A0A087XQW3_POEFO Loading...

Occludin a

AlphaFold DB , UniProt , Accession A0A087XQW3, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 511 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.8	Very low	39.6	Very low	238 Å²	238	130.2 Å²	130.2	100%	1.172	80%	0.804	S	S	*	*				0	146.4	0	-76.9	170.7	157.8	0	0	108.3
2	S	34.4	Very low	39.8	Very low	118 Å²	118	138.1 Å²	138.1	83%	0.825	81%	0.81	S	S	*	*			trans	47.6	145.3	158.7	-77.3	0	0	0	0	121.6
3	S	40.8	Very low	39.6	Very low	108 Å²	108	141.8 Å²	141.8	76%	0.755	82%	0.815	S	S	*	*			cis	-165.7	159.4	-19.2	38.4	0	0	0	0	109.2
4	K	40.2	Very low	39.6	Very low	176 Å²	176	145.2 Å²	145.2	77%	0.765	82%	0.82	S	S	*	*			trans	-63.9	162.3	168.8	-109.8	178.2	178.8	-178.1	0	111
5	P	45.2	Very low	39.5	Very low	122 Å²	122	146.3 Å²	146.3	79%	0.792	82%	0.823	S	S	*	*				-140.5	177	51.3	40.6	-22	0	0	0	117.6
6	N	40.1	Very low	39.7	Very low	141 Å²	141	146.1 Å²	146.1	75%	0.754	82%	0.819	S	S	*	*			trans	-80.6	154.1	168.8	-59.8	12.1	0	0	0	110.4
7	G	35.7	Very low	39.7	Very low	75 Å²	75	150.4 Å²	150.4	77%	0.773	82%	0.82	S	S	*	*			trans	-126.4	157.6	166.5	0	0	0	0	0	111.2
8	S	40.2	Very low	39.3	Very low	115 Å²	115	154.5 Å²	154.5	80%	0.804	82%	0.823	S	S	*	*	P	Polyproline II helix	trans	-66.1	155.9	-170.6	-50.1	0	0	0	0	114.7
9	P	42.3	Very low	39.5	Very low	114 Å²	114	155.9 Å²	155.9	74%	0.74	83%	0.831	S	S	*	*	P	Polyproline II helix	trans	-64.2	157.7	157.6	31.1	-35	0	0	0	110.9
10	P	44.7	Very low	39.7	Very low	108 Å²	108	150.3 Å²	150.3	70%	0.701	81%	0.811	S	S	*	*	P	Polyproline II helix	trans	-71.1	161.1	-177.4	30.5	-36.3	0	0	0	113
11	P	38.2	Very low	39.8	Very low	117 Å²	117	148.9 Å²	148.9	76%	0.76	81%	0.81	S	S	*	*	P	Polyproline II helix	trans	-66.5	150.1	170	30.8	-35.2	0	0	0	110.9
12	Y	42.2	Very low	39.9	Very low	225 Å²	225	142.5 Å²	142.5	88%	0.882	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-80	131.5	168.8	-61.8	-88	0	0	0	108.9
13	E	37	Very low	39.8	Very low	187 Å²	187	145.3 Å²	145.3	87%	0.874	80%	0.795	S	S	*	*	P	Polyproline II helix	trans	-81.1	132.3	172	-63.9	-179.3	136.1	0	0	109.3	D15	E13-D15 PolarHBondContact O-N 3.12Å
14	E	39.8	Very low	39.5	Very low	189 Å²	189	146 Å²	146	88%	0.883	80%	0.797	S	S	*	*			trans	-81.4	94.2	179.6	-66.8	-178.2	138	0	0	109.9	D16	E14-D16 VanDerWaalsContact C-N 3.34Å; E14-D16 PolarHBondContact O-N 2.96Å
15	D	37.3	Very low	39.1	Very low	162 Å²	162	142.7 Å²	142.7	87%	0.866	80%	0.803	S	S	*	*			trans	-80.5	80.3	-174.8	-150.9	-2.3	0	0	0	111.8	E13 R17	E13-D15 PolarHBondContact O-N 3.12Å; D15-R17 PolarHBondContact O-N 3.19Å
16	D	43.5	Very low	38.5	Very low	142 Å²	142	147 Å²	147	76%	0.759	81%	0.805	S	S	*	*			trans	-73.3	81.9	-170.6	-155	4.7	0	0	0	112.6	E14	E14-D16 VanDerWaalsContact C-N 3.34Å; E14-D16 PolarHBondContact O-N 2.96Å
17	R	39.7	Very low	38.3	Very low	220 Å²	220	143.8 Å²	143.8	83%	0.83	79%	0.793	S	S	*	*			trans	-169.6	85.4	160.5	-115.8	159.4	-69.1	-179.2	2.5	116.7	D15	D15-R17 PolarHBondContact O-N 3.19Å
18	Y	32.9	Very low	38.2	Very low	224 Å²	224	150.2 Å²	150.2	88%	0.878	80%	0.796	S	S	*	*			trans	-151	72.9	149.8	-141.9	-89.4	0	0	0	114.7	G20	Y18-G20 PolarHBondContact O-N 3Å
19	N	42.5	Very low	38.1	Very low	181 Å²	181	152.6 Å²	152.6	97%	0.968	79%	0.788	S	S	*	*			trans	-71.3	76.6	170.1	-96.7	-23.1	0	0	0	111.6
20	G	44.3	Very low	37.7	Very low	43 Å²	43	152.4 Å²	152.4	44%	0.443	79%	0.787	S	S	.	*			trans	-80.8	148.7	161.4	0	0	0	0	0	111	Y18 A22	Y18-G20 PolarHBondContact O-N 3Å; G20-A22 PolarHBondContact O-N 3.07Å
21	P	40.2	Very low	37.4	Very low	122 Å²	122	152.3 Å²	152.3	79%	0.792	78%	0.781	S	S	*	*			trans	-62.8	133.1	173.2	27.5	-33.8	0	0	0	109.9	Q23	P21-Q23 PolarHBondContact O-N 2.92Å
22	A	36.3	Very low	37.6	Very low	104 Å²	104	151.1 Å²	151.1	86%	0.86	77%	0.768	S	S	*	*			trans	-56.8	112.6	-178.5	0	0	0	0	0	110.8	G20	G20-A22 PolarHBondContact O-N 3.07Å
23	Q	32.6	Very low	37.7	Very low	176 Å²	176	145.8 Å²	145.8	82%	0.822	75%	0.751	S	S	*	*			trans	-74.7	135.5	174.1	-61.3	-160.3	11.3	0	0	108.9	P21 A25	P21-Q23 PolarHBondContact O-N 2.92Å; Q23-A25 PolarHBondContact O-N 3.4Å
24	P	34.9	Very low	38.3	Very low	122 Å²	122	141.5 Å²	141.5	79%	0.792	73%	0.73	S	S	*	*			trans	-61	129.5	176	26.2	-33.6	0	0	0	109.1	Y26	P24-Y26 PolarHBondContact O-N 2.85Å
25	A	32.1	Very low	38.9	Very low	107 Å²	107	133.9 Å²	133.9	88%	0.884	69%	0.694	S	S	*	*			trans	-61.6	101.1	-172.1	0	0	0	0	0	111.6	Q23 S27	Q23-A25 PolarHBondContact O-N 3.4Å; A25-S27 PolarHBondContact O-N 3.08Å
26	Y	32.6	Very low	39.8	Very low	213 Å²	213	131.3 Å²	131.3	84%	0.835	68%	0.677	S	S	*	*			trans	-77.8	107.2	173.5	-168.2	-82	0	0	0	108.5	P24 Y28	P24-Y26 PolarHBondContact O-N 2.85Å; Y26-Y28 PolarHBondContact O-N 3.24Å; Y26-Y28 VanDerWaalsContact O-N 3.16Å
27	S	35.3	Very low	40.6	Very low	73 Å²	73	125 Å²	125	51%	0.51	64%	0.642	S	S	.	*			trans	-65.6	114.9	-175.5	50.3	0	0	0	0	111.4	A25 Y29	A25-S27 PolarHBondContact O-N 3.08Å; S27-Y29 PolarHBondContact O-N 3.14Å
28	Y	34	Very low	41.3	Very low	210 Å²	210	119.4 Å²	119.4	82%	0.824	62%	0.622	S	S	*	*			trans	-84.4	57.1	178.3	-169.9	-103.5	0	0	0	111.3	Y26	Y26-Y28 PolarHBondContact O-N 3.24Å; Y26-Y28 VanDerWaalsContact O-N 3.16Å
29	Y	37.8	Very low	42.6	Very low	166 Å²	166	117.7 Å²	117.7	65%	0.651	61%	0.614	S	S	*	*			trans	-108.6	106.9	170.4	-75.8	-70.3	0	0	0	109.6	S27 D31 D32	S27-Y29 PolarHBondContact O-N 3.14Å; Y29-D31 PolarHBondContact O-N 3.4Å; Y29-D31 VanDerWaalsContact O-N 3.15Å; Y29-D32 PolarHBondContact O-N 2.87Å
30	P	34.8	Very low	43.1	Very low	109 Å²	109	116.7 Å²	116.7	71%	0.708	60%	0.597	S	S	*	*	T	Hydrogen-bonded Turn	trans	-62	-17.6	176.2	-25.7	36.4	0	0	0	114.6
31	D	37.8	Very low	43.8	Very low	107 Å²	107	119 Å²	119	57%	0.572	61%	0.607	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89	-6.4	-176.3	-63.4	-53	0	0	0	114.2	Y29 E33	Y29-D31 PolarHBondContact O-N 3.4Å; Y29-D31 VanDerWaalsContact O-N 3.15Å; D31-E33 VanDerWaalsContact C-N 3.26Å; D31-E33 PolarHBondContact O-N 3.04Å
32	D	41.8	Very low	45.1	Very low	91 Å²	91	113.6 Å²	113.6	49%	0.487	57%	0.571	S	S	.	*			trans	-81	24.2	-164.3	-113.6	-15.5	0	0	0	116.3	Y29 F34	Y29-D32 PolarHBondContact O-N 2.87Å; D32-F34 VanDerWaalsContact C-N 3.32Å; D32-F34 PolarHBondContact O-N 3.3Å
33	E	45.6	Very low	46.8	Very low	114 Å²	114	109.6 Å²	109.6	53%	0.533	54%	0.536	S	S	.	.			trans	-95.4	46.7	164.4	-106.4	-128	148	0	0	111.9	D31 Q35 K263	D31-E33 VanDerWaalsContact C-N 3.26Å; D31-E33 PolarHBondContact O-N 3.04Å; E33-Q35 PolarHBondContact O-N 3.34Å; E33-K263 IonicContact OE1-NZ 3.68Å; E33-K263 IonicContact OE2-NZ 2.81Å; E33-K263 PolarHBondContact OE2-NZ 2.75Å
34	F	48.6	Very low	48.8	Very low	96 Å²	96	101.3 Å²	101.3	42%	0.421	50%	0.498	S	S	.	.			trans	-49.3	111.2	163.7	-79.8	-71.9	0	0	0	109.5	D32 H36 L273	D32-F34 VanDerWaalsContact C-N 3.32Å; D32-F34 PolarHBondContact O-N 3.3Å; F34-H36 PolarHBondContact O-N 3.37Å; F34-H36 PolarHBondContact O-ND1 2.98Å; F34-L273 HydrophobicContact CB-CD1 4.14Å
35	Q	52.8	Low	50.7	Low	29 Å²	29	95.7 Å²	95.7	14%	0.136	46%	0.462	C	S	.	.	B	Isolated β-bridge	trans	-81.8	96	-165.9	-172.6	65.1	92.3	0	0	110.3	E33 F37 K263 N271 L273	E33-Q35 PolarHBondContact O-N 3.34Å; Q35-F37 VanDerWaalsContact C-N 3.27Å; Q35-F37 HydrophobicContact CB-CE1 4.44Å; Q35-F37 HydrophobicContact CG-CD1 3.52Å; Q35-F37 HydrophobicContact CG-CE1 3.29Å; Q35-F37 HydrophobicContact CG-CZ 4.14Å; Q35-F37 PolarHBondContact O-N 2.6Å; Q35-K263 HydrophobicContact CG-CD 4.16Å; Q35-K263 VanDerWaalsContact OE1-CE 3.25Å; Q35-N271 PolarHBondContact N-O 2.96Å; Q35-L273 PolarHBondContact O-N 3.37Å
36	H	55.5	Low	53.1	Low	109 Å²	109	92.4 Å²	92.4	51%	0.505	43%	0.429	S	S	.	.			trans	-67	69.6	-176.2	-75.1	79.3	0	0	0	114	F34 Y38 R39 S42	F34-H36 PolarHBondContact O-N 3.37Å; F34-H36 PolarHBondContact O-ND1 2.98Å; H36-Y38 PolarHBondContact O-N 3.45Å; H36-Y38 VanDerWaalsContact O-N 3.09Å; H36-R39 PolarHBondContact O-N 3.33Å; H36-S42 VanDerWaalsContact O-CB 3.27Å; H36-S42 WeakPolarHBondContact O-CB 3.21Å
37	F	60.9	Low	55.5	Low	9 Å²	9	82.5 Å²	82.5	4%	0.039	39%	0.391	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64.3	-8	-179.1	-85.2	1.7	0	0	0	115.4	Q35 S42 P43 P44 T260 I264 I272 L273 W274	Q35-F37 VanDerWaalsContact C-N 3.27Å; Q35-F37 HydrophobicContact CB-CE1 4.44Å; Q35-F37 HydrophobicContact CG-CD1 3.52Å; Q35-F37 HydrophobicContact CG-CE1 3.29Å; Q35-F37 HydrophobicContact CG-CZ 4.14Å; Q35-F37 PolarHBondContact O-N 2.6Å; F37-S42 WeakPolarHBondContact CA-OG 3.5Å; F37-S42 PolarHBondContact O-OG 3.23Å; F37-P43 HydrophobicContact CE1-CB 4.22Å; F37-P43 HydrophobicContact CE1-CG 4.06Å; F37-P44 HydrophobicContact CB-CG 3.63Å; F37-P44 HydrophobicContact CD1-CG 3.66Å; F37-P44 HydrophobicContact CD2-CG 3.82Å; F37-P44 HydrophobicContact CE1-CG 4.22Å; F37-P44 HydrophobicContact CE2-CG 4.37Å; F37-P44 HydrophobicContact CG-CG 3.43Å; F37-P44 VanDerWaalsContact CG-CG 3.43Å; F37-T260 HydrophobicContact CE2-CG2 4.02Å; F37-T260 HydrophobicContact CZ-CG2 3.88Å; F37-I264 HydrophobicContact CE2-CD1 4Å; F37-I264 HydrophobicContact CE2-CG1 3.81Å; F37-I264 HydrophobicContact CZ-CG1 4.27Å; F37-I272 HydrophobicContact CD2-CG2 3.24Å; F37-I272 HydrophobicContact CE2-CG2 3.47Å; F37-I272 VanDerWaalsContact CE2-CG2 3.47Å; F37-I272 HydrophobicContact CG-CG2 3.92Å; F37-I272 HydrophobicContact CZ-CG2 4.31Å; F37-L273 PolarHBondContact N-O 2.9Å; F37-W274 HydrophobicContact CB-CE3 4.33Å; F37-W274 HydrophobicContact CD2-CD2 4.01Å; F37-W274 AromaticContact CD2-CE2 3.87Å; F37-W274 AromaticContact CD2-CE3 3.91Å; F37-W274 HydrophobicContact CD2-CE3 3.91Å; F37-W274 AromaticContact CD2-CH2 3.52Å; F37-W274 HydrophobicContact CD2-CH2 3.52Å; F37-W274 AromaticContact CD2-CZ2 3.64Å; F37-W274 HydrophobicContact CD2-CZ2 3.64Å; F37-W274 AromaticContact CD2-CZ3 3.67Å; F37-W274 HydrophobicContact CD2-CZ3 3.67Å; F37-W274 AromaticContact CE2-CH2 3.68Å; F37-W274 HydrophobicContact CE2-CH2 3.68Å; F37-W274 AromaticContact CE2-CZ2 3.74Å; F37-W274 HydrophobicContact CE2-CZ2 3.74Å; F37-W274 HydrophobicContact CE2-CZ3 4.27Å
38	Y	54.5	Low	57.9	Low	103 Å²	103	80.6 Å²	80.6	40%	0.404	37%	0.373	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.7	-28.6	167.4	-177.1	-86.4	0	0	0	113.7	H36 L273 K276	H36-Y38 PolarHBondContact O-N 3.45Å; H36-Y38 VanDerWaalsContact O-N 3.09Å; Y38-L273 PolarHBondContact N-O 3.21Å; Y38-K276 HydrophobicContact CD1-CB 3.72Å; Y38-K276 HydrophobicContact CD1-CD 3.8Å; Y38-K276 HydrophobicContact CD1-CG 3.45Å; Y38-K276 VanDerWaalsContact CD1-CG 3.45Å; Y38-K276 HydrophobicContact CD2-CB 3.86Å; Y38-K276 HydrophobicContact CE1-CB 3.87Å; Y38-K276 HydrophobicContact CE1-CD 3.51Å; Y38-K276 HydrophobicContact CE1-CG 3.69Å; Y38-K276 HydrophobicContact CE2-CB 3.99Å; Y38-K276 HydrophobicContact CG-CB 3.7Å; Y38-K276 HydrophobicContact CG-CG 3.9Å; Y38-K276 VanDerWaalsContact CG-N 3.34Å
39	R	59.3	Low	60.4	Low	188 Å²	188	73.4 Å²	73.4	71%	0.709	35%	0.349	S	S	*	.	S	Bend	trans	-67.2	137.7	-174.8	-163.6	172.2	-175.9	170.5	0.7	109.6	H36 S41 S42	H36-R39 PolarHBondContact O-N 3.33Å; R39-S41 PolarHBondContact O-N 3.47Å; R39-S41 VanDerWaalsContact O-N 3.15Å; R39-S42 WeakPolarHBondContact O-CB 3.3Å; R39-S42 PolarHBondContact O-N 3.41Å; R39-S42 PolarHBondContact O-OG 3.32Å
40	W	53.9	Low	62.8	Low	159 Å²	159	66.8 Å²	66.8	60%	0.602	32%	0.324	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.3	-25.5	-177.2	-76.3	64.6	0	0	0	113.1	S42 G45 I46 I49	W40-S42 VanDerWaalsContact C-N 3.32Å; W40-G45 CarbonylContact O-C 3.58Å; W40-G45 WeakPolarHBondContact O-CA 3.38Å; W40-I46 PolarHBondContact O-N 2.75Å; W40-I49 HydrophobicContact CB-CD1 4.48Å; W40-I49 HydrophobicContact CE3-CD1 4.11Å; W40-I49 HydrophobicContact CE3-CG1 3.84Å; W40-I49 HydrophobicContact CZ3-CG1 4.26Å
41	S	58.1	Low	65.3	Low	93 Å²	93	61.6 Å²	61.6	65%	0.65	29%	0.29	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.4	3	172.6	-167.8	0	0	0	0	114.6	R39	R39-S41 PolarHBondContact O-N 3.47Å; R39-S41 VanDerWaalsContact O-N 3.15Å
42	S	67.7	Low	67.9	Low	7 Å²	7	59.5 Å²	59.5	5%	0.049	28%	0.278	C	S	.	.	S	Bend	trans	-80.3	162.3	177	72.9	0	0	0	0	111.6	H36 F37 R39 W40 G45 I46	H36-S42 VanDerWaalsContact O-CB 3.27Å; H36-S42 WeakPolarHBondContact O-CB 3.21Å; F37-S42 WeakPolarHBondContact CA-OG 3.5Å; F37-S42 PolarHBondContact O-OG 3.23Å; R39-S42 WeakPolarHBondContact O-CB 3.3Å; R39-S42 PolarHBondContact O-N 3.41Å; R39-S42 PolarHBondContact O-OG 3.32Å; W40-S42 VanDerWaalsContact C-N 3.32Å; S42-G45 CarbonylContact O-C 3.57Å; S42-G45 WeakPolarHBondContact O-CA 3.13Å; S42-G45 PolarHBondContact O-N 2.8Å; S42-G45 PolarHBondContact OG-N 3.29Å; S42-I46 WeakPolarHBondContact O-CG1 3.48Å; S42-I46 PolarHBondContact O-N 2.91Å
43	P	72.6	Confident	70.3	Confident	20 Å²	20	58.7 Å²	58.7	13%	0.13	27%	0.273	C	S	.	.	H	α-helix	trans	-50.5	-46.9	179.2	-28.4	36.1	0	0	0	115.6	F37 L47 F256 T260	F37-P43 HydrophobicContact CE1-CB 4.22Å; F37-P43 HydrophobicContact CE1-CG 4.06Å; P43-L47 WeakPolarHBondContact O-CG 3.46Å; P43-L47 PolarHBondContact O-N 2.7Å; P43-F256 HydrophobicContact CB-CD1 4.46Å; P43-T260 WeakPolarHBondContact CB-OG1 3.17Å
44	P	74.3	Confident	72.5	Confident	3 Å²	3	53.2 Å²	53.2	2%	0.019	25%	0.248	C	C	.	.	H	α-helix	trans	-77.2	-23.2	172.9	31	-35.8	0	0	0	114	F37 L47 K48 I153	F37-P44 HydrophobicContact CB-CG 3.63Å; F37-P44 HydrophobicContact CD1-CG 3.66Å; F37-P44 HydrophobicContact CD2-CG 3.82Å; F37-P44 HydrophobicContact CE1-CG 4.22Å; F37-P44 HydrophobicContact CE2-CG 4.37Å; F37-P44 HydrophobicContact CG-CG 3.43Å; F37-P44 VanDerWaalsContact CG-CG 3.43Å; P44-L47 PolarHBondContact O-N 3.23Å; P44-K48 PolarHBondContact O-N 3.39Å; P44-K48 VanDerWaalsContact O-N 3.1Å; P44-I153 HydrophobicContact CB-CG2 4.43Å
45	G	75.1	Confident	74.7	Confident	4 Å²	4	49.9 Å²	49.9	4%	0.041	23%	0.234	C	C	.	.	H	α-helix	trans	-64	-44.9	170.6	0	0	0	0	0	111.9	W40 S42 L47 K48 I49	W40-G45 CarbonylContact O-C 3.58Å; W40-G45 WeakPolarHBondContact O-CA 3.38Å; S42-G45 CarbonylContact O-C 3.57Å; S42-G45 WeakPolarHBondContact O-CA 3.13Å; S42-G45 PolarHBondContact O-N 2.8Å; S42-G45 PolarHBondContact OG-N 3.29Å; G45-L47 VanDerWaalsContact C-N 3.31Å; G45-L47 PolarHBondContact O-N 3.37Å; G45-K48 WeakPolarHBondContact O-CB 3.47Å; G45-K48 PolarHBondContact O-N 3.29Å; G45-K48 VanDerWaalsContact O-N 3.1Å; G45-I49 WeakPolarHBondContact O-CG1 3.49Å; G45-I49 PolarHBondContact O-N 2.85Å; G45-I49 VanDerWaalsContact O-N 3.11Å
46	I	81.9	Confident	76.7	Confident	37 Å²	37	53 Å²	53	19%	0.19	26%	0.255	C	S	.	.	H	α-helix	trans	-62.9	-38.7	174	-64.8	165.5	0	0	0	110.3	W40 S42 K48 I49 M50 F256	W40-I46 PolarHBondContact O-N 2.75Å; S42-I46 WeakPolarHBondContact O-CG1 3.48Å; S42-I46 PolarHBondContact O-N 2.91Å; I46-K48 VanDerWaalsContact C-N 3.33Å; I46-K48 PolarHBondContact O-N 3.39Å; I46-I49 PolarHBondContact O-N 3.12Å; I46-M50 HydrophobicContact CG2-CG 4.1Å; I46-M50 WeakPolarHBondContact O-CG 3.48Å; I46-M50 PolarHBondContact O-N 3.36Å; I46-F256 HydrophobicContact CB-CD1 4.37Å; I46-F256 HydrophobicContact CB-CE1 4.45Å; I46-F256 HydrophobicContact CB-CG 4.49Å; I46-F256 HydrophobicContact CD1-CD1 4.2Å; I46-F256 HydrophobicContact CD1-CE1 3.55Å; I46-F256 HydrophobicContact CD1-CZ 3.82Å; I46-F256 HydrophobicContact CG2-CD1 4.22Å; I46-F256 HydrophobicContact CG2-CD2 3.73Å; I46-F256 HydrophobicContact CG2-CE1 4.21Å; I46-F256 HydrophobicContact CG2-CE2 3.73Å; I46-F256 HydrophobicContact CG2-CG 3.99Å; I46-F256 HydrophobicContact CG2-CZ 3.98Å
47	L	83.2	Confident	78.5	Confident	5 Å²	5	48.8 Å²	48.8	3%	0.026	24%	0.236	C	C	.	.	H	α-helix	trans	-60	-38.3	172.3	-70.9	173.8	0	0	0	112.9	P43 P44 G45 A51 I153 Y166 M253 F256 A257	P43-L47 WeakPolarHBondContact O-CG 3.46Å; P43-L47 PolarHBondContact O-N 2.7Å; P44-L47 PolarHBondContact O-N 3.23Å; G45-L47 VanDerWaalsContact C-N 3.31Å; G45-L47 PolarHBondContact O-N 3.37Å; L47-A51 VanDerWaalsContact O-CB 3.28Å; L47-A51 WeakPolarHBondContact O-CB 3.25Å; L47-A51 PolarHBondContact O-N 2.95Å; L47-I153 HydrophobicContact CB-CD1 4.08Å; L47-Y166 HydrophobicContact CD1-CD1 4.41Å; L47-Y166 HydrophobicContact CD1-CE1 3.87Å; L47-M253 HydrophobicContact CD2-CB 3.88Å; L47-M253 HydrophobicContact CD2-CG 3.94Å; L47-M253 WeakPolarHBondContact CD2-O 3.45Å; L47-F256 HydrophobicContact CD2-CB 3.78Å; L47-F256 HydrophobicContact CG-CB 4.02Å; L47-A257 HydrophobicContact CD1-CB 4.47Å
48	K	84.9	Confident	80.1	Confident	33 Å²	33	48.6 Å²	48.6	14%	0.143	24%	0.236	C	C	.	.	H	α-helix	trans	-61.6	-46.8	172.1	-66	-178.5	-179.6	-170.5	0	111.3	P44 G45 I46 A51 I52 I153 V154 H156	P44-K48 PolarHBondContact O-N 3.39Å; P44-K48 VanDerWaalsContact O-N 3.1Å; G45-K48 WeakPolarHBondContact O-CB 3.47Å; G45-K48 PolarHBondContact O-N 3.29Å; G45-K48 VanDerWaalsContact O-N 3.1Å; I46-K48 VanDerWaalsContact C-N 3.33Å; I46-K48 PolarHBondContact O-N 3.39Å; K48-A51 PolarHBondContact O-N 3.45Å; K48-I52 WeakPolarHBondContact O-CG1 3.49Å; K48-I52 PolarHBondContact O-N 2.72Å; K48-I153 HydrophobicContact CD-CG2 4.3Å; K48-I153 VanDerWaalsContact CE-CG2 3.45Å; K48-I153 WeakPolarHBondContact CE-O 3.43Å; K48-I153 HydrophobicContact CG-CB 4.19Å; K48-I153 HydrophobicContact CG-CG2 3.82Å; K48-I153 PolarHBondContact NZ-O 3.38Å; K48-I153 VanDerWaalsContact NZ-O 3.08Å; K48-V154 HydrophobicContact CD-CG2 4.05Å; K48-V154 HydrophobicContact CG-CG2 4.39Å; K48-H156 PolarHBondContact NZ-NE2 2.91Å; K48-H156 VanDerWaalsContact NZ-NE2 3.1Å
49	I	87.7	Confident	82	Confident	60 Å²	60	47.5 Å²	47.5	31%	0.308	24%	0.24	S	C	.	.	H	α-helix	trans	-61.9	-48.4	-179.2	-63.8	165.5	0	0	0	110.8	W40 G45 I46 A51 I52 I53	W40-I49 HydrophobicContact CB-CD1 4.48Å; W40-I49 HydrophobicContact CE3-CD1 4.11Å; W40-I49 HydrophobicContact CE3-CG1 3.84Å; W40-I49 HydrophobicContact CZ3-CG1 4.26Å; G45-I49 WeakPolarHBondContact O-CG1 3.49Å; G45-I49 PolarHBondContact O-N 2.85Å; G45-I49 VanDerWaalsContact O-N 3.11Å; I46-I49 PolarHBondContact O-N 3.12Å; I49-A51 VanDerWaalsContact C-N 3.32Å; I49-A51 PolarHBondContact O-N 3.08Å; I49-I52 PolarHBondContact O-N 3.35Å; I49-I53 HydrophobicContact CG2-CD1 3.87Å; I49-I53 WeakPolarHBondContact O-CG1 3.44Å; I49-I53 PolarHBondContact O-N 3.35Å
50	M	87.7	Confident	83.6	Confident	27 Å²	27	40 Å²	40	13%	0.133	22%	0.217	C	C	.	.	H	α-helix	trans	-66.4	-33.3	179.6	-63.3	-53.8	-58.9	0	0	112.5	I46 I53 T54 A249 I252 M253	I46-M50 HydrophobicContact CG2-CG 4.1Å; I46-M50 WeakPolarHBondContact O-CG 3.48Å; I46-M50 PolarHBondContact O-N 3.36Å; M50-I53 PolarHBondContact O-N 3.09Å; M50-I53 HydrophobicContact SD-CD1 4.19Å; M50-T54 WeakPolarHBondContact O-CB 3.4Å; M50-T54 PolarHBondContact O-N 3.11Å; M50-T54 PolarHBondContact O-OG1 2.95Å; M50-A249 HydrophobicContact CE-CB 3.68Å; M50-I252 HydrophobicContact CE-CB 4.11Å; M50-I252 HydrophobicContact CE-CD1 4.01Å; M50-I252 HydrophobicContact CE-CG2 3.94Å; M50-I252 HydrophobicContact CG-CG2 3.97Å; M50-I252 HydrophobicContact SD-CG2 4.12Å; M50-M253 HydrophobicContact CB-CG 3.48Å; M50-M253 VanDerWaalsContact CB-CG 3.48Å; M50-M253 HydrophobicContact CB-SD 3.97Å; M50-M253 HydrophobicContact CG-CG 4.38Å
51	A	88.4	Confident	85.4	Confident	0 Å²	0	32.4 Å²	32.4	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-66	-42.6	172.4	0	0	0	0	0	112	L47 K48 I49 T54 L55 F150 M253	L47-A51 VanDerWaalsContact O-CB 3.28Å; L47-A51 WeakPolarHBondContact O-CB 3.25Å; L47-A51 PolarHBondContact O-N 2.95Å; K48-A51 PolarHBondContact O-N 3.45Å; I49-A51 VanDerWaalsContact C-N 3.32Å; I49-A51 PolarHBondContact O-N 3.08Å; A51-T54 PolarHBondContact O-N 3.29Å; A51-L55 VanDerWaalsContact O-CG 3.3Å; A51-L55 WeakPolarHBondContact O-CG 3.43Å; A51-L55 PolarHBondContact O-N 2.73Å; A51-F150 HydrophobicContact CB-CB 4.2Å; A51-M253 HydrophobicContact CB-SD 4.17Å
52	I	91	Very high	87	Confident	62 Å²	62	33 Å²	33	32%	0.318	18%	0.18	S	C	.	.	H	α-helix	trans	-59.5	-48.5	173.3	-65.9	159.9	0	0	0	110.7	K48 I49 T54 L55 V56 F150	K48-I52 WeakPolarHBondContact O-CG1 3.49Å; K48-I52 PolarHBondContact O-N 2.72Å; I49-I52 PolarHBondContact O-N 3.35Å; I52-T54 VanDerWaalsContact C-N 3.3Å; I52-T54 PolarHBondContact O-N 3.31Å; I52-L55 PolarHBondContact O-N 2.97Å; I52-V56 HydrophobicContact CG2-CG2 4.5Å; I52-V56 WeakPolarHBondContact O-CG2 3.49Å; I52-V56 PolarHBondContact O-N 2.85Å; I52-F150 HydrophobicContact CD1-CE2 3.73Å; I52-F150 HydrophobicContact CD1-CZ 4.39Å; I52-F150 HydrophobicContact CG1-CD2 3.89Å; I52-F150 HydrophobicContact CG1-CE2 3.42Å; I52-F150 VanDerWaalsContact CG1-CE2 3.42Å; I52-F150 HydrophobicContact CG1-CZ 4.09Å
53	I	92.4	Very high	88.1	Confident	74 Å²	74	35.4 Å²	35.4	38%	0.379	20%	0.2	S	C	.	.	H	α-helix	trans	-58.9	-43.8	178.3	-68.4	167.4	0	0	0	110.5	I49 M50 L55 V56 L57	I49-I53 HydrophobicContact CG2-CD1 3.87Å; I49-I53 WeakPolarHBondContact O-CG1 3.44Å; I49-I53 PolarHBondContact O-N 3.35Å; M50-I53 PolarHBondContact O-N 3.09Å; M50-I53 HydrophobicContact SD-CD1 4.19Å; I53-L55 PolarHBondContact O-N 3.19Å; I53-V56 PolarHBondContact O-N 3.35Å; I53-L57 HydrophobicContact CG2-CD1 3.81Å; I53-L57 HydrophobicContact CG2-CG 4.35Å; I53-L57 WeakPolarHBondContact O-CB 3.3Å; I53-L57 VanDerWaalsContact O-CG 3.3Å; I53-L57 WeakPolarHBondContact O-CG 3.44Å; I53-L57 PolarHBondContact O-N 3.2Å
54	T	92.8	Very high	89	Confident	0 Å²	0	35.5 Å²	35.5	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-62.6	-42.3	177.9	-53.7	0	0	0	0	111.6	M50 A51 I52 L57 C58 V142 S146 V246 A249 M253	M50-T54 WeakPolarHBondContact O-CB 3.4Å; M50-T54 PolarHBondContact O-N 3.11Å; M50-T54 PolarHBondContact O-OG1 2.95Å; A51-T54 PolarHBondContact O-N 3.29Å; I52-T54 VanDerWaalsContact C-N 3.3Å; I52-T54 PolarHBondContact O-N 3.31Å; T54-L57 PolarHBondContact O-N 3.01Å; T54-C58 WeakPolarHBondContact O-CB 3.36Å; T54-C58 PolarHBondContact O-N 3.21Å; T54-C58 PolarHBondContact O-SG 3.33Å; T54-C58 VanDerWaalsContact O-SG 3.39Å; T54-V142 HydrophobicContact CG2-CG1 3.69Å; T54-S146 WeakPolarHBondContact CG2-OG 3.45Å; T54-V246 HydrophobicContact CG2-CG1 4.17Å; T54-A249 WeakPolarHBondContact OG1-CB 3.37Å; T54-M253 HydrophobicContact CG2-CE 4.38Å; T54-M253 WeakPolarHBondContact OG1-CE 3.28Å
55	L	93.9	Very high	89.6	Confident	25 Å²	25	35.4 Å²	35.4	13%	0.131	20%	0.2	C	C	.	.	H	α-helix	trans	-61.7	-46.4	176.1	-72.5	167.3	0	0	0	112.4	A51 I52 I53 C58 V59 F143 L147 F150	A51-L55 VanDerWaalsContact O-CG 3.3Å; A51-L55 WeakPolarHBondContact O-CG 3.43Å; A51-L55 PolarHBondContact O-N 2.73Å; I52-L55 PolarHBondContact O-N 2.97Å; I53-L55 PolarHBondContact O-N 3.19Å; L55-C58 PolarHBondContact O-N 2.87Å; L55-V59 WeakPolarHBondContact O-CG2 3.46Å; L55-V59 PolarHBondContact O-N 2.86Å; L55-V59 VanDerWaalsContact O-N 3.11Å; L55-F143 HydrophobicContact CB-CE2 4.47Å; L55-F143 HydrophobicContact CD2-CD2 3.49Å; L55-F143 VanDerWaalsContact CD2-CD2 3.49Å; L55-F143 HydrophobicContact CD2-CE2 3.6Å; L55-F143 HydrophobicContact CD2-CG 4.06Å; L55-F143 HydrophobicContact CD2-CZ 4.24Å; L55-F143 WeakPolarHBondContact CD2-O 3.47Å; L55-L147 HydrophobicContact CD2-CB 3.92Å; L55-F150 HydrophobicContact CD1-CB 4.24Å; L55-F150 HydrophobicContact CD1-CG 4.36Å
56	V	95.1	Very high	90.2	Very high	95 Å²	95	37.2 Å²	37.2	58%	0.576	22%	0.215	S	C	*	.	H	α-helix	trans	-63.6	-43.9	178.1	173.7	0	0	0	0	111	I52 I53 V59 A60	I52-V56 HydrophobicContact CG2-CG2 4.5Å; I52-V56 WeakPolarHBondContact O-CG2 3.49Å; I52-V56 PolarHBondContact O-N 2.85Å; I53-V56 PolarHBondContact O-N 3.35Å; V56-V59 PolarHBondContact O-N 3.45Å; V56-A60 PolarHBondContact O-N 3.47Å
57	L	93.6	Very high	90.3	Very high	21 Å²	21	37.7 Å²	37.7	11%	0.11	22%	0.222	C	C	.	.	H	α-helix	trans	-63	-43.6	176.2	-70.8	170.2	0	0	0	111.8	I53 T54 V59 A60 I61 F242 L245 V246	I53-L57 HydrophobicContact CG2-CD1 3.81Å; I53-L57 HydrophobicContact CG2-CG 4.35Å; I53-L57 WeakPolarHBondContact O-CB 3.3Å; I53-L57 VanDerWaalsContact O-CG 3.3Å; I53-L57 WeakPolarHBondContact O-CG 3.44Å; I53-L57 PolarHBondContact O-N 3.2Å; T54-L57 PolarHBondContact O-N 3.01Å; L57-V59 VanDerWaalsContact C-N 3.31Å; L57-V59 PolarHBondContact O-N 3Å; L57-A60 PolarHBondContact O-N 3.18Å; L57-I61 VanDerWaalsContact O-CB 3.25Å; L57-I61 WeakPolarHBondContact O-CB 3.39Å; L57-I61 WeakPolarHBondContact O-CD1 3.44Å; L57-I61 WeakPolarHBondContact O-CG1 3.42Å; L57-I61 PolarHBondContact O-N 3.43Å; L57-F242 HydrophobicContact CD2-CB 4.04Å; L57-F242 HydrophobicContact CD2-CD1 3.51Å; L57-F242 HydrophobicContact CD2-CE1 4.1Å; L57-F242 HydrophobicContact CD2-CG 3.85Å; L57-L245 HydrophobicContact CD1-CB 3.91Å; L57-V246 HydrophobicContact CB-CG2 3.48Å; L57-V246 VanDerWaalsContact CB-CG2 3.48Å; L57-V246 HydrophobicContact CD1-CG2 4Å; L57-V246 HydrophobicContact CG-CG2 4.39Å
58	C	93.8	Very high	90.2	Very high	4 Å²	4	37.5 Å²	37.5	3%	0.027	22%	0.221	C	C	.	.	H	α-helix	trans	-58.2	-39.5	175.2	-79.7	0	0	0	0	112.9	T54 L55 F62 A139 F143	T54-C58 WeakPolarHBondContact O-CB 3.36Å; T54-C58 PolarHBondContact O-N 3.21Å; T54-C58 PolarHBondContact O-SG 3.33Å; T54-C58 VanDerWaalsContact O-SG 3.39Å; L55-C58 PolarHBondContact O-N 2.87Å; C58-F62 WeakPolarHBondContact O-CB 3.45Å; C58-F62 PolarHBondContact O-N 3.07Å; C58-A139 PolarHBondContact SG-O 2.93Å; C58-F143 HydrophobicContact CB-CB 3.95Å; C58-F143 HydrophobicContact CB-CD2 4.02Å; C58-F143 HydrophobicContact CB-CG 4.48Å
59	V	93.9	Very high	89.8	Confident	81 Å²	81	38.5 Å²	38.5	49%	0.491	23%	0.227	S	C	.	.	H	α-helix	trans	-69.9	-41.2	175.8	173.8	0	0	0	0	111.5	L55 V56 L57 F62 A63 F143	L55-V59 WeakPolarHBondContact O-CG2 3.46Å; L55-V59 PolarHBondContact O-N 2.86Å; L55-V59 VanDerWaalsContact O-N 3.11Å; V56-V59 PolarHBondContact O-N 3.45Å; L57-V59 VanDerWaalsContact C-N 3.31Å; L57-V59 PolarHBondContact O-N 3Å; V59-F62 PolarHBondContact O-N 3.34Å; V59-A63 PolarHBondContact O-N 3.38Å; V59-F143 HydrophobicContact CG2-CD2 4.13Å; V59-F143 HydrophobicContact CG2-CE2 3.68Å
60	A	93.1	Very high	88.9	Confident	29 Å²	29	37.8 Å²	37.8	24%	0.24	23%	0.23	C	C	.	.	H	α-helix	trans	-65.1	-41.5	176.9	0	0	0	0	0	112	V56 L57 A63 C64 F242	V56-A60 PolarHBondContact O-N 3.47Å; L57-A60 PolarHBondContact O-N 3.18Å; A60-A63 PolarHBondContact O-N 2.6Å; A60-C64 PolarHBondContact O-N 3.16Å; A60-C64 PolarHBondContact O-SG 3.33Å; A60-F242 HydrophobicContact CB-CD2 3.82Å; A60-F242 HydrophobicContact CB-CE2 3.59Å; A60-F242 HydrophobicContact CB-CZ 4.41Å
61	I	92	Very high	88	Confident	0 Å²	0	39.8 Å²	39.8	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-57.7	-48.4	171.5	-75.3	166.9	0	0	0	110.9	L57 A63 C64 V65 M135 A139 F242 V246	L57-I61 VanDerWaalsContact O-CB 3.25Å; L57-I61 WeakPolarHBondContact O-CB 3.39Å; L57-I61 WeakPolarHBondContact O-CD1 3.44Å; L57-I61 WeakPolarHBondContact O-CG1 3.42Å; L57-I61 PolarHBondContact O-N 3.43Å; I61-A63 PolarHBondContact O-N 3.31Å; I61-C64 PolarHBondContact O-N 2.9Å; I61-V65 PolarHBondContact O-N 3.47Å; I61-M135 HydrophobicContact CG2-CE 3.15Å; I61-M135 HydrophobicContact CG2-SD 3.3Å; I61-M135 WeakPolarHBondContact CG2-SD 3.35Å; I61-A139 HydrophobicContact CG2-CB 3.89Å; I61-F242 HydrophobicContact CD1-CB 3.82Å; I61-F242 HydrophobicContact CG1-CB 3.43Å; I61-F242 VanDerWaalsContact CG1-CB 3.43Å; I61-F242 HydrophobicContact CG1-CD2 4.32Å; I61-F242 HydrophobicContact CG1-CG 4.39Å; I61-V246 HydrophobicContact CD1-CG2 3.7Å
62	F	91.1	Very high	86.9	Confident	106 Å²	106	40.4 Å²	40.4	47%	0.465	24%	0.24	S	C	.	.	H	α-helix	trans	-59.3	-46.3	176.7	179.1	-90.5	0	0	0	111.4	C58 V59 C64 V65 A66 I136	C58-F62 WeakPolarHBondContact O-CB 3.45Å; C58-F62 PolarHBondContact O-N 3.07Å; V59-F62 PolarHBondContact O-N 3.34Å; F62-C64 PolarHBondContact O-N 2.76Å; F62-V65 PolarHBondContact O-N 2.84Å; F62-A66 HydrophobicContact CE1-CB 4.28Å; F62-A66 WeakPolarHBondContact O-CB 3.43Å; F62-A66 PolarHBondContact O-N 2.68Å; F62-I136 HydrophobicContact CD2-CG2 4.09Å; F62-I136 HydrophobicContact CE2-CG2 4.09Å
63	A	91.3	Very high	85.6	Confident	57 Å²	57	40.6 Å²	40.6	47%	0.471	25%	0.247	S	C	.	.	H	α-helix	trans	-60.7	-45.8	178.9	0	0	0	0	0	112.7	V59 A60 I61 A66 S67	V59-A63 PolarHBondContact O-N 3.38Å; A60-A63 PolarHBondContact O-N 2.6Å; I61-A63 PolarHBondContact O-N 3.31Å; A63-A66 PolarHBondContact O-N 3.33Å; A63-S67 PolarHBondContact O-N 2.96Å; A63-S67 PolarHBondContact O-OG 3Å
64	C	90.9	Very high	83.7	Confident	23 Å²	23	41.3 Å²	41.3	16%	0.155	25%	0.249	C	C	.	.	H	α-helix	trans	-67	-37	-179.8	-63.9	0	0	0	0	113.1	A60 I61 F62 S67 T68 A239	A60-C64 PolarHBondContact O-N 3.16Å; A60-C64 PolarHBondContact O-SG 3.33Å; I61-C64 PolarHBondContact O-N 2.9Å; F62-C64 PolarHBondContact O-N 2.76Å; C64-S67 PolarHBondContact O-OG 2.79Å; C64-T68 VanDerWaalsContact O-CG2 3.23Å; C64-T68 WeakPolarHBondContact O-CG2 3.21Å; C64-T68 PolarHBondContact O-OG1 2.87Å; C64-A239 HydrophobicContact CB-CB 3.88Å
65	V	88.1	Confident	81.8	Confident	0 Å²	0	42.3 Å²	42.3	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-80	-31.8	176.7	-175.3	0	0	0	0	111.6	I61 F62 T68 L69 K132 M135 I136 Y187 A239	I61-V65 PolarHBondContact O-N 3.47Å; F62-V65 PolarHBondContact O-N 2.84Å; V65-T68 WeakPolarHBondContact CA-OG1 3.47Å; V65-T68 PolarHBondContact O-N 3.33Å; V65-T68 PolarHBondContact O-OG1 2.9Å; V65-L69 WeakPolarHBondContact O-CG 3.14Å; V65-L69 PolarHBondContact O-N 3.22Å; V65-L69 VanDerWaalsContact O-N 3.11Å; V65-K132 HydrophobicContact CG1-CB 3.75Å; V65-K132 HydrophobicContact CG1-CG 3.84Å; V65-M135 HydrophobicContact CB-CE 3.97Å; V65-M135 HydrophobicContact CG1-CE 4.4Å; V65-M135 HydrophobicContact CG2-CE 3.5Å; V65-I136 HydrophobicContact CB-CD1 4.21Å; V65-I136 HydrophobicContact CB-CG1 4.14Å; V65-I136 HydrophobicContact CG1-CD1 3.75Å; V65-I136 HydrophobicContact CG1-CG1 3.91Å; V65-Y187 HydrophobicContact CG2-CE1 4.31Å; V65-Y187 HydrophobicContact CG2-CE2 4.19Å; V65-A239 HydrophobicContact CG2-CB 3.94Å
66	A	86.6	Confident	79.6	Confident	42 Å²	42	47.1 Å²	47.1	35%	0.347	28%	0.28	S	S	.	.	H	α-helix	trans	-67.5	-36.7	175.3	0	0	0	0	0	113.3	F62 A63	F62-A66 HydrophobicContact CE1-CB 4.28Å; F62-A66 WeakPolarHBondContact O-CB 3.43Å; F62-A66 PolarHBondContact O-N 2.68Å; A63-A66 PolarHBondContact O-N 3.33Å
67	S	85.7	Confident	77.3	Confident	48 Å²	48	46.3 Å²	46.3	34%	0.336	28%	0.279	S	S	.	.	H	α-helix	trans	-65.5	-43.3	174.2	52.8	0	0	0	0	112	A63 C64 L69 A70 Q235	A63-S67 PolarHBondContact O-N 2.96Å; A63-S67 PolarHBondContact O-OG 3Å; C64-S67 PolarHBondContact O-OG 2.79Å; S67-L69 VanDerWaalsContact C-N 3.32Å; S67-L69 PolarHBondContact O-N 2.95Å; S67-A70 WeakPolarHBondContact O-CB 3.33Å; S67-A70 PolarHBondContact O-N 3.42Å; S67-Q235 PolarHBondContact OG-OE1 3.06Å
68	T	79.4	Confident	75	Confident	1 Å²	1	50.9 Å²	50.9	1%	0.006	30%	0.303	C	S	.	.	H	α-helix	trans	-73.7	-20.1	-177.7	60.2	0	0	0	0	113.6	C64 V65 A70 K132 Q235 E236	C64-T68 VanDerWaalsContact O-CG2 3.23Å; C64-T68 WeakPolarHBondContact O-CG2 3.21Å; C64-T68 PolarHBondContact O-OG1 2.87Å; V65-T68 WeakPolarHBondContact CA-OG1 3.47Å; V65-T68 PolarHBondContact O-N 3.33Å; V65-T68 PolarHBondContact O-OG1 2.9Å; T68-A70 PolarHBondContact O-N 3.1Å; T68-K132 PolarHBondContact O-NZ 2.99Å; T68-Q235 HydrophobicContact CG2-CB 3.99Å; T68-E236 HydrophobicContact CG2-CG 3.5Å; T68-E236 VanDerWaalsContact CG2-CG 3.5Å
69	L	76.3	Confident	72.6	Confident	53 Å²	53	59.1 Å²	59.1	28%	0.277	34%	0.339	S	S	.	.	H	α-helix	trans	-66.8	-19.6	172.8	-85.5	172.5	0	0	0	113.8	V65 S67 Y71 D72 S73 K132 I136	V65-L69 WeakPolarHBondContact O-CG 3.14Å; V65-L69 PolarHBondContact O-N 3.22Å; V65-L69 VanDerWaalsContact O-N 3.11Å; S67-L69 VanDerWaalsContact C-N 3.32Å; S67-L69 PolarHBondContact O-N 2.95Å; L69-Y71 VanDerWaalsContact C-N 3.32Å; L69-Y71 PolarHBondContact O-N 3.05Å; L69-D72 PolarHBondContact O-N 2.87Å; L69-S73 PolarHBondContact O-N 2.91Å; L69-S73 VanDerWaalsContact O-N 3.17Å; L69-K132 HydrophobicContact CD2-CB 3.93Å; L69-K132 HydrophobicContact CD2-CD 4Å; L69-K132 HydrophobicContact CG-CB 4.4Å; L69-K132 HydrophobicContact CG-CD 4.36Å; L69-I136 HydrophobicContact CD1-CD1 3.59Å
70	A	68.9	Low	70.1	Confident	45 Å²	45	58.6 Å²	58.6	37%	0.372	35%	0.35	S	S	.	.	H	α-helix	trans	-60.1	-43.7	177.9	0	0	0	0	0	111.4	S67 T68 S73 Q74	S67-A70 WeakPolarHBondContact O-CB 3.33Å; S67-A70 PolarHBondContact O-N 3.42Å; T68-A70 PolarHBondContact O-N 3.1Å; A70-S73 WeakPolarHBondContact O-CB 3.4Å; A70-S73 PolarHBondContact O-N 2.92Å; A70-S73 VanDerWaalsContact O-N 3.16Å; A70-S73 PolarHBondContact O-OG 3.34Å; A70-Q74 PolarHBondContact O-N 2.94Å
71	Y	68.8	Low	67.5	Low	69 Å²	69	60.2 Å²	60.2	27%	0.271	37%	0.37	S	S	.	.	H	α-helix	trans	-69.6	-35.1	-179.2	-53.1	-58	0	0	0	112.5	L69 S73 Q74 A75 H228	L69-Y71 VanDerWaalsContact C-N 3.32Å; L69-Y71 PolarHBondContact O-N 3.05Å; Y71-S73 PolarHBondContact O-N 3.37Å; Y71-Q74 PolarHBondContact O-N 2.98Å; Y71-A75 PolarHBondContact O-N 3.21Å; Y71-H228 AromaticContact CD1-CD2 3.87Å; Y71-H228 AromaticContact CD1-CE1 3.93Å; Y71-H228 AromaticContact CD1-NE2 3.47Å; Y71-H228 WeakPolarHBondContact CD1-NE2 3.37Å; Y71-H228 AromaticContact CD2-CE1 3.81Å; Y71-H228 AromaticContact CD2-ND1 3.79Å; Y71-H228 AromaticContact CE1-CE1 3.73Å; Y71-H228 AromaticContact CE1-NE2 3.56Å; Y71-H228 AromaticContact CE2-CE1 3.59Å; Y71-H228 AromaticContact CE2-ND1 3.84Å; Y71-H228 AromaticContact CG-CD2 3.73Å; Y71-H228 AromaticContact CG-CE1 3.97Å; Y71-H228 AromaticContact CG-NE2 3.73Å; Y71-H228 AromaticContact CZ-CE1 3.54Å; Y71-H228 AromaticContact CZ-NE2 3.89Å
72	D	66.3	Low	65.1	Low	14 Å²	14	65.5 Å²	65.5	8%	0.075	40%	0.402	C	S	.	.	H	α-helix	trans	-66.7	-25.3	172.7	-54.7	-50.8	0	0	0	112.6	L69 K132	L69-D72 PolarHBondContact O-N 2.87Å; D72-K132 IonicContact OD1-NZ 2.71Å; D72-K132 PolarHBondContact OD1-NZ 3.34Å; D72-K132 WeakPolarHBondContact OD2-CD 3.29Å; D72-K132 WeakPolarHBondContact OD2-CE 3.3Å; D72-K132 IonicContact OD2-NZ 2.73Å; D72-K132 PolarHBondContact OD2-NZ 3.2Å
73	S	62.7	Low	62.6	Low	65 Å²	65	71.5 Å²	71.5	46%	0.455	42%	0.423	S	S	.	.	H	α-helix	trans	-75.8	-39.7	175.4	80.8	0	0	0	0	112.2	L69 A70 Y71 A75 M76	L69-S73 PolarHBondContact O-N 2.91Å; L69-S73 VanDerWaalsContact O-N 3.17Å; A70-S73 WeakPolarHBondContact O-CB 3.4Å; A70-S73 PolarHBondContact O-N 2.92Å; A70-S73 VanDerWaalsContact O-N 3.16Å; A70-S73 PolarHBondContact O-OG 3.34Å; Y71-S73 PolarHBondContact O-N 3.37Å; S73-A75 VanDerWaalsContact C-N 3.28Å; S73-A75 PolarHBondContact O-N 2.86Å; S73-M76 PolarHBondContact O-N 2.69Å
74	Q	53.5	Low	60	Low	90 Å²	90	72.2 Å²	72.2	42%	0.421	44%	0.436	S	S	.	.	H	α-helix	trans	-70.3	-23.5	179.6	-69.1	175.6	-15	0	0	113.1	A70 Y71 M76 S77 N78	A70-Q74 PolarHBondContact O-N 2.94Å; Y71-Q74 PolarHBondContact O-N 2.98Å; Q74-M76 VanDerWaalsContact C-N 3.31Å; Q74-M76 PolarHBondContact O-N 3Å; Q74-S77 WeakPolarHBondContact CA-OG 3.39Å; Q74-S77 PolarHBondContact O-N 3.48Å; Q74-S77 PolarHBondContact O-OG 2.96Å; Q74-N78 PolarHBondContact O-N 3.32Å
75	A	53.6	Low	57.3	Low	21 Å²	21	74.9 Å²	74.9	17%	0.174	47%	0.467	C	S	.	.	H	α-helix	trans	-51.6	-49.6	172.3	0	0	0	0	0	111.9	Y71 S73 F79 Y225	Y71-A75 PolarHBondContact O-N 3.21Å; S73-A75 VanDerWaalsContact C-N 3.28Å; S73-A75 PolarHBondContact O-N 2.86Å; A75-F79 VanDerWaalsContact O-CB 3.25Å; A75-F79 WeakPolarHBondContact O-CB 3.39Å; A75-F79 PolarHBondContact O-N 3.29Å; A75-Y225 HydrophobicContact CB-CD1 3.91Å; A75-Y225 HydrophobicContact CB-CD2 3.48Å; A75-Y225 VanDerWaalsContact CB-CD2 3.48Å; A75-Y225 HydrophobicContact CB-CE1 4.26Å; A75-Y225 HydrophobicContact CB-CE2 3.85Å; A75-Y225 HydrophobicContact CB-CG 3.48Å; A75-Y225 VanDerWaalsContact CB-CG 3.48Å
76	M	46.3	Very low	55	Low	126 Å²	126	81.5 Å²	81.5	62%	0.621	51%	0.514	S	S	*	.	H	α-helix	trans	-74.1	-33.3	-175.9	-162.4	176.8	-171.6	0	0	112.8	S73 Q74 G80	S73-M76 PolarHBondContact O-N 2.69Å; Q74-M76 VanDerWaalsContact C-N 3.31Å; Q74-M76 PolarHBondContact O-N 3Å; M76-G80 PolarHBondContact O-N 3.43Å; M76-G80 VanDerWaalsContact O-N 3.12Å
77	S	47.7	Very low	52.4	Low	77 Å²	77	83.2 Å²	83.2	54%	0.538	54%	0.535	S	S	.	.	H	α-helix	trans	-68.1	-37.3	178.4	58	0	0	0	0	112.6	Q74	Q74-S77 WeakPolarHBondContact CA-OG 3.39Å; Q74-S77 PolarHBondContact O-N 3.48Å; Q74-S77 PolarHBondContact O-OG 2.96Å
78	N	45.1	Very low	50	Low	117 Å²	117	84.6 Å²	84.6	63%	0.626	56%	0.557	S	S	*	*	H	α-helix	trans	-81.5	-41.4	177.3	-76.6	24.6	0	0	0	112	Q74 G80 G81 T82	Q74-N78 PolarHBondContact O-N 3.32Å; N78-G80 VanDerWaalsContact C-N 3.26Å; N78-G80 PolarHBondContact O-N 3.41Å; N78-G81 PolarHBondContact O-N 3.03Å; N78-T82 PolarHBondContact O-OG1 3.24Å
79	F	43.2	Very low	47.7	Very low	177 Å²	177	92.5 Å²	92.5	78%	0.776	60%	0.596	S	S	*	*	H	α-helix	trans	-67.3	-27.9	-178.6	-144.7	-94	0	0	0	112.9	A75 G81	A75-F79 VanDerWaalsContact O-CB 3.25Å; A75-F79 WeakPolarHBondContact O-CB 3.39Å; A75-F79 PolarHBondContact O-N 3.29Å; F79-G81 VanDerWaalsContact C-N 3.29Å; F79-G81 PolarHBondContact O-N 2.98Å
80	G	40.5	Very low	45.6	Very low	71 Å²	71	100.3 Å²	100.3	73%	0.732	62%	0.624	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.7	-10	171.1	0	0	0	0	0	115.3	M76 N78	M76-G80 PolarHBondContact O-N 3.43Å; M76-G80 VanDerWaalsContact O-N 3.12Å; N78-G80 VanDerWaalsContact C-N 3.26Å; N78-G80 PolarHBondContact O-N 3.41Å
81	G	40.3	Very low	44.2	Very low	63 Å²	63	102.1 Å²	102.1	65%	0.649	65%	0.646	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.6	-8.3	-170.5	0	0	0	0	0	116.6	N78 F79	N78-G81 PolarHBondContact O-N 3.03Å; F79-G81 VanDerWaalsContact C-N 3.29Å; F79-G81 PolarHBondContact O-N 2.98Å
82	T	40.9	Very low	42.5	Very low	110 Å²	110	102.8 Å²	102.8	68%	0.675	67%	0.674	S	S	*	*	S	Bend	trans	-114.2	-11	-165.6	-46.6	0	0	0	0	115.2	N78	N78-T82 PolarHBondContact O-OG1 3.24Å
83	Y	38.1	Very low	40.9	Very low	232 Å²	232	108.4 Å²	108.4	91%	0.91	72%	0.715	S	S	*	*	S	Bend	trans	-126.1	47.7	-178.6	-89.7	-84.5	0	0	0	113.3
84	G	36.9	Very low	39.4	Very low	72 Å²	72	108.9 Å²	108.9	74%	0.742	73%	0.73	S	S	*	*	S	Bend	trans	-150.6	82.4	-176.7	0	0	0	0	0	115.4
85	G	34.2	Very low	38.4	Very low	79 Å²	79	108.1 Å²	108.1	81%	0.814	75%	0.746	S	S	*	*			trans	87.2	125.4	157.2	0	0	0	0	0	117.4	G87	G85-G87 PolarHBondContact O-N 2.87Å
86	S	40	Very low	37.2	Very low	139 Å²	139	115.1 Å²	115.1	97%	0.972	78%	0.777	S	S	*	*	S	Bend	trans	-77.7	112.2	161.5	154.9	0	0	0	0	110
87	G	33.1	Very low	36.4	Very low	78 Å²	78	119.7 Å²	119.7	80%	0.804	79%	0.789	S	S	*	*			trans	153.5	151.7	165.8	0	0	0	0	0	114	G85	G85-G87 PolarHBondContact O-N 2.87Å
88	G	33.3	Very low	35.6	Very low	77 Å²	77	119.7 Å²	119.7	79%	0.794	80%	0.801	S	S	*	*			trans	116	38.1	168.3	0	0	0	0	0	117.8
89	M	31.9	Very low	35	Very low	167 Å²	167	118 Å²	118	82%	0.823	81%	0.812	S	S	*	*			trans	-67.4	151.5	154	-173.1	70	124.4	0	0	109.1
90	Y	31.8	Very low	34.4	Very low	218 Å²	218	116 Å²	116	86%	0.855	82%	0.82	S	S	*	*	S	Bend	trans	77.3	130.5	-176.9	-65.6	-89.5	0	0	0	116.8
91	G	39.8	Very low	33.9	Very low	82 Å²	82	116.2 Å²	116.2	85%	0.845	82%	0.822	S	S	*	*			trans	-83.8	154.1	166.4	0	0	0	0	0	111.9
92	G	32.8	Very low	33.4	Very low	83 Å²	83	117 Å²	117	86%	0.856	83%	0.83	S	S	*	*			trans	-140.6	140.8	178	0	0	0	0	0	111.4
93	S	33.8	Very low	33.1	Very low	133 Å²	133	120.5 Å²	120.5	93%	0.93	84%	0.841	S	S	*	*			trans	-92.3	142.3	177.5	177.8	0	0	0	0	111.5
94	G	31.6	Very low	32.7	Very low	75 Å²	75	120.5 Å²	120.5	77%	0.773	84%	0.841	S	S	*	*			trans	124.8	156.5	152.2	0	0	0	0	0	117
95	G	30.9	Very low	32.9	Very low	74 Å²	74	120.9 Å²	120.9	76%	0.763	85%	0.845	S	S	*	*			trans	102.7	60	146.5	0	0	0	0	0	119.3
96	M	28.4	Very low	32.7	Very low	168 Å²	168	120.9 Å²	120.9	83%	0.828	84%	0.844	S	S	*	*				13.4	118.4	125.1	-175.4	82.4	126.4	0	0	117.7
97	Y	29.8	Very low	32.2	Very low	221 Å²	221	120.1 Å²	120.1	87%	0.867	84%	0.839	S	S	*	*				-176.4	140.2	117.4	-117.9	-87.8	0	0	0	114.7
98	G	31.9	Very low	32.5	Very low	77 Å²	77	122 Å²	122	79%	0.794	84%	0.84	S	S	*	*			trans	68.2	100.9	146.1	0	0	0	0	0	120.5
99	G	32.4	Very low	32.3	Very low	82 Å²	82	129.3 Å²	129.3	85%	0.845	85%	0.846	S	S	*	*			trans	179.4	52.3	171.1	0	0	0	0	0	115.8
100	S	29.2	Very low	32.6	Very low	135 Å²	135	133.2 Å²	133.2	94%	0.944	85%	0.853	S	S	*	*			trans	-68.9	129.2	-177.1	-173.6	0	0	0	0	112.7
101	G	31.2	Very low	32.5	Very low	75 Å²	75	126.1 Å²	126.1	77%	0.773	85%	0.846	S	S	*	*			trans	-174.7	59	-175.5	0	0	0	0	0	118
102	G	30.4	Very low	32.4	Very low	80 Å²	80	127.1 Å²	127.1	83%	0.825	85%	0.846	S	S	*	*			trans	67.9	94.2	151.5	0	0	0	0	0	119.3
103	M	34.1	Very low	32.4	Very low	183 Å²	183	126.4 Å²	126.4	90%	0.901	84%	0.839	S	S	*	*			trans	-75.7	119.3	163.9	174.4	82.7	138.7	0	0	111
104	Y	29.7	Very low	32.7	Very low	233 Å²	233	125.8 Å²	125.8	91%	0.914	83%	0.83	S	S	*	*			trans	-151.5	133.5	153.7	-105.6	-77.2	0	0	0	110.4
105	G	39.6	Very low	32.7	Very low	80 Å²	80	128.4 Å²	128.4	83%	0.825	83%	0.826	S	S	*	*			trans	-81.9	145	-178.3	0	0	0	0	0	113.3
106	G	30	Very low	32.8	Very low	78 Å²	78	135.4 Å²	135.4	80%	0.804	83%	0.831	S	S	*	*			trans	-143.8	138	174.2	0	0	0	0	0	110.9
107	S	30	Very low	32.9	Very low	123 Å²	123	130 Å²	130	86%	0.86	82%	0.818	S	S	*	*			trans	-71.3	157.7	-176	-76.5	0	0	0	0	113.7	Y109	S107-Y109 PolarHBondContact O-N 3.15Å
108	S	40.1	Very low	33.2	Very low	119 Å²	119	131.6 Å²	131.6	83%	0.832	82%	0.824	S	S	*	*			trans	-42.5	123	172.9	-49.9	0	0	0	0	114.1
109	Y	29.5	Very low	33.5	Very low	230 Å²	230	131.1 Å²	131.1	90%	0.902	82%	0.819	S	S	*	*			trans	-144.1	146.8	153.1	-113.1	-84.9	0	0	0	110	S107 G111	S107-Y109 PolarHBondContact O-N 3.15Å; Y109-G111 PolarHBondContact O-N 2.91Å
110	Y	37.3	Very low	33.8	Very low	249 Å²	249	133 Å²	133	98%	0.976	82%	0.819	S	S	*	*			trans	-66	104	173.9	-97.8	-112.2	0	0	0	109.7
111	G	29.8	Very low	34.4	Very low	68 Å²	68	132.3 Å²	132.3	70%	0.701	80%	0.804	S	S	*	*			trans	-114.3	141.9	174.1	0	0	0	0	0	111.4	Y109 G113	Y109-G111 PolarHBondContact O-N 2.91Å; G111-G113 PolarHBondContact O-N 3.02Å
112	A	38	Very low	34.9	Very low	103 Å²	103	131.9 Å²	131.9	85%	0.851	80%	0.8	S	S	*	*			trans	-71.2	96.9	-178.9	0	0	0	0	0	111.5	T114	A112-T114 PolarHBondContact O-N 2.98Å
113	G	32.5	Very low	35.9	Very low	69 Å²	69	131.4 Å²	131.4	71%	0.711	80%	0.795	S	S	*	*			trans	-76.1	98.3	175.3	0	0	0	0	0	112.1	G111 N115	G111-G113 PolarHBondContact O-N 3.02Å; G113-N115 VanDerWaalsContact C-N 3.31Å; G113-N115 PolarHBondContact O-N 3.39Å
114	T	39.4	Very low	36.9	Very low	119 Å²	119	127.5 Å²	127.5	73%	0.73	78%	0.777	S	S	*	*			trans	-66.8	82.6	175	-51.8	0	0	0	0	111.3	A112 Y116	A112-T114 PolarHBondContact O-N 2.98Å; T114-Y116 HydrophobicContact CG2-CD2 4.14Å; T114-Y116 HydrophobicContact CG2-CE2 3.8Å
115	N	31.7	Very low	38.5	Very low	130 Å²	130	120 Å²	120	70%	0.695	75%	0.748	S	S	*	*			trans	-92.6	108	-177.6	-163	4.3	0	0	0	111.4	G113 G117	G113-N115 VanDerWaalsContact C-N 3.31Å; G113-N115 PolarHBondContact O-N 3.39Å; N115-G117 VanDerWaalsContact C-N 3.29Å; N115-G117 PolarHBondContact O-N 3.06Å
116	Y	33.3	Very low	39.8	Very low	222 Å²	222	119.5 Å²	119.5	87%	0.871	73%	0.726	S	S	*	*			trans	-76	75.3	178.3	-87.1	-96	0	0	0	111.4	T114	T114-Y116 HydrophobicContact CG2-CD2 4.14Å; T114-Y116 HydrophobicContact CG2-CE2 3.8Å
117	G	31.4	Very low	41.9	Very low	54 Å²	54	120.1 Å²	120.1	56%	0.557	71%	0.711	S	S	*	*	S	Bend	trans	-145.3	89.7	179.1	0	0	0	0	0	113.1	N115 G119	N115-G117 VanDerWaalsContact C-N 3.29Å; N115-G117 PolarHBondContact O-N 3.06Å; G117-G119 PolarHBondContact O-N 3.43Å
118	Y	35	Very low	44.2	Very low	255 Å²	255	114.4 Å²	114.4	100%	1	67%	0.671	S	S	*	*	S	Bend	trans	44.4	24.4	159.5	-116	-84.8	0	0	0	119.7
119	G	39.1	Very low	46.1	Very low	66 Å²	66	116 Å²	116	68%	0.68	66%	0.659	S	S	*	*			trans	-118.2	-9.8	177.6	0	0	0	0	0	115.9	G117 I121	G117-G119 PolarHBondContact O-N 3.43Å; G119-I121 PolarHBondContact O-N 3.14Å
120	S	39	Very low	48.6	Very low	122 Å²	122	108.4 Å²	108.4	85%	0.853	64%	0.639	S	S	*	*			trans	-85.9	69.2	-174.2	-163.6	0	0	0	0	112.8	G122	S120-G122 PolarHBondContact O-N 3.38Å
121	I	40.8	Very low	50.9	Low	121 Å²	121	96.6 Å²	96.6	62%	0.621	59%	0.593	S	S	*	*			trans	-82.2	103.9	158.8	-66.7	-178.2	0	0	0	106.9	G119 G123 Y201	G119-I121 PolarHBondContact O-N 3.14Å; I121-G123 PolarHBondContact O-N 3.07Å; I121-Y201 HydrophobicContact CG2-CE1 4.23Å; I121-Y201 HydrophobicContact CG2-CE2 4.14Å; I121-Y201 VanDerWaalsContact CG2-OH 3.24Å; I121-Y201 WeakPolarHBondContact CG2-OH 3.07Å
122	G	41.5	Very low	53.6	Low	66 Å²	66	93.7 Å²	93.7	68%	0.68	56%	0.561	S	S	*	*			trans	-67.2	118.1	-170.6	0	0	0	0	0	114.1	S120	S120-G122 PolarHBondContact O-N 3.38Å
123	G	52.8	Low	55.9	Low	70 Å²	70	90.5 Å²	90.5	72%	0.722	54%	0.538	S	S	*	.	S	Bend	trans	75.9	55.6	144.9	0	0	0	0	0	118.3	I121	I121-G123 PolarHBondContact O-N 3.07Å
124	N	55.4	Low	58.6	Low	101 Å²	101	90.6 Å²	90.6	54%	0.54	52%	0.519	S	S	.	.	S	Bend	trans	-166.4	19.2	147.6	-111.9	-28	0	0	0	116
125	Y	61.4	Low	61	Low	75 Å²	75	85 Å²	85	29%	0.294	49%	0.485	S	S	.	.			trans	-124.8	142	-177.5	175.2	-115.2	0	0	0	110.8	D127 Q196 I205 Y229	Y125-D127 WeakPolarHBondContact CE1-OD1 3.39Å; Y125-Q196 VanDerWaalsContact CD2-OE1 3.23Å; Y125-I205 HydrophobicContact CD2-CD1 3.7Å; Y125-I205 HydrophobicContact CE2-CD1 3.44Å; Y125-I205 VanDerWaalsContact CE2-CD1 3.44Å; Y125-Y229 WeakPolarHBondContact OH-CE1 3.43Å; Y125-Y229 VanDerWaalsContact OH-CZ 3.26Å; Y125-Y229 PolarHBondContact OH-OH 3.13Å
126	N	67.4	Low	63.8	Low	69 Å²	69	80.3 Å²	80.3	37%	0.369	46%	0.459	S	S	.	.			trans	-98.6	103.2	178.4	-74.8	-24.3	0	0	0	110.2	V189 Q196	N126-V189 WeakPolarHBondContact ND2-CG1 3.27Å; N126-Q196 PolarHBondContact O-NE2 2.76Å
127	D	75	Confident	66.6	Low	91 Å²	91	71.5 Å²	71.5	49%	0.487	43%	0.432	S	S	.	.			trans	-61.5	128.8	175.9	-68.8	-44.5	0	0	0	111.6	Y125 R129 S130 G131	Y125-D127 WeakPolarHBondContact CE1-OD1 3.39Å; D127-R129 PolarHBondContact O-N 2.8Å; D127-S130 PolarHBondContact O-N 3.45Å; D127-S130 PolarHBondContact O-OG 2.89Å; D127-G131 PolarHBondContact O-N 3.01Å; D127-G131 VanDerWaalsContact O-N 3.16Å
128	P	76.9	Confident	69.4	Low	3 Å²	3	70.3 Å²	70.3	2%	0.019	41%	0.413	C	S	.	.	H	α-helix	trans	-54.6	-40.3	179.5	18.2	-30.5	0	0	0	112.4	S130 G131 K132 Y225 Y229	P128-S130 VanDerWaalsContact C-N 3.34Å; P128-S130 PolarHBondContact O-N 3.42Å; P128-G131 PolarHBondContact O-N 3.47Å; P128-K132 WeakPolarHBondContact O-CB 3.45Å; P128-K132 WeakPolarHBondContact O-CG 3.44Å; P128-K132 PolarHBondContact O-N 2.93Å; P128-Y225 WeakPolarHBondContact CG-OH 3.13Å; P128-Y229 HydrophobicContact CB-CD2 4.02Å; P128-Y229 HydrophobicContact CB-CE2 3.83Å; P128-Y229 HydrophobicContact CG-CD2 3.84Å; P128-Y229 HydrophobicContact CG-CE2 3.68Å
129	R	80.8	Confident	72.1	Confident	154 Å²	154	58.3 Å²	58.3	58%	0.581	37%	0.366	S	S	*	.	H	α-helix	trans	-63.5	-34.4	178.6	-173.3	173.1	178.9	151.7	-1.5	113.3	D127 G133	D127-R129 PolarHBondContact O-N 2.8Å; R129-G133 PolarHBondContact O-N 3.47Å; R129-G133 VanDerWaalsContact O-N 3.1Å
130	S	82.4	Confident	74.7	Confident	69 Å²	69	58 Å²	58	48%	0.483	35%	0.351	S	S	.	.	H	α-helix	trans	-76.3	-40.3	177.7	75.5	0	0	0	0	111.1	D127 P128 G133 F134	D127-S130 PolarHBondContact O-N 3.45Å; D127-S130 PolarHBondContact O-OG 2.89Å; P128-S130 VanDerWaalsContact C-N 3.34Å; P128-S130 PolarHBondContact O-N 3.42Å; S130-G133 PolarHBondContact O-N 3.45Å; S130-F134 WeakPolarHBondContact O-CB 3.4Å; S130-F134 PolarHBondContact O-N 2.71Å
131	G	84.3	Confident	77.2	Confident	1 Å²	1	57.9 Å²	57.9	1%	0.01	34%	0.336	C	S	.	.	H	α-helix	trans	-60.2	-46.9	172.3	0	0	0	0	0	112.9	D127 P128 G133 F134 M135	D127-G131 PolarHBondContact O-N 3.01Å; D127-G131 VanDerWaalsContact O-N 3.16Å; P128-G131 PolarHBondContact O-N 3.47Å; G131-G133 PolarHBondContact O-N 2.92Å; G131-F134 PolarHBondContact O-N 3.49Å; G131-M135 WeakPolarHBondContact O-CB 3.34Å; G131-M135 PolarHBondContact O-N 2.85Å
132	K	86.6	Confident	79.8	Confident	8 Å²	8	52.2 Å²	52.2	4%	0.035	31%	0.306	C	S	.	.	H	α-helix	trans	-58.9	-45.3	174.3	-75.8	172.6	174	178.6	0	112.2	V65 T68 L69 D72 P128 M135 I136 Y187 E236	V65-K132 HydrophobicContact CG1-CB 3.75Å; V65-K132 HydrophobicContact CG1-CG 3.84Å; T68-K132 PolarHBondContact O-NZ 2.99Å; L69-K132 HydrophobicContact CD2-CB 3.93Å; L69-K132 HydrophobicContact CD2-CD 4Å; L69-K132 HydrophobicContact CG-CB 4.4Å; L69-K132 HydrophobicContact CG-CD 4.36Å; D72-K132 IonicContact OD1-NZ 2.71Å; D72-K132 PolarHBondContact OD1-NZ 3.34Å; D72-K132 WeakPolarHBondContact OD2-CD 3.29Å; D72-K132 WeakPolarHBondContact OD2-CE 3.3Å; D72-K132 IonicContact OD2-NZ 2.73Å; D72-K132 PolarHBondContact OD2-NZ 3.2Å; P128-K132 WeakPolarHBondContact O-CB 3.45Å; P128-K132 WeakPolarHBondContact O-CG 3.44Å; P128-K132 PolarHBondContact O-N 2.93Å; K132-M135 PolarHBondContact O-N 3.26Å; K132-I136 WeakPolarHBondContact O-CG1 3.47Å; K132-I136 PolarHBondContact O-N 3.21Å; K132-Y187 HydrophobicContact CG-CD2 4.27Å; K132-Y187 HydrophobicContact CG-CE2 3.76Å; K132-E236 WeakPolarHBondContact CE-OE1 3.49Å; K132-E236 IonicContact NZ-OE1 3.41Å; K132-E236 PolarHBondContact NZ-OE1 2.78Å
133	G	86.3	Confident	82.3	Confident	35 Å²	35	52.3 Å²	52.3	36%	0.361	29%	0.288	S	S	.	.	H	α-helix	trans	-63.7	-42.5	176	0	0	0	0	0	113.6	R129 S130 G131 I136 A137	R129-G133 PolarHBondContact O-N 3.47Å; R129-G133 VanDerWaalsContact O-N 3.1Å; S130-G133 PolarHBondContact O-N 3.45Å; G131-G133 PolarHBondContact O-N 2.92Å; G133-I136 PolarHBondContact O-N 3.3Å; G133-A137 PolarHBondContact O-N 2.75Å
134	F	89.8	Confident	84.3	Confident	71 Å²	71	53.3 Å²	53.3	31%	0.311	28%	0.276	S	S	.	.	H	α-helix	trans	-64	-42.7	177.4	-177	-118.3	0	0	0	112.1	S130 G131 A137 M138 I182 A183 V186	S130-F134 WeakPolarHBondContact O-CB 3.4Å; S130-F134 PolarHBondContact O-N 2.71Å; G131-F134 PolarHBondContact O-N 3.49Å; F134-A137 PolarHBondContact O-N 2.71Å; F134-M138 HydrophobicContact CD2-CE 4.35Å; F134-M138 HydrophobicContact CE2-CE 3.51Å; F134-M138 HydrophobicContact CE2-CG 4.21Å; F134-M138 HydrophobicContact CZ-CE 3.97Å; F134-M138 HydrophobicContact CZ-CG 4.25Å; F134-M138 PolarHBondContact O-N 2.9Å; F134-M138 VanDerWaalsContact O-N 3.07Å; F134-I182 HydrophobicContact CE1-CG2 4.37Å; F134-A183 HydrophobicContact CD1-CB 3.99Å; F134-A183 HydrophobicContact CE1-CB 3.78Å; F134-V186 HydrophobicContact CD1-CB 4.26Å; F134-V186 HydrophobicContact CD1-CG1 4.05Å; F134-V186 HydrophobicContact CE1-CB 4.44Å; F134-V186 HydrophobicContact CE1-CG2 4.48Å
135	M	89.9	Confident	86	Confident	2 Å²	2	50 Å²	50	1%	0.01	26%	0.257	C	S	.	.	H	α-helix	trans	-57.4	-52.6	173.3	-161.2	-50	-58.3	0	0	110.4	I61 V65 G131 K132 A137 M138 A139 Y187	I61-M135 HydrophobicContact CG2-CE 3.15Å; I61-M135 HydrophobicContact CG2-SD 3.3Å; I61-M135 WeakPolarHBondContact CG2-SD 3.35Å; V65-M135 HydrophobicContact CB-CE 3.97Å; V65-M135 HydrophobicContact CG1-CE 4.4Å; V65-M135 HydrophobicContact CG2-CE 3.5Å; G131-M135 WeakPolarHBondContact O-CB 3.34Å; G131-M135 PolarHBondContact O-N 2.85Å; K132-M135 PolarHBondContact O-N 3.26Å; M135-A137 VanDerWaalsContact C-N 3.32Å; M135-A137 PolarHBondContact O-N 3.14Å; M135-M138 PolarHBondContact O-N 3.34Å; M135-A139 HydrophobicContact CE-CB 4.22Å; M135-A139 WeakPolarHBondContact O-CB 3.44Å; M135-A139 PolarHBondContact O-N 2.71Å; M135-A139 HydrophobicContact SD-CB 4.12Å; M135-Y187 HydrophobicContact CB-CD2 4.23Å; M135-Y187 HydrophobicContact CB-CG 4.14Å; M135-Y187 HydrophobicContact CG-CD1 3.99Å; M135-Y187 HydrophobicContact CG-CD2 4.25Å; M135-Y187 HydrophobicContact CG-CG 3.77Å
136	I	90.2	Very high	87.4	Confident	31 Å²	31	46.4 Å²	46.4	16%	0.159	24%	0.243	C	C	.	.	H	α-helix	trans	-58.1	-42.6	179.2	-74.1	169.5	0	0	0	111.8	F62 V65 L69 K132 G133 T140	F62-I136 HydrophobicContact CD2-CG2 4.09Å; F62-I136 HydrophobicContact CE2-CG2 4.09Å; V65-I136 HydrophobicContact CB-CD1 4.21Å; V65-I136 HydrophobicContact CB-CG1 4.14Å; V65-I136 HydrophobicContact CG1-CD1 3.75Å; V65-I136 HydrophobicContact CG1-CG1 3.91Å; L69-I136 HydrophobicContact CD1-CD1 3.59Å; K132-I136 WeakPolarHBondContact O-CG1 3.47Å; K132-I136 PolarHBondContact O-N 3.21Å; G133-I136 PolarHBondContact O-N 3.3Å; I136-T140 WeakPolarHBondContact O-CB 3.25Å; I136-T140 PolarHBondContact O-N 3.37Å; I136-T140 PolarHBondContact O-OG1 3.32Å
137	A	91.9	Very high	88.6	Confident	37 Å²	37	46.2 Å²	46.2	31%	0.306	24%	0.242	S	C	.	.	H	α-helix	trans	-61.1	-47.8	178.2	0	0	0	0	0	111.9	G133 F134 M135 T140 F141	G133-A137 PolarHBondContact O-N 2.75Å; F134-A137 PolarHBondContact O-N 2.71Å; M135-A137 VanDerWaalsContact C-N 3.32Å; M135-A137 PolarHBondContact O-N 3.14Å; A137-T140 WeakPolarHBondContact O-CB 3.35Å; A137-T140 PolarHBondContact O-N 2.73Å; A137-F141 WeakPolarHBondContact O-CD2 3.46Å; A137-F141 PolarHBondContact O-N 3.37Å
138	M	91.1	Very high	89.3	Confident	29 Å²	29	45.4 Å²	45.4	14%	0.143	24%	0.24	C	C	.	.	H	α-helix	trans	-69.1	-39.9	-179.7	-67.6	-61.1	166.7	0	0	112.5	F134 M135 T140 F141 V142 L179 M180 A183	F134-M138 HydrophobicContact CD2-CE 4.35Å; F134-M138 HydrophobicContact CE2-CE 3.51Å; F134-M138 HydrophobicContact CE2-CG 4.21Å; F134-M138 HydrophobicContact CZ-CE 3.97Å; F134-M138 HydrophobicContact CZ-CG 4.25Å; F134-M138 PolarHBondContact O-N 2.9Å; F134-M138 VanDerWaalsContact O-N 3.07Å; M135-M138 PolarHBondContact O-N 3.34Å; M138-T140 PolarHBondContact O-N 3.48Å; M138-F141 PolarHBondContact O-N 3.15Å; M138-F141 HydrophobicContact SD-CD2 4.16Å; M138-V142 PolarHBondContact O-N 3.42Å; M138-L179 HydrophobicContact SD-CB 4.1Å; M138-L179 HydrophobicContact SD-CD1 4.43Å; M138-M180 VanDerWaalsContact C-SD 3.56Å; M138-M180 HydrophobicContact CB-SD 3.77Å; M138-A183 HydrophobicContact CB-CB 3.9Å; M138-A183 HydrophobicContact CG-CB 3.96Å
139	A	91.8	Very high	89.8	Confident	3 Å²	3	45.7 Å²	45.7	3%	0.025	24%	0.241	C	C	.	.	H	α-helix	trans	-59.2	-36.3	171.6	0	0	0	0	0	112	C58 I61 M135 F143	C58-A139 PolarHBondContact SG-O 2.93Å; I61-A139 HydrophobicContact CG2-CB 3.89Å; M135-A139 HydrophobicContact CE-CB 4.22Å; M135-A139 WeakPolarHBondContact O-CB 3.44Å; M135-A139 PolarHBondContact O-N 2.71Å; M135-A139 HydrophobicContact SD-CB 4.12Å; A139-F143 VanDerWaalsContact O-CB 3.31Å; A139-F143 WeakPolarHBondContact O-CB 3.45Å; A139-F143 PolarHBondContact O-N 2.9Å
140	T	92.6	Very high	90.2	Very high	59 Å²	59	41.2 Å²	41.2	36%	0.362	23%	0.226	S	C	.	.	H	α-helix	trans	-69	-43.7	176.1	-56.7	0	0	0	0	112	I136 A137 M138 V142 F143 I144	I136-T140 WeakPolarHBondContact O-CB 3.25Å; I136-T140 PolarHBondContact O-N 3.37Å; I136-T140 PolarHBondContact O-OG1 3.32Å; A137-T140 WeakPolarHBondContact O-CB 3.35Å; A137-T140 PolarHBondContact O-N 2.73Å; M138-T140 PolarHBondContact O-N 3.48Å; T140-V142 VanDerWaalsContact C-N 3.34Å; T140-V142 PolarHBondContact O-N 3.22Å; T140-F143 PolarHBondContact O-N 2.99Å; T140-I144 HydrophobicContact CG2-CD1 4.01Å; T140-I144 WeakPolarHBondContact O-CG1 3.36Å; T140-I144 PolarHBondContact O-N 3.45Å
141	F	93.4	Very high	90.4	Very high	121 Å²	121	42.4 Å²	42.4	53%	0.531	23%	0.226	S	C	.	.	H	α-helix	trans	-62.4	-40.9	175	-72.7	-60.6	0	0	0	112.2	A137 M138 I144 F145	A137-F141 WeakPolarHBondContact O-CD2 3.46Å; A137-F141 PolarHBondContact O-N 3.37Å; M138-F141 PolarHBondContact O-N 3.15Å; M138-F141 HydrophobicContact SD-CD2 4.16Å; F141-I144 PolarHBondContact O-N 3.27Å; F141-F145 WeakPolarHBondContact O-CB 3.31Å; F141-F145 PolarHBondContact O-N 3.19Å
142	V	93.5	Very high	90.4	Very high	1 Å²	1	44.2 Å²	44.2	1%	0.006	24%	0.235	C	C	.	.	H	α-helix	trans	-69.7	-35.8	175.8	172.2	0	0	0	0	112.4	T54 M138 T140 S146 L176 M180 V246 L250	T54-V142 HydrophobicContact CG2-CG1 3.69Å; M138-V142 PolarHBondContact O-N 3.42Å; T140-V142 VanDerWaalsContact C-N 3.34Å; T140-V142 PolarHBondContact O-N 3.22Å; V142-S146 WeakPolarHBondContact O-CB 3.44Å; V142-S146 PolarHBondContact O-N 2.71Å; V142-S146 PolarHBondContact O-OG 2.91Å; V142-L176 HydrophobicContact CG2-CB 4.06Å; V142-L176 HydrophobicContact CG2-CD1 4.4Å; V142-L176 HydrophobicContact CG2-CD2 4.21Å; V142-L176 HydrophobicContact CG2-CG 4.46Å; V142-M180 HydrophobicContact CB-CG 4.44Å; V142-M180 HydrophobicContact CB-SD 4.31Å; V142-M180 HydrophobicContact CG2-CG 3.51Å; V142-M180 HydrophobicContact CG2-SD 3.76Å; V142-V246 HydrophobicContact CG1-CG1 3.92Å; V142-L250 HydrophobicContact CG1-CD1 4.09Å; V142-L250 HydrophobicContact CG1-CD2 4.29Å; V142-L250 HydrophobicContact CG2-CD1 4.23Å
143	F	94.6	Very high	90	Very high	69 Å²	69	44.2 Å²	44.2	30%	0.303	24%	0.235	S	C	.	.	H	α-helix	trans	-59.5	-51.7	171.7	179.1	-93.4	0	0	0	111	L55 C58 V59 A139 T140 F145 S146 L147	L55-F143 HydrophobicContact CB-CE2 4.47Å; L55-F143 HydrophobicContact CD2-CD2 3.49Å; L55-F143 VanDerWaalsContact CD2-CD2 3.49Å; L55-F143 HydrophobicContact CD2-CE2 3.6Å; L55-F143 HydrophobicContact CD2-CG 4.06Å; L55-F143 HydrophobicContact CD2-CZ 4.24Å; L55-F143 WeakPolarHBondContact CD2-O 3.47Å; C58-F143 HydrophobicContact CB-CB 3.95Å; C58-F143 HydrophobicContact CB-CD2 4.02Å; C58-F143 HydrophobicContact CB-CG 4.48Å; V59-F143 HydrophobicContact CG2-CD2 4.13Å; V59-F143 HydrophobicContact CG2-CE2 3.68Å; A139-F143 VanDerWaalsContact O-CB 3.31Å; A139-F143 WeakPolarHBondContact O-CB 3.45Å; A139-F143 PolarHBondContact O-N 2.9Å; T140-F143 PolarHBondContact O-N 2.99Å; F143-F145 PolarHBondContact O-N 3.11Å; F143-S146 PolarHBondContact O-N 2.66Å; F143-L147 HydrophobicContact CE1-CD1 3.81Å; F143-L147 HydrophobicContact CZ-CD1 4.09Å; F143-L147 VanDerWaalsContact O-CB 3.25Å; F143-L147 WeakPolarHBondContact O-CB 3.48Å; F143-L147 PolarHBondContact O-N 3.25Å
144	I	94.4	Very high	89.7	Confident	91 Å²	91	45.5 Å²	45.5	47%	0.467	24%	0.236	S	C	.	.	H	α-helix	trans	-61.3	-45.5	179.6	-66.3	166.8	0	0	0	111	T140 F141 L147 V148	T140-I144 HydrophobicContact CG2-CD1 4.01Å; T140-I144 WeakPolarHBondContact O-CG1 3.36Å; T140-I144 PolarHBondContact O-N 3.45Å; F141-I144 PolarHBondContact O-N 3.27Å; I144-L147 PolarHBondContact O-N 2.88Å; I144-V148 WeakPolarHBondContact O-CG2 3.39Å; I144-V148 PolarHBondContact O-N 3.24Å
145	F	92.4	Very high	89	Confident	30 Å²	30	45 Å²	45	13%	0.132	24%	0.241	C	C	.	.	H	α-helix	trans	-61.1	-47.1	176.4	174.8	-103	0	0	0	112.2	F141 F143 L147 V148 V149 V169 I172 C173 L176	F141-F145 WeakPolarHBondContact O-CB 3.31Å; F141-F145 PolarHBondContact O-N 3.19Å; F143-F145 PolarHBondContact O-N 3.11Å; F145-L147 VanDerWaalsContact C-N 3.28Å; F145-L147 PolarHBondContact O-N 3.47Å; F145-V148 PolarHBondContact O-N 3.08Å; F145-V149 HydrophobicContact CD1-CG2 4.35Å; F145-V149 HydrophobicContact CD2-CG2 4.29Å; F145-V149 HydrophobicContact CE1-CG2 3.97Å; F145-V149 HydrophobicContact CE2-CG2 3.89Å; F145-V149 HydrophobicContact CZ-CG2 3.72Å; F145-V149 WeakPolarHBondContact O-CB 3.31Å; F145-V149 WeakPolarHBondContact O-CG2 3.19Å; F145-V149 PolarHBondContact O-N 2.92Å; F145-V169 HydrophobicContact CZ-CG1 4.46Å; F145-I172 HydrophobicContact CD2-CB 4.44Å; F145-I172 HydrophobicContact CD2-CG2 3.64Å; F145-I172 HydrophobicContact CE2-CB 3.72Å; F145-I172 HydrophobicContact CE2-CD1 4.21Å; F145-I172 HydrophobicContact CE2-CG2 3.4Å; F145-I172 VanDerWaalsContact CE2-CG2 3.4Å; F145-I172 HydrophobicContact CG-CG2 4.39Å; F145-I172 HydrophobicContact CZ-CB 4.12Å; F145-I172 HydrophobicContact CZ-CG2 3.98Å; F145-C173 HydrophobicContact CE1-CB 4.39Å; F145-C173 HydrophobicContact CZ-CB 4.42Å; F145-L176 HydrophobicContact CB-CD1 3.55Å; F145-L176 HydrophobicContact CD1-CD1 3.45Å; F145-L176 VanDerWaalsContact CD1-CD1 3.45Å; F145-L176 HydrophobicContact CD2-CD1 3.94Å; F145-L176 HydrophobicContact CE1-CD1 4.08Å; F145-L176 HydrophobicContact CG-CD1 3.36Å
146	S	90.8	Very high	87.7	Confident	1 Å²	1	47.9 Å²	47.9	1%	0.007	26%	0.255	C	S	.	.	H	α-helix	trans	-64.8	-34.4	179.8	-56	0	0	0	0	111.8	T54 V142 F143 F150	T54-S146 WeakPolarHBondContact CG2-OG 3.45Å; V142-S146 WeakPolarHBondContact O-CB 3.44Å; V142-S146 PolarHBondContact O-N 2.71Å; V142-S146 PolarHBondContact O-OG 2.91Å; F143-S146 PolarHBondContact O-N 2.66Å; S146-F150 WeakPolarHBondContact O-CB 3.27Å; S146-F150 PolarHBondContact O-N 3.07Å
147	L	90.9	Very high	86.2	Confident	65 Å²	65	51.6 Å²	51.6	34%	0.34	27%	0.271	S	S	.	.	H	α-helix	trans	-67.3	-46.4	175.5	-176.3	153.2	0	0	0	111	L55 F143 I144 F145 F150 I151	L55-L147 HydrophobicContact CD2-CB 3.92Å; F143-L147 HydrophobicContact CE1-CD1 3.81Å; F143-L147 HydrophobicContact CZ-CD1 4.09Å; F143-L147 VanDerWaalsContact O-CB 3.25Å; F143-L147 WeakPolarHBondContact O-CB 3.48Å; F143-L147 PolarHBondContact O-N 3.25Å; I144-L147 PolarHBondContact O-N 2.88Å; F145-L147 VanDerWaalsContact C-N 3.28Å; F145-L147 PolarHBondContact O-N 3.47Å; L147-F150 PolarHBondContact O-N 3.47Å; L147-I151 HydrophobicContact CD2-CD1 3.55Å; L147-I151 HydrophobicContact CD2-CG1 4.36Å; L147-I151 HydrophobicContact CG-CD1 4.32Å; L147-I151 WeakPolarHBondContact O-CB 3.32Å; L147-I151 WeakPolarHBondContact O-CG1 3.31Å; L147-I151 PolarHBondContact O-N 3.29Å
148	V	90.3	Very high	84.5	Confident	73 Å²	73	54.4 Å²	54.4	44%	0.442	29%	0.289	S	S	.	.	H	α-helix	trans	-62.8	-44.8	176.2	169.5	0	0	0	0	111.1	I144 F145 I151 I152	I144-V148 WeakPolarHBondContact O-CG2 3.39Å; I144-V148 PolarHBondContact O-N 3.24Å; F145-V148 PolarHBondContact O-N 3.08Å; V148-I151 PolarHBondContact O-N 3.35Å; V148-I152 HydrophobicContact CG1-CD1 3.77Å; V148-I152 WeakPolarHBondContact O-CD1 3.42Å; V148-I152 VanDerWaalsContact O-CG1 3.28Å; V148-I152 WeakPolarHBondContact O-CG1 3.37Å; V148-I152 PolarHBondContact O-N 3.22Å
149	V	87.8	Confident	82.9	Confident	9 Å²	9	57.5 Å²	57.5	6%	0.055	31%	0.305	C	S	.	.	H	α-helix	trans	-61.4	-46.8	174.9	169.8	0	0	0	0	110.9	F145 I152 I153 F165 V169	F145-V149 HydrophobicContact CD1-CG2 4.35Å; F145-V149 HydrophobicContact CD2-CG2 4.29Å; F145-V149 HydrophobicContact CE1-CG2 3.97Å; F145-V149 HydrophobicContact CE2-CG2 3.89Å; F145-V149 HydrophobicContact CZ-CG2 3.72Å; F145-V149 WeakPolarHBondContact O-CB 3.31Å; F145-V149 WeakPolarHBondContact O-CG2 3.19Å; F145-V149 PolarHBondContact O-N 2.92Å; V149-I152 PolarHBondContact O-N 3.37Å; V149-I153 HydrophobicContact CG1-CD1 3.71Å; V149-I153 VanDerWaalsContact O-CG1 3.28Å; V149-I153 WeakPolarHBondContact O-CG1 3.38Å; V149-I153 PolarHBondContact O-N 2.98Å; V149-I153 VanDerWaalsContact O-N 3.11Å; V149-F165 HydrophobicContact CG1-CZ 4.38Å; V149-V169 HydrophobicContact CG2-CG2 4.1Å
150	F	88.6	Confident	81.4	Confident	60 Å²	60	57.4 Å²	57.4	26%	0.263	31%	0.305	S	S	.	.	H	α-helix	trans	-59.1	-50.4	177.8	177.4	-106.9	0	0	0	111.8	A51 I52 L55 S146 L147 I152 I153 V154	A51-F150 HydrophobicContact CB-CB 4.2Å; I52-F150 HydrophobicContact CD1-CE2 3.73Å; I52-F150 HydrophobicContact CD1-CZ 4.39Å; I52-F150 HydrophobicContact CG1-CD2 3.89Å; I52-F150 HydrophobicContact CG1-CE2 3.42Å; I52-F150 VanDerWaalsContact CG1-CE2 3.42Å; I52-F150 HydrophobicContact CG1-CZ 4.09Å; L55-F150 HydrophobicContact CD1-CB 4.24Å; L55-F150 HydrophobicContact CD1-CG 4.36Å; S146-F150 WeakPolarHBondContact O-CB 3.27Å; S146-F150 PolarHBondContact O-N 3.07Å; L147-F150 PolarHBondContact O-N 3.47Å; F150-I152 PolarHBondContact O-N 3.47Å; F150-I153 PolarHBondContact O-N 3.02Å; F150-V154 HydrophobicContact CD1-CG2 4.47Å; F150-V154 HydrophobicContact CD2-CG2 3.85Å; F150-V154 HydrophobicContact CE1-CG2 4.19Å; F150-V154 HydrophobicContact CE2-CG2 3.5Å; F150-V154 VanDerWaalsContact CE2-CG2 3.5Å; F150-V154 HydrophobicContact CG-CG2 4.32Å; F150-V154 HydrophobicContact CZ-CG2 3.71Å; F150-V154 VanDerWaalsContact O-CB 3.3Å; F150-V154 WeakPolarHBondContact O-CB 3.35Å; F150-V154 VanDerWaalsContact O-CG2 3.3Å; F150-V154 WeakPolarHBondContact O-CG2 3.49Å; F150-V154 PolarHBondContact O-N 3.07Å
151	I	87.1	Confident	80	Confident	95 Å²	95	58.3 Å²	58.3	49%	0.487	31%	0.305	S	S	.	.	H	α-helix	trans	-58.4	-45.5	177.9	-71.7	179.1	0	0	0	110.9	L147 V148 I153 V154 S155	L147-I151 HydrophobicContact CD2-CD1 3.55Å; L147-I151 HydrophobicContact CD2-CG1 4.36Å; L147-I151 HydrophobicContact CG-CD1 4.32Å; L147-I151 WeakPolarHBondContact O-CB 3.32Å; L147-I151 WeakPolarHBondContact O-CG1 3.31Å; L147-I151 PolarHBondContact O-N 3.29Å; V148-I151 PolarHBondContact O-N 3.35Å; I151-I153 PolarHBondContact O-N 3.3Å; I151-V154 PolarHBondContact O-N 3.41Å; I151-S155 WeakPolarHBondContact O-CB 3.47Å; I151-S155 PolarHBondContact O-N 3.18Å
152	I	83.5	Confident	78.7	Confident	39 Å²	39	54.4 Å²	54.4	20%	0.2	29%	0.293	C	S	.	.	H	α-helix	trans	-64	-41.4	-178.2	-68.2	165.2	0	0	0	111.8	V148 V149 F150 L159 F165	V148-I152 HydrophobicContact CG1-CD1 3.77Å; V148-I152 WeakPolarHBondContact O-CD1 3.42Å; V148-I152 VanDerWaalsContact O-CG1 3.28Å; V148-I152 WeakPolarHBondContact O-CG1 3.37Å; V148-I152 PolarHBondContact O-N 3.22Å; V149-I152 PolarHBondContact O-N 3.37Å; F150-I152 PolarHBondContact O-N 3.47Å; I152-L159 HydrophobicContact CG2-CB 4.24Å; I152-F165 HydrophobicContact CB-CE2 3.89Å; I152-F165 HydrophobicContact CB-CZ 4.1Å; I152-F165 HydrophobicContact CD1-CD2 4.26Å; I152-F165 HydrophobicContact CD1-CE2 3.79Å; I152-F165 HydrophobicContact CG1-CE2 4.45Å; I152-F165 HydrophobicContact CG2-CD2 3.83Å; I152-F165 HydrophobicContact CG2-CE1 4.27Å; I152-F165 HydrophobicContact CG2-CE2 3.53Å; I152-F165 HydrophobicContact CG2-CG 4.32Å; I152-F165 HydrophobicContact CG2-CZ 3.77Å
153	I	78.7	Confident	77.6	Confident	7 Å²	7	59.7 Å²	59.7	4%	0.036	31%	0.312	C	S	.	.	H	α-helix	trans	-77.7	-28.8	-179.8	-47.4	165.5	0	0	0	111.1	P44 L47 K48 V149 F150 I151 F165	P44-I153 HydrophobicContact CB-CG2 4.43Å; L47-I153 HydrophobicContact CB-CD1 4.08Å; K48-I153 HydrophobicContact CD-CG2 4.3Å; K48-I153 VanDerWaalsContact CE-CG2 3.45Å; K48-I153 WeakPolarHBondContact CE-O 3.43Å; K48-I153 HydrophobicContact CG-CB 4.19Å; K48-I153 HydrophobicContact CG-CG2 3.82Å; K48-I153 PolarHBondContact NZ-O 3.38Å; K48-I153 VanDerWaalsContact NZ-O 3.08Å; V149-I153 HydrophobicContact CG1-CD1 3.71Å; V149-I153 VanDerWaalsContact O-CG1 3.28Å; V149-I153 WeakPolarHBondContact O-CG1 3.38Å; V149-I153 PolarHBondContact O-N 2.98Å; V149-I153 VanDerWaalsContact O-N 3.11Å; F150-I153 PolarHBondContact O-N 3.02Å; I151-I153 PolarHBondContact O-N 3.3Å; I153-F165 HydrophobicContact CD1-CE1 4.22Å; I153-F165 HydrophobicContact CD1-CZ 4.27Å; I153-F165 HydrophobicContact CG1-CE1 3.74Å; I153-F165 HydrophobicContact CG1-CZ 3.81Å
154	V	80.5	Confident	76.8	Confident	63 Å²	63	64.6 Å²	64.6	38%	0.382	33%	0.334	S	S	.	.	H	α-helix	trans	-80.1	-34.6	176.6	171.2	0	0	0	0	113	K48 F150 I151 H156	K48-V154 HydrophobicContact CD-CG2 4.05Å; K48-V154 HydrophobicContact CG-CG2 4.39Å; F150-V154 HydrophobicContact CD1-CG2 4.47Å; F150-V154 HydrophobicContact CD2-CG2 3.85Å; F150-V154 HydrophobicContact CE1-CG2 4.19Å; F150-V154 HydrophobicContact CE2-CG2 3.5Å; F150-V154 VanDerWaalsContact CE2-CG2 3.5Å; F150-V154 HydrophobicContact CG-CG2 4.32Å; F150-V154 HydrophobicContact CZ-CG2 3.71Å; F150-V154 VanDerWaalsContact O-CB 3.3Å; F150-V154 WeakPolarHBondContact O-CB 3.35Å; F150-V154 VanDerWaalsContact O-CG2 3.3Å; F150-V154 WeakPolarHBondContact O-CG2 3.49Å; F150-V154 PolarHBondContact O-N 3.07Å; I151-V154 PolarHBondContact O-N 3.41Å; V154-H156 PolarHBondContact O-CD2 3.3Å; V154-H156 PolarHBondContact O-N 3.37Å; V154-H156 VanDerWaalsContact O-N 3.16Å
155	S	74	Confident	76.3	Confident	59 Å²	59	61.4 Å²	61.4	41%	0.413	32%	0.317	S	S	.	.	S	Bend	trans	-66.7	-14.3	179.9	-174.9	0	0	0	0	113.3	I151 Q157	I151-S155 WeakPolarHBondContact O-CB 3.47Å; I151-S155 PolarHBondContact O-N 3.18Å; S155-Q157 PolarHBondContact O-N 3Å; S155-Q157 WeakPolarHBondContact OG-CG 3.27Å
156	H	64.6	Low	75.8	Confident	64 Å²	64	60.1 Å²	60.1	30%	0.296	31%	0.311	S	S	.	.			trans	55.6	14	179.4	-78.5	-82.3	0	0	0	115.2	K48 V154	K48-H156 PolarHBondContact NZ-NE2 2.91Å; K48-H156 VanDerWaalsContact NZ-NE2 3.1Å; V154-H156 PolarHBondContact O-CD2 3.3Å; V154-H156 PolarHBondContact O-N 3.37Å; V154-H156 VanDerWaalsContact O-N 3.16Å
157	Q	57.5	Low	75.4	Confident	108 Å²	108	63.3 Å²	63.3	51%	0.505	33%	0.328	S	S	.	.			trans	-62.2	158.8	174.2	-74.8	-179.8	-0.5	0	0	112.1	S155 L159 S160	S155-Q157 PolarHBondContact O-N 3Å; S155-Q157 WeakPolarHBondContact OG-CG 3.27Å; Q157-L159 PolarHBondContact O-N 3.36Å; Q157-S160 WeakPolarHBondContact O-CB 3.36Å; Q157-S160 PolarHBondContact O-N 3.29Å; Q157-S160 PolarHBondContact O-OG 3.47Å
158	S	55.8	Low	75.2	Confident	96 Å²	96	62.3 Å²	62.3	67%	0.671	33%	0.328	S	S	*	.	G	3₁₀ helix	trans	-53.5	-24.2	178.9	54.5	0	0	0	0	114.3	S160 Q161 S162	S158-S160 VanDerWaalsContact C-N 3.33Å; S158-S160 PolarHBondContact O-N 3.45Å; S158-Q161 PolarHBondContact O-N 3.01Å; S158-S162 PolarHBondContact O-N 2.9Å
159	L	57.3	Low	75	Confident	94 Å²	94	59.3 Å²	59.3	49%	0.492	31%	0.31	S	S	.	.	G	3₁₀ helix	trans	-58.1	-40.6	172.4	-60.9	179.1	0	0	0	112.7	I152 Q157 Q161 S162 F165	I152-L159 HydrophobicContact CG2-CB 4.24Å; Q157-L159 PolarHBondContact O-N 3.36Å; L159-Q161 PolarHBondContact O-N 3.05Å; L159-S162 WeakPolarHBondContact O-CB 3.37Å; L159-S162 PolarHBondContact O-N 3.48Å; L159-F165 VanDerWaalsContact O-CB 3.26Å; L159-F165 WeakPolarHBondContact O-CB 3.46Å
160	S	60.2	Low	75.1	Confident	2 Å²	2	59.9 Å²	59.9	1%	0.014	31%	0.313	C	S	.	.	G	3₁₀ helix	trans	-65.5	-22.9	178.7	68.1	0	0	0	0	113.7	Q157 S158 Y166 W274	Q157-S160 WeakPolarHBondContact O-CB 3.36Å; Q157-S160 PolarHBondContact O-N 3.29Å; Q157-S160 PolarHBondContact O-OG 3.47Å; S158-S160 VanDerWaalsContact C-N 3.33Å; S158-S160 PolarHBondContact O-N 3.45Å; S160-Y166 WeakPolarHBondContact O-CE2 3.32Å; S160-Y166 PolarHBondContact O-OH 2.76Å; S160-W274 WeakPolarHBondContact O-CH2 3.48Å; S160-W274 WeakPolarHBondContact O-CZ3 3.37Å
161	Q	63.2	Low	75.2	Confident	78 Å²	78	61.8 Å²	61.8	36%	0.364	33%	0.325	S	S	.	.	G	3₁₀ helix	trans	-90.5	-2.8	177.4	-51.6	-176.7	-4.3	0	0	112.1	S158 L159 W274	S158-Q161 PolarHBondContact O-N 3.01Å; L159-Q161 PolarHBondContact O-N 3.05Å; Q161-W274 HydrophobicContact CB-CD2 4.38Å; Q161-W274 HydrophobicContact CB-CZ2 4.42Å; Q161-W274 HydrophobicContact CG-CB 4.42Å; Q161-W274 HydrophobicContact CG-CD2 3.77Å; Q161-W274 HydrophobicContact CG-CE3 4.25Å; Q161-W274 HydrophobicContact CG-CG 3.84Å
162	S	67.7	Low	75.4	Confident	39 Å²	39	60.7 Å²	60.7	27%	0.273	32%	0.319	S	S	.	.			trans	-84.1	128.6	-174.6	-173.5	0	0	0	0	112.2	S158 L159 K164 F165	S158-S162 PolarHBondContact O-N 2.9Å; L159-S162 WeakPolarHBondContact O-CB 3.37Å; L159-S162 PolarHBondContact O-N 3.48Å; S162-K164 PolarHBondContact O-N 2.75Å; S162-K164 WeakPolarHBondContact OG-CB 3.19Å; S162-K164 PolarHBondContact OG-N 2.85Å; S162-F165 PolarHBondContact O-N 2.78Å
163	R	68.8	Low	75.8	Confident	111 Å²	111	58.9 Å²	58.9	42%	0.419	31%	0.31	S	S	.	.	H	α-helix	trans	-54.8	-23.6	167.7	-72.3	-179.7	179.8	179.8	1.3	112.4	L167 I264	R163-L167 WeakPolarHBondContact O-CB 3.47Å; R163-L167 PolarHBondContact O-N 3.15Å; R163-I264 HydrophobicContact CG-CG2 3.55Å; R163-I264 VanDerWaalsContact CZ-O 3.28Å; R163-I264 PolarHBondContact NE-O 2.88Å; R163-I264 VanDerWaalsContact NE-O 3.16Å; R163-I264 PolarHBondContact NH2-O 3.46Å
164	K	79.6	Confident	76.5	Confident	172 Å²	172	60.9 Å²	60.9	75%	0.748	32%	0.323	S	S	*	.	H	α-helix	trans	-73.4	-32.6	175.5	-61.4	-176	178.6	-179.4	0	113.2	S162 L167 A168	S162-K164 PolarHBondContact O-N 2.75Å; S162-K164 WeakPolarHBondContact OG-CB 3.19Å; S162-K164 PolarHBondContact OG-N 2.85Å; K164-L167 WeakPolarHBondContact O-CB 3.37Å; K164-L167 PolarHBondContact O-N 2.93Å; K164-A168 PolarHBondContact O-N 3.24Å
165	F	82.4	Confident	77.1	Confident	25 Å²	25	62.4 Å²	62.4	11%	0.11	33%	0.329	C	S	.	.	H	α-helix	trans	-67.1	-53.1	-179.9	170	-108.5	0	0	0	111.3	V149 I152 I153 L159 S162 L167 A168 V169	V149-F165 HydrophobicContact CG1-CZ 4.38Å; I152-F165 HydrophobicContact CB-CE2 3.89Å; I152-F165 HydrophobicContact CB-CZ 4.1Å; I152-F165 HydrophobicContact CD1-CD2 4.26Å; I152-F165 HydrophobicContact CD1-CE2 3.79Å; I152-F165 HydrophobicContact CG1-CE2 4.45Å; I152-F165 HydrophobicContact CG2-CD2 3.83Å; I152-F165 HydrophobicContact CG2-CE1 4.27Å; I152-F165 HydrophobicContact CG2-CE2 3.53Å; I152-F165 HydrophobicContact CG2-CG 4.32Å; I152-F165 HydrophobicContact CG2-CZ 3.77Å; I153-F165 HydrophobicContact CD1-CE1 4.22Å; I153-F165 HydrophobicContact CD1-CZ 4.27Å; I153-F165 HydrophobicContact CG1-CE1 3.74Å; I153-F165 HydrophobicContact CG1-CZ 3.81Å; L159-F165 VanDerWaalsContact O-CB 3.26Å; L159-F165 WeakPolarHBondContact O-CB 3.46Å; S162-F165 PolarHBondContact O-N 2.78Å; F165-L167 PolarHBondContact O-N 3.25Å; F165-A168 PolarHBondContact O-N 3.04Å; F165-V169 HydrophobicContact CD2-CG2 4.35Å; F165-V169 HydrophobicContact CE1-CG2 4.25Å; F165-V169 HydrophobicContact CE2-CG2 3.91Å; F165-V169 HydrophobicContact CZ-CG2 3.86Å; F165-V169 WeakPolarHBondContact O-CG2 3.48Å; F165-V169 PolarHBondContact O-N 2.97Å
166	Y	81.6	Confident	78	Confident	2 Å²	2	60.6 Å²	60.6	1%	0.008	31%	0.314	C	S	.	.	H	α-helix	trans	-62.9	-28.3	175.3	-63.5	-77.7	0	0	0	112.7	L47 S160 L170 T260 I264 W274	L47-Y166 HydrophobicContact CD1-CD1 4.41Å; L47-Y166 HydrophobicContact CD1-CE1 3.87Å; S160-Y166 WeakPolarHBondContact O-CE2 3.32Å; S160-Y166 PolarHBondContact O-OH 2.76Å; Y166-L170 VanDerWaalsContact O-CB 3.29Å; Y166-L170 WeakPolarHBondContact O-CB 3.4Å; Y166-L170 WeakPolarHBondContact O-CD1 3.16Å; Y166-L170 WeakPolarHBondContact O-CG 3.47Å; Y166-L170 PolarHBondContact O-N 2.89Å; Y166-T260 HydrophobicContact CD1-CG2 4Å; Y166-T260 HydrophobicContact CE1-CG2 3.54Å; Y166-T260 HydrophobicContact CE2-CG2 4.14Å; Y166-T260 HydrophobicContact CG-CG2 4.49Å; Y166-I264 HydrophobicContact CD2-CD1 3.79Å; Y166-I264 HydrophobicContact CE2-CD1 3.64Å; Y166-W274 AromaticContact CE2-CH2 3.81Å; Y166-W274 HydrophobicContact CE2-CH2 3.81Å; Y166-W274 WeakPolarHBondContact OH-CH2 3.5Å; Y166-W274 WeakPolarHBondContact OH-CZ3 3.28Å
167	L	84.1	Confident	79.4	Confident	69 Å²	69	58 Å²	58	36%	0.361	30%	0.304	S	S	.	.	H	α-helix	trans	-63.8	-47.1	171	-173.3	159	0	0	0	111.5	R163 K164 F165 L170 I171	R163-L167 WeakPolarHBondContact O-CB 3.47Å; R163-L167 PolarHBondContact O-N 3.15Å; K164-L167 WeakPolarHBondContact O-CB 3.37Å; K164-L167 PolarHBondContact O-N 2.93Å; F165-L167 PolarHBondContact O-N 3.25Å; L167-L170 PolarHBondContact O-N 2.95Å; L167-I171 HydrophobicContact CD2-CD1 3.63Å; L167-I171 HydrophobicContact CD2-CG1 4.49Å; L167-I171 PolarHBondContact O-N 2.88Å
168	A	85	Confident	81.2	Confident	43 Å²	43	57.7 Å²	57.7	36%	0.355	31%	0.305	S	S	.	.	H	α-helix	trans	-63.4	-44.9	177.5	0	0	0	0	0	112.2	K164 F165 L170 I171 I172	K164-A168 PolarHBondContact O-N 3.24Å; F165-A168 PolarHBondContact O-N 3.04Å; A168-L170 VanDerWaalsContact C-N 3.28Å; A168-L170 PolarHBondContact O-N 3.35Å; A168-I171 PolarHBondContact O-N 3.3Å; A168-I171 VanDerWaalsContact O-N 3.12Å; A168-I172 WeakPolarHBondContact O-CG1 3.42Å; A168-I172 PolarHBondContact O-N 2.85Å
169	V	87.9	Confident	83	Confident	10 Å²	10	55.8 Å²	55.8	6%	0.061	29%	0.287	C	S	.	.	H	α-helix	trans	-57.4	-42.3	175	174.3	0	0	0	0	111	F145 V149 F165 I171 I172 C173 A257	F145-V169 HydrophobicContact CZ-CG1 4.46Å; V149-V169 HydrophobicContact CG2-CG2 4.1Å; F165-V169 HydrophobicContact CD2-CG2 4.35Å; F165-V169 HydrophobicContact CE1-CG2 4.25Å; F165-V169 HydrophobicContact CE2-CG2 3.91Å; F165-V169 HydrophobicContact CZ-CG2 3.86Å; F165-V169 WeakPolarHBondContact O-CG2 3.48Å; F165-V169 PolarHBondContact O-N 2.97Å; V169-I171 VanDerWaalsContact C-N 3.29Å; V169-I171 PolarHBondContact O-N 3.38Å; V169-I172 PolarHBondContact O-N 3.24Å; V169-C173 WeakPolarHBondContact O-CB 3.32Å; V169-C173 PolarHBondContact O-N 2.63Å; V169-A257 HydrophobicContact CG1-CB 4.1Å
170	L	88	Confident	84.7	Confident	22 Å²	22	51.4 Å²	51.4	12%	0.115	26%	0.264	C	S	.	.	H	α-helix	trans	-68.4	-20.6	178.6	-76.9	169.2	0	0	0	115.1	Y166 L167 A168 P174 L254 A257 L258 R261	Y166-L170 VanDerWaalsContact O-CB 3.29Å; Y166-L170 WeakPolarHBondContact O-CB 3.4Å; Y166-L170 WeakPolarHBondContact O-CD1 3.16Å; Y166-L170 WeakPolarHBondContact O-CG 3.47Å; Y166-L170 PolarHBondContact O-N 2.89Å; L167-L170 PolarHBondContact O-N 2.95Å; A168-L170 VanDerWaalsContact C-N 3.28Å; A168-L170 PolarHBondContact O-N 3.35Å; L170-P174 WeakPolarHBondContact O-CD 3.31Å; L170-P174 VanDerWaalsContact O-CG 3.31Å; L170-P174 WeakPolarHBondContact O-CG 3.18Å; L170-L254 HydrophobicContact CD2-CG 4.25Å; L170-A257 HydrophobicContact CD2-CB 3.77Å; L170-A257 HydrophobicContact CG-CB 3.96Å; L170-L258 HydrophobicContact CD1-CD2 3.92Å; L170-L258 HydrophobicContact CD2-CB 4.38Å; L170-L258 HydrophobicContact CD2-CD2 3.6Å; L170-L258 HydrophobicContact CD2-CG 3.59Å; L170-L258 HydrophobicContact CG-CD2 4.4Å; L170-R261 HydrophobicContact CD1-CB 4.22Å
171	I	91.1	Very high	86.4	Confident	99 Å²	99	54.7 Å²	54.7	51%	0.508	28%	0.281	S	S	.	.	H	α-helix	trans	-88.7	-43	174.9	-66.6	175.3	0	0	0	110.6	L167 A168 V169 P174 I175	L167-I171 HydrophobicContact CD2-CD1 3.63Å; L167-I171 HydrophobicContact CD2-CG1 4.49Å; L167-I171 PolarHBondContact O-N 2.88Å; A168-I171 PolarHBondContact O-N 3.3Å; A168-I171 VanDerWaalsContact O-N 3.12Å; V169-I171 VanDerWaalsContact C-N 3.29Å; V169-I171 PolarHBondContact O-N 3.38Å; I171-P174 WeakPolarHBondContact O-CD 3.24Å; I171-P174 WeakPolarHBondContact O-CG 3.45Å; I171-I175 HydrophobicContact CG2-CD1 4.45Å; I171-I175 WeakPolarHBondContact O-CD1 3.22Å; I171-I175 WeakPolarHBondContact O-CG1 3.22Å
172	I	91.3	Very high	87.8	Confident	72 Å²	72	54.5 Å²	54.5	37%	0.369	28%	0.281	S	S	.	.	H	α-helix	trans	-79.9	-40	-173	-60.4	166	0	0	0	111.7	F145 A168 V169 I175 L176	F145-I172 HydrophobicContact CD2-CB 4.44Å; F145-I172 HydrophobicContact CD2-CG2 3.64Å; F145-I172 HydrophobicContact CE2-CB 3.72Å; F145-I172 HydrophobicContact CE2-CD1 4.21Å; F145-I172 HydrophobicContact CE2-CG2 3.4Å; F145-I172 VanDerWaalsContact CE2-CG2 3.4Å; F145-I172 HydrophobicContact CG-CG2 4.39Å; F145-I172 HydrophobicContact CZ-CB 4.12Å; F145-I172 HydrophobicContact CZ-CG2 3.98Å; A168-I172 WeakPolarHBondContact O-CG1 3.42Å; A168-I172 PolarHBondContact O-N 2.85Å; V169-I172 PolarHBondContact O-N 3.24Å; I172-I175 PolarHBondContact O-N 3.43Å; I172-L176 HydrophobicContact CG2-CD1 3.72Å; I172-L176 HydrophobicContact CG2-CG 4.06Å; I172-L176 PolarHBondContact O-N 3.03Å
173	C	92.1	Very high	88.9	Confident	1 Å²	1	52.6 Å²	52.6	1%	0.007	27%	0.269	C	S	.	.	H	α-helix	trans	-58.4	-45.3	-177.7	-163.9	0	0	0	0	114.8	F145 V169 I175 L176 A177 L250	F145-C173 HydrophobicContact CE1-CB 4.39Å; F145-C173 HydrophobicContact CZ-CB 4.42Å; V169-C173 WeakPolarHBondContact O-CB 3.32Å; V169-C173 PolarHBondContact O-N 2.63Å; C173-I175 VanDerWaalsContact C-N 3.33Å; C173-I175 PolarHBondContact O-N 3Å; C173-L176 PolarHBondContact O-N 3.49Å; C173-A177 WeakPolarHBondContact O-CB 3.45Å; C173-A177 PolarHBondContact O-N 3.04Å; C173-L250 PolarHBondContact SG-O 3.16Å
174	P	93.1	Very high	90.1	Very high	49 Å²	49	47.4 Å²	47.4	32%	0.318	25%	0.249	S	C	.	.	H	α-helix	trans	-65.8	-34.1	176.3	22.7	-30.4	0	0	0	113.2	L170 I171 A177 L178 L254	L170-P174 WeakPolarHBondContact O-CD 3.31Å; L170-P174 VanDerWaalsContact O-CG 3.31Å; L170-P174 WeakPolarHBondContact O-CG 3.18Å; I171-P174 WeakPolarHBondContact O-CD 3.24Å; I171-P174 WeakPolarHBondContact O-CG 3.45Å; P174-A177 PolarHBondContact O-N 3.25Å; P174-L178 WeakPolarHBondContact O-CB 3.48Å; P174-L178 PolarHBondContact O-N 3.49Å; P174-L254 HydrophobicContact CB-CD1 3.59Å; P174-L254 HydrophobicContact CG-CD1 3.92Å
175	I	94.3	Very high	90.6	Very high	96 Å²	96	43.1 Å²	43.1	49%	0.492	23%	0.233	S	C	.	.	H	α-helix	trans	-65.2	-47	177	-60.6	171.9	0	0	0	109.3	I171 I172 C173 L178 L179	I171-I175 HydrophobicContact CG2-CD1 4.45Å; I171-I175 WeakPolarHBondContact O-CD1 3.22Å; I171-I175 WeakPolarHBondContact O-CG1 3.22Å; I172-I175 PolarHBondContact O-N 3.43Å; C173-I175 VanDerWaalsContact C-N 3.33Å; C173-I175 PolarHBondContact O-N 3Å; I175-L178 PolarHBondContact O-N 3.03Å; I175-L179 HydrophobicContact CG2-CD1 3.98Å; I175-L179 HydrophobicContact CG2-CG 4.49Å; I175-L179 WeakPolarHBondContact O-CB 3.44Å; I175-L179 VanDerWaalsContact O-CG 3.31Å; I175-L179 WeakPolarHBondContact O-CG 3.33Å; I175-L179 PolarHBondContact O-N 3.42Å
176	L	93.4	Very high	90.9	Very high	21 Å²	21	44.1 Å²	44.1	11%	0.11	24%	0.242	C	C	.	.	H	α-helix	trans	-65.7	-37.4	176.3	-70.4	178.7	0	0	0	113	V142 F145 I172 C173 L179 M180	V142-L176 HydrophobicContact CG2-CB 4.06Å; V142-L176 HydrophobicContact CG2-CD1 4.4Å; V142-L176 HydrophobicContact CG2-CD2 4.21Å; V142-L176 HydrophobicContact CG2-CG 4.46Å; F145-L176 HydrophobicContact CB-CD1 3.55Å; F145-L176 HydrophobicContact CD1-CD1 3.45Å; F145-L176 VanDerWaalsContact CD1-CD1 3.45Å; F145-L176 HydrophobicContact CD2-CD1 3.94Å; F145-L176 HydrophobicContact CE1-CD1 4.08Å; F145-L176 HydrophobicContact CG-CD1 3.36Å; I172-L176 HydrophobicContact CG2-CD1 3.72Å; I172-L176 HydrophobicContact CG2-CG 4.06Å; I172-L176 PolarHBondContact O-N 3.03Å; C173-L176 PolarHBondContact O-N 3.49Å; L176-L179 PolarHBondContact O-N 2.65Å; L176-M180 WeakPolarHBondContact O-CB 3.31Å; L176-M180 WeakPolarHBondContact O-CG 3.44Å; L176-M180 PolarHBondContact O-N 2.87Å
177	A	93.9	Very high	91.3	Very high	9 Å²	9	44 Å²	44	7%	0.074	24%	0.241	C	C	.	.	H	α-helix	trans	-62.3	-43.6	174.7	0	0	0	0	0	111.9	C173 P174 L181 L250 I251	C173-A177 WeakPolarHBondContact O-CB 3.45Å; C173-A177 PolarHBondContact O-N 3.04Å; P174-A177 PolarHBondContact O-N 3.25Å; A177-L181 WeakPolarHBondContact O-CB 3.35Å; A177-L181 PolarHBondContact O-N 3.05Å; A177-L250 HydrophobicContact CB-CB 3.82Å; A177-L250 HydrophobicContact CB-CD1 4.34Å; A177-I251 HydrophobicContact CB-CG1 4.38Å
178	L	94.8	Very high	91.4	Very high	102 Å²	102	43.6 Å²	43.6	53%	0.534	24%	0.239	S	C	.	.	H	α-helix	trans	-66.2	-43.5	176.4	-175.9	153.2	0	0	0	111.6	P174 I175 L181 I182	P174-L178 WeakPolarHBondContact O-CB 3.48Å; P174-L178 PolarHBondContact O-N 3.49Å; I175-L178 PolarHBondContact O-N 3.03Å; L178-L181 PolarHBondContact O-N 3.48Å; L178-I182 HydrophobicContact CD2-CD1 3.59Å; L178-I182 HydrophobicContact CD2-CG1 4.35Å; L178-I182 WeakPolarHBondContact O-CG1 3.33Å; L178-I182 PolarHBondContact O-N 3.08Å
179	L	93.1	Very high	91.4	Very high	56 Å²	56	43.3 Å²	43.3	29%	0.293	23%	0.232	S	C	.	.	H	α-helix	trans	-65.7	-38.5	177.3	-71.4	173.4	0	0	0	112.4	M138 I175 L176 I182 A183	M138-L179 HydrophobicContact SD-CB 4.1Å; M138-L179 HydrophobicContact SD-CD1 4.43Å; I175-L179 HydrophobicContact CG2-CD1 3.98Å; I175-L179 HydrophobicContact CG2-CG 4.49Å; I175-L179 WeakPolarHBondContact O-CB 3.44Å; I175-L179 VanDerWaalsContact O-CG 3.31Å; I175-L179 WeakPolarHBondContact O-CG 3.33Å; I175-L179 PolarHBondContact O-N 3.42Å; L176-L179 PolarHBondContact O-N 2.65Å; L179-I182 PolarHBondContact O-N 3.39Å; L179-A183 VanDerWaalsContact O-CB 3.3Å; L179-A183 WeakPolarHBondContact O-CB 3.37Å; L179-A183 PolarHBondContact O-N 3.39Å
180	M	93.4	Very high	91.1	Very high	1 Å²	1	42.8 Å²	42.8	1%	0.005	23%	0.23	C	C	.	.	H	α-helix	trans	-64.4	-44	171.7	-75.9	-57.8	-56.9	0	0	112	M138 V142 L176 I182 A183 T184 V246 L250	M138-M180 VanDerWaalsContact C-SD 3.56Å; M138-M180 HydrophobicContact CB-SD 3.77Å; V142-M180 HydrophobicContact CB-CG 4.44Å; V142-M180 HydrophobicContact CB-SD 4.31Å; V142-M180 HydrophobicContact CG2-CG 3.51Å; V142-M180 HydrophobicContact CG2-SD 3.76Å; L176-M180 WeakPolarHBondContact O-CB 3.31Å; L176-M180 WeakPolarHBondContact O-CG 3.44Å; L176-M180 PolarHBondContact O-N 2.87Å; M180-I182 VanDerWaalsContact C-N 3.33Å; M180-I182 PolarHBondContact O-N 2.93Å; M180-A183 CarbonylContact O-C 3.59Å; M180-A183 PolarHBondContact O-N 3.3Å; M180-A183 VanDerWaalsContact O-N 3.13Å; M180-T184 WeakPolarHBondContact O-CG2 3.32Å; M180-T184 PolarHBondContact O-N 2.93Å; M180-T184 PolarHBondContact O-OG1 2.91Å; M180-T184 VanDerWaalsContact O-OG1 3.14Å; M180-V246 HydrophobicContact CE-CG1 4.05Å; M180-V246 HydrophobicContact CG-CG1 4.15Å; M180-L250 HydrophobicContact CB-CD1 4.49Å; M180-L250 HydrophobicContact CG-CD1 4.05Å
181	L	94.6	Very high	90.7	Very high	72 Å²	72	42.1 Å²	42.1	38%	0.377	23%	0.226	S	C	.	.	H	α-helix	trans	-59.9	-43.1	177.3	-176.2	149.5	0	0	0	111.6	A177 L178 T184 I185 T247	A177-L181 WeakPolarHBondContact O-CB 3.35Å; A177-L181 PolarHBondContact O-N 3.05Å; L178-L181 PolarHBondContact O-N 3.48Å; L181-T184 PolarHBondContact O-OG1 3.44Å; L181-I185 HydrophobicContact CD2-CD1 3.65Å; L181-I185 HydrophobicContact CG-CD1 4.39Å; L181-I185 WeakPolarHBondContact O-CG1 3.49Å; L181-I185 PolarHBondContact O-N 3.43Å; L181-I185 VanDerWaalsContact O-N 3.1Å; L181-T247 HydrophobicContact CB-CG2 3.99Å; L181-T247 HydrophobicContact CD1-CG2 4.18Å
182	I	93.4	Very high	90.2	Very high	73 Å²	73	39.6 Å²	39.6	37%	0.374	21%	0.213	S	C	.	.	H	α-helix	trans	-64.1	-45.7	173.2	-68	177.7	0	0	0	110.3	F134 L178 L179 M180 T184 I185 V186	F134-I182 HydrophobicContact CE1-CG2 4.37Å; L178-I182 HydrophobicContact CD2-CD1 3.59Å; L178-I182 HydrophobicContact CD2-CG1 4.35Å; L178-I182 WeakPolarHBondContact O-CG1 3.33Å; L178-I182 PolarHBondContact O-N 3.08Å; L179-I182 PolarHBondContact O-N 3.39Å; M180-I182 VanDerWaalsContact C-N 3.33Å; M180-I182 PolarHBondContact O-N 2.93Å; I182-T184 VanDerWaalsContact C-N 3.33Å; I182-T184 PolarHBondContact O-N 3.28Å; I182-I185 PolarHBondContact O-N 3.19Å; I182-V186 HydrophobicContact CG2-CG2 4.12Å; I182-V186 WeakPolarHBondContact O-CB 3.42Å; I182-V186 VanDerWaalsContact O-CG2 3.3Å; I182-V186 WeakPolarHBondContact O-CG2 3.32Å; I182-V186 PolarHBondContact O-N 3.47Å
183	A	92	Very high	89.2	Confident	0 Å²	0	36.2 Å²	36.2	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-61.3	-37.7	179	0	0	0	0	0	113	F134 M138 L179 M180 Y187	F134-A183 HydrophobicContact CD1-CB 3.99Å; F134-A183 HydrophobicContact CE1-CB 3.78Å; M138-A183 HydrophobicContact CB-CB 3.9Å; M138-A183 HydrophobicContact CG-CB 3.96Å; L179-A183 VanDerWaalsContact O-CB 3.3Å; L179-A183 WeakPolarHBondContact O-CB 3.37Å; L179-A183 PolarHBondContact O-N 3.39Å; M180-A183 CarbonylContact O-C 3.59Å; M180-A183 PolarHBondContact O-N 3.3Å; M180-A183 VanDerWaalsContact O-N 3.13Å; A183-Y187 WeakPolarHBondContact O-CB 3.47Å; A183-Y187 PolarHBondContact O-N 3.15Å
184	T	92.6	Very high	88	Confident	1 Å²	1	38.2 Å²	38.2	1%	0.006	21%	0.21	C	C	.	.	H	α-helix	trans	-73.2	-34.6	177.2	52.5	0	0	0	0	112.8	M180 L181 I182 L188 G243	M180-T184 WeakPolarHBondContact O-CG2 3.32Å; M180-T184 PolarHBondContact O-N 2.93Å; M180-T184 PolarHBondContact O-OG1 2.91Å; M180-T184 VanDerWaalsContact O-OG1 3.14Å; L181-T184 PolarHBondContact O-OG1 3.44Å; I182-T184 VanDerWaalsContact C-N 3.33Å; I182-T184 PolarHBondContact O-N 3.28Å; T184-L188 VanDerWaalsContact O-CB 3.28Å; T184-L188 WeakPolarHBondContact O-CB 3.45Å; T184-L188 PolarHBondContact O-N 3.44Å; T184-G243 VanDerWaalsContact CG2-CA 3.48Å
185	I	90.9	Very high	86.7	Confident	82 Å²	82	38 Å²	38	42%	0.421	21%	0.21	S	C	.	.	H	α-helix	trans	-69.1	-47	173	-68.8	172.2	0	0	0	110.3	L181 I182 Y187 L188 V189	L181-I185 HydrophobicContact CD2-CD1 3.65Å; L181-I185 HydrophobicContact CG-CD1 4.39Å; L181-I185 WeakPolarHBondContact O-CG1 3.49Å; L181-I185 PolarHBondContact O-N 3.43Å; L181-I185 VanDerWaalsContact O-N 3.1Å; I182-I185 PolarHBondContact O-N 3.19Å; I185-Y187 VanDerWaalsContact C-N 3.31Å; I185-Y187 PolarHBondContact O-N 3.44Å; I185-L188 PolarHBondContact O-N 3.18Å; I185-V189 VanDerWaalsContact O-CG2 3.32Å; I185-V189 WeakPolarHBondContact O-CG2 3.23Å; I185-V189 PolarHBondContact O-N 3.3Å
186	V	88.8	Confident	85.5	Confident	47 Å²	47	33.5 Å²	33.5	29%	0.285	19%	0.187	S	C	.	.	H	α-helix	trans	-60.2	-42.1	176.2	169.8	0	0	0	0	110.8	F134 I182 V189 A190	F134-V186 HydrophobicContact CD1-CB 4.26Å; F134-V186 HydrophobicContact CD1-CG1 4.05Å; F134-V186 HydrophobicContact CE1-CB 4.44Å; F134-V186 HydrophobicContact CE1-CG2 4.48Å; I182-V186 HydrophobicContact CG2-CG2 4.12Å; I182-V186 WeakPolarHBondContact O-CB 3.42Å; I182-V186 VanDerWaalsContact O-CG2 3.3Å; I182-V186 WeakPolarHBondContact O-CG2 3.32Å; I182-V186 PolarHBondContact O-N 3.47Å; V186-V189 PolarHBondContact O-N 3.04Å; V186-A190 WeakPolarHBondContact O-CB 3.49Å; V186-A190 PolarHBondContact O-N 3.48Å
187	Y	88.7	Confident	83.9	Confident	0 Å²	0	36.8 Å²	36.8	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-63.5	-47.1	175.5	177.8	-122.4	0	0	0	112.3	V65 K132 M135 A183 I185 V189 A190 I191 E236 A239 V240	V65-Y187 HydrophobicContact CG2-CE1 4.31Å; V65-Y187 HydrophobicContact CG2-CE2 4.19Å; K132-Y187 HydrophobicContact CG-CD2 4.27Å; K132-Y187 HydrophobicContact CG-CE2 3.76Å; M135-Y187 HydrophobicContact CB-CD2 4.23Å; M135-Y187 HydrophobicContact CB-CG 4.14Å; M135-Y187 HydrophobicContact CG-CD1 3.99Å; M135-Y187 HydrophobicContact CG-CD2 4.25Å; M135-Y187 HydrophobicContact CG-CG 3.77Å; A183-Y187 WeakPolarHBondContact O-CB 3.47Å; A183-Y187 PolarHBondContact O-N 3.15Å; I185-Y187 VanDerWaalsContact C-N 3.31Å; I185-Y187 PolarHBondContact O-N 3.44Å; Y187-V189 VanDerWaalsContact C-N 3.31Å; Y187-V189 PolarHBondContact O-N 3.11Å; Y187-A190 PolarHBondContact O-N 3.29Å; Y187-I191 HydrophobicContact CD2-CG2 3.83Å; Y187-I191 HydrophobicContact CE1-CD1 4.24Å; Y187-I191 HydrophobicContact CE2-CG2 3.29Å; Y187-I191 WeakPolarHBondContact O-CG1 3.46Å; Y187-I191 PolarHBondContact O-N 3.49Å; Y187-E236 WeakPolarHBondContact OH-CA 3.5Å; Y187-E236 VanDerWaalsContact OH-CB 3.3Å; Y187-E236 WeakPolarHBondContact OH-CB 3.34Å; Y187-E236 WeakPolarHBondContact OH-CG 3.48Å; Y187-A239 HydrophobicContact CE1-CB 3.8Å; Y187-V240 HydrophobicContact CD1-CG2 3.67Å; Y187-V240 HydrophobicContact CE1-CG2 3.72Å
188	L	87.7	Confident	82.4	Confident	60 Å²	60	41.9 Å²	41.9	31%	0.314	24%	0.243	S	C	.	.	H	α-helix	trans	-55.8	-45.5	175	-171.3	167.6	0	0	0	111.4	T184 I185 A190 I191 N192 V240	T184-L188 VanDerWaalsContact O-CB 3.28Å; T184-L188 WeakPolarHBondContact O-CB 3.45Å; T184-L188 PolarHBondContact O-N 3.44Å; I185-L188 PolarHBondContact O-N 3.18Å; L188-A190 VanDerWaalsContact C-N 3.31Å; L188-A190 PolarHBondContact O-N 2.71Å; L188-I191 WeakPolarHBondContact O-CG1 3.14Å; L188-I191 PolarHBondContact O-N 2.96Å; L188-N192 PolarHBondContact O-N 3.06Å; L188-N192 VanDerWaalsContact O-N 3.11Å; L188-V240 HydrophobicContact CB-CG2 4.34Å; L188-V240 HydrophobicContact CD1-CG1 4.14Å
189	V	84.8	Confident	81	Confident	36 Å²	36	38.6 Å²	38.6	22%	0.218	23%	0.227	C	C	.	.	H	α-helix	trans	-67.8	-31.9	177.8	176.3	0	0	0	0	112.1	N126 I185 V186 Y187 S195 Q196	N126-V189 WeakPolarHBondContact ND2-CG1 3.27Å; I185-V189 VanDerWaalsContact O-CG2 3.32Å; I185-V189 WeakPolarHBondContact O-CG2 3.23Å; I185-V189 PolarHBondContact O-N 3.3Å; V186-V189 PolarHBondContact O-N 3.04Å; Y187-V189 VanDerWaalsContact C-N 3.31Å; Y187-V189 PolarHBondContact O-N 3.11Å; V189-S195 WeakPolarHBondContact CA-OG 3.32Å; V189-Q196 HydrophobicContact CG1-CG 3.65Å; V189-Q196 PolarHBondContact O-NE2 2.74Å
190	A	81.6	Confident	79.7	Confident	0 Å²	0	40.6 Å²	40.6	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-77.6	-30.5	178.8	0	0	0	0	0	113.8	V186 Y187 L188 Y229	V186-A190 WeakPolarHBondContact O-CB 3.49Å; V186-A190 PolarHBondContact O-N 3.48Å; Y187-A190 PolarHBondContact O-N 3.29Å; L188-A190 VanDerWaalsContact C-N 3.31Å; L188-A190 PolarHBondContact O-N 2.71Å; A190-Y229 WeakPolarHBondContact O-CE2 3.46Å
191	I	80.2	Confident	78.4	Confident	7 Å²	7	43.7 Å²	43.7	4%	0.036	25%	0.253	C	S	.	.	H	α-helix	trans	-86.7	-22.6	175.8	64.9	178.4	0	0	0	113.8	Y187 L188 P193 V232 E236 V240	Y187-I191 HydrophobicContact CD2-CG2 3.83Å; Y187-I191 HydrophobicContact CE1-CD1 4.24Å; Y187-I191 HydrophobicContact CE2-CG2 3.29Å; Y187-I191 WeakPolarHBondContact O-CG1 3.46Å; Y187-I191 PolarHBondContact O-N 3.49Å; L188-I191 WeakPolarHBondContact O-CG1 3.14Å; L188-I191 PolarHBondContact O-N 2.96Å; I191-P193 WeakPolarHBondContact O-CD 3.4Å; I191-V232 HydrophobicContact CD1-CG1 4.03Å; I191-E236 HydrophobicContact CD1-CB 3.77Å; I191-E236 HydrophobicContact CG2-CB 4.35Å; I191-E236 HydrophobicContact CG2-CG 4.38Å; I191-V240 HydrophobicContact CD1-CG2 3.75Å
192	N	79.1	Confident	77.2	Confident	46 Å²	46	40.2 Å²	40.2	25%	0.246	24%	0.235	C	C	.	.			trans	-117.9	92.3	-178.9	-170.7	-9.5	0	0	0	111.5	L188 S194 S195 V232	L188-N192 PolarHBondContact O-N 3.06Å; L188-N192 VanDerWaalsContact O-N 3.11Å; N192-S194 PolarHBondContact O-N 3.21Å; N192-S194 VanDerWaalsContact O-N 3.1Å; N192-S194 WeakPolarHBondContact OD1-CA 3.35Å; N192-S194 WeakPolarHBondContact OD1-CB 3.43Å; N192-S194 PolarHBondContact OD1-N 3.35Å; N192-S194 PolarHBondContact OD1-OG 3.4Å; N192-S195 WeakPolarHBondContact O-CB 3.49Å; N192-S195 PolarHBondContact O-N 3.18Å; N192-S195 PolarHBondContact O-OG 2.76Å; N192-V232 HydrophobicContact CB-CG2 3.85Å
193	P	71.1	Confident	76.2	Confident	1 Å²	1	40.9 Å²	40.9	1%	0.006	25%	0.246	C	C	.	.	G	3₁₀ helix	trans	-55.9	-27.2	175.9	19.2	-31.8	0	0	0	113.9	I191 S195 Q196 I205 Y229	I191-P193 WeakPolarHBondContact O-CD 3.4Å; P193-S195 PolarHBondContact O-N 2.99Å; P193-S195 VanDerWaalsContact O-N 3.12Å; P193-Q196 WeakPolarHBondContact O-CB 3.27Å; P193-Q196 PolarHBondContact O-N 3.29Å; P193-I205 HydrophobicContact CB-CG2 3.46Å; P193-I205 VanDerWaalsContact CB-CG2 3.46Å; P193-I205 HydrophobicContact CG-CG2 4.28Å; P193-Y229 HydrophobicContact CB-CE1 3.67Å; P193-Y229 WeakPolarHBondContact CD-O 3.48Å; P193-Y229 HydrophobicContact CG-CD1 4Å; P193-Y229 HydrophobicContact CG-CE1 3.58Å; P193-Y229 WeakPolarHBondContact CG-O 3.41Å
194	S	67.5	Low	75.4	Confident	44 Å²	44	46.2 Å²	46.2	31%	0.308	27%	0.271	S	S	.	.	G	3₁₀ helix	trans	-64.1	-15.1	176.6	-31.9	0	0	0	0	113.1	N192 T197 Q213	N192-S194 PolarHBondContact O-N 3.21Å; N192-S194 VanDerWaalsContact O-N 3.1Å; N192-S194 WeakPolarHBondContact OD1-CA 3.35Å; N192-S194 WeakPolarHBondContact OD1-CB 3.43Å; N192-S194 PolarHBondContact OD1-N 3.35Å; N192-S194 PolarHBondContact OD1-OG 3.4Å; S194-T197 VanDerWaalsContact O-CG2 3.29Å; S194-T197 WeakPolarHBondContact O-CG2 3.5Å; S194-Q213 PolarHBondContact OG-NE2 3.27Å
195	S	65.6	Low	74.4	Confident	43 Å²	43	47 Å²	47	30%	0.301	28%	0.275	S	S	.	.	G	3₁₀ helix	trans	-89.2	-12.3	171.9	73	0	0	0	0	113.8	V189 N192 P193 T197	V189-S195 WeakPolarHBondContact CA-OG 3.32Å; N192-S195 WeakPolarHBondContact O-CB 3.49Å; N192-S195 PolarHBondContact O-N 3.18Å; N192-S195 PolarHBondContact O-OG 2.76Å; P193-S195 PolarHBondContact O-N 2.99Å; P193-S195 VanDerWaalsContact O-N 3.12Å; S195-T197 VanDerWaalsContact C-N 3.28Å; S195-T197 PolarHBondContact O-N 3Å
196	Q	67.8	Low	73.7	Confident	3 Å²	3	44.9 Å²	44.9	1%	0.014	27%	0.27	C	S	.	.			trans	-88.1	13.6	177.3	-58.5	-170	36.8	0	0	112.8	Y125 N126 V189 P193 S198 T199 G202	Y125-Q196 VanDerWaalsContact CD2-OE1 3.23Å; N126-Q196 PolarHBondContact O-NE2 2.76Å; V189-Q196 HydrophobicContact CG1-CG 3.65Å; V189-Q196 PolarHBondContact O-NE2 2.74Å; P193-Q196 WeakPolarHBondContact O-CB 3.27Å; P193-Q196 PolarHBondContact O-N 3.29Å; Q196-S198 PolarHBondContact O-N 3.15Å; Q196-T199 HydrophobicContact CB-CG2 4.31Å; Q196-T199 WeakPolarHBondContact O-CB 3.36Å; Q196-T199 WeakPolarHBondContact O-CG2 3.44Å; Q196-T199 PolarHBondContact O-N 2.67Å; Q196-T199 PolarHBondContact O-OG1 2.66Å; Q196-G202 WeakPolarHBondContact O-CA 2.91Å
197	T	60.8	Low	73.1	Confident	89 Å²	89	46 Å²	46	55%	0.546	28%	0.283	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.7	-15.6	-173.7	43.7	0	0	0	0	115.3	S194 S195	S194-T197 VanDerWaalsContact O-CG2 3.29Å; S194-T197 WeakPolarHBondContact O-CG2 3.5Å; S195-T197 VanDerWaalsContact C-N 3.28Å; S195-T197 PolarHBondContact O-N 3Å
198	S	61.3	Low	72.5	Confident	116 Å²	116	50.9 Å²	50.9	81%	0.811	31%	0.309	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.6	-8.4	172.6	53.1	0	0	0	0	114.4	Q196	Q196-S198 PolarHBondContact O-N 3.15Å
199	T	66.1	Low	72	Confident	34 Å²	34	48 Å²	48	21%	0.209	30%	0.295	C	S	.	.	S	Bend	trans	-85.5	158.4	176.2	69.1	0	0	0	0	111.7	Q196 Y201 G202	Q196-T199 HydrophobicContact CB-CG2 4.31Å; Q196-T199 WeakPolarHBondContact O-CB 3.36Å; Q196-T199 WeakPolarHBondContact O-CG2 3.44Å; Q196-T199 PolarHBondContact O-N 2.67Å; Q196-T199 PolarHBondContact O-OG1 2.66Å; T199-Y201 PolarHBondContact O-N 2.88Å; T199-Y201 VanDerWaalsContact O-N 3.1Å; T199-G202 PolarHBondContact O-N 2.96Å; T199-G202 PolarHBondContact OG1-N 3.24Å; T199-G202 VanDerWaalsContact OG1-N 3.14Å
200	V	65.6	Low	71.6	Confident	97 Å²	97	48.6 Å²	48.6	59%	0.588	30%	0.303	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.3	-28	179.7	-176.2	0	0	0	0	112.9
201	Y	67.1	Low	71.3	Confident	66 Å²	66	51.3 Å²	51.3	26%	0.259	32%	0.32	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.3	-13.2	179.4	-58.2	-74.1	0	0	0	113.4	I121 T199 S203 Q204 I205	I121-Y201 HydrophobicContact CG2-CE1 4.23Å; I121-Y201 HydrophobicContact CG2-CE2 4.14Å; I121-Y201 VanDerWaalsContact CG2-OH 3.24Å; I121-Y201 WeakPolarHBondContact CG2-OH 3.07Å; T199-Y201 PolarHBondContact O-N 2.88Å; T199-Y201 VanDerWaalsContact O-N 3.1Å; Y201-S203 VanDerWaalsContact C-N 3.3Å; Y201-S203 PolarHBondContact O-N 3.01Å; Y201-Q204 WeakPolarHBondContact O-CA 3.24Å; Y201-Q204 WeakPolarHBondContact O-CB 3.3Å; Y201-Q204 PolarHBondContact O-N 2.68Å; Y201-I205 WeakPolarHBondContact O-CD1 3.22Å; Y201-I205 WeakPolarHBondContact O-CG1 3.44Å; Y201-I205 PolarHBondContact O-N 2.78Å
202	G	69.8	Low	70.9	Confident	0 Å²	0	52.8 Å²	52.8	0%	0	33%	0.326	C	S	.	.	H	α-helix	trans	-57.6	-36.9	-172.7	0	0	0	0	0	114.3	Q196 T199 A206	Q196-G202 WeakPolarHBondContact O-CA 2.91Å; T199-G202 PolarHBondContact O-N 2.96Å; T199-G202 PolarHBondContact OG1-N 3.24Å; T199-G202 VanDerWaalsContact OG1-N 3.14Å; G202-A206 WeakPolarHBondContact O-CB 3.4Å; G202-A206 PolarHBondContact O-N 2.91Å
203	S	71.6	Confident	70.5	Confident	86 Å²	86	56.1 Å²	56.1	60%	0.601	34%	0.34	S	S	*	.	H	α-helix	trans	-69.8	-34.4	175.1	56.3	0	0	0	0	113.3	Y201 A207	Y201-S203 VanDerWaalsContact C-N 3.3Å; Y201-S203 PolarHBondContact O-N 3.01Å; S203-A207 PolarHBondContact O-N 3.34Å; S203-A207 VanDerWaalsContact O-N 3.16Å
204	Q	74.3	Confident	70.2	Confident	113 Å²	113	63.3 Å²	63.3	53%	0.528	37%	0.373	S	S	.	.	H	α-helix	trans	-71.8	-43.5	177.8	-56.1	177	6.6	0	0	110.4	Y201 A207 L208	Y201-Q204 WeakPolarHBondContact O-CA 3.24Å; Y201-Q204 WeakPolarHBondContact O-CB 3.3Å; Y201-Q204 PolarHBondContact O-N 2.68Å; Q204-A207 PolarHBondContact O-N 3.2Å; Q204-L208 WeakPolarHBondContact O-CG 3.07Å; Q204-L208 PolarHBondContact O-N 3.19Å; Q204-L208 VanDerWaalsContact O-N 3.13Å
205	I	72.6	Confident	69.7	Low	18 Å²	18	71 Å²	71	9%	0.092	40%	0.404	C	S	.	.	H	α-helix	trans	-69.5	-38.9	178.2	-53.6	152.8	0	0	0	110.5	Y125 P193 Y201 A207 L208 C209 Y229	Y125-I205 HydrophobicContact CD2-CD1 3.7Å; Y125-I205 HydrophobicContact CE2-CD1 3.44Å; Y125-I205 VanDerWaalsContact CE2-CD1 3.44Å; P193-I205 HydrophobicContact CB-CG2 3.46Å; P193-I205 VanDerWaalsContact CB-CG2 3.46Å; P193-I205 HydrophobicContact CG-CG2 4.28Å; Y201-I205 WeakPolarHBondContact O-CD1 3.22Å; Y201-I205 WeakPolarHBondContact O-CG1 3.44Å; Y201-I205 PolarHBondContact O-N 2.78Å; I205-A207 VanDerWaalsContact C-N 3.29Å; I205-A207 PolarHBondContact O-N 3.19Å; I205-L208 CarbonylContact O-C 3.6Å; I205-L208 WeakPolarHBondContact O-CB 3.45Å; I205-L208 PolarHBondContact O-N 3.09Å; I205-L208 VanDerWaalsContact O-N 3.09Å; I205-C209 PolarHBondContact O-N 2.94Å; I205-Y229 HydrophobicContact CG2-CE1 4.07Å
206	A	75.2	Confident	69.1	Low	37 Å²	37	77.4 Å²	77.4	31%	0.306	43%	0.43	S	S	.	.	H	α-helix	trans	-59.1	-39.2	172.7	0	0	0	0	0	112.2	G202 L208 C209 A210	G202-A206 WeakPolarHBondContact O-CB 3.4Å; G202-A206 PolarHBondContact O-N 2.91Å; A206-L208 VanDerWaalsContact C-N 3.35Å; A206-C209 PolarHBondContact O-N 3.48Å; A206-A210 WeakPolarHBondContact O-CB 3.5Å; A206-A210 PolarHBondContact O-N 3Å
207	A	76.1	Confident	68.4	Low	69 Å²	69	80.3 Å²	80.3	57%	0.57	45%	0.447	S	S	*	.	H	α-helix	trans	-66.4	-34.1	174.2	0	0	0	0	0	113	S203 Q204 I205 P211	S203-A207 PolarHBondContact O-N 3.34Å; S203-A207 VanDerWaalsContact O-N 3.16Å; Q204-A207 PolarHBondContact O-N 3.2Å; I205-A207 VanDerWaalsContact C-N 3.29Å; I205-A207 PolarHBondContact O-N 3.19Å; A207-P211 WeakPolarHBondContact O-CD 3.45Å
208	L	75.9	Confident	68	Low	103 Å²	103	82.6 Å²	82.6	54%	0.539	47%	0.467	S	S	.	.	H	α-helix	trans	-72.1	-30.1	173.3	-67.3	171.2	0	0	0	112.9	Q204 I205 A206 P211 Y212	Q204-L208 WeakPolarHBondContact O-CG 3.07Å; Q204-L208 PolarHBondContact O-N 3.19Å; Q204-L208 VanDerWaalsContact O-N 3.13Å; I205-L208 CarbonylContact O-C 3.6Å; I205-L208 WeakPolarHBondContact O-CB 3.45Å; I205-L208 PolarHBondContact O-N 3.09Å; I205-L208 VanDerWaalsContact O-N 3.09Å; A206-L208 VanDerWaalsContact C-N 3.35Å; L208-P211 WeakPolarHBondContact O-CD 3.4Å; L208-P211 WeakPolarHBondContact O-CG 3.38Å; L208-Y212 WeakPolarHBondContact O-CD2 3.4Å; L208-Y212 WeakPolarHBondContact O-CE2 3.44Å
209	C	78.5	Confident	67.5	Low	1 Å²	1	78.9 Å²	78.9	1%	0.007	45%	0.447	C	S	.	.	H	α-helix	trans	-86.6	-25.4	178	-70.1	0	0	0	0	114.7	I205 A206 P211 Y212 Q213 C230	I205-C209 PolarHBondContact O-N 2.94Å; A206-C209 PolarHBondContact O-N 3.48Å; C209-P211 VanDerWaalsContact C-CD 3.48Å; C209-Y212 PolarHBondContact O-N 3.22Å; C209-Q213 PolarHBondContact O-N 2.84Å; C209-C230 WeakPolarHBondContact CA-SG 3.38Å; C209-C230 HydrophobicContact CB-CB 3.57Å; C209-C230 WeakPolarHBondContact CB-SG 3.3Å; C209-C230 VanDerWaalsContact SG-CA 3.6Å; C209-C230 WeakPolarHBondContact SG-CB 3.33Å; C209-C230 CovalentContact SG-SG 2.04Å; C209-C230 PolarHBondContact SG-SG 2.75Å
210	A	76.8	Confident	66.9	Low	48 Å²	48	85.1 Å²	85.1	40%	0.397	48%	0.478	S	S	.	.	H	α-helix	trans	-45.8	-46.4	176.7	0	0	0	0	0	115.2	A206 Y212 Q213	A206-A210 WeakPolarHBondContact O-CB 3.5Å; A206-A210 PolarHBondContact O-N 3Å; A210-Y212 VanDerWaalsContact C-N 3.29Å; A210-Y212 PolarHBondContact O-N 2.86Å; A210-Q213 PolarHBondContact O-N 3.23Å
211	P	74.3	Confident	66.4	Low	56 Å²	56	89.5 Å²	89.5	36%	0.364	49%	0.489	S	S	.	.	H	α-helix	trans	-62.1	-32	176.6	22.7	-34.3	0	0	0	113.6	A207 L208 C209 V217	A207-P211 WeakPolarHBondContact O-CD 3.45Å; L208-P211 WeakPolarHBondContact O-CD 3.4Å; L208-P211 WeakPolarHBondContact O-CG 3.38Å; C209-P211 VanDerWaalsContact C-CD 3.48Å; P211-V217 HydrophobicContact CB-CG2 3.97Å; P211-V217 WeakPolarHBondContact O-CG2 3.48Å
212	Y	72.7	Confident	66.1	Low	39 Å²	39	90.6 Å²	90.6	15%	0.153	50%	0.497	C	S	.	.	H	α-helix	trans	-81.7	-15.3	-179.2	-58	-71.8	0	0	0	113.7	L208 C209 A210 Q222 L226 Y227 C230	L208-Y212 WeakPolarHBondContact O-CD2 3.4Å; L208-Y212 WeakPolarHBondContact O-CE2 3.44Å; C209-Y212 PolarHBondContact O-N 3.22Å; A210-Y212 VanDerWaalsContact C-N 3.29Å; A210-Y212 PolarHBondContact O-N 2.86Å; Y212-Q222 HydrophobicContact CE1-CG 3.78Å; Y212-L226 HydrophobicContact CD2-CG 4.42Å; Y212-L226 HydrophobicContact CE2-CB 4.36Å; Y212-L226 HydrophobicContact CE2-CD2 3.66Å; Y212-L226 HydrophobicContact CE2-CG 3.7Å; Y212-Y227 AromaticContact CD1-CD2 3.94Å; Y212-Y227 HydrophobicContact CD1-CD2 3.94Å; Y212-C230 HydrophobicContact CD2-CB 4.18Å; Y212-C230 HydrophobicContact CG-CB 4.44Å
213	Q	70.1	Confident	66.1	Low	115 Å²	115	95 Å²	95	54%	0.537	52%	0.52	S	S	.	.	H	α-helix	trans	-86.4	-14	176.9	-68.3	-179.6	-7.6	0	0	113.1	S194 C209 A210	S194-Q213 PolarHBondContact OG-NE2 3.27Å; C209-Q213 PolarHBondContact O-N 2.84Å; A210-Q213 PolarHBondContact O-N 3.23Å
214	Q	64.3	Low	66	Low	152 Å²	152	96 Å²	96	71%	0.71	52%	0.515	S	S	*	.	S	Bend	trans	-103.3	140.3	172.6	-63.1	-167.1	-3.1	0	0	110.7	Q216	Q214-Q216 PolarHBondContact O-N 3.42Å
215	Q	58.1	Low	65.9	Low	205 Å²	205	94.3 Å²	94.3	96%	0.958	51%	0.505	S	S	*	.	S	Bend	trans	-72	18.6	-171.9	-62.2	178.9	-54.8	0	0	115
216	Q	51.8	Low	65.8	Low	179 Å²	179	95.4 Å²	95.4	84%	0.836	51%	0.51	S	S	*	.			trans	-131.2	58.6	-170.7	-66.9	-160.3	-11.2	0	0	113.9	Q214	Q214-Q216 PolarHBondContact O-N 3.42Å
217	V	53.3	Low	65.7	Low	63 Å²	63	98.5 Å²	98.5	38%	0.382	52%	0.515	S	S	.	.			trans	-125.7	76	166.8	-172.5	0	0	0	0	110.5	P211 G219	P211-V217 HydrophobicContact CB-CG2 3.97Å; P211-V217 WeakPolarHBondContact O-CG2 3.48Å; V217-G219 PolarHBondContact O-N 3.17Å
218	S	51.6	Low	65.6	Low	137 Å²	137	96.5 Å²	96.5	96%	0.958	49%	0.494	S	S	*	.			trans	-80.4	85.2	167.7	-53.8	0	0	0	0	109.5
219	G	52	Low	65.5	Low	39 Å²	39	92.1 Å²	92.1	40%	0.402	47%	0.47	S	S	.	.			trans	-136.3	130.1	-174.8	0	0	0	0	0	113.5	V217 F221 Q222	V217-G219 PolarHBondContact O-N 3.17Å; G219-F221 PolarHBondContact O-N 2.91Å; G219-F221 VanDerWaalsContact O-N 3.12Å; G219-Q222 PolarHBondContact O-N 3.07Å
220	I	54.1	Low	65.5	Low	165 Å²	165	92.4 Å²	92.4	85%	0.846	47%	0.472	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.3	-12.5	-173.1	-70.3	166.5	0	0	0	113.7
221	F	54.4	Low	65.6	Low	189 Å²	189	92.6 Å²	92.6	83%	0.829	47%	0.468	S	S	*	.	T	Hydrogen-bonded Turn	trans	-116.1	51.1	178.5	-62.3	-74.4	0	0	0	112.3	G219 N223	G219-F221 PolarHBondContact O-N 2.91Å; G219-F221 VanDerWaalsContact O-N 3.12Å; F221-N223 PolarHBondContact O-N 3.02Å
222	Q	61.7	Low	65.9	Low	89 Å²	89	92.5 Å²	92.5	42%	0.416	47%	0.466	S	S	.	.			trans	-74.9	118	175.9	-155	174	-9.9	0	0	110.4	Y212 G219 Q224	Y212-Q222 HydrophobicContact CE1-CG 3.78Å; G219-Q222 PolarHBondContact O-N 3.07Å; Q222-Q224 PolarHBondContact O-N 3.13Å
223	N	68.1	Low	66.4	Low	93 Å²	93	92.1 Å²	92.1	50%	0.497	47%	0.466	S	S	.	.			trans	-72	100	178.3	-86.7	-79.8	0	0	0	109.7	F221 Y225 L226 Y227	F221-N223 PolarHBondContact O-N 3.02Å; N223-Y225 VanDerWaalsContact C-N 3.32Å; N223-Y225 PolarHBondContact O-N 2.77Å; N223-L226 HydrophobicContact CB-CB 3.81Å; N223-L226 WeakPolarHBondContact O-CA 2.98Å; N223-L226 PolarHBondContact O-N 3.45Å; N223-Y227 PolarHBondContact O-N 2.88Å
224	Q	69.3	Low	67.1	Low	105 Å²	105	91.1 Å²	91.1	49%	0.491	47%	0.469	S	S	.	.	H	α-helix	trans	-51.6	-47.6	-175.2	-177.9	175.9	-7.2	0	0	112.7	Q222 L226 Y227 H228	Q222-Q224 PolarHBondContact O-N 3.13Å; Q224-L226 VanDerWaalsContact C-N 3.33Å; Q224-L226 PolarHBondContact O-N 2.86Å; Q224-Y227 WeakPolarHBondContact O-CB 3.18Å; Q224-Y227 PolarHBondContact O-N 3.35Å; Q224-H228 WeakPolarHBondContact CG-NE2 3.37Å; Q224-H228 PolarHBondContact NE2-NE2 3.38Å; Q224-H228 PolarHBondContact O-CD2 2.68Å; Q224-H228 PolarHBondContact O-N 3.12Å
225	Y	72.2	Confident	68.1	Low	79 Å²	79	87.5 Å²	87.5	31%	0.31	45%	0.453	S	S	.	.	H	α-helix	trans	-56.4	-43.5	174.7	170.9	-110.7	0	0	0	112.9	A75 P128 N223 Y227 H228 Y229	A75-Y225 HydrophobicContact CB-CD1 3.91Å; A75-Y225 HydrophobicContact CB-CD2 3.48Å; A75-Y225 VanDerWaalsContact CB-CD2 3.48Å; A75-Y225 HydrophobicContact CB-CE1 4.26Å; A75-Y225 HydrophobicContact CB-CE2 3.85Å; A75-Y225 HydrophobicContact CB-CG 3.48Å; A75-Y225 VanDerWaalsContact CB-CG 3.48Å; P128-Y225 WeakPolarHBondContact CG-OH 3.13Å; N223-Y225 VanDerWaalsContact C-N 3.32Å; N223-Y225 PolarHBondContact O-N 2.77Å; Y225-Y227 VanDerWaalsContact C-N 3.32Å; Y225-Y227 PolarHBondContact O-N 2.93Å; Y225-H228 PolarHBondContact O-N 2.92Å; Y225-Y229 VanDerWaalsContact O-CB 3.28Å; Y225-Y229 WeakPolarHBondContact O-CB 3.38Å; Y225-Y229 PolarHBondContact O-N 3.42Å
226	L	71.2	Confident	69.5	Low	40 Å²	40	78.1 Å²	78.1	21%	0.209	41%	0.409	C	S	.	.	H	α-helix	trans	-70.9	-29.8	-179.1	-167.5	60	0	0	0	111.9	Y212 N223 Q224 Y229 C230	Y212-L226 HydrophobicContact CD2-CG 4.42Å; Y212-L226 HydrophobicContact CE2-CB 4.36Å; Y212-L226 HydrophobicContact CE2-CD2 3.66Å; Y212-L226 HydrophobicContact CE2-CG 3.7Å; N223-L226 HydrophobicContact CB-CB 3.81Å; N223-L226 WeakPolarHBondContact O-CA 2.98Å; N223-L226 PolarHBondContact O-N 3.45Å; Q224-L226 VanDerWaalsContact C-N 3.33Å; Q224-L226 PolarHBondContact O-N 2.86Å; L226-Y229 HydrophobicContact CD1-CD1 4.44Å; L226-C230 VanDerWaalsContact O-CB 3.25Å; L226-C230 WeakPolarHBondContact O-CB 3.4Å; L226-C230 PolarHBondContact O-N 3.43Å; L226-C230 PolarHBondContact O-SG 3.05Å
227	Y	74.2	Confident	71.2	Confident	102 Å²	102	71.7 Å²	71.7	40%	0.4	39%	0.386	S	S	.	.	H	α-helix	trans	-66	-52.5	170.8	179.6	-103.9	0	0	0	111.8	Y212 N223 Q224 Y225 Y229 C230 V231	Y212-Y227 AromaticContact CD1-CD2 3.94Å; Y212-Y227 HydrophobicContact CD1-CD2 3.94Å; N223-Y227 PolarHBondContact O-N 2.88Å; Q224-Y227 WeakPolarHBondContact O-CB 3.18Å; Q224-Y227 PolarHBondContact O-N 3.35Å; Y225-Y227 VanDerWaalsContact C-N 3.32Å; Y225-Y227 PolarHBondContact O-N 2.93Å; Y227-Y229 PolarHBondContact O-N 3.37Å; Y227-C230 PolarHBondContact O-N 3.01Å; Y227-V231 HydrophobicContact CD2-CG2 4.09Å; Y227-V231 HydrophobicContact CE2-CG2 3.88Å; Y227-V231 WeakPolarHBondContact O-CB 3.01Å; Y227-V231 PolarHBondContact O-N 2.78Å
228	H	72.6	Confident	73	Confident	27 Å²	27	72.4 Å²	72.4	13%	0.125	39%	0.387	C	S	.	.	H	α-helix	trans	-62.7	-27.3	175.9	-64.9	-79.9	0	0	0	112.7	Y71 Q224 Y225 E233	Y71-H228 AromaticContact CD1-CD2 3.87Å; Y71-H228 AromaticContact CD1-CE1 3.93Å; Y71-H228 AromaticContact CD1-NE2 3.47Å; Y71-H228 WeakPolarHBondContact CD1-NE2 3.37Å; Y71-H228 AromaticContact CD2-CE1 3.81Å; Y71-H228 AromaticContact CD2-ND1 3.79Å; Y71-H228 AromaticContact CE1-CE1 3.73Å; Y71-H228 AromaticContact CE1-NE2 3.56Å; Y71-H228 AromaticContact CE2-CE1 3.59Å; Y71-H228 AromaticContact CE2-ND1 3.84Å; Y71-H228 AromaticContact CG-CD2 3.73Å; Y71-H228 AromaticContact CG-CE1 3.97Å; Y71-H228 AromaticContact CG-NE2 3.73Å; Y71-H228 AromaticContact CZ-CE1 3.54Å; Y71-H228 AromaticContact CZ-NE2 3.89Å; Q224-H228 WeakPolarHBondContact CG-NE2 3.37Å; Q224-H228 PolarHBondContact NE2-NE2 3.38Å; Q224-H228 PolarHBondContact O-CD2 2.68Å; Q224-H228 PolarHBondContact O-N 3.12Å; Y225-H228 PolarHBondContact O-N 2.92Å; H228-E233 IonicContact CE1-OE1 2.77Å; H228-E233 PolarHBondContact CE1-OE1 3.45Å; H228-E233 VanDerWaalsContact CE1-OE1 3.24Å; H228-E233 IonicContact ND1-OE1 2.8Å; H228-E233 PolarHBondContact ND1-OE1 3.1Å
229	Y	75.1	Confident	74.9	Confident	12 Å²	12	66 Å²	66	5%	0.047	34%	0.342	C	S	.	.	H	α-helix	trans	-80.2	-32.2	176.9	-174.5	-114.4	0	0	0	113.9	Y125 P128 A190 P193 I205 Y225 L226 Y227	Y125-Y229 WeakPolarHBondContact OH-CE1 3.43Å; Y125-Y229 VanDerWaalsContact OH-CZ 3.26Å; Y125-Y229 PolarHBondContact OH-OH 3.13Å; P128-Y229 HydrophobicContact CB-CD2 4.02Å; P128-Y229 HydrophobicContact CB-CE2 3.83Å; P128-Y229 HydrophobicContact CG-CD2 3.84Å; P128-Y229 HydrophobicContact CG-CE2 3.68Å; A190-Y229 WeakPolarHBondContact O-CE2 3.46Å; P193-Y229 HydrophobicContact CB-CE1 3.67Å; P193-Y229 WeakPolarHBondContact CD-O 3.48Å; P193-Y229 HydrophobicContact CG-CD1 4Å; P193-Y229 HydrophobicContact CG-CE1 3.58Å; P193-Y229 WeakPolarHBondContact CG-O 3.41Å; I205-Y229 HydrophobicContact CG2-CE1 4.07Å; Y225-Y229 VanDerWaalsContact O-CB 3.28Å; Y225-Y229 WeakPolarHBondContact O-CB 3.38Å; Y225-Y229 PolarHBondContact O-N 3.42Å; L226-Y229 HydrophobicContact CD1-CD1 4.44Å; Y227-Y229 PolarHBondContact O-N 3.37Å
230	C	77.9	Confident	76.8	Confident	7 Å²	7	64.9 Å²	64.9	5%	0.047	33%	0.328	C	S	.	.	H	α-helix	trans	-91	-18.2	-179.8	-68.7	0	0	0	0	113.8	C209 Y212 L226 Y227	C209-C230 WeakPolarHBondContact CA-SG 3.38Å; C209-C230 HydrophobicContact CB-CB 3.57Å; C209-C230 WeakPolarHBondContact CB-SG 3.3Å; C209-C230 VanDerWaalsContact SG-CA 3.6Å; C209-C230 WeakPolarHBondContact SG-CB 3.33Å; C209-C230 CovalentContact SG-SG 2.04Å; C209-C230 PolarHBondContact SG-SG 2.75Å; Y212-C230 HydrophobicContact CD2-CB 4.18Å; Y212-C230 HydrophobicContact CG-CB 4.44Å; L226-C230 VanDerWaalsContact O-CB 3.25Å; L226-C230 WeakPolarHBondContact O-CB 3.4Å; L226-C230 PolarHBondContact O-N 3.43Å; L226-C230 PolarHBondContact O-SG 3.05Å; Y227-C230 PolarHBondContact O-N 3.01Å
231	V	78.6	Confident	78.8	Confident	51 Å²	51	61 Å²	61	31%	0.309	31%	0.312	S	S	.	.	S	Bend	trans	-119.4	100.4	179.1	-176.5	0	0	0	0	108.9	Y227 E233	Y227-V231 HydrophobicContact CD2-CG2 4.09Å; Y227-V231 HydrophobicContact CE2-CG2 3.88Å; Y227-V231 WeakPolarHBondContact O-CB 3.01Å; Y227-V231 PolarHBondContact O-N 2.78Å; V231-E233 PolarHBondContact O-N 3.13Å
232	V	80.5	Confident	80.7	Confident	54 Å²	54	54.8 Å²	54.8	33%	0.327	28%	0.284	S	S	.	.			trans	-56	120	-179.6	179.3	0	0	0	0	110.4	I191 N192 E236 A237	I191-V232 HydrophobicContact CD1-CG1 4.03Å; N192-V232 HydrophobicContact CB-CG2 3.85Å; V232-E236 HydrophobicContact CG1-CB 4.38Å; V232-A237 HydrophobicContact CG1-CB 4.42Å
233	E	83.1	Confident	82.1	Confident	31 Å²	31	50.5 Å²	50.5	15%	0.145	26%	0.264	C	S	.	.			trans	-70.7	151.1	-179.4	-70.2	-155.2	150.7	0	0	112.2	H228 V231 Q235 E236 A237	H228-E233 IonicContact CE1-OE1 2.77Å; H228-E233 PolarHBondContact CE1-OE1 3.45Å; H228-E233 VanDerWaalsContact CE1-OE1 3.24Å; H228-E233 IonicContact ND1-OE1 2.8Å; H228-E233 PolarHBondContact ND1-OE1 3.1Å; V231-E233 PolarHBondContact O-N 3.13Å; E233-Q235 PolarHBondContact O-N 3.11Å; E233-Q235 VanDerWaalsContact O-N 3.16Å; E233-E236 HydrophobicContact CB-CG 4.25Å; E233-E236 PolarHBondContact O-N 3.15Å; E233-E236 VanDerWaalsContact O-N 3.11Å; E233-A237 PolarHBondContact O-N 3.49Å
234	P	85.8	Confident	83.4	Confident	94 Å²	94	50.3 Å²	50.3	61%	0.61	26%	0.259	S	S	*	.	H	α-helix	trans	-57.9	-29.7	171.8	24.5	-34.3	0	0	0	112.2	I238	P234-I238 VanDerWaalsContact O-CB 3.3Å; P234-I238 WeakPolarHBondContact O-CB 3.26Å; P234-I238 VanDerWaalsContact O-CD1 3.32Å; P234-I238 WeakPolarHBondContact O-CD1 3.47Å; P234-I238 WeakPolarHBondContact O-CG1 3.49Å; P234-I238 PolarHBondContact O-N 2.83Å
235	Q	84.3	Confident	84.7	Confident	77 Å²	77	49.5 Å²	49.5	36%	0.36	26%	0.258	S	S	.	.	H	α-helix	trans	-66.9	-42.4	177.1	-57.1	-173.8	20.5	0	0	111.9	S67 T68 E233 I238 A239	S67-Q235 PolarHBondContact OG-OE1 3.06Å; T68-Q235 HydrophobicContact CG2-CB 3.99Å; E233-Q235 PolarHBondContact O-N 3.11Å; E233-Q235 VanDerWaalsContact O-N 3.16Å; Q235-I238 PolarHBondContact O-N 3.26Å; Q235-A239 PolarHBondContact O-N 3.32Å
236	E	87.1	Confident	85.7	Confident	7 Å²	7	45.8 Å²	45.8	3%	0.033	24%	0.243	C	C	.	.	H	α-helix	trans	-71.2	-40.4	177.4	-60.5	-173.8	141.6	0	0	111.6	T68 K132 Y187 I191 V232 E233 I238 A239 V240	T68-E236 HydrophobicContact CG2-CG 3.5Å; T68-E236 VanDerWaalsContact CG2-CG 3.5Å; K132-E236 WeakPolarHBondContact CE-OE1 3.49Å; K132-E236 IonicContact NZ-OE1 3.41Å; K132-E236 PolarHBondContact NZ-OE1 2.78Å; Y187-E236 WeakPolarHBondContact OH-CA 3.5Å; Y187-E236 VanDerWaalsContact OH-CB 3.3Å; Y187-E236 WeakPolarHBondContact OH-CB 3.34Å; Y187-E236 WeakPolarHBondContact OH-CG 3.48Å; I191-E236 HydrophobicContact CD1-CB 3.77Å; I191-E236 HydrophobicContact CG2-CB 4.35Å; I191-E236 HydrophobicContact CG2-CG 4.38Å; V232-E236 HydrophobicContact CG1-CB 4.38Å; E233-E236 HydrophobicContact CB-CG 4.25Å; E233-E236 PolarHBondContact O-N 3.15Å; E233-E236 VanDerWaalsContact O-N 3.11Å; E236-I238 VanDerWaalsContact C-N 3.34Å; E236-I238 PolarHBondContact O-N 2.96Å; E236-A239 WeakPolarHBondContact O-CB 3.41Å; E236-A239 PolarHBondContact O-N 2.81Å; E236-V240 WeakPolarHBondContact O-CG2 3.18Å; E236-V240 PolarHBondContact O-N 3.1Å
237	A	89	Confident	86.8	Confident	44 Å²	44	44.2 Å²	44.2	36%	0.364	24%	0.235	S	C	.	.	H	α-helix	trans	-60.7	-41.5	173.3	0	0	0	0	0	112.2	V232 E233 V240 V241	V232-A237 HydrophobicContact CG1-CB 4.42Å; E233-A237 PolarHBondContact O-N 3.49Å; A237-V240 PolarHBondContact O-N 3.4Å; A237-V241 WeakPolarHBondContact O-CG2 3.21Å; A237-V241 PolarHBondContact O-N 2.92Å
238	I	91.1	Very high	87.8	Confident	79 Å²	79	41.3 Å²	41.3	41%	0.405	23%	0.232	S	C	.	.	H	α-helix	trans	-62.9	-42.1	173.7	-74.8	164.9	0	0	0	111	P234 Q235 E236 V240 V241 F242	P234-I238 VanDerWaalsContact O-CB 3.3Å; P234-I238 WeakPolarHBondContact O-CB 3.26Å; P234-I238 VanDerWaalsContact O-CD1 3.32Å; P234-I238 WeakPolarHBondContact O-CD1 3.47Å; P234-I238 WeakPolarHBondContact O-CG1 3.49Å; P234-I238 PolarHBondContact O-N 2.83Å; Q235-I238 PolarHBondContact O-N 3.26Å; E236-I238 VanDerWaalsContact C-N 3.34Å; E236-I238 PolarHBondContact O-N 2.96Å; I238-V240 PolarHBondContact O-N 3.21Å; I238-V241 PolarHBondContact O-N 3.2Å; I238-F242 HydrophobicContact CG2-CD2 3.68Å; I238-F242 HydrophobicContact CG2-CE1 4.27Å; I238-F242 HydrophobicContact CG2-CE2 3.23Å; I238-F242 HydrophobicContact CG2-CG 4.37Å; I238-F242 HydrophobicContact CG2-CZ 3.58Å; I238-F242 WeakPolarHBondContact O-CG 3.36Å; I238-F242 PolarHBondContact O-N 3.12Å
239	A	91.3	Very high	88.7	Confident	2 Å²	2	40.2 Å²	40.2	2%	0.017	23%	0.228	C	C	.	.	H	α-helix	trans	-62.3	-39.4	175.8	0	0	0	0	0	112.7	C64 V65 Y187 Q235 E236 G243	C64-A239 HydrophobicContact CB-CB 3.88Å; V65-A239 HydrophobicContact CG2-CB 3.94Å; Y187-A239 HydrophobicContact CE1-CB 3.8Å; Q235-A239 PolarHBondContact O-N 3.32Å; E236-A239 WeakPolarHBondContact O-CB 3.41Å; E236-A239 PolarHBondContact O-N 2.81Å; A239-G243 PolarHBondContact O-N 2.97Å
240	V	92.1	Very high	89.5	Confident	16 Å²	16	39.6 Å²	39.6	10%	0.097	23%	0.226	C	C	.	.	H	α-helix	trans	-60.9	-47.6	172.2	171.3	0	0	0	0	111.2	Y187 L188 I191 E236 A237 I238 G243 F244	Y187-V240 HydrophobicContact CD1-CG2 3.67Å; Y187-V240 HydrophobicContact CE1-CG2 3.72Å; L188-V240 HydrophobicContact CB-CG2 4.34Å; L188-V240 HydrophobicContact CD1-CG1 4.14Å; I191-V240 HydrophobicContact CD1-CG2 3.75Å; E236-V240 WeakPolarHBondContact O-CG2 3.18Å; E236-V240 PolarHBondContact O-N 3.1Å; A237-V240 PolarHBondContact O-N 3.4Å; I238-V240 PolarHBondContact O-N 3.21Å; V240-G243 PolarHBondContact O-N 3.46Å; V240-F244 HydrophobicContact CG1-CD2 3.86Å; V240-F244 HydrophobicContact CG1-CE2 3.55Å; V240-F244 VanDerWaalsContact O-CD2 3.28Å; V240-F244 WeakPolarHBondContact O-CD2 3.34Å; V240-F244 PolarHBondContact O-N 3.39Å; V240-F244 VanDerWaalsContact O-N 3.08Å
241	V	94.9	Very high	90.1	Very high	84 Å²	84	43.5 Å²	43.5	51%	0.509	25%	0.245	S	C	.	.	H	α-helix	trans	-61.8	-47	178.7	171.6	0	0	0	0	111.4	A237 I238 G243 F244 L245	A237-V241 WeakPolarHBondContact O-CG2 3.21Å; A237-V241 PolarHBondContact O-N 2.92Å; I238-V241 PolarHBondContact O-N 3.2Å; V241-G243 VanDerWaalsContact C-N 3.29Å; V241-G243 PolarHBondContact O-N 2.92Å; V241-F244 PolarHBondContact O-N 3.46Å; V241-L245 HydrophobicContact CG1-CD1 4.1Å; V241-L245 WeakPolarHBondContact O-CG 3.47Å; V241-L245 PolarHBondContact O-N 3.4Å
242	F	94.3	Very high	90.8	Very high	57 Å²	57	44.3 Å²	44.3	25%	0.25	25%	0.247	C	C	.	.	H	α-helix	trans	-61.6	-36.6	175.6	-68.2	-24.9	0	0	0	112.2	L57 A60 I61 I238 L245 V246	L57-F242 HydrophobicContact CD2-CB 4.04Å; L57-F242 HydrophobicContact CD2-CD1 3.51Å; L57-F242 HydrophobicContact CD2-CE1 4.1Å; L57-F242 HydrophobicContact CD2-CG 3.85Å; A60-F242 HydrophobicContact CB-CD2 3.82Å; A60-F242 HydrophobicContact CB-CE2 3.59Å; A60-F242 HydrophobicContact CB-CZ 4.41Å; I61-F242 HydrophobicContact CD1-CB 3.82Å; I61-F242 HydrophobicContact CG1-CB 3.43Å; I61-F242 VanDerWaalsContact CG1-CB 3.43Å; I61-F242 HydrophobicContact CG1-CD2 4.32Å; I61-F242 HydrophobicContact CG1-CG 4.39Å; I238-F242 HydrophobicContact CG2-CD2 3.68Å; I238-F242 HydrophobicContact CG2-CE1 4.27Å; I238-F242 HydrophobicContact CG2-CE2 3.23Å; I238-F242 HydrophobicContact CG2-CG 4.37Å; I238-F242 HydrophobicContact CG2-CZ 3.58Å; I238-F242 WeakPolarHBondContact O-CG 3.36Å; I238-F242 PolarHBondContact O-N 3.12Å; F242-L245 HydrophobicContact CD1-CD1 4.3Å; F242-L245 CarbonylContact O-C 3.48Å; F242-L245 PolarHBondContact O-N 3.37Å; F242-V246 WeakPolarHBondContact O-CG2 3.44Å; F242-V246 PolarHBondContact O-N 3.25Å
243	G	92.4	Very high	91.1	Very high	0 Å²	0	42 Å²	42	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-63.6	-41.1	175.9	0	0	0	0	0	113.6	T184 A239 V240 V241 L245 V246 T247	T184-G243 VanDerWaalsContact CG2-CA 3.48Å; A239-G243 PolarHBondContact O-N 2.97Å; V240-G243 PolarHBondContact O-N 3.46Å; V241-G243 VanDerWaalsContact C-N 3.29Å; V241-G243 PolarHBondContact O-N 2.92Å; G243-L245 VanDerWaalsContact C-N 3.34Å; G243-V246 PolarHBondContact O-N 2.71Å; G243-T247 PolarHBondContact O-N 3.16Å; G243-T247 PolarHBondContact O-OG1 3.48Å; G243-T247 VanDerWaalsContact O-OG1 3.06Å
244	F	95	Very high	91.5	Very high	89 Å²	89	42.5 Å²	42.5	39%	0.39	24%	0.236	S	C	.	.	H	α-helix	trans	-65.5	-37.1	171.1	-74.7	-61.8	0	0	0	112	V240 V241 T247 A248	V240-F244 HydrophobicContact CG1-CD2 3.86Å; V240-F244 HydrophobicContact CG1-CE2 3.55Å; V240-F244 VanDerWaalsContact O-CD2 3.28Å; V240-F244 WeakPolarHBondContact O-CD2 3.34Å; V240-F244 PolarHBondContact O-N 3.39Å; V240-F244 VanDerWaalsContact O-N 3.08Å; V241-F244 PolarHBondContact O-N 3.46Å; F244-T247 WeakPolarHBondContact O-CB 3.41Å; F244-T247 PolarHBondContact O-N 2.96Å; F244-A248 WeakPolarHBondContact O-CB 3.25Å; F244-A248 PolarHBondContact O-N 2.97Å
245	L	95.2	Very high	91.6	Very high	88 Å²	88	41 Å²	41	46%	0.461	23%	0.225	S	C	.	.	H	α-helix	trans	-66.9	-36	174.4	-69.4	171	0	0	0	112.9	L57 V241 F242 G243 A248 A249	L57-L245 HydrophobicContact CD1-CB 3.91Å; V241-L245 HydrophobicContact CG1-CD1 4.1Å; V241-L245 WeakPolarHBondContact O-CG 3.47Å; V241-L245 PolarHBondContact O-N 3.4Å; F242-L245 HydrophobicContact CD1-CD1 4.3Å; F242-L245 CarbonylContact O-C 3.48Å; F242-L245 PolarHBondContact O-N 3.37Å; G243-L245 VanDerWaalsContact C-N 3.34Å; L245-A248 PolarHBondContact O-N 3.42Å; L245-A249 VanDerWaalsContact O-CB 3.3Å; L245-A249 WeakPolarHBondContact O-CB 3.21Å; L245-A249 PolarHBondContact O-N 3.23Å
246	V	94.9	Very high	91.8	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-63.1	-44.1	170.9	164.4	0	0	0	0	110.9	T54 L57 I61 V142 M180 F242 G243 A248 A249 L250	T54-V246 HydrophobicContact CG2-CG1 4.17Å; L57-V246 HydrophobicContact CB-CG2 3.48Å; L57-V246 VanDerWaalsContact CB-CG2 3.48Å; L57-V246 HydrophobicContact CD1-CG2 4Å; L57-V246 HydrophobicContact CG-CG2 4.39Å; I61-V246 HydrophobicContact CD1-CG2 3.7Å; V142-V246 HydrophobicContact CG1-CG1 3.92Å; M180-V246 HydrophobicContact CE-CG1 4.05Å; M180-V246 HydrophobicContact CG-CG1 4.15Å; F242-V246 WeakPolarHBondContact O-CG2 3.44Å; F242-V246 PolarHBondContact O-N 3.25Å; G243-V246 PolarHBondContact O-N 2.71Å; V246-A248 PolarHBondContact O-N 3.36Å; V246-A249 PolarHBondContact O-N 3.17Å; V246-L250 HydrophobicContact CG1-CD1 3.87Å; V246-L250 HydrophobicContact CG1-CG 4.5Å; V246-L250 WeakPolarHBondContact O-CG 3.48Å; V246-L250 PolarHBondContact O-N 3.16Å
247	T	93.8	Very high	91.7	Very high	8 Å²	8	39.5 Å²	39.5	5%	0.049	22%	0.217	C	C	.	.	H	α-helix	trans	-61.1	-44.9	176.1	-60.5	0	0	0	0	111.2	L181 G243 F244 L250 I251	L181-T247 HydrophobicContact CB-CG2 3.99Å; L181-T247 HydrophobicContact CD1-CG2 4.18Å; G243-T247 PolarHBondContact O-N 3.16Å; G243-T247 PolarHBondContact O-OG1 3.48Å; G243-T247 VanDerWaalsContact O-OG1 3.06Å; F244-T247 WeakPolarHBondContact O-CB 3.41Å; F244-T247 PolarHBondContact O-N 2.96Å; T247-L250 PolarHBondContact O-N 3.41Å; T247-I251 HydrophobicContact CG2-CD1 4.16Å; T247-I251 WeakPolarHBondContact O-CG1 3.4Å; T247-I251 PolarHBondContact O-N 2.98Å
248	A	94	Very high	91.5	Very high	40 Å²	40	41 Å²	41	33%	0.331	22%	0.219	S	C	.	.	H	α-helix	trans	-62.9	-41.7	174.3	0	0	0	0	0	112.2	F244 L245 V246 L250 I251 I252	F244-A248 WeakPolarHBondContact O-CB 3.25Å; F244-A248 PolarHBondContact O-N 2.97Å; L245-A248 PolarHBondContact O-N 3.42Å; V246-A248 PolarHBondContact O-N 3.36Å; A248-L250 PolarHBondContact O-N 3.16Å; A248-I251 PolarHBondContact O-N 3.01Å; A248-I252 WeakPolarHBondContact O-CB 3.35Å; A248-I252 VanDerWaalsContact O-CG1 3.26Å; A248-I252 WeakPolarHBondContact O-CG1 3.44Å; A248-I252 PolarHBondContact O-N 2.87Å
249	A	92.3	Very high	91.2	Very high	4 Å²	4	42.8 Å²	42.8	3%	0.033	22%	0.224	C	C	.	.	H	α-helix	trans	-62.9	-40.7	176.7	0	0	0	0	0	112.4	M50 T54 L245 V246 I252 M253	M50-A249 HydrophobicContact CE-CB 3.68Å; T54-A249 WeakPolarHBondContact OG1-CB 3.37Å; L245-A249 VanDerWaalsContact O-CB 3.3Å; L245-A249 WeakPolarHBondContact O-CB 3.21Å; L245-A249 PolarHBondContact O-N 3.23Å; V246-A249 PolarHBondContact O-N 3.17Å; A249-I252 PolarHBondContact O-N 3.01Å; A249-M253 WeakPolarHBondContact O-CB 3.38Å; A249-M253 WeakPolarHBondContact O-CG 3.32Å; A249-M253 PolarHBondContact O-N 3.1Å
250	L	91.9	Very high	90.6	Very high	0 Å²	0	42.7 Å²	42.7	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-62.8	-44.3	173.1	-71.3	160.6	0	0	0	111.6	V142 C173 A177 M180 V246 T247 A248 I252 M253 L254	V142-L250 HydrophobicContact CG1-CD1 4.09Å; V142-L250 HydrophobicContact CG1-CD2 4.29Å; V142-L250 HydrophobicContact CG2-CD1 4.23Å; C173-L250 PolarHBondContact SG-O 3.16Å; A177-L250 HydrophobicContact CB-CB 3.82Å; A177-L250 HydrophobicContact CB-CD1 4.34Å; M180-L250 HydrophobicContact CB-CD1 4.49Å; M180-L250 HydrophobicContact CG-CD1 4.05Å; V246-L250 HydrophobicContact CG1-CD1 3.87Å; V246-L250 HydrophobicContact CG1-CG 4.5Å; V246-L250 WeakPolarHBondContact O-CG 3.48Å; V246-L250 PolarHBondContact O-N 3.16Å; T247-L250 PolarHBondContact O-N 3.41Å; A248-L250 PolarHBondContact O-N 3.16Å; L250-I252 VanDerWaalsContact C-N 3.35Å; L250-I252 PolarHBondContact O-N 2.68Å; L250-M253 HydrophobicContact CD2-CE 3.88Å; L250-M253 HydrophobicContact CG-CE 4.36Å; L250-M253 PolarHBondContact O-N 3.27Å; L250-L254 PolarHBondContact O-N 3.08Å
251	I	91.7	Very high	90	Very high	88 Å²	88	46.6 Å²	46.6	45%	0.451	24%	0.236	S	C	.	.	H	α-helix	trans	-61.8	-42.3	175.4	-67.6	164.5	0	0	0	111.1	A177 T247 A248 L254 V255	A177-I251 HydrophobicContact CB-CG1 4.38Å; T247-I251 HydrophobicContact CG2-CD1 4.16Å; T247-I251 WeakPolarHBondContact O-CG1 3.4Å; T247-I251 PolarHBondContact O-N 2.98Å; A248-I251 PolarHBondContact O-N 3.01Å; I251-L254 WeakPolarHBondContact O-CB 3.13Å; I251-L254 PolarHBondContact O-N 3.1Å; I251-V255 WeakPolarHBondContact O-CG2 3.3Å; I251-V255 PolarHBondContact O-N 3.38Å
252	I	91.3	Very high	89.2	Confident	68 Å²	68	48.1 Å²	48.1	35%	0.349	24%	0.237	S	C	.	.	H	α-helix	trans	-63.5	-43.1	175.3	-69.1	164.3	0	0	0	110.5	M50 A248 A249 L250 L254 V255 F256	M50-I252 HydrophobicContact CE-CB 4.11Å; M50-I252 HydrophobicContact CE-CD1 4.01Å; M50-I252 HydrophobicContact CE-CG2 3.94Å; M50-I252 HydrophobicContact CG-CG2 3.97Å; M50-I252 HydrophobicContact SD-CG2 4.12Å; A248-I252 WeakPolarHBondContact O-CB 3.35Å; A248-I252 VanDerWaalsContact O-CG1 3.26Å; A248-I252 WeakPolarHBondContact O-CG1 3.44Å; A248-I252 PolarHBondContact O-N 2.87Å; A249-I252 PolarHBondContact O-N 3.01Å; L250-I252 VanDerWaalsContact C-N 3.35Å; L250-I252 PolarHBondContact O-N 2.68Å; I252-L254 VanDerWaalsContact C-N 3.32Å; I252-L254 PolarHBondContact O-N 3.44Å; I252-V255 PolarHBondContact O-N 3.06Å; I252-F256 HydrophobicContact CG2-CD2 3.69Å; I252-F256 HydrophobicContact CG2-CE2 3.84Å; I252-F256 WeakPolarHBondContact O-CD2 3.43Å; I252-F256 PolarHBondContact O-N 3.24Å
253	M	88.4	Confident	88	Confident	6 Å²	6	47.6 Å²	47.6	3%	0.03	24%	0.235	C	C	.	.	H	α-helix	trans	-62.4	-36.4	174.3	-74.8	-168.3	-70.7	0	0	112.5	L47 M50 A51 T54 A249 L250 A257	L47-M253 HydrophobicContact CD2-CB 3.88Å; L47-M253 HydrophobicContact CD2-CG 3.94Å; L47-M253 WeakPolarHBondContact CD2-O 3.45Å; M50-M253 HydrophobicContact CB-CG 3.48Å; M50-M253 VanDerWaalsContact CB-CG 3.48Å; M50-M253 HydrophobicContact CB-SD 3.97Å; M50-M253 HydrophobicContact CG-CG 4.38Å; A51-M253 HydrophobicContact CB-SD 4.17Å; T54-M253 HydrophobicContact CG2-CE 4.38Å; T54-M253 WeakPolarHBondContact OG1-CE 3.28Å; A249-M253 WeakPolarHBondContact O-CB 3.38Å; A249-M253 WeakPolarHBondContact O-CG 3.32Å; A249-M253 PolarHBondContact O-N 3.1Å; L250-M253 HydrophobicContact CD2-CE 3.88Å; L250-M253 HydrophobicContact CG-CE 4.36Å; L250-M253 PolarHBondContact O-N 3.27Å; M253-A257 WeakPolarHBondContact O-CB 3.3Å; M253-A257 PolarHBondContact O-N 2.91Å
254	L	90	Very high	87	Confident	41 Å²	41	47.9 Å²	47.9	22%	0.215	24%	0.236	C	C	.	.	H	α-helix	trans	-61.5	-48.1	172.1	-177.2	161.3	0	0	0	111.1	L170 P174 L250 I251 I252 F256 A257 L258	L170-L254 HydrophobicContact CD2-CG 4.25Å; P174-L254 HydrophobicContact CB-CD1 3.59Å; P174-L254 HydrophobicContact CG-CD1 3.92Å; L250-L254 PolarHBondContact O-N 3.08Å; I251-L254 WeakPolarHBondContact O-CB 3.13Å; I251-L254 PolarHBondContact O-N 3.1Å; I252-L254 VanDerWaalsContact C-N 3.32Å; I252-L254 PolarHBondContact O-N 3.44Å; L254-F256 PolarHBondContact O-N 3.01Å; L254-A257 PolarHBondContact O-N 3.49Å; L254-L258 HydrophobicContact CD2-CD1 3.71Å; L254-L258 HydrophobicContact CD2-CG 4.13Å; L254-L258 WeakPolarHBondContact O-CG 3.5Å; L254-L258 PolarHBondContact O-N 2.89Å
255	V	89.8	Confident	85.7	Confident	64 Å²	64	48.4 Å²	48.4	39%	0.388	24%	0.243	S	C	.	.	H	α-helix	trans	-63.5	-41.8	179.3	173.2	0	0	0	0	111.9	I251 I252 L258 K259	I251-V255 WeakPolarHBondContact O-CG2 3.3Å; I251-V255 PolarHBondContact O-N 3.38Å; I252-V255 PolarHBondContact O-N 3.06Å; V255-L258 WeakPolarHBondContact O-CB 3.47Å; V255-L258 PolarHBondContact O-N 3.22Å; V255-K259 PolarHBondContact O-N 3.46Å
256	F	86.7	Confident	84.4	Confident	51 Å²	51	50 Å²	50	22%	0.224	25%	0.253	C	S	.	.	H	α-helix	trans	-72.5	-31.1	175.6	-80.4	-75.3	0	0	0	112.9	P43 I46 L47 I252 L254 K259 T260	P43-F256 HydrophobicContact CB-CD1 4.46Å; I46-F256 HydrophobicContact CB-CD1 4.37Å; I46-F256 HydrophobicContact CB-CE1 4.45Å; I46-F256 HydrophobicContact CB-CG 4.49Å; I46-F256 HydrophobicContact CD1-CD1 4.2Å; I46-F256 HydrophobicContact CD1-CE1 3.55Å; I46-F256 HydrophobicContact CD1-CZ 3.82Å; I46-F256 HydrophobicContact CG2-CD1 4.22Å; I46-F256 HydrophobicContact CG2-CD2 3.73Å; I46-F256 HydrophobicContact CG2-CE1 4.21Å; I46-F256 HydrophobicContact CG2-CE2 3.73Å; I46-F256 HydrophobicContact CG2-CG 3.99Å; I46-F256 HydrophobicContact CG2-CZ 3.98Å; L47-F256 HydrophobicContact CD2-CB 3.78Å; L47-F256 HydrophobicContact CG-CB 4.02Å; I252-F256 HydrophobicContact CG2-CD2 3.69Å; I252-F256 HydrophobicContact CG2-CE2 3.84Å; I252-F256 WeakPolarHBondContact O-CD2 3.43Å; I252-F256 PolarHBondContact O-N 3.24Å; L254-F256 PolarHBondContact O-N 3.01Å; F256-K259 PolarHBondContact O-N 2.83Å; F256-T260 WeakPolarHBondContact O-CB 3.37Å; F256-T260 PolarHBondContact O-N 3.27Å; F256-T260 PolarHBondContact O-OG1 3.49Å
257	A	85.7	Confident	82.7	Confident	0 Å²	0	54.4 Å²	54.4	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-67.1	-36.4	170.2	0	0	0	0	0	112	L47 V169 L170 M253 L254 R261	L47-A257 HydrophobicContact CD1-CB 4.47Å; V169-A257 HydrophobicContact CG1-CB 4.1Å; L170-A257 HydrophobicContact CD2-CB 3.77Å; L170-A257 HydrophobicContact CG-CB 3.96Å; M253-A257 WeakPolarHBondContact O-CB 3.3Å; M253-A257 PolarHBondContact O-N 2.91Å; L254-A257 PolarHBondContact O-N 3.49Å; A257-R261 VanDerWaalsContact O-CB 3.25Å; A257-R261 WeakPolarHBondContact O-CB 3.39Å; A257-R261 PolarHBondContact O-N 2.83Å
258	L	85	Confident	80.9	Confident	76 Å²	76	55 Å²	55	40%	0.398	28%	0.278	S	S	.	.	H	α-helix	trans	-62	-54	171.6	-76.5	177.4	0	0	0	110.5	L170 L254 V255 T260 R261 Q262	L170-L258 HydrophobicContact CD1-CD2 3.92Å; L170-L258 HydrophobicContact CD2-CB 4.38Å; L170-L258 HydrophobicContact CD2-CD2 3.6Å; L170-L258 HydrophobicContact CD2-CG 3.59Å; L170-L258 HydrophobicContact CG-CD2 4.4Å; L254-L258 HydrophobicContact CD2-CD1 3.71Å; L254-L258 HydrophobicContact CD2-CG 4.13Å; L254-L258 WeakPolarHBondContact O-CG 3.5Å; L254-L258 PolarHBondContact O-N 2.89Å; V255-L258 WeakPolarHBondContact O-CB 3.47Å; V255-L258 PolarHBondContact O-N 3.22Å; L258-T260 VanDerWaalsContact C-N 3.34Å; L258-T260 PolarHBondContact O-N 2.65Å; L258-R261 PolarHBondContact O-N 3.33Å; L258-Q262 WeakPolarHBondContact O-CB 3.3Å; L258-Q262 WeakPolarHBondContact O-CG 3.45Å; L258-Q262 PolarHBondContact O-N 3.2Å
259	K	84.2	Confident	78.9	Confident	116 Å²	116	61 Å²	61	50%	0.504	30%	0.296	S	S	.	.	H	α-helix	trans	-59.9	-41.5	178.6	-75.4	-171	173.5	-173.9	0	112.6	V255 F256 Q262 K263	V255-K259 PolarHBondContact O-N 3.46Å; F256-K259 PolarHBondContact O-N 2.83Å; K259-Q262 PolarHBondContact O-N 3.42Å; K259-K263 PolarHBondContact O-N 3.21Å
260	T	78.9	Confident	76.7	Confident	0 Å²	0	67.9 Å²	67.9	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-62.4	-46.5	176.3	-56.4	0	0	0	0	110.5	F37 P43 Y166 F256 L258 K263 I264	F37-T260 HydrophobicContact CE2-CG2 4.02Å; F37-T260 HydrophobicContact CZ-CG2 3.88Å; P43-T260 WeakPolarHBondContact CB-OG1 3.17Å; Y166-T260 HydrophobicContact CD1-CG2 4Å; Y166-T260 HydrophobicContact CE1-CG2 3.54Å; Y166-T260 HydrophobicContact CE2-CG2 4.14Å; Y166-T260 HydrophobicContact CG-CG2 4.49Å; F256-T260 WeakPolarHBondContact O-CB 3.37Å; F256-T260 PolarHBondContact O-N 3.27Å; F256-T260 PolarHBondContact O-OG1 3.49Å; L258-T260 VanDerWaalsContact C-N 3.34Å; L258-T260 PolarHBondContact O-N 2.65Å; T260-K263 PolarHBondContact O-N 2.98Å; T260-I264 HydrophobicContact CG2-CD1 3.72Å; T260-I264 WeakPolarHBondContact O-CB 3.33Å; T260-I264 WeakPolarHBondContact O-CD1 3.06Å; T260-I264 WeakPolarHBondContact O-CG1 3.42Å; T260-I264 PolarHBondContact O-N 3.21Å
261	R	80.8	Confident	74.8	Confident	99 Å²	99	71 Å²	71	37%	0.374	34%	0.344	S	S	.	.	H	α-helix	trans	-65.9	-37.6	176.6	-176.6	175.6	173.5	-176.6	-2.1	113	L170 A257 L258 I264 N265	L170-R261 HydrophobicContact CD1-CB 4.22Å; A257-R261 VanDerWaalsContact O-CB 3.25Å; A257-R261 WeakPolarHBondContact O-CB 3.39Å; A257-R261 PolarHBondContact O-N 2.83Å; L258-R261 PolarHBondContact O-N 3.33Å; R261-I264 PolarHBondContact O-N 2.92Å; R261-N265 WeakPolarHBondContact O-CB 3.28Å; R261-N265 PolarHBondContact O-N 3.27Å
262	Q	76.3	Confident	73.3	Confident	115 Å²	115	67.3 Å²	67.3	54%	0.537	33%	0.326	S	S	.	.	H	α-helix	trans	-64	-49.8	175	-76.9	171.8	-32	0	0	110.8	L258 K259 I264 N265 N266	L258-Q262 WeakPolarHBondContact O-CB 3.3Å; L258-Q262 WeakPolarHBondContact O-CG 3.45Å; L258-Q262 PolarHBondContact O-N 3.2Å; K259-Q262 PolarHBondContact O-N 3.42Å; Q262-I264 VanDerWaalsContact C-N 3.34Å; Q262-I264 PolarHBondContact O-N 2.95Å; Q262-N265 WeakPolarHBondContact O-CB 3.15Å; Q262-N265 PolarHBondContact O-N 3.24Å; Q262-N266 PolarHBondContact O-N 3.44Å; Q262-N266 PolarHBondContact O-OD1 3.3Å
263	K	70.3	Confident	71.7	Confident	46 Å²	46	66.8 Å²	66.8	20%	0.2	32%	0.323	C	S	.	.	H	α-helix	trans	-61.7	-39.9	174.9	-73.8	-144.2	168.4	-159.4	0	112.2	E33 Q35 K259 T260 N265 N266 Y267	E33-K263 IonicContact OE1-NZ 3.68Å; E33-K263 IonicContact OE2-NZ 2.81Å; E33-K263 PolarHBondContact OE2-NZ 2.75Å; Q35-K263 HydrophobicContact CG-CD 4.16Å; Q35-K263 VanDerWaalsContact OE1-CE 3.25Å; K259-K263 PolarHBondContact O-N 3.21Å; T260-K263 PolarHBondContact O-N 2.98Å; K263-N265 PolarHBondContact O-N 3.36Å; K263-N266 PolarHBondContact O-N 2.87Å; K263-Y267 HydrophobicContact CB-CD2 3.95Å; K263-Y267 HydrophobicContact CB-CE2 4.27Å; K263-Y267 HydrophobicContact CD-CD2 4.12Å; K263-Y267 HydrophobicContact CD-CE2 3.75Å; K263-Y267 HydrophobicContact CG-CD2 4.04Å; K263-Y267 HydrophobicContact CG-CE2 3.82Å; K263-Y267 WeakPolarHBondContact O-CD2 3.45Å; K263-Y267 PolarHBondContact O-N 2.81Å
264	I	70.6	Confident	70.5	Confident	6 Å²	6	68 Å²	68	3%	0.031	33%	0.327	C	S	.	.	H	α-helix	trans	-64.8	-20.5	172.6	-67.5	165.1	0	0	0	113.2	F37 R163 Y166 T260 R261 Q262 I272 W274	F37-I264 HydrophobicContact CE2-CD1 4Å; F37-I264 HydrophobicContact CE2-CG1 3.81Å; F37-I264 HydrophobicContact CZ-CG1 4.27Å; R163-I264 HydrophobicContact CG-CG2 3.55Å; R163-I264 VanDerWaalsContact CZ-O 3.28Å; R163-I264 PolarHBondContact NE-O 2.88Å; R163-I264 VanDerWaalsContact NE-O 3.16Å; R163-I264 PolarHBondContact NH2-O 3.46Å; Y166-I264 HydrophobicContact CD2-CD1 3.79Å; Y166-I264 HydrophobicContact CE2-CD1 3.64Å; T260-I264 HydrophobicContact CG2-CD1 3.72Å; T260-I264 WeakPolarHBondContact O-CB 3.33Å; T260-I264 WeakPolarHBondContact O-CD1 3.06Å; T260-I264 WeakPolarHBondContact O-CG1 3.42Å; T260-I264 PolarHBondContact O-N 3.21Å; R261-I264 PolarHBondContact O-N 2.92Å; Q262-I264 VanDerWaalsContact C-N 3.34Å; Q262-I264 PolarHBondContact O-N 2.95Å; I264-I272 HydrophobicContact CB-CD1 4.28Å; I264-I272 HydrophobicContact CG1-CD1 3.88Å; I264-W274 HydrophobicContact CD1-CH2 3.76Å; I264-W274 HydrophobicContact CD1-CZ2 3.68Å; I264-W274 HydrophobicContact CG1-CZ2 4.11Å
265	N	69.3	Low	68.6	Low	101 Å²	101	72.9 Å²	72.9	54%	0.54	35%	0.347	S	S	.	.	H	α-helix	trans	-87.3	-39.5	176.6	-164.9	77.7	0	0	0	112.1	R261 Q262 K263	R261-N265 WeakPolarHBondContact O-CB 3.28Å; R261-N265 PolarHBondContact O-N 3.27Å; Q262-N265 WeakPolarHBondContact O-CB 3.15Å; Q262-N265 PolarHBondContact O-N 3.24Å; K263-N265 PolarHBondContact O-N 3.36Å
266	N	67.4	Low	66.1	Low	122 Å²	122	76.9 Å²	76.9	65%	0.652	36%	0.359	S	S	*	.	H	α-helix	trans	-82.5	-48.7	-174.8	-63.4	19.4	0	0	0	112.3	Q262 K263 G268	Q262-N266 PolarHBondContact O-N 3.44Å; Q262-N266 PolarHBondContact O-OD1 3.3Å; K263-N266 PolarHBondContact O-N 2.87Å; N266-G268 PolarHBondContact O-N 2.94Å; N266-G268 VanDerWaalsContact O-N 3.17Å
267	Y	59.5	Low	63.8	Low	91 Å²	91	78.7 Å²	78.7	36%	0.357	37%	0.374	S	S	.	.	S	Bend	trans	-88.7	29.5	-172.7	-61.9	-88.8	0	0	0	113.6	K263 N271	K263-Y267 HydrophobicContact CB-CD2 3.95Å; K263-Y267 HydrophobicContact CB-CE2 4.27Å; K263-Y267 HydrophobicContact CD-CD2 4.12Å; K263-Y267 HydrophobicContact CD-CE2 3.75Å; K263-Y267 HydrophobicContact CG-CD2 4.04Å; K263-Y267 HydrophobicContact CG-CE2 3.82Å; K263-Y267 WeakPolarHBondContact O-CD2 3.45Å; K263-Y267 PolarHBondContact O-N 2.81Å; Y267-N271 WeakPolarHBondContact O-CB 3.3Å
268	G	54.7	Low	61.3	Low	21 Å²	21	87.4 Å²	87.4	22%	0.216	41%	0.412	C	S	.	.	T	Hydrogen-bonded Turn	trans	61.3	-153.5	-179.2	0	0	0	0	0	114.9	N266 E270	N266-G268 PolarHBondContact O-N 2.94Å; N266-G268 VanDerWaalsContact O-N 3.17Å; G268-E270 WeakPolarHBondContact CA-OE1 3.34Å
269	K	52.4	Low	58.8	Low	167 Å²	167	87.6 Å²	87.6	73%	0.726	42%	0.416	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.3	-24.6	161	-89.2	-171	172.7	-173.8	0	111.9
270	E	46	Very low	56.4	Low	148 Å²	148	86.3 Å²	86.3	69%	0.692	42%	0.418	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.4	-37.2	-170.8	30.1	-78.9	98.2	0	0	113.2	G268 I272	G268-E270 WeakPolarHBondContact CA-OE1 3.34Å; E270-I272 VanDerWaalsContact C-N 3.26Å; E270-I272 PolarHBondContact O-N 3Å
271	N	52.6	Low	54.1	Low	65 Å²	65	93.3 Å²	93.3	35%	0.348	46%	0.455	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88.2	17.2	-171.6	-54.3	12.3	0	0	0	113.4	Q35 Y267	Q35-N271 PolarHBondContact N-O 2.96Å; Y267-N271 WeakPolarHBondContact O-CB 3.3Å
272	I	59.2	Low	51.8	Low	11 Å²	11	92.7 Å²	92.7	6%	0.056	46%	0.459	C	S	.	.	B	Isolated β-bridge	trans	-121.6	102.3	-168.2	-52.6	-175.8	0	0	0	111.9	F37 I264 E270 W274	F37-I272 HydrophobicContact CD2-CG2 3.24Å; F37-I272 HydrophobicContact CE2-CG2 3.47Å; F37-I272 VanDerWaalsContact CE2-CG2 3.47Å; F37-I272 HydrophobicContact CG-CG2 3.92Å; F37-I272 HydrophobicContact CZ-CG2 4.31Å; I264-I272 HydrophobicContact CB-CD1 4.28Å; I264-I272 HydrophobicContact CG1-CD1 3.88Å; E270-I272 VanDerWaalsContact C-N 3.26Å; E270-I272 PolarHBondContact O-N 3Å; I272-W274 HydrophobicContact CG2-CD2 4.34Å; I272-W274 HydrophobicContact CG2-CG 4.44Å; I272-W274 HydrophobicContact CG2-CZ2 4.13Å; I272-W274 PolarHBondContact O-N 3.39Å; I272-W274 VanDerWaalsContact O-N 3.12Å
273	L	57.7	Low	50	Low	57 Å²	57	93.6 Å²	93.6	30%	0.298	47%	0.467	S	S	.	.			trans	-84	87.2	-177	-63.2	175.4	0	0	0	111.8	F34 Q35 F37 Y38 V277	F34-L273 HydrophobicContact CB-CD1 4.14Å; Q35-L273 PolarHBondContact O-N 3.37Å; F37-L273 PolarHBondContact N-O 2.9Å; Y38-L273 PolarHBondContact N-O 3.21Å; L273-V277 HydrophobicContact CD2-CG2 4.41Å
274	W	62.9	Low	48.2	Very low	32 Å²	32	94.6 Å²	94.6	12%	0.121	48%	0.484	C	S	.	.			trans	-71.6	-30.6	-178.3	-73.9	99.6	0	0	0	115.7	F37 S160 Q161 Y166 I264 I272	F37-W274 HydrophobicContact CB-CE3 4.33Å; F37-W274 HydrophobicContact CD2-CD2 4.01Å; F37-W274 AromaticContact CD2-CE2 3.87Å; F37-W274 AromaticContact CD2-CE3 3.91Å; F37-W274 HydrophobicContact CD2-CE3 3.91Å; F37-W274 AromaticContact CD2-CH2 3.52Å; F37-W274 HydrophobicContact CD2-CH2 3.52Å; F37-W274 AromaticContact CD2-CZ2 3.64Å; F37-W274 HydrophobicContact CD2-CZ2 3.64Å; F37-W274 AromaticContact CD2-CZ3 3.67Å; F37-W274 HydrophobicContact CD2-CZ3 3.67Å; F37-W274 AromaticContact CE2-CH2 3.68Å; F37-W274 HydrophobicContact CE2-CH2 3.68Å; F37-W274 AromaticContact CE2-CZ2 3.74Å; F37-W274 HydrophobicContact CE2-CZ2 3.74Å; F37-W274 HydrophobicContact CE2-CZ3 4.27Å; S160-W274 WeakPolarHBondContact O-CH2 3.48Å; S160-W274 WeakPolarHBondContact O-CZ3 3.37Å; Q161-W274 HydrophobicContact CB-CD2 4.38Å; Q161-W274 HydrophobicContact CB-CZ2 4.42Å; Q161-W274 HydrophobicContact CG-CB 4.42Å; Q161-W274 HydrophobicContact CG-CD2 3.77Å; Q161-W274 HydrophobicContact CG-CE3 4.25Å; Q161-W274 HydrophobicContact CG-CG 3.84Å; Y166-W274 AromaticContact CE2-CH2 3.81Å; Y166-W274 HydrophobicContact CE2-CH2 3.81Å; Y166-W274 WeakPolarHBondContact OH-CH2 3.5Å; Y166-W274 WeakPolarHBondContact OH-CZ3 3.28Å; I264-W274 HydrophobicContact CD1-CH2 3.76Å; I264-W274 HydrophobicContact CD1-CZ2 3.68Å; I264-W274 HydrophobicContact CG1-CZ2 4.11Å; I272-W274 HydrophobicContact CG2-CD2 4.34Å; I272-W274 HydrophobicContact CG2-CG 4.44Å; I272-W274 HydrophobicContact CG2-CZ2 4.13Å; I272-W274 PolarHBondContact O-N 3.39Å; I272-W274 VanDerWaalsContact O-N 3.12Å
275	K	51.4	Low	46.5	Very low	143 Å²	143	99.8 Å²	99.8	62%	0.622	52%	0.518	S	S	*	.	S	Bend	trans	-102	154.2	170.5	-68.2	-178.3	177.3	-179.7	0	107.5	V277	K275-V277 VanDerWaalsContact C-N 3.26Å; K275-V277 PolarHBondContact O-N 3.05Å
276	K	37.4	Very low	45.2	Very low	147 Å²	147	98 Å²	98	64%	0.639	51%	0.512	S	S	*	.			trans	-61.8	104.6	147.9	-122.7	-173.1	-169.5	-168.7	0	104.5	Y38 K278	Y38-K276 HydrophobicContact CD1-CB 3.72Å; Y38-K276 HydrophobicContact CD1-CD 3.8Å; Y38-K276 HydrophobicContact CD1-CG 3.45Å; Y38-K276 VanDerWaalsContact CD1-CG 3.45Å; Y38-K276 HydrophobicContact CD2-CB 3.86Å; Y38-K276 HydrophobicContact CE1-CB 3.87Å; Y38-K276 HydrophobicContact CE1-CD 3.51Å; Y38-K276 HydrophobicContact CE1-CG 3.69Å; Y38-K276 HydrophobicContact CE2-CB 3.99Å; Y38-K276 HydrophobicContact CG-CB 3.7Å; Y38-K276 HydrophobicContact CG-CG 3.9Å; Y38-K276 VanDerWaalsContact CG-N 3.34Å; K276-K278 PolarHBondContact O-N 3.39Å
277	V	38.4	Very low	44.1	Very low	90 Å²	90	99.9 Å²	99.9	55%	0.545	52%	0.517	S	S	.	.			trans	-52.9	122.6	142.6	-178.1	0	0	0	0	103.4	L273 K275 V279	L273-V277 HydrophobicContact CD2-CG2 4.41Å; K275-V277 VanDerWaalsContact C-N 3.26Å; K275-V277 PolarHBondContact O-N 3.05Å; V277-V279 HydrophobicContact CG1-CG2 4.36Å; V277-V279 PolarHBondContact O-N 3Å
278	K	31.5	Very low	43.6	Very low	183 Å²	183	101.2 Å²	101.2	80%	0.796	53%	0.53	S	S	*	.			trans	-66.4	90.9	156.2	-82.5	-172.2	177.4	-177	0	104.1	K276 V280	K276-K278 PolarHBondContact O-N 3.39Å; K278-V280 PolarHBondContact O-N 3.29Å
279	V	34.1	Very low	43.3	Very low	79 Å²	79	101 Å²	101	48%	0.479	53%	0.525	S	S	.	.			trans	-57.9	92.8	142	-179.1	0	0	0	0	102.9	V277 L283	V277-V279 HydrophobicContact CG1-CG2 4.36Å; V277-V279 PolarHBondContact O-N 3Å; V279-L283 HydrophobicContact CG1-CB 4.46Å
280	V	32.6	Very low	43.3	Very low	89 Å²	89	97.9 Å²	97.9	54%	0.539	51%	0.512	S	S	.	.			trans	-54.6	136.9	134.2	-169	0	0	0	0	104.1	K278 D282	K278-V280 PolarHBondContact O-N 3.29Å; V280-D282 WeakPolarHBondContact CB-OD2 3.43Å; V280-D282 WeakPolarHBondContact CG1-OD1 3.48Å; V280-D282 WeakPolarHBondContact CG1-OD2 3.33Å; V280-D282 PolarHBondContact O-N 2.82Å
281	D	31	Very low	43.5	Very low	147 Å²	147	92.7 Å²	92.7	79%	0.786	50%	0.495	S	S	*	.	S	Bend	trans	-73.8	47.7	-173.1	-67.8	-60.6	0	0	0	112.5	L283	D281-L283 VanDerWaalsContact C-N 3.3Å
282	D	32.4	Very low	43.5	Very low	86 Å²	86	91.9 Å²	91.9	46%	0.46	49%	0.487	S	S	.	.			trans	-94.7	19.3	174.4	-50.7	-28.9	0	0	0	111.5	V280 A284	V280-D282 WeakPolarHBondContact CB-OD2 3.43Å; V280-D282 WeakPolarHBondContact CG1-OD1 3.48Å; V280-D282 WeakPolarHBondContact CG1-OD2 3.33Å; V280-D282 PolarHBondContact O-N 2.82Å; D282-A284 CarbonylContact C-O 3.56Å
283	L	38.4	Very low	43.2	Very low	135 Å²	135	92.8 Å²	92.8	71%	0.707	49%	0.493	S	S	*	.			trans	-135.5	13.3	-173	-103.3	164.9	0	0	0	114.6	V279 D281	V279-L283 HydrophobicContact CG1-CB 4.46Å; D281-L283 VanDerWaalsContact C-N 3.3Å
284	A	32.9	Very low	42.9	Very low	66 Å²	66	95.3 Å²	95.3	55%	0.545	51%	0.507	S	S	.	.	S	Bend		-62.7	141.9	123.7	0	0	0	0	0	107.3	D282 P286	D282-A284 CarbonylContact C-O 3.56Å; A284-P286 WeakPolarHBondContact O-CD 3.5Å; A284-P286 VanDerWaalsContact O-N 3.17Å
285	P	34.3	Very low	42.4	Very low	115 Å²	115	100.1 Å²	100.1	75%	0.747	54%	0.535	S	S	*	.			trans	-56.7	123.6	160.1	27.4	-31.9	0	0	0	106.3	E287	P285-E287 PolarHBondContact O-N 3.19Å
286	P	41.4	Very low	42.2	Very low	64 Å²	64	95.8 Å²	95.8	42%	0.416	52%	0.52	S	S	.	.			trans	-71.3	101.2	-172.2	27	-33.9	0	0	0	109.3	A284 D288 V289	A284-P286 WeakPolarHBondContact O-CD 3.5Å; A284-P286 VanDerWaalsContact O-N 3.17Å; P286-D288 HydrophobicContact CB-CB 4.25Å; P286-D288 PolarHBondContact O-N 3.48Å; P286-V289 HydrophobicContact CB-CB 4.4Å; P286-V289 HydrophobicContact CB-CG2 3.94Å; P286-V289 HydrophobicContact CG-CB 4.07Å; P286-V289 HydrophobicContact CG-CG2 3.6Å; P286-V289 PolarHBondContact O-N 2.7Å
287	E	45.6	Very low	42.5	Very low	161 Å²	161	92 Å²	92	75%	0.752	51%	0.513	S	S	*	.	H	α-helix	trans	-48	-37.7	157.3	-69.3	-175.6	117.3	0	0	108.5	P285 V289 E290 A291	P285-E287 PolarHBondContact O-N 3.19Å; E287-V289 PolarHBondContact O-N 3.39Å; E287-E290 PolarHBondContact O-N 3.31Å; E287-E290 VanDerWaalsContact O-N 3.07Å; E287-A291 WeakPolarHBondContact O-CA 3.2Å; E287-A291 WeakPolarHBondContact O-CB 3.36Å; E287-A291 PolarHBondContact O-N 3.5Å
288	D	49.7	Very low	42.4	Very low	119 Å²	119	91.1 Å²	91.1	64%	0.636	51%	0.514	S	S	*	.	H	α-helix	trans	-55.3	-4.7	169.1	-80	-4.5	0	0	0	117.4	P286 W292 K501	P286-D288 HydrophobicContact CB-CB 4.25Å; P286-D288 PolarHBondContact O-N 3.48Å; D288-W292 VanDerWaalsContact O-CB 3.28Å; D288-W292 WeakPolarHBondContact O-CB 3.14Å; D288-K501 PolarHBondContact O-NZ 2.94Å
289	V	47.8	Very low	42.6	Very low	18 Å²	18	87.6 Å²	87.6	11%	0.109	51%	0.51	C	S	.	.	H	α-helix	trans	-102.2	-46.5	166.5	174.8	0	0	0	0	110.5	P286 E287 W292 V293 F426 H430 K501	P286-V289 HydrophobicContact CB-CB 4.4Å; P286-V289 HydrophobicContact CB-CG2 3.94Å; P286-V289 HydrophobicContact CG-CB 4.07Å; P286-V289 HydrophobicContact CG-CG2 3.6Å; P286-V289 PolarHBondContact O-N 2.7Å; E287-V289 PolarHBondContact O-N 3.39Å; V289-W292 PolarHBondContact O-N 3.34Å; V289-V293 WeakPolarHBondContact O-CB 3.29Å; V289-V293 VanDerWaalsContact O-CG2 3.3Å; V289-V293 WeakPolarHBondContact O-CG2 3.26Å; V289-V293 PolarHBondContact O-N 3.34Å; V289-F426 HydrophobicContact CG1-CE1 4Å; V289-F426 HydrophobicContact CG1-CZ 3.82Å; V289-H430 VanDerWaalsContact CG1-CE1 3.42Å; V289-H430 WeakPolarHBondContact CG1-CE1 3.49Å; V289-K501 HydrophobicContact CG2-CD 4.31Å
290	E	51.5	Low	42.8	Very low	100 Å²	100	90 Å²	90	47%	0.467	53%	0.527	S	S	.	.	H	α-helix	trans	-66.8	-44.8	176.1	-63.2	-165.8	140.5	0	0	111.9	E287 W292 V293 N294 K434	E287-E290 PolarHBondContact O-N 3.31Å; E287-E290 VanDerWaalsContact O-N 3.07Å; E290-W292 VanDerWaalsContact C-N 3.33Å; E290-W292 PolarHBondContact O-N 2.83Å; E290-V293 PolarHBondContact O-N 2.88Å; E290-N294 VanDerWaalsContact O-CB 3.3Å; E290-N294 WeakPolarHBondContact O-CB 3.31Å; E290-N294 PolarHBondContact O-N 2.92Å; E290-N294 PolarHBondContact O-ND2 3.11Å; E290-K434 IonicContact OE1-NZ 3.18Å; E290-K434 PolarHBondContact OE1-NZ 2.87Å
291	A	50.7	Low	42.8	Very low	39 Å²	39	94.6 Å²	94.6	32%	0.322	54%	0.543	S	S	.	.	H	α-helix	trans	-64.9	-31.8	173.6	0	0	0	0	0	112.8	E287 N295	E287-A291 WeakPolarHBondContact O-CA 3.2Å; E287-A291 WeakPolarHBondContact O-CB 3.36Å; E287-A291 PolarHBondContact O-N 3.5Å; A291-N295 WeakPolarHBondContact O-CB 3.34Å; A291-N295 PolarHBondContact O-N 3.41Å; A291-N295 PolarHBondContact O-ND2 3.35Å
292	W	51.9	Low	43.1	Very low	48 Å²	48	96 Å²	96	18%	0.182	55%	0.545	C	S	.	.	H	α-helix	trans	-71.1	-46.1	172.4	-178.6	85.1	0	0	0	111.4	D288 V289 E290 N294 N295 V296 K423 F426 V504	D288-W292 VanDerWaalsContact O-CB 3.28Å; D288-W292 WeakPolarHBondContact O-CB 3.14Å; V289-W292 PolarHBondContact O-N 3.34Å; E290-W292 VanDerWaalsContact C-N 3.33Å; E290-W292 PolarHBondContact O-N 2.83Å; W292-N294 VanDerWaalsContact C-N 3.3Å; W292-N294 PolarHBondContact O-N 2.79Å; W292-N295 PolarHBondContact O-N 3.02Å; W292-V296 HydrophobicContact CD2-CG2 4.44Å; W292-V296 HydrophobicContact CZ2-CG2 4.48Å; W292-V296 WeakPolarHBondContact O-CB 3.48Å; W292-V296 WeakPolarHBondContact O-CG2 3.25Å; W292-V296 PolarHBondContact O-N 2.95Å; W292-K423 HydrophobicContact CH2-CB 4.24Å; W292-K423 HydrophobicContact CH2-CD 3.79Å; W292-K423 HydrophobicContact CH2-CG 3.81Å; W292-K423 HydrophobicContact CZ2-CD 4.45Å; W292-K423 HydrophobicContact CZ3-CD 4.25Å; W292-K423 HydrophobicContact CZ3-CG 4.21Å; W292-F426 HydrophobicContact CE3-CE1 4.34Å; W292-F426 AromaticContact CZ3-CD1 3.9Å; W292-F426 HydrophobicContact CZ3-CD1 3.9Å; W292-F426 HydrophobicContact CZ3-CE1 4.1Å; W292-V504 HydrophobicContact CH2-CG1 4.47Å; W292-V504 HydrophobicContact CZ2-CG1 3.87Å
293	V	52.8	Low	43	Very low	31 Å²	31	96.8 Å²	96.8	19%	0.188	56%	0.564	C	S	.	*	H	α-helix	trans	-58.9	-42.8	173.9	171.1	0	0	0	0	110.5	V289 E290 V296 S297 F426	V289-V293 WeakPolarHBondContact O-CB 3.29Å; V289-V293 VanDerWaalsContact O-CG2 3.3Å; V289-V293 WeakPolarHBondContact O-CG2 3.26Å; V289-V293 PolarHBondContact O-N 3.34Å; E290-V293 PolarHBondContact O-N 2.88Å; V293-V296 CarbonylContact O-C 3.33Å; V293-S297 WeakPolarHBondContact O-CB 3.41Å; V293-S297 PolarHBondContact O-N 3.23Å; V293-S297 VanDerWaalsContact O-N 3.14Å; V293-S297 PolarHBondContact O-OG 3.44Å; V293-F426 HydrophobicContact CG2-CE1 4.25Å
294	N	51.8	Low	42.7	Very low	109 Å²	109	97.9 Å²	97.9	58%	0.583	57%	0.569	S	S	*	*	H	α-helix	trans	-64.7	-51.6	176.8	-69.9	-21.4	0	0	0	112.1	E290 W292 V296 S297 A298	E290-N294 VanDerWaalsContact O-CB 3.3Å; E290-N294 WeakPolarHBondContact O-CB 3.31Å; E290-N294 PolarHBondContact O-N 2.92Å; E290-N294 PolarHBondContact O-ND2 3.11Å; W292-N294 VanDerWaalsContact C-N 3.3Å; W292-N294 PolarHBondContact O-N 2.79Å; N294-V296 VanDerWaalsContact C-N 3.27Å; N294-V296 PolarHBondContact O-N 3.33Å; N294-S297 PolarHBondContact O-N 2.83Å; N294-S297 VanDerWaalsContact O-N 3.08Å; N294-A298 PolarHBondContact O-N 3.48Å
295	N	51.8	Low	42.7	Very low	133 Å²	133	99.9 Å²	99.9	71%	0.711	59%	0.586	S	S	*	*	H	α-helix	trans	-61.5	-33.8	-179.8	-77.9	-18.9	0	0	0	112.8	A291 W292 S297	A291-N295 WeakPolarHBondContact O-CB 3.34Å; A291-N295 PolarHBondContact O-N 3.41Å; A291-N295 PolarHBondContact O-ND2 3.35Å; W292-N295 PolarHBondContact O-N 3.02Å; N295-S297 VanDerWaalsContact C-N 3.34Å
296	V	47.6	Very low	42.6	Very low	52 Å²	52	99.1 Å²	99.1	32%	0.315	59%	0.589	S	S	.	*	T	Hydrogen-bonded Turn	trans	-98.1	20.3	178.9	-164.7	0	0	0	0	111.6	W292 V293 N294 K423	W292-V296 HydrophobicContact CD2-CG2 4.44Å; W292-V296 HydrophobicContact CZ2-CG2 4.48Å; W292-V296 WeakPolarHBondContact O-CB 3.48Å; W292-V296 WeakPolarHBondContact O-CG2 3.25Å; W292-V296 PolarHBondContact O-N 2.95Å; V293-V296 CarbonylContact O-C 3.33Å; N294-V296 VanDerWaalsContact C-N 3.27Å; N294-V296 PolarHBondContact O-N 3.33Å; V296-K423 HydrophobicContact CB-CD 4.34Å; V296-K423 HydrophobicContact CG1-CD 3.7Å; V296-K423 WeakPolarHBondContact O-CE 3.34Å; V296-K423 PolarHBondContact O-NZ 3.44Å
297	S	44.4	Very low	42.3	Very low	69 Å²	69	104 Å²	104	48%	0.483	61%	0.612	S	S	.	*	T	Hydrogen-bonded Turn	trans	-129	0.8	170.2	-53.2	0	0	0	0	113.5	V293 N294 N295 K423	V293-S297 WeakPolarHBondContact O-CB 3.41Å; V293-S297 PolarHBondContact O-N 3.23Å; V293-S297 VanDerWaalsContact O-N 3.14Å; V293-S297 PolarHBondContact O-OG 3.44Å; N294-S297 PolarHBondContact O-N 2.83Å; N294-S297 VanDerWaalsContact O-N 3.08Å; N295-S297 VanDerWaalsContact C-N 3.34Å; S297-K423 PolarHBondContact OG-NZ 2.86Å
298	A	35.6	Very low	41.5	Very low	70 Å²	70	106.2 Å²	106.2	58%	0.579	62%	0.615	S	S	*	*	S	Bend	trans	-69.8	126.8	168.7	0	0	0	0	0	110.1	N294	N294-A298 PolarHBondContact O-N 3.48Å
299	P	37.1	Very low	41.6	Very low	110 Å²	110	105.6 Å²	105.6	71%	0.714	62%	0.617	S	S	*	*			trans	-69.1	146.3	172.5	29.6	-33.9	0	0	0	110.2	Q301	P299-Q301 PolarHBondContact O-N 3.41Å
300	P	36.8	Very low	40.8	Very low	128 Å²	128	112 Å²	112	83%	0.831	65%	0.651	S	S	*	*			trans	-66.4	110.8	177.9	27.1	-33.6	0	0	0	109.9
301	Q	32.9	Very low	39.8	Very low	187 Å²	187	116.5 Å²	116.5	87%	0.874	67%	0.665	S	S	*	*			trans	-73.7	133.6	177.5	-172.6	164.3	-2	0	0	110.5	P299 A303	P299-Q301 PolarHBondContact O-N 3.41Å; Q301-A303 PolarHBondContact O-N 2.9Å
302	E	37.3	Very low	39.5	Very low	175 Å²	175	119.6 Å²	119.6	82%	0.818	68%	0.682	S	S	*	*			trans	-64.9	101.5	-174.5	-62.9	178	130.6	0	0	111.9	L304	E302-L304 PolarHBondContact O-N 3.3Å; E302-L304 VanDerWaalsContact O-N 3.12Å
303	A	30.7	Very low	38.4	Very low	104 Å²	104	123.4 Å²	123.4	86%	0.86	71%	0.706	S	S	*	*			trans	-75.3	95.1	168.3	0	0	0	0	0	109.4	Q301	Q301-A303 PolarHBondContact O-N 2.9Å
304	L	32.5	Very low	37.4	Very low	158 Å²	158	129 Å²	129	83%	0.827	73%	0.73	S	S	*	*			trans	-63.5	153.6	179	-69	170.1	0	0	0	112.4	E302	E302-L304 PolarHBondContact O-N 3.3Å; E302-L304 VanDerWaalsContact O-N 3.12Å
305	A	33.5	Very low	36.4	Very low	107 Å²	107	128.5 Å²	128.5	88%	0.884	73%	0.734	S	S	*	*			trans	-69	155.9	-172.5	0	0	0	0	0	114.5
306	A	32	Very low	35.3	Very low	100 Å²	100	128.9 Å²	128.9	83%	0.826	74%	0.736	S	S	*	*			trans	-139.8	151.7	166.5	0	0	0	0	0	110.2
307	D	33.4	Very low	34.5	Very low	165 Å²	165	134.5 Å²	134.5	88%	0.882	76%	0.759	S	S	*	*			trans	-77.5	171.5	-166	-80	-58.5	0	0	0	116.6
308	Y	30.7	Very low	33.8	Very low	209 Å²	209	136 Å²	136	82%	0.82	77%	0.769	S	S	*	*			trans	-144.3	155.6	172.1	-139.5	-109.6	0	0	0	107.2
309	P	51.4	Low	33.5	Very low	106 Å²	106	140.3 Å²	140.3	69%	0.688	78%	0.783	S	S	*	*			cis	-121.8	178.9	-7.6	21.2	1.9	0	0	0	113.9
310	D	30.5	Very low	33.2	Very low	153 Å²	153	145.7 Å²	145.7	82%	0.818	79%	0.79	S	S	*	*				-152.7	161.8	128.9	-149.8	0.8	0	0	0	112.1
311	Y	31.4	Very low	33.4	Very low	193 Å²	193	145.1 Å²	145.1	76%	0.757	79%	0.787	S	S	*	*			trans	-151.3	167	-179.3	-117	-108.9	0	0	0	107.9
312	P	43.9	Very low	33.2	Very low	105 Å²	105	145.3 Å²	145.3	68%	0.682	79%	0.788	S	S	*	*			cis	-135.6	175.1	12	40.6	-22.2	0	0	0	115.7
313	D	28.4	Very low	32.9	Very low	128 Å²	128	147 Å²	147	68%	0.684	79%	0.792	S	S	*	*				154.4	161.1	100.1	-150.5	2	0	0	0	114.8
314	H	32.5	Very low	33.1	Very low	149 Å²	149	154.1 Å²	154.1	69%	0.69	80%	0.797	S	S	*	*			trans	70.8	96.4	163.9	-84.5	-64.1	0	0	0	121.4
315	S	29.2	Very low	33.2	Very low	97 Å²	97	158.9 Å²	158.9	68%	0.678	80%	0.804	S	S	*	*				31.2	134.9	123.8	58.4	0	0	0	0	119.7
316	D	29.3	Very low	33	Very low	141 Å²	141	157 Å²	157	75%	0.754	80%	0.795	S	S	*	*			cis	-162	163.9	49.5	-169.1	24.7	0	0	0	114.7
317	H	32.3	Very low	32.8	Very low	170 Å²	170	158.2 Å²	158.2	79%	0.787	80%	0.797	S	S	*	*			trans	49.9	125.6	163.7	-106	-76.7	0	0	0	122.3
318	S	28.9	Very low	32.7	Very low	100 Å²	100	161.6 Å²	161.6	70%	0.699	80%	0.797	S	S	*	*			trans	-95.4	147.3	173.3	57.7	0	0	0	0	113.4
319	D	29.6	Very low	32.7	Very low	161 Å²	161	156.7 Å²	156.7	86%	0.861	79%	0.794	S	S	*	*			trans	-155.4	137.9	146.6	-118.8	-19.7	0	0	0	111.3
320	Y	29.9	Very low	31.6	Very low	223 Å²	223	161.3 Å²	161.3	88%	0.875	80%	0.799	S	S	*	*			trans	-144.5	164.1	178.9	-104.4	-35.8	0	0	0	109.8
321	P	42.4	Very low	31.7	Very low	116 Å²	116	160.9 Å²	160.9	75%	0.753	80%	0.796	S	S	*	*				-116.3	137.6	-129.7	36.4	-23.8	0	0	0	115.2
322	E	28.3	Very low	31.7	Very low	192 Å²	192	158.5 Å²	158.5	90%	0.897	80%	0.796	S	S	*	*			trans	-114.3	115.8	170.7	-70.8	-156.8	118.9	0	0	113.3
323	K	30	Very low	31	Very low	211 Å²	211	161.9 Å²	161.9	92%	0.917	81%	0.808	S	S	*	*			trans	-163.5	66.2	152.6	-112.2	159.7	-166.5	171.1	0	113.7
324	R	36.3	Very low	31	Very low	253 Å²	253	164.6 Å²	164.6	96%	0.955	82%	0.817	S	S	*	*			trans	-138.8	87.7	161.7	-83.5	-164.2	175.2	-125.9	4.5	112.8
325	R	33.3	Very low	30.9	Very low	258 Å²	258	163.3 Å²	163.3	97%	0.974	83%	0.825	S	S	*	*			trans	-167.1	152.1	163.6	-114	179.7	172.9	-161.6	-1.9	107.9
326	G	28.9	Very low	30.8	Very low	67 Å²	67	165.2 Å²	165.2	69%	0.691	83%	0.827	S	S	*	*			cis	-127.7	-157.6	-10.6	0	0	0	0	0	110.6
327	S	27.3	Very low	30.8	Very low	125 Å²	125	167.8 Å²	167.8	87%	0.874	83%	0.828	S	S	*	*			cis	-152.2	165.2	17.3	-65.4	0	0	0	0	112.8
328	R	32.5	Very low	30.6	Very low	236 Å²	236	166.2 Å²	166.2	89%	0.891	83%	0.826	S	S	*	*			trans	-126.1	-174.8	166.5	-77.4	-176	69.3	151.5	-0.1	109.3
329	S	31.2	Very low	30.9	Very low	106 Å²	106	170 Å²	170	74%	0.741	83%	0.829	S	S	*	*			trans	88	149.1	174.7	78.5	0	0	0	0	114.7
330	Y	28.1	Very low	31.1	Very low	203 Å²	203	167.6 Å²	167.6	80%	0.796	82%	0.822	S	S	*	*			cis	-144.9	148.6	26.6	-132.1	-84.3	0	0	0	114.8
331	L	32.4	Very low	31.2	Very low	144 Å²	144	162.6 Å²	162.6	75%	0.754	82%	0.817	S	S	*	*			trans	64.5	158.4	158.1	-94.8	169.1	0	0	0	124.1
332	D	30.6	Very low	30.6	Very low	144 Å²	144	164.5 Å²	164.5	77%	0.77	82%	0.819	S	S	*	*			trans	-95.4	166.6	179.9	-43.2	-91.5	0	0	0	112.7
333	D	29.8	Very low	30.4	Very low	175 Å²	175	160.7 Å²	160.7	94%	0.936	81%	0.814	S	S	*	*			trans	-156	156.7	150.3	-138.1	-25.8	0	0	0	111.4
334	E	28.7	Very low	30.3	Very low	185 Å²	185	160.6 Å²	160.6	86%	0.864	81%	0.809	S	S	*	*			trans	-116.7	128.2	-164.5	-169.6	-172.7	171.5	0	0	113.7
335	S	30.1	Very low	30	Very low	122 Å²	122	154.8 Å²	154.8	85%	0.853	80%	0.802	S	S	*	*			trans	-156.8	151.8	162.7	75.9	0	0	0	0	113.7
336	N	26.8	Very low	30.1	Very low	137 Å²	137	147.5 Å²	147.5	73%	0.733	79%	0.788	S	S	*	*			trans	-112.7	179.9	-167.7	-171.3	10.6	0	0	0	112.1
337	Y	28.5	Very low	30	Very low	195 Å²	195	152.9 Å²	152.9	77%	0.765	80%	0.795	S	S	*	*			trans	76.6	139.7	176.1	-73.2	-99.8	0	0	0	116.7
338	D	29.3	Very low	30.5	Very low	138 Å²	138	152.4 Å²	152.4	74%	0.738	79%	0.79	S	S	*	*			cis	-161.8	171.2	-19.4	-150.1	-14.4	0	0	0	111.1
339	K	34.4	Very low	30.1	Very low	179 Å²	179	149.8 Å²	149.8	78%	0.778	79%	0.79	S	S	*	*			trans	-118.7	120.3	-177.2	-178.7	-177.2	179.4	-178.5	0	114
340	P	34.6	Very low	30.1	Very low	110 Å²	110	151.8 Å²	151.8	71%	0.714	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-81.2	150.4	163.9	32.4	-31.8	0	0	0	112.3
341	P	30.8	Very low	30	Very low	118 Å²	118	151.2 Å²	151.2	77%	0.766	80%	0.802	S	S	*	*	P	Polyproline II helix	trans	-92.4	161.8	-170	36.1	-37	0	0	0	115.1
342	I	30.1	Very low	29.8	Very low	156 Å²	156	154.7 Å²	154.7	80%	0.8	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-70.2	139.3	163.1	-63.3	171.6	0	0	0	108.8	Y344	I342-Y344 HydrophobicContact CG2-CD2 4.27Å
343	S	24.6	Very low	29.9	Very low	112 Å²	112	154 Å²	154	78%	0.783	81%	0.808	S	S	*	*			trans	-121.8	139.1	169.6	-172.5	0	0	0	0	109.9
344	Y	28.1	Very low	29.9	Very low	209 Å²	209	152.2 Å²	152.2	82%	0.82	80%	0.798	S	S	*	*			trans	-143.6	104.2	-165.8	-144.2	-75.2	0	0	0	110.9	I342	I342-Y344 HydrophobicContact CG2-CD2 4.27Å
345	T	29.2	Very low	29.8	Very low	131 Å²	131	152 Å²	152	80%	0.804	80%	0.796	S	S	*	*			trans	-148.2	127.3	172.7	-29.4	0	0	0	0	110.9
346	P	37.1	Very low	29.6	Very low	105 Å²	105	152.2 Å²	152.2	68%	0.682	79%	0.788	S	S	*	*			trans	-108.5	178.6	-175.9	40.6	-35.4	0	0	0	114.3
347	Q	26.3	Very low	29.4	Very low	180 Å²	180	154.1 Å²	154.1	84%	0.841	79%	0.793	S	S	*	*			trans	128	156.5	158.2	-76.9	-167.2	27.4	0	0	114.4
348	P	37.3	Very low	29.4	Very low	116 Å²	116	149 Å²	149	75%	0.753	79%	0.791	S	S	*	*			cis	-134.8	-160.9	-30.2	37.3	-18.3	0	0	0	113.2
349	M	25.2	Very low	30.1	Very low	181 Å²	181	147.5 Å²	147.5	89%	0.892	79%	0.788	S	S	*	*			trans	-88.7	160.6	-173.1	-52.6	163.5	-175.2	0	0	114.8
350	V	30.5	Very low	29.7	Very low	147 Å²	147	149.4 Å²	149.4	89%	0.891	79%	0.792	S	S	*	*			trans	-142.8	152.6	156.5	-175.6	0	0	0	0	109.4
351	E	25	Very low	29.3	Very low	192 Å²	192	149.7 Å²	149.7	90%	0.897	80%	0.797	S	S	*	*			trans	-103.1	-179.4	-163.8	-64.8	-179.3	94.9	0	0	116.8
352	R	29.4	Very low	29.1	Very low	217 Å²	217	149.2 Å²	149.2	82%	0.819	80%	0.796	S	S	*	*			trans	-77.8	171.6	179.5	-57.8	175.5	168.6	-144.7	-1.2	113.3
353	P	32.1	Very low	28.8	Very low	129 Å²	129	147.3 Å²	147.3	84%	0.838	80%	0.797	S	S	*	*				-145.4	-173.7	95.7	34.4	-15.2	0	0	0	115.9
354	L	29.2	Very low	28.8	Very low	137 Å²	137	146.3 Å²	146.3	72%	0.717	79%	0.79	S	S	*	*			trans	-109.6	161.8	-175.6	-67.1	75.9	0	0	0	113
355	Q	27.1	Very low	28.8	Very low	180 Å²	180	141.2 Å²	141.2	84%	0.841	79%	0.785	S	S	*	*			trans	-169.6	143.1	139.9	-107.1	150.9	8.7	0	0	116.5
356	N	26	Very low	28.9	Very low	127 Å²	127	142.4 Å²	142.4	68%	0.679	78%	0.781	S	S	*	*			trans	22.7	150.6	132.5	-58.5	55.6	0	0	0	121.1
357	E	23	Very low	28.7	Very low	178 Å²	178	143.9 Å²	143.9	83%	0.832	78%	0.782	S	S	*	*			cis	-164.1	-162.2	-0.8	-124.1	176.8	110.6	0	0	114.2
358	A	27.6	Very low	28.7	Very low	87 Å²	87	140.7 Å²	140.7	72%	0.719	78%	0.775	S	S	*	*			trans	-119.1	-163.7	175.8	0	0	0	0	0	111.2
359	P	43.9	Very low	28.3	Very low	106 Å²	106	139.9 Å²	139.9	69%	0.688	77%	0.772	S	S	*	*			cis	-145.9	-172.2	-4.4	45.7	-25.8	0	0	0	118.2
360	Y	27.2	Very low	28.6	Very low	220 Å²	220	136.5 Å²	136.5	86%	0.863	77%	0.766	S	S	*	*			trans	54.6	130.6	147.3	-80.9	-62	0	0	0	126.9
361	S	25.7	Very low	28.7	Very low	115 Å²	115	136.1 Å²	136.1	80%	0.804	76%	0.764	S	S	*	*			trans	160.8	159.2	132.3	-77.3	0	0	0	0	113.1
362	S	25.9	Very low	28.9	Very low	108 Å²	108	130.3 Å²	130.3	76%	0.755	76%	0.756	S	S	*	*			cis	-174.6	168.2	-27.7	63.1	0	0	0	0	111.8
363	S	25.1	Very low	28.8	Very low	117 Å²	117	131.7 Å²	131.7	82%	0.818	76%	0.761	S	S	*	*			trans	72.8	151.1	155.5	-156.1	0	0	0	0	120.7
364	S	24.5	Very low	29.3	Very low	90 Å²	90	131.1 Å²	131.1	63%	0.629	76%	0.758	S	S	*	*			cis	-172.8	-178.4	-27.7	-168.2	0	0	0	0	112.1
365	S	28.5	Very low	29.8	Very low	102 Å²	102	134.5 Å²	134.5	71%	0.713	77%	0.767	S	S	*	*			trans	80	137.3	172.6	69.2	0	0	0	0	119.2
366	E	30.3	Very low	29.9	Very low	156 Å²	156	135.8 Å²	135.8	73%	0.729	77%	0.769	S	S	*	*			cis	102.2	151	19	-68.3	168.8	97.6	0	0	114.2
367	I	32.5	Very low	30.2	Very low	137 Å²	137	141.2 Å²	141.2	70%	0.703	78%	0.78	S	S	*	*			cis	-166.7	158.5	2.7	-117.9	162.2	0	0	0	107.3
368	T	27.7	Very low	30.8	Very low	113 Å²	113	144.7 Å²	144.7	69%	0.693	79%	0.786	S	S	*	*			cis	-161.4	172	-30.1	36.9	0	0	0	0	110.5
369	S	27.4	Very low	31.2	Very low	98 Å²	98	145.3 Å²	145.3	69%	0.685	79%	0.791	S	S	*	*			trans	58.1	109	150.5	59.9	0	0	0	0	121.7
370	S	31.3	Very low	30.9	Very low	110 Å²	110	143.7 Å²	143.7	77%	0.769	79%	0.793	S	S	*	*				94.1	159.3	84.1	82.5	0	0	0	0	114.7
371	T	32.5	Very low	30.9	Very low	139 Å²	139	144.4 Å²	144.4	85%	0.853	79%	0.794	S	S	*	*			cis	-140.3	-147.6	7.9	68.5	0	0	0	0	111.7
372	G	29.5	Very low	31.3	Very low	71 Å²	71	144.1 Å²	144.1	73%	0.732	79%	0.79	S	S	*	*			trans	108.7	78.4	146.6	0	0	0	0	0	122.1
373	R	28.8	Very low	31.8	Very low	245 Å²	245	150.7 Å²	150.7	93%	0.925	80%	0.798	S	S	*	*			trans	-56	170.3	174.9	-63	174.9	179.3	-171.3	0.5	116.6
374	P	41.1	Very low	32.2	Very low	117 Å²	117	155.9 Å²	155.9	76%	0.76	80%	0.8	S	S	*	*			cis	-139.1	155.5	-9.7	32.7	-11.2	0	0	0	119.1
375	K	39.2	Very low	32.8	Very low	209 Å²	209	156.5 Å²	156.5	91%	0.909	81%	0.81	S	S	*	*			trans	27.9	123.7	147.8	-66.5	-176.5	176.6	180	0	122.7
376	K	30.1	Very low	32.9	Very low	206 Å²	206	158 Å²	158	90%	0.896	81%	0.811	S	S	*	*				-152.7	142.3	129.5	-115.9	171	-173.7	173.9	0	112.6
377	R	32.9	Very low	33.4	Very low	242 Å²	242	154.2 Å²	154.2	91%	0.913	81%	0.813	S	S	*	*			trans	21.4	124.1	169.1	-58.8	177.1	77.6	171.7	3.5	119.8
378	R	34.2	Very low	33.4	Very low	251 Å²	251	155.6 Å²	155.6	95%	0.947	82%	0.816	S	S	*	*			trans	-76.2	146.4	170.8	-74.5	178.4	171.6	163.7	-4	112.6
379	A	35.9	Very low	33.5	Very low	99 Å²	99	157 Å²	157	82%	0.818	82%	0.82	S	S	*	*			trans	-99.9	178.6	153.7	0	0	0	0	0	110.2
380	G	37.8	Very low	33.8	Very low	72 Å²	72	162.3 Å²	162.3	74%	0.742	83%	0.826	S	S	*	*	P	Polyproline II helix	trans	-58.5	148.7	-172.6	0	0	0	0	0	115.3	P382	G380-P382 VanDerWaalsContact O-CD 3.31Å; G380-P382 WeakPolarHBondContact O-CD 3.44Å
381	R	27.8	Very low	33.7	Very low	236 Å²	236	164.6 Å²	164.6	89%	0.891	83%	0.83	S	S	*	*	P	Polyproline II helix	trans	-65.4	117.8	-178.9	177.3	-175.1	-179	-169.9	2.9	111.2	R383	R381-R383 PolarHBondContact O-N 2.89Å
382	P	34.5	Very low	34	Very low	109 Å²	109	163 Å²	163	71%	0.708	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-65.7	131.9	164.7	-15.7	31	0	0	0	109.3	G380 R384	G380-P382 VanDerWaalsContact O-CD 3.31Å; G380-P382 WeakPolarHBondContact O-CD 3.44Å; P382-R384 PolarHBondContact O-N 3.04Å
383	R	36.5	Very low	34.2	Very low	245 Å²	245	166.5 Å²	166.5	93%	0.925	82%	0.822	S	S	*	*	P	Polyproline II helix	trans	-69.2	119.9	161.4	-97.9	-176.8	165.9	114.5	-2.7	107	R381	R381-R383 PolarHBondContact O-N 2.89Å
384	R	32.1	Very low	34.7	Very low	226 Å²	226	164.5 Å²	164.5	85%	0.853	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-63.8	145.4	170.9	-75.3	-175.7	172.6	133.9	-2.3	109.2	P382	P382-R384 PolarHBondContact O-N 3.04Å
385	A	38.2	Very low	34.3	Very low	103 Å²	103	166.9 Å²	166.9	85%	0.851	82%	0.822	S	S	*	*	P	Polyproline II helix	trans	-71.7	125.6	148.8	0	0	0	0	0	107
386	D	30.5	Very low	34.2	Very low	135 Å²	135	162.5 Å²	162.5	72%	0.722	82%	0.818	S	S	*	*			trans	-123.7	121.5	154.1	-111.4	-49.3	0	0	0	104.9
387	G	40.8	Very low	34.5	Very low	75 Å²	75	156 Å²	156	77%	0.773	80%	0.798	S	S	*	*			trans	-92.9	103	176.6	0	0	0	0	0	108.3
388	Q	33	Very low	34.7	Very low	166 Å²	166	147.8 Å²	147.8	78%	0.776	79%	0.789	S	S	*	*			trans	-119.6	101.6	167.5	-74.1	-176.1	-20.5	0	0	108.1
389	D	29	Very low	34.9	Very low	144 Å²	144	139.2 Å²	139.2	77%	0.77	76%	0.762	S	S	*	*			trans	53.8	124.5	148.4	-49.7	-39.4	0	0	0	120.1	D391	D389-D391 PolarHBondContact O-N 3.39Å; D389-D391 VanDerWaalsContact O-N 3.15Å
390	Y	34	Very low	35.1	Very low	208 Å²	208	142.9 Å²	142.9	82%	0.816	76%	0.763	S	S	*	*			trans	-81.4	82.1	175.2	-83.8	-109.3	0	0	0	110.4	T392	Y390-T392 HydrophobicContact CD1-CG2 3.76Å; Y390-T392 PolarHBondContact O-N 3.39Å
391	D	30.2	Very low	35.4	Very low	159 Å²	159	143.7 Å²	143.7	85%	0.85	75%	0.749	S	S	*	*			trans	-73.1	64.3	155.4	-80.7	-25.4	0	0	0	109.5	D389 D393	D389-D391 PolarHBondContact O-N 3.39Å; D389-D391 VanDerWaalsContact O-N 3.15Å; D391-D393 PolarHBondContact O-N 3.49Å
392	T	36.8	Very low	36.3	Very low	106 Å²	106	139.1 Å²	139.1	65%	0.65	74%	0.743	S	S	*	*			trans	-81.4	30.1	170.7	35.1	0	0	0	0	112.8	Y390	Y390-T392 HydrophobicContact CD1-CG2 3.76Å; Y390-T392 PolarHBondContact O-N 3.39Å
393	D	34.5	Very low	37	Very low	143 Å²	143	141.3 Å²	141.3	77%	0.765	75%	0.748	S	S	*	*			trans	-127.3	61.5	-177.3	-85	-46.9	0	0	0	112.2	D391	D391-D393 PolarHBondContact O-N 3.49Å
394	Y	39.7	Very low	37.8	Very low	204 Å²	204	133.1 Å²	133.1	80%	0.8	72%	0.723	S	S	*	*			trans	-151.6	37.5	153.6	-130.3	-84.1	0	0	0	114.8
395	N	32.7	Very low	39.5	Very low	166 Å²	166	127 Å²	127	89%	0.888	71%	0.707	S	S	*	*	S	Bend	trans	-104.8	22.7	166	-151.6	100.6	0	0	0	111.9
396	S	37.2	Very low	41.6	Very low	118 Å²	118	123 Å²	123	83%	0.825	67%	0.67	S	S	*	*			trans	-124	42.9	175.2	-170.9	0	0	0	0	111.7
397	S	35.5	Very low	43.8	Very low	68 Å²	68	121.1 Å²	121.1	48%	0.476	66%	0.66	S	S	.	*			trans	-117.3	110.6	150.2	-179.8	0	0	0	0	104.5	D399	S397-D399 PolarHBondContact OG-N 2.85Å
398	G	37.7	Very low	45.7	Very low	71 Å²	71	121.8 Å²	121.8	73%	0.732	65%	0.653	S	S	*	*			cis	72.1	8.3	20.8	0	0	0	0	0	112	E400	G398-E400 PolarHBondContact O-N 3.44Å
399	D	39	Very low	48.2	Very low	71 Å²	71	118.7 Å²	118.7	38%	0.38	64%	0.639	S	S	.	*			trans	-88.8	57.6	149.5	-152	34.3	0	0	0	105.9	S397 L401 R488	S397-D399 PolarHBondContact OG-N 2.85Å; D399-L401 PolarHBondContact O-N 3Å; D399-R488 IonicContact OD1-NH1 3.24Å; D399-R488 PolarHBondContact OD1-NH1 3.36Å; D399-R488 VanDerWaalsContact OD1-NH1 3.1Å; D399-R488 WeakPolarHBondContact OD2-CD 3.41Å; D399-R488 IonicContact OD2-CZ 3.75Å; D399-R488 IonicContact OD2-NE 2.75Å; D399-R488 IonicContact OD2-NH1 3.1Å; D399-R488 PolarHBondContact OD2-NH1 2.93Å
400	E	39.3	Very low	51	Low	176 Å²	176	112.2 Å²	112.2	82%	0.822	60%	0.604	S	S	*	*			trans	-55.7	106.8	145.5	-72.4	179.7	158.6	0	0	103.3	G398 D402	G398-E400 PolarHBondContact O-N 3.44Å; E400-D402 PolarHBondContact O-N 3.03Å
401	L	44.9	Very low	53.6	Low	89 Å²	89	104.7 Å²	104.7	47%	0.466	58%	0.581	S	S	.	*			trans	-71	86.1	171.9	-73.8	173.5	0	0	0	105.2	D399 D403 K491	D399-L401 PolarHBondContact O-N 3Å; L401-D403 PolarHBondContact O-N 2.86Å; L401-K491 HydrophobicContact CD1-CD 4.39Å
402	D	45.5	Very low	56.5	Low	140 Å²	140	101.3 Å²	101.3	75%	0.749	57%	0.567	S	S	*	*			trans	-19.2	124.1	173.6	-168.7	19	0	0	0	110.5	E400 N404	E400-D402 PolarHBondContact O-N 3.03Å; D402-N404 WeakPolarHBondContact O-CA 3.14Å; D402-N404 PolarHBondContact O-N 3.15Å; D402-N404 PolarHBondContact O-ND2 3.25Å
403	D	49.4	Very low	59.1	Low	154 Å²	154	96.3 Å²	96.3	82%	0.824	54%	0.536	S	S	*	.			trans	-50.1	102.4	-167.6	-77.5	-56.9	0	0	0	109.4	L401 D405	L401-D403 PolarHBondContact O-N 2.86Å; D403-D405 VanDerWaalsContact C-N 3.28Å; D403-D405 PolarHBondContact O-N 2.99Å
404	N	54.9	Low	61.6	Low	74 Å²	74	92.6 Å²	92.6	40%	0.396	53%	0.526	S	S	.	.			trans	-73.8	91.6	-168	-86	-117.6	0	0	0	106.5	D402 F406 Y492	D402-N404 WeakPolarHBondContact O-CA 3.14Å; D402-N404 PolarHBondContact O-N 3.15Å; D402-N404 PolarHBondContact O-ND2 3.25Å; N404-F406 HydrophobicContact CB-CD2 3.99Å; N404-F406 HydrophobicContact CB-CE1 4.31Å; N404-F406 HydrophobicContact CB-CE2 3.46Å; N404-F406 VanDerWaalsContact CB-CE2 3.46Å; N404-F406 HydrophobicContact CB-CZ 3.66Å; N404-F406 WeakPolarHBondContact O-CD2 3.45Å; N404-F406 PolarHBondContact O-N 3.07Å; N404-Y492 WeakPolarHBondContact OD1-CD2 3.14Å; N404-Y492 WeakPolarHBondContact OD1-CE2 3.41Å
405	D	66.8	Low	64	Low	97 Å²	97	87.8 Å²	87.8	52%	0.519	51%	0.514	S	S	.	.			trans	-72.9	67	-174.1	-170.2	-6.9	0	0	0	110.6	D403 D407 S408 E409	D403-D405 VanDerWaalsContact C-N 3.28Å; D403-D405 PolarHBondContact O-N 2.99Å; D405-D407 PolarHBondContact O-N 3.22Å; D405-D407 WeakPolarHBondContact OD1-CB 3.35Å; D405-D407 PolarHBondContact OD1-N 3.06Å; D405-S408 WeakPolarHBondContact O-CB 3.3Å; D405-S408 PolarHBondContact O-N 3.46Å; D405-S408 PolarHBondContact O-OG 3.35Å; D405-S408 PolarHBondContact OD1-N 3.02Å; D405-E409 PolarHBondContact O-N 3.3Å
406	F	81.8	Confident	66.8	Low	18 Å²	18	86 Å²	86	8%	0.079	50%	0.5	C	S	.	.	H	α-helix	trans	-66.2	-14.3	172.1	-57.3	-65.1	0	0	0	111.6	N404 S408 F410 Y492 H495 K496 H499	N404-F406 HydrophobicContact CB-CD2 3.99Å; N404-F406 HydrophobicContact CB-CE1 4.31Å; N404-F406 HydrophobicContact CB-CE2 3.46Å; N404-F406 VanDerWaalsContact CB-CE2 3.46Å; N404-F406 HydrophobicContact CB-CZ 3.66Å; N404-F406 WeakPolarHBondContact O-CD2 3.45Å; N404-F406 PolarHBondContact O-N 3.07Å; F406-S408 PolarHBondContact O-N 2.99Å; F406-F410 HydrophobicContact CD1-CD2 4.47Å; F406-F410 CarbonylContact O-C 3.54Å; F406-F410 VanDerWaalsContact O-CA 3.32Å; F406-F410 WeakPolarHBondContact O-CA 3.36Å; F406-F410 WeakPolarHBondContact O-CB 3.49Å; F406-F410 PolarHBondContact O-N 3.34Å; F406-Y492 HydrophobicContact CE1-CD2 4.49Å; F406-Y492 AromaticContact CE1-CE2 3.71Å; F406-Y492 HydrophobicContact CE1-CE2 3.71Å; F406-Y492 AromaticContact CE1-CZ 3.95Å; F406-Y492 HydrophobicContact CZ-CD2 4.07Å; F406-Y492 AromaticContact CZ-CE2 3.74Å; F406-Y492 HydrophobicContact CZ-CE2 3.74Å; F406-H495 HydrophobicContact CE2-CB 3.81Å; F406-H495 HydrophobicContact CZ-CB 4.4Å; F406-K496 HydrophobicContact CD1-CB 4.31Å; F406-K496 HydrophobicContact CD1-CG 4.22Å; F406-K496 HydrophobicContact CE1-CB 3.66Å; F406-K496 HydrophobicContact CE1-CD 4.44Å; F406-K496 HydrophobicContact CE1-CG 3.9Å; F406-K496 HydrophobicContact CZ-CB 3.77Å; F406-H499 HydrophobicContact CB-CB 4.17Å; F406-H499 WeakPolarHBondContact CB-CD2 3.41Å; F406-H499 HydrophobicContact CD2-CB 4.46Å; F406-H499 PolarHBondContact O-CD2 3.16Å; F406-H499 PolarHBondContact O-NE2 2.99Å
407	D	78	Confident	69.3	Low	96 Å²	96	88.6 Å²	88.6	51%	0.513	50%	0.499	S	S	.	.	H	α-helix	trans	-67.2	-24.5	168.6	-70.1	-50.4	0	0	0	110.9	D405 P411 H499	D405-D407 PolarHBondContact O-N 3.22Å; D405-D407 WeakPolarHBondContact OD1-CB 3.35Å; D405-D407 PolarHBondContact OD1-N 3.06Å; D407-P411 WeakPolarHBondContact O-CA 3.28Å; D407-H499 IonicContact OD1-CE1 2.63Å; D407-H499 PolarHBondContact OD1-CE1 3.05Å; D407-H499 IonicContact OD1-NE2 3.98Å
408	S	81.1	Confident	72	Confident	89 Å²	89	87.9 Å²	87.9	62%	0.622	49%	0.488	S	S	*	.	H	α-helix	trans	-84.2	-36	172.9	79.7	0	0	0	0	114.8	D405 F406	D405-S408 WeakPolarHBondContact O-CB 3.3Å; D405-S408 PolarHBondContact O-N 3.46Å; D405-S408 PolarHBondContact O-OG 3.35Å; D405-S408 PolarHBondContact OD1-N 3.02Å; F406-S408 PolarHBondContact O-N 2.99Å
409	E	83.8	Confident	74.6	Confident	102 Å²	102	86.2 Å²	86.2	48%	0.477	46%	0.46	S	S	.	.	H	α-helix	trans	-84.6	-35.4	179.4	-166.5	-177.2	-168.2	0	0	112.1	D405	D405-E409 PolarHBondContact O-N 3.3Å
410	F	88.6	Confident	77.1	Confident	7 Å²	7	86.3 Å²	86.3	3%	0.031	46%	0.46	C	S	.	.	S	Bend	trans	-128.8	73	179.9	-59.4	-81.3	0	0	0	110.1	F406 Y422 E425 K496 H499 I500	F406-F410 HydrophobicContact CD1-CD2 4.47Å; F406-F410 CarbonylContact O-C 3.54Å; F406-F410 VanDerWaalsContact O-CA 3.32Å; F406-F410 WeakPolarHBondContact O-CA 3.36Å; F406-F410 WeakPolarHBondContact O-CB 3.49Å; F406-F410 PolarHBondContact O-N 3.34Å; F410-Y422 HydrophobicContact CB-CD2 4.37Å; F410-Y422 HydrophobicContact CB-CE2 3.73Å; F410-Y422 HydrophobicContact CD1-CD1 4.47Å; F410-Y422 HydrophobicContact CD1-CD2 4.01Å; F410-Y422 HydrophobicContact CD1-CE1 4.39Å; F410-Y422 AromaticContact CD1-CE2 3.92Å; F410-Y422 HydrophobicContact CD1-CE2 3.92Å; F410-Y422 HydrophobicContact CD1-CG 4.33Å; F410-Y422 HydrophobicContact CG-CE2 4.33Å; F410-E425 HydrophobicContact CE1-CG 4.27Å; F410-E425 HydrophobicContact CZ-CG 4.32Å; F410-K496 HydrophobicContact CE2-CD 4.31Å; F410-K496 HydrophobicContact CE2-CG 4.23Å; F410-H499 PolarHBondContact O-NE2 3.39Å; F410-I500 HydrophobicContact CB-CG1 4.44Å; F410-I500 HydrophobicContact CD1-CD1 3.97Å; F410-I500 HydrophobicContact CD1-CG1 3.83Å; F410-I500 HydrophobicContact CD2-CD1 4.28Å; F410-I500 HydrophobicContact CD2-CG1 4.12Å; F410-I500 HydrophobicContact CE1-CD1 3.74Å; F410-I500 HydrophobicContact CE1-CG1 4.14Å; F410-I500 HydrophobicContact CE2-CD1 4.08Å; F410-I500 HydrophobicContact CE2-CG1 4.42Å; F410-I500 HydrophobicContact CG-CD1 4.25Å; F410-I500 HydrophobicContact CG-CG1 3.84Å; F410-I500 HydrophobicContact CZ-CD1 3.82Å; F410-I500 HydrophobicContact CZ-CG1 4.45Å
411	P	88.5	Confident	79.6	Confident	51 Å²	51	81.1 Å²	81.1	33%	0.331	44%	0.444	S	S	.	.			trans	-63.1	171	177.4	26.5	-36.2	0	0	0	113.4	D407 I413 Y422	D407-P411 WeakPolarHBondContact O-CA 3.28Å; P411-I413 PolarHBondContact O-N 3.35Å; P411-Y422 VanDerWaalsContact CD-OH 3.31Å; P411-Y422 WeakPolarHBondContact CD-OH 3.39Å; P411-Y422 PolarHBondContact O-OH 3.46Å; P411-Y422 VanDerWaalsContact O-OH 3.07Å
412	P	90.3	Very high	81.9	Confident	88 Å²	88	77.8 Å²	77.8	57%	0.571	43%	0.425	S	S	*	.			trans	-62.5	107	177.2	-24.3	35.5	0	0	0	112.7	A414 M503	P412-A414 PolarHBondContact O-N 3.16Å; P412-M503 HydrophobicContact CB-SD 4.37Å; P412-M503 HydrophobicContact CG-SD 4.26Å
413	I	92.1	Very high	84.1	Confident	0 Å²	0	72.1 Å²	72.1	0%	0	39%	0.394	C	S	.	.			trans	-45.3	134.4	-176.4	-60	162	0	0	0	112.2	P411 N415 E418 R419 Y422 M503 V504 Y507 R510	P411-I413 PolarHBondContact O-N 3.35Å; I413-N415 WeakPolarHBondContact CG2-O 3.3Å; I413-E418 WeakPolarHBondContact CA-OE2 3.25Å; I413-E418 HydrophobicContact CG1-CG 4.35Å; I413-E418 HydrophobicContact CG2-CB 4.16Å; I413-E418 HydrophobicContact CG2-CG 4.09Å; I413-R419 HydrophobicContact CG2-CB 4.06Å; I413-Y422 HydrophobicContact CD1-CD2 3.62Å; I413-Y422 HydrophobicContact CD1-CE2 4Å; I413-Y422 HydrophobicContact CD1-CG 4.05Å; I413-Y422 HydrophobicContact CG1-CD2 3.66Å; I413-Y422 HydrophobicContact CG1-CE1 4.44Å; I413-Y422 HydrophobicContact CG1-CE2 3.5Å; I413-Y422 VanDerWaalsContact CG1-CE2 3.5Å; I413-Y422 HydrophobicContact CG1-CG 4.18Å; I413-M503 HydrophobicContact CD1-CB 4.01Å; I413-M503 HydrophobicContact CG1-CB 4.28Å; I413-V504 HydrophobicContact CD1-CB 4.33Å; I413-V504 HydrophobicContact CD1-CG2 3.73Å; I413-Y507 HydrophobicContact CB-CD2 4.04Å; I413-Y507 HydrophobicContact CB-CG 4.27Å; I413-Y507 HydrophobicContact CG2-CD1 4.5Å; I413-Y507 HydrophobicContact CG2-CD2 3.6Å; I413-Y507 HydrophobicContact CG2-CE2 4.03Å; I413-Y507 HydrophobicContact CG2-CG 3.86Å; I413-Y507 WeakPolarHBondContact O-CD2 3.44Å; I413-R510 PolarHBondContact O-NH1 3.44Å; I413-R510 PolarHBondContact O-NH2 2.92Å
414	A	86.9	Confident	86.3	Confident	65 Å²	65	71.8 Å²	71.8	54%	0.537	39%	0.387	S	S	.	.			trans	-106.8	-31.6	177	0	0	0	0	0	113.5	P412 E418 Y507	P412-A414 PolarHBondContact O-N 3.16Å; A414-E418 PolarHBondContact N-OE2 3.16Å; A414-Y507 WeakPolarHBondContact O-CE2 3.33Å
415	N	90.9	Very high	88.1	Confident	103 Å²	103	70.3 Å²	70.3	55%	0.551	38%	0.378	S	S	*	.	S	Bend	trans	-130.9	152.8	-169.7	-62.8	-61.9	0	0	0	113.6	I413 Q417 E418 R419	I413-N415 WeakPolarHBondContact CG2-O 3.3Å; N415-Q417 VanDerWaalsContact C-N 3.3Å; N415-Q417 PolarHBondContact O-N 2.99Å; N415-E418 HydrophobicContact CB-CB 4.47Å; N415-E418 WeakPolarHBondContact O-CB 3.22Å; N415-E418 PolarHBondContact O-N 3.11Å; N415-E418 VanDerWaalsContact O-N 3.08Å; N415-R419 PolarHBondContact O-N 3.46Å
416	E	90.4	Very high	89.4	Confident	129 Å²	129	66 Å²	66	60%	0.603	35%	0.354	S	S	*	.	H	α-helix	trans	-61.8	-34.5	178.3	-169	-171.9	172.4	0	0	113.2	E418 R419 N420 Y507	E416-E418 VanDerWaalsContact C-N 3.31Å; E416-E418 PolarHBondContact O-N 3.47Å; E416-R419 WeakPolarHBondContact O-CB 3.47Å; E416-R419 PolarHBondContact O-N 3.02Å; E416-N420 VanDerWaalsContact O-CG 3.3Å; E416-N420 PolarHBondContact O-N 2.95Å; E416-N420 PolarHBondContact O-ND2 3.31Å; E416-Y507 PolarHBondContact N-OH 3Å
417	Q	91.2	Very high	89.9	Confident	173 Å²	173	67 Å²	67	81%	0.808	36%	0.361	S	S	*	.	H	α-helix	trans	-62.5	-39.6	174.6	-66.8	180	-12.3	0	0	111.9	N415 S421	N415-Q417 VanDerWaalsContact C-N 3.3Å; N415-Q417 PolarHBondContact O-N 2.99Å; Q417-S421 PolarHBondContact O-N 3.36Å; Q417-S421 VanDerWaalsContact O-N 3.09Å
418	E	90.8	Very high	90.7	Very high	52 Å²	52	68.8 Å²	68.8	24%	0.243	36%	0.36	C	S	.	.	H	α-helix	trans	-69.5	-45.1	176.4	179.8	-178.4	-153.4	0	0	110.5	I413 A414 N415 E416 N420 S421 Y422	I413-E418 WeakPolarHBondContact CA-OE2 3.25Å; I413-E418 HydrophobicContact CG1-CG 4.35Å; I413-E418 HydrophobicContact CG2-CB 4.16Å; I413-E418 HydrophobicContact CG2-CG 4.09Å; A414-E418 PolarHBondContact N-OE2 3.16Å; N415-E418 HydrophobicContact CB-CB 4.47Å; N415-E418 WeakPolarHBondContact O-CB 3.22Å; N415-E418 PolarHBondContact O-N 3.11Å; N415-E418 VanDerWaalsContact O-N 3.08Å; E416-E418 VanDerWaalsContact C-N 3.31Å; E416-E418 PolarHBondContact O-N 3.47Å; E418-N420 VanDerWaalsContact C-N 3.29Å; E418-N420 PolarHBondContact O-N 2.97Å; E418-S421 WeakPolarHBondContact O-CB 3.5Å; E418-S421 PolarHBondContact O-N 3.11Å; E418-S421 VanDerWaalsContact O-N 3.11Å; E418-Y422 HydrophobicContact CG-CD1 3.88Å; E418-Y422 HydrophobicContact CG-CE1 3.33Å; E418-Y422 WeakPolarHBondContact O-CD1 3.28Å; E418-Y422 PolarHBondContact O-N 2.9Å; E418-Y422 PolarHBondContact OE1-OH 2.93Å
419	R	92.4	Very high	91.2	Very high	37 Å²	37	64.7 Å²	64.7	14%	0.14	33%	0.331	C	S	.	.	H	α-helix	trans	-50.6	-47.3	171.8	-174.3	-148.6	178.1	-102.8	-1.9	112.3	I413 N415 E416 Y422 K423 V504 Y507 D508	I413-R419 HydrophobicContact CG2-CB 4.06Å; N415-R419 PolarHBondContact O-N 3.46Å; E416-R419 WeakPolarHBondContact O-CB 3.47Å; E416-R419 PolarHBondContact O-N 3.02Å; R419-Y422 PolarHBondContact O-N 3.19Å; R419-K423 PolarHBondContact O-N 2.82Å; R419-V504 HydrophobicContact CG-CG1 4.03Å; R419-Y507 HydrophobicContact CB-CD1 4.11Å; R419-Y507 HydrophobicContact CB-CE1 4.25Å; R419-Y507 HydrophobicContact CG-CD1 3.92Å; R419-Y507 HydrophobicContact CG-CE1 4.38Å; R419-D508 IonicContact CZ-OD1 3.59Å; R419-D508 IonicContact CZ-OD2 3.61Å; R419-D508 IonicContact NE-OD1 3.98Å; R419-D508 PolarHBondContact NE-OD1 3.12Å; R419-D508 IonicContact NE-OD2 3.5Å; R419-D508 IonicContact NH2-OD1 2.66Å; R419-D508 PolarHBondContact NH2-OD1 3.05Å; R419-D508 IonicContact NH2-OD2 2.75Å; R419-D508 PolarHBondContact NH2-OD2 3.21Å
420	N	91.7	Very high	91.7	Very high	72 Å²	72	61 Å²	61	39%	0.385	31%	0.314	S	S	.	.	H	α-helix	trans	-72.1	-32.1	-178.2	-67.4	-21.7	0	0	0	112.1	E416 E418 K423 Q424	E416-N420 VanDerWaalsContact O-CG 3.3Å; E416-N420 PolarHBondContact O-N 2.95Å; E416-N420 PolarHBondContact O-ND2 3.31Å; E418-N420 VanDerWaalsContact C-N 3.29Å; E418-N420 PolarHBondContact O-N 2.97Å; N420-K423 PolarHBondContact O-N 3.35Å; N420-Q424 PolarHBondContact O-N 3.39Å
421	S	92.5	Very high	91.9	Very high	68 Å²	68	65.9 Å²	65.9	48%	0.476	34%	0.34	S	S	.	.	H	α-helix	trans	-63.2	-45.4	168.9	-168.4	0	0	0	0	111.9	Q417 E418 K423 Q424 E425	Q417-S421 PolarHBondContact O-N 3.36Å; Q417-S421 VanDerWaalsContact O-N 3.09Å; E418-S421 WeakPolarHBondContact O-CB 3.5Å; E418-S421 PolarHBondContact O-N 3.11Å; E418-S421 VanDerWaalsContact O-N 3.11Å; S421-K423 VanDerWaalsContact C-N 3.34Å; S421-K423 PolarHBondContact O-N 2.96Å; S421-Q424 PolarHBondContact O-N 2.7Å; S421-E425 PolarHBondContact O-N 3.38Å
422	Y	92.4	Very high	92.2	Very high	18 Å²	18	66.6 Å²	66.6	7%	0.071	34%	0.339	C	S	.	.	H	α-helix	trans	-63.9	-38.1	177.8	-79.6	44.3	0	0	0	111	F410 P411 I413 E418 R419 F426 I500 M503	F410-Y422 HydrophobicContact CB-CD2 4.37Å; F410-Y422 HydrophobicContact CB-CE2 3.73Å; F410-Y422 HydrophobicContact CD1-CD1 4.47Å; F410-Y422 HydrophobicContact CD1-CD2 4.01Å; F410-Y422 HydrophobicContact CD1-CE1 4.39Å; F410-Y422 AromaticContact CD1-CE2 3.92Å; F410-Y422 HydrophobicContact CD1-CE2 3.92Å; F410-Y422 HydrophobicContact CD1-CG 4.33Å; F410-Y422 HydrophobicContact CG-CE2 4.33Å; P411-Y422 VanDerWaalsContact CD-OH 3.31Å; P411-Y422 WeakPolarHBondContact CD-OH 3.39Å; P411-Y422 PolarHBondContact O-OH 3.46Å; P411-Y422 VanDerWaalsContact O-OH 3.07Å; I413-Y422 HydrophobicContact CD1-CD2 3.62Å; I413-Y422 HydrophobicContact CD1-CE2 4Å; I413-Y422 HydrophobicContact CD1-CG 4.05Å; I413-Y422 HydrophobicContact CG1-CD2 3.66Å; I413-Y422 HydrophobicContact CG1-CE1 4.44Å; I413-Y422 HydrophobicContact CG1-CE2 3.5Å; I413-Y422 VanDerWaalsContact CG1-CE2 3.5Å; I413-Y422 HydrophobicContact CG1-CG 4.18Å; E418-Y422 HydrophobicContact CG-CD1 3.88Å; E418-Y422 HydrophobicContact CG-CE1 3.33Å; E418-Y422 WeakPolarHBondContact O-CD1 3.28Å; E418-Y422 PolarHBondContact O-N 2.9Å; E418-Y422 PolarHBondContact OE1-OH 2.93Å; R419-Y422 PolarHBondContact O-N 3.19Å; Y422-F426 WeakPolarHBondContact O-CB 3.37Å; Y422-F426 PolarHBondContact O-N 3.3Å; Y422-I500 HydrophobicContact CD2-CG2 4.36Å; Y422-I500 WeakPolarHBondContact O-CG2 3.5Å; Y422-M503 HydrophobicContact CD2-CB 4.25Å; Y422-M503 HydrophobicContact CE2-CB 4.22Å
423	K	92.4	Very high	92.3	Very high	21 Å²	21	64 Å²	64	9%	0.091	32%	0.318	C	S	.	.	H	α-helix	trans	-62.9	-46.2	171.3	178.5	167.8	-171.3	-73.1	0	112.1	W292 V296 S297 R419 N420 S421 E425 F426 D427	W292-K423 HydrophobicContact CH2-CB 4.24Å; W292-K423 HydrophobicContact CH2-CD 3.79Å; W292-K423 HydrophobicContact CH2-CG 3.81Å; W292-K423 HydrophobicContact CZ2-CD 4.45Å; W292-K423 HydrophobicContact CZ3-CD 4.25Å; W292-K423 HydrophobicContact CZ3-CG 4.21Å; V296-K423 HydrophobicContact CB-CD 4.34Å; V296-K423 HydrophobicContact CG1-CD 3.7Å; V296-K423 WeakPolarHBondContact O-CE 3.34Å; V296-K423 PolarHBondContact O-NZ 3.44Å; S297-K423 PolarHBondContact OG-NZ 2.86Å; R419-K423 PolarHBondContact O-N 2.82Å; N420-K423 PolarHBondContact O-N 3.35Å; S421-K423 VanDerWaalsContact C-N 3.34Å; S421-K423 PolarHBondContact O-N 2.96Å; K423-E425 VanDerWaalsContact C-N 3.28Å; K423-E425 PolarHBondContact O-N 3.22Å; K423-F426 WeakPolarHBondContact O-CB 3.36Å; K423-F426 PolarHBondContact O-N 2.93Å; K423-D427 WeakPolarHBondContact CG-OD2 3.42Å; K423-D427 IonicContact NZ-OD1 3.95Å; K423-D427 IonicContact NZ-OD2 2.75Å; K423-D427 PolarHBondContact NZ-OD2 3.35Å; K423-D427 WeakPolarHBondContact O-CB 3.42Å; K423-D427 VanDerWaalsContact O-CG 3.3Å; K423-D427 PolarHBondContact O-N 3.08Å
424	Q	94	Very high	92.3	Very high	148 Å²	148	67.7 Å²	67.7	69%	0.692	33%	0.334	S	S	*	.	H	α-helix	trans	-61.8	-37.2	-179.9	-172.9	178.3	3.4	0	0	112.1	N420 S421 R428	N420-Q424 PolarHBondContact O-N 3.39Å; S421-Q424 PolarHBondContact O-N 2.7Å; Q424-R428 WeakPolarHBondContact O-CB 3.33Å; Q424-R428 PolarHBondContact O-N 2.97Å
425	E	93.1	Very high	92.6	Very high	43 Å²	43	70.2 Å²	70.2	20%	0.201	34%	0.338	C	S	.	.	H	α-helix	trans	-69.9	-41.9	173.6	179	136.1	-154.2	0	0	112.5	F410 S421 K423 R428 D429 K496 I500	F410-E425 HydrophobicContact CE1-CG 4.27Å; F410-E425 HydrophobicContact CZ-CG 4.32Å; S421-E425 PolarHBondContact O-N 3.38Å; K423-E425 VanDerWaalsContact C-N 3.28Å; K423-E425 PolarHBondContact O-N 3.22Å; E425-R428 PolarHBondContact O-N 3.3Å; E425-R428 IonicContact OE1-CZ 2.6Å; E425-R428 IonicContact OE1-NH1 2.68Å; E425-R428 IonicContact OE1-NH2 3.61Å; E425-R428 PolarHBondContact OE1-NH2 2.98Å; E425-D429 WeakPolarHBondContact O-CB 3.39Å; E425-D429 PolarHBondContact O-N 3.06Å; E425-K496 IonicContact OE1-NZ 3.6Å; E425-K496 PolarHBondContact OE1-NZ 3.4Å; E425-I500 HydrophobicContact CG-CD1 4.23Å
426	F	94.1	Very high	92.6	Very high	5 Å²	5	66.4 Å²	66.4	2%	0.022	32%	0.318	C	S	.	.	H	α-helix	trans	-57.4	-50.4	172.6	-179.8	-85.2	0	0	0	111.6	V289 W292 V293 Y422 K423 R428 D429 H430 L497 I500 K501	V289-F426 HydrophobicContact CG1-CE1 4Å; V289-F426 HydrophobicContact CG1-CZ 3.82Å; W292-F426 HydrophobicContact CE3-CE1 4.34Å; W292-F426 AromaticContact CZ3-CD1 3.9Å; W292-F426 HydrophobicContact CZ3-CD1 3.9Å; W292-F426 HydrophobicContact CZ3-CE1 4.1Å; V293-F426 HydrophobicContact CG2-CE1 4.25Å; Y422-F426 WeakPolarHBondContact O-CB 3.37Å; Y422-F426 PolarHBondContact O-N 3.3Å; K423-F426 WeakPolarHBondContact O-CB 3.36Å; K423-F426 PolarHBondContact O-N 2.93Å; F426-R428 VanDerWaalsContact C-N 3.29Å; F426-R428 PolarHBondContact O-N 3.14Å; F426-D429 PolarHBondContact O-N 2.91Å; F426-H430 HydrophobicContact CD1-CB 4.48Å; F426-H430 HydrophobicContact CE1-CB 4.28Å; F426-H430 WeakPolarHBondContact O-CB 3.44Å; F426-H430 PolarHBondContact O-N 2.87Å; F426-L497 HydrophobicContact CB-CD2 4.42Å; F426-L497 HydrophobicContact CD2-CB 4.17Å; F426-L497 HydrophobicContact CD2-CD2 3.51Å; F426-L497 HydrophobicContact CD2-CG 4.47Å; F426-L497 HydrophobicContact CE2-CB 3.83Å; F426-L497 HydrophobicContact CE2-CD2 3.79Å; F426-L497 HydrophobicContact CE2-CG 4.4Å; F426-L497 WeakPolarHBondContact CE2-O 3.39Å; F426-L497 HydrophobicContact CG-CD2 3.95Å; F426-L497 HydrophobicContact CZ-CD2 4.45Å; F426-L497 WeakPolarHBondContact O-CD2 3.45Å; F426-I500 HydrophobicContact CB-CG2 3.95Å; F426-I500 HydrophobicContact CD2-CB 4.41Å; F426-I500 HydrophobicContact CD2-CG2 4.35Å; F426-K501 HydrophobicContact CD2-CB 4.45Å; F426-K501 HydrophobicContact CE2-CB 3.95Å
427	D	92.8	Very high	92.5	Very high	40 Å²	40	63.7 Å²	63.7	21%	0.214	31%	0.305	C	S	.	.	H	α-helix	trans	-61.3	-38.2	-177.9	-69.4	-21.8	0	0	0	111.2	K423 L431	K423-D427 WeakPolarHBondContact CG-OD2 3.42Å; K423-D427 IonicContact NZ-OD1 3.95Å; K423-D427 IonicContact NZ-OD2 2.75Å; K423-D427 PolarHBondContact NZ-OD2 3.35Å; K423-D427 WeakPolarHBondContact O-CB 3.42Å; K423-D427 VanDerWaalsContact O-CG 3.3Å; K423-D427 PolarHBondContact O-N 3.08Å; D427-L431 WeakPolarHBondContact O-CG 3.04Å; D427-L431 PolarHBondContact O-N 3.46Å
428	R	94.9	Very high	92.4	Very high	133 Å²	133	57.9 Å²	57.9	50%	0.502	29%	0.287	S	S	.	.	H	α-helix	trans	-66.4	-52.7	175	-175.2	-164.7	73	-149.7	0.3	112.5	Q424 E425 F426 H430 L431 E432	Q424-R428 WeakPolarHBondContact O-CB 3.33Å; Q424-R428 PolarHBondContact O-N 2.97Å; E425-R428 PolarHBondContact O-N 3.3Å; E425-R428 IonicContact OE1-CZ 2.6Å; E425-R428 IonicContact OE1-NH1 2.68Å; E425-R428 IonicContact OE1-NH2 3.61Å; E425-R428 PolarHBondContact OE1-NH2 2.98Å; F426-R428 VanDerWaalsContact C-N 3.29Å; F426-R428 PolarHBondContact O-N 3.14Å; R428-H430 VanDerWaalsContact C-N 3.28Å; R428-H430 PolarHBondContact O-N 2.97Å; R428-L431 PolarHBondContact O-N 2.99Å; R428-E432 PolarHBondContact O-N 2.87Å
429	D	92.5	Very high	92.4	Very high	3 Å²	3	59.7 Å²	59.7	2%	0.016	30%	0.295	C	S	.	.	H	α-helix	trans	-74	-22.6	-174.5	-75.7	16.2	0	0	0	111.8	E425 F426 Y433 L493 K496 L497	E425-D429 WeakPolarHBondContact O-CB 3.39Å; E425-D429 PolarHBondContact O-N 3.06Å; F426-D429 PolarHBondContact O-N 2.91Å; D429-Y433 WeakPolarHBondContact O-CB 3.36Å; D429-Y433 PolarHBondContact O-N 3.44Å; D429-L493 HydrophobicContact CB-CD2 4Å; D429-K496 WeakPolarHBondContact OD2-CD 3.37Å; D429-K496 VanDerWaalsContact OD2-CE 3.31Å; D429-K496 WeakPolarHBondContact OD2-CE 3.42Å; D429-K496 IonicContact OD2-NZ 3.77Å; D429-K496 PolarHBondContact OD2-NZ 3.26Å; D429-L497 HydrophobicContact CB-CD2 3.91Å
430	H	93	Very high	92.2	Very high	24 Å²	24	58.7 Å²	58.7	11%	0.111	29%	0.292	C	S	.	.	H	α-helix	trans	-71.1	-33.1	172.5	178.9	-137.9	0	0	0	112.7	V289 F426 R428 Y433 K434 L497	V289-H430 VanDerWaalsContact CG1-CE1 3.42Å; V289-H430 WeakPolarHBondContact CG1-CE1 3.49Å; F426-H430 HydrophobicContact CD1-CB 4.48Å; F426-H430 HydrophobicContact CE1-CB 4.28Å; F426-H430 WeakPolarHBondContact O-CB 3.44Å; F426-H430 PolarHBondContact O-N 2.87Å; R428-H430 VanDerWaalsContact C-N 3.28Å; R428-H430 PolarHBondContact O-N 2.97Å; H430-Y433 PolarHBondContact O-N 3.31Å; H430-K434 WeakPolarHBondContact NE2-CE 3.45Å; H430-K434 PolarHBondContact O-N 3.37Å; H430-L497 HydrophobicContact CB-CD1 4.19Å; H430-L497 HydrophobicContact CB-CD2 4.06Å
431	L	94	Very high	91.9	Very high	110 Å²	110	58.7 Å²	58.7	58%	0.576	29%	0.293	S	S	*	.	H	α-helix	trans	-65.5	-48	170.6	-70	167.7	0	0	0	110.9	D427 R428 Y433 K434 D435	D427-L431 WeakPolarHBondContact O-CG 3.04Å; D427-L431 PolarHBondContact O-N 3.46Å; R428-L431 PolarHBondContact O-N 2.99Å; L431-Y433 VanDerWaalsContact C-N 3.27Å; L431-Y433 PolarHBondContact O-N 2.87Å; L431-K434 PolarHBondContact O-N 3.44Å; L431-K434 VanDerWaalsContact O-N 3.15Å; L431-D435 PolarHBondContact O-N 3.22Å
432	E	92.9	Very high	91.8	Very high	66 Å²	66	60.3 Å²	60.3	31%	0.308	30%	0.295	S	S	.	.	H	α-helix	trans	-58.6	-40.7	175.3	-163.9	-162.7	146.4	0	0	111.6	R428 L436 R489 L493	R428-E432 PolarHBondContact O-N 2.87Å; E432-L436 HydrophobicContact CG-CD1 4.04Å; E432-L436 WeakPolarHBondContact O-CB 3.18Å; E432-L436 VanDerWaalsContact O-CG 3.3Å; E432-L436 WeakPolarHBondContact O-CG 3.45Å; E432-L436 PolarHBondContact O-N 3.48Å; E432-R489 WeakPolarHBondContact OE1-CG 3.31Å; E432-R489 IonicContact OE1-CZ 3.71Å; E432-R489 IonicContact OE1-NE 3.48Å; E432-R489 PolarHBondContact OE1-NE 3.5Å; E432-R489 IonicContact OE1-NH2 2.71Å; E432-R489 PolarHBondContact OE1-NH2 3.34Å; E432-R489 IonicContact OE2-CZ 2.69Å; E432-R489 IonicContact OE2-NE 3.56Å; E432-R489 IonicContact OE2-NH2 2.75Å; E432-R489 PolarHBondContact OE2-NH2 3.1Å; E432-L493 HydrophobicContact CB-CD1 4.11Å; E432-L493 HydrophobicContact CG-CD1 4.02Å
433	Y	92.8	Very high	91.5	Very high	35 Å²	35	60.6 Å²	60.6	14%	0.137	30%	0.297	C	S	.	.	H	α-helix	trans	-61.3	-44.4	176.2	176.2	-99.1	0	0	0	112.3	D429 H430 L431 Q437 C490 L493 K494 L497	D429-Y433 WeakPolarHBondContact O-CB 3.36Å; D429-Y433 PolarHBondContact O-N 3.44Å; H430-Y433 PolarHBondContact O-N 3.31Å; L431-Y433 VanDerWaalsContact C-N 3.27Å; L431-Y433 PolarHBondContact O-N 2.87Å; Y433-Q437 VanDerWaalsContact CE1-OE1 3.32Å; Y433-Q437 VanDerWaalsContact O-CB 3.29Å; Y433-Q437 WeakPolarHBondContact O-CB 3.41Å; Y433-Q437 PolarHBondContact O-N 3.42Å; Y433-Q437 PolarHBondContact OH-OE1 3.37Å; Y433-C490 WeakPolarHBondContact CE2-O 3.48Å; Y433-L493 HydrophobicContact CD2-CB 3.99Å; Y433-K494 HydrophobicContact CD2-CB 4.39Å; Y433-K494 HydrophobicContact CE2-CB 3.79Å; Y433-L497 HydrophobicContact CG-CD1 4.05Å
434	K	92.6	Very high	91.1	Very high	77 Å²	77	61.9 Å²	61.9	34%	0.335	31%	0.305	S	S	.	.	H	α-helix	trans	-65.4	-46.1	178.1	-83.3	-177	165.3	-173.2	0	112.7	E290 H430 L431 Q437 A438	E290-K434 IonicContact OE1-NZ 3.18Å; E290-K434 PolarHBondContact OE1-NZ 2.87Å; H430-K434 WeakPolarHBondContact NE2-CE 3.45Å; H430-K434 PolarHBondContact O-N 3.37Å; L431-K434 PolarHBondContact O-N 3.44Å; L431-K434 VanDerWaalsContact O-N 3.15Å; K434-Q437 PolarHBondContact O-N 2.93Å; K434-A438 WeakPolarHBondContact O-CB 3.23Å; K434-A438 PolarHBondContact O-N 2.99Å
435	D	93.3	Very high	90.8	Very high	117 Å²	117	61.6 Å²	61.6	63%	0.626	30%	0.302	S	S	*	.	H	α-helix	trans	-63.6	-44.2	-180	-72.5	-15.4	0	0	0	111.1	L431 A438 E439	L431-D435 PolarHBondContact O-N 3.22Å; D435-A438 PolarHBondContact O-N 2.99Å; D435-E439 PolarHBondContact O-N 3.03Å
436	L	90.6	Very high	90.4	Very high	23 Å²	23	62.8 Å²	62.8	12%	0.12	31%	0.31	C	S	.	.	H	α-helix	trans	-64	-38.8	174.1	-73.9	172	0	0	0	112.5	E432 L440 K486 R489 L493	E432-L436 HydrophobicContact CG-CD1 4.04Å; E432-L436 WeakPolarHBondContact O-CB 3.18Å; E432-L436 VanDerWaalsContact O-CG 3.3Å; E432-L436 WeakPolarHBondContact O-CG 3.45Å; E432-L436 PolarHBondContact O-N 3.48Å; L436-L440 WeakPolarHBondContact O-CD1 3.37Å; L436-L440 WeakPolarHBondContact O-CG 3.5Å; L436-L440 PolarHBondContact O-N 2.88Å; L436-K486 HydrophobicContact CD2-CB 4.13Å; L436-K486 HydrophobicContact CD2-CD 4.34Å; L436-K486 HydrophobicContact CD2-CG 4.08Å; L436-R489 HydrophobicContact CD1-CB 4.1Å; L436-R489 HydrophobicContact CD1-CG 3.58Å; L436-L493 HydrophobicContact CD1-CD1 3.8Å
437	Q	87.4	Confident	89.8	Confident	73 Å²	73	63.6 Å²	63.6	34%	0.341	31%	0.314	S	S	.	.	H	α-helix	trans	-65.7	-45.1	176.3	-178.7	166.3	-6.6	0	0	111	Y433 K434 E439 L440 D441	Y433-Q437 VanDerWaalsContact CE1-OE1 3.32Å; Y433-Q437 VanDerWaalsContact O-CB 3.29Å; Y433-Q437 WeakPolarHBondContact O-CB 3.41Å; Y433-Q437 PolarHBondContact O-N 3.42Å; Y433-Q437 PolarHBondContact OH-OE1 3.37Å; K434-Q437 PolarHBondContact O-N 2.93Å; Q437-E439 PolarHBondContact O-N 3.19Å; Q437-L440 PolarHBondContact O-N 3.35Å; Q437-D441 VanDerWaalsContact CG-OD2 3.27Å; Q437-D441 WeakPolarHBondContact CG-OD2 3.46Å; Q437-D441 PolarHBondContact NE2-OD2 3.46Å; Q437-D441 WeakPolarHBondContact O-CB 3.44Å; Q437-D441 PolarHBondContact O-N 3.24Å
438	A	91.1	Very high	89.3	Confident	50 Å²	50	63.9 Å²	63.9	41%	0.413	32%	0.319	S	S	.	.	H	α-helix	trans	-59.3	-43.6	177.6	0	0	0	0	0	112.5	K434 D435 D441 I442	K434-A438 WeakPolarHBondContact O-CB 3.23Å; K434-A438 PolarHBondContact O-N 2.99Å; D435-A438 PolarHBondContact O-N 2.99Å; A438-D441 PolarHBondContact O-N 3.12Å; A438-I442 WeakPolarHBondContact O-CD1 3.39Å; A438-I442 VanDerWaalsContact O-CG1 3.25Å; A438-I442 WeakPolarHBondContact O-CG1 2.88Å; A438-I442 PolarHBondContact O-N 3.22Å
439	E	89.6	Confident	88.7	Confident	91 Å²	91	60.2 Å²	60.2	43%	0.425	31%	0.309	S	S	.	.	H	α-helix	trans	-61.8	-45.1	176.7	-164.7	-164.9	153.3	0	0	112.1	D435 Q437 L443 K486	D435-E439 PolarHBondContact O-N 3.03Å; Q437-E439 PolarHBondContact O-N 3.19Å; E439-L443 PolarHBondContact O-N 2.97Å; E439-K486 IonicContact OE1-NZ 3.59Å; E439-K486 PolarHBondContact OE1-NZ 3.35Å; E439-K486 WeakPolarHBondContact OE2-CD 3.3Å; E439-K486 IonicContact OE2-NZ 2.71Å; E439-K486 PolarHBondContact OE2-NZ 3.41Å
440	L	88.3	Confident	88.3	Confident	15 Å²	15	61 Å²	61	8%	0.079	31%	0.313	C	S	.	.	H	α-helix	trans	-65.4	-39.5	179	-66.8	169.9	0	0	0	111.6	L436 Q437 L443 N444 Y483 K486 C490	L436-L440 WeakPolarHBondContact O-CD1 3.37Å; L436-L440 WeakPolarHBondContact O-CG 3.5Å; L436-L440 PolarHBondContact O-N 2.88Å; Q437-L440 PolarHBondContact O-N 3.35Å; L440-L443 PolarHBondContact O-N 3.15Å; L440-N444 VanDerWaalsContact O-CG 3.24Å; L440-N444 PolarHBondContact O-N 2.86Å; L440-N444 VanDerWaalsContact O-N 3.11Å; L440-N444 PolarHBondContact O-ND2 2.75Å; L440-Y483 HydrophobicContact CD2-CD2 3.74Å; L440-Y483 HydrophobicContact CD2-CE1 4.17Å; L440-Y483 HydrophobicContact CD2-CE2 3.36Å; L440-Y483 HydrophobicContact CD2-CG 4.3Å; L440-K486 HydrophobicContact CD2-CB 4.37Å; L440-C490 HydrophobicContact CD1-CB 4.02Å
441	D	86.2	Confident	87.5	Confident	73 Å²	73	63.4 Å²	63.4	39%	0.39	33%	0.327	S	S	.	.	H	α-helix	trans	-76.5	-30.8	-177.2	-73.2	-21.4	0	0	0	113	Q437 A438 N444 K445	Q437-D441 VanDerWaalsContact CG-OD2 3.27Å; Q437-D441 WeakPolarHBondContact CG-OD2 3.46Å; Q437-D441 PolarHBondContact NE2-OD2 3.46Å; Q437-D441 WeakPolarHBondContact O-CB 3.44Å; Q437-D441 PolarHBondContact O-N 3.24Å; A438-D441 PolarHBondContact O-N 3.12Å; D441-N444 PolarHBondContact O-N 3.03Å; D441-N444 PolarHBondContact OD1-ND2 2.63Å; D441-K445 WeakPolarHBondContact O-CB 3.31Å; D441-K445 PolarHBondContact O-N 3.49Å
442	I	89.8	Confident	87	Confident	102 Å²	102	66.2 Å²	66.2	52%	0.523	33%	0.33	S	S	.	.	H	α-helix	trans	-58.2	-51	167.6	-71.1	163.1	0	0	0	110.1	A438 N444 K445 D446	A438-I442 WeakPolarHBondContact O-CD1 3.39Å; A438-I442 VanDerWaalsContact O-CG1 3.25Å; A438-I442 WeakPolarHBondContact O-CG1 2.88Å; A438-I442 PolarHBondContact O-N 3.22Å; I442-N444 VanDerWaalsContact C-N 3.27Å; I442-N444 PolarHBondContact O-N 3.43Å; I442-K445 WeakPolarHBondContact O-CB 3.35Å; I442-K445 PolarHBondContact O-N 3Å; I442-K445 VanDerWaalsContact O-N 3.08Å; I442-D446 PolarHBondContact O-N 3.26Å
443	L	86.3	Confident	86.6	Confident	23 Å²	23	67.7 Å²	67.7	12%	0.12	34%	0.337	C	S	.	.	H	α-helix	trans	-63	-34.1	-179.9	-169.3	149.9	0	0	0	112.4	E439 L440 L447 I477 K478 Y483	E439-L443 PolarHBondContact O-N 2.97Å; L440-L443 PolarHBondContact O-N 3.15Å; L443-L447 WeakPolarHBondContact O-CB 3.38Å; L443-L447 PolarHBondContact O-N 3.2Å; L443-I477 HydrophobicContact CD1-CB 4.22Å; L443-I477 HydrophobicContact CD1-CG2 3.59Å; L443-K478 HydrophobicContact CD2-CB 3.93Å; L443-K478 HydrophobicContact CD2-CD 3.95Å; L443-K478 HydrophobicContact CD2-CG 4.08Å; L443-Y483 HydrophobicContact CB-CE2 4.42Å; L443-Y483 HydrophobicContact CD1-CD2 4.07Å; L443-Y483 HydrophobicContact CD1-CE2 4.16Å; L443-Y483 HydrophobicContact CD2-CD2 4.41Å; L443-Y483 HydrophobicContact CD2-CE2 3.85Å; L443-Y483 HydrophobicContact CG-CE2 4.38Å
444	N	83.8	Confident	85.9	Confident	49 Å²	49	66.8 Å²	66.8	26%	0.262	34%	0.335	S	S	.	.	H	α-helix	trans	-66.5	-42.6	173.3	-68.5	-40.3	0	0	0	112.2	L440 D441 I442 L447 S448 K478 Y483	L440-N444 VanDerWaalsContact O-CG 3.24Å; L440-N444 PolarHBondContact O-N 2.86Å; L440-N444 VanDerWaalsContact O-N 3.11Å; L440-N444 PolarHBondContact O-ND2 2.75Å; D441-N444 PolarHBondContact O-N 3.03Å; D441-N444 PolarHBondContact OD1-ND2 2.63Å; I442-N444 VanDerWaalsContact C-N 3.27Å; I442-N444 PolarHBondContact O-N 3.43Å; N444-L447 PolarHBondContact O-N 2.85Å; N444-S448 PolarHBondContact O-N 3.19Å; N444-K478 VanDerWaalsContact OD1-CE 3.31Å; N444-K478 WeakPolarHBondContact OD1-CE 3.41Å; N444-K478 PolarHBondContact OD1-NZ 3.41Å; N444-Y483 PolarHBondContact OD1-OH 2.87Å
445	K	87	Confident	85.2	Confident	141 Å²	141	70.5 Å²	70.5	61%	0.613	36%	0.358	S	S	*	.	H	α-helix	trans	-66	-44.1	179.4	-174.2	178.8	-178	179.3	0	112.1	D441 I442 L447 S448 N449	D441-K445 WeakPolarHBondContact O-CB 3.31Å; D441-K445 PolarHBondContact O-N 3.49Å; I442-K445 WeakPolarHBondContact O-CB 3.35Å; I442-K445 PolarHBondContact O-N 3Å; I442-K445 VanDerWaalsContact O-N 3.08Å; K445-L447 VanDerWaalsContact C-N 3.33Å; K445-L447 PolarHBondContact O-N 3.33Å; K445-S448 PolarHBondContact O-N 3.48Å; K445-N449 PolarHBondContact O-N 3.34Å; K445-N449 PolarHBondContact O-ND2 3.28Å
446	D	84.5	Confident	84.4	Confident	69 Å²	69	68.1 Å²	68.1	37%	0.369	36%	0.361	S	S	.	.	H	α-helix	trans	-65.6	-37.2	178.1	-66.3	-18.6	0	0	0	111.7	I442 N449 L450 L474	I442-D446 PolarHBondContact O-N 3.26Å; D446-N449 PolarHBondContact O-N 3.04Å; D446-L450 WeakPolarHBondContact O-CG 3.36Å; D446-L450 PolarHBondContact O-N 3.28Å; D446-L474 HydrophobicContact CB-CD1 3.72Å
447	L	82.3	Confident	83.9	Confident	22 Å²	22	69.1 Å²	69.1	12%	0.115	37%	0.366	C	S	.	.	H	α-helix	trans	-66.4	-38.8	174.4	-167.3	152.9	0	0	0	112.1	L443 N444 K445 D451 Y471 L474 K478	L443-L447 WeakPolarHBondContact O-CB 3.38Å; L443-L447 PolarHBondContact O-N 3.2Å; N444-L447 PolarHBondContact O-N 2.85Å; K445-L447 VanDerWaalsContact C-N 3.33Å; K445-L447 PolarHBondContact O-N 3.33Å; L447-D451 PolarHBondContact O-N 3.11Å; L447-Y471 HydrophobicContact CD2-CD2 4.44Å; L447-Y471 HydrophobicContact CD2-CE2 3.67Å; L447-Y471 HydrophobicContact CG-CD2 4.19Å; L447-Y471 HydrophobicContact CG-CE2 3.89Å; L447-L474 HydrophobicContact CB-CD1 4.33Å; L447-L474 HydrophobicContact CD1-CB 4.41Å; L447-K478 HydrophobicContact CD1-CD 4.02Å
448	S	82.7	Confident	82.9	Confident	46 Å²	46	73.3 Å²	73.3	32%	0.322	39%	0.386	S	S	.	.	H	α-helix	trans	-66.9	-41.8	173.3	172.7	0	0	0	0	112.2	N444 K445 L450 D451 R452	N444-S448 PolarHBondContact O-N 3.19Å; K445-S448 PolarHBondContact O-N 3.48Å; S448-L450 VanDerWaalsContact C-N 3.32Å; S448-L450 PolarHBondContact O-N 3.18Å; S448-D451 PolarHBondContact O-N 2.96Å; S448-R452 PolarHBondContact O-N 2.8Å
449	N	82.8	Confident	81.8	Confident	55 Å²	55	79.4 Å²	79.4	29%	0.294	41%	0.406	S	S	.	.	H	α-helix	trans	-56.5	-45.5	174.6	-76.9	-40	0	0	0	111.7	K445 D446 R452 E453	K445-N449 PolarHBondContact O-N 3.34Å; K445-N449 PolarHBondContact O-ND2 3.28Å; D446-N449 PolarHBondContact O-N 3.04Å; N449-R452 PolarHBondContact O-N 3.05Å; N449-R452 PolarHBondContact OD1-NH2 2.88Å; N449-R452 VanDerWaalsContact OD1-NH2 3.14Å; N449-E453 PolarHBondContact O-N 3.44Å
450	L	84	Confident	80.6	Confident	19 Å²	19	77.5 Å²	77.5	10%	0.099	41%	0.411	C	S	.	.	H	α-helix	trans	-71.2	-36.2	178.5	-71.6	172.2	0	0	0	113.4	D446 S448 R452 E453 L454 T467 E470 Y471 L474	D446-L450 WeakPolarHBondContact O-CG 3.36Å; D446-L450 PolarHBondContact O-N 3.28Å; S448-L450 VanDerWaalsContact C-N 3.32Å; S448-L450 PolarHBondContact O-N 3.18Å; L450-R452 VanDerWaalsContact C-N 3.32Å; L450-R452 PolarHBondContact O-N 3.33Å; L450-E453 PolarHBondContact O-N 3.3Å; L450-L454 WeakPolarHBondContact O-CB 3.11Å; L450-L454 VanDerWaalsContact O-CG 3.31Å; L450-L454 WeakPolarHBondContact O-CG 3.49Å; L450-L454 PolarHBondContact O-N 3.26Å; L450-T467 HydrophobicContact CD2-CG2 4.45Å; L450-E470 HydrophobicContact CD1-CB 4.02Å; L450-Y471 HydrophobicContact CB-CD2 4.07Å; L450-L474 HydrophobicContact CD1-CD1 3.82Å; L450-L474 HydrophobicContact CD1-CG 4.41Å
451	D	76.6	Confident	80.2	Confident	75 Å²	75	78 Å²	78	40%	0.401	42%	0.415	S	S	.	.	H	α-helix	trans	-59.3	-45.3	172.9	-129.2	33.2	0	0	0	109.8	L447 S448 L454 D455 Y471	L447-D451 PolarHBondContact O-N 3.11Å; S448-D451 PolarHBondContact O-N 2.96Å; D451-L454 PolarHBondContact O-N 3.21Å; D451-D455 PolarHBondContact O-N 2.95Å; D451-D455 VanDerWaalsContact O-N 3.08Å; D451-Y471 HydrophobicContact CB-CE2 4.05Å; D451-Y471 WeakPolarHBondContact OD1-CE2 3.42Å; D451-Y471 PolarHBondContact OD1-OH 2.9Å
452	R	83.1	Confident	80	Confident	169 Å²	169	79 Å²	79	64%	0.638	43%	0.426	S	S	*	.	H	α-helix	trans	-68	-32.6	177.1	-173.3	-173.8	64.2	-165.9	-10.6	113.4	S448 N449 L450 G456	S448-R452 PolarHBondContact O-N 2.8Å; N449-R452 PolarHBondContact O-N 3.05Å; N449-R452 PolarHBondContact OD1-NH2 2.88Å; N449-R452 VanDerWaalsContact OD1-NH2 3.14Å; L450-R452 VanDerWaalsContact C-N 3.32Å; L450-R452 PolarHBondContact O-N 3.33Å; R452-G456 PolarHBondContact O-N 3.23Å
453	E	84.4	Confident	79.5	Confident	98 Å²	98	80.2 Å²	80.2	46%	0.458	43%	0.429	S	S	.	.	H	α-helix	trans	-71.5	-40.3	175.3	-170.8	169.2	176.4	0	0	111.3	N449 L450 D455 G456 L457 T467	N449-E453 PolarHBondContact O-N 3.44Å; L450-E453 PolarHBondContact O-N 3.3Å; E453-D455 PolarHBondContact O-N 2.96Å; E453-G456 PolarHBondContact O-N 2.96Å; E453-L457 HydrophobicContact CG-CD1 4Å; E453-L457 WeakPolarHBondContact O-CG 3.29Å; E453-L457 PolarHBondContact O-N 3Å; E453-T467 HydrophobicContact CG-CG2 4.13Å
454	L	78.2	Confident	79.3	Confident	16 Å²	16	81 Å²	81	8%	0.084	43%	0.432	C	S	.	.	H	α-helix	trans	-60.9	-41.5	173.5	-76.1	165.5	0	0	0	112.7	L450 D451 G456 L457 F464 T467 L468 Y471	L450-L454 WeakPolarHBondContact O-CB 3.11Å; L450-L454 VanDerWaalsContact O-CG 3.31Å; L450-L454 WeakPolarHBondContact O-CG 3.49Å; L450-L454 PolarHBondContact O-N 3.26Å; D451-L454 PolarHBondContact O-N 3.21Å; L454-G456 PolarHBondContact O-N 3.47Å; L454-L457 PolarHBondContact O-N 3.33Å; L454-F464 HydrophobicContact CB-CE2 4.46Å; L454-F464 HydrophobicContact CD2-CD2 3.83Å; L454-F464 HydrophobicContact CD2-CE2 3.85Å; L454-F464 HydrophobicContact CD2-CG 4.25Å; L454-F464 HydrophobicContact CD2-CZ 4.28Å; L454-T467 WeakPolarHBondContact CD2-OG1 3.42Å; L454-L468 HydrophobicContact CD1-CD1 4.2Å; L454-L468 HydrophobicContact CD2-CB 3.89Å; L454-L468 HydrophobicContact CD2-CD1 4.46Å; L454-Y471 HydrophobicContact CD1-CD1 4.42Å; L454-Y471 HydrophobicContact CD1-CD2 4.25Å; L454-Y471 HydrophobicContact CD1-CG 3.98Å
455	D	77.3	Confident	78.9	Confident	154 Å²	154	83.4 Å²	83.4	82%	0.824	44%	0.444	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.7	-20.5	173.7	-91.3	-3.4	0	0	0	113.3	D451 E453	D451-D455 PolarHBondContact O-N 2.95Å; D451-D455 VanDerWaalsContact O-N 3.08Å; E453-D455 PolarHBondContact O-N 2.96Å
456	G	76	Confident	78.9	Confident	67 Å²	67	81.9 Å²	81.9	69%	0.691	44%	0.443	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.1	-10.4	179.8	0	0	0	0	0	115.5	R452 E453 L454	R452-G456 PolarHBondContact O-N 3.23Å; E453-G456 PolarHBondContact O-N 2.96Å; L454-G456 PolarHBondContact O-N 3.47Å
457	L	81	Confident	78.7	Confident	44 Å²	44	79.2 Å²	79.2	23%	0.23	43%	0.429	C	S	.	.	S	Bend	trans	-105.3	152.4	-173.2	-71.9	169.8	0	0	0	112.5	E453 L454 E459 Q463 F464 T467	E453-L457 HydrophobicContact CG-CD1 4Å; E453-L457 WeakPolarHBondContact O-CG 3.29Å; E453-L457 PolarHBondContact O-N 3Å; L454-L457 PolarHBondContact O-N 3.33Å; L457-E459 PolarHBondContact O-N 3.46Å; L457-Q463 HydrophobicContact CD1-CB 4.11Å; L457-Q463 HydrophobicContact CD2-CB 4.11Å; L457-F464 HydrophobicContact CB-CB 4.11Å; L457-F464 HydrophobicContact CB-CD2 4.11Å; L457-T467 HydrophobicContact CD1-CG2 4.14Å
458	E	67.1	Low	78.5	Confident	162 Å²	162	81 Å²	81	76%	0.757	44%	0.439	S	S	*	.			trans	-71	127.4	177.2	-172.8	176.9	-171.4	0	0	111	G460 S461 F464	E458-G460 PolarHBondContact O-N 2.95Å; E458-S461 VanDerWaalsContact O-CB 3.27Å; E458-S461 WeakPolarHBondContact O-CB 3.28Å; E458-S461 PolarHBondContact O-N 3.12Å; E458-S461 PolarHBondContact O-OG 2.95Å; E458-F464 WeakPolarHBondContact O-CB 3.3Å
459	E	67.2	Low	78.7	Confident	177 Å²	177	83.4 Å²	83.4	83%	0.827	45%	0.448	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.3	111.2	-178.6	-75.8	-169.3	-168	0	0	112.1	L457 F464	L457-E459 PolarHBondContact O-N 3.46Å; E459-F464 HydrophobicContact CG-CZ 4.49Å
460	G	64.9	Low	79.1	Confident	52 Å²	52	85.7 Å²	85.7	54%	0.536	46%	0.457	S	S	.	.	T	Hydrogen-bonded Turn	trans	85.5	9.3	178.2	0	0	0	0	0	115.6	E458	E458-G460 PolarHBondContact O-N 2.95Å
461	S	79.4	Confident	79	Confident	24 Å²	24	86.1 Å²	86.1	17%	0.168	46%	0.457	C	S	.	.			trans	-59	155.8	156.4	64.4	0	0	0	0	110.9	E458 Q463 F464 L465	E458-S461 VanDerWaalsContact O-CB 3.27Å; E458-S461 WeakPolarHBondContact O-CB 3.28Å; E458-S461 PolarHBondContact O-N 3.12Å; E458-S461 PolarHBondContact O-OG 2.95Å; S461-Q463 VanDerWaalsContact C-N 3.31Å; S461-Q463 PolarHBondContact O-N 2.67Å; S461-F464 WeakPolarHBondContact O-CB 3.3Å; S461-F464 PolarHBondContact O-N 2.95Å; S461-F464 VanDerWaalsContact OG-CB 3.23Å; S461-F464 WeakPolarHBondContact OG-CB 3.46Å; S461-F464 PolarHBondContact OG-N 3.42Å; S461-L465 PolarHBondContact O-N 3.04Å
462	P	82.8	Confident	79.2	Confident	95 Å²	95	85.4 Å²	85.4	62%	0.617	45%	0.453	S	S	*	.	H	α-helix	trans	-60.1	-42	179.1	22.9	-32.9	0	0	0	112	F464 L465 D466	P462-F464 VanDerWaalsContact C-N 3.31Å; P462-F464 PolarHBondContact O-N 3.29Å; P462-L465 WeakPolarHBondContact O-CB 3.12Å; P462-L465 PolarHBondContact O-N 3.1Å; P462-D466 PolarHBondContact O-N 2.93Å
463	Q	79.1	Confident	79.6	Confident	127 Å²	127	82.8 Å²	82.8	59%	0.593	45%	0.447	S	S	*	.	H	α-helix	trans	-60.7	-37.8	177	-69.5	171.1	-40.9	0	0	112.5	L457 S461 L465 D466 T467	L457-Q463 HydrophobicContact CD1-CB 4.11Å; L457-Q463 HydrophobicContact CD2-CB 4.11Å; S461-Q463 VanDerWaalsContact C-N 3.31Å; S461-Q463 PolarHBondContact O-N 2.67Å; Q463-L465 VanDerWaalsContact C-N 3.32Å; Q463-L465 PolarHBondContact O-N 3.47Å; Q463-D466 PolarHBondContact O-N 3.38Å; Q463-T467 WeakPolarHBondContact O-CB 3.41Å; Q463-T467 WeakPolarHBondContact O-CG2 3.31Å; Q463-T467 PolarHBondContact O-N 3.42Å; Q463-T467 PolarHBondContact O-OG1 3.1Å
464	F	80.3	Confident	79.6	Confident	41 Å²	41	79.6 Å²	79.6	18%	0.18	43%	0.432	C	S	.	.	H	α-helix	trans	-65.7	-32.9	173.5	-179.8	-85.3	0	0	0	112.4	L454 L457 E458 E459 S461 P462 T467 L468	L454-F464 HydrophobicContact CB-CE2 4.46Å; L454-F464 HydrophobicContact CD2-CD2 3.83Å; L454-F464 HydrophobicContact CD2-CE2 3.85Å; L454-F464 HydrophobicContact CD2-CG 4.25Å; L454-F464 HydrophobicContact CD2-CZ 4.28Å; L457-F464 HydrophobicContact CB-CB 4.11Å; L457-F464 HydrophobicContact CB-CD2 4.11Å; E458-F464 WeakPolarHBondContact O-CB 3.3Å; E459-F464 HydrophobicContact CG-CZ 4.49Å; S461-F464 WeakPolarHBondContact O-CB 3.3Å; S461-F464 PolarHBondContact O-N 2.95Å; S461-F464 VanDerWaalsContact OG-CB 3.23Å; S461-F464 WeakPolarHBondContact OG-CB 3.46Å; S461-F464 PolarHBondContact OG-N 3.42Å; P462-F464 VanDerWaalsContact C-N 3.31Å; P462-F464 PolarHBondContact O-N 3.29Å; F464-T467 WeakPolarHBondContact CA-OG1 3.32Å; F464-T467 PolarHBondContact O-OG1 2.82Å; F464-L468 HydrophobicContact CE1-CD2 4.13Å; F464-L468 WeakPolarHBondContact O-CB 3.41Å; F464-L468 PolarHBondContact O-N 3.38Å
465	L	76.8	Confident	79.8	Confident	99 Å²	99	83.1 Å²	83.1	52%	0.518	45%	0.447	S	S	.	.	H	α-helix	trans	-75	-39.6	177.4	-65.5	175	0	0	0	112.1	S461 P462 Q463 L468 D469	S461-L465 PolarHBondContact O-N 3.04Å; P462-L465 WeakPolarHBondContact O-CB 3.12Å; P462-L465 PolarHBondContact O-N 3.1Å; Q463-L465 VanDerWaalsContact C-N 3.32Å; Q463-L465 PolarHBondContact O-N 3.47Å; L465-L468 PolarHBondContact O-N 3.13Å; L465-D469 PolarHBondContact O-N 3.45Å; L465-D469 VanDerWaalsContact O-N 3.15Å
466	D	86.9	Confident	80.1	Confident	109 Å²	109	83.9 Å²	83.9	58%	0.583	44%	0.439	S	S	*	.	H	α-helix	trans	-67.3	-50.9	179.2	-63.5	-26.1	0	0	0	111	P462 Q463 L468 D469 E470	P462-D466 PolarHBondContact O-N 2.93Å; Q463-D466 PolarHBondContact O-N 3.38Å; D466-L468 PolarHBondContact O-N 3.42Å; D466-D469 PolarHBondContact O-N 3.07Å; D466-D469 VanDerWaalsContact O-N 3.11Å; D466-E470 PolarHBondContact O-N 2.85Å; D466-E470 VanDerWaalsContact O-N 3.15Å
467	T	79.5	Confident	80.6	Confident	13 Å²	13	84.3 Å²	84.3	8%	0.08	42%	0.424	C	S	.	.	H	α-helix	trans	-59.8	-33.6	174.8	49.9	0	0	0	0	112.5	L450 E453 L454 L457 Q463 F464 E470 Y471	L450-T467 HydrophobicContact CD2-CG2 4.45Å; E453-T467 HydrophobicContact CG-CG2 4.13Å; L454-T467 WeakPolarHBondContact CD2-OG1 3.42Å; L457-T467 HydrophobicContact CD1-CG2 4.14Å; Q463-T467 WeakPolarHBondContact O-CB 3.41Å; Q463-T467 WeakPolarHBondContact O-CG2 3.31Å; Q463-T467 PolarHBondContact O-N 3.42Å; Q463-T467 PolarHBondContact O-OG1 3.1Å; F464-T467 WeakPolarHBondContact CA-OG1 3.32Å; F464-T467 PolarHBondContact O-OG1 2.82Å; T467-E470 PolarHBondContact O-N 2.85Å; T467-Y471 WeakPolarHBondContact O-CB 3.4Å; T467-Y471 PolarHBondContact O-N 3.27Å
468	L	78.7	Confident	80.7	Confident	60 Å²	60	85.4 Å²	85.4	31%	0.314	43%	0.427	S	S	.	.	H	α-helix	trans	-69	-34.4	176.2	-177.7	61.8	0	0	0	112.5	L454 F464 L465 D466 N472	L454-L468 HydrophobicContact CD1-CD1 4.2Å; L454-L468 HydrophobicContact CD2-CB 3.89Å; L454-L468 HydrophobicContact CD2-CD1 4.46Å; F464-L468 HydrophobicContact CE1-CD2 4.13Å; F464-L468 WeakPolarHBondContact O-CB 3.41Å; F464-L468 PolarHBondContact O-N 3.38Å; L465-L468 PolarHBondContact O-N 3.13Å; D466-L468 PolarHBondContact O-N 3.42Å; L468-N472 WeakPolarHBondContact O-CB 3.48Å; L468-N472 PolarHBondContact O-N 2.99Å; L468-N472 PolarHBondContact O-ND2 3.49Å
469	D	87.4	Confident	81.4	Confident	96 Å²	96	85.9 Å²	85.9	51%	0.513	43%	0.426	S	S	.	.	H	α-helix	trans	-70.8	-42	173.4	-166.3	65.1	0	0	0	111.3	L465 D466 Y471 N472 K473	L465-D469 PolarHBondContact O-N 3.45Å; L465-D469 VanDerWaalsContact O-N 3.15Å; D466-D469 PolarHBondContact O-N 3.07Å; D466-D469 VanDerWaalsContact O-N 3.11Å; D469-Y471 PolarHBondContact O-N 2.96Å; D469-N472 CarbonylContact O-C 3.57Å; D469-N472 PolarHBondContact O-N 3.12Å; D469-N472 VanDerWaalsContact O-N 3.13Å; D469-K473 WeakPolarHBondContact O-CB 3.14Å; D469-K473 PolarHBondContact O-N 3.18Å
470	E	89.6	Confident	82.4	Confident	103 Å²	103	79.3 Å²	79.3	48%	0.481	40%	0.4	S	S	.	.	H	α-helix	trans	-60.8	-43.2	175.6	-62.8	-144.3	130.4	0	0	112.3	L450 D466 T467 N472 K473 L474	L450-E470 HydrophobicContact CD1-CB 4.02Å; D466-E470 PolarHBondContact O-N 2.85Å; D466-E470 VanDerWaalsContact O-N 3.15Å; T467-E470 PolarHBondContact O-N 2.85Å; E470-N472 PolarHBondContact O-N 2.87Å; E470-K473 WeakPolarHBondContact O-CB 3.47Å; E470-K473 PolarHBondContact O-N 3.49Å; E470-L474 PolarHBondContact O-N 3.39Å
471	Y	83.3	Confident	83.5	Confident	27 Å²	27	80.7 Å²	80.7	11%	0.106	41%	0.407	C	S	.	.	H	α-helix	trans	-59.9	-45.4	173	177	-92.8	0	0	0	111.6	L447 L450 D451 L454 T467 D469 K473 L474 K475	L447-Y471 HydrophobicContact CD2-CD2 4.44Å; L447-Y471 HydrophobicContact CD2-CE2 3.67Å; L447-Y471 HydrophobicContact CG-CD2 4.19Å; L447-Y471 HydrophobicContact CG-CE2 3.89Å; L450-Y471 HydrophobicContact CB-CD2 4.07Å; D451-Y471 HydrophobicContact CB-CE2 4.05Å; D451-Y471 WeakPolarHBondContact OD1-CE2 3.42Å; D451-Y471 PolarHBondContact OD1-OH 2.9Å; L454-Y471 HydrophobicContact CD1-CD1 4.42Å; L454-Y471 HydrophobicContact CD1-CD2 4.25Å; L454-Y471 HydrophobicContact CD1-CG 3.98Å; T467-Y471 WeakPolarHBondContact O-CB 3.4Å; T467-Y471 PolarHBondContact O-N 3.27Å; D469-Y471 PolarHBondContact O-N 2.96Å; Y471-K473 VanDerWaalsContact C-N 3.31Å; Y471-K473 PolarHBondContact O-N 2.93Å; Y471-L474 PolarHBondContact O-N 3.05Å; Y471-K475 HydrophobicContact CD1-CD 4.3Å; Y471-K475 HydrophobicContact CE1-CD 3.66Å; Y471-K475 VanDerWaalsContact CE1-NZ 3.33Å; Y471-K475 VanDerWaalsContact O-CB 3.24Å; Y471-K475 WeakPolarHBondContact O-CB 3.47Å; Y471-K475 PolarHBondContact O-N 3.19Å; Y471-K475 PolarHBondContact OH-NZ 3.37Å
472	N	80.3	Confident	84	Confident	60 Å²	60	84 Å²	84	32%	0.321	42%	0.422	S	S	.	.	H	α-helix	trans	-66	-32.1	176.5	-82.7	-68.6	0	0	0	112.7	L468 D469 E470 K475 R476	L468-N472 WeakPolarHBondContact O-CB 3.48Å; L468-N472 PolarHBondContact O-N 2.99Å; L468-N472 PolarHBondContact O-ND2 3.49Å; D469-N472 CarbonylContact O-C 3.57Å; D469-N472 PolarHBondContact O-N 3.12Å; D469-N472 VanDerWaalsContact O-N 3.13Å; E470-N472 PolarHBondContact O-N 2.87Å; N472-K475 PolarHBondContact O-N 2.98Å; N472-R476 VanDerWaalsContact O-CG 3.3Å; N472-R476 WeakPolarHBondContact O-CG 3.45Å; N472-R476 PolarHBondContact O-N 3.1Å
473	K	90.9	Very high	84.2	Confident	114 Å²	114	80.3 Å²	80.3	50%	0.496	40%	0.396	S	S	.	.	H	α-helix	trans	-65.8	-49.9	173.8	174.9	-172.6	173	-167.2	0	111.1	D469 E470 Y471 K475 R476 I477	D469-K473 WeakPolarHBondContact O-CB 3.14Å; D469-K473 PolarHBondContact O-N 3.18Å; E470-K473 WeakPolarHBondContact O-CB 3.47Å; E470-K473 PolarHBondContact O-N 3.49Å; Y471-K473 VanDerWaalsContact C-N 3.31Å; Y471-K473 PolarHBondContact O-N 2.93Å; K473-K475 VanDerWaalsContact C-N 3.28Å; K473-K475 PolarHBondContact O-N 3.47Å; K473-R476 WeakPolarHBondContact O-CB 3.11Å; K473-R476 PolarHBondContact O-N 3.44Å; K473-R476 VanDerWaalsContact O-N 3.12Å; K473-I477 WeakPolarHBondContact O-CG1 3.43Å; K473-I477 PolarHBondContact O-N 3.33Å
474	L	85.4	Confident	84.5	Confident	31 Å²	31	77.7 Å²	77.7	16%	0.162	38%	0.384	C	S	.	.	H	α-helix	trans	-59.7	-39.9	172.2	-64.9	-169.3	0	0	0	111.7	D446 L447 L450 E470 Y471 R476 I477 K478	D446-L474 HydrophobicContact CB-CD1 3.72Å; L447-L474 HydrophobicContact CB-CD1 4.33Å; L447-L474 HydrophobicContact CD1-CB 4.41Å; L450-L474 HydrophobicContact CD1-CD1 3.82Å; L450-L474 HydrophobicContact CD1-CG 4.41Å; E470-L474 PolarHBondContact O-N 3.39Å; Y471-L474 PolarHBondContact O-N 3.05Å; L474-R476 VanDerWaalsContact C-N 3.28Å; L474-R476 PolarHBondContact O-N 3.36Å; L474-I477 HydrophobicContact CD2-CD1 4.3Å; L474-I477 PolarHBondContact O-N 3.42Å; L474-I477 VanDerWaalsContact O-N 3.13Å; L474-K478 WeakPolarHBondContact O-CB 3.05Å; L474-K478 PolarHBondContact O-N 3.11Å
475	K	81.8	Confident	84.9	Confident	90 Å²	90	79.3 Å²	79.3	39%	0.391	40%	0.397	S	S	.	.	H	α-helix	trans	-65.8	-26.4	177.2	-157	163.1	-162.3	154.6	0	113.3	Y471 N472 K473 K479	Y471-K475 HydrophobicContact CD1-CD 4.3Å; Y471-K475 HydrophobicContact CE1-CD 3.66Å; Y471-K475 VanDerWaalsContact CE1-NZ 3.33Å; Y471-K475 VanDerWaalsContact O-CB 3.24Å; Y471-K475 WeakPolarHBondContact O-CB 3.47Å; Y471-K475 PolarHBondContact O-N 3.19Å; Y471-K475 PolarHBondContact OH-NZ 3.37Å; N472-K475 PolarHBondContact O-N 2.98Å; K473-K475 VanDerWaalsContact C-N 3.28Å; K473-K475 PolarHBondContact O-N 3.47Å; K475-K479 WeakPolarHBondContact O-CG 3.25Å
476	R	83.9	Confident	85.5	Confident	171 Å²	171	76.7 Å²	76.7	65%	0.645	38%	0.382	S	S	*	.	H	α-helix	trans	-75.3	-43.3	168.2	-71.8	170.8	-165.2	175.2	11	111.5	N472 K473 L474 K478 K479 S480	N472-R476 VanDerWaalsContact O-CG 3.3Å; N472-R476 WeakPolarHBondContact O-CG 3.45Å; N472-R476 PolarHBondContact O-N 3.1Å; K473-R476 WeakPolarHBondContact O-CB 3.11Å; K473-R476 PolarHBondContact O-N 3.44Å; K473-R476 VanDerWaalsContact O-N 3.12Å; L474-R476 VanDerWaalsContact C-N 3.28Å; L474-R476 PolarHBondContact O-N 3.36Å; R476-K478 VanDerWaalsContact C-N 3.34Å; R476-K478 PolarHBondContact O-N 3.39Å; R476-K479 CarbonylContact O-C 3.18Å; R476-K479 WeakPolarHBondContact O-CA 3.3Å; R476-K479 WeakPolarHBondContact O-CB 3.06Å; R476-K479 PolarHBondContact O-N 2.94Å; R476-S480 PolarHBondContact O-N 3.25Å; R476-S480 VanDerWaalsContact O-N 3.07Å
477	I	86.3	Confident	85.5	Confident	75 Å²	75	76 Å²	76	39%	0.385	37%	0.374	S	S	.	.	H	α-helix	trans	-61.3	-43.3	176.8	-62.1	166.9	0	0	0	110.6	L443 K473 L474 K479 S480 Y483	L443-I477 HydrophobicContact CD1-CB 4.22Å; L443-I477 HydrophobicContact CD1-CG2 3.59Å; K473-I477 WeakPolarHBondContact O-CG1 3.43Å; K473-I477 PolarHBondContact O-N 3.33Å; L474-I477 HydrophobicContact CD2-CD1 4.3Å; L474-I477 PolarHBondContact O-N 3.42Å; L474-I477 VanDerWaalsContact O-N 3.13Å; I477-K479 PolarHBondContact O-N 2.04Å; I477-K479 VanDerWaalsContact O-N 3.13Å; I477-S480 WeakPolarHBondContact O-CB 3.48Å; I477-S480 PolarHBondContact O-N 3.27Å; I477-S480 PolarHBondContact O-OG 3.43Å; I477-Y483 WeakPolarHBondContact O-CB 3.43Å
478	K	83.3	Confident	85.9	Confident	67 Å²	67	80.4 Å²	80.4	29%	0.291	39%	0.389	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.3	-19.3	173.9	-161.2	164.6	-175.2	166	0	114	L443 N444 L447 L474 R476 Y483 Q484	L443-K478 HydrophobicContact CD2-CB 3.93Å; L443-K478 HydrophobicContact CD2-CD 3.95Å; L443-K478 HydrophobicContact CD2-CG 4.08Å; N444-K478 VanDerWaalsContact OD1-CE 3.31Å; N444-K478 WeakPolarHBondContact OD1-CE 3.41Å; N444-K478 PolarHBondContact OD1-NZ 3.41Å; L447-K478 HydrophobicContact CD1-CD 4.02Å; L474-K478 WeakPolarHBondContact O-CB 3.05Å; L474-K478 PolarHBondContact O-N 3.11Å; R476-K478 VanDerWaalsContact C-N 3.34Å; R476-K478 PolarHBondContact O-N 3.39Å; K478-Y483 HydrophobicContact CG-CD1 4.23Å; K478-Y483 HydrophobicContact CG-CE1 3.8Å; K478-Y483 HydrophobicContact CG-CE2 4.28Å; K478-Y483 WeakPolarHBondContact O-CD1 3.43Å; K478-Q484 PolarHBondContact O-NE2 3.09Å
479	K	81	Confident	86.3	Confident	172 Å²	172	81.9 Å²	81.9	75%	0.748	39%	0.39	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.5	-6	172.9	-75.2	-175.6	174.2	-167.1	0	113.8	K475 R476 I477	K475-K479 WeakPolarHBondContact O-CG 3.25Å; R476-K479 CarbonylContact O-C 3.18Å; R476-K479 WeakPolarHBondContact O-CA 3.3Å; R476-K479 WeakPolarHBondContact O-CB 3.06Å; R476-K479 PolarHBondContact O-N 2.94Å; I477-K479 PolarHBondContact O-N 2.04Å; I477-K479 VanDerWaalsContact O-N 3.13Å
480	S	88.8	Confident	86.4	Confident	40 Å²	40	78.2 Å²	78.2	28%	0.28	37%	0.372	S	S	.	.	S	Bend	trans	-65.8	153.1	179.5	72.1	0	0	0	0	111.7	R476 I477 D482 Y483 Q484	R476-S480 PolarHBondContact O-N 3.25Å; R476-S480 VanDerWaalsContact O-N 3.07Å; I477-S480 WeakPolarHBondContact O-CB 3.48Å; I477-S480 PolarHBondContact O-N 3.27Å; I477-S480 PolarHBondContact O-OG 3.43Å; S480-D482 VanDerWaalsContact C-N 3.26Å; S480-D482 PolarHBondContact O-N 2.96Å; S480-Y483 PolarHBondContact O-N 2.77Å; S480-Y483 PolarHBondContact OG-N 3.41Å; S480-Q484 WeakPolarHBondContact O-CG 3.28Å; S480-Q484 PolarHBondContact O-N 3.28Å
481	A	88.1	Confident	86.3	Confident	81 Å²	81	78.5 Å²	78.5	67%	0.669	37%	0.371	S	S	*	.	H	α-helix	trans	-59.1	-39.1	175.8	0	0	0	0	0	111.9	Q484 V485	A481-Q484 PolarHBondContact O-N 2.89Å; A481-V485 WeakPolarHBondContact O-CG2 3.4Å; A481-V485 PolarHBondContact O-N 3.37Å
482	D	88.8	Confident	86.6	Confident	92 Å²	92	80.1 Å²	80.1	49%	0.492	38%	0.378	S	S	.	.	H	α-helix	trans	-58.9	-52.1	178.1	-178.6	57.6	0	0	0	112.1	S480 Q484 V485 K486	S480-D482 VanDerWaalsContact C-N 3.26Å; S480-D482 PolarHBondContact O-N 2.96Å; D482-Q484 VanDerWaalsContact C-N 3.26Å; D482-Q484 PolarHBondContact O-N 3.27Å; D482-V485 PolarHBondContact O-N 2.91Å; D482-K486 WeakPolarHBondContact O-CG 2.97Å; D482-K486 PolarHBondContact O-N 3.5Å; D482-K486 WeakPolarHBondContact OD1-CE 3.33Å; D482-K486 VanDerWaalsContact OD2-CE 3.24Å; D482-K486 WeakPolarHBondContact OD2-CE 3.36Å; D482-K486 IonicContact OD2-NZ 3.37Å
483	Y	88.3	Confident	87	Confident	18 Å²	18	77.3 Å²	77.3	7%	0.071	36%	0.363	C	S	.	.	H	α-helix	trans	-57.8	-38.7	176.1	-176.1	-81.9	0	0	0	112.1	L440 L443 N444 I477 K478 S480 K487	L440-Y483 HydrophobicContact CD2-CD2 3.74Å; L440-Y483 HydrophobicContact CD2-CE1 4.17Å; L440-Y483 HydrophobicContact CD2-CE2 3.36Å; L440-Y483 HydrophobicContact CD2-CG 4.3Å; L443-Y483 HydrophobicContact CB-CE2 4.42Å; L443-Y483 HydrophobicContact CD1-CD2 4.07Å; L443-Y483 HydrophobicContact CD1-CE2 4.16Å; L443-Y483 HydrophobicContact CD2-CD2 4.41Å; L443-Y483 HydrophobicContact CD2-CE2 3.85Å; L443-Y483 HydrophobicContact CG-CE2 4.38Å; N444-Y483 PolarHBondContact OD1-OH 2.87Å; I477-Y483 WeakPolarHBondContact O-CB 3.43Å; K478-Y483 HydrophobicContact CG-CD1 4.23Å; K478-Y483 HydrophobicContact CG-CE1 3.8Å; K478-Y483 HydrophobicContact CG-CE2 4.28Å; K478-Y483 WeakPolarHBondContact O-CD1 3.43Å; S480-Y483 PolarHBondContact O-N 2.77Å; S480-Y483 PolarHBondContact OG-N 3.41Å; Y483-K487 HydrophobicContact CE1-CD 4.24Å; Y483-K487 WeakPolarHBondContact O-CB 3.46Å; Y483-K487 PolarHBondContact O-N 2.89Å
484	Q	85.4	Confident	86.9	Confident	72 Å²	72	75.2 Å²	75.2	34%	0.336	35%	0.354	S	S	.	.	H	α-helix	trans	-72.3	-31.9	176.6	-59.7	-55.7	-36.5	0	0	112.8	K478 S480 A481 D482 R488	K478-Q484 PolarHBondContact O-NE2 3.09Å; S480-Q484 WeakPolarHBondContact O-CG 3.28Å; S480-Q484 PolarHBondContact O-N 3.28Å; A481-Q484 PolarHBondContact O-N 2.89Å; D482-Q484 VanDerWaalsContact C-N 3.26Å; D482-Q484 PolarHBondContact O-N 3.27Å; Q484-R488 WeakPolarHBondContact O-CG 3.47Å; Q484-R488 PolarHBondContact O-N 2.96Å
485	V	88.6	Confident	87	Confident	75 Å²	75	79.4 Å²	79.4	46%	0.455	37%	0.372	S	S	.	.	H	α-helix	trans	-66.1	-50.8	171.8	168.3	0	0	0	0	110.4	A481 D482 K487 R488 R489	A481-V485 WeakPolarHBondContact O-CG2 3.4Å; A481-V485 PolarHBondContact O-N 3.37Å; D482-V485 PolarHBondContact O-N 2.91Å; V485-K487 VanDerWaalsContact C-N 3.31Å; V485-K487 PolarHBondContact O-N 3.49Å; V485-R488 PolarHBondContact O-N 2.98Å; V485-R489 PolarHBondContact O-N 3.34Å
486	K	89.2	Confident	87.4	Confident	45 Å²	45	75.5 Å²	75.5	20%	0.196	36%	0.355	C	S	.	.	H	α-helix	trans	-56.9	-43.5	175.8	-67.1	-175.6	-176.5	-169.3	0	112	L436 E439 L440 D482 R488 R489 C490	L436-K486 HydrophobicContact CD2-CB 4.13Å; L436-K486 HydrophobicContact CD2-CD 4.34Å; L436-K486 HydrophobicContact CD2-CG 4.08Å; E439-K486 IonicContact OE1-NZ 3.59Å; E439-K486 PolarHBondContact OE1-NZ 3.35Å; E439-K486 WeakPolarHBondContact OE2-CD 3.3Å; E439-K486 IonicContact OE2-NZ 2.71Å; E439-K486 PolarHBondContact OE2-NZ 3.41Å; L440-K486 HydrophobicContact CD2-CB 4.37Å; D482-K486 WeakPolarHBondContact O-CG 2.97Å; D482-K486 PolarHBondContact O-N 3.5Å; D482-K486 WeakPolarHBondContact OD1-CE 3.33Å; D482-K486 VanDerWaalsContact OD2-CE 3.24Å; D482-K486 WeakPolarHBondContact OD2-CE 3.36Å; D482-K486 IonicContact OD2-NZ 3.37Å; K486-R488 VanDerWaalsContact C-N 3.35Å; K486-R488 PolarHBondContact O-N 2.91Å; K486-R489 PolarHBondContact O-N 2.87Å; K486-C490 WeakPolarHBondContact O-CB 3.5Å; K486-C490 PolarHBondContact O-N 3.06Å
487	K	87.3	Confident	87.8	Confident	95 Å²	95	67.8 Å²	67.8	41%	0.413	33%	0.326	S	S	.	.	H	α-helix	trans	-62.4	-35.6	174.3	-173.9	-177.1	179.9	-173.1	0	113.3	Y483 V485 K491	Y483-K487 HydrophobicContact CE1-CD 4.24Å; Y483-K487 WeakPolarHBondContact O-CB 3.46Å; Y483-K487 PolarHBondContact O-N 2.89Å; V485-K487 VanDerWaalsContact C-N 3.31Å; V485-K487 PolarHBondContact O-N 3.49Å; K487-K491 PolarHBondContact O-N 2.99Å
488	R	86.8	Confident	88	Confident	105 Å²	105	68.2 Å²	68.2	40%	0.396	33%	0.33	S	S	.	.	H	α-helix	trans	-74	-39.4	174	-74.1	-169.9	-63.1	172.6	3.2	112.2	D399 Q484 V485 K486 K491 Y492	D399-R488 IonicContact OD1-NH1 3.24Å; D399-R488 PolarHBondContact OD1-NH1 3.36Å; D399-R488 VanDerWaalsContact OD1-NH1 3.1Å; D399-R488 WeakPolarHBondContact OD2-CD 3.41Å; D399-R488 IonicContact OD2-CZ 3.75Å; D399-R488 IonicContact OD2-NE 2.75Å; D399-R488 IonicContact OD2-NH1 3.1Å; D399-R488 PolarHBondContact OD2-NH1 2.93Å; Q484-R488 WeakPolarHBondContact O-CG 3.47Å; Q484-R488 PolarHBondContact O-N 2.96Å; V485-R488 PolarHBondContact O-N 2.98Å; K486-R488 VanDerWaalsContact C-N 3.35Å; K486-R488 PolarHBondContact O-N 2.91Å; R488-K491 WeakPolarHBondContact O-CB 3.48Å; R488-K491 PolarHBondContact O-N 3.37Å; R488-Y492 PolarHBondContact O-N 3.36Å
489	R	88.7	Confident	88.3	Confident	90 Å²	90	66 Å²	66	34%	0.34	32%	0.32	S	S	.	.	H	α-helix	trans	-61.2	-46.4	173.7	-176.2	61.3	175.5	173.9	2.5	111.8	E432 L436 V485 K486 K491 Y492 L493	E432-R489 WeakPolarHBondContact OE1-CG 3.31Å; E432-R489 IonicContact OE1-CZ 3.71Å; E432-R489 IonicContact OE1-NE 3.48Å; E432-R489 PolarHBondContact OE1-NE 3.5Å; E432-R489 IonicContact OE1-NH2 2.71Å; E432-R489 PolarHBondContact OE1-NH2 3.34Å; E432-R489 IonicContact OE2-CZ 2.69Å; E432-R489 IonicContact OE2-NE 3.56Å; E432-R489 IonicContact OE2-NH2 2.75Å; E432-R489 PolarHBondContact OE2-NH2 3.1Å; L436-R489 HydrophobicContact CD1-CB 4.1Å; L436-R489 HydrophobicContact CD1-CG 3.58Å; V485-R489 PolarHBondContact O-N 3.34Å; K486-R489 PolarHBondContact O-N 2.87Å; R489-K491 VanDerWaalsContact C-N 3.33Å; R489-K491 PolarHBondContact O-N 2.72Å; R489-Y492 VanDerWaalsContact NH1-CE1 3.34Å; R489-Y492 PolarHBondContact O-N 3.16Å; R489-Y492 VanDerWaalsContact O-N 3.15Å; R489-L493 HydrophobicContact CG-CD1 4.03Å; R489-L493 HydrophobicContact CG-CG 4.4Å; R489-L493 WeakPolarHBondContact O-CB 3.4Å; R489-L493 WeakPolarHBondContact O-CG 3.4Å; R489-L493 PolarHBondContact O-N 3.29Å
490	C	88.7	Confident	88.8	Confident	20 Å²	20	57.9 Å²	57.9	14%	0.135	29%	0.285	C	S	.	.	H	α-helix	trans	-55.3	-43.8	172.9	174.2	0	0	0	0	112.3	Y433 L440 K486 K494	Y433-C490 WeakPolarHBondContact CE2-O 3.48Å; L440-C490 HydrophobicContact CD1-CB 4.02Å; K486-C490 WeakPolarHBondContact O-CB 3.5Å; K486-C490 PolarHBondContact O-N 3.06Å; C490-K494 PolarHBondContact O-N 2.85Å; C490-K494 VanDerWaalsContact O-N 3.14Å
491	K	87.9	Confident	88.9	Confident	108 Å²	108	58.6 Å²	58.6	47%	0.47	28%	0.283	S	S	.	.	H	α-helix	trans	-60.9	-50.6	171.9	-77.2	-177.9	173.5	-170.7	0	112.7	L401 K487 R488 R489 K494 H495	L401-K491 HydrophobicContact CD1-CD 4.39Å; K487-K491 PolarHBondContact O-N 2.99Å; R488-K491 WeakPolarHBondContact O-CB 3.48Å; R488-K491 PolarHBondContact O-N 3.37Å; R489-K491 VanDerWaalsContact C-N 3.33Å; R489-K491 PolarHBondContact O-N 2.72Å; K491-K494 PolarHBondContact O-N 3.45Å; K491-H495 PolarHBondContact O-N 3.07Å; K491-H495 PolarHBondContact O-ND1 2.69Å
492	Y	88.3	Confident	89.1	Confident	62 Å²	62	59.5 Å²	59.5	24%	0.243	27%	0.272	C	S	.	.	H	α-helix	trans	-57.1	-50.4	-178.5	166.1	-90.5	0	0	0	110.8	N404 F406 R488 R489 K494 H495 K496	N404-Y492 WeakPolarHBondContact OD1-CD2 3.14Å; N404-Y492 WeakPolarHBondContact OD1-CE2 3.41Å; F406-Y492 HydrophobicContact CE1-CD2 4.49Å; F406-Y492 AromaticContact CE1-CE2 3.71Å; F406-Y492 HydrophobicContact CE1-CE2 3.71Å; F406-Y492 AromaticContact CE1-CZ 3.95Å; F406-Y492 HydrophobicContact CZ-CD2 4.07Å; F406-Y492 AromaticContact CZ-CE2 3.74Å; F406-Y492 HydrophobicContact CZ-CE2 3.74Å; R488-Y492 PolarHBondContact O-N 3.36Å; R489-Y492 VanDerWaalsContact NH1-CE1 3.34Å; R489-Y492 PolarHBondContact O-N 3.16Å; R489-Y492 VanDerWaalsContact O-N 3.15Å; Y492-K494 VanDerWaalsContact C-N 3.33Å; Y492-K494 PolarHBondContact O-N 2.9Å; Y492-H495 PolarHBondContact O-N 2.93Å; Y492-K496 HydrophobicContact CE1-CD 4.09Å; Y492-K496 PolarHBondContact O-N 3.02Å
493	L	90.3	Very high	89.1	Confident	0 Å²	0	55.3 Å²	55.3	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-56.9	-43.6	177.6	-70	170.1	0	0	0	111.7	D429 E432 Y433 L436 R489 H495 K496 L497	D429-L493 HydrophobicContact CB-CD2 4Å; E432-L493 HydrophobicContact CB-CD1 4.11Å; E432-L493 HydrophobicContact CG-CD1 4.02Å; Y433-L493 HydrophobicContact CD2-CB 3.99Å; L436-L493 HydrophobicContact CD1-CD1 3.8Å; R489-L493 HydrophobicContact CG-CD1 4.03Å; R489-L493 HydrophobicContact CG-CG 4.4Å; R489-L493 WeakPolarHBondContact O-CB 3.4Å; R489-L493 WeakPolarHBondContact O-CG 3.4Å; R489-L493 PolarHBondContact O-N 3.29Å; L493-H495 VanDerWaalsContact C-N 3.29Å; L493-H495 PolarHBondContact O-N 2.93Å; L493-K496 PolarHBondContact O-N 2.91Å; L493-L497 HydrophobicContact CB-CD1 4.5Å; L493-L497 VanDerWaalsContact O-CB 3.27Å; L493-L497 WeakPolarHBondContact O-CB 3.13Å; L493-L497 WeakPolarHBondContact O-CG 3.21Å; L493-L497 PolarHBondContact O-N 2.93Å
494	K	88.1	Confident	89.3	Confident	71 Å²	71	54.6 Å²	54.6	31%	0.309	25%	0.247	S	C	.	.	H	α-helix	trans	-59.6	-36.1	176.5	-176.5	160.2	-176.9	160.5	0	113.2	Y433 C490 K491 Y492 N498	Y433-K494 HydrophobicContact CD2-CB 4.39Å; Y433-K494 HydrophobicContact CE2-CB 3.79Å; C490-K494 PolarHBondContact O-N 2.85Å; C490-K494 VanDerWaalsContact O-N 3.14Å; K491-K494 PolarHBondContact O-N 3.45Å; Y492-K494 VanDerWaalsContact C-N 3.33Å; Y492-K494 PolarHBondContact O-N 2.9Å; K494-N498 VanDerWaalsContact O-CB 3.31Å; K494-N498 WeakPolarHBondContact O-CB 3.21Å; K494-N498 PolarHBondContact O-N 3.35Å; K494-N498 PolarHBondContact O-OD1 2.68Å
495	H	87.1	Confident	89.5	Confident	119 Å²	119	53.2 Å²	53.2	55%	0.551	25%	0.245	S	C	*	.	H	α-helix	trans	-74.8	-45.7	177.5	-66.1	73	0	0	0	111.2	F406 K491 Y492 L493 L497 N498 H499	F406-H495 HydrophobicContact CE2-CB 3.81Å; F406-H495 HydrophobicContact CZ-CB 4.4Å; K491-H495 PolarHBondContact O-N 3.07Å; K491-H495 PolarHBondContact O-ND1 2.69Å; Y492-H495 PolarHBondContact O-N 2.93Å; L493-H495 VanDerWaalsContact C-N 3.29Å; L493-H495 PolarHBondContact O-N 2.93Å; H495-L497 PolarHBondContact O-N 3.06Å; H495-N498 PolarHBondContact O-N 3.37Å; H495-H499 PolarHBondContact O-N 3.16Å
496	K	90.6	Very high	89.6	Confident	8 Å²	8	52.1 Å²	52.1	4%	0.035	24%	0.237	C	C	.	.	H	α-helix	trans	-56.5	-50.8	175.7	-174.5	-179.3	176.5	-176.3	0	111.8	F406 F410 E425 D429 Y492 L493 N498 H499 I500	F406-K496 HydrophobicContact CD1-CB 4.31Å; F406-K496 HydrophobicContact CD1-CG 4.22Å; F406-K496 HydrophobicContact CE1-CB 3.66Å; F406-K496 HydrophobicContact CE1-CD 4.44Å; F406-K496 HydrophobicContact CE1-CG 3.9Å; F406-K496 HydrophobicContact CZ-CB 3.77Å; F410-K496 HydrophobicContact CE2-CD 4.31Å; F410-K496 HydrophobicContact CE2-CG 4.23Å; E425-K496 IonicContact OE1-NZ 3.6Å; E425-K496 PolarHBondContact OE1-NZ 3.4Å; D429-K496 WeakPolarHBondContact OD2-CD 3.37Å; D429-K496 VanDerWaalsContact OD2-CE 3.31Å; D429-K496 WeakPolarHBondContact OD2-CE 3.42Å; D429-K496 IonicContact OD2-NZ 3.77Å; D429-K496 PolarHBondContact OD2-NZ 3.26Å; Y492-K496 HydrophobicContact CE1-CD 4.09Å; Y492-K496 PolarHBondContact O-N 3.02Å; L493-K496 PolarHBondContact O-N 2.91Å; K496-N498 PolarHBondContact O-N 3.26Å; K496-H499 PolarHBondContact O-N 3.17Å; K496-I500 HydrophobicContact CD-CD1 4.41Å; K496-I500 HydrophobicContact CG-CD1 3.82Å; K496-I500 HydrophobicContact CG-CG1 4.5Å; K496-I500 WeakPolarHBondContact O-CG1 3.37Å; K496-I500 PolarHBondContact O-N 3.17Å
497	L	92.4	Very high	89.7	Confident	8 Å²	8	51.5 Å²	51.5	4%	0.042	23%	0.234	C	C	.	.	H	α-helix	trans	-61.9	-42.9	179.6	-69.6	169.5	0	0	0	112.1	F426 D429 H430 Y433 L493 H495 H499 I500 K501	F426-L497 HydrophobicContact CB-CD2 4.42Å; F426-L497 HydrophobicContact CD2-CB 4.17Å; F426-L497 HydrophobicContact CD2-CD2 3.51Å; F426-L497 HydrophobicContact CD2-CG 4.47Å; F426-L497 HydrophobicContact CE2-CB 3.83Å; F426-L497 HydrophobicContact CE2-CD2 3.79Å; F426-L497 HydrophobicContact CE2-CG 4.4Å; F426-L497 WeakPolarHBondContact CE2-O 3.39Å; F426-L497 HydrophobicContact CG-CD2 3.95Å; F426-L497 HydrophobicContact CZ-CD2 4.45Å; F426-L497 WeakPolarHBondContact O-CD2 3.45Å; D429-L497 HydrophobicContact CB-CD2 3.91Å; H430-L497 HydrophobicContact CB-CD1 4.19Å; H430-L497 HydrophobicContact CB-CD2 4.06Å; Y433-L497 HydrophobicContact CG-CD1 4.05Å; L493-L497 HydrophobicContact CB-CD1 4.5Å; L493-L497 VanDerWaalsContact O-CB 3.27Å; L493-L497 WeakPolarHBondContact O-CB 3.13Å; L493-L497 WeakPolarHBondContact O-CG 3.21Å; L493-L497 PolarHBondContact O-N 2.93Å; H495-L497 PolarHBondContact O-N 3.06Å; L497-H499 VanDerWaalsContact C-N 3.32Å; L497-H499 PolarHBondContact O-N 3.39Å; L497-I500 PolarHBondContact O-N 3.24Å; L497-K501 WeakPolarHBondContact O-CB 3.39Å; L497-K501 PolarHBondContact O-N 2.96Å
498	N	90.3	Very high	89.8	Confident	84 Å²	84	49.7 Å²	49.7	45%	0.449	23%	0.228	S	C	.	.	H	α-helix	trans	-61.8	-39.6	175.7	-81.7	6.5	0	0	0	112.1	K494 H495 K496 K502	K494-N498 VanDerWaalsContact O-CB 3.31Å; K494-N498 WeakPolarHBondContact O-CB 3.21Å; K494-N498 PolarHBondContact O-N 3.35Å; K494-N498 PolarHBondContact O-OD1 2.68Å; H495-N498 PolarHBondContact O-N 3.37Å; K496-N498 PolarHBondContact O-N 3.26Å; N498-K502 WeakPolarHBondContact O-CB 3.49Å; N498-K502 PolarHBondContact O-N 2.96Å
499	H	89.3	Confident	89.9	Confident	22 Å²	22	52.8 Å²	52.8	10%	0.102	24%	0.24	C	C	.	.	H	α-helix	trans	-68.8	-46.4	176.7	-179	69.4	0	0	0	112.5	F406 D407 F410 H495 K496 L497 K501 K502 M503	F406-H499 HydrophobicContact CB-CB 4.17Å; F406-H499 WeakPolarHBondContact CB-CD2 3.41Å; F406-H499 HydrophobicContact CD2-CB 4.46Å; F406-H499 PolarHBondContact O-CD2 3.16Å; F406-H499 PolarHBondContact O-NE2 2.99Å; D407-H499 IonicContact OD1-CE1 2.63Å; D407-H499 PolarHBondContact OD1-CE1 3.05Å; D407-H499 IonicContact OD1-NE2 3.98Å; F410-H499 PolarHBondContact O-NE2 3.39Å; H495-H499 PolarHBondContact O-N 3.16Å; K496-H499 PolarHBondContact O-N 3.17Å; L497-H499 VanDerWaalsContact C-N 3.32Å; L497-H499 PolarHBondContact O-N 3.39Å; H499-K501 VanDerWaalsContact C-N 3.34Å; H499-K501 PolarHBondContact O-N 3.13Å; H499-K502 WeakPolarHBondContact O-CA 3.48Å; H499-K502 WeakPolarHBondContact O-CB 3.48Å; H499-K502 PolarHBondContact O-N 3.2Å; H499-K502 VanDerWaalsContact O-N 3.1Å; H499-M503 PolarHBondContact O-N 3.1Å
500	I	91.1	Very high	89.6	Confident	0 Å²	0	55.6 Å²	55.6	0%	0	25%	0.25	C	S	.	.	H	α-helix	trans	-61.4	-43.3	176.9	-64.7	170.5	0	0	0	110.8	F410 Y422 E425 F426 K496 L497 K502 M503 V504	F410-I500 HydrophobicContact CB-CG1 4.44Å; F410-I500 HydrophobicContact CD1-CD1 3.97Å; F410-I500 HydrophobicContact CD1-CG1 3.83Å; F410-I500 HydrophobicContact CD2-CD1 4.28Å; F410-I500 HydrophobicContact CD2-CG1 4.12Å; F410-I500 HydrophobicContact CE1-CD1 3.74Å; F410-I500 HydrophobicContact CE1-CG1 4.14Å; F410-I500 HydrophobicContact CE2-CD1 4.08Å; F410-I500 HydrophobicContact CE2-CG1 4.42Å; F410-I500 HydrophobicContact CG-CD1 4.25Å; F410-I500 HydrophobicContact CG-CG1 3.84Å; F410-I500 HydrophobicContact CZ-CD1 3.82Å; F410-I500 HydrophobicContact CZ-CG1 4.45Å; Y422-I500 HydrophobicContact CD2-CG2 4.36Å; Y422-I500 WeakPolarHBondContact O-CG2 3.5Å; E425-I500 HydrophobicContact CG-CD1 4.23Å; F426-I500 HydrophobicContact CB-CG2 3.95Å; F426-I500 HydrophobicContact CD2-CB 4.41Å; F426-I500 HydrophobicContact CD2-CG2 4.35Å; K496-I500 HydrophobicContact CD-CD1 4.41Å; K496-I500 HydrophobicContact CG-CD1 3.82Å; K496-I500 HydrophobicContact CG-CG1 4.5Å; K496-I500 WeakPolarHBondContact O-CG1 3.37Å; K496-I500 PolarHBondContact O-N 3.17Å; L497-I500 PolarHBondContact O-N 3.24Å; I500-K502 VanDerWaalsContact C-N 3.29Å; I500-K502 PolarHBondContact O-N 3.14Å; I500-M503 PolarHBondContact O-N 2.97Å; I500-V504 HydrophobicContact CG2-CG2 4.48Å; I500-V504 WeakPolarHBondContact O-CG2 3.47Å; I500-V504 PolarHBondContact O-N 3.17Å
501	K	92.1	Very high	88.7	Confident	56 Å²	56	61.1 Å²	61.1	24%	0.243	28%	0.284	C	S	.	.	H	α-helix	trans	-59.1	-39.9	174.2	-173.3	176.4	-174.6	179.7	0	111.9	D288 V289 F426 L497 H499 S505	D288-K501 PolarHBondContact O-NZ 2.94Å; V289-K501 HydrophobicContact CG2-CD 4.31Å; F426-K501 HydrophobicContact CD2-CB 4.45Å; F426-K501 HydrophobicContact CE2-CB 3.95Å; L497-K501 WeakPolarHBondContact O-CB 3.39Å; L497-K501 PolarHBondContact O-N 2.96Å; H499-K501 VanDerWaalsContact C-N 3.34Å; H499-K501 PolarHBondContact O-N 3.13Å; K501-S505 WeakPolarHBondContact O-CB 3.37Å; K501-S505 PolarHBondContact O-N 3.37Å
502	K	91.4	Very high	88.7	Confident	99 Å²	99	58.8 Å²	58.8	43%	0.43	27%	0.274	S	S	.	.	H	α-helix	trans	-62.7	-50.1	173.7	176.8	-161.9	162.1	-151.9	0	111	N498 H499 I500 V504 S505 D506	N498-K502 WeakPolarHBondContact O-CB 3.49Å; N498-K502 PolarHBondContact O-N 2.96Å; H499-K502 WeakPolarHBondContact O-CA 3.48Å; H499-K502 WeakPolarHBondContact O-CB 3.48Å; H499-K502 PolarHBondContact O-N 3.2Å; H499-K502 VanDerWaalsContact O-N 3.1Å; I500-K502 VanDerWaalsContact C-N 3.29Å; I500-K502 PolarHBondContact O-N 3.14Å; K502-V504 PolarHBondContact O-N 3.01Å; K502-S505 CarbonylContact O-C 3.48Å; K502-S505 PolarHBondContact O-N 3.38Å; K502-D506 WeakPolarHBondContact CG-OD2 3.5Å; K502-D506 WeakPolarHBondContact O-CB 3.41Å; K502-D506 VanDerWaalsContact O-CG 3.31Å; K502-D506 PolarHBondContact O-N 3.42Å
503	M	90.1	Very high	88.8	Confident	5 Å²	5	58.6 Å²	58.6	3%	0.025	28%	0.276	C	S	.	.	H	α-helix	trans	-58.9	-45.4	-179.8	-67.9	-56.9	96.2	0	0	112.3	P412 I413 Y422 H499 I500 D506 Y507	P412-M503 HydrophobicContact CB-SD 4.37Å; P412-M503 HydrophobicContact CG-SD 4.26Å; I413-M503 HydrophobicContact CD1-CB 4.01Å; I413-M503 HydrophobicContact CG1-CB 4.28Å; Y422-M503 HydrophobicContact CD2-CB 4.25Å; Y422-M503 HydrophobicContact CE2-CB 4.22Å; H499-M503 PolarHBondContact O-N 3.1Å; I500-M503 PolarHBondContact O-N 2.97Å; M503-D506 PolarHBondContact O-N 3.41Å; M503-Y507 PolarHBondContact O-N 3.31Å
504	V	91.6	Very high	88.7	Confident	2 Å²	2	61.8 Å²	61.8	1%	0.012	29%	0.291	C	S	.	.	H	α-helix	trans	-65	-44.5	176.1	178.7	0	0	0	0	111	W292 I413 R419 I500 K502 D506 Y507 D508	W292-V504 HydrophobicContact CH2-CG1 4.47Å; W292-V504 HydrophobicContact CZ2-CG1 3.87Å; I413-V504 HydrophobicContact CD1-CB 4.33Å; I413-V504 HydrophobicContact CD1-CG2 3.73Å; R419-V504 HydrophobicContact CG-CG1 4.03Å; I500-V504 HydrophobicContact CG2-CG2 4.48Å; I500-V504 WeakPolarHBondContact O-CG2 3.47Å; I500-V504 PolarHBondContact O-N 3.17Å; K502-V504 PolarHBondContact O-N 3.01Å; V504-D506 VanDerWaalsContact C-N 3.28Å; V504-D506 PolarHBondContact O-N 2.98Å; V504-Y507 WeakPolarHBondContact O-CB 3.35Å; V504-Y507 PolarHBondContact O-N 3Å; V504-Y507 VanDerWaalsContact O-N 3.12Å; V504-D508 WeakPolarHBondContact O-CB 3.46Å; V504-D508 VanDerWaalsContact O-CG 3.28Å; V504-D508 PolarHBondContact O-N 3.32Å
505	S	90	Very high	88.7	Confident	43 Å²	43	61.3 Å²	61.3	30%	0.301	29%	0.29	S	S	.	.	H	α-helix	trans	-66.3	-27.4	176.4	-174	0	0	0	0	113.7	K501 K502 R509	K501-S505 WeakPolarHBondContact O-CB 3.37Å; K501-S505 PolarHBondContact O-N 3.37Å; K502-S505 CarbonylContact O-C 3.48Å; K502-S505 PolarHBondContact O-N 3.38Å; S505-R509 WeakPolarHBondContact O-CB 3.25Å; S505-R509 VanDerWaalsContact O-CG 3.25Å; S505-R509 WeakPolarHBondContact O-CG 3.46Å; S505-R509 PolarHBondContact O-N 3.36Å; S505-R509 PolarHBondContact O-NE 2.81Å; S505-R509 VanDerWaalsContact OG-CZ 3.24Å; S505-R509 PolarHBondContact OG-NH2 2.85Å
506	D	90.2	Very high	88.8	Confident	53 Å²	53	57.7 Å²	57.7	28%	0.283	27%	0.274	S	S	.	.	H	α-helix	trans	-80	-22.4	174	-72.9	-19.1	0	0	0	111.9	K502 M503 V504 R509 R510	K502-D506 WeakPolarHBondContact CG-OD2 3.5Å; K502-D506 WeakPolarHBondContact O-CB 3.41Å; K502-D506 VanDerWaalsContact O-CG 3.31Å; K502-D506 PolarHBondContact O-N 3.42Å; M503-D506 PolarHBondContact O-N 3.41Å; V504-D506 VanDerWaalsContact C-N 3.28Å; V504-D506 PolarHBondContact O-N 2.98Å; D506-R509 IonicContact OD1-CZ 3.39Å; D506-R509 IonicContact OD1-NE 3.59Å; D506-R509 IonicContact OD1-NH2 2.72Å; D506-R509 PolarHBondContact OD1-NH2 3.01Å; D506-R510 WeakPolarHBondContact O-CG 3.24Å; D506-R510 PolarHBondContact O-NE 3.02Å
507	Y	92.1	Very high	88.7	Confident	32 Å²	32	61 Å²	61	13%	0.125	29%	0.29	C	S	.	.	H	α-helix	trans	-73.6	-52.6	166.1	-171.9	-101.9	0	0	0	111.5	I413 A414 E416 R419 M503 V504 R509 R510 T511	I413-Y507 HydrophobicContact CB-CD2 4.04Å; I413-Y507 HydrophobicContact CB-CG 4.27Å; I413-Y507 HydrophobicContact CG2-CD1 4.5Å; I413-Y507 HydrophobicContact CG2-CD2 3.6Å; I413-Y507 HydrophobicContact CG2-CE2 4.03Å; I413-Y507 HydrophobicContact CG2-CG 3.86Å; I413-Y507 WeakPolarHBondContact O-CD2 3.44Å; A414-Y507 WeakPolarHBondContact O-CE2 3.33Å; E416-Y507 PolarHBondContact N-OH 3Å; R419-Y507 HydrophobicContact CB-CD1 4.11Å; R419-Y507 HydrophobicContact CB-CE1 4.25Å; R419-Y507 HydrophobicContact CG-CD1 3.92Å; R419-Y507 HydrophobicContact CG-CE1 4.38Å; M503-Y507 PolarHBondContact O-N 3.31Å; V504-Y507 WeakPolarHBondContact O-CB 3.35Å; V504-Y507 PolarHBondContact O-N 3Å; V504-Y507 VanDerWaalsContact O-N 3.12Å; Y507-R509 PolarHBondContact O-N 3.47Å; Y507-R510 PolarHBondContact O-N 3.27Å; Y507-T511 HydrophobicContact CE1-CG2 3.96Å; Y507-T511 HydrophobicContact CE2-CG2 4.23Å; Y507-T511 PolarHBondContact O-N 3.2Å; Y507-T511 PolarHBondContact O-OG1 3.5Å
508	D	88.8	Confident	88.4	Confident	56 Å²	56	64.8 Å²	64.8	30%	0.299	31%	0.308	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.2	-1.6	-179.1	-64.8	2.5	0	0	0	114.2	R419 V504	R419-D508 IonicContact CZ-OD1 3.59Å; R419-D508 IonicContact CZ-OD2 3.61Å; R419-D508 IonicContact NE-OD1 3.98Å; R419-D508 PolarHBondContact NE-OD1 3.12Å; R419-D508 IonicContact NE-OD2 3.5Å; R419-D508 IonicContact NH2-OD1 2.66Å; R419-D508 PolarHBondContact NH2-OD1 3.05Å; R419-D508 IonicContact NH2-OD2 2.75Å; R419-D508 PolarHBondContact NH2-OD2 3.21Å; V504-D508 WeakPolarHBondContact O-CB 3.46Å; V504-D508 VanDerWaalsContact O-CG 3.28Å; V504-D508 PolarHBondContact O-N 3.32Å
509	R	89.3	Confident	88.3	Confident	171 Å²	171	63.3 Å²	63.3	65%	0.645	30%	0.297	S	S	*	.	T	Hydrogen-bonded Turn	trans	-110.9	-2.4	172.5	-73.6	-175.4	-69.8	-146.4	3.7	114	S505 D506 Y507	S505-R509 WeakPolarHBondContact O-CB 3.25Å; S505-R509 VanDerWaalsContact O-CG 3.25Å; S505-R509 WeakPolarHBondContact O-CG 3.46Å; S505-R509 PolarHBondContact O-N 3.36Å; S505-R509 PolarHBondContact O-NE 2.81Å; S505-R509 VanDerWaalsContact OG-CZ 3.24Å; S505-R509 PolarHBondContact OG-NH2 2.85Å; D506-R509 IonicContact OD1-CZ 3.39Å; D506-R509 IonicContact OD1-NE 3.59Å; D506-R509 IonicContact OD1-NH2 2.72Å; D506-R509 PolarHBondContact OD1-NH2 3.01Å; Y507-R509 PolarHBondContact O-N 3.47Å
510	R	82.9	Confident	88.2	Confident	148 Å²	148	66.8 Å²	66.8	56%	0.558	31%	0.313	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.9	-31	178.6	-76.6	-178.4	-71.4	147.8	2.1	112.7	I413 D506 Y507	I413-R510 PolarHBondContact O-NH1 3.44Å; I413-R510 PolarHBondContact O-NH2 2.92Å; D506-R510 WeakPolarHBondContact O-CG 3.24Å; D506-R510 PolarHBondContact O-NE 3.02Å; Y507-R510 PolarHBondContact O-N 3.27Å
511	T	68.7	Low	87.9	Confident	136 Å²	136	72.8 Å²	72.8	83%	0.834	34%	0.342	S	S	*	.			trans	-88.1	0	168.4	53.9	0	0	0	0	110.6	Y507	Y507-T511 HydrophobicContact CE1-CG2 3.96Å; Y507-T511 HydrophobicContact CE2-CG2 4.23Å; Y507-T511 PolarHBondContact O-N 3.2Å; Y507-T511 PolarHBondContact O-OG1 3.5Å

Retrieved 511 of 511 residues in 379.8 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).