-CB 3.45Å; L556-T560 PolarHBondContact O-N 2.93Å; L556-T560 PolarHBondContact O-OG1 3.38Å; A557-T560 PolarHBondContact O-N 2.85Å; T560-S562 VanDerWaalsContact C-N 3.27Å; T560-S562 PolarHBondContact O-N 2.93Å; T560-V563 WeakPolarHBondContact O-CB 3.4Å; T560-V563 PolarHBondContact O-N 2.7Å; T560-V563 VanDerWaalsContact O-N 3.11Å; T560-I564 HydrophobicContact CG2-CD1 4.08Å; T560-I564 WeakPolarHBondContact O-CG1 3.33Å; T560-I564 PolarHBondContact O-N 2.83Å
561M95.6Very high93.8Very high2 Ų226 Ų261%0.0116%0.155CC..Hα-helixtrans-56.6-43.9173.6179.269.278.400111F406 F410 F501 F504 G505 L509 A557 F558 V563 I564 A565F406-M561 HydrophobicContact CD2-CE 3.45Å; F406-M561 VanDerWaalsContact CD2-CE 3.45Å; F406-M561 HydrophobicContact CD2-SD 4.37Å; F406-M561 HydrophobicContact CE2-CE 3.35Å; F406-M561 HydrophobicContact CE2-SD 3.66Å; F410-M561 HydrophobicContact CE2-CE 3.88Å; F410-M561 HydrophobicContact CZ-CE 4.33Å; F501-M561 HydrophobicContact CD1-CE 4.43Å; F501-M561 HydrophobicContact CD2-CE 4.5Å; F501-M561 HydrophobicContact CE1-CE 3.72Å; F501-M561 HydrophobicContact CE2-CB 3.87Å; F501-M561 HydrophobicContact CE2-CE 3.79Å; F501-M561 HydrophobicContact CZ-CB 4.37Å; F501-M561 HydrophobicContact CZ-CE 3.37Å; F504-M561 HydrophobicContact CD1-CB 4.12Å; F504-M561 HydrophobicContact CD1-CG 3.67Å; F504-M561 HydrophobicContact CE1-CB 4.08Å; F504-M561 HydrophobicContact CE1-CG 3.85Å; G505-M561 VanDerWaalsContact CA-SD 3.59Å; L509-M561 HydrophobicContact CD1-SD 3.68Å; L509-M561 HydrophobicContact CD2-SD 3.9Å; L509-M561 HydrophobicContact CG-SD 3.72Å; A557-M561 WeakPolarHBondContact O-CB 3.17Å; A557-M561 PolarHBondContact O-N 3.36Å; F558-M561 PolarHBondContact O-N 3.32Å; M561-V563 VanDerWaalsContact C-N 3.32Å; M561-V563 PolarHBondContact O-N 3.13Å; M561-I564 PolarHBondContact O-N 2.95Å; M561-A565 WeakPolarHBondContact O-CB 3.39Å; M561-A565 PolarHBondContact O-N 3.13Å
562S95.1Very high93.7Very high1 Ų125.9 Ų25.91%0.00716%0.155CC..Hα-helixtrans-66-31.8177.7-177.70000113F558 E559 T560 V566 K605F558-S562 WeakPolarHBondContact O-CB 3.2Å; F558-S562 PolarHBondContact O-N 2.84Å; E559-S562 WeakPolarHBondContact O-CB 3.48Å; E559-S562 PolarHBondContact O-N 2.88Å; T560-S562 VanDerWaalsContact C-N 3.27Å; T560-S562 PolarHBondContact O-N 2.93Å; S562-V566 WeakPolarHBondContact O-CG2 3.3Å; S562-V566 PolarHBondContact O-N 3.47Å; S562-K605 PolarHBondContact OG-NZ 3.28Å
563V95.6Very high93.5Very high42 Ų4225.9 Ų25.926%0.25515%0.148SC..Hα-helixtrans-68.6-46.4171.7172.30000110.7E559 T560 M561 A565 V566 L602 K605 F606E559-V563 WeakPolarHBondContact O-CG2 3.23Å; E559-V563 PolarHBondContact O-N 3.35Å; T560-V563 WeakPolarHBondContact O-CB 3.4Å; T560-V563 PolarHBondContact O-N 2.7Å; T560-V563 VanDerWaalsContact O-N 3.11Å; M561-V563 VanDerWaalsContact C-N 3.32Å; M561-V563 PolarHBondContact O-N 3.13Å; V563-A565 PolarHBondContact O-N 2.68Å; V563-V566 WeakPolarHBondContact O-CB 3.42Å; V563-V566 PolarHBondContact O-N 3.26Å; V563-V566 VanDerWaalsContact O-N 3.13Å; V563-L602 HydrophobicContact CG1-CD2 4.04Å; V563-K605 HydrophobicContact CG2-CD 4.26Å; V563-F606 HydrophobicContact CG2-CZ 4.48Å
564I95.4Very high93.4Very high56 Ų5625 Ų2529%0.28715%0.145SC..Hα-helixtrans-59.7-39.2176.4-62.8167.4000110.2F406 F414 L509 T560 M561 V566 V567 T568F406-I564 HydrophobicContact CZ-CD1 4.12Å; F414-I564 HydrophobicContact CZ-CG2 4.31Å; L509-I564 HydrophobicContact CD2-CB 4.2Å; L509-I564 HydrophobicContact CD2-CG2 3.66Å; T560-I564 HydrophobicContact CG2-CD1 4.08Å; T560-I564 WeakPolarHBondContact O-CG1 3.33Å; T560-I564 PolarHBondContact O-N 2.83Å; M561-I564 PolarHBondContact O-N 2.95Å; I564-V566 VanDerWaalsContact C-N 3.29Å; I564-V566 PolarHBondContact O-N 3.48Å; I564-V567 PolarHBondContact O-N 2.94Å; I564-V567 VanDerWaalsContact O-N 3.16Å; I564-T568 PolarHBondContact O-N 3.42Å; I564-T568 PolarHBondContact O-OG1 2.67Å
565A94.4Very high92.9Very high4 Ų426.4 Ų26.43%0.03315%0.152CC..Hα-helixtrans-59.3-35.5176.700000113.5S508 L509 M561 V563 T568 N569S508-A565 WeakPolarHBondContact O-CB 3.31Å; L509-A565 HydrophobicContact CD2-CB 4.16Å; M561-A565 WeakPolarHBondContact O-CB 3.39Å; M561-A565 PolarHBondContact O-N 3.13Å; V563-A565 PolarHBondContact O-N 2.68Å; A565-T568 PolarHBondContact O-N 3.48Å; A565-N569 WeakPolarHBondContact O-CB 3.16Å; A565-N569 PolarHBondContact O-N 2.91Å; A565-N569 PolarHBondContact O-ND2 3.31Å
566V94Very high92.4Very high0 Ų026.2 Ų26.20%015%0.153CC..Hα-helixtrans-60.7-49.5175.1177.20000110V248 S562 V563 I564 C570 L601 L602 K605V248-V566 HydrophobicContact CB-CG2 4.34Å; V248-V566 HydrophobicContact CG1-CG2 3.64Å; V248-V566 HydrophobicContact CG2-CB 4.44Å; V248-V566 HydrophobicContact CG2-CG2 3.78Å; S562-V566 WeakPolarHBondContact O-CG2 3.3Å; S562-V566 PolarHBondContact O-N 3.47Å; V563-V566 WeakPolarHBondContact O-CB 3.42Å; V563-V566 PolarHBondContact O-N 3.26Å; V563-V566 VanDerWaalsContact O-N 3.13Å; I564-V566 VanDerWaalsContact C-N 3.29Å; I564-V566 PolarHBondContact O-N 3.48Å; V566-C570 WeakPolarHBondContact O-CB 3.34Å; V566-C570 PolarHBondContact O-N 3.26Å; V566-C570 PolarHBondContact O-SG 3.41Å; V566-L601 HydrophobicContact CG1-CB 3.9Å; V566-L602 HydrophobicContact CB-CD2 3.87Å; V566-L602 HydrophobicContact CG1-CD2 3.85Å; V566-L602 HydrophobicContact CG1-CG 4.07Å; V566-L602 HydrophobicContact CG2-CD2 4.07Å; V566-K605 HydrophobicContact CG2-CD 4.23Å
567V94.1Very high91.9Very high69 Ų6926.3 Ų26.342%0.41816%0.16SC..Hα-helixtrans-61.9-47.2179.5-177.40000110.6I564 C570 A571 E598I564-V567 PolarHBondContact O-N 2.94Å; I564-V567 VanDerWaalsContact O-N 3.16Å; V567-C570 PolarHBondContact O-N 2.85Å; V567-A571 WeakPolarHBondContact O-CB 3.36Å; V567-A571 PolarHBondContact O-N 3.02Å; V567-E598 HydrophobicContact CG2-CG 4.44Å
568T93.7Very high91.3Very high5 Ų529 Ų293%0.03117%0.171CC..Hα-helixtrans-61.2-49.9-179.4-55.80000111.9F414 F418 L509 F510 I564 A565 C570 A571 L572F414-T568 HydrophobicContact CE1-CG2 3.93Å; F418-T568 HydrophobicContact CE2-CG2 4.3Å; F418-T568 HydrophobicContact CZ-CG2 3.9Å; L509-T568 HydrophobicContact CB-CG2 4.36Å; L509-T568 WeakPolarHBondContact O-CG2 3.45Å; F510-T568 HydrophobicContact CE1-CG2 4.26Å; I564-T568 PolarHBondContact O-N 3.42Å; I564-T568 PolarHBondContact O-OG1 2.67Å; A565-T568 PolarHBondContact O-N 3.48Å; T568-C570 PolarHBondContact O-N 3.03Å; T568-A571 PolarHBondContact O-N 3.47Å; T568-L572 HydrophobicContact CG2-CD1 3.96Å; T568-L572 HydrophobicContact CG2-CG 4.46Å; T568-L572 WeakPolarHBondContact O-CB 3.12Å; T568-L572 VanDerWaalsContact O-CG 3.26Å; T568-L572 WeakPolarHBondContact O-CG 3.45Å; T568-L572 PolarHBondContact O-N 3.34Å
569N91.3Very high90.7Very high3 Ų329.3 Ų29.32%0.01617%0.173CC..Hα-helixtrans-66.5-38.8-179.4-72.1-78.3000111.6A244 S508 S511 C512 A565 L572 I573A244-N569 HydrophobicContact CB-CB 4.44Å; S508-N569 PolarHBondContact O-ND2 3.45Å; S511-N569 PolarHBondContact OG-OD1 3.27Å; C512-N569 PolarHBondContact SG-OD1 3.05Å; A565-N569 WeakPolarHBondContact O-CB 3.16Å; A565-N569 PolarHBondContact O-N 2.91Å; A565-N569 PolarHBondContact O-ND2 3.31Å; N569-L572 PolarHBondContact O-N 3.5Å; N569-I573 WeakPolarHBondContact O-CB 3.18Å; N569-I573 VanDerWaalsContact O-CG1 3.29Å; N569-I573 WeakPolarHBondContact O-CG1 3.13Å; N569-I573 PolarHBondContact O-N 3.4Å
570C91.3Very high90.2Very high12 Ų1231 Ų318%0.08118%0.18CC..Hα-helixtrans-63.6-42.7176-67.50000111.9V566 V567 T568 I573 G574 T594 E598V566-C570 WeakPolarHBondContact O-CB 3.34Å; V566-C570 PolarHBondContact O-N 3.26Å; V566-C570 PolarHBondContact O-SG 3.41Å; V567-C570 PolarHBondContact O-N 2.85Å; T568-C570 PolarHBondContact O-N 3.03Å; C570-I573 PolarHBondContact O-N 3.47Å; C570-G574 PolarHBondContact O-N 3.26Å; C570-T594 HydrophobicContact CB-CG2 4.36Å; C570-T594 WeakPolarHBondContact O-CG2 3.29Å; C570-E598 HydrophobicContact CB-CB 3.94Å; C570-E598 HydrophobicContact CB-CG 4.26Å
571A91.1Very high89.8Confident30 Ų3031.3 Ų31.325%0.24819%0.189CC..Hα-helixtrans-64.1-45.2176.700000111.8F418 V567 T568 I573 G574 M575F418-A571 HydrophobicContact CD1-CB 4.43Å; F418-A571 HydrophobicContact CE1-CB 3.52Å; F418-A571 HydrophobicContact CZ-CB 3.94Å; V567-A571 WeakPolarHBondContact O-CB 3.36Å; V567-A571 PolarHBondContact O-N 3.02Å; T568-A571 PolarHBondContact O-N 3.47Å; A571-I573 PolarHBondContact O-N 3.23Å; A571-G574 PolarHBondContact O-N 2.85Å; A571-M575 WeakPolarHBondContact O-CB 3.3Å; A571-M575 VanDerWaalsContact O-CG 3.24Å; A571-M575 WeakPolarHBondContact O-CG 3.42Å; A571-M575 PolarHBondContact O-N 2.98Å
572L89Confident89.3Confident7 Ų738.4 Ų38.44%0.03722%0.216CC..Hα-helixtrans-59.7-44.4176.7-72.9170.8000112.1A417 F418 M423 L426 F510 V513 T568 N569 M575 S576A417-L572 HydrophobicContact CB-CD2 4.06Å; F418-L572 HydrophobicContact CE1-CD2 4.17Å; F418-L572 HydrophobicContact CE1-CG 4.23Å; F418-L572 HydrophobicContact CZ-CG 4.4Å; M423-L572 HydrophobicContact CE-CD2 3.87Å; M423-L572 HydrophobicContact SD-CD2 4.05Å; L426-L572 HydrophobicContact CD2-CD2 4.3Å; F510-L572 HydrophobicContact CD1-CD1 4.25Å; V513-L572 HydrophobicContact CG2-CD1 3.98Å; V513-L572 HydrophobicContact CG2-CD2 4.32Å; T568-L572 HydrophobicContact CG2-CD1 3.96Å; T568-L572 HydrophobicContact CG2-CG 4.46Å; T568-L572 WeakPolarHBondContact O-CB 3.12Å; T568-L572 VanDerWaalsContact O-CG 3.26Å; T568-L572 WeakPolarHBondContact O-CG 3.45Å; T568-L572 PolarHBondContact O-N 3.34Å; N569-L572 PolarHBondContact O-N 3.5Å; L572-M575 PolarHBondContact O-N 3.02Å; L572-S576 PolarHBondContact O-N 2.85Å
573I87.1Confident88.9Confident25 Ų2541 Ų4113%0.12823%0.228CC..Hα-helixtrans-62.5-47.5176.1-70.8165000110.7Y237 V241 A244 N569 C570 A571 M575 S576 V579Y237-I573 HydrophobicContact CD2-CG2 4.45Å; Y237-I573 HydrophobicContact CE2-CG2 3.8Å; V241-I573 HydrophobicContact CG2-CG2 4.2Å; A244-I573 HydrophobicContact CB-CD1 3.5Å; A244-I573 VanDerWaalsContact CB-CD1 3.5Å; N569-I573 WeakPolarHBondContact O-CB 3.18Å; N569-I573 VanDerWaalsContact O-CG1 3.29Å; N569-I573 WeakPolarHBondContact O-CG1 3.13Å; N569-I573 PolarHBondContact O-N 3.4Å; C570-I573 PolarHBondContact O-N 3.47Å; A571-I573 PolarHBondContact O-N 3.23Å; I573-M575 PolarHBondContact O-N 3.01Å; I573-S576 WeakPolarHBondContact O-CB 3.28Å; I573-S576 PolarHBondContact O-N 2.79Å; I573-S576 VanDerWaalsContact O-N 3.09Å; I573-S576 PolarHBondContact O-OG 2.86Å; I573-V579 HydrophobicContact CG2-CG2 4.01Å; I573-V579 VanDerWaalsContact O-CG2 3.29Å; I573-V579 WeakPolarHBondContact O-CG2 3.29Å
574G87.5Confident88.4Confident8 Ų844.1 Ų44.18%0.08225%0.249CC..Hα-helixtrans-61.9-26.7179.400000113.6C570 A571C570-G574 PolarHBondContact O-N 3.26Å; A571-G574 PolarHBondContact O-N 2.85Å
575M85.7Confident87.8Confident39 Ų3950.7 Ų50.719%0.19228%0.278CS..Hα-helixtrans-85.4-12.5178.1-6917668.800113.9F418 Q421 A571 L572 I573 K580F418-M575 HydrophobicContact CD1-SD 3.68Å; F418-M575 HydrophobicContact CE1-SD 4.2Å; Q421-M575 HydrophobicContact CB-CE 4.23Å; Q421-M575 HydrophobicContact CG-CE 3.45Å; Q421-M575 VanDerWaalsContact CG-CE 3.45Å; A571-M575 WeakPolarHBondContact O-CB 3.3Å; A571-M575 VanDerWaalsContact O-CG 3.24Å; A571-M575 WeakPolarHBondContact O-CG 3.42Å; A571-M575 PolarHBondContact O-N 2.98Å; L572-M575 PolarHBondContact O-N 3.02Å; I573-M575 PolarHBondContact O-N 3.01Å; M575-K580 VanDerWaalsContact O-CE 3.29Å; M575-K580 WeakPolarHBondContact O-CE 3.32Å; M575-K580 PolarHBondContact O-NZ 3.49Å
576S83.9Confident87.6Confident19 Ų1952.1 Ų52.113%0.13329%0.288CS..SBendtrans-63.2143.4-178.771.40000112.1L572 I573 Q578 V579 K580L572-S576 PolarHBondContact O-N 2.85Å; I573-S576 WeakPolarHBondContact O-CB 3.28Å; I573-S576 PolarHBondContact O-N 2.79Å; I573-S576 VanDerWaalsContact O-N 3.09Å; I573-S576 PolarHBondContact O-OG 2.86Å; S576-Q578 PolarHBondContact O-N 3.28Å; S576-V579 PolarHBondContact O-N 2.92Å; S576-V579 VanDerWaalsContact OG-CG2 3.22Å; S576-V579 WeakPolarHBondContact OG-CG2 3.1Å; S576-V579 PolarHBondContact OG-N 3.47Å; S576-K580 PolarHBondContact O-N 2.97Å; S576-K580 VanDerWaalsContact O-N 3.14Å
577P83.3Confident87.3Confident106 Ų10659.6 Ų59.669%0.68832%0.323SS*.Hα-helixtrans-57.8-33.4179.4-25.534.2000113.4K580 A581P577-K580 PolarHBondContact O-N 2.84Å; P577-A581 PolarHBondContact O-N 2.92Å
578Q82.4Confident87.1Confident66 Ų6660.7 Ų60.731%0.30833%0.33SS..Hα-helixtrans-66.4-41-178.9-61.7158.2-5.500111.7E235 S576 A581 Y582E235-Q578 VanDerWaalsContact O-CD 3.29Å; E235-Q578 PolarHBondContact O-NE2 3.44Å; E235-Q578 PolarHBondContact O-OE1 3.49Å; E235-Q578 VanDerWaalsContact O-OE1 3.06Å; S576-Q578 PolarHBondContact O-N 3.28Å; Q578-A581 WeakPolarHBondContact O-CB 3.35Å; Q578-A581 PolarHBondContact O-N 2.78Å; Q578-Y582 WeakPolarHBondContact O-CD2 3.49Å
579V83.5Confident87Confident6 Ų665.4 Ų65.44%0.03635%0.352CS..Hα-helixtrans-72.7-40.9177.5-178.20000111.3Y237 I573 S576 A581 Y582 L590Y237-V579 HydrophobicContact CD2-CG2 3.18Å; Y237-V579 HydrophobicContact CE2-CB 4.4Å; Y237-V579 HydrophobicContact CE2-CG2 3.04Å; Y237-V579 HydrophobicContact CG-CG2 4.19Å; I573-V579 HydrophobicContact CG2-CG2 4.01Å; I573-V579 VanDerWaalsContact O-CG2 3.29Å; I573-V579 WeakPolarHBondContact O-CG2 3.29Å; S576-V579 PolarHBondContact O-N 2.92Å; S576-V579 VanDerWaalsContact OG-CG2 3.22Å; S576-V579 WeakPolarHBondContact OG-CG2 3.1Å; S576-V579 PolarHBondContact OG-N 3.47Å; V579-A581 PolarHBondContact O-N 2.69Å; V579-Y582 WeakPolarHBondContact O-CB 3.27Å; V579-Y582 PolarHBondContact O-N 3.38Å; V579-L590 HydrophobicContact CG1-CD1 3.44Å; V579-L590 VanDerWaalsContact CG1-CD1 3.44Å
580K85.1Confident86.9Confident85 Ų8566 Ų6637%0.3736%0.355SS..Hα-helixtrans-57.4-34.7174.1-71.9178.2177.6173.30111.7M575 S576 P577 Y582 F583 L590M575-K580 VanDerWaalsContact O-CE 3.29Å; M575-K580 WeakPolarHBondContact O-CE 3.32Å; M575-K580 PolarHBondContact O-NZ 3.49Å; S576-K580 PolarHBondContact O-N 2.97Å; S576-K580 VanDerWaalsContact O-N 3.14Å; P577-K580 PolarHBondContact O-N 2.84Å; K580-Y582 VanDerWaalsContact C-N 3.27Å; K580-Y582 PolarHBondContact O-N 2.81Å; K580-F583 CarbonylContact O-C 3.36Å; K580-F583 PolarHBondContact O-N 3.07Å; K580-F583 VanDerWaalsContact O-N 3.13Å; K580-L590 HydrophobicContact CG-CD2 3.84Å
581A86.3Confident86.9Confident73 Ų7370.4 Ų70.460%0.60338%0.376SS*.Hα-helixtrans-64.8-25.3176.800000114.1P577 Q578 V579 F583P577-A581 PolarHBondContact O-N 2.92Å; Q578-A581 WeakPolarHBondContact O-CB 3.35Å; Q578-A581 PolarHBondContact O-N 2.78Å; V579-A581 PolarHBondContact O-N 2.69Å; A581-F583 VanDerWaalsContact C-N 3.33Å
582Y85.3Confident87Confident150 Ų15074.8 Ų74.859%0.58840%0.395SS*.Hα-helixtrans-75.4-21.1174.2-75-80.6000113.3Y237 Q578 V579 K580 P584Y237-Y582 AromaticContact CD1-CE2 3.95Å; Y237-Y582 HydrophobicContact CD1-CE2 3.95Å; Y237-Y582 HydrophobicContact CE1-CE2 4.42Å; Y237-Y582 HydrophobicContact CG-CE2 4.36Å; Q578-Y582 WeakPolarHBondContact O-CD2 3.49Å; V579-Y582 WeakPolarHBondContact O-CB 3.27Å; V579-Y582 PolarHBondContact O-N 3.38Å; K580-Y582 VanDerWaalsContact C-N 3.27Å; K580-Y582 PolarHBondContact O-N 2.81Å; Y582-P584 WeakPolarHBondContact O-CD 3.47Å
583F87.9Confident87.1Confident57 Ų5781.6 Ų81.625%0.2542%0.42CS..  trans-125.260.5-178.9-62.2-85.4000111.8K580 A581 E585 Q589 L590 W593K580-F583 CarbonylContact O-C 3.36Å; K580-F583 PolarHBondContact O-N 3.07Å; K580-F583 VanDerWaalsContact O-N 3.13Å; A581-F583 VanDerWaalsContact C-N 3.33Å; F583-E585 VanDerWaalsContact C-N 3.27Å; F583-E585 PolarHBondContact O-N 3.1Å; F583-Q589 HydrophobicContact CD1-CB 4.17Å; F583-L590 HydrophobicContact CB-CB 4.08Å; F583-L590 HydrophobicContact CD2-CB 4.27Å; F583-L590 HydrophobicContact CD2-CD1 3.92Å; F583-L590 HydrophobicContact CE2-CD1 4.36Å; F583-L590 HydrophobicContact CG-CB 4.2Å; F583-W593 AromaticContact CE1-CD1 3.54Å; F583-W593 HydrophobicContact CE1-CG 4.46Å; F583-W593 AromaticContact CE1-NE1 3.97Å; F583-W593 HydrophobicContact CZ-CB 4.42Å; F583-W593 AromaticContact CZ-CD1 3.57Å; F583-W593 HydrophobicContact CZ-CG 4.09Å
584P83.1Confident87.3Confident107 Ų10781.8 Ų81.870%0.69542%0.423SS*.THydrogen-bonded Turntrans-68.7-24-172.227.9-34.5000113.7Y582Y582-P584 WeakPolarHBondContact O-CD 3.47Å
585E84.8Confident87.6Confident194 Ų19484.5 Ų84.591%0.90744%0.437SS*.THydrogen-bonded Turntrans-95.6-20.1-172.8-62.2-169.7172.600114.3F583F583-E585 VanDerWaalsContact C-N 3.27Å; F583-E585 PolarHBondContact O-N 3.1Å
586S89.9Confident88Confident34 Ų3485.3 Ų85.324%0.23845%0.45CS..  trans-150.799.5-169.8-164.60000113.4T588 Q589 L590S586-T588 PolarHBondContact O-N 2.96Å; S586-T588 PolarHBondContact OG-OG1 2.98Å; S586-Q589 PolarHBondContact O-N 2.88Å; S586-Q589 VanDerWaalsContact O-N 3.14Å; S586-L590 PolarHBondContact O-N 2.93Å
587E87.3Confident88.3Confident157 Ų15788.6 Ų88.673%0.73447%0.465SS*.Hα-helixtrans-61.1-30.6174.1-63.5-172.3162.800112.8Q589 L590 I591E587-Q589 VanDerWaalsContact C-N 3.31Å; E587-Q589 PolarHBondContact O-N 3.25Å; E587-L590 WeakPolarHBondContact O-CB 3.46Å; E587-L590 PolarHBondContact O-N 3.27Å; E587-I591 WeakPolarHBondContact O-CG1 3.4Å; E587-I591 PolarHBondContact O-N 3.48Å
588T89.9Confident88.9Confident92 Ų9284.7 Ų84.756%0.56444%0.438SS*.Hα-helixtrans-63.7-36.2176.854.20000112.5S586 L592S586-T588 PolarHBondContact O-N 2.96Å; S586-T588 PolarHBondContact OG-OG1 2.98Å; T588-L592 WeakPolarHBondContact O-CB 3.49Å; T588-L592 VanDerWaalsContact O-CG 3.25Å; T588-L592 WeakPolarHBondContact O-CG 3.32Å; T588-L592 PolarHBondContact O-N 3.45Å
589Q90.6Very high89.5Confident104 Ų10487 Ų8749%0.48645%0.449SS..Hα-helixtrans-70.4-40.2177.2-71.6-177-4.600110.8F583 S586 E587 L592 W593F583-Q589 HydrophobicContact CD1-CB 4.17Å; S586-Q589 PolarHBondContact O-N 2.88Å; S586-Q589 VanDerWaalsContact O-N 3.14Å; E587-Q589 VanDerWaalsContact C-N 3.31Å; E587-Q589 PolarHBondContact O-N 3.25Å; Q589-L592 PolarHBondContact O-N 2.7Å; Q589-W593 VanDerWaalsContact O-CD1 3.23Å; Q589-W593 PolarHBondContact O-N 3.06Å
590L90.3Very high90Very high15 Ų1588.7 Ų88.78%0.07947%0.467CS..Hα-helixtrans-56.3-52.3173.217159.7000111V579 K580 F583 S586 E587 L592 W593 T594V579-L590 HydrophobicContact CG1-CD1 3.44Å; V579-L590 VanDerWaalsContact CG1-CD1 3.44Å; K580-L590 HydrophobicContact CG-CD2 3.84Å; F583-L590 HydrophobicContact CB-CB 4.08Å; F583-L590 HydrophobicContact CD2-CB 4.27Å; F583-L590 HydrophobicContact CD2-CD1 3.92Å; F583-L590 HydrophobicContact CE2-CD1 4.36Å; F583-L590 HydrophobicContact CG-CB 4.2Å; S586-L590 PolarHBondContact O-N 2.93Å; E587-L590 WeakPolarHBondContact O-CB 3.46Å; E587-L590 PolarHBondContact O-N 3.27Å; L590-L592 VanDerWaalsContact C-N 3.34Å; L590-L592 PolarHBondContact O-N 3.12Å; L590-W593 PolarHBondContact O-N 2.95Å; L590-T594 PolarHBondContact O-N 3.44Å; L590-T594 PolarHBondContact O-OG1 3.31Å; L590-T594 VanDerWaalsContact O-OG1 3.06Å
591I91.5Very high90.3Very high104 Ų10486 Ų8653%0.53346%0.457SS..Hα-helixtrans-59.7-45179.6-65.8166.6000110.9E587 W593 T594 V595E587-I591 WeakPolarHBondContact O-CG1 3.4Å; E587-I591 PolarHBondContact O-N 3.48Å; I591-W593 PolarHBondContact O-N 3.24Å; I591-T594 PolarHBondContact O-N 3.06Å; I591-V595 HydrophobicContact CG2-CG2 4.28Å; I591-V595 WeakPolarHBondContact O-CB 3.26Å; I591-V595 VanDerWaalsContact O-CG2 3.29Å; I591-V595 WeakPolarHBondContact O-CG2 3.34Å; I591-V595 PolarHBondContact O-N 3.06Å
592L92.7Very high90.7Very high122 Ų12283.9 Ų83.964%0.63944%0.435SS*.Hα-helixtrans-61.7-42179-74171.9000112.2T588 Q589 L590 A596T588-L592 WeakPolarHBondContact O-CB 3.49Å; T588-L592 VanDerWaalsContact O-CG 3.25Å; T588-L592 WeakPolarHBondContact O-CG 3.32Å; T588-L592 PolarHBondContact O-N 3.45Å; Q589-L592 PolarHBondContact O-N 2.7Å; L590-L592 VanDerWaalsContact C-N 3.34Å; L590-L592 PolarHBondContact O-N 3.12Å; L592-A596 VanDerWaalsContact O-CB 3.28Å; L592-A596 WeakPolarHBondContact O-CB 3.46Å; L592-A596 PolarHBondContact O-N 3.29Å
593W90.9Very high91.2Very high151 Ų15179 Ų7957%0.57243%0.426SS*.Hα-helixtrans-67.3-42.7175.8-83.7114000112.4F583 Q589 L590 I591 V595 A596 I597F583-W593 AromaticContact CE1-CD1 3.54Å; F583-W593 HydrophobicContact CE1-CG 4.46Å; F583-W593 AromaticContact CE1-NE1 3.97Å; F583-W593 HydrophobicContact CZ-CB 4.42Å; F583-W593 AromaticContact CZ-CD1 3.57Å; F583-W593 HydrophobicContact CZ-CG 4.09Å; Q589-W593 VanDerWaalsContact O-CD1 3.23Å; Q589-W593 PolarHBondContact O-N 3.06Å; L590-W593 PolarHBondContact O-N 2.95Å; I591-W593 PolarHBondContact O-N 3.24Å; W593-V595 PolarHBondContact O-N 3.45Å; W593-A596 PolarHBondContact O-N 3.48Å; W593-I597 VanDerWaalsContact O-CG1 3.32Å; W593-I597 WeakPolarHBondContact O-CG1 3.29Å; W593-I597 PolarHBondContact O-N 3.4Å
594T91.1Very high91.4Very high29 Ų2981 Ų8118%0.17844%0.435CS..Hα-helixtrans-59.8-45.8175.4-59.50000111.3C570 L590 I591 I597 E598C570-T594 HydrophobicContact CB-CG2 4.36Å; C570-T594 WeakPolarHBondContact O-CG2 3.29Å; L590-T594 PolarHBondContact O-N 3.44Å; L590-T594 PolarHBondContact O-OG1 3.31Å; L590-T594 VanDerWaalsContact O-OG1 3.06Å; I591-T594 PolarHBondContact O-N 3.06Å; T594-I597 PolarHBondContact O-N 3.14Å; T594-E598 VanDerWaalsContact O-CB 3.29Å; T594-E598 WeakPolarHBondContact O-CB 3.33Å; T594-E598 PolarHBondContact O-N 3.35Å
595V94.3Very high91.9Very high65 Ų6576.3 Ų76.339%0.39440%0.403SS..Hα-helixtrans-65.7-39.9176.9172.80000111.4I591 W593 E598 H599I591-V595 HydrophobicContact CG2-CG2 4.28Å; I591-V595 WeakPolarHBondContact O-CB 3.26Å; I591-V595 VanDerWaalsContact O-CG2 3.29Å; I591-V595 WeakPolarHBondContact O-CG2 3.34Å; I591-V595 PolarHBondContact O-N 3.06Å; W593-V595 PolarHBondContact O-N 3.45Å; V595-E598 PolarHBondContact O-N 2.93Å; V595-H599 PolarHBondContact O-N 3.41Å; V595-H599 PolarHBondContact O-ND1 3.38Å
596A94Very high92.3Very high56 Ų5672.6 Ų72.646%0.46338%0.384SS..Hα-helixtrans-63.4-42176.800000112.4L592 W593 G600L592-A596 VanDerWaalsContact O-CB 3.28Å; L592-A596 WeakPolarHBondContact O-CB 3.46Å; L592-A596 PolarHBondContact O-N 3.29Å; W593-A596 PolarHBondContact O-N 3.48Å; A596-G600 PolarHBondContact O-N 3.39Å
597I91.3Very high92.5Very high87 Ų8775.3 Ų75.345%0.44640%0.395SS..Hα-helixtrans-64.4-44174.8-69.3167.2000110.3W593 T594 G600 L601W593-I597 VanDerWaalsContact O-CG1 3.32Å; W593-I597 WeakPolarHBondContact O-CG1 3.29Å; W593-I597 PolarHBondContact O-N 3.4Å; T594-I597 PolarHBondContact O-N 3.14Å; I597-G600 PolarHBondContact O-N 3.42Å; I597-L601 HydrophobicContact CG2-CD1 4.08Å; I597-L601 HydrophobicContact CG2-CG 4.4Å; I597-L601 WeakPolarHBondContact O-CG 3.49Å; I597-L601 PolarHBondContact O-N 3.06Å
598E94.1Very high92.8Very high24 Ų2469.1 Ų69.111%0.11237%0.367CS..Hα-helixtrans-59.3-49.5178177.4-8414900111.7V567 C570 T594 V595 G600 L601 L602V567-E598 HydrophobicContact CG2-CG 4.44Å; C570-E598 HydrophobicContact CB-CB 3.94Å; C570-E598 HydrophobicContact CB-CG 4.26Å; T594-E598 VanDerWaalsContact O-CB 3.29Å; T594-E598 WeakPolarHBondContact O-CB 3.33Å; T594-E598 PolarHBondContact O-N 3.35Å; V595-E598 PolarHBondContact O-N 2.93Å; E598-G600 VanDerWaalsContact C-N 3.29Å; E598-G600 PolarHBondContact O-N 3.21Å; E598-L601 PolarHBondContact O-N 2.71Å; E598-L602 PolarHBondContact O-N 3.23Å; E598-L602 WeakPolarHBondContact OE1-CD1 3.49Å; E598-L602 WeakPolarHBondContact OE1-CG 3.37Å
599H95Very high92.9Very high115 Ų11566.9 Ų66.953%0.53235%0.353SS..Hα-helixtrans-62-37174.5-77.763.5000112.2V595 L602 A603V595-H599 PolarHBondContact O-N 3.41Å; V595-H599 PolarHBondContact O-ND1 3.38Å; H599-L602 PolarHBondContact O-N 2.88Å; H599-A603 VanDerWaalsContact O-CB 3.26Å; H599-A603 WeakPolarHBondContact O-CB 3.15Å; H599-A603 PolarHBondContact O-N 3.03Å
600G94.1Very high92.9Very high42 Ų4270.5 Ų70.543%0.43337%0.368SS..Hα-helixtrans-62.1-44.3174.600000112.6A596 I597 E598 A603 F604A596-G600 PolarHBondContact O-N 3.39Å; I597-G600 PolarHBondContact O-N 3.42Å; E598-G600 VanDerWaalsContact C-N 3.29Å; E598-G600 PolarHBondContact O-N 3.21Å; G600-A603 PolarHBondContact O-N 3.42Å; G600-F604 WeakPolarHBondContact O-CB 3.11Å; G600-F604 PolarHBondContact O-N 2.94Å
601L92.6Very high93.1Very high28 Ų2875.2 Ų75.215%0.14739%0.393CS..Hα-helixtrans-69-40.1176.8-71.5175.8000112.2V245 V566 I597 E598 F604 K605V245-L601 HydrophobicContact CG2-CD2 4.26Å; V566-L601 HydrophobicContact CG1-CB 3.9Å; I597-L601 HydrophobicContact CG2-CD1 4.08Å; I597-L601 HydrophobicContact CG2-CG 4.4Å; I597-L601 WeakPolarHBondContact O-CG 3.49Å; I597-L601 PolarHBondContact O-N 3.06Å; E598-L601 PolarHBondContact O-N 2.71Å; L601-F604 PolarHBondContact O-N 2.93Å; L601-K605 WeakPolarHBondContact O-CB 3.36Å; L601-K605 PolarHBondContact O-N 3.09Å
602L94.7Very high93.2Very high28 Ų2872 Ų7215%0.14738%0.376CS..Hα-helixtrans-62.6-46172.9-76.2-170.6000111.7V563 V566 E598 H599 F604 K605 F606V563-L602 HydrophobicContact CG1-CD2 4.04Å; V566-L602 HydrophobicContact CB-CD2 3.87Å; V566-L602 HydrophobicContact CG1-CD2 3.85Å; V566-L602 HydrophobicContact CG1-CG 4.07Å; V566-L602 HydrophobicContact CG2-CD2 4.07Å; E598-L602 PolarHBondContact O-N 3.23Å; E598-L602 WeakPolarHBondContact OE1-CD1 3.49Å; E598-L602 WeakPolarHBondContact OE1-CG 3.37Å; H599-L602 PolarHBondContact O-N 2.88Å; L602-F604 VanDerWaalsContact C-N 3.32Å; L602-F604 PolarHBondContact O-N 3.29Å; L602-K605 WeakPolarHBondContact O-CB 3.29Å; L602-K605 PolarHBondContact O-N 2.98Å; L602-F606 HydrophobicContact CB-CE2 4.31Å; L602-F606 WeakPolarHBondContact O-CD2 3.3Å; L602-F606 PolarHBondContact O-N 3.31Å
603A94.8Very high93.2Very high49 Ų4969.1 Ų69.141%0.40537%0.365SS..Hα-helixtrans-59.1-45.9176.100000110.9H599 G600 K605 F606 I607H599-A603 VanDerWaalsContact O-CB 3.26Å; H599-A603 WeakPolarHBondContact O-CB 3.15Å; H599-A603 PolarHBondContact O-N 3.03Å; G600-A603 PolarHBondContact O-N 3.42Å; A603-K605 PolarHBondContact O-N 3.46Å; A603-F606 PolarHBondContact O-N 3.15Å; A603-I607 WeakPolarHBondContact O-CB 3.46Å; A603-I607 WeakPolarHBondContact O-CD1 3.3Å; A603-I607 WeakPolarHBondContact O-CG1 3.33Å; A603-I607 PolarHBondContact O-N 2.98Å
604F92.7Very high93.3Very high97 Ų9765.7 Ų65.743%0.42536%0.358SS..Hα-helixtrans-60.1-43.7175.7-176.1-107.7000112.4V249 G600 L601 L602 I607 L608V249-F604 HydrophobicContact CG1-CE1 4.38Å; V249-F604 HydrophobicContact CG2-CD1 4.06Å; V249-F604 HydrophobicContact CG2-CE1 3.59Å; G600-F604 WeakPolarHBondContact O-CB 3.11Å; G600-F604 PolarHBondContact O-N 2.94Å; L601-F604 PolarHBondContact O-N 2.93Å; L602-F604 VanDerWaalsContact C-N 3.32Å; L602-F604 PolarHBondContact O-N 3.29Å; F604-I607 PolarHBondContact O-N 2.79Å; F604-L608 HydrophobicContact CD1-CD1 3.9Å; F604-L608 HydrophobicContact CD1-CG 4.33Å; F604-L608 HydrophobicContact CE1-CD1 3.36Å; F604-L608 HydrophobicContact CE1-CD2 4.47Å; F604-L608 HydrophobicContact CE1-CG 3.91Å; F604-L608 HydrophobicContact CE2-CG 4.44Å; F604-L608 HydrophobicContact CZ-CD1 3.84Å; F604-L608 HydrophobicContact CZ-CD2 4.1Å; F604-L608 HydrophobicContact CZ-CG 3.97Å; F604-L608 WeakPolarHBondContact O-CG 3.2Å; F604-L608 PolarHBondContact O-N 3.48Å
605K93.1Very high93.4Very high9 Ų966 Ų664%0.03936%0.36CS..Hα-helixtrans-57.7-50.7174.9171.5174.9-176.673.80111.8T252 S562 V563 V566 L601 L602 A603 I607 L608 T609T252-K605 HydrophobicContact CG2-CG 3.91Å; T252-K605 WeakPolarHBondContact OG1-CG 3Å; T252-K605 PolarHBondContact OG1-NZ 3.36Å; S562-K605 PolarHBondContact OG-NZ 3.28Å; V563-K605 HydrophobicContact CG2-CD 4.26Å; V566-K605 HydrophobicContact CG2-CD 4.23Å; L601-K605 WeakPolarHBondContact O-CB 3.36Å; L601-K605 PolarHBondContact O-N 3.09Å; L602-K605 WeakPolarHBondContact O-CB 3.29Å; L602-K605 PolarHBondContact O-N 2.98Å; A603-K605 PolarHBondContact O-N 3.46Å; K605-I607 VanDerWaalsContact C-N 3.31Å; K605-I607 PolarHBondContact O-N 3.4Å; K605-L608 WeakPolarHBondContact O-CB 3.15Å; K605-L608 PolarHBondContact O-N 2.87Å; K605-T609 PolarHBondContact O-N 2.8Å
606F93.9Very high93.5Very high116 Ų11663.4 Ų63.451%0.50934%0.344SS..Hα-helixtrans-65.4-34.7179.1-71.2-59.7000112.5V563 L602 A603 T609 F610V563-F606 HydrophobicContact CG2-CZ 4.48Å; L602-F606 HydrophobicContact CB-CE2 4.31Å; L602-F606 WeakPolarHBondContact O-CD2 3.3Å; L602-F606 PolarHBondContact O-N 3.31Å; A603-F606 PolarHBondContact O-N 3.15Å; F606-T609 PolarHBondContact O-N 2.92Å; F606-F610 WeakPolarHBondContact O-CB 3.43Å; F606-F610 PolarHBondContact O-N 3.23Å
607I94.6Very high93.5Very high91 Ų9168.3 Ų68.347%0.46736%0.355SS..Hα-helixtrans-62.3-46.2171.9-70.2164.2000110.4A603 F604 K605 T609 F610 L611A603-I607 WeakPolarHBondContact O-CB 3.46Å; A603-I607 WeakPolarHBondContact O-CD1 3.3Å; A603-I607 WeakPolarHBondContact O-CG1 3.33Å; A603-I607 PolarHBondContact O-N 2.98Å; F604-I607 PolarHBondContact O-N 2.79Å; K605-I607 VanDerWaalsContact C-N 3.31Å; K605-I607 PolarHBondContact O-N 3.4Å; I607-T609 PolarHBondContact O-N 3.39Å; I607-F610 PolarHBondContact O-N 3.03Å; I607-F610 VanDerWaalsContact O-N 3.15Å; I607-L611 HydrophobicContact CG2-CD1 3.71Å; I607-L611 HydrophobicContact CG2-CG 4.13Å; I607-L611 WeakPolarHBondContact O-CB 3.49Å; I607-L611 VanDerWaalsContact O-CG 3.25Å; I607-L611 WeakPolarHBondContact O-CG 3.48Å; I607-L611 PolarHBondContact O-N 3.27Å
608L92.3Very high93.7Very high27 Ų2769.2 Ų69.214%0.14136%0.357CS..Hα-helixtrans-60-45.6177-76.8179.4000112.3V249 T252 F604 K605 F610 L611 I612V249-L608 HydrophobicContact CG1-CD1 4.15Å; T252-L608 HydrophobicContact CG2-CB 4.08Å; T252-L608 HydrophobicContact CG2-CD1 4.48Å; F604-L608 HydrophobicContact CD1-CD1 3.9Å; F604-L608 HydrophobicContact CD1-CG 4.33Å; F604-L608 HydrophobicContact CE1-CD1 3.36Å; F604-L608 HydrophobicContact CE1-CD2 4.47Å; F604-L608 HydrophobicContact CE1-CG 3.91Å; F604-L608 HydrophobicContact CE2-CG 4.44Å; F604-L608 HydrophobicContact CZ-CD1 3.84Å; F604-L608 HydrophobicContact CZ-CD2 4.1Å; F604-L608 HydrophobicContact CZ-CG 3.97Å; F604-L608 WeakPolarHBondContact O-CG 3.2Å; F604-L608 PolarHBondContact O-N 3.48Å; K605-L608 WeakPolarHBondContact O-CB 3.15Å; K605-L608 PolarHBondContact O-N 2.87Å; L608-F610 VanDerWaalsContact C-N 3.26Å; L608-F610 PolarHBondContact O-N 3.26Å; L608-L611 PolarHBondContact O-N 2.99Å; L608-L611 VanDerWaalsContact O-N 3.17Å; L608-I612 WeakPolarHBondContact O-CG1 3.25Å; L608-I612 PolarHBondContact O-N 3.5Å
609T91.8Very high93.6Very high45 Ų4568.1 Ų68.128%0.27635%0.352SS..Hα-helixtrans-59.4-37.5174.7-72.80000111.9E256 K605 F606 I607E256-T609 VanDerWaalsContact OE1-CB 3.3Å; E256-T609 WeakPolarHBondContact OE1-CB 3.39Å; E256-T609 WeakPolarHBondContact OE1-CG2 3.35Å; E256-T609 PolarHBondContact OE1-OG1 3.27Å; K605-T609 PolarHBondContact O-N 2.8Å; F606-T609 PolarHBondContact O-N 2.92Å; I607-T609 PolarHBondContact O-N 3.39Å
610F91.9Very high93.6Very high180 Ų18066.8 Ų66.879%0.78935%0.346SS*.Hα-helixtrans-72-35175.6-178.2-99.8000113.2F606 I607 L608F606-F610 WeakPolarHBondContact O-CB 3.43Å; F606-F610 PolarHBondContact O-N 3.23Å; I607-F610 PolarHBondContact O-N 3.03Å; I607-F610 VanDerWaalsContact O-N 3.15Å; L608-F610 VanDerWaalsContact C-N 3.26Å; L608-F610 PolarHBondContact O-N 3.26Å
611L93.8Very high93.6Very high115 Ų11569.4 Ų69.460%0.60235%0.349SS*.Hα-helixtrans-74.3-30.5-177.9-73.8174.3000113.3I607 L608 P613I607-L611 HydrophobicContact CG2-CD1 3.71Å; I607-L611 HydrophobicContact CG2-CG 4.13Å; I607-L611 WeakPolarHBondContact O-CB 3.49Å; I607-L611 VanDerWaalsContact O-CG 3.25Å; I607-L611 WeakPolarHBondContact O-CG 3.48Å; I607-L611 PolarHBondContact O-N 3.27Å; L608-L611 PolarHBondContact O-N 2.99Å; L608-L611 VanDerWaalsContact O-N 3.17Å; L611-P613 VanDerWaalsContact O-CD 3.29Å; L611-P613 WeakPolarHBondContact O-CD 3.37Å
612I92.9Very high93.6Very high35 Ų3572.4 Ų72.418%0.17936%0.361CS..SBendtrans-93.9107.3-179.1-59.1170.4000108.4E256 L608 D614E256-I612 HydrophobicContact CB-CB 4.11Å; E256-I612 HydrophobicContact CB-CD1 3.97Å; E256-I612 HydrophobicContact CB-CG2 3.84Å; E256-I612 HydrophobicContact CG-CB 4.42Å; E256-I612 HydrophobicContact CG-CD1 4.28Å; L608-I612 WeakPolarHBondContact O-CG1 3.25Å; L608-I612 PolarHBondContact O-N 3.5Å; I612-D614 PolarHBondContact O-N 3.12Å
613P93Very high93.5Very high62 Ų6273.4 Ų73.440%0.40337%0.366SS..  trans-72.9133.6-178.125.3-28.5000110.8R260 L611 V615R260-P613 WeakPolarHBondContact CD-O 3.33Å; R260-P613 WeakPolarHBondContact CG-O 3.29Å; R260-P613 PolarHBondContact NH1-O 3.04Å; L611-P613 VanDerWaalsContact O-CD 3.29Å; L611-P613 WeakPolarHBondContact O-CD 3.37Å; P613-V615 VanDerWaalsContact C-N 3.26Å; P613-V615 PolarHBondContact O-N 3.21Å
614D93.4Very high93.4Very high80 Ų8073.7 Ų73.743%0.42837%0.368SS..SBendtrans-54.4-38.1-179.5-66-16.2000113.5K259 R260 I612K259-D614 CarbonylContact C-O 3.6Å; K259-D614 HydrophobicContact CB-CB 4.42Å; K259-D614 WeakPolarHBondContact CD-OD1 3.48Å; K259-D614 WeakPolarHBondContact CE-OD1 3.27Å; K259-D614 IonicContact NZ-OD1 2.93Å; K259-D614 PolarHBondContact NZ-OD1 3.09Å; R260-D614 WeakPolarHBondContact CA-O 3.49Å; R260-D614 WeakPolarHBondContact CG-O 3.45Å; R260-D614 PolarHBondContact N-O 3.5Å; I612-D614 PolarHBondContact O-N 3.12Å
615V94.1Very high93.4Very high35 Ų3577.2 Ų77.221%0.21238%0.379CS..SBendtrans-109.1129.6-179.2-176.80000109.7A263 P613 I619 Q620A263-V615 HydrophobicContact CB-CG1 4.43Å; A263-V615 HydrophobicContact CB-CG2 4.17Å; P613-V615 VanDerWaalsContact C-N 3.26Å; P613-V615 PolarHBondContact O-N 3.21Å; V615-I619 HydrophobicContact CG1-CB 3.78Å; V615-I619 HydrophobicContact CG1-CG2 3.69Å; V615-Q620 HydrophobicContact CB-CG 3.94Å; V615-Q620 HydrophobicContact CG1-CG 3.8Å; V615-Q620 PolarHBondContact O-NE2 3.46Å
616P95.5Very high93.3Very high10 Ų1079.1 Ų79.17%0.06539%0.389CS..  trans-58.3143.8175-26.334.7000113.6R260 H618 I619 Q620R260-P616 HydrophobicContact CB-CG 4.32Å; P616-H618 VanDerWaalsContact C-N 3.29Å; P616-H618 PolarHBondContact O-N 3.01Å; P616-H618 VanDerWaalsContact O-N 3.16Å; P616-I619 HydrophobicContact CB-CD1 4.45Å; P616-I619 HydrophobicContact CB-CG1 4.43Å; P616-I619 HydrophobicContact CG-CD1 4.2Å; P616-I619 PolarHBondContact O-N 2.95Å; P616-Q620 PolarHBondContact O-N 2.99Å
617K94.8Very high93.2Very high159 Ų15979.9 Ų79.969%0.69139%0.394SS*.Hα-helixtrans-53.5-40.3-175.9-173.6174.8-177.9176.70114I619 Q620 I621K617-I619 VanDerWaalsContact C-N 3.31Å; K617-I619 PolarHBondContact O-N 3.49Å; K617-Q620 PolarHBondContact O-N 2.94Å; K617-I621 HydrophobicContact CG-CD1 4.19Å; K617-I621 VanDerWaalsContact O-CG1 3.31Å; K617-I621 WeakPolarHBondContact O-CG1 3.46Å; K617-I621 PolarHBondContact O-N 2.9Å
618H93.8Very high93.1Very high106 Ų10681.7 Ų81.749%0.49140%0.399SS..Hα-helixtrans-66-33.5179.871.3-84.4000112.4P616 K622P616-H618 VanDerWaalsContact C-N 3.29Å; P616-H618 PolarHBondContact O-N 3.01Å; P616-H618 VanDerWaalsContact O-N 3.16Å; H618-K622 WeakPolarHBondContact O-CG 3.2Å; H618-K622 PolarHBondContact O-N 3.18Å
619I93.9Very high93.1Very high1 Ų183.1 Ų83.11%0.00541%0.405CS..Hα-helixtrans-74.9-42175.5-58.9-177.5000110.2T264 Y267 L272 V615 P616 K617 I621 K622 L623T264-I619 VanDerWaalsContact CA-CD1 3.44Å; T264-I619 HydrophobicContact CG2-CD1 4.22Å; Y267-I619 HydrophobicContact CD2-CG2 3.73Å; Y267-I619 HydrophobicContact CG-CD1 4.45Å; Y267-I619 HydrophobicContact CG-CG1 4.47Å; Y267-I619 HydrophobicContact CG-CG2 3.85Å; L272-I619 HydrophobicContact CD2-CG2 3.98Å; V615-I619 HydrophobicContact CG1-CB 3.78Å; V615-I619 HydrophobicContact CG1-CG2 3.69Å; P616-I619 HydrophobicContact CB-CD1 4.45Å; P616-I619 HydrophobicContact CB-CG1 4.43Å; P616-I619 HydrophobicContact CG-CD1 4.2Å; P616-I619 PolarHBondContact O-N 2.95Å; K617-I619 VanDerWaalsContact C-N 3.31Å; K617-I619 PolarHBondContact O-N 3.49Å; I619-I621 VanDerWaalsContact C-N 3.26Å; I619-I621 PolarHBondContact O-N 2.97Å; I619-K622 PolarHBondContact O-N 3.28Å; I619-L623 HydrophobicContact CG2-CD1 4.06Å; I619-L623 HydrophobicContact CG2-CG 4.21Å; I619-L623 WeakPolarHBondContact O-CG 3.47Å; I619-L623 PolarHBondContact O-N 3.31Å
620Q94Very high93Very high87 Ų8784.7 Ų84.741%0.40742%0.418SS..Hα-helixtrans-54.4-44174.2-65.2-179500111.5V615 P616 K617 K622 L623 A624V615-Q620 HydrophobicContact CB-CG 3.94Å; V615-Q620 HydrophobicContact CG1-CG 3.8Å; V615-Q620 PolarHBondContact O-NE2 3.46Å; P616-Q620 PolarHBondContact O-N 2.99Å; K617-Q620 PolarHBondContact O-N 2.94Å; Q620-K622 PolarHBondContact O-N 3.28Å; Q620-L623 PolarHBondContact O-N 3.03Å; Q620-A624 VanDerWaalsContact O-CB 3.31Å; Q620-A624 WeakPolarHBondContact O-CB 3.5Å; Q620-A624 PolarHBondContact O-N 3.48Å
621I94.4Very high93.1Very high97 Ų9780.4 Ų80.450%0.49740%0.403SS..Hα-helixtrans-62.7-42.8176.5-67.2164.9000111.2K617 I619 A624 R625K617-I621 HydrophobicContact CG-CD1 4.19Å; K617-I621 VanDerWaalsContact O-CG1 3.31Å; K617-I621 WeakPolarHBondContact O-CG1 3.46Å; K617-I621 PolarHBondContact O-N 2.9Å; I619-I621 VanDerWaalsContact C-N 3.26Å; I619-I621 PolarHBondContact O-N 2.97Å; I621-A624 PolarHBondContact O-N 2.96Å; I621-R625 WeakPolarHBondContact O-CB 3.45Å; I621-R625 PolarHBondContact O-N 3.01Å
622K92.8Very high93.1Very high92 Ų9278.5 Ų78.540%0.439%0.391SS..Hα-helixtrans-64.6-42.4178.1-71.1-174.3-176.6-169.60112Y267 H618 I619 Q620 R625 L626Y267-K622 HydrophobicContact CE1-CD 3.68Å; Y267-K622 HydrophobicContact CE2-CB 4.03Å; Y267-K622 HydrophobicContact CE2-CD 4.4Å; Y267-K622 VanDerWaalsContact OH-CD 3.28Å; Y267-K622 WeakPolarHBondContact OH-CD 3.27Å; H618-K622 WeakPolarHBondContact O-CG 3.2Å; H618-K622 PolarHBondContact O-N 3.18Å; I619-K622 PolarHBondContact O-N 3.28Å; Q620-K622 PolarHBondContact O-N 3.28Å; K622-R625 PolarHBondContact O-N 2.77Å; K622-L626 PolarHBondContact O-N 2.95Å
623L91.9Very high93Very high49 Ų4979.6 Ų79.626%0.25741%0.405SS..Hα-helixtrans-64.8-45175.7-67.5175.2000111.8Y267 L272 I619 Q620 R625 L626 E627Y267-L623 HydrophobicContact CD2-CD2 4.24Å; Y267-L623 HydrophobicContact CE2-CD2 4.31Å; L272-L623 HydrophobicContact CD2-CD1 4Å; I619-L623 HydrophobicContact CG2-CD1 4.06Å; I619-L623 HydrophobicContact CG2-CG 4.21Å; I619-L623 WeakPolarHBondContact O-CG 3.47Å; I619-L623 PolarHBondContact O-N 3.31Å; Q620-L623 PolarHBondContact O-N 3.03Å; L623-R625 VanDerWaalsContact C-N 3.31Å; L623-R625 PolarHBondContact O-N 3.31Å; L623-L626 WeakPolarHBondContact O-CB 3.22Å; L623-L626 PolarHBondContact O-N 2.95Å; L623-E627 PolarHBondContact O-N 2.81Å
624A92.9Very high93Very high55 Ų5580.8 Ų80.846%0.45541%0.407SS..Hα-helixtrans-62.7-38176.800000112Q620 I621 E627 F628Q620-A624 VanDerWaalsContact O-CB 3.31Å; Q620-A624 WeakPolarHBondContact O-CB 3.5Å; Q620-A624 PolarHBondContact O-N 3.48Å; I621-A624 PolarHBondContact O-N 2.96Å; A624-E627 PolarHBondContact O-N 3.39Å; A624-F628 WeakPolarHBondContact O-CB 3.35Å; A624-F628 PolarHBondContact O-N 3.13Å
625R92.8Very high93Very high170 Ų17083.7 Ų83.764%0.64242%0.416SS*.Hα-helixtrans-63-45.2173.1178.5177-82.9178.1-6.9111.4I621 K622 L623 E627 F628 E629I621-R625 WeakPolarHBondContact O-CB 3.45Å; I621-R625 PolarHBondContact O-N 3.01Å; K622-R625 PolarHBondContact O-N 2.77Å; L623-R625 VanDerWaalsContact C-N 3.31Å; L623-R625 PolarHBondContact O-N 3.31Å; R625-E627 VanDerWaalsContact C-N 3.32Å; R625-E627 PolarHBondContact O-N 3.32Å; R625-F628 PolarHBondContact O-N 3.33Å; R625-E629 HydrophobicContact CG-CG 4.47Å; R625-E629 WeakPolarHBondContact CG-OE1 3.08Å; R625-E629 WeakPolarHBondContact O-CG 3.07Å; R625-E629 PolarHBondContact O-N 3.03Å
626L90.6Very high93Very high49 Ų4987 Ų8726%0.25743%0.428SS..Hα-helixtrans-60.2-42.2177.5-176.968.2000111.9F86 K622 L623 E629 S630F86-L626 HydrophobicContact CE1-CD2 4.3Å; K622-L626 PolarHBondContact O-N 2.95Å; L623-L626 WeakPolarHBondContact O-CB 3.22Å; L623-L626 PolarHBondContact O-N 2.95Å; L626-E629 PolarHBondContact O-N 3.04Å; L626-S630 PolarHBondContact O-N 3.14Å
627E91.3Very high92.9Very high133 Ų13392.5 Ų92.562%0.62145%0.451SS*.Hα-helixtrans-64.7-44.1175.7-174.3174-164.300112L623 A624 R625 E629 S630 L631L623-E627 PolarHBondContact O-N 2.81Å; A624-E627 PolarHBondContact O-N 3.39Å; R625-E627 VanDerWaalsContact C-N 3.32Å; R625-E627 PolarHBondContact O-N 3.32Å; E627-E629 PolarHBondContact O-N 3.27Å; E627-S630 WeakPolarHBondContact O-CB 3.28Å; E627-S630 PolarHBondContact O-N 3.23Å; E627-L631 HydrophobicContact CG-CD1 4.45Å; E627-L631 WeakPolarHBondContact O-CG 3.3Å; E627-L631 PolarHBondContact O-N 3.42Å
628F93.7Very high92.7Very high129 Ų12991.2 Ų91.257%0.56645%0.445SS*.Hα-helixtrans-59-46.2175.8178.2-95.2000112.1A624 R625 S630 L631 E632A624-F628 WeakPolarHBondContact O-CB 3.35Å; A624-F628 PolarHBondContact O-N 3.13Å; R625-F628 PolarHBondContact O-N 3.33Å; F628-S630 VanDerWaalsContact C-N 3.33Å; F628-S630 PolarHBondContact O-N 3.47Å; F628-L631 PolarHBondContact O-N 2.92Å; F628-E632 PolarHBondContact O-N 3.35Å
629E91.9Very high92.5Very high57 Ų5792.2 Ų92.227%0.26645%0.451SS..Hα-helixtrans-62.4-39.6176.9-72.9179-157.800112R95 R625 L626 E627 E632 A633R95-E629 IonicContact CZ-OE2 2.82Å; R95-E629 IonicContact NH1-OE2 3.53Å; R95-E629 PolarHBondContact NH1-OE2 3.41Å; R95-E629 IonicContact NH2-OE1 3.89Å; R95-E629 IonicContact NH2-OE2 3.77Å; R95-E629 PolarHBondContact NH2-OE2 3.48Å; R625-E629 HydrophobicContact CG-CG 4.47Å; R625-E629 WeakPolarHBondContact CG-OE1 3.08Å; R625-E629 WeakPolarHBondContact O-CG 3.07Å; R625-E629 PolarHBondContact O-N 3.03Å; L626-E629 PolarHBondContact O-N 3.04Å; E627-E629 PolarHBondContact O-N 3.27Å; E629-E632 PolarHBondContact O-N 3.27Å; E629-A633 WeakPolarHBondContact O-CB 3.32Å; E629-A633 PolarHBondContact O-N 3.25Å
630S90.8Very high92.3Very high78 Ų7897.6 Ų97.655%0.54548%0.48SS..Hα-helixtrans-62-43.1175-176.30000112L626 E627 F628 A633 L634L626-S630 PolarHBondContact O-N 3.14Å; E627-S630 WeakPolarHBondContact O-CB 3.28Å; E627-S630 PolarHBondContact O-N 3.23Å; F628-S630 VanDerWaalsContact C-N 3.33Å; F628-S630 PolarHBondContact O-N 3.47Å; S630-A633 PolarHBondContact O-N 3.01Å; S630-L634 PolarHBondContact O-N 3.41Å
631L93.2Very high92Very high89 Ų8998 Ų9847%0.46648%0.482SS..Hα-helixtrans-65.6-40.3175.9-71.6171.2000112E627 F628 L634 K635E627-L631 HydrophobicContact CG-CD1 4.45Å; E627-L631 WeakPolarHBondContact O-CG 3.3Å; E627-L631 PolarHBondContact O-N 3.42Å; F628-L631 PolarHBondContact O-N 2.92Å; L631-L634 PolarHBondContact O-N 3.37Å; L631-K635 WeakPolarHBondContact O-CG 3.41Å; L631-K635 PolarHBondContact O-N 2.98Å
632E93.7Very high91.6Very high76 Ų7694.9 Ų94.936%0.35547%0.474SS..Hα-helixtrans-65.6-42.4177.3-163.1-170.9161.100111.7F628 E629 L634 K635 K636F628-E632 PolarHBondContact O-N 3.35Å; E629-E632 PolarHBondContact O-N 3.27Å; E632-L634 VanDerWaalsContact C-N 3.34Å; E632-L634 PolarHBondContact O-N 3.32Å; E632-K635 PolarHBondContact O-N 3.21Å; E632-K636 WeakPolarHBondContact O-CG 3.37Å; E632-K636 PolarHBondContact O-N 3.21Å; E632-K636 WeakPolarHBondContact OE1-CE 3.47Å; E632-K636 IonicContact OE1-NZ 3.08Å; E632-K636 PolarHBondContact OE1-NZ 2.95Å
633A91.6Very high91.2Very high57 Ų5793.9 Ų93.947%0.47148%0.475SS..Hα-helixtrans-60-44174.600000111.6E629 S630 K635 K636 K637E629-A633 WeakPolarHBondContact O-CB 3.32Å; E629-A633 PolarHBondContact O-N 3.25Å; S630-A633 PolarHBondContact O-N 3.01Å; A633-K635 PolarHBondContact O-N 3.07Å; A633-K636 PolarHBondContact O-N 3.09Å; A633-K637 WeakPolarHBondContact O-CB 3.35Å; A633-K637 PolarHBondContact O-N 3.46Å
634L92.9Very high90.7Very high88 Ų8898 Ų9846%0.46149%0.493SS..Hα-helixtrans-62.7-41.2175.7-177.263.4000112.1S630 L631 E632 K637 K638S630-L634 PolarHBondContact O-N 3.41Å; L631-L634 PolarHBondContact O-N 3.37Å; E632-L634 VanDerWaalsContact C-N 3.34Å; E632-L634 PolarHBondContact O-N 3.32Å; L634-K637 PolarHBondContact O-N 2.89Å; L634-K638 WeakPolarHBondContact O-CG 3.42Å; L634-K638 PolarHBondContact O-N 3.26Å
635K92.9Very high90Very high141 Ų141102 Ų10261%0.61350%0.501SS*.Hα-helixtrans-61.7-47.4175.3-73.9177-172.5179.40111.3L631 E632 A633 K637 K638 M639L631-K635 WeakPolarHBondContact O-CG 3.41Å; L631-K635 PolarHBondContact O-N 2.98Å; E632-K635 PolarHBondContact O-N 3.21Å; A633-K635 PolarHBondContact O-N 3.07Å; K635-K637 PolarHBondContact O-N 3.4Å; K635-K638 PolarHBondContact O-N 3.41Å; K635-M639 WeakPolarHBondContact O-CG 3.31Å; K635-M639 PolarHBondContact O-N 3.16Å
636K93.4Very high89.2Confident104 Ų104103 Ų10345%0.45250%0.504SS..Hα-helixtrans-59.2-46.1177.6-74175.4-176.7165.30111.6E632 A633 K638 M639 L640E632-K636 WeakPolarHBondContact O-CG 3.37Å; E632-K636 PolarHBondContact O-N 3.21Å; E632-K636 WeakPolarHBondContact OE1-CE 3.47Å; E632-K636 IonicContact OE1-NZ 3.08Å; E632-K636 PolarHBondContact OE1-NZ 2.95Å; A633-K636 PolarHBondContact O-N 3.09Å; K636-K638 PolarHBondContact O-N 3.32Å; K636-M639 HydrophobicContact CG-CE 4.33Å; K636-M639 PolarHBondContact O-N 3.3Å; K636-L640 WeakPolarHBondContact O-CG 3.49Å; K636-L640 PolarHBondContact O-N 2.88Å
637K92.9Very high88.5Confident125 Ų125107.8 Ų107.854%0.54352%0.523SS..Hα-helixtrans-56.7-50.1175.4-179.6172.6174.1175.70111.9A633 L634 K635 M639 L640 E641A633-K637 WeakPolarHBondContact O-CB 3.35Å; A633-K637 PolarHBondContact O-N 3.46Å; L634-K637 PolarHBondContact O-N 2.89Å; K635-K637 PolarHBondContact O-N 3.4Å; K637-M639 VanDerWaalsContact C-N 3.33Å; K637-M639 PolarHBondContact O-N 2.85Å; K637-L640 PolarHBondContact O-N 3.06Å; K637-E641 WeakPolarHBondContact CE-OE1 3.34Å; K637-E641 HydrophobicContact CG-CG 4.47Å; K637-E641 IonicContact NZ-OE1 2.67Å; K637-E641 WeakPolarHBondContact O-CG 3.24Å; K637-E641 PolarHBondContact O-N 3.1Å
638K91.1Very high87.7Confident133 Ų133105.5 Ų105.558%0.57852%0.522SS*.Hα-helixtrans-62.3-36.6178.3-72.8-175.8177.4-173.30113.4L634 K635 K636 G642L634-K638 WeakPolarHBondContact O-CG 3.42Å; L634-K638 PolarHBondContact O-N 3.26Å; K635-K638 PolarHBondContact O-N 3.41Å; K636-K638 PolarHBondContact O-N 3.32Å; K638-G642 PolarHBondContact O-N 3.18Å
639M89.4Confident86.7Confident126 Ų126104.3 Ų104.362%0.62153%0.525SS*.Hα-helixtrans-66.7-41175.5-70.9-167.9-48.800112.1K635 K636 K637 G642 T643K635-M639 WeakPolarHBondContact O-CG 3.31Å; K635-M639 PolarHBondContact O-N 3.16Å; K636-M639 HydrophobicContact CG-CE 4.33Å; K636-M639 PolarHBondContact O-N 3.3Å; K637-M639 VanDerWaalsContact C-N 3.33Å; K637-M639 PolarHBondContact O-N 2.85Å; M639-G642 PolarHBondContact O-N 3.26Å; M639-T643 WeakPolarHBondContact O-CB 3.48Å; M639-T643 PolarHBondContact O-N 3.16Å; M639-T643 PolarHBondContact O-OG1 3.06Å
640L90.3Very high85.2Confident114 Ų114111.9 Ų111.960%0.59756%0.56SS**Hα-helixtrans-64.5-49.9176.5-70.8168.6000110.8K636 K637 G642 T643 E644K636-L640 WeakPolarHBondContact O-CG 3.49Å; K636-L640 PolarHBondContact O-N 2.88Å; K637-L640 PolarHBondContact O-N 3.06Å; L640-G642 VanDerWaalsContact C-N 3.3Å; L640-G642 PolarHBondContact O-N 3.2Å; L640-T643 CarbonylContact O-C 3.57Å; L640-T643 WeakPolarHBondContact O-CA 3.13Å; L640-T643 WeakPolarHBondContact O-CB 3.35Å; L640-T643 PolarHBondContact O-N 3.17Å; L640-E644 PolarHBondContact O-N 2.73Å
641E88.4Confident85Confident96 Ų96113.6 Ų113.645%0.44956%0.561SS.*Hα-helixtrans-57.3-42.2176.2-71.9170.7172.100111.7K637 T643 E644 F645K637-E641 WeakPolarHBondContact CE-OE1 3.34Å; K637-E641 HydrophobicContact CG-CG 4.47Å; K637-E641 IonicContact NZ-OE1 2.67Å; K637-E641 WeakPolarHBondContact O-CG 3.24Å; K637-E641 PolarHBondContact O-N 3.1Å; E641-T643 VanDerWaalsContact C-N 3.3Å; E641-T643 PolarHBondContact O-N 3.01Å; E641-E644 PolarHBondContact O-N 3.49Å; E641-F645 WeakPolarHBondContact O-CB 3.44Å; E641-F645 PolarHBondContact O-N 3.45Å
642G85.8Confident84.5Confident32 Ų32114.8 Ų114.833%0.3357%0.566SS.*Hα-helixtrans-65.7-31.7175.100000113.5K638 M639 L640 R646K638-G642 PolarHBondContact O-N 3.18Å; M639-G642 PolarHBondContact O-N 3.26Å; L640-G642 VanDerWaalsContact C-N 3.3Å; L640-G642 PolarHBondContact O-N 3.2Å; G642-R646 VanDerWaalsContact O-CG 3.32Å; G642-R646 WeakPolarHBondContact O-CG 3.04Å; G642-R646 PolarHBondContact O-N 2.87Å; G642-R646 VanDerWaalsContact O-N 3.11Å
643T84.1Confident84Confident70 Ų70117 Ų11743%0.42958%0.577SS.*Hα-helixtrans-75.5-41.6176.8-53.40000111.2M639 L640 E641 R646 K647M639-T643 WeakPolarHBondContact O-CB 3.48Å; M639-T643 PolarHBondContact O-N 3.16Å; M639-T643 PolarHBondContact O-OG1 3.06Å; L640-T643 CarbonylContact O-C 3.57Å; L640-T643 WeakPolarHBondContact O-CA 3.13Å; L640-T643 WeakPolarHBondContact O-CB 3.35Å; L640-T643 PolarHBondContact O-N 3.17Å; E641-T643 VanDerWaalsContact C-N 3.3Å; E641-T643 PolarHBondContact O-N 3.01Å; T643-R646 PolarHBondContact O-N 3.31Å; T643-K647 WeakPolarHBondContact O-CG 3.31Å; T643-K647 PolarHBondContact O-N 3.4Å
644E81.3Confident83.6Confident136 Ų136120.5 Ų120.564%0.63658%0.584SS**Hα-helixtrans-63.2-43.2173.2-73.6-175.1167.500111.5L640 E641 R646 K647 S648L640-E644 PolarHBondContact O-N 2.73Å; E641-E644 PolarHBondContact O-N 3.49Å; E644-R646 PolarHBondContact O-N 3.09Å; E644-K647 CarbonylContact O-C 3.59Å; E644-K647 PolarHBondContact O-N 3.27Å; E644-K647 VanDerWaalsContact O-N 3.13Å; E644-S648 PolarHBondContact O-N 3.49Å; E644-S648 PolarHBondContact O-OG 3Å
645F78.2Confident83Confident140 Ų140122.6 Ų122.661%0.61459%0.591SS**Hα-helixtrans-58.8-46.7174.5-174.7-100.1000111.4E641 K647 S648 V649E641-F645 WeakPolarHBondContact O-CB 3.44Å; E641-F645 PolarHBondContact O-N 3.45Å; F645-K647 VanDerWaalsContact C-N 3.3Å; F645-K647 PolarHBondContact O-N 2.81Å; F645-S648 WeakPolarHBondContact CA-OG 3.38Å; F645-S648 PolarHBondContact O-N 3.32Å; F645-S648 VanDerWaalsContact O-N 3.12Å; F645-S648 PolarHBondContact O-OG 3.39Å; F645-V649 HydrophobicContact CD1-CG2 4.27Å; F645-V649 HydrophobicContact CE1-CG2 3.91Å; F645-V649 HydrophobicContact CE2-CG2 4.26Å; F645-V649 HydrophobicContact CZ-CG2 3.91Å; F645-V649 VanDerWaalsContact O-CG2 3.3Å; F645-V649 WeakPolarHBondContact O-CG2 3.44Å; F645-V649 PolarHBondContact O-N 2.9Å; F645-V649 VanDerWaalsContact O-N 3.14Å
646R75.8Confident82.3Confident189 Ų189121.3 Ų121.371%0.71359%0.59SS**Hα-helixtrans-60.2-37.8175.2-76.8177-176.2-176.61.9113G642 T643 E644 Q650G642-R646 VanDerWaalsContact O-CG 3.32Å; G642-R646 WeakPolarHBondContact O-CG 3.04Å; G642-R646 PolarHBondContact O-N 2.87Å; G642-R646 VanDerWaalsContact O-N 3.11Å; T643-R646 PolarHBondContact O-N 3.31Å; E644-R646 PolarHBondContact O-N 3.09Å; R646-Q650 PolarHBondContact O-N 2.59Å
647K76.7Confident81.5Confident150 Ų150122.6 Ų122.665%0.65260%0.6SS**Hα-helixtrans-71.5-27.1175.3-75.1179.9177.9-178.60113.5T643 E644 F645T643-K647 WeakPolarHBondContact O-CG 3.31Å; T643-K647 PolarHBondContact O-N 3.4Å; E644-K647 CarbonylContact O-C 3.59Å; E644-K647 PolarHBondContact O-N 3.27Å; E644-K647 VanDerWaalsContact O-N 3.13Å; F645-K647 VanDerWaalsContact C-N 3.3Å; F645-K647 PolarHBondContact O-N 2.81Å
648S73Confident80.7Confident85 Ų85122.4 Ų122.459%0.59460%0.604SS**Hα-helixtrans-81-18.6176.969.20000113.8E644 F645E644-S648 PolarHBondContact O-N 3.49Å; E644-S648 PolarHBondContact O-OG 3Å; F645-S648 WeakPolarHBondContact CA-OG 3.38Å; F645-S648 PolarHBondContact O-N 3.32Å; F645-S648 VanDerWaalsContact O-N 3.12Å; F645-S648 PolarHBondContact O-OG 3.39Å
649V72.9Confident79.8Confident104 Ų104121.5 Ų121.563%0.6361%0.606SS**Hα-helixtrans-96.5-17.7-179.9176.40000112F645F645-V649 HydrophobicContact CD1-CG2 4.27Å; F645-V649 HydrophobicContact CE1-CG2 3.91Å; F645-V649 HydrophobicContact CE2-CG2 4.26Å; F645-V649 HydrophobicContact CZ-CG2 3.91Å; F645-V649 VanDerWaalsContact O-CG2 3.3Å; F645-V649 WeakPolarHBondContact O-CG2 3.44Å; F645-V649 PolarHBondContact O-N 2.9Å; F645-V649 VanDerWaalsContact O-N 3.14Å
650Q61.6Low78.9Confident216 Ų216121.1 Ų121.1100%1.00961%0.605SS**  trans-87.70167.8-74-177.5-19.600110.2R646R646-Q650 PolarHBondContact O-N 2.59Å

Retrieved 650 of 650 residues in 845.3 ms (Link to these results)