A0A087XRK5_POEFO Loading...

Pyruvate carboxylase

AlphaFold DB , UniProt , Accession A0A087XRK5, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 678 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1Q56.8Low85.1Confident251 Ų25186.5 Ų86.5100%1.17344%0.444SS*.  01430-71.2-176.9-11.400107.7
2T79.8Confident85.5Confident94 Ų9486.6 Ų86.658%0.57746%0.458SS*.  trans-131.4162.917964.60000108.9I4T2-I4 HydrophobicContact CG2-CD1 4.45Å; T2-I4 PolarHBondContact O-N 3.48Å; T2-I4 WeakPolarHBondContact OG1-CG1 3.2Å; T2-I4 PolarHBondContact OG1-N 3Å
3N87.2Confident86Confident104 Ų10481.5 Ų81.556%0.55643%0.431SS*.SBendtrans-81.37.417364.5-17.5000113.1F6 L7N3-F6 WeakPolarHBondContact O-CB 3.41Å; N3-F6 PolarHBondContact O-N 2.69Å; N3-L7 WeakPolarHBondContact O-CG 2.94Å; N3-L7 PolarHBondContact O-N 3.4Å
4I85.8Confident86.4Confident90 Ų9083.9 Ų83.946%0.46244%0.444SS..Hα-helixtrans-57.5-47.1-175.6-67171.9000112.3T2 F6 L7 Q8T2-I4 HydrophobicContact CG2-CD1 4.45Å; T2-I4 PolarHBondContact O-N 3.48Å; T2-I4 WeakPolarHBondContact OG1-CG1 3.2Å; T2-I4 PolarHBondContact OG1-N 3Å; I4-F6 VanDerWaalsContact C-N 3.27Å; I4-F6 PolarHBondContact O-N 3.25Å; I4-L7 PolarHBondContact O-N 2.78Å; I4-L7 VanDerWaalsContact O-N 3.14Å; I4-Q8 HydrophobicContact CG2-CG 4.35Å; I4-Q8 WeakPolarHBondContact O-CG 3.4Å; I4-Q8 PolarHBondContact O-N 3.14Å
5P84.3Confident86.7Confident25 Ų2583.1 Ų83.116%0.16244%0.437CS..Hα-helixtrans-61.7-35.8179.2-24.235.9000112.8Q8 N9 L35P5-Q8 PolarHBondContact O-N 2.84Å; P5-N9 PolarHBondContact O-N 3.5Å; P5-N9 VanDerWaalsContact O-N 3.08Å; P5-L35 HydrophobicContact CB-CB 4.33Å; P5-L35 HydrophobicContact CB-CD2 4.18Å
6F90.4Very high87.1Confident39 Ų3982.9 Ų82.917%0.17143%0.432CS..Hα-helixtrans-65-46174.5171.9-100.9000111N3 I4 Q8 N9 V10 I26 L32 F33 L35N3-F6 WeakPolarHBondContact O-CB 3.41Å; N3-F6 PolarHBondContact O-N 2.69Å; I4-F6 VanDerWaalsContact C-N 3.27Å; I4-F6 PolarHBondContact O-N 3.25Å; F6-Q8 VanDerWaalsContact C-N 3.31Å; F6-Q8 PolarHBondContact O-N 3.19Å; F6-N9 WeakPolarHBondContact O-CB 3.33Å; F6-N9 PolarHBondContact O-N 2.65Å; F6-V10 HydrophobicContact CD1-CG2 4.34Å; F6-V10 HydrophobicContact CE1-CG2 3.9Å; F6-V10 HydrophobicContact CE2-CG2 4.22Å; F6-V10 HydrophobicContact CZ-CG2 3.83Å; F6-V10 WeakPolarHBondContact O-CG2 3.3Å; F6-V10 PolarHBondContact O-N 2.69Å; F6-I26 HydrophobicContact CE2-CG2 4.35Å; F6-I26 HydrophobicContact CZ-CD1 4.07Å; F6-I26 HydrophobicContact CZ-CG1 4.28Å; F6-I26 HydrophobicContact CZ-CG2 4.05Å; F6-L32 HydrophobicContact CD2-CB 4.3Å; F6-L32 HydrophobicContact CE2-CB 3.91Å; F6-F33 HydrophobicContact CD2-CD1 4.29Å; F6-F33 HydrophobicContact CD2-CE1 4.16Å; F6-F33 HydrophobicContact CE2-CD1 4.33Å; F6-F33 AromaticContact CE2-CE1 3.86Å; F6-F33 HydrophobicContact CE2-CE1 3.86Å; F6-F33 HydrophobicContact CE2-CE2 4.32Å; F6-F33 AromaticContact CE2-CZ 3.86Å; F6-F33 HydrophobicContact CE2-CZ 3.86Å; F6-L35 HydrophobicContact CB-CD2 3.89Å
7L90.3Very high87.3Confident77 Ų7784.1 Ų84.140%0.40344%0.438SS..Hα-helixtrans-62.5-37176.4-67.6175.5000112.2N3 I4 V10 L11N3-L7 WeakPolarHBondContact O-CG 2.94Å; N3-L7 PolarHBondContact O-N 3.4Å; I4-L7 PolarHBondContact O-N 2.78Å; I4-L7 VanDerWaalsContact O-N 3.14Å; L7-V10 PolarHBondContact O-N 2.95Å; L7-L11 WeakPolarHBondContact O-CB 3.49Å; L7-L11 WeakPolarHBondContact O-CG 3.19Å; L7-L11 PolarHBondContact O-N 3.29Å
8Q88.6Confident87.6Confident107 Ų10786.9 Ų86.950%0.545%0.448SS..Hα-helixtrans-63.1-42.6174.3-73.1176.6-41.100111.8I4 P5 F6 L11 S12I4-Q8 HydrophobicContact CG2-CG 4.35Å; I4-Q8 WeakPolarHBondContact O-CG 3.4Å; I4-Q8 PolarHBondContact O-N 3.14Å; P5-Q8 PolarHBondContact O-N 2.84Å; F6-Q8 VanDerWaalsContact C-N 3.31Å; F6-Q8 PolarHBondContact O-N 3.19Å; Q8-L11 PolarHBondContact O-N 3.5Å; Q8-S12 WeakPolarHBondContact O-CB 3.16Å; Q8-S12 PolarHBondContact O-N 3.43Å; Q8-S12 PolarHBondContact O-OG 3.23Å
9N91.2Very high87.7Confident47 Ų4787.8 Ų87.825%0.25146%0.463SS..Hα-helixtrans-62.4-43.3174.9-72.7-8.6000111.2P5 F6 S12 N13 L32 N34P5-N9 PolarHBondContact O-N 3.5Å; P5-N9 VanDerWaalsContact O-N 3.08Å; F6-N9 WeakPolarHBondContact O-CB 3.33Å; F6-N9 PolarHBondContact O-N 2.65Å; N9-S12 PolarHBondContact O-N 3.29Å; N9-N13 PolarHBondContact O-N 3.33Å; N9-L32 HydrophobicContact CB-CD2 4.06Å; N9-L32 PolarHBondContact ND2-O 2.99Å; N9-N34 PolarHBondContact ND2-O 3.39Å; N9-N34 VanDerWaalsContact ND2-O 3.11Å
10V91.1Very high87.8Confident14 Ų1488.1 Ų88.19%0.08547%0.469CS..Hα-helixtrans-59.7-50.2175.1169.50000111.1F6 L7 S12 N13 F16 F25 L32F6-V10 HydrophobicContact CD1-CG2 4.34Å; F6-V10 HydrophobicContact CE1-CG2 3.9Å; F6-V10 HydrophobicContact CE2-CG2 4.22Å; F6-V10 HydrophobicContact CZ-CG2 3.83Å; F6-V10 WeakPolarHBondContact O-CG2 3.3Å; F6-V10 PolarHBondContact O-N 2.69Å; L7-V10 PolarHBondContact O-N 2.95Å; V10-S12 PolarHBondContact O-N 3Å; V10-N13 PolarHBondContact O-N 3.11Å; V10-F16 HydrophobicContact CG1-CD1 4.34Å; V10-F16 HydrophobicContact CG1-CD2 3.51Å; V10-F16 HydrophobicContact CG1-CE1 4.45Å; V10-F16 HydrophobicContact CG1-CE2 3.62Å; V10-F16 HydrophobicContact CG1-CG 3.89Å; V10-F16 HydrophobicContact CG1-CZ 4.1Å; V10-F16 WeakPolarHBondContact O-CB 3.39Å; V10-F16 WeakPolarHBondContact O-CG 3.36Å; V10-F25 HydrophobicContact CG1-CE1 4.12Å; V10-F25 HydrophobicContact CG2-CE1 4.49Å; V10-L32 HydrophobicContact CG2-CD1 4.09Å; V10-L32 HydrophobicContact CG2-CD2 4.11Å
11L91Very high88Confident104 Ų10486.7 Ų86.755%0.54546%0.463SS..Hα-helixtrans-66.7-18.6-179.4-68.6174.2000113.6L7 Q8 F16 L17L7-L11 WeakPolarHBondContact O-CB 3.49Å; L7-L11 WeakPolarHBondContact O-CG 3.19Å; L7-L11 PolarHBondContact O-N 3.29Å; Q8-L11 PolarHBondContact O-N 3.5Å; L11-F16 HydrophobicContact CD2-CD1 4.27Å; L11-F16 HydrophobicContact CD2-CE1 3.61Å; L11-F16 HydrophobicContact CD2-CZ 4.3Å; L11-L17 WeakPolarHBondContact O-CD2 3.32Å
12S89.3Confident89.6Confident87 Ų8779.4 Ų79.461%0.60843%0.432SS*.Hα-helixtrans-99-8.5178.6-510000113Q8 N9 V10Q8-S12 WeakPolarHBondContact O-CB 3.16Å; Q8-S12 PolarHBondContact O-N 3.43Å; Q8-S12 PolarHBondContact O-OG 3.23Å; N9-S12 PolarHBondContact O-N 3.29Å; V10-S12 PolarHBondContact O-N 3Å
13N92.6Very high90.1Very high20 Ų2081.7 Ų81.711%0.10745%0.446CS..  trans-74.2133.6-179.3-179.3-65.2000110.2N9 V10 Q15 F16 L17 F25 N29 E31 L32N9-N13 PolarHBondContact O-N 3.33Å; V10-N13 PolarHBondContact O-N 3.11Å; N13-Q15 VanDerWaalsContact C-N 3.31Å; N13-Q15 PolarHBondContact O-N 3.36Å; N13-Q15 WeakPolarHBondContact OD1-CB 3.36Å; N13-Q15 PolarHBondContact OD1-N 2.91Å; N13-F16 HydrophobicContact CB-CB 4.38Å; N13-F16 WeakPolarHBondContact O-CB 3.11Å; N13-F16 PolarHBondContact O-N 2.87Å; N13-F16 VanDerWaalsContact O-N 3.15Å; N13-L17 WeakPolarHBondContact O-CG 3.36Å; N13-L17 PolarHBondContact O-N 3.46Å; N13-F25 HydrophobicContact CB-CE2 4.47Å; N13-F25 HydrophobicContact CB-CZ 4.06Å; N13-F25 WeakPolarHBondContact OD1-CE2 3.35Å; N13-N29 PolarHBondContact ND2-OD1 3.07Å; N13-N29 VanDerWaalsContact ND2-OD1 3.17Å; N13-E31 PolarHBondContact ND2-OE1 2.94Å; N13-L32 HydrophobicContact CB-CD2 4.04Å
14N91.5Very high90.2Very high116 Ų11681.8 Ų81.862%0.6244%0.443SS*.Hα-helixtrans-59.9-37.2-176.7-84.6-32.7000113.4F16 L17 H18N14-F16 VanDerWaalsContact C-N 3.33Å; N14-L17 PolarHBondContact O-N 3.25Å; N14-H18 PolarHBondContact O-N 3.15Å; N14-H18 VanDerWaalsContact O-N 3.13Å; N14-H18 PolarHBondContact O-ND1 3.11Å
15Q90.8Very high90.6Very high71 Ų7178.1 Ų78.133%0.33242%0.424SS..Hα-helixtrans-64.8-41.7178.1-61.6-178.1000110.5N13 H18 S19 T20 V21 F25 N29N13-Q15 VanDerWaalsContact C-N 3.31Å; N13-Q15 PolarHBondContact O-N 3.36Å; N13-Q15 WeakPolarHBondContact OD1-CB 3.36Å; N13-Q15 PolarHBondContact OD1-N 2.91Å; Q15-H18 PolarHBondContact O-N 2.99Å; Q15-S19 PolarHBondContact O-N 3.32Å; Q15-T20 WeakPolarHBondContact CA-OG1 3.46Å; Q15-T20 PolarHBondContact O-N 3.07Å; Q15-T20 PolarHBondContact O-OG1 3Å; Q15-V21 HydrophobicContact CB-CG1 3.99Å; Q15-F25 HydrophobicContact CB-CD2 4.21Å; Q15-F25 HydrophobicContact CB-CE2 3.9Å; Q15-N29 PolarHBondContact OE1-ND2 2.9Å; Q15-N29 VanDerWaalsContact OE1-ND2 3.1Å
16F92.4Very high90.9Very high81 Ų8180.3 Ų80.336%0.35543%0.434SS..Hα-helixtrans-64.9-44.3176.7-165.6-89.3000112.1V10 L11 N13 N14 H18 S19 V21 F25V10-F16 HydrophobicContact CG1-CD1 4.34Å; V10-F16 HydrophobicContact CG1-CD2 3.51Å; V10-F16 HydrophobicContact CG1-CE1 4.45Å; V10-F16 HydrophobicContact CG1-CE2 3.62Å; V10-F16 HydrophobicContact CG1-CG 3.89Å; V10-F16 HydrophobicContact CG1-CZ 4.1Å; V10-F16 WeakPolarHBondContact O-CB 3.39Å; V10-F16 WeakPolarHBondContact O-CG 3.36Å; L11-F16 HydrophobicContact CD2-CD1 4.27Å; L11-F16 HydrophobicContact CD2-CE1 3.61Å; L11-F16 HydrophobicContact CD2-CZ 4.3Å; N13-F16 HydrophobicContact CB-CB 4.38Å; N13-F16 WeakPolarHBondContact O-CB 3.11Å; N13-F16 PolarHBondContact O-N 2.87Å; N13-F16 VanDerWaalsContact O-N 3.15Å; N14-F16 VanDerWaalsContact C-N 3.33Å; F16-H18 VanDerWaalsContact C-N 3.29Å; F16-H18 PolarHBondContact O-N 3.24Å; F16-S19 PolarHBondContact O-N 2.89Å; F16-V21 HydrophobicContact CB-CG1 4.22Å; F16-V21 HydrophobicContact CD2-CG1 4.32Å; F16-F25 HydrophobicContact CB-CE1 4.47Å; F16-F25 HydrophobicContact CB-CZ 4.02Å; F16-F25 HydrophobicContact CD2-CE1 4.06Å; F16-F25 HydrophobicContact CD2-CZ 4.45Å
17L91.4Very high90.8Very high103 Ų10385 Ų8554%0.53946%0.461SS..Hα-helixtrans-61.2-35178.3-73.1172000113.3L11 N13 N14 S19L11-L17 WeakPolarHBondContact O-CD2 3.32Å; N13-L17 WeakPolarHBondContact O-CG 3.36Å; N13-L17 PolarHBondContact O-N 3.46Å; N14-L17 PolarHBondContact O-N 3.25Å; L17-S19 VanDerWaalsContact C-N 3.35Å
18H93Very high90.9Very high134 Ų13486.6 Ų86.662%0.6247%0.466SS*.THydrogen-bonded Turntrans-93.88-179.6-63.985.8000113.2N14 Q15 F16 T20N14-H18 PolarHBondContact O-N 3.15Å; N14-H18 VanDerWaalsContact O-N 3.13Å; N14-H18 PolarHBondContact O-ND1 3.11Å; Q15-H18 PolarHBondContact O-N 2.99Å; F16-H18 VanDerWaalsContact C-N 3.29Å; F16-H18 PolarHBondContact O-N 3.24Å; H18-T20 HydrophobicContact CB-CG2 4.21Å; H18-T20 PolarHBondContact O-N 3.25Å
19S88.7Confident90.9Very high104 Ų10482 Ų8273%0.72745%0.445SS*.THydrogen-bonded Turntrans56.626.4-177.4-52.60000113.9Q15 F16 L17 V21Q15-S19 PolarHBondContact O-N 3.32Å; F16-S19 PolarHBondContact O-N 2.89Å; L17-S19 VanDerWaalsContact C-N 3.35Å; S19-V21 VanDerWaalsContact C-N 3.29Å; S19-V21 PolarHBondContact O-N 3.18Å
20T90.3Very high90.8Very high94 Ų9484.1 Ų84.158%0.57746%0.461SS*.  trans-96.352.1176.162.80000110Q15 H18Q15-T20 WeakPolarHBondContact CA-OG1 3.46Å; Q15-T20 PolarHBondContact O-N 3.07Å; Q15-T20 PolarHBondContact O-OG1 3Å; H18-T20 HydrophobicContact CB-CG2 4.21Å; H18-T20 PolarHBondContact O-N 3.25Å
21V90.8Very high90.6Very high58 Ų5888 Ų8835%0.35248%0.478SS..  trans-120.6144.8-177.7-62.70000110.4Q15 F16 S19 F25Q15-V21 HydrophobicContact CB-CG1 3.99Å; F16-V21 HydrophobicContact CB-CG1 4.22Å; F16-V21 HydrophobicContact CD2-CG1 4.32Å; S19-V21 VanDerWaalsContact C-N 3.29Å; S19-V21 PolarHBondContact O-N 3.18Å; V21-F25 HydrophobicContact CB-CB 3.96Å; V21-F25 HydrophobicContact CB-CD1 4.35Å; V21-F25 HydrophobicContact CB-CD2 4.15Å; V21-F25 HydrophobicContact CB-CG 3.88Å; V21-F25 HydrophobicContact CG1-CB 4.25Å; V21-F25 HydrophobicContact CG1-CD1 4.07Å; V21-F25 HydrophobicContact CG1-CD2 3.49Å; V21-F25 VanDerWaalsContact CG1-CD2 3.49Å; V21-F25 HydrophobicContact CG1-CE1 4.33Å; V21-F25 HydrophobicContact CG1-CE2 3.8Å; V21-F25 HydrophobicContact CG1-CG 3.64Å; V21-F25 HydrophobicContact CG1-CZ 4.21Å
22D91.4Very high90.5Very high99 Ų9983.2 Ų83.253%0.52945%0.453SS..  trans-126.6-167.617268.320.9000110.9Q24 F25D22-Q24 PolarHBondContact O-N 3.22Å; D22-Q24 WeakPolarHBondContact OD1-CA 3.48Å; D22-Q24 WeakPolarHBondContact OD1-CB 3.4Å; D22-Q24 PolarHBondContact OD1-N 3.44Å; D22-F25 VanDerWaalsContact O-CB 3.29Å; D22-F25 WeakPolarHBondContact O-CB 3.48Å; D22-F25 PolarHBondContact O-N 3.38Å; D22-F25 PolarHBondContact OD1-N 3.06Å
23T89.5Confident90.4Very high141 Ų14184.9 Ų84.987%0.86545%0.45SS*.THydrogen-bonded Turntrans-67.9-16.9-179.351.80000114.1
24Q91Very high90Very high107 Ų10789.3 Ų89.350%0.547%0.474SS..THydrogen-bonded Turntrans-94.7-9178.7-58.4-169.710.400112.8D22 I26 D27 E28D22-Q24 PolarHBondContact O-N 3.22Å; D22-Q24 WeakPolarHBondContact OD1-CA 3.48Å; D22-Q24 WeakPolarHBondContact OD1-CB 3.4Å; D22-Q24 PolarHBondContact OD1-N 3.44Å; Q24-I26 VanDerWaalsContact C-N 3.28Å; Q24-I26 PolarHBondContact O-N 2.97Å; Q24-D27 WeakPolarHBondContact O-CA 3.26Å; Q24-D27 PolarHBondContact O-N 3.24Å; Q24-E28 HydrophobicContact CB-CG 4.12Å; Q24-E28 PolarHBondContact O-N 2.84Å
25F92.4Very high89.5Confident12 Ų1287.5 Ų87.55%0.05346%0.463CS..Hα-helixtrans-42.4-47.7-178.7167.7-112.2000114.6V10 N13 Q15 F16 V21 D22 N29 L32V10-F25 HydrophobicContact CG1-CE1 4.12Å; V10-F25 HydrophobicContact CG2-CE1 4.49Å; N13-F25 HydrophobicContact CB-CE2 4.47Å; N13-F25 HydrophobicContact CB-CZ 4.06Å; N13-F25 WeakPolarHBondContact OD1-CE2 3.35Å; Q15-F25 HydrophobicContact CB-CD2 4.21Å; Q15-F25 HydrophobicContact CB-CE2 3.9Å; F16-F25 HydrophobicContact CB-CE1 4.47Å; F16-F25 HydrophobicContact CB-CZ 4.02Å; F16-F25 HydrophobicContact CD2-CE1 4.06Å; F16-F25 HydrophobicContact CD2-CZ 4.45Å; V21-F25 HydrophobicContact CB-CB 3.96Å; V21-F25 HydrophobicContact CB-CD1 4.35Å; V21-F25 HydrophobicContact CB-CD2 4.15Å; V21-F25 HydrophobicContact CB-CG 3.88Å; V21-F25 HydrophobicContact CG1-CB 4.25Å; V21-F25 HydrophobicContact CG1-CD1 4.07Å; V21-F25 HydrophobicContact CG1-CD2 3.49Å; V21-F25 VanDerWaalsContact CG1-CD2 3.49Å; V21-F25 HydrophobicContact CG1-CE1 4.33Å; V21-F25 HydrophobicContact CG1-CE2 3.8Å; V21-F25 HydrophobicContact CG1-CG 3.64Å; V21-F25 HydrophobicContact CG1-CZ 4.21Å; D22-F25 VanDerWaalsContact O-CB 3.29Å; D22-F25 WeakPolarHBondContact O-CB 3.48Å; D22-F25 PolarHBondContact O-N 3.38Å; D22-F25 PolarHBondContact OD1-N 3.06Å; F25-N29 VanDerWaalsContact CD2-ND2 3.27Å; F25-N29 WeakPolarHBondContact CD2-ND2 3.49Å; F25-N29 HydrophobicContact CE2-CB 4.42Å; F25-N29 WeakPolarHBondContact O-CB 3.37Å; F25-N29 PolarHBondContact O-N 3.33Å; F25-N29 PolarHBondContact O-ND2 3.13Å; F25-L32 HydrophobicContact CE1-CD1 3.88Å; F25-L32 HydrophobicContact CZ-CD1 3.89Å; F25-L32 HydrophobicContact CZ-CD2 4.46Å
26I90.8Very high88.4Confident71 Ų7192.1 Ų92.136%0.36448%0.482SS..Hα-helixtrans-68.2-37.7-178.3-65.4171.4000111.5F6 Q24 L32 F33F6-I26 HydrophobicContact CE2-CG2 4.35Å; F6-I26 HydrophobicContact CZ-CD1 4.07Å; F6-I26 HydrophobicContact CZ-CG1 4.28Å; F6-I26 HydrophobicContact CZ-CG2 4.05Å; Q24-I26 VanDerWaalsContact C-N 3.28Å; Q24-I26 PolarHBondContact O-N 2.97Å; I26-L32 HydrophobicContact CG1-CD1 4.49Å; I26-F33 HydrophobicContact CG2-CE2 3.88Å; I26-F33 HydrophobicContact CG2-CZ 3.72Å
27D89.7Confident87.1Confident138 Ų13894 Ų9474%0.73850%0.503SS*.Hα-helixtrans-74.2-31.2-178.4-65.2-26.2000111.6Q24Q24-D27 WeakPolarHBondContact O-CA 3.26Å; Q24-D27 PolarHBondContact O-N 3.24Å
28E90.9Very high85.9Confident111 Ų11194.6 Ų94.652%0.51951%0.511SS..Hα-helixtrans-82.5-14.4179.2-66.6-175.9157.300114Q24 P30Q24-E28 HydrophobicContact CB-CG 4.12Å; Q24-E28 PolarHBondContact O-N 2.84Å; E28-P30 VanDerWaalsContact C-CD 3.41Å; E28-P30 WeakPolarHBondContact O-CD 3.29Å
29N88.6Confident84.7Confident11 Ų1195.3 Ų95.36%0.05951%0.514CS..  trans-118.268.9-177.4-68.5-98.8000110.7N13 Q15 F25 E31 L32N13-N29 PolarHBondContact ND2-OD1 3.07Å; N13-N29 VanDerWaalsContact ND2-OD1 3.17Å; Q15-N29 PolarHBondContact OE1-ND2 2.9Å; Q15-N29 VanDerWaalsContact OE1-ND2 3.1Å; F25-N29 VanDerWaalsContact CD2-ND2 3.27Å; F25-N29 WeakPolarHBondContact CD2-ND2 3.49Å; F25-N29 HydrophobicContact CE2-CB 4.42Å; F25-N29 WeakPolarHBondContact O-CB 3.37Å; F25-N29 PolarHBondContact O-N 3.33Å; F25-N29 PolarHBondContact O-ND2 3.13Å; N29-E31 VanDerWaalsContact CA-OE2 3.23Å; N29-E31 WeakPolarHBondContact CA-OE2 3.41Å; N29-E31 VanDerWaalsContact CB-OE1 3.3Å; N29-E31 WeakPolarHBondContact CB-OE1 3.48Å; N29-E31 PolarHBondContact O-N 3.41Å; N29-E31 VanDerWaalsContact O-N 3.1Å; N29-E31 PolarHBondContact OD1-OE1 3.39Å; N29-E31 VanDerWaalsContact OD1-OE1 3.09Å; N29-L32 HydrophobicContact CB-CD1 3.78Å; N29-L32 HydrophobicContact CB-CG 3.87Å; N29-L32 WeakPolarHBondContact O-CB 3.32Å; N29-L32 VanDerWaalsContact O-CG 3.23Å; N29-L32 WeakPolarHBondContact O-CG 3.49Å; N29-L32 PolarHBondContact O-N 3.1Å
30P89.6Confident84.2Confident91 Ų9194.7 Ų94.759%0.59150%0.503SS*.G310 helixtrans-61.4-20.9-176.525.8-34.9000113.5E28 L32 F33E28-P30 VanDerWaalsContact C-CD 3.41Å; E28-P30 WeakPolarHBondContact O-CD 3.29Å; P30-L32 PolarHBondContact O-N 2.97Å; P30-F33 PolarHBondContact O-N 3.03Å; P30-F33 VanDerWaalsContact O-N 3.14Å
31E87Confident84Confident95 Ų9593.3 Ų93.344%0.44449%0.487SS..G310 helixtrans-64.1-19.3174.975.6-73.3174.500113.6N13 N29 F33 N34N13-E31 PolarHBondContact ND2-OE1 2.94Å; N29-E31 VanDerWaalsContact CA-OE2 3.23Å; N29-E31 WeakPolarHBondContact CA-OE2 3.41Å; N29-E31 VanDerWaalsContact CB-OE1 3.3Å; N29-E31 WeakPolarHBondContact CB-OE1 3.48Å; N29-E31 PolarHBondContact O-N 3.41Å; N29-E31 VanDerWaalsContact O-N 3.1Å; N29-E31 PolarHBondContact OD1-OE1 3.39Å; N29-E31 VanDerWaalsContact OD1-OE1 3.09Å; E31-F33 PolarHBondContact O-N 3.32Å; E31-F33 VanDerWaalsContact O-N 3.16Å; E31-N34 VanDerWaalsContact O-CB 3.26Å; E31-N34 WeakPolarHBondContact O-CB 3.4Å; E31-N34 PolarHBondContact O-N 3.36Å
32L88.1Confident83.8Confident3 Ų391.5 Ų91.52%0.01648%0.478CS..G310 helixtrans-58.9-26.1172.4-64.1175.6000112.2F6 N9 V10 N13 F25 I26 N29 P30 N34 L35F6-L32 HydrophobicContact CD2-CB 4.3Å; F6-L32 HydrophobicContact CE2-CB 3.91Å; N9-L32 HydrophobicContact CB-CD2 4.06Å; N9-L32 PolarHBondContact ND2-O 2.99Å; V10-L32 HydrophobicContact CG2-CD1 4.09Å; V10-L32 HydrophobicContact CG2-CD2 4.11Å; N13-L32 HydrophobicContact CB-CD2 4.04Å; F25-L32 HydrophobicContact CE1-CD1 3.88Å; F25-L32 HydrophobicContact CZ-CD1 3.89Å; F25-L32 HydrophobicContact CZ-CD2 4.46Å; I26-L32 HydrophobicContact CG1-CD1 4.49Å; N29-L32 HydrophobicContact CB-CD1 3.78Å; N29-L32 HydrophobicContact CB-CG 3.87Å; N29-L32 WeakPolarHBondContact O-CB 3.32Å; N29-L32 VanDerWaalsContact O-CG 3.23Å; N29-L32 WeakPolarHBondContact O-CG 3.49Å; N29-L32 PolarHBondContact O-N 3.1Å; P30-L32 PolarHBondContact O-N 2.97Å; L32-N34 VanDerWaalsContact C-N 3.34Å; L32-L35 WeakPolarHBondContact O-CD2 3.34Å
33F88Confident83.8Confident122 Ų12289.4 Ų89.454%0.53547%0.466SS..G310 helixtrans-88.51.5177.3-60.7-84.1000113.7F6 I26 P30 E31 L35F6-F33 HydrophobicContact CD2-CD1 4.29Å; F6-F33 HydrophobicContact CD2-CE1 4.16Å; F6-F33 HydrophobicContact CE2-CD1 4.33Å; F6-F33 AromaticContact CE2-CE1 3.86Å; F6-F33 HydrophobicContact CE2-CE1 3.86Å; F6-F33 HydrophobicContact CE2-CE2 4.32Å; F6-F33 AromaticContact CE2-CZ 3.86Å; F6-F33 HydrophobicContact CE2-CZ 3.86Å; I26-F33 HydrophobicContact CG2-CE2 3.88Å; I26-F33 HydrophobicContact CG2-CZ 3.72Å; P30-F33 PolarHBondContact O-N 3.03Å; P30-F33 VanDerWaalsContact O-N 3.14Å; E31-F33 PolarHBondContact O-N 3.32Å; E31-F33 VanDerWaalsContact O-N 3.16Å; F33-L35 PolarHBondContact O-N 3.38Å
34N83.3Confident83.9Confident114 Ų11486 Ų8661%0.6144%0.438SS*.  trans-75.375.5167.4-168.23.3000109.7N9 E31 L32 K36N9-N34 PolarHBondContact ND2-O 3.39Å; N9-N34 VanDerWaalsContact ND2-O 3.11Å; E31-N34 VanDerWaalsContact O-CB 3.26Å; E31-N34 WeakPolarHBondContact O-CB 3.4Å; E31-N34 PolarHBondContact O-N 3.36Å; L32-N34 VanDerWaalsContact C-N 3.34Å; N34-K36 PolarHBondContact O-N 3.13Å
35L81.3Confident84.1Confident77 Ų7780.9 Ų80.940%0.40342%0.415SS..  trans-81.1105.5-175.7-53.2-173.8000109.9P5 F6 L32 F33 P37P5-L35 HydrophobicContact CB-CB 4.33Å; P5-L35 HydrophobicContact CB-CD2 4.18Å; F6-L35 HydrophobicContact CB-CD2 3.89Å; L32-L35 WeakPolarHBondContact O-CD2 3.34Å; F33-L35 PolarHBondContact O-N 3.38Å; L35-P37 WeakPolarHBondContact O-CD 3.14Å
36K68.1Low84.2Confident168 Ų16880.3 Ų80.373%0.7341%0.412SS*.PPolyproline II helixtrans-66.3123.6172.2-69-172.1178.5-176.90109.9N34 T38N34-K36 PolarHBondContact O-N 3.13Å; K36-T38 PolarHBondContact O-N 3.36Å
37P66.1Low84.4Confident122 Ų12279.8 Ų79.879%0.79241%0.408SS*.PPolyproline II helixtrans-60.6130.3175.5-20.131.2000110.4L35 Q39L35-P37 WeakPolarHBondContact O-CD 3.14Å; P37-Q39 PolarHBondContact O-N 2.78Å
38T65.9Low84.8Confident114 Ų11473.2 Ų73.270%0.69937%0.373SS*.PPolyproline II helixtrans-67128172.451.70000109.8K36 N40K36-T38 PolarHBondContact O-N 3.36Å; T38-N40 PolarHBondContact O-N 3.31Å; T38-N40 VanDerWaalsContact O-N 3.07Å
39Q67.3Low85Confident150 Ų15068 Ų6870%0.70135%0.348SS*.  trans-68.2106.8177.8-67.9-170.1-100111.1P37 R41P37-Q39 PolarHBondContact O-N 2.78Å; Q39-R41 VanDerWaalsContact C-N 3.3Å; Q39-R41 HydrophobicContact CB-CG 4.47Å; Q39-R41 PolarHBondContact O-N 3.32Å
40N79.5Confident85.4Confident90 Ų9067.4 Ų67.448%0.48135%0.346SS..  trans-92.350.6-179-159.5-2.5000113T38 A42 Q43 K44T38-N40 PolarHBondContact O-N 3.31Å; T38-N40 VanDerWaalsContact O-N 3.07Å; N40-A42 VanDerWaalsContact C-N 3.35Å; N40-A42 PolarHBondContact O-N 3.49Å; N40-Q43 VanDerWaalsContact ND2-CB 3.32Å; N40-Q43 WeakPolarHBondContact ND2-CB 3.48Å; N40-Q43 PolarHBondContact O-N 3.32Å; N40-Q43 WeakPolarHBondContact OD1-CB 3.06Å; N40-Q43 PolarHBondContact OD1-N 2.92Å; N40-K44 WeakPolarHBondContact O-CG 3.18Å; N40-K44 PolarHBondContact O-N 3.29Å; N40-K44 VanDerWaalsContact O-N 3.16Å
41R84.8Confident85.7Confident65 Ų6565 Ų6525%0.24533%0.326CS..Hα-helixtrans-58.6-43.1-174.6-70.3-175.9-73.1175.8-0.7112.5Q39 K44 L45 L597 E598Q39-R41 VanDerWaalsContact C-N 3.3Å; Q39-R41 HydrophobicContact CB-CG 4.47Å; Q39-R41 PolarHBondContact O-N 3.32Å; R41-K44 PolarHBondContact O-N 2.99Å; R41-L45 PolarHBondContact O-N 3.26Å; R41-L597 HydrophobicContact CB-CD1 4.25Å; R41-E598 IonicContact CZ-OE1 2.99Å; R41-E598 IonicContact NH1-OE1 3.8Å; R41-E598 IonicContact NH1-OE2 3.77Å; R41-E598 PolarHBondContact NH1-OE2 2.79Å; R41-E598 IonicContact NH2-OE1 3.16Å; R41-E598 PolarHBondContact NH2-OE1 3.46Å; R41-E598 IonicContact NH2-OE2 3.75Å
42A87.9Confident86.1Confident21 Ų2160.7 Ų60.717%0.17431%0.306CS..Hα-helixtrans-64.3-45.8-179.400000112.7N40 K44 L45 L46 L603 L625N40-A42 VanDerWaalsContact C-N 3.35Å; N40-A42 PolarHBondContact O-N 3.49Å; A42-K44 VanDerWaalsContact C-N 3.3Å; A42-K44 PolarHBondContact O-N 3.12Å; A42-L45 PolarHBondContact O-N 2.89Å; A42-L46 WeakPolarHBondContact O-CG 3.17Å; A42-L46 PolarHBondContact O-N 3.21Å; A42-L603 HydrophobicContact CB-CD1 3.83Å; A42-L603 HydrophobicContact CB-CD2 4.34Å; A42-L625 HydrophobicContact CB-CD2 3.77Å
43Q89.9Confident86.4Confident55 Ų5562.5 Ų62.526%0.25732%0.315SS..Hα-helixtrans-63.9-37.2177.4-17271.913.700111.9N40 L46 H47 S631N40-Q43 VanDerWaalsContact ND2-CB 3.32Å; N40-Q43 WeakPolarHBondContact ND2-CB 3.48Å; N40-Q43 PolarHBondContact O-N 3.32Å; N40-Q43 WeakPolarHBondContact OD1-CB 3.06Å; N40-Q43 PolarHBondContact OD1-N 2.92Å; Q43-L46 PolarHBondContact O-N 3.44Å; Q43-H47 WeakPolarHBondContact O-CB 3.37Å; Q43-H47 PolarHBondContact O-N 3.12Å; Q43-S631 PolarHBondContact NE2-O 3.37Å
44K93.2Very high86.7Confident68 Ų6857.8 Ų57.830%0.29630%0.297SS..Hα-helixtrans-62.8-42.6176.2-72-175.6-176.2-163.70111.6N40 R41 A42 H47 Y48 S570 F572N40-K44 WeakPolarHBondContact O-CG 3.18Å; N40-K44 PolarHBondContact O-N 3.29Å; N40-K44 VanDerWaalsContact O-N 3.16Å; R41-K44 PolarHBondContact O-N 2.99Å; A42-K44 VanDerWaalsContact C-N 3.3Å; A42-K44 PolarHBondContact O-N 3.12Å; K44-H47 WeakPolarHBondContact O-CB 3.33Å; K44-H47 PolarHBondContact O-N 3.01Å; K44-Y48 PolarHBondContact O-N 3.45Å; K44-S570 WeakPolarHBondContact CD-O 2.97Å; K44-S570 WeakPolarHBondContact CE-O 3.32Å; K44-S570 PolarHBondContact NZ-O 3.39Å; K44-F572 CarbonylContact C-O 3.57Å; K44-F572 WeakPolarHBondContact CB-O 3.29Å; K44-F572 VanDerWaalsContact O-O 3.11Å
45L93.9Very high87.1Confident0 Ų054 Ų540%028%0.277CS..Hα-helixtrans-63.2-44.3173.4-76.2178.6000112.7R41 A42 H47 Y48 L49 F572 P574 L578 V595 L597 L603R41-L45 PolarHBondContact O-N 3.26Å; A42-L45 PolarHBondContact O-N 2.89Å; L45-H47 PolarHBondContact O-N 3.37Å; L45-Y48 WeakPolarHBondContact O-CB 3.49Å; L45-Y48 PolarHBondContact O-N 2.97Å; L45-Y48 VanDerWaalsContact O-N 3.12Å; L45-L49 WeakPolarHBondContact O-CG 3.44Å; L45-L49 PolarHBondContact O-N 2.97Å; L45-F572 PolarHBondContact N-O 3.46Å; L45-P574 WeakPolarHBondContact CD2-O 3.47Å; L45-L578 HydrophobicContact CD2-CD1 4.3Å; L45-L578 HydrophobicContact CD2-CD2 4.29Å; L45-L578 HydrophobicContact CD2-CG 4.23Å; L45-V595 HydrophobicContact CD1-CG1 4.15Å; L45-L597 HydrophobicContact CD1-CD2 3.58Å; L45-L603 HydrophobicContact CD1-CD1 4.16Å
46L95.2Very high87.6Confident0 Ų051.5 Ų51.50%027%0.269CS..Hα-helixtrans-59.7-37.1173.9-65.4-175.8000111.4A42 Q43 L49 G50 I605 F623 L625 R630 V632A42-L46 WeakPolarHBondContact O-CG 3.17Å; A42-L46 PolarHBondContact O-N 3.21Å; Q43-L46 PolarHBondContact O-N 3.44Å; L46-L49 HydrophobicContact CD2-CD1 4.44Å; L46-L49 PolarHBondContact O-N 2.67Å; L46-G50 PolarHBondContact O-N 3.2Å; L46-I605 HydrophobicContact CD2-CD1 4.02Å; L46-I605 HydrophobicContact CD2-CG1 4.22Å; L46-I605 HydrophobicContact CD2-CG2 3.71Å; L46-F623 HydrophobicContact CB-CD2 4.2Å; L46-F623 HydrophobicContact CB-CE2 4.41Å; L46-F623 HydrophobicContact CD1-CB 4.24Å; L46-F623 HydrophobicContact CD2-CB 3.95Å; L46-F623 HydrophobicContact CD2-CD1 4.02Å; L46-F623 HydrophobicContact CD2-CD2 4.11Å; L46-F623 HydrophobicContact CD2-CG 3.77Å; L46-L625 HydrophobicContact CD1-CB 4.36Å; L46-L625 HydrophobicContact CD1-CD2 4.23Å; L46-R630 HydrophobicContact CD1-CB 3.69Å; L46-R630 HydrophobicContact CD1-CG 4.03Å; L46-V632 HydrophobicContact CB-CG1 3.98Å
47H95.4Very high88.7Confident61 Ų6145.2 Ų45.228%0.28225%0.245SC..Hα-helixtrans-64.9-39.6175.6-176.7-150.2000111.8Q43 K44 L45 H51 N571 F572 V632Q43-H47 WeakPolarHBondContact O-CB 3.37Å; Q43-H47 PolarHBondContact O-N 3.12Å; K44-H47 WeakPolarHBondContact O-CB 3.33Å; K44-H47 PolarHBondContact O-N 3.01Å; L45-H47 PolarHBondContact O-N 3.37Å; H47-H51 WeakPolarHBondContact O-CB 3.45Å; H47-H51 PolarHBondContact O-N 2.91Å; H47-N571 PolarHBondContact ND1-O 3.25Å; H47-F572 AromaticContact CE1-CE1 3.88Å; H47-F572 AromaticContact ND1-CD1 3.95Å; H47-F572 AromaticContact ND1-CE1 3.8Å; H47-V632 HydrophobicContact CB-CG1 4.42Å
48Y96.4Very high89.8Confident0 Ų041.8 Ų41.80%022%0.222CC..Hα-helixtrans-64.8-50.7173.6-179.3-100.7000112K44 L45 G50 H51 V52 T58 F568 F572 V575 L578 F583K44-Y48 PolarHBondContact O-N 3.45Å; L45-Y48 WeakPolarHBondContact O-CB 3.49Å; L45-Y48 PolarHBondContact O-N 2.97Å; L45-Y48 VanDerWaalsContact O-N 3.12Å; Y48-G50 VanDerWaalsContact C-N 3.29Å; Y48-G50 PolarHBondContact O-N 2.83Å; Y48-H51 WeakPolarHBondContact O-CA 3.29Å; Y48-H51 VanDerWaalsContact O-CB 3.29Å; Y48-H51 WeakPolarHBondContact O-CB 3.49Å; Y48-H51 PolarHBondContact O-N 3.27Å; Y48-V52 HydrophobicContact CD1-CG2 4.2Å; Y48-V52 HydrophobicContact CE1-CG2 3.66Å; Y48-V52 HydrophobicContact CE2-CG2 4.05Å; Y48-V52 WeakPolarHBondContact O-CG2 3.12Å; Y48-V52 PolarHBondContact O-N 3.37Å; Y48-T58 HydrophobicContact CE2-CG2 4.12Å; Y48-F568 HydrophobicContact CD2-CE2 4.49Å; Y48-F568 AromaticContact CD2-CZ 3.81Å; Y48-F568 HydrophobicContact CD2-CZ 3.81Å; Y48-F568 HydrophobicContact CE2-CE2 4.25Å; Y48-F568 AromaticContact CE2-CZ 3.64Å; Y48-F568 HydrophobicContact CE2-CZ 3.64Å; Y48-F572 VanDerWaalsContact CA-CD1 3.44Å; Y48-F572 HydrophobicContact CD2-CB 4.07Å; Y48-F572 AromaticContact CD2-CD1 3.99Å; Y48-F572 HydrophobicContact CD2-CD1 3.99Å; Y48-F572 HydrophobicContact CD2-CD2 4.28Å; Y48-F572 HydrophobicContact CD2-CE1 4.49Å; Y48-F572 AromaticContact CD2-CG 3.86Å; Y48-F572 HydrophobicContact CD2-CG 3.86Å; Y48-F572 HydrophobicContact CG-CB 4.41Å; Y48-F572 HydrophobicContact CG-CD1 4.34Å; Y48-F572 HydrophobicContact CG-CG 4.45Å; Y48-V575 HydrophobicContact CD1-CG1 3.89Å; Y48-V575 HydrophobicContact CD2-CG1 3.87Å; Y48-V575 HydrophobicContact CE1-CG1 4.25Å; Y48-V575 HydrophobicContact CE2-CG1 4.22Å; Y48-V575 HydrophobicContact CG-CG1 3.69Å; Y48-L578 HydrophobicContact CD1-CD1 3.5Å; Y48-L578 HydrophobicContact CE1-CD1 3.73Å; Y48-F583 AromaticContact CE1-CD2 3.92Å; Y48-F583 HydrophobicContact CE1-CD2 3.92Å; Y48-F583 HydrophobicContact CE1-CE2 4.45Å; Y48-F583 AromaticContact CZ-CD2 3.75Å; Y48-F583 AromaticContact CZ-CE2 3.84Å; Y48-F583 VanDerWaalsContact OH-CD2 3.24Å; Y48-F583 WeakPolarHBondContact OH-CD2 3.48Å; Y48-F583 VanDerWaalsContact OH-CE2 3.22Å; Y48-F583 WeakPolarHBondContact OH-CE2 3.35Å; Y48-F583 PolarHBondContact OH-O 3.41Å
49L96.3Very high90.9Very high0 Ų036.4 Ų36.40%019%0.189CC..Hα-helixtrans-58.5-43.6178.7-67.3162.3000111L45 L46 H51 V52 M53 L578 L582 P587 F593 I605 F623L45-L49 WeakPolarHBondContact O-CG 3.44Å; L45-L49 PolarHBondContact O-N 2.97Å; L46-L49 HydrophobicContact CD2-CD1 4.44Å; L46-L49 PolarHBondContact O-N 2.67Å; L49-H51 VanDerWaalsContact C-N 3.34Å; L49-H51 PolarHBondContact O-N 2.71Å; L49-V52 PolarHBondContact O-N 3.08Å; L49-M53 VanDerWaalsContact O-CG 3.27Å; L49-M53 WeakPolarHBondContact O-CG 3.34Å; L49-M53 PolarHBondContact O-N 3.42Å; L49-L578 HydrophobicContact CD2-CD1 4.23Å; L49-L578 HydrophobicContact CD2-CD2 4.34Å; L49-L582 HydrophobicContact CD2-CB 4.39Å; L49-P587 HydrophobicContact CB-CG 4.45Å; L49-P587 HydrophobicContact CD2-CG 4.35Å; L49-F593 HydrophobicContact CD1-CE2 4.05Å; L49-F593 HydrophobicContact CD1-CZ 3.77Å; L49-F593 HydrophobicContact CD2-CZ 4.35Å; L49-I605 HydrophobicContact CD1-CD1 4.29Å; L49-F623 HydrophobicContact CB-CE1 4.2Å; L49-F623 HydrophobicContact CB-CZ 3.95Å
50G96.1Very high91.8Very high0 Ų033.2 Ų33.20%018%0.182CC..Hα-helixtrans-62.9-38.3173.500000112.9L46 Y48 M53 V54L46-G50 PolarHBondContact O-N 3.2Å; Y48-G50 VanDerWaalsContact C-N 3.29Å; Y48-G50 PolarHBondContact O-N 2.83Å; G50-M53 PolarHBondContact O-N 2.81Å; G50-V54 WeakPolarHBondContact O-CG2 3.41Å; G50-V54 PolarHBondContact O-N 3.42Å; G50-V54 VanDerWaalsContact O-N 3.13Å
51H95.7Very high92.1Very high39 Ų3932.4 Ų32.418%0.18118%0.176CC..Hα-helixtrans-59.5-48.3173.4-175.592.7000111.5H47 Y48 L49 M53 V54 N55 F572 V634H47-H51 WeakPolarHBondContact O-CB 3.45Å; H47-H51 PolarHBondContact O-N 2.91Å; Y48-H51 WeakPolarHBondContact O-CA 3.29Å; Y48-H51 VanDerWaalsContact O-CB 3.29Å; Y48-H51 WeakPolarHBondContact O-CB 3.49Å; Y48-H51 PolarHBondContact O-N 3.27Å; L49-H51 VanDerWaalsContact C-N 3.34Å; L49-H51 PolarHBondContact O-N 2.71Å; H51-M53 PolarHBondContact O-N 2.85Å; H51-V54 PolarHBondContact O-N 2.9Å; H51-N55 PolarHBondContact CE1-ND2 3.33Å; H51-N55 VanDerWaalsContact CE1-ND2 3.33Å; H51-N55 PolarHBondContact ND1-ND2 3.26Å; H51-N55 WeakPolarHBondContact O-CB 3.5Å; H51-N55 PolarHBondContact O-N 3.4Å; H51-F572 HydrophobicContact CB-CE1 3.89Å; H51-F572 HydrophobicContact CB-CZ 4.12Å; H51-F572 AromaticContact CG-CZ 3.97Å; H51-F572 AromaticContact ND1-CZ 3.98Å; H51-V634 HydrophobicContact CB-CG1 4.42Å
52V95.2Very high91.9Very high5 Ų531.6 Ų31.63%0.0318%0.18CC..Hα-helixtrans-63.5-41.7179.5179.60000111.3Y48 L49 V54 G56Y48-V52 HydrophobicContact CD1-CG2 4.2Å; Y48-V52 HydrophobicContact CE1-CG2 3.66Å; Y48-V52 HydrophobicContact CE2-CG2 4.05Å; Y48-V52 WeakPolarHBondContact O-CG2 3.12Å; Y48-V52 PolarHBondContact O-N 3.37Å; L49-V52 PolarHBondContact O-N 3.08Å; V52-V54 VanDerWaalsContact C-N 3.27Å; V52-V54 PolarHBondContact O-N 3.34Å; V52-G56 WeakPolarHBondContact CA-O 3.43Å; V52-G56 WeakPolarHBondContact O-CA 3.3Å; V52-G56 PolarHBondContact O-N 2.97Å
53M94.9Very high91.6Very high41 Ų4131.7 Ų31.720%0.20218%0.178CC..Hα-helixtrans-61-33176.1-70.1174.278.700113.4L49 G50 H51 P587 I589 A607 V621 F623L49-M53 VanDerWaalsContact O-CG 3.27Å; L49-M53 WeakPolarHBondContact O-CG 3.34Å; L49-M53 PolarHBondContact O-N 3.42Å; G50-M53 PolarHBondContact O-N 2.81Å; H51-M53 PolarHBondContact O-N 2.85Å; M53-P587 HydrophobicContact CG-CG 4.24Å; M53-P587 HydrophobicContact SD-CG 3.82Å; M53-I589 HydrophobicContact CE-CD1 3.55Å; M53-A607 HydrophobicContact CE-CB 4.09Å; M53-A607 HydrophobicContact SD-CB 4.29Å; M53-V621 HydrophobicContact CE-CG1 4.13Å; M53-V621 HydrophobicContact SD-CG1 3.75Å; M53-F623 HydrophobicContact SD-CE1 4.04Å; M53-F623 HydrophobicContact SD-CZ 3.79Å
54V94.1Very high91.3Very high24 Ų2440 Ų4015%0.14521%0.213CC..Hα-helixtrans-90.2-44.3-177.7173.10000112.7G50 H51 V52 L610 R619 V621 V634 D636G50-V54 WeakPolarHBondContact O-CG2 3.41Å; G50-V54 PolarHBondContact O-N 3.42Å; G50-V54 VanDerWaalsContact O-N 3.13Å; H51-V54 PolarHBondContact O-N 2.9Å; V52-V54 VanDerWaalsContact C-N 3.27Å; V52-V54 PolarHBondContact O-N 3.34Å; V54-L610 HydrophobicContact CG2-CD1 3.54Å; V54-R619 HydrophobicContact CG2-CB 4.15Å; V54-V621 HydrophobicContact CG2-CG2 4.04Å; V54-V634 HydrophobicContact CB-CG1 3.74Å; V54-V634 HydrophobicContact CG1-CG1 4.06Å; V54-V634 HydrophobicContact CG2-CB 4.06Å; V54-V634 HydrophobicContact CG2-CG1 3.84Å; V54-D636 HydrophobicContact CG1-CB 3.92Å
55N93.2Very high91Very high35 Ų3538.4 Ų38.419%0.18721%0.213CC..Hα-helixtrans-111.2-9.4-168-63.3-64.3000113.7H51 K635 T637H51-N55 PolarHBondContact CE1-ND2 3.33Å; H51-N55 VanDerWaalsContact CE1-ND2 3.33Å; H51-N55 PolarHBondContact ND1-ND2 3.26Å; H51-N55 WeakPolarHBondContact O-CB 3.5Å; H51-N55 PolarHBondContact O-N 3.4Å; N55-K635 PolarHBondContact ND2-O 3.25Å; N55-K635 PolarHBondContact OD1-O 3.36Å; N55-T637 WeakPolarHBondContact OD1-CB 3.33Å; N55-T637 PolarHBondContact OD1-N 3.48Å; N55-T637 PolarHBondContact OD1-OG1 3.46Å
56G91.8Very high90.8Very high24 Ų2445.8 Ų45.825%0.24725%0.245CC..  trans80.1-178.7-165.500000112.7V52V52-G56 WeakPolarHBondContact CA-O 3.43Å; V52-G56 WeakPolarHBondContact O-CA 3.3Å; V52-G56 PolarHBondContact O-N 2.97Å
57P90.3Very high90.7Very high36 Ų3646.5 Ų46.523%0.23425%0.25CC..  trans-64.7148.7-177.223.5-30.7000112.4T59 I61 L584P57-T59 VanDerWaalsContact C-N 3.27Å; P57-I61 HydrophobicContact CG-CD1 3.46Å; P57-I61 VanDerWaalsContact CG-CD1 3.46Å; P57-I61 HydrophobicContact CG-CG1 4.02Å; P57-L584 VanDerWaalsContact CB-O 3.25Å; P57-L584 WeakPolarHBondContact CB-O 3.41Å; P57-L584 WeakPolarHBondContact CD-O 3.49Å; P57-L584 WeakPolarHBondContact CG-O 3.36Å
58T88.3Confident90.6Very high49 Ų4945.3 Ų45.330%0.30125%0.249SC..SBendtrans-73.2-24.1173.854.20000112Y48 P60 F568Y48-T58 HydrophobicContact CE2-CG2 4.12Å; T58-P60 WeakPolarHBondContact O-CD 3.4Å; T58-F568 HydrophobicContact CG2-CE2 4.15Å
59T89.3Confident90.2Very high2 Ų249.6 Ų49.61%0.01228%0.278CS..SBendtrans-73.8123.6172.8-48.20000110.4P57 I61 F163 F393 F583P57-T59 VanDerWaalsContact C-N 3.27Å; T59-I61 PolarHBondContact O-N 3.17Å; T59-F163 HydrophobicContact CG2-CB 4.22Å; T59-F163 PolarHBondContact OG1-O 2.78Å; T59-F393 HydrophobicContact CG2-CE1 3.97Å; T59-F393 HydrophobicContact CG2-CZ 3.74Å; T59-F583 WeakPolarHBondContact OG1-CE1 3.28Å
60P87.1Confident89.9Confident83 Ų8353.5 Ų53.554%0.53930%0.302SS..PPolyproline II helixtrans-62.4122.4178.6-23.433.9000112T58 P62 F163 F393T58-P60 WeakPolarHBondContact O-CD 3.4Å; P60-P62 WeakPolarHBondContact O-CD 3.45Å; P60-F163 HydrophobicContact CG-CE1 4.4Å; P60-F393 WeakPolarHBondContact O-CE1 3.2Å
61I86.3Confident89.5Confident72 Ų7257.9 Ų57.937%0.36933%0.326SS..PPolyproline II helixtrans-90.4119.2178.4-69.4179.6000110.3P57 T59 V63 P392 F393P57-I61 HydrophobicContact CG-CD1 3.46Å; P57-I61 VanDerWaalsContact CG-CD1 3.46Å; P57-I61 HydrophobicContact CG-CG1 4.02Å; T59-I61 PolarHBondContact O-N 3.17Å; I61-V63 WeakPolarHBondContact CG2-O 3.29Å; I61-P392 HydrophobicContact CD1-CB 4.16Å; I61-P392 HydrophobicContact CG1-CB 4.17Å; I61-P392 HydrophobicContact CG2-CB 3.72Å; I61-F393 HydrophobicContact CG1-CE1 4.39Å; I61-F393 HydrophobicContact CG1-CZ 4.3Å
62P79.6Confident89.4Confident49 Ų4956.5 Ų56.532%0.31832%0.32SS..  trans-79.4-27.5-178.729.9-35.7000114.2P60 P392 F393 F421P60-P62 WeakPolarHBondContact O-CD 3.45Å; P62-P392 WeakPolarHBondContact CD-O 3.29Å; P62-P392 VanDerWaalsContact CG-O 3.29Å; P62-P392 WeakPolarHBondContact CG-O 3.29Å; P62-F393 VanDerWaalsContact CD-CD1 3.48Å; P62-F393 HydrophobicContact CG-CD1 4.02Å; P62-F421 HydrophobicContact CB-CB 4.15Å; P62-F421 HydrophobicContact CB-CD1 3.69Å; P62-F421 HydrophobicContact CB-CD2 3.74Å; P62-F421 HydrophobicContact CB-CE1 3.94Å; P62-F421 HydrophobicContact CB-CE2 3.97Å; P62-F421 HydrophobicContact CB-CG 3.6Å; P62-F421 HydrophobicContact CB-CZ 4.07Å; P62-F421 HydrophobicContact CG-CD1 4.28Å; P62-F421 HydrophobicContact CG-CD2 3.86Å; P62-F421 HydrophobicContact CG-CE1 4.06Å; P62-F421 HydrophobicContact CG-CE2 3.6Å; P62-F421 HydrophobicContact CG-CG 4.2Å; P62-F421 HydrophobicContact CG-CZ 3.72Å
63V81.6Confident89.4Confident23 Ų2361.9 Ų61.914%0.13935%0.353CS..SBendtrans-129.2151.9-176.2-61.20000112.6I61 A65 P392 A397 T398 F421I61-V63 WeakPolarHBondContact CG2-O 3.29Å; V63-A65 HydrophobicContact CG2-CB 4.2Å; V63-A65 PolarHBondContact O-N 3.06Å; V63-P392 VanDerWaalsContact CG2-C 3.48Å; V63-P392 WeakPolarHBondContact CG2-O 3.49Å; V63-A397 HydrophobicContact CB-CB 3.9Å; V63-A397 HydrophobicContact CG1-CB 3.74Å; V63-A397 HydrophobicContact CG2-CB 3.67Å; V63-T398 HydrophobicContact CG1-CG2 4.2Å; V63-F421 HydrophobicContact CG1-CE1 3.99Å
64K82.8Confident89.4Confident228 Ų22862.8 Ų62.899%0.99136%0.36SS*.SBendtrans-78.250.3179.9-61.5-176.4-178.2-179.90112.5
65A87.3Confident89.4Confident36 Ų3662.8 Ų62.830%0.29836%0.361SS..  trans-108.4157.2169.900000109.4V63 A391 P392V63-A65 HydrophobicContact CG2-CB 4.2Å; V63-A65 PolarHBondContact O-N 3.06Å; A65-A391 HydrophobicContact CB-CB 4.17Å; A65-A391 WeakPolarHBondContact CB-O 3.09Å; A65-P392 WeakPolarHBondContact O-CG 3.29Å
66K90.2Very high89.4Confident154 Ų15466.5 Ų66.567%0.6739%0.39SS*.  trans-112.3148.9177-70.4-165.4173.5-159.30110.4
67P92.9Very high89.5Confident16 Ų1668.2 Ų68.210%0.10440%0.395CS..  trans-53.9143.6168.9-2536000111.5L389 P392 L584 D585P67-L389 VanDerWaalsContact CB-O 3.31Å; P67-L389 WeakPolarHBondContact CB-O 3.31Å; P67-P392 HydrophobicContact CG-CG 3.92Å; P67-L584 HydrophobicContact CG-CB 3.77Å; P67-L584 HydrophobicContact CG-CD1 4.04Å; P67-D585 HydrophobicContact CG-CB 4.34Å
68S92.6Very high89.5Confident36 Ų3671.8 Ų71.825%0.25242%0.417SS..  trans-56.1145.6169.8-177.90000111T70 G388 L389S68-T70 VanDerWaalsContact C-N 3.31Å; S68-T70 PolarHBondContact OG-N 2.9Å; S68-T70 VanDerWaalsContact OG-N 3.17Å; S68-G388 WeakPolarHBondContact CB-O 3.5Å; S68-G388 PolarHBondContact N-O 3.4Å; S68-L389 WeakPolarHBondContact O-CD2 3.41Å
69S88.1Confident89.5Confident89 Ų8978.5 Ų78.562%0.62245%0.447SS*.SBendtrans-84.9-7.1171.7560000113.4
70T90.3Very high89.6Confident82 Ų8281.2 Ų81.250%0.50348%0.475SS..SBendtrans-91.6124.5-176.9-53.60000109.4S68 V385S68-T70 VanDerWaalsContact C-N 3.31Å; S68-T70 PolarHBondContact OG-N 2.9Å; S68-T70 VanDerWaalsContact OG-N 3.17Å; T70-V385 HydrophobicContact CG2-CG1 3.96Å
71D88.4Confident89.9Confident92 Ų9284.7 Ų84.749%0.49249%0.489SS..PPolyproline II helixtrans-76.3139.2172.4-72-39.5000110.6
72P93.7Very high90.3Very high10 Ų1082.7 Ų82.77%0.06548%0.481CS..PPolyproline II helixtrans-71.4137.5179.329.5-35.3000111.2Y382 V385 T386 L389P72-Y382 HydrophobicContact CB-CD2 3.86Å; P72-Y382 HydrophobicContact CB-CE2 3.67Å; P72-Y382 HydrophobicContact CG-CE2 3.88Å; P72-V385 HydrophobicContact CB-CB 4.12Å; P72-V385 HydrophobicContact CB-CG1 4.07Å; P72-T386 WeakPolarHBondContact CB-OG1 3.4Å; P72-T386 WeakPolarHBondContact CG-OG1 3.09Å; P72-L389 HydrophobicContact CG-CD1 4.36Å
73V94.1Very high91.1Very high118 Ų11883.2 Ų83.272%0.71548%0.484SS*.PPolyproline II helixtrans-85.2121.5176.3-179.60000108.8P75 Y382V73-P75 WeakPolarHBondContact O-CD 3.25Å; V73-Y382 WeakPolarHBondContact O-CD2 3.37Å
74V95.3Very high91.8Very high60 Ų6087.8 Ų87.836%0.36451%0.512SS..PPolyproline II helixtrans-78.4124.3176.1-177.50000108.8K134 Y382V74-K134 VanDerWaalsContact CG1-O 3.27Å; V74-K134 WeakPolarHBondContact CG1-O 3.32Å; V74-K134 HydrophobicContact CG2-CB 3.91Å; V74-K134 HydrophobicContact CG2-CD 4.46Å; V74-K134 HydrophobicContact CG2-CG 4.45Å; V74-Y382 HydrophobicContact CG2-CD2 4.37Å; V74-Y382 HydrophobicContact CG2-CE2 3.94Å
75P95.1Very high92.5Very high24 Ų2477.3 Ų77.316%0.15647%0.469CS..PPolyproline II helixtrans-62.4145.6176.5-20.231.7000111.7V73 I135 F138 D378V73-P75 WeakPolarHBondContact O-CD 3.25Å; P75-I135 HydrophobicContact CG-CD1 4.19Å; P75-F138 HydrophobicContact CB-CD2 3.61Å; P75-F138 HydrophobicContact CB-CE2 3.58Å; P75-F138 HydrophobicContact CB-CG 4.26Å; P75-F138 HydrophobicContact CB-CZ 4.21Å; P75-F138 HydrophobicContact CG-CD2 4.27Å; P75-F138 HydrophobicContact CG-CE2 4.31Å; P75-F138 HydrophobicContact CG-CG 4.45Å; P75-D378 HydrophobicContact CB-CB 4.25Å; P75-D378 HydrophobicContact CG-CB 4.22Å; P75-D378 WeakPolarHBondContact CG-O 3.43Å
76S92.6Very high93Very high113 Ų11376.8 Ų76.879%0.7946%0.46SS*.PPolyproline II helixtrans-66.1145.9-179.566.70000112.3
77V93.4Very high93.4Very high60 Ų6071.2 Ų71.236%0.36444%0.435SS..  trans-120.9148.8175.6-65.30000110.4P137 F138V77-P137 HydrophobicContact CG1-CB 4.45Å; V77-P137 HydrophobicContact CG2-CB 4.43Å; V77-F138 VanDerWaalsContact CG1-CA 3.45Å; V77-F138 HydrophobicContact CG1-CB 3.92Å; V77-F138 HydrophobicContact CG1-CD2 3.96Å; V77-F138 HydrophobicContact CG1-CG 4.43Å
78T89.7Confident93.6Very high112 Ų11273.2 Ų73.269%0.68745%0.445SS*.  trans-64.6137.4173.5-49.30000109.8H141T78-H141 PolarHBondContact O-CE1 3.43Å; T78-H141 VanDerWaalsContact O-CE1 3.29Å
79M88.7Confident93.9Very high190 Ų19072.8 Ų72.894%0.93644%0.441SS*.SBendtrans-66.9140.1173.7-66-160.3-156.700111
80G91.4Very high94.4Very high59 Ų5969 Ų6961%0.60841%0.413SS*.SBendtrans123.8-172.3177.800000111.7H141G80-H141 PolarHBondContact O-CE1 3.08Å; G80-H141 VanDerWaalsContact O-CE1 3.3Å; G80-H141 PolarHBondContact O-NE2 2.93Å
81D93.8Very high94.8Very high156 Ų15670 Ų7083%0.83442%0.415SS*.PPolyproline II helixtrans-75.4148.4176-64.2-39.7000110.8
82P95.2Very high95.2Very high29 Ų2973.9 Ų73.919%0.18842%0.422CS..PPolyproline II helixtrans-66.8157.4176.529.5-36.4000111.4S140 P180 N181P82-S140 WeakPolarHBondContact CB-OG 3.3Å; P82-S140 VanDerWaalsContact CG-OG 3.27Å; P82-S140 WeakPolarHBondContact CG-OG 3.22Å; P82-P180 HydrophobicContact CG-CG 3.7Å; P82-N181 HydrophobicContact CG-CB 4.47Å
83P96.2Very high95.5Very high60 Ų6076.8 Ų76.839%0.3944%0.437SS..PPolyproline II helixtrans-61155.2177.3-19.731.7000112.4G85 N181P83-G85 PolarHBondContact O-N 2.89Å; P83-N181 WeakPolarHBondContact O-CB 3.46Å; P83-N181 PolarHBondContact O-ND2 3.46Å
84V96.5Very high95.7Very high119 Ų11972.2 Ų72.272%0.72141%0.414SS*.PPolyproline II helixtrans-57.9134172.7179.10000109.7D88V84-D88 WeakPolarHBondContact CA-OD2 3.26Å; V84-D88 HydrophobicContact CG1-CB 3.73Å; V84-D88 WeakPolarHBondContact CG1-OD2 3.21Å
85G97.1Very high95.8Very high9 Ų970.3 Ų70.39%0.09340%0.403CS..  trans-127-174-178.900000113P83 R87 D88 S144 N181P83-G85 PolarHBondContact O-N 2.89Å; G85-R87 PolarHBondContact O-N 2.9Å; G85-D88 PolarHBondContact N-OD2 3.31Å; G85-D88 WeakPolarHBondContact O-CB 3.46Å; G85-D88 PolarHBondContact O-N 3.27Å; G85-D88 VanDerWaalsContact O-N 3.15Å; G85-S144 VanDerWaalsContact CA-O 3.24Å; G85-S144 WeakPolarHBondContact CA-O 3.37Å; G85-N181 CarbonylContact C-O 3.45Å; G85-N181 WeakPolarHBondContact CA-O 3.38Å
86F97.8Very high96Very high25 Ų2574.6 Ų74.611%0.1142%0.421CS..Hα-helixtrans-64.2-20-179-94.9-82.7000113.9D88 V89 L90 F98 V102 H105 L109 P183F86-D88 VanDerWaalsContact C-N 3.33Å; F86-V89 PolarHBondContact O-N 2.93Å; F86-L90 PolarHBondContact O-N 3.12Å; F86-F98 HydrophobicContact CB-CE2 4.06Å; F86-F98 HydrophobicContact CD1-CD2 4.39Å; F86-F98 AromaticContact CD1-CE2 3.95Å; F86-F98 HydrophobicContact CD1-CE2 3.95Å; F86-F98 HydrophobicContact CG-CE2 4.42Å; F86-V102 HydrophobicContact CD1-CG2 4.34Å; F86-V102 HydrophobicContact CE1-CG2 4.13Å; F86-H105 AromaticContact CZ-ND1 3.93Å; F86-L109 HydrophobicContact CD2-CD2 4.47Å; F86-L109 HydrophobicContact CE1-CD1 4.3Å; F86-L109 HydrophobicContact CE2-CD1 4.3Å; F86-L109 HydrophobicContact CE2-CD2 3.52Å; F86-L109 HydrophobicContact CZ-CD1 3.81Å; F86-L109 HydrophobicContact CZ-CD2 3.78Å; F86-L109 HydrophobicContact CZ-CG 4.46Å; F86-P183 HydrophobicContact CB-CG 3.89Å
87R98.3Very high96.3Very high37 Ų3770 Ų7014%0.1439%0.392CS..Hα-helixtrans-69.7-33.3175.7-164.7174.3173.4-101.2-6.4111.9G85 V89 L90 L91 R176 P180 N181 P183 D217G85-R87 PolarHBondContact O-N 2.9Å; R87-V89 VanDerWaalsContact C-N 3.26Å; R87-V89 PolarHBondContact O-N 3.45Å; R87-L90 WeakPolarHBondContact O-CB 3.18Å; R87-L90 PolarHBondContact O-N 2.96Å; R87-L90 VanDerWaalsContact O-N 3.16Å; R87-L91 HydrophobicContact CG-CD1 4.33Å; R87-L91 HydrophobicContact CG-CG 4.32Å; R87-L91 WeakPolarHBondContact O-CG 3.38Å; R87-L91 PolarHBondContact O-N 3.46Å; R87-R176 VanDerWaalsContact CD-NH1 3.28Å; R87-P180 WeakPolarHBondContact CD-O 3.35Å; R87-P180 PolarHBondContact NH1-O 3.38Å; R87-N181 WeakPolarHBondContact CB-O 3.38Å; R87-N181 PolarHBondContact N-O 3.25Å; R87-N181 VanDerWaalsContact N-O 3.14Å; R87-P183 HydrophobicContact CB-CG 4.03Å; R87-D217 VanDerWaalsContact CD-OD2 3.3Å; R87-D217 WeakPolarHBondContact CD-OD2 3.38Å; R87-D217 IonicContact NE-OD1 3.21Å; R87-D217 IonicContact NE-OD2 3.37Å; R87-D217 PolarHBondContact NE-OD2 3.02Å
88D98.2Very high96.5Very high58 Ų5867.1 Ų67.131%0.3137%0.374SS..Hα-helixtrans-63.8-36.7177.2-61.1-71000111.1V84 G85 F86 R92V84-D88 WeakPolarHBondContact CA-OD2 3.26Å; V84-D88 HydrophobicContact CG1-CB 3.73Å; V84-D88 WeakPolarHBondContact CG1-OD2 3.21Å; G85-D88 PolarHBondContact N-OD2 3.31Å; G85-D88 WeakPolarHBondContact O-CB 3.46Å; G85-D88 PolarHBondContact O-N 3.27Å; G85-D88 VanDerWaalsContact O-N 3.15Å; F86-D88 VanDerWaalsContact C-N 3.33Å; D88-R92 VanDerWaalsContact O-CB 3.27Å; D88-R92 WeakPolarHBondContact O-CB 3.18Å; D88-R92 PolarHBondContact O-N 3.37Å
89V98.1Very high96.9Very high27 Ų2762.2 Ų62.216%0.16435%0.345CS..Hα-helixtrans-63.8-46.5172.6-177.90000110.6F86 R87 L91 R92 D93 A101F86-V89 PolarHBondContact O-N 2.93Å; R87-V89 VanDerWaalsContact C-N 3.26Å; R87-V89 PolarHBondContact O-N 3.45Å; V89-L91 PolarHBondContact O-N 2.98Å; V89-R92 PolarHBondContact O-N 3.38Å; V89-D93 WeakPolarHBondContact O-CB 3.28Å; V89-D93 PolarHBondContact O-N 3.09Å; V89-A101 HydrophobicContact CG1-CB 3.75Å
90L98.4Very high97.4Very high8 Ų860.5 Ų60.54%0.04233%0.332CS..Hα-helixtrans-60.3-44.5177.9174.960.4000112.5F86 R87 R92 G94 P95 F98 D217 V244F86-L90 PolarHBondContact O-N 3.12Å; R87-L90 WeakPolarHBondContact O-CB 3.18Å; R87-L90 PolarHBondContact O-N 2.96Å; R87-L90 VanDerWaalsContact O-N 3.16Å; L90-R92 VanDerWaalsContact C-N 3.33Å; L90-R92 PolarHBondContact O-N 2.64Å; L90-G94 VanDerWaalsContact O-CA 3.24Å; L90-G94 WeakPolarHBondContact O-CA 3.38Å; L90-G94 PolarHBondContact O-N 3.35Å; L90-P95 HydrophobicContact CD1-CG 4.35Å; L90-F98 HydrophobicContact CB-CB 4.14Å; L90-F98 HydrophobicContact CB-CD2 3.96Å; L90-F98 HydrophobicContact CB-CG 4.21Å; L90-F98 HydrophobicContact CD1-CB 3.82Å; L90-F98 HydrophobicContact CD1-CG 4.22Å; L90-D217 HydrophobicContact CD2-CB 3.59Å; L90-V244 HydrophobicContact CD1-CG2 3.41Å; L90-V244 VanDerWaalsContact CD1-CG2 3.41Å; L90-V244 HydrophobicContact CD2-CG2 3.9Å; L90-V244 HydrophobicContact CG-CG2 4.32Å
91L98.2Very high97.8Very high103 Ų10359.2 Ų59.254%0.53932%0.316SS..Hα-helixtrans-68-33.8180-67.6176.2000112.4R87 V89R87-L91 HydrophobicContact CG-CD1 4.33Å; R87-L91 HydrophobicContact CG-CG 4.32Å; R87-L91 WeakPolarHBondContact O-CG 3.38Å; R87-L91 PolarHBondContact O-N 3.46Å; V89-L91 PolarHBondContact O-N 2.98Å
92R98.3Very high98Very high174 Ų17451.8 Ų51.866%0.65728%0.277SS*.Hα-helixtrans-79.3-45.5-179.6-172.7-172.264.2-140.2-5112.6D88 V89 L90D88-R92 VanDerWaalsContact O-CB 3.27Å; D88-R92 WeakPolarHBondContact O-CB 3.18Å; D88-R92 PolarHBondContact O-N 3.37Å; V89-R92 PolarHBondContact O-N 3.38Å; L90-R92 VanDerWaalsContact C-N 3.33Å; L90-R92 PolarHBondContact O-N 2.64Å
93D98.4Very high98.2Very high71 Ų7154.5 Ų54.538%0.3828%0.283SS..Hα-helixtrans-111.9-2.6-165.8-54.5-27.3000113.5V89V89-D93 WeakPolarHBondContact O-CB 3.28Å; V89-D93 PolarHBondContact O-N 3.09Å
94G98.6Very high98.3Very high22 Ų2254.9 Ų54.923%0.22729%0.291CS..Hα-helixtrans72.6-180-178.400000114.2L90 E96 G97 F98L90-G94 VanDerWaalsContact O-CA 3.24Å; L90-G94 WeakPolarHBondContact O-CA 3.38Å; L90-G94 PolarHBondContact O-N 3.35Å; G94-E96 PolarHBondContact O-N 2.92Å; G94-G97 PolarHBondContact O-N 2.67Å; G94-F98 WeakPolarHBondContact O-CB 3.31Å; G94-F98 PolarHBondContact O-N 3.34Å
95P98.6Very high98.3Very high21 Ų2152.1 Ų52.114%0.13627%0.27CS..Hα-helixtrans-56.6-41.4-176.7-30.138.7000115.2L90 F98 A99 V244 H281L90-P95 HydrophobicContact CD1-CG 4.35Å; P95-F98 WeakPolarHBondContact O-CB 3.25Å; P95-F98 PolarHBondContact O-N 3.28Å; P95-A99 PolarHBondContact O-N 2.87Å; P95-V244 HydrophobicContact CB-CG2 4.08Å; P95-V244 HydrophobicContact CG-CG2 4.43Å; P95-H281 WeakPolarHBondContact CB-NE2 3.14Å
96E98.3Very high98.3Very high113 Ų11359.6 Ų59.653%0.52830%0.303SS..Hα-helixtrans-70.8-38.3179.3-62.881.8173.400111.9G94 A99 K100 H281G94-E96 PolarHBondContact O-N 2.92Å; E96-A99 PolarHBondContact O-N 2.93Å; E96-K100 WeakPolarHBondContact O-CG 3.3Å; E96-K100 PolarHBondContact O-N 3.39Å; E96-K100 VanDerWaalsContact O-N 3.08Å; E96-H281 IonicContact OE1-NE2 3.39Å
97G98.5Very high98.3Very high17 Ų1759.4 Ų59.418%0.17531%0.308CS..Hα-helixtrans-64.1-42.4173.900000111.8G94 K100 A101G94-G97 PolarHBondContact O-N 2.67Å; G97-K100 PolarHBondContact O-N 2.78Å; G97-A101 PolarHBondContact O-N 3.09Å
98F98.8Very high98.3Very high0 Ų057.7 Ų57.70%030%0.301CS..Hα-helixtrans-58.6-51173173.8-102.9000112.2F86 L90 G94 P95 K100 A101 V102 F147 P183 I218 V244 I282F86-F98 HydrophobicContact CB-CE2 4.06Å; F86-F98 HydrophobicContact CD1-CD2 4.39Å; F86-F98 AromaticContact CD1-CE2 3.95Å; F86-F98 HydrophobicContact CD1-CE2 3.95Å; F86-F98 HydrophobicContact CG-CE2 4.42Å; L90-F98 HydrophobicContact CB-CB 4.14Å; L90-F98 HydrophobicContact CB-CD2 3.96Å; L90-F98 HydrophobicContact CB-CG 4.21Å; L90-F98 HydrophobicContact CD1-CB 3.82Å; L90-F98 HydrophobicContact CD1-CG 4.22Å; G94-F98 WeakPolarHBondContact O-CB 3.31Å; G94-F98 PolarHBondContact O-N 3.34Å; P95-F98 WeakPolarHBondContact O-CB 3.25Å; P95-F98 PolarHBondContact O-N 3.28Å; F98-K100 VanDerWaalsContact C-N 3.31Å; F98-K100 PolarHBondContact O-N 2.87Å; F98-A101 WeakPolarHBondContact O-CB 3.27Å; F98-A101 PolarHBondContact O-N 2.92Å; F98-A101 VanDerWaalsContact O-N 3.09Å; F98-V102 HydrophobicContact CD1-CG2 4.39Å; F98-V102 HydrophobicContact CD2-CG2 4.41Å; F98-V102 HydrophobicContact CE1-CG2 4.03Å; F98-V102 HydrophobicContact CE2-CG2 4.03Å; F98-V102 HydrophobicContact CZ-CG2 3.84Å; F98-V102 WeakPolarHBondContact O-CG2 3.29Å; F98-V102 PolarHBondContact O-N 3.49Å; F98-F147 HydrophobicContact CE1-CD2 4.42Å; F98-F147 AromaticContact CE1-CE2 3.61Å; F98-F147 HydrophobicContact CE1-CE2 3.61Å; F98-F147 HydrophobicContact CE1-CZ 4.15Å; F98-F147 AromaticContact CZ-CD2 3.81Å; F98-F147 HydrophobicContact CZ-CD2 3.81Å; F98-F147 AromaticContact CZ-CE2 3.43Å; F98-F147 HydrophobicContact CZ-CE2 3.43Å; F98-F147 VanDerWaalsContact CZ-CE2 3.43Å; F98-F147 HydrophobicContact CZ-CZ 4.16Å; F98-P183 HydrophobicContact CE2-CG 4.02Å; F98-P183 HydrophobicContact CZ-CG 4.36Å; F98-I218 HydrophobicContact CE1-CD1 3.78Å; F98-I218 HydrophobicContact CE1-CG1 4.49Å; F98-I218 HydrophobicContact CZ-CD1 3.73Å; F98-V244 HydrophobicContact CD1-CG1 3.98Å; F98-V244 HydrophobicContact CD1-CG2 3.81Å; F98-V244 HydrophobicContact CE1-CG1 4.15Å; F98-V244 HydrophobicContact CE1-CG2 4.26Å; F98-V244 HydrophobicContact CG-CG2 4.45Å; F98-I282 HydrophobicContact CD1-CD1 4.42Å; F98-I282 HydrophobicContact CE1-CD1 3.85Å
99A98.8Very high98.4Very high9 Ų955.1 Ų55.17%0.07429%0.287CS..Hα-helixtrans-58.9-41.2178.700000112.6P95 E96 A101 V102 R103 H281 P312P95-A99 PolarHBondContact O-N 2.87Å; E96-A99 PolarHBondContact O-N 2.93Å; A99-A101 PolarHBondContact O-N 3.32Å; A99-V102 PolarHBondContact O-N 2.82Å; A99-R103 PolarHBondContact O-N 2.62Å; A99-H281 HydrophobicContact CB-CB 4.15Å; A99-H281 WeakPolarHBondContact CB-O 3.28Å; A99-P312 HydrophobicContact CB-CG 4.1Å; A99-P312 WeakPolarHBondContact O-CG 3.48Å
100K98.7Very high98.4Very high153 Ų15353.9 Ų53.967%0.66528%0.28SS*.Hα-helixtrans-62.8-41.4174.5-73.2172-177173.50112.2E96 G97 F98 R103 A104E96-K100 WeakPolarHBondContact O-CG 3.3Å; E96-K100 PolarHBondContact O-N 3.39Å; E96-K100 VanDerWaalsContact O-N 3.08Å; G97-K100 PolarHBondContact O-N 2.78Å; F98-K100 VanDerWaalsContact C-N 3.31Å; F98-K100 PolarHBondContact O-N 2.87Å; K100-R103 PolarHBondContact O-N 3.41Å; K100-A104 VanDerWaalsContact O-CB 3.29Å; K100-A104 WeakPolarHBondContact O-CB 3.45Å; K100-A104 PolarHBondContact O-N 2.8Å
101A98.6Very high98.4Very high32 Ų3253.5 Ų53.526%0.26428%0.278SS..Hα-helixtrans-65.2-39.9177.700000112.1V89 G97 F98 A99 A104 H105V89-A101 HydrophobicContact CG1-CB 3.75Å; G97-A101 PolarHBondContact O-N 3.09Å; F98-A101 WeakPolarHBondContact O-CB 3.27Å; F98-A101 PolarHBondContact O-N 2.92Å; F98-A101 VanDerWaalsContact O-N 3.09Å; A99-A101 PolarHBondContact O-N 3.32Å; A101-A104 PolarHBondContact O-N 2.86Å; A101-H105 PolarHBondContact O-N 3Å; A101-H105 VanDerWaalsContact O-N 3.1Å
102V98.6Very high98.5Very high1 Ų148.6 Ų48.61%0.00625%0.252CS..Hα-helixtrans-60.8-48.7173.8172.60000110.4F86 F98 A99 A104 H105 L109 F147 P312 D337 V338F86-V102 HydrophobicContact CD1-CG2 4.34Å; F86-V102 HydrophobicContact CE1-CG2 4.13Å; F98-V102 HydrophobicContact CD1-CG2 4.39Å; F98-V102 HydrophobicContact CD2-CG2 4.41Å; F98-V102 HydrophobicContact CE1-CG2 4.03Å; F98-V102 HydrophobicContact CE2-CG2 4.03Å; F98-V102 HydrophobicContact CZ-CG2 3.84Å; F98-V102 WeakPolarHBondContact O-CG2 3.29Å; F98-V102 PolarHBondContact O-N 3.49Å; A99-V102 PolarHBondContact O-N 2.82Å; V102-A104 VanDerWaalsContact C-N 3.29Å; V102-A104 PolarHBondContact O-N 3.24Å; V102-H105 WeakPolarHBondContact O-CB 3.34Å; V102-H105 PolarHBondContact O-N 2.86Å; V102-L109 HydrophobicContact CB-CD1 4.48Å; V102-L109 HydrophobicContact CG1-CD1 3.99Å; V102-L109 HydrophobicContact CG2-CD1 4.49Å; V102-F147 HydrophobicContact CG1-CD2 4.16Å; V102-F147 HydrophobicContact CG1-CE2 4.17Å; V102-F147 HydrophobicContact CG2-CD2 3.77Å; V102-F147 HydrophobicContact CG2-CE2 3.78Å; V102-P312 HydrophobicContact CB-CG 4.35Å; V102-P312 HydrophobicContact CG1-CB 3.92Å; V102-P312 HydrophobicContact CG1-CG 4.26Å; V102-D337 HydrophobicContact CG1-CB 4.31Å; V102-V338 HydrophobicContact CG1-CG2 3.94Å
103R98.6Very high98.5Very high86 Ų8640.3 Ų40.333%0.32522%0.221SC..Hα-helixtrans-63.3-33.9179.2-175.964-15996.44.1113.5A99 K100 P309 P312 D337A99-R103 PolarHBondContact O-N 2.62Å; K100-R103 PolarHBondContact O-N 3.41Å; R103-P309 PolarHBondContact NE-O 2.84Å; R103-P312 HydrophobicContact CB-CG 4.14Å; R103-D337 IonicContact CZ-OD1 3.17Å; R103-D337 IonicContact NE-OD1 3.83Å; R103-D337 IonicContact NH1-OD1 2.91Å; R103-D337 PolarHBondContact NH1-OD1 3.07Å
104A98.3Very high98.5Very high67 Ų6737 Ų3755%0.55420%0.203SC*.Hα-helixtrans-81.1-15.1-179.200000113.7K100 A101 V102 Q106K100-A104 VanDerWaalsContact O-CB 3.29Å; K100-A104 WeakPolarHBondContact O-CB 3.45Å; K100-A104 PolarHBondContact O-N 2.8Å; A101-A104 PolarHBondContact O-N 2.86Å; V102-A104 VanDerWaalsContact C-N 3.29Å; V102-A104 PolarHBondContact O-N 3.24Å; A104-Q106 PolarHBondContact O-NE2 3.01Å
105H98.2Very high98.5Very high61 Ų6136 Ų3628%0.28219%0.193SC..  trans-58139.7-179.9-174.979.2000111.3F86 A101 V102 L109F86-H105 AromaticContact CZ-ND1 3.93Å; A101-H105 PolarHBondContact O-N 3Å; A101-H105 VanDerWaalsContact O-N 3.1Å; V102-H105 WeakPolarHBondContact O-CB 3.34Å; V102-H105 PolarHBondContact O-N 2.86Å; H105-L109 HydrophobicContact CB-CD1 4.04Å; H105-L109 HydrophobicContact CB-CG 4.42Å; H105-L109 VanDerWaalsContact CD2-CG 3.49Å; H105-L109 WeakPolarHBondContact CD2-CG 3.5Å; H105-L109 WeakPolarHBondContact NE2-CD2 3.44Å
106Q96.8Very high98.5Very high166 Ų16635 Ų3578%0.77619%0.186SC*.SBendtrans-99.8121.4175.9-62-59.3-61.800108.8A104A104-Q106 PolarHBondContact O-NE2 3.01Å
107G97.6Very high98.4Very high21 Ų2129.8 Ų29.822%0.21616%0.162CC..SBendtrans109.8178.8-172.200000111.9D368G107-D368 WeakPolarHBondContact CA-O 3.42Å
108L98.7Very high98.4Very high2 Ų229 Ų291%0.0115%0.154CC..  trans-94.6126176.1-18063.3000109.6L110 A332 V339 I358 T362 Y367 T369L108-L110 HydrophobicContact CD2-CD2 4.28Å; L108-L110 HydrophobicContact CG-CD2 4.26Å; L108-A332 HydrophobicContact CD1-CB 3.94Å; L108-A332 HydrophobicContact CD2-CB 3.82Å; L108-A332 HydrophobicContact CG-CB 4.41Å; L108-V339 HydrophobicContact CD1-CG1 4.2Å; L108-V339 HydrophobicContact CD1-CG2 4.24Å; L108-V339 HydrophobicContact CD2-CG2 3.74Å; L108-V339 HydrophobicContact CG-CG2 4.14Å; L108-I358 HydrophobicContact CD2-CG2 4.06Å; L108-T362 HydrophobicContact CD2-CG2 4.29Å; L108-Y367 WeakPolarHBondContact CB-O 3.46Å; L108-Y367 PolarHBondContact N-O 3.07Å; L108-T369 HydrophobicContact CB-CG2 4.41Å; L108-T369 WeakPolarHBondContact O-CA 3.19Å; L108-T369 WeakPolarHBondContact O-CG2 3.13Å
109L98.9Very high98.3Very high3 Ų329 Ų292%0.01615%0.154CC..EExtended strand (participates in β ladder)trans-85.4148.6171.2-68.1167.7000110.8F86 V102 H105 F147 D337 V338 V339F86-L109 HydrophobicContact CD2-CD2 4.47Å; F86-L109 HydrophobicContact CE1-CD1 4.3Å; F86-L109 HydrophobicContact CE2-CD1 4.3Å; F86-L109 HydrophobicContact CE2-CD2 3.52Å; F86-L109 HydrophobicContact CZ-CD1 3.81Å; F86-L109 HydrophobicContact CZ-CD2 3.78Å; F86-L109 HydrophobicContact CZ-CG 4.46Å; V102-L109 HydrophobicContact CB-CD1 4.48Å; V102-L109 HydrophobicContact CG1-CD1 3.99Å; V102-L109 HydrophobicContact CG2-CD1 4.49Å; H105-L109 HydrophobicContact CB-CD1 4.04Å; H105-L109 HydrophobicContact CB-CG 4.42Å; H105-L109 VanDerWaalsContact CD2-CG 3.49Å; H105-L109 WeakPolarHBondContact CD2-CG 3.5Å; H105-L109 WeakPolarHBondContact NE2-CD2 3.44Å; L109-F147 HydrophobicContact CB-CB 3.97Å; L109-F147 HydrophobicContact CD1-CB 4.45Å; L109-D337 PolarHBondContact N-O 2.8Å; L109-V338 HydrophobicContact CB-CG1 4.33Å; L109-V338 HydrophobicContact CB-CG2 4.1Å; L109-V338 HydrophobicContact CD1-CG2 4.46Å; L109-V338 WeakPolarHBondContact O-CA 3.31Å; L109-V339 PolarHBondContact O-N 3.13Å; L109-V339 VanDerWaalsContact O-N 3.14Å
110L98.9Very high98Very high2 Ų229.2 Ų29.21%0.0115%0.153CC..EExtended strand (participates in β ladder)trans-113.9141.8177.1-54.8-171.8000110.6L108 L146 F147 V339 V341 M355 I358 V359 T369 I371L108-L110 HydrophobicContact CD2-CD2 4.28Å; L108-L110 HydrophobicContact CG-CD2 4.26Å; L110-L146 HydrophobicContact CB-CD2 3.93Å; L110-L146 WeakPolarHBondContact O-CD2 3.39Å; L110-F147 PolarHBondContact O-N 3.09Å; L110-V339 HydrophobicContact CD2-CG2 3.65Å; L110-V341 HydrophobicContact CB-CG2 3.97Å; L110-V341 HydrophobicContact CD1-CG2 4.02Å; L110-V341 HydrophobicContact CD2-CG1 4.21Å; L110-V341 HydrophobicContact CG-CG2 4.44Å; L110-M355 HydrophobicContact CD1-CG 4.14Å; L110-I358 HydrophobicContact CD2-CG2 3.81Å; L110-V359 HydrophobicContact CD1-CG2 3.81Å; L110-T369 HydrophobicContact CD1-CG2 4.06Å; L110-T369 HydrophobicContact CD2-CG2 4.04Å; L110-T369 HydrophobicContact CG-CG2 3.97Å; L110-I371 HydrophobicContact CB-CD1 4.45Å; L110-I371 HydrophobicContact CD1-CD1 3.69Å; L110-I371 HydrophobicContact CG-CD1 4.21Å
111M98.8Very high97.8Very high0 Ų022 Ų220%012%0.122CC..EExtended strand (participates in β ladder)trans-105.8125.7162.5-175.7-170.890.500109.4T113 F147 S148 E150 Q185 H314 V338 V339 D340 V341M111-T113 HydrophobicContact CE-CG2 3.26Å; M111-F147 HydrophobicContact CB-CD1 4.17Å; M111-F147 HydrophobicContact CG-CD1 4.49Å; M111-S148 WeakPolarHBondContact CA-O 3.35Å; M111-S148 WeakPolarHBondContact CG-O 3.32Å; M111-S148 WeakPolarHBondContact CG-OG 3.26Å; M111-E150 HydrophobicContact CE-CB 3.56Å; M111-E150 HydrophobicContact CE-CG 4.24Å; M111-E150 HydrophobicContact SD-CB 3.97Å; M111-Q185 HydrophobicContact SD-CG 4.2Å; M111-Q185 PolarHBondContact SD-NE2 3.33Å; M111-Q185 VanDerWaalsContact SD-NE2 3.41Å; M111-H314 VanDerWaalsContact SD-CE1 3.59Å; M111-V338 HydrophobicContact CB-CG1 4.29Å; M111-V339 PolarHBondContact N-O 2.8Å; M111-D340 HydrophobicContact CE-CB 4.19Å; M111-D340 WeakPolarHBondContact CE-OD1 3.39Å; M111-D340 WeakPolarHBondContact CE-OD2 3.33Å; M111-V341 PolarHBondContact O-N 3.25Å
112D98.9Very high97.6Very high0 Ų020.4 Ų20.40%011%0.109CC..EExtended strand (participates in β ladder)trans-84.8122.7175.1-177.417.6000111T114 L146 S148 L149 E150 V341 M355 Y379D112-T114 WeakPolarHBondContact OD1-CB 3.18Å; D112-T114 PolarHBondContact OD1-N 2.8Å; D112-T114 PolarHBondContact OD1-OG1 3.19Å; D112-L146 HydrophobicContact CB-CD1 3.9Å; D112-L146 HydrophobicContact CB-CD2 4.44Å; D112-S148 PolarHBondContact N-O 2.99Å; D112-L149 HydrophobicContact CB-CD1 3.8Å; D112-E150 PolarHBondContact O-N 3.27Å; D112-V341 WeakPolarHBondContact CA-O 3.25Å; D112-M355 HydrophobicContact CB-CE 3.9Å; D112-Y379 WeakPolarHBondContact OD2-CE1 3.33Å; D112-Y379 PolarHBondContact OD2-OH 3.48Å
113T98.8Very high97.4Very high0 Ų020.4 Ų20.40%011%0.109CC..  trans-98.32175.661.50000113.8M111 F115 R116 D117 A118 D340 V341 Q352M111-T113 HydrophobicContact CE-CG2 3.26Å; T113-F115 PolarHBondContact O-N 3.08Å; T113-R116 CarbonylContact O-C 3.51Å; T113-R116 PolarHBondContact O-N 3.5Å; T113-D117 HydrophobicContact CG2-CB 4.27Å; T113-D117 PolarHBondContact O-N 3.17Å; T113-D117 VanDerWaalsContact O-N 3.09Å; T113-A118 PolarHBondContact O-N 3.32Å; T113-A118 VanDerWaalsContact O-N 3.16Å; T113-D340 HydrophobicContact CG2-CB 4.06Å; T113-V341 PolarHBondContact N-O 2.88Å; T113-V341 PolarHBondContact OG1-O 3.34Å; T113-Q352 HydrophobicContact CG2-CG 3.86Å; T113-Q352 VanDerWaalsContact OG1-CD 3.32Å; T113-Q352 WeakPolarHBondContact OG1-CG 3.38Å; T113-Q352 PolarHBondContact OG1-OE1 3.11Å
114T98.8Very high97.1Very high0 Ų016.5 Ų16.50%010%0.095CC..THydrogen-bonded Turntrans-56-32-174.1-57.20000112.4D112 H119 V343 M346 Y379 W383D112-T114 WeakPolarHBondContact OD1-CB 3.18Å; D112-T114 PolarHBondContact OD1-N 2.8Å; D112-T114 PolarHBondContact OD1-OG1 3.19Å; T114-H119 PolarHBondContact O-CD2 2.86Å; T114-V343 HydrophobicContact CG2-CG1 3.64Å; T114-V343 PolarHBondContact OG1-N 2.89Å; T114-M346 HydrophobicContact CG2-CB 4.13Å; T114-M346 HydrophobicContact CG2-CG 4.08Å; T114-Y379 WeakPolarHBondContact CB-OH 3.39Å; T114-W383 HydrophobicContact CG2-CD2 3.87Å; T114-W383 HydrophobicContact CG2-CG 4.22Å; T114-W383 HydrophobicContact CG2-CH2 4.43Å; T114-W383 HydrophobicContact CG2-CZ2 3.72Å
115F98.6Very high96.9Very high1 Ų113.6 Ų13.60%0.0047%0.071CC..THydrogen-bonded Turntrans-83.2-8.6-178.3-80.250.1000114T113 H119 L132 I135 V139 L149 E150 N151 L175 I179 Y379 W383T113-F115 PolarHBondContact O-N 3.08Å; F115-H119 VanDerWaalsContact C-NE2 3.34Å; F115-H119 PolarHBondContact O-NE2 2.93Å; F115-L132 HydrophobicContact CB-CD2 4.07Å; F115-L132 HydrophobicContact CD1-CD2 4.01Å; F115-L132 HydrophobicContact CD2-CB 4.11Å; F115-L132 HydrophobicContact CD2-CD2 3.62Å; F115-L132 HydrophobicContact CD2-CG 4.31Å; F115-L132 HydrophobicContact CE1-CD2 4.35Å; F115-L132 HydrophobicContact CE2-CB 3.93Å; F115-L132 HydrophobicContact CE2-CD2 4.01Å; F115-L132 HydrophobicContact CG-CD2 3.62Å; F115-L132 HydrophobicContact CZ-CD2 4.36Å; F115-I135 HydrophobicContact CE1-CG2 4.04Å; F115-I135 HydrophobicContact CZ-CG2 3.75Å; F115-V139 HydrophobicContact CE1-CG2 4.18Å; F115-V139 HydrophobicContact CZ-CG2 4.23Å; F115-L149 HydrophobicContact CB-CD1 4.13Å; F115-L149 HydrophobicContact CB-CG 4.37Å; F115-L149 HydrophobicContact CD1-CD1 3.85Å; F115-L149 HydrophobicContact CD1-CD2 4.39Å; F115-L149 HydrophobicContact CD2-CD2 3.88Å; F115-L149 HydrophobicContact CE1-CD1 4.44Å; F115-L149 HydrophobicContact CE2-CD2 4.09Å; F115-L149 HydrophobicContact CG-CD1 3.95Å; F115-L149 HydrophobicContact CG-CD2 4.04Å; F115-L149 HydrophobicContact CG-CG 4.27Å; F115-L149 HydrophobicContact CZ-CD2 4.45Å; F115-E150 CarbonylContact C-O 3.57Å; F115-E150 WeakPolarHBondContact CB-O 3.48Å; F115-N151 HydrophobicContact CB-CB 3.65Å; F115-N151 HydrophobicContact CD2-CB 4.26Å; F115-N151 HydrophobicContact CG-CB 4.41Å; F115-L175 HydrophobicContact CD2-CD1 4.11Å; F115-L175 HydrophobicContact CE2-CD1 4.46Å; F115-L175 HydrophobicContact CE2-CD2 4.06Å; F115-I179 HydrophobicContact CE2-CD1 4.17Å; F115-I179 HydrophobicContact CZ-CD1 4.45Å; F115-Y379 VanDerWaalsContact CE1-OH 3.28Å; F115-Y379 WeakPolarHBondContact CE1-OH 3.3Å; F115-W383 HydrophobicContact CD1-CZ2 4.36Å; F115-W383 HydrophobicContact CE1-CZ2 4.13Å
116R97.8Very high96.8Very high0 Ų011.8 Ų11.80%06%0.061CC..THydrogen-bonded Turntrans-139-80.1-178.5-156.2-76.7-67.9166.94.5113.1T113 A118 H119 Q120 E150 D154 A156T113-R116 CarbonylContact O-C 3.51Å; T113-R116 PolarHBondContact O-N 3.5Å; R116-A118 PolarHBondContact O-N 3.02Å; R116-H119 WeakPolarHBondContact CA-NE2 3.35Å; R116-H119 PolarHBondContact O-CD2 2.88Å; R116-H119 VanDerWaalsContact O-CD2 3.26Å; R116-H119 PolarHBondContact O-NE2 3.4Å; R116-Q120 WeakPolarHBondContact O-CB 3.37Å; R116-Q120 PolarHBondContact O-N 2.75Å; R116-Q120 VanDerWaalsContact O-N 3.11Å; R116-E150 HydrophobicContact CB-CG 4.07Å; R116-E150 VanDerWaalsContact CB-O 3.25Å; R116-E150 WeakPolarHBondContact CB-O 3.43Å; R116-E150 HydrophobicContact CG-CG 4.43Å; R116-E150 IonicContact CZ-OE1 3.78Å; R116-E150 IonicContact CZ-OE2 2.7Å; R116-E150 PolarHBondContact N-O 3.12Å; R116-E150 VanDerWaalsContact NE-CD 3.29Å; R116-E150 IonicContact NE-OE1 2.67Å; R116-E150 IonicContact NE-OE2 2.76Å; R116-E150 PolarHBondContact NE-OE2 2.89Å; R116-E150 IonicContact NH2-OE1 2.72Å; R116-E150 PolarHBondContact NH2-OE1 2.86Å; R116-E150 IonicContact NH2-OE2 3.63Å; R116-E150 PolarHBondContact NH2-OE2 3Å; R116-D154 IonicContact NH1-OD2 3.58Å; R116-A156 HydrophobicContact CG-CB 4.31Å
117D97.5Very high96.8Very high4 Ų43.9 Ų3.92%0.0212%0.024CC..Hα-helixtrans-72-30.6-167.1-155.846.3000114.1T113 Q120 S121 E150 H316 H318 Q352T113-D117 HydrophobicContact CG2-CB 4.27Å; T113-D117 PolarHBondContact O-N 3.17Å; T113-D117 VanDerWaalsContact O-N 3.09Å; D117-Q120 WeakPolarHBondContact O-CB 2.99Å; D117-Q120 PolarHBondContact O-N 2.89Å; D117-S121 WeakPolarHBondContact O-CB 3.26Å; D117-S121 PolarHBondContact O-N 2.64Å; D117-S121 PolarHBondContact O-OG 3.45Å; D117-E150 WeakPolarHBondContact CB-OE2 3.26Å; D117-H316 IonicContact OD2-CE1 2.7Å; D117-H316 PolarHBondContact OD2-CE1 3.34Å; D117-H316 IonicContact OD2-NE2 2.93Å; D117-H318 IonicContact OD2-CE1 3.27Å; D117-H318 PolarHBondContact OD2-CE1 3.36Å; D117-H318 IonicContact OD2-NE2 3.58Å; D117-H318 PolarHBondContact OD2-NE2 3.11Å; D117-Q352 PolarHBondContact OD2-NE2 3.3Å
118A97.5Very high96.8Very high0 Ų03 Ų30%01%0.014CC..Hα-helixtrans-62.2-53-179.500000111.4T113 R116 Q120 S121 L122 A342 M346 S351T113-A118 PolarHBondContact O-N 3.32Å; T113-A118 VanDerWaalsContact O-N 3.16Å; R116-A118 PolarHBondContact O-N 3.02Å; A118-Q120 VanDerWaalsContact C-N 3.34Å; A118-S121 PolarHBondContact O-N 2.94Å; A118-L122 WeakPolarHBondContact O-CB 3.41Å; A118-L122 WeakPolarHBondContact O-CG 3.44Å; A118-L122 PolarHBondContact O-N 3.49Å; A118-A342 HydrophobicContact CB-CB 3.9Å; A118-M346 HydrophobicContact CB-CB 4.29Å; A118-S351 VanDerWaalsContact CA-OG 3.3Å; A118-S351 WeakPolarHBondContact CA-OG 3.3Å; A118-S351 WeakPolarHBondContact CB-OG 3.33Å
119H96.2Very high96.8Very high0 Ų03.1 Ų3.10%02%0.015CC..Hα-helixtrans-74.9-24.2177.772.687.2000112.9T114 F115 R116 S121 L123 A124 T125 V127 M346T114-H119 PolarHBondContact O-CD2 2.86Å; F115-H119 VanDerWaalsContact C-NE2 3.34Å; F115-H119 PolarHBondContact O-NE2 2.93Å; R116-H119 WeakPolarHBondContact CA-NE2 3.35Å; R116-H119 PolarHBondContact O-CD2 2.88Å; R116-H119 VanDerWaalsContact O-CD2 3.26Å; R116-H119 PolarHBondContact O-NE2 3.4Å; H119-S121 PolarHBondContact O-N 3.49Å; H119-L123 HydrophobicContact CB-CB 4.27Å; H119-L123 HydrophobicContact CB-CD1 4.2Å; H119-L123 HydrophobicContact CB-CG 4.46Å; H119-L123 CarbonylContact O-C 3.58Å; H119-L123 VanDerWaalsContact O-C 3.25Å; H119-L123 VanDerWaalsContact O-CA 3.3Å; H119-L123 WeakPolarHBondContact O-CA 3.32Å; H119-L123 WeakPolarHBondContact O-CB 3.36Å; H119-L123 PolarHBondContact O-N 2.99Å; H119-A124 PolarHBondContact O-N 2.62Å; H119-T125 VanDerWaalsContact ND1-CA 3.28Å; H119-T125 WeakPolarHBondContact ND1-CA 3.27Å; H119-T125 PolarHBondContact O-N 2.84Å; H119-V127 HydrophobicContact CB-CB 3.95Å; H119-V127 HydrophobicContact CB-CG2 3.36Å; H119-M346 HydrophobicContact CB-CE 3.78Å
120Q94.1Very high96.7Very high15 Ų154.6 Ų4.67%0.072%0.022CC..Hα-helixtrans-58.6-41.2167.3175.3168.2-2700111.4R116 D117 A118 T125 D154R116-Q120 WeakPolarHBondContact O-CB 3.37Å; R116-Q120 PolarHBondContact O-N 2.75Å; R116-Q120 VanDerWaalsContact O-N 3.11Å; D117-Q120 WeakPolarHBondContact O-CB 2.99Å; D117-Q120 PolarHBondContact O-N 2.89Å; A118-Q120 VanDerWaalsContact C-N 3.34Å; Q120-T125 WeakPolarHBondContact CA-OG1 3.16Å; Q120-T125 HydrophobicContact CB-CG2 4.28Å; Q120-T125 WeakPolarHBondContact CG-OG1 3.47Å; Q120-D154 PolarHBondContact NE2-OD2 3.24Å
121S93.6Very high96.6Very high0 Ų04.6 Ų4.60%02%0.022CC..Hα-helixtrans-79.9-42.7-178.4-58.50000113.4D117 A118 H119 H318 T350 T417D117-S121 WeakPolarHBondContact O-CB 3.26Å; D117-S121 PolarHBondContact O-N 2.64Å; D117-S121 PolarHBondContact O-OG 3.45Å; A118-S121 PolarHBondContact O-N 2.94Å; H119-S121 PolarHBondContact O-N 3.49Å; S121-H318 PolarHBondContact OG-CE1 2.83Å; S121-T350 WeakPolarHBondContact CB-O 3.38Å; S121-T350 PolarHBondContact O-OG1 3.49Å; S121-T350 PolarHBondContact OG-O 3.07Å; S121-T417 PolarHBondContact O-OG1 3.04Å
122L94.2Very high96.6Very high0 Ų04.6 Ų4.60%02%0.022CC..Hα-helixtrans-90.7-36.8-173-64.3176.7000113.8A118 M346 M349 C395A118-L122 WeakPolarHBondContact O-CB 3.41Å; A118-L122 WeakPolarHBondContact O-CG 3.44Å; A118-L122 PolarHBondContact O-N 3.49Å; L122-M346 HydrophobicContact CD1-CB 4.48Å; L122-M346 WeakPolarHBondContact CD1-O 3.4Å; L122-M349 HydrophobicContact CD2-CE 3.68Å; L122-C395 PolarHBondContact O-N 2.8Å
123L94.3Very high96.5Very high0 Ų07.9 Ų7.90%04%0.036CC..SBendtrans-125.122.7-165-54179.4000112.3H119 T125 R126 V127 M346 R387 Y390 D394H119-L123 HydrophobicContact CB-CB 4.27Å; H119-L123 HydrophobicContact CB-CD1 4.2Å; H119-L123 HydrophobicContact CB-CG 4.46Å; H119-L123 CarbonylContact O-C 3.58Å; H119-L123 VanDerWaalsContact O-C 3.25Å; H119-L123 VanDerWaalsContact O-CA 3.3Å; H119-L123 WeakPolarHBondContact O-CA 3.32Å; H119-L123 WeakPolarHBondContact O-CB 3.36Å; H119-L123 PolarHBondContact O-N 2.99Å; L123-T125 PolarHBondContact O-N 2.61Å; L123-T125 VanDerWaalsContact O-N 3.11Å; L123-R126 VanDerWaalsContact O-CB 3.29Å; L123-R126 WeakPolarHBondContact O-CB 3.3Å; L123-R126 VanDerWaalsContact O-CG 3.31Å; L123-R126 WeakPolarHBondContact O-CG 3.24Å; L123-R126 PolarHBondContact O-N 3.02Å; L123-V127 HydrophobicContact CD1-CG2 3.67Å; L123-M346 HydrophobicContact CD1-CE 3.73Å; L123-M346 HydrophobicContact CD1-SD 4.27Å; L123-M346 HydrophobicContact CG-CE 4.44Å; L123-R387 HydrophobicContact CD1-CG 4.5Å; L123-R387 HydrophobicContact CD2-CG 4.25Å; L123-Y390 HydrophobicContact CD1-CD2 4.18Å; L123-Y390 HydrophobicContact CD1-CG 4.02Å; L123-D394 HydrophobicContact CD2-CB 3.92Å
124A91.9Very high96.4Very high5 Ų511.3 Ų11.34%0.0415%0.051CC..THydrogen-bonded Turntrans48.639.4-176.600000113.4H119 R126 F421H119-A124 PolarHBondContact O-N 2.62Å; A124-R126 PolarHBondContact O-N 3.19Å; A124-R126 PolarHBondContact O-NH1 3.26Å; A124-F421 HydrophobicContact CB-CE2 4.04Å
125T94.6Very high96.4Very high6 Ų611.3 Ų11.34%0.0375%0.051CC..THydrogen-bonded Turntrans64.721.7178.1-31.90000114H119 Q120 L123 V127 A155 A156 V159H119-T125 VanDerWaalsContact ND1-CA 3.28Å; H119-T125 WeakPolarHBondContact ND1-CA 3.27Å; H119-T125 PolarHBondContact O-N 2.84Å; Q120-T125 WeakPolarHBondContact CA-OG1 3.16Å; Q120-T125 HydrophobicContact CB-CG2 4.28Å; Q120-T125 WeakPolarHBondContact CG-OG1 3.47Å; L123-T125 PolarHBondContact O-N 2.61Å; L123-T125 VanDerWaalsContact O-N 3.11Å; T125-V127 PolarHBondContact O-N 3.12Å; T125-A155 HydrophobicContact CG2-CB 4.49Å; T125-A156 HydrophobicContact CG2-CB 4.11Å; T125-V159 HydrophobicContact CG2-CB 4.15Å; T125-V159 HydrophobicContact CG2-CG1 4.23Å; T125-V159 HydrophobicContact CG2-CG2 4.28Å; T125-V159 WeakPolarHBondContact O-CG1 3.39Å
126R95.4Very high96.4Very high23 Ų2311.2 Ų11.29%0.0875%0.051CC..  trans-85.8-0.7-170.9-65.6-63.5-175.6-94.85115.4L123 A124 R128 V159 F163 L164 Y390 F393L123-R126 VanDerWaalsContact O-CB 3.29Å; L123-R126 WeakPolarHBondContact O-CB 3.3Å; L123-R126 VanDerWaalsContact O-CG 3.31Å; L123-R126 WeakPolarHBondContact O-CG 3.24Å; L123-R126 PolarHBondContact O-N 3.02Å; A124-R126 PolarHBondContact O-N 3.19Å; A124-R126 PolarHBondContact O-NH1 3.26Å; R126-R128 PolarHBondContact O-N 2.92Å; R126-V159 VanDerWaalsContact NH1-CG1 3.27Å; R126-F163 VanDerWaalsContact CZ-CG 3.45Å; R126-F163 VanDerWaalsContact NH1-CD2 3.34Å; R126-F163 VanDerWaalsContact NH2-CE2 3.3Å; R126-L164 HydrophobicContact CB-CD2 4.42Å; R126-L164 WeakPolarHBondContact O-CD2 3.16Å; R126-Y390 HydrophobicContact CB-CD1 4.19Å; R126-Y390 HydrophobicContact CB-CE1 4.5Å; R126-Y390 WeakPolarHBondContact O-CE1 3.47Å; R126-F393 HydrophobicContact CB-CB 4.47Å; R126-F393 HydrophobicContact CB-CD2 3.81Å; R126-F393 HydrophobicContact CB-CE2 4.14Å; R126-F393 HydrophobicContact CB-CG 4.03Å; R126-F393 HydrophobicContact CG-CB 4.24Å; R126-F393 HydrophobicContact CG-CD1 3.75Å; R126-F393 HydrophobicContact CG-CD2 3.91Å; R126-F393 HydrophobicContact CG-CE1 4.03Å; R126-F393 HydrophobicContact CG-CE2 4.17Å; R126-F393 HydrophobicContact CG-CG 3.69Å; R126-F393 HydrophobicContact CG-CZ 4.23Å
127V97.9Very high96.4Very high0 Ų013.1 Ų13.10%06%0.063CC..  trans-65.6127.8179.61740000111H119 L123 T125 L132 L164 R171 W383 Y390H119-V127 HydrophobicContact CB-CB 3.95Å; H119-V127 HydrophobicContact CB-CG2 3.36Å; L123-V127 HydrophobicContact CD1-CG2 3.67Å; T125-V127 PolarHBondContact O-N 3.12Å; V127-L132 HydrophobicContact CG1-CD1 4.3Å; V127-L132 HydrophobicContact CG1-CD2 3.77Å; V127-L132 HydrophobicContact CG1-CG 3.82Å; V127-L164 WeakPolarHBondContact O-CD1 3.39Å; V127-R171 PolarHBondContact O-NH1 3.25Å; V127-R171 PolarHBondContact O-NH2 2.83Å; V127-W383 HydrophobicContact CG1-CH2 3.81Å; V127-W383 HydrophobicContact CG1-CZ3 3.99Å; V127-W383 HydrophobicContact CG2-CZ3 4.33Å; V127-Y390 HydrophobicContact CG2-CD2 4.24Å; V127-Y390 HydrophobicContact CG2-CE1 4.44Å; V127-Y390 HydrophobicContact CG2-CE2 4.04Å
128R98Very high96.4Very high1 Ų113 Ų130%0.0046%0.063CC..  trans-89.4155.4-172.5-68.9-177.560.3-120.85.1112.5R126 H130 D131 L132 L164 E166 Y390 V575 D576 L578 T580R126-R128 PolarHBondContact O-N 2.92Å; R128-H130 PolarHBondContact O-N 3.11Å; R128-D131 PolarHBondContact O-N 3.13Å; R128-L132 WeakPolarHBondContact O-CG 3.35Å; R128-L132 PolarHBondContact O-N 3.06Å; R128-L164 HydrophobicContact CG-CD1 4.17Å; R128-L164 HydrophobicContact CG-CD2 4.01Å; R128-L164 HydrophobicContact CG-CG 4.5Å; R128-E166 WeakPolarHBondContact CB-OE1 3.49Å; R128-E166 IonicContact CZ-OE1 3.9Å; R128-E166 IonicContact NE-OE1 3.94Å; R128-E166 PolarHBondContact NE-OE1 2.85Å; R128-E166 IonicContact NH2-OE1 3.21Å; R128-E166 PolarHBondContact NH2-OE1 3.17Å; R128-Y390 WeakPolarHBondContact CB-OH 3.08Å; R128-Y390 HydrophobicContact CG-CE1 4.48Å; R128-Y390 PolarHBondContact N-OH 3.39Å; R128-V575 PolarHBondContact NH2-O 3.16Å; R128-D576 PolarHBondContact NH2-O 2.89Å; R128-L578 VanDerWaalsContact CZ-O 3.31Å; R128-L578 PolarHBondContact NH1-O 2.94Å; R128-L578 PolarHBondContact NH2-O 3.12Å; R128-T580 VanDerWaalsContact NH1-CA 3.26Å; R128-T580 PolarHBondContact NH1-OG1 3.33Å; R128-T580 VanDerWaalsContact NH1-OG1 3.09Å
129T97.6Very high96.4Very high5 Ų513 Ų133%0.0316%0.063CC..Hα-helixtrans-55.6-37.1176.6-52.60000111.4D131 L132 K133 E166 R171T129-D131 PolarHBondContact O-N 3.1Å; T129-L132 PolarHBondContact O-N 3.01Å; T129-K133 HydrophobicContact CG2-CD 3.63Å; T129-K133 HydrophobicContact CG2-CG 4.12Å; T129-K133 WeakPolarHBondContact O-CB 3.47Å; T129-K133 VanDerWaalsContact O-CG 3.26Å; T129-K133 WeakPolarHBondContact O-CG 3.33Å; T129-K133 PolarHBondContact O-N 3.42Å; T129-E166 VanDerWaalsContact CB-OE2 3.26Å; T129-E166 WeakPolarHBondContact CB-OE2 3.33Å; T129-E166 PolarHBondContact N-OE2 2.83Å; T129-E166 PolarHBondContact OG1-OE2 3.22Å; T129-R171 HydrophobicContact CG2-CB 3.96Å; T129-R171 HydrophobicContact CG2-CG 3.98Å; T129-R171 PolarHBondContact OG1-NE 3.37Å; T129-R171 PolarHBondContact OG1-NH2 2.86Å
130H96.6Very high96.5Very high35 Ų3513 Ų1316%0.1626%0.063CC..Hα-helixtrans-52.2-51.6177.618079000113.4R128 K134R128-H130 PolarHBondContact O-N 3.11Å; H130-K134 VanDerWaalsContact NE2-CE 3.3Å; H130-K134 WeakPolarHBondContact NE2-CE 3.29Å; H130-K134 PolarHBondContact NE2-NZ 3.41Å; H130-K134 WeakPolarHBondContact O-CG 3.45Å; H130-K134 PolarHBondContact O-N 3.27Å
131D98Very high96.7Very high1 Ų114 Ų141%0.0057%0.067CC..Hα-helixtrans-77.8-31-176.2-59.7-44.9000111.9R128 T129 Y382 T386 Y390 T580R128-D131 PolarHBondContact O-N 3.13Å; T129-D131 PolarHBondContact O-N 3.1Å; D131-Y382 PolarHBondContact O-OH 3.01Å; D131-T386 HydrophobicContact CB-CG2 3.83Å; D131-Y390 WeakPolarHBondContact OD2-CE2 3.48Å; D131-Y390 PolarHBondContact OD2-OH 2.89Å; D131-T580 WeakPolarHBondContact OD2-CB 3.37Å; D131-T580 PolarHBondContact OD2-OG1 3.3Å
132L98.4Very high96.9Very high1 Ų115.9 Ų15.91%0.0058%0.078CC..Hα-helixtrans-64.9-43.8174-63.1169.7000111.1F115 V127 R128 T129 K134 I135 S136 L175 W383F115-L132 HydrophobicContact CB-CD2 4.07Å; F115-L132 HydrophobicContact CD1-CD2 4.01Å; F115-L132 HydrophobicContact CD2-CB 4.11Å; F115-L132 HydrophobicContact CD2-CD2 3.62Å; F115-L132 HydrophobicContact CD2-CG 4.31Å; F115-L132 HydrophobicContact CE1-CD2 4.35Å; F115-L132 HydrophobicContact CE2-CB 3.93Å; F115-L132 HydrophobicContact CE2-CD2 4.01Å; F115-L132 HydrophobicContact CG-CD2 3.62Å; F115-L132 HydrophobicContact CZ-CD2 4.36Å; V127-L132 HydrophobicContact CG1-CD1 4.3Å; V127-L132 HydrophobicContact CG1-CD2 3.77Å; V127-L132 HydrophobicContact CG1-CG 3.82Å; R128-L132 WeakPolarHBondContact O-CG 3.35Å; R128-L132 PolarHBondContact O-N 3.06Å; T129-L132 PolarHBondContact O-N 3.01Å; L132-K134 PolarHBondContact O-N 2.73Å; L132-I135 WeakPolarHBondContact O-CG2 3.44Å; L132-I135 PolarHBondContact O-N 2.7Å; L132-S136 PolarHBondContact O-N 2.82Å; L132-S136 VanDerWaalsContact O-N 3.16Å; L132-S136 PolarHBondContact O-OG 3.31Å; L132-L175 HydrophobicContact CB-CD1 4.48Å; L132-L175 HydrophobicContact CB-CD2 3.94Å; L132-L175 HydrophobicContact CD1-CD1 4.49Å; L132-W383 HydrophobicContact CD2-CH2 3.69Å; L132-W383 HydrophobicContact CD2-CZ2 3.99Å
133K97.1Very high97Very high68 Ų6815.9 Ų15.930%0.2968%0.078SC..Hα-helixtrans-62.5-41.1179.5-76.8170.368.8175.20112.7T129 I135 S136 P137 E174 L175 L178T129-K133 HydrophobicContact CG2-CD 3.63Å; T129-K133 HydrophobicContact CG2-CG 4.12Å; T129-K133 WeakPolarHBondContact O-CB 3.47Å; T129-K133 VanDerWaalsContact O-CG 3.26Å; T129-K133 WeakPolarHBondContact O-CG 3.33Å; T129-K133 PolarHBondContact O-N 3.42Å; K133-I135 VanDerWaalsContact C-N 3.3Å; K133-I135 PolarHBondContact O-N 3Å; K133-S136 WeakPolarHBondContact O-CB 3.4Å; K133-S136 PolarHBondContact O-N 3.2Å; K133-P137 WeakPolarHBondContact O-CD 3.38Å; K133-E174 HydrophobicContact CD-CB 4.13Å; K133-E174 WeakPolarHBondContact CD-OE2 3.45Å; K133-E174 VanDerWaalsContact CE-OE2 3.29Å; K133-E174 WeakPolarHBondContact CE-OE2 3.14Å; K133-E174 IonicContact NZ-OE1 2.81Å; K133-E174 PolarHBondContact NZ-OE1 3.02Å; K133-E174 VanDerWaalsContact NZ-OE1 3.09Å; K133-E174 IonicContact NZ-OE2 3.36Å; K133-E174 PolarHBondContact NZ-OE2 3.41Å; K133-L175 HydrophobicContact CG-CD2 4.04Å; K133-L178 HydrophobicContact CB-CD1 3.91Å; K133-L178 HydrophobicContact CG-CD1 3.91Å
134K96.7Very high97Very high72 Ų7217 Ų1731%0.3139%0.085SC..Hα-helixtrans-58-41.2-178-82.4-176.3170.8-167.60112.9V74 H130 L132 Y382V74-K134 VanDerWaalsContact CG1-O 3.27Å; V74-K134 WeakPolarHBondContact CG1-O 3.32Å; V74-K134 HydrophobicContact CG2-CB 3.91Å; V74-K134 HydrophobicContact CG2-CD 4.46Å; V74-K134 HydrophobicContact CG2-CG 4.45Å; H130-K134 VanDerWaalsContact NE2-CE 3.3Å; H130-K134 WeakPolarHBondContact NE2-CE 3.29Å; H130-K134 PolarHBondContact NE2-NZ 3.41Å; H130-K134 WeakPolarHBondContact O-CG 3.45Å; H130-K134 PolarHBondContact O-N 3.27Å; L132-K134 PolarHBondContact O-N 2.73Å; K134-Y382 HydrophobicContact CB-CE2 4.44Å; K134-Y382 WeakPolarHBondContact CB-OH 3.29Å
135I98.3Very high97.1Very high0 Ų018.7 Ų18.70%09%0.094CC..Hα-helixtrans-90.8-12.2-178.5-162.661.6000113.5P75 F115 L132 K133 F138 V139 Y379 Y382 W383P75-I135 HydrophobicContact CG-CD1 4.19Å; F115-I135 HydrophobicContact CE1-CG2 4.04Å; F115-I135 HydrophobicContact CZ-CG2 3.75Å; L132-I135 WeakPolarHBondContact O-CG2 3.44Å; L132-I135 PolarHBondContact O-N 2.7Å; K133-I135 VanDerWaalsContact C-N 3.3Å; K133-I135 PolarHBondContact O-N 3Å; I135-F138 HydrophobicContact CD1-CB 3.93Å; I135-F138 HydrophobicContact CD1-CD1 4.2Å; I135-F138 HydrophobicContact CD1-CG 4.26Å; I135-F138 HydrophobicContact CG1-CB 4.49Å; I135-F138 WeakPolarHBondContact O-CB 3.48Å; I135-F138 PolarHBondContact O-N 3.36Å; I135-V139 PolarHBondContact O-N 2.97Å; I135-V139 VanDerWaalsContact O-N 3.16Å; I135-Y379 HydrophobicContact CD1-CD2 4.22Å; I135-Y379 HydrophobicContact CG1-CD2 3.72Å; I135-Y379 HydrophobicContact CG1-CE2 3.67Å; I135-Y379 HydrophobicContact CG2-CE2 4.42Å; I135-Y382 HydrophobicContact CB-CD1 3.71Å; I135-Y382 HydrophobicContact CB-CE1 3.47Å; I135-Y382 VanDerWaalsContact CB-CE1 3.47Å; I135-Y382 HydrophobicContact CB-CE2 4.42Å; I135-Y382 HydrophobicContact CB-CG 4.28Å; I135-Y382 HydrophobicContact CD1-CD1 3.73Å; I135-Y382 HydrophobicContact CD1-CD2 4.02Å; I135-Y382 HydrophobicContact CD1-CE1 4.34Å; I135-Y382 HydrophobicContact CD1-CG 3.54Å; I135-Y382 HydrophobicContact CG1-CD1 3.59Å; I135-Y382 HydrophobicContact CG1-CE1 3.93Å; I135-Y382 HydrophobicContact CG1-CG 3.98Å; I135-Y382 HydrophobicContact CG2-CD1 4.18Å; I135-Y382 HydrophobicContact CG2-CE1 3.72Å; I135-W383 HydrophobicContact CG2-CZ2 4.08Å
136S98.3Very high97.3Very high0 Ų018.4 Ų18.40%09%0.092CC..Hα-helixtrans-54.5-45.8-176.4-70.50000114.6L132 K133 F138 V139 S140 L175L132-S136 PolarHBondContact O-N 2.82Å; L132-S136 VanDerWaalsContact O-N 3.16Å; L132-S136 PolarHBondContact O-OG 3.31Å; K133-S136 WeakPolarHBondContact O-CB 3.4Å; K133-S136 PolarHBondContact O-N 3.2Å; S136-F138 VanDerWaalsContact C-N 3.26Å; S136-F138 PolarHBondContact O-N 2.94Å; S136-V139 PolarHBondContact O-N 3.49Å; S136-S140 PolarHBondContact O-N 2.84Å; S136-L175 WeakPolarHBondContact OG-CD2 3.4Å
137P97.7Very high97.5Very high40 Ų4017.3 Ų17.326%0.269%0.088SC..Hα-helixtrans-58.5-38.2175.6-25.535.6000112.8V77 K133 V139 S140 H141 L178V77-P137 HydrophobicContact CG1-CB 4.45Å; V77-P137 HydrophobicContact CG2-CB 4.43Å; K133-P137 WeakPolarHBondContact O-CD 3.38Å; P137-V139 PolarHBondContact O-N 3.46Å; P137-S140 PolarHBondContact O-N 3.13Å; P137-H141 PolarHBondContact O-CD2 3Å; P137-H141 PolarHBondContact O-N 3.02Å; P137-L178 HydrophobicContact CG-CD2 4.29Å
138F98.2Very high97.5Very high1 Ų117.3 Ų17.30%0.0049%0.088CC..Hα-helixtrans-64.4-42.7178.1-175.7-96.7000112P75 V77 I135 S136 H141 N142 F143 K375 D378 Y379P75-F138 HydrophobicContact CB-CD2 3.61Å; P75-F138 HydrophobicContact CB-CE2 3.58Å; P75-F138 HydrophobicContact CB-CG 4.26Å; P75-F138 HydrophobicContact CB-CZ 4.21Å; P75-F138 HydrophobicContact CG-CD2 4.27Å; P75-F138 HydrophobicContact CG-CE2 4.31Å; P75-F138 HydrophobicContact CG-CG 4.45Å; V77-F138 VanDerWaalsContact CG1-CA 3.45Å; V77-F138 HydrophobicContact CG1-CB 3.92Å; V77-F138 HydrophobicContact CG1-CD2 3.96Å; V77-F138 HydrophobicContact CG1-CG 4.43Å; I135-F138 HydrophobicContact CD1-CB 3.93Å; I135-F138 HydrophobicContact CD1-CD1 4.2Å; I135-F138 HydrophobicContact CD1-CG 4.26Å; I135-F138 HydrophobicContact CG1-CB 4.49Å; I135-F138 WeakPolarHBondContact O-CB 3.48Å; I135-F138 PolarHBondContact O-N 3.36Å; S136-F138 VanDerWaalsContact C-N 3.26Å; S136-F138 PolarHBondContact O-N 2.94Å; F138-H141 PolarHBondContact O-N 3.16Å; F138-N142 VanDerWaalsContact CD2-ND2 3.29Å; F138-N142 WeakPolarHBondContact CD2-ND2 3.3Å; F138-N142 HydrophobicContact CE1-CB 4.42Å; F138-N142 VanDerWaalsContact CE2-ND2 3.29Å; F138-N142 WeakPolarHBondContact CE2-ND2 3.31Å; F138-N142 HydrophobicContact CZ-CB 4.33Å; F138-N142 WeakPolarHBondContact O-CB 3.33Å; F138-N142 PolarHBondContact O-N 3.36Å; F138-N142 PolarHBondContact O-ND2 3.35Å; F138-F143 HydrophobicContact CD1-CE2 4.14Å; F138-F143 AromaticContact CE1-CE2 3.75Å; F138-F143 HydrophobicContact CE1-CE2 3.75Å; F138-K375 HydrophobicContact CE2-CD 4.46Å; F138-K375 HydrophobicContact CZ-CB 4.36Å; F138-K375 HydrophobicContact CZ-CD 4.04Å; F138-D378 HydrophobicContact CE1-CB 4.19Å; F138-D378 HydrophobicContact CE2-CB 4.2Å; F138-D378 HydrophobicContact CZ-CB 3.53Å; F138-Y379 HydrophobicContact CD1-CD2 4.47Å
139V98.2Very high97.6Very high0 Ų017.3 Ų17.30%09%0.087CC..Hα-helixtrans-60.1-50174.7177.90000110.4F115 I135 S136 P137 H141 N142 F143 I179 Y379F115-V139 HydrophobicContact CE1-CG2 4.18Å; F115-V139 HydrophobicContact CZ-CG2 4.23Å; I135-V139 PolarHBondContact O-N 2.97Å; I135-V139 VanDerWaalsContact O-N 3.16Å; S136-V139 PolarHBondContact O-N 3.49Å; P137-V139 PolarHBondContact O-N 3.46Å; V139-H141 VanDerWaalsContact C-N 3.31Å; V139-H141 PolarHBondContact O-N 3.3Å; V139-N142 PolarHBondContact O-N 2.9Å; V139-F143 HydrophobicContact CG1-CB 4.33Å; V139-F143 WeakPolarHBondContact O-CA 3.37Å; V139-F143 WeakPolarHBondContact O-CB 3.44Å; V139-F143 PolarHBondContact O-N 2.97Å; V139-I179 HydrophobicContact CB-CD1 4.42Å; V139-I179 HydrophobicContact CG1-CD1 4.46Å; V139-Y379 HydrophobicContact CG2-CD2 4.39Å; V139-Y379 HydrophobicContact CG2-CE2 3.68Å
140S97.7Very high97.6Very high1 Ų117 Ų171%0.0079%0.086CC..Hα-helixtrans-57.6-40.2-179.4-172.50000113.1P82 S136 P137 L178 N181P82-S140 WeakPolarHBondContact CB-OG 3.3Å; P82-S140 VanDerWaalsContact CG-OG 3.27Å; P82-S140 WeakPolarHBondContact CG-OG 3.22Å; S136-S140 PolarHBondContact O-N 2.84Å; P137-S140 PolarHBondContact O-N 3.13Å; S140-L178 WeakPolarHBondContact CB-O 3.47Å; S140-N181 PolarHBondContact O-ND2 2.76Å; S140-N181 PolarHBondContact OG-OD1 3.17Å
141H97.6Very high97.7Very high35 Ų3515.5 Ų15.516%0.1628%0.079CC..Hα-helixtrans-80-38.5-178.6-81.6-100.5000114.3T78 G80 P137 F138 V139T78-H141 PolarHBondContact O-CE1 3.43Å; T78-H141 VanDerWaalsContact O-CE1 3.29Å; G80-H141 PolarHBondContact O-CE1 3.08Å; G80-H141 VanDerWaalsContact O-CE1 3.3Å; G80-H141 PolarHBondContact O-NE2 2.93Å; P137-H141 PolarHBondContact O-CD2 3Å; P137-H141 PolarHBondContact O-N 3.02Å; F138-H141 PolarHBondContact O-N 3.16Å; V139-H141 VanDerWaalsContact C-N 3.31Å; V139-H141 PolarHBondContact O-N 3.3Å
142N97.4Very high97.7Very high40 Ų4015.5 Ų15.521%0.2148%0.079CC..Hα-helixtrans-104.3-13-168.4-63.3-84.7000114.2F138 V139 K375F138-N142 VanDerWaalsContact CD2-ND2 3.29Å; F138-N142 WeakPolarHBondContact CD2-ND2 3.3Å; F138-N142 HydrophobicContact CE1-CB 4.42Å; F138-N142 VanDerWaalsContact CE2-ND2 3.29Å; F138-N142 WeakPolarHBondContact CE2-ND2 3.31Å; F138-N142 HydrophobicContact CZ-CB 4.33Å; F138-N142 WeakPolarHBondContact O-CB 3.33Å; F138-N142 PolarHBondContact O-N 3.36Å; F138-N142 PolarHBondContact O-ND2 3.35Å; V139-N142 PolarHBondContact O-N 2.9Å; N142-K375 HydrophobicContact CB-CB 4.13Å; N142-K375 HydrophobicContact CB-CD 4.39Å; N142-K375 HydrophobicContact CB-CG 4.11Å; N142-K375 WeakPolarHBondContact OD1-CD 2.97Å; N142-K375 WeakPolarHBondContact OD1-CE 3.35Å
143F97.6Very high97.4Very high0 Ų015.5 Ų15.50%08%0.079CC..  trans-125.834.8-177.7-62.2-92.4000111.6F138 V139 N145 L146 M355 I371 K375 V376 Y379F138-F143 HydrophobicContact CD1-CE2 4.14Å; F138-F143 AromaticContact CE1-CE2 3.75Å; F138-F143 HydrophobicContact CE1-CE2 3.75Å; V139-F143 HydrophobicContact CG1-CB 4.33Å; V139-F143 WeakPolarHBondContact O-CA 3.37Å; V139-F143 WeakPolarHBondContact O-CB 3.44Å; V139-F143 PolarHBondContact O-N 2.97Å; F143-N145 PolarHBondContact O-N 3.45Å; F143-L146 HydrophobicContact CB-CD1 3.6Å; F143-L146 HydrophobicContact CB-CG 3.84Å; F143-L146 HydrophobicContact CG-CD1 4.39Å; F143-L146 WeakPolarHBondContact O-CB 3.36Å; F143-L146 WeakPolarHBondContact O-CG 3.44Å; F143-L146 PolarHBondContact O-N 2.94Å; F143-L146 VanDerWaalsContact O-N 3.12Å; F143-M355 HydrophobicContact CD1-SD 4.31Å; F143-M355 HydrophobicContact CE1-SD 3.66Å; F143-M355 HydrophobicContact CZ-SD 4.42Å; F143-I371 HydrophobicContact CD1-CD1 4.48Å; F143-I371 HydrophobicContact CD1-CG2 4.1Å; F143-I371 HydrophobicContact CE1-CG2 3.86Å; F143-K375 HydrophobicContact CZ-CB 4.42Å; F143-V376 HydrophobicContact CE1-CG2 4.14Å; F143-V376 HydrophobicContact CZ-CG2 4.45Å; F143-Y379 HydrophobicContact CE1-CD1 4.44Å; F143-Y379 HydrophobicContact CE2-CD1 4.02Å; F143-Y379 HydrophobicContact CE2-CG 4.12Å; F143-Y379 AromaticContact CZ-CD1 3.76Å; F143-Y379 HydrophobicContact CZ-CD1 3.76Å; F143-Y379 HydrophobicContact CZ-CG 4.13Å
144S94.6Very high96.9Very high22 Ų2212.9 Ų12.915%0.1547%0.068CC..THydrogen-bonded Turntrans-62.4-20.9179.750.30000113.9G85 N181G85-S144 VanDerWaalsContact CA-O 3.24Å; G85-S144 WeakPolarHBondContact CA-O 3.37Å; S144-N181 WeakPolarHBondContact CB-ND2 3.33Å
145N94.1Very high96.4Very high42 Ų4210 Ų1023%0.2256%0.058CC..THydrogen-bonded Turntrans-89.74.5176.668.2-37000114.3F143 T369 I371F143-N145 PolarHBondContact O-N 3.45Å; N145-T369 PolarHBondContact ND2-O 2.92Å; N145-I371 VanDerWaalsContact ND2-CG1 3.33Å; N145-I371 WeakPolarHBondContact ND2-CG1 3.21Å
146L98.5Very high96.1Very high0 Ų010.3 Ų10.30%06%0.06CC..  trans-59.6141.1169.7-73173.3000110.3L110 D112 F143 S148 V182 I371L110-L146 HydrophobicContact CB-CD2 3.93Å; L110-L146 WeakPolarHBondContact O-CD2 3.39Å; D112-L146 HydrophobicContact CB-CD1 3.9Å; D112-L146 HydrophobicContact CB-CD2 4.44Å; F143-L146 HydrophobicContact CB-CD1 3.6Å; F143-L146 HydrophobicContact CB-CG 3.84Å; F143-L146 HydrophobicContact CG-CD1 4.39Å; F143-L146 WeakPolarHBondContact O-CB 3.36Å; F143-L146 WeakPolarHBondContact O-CG 3.44Å; F143-L146 PolarHBondContact O-N 2.94Å; F143-L146 VanDerWaalsContact O-N 3.12Å; L146-S148 VanDerWaalsContact C-N 3.3Å; L146-V182 HydrophobicContact CB-CG1 4.01Å; L146-I371 HydrophobicContact CD2-CD1 4.24Å
147F98.8Very high95.9Very high0 Ų010.4 Ų10.40%06%0.061CC..SBendtrans-58.8-48170.1161.6-101000110.1F98 V102 L109 L110 M111 P183 Q185 I218 I282 H314 V338F98-F147 HydrophobicContact CE1-CD2 4.42Å; F98-F147 AromaticContact CE1-CE2 3.61Å; F98-F147 HydrophobicContact CE1-CE2 3.61Å; F98-F147 HydrophobicContact CE1-CZ 4.15Å; F98-F147 AromaticContact CZ-CD2 3.81Å; F98-F147 HydrophobicContact CZ-CD2 3.81Å; F98-F147 AromaticContact CZ-CE2 3.43Å; F98-F147 HydrophobicContact CZ-CE2 3.43Å; F98-F147 VanDerWaalsContact CZ-CE2 3.43Å; F98-F147 HydrophobicContact CZ-CZ 4.16Å; V102-F147 HydrophobicContact CG1-CD2 4.16Å; V102-F147 HydrophobicContact CG1-CE2 4.17Å; V102-F147 HydrophobicContact CG2-CD2 3.77Å; V102-F147 HydrophobicContact CG2-CE2 3.78Å; L109-F147 HydrophobicContact CB-CB 3.97Å; L109-F147 HydrophobicContact CD1-CB 4.45Å; L110-F147 PolarHBondContact O-N 3.09Å; M111-F147 HydrophobicContact CB-CD1 4.17Å; M111-F147 HydrophobicContact CG-CD1 4.49Å; F147-P183 WeakPolarHBondContact O-CD 3.3Å; F147-P183 VanDerWaalsContact O-CG 3.26Å; F147-P183 WeakPolarHBondContact O-CG 3.47Å; F147-Q185 VanDerWaalsContact CE1-OE1 3.25Å; F147-I218 HydrophobicContact CE1-CD1 3.96Å; F147-I218 HydrophobicContact CE2-CD1 4.31Å; F147-I218 HydrophobicContact CZ-CD1 3.73Å; F147-I282 HydrophobicContact CE2-CD1 3.55Å; F147-I282 HydrophobicContact CZ-CD1 3.44Å; F147-I282 VanDerWaalsContact CZ-CD1 3.44Å; F147-H314 AromaticContact CD1-CE1 3.69Å; F147-H314 AromaticContact CE1-CE1 3.37Å; F147-H314 WeakPolarHBondContact CE1-CE1 3.5Å; F147-H314 AromaticContact CE1-ND1 3.45Å; F147-H314 WeakPolarHBondContact CE1-ND1 3.31Å; F147-V338 HydrophobicContact CB-CG1 3.74Å; F147-V338 HydrophobicContact CB-CG2 4.22Å; F147-V338 HydrophobicContact CD1-CG1 3.67Å; F147-V338 HydrophobicContact CD1-CG2 4.29Å; F147-V338 HydrophobicContact CD2-CG1 4.48Å; F147-V338 HydrophobicContact CD2-CG2 3.74Å; F147-V338 HydrophobicContact CE1-CG1 4.38Å; F147-V338 HydrophobicContact CE2-CG2 4.14Å; F147-V338 HydrophobicContact CG-CB 4.43Å; F147-V338 HydrophobicContact CG-CG1 3.71Å; F147-V338 HydrophobicContact CG-CG2 3.82Å
148S98.8Very high95.8Very high0 Ų08.8 Ų8.80%05%0.05CC..EExtended strand (participates in β ladder)trans-162.6167174.3660000111.2M111 D112 L146 P183 Q185M111-S148 WeakPolarHBondContact CA-O 3.35Å; M111-S148 WeakPolarHBondContact CG-O 3.32Å; M111-S148 WeakPolarHBondContact CG-OG 3.26Å; D112-S148 PolarHBondContact N-O 2.99Å; L146-S148 VanDerWaalsContact C-N 3.3Å; S148-P183 CarbonylContact C-O 3.58Å; S148-P183 VanDerWaalsContact CA-O 3.27Å; S148-P183 WeakPolarHBondContact CA-O 3.34Å; S148-P183 WeakPolarHBondContact CB-O 3.47Å; S148-Q185 PolarHBondContact OG-OE1 3.5Å
149L98.8Very high95.6Very high0 Ų09.1 Ų9.10%05%0.052CC..EExtended strand (participates in β ladder)trans-112.2115.1168.8177.667.4000107.9D112 F115 N151 I179 V182 P183 F184 Q185D112-L149 HydrophobicContact CB-CD1 3.8Å; F115-L149 HydrophobicContact CB-CD1 4.13Å; F115-L149 HydrophobicContact CB-CG 4.37Å; F115-L149 HydrophobicContact CD1-CD1 3.85Å; F115-L149 HydrophobicContact CD1-CD2 4.39Å; F115-L149 HydrophobicContact CD2-CD2 3.88Å; F115-L149 HydrophobicContact CE1-CD1 4.44Å; F115-L149 HydrophobicContact CE2-CD2 4.09Å; F115-L149 HydrophobicContact CG-CD1 3.95Å; F115-L149 HydrophobicContact CG-CD2 4.04Å; F115-L149 HydrophobicContact CG-CG 4.27Å; F115-L149 HydrophobicContact CZ-CD2 4.45Å; L149-N151 HydrophobicContact CG-CB 4.33Å; L149-N151 PolarHBondContact O-N 2.98Å; L149-I179 HydrophobicContact CD2-CD1 3.6Å; L149-V182 HydrophobicContact CB-CG1 4.14Å; L149-P183 PolarHBondContact N-O 3.15Å; L149-F184 HydrophobicContact CB-CD1 4.4Å; L149-F184 HydrophobicContact CD2-CE1 4.01Å; L149-Q185 PolarHBondContact O-N 3.43Å
150E98.8Very high95.5Very high0 Ų09.2 Ų9.20%05%0.052CC..EExtended strand (participates in β ladder)trans-81.4112.6174.3-167-166.6-125.900109.5M111 D112 F115 R116 D117 Q185 R220M111-E150 HydrophobicContact CE-CB 3.56Å; M111-E150 HydrophobicContact CE-CG 4.24Å; M111-E150 HydrophobicContact SD-CB 3.97Å; D112-E150 PolarHBondContact O-N 3.27Å; F115-E150 CarbonylContact C-O 3.57Å; F115-E150 WeakPolarHBondContact CB-O 3.48Å; R116-E150 HydrophobicContact CB-CG 4.07Å; R116-E150 VanDerWaalsContact CB-O 3.25Å; R116-E150 WeakPolarHBondContact CB-O 3.43Å; R116-E150 HydrophobicContact CG-CG 4.43Å; R116-E150 IonicContact CZ-OE1 3.78Å; R116-E150 IonicContact CZ-OE2 2.7Å; R116-E150 PolarHBondContact N-O 3.12Å; R116-E150 VanDerWaalsContact NE-CD 3.29Å; R116-E150 IonicContact NE-OE1 2.67Å; R116-E150 IonicContact NE-OE2 2.76Å; R116-E150 PolarHBondContact NE-OE2 2.89Å; R116-E150 IonicContact NH2-OE1 2.72Å; R116-E150 PolarHBondContact NH2-OE1 2.86Å; R116-E150 IonicContact NH2-OE2 3.63Å; R116-E150 PolarHBondContact NH2-OE2 3Å; D117-E150 WeakPolarHBondContact CB-OE2 3.26Å; E150-Q185 WeakPolarHBondContact CA-O 3.28Å; E150-Q185 HydrophobicContact CB-CB 4.39Å; E150-Q185 HydrophobicContact CG-CG 4.43Å; E150-R220 IonicContact OE1-NH1 3.06Å
151N98.3Very high95.5Very high2 Ų29.3 Ų9.31%0.0115%0.053CC..EExtended strand (participates in β ladder)trans-135.75.4-170.764.720000114.2F115 L149 L175 F184 Q185F115-N151 HydrophobicContact CB-CB 3.65Å; F115-N151 HydrophobicContact CD2-CB 4.26Å; F115-N151 HydrophobicContact CG-CB 4.41Å; L149-N151 HydrophobicContact CG-CB 4.33Å; L149-N151 PolarHBondContact O-N 2.98Å; N151-L175 HydrophobicContact CB-CD1 4.46Å; N151-F184 WeakPolarHBondContact ND2-CD1 3.43Å; N151-F184 WeakPolarHBondContact ND2-CD2 3.17Å; N151-F184 WeakPolarHBondContact ND2-CE1 2.95Å; N151-F184 WeakPolarHBondContact ND2-CE2 3.36Å; N151-F184 WeakPolarHBondContact ND2-CG 3.26Å; N151-F184 WeakPolarHBondContact ND2-CZ 3.42Å; N151-Q185 PolarHBondContact N-O 2.81Å; N151-Q185 VanDerWaalsContact N-O 3.17Å
152W97.6Very high95.4Very high2 Ų211.9 Ų11.91%0.0086%0.061CC..EExtended strand (participates in β ladder)trans-155.4172.8-172.6-131.365.5000114.1F157 P168 W169 L172 M186 L187 F207 A211 M216W152-F157 AromaticContact CH2-CD2 3.58Å; W152-F157 HydrophobicContact CH2-CD2 3.58Å; W152-F157 AromaticContact CH2-CE2 3.43Å; W152-F157 HydrophobicContact CH2-CE2 3.43Å; W152-F157 VanDerWaalsContact CH2-CE2 3.43Å; W152-F157 AromaticContact CZ2-CD2 3.72Å; W152-F157 HydrophobicContact CZ2-CD2 3.72Å; W152-F157 AromaticContact CZ2-CE2 3.77Å; W152-F157 HydrophobicContact CZ2-CE2 3.77Å; W152-F157 HydrophobicContact CZ3-CD2 4.06Å; W152-F157 HydrophobicContact CZ3-CE2 4.19Å; W152-P168 HydrophobicContact CZ2-CB 3.9Å; W152-P168 WeakPolarHBondContact CZ2-O 3.37Å; W152-P168 PolarHBondContact NE1-O 2.81Å; W152-W169 AromaticContact CH2-CD2 3.69Å; W152-W169 HydrophobicContact CH2-CD2 3.69Å; W152-W169 AromaticContact CH2-CE2 3.93Å; W152-W169 AromaticContact CH2-CE3 3.45Å; W152-W169 HydrophobicContact CH2-CE3 3.45Å; W152-W169 VanDerWaalsContact CH2-CE3 3.45Å; W152-W169 HydrophobicContact CH2-CG 4.48Å; W152-W169 AromaticContact CH2-CH2 3.72Å; W152-W169 HydrophobicContact CH2-CH2 3.72Å; W152-W169 AromaticContact CH2-CZ2 3.95Å; W152-W169 HydrophobicContact CH2-CZ2 3.95Å; W152-W169 AromaticContact CH2-CZ3 3.46Å; W152-W169 HydrophobicContact CH2-CZ3 3.46Å; W152-W169 VanDerWaalsContact CH2-CZ3 3.46Å; W152-W169 AromaticContact CZ2-CD2 3.99Å; W152-W169 HydrophobicContact CZ2-CD2 3.99Å; W152-W169 AromaticContact CZ2-CE3 3.97Å; W152-W169 HydrophobicContact CZ2-CE3 3.97Å; W152-W169 HydrophobicContact CZ2-CG 4.34Å; W152-W169 HydrophobicContact CZ2-CZ3 4.41Å; W152-W169 HydrophobicContact CZ3-CE3 4.43Å; W152-W169 HydrophobicContact CZ3-CH2 4.22Å; W152-W169 HydrophobicContact CZ3-CZ3 4.07Å; W152-L172 HydrophobicContact CD2-CB 4.5Å; W152-L172 HydrophobicContact CD2-CD2 4.23Å; W152-L172 HydrophobicContact CE3-CD2 4.31Å; W152-L172 HydrophobicContact CH2-CD2 4.29Å; W152-L172 HydrophobicContact CZ2-CB 4.23Å; W152-L172 HydrophobicContact CZ2-CD2 4.23Å; W152-L172 HydrophobicContact CZ3-CD2 4.34Å; W152-M186 HydrophobicContact CB-CB 4.1Å; W152-M186 HydrophobicContact CE3-CE 4.38Å; W152-M186 HydrophobicContact CE3-SD 4.27Å; W152-M186 VanDerWaalsContact O-CA 3.28Å; W152-M186 WeakPolarHBondContact O-CA 3.5Å; W152-M186 WeakPolarHBondContact O-CB 3.39Å; W152-L187 PolarHBondContact O-N 3.16Å; W152-F207 HydrophobicContact CH2-CZ 4.33Å; W152-F207 HydrophobicContact CZ3-CE1 4.33Å; W152-F207 AromaticContact CZ3-CZ 3.76Å; W152-F207 HydrophobicContact CZ3-CZ 3.76Å; W152-A211 HydrophobicContact CZ3-CB 4.4Å; W152-M216 HydrophobicContact CB-CE 3.46Å; W152-M216 VanDerWaalsContact CB-CE 3.46Å; W152-M216 HydrophobicContact CD2-CE 4.36Å; W152-M216 HydrophobicContact CE3-CE 4.22Å; W152-M216 HydrophobicContact CG-CE 4.11Å
153G92.4Very high95.3Very high0 Ų012.5 Ų12.50%06%0.062CC..EExtended strand (participates in β ladder)trans86.2-178.3-179.300000114.9A155 A156 L187G153-A155 PolarHBondContact O-N 3.37Å; G153-A156 WeakPolarHBondContact O-CB 3.3Å; G153-A156 PolarHBondContact O-N 3.34Å; G153-L187 WeakPolarHBondContact CA-O 3.49Å
154D86.9Confident95.2Very high14 Ų1412.6 Ų12.68%0.0756%0.063CC..THydrogen-bonded Turntrans42.4-132.5-174.5-166.522.5000113.2R116 Q120 A156 F157 L187R116-D154 IonicContact NH1-OD2 3.58Å; Q120-D154 PolarHBondContact NE2-OD2 3.24Å; D154-A156 PolarHBondContact O-N 3.38Å; D154-F157 PolarHBondContact O-N 3.27Å; D154-L187 HydrophobicContact CB-CB 4.29Å; D154-L187 HydrophobicContact CB-CD2 3.95Å; D154-L187 HydrophobicContact CB-CG 4.39Å; D154-L187 PolarHBondContact N-O 3.21Å
155A86.8Confident95.3Very high12 Ų1212 Ų1210%0.0996%0.058CC..Hα-helixtrans-65.6-22.1-175.400000113.7T125 G153 F157 D158 V159T125-A155 HydrophobicContact CG2-CB 4.49Å; G153-A155 PolarHBondContact O-N 3.37Å; A155-F157 PolarHBondContact O-N 3.24Å; A155-D158 PolarHBondContact O-N 2.83Å; A155-V159 HydrophobicContact CB-CG2 4.4Å; A155-V159 VanDerWaalsContact O-CB 3.25Å; A155-V159 WeakPolarHBondContact O-CB 3.49Å; A155-V159 WeakPolarHBondContact O-CG2 3.46Å; A155-V159 PolarHBondContact O-N 3.2Å
156A91.2Very high95.3Very high6 Ų610.1 Ų10.15%0.055%0.048CC..Hα-helixtrans-61.3-31.8-176.800000112.2R116 T125 G153 D154 A160R116-A156 HydrophobicContact CG-CB 4.31Å; T125-A156 HydrophobicContact CG2-CB 4.11Å; G153-A156 WeakPolarHBondContact O-CB 3.3Å; G153-A156 PolarHBondContact O-N 3.34Å; D154-A156 PolarHBondContact O-N 3.38Å; A156-A160 VanDerWaalsContact O-CB 3.25Å; A156-A160 WeakPolarHBondContact O-CB 3.37Å; A156-A160 PolarHBondContact O-N 3.1Å; A156-A160 VanDerWaalsContact O-N 3.1Å
157F95Very high95.2Very high1 Ų111.5 Ų11.50%0.0046%0.058CC..Hα-helixtrans-68-51.5178.6-165.8-83.1000112.2W152 D154 A155 M161 P168 W169 V194 F207 Y558W152-F157 AromaticContact CH2-CD2 3.58Å; W152-F157 HydrophobicContact CH2-CD2 3.58Å; W152-F157 AromaticContact CH2-CE2 3.43Å; W152-F157 HydrophobicContact CH2-CE2 3.43Å; W152-F157 VanDerWaalsContact CH2-CE2 3.43Å; W152-F157 AromaticContact CZ2-CD2 3.72Å; W152-F157 HydrophobicContact CZ2-CD2 3.72Å; W152-F157 AromaticContact CZ2-CE2 3.77Å; W152-F157 HydrophobicContact CZ2-CE2 3.77Å; W152-F157 HydrophobicContact CZ3-CD2 4.06Å; W152-F157 HydrophobicContact CZ3-CE2 4.19Å; D154-F157 PolarHBondContact O-N 3.27Å; A155-F157 PolarHBondContact O-N 3.24Å; F157-M161 HydrophobicContact CD1-CE 3.7Å; F157-M161 HydrophobicContact CE1-CE 3.48Å; F157-M161 VanDerWaalsContact CE1-CE 3.48Å; F157-M161 HydrophobicContact CZ-CE 4.48Å; F157-P168 HydrophobicContact CD1-CG 4.28Å; F157-P168 HydrophobicContact CD2-CB 3.85Å; F157-P168 HydrophobicContact CD2-CG 3.75Å; F157-P168 HydrophobicContact CE1-CG 4.22Å; F157-P168 HydrophobicContact CE2-CB 4.16Å; F157-P168 HydrophobicContact CE2-CG 3.68Å; F157-P168 HydrophobicContact CG-CB 4.28Å; F157-P168 HydrophobicContact CG-CG 4.06Å; F157-P168 HydrophobicContact CZ-CG 3.93Å; F157-W169 HydrophobicContact CE2-CD2 4.31Å; F157-W169 AromaticContact CE2-CE2 3.54Å; F157-W169 HydrophobicContact CE2-CH2 4.48Å; F157-W169 AromaticContact CE2-CZ2 3.63Å; F157-W169 HydrophobicContact CE2-CZ2 3.63Å; F157-W169 AromaticContact CE2-NE1 3.51Å; F157-W169 AromaticContact CZ-CE2 3.73Å; F157-W169 AromaticContact CZ-CZ2 3.83Å; F157-W169 HydrophobicContact CZ-CZ2 3.83Å; F157-W169 AromaticContact CZ-NE1 3.35Å; F157-W169 VanDerWaalsContact CZ-NE1 3.35Å; F157-V194 HydrophobicContact CB-CB 4.1Å; F157-V194 HydrophobicContact CB-CG1 4.45Å; F157-V194 HydrophobicContact CB-CG2 4.17Å; F157-V194 HydrophobicContact CD1-CG2 3.89Å; F157-V194 HydrophobicContact CD2-CG2 4.21Å; F157-V194 HydrophobicContact CE1-CG2 4.31Å; F157-V194 HydrophobicContact CG-CB 4.29Å; F157-V194 HydrophobicContact CG-CG2 3.82Å; F157-F207 HydrophobicContact CD2-CE2 4.41Å; F157-F207 HydrophobicContact CD2-CZ 4.35Å; F157-F207 AromaticContact CE2-CE2 3.92Å; F157-F207 HydrophobicContact CE2-CE2 3.92Å; F157-F207 HydrophobicContact CE2-CZ 4.22Å; F157-F207 HydrophobicContact CZ-CE2 4.16Å; F157-Y558 AromaticContact CD1-CD2 3.83Å; F157-Y558 HydrophobicContact CD1-CD2 3.83Å; F157-Y558 AromaticContact CD1-CE2 3.81Å; F157-Y558 HydrophobicContact CD1-CE2 3.81Å; F157-Y558 AromaticContact CE1-CD2 4Å; F157-Y558 HydrophobicContact CE1-CD2 4Å; F157-Y558 HydrophobicContact CE1-CE2 4.38Å
158D94.3Very high95.2Very high7 Ų711.6 Ų11.64%0.0376%0.058CC..Hα-helixtrans-64.7-46.9176.9177.955.6000111.3A155 A160 M161 R162 Y196 Y558A155-D158 PolarHBondContact O-N 2.83Å; D158-A160 VanDerWaalsContact C-N 3.34Å; D158-A160 PolarHBondContact O-N 2.79Å; D158-M161 PolarHBondContact O-N 3.32Å; D158-R162 WeakPolarHBondContact O-CB 3.28Å; D158-R162 PolarHBondContact O-N 2.75Å; D158-R162 IonicContact OD1-CZ 3.48Å; D158-R162 VanDerWaalsContact OD1-CZ 3.26Å; D158-R162 IonicContact OD1-NE 3.3Å; D158-R162 PolarHBondContact OD1-NE 3.29Å; D158-R162 IonicContact OD1-NH2 3.94Å; D158-R162 PolarHBondContact OD1-NH2 2.72Å; D158-R162 IonicContact OD2-CZ 2.57Å; D158-R162 IonicContact OD2-NE 3.26Å; D158-R162 PolarHBondContact OD2-NE 3.21Å; D158-R162 IonicContact OD2-NH2 2.77Å; D158-R162 PolarHBondContact OD2-NH2 2.7Å; D158-Y196 HydrophobicContact CB-CE2 4.43Å; D158-Y558 HydrophobicContact CB-CE1 3.95Å; D158-Y558 HydrophobicContact CB-CE2 4.3Å
159V94.6Very high95.1Very high8 Ų811.7 Ų11.75%0.0486%0.058CC..Hα-helixtrans-64.9-37.4-174.1169.40000112.1T125 R126 A155 M161 F163 L164T125-V159 HydrophobicContact CG2-CB 4.15Å; T125-V159 HydrophobicContact CG2-CG1 4.23Å; T125-V159 HydrophobicContact CG2-CG2 4.28Å; T125-V159 WeakPolarHBondContact O-CG1 3.39Å; R126-V159 VanDerWaalsContact NH1-CG1 3.27Å; A155-V159 HydrophobicContact CB-CG2 4.4Å; A155-V159 VanDerWaalsContact O-CB 3.25Å; A155-V159 WeakPolarHBondContact O-CB 3.49Å; A155-V159 WeakPolarHBondContact O-CG2 3.46Å; A155-V159 PolarHBondContact O-N 3.2Å; V159-M161 VanDerWaalsContact C-N 3.33Å; V159-M161 PolarHBondContact O-N 3.49Å; V159-F163 HydrophobicContact CB-CD2 4.21Å; V159-F163 HydrophobicContact CG1-CB 4.24Å; V159-F163 HydrophobicContact CG1-CD2 4.02Å; V159-F163 HydrophobicContact CG2-CD2 3.95Å; V159-F163 HydrophobicContact CG2-CE2 4.3Å; V159-F163 PolarHBondContact O-N 3.01Å; V159-L164 HydrophobicContact CG1-CD1 4.49Å; V159-L164 HydrophobicContact CG1-CG 4.37Å; V159-L164 PolarHBondContact O-N 3.33Å; V159-L164 VanDerWaalsContact O-N 3.14Å
160A96.8Very high95Very high1 Ų115.3 Ų15.31%0.0087%0.074CC..Iπ-helixtrans-55.5-49.5175.800000111A156 D158 L164 S165 E166 P168A156-A160 VanDerWaalsContact O-CB 3.25Å; A156-A160 WeakPolarHBondContact O-CB 3.37Å; A156-A160 PolarHBondContact O-N 3.1Å; A156-A160 VanDerWaalsContact O-N 3.1Å; D158-A160 VanDerWaalsContact C-N 3.34Å; D158-A160 PolarHBondContact O-N 2.79Å; A160-L164 CarbonylContact O-C 3.46Å; A160-L164 WeakPolarHBondContact O-CB 3.37Å; A160-L164 PolarHBondContact O-N 3.02Å; A160-S165 PolarHBondContact O-N 3.4Å; A160-E166 CarbonylContact C-O 3.45Å; A160-E166 PolarHBondContact O-N 2.63Å; A160-P168 HydrophobicContact CB-CB 4.03Å
161M96.7Very high95Very high3 Ų315.5 Ų15.52%0.0158%0.075CC..Iπ-helixtrans-73.4-50.9179.1-64.8-174.8-72.100112.1F157 D158 V159 S165 E166 P168 Y558 V561 F562 F565F157-M161 HydrophobicContact CD1-CE 3.7Å; F157-M161 HydrophobicContact CE1-CE 3.48Å; F157-M161 VanDerWaalsContact CE1-CE 3.48Å; F157-M161 HydrophobicContact CZ-CE 4.48Å; D158-M161 PolarHBondContact O-N 3.32Å; V159-M161 VanDerWaalsContact C-N 3.33Å; V159-M161 PolarHBondContact O-N 3.49Å; M161-S165 WeakPolarHBondContact O-CA 3.37Å; M161-S165 PolarHBondContact O-N 2.97Å; M161-E166 PolarHBondContact N-O 3.47Å; M161-P168 HydrophobicContact CG-CG 4.19Å; M161-P168 HydrophobicContact SD-CG 4.49Å; M161-Y558 HydrophobicContact CE-CD2 4.25Å; M161-Y558 HydrophobicContact CE-CG 4.5Å; M161-V561 HydrophobicContact CB-CG1 3.92Å; M161-F562 HydrophobicContact SD-CD2 4.34Å; M161-F565 HydrophobicContact CB-CB 4.18Å; M161-F565 HydrophobicContact CB-CD2 4.45Å; M161-F565 HydrophobicContact CB-CG 4.25Å; M161-F565 HydrophobicContact CG-CD1 4.48Å; M161-F565 HydrophobicContact CG-CG 4.35Å
162R95.4Very high95Very high90 Ų9015.4 Ų15.434%0.348%0.075SC..Iπ-helixtrans-69-41.7-169.3-171.5-173.8-61.9-81.74.5113.3D158 V561D158-R162 WeakPolarHBondContact O-CB 3.28Å; D158-R162 PolarHBondContact O-N 2.75Å; D158-R162 IonicContact OD1-CZ 3.48Å; D158-R162 VanDerWaalsContact OD1-CZ 3.26Å; D158-R162 IonicContact OD1-NE 3.3Å; D158-R162 PolarHBondContact OD1-NE 3.29Å; D158-R162 IonicContact OD1-NH2 3.94Å; D158-R162 PolarHBondContact OD1-NH2 2.72Å; D158-R162 IonicContact OD2-CZ 2.57Å; D158-R162 IonicContact OD2-NE 3.26Å; D158-R162 PolarHBondContact OD2-NE 3.21Å; D158-R162 IonicContact OD2-NH2 2.77Å; D158-R162 PolarHBondContact OD2-NH2 2.7Å; R162-V561 HydrophobicContact CB-CG1 3.7Å; R162-V561 HydrophobicContact CG-CG1 4.32Å; R162-V561 VanDerWaalsContact CZ-CG2 3.45Å
163F94.8Very high95Very high53 Ų5319.3 Ų19.323%0.2329%0.093CC..Iπ-helixtrans-117-30.8-167.6-64.3-61.4000113.5T59 P60 R126 V159T59-F163 HydrophobicContact CG2-CB 4.22Å; T59-F163 PolarHBondContact OG1-O 2.78Å; P60-F163 HydrophobicContact CG-CE1 4.4Å; R126-F163 VanDerWaalsContact CZ-CG 3.45Å; R126-F163 VanDerWaalsContact NH1-CD2 3.34Å; R126-F163 VanDerWaalsContact NH2-CE2 3.3Å; V159-F163 HydrophobicContact CB-CD2 4.21Å; V159-F163 HydrophobicContact CG1-CB 4.24Å; V159-F163 HydrophobicContact CG1-CD2 4.02Å; V159-F163 HydrophobicContact CG2-CD2 3.95Å; V159-F163 HydrophobicContact CG2-CE2 4.3Å; V159-F163 PolarHBondContact O-N 3.01Å
164L96.4Very high95.3Very high2 Ų221.4 Ų21.41%0.0110%0.102CC..Iπ-helixtrans-95.8-17.8178.2-51.3-179.4000111.8R126 V127 R128 V159 A160 E166 F583R126-L164 HydrophobicContact CB-CD2 4.42Å; R126-L164 WeakPolarHBondContact O-CD2 3.16Å; V127-L164 WeakPolarHBondContact O-CD1 3.39Å; R128-L164 HydrophobicContact CG-CD1 4.17Å; R128-L164 HydrophobicContact CG-CD2 4.01Å; R128-L164 HydrophobicContact CG-CG 4.5Å; V159-L164 HydrophobicContact CG1-CD1 4.49Å; V159-L164 HydrophobicContact CG1-CG 4.37Å; V159-L164 PolarHBondContact O-N 3.33Å; V159-L164 VanDerWaalsContact O-N 3.14Å; A160-L164 CarbonylContact O-C 3.46Å; A160-L164 WeakPolarHBondContact O-CB 3.37Å; A160-L164 PolarHBondContact O-N 3.02Å; L164-E166 VanDerWaalsContact C-N 3.25Å; L164-E166 HydrophobicContact CB-CB 4.49Å; L164-E166 HydrophobicContact CB-CG 3.92Å; L164-E166 WeakPolarHBondContact O-CG 3.49Å; L164-E166 PolarHBondContact O-N 2.74Å; L164-F583 WeakPolarHBondContact O-CE2 3.42Å; L164-F583 WeakPolarHBondContact O-CZ 2.96Å
165S96Very high95.8Very high9 Ų920.7 Ų20.76%0.06310%0.099CC..  trans55.342.6-174.7-53.40000112.3A160 M161A160-S165 PolarHBondContact O-N 3.4Å; M161-S165 WeakPolarHBondContact O-CA 3.37Å; M161-S165 PolarHBondContact O-N 2.97Å
166E95.7Very high96.4Very high2 Ų221.2 Ų21.21%0.00910%0.098CC..  trans-121.6147.4178.4-52.4-179.6173.600109.9R128 T129 A160 M161 L164 P168 R171 D576R128-E166 WeakPolarHBondContact CB-OE1 3.49Å; R128-E166 IonicContact CZ-OE1 3.9Å; R128-E166 IonicContact NE-OE1 3.94Å; R128-E166 PolarHBondContact NE-OE1 2.85Å; R128-E166 IonicContact NH2-OE1 3.21Å; R128-E166 PolarHBondContact NH2-OE1 3.17Å; T129-E166 VanDerWaalsContact CB-OE2 3.26Å; T129-E166 WeakPolarHBondContact CB-OE2 3.33Å; T129-E166 PolarHBondContact N-OE2 2.83Å; T129-E166 PolarHBondContact OG1-OE2 3.22Å; A160-E166 CarbonylContact C-O 3.45Å; A160-E166 PolarHBondContact O-N 2.63Å; M161-E166 PolarHBondContact N-O 3.47Å; L164-E166 VanDerWaalsContact C-N 3.25Å; L164-E166 HydrophobicContact CB-CB 4.49Å; L164-E166 HydrophobicContact CB-CG 3.92Å; L164-E166 WeakPolarHBondContact O-CG 3.49Å; L164-E166 PolarHBondContact O-N 2.74Å; E166-P168 WeakPolarHBondContact O-CD 3.18Å; E166-R171 IonicContact OE2-CZ 2.74Å; E166-R171 IonicContact OE2-NH2 3.42Å; E166-R171 PolarHBondContact OE2-NH2 2.83Å; E166-D576 HydrophobicContact CB-CB 4.45Å; E166-D576 HydrophobicContact CG-CB 3.96Å
167C96.3Very high96.7Very high30 Ų3024.8 Ų24.820%0.20313%0.128CC..  trans-77.8120.3175.7177.90000110.4W169 K170 R171 F565C167-W169 VanDerWaalsContact C-N 3.26Å; C167-W169 PolarHBondContact O-N 2.9Å; C167-K170 HydrophobicContact CB-CB 3.9Å; C167-K170 PolarHBondContact O-N 3.09Å; C167-R171 PolarHBondContact O-N 3.28Å; C167-R171 VanDerWaalsContact O-N 3.11Å; C167-F565 HydrophobicContact CB-CZ 4.1Å
168P97.3Very high96.8Very high1 Ų127.6 Ų27.61%0.00614%0.143CC..Hα-helixtrans-65-30.9179.925.7-33.7000112.2W152 F157 A160 M161 E166 R171 L172W152-P168 HydrophobicContact CZ2-CB 3.9Å; W152-P168 WeakPolarHBondContact CZ2-O 3.37Å; W152-P168 PolarHBondContact NE1-O 2.81Å; F157-P168 HydrophobicContact CD1-CG 4.28Å; F157-P168 HydrophobicContact CD2-CB 3.85Å; F157-P168 HydrophobicContact CD2-CG 3.75Å; F157-P168 HydrophobicContact CE1-CG 4.22Å; F157-P168 HydrophobicContact CE2-CB 4.16Å; F157-P168 HydrophobicContact CE2-CG 3.68Å; F157-P168 HydrophobicContact CG-CB 4.28Å; F157-P168 HydrophobicContact CG-CG 4.06Å; F157-P168 HydrophobicContact CZ-CG 3.93Å; A160-P168 HydrophobicContact CB-CB 4.03Å; M161-P168 HydrophobicContact CG-CG 4.19Å; M161-P168 HydrophobicContact SD-CG 4.49Å; E166-P168 WeakPolarHBondContact O-CD 3.18Å; P168-R171 WeakPolarHBondContact O-CB 3.4Å; P168-R171 PolarHBondContact O-N 3.13Å; P168-L172 PolarHBondContact O-N 3.39Å
169W98Very high97Very high2 Ų227.3 Ų27.31%0.00814%0.141CC..Hα-helixtrans-69.5-44.1177.6-58.199.2000112.2W152 F157 C167 R171 L172 Q173 F207 V210 A211 N214 E550 M553 S554W152-W169 AromaticContact CH2-CD2 3.69Å; W152-W169 HydrophobicContact CH2-CD2 3.69Å; W152-W169 AromaticContact CH2-CE2 3.93Å; W152-W169 AromaticContact CH2-CE3 3.45Å; W152-W169 HydrophobicContact CH2-CE3 3.45Å; W152-W169 VanDerWaalsContact CH2-CE3 3.45Å; W152-W169 HydrophobicContact CH2-CG 4.48Å; W152-W169 AromaticContact CH2-CH2 3.72Å; W152-W169 HydrophobicContact CH2-CH2 3.72Å; W152-W169 AromaticContact CH2-CZ2 3.95Å; W152-W169 HydrophobicContact CH2-CZ2 3.95Å; W152-W169 AromaticContact CH2-CZ3 3.46Å; W152-W169 HydrophobicContact CH2-CZ3 3.46Å; W152-W169 VanDerWaalsContact CH2-CZ3 3.46Å; W152-W169 AromaticContact CZ2-CD2 3.99Å; W152-W169 HydrophobicContact CZ2-CD2 3.99Å; W152-W169 AromaticContact CZ2-CE3 3.97Å; W152-W169 HydrophobicContact CZ2-CE3 3.97Å; W152-W169 HydrophobicContact CZ2-CG 4.34Å; W152-W169 HydrophobicContact CZ2-CZ3 4.41Å; W152-W169 HydrophobicContact CZ3-CE3 4.43Å; W152-W169 HydrophobicContact CZ3-CH2 4.22Å; W152-W169 HydrophobicContact CZ3-CZ3 4.07Å; F157-W169 HydrophobicContact CE2-CD2 4.31Å; F157-W169 AromaticContact CE2-CE2 3.54Å; F157-W169 HydrophobicContact CE2-CH2 4.48Å; F157-W169 AromaticContact CE2-CZ2 3.63Å; F157-W169 HydrophobicContact CE2-CZ2 3.63Å; F157-W169 AromaticContact CE2-NE1 3.51Å; F157-W169 AromaticContact CZ-CE2 3.73Å; F157-W169 AromaticContact CZ-CZ2 3.83Å; F157-W169 HydrophobicContact CZ-CZ2 3.83Å; F157-W169 AromaticContact CZ-NE1 3.35Å; F157-W169 VanDerWaalsContact CZ-NE1 3.35Å; C167-W169 VanDerWaalsContact C-N 3.26Å; C167-W169 PolarHBondContact O-N 2.9Å; W169-R171 VanDerWaalsContact C-N 3.27Å; W169-R171 PolarHBondContact O-N 2.9Å; W169-L172 WeakPolarHBondContact O-CB 3.5Å; W169-L172 PolarHBondContact O-N 2.89Å; W169-L172 VanDerWaalsContact O-N 3.07Å; W169-Q173 WeakPolarHBondContact O-CG 3.32Å; W169-Q173 PolarHBondContact O-N 2.95Å; W169-F207 HydrophobicContact CH2-CD2 4.25Å; W169-F207 AromaticContact CH2-CE2 3.88Å; W169-F207 HydrophobicContact CH2-CE2 3.88Å; W169-F207 HydrophobicContact CH2-CZ 4.23Å; W169-F207 HydrophobicContact CZ2-CD2 4.25Å; W169-F207 AromaticContact CZ2-CE2 3.78Å; W169-F207 HydrophobicContact CZ2-CE2 3.78Å; W169-F207 HydrophobicContact CZ2-CZ 4.45Å; W169-V210 HydrophobicContact CE3-CG1 4.22Å; W169-V210 HydrophobicContact CH2-CB 4.14Å; W169-V210 HydrophobicContact CH2-CG1 3.74Å; W169-V210 HydrophobicContact CZ2-CG1 4.39Å; W169-V210 HydrophobicContact CZ3-CB 4.28Å; W169-V210 HydrophobicContact CZ3-CG1 3.63Å; W169-A211 HydrophobicContact CZ3-CB 4.32Å; W169-N214 HydrophobicContact CE3-CB 4.27Å; W169-E550 HydrophobicContact CB-CB 3.93Å; W169-E550 HydrophobicContact CB-CG 3.79Å; W169-E550 HydrophobicContact CD2-CB 3.8Å; W169-E550 HydrophobicContact CD2-CG 3.69Å; W169-E550 HydrophobicContact CE3-CB 4.49Å; W169-E550 HydrophobicContact CE3-CG 3.9Å; W169-E550 HydrophobicContact CG-CB 3.52Å; W169-E550 HydrophobicContact CG-CG 3.66Å; W169-E550 PolarHBondContact NE1-O 2.96Å; W169-M553 HydrophobicContact CZ2-CB 3.95Å; W169-S554 PolarHBondContact NE1-OG 3.12Å
170K96.7Very high97.2Very high76 Ų7629.4 Ų29.433%0.3316%0.155SC..Hα-helixtrans-59.7-40.7173.8-172.8-178.6174.5-165.70110.9C167 L172 Q173 E174 D576C167-K170 HydrophobicContact CB-CB 3.9Å; C167-K170 PolarHBondContact O-N 3.09Å; K170-L172 PolarHBondContact O-N 2.82Å; K170-Q173 PolarHBondContact O-N 3.46Å; K170-E174 WeakPolarHBondContact CE-OE1 3.42Å; K170-E174 HydrophobicContact CG-CG 4.17Å; K170-E174 IonicContact NZ-OE1 3.38Å; K170-E174 WeakPolarHBondContact O-CB 3.41Å; K170-E174 VanDerWaalsContact O-CG 3.27Å; K170-E174 WeakPolarHBondContact O-CG 3.37Å; K170-E174 PolarHBondContact O-N 3.37Å; K170-D576 IonicContact NZ-OD2 3.34Å; K170-D576 PolarHBondContact NZ-OD2 3.36Å
171R97.8Very high97.2Very high5 Ų529.5 Ų29.52%0.01916%0.155CC..Hα-helixtrans-55.5-50.2171.7176.7-175.4-63.7-161.8-2.5111.1V127 T129 E166 C167 P168 W169 Q173 E174 L175V127-R171 PolarHBondContact O-NH1 3.25Å; V127-R171 PolarHBondContact O-NH2 2.83Å; T129-R171 HydrophobicContact CG2-CB 3.96Å; T129-R171 HydrophobicContact CG2-CG 3.98Å; T129-R171 PolarHBondContact OG1-NE 3.37Å; T129-R171 PolarHBondContact OG1-NH2 2.86Å; E166-R171 IonicContact OE2-CZ 2.74Å; E166-R171 IonicContact OE2-NH2 3.42Å; E166-R171 PolarHBondContact OE2-NH2 2.83Å; C167-R171 PolarHBondContact O-N 3.28Å; C167-R171 VanDerWaalsContact O-N 3.11Å; P168-R171 WeakPolarHBondContact O-CB 3.4Å; P168-R171 PolarHBondContact O-N 3.13Å; W169-R171 VanDerWaalsContact C-N 3.27Å; W169-R171 PolarHBondContact O-N 2.9Å; R171-Q173 PolarHBondContact O-N 3.06Å; R171-E174 PolarHBondContact O-N 3.12Å; R171-L175 HydrophobicContact CG-CD1 3.83Å; R171-L175 HydrophobicContact CG-CG 4.33Å; R171-L175 WeakPolarHBondContact O-CB 3.4Å; R171-L175 WeakPolarHBondContact O-CG 3.35Å; R171-L175 PolarHBondContact O-N 3.03Å
172L98.5Very high97.3Very high0 Ų029.4 Ų29.40%016%0.155CC..Hα-helixtrans-58.2-50178.8176.959.1000111.7W152 P168 W169 K170 L175 R176 F184 N214 M216W152-L172 HydrophobicContact CD2-CB 4.5Å; W152-L172 HydrophobicContact CD2-CD2 4.23Å; W152-L172 HydrophobicContact CE3-CD2 4.31Å; W152-L172 HydrophobicContact CH2-CD2 4.29Å; W152-L172 HydrophobicContact CZ2-CB 4.23Å; W152-L172 HydrophobicContact CZ2-CD2 4.23Å; W152-L172 HydrophobicContact CZ3-CD2 4.34Å; P168-L172 PolarHBondContact O-N 3.39Å; W169-L172 WeakPolarHBondContact O-CB 3.5Å; W169-L172 PolarHBondContact O-N 2.89Å; W169-L172 VanDerWaalsContact O-N 3.07Å; K170-L172 PolarHBondContact O-N 2.82Å; L172-L175 PolarHBondContact O-N 2.86Å; L172-R176 VanDerWaalsContact O-CB 3.24Å; L172-R176 WeakPolarHBondContact O-CB 3.4Å; L172-R176 PolarHBondContact O-N 3.14Å; L172-F184 HydrophobicContact CD1-CD2 3.68Å; L172-F184 HydrophobicContact CD1-CE2 4.18Å; L172-N214 HydrophobicContact CD2-CB 3.82Å; L172-N214 HydrophobicContact CG-CB 4.48Å; L172-M216 HydrophobicContact CD1-CE 3.76Å; L172-M216 HydrophobicContact CD2-CE 4.36Å
173Q98.3Very high97.5Very high84 Ų8425.1 Ų25.139%0.39314%0.138SC..Hα-helixtrans-61-46.6-179.6-67.7167.2-12.700112.4W169 K170 R171 R176 A177 N214W169-Q173 WeakPolarHBondContact O-CG 3.32Å; W169-Q173 PolarHBondContact O-N 2.95Å; K170-Q173 PolarHBondContact O-N 3.46Å; R171-Q173 PolarHBondContact O-N 3.06Å; Q173-R176 PolarHBondContact O-N 3.46Å; Q173-A177 PolarHBondContact O-N 2.89Å; Q173-A177 VanDerWaalsContact O-N 3.07Å; Q173-N214 WeakPolarHBondContact CG-OD1 3.43Å; Q173-N214 PolarHBondContact NE2-OD1 2.89Å
174E97.3Very high97.7Very high43 Ų4322.6 Ų22.620%0.20113%0.127CC..Hα-helixtrans-67.1-42.5-179.3-71.4-175.6150.100111.7K133 K170 R171 R176 A177 L178K133-E174 HydrophobicContact CD-CB 4.13Å; K133-E174 WeakPolarHBondContact CD-OE2 3.45Å; K133-E174 VanDerWaalsContact CE-OE2 3.29Å; K133-E174 WeakPolarHBondContact CE-OE2 3.14Å; K133-E174 IonicContact NZ-OE1 2.81Å; K133-E174 PolarHBondContact NZ-OE1 3.02Å; K133-E174 VanDerWaalsContact NZ-OE1 3.09Å; K133-E174 IonicContact NZ-OE2 3.36Å; K133-E174 PolarHBondContact NZ-OE2 3.41Å; K170-E174 WeakPolarHBondContact CE-OE1 3.42Å; K170-E174 HydrophobicContact CG-CG 4.17Å; K170-E174 IonicContact NZ-OE1 3.38Å; K170-E174 WeakPolarHBondContact O-CB 3.41Å; K170-E174 VanDerWaalsContact O-CG 3.27Å; K170-E174 WeakPolarHBondContact O-CG 3.37Å; K170-E174 PolarHBondContact O-N 3.37Å; R171-E174 PolarHBondContact O-N 3.12Å; E174-R176 VanDerWaalsContact C-N 3.32Å; E174-A177 PolarHBondContact O-N 2.85Å; E174-L178 WeakPolarHBondContact O-CG 3.43Å; E174-L178 PolarHBondContact O-N 2.69Å
175L98.4Very high97.8Very high0 Ų022.5 Ų22.50%013%0.127CC..Hα-helixtrans-64.5-39173.9-67.1-179.5000111.1F115 L132 K133 S136 N151 R171 L172 A177 L178 I179 F184F115-L175 HydrophobicContact CD2-CD1 4.11Å; F115-L175 HydrophobicContact CE2-CD1 4.46Å; F115-L175 HydrophobicContact CE2-CD2 4.06Å; L132-L175 HydrophobicContact CB-CD1 4.48Å; L132-L175 HydrophobicContact CB-CD2 3.94Å; L132-L175 HydrophobicContact CD1-CD1 4.49Å; K133-L175 HydrophobicContact CG-CD2 4.04Å; S136-L175 WeakPolarHBondContact OG-CD2 3.4Å; N151-L175 HydrophobicContact CB-CD1 4.46Å; R171-L175 HydrophobicContact CG-CD1 3.83Å; R171-L175 HydrophobicContact CG-CG 4.33Å; R171-L175 WeakPolarHBondContact O-CB 3.4Å; R171-L175 WeakPolarHBondContact O-CG 3.35Å; R171-L175 PolarHBondContact O-N 3.03Å; L172-L175 PolarHBondContact O-N 2.86Å; L175-A177 VanDerWaalsContact C-N 3.29Å; L175-A177 PolarHBondContact O-N 3Å; L175-L178 PolarHBondContact O-N 3.43Å; L175-I179 WeakPolarHBondContact O-CA 3.35Å; L175-I179 PolarHBondContact O-N 3.46Å; L175-F184 HydrophobicContact CB-CE2 3.93Å; L175-F184 HydrophobicContact CB-CZ 3.91Å; L175-F184 WeakPolarHBondContact O-CZ 3.45Å
176R98.4Very high97.9Very high22 Ų2222 Ų228%0.08312%0.124CC..Hα-helixtrans-62-40.5-179.6179.269.6-74.5162.22111.4R87 L172 Q173 E174 I179 V182 F184 G215 D217R87-R176 VanDerWaalsContact CD-NH1 3.28Å; L172-R176 VanDerWaalsContact O-CB 3.24Å; L172-R176 WeakPolarHBondContact O-CB 3.4Å; L172-R176 PolarHBondContact O-N 3.14Å; Q173-R176 PolarHBondContact O-N 3.46Å; E174-R176 VanDerWaalsContact C-N 3.32Å; R176-I179 VanDerWaalsContact NH2-C 3.28Å; R176-I179 PolarHBondContact NH2-O 2.83Å; R176-I179 PolarHBondContact O-N 2.84Å; R176-V182 PolarHBondContact NH1-O 3.17Å; R176-V182 PolarHBondContact NH2-O 3.35Å; R176-F184 VanDerWaalsContact CA-CE2 3.41Å; R176-F184 HydrophobicContact CB-CD2 4.37Å; R176-F184 HydrophobicContact CB-CE2 3.82Å; R176-F184 VanDerWaalsContact NH1-CG 3.25Å; R176-G215 WeakPolarHBondContact CD-O 3.32Å; R176-D217 IonicContact NH1-OD2 2.6Å; R176-D217 PolarHBondContact NH1-OD2 2.97Å
177A97.8Very high98Very high81 Ų8122 Ų2267%0.66912%0.124SC*.Hα-helixtrans-65.6-35.7177.400000112.9Q173 E174 L175Q173-A177 PolarHBondContact O-N 2.89Å; Q173-A177 VanDerWaalsContact O-N 3.07Å; E174-A177 PolarHBondContact O-N 2.85Å; L175-A177 VanDerWaalsContact C-N 3.29Å; L175-A177 PolarHBondContact O-N 3Å
178L97.6Very high98.1Very high61 Ų6120.6 Ų20.632%0.31911%0.114SC..Hα-helixtrans-82.1-23.7176.6-62.1169000113K133 P137 S140 E174 L175 P180K133-L178 HydrophobicContact CB-CD1 3.91Å; K133-L178 HydrophobicContact CG-CD1 3.91Å; P137-L178 HydrophobicContact CG-CD2 4.29Å; S140-L178 WeakPolarHBondContact CB-O 3.47Å; E174-L178 WeakPolarHBondContact O-CG 3.43Å; E174-L178 PolarHBondContact O-N 2.69Å; L175-L178 PolarHBondContact O-N 3.43Å; L178-P180 VanDerWaalsContact O-CD 3.31Å; L178-P180 WeakPolarHBondContact O-CD 3.43Å
179I98.5Very high97.9Very high0 Ų020.9 Ų20.90%012%0.115CC..  trans-83-1-175.8-7159.3000121.9F115 V139 L149 L175 R176 N181 V182 F184F115-I179 HydrophobicContact CE2-CD1 4.17Å; F115-I179 HydrophobicContact CZ-CD1 4.45Å; V139-I179 HydrophobicContact CB-CD1 4.42Å; V139-I179 HydrophobicContact CG1-CD1 4.46Å; L149-I179 HydrophobicContact CD2-CD1 3.6Å; L175-I179 WeakPolarHBondContact O-CA 3.35Å; L175-I179 PolarHBondContact O-N 3.46Å; R176-I179 VanDerWaalsContact NH2-C 3.28Å; R176-I179 PolarHBondContact NH2-O 2.83Å; R176-I179 PolarHBondContact O-N 2.84Å; I179-N181 PolarHBondContact O-N 3.05Å; I179-N181 PolarHBondContact O-OD1 3.36Å; I179-V182 HydrophobicContact CG2-CB 4.03Å; I179-V182 HydrophobicContact CG2-CG2 4.1Å; I179-V182 PolarHBondContact O-N 2.85Å; I179-F184 HydrophobicContact CB-CE1 3.87Å; I179-F184 HydrophobicContact CB-CZ 3.96Å; I179-F184 HydrophobicContact CD1-CE1 4.34Å; I179-F184 HydrophobicContact CD1-CZ 4.37Å; I179-F184 HydrophobicContact CG1-CZ 4.47Å; I179-F184 HydrophobicContact CG2-CE1 4.34Å
180P97.9Very high97.6Very high52 Ų5220.8 Ų20.834%0.33812%0.115SC..THydrogen-bonded Turntrans-58.9-16.8-135.526.8-38.1000118.1P82 R87 L178P82-P180 HydrophobicContact CG-CG 3.7Å; R87-P180 WeakPolarHBondContact CD-O 3.35Å; R87-P180 PolarHBondContact NH1-O 3.38Å; L178-P180 VanDerWaalsContact O-CD 3.31Å; L178-P180 WeakPolarHBondContact O-CD 3.43Å
181N98.3Very high97.3Very high4 Ų417.2 Ų17.22%0.02110%0.099CC..THydrogen-bonded Turntrans-102.7-17-17162.6-33.5000116.1P82 P83 G85 R87 S140 S144 I179P82-N181 HydrophobicContact CG-CB 4.47Å; P83-N181 WeakPolarHBondContact O-CB 3.46Å; P83-N181 PolarHBondContact O-ND2 3.46Å; G85-N181 CarbonylContact C-O 3.45Å; G85-N181 WeakPolarHBondContact CA-O 3.38Å; R87-N181 WeakPolarHBondContact CB-O 3.38Å; R87-N181 PolarHBondContact N-O 3.25Å; R87-N181 VanDerWaalsContact N-O 3.14Å; S140-N181 PolarHBondContact O-ND2 2.76Å; S140-N181 PolarHBondContact OG-OD1 3.17Å; S144-N181 WeakPolarHBondContact CB-ND2 3.33Å; I179-N181 PolarHBondContact O-N 3.05Å; I179-N181 PolarHBondContact O-OD1 3.36Å
182V98.7Very high96.9Very high0 Ų017.1 Ų17.10%010%0.099CC..SBendtrans-101.1132.5179.8-176.80000110.5L146 L149 R176 I179 F184L146-V182 HydrophobicContact CB-CG1 4.01Å; L149-V182 HydrophobicContact CB-CG1 4.14Å; R176-V182 PolarHBondContact NH1-O 3.17Å; R176-V182 PolarHBondContact NH2-O 3.35Å; I179-V182 HydrophobicContact CG2-CB 4.03Å; I179-V182 HydrophobicContact CG2-CG2 4.1Å; I179-V182 PolarHBondContact O-N 2.85Å; V182-F184 PolarHBondContact O-N 2.67Å
183P98.8Very high96.6Very high0 Ų017.1 Ų17.10%010%0.099CC..PPolyproline II helixtrans-59.3135.9176.8-25.235.7000111.4F86 R87 F98 F147 S148 L149 D217 I218F86-P183 HydrophobicContact CB-CG 3.89Å; R87-P183 HydrophobicContact CB-CG 4.03Å; F98-P183 HydrophobicContact CE2-CG 4.02Å; F98-P183 HydrophobicContact CZ-CG 4.36Å; F147-P183 WeakPolarHBondContact O-CD 3.3Å; F147-P183 VanDerWaalsContact O-CG 3.26Å; F147-P183 WeakPolarHBondContact O-CG 3.47Å; S148-P183 CarbonylContact C-O 3.58Å; S148-P183 VanDerWaalsContact CA-O 3.27Å; S148-P183 WeakPolarHBondContact CA-O 3.34Å; S148-P183 WeakPolarHBondContact CB-O 3.47Å; L149-P183 PolarHBondContact N-O 3.15Å; P183-D217 HydrophobicContact CB-CB 4.18Å; P183-I218 HydrophobicContact CB-CD1 3.92Å; P183-I218 HydrophobicContact CB-CG1 4.24Å
184F98.9Very high96.3Very high0 Ų013.3 Ų13.30%08%0.082CC..EExtended strand (participates in β ladder)trans-90.4133.6172.2-78.40.6000111L149 N151 L172 L175 R176 I179 V182 M216 D217 I218L149-F184 HydrophobicContact CB-CD1 4.4Å; L149-F184 HydrophobicContact CD2-CE1 4.01Å; N151-F184 WeakPolarHBondContact ND2-CD1 3.43Å; N151-F184 WeakPolarHBondContact ND2-CD2 3.17Å; N151-F184 WeakPolarHBondContact ND2-CE1 2.95Å; N151-F184 WeakPolarHBondContact ND2-CE2 3.36Å; N151-F184 WeakPolarHBondContact ND2-CG 3.26Å; N151-F184 WeakPolarHBondContact ND2-CZ 3.42Å; L172-F184 HydrophobicContact CD1-CD2 3.68Å; L172-F184 HydrophobicContact CD1-CE2 4.18Å; L175-F184 HydrophobicContact CB-CE2 3.93Å; L175-F184 HydrophobicContact CB-CZ 3.91Å; L175-F184 WeakPolarHBondContact O-CZ 3.45Å; R176-F184 VanDerWaalsContact CA-CE2 3.41Å; R176-F184 HydrophobicContact CB-CD2 4.37Å; R176-F184 HydrophobicContact CB-CE2 3.82Å; R176-F184 VanDerWaalsContact NH1-CG 3.25Å; I179-F184 HydrophobicContact CB-CE1 3.87Å; I179-F184 HydrophobicContact CB-CZ 3.96Å; I179-F184 HydrophobicContact CD1-CE1 4.34Å; I179-F184 HydrophobicContact CD1-CZ 4.37Å; I179-F184 HydrophobicContact CG1-CZ 4.47Å; I179-F184 HydrophobicContact CG2-CE1 4.34Å; V182-F184 PolarHBondContact O-N 2.67Å; F184-M216 HydrophobicContact CB-CE 4.33Å; F184-M216 HydrophobicContact CB-SD 4.13Å; F184-D217 PolarHBondContact N-OD2 2.86Å; F184-D217 CarbonylContact O-C 3.25Å; F184-D217 WeakPolarHBondContact O-CA 3.38Å; F184-D217 WeakPolarHBondContact O-CB 3.18Å; F184-D217 PolarHBondContact O-N 3.36Å; F184-I218 PolarHBondContact O-N 2.88Å
185Q98.9Very high95.8Very high0 Ų011.4 Ų11.40%07%0.073CC..EExtended strand (participates in β ladder)trans-119.1140.8-179.1-179.6156.6-24.900111.5M111 F147 S148 L149 E150 N151 M216 I218 R220 E246M111-Q185 HydrophobicContact SD-CG 4.2Å; M111-Q185 PolarHBondContact SD-NE2 3.33Å; M111-Q185 VanDerWaalsContact SD-NE2 3.41Å; F147-Q185 VanDerWaalsContact CE1-OE1 3.25Å; S148-Q185 PolarHBondContact OG-OE1 3.5Å; L149-Q185 PolarHBondContact O-N 3.43Å; E150-Q185 WeakPolarHBondContact CA-O 3.28Å; E150-Q185 HydrophobicContact CB-CB 4.39Å; E150-Q185 HydrophobicContact CG-CG 4.43Å; N151-Q185 PolarHBondContact N-O 2.81Å; N151-Q185 VanDerWaalsContact N-O 3.17Å; Q185-M216 VanDerWaalsContact C-SD 3.52Å; Q185-I218 WeakPolarHBondContact CA-O 3.46Å; Q185-I218 HydrophobicContact CB-CB 4.06Å; Q185-I218 HydrophobicContact CG-CB 4.06Å; Q185-I218 HydrophobicContact CG-CG2 4.14Å; Q185-R220 VanDerWaalsContact NE2-CZ 3.26Å; Q185-E246 PolarHBondContact NE2-OE2 2.93Å
186M98.6Very high94.8Very high0 Ų016 Ų160%09%0.091CC..EExtended strand (participates in β ladder)trans-125.6153171.668.5169.5-63.600112.5W152 L188 V194 F207 A211 M216 I218 F219 R220W152-M186 HydrophobicContact CB-CB 4.1Å; W152-M186 HydrophobicContact CE3-CE 4.38Å; W152-M186 HydrophobicContact CE3-SD 4.27Å; W152-M186 VanDerWaalsContact O-CA 3.28Å; W152-M186 WeakPolarHBondContact O-CA 3.5Å; W152-M186 WeakPolarHBondContact O-CB 3.39Å; M186-L188 HydrophobicContact CE-CB 4.22Å; M186-L188 HydrophobicContact CE-CD1 3.7Å; M186-L188 HydrophobicContact SD-CD1 4.38Å; M186-V194 HydrophobicContact CE-CG1 3.71Å; M186-F207 HydrophobicContact CE-CE1 3.89Å; M186-F207 HydrophobicContact CE-CZ 4.49Å; M186-F207 HydrophobicContact SD-CE1 4.35Å; M186-A211 HydrophobicContact SD-CB 4.5Å; M186-M216 HydrophobicContact CB-CE 3.78Å; M186-M216 HydrophobicContact CB-CG 4.32Å; M186-M216 HydrophobicContact CB-SD 3.65Å; M186-M216 HydrophobicContact CG-CE 4.24Å; M186-M216 HydrophobicContact CG-CG 3.74Å; M186-M216 HydrophobicContact CG-SD 3.7Å; M186-M216 PolarHBondContact N-SD 2.97Å; M186-M216 VanDerWaalsContact N-SD 3.43Å; M186-M216 HydrophobicContact SD-CG 3.89Å; M186-M216 HydrophobicContact SD-SD 4.45Å; M186-I218 PolarHBondContact N-O 2.84Å; M186-F219 HydrophobicContact CG-CD1 3.84Å; M186-F219 HydrophobicContact CG-CE1 4.25Å; M186-F219 HydrophobicContact CG-CG 4.43Å; M186-F219 HydrophobicContact SD-CD1 3.54Å; M186-F219 VanDerWaalsContact SD-CD1 3.54Å; M186-F219 HydrophobicContact SD-CE1 3.5Å; M186-F219 WeakPolarHBondContact SD-CE1 3.38Å; M186-R220 WeakPolarHBondContact O-CB 3.47Å; M186-R220 PolarHBondContact O-N 2.7Å
187L97.5Very high93.9Very high1 Ų119 Ų191%0.00511%0.112CC..EExtended strand (participates in β ladder)trans-88.1116.4166-172.465.2000109.6W152 G153 D154 R220 F222 K286W152-L187 PolarHBondContact O-N 3.16Å; G153-L187 WeakPolarHBondContact CA-O 3.49Å; D154-L187 HydrophobicContact CB-CB 4.29Å; D154-L187 HydrophobicContact CB-CD2 3.95Å; D154-L187 HydrophobicContact CB-CG 4.39Å; D154-L187 PolarHBondContact N-O 3.21Å; L187-R220 HydrophobicContact CD1-CB 4.3Å; L187-R220 HydrophobicContact CD1-CG 3.96Å; L187-F222 HydrophobicContact CD1-CD1 3.42Å; L187-F222 VanDerWaalsContact CD1-CD1 3.42Å; L187-F222 HydrophobicContact CD1-CE1 3.76Å; L187-F222 HydrophobicContact CD1-CG 4.19Å; L187-F222 HydrophobicContact CD2-CD1 4.34Å; L187-F222 HydrophobicContact CD2-CE1 3.85Å; L187-F222 HydrophobicContact CD2-CZ 4.28Å; L187-F222 HydrophobicContact CG-CD1 3.77Å; L187-F222 HydrophobicContact CG-CE1 3.54Å; L187-F222 HydrophobicContact CG-CZ 4.44Å; L187-K286 HydrophobicContact CD1-CD 4.23Å
188L97.2Very high93.2Very high0 Ų016 Ų160%09%0.085CC..EExtended strand (participates in β ladder)trans-112.8122-179.9-171.181000109.9M186 G190 A193 F207 F219 R220 V221 F222M186-L188 HydrophobicContact CE-CB 4.22Å; M186-L188 HydrophobicContact CE-CD1 3.7Å; M186-L188 HydrophobicContact SD-CD1 4.38Å; L188-G190 PolarHBondContact O-N 3.01Å; L188-A193 HydrophobicContact CD1-CB 3.92Å; L188-F207 HydrophobicContact CD1-CD1 4.14Å; L188-F207 HydrophobicContact CD1-CE1 4.15Å; L188-F219 HydrophobicContact CD2-CD1 4.23Å; L188-R220 PolarHBondContact N-O 2.9Å; L188-V221 HydrophobicContact CD2-CG2 4.06Å; L188-V221 WeakPolarHBondContact O-CA 3.41Å; L188-F222 VanDerWaalsContact O-CD1 3.3Å; L188-F222 WeakPolarHBondContact O-CD1 3.23Å; L188-F222 PolarHBondContact O-N 2.66Å
189R94.6Very high92.9Very high8 Ų813.8 Ų13.83%0.037%0.072CC..EExtended strand (participates in β ladder)trans-85.4107.4174.8-165.6173.489.8-151.13.6109.4A191 N192 A193 G195 Y196 F222 T453R189-A191 PolarHBondContact O-N 3.02Å; R189-N192 HydrophobicContact CB-CB 4.2Å; R189-N192 HydrophobicContact CG-CB 4.22Å; R189-N192 VanDerWaalsContact CZ-CB 3.49Å; R189-N192 PolarHBondContact NE-OD1 3.23Å; R189-N192 VanDerWaalsContact NH2-CB 3.27Å; R189-N192 PolarHBondContact NH2-ND2 3.21Å; R189-N192 VanDerWaalsContact NH2-ND2 3.17Å; R189-N192 PolarHBondContact NH2-OD1 2.81Å; R189-N192 CarbonylContact O-C 3.52Å; R189-N192 WeakPolarHBondContact O-CA 3.47Å; R189-N192 PolarHBondContact O-N 3.34Å; R189-A193 WeakPolarHBondContact CB-O 3.43Å; R189-A193 PolarHBondContact N-O 3.15Å; R189-A193 PolarHBondContact O-N 2.57Å; R189-G195 PolarHBondContact NH1-O 3.08Å; R189-G195 PolarHBondContact NH2-O 3.24Å; R189-Y196 PolarHBondContact NH2-O 3.47Å; R189-F222 CarbonylContact C-O 3.3Å; R189-F222 WeakPolarHBondContact CA-O 3.13Å; R189-F222 HydrophobicContact CB-CD1 4.45Å; R189-F222 HydrophobicContact CB-CE1 3.71Å; R189-F222 HydrophobicContact CB-CZ 3.97Å; R189-F222 HydrophobicContact CG-CE1 4.04Å; R189-F222 HydrophobicContact CG-CE2 4.36Å; R189-F222 HydrophobicContact CG-CZ 3.86Å; R189-T453 WeakPolarHBondContact CD-O 3.27Å
190G91.4Very high92.7Very high0 Ų014.4 Ų14.40%08%0.076CC..G310 helixtrans-12.8-93.4-173.700000116.4L188 N192 F222 N230L188-G190 PolarHBondContact O-N 3.01Å; G190-N192 PolarHBondContact O-N 2.91Å; G190-F222 PolarHBondContact N-O 3.27Å; G190-N230 CarbonylContact C-O 3.33Å; G190-N230 VanDerWaalsContact CA-O 3.25Å; G190-N230 WeakPolarHBondContact CA-O 3.21Å
191A89.1Confident92.6Very high0 Ų014.4 Ų14.40%07%0.074CC..G310 helixtrans-78.64.4-177.300000115.2R189 N230 L233R189-A191 PolarHBondContact O-N 3.02Å; A191-N230 HydrophobicContact CB-CB 3.96Å; A191-N230 PolarHBondContact N-O 2.76Å; A191-L233 HydrophobicContact CB-CD2 3.94Å
192N89.8Confident92.6Very high3 Ų316.4 Ų16.42%0.0168%0.084CC..G310 helixtrans-120.6-3.2-174.3-49.1105.7000113R189 G190 V194 G195 T197 N198 Y199R189-N192 HydrophobicContact CB-CB 4.2Å; R189-N192 HydrophobicContact CG-CB 4.22Å; R189-N192 VanDerWaalsContact CZ-CB 3.49Å; R189-N192 PolarHBondContact NE-OD1 3.23Å; R189-N192 VanDerWaalsContact NH2-CB 3.27Å; R189-N192 PolarHBondContact NH2-ND2 3.21Å; R189-N192 VanDerWaalsContact NH2-ND2 3.17Å; R189-N192 PolarHBondContact NH2-OD1 2.81Å; R189-N192 CarbonylContact O-C 3.52Å; R189-N192 WeakPolarHBondContact O-CA 3.47Å; R189-N192 PolarHBondContact O-N 3.34Å; G190-N192 PolarHBondContact O-N 2.91Å; N192-V194 PolarHBondContact O-N 3.46Å; N192-G195 PolarHBondContact O-N 3.08Å; N192-T197 PolarHBondContact ND2-O 3.03Å; N192-N198 VanDerWaalsContact ND2-CA 3.35Å; N192-N198 WeakPolarHBondContact ND2-CA 3.33Å; N192-N198 PolarHBondContact ND2-N 3.48Å; N192-N198 PolarHBondContact ND2-OD1 3.26Å; N192-Y199 WeakPolarHBondContact O-CD2 3.45Å; N192-Y199 WeakPolarHBondContact O-CE2 3.32Å
193A92.4Very high92.5Very high1 Ų116.4 Ų16.41%0.0088%0.084CC..BIsolated β-bridgetrans46.6-104.1-169.600000112.6L188 R189 F207 M557L188-A193 HydrophobicContact CD1-CB 3.92Å; R189-A193 WeakPolarHBondContact CB-O 3.43Å; R189-A193 PolarHBondContact N-O 3.15Å; R189-A193 PolarHBondContact O-N 2.57Å; A193-F207 HydrophobicContact CB-CB 4.17Å; A193-F207 HydrophobicContact CB-CD1 3.77Å; A193-F207 HydrophobicContact CB-CD2 4.49Å; A193-F207 HydrophobicContact CB-CE1 4.35Å; A193-F207 HydrophobicContact CB-CG 3.86Å; A193-M557 HydrophobicContact CB-SD 4.35Å
194V91.8Very high92.4Very high4 Ų416.4 Ų16.42%0.0248%0.084CC..THydrogen-bonded Turntrans-111.85.7179.3-65.10000113.5F157 M186 N192 F207 M557 Y558F157-V194 HydrophobicContact CB-CB 4.1Å; F157-V194 HydrophobicContact CB-CG1 4.45Å; F157-V194 HydrophobicContact CB-CG2 4.17Å; F157-V194 HydrophobicContact CD1-CG2 3.89Å; F157-V194 HydrophobicContact CD2-CG2 4.21Å; F157-V194 HydrophobicContact CE1-CG2 4.31Å; F157-V194 HydrophobicContact CG-CB 4.29Å; F157-V194 HydrophobicContact CG-CG2 3.82Å; M186-V194 HydrophobicContact CE-CG1 3.71Å; N192-V194 PolarHBondContact O-N 3.46Å; V194-F207 HydrophobicContact CB-CZ 4.14Å; V194-F207 HydrophobicContact CG1-CE1 3.78Å; V194-F207 HydrophobicContact CG1-CE2 4.29Å; V194-F207 HydrophobicContact CG1-CZ 3.45Å; V194-F207 VanDerWaalsContact CG1-CZ 3.45Å; V194-F207 HydrophobicContact CG2-CD2 4.29Å; V194-F207 HydrophobicContact CG2-CE1 4.38Å; V194-F207 HydrophobicContact CG2-CE2 3.47Å; V194-F207 VanDerWaalsContact CG2-CE2 3.47Å; V194-F207 HydrophobicContact CG2-CZ 3.54Å; V194-M557 HydrophobicContact CG2-CG 4.37Å; V194-Y558 HydrophobicContact CG2-CE2 4.21Å; V194-Y558 PolarHBondContact O-OH 2.91Å
195G86.3Confident92.4Very high2 Ų219.5 Ų19.52%0.02110%0.096CC..SBendtrans-90.5-179.8-172.100000116.3R189 N192 Y199 Y558R189-G195 PolarHBondContact NH1-O 3.08Å; R189-G195 PolarHBondContact NH2-O 3.24Å; N192-G195 PolarHBondContact O-N 3.08Å; G195-Y199 VanDerWaalsContact CA-OH 3.23Å; G195-Y199 WeakPolarHBondContact CA-OH 3.32Å; G195-Y558 WeakPolarHBondContact CA-OH 3.42Å
196Y78.7Confident92.4Very high96 Ų9622.3 Ų22.338%0.37611%0.109SC..SBendtrans-101.8-15.7173.6-62.4-61000114.3D158 R189 T453 Y558D158-Y196 HydrophobicContact CB-CE2 4.43Å; R189-Y196 PolarHBondContact NH2-O 3.47Å; Y196-T453 HydrophobicContact CD1-CG2 4.4Å; Y196-T453 HydrophobicContact CE1-CG2 3.98Å; Y196-Y558 AromaticContact CD2-CE1 3.75Å; Y196-Y558 HydrophobicContact CD2-CE1 3.75Å; Y196-Y558 AromaticContact CE2-CE1 3.82Å; Y196-Y558 HydrophobicContact CE2-CE1 3.82Å
197T78.4Confident92.4Very high86 Ų8622.3 Ų22.353%0.52811%0.109SC..SBendtrans-113169.2178.463.10000111.4N192 Y199N192-T197 PolarHBondContact ND2-O 3.03Å; T197-Y199 VanDerWaalsContact O-CE2 3.27Å; T197-Y199 WeakPolarHBondContact O-CE2 3.39Å
198N83.7Confident92.4Very high18 Ų1822.3 Ų22.310%0.09611%0.109CC..  trans-76144168.5-84.9-62.2000111N192 Y496 P523N192-N198 VanDerWaalsContact ND2-CA 3.35Å; N192-N198 WeakPolarHBondContact ND2-CA 3.33Å; N192-N198 PolarHBondContact ND2-N 3.48Å; N192-N198 PolarHBondContact ND2-OD1 3.26Å; N198-Y496 PolarHBondContact ND2-O 2.77Å; N198-P523 HydrophobicContact CB-CB 3.92Å; N198-P523 WeakPolarHBondContact ND2-CB 3.49Å; N198-P523 WeakPolarHBondContact ND2-CG 3.37Å
199Y91.4Very high92.5Very high14 Ų1425.9 Ų25.96%0.05513%0.125CC..  trans-115.7157.3178.8-58.7-68.8000110.4N192 G195 T197 G524 M557N192-Y199 WeakPolarHBondContact O-CD2 3.45Å; N192-Y199 WeakPolarHBondContact O-CE2 3.32Å; G195-Y199 VanDerWaalsContact CA-OH 3.23Å; G195-Y199 WeakPolarHBondContact CA-OH 3.32Å; T197-Y199 VanDerWaalsContact O-CE2 3.27Å; T197-Y199 WeakPolarHBondContact O-CE2 3.39Å; Y199-G524 WeakPolarHBondContact O-CA 3.43Å; Y199-M557 HydrophobicContact CD1-SD 4.35Å; Y199-M557 HydrophobicContact CD2-CE 4.45Å; Y199-M557 HydrophobicContact CD2-SD 3.76Å; Y199-M557 HydrophobicContact CE1-SD 4.18Å; Y199-M557 HydrophobicContact CE2-SD 3.55Å; Y199-M557 VanDerWaalsContact CE2-SD 3.55Å; Y199-M557 HydrophobicContact CG-CE 4.48Å; Y199-M557 HydrophobicContact CG-SD 4.17Å; Y199-M557 PolarHBondContact OH-O 3.05Å
200P94.8Very high92.7Very high13 Ų1325.5 Ų25.58%0.08412%0.124CC..  trans-56.8145.8163.4-17.229.2000109.9N202 A203 L527 S528 M530P200-N202 VanDerWaalsContact C-N 3.25Å; P200-N202 WeakPolarHBondContact CB-OD1 3.34Å; P200-N202 PolarHBondContact O-N 3.43Å; P200-A203 WeakPolarHBondContact O-CB 3.38Å; P200-A203 PolarHBondContact O-N 2.96Å; P200-L527 HydrophobicContact CB-CB 4.21Å; P200-L527 HydrophobicContact CG-CB 3.86Å; P200-L527 HydrophobicContact CG-CD1 4.37Å; P200-S528 WeakPolarHBondContact CB-O 3.09Å; P200-S528 WeakPolarHBondContact CG-O 3.41Å; P200-M530 HydrophobicContact CG-CB 4.48Å
201D96.4Very high93Very high52 Ų5225.5 Ų25.528%0.27812%0.124SC..Hα-helixtrans-54.1-43.4-173.2-64.94.4000112.1A203 V204 Y205 L233 R522D201-A203 PolarHBondContact O-N 2.94Å; D201-A203 VanDerWaalsContact O-N 3.08Å; D201-V204 WeakPolarHBondContact O-CA 3.47Å; D201-V204 WeakPolarHBondContact O-CB 3.29Å; D201-V204 PolarHBondContact O-N 3.44Å; D201-Y205 HydrophobicContact CB-CD2 4.46Å; D201-Y205 HydrophobicContact CB-CE2 4.43Å; D201-Y205 VanDerWaalsContact O-CD2 3.29Å; D201-Y205 WeakPolarHBondContact O-CD2 3.39Å; D201-Y205 PolarHBondContact O-N 3.11Å; D201-L233 HydrophobicContact CB-CD1 3.99Å; D201-L233 HydrophobicContact CB-CD2 4.43Å; D201-R522 IonicContact OD1-CZ 2.78Å; D201-R522 IonicContact OD1-NH1 3.9Å; D201-R522 PolarHBondContact OD1-NH1 3.21Å; D201-R522 IonicContact OD1-NH2 3.14Å; D201-R522 PolarHBondContact OD1-NH2 3.44Å; D201-R522 IonicContact OD2-CZ 2.95Å; D201-R522 IonicContact OD2-NH1 2.72Å; D201-R522 IonicContact OD2-NH2 2.99Å; D201-R522 PolarHBondContact OD2-NH2 3.16Å
202N97.2Very high93.5Very high46 Ų4627.7 Ų27.725%0.24613%0.134CC..Hα-helixtrans-59.1-25.9-178.574.3-41.3000113.5P200 K206 P529 M530 F532P200-N202 VanDerWaalsContact C-N 3.25Å; P200-N202 WeakPolarHBondContact CB-OD1 3.34Å; P200-N202 PolarHBondContact O-N 3.43Å; N202-K206 VanDerWaalsContact O-CB 3.29Å; N202-K206 WeakPolarHBondContact O-CB 3.48Å; N202-K206 PolarHBondContact O-N 2.87Å; N202-P529 WeakPolarHBondContact OD1-CA 3.06Å; N202-M530 PolarHBondContact ND2-N 3.43Å; N202-M530 PolarHBondContact ND2-O 3.33Å; N202-M530 PolarHBondContact OD1-N 3.36Å; N202-F532 HydrophobicContact CB-CE2 4.46Å; N202-F532 VanDerWaalsContact ND2-CE2 3.29Å; N202-F532 WeakPolarHBondContact ND2-CE2 3.33Å
203A97Very high93.8Very high0 Ų033.8 Ų33.80%016%0.162CC..Hα-helixtrans-73.7-34.3173.500000112.9P200 D201 F207 M530 F532 M557P200-A203 WeakPolarHBondContact O-CB 3.38Å; P200-A203 PolarHBondContact O-N 2.96Å; D201-A203 PolarHBondContact O-N 2.94Å; D201-A203 VanDerWaalsContact O-N 3.08Å; A203-F207 VanDerWaalsContact O-CB 3.29Å; A203-F207 WeakPolarHBondContact O-CB 3.36Å; A203-F207 PolarHBondContact O-N 3.11Å; A203-M530 HydrophobicContact CB-CE 4.5Å; A203-F532 HydrophobicContact CB-CE1 4.45Å; A203-F532 HydrophobicContact CB-CZ 4.18Å; A203-M557 HydrophobicContact CB-CE 3.8Å; A203-M557 WeakPolarHBondContact O-CE 3.47Å
204V97.3Very high94.1Very high0 Ų034.5 Ų34.50%017%0.166CC..Hα-helixtrans-69.5-44.8174.3-175.90000110.5D201 F207 C208 L233 A237D201-V204 WeakPolarHBondContact O-CA 3.47Å; D201-V204 WeakPolarHBondContact O-CB 3.29Å; D201-V204 PolarHBondContact O-N 3.44Å; V204-F207 PolarHBondContact O-N 2.95Å; V204-C208 PolarHBondContact O-N 3.01Å; V204-C208 VanDerWaalsContact O-N 3.12Å; V204-C208 PolarHBondContact O-SG 3.05Å; V204-L233 HydrophobicContact CG2-CD2 4.33Å; V204-A237 HydrophobicContact CG1-CB 3.96Å
205Y98.4Very high94.4Very high65 Ų6534.8 Ų34.826%0.25517%0.169SC..Hα-helixtrans-57.9-52.8173.7-81.3-86.7000111.6D201 F207 C208 E209 L233 E236 A237D201-Y205 HydrophobicContact CB-CD2 4.46Å; D201-Y205 HydrophobicContact CB-CE2 4.43Å; D201-Y205 VanDerWaalsContact O-CD2 3.29Å; D201-Y205 WeakPolarHBondContact O-CD2 3.39Å; D201-Y205 PolarHBondContact O-N 3.11Å; Y205-F207 VanDerWaalsContact C-N 3.26Å; Y205-F207 PolarHBondContact O-N 3.22Å; Y205-C208 PolarHBondContact O-N 3.38Å; Y205-C208 VanDerWaalsContact O-N 3.16Å; Y205-E209 PolarHBondContact O-N 2.88Å; Y205-L233 HydrophobicContact CD2-CD1 4.34Å; Y205-L233 HydrophobicContact CE2-CD1 3.57Å; Y205-E236 HydrophobicContact CE1-CG 4.39Å; Y205-E236 WeakPolarHBondContact OH-CG 3.33Å; Y205-E236 PolarHBondContact OH-OE1 2.91Å; Y205-E236 PolarHBondContact OH-OE2 3.34Å; Y205-A237 HydrophobicContact CD1-CB 3.97Å; Y205-A237 HydrophobicContact CD2-CB 4.41Å; Y205-A237 HydrophobicContact CE1-CB 4.16Å; Y205-A237 HydrophobicContact CG-CB 4.09Å
206K98.3Very high95Very high60 Ų6034.7 Ų34.726%0.26117%0.168SC..Hα-helixtrans-63.5-34.4-178.1-170.258-179.5175.70112.2N202 E209 V210 F532 M553N202-K206 VanDerWaalsContact O-CB 3.29Å; N202-K206 WeakPolarHBondContact O-CB 3.48Å; N202-K206 PolarHBondContact O-N 2.87Å; K206-E209 WeakPolarHBondContact CD-OE2 3.49Å; K206-E209 IonicContact NZ-OE1 2.93Å; K206-E209 PolarHBondContact NZ-OE1 3.4Å; K206-E209 IonicContact NZ-OE2 3.57Å; K206-E209 PolarHBondContact NZ-OE2 3.21Å; K206-V210 HydrophobicContact CD-CG2 4.23Å; K206-V210 HydrophobicContact CG-CG2 4.39Å; K206-V210 VanDerWaalsContact O-CG2 3.3Å; K206-V210 WeakPolarHBondContact O-CG2 3.47Å; K206-V210 PolarHBondContact O-N 3.41Å; K206-F532 HydrophobicContact CB-CE2 4.1Å; K206-F532 HydrophobicContact CB-CZ 3.92Å; K206-F532 HydrophobicContact CG-CE2 4.34Å; K206-F532 HydrophobicContact CG-CZ 4.33Å; K206-M553 HydrophobicContact CB-CE 4.43Å; K206-M553 HydrophobicContact CB-SD 3.94Å; K206-M553 HydrophobicContact CG-CG 4.44Å; K206-M553 HydrophobicContact CG-SD 3.52Å; K206-M553 VanDerWaalsContact CG-SD 3.52Å
207F98.3Very high96Very high0 Ų030.1 Ų30.10%015%0.15CC..Hα-helixtrans-62-47.6174.4-174.1-87.2000112.3W152 F157 W169 M186 L188 A193 V194 A203 V204 Y205 E209 V210 A211 M553 M557W152-F207 HydrophobicContact CH2-CZ 4.33Å; W152-F207 HydrophobicContact CZ3-CE1 4.33Å; W152-F207 AromaticContact CZ3-CZ 3.76Å; W152-F207 HydrophobicContact CZ3-CZ 3.76Å; F157-F207 HydrophobicContact CD2-CE2 4.41Å; F157-F207 HydrophobicContact CD2-CZ 4.35Å; F157-F207 AromaticContact CE2-CE2 3.92Å; F157-F207 HydrophobicContact CE2-CE2 3.92Å; F157-F207 HydrophobicContact CE2-CZ 4.22Å; F157-F207 HydrophobicContact CZ-CE2 4.16Å; W169-F207 HydrophobicContact CH2-CD2 4.25Å; W169-F207 AromaticContact CH2-CE2 3.88Å; W169-F207 HydrophobicContact CH2-CE2 3.88Å; W169-F207 HydrophobicContact CH2-CZ 4.23Å; W169-F207 HydrophobicContact CZ2-CD2 4.25Å; W169-F207 AromaticContact CZ2-CE2 3.78Å; W169-F207 HydrophobicContact CZ2-CE2 3.78Å; W169-F207 HydrophobicContact CZ2-CZ 4.45Å; M186-F207 HydrophobicContact CE-CE1 3.89Å; M186-F207 HydrophobicContact CE-CZ 4.49Å; M186-F207 HydrophobicContact SD-CE1 4.35Å; L188-F207 HydrophobicContact CD1-CD1 4.14Å; L188-F207 HydrophobicContact CD1-CE1 4.15Å; A193-F207 HydrophobicContact CB-CB 4.17Å; A193-F207 HydrophobicContact CB-CD1 3.77Å; A193-F207 HydrophobicContact CB-CD2 4.49Å; A193-F207 HydrophobicContact CB-CE1 4.35Å; A193-F207 HydrophobicContact CB-CG 3.86Å; V194-F207 HydrophobicContact CB-CZ 4.14Å; V194-F207 HydrophobicContact CG1-CE1 3.78Å; V194-F207 HydrophobicContact CG1-CE2 4.29Å; V194-F207 HydrophobicContact CG1-CZ 3.45Å; V194-F207 VanDerWaalsContact CG1-CZ 3.45Å; V194-F207 HydrophobicContact CG2-CD2 4.29Å; V194-F207 HydrophobicContact CG2-CE1 4.38Å; V194-F207 HydrophobicContact CG2-CE2 3.47Å; V194-F207 VanDerWaalsContact CG2-CE2 3.47Å; V194-F207 HydrophobicContact CG2-CZ 3.54Å; A203-F207 VanDerWaalsContact O-CB 3.29Å; A203-F207 WeakPolarHBondContact O-CB 3.36Å; A203-F207 PolarHBondContact O-N 3.11Å; V204-F207 PolarHBondContact O-N 2.95Å; Y205-F207 VanDerWaalsContact C-N 3.26Å; Y205-F207 PolarHBondContact O-N 3.22Å; F207-E209 VanDerWaalsContact C-N 3.34Å; F207-V210 PolarHBondContact O-N 3.39Å; F207-A211 HydrophobicContact CE1-CB 4.33Å; F207-A211 VanDerWaalsContact O-CB 3.26Å; F207-A211 WeakPolarHBondContact O-CB 3.4Å; F207-A211 PolarHBondContact O-N 3.04Å; F207-M553 HydrophobicContact CB-CE 3.71Å; F207-M553 HydrophobicContact CD2-CE 4.12Å; F207-M553 HydrophobicContact CG-CE 4.43Å; F207-M557 HydrophobicContact CB-CE 4.12Å; F207-M557 HydrophobicContact CD2-CE 4.37Å; F207-M557 HydrophobicContact CD2-CG 4.02Å; F207-M557 HydrophobicContact CE2-CG 4.42Å
208C98.5Very high96.9Very high0 Ų026 Ų260%013%0.125CC..Hα-helixtrans-65-39.7-179.5-62.20000111.6V204 Y205 A211 K212 F219 A237 A241V204-C208 PolarHBondContact O-N 3.01Å; V204-C208 VanDerWaalsContact O-N 3.12Å; V204-C208 PolarHBondContact O-SG 3.05Å; Y205-C208 PolarHBondContact O-N 3.38Å; Y205-C208 VanDerWaalsContact O-N 3.16Å; C208-A211 PolarHBondContact O-N 2.87Å; C208-K212 WeakPolarHBondContact O-CB 3.38Å; C208-K212 PolarHBondContact O-N 3.24Å; C208-F219 HydrophobicContact CB-CE1 4.28Å; C208-A237 HydrophobicContact CB-CB 4.35Å; C208-A241 HydrophobicContact CB-CB 4.03Å
209E98.6Very high97.7Very high76 Ų7625.2 Ų25.236%0.35512%0.12SC..Hα-helixtrans-56.5-57.1173.6-174.1-168.3153.500111Y205 K206 F207 A211 K212 E213Y205-E209 PolarHBondContact O-N 2.88Å; K206-E209 WeakPolarHBondContact CD-OE2 3.49Å; K206-E209 IonicContact NZ-OE1 2.93Å; K206-E209 PolarHBondContact NZ-OE1 3.4Å; K206-E209 IonicContact NZ-OE2 3.57Å; K206-E209 PolarHBondContact NZ-OE2 3.21Å; F207-E209 VanDerWaalsContact C-N 3.34Å; E209-A211 VanDerWaalsContact C-N 3.3Å; E209-A211 PolarHBondContact O-N 3.45Å; E209-K212 PolarHBondContact O-N 3.16Å; E209-K212 VanDerWaalsContact O-N 3.12Å; E209-E213 WeakPolarHBondContact O-CG 2.87Å; E209-E213 PolarHBondContact O-N 3.38Å
210V98.4Very high98Very high0 Ų024.5 Ų24.50%012%0.118CC..Hα-helixtrans-64-35.7-178.9179.20000111.3W169 K206 F207 N214 E550 M553W169-V210 HydrophobicContact CE3-CG1 4.22Å; W169-V210 HydrophobicContact CH2-CB 4.14Å; W169-V210 HydrophobicContact CH2-CG1 3.74Å; W169-V210 HydrophobicContact CZ2-CG1 4.39Å; W169-V210 HydrophobicContact CZ3-CB 4.28Å; W169-V210 HydrophobicContact CZ3-CG1 3.63Å; K206-V210 HydrophobicContact CD-CG2 4.23Å; K206-V210 HydrophobicContact CG-CG2 4.39Å; K206-V210 VanDerWaalsContact O-CG2 3.3Å; K206-V210 WeakPolarHBondContact O-CG2 3.47Å; K206-V210 PolarHBondContact O-N 3.41Å; F207-V210 PolarHBondContact O-N 3.39Å; V210-N214 WeakPolarHBondContact O-CB 3.22Å; V210-N214 PolarHBondContact O-N 3.04Å; V210-N214 VanDerWaalsContact O-N 3.11Å; V210-N214 PolarHBondContact O-ND2 3.42Å; V210-E550 HydrophobicContact CG1-CG 4.12Å; V210-M553 HydrophobicContact CB-CG 4.34Å; V210-M553 HydrophobicContact CG2-CG 3.99Å
211A98.5Very high98.2Very high0 Ų023.9 Ų23.90%011%0.114CC..Hα-helixtrans-62.3-43.9173.600000112.4W152 W169 M186 F207 C208 E209 N214 G215 M216 F219W152-A211 HydrophobicContact CZ3-CB 4.4Å; W169-A211 HydrophobicContact CZ3-CB 4.32Å; M186-A211 HydrophobicContact SD-CB 4.5Å; F207-A211 HydrophobicContact CE1-CB 4.33Å; F207-A211 VanDerWaalsContact O-CB 3.26Å; F207-A211 WeakPolarHBondContact O-CB 3.4Å; F207-A211 PolarHBondContact O-N 3.04Å; C208-A211 PolarHBondContact O-N 2.87Å; E209-A211 VanDerWaalsContact C-N 3.3Å; E209-A211 PolarHBondContact O-N 3.45Å; A211-N214 PolarHBondContact O-N 3.33Å; A211-G215 PolarHBondContact O-N 3.44Å; A211-M216 HydrophobicContact CB-CB 4.22Å; A211-M216 WeakPolarHBondContact O-CB 3.2Å; A211-M216 PolarHBondContact O-N 2.92Å; A211-F219 HydrophobicContact CB-CE1 3.93Å; A211-F219 HydrophobicContact CB-CZ 4.01Å
212K98.4Very high98.3Very high46 Ų4621.5 Ų21.520%0.210%0.101CC..Hα-helixtrans-66.6-44.3178.2-177.552.5174.6179.60111.7C208 E209 N214 G215 M216 D217 F219 A241 G242C208-K212 WeakPolarHBondContact O-CB 3.38Å; C208-K212 PolarHBondContact O-N 3.24Å; E209-K212 PolarHBondContact O-N 3.16Å; E209-K212 VanDerWaalsContact O-N 3.12Å; K212-N214 PolarHBondContact O-N 3.1Å; K212-G215 PolarHBondContact O-N 3Å; K212-M216 WeakPolarHBondContact CD-O 3.43Å; K212-M216 PolarHBondContact NZ-O 3.3Å; K212-D217 IonicContact NZ-OD1 3.26Å; K212-D217 PolarHBondContact NZ-OD1 3.02Å; K212-F219 HydrophobicContact CB-CZ 4.39Å; K212-A241 HydrophobicContact CB-CB 4.12Å; K212-A241 VanDerWaalsContact CG-O 3.3Å; K212-A241 WeakPolarHBondContact CG-O 3.32Å; K212-G242 WeakPolarHBondContact CE-O 3.42Å
213E98.2Very high98.2Very high131 Ų13119.3 Ų19.361%0.6129%0.089SC*.Hα-helixtrans-57.4-33.9175.4-71.3176.515900112.3E209 G215E209-E213 WeakPolarHBondContact O-CG 2.87Å; E209-E213 PolarHBondContact O-N 3.38Å; E213-G215 VanDerWaalsContact C-N 3.31Å; E213-G215 PolarHBondContact O-N 3.12Å
214N98.3Very high98Very high16 Ų1619.3 Ų19.39%0.0869%0.089CC..THydrogen-bonded Turntrans-84.93178.8-80.7-81.4000114.6W169 L172 Q173 V210 A211 K212 E550W169-N214 HydrophobicContact CE3-CB 4.27Å; L172-N214 HydrophobicContact CD2-CB 3.82Å; L172-N214 HydrophobicContact CG-CB 4.48Å; Q173-N214 WeakPolarHBondContact CG-OD1 3.43Å; Q173-N214 PolarHBondContact NE2-OD1 2.89Å; V210-N214 WeakPolarHBondContact O-CB 3.22Å; V210-N214 PolarHBondContact O-N 3.04Å; V210-N214 VanDerWaalsContact O-N 3.11Å; V210-N214 PolarHBondContact O-ND2 3.42Å; A211-N214 PolarHBondContact O-N 3.33Å; K212-N214 PolarHBondContact O-N 3.1Å; N214-E550 PolarHBondContact ND2-OE1 3.27Å; N214-E550 PolarHBondContact OD1-OE1 3.49Å
215G97.6Very high97.9Very high9 Ų919.5 Ų19.59%0.0939%0.09CC..THydrogen-bonded Turntrans101.315.6171.300000115.8R176 A211 K212 E213R176-G215 WeakPolarHBondContact CD-O 3.32Å; A211-G215 PolarHBondContact O-N 3.44Å; K212-G215 PolarHBondContact O-N 3Å; E213-G215 VanDerWaalsContact C-N 3.31Å; E213-G215 PolarHBondContact O-N 3.12Å
216M98.7Very high97.9Very high0 Ų016.9 Ų16.90%08%0.081CC..  trans-71.6135.9166.5-171.951.555.400110.6W152 L172 F184 Q185 M186 A211 K212 F219W152-M216 HydrophobicContact CB-CE 3.46Å; W152-M216 VanDerWaalsContact CB-CE 3.46Å; W152-M216 HydrophobicContact CD2-CE 4.36Å; W152-M216 HydrophobicContact CE3-CE 4.22Å; W152-M216 HydrophobicContact CG-CE 4.11Å; L172-M216 HydrophobicContact CD1-CE 3.76Å; L172-M216 HydrophobicContact CD2-CE 4.36Å; F184-M216 HydrophobicContact CB-CE 4.33Å; F184-M216 HydrophobicContact CB-SD 4.13Å; Q185-M216 VanDerWaalsContact C-SD 3.52Å; M186-M216 HydrophobicContact CB-CE 3.78Å; M186-M216 HydrophobicContact CB-CG 4.32Å; M186-M216 HydrophobicContact CB-SD 3.65Å; M186-M216 HydrophobicContact CG-CE 4.24Å; M186-M216 HydrophobicContact CG-CG 3.74Å; M186-M216 HydrophobicContact CG-SD 3.7Å; M186-M216 PolarHBondContact N-SD 2.97Å; M186-M216 VanDerWaalsContact N-SD 3.43Å; M186-M216 HydrophobicContact SD-CG 3.89Å; M186-M216 HydrophobicContact SD-SD 4.45Å; A211-M216 HydrophobicContact CB-CB 4.22Å; A211-M216 WeakPolarHBondContact O-CB 3.2Å; A211-M216 PolarHBondContact O-N 2.92Å; K212-M216 WeakPolarHBondContact CD-O 3.43Å; K212-M216 PolarHBondContact NZ-O 3.3Å; M216-F219 HydrophobicContact CB-CZ 4.07Å; M216-F219 HydrophobicContact CG-CE1 4.01Å; M216-F219 HydrophobicContact CG-CE2 4.05Å; M216-F219 HydrophobicContact CG-CZ 3.76Å
217D98.9Very high97.8Very high1 Ų115.8 Ų15.81%0.0058%0.075CC..  trans-111.2-45.5-173.9-66.9-50.9000112.7R87 L90 R176 P183 F184 K212 V244R87-D217 VanDerWaalsContact CD-OD2 3.3Å; R87-D217 WeakPolarHBondContact CD-OD2 3.38Å; R87-D217 IonicContact NE-OD1 3.21Å; R87-D217 IonicContact NE-OD2 3.37Å; R87-D217 PolarHBondContact NE-OD2 3.02Å; L90-D217 HydrophobicContact CD2-CB 3.59Å; R176-D217 IonicContact NH1-OD2 2.6Å; R176-D217 PolarHBondContact NH1-OD2 2.97Å; P183-D217 HydrophobicContact CB-CB 4.18Å; F184-D217 PolarHBondContact N-OD2 2.86Å; F184-D217 CarbonylContact O-C 3.25Å; F184-D217 WeakPolarHBondContact O-CA 3.38Å; F184-D217 WeakPolarHBondContact O-CB 3.18Å; F184-D217 PolarHBondContact O-N 3.36Å; K212-D217 IonicContact NZ-OD1 3.26Å; K212-D217 PolarHBondContact NZ-OD1 3.02Å; D217-V244 PolarHBondContact O-N 3.17Å
218I98.9Very high97.7Very high0 Ų017.6 Ų17.60%09%0.085CC..EExtended strand (participates in β ladder)trans-119.9128.3-173.9-48.9-177.9000110.1F98 F147 P183 F184 Q185 M186 V244 E246F98-I218 HydrophobicContact CE1-CD1 3.78Å; F98-I218 HydrophobicContact CE1-CG1 4.49Å; F98-I218 HydrophobicContact CZ-CD1 3.73Å; F147-I218 HydrophobicContact CE1-CD1 3.96Å; F147-I218 HydrophobicContact CE2-CD1 4.31Å; F147-I218 HydrophobicContact CZ-CD1 3.73Å; P183-I218 HydrophobicContact CB-CD1 3.92Å; P183-I218 HydrophobicContact CB-CG1 4.24Å; F184-I218 PolarHBondContact O-N 2.88Å; Q185-I218 WeakPolarHBondContact CA-O 3.46Å; Q185-I218 HydrophobicContact CB-CB 4.06Å; Q185-I218 HydrophobicContact CG-CB 4.06Å; Q185-I218 HydrophobicContact CG-CG2 4.14Å; M186-I218 PolarHBondContact N-O 2.84Å; I218-V244 HydrophobicContact CB-CB 4.29Å; I218-V244 HydrophobicContact CG1-CB 4.01Å; I218-V244 HydrophobicContact CG1-CG2 4.21Å; I218-V244 HydrophobicContact CG2-CB 4.17Å; I218-V244 HydrophobicContact CG2-CG1 4.3Å; I218-E246 HydrophobicContact CG2-CB 4.18Å
219F98.9Very high97.6Very high0 Ų020 Ų200%010%0.1CC..EExtended strand (participates in β ladder)trans-109.6104.3176.8-63.7-99.5000108.9M186 L188 C208 A211 K212 M216 V221 A238 V244 E246M186-F219 HydrophobicContact CG-CD1 3.84Å; M186-F219 HydrophobicContact CG-CE1 4.25Å; M186-F219 HydrophobicContact CG-CG 4.43Å; M186-F219 HydrophobicContact SD-CD1 3.54Å; M186-F219 VanDerWaalsContact SD-CD1 3.54Å; M186-F219 HydrophobicContact SD-CE1 3.5Å; M186-F219 WeakPolarHBondContact SD-CE1 3.38Å; L188-F219 HydrophobicContact CD2-CD1 4.23Å; C208-F219 HydrophobicContact CB-CE1 4.28Å; A211-F219 HydrophobicContact CB-CE1 3.93Å; A211-F219 HydrophobicContact CB-CZ 4.01Å; K212-F219 HydrophobicContact CB-CZ 4.39Å; M216-F219 HydrophobicContact CB-CZ 4.07Å; M216-F219 HydrophobicContact CG-CE1 4.01Å; M216-F219 HydrophobicContact CG-CE2 4.05Å; M216-F219 HydrophobicContact CG-CZ 3.76Å; F219-V221 HydrophobicContact CB-CG2 4.3Å; F219-V221 PolarHBondContact O-N 3.18Å; F219-A238 HydrophobicContact CB-CB 3.61Å; F219-A238 HydrophobicContact CD1-CB 4.2Å; F219-A238 HydrophobicContact CD2-CB 3.97Å; F219-A238 HydrophobicContact CG-CB 3.67Å; F219-V244 PolarHBondContact N-O 3.07Å; F219-E246 PolarHBondContact O-N 3.45Å
220R98.8Very high97.4Very high0 Ų016.4 Ų16.40%08%0.083CC..EExtended strand (participates in β ladder)trans-78.696.9170.6-177-178-77.1176.6-16.3108.8E150 Q185 M186 L187 L188 E246 A248 H314 D340E150-R220 IonicContact OE1-NH1 3.06Å; Q185-R220 VanDerWaalsContact NE2-CZ 3.26Å; M186-R220 WeakPolarHBondContact O-CB 3.47Å; M186-R220 PolarHBondContact O-N 2.7Å; L187-R220 HydrophobicContact CD1-CB 4.3Å; L187-R220 HydrophobicContact CD1-CG 3.96Å; L188-R220 PolarHBondContact N-O 2.9Å; R220-E246 CarbonylContact C-O 2.86Å; R220-E246 VanDerWaalsContact CA-O 3.31Å; R220-E246 WeakPolarHBondContact CA-O 3.3Å; R220-E246 HydrophobicContact CG-CG 4.32Å; R220-E246 IonicContact CZ-OE1 2.75Å; R220-E246 IonicContact NE-OE1 3.32Å; R220-E246 PolarHBondContact NE-OE1 3.06Å; R220-E246 IonicContact NE-OE2 3.44Å; R220-E246 IonicContact NH2-OE1 2.65Å; R220-E246 PolarHBondContact NH2-OE1 2.76Å; R220-A248 HydrophobicContact CG-CB 3.74Å; R220-H314 PolarHBondContact NH2-CE1 3.32Å; R220-H314 PolarHBondContact NH2-ND1 3.03Å; R220-H314 PolarHBondContact NH2-NE2 3.25Å; R220-H314 VanDerWaalsContact NH2-NE2 3.12Å; R220-D340 IonicContact CZ-OD1 2.9Å; R220-D340 IonicContact CZ-OD2 3.86Å; R220-D340 IonicContact NH1-OD1 2.7Å; R220-D340 IonicContact NH1-OD2 3.21Å; R220-D340 PolarHBondContact NH1-OD2 2.82Å; R220-D340 IonicContact NH2-OD1 3.02Å; R220-D340 PolarHBondContact NH2-OD1 3.26Å; R220-D340 VanDerWaalsContact NH2-OD1 3.09Å; R220-D340 IonicContact NH2-OD2 3.2Å; R220-D340 PolarHBondContact NH2-OD2 2.85Å
221V98.6Very high97.3Very high0 Ų016.4 Ų16.40%08%0.083CC..EExtended strand (participates in β ladder)trans-88.8117.1-175.9-171.50000110.3L188 F219 M235 A238 E246 A248L188-V221 HydrophobicContact CD2-CG2 4.06Å; L188-V221 WeakPolarHBondContact O-CA 3.41Å; F219-V221 HydrophobicContact CB-CG2 4.3Å; F219-V221 PolarHBondContact O-N 3.18Å; V221-M235 HydrophobicContact CB-CG 4.15Å; V221-M235 HydrophobicContact CG1-CG 4.15Å; V221-M235 HydrophobicContact CG2-CG 4.35Å; V221-A238 HydrophobicContact CG2-CB 4.47Å; V221-E246 PolarHBondContact N-O 3.34Å; V221-A248 PolarHBondContact O-N 2.9Å
222F97.7Very high97.3Very high1 Ų119.7 Ų19.70%0.00410%0.1CC..EExtended strand (participates in β ladder)trans-129162.2175.782.9-70.3000111.4L187 L188 R189 G190 A248 V452L187-F222 HydrophobicContact CD1-CD1 3.42Å; L187-F222 VanDerWaalsContact CD1-CD1 3.42Å; L187-F222 HydrophobicContact CD1-CE1 3.76Å; L187-F222 HydrophobicContact CD1-CG 4.19Å; L187-F222 HydrophobicContact CD2-CD1 4.34Å; L187-F222 HydrophobicContact CD2-CE1 3.85Å; L187-F222 HydrophobicContact CD2-CZ 4.28Å; L187-F222 HydrophobicContact CG-CD1 3.77Å; L187-F222 HydrophobicContact CG-CE1 3.54Å; L187-F222 HydrophobicContact CG-CZ 4.44Å; L188-F222 VanDerWaalsContact O-CD1 3.3Å; L188-F222 WeakPolarHBondContact O-CD1 3.23Å; L188-F222 PolarHBondContact O-N 2.66Å; R189-F222 CarbonylContact C-O 3.3Å; R189-F222 WeakPolarHBondContact CA-O 3.13Å; R189-F222 HydrophobicContact CB-CD1 4.45Å; R189-F222 HydrophobicContact CB-CE1 3.71Å; R189-F222 HydrophobicContact CB-CZ 3.97Å; R189-F222 HydrophobicContact CG-CE1 4.04Å; R189-F222 HydrophobicContact CG-CE2 4.36Å; R189-F222 HydrophobicContact CG-CZ 3.86Å; G190-F222 PolarHBondContact N-O 3.27Å; F222-A248 HydrophobicContact CB-CB 4.05Å; F222-V452 HydrophobicContact CD2-CG1 4.04Å; F222-V452 HydrophobicContact CD2-CG2 4.32Å; F222-V452 HydrophobicContact CE2-CB 4.36Å; F222-V452 HydrophobicContact CE2-CG1 3.71Å; F222-V452 HydrophobicContact CE2-CG2 3.68Å; F222-V452 HydrophobicContact CZ-CG2 4.4Å
223D96Very high97.2Very high0 Ų017.9 Ų17.90%09%0.093CC..  trans-123.1144165.4177.4-91.7000110.3L225 N226 Y227 N230 M231D223-L225 PolarHBondContact O-N 2.59Å; D223-L225 VanDerWaalsContact O-N 3.13Å; D223-L225 WeakPolarHBondContact OD1-CA 3.38Å; D223-L225 PolarHBondContact OD1-N 3.41Å; D223-N226 PolarHBondContact O-N 3.12Å; D223-N226 VanDerWaalsContact O-N 3.11Å; D223-N226 PolarHBondContact OD1-N 2.71Å; D223-Y227 VanDerWaalsContact OD1-CB 3.28Å; D223-Y227 WeakPolarHBondContact OD1-CB 3.2Å; D223-Y227 PolarHBondContact OD1-N 3.04Å; D223-N230 HydrophobicContact CB-CB 4.26Å; D223-N230 VanDerWaalsContact OD2-CB 3.26Å; D223-N230 WeakPolarHBondContact OD2-CB 3.14Å; D223-N230 PolarHBondContact OD2-ND2 3.44Å; D223-M231 HydrophobicContact CB-CG 3.5Å; D223-M231 VanDerWaalsContact CB-CG 3.5Å; D223-M231 HydrophobicContact CB-SD 4.23Å
224S93.3Very high97.2Very high0 Ų011.7 Ų11.70%06%0.064CC..THydrogen-bonded Turntrans-67.5-14-174.366.40000115.7I450 V452 S455 V497S224-I450 WeakPolarHBondContact O-CG2 3.33Å; S224-V452 VanDerWaalsContact CA-CG1 3.41Å; S224-S455 PolarHBondContact O-OG 3.41Å; S224-V497 VanDerWaalsContact OG-CG1 3.26Å; S224-V497 WeakPolarHBondContact OG-CG1 3.36Å
225L95.7Very high97.2Very high4 Ų411.4 Ų11.42%0.0216%0.062CC..THydrogen-bonded Turntrans-122.19.6178.2-58.1176.2000111.4D223 Y227 L449 I450 F492 V497 P500D223-L225 PolarHBondContact O-N 2.59Å; D223-L225 VanDerWaalsContact O-N 3.13Å; D223-L225 WeakPolarHBondContact OD1-CA 3.38Å; D223-L225 PolarHBondContact OD1-N 3.41Å; L225-Y227 PolarHBondContact O-N 3.14Å; L225-L449 HydrophobicContact CD2-CD2 4.41Å; L225-I450 WeakPolarHBondContact O-CD1 3.5Å; L225-F492 HydrophobicContact CD1-CE2 4.13Å; L225-F492 HydrophobicContact CD2-CE2 4.38Å; L225-V497 HydrophobicContact CD1-CG1 4.22Å; L225-V497 HydrophobicContact CG-CG1 4.48Å; L225-P500 HydrophobicContact CD1-CB 4.43Å; L225-P500 HydrophobicContact CD2-CB 4.47Å
226N97.5Very high97.3Very high10 Ų1016.5 Ų16.55%0.0538%0.084CC..  trans49.434.9-164.9-69.4-18.6000112.4D223 L228 S250 Y267 L271 I450D223-N226 PolarHBondContact O-N 3.12Å; D223-N226 VanDerWaalsContact O-N 3.11Å; D223-N226 PolarHBondContact OD1-N 2.71Å; N226-L228 PolarHBondContact O-N 3.24Å; N226-L228 VanDerWaalsContact O-N 3.13Å; N226-S250 PolarHBondContact ND2-O 3.4Å; N226-S250 VanDerWaalsContact OD1-CB 3.31Å; N226-S250 WeakPolarHBondContact OD1-CB 3.37Å; N226-S250 PolarHBondContact OD1-N 3.21Å; N226-S250 PolarHBondContact OD1-OG 3.22Å; N226-Y267 VanDerWaalsContact CB-OH 3.25Å; N226-Y267 WeakPolarHBondContact CB-OH 3.47Å; N226-Y267 PolarHBondContact ND2-OH 2.9Å; N226-Y267 VanDerWaalsContact ND2-OH 3.08Å; N226-L271 HydrophobicContact CB-CD2 3.73Å; N226-I450 HydrophobicContact CB-CD1 3.68Å; N226-I450 VanDerWaalsContact ND2-CD1 3.27Å; N226-I450 WeakPolarHBondContact ND2-CD1 3.36Å
227Y96Very high97.3Very high38 Ų3816.5 Ų16.515%0.1498%0.084CC..  trans-76.1100.9179.4-175.3-126.2000110.2D223 L225 P229 N230 M231 I499D223-Y227 VanDerWaalsContact OD1-CB 3.28Å; D223-Y227 WeakPolarHBondContact OD1-CB 3.2Å; D223-Y227 PolarHBondContact OD1-N 3.04Å; L225-Y227 PolarHBondContact O-N 3.14Å; Y227-P229 VanDerWaalsContact C-CD 3.47Å; Y227-P229 HydrophobicContact CD1-CB 4.45Å; Y227-P229 HydrophobicContact CD1-CG 4.49Å; Y227-P229 HydrophobicContact CD2-CG 4.4Å; Y227-P229 HydrophobicContact CE1-CB 3.91Å; Y227-P229 HydrophobicContact CE1-CG 3.94Å; Y227-P229 HydrophobicContact CE2-CG 3.82Å; Y227-N230 HydrophobicContact CD1-CB 4.34Å; Y227-N230 WeakPolarHBondContact O-CB 3.43Å; Y227-N230 PolarHBondContact O-N 3.06Å; Y227-M231 PolarHBondContact O-N 3.46Å; Y227-I499 HydrophobicContact CD2-CB 4.06Å; Y227-I499 WeakPolarHBondContact CD2-O 3.39Å; Y227-I499 HydrophobicContact CE2-CB 3.8Å; Y227-I499 HydrophobicContact CE2-CD1 4.21Å; Y227-I499 HydrophobicContact CE2-CG1 4.12Å
228L96.1Very high97.2Very high38 Ų3816.5 Ų16.520%0.1998%0.084CC..Hα-helixtrans-49.2-44.1-171.6-175.565.1000114.5N226 N230 M231 L232 L271 E274 L275N226-L228 PolarHBondContact O-N 3.24Å; N226-L228 VanDerWaalsContact O-N 3.13Å; L228-N230 PolarHBondContact O-N 3.01Å; L228-M231 WeakPolarHBondContact O-CB 3.24Å; L228-M231 PolarHBondContact O-N 2.73Å; L228-L232 HydrophobicContact CD1-CD2 4.09Å; L228-L232 HydrophobicContact CD1-CG 4.06Å; L228-L232 HydrophobicContact CG-CD1 4.07Å; L228-L232 HydrophobicContact CG-CG 4.06Å; L228-L232 WeakPolarHBondContact O-CG 3.43Å; L228-L232 PolarHBondContact O-N 3.31Å; L228-L271 HydrophobicContact CD1-CD1 4.28Å; L228-E274 HydrophobicContact CD1-CB 4.31Å; L228-E274 HydrophobicContact CD2-CB 3.79Å; L228-E274 HydrophobicContact CD2-CG 4.13Å; L228-L275 HydrophobicContact CD1-CD2 3.63Å; L228-L275 HydrophobicContact CD1-CG 4.42Å
229P95.9Very high97.2Very high50 Ų5018 Ų1833%0.32510%0.099SC..Hα-helixtrans-58.6-31.4178.9-27.938.6000114.7Y227Y227-P229 VanDerWaalsContact C-CD 3.47Å; Y227-P229 HydrophobicContact CD1-CB 4.45Å; Y227-P229 HydrophobicContact CD1-CG 4.49Å; Y227-P229 HydrophobicContact CD2-CG 4.4Å; Y227-P229 HydrophobicContact CE1-CB 3.91Å; Y227-P229 HydrophobicContact CE1-CG 3.94Å; Y227-P229 HydrophobicContact CE2-CG 3.82Å
230N95Very high97.2Very high0 Ų022 Ų220%013%0.128CC..Hα-helixtrans-73-39.9174.3-74.8-7000111.4G190 A191 D223 Y227 L228 G234 V497 R522G190-N230 CarbonylContact C-O 3.33Å; G190-N230 VanDerWaalsContact CA-O 3.25Å; G190-N230 WeakPolarHBondContact CA-O 3.21Å; A191-N230 HydrophobicContact CB-CB 3.96Å; A191-N230 PolarHBondContact N-O 2.76Å; D223-N230 HydrophobicContact CB-CB 4.26Å; D223-N230 VanDerWaalsContact OD2-CB 3.26Å; D223-N230 WeakPolarHBondContact OD2-CB 3.14Å; D223-N230 PolarHBondContact OD2-ND2 3.44Å; Y227-N230 HydrophobicContact CD1-CB 4.34Å; Y227-N230 WeakPolarHBondContact O-CB 3.43Å; Y227-N230 PolarHBondContact O-N 3.06Å; L228-N230 PolarHBondContact O-N 3.01Å; N230-G234 PolarHBondContact O-N 2.75Å; N230-V497 PolarHBondContact ND2-O 3.09Å; N230-R522 WeakPolarHBondContact OD1-CD 3.49Å; N230-R522 VanDerWaalsContact OD1-CG 3.26Å; N230-R522 WeakPolarHBondContact OD1-CG 3.34Å
231M96.8Very high97.2Very high0 Ų023.3 Ų23.30%014%0.138CC..Hα-helixtrans-64.6-45.2179.1-63.6-175.866.800111.1D223 Y227 L228 L233 G234 M235 A248 L275D223-M231 HydrophobicContact CB-CG 3.5Å; D223-M231 VanDerWaalsContact CB-CG 3.5Å; D223-M231 HydrophobicContact CB-SD 4.23Å; Y227-M231 PolarHBondContact O-N 3.46Å; L228-M231 WeakPolarHBondContact O-CB 3.24Å; L228-M231 PolarHBondContact O-N 2.73Å; M231-L233 VanDerWaalsContact C-N 3.33Å; M231-L233 PolarHBondContact O-N 3.02Å; M231-G234 PolarHBondContact O-N 3.42Å; M231-G234 VanDerWaalsContact O-N 3.09Å; M231-M235 VanDerWaalsContact O-CG 3.3Å; M231-M235 WeakPolarHBondContact O-CG 3.47Å; M231-M235 PolarHBondContact O-N 3.45Å; M231-A248 WeakPolarHBondContact CE-O 3.4Å; M231-L275 HydrophobicContact CB-CD2 4.39Å; M231-L275 HydrophobicContact CE-CD1 3.76Å; M231-L275 HydrophobicContact CE-CD2 3.67Å; M231-L275 HydrophobicContact CE-CG 4.38Å; M231-L275 HydrophobicContact SD-CD2 4.2Å
232L97.7Very high97.2Very high69 Ų6925 Ų2536%0.36116%0.156SC..Hα-helixtrans-57.6-43.6-179.4-66.8178.9000112.3L228 G234 M235 E236 A278L228-L232 HydrophobicContact CD1-CD2 4.09Å; L228-L232 HydrophobicContact CD1-CG 4.06Å; L228-L232 HydrophobicContact CG-CD1 4.07Å; L228-L232 HydrophobicContact CG-CG 4.06Å; L228-L232 WeakPolarHBondContact O-CG 3.43Å; L228-L232 PolarHBondContact O-N 3.31Å; L232-G234 PolarHBondContact O-N 3.44Å; L232-M235 HydrophobicContact CD2-SD 4.44Å; L232-M235 PolarHBondContact O-N 2.9Å; L232-E236 WeakPolarHBondContact O-CB 3.39Å; L232-E236 PolarHBondContact O-N 3.18Å; L232-A278 HydrophobicContact CD2-CB 3.36Å
233L97.4Very high97.2Very high9 Ų925 Ų255%0.04716%0.156CC..Hα-helixtrans-59.8-45.1175.3174.966000112A191 D201 V204 Y205 M231 E236 A237A191-L233 HydrophobicContact CB-CD2 3.94Å; D201-L233 HydrophobicContact CB-CD1 3.99Å; D201-L233 HydrophobicContact CB-CD2 4.43Å; V204-L233 HydrophobicContact CG2-CD2 4.33Å; Y205-L233 HydrophobicContact CD2-CD1 4.34Å; Y205-L233 HydrophobicContact CE2-CD1 3.57Å; M231-L233 VanDerWaalsContact C-N 3.33Å; M231-L233 PolarHBondContact O-N 3.02Å; L233-E236 PolarHBondContact O-N 3.07Å; L233-A237 VanDerWaalsContact O-CB 3.3Å; L233-A237 WeakPolarHBondContact O-CB 3.4Å; L233-A237 PolarHBondContact O-N 3.24Å
234G97.6Very high97.3Very high0 Ų025 Ų250%016%0.156CC..Hα-helixtrans-66.8-38.6179.300000112.6N230 M231 L232 A238N230-G234 PolarHBondContact O-N 2.75Å; M231-G234 PolarHBondContact O-N 3.42Å; M231-G234 VanDerWaalsContact O-N 3.09Å; L232-G234 PolarHBondContact O-N 3.44Å; G234-A238 WeakPolarHBondContact O-CB 3.36Å; G234-A238 PolarHBondContact O-N 2.89Å
235M98.6Very high97.6Very high10 Ų1025.3 Ų25.35%0.04916%0.158CC..Hα-helixtrans-63.2-46.7175-70.5173.163.200111V221 M231 L232 A238 G239 V245 A247 L275 A278V221-M235 HydrophobicContact CB-CG 4.15Å; V221-M235 HydrophobicContact CG1-CG 4.15Å; V221-M235 HydrophobicContact CG2-CG 4.35Å; M231-M235 VanDerWaalsContact O-CG 3.3Å; M231-M235 WeakPolarHBondContact O-CG 3.47Å; M231-M235 PolarHBondContact O-N 3.45Å; L232-M235 HydrophobicContact CD2-SD 4.44Å; L232-M235 PolarHBondContact O-N 2.9Å; M235-A238 PolarHBondContact O-N 2.84Å; M235-G239 PolarHBondContact O-N 3.49Å; M235-V245 HydrophobicContact CB-CG1 3.79Å; M235-V245 HydrophobicContact CE-CG1 4.12Å; M235-V245 HydrophobicContact CG-CG1 3.66Å; M235-V245 WeakPolarHBondContact O-CG2 3.33Å; M235-A247 HydrophobicContact CE-CB 4.04Å; M235-A247 HydrophobicContact SD-CB 3.85Å; M235-L275 HydrophobicContact SD-CD2 3.8Å; M235-A278 HydrophobicContact CE-CB 3.76Å
236E98.5Very high97.8Very high116 Ų11625.1 Ų25.154%0.54216%0.157SC..Hα-helixtrans-63.6-43.1178.2-165.8-178.3-176.200111.5Y205 L232 L233 S240Y205-E236 HydrophobicContact CE1-CG 4.39Å; Y205-E236 WeakPolarHBondContact OH-CG 3.33Å; Y205-E236 PolarHBondContact OH-OE1 2.91Å; Y205-E236 PolarHBondContact OH-OE2 3.34Å; L232-E236 WeakPolarHBondContact O-CB 3.39Å; L232-E236 PolarHBondContact O-N 3.18Å; L233-E236 PolarHBondContact O-N 3.07Å; E236-S240 WeakPolarHBondContact O-CB 3.13Å; E236-S240 PolarHBondContact O-N 3.02Å; E236-S240 PolarHBondContact O-OG 3.37Å
237A98.5Very high97.8Very high1 Ų124.6 Ų24.61%0.00815%0.154CC..Hα-helixtrans-63.1-45.9176.700000112.8V204 Y205 C208 L233 A241V204-A237 HydrophobicContact CG1-CB 3.96Å; Y205-A237 HydrophobicContact CD1-CB 3.97Å; Y205-A237 HydrophobicContact CD2-CB 4.41Å; Y205-A237 HydrophobicContact CE1-CB 4.16Å; Y205-A237 HydrophobicContact CG-CB 4.09Å; C208-A237 HydrophobicContact CB-CB 4.35Å; L233-A237 VanDerWaalsContact O-CB 3.3Å; L233-A237 WeakPolarHBondContact O-CB 3.4Å; L233-A237 PolarHBondContact O-N 3.24Å; A237-A241 PolarHBondContact O-N 2.86Å; A237-A241 VanDerWaalsContact O-N 3.13Å
238A98.5Very high97.9Very high0 Ų022.8 Ų22.80%015%0.147CC..Hα-helixtrans-66.7-42.9177.800000112.4F219 V221 G234 M235 A241 G242 G243 V245F219-A238 HydrophobicContact CB-CB 3.61Å; F219-A238 HydrophobicContact CD1-CB 4.2Å; F219-A238 HydrophobicContact CD2-CB 3.97Å; F219-A238 HydrophobicContact CG-CB 3.67Å; V221-A238 HydrophobicContact CG2-CB 4.47Å; G234-A238 WeakPolarHBondContact O-CB 3.36Å; G234-A238 PolarHBondContact O-N 2.89Å; M235-A238 PolarHBondContact O-N 2.84Å; A238-A241 PolarHBondContact O-N 2.88Å; A238-G242 PolarHBondContact O-N 2.61Å; A238-G243 PolarHBondContact O-N 3.19Å; A238-V245 HydrophobicContact CB-CG2 4.16Å
239G98.5Very high98.1Very high32 Ų3221 Ų2133%0.3314%0.138SC..Hα-helixtrans-65.1-42.9176.700000112.2M235 A241 G242M235-G239 PolarHBondContact O-N 3.49Å; G239-A241 VanDerWaalsContact C-N 3.25Å; G239-A241 PolarHBondContact O-N 3.47Å; G239-G242 WeakPolarHBondContact O-CA 3.49Å; G239-G242 PolarHBondContact O-N 3.25Å
240S98.5Very high98.2Very high85 Ų8518.6 Ų18.659%0.59412%0.122SC*.Hα-helixtrans-63.7-30.7176.9-61.20000112.8E236 G242E236-S240 WeakPolarHBondContact O-CB 3.13Å; E236-S240 PolarHBondContact O-N 3.02Å; E236-S240 PolarHBondContact O-OG 3.37Å; S240-G242 PolarHBondContact O-N 3.03Å
241A98.4Very high98.3Very high26 Ų2618.6 Ų18.622%0.21512%0.122CC..THydrogen-bonded Turntrans-72-13.7172.300000113.1C208 K212 A237 A238 G239C208-A241 HydrophobicContact CB-CB 4.03Å; K212-A241 HydrophobicContact CB-CB 4.12Å; K212-A241 VanDerWaalsContact CG-O 3.3Å; K212-A241 WeakPolarHBondContact CG-O 3.32Å; A237-A241 PolarHBondContact O-N 2.86Å; A237-A241 VanDerWaalsContact O-N 3.13Å; A238-A241 PolarHBondContact O-N 2.88Å; G239-A241 VanDerWaalsContact C-N 3.25Å; G239-A241 PolarHBondContact O-N 3.47Å
242G98.3Very high98.4Very high37 Ų3718.7 Ų18.738%0.38112%0.123SC..THydrogen-bonded Turntrans86.520.1-174.700000114K212 A238 G239 S240K212-G242 WeakPolarHBondContact CE-O 3.42Å; A238-G242 PolarHBondContact O-N 2.61Å; G239-G242 WeakPolarHBondContact O-CA 3.49Å; G239-G242 PolarHBondContact O-N 3.25Å; S240-G242 PolarHBondContact O-N 3.03Å
243G98.4Very high98.3Very high1 Ų115.6 Ų15.61%0.0111%0.107CC..  trans-83.6159.3174.600000113.2A238 V245A238-G243 PolarHBondContact O-N 3.19Å; G243-V245 PolarHBondContact O-N 3.33Å
244V98.9Very high98.2Very high0 Ų016.1 Ų16.10%011%0.11CC..EExtended strand (participates in β ladder)trans-72.4119166.5-175.60000108.4L90 P95 F98 D217 I218 F219 H281 I282L90-V244 HydrophobicContact CD1-CG2 3.41Å; L90-V244 VanDerWaalsContact CD1-CG2 3.41Å; L90-V244 HydrophobicContact CD2-CG2 3.9Å; L90-V244 HydrophobicContact CG-CG2 4.32Å; P95-V244 HydrophobicContact CB-CG2 4.08Å; P95-V244 HydrophobicContact CG-CG2 4.43Å; F98-V244 HydrophobicContact CD1-CG1 3.98Å; F98-V244 HydrophobicContact CD1-CG2 3.81Å; F98-V244 HydrophobicContact CE1-CG1 4.15Å; F98-V244 HydrophobicContact CE1-CG2 4.26Å; F98-V244 HydrophobicContact CG-CG2 4.45Å; D217-V244 PolarHBondContact O-N 3.17Å; I218-V244 HydrophobicContact CB-CB 4.29Å; I218-V244 HydrophobicContact CG1-CB 4.01Å; I218-V244 HydrophobicContact CG1-CG2 4.21Å; I218-V244 HydrophobicContact CG2-CB 4.17Å; I218-V244 HydrophobicContact CG2-CG1 4.3Å; F219-V244 PolarHBondContact N-O 3.07Å; V244-H281 HydrophobicContact CG1-CB 3.96Å; V244-I282 HydrophobicContact CG1-CD1 4.11Å; V244-I282 HydrophobicContact CG1-CG1 4.44Å
245V98.9Very high98.2Very high5 Ų517.1 Ų17.13%0.0312%0.116CC..EExtended strand (participates in β ladder)trans-85112.2175.2-176.70000109.8M235 A238 G243 T280 H281 I282M235-V245 HydrophobicContact CB-CG1 3.79Å; M235-V245 HydrophobicContact CE-CG1 4.12Å; M235-V245 HydrophobicContact CG-CG1 3.66Å; M235-V245 WeakPolarHBondContact O-CG2 3.33Å; A238-V245 HydrophobicContact CB-CG2 4.16Å; G243-V245 PolarHBondContact O-N 3.33Å; V245-T280 PolarHBondContact O-OG1 3.23Å; V245-H281 WeakPolarHBondContact CB-ND1 3.04Å; V245-H281 PolarHBondContact N-ND1 2.94Å; V245-H281 WeakPolarHBondContact O-CB 3.36Å; V245-H281 PolarHBondContact O-N 3.05Å; V245-I282 PolarHBondContact O-N 3.32Å
246E98.9Very high98Very high0 Ų018.6 Ų18.60%013%0.128CC..EExtended strand (participates in β ladder)trans-107.2104.2168.6177.3-171.9155.800108.9Q185 I218 F219 R220 V221 A248 I282 S284 H314Q185-E246 PolarHBondContact NE2-OE2 2.93Å; I218-E246 HydrophobicContact CG2-CB 4.18Å; F219-E246 PolarHBondContact O-N 3.45Å; R220-E246 CarbonylContact C-O 2.86Å; R220-E246 VanDerWaalsContact CA-O 3.31Å; R220-E246 WeakPolarHBondContact CA-O 3.3Å; R220-E246 HydrophobicContact CG-CG 4.32Å; R220-E246 IonicContact CZ-OE1 2.75Å; R220-E246 IonicContact NE-OE1 3.32Å; R220-E246 PolarHBondContact NE-OE1 3.06Å; R220-E246 IonicContact NE-OE2 3.44Å; R220-E246 IonicContact NH2-OE1 2.65Å; R220-E246 PolarHBondContact NH2-OE1 2.76Å; V221-E246 PolarHBondContact N-O 3.34Å; E246-A248 PolarHBondContact O-N 3.25Å; E246-I282 WeakPolarHBondContact CA-O 3.32Å; E246-I282 HydrophobicContact CB-CB 4.12Å; E246-I282 HydrophobicContact CB-CG2 4.48Å; E246-I282 HydrophobicContact CG-CB 4.04Å; E246-I282 HydrophobicContact CG-CG2 3.88Å; E246-S284 WeakPolarHBondContact OE1-CB 3.4Å; E246-S284 PolarHBondContact OE1-OG 3.13Å; E246-H314 IonicContact OE1-CG 2.84Å; E246-H314 IonicContact OE1-ND1 3.59Å; E246-H314 PolarHBondContact OE1-ND1 2.72Å; E246-H314 IonicContact OE2-ND1 3.89Å
247A98.8Very high97.9Very high0 Ų015.5 Ų15.50%012%0.115CC..EExtended strand (participates in β ladder)trans-81119.3176.800000110.5M235 L275 T280 I282 S284M235-A247 HydrophobicContact CE-CB 4.04Å; M235-A247 HydrophobicContact SD-CB 3.85Å; A247-L275 HydrophobicContact CB-CB 3.99Å; A247-L275 HydrophobicContact CB-CD1 3.99Å; A247-L275 HydrophobicContact CB-CD2 4.09Å; A247-L275 HydrophobicContact CB-CG 4.24Å; A247-T280 HydrophobicContact CB-CG2 4.32Å; A247-T280 WeakPolarHBondContact CB-OG1 3.45Å; A247-T280 PolarHBondContact N-OG1 3.18Å; A247-I282 PolarHBondContact N-O 2.84Å; A247-I282 VanDerWaalsContact N-O 3.09Å; A247-S284 PolarHBondContact O-N 2.86Å
248A98.6Very high97.5Very high0 Ų020.2 Ų20.20%015%0.145CC..EExtended strand (participates in β ladder)trans-108.3121.9-174.400000112.6R220 V221 F222 M231 E246 S284 K286R220-A248 HydrophobicContact CG-CB 3.74Å; V221-A248 PolarHBondContact O-N 2.9Å; F222-A248 HydrophobicContact CB-CB 4.05Å; M231-A248 WeakPolarHBondContact CE-O 3.4Å; E246-A248 PolarHBondContact O-N 3.25Å; A248-S284 CarbonylContact C-O 3.18Å; A248-S284 WeakPolarHBondContact CA-O 3.44Å; A248-K286 HydrophobicContact CB-CB 4.38Å
249I98.8Very high97.2Very high0 Ų028 Ų280%018%0.183CC..EExtended strand (participates in β ladder)trans-89.6117.1172.8-56.7173.2000108.7Y251 Y268 L271 A272 L275 L283 S284 I285 K286I249-Y251 PolarHBondContact O-N 2.85Å; I249-Y268 HydrophobicContact CG2-CD1 3.63Å; I249-Y268 HydrophobicContact CG2-CE1 3.91Å; I249-L271 HydrophobicContact CB-CD2 4.34Å; I249-L271 HydrophobicContact CD1-CB 4.31Å; I249-L271 HydrophobicContact CD1-CD2 4.31Å; I249-L271 HydrophobicContact CD1-CG 4.11Å; I249-L271 HydrophobicContact CG1-CD2 3.97Å; I249-L271 HydrophobicContact CG1-CG 4.1Å; I249-L271 HydrophobicContact CG2-CD2 3.62Å; I249-A272 HydrophobicContact CD1-CB 3.86Å; I249-L275 HydrophobicContact CD1-CD1 4.04Å; I249-L275 HydrophobicContact CG1-CD1 3.52Å; I249-L283 HydrophobicContact CD1-CD1 4.14Å; I249-S284 PolarHBondContact N-O 3.01Å; I249-I285 HydrophobicContact CB-CD1 4.01Å; I249-I285 HydrophobicContact CD1-CD1 4.19Å; I249-K286 PolarHBondContact O-N 3.45Å
250S98.4Very high96.8Very high0 Ų029.7 Ų29.70%018%0.18CC..EExtended strand (participates in β ladder)trans-71.7122.7175.4-57.40000110N226 K286 I450N226-S250 PolarHBondContact ND2-O 3.4Å; N226-S250 VanDerWaalsContact OD1-CB 3.31Å; N226-S250 WeakPolarHBondContact OD1-CB 3.37Å; N226-S250 PolarHBondContact OD1-N 3.21Å; N226-S250 PolarHBondContact OD1-OG 3.22Å; S250-K286 CarbonylContact C-O 3.35Å; S250-K286 WeakPolarHBondContact CA-O 3.49Å; S250-I450 VanDerWaalsContact CB-CG2 3.47Å
251Y98.4Very high96.5Very high0 Ų031.3 Ų31.30%018%0.178CC..PPolyproline II helixtrans-89.3132.9-178.3-178.4-92.3000111.4I249 G253 D254 V255 Y268 K286 D287 M288 L291 L292 L300I249-Y251 PolarHBondContact O-N 2.85Å; Y251-G253 WeakPolarHBondContact CE1-O 3.48Å; Y251-D254 WeakPolarHBondContact OH-CA 3.31Å; Y251-V255 HydrophobicContact CE2-CG1 3.78Å; Y251-V255 HydrophobicContact CE2-CG2 4.28Å; Y251-V255 PolarHBondContact OH-N 3.16Å; Y251-V255 VanDerWaalsContact OH-N 3.12Å; Y251-Y268 AromaticContact CD2-CE1 3.91Å; Y251-Y268 HydrophobicContact CD2-CE1 3.91Å; Y251-Y268 AromaticContact CD2-CE2 3.94Å; Y251-Y268 HydrophobicContact CD2-CE2 3.94Å; Y251-Y268 AromaticContact CD2-CZ 3.53Å; Y251-Y268 AromaticContact CE2-CE2 3.89Å; Y251-Y268 HydrophobicContact CE2-CE2 3.89Å; Y251-Y268 AromaticContact CE2-CZ 3.94Å; Y251-K286 PolarHBondContact N-O 3.41Å; Y251-D287 HydrophobicContact CD1-CB 4.3Å; Y251-M288 WeakPolarHBondContact O-CE 3.46Å; Y251-M288 VanDerWaalsContact O-SD 3.37Å; Y251-L291 HydrophobicContact CD1-CB 4.06Å; Y251-L291 HydrophobicContact CE1-CB 3.8Å; Y251-L292 HydrophobicContact CD1-CD2 4.07Å; Y251-L292 HydrophobicContact CD1-CG 3.79Å; Y251-L292 HydrophobicContact CD2-CD2 3.91Å; Y251-L292 HydrophobicContact CD2-CG 4.32Å; Y251-L292 HydrophobicContact CE1-CD2 3.74Å; Y251-L292 HydrophobicContact CE1-CG 3.81Å; Y251-L292 HydrophobicContact CE2-CD2 3.54Å; Y251-L292 HydrophobicContact CE2-CG 4.31Å; Y251-L292 HydrophobicContact CG-CD2 4.16Å; Y251-L292 HydrophobicContact CG-CG 4.06Å; Y251-L292 VanDerWaalsContact CZ-CD2 3.45Å; Y251-L300 HydrophobicContact CD2-CD2 3.84Å; Y251-L300 HydrophobicContact CE2-CD2 3.98Å
252T97.6Very high96.4Very high1 Ų132.9 Ų32.91%0.00618%0.18CC..  trans-145.7165.1171.6-160.90000110.2Y263 Y268 I450T252-Y263 HydrophobicContact CG2-CD1 3.96Å; T252-Y263 HydrophobicContact CG2-CD2 3.41Å; T252-Y263 VanDerWaalsContact CG2-CD2 3.41Å; T252-Y263 HydrophobicContact CG2-CE1 4.05Å; T252-Y263 HydrophobicContact CG2-CE2 3.51Å; T252-Y263 HydrophobicContact CG2-CG 3.63Å; T252-Y268 PolarHBondContact N-OH 3.35Å; T252-Y268 PolarHBondContact O-OH 3.27Å; T252-I450 HydrophobicContact CG2-CB 4.41Å; T252-I450 HydrophobicContact CG2-CG1 3.59Å
253G95.3Very high96.3Very high4 Ų431.4 Ų31.44%0.04116%0.163CC..SBendtrans74.7-153.1-176.100000113Y251 E410Y251-G253 WeakPolarHBondContact CE1-O 3.48Å; G253-E410 PolarHBondContact N-OE1 3.45Å
254D96.6Very high96.3Very high20 Ų2032.4 Ų32.411%0.10717%0.17CC..  trans-149.2103.7-176.6-173.97.4000110.3Y251 S256 D257 K293Y251-D254 WeakPolarHBondContact OH-CA 3.31Å; D254-S256 PolarHBondContact O-N 3.44Å; D254-S256 PolarHBondContact OD1-N 2.92Å; D254-S256 PolarHBondContact OD1-OG 3Å; D254-D257 HydrophobicContact CB-CB 3.84Å; D254-D257 PolarHBondContact O-N 2.8Å; D254-K293 WeakPolarHBondContact OD1-CE 3.32Å; D254-K293 IonicContact OD1-NZ 2.83Å; D254-K293 WeakPolarHBondContact OD2-CE 3.4Å; D254-K293 IonicContact OD2-NZ 2.89Å; D254-K293 PolarHBondContact OD2-NZ 3.42Å
255V96.8Very high96.2Very high21 Ų2135.1 Ų35.113%0.12718%0.184CC..THydrogen-bonded Turntrans-66.6-16.2-177.8-67.20000113.5Y251 Y268 L300Y251-V255 HydrophobicContact CE2-CG1 3.78Å; Y251-V255 HydrophobicContact CE2-CG2 4.28Å; Y251-V255 PolarHBondContact OH-N 3.16Å; Y251-V255 VanDerWaalsContact OH-N 3.12Å; V255-Y268 HydrophobicContact CG1-CD2 3.48Å; V255-Y268 VanDerWaalsContact CG1-CD2 3.48Å; V255-Y268 HydrophobicContact CG1-CE2 3.44Å; V255-Y268 VanDerWaalsContact CG1-CE2 3.44Å; V255-L300 HydrophobicContact CG2-CB 4.32Å
256S95.4Very high96.2Very high41 Ų4138.9 Ų38.929%0.28720%0.204SC..THydrogen-bonded Turntrans-91.4-5.1173.9710000113.4D254 P258D254-S256 PolarHBondContact O-N 3.44Å; D254-S256 PolarHBondContact OD1-N 2.92Å; D254-S256 PolarHBondContact OD1-OG 3Å; S256-P258 WeakPolarHBondContact O-CD 3.38Å
257D95.1Very high96.1Very high52 Ų5240.1 Ų40.128%0.27821%0.209SC..  trans-93.4110.3176.9-174.1-6.9000111.3D254 M259 R260D254-D257 HydrophobicContact CB-CB 3.84Å; D254-D257 PolarHBondContact O-N 2.8Å; D257-M259 PolarHBondContact O-N 3.44Å; D257-M259 VanDerWaalsContact O-N 3.1Å; D257-M259 VanDerWaalsContact OD1-CB 3.32Å; D257-M259 WeakPolarHBondContact OD1-CB 3.37Å; D257-M259 PolarHBondContact OD1-N 3.48Å; D257-R260 HydrophobicContact CB-CB 4.35Å; D257-R260 HydrophobicContact CB-CG 4.41Å; D257-R260 PolarHBondContact O-N 3.49Å; D257-R260 VanDerWaalsContact O-N 3.13Å
258P90.9Very high96.1Very high99 Ų9940.1 Ų40.164%0.64321%0.209SC*.THydrogen-bonded Turntrans-64.4-15.3178.228.8-35.5000113.3S256 Q261S256-P258 WeakPolarHBondContact O-CD 3.38Å; P258-Q261 VanDerWaalsContact C-NE2 3.26Å; P258-Q261 WeakPolarHBondContact O-CG 3.15Å; P258-Q261 PolarHBondContact O-NE2 3Å
259M92.7Very high96.1Very high163 Ų16341.6 Ų41.680%0.80322%0.218SC*.THydrogen-bonded Turntrans-85.5-15.3177.8-58.9-56.8-60.800113.4D257D257-M259 PolarHBondContact O-N 3.44Å; D257-M259 VanDerWaalsContact O-N 3.1Å; D257-M259 VanDerWaalsContact OD1-CB 3.32Å; D257-M259 WeakPolarHBondContact OD1-CB 3.37Å; D257-M259 PolarHBondContact OD1-N 3.48Å
260R89.4Confident96.1Very high69 Ų6947.4 Ų47.426%0.2624%0.244SC..  trans-104.772.1-179.9-66.5-164.577.3-176.2-1.1112.3D257 E410 D448D257-R260 HydrophobicContact CB-CB 4.35Å; D257-R260 HydrophobicContact CB-CG 4.41Å; D257-R260 PolarHBondContact O-N 3.49Å; D257-R260 VanDerWaalsContact O-N 3.13Å; R260-E410 IonicContact CZ-OE1 3.11Å; R260-E410 VanDerWaalsContact CZ-OE1 3.27Å; R260-E410 IonicContact NH1-OE1 3.2Å; R260-E410 PolarHBondContact NH1-OE1 2.73Å; R260-E410 IonicContact NH2-OE1 3.81Å; R260-E410 PolarHBondContact NH2-OE1 2.97Å; R260-E410 IonicContact NH2-OE2 3.32Å; R260-D448 IonicContact NH2-OD1 2.81Å; R260-D448 IonicContact NH2-OD2 3.58Å
261Q92.3Very high96.1Very high118 Ų11848.2 Ų48.255%0.55125%0.248SC*.  trans-85.2-9.1-172.2-65.2-55-54.400116.3P258 Y263P258-Q261 VanDerWaalsContact C-NE2 3.26Å; P258-Q261 WeakPolarHBondContact O-CG 3.15Å; P258-Q261 PolarHBondContact O-NE2 3Å; Q261-Y263 VanDerWaalsContact C-N 3.34Å; Q261-Y263 PolarHBondContact O-N 3.26Å
262K95.5Very high96.1Very high60 Ų6048.2 Ų48.226%0.26125%0.248SC..THydrogen-bonded Turntrans-62.6-41.6179-175.1179.4179.7-170.80112.1G447 D448 H501K262-G447 PolarHBondContact NZ-O 3.48Å; K262-D448 HydrophobicContact CD-CB 4.23Å; K262-D448 PolarHBondContact NZ-O 3.04Å; K262-H501 WeakPolarHBondContact CE-O 3.29Å; K262-H501 PolarHBondContact NZ-O 2.78Å
263Y97.3Very high96.2Very high5 Ų549.6 Ų49.62%0.0226%0.255CS..THydrogen-bonded Turntrans-116.162.9177.6-57.9-74.2000109.1T252 Q261 Y267 Y268 D448 I450 H501T252-Y263 HydrophobicContact CG2-CD1 3.96Å; T252-Y263 HydrophobicContact CG2-CD2 3.41Å; T252-Y263 VanDerWaalsContact CG2-CD2 3.41Å; T252-Y263 HydrophobicContact CG2-CE1 4.05Å; T252-Y263 HydrophobicContact CG2-CE2 3.51Å; T252-Y263 HydrophobicContact CG2-CG 3.63Å; Q261-Y263 VanDerWaalsContact C-N 3.34Å; Q261-Y263 PolarHBondContact O-N 3.26Å; Y263-Y267 HydrophobicContact CD1-CD1 4.04Å; Y263-Y267 AromaticContact CD1-CE1 3.72Å; Y263-Y267 HydrophobicContact CD1-CE1 3.72Å; Y263-Y267 HydrophobicContact CD1-CE2 4.39Å; Y263-Y267 AromaticContact CD1-CZ 3.92Å; Y263-Y267 HydrophobicContact CE1-CE1 4.45Å; Y263-Y268 WeakPolarHBondContact O-CE2 3.11Å; Y263-D448 WeakPolarHBondContact CE2-O 3.35Å; Y263-D448 PolarHBondContact OH-O 3.06Å; Y263-I450 HydrophobicContact CD1-CG1 4.48Å; Y263-I450 HydrophobicContact CE1-CD1 3.79Å; Y263-I450 HydrophobicContact CE1-CG1 3.77Å; Y263-I450 PolarHBondContact OH-N 3.43Å; Y263-H501 HydrophobicContact CE1-CB 4.17Å
264S97.3Very high96.3Very high22 Ų2253.3 Ų53.315%0.15427%0.271CS..  trans-75.3170.7-178.966.50000112.5D266 Y267 Y268S264-D266 PolarHBondContact O-N 3.05Å; S264-Y267 WeakPolarHBondContact O-CB 3.26Å; S264-Y267 PolarHBondContact O-N 2.93Å; S264-Y267 VanDerWaalsContact O-N 3.12Å; S264-Y267 PolarHBondContact OG-N 3.47Å; S264-Y268 WeakPolarHBondContact O-CD2 3.42Å; S264-Y268 PolarHBondContact O-N 3.43Å
265L97.8Very high96.4Very high58 Ų5852.4 Ų52.430%0.30427%0.266SS..Hα-helixtrans-54.6-41172.1-177.561.8000112.2Y267 Y268 V269 L300 A303L265-Y267 VanDerWaalsContact C-N 3.33Å; L265-Y267 PolarHBondContact O-N 3.41Å; L265-Y268 PolarHBondContact O-N 2.75Å; L265-V269 HydrophobicContact CD1-CG2 4.34Å; L265-V269 HydrophobicContact CG-CG2 4.42Å; L265-V269 WeakPolarHBondContact O-CG2 3.36Å; L265-V269 PolarHBondContact O-N 3.24Å; L265-L300 HydrophobicContact CD1-CB 4.36Å; L265-L300 HydrophobicContact CD1-CD1 3.84Å; L265-A303 HydrophobicContact CD1-CB 4.04Å; L265-A303 HydrophobicContact CD2-CB 4.24Å; L265-A303 HydrophobicContact CG-CB 4.46Å
266D97.6Very high96.5Very high84 Ų8453.2 Ų53.245%0.44927%0.271SS..Hα-helixtrans-63.1-36.8178175.972.6000112.4S264 Y268 K270S264-D266 PolarHBondContact O-N 3.05Å; D266-Y268 PolarHBondContact O-N 3.47Å; D266-K270 WeakPolarHBondContact O-CB 3.24Å; D266-K270 VanDerWaalsContact O-CG 3.3Å; D266-K270 WeakPolarHBondContact O-CG 3.2Å; D266-K270 PolarHBondContact O-N 2.77Å; D266-K270 WeakPolarHBondContact OD1-CE 3.46Å; D266-K270 IonicContact OD1-NZ 3.4Å; D266-K270 PolarHBondContact OD1-NZ 3.26Å; D266-K270 WeakPolarHBondContact OD2-CD 3.14Å; D266-K270 WeakPolarHBondContact OD2-CE 3.15Å; D266-K270 IonicContact OD2-NZ 3.89Å; D266-K270 PolarHBondContact OD2-NZ 2.92Å
267Y98.2Very high96.6Very high25 Ų2557.6 Ų57.610%0.09829%0.285CS..Hα-helixtrans-57.8-49172.8163.3-92.9000111.3N226 Y263 S264 L265 L271 H501N226-Y267 VanDerWaalsContact CB-OH 3.25Å; N226-Y267 WeakPolarHBondContact CB-OH 3.47Å; N226-Y267 PolarHBondContact ND2-OH 2.9Å; N226-Y267 VanDerWaalsContact ND2-OH 3.08Å; Y263-Y267 HydrophobicContact CD1-CD1 4.04Å; Y263-Y267 AromaticContact CD1-CE1 3.72Å; Y263-Y267 HydrophobicContact CD1-CE1 3.72Å; Y263-Y267 HydrophobicContact CD1-CE2 4.39Å; Y263-Y267 AromaticContact CD1-CZ 3.92Å; Y263-Y267 HydrophobicContact CE1-CE1 4.45Å; S264-Y267 WeakPolarHBondContact O-CB 3.26Å; S264-Y267 PolarHBondContact O-N 2.93Å; S264-Y267 VanDerWaalsContact O-N 3.12Å; S264-Y267 PolarHBondContact OG-N 3.47Å; L265-Y267 VanDerWaalsContact C-N 3.33Å; L265-Y267 PolarHBondContact O-N 3.41Å; Y267-L271 WeakPolarHBondContact O-CB 3.47Å; Y267-L271 PolarHBondContact O-N 3.13Å; Y267-L271 VanDerWaalsContact O-N 3.07Å; Y267-H501 AromaticContact CD2-CE1 3.72Å; Y267-H501 AromaticContact CD2-ND1 4Å; Y267-H501 AromaticContact CD2-NE2 3.75Å; Y267-H501 HydrophobicContact CE2-CB 4.29Å; Y267-H501 AromaticContact CE2-CD2 3.93Å; Y267-H501 AromaticContact CE2-CE1 3.87Å; Y267-H501 AromaticContact CE2-CG 3.69Å; Y267-H501 AromaticContact CE2-ND1 3.65Å
268Y98.6Very high96.8Very high0 Ų057.4 Ų57.40%029%0.291CS..Hα-helixtrans-66.5-44-178.9-70.1-70.6000112.5I249 Y251 T252 V255 Y263 S264 L265 D266 L271 A272 L300I249-Y268 HydrophobicContact CG2-CD1 3.63Å; I249-Y268 HydrophobicContact CG2-CE1 3.91Å; Y251-Y268 AromaticContact CD2-CE1 3.91Å; Y251-Y268 HydrophobicContact CD2-CE1 3.91Å; Y251-Y268 AromaticContact CD2-CE2 3.94Å; Y251-Y268 HydrophobicContact CD2-CE2 3.94Å; Y251-Y268 AromaticContact CD2-CZ 3.53Å; Y251-Y268 AromaticContact CE2-CE2 3.89Å; Y251-Y268 HydrophobicContact CE2-CE2 3.89Å; Y251-Y268 AromaticContact CE2-CZ 3.94Å; T252-Y268 PolarHBondContact N-OH 3.35Å; T252-Y268 PolarHBondContact O-OH 3.27Å; V255-Y268 HydrophobicContact CG1-CD2 3.48Å; V255-Y268 VanDerWaalsContact CG1-CD2 3.48Å; V255-Y268 HydrophobicContact CG1-CE2 3.44Å; V255-Y268 VanDerWaalsContact CG1-CE2 3.44Å; Y263-Y268 WeakPolarHBondContact O-CE2 3.11Å; S264-Y268 WeakPolarHBondContact O-CD2 3.42Å; S264-Y268 PolarHBondContact O-N 3.43Å; L265-Y268 PolarHBondContact O-N 2.75Å; D266-Y268 PolarHBondContact O-N 3.47Å; Y268-L271 PolarHBondContact O-N 2.72Å; Y268-A272 WeakPolarHBondContact O-CB 3.5Å; Y268-A272 PolarHBondContact O-N 2.72Å; Y268-L300 HydrophobicContact CD2-CD1 4.37Å; Y268-L300 HydrophobicContact CG-CD1 4.04Å
269V98.5Very high97.1Very high32 Ų3254.8 Ų54.819%0.19428%0.282CS..Hα-helixtrans-64.8-41.1179.3173.90000111.3L265 A272 D273 A303 L304 R307L265-V269 HydrophobicContact CD1-CG2 4.34Å; L265-V269 HydrophobicContact CG-CG2 4.42Å; L265-V269 WeakPolarHBondContact O-CG2 3.36Å; L265-V269 PolarHBondContact O-N 3.24Å; V269-A272 PolarHBondContact O-N 3.11Å; V269-D273 PolarHBondContact O-N 2.95Å; V269-A303 HydrophobicContact CG2-CB 4.21Å; V269-L304 HydrophobicContact CG2-CD2 4.36Å; V269-R307 HydrophobicContact CG1-CG 4.46Å
270K98.4Very high97.3Very high122 Ų12247.7 Ų47.753%0.5325%0.248SC..Hα-helixtrans-63.9-44.1176.1-77.9173.3175.4164.10112.4D266 A272 D273 E274D266-K270 WeakPolarHBondContact O-CB 3.24Å; D266-K270 VanDerWaalsContact O-CG 3.3Å; D266-K270 WeakPolarHBondContact O-CG 3.2Å; D266-K270 PolarHBondContact O-N 2.77Å; D266-K270 WeakPolarHBondContact OD1-CE 3.46Å; D266-K270 IonicContact OD1-NZ 3.4Å; D266-K270 PolarHBondContact OD1-NZ 3.26Å; D266-K270 WeakPolarHBondContact OD2-CD 3.14Å; D266-K270 WeakPolarHBondContact OD2-CE 3.15Å; D266-K270 IonicContact OD2-NZ 3.89Å; D266-K270 PolarHBondContact OD2-NZ 2.92Å; K270-A272 VanDerWaalsContact C-N 3.32Å; K270-A272 PolarHBondContact O-N 3.02Å; K270-D273 WeakPolarHBondContact O-CB 3.38Å; K270-D273 PolarHBondContact O-N 3.02Å; K270-E274 PolarHBondContact O-N 3.12Å
271L98.5Very high97.8Very high17 Ų1745.9 Ų45.99%0.08924%0.242CC..Hα-helixtrans-63.5-41.2176.8-179.558.4000111.3N226 L228 I249 Y267 Y268 D273 E274 L275N226-L271 HydrophobicContact CB-CD2 3.73Å; L228-L271 HydrophobicContact CD1-CD1 4.28Å; I249-L271 HydrophobicContact CB-CD2 4.34Å; I249-L271 HydrophobicContact CD1-CB 4.31Å; I249-L271 HydrophobicContact CD1-CD2 4.31Å; I249-L271 HydrophobicContact CD1-CG 4.11Å; I249-L271 HydrophobicContact CG1-CD2 3.97Å; I249-L271 HydrophobicContact CG1-CG 4.1Å; I249-L271 HydrophobicContact CG2-CD2 3.62Å; Y267-L271 WeakPolarHBondContact O-CB 3.47Å; Y267-L271 PolarHBondContact O-N 3.13Å; Y267-L271 VanDerWaalsContact O-N 3.07Å; Y268-L271 PolarHBondContact O-N 2.72Å; L271-D273 VanDerWaalsContact C-N 3.32Å; L271-D273 PolarHBondContact O-N 2.77Å; L271-E274 PolarHBondContact O-N 3.35Å; L271-L275 HydrophobicContact CD1-CD1 4.49Å; L271-L275 HydrophobicContact CD1-CG 4.44Å; L271-L275 HydrophobicContact CG-CD1 4.22Å; L271-L275 WeakPolarHBondContact O-CG 3.42Å; L271-L275 PolarHBondContact O-N 3.05Å
272A98.8Very high98.1Very high0 Ų040.2 Ų40.20%022%0.216CC..Hα-helixtrans-59.8-40.9173.800000112.4I249 Y268 V269 K270 E274 L275 V276 L283 L304 F308I249-A272 HydrophobicContact CD1-CB 3.86Å; Y268-A272 WeakPolarHBondContact O-CB 3.5Å; Y268-A272 PolarHBondContact O-N 2.72Å; V269-A272 PolarHBondContact O-N 3.11Å; K270-A272 VanDerWaalsContact C-N 3.32Å; K270-A272 PolarHBondContact O-N 3.02Å; A272-E274 VanDerWaalsContact C-N 3.31Å; A272-E274 PolarHBondContact O-N 3.07Å; A272-L275 PolarHBondContact O-N 3.25Å; A272-V276 WeakPolarHBondContact O-CB 3.35Å; A272-V276 VanDerWaalsContact O-CG2 3.32Å; A272-V276 WeakPolarHBondContact O-CG2 3.34Å; A272-V276 PolarHBondContact O-N 2.69Å; A272-L283 HydrophobicContact CB-CD1 4.19Å; A272-L283 HydrophobicContact CB-CD2 3.71Å; A272-L304 HydrophobicContact CB-CD2 3.56Å; A272-F308 HydrophobicContact CB-CE2 3.66Å; A272-F308 HydrophobicContact CB-CZ 4.2Å
273D98.6Very high98.3Very high30 Ų3037.4 Ų37.416%0.1620%0.204CC..Hα-helixtrans-58.9-42.1176.6-153.778.2000111.5V269 K270 L271 K277 R307 F308V269-D273 PolarHBondContact O-N 2.95Å; K270-D273 WeakPolarHBondContact O-CB 3.38Å; K270-D273 PolarHBondContact O-N 3.02Å; L271-D273 VanDerWaalsContact C-N 3.32Å; L271-D273 PolarHBondContact O-N 2.77Å; D273-K277 WeakPolarHBondContact O-CB 3.27Å; D273-K277 WeakPolarHBondContact O-CG 3.2Å; D273-K277 PolarHBondContact O-N 3.47Å; D273-K277 WeakPolarHBondContact OD2-CE 3.45Å; D273-K277 IonicContact OD2-NZ 2.69Å; D273-K277 PolarHBondContact OD2-NZ 2.7Å; D273-R307 IonicContact OD1-CZ 3.5Å; D273-R307 IonicContact OD1-NE 3.26Å; D273-R307 PolarHBondContact OD1-NE 3.44Å; D273-R307 VanDerWaalsContact OD1-NE 3.14Å; D273-R307 IonicContact OD1-NH2 3.31Å; D273-R307 PolarHBondContact OD1-NH2 2.86Å; D273-R307 IonicContact OD2-NH2 3.09Å; D273-F308 HydrophobicContact CB-CZ 4.16Å
274E98.6Very high98.3Very high82 Ų8237.2 Ų37.238%0.38320%0.203SC..Hα-helixtrans-67.4-40.6176-64.5-59.1116.700112.8L228 K270 L271 A272 K277 A278L228-E274 HydrophobicContact CD1-CB 4.31Å; L228-E274 HydrophobicContact CD2-CB 3.79Å; L228-E274 HydrophobicContact CD2-CG 4.13Å; K270-E274 PolarHBondContact O-N 3.12Å; L271-E274 PolarHBondContact O-N 3.35Å; A272-E274 VanDerWaalsContact C-N 3.31Å; A272-E274 PolarHBondContact O-N 3.07Å; E274-K277 PolarHBondContact O-N 2.95Å; E274-K277 IonicContact OE1-NZ 2.84Å; E274-K277 PolarHBondContact OE1-NZ 2.82Å; E274-A278 WeakPolarHBondContact O-CB 3.43Å; E274-A278 PolarHBondContact O-N 3.46Å
275L98.6Very high98.4Very high0 Ų036.1 Ų36.10%020%0.195CC..Hα-helixtrans-70.4-36.3178.8-64.2173.4000112.7L228 M231 M235 A247 I249 L271 A272 A278 G279 T280 L283L228-L275 HydrophobicContact CD1-CD2 3.63Å; L228-L275 HydrophobicContact CD1-CG 4.42Å; M231-L275 HydrophobicContact CB-CD2 4.39Å; M231-L275 HydrophobicContact CE-CD1 3.76Å; M231-L275 HydrophobicContact CE-CD2 3.67Å; M231-L275 HydrophobicContact CE-CG 4.38Å; M231-L275 HydrophobicContact SD-CD2 4.2Å; M235-L275 HydrophobicContact SD-CD2 3.8Å; A247-L275 HydrophobicContact CB-CB 3.99Å; A247-L275 HydrophobicContact CB-CD1 3.99Å; A247-L275 HydrophobicContact CB-CD2 4.09Å; A247-L275 HydrophobicContact CB-CG 4.24Å; I249-L275 HydrophobicContact CD1-CD1 4.04Å; I249-L275 HydrophobicContact CG1-CD1 3.52Å; L271-L275 HydrophobicContact CD1-CD1 4.49Å; L271-L275 HydrophobicContact CD1-CG 4.44Å; L271-L275 HydrophobicContact CG-CD1 4.22Å; L271-L275 WeakPolarHBondContact O-CG 3.42Å; L271-L275 PolarHBondContact O-N 3.05Å; A272-L275 PolarHBondContact O-N 3.25Å; L275-A278 PolarHBondContact O-N 3.37Å; L275-G279 PolarHBondContact O-N 3.11Å; L275-T280 PolarHBondContact O-N 3.15Å; L275-L283 HydrophobicContact CB-CD1 4.48Å; L275-L283 HydrophobicContact CD1-CD1 4.34Å
276V98.4Very high98.4Very high38 Ų3833.7 Ų33.723%0.2318%0.182CC..Hα-helixtrans-68.9-42.9174.2172.90000110.8A272 A278 G279 T280 F308 V311A272-V276 WeakPolarHBondContact O-CB 3.35Å; A272-V276 VanDerWaalsContact O-CG2 3.32Å; A272-V276 WeakPolarHBondContact O-CG2 3.34Å; A272-V276 PolarHBondContact O-N 2.69Å; V276-A278 PolarHBondContact O-N 3.33Å; V276-G279 PolarHBondContact O-N 2.86Å; V276-T280 HydrophobicContact CG2-CG2 4.11Å; V276-F308 HydrophobicContact CB-CD1 4.18Å; V276-F308 HydrophobicContact CB-CE1 3.91Å; V276-F308 HydrophobicContact CB-CZ 4.45Å; V276-F308 HydrophobicContact CG1-CD1 3.93Å; V276-F308 HydrophobicContact CG1-CE1 4Å; V276-F308 HydrophobicContact CG2-CD1 3.88Å; V276-F308 HydrophobicContact CG2-CD2 4.43Å; V276-F308 HydrophobicContact CG2-CE1 3.87Å; V276-F308 HydrophobicContact CG2-CE2 4.43Å; V276-F308 HydrophobicContact CG2-CG 4.17Å; V276-F308 HydrophobicContact CG2-CZ 4.17Å; V276-V311 HydrophobicContact CG1-CG2 4.23Å; V276-V311 HydrophobicContact CG2-CG2 4.4Å
277K98.3Very high98.5Very high134 Ų13429.7 Ų29.758%0.58316%0.161SC*.Hα-helixtrans-59.1-35172-75.4170.2-165.7155.80112.7D273 E274 G279D273-K277 WeakPolarHBondContact O-CB 3.27Å; D273-K277 WeakPolarHBondContact O-CG 3.2Å; D273-K277 PolarHBondContact O-N 3.47Å; D273-K277 WeakPolarHBondContact OD2-CE 3.45Å; D273-K277 IonicContact OD2-NZ 2.69Å; D273-K277 PolarHBondContact OD2-NZ 2.7Å; E274-K277 PolarHBondContact O-N 2.95Å; E274-K277 IonicContact OE1-NZ 2.84Å; E274-K277 PolarHBondContact OE1-NZ 2.82Å; K277-G279 PolarHBondContact O-N 2.99Å
278A97.9Very high98.3Very high47 Ų4728.7 Ų28.739%0.38816%0.157SC..THydrogen-bonded Turntrans-73.4-2.1176.400000114L232 M235 E274 L275 V276L232-A278 HydrophobicContact CD2-CB 3.36Å; M235-A278 HydrophobicContact CE-CB 3.76Å; E274-A278 WeakPolarHBondContact O-CB 3.43Å; E274-A278 PolarHBondContact O-N 3.46Å; L275-A278 PolarHBondContact O-N 3.37Å; V276-A278 PolarHBondContact O-N 3.33Å
279G97.1Very high98.2Very high45 Ų4528.7 Ų28.746%0.46416%0.157SC..THydrogen-bonded Turntrans87.433.2173.100000114.5L275 V276 K277 H281L275-G279 PolarHBondContact O-N 3.11Å; V276-G279 PolarHBondContact O-N 2.86Å; K277-G279 PolarHBondContact O-N 2.99Å; G279-H281 PolarHBondContact O-N 2.82Å
280T98.6Very high98.2Very high13 Ų1327.3 Ų27.38%0.0815%0.15CC..  trans-61.5137.5169.3-160.90000111.1V245 A247 L275 V276 I282 L283V245-T280 PolarHBondContact O-OG1 3.23Å; A247-T280 HydrophobicContact CB-CG2 4.32Å; A247-T280 WeakPolarHBondContact CB-OG1 3.45Å; A247-T280 PolarHBondContact N-OG1 3.18Å; L275-T280 PolarHBondContact O-N 3.15Å; V276-T280 HydrophobicContact CG2-CG2 4.11Å; T280-I282 PolarHBondContact OG1-O 3.42Å; T280-L283 HydrophobicContact CG2-CB 4.5Å
281H98.8Very high98.1Very high31 Ų3121.7 Ų21.714%0.14413%0.125CC..SBendtrans-79.7-33.8174.1-56.993.6000110.9P95 E96 A99 V244 V245 G279 P312P95-H281 WeakPolarHBondContact CB-NE2 3.14Å; E96-H281 IonicContact OE1-NE2 3.39Å; A99-H281 HydrophobicContact CB-CB 4.15Å; A99-H281 WeakPolarHBondContact CB-O 3.28Å; V244-H281 HydrophobicContact CG1-CB 3.96Å; V245-H281 WeakPolarHBondContact CB-ND1 3.04Å; V245-H281 PolarHBondContact N-ND1 2.94Å; V245-H281 WeakPolarHBondContact O-CB 3.36Å; V245-H281 PolarHBondContact O-N 3.05Å; G279-H281 PolarHBondContact O-N 2.82Å; H281-P312 WeakPolarHBondContact O-CD 3.38Å
282I98.9Very high98Very high0 Ų021 Ų210%012%0.122CC..EExtended strand (participates in β ladder)trans-135.8133.4-178.1-58.9-179000107.8F98 F147 V244 V245 E246 A247 T280 P312 H314F98-I282 HydrophobicContact CD1-CD1 4.42Å; F98-I282 HydrophobicContact CE1-CD1 3.85Å; F147-I282 HydrophobicContact CE2-CD1 3.55Å; F147-I282 HydrophobicContact CZ-CD1 3.44Å; F147-I282 VanDerWaalsContact CZ-CD1 3.44Å; V244-I282 HydrophobicContact CG1-CD1 4.11Å; V244-I282 HydrophobicContact CG1-CG1 4.44Å; V245-I282 PolarHBondContact O-N 3.32Å; E246-I282 WeakPolarHBondContact CA-O 3.32Å; E246-I282 HydrophobicContact CB-CB 4.12Å; E246-I282 HydrophobicContact CB-CG2 4.48Å; E246-I282 HydrophobicContact CG-CB 4.04Å; E246-I282 HydrophobicContact CG-CG2 3.88Å; A247-I282 PolarHBondContact N-O 2.84Å; A247-I282 VanDerWaalsContact N-O 3.09Å; T280-I282 PolarHBondContact OG1-O 3.42Å; I282-P312 HydrophobicContact CB-CB 4.47Å; I282-P312 HydrophobicContact CG1-CB 4.08Å; I282-P312 HydrophobicContact CG1-CG 4.24Å; I282-P312 HydrophobicContact CG2-CB 4.18Å; I282-H314 HydrophobicContact CG2-CB 3.91Å
283L98.9Very high98Very high1 Ų124.2 Ų24.21%0.00514%0.136CC..EExtended strand (participates in β ladder)trans-96.9129.7173.8-178.967.5000109.1I249 A272 L275 T280 L304 F308 V311 P312 I313 H314I249-L283 HydrophobicContact CD1-CD1 4.14Å; A272-L283 HydrophobicContact CB-CD1 4.19Å; A272-L283 HydrophobicContact CB-CD2 3.71Å; L275-L283 HydrophobicContact CB-CD1 4.48Å; L275-L283 HydrophobicContact CD1-CD1 4.34Å; T280-L283 HydrophobicContact CG2-CB 4.5Å; L283-L304 HydrophobicContact CD2-CD1 4.37Å; L283-L304 HydrophobicContact CD2-CD2 4.09Å; L283-F308 HydrophobicContact CD2-CD2 4.23Å; L283-F308 HydrophobicContact CD2-CE2 4.49Å; L283-V311 HydrophobicContact CB-CG1 3.95Å; L283-P312 PolarHBondContact N-O 3.12Å; L283-I313 WeakPolarHBondContact O-CA 3.44Å; L283-H314 PolarHBondContact O-N 3.31Å
284S98.8Very high97.9Very high0 Ų025.2 Ų25.20%014%0.144CC..EExtended strand (participates in β ladder)trans-121.6138.7-175.2-175.60000112.5E246 A247 A248 I249 H314E246-S284 WeakPolarHBondContact OE1-CB 3.4Å; E246-S284 PolarHBondContact OE1-OG 3.13Å; A247-S284 PolarHBondContact O-N 2.86Å; A248-S284 CarbonylContact C-O 3.18Å; A248-S284 WeakPolarHBondContact CA-O 3.44Å; I249-S284 PolarHBondContact N-O 3.01Å; S284-H314 CarbonylContact C-O 3.36Å; S284-H314 WeakPolarHBondContact CA-O 3.2Å
285I98.8Very high97.9Very high0 Ų027 Ų270%015%0.152CC..EExtended strand (participates in β ladder)trans-106.5114.5168.6-59.4-55.8000108I249 L292 L300 I301 L304 H314 V315 H316I249-I285 HydrophobicContact CB-CD1 4.01Å; I249-I285 HydrophobicContact CD1-CD1 4.19Å; I285-L292 HydrophobicContact CG2-CD1 3.96Å; I285-L300 HydrophobicContact CD1-CD2 4.33Å; I285-L300 HydrophobicContact CG1-CD2 4.27Å; I285-L300 HydrophobicContact CG2-CD2 3.96Å; I285-I301 HydrophobicContact CG1-CD1 3.97Å; I285-L304 HydrophobicContact CD1-CD1 3.7Å; I285-L304 HydrophobicContact CG1-CD1 3.85Å; I285-H314 PolarHBondContact N-O 3.48Å; I285-V315 HydrophobicContact CB-CG1 4.43Å; I285-H316 PolarHBondContact O-N 3.46Å
286K98.5Very high97.8Very high6 Ų627 Ų273%0.02615%0.152CC..EExtended strand (participates in β ladder)trans-102.394-180-176.2172.2175.554.30110.9L187 A248 I249 S250 Y251 M288 H316L187-K286 HydrophobicContact CD1-CD 4.23Å; A248-K286 HydrophobicContact CB-CB 4.38Å; I249-K286 PolarHBondContact O-N 3.45Å; S250-K286 CarbonylContact C-O 3.35Å; S250-K286 WeakPolarHBondContact CA-O 3.49Å; Y251-K286 PolarHBondContact N-O 3.41Å; K286-M288 PolarHBondContact O-N 2.94Å; K286-H316 PolarHBondContact NZ-CD2 3.44Å; K286-H316 PolarHBondContact NZ-CE1 2.84Å; K286-H316 PolarHBondContact NZ-NE2 3.35Å
287D98.3Very high97.8Very high0 Ų025.2 Ų25.20%014%0.141CC..EExtended strand (participates in β ladder)trans-87.779.8170.2174.524.6000111.3Y251 A289 G290 L291 L292 H316 T317 H318Y251-D287 HydrophobicContact CD1-CB 4.3Å; D287-A289 PolarHBondContact O-N 2.88Å; D287-A289 VanDerWaalsContact O-N 3.13Å; D287-G290 PolarHBondContact O-N 3.34Å; D287-G290 PolarHBondContact OD1-N 3.3Å; D287-G290 VanDerWaalsContact OD2-C 3.29Å; D287-G290 WeakPolarHBondContact OD2-CA 3.4Å; D287-L291 PolarHBondContact OD1-N 2.71Å; D287-L291 PolarHBondContact OD2-N 3.22Å; D287-L292 HydrophobicContact CB-CB 4.45Å; D287-L292 HydrophobicContact CB-CD1 3.76Å; D287-L292 HydrophobicContact CB-CG 4Å; D287-L292 WeakPolarHBondContact OD2-CB 3.45Å; D287-L292 PolarHBondContact OD2-N 3.05Å; D287-H316 WeakPolarHBondContact CB-O 3.44Å; D287-H316 PolarHBondContact N-O 3.11Å; D287-T317 WeakPolarHBondContact O-CA 3.45Å; D287-T317 PolarHBondContact OD2-OG1 3.49Å; D287-H318 PolarHBondContact O-CD2 3.48Å; D287-H318 PolarHBondContact O-N 2.91Å
288M95.4Very high97.8Very high4 Ų423.2 Ų23.22%0.0213%0.132CC..THydrogen-bonded Turntrans-65.3-12-17564-79.7179.900115.5Y251 K286 H318 P412 G413 I450 K451 V452Y251-M288 WeakPolarHBondContact O-CE 3.46Å; Y251-M288 VanDerWaalsContact O-SD 3.37Å; K286-M288 PolarHBondContact O-N 2.94Å; M288-H318 PolarHBondContact O-CD2 3.2Å; M288-H318 PolarHBondContact O-NE2 3.28Å; M288-P412 HydrophobicContact CB-CB 4.32Å; M288-P412 HydrophobicContact CG-CB 4.13Å; M288-P412 HydrophobicContact CG-CG 3.97Å; M288-P412 WeakPolarHBondContact O-CA 3.48Å; M288-P412 WeakPolarHBondContact O-CB 3.4Å; M288-G413 PolarHBondContact O-N 2.6Å; M288-I450 HydrophobicContact CE-CG2 3.94Å; M288-K451 VanDerWaalsContact CE-O 3.22Å; M288-K451 WeakPolarHBondContact CE-O 3.38Å; M288-K451 WeakPolarHBondContact CG-O 3.4Å; M288-V452 HydrophobicContact CB-CB 4.49Å; M288-V452 HydrophobicContact CB-CG2 4.2Å; M288-V452 HydrophobicContact CE-CB 4.49Å; M288-V452 HydrophobicContact CG-CB 3.94Å; M288-V452 HydrophobicContact CG-CG2 4.2Å; M288-V452 HydrophobicContact SD-CB 4.29Å
289A96.3Very high97.8Very high0 Ų024.5 Ų24.50%013%0.132CC..THydrogen-bonded Turntrans-114.2-15.4-17800000113.5D287 L291 T320 V406D287-A289 PolarHBondContact O-N 2.88Å; D287-A289 VanDerWaalsContact O-N 3.13Å; A289-L291 HydrophobicContact CB-CD1 4.21Å; A289-L291 HydrophobicContact CB-CD2 4.14Å; A289-L291 HydrophobicContact CB-CG 3.86Å; A289-T320 PolarHBondContact O-OG1 3.33Å; A289-V406 HydrophobicContact CB-CG2 4.19Å; A289-V406 WeakPolarHBondContact O-CG2 3.5Å
290G97.2Very high97.9Very high4 Ų422.3 Ų22.34%0.04111%0.11CC..SBendtrans82.142.5-174.900000112.1D287 H318D287-G290 PolarHBondContact O-N 3.34Å; D287-G290 PolarHBondContact OD1-N 3.3Å; D287-G290 VanDerWaalsContact OD2-C 3.29Å; D287-G290 WeakPolarHBondContact OD2-CA 3.4Å; G290-H318 WeakPolarHBondContact CA-O 3.35Å
291L97.6Very high97.9Very high4 Ų421.7 Ų21.72%0.02111%0.107CC..  trans-92.1-20.7-178.8-55.5179.5000112.9Y251 D287 A289 K293 V406 Y407 E410Y251-L291 HydrophobicContact CD1-CB 4.06Å; Y251-L291 HydrophobicContact CE1-CB 3.8Å; D287-L291 PolarHBondContact OD1-N 2.71Å; D287-L291 PolarHBondContact OD2-N 3.22Å; A289-L291 HydrophobicContact CB-CD1 4.21Å; A289-L291 HydrophobicContact CB-CD2 4.14Å; A289-L291 HydrophobicContact CB-CG 3.86Å; L291-K293 PolarHBondContact O-N 3.05Å; L291-V406 HydrophobicContact CD2-CG2 4.28Å; L291-V406 WeakPolarHBondContact CD2-O 3.43Å; L291-Y407 HydrophobicContact CD2-CD1 4.19Å; L291-E410 HydrophobicContact CD1-CB 4.09Å; L291-E410 HydrophobicContact CD1-CG 3.8Å; L291-E410 HydrophobicContact CD2-CB 4.4Å; L291-E410 HydrophobicContact CD2-CG 3.99Å
292L96.3Very high97.9Very high3 Ų321 Ų212%0.01611%0.108CC..  trans-67.3107.1178.6-81.8173.5000110.3Y251 I285 D287 L300 V315 A327Y251-L292 HydrophobicContact CD1-CD2 4.07Å; Y251-L292 HydrophobicContact CD1-CG 3.79Å; Y251-L292 HydrophobicContact CD2-CD2 3.91Å; Y251-L292 HydrophobicContact CD2-CG 4.32Å; Y251-L292 HydrophobicContact CE1-CD2 3.74Å; Y251-L292 HydrophobicContact CE1-CG 3.81Å; Y251-L292 HydrophobicContact CE2-CD2 3.54Å; Y251-L292 HydrophobicContact CE2-CG 4.31Å; Y251-L292 HydrophobicContact CG-CD2 4.16Å; Y251-L292 HydrophobicContact CG-CG 4.06Å; Y251-L292 VanDerWaalsContact CZ-CD2 3.45Å; I285-L292 HydrophobicContact CG2-CD1 3.96Å; D287-L292 HydrophobicContact CB-CB 4.45Å; D287-L292 HydrophobicContact CB-CD1 3.76Å; D287-L292 HydrophobicContact CB-CG 4Å; D287-L292 WeakPolarHBondContact OD2-CB 3.45Å; D287-L292 PolarHBondContact OD2-N 3.05Å; L292-L300 HydrophobicContact CD2-CD2 4.24Å; L292-V315 HydrophobicContact CD1-CG1 4.19Å; L292-A327 WeakPolarHBondContact O-CB 3.25Å
293K97.2Very high97.9Very high67 Ų6722.3 Ų22.329%0.29112%0.119SC..  trans-78.2159168.1-64.9176-69.3176.20110.2D254 L291 E295 G296 S297 Y407D254-K293 WeakPolarHBondContact OD1-CE 3.32Å; D254-K293 IonicContact OD1-NZ 2.83Å; D254-K293 WeakPolarHBondContact OD2-CE 3.4Å; D254-K293 IonicContact OD2-NZ 2.89Å; D254-K293 PolarHBondContact OD2-NZ 3.42Å; L291-K293 PolarHBondContact O-N 3.05Å; K293-E295 VanDerWaalsContact C-N 3.29Å; K293-E295 PolarHBondContact O-N 2.95Å; K293-G296 PolarHBondContact O-N 3.44Å; K293-G296 VanDerWaalsContact O-N 3.16Å; K293-S297 WeakPolarHBondContact O-CB 3.33Å; K293-S297 PolarHBondContact O-N 3.23Å; K293-S297 PolarHBondContact O-OG 3.14Å; K293-Y407 HydrophobicContact CG-CE1 4.05Å
294P97.9Very high97.9Very high50 Ų5022.3 Ų22.333%0.32512%0.118SC..Hα-helixtrans-52.4-41.8177.4-30.436.7000114.4S297 K298 A326 A330P294-S297 WeakPolarHBondContact O-CB 3.34Å; P294-S297 PolarHBondContact O-N 2.8Å; P294-K298 WeakPolarHBondContact O-CG 3.42Å; P294-K298 PolarHBondContact O-N 3.39Å; P294-A326 HydrophobicContact CG-CB 4.01Å; P294-A330 HydrophobicContact CB-CB 3.95Å
295E97.2Very high97.9Very high121 Ų12123.5 Ų23.557%0.56512%0.123SC*.Hα-helixtrans-69.6-43.9179.2-166.168.5175.100112.4K293 S297 K298 L299K293-E295 VanDerWaalsContact C-N 3.29Å; K293-E295 PolarHBondContact O-N 2.95Å; E295-S297 PolarHBondContact O-N 3.27Å; E295-K298 PolarHBondContact O-N 2.85Å; E295-L299 WeakPolarHBondContact O-CG 3.36Å; E295-L299 PolarHBondContact O-N 3.43Å
296G97.6Very high97.9Very high0 Ų030.3 Ų30.30%016%0.159CC..Hα-helixtrans-62.4-34.6174.500000112.2K293 L299 L300K293-G296 PolarHBondContact O-N 3.44Å; K293-G296 VanDerWaalsContact O-N 3.16Å; G296-L299 PolarHBondContact O-N 3.17Å; G296-L300 WeakPolarHBondContact O-CB 3.36Å; G296-L300 PolarHBondContact O-N 3.36Å
297S98.3Very high97.9Very high0 Ų036.8 Ų36.80%018%0.183CC..Hα-helixtrans-61.7-49.5174.1-58.90000111.4K293 P294 E295 L299 L300 I301 C331K293-S297 WeakPolarHBondContact O-CB 3.33Å; K293-S297 PolarHBondContact O-N 3.23Å; K293-S297 PolarHBondContact O-OG 3.14Å; P294-S297 WeakPolarHBondContact O-CB 3.34Å; P294-S297 PolarHBondContact O-N 2.8Å; E295-S297 PolarHBondContact O-N 3.27Å; S297-L299 VanDerWaalsContact C-N 3.35Å; S297-L299 PolarHBondContact O-N 2.98Å; S297-L300 PolarHBondContact O-N 2.9Å; S297-I301 VanDerWaalsContact O-CB 3.28Å; S297-I301 WeakPolarHBondContact O-CB 3.35Å; S297-I301 VanDerWaalsContact O-CG1 3.3Å; S297-I301 WeakPolarHBondContact O-CG1 3.49Å; S297-I301 PolarHBondContact O-N 3.21Å; S297-C331 VanDerWaalsContact CB-SG 3.52Å
298K98.6Very high97.9Very high91 Ų9137.5 Ų37.540%0.39619%0.187SC..Hα-helixtrans-61.5-43.3178.5-71.1-179.4179.3-166.80112.2P294 E295 G302 A330 E333P294-K298 WeakPolarHBondContact O-CG 3.42Å; P294-K298 PolarHBondContact O-N 3.39Å; E295-K298 PolarHBondContact O-N 2.85Å; K298-G302 WeakPolarHBondContact O-CA 3.34Å; K298-G302 PolarHBondContact O-N 2.91Å; K298-A330 HydrophobicContact CG-CB 4.15Å; K298-E333 WeakPolarHBondContact CE-OE2 3.47Å; K298-E333 IonicContact NZ-OE2 2.64Å; K298-E333 PolarHBondContact NZ-OE2 2.86Å
299L98.4Very high98Very high74 Ų7440.5 Ų40.539%0.38721%0.207SC..Hα-helixtrans-63.8-52178.6-69.7171.9000112.1E295 G296 S297 A303E295-L299 WeakPolarHBondContact O-CG 3.36Å; E295-L299 PolarHBondContact O-N 3.43Å; G296-L299 PolarHBondContact O-N 3.17Å; S297-L299 VanDerWaalsContact C-N 3.35Å; S297-L299 PolarHBondContact O-N 2.98Å; L299-A303 VanDerWaalsContact O-CB 3.29Å; L299-A303 WeakPolarHBondContact O-CB 3.43Å; L299-A303 PolarHBondContact O-N 3.12Å; L299-A303 VanDerWaalsContact O-N 3.13Å
300L98.8Very high98.1Very high0 Ų047 Ų470%024%0.241CC..Hα-helixtrans-68-53.3-176.2178.358.8000111.7Y251 V255 L265 Y268 I285 L292 G296 S297 G302 A303 L304Y251-L300 HydrophobicContact CD2-CD2 3.84Å; Y251-L300 HydrophobicContact CE2-CD2 3.98Å; V255-L300 HydrophobicContact CG2-CB 4.32Å; L265-L300 HydrophobicContact CD1-CB 4.36Å; L265-L300 HydrophobicContact CD1-CD1 3.84Å; Y268-L300 HydrophobicContact CD2-CD1 4.37Å; Y268-L300 HydrophobicContact CG-CD1 4.04Å; I285-L300 HydrophobicContact CD1-CD2 4.33Å; I285-L300 HydrophobicContact CG1-CD2 4.27Å; I285-L300 HydrophobicContact CG2-CD2 3.96Å; L292-L300 HydrophobicContact CD2-CD2 4.24Å; G296-L300 WeakPolarHBondContact O-CB 3.36Å; G296-L300 PolarHBondContact O-N 3.36Å; S297-L300 PolarHBondContact O-N 2.9Å; L300-G302 PolarHBondContact O-N 2.68Å; L300-A303 PolarHBondContact O-N 3.21Å; L300-L304 HydrophobicContact CD1-CD1 3.96Å; L300-L304 HydrophobicContact CD1-CG 4.25Å; L300-L304 HydrophobicContact CG-CD1 4.09Å; L300-L304 VanDerWaalsContact O-CG 3.29Å; L300-L304 WeakPolarHBondContact O-CG 3.38Å; L300-L304 PolarHBondContact O-N 2.86Å
301I98.8Very high98.2Very high0 Ų047.9 Ų47.90%025%0.246CC..Hα-helixtrans-68.6-38.2-175.1-58-51.6000110.9I285 S297 L304 R305 I313 V315 C331 A334 A336I285-I301 HydrophobicContact CG1-CD1 3.97Å; S297-I301 VanDerWaalsContact O-CB 3.28Å; S297-I301 WeakPolarHBondContact O-CB 3.35Å; S297-I301 VanDerWaalsContact O-CG1 3.3Å; S297-I301 WeakPolarHBondContact O-CG1 3.49Å; S297-I301 PolarHBondContact O-N 3.21Å; I301-L304 HydrophobicContact CD1-CD1 4.46Å; I301-L304 PolarHBondContact O-N 3.11Å; I301-R305 WeakPolarHBondContact O-CB 3.36Å; I301-R305 PolarHBondContact O-N 3.47Å; I301-I313 HydrophobicContact CD1-CG2 4.2Å; I301-I313 HydrophobicContact CG2-CG2 4.34Å; I301-V315 HydrophobicContact CD1-CG2 3.51Å; I301-V315 HydrophobicContact CG1-CG2 4.07Å; I301-C331 HydrophobicContact CG1-CB 4.17Å; I301-A334 HydrophobicContact CB-CB 3.87Å; I301-A334 HydrophobicContact CG2-CB 3.91Å; I301-A336 HydrophobicContact CG2-CB 4.09Å
302G98.8Very high98.2Very high16 Ų1647.9 Ų47.917%0.16525%0.246CC..Hα-helixtrans-60.3-48174.400000112K298 L300 L304 R305 D306K298-G302 WeakPolarHBondContact O-CA 3.34Å; K298-G302 PolarHBondContact O-N 2.91Å; L300-G302 PolarHBondContact O-N 2.68Å; G302-L304 VanDerWaalsContact C-N 3.32Å; G302-L304 PolarHBondContact O-N 2.55Å; G302-R305 PolarHBondContact O-N 2.9Å; G302-D306 WeakPolarHBondContact O-CB 3.33Å; G302-D306 PolarHBondContact O-N 3.28Å
303A98.8Very high98.4Very high28 Ų2847.7 Ų47.723%0.23125%0.245CC..Hα-helixtrans-61.7-39177.600000112.7L265 V269 L299 L300 R307L265-A303 HydrophobicContact CD1-CB 4.04Å; L265-A303 HydrophobicContact CD2-CB 4.24Å; L265-A303 HydrophobicContact CG-CB 4.46Å; V269-A303 HydrophobicContact CG2-CB 4.21Å; L299-A303 VanDerWaalsContact O-CB 3.29Å; L299-A303 WeakPolarHBondContact O-CB 3.43Å; L299-A303 PolarHBondContact O-N 3.12Å; L299-A303 VanDerWaalsContact O-N 3.13Å; L300-A303 PolarHBondContact O-N 3.21Å; A303-R307 VanDerWaalsContact O-CB 3.32Å; A303-R307 WeakPolarHBondContact O-CB 3.35Å; A303-R307 PolarHBondContact O-N 3.42Å; A303-R307 VanDerWaalsContact O-N 3.1Å
304L98.8Very high98.4Very high0 Ų044.5 Ų44.50%023%0.231CC..Hα-helixtrans-68.3-41.8176.2-68.3173.6000111.9V269 A272 L283 I285 L300 I301 G302 R307 F308 I313V269-L304 HydrophobicContact CG2-CD2 4.36Å; A272-L304 HydrophobicContact CB-CD2 3.56Å; L283-L304 HydrophobicContact CD2-CD1 4.37Å; L283-L304 HydrophobicContact CD2-CD2 4.09Å; I285-L304 HydrophobicContact CD1-CD1 3.7Å; I285-L304 HydrophobicContact CG1-CD1 3.85Å; L300-L304 HydrophobicContact CD1-CD1 3.96Å; L300-L304 HydrophobicContact CD1-CG 4.25Å; L300-L304 HydrophobicContact CG-CD1 4.09Å; L300-L304 VanDerWaalsContact O-CG 3.29Å; L300-L304 WeakPolarHBondContact O-CG 3.38Å; L300-L304 PolarHBondContact O-N 2.86Å; I301-L304 HydrophobicContact CD1-CD1 4.46Å; I301-L304 PolarHBondContact O-N 3.11Å; G302-L304 VanDerWaalsContact C-N 3.32Å; G302-L304 PolarHBondContact O-N 2.55Å; L304-R307 PolarHBondContact O-N 3.19Å; L304-F308 HydrophobicContact CD2-CD2 4.44Å; L304-F308 HydrophobicContact CD2-CE2 4.19Å; L304-F308 WeakPolarHBondContact O-CD2 3.18Å; L304-F308 PolarHBondContact O-N 2.83Å; L304-I313 HydrophobicContact CB-CD1 3.93Å
305R98.7Very high98.5Very high26 Ų2642.1 Ų42.110%0.09822%0.216CC..Hα-helixtrans-63.7-44.2176.7175.853.564.6-1563.9111.7I301 G302 R307 F308 P309 V311 I313 G335 D337I301-R305 WeakPolarHBondContact O-CB 3.36Å; I301-R305 PolarHBondContact O-N 3.47Å; G302-R305 PolarHBondContact O-N 2.9Å; R305-R307 VanDerWaalsContact C-N 3.27Å; R305-R307 PolarHBondContact O-N 3.22Å; R305-F308 PolarHBondContact NH1-O 3.22Å; R305-F308 VanDerWaalsContact NH1-O 3.15Å; R305-F308 CarbonylContact O-C 3.5Å; R305-F308 PolarHBondContact O-N 3.15Å; R305-P309 PolarHBondContact NH1-O 2.75Å; R305-P309 VanDerWaalsContact NH1-O 3.11Å; R305-P309 WeakPolarHBondContact O-CA 3.35Å; R305-V311 PolarHBondContact NH1-O 2.65Å; R305-I313 HydrophobicContact CB-CD1 4Å; R305-G335 PolarHBondContact NE-O 2.93Å; R305-G335 VanDerWaalsContact NE-O 3.07Å; R305-G335 PolarHBondContact NH2-O 3.02Å; R305-D337 IonicContact CZ-OD2 3.81Å; R305-D337 VanDerWaalsContact NH2-CG 3.31Å; R305-D337 IonicContact NH2-OD1 2.69Å; R305-D337 PolarHBondContact NH2-OD1 2.92Å; R305-D337 IonicContact NH2-OD2 3.66Å; R305-D337 PolarHBondContact NH2-OD2 3.24Å
306D98.6Very high98.6Very high143 Ų14336.4 Ų36.477%0.76519%0.189SC*.Hα-helixtrans-61.2-38.9177-74.2-14.7000111.5G302G302-D306 WeakPolarHBondContact O-CB 3.33Å; G302-D306 PolarHBondContact O-N 3.28Å
307R98.6Very high98.6Very high141 Ų14136.4 Ų36.453%0.53219%0.189SC..Hα-helixtrans-75.5-36.5179.4-175.961.9176.8-179.71.2113V269 D273 A303 L304 R305V269-R307 HydrophobicContact CG1-CG 4.46Å; D273-R307 IonicContact OD1-CZ 3.5Å; D273-R307 IonicContact OD1-NE 3.26Å; D273-R307 PolarHBondContact OD1-NE 3.44Å; D273-R307 VanDerWaalsContact OD1-NE 3.14Å; D273-R307 IonicContact OD1-NH2 3.31Å; D273-R307 PolarHBondContact OD1-NH2 2.86Å; D273-R307 IonicContact OD2-NH2 3.09Å; A303-R307 VanDerWaalsContact O-CB 3.32Å; A303-R307 WeakPolarHBondContact O-CB 3.35Å; A303-R307 PolarHBondContact O-N 3.42Å; A303-R307 VanDerWaalsContact O-N 3.1Å; L304-R307 PolarHBondContact O-N 3.19Å; R305-R307 VanDerWaalsContact C-N 3.27Å; R305-R307 PolarHBondContact O-N 3.22Å
308F98.5Very high98.6Very high16 Ų1636.7 Ų36.77%0.0719%0.19CC..  trans-128.973.9-173.9-49.9-68.9000111A272 D273 V276 L283 L304 R305 D310 V311A272-F308 HydrophobicContact CB-CE2 3.66Å; A272-F308 HydrophobicContact CB-CZ 4.2Å; D273-F308 HydrophobicContact CB-CZ 4.16Å; V276-F308 HydrophobicContact CB-CD1 4.18Å; V276-F308 HydrophobicContact CB-CE1 3.91Å; V276-F308 HydrophobicContact CB-CZ 4.45Å; V276-F308 HydrophobicContact CG1-CD1 3.93Å; V276-F308 HydrophobicContact CG1-CE1 4Å; V276-F308 HydrophobicContact CG2-CD1 3.88Å; V276-F308 HydrophobicContact CG2-CD2 4.43Å; V276-F308 HydrophobicContact CG2-CE1 3.87Å; V276-F308 HydrophobicContact CG2-CE2 4.43Å; V276-F308 HydrophobicContact CG2-CG 4.17Å; V276-F308 HydrophobicContact CG2-CZ 4.17Å; L283-F308 HydrophobicContact CD2-CD2 4.23Å; L283-F308 HydrophobicContact CD2-CE2 4.49Å; L304-F308 HydrophobicContact CD2-CD2 4.44Å; L304-F308 HydrophobicContact CD2-CE2 4.19Å; L304-F308 WeakPolarHBondContact O-CD2 3.18Å; L304-F308 PolarHBondContact O-N 2.83Å; R305-F308 PolarHBondContact NH1-O 3.22Å; R305-F308 VanDerWaalsContact NH1-O 3.15Å; R305-F308 CarbonylContact O-C 3.5Å; R305-F308 PolarHBondContact O-N 3.15Å; F308-D310 VanDerWaalsContact C-N 3.26Å; F308-D310 PolarHBondContact O-N 2.8Å; F308-V311 HydrophobicContact CB-CB 4.02Å; F308-V311 HydrophobicContact CB-CG2 4.03Å; F308-V311 PolarHBondContact O-N 2.93Å
309P98Very high98.5Very high67 Ų6733.4 Ų33.444%0.43518%0.177SC..THydrogen-bonded Turntrans-64.2-28.7-173.424-34.6000113.9R103 R305R103-P309 PolarHBondContact NE-O 2.84Å; R305-P309 PolarHBondContact NH1-O 2.75Å; R305-P309 VanDerWaalsContact NH1-O 3.11Å; R305-P309 WeakPolarHBondContact O-CA 3.35Å
310D97.8Very high98.3Very high135 Ų13530 Ų3072%0.72216%0.159SC*.THydrogen-bonded Turntrans-99.3-12.3-173.8-57.8-50.7000114F308F308-D310 VanDerWaalsContact C-N 3.26Å; F308-D310 PolarHBondContact O-N 2.8Å
311V98.6Very high98.1Very high24 Ų2431.1 Ų31.115%0.14517%0.169CC..SBendtrans-86.7128.1-178.8-178.20000109.1V276 L283 R305 F308 I313V276-V311 HydrophobicContact CG1-CG2 4.23Å; V276-V311 HydrophobicContact CG2-CG2 4.4Å; L283-V311 HydrophobicContact CB-CG1 3.95Å; R305-V311 PolarHBondContact NH1-O 2.65Å; F308-V311 HydrophobicContact CB-CB 4.02Å; F308-V311 HydrophobicContact CB-CG2 4.03Å; F308-V311 PolarHBondContact O-N 2.93Å; V311-I313 PolarHBondContact O-N 3.3Å
312P98.9Very high97.9Very high3 Ų333.9 Ų33.92%0.01920%0.197CC..  trans-58.2135.5170.3-24.632.4000112.3A99 V102 R103 H281 I282 L283 D337A99-P312 HydrophobicContact CB-CG 4.1Å; A99-P312 WeakPolarHBondContact O-CG 3.48Å; V102-P312 HydrophobicContact CB-CG 4.35Å; V102-P312 HydrophobicContact CG1-CB 3.92Å; V102-P312 HydrophobicContact CG1-CG 4.26Å; R103-P312 HydrophobicContact CB-CG 4.14Å; H281-P312 WeakPolarHBondContact O-CD 3.38Å; I282-P312 HydrophobicContact CB-CB 4.47Å; I282-P312 HydrophobicContact CG1-CB 4.08Å; I282-P312 HydrophobicContact CG1-CG 4.24Å; I282-P312 HydrophobicContact CG2-CB 4.18Å; L283-P312 PolarHBondContact N-O 3.12Å; P312-D337 WeakPolarHBondContact CA-OD2 3.44Å
313I98.9Very high97.8Very high0 Ų034.2 Ų34.20%020%0.198CC..EExtended strand (participates in β ladder)trans-110.8119.4176.5-61.6174.6000109.1L283 I301 L304 R305 V311 V315 A336 D337 V338L283-I313 WeakPolarHBondContact O-CA 3.44Å; I301-I313 HydrophobicContact CD1-CG2 4.2Å; I301-I313 HydrophobicContact CG2-CG2 4.34Å; L304-I313 HydrophobicContact CB-CD1 3.93Å; R305-I313 HydrophobicContact CB-CD1 4Å; V311-I313 PolarHBondContact O-N 3.3Å; I313-V315 HydrophobicContact CG2-CG2 4.2Å; I313-A336 HydrophobicContact CG2-CB 4.44Å; I313-D337 PolarHBondContact N-OD2 2.73Å; I313-D337 PolarHBondContact O-N 3.03Å; I313-V338 PolarHBondContact O-N 3.02Å
314H98.9Very high97.7Very high0 Ų033 Ų330%019%0.189CC..EExtended strand (participates in β ladder)trans-108.7128.1176.6-165165.6000109.8M111 F147 R220 E246 I282 L283 S284 I285 V338 D340M111-H314 VanDerWaalsContact SD-CE1 3.59Å; F147-H314 AromaticContact CD1-CE1 3.69Å; F147-H314 AromaticContact CE1-CE1 3.37Å; F147-H314 WeakPolarHBondContact CE1-CE1 3.5Å; F147-H314 AromaticContact CE1-ND1 3.45Å; F147-H314 WeakPolarHBondContact CE1-ND1 3.31Å; R220-H314 PolarHBondContact NH2-CE1 3.32Å; R220-H314 PolarHBondContact NH2-ND1 3.03Å; R220-H314 PolarHBondContact NH2-NE2 3.25Å; R220-H314 VanDerWaalsContact NH2-NE2 3.12Å; E246-H314 IonicContact OE1-CG 2.84Å; E246-H314 IonicContact OE1-ND1 3.59Å; E246-H314 PolarHBondContact OE1-ND1 2.72Å; E246-H314 IonicContact OE2-ND1 3.89Å; I282-H314 HydrophobicContact CG2-CB 3.91Å; L283-H314 PolarHBondContact O-N 3.31Å; S284-H314 CarbonylContact C-O 3.36Å; S284-H314 WeakPolarHBondContact CA-O 3.2Å; I285-H314 PolarHBondContact N-O 3.48Å; H314-V338 WeakPolarHBondContact CA-O 3.46Å; H314-V338 HydrophobicContact CB-CB 4.27Å; H314-V338 PolarHBondContact CD2-O 2.68Å; H314-V338 VanDerWaalsContact NE2-CG1 3.33Å; H314-V338 WeakPolarHBondContact NE2-CG1 3.42Å; H314-D340 IonicContact CD2-OD1 2.79Å; H314-D340 PolarHBondContact CD2-OD1 3.14Å; H314-D340 IonicContact CE1-OD1 3.92Å; H314-D340 PolarHBondContact CE1-OD1 3.37Å; H314-D340 IonicContact NE2-OD1 2.87Å; H314-D340 PolarHBondContact NE2-OD1 3.32Å
315V98.9Very high97.7Very high0 Ų034.6 Ų34.60%020%0.198CC..EExtended strand (participates in β ladder)trans-115.2126.2176.7-167.40000111.5I285 L292 I301 I313 M328 C331 A336 V338 V339 D340I285-V315 HydrophobicContact CB-CG1 4.43Å; L292-V315 HydrophobicContact CD1-CG1 4.19Å; I301-V315 HydrophobicContact CD1-CG2 3.51Å; I301-V315 HydrophobicContact CG1-CG2 4.07Å; I313-V315 HydrophobicContact CG2-CG2 4.2Å; V315-M328 HydrophobicContact CB-CE 4.37Å; V315-M328 HydrophobicContact CB-SD 4.28Å; V315-M328 HydrophobicContact CG1-CE 3.64Å; V315-M328 HydrophobicContact CG1-SD 4.1Å; V315-C331 HydrophobicContact CB-CB 4.35Å; V315-C331 HydrophobicContact CG2-CB 4.03Å; V315-A336 HydrophobicContact CG2-CB 3.81Å; V315-V338 PolarHBondContact N-O 3.04Å; V315-V339 HydrophobicContact CB-CG1 4.49Å; V315-V339 WeakPolarHBondContact O-CA 3.32Å; V315-D340 PolarHBondContact O-N 3.33Å
316H98.8Very high97.7Very high0 Ų035.7 Ų35.70%021%0.213CC..EExtended strand (participates in β ladder)trans-110.2132.8172.916795.2000109.5D117 I285 K286 D287 H318 D340 Q352D117-H316 IonicContact OD2-CE1 2.7Å; D117-H316 PolarHBondContact OD2-CE1 3.34Å; D117-H316 IonicContact OD2-NE2 2.93Å; I285-H316 PolarHBondContact O-N 3.46Å; K286-H316 PolarHBondContact NZ-CD2 3.44Å; K286-H316 PolarHBondContact NZ-CE1 2.84Å; K286-H316 PolarHBondContact NZ-NE2 3.35Å; D287-H316 WeakPolarHBondContact CB-O 3.44Å; D287-H316 PolarHBondContact N-O 3.11Å; H316-H318 AromaticContact CE1-NE2 3.8Å; H316-H318 AromaticContact NE2-CD2 3.49Å; H316-H318 PolarHBondContact NE2-CD2 3.27Å; H316-H318 AromaticContact NE2-NE2 3.25Å; H316-H318 PolarHBondContact NE2-NE2 2.89Å; H316-D340 HydrophobicContact CB-CB 4.36Å; H316-D340 VanDerWaalsContact CB-OD2 3.29Å; H316-D340 WeakPolarHBondContact CB-OD2 3.45Å; H316-D340 IonicContact CE1-OD2 2.74Å; H316-D340 IonicContact CG-OD2 3.09Å; H316-D340 VanDerWaalsContact CG-OD2 3.32Å; H316-D340 IonicContact ND1-OD2 3.86Å; H316-D340 PolarHBondContact ND1-OD2 3.02Å; H316-Q352 PolarHBondContact CE1-NE2 2.68Å; H316-Q352 VanDerWaalsContact CE1-NE2 3.27Å
317T98.4Very high97.7Very high1 Ų128.9 Ų28.91%0.00618%0.177CC..EExtended strand (participates in β ladder)trans-141.3171.2169.7-165.40000111.5D287 M328 Q352 P353D287-T317 WeakPolarHBondContact O-CA 3.45Å; D287-T317 PolarHBondContact OD2-OG1 3.49Å; T317-M328 HydrophobicContact CG2-CE 3.39Å; T317-M328 HydrophobicContact CG2-CG 3.84Å; T317-M328 HydrophobicContact CG2-SD 3.68Å; T317-Q352 PolarHBondContact O-NE2 3.33Å; T317-P353 HydrophobicContact CG2-CG 3.62Å
318H97.7Very high97.7Very high6 Ų622.2 Ų22.23%0.02815%0.151CC..  trans-112.2151.7165.8-69-105.5000109.9D117 S121 D287 M288 G290 H316 T320 T350 S351 Q352D117-H318 IonicContact OD2-CE1 3.27Å; D117-H318 PolarHBondContact OD2-CE1 3.36Å; D117-H318 IonicContact OD2-NE2 3.58Å; D117-H318 PolarHBondContact OD2-NE2 3.11Å; S121-H318 PolarHBondContact OG-CE1 2.83Å; D287-H318 PolarHBondContact O-CD2 3.48Å; D287-H318 PolarHBondContact O-N 2.91Å; M288-H318 PolarHBondContact O-CD2 3.2Å; M288-H318 PolarHBondContact O-NE2 3.28Å; G290-H318 WeakPolarHBondContact CA-O 3.35Å; H316-H318 AromaticContact CE1-NE2 3.8Å; H316-H318 AromaticContact NE2-CD2 3.49Å; H316-H318 PolarHBondContact NE2-CD2 3.27Å; H316-H318 AromaticContact NE2-NE2 3.25Å; H316-H318 PolarHBondContact NE2-NE2 2.89Å; H318-T320 PolarHBondContact O-N 3.11Å; H318-T350 PolarHBondContact ND1-O 2.76Å; H318-S351 CarbonylContact C-O 3.54Å; H318-S351 WeakPolarHBondContact CA-O 3.35Å; H318-Q352 PolarHBondContact CE1-NE2 2.81Å; H318-Q352 VanDerWaalsContact CE1-NE2 3.34Å
319D96.9Very high97.7Very high22 Ų2223.4 Ų23.412%0.11816%0.158CC..  trans-93.328.9-179.4-163.130.4000112.3A321 G322 A323 G324 M349 S351 P353D319-A321 VanDerWaalsContact C-N 3.26Å; D319-A321 PolarHBondContact O-N 3.46Å; D319-G322 PolarHBondContact O-N 3.27Å; D319-G322 VanDerWaalsContact OD1-CA 3.29Å; D319-G322 WeakPolarHBondContact OD1-CA 3.24Å; D319-A323 PolarHBondContact OD1-N 3.2Å; D319-G324 WeakPolarHBondContact OD1-CA 3.42Å; D319-G324 PolarHBondContact OD1-N 3.43Å; D319-M349 CarbonylContact C-O 3.6Å; D319-M349 VanDerWaalsContact O-O 3.1Å; D319-S351 PolarHBondContact N-O 3.4Å; D319-P353 HydrophobicContact CB-CG 4.49Å
320T94.4Very high97.8Very high2 Ų220.5 Ų20.51%0.01214%0.14CC..THydrogen-bonded Turntrans-57.6-41.2-171-52.10000111.4A289 H318 M349 T350 G402 N403 V406A289-T320 PolarHBondContact O-OG1 3.33Å; H318-T320 PolarHBondContact O-N 3.11Å; T320-M349 WeakPolarHBondContact CA-O 3.19Å; T320-M349 PolarHBondContact N-O 2.69Å; T320-T350 HydrophobicContact CG2-CG2 4.24Å; T320-G402 CarbonylContact O-C 3.55Å; T320-G402 VanDerWaalsContact O-C 3.3Å; T320-G402 WeakPolarHBondContact O-CA 3.15Å; T320-N403 PolarHBondContact O-N 3.49Å; T320-V406 HydrophobicContact CG2-CB 3.95Å; T320-V406 HydrophobicContact CG2-CG1 4.13Å; T320-V406 HydrophobicContact CG2-CG2 4.05Å
321A94.2Very high97.8Very high24 Ų2414 Ų1420%0.19811%0.105CC..THydrogen-bonded Turntrans-85.5-2.6177.700000114.1D319 A323 V406 Y407D319-A321 VanDerWaalsContact C-N 3.26Å; D319-A321 PolarHBondContact O-N 3.46Å; A321-A323 VanDerWaalsContact C-N 3.3Å; A321-V406 HydrophobicContact CB-CG1 3.91Å; A321-Y407 HydrophobicContact CB-CD2 4.39Å; A321-Y407 HydrophobicContact CB-CE1 4.46Å; A321-Y407 HydrophobicContact CB-CE2 3.5Å; A321-Y407 WeakPolarHBondContact CB-OH 3.41Å
322G95.1Very high97.8Very high57 Ų5713 Ų1359%0.58810%0.099SC*.SBendtrans72.319.6-172.200000114.3D319D319-G322 PolarHBondContact O-N 3.27Å; D319-G322 VanDerWaalsContact OD1-CA 3.29Å; D319-G322 WeakPolarHBondContact OD1-CA 3.24Å
323A96.3Very high97.8Very high24 Ų2417.8 Ų17.820%0.19812%0.121CC..  trans-112.9-0.4-178.800000113.3D319 A321 V325 A326 A327D319-A323 PolarHBondContact OD1-N 3.2Å; A321-A323 VanDerWaalsContact C-N 3.3Å; A323-V325 PolarHBondContact O-N 3.25Å; A323-A326 PolarHBondContact O-N 3.48Å; A323-A327 PolarHBondContact O-N 3.24Å
324G97.6Very high97.8Very high3 Ų318.8 Ų18.83%0.03113%0.129CC..Hα-helixtrans-65.9-39.8-171.300000112.9D319 A326 A327 M328 P353D319-G324 WeakPolarHBondContact OD1-CA 3.42Å; D319-G324 PolarHBondContact OD1-N 3.43Å; G324-A326 VanDerWaalsContact C-N 3.34Å; G324-A326 PolarHBondContact O-N 2.72Å; G324-A327 PolarHBondContact O-N 2.93Å; G324-M328 WeakPolarHBondContact O-CG 3.41Å; G324-M328 PolarHBondContact O-N 2.79Å; G324-P353 VanDerWaalsContact C-CG 3.48Å
325V98.4Very high97.8Very high32 Ų3219.9 Ų19.919%0.19414%0.14CC..Hα-helixtrans-58.8-47.1174.3175.50000110.6A323 A327 M328 L329 P353 A357 I358A323-V325 PolarHBondContact O-N 3.25Å; V325-A327 VanDerWaalsContact C-N 3.34Å; V325-A327 PolarHBondContact O-N 3.46Å; V325-M328 PolarHBondContact O-N 2.96Å; V325-L329 HydrophobicContact CG1-CD1 4.23Å; V325-L329 WeakPolarHBondContact O-CG 3.4Å; V325-L329 PolarHBondContact O-N 3.28Å; V325-P353 HydrophobicContact CG2-CB 3.83Å; V325-A357 HydrophobicContact CG1-CB 4.13Å; V325-A357 HydrophobicContact CG2-CB 4.06Å; V325-I358 HydrophobicContact CB-CD1 4.47Å; V325-I358 HydrophobicContact CG1-CD1 3.87Å
326A98.5Very high97.7Very high50 Ų5020.2 Ų20.241%0.41314%0.144SC..Hα-helixtrans-65-38.3178.600000112.1P294 A323 G324 A330P294-A326 HydrophobicContact CG-CB 4.01Å; A323-A326 PolarHBondContact O-N 3.48Å; G324-A326 VanDerWaalsContact C-N 3.34Å; G324-A326 PolarHBondContact O-N 2.72Å; A326-A330 WeakPolarHBondContact O-CB 3.45Å; A326-A330 PolarHBondContact O-N 3.1Å
327A98.5Very high97.7Very high0 Ų020.9 Ų20.90%015%0.147CC..Hα-helixtrans-65.5-42.5176.100000112.3L292 A323 G324 V325 A330 C331L292-A327 WeakPolarHBondContact O-CB 3.25Å; A323-A327 PolarHBondContact O-N 3.24Å; G324-A327 PolarHBondContact O-N 2.93Å; V325-A327 VanDerWaalsContact C-N 3.34Å; V325-A327 PolarHBondContact O-N 3.46Å; A327-A330 WeakPolarHBondContact O-CB 3.43Å; A327-A330 PolarHBondContact O-N 2.98Å; A327-C331 PolarHBondContact O-N 3.27Å; A327-C331 PolarHBondContact O-SG 3.04Å
328M98.8Very high97.8Very high0 Ų020.8 Ų20.80%015%0.147CC..Hα-helixtrans-68.1-38.9177.7-66.9-5486.600112.4V315 T317 G324 V325 A330 C331 A332 V339 P353 I358V315-M328 HydrophobicContact CB-CE 4.37Å; V315-M328 HydrophobicContact CB-SD 4.28Å; V315-M328 HydrophobicContact CG1-CE 3.64Å; V315-M328 HydrophobicContact CG1-SD 4.1Å; T317-M328 HydrophobicContact CG2-CE 3.39Å; T317-M328 HydrophobicContact CG2-CG 3.84Å; T317-M328 HydrophobicContact CG2-SD 3.68Å; G324-M328 WeakPolarHBondContact O-CG 3.41Å; G324-M328 PolarHBondContact O-N 2.79Å; V325-M328 PolarHBondContact O-N 2.96Å; M328-A330 VanDerWaalsContact C-N 3.31Å; M328-A330 PolarHBondContact O-N 3.16Å; M328-C331 WeakPolarHBondContact O-CB 3.21Å; M328-C331 PolarHBondContact O-N 3.43Å; M328-A332 PolarHBondContact O-N 3.36Å; M328-V339 HydrophobicContact CB-CB 4.2Å; M328-V339 HydrophobicContact CB-CG1 4.06Å; M328-V339 HydrophobicContact CB-CG2 4.37Å; M328-V339 HydrophobicContact CG-CB 4.18Å; M328-V339 HydrophobicContact CG-CG1 4.33Å; M328-V339 HydrophobicContact SD-CB 3.81Å; M328-V339 HydrophobicContact SD-CG1 3.78Å; M328-P353 HydrophobicContact CG-CB 4.48Å; M328-P353 HydrophobicContact CG-CG 3.83Å; M328-I358 HydrophobicContact CB-CD1 3.92Å
329L98.8Very high97.8Very high42 Ų4220.5 Ų20.522%0.2215%0.145CC..Hα-helixtrans-60.9-41.8171-68.4172.9000111.4V325 C331 A332 E333 I358 C361 T362V325-L329 HydrophobicContact CG1-CD1 4.23Å; V325-L329 WeakPolarHBondContact O-CG 3.4Å; V325-L329 PolarHBondContact O-N 3.28Å; L329-C331 PolarHBondContact O-N 2.88Å; L329-A332 PolarHBondContact O-N 2.88Å; L329-E333 WeakPolarHBondContact O-CB 3.38Å; L329-E333 WeakPolarHBondContact O-CG 3.26Å; L329-E333 PolarHBondContact O-N 3.32Å; L329-I358 HydrophobicContact CD2-CD1 4.16Å; L329-I358 HydrophobicContact CG-CD1 4.06Å; L329-C361 HydrophobicContact CD1-CB 3.92Å; L329-C361 HydrophobicContact CD2-CB 4.02Å; L329-T362 HydrophobicContact CD2-CG2 3.79Å
330A98.8Very high97.9Very high5 Ų519.5 Ų19.54%0.04114%0.14CC..Hα-helixtrans-65.5-35.6175.600000112.9P294 K298 A326 A327 M328 E333 A334P294-A330 HydrophobicContact CB-CB 3.95Å; K298-A330 HydrophobicContact CG-CB 4.15Å; A326-A330 WeakPolarHBondContact O-CB 3.45Å; A326-A330 PolarHBondContact O-N 3.1Å; A327-A330 WeakPolarHBondContact O-CB 3.43Å; A327-A330 PolarHBondContact O-N 2.98Å; M328-A330 VanDerWaalsContact C-N 3.31Å; M328-A330 PolarHBondContact O-N 3.16Å; A330-E333 PolarHBondContact O-N 3.28Å; A330-A334 WeakPolarHBondContact O-CB 3.34Å; A330-A334 PolarHBondContact O-N 2.97Å
331C98.8Very high98.1Very high0 Ų019.4 Ų19.40%014%0.139CC..Hα-helixtrans-65.1-45.7172.7-68.50000111.6S297 I301 V315 A327 M328 L329 E333 A334 G335 A336S297-C331 VanDerWaalsContact CB-SG 3.52Å; I301-C331 HydrophobicContact CG1-CB 4.17Å; V315-C331 HydrophobicContact CB-CB 4.35Å; V315-C331 HydrophobicContact CG2-CB 4.03Å; A327-C331 PolarHBondContact O-N 3.27Å; A327-C331 PolarHBondContact O-SG 3.04Å; M328-C331 WeakPolarHBondContact O-CB 3.21Å; M328-C331 PolarHBondContact O-N 3.43Å; L329-C331 PolarHBondContact O-N 2.88Å; C331-E333 VanDerWaalsContact C-N 3.31Å; C331-E333 PolarHBondContact O-N 3.5Å; C331-A334 CarbonylContact O-C 3.41Å; C331-A334 PolarHBondContact O-N 3.49Å; C331-A334 VanDerWaalsContact O-N 3.14Å; C331-G335 PolarHBondContact O-N 3.31Å; C331-G335 VanDerWaalsContact O-N 3.12Å; C331-A336 HydrophobicContact CB-CB 4.01Å; C331-A336 WeakPolarHBondContact O-CB 3.35Å; C331-A336 PolarHBondContact O-N 3.49Å
332A98.6Very high98.4Very high1 Ų118.2 Ų18.21%0.00813%0.13CC..Hα-helixtrans-59.7-43.6174.900000110.9L108 M328 L329 A334 G335 Y367L108-A332 HydrophobicContact CD1-CB 3.94Å; L108-A332 HydrophobicContact CD2-CB 3.82Å; L108-A332 HydrophobicContact CG-CB 4.41Å; M328-A332 PolarHBondContact O-N 3.36Å; L329-A332 PolarHBondContact O-N 2.88Å; A332-A334 PolarHBondContact O-N 2.85Å; A332-G335 PolarHBondContact O-N 3.33Å; A332-G335 VanDerWaalsContact O-N 3.09Å; A332-Y367 HydrophobicContact CB-CD1 4.44Å; A332-Y367 VanDerWaalsContact O-CE1 3.26Å; A332-Y367 WeakPolarHBondContact O-CE1 3.48Å
333E98.5Very high98.5Very high105 Ų10515.5 Ų15.549%0.49110%0.102SC..Hα-helixtrans-58.2-35.4174.6-78.5178.5-175.600113.8K298 L329 A330 C331 G335 Y367K298-E333 WeakPolarHBondContact CE-OE2 3.47Å; K298-E333 IonicContact NZ-OE2 2.64Å; K298-E333 PolarHBondContact NZ-OE2 2.86Å; L329-E333 WeakPolarHBondContact O-CB 3.38Å; L329-E333 WeakPolarHBondContact O-CG 3.26Å; L329-E333 PolarHBondContact O-N 3.32Å; A330-E333 PolarHBondContact O-N 3.28Å; C331-E333 VanDerWaalsContact C-N 3.31Å; C331-E333 PolarHBondContact O-N 3.5Å; E333-G335 VanDerWaalsContact C-N 3.33Å; E333-Y367 WeakPolarHBondContact CA-OH 3.25Å; E333-Y367 HydrophobicContact CG-CE2 3.97Å; E333-Y367 PolarHBondContact O-OH 3.4Å
334A98.6Very high98.6Very high20 Ų2016.7 Ų16.717%0.16511%0.105CC..THydrogen-bonded Turntrans-85.8-1.7179.800000113.9I301 A330 C331 A332I301-A334 HydrophobicContact CB-CB 3.87Å; I301-A334 HydrophobicContact CG2-CB 3.91Å; A330-A334 WeakPolarHBondContact O-CB 3.34Å; A330-A334 PolarHBondContact O-N 2.97Å; C331-A334 CarbonylContact O-C 3.41Å; C331-A334 PolarHBondContact O-N 3.49Å; C331-A334 VanDerWaalsContact O-N 3.14Å; A332-A334 PolarHBondContact O-N 2.85Å
335G98.1Very high98.6Very high23 Ų2316.9 Ų16.924%0.23711%0.105CC..THydrogen-bonded Turntrans101.323.4173.400000115.7R305 C331 A332 E333R305-G335 PolarHBondContact NE-O 2.93Å; R305-G335 VanDerWaalsContact NE-O 3.07Å; R305-G335 PolarHBondContact NH2-O 3.02Å; C331-G335 PolarHBondContact O-N 3.31Å; C331-G335 VanDerWaalsContact O-N 3.12Å; A332-G335 PolarHBondContact O-N 3.33Å; A332-G335 VanDerWaalsContact O-N 3.09Å; E333-G335 VanDerWaalsContact C-N 3.33Å
336A98.8Very high98.6Very high8 Ų815.3 Ų15.37%0.06610%0.096CC..  trans-64.5138.3162.100000110.4I301 I313 V315 C331I301-A336 HydrophobicContact CG2-CB 4.09Å; I313-A336 HydrophobicContact CG2-CB 4.44Å; V315-A336 HydrophobicContact CG2-CB 3.81Å; C331-A336 HydrophobicContact CB-CB 4.01Å; C331-A336 WeakPolarHBondContact O-CB 3.35Å; C331-A336 PolarHBondContact O-N 3.49Å
337D98.9Very high98.6Very high13 Ų1313.5 Ų13.57%0.078%0.081CC..SBendtrans-90.5-29178-48.9-82.8000111.4V102 R103 L109 R305 P312 I313V102-D337 HydrophobicContact CG1-CB 4.31Å; R103-D337 IonicContact CZ-OD1 3.17Å; R103-D337 IonicContact NE-OD1 3.83Å; R103-D337 IonicContact NH1-OD1 2.91Å; R103-D337 PolarHBondContact NH1-OD1 3.07Å; L109-D337 PolarHBondContact N-O 2.8Å; R305-D337 IonicContact CZ-OD2 3.81Å; R305-D337 VanDerWaalsContact NH2-CG 3.31Å; R305-D337 IonicContact NH2-OD1 2.69Å; R305-D337 PolarHBondContact NH2-OD1 2.92Å; R305-D337 IonicContact NH2-OD2 3.66Å; R305-D337 PolarHBondContact NH2-OD2 3.24Å; P312-D337 WeakPolarHBondContact CA-OD2 3.44Å; I313-D337 PolarHBondContact N-OD2 2.73Å; I313-D337 PolarHBondContact O-N 3.03Å
338V98.9Very high98.4Very high0 Ų014.1 Ų14.10%09%0.087CC..EExtended strand (participates in β ladder)trans-135.1139.8-177.8-165.10000111.1V102 L109 M111 F147 I313 H314 V315V102-V338 HydrophobicContact CG1-CG2 3.94Å; L109-V338 HydrophobicContact CB-CG1 4.33Å; L109-V338 HydrophobicContact CB-CG2 4.1Å; L109-V338 HydrophobicContact CD1-CG2 4.46Å; L109-V338 WeakPolarHBondContact O-CA 3.31Å; M111-V338 HydrophobicContact CB-CG1 4.29Å; F147-V338 HydrophobicContact CB-CG1 3.74Å; F147-V338 HydrophobicContact CB-CG2 4.22Å; F147-V338 HydrophobicContact CD1-CG1 3.67Å; F147-V338 HydrophobicContact CD1-CG2 4.29Å; F147-V338 HydrophobicContact CD2-CG1 4.48Å; F147-V338 HydrophobicContact CD2-CG2 3.74Å; F147-V338 HydrophobicContact CE1-CG1 4.38Å; F147-V338 HydrophobicContact CE2-CG2 4.14Å; F147-V338 HydrophobicContact CG-CB 4.43Å; F147-V338 HydrophobicContact CG-CG1 3.71Å; F147-V338 HydrophobicContact CG-CG2 3.82Å; I313-V338 PolarHBondContact O-N 3.02Å; H314-V338 WeakPolarHBondContact CA-O 3.46Å; H314-V338 HydrophobicContact CB-CB 4.27Å; H314-V338 PolarHBondContact CD2-O 2.68Å; H314-V338 VanDerWaalsContact NE2-CG1 3.33Å; H314-V338 WeakPolarHBondContact NE2-CG1 3.42Å; V315-V338 PolarHBondContact N-O 3.04Å
339V98.9Very high98.1Very high0 Ų015.4 Ų15.40%09%0.094CC..EExtended strand (participates in β ladder)trans-126.2147.6167.4-62.90000112.2L108 L109 L110 M111 V315 M328 V341L108-V339 HydrophobicContact CD1-CG1 4.2Å; L108-V339 HydrophobicContact CD1-CG2 4.24Å; L108-V339 HydrophobicContact CD2-CG2 3.74Å; L108-V339 HydrophobicContact CG-CG2 4.14Å; L109-V339 PolarHBondContact O-N 3.13Å; L109-V339 VanDerWaalsContact O-N 3.14Å; L110-V339 HydrophobicContact CD2-CG2 3.65Å; M111-V339 PolarHBondContact N-O 2.8Å; V315-V339 HydrophobicContact CB-CG1 4.49Å; V315-V339 WeakPolarHBondContact O-CA 3.32Å; M328-V339 HydrophobicContact CB-CB 4.2Å; M328-V339 HydrophobicContact CB-CG1 4.06Å; M328-V339 HydrophobicContact CB-CG2 4.37Å; M328-V339 HydrophobicContact CG-CB 4.18Å; M328-V339 HydrophobicContact CG-CG1 4.33Å; M328-V339 HydrophobicContact SD-CB 3.81Å; M328-V339 HydrophobicContact SD-CG1 3.78Å; V339-V341 HydrophobicContact CG2-CG1 4.48Å
340D98.9Very high97.9Very high0 Ų013.4 Ų13.40%08%0.083CC..EExtended strand (participates in β ladder)trans-80.4135.4174.3-72.49.2000111.5M111 T113 R220 H314 V315 H316 Q352M111-D340 HydrophobicContact CE-CB 4.19Å; M111-D340 WeakPolarHBondContact CE-OD1 3.39Å; M111-D340 WeakPolarHBondContact CE-OD2 3.33Å; T113-D340 HydrophobicContact CG2-CB 4.06Å; R220-D340 IonicContact CZ-OD1 2.9Å; R220-D340 IonicContact CZ-OD2 3.86Å; R220-D340 IonicContact NH1-OD1 2.7Å; R220-D340 IonicContact NH1-OD2 3.21Å; R220-D340 PolarHBondContact NH1-OD2 2.82Å; R220-D340 IonicContact NH2-OD1 3.02Å; R220-D340 PolarHBondContact NH2-OD1 3.26Å; R220-D340 VanDerWaalsContact NH2-OD1 3.09Å; R220-D340 IonicContact NH2-OD2 3.2Å; R220-D340 PolarHBondContact NH2-OD2 2.85Å; H314-D340 IonicContact CD2-OD1 2.79Å; H314-D340 PolarHBondContact CD2-OD1 3.14Å; H314-D340 IonicContact CE1-OD1 3.92Å; H314-D340 PolarHBondContact CE1-OD1 3.37Å; H314-D340 IonicContact NE2-OD1 2.87Å; H314-D340 PolarHBondContact NE2-OD1 3.32Å; V315-D340 PolarHBondContact O-N 3.33Å; H316-D340 HydrophobicContact CB-CB 4.36Å; H316-D340 VanDerWaalsContact CB-OD2 3.29Å; H316-D340 WeakPolarHBondContact CB-OD2 3.45Å; H316-D340 IonicContact CE1-OD2 2.74Å; H316-D340 IonicContact CG-OD2 3.09Å; H316-D340 VanDerWaalsContact CG-OD2 3.32Å; H316-D340 IonicContact ND1-OD2 3.86Å; H316-D340 PolarHBondContact ND1-OD2 3.02Å; D340-Q352 HydrophobicContact CB-CG 4.07Å
341V98.9Very high97.8Very high0 Ų013.1 Ų13.10%08%0.081CC..EExtended strand (participates in β ladder)trans-137.7159.2176.2-64.60000110.6L110 M111 D112 T113 V339 P353 M355 I358L110-V341 HydrophobicContact CB-CG2 3.97Å; L110-V341 HydrophobicContact CD1-CG2 4.02Å; L110-V341 HydrophobicContact CD2-CG1 4.21Å; L110-V341 HydrophobicContact CG-CG2 4.44Å; M111-V341 PolarHBondContact O-N 3.25Å; D112-V341 WeakPolarHBondContact CA-O 3.25Å; T113-V341 PolarHBondContact N-O 2.88Å; T113-V341 PolarHBondContact OG1-O 3.34Å; V339-V341 HydrophobicContact CG2-CG1 4.48Å; V341-P353 WeakPolarHBondContact CA-O 3.47Å; V341-M355 HydrophobicContact CB-CB 3.96Å; V341-M355 HydrophobicContact CG2-CB 3.84Å; V341-M355 HydrophobicContact CG2-CE 3.75Å; V341-M355 HydrophobicContact CG2-CG 3.93Å; V341-I358 HydrophobicContact CG1-CB 4.31Å; V341-I358 HydrophobicContact CG1-CG1 4Å
342A98.8Very high97.7Very high0 Ų013.1 Ų13.10%08%0.081CC..BIsolated β-bridgetrans-119.3153.4164.200000109.7A118 M346 A347 Q352 P353 M355A118-A342 HydrophobicContact CB-CB 3.9Å; A342-M346 WeakPolarHBondContact CB-O 3.45Å; A342-A347 HydrophobicContact CB-CB 4.02Å; A342-Q352 HydrophobicContact CB-CB 3.99Å; A342-P353 PolarHBondContact N-O 2.82Å; A342-P353 VanDerWaalsContact N-O 3.07Å; A342-M355 VanDerWaalsContact O-CB 3.25Å; A342-M355 WeakPolarHBondContact O-CB 3.47Å; A342-M355 PolarHBondContact O-N 3.07Å
343V98.6Very high97.7Very high0 Ų013.1 Ų13.10%08%0.081CC..  trans-59.1146.8171.370.30000110.4T114 S345 M346 A347 Y379 S380 W383T114-V343 HydrophobicContact CG2-CG1 3.64Å; T114-V343 PolarHBondContact OG1-N 2.89Å; V343-S345 PolarHBondContact O-N 3.13Å; V343-S345 VanDerWaalsContact O-N 3.16Å; V343-M346 HydrophobicContact CG1-CB 3.85Å; V343-M346 HydrophobicContact CG1-CG 4.02Å; V343-M346 CarbonylContact O-C 3.58Å; V343-M346 VanDerWaalsContact O-C 3.25Å; V343-M346 WeakPolarHBondContact O-CA 3.41Å; V343-M346 PolarHBondContact O-N 3.42Å; V343-A347 WeakPolarHBondContact O-CB 3.24Å; V343-A347 PolarHBondContact O-N 3.42Å; V343-Y379 HydrophobicContact CB-CD1 3.61Å; V343-Y379 HydrophobicContact CB-CE1 3.64Å; V343-Y379 HydrophobicContact CB-CG 4.32Å; V343-Y379 HydrophobicContact CG1-CD1 4.39Å; V343-Y379 HydrophobicContact CG1-CE1 4.2Å; V343-Y379 HydrophobicContact CG2-CD1 3.36Å; V343-Y379 HydrophobicContact CG2-CE1 3.95Å; V343-Y379 HydrophobicContact CG2-CG 3.73Å; V343-S380 VanDerWaalsContact CG2-CA 3.5Å; V343-W383 HydrophobicContact CG1-CB 4.03Å; V343-W383 HydrophobicContact CG1-CG 3.86Å
344D98.3Very high97.7Very high49 Ų499.2 Ų9.226%0.2627%0.065SC..G310 helixtrans-53.4-44.6-163.6-58.8-17.5000114.5M346 A347 S354 G356D344-M346 PolarHBondContact O-N 3.21Å; D344-A347 PolarHBondContact O-N 3.33Å; D344-A347 VanDerWaalsContact O-N 3.14Å; D344-S354 WeakPolarHBondContact OD1-CB 3.46Å; D344-S354 PolarHBondContact OD1-OG 3.46Å; D344-G356 WeakPolarHBondContact OD1-CA 3.19Å; D344-G356 PolarHBondContact OD1-N 2.85Å
345S97.6Very high97.7Very high6 Ų68.2 Ų8.24%0.0426%0.057CC..G310 helixtrans-67.6-14.3177.752.60000114.4V343 S380 W383 E384 R387V343-S345 PolarHBondContact O-N 3.13Å; V343-S345 VanDerWaalsContact O-N 3.16Å; S345-S380 WeakPolarHBondContact CB-O 3.19Å; S345-S380 PolarHBondContact N-OG 3.44Å; S345-S380 PolarHBondContact OG-O 3.02Å; S345-S380 PolarHBondContact OG-OG 2.83Å; S345-W383 WeakPolarHBondContact OG-CB 3.43Å; S345-E384 WeakPolarHBondContact CB-OE2 3.18Å; S345-E384 PolarHBondContact OG-N 3.24Å; S345-R387 WeakPolarHBondContact O-CD 3.5Å; S345-R387 PolarHBondContact O-NH1 2.83Å
346M98.1Very high97.8Very high0 Ų07.4 Ų7.40%05%0.049CC..G310 helixtrans-116.212.1175.9-63.7-67.4-71.700112.5T114 A118 H119 L122 L123 A342 V343 D344 S351 W383 R387T114-M346 HydrophobicContact CG2-CB 4.13Å; T114-M346 HydrophobicContact CG2-CG 4.08Å; A118-M346 HydrophobicContact CB-CB 4.29Å; H119-M346 HydrophobicContact CB-CE 3.78Å; L122-M346 HydrophobicContact CD1-CB 4.48Å; L122-M346 WeakPolarHBondContact CD1-O 3.4Å; L123-M346 HydrophobicContact CD1-CE 3.73Å; L123-M346 HydrophobicContact CD1-SD 4.27Å; L123-M346 HydrophobicContact CG-CE 4.44Å; A342-M346 WeakPolarHBondContact CB-O 3.45Å; V343-M346 HydrophobicContact CG1-CB 3.85Å; V343-M346 HydrophobicContact CG1-CG 4.02Å; V343-M346 CarbonylContact O-C 3.58Å; V343-M346 VanDerWaalsContact O-C 3.25Å; V343-M346 WeakPolarHBondContact O-CA 3.41Å; V343-M346 PolarHBondContact O-N 3.42Å; D344-M346 PolarHBondContact O-N 3.21Å; M346-S351 VanDerWaalsContact O-CB 3.31Å; M346-S351 WeakPolarHBondContact O-CB 3.15Å; M346-S351 PolarHBondContact O-OG 3.25Å; M346-W383 HydrophobicContact CE-CE3 4.32Å; M346-W383 HydrophobicContact CE-CZ3 4.43Å; M346-W383 HydrophobicContact CG-CB 3.89Å; M346-W383 HydrophobicContact CG-CD2 4.03Å; M346-W383 HydrophobicContact CG-CE3 3.96Å; M346-W383 HydrophobicContact CG-CG 4.03Å; M346-W383 HydrophobicContact SD-CE3 4.11Å; M346-R387 HydrophobicContact SD-CB 4.11Å; M346-R387 HydrophobicContact SD-CG 4.19Å
347A97.7Very high97.8Very high11 Ų118.5 Ų8.59%0.0916%0.058CC..  trans-105.5177179.900000112.5A342 V343 D344 Q352A342-A347 HydrophobicContact CB-CB 4.02Å; V343-A347 WeakPolarHBondContact O-CB 3.24Å; V343-A347 PolarHBondContact O-N 3.42Å; D344-A347 PolarHBondContact O-N 3.33Å; D344-A347 VanDerWaalsContact O-N 3.14Å; A347-Q352 WeakPolarHBondContact CB-O 3.39Å
348G95.4Very high97.7Very high14 Ų147.9 Ų7.914%0.1446%0.055CC..SBendtrans74.3175.517600000113.4T350 S351 Q352G348-T350 PolarHBondContact O-N 3Å; G348-S351 WeakPolarHBondContact O-CB 3.33Å; G348-S351 PolarHBondContact O-N 3.48Å; G348-Q352 PolarHBondContact N-O 3.37Å
349M92.5Very high97.7Very high26 Ų268.1 Ų8.113%0.1286%0.056CC..THydrogen-bonded Turntrans52.3-134.4-174.5-53.9-178.4-69.700110L122 D319 T320 S351 T396 M399L122-M349 HydrophobicContact CD2-CE 3.68Å; D319-M349 CarbonylContact C-O 3.6Å; D319-M349 VanDerWaalsContact O-O 3.1Å; T320-M349 WeakPolarHBondContact CA-O 3.19Å; T320-M349 PolarHBondContact N-O 2.69Å; M349-S351 PolarHBondContact O-N 2.88Å; M349-S351 VanDerWaalsContact O-N 3.11Å; M349-T396 HydrophobicContact CE-CG2 3.54Å; M349-T396 HydrophobicContact SD-CG2 3.86Å; M349-M399 HydrophobicContact CB-CE 3.89Å; M349-M399 HydrophobicContact CG-CE 4.48Å; M349-M399 HydrophobicContact SD-CE 4.3Å
350T93.4Very high97.7Very high0 Ų010.5 Ų10.50%08%0.076CC..THydrogen-bonded Turntrans-70.1-2.2178.748.20000114S121 H318 T320 G348 M399 Y416S121-T350 WeakPolarHBondContact CB-O 3.38Å; S121-T350 PolarHBondContact O-OG1 3.49Å; S121-T350 PolarHBondContact OG-O 3.07Å; H318-T350 PolarHBondContact ND1-O 2.76Å; T320-T350 HydrophobicContact CG2-CG2 4.24Å; G348-T350 PolarHBondContact O-N 3Å; T350-M399 HydrophobicContact CG2-CE 3.88Å; T350-Y416 HydrophobicContact CG2-CD1 4.34Å; T350-Y416 HydrophobicContact CG2-CG 4.28Å
351S96.6Very high97.7Very high0 Ų014 Ų140%010%0.099CC..SBendtrans-85.7-174.2175.2-160.50000112A118 H318 D319 M346 G348 M349A118-S351 VanDerWaalsContact CA-OG 3.3Å; A118-S351 WeakPolarHBondContact CA-OG 3.3Å; A118-S351 WeakPolarHBondContact CB-OG 3.33Å; H318-S351 CarbonylContact C-O 3.54Å; H318-S351 WeakPolarHBondContact CA-O 3.35Å; D319-S351 PolarHBondContact N-O 3.4Å; M346-S351 VanDerWaalsContact O-CB 3.31Å; M346-S351 WeakPolarHBondContact O-CB 3.15Å; M346-S351 PolarHBondContact O-OG 3.25Å; G348-S351 WeakPolarHBondContact O-CB 3.33Å; G348-S351 PolarHBondContact O-N 3.48Å; M349-S351 PolarHBondContact O-N 2.88Å; M349-S351 VanDerWaalsContact O-N 3.11Å
352Q98.3Very high97.7Very high0 Ų014.1 Ų14.10%010%0.1CC..PPolyproline II helixtrans-69.4164.4172.4-82.162.659.800112.6T113 D117 H316 T317 H318 D340 A342 A347 G348T113-Q352 HydrophobicContact CG2-CG 3.86Å; T113-Q352 VanDerWaalsContact OG1-CD 3.32Å; T113-Q352 WeakPolarHBondContact OG1-CG 3.38Å; T113-Q352 PolarHBondContact OG1-OE1 3.11Å; D117-Q352 PolarHBondContact OD2-NE2 3.3Å; H316-Q352 PolarHBondContact CE1-NE2 2.68Å; H316-Q352 VanDerWaalsContact CE1-NE2 3.27Å; T317-Q352 PolarHBondContact O-NE2 3.33Å; H318-Q352 PolarHBondContact CE1-NE2 2.81Å; H318-Q352 VanDerWaalsContact CE1-NE2 3.34Å; D340-Q352 HydrophobicContact CB-CG 4.07Å; A342-Q352 HydrophobicContact CB-CB 3.99Å; A347-Q352 WeakPolarHBondContact CB-O 3.39Å; G348-Q352 PolarHBondContact N-O 3.37Å
353P98.4Very high97.6Very high0 Ų021.1 Ų21.10%013%0.13CC..PPolyproline II helixtrans-55.2150.1167.2-25.236.6000112.9T317 D319 G324 V325 M328 V341 A342 M355T317-P353 HydrophobicContact CG2-CG 3.62Å; D319-P353 HydrophobicContact CB-CG 4.49Å; G324-P353 VanDerWaalsContact C-CG 3.48Å; V325-P353 HydrophobicContact CG2-CB 3.83Å; M328-P353 HydrophobicContact CG-CB 4.48Å; M328-P353 HydrophobicContact CG-CG 3.83Å; V341-P353 WeakPolarHBondContact CA-O 3.47Å; A342-P353 PolarHBondContact N-O 2.82Å; A342-P353 VanDerWaalsContact N-O 3.07Å; P353-M355 PolarHBondContact O-N 3.45Å
354S98.6Very high97.6Very high23 Ų2324.6 Ų24.616%0.16117%0.167CC..BIsolated β-bridgetrans-65.3125.9179.9151.70000112D344 G356 A357 I358D344-S354 WeakPolarHBondContact OD1-CB 3.46Å; D344-S354 PolarHBondContact OD1-OG 3.46Å; S354-G356 PolarHBondContact OG-N 2.73Å; S354-A357 PolarHBondContact O-N 3.29Å; S354-A357 WeakPolarHBondContact OG-CB 3.38Å; S354-A357 PolarHBondContact OG-N 2.76Å; S354-I358 WeakPolarHBondContact O-CG1 3.35Å; S354-I358 PolarHBondContact O-N 2.87Å; S354-I358 VanDerWaalsContact O-N 3.13Å
355M98.8Very high97.5Very high0 Ų025.4 Ų25.40%017%0.173CC..Hα-helixtrans-58.3-48.4173.7179.9-174.6-6900110.9L110 D112 F143 V341 A342 P353 A357 I358 V359 V376 Y379L110-M355 HydrophobicContact CD1-CG 4.14Å; D112-M355 HydrophobicContact CB-CE 3.9Å; F143-M355 HydrophobicContact CD1-SD 4.31Å; F143-M355 HydrophobicContact CE1-SD 3.66Å; F143-M355 HydrophobicContact CZ-SD 4.42Å; V341-M355 HydrophobicContact CB-CB 3.96Å; V341-M355 HydrophobicContact CG2-CB 3.84Å; V341-M355 HydrophobicContact CG2-CE 3.75Å; V341-M355 HydrophobicContact CG2-CG 3.93Å; A342-M355 VanDerWaalsContact O-CB 3.25Å; A342-M355 WeakPolarHBondContact O-CB 3.47Å; A342-M355 PolarHBondContact O-N 3.07Å; P353-M355 PolarHBondContact O-N 3.45Å; M355-A357 VanDerWaalsContact C-N 3.3Å; M355-A357 PolarHBondContact O-N 3.38Å; M355-I358 PolarHBondContact O-N 3.36Å; M355-V359 HydrophobicContact CG-CG2 4.26Å; M355-V359 WeakPolarHBondContact O-CB 3.36Å; M355-V359 VanDerWaalsContact O-CG2 3.25Å; M355-V359 WeakPolarHBondContact O-CG2 3.38Å; M355-V359 PolarHBondContact O-N 2.93Å; M355-V376 HydrophobicContact CB-CG1 4.39Å; M355-V376 HydrophobicContact CG-CG1 4.19Å; M355-V376 HydrophobicContact CG-CG2 4.38Å; M355-V376 HydrophobicContact SD-CG1 4.15Å; M355-V376 HydrophobicContact SD-CG2 4.19Å; M355-Y379 HydrophobicContact CE-CE1 4.44Å
356G98.6Very high97.5Very high6 Ų632.7 Ų32.76%0.06220%0.204CC..Hα-helixtrans-60.6-39.4-179.900000112.4D344 S354 A360D344-G356 WeakPolarHBondContact OD1-CA 3.19Å; D344-G356 PolarHBondContact OD1-N 2.85Å; S354-G356 PolarHBondContact OG-N 2.73Å; G356-A360 WeakPolarHBondContact O-CB 3.44Å; G356-A360 PolarHBondContact O-N 3.35Å
357A98.6Very high97.6Very high31 Ų3135 Ų3526%0.25621%0.213SC..Hα-helixtrans-63.4-47.7175.500000112.1V325 S354 M355 A360 C361V325-A357 HydrophobicContact CG1-CB 4.13Å; V325-A357 HydrophobicContact CG2-CB 4.06Å; S354-A357 PolarHBondContact O-N 3.29Å; S354-A357 WeakPolarHBondContact OG-CB 3.38Å; S354-A357 PolarHBondContact OG-N 2.76Å; M355-A357 VanDerWaalsContact C-N 3.3Å; M355-A357 PolarHBondContact O-N 3.38Å; A357-A360 PolarHBondContact O-N 3.37Å; A357-C361 VanDerWaalsContact O-CB 3.3Å; A357-C361 WeakPolarHBondContact O-CB 3.48Å; A357-C361 PolarHBondContact O-N 3.07Å; A357-C361 PolarHBondContact O-SG 3.5Å
358I98.8Very high97.6Very high0 Ų037.2 Ų37.20%022%0.223CC..Hα-helixtrans-63.9-46178.4-65-68.2000111.2L108 L110 V325 M328 L329 V341 S354 M355 A360 C361 T362L108-I358 HydrophobicContact CD2-CG2 4.06Å; L110-I358 HydrophobicContact CD2-CG2 3.81Å; V325-I358 HydrophobicContact CB-CD1 4.47Å; V325-I358 HydrophobicContact CG1-CD1 3.87Å; M328-I358 HydrophobicContact CB-CD1 3.92Å; L329-I358 HydrophobicContact CD2-CD1 4.16Å; L329-I358 HydrophobicContact CG-CD1 4.06Å; V341-I358 HydrophobicContact CG1-CB 4.31Å; V341-I358 HydrophobicContact CG1-CG1 4Å; S354-I358 WeakPolarHBondContact O-CG1 3.35Å; S354-I358 PolarHBondContact O-N 2.87Å; S354-I358 VanDerWaalsContact O-N 3.13Å; M355-I358 PolarHBondContact O-N 3.36Å; I358-A360 VanDerWaalsContact C-N 3.34Å; I358-A360 PolarHBondContact O-N 2.93Å; I358-C361 PolarHBondContact O-N 3.2Å; I358-T362 HydrophobicContact CG2-CG2 4.38Å; I358-T362 WeakPolarHBondContact O-CB 3.33Å; I358-T362 WeakPolarHBondContact O-CG2 3.43Å; I358-T362 PolarHBondContact O-N 3.38Å; I358-T362 PolarHBondContact O-OG1 2.84Å
359V98.7Very high97.7Very high4 Ų436.8 Ų36.82%0.02422%0.218CC..Hα-helixtrans-59.1-45.4177172.10000110.7L110 M355 T362 K363 T369 I371 L373 V376L110-V359 HydrophobicContact CD1-CG2 3.81Å; M355-V359 HydrophobicContact CG-CG2 4.26Å; M355-V359 WeakPolarHBondContact O-CB 3.36Å; M355-V359 VanDerWaalsContact O-CG2 3.25Å; M355-V359 WeakPolarHBondContact O-CG2 3.38Å; M355-V359 PolarHBondContact O-N 2.93Å; V359-T362 PolarHBondContact O-OG1 3.47Å; V359-K363 PolarHBondContact O-N 2.89Å; V359-T369 HydrophobicContact CG2-CG2 4.5Å; V359-I371 HydrophobicContact CG1-CB 4.35Å; V359-I371 VanDerWaalsContact CG1-O 3.3Å; V359-I371 WeakPolarHBondContact CG1-O 3.49Å; V359-I371 HydrophobicContact CG2-CB 4.05Å; V359-I371 HydrophobicContact CG2-CD1 4.41Å; V359-I371 HydrophobicContact CG2-CG2 4.25Å; V359-L373 HydrophobicContact CB-CD1 4.14Å; V359-L373 HydrophobicContact CG1-CB 4.42Å; V359-L373 HydrophobicContact CG1-CD1 3.93Å; V359-V376 HydrophobicContact CG2-CG2 4.45Å
360A98.6Very high97.9Very high51 Ų5138.5 Ų38.542%0.42124%0.242SC..Hα-helixtrans-67.2-43.2179.700000112.8G356 A357 I358 T362 K363 L373G356-A360 WeakPolarHBondContact O-CB 3.44Å; G356-A360 PolarHBondContact O-N 3.35Å; A357-A360 PolarHBondContact O-N 3.37Å; I358-A360 VanDerWaalsContact C-N 3.34Å; I358-A360 PolarHBondContact O-N 2.93Å; A360-T362 VanDerWaalsContact C-N 3.33Å; A360-T362 PolarHBondContact O-N 3.46Å; A360-K363 PolarHBondContact O-N 3.05Å; A360-L373 HydrophobicContact CB-CD1 4.39Å; A360-L373 HydrophobicContact CB-CD2 4.23Å
361C98.5Very high98.1Very high73 Ų7339.1 Ų39.149%0.49325%0.245SC..Hα-helixtrans-70.1-28-178.5-73.90000113.5L329 A357 I358L329-C361 HydrophobicContact CD1-CB 3.92Å; L329-C361 HydrophobicContact CD2-CB 4.02Å; A357-C361 VanDerWaalsContact O-CB 3.3Å; A357-C361 WeakPolarHBondContact O-CB 3.48Å; A357-C361 PolarHBondContact O-N 3.07Å; A357-C361 PolarHBondContact O-SG 3.5Å; I358-C361 PolarHBondContact O-N 3.2Å
362T98.3Very high98.1Very high2 Ų241.8 Ų41.81%0.01227%0.267CS..Hα-helixtrans-90.7-14.918054.90000113.4L108 L329 I358 V359 A360 G364 T365 Y367 D368L108-T362 HydrophobicContact CD2-CG2 4.29Å; L329-T362 HydrophobicContact CD2-CG2 3.79Å; I358-T362 HydrophobicContact CG2-CG2 4.38Å; I358-T362 WeakPolarHBondContact O-CB 3.33Å; I358-T362 WeakPolarHBondContact O-CG2 3.43Å; I358-T362 PolarHBondContact O-N 3.38Å; I358-T362 PolarHBondContact O-OG1 2.84Å; V359-T362 PolarHBondContact O-OG1 3.47Å; A360-T362 VanDerWaalsContact C-N 3.33Å; A360-T362 PolarHBondContact O-N 3.46Å; T362-G364 PolarHBondContact O-N 2.79Å; T362-T365 WeakPolarHBondContact O-CB 3.35Å; T362-T365 WeakPolarHBondContact O-CG2 3.21Å; T362-T365 PolarHBondContact O-N 2.54Å; T362-T365 PolarHBondContact O-OG1 2.85Å; T362-Y367 WeakPolarHBondContact CB-O 3.25Å; T362-D368 WeakPolarHBondContact O-CA 3.48Å; T362-D368 PolarHBondContact O-N 3.08Å
363K98Very high98.1Very high147 Ų14743.9 Ų43.964%0.63928%0.278SS*.THydrogen-bonded Turntrans-55.9128.6-178-172.9174.4-177.91760112.5V359 A360 T365 D368V359-K363 PolarHBondContact O-N 2.89Å; A360-K363 PolarHBondContact O-N 3.05Å; K363-T365 PolarHBondContact O-N 3.44Å; K363-D368 WeakPolarHBondContact CA-OD2 3.39Å
364G96.9Very high98Very high74 Ų7450.2 Ų50.276%0.76331%0.308SS*.THydrogen-bonded Turntrans73.15.3-179.400000114.8T362 D368T362-G364 PolarHBondContact O-N 2.79Å; G364-D368 PolarHBondContact N-OD2 3.23Å
365T98.1Very high98Very high65 Ų6552 Ų5240%0.39931%0.313SS..SBendtrans-97.5175.2170.979.20000110.3T362 K363 Y367 D368T362-T365 WeakPolarHBondContact O-CB 3.35Å; T362-T365 WeakPolarHBondContact O-CG2 3.21Å; T362-T365 PolarHBondContact O-N 2.54Å; T362-T365 PolarHBondContact O-OG1 2.85Å; K363-T365 PolarHBondContact O-N 3.44Å; T365-Y367 PolarHBondContact O-N 2.68Å; T365-Y367 VanDerWaalsContact O-N 3.15Å; T365-Y367 PolarHBondContact OG1-N 3.28Å; T365-Y367 VanDerWaalsContact OG1-N 3.07Å; T365-D368 WeakPolarHBondContact O-CB 3.43Å; T365-D368 PolarHBondContact O-N 2.87Å
366K97.6Very high98Very high160 Ų16052 Ų5270%0.69631%0.313SS*.THydrogen-bonded Turntrans-66.4-8.6171.769178.4-172168.80114.1
367Y98.3Very high98Very high49 Ų4956.9 Ų56.919%0.19233%0.332CS..THydrogen-bonded Turntrans-10412178.1-55-61.4000112.6L108 A332 E333 T362 T365 T369L108-Y367 WeakPolarHBondContact CB-O 3.46Å; L108-Y367 PolarHBondContact N-O 3.07Å; A332-Y367 HydrophobicContact CB-CD1 4.44Å; A332-Y367 VanDerWaalsContact O-CE1 3.26Å; A332-Y367 WeakPolarHBondContact O-CE1 3.48Å; E333-Y367 WeakPolarHBondContact CA-OH 3.25Å; E333-Y367 HydrophobicContact CG-CE2 3.97Å; E333-Y367 PolarHBondContact O-OH 3.4Å; T362-Y367 WeakPolarHBondContact CB-O 3.25Å; T365-Y367 PolarHBondContact O-N 2.68Å; T365-Y367 VanDerWaalsContact O-N 3.15Å; T365-Y367 PolarHBondContact OG1-N 3.28Å; T365-Y367 VanDerWaalsContact OG1-N 3.07Å; Y367-T369 PolarHBondContact O-N 3.34Å
368D98.4Very high97.9Very high56 Ų5657.5 Ų57.530%0.29933%0.331SS..  trans-51.7129.3179-161.7-38.5000110.8G107 T362 K363 G364 T365 G370G107-D368 WeakPolarHBondContact CA-O 3.42Å; T362-D368 WeakPolarHBondContact O-CA 3.48Å; T362-D368 PolarHBondContact O-N 3.08Å; K363-D368 WeakPolarHBondContact CA-OD2 3.39Å; G364-D368 PolarHBondContact N-OD2 3.23Å; T365-D368 WeakPolarHBondContact O-CB 3.43Å; T365-D368 PolarHBondContact O-N 2.87Å; D368-G370 VanDerWaalsContact C-N 3.34Å; D368-G370 PolarHBondContact OD1-N 3.21Å
369T98.2Very high97.9Very high6 Ų657.5 Ų57.54%0.03733%0.331CS..  trans-80.6-17.9-176.863.20000112.5L108 L110 N145 V359 Y367 I371L108-T369 HydrophobicContact CB-CG2 4.41Å; L108-T369 WeakPolarHBondContact O-CA 3.19Å; L108-T369 WeakPolarHBondContact O-CG2 3.13Å; L110-T369 HydrophobicContact CD1-CG2 4.06Å; L110-T369 HydrophobicContact CD2-CG2 4.04Å; L110-T369 HydrophobicContact CG-CG2 3.97Å; N145-T369 PolarHBondContact ND2-O 2.92Å; V359-T369 HydrophobicContact CG2-CG2 4.5Å; Y367-T369 PolarHBondContact O-N 3.34Å; T369-I371 PolarHBondContact O-N 2.83Å; T369-I371 PolarHBondContact OG1-N 2.93Å
370G96.7Very high97.9Very high61 Ų6158.2 Ų58.263%0.62934%0.337SS*.  trans71.21.8-172.500000115D368D368-G370 VanDerWaalsContact C-N 3.34Å; D368-G370 PolarHBondContact OD1-N 3.21Å
371I97.6Very high97.9Very high13 Ų1362.1 Ų62.17%0.06735%0.346CS..  trans-79129.7177.4-62.9172.9000109.8L110 F143 N145 L146 V359 T369 L373 V376L110-I371 HydrophobicContact CB-CD1 4.45Å; L110-I371 HydrophobicContact CD1-CD1 3.69Å; L110-I371 HydrophobicContact CG-CD1 4.21Å; F143-I371 HydrophobicContact CD1-CD1 4.48Å; F143-I371 HydrophobicContact CD1-CG2 4.1Å; F143-I371 HydrophobicContact CE1-CG2 3.86Å; N145-I371 VanDerWaalsContact ND2-CG1 3.33Å; N145-I371 WeakPolarHBondContact ND2-CG1 3.21Å; L146-I371 HydrophobicContact CD2-CD1 4.24Å; V359-I371 HydrophobicContact CG1-CB 4.35Å; V359-I371 VanDerWaalsContact CG1-O 3.3Å; V359-I371 WeakPolarHBondContact CG1-O 3.49Å; V359-I371 HydrophobicContact CG2-CB 4.05Å; V359-I371 HydrophobicContact CG2-CD1 4.41Å; V359-I371 HydrophobicContact CG2-CG2 4.25Å; T369-I371 PolarHBondContact O-N 2.83Å; T369-I371 PolarHBondContact OG1-N 2.93Å; I371-L373 PolarHBondContact O-N 2.99Å; I371-V376 HydrophobicContact CG2-CG2 3.75Å
372A96.9Very high97.9Very high56 Ų5658.8 Ų58.846%0.46332%0.323SS..  trans-72.4118176.800000110.8E374 K375 V376A372-E374 PolarHBondContact O-N 2.83Å; A372-K375 HydrophobicContact CB-CG 4.06Å; A372-K375 WeakPolarHBondContact O-CB 3.25Å; A372-K375 PolarHBondContact O-N 3.32Å; A372-V376 PolarHBondContact O-N 3.39Å
373L97.3Very high97.9Very high44 Ų4458.7 Ų58.723%0.2332%0.323CS..Hα-helixtrans-59.5-33.2-176.2-166.866.7000113.4V359 A360 I371 K375 V376 F377V359-L373 HydrophobicContact CB-CD1 4.14Å; V359-L373 HydrophobicContact CG1-CB 4.42Å; V359-L373 HydrophobicContact CG1-CD1 3.93Å; A360-L373 HydrophobicContact CB-CD1 4.39Å; A360-L373 HydrophobicContact CB-CD2 4.23Å; I371-L373 PolarHBondContact O-N 2.99Å; L373-K375 VanDerWaalsContact C-N 3.26Å; L373-K375 PolarHBondContact O-N 2.82Å; L373-V376 HydrophobicContact CD1-CB 4.46Å; L373-V376 WeakPolarHBondContact O-CB 3.45Å; L373-V376 PolarHBondContact O-N 3.36Å; L373-V376 VanDerWaalsContact O-N 3.08Å; L373-F377 HydrophobicContact CB-CZ 4.5Å; L373-F377 HydrophobicContact CD1-CE1 4.03Å; L373-F377 HydrophobicContact CD1-CZ 4.27Å; L373-F377 HydrophobicContact CD2-CE1 4.11Å; L373-F377 HydrophobicContact CD2-CE2 4.29Å; L373-F377 HydrophobicContact CD2-CZ 3.53Å; L373-F377 HydrophobicContact CG-CE1 3.66Å; L373-F377 HydrophobicContact CG-CE2 4.08Å; L373-F377 HydrophobicContact CG-CZ 3.42Å; L373-F377 VanDerWaalsContact CG-CZ 3.42Å; L373-F377 WeakPolarHBondContact O-CD1 2.93Å; L373-F377 WeakPolarHBondContact O-CG 3.3Å; L373-F377 PolarHBondContact O-N 3.24Å; L373-F377 VanDerWaalsContact O-N 3.09Å
374E97.6Very high97.9Very high133 Ų13357.4 Ų57.462%0.62132%0.319SS*.Hα-helixtrans-58.2-37.5173.3-173.5179.9-17300112.2A372 V376 F377 D378A372-E374 PolarHBondContact O-N 2.83Å; E374-V376 VanDerWaalsContact C-N 3.32Å; E374-V376 PolarHBondContact O-N 3.23Å; E374-F377 WeakPolarHBondContact O-CB 3.18Å; E374-F377 PolarHBondContact O-N 3.48Å; E374-F377 VanDerWaalsContact O-N 3.16Å; E374-D378 PolarHBondContact O-N 3.28Å
375K97.8Very high97.9Very high60 Ų6056 Ų5626%0.26130%0.296SS..Hα-helixtrans-71.6-28.6176.5-59-53.6178.1-165.90112.9F138 N142 F143 A372 L373 F377 D378 Y379F138-K375 HydrophobicContact CE2-CD 4.46Å; F138-K375 HydrophobicContact CZ-CB 4.36Å; F138-K375 HydrophobicContact CZ-CD 4.04Å; N142-K375 HydrophobicContact CB-CB 4.13Å; N142-K375 HydrophobicContact CB-CD 4.39Å; N142-K375 HydrophobicContact CB-CG 4.11Å; N142-K375 WeakPolarHBondContact OD1-CD 2.97Å; N142-K375 WeakPolarHBondContact OD1-CE 3.35Å; F143-K375 HydrophobicContact CZ-CB 4.42Å; A372-K375 HydrophobicContact CB-CG 4.06Å; A372-K375 WeakPolarHBondContact O-CB 3.25Å; A372-K375 PolarHBondContact O-N 3.32Å; L373-K375 VanDerWaalsContact C-N 3.26Å; L373-K375 PolarHBondContact O-N 2.82Å; K375-F377 VanDerWaalsContact C-N 3.32Å; K375-D378 IonicContact NZ-OD2 2.95Å; K375-D378 PolarHBondContact NZ-OD2 2.88Å; K375-Y379 WeakPolarHBondContact O-CB 3.47Å; K375-Y379 PolarHBondContact O-N 3.07Å
376V98.4Very high97.9Very high0 Ų053 Ų530%028%0.277CS..Hα-helixtrans-65.9-38.6170-174.10000110.4F143 M355 V359 I371 A372 L373 E374 Y379 S380F143-V376 HydrophobicContact CE1-CG2 4.14Å; F143-V376 HydrophobicContact CZ-CG2 4.45Å; M355-V376 HydrophobicContact CB-CG1 4.39Å; M355-V376 HydrophobicContact CG-CG1 4.19Å; M355-V376 HydrophobicContact CG-CG2 4.38Å; M355-V376 HydrophobicContact SD-CG1 4.15Å; M355-V376 HydrophobicContact SD-CG2 4.19Å; V359-V376 HydrophobicContact CG2-CG2 4.45Å; I371-V376 HydrophobicContact CG2-CG2 3.75Å; A372-V376 PolarHBondContact O-N 3.39Å; L373-V376 HydrophobicContact CD1-CB 4.46Å; L373-V376 WeakPolarHBondContact O-CB 3.45Å; L373-V376 PolarHBondContact O-N 3.36Å; L373-V376 VanDerWaalsContact O-N 3.08Å; E374-V376 VanDerWaalsContact C-N 3.32Å; E374-V376 PolarHBondContact O-N 3.23Å; V376-Y379 PolarHBondContact O-N 2.9Å; V376-S380 VanDerWaalsContact O-CB 3.31Å; V376-S380 WeakPolarHBondContact O-CB 3.36Å; V376-S380 PolarHBondContact O-N 2.88Å
377F98.2Very high97.9Very high109 Ų10946.8 Ų46.848%0.47825%0.249SC..Hα-helixtrans-66.1-48.7177.4-55.3-26.3000112L373 E374 K375 Y379 S380 E381L373-F377 HydrophobicContact CB-CZ 4.5Å; L373-F377 HydrophobicContact CD1-CE1 4.03Å; L373-F377 HydrophobicContact CD1-CZ 4.27Å; L373-F377 HydrophobicContact CD2-CE1 4.11Å; L373-F377 HydrophobicContact CD2-CE2 4.29Å; L373-F377 HydrophobicContact CD2-CZ 3.53Å; L373-F377 HydrophobicContact CG-CE1 3.66Å; L373-F377 HydrophobicContact CG-CE2 4.08Å; L373-F377 HydrophobicContact CG-CZ 3.42Å; L373-F377 VanDerWaalsContact CG-CZ 3.42Å; L373-F377 WeakPolarHBondContact O-CD1 2.93Å; L373-F377 WeakPolarHBondContact O-CG 3.3Å; L373-F377 PolarHBondContact O-N 3.24Å; L373-F377 VanDerWaalsContact O-N 3.09Å; E374-F377 WeakPolarHBondContact O-CB 3.18Å; E374-F377 PolarHBondContact O-N 3.48Å; E374-F377 VanDerWaalsContact O-N 3.16Å; K375-F377 VanDerWaalsContact C-N 3.32Å; F377-Y379 VanDerWaalsContact C-N 3.25Å; F377-Y379 PolarHBondContact O-N 2.74Å; F377-S380 WeakPolarHBondContact O-CB 3.35Å; F377-S380 PolarHBondContact O-N 3.31Å; F377-S380 VanDerWaalsContact O-N 3.09Å; F377-E381 PolarHBondContact O-N 3.1Å
378D98.2Very high97.8Very high44 Ų4445.6 Ų45.624%0.23525%0.252CS..Hα-helixtrans-55.3-43.2174.9-68.6-21.9000111.1P75 F138 E374 K375 Y382P75-D378 HydrophobicContact CB-CB 4.25Å; P75-D378 HydrophobicContact CG-CB 4.22Å; P75-D378 WeakPolarHBondContact CG-O 3.43Å; F138-D378 HydrophobicContact CE1-CB 4.19Å; F138-D378 HydrophobicContact CE2-CB 4.2Å; F138-D378 HydrophobicContact CZ-CB 3.53Å; E374-D378 PolarHBondContact O-N 3.28Å; K375-D378 IonicContact NZ-OD2 2.95Å; K375-D378 PolarHBondContact NZ-OD2 2.88Å; D378-Y382 PolarHBondContact O-N 2.96Å
379Y98.5Very high97.7Very high0 Ų043.1 Ų43.10%024%0.239CC..Hα-helixtrans-64.6-42.8177.2-170.2-152.1000111.9D112 T114 F115 I135 F138 V139 F143 V343 M355 K375 V376 F377 W383D112-Y379 WeakPolarHBondContact OD2-CE1 3.33Å; D112-Y379 PolarHBondContact OD2-OH 3.48Å; T114-Y379 WeakPolarHBondContact CB-OH 3.39Å; F115-Y379 VanDerWaalsContact CE1-OH 3.28Å; F115-Y379 WeakPolarHBondContact CE1-OH 3.3Å; I135-Y379 HydrophobicContact CD1-CD2 4.22Å; I135-Y379 HydrophobicContact CG1-CD2 3.72Å; I135-Y379 HydrophobicContact CG1-CE2 3.67Å; I135-Y379 HydrophobicContact CG2-CE2 4.42Å; F138-Y379 HydrophobicContact CD1-CD2 4.47Å; V139-Y379 HydrophobicContact CG2-CD2 4.39Å; V139-Y379 HydrophobicContact CG2-CE2 3.68Å; F143-Y379 HydrophobicContact CE1-CD1 4.44Å; F143-Y379 HydrophobicContact CE2-CD1 4.02Å; F143-Y379 HydrophobicContact CE2-CG 4.12Å; F143-Y379 AromaticContact CZ-CD1 3.76Å; F143-Y379 HydrophobicContact CZ-CD1 3.76Å; F143-Y379 HydrophobicContact CZ-CG 4.13Å; V343-Y379 HydrophobicContact CB-CD1 3.61Å; V343-Y379 HydrophobicContact CB-CE1 3.64Å; V343-Y379 HydrophobicContact CB-CG 4.32Å; V343-Y379 HydrophobicContact CG1-CD1 4.39Å; V343-Y379 HydrophobicContact CG1-CE1 4.2Å; V343-Y379 HydrophobicContact CG2-CD1 3.36Å; V343-Y379 HydrophobicContact CG2-CE1 3.95Å; V343-Y379 HydrophobicContact CG2-CG 3.73Å; M355-Y379 HydrophobicContact CE-CE1 4.44Å; K375-Y379 WeakPolarHBondContact O-CB 3.47Å; K375-Y379 PolarHBondContact O-N 3.07Å; V376-Y379 PolarHBondContact O-N 2.9Å; F377-Y379 VanDerWaalsContact C-N 3.25Å; F377-Y379 PolarHBondContact O-N 2.74Å; Y379-W383 AromaticContact CD2-CD1 3.59Å; Y379-W383 AromaticContact CD2-NE1 3.71Å; Y379-W383 AromaticContact CE2-CD1 3.34Å; Y379-W383 AromaticContact CE2-NE1 2.96Å; Y379-W383 AromaticContact CZ-CD1 3.85Å; Y379-W383 AromaticContact CZ-NE1 3.38Å; Y379-W383 PolarHBondContact O-N 3.02Å; Y379-W383 PolarHBondContact OH-NE1 2.56Å
380S98.5Very high97.6Very high19 Ų1943 Ų4313%0.13324%0.237CC..Hα-helixtrans-66.1-40180-170.30000112.1V343 S345 V376 F377 Y382 W383 E384V343-S380 VanDerWaalsContact CG2-CA 3.5Å; S345-S380 WeakPolarHBondContact CB-O 3.19Å; S345-S380 PolarHBondContact N-OG 3.44Å; S345-S380 PolarHBondContact OG-O 3.02Å; S345-S380 PolarHBondContact OG-OG 2.83Å; V376-S380 VanDerWaalsContact O-CB 3.31Å; V376-S380 WeakPolarHBondContact O-CB 3.36Å; V376-S380 PolarHBondContact O-N 2.88Å; F377-S380 WeakPolarHBondContact O-CB 3.35Å; F377-S380 PolarHBondContact O-N 3.31Å; F377-S380 VanDerWaalsContact O-N 3.09Å; S380-Y382 PolarHBondContact O-N 2.79Å; S380-W383 CarbonylContact O-C 3.47Å; S380-W383 PolarHBondContact O-N 2.91Å; S380-W383 VanDerWaalsContact O-N 3.13Å; S380-E384 WeakPolarHBondContact O-CB 3.44Å; S380-E384 PolarHBondContact O-N 3.31Å
381E97.9Very high97.5Very high134 Ų13441.3 Ų41.363%0.62622%0.218SC*.Hα-helixtrans-61.9-42.2178.8-174.3174.5-168.500112F377 W383 E384 V385F377-E381 PolarHBondContact O-N 3.1Å; E381-W383 VanDerWaalsContact C-N 3.32Å; E381-W383 PolarHBondContact O-N 3.11Å; E381-E384 PolarHBondContact O-N 3.26Å; E381-V385 PolarHBondContact O-N 3.45Å
382Y98.5Very high97.2Very high2 Ų240.7 Ų40.71%0.00821%0.214CC..Hα-helixtrans-56.7-48.4172.1172.7-95.8000111.4P72 V73 V74 D131 K134 I135 D378 S380 T386P72-Y382 HydrophobicContact CB-CD2 3.86Å; P72-Y382 HydrophobicContact CB-CE2 3.67Å; P72-Y382 HydrophobicContact CG-CE2 3.88Å; V73-Y382 WeakPolarHBondContact O-CD2 3.37Å; V74-Y382 HydrophobicContact CG2-CD2 4.37Å; V74-Y382 HydrophobicContact CG2-CE2 3.94Å; D131-Y382 PolarHBondContact O-OH 3.01Å; K134-Y382 HydrophobicContact CB-CE2 4.44Å; K134-Y382 WeakPolarHBondContact CB-OH 3.29Å; I135-Y382 HydrophobicContact CB-CD1 3.71Å; I135-Y382 HydrophobicContact CB-CE1 3.47Å; I135-Y382 VanDerWaalsContact CB-CE1 3.47Å; I135-Y382 HydrophobicContact CB-CE2 4.42Å; I135-Y382 HydrophobicContact CB-CG 4.28Å; I135-Y382 HydrophobicContact CD1-CD1 3.73Å; I135-Y382 HydrophobicContact CD1-CD2 4.02Å; I135-Y382 HydrophobicContact CD1-CE1 4.34Å; I135-Y382 HydrophobicContact CD1-CG 3.54Å; I135-Y382 HydrophobicContact CG1-CD1 3.59Å; I135-Y382 HydrophobicContact CG1-CE1 3.93Å; I135-Y382 HydrophobicContact CG1-CG 3.98Å; I135-Y382 HydrophobicContact CG2-CD1 4.18Å; I135-Y382 HydrophobicContact CG2-CE1 3.72Å; D378-Y382 PolarHBondContact O-N 2.96Å; S380-Y382 PolarHBondContact O-N 2.79Å; Y382-T386 HydrophobicContact CE1-CG2 4.38Å; Y382-T386 WeakPolarHBondContact CE1-OG1 3.25Å; Y382-T386 VanDerWaalsContact O-CB 3.29Å; Y382-T386 WeakPolarHBondContact O-CB 3.46Å; Y382-T386 PolarHBondContact O-N 2.9Å; Y382-T386 PolarHBondContact O-OG1 3.14Å
383W98.5Very high97Very high1 Ų138.1 Ų38.10%0.00419%0.193CC..Hα-helixtrans-72.7-28.4-176.8-82.9111.4000113.5T114 F115 V127 L132 I135 V343 S345 M346 Y379 S380 E381 T386 R387T114-W383 HydrophobicContact CG2-CD2 3.87Å; T114-W383 HydrophobicContact CG2-CG 4.22Å; T114-W383 HydrophobicContact CG2-CH2 4.43Å; T114-W383 HydrophobicContact CG2-CZ2 3.72Å; F115-W383 HydrophobicContact CD1-CZ2 4.36Å; F115-W383 HydrophobicContact CE1-CZ2 4.13Å; V127-W383 HydrophobicContact CG1-CH2 3.81Å; V127-W383 HydrophobicContact CG1-CZ3 3.99Å; V127-W383 HydrophobicContact CG2-CZ3 4.33Å; L132-W383 HydrophobicContact CD2-CH2 3.69Å; L132-W383 HydrophobicContact CD2-CZ2 3.99Å; I135-W383 HydrophobicContact CG2-CZ2 4.08Å; V343-W383 HydrophobicContact CG1-CB 4.03Å; V343-W383 HydrophobicContact CG1-CG 3.86Å; S345-W383 WeakPolarHBondContact OG-CB 3.43Å; M346-W383 HydrophobicContact CE-CE3 4.32Å; M346-W383 HydrophobicContact CE-CZ3 4.43Å; M346-W383 HydrophobicContact CG-CB 3.89Å; M346-W383 HydrophobicContact CG-CD2 4.03Å; M346-W383 HydrophobicContact CG-CE3 3.96Å; M346-W383 HydrophobicContact CG-CG 4.03Å; M346-W383 HydrophobicContact SD-CE3 4.11Å; Y379-W383 AromaticContact CD2-CD1 3.59Å; Y379-W383 AromaticContact CD2-NE1 3.71Å; Y379-W383 AromaticContact CE2-CD1 3.34Å; Y379-W383 AromaticContact CE2-NE1 2.96Å; Y379-W383 AromaticContact CZ-CD1 3.85Å; Y379-W383 AromaticContact CZ-NE1 3.38Å; Y379-W383 PolarHBondContact O-N 3.02Å; Y379-W383 PolarHBondContact OH-NE1 2.56Å; S380-W383 CarbonylContact O-C 3.47Å; S380-W383 PolarHBondContact O-N 2.91Å; S380-W383 VanDerWaalsContact O-N 3.13Å; E381-W383 VanDerWaalsContact C-N 3.32Å; E381-W383 PolarHBondContact O-N 3.11Å; W383-T386 HydrophobicContact CE3-CG2 3.85Å; W383-T386 HydrophobicContact CZ3-CG2 3.75Å; W383-T386 PolarHBondContact O-N 3.34Å; W383-R387 WeakPolarHBondContact O-CB 3.25Å; W383-R387 PolarHBondContact O-N 3.25Å
384E97.2Very high96.7Very high120 Ų12036.6 Ų36.656%0.56119%0.185SC*.Hα-helixtrans-60.4-49174.4-174.566-156.700110.3S345 S380 E381S345-E384 WeakPolarHBondContact CB-OE2 3.18Å; S345-E384 PolarHBondContact OG-N 3.24Å; S380-E384 WeakPolarHBondContact O-CB 3.44Å; S380-E384 PolarHBondContact O-N 3.31Å; E381-E384 PolarHBondContact O-N 3.26Å
385V97.6Very high96.2Very high45 Ų4530.3 Ų30.327%0.27316%0.156SC..Hα-helixtrans-70.3-42.7177.1-176.60000111T70 P72 E381 R387 G388T70-V385 HydrophobicContact CG2-CG1 3.96Å; P72-V385 HydrophobicContact CB-CB 4.12Å; P72-V385 HydrophobicContact CB-CG1 4.07Å; E381-V385 PolarHBondContact O-N 3.45Å; V385-R387 PolarHBondContact O-N 2.68Å; V385-G388 PolarHBondContact O-N 3.16Å; V385-G388 VanDerWaalsContact O-N 3.11Å
386T98.2Very high95.7Very high0 Ų029.5 Ų29.50%016%0.156CC..Hα-helixtrans-60.9-43.4-180-60.80000111.7P72 D131 Y382 W383 G388 L389 Y390P72-T386 WeakPolarHBondContact CB-OG1 3.4Å; P72-T386 WeakPolarHBondContact CG-OG1 3.09Å; D131-T386 HydrophobicContact CB-CG2 3.83Å; Y382-T386 HydrophobicContact CE1-CG2 4.38Å; Y382-T386 WeakPolarHBondContact CE1-OG1 3.25Å; Y382-T386 VanDerWaalsContact O-CB 3.29Å; Y382-T386 WeakPolarHBondContact O-CB 3.46Å; Y382-T386 PolarHBondContact O-N 2.9Å; Y382-T386 PolarHBondContact O-OG1 3.14Å; W383-T386 HydrophobicContact CE3-CG2 3.85Å; W383-T386 HydrophobicContact CZ3-CG2 3.75Å; W383-T386 PolarHBondContact O-N 3.34Å; T386-G388 PolarHBondContact O-N 3.09Å; T386-L389 VanDerWaalsContact O-CB 3.22Å; T386-L389 WeakPolarHBondContact O-CB 3.35Å; T386-L389 WeakPolarHBondContact O-CG 3.18Å; T386-L389 PolarHBondContact O-N 3.07Å; T386-Y390 HydrophobicContact CG2-CE2 3.99Å; T386-Y390 VanDerWaalsContact O-CD2 3.28Å; T386-Y390 WeakPolarHBondContact O-CD2 3.44Å
387R97.1Very high94.8Very high31 Ų3131.9 Ų31.912%0.11718%0.175CC..Hα-helixtrans-57.2-34.5176.2-177.5175.1176.9166.13.1111.8L123 S345 M346 W383 V385 L389 Y390 A391 D394L123-R387 HydrophobicContact CD1-CG 4.5Å; L123-R387 HydrophobicContact CD2-CG 4.25Å; S345-R387 WeakPolarHBondContact O-CD 3.5Å; S345-R387 PolarHBondContact O-NH1 2.83Å; M346-R387 HydrophobicContact SD-CB 4.11Å; M346-R387 HydrophobicContact SD-CG 4.19Å; W383-R387 WeakPolarHBondContact O-CB 3.25Å; W383-R387 PolarHBondContact O-N 3.25Å; V385-R387 PolarHBondContact O-N 2.68Å; R387-L389 PolarHBondContact O-N 2.9Å; R387-Y390 CarbonylContact O-C 3.57Å; R387-Y390 WeakPolarHBondContact O-CA 3.3Å; R387-Y390 PolarHBondContact O-N 3.37Å; R387-A391 PolarHBondContact O-N 3.39Å; R387-D394 IonicContact CZ-OD1 3.63Å; R387-D394 IonicContact CZ-OD2 2.64Å; R387-D394 IonicContact NE-OD1 3.58Å; R387-D394 IonicContact NE-OD2 3.66Å; R387-D394 PolarHBondContact NE-OD2 2.64Å; R387-D394 IonicContact NH2-OD1 2.8Å; R387-D394 PolarHBondContact NH2-OD1 2.9Å; R387-D394 IonicContact NH2-OD2 3.39Å; R387-D394 PolarHBondContact NH2-OD2 2.77Å
388G96.7Very high93.6Very high24 Ų2429 Ų2925%0.24717%0.167CC..Hα-helixtrans-57.5-30.7172.400000114.2S68 V385 T386 Y390 A391S68-G388 WeakPolarHBondContact CB-O 3.5Å; S68-G388 PolarHBondContact N-O 3.4Å; V385-G388 PolarHBondContact O-N 3.16Å; V385-G388 VanDerWaalsContact O-N 3.11Å; T386-G388 PolarHBondContact O-N 3.09Å; G388-Y390 PolarHBondContact O-N 3.24Å; G388-A391 WeakPolarHBondContact O-CB 3.4Å; G388-A391 PolarHBondContact O-N 3.5Å
389L96.4Very high92.7Very high4 Ų427.7 Ų27.72%0.02116%0.159CC..Hα-helixtrans-66.5-24.2173.6-55.7174.3000112.1P67 S68 P72 T386 R387 T580 R581P67-L389 VanDerWaalsContact CB-O 3.31Å; P67-L389 WeakPolarHBondContact CB-O 3.31Å; S68-L389 WeakPolarHBondContact O-CD2 3.41Å; P72-L389 HydrophobicContact CG-CD1 4.36Å; T386-L389 VanDerWaalsContact O-CB 3.22Å; T386-L389 WeakPolarHBondContact O-CB 3.35Å; T386-L389 WeakPolarHBondContact O-CG 3.18Å; T386-L389 PolarHBondContact O-N 3.07Å; R387-L389 PolarHBondContact O-N 2.9Å; L389-T580 HydrophobicContact CB-CG2 3.97Å; L389-R581 HydrophobicContact CD2-CB 4.46Å
390Y96.3Very high92.1Very high2 Ų235.8 Ų35.81%0.00820%0.195CC..THydrogen-bonded Turntrans-103.212.5-178.6-61.1-81.1000113.5L123 R126 V127 R128 D131 T386 R387 G388 P392 F393 D394 T580L123-Y390 HydrophobicContact CD1-CD2 4.18Å; L123-Y390 HydrophobicContact CD1-CG 4.02Å; R126-Y390 HydrophobicContact CB-CD1 4.19Å; R126-Y390 HydrophobicContact CB-CE1 4.5Å; R126-Y390 WeakPolarHBondContact O-CE1 3.47Å; V127-Y390 HydrophobicContact CG2-CD2 4.24Å; V127-Y390 HydrophobicContact CG2-CE1 4.44Å; V127-Y390 HydrophobicContact CG2-CE2 4.04Å; R128-Y390 WeakPolarHBondContact CB-OH 3.08Å; R128-Y390 HydrophobicContact CG-CE1 4.48Å; R128-Y390 PolarHBondContact N-OH 3.39Å; D131-Y390 WeakPolarHBondContact OD2-CE2 3.48Å; D131-Y390 PolarHBondContact OD2-OH 2.89Å; T386-Y390 HydrophobicContact CG2-CE2 3.99Å; T386-Y390 VanDerWaalsContact O-CD2 3.28Å; T386-Y390 WeakPolarHBondContact O-CD2 3.44Å; R387-Y390 CarbonylContact O-C 3.57Å; R387-Y390 WeakPolarHBondContact O-CA 3.3Å; R387-Y390 PolarHBondContact O-N 3.37Å; G388-Y390 PolarHBondContact O-N 3.24Å; Y390-P392 WeakPolarHBondContact O-CD 3.26Å; Y390-F393 HydrophobicContact CD1-CD2 4.25Å; Y390-F393 PolarHBondContact O-N 3.11Å; Y390-D394 PolarHBondContact O-N 3.44Å; Y390-T580 HydrophobicContact CD1-CG2 4.36Å; Y390-T580 HydrophobicContact CE1-CG2 3.65Å; Y390-T580 HydrophobicContact CE2-CG2 4.08Å; Y390-T580 VanDerWaalsContact CZ-CG2 3.5Å; Y390-T580 PolarHBondContact OH-OG1 3.21Å
391A94.2Very high91.7Very high26 Ų2638.5 Ų38.522%0.21521%0.214CC..G310 helixtrans-46.4-35174.400000114.8A65 R387 G388 F393 D394A65-A391 HydrophobicContact CB-CB 4.17Å; A65-A391 WeakPolarHBondContact CB-O 3.09Å; R387-A391 PolarHBondContact O-N 3.39Å; G388-A391 WeakPolarHBondContact O-CB 3.4Å; G388-A391 PolarHBondContact O-N 3.5Å; A391-F393 PolarHBondContact O-N 3.44Å; A391-F393 VanDerWaalsContact O-N 3.12Å; A391-D394 PolarHBondContact O-N 2.94Å
392P91.6Very high91.2Very high0 Ų033.5 Ų33.50%020%0.198CC..G310 helixtrans-62.3-12.9174.1-20.531.5000115.6I61 P62 V63 A65 P67 Y390I61-P392 HydrophobicContact CD1-CB 4.16Å; I61-P392 HydrophobicContact CG1-CB 4.17Å; I61-P392 HydrophobicContact CG2-CB 3.72Å; P62-P392 WeakPolarHBondContact CD-O 3.29Å; P62-P392 VanDerWaalsContact CG-O 3.29Å; P62-P392 WeakPolarHBondContact CG-O 3.29Å; V63-P392 VanDerWaalsContact CG2-C 3.48Å; V63-P392 WeakPolarHBondContact CG2-O 3.49Å; A65-P392 WeakPolarHBondContact O-CG 3.29Å; P67-P392 HydrophobicContact CG-CG 3.92Å; Y390-P392 WeakPolarHBondContact O-CD 3.26Å
393F92Very high90.7Very high3 Ų335.7 Ų35.71%0.01321%0.21CC..G310 helixtrans-119.9-2.4-178.2-51.6-70.3000113.2T59 P60 I61 P62 R126 Y390 A391 C395 L584T59-F393 HydrophobicContact CG2-CE1 3.97Å; T59-F393 HydrophobicContact CG2-CZ 3.74Å; P60-F393 WeakPolarHBondContact O-CE1 3.2Å; I61-F393 HydrophobicContact CG1-CE1 4.39Å; I61-F393 HydrophobicContact CG1-CZ 4.3Å; P62-F393 VanDerWaalsContact CD-CD1 3.48Å; P62-F393 HydrophobicContact CG-CD1 4.02Å; R126-F393 HydrophobicContact CB-CB 4.47Å; R126-F393 HydrophobicContact CB-CD2 3.81Å; R126-F393 HydrophobicContact CB-CE2 4.14Å; R126-F393 HydrophobicContact CB-CG 4.03Å; R126-F393 HydrophobicContact CG-CB 4.24Å; R126-F393 HydrophobicContact CG-CD1 3.75Å; R126-F393 HydrophobicContact CG-CD2 3.91Å; R126-F393 HydrophobicContact CG-CE1 4.03Å; R126-F393 HydrophobicContact CG-CE2 4.17Å; R126-F393 HydrophobicContact CG-CG 3.69Å; R126-F393 HydrophobicContact CG-CZ 4.23Å; Y390-F393 HydrophobicContact CD1-CD2 4.25Å; Y390-F393 PolarHBondContact O-N 3.11Å; A391-F393 PolarHBondContact O-N 3.44Å; A391-F393 VanDerWaalsContact O-N 3.12Å; F393-C395 PolarHBondContact O-N 3.2Å; F393-L584 HydrophobicContact CE2-CD1 3.87Å; F393-L584 HydrophobicContact CE2-CD2 3.85Å; F393-L584 HydrophobicContact CZ-CD2 3.97Å
394D92.2Very high90.4Very high12 Ų1238.4 Ų38.46%0.06423%0.232CC..  trans-71.3127.7-171.3-161.5-49.3000111.6L123 R387 Y390 A391 T396 A397L123-D394 HydrophobicContact CD2-CB 3.92Å; R387-D394 IonicContact CZ-OD1 3.63Å; R387-D394 IonicContact CZ-OD2 2.64Å; R387-D394 IonicContact NE-OD1 3.58Å; R387-D394 IonicContact NE-OD2 3.66Å; R387-D394 PolarHBondContact NE-OD2 2.64Å; R387-D394 IonicContact NH2-OD1 2.8Å; R387-D394 PolarHBondContact NH2-OD1 2.9Å; R387-D394 IonicContact NH2-OD2 3.39Å; R387-D394 PolarHBondContact NH2-OD2 2.77Å; Y390-D394 PolarHBondContact O-N 3.44Å; A391-D394 PolarHBondContact O-N 2.94Å; D394-T396 PolarHBondContact O-N 2.89Å; D394-T396 VanDerWaalsContact O-N 3.08Å; D394-T396 VanDerWaalsContact OD1-CB 3.27Å; D394-T396 WeakPolarHBondContact OD1-CB 3.49Å; D394-T396 VanDerWaalsContact OD1-CG2 3.22Å; D394-T396 WeakPolarHBondContact OD1-CG2 3.31Å; D394-T396 PolarHBondContact OD1-N 3.38Å; D394-T396 PolarHBondContact OD1-OG1 2.9Å; D394-A397 VanDerWaalsContact O-CB 3.27Å; D394-A397 WeakPolarHBondContact O-CB 3.06Å; D394-A397 PolarHBondContact O-N 3.23Å
395C87.3Confident90.2Very high1 Ų134.8 Ų34.81%0.00722%0.217CC..G310 helixtrans-56.6-26.417769.80000111.8L122 F393 A397 T398 M399 T417L122-C395 PolarHBondContact O-N 2.8Å; F393-C395 PolarHBondContact O-N 3.2Å; C395-A397 PolarHBondContact O-N 3.27Å; C395-T398 CarbonylContact O-C 3.42Å; C395-T398 PolarHBondContact O-N 3.38Å; C395-T398 PolarHBondContact O-OG1 3.43Å; C395-M399 PolarHBondContact O-N 3.13Å; C395-T417 HydrophobicContact CB-CG2 4.17Å
396T87.1Confident90.1Very high42 Ų4232.7 Ų32.726%0.25820%0.204SC..G310 helixtrans-66.9-14.3177.764.50000115M349 D394 T398 M399 K400M349-T396 HydrophobicContact CE-CG2 3.54Å; M349-T396 HydrophobicContact SD-CG2 3.86Å; D394-T396 PolarHBondContact O-N 2.89Å; D394-T396 VanDerWaalsContact O-N 3.08Å; D394-T396 VanDerWaalsContact OD1-CB 3.27Å; D394-T396 WeakPolarHBondContact OD1-CB 3.49Å; D394-T396 VanDerWaalsContact OD1-CG2 3.22Å; D394-T396 WeakPolarHBondContact OD1-CG2 3.31Å; D394-T396 PolarHBondContact OD1-N 3.38Å; D394-T396 PolarHBondContact OD1-OG1 2.9Å; T396-T398 PolarHBondContact O-N 2.89Å; T396-T398 VanDerWaalsContact O-N 3.14Å; T396-M399 VanDerWaalsContact CA-O 3.25Å; T396-M399 WeakPolarHBondContact CA-O 3.47Å; T396-K400 WeakPolarHBondContact O-CD 3.27Å; T396-K400 WeakPolarHBondContact O-CE 3.4Å; T396-K400 PolarHBondContact O-NZ 3.29Å
397A79.6Confident89.9Confident50 Ų5036.3 Ų36.341%0.41322%0.219SC..G310 helixtrans-59.7-21.316600000111.8V63 D394 C395V63-A397 HydrophobicContact CB-CB 3.9Å; V63-A397 HydrophobicContact CG1-CB 3.74Å; V63-A397 HydrophobicContact CG2-CB 3.67Å; D394-A397 VanDerWaalsContact O-CB 3.27Å; D394-A397 WeakPolarHBondContact O-CB 3.06Å; D394-A397 PolarHBondContact O-N 3.23Å; C395-A397 PolarHBondContact O-N 3.27Å
398T71.9Confident89.7Confident50 Ų5042.6 Ų42.631%0.30725%0.249SC..THydrogen-bonded Turntrans-130.3-23.8-171.165.50000114.1V63 C395 T396 H420 F421V63-T398 HydrophobicContact CG1-CG2 4.2Å; C395-T398 CarbonylContact O-C 3.42Å; C395-T398 PolarHBondContact O-N 3.38Å; C395-T398 PolarHBondContact O-OG1 3.43Å; T396-T398 PolarHBondContact O-N 2.89Å; T396-T398 VanDerWaalsContact O-N 3.14Å; T398-H420 WeakPolarHBondContact CB-CE1 3.46Å; T398-H420 WeakPolarHBondContact CB-ND1 3.41Å; T398-H420 WeakPolarHBondContact CG2-CE1 3.28Å; T398-H420 WeakPolarHBondContact CG2-ND1 3.49Å; T398-H420 PolarHBondContact OG1-ND1 2.97Å; T398-F421 HydrophobicContact CG2-CE1 4.49Å
399M79.8Confident89.6Confident15 Ų1541.8 Ų41.87%0.07424%0.239CC..  trans-135.8110-179.4-179.1-179.268.900110.6M349 T350 C395 T396 S401 Y416M349-M399 HydrophobicContact CB-CE 3.89Å; M349-M399 HydrophobicContact CG-CE 4.48Å; M349-M399 HydrophobicContact SD-CE 4.3Å; T350-M399 HydrophobicContact CG2-CE 3.88Å; C395-M399 PolarHBondContact O-N 3.13Å; T396-M399 VanDerWaalsContact CA-O 3.25Å; T396-M399 WeakPolarHBondContact CA-O 3.47Å; M399-S401 WeakPolarHBondContact CG-O 3.41Å; M399-Y416 HydrophobicContact CE-CE1 4.43Å; M399-Y416 HydrophobicContact SD-CD1 4.16Å; M399-Y416 HydrophobicContact SD-CE1 3.49Å; M399-Y416 WeakPolarHBondContact SD-CE1 3.45Å
400K86.3Confident89.6Confident170 Ų17041.9 Ų41.974%0.73924%0.24SC*.SBendtrans-79.8-14.7-173.6-60.4-58-177.8-170.20115.1T396T396-K400 WeakPolarHBondContact O-CD 3.27Å; T396-K400 WeakPolarHBondContact O-CE 3.4Å; T396-K400 PolarHBondContact O-NZ 3.29Å
401S89.9Confident89.5Confident77 Ų7741.9 Ų41.954%0.53824%0.239SC..SBendtrans-157.2172.5-177.364.30000110.5M399M399-S401 WeakPolarHBondContact CG-O 3.41Å
402G86.1Confident89.4Confident28 Ų2841 Ų4129%0.28923%0.232SC..  trans-57.5163.916700000112.7T320T320-G402 CarbonylContact O-C 3.55Å; T320-G402 VanDerWaalsContact O-C 3.3Å; T320-G402 WeakPolarHBondContact O-CA 3.15Å
403N88.6Confident88.9Confident49 Ų4941 Ų4126%0.26223%0.232SC..  trans-140.7120.8-179.3-169.4-11.5000111.7T320 D405 V406 K436T320-N403 PolarHBondContact O-N 3.49Å; N403-D405 PolarHBondContact ND2-OD1 2.95Å; N403-D405 VanDerWaalsContact ND2-OD1 3.11Å; N403-D405 PolarHBondContact ND2-OD2 3.29Å; N403-D405 PolarHBondContact O-N 3.23Å; N403-D405 PolarHBondContact OD1-N 2.79Å; N403-D405 PolarHBondContact OD1-OD1 3.11Å; N403-D405 PolarHBondContact OD1-OD2 3.37Å; N403-V406 WeakPolarHBondContact O-CG1 3.35Å; N403-K436 PolarHBondContact ND2-NZ 3.28Å; N403-K436 VanDerWaalsContact ND2-NZ 3.2Å
404A92.9Very high88.4Confident57 Ų5741.4 Ų41.447%0.47124%0.236SC..THydrogen-bonded Turntrans-73.8-10.8-179.300000113.9V406 Y407A404-V406 PolarHBondContact O-N 2.88Å; A404-Y407 HydrophobicContact CB-CD2 4.39Å; A404-Y407 HydrophobicContact CB-CE2 4.45Å; A404-Y407 WeakPolarHBondContact O-CD2 3.18Å; A404-Y407 PolarHBondContact O-N 3.22Å; A404-Y407 VanDerWaalsContact O-N 3.14Å
405D92.4Very high88.1Confident44 Ų4441.4 Ų41.424%0.23524%0.236CC..THydrogen-bonded Turntrans-64-9.3174.369.415.6000113.5N403 Y407 E408 N409 K436N403-D405 PolarHBondContact ND2-OD1 2.95Å; N403-D405 VanDerWaalsContact ND2-OD1 3.11Å; N403-D405 PolarHBondContact ND2-OD2 3.29Å; N403-D405 PolarHBondContact O-N 3.23Å; N403-D405 PolarHBondContact OD1-N 2.79Å; N403-D405 PolarHBondContact OD1-OD1 3.11Å; N403-D405 PolarHBondContact OD1-OD2 3.37Å; D405-Y407 PolarHBondContact O-N 3.13Å; D405-E408 WeakPolarHBondContact O-CB 3.27Å; D405-E408 PolarHBondContact O-N 2.87Å; D405-N409 PolarHBondContact O-N 3.23Å; D405-N409 PolarHBondContact O-ND2 3.37Å; D405-N409 PolarHBondContact OD1-ND2 2.98Å; D405-K436 IonicContact OD1-NZ 3.4Å; D405-K436 WeakPolarHBondContact OD2-CE 3.16Å; D405-K436 IonicContact OD2-NZ 2.59Å; D405-K436 PolarHBondContact OD2-NZ 3.27Å
406V94.8Very high88.1Confident2 Ų242 Ų421%0.01224%0.239CC..Hα-helixtrans-57-28.5169.672.80000112.8A289 L291 T320 A321 N403 A404 E408 E410A289-V406 HydrophobicContact CB-CG2 4.19Å; A289-V406 WeakPolarHBondContact O-CG2 3.5Å; L291-V406 HydrophobicContact CD2-CG2 4.28Å; L291-V406 WeakPolarHBondContact CD2-O 3.43Å; T320-V406 HydrophobicContact CG2-CB 3.95Å; T320-V406 HydrophobicContact CG2-CG1 4.13Å; T320-V406 HydrophobicContact CG2-CG2 4.05Å; A321-V406 HydrophobicContact CB-CG1 3.91Å; N403-V406 WeakPolarHBondContact O-CG1 3.35Å; A404-V406 PolarHBondContact O-N 2.88Å; V406-E408 PolarHBondContact O-N 3.18Å; V406-E410 WeakPolarHBondContact O-CA 3.34Å; V406-E410 PolarHBondContact O-N 2.89Å
407Y95.2Very high87.8Confident76 Ų7640.1 Ų40.130%0.29823%0.227SC..Hα-helixtrans-67.9-17.5173.6-61.7-58.3000113.2L291 K293 A321 A404 D405L291-Y407 HydrophobicContact CD2-CD1 4.19Å; K293-Y407 HydrophobicContact CG-CE1 4.05Å; A321-Y407 HydrophobicContact CB-CD2 4.39Å; A321-Y407 HydrophobicContact CB-CE1 4.46Å; A321-Y407 HydrophobicContact CB-CE2 3.5Å; A321-Y407 WeakPolarHBondContact CB-OH 3.41Å; A404-Y407 HydrophobicContact CB-CD2 4.39Å; A404-Y407 HydrophobicContact CB-CE2 4.45Å; A404-Y407 WeakPolarHBondContact O-CD2 3.18Å; A404-Y407 PolarHBondContact O-N 3.22Å; A404-Y407 VanDerWaalsContact O-N 3.14Å; D405-Y407 PolarHBondContact O-N 3.13Å
408E93.3Very high87.9Confident162 Ų16240.7 Ų40.776%0.75722%0.223SC*.Hα-helixtrans-96.8-45.3174-60.5-175.8176.400112.1D405 V406D405-E408 WeakPolarHBondContact O-CB 3.27Å; D405-E408 PolarHBondContact O-N 2.87Å; V406-E408 PolarHBondContact O-N 3.18Å
409N93.8Very high88.5Confident8 Ų838.3 Ų38.34%0.04321%0.208CC..Hα-helixtrans-91.8-23.5-172.965.664.8000114.1D405 I411 Y439D405-N409 PolarHBondContact O-N 3.23Å; D405-N409 PolarHBondContact O-ND2 3.37Å; D405-N409 PolarHBondContact OD1-ND2 2.98Å; N409-I411 HydrophobicContact CB-CD1 4.09Å; N409-I411 HydrophobicContact CB-CG1 4.12Å; N409-I411 PolarHBondContact O-N 3.43Å; N409-I411 VanDerWaalsContact O-N 3.16Å; N409-I411 VanDerWaalsContact OD1-CB 3.31Å; N409-I411 WeakPolarHBondContact OD1-CB 3.42Å; N409-I411 WeakPolarHBondContact OD1-CD1 3.38Å; N409-I411 WeakPolarHBondContact OD1-CG1 3.42Å; N409-I411 PolarHBondContact OD1-N 3.5Å; N409-Y439 WeakPolarHBondContact O-CD1 3.34Å; N409-Y439 WeakPolarHBondContact O-CE1 3.37Å
410E95.9Very high88.5Confident6 Ų638.3 Ų38.33%0.02821%0.208CC..  trans51.836.3178.6-55.7179.814600113.1G253 R260 L291 V406 P412 K451G253-E410 PolarHBondContact N-OE1 3.45Å; R260-E410 IonicContact CZ-OE1 3.11Å; R260-E410 VanDerWaalsContact CZ-OE1 3.27Å; R260-E410 IonicContact NH1-OE1 3.2Å; R260-E410 PolarHBondContact NH1-OE1 2.73Å; R260-E410 IonicContact NH2-OE1 3.81Å; R260-E410 PolarHBondContact NH2-OE1 2.97Å; R260-E410 IonicContact NH2-OE2 3.32Å; L291-E410 HydrophobicContact CD1-CB 4.09Å; L291-E410 HydrophobicContact CD1-CG 3.8Å; L291-E410 HydrophobicContact CD2-CB 4.4Å; L291-E410 HydrophobicContact CD2-CG 3.99Å; V406-E410 WeakPolarHBondContact O-CA 3.34Å; V406-E410 PolarHBondContact O-N 2.89Å; E410-P412 WeakPolarHBondContact O-CD 3.41Å; E410-K451 WeakPolarHBondContact O-CE 3.22Å; E410-K451 WeakPolarHBondContact OE2-CE 3.38Å; E410-K451 IonicContact OE2-NZ 2.62Å; E410-K451 PolarHBondContact OE2-NZ 2.76Å
411I94.2Very high88.2Confident1 Ų131.7 Ų31.71%0.00518%0.179CC..  trans-77.9121.3175.1-62.6166.4000108.9N409 Q415 Y416 L419 K436 Y439N409-I411 HydrophobicContact CB-CD1 4.09Å; N409-I411 HydrophobicContact CB-CG1 4.12Å; N409-I411 PolarHBondContact O-N 3.43Å; N409-I411 VanDerWaalsContact O-N 3.16Å; N409-I411 VanDerWaalsContact OD1-CB 3.31Å; N409-I411 WeakPolarHBondContact OD1-CB 3.42Å; N409-I411 WeakPolarHBondContact OD1-CD1 3.38Å; N409-I411 WeakPolarHBondContact OD1-CG1 3.42Å; N409-I411 PolarHBondContact OD1-N 3.5Å; I411-Q415 HydrophobicContact CG2-CB 4.17Å; I411-Q415 HydrophobicContact CG2-CG 4.06Å; I411-Y416 HydrophobicContact CB-CD2 4.36Å; I411-Y416 HydrophobicContact CG2-CD2 4.11Å; I411-Y416 HydrophobicContact CG2-CG 4.46Å; I411-L419 HydrophobicContact CD1-CD2 4.1Å; I411-K436 HydrophobicContact CD1-CB 4.4Å; I411-K436 HydrophobicContact CD1-CD 4.42Å; I411-K436 HydrophobicContact CD1-CG 3.86Å; I411-Y439 HydrophobicContact CB-CE1 4.29Å; I411-Y439 HydrophobicContact CD1-CD1 4.13Å; I411-Y439 HydrophobicContact CD1-CD2 4.28Å; I411-Y439 HydrophobicContact CD1-CG 3.96Å; I411-Y439 HydrophobicContact CG1-CD1 3.39Å; I411-Y439 HydrophobicContact CG1-CD2 3.98Å; I411-Y439 HydrophobicContact CG1-CE1 3.42Å; I411-Y439 VanDerWaalsContact CG1-CE1 3.42Å; I411-Y439 HydrophobicContact CG1-CE2 4.06Å; I411-Y439 HydrophobicContact CG1-CG 3.66Å
412P92.3Very high87.7Confident8 Ų830.6 Ų30.65%0.05217%0.166CC..  trans-64.1157.9177.1-24.435.6000113.8M288 E410 G414 Q415 Y416 K451M288-P412 HydrophobicContact CB-CB 4.32Å; M288-P412 HydrophobicContact CG-CB 4.13Å; M288-P412 HydrophobicContact CG-CG 3.97Å; M288-P412 WeakPolarHBondContact O-CA 3.48Å; M288-P412 WeakPolarHBondContact O-CB 3.4Å; E410-P412 WeakPolarHBondContact O-CD 3.41Å; P412-G414 PolarHBondContact O-N 3.24Å; P412-Q415 HydrophobicContact CB-CB 4.32Å; P412-Q415 PolarHBondContact O-N 3.2Å; P412-Q415 VanDerWaalsContact O-N 3.11Å; P412-Y416 PolarHBondContact O-N 3.47Å; P412-K451 HydrophobicContact CG-CB 4.5Å; P412-K451 WeakPolarHBondContact CG-O 3.27Å
413G82.3Confident87.4Confident1 Ų129.3 Ų29.31%0.0115%0.152CC..Hα-helixtrans-49.9-63.8-175.900000114.2M288 Q415 Y416M288-G413 PolarHBondContact O-N 2.6Å; G413-Q415 VanDerWaalsContact C-N 3.27Å; G413-Q415 PolarHBondContact O-N 2.83Å; G413-Y416 WeakPolarHBondContact O-CB 3.5Å; G413-Y416 PolarHBondContact O-N 3.11Å; G413-Y416 VanDerWaalsContact O-N 3.13Å
414G80.4Confident86.9Confident10 Ų1031.5 Ų31.510%0.10316%0.161CC..Hα-helixtrans-60.9-32178.700000114.2P412 N418P412-G414 PolarHBondContact O-N 3.24Å; G414-N418 WeakPolarHBondContact O-CB 3.42Å; G414-N418 PolarHBondContact O-N 2.85Å; G414-N418 PolarHBondContact O-ND2 3.29Å; G414-N418 VanDerWaalsContact O-ND2 3.11Å
415Q86.7Confident86.1Confident12 Ų1233.6 Ų33.66%0.05617%0.172CC..Hα-helixtrans-71.2-33.8177-179.761.110.200111.6I411 P412 G413 N418 L419 Y439 S456I411-Q415 HydrophobicContact CG2-CB 4.17Å; I411-Q415 HydrophobicContact CG2-CG 4.06Å; P412-Q415 HydrophobicContact CB-CB 4.32Å; P412-Q415 PolarHBondContact O-N 3.2Å; P412-Q415 VanDerWaalsContact O-N 3.11Å; G413-Q415 VanDerWaalsContact C-N 3.27Å; G413-Q415 PolarHBondContact O-N 2.83Å; Q415-N418 PolarHBondContact O-N 3.1Å; Q415-L419 WeakPolarHBondContact O-CB 3.3Å; Q415-L419 PolarHBondContact O-N 3.36Å; Q415-Y439 HydrophobicContact CG-CE2 4.5Å; Q415-S456 PolarHBondContact NE2-O 3.43Å
416Y85.6Confident85.3Confident15 Ų1535.9 Ų35.96%0.05918%0.182CC..Hα-helixtrans-59.8-51.8178.5-168.6-82.7000111.2T350 M399 I411 P412 G413 N418 L419 H420 F432 K436T350-Y416 HydrophobicContact CG2-CD1 4.34Å; T350-Y416 HydrophobicContact CG2-CG 4.28Å; M399-Y416 HydrophobicContact CE-CE1 4.43Å; M399-Y416 HydrophobicContact SD-CD1 4.16Å; M399-Y416 HydrophobicContact SD-CE1 3.49Å; M399-Y416 WeakPolarHBondContact SD-CE1 3.45Å; I411-Y416 HydrophobicContact CB-CD2 4.36Å; I411-Y416 HydrophobicContact CG2-CD2 4.11Å; I411-Y416 HydrophobicContact CG2-CG 4.46Å; P412-Y416 PolarHBondContact O-N 3.47Å; G413-Y416 WeakPolarHBondContact O-CB 3.5Å; G413-Y416 PolarHBondContact O-N 3.11Å; G413-Y416 VanDerWaalsContact O-N 3.13Å; Y416-N418 PolarHBondContact O-N 3.49Å; Y416-L419 PolarHBondContact O-N 3.2Å; Y416-H420 VanDerWaalsContact O-CB 3.29Å; Y416-H420 WeakPolarHBondContact O-CB 3.21Å; Y416-H420 PolarHBondContact O-N 3.42Å; Y416-F432 HydrophobicContact CE1-CE1 4.03Å; Y416-F432 HydrophobicContact CE1-CZ 4.35Å; Y416-F432 AromaticContact CE2-CE1 3.99Å; Y416-F432 HydrophobicContact CE2-CE1 3.99Å; Y416-F432 HydrophobicContact CE2-CZ 4.33Å; Y416-F432 AromaticContact CZ-CE1 3.62Å; Y416-K436 HydrophobicContact CE2-CD 3.91Å
417T82.2Confident84.6Confident2 Ų238.6 Ų38.61%0.01221%0.21CC..Hα-helixtrans-61.4-45.2178.8-59.50000111.2S121 C395 H420 F421S121-T417 PolarHBondContact O-OG1 3.04Å; C395-T417 HydrophobicContact CB-CG2 4.17Å; T417-H420 PolarHBondContact O-N 3.27Å; T417-F421 HydrophobicContact CG2-CD2 4.04Å; T417-F421 HydrophobicContact CG2-CE1 4.48Å; T417-F421 HydrophobicContact CG2-CE2 3.44Å; T417-F421 VanDerWaalsContact CG2-CE2 3.44Å; T417-F421 HydrophobicContact CG2-CZ 3.7Å; T417-F421 WeakPolarHBondContact O-CG 3.5Å; T417-F421 PolarHBondContact O-N 3.29Å
418N82.1Confident83.7Confident62 Ų6235.9 Ų35.933%0.33220%0.201SC..Hα-helixtrans-65.3-46.5178.3-74.7-30.6000113.1G414 Q415 Y416 H420 F421 Q422G414-N418 WeakPolarHBondContact O-CB 3.42Å; G414-N418 PolarHBondContact O-N 2.85Å; G414-N418 PolarHBondContact O-ND2 3.29Å; G414-N418 VanDerWaalsContact O-ND2 3.11Å; Q415-N418 PolarHBondContact O-N 3.1Å; Y416-N418 PolarHBondContact O-N 3.49Å; N418-H420 PolarHBondContact O-N 3.3Å; N418-F421 PolarHBondContact O-N 3.29Å; N418-Q422 WeakPolarHBondContact O-CB 3.36Å; N418-Q422 VanDerWaalsContact O-CG 3.26Å; N418-Q422 WeakPolarHBondContact O-CG 3.34Å; N418-Q422 PolarHBondContact O-N 3.2Å
419L83.6Confident82.9Confident0 Ų028.8 Ų28.80%017%0.172CC..Hα-helixtrans-61.8-37.8179.3-171.375.6000110.7I411 Q415 Y416 A423 F432 V435 Y439 Q464I411-L419 HydrophobicContact CD1-CD2 4.1Å; Q415-L419 WeakPolarHBondContact O-CB 3.3Å; Q415-L419 PolarHBondContact O-N 3.36Å; Y416-L419 PolarHBondContact O-N 3.2Å; L419-A423 VanDerWaalsContact O-CB 3.29Å; L419-A423 WeakPolarHBondContact O-CB 3.43Å; L419-A423 PolarHBondContact O-N 3.11Å; L419-F432 HydrophobicContact CD2-CE2 4.26Å; L419-F432 HydrophobicContact CG-CE2 4.24Å; L419-V435 HydrophobicContact CD1-CG1 4.38Å; L419-V435 HydrophobicContact CD2-CG1 3.77Å; L419-V435 HydrophobicContact CG-CG1 4.06Å; L419-Y439 HydrophobicContact CD2-CD2 4.14Å; L419-Q464 HydrophobicContact CD1-CG 4.14Å
420H80.7Confident82.3Confident15 Ų1535.2 Ų35.27%0.06921%0.206CC..Hα-helixtrans-65.8-48.3175.9-171.4-84.1000111.8T398 Y416 T417 N418 Q422 A423 H424 F432T398-H420 WeakPolarHBondContact CB-CE1 3.46Å; T398-H420 WeakPolarHBondContact CB-ND1 3.41Å; T398-H420 WeakPolarHBondContact CG2-CE1 3.28Å; T398-H420 WeakPolarHBondContact CG2-ND1 3.49Å; T398-H420 PolarHBondContact OG1-ND1 2.97Å; Y416-H420 VanDerWaalsContact O-CB 3.29Å; Y416-H420 WeakPolarHBondContact O-CB 3.21Å; Y416-H420 PolarHBondContact O-N 3.42Å; T417-H420 PolarHBondContact O-N 3.27Å; N418-H420 PolarHBondContact O-N 3.3Å; H420-Q422 VanDerWaalsContact C-N 3.34Å; H420-Q422 PolarHBondContact O-N 3.44Å; H420-A423 PolarHBondContact O-N 3.02Å; H420-H424 AromaticContact CE1-CD2 2.99Å; H420-H424 PolarHBondContact CE1-CD2 3.3Å; H420-H424 AromaticContact CE1-NE2 2.93Å; H420-H424 PolarHBondContact CE1-NE2 3.19Å; H420-H424 AromaticContact ND1-CD2 3.49Å; H420-H424 PolarHBondContact ND1-CD2 3.48Å; H420-H424 AromaticContact ND1-NE2 3.88Å; H420-H424 AromaticContact NE2-CD2 3.52Å; H420-H424 AromaticContact NE2-NE2 3.21Å; H420-H424 PolarHBondContact NE2-NE2 2.95Å; H420-H424 PolarHBondContact O-CD2 2.9Å; H420-H424 PolarHBondContact O-N 3.06Å; H420-F432 VanDerWaalsContact CA-CE2 3.49Å; H420-F432 HydrophobicContact CB-CD2 4.41Å; H420-F432 HydrophobicContact CB-CE2 3.78Å; H420-F432 HydrophobicContact CB-CZ 3.82Å; H420-F432 AromaticContact CD2-CD1 3.68Å; H420-F432 AromaticContact CD2-CD2 3.74Å; H420-F432 AromaticContact CD2-CE1 3.78Å; H420-F432 AromaticContact CD2-CE2 3.85Å; H420-F432 AromaticContact CD2-CG 3.65Å; H420-F432 AromaticContact CD2-CZ 3.87Å
421F79.5Confident81.7Confident30 Ų3037.7 Ų37.713%0.13222%0.217CC..Hα-helixtrans-61.8-40.6176.4-65.8-21.5000112.6P62 V63 A124 T398 T417 N418 H424 S425P62-F421 HydrophobicContact CB-CB 4.15Å; P62-F421 HydrophobicContact CB-CD1 3.69Å; P62-F421 HydrophobicContact CB-CD2 3.74Å; P62-F421 HydrophobicContact CB-CE1 3.94Å; P62-F421 HydrophobicContact CB-CE2 3.97Å; P62-F421 HydrophobicContact CB-CG 3.6Å; P62-F421 HydrophobicContact CB-CZ 4.07Å; P62-F421 HydrophobicContact CG-CD1 4.28Å; P62-F421 HydrophobicContact CG-CD2 3.86Å; P62-F421 HydrophobicContact CG-CE1 4.06Å; P62-F421 HydrophobicContact CG-CE2 3.6Å; P62-F421 HydrophobicContact CG-CG 4.2Å; P62-F421 HydrophobicContact CG-CZ 3.72Å; V63-F421 HydrophobicContact CG1-CE1 3.99Å; A124-F421 HydrophobicContact CB-CE2 4.04Å; T398-F421 HydrophobicContact CG2-CE1 4.49Å; T417-F421 HydrophobicContact CG2-CD2 4.04Å; T417-F421 HydrophobicContact CG2-CE1 4.48Å; T417-F421 HydrophobicContact CG2-CE2 3.44Å; T417-F421 VanDerWaalsContact CG2-CE2 3.44Å; T417-F421 HydrophobicContact CG2-CZ 3.7Å; T417-F421 WeakPolarHBondContact O-CG 3.5Å; T417-F421 PolarHBondContact O-N 3.29Å; N418-F421 PolarHBondContact O-N 3.29Å; F421-H424 PolarHBondContact O-N 3.29Å; F421-S425 PolarHBondContact O-N 3.36Å
422Q80.1Confident81.2Confident55 Ų5538.4 Ų38.426%0.25722%0.22SC..Hα-helixtrans-61.4-48.8173.4-72.3169.28.200111.3N418 H420 H424 S425 M426N418-Q422 WeakPolarHBondContact O-CB 3.36Å; N418-Q422 VanDerWaalsContact O-CG 3.26Å; N418-Q422 WeakPolarHBondContact O-CG 3.34Å; N418-Q422 PolarHBondContact O-N 3.2Å; H420-Q422 VanDerWaalsContact C-N 3.34Å; H420-Q422 PolarHBondContact O-N 3.44Å; Q422-H424 VanDerWaalsContact C-N 3.3Å; Q422-H424 PolarHBondContact O-N 3.44Å; Q422-S425 PolarHBondContact O-N 3.5Å; Q422-S425 VanDerWaalsContact O-N 3.1Å; Q422-S425 PolarHBondContact O-OG 2.84Å; Q422-M426 WeakPolarHBondContact O-CG 3.48Å; Q422-M426 PolarHBondContact O-N 2.95Å
423A79.8Confident81.1Confident0 Ų045.3 Ų45.30%025%0.249CC..Hα-helixtrans-57.4-42.2178.200000112L419 H420 M426 G427 L428 G429 F432L419-A423 VanDerWaalsContact O-CB 3.29Å; L419-A423 WeakPolarHBondContact O-CB 3.43Å; L419-A423 PolarHBondContact O-N 3.11Å; H420-A423 PolarHBondContact O-N 3.02Å; A423-M426 PolarHBondContact O-N 3.48Å; A423-G427 PolarHBondContact O-N 2.86Å; A423-L428 HydrophobicContact CB-CB 4.22Å; A423-L428 CarbonylContact O-C 3.16Å; A423-L428 WeakPolarHBondContact O-CA 3.37Å; A423-L428 WeakPolarHBondContact O-CB 3.16Å; A423-L428 PolarHBondContact O-N 3.32Å; A423-G429 PolarHBondContact O-N 2.6Å; A423-F432 HydrophobicContact CB-CD2 4.09Å
424H77.3Confident81.5Confident96 Ų9649.7 Ų49.744%0.44427%0.269SS..Hα-helixtrans-63.8-44.4174.3-87.3-90.1000112.7H420 F421 Q422 M426 G427 G429H420-H424 AromaticContact CE1-CD2 2.99Å; H420-H424 PolarHBondContact CE1-CD2 3.3Å; H420-H424 AromaticContact CE1-NE2 2.93Å; H420-H424 PolarHBondContact CE1-NE2 3.19Å; H420-H424 AromaticContact ND1-CD2 3.49Å; H420-H424 PolarHBondContact ND1-CD2 3.48Å; H420-H424 AromaticContact ND1-NE2 3.88Å; H420-H424 AromaticContact NE2-CD2 3.52Å; H420-H424 AromaticContact NE2-NE2 3.21Å; H420-H424 PolarHBondContact NE2-NE2 2.95Å; H420-H424 PolarHBondContact O-CD2 2.9Å; H420-H424 PolarHBondContact O-N 3.06Å; F421-H424 PolarHBondContact O-N 3.29Å; Q422-H424 VanDerWaalsContact C-N 3.3Å; Q422-H424 PolarHBondContact O-N 3.44Å; H424-M426 PolarHBondContact O-N 2.94Å; H424-G427 PolarHBondContact O-N 2.91Å; H424-G429 WeakPolarHBondContact NE2-CA 3.4Å
425S75.7Confident82Confident100 Ų10049.2 Ų49.270%0.69926%0.264SS*.Hα-helixtrans-61.3-27.2178.374.90000113.3F421 Q422F421-S425 PolarHBondContact O-N 3.36Å; Q422-S425 PolarHBondContact O-N 3.5Å; Q422-S425 VanDerWaalsContact O-N 3.1Å; Q422-S425 PolarHBondContact O-OG 2.84Å
426M76.3Confident82.3Confident93 Ų9349.7 Ų49.746%0.45827%0.266SS..THydrogen-bonded Turntrans-93.45.4178.4-60.6179.1100.200113.5Q422 A423 H424 L428 Q464 Q468Q422-M426 WeakPolarHBondContact O-CG 3.48Å; Q422-M426 PolarHBondContact O-N 2.95Å; A423-M426 PolarHBondContact O-N 3.48Å; H424-M426 PolarHBondContact O-N 2.94Å; M426-L428 VanDerWaalsContact C-N 3.28Å; M426-L428 HydrophobicContact CB-CD1 4.48Å; M426-L428 HydrophobicContact CB-CG 4.43Å; M426-L428 PolarHBondContact O-N 3.11Å; M426-Q464 PolarHBondContact SD-OE1 3.26Å; M426-Q464 VanDerWaalsContact SD-OE1 3.37Å; M426-Q468 PolarHBondContact SD-NE2 3.38Å
427G79.1Confident82.8Confident58 Ų5855.5 Ų55.560%0.59829%0.291SS*.THydrogen-bonded Turntrans74.513.9-178.200000114.8A423 H424A423-G427 PolarHBondContact O-N 2.86Å; H424-G427 PolarHBondContact O-N 2.91Å
428L77.5Confident83.4Confident19 Ų1955.9 Ų55.910%0.09930%0.295CS..  trans-9810.1178.1-61.4176.2000113.4A423 M426 N430 K431 F432 V467 Q468A423-L428 HydrophobicContact CB-CB 4.22Å; A423-L428 CarbonylContact O-C 3.16Å; A423-L428 WeakPolarHBondContact O-CA 3.37Å; A423-L428 WeakPolarHBondContact O-CB 3.16Å; A423-L428 PolarHBondContact O-N 3.32Å; M426-L428 VanDerWaalsContact C-N 3.28Å; M426-L428 HydrophobicContact CB-CD1 4.48Å; M426-L428 HydrophobicContact CB-CG 4.43Å; M426-L428 PolarHBondContact O-N 3.11Å; L428-N430 VanDerWaalsContact C-N 3.25Å; L428-N430 PolarHBondContact O-N 3.42Å; L428-K431 HydrophobicContact CD2-CD 4.09Å; L428-K431 CarbonylContact O-C 3.57Å; L428-K431 WeakPolarHBondContact O-CA 3.28Å; L428-K431 WeakPolarHBondContact O-CB 3.5Å; L428-K431 PolarHBondContact O-N 3.44Å; L428-F432 PolarHBondContact O-N 2.88Å; L428-V467 HydrophobicContact CD1-CG1 4.41Å; L428-V467 HydrophobicContact CD2-CG1 4.29Å; L428-Q468 HydrophobicContact CD1-CG 3.69Å
429G75.8Confident84.1Confident14 Ų1453 Ų5314%0.14428%0.279CS..G310 helixtrans-56.8-36.6-175.500000113.7A423 H424 K431A423-G429 PolarHBondContact O-N 2.6Å; H424-G429 WeakPolarHBondContact NE2-CA 3.4Å; G429-K431 VanDerWaalsContact C-N 3.26Å; G429-K431 PolarHBondContact O-N 3.3Å
430N81.5Confident84.8Confident142 Ų14253.8 Ų53.876%0.75929%0.286SS*.G310 helixtrans-73-15.6175.163.3-23.6000113.8L428L428-N430 VanDerWaalsContact C-N 3.25Å; L428-N430 PolarHBondContact O-N 3.42Å
431K82.4Confident85.6Confident59 Ų5956 Ų5626%0.25730%0.297SS..G310 helixtrans-102.414.6179.8-68.6-174.1164.9-153.70113L428 G429 K433 E434 V435 V467L428-K431 HydrophobicContact CD2-CD 4.09Å; L428-K431 CarbonylContact O-C 3.57Å; L428-K431 WeakPolarHBondContact O-CA 3.28Å; L428-K431 WeakPolarHBondContact O-CB 3.5Å; L428-K431 PolarHBondContact O-N 3.44Å; G429-K431 VanDerWaalsContact C-N 3.26Å; G429-K431 PolarHBondContact O-N 3.3Å; K431-K433 PolarHBondContact O-N 2.81Å; K431-K433 VanDerWaalsContact O-N 3.1Å; K431-E434 HydrophobicContact CB-CB 4.42Å; K431-E434 WeakPolarHBondContact CD-OE2 3.43Å; K431-E434 IonicContact NZ-OE2 3.52Å; K431-E434 WeakPolarHBondContact O-CA 3.2Å; K431-E434 VanDerWaalsContact O-CB 3.31Å; K431-E434 WeakPolarHBondContact O-CB 3.3Å; K431-E434 PolarHBondContact O-N 3.16Å; K431-V435 PolarHBondContact O-N 3.4Å; K431-V467 HydrophobicContact CD-CG1 4.3Å
432F85.4Confident86.4Confident16 Ų1654.6 Ų54.67%0.0729%0.291CS..Hα-helixtrans-59.2-30.7-175.1-167-111.2000113.7Y416 L419 H420 A423 L428 E434 V435 K436Y416-F432 HydrophobicContact CE1-CE1 4.03Å; Y416-F432 HydrophobicContact CE1-CZ 4.35Å; Y416-F432 AromaticContact CE2-CE1 3.99Å; Y416-F432 HydrophobicContact CE2-CE1 3.99Å; Y416-F432 HydrophobicContact CE2-CZ 4.33Å; Y416-F432 AromaticContact CZ-CE1 3.62Å; L419-F432 HydrophobicContact CD2-CE2 4.26Å; L419-F432 HydrophobicContact CG-CE2 4.24Å; H420-F432 VanDerWaalsContact CA-CE2 3.49Å; H420-F432 HydrophobicContact CB-CD2 4.41Å; H420-F432 HydrophobicContact CB-CE2 3.78Å; H420-F432 HydrophobicContact CB-CZ 3.82Å; H420-F432 AromaticContact CD2-CD1 3.68Å; H420-F432 AromaticContact CD2-CD2 3.74Å; H420-F432 AromaticContact CD2-CE1 3.78Å; H420-F432 AromaticContact CD2-CE2 3.85Å; H420-F432 AromaticContact CD2-CG 3.65Å; H420-F432 AromaticContact CD2-CZ 3.87Å; A423-F432 HydrophobicContact CB-CD2 4.09Å; L428-F432 PolarHBondContact O-N 2.88Å; F432-E434 VanDerWaalsContact C-N 3.33Å; F432-E434 PolarHBondContact O-N 2.66Å; F432-V435 HydrophobicContact CD2-CB 4.34Å; F432-V435 WeakPolarHBondContact O-CB 3.49Å; F432-V435 PolarHBondContact O-N 2.95Å; F432-K436 HydrophobicContact CD1-CD 4.23Å; F432-K436 HydrophobicContact CD1-CG 4.29Å; F432-K436 HydrophobicContact CE1-CD 3.82Å; F432-K436 HydrophobicContact CE1-CG 3.96Å; F432-K436 HydrophobicContact CZ-CG 4.3Å; F432-K436 WeakPolarHBondContact O-CG 3.33Å; F432-K436 PolarHBondContact O-N 3.43Å
433K88.5Confident87.2Confident153 Ų15352.3 Ų52.367%0.66528%0.28SS*.Hα-helixtrans-61.7-39.3171.3-175176.2-179.2175.60112.7K431 K436 K437K431-K433 PolarHBondContact O-N 2.81Å; K431-K433 VanDerWaalsContact O-N 3.1Å; K433-K436 PolarHBondContact O-N 2.88Å; K433-K437 PolarHBondContact O-N 3.47Å
434E91.1Very high88Confident92 Ų9257.2 Ų57.243%0.4330%0.301SS..Hα-helixtrans-67-40.8174.6-63.3167-150.800110.3K431 F432 K436 K437 A438 V467K431-E434 HydrophobicContact CB-CB 4.42Å; K431-E434 WeakPolarHBondContact CD-OE2 3.43Å; K431-E434 IonicContact NZ-OE2 3.52Å; K431-E434 WeakPolarHBondContact O-CA 3.2Å; K431-E434 VanDerWaalsContact O-CB 3.31Å; K431-E434 WeakPolarHBondContact O-CB 3.3Å; K431-E434 PolarHBondContact O-N 3.16Å; F432-E434 VanDerWaalsContact C-N 3.33Å; F432-E434 PolarHBondContact O-N 2.66Å; E434-K436 PolarHBondContact O-N 2.95Å; E434-K437 PolarHBondContact O-N 3.33Å; E434-A438 WeakPolarHBondContact O-CB 3.35Å; E434-A438 PolarHBondContact O-N 3.49Å; E434-V467 HydrophobicContact CB-CG1 4.49Å; E434-V467 HydrophobicContact CB-CG2 4.29Å
435V92.2Very high88.9Confident0 Ų052.8 Ų52.80%028%0.281CS..Hα-helixtrans-59.1-43.9175.5177.50000111.5L419 K431 F432 K437 A438 Y439 V467L419-V435 HydrophobicContact CD1-CG1 4.38Å; L419-V435 HydrophobicContact CD2-CG1 3.77Å; L419-V435 HydrophobicContact CG-CG1 4.06Å; K431-V435 PolarHBondContact O-N 3.4Å; F432-V435 HydrophobicContact CD2-CB 4.34Å; F432-V435 WeakPolarHBondContact O-CB 3.49Å; F432-V435 PolarHBondContact O-N 2.95Å; V435-K437 PolarHBondContact O-N 3.14Å; V435-A438 PolarHBondContact O-N 3.42Å; V435-Y439 WeakPolarHBondContact O-CB 3.39Å; V435-Y439 PolarHBondContact O-N 3.37Å; V435-V467 HydrophobicContact CG2-CB 4.43Å; V435-V467 HydrophobicContact CG2-CG1 4.28Å; V435-V467 HydrophobicContact CG2-CG2 4.15Å
436K93.1Very high89.9Confident22 Ų2248 Ų4810%0.09625%0.248CC..Hα-helixtrans-63.9-40.3176.7-69.1-167.7-68.1-175.60113.1N403 D405 I411 Y416 F432 K433 E434 Y439 A440N403-K436 PolarHBondContact ND2-NZ 3.28Å; N403-K436 VanDerWaalsContact ND2-NZ 3.2Å; D405-K436 IonicContact OD1-NZ 3.4Å; D405-K436 WeakPolarHBondContact OD2-CE 3.16Å; D405-K436 IonicContact OD2-NZ 2.59Å; D405-K436 PolarHBondContact OD2-NZ 3.27Å; I411-K436 HydrophobicContact CD1-CB 4.4Å; I411-K436 HydrophobicContact CD1-CD 4.42Å; I411-K436 HydrophobicContact CD1-CG 3.86Å; Y416-K436 HydrophobicContact CE2-CD 3.91Å; F432-K436 HydrophobicContact CD1-CD 4.23Å; F432-K436 HydrophobicContact CD1-CG 4.29Å; F432-K436 HydrophobicContact CE1-CD 3.82Å; F432-K436 HydrophobicContact CE1-CG 3.96Å; F432-K436 HydrophobicContact CZ-CG 4.3Å; F432-K436 WeakPolarHBondContact O-CG 3.33Å; F432-K436 PolarHBondContact O-N 3.43Å; K433-K436 PolarHBondContact O-N 2.88Å; E434-K436 PolarHBondContact O-N 2.95Å; K436-Y439 WeakPolarHBondContact O-CB 3.29Å; K436-Y439 PolarHBondContact O-N 3.09Å; K436-A440 PolarHBondContact O-N 2.94Å
437K94.8Very high90.9Very high137 Ų13744.9 Ų44.960%0.59624%0.239SC*.Hα-helixtrans-64.4-46.1174-72.1-177.9173.9-168.50111.5K433 E434 V435 Y439 A440 E441K433-K437 PolarHBondContact O-N 3.47Å; E434-K437 PolarHBondContact O-N 3.33Å; V435-K437 PolarHBondContact O-N 3.14Å; K437-Y439 PolarHBondContact O-N 3.33Å; K437-A440 PolarHBondContact O-N 2.72Å; K437-E441 PolarHBondContact O-N 3.49Å; K437-E441 VanDerWaalsContact O-N 3.13Å
438A96.1Very high91.6Very high11 Ų1143.8 Ų43.89%0.09122%0.219CC..Hα-helixtrans-62.2-30.8176.300000111.8E434 V435 E441 A442 A463 M466 V467E434-A438 WeakPolarHBondContact O-CB 3.35Å; E434-A438 PolarHBondContact O-N 3.49Å; V435-A438 PolarHBondContact O-N 3.42Å; A438-E441 PolarHBondContact O-N 3.08Å; A438-A442 WeakPolarHBondContact O-CB 3.45Å; A438-A442 PolarHBondContact O-N 3.02Å; A438-A463 HydrophobicContact CB-CB 4.05Å; A438-M466 HydrophobicContact CB-CB 4.43Å; A438-V467 HydrophobicContact CB-CG2 3.63Å
439Y96.8Very high92.5Very high0 Ų042.9 Ų42.90%022%0.215CC..Hα-helixtrans-64.5-44.7175.1-167.9-81.5000112.3N409 I411 Q415 L419 V435 K436 K437 E441 A442 N443 K451 S456 V459 A463N409-Y439 WeakPolarHBondContact O-CD1 3.34Å; N409-Y439 WeakPolarHBondContact O-CE1 3.37Å; I411-Y439 HydrophobicContact CB-CE1 4.29Å; I411-Y439 HydrophobicContact CD1-CD1 4.13Å; I411-Y439 HydrophobicContact CD1-CD2 4.28Å; I411-Y439 HydrophobicContact CD1-CG 3.96Å; I411-Y439 HydrophobicContact CG1-CD1 3.39Å; I411-Y439 HydrophobicContact CG1-CD2 3.98Å; I411-Y439 HydrophobicContact CG1-CE1 3.42Å; I411-Y439 VanDerWaalsContact CG1-CE1 3.42Å; I411-Y439 HydrophobicContact CG1-CE2 4.06Å; I411-Y439 HydrophobicContact CG1-CG 3.66Å; Q415-Y439 HydrophobicContact CG-CE2 4.5Å; L419-Y439 HydrophobicContact CD2-CD2 4.14Å; V435-Y439 WeakPolarHBondContact O-CB 3.39Å; V435-Y439 PolarHBondContact O-N 3.37Å; K436-Y439 WeakPolarHBondContact O-CB 3.29Å; K436-Y439 PolarHBondContact O-N 3.09Å; K437-Y439 PolarHBondContact O-N 3.33Å; Y439-E441 VanDerWaalsContact C-N 3.33Å; Y439-E441 PolarHBondContact O-N 3.21Å; Y439-A442 PolarHBondContact O-N 3.28Å; Y439-N443 PolarHBondContact O-N 3.44Å; Y439-K451 HydrophobicContact CE1-CD 3.65Å; Y439-S456 WeakPolarHBondContact CE2-O 3.26Å; Y439-S456 WeakPolarHBondContact OH-CA 3.37Å; Y439-S456 PolarHBondContact OH-O 3.36Å; Y439-V459 HydrophobicContact CD1-CG1 3.76Å; Y439-V459 HydrophobicContact CD2-CB 4.4Å; Y439-V459 HydrophobicContact CD2-CG1 3.79Å; Y439-V459 HydrophobicContact CE1-CB 4.37Å; Y439-V459 HydrophobicContact CE1-CG1 3.72Å; Y439-V459 HydrophobicContact CE2-CB 3.87Å; Y439-V459 HydrophobicContact CE2-CG1 3.69Å; Y439-V459 HydrophobicContact CG-CG1 3.82Å; Y439-V459 WeakPolarHBondContact O-CG1 3.33Å; Y439-A463 HydrophobicContact CD2-CB 4.3Å
440A96.6Very high93.5Very high18 Ų1842.3 Ų42.315%0.14921%0.208CC..Hα-helixtrans-62.1-41173.700000111.8K436 K437 N443 K444K436-A440 PolarHBondContact O-N 2.94Å; K437-A440 PolarHBondContact O-N 2.72Å; A440-N443 WeakPolarHBondContact O-CB 3.49Å; A440-N443 PolarHBondContact O-N 3.06Å; A440-K444 WeakPolarHBondContact O-CG 3.34Å; A440-K444 PolarHBondContact O-N 2.82Å
441E97.6Very high94.2Very high62 Ų6235.5 Ų35.529%0.2917%0.172SC..Hα-helixtrans-70.1-39.5177.8-68.1-5412500113K437 A438 Y439 N443 K444 L445 M466 R473K437-E441 PolarHBondContact O-N 3.49Å; K437-E441 VanDerWaalsContact O-N 3.13Å; A438-E441 PolarHBondContact O-N 3.08Å; Y439-E441 VanDerWaalsContact C-N 3.33Å; Y439-E441 PolarHBondContact O-N 3.21Å; E441-N443 VanDerWaalsContact C-N 3.32Å; E441-N443 PolarHBondContact O-N 2.57Å; E441-K444 PolarHBondContact O-N 3.16Å; E441-K444 IonicContact OE1-NZ 3.67Å; E441-K444 PolarHBondContact OE1-NZ 3.46Å; E441-L445 PolarHBondContact O-N 3.11Å; E441-M466 HydrophobicContact CB-CE 4.24Å; E441-R473 HydrophobicContact CB-CB 4.34Å; E441-R473 WeakPolarHBondContact OE2-CD 3.47Å
442A97.6Very high94.6Very high0 Ų033.1 Ų33.10%016%0.162CC..Hα-helixtrans-61-39.8172.300000111.6A438 Y439 K444 L445 L446 V459 L462 A463 M466A438-A442 WeakPolarHBondContact O-CB 3.45Å; A438-A442 PolarHBondContact O-N 3.02Å; Y439-A442 PolarHBondContact O-N 3.28Å; A442-K444 VanDerWaalsContact C-N 3.34Å; A442-K444 PolarHBondContact O-N 2.96Å; A442-L445 WeakPolarHBondContact O-CB 3.13Å; A442-L445 PolarHBondContact O-N 2.88Å; A442-L446 WeakPolarHBondContact O-CB 3.1Å; A442-L446 VanDerWaalsContact O-CG 3.32Å; A442-L446 WeakPolarHBondContact O-CG 3.07Å; A442-L446 PolarHBondContact O-N 2.86Å; A442-V459 HydrophobicContact CB-CG1 3.93Å; A442-L462 HydrophobicContact CB-CB 4.02Å; A442-L462 HydrophobicContact CB-CD2 3.86Å; A442-L462 HydrophobicContact CB-CG 3.83Å; A442-A463 HydrophobicContact CB-CB 4.33Å; A442-M466 HydrophobicContact CB-SD 4.14Å
443N97.3Very high94.7Very high7 Ų734 Ų344%0.03717%0.169CC..Hα-helixtrans-59-46.6174-179.947.3000111.2Y439 A440 E441 L446 G447 D448 L449 K451 V459Y439-N443 PolarHBondContact O-N 3.44Å; A440-N443 WeakPolarHBondContact O-CB 3.49Å; A440-N443 PolarHBondContact O-N 3.06Å; E441-N443 VanDerWaalsContact C-N 3.32Å; E441-N443 PolarHBondContact O-N 2.57Å; N443-L446 PolarHBondContact O-N 2.85Å; N443-G447 PolarHBondContact O-N 2.89Å; N443-D448 PolarHBondContact ND2-OD1 3.33Å; N443-D448 WeakPolarHBondContact O-CA 3.44Å; N443-D448 PolarHBondContact O-N 3.21Å; N443-L449 PolarHBondContact OD1-N 2.68Å; N443-L449 PolarHBondContact OD1-O 3.04Å; N443-K451 HydrophobicContact CB-CD 4.14Å; N443-K451 PolarHBondContact ND2-NZ 3.31Å; N443-K451 VanDerWaalsContact ND2-NZ 3.15Å; N443-K451 PolarHBondContact OD1-NZ 3.21Å; N443-V459 HydrophobicContact CB-CG1 4.16Å
444K95.8Very high94.8Very high102 Ų10227.3 Ų27.344%0.44314%0.141SC..Hα-helixtrans-67.3-38179-58.7170.1-175.3164.70112.3A440 E441 A442 L446 G447A440-K444 WeakPolarHBondContact O-CG 3.34Å; A440-K444 PolarHBondContact O-N 2.82Å; E441-K444 PolarHBondContact O-N 3.16Å; E441-K444 IonicContact OE1-NZ 3.67Å; E441-K444 PolarHBondContact OE1-NZ 3.46Å; A442-K444 VanDerWaalsContact C-N 3.34Å; A442-K444 PolarHBondContact O-N 2.96Å; K444-L446 VanDerWaalsContact C-N 3.25Å; K444-L446 PolarHBondContact O-N 2.81Å; K444-G447 PolarHBondContact O-N 3.14Å; K444-G447 VanDerWaalsContact O-N 3.11Å
445L96.6Very high94.9Very high3 Ų323 Ų232%0.01612%0.121CC..Hα-helixtrans-56.5-41.2173-84.6170.4000112E441 A442 G447 L462 M466 R473 V476 E477 P505E441-L445 PolarHBondContact O-N 3.11Å; A442-L445 WeakPolarHBondContact O-CB 3.13Å; A442-L445 PolarHBondContact O-N 2.88Å; L445-G447 PolarHBondContact O-N 3.25Å; L445-L462 HydrophobicContact CB-CD2 4.37Å; L445-L462 HydrophobicContact CD1-CD2 4.29Å; L445-M466 HydrophobicContact CD1-CE 3.97Å; L445-M466 HydrophobicContact CD1-SD 3.75Å; L445-R473 HydrophobicContact CD1-CB 4.39Å; L445-R473 HydrophobicContact CD1-CG 4.32Å; L445-R473 HydrophobicContact CD2-CG 3.72Å; L445-R473 HydrophobicContact CG-CB 4.37Å; L445-R473 HydrophobicContact CG-CG 3.8Å; L445-V476 HydrophobicContact CD1-CB 4.11Å; L445-V476 HydrophobicContact CD1-CG1 3.88Å; L445-V476 HydrophobicContact CD2-CG1 4.28Å; L445-E477 HydrophobicContact CD2-CG 3.28Å; L445-P505 WeakPolarHBondContact O-CG 3.27Å
446L96.8Very high94.9Very high0 Ų023 Ų230%012%0.121CC..THydrogen-bonded Turntrans-83.55.8-179.5-63.1172.6000113.3A442 N443 K444 L449 I458 V459 L462 V489 F492 L493 F508A442-L446 WeakPolarHBondContact O-CB 3.1Å; A442-L446 VanDerWaalsContact O-CG 3.32Å; A442-L446 WeakPolarHBondContact O-CG 3.07Å; A442-L446 PolarHBondContact O-N 2.86Å; N443-L446 PolarHBondContact O-N 2.85Å; K444-L446 VanDerWaalsContact C-N 3.25Å; K444-L446 PolarHBondContact O-N 2.81Å; L446-L449 HydrophobicContact CB-CD1 3.77Å; L446-L449 HydrophobicContact CB-CG 4.06Å; L446-L449 HydrophobicContact CD1-CD1 4.31Å; L446-L449 WeakPolarHBondContact O-CD2 3.48Å; L446-I458 HydrophobicContact CD1-CG2 4.02Å; L446-V459 HydrophobicContact CD1-CG2 3.95Å; L446-L462 HydrophobicContact CD1-CD2 3.85Å; L446-L462 HydrophobicContact CD2-CD2 4.04Å; L446-L462 HydrophobicContact CG-CD2 3.79Å; L446-V489 HydrophobicContact CD2-CG1 4.11Å; L446-F492 HydrophobicContact CB-CE1 4.22Å; L446-F492 HydrophobicContact CD2-CD1 4.02Å; L446-F492 HydrophobicContact CD2-CE1 3.93Å; L446-L493 HydrophobicContact CD2-CD2 4.5Å; L446-F508 HydrophobicContact CD2-CE1 4.15Å
447G95.4Very high94.8Very high27 Ų2726 Ų2628%0.27813%0.134SC..THydrogen-bonded Turntrans9522.1172.800000115.1K262 N443 K444 L445K262-G447 PolarHBondContact NZ-O 3.48Å; N443-G447 PolarHBondContact O-N 2.89Å; K444-G447 PolarHBondContact O-N 3.14Å; K444-G447 VanDerWaalsContact O-N 3.11Å; L445-G447 PolarHBondContact O-N 3.25Å
448D95.8Very high94.8Very high35 Ų3519.7 Ų19.719%0.18711%0.107CC..SBendtrans60.481.1-176.2-168.325.3000112.3R260 K262 Y263 N443R260-D448 IonicContact NH2-OD1 2.81Å; R260-D448 IonicContact NH2-OD2 3.58Å; K262-D448 HydrophobicContact CD-CB 4.23Å; K262-D448 PolarHBondContact NZ-O 3.04Å; Y263-D448 WeakPolarHBondContact CE2-O 3.35Å; Y263-D448 PolarHBondContact OH-O 3.06Å; N443-D448 PolarHBondContact ND2-OD1 3.33Å; N443-D448 WeakPolarHBondContact O-CA 3.44Å; N443-D448 PolarHBondContact O-N 3.21Å
449L95.6Very high94.8Very high1 Ų119.1 Ų19.11%0.00510%0.103CC..  trans-90.2154.3-173.2-58.6-175.8000112.4L225 N443 L446 K451 V459 F492 P500L225-L449 HydrophobicContact CD2-CD2 4.41Å; N443-L449 PolarHBondContact OD1-N 2.68Å; N443-L449 PolarHBondContact OD1-O 3.04Å; L446-L449 HydrophobicContact CB-CD1 3.77Å; L446-L449 HydrophobicContact CB-CG 4.06Å; L446-L449 HydrophobicContact CD1-CD1 4.31Å; L446-L449 WeakPolarHBondContact O-CD2 3.48Å; L449-K451 HydrophobicContact CB-CG 4.45Å; L449-K451 PolarHBondContact O-NZ 3.35Å; L449-V459 HydrophobicContact CD1-CG2 4.37Å; L449-F492 HydrophobicContact CD1-CE1 4.07Å; L449-F492 HydrophobicContact CD1-CE2 4.01Å; L449-F492 HydrophobicContact CD1-CZ 3.67Å; L449-F492 HydrophobicContact CD2-CE2 4.32Å; L449-F492 HydrophobicContact CD2-CZ 3.79Å; L449-F492 HydrophobicContact CG-CZ 4.36Å; L449-P500 HydrophobicContact CD2-CB 3.64Å; L449-P500 HydrophobicContact CD2-CG 4.39Å
450I96.9Very high94.7Very high1 Ų119.1 Ų19.11%0.00510%0.103CC..  trans-66.6130.5152.6-65.2151.5000107.4S224 L225 N226 S250 T252 Y263 M288 V452 S455S224-I450 WeakPolarHBondContact O-CG2 3.33Å; L225-I450 WeakPolarHBondContact O-CD1 3.5Å; N226-I450 HydrophobicContact CB-CD1 3.68Å; N226-I450 VanDerWaalsContact ND2-CD1 3.27Å; N226-I450 WeakPolarHBondContact ND2-CD1 3.36Å; S250-I450 VanDerWaalsContact CB-CG2 3.47Å; T252-I450 HydrophobicContact CG2-CB 4.41Å; T252-I450 HydrophobicContact CG2-CG1 3.59Å; Y263-I450 HydrophobicContact CD1-CG1 4.48Å; Y263-I450 HydrophobicContact CE1-CD1 3.79Å; Y263-I450 HydrophobicContact CE1-CG1 3.77Å; Y263-I450 PolarHBondContact OH-N 3.43Å; M288-I450 HydrophobicContact CE-CG2 3.94Å; I450-V452 HydrophobicContact CG2-CG1 4.34Å; I450-S455 WeakPolarHBondContact O-CB 3.35Å; I450-S455 PolarHBondContact O-OG 3Å
451K94.9Very high94.6Very high0 Ų019.3 Ų19.30%010%0.101CC..  trans-11893.3-170.8-68.8169.9-64.3-690110.2M288 E410 P412 Y439 N443 L449 S455 V459M288-K451 VanDerWaalsContact CE-O 3.22Å; M288-K451 WeakPolarHBondContact CE-O 3.38Å; M288-K451 WeakPolarHBondContact CG-O 3.4Å; E410-K451 WeakPolarHBondContact O-CE 3.22Å; E410-K451 WeakPolarHBondContact OE2-CE 3.38Å; E410-K451 IonicContact OE2-NZ 2.62Å; E410-K451 PolarHBondContact OE2-NZ 2.76Å; P412-K451 HydrophobicContact CG-CB 4.5Å; P412-K451 WeakPolarHBondContact CG-O 3.27Å; Y439-K451 HydrophobicContact CE1-CD 3.65Å; N443-K451 HydrophobicContact CB-CD 4.14Å; N443-K451 PolarHBondContact ND2-NZ 3.31Å; N443-K451 VanDerWaalsContact ND2-NZ 3.15Å; N443-K451 PolarHBondContact OD1-NZ 3.21Å; L449-K451 HydrophobicContact CB-CG 4.45Å; L449-K451 PolarHBondContact O-NZ 3.35Å; K451-S455 WeakPolarHBondContact CA-OG 3.3Å; K451-V459 HydrophobicContact CD-CG1 4.38Å; K451-V459 HydrophobicContact CD-CG2 4.13Å; K451-V459 HydrophobicContact CG-CG2 4.04Å
452V92.3Very high94.5Very high8 Ų816.4 Ų16.45%0.0489%0.087CC..  trans-146158.3173.9620000107.2F222 S224 M288 I450 P454 S455 S456F222-V452 HydrophobicContact CD2-CG1 4.04Å; F222-V452 HydrophobicContact CD2-CG2 4.32Å; F222-V452 HydrophobicContact CE2-CB 4.36Å; F222-V452 HydrophobicContact CE2-CG1 3.71Å; F222-V452 HydrophobicContact CE2-CG2 3.68Å; F222-V452 HydrophobicContact CZ-CG2 4.4Å; S224-V452 VanDerWaalsContact CA-CG1 3.41Å; M288-V452 HydrophobicContact CB-CB 4.49Å; M288-V452 HydrophobicContact CB-CG2 4.2Å; M288-V452 HydrophobicContact CE-CB 4.49Å; M288-V452 HydrophobicContact CG-CB 3.94Å; M288-V452 HydrophobicContact CG-CG2 4.2Å; M288-V452 HydrophobicContact SD-CB 4.29Å; I450-V452 HydrophobicContact CG2-CG1 4.34Å; V452-P454 CarbonylContact O-C 3.25Å; V452-P454 VanDerWaalsContact O-N 3.15Å; V452-S455 PolarHBondContact N-OG 3.26Å; V452-S455 PolarHBondContact O-N 2.99Å; V452-S455 PolarHBondContact O-OG 3.44Å; V452-S456 PolarHBondContact O-N 3.49Å
453T87.8Confident94.4Very high34 Ų3416.4 Ų16.421%0.2099%0.087CC..THydrogen-bonded Turntrans-52.3124.3-173.3-59.30000111.8R189 Y196 S456R189-T453 WeakPolarHBondContact CD-O 3.27Å; Y196-T453 HydrophobicContact CD1-CG2 4.4Å; Y196-T453 HydrophobicContact CE1-CG2 3.98Å; T453-S456 PolarHBondContact N-OG 3.04Å
454P89.3Confident94.2Very high14 Ų1416.7 Ų16.79%0.0919%0.089CC..THydrogen-bonded Turncis-98.6-2.87.637.5-30.8000115.7V452 S456 K457 I458 V497V452-P454 CarbonylContact O-C 3.25Å; V452-P454 VanDerWaalsContact O-N 3.15Å; P454-S456 VanDerWaalsContact C-N 3.29Å; P454-S456 PolarHBondContact O-N 2.69Å; P454-K457 WeakPolarHBondContact O-CB 3.23Å; P454-K457 PolarHBondContact O-N 3.1Å; P454-I458 WeakPolarHBondContact O-CG1 3.24Å; P454-I458 PolarHBondContact O-N 2.78Å; P454-I458 VanDerWaalsContact O-N 3.07Å; P454-V497 HydrophobicContact CG-CG1 4.07Å; P454-V497 HydrophobicContact CG-CG2 4.4Å
455S93.2Very high94.1Very high0 Ų013.1 Ų13.10%07%0.073CC..Hα-helixtrans-61.4-33.8-178.865.60000113.2S224 I450 K451 V452 K457 I458 V459S224-S455 PolarHBondContact O-OG 3.41Å; I450-S455 WeakPolarHBondContact O-CB 3.35Å; I450-S455 PolarHBondContact O-OG 3Å; K451-S455 WeakPolarHBondContact CA-OG 3.3Å; V452-S455 PolarHBondContact N-OG 3.26Å; V452-S455 PolarHBondContact O-N 2.99Å; V452-S455 PolarHBondContact O-OG 3.44Å; S455-K457 VanDerWaalsContact C-N 3.33Å; S455-K457 PolarHBondContact O-N 2.99Å; S455-I458 WeakPolarHBondContact O-CB 3.23Å; S455-I458 PolarHBondContact O-N 3.32Å; S455-V459 WeakPolarHBondContact O-CG2 3.23Å; S455-V459 PolarHBondContact O-N 3.31Å
456S92.9Very high94.1Very high1 Ų113.1 Ų13.11%0.0077%0.073CC..Hα-helixtrans-62.8-37.1172.659.10000113Q415 Y439 V452 T453 P454 G460Q415-S456 PolarHBondContact NE2-O 3.43Å; Y439-S456 WeakPolarHBondContact CE2-O 3.26Å; Y439-S456 WeakPolarHBondContact OH-CA 3.37Å; Y439-S456 PolarHBondContact OH-O 3.36Å; V452-S456 PolarHBondContact O-N 3.49Å; T453-S456 PolarHBondContact N-OG 3.04Å; P454-S456 VanDerWaalsContact C-N 3.29Å; P454-S456 PolarHBondContact O-N 2.69Å; S456-G460 PolarHBondContact O-N 2.93Å
457K90.7Very high93.9Very high85 Ų8513.7 Ų13.737%0.378%0.077SC..Hα-helixtrans-67.1-42.3172.9171.4172.7169.648.60111.2P454 S455 V459 G460 D461P454-K457 WeakPolarHBondContact O-CB 3.23Å; P454-K457 PolarHBondContact O-N 3.1Å; S455-K457 VanDerWaalsContact C-N 3.33Å; S455-K457 PolarHBondContact O-N 2.99Å; K457-V459 VanDerWaalsContact C-N 3.34Å; K457-V459 PolarHBondContact O-N 3.21Å; K457-G460 CarbonylContact O-C 3.49Å; K457-G460 WeakPolarHBondContact O-CA 3.37Å; K457-G460 PolarHBondContact O-N 3.43Å; K457-G460 VanDerWaalsContact O-N 3.1Å; K457-D461 WeakPolarHBondContact CE-OD2 3.15Å; K457-D461 IonicContact NZ-OD1 3.59Å; K457-D461 PolarHBondContact NZ-OD1 3.34Å; K457-D461 IonicContact NZ-OD2 2.88Å; K457-D461 PolarHBondContact NZ-OD2 3.1Å; K457-D461 VanDerWaalsContact O-CG 3.28Å; K457-D461 PolarHBondContact O-N 2.76Å
458I94.3Very high93.7Very high4 Ų416.1 Ų16.12%0.0218%0.081CC..Hα-helixtrans-58.5-47.1178.7-67.4157.4000110.8L446 P454 S455 G460 D461 L462 V489 F492 V497L446-I458 HydrophobicContact CD1-CG2 4.02Å; P454-I458 WeakPolarHBondContact O-CG1 3.24Å; P454-I458 PolarHBondContact O-N 2.78Å; P454-I458 VanDerWaalsContact O-N 3.07Å; S455-I458 WeakPolarHBondContact O-CB 3.23Å; S455-I458 PolarHBondContact O-N 3.32Å; I458-G460 VanDerWaalsContact C-N 3.33Å; I458-G460 PolarHBondContact O-N 3.04Å; I458-D461 PolarHBondContact O-N 3.41Å; I458-L462 PolarHBondContact O-N 3.09Å; I458-L462 VanDerWaalsContact O-N 3.16Å; I458-V489 HydrophobicContact CG2-CG2 4.15Å; I458-F492 HydrophobicContact CD1-CB 3.77Å; I458-F492 HydrophobicContact CD1-CD2 4.46Å; I458-F492 HydrophobicContact CD1-CG 4.34Å; I458-F492 HydrophobicContact CG1-CB 4.39Å; I458-F492 HydrophobicContact CG2-CB 3.92Å; I458-F492 HydrophobicContact CG2-CD1 4.35Å; I458-F492 HydrophobicContact CG2-CG 4.19Å; I458-V497 HydrophobicContact CD1-CG2 3.93Å
459V96.8Very high93.6Very high0 Ų018.4 Ų18.40%09%0.093CC..Hα-helixtrans-63.1-41.1175179.80000110.8Y439 A442 N443 L446 L449 K451 S455 K457 L462 A463Y439-V459 HydrophobicContact CD1-CG1 3.76Å; Y439-V459 HydrophobicContact CD2-CB 4.4Å; Y439-V459 HydrophobicContact CD2-CG1 3.79Å; Y439-V459 HydrophobicContact CE1-CB 4.37Å; Y439-V459 HydrophobicContact CE1-CG1 3.72Å; Y439-V459 HydrophobicContact CE2-CB 3.87Å; Y439-V459 HydrophobicContact CE2-CG1 3.69Å; Y439-V459 HydrophobicContact CG-CG1 3.82Å; Y439-V459 WeakPolarHBondContact O-CG1 3.33Å; A442-V459 HydrophobicContact CB-CG1 3.93Å; N443-V459 HydrophobicContact CB-CG1 4.16Å; L446-V459 HydrophobicContact CD1-CG2 3.95Å; L449-V459 HydrophobicContact CD1-CG2 4.37Å; K451-V459 HydrophobicContact CD-CG1 4.38Å; K451-V459 HydrophobicContact CD-CG2 4.13Å; K451-V459 HydrophobicContact CG-CG2 4.04Å; S455-V459 WeakPolarHBondContact O-CG2 3.23Å; S455-V459 PolarHBondContact O-N 3.31Å; K457-V459 VanDerWaalsContact C-N 3.34Å; K457-V459 PolarHBondContact O-N 3.21Å; V459-L462 PolarHBondContact O-N 3.17Å; V459-A463 WeakPolarHBondContact O-CB 3.23Å; V459-A463 PolarHBondContact O-N 3.43Å
460G94.6Very high93.5Very high0 Ų024 Ų240%012%0.123CC..Hα-helixtrans-62.1-44.7177.200000114.4S456 K457 I458 L462 A463 Q464S456-G460 PolarHBondContact O-N 2.93Å; K457-G460 CarbonylContact O-C 3.49Å; K457-G460 WeakPolarHBondContact O-CA 3.37Å; K457-G460 PolarHBondContact O-N 3.43Å; K457-G460 VanDerWaalsContact O-N 3.1Å; I458-G460 VanDerWaalsContact C-N 3.33Å; I458-G460 PolarHBondContact O-N 3.04Å; G460-L462 VanDerWaalsContact C-N 3.34Å; G460-A463 WeakPolarHBondContact O-CB 3.08Å; G460-A463 PolarHBondContact O-N 2.86Å; G460-Q464 WeakPolarHBondContact O-CG 3.29Å; G460-Q464 PolarHBondContact O-N 3.21Å
461D93.7Very high93.5Very high22 Ų2225 Ų2512%0.11813%0.128CC..Hα-helixtrans-63.9-41.9178.1-67.8-15.9000110.3K457 I458 Q464 F465 P486 S488K457-D461 WeakPolarHBondContact CE-OD2 3.15Å; K457-D461 IonicContact NZ-OD1 3.59Å; K457-D461 PolarHBondContact NZ-OD1 3.34Å; K457-D461 IonicContact NZ-OD2 2.88Å; K457-D461 PolarHBondContact NZ-OD2 3.1Å; K457-D461 VanDerWaalsContact O-CG 3.28Å; K457-D461 PolarHBondContact O-N 2.76Å; I458-D461 PolarHBondContact O-N 3.41Å; D461-Q464 PolarHBondContact O-N 3.19Å; D461-F465 WeakPolarHBondContact O-CB 3.34Å; D461-F465 PolarHBondContact O-N 2.87Å; D461-P486 HydrophobicContact CB-CB 4.02Å; D461-P486 HydrophobicContact CB-CG 4.24Å; D461-S488 WeakPolarHBondContact CB-OG 3.29Å; D461-S488 WeakPolarHBondContact OD2-CB 3.39Å; D461-S488 PolarHBondContact OD2-OG 3.31Å
462L96.3Very high93.6Very high0 Ų028.7 Ų28.70%015%0.151CC..Hα-helixtrans-64-42.6174.5-176.655.7000111.8A442 L445 L446 I458 V459 G460 Q464 F465 M466 F485 V489A442-L462 HydrophobicContact CB-CB 4.02Å; A442-L462 HydrophobicContact CB-CD2 3.86Å; A442-L462 HydrophobicContact CB-CG 3.83Å; L445-L462 HydrophobicContact CB-CD2 4.37Å; L445-L462 HydrophobicContact CD1-CD2 4.29Å; L446-L462 HydrophobicContact CD1-CD2 3.85Å; L446-L462 HydrophobicContact CD2-CD2 4.04Å; L446-L462 HydrophobicContact CG-CD2 3.79Å; I458-L462 PolarHBondContact O-N 3.09Å; I458-L462 VanDerWaalsContact O-N 3.16Å; V459-L462 PolarHBondContact O-N 3.17Å; G460-L462 VanDerWaalsContact C-N 3.34Å; L462-Q464 PolarHBondContact O-N 3.16Å; L462-F465 HydrophobicContact CD1-CD1 4.28Å; L462-F465 WeakPolarHBondContact O-CB 3.29Å; L462-F465 PolarHBondContact O-N 3.29Å; L462-M466 HydrophobicContact CD1-CG 4.39Å; L462-M466 HydrophobicContact CG-SD 4.18Å; L462-M466 VanDerWaalsContact O-CG 3.25Å; L462-M466 WeakPolarHBondContact O-CG 3.26Å; L462-M466 PolarHBondContact O-N 3.04Å; L462-F485 HydrophobicContact CD1-CD1 3.88Å; L462-F485 HydrophobicContact CD1-CE1 3.99Å; L462-V489 HydrophobicContact CB-CG2 3.82Å
463A95.9Very high93.7Very high0 Ų032 Ų320%016%0.162CC..Hα-helixtrans-61.5-44.917800000112.3A438 Y439 A442 V459 G460 M466 V467A438-A463 HydrophobicContact CB-CB 4.05Å; Y439-A463 HydrophobicContact CD2-CB 4.3Å; A442-A463 HydrophobicContact CB-CB 4.33Å; V459-A463 WeakPolarHBondContact O-CB 3.23Å; V459-A463 PolarHBondContact O-N 3.43Å; G460-A463 WeakPolarHBondContact O-CB 3.08Å; G460-A463 PolarHBondContact O-N 2.86Å; A463-M466 PolarHBondContact O-N 3.1Å; A463-V467 WeakPolarHBondContact O-CG2 3.37Å; A463-V467 PolarHBondContact O-N 3.23Å
464Q92.3Very high94.2Very high13 Ų1333.4 Ų33.46%0.06118%0.177CC..Hα-helixtrans-63.7-43.3175.4-71.6177.615.800111.3L419 M426 G460 D461 L462 M466 V467 Q468L419-Q464 HydrophobicContact CD1-CG 4.14Å; M426-Q464 PolarHBondContact SD-OE1 3.26Å; M426-Q464 VanDerWaalsContact SD-OE1 3.37Å; G460-Q464 WeakPolarHBondContact O-CG 3.29Å; G460-Q464 PolarHBondContact O-N 3.21Å; D461-Q464 PolarHBondContact O-N 3.19Å; L462-Q464 PolarHBondContact O-N 3.16Å; Q464-M466 VanDerWaalsContact C-N 3.32Å; Q464-M466 PolarHBondContact O-N 3.14Å; Q464-V467 PolarHBondContact O-N 3.25Å; Q464-Q468 WeakPolarHBondContact O-CB 3.43Å; Q464-Q468 VanDerWaalsContact O-CG 3.24Å; Q464-Q468 WeakPolarHBondContact O-CG 3.36Å; Q464-Q468 PolarHBondContact O-N 2.94Å
465F94.3Very high94.5Very high27 Ų2736.2 Ų36.212%0.11819%0.189CC..Hα-helixtrans-57.4-45.4175.3172.7-94000111.7D461 L462 Q468 N469 L471 L483 S484 F485 P486D461-F465 WeakPolarHBondContact O-CB 3.34Å; D461-F465 PolarHBondContact O-N 2.87Å; L462-F465 HydrophobicContact CD1-CD1 4.28Å; L462-F465 WeakPolarHBondContact O-CB 3.29Å; L462-F465 PolarHBondContact O-N 3.29Å; F465-Q468 PolarHBondContact O-N 2.91Å; F465-N469 WeakPolarHBondContact CD2-ND2 3.29Å; F465-N469 WeakPolarHBondContact CE2-ND2 3.26Å; F465-N469 WeakPolarHBondContact O-CB 3.45Å; F465-N469 PolarHBondContact O-N 3.26Å; F465-N469 VanDerWaalsContact O-N 3.13Å; F465-N469 PolarHBondContact O-ND2 3Å; F465-L471 HydrophobicContact CD1-CD1 4.42Å; F465-L471 HydrophobicContact CE1-CD1 3.72Å; F465-L471 HydrophobicContact CZ-CD1 4.26Å; F465-L483 HydrophobicContact CE1-CD1 4.42Å; F465-L483 HydrophobicContact CZ-CB 4.28Å; F465-L483 HydrophobicContact CZ-CD2 4.36Å; F465-S484 VanDerWaalsContact CE2-O 3.24Å; F465-S484 WeakPolarHBondContact CE2-O 3.31Å; F465-F485 HydrophobicContact CE1-CD1 4.47Å; F465-F485 HydrophobicContact CE1-CE1 4.47Å; F465-P486 HydrophobicContact CB-CG 3.88Å; F465-P486 HydrophobicContact CD2-CG 4.41Å; F465-P486 HydrophobicContact CG-CG 4.26Å
466M95.6Very high94.7Very high4 Ų436.2 Ų36.22%0.0219%0.189CC..Hα-helixtrans-60.1-47.9176.7-71.617270.600111.6A438 E441 A442 L445 L462 A463 Q464 N469 N470 L471 R473 V476A438-M466 HydrophobicContact CB-CB 4.43Å; E441-M466 HydrophobicContact CB-CE 4.24Å; A442-M466 HydrophobicContact CB-SD 4.14Å; L445-M466 HydrophobicContact CD1-CE 3.97Å; L445-M466 HydrophobicContact CD1-SD 3.75Å; L462-M466 HydrophobicContact CD1-CG 4.39Å; L462-M466 HydrophobicContact CG-SD 4.18Å; L462-M466 VanDerWaalsContact O-CG 3.25Å; L462-M466 WeakPolarHBondContact O-CG 3.26Å; L462-M466 PolarHBondContact O-N 3.04Å; A463-M466 PolarHBondContact O-N 3.1Å; Q464-M466 VanDerWaalsContact C-N 3.32Å; Q464-M466 PolarHBondContact O-N 3.14Å; M466-N469 PolarHBondContact O-N 3.34Å; M466-N470 PolarHBondContact O-N 2.72Å; M466-L471 PolarHBondContact O-N 3.09Å; M466-R473 HydrophobicContact CE-CB 4.43Å; M466-V476 HydrophobicContact CE-CG2 4.38Å; M466-V476 HydrophobicContact CG-CG2 3.96Å
467V93.8Very high94.8Very high12 Ų1239.4 Ų39.47%0.07320%0.204CC..Hα-helixtrans-66.3-40.5-179.6173.40000112.2L428 K431 E434 V435 A438 A463 Q464 N469 N470L428-V467 HydrophobicContact CD1-CG1 4.41Å; L428-V467 HydrophobicContact CD2-CG1 4.29Å; K431-V467 HydrophobicContact CD-CG1 4.3Å; E434-V467 HydrophobicContact CB-CG1 4.49Å; E434-V467 HydrophobicContact CB-CG2 4.29Å; V435-V467 HydrophobicContact CG2-CB 4.43Å; V435-V467 HydrophobicContact CG2-CG1 4.28Å; V435-V467 HydrophobicContact CG2-CG2 4.15Å; A438-V467 HydrophobicContact CB-CG2 3.63Å; A463-V467 WeakPolarHBondContact O-CG2 3.37Å; A463-V467 PolarHBondContact O-N 3.23Å; Q464-V467 PolarHBondContact O-N 3.25Å; V467-N469 VanDerWaalsContact C-N 3.29Å; V467-N469 PolarHBondContact O-N 3.03Å; V467-N470 PolarHBondContact O-N 2.74Å
468Q91.6Very high95Very high78 Ų7842.1 Ų42.136%0.36422%0.218SC..Hα-helixtrans-63.4-37.6179.2-75.5171.113.700112.5M426 L428 Q464 F465M426-Q468 PolarHBondContact SD-NE2 3.38Å; L428-Q468 HydrophobicContact CD1-CG 3.69Å; Q464-Q468 WeakPolarHBondContact O-CB 3.43Å; Q464-Q468 VanDerWaalsContact O-CG 3.24Å; Q464-Q468 WeakPolarHBondContact O-CG 3.36Å; Q464-Q468 PolarHBondContact O-N 2.94Å; F465-Q468 PolarHBondContact O-N 2.91Å
469N92.9Very high95.1Very high82 Ų8246.5 Ų46.544%0.43923%0.234SC..THydrogen-bonded Turntrans-94.85.1-178-65.2-80000112.7F465 M466 V467 L471F465-N469 WeakPolarHBondContact CD2-ND2 3.29Å; F465-N469 WeakPolarHBondContact CE2-ND2 3.26Å; F465-N469 WeakPolarHBondContact O-CB 3.45Å; F465-N469 PolarHBondContact O-N 3.26Å; F465-N469 VanDerWaalsContact O-N 3.13Å; F465-N469 PolarHBondContact O-ND2 3Å; M466-N469 PolarHBondContact O-N 3.34Å; V467-N469 VanDerWaalsContact C-N 3.29Å; V467-N469 PolarHBondContact O-N 3.03Å; N469-L471 VanDerWaalsContact C-N 3.25Å; N469-L471 HydrophobicContact CB-CD1 3.67Å; N469-L471 HydrophobicContact CB-CG 3.71Å; N469-L471 PolarHBondContact O-N 3.13Å
470N94.4Very high95Very high119 Ų11946.6 Ų46.664%0.63623%0.234SC*.THydrogen-bonded Turntrans49.943.1-174.4-55.2-65.8000113M466 V467M466-N470 PolarHBondContact O-N 2.72Å; V467-N470 PolarHBondContact O-N 2.74Å
471L95.9Very high95Very high21 Ų2150.1 Ų50.111%0.1125%0.253CS..  trans-97.1132.3-177.8-62170.5000111.2F465 M466 N469 E475 V476 L483F465-L471 HydrophobicContact CD1-CD1 4.42Å; F465-L471 HydrophobicContact CE1-CD1 3.72Å; F465-L471 HydrophobicContact CZ-CD1 4.26Å; M466-L471 PolarHBondContact O-N 3.09Å; N469-L471 VanDerWaalsContact C-N 3.25Å; N469-L471 HydrophobicContact CB-CD1 3.67Å; N469-L471 HydrophobicContact CB-CG 3.71Å; N469-L471 PolarHBondContact O-N 3.13Å; L471-E475 HydrophobicContact CD2-CB 4.38Å; L471-V476 HydrophobicContact CB-CG2 3.85Å; L471-V476 HydrophobicContact CD1-CG2 4.13Å; L471-L483 HydrophobicContact CD1-CD1 3.91Å; L471-L483 HydrophobicContact CD1-CD2 4.05Å
472T96.7Very high95.1Very high78 Ų7855.2 Ų55.248%0.47928%0.276SS..  trans-80.6163.2164.965.70000110.9A474 E475 V476T472-A474 VanDerWaalsContact C-N 3.31Å; T472-A474 PolarHBondContact O-N 3.15Å; T472-E475 WeakPolarHBondContact CB-OE2 3.48Å; T472-E475 WeakPolarHBondContact CG2-OE2 3.35Å; T472-E475 PolarHBondContact N-OE2 2.89Å; T472-E475 PolarHBondContact O-N 3.01Å; T472-E475 VanDerWaalsContact OG1-CD 3.31Å; T472-E475 WeakPolarHBondContact OG1-CG 3.48Å; T472-E475 PolarHBondContact OG1-N 3.44Å; T472-E475 PolarHBondContact OG1-OE2 2.83Å; T472-V476 WeakPolarHBondContact O-CG2 3.36Å; T472-V476 PolarHBondContact O-N 2.88Å; T472-V476 VanDerWaalsContact O-N 3.11Å
473R95.9Very high95Very high79 Ų7956.6 Ų56.630%0.29828%0.284SS..Hα-helixtrans-53-47.6174162.8175.5168.1156.56.3112.3E441 L445 M466 E475 V476 E477E441-R473 HydrophobicContact CB-CB 4.34Å; E441-R473 WeakPolarHBondContact OE2-CD 3.47Å; L445-R473 HydrophobicContact CD1-CB 4.39Å; L445-R473 HydrophobicContact CD1-CG 4.32Å; L445-R473 HydrophobicContact CD2-CG 3.72Å; L445-R473 HydrophobicContact CG-CB 4.37Å; L445-R473 HydrophobicContact CG-CG 3.8Å; M466-R473 HydrophobicContact CE-CB 4.43Å; R473-E475 VanDerWaalsContact C-N 3.33Å; R473-E475 PolarHBondContact O-N 3.33Å; R473-V476 WeakPolarHBondContact O-CB 3.27Å; R473-V476 PolarHBondContact O-N 2.95Å; R473-V476 VanDerWaalsContact O-N 3.16Å; R473-E477 IonicContact CZ-OE1 3.96Å; R473-E477 IonicContact NE-OE1 2.95Å; R473-E477 PolarHBondContact NE-OE1 3.33Å; R473-E477 IonicContact NE-OE2 3.39Å; R473-E477 PolarHBondContact NE-OE2 3.02Å; R473-E477 IonicContact NH2-OE1 3.17Å; R473-E477 PolarHBondContact NH2-OE1 3.21Å; R473-E477 IonicContact NH2-OE2 3.55Å; R473-E477 PolarHBondContact O-N 2.81Å
474A96.4Very high95Very high62 Ų6261.7 Ų61.751%0.51232%0.319SS..Hα-helixtrans-62-42.3-17600000111.6T472 V476 E477 E478T472-A474 VanDerWaalsContact C-N 3.31Å; T472-A474 PolarHBondContact O-N 3.15Å; A474-V476 VanDerWaalsContact C-N 3.32Å; A474-V476 PolarHBondContact O-N 3.34Å; A474-E477 PolarHBondContact O-N 3.43Å; A474-E478 WeakPolarHBondContact O-CB 3.45Å; A474-E478 PolarHBondContact O-N 2.94Å
475E96.8Very high95.2Very high73 Ų7362.1 Ų62.134%0.34132%0.321SS..Hα-helixtrans-65.1-35.7176.5-68.7164.5133.600112.1L471 T472 R473 R479L471-E475 HydrophobicContact CD2-CB 4.38Å; T472-E475 WeakPolarHBondContact CB-OE2 3.48Å; T472-E475 WeakPolarHBondContact CG2-OE2 3.35Å; T472-E475 PolarHBondContact N-OE2 2.89Å; T472-E475 PolarHBondContact O-N 3.01Å; T472-E475 VanDerWaalsContact OG1-CD 3.31Å; T472-E475 WeakPolarHBondContact OG1-CG 3.48Å; T472-E475 PolarHBondContact OG1-N 3.44Å; T472-E475 PolarHBondContact OG1-OE2 2.83Å; R473-E475 VanDerWaalsContact C-N 3.33Å; R473-E475 PolarHBondContact O-N 3.33Å; E475-R479 WeakPolarHBondContact O-CB 3.48Å; E475-R479 PolarHBondContact O-N 3.45Å
476V97Very high95.2Very high0 Ų062.2 Ų62.20%033%0.325CS..Hα-helixtrans-64.7-41.9173.9174.20000111.5L445 M466 L471 T472 R473 A474 A480 L483 F485 F508L445-V476 HydrophobicContact CD1-CB 4.11Å; L445-V476 HydrophobicContact CD1-CG1 3.88Å; L445-V476 HydrophobicContact CD2-CG1 4.28Å; M466-V476 HydrophobicContact CE-CG2 4.38Å; M466-V476 HydrophobicContact CG-CG2 3.96Å; L471-V476 HydrophobicContact CB-CG2 3.85Å; L471-V476 HydrophobicContact CD1-CG2 4.13Å; T472-V476 WeakPolarHBondContact O-CG2 3.36Å; T472-V476 PolarHBondContact O-N 2.88Å; T472-V476 VanDerWaalsContact O-N 3.11Å; R473-V476 WeakPolarHBondContact O-CB 3.27Å; R473-V476 PolarHBondContact O-N 2.95Å; R473-V476 VanDerWaalsContact O-N 3.16Å; A474-V476 VanDerWaalsContact C-N 3.32Å; A474-V476 PolarHBondContact O-N 3.34Å; V476-A480 WeakPolarHBondContact O-CA 3.33Å; V476-A480 WeakPolarHBondContact O-CB 3.48Å; V476-A480 PolarHBondContact O-N 3.16Å; V476-A480 VanDerWaalsContact O-N 3.08Å; V476-L483 HydrophobicContact CG2-CD1 4.43Å; V476-F485 HydrophobicContact CG1-CE1 3.72Å; V476-F485 HydrophobicContact CG1-CZ 3.88Å; V476-F508 HydrophobicContact CG1-CE2 3.85Å; V476-F508 HydrophobicContact CG1-CZ 4.21Å
477E95.2Very high95.2Very high68 Ų6868.8 Ų68.832%0.31836%0.355SS..Hα-helixtrans-69.2-40.1178.6-68175.1148.200112.5L445 R473 A474 K511L445-E477 HydrophobicContact CD2-CG 3.28Å; R473-E477 IonicContact CZ-OE1 3.96Å; R473-E477 IonicContact NE-OE1 2.95Å; R473-E477 PolarHBondContact NE-OE1 3.33Å; R473-E477 IonicContact NE-OE2 3.39Å; R473-E477 PolarHBondContact NE-OE2 3.02Å; R473-E477 IonicContact NH2-OE1 3.17Å; R473-E477 PolarHBondContact NH2-OE1 3.21Å; R473-E477 IonicContact NH2-OE2 3.55Å; R473-E477 PolarHBondContact O-N 2.81Å; A474-E477 PolarHBondContact O-N 3.43Å; E477-K511 PolarHBondContact O-NZ 3.24Å
478E95.8Very high95.1Very high142 Ų14269.1 Ų69.166%0.66436%0.358SS*.Hα-helixtrans-63.5-49.6178.8-173.1175.2-179.100110.4A474 K511A474-E478 WeakPolarHBondContact O-CB 3.45Å; A474-E478 PolarHBondContact O-N 2.94Å; E478-K511 PolarHBondContact O-NZ 3.36Å
479R95.7Very high95.3Very high97 Ų9765.4 Ų65.437%0.36634%0.341SS..THydrogen-bonded Turntrans-100.220.2-171.4-57.7169.960.6-157.6-4.2114.1E475 D481 E482 L483E475-R479 WeakPolarHBondContact O-CB 3.48Å; E475-R479 PolarHBondContact O-N 3.45Å; R479-D481 PolarHBondContact O-N 3.48Å; R479-D481 VanDerWaalsContact O-N 3.08Å; R479-E482 HydrophobicContact CB-CB 4.46Å; R479-E482 IonicContact NE-OE2 3.64Å; R479-E482 PolarHBondContact NE-OE2 2.66Å; R479-E482 IonicContact NH2-OE2 3.97Å; R479-E482 PolarHBondContact O-N 3.3Å; R479-L483 HydrophobicContact CB-CD1 4.27Å; R479-L483 HydrophobicContact CB-CG 4.26Å; R479-L483 WeakPolarHBondContact O-CG 3.32Å; R479-L483 PolarHBondContact O-N 3.36Å; R479-L483 VanDerWaalsContact O-N 3.15Å
480A95Very high95.5Very high1 Ų162.7 Ų62.71%0.00833%0.327CS..THydrogen-bonded Turntrans-59.8-22.3-17500000114.1V476 F485 F508 K511 V512V476-A480 WeakPolarHBondContact O-CA 3.33Å; V476-A480 WeakPolarHBondContact O-CB 3.48Å; V476-A480 PolarHBondContact O-N 3.16Å; V476-A480 VanDerWaalsContact O-N 3.08Å; A480-F485 HydrophobicContact CB-CZ 4.39Å; A480-F485 WeakPolarHBondContact O-CE2 3.48Å; A480-F508 HydrophobicContact CB-CD2 3.73Å; A480-F508 HydrophobicContact CB-CE2 3.72Å; A480-K511 HydrophobicContact CB-CB 3.71Å; A480-K511 HydrophobicContact CB-CD 3.87Å; A480-K511 HydrophobicContact CB-CG 4.5Å; A480-V512 HydrophobicContact CB-CG2 4.1Å
481D94.8Very high95.5Very high74 Ų7460.3 Ų60.340%0.39631%0.312SS..THydrogen-bonded Turntrans-87.9-9.9175.257.7-35.3000113.6R479 K511 K514R479-D481 PolarHBondContact O-N 3.48Å; R479-D481 VanDerWaalsContact O-N 3.08Å; D481-K511 HydrophobicContact CB-CB 4.24Å; D481-K514 WeakPolarHBondContact O-CE 3.45Å; D481-K514 PolarHBondContact O-NZ 3.21Å
482E94.1Very high95.4Very high129 Ų12959.3 Ų59.360%0.60331%0.307SS*.THydrogen-bonded Turntrans-100.8-30.9177.7-58.8179.417100112.7R479R479-E482 HydrophobicContact CB-CB 4.46Å; R479-E482 IonicContact NE-OE2 3.64Å; R479-E482 PolarHBondContact NE-OE2 2.66Å; R479-E482 IonicContact NH2-OE2 3.97Å; R479-E482 PolarHBondContact O-N 3.3Å
483L95.3Very high95.4Very high29 Ų2955.6 Ų55.615%0.15228%0.284CS..SBendtrans-78.3142.6-172.4-65.9171.6000112.6F465 L471 V476 R479 F485F465-L483 HydrophobicContact CE1-CD1 4.42Å; F465-L483 HydrophobicContact CZ-CB 4.28Å; F465-L483 HydrophobicContact CZ-CD2 4.36Å; L471-L483 HydrophobicContact CD1-CD1 3.91Å; L471-L483 HydrophobicContact CD1-CD2 4.05Å; V476-L483 HydrophobicContact CG2-CD1 4.43Å; R479-L483 HydrophobicContact CB-CD1 4.27Å; R479-L483 HydrophobicContact CB-CG 4.26Å; R479-L483 WeakPolarHBondContact O-CG 3.32Å; R479-L483 PolarHBondContact O-N 3.36Å; R479-L483 VanDerWaalsContact O-N 3.15Å; L483-F485 HydrophobicContact CB-CD2 4.23Å; L483-F485 HydrophobicContact CB-CE2 3.64Å; L483-F485 HydrophobicContact CB-CZ 3.93Å; L483-F485 HydrophobicContact CD1-CZ 4.12Å; L483-F485 WeakPolarHBondContact O-CD2 3.41Å; L483-F485 PolarHBondContact O-N 3.39Å
484S95.3Very high95.4Very high107 Ų10752.7 Ų52.775%0.74827%0.274SS*.  trans-93.293.6172.9-64.70000110.1F465F465-S484 VanDerWaalsContact CE2-O 3.24Å; F465-S484 WeakPolarHBondContact CE2-O 3.31Å
485F96.4Very high95.2Very high22 Ų2249.9 Ų49.910%0.09625%0.251CS..  trans-71.4154.2-177.1-69.6-89.1000112.8L462 F465 V476 A480 L483 V489 V490 F508 V512L462-F485 HydrophobicContact CD1-CD1 3.88Å; L462-F485 HydrophobicContact CD1-CE1 3.99Å; F465-F485 HydrophobicContact CE1-CD1 4.47Å; F465-F485 HydrophobicContact CE1-CE1 4.47Å; V476-F485 HydrophobicContact CG1-CE1 3.72Å; V476-F485 HydrophobicContact CG1-CZ 3.88Å; A480-F485 HydrophobicContact CB-CZ 4.39Å; A480-F485 WeakPolarHBondContact O-CE2 3.48Å; L483-F485 HydrophobicContact CB-CD2 4.23Å; L483-F485 HydrophobicContact CB-CE2 3.64Å; L483-F485 HydrophobicContact CB-CZ 3.93Å; L483-F485 HydrophobicContact CD1-CZ 4.12Å; L483-F485 WeakPolarHBondContact O-CD2 3.41Å; L483-F485 PolarHBondContact O-N 3.39Å; F485-V489 HydrophobicContact CB-CB 4.42Å; F485-V489 HydrophobicContact CB-CG1 4.44Å; F485-V489 HydrophobicContact CD1-CG1 4.32Å; F485-V490 HydrophobicContact CB-CG2 3.99Å; F485-F508 HydrophobicContact CE1-CE2 4.3Å; F485-F508 AromaticContact CE1-CZ 3.9Å; F485-F508 HydrophobicContact CE1-CZ 3.9Å; F485-F508 HydrophobicContact CZ-CE2 4.01Å; F485-F508 HydrophobicContact CZ-CZ 4Å; F485-V512 HydrophobicContact CD2-CB 4.41Å; F485-V512 HydrophobicContact CD2-CG1 3.75Å; F485-V512 HydrophobicContact CD2-CG2 3.91Å; F485-V512 HydrophobicContact CE2-CB 4.47Å; F485-V512 HydrophobicContact CE2-CG1 4.29Å; F485-V512 HydrophobicContact CE2-CG2 3.6Å; F485-V512 HydrophobicContact CG-CG1 4.22Å; F485-V512 HydrophobicContact CZ-CG2 3.99Å
486P95.3Very high94.9Very high30 Ų3051.5 Ų51.520%0.19525%0.254CS..  trans-53.7142.7169.2-23.933.4000111.9D461 F465 S488 V489 V490D461-P486 HydrophobicContact CB-CB 4.02Å; D461-P486 HydrophobicContact CB-CG 4.24Å; F465-P486 HydrophobicContact CB-CG 3.88Å; F465-P486 HydrophobicContact CD2-CG 4.41Å; F465-P486 HydrophobicContact CG-CG 4.26Å; P486-S488 PolarHBondContact O-N 2.92Å; P486-V489 HydrophobicContact CB-CG2 4.16Å; P486-V489 HydrophobicContact CG-CG2 4.26Å; P486-V489 WeakPolarHBondContact O-CB 3.06Å; P486-V489 PolarHBondContact O-N 2.54Å; P486-V490 PolarHBondContact O-N 3.32Å
487Q94.2Very high94.6Very high141 Ų14152.2 Ų52.266%0.65926%0.259SS*.Hα-helixtrans-54.2-40.2-178.4178.8174.3-0.300112.6V489 V490 E491Q487-V489 VanDerWaalsContact C-N 3.29Å; Q487-V489 PolarHBondContact O-N 3.07Å; Q487-V490 PolarHBondContact O-N 3.42Å; Q487-E491 HydrophobicContact CG-CG 4.14Å; Q487-E491 WeakPolarHBondContact CG-OE1 3.05Å; Q487-E491 PolarHBondContact NE2-OE1 3.13Å; Q487-E491 WeakPolarHBondContact O-CB 3.28Å; Q487-E491 WeakPolarHBondContact O-CG 3.14Å; Q487-E491 PolarHBondContact O-N 3.43Å
488S93.1Very high94.4Very high19 Ų1949 Ų4913%0.13324%0.244CC..Hα-helixtrans-59.2-37.7177.954.80000113.1D461 P486 F492D461-S488 WeakPolarHBondContact CB-OG 3.29Å; D461-S488 WeakPolarHBondContact OD2-CB 3.39Å; D461-S488 PolarHBondContact OD2-OG 3.31Å; P486-S488 PolarHBondContact O-N 2.92Å; S488-F492 WeakPolarHBondContact O-CB 3.31Å; S488-F492 PolarHBondContact O-N 3.3Å
489V96.1Very high94.3Very high0 Ų045 Ų450%023%0.226CC..Hα-helixtrans-69.8-44176.4179.90000110.6L446 I458 L462 F485 P486 Q487 F492 L493L446-V489 HydrophobicContact CD2-CG1 4.11Å; I458-V489 HydrophobicContact CG2-CG2 4.15Å; L462-V489 HydrophobicContact CB-CG2 3.82Å; F485-V489 HydrophobicContact CB-CB 4.42Å; F485-V489 HydrophobicContact CB-CG1 4.44Å; F485-V489 HydrophobicContact CD1-CG1 4.32Å; P486-V489 HydrophobicContact CB-CG2 4.16Å; P486-V489 HydrophobicContact CG-CG2 4.26Å; P486-V489 WeakPolarHBondContact O-CB 3.06Å; P486-V489 PolarHBondContact O-N 2.54Å; Q487-V489 VanDerWaalsContact C-N 3.29Å; Q487-V489 PolarHBondContact O-N 3.07Å; V489-F492 PolarHBondContact O-N 3.09Å; V489-L493 HydrophobicContact CG1-CD1 4.1Å; V489-L493 VanDerWaalsContact O-CG 3.3Å; V489-L493 WeakPolarHBondContact O-CG 3.44Å; V489-L493 PolarHBondContact O-N 3.32Å
490V96.3Very high94.2Very high25 Ų2540.5 Ų40.515%0.15221%0.21CC..Hα-helixtrans-61.9-49.7177.3178.60000110.3F485 P486 Q487 F492 L493 Q494 V512 L513 L516F485-V490 HydrophobicContact CB-CG2 3.99Å; P486-V490 PolarHBondContact O-N 3.32Å; Q487-V490 PolarHBondContact O-N 3.42Å; V490-F492 VanDerWaalsContact C-N 3.34Å; V490-F492 PolarHBondContact O-N 2.88Å; V490-L493 PolarHBondContact O-N 3.41Å; V490-L493 VanDerWaalsContact O-N 3.12Å; V490-Q494 HydrophobicContact CG1-CG 4.42Å; V490-Q494 WeakPolarHBondContact O-CG 3.47Å; V490-Q494 PolarHBondContact O-N 3.39Å; V490-V512 HydrophobicContact CG2-CG1 4.29Å; V490-L513 HydrophobicContact CG1-CD2 4.11Å; V490-L516 HydrophobicContact CG1-CD1 3.68Å
491E94.1Very high94.2Very high70 Ų7044.4 Ų44.433%0.32723%0.228SC..Hα-helixtrans-61.9-40179.9-74.1174.5172.700112.4Q487 Q494 G495 Y496Q487-E491 HydrophobicContact CG-CG 4.14Å; Q487-E491 WeakPolarHBondContact CG-OE1 3.05Å; Q487-E491 PolarHBondContact NE2-OE1 3.13Å; Q487-E491 WeakPolarHBondContact O-CB 3.28Å; Q487-E491 WeakPolarHBondContact O-CG 3.14Å; Q487-E491 PolarHBondContact O-N 3.43Å; E491-Q494 PolarHBondContact O-N 3.04Å; E491-G495 PolarHBondContact O-N 3.16Å; E491-Y496 HydrophobicContact CB-CD2 3.99Å; E491-Y496 HydrophobicContact CB-CG 4.42Å; E491-Y496 HydrophobicContact CG-CD2 4.14Å; E491-Y496 WeakPolarHBondContact O-CB 3.45Å; E491-Y496 WeakPolarHBondContact O-CD2 3.32Å; E491-Y496 PolarHBondContact O-N 3.35Å
492F94.9Very high94.2Very high0 Ų044.4 Ų44.40%025%0.245CC..Hα-helixtrans-56.8-52.5170.7164.1-107.8000111.3L225 L446 L449 I458 S488 V489 V490 Q494 G495 P500 F504L225-F492 HydrophobicContact CD1-CE2 4.13Å; L225-F492 HydrophobicContact CD2-CE2 4.38Å; L446-F492 HydrophobicContact CB-CE1 4.22Å; L446-F492 HydrophobicContact CD2-CD1 4.02Å; L446-F492 HydrophobicContact CD2-CE1 3.93Å; L449-F492 HydrophobicContact CD1-CE1 4.07Å; L449-F492 HydrophobicContact CD1-CE2 4.01Å; L449-F492 HydrophobicContact CD1-CZ 3.67Å; L449-F492 HydrophobicContact CD2-CE2 4.32Å; L449-F492 HydrophobicContact CD2-CZ 3.79Å; L449-F492 HydrophobicContact CG-CZ 4.36Å; I458-F492 HydrophobicContact CD1-CB 3.77Å; I458-F492 HydrophobicContact CD1-CD2 4.46Å; I458-F492 HydrophobicContact CD1-CG 4.34Å; I458-F492 HydrophobicContact CG1-CB 4.39Å; I458-F492 HydrophobicContact CG2-CB 3.92Å; I458-F492 HydrophobicContact CG2-CD1 4.35Å; I458-F492 HydrophobicContact CG2-CG 4.19Å; S488-F492 WeakPolarHBondContact O-CB 3.31Å; S488-F492 PolarHBondContact O-N 3.3Å; V489-F492 PolarHBondContact O-N 3.09Å; V490-F492 VanDerWaalsContact C-N 3.34Å; V490-F492 PolarHBondContact O-N 2.88Å; F492-Q494 PolarHBondContact O-N 2.89Å; F492-G495 WeakPolarHBondContact O-CA 3.44Å; F492-G495 PolarHBondContact O-N 2.7Å; F492-P500 HydrophobicContact CE2-CG 4.32Å; F492-P500 HydrophobicContact CZ-CB 4.46Å; F492-P500 HydrophobicContact CZ-CG 4.08Å; F492-F504 HydrophobicContact CD2-CE1 4.37Å; F492-F504 HydrophobicContact CE1-CD1 4.25Å; F492-F504 HydrophobicContact CE1-CE1 4.36Å; F492-F504 HydrophobicContact CE2-CD1 4.48Å; F492-F504 AromaticContact CE2-CE1 3.93Å; F492-F504 HydrophobicContact CE2-CE1 3.93Å; F492-F504 AromaticContact CZ-CD1 4Å; F492-F504 HydrophobicContact CZ-CD1 4Å; F492-F504 AromaticContact CZ-CE1 3.91Å; F492-F504 HydrophobicContact CZ-CE1 3.91Å; F492-F504 WeakPolarHBondContact O-CE1 3.16Å
493L96.1Very high94.2Very high0 Ų039.7 Ų39.70%023%0.232CC..Hα-helixtrans-63.2-31.4-179.4-70.3172.1000112L446 V489 V490 G495 F504 F508 R509 V512 L513L446-L493 HydrophobicContact CD2-CD2 4.5Å; V489-L493 HydrophobicContact CG1-CD1 4.1Å; V489-L493 VanDerWaalsContact O-CG 3.3Å; V489-L493 WeakPolarHBondContact O-CG 3.44Å; V489-L493 PolarHBondContact O-N 3.32Å; V490-L493 PolarHBondContact O-N 3.41Å; V490-L493 VanDerWaalsContact O-N 3.12Å; L493-G495 PolarHBondContact O-N 3.39Å; L493-F504 HydrophobicContact CD2-CD1 4.44Å; L493-F508 HydrophobicContact CD1-CD1 4.38Å; L493-F508 HydrophobicContact CD1-CE1 3.98Å; L493-F508 HydrophobicContact CD2-CD1 4.39Å; L493-R509 HydrophobicContact CB-CG 4.24Å; L493-R509 HydrophobicContact CD2-CB 4.06Å; L493-R509 HydrophobicContact CD2-CG 4.24Å; L493-R509 PolarHBondContact O-NE 3.06Å; L493-R509 PolarHBondContact O-NH2 3.21Å; L493-V512 HydrophobicContact CD1-CB 3.73Å; L493-V512 HydrophobicContact CD1-CG1 3.64Å; L493-V512 HydrophobicContact CD1-CG2 3.93Å; L493-L513 HydrophobicContact CB-CD1 4.41Å; L493-L513 HydrophobicContact CB-CD2 3.9Å; L493-L513 HydrophobicContact CB-CG 4.18Å; L493-L513 WeakPolarHBondContact O-CD1 3.49Å
494Q95.1Very high94.3Very high18 Ų1839.8 Ų39.88%0.08423%0.231CC..Hα-helixtrans-67.1-24.1172.3-70.1-177-78.400112.5V490 E491 F492 Y496 L513 P517 I519V490-Q494 HydrophobicContact CG1-CG 4.42Å; V490-Q494 WeakPolarHBondContact O-CG 3.47Å; V490-Q494 PolarHBondContact O-N 3.39Å; E491-Q494 PolarHBondContact O-N 3.04Å; F492-Q494 PolarHBondContact O-N 2.89Å; Q494-Y496 HydrophobicContact CB-CD2 3.7Å; Q494-Y496 HydrophobicContact CB-CE2 3.84Å; Q494-Y496 HydrophobicContact CG-CE2 4.42Å; Q494-L513 HydrophobicContact CG-CD1 4.21Å; Q494-L513 HydrophobicContact CG-CD2 3.51Å; Q494-P517 VanDerWaalsContact CG-O 3.3Å; Q494-P517 WeakPolarHBondContact CG-O 3.5Å; Q494-P517 PolarHBondContact NE2-O 3.36Å; Q494-I519 PolarHBondContact O-N 2.93Å
495G93.1Very high94.3Very high2 Ų236 Ų362%0.02120%0.203CC..THydrogen-bonded Turntrans104.210.1-179.800000114.3E491 F492 L493 V497 G498 P523E491-G495 PolarHBondContact O-N 3.16Å; F492-G495 WeakPolarHBondContact O-CA 3.44Å; F492-G495 PolarHBondContact O-N 2.7Å; L493-G495 PolarHBondContact O-N 3.39Å; G495-V497 PolarHBondContact O-N 2.78Å; G495-G498 PolarHBondContact O-N 3.27Å; G495-G498 VanDerWaalsContact O-N 3.13Å; G495-P523 WeakPolarHBondContact O-CG 3.33Å
496Y90.9Very high94.2Very high107 Ų10739.4 Ų39.442%0.4222%0.22SC..THydrogen-bonded Turntrans-64.5-12.3-177.6-80.6-81.6000114.7N198 E491 Q494 I519N198-Y496 PolarHBondContact ND2-O 2.77Å; E491-Y496 HydrophobicContact CB-CD2 3.99Å; E491-Y496 HydrophobicContact CB-CG 4.42Å; E491-Y496 HydrophobicContact CG-CD2 4.14Å; E491-Y496 WeakPolarHBondContact O-CB 3.45Å; E491-Y496 WeakPolarHBondContact O-CD2 3.32Å; E491-Y496 PolarHBondContact O-N 3.35Å; Q494-Y496 HydrophobicContact CB-CD2 3.7Å; Q494-Y496 HydrophobicContact CB-CE2 3.84Å; Q494-Y496 HydrophobicContact CG-CE2 4.42Å; Y496-I519 HydrophobicContact CD1-CD1 3.33Å; Y496-I519 HydrophobicContact CD2-CD1 3.81Å; Y496-I519 HydrophobicContact CE1-CD1 3.41Å; Y496-I519 VanDerWaalsContact CE1-CD1 3.41Å; Y496-I519 HydrophobicContact CE2-CD1 3.87Å; Y496-I519 HydrophobicContact CG-CD1 3.54Å
497V89.2Confident94.3Very high16 Ų1642.3 Ų42.310%0.09724%0.239CC..THydrogen-bonded Turntrans-102.8-16.7178.7-176.80000111.9S224 L225 N230 P454 I458 G495S224-V497 VanDerWaalsContact OG-CG1 3.26Å; S224-V497 WeakPolarHBondContact OG-CG1 3.36Å; L225-V497 HydrophobicContact CD1-CG1 4.22Å; L225-V497 HydrophobicContact CG-CG1 4.48Å; N230-V497 PolarHBondContact ND2-O 3.09Å; P454-V497 HydrophobicContact CG-CG1 4.07Å; P454-V497 HydrophobicContact CG-CG2 4.4Å; I458-V497 HydrophobicContact CD1-CG2 3.93Å; G495-V497 PolarHBondContact O-N 2.78Å
498G91.1Very high94.4Very high0 Ų036.2 Ų36.20%021%0.21CC..  trans122.4-175.8-168.800000111.1G495 F504G495-G498 PolarHBondContact O-N 3.27Å; G495-G498 VanDerWaalsContact O-N 3.13Å; G498-F504 WeakPolarHBondContact O-CZ 3.07Å
499I93.6Very high94.5Very high57 Ų5736.8 Ų36.829%0.29221%0.209SC..  trans-105.1122.5-177.3-56177.4000108.7Y227 F504Y227-I499 HydrophobicContact CD2-CB 4.06Å; Y227-I499 WeakPolarHBondContact CD2-O 3.39Å; Y227-I499 HydrophobicContact CE2-CB 3.8Å; Y227-I499 HydrophobicContact CE2-CD1 4.21Å; Y227-I499 HydrophobicContact CE2-CG1 4.12Å; I499-F504 HydrophobicContact CG1-CE2 4.44Å; I499-F504 HydrophobicContact CG2-CE2 4.32Å
500P95.1Very high94.6Very high4 Ų438.7 Ų38.73%0.02622%0.223CC..  trans-68.8151.4178.629.9-36.2000111.4L225 L449 F492 G502 G503 F504L225-P500 HydrophobicContact CD1-CB 4.43Å; L225-P500 HydrophobicContact CD2-CB 4.47Å; L449-P500 HydrophobicContact CD2-CB 3.64Å; L449-P500 HydrophobicContact CD2-CG 4.39Å; F492-P500 HydrophobicContact CE2-CG 4.32Å; F492-P500 HydrophobicContact CZ-CB 4.46Å; F492-P500 HydrophobicContact CZ-CG 4.08Å; P500-G502 PolarHBondContact O-N 2.8Å; P500-G503 WeakPolarHBondContact CG-O 3.18Å; P500-G503 PolarHBondContact O-N 3.18Å; P500-F504 HydrophobicContact CG-CD1 3.95Å; P500-F504 HydrophobicContact CG-CE1 4.04Å; P500-F504 HydrophobicContact CG-CG 4.29Å; P500-F504 HydrophobicContact CG-CZ 4.46Å
501H94.9Very high94.6Very high82 Ų8240.8 Ų40.838%0.3823%0.23SC..THydrogen-bonded Turntrans-58130.2172.6-17566.1000110.7K262 Y263 Y267 G503K262-H501 WeakPolarHBondContact CE-O 3.29Å; K262-H501 PolarHBondContact NZ-O 2.78Å; Y263-H501 HydrophobicContact CE1-CB 4.17Å; Y267-H501 AromaticContact CD2-CE1 3.72Å; Y267-H501 AromaticContact CD2-ND1 4Å; Y267-H501 AromaticContact CD2-NE2 3.75Å; Y267-H501 HydrophobicContact CE2-CB 4.29Å; Y267-H501 AromaticContact CE2-CD2 3.93Å; Y267-H501 AromaticContact CE2-CE1 3.87Å; Y267-H501 AromaticContact CE2-CG 3.69Å; Y267-H501 AromaticContact CE2-ND1 3.65Å; H501-G503 VanDerWaalsContact C-N 3.31Å
502G93.9Very high94.7Very high74 Ų7438.1 Ų38.176%0.76322%0.218SC*.THydrogen-bonded Turntrans82.80.1-173.200000115.1P500P500-G502 PolarHBondContact O-N 2.8Å
503G94.8Very high94.8Very high31 Ų3138.1 Ų38.132%0.3222%0.218SC..  trans80.4178.7-179.300000113.6P500 H501P500-G503 WeakPolarHBondContact CG-O 3.18Å; P500-G503 PolarHBondContact O-N 3.18Å; H501-G503 VanDerWaalsContact C-N 3.31Å
504F96.1Very high94.7Very high30 Ų3044.4 Ų44.413%0.13225%0.245CC..  trans-78.5149.4-179.8-64.9-81.3000111.8F492 L493 G498 I499 P500 E506 R509F492-F504 HydrophobicContact CD2-CE1 4.37Å; F492-F504 HydrophobicContact CE1-CD1 4.25Å; F492-F504 HydrophobicContact CE1-CE1 4.36Å; F492-F504 HydrophobicContact CE2-CD1 4.48Å; F492-F504 AromaticContact CE2-CE1 3.93Å; F492-F504 HydrophobicContact CE2-CE1 3.93Å; F492-F504 AromaticContact CZ-CD1 4Å; F492-F504 HydrophobicContact CZ-CD1 4Å; F492-F504 AromaticContact CZ-CE1 3.91Å; F492-F504 HydrophobicContact CZ-CE1 3.91Å; F492-F504 WeakPolarHBondContact O-CE1 3.16Å; L493-F504 HydrophobicContact CD2-CD1 4.44Å; G498-F504 WeakPolarHBondContact O-CZ 3.07Å; I499-F504 HydrophobicContact CG1-CE2 4.44Å; I499-F504 HydrophobicContact CG2-CE2 4.32Å; P500-F504 HydrophobicContact CG-CD1 3.95Å; P500-F504 HydrophobicContact CG-CE1 4.04Å; P500-F504 HydrophobicContact CG-CG 4.29Å; P500-F504 HydrophobicContact CG-CZ 4.46Å; F504-E506 PolarHBondContact O-N 3.23Å; F504-R509 HydrophobicContact CB-CB 4.32Å; F504-R509 HydrophobicContact CB-CG 4.39Å
505P95.6Very high94.6Very high27 Ų2749.3 Ų49.318%0.17528%0.282CS..  trans-68.8118.1177.428.7-35.4000111.1L445 F508 R509L445-P505 WeakPolarHBondContact O-CG 3.27Å; P505-F508 HydrophobicContact CB-CB 4.39Å; P505-F508 HydrophobicContact CG-CD1 4.13Å; P505-F508 PolarHBondContact O-N 3.45Å; P505-R509 WeakPolarHBondContact O-CB 3.27Å; P505-R509 PolarHBondContact O-N 2.83Å
506E95.4Very high94.6Very high95 Ų9552.9 Ų52.944%0.44430%0.3SS..THydrogen-bonded Turntrans-110144.7171.8-67.5-69.3-176.100110F504 F508 R509 S510 R518F504-E506 PolarHBondContact O-N 3.23Å; E506-F508 VanDerWaalsContact C-N 3.33Å; E506-R509 WeakPolarHBondContact OE1-CD 3.25Å; E506-S510 VanDerWaalsContact CD-OG 3.22Å; E506-S510 PolarHBondContact OE1-OG 3.12Å; E506-S510 VanDerWaalsContact OE1-OG 3.12Å; E506-S510 WeakPolarHBondContact OE2-CB 3.46Å; E506-S510 PolarHBondContact OE2-N 2.84Å; E506-S510 PolarHBondContact OE2-OG 2.68Å; E506-R518 IonicContact OE1-NH1 2.65Å
507P95.8Very high94.7Very high91 Ų9151.9 Ų51.959%0.59131%0.307SS*.THydrogen-bonded Turncis-83.75.4634.9-36.9000114.6R509 S510 K511P507-R509 PolarHBondContact O-N 3.31Å; P507-S510 PolarHBondContact O-N 3.03Å; P507-K511 PolarHBondContact O-N 2.74Å
508F96.8Very high95Very high12 Ų1256.3 Ų56.35%0.05332%0.322CS..Hα-helixtrans-56-51.5-175.2-178.2-108000112.4L446 V476 A480 F485 L493 P505 E506 S510 K511 V512L446-F508 HydrophobicContact CD2-CE1 4.15Å; V476-F508 HydrophobicContact CG1-CE2 3.85Å; V476-F508 HydrophobicContact CG1-CZ 4.21Å; A480-F508 HydrophobicContact CB-CD2 3.73Å; A480-F508 HydrophobicContact CB-CE2 3.72Å; F485-F508 HydrophobicContact CE1-CE2 4.3Å; F485-F508 AromaticContact CE1-CZ 3.9Å; F485-F508 HydrophobicContact CE1-CZ 3.9Å; F485-F508 HydrophobicContact CZ-CE2 4.01Å; F485-F508 HydrophobicContact CZ-CZ 4Å; L493-F508 HydrophobicContact CD1-CD1 4.38Å; L493-F508 HydrophobicContact CD1-CE1 3.98Å; L493-F508 HydrophobicContact CD2-CD1 4.39Å; P505-F508 HydrophobicContact CB-CB 4.39Å; P505-F508 HydrophobicContact CG-CD1 4.13Å; P505-F508 PolarHBondContact O-N 3.45Å; E506-F508 VanDerWaalsContact C-N 3.33Å; F508-S510 VanDerWaalsContact C-N 3.34Å; F508-S510 PolarHBondContact O-N 3.08Å; F508-K511 PolarHBondContact O-N 2.85Å; F508-V512 HydrophobicContact CD1-CG2 4.39Å; F508-V512 HydrophobicContact CD2-CG2 4.28Å; F508-V512 HydrophobicContact CE1-CG2 4.02Å; F508-V512 HydrophobicContact CE2-CG2 3.88Å; F508-V512 HydrophobicContact CZ-CG2 3.75Å; F508-V512 WeakPolarHBondContact O-CG2 3.22Å; F508-V512 PolarHBondContact O-N 2.87Å
509R96.8Very high95Very high31 Ų3158 Ų5812%0.11733%0.33CS..Hα-helixtrans-53.7-49.9175.4179.5-169.1-170.4-162.86.7111.3L493 F504 P505 E506 P507 K511 V512 L513L493-R509 HydrophobicContact CB-CG 4.24Å; L493-R509 HydrophobicContact CD2-CB 4.06Å; L493-R509 HydrophobicContact CD2-CG 4.24Å; L493-R509 PolarHBondContact O-NE 3.06Å; L493-R509 PolarHBondContact O-NH2 3.21Å; F504-R509 HydrophobicContact CB-CB 4.32Å; F504-R509 HydrophobicContact CB-CG 4.39Å; P505-R509 WeakPolarHBondContact O-CB 3.27Å; P505-R509 PolarHBondContact O-N 2.83Å; E506-R509 WeakPolarHBondContact OE1-CD 3.25Å; P507-R509 PolarHBondContact O-N 3.31Å; R509-K511 VanDerWaalsContact C-N 3.33Å; R509-K511 PolarHBondContact O-N 2.95Å; R509-V512 PolarHBondContact O-N 2.9Å; R509-L513 HydrophobicContact CG-CD1 3.75Å; R509-L513 HydrophobicContact CG-CG 4.16Å; R509-L513 WeakPolarHBondContact O-CB 3.42Å; R509-L513 WeakPolarHBondContact O-CG 3.35Å; R509-L513 PolarHBondContact O-N 3.14Å
510S96.8Very high94.6Very high41 Ų4163.9 Ų63.929%0.28736%0.357SS..Hα-helixtrans-63.3-37.6-178.2-67.80000113E506 P507 F508 K514 R518E506-S510 VanDerWaalsContact CD-OG 3.22Å; E506-S510 PolarHBondContact OE1-OG 3.12Å; E506-S510 VanDerWaalsContact OE1-OG 3.12Å; E506-S510 WeakPolarHBondContact OE2-CB 3.46Å; E506-S510 PolarHBondContact OE2-N 2.84Å; E506-S510 PolarHBondContact OE2-OG 2.68Å; P507-S510 PolarHBondContact O-N 3.03Å; F508-S510 VanDerWaalsContact C-N 3.34Å; F508-S510 PolarHBondContact O-N 3.08Å; S510-K514 PolarHBondContact O-N 3.33Å; S510-R518 PolarHBondContact OG-NH2 3.25Å
511K96.9Very high94.3Very high68 Ų6865.1 Ų65.130%0.29637%0.37SS..Hα-helixtrans-65.2-45.3174.6-74-172.4175.2-170.10112.8E477 E478 A480 D481 P507 F508 R509 K514E477-K511 PolarHBondContact O-NZ 3.24Å; E478-K511 PolarHBondContact O-NZ 3.36Å; A480-K511 HydrophobicContact CB-CB 3.71Å; A480-K511 HydrophobicContact CB-CD 3.87Å; A480-K511 HydrophobicContact CB-CG 4.5Å; D481-K511 HydrophobicContact CB-CB 4.24Å; P507-K511 PolarHBondContact O-N 2.74Å; F508-K511 PolarHBondContact O-N 2.85Å; R509-K511 VanDerWaalsContact C-N 3.33Å; R509-K511 PolarHBondContact O-N 2.95Å; K511-K514 VanDerWaalsContact O-CG 3.26Å; K511-K514 WeakPolarHBondContact O-CG 3.49Å
512V96.7Very high94.2Very high14 Ų1463.2 Ų63.29%0.08536%0.359CS..Hα-helixtrans-67.7-45.7-179.3176.70000111.2A480 F485 V490 L493 F508 R509A480-V512 HydrophobicContact CB-CG2 4.1Å; F485-V512 HydrophobicContact CD2-CB 4.41Å; F485-V512 HydrophobicContact CD2-CG1 3.75Å; F485-V512 HydrophobicContact CD2-CG2 3.91Å; F485-V512 HydrophobicContact CE2-CB 4.47Å; F485-V512 HydrophobicContact CE2-CG1 4.29Å; F485-V512 HydrophobicContact CE2-CG2 3.6Å; F485-V512 HydrophobicContact CG-CG1 4.22Å; F485-V512 HydrophobicContact CZ-CG2 3.99Å; V490-V512 HydrophobicContact CG2-CG1 4.29Å; L493-V512 HydrophobicContact CD1-CB 3.73Å; L493-V512 HydrophobicContact CD1-CG1 3.64Å; L493-V512 HydrophobicContact CD1-CG2 3.93Å; F508-V512 HydrophobicContact CD1-CG2 4.39Å; F508-V512 HydrophobicContact CD2-CG2 4.28Å; F508-V512 HydrophobicContact CE1-CG2 4.02Å; F508-V512 HydrophobicContact CE2-CG2 3.88Å; F508-V512 HydrophobicContact CZ-CG2 3.75Å; F508-V512 WeakPolarHBondContact O-CG2 3.22Å; F508-V512 PolarHBondContact O-N 2.87Å; R509-V512 PolarHBondContact O-N 2.9Å
513L96.4Very high93.9Very high1 Ų159.9 Ų59.91%0.00533%0.325CS..Hα-helixtrans-77.1-33.4-175.3-64.4-170.8000113.1V490 L493 Q494 R509 S515 L516 R518V490-L513 HydrophobicContact CG1-CD2 4.11Å; L493-L513 HydrophobicContact CB-CD1 4.41Å; L493-L513 HydrophobicContact CB-CD2 3.9Å; L493-L513 HydrophobicContact CB-CG 4.18Å; L493-L513 WeakPolarHBondContact O-CD1 3.49Å; Q494-L513 HydrophobicContact CG-CD1 4.21Å; Q494-L513 HydrophobicContact CG-CD2 3.51Å; R509-L513 HydrophobicContact CG-CD1 3.75Å; R509-L513 HydrophobicContact CG-CG 4.16Å; R509-L513 WeakPolarHBondContact O-CB 3.42Å; R509-L513 WeakPolarHBondContact O-CG 3.35Å; R509-L513 PolarHBondContact O-N 3.14Å; L513-S515 PolarHBondContact O-N 2.86Å; L513-L516 HydrophobicContact CB-CB 4.3Å; L513-L516 HydrophobicContact CD2-CB 4.46Å; L513-L516 HydrophobicContact CD2-CD1 4.35Å; L513-L516 WeakPolarHBondContact O-CB 3.39Å; L513-L516 VanDerWaalsContact O-CG 3.25Å; L513-L516 WeakPolarHBondContact O-CG 3.29Å; L513-L516 PolarHBondContact O-N 2.8Å; L513-R518 HydrophobicContact CD1-CG 3.88Å
514K93.9Very high93.6Very high131 Ų13158.5 Ų58.557%0.5731%0.31SS*.THydrogen-bonded Turntrans51.9-111.5-173.2-52.1173.8-175.9173.60110.1D481 S510 K511D481-K514 WeakPolarHBondContact O-CE 3.45Å; D481-K514 PolarHBondContact O-NZ 3.21Å; S510-K514 PolarHBondContact O-N 3.33Å; K511-K514 VanDerWaalsContact O-CG 3.26Å; K511-K514 WeakPolarHBondContact O-CG 3.49Å
515S93Very high93.3Very high121 Ų12160 Ų6085%0.84633%0.328SS*.THydrogen-bonded Turntrans-97.66.3177.862.60000114.5L513L513-S515 PolarHBondContact O-N 2.86Å
516L94.2Very high92.9Very high77 Ų7763.5 Ų63.540%0.40335%0.353SS..SBendtrans-63.3145.2176.5-69.8176.4000110.9V490 L513V490-L516 HydrophobicContact CG1-CD1 3.68Å; L513-L516 HydrophobicContact CB-CB 4.3Å; L513-L516 HydrophobicContact CD2-CB 4.46Å; L513-L516 HydrophobicContact CD2-CD1 4.35Å; L513-L516 WeakPolarHBondContact O-CB 3.39Å; L513-L516 VanDerWaalsContact O-CG 3.25Å; L513-L516 WeakPolarHBondContact O-CG 3.29Å; L513-L516 PolarHBondContact O-N 2.8Å
517P92.8Very high92.7Very high86 Ų8662.7 Ų62.756%0.55835%0.351SS*.  trans-63.9145.9-177.726-33.3000111.1Q494Q494-P517 VanDerWaalsContact CG-O 3.3Å; Q494-P517 WeakPolarHBondContact CG-O 3.5Å; Q494-P517 PolarHBondContact NE2-O 3.36Å
518R94.1Very high92.7Very high110 Ų11063.1 Ų63.142%0.41536%0.357SS..  trans-113.1139.9176.8-61.1176.1-172.9-160.2-3108.4E506 S510 L513E506-R518 IonicContact OE1-NH1 2.65Å; S510-R518 PolarHBondContact OG-NH2 3.25Å; L513-R518 HydrophobicContact CD1-CG 3.88Å
519I90.9Very high92.7Very high34 Ų3467.5 Ų67.517%0.17439%0.386CS..  trans-94.6131.1174.2-62.1172.5000107.9Q494 Y496 P523Q494-I519 PolarHBondContact O-N 2.93Å; Y496-I519 HydrophobicContact CD1-CD1 3.33Å; Y496-I519 HydrophobicContact CD2-CD1 3.81Å; Y496-I519 HydrophobicContact CE1-CD1 3.41Å; Y496-I519 VanDerWaalsContact CE1-CD1 3.41Å; Y496-I519 HydrophobicContact CE2-CD1 3.87Å; Y496-I519 HydrophobicContact CG-CD1 3.54Å; I519-P523 HydrophobicContact CD1-CB 4.31Å; I519-P523 HydrophobicContact CG2-CB 4.19Å; I519-P523 HydrophobicContact CG2-CG 4.08Å
520E86.3Confident92.7Very high182 Ų18268.4 Ų68.485%0.8539%0.392SS*.  trans-106.7137171.4-63.9-171.5171.500109.5
521G88.1Confident92.7Very high30 Ų3071.2 Ų71.231%0.30940%0.404SS..SBendtrans71.2-150.5-177.600000113.8
522R92.4Very high92.7Very high41 Ų4170.1 Ų70.116%0.15540%0.4CS..  trans-80.4122.2-176.6-178.2167.468.172.12.5111D201 N230 G524 A525D201-R522 IonicContact OD1-CZ 2.78Å; D201-R522 IonicContact OD1-NH1 3.9Å; D201-R522 PolarHBondContact OD1-NH1 3.21Å; D201-R522 IonicContact OD1-NH2 3.14Å; D201-R522 PolarHBondContact OD1-NH2 3.44Å; D201-R522 IonicContact OD2-CZ 2.95Å; D201-R522 IonicContact OD2-NH1 2.72Å; D201-R522 IonicContact OD2-NH2 2.99Å; D201-R522 PolarHBondContact OD2-NH2 3.16Å; N230-R522 WeakPolarHBondContact OD1-CD 3.49Å; N230-R522 VanDerWaalsContact OD1-CG 3.26Å; N230-R522 WeakPolarHBondContact OD1-CG 3.34Å; R522-G524 VanDerWaalsContact C-N 3.34Å; R522-G524 PolarHBondContact O-N 3.18Å; R522-A525 HydrophobicContact CB-CB 4.28Å; R522-A525 WeakPolarHBondContact O-CB 3.48Å; R522-A525 PolarHBondContact O-N 2.78Å; R522-A525 VanDerWaalsContact O-N 3.11Å
523P88Confident92.8Very high5 Ų576.5 Ų76.53%0.03243%0.426CS..G310 helixtrans-59.5-40.1-173.5-26.535.6000114.2N198 G495 I519 A525 S526N198-P523 HydrophobicContact CB-CB 3.92Å; N198-P523 WeakPolarHBondContact ND2-CB 3.49Å; N198-P523 WeakPolarHBondContact ND2-CG 3.37Å; G495-P523 WeakPolarHBondContact O-CG 3.33Å; I519-P523 HydrophobicContact CD1-CB 4.31Å; I519-P523 HydrophobicContact CG2-CB 4.19Å; I519-P523 HydrophobicContact CG2-CG 4.08Å; P523-A525 VanDerWaalsContact C-N 3.27Å; P523-A525 PolarHBondContact O-N 3.13Å; P523-S526 PolarHBondContact O-OG 3.43Å; P523-S526 VanDerWaalsContact O-OG 3.07Å
524G89.1Confident92.8Very high1 Ų179 Ų791%0.0145%0.447CS..G310 helixtrans-66.3-23.418000000114.8Y199 R522 S526 L527Y199-G524 WeakPolarHBondContact O-CA 3.43Å; R522-G524 VanDerWaalsContact C-N 3.34Å; R522-G524 PolarHBondContact O-N 3.18Å; G524-S526 PolarHBondContact O-N 3.34Å; G524-L527 WeakPolarHBondContact O-CB 3.05Å; G524-L527 PolarHBondContact O-N 2.88Å; G524-L527 VanDerWaalsContact O-N 3.12Å
525A90.2Very high93Very high63 Ų6375.2 Ų75.252%0.52143%0.433SS..G310 helixtrans-66.6-24.4-175.900000113.2R522 P523R522-A525 HydrophobicContact CB-CB 4.28Å; R522-A525 WeakPolarHBondContact O-CB 3.48Å; R522-A525 PolarHBondContact O-N 2.78Å; R522-A525 VanDerWaalsContact O-N 3.11Å; P523-A525 VanDerWaalsContact C-N 3.27Å; P523-A525 PolarHBondContact O-N 3.13Å
526S86.1Confident93.2Very high99 Ų9972.4 Ų72.469%0.69241%0.406SS*.G310 helixtrans-89.4-9.5178.966.80000113.7P523 G524P523-S526 PolarHBondContact O-OG 3.43Å; P523-S526 VanDerWaalsContact O-OG 3.07Å; G524-S526 PolarHBondContact O-N 3.34Å
527L91.8Very high93.3Very high78 Ų7872.9 Ų72.941%0.40841%0.409SS..SBendtrans-80.4138.6-176.9-59.3178.7000110.3P200 G524P200-L527 HydrophobicContact CB-CB 4.21Å; P200-L527 HydrophobicContact CG-CB 3.86Å; P200-L527 HydrophobicContact CG-CD1 4.37Å; G524-L527 WeakPolarHBondContact O-CB 3.05Å; G524-L527 PolarHBondContact O-N 2.88Å; G524-L527 VanDerWaalsContact O-N 3.12Å
528S95.4Very high93.5Very high100 Ų10070.8 Ų70.870%0.69940%0.403SS*.PPolyproline II helixtrans-64.1143.4173.1-60.70000110.5P200 M530P200-S528 WeakPolarHBondContact CB-O 3.09Å; P200-S528 WeakPolarHBondContact CG-O 3.41Å; S528-M530 PolarHBondContact O-N 3.06Å
529P96.8Very high93.6Very high105 Ų10566.2 Ų66.268%0.68239%0.387SS*.PPolyproline II helixtrans-52.2139.6175.4-26.734.6000111.8N202N202-P529 WeakPolarHBondContact OD1-CA 3.06Å
530M96.3Very high93.7Very high49 Ų4968 Ų6824%0.24139%0.391CS..PPolyproline II helixtrans-71.6132.9176.4-173.3170.4-69.300110.7P200 N202 A203 S528 F532 L535 A556P200-M530 HydrophobicContact CG-CB 4.48Å; N202-M530 PolarHBondContact ND2-N 3.43Å; N202-M530 PolarHBondContact ND2-O 3.33Å; N202-M530 PolarHBondContact OD1-N 3.36Å; A203-M530 HydrophobicContact CB-CE 4.5Å; S528-M530 PolarHBondContact O-N 3.06Å; M530-F532 HydrophobicContact CB-CE1 4.08Å; M530-F532 HydrophobicContact CB-CZ 4.06Å; M530-F532 HydrophobicContact CG-CD1 4.15Å; M530-F532 HydrophobicContact CG-CE1 3.91Å; M530-F532 HydrophobicContact CG-CZ 4.41Å; M530-F532 PolarHBondContact O-N 2.97Å; M530-F532 HydrophobicContact SD-CD1 4.09Å; M530-F532 HydrophobicContact SD-CE1 3.63Å; M530-F532 HydrophobicContact SD-CZ 4.46Å; M530-L535 HydrophobicContact SD-CD2 4.32Å; M530-A556 HydrophobicContact CE-CB 4.2Å; M530-A556 HydrophobicContact SD-CB 3.45Å; M530-A556 WeakPolarHBondContact SD-CB 3.25Å
531D97.8Very high94Very high100 Ų10063.6 Ų63.654%0.53539%0.387SS..  trans-87.792.8172.4-171.6-19.3000110.1K533 A534 L535D531-K533 VanDerWaalsContact C-N 3.27Å; D531-K533 PolarHBondContact O-N 2.76Å; D531-K533 PolarHBondContact OD1-N 3.28Å; D531-K533 VanDerWaalsContact OD1-N 3.11Å; D531-A534 HydrophobicContact CB-CB 4.02Å; D531-A534 VanDerWaalsContact CG-CB 3.46Å; D531-A534 PolarHBondContact OD1-N 2.84Å; D531-L535 PolarHBondContact O-N 3.32Å; D531-L535 VanDerWaalsContact O-N 3.1Å
532F97.6Very high94.1Very high46 Ų4665.4 Ų65.420%0.20240%0.399CS..Hα-helixtrans-65.9-29.7-179.7-59.8-65.5000113N202 A203 K206 M530 L535 E536 V552 M553N202-F532 HydrophobicContact CB-CE2 4.46Å; N202-F532 VanDerWaalsContact ND2-CE2 3.29Å; N202-F532 WeakPolarHBondContact ND2-CE2 3.33Å; A203-F532 HydrophobicContact CB-CE1 4.45Å; A203-F532 HydrophobicContact CB-CZ 4.18Å; K206-F532 HydrophobicContact CB-CE2 4.1Å; K206-F532 HydrophobicContact CB-CZ 3.92Å; K206-F532 HydrophobicContact CG-CE2 4.34Å; K206-F532 HydrophobicContact CG-CZ 4.33Å; M530-F532 HydrophobicContact CB-CE1 4.08Å; M530-F532 HydrophobicContact CB-CZ 4.06Å; M530-F532 HydrophobicContact CG-CD1 4.15Å; M530-F532 HydrophobicContact CG-CE1 3.91Å; M530-F532 HydrophobicContact CG-CZ 4.41Å; M530-F532 PolarHBondContact O-N 2.97Å; M530-F532 HydrophobicContact SD-CD1 4.09Å; M530-F532 HydrophobicContact SD-CE1 3.63Å; M530-F532 HydrophobicContact SD-CZ 4.46Å; F532-L535 PolarHBondContact O-N 3.18Å; F532-E536 WeakPolarHBondContact O-CB 3.49Å; F532-E536 PolarHBondContact O-N 3.04Å; F532-V552 HydrophobicContact CB-CG1 4.37Å; F532-V552 HydrophobicContact CD1-CG1 4.27Å; F532-M553 HydrophobicContact CD1-SD 4.46Å; F532-M553 HydrophobicContact CE1-SD 4.06Å
533K97Very high93.8Very high147 Ų14766.3 Ų66.364%0.63940%0.404SS*.Hα-helixtrans-71-46.7-179.9-175.2179.6179.3-177.30110.3D531 L535 E536 D537D531-K533 VanDerWaalsContact C-N 3.27Å; D531-K533 PolarHBondContact O-N 2.76Å; D531-K533 PolarHBondContact OD1-N 3.28Å; D531-K533 VanDerWaalsContact OD1-N 3.11Å; K533-L535 VanDerWaalsContact C-N 3.26Å; K533-L535 PolarHBondContact O-N 3.24Å; K533-E536 PolarHBondContact O-N 3.31Å; K533-D537 WeakPolarHBondContact O-CB 3.36Å; K533-D537 VanDerWaalsContact O-CG 3.29Å; K533-D537 PolarHBondContact O-N 3.15Å
534A97.4Very high93.7Very high54 Ų5467.6 Ų67.645%0.44642%0.419SS..Hα-helixtrans-61.1-38.1174.700000111.9D531 G538D531-A534 HydrophobicContact CB-CB 4.02Å; D531-A534 VanDerWaalsContact CG-CB 3.46Å; D531-A534 PolarHBondContact OD1-N 2.84Å; A534-G538 PolarHBondContact O-N 2.99Å
535L97.4Very high93.4Very high51 Ų5173.6 Ų73.627%0.26745%0.451SS..Hα-helixtrans-63.3-47.7174.3-179.659000111.4M530 D531 F532 K533 G538 L539 V552 A555 A556M530-L535 HydrophobicContact SD-CD2 4.32Å; D531-L535 PolarHBondContact O-N 3.32Å; D531-L535 VanDerWaalsContact O-N 3.1Å; F532-L535 PolarHBondContact O-N 3.18Å; K533-L535 VanDerWaalsContact C-N 3.26Å; K533-L535 PolarHBondContact O-N 3.24Å; L535-G538 PolarHBondContact O-N 2.72Å; L535-L539 HydrophobicContact CD1-CG 4.41Å; L535-L539 HydrophobicContact CG-CD1 4.37Å; L535-L539 VanDerWaalsContact O-CG 3.31Å; L535-L539 WeakPolarHBondContact O-CG 3.33Å; L535-L539 PolarHBondContact O-N 3.11Å; L535-V552 HydrophobicContact CD2-CG1 3.98Å; L535-V552 HydrophobicContact CG-CG1 4.29Å; L535-A555 HydrophobicContact CD1-CB 4.41Å; L535-A555 HydrophobicContact CD2-CB 4.42Å; L535-A556 HydrophobicContact CD2-CB 3.9Å
536E97.4Very high93.1Very high63 Ų6377.5 Ų77.529%0.29446%0.463SS..Hα-helixtrans-59.8-48.4177.3-172.5-177.1167.500112F532 K533 G538 L539 R540 I547 V552F532-E536 WeakPolarHBondContact O-CB 3.49Å; F532-E536 PolarHBondContact O-N 3.04Å; K533-E536 PolarHBondContact O-N 3.31Å; E536-G538 VanDerWaalsContact C-N 3.28Å; E536-G538 PolarHBondContact O-N 3.21Å; E536-L539 PolarHBondContact O-N 3.26Å; E536-L539 VanDerWaalsContact O-N 3.12Å; E536-R540 WeakPolarHBondContact O-CG 3.41Å; E536-R540 PolarHBondContact O-N 3.01Å; E536-R540 IonicContact OE1-CZ 2.73Å; E536-R540 VanDerWaalsContact OE1-CZ 3.26Å; E536-R540 IonicContact OE1-NE 3.72Å; E536-R540 PolarHBondContact OE1-NE 3.4Å; E536-R540 IonicContact OE1-NH2 3.29Å; E536-R540 PolarHBondContact OE1-NH2 3.34Å; E536-I547 HydrophobicContact CG-CG2 4.27Å; E536-V552 HydrophobicContact CB-CG2 3.81Å; E536-V552 HydrophobicContact CG-CG2 3.86Å
537D96.9Very high93.5Very high87 Ų8773.2 Ų73.247%0.46543%0.432SS..Hα-helixtrans-58.8-41.5178-70.9-22.6000111.1K533 R540 A541K533-D537 WeakPolarHBondContact O-CB 3.36Å; K533-D537 VanDerWaalsContact O-CG 3.29Å; K533-D537 PolarHBondContact O-N 3.15Å; D537-R540 PolarHBondContact O-N 3.33Å; D537-A541 WeakPolarHBondContact O-CB 3.49Å; D537-A541 PolarHBondContact O-N 2.94Å
538G96.6Very high93.6Very high42 Ų4272.3 Ų72.343%0.43343%0.43SS..Hα-helixtrans-64.4-40.8174.900000113.3A534 L535 E536 A541 A542A534-G538 PolarHBondContact O-N 2.99Å; L535-G538 PolarHBondContact O-N 2.72Å; E536-G538 VanDerWaalsContact C-N 3.28Å; E536-G538 PolarHBondContact O-N 3.21Å; G538-A541 PolarHBondContact O-N 2.64Å; G538-A542 WeakPolarHBondContact O-CB 3.43Å; G538-A542 PolarHBondContact O-N 2.9Å; G538-A542 VanDerWaalsContact O-N 3.12Å
539L95.6Very high93.6Very high14 Ų1471.1 Ų71.17%0.07342%0.42CS..Hα-helixtrans-66.4-41.8175.9-70.3177.7000111.8L535 E536 A541 A542 H543 I547 V552 A555 F562L535-L539 HydrophobicContact CD1-CG 4.41Å; L535-L539 HydrophobicContact CG-CD1 4.37Å; L535-L539 VanDerWaalsContact O-CG 3.31Å; L535-L539 WeakPolarHBondContact O-CG 3.33Å; L535-L539 PolarHBondContact O-N 3.11Å; E536-L539 PolarHBondContact O-N 3.26Å; E536-L539 VanDerWaalsContact O-N 3.12Å; L539-A541 VanDerWaalsContact C-N 3.34Å; L539-A541 PolarHBondContact O-N 3.39Å; L539-A542 PolarHBondContact O-N 2.8Å; L539-H543 WeakPolarHBondContact O-CB 3.45Å; L539-H543 PolarHBondContact O-N 2.83Å; L539-I547 HydrophobicContact CB-CD1 4.04Å; L539-I547 HydrophobicContact CB-CG1 3.97Å; L539-I547 HydrophobicContact CB-CG2 4.11Å; L539-I547 HydrophobicContact CD1-CG2 4.2Å; L539-V552 HydrophobicContact CD1-CG2 4.25Å; L539-A555 HydrophobicContact CD1-CB 3.71Å; L539-A555 HydrophobicContact CD2-CB 4.12Å; L539-A555 HydrophobicContact CG-CB 4.43Å; L539-F562 HydrophobicContact CD1-CE1 4.29Å; L539-F562 HydrophobicContact CD2-CD1 4.22Å; L539-F562 HydrophobicContact CD2-CE1 3.81Å
540R94.6Very high93.7Very high70 Ų7067.5 Ų67.526%0.26439%0.394SS..Hα-helixtrans-61.6-42.9176.5-71.8176.3179.6-69.9-12.3111.4E536 D537 A542 G544 D545 I547E536-R540 WeakPolarHBondContact O-CG 3.41Å; E536-R540 PolarHBondContact O-N 3.01Å; E536-R540 IonicContact OE1-CZ 2.73Å; E536-R540 VanDerWaalsContact OE1-CZ 3.26Å; E536-R540 IonicContact OE1-NE 3.72Å; E536-R540 PolarHBondContact OE1-NE 3.4Å; E536-R540 IonicContact OE1-NH2 3.29Å; E536-R540 PolarHBondContact OE1-NH2 3.34Å; D537-R540 PolarHBondContact O-N 3.33Å; R540-A542 VanDerWaalsContact C-N 3.31Å; R540-A542 PolarHBondContact O-N 3.08Å; R540-G544 WeakPolarHBondContact CA-O 3.44Å; R540-G544 CarbonylContact O-C 3.53Å; R540-G544 VanDerWaalsContact O-CA 3.26Å; R540-G544 WeakPolarHBondContact O-CA 3.3Å; R540-G544 PolarHBondContact O-N 3.19Å; R540-D545 PolarHBondContact NH1-O 3.07Å; R540-I547 HydrophobicContact CG-CB 4.02Å; R540-I547 HydrophobicContact CG-CG1 4Å; R540-I547 PolarHBondContact NH2-O 3.38Å; R540-I547 VanDerWaalsContact NH2-O 3.11Å
541A92.4Very high93.7Very high91 Ų9166 Ų6675%0.75239%0.387SS*.Hα-helixtrans-63.1-35.3175.700000113.1D537 G538 L539D537-A541 WeakPolarHBondContact O-CB 3.49Å; D537-A541 PolarHBondContact O-N 2.94Å; G538-A541 PolarHBondContact O-N 2.64Å; L539-A541 VanDerWaalsContact C-N 3.34Å; L539-A541 PolarHBondContact O-N 3.39Å
542A89.7Confident93.7Very high68 Ų6861.6 Ų61.656%0.56236%0.364SS*.Hα-helixtrans-83.2-35.5-177.900000113.8G538 L539 R540G538-A542 WeakPolarHBondContact O-CB 3.43Å; G538-A542 PolarHBondContact O-N 2.9Å; G538-A542 VanDerWaalsContact O-N 3.12Å; L539-A542 PolarHBondContact O-N 2.8Å; R540-A542 VanDerWaalsContact C-N 3.31Å; R540-A542 PolarHBondContact O-N 3.08Å
543H86.3Confident93.7Very high59 Ų5959.6 Ų59.627%0.27336%0.355SS..Hα-helixtrans-124-2.8-166.6-61-73.5000114.4L539 I547 Q563 K566L539-H543 WeakPolarHBondContact O-CB 3.45Å; L539-H543 PolarHBondContact O-N 2.83Å; H543-I547 HydrophobicContact CB-CD1 4.11Å; H543-Q563 PolarHBondContact CE1-OE1 3.38Å; H543-Q563 VanDerWaalsContact CE1-OE1 3.28Å; H543-Q563 PolarHBondContact NE2-OE1 3.06Å; H543-K566 VanDerWaalsContact CE1-CB 3.48Å; H543-K566 WeakPolarHBondContact CE1-CB 3.22Å
544G84.6Confident93.7Very high33 Ų3352.7 Ų52.734%0.3433%0.325SS..  trans92.8-179.9-176.300000113.4R540 D546R540-G544 WeakPolarHBondContact CA-O 3.44Å; R540-G544 CarbonylContact O-C 3.53Å; R540-G544 VanDerWaalsContact O-CA 3.26Å; R540-G544 WeakPolarHBondContact O-CA 3.3Å; R540-G544 PolarHBondContact O-N 3.19Å; G544-D546 VanDerWaalsContact C-N 3.26Å; G544-D546 PolarHBondContact O-N 2.99Å
545D82.9Confident93.6Very high126 Ų12650.2 Ų50.267%0.67431%0.305SS*.SBendtrans-76.6-5.7-169.8-64.3-44.2000115.1R540 I547R540-D545 PolarHBondContact NH1-O 3.07Å; D545-I547 PolarHBondContact O-N 3.21Å
546D85.3Confident93.5Very high145 Ų14548.1 Ų48.178%0.77530%0.295SS*.  trans-84.349.4179.7-63.5-29.1000111.9G544G544-D546 VanDerWaalsContact C-N 3.26Å; G544-D546 PolarHBondContact O-N 2.99Å
547I93.7Very high93.4Very high9 Ų945.3 Ų45.35%0.04628%0.281CS..  trans-102.1128.3174.5-63.1-60.1000109.6E536 L539 R540 H543 D545 D551 V552E536-I547 HydrophobicContact CG-CG2 4.27Å; L539-I547 HydrophobicContact CB-CD1 4.04Å; L539-I547 HydrophobicContact CB-CG1 3.97Å; L539-I547 HydrophobicContact CB-CG2 4.11Å; L539-I547 HydrophobicContact CD1-CG2 4.2Å; R540-I547 HydrophobicContact CG-CB 4.02Å; R540-I547 HydrophobicContact CG-CG1 4Å; R540-I547 PolarHBondContact NH2-O 3.38Å; R540-I547 VanDerWaalsContact NH2-O 3.11Å; H543-I547 HydrophobicContact CB-CD1 4.11Å; D545-I547 PolarHBondContact O-N 3.21Å; I547-D551 HydrophobicContact CD1-CB 4.48Å; I547-D551 HydrophobicContact CG2-CB 4.09Å; I547-V552 HydrophobicContact CG2-CG2 3.92Å
548T95Very high93.3Very high60 Ų6041.7 Ų41.737%0.36826%0.262SS..  trans-106.3165.2179.578.50000111.7E550 D551 V552T548-E550 WeakPolarHBondContact CB-OE2 3.22Å; T548-E550 PolarHBondContact O-N 2.75Å; T548-E550 PolarHBondContact OG1-N 3.39Å; T548-E550 PolarHBondContact OG1-OE2 2.9Å; T548-D551 WeakPolarHBondContact O-CB 3.49Å; T548-D551 PolarHBondContact O-N 3.37Å; T548-D551 PolarHBondContact OG1-N 3.06Å; T548-V552 PolarHBondContact O-N 3.09Å
549P94.9Very high93.2Very high74 Ų7443.9 Ų43.948%0.48127%0.268SS..Hα-helixtrans-55.7-34.6173-26.236.2000113.4V552 M553P549-V552 PolarHBondContact O-N 3.01Å; P549-M553 WeakPolarHBondContact O-CG 3.38Å; P549-M553 PolarHBondContact O-N 3.29Å
550E97.4Very high93.2Very high29 Ų2950.2 Ų50.214%0.13630%0.295CS..Hα-helixtrans-64.4-39.5174.7-63.679.1-167.500112.5W169 V210 N214 T548 M553 S554W169-E550 HydrophobicContact CB-CB 3.93Å; W169-E550 HydrophobicContact CB-CG 3.79Å; W169-E550 HydrophobicContact CD2-CB 3.8Å; W169-E550 HydrophobicContact CD2-CG 3.69Å; W169-E550 HydrophobicContact CE3-CB 4.49Å; W169-E550 HydrophobicContact CE3-CG 3.9Å; W169-E550 HydrophobicContact CG-CB 3.52Å; W169-E550 HydrophobicContact CG-CG 3.66Å; W169-E550 PolarHBondContact NE1-O 2.96Å; V210-E550 HydrophobicContact CG1-CG 4.12Å; N214-E550 PolarHBondContact ND2-OE1 3.27Å; N214-E550 PolarHBondContact OD1-OE1 3.49Å; T548-E550 WeakPolarHBondContact CB-OE2 3.22Å; T548-E550 PolarHBondContact O-N 2.75Å; T548-E550 PolarHBondContact OG1-N 3.39Å; T548-E550 PolarHBondContact OG1-OE2 2.9Å; E550-M553 PolarHBondContact O-N 3.09Å; E550-S554 WeakPolarHBondContact O-CB 3.44Å; E550-S554 PolarHBondContact O-N 2.75Å; E550-S554 PolarHBondContact O-OG 3.15Å
551D97Very high93.3Very high17 Ų1747.1 Ų47.19%0.09128%0.284CS..Hα-helixtrans-65-43.4174.8-89.63.8000110.3I547 T548 M553 S554 A555 F562 K566I547-D551 HydrophobicContact CD1-CB 4.48Å; I547-D551 HydrophobicContact CG2-CB 4.09Å; T548-D551 WeakPolarHBondContact O-CB 3.49Å; T548-D551 PolarHBondContact O-N 3.37Å; T548-D551 PolarHBondContact OG1-N 3.06Å; D551-M553 PolarHBondContact O-N 2.58Å; D551-S554 PolarHBondContact O-N 3.44Å; D551-A555 WeakPolarHBondContact O-CB 3.24Å; D551-A555 PolarHBondContact O-N 2.78Å; D551-F562 HydrophobicContact CB-CE2 3.97Å; D551-F562 HydrophobicContact CB-CZ 3.63Å; D551-F562 WeakPolarHBondContact OD1-CE2 3.37Å; D551-K566 IonicContact OD2-NZ 3.89Å; D551-K566 PolarHBondContact OD2-NZ 3.35Å
552V97.5Very high93.4Very high9 Ų942.9 Ų42.96%0.05525%0.248CC..Hα-helixtrans-59.6-45.6174.9178.70000110.7F532 L535 E536 L539 I547 T548 P549 A555 A556F532-V552 HydrophobicContact CB-CG1 4.37Å; F532-V552 HydrophobicContact CD1-CG1 4.27Å; L535-V552 HydrophobicContact CD2-CG1 3.98Å; L535-V552 HydrophobicContact CG-CG1 4.29Å; E536-V552 HydrophobicContact CB-CG2 3.81Å; E536-V552 HydrophobicContact CG-CG2 3.86Å; L539-V552 HydrophobicContact CD1-CG2 4.25Å; I547-V552 HydrophobicContact CG2-CG2 3.92Å; T548-V552 PolarHBondContact O-N 3.09Å; P549-V552 PolarHBondContact O-N 3.01Å; V552-A555 PolarHBondContact O-N 2.87Å; V552-A556 WeakPolarHBondContact O-CB 3.37Å; V552-A556 PolarHBondContact O-N 3.08Å
553M97.2Very high93.7Very high3 Ų342.9 Ų42.92%0.01524%0.237CC..Hα-helixtrans-68.7-35.7178.7-72.3-49.1-51.800113.1W169 K206 F207 V210 F532 P549 E550 D551 A556 M557W169-M553 HydrophobicContact CZ2-CB 3.95Å; K206-M553 HydrophobicContact CB-CE 4.43Å; K206-M553 HydrophobicContact CB-SD 3.94Å; K206-M553 HydrophobicContact CG-CG 4.44Å; K206-M553 HydrophobicContact CG-SD 3.52Å; K206-M553 VanDerWaalsContact CG-SD 3.52Å; F207-M553 HydrophobicContact CB-CE 3.71Å; F207-M553 HydrophobicContact CD2-CE 4.12Å; F207-M553 HydrophobicContact CG-CE 4.43Å; V210-M553 HydrophobicContact CB-CG 4.34Å; V210-M553 HydrophobicContact CG2-CG 3.99Å; F532-M553 HydrophobicContact CD1-SD 4.46Å; F532-M553 HydrophobicContact CE1-SD 4.06Å; P549-M553 WeakPolarHBondContact O-CG 3.38Å; P549-M553 PolarHBondContact O-N 3.29Å; E550-M553 PolarHBondContact O-N 3.09Å; D551-M553 PolarHBondContact O-N 2.58Å; M553-A556 HydrophobicContact CE-CB 4.41Å; M553-A556 PolarHBondContact O-N 2.96Å; M553-M557 HydrophobicContact CE-CE 3.45Å; M553-M557 VanDerWaalsContact CE-CE 3.45Å; M553-M557 WeakPolarHBondContact O-CB 3.46Å; M553-M557 VanDerWaalsContact O-CG 3.28Å; M553-M557 WeakPolarHBondContact O-CG 3.31Å; M553-M557 PolarHBondContact O-N 3.46Å
554S97.2Very high94.1Very high2 Ų244 Ų441%0.01424%0.242CC..Hα-helixtrans-64.1-43.1173.8-55.90000111.3W169 E550 D551 Y558 F562W169-S554 PolarHBondContact NE1-OG 3.12Å; E550-S554 WeakPolarHBondContact O-CB 3.44Å; E550-S554 PolarHBondContact O-N 2.75Å; E550-S554 PolarHBondContact O-OG 3.15Å; D551-S554 PolarHBondContact O-N 3.44Å; S554-Y558 CarbonylContact O-C 3.55Å; S554-Y558 WeakPolarHBondContact O-CA 3.45Å; S554-Y558 PolarHBondContact O-N 2.72Å; S554-F562 VanDerWaalsContact CB-CD2 3.48Å
555A96.6Very high94.6Very high3 Ų343.3 Ų43.33%0.02523%0.23CC..Hα-helixtrans-68-36.6175.400000112.6L535 L539 D551 V552 P559 F562L535-A555 HydrophobicContact CD1-CB 4.41Å; L535-A555 HydrophobicContact CD2-CB 4.42Å; L539-A555 HydrophobicContact CD1-CB 3.71Å; L539-A555 HydrophobicContact CD2-CB 4.12Å; L539-A555 HydrophobicContact CG-CB 4.43Å; D551-A555 WeakPolarHBondContact O-CB 3.24Å; D551-A555 PolarHBondContact O-N 2.78Å; V552-A555 PolarHBondContact O-N 2.87Å; A555-P559 WeakPolarHBondContact O-CA 3.44Å; A555-P559 WeakPolarHBondContact O-CB 3.22Å; A555-P559 WeakPolarHBondContact O-CD 3.46Å; A555-P559 WeakPolarHBondContact O-CG 3.29Å; A555-P559 VanDerWaalsContact O-N 3.1Å; A555-F562 HydrophobicContact CB-CB 4.38Å; A555-F562 HydrophobicContact CB-CD1 3.62Å; A555-F562 HydrophobicContact CB-CE1 4.09Å; A555-F562 HydrophobicContact CB-CG 4.02Å
556A95.6Very high95.1Very high6 Ų639.1 Ų39.15%0.0521%0.206CC..Hα-helixtrans-63.3-44.9176.300000111.8M530 L535 V552 M553M530-A556 HydrophobicContact CE-CB 4.2Å; M530-A556 HydrophobicContact SD-CB 3.45Å; M530-A556 WeakPolarHBondContact SD-CB 3.25Å; L535-A556 HydrophobicContact CD2-CB 3.9Å; V552-A556 WeakPolarHBondContact O-CB 3.37Å; V552-A556 PolarHBondContact O-N 3.08Å; M553-A556 HydrophobicContact CE-CB 4.41Å; M553-A556 PolarHBondContact O-N 2.96Å
557M94.6Very high95.5Very high4 Ų437 Ų372%0.0219%0.191CC..Hα-helixtrans-79.4-36.7-178.4-63.7-62.5144.500112.2A193 V194 Y199 A203 F207 M553A193-M557 HydrophobicContact CB-SD 4.35Å; V194-M557 HydrophobicContact CG2-CG 4.37Å; Y199-M557 HydrophobicContact CD1-SD 4.35Å; Y199-M557 HydrophobicContact CD2-CE 4.45Å; Y199-M557 HydrophobicContact CD2-SD 3.76Å; Y199-M557 HydrophobicContact CE1-SD 4.18Å; Y199-M557 HydrophobicContact CE2-SD 3.55Å; Y199-M557 VanDerWaalsContact CE2-SD 3.55Å; Y199-M557 HydrophobicContact CG-CE 4.48Å; Y199-M557 HydrophobicContact CG-SD 4.17Å; Y199-M557 PolarHBondContact OH-O 3.05Å; A203-M557 HydrophobicContact CB-CE 3.8Å; A203-M557 WeakPolarHBondContact O-CE 3.47Å; F207-M557 HydrophobicContact CB-CE 4.12Å; F207-M557 HydrophobicContact CD2-CE 4.37Å; F207-M557 HydrophobicContact CD2-CG 4.02Å; F207-M557 HydrophobicContact CE2-CG 4.42Å; M553-M557 HydrophobicContact CE-CE 3.45Å; M553-M557 VanDerWaalsContact CE-CE 3.45Å; M553-M557 WeakPolarHBondContact O-CB 3.46Å; M553-M557 VanDerWaalsContact O-CG 3.28Å; M553-M557 WeakPolarHBondContact O-CG 3.31Å; M553-M557 PolarHBondContact O-N 3.46Å
558Y95.3Very high95.5Very high12 Ų1237.9 Ų37.95%0.04720%0.195CC..  trans-140.166.3-172.9-70.9-78.4000112.7F157 D158 M161 V194 G195 Y196 S554 K560 V561 F562F157-Y558 AromaticContact CD1-CD2 3.83Å; F157-Y558 HydrophobicContact CD1-CD2 3.83Å; F157-Y558 AromaticContact CD1-CE2 3.81Å; F157-Y558 HydrophobicContact CD1-CE2 3.81Å; F157-Y558 AromaticContact CE1-CD2 4Å; F157-Y558 HydrophobicContact CE1-CD2 4Å; F157-Y558 HydrophobicContact CE1-CE2 4.38Å; D158-Y558 HydrophobicContact CB-CE1 3.95Å; D158-Y558 HydrophobicContact CB-CE2 4.3Å; M161-Y558 HydrophobicContact CE-CD2 4.25Å; M161-Y558 HydrophobicContact CE-CG 4.5Å; V194-Y558 HydrophobicContact CG2-CE2 4.21Å; V194-Y558 PolarHBondContact O-OH 2.91Å; G195-Y558 WeakPolarHBondContact CA-OH 3.42Å; Y196-Y558 AromaticContact CD2-CE1 3.75Å; Y196-Y558 HydrophobicContact CD2-CE1 3.75Å; Y196-Y558 AromaticContact CE2-CE1 3.82Å; Y196-Y558 HydrophobicContact CE2-CE1 3.82Å; S554-Y558 CarbonylContact O-C 3.55Å; S554-Y558 WeakPolarHBondContact O-CA 3.45Å; S554-Y558 PolarHBondContact O-N 2.72Å; Y558-K560 PolarHBondContact O-N 3.26Å; Y558-V561 HydrophobicContact CD1-CG2 3.9Å; Y558-V561 HydrophobicContact CG-CG2 4.29Å; Y558-V561 PolarHBondContact O-N 3.33Å; Y558-V561 VanDerWaalsContact O-N 3.11Å; Y558-F562 WeakPolarHBondContact O-CB 3.41Å; Y558-F562 PolarHBondContact O-N 3.33Å
559P94.4Very high95.3Very high88 Ų8836.7 Ų36.757%0.57119%0.187SC*.Hα-helixtrans-54.8-47.8-170-20.524.6000113.6A555 Q563A555-P559 WeakPolarHBondContact O-CA 3.44Å; A555-P559 WeakPolarHBondContact O-CB 3.22Å; A555-P559 WeakPolarHBondContact O-CD 3.46Å; A555-P559 WeakPolarHBondContact O-CG 3.29Å; A555-P559 VanDerWaalsContact O-N 3.1Å; P559-Q563 WeakPolarHBondContact O-CB 2.97Å; P559-Q563 PolarHBondContact O-N 3.24Å; P559-Q563 VanDerWaalsContact O-N 3.08Å
560K94.9Very high95Very high146 Ų14636.7 Ų36.764%0.63519%0.189SC*.Hα-helixtrans-67.6-42.3-179.6-179.2174.6173.61790112.4Y558 Q563 E564Y558-K560 PolarHBondContact O-N 3.26Å; K560-Q563 PolarHBondContact O-N 3.11Å; K560-E564 WeakPolarHBondContact CE-OE1 3.5Å; K560-E564 IonicContact NZ-OE1 3.84Å; K560-E564 WeakPolarHBondContact O-CG 3.22Å; K560-E564 PolarHBondContact O-N 3.34Å
561V95.7Very high94.7Very high5 Ų539.8 Ų39.83%0.0321%0.206CC..Hα-helixtrans-68.8-42.3-177.6-168.20000110.4M161 R162 Y558 Q563 E564 F565M161-V561 HydrophobicContact CB-CG1 3.92Å; R162-V561 HydrophobicContact CB-CG1 3.7Å; R162-V561 HydrophobicContact CG-CG1 4.32Å; R162-V561 VanDerWaalsContact CZ-CG2 3.45Å; Y558-V561 HydrophobicContact CD1-CG2 3.9Å; Y558-V561 HydrophobicContact CG-CG2 4.29Å; Y558-V561 PolarHBondContact O-N 3.33Å; Y558-V561 VanDerWaalsContact O-N 3.11Å; V561-Q563 VanDerWaalsContact C-N 3.33Å; V561-E564 PolarHBondContact O-N 2.9Å; V561-F565 VanDerWaalsContact O-CB 3.3Å; V561-F565 WeakPolarHBondContact O-CB 3.37Å; V561-F565 PolarHBondContact O-N 2.92Å
562F96.3Very high94.4Very high2 Ų240 Ų401%0.00921%0.207CC..Hα-helixtrans-61.8-43.8176.4-179-100.6000111M161 L539 D551 S554 A555 Y558 F565 K566M161-F562 HydrophobicContact SD-CD2 4.34Å; L539-F562 HydrophobicContact CD1-CE1 4.29Å; L539-F562 HydrophobicContact CD2-CD1 4.22Å; L539-F562 HydrophobicContact CD2-CE1 3.81Å; D551-F562 HydrophobicContact CB-CE2 3.97Å; D551-F562 HydrophobicContact CB-CZ 3.63Å; D551-F562 WeakPolarHBondContact OD1-CE2 3.37Å; S554-F562 VanDerWaalsContact CB-CD2 3.48Å; A555-F562 HydrophobicContact CB-CB 4.38Å; A555-F562 HydrophobicContact CB-CD1 3.62Å; A555-F562 HydrophobicContact CB-CE1 4.09Å; A555-F562 HydrophobicContact CB-CG 4.02Å; Y558-F562 WeakPolarHBondContact O-CB 3.41Å; Y558-F562 PolarHBondContact O-N 3.33Å; F562-F565 HydrophobicContact CD2-CD1 4.36Å; F562-F565 HydrophobicContact CE2-CD1 4.49Å; F562-F565 WeakPolarHBondContact O-CB 3.47Å; F562-F565 PolarHBondContact O-N 3.26Å; F562-K566 HydrophobicContact CD1-CG 4.13Å; F562-K566 HydrophobicContact CE1-CD 4.16Å; F562-K566 HydrophobicContact CE1-CG 3.65Å; F562-K566 HydrophobicContact CE2-CD 4.07Å; F562-K566 HydrophobicContact CE2-CG 4.12Å; F562-K566 HydrophobicContact CZ-CD 3.66Å; F562-K566 HydrophobicContact CZ-CG 3.65Å; F562-K566 WeakPolarHBondContact O-CG 3.4Å; F562-K566 PolarHBondContact O-N 3.44Å
563Q94.9Very high93.8Very high68 Ų6839.9 Ų39.932%0.31821%0.207SC..Hα-helixtrans-59.1-48.9174.4-178.760.630.100111.9H543 P559 K560 V561 F565 K566 E567H543-Q563 PolarHBondContact CE1-OE1 3.38Å; H543-Q563 VanDerWaalsContact CE1-OE1 3.28Å; H543-Q563 PolarHBondContact NE2-OE1 3.06Å; P559-Q563 WeakPolarHBondContact O-CB 2.97Å; P559-Q563 PolarHBondContact O-N 3.24Å; P559-Q563 VanDerWaalsContact O-N 3.08Å; K560-Q563 PolarHBondContact O-N 3.11Å; V561-Q563 VanDerWaalsContact C-N 3.33Å; Q563-F565 VanDerWaalsContact C-N 3.29Å; Q563-F565 PolarHBondContact O-N 3.34Å; Q563-K566 PolarHBondContact O-N 3.17Å; Q563-E567 PolarHBondContact NE2-OE1 3.38Å; Q563-E567 WeakPolarHBondContact O-CG 3.4Å; Q563-E567 PolarHBondContact O-N 2.98Å
564E95.1Very high93.4Very high84 Ų8441.5 Ų41.539%0.39322%0.218SC..Hα-helixtrans-59.7-38.7176.3-72.6170.3-179.800111.8K560 V561 E567 F568K560-E564 WeakPolarHBondContact CE-OE1 3.5Å; K560-E564 IonicContact NZ-OE1 3.84Å; K560-E564 WeakPolarHBondContact O-CG 3.22Å; K560-E564 PolarHBondContact O-N 3.34Å; V561-E564 PolarHBondContact O-N 2.9Å; E564-E567 PolarHBondContact O-N 3.14Å; E564-F568 WeakPolarHBondContact O-CB 3.43Å; E564-F568 PolarHBondContact O-N 3.4Å
565F95.6Very high93.2Very high18 Ų1841.4 Ų41.48%0.07922%0.217CC..Hα-helixtrans-66.3-43.2175.7168.6-109.9000112.6M161 C167 V561 F562 Q563 F568 T569M161-F565 HydrophobicContact CB-CB 4.18Å; M161-F565 HydrophobicContact CB-CD2 4.45Å; M161-F565 HydrophobicContact CB-CG 4.25Å; M161-F565 HydrophobicContact CG-CD1 4.48Å; M161-F565 HydrophobicContact CG-CG 4.35Å; C167-F565 HydrophobicContact CB-CZ 4.1Å; V561-F565 VanDerWaalsContact O-CB 3.3Å; V561-F565 WeakPolarHBondContact O-CB 3.37Å; V561-F565 PolarHBondContact O-N 2.92Å; F562-F565 HydrophobicContact CD2-CD1 4.36Å; F562-F565 HydrophobicContact CE2-CD1 4.49Å; F562-F565 WeakPolarHBondContact O-CB 3.47Å; F562-F565 PolarHBondContact O-N 3.26Å; Q563-F565 VanDerWaalsContact C-N 3.29Å; Q563-F565 PolarHBondContact O-N 3.34Å; F565-F568 PolarHBondContact O-N 3.33Å; F565-T569 HydrophobicContact CD2-CG2 3.97Å; F565-T569 HydrophobicContact CE1-CG2 4.49Å; F565-T569 HydrophobicContact CE2-CG2 3.48Å; F565-T569 VanDerWaalsContact CE2-CG2 3.48Å; F565-T569 HydrophobicContact CZ-CG2 3.79Å; F565-T569 WeakPolarHBondContact O-CB 3.18Å; F565-T569 WeakPolarHBondContact O-CG2 3.4Å; F565-T569 PolarHBondContact O-N 2.89Å; F565-T569 PolarHBondContact O-OG1 2.86Å
566K93.4Very high92.9Very high38 Ų3842.6 Ų42.617%0.16522%0.223CC..Hα-helixtrans-66-38.7175.5-66-67.2-79.8-156.20111.5H543 D551 F562 Q563 T569 S570H543-K566 VanDerWaalsContact CE1-CB 3.48Å; H543-K566 WeakPolarHBondContact CE1-CB 3.22Å; D551-K566 IonicContact OD2-NZ 3.89Å; D551-K566 PolarHBondContact OD2-NZ 3.35Å; F562-K566 HydrophobicContact CD1-CG 4.13Å; F562-K566 HydrophobicContact CE1-CD 4.16Å; F562-K566 HydrophobicContact CE1-CG 3.65Å; F562-K566 HydrophobicContact CE2-CD 4.07Å; F562-K566 HydrophobicContact CE2-CG 4.12Å; F562-K566 HydrophobicContact CZ-CD 3.66Å; F562-K566 HydrophobicContact CZ-CG 3.65Å; F562-K566 WeakPolarHBondContact O-CG 3.4Å; F562-K566 PolarHBondContact O-N 3.44Å; Q563-K566 PolarHBondContact O-N 3.17Å; K566-T569 WeakPolarHBondContact CA-OG1 3.42Å; K566-T569 PolarHBondContact O-OG1 2.87Å; K566-T569 VanDerWaalsContact O-OG1 3.11Å; K566-S570 VanDerWaalsContact O-CB 3.23Å; K566-S570 WeakPolarHBondContact O-CB 3.43Å; K566-S570 PolarHBondContact O-N 3.39Å
567E92.3Very high92.7Very high100 Ų10043.6 Ų43.647%0.46723%0.229SC..Hα-helixtrans-63.1-44.6172.7-73.2173.7-165.900111.9Q563 E564 S570 N571Q563-E567 PolarHBondContact NE2-OE1 3.38Å; Q563-E567 WeakPolarHBondContact O-CG 3.4Å; Q563-E567 PolarHBondContact O-N 2.98Å; E564-E567 PolarHBondContact O-N 3.14Å; E567-S570 PolarHBondContact O-N 3.32Å; E567-N571 PolarHBondContact O-N 3.43Å; E567-N571 VanDerWaalsContact O-N 3.15Å; E567-N571 PolarHBondContact O-ND2 3.04Å
568F93.9Very high92.7Very high27 Ų2743.4 Ų43.412%0.11823%0.228CC..Hα-helixtrans-59.8-54.1176.9-178.5-80.4000111.4Y48 T58 E564 F565 S570 N571 F572 V575Y48-F568 HydrophobicContact CD2-CE2 4.49Å; Y48-F568 AromaticContact CD2-CZ 3.81Å; Y48-F568 HydrophobicContact CD2-CZ 3.81Å; Y48-F568 HydrophobicContact CE2-CE2 4.25Å; Y48-F568 AromaticContact CE2-CZ 3.64Å; Y48-F568 HydrophobicContact CE2-CZ 3.64Å; T58-F568 HydrophobicContact CG2-CE2 4.15Å; E564-F568 WeakPolarHBondContact O-CB 3.43Å; E564-F568 PolarHBondContact O-N 3.4Å; F565-F568 PolarHBondContact O-N 3.33Å; F568-S570 VanDerWaalsContact C-N 3.26Å; F568-S570 PolarHBondContact O-N 3.49Å; F568-N571 PolarHBondContact O-N 3.4Å; F568-F572 HydrophobicContact CD1-CB 4.27Å; F568-F572 HydrophobicContact CD1-CD2 4.33Å; F568-F572 AromaticContact CD2-CD2 3.69Å; F568-F572 HydrophobicContact CD2-CD2 3.69Å; F568-F572 HydrophobicContact CD2-CE2 4.2Å; F568-F572 HydrophobicContact CE1-CB 3.82Å; F568-F572 HydrophobicContact CE1-CD2 4.13Å; F568-F572 HydrophobicContact CE1-CG 4.42Å; F568-F572 AromaticContact CE2-CD2 3.47Å; F568-F572 HydrophobicContact CE2-CD2 3.47Å; F568-F572 VanDerWaalsContact CE2-CD2 3.47Å; F568-F572 AromaticContact CE2-CE2 3.99Å; F568-F572 HydrophobicContact CE2-CE2 3.99Å; F568-F572 HydrophobicContact CE2-CG 4.37Å; F568-F572 HydrophobicContact CG-CD2 4.12Å; F568-F572 HydrophobicContact CZ-CB 4.03Å; F568-F572 AromaticContact CZ-CD2 3.72Å; F568-F572 HydrophobicContact CZ-CD2 3.72Å; F568-F572 HydrophobicContact CZ-CG 4.18Å; F568-F572 PolarHBondContact O-N 2.88Å; F568-V575 HydrophobicContact CE1-CB 4.42Å; F568-V575 HydrophobicContact CE1-CG1 3.77Å; F568-V575 HydrophobicContact CE1-CG2 3.74Å; F568-V575 HydrophobicContact CZ-CG1 4.11Å; F568-V575 HydrophobicContact CZ-CG2 4.28Å
569T91Very high92.7Very high35 Ų3543.9 Ų43.922%0.21523%0.233CC..Hα-helixtrans-64.7-30.7-178.450.70000112.4F565 K566 N571 G573F565-T569 HydrophobicContact CD2-CG2 3.97Å; F565-T569 HydrophobicContact CE1-CG2 4.49Å; F565-T569 HydrophobicContact CE2-CG2 3.48Å; F565-T569 VanDerWaalsContact CE2-CG2 3.48Å; F565-T569 HydrophobicContact CZ-CG2 3.79Å; F565-T569 WeakPolarHBondContact O-CB 3.18Å; F565-T569 WeakPolarHBondContact O-CG2 3.4Å; F565-T569 PolarHBondContact O-N 2.89Å; F565-T569 PolarHBondContact O-OG1 2.86Å; K566-T569 WeakPolarHBondContact CA-OG1 3.42Å; K566-T569 PolarHBondContact O-OG1 2.87Å; K566-T569 VanDerWaalsContact O-OG1 3.11Å; T569-N571 VanDerWaalsContact C-N 3.34Å; T569-G573 VanDerWaalsContact O-CA 3.24Å; T569-G573 WeakPolarHBondContact O-CA 3.41Å; T569-G573 PolarHBondContact O-N 3.18Å
570S89.1Confident92.8Very high74 Ų7439.7 Ų39.752%0.51721%0.206SC..Hα-helixtrans-62.9-40.1170.6-171.80000112K44 K566 E567 F568K44-S570 WeakPolarHBondContact CD-O 2.97Å; K44-S570 WeakPolarHBondContact CE-O 3.32Å; K44-S570 PolarHBondContact NZ-O 3.39Å; K566-S570 VanDerWaalsContact O-CB 3.23Å; K566-S570 WeakPolarHBondContact O-CB 3.43Å; K566-S570 PolarHBondContact O-N 3.39Å; E567-S570 PolarHBondContact O-N 3.32Å; F568-S570 VanDerWaalsContact C-N 3.26Å; F568-S570 PolarHBondContact O-N 3.49Å
571N90Very high92.8Very high94 Ų9433.8 Ų33.850%0.50318%0.18SC..Hα-helixtrans-82.8-38.9-177.9-71.2-40.4000114.5H47 E567 F568 T569H47-N571 PolarHBondContact ND1-O 3.25Å; E567-N571 PolarHBondContact O-N 3.43Å; E567-N571 VanDerWaalsContact O-N 3.15Å; E567-N571 PolarHBondContact O-ND2 3.04Å; F568-N571 PolarHBondContact O-N 3.4Å; T569-N571 VanDerWaalsContact C-N 3.34Å
572F92Very high92.7Very high23 Ų2333.8 Ų33.810%0.10118%0.18CC..Hα-helixtrans-115.6-11-168.8-69.2-55.2000114.4K44 L45 H47 Y48 H51 F568 V575K44-F572 CarbonylContact C-O 3.57Å; K44-F572 WeakPolarHBondContact CB-O 3.29Å; K44-F572 VanDerWaalsContact O-O 3.11Å; L45-F572 PolarHBondContact N-O 3.46Å; H47-F572 AromaticContact CE1-CE1 3.88Å; H47-F572 AromaticContact ND1-CD1 3.95Å; H47-F572 AromaticContact ND1-CE1 3.8Å; Y48-F572 VanDerWaalsContact CA-CD1 3.44Å; Y48-F572 HydrophobicContact CD2-CB 4.07Å; Y48-F572 AromaticContact CD2-CD1 3.99Å; Y48-F572 HydrophobicContact CD2-CD1 3.99Å; Y48-F572 HydrophobicContact CD2-CD2 4.28Å; Y48-F572 HydrophobicContact CD2-CE1 4.49Å; Y48-F572 AromaticContact CD2-CG 3.86Å; Y48-F572 HydrophobicContact CD2-CG 3.86Å; Y48-F572 HydrophobicContact CG-CB 4.41Å; Y48-F572 HydrophobicContact CG-CD1 4.34Å; Y48-F572 HydrophobicContact CG-CG 4.45Å; H51-F572 HydrophobicContact CB-CE1 3.89Å; H51-F572 HydrophobicContact CB-CZ 4.12Å; H51-F572 AromaticContact CG-CZ 3.97Å; H51-F572 AromaticContact ND1-CZ 3.98Å; F568-F572 HydrophobicContact CD1-CB 4.27Å; F568-F572 HydrophobicContact CD1-CD2 4.33Å; F568-F572 AromaticContact CD2-CD2 3.69Å; F568-F572 HydrophobicContact CD2-CD2 3.69Å; F568-F572 HydrophobicContact CD2-CE2 4.2Å; F568-F572 HydrophobicContact CE1-CB 3.82Å; F568-F572 HydrophobicContact CE1-CD2 4.13Å; F568-F572 HydrophobicContact CE1-CG 4.42Å; F568-F572 AromaticContact CE2-CD2 3.47Å; F568-F572 HydrophobicContact CE2-CD2 3.47Å; F568-F572 VanDerWaalsContact CE2-CD2 3.47Å; F568-F572 AromaticContact CE2-CE2 3.99Å; F568-F572 HydrophobicContact CE2-CE2 3.99Å; F568-F572 HydrophobicContact CE2-CG 4.37Å; F568-F572 HydrophobicContact CG-CD2 4.12Å; F568-F572 HydrophobicContact CZ-CB 4.03Å; F568-F572 AromaticContact CZ-CD2 3.72Å; F568-F572 HydrophobicContact CZ-CD2 3.72Å; F568-F572 HydrophobicContact CZ-CG 4.18Å; F568-F572 PolarHBondContact O-N 2.88Å; F572-V575 HydrophobicContact CB-CG1 4.33Å
573G84.6Confident92.7Very high5 Ų533.7 Ų33.75%0.05218%0.179CC..  trans73.2-164.8178.300000112.7T569 V575T569-G573 VanDerWaalsContact O-CA 3.24Å; T569-G573 WeakPolarHBondContact O-CA 3.41Å; T569-G573 PolarHBondContact O-N 3.18Å; G573-V575 PolarHBondContact O-N 3.49Å
574P87.7Confident92.7Very high37 Ų3730.6 Ų30.624%0.2417%0.165CC..  trans-77.989.9-173.831.7-34.3000111.1L45 D576 C577 L597L45-P574 WeakPolarHBondContact CD2-O 3.47Å; P574-D576 VanDerWaalsContact C-OD1 3.24Å; P574-D576 WeakPolarHBondContact CA-OD1 3.4Å; P574-D576 VanDerWaalsContact CB-OD1 3.23Å; P574-D576 WeakPolarHBondContact CB-OD1 3.41Å; P574-D576 PolarHBondContact O-N 3.39Å; P574-C577 PolarHBondContact O-SG 3.34Å; P574-L597 HydrophobicContact CG-CD2 4.3Å
575V93.4Very high92.6Very high0 Ų029.5 Ų29.50%016%0.162CC..G310 helixtrans-75.3-10.1180-630000113.3Y48 R128 F568 F572 G573 C577 L578 F583Y48-V575 HydrophobicContact CD1-CG1 3.89Å; Y48-V575 HydrophobicContact CD2-CG1 3.87Å; Y48-V575 HydrophobicContact CE1-CG1 4.25Å; Y48-V575 HydrophobicContact CE2-CG1 4.22Å; Y48-V575 HydrophobicContact CG-CG1 3.69Å; R128-V575 PolarHBondContact NH2-O 3.16Å; F568-V575 HydrophobicContact CE1-CB 4.42Å; F568-V575 HydrophobicContact CE1-CG1 3.77Å; F568-V575 HydrophobicContact CE1-CG2 3.74Å; F568-V575 HydrophobicContact CZ-CG1 4.11Å; F568-V575 HydrophobicContact CZ-CG2 4.28Å; F572-V575 HydrophobicContact CB-CG1 4.33Å; G573-V575 PolarHBondContact O-N 3.49Å; V575-C577 PolarHBondContact O-N 3.42Å; V575-L578 HydrophobicContact CB-CD1 4.35Å; V575-L578 WeakPolarHBondContact O-CB 3.48Å; V575-L578 PolarHBondContact O-N 2.97Å; V575-L578 VanDerWaalsContact O-N 3.15Å; V575-F583 HydrophobicContact CB-CD2 4.15Å; V575-F583 HydrophobicContact CB-CE2 4.19Å; V575-F583 HydrophobicContact CG2-CD2 4.24Å; V575-F583 HydrophobicContact CG2-CE2 3.82Å
576D91.5Very high92.5Very high28 Ų2828.7 Ų28.715%0.1516%0.158CC..G310 helixtrans-62.1-22.8175.956.5-51.3000113.3R128 E166 K170 P574 L578R128-D576 PolarHBondContact NH2-O 2.89Å; E166-D576 HydrophobicContact CB-CB 4.45Å; E166-D576 HydrophobicContact CG-CB 3.96Å; K170-D576 IonicContact NZ-OD2 3.34Å; K170-D576 PolarHBondContact NZ-OD2 3.36Å; P574-D576 VanDerWaalsContact C-OD1 3.24Å; P574-D576 WeakPolarHBondContact CA-OD1 3.4Å; P574-D576 VanDerWaalsContact CB-OD1 3.23Å; P574-D576 WeakPolarHBondContact CB-OD1 3.41Å; P574-D576 PolarHBondContact O-N 3.39Å; D576-L578 VanDerWaalsContact C-N 3.34Å
577C91.6Very high92.5Very high27 Ų2727.2 Ų27.218%0.18215%0.153CC..G310 helixtrans-80.8-10.9176.369.80000114.3P574 V575 V595 E596P574-C577 PolarHBondContact O-SG 3.34Å; V575-C577 PolarHBondContact O-N 3.42Å; C577-V595 HydrophobicContact CB-CG1 4.06Å; C577-V595 WeakPolarHBondContact SG-CG1 3.34Å; C577-E596 WeakPolarHBondContact CB-O 3.36Å
578L94.4Very high92.6Very high0 Ų028.5 Ų28.50%016%0.157CC..SBendtrans-77.6147178.2-61.5176.6000110.4L45 Y48 L49 R128 V575 D576 L582 F583 V595L45-L578 HydrophobicContact CD2-CD1 4.3Å; L45-L578 HydrophobicContact CD2-CD2 4.29Å; L45-L578 HydrophobicContact CD2-CG 4.23Å; Y48-L578 HydrophobicContact CD1-CD1 3.5Å; Y48-L578 HydrophobicContact CE1-CD1 3.73Å; L49-L578 HydrophobicContact CD2-CD1 4.23Å; L49-L578 HydrophobicContact CD2-CD2 4.34Å; R128-L578 VanDerWaalsContact CZ-O 3.31Å; R128-L578 PolarHBondContact NH1-O 2.94Å; R128-L578 PolarHBondContact NH2-O 3.12Å; V575-L578 HydrophobicContact CB-CD1 4.35Å; V575-L578 WeakPolarHBondContact O-CB 3.48Å; V575-L578 PolarHBondContact O-N 2.97Å; V575-L578 VanDerWaalsContact O-N 3.15Å; D576-L578 VanDerWaalsContact C-N 3.34Å; L578-L582 HydrophobicContact CB-CB 4.47Å; L578-F583 HydrophobicContact CB-CB 4.48Å; L578-V595 HydrophobicContact CD2-CG1 4.19Å; L578-V595 HydrophobicContact CD2-CG2 3.86Å
579S94.5Very high92.6Very high22 Ų2231.8 Ų31.815%0.15418%0.175CC..  trans-63.2152.8166.975.50000110.7R581 L582 F583S579-R581 VanDerWaalsContact C-N 3.28Å; S579-R581 PolarHBondContact O-N 2.97Å; S579-L582 PolarHBondContact O-N 3.34Å; S579-L582 VanDerWaalsContact O-N 3.08Å; S579-L582 WeakPolarHBondContact OG-CD1 3.41Å; S579-L582 WeakPolarHBondContact OG-CG 3.38Å; S579-L582 PolarHBondContact OG-N 2.89Å; S579-F583 PolarHBondContact O-N 3.19Å
580T95.9Very high92.8Very high1 Ų133.3 Ų33.31%0.00619%0.191CC..Hα-helixtrans-60.7-36.9-175.6-64.10000112.7R128 D131 L389 Y390 F583 L584R128-T580 VanDerWaalsContact NH1-CA 3.26Å; R128-T580 PolarHBondContact NH1-OG1 3.33Å; R128-T580 VanDerWaalsContact NH1-OG1 3.09Å; D131-T580 WeakPolarHBondContact OD2-CB 3.37Å; D131-T580 PolarHBondContact OD2-OG1 3.3Å; L389-T580 HydrophobicContact CB-CG2 3.97Å; Y390-T580 HydrophobicContact CD1-CG2 4.36Å; Y390-T580 HydrophobicContact CE1-CG2 3.65Å; Y390-T580 HydrophobicContact CE2-CG2 4.08Å; Y390-T580 VanDerWaalsContact CZ-CG2 3.5Å; Y390-T580 PolarHBondContact OH-OG1 3.21Å; T580-F583 PolarHBondContact O-N 2.91Å; T580-L584 HydrophobicContact CG2-CD1 3.86Å; T580-L584 HydrophobicContact CG2-CG 4.44Å; T580-L584 WeakPolarHBondContact O-CB 3.5Å; T580-L584 WeakPolarHBondContact O-CG 3.29Å; T580-L584 PolarHBondContact O-N 2.91Å
581R94.9Very high93Very high22 Ų2231.9 Ų31.98%0.08318%0.176CC..Hα-helixtrans-62.6-46.9172.8-175.9-166.759.284.81.1111.9L389 S579 F583 L584 D585 G586 E591L389-R581 HydrophobicContact CD2-CB 4.46Å; S579-R581 VanDerWaalsContact C-N 3.28Å; S579-R581 PolarHBondContact O-N 2.97Å; R581-F583 VanDerWaalsContact C-N 3.27Å; R581-F583 PolarHBondContact O-N 3.34Å; R581-L584 PolarHBondContact O-N 3.2Å; R581-D585 PolarHBondContact O-N 3.44Å; R581-G586 PolarHBondContact NH1-O 3.36Å; R581-G586 PolarHBondContact O-N 3.48Å; R581-E591 IonicContact CZ-OE1 2.58Å; R581-E591 IonicContact CZ-OE2 3.04Å; R581-E591 IonicContact NH1-OE1 3.44Å; R581-E591 PolarHBondContact NH1-OE1 3Å; R581-E591 IonicContact NH1-OE2 3.77Å; R581-E591 PolarHBondContact NH1-OE2 3.33Å; R581-E591 IonicContact NH2-OE1 3.64Å; R581-E591 PolarHBondContact NH2-OE1 2.82Å; R581-E591 IonicContact NH2-OE2 3.05Å
582L94.9Very high93.2Very high4 Ų433.2 Ų33.22%0.02118%0.179CC..Hα-helixtrans-65.4-33.6178.5-70173.1000111.9L49 L578 S579 G586 P587 F593L49-L582 HydrophobicContact CD2-CB 4.39Å; L578-L582 HydrophobicContact CB-CB 4.47Å; S579-L582 PolarHBondContact O-N 3.34Å; S579-L582 VanDerWaalsContact O-N 3.08Å; S579-L582 WeakPolarHBondContact OG-CD1 3.41Å; S579-L582 WeakPolarHBondContact OG-CG 3.38Å; S579-L582 PolarHBondContact OG-N 2.89Å; L582-G586 VanDerWaalsContact O-CA 3.28Å; L582-G586 WeakPolarHBondContact O-CA 3.43Å; L582-G586 PolarHBondContact O-N 3.48Å; L582-P587 HydrophobicContact CD2-CB 3.91Å; L582-F593 HydrophobicContact CD1-CB 4.24Å; L582-F593 HydrophobicContact CD1-CD1 4.44Å; L582-F593 HydrophobicContact CD1-CD2 3.36Å; L582-F593 HydrophobicContact CD1-CE2 3.72Å; L582-F593 HydrophobicContact CD1-CG 3.76Å; L582-F593 HydrophobicContact CD1-CZ 4.41Å; L582-F593 HydrophobicContact CD2-CD1 4.24Å; L582-F593 HydrophobicContact CD2-CD2 4.47Å; L582-F593 HydrophobicContact CD2-CE1 4.25Å; L582-F593 HydrophobicContact CD2-CE2 4.45Å; L582-F593 HydrophobicContact CD2-CG 4.35Å; L582-F593 HydrophobicContact CD2-CZ 4.34Å
583F95.6Very high93.3Very high0 Ų033.1 Ų33.10%018%0.179CC..Hα-helixtrans-65.8-40.3175177.3-98.8000112.5Y48 T59 L164 V575 L578 S579 T580 R581Y48-F583 AromaticContact CE1-CD2 3.92Å; Y48-F583 HydrophobicContact CE1-CD2 3.92Å; Y48-F583 HydrophobicContact CE1-CE2 4.45Å; Y48-F583 AromaticContact CZ-CD2 3.75Å; Y48-F583 AromaticContact CZ-CE2 3.84Å; Y48-F583 VanDerWaalsContact OH-CD2 3.24Å; Y48-F583 WeakPolarHBondContact OH-CD2 3.48Å; Y48-F583 VanDerWaalsContact OH-CE2 3.22Å; Y48-F583 WeakPolarHBondContact OH-CE2 3.35Å; Y48-F583 PolarHBondContact OH-O 3.41Å; T59-F583 WeakPolarHBondContact OG1-CE1 3.28Å; L164-F583 WeakPolarHBondContact O-CE2 3.42Å; L164-F583 WeakPolarHBondContact O-CZ 2.96Å; V575-F583 HydrophobicContact CB-CD2 4.15Å; V575-F583 HydrophobicContact CB-CE2 4.19Å; V575-F583 HydrophobicContact CG2-CD2 4.24Å; V575-F583 HydrophobicContact CG2-CE2 3.82Å; L578-F583 HydrophobicContact CB-CB 4.48Å; S579-F583 PolarHBondContact O-N 3.19Å; T580-F583 PolarHBondContact O-N 2.91Å; R581-F583 VanDerWaalsContact C-N 3.27Å; R581-F583 PolarHBondContact O-N 3.34Å
584L94.6Very high93.7Very high4 Ų439.3 Ų39.32%0.02121%0.206CC..Hα-helixtrans-94.5-37.5-173.3-66176.9000115.2P57 P67 F393 T580 R581P57-L584 VanDerWaalsContact CB-O 3.25Å; P57-L584 WeakPolarHBondContact CB-O 3.41Å; P57-L584 WeakPolarHBondContact CD-O 3.49Å; P57-L584 WeakPolarHBondContact CG-O 3.36Å; P67-L584 HydrophobicContact CG-CB 3.77Å; P67-L584 HydrophobicContact CG-CD1 4.04Å; F393-L584 HydrophobicContact CE2-CD1 3.87Å; F393-L584 HydrophobicContact CE2-CD2 3.85Å; F393-L584 HydrophobicContact CZ-CD2 3.97Å; T580-L584 HydrophobicContact CG2-CD1 3.86Å; T580-L584 HydrophobicContact CG2-CG 4.44Å; T580-L584 WeakPolarHBondContact O-CB 3.5Å; T580-L584 WeakPolarHBondContact O-CG 3.29Å; T580-L584 PolarHBondContact O-N 2.91Å; R581-L584 PolarHBondContact O-N 3.2Å
585D92.7Very high93.9Very high60 Ų6037.6 Ų37.632%0.32120%0.195SC..THydrogen-bonded Turntrans-115.5-11.8-174.5-159.542.4000112.3P67 R581P67-D585 HydrophobicContact CG-CB 4.34Å; R581-D585 PolarHBondContact O-N 3.44Å
586G93.5Very high93.7Very high1 Ų143 Ų431%0.0122%0.221CC..  trans68.5-179-174.900000112.7R581 L582R581-G586 PolarHBondContact NH1-O 3.36Å; R581-G586 PolarHBondContact O-N 3.48Å; L582-G586 VanDerWaalsContact O-CA 3.28Å; L582-G586 WeakPolarHBondContact O-CA 3.43Å; L582-G586 PolarHBondContact O-N 3.48Å
587P94.7Very high93.4Very high7 Ų743.4 Ų43.45%0.04522%0.223CC..PPolyproline II helixtrans-83.9148.5176.932.7-32.2000111.7L49 M53 L582 E591 F593 A607 F623L49-P587 HydrophobicContact CB-CG 4.45Å; L49-P587 HydrophobicContact CD2-CG 4.35Å; M53-P587 HydrophobicContact CG-CG 4.24Å; M53-P587 HydrophobicContact SD-CG 3.82Å; L582-P587 HydrophobicContact CD2-CB 3.91Å; P587-E591 VanDerWaalsContact CA-OE2 3.31Å; P587-E591 WeakPolarHBondContact CA-OE2 3.19Å; P587-F593 HydrophobicContact CB-CD1 4.23Å; P587-F593 HydrophobicContact CB-CE1 3.48Å; P587-F593 VanDerWaalsContact CB-CE1 3.48Å; P587-F593 HydrophobicContact CB-CZ 4.12Å; P587-F593 HydrophobicContact CG-CE1 4.05Å; P587-F593 HydrophobicContact CG-CZ 4.26Å; P587-A607 HydrophobicContact CB-CB 4.04Å; P587-A607 HydrophobicContact CG-CB 3.92Å; P587-F623 HydrophobicContact CG-CE1 4.24Å
588K93.7Very high92.8Very high127 Ų12745.5 Ų45.555%0.55223%0.229SC*.PPolyproline II helixtrans-78.6156.8169.2-64.1175.2-176.3170.40110.3A590 E591K588-A590 PolarHBondContact O-N 2.89Å; K588-E591 HydrophobicContact CB-CB 4.15Å; K588-E591 PolarHBondContact N-OE2 2.87Å; K588-E591 WeakPolarHBondContact O-CB 3.44Å; K588-E591 PolarHBondContact O-N 3.39Å
589I95.1Very high91.9Very high96 Ų9657.1 Ų57.149%0.49227%0.273SS..THydrogen-bonded Turntrans-60.2136171.9-60.7-58.8000109.7M53 E591 L608M53-I589 HydrophobicContact CE-CD1 3.55Å; I589-E591 PolarHBondContact O-N 2.82Å; I589-L608 WeakPolarHBondContact CG2-O 3.46Å
590A93.6Very high91.2Very high67 Ų6759.5 Ų59.555%0.55430%0.302SS*.THydrogen-bonded Turntrans66.46.6-172.500000115.7K588 A607K588-A590 PolarHBondContact O-N 2.89Å; A590-A607 WeakPolarHBondContact CA-O 3.47Å; A590-A607 PolarHBondContact N-O 3.19Å
591E94Very high90.7Very high44 Ų4464.9 Ų64.921%0.20633%0.325CS..  trans-75.2132.2172.9-173.6172-164.400111.1R581 P587 K588 I589 F593 K606 A607R581-E591 IonicContact CZ-OE1 2.58Å; R581-E591 IonicContact CZ-OE2 3.04Å; R581-E591 IonicContact NH1-OE1 3.44Å; R581-E591 PolarHBondContact NH1-OE1 3Å; R581-E591 IonicContact NH1-OE2 3.77Å; R581-E591 PolarHBondContact NH1-OE2 3.33Å; R581-E591 IonicContact NH2-OE1 3.64Å; R581-E591 PolarHBondContact NH2-OE1 2.82Å; R581-E591 IonicContact NH2-OE2 3.05Å; P587-E591 VanDerWaalsContact CA-OE2 3.31Å; P587-E591 WeakPolarHBondContact CA-OE2 3.19Å; K588-E591 HydrophobicContact CB-CB 4.15Å; K588-E591 PolarHBondContact N-OE2 2.87Å; K588-E591 WeakPolarHBondContact O-CB 3.44Å; K588-E591 PolarHBondContact O-N 3.39Å; I589-E591 PolarHBondContact O-N 2.82Å; E591-F593 HydrophobicContact CG-CD1 4.37Å; E591-K606 VanDerWaalsContact O-CA 3.3Å; E591-K606 WeakPolarHBondContact O-CA 3.46Å; E591-A607 PolarHBondContact O-N 3.38Å; E591-A607 VanDerWaalsContact O-N 3.12Å
592E94.3Very high90.5Very high123 Ų12366.3 Ų66.358%0.57534%0.336SS*.EExtended strand (participates in β ladder)trans-113137.1175.6-176.2171.7-179.600109.7I605 K606E592-I605 WeakPolarHBondContact CA-O 3.2Å; E592-K606 HydrophobicContact CB-CB 4.4Å; E592-K606 HydrophobicContact CB-CG 4.33Å
593F94.1Very high90.4Very high21 Ų2166.9 Ų66.99%0.09234%0.339CS..EExtended strand (participates in β ladder)trans-154.8161.1-177.157.2-85.2000111.7L49 L582 P587 E591 V595 I605L49-F593 HydrophobicContact CD1-CE2 4.05Å; L49-F593 HydrophobicContact CD1-CZ 3.77Å; L49-F593 HydrophobicContact CD2-CZ 4.35Å; L582-F593 HydrophobicContact CD1-CB 4.24Å; L582-F593 HydrophobicContact CD1-CD1 4.44Å; L582-F593 HydrophobicContact CD1-CD2 3.36Å; L582-F593 HydrophobicContact CD1-CE2 3.72Å; L582-F593 HydrophobicContact CD1-CG 3.76Å; L582-F593 HydrophobicContact CD1-CZ 4.41Å; L582-F593 HydrophobicContact CD2-CD1 4.24Å; L582-F593 HydrophobicContact CD2-CD2 4.47Å; L582-F593 HydrophobicContact CD2-CE1 4.25Å; L582-F593 HydrophobicContact CD2-CE2 4.45Å; L582-F593 HydrophobicContact CD2-CG 4.35Å; L582-F593 HydrophobicContact CD2-CZ 4.34Å; P587-F593 HydrophobicContact CB-CD1 4.23Å; P587-F593 HydrophobicContact CB-CE1 3.48Å; P587-F593 VanDerWaalsContact CB-CE1 3.48Å; P587-F593 HydrophobicContact CB-CZ 4.12Å; P587-F593 HydrophobicContact CG-CE1 4.05Å; P587-F593 HydrophobicContact CG-CZ 4.26Å; E591-F593 HydrophobicContact CG-CD1 4.37Å; F593-V595 HydrophobicContact CD2-CG2 3.82Å; F593-V595 HydrophobicContact CE2-CG2 3.83Å; F593-I605 HydrophobicContact CD2-CB 4.33Å; F593-I605 HydrophobicContact CE1-CB 4.2Å; F593-I605 HydrophobicContact CE1-CG2 3.96Å; F593-I605 HydrophobicContact CE2-CB 3.76Å; F593-I605 HydrophobicContact CE2-CD1 4.04Å; F593-I605 HydrophobicContact CE2-CG1 4.45Å; F593-I605 HydrophobicContact CE2-CG2 4.03Å; F593-I605 HydrophobicContact CZ-CB 3.69Å; F593-I605 HydrophobicContact CZ-CD1 4.47Å; F593-I605 HydrophobicContact CZ-CG2 3.46Å; F593-I605 VanDerWaalsContact CZ-CG2 3.46Å; F593-I605 PolarHBondContact N-O 3.23Å; F593-I605 PolarHBondContact O-N 3.06Å
594E93.8Very high90.3Very high134 Ų13470.5 Ų70.563%0.62636%0.356SS*.EExtended strand (participates in β ladder)trans-107.7139.9-179.8-64.4-174.6177.800111.2T602 L603 H604E594-T602 HydrophobicContact CB-CG2 3.82Å; E594-T602 HydrophobicContact CG-CG2 4.18Å; E594-L603 WeakPolarHBondContact CA-O 3.2Å; E594-H604 IonicContact OE1-CE1 3.91Å; E594-H604 PolarHBondContact OE1-CE1 3.44Å; E594-H604 IonicContact OE1-ND1 3.98Å; E594-H604 PolarHBondContact OE1-ND1 3.36Å
595V92.1Very high90.4Very high2 Ų270.3 Ų70.31%0.01236%0.355CS..EExtended strand (participates in β ladder)trans-129114.7173.9-177.10000109.2L45 C577 L578 F593 T602 L603 I605L45-V595 HydrophobicContact CD1-CG1 4.15Å; C577-V595 HydrophobicContact CB-CG1 4.06Å; C577-V595 WeakPolarHBondContact SG-CG1 3.34Å; L578-V595 HydrophobicContact CD2-CG1 4.19Å; L578-V595 HydrophobicContact CD2-CG2 3.86Å; F593-V595 HydrophobicContact CD2-CG2 3.82Å; F593-V595 HydrophobicContact CE2-CG2 3.83Å; V595-T602 WeakPolarHBondContact O-CA 3.42Å; V595-L603 HydrophobicContact CB-CB 4.38Å; V595-L603 PolarHBondContact N-O 2.81Å; V595-L603 PolarHBondContact O-N 3.13Å; V595-I605 HydrophobicContact CG2-CD1 4.14Å
596E89Confident90.6Very high113 Ų11370.5 Ų70.553%0.52835%0.353SS..EExtended strand (participates in β ladder)trans-84.6112.9174-170.8177.8179.600109.8C577 R599C577-E596 WeakPolarHBondContact CB-O 3.36Å; E596-R599 WeakPolarHBondContact OE1-CA 3.47Å
597L83.8Confident90.7Very high37 Ų3770.4 Ų70.419%0.19435%0.352CS..EExtended strand (participates in β ladder)trans-81-40.2178.2-77.4179.7000112.4R41 L45 P574 K601 L603R41-L597 HydrophobicContact CB-CD1 4.25Å; L45-L597 HydrophobicContact CD1-CD2 3.58Å; P574-L597 HydrophobicContact CG-CD2 4.3Å; L597-K601 PolarHBondContact N-O 3.3Å; L597-L603 HydrophobicContact CD1-CD1 3.86Å; L597-L603 HydrophobicContact CD1-CD2 4.12Å; L597-L603 HydrophobicContact CD1-CG 4.05Å; L597-L603 HydrophobicContact CG-CD1 4.05Å; L597-L603 HydrophobicContact CG-CG 4.18Å
598E79.1Confident90.7Very high70 Ų7072.9 Ų72.933%0.32737%0.365SS..EExtended strand (participates in β ladder)trans-159.7161.9178.258.3-162.6164.600107.9R41 G600 K601R41-E598 IonicContact CZ-OE1 2.99Å; R41-E598 IonicContact NH1-OE1 3.8Å; R41-E598 IonicContact NH1-OE2 3.77Å; R41-E598 PolarHBondContact NH1-OE2 2.79Å; R41-E598 IonicContact NH2-OE1 3.16Å; R41-E598 PolarHBondContact NH2-OE1 3.46Å; R41-E598 IonicContact NH2-OE2 3.75Å; E598-G600 PolarHBondContact O-N 3.21Å; E598-K601 HydrophobicContact CG-CB 3.87Å; E598-K601 HydrophobicContact CG-CD 3.83Å; E598-K601 HydrophobicContact CG-CG 3.86Å; E598-K601 PolarHBondContact O-N 3.49Å; E598-K601 WeakPolarHBondContact OE1-CD 3.19Å; E598-K601 WeakPolarHBondContact OE1-CE 3.4Å; E598-K601 IonicContact OE1-NZ 2.76Å; E598-K601 PolarHBondContact OE1-NZ 3.17Å
599R76.7Confident90.7Very high244 Ų24468.8 Ų68.892%0.92136%0.355SS*.THydrogen-bonded Turntrans-50.7118.6-176-171.8177.2179.6178.60.9111.1E596E596-R599 WeakPolarHBondContact OE1-CA 3.47Å
600G79.5Confident90.7Very high73 Ų7367.6 Ų67.675%0.75335%0.349SS*.THydrogen-bonded Turntrans827.218000000115.7E598E598-G600 PolarHBondContact O-N 3.21Å
601K85.8Confident90.5Very high113 Ų11365.3 Ų65.349%0.49133%0.332SS..EExtended strand (participates in β ladder)trans-121.893171.9-60-163.2-161.4164.40111.2L597 E598L597-K601 PolarHBondContact N-O 3.3Å; E598-K601 HydrophobicContact CG-CB 3.87Å; E598-K601 HydrophobicContact CG-CD 3.83Å; E598-K601 HydrophobicContact CG-CG 3.86Å; E598-K601 PolarHBondContact O-N 3.49Å; E598-K601 WeakPolarHBondContact OE1-CD 3.19Å; E598-K601 WeakPolarHBondContact OE1-CE 3.4Å; E598-K601 IonicContact OE1-NZ 2.76Å; E598-K601 PolarHBondContact OE1-NZ 3.17Å
602T90.8Very high90.4Very high52 Ų5270.3 Ų70.332%0.31936%0.36SS..EExtended strand (participates in β ladder)trans-101136.1176.8-52.90000110.6E594 V595E594-T602 HydrophobicContact CB-CG2 3.82Å; E594-T602 HydrophobicContact CG-CG2 4.18Å; V595-T602 WeakPolarHBondContact O-CA 3.42Å
603L91.8Very high90.2Very high16 Ų1667.6 Ų67.68%0.08435%0.349CS..EExtended strand (participates in β ladder)trans-99.5124.2170.1-53.4-176.7000108.8A42 L45 E594 V595 L597 I605 L625A42-L603 HydrophobicContact CB-CD1 3.83Å; A42-L603 HydrophobicContact CB-CD2 4.34Å; L45-L603 HydrophobicContact CD1-CD1 4.16Å; E594-L603 WeakPolarHBondContact CA-O 3.2Å; V595-L603 HydrophobicContact CB-CB 4.38Å; V595-L603 PolarHBondContact N-O 2.81Å; V595-L603 PolarHBondContact O-N 3.13Å; L597-L603 HydrophobicContact CD1-CD1 3.86Å; L597-L603 HydrophobicContact CD1-CD2 4.12Å; L597-L603 HydrophobicContact CD1-CG 4.05Å; L597-L603 HydrophobicContact CG-CD1 4.05Å; L597-L603 HydrophobicContact CG-CG 4.18Å; L603-I605 HydrophobicContact CB-CD1 4.08Å; L603-I605 HydrophobicContact CB-CG1 4.1Å; L603-I605 HydrophobicContact CD1-CD1 4.29Å; L603-L625 HydrophobicContact CB-CD1 3.92Å; L603-L625 HydrophobicContact CD1-CD1 4.31Å; L603-L625 HydrophobicContact CD2-CD1 4.23Å; L603-L625 HydrophobicContact CG-CD1 4.38Å
604H94.6Very high89.9Confident76 Ų7669.5 Ų69.535%0.35236%0.36SS..EExtended strand (participates in β ladder)trans-92.6112.7167.4-59-86000107.8E594 L625 N626E594-H604 IonicContact OE1-CE1 3.91Å; E594-H604 PolarHBondContact OE1-CE1 3.44Å; E594-H604 IonicContact OE1-ND1 3.98Å; E594-H604 PolarHBondContact OE1-ND1 3.36Å; H604-L625 WeakPolarHBondContact O-CA 3.25Å; H604-N626 PolarHBondContact N-OD1 3.42Å; H604-N626 PolarHBondContact O-N 2.78Å
605I95.9Very high89.3Confident0 Ų073 Ų730%037%0.373CS..EExtended strand (participates in β ladder)trans-119.4134.3-175-60.6168000109.1L46 L49 E592 F593 V595 L603 F623 E624 L625L46-I605 HydrophobicContact CD2-CD1 4.02Å; L46-I605 HydrophobicContact CD2-CG1 4.22Å; L46-I605 HydrophobicContact CD2-CG2 3.71Å; L49-I605 HydrophobicContact CD1-CD1 4.29Å; E592-I605 WeakPolarHBondContact CA-O 3.2Å; F593-I605 HydrophobicContact CD2-CB 4.33Å; F593-I605 HydrophobicContact CE1-CB 4.2Å; F593-I605 HydrophobicContact CE1-CG2 3.96Å; F593-I605 HydrophobicContact CE2-CB 3.76Å; F593-I605 HydrophobicContact CE2-CD1 4.04Å; F593-I605 HydrophobicContact CE2-CG1 4.45Å; F593-I605 HydrophobicContact CE2-CG2 4.03Å; F593-I605 HydrophobicContact CZ-CB 3.69Å; F593-I605 HydrophobicContact CZ-CD1 4.47Å; F593-I605 HydrophobicContact CZ-CG2 3.46Å; F593-I605 VanDerWaalsContact CZ-CG2 3.46Å; F593-I605 PolarHBondContact N-O 3.23Å; F593-I605 PolarHBondContact O-N 3.06Å; V595-I605 HydrophobicContact CG2-CD1 4.14Å; L603-I605 HydrophobicContact CB-CD1 4.08Å; L603-I605 HydrophobicContact CB-CG1 4.1Å; L603-I605 HydrophobicContact CD1-CD1 4.29Å; I605-F623 HydrophobicContact CG2-CD1 3.91Å; I605-E624 CarbonylContact C-O 3.54Å; I605-E624 VanDerWaalsContact CA-O 3.31Å; I605-E624 WeakPolarHBondContact CA-O 3.3Å; I605-L625 HydrophobicContact CD1-CD1 4.29Å; I605-L625 HydrophobicContact CG1-CD1 3.63Å
606K96.7Very high88.8Confident64 Ų6474.7 Ų74.728%0.27839%0.392SS..EExtended strand (participates in β ladder)trans-127.4126.6171.1-173.2176.4-176.11670110.9E591 E592 L608 F623 E624E591-K606 VanDerWaalsContact O-CA 3.3Å; E591-K606 WeakPolarHBondContact O-CA 3.46Å; E592-K606 HydrophobicContact CB-CB 4.4Å; E592-K606 HydrophobicContact CB-CG 4.33Å; K606-L608 HydrophobicContact CD-CD2 4.09Å; K606-L608 HydrophobicContact CG-CD2 4.13Å; K606-F623 CarbonylContact O-C 3.49Å; K606-F623 VanDerWaalsContact O-CA 3.23Å; K606-F623 WeakPolarHBondContact O-CA 3.31Å; K606-E624 HydrophobicContact CB-CB 4.06Å; K606-E624 PolarHBondContact N-O 2.99Å; K606-E624 PolarHBondContact O-N 2.97Å
607A95.6Very high88.6Confident0 Ų069.3 Ų69.30%037%0.366CS..EExtended strand (participates in β ladder)trans-80.1122.2173.600000109.8M53 P587 A590 E591 F623M53-A607 HydrophobicContact CE-CB 4.09Å; M53-A607 HydrophobicContact SD-CB 4.29Å; P587-A607 HydrophobicContact CB-CB 4.04Å; P587-A607 HydrophobicContact CG-CB 3.92Å; A590-A607 WeakPolarHBondContact CA-O 3.47Å; A590-A607 PolarHBondContact N-O 3.19Å; E591-A607 PolarHBondContact O-N 3.38Å; E591-A607 VanDerWaalsContact O-N 3.12Å; A607-F623 HydrophobicContact CB-CD1 4.11Å; A607-F623 HydrophobicContact CB-CE1 3.93Å
608L95.4Very high89Confident58 Ų5870.8 Ų70.830%0.30437%0.372SS..EExtended strand (participates in β ladder)trans-101.4-49.8-170.9-63.1175.5000113.1I589 K606 F622 E624 L629I589-L608 WeakPolarHBondContact CG2-O 3.46Å; K606-L608 HydrophobicContact CD-CD2 4.09Å; K606-L608 HydrophobicContact CG-CD2 4.13Å; L608-F622 HydrophobicContact CB-CB 4.12Å; L608-F622 WeakPolarHBondContact CB-O 3.27Å; L608-F622 PolarHBondContact N-O 3.13Å; L608-E624 HydrophobicContact CD1-CB 4.19Å; L608-E624 HydrophobicContact CD2-CB 4.46Å; L608-E624 HydrophobicContact CG-CB 4.43Å; L608-L629 HydrophobicContact CD1-CD1 3.32Å
609A94.1Very high89.7Confident41 Ų4170.4 Ų70.434%0.33937%0.368SS..EExtended strand (participates in β ladder)trans-160.4154-174.900000111.7F622A609-F622 HydrophobicContact CB-CB 4.4Å; A609-F622 HydrophobicContact CB-CD2 4.08Å; A609-F622 PolarHBondContact N-O 3.44Å; A609-F622 PolarHBondContact O-N 2.84Å
610L93.8Very high90.6Very high72 Ų7262 Ų6238%0.37734%0.339SS..EExtended strand (participates in β ladder)trans-111.7119.5167.8-176.669.8000109.1V54 R619 V621V54-L610 HydrophobicContact CG2-CD1 3.54Å; L610-R619 HydrophobicContact CD1-CB 4.23Å; L610-V621 HydrophobicContact CD1-CB 4.37Å; L610-V621 HydrophobicContact CD1-CG1 4.27Å; L610-V621 HydrophobicContact CD1-CG2 3.67Å
611G90.4Very high91.4Very high18 Ų1858.6 Ų58.619%0.18630%0.303CS..EExtended strand (participates in β ladder)trans-75.5165.5178.800000113.8R619 E620G611-R619 PolarHBondContact O-NH1 3.17Å; G611-E620 WeakPolarHBondContact CA-O 3.48Å; G611-E620 PolarHBondContact N-O 3.49Å
612D91.5Very high91.9Very high149 Ų14956 Ų5680%0.79729%0.292SS*.EExtended strand (participates in β ladder)trans-67.3160.8175.5-69.9-41.9000112.6N614D612-N614 PolarHBondContact O-N 3.06Å
613L90Very high92.2Very high66 Ų6653.5 Ų53.535%0.34628%0.277SS..EExtended strand (participates in β ladder)trans-68.2120.2175.6-171.872.3000110.1G617 R619 D636 A639L613-G617 VanDerWaalsContact CD1-C 3.47Å; L613-R619 HydrophobicContact CD1-CG 4.14Å; L613-D636 HydrophobicContact CD1-CB 3.67Å; L613-A639 HydrophobicContact CD1-CB 4.12Å; L613-A639 HydrophobicContact CD2-CB 3.63Å
614N88.2Confident92.4Very high62 Ų6256.3 Ų56.333%0.33229%0.29SS..PPolyproline II helixtrans-80.2168.5175.67718.9000112D612 G616 G617 Q618D612-N614 PolarHBondContact O-N 3.06Å; N614-G616 PolarHBondContact O-N 2.82Å; N614-G616 VanDerWaalsContact OD1-CA 3.25Å; N614-G616 WeakPolarHBondContact OD1-CA 3.35Å; N614-G616 PolarHBondContact OD1-N 3.16Å; N614-G617 PolarHBondContact O-N 3.3Å; N614-G617 PolarHBondContact OD1-N 2.96Å; N614-G617 VanDerWaalsContact OD1-N 3.17Å; N614-Q618 WeakPolarHBondContact CB-O 3.31Å; N614-Q618 PolarHBondContact N-O 2.86Å; N614-Q618 PolarHBondContact ND2-O 3.32Å; N614-Q618 PolarHBondContact OD1-N 2.95Å; N614-Q618 PolarHBondContact OD1-O 2.84Å
615K81.5Confident92.4Very high206 Ų20653.5 Ų53.590%0.89628%0.277SS*.THydrogen-bonded Turntrans-59.6-19178.7-65.4-176-178.8178.50114.1G617K615-G617 VanDerWaalsContact C-N 3.33Å
616G80Confident92.2Very high39 Ų3957.6 Ų57.640%0.40230%0.299SS..THydrogen-bonded Turntrans-85.8-0.1175.800000114.2N614N614-G616 PolarHBondContact O-N 2.82Å; N614-G616 VanDerWaalsContact OD1-CA 3.25Å; N614-G616 WeakPolarHBondContact OD1-CA 3.35Å; N614-G616 PolarHBondContact OD1-N 3.16Å
617G86.5Confident91.9Very high0 Ų057.3 Ų57.30%031%0.314CS..SBendtrans76.525.7-176.400000113.2L613 N614 K615 D636L613-G617 VanDerWaalsContact CD1-C 3.47Å; N614-G617 PolarHBondContact O-N 3.3Å; N614-G617 PolarHBondContact OD1-N 2.96Å; N614-G617 VanDerWaalsContact OD1-N 3.17Å; K615-G617 VanDerWaalsContact C-N 3.33Å; G617-D636 PolarHBondContact O-N 2.95Å
618Q91.8Very high91.8Very high68 Ų6862.5 Ų62.532%0.31834%0.338SS..EExtended strand (participates in β ladder)trans-120.3149.4-179.8-53.2175.7-6600110.9N614 V634 K635N614-Q618 WeakPolarHBondContact CB-O 3.31Å; N614-Q618 PolarHBondContact N-O 2.86Å; N614-Q618 PolarHBondContact ND2-O 3.32Å; N614-Q618 PolarHBondContact OD1-N 2.95Å; N614-Q618 PolarHBondContact OD1-O 2.84Å; Q618-V634 CarbonylContact C-O 3.46Å; Q618-V634 WeakPolarHBondContact CA-O 3.5Å; Q618-V634 WeakPolarHBondContact CB-O 3.37Å; Q618-K635 HydrophobicContact CG-CB 4.49Å
619R93.9Very high91.7Very high62 Ų6265.1 Ų65.123%0.23435%0.352CS..EExtended strand (participates in β ladder)trans-110.3141.8171.4-65.7179.1179.4-88.82.1109.4V54 L610 G611 L613 V634 D636V54-R619 HydrophobicContact CG2-CB 4.15Å; L610-R619 HydrophobicContact CD1-CB 4.23Å; G611-R619 PolarHBondContact O-NH1 3.17Å; L613-R619 HydrophobicContact CD1-CG 4.14Å; R619-V634 PolarHBondContact N-O 2.82Å; R619-V634 PolarHBondContact O-N 2.9Å; R619-D636 IonicContact CZ-OD2 3.55Å; R619-D636 IonicContact NE-OD2 3.42Å; R619-D636 PolarHBondContact NE-OD2 2.9Å; R619-D636 IonicContact NH2-OD2 2.82Å
620E95.5Very high91.7Very high68 Ų6867.4 Ų67.432%0.31835%0.352SS..EExtended strand (participates in β ladder)trans-91.4125.8172.5-168.2166.5-158.600109.4G611 F622 S631 V632 L633G611-E620 WeakPolarHBondContact CA-O 3.48Å; G611-E620 PolarHBondContact N-O 3.49Å; E620-F622 HydrophobicContact CB-CE2 4.19Å; E620-F622 HydrophobicContact CB-CZ 4.25Å; E620-F622 HydrophobicContact CG-CE1 4.15Å; E620-F622 HydrophobicContact CG-CE2 4Å; E620-F622 HydrophobicContact CG-CZ 3.71Å; E620-S631 WeakPolarHBondContact OE1-CB 3.37Å; E620-S631 PolarHBondContact OE1-OG 2.82Å; E620-V632 WeakPolarHBondContact CA-O 3.44Å; E620-L633 HydrophobicContact CB-CD2 3.86Å; E620-L633 HydrophobicContact CG-CD2 4.18Å
621V95.9Very high91.7Very high0 Ų066.2 Ų66.20%035%0.35CS..EExtended strand (participates in β ladder)trans-107.8128177.3-161.20000108.6M53 V54 L610 F623 S631 V632 V634M53-V621 HydrophobicContact CE-CG1 4.13Å; M53-V621 HydrophobicContact SD-CG1 3.75Å; V54-V621 HydrophobicContact CG2-CG2 4.04Å; L610-V621 HydrophobicContact CD1-CB 4.37Å; L610-V621 HydrophobicContact CD1-CG1 4.27Å; L610-V621 HydrophobicContact CD1-CG2 3.67Å; V621-F623 HydrophobicContact CB-CE2 3.86Å; V621-F623 HydrophobicContact CB-CZ 4.45Å; V621-F623 HydrophobicContact CG1-CD2 4.35Å; V621-F623 HydrophobicContact CG1-CE2 3.55Å; V621-F623 HydrophobicContact CG1-CZ 3.7Å; V621-S631 CarbonylContact O-C 3.58Å; V621-S631 VanDerWaalsContact O-CA 3.25Å; V621-S631 WeakPolarHBondContact O-CA 3.47Å; V621-V632 HydrophobicContact CB-CG2 3.78Å; V621-V632 HydrophobicContact CG2-CG2 4.17Å; V621-V632 PolarHBondContact N-O 2.94Å; V621-V632 PolarHBondContact O-N 2.77Å; V621-V634 HydrophobicContact CG2-CB 4.29Å; V621-V634 HydrophobicContact CG2-CG2 3.78Å
622F96.7Very high91.8Very high59 Ų5965.7 Ų65.726%0.25934%0.343SS..EExtended strand (participates in β ladder)trans-102.2131.5-177.4-62.2-87.2000110.7L608 A609 E620L608-F622 HydrophobicContact CB-CB 4.12Å; L608-F622 WeakPolarHBondContact CB-O 3.27Å; L608-F622 PolarHBondContact N-O 3.13Å; A609-F622 HydrophobicContact CB-CB 4.4Å; A609-F622 HydrophobicContact CB-CD2 4.08Å; A609-F622 PolarHBondContact N-O 3.44Å; A609-F622 PolarHBondContact O-N 2.84Å; E620-F622 HydrophobicContact CB-CE2 4.19Å; E620-F622 HydrophobicContact CB-CZ 4.25Å; E620-F622 HydrophobicContact CG-CE1 4.15Å; E620-F622 HydrophobicContact CG-CE2 4Å; E620-F622 HydrophobicContact CG-CZ 3.71Å
623F97.1Very high91.9Very high0 Ų062.7 Ų62.70%033%0.327CS..EExtended strand (participates in β ladder)trans-128.4150.8176.6-64.3-85.3000110.5L46 L49 M53 P587 I605 K606 A607 V621 R630 V632L46-F623 HydrophobicContact CB-CD2 4.2Å; L46-F623 HydrophobicContact CB-CE2 4.41Å; L46-F623 HydrophobicContact CD1-CB 4.24Å; L46-F623 HydrophobicContact CD2-CB 3.95Å; L46-F623 HydrophobicContact CD2-CD1 4.02Å; L46-F623 HydrophobicContact CD2-CD2 4.11Å; L46-F623 HydrophobicContact CD2-CG 3.77Å; L49-F623 HydrophobicContact CB-CE1 4.2Å; L49-F623 HydrophobicContact CB-CZ 3.95Å; M53-F623 HydrophobicContact SD-CE1 4.04Å; M53-F623 HydrophobicContact SD-CZ 3.79Å; P587-F623 HydrophobicContact CG-CE1 4.24Å; I605-F623 HydrophobicContact CG2-CD1 3.91Å; K606-F623 CarbonylContact O-C 3.49Å; K606-F623 VanDerWaalsContact O-CA 3.23Å; K606-F623 WeakPolarHBondContact O-CA 3.31Å; A607-F623 HydrophobicContact CB-CD1 4.11Å; A607-F623 HydrophobicContact CB-CE1 3.93Å; V621-F623 HydrophobicContact CB-CE2 3.86Å; V621-F623 HydrophobicContact CB-CZ 4.45Å; V621-F623 HydrophobicContact CG1-CD2 4.35Å; V621-F623 HydrophobicContact CG1-CE2 3.55Å; V621-F623 HydrophobicContact CG1-CZ 3.7Å; F623-R630 PolarHBondContact N-O 2.96Å; F623-R630 PolarHBondContact O-N 2.88Å; F623-V632 HydrophobicContact CD2-CG2 4.17Å; F623-V632 HydrophobicContact CE2-CG2 3.69Å
624E95.9Very high92.1Very high74 Ų7459.6 Ų59.635%0.34631%0.31SS..EExtended strand (participates in β ladder)trans-97.4130157.3-162.5179.6111.900107.9I605 K606 L608I605-E624 CarbonylContact C-O 3.54Å; I605-E624 VanDerWaalsContact CA-O 3.31Å; I605-E624 WeakPolarHBondContact CA-O 3.3Å; K606-E624 HydrophobicContact CB-CB 4.06Å; K606-E624 PolarHBondContact N-O 2.99Å; K606-E624 PolarHBondContact O-N 2.97Å; L608-E624 HydrophobicContact CD1-CB 4.19Å; L608-E624 HydrophobicContact CD2-CB 4.46Å; L608-E624 HydrophobicContact CG-CB 4.43Å
625L93.9Very high92.3Very high18 Ų1862.1 Ų62.19%0.09432%0.318CS..EExtended strand (participates in β ladder)trans-126.4112.8176.4173.469.8000108.4A42 L46 L603 H604 I605 G627 Q628 R630A42-L625 HydrophobicContact CB-CD2 3.77Å; L46-L625 HydrophobicContact CD1-CB 4.36Å; L46-L625 HydrophobicContact CD1-CD2 4.23Å; L603-L625 HydrophobicContact CB-CD1 3.92Å; L603-L625 HydrophobicContact CD1-CD1 4.31Å; L603-L625 HydrophobicContact CD2-CD1 4.23Å; L603-L625 HydrophobicContact CG-CD1 4.38Å; H604-L625 WeakPolarHBondContact O-CA 3.25Å; I605-L625 HydrophobicContact CD1-CD1 4.29Å; I605-L625 HydrophobicContact CG1-CD1 3.63Å; L625-G627 PolarHBondContact O-N 3.04Å; L625-Q628 PolarHBondContact N-O 2.93Å; L625-Q628 WeakPolarHBondContact O-CB 3.15Å; L625-Q628 PolarHBondContact O-N 2.58Å; L625-R630 HydrophobicContact CB-CG 4.08Å; L625-R630 HydrophobicContact CD2-CG 4.42Å
626N92.3Very high92.7Very high86 Ų8652.9 Ų52.946%0.4628%0.279SS..THydrogen-bonded Turntrans49.445.8-176.9-62.3-10.1000112.2H604 Q628H604-N626 PolarHBondContact N-OD1 3.42Å; H604-N626 PolarHBondContact O-N 2.78Å; N626-Q628 VanDerWaalsContact C-N 3.26Å; N626-Q628 PolarHBondContact O-N 3.17Å
627G89.8Confident93.1Very high58 Ų5854 Ų5460%0.59828%0.278SS*.THydrogen-bonded Turntrans75.91.6-178.300000115.5L625L625-G627 PolarHBondContact O-N 3.04Å
628Q92.9Very high92.8Very high108 Ų10858.4 Ų58.451%0.50530%0.304SS..EExtended strand (participates in β ladder)trans-106.5131.3177.4-61.6-170.21.900111.8L625 N626 R630L625-Q628 PolarHBondContact N-O 2.93Å; L625-Q628 WeakPolarHBondContact O-CB 3.15Å; L625-Q628 PolarHBondContact O-N 2.58Å; N626-Q628 VanDerWaalsContact C-N 3.26Å; N626-Q628 PolarHBondContact O-N 3.17Å; Q628-R630 PolarHBondContact O-N 3.04Å
629L94.7Very high92.2Very high114 Ų11456.1 Ų56.160%0.59730%0.297SS*.EExtended strand (participates in β ladder)trans-64.2134172.4-168.970.4000110.5L608L608-L629 HydrophobicContact CD1-CD1 3.32Å
630R93.8Very high91.2Very high89 Ų8954.9 Ų54.934%0.33630%0.295SS..EExtended strand (participates in β ladder)trans-134.4145.9174.5-68.7-66.5-174.2-97.9-1.9108.7L46 F623 L625 Q628L46-R630 HydrophobicContact CD1-CB 3.69Å; L46-R630 HydrophobicContact CD1-CG 4.03Å; F623-R630 PolarHBondContact N-O 2.96Å; F623-R630 PolarHBondContact O-N 2.88Å; L625-R630 HydrophobicContact CB-CG 4.08Å; L625-R630 HydrophobicContact CD2-CG 4.42Å; Q628-R630 PolarHBondContact O-N 3.04Å
631S93.1Very high90.1Very high46 Ų4660.3 Ų60.332%0.32232%0.317SS..EExtended strand (participates in β ladder)trans-126.9152168.370.30000111.1Q43 E620 V621Q43-S631 PolarHBondContact NE2-O 3.37Å; E620-S631 WeakPolarHBondContact OE1-CB 3.37Å; E620-S631 PolarHBondContact OE1-OG 2.82Å; V621-S631 CarbonylContact O-C 3.58Å; V621-S631 VanDerWaalsContact O-CA 3.25Å; V621-S631 WeakPolarHBondContact O-CA 3.47Å
632V93.8Very high88.5Confident7 Ų768.7 Ų68.74%0.04236%0.356CS..EExtended strand (participates in β ladder)trans-130.4132.7173.7-68.60000109.2L46 H47 E620 V621 F623 V634L46-V632 HydrophobicContact CB-CG1 3.98Å; H47-V632 HydrophobicContact CB-CG1 4.42Å; E620-V632 WeakPolarHBondContact CA-O 3.44Å; V621-V632 HydrophobicContact CB-CG2 3.78Å; V621-V632 HydrophobicContact CG2-CG2 4.17Å; V621-V632 PolarHBondContact N-O 2.94Å; V621-V632 PolarHBondContact O-N 2.77Å; F623-V632 HydrophobicContact CD2-CG2 4.17Å; F623-V632 HydrophobicContact CE2-CG2 3.69Å; V632-V634 HydrophobicContact CG2-CG2 4.08Å
633L93Very high86.9Confident87 Ų8768.8 Ų68.846%0.45536%0.358SS..EExtended strand (participates in β ladder)trans-89.7117.7173.1-76.7169000109.4E620E620-L633 HydrophobicContact CB-CD2 3.86Å; E620-L633 HydrophobicContact CG-CD2 4.18Å
634V93.9Very high85Confident0 Ų078.4 Ų78.40%040%0.4CS..EExtended strand (participates in β ladder)trans-115.8130.4-175.2176.70000109.4H51 V54 Q618 R619 V621 V632H51-V634 HydrophobicContact CB-CG1 4.42Å; V54-V634 HydrophobicContact CB-CG1 3.74Å; V54-V634 HydrophobicContact CG1-CG1 4.06Å; V54-V634 HydrophobicContact CG2-CB 4.06Å; V54-V634 HydrophobicContact CG2-CG1 3.84Å; Q618-V634 CarbonylContact C-O 3.46Å; Q618-V634 WeakPolarHBondContact CA-O 3.5Å; Q618-V634 WeakPolarHBondContact CB-O 3.37Å; R619-V634 PolarHBondContact N-O 2.82Å; R619-V634 PolarHBondContact O-N 2.9Å; V621-V634 HydrophobicContact CG2-CB 4.29Å; V621-V634 HydrophobicContact CG2-CG2 3.78Å; V632-V634 HydrophobicContact CG2-CG2 4.08Å
635K91.7Very high83.2Confident115 Ų11579.8 Ų79.850%0.541%0.405SS..EExtended strand (participates in β ladder)trans-72.7126.6176-169.5-180-179.9-175.60110.2N55 Q618 T637 M640N55-K635 PolarHBondContact ND2-O 3.25Å; N55-K635 PolarHBondContact OD1-O 3.36Å; Q618-K635 HydrophobicContact CG-CB 4.49Å; K635-T637 PolarHBondContact O-N 3.32Å; K635-M640 HydrophobicContact CD-CE 4.46Å; K635-M640 HydrophobicContact CD-SD 3.76Å; K635-M640 WeakPolarHBondContact CE-SD 3.5Å; K635-M640 HydrophobicContact CG-SD 3.36Å; K635-M640 WeakPolarHBondContact CG-SD 3.23Å
636D91.4Very high81.9Confident12 Ų1286.8 Ų86.86%0.06444%0.437CS..  trans-87.399.7177-173.7-34.3000109.2V54 L613 G617 R619 V638 A639 M640V54-D636 HydrophobicContact CG1-CB 3.92Å; L613-D636 HydrophobicContact CD1-CB 3.67Å; G617-D636 PolarHBondContact O-N 2.95Å; R619-D636 IonicContact CZ-OD2 3.55Å; R619-D636 IonicContact NE-OD2 3.42Å; R619-D636 PolarHBondContact NE-OD2 2.9Å; R619-D636 IonicContact NH2-OD2 2.82Å; D636-V638 VanDerWaalsContact C-N 3.28Å; D636-V638 PolarHBondContact O-N 3.29Å; D636-V638 PolarHBondContact OD1-N 3.42Å; D636-A639 HydrophobicContact CB-CB 4.06Å; D636-A639 WeakPolarHBondContact OD1-CB 3.39Å; D636-A639 PolarHBondContact OD1-N 3.45Å; D636-M640 VanDerWaalsContact O-CB 3.3Å; D636-M640 WeakPolarHBondContact O-CB 3.19Å; D636-M640 WeakPolarHBondContact O-CG 3.25Å; D636-M640 PolarHBondContact O-N 2.79Å
637T87Confident80.9Confident63 Ų6388.9 Ų88.939%0.38746%0.455SS..THydrogen-bonded Turntrans-69.8-24.8-173.160.70000113.2N55 K635N55-T637 WeakPolarHBondContact OD1-CB 3.33Å; N55-T637 PolarHBondContact OD1-N 3.48Å; N55-T637 PolarHBondContact OD1-OG1 3.46Å; K635-T637 PolarHBondContact O-N 3.32Å
638V81.6Confident80.3Confident92 Ų9295.4 Ų95.456%0.55847%0.467SS*.THydrogen-bonded Turntrans-77.9-52.8178.5179.10000109.4D636 M640 K641D636-V638 VanDerWaalsContact C-N 3.28Å; D636-V638 PolarHBondContact O-N 3.29Å; D636-V638 PolarHBondContact OD1-N 3.42Å; V638-M640 PolarHBondContact O-N 2.83Å; V638-K641 WeakPolarHBondContact O-CB 3.3Å; V638-K641 PolarHBondContact O-N 2.67Å
639A78Confident79.7Confident20 Ų2092 Ų9217%0.16546%0.457CS..Hα-helixtrans-59.8-34.1178.200000111.8L613 D636 K641 E642 M643L613-A639 HydrophobicContact CD1-CB 4.12Å; L613-A639 HydrophobicContact CD2-CB 3.63Å; D636-A639 HydrophobicContact CB-CB 4.06Å; D636-A639 WeakPolarHBondContact OD1-CB 3.39Å; D636-A639 PolarHBondContact OD1-N 3.45Å; A639-K641 VanDerWaalsContact C-N 3.28Å; A639-K641 PolarHBondContact O-N 2.82Å; A639-E642 PolarHBondContact O-N 3.49Å; A639-E642 VanDerWaalsContact O-N 3.17Å; A639-M643 WeakPolarHBondContact O-CG 3.37Å; A639-M643 PolarHBondContact O-N 2.85Å
640M72.7Confident79.1Confident37 Ų3791.7 Ų91.718%0.18245%0.453CS..Hα-helixtrans-67.9-20.1177.7-79.3-163.553.500115.4K635 D636 V638 E642 M643 F645K635-M640 HydrophobicContact CD-CE 4.46Å; K635-M640 HydrophobicContact CD-SD 3.76Å; K635-M640 WeakPolarHBondContact CE-SD 3.5Å; K635-M640 HydrophobicContact CG-SD 3.36Å; K635-M640 WeakPolarHBondContact CG-SD 3.23Å; D636-M640 VanDerWaalsContact O-CB 3.3Å; D636-M640 WeakPolarHBondContact O-CB 3.19Å; D636-M640 WeakPolarHBondContact O-CG 3.25Å; D636-M640 PolarHBondContact O-N 2.79Å; V638-M640 PolarHBondContact O-N 2.83Å; M640-E642 PolarHBondContact O-N 2.89Å; M640-M643 HydrophobicContact CG-SD 4.47Å; M640-M643 PolarHBondContact O-N 2.83Å; M640-F645 HydrophobicContact CB-CE2 4.34Å; M640-F645 HydrophobicContact CE-CD2 3.66Å; M640-F645 HydrophobicContact CE-CE2 3.35Å; M640-F645 HydrophobicContact CE-CG 4.38Å; M640-F645 HydrophobicContact CE-CZ 3.84Å; M640-F645 HydrophobicContact CG-CE2 3.84Å; M640-F645 HydrophobicContact CG-CZ 4.35Å; M640-F645 HydrophobicContact SD-CE2 4.07Å; M640-F645 HydrophobicContact SD-CZ 4.28Å
641K72.2Confident78.1Confident182 Ų18297.9 Ų97.979%0.79148%0.482SS*.Hα-helixtrans-67.7-27.4173-70.3175.7-176.21770112V638 A639V638-K641 WeakPolarHBondContact O-CB 3.3Å; V638-K641 PolarHBondContact O-N 2.67Å; A639-K641 VanDerWaalsContact C-N 3.28Å; A639-K641 PolarHBondContact O-N 2.82Å
642E63.9Low77.2Confident176 Ų176101 Ų10182%0.82250%0.504SS*.Hα-helixtrans-88.2-19178-59.9-174167.500112.3A639 M640A639-E642 PolarHBondContact O-N 3.49Å; A639-E642 VanDerWaalsContact O-N 3.17Å; M640-E642 PolarHBondContact O-N 2.89Å
643M61.6Low76.5Confident61 Ų61104.3 Ų104.330%0.352%0.521SS..SBendtrans-86.4121.9178.6-66.1-178.279.500111.7A639 M640 F645A639-M643 WeakPolarHBondContact O-CG 3.37Å; A639-M643 PolarHBondContact O-N 2.85Å; M640-M643 HydrophobicContact CG-SD 4.47Å; M640-M643 PolarHBondContact O-N 2.83Å; M643-F645 HydrophobicContact CB-CD2 3.91Å; M643-F645 HydrophobicContact CB-CE2 3.4Å; M643-F645 HydrophobicContact CB-CZ 4.2Å; M643-F645 HydrophobicContact CE-CE2 4.24Å; M643-F645 HydrophobicContact CE-CZ 3.84Å; M643-F645 HydrophobicContact CG-CE2 4.3Å; M643-F645 WeakPolarHBondContact O-CD2 3.42Å; M643-F645 PolarHBondContact O-N 2.91Å; M643-F645 VanDerWaalsContact O-N 3.13Å; M643-F645 HydrophobicContact SD-CE2 4.02Å; M643-F645 HydrophobicContact SD-CZ 4.06Å
644K57.6Low75.8Confident202 Ų202110.5 Ų110.588%0.87854%0.544SS*.  trans-75.6100.7172.8-70.9-176.3-179.9178.70110.7
645F59.3Low75.1Confident103 Ų103114.1 Ų114.145%0.45258%0.581SS.*PPolyproline II helixtrans-93.2126.6169.5-71.6-86.7000110.8M640 M643M640-F645 HydrophobicContact CB-CE2 4.34Å; M640-F645 HydrophobicContact CE-CD2 3.66Å; M640-F645 HydrophobicContact CE-CE2 3.35Å; M640-F645 HydrophobicContact CE-CG 4.38Å; M640-F645 HydrophobicContact CE-CZ 3.84Å; M640-F645 HydrophobicContact CG-CE2 3.84Å; M640-F645 HydrophobicContact CG-CZ 4.35Å; M640-F645 HydrophobicContact SD-CE2 4.07Å; M640-F645 HydrophobicContact SD-CZ 4.28Å; M643-F645 HydrophobicContact CB-CD2 3.91Å; M643-F645 HydrophobicContact CB-CE2 3.4Å; M643-F645 HydrophobicContact CB-CZ 4.2Å; M643-F645 HydrophobicContact CE-CE2 4.24Å; M643-F645 HydrophobicContact CE-CZ 3.84Å; M643-F645 HydrophobicContact CG-CE2 4.3Å; M643-F645 WeakPolarHBondContact O-CD2 3.42Å; M643-F645 PolarHBondContact O-N 2.91Å; M643-F645 VanDerWaalsContact O-N 3.13Å; M643-F645 HydrophobicContact SD-CE2 4.02Å; M643-F645 HydrophobicContact SD-CZ 4.06Å
646H66.8Low74.8Confident165 Ų165113 Ų11376%0.76458%0.578SS**PPolyproline II helixtrans-82.9129.9170-66.7-75.6000109.5K648H646-K648 PolarHBondContact O-N 3.12Å
647P70.1Confident74.4Confident130 Ų130119.2 Ų119.284%0.84462%0.616SS**PPolyproline II helixtrans-52.7131.6176.5-24.432000111.1
648K77.3Confident74.4Confident195 Ų195118.2 Ų118.285%0.84862%0.618SS**PPolyproline II helixtrans-79.9134.4174.2-69-172.1178.4-178.80109.2H646 Q650H646-K648 PolarHBondContact O-N 3.12Å; K648-Q650 PolarHBondContact O-N 2.95Å
649A80.4Confident74.5Confident35 Ų35118.1 Ų118.129%0.28963%0.627SS.*PPolyproline II helixtrans-62.5130.6171.100000110.2Q656A649-Q656 HydrophobicContact CB-CB 4.01Å
650Q81.9Confident74.7Confident108 Ų108123.6 Ų123.651%0.50566%0.661SS.*PPolyproline II helixtrans-81.6117.2175.6-68.3-176.3-13.700109.6K648 S652 I653K648-Q650 PolarHBondContact O-N 2.95Å; Q650-S652 PolarHBondContact O-N 3.48Å; Q650-S652 VanDerWaalsContact O-N 3.13Å; Q650-I653 HydrophobicContact CB-CB 4.46Å; Q650-I653 HydrophobicContact CB-CD1 4.41Å; Q650-I653 HydrophobicContact CB-CG1 4.18Å; Q650-I653 PolarHBondContact O-N 2.76Å; Q650-I653 VanDerWaalsContact O-N 3.07Å
651K72.4Confident74.8Confident220 Ų220128.6 Ų128.696%0.95769%0.685SS**THydrogen-bonded Turntrans-60.7-24.7-176.9-68.9-174.1177-176.90113.6
652S74.2Confident75.1Confident110 Ų110125.8 Ų125.877%0.76969%0.686SS**THydrogen-bonded Turntrans-79.5-16178.849.30000114.1Q650Q650-S652 PolarHBondContact O-N 3.48Å; Q650-S652 VanDerWaalsContact O-N 3.13Å
653I78.9Confident76Confident78 Ų78121.3 Ų121.340%0.469%0.687SS.*SBendtrans-101.8109.9-177.5-58.4-170.3000110.3Q650 G655 Q656Q650-I653 HydrophobicContact CB-CB 4.46Å; Q650-I653 HydrophobicContact CB-CD1 4.41Å; Q650-I653 HydrophobicContact CB-CG1 4.18Å; Q650-I653 PolarHBondContact O-N 2.76Å; Q650-I653 VanDerWaalsContact O-N 3.07Å; I653-G655 PolarHBondContact O-N 3.02Å; I653-Q656 HydrophobicContact CB-CG 4.39Å; I653-Q656 HydrophobicContact CG2-CG 4.19Å; I653-Q656 PolarHBondContact O-N 2.77Å
654K78.1Confident77Confident216 Ų216127.3 Ų127.394%0.93971%0.711SS**THydrogen-bonded Turntrans-63.1124.2174.6-145175.1-174.9179.80109.5
655G80.7Confident78.2Confident77 Ų77123 Ų12379%0.79470%0.702SS**THydrogen-bonded Turntrans110.9-8.4-178.400000115.3I653I653-G655 PolarHBondContact O-N 3.02Å
656Q85.5Confident79.6Confident90 Ų90126.3 Ų126.342%0.42172%0.723SS.*  trans-94.6123.1170-62.3-170.711.700110.9A649 I653A649-Q656 HydrophobicContact CB-CB 4.01Å; I653-Q656 HydrophobicContact CB-CG 4.39Å; I653-Q656 HydrophobicContact CG2-CG 4.19Å; I653-Q656 PolarHBondContact O-N 2.77Å
657V82.8Confident80.5Confident143 Ų143124.9 Ų124.987%0.86772%0.717SS**  trans-107.9114.2178.1-175.50000109.3
658G85.5Confident81.5Confident42 Ų42124.2 Ų124.243%0.43371%0.71SS.*  trans-90.8156.9176.700000112.5
659A85Confident82.1Confident90 Ų90123.2 Ų123.274%0.74471%0.705SS**  trans-66.8127.3171.900000110.2M661A659-M661 VanDerWaalsContact C-N 3.3Å; A659-M661 PolarHBondContact O-N 3.34Å
660P81.7Confident82.6Confident135 Ų135125.9 Ų125.988%0.87772%0.718SS**SBendtrans-75.7-20.1-178.329.3-34.3000113
661M75.8Confident83Confident142 Ų142128.9 Ų128.970%0.773%0.729SS**SBendtrans-153.7160.5179.259.6-177.1-80.200111.2A659A659-M661 VanDerWaalsContact C-N 3.3Å; A659-M661 PolarHBondContact O-N 3.34Å
662P78.1Confident83.6Confident124 Ų124125.8 Ų125.881%0.80573%0.729SS**  trans-60.3141175.3-22.233.9000112.5
663G83.4Confident84.3Confident81 Ų81124.4 Ų124.484%0.83573%0.732SS**  trans-178.8-176-18000000113.2
664K81Confident84.7Confident188 Ų188123.1 Ų123.182%0.81773%0.73SS**  trans-114.3137.5176.4-168.8177-179.9-177.90109.8L666K664-L666 PolarHBondContact O-N 3.4Å
665V84.1Confident85.2Confident112 Ų112122.9 Ų122.968%0.67973%0.729SS**  trans-70115.4171.9-178.90000108.1V668V665-V668 HydrophobicContact CG1-CG2 3.88Å
666L87.3Confident85.5Confident171 Ų171124.7 Ų124.790%0.89572%0.724SS**  trans-83.9-39.7178.1-65.8175.4000111.6K664K664-L666 PolarHBondContact O-N 3.4Å
667E87.4Confident85.4Confident136 Ų136125.9 Ų125.964%0.63674%0.742SS**  trans-154.4144-174.8-169.5-176.3-167.700110.1K669E667-K669 HydrophobicContact CG-CG 4.35Å; E667-K669 WeakPolarHBondContact OE2-CE 3.33Å
668V90.4Very high85Confident115 Ų115128.2 Ų128.270%0.69777%0.765SS**  trans-108.8105.9174.4-179.30000108.5V665 V670V665-V668 HydrophobicContact CG1-CG2 3.88Å; V668-V670 WeakPolarHBondContact CG1-O 3.1Å
669K90.1Very high84.9Confident174 Ų174132.6 Ų132.676%0.75778%0.782SS**  trans-85.9-9.6-170.9-64.7-169.6174.9-173.40115.4E667E667-K669 HydrophobicContact CG-CG 4.35Å; E667-K669 WeakPolarHBondContact OE2-CE 3.33Å
670V90.1Very high84.9Confident91 Ų91134.8 Ų134.855%0.55278%0.784SS**  trans-140.5154.5-175.7-660000110.8V668 V676V668-V670 WeakPolarHBondContact CG1-O 3.1Å; V670-V676 HydrophobicContact CG1-CG1 4.02Å
671K89.8Confident85.1Confident171 Ų171134.8 Ų134.874%0.74378%0.779SS**  trans-119.4161.6176.263.1-177.7179.2-177.20111.4G673 S674K671-G673 PolarHBondContact O-N 2.81Å; K671-S674 WeakPolarHBondContact CG-OG 3.38Å; K671-S674 PolarHBondContact N-OG 3.27Å; K671-S674 VanDerWaalsContact O-CB 3.29Å; K671-S674 WeakPolarHBondContact O-CB 3.46Å; K671-S674 PolarHBondContact O-N 3.31Å; K671-S674 PolarHBondContact O-OG 3.21Å
672V86.4Confident85.7Confident156 Ų156134.4 Ų134.495%0.94578%0.783SS**THydrogen-bonded Turntrans-52.6130.5176.2-179.20000110
673G87.6Confident86.1Confident81 Ų81135 Ų13584%0.83578%0.782SS**THydrogen-bonded Turntrans89.2-2.5-177.600000115.8K671K671-G673 PolarHBondContact O-N 2.81Å
674S88.6Confident86.3Confident51 Ų51138.6 Ų138.636%0.35778%0.778SS.*  trans-71.6132.2176.1-51.70000110.9K671K671-S674 WeakPolarHBondContact CG-OG 3.38Å; K671-S674 PolarHBondContact N-OG 3.27Å; K671-S674 VanDerWaalsContact O-CB 3.29Å; K671-S674 WeakPolarHBondContact O-CB 3.46Å; K671-S674 PolarHBondContact O-N 3.31Å; K671-S674 PolarHBondContact O-OG 3.21Å
675K87.9Confident86.7Confident211 Ų211135.1 Ų135.192%0.91778%0.776SS**  trans-76.4131.1167.5-72-175.6177.8-179.30109.2
676V86.9Confident86.9Confident114 Ų114136.8 Ų136.869%0.69178%0.783SS**  trans-125143.6177.4-66.40000109.1V670V670-V676 HydrophobicContact CG1-CG1 4.02Å
677S83.6Confident86.9Confident116 Ų116134 Ų13481%0.81177%0.774SS**  trans-102.6147.5173.754.30000110.4
678S73.7Confident86.8Confident192 Ų192133.8 Ų133.8100%1.34379%0.786SS**  trans-66.10177.458.50000112.8

Retrieved 678 of 678 residues in 632.4 ms (Link to these results)