A0A087XS54_POEFO Loading...

Solute carrier family 38 member 6

AlphaFold DB , UniProt , Accession A0A087XS54, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 457 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32.6	Very low	29.7	Very low	242 Å²	242	127.6 Å²	127.6	100%	1.192	72%	0.72	S	S	*	*				0	104.3	0	-145	165.6	-174.1	0	0	106.4
2	S	29.4	Very low	29.7	Very low	120 Å²	120	133.4 Å²	133.4	84%	0.839	72%	0.724	S	S	*	*	P	Polyproline II helix	trans	-76.7	117.6	-170.5	47.9	0	0	0	0	110.8
3	I	27.7	Very low	29.7	Very low	156 Å²	156	131.3 Å²	131.3	80%	0.8	72%	0.718	S	S	*	*	P	Polyproline II helix	trans	-97.6	124.5	173.1	-61.4	176.8	0	0	0	107.6
4	N	25.8	Very low	29.5	Very low	121 Å²	121	137.6 Å²	137.6	65%	0.647	73%	0.726	S	S	*	*	P	Polyproline II helix	trans	-64.2	132.7	-172.1	-103.8	-15.4	0	0	0	112.3	S6	N4-S6 PolarHBondContact O-N 3.12Å; N4-S6 VanDerWaalsContact O-N 3.11Å
5	S	31.3	Very low	29.5	Very low	111 Å²	111	138.3 Å²	138.3	78%	0.776	73%	0.729	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.5	4.9	175.3	48	0	0	0	0	114.5
6	S	31.5	Very low	29.5	Very low	70 Å²	70	136.8 Å²	136.8	49%	0.49	73%	0.734	S	S	.	*	T	Hydrogen-bonded Turn	trans	-89.2	-23	-178.8	58.2	0	0	0	0	114.1	N4	N4-S6 PolarHBondContact O-N 3.12Å; N4-S6 VanDerWaalsContact O-N 3.11Å
7	E	30.6	Very low	29.5	Very low	143 Å²	143	132.3 Å²	132.3	67%	0.668	73%	0.727	S	S	*	*	H	α-helix	trans	-81.8	-21.6	-177.3	-90.6	-176.5	141.4	0	0	114.2	A9	E7-A9 VanDerWaalsContact C-N 3.31Å; E7-A9 PolarHBondContact O-N 2.93Å
8	Q	30.3	Very low	29.3	Very low	163 Å²	163	137.8 Å²	137.8	76%	0.762	74%	0.735	S	S	*	*	H	α-helix	trans	-75.2	-19.6	176.6	-90.2	177.2	-26.7	0	0	113.5
9	A	30.9	Very low	29.5	Very low	65 Å²	65	139.4 Å²	139.4	54%	0.537	74%	0.744	S	S	.	*	H	α-helix	trans	-76	-31.5	177	0	0	0	0	0	112.5	E7	E7-A9 VanDerWaalsContact C-N 3.31Å; E7-A9 PolarHBondContact O-N 2.93Å
10	D	28	Very low	29.5	Very low	119 Å²	119	137.2 Å²	137.2	64%	0.636	74%	0.74	S	S	*	*	H	α-helix	trans	-80.3	-19.3	-174.9	-86.2	-20.4	0	0	0	114.1
11	V	28.5	Very low	29.5	Very low	94 Å²	94	138 Å²	138	57%	0.57	75%	0.749	S	S	*	*	H	α-helix	trans	-78.5	-31.1	179.9	179.6	0	0	0	0	111.8	T13 R14	V11-T13 VanDerWaalsContact C-N 3.33Å; V11-T13 PolarHBondContact O-N 3.11Å; V11-R14 PolarHBondContact O-N 2.91Å
12	Y	29.9	Very low	29.3	Very low	197 Å²	197	132.1 Å²	132.1	77%	0.773	73%	0.727	S	S	*	*	H	α-helix	trans	-72.1	-23.7	-179.7	-96.2	-83.7	0	0	0	113.7
13	T	29.7	Very low	29.2	Very low	106 Å²	106	131.1 Å²	131.1	65%	0.65	72%	0.72	S	S	*	*	H	α-helix	trans	-76.9	-23.8	179.6	-44.3	0	0	0	0	112.8	V11 L15	V11-T13 VanDerWaalsContact C-N 3.33Å; V11-T13 PolarHBondContact O-N 3.11Å; T13-L15 PolarHBondContact O-N 3.38Å
14	R	26.8	Very low	29.5	Very low	220 Å²	220	132.1 Å²	132.1	83%	0.83	72%	0.721	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.2	-15	-178.2	-71.6	-168.8	-170.9	174.4	4.6	114.9	V11	V11-R14 PolarHBondContact O-N 2.91Å
15	L	29.9	Very low	30.1	Very low	147 Å²	147	133.6 Å²	133.6	77%	0.77	73%	0.729	S	S	*	*	S	Bend	trans	-97.5	-11.6	-176	-79.9	152.6	0	0	0	114.3	T13	T13-L15 PolarHBondContact O-N 3.38Å
16	S	28.9	Very low	30.4	Very low	115 Å²	115	134.6 Å²	134.6	80%	0.804	73%	0.73	S	S	*	*	S	Bend	trans	-93	2.1	178	-171.1	0	0	0	0	114.4
17	G	29.1	Very low	30.5	Very low	60 Å²	60	137.2 Å²	137.2	62%	0.619	75%	0.746	S	S	*	*			trans	-113.3	14.7	-170.8	0	0	0	0	0	116
18	R	27.1	Very low	30.9	Very low	232 Å²	232	138.5 Å²	138.5	88%	0.875	76%	0.756	S	S	*	*			trans	-107.8	66.9	-174.2	-153	170.6	-173.2	161.6	0.4	111.6
19	D	32.9	Very low	31.5	Very low	167 Å²	167	139.5 Å²	139.5	89%	0.893	77%	0.766	S	S	*	*			trans	-164.4	79.7	155.1	-89.7	-26.5	0	0	0	109.3
20	S	28.5	Very low	31.5	Very low	95 Å²	95	140 Å²	140	66%	0.664	78%	0.777	S	S	*	*			trans	-154.2	115.7	151	49.9	0	0	0	0	108.7	V22	S20-V22 PolarHBondContact O-N 2.86Å; S20-V22 VanDerWaalsContact O-N 3.11Å
21	V	29.8	Very low	31.7	Very low	154 Å²	154	142.2 Å²	142.2	93%	0.933	79%	0.789	S	S	*	*			trans	-65.6	104.7	164.9	174.4	0	0	0	0	106.1
22	V	29.2	Very low	32.2	Very low	119 Å²	119	141.1 Å²	141.1	72%	0.721	80%	0.797	S	S	*	*			trans	-85.2	110.7	173.4	176.2	0	0	0	0	107.6	S20	S20-V22 PolarHBondContact O-N 2.86Å; S20-V22 VanDerWaalsContact O-N 3.11Å
23	S	26.7	Very low	32.1	Very low	99 Å²	99	136.9 Å²	136.9	69%	0.692	80%	0.796	S	S	*	*			trans	-62.5	124.4	160.6	177.1	0	0	0	0	108.4	N25	S23-N25 PolarHBondContact O-N 2.85Å; S23-N25 VanDerWaalsContact O-N 3.12Å
24	E	34.2	Very low	32.5	Very low	178 Å²	178	138.1 Å²	138.1	83%	0.832	80%	0.803	S	S	*	*	S	Bend	trans	-58.2	112.7	165.3	-75.7	177.1	143.4	0	0	108.8
25	N	37.7	Very low	32.9	Very low	151 Å²	151	136.4 Å²	136.4	81%	0.807	81%	0.805	S	S	*	*			trans	163.5	84.4	150.4	-82.6	-18.7	0	0	0	109.5	S23	S23-N25 PolarHBondContact O-N 2.85Å; S23-N25 VanDerWaalsContact O-N 3.12Å
26	T	37.8	Very low	33.1	Very low	132 Å²	132	135.5 Å²	135.5	81%	0.81	81%	0.805	S	S	*	*			trans	-158	139.9	160.3	-5	0	0	0	0	109.2
27	P	34.2	Very low	33.7	Very low	125 Å²	125	140.8 Å²	140.8	81%	0.812	81%	0.808	S	S	*	*			trans	-77.5	147	-160.8	31.9	-32	0	0	0	112.4
28	L	39.8	Very low	35	Very low	170 Å²	170	142.7 Å²	142.7	89%	0.89	82%	0.818	S	S	*	*	S	Bend	trans	-70	135.2	171.7	-75.2	155.4	0	0	0	110.3
29	L	42.4	Very low	37.1	Very low	184 Å²	184	137.6 Å²	137.6	96%	0.963	81%	0.813	S	S	*	*			trans	95.4	93.4	174.1	-59.3	161.9	0	0	0	116.6
30	G	30	Very low	39.3	Very low	75 Å²	75	131.1 Å²	131.1	77%	0.773	79%	0.785	S	S	*	*			trans	-131.5	116.6	157.3	0	0	0	0	0	109.2
31	N	31.9	Very low	42	Very low	166 Å²	166	127.8 Å²	127.8	89%	0.888	76%	0.763	S	S	*	*			trans	-42.3	134.8	-176.4	-155.3	13.8	0	0	0	114	S33	N31-S33 PolarHBondContact O-N 3.46Å
32	G	39.3	Very low	45	Very low	72 Å²	72	123.2 Å²	123.2	74%	0.742	74%	0.738	S	S	*	*			trans	-63.6	96.7	-174.5	0	0	0	0	0	113.5	V34	G32-V34 PolarHBondContact O-N 3.42Å
33	S	29.2	Very low	48	Very low	108 Å²	108	120.4 Å²	120.4	76%	0.755	72%	0.719	S	S	*	*			trans	-74.7	109.2	149.9	58.8	0	0	0	0	106.9	N31 Q35	N31-S33 PolarHBondContact O-N 3.46Å; S33-Q35 PolarHBondContact O-N 3.48Å
34	V	37.3	Very low	51.1	Low	131 Å²	131	118.4 Å²	118.4	79%	0.794	71%	0.708	S	S	*	*			trans	-41.4	111	162.8	173.8	0	0	0	0	107.2	G32 T36	G32-V34 PolarHBondContact O-N 3.42Å; V34-T36 PolarHBondContact O-N 3.08Å
35	Q	34.3	Very low	53.8	Low	185 Å²	185	111.1 Å²	111.1	86%	0.864	68%	0.677	S	S	*	*			trans	-62.3	104.1	175.7	-165.5	162.5	9.1	0	0	105.8	S33 R37	S33-Q35 PolarHBondContact O-N 3.48Å; Q35-R37 PolarHBondContact O-N 2.83Å
36	T	35.5	Very low	56.4	Low	127 Å²	127	103.9 Å²	103.9	78%	0.779	64%	0.638	S	S	*	*			trans	-51.9	107	179.9	-39.2	0	0	0	0	106.6	V34 A38	V34-T36 PolarHBondContact O-N 3.08Å; T36-A38 PolarHBondContact O-N 3.48Å; T36-A38 VanDerWaalsContact O-N 3.08Å
37	R	41.3	Very low	59.1	Low	226 Å²	226	98.1 Å²	98.1	85%	0.853	60%	0.602	S	S	*	*			trans	-47.1	123.4	171	-88.6	177.9	169.8	162.2	-3	106	Q35 T39	Q35-R37 PolarHBondContact O-N 2.83Å; R37-T39 PolarHBondContact O-N 3.11Å
38	A	55.6	Low	61.9	Low	101 Å²	101	94.9 Å²	94.9	84%	0.835	58%	0.576	S	S	*	*			trans	-52	109	171.3	0	0	0	0	0	107	T36 G40	T36-A38 PolarHBondContact O-N 3.48Å; T36-A38 VanDerWaalsContact O-N 3.08Å; A38-G40 PolarHBondContact O-N 2.9Å; A38-G40 VanDerWaalsContact O-N 3.16Å
39	T	71.1	Confident	64.3	Low	124 Å²	124	87.5 Å²	87.5	76%	0.761	54%	0.537	S	S	*	.	P	Polyproline II helix	trans	-64.2	116.4	177.7	40.9	0	0	0	0	106.5	R37	R37-T39 PolarHBondContact O-N 3.11Å
40	G	79.4	Confident	66.7	Low	31 Å²	31	78.8 Å²	78.8	32%	0.32	49%	0.492	S	S	.	.	P	Polyproline II helix	trans	-56.9	164.9	177.7	0	0	0	0	0	112	A38 E272	A38-G40 PolarHBondContact O-N 2.9Å; A38-G40 VanDerWaalsContact O-N 3.16Å; G40-E272 CarbonylContact C-O 3.41Å; G40-E272 WeakPolarHBondContact CA-O 3.48Å
41	A	86.1	Confident	69.7	Low	25 Å²	25	75.2 Å²	75.2	21%	0.207	46%	0.455	C	S	.	.	B	Isolated β-bridge	trans	-64.7	139	179	0	0	0	0	0	111.3	E272 E274	A41-E272 HydrophobicContact CB-CB 4.48Å; A41-E272 PolarHBondContact N-O 3.33Å; A41-E274 WeakPolarHBondContact O-CB 3.25Å; A41-E274 PolarHBondContact O-N 3.06Å
42	S	91.5	Very high	72.5	Confident	58 Å²	58	67.9 Å²	67.9	41%	0.406	42%	0.416	S	S	.	.	P	Polyproline II helix	trans	-66.9	156.7	176.2	72	0	0	0	0	111.3	A44 S45 C46	S42-A44 PolarHBondContact O-N 3.12Å; S42-S45 WeakPolarHBondContact O-CB 3.46Å; S42-S45 PolarHBondContact O-N 3.07Å; S42-S45 PolarHBondContact OG-N 3.48Å; S42-C46 PolarHBondContact O-N 3.44Å; S42-C46 PolarHBondContact O-SG 3.34Å
43	I	92.9	Very high	75	Confident	61 Å²	61	66 Å²	66	31%	0.313	39%	0.393	S	S	.	.	H	α-helix	trans	-52.7	-42.4	176.2	-68.1	174.4	0	0	0	111.1	C46 V47 L273 V284	I43-C46 PolarHBondContact O-N 2.97Å; I43-V47 HydrophobicContact CG2-CG2 4.39Å; I43-V47 VanDerWaalsContact O-CG2 3.3Å; I43-V47 WeakPolarHBondContact O-CG2 3.23Å; I43-V47 PolarHBondContact O-N 2.81Å; I43-L273 HydrophobicContact CG1-CD1 4.11Å; I43-V284 HydrophobicContact CG2-CG2 3.9Å
44	A	92.1	Very high	78	Confident	56 Å²	56	61 Å²	61	46%	0.463	36%	0.358	S	S	.	.	H	α-helix	trans	-63.3	-43	178.7	0	0	0	0	0	112.2	S42 C46 V47 F48	S42-A44 PolarHBondContact O-N 3.12Å; A44-C46 PolarHBondContact O-N 3.35Å; A44-V47 WeakPolarHBondContact O-CB 3.47Å; A44-V47 PolarHBondContact O-N 3.16Å; A44-F48 WeakPolarHBondContact O-CD2 3.42Å; A44-F48 PolarHBondContact O-N 3.17Å
45	S	90	Very high	80.4	Confident	25 Å²	25	54.9 Å²	54.9	18%	0.175	32%	0.32	C	S	.	.	H	α-helix	trans	-63.3	-42	175.9	-170.9	0	0	0	0	111.6	S42 V47 F48 N49	S42-S45 WeakPolarHBondContact O-CB 3.46Å; S42-S45 PolarHBondContact O-N 3.07Å; S42-S45 PolarHBondContact OG-N 3.48Å; S45-V47 VanDerWaalsContact C-N 3.33Å; S45-F48 PolarHBondContact O-N 3.41Å; S45-N49 WeakPolarHBondContact O-CB 3.46Å; S45-N49 VanDerWaalsContact O-CG 3.26Å; S45-N49 PolarHBondContact O-N 3.25Å
46	C	92.3	Very high	82.7	Confident	0 Å²	0	46.7 Å²	46.7	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-63.9	-38.5	175.4	-64.9	0	0	0	0	111.8	S42 I43 A44 N49 L50 I269 L273 V284	S42-C46 PolarHBondContact O-N 3.44Å; S42-C46 PolarHBondContact O-SG 3.34Å; I43-C46 PolarHBondContact O-N 2.97Å; A44-C46 PolarHBondContact O-N 3.35Å; C46-N49 PolarHBondContact O-N 3.09Å; C46-L50 WeakPolarHBondContact O-CB 3.32Å; C46-L50 PolarHBondContact O-N 2.9Å; C46-I269 HydrophobicContact CB-CG2 3.64Å; C46-L273 HydrophobicContact CB-CD1 4.25Å; C46-L273 VanDerWaalsContact SG-CD1 3.57Å; C46-V284 HydrophobicContact CB-CG1 3.87Å; C46-V284 HydrophobicContact CB-CG2 4.07Å
47	V	95	Very high	85.2	Confident	10 Å²	10	40.8 Å²	40.8	6%	0.061	25%	0.249	C	C	.	.	H	α-helix	trans	-61	-49.3	175.5	164.6	0	0	0	0	110.7	I43 A44 S45 L50 M51 V284 I287 S288	I43-V47 HydrophobicContact CG2-CG2 4.39Å; I43-V47 VanDerWaalsContact O-CG2 3.3Å; I43-V47 WeakPolarHBondContact O-CG2 3.23Å; I43-V47 PolarHBondContact O-N 2.81Å; A44-V47 WeakPolarHBondContact O-CB 3.47Å; A44-V47 PolarHBondContact O-N 3.16Å; S45-V47 VanDerWaalsContact C-N 3.33Å; V47-L50 PolarHBondContact O-N 3.16Å; V47-M51 HydrophobicContact CG1-CG 4.39Å; V47-M51 HydrophobicContact CG1-SD 3.55Å; V47-M51 VanDerWaalsContact CG1-SD 3.55Å; V47-M51 WeakPolarHBondContact O-CB 3.08Å; V47-M51 WeakPolarHBondContact O-CG 3.35Å; V47-M51 PolarHBondContact O-N 3.27Å; V47-V284 HydrophobicContact CG2-CB 4.3Å; V47-V284 HydrophobicContact CG2-CG1 3.96Å; V47-V284 HydrophobicContact CG2-CG2 4.35Å; V47-I287 HydrophobicContact CG1-CG2 3.9Å; V47-I287 HydrophobicContact CG2-CB 4.19Å; V47-I287 HydrophobicContact CG2-CG2 4.09Å; V47-S288 VanDerWaalsContact CA-OG 3.29Å; V47-S288 WeakPolarHBondContact CA-OG 3.34Å; V47-S288 PolarHBondContact O-OG 3.36Å
48	F	91.9	Very high	87.4	Confident	58 Å²	58	30 Å²	30	25%	0.254	21%	0.209	S	C	.	.	H	α-helix	trans	-66.4	-38.6	178.6	-65.8	-49.2	0	0	0	112.7	A44 S45 M51 N52 S193 F196	A44-F48 WeakPolarHBondContact O-CD2 3.42Å; A44-F48 PolarHBondContact O-N 3.17Å; S45-F48 PolarHBondContact O-N 3.41Å; F48-M51 HydrophobicContact CD1-SD 4.39Å; F48-M51 PolarHBondContact O-N 3.33Å; F48-N52 WeakPolarHBondContact O-CB 3.39Å; F48-N52 PolarHBondContact O-N 2.68Å; F48-S193 WeakPolarHBondContact CD2-OG 3.35Å; F48-F196 HydrophobicContact CD1-CB 4.17Å; F48-F196 HydrophobicContact CD1-CD1 4.08Å; F48-F196 HydrophobicContact CD1-CG 4.07Å; F48-F196 AromaticContact CE1-CD1 3.67Å; F48-F196 HydrophobicContact CE1-CD1 3.67Å; F48-F196 HydrophobicContact CE1-CE1 4.01Å; F48-F196 HydrophobicContact CE1-CG 4.1Å
49	N	90.8	Very high	89.2	Confident	15 Å²	15	25.3 Å²	25.3	8%	0.08	17%	0.17	C	C	.	.	H	α-helix	trans	-61.8	-45.4	174.3	-75.2	-10.5	0	0	0	111.5	S45 C46 N52 A53 S192 I269	S45-N49 WeakPolarHBondContact O-CB 3.46Å; S45-N49 VanDerWaalsContact O-CG 3.26Å; S45-N49 PolarHBondContact O-N 3.25Å; C46-N49 PolarHBondContact O-N 3.09Å; N49-N52 PolarHBondContact O-N 2.91Å; N49-A53 PolarHBondContact O-N 3.41Å; N49-S192 WeakPolarHBondContact OD1-CB 3.33Å; N49-S192 PolarHBondContact OD1-OG 3.34Å; N49-I269 HydrophobicContact CB-CD1 3.93Å; N49-I269 HydrophobicContact CB-CG1 4.32Å
50	L	93.4	Very high	90.2	Very high	0 Å²	0	19.5 Å²	19.5	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-68.9	-37.2	179.3	-170.7	65.3	0	0	0	111.5	C46 V47 A53 I54 C262 I266 I269 V284 A285	C46-L50 WeakPolarHBondContact O-CB 3.32Å; C46-L50 PolarHBondContact O-N 2.9Å; V47-L50 PolarHBondContact O-N 3.16Å; L50-A53 WeakPolarHBondContact O-CB 3.41Å; L50-A53 PolarHBondContact O-N 2.96Å; L50-I54 HydrophobicContact CG-CD1 4.47Å; L50-I54 WeakPolarHBondContact O-CG1 3.26Å; L50-I54 PolarHBondContact O-N 3.39Å; L50-I54 VanDerWaalsContact O-N 3.13Å; L50-C262 HydrophobicContact CD1-CB 3.64Å; L50-C262 HydrophobicContact CG-CB 4.42Å; L50-I266 HydrophobicContact CD1-CB 4.3Å; L50-I266 HydrophobicContact CD1-CG1 4.38Å; L50-I269 HydrophobicContact CB-CD1 3.99Å; L50-I269 HydrophobicContact CD1-CD1 4.03Å; L50-V284 HydrophobicContact CD2-CG1 4.13Å; L50-A285 HydrophobicContact CD2-CB 4.19Å
51	M	93.2	Very high	90.8	Very high	1 Å²	1	18.1 Å²	18.1	1%	0.005	12%	0.12	C	C	.	.	H	α-helix	trans	-65.6	-38.1	173.6	-73	169.6	68.3	0	0	112.5	V47 F48 A53 I54 M55 F196 L291	V47-M51 HydrophobicContact CG1-CG 4.39Å; V47-M51 HydrophobicContact CG1-SD 3.55Å; V47-M51 VanDerWaalsContact CG1-SD 3.55Å; V47-M51 WeakPolarHBondContact O-CB 3.08Å; V47-M51 WeakPolarHBondContact O-CG 3.35Å; V47-M51 PolarHBondContact O-N 3.27Å; F48-M51 HydrophobicContact CD1-SD 4.39Å; F48-M51 PolarHBondContact O-N 3.33Å; M51-A53 PolarHBondContact O-N 3.46Å; M51-I54 PolarHBondContact O-N 3.38Å; M51-I54 VanDerWaalsContact O-N 3.09Å; M51-M55 HydrophobicContact CB-CE 4.35Å; M51-M55 HydrophobicContact CE-CE 3.16Å; M51-M55 HydrophobicContact CE-SD 4.23Å; M51-M55 WeakPolarHBondContact O-CB 3.33Å; M51-M55 WeakPolarHBondContact O-CG 3.33Å; M51-M55 PolarHBondContact O-N 2.9Å; M51-F196 HydrophobicContact CE-CD2 3.27Å; M51-F196 HydrophobicContact CE-CE2 3.24Å; M51-F196 HydrophobicContact CE-CG 4.28Å; M51-F196 HydrophobicContact CE-CZ 4.23Å; M51-L291 HydrophobicContact CE-CB 3.87Å; M51-L291 HydrophobicContact CE-CD2 3.31Å; M51-L291 HydrophobicContact CE-CG 3.41Å; M51-L291 VanDerWaalsContact CE-CG 3.41Å; M51-L291 HydrophobicContact SD-CB 4.24Å; M51-L291 HydrophobicContact SD-CD2 3.73Å; M51-L291 HydrophobicContact SD-CG 4.22Å
52	N	90.9	Very high	91.2	Very high	12 Å²	12	17 Å²	17	6%	0.064	11%	0.11	C	C	.	.	H	α-helix	trans	-62.7	-34.5	175	-167.1	35	0	0	0	111.5	F48 N49 A195 T343 L346	F48-N52 WeakPolarHBondContact O-CB 3.39Å; F48-N52 PolarHBondContact O-N 2.68Å; N49-N52 PolarHBondContact O-N 2.91Å; N52-A195 VanDerWaalsContact OD1-CB 3.31Å; N52-A195 WeakPolarHBondContact OD1-CB 3.4Å; N52-T343 PolarHBondContact OD1-OG1 3.14Å; N52-L346 WeakPolarHBondContact ND2-CD1 3.47Å
53	A	90.3	Very high	91.5	Very high	31 Å²	31	14.2 Å²	14.2	26%	0.256	9%	0.091	S	C	.	.	H	α-helix	trans	-68.6	-31.2	172.9	0	0	0	0	0	113.3	N49 L50 M51 C262 A265	N49-A53 PolarHBondContact O-N 3.41Å; L50-A53 WeakPolarHBondContact O-CB 3.41Å; L50-A53 PolarHBondContact O-N 2.96Å; M51-A53 PolarHBondContact O-N 3.46Å; A53-C262 HydrophobicContact CB-CB 4.4Å; A53-A265 HydrophobicContact CB-CB 3.77Å
54	I	93.6	Very high	91.5	Very high	4 Å²	4	12 Å²	12	2%	0.021	8%	0.079	C	C	.	.	H	α-helix	trans	-79.2	-63.1	177	-63	164.7	0	0	0	110	L50 M51 G56 S259 F260 C262 I289 Y296	L50-I54 HydrophobicContact CG-CD1 4.47Å; L50-I54 WeakPolarHBondContact O-CG1 3.26Å; L50-I54 PolarHBondContact O-N 3.39Å; L50-I54 VanDerWaalsContact O-N 3.13Å; M51-I54 PolarHBondContact O-N 3.38Å; M51-I54 VanDerWaalsContact O-N 3.09Å; I54-G56 PolarHBondContact O-N 3.28Å; I54-S259 CarbonylContact C-O 3.59Å; I54-S259 WeakPolarHBondContact CG2-O 3.11Å; I54-F260 HydrophobicContact CG2-CD1 4.01Å; I54-F260 HydrophobicContact CG2-CE1 4.44Å; I54-C262 HydrophobicContact CD1-CB 4.34Å; I54-C262 HydrophobicContact CG1-CB 3.67Å; I54-I289 HydrophobicContact CD1-CG1 3.78Å; I54-Y296 VanDerWaalsContact C-OH 3.28Å; I54-Y296 HydrophobicContact CG2-CE2 3.92Å; I54-Y296 PolarHBondContact O-OH 2.85Å
55	M	88.3	Confident	91.6	Very high	2 Å²	2	9.4 Å²	9.4	1%	0.01	6%	0.057	C	C	.	.	H	α-helix	trans	-56.4	-51	-160.9	-74.2	-176.1	179	0	0	114.3	M51 I59 F196 M199 L295 Y296	M51-M55 HydrophobicContact CB-CE 4.35Å; M51-M55 HydrophobicContact CE-CE 3.16Å; M51-M55 HydrophobicContact CE-SD 4.23Å; M51-M55 WeakPolarHBondContact O-CB 3.33Å; M51-M55 WeakPolarHBondContact O-CG 3.33Å; M51-M55 PolarHBondContact O-N 2.9Å; M55-I59 PolarHBondContact O-N 3.21Å; M55-F196 HydrophobicContact CE-CD2 4.08Å; M55-F196 HydrophobicContact CE-CE2 4.19Å; M55-F196 HydrophobicContact SD-CD2 4.09Å; M55-M199 HydrophobicContact CB-CE 4.13Å; M55-M199 HydrophobicContact CB-CG 4.21Å; M55-M199 HydrophobicContact SD-CB 3.91Å; M55-M199 HydrophobicContact SD-CG 4.15Å; M55-L295 HydrophobicContact CE-CB 4.33Å; M55-L295 HydrophobicContact CE-CD1 3.2Å; M55-L295 HydrophobicContact CE-CG 4.31Å; M55-L295 HydrophobicContact SD-CD1 4.06Å; M55-Y296 WeakPolarHBondContact CA-OH 3.47Å; M55-Y296 HydrophobicContact CB-CE1 4.44Å; M55-Y296 HydrophobicContact CG-CE1 4.34Å; M55-Y296 PolarHBondContact O-OH 3.49Å
56	G	82.1	Confident	91.9	Very high	13 Å²	13	8.2 Å²	8.2	13%	0.134	5%	0.049	C	C	.	.	T	Hydrogen-bonded Turn	trans	28.5	-146.1	170.1	0	0	0	0	0	119.2	I54 G58 Y135	I54-G56 PolarHBondContact O-N 3.28Å; G56-G58 PolarHBondContact O-N 2.77Å; G56-Y135 WeakPolarHBondContact CA-OH 3.02Å
57	S	87.3	Confident	92	Very high	3 Å²	3	9 Å²	9	2%	0.021	6%	0.055	C	C	.	.	T	Hydrogen-bonded Turn	trans	-75.1	-17.7	177.2	57.4	0	0	0	0	112.1	I59 L60 S134 I138 F395	S57-I59 VanDerWaalsContact C-N 3.29Å; S57-I59 PolarHBondContact O-N 3.31Å; S57-L60 PolarHBondContact O-N 2.86Å; S57-S134 WeakPolarHBondContact OG-CB 3.4Å; S57-S134 PolarHBondContact OG-OG 2.88Å; S57-I138 VanDerWaalsContact CB-CD1 3.42Å; S57-F395 WeakPolarHBondContact O-CZ 3.41Å
58	G	87.6	Confident	91.8	Very high	1 Å²	1	8.9 Å²	8.9	1%	0.01	6%	0.055	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.6	-37.8	-175.2	0	0	0	0	0	113	G56 L60 G61 L62 S259	G56-G58 PolarHBondContact O-N 2.77Å; G58-L60 PolarHBondContact O-N 3.22Å; G58-G61 PolarHBondContact O-N 3.28Å; G58-L62 WeakPolarHBondContact O-CG 3.47Å; G58-L62 PolarHBondContact O-N 3.41Å; G58-S259 VanDerWaalsContact CA-OG 3.25Å; G58-S259 WeakPolarHBondContact CA-OG 3.23Å
59	I	93.3	Very high	91.9	Very high	2 Å²	2	6.4 Å²	6.4	1%	0.01	5%	0.045	C	C	.	.	H	α-helix	trans	-54.3	-34.1	-179	-156.2	166.1	0	0	0	113	M55 S57 G61 L62 M199 F202 Y296	M55-I59 PolarHBondContact O-N 3.21Å; S57-I59 VanDerWaalsContact C-N 3.29Å; S57-I59 PolarHBondContact O-N 3.31Å; I59-G61 VanDerWaalsContact C-N 3.29Å; I59-G61 PolarHBondContact O-N 3.41Å; I59-L62 PolarHBondContact O-N 3.43Å; I59-M199 HydrophobicContact CB-CE 3.9Å; I59-M199 HydrophobicContact CD1-CE 3.95Å; I59-M199 HydrophobicContact CG2-CE 3.25Å; I59-F202 HydrophobicContact CD1-CD1 3.99Å; I59-F202 HydrophobicContact CD1-CE1 3.86Å; I59-F202 HydrophobicContact CG1-CE1 3.95Å; I59-F202 HydrophobicContact CG2-CD1 4.45Å; I59-F202 HydrophobicContact CG2-CE1 3.97Å; I59-F202 HydrophobicContact CG2-CZ 4.47Å; I59-Y296 HydrophobicContact CB-CD1 4.14Å; I59-Y296 HydrophobicContact CB-CE1 3.77Å; I59-Y296 HydrophobicContact CD1-CD1 3.88Å; I59-Y296 HydrophobicContact CD1-CE1 4.1Å; I59-Y296 HydrophobicContact CG1-CD1 3.7Å; I59-Y296 HydrophobicContact CG1-CE1 3.86Å
60	L	92.3	Very high	92.1	Very high	2 Å²	2	5.7 Å²	5.7	1%	0.01	4%	0.041	C	C	.	.	H	α-helix	trans	-74	-23.5	-173.6	-61.6	179	0	0	0	112.4	S57 G58 I138 F202 E314 L315 L316 I336	S57-L60 PolarHBondContact O-N 2.86Å; G58-L60 PolarHBondContact O-N 3.22Å; L60-I138 HydrophobicContact CD1-CD1 3.55Å; L60-I138 HydrophobicContact CD1-CG1 3.86Å; L60-I138 HydrophobicContact CD1-CG2 4.33Å; L60-F202 HydrophobicContact CD2-CE1 4.39Å; L60-F202 HydrophobicContact CD2-CE2 3.7Å; L60-F202 HydrophobicContact CD2-CZ 3.58Å; L60-E314 HydrophobicContact CB-CG 4.2Å; L60-E314 HydrophobicContact CD1-CG 4.23Å; L60-L315 PolarHBondContact O-N 3.44Å; L60-L316 HydrophobicContact CD1-CD1 3.79Å; L60-L316 HydrophobicContact CD2-CD1 3.34Å; L60-L316 HydrophobicContact CD2-CG 4.26Å; L60-L316 HydrophobicContact CG-CD1 4.21Å; L60-I336 HydrophobicContact CD1-CG2 4.48Å; L60-I336 HydrophobicContact CD2-CD1 4.23Å
61	G	92.2	Very high	92.2	Very high	2 Å²	2	7.2 Å²	7.2	2%	0.021	5%	0.049	C	C	.	.	H	α-helix	trans	-91.8	-11	175.9	0	0	0	0	0	114.4	G58 I59 Y64 A65 S313	G58-G61 PolarHBondContact O-N 3.28Å; I59-G61 VanDerWaalsContact C-N 3.29Å; I59-G61 PolarHBondContact O-N 3.41Å; G61-Y64 WeakPolarHBondContact O-CB 3.41Å; G61-Y64 PolarHBondContact O-N 3.24Å; G61-A65 PolarHBondContact O-N 3.43Å; G61-A65 VanDerWaalsContact O-N 3.08Å; G61-S313 WeakPolarHBondContact CA-O 3.37Å
62	L	95.3	Very high	92.3	Very high	0 Å²	0	11 Å²	11	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-73.1	-32.1	-174	-69.5	177.2	0	0	0	113.5	G58 I59 Y64 A65 M66 F74 T255 M256 Y296 A300	G58-L62 WeakPolarHBondContact O-CG 3.47Å; G58-L62 PolarHBondContact O-N 3.41Å; I59-L62 PolarHBondContact O-N 3.43Å; L62-Y64 VanDerWaalsContact C-N 3.28Å; L62-Y64 PolarHBondContact O-N 3.17Å; L62-A65 WeakPolarHBondContact O-CB 3.44Å; L62-A65 PolarHBondContact O-N 3.36Å; L62-M66 PolarHBondContact O-N 3.2Å; L62-F74 HydrophobicContact CB-CE2 4.23Å; L62-F74 HydrophobicContact CB-CZ 4.17Å; L62-F74 HydrophobicContact CD2-CE2 4.29Å; L62-F74 HydrophobicContact CD2-CZ 4.48Å; L62-F74 VanDerWaalsContact O-CE2 3.28Å; L62-F74 WeakPolarHBondContact O-CE2 3.43Å; L62-T255 HydrophobicContact CD2-CG2 4.32Å; L62-M256 HydrophobicContact CD2-CG 3.98Å; L62-Y296 HydrophobicContact CD1-CD1 3.68Å; L62-Y296 HydrophobicContact CD1-CD2 3.5Å; L62-Y296 HydrophobicContact CD1-CE1 4.11Å; L62-Y296 HydrophobicContact CD1-CE2 3.98Å; L62-Y296 HydrophobicContact CD1-CG 3.29Å; L62-A300 HydrophobicContact CB-CB 4.01Å
63	A	95.9	Very high	92.5	Very high	0 Å²	0	10.6 Å²	10.6	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-62.7	-38.7	172.6	0	0	0	0	0	111.3	M66 A67 V311 L315	A63-M66 PolarHBondContact O-N 3.05Å; A63-A67 PolarHBondContact O-N 3.48Å; A63-V311 HydrophobicContact CB-CG1 3.9Å; A63-L315 HydrophobicContact CB-CD1 3.89Å; A63-L315 HydrophobicContact CB-CD2 4.23Å; A63-L315 HydrophobicContact CB-CG 4.44Å
64	Y	94.2	Very high	92.8	Very high	15 Å²	15	9.1 Å²	9.1	6%	0.059	6%	0.059	C	C	.	.	H	α-helix	trans	-65	-40.3	174.2	176.3	-93.6	0	0	0	111.9	G61 L62 M66 A67 S68 Q312 R392	G61-Y64 WeakPolarHBondContact O-CB 3.41Å; G61-Y64 PolarHBondContact O-N 3.24Å; L62-Y64 VanDerWaalsContact C-N 3.28Å; L62-Y64 PolarHBondContact O-N 3.17Å; Y64-M66 VanDerWaalsContact C-N 3.32Å; Y64-M66 PolarHBondContact O-N 3.33Å; Y64-A67 PolarHBondContact O-N 2.95Å; Y64-S68 WeakPolarHBondContact O-CB 3.36Å; Y64-S68 PolarHBondContact O-N 3.17Å; Y64-S68 PolarHBondContact O-OG 3.14Å; Y64-Q312 WeakPolarHBondContact CB-O 3.38Å; Y64-R392 HydrophobicContact CD1-CG 4.13Å; Y64-R392 HydrophobicContact CE1-CG 4.16Å; Y64-R392 VanDerWaalsContact CE2-NH1 3.27Å; Y64-R392 VanDerWaalsContact CZ-CD 3.45Å; Y64-R392 PolarHBondContact OH-NH1 3.48Å
65	A	94.8	Very high	93	Very high	1 Å²	1	10.4 Å²	10.4	1%	0.008	7%	0.068	C	C	.	.	H	α-helix	trans	-61.4	-40.4	173.8	0	0	0	0	0	111.6	G61 L62 S68 T69 F74 A252	G61-A65 PolarHBondContact O-N 3.43Å; G61-A65 VanDerWaalsContact O-N 3.08Å; L62-A65 WeakPolarHBondContact O-CB 3.44Å; L62-A65 PolarHBondContact O-N 3.36Å; A65-S68 PolarHBondContact O-N 2.84Å; A65-T69 PolarHBondContact O-N 2.72Å; A65-T69 VanDerWaalsContact O-N 3.12Å; A65-T69 PolarHBondContact O-OG1 3.26Å; A65-F74 HydrophobicContact CB-CD2 4.21Å; A65-F74 HydrophobicContact CB-CE2 4.09Å; A65-A252 HydrophobicContact CB-CB 3.97Å
66	M	95.7	Very high	93.4	Very high	0 Å²	0	16 Å²	16	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-65.6	-43.6	174.2	-173.3	179.4	-71.4	0	0	112.1	L62 A63 Y64 S68 T69 G70 I71 F74 A300 L301 Y304	L62-M66 PolarHBondContact O-N 3.2Å; A63-M66 PolarHBondContact O-N 3.05Å; Y64-M66 VanDerWaalsContact C-N 3.32Å; Y64-M66 PolarHBondContact O-N 3.33Å; M66-S68 PolarHBondContact O-N 3.19Å; M66-T69 PolarHBondContact O-N 3.44Å; M66-G70 WeakPolarHBondContact O-CA 3.43Å; M66-G70 PolarHBondContact O-N 3.45Å; M66-I71 HydrophobicContact SD-CG1 4.2Å; M66-F74 HydrophobicContact CB-CB 4.01Å; M66-F74 HydrophobicContact CB-CD1 4.32Å; M66-F74 HydrophobicContact CB-CD2 3.61Å; M66-F74 HydrophobicContact CB-CE2 4.12Å; M66-F74 HydrophobicContact CB-CG 3.72Å; M66-F74 HydrophobicContact CE-CB 4.24Å; M66-F74 HydrophobicContact CE-CD1 3.15Å; M66-F74 HydrophobicContact CE-CE1 3.47Å; M66-F74 VanDerWaalsContact CE-CE1 3.47Å; M66-F74 HydrophobicContact CE-CG 3.74Å; M66-F74 HydrophobicContact CE-CZ 4.29Å; M66-F74 HydrophobicContact CG-CB 3.84Å; M66-F74 HydrophobicContact CG-CD1 4.35Å; M66-F74 HydrophobicContact CG-CD2 4.34Å; M66-F74 HydrophobicContact CG-CG 3.93Å; M66-A300 HydrophobicContact CB-CB 4.5Å; M66-A300 HydrophobicContact CE-CB 3.84Å; M66-L301 HydrophobicContact CE-CB 4.05Å; M66-L301 HydrophobicContact CE-CD1 4.4Å; M66-L301 VanDerWaalsContact SD-CA 3.57Å; M66-L301 HydrophobicContact SD-CB 4.38Å; M66-L301 HydrophobicContact SD-CD1 4.11Å; M66-Y304 HydrophobicContact CB-CG 4.47Å; M66-Y304 HydrophobicContact CG-CD1 4.06Å; M66-Y304 HydrophobicContact CG-CG 3.96Å; M66-Y304 HydrophobicContact SD-CD1 3.73Å; M66-Y304 HydrophobicContact SD-CG 3.89Å
67	A	93.4	Very high	94.1	Very high	17 Å²	17	17 Å²	17	14%	0.14	10%	0.1	C	C	.	.	H	α-helix	trans	-58.8	-31	175.3	0	0	0	0	0	112.9	A63 Y64 Y304 V311	A63-A67 PolarHBondContact O-N 3.48Å; Y64-A67 PolarHBondContact O-N 2.95Å; A67-Y304 HydrophobicContact CB-CD2 3.74Å; A67-Y304 HydrophobicContact CB-CE2 4.03Å; A67-V311 HydrophobicContact CB-CB 3.85Å; A67-V311 HydrophobicContact CB-CG2 3.88Å
68	S	92.1	Very high	94.5	Very high	8 Å²	8	16.9 Å²	16.9	6%	0.056	10%	0.099	C	C	.	.	H	α-helix	trans	-85.8	-21.1	-178.1	-57.3	0	0	0	0	114.2	Y64 A65 M66 S249	Y64-S68 WeakPolarHBondContact O-CB 3.36Å; Y64-S68 PolarHBondContact O-N 3.17Å; Y64-S68 PolarHBondContact O-OG 3.14Å; A65-S68 PolarHBondContact O-N 2.84Å; M66-S68 PolarHBondContact O-N 3.19Å; S68-S249 WeakPolarHBondContact O-CB 3.49Å
69	T	94.3	Very high	95	Very high	6 Å²	6	20.9 Å²	20.9	4%	0.037	12%	0.122	C	C	.	.	H	α-helix	trans	-114.9	-16.4	-175.2	50.9	0	0	0	0	113.9	A65 M66 F74 L77 I244 A252	A65-T69 PolarHBondContact O-N 2.72Å; A65-T69 VanDerWaalsContact O-N 3.12Å; A65-T69 PolarHBondContact O-OG1 3.26Å; M66-T69 PolarHBondContact O-N 3.44Å; T69-F74 WeakPolarHBondContact OG1-CB 3.47Å; T69-F74 PolarHBondContact OG1-N 2.83Å; T69-L77 HydrophobicContact CG2-CD1 3.97Å; T69-I244 CarbonylContact C-O 3.56Å; T69-I244 WeakPolarHBondContact CA-O 3.26Å; T69-I244 PolarHBondContact O-N 3.47Å; T69-A252 HydrophobicContact CG2-CB 3.52Å
70	G	94.2	Very high	95.2	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	14%	0.138	C	C	.	.			trans	78.9	165	-168.2	0	0	0	0	0	112.7	M66 V72 G73 F74 K241 L242	M66-G70 WeakPolarHBondContact O-CA 3.43Å; M66-G70 PolarHBondContact O-N 3.45Å; G70-V72 PolarHBondContact O-N 2.76Å; G70-G73 PolarHBondContact O-N 3.08Å; G70-F74 VanDerWaalsContact O-CB 3.22Å; G70-F74 WeakPolarHBondContact O-CB 3.42Å; G70-F74 PolarHBondContact O-N 3.36Å; G70-K241 CarbonylContact C-O 3.55Å; G70-K241 WeakPolarHBondContact CA-O 3.26Å; G70-L242 CarbonylContact C-O 3.52Å
71	I	95.6	Very high	95.4	Very high	31 Å²	31	23.7 Å²	23.7	16%	0.159	14%	0.137	C	C	.	.	H	α-helix	trans	-61.5	-47.5	-173.5	-60.6	175.4	0	0	0	111.9	M66 S75 P240 K241 L242 L301 Y304 L305	M66-I71 HydrophobicContact SD-CG1 4.2Å; I71-S75 WeakPolarHBondContact O-CB 3.32Å; I71-S75 PolarHBondContact O-N 2.96Å; I71-S75 PolarHBondContact O-OG 3.49Å; I71-P240 HydrophobicContact CD1-CB 3.75Å; I71-K241 PolarHBondContact N-O 2.98Å; I71-L242 PolarHBondContact N-O 3.34Å; I71-L301 HydrophobicContact CD1-CD1 4.18Å; I71-L301 HydrophobicContact CG1-CD1 4.39Å; I71-L301 HydrophobicContact CG2-CD1 4.18Å; I71-Y304 HydrophobicContact CD1-CD1 4.29Å; I71-Y304 HydrophobicContact CD1-CE1 3.97Å; I71-Y304 HydrophobicContact CG1-CD1 3.92Å; I71-Y304 HydrophobicContact CG1-CE1 3.68Å; I71-L305 HydrophobicContact CD1-CD2 4.36Å
72	V	95.7	Very high	95.7	Very high	80 Å²	80	24.1 Å²	24.1	49%	0.485	14%	0.14	S	C	.	.	H	α-helix	trans	-69.4	-44.5	-178.2	179.6	0	0	0	0	110.2	G70 S75 L76 L242	G70-V72 PolarHBondContact O-N 2.76Å; V72-S75 PolarHBondContact O-N 3.2Å; V72-L76 WeakPolarHBondContact O-CB 3.31Å; V72-L76 PolarHBondContact O-N 3.38Å; V72-L242 WeakPolarHBondContact CB-O 3.38Å; V72-L242 HydrophobicContact CG2-CB 4.04Å; V72-L242 HydrophobicContact CG2-CD2 4.1Å; V72-L242 PolarHBondContact N-O 3.3Å
73	G	94.9	Very high	95.8	Very high	5 Å²	5	25.9 Å²	25.9	5%	0.052	16%	0.158	C	C	.	.	H	α-helix	trans	-59.1	-48.5	177.1	0	0	0	0	0	111.9	G70 S75 L76 L77	G70-G73 PolarHBondContact O-N 3.08Å; G73-S75 PolarHBondContact O-N 3.47Å; G73-L76 PolarHBondContact O-N 2.97Å; G73-L77 WeakPolarHBondContact O-CB 3.22Å; G73-L77 VanDerWaalsContact O-CG 3.28Å; G73-L77 WeakPolarHBondContact O-CG 3.38Å; G73-L77 PolarHBondContact O-N 3.5Å
74	F	96.7	Very high	95.9	Very high	0 Å²	0	26.5 Å²	26.5	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-59.5	-47.3	175.1	-179.4	-91	0	0	0	112.3	L62 A65 M66 T69 G70 L76 L77 L78 M256 F297 A300	L62-F74 HydrophobicContact CB-CE2 4.23Å; L62-F74 HydrophobicContact CB-CZ 4.17Å; L62-F74 HydrophobicContact CD2-CE2 4.29Å; L62-F74 HydrophobicContact CD2-CZ 4.48Å; L62-F74 VanDerWaalsContact O-CE2 3.28Å; L62-F74 WeakPolarHBondContact O-CE2 3.43Å; A65-F74 HydrophobicContact CB-CD2 4.21Å; A65-F74 HydrophobicContact CB-CE2 4.09Å; M66-F74 HydrophobicContact CB-CB 4.01Å; M66-F74 HydrophobicContact CB-CD1 4.32Å; M66-F74 HydrophobicContact CB-CD2 3.61Å; M66-F74 HydrophobicContact CB-CE2 4.12Å; M66-F74 HydrophobicContact CB-CG 3.72Å; M66-F74 HydrophobicContact CE-CB 4.24Å; M66-F74 HydrophobicContact CE-CD1 3.15Å; M66-F74 HydrophobicContact CE-CE1 3.47Å; M66-F74 VanDerWaalsContact CE-CE1 3.47Å; M66-F74 HydrophobicContact CE-CG 3.74Å; M66-F74 HydrophobicContact CE-CZ 4.29Å; M66-F74 HydrophobicContact CG-CB 3.84Å; M66-F74 HydrophobicContact CG-CD1 4.35Å; M66-F74 HydrophobicContact CG-CD2 4.34Å; M66-F74 HydrophobicContact CG-CG 3.93Å; T69-F74 WeakPolarHBondContact OG1-CB 3.47Å; T69-F74 PolarHBondContact OG1-N 2.83Å; G70-F74 VanDerWaalsContact O-CB 3.22Å; G70-F74 WeakPolarHBondContact O-CB 3.42Å; G70-F74 PolarHBondContact O-N 3.36Å; F74-L76 VanDerWaalsContact C-N 3.35Å; F74-L76 PolarHBondContact O-N 3.44Å; F74-L77 PolarHBondContact O-N 3.34Å; F74-L78 HydrophobicContact CE1-CB 4.31Å; F74-L78 HydrophobicContact CE1-CD1 4.23Å; F74-L78 HydrophobicContact CE1-CD2 3.87Å; F74-L78 HydrophobicContact CE1-CG 4.38Å; F74-L78 HydrophobicContact CZ-CD1 3.96Å; F74-L78 HydrophobicContact CZ-CD2 4.35Å; F74-L78 VanDerWaalsContact O-CB 3.3Å; F74-L78 WeakPolarHBondContact O-CB 3.42Å; F74-L78 PolarHBondContact O-N 3.49Å; F74-M256 HydrophobicContact CD2-CE 3.19Å; F74-M256 HydrophobicContact CE2-CE 3.33Å; F74-M256 HydrophobicContact CG-CE 3.9Å; F74-M256 HydrophobicContact CZ-CE 4.12Å; F74-F297 HydrophobicContact CE1-CD2 4.37Å; F74-A300 HydrophobicContact CE1-CB 3.72Å; F74-A300 HydrophobicContact CE2-CB 4.11Å; F74-A300 HydrophobicContact CZ-CB 3.39Å
75	S	97.1	Very high	96	Very high	31 Å²	31	25.8 Å²	25.8	22%	0.217	16%	0.159	C	C	.	.	H	α-helix	trans	-59.5	-46.1	-178.2	-57.2	0	0	0	0	111.4	I71 V72 G73 L78 V79 F297	I71-S75 WeakPolarHBondContact O-CB 3.32Å; I71-S75 PolarHBondContact O-N 2.96Å; I71-S75 PolarHBondContact O-OG 3.49Å; V72-S75 PolarHBondContact O-N 3.2Å; G73-S75 PolarHBondContact O-N 3.47Å; S75-L78 PolarHBondContact O-N 3.48Å; S75-V79 WeakPolarHBondContact O-CG2 3.48Å; S75-V79 PolarHBondContact O-N 2.99Å; S75-F297 WeakPolarHBondContact OG-CE2 3.43Å
76	L	96.8	Very high	96.1	Very high	120 Å²	120	27.9 Å²	27.9	63%	0.628	17%	0.169	S	C	*	.	H	α-helix	trans	-62.1	-46.7	177.6	-178.2	68.3	0	0	0	111.5	V72 G73 F74 V79 L80	V72-L76 WeakPolarHBondContact O-CB 3.31Å; V72-L76 PolarHBondContact O-N 3.38Å; G73-L76 PolarHBondContact O-N 2.97Å; F74-L76 VanDerWaalsContact C-N 3.35Å; F74-L76 PolarHBondContact O-N 3.44Å; L76-V79 PolarHBondContact O-N 2.93Å; L76-L80 WeakPolarHBondContact O-CB 3.27Å; L76-L80 PolarHBondContact O-N 3.29Å
77	L	95.9	Very high	96.2	Very high	34 Å²	34	30 Å²	30	18%	0.178	18%	0.178	C	C	.	.	H	α-helix	trans	-65.5	-39.1	179.1	-70.2	175.7	0	0	0	112.1	T69 G73 F74 L80 V81 I253 M256	T69-L77 HydrophobicContact CG2-CD1 3.97Å; G73-L77 WeakPolarHBondContact O-CB 3.22Å; G73-L77 VanDerWaalsContact O-CG 3.28Å; G73-L77 WeakPolarHBondContact O-CG 3.38Å; G73-L77 PolarHBondContact O-N 3.5Å; F74-L77 PolarHBondContact O-N 3.34Å; L77-L80 PolarHBondContact O-N 2.98Å; L77-V81 WeakPolarHBondContact O-CB 3.22Å; L77-V81 WeakPolarHBondContact O-CG2 3.44Å; L77-V81 PolarHBondContact O-N 3.43Å; L77-I253 HydrophobicContact CD1-CG1 4.02Å; L77-I253 HydrophobicContact CD2-CD1 3.86Å; L77-I253 HydrophobicContact CD2-CG1 3.91Å; L77-M256 HydrophobicContact CB-CE 3.87Å; L77-M256 HydrophobicContact CB-SD 3.63Å
78	L	97.3	Very high	96.4	Very high	0 Å²	0	29.2 Å²	29.2	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-64.6	-43.6	178.2	-163.6	78.6	0	0	0	111	F74 S75 S82 M256 F260 F293 F297	F74-L78 HydrophobicContact CE1-CB 4.31Å; F74-L78 HydrophobicContact CE1-CD1 4.23Å; F74-L78 HydrophobicContact CE1-CD2 3.87Å; F74-L78 HydrophobicContact CE1-CG 4.38Å; F74-L78 HydrophobicContact CZ-CD1 3.96Å; F74-L78 HydrophobicContact CZ-CD2 4.35Å; F74-L78 VanDerWaalsContact O-CB 3.3Å; F74-L78 WeakPolarHBondContact O-CB 3.42Å; F74-L78 PolarHBondContact O-N 3.49Å; S75-L78 PolarHBondContact O-N 3.48Å; L78-S82 VanDerWaalsContact O-CB 3.28Å; L78-S82 WeakPolarHBondContact O-CB 3.27Å; L78-S82 PolarHBondContact O-N 2.74Å; L78-S82 PolarHBondContact O-OG 2.95Å; L78-M256 HydrophobicContact CB-CE 4.46Å; L78-M256 HydrophobicContact CD1-CE 4.42Å; L78-M256 HydrophobicContact CD1-CG 4.36Å; L78-M256 HydrophobicContact CD1-SD 4.38Å; L78-F260 HydrophobicContact CD1-CE2 3.57Å; L78-F260 HydrophobicContact CD1-CZ 4.09Å; L78-F260 HydrophobicContact CG-CE2 4.16Å; L78-F260 HydrophobicContact CG-CZ 4.39Å; L78-F293 HydrophobicContact CB-CE2 4.05Å; L78-F293 HydrophobicContact CD2-CD2 3.67Å; L78-F293 HydrophobicContact CD2-CE2 3.5Å; L78-F293 HydrophobicContact CD2-CG 4.37Å; L78-F293 HydrophobicContact CD2-CZ 4.06Å; L78-F293 HydrophobicContact CG-CD2 3.77Å; L78-F293 HydrophobicContact CG-CE2 3.66Å; L78-F297 HydrophobicContact CD2-CB 3.86Å; L78-F297 HydrophobicContact CD2-CD2 4.28Å
79	V	98.1	Very high	96.7	Very high	84 Å²	84	28.9 Å²	28.9	51%	0.509	17%	0.168	S	C	.	.	H	α-helix	trans	-63.7	-44.7	174.8	171.2	0	0	0	0	110.6	S75 L76 S82 G83 F293	S75-V79 WeakPolarHBondContact O-CG2 3.48Å; S75-V79 PolarHBondContact O-N 2.99Å; L76-V79 PolarHBondContact O-N 2.93Å; V79-S82 PolarHBondContact O-OG 3.38Å; V79-G83 PolarHBondContact O-N 3.42Å; V79-F293 HydrophobicContact CB-CE2 4.49Å; V79-F293 HydrophobicContact CG2-CE2 3.73Å; V79-F293 HydrophobicContact CG2-CZ 3.7Å
80	L	96.8	Very high	96.8	Very high	64 Å²	64	31.1 Å²	31.1	34%	0.335	18%	0.178	S	C	.	.	H	α-helix	trans	-60.6	-52.8	178.5	178.1	63.8	0	0	0	111.9	L76 L77 G83 L84 F437	L76-L80 WeakPolarHBondContact O-CB 3.27Å; L76-L80 PolarHBondContact O-N 3.29Å; L77-L80 PolarHBondContact O-N 2.98Å; L80-G83 PolarHBondContact O-N 3.02Å; L80-L84 HydrophobicContact CD1-CD1 3.97Å; L80-L84 HydrophobicContact CD1-CG 4.24Å; L80-L84 HydrophobicContact CG-CD1 4.04Å; L80-L84 WeakPolarHBondContact O-CB 3.4Å; L80-L84 VanDerWaalsContact O-CG 3.23Å; L80-L84 WeakPolarHBondContact O-CG 3.39Å; L80-L84 PolarHBondContact O-N 2.97Å; L80-F437 HydrophobicContact CD2-CE2 3.92Å; L80-F437 HydrophobicContact CD2-CZ 4Å; L80-F437 HydrophobicContact CG-CZ 4.49Å
81	V	97.1	Very high	96.9	Very high	0 Å²	0	31.1 Å²	31.1	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-66.7	-41.5	-176.7	174	0	0	0	0	111.4	L77 L84 A85 I253 M256 F260 F408	L77-V81 WeakPolarHBondContact O-CB 3.22Å; L77-V81 WeakPolarHBondContact O-CG2 3.44Å; L77-V81 PolarHBondContact O-N 3.43Å; V81-L84 PolarHBondContact O-N 3.34Å; V81-A85 WeakPolarHBondContact O-CB 3.34Å; V81-A85 PolarHBondContact O-N 2.97Å; V81-I253 HydrophobicContact CG2-CG2 4.28Å; V81-M256 HydrophobicContact CB-CB 4.29Å; V81-M256 HydrophobicContact CG1-CB 4.09Å; V81-M256 HydrophobicContact CG2-CB 4.14Å; V81-M256 HydrophobicContact CG2-SD 4.48Å; V81-F260 HydrophobicContact CG1-CB 4.34Å; V81-F260 HydrophobicContact CG1-CD2 3.96Å; V81-F408 HydrophobicContact CG1-CZ 4.47Å
82	S	97.3	Very high	96.9	Very high	11 Å²	11	29.6 Å²	29.6	8%	0.077	17%	0.171	C	C	.	.	H	α-helix	trans	-67.7	-39.6	177.2	59.2	0	0	0	0	112.7	L78 V79 A85 L86	L78-S82 VanDerWaalsContact O-CB 3.28Å; L78-S82 WeakPolarHBondContact O-CB 3.27Å; L78-S82 PolarHBondContact O-N 2.74Å; L78-S82 PolarHBondContact O-OG 2.95Å; V79-S82 PolarHBondContact O-OG 3.38Å; S82-A85 PolarHBondContact O-N 3.31Å; S82-L86 PolarHBondContact O-N 2.86Å
83	G	97.8	Very high	96.9	Very high	37 Å²	37	25.8 Å²	25.8	38%	0.381	15%	0.148	S	C	.	.	H	α-helix	trans	-63.2	-43.8	173.9	0	0	0	0	0	112.3	V79 L80 L86 Y87	V79-G83 PolarHBondContact O-N 3.42Å; L80-G83 PolarHBondContact O-N 3.02Å; G83-L86 PolarHBondContact O-N 2.9Å; G83-Y87 WeakPolarHBondContact O-CB 3.45Å; G83-Y87 PolarHBondContact O-N 3.28Å
84	L	97.2	Very high	96.9	Very high	13 Å²	13	26 Å²	26	7%	0.068	15%	0.148	C	C	.	.	H	α-helix	trans	-64.7	-38.5	174.5	-72.4	173.9	0	0	0	112.4	L80 V81 Y87 S88 F408 F433 L434 F437	L80-L84 HydrophobicContact CD1-CD1 3.97Å; L80-L84 HydrophobicContact CD1-CG 4.24Å; L80-L84 HydrophobicContact CG-CD1 4.04Å; L80-L84 WeakPolarHBondContact O-CB 3.4Å; L80-L84 VanDerWaalsContact O-CG 3.23Å; L80-L84 WeakPolarHBondContact O-CG 3.39Å; L80-L84 PolarHBondContact O-N 2.97Å; V81-L84 PolarHBondContact O-N 3.34Å; L84-Y87 PolarHBondContact O-N 3.04Å; L84-S88 VanDerWaalsContact O-CB 3.25Å; L84-S88 WeakPolarHBondContact O-CB 3.44Å; L84-S88 PolarHBondContact O-N 2.98Å; L84-F408 HydrophobicContact CB-CD1 4.16Å; L84-F408 HydrophobicContact CB-CE1 3.61Å; L84-F408 HydrophobicContact CD1-CD1 4.29Å; L84-F408 HydrophobicContact CD1-CE1 3.71Å; L84-F408 HydrophobicContact CD1-CZ 4.47Å; L84-F408 HydrophobicContact CG-CE1 4.29Å; L84-F433 HydrophobicContact CD2-CD1 4.26Å; L84-F433 HydrophobicContact CD2-CE1 3.89Å; L84-L434 HydrophobicContact CD2-CD1 4.31Å; L84-F437 HydrophobicContact CD1-CD1 3.58Å; L84-F437 HydrophobicContact CD1-CE1 3.44Å; L84-F437 VanDerWaalsContact CD1-CE1 3.44Å; L84-F437 HydrophobicContact CD1-CE2 4.44Å; L84-F437 HydrophobicContact CD1-CG 4.15Å; L84-F437 HydrophobicContact CD1-CZ 3.91Å
85	A	97.3	Very high	96.8	Very high	0 Å²	0	26 Å²	26	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-61.7	-45.3	174.9	0	0	0	0	0	111.7	V81 S82 Y87 S88 I89 F260 I289 L407	V81-A85 WeakPolarHBondContact O-CB 3.34Å; V81-A85 PolarHBondContact O-N 2.97Å; S82-A85 PolarHBondContact O-N 3.31Å; A85-Y87 VanDerWaalsContact C-N 3.35Å; A85-Y87 PolarHBondContact O-N 3.21Å; A85-S88 PolarHBondContact O-N 3.31Å; A85-I89 VanDerWaalsContact O-CG1 3.32Å; A85-I89 WeakPolarHBondContact O-CG1 3.26Å; A85-I89 PolarHBondContact O-N 3.34Å; A85-F260 HydrophobicContact CB-CB 4.38Å; A85-I289 HydrophobicContact CB-CD1 4.24Å; A85-L407 HydrophobicContact CB-CD1 4.33Å; A85-L407 HydrophobicContact CB-CD2 3.97Å; A85-L407 HydrophobicContact CB-CG 4.38Å
86	L	97.4	Very high	96.6	Very high	45 Å²	45	24.7 Å²	24.7	24%	0.236	14%	0.139	C	C	.	.	H	α-helix	trans	-61.2	-43.4	175.8	-80.6	168.4	0	0	0	112.5	S82 G83 I89 H90 N286 I289	S82-L86 PolarHBondContact O-N 2.86Å; G83-L86 PolarHBondContact O-N 2.9Å; L86-I89 PolarHBondContact O-N 3.49Å; L86-H90 PolarHBondContact O-N 3.32Å; L86-N286 WeakPolarHBondContact CD2-OD1 3.31Å; L86-I289 HydrophobicContact CD1-CB 4.45Å; L86-I289 HydrophobicContact CD1-CG2 4Å; L86-I289 HydrophobicContact CD2-CB 4.01Å; L86-I289 HydrophobicContact CD2-CD1 3.6Å; L86-I289 HydrophobicContact CD2-CG1 4.28Å; L86-I289 HydrophobicContact CD2-CG2 4.36Å; L86-I289 HydrophobicContact CG-CB 4.12Å; L86-I289 HydrophobicContact CG-CD1 3.72Å; L86-I289 HydrophobicContact CG-CG1 4.5Å; L86-I289 HydrophobicContact CG-CG2 3.91Å
87	Y	97.6	Very high	96.4	Very high	45 Å²	45	23.9 Å²	23.9	18%	0.176	14%	0.135	C	C	.	.	H	α-helix	trans	-66.4	-41.4	178.5	-178.7	-108.8	0	0	0	111.9	G83 L84 A85 I89 H90 L91 D427 G430 L434	G83-Y87 WeakPolarHBondContact O-CB 3.45Å; G83-Y87 PolarHBondContact O-N 3.28Å; L84-Y87 PolarHBondContact O-N 3.04Å; A85-Y87 VanDerWaalsContact C-N 3.35Å; A85-Y87 PolarHBondContact O-N 3.21Å; Y87-I89 PolarHBondContact O-N 3.02Å; Y87-H90 VanDerWaalsContact O-CB 3.29Å; Y87-H90 WeakPolarHBondContact O-CB 3.45Å; Y87-H90 PolarHBondContact O-N 3.43Å; Y87-H90 VanDerWaalsContact O-N 3.1Å; Y87-L91 HydrophobicContact CD1-CD1 4.35Å; Y87-L91 HydrophobicContact CE1-CD1 3.77Å; Y87-L91 HydrophobicContact CE1-CD2 4.41Å; Y87-L91 HydrophobicContact CE1-CG 4.13Å; Y87-L91 HydrophobicContact CE2-CD2 4.4Å; Y87-L91 PolarHBondContact O-N 3.05Å; Y87-D427 VanDerWaalsContact OH-CA 3.28Å; Y87-D427 WeakPolarHBondContact OH-CA 3.33Å; Y87-D427 PolarHBondContact OH-O 3.45Å; Y87-G430 VanDerWaalsContact OH-CA 3.28Å; Y87-G430 WeakPolarHBondContact OH-CA 3.44Å; Y87-L434 HydrophobicContact CD1-CD1 3.77Å; Y87-L434 HydrophobicContact CE1-CD1 4.38Å
88	S	97.5	Very high	96.2	Very high	0 Å²	0	26.4 Å²	26.4	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-60.4	-43.7	175.3	-165.6	0	0	0	0	112.8	L84 A85 H90 L91 L92 H263 L407 P411	L84-S88 VanDerWaalsContact O-CB 3.25Å; L84-S88 WeakPolarHBondContact O-CB 3.44Å; L84-S88 PolarHBondContact O-N 2.98Å; A85-S88 PolarHBondContact O-N 3.31Å; S88-H90 VanDerWaalsContact C-N 3.31Å; S88-H90 PolarHBondContact O-N 3.12Å; S88-L91 PolarHBondContact O-N 2.71Å; S88-L92 PolarHBondContact O-N 2.93Å; S88-H263 VanDerWaalsContact CB-NE2 3.34Å; S88-H263 WeakPolarHBondContact CB-NE2 3.47Å; S88-H263 PolarHBondContact OG-NE2 3.49Å; S88-L407 WeakPolarHBondContact CB-O 3.2Å; S88-L407 PolarHBondContact OG-O 2.97Å; S88-P411 WeakPolarHBondContact OG-CB 3.14Å; S88-P411 WeakPolarHBondContact OG-CG 3.33Å
89	I	97.2	Very high	96	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-59.1	-43.3	171.9	-74.2	166	0	0	0	111.1	A85 L86 Y87 L91 L92 L93 I266 A285 I289	A85-I89 VanDerWaalsContact O-CG1 3.32Å; A85-I89 WeakPolarHBondContact O-CG1 3.26Å; A85-I89 PolarHBondContact O-N 3.34Å; L86-I89 PolarHBondContact O-N 3.49Å; Y87-I89 PolarHBondContact O-N 3.02Å; I89-L91 VanDerWaalsContact C-N 3.33Å; I89-L91 PolarHBondContact O-N 3.37Å; I89-L92 PolarHBondContact O-N 3.41Å; I89-L93 HydrophobicContact CG2-CD1 3.76Å; I89-L93 HydrophobicContact CG2-CG 4.16Å; I89-L93 WeakPolarHBondContact O-CG 3.49Å; I89-L93 PolarHBondContact O-N 3.49Å; I89-I266 HydrophobicContact CB-CD1 3.95Å; I89-I266 HydrophobicContact CD1-CD1 3.77Å; I89-I266 HydrophobicContact CG1-CD1 3.57Å; I89-I266 HydrophobicContact CG2-CD1 3.22Å; I89-A285 HydrophobicContact CD1-CB 4.23Å; I89-A285 HydrophobicContact CG2-CB 3.82Å; I89-I289 HydrophobicContact CD1-CD1 3.56Å
90	H	96.6	Very high	95.6	Very high	53 Å²	53	27 Å²	27	25%	0.245	16%	0.161	C	C	.	.	H	α-helix	trans	-59.3	-44.5	178.3	-176.1	75.5	0	0	0	112.2	L86 Y87 S88 T94 K278 Q282	L86-H90 PolarHBondContact O-N 3.32Å; Y87-H90 VanDerWaalsContact O-CB 3.29Å; Y87-H90 WeakPolarHBondContact O-CB 3.45Å; Y87-H90 PolarHBondContact O-N 3.43Å; Y87-H90 VanDerWaalsContact O-N 3.1Å; S88-H90 VanDerWaalsContact C-N 3.31Å; S88-H90 PolarHBondContact O-N 3.12Å; H90-T94 WeakPolarHBondContact O-CB 3.47Å; H90-T94 PolarHBondContact O-N 3.45Å; H90-T94 PolarHBondContact O-OG1 3.2Å; H90-K278 PolarHBondContact CE1-NZ 3.18Å; H90-Q282 PolarHBondContact ND1-OE1 3.01Å; H90-Q282 VanDerWaalsContact ND1-OE1 3.08Å
91	L	96.3	Very high	95.4	Very high	0 Å²	0	25.4 Å²	25.4	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-60.3	-47.2	175.1	-64.3	-178.3	0	0	0	110.7	Y87 S88 I89 L93 T94 L95 Y415 D427 A431	Y87-L91 HydrophobicContact CD1-CD1 4.35Å; Y87-L91 HydrophobicContact CE1-CD1 3.77Å; Y87-L91 HydrophobicContact CE1-CD2 4.41Å; Y87-L91 HydrophobicContact CE1-CG 4.13Å; Y87-L91 HydrophobicContact CE2-CD2 4.4Å; Y87-L91 PolarHBondContact O-N 3.05Å; S88-L91 PolarHBondContact O-N 2.71Å; I89-L91 VanDerWaalsContact C-N 3.33Å; I89-L91 PolarHBondContact O-N 3.37Å; L91-L93 PolarHBondContact O-N 3.07Å; L91-T94 WeakPolarHBondContact O-CB 3.33Å; L91-T94 PolarHBondContact O-N 3.36Å; L91-L95 WeakPolarHBondContact O-CG 3.47Å; L91-L95 PolarHBondContact O-N 2.86Å; L91-Y415 HydrophobicContact CB-CD2 4.24Å; L91-Y415 HydrophobicContact CB-CG 4.45Å; L91-Y415 HydrophobicContact CD1-CG 4.48Å; L91-Y415 HydrophobicContact CD2-CD1 4.09Å; L91-Y415 HydrophobicContact CD2-CD2 3.72Å; L91-Y415 HydrophobicContact CD2-CE1 4.32Å; L91-Y415 HydrophobicContact CD2-CE2 3.97Å; L91-Y415 HydrophobicContact CD2-CG 3.78Å; L91-Y415 HydrophobicContact CG-CD2 4.5Å; L91-Y415 HydrophobicContact CG-CG 4.46Å; L91-D427 HydrophobicContact CD2-CB 4.23Å; L91-A431 HydrophobicContact CD1-CB 3.92Å
92	L	95.9	Very high	94.9	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-61.1	-48.3	-179.3	-164	73.5	0	0	0	112	S88 I89 T94 L95 C96 Y104 L107 I266 L267	S88-L92 PolarHBondContact O-N 2.93Å; I89-L92 PolarHBondContact O-N 3.41Å; L92-T94 VanDerWaalsContact C-N 3.28Å; L92-T94 PolarHBondContact O-N 3.44Å; L92-L95 WeakPolarHBondContact O-CB 3.49Å; L92-L95 PolarHBondContact O-N 3.3Å; L92-L95 VanDerWaalsContact O-N 3.12Å; L92-C96 PolarHBondContact O-N 3.4Å; L92-C96 PolarHBondContact O-SG 2.99Å; L92-Y104 HydrophobicContact CD1-CD2 4.11Å; L92-Y104 HydrophobicContact CD1-CE2 3.88Å; L92-Y104 HydrophobicContact CD2-CD2 3.71Å; L92-Y104 HydrophobicContact CD2-CE2 3.65Å; L92-Y104 HydrophobicContact CG-CE2 4.45Å; L92-L107 HydrophobicContact CD1-CD2 3.35Å; L92-L107 HydrophobicContact CG-CD2 4.43Å; L92-I266 HydrophobicContact CD2-CG2 3.88Å; L92-L267 HydrophobicContact CD2-CD1 4.04Å; L92-L267 HydrophobicContact CD2-CD2 3.87Å; L92-L267 HydrophobicContact CD2-CG 3.9Å; L92-L267 HydrophobicContact CG-CD1 4.42Å; L92-L267 HydrophobicContact CG-CD2 4.19Å
93	L	95.5	Very high	94.6	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-64.7	-33.1	178	-67.1	176.9	0	0	0	112.2	I89 L91 L95 C96 D97 Y270 K278 M281 Q282	I89-L93 HydrophobicContact CG2-CD1 3.76Å; I89-L93 HydrophobicContact CG2-CG 4.16Å; I89-L93 WeakPolarHBondContact O-CG 3.49Å; I89-L93 PolarHBondContact O-N 3.49Å; L91-L93 PolarHBondContact O-N 3.07Å; L93-L95 VanDerWaalsContact C-N 3.32Å; L93-C96 PolarHBondContact O-N 3.44Å; L93-D97 WeakPolarHBondContact O-CB 3.41Å; L93-D97 PolarHBondContact O-N 2.89Å; L93-Y270 HydrophobicContact CD2-CG 4.45Å; L93-K278 HydrophobicContact CB-CG 4.16Å; L93-M281 HydrophobicContact CD1-CB 4.1Å; L93-M281 HydrophobicContact CD1-CG 4.01Å; L93-M281 HydrophobicContact CD2-CB 4.24Å; L93-M281 HydrophobicContact CD2-CG 3.78Å; L93-Q282 HydrophobicContact CD1-CB 4.32Å
94	T	94.6	Very high	94.3	Very high	10 Å²	10	27.7 Å²	27.7	6%	0.061	16%	0.156	C	C	.	.	H	α-helix	trans	-63.5	-40.3	173.1	-57.9	0	0	0	0	111.4	H90 L91 L92 D97 Q98 K278 Y415	H90-T94 WeakPolarHBondContact O-CB 3.47Å; H90-T94 PolarHBondContact O-N 3.45Å; H90-T94 PolarHBondContact O-OG1 3.2Å; L91-T94 WeakPolarHBondContact O-CB 3.33Å; L91-T94 PolarHBondContact O-N 3.36Å; L92-T94 VanDerWaalsContact C-N 3.28Å; L92-T94 PolarHBondContact O-N 3.44Å; T94-D97 PolarHBondContact O-N 3.34Å; T94-Q98 VanDerWaalsContact O-CG 3.31Å; T94-Q98 WeakPolarHBondContact O-CG 3.46Å; T94-Q98 PolarHBondContact O-N 3Å; T94-K278 WeakPolarHBondContact OG1-CE 3.35Å; T94-K278 PolarHBondContact OG1-NZ 2.9Å; T94-Y415 HydrophobicContact CG2-CE2 4.18Å
95	L	94.7	Very high	94	Very high	0 Å²	0	28.2 Å²	28.2	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-70	-38.4	177.4	-65.9	172.7	0	0	0	112.3	L91 L92 L93 D97 Q98 T99 L107 F414 Y415 I418	L91-L95 WeakPolarHBondContact O-CG 3.47Å; L91-L95 PolarHBondContact O-N 2.86Å; L92-L95 WeakPolarHBondContact O-CB 3.49Å; L92-L95 PolarHBondContact O-N 3.3Å; L92-L95 VanDerWaalsContact O-N 3.12Å; L93-L95 VanDerWaalsContact C-N 3.32Å; L95-D97 VanDerWaalsContact C-N 3.3Å; L95-D97 PolarHBondContact O-N 3.01Å; L95-Q98 PolarHBondContact O-N 3.14Å; L95-T99 WeakPolarHBondContact O-CB 3.47Å; L95-T99 WeakPolarHBondContact O-CG2 3.47Å; L95-T99 PolarHBondContact O-N 3.46Å; L95-T99 PolarHBondContact O-OG1 3.05Å; L95-L107 HydrophobicContact CB-CD1 3.98Å; L95-L107 HydrophobicContact CB-CD2 4.09Å; L95-L107 HydrophobicContact CD1-CD1 4.46Å; L95-L107 HydrophobicContact CD1-CD2 3.87Å; L95-L107 HydrophobicContact CD1-CG 4.5Å; L95-F414 HydrophobicContact CD1-CB 3.66Å; L95-Y415 HydrophobicContact CD1-CD2 4.49Å; L95-Y415 HydrophobicContact CD2-CD2 4.02Å; L95-Y415 HydrophobicContact CG-CD2 4.13Å; L95-I418 HydrophobicContact CD2-CB 3.84Å; L95-I418 HydrophobicContact CD2-CG2 3.83Å
96	C	93.3	Very high	93.7	Very high	2 Å²	2	32.4 Å²	32.4	1%	0.014	18%	0.178	C	C	.	.	H	α-helix	trans	-59.6	-42.9	173	-64.5	0	0	0	0	111.4	L92 L93 G100 I101 L267 Y270	L92-C96 PolarHBondContact O-N 3.4Å; L92-C96 PolarHBondContact O-SG 2.99Å; L93-C96 PolarHBondContact O-N 3.44Å; C96-G100 VanDerWaalsContact O-CA 3.26Å; C96-G100 WeakPolarHBondContact O-CA 3.33Å; C96-G100 PolarHBondContact O-N 3.18Å; C96-I101 WeakPolarHBondContact CA-O 3.1Å; C96-I101 PolarHBondContact SG-O 2.66Å; C96-L267 WeakPolarHBondContact SG-CD2 3.39Å; C96-Y270 HydrophobicContact CB-CE1 4.41Å
97	D	92.3	Very high	93.6	Very high	103 Å²	103	30.2 Å²	30.2	55%	0.551	17%	0.166	S	C	*	.	H	α-helix	trans	-64.6	-42.2	177.3	-167.3	67	0	0	0	112.3	L93 T94 L95	L93-D97 WeakPolarHBondContact O-CB 3.41Å; L93-D97 PolarHBondContact O-N 2.89Å; T94-D97 PolarHBondContact O-N 3.34Å; L95-D97 VanDerWaalsContact C-N 3.3Å; L95-D97 PolarHBondContact O-N 3.01Å
98	Q	92.8	Very high	93.5	Very high	88 Å²	88	28.1 Å²	28.1	41%	0.411	16%	0.158	S	C	.	.	H	α-helix	trans	-73.6	-34.4	179.7	-72.3	176.6	1.1	0	0	114.1	T94 L95	T94-Q98 VanDerWaalsContact O-CG 3.31Å; T94-Q98 WeakPolarHBondContact O-CG 3.46Å; T94-Q98 PolarHBondContact O-N 3Å; L95-Q98 PolarHBondContact O-N 3.14Å
99	T	93.3	Very high	93.3	Very high	43 Å²	43	31.3 Å²	31.3	26%	0.264	17%	0.173	S	C	.	.	H	α-helix	trans	-104.2	-19.1	-171.9	62.5	0	0	0	0	114.2	L95 I101 I418	L95-T99 WeakPolarHBondContact O-CB 3.47Å; L95-T99 WeakPolarHBondContact O-CG2 3.47Å; L95-T99 PolarHBondContact O-N 3.46Å; L95-T99 PolarHBondContact O-OG1 3.05Å; T99-I101 PolarHBondContact O-N 3.2Å; T99-I101 WeakPolarHBondContact OG1-CB 3.39Å; T99-I101 PolarHBondContact OG1-N 3.29Å; T99-I418 HydrophobicContact CG2-CG2 3.4Å; T99-I418 VanDerWaalsContact CG2-CG2 3.4Å
100	G	90.3	Very high	93.2	Very high	54 Å²	54	37.9 Å²	37.9	56%	0.557	20%	0.202	S	C	*	.			trans	71.1	3.6	-168.3	0	0	0	0	0	114.4	C96	C96-G100 VanDerWaalsContact O-CA 3.26Å; C96-G100 WeakPolarHBondContact O-CA 3.33Å; C96-G100 PolarHBondContact O-N 3.18Å
101	I	91.8	Very high	93.1	Very high	29 Å²	29	36.1 Å²	36.1	15%	0.149	20%	0.196	C	C	.	.			trans	-85	118.6	-179.1	-62.1	173	0	0	0	109.5	C96 T99 E106 L107 K110	C96-I101 WeakPolarHBondContact CA-O 3.1Å; C96-I101 PolarHBondContact SG-O 2.66Å; T99-I101 PolarHBondContact O-N 3.2Å; T99-I101 WeakPolarHBondContact OG1-CB 3.39Å; T99-I101 PolarHBondContact OG1-N 3.29Å; I101-E106 HydrophobicContact CG2-CB 3.42Å; I101-E106 VanDerWaalsContact CG2-CB 3.42Å; I101-L107 HydrophobicContact CG2-CB 4.47Å; I101-K110 HydrophobicContact CD1-CB 3.88Å; I101-K110 HydrophobicContact CD1-CD 4.29Å; I101-K110 HydrophobicContact CD1-CG 4.03Å
102	N	87.3	Confident	93.1	Very high	66 Å²	66	38.9 Å²	38.9	35%	0.353	21%	0.211	S	C	.	.			trans	-111.1	31.5	-177.1	-59.4	-42.6	0	0	0	113	C271	N102-C271 VanDerWaalsContact CB-SG 3.53Å
103	S	89.6	Confident	93	Very high	23 Å²	23	46.7 Å²	46.7	16%	0.161	25%	0.245	C	C	.	.			trans	-137.6	135.2	-179.1	171.3	0	0	0	0	110.1	E105 E106 L107	S103-E105 PolarHBondContact OG-OE2 3.26Å; S103-E106 PolarHBondContact O-N 2.92Å; S103-L107 PolarHBondContact O-N 3.18Å
104	Y	91	Very high	92.8	Very high	7 Å²	7	54.1 Å²	54.1	3%	0.027	28%	0.277	C	S	.	.	H	α-helix	trans	-71.2	-38.9	-172.9	-155	-69.7	0	0	0	109.8	L92 L107 G108 V120 H263 L267 L406 F410 P411 F414	L92-Y104 HydrophobicContact CD1-CD2 4.11Å; L92-Y104 HydrophobicContact CD1-CE2 3.88Å; L92-Y104 HydrophobicContact CD2-CD2 3.71Å; L92-Y104 HydrophobicContact CD2-CE2 3.65Å; L92-Y104 HydrophobicContact CG-CE2 4.45Å; Y104-L107 PolarHBondContact O-N 2.92Å; Y104-G108 PolarHBondContact O-N 3.16Å; Y104-G108 VanDerWaalsContact O-N 3.09Å; Y104-V120 HydrophobicContact CD1-CG1 3.41Å; Y104-V120 VanDerWaalsContact CD1-CG1 3.41Å; Y104-V120 HydrophobicContact CD1-CG2 4.45Å; Y104-V120 HydrophobicContact CE1-CG1 4.04Å; Y104-V120 HydrophobicContact CG-CG1 4.4Å; Y104-H263 HydrophobicContact CE2-CB 3.91Å; Y104-L267 HydrophobicContact CD2-CD1 4.21Å; Y104-L267 HydrophobicContact CG-CD1 4.47Å; Y104-L406 HydrophobicContact CE1-CD2 3.92Å; Y104-L406 PolarHBondContact OH-O 2.94Å; Y104-F410 HydrophobicContact CE1-CB 4.11Å; Y104-F410 HydrophobicContact CE1-CD2 4.12Å; Y104-P411 VanDerWaalsContact OH-CD 3.31Å; Y104-P411 WeakPolarHBondContact OH-CD 3.23Å; Y104-P411 VanDerWaalsContact OH-CG 3.25Å; Y104-P411 WeakPolarHBondContact OH-CG 3.42Å; Y104-F414 HydrophobicContact CD1-CE2 4.01Å; Y104-F414 AromaticContact CE1-CE2 3.62Å; Y104-F414 HydrophobicContact CE1-CE2 3.62Å; Y104-F414 HydrophobicContact CE1-CZ 4.28Å
105	E	92	Very high	92.8	Very high	24 Å²	24	58 Å²	58	11%	0.112	30%	0.302	C	S	.	.	H	α-helix	trans	-64.5	-41	175.9	-59.6	93.3	142.8	0	0	112.2	S103 L107 G108 E109 K117 V120 I124	S103-E105 PolarHBondContact OG-OE2 3.26Å; E105-L107 VanDerWaalsContact C-N 3.34Å; E105-G108 PolarHBondContact O-N 3.46Å; E105-E109 PolarHBondContact O-N 3.44Å; E105-K117 HydrophobicContact CB-CG 4.19Å; E105-V120 HydrophobicContact CB-CG1 4.45Å; E105-V120 HydrophobicContact CG-CG1 4.1Å; E105-I124 HydrophobicContact CG-CD1 4.16Å
106	E	91.8	Very high	92.7	Very high	88 Å²	88	58 Å²	58	41%	0.411	30%	0.303	S	S	.	.	H	α-helix	trans	-70.4	-33.4	178.5	-68.5	175.7	-173.4	0	0	111.8	I101 S103 G108 E109 K110	I101-E106 HydrophobicContact CG2-CB 3.42Å; I101-E106 VanDerWaalsContact CG2-CB 3.42Å; S103-E106 PolarHBondContact O-N 2.92Å; E106-G108 VanDerWaalsContact C-N 3.32Å; E106-E109 WeakPolarHBondContact O-CB 3.2Å; E106-E109 PolarHBondContact O-N 3.25Å; E106-K110 PolarHBondContact O-N 2.93Å
107	L	94.1	Very high	92.7	Very high	0 Å²	0	60.7 Å²	60.7	0%	0	31%	0.314	C	S	.	.	H	α-helix	trans	-66.3	-38.6	172.8	-162.9	68	0	0	0	111.2	L92 L95 I101 S103 Y104 E105 E109 K110 A111 F414 I418	L92-L107 HydrophobicContact CD1-CD2 3.35Å; L92-L107 HydrophobicContact CG-CD2 4.43Å; L95-L107 HydrophobicContact CB-CD1 3.98Å; L95-L107 HydrophobicContact CB-CD2 4.09Å; L95-L107 HydrophobicContact CD1-CD1 4.46Å; L95-L107 HydrophobicContact CD1-CD2 3.87Å; L95-L107 HydrophobicContact CD1-CG 4.5Å; I101-L107 HydrophobicContact CG2-CB 4.47Å; S103-L107 PolarHBondContact O-N 3.18Å; Y104-L107 PolarHBondContact O-N 2.92Å; E105-L107 VanDerWaalsContact C-N 3.34Å; L107-E109 VanDerWaalsContact C-N 3.34Å; L107-K110 PolarHBondContact O-N 3.35Å; L107-A111 WeakPolarHBondContact O-CB 3.5Å; L107-A111 PolarHBondContact O-N 3.43Å; L107-F414 HydrophobicContact CB-CD2 4.29Å; L107-F414 HydrophobicContact CB-CE2 4.46Å; L107-F414 HydrophobicContact CD2-CB 4.19Å; L107-F414 HydrophobicContact CD2-CD2 3.63Å; L107-F414 HydrophobicContact CD2-CE2 4.41Å; L107-F414 HydrophobicContact CD2-CG 4.26Å; L107-F414 HydrophobicContact CG-CB 4.27Å; L107-F414 HydrophobicContact CG-CD2 3.87Å; L107-F414 HydrophobicContact CG-CG 4.22Å; L107-I418 HydrophobicContact CD1-CD1 3.42Å; L107-I418 VanDerWaalsContact CD1-CD1 3.42Å; L107-I418 HydrophobicContact CG-CD1 3.86Å
108	G	94.8	Very high	92.7	Very high	0 Å²	0	60.6 Å²	60.6	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-60.6	-40.5	168.8	0	0	0	0	0	113.1	Y104 E105 E106 A111 L112	Y104-G108 PolarHBondContact O-N 3.16Å; Y104-G108 VanDerWaalsContact O-N 3.09Å; E105-G108 PolarHBondContact O-N 3.46Å; E106-G108 VanDerWaalsContact C-N 3.32Å; G108-A111 PolarHBondContact O-N 3.43Å; G108-L112 PolarHBondContact O-N 3.43Å
109	E	94.6	Very high	92.8	Very high	67 Å²	67	60.7 Å²	60.7	31%	0.313	32%	0.315	S	S	.	.	H	α-helix	trans	-63.2	-42	174.1	-168	165.9	-162.7	0	0	112	E105 E106 L107 K113 K117	E105-E109 PolarHBondContact O-N 3.44Å; E106-E109 WeakPolarHBondContact O-CB 3.2Å; E106-E109 PolarHBondContact O-N 3.25Å; L107-E109 VanDerWaalsContact C-N 3.34Å; E109-K113 WeakPolarHBondContact CA-O 3.35Å; E109-K113 WeakPolarHBondContact O-CA 3.42Å; E109-K113 PolarHBondContact O-N 2.88Å; E109-K117 HydrophobicContact CB-CB 3.93Å; E109-K117 HydrophobicContact CB-CD 4.45Å; E109-K117 HydrophobicContact CB-CG 4.3Å; E109-K117 HydrophobicContact CG-CB 4.37Å; E109-K117 WeakPolarHBondContact OE2-CD 3.13Å; E109-K117 WeakPolarHBondContact OE2-CE 3.27Å; E109-K117 IonicContact OE2-NZ 2.74Å; E109-K117 PolarHBondContact OE2-NZ 3.49Å
110	K	94.9	Very high	92.8	Very high	139 Å²	139	58.7 Å²	58.7	60%	0.604	30%	0.303	S	S	*	.	H	α-helix	trans	-66.4	-41.5	178.9	-172	67.7	176.3	-171.9	0	112	I101 E106 L107 I418	I101-K110 HydrophobicContact CD1-CB 3.88Å; I101-K110 HydrophobicContact CD1-CD 4.29Å; I101-K110 HydrophobicContact CD1-CG 4.03Å; E106-K110 PolarHBondContact O-N 2.93Å; L107-K110 PolarHBondContact O-N 3.35Å; K110-I418 HydrophobicContact CB-CD1 4Å; K110-I418 HydrophobicContact CG-CD1 3.98Å; K110-I418 HydrophobicContact CG-CG1 4.23Å
111	A	95.3	Very high	92.9	Very high	16 Å²	16	56.1 Å²	56.1	13%	0.132	28%	0.277	C	S	.	.	H	α-helix	trans	-76.5	-42.3	-178	0	0	0	0	0	113.5	L107 G108 F414 K417 I418	L107-A111 WeakPolarHBondContact O-CB 3.5Å; L107-A111 PolarHBondContact O-N 3.43Å; G108-A111 PolarHBondContact O-N 3.43Å; A111-F414 HydrophobicContact CB-CB 4.48Å; A111-F414 HydrophobicContact CB-CD1 3.51Å; A111-F414 HydrophobicContact CB-CE1 4.17Å; A111-F414 HydrophobicContact CB-CG 4.29Å; A111-K417 HydrophobicContact CB-CB 4.09Å; A111-I418 HydrophobicContact CB-CD1 3.88Å; A111-I418 HydrophobicContact CB-CG1 3.99Å
112	L	95	Very high	93.1	Very high	58 Å²	58	58.6 Å²	58.6	30%	0.304	29%	0.29	S	S	.	.	H	α-helix	trans	-128.1	14	-166.9	-61.9	175.9	0	0	0	113.2	G108 P115 I413	G108-L112 PolarHBondContact O-N 3.43Å; L112-P115 WeakPolarHBondContact O-CD 3.43Å; L112-P115 WeakPolarHBondContact O-CG 3.44Å; L112-I413 HydrophobicContact CD1-CG2 4.22Å; L112-I413 HydrophobicContact CD2-CG2 4.18Å; L112-I413 HydrophobicContact CG-CG2 4.38Å
113	K	94.3	Very high	93.5	Very high	164 Å²	164	55.7 Å²	55.7	71%	0.713	28%	0.275	S	S	*	.	H	α-helix	trans	60.8	-163.9	-175.7	-53.6	-179.8	178.4	179.4	0	111.6	E109 G116 K117	E109-K113 WeakPolarHBondContact CA-O 3.35Å; E109-K113 WeakPolarHBondContact O-CA 3.42Å; E109-K113 PolarHBondContact O-N 2.88Å; K113-G116 WeakPolarHBondContact O-CA 3.5Å; K113-G116 PolarHBondContact O-N 3.09Å; K113-K117 PolarHBondContact O-N 2.97Å
114	K	91.8	Very high	93.7	Very high	155 Å²	155	54.9 Å²	54.9	67%	0.674	27%	0.269	S	S	*	.	H	α-helix	trans	-46	-43.9	178.7	-67.1	-171.9	177.2	-176.6	0	115.8	G116 K117 I118	K114-G116 VanDerWaalsContact C-N 3.27Å; K114-G116 PolarHBondContact O-N 3.05Å; K114-K117 WeakPolarHBondContact O-CB 3.31Å; K114-K117 PolarHBondContact O-N 3.19Å; K114-I118 PolarHBondContact O-N 3.42Å
115	P	93.4	Very high	93.9	Very high	91 Å²	91	55.2 Å²	55.2	59%	0.591	27%	0.272	S	S	*	.	H	α-helix	trans	-65	-32.6	178.9	25	-33.2	0	0	0	112.2	L112 I118 L119	L112-P115 WeakPolarHBondContact O-CD 3.43Å; L112-P115 WeakPolarHBondContact O-CG 3.44Å; P115-I118 PolarHBondContact O-N 2.87Å; P115-L119 VanDerWaalsContact O-CB 3.32Å; P115-L119 WeakPolarHBondContact O-CB 3.36Å; P115-L119 PolarHBondContact O-N 3.4Å
116	G	93.6	Very high	94	Very high	2 Å²	2	57.3 Å²	57.3	2%	0.021	28%	0.283	C	S	.	.	H	α-helix	trans	-58.6	-47.7	172.1	0	0	0	0	0	113.2	K113 K114 I118 L119 V120	K113-G116 WeakPolarHBondContact O-CA 3.5Å; K113-G116 PolarHBondContact O-N 3.09Å; K114-G116 VanDerWaalsContact C-N 3.27Å; K114-G116 PolarHBondContact O-N 3.05Å; G116-I118 VanDerWaalsContact C-N 3.33Å; G116-I118 PolarHBondContact O-N 3.27Å; G116-L119 PolarHBondContact O-N 2.85Å; G116-V120 WeakPolarHBondContact O-CB 3.42Å; G116-V120 VanDerWaalsContact O-CG2 3.27Å; G116-V120 WeakPolarHBondContact O-CG2 3.35Å; G116-V120 PolarHBondContact O-N 3.29Å
117	K	92.2	Very high	94.2	Very high	58 Å²	58	53.4 Å²	53.4	25%	0.252	27%	0.265	S	S	.	.	H	α-helix	trans	-55.5	-48.3	176.9	-166.6	-175	-164.2	144.3	0	112	E105 E109 K113 K114 G121	E105-K117 HydrophobicContact CB-CG 4.19Å; E109-K117 HydrophobicContact CB-CB 3.93Å; E109-K117 HydrophobicContact CB-CD 4.45Å; E109-K117 HydrophobicContact CB-CG 4.3Å; E109-K117 HydrophobicContact CG-CB 4.37Å; E109-K117 WeakPolarHBondContact OE2-CD 3.13Å; E109-K117 WeakPolarHBondContact OE2-CE 3.27Å; E109-K117 IonicContact OE2-NZ 2.74Å; E109-K117 PolarHBondContact OE2-NZ 3.49Å; K113-K117 PolarHBondContact O-N 2.97Å; K114-K117 WeakPolarHBondContact O-CB 3.31Å; K114-K117 PolarHBondContact O-N 3.19Å; K117-G121 PolarHBondContact O-N 2.87Å
118	I	92.5	Very high	94.2	Very high	100 Å²	100	53.7 Å²	53.7	51%	0.513	27%	0.266	S	S	.	.	H	α-helix	trans	-67.1	-43.8	-177.8	-65.9	168.8	0	0	0	110.5	K114 P115 G116 V120 G121 L122 M358	K114-I118 PolarHBondContact O-N 3.42Å; P115-I118 PolarHBondContact O-N 2.87Å; G116-I118 VanDerWaalsContact C-N 3.33Å; G116-I118 PolarHBondContact O-N 3.27Å; I118-V120 PolarHBondContact O-N 3.41Å; I118-G121 PolarHBondContact O-N 3.35Å; I118-L122 WeakPolarHBondContact O-CB 3.28Å; I118-L122 PolarHBondContact O-N 3.31Å; I118-M358 HydrophobicContact CG2-CE 4.05Å
119	L	94.7	Very high	94.3	Very high	90 Å²	90	55 Å²	55	47%	0.471	27%	0.273	S	S	.	.	H	α-helix	trans	-62.4	-44.8	-179.6	-176.5	65.9	0	0	0	111.7	P115 G116 A123 F410	P115-L119 VanDerWaalsContact O-CB 3.32Å; P115-L119 WeakPolarHBondContact O-CB 3.36Å; P115-L119 PolarHBondContact O-N 3.4Å; G116-L119 PolarHBondContact O-N 2.85Å; L119-A123 WeakPolarHBondContact O-CB 2.93Å; L119-A123 PolarHBondContact O-N 2.98Å; L119-F410 HydrophobicContact CD2-CE1 3.8Å; L119-F410 HydrophobicContact CD2-CZ 4.01Å; L119-F410 HydrophobicContact CG-CE1 4.19Å; L119-F410 HydrophobicContact CG-CZ 3.88Å
120	V	94	Very high	94.3	Very high	1 Å²	1	52 Å²	52	1%	0.006	26%	0.259	C	S	.	.	H	α-helix	trans	-62.6	-50.3	174.8	169.9	0	0	0	0	111.2	Y104 E105 G116 I118 L122 A123 I124 F410 F414	Y104-V120 HydrophobicContact CD1-CG1 3.41Å; Y104-V120 VanDerWaalsContact CD1-CG1 3.41Å; Y104-V120 HydrophobicContact CD1-CG2 4.45Å; Y104-V120 HydrophobicContact CE1-CG1 4.04Å; Y104-V120 HydrophobicContact CG-CG1 4.4Å; E105-V120 HydrophobicContact CB-CG1 4.45Å; E105-V120 HydrophobicContact CG-CG1 4.1Å; G116-V120 WeakPolarHBondContact O-CB 3.42Å; G116-V120 VanDerWaalsContact O-CG2 3.27Å; G116-V120 WeakPolarHBondContact O-CG2 3.35Å; G116-V120 PolarHBondContact O-N 3.29Å; I118-V120 PolarHBondContact O-N 3.41Å; V120-L122 VanDerWaalsContact C-N 3.28Å; V120-L122 PolarHBondContact O-N 2.97Å; V120-A123 WeakPolarHBondContact O-CB 3.29Å; V120-A123 PolarHBondContact O-N 3.35Å; V120-A123 VanDerWaalsContact O-N 3.11Å; V120-I124 HydrophobicContact CG1-CD1 3.77Å; V120-I124 HydrophobicContact CG1-CG1 4.33Å; V120-I124 WeakPolarHBondContact O-CG1 3.36Å; V120-I124 PolarHBondContact O-N 3.24Å; V120-F410 HydrophobicContact CG2-CD2 4.18Å; V120-F410 HydrophobicContact CG2-CE2 4.22Å; V120-F414 HydrophobicContact CG2-CE1 4.45Å; V120-F414 HydrophobicContact CG2-CE2 4.38Å; V120-F414 HydrophobicContact CG2-CZ 3.56Å
121	G	93.1	Very high	94.3	Very high	0 Å²	0	45.8 Å²	45.8	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-57.2	-44.3	179.9	0	0	0	0	0	111.6	K117 I118 A123 I124 V125	K117-G121 PolarHBondContact O-N 2.87Å; I118-G121 PolarHBondContact O-N 3.35Å; G121-A123 PolarHBondContact O-N 2.91Å; G121-I124 PolarHBondContact O-N 3.33Å; G121-V125 VanDerWaalsContact O-CG2 3.31Å; G121-V125 WeakPolarHBondContact O-CG2 3.32Å; G121-V125 PolarHBondContact O-N 3.48Å
122	L	94.8	Very high	94.3	Very high	82 Å²	82	45 Å²	45	43%	0.429	23%	0.228	S	C	.	.	H	α-helix	trans	-61.8	-44.1	175.7	-176.4	62.1	0	0	0	111.7	I118 V120 I124 V125 I126 M358	I118-L122 WeakPolarHBondContact O-CB 3.28Å; I118-L122 PolarHBondContact O-N 3.31Å; V120-L122 VanDerWaalsContact C-N 3.28Å; V120-L122 PolarHBondContact O-N 2.97Å; L122-I124 VanDerWaalsContact C-N 3.35Å; L122-I124 PolarHBondContact O-N 3.33Å; L122-V125 PolarHBondContact O-N 3Å; L122-I126 HydrophobicContact CD1-CD1 3.86Å; L122-I126 HydrophobicContact CD1-CG1 4.1Å; L122-I126 HydrophobicContact CD2-CD1 4.37Å; L122-I126 HydrophobicContact CG-CD1 3.75Å; L122-I126 HydrophobicContact CG-CG1 4.35Å; L122-I126 WeakPolarHBondContact O-CG1 3.42Å; L122-I126 PolarHBondContact O-N 3.4Å; L122-M358 HydrophobicContact CB-CE 4.05Å
123	A	95.5	Very high	94.3	Very high	5 Å²	5	42.4 Å²	42.4	4%	0.041	22%	0.215	C	C	.	.	H	α-helix	trans	-61.9	-42.1	178	0	0	0	0	0	112.2	L119 V120 G121 Q127 M402 L406 F410	L119-A123 WeakPolarHBondContact O-CB 2.93Å; L119-A123 PolarHBondContact O-N 2.98Å; V120-A123 WeakPolarHBondContact O-CB 3.29Å; V120-A123 PolarHBondContact O-N 3.35Å; V120-A123 VanDerWaalsContact O-N 3.11Å; G121-A123 PolarHBondContact O-N 2.91Å; A123-Q127 WeakPolarHBondContact O-CB 3.44Å; A123-Q127 PolarHBondContact O-N 2.97Å; A123-M402 HydrophobicContact CB-SD 4.01Å; A123-L406 HydrophobicContact CB-CD1 4.39Å; A123-L406 HydrophobicContact CB-CD2 4.18Å; A123-L406 HydrophobicContact CB-CG 4.18Å; A123-F410 HydrophobicContact CB-CE2 3.76Å; A123-F410 HydrophobicContact CB-CZ 4.32Å
124	I	94.1	Very high	94.4	Very high	6 Å²	6	34.6 Å²	34.6	3%	0.031	18%	0.181	C	C	.	.	H	α-helix	trans	-61.7	-44.5	175.2	-66.5	172.8	0	0	0	110.6	E105 V120 G121 L122 N128 T264 A354 L406	E105-I124 HydrophobicContact CG-CD1 4.16Å; V120-I124 HydrophobicContact CG1-CD1 3.77Å; V120-I124 HydrophobicContact CG1-CG1 4.33Å; V120-I124 WeakPolarHBondContact O-CG1 3.36Å; V120-I124 PolarHBondContact O-N 3.24Å; G121-I124 PolarHBondContact O-N 3.33Å; L122-I124 VanDerWaalsContact C-N 3.35Å; L122-I124 PolarHBondContact O-N 3.33Å; I124-N128 WeakPolarHBondContact O-CB 3.49Å; I124-N128 VanDerWaalsContact O-CG 3.23Å; I124-N128 PolarHBondContact O-N 2.85Å; I124-N128 PolarHBondContact O-ND2 3.4Å; I124-T264 HydrophobicContact CB-CG2 4.46Å; I124-T264 HydrophobicContact CG1-CG2 3.99Å; I124-T264 HydrophobicContact CG2-CG2 4.16Å; I124-A354 HydrophobicContact CG2-CB 4.37Å; I124-L406 HydrophobicContact CG1-CD2 3.89Å
125	V	94.7	Very high	94.5	Very high	14 Å²	14	27.5 Å²	27.5	9%	0.085	15%	0.15	C	C	.	.	H	α-helix	trans	-64.1	-51.1	179.5	171.4	0	0	0	0	111.3	G121 L122 Q127 N128 I129 A354 V355	G121-V125 VanDerWaalsContact O-CG2 3.31Å; G121-V125 WeakPolarHBondContact O-CG2 3.32Å; G121-V125 PolarHBondContact O-N 3.48Å; L122-V125 PolarHBondContact O-N 3Å; V125-Q127 VanDerWaalsContact C-N 3.31Å; V125-Q127 PolarHBondContact O-N 3.34Å; V125-N128 PolarHBondContact O-N 2.93Å; V125-I129 HydrophobicContact CG1-CD1 3.76Å; V125-I129 HydrophobicContact CG1-CG1 4.44Å; V125-I129 WeakPolarHBondContact O-CB 3.41Å; V125-I129 VanDerWaalsContact O-CG1 3.29Å; V125-I129 WeakPolarHBondContact O-CG1 3.25Å; V125-I129 PolarHBondContact O-N 3.4Å; V125-A354 HydrophobicContact CG2-CB 3.64Å; V125-V355 HydrophobicContact CB-CG2 4.48Å; V125-V355 HydrophobicContact CG1-CG2 3.9Å; V125-V355 HydrophobicContact CG2-CG2 3.66Å
126	I	95.7	Very high	94.6	Very high	67 Å²	67	23.2 Å²	23.2	34%	0.344	12%	0.122	S	C	.	.	H	α-helix	trans	-63	-41.3	-179.7	-62.9	170.8	0	0	0	110.3	L122 I129 G130 M402	L122-I126 HydrophobicContact CD1-CD1 3.86Å; L122-I126 HydrophobicContact CD1-CG1 4.1Å; L122-I126 HydrophobicContact CD2-CD1 4.37Å; L122-I126 HydrophobicContact CG-CD1 3.75Å; L122-I126 HydrophobicContact CG-CG1 4.35Å; L122-I126 WeakPolarHBondContact O-CG1 3.42Å; L122-I126 PolarHBondContact O-N 3.4Å; I126-I129 PolarHBondContact O-N 3.33Å; I126-G130 PolarHBondContact O-N 2.84Å; I126-M402 HydrophobicContact CB-CG 3.76Å; I126-M402 HydrophobicContact CB-SD 3.82Å; I126-M402 HydrophobicContact CD1-SD 3.93Å; I126-M402 HydrophobicContact CG1-SD 4.45Å; I126-M402 HydrophobicContact CG2-CG 3.47Å; I126-M402 VanDerWaalsContact CG2-CG 3.47Å; I126-M402 HydrophobicContact CG2-SD 3.95Å
127	Q	95.1	Very high	94.7	Very high	7 Å²	7	23.8 Å²	23.8	3%	0.033	12%	0.124	C	C	.	.	H	α-helix	trans	-59	-49.5	175.5	177	64.4	42.5	0	0	112.2	A123 V125 I129 G130 A131 F258 L261 M402 S403 L406	A123-Q127 WeakPolarHBondContact O-CB 3.44Å; A123-Q127 PolarHBondContact O-N 2.97Å; V125-Q127 VanDerWaalsContact C-N 3.31Å; V125-Q127 PolarHBondContact O-N 3.34Å; Q127-I129 VanDerWaalsContact C-N 3.34Å; Q127-G130 WeakPolarHBondContact O-CA 3.48Å; Q127-G130 PolarHBondContact O-N 2.99Å; Q127-A131 PolarHBondContact O-N 3.28Å; Q127-F258 VanDerWaalsContact NE2-CD2 3.33Å; Q127-L261 HydrophobicContact CB-CD2 4.48Å; Q127-L261 HydrophobicContact CG-CD2 3.26Å; Q127-M402 HydrophobicContact CB-CB 4.03Å; Q127-S403 PolarHBondContact NE2-OG 2.91Å; Q127-S403 VanDerWaalsContact OE1-N 3.16Å; Q127-S403 PolarHBondContact OE1-OG 2.97Å; Q127-L406 HydrophobicContact CB-CD1 3.82Å; Q127-L406 HydrophobicContact CG-CD1 4.03Å
128	N	94.5	Very high	94.8	Very high	6 Å²	6	21 Å²	21	3%	0.032	11%	0.112	C	C	.	.	H	α-helix	trans	-67.6	-36.3	-178.5	-73.9	-20.9	0	0	0	111.4	I124 V125 G130 A131 M132 I347 A351	I124-N128 WeakPolarHBondContact O-CB 3.49Å; I124-N128 VanDerWaalsContact O-CG 3.23Å; I124-N128 PolarHBondContact O-N 2.85Å; I124-N128 PolarHBondContact O-ND2 3.4Å; V125-N128 PolarHBondContact O-N 2.93Å; N128-G130 VanDerWaalsContact C-N 3.33Å; N128-A131 PolarHBondContact O-N 2.84Å; N128-M132 HydrophobicContact CB-CE 4.38Å; N128-M132 WeakPolarHBondContact O-CB 3.28Å; N128-M132 WeakPolarHBondContact O-CE 3.25Å; N128-M132 VanDerWaalsContact O-CG 3.32Å; N128-M132 WeakPolarHBondContact O-CG 3.43Å; N128-M132 PolarHBondContact O-N 2.98Å; N128-I347 HydrophobicContact CB-CG2 3.64Å; N128-A351 HydrophobicContact CB-CB 3.7Å; N128-A351 PolarHBondContact ND2-N 3.33Å
129	I	95.7	Very high	94.9	Very high	27 Å²	27	16.3 Å²	16.3	14%	0.138	9%	0.088	C	C	.	.	H	α-helix	trans	-59.7	-46	170.4	-72.4	170.5	0	0	0	110.1	V125 I126 Q127 M132 S133 I377 V380 V381 L384	V125-I129 HydrophobicContact CG1-CD1 3.76Å; V125-I129 HydrophobicContact CG1-CG1 4.44Å; V125-I129 WeakPolarHBondContact O-CB 3.41Å; V125-I129 VanDerWaalsContact O-CG1 3.29Å; V125-I129 WeakPolarHBondContact O-CG1 3.25Å; V125-I129 PolarHBondContact O-N 3.4Å; I126-I129 PolarHBondContact O-N 3.33Å; Q127-I129 VanDerWaalsContact C-N 3.34Å; I129-M132 PolarHBondContact O-N 2.89Å; I129-S133 VanDerWaalsContact O-CB 3.31Å; I129-S133 WeakPolarHBondContact O-CB 3.44Å; I129-S133 PolarHBondContact O-N 3.38Å; I129-S133 PolarHBondContact O-OG 2.93Å; I129-I377 HydrophobicContact CG1-CG2 4.45Å; I129-V380 HydrophobicContact CD1-CG1 4.45Å; I129-V380 HydrophobicContact CG2-CG1 4.22Å; I129-V381 HydrophobicContact CB-CG2 4.32Å; I129-V381 HydrophobicContact CG1-CG2 4.24Å; I129-V381 HydrophobicContact CG2-CG2 4.05Å; I129-L384 HydrophobicContact CG2-CD1 3.49Å; I129-L384 VanDerWaalsContact CG2-CD1 3.49Å
130	G	95.4	Very high	94.9	Very high	3 Å²	3	13.5 Å²	13.5	3%	0.031	7%	0.072	C	C	.	.	H	α-helix	trans	-56.7	-50.1	174.9	0	0	0	0	0	112.8	I126 Q127 N128 S133 S134 V394	I126-G130 PolarHBondContact O-N 2.84Å; Q127-G130 WeakPolarHBondContact O-CA 3.48Å; Q127-G130 PolarHBondContact O-N 2.99Å; N128-G130 VanDerWaalsContact C-N 3.33Å; G130-S133 PolarHBondContact O-N 3.23Å; G130-S133 PolarHBondContact O-OG 3.37Å; G130-S134 PolarHBondContact O-N 2.99Å; G130-S134 PolarHBondContact O-OG 3.31Å; G130-V394 WeakPolarHBondContact O-CG1 3.4Å
131	A	94.7	Very high	94.8	Very high	9 Å²	9	14.8 Å²	14.8	7%	0.074	8%	0.081	C	C	.	.	H	α-helix	trans	-62.9	-41.7	177.6	0	0	0	0	0	113.8	Q127 N128 S133 S134 Y135 F258 I347	Q127-A131 PolarHBondContact O-N 3.28Å; N128-A131 PolarHBondContact O-N 2.84Å; A131-S133 VanDerWaalsContact C-N 3.32Å; A131-S134 PolarHBondContact O-OG 3.02Å; A131-Y135 WeakPolarHBondContact O-CD2 3.43Å; A131-Y135 PolarHBondContact O-N 3.26Å; A131-F258 HydrophobicContact CB-CE2 4.44Å; A131-F258 HydrophobicContact CB-CZ 4.09Å; A131-I347 HydrophobicContact CB-CD1 3.84Å; A131-I347 HydrophobicContact CB-CG2 4.28Å
132	M	95.6	Very high	94.8	Very high	0 Å²	0	14.9 Å²	14.9	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-68.3	-33.8	174	-67.5	-177.2	-76.3	0	0	111.8	N128 I129 Y135 L136 V344 I347 H348 A351 I377 V381	N128-M132 HydrophobicContact CB-CE 4.38Å; N128-M132 WeakPolarHBondContact O-CB 3.28Å; N128-M132 WeakPolarHBondContact O-CE 3.25Å; N128-M132 VanDerWaalsContact O-CG 3.32Å; N128-M132 WeakPolarHBondContact O-CG 3.43Å; N128-M132 PolarHBondContact O-N 2.98Å; I129-M132 PolarHBondContact O-N 2.89Å; M132-Y135 WeakPolarHBondContact O-CB 3.46Å; M132-Y135 PolarHBondContact O-N 3.27Å; M132-L136 WeakPolarHBondContact O-CG 3.46Å; M132-L136 PolarHBondContact O-N 3.39Å; M132-V344 HydrophobicContact CG-CG1 4.27Å; M132-V344 HydrophobicContact SD-CG1 4.33Å; M132-I347 HydrophobicContact CG-CB 3.96Å; M132-I347 HydrophobicContact CG-CG2 3.73Å; M132-I347 HydrophobicContact SD-CG2 4.38Å; M132-H348 VanDerWaalsContact SD-CA 3.52Å; M132-H348 HydrophobicContact SD-CB 3.61Å; M132-A351 HydrophobicContact CE-CB 4.09Å; M132-I377 HydrophobicContact CE-CG2 3.74Å; M132-V381 HydrophobicContact CB-CB 4.44Å; M132-V381 HydrophobicContact CB-CG1 3.57Å; M132-V381 HydrophobicContact CB-CG2 3.92Å; M132-V381 HydrophobicContact CE-CG2 3.92Å; M132-V381 HydrophobicContact SD-CG2 4.49Å
133	S	95.8	Very high	94.6	Very high	4 Å²	4	12.3 Å²	12.3	3%	0.028	7%	0.067	C	C	.	.	H	α-helix	trans	-69.8	-36.8	179.7	73.1	0	0	0	0	112.3	I129 G130 A131 Y135 L136 F137 V394	I129-S133 VanDerWaalsContact O-CB 3.31Å; I129-S133 WeakPolarHBondContact O-CB 3.44Å; I129-S133 PolarHBondContact O-N 3.38Å; I129-S133 PolarHBondContact O-OG 2.93Å; G130-S133 PolarHBondContact O-N 3.23Å; G130-S133 PolarHBondContact O-OG 3.37Å; A131-S133 VanDerWaalsContact C-N 3.32Å; S133-Y135 VanDerWaalsContact C-N 3.32Å; S133-L136 PolarHBondContact O-N 3.01Å; S133-F137 WeakPolarHBondContact O-CB 3.39Å; S133-F137 PolarHBondContact O-N 3.49Å; S133-V394 WeakPolarHBondContact OG-CG1 3.31Å
134	S	95.5	Very high	94.4	Very high	0 Å²	0	12.8 Å²	12.8	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-66.7	-35.7	174	54.9	0	0	0	0	112	S57 G130 A131 F137 I138 F395	S57-S134 WeakPolarHBondContact OG-CB 3.4Å; S57-S134 PolarHBondContact OG-OG 2.88Å; G130-S134 PolarHBondContact O-N 2.99Å; G130-S134 PolarHBondContact O-OG 3.31Å; A131-S134 PolarHBondContact O-OG 3.02Å; S134-F137 WeakPolarHBondContact O-CB 3.27Å; S134-F137 PolarHBondContact O-N 3.24Å; S134-I138 WeakPolarHBondContact O-CG1 3.47Å; S134-I138 PolarHBondContact O-N 3.49Å; S134-I138 VanDerWaalsContact O-N 3.1Å; S134-F395 VanDerWaalsContact CB-CE1 3.47Å
135	Y	94.9	Very high	94	Very high	6 Å²	6	13.7 Å²	13.7	2%	0.024	8%	0.078	C	C	.	.	H	α-helix	trans	-63.6	-47.9	170.7	-76.7	-34.1	0	0	0	113.6	G56 A131 M132 S133 F137 I138 L139 V340 T343 V344 I347	G56-Y135 WeakPolarHBondContact CA-OH 3.02Å; A131-Y135 WeakPolarHBondContact O-CD2 3.43Å; A131-Y135 PolarHBondContact O-N 3.26Å; M132-Y135 WeakPolarHBondContact O-CB 3.46Å; M132-Y135 PolarHBondContact O-N 3.27Å; S133-Y135 VanDerWaalsContact C-N 3.32Å; Y135-F137 PolarHBondContact O-N 2.97Å; Y135-I138 HydrophobicContact CD1-CD1 4.38Å; Y135-I138 PolarHBondContact O-N 3.49Å; Y135-L139 PolarHBondContact O-N 3.24Å; Y135-V340 VanDerWaalsContact CB-CG1 3.4Å; Y135-V340 HydrophobicContact CD1-CB 4.15Å; Y135-V340 HydrophobicContact CD1-CG1 3.64Å; Y135-V340 HydrophobicContact CD1-CG2 3.62Å; Y135-V340 HydrophobicContact CE1-CG2 4.08Å; Y135-V340 HydrophobicContact CG-CG1 3.69Å; Y135-V340 HydrophobicContact CG-CG2 4.5Å; Y135-T343 HydrophobicContact CE2-CG2 3.65Å; Y135-T343 WeakPolarHBondContact OH-CG2 3.35Å; Y135-V344 HydrophobicContact CD2-CG2 3.73Å; Y135-V344 HydrophobicContact CG-CG2 3.98Å; Y135-I347 HydrophobicContact CD2-CD1 4.41Å; Y135-I347 HydrophobicContact CE2-CD1 3.52Å; Y135-I347 HydrophobicContact CE2-CG1 4.39Å
136	L	95.6	Very high	93.7	Very high	1 Å²	1	13.1 Å²	13.1	1%	0.005	8%	0.075	C	C	.	.	H	α-helix	trans	-64.7	-30.5	175.9	-69.1	-154.5	0	0	0	111.9	M132 S133 L139 K140 L168 I176 V344 V381 L382 A385	M132-L136 WeakPolarHBondContact O-CG 3.46Å; M132-L136 PolarHBondContact O-N 3.39Å; S133-L136 PolarHBondContact O-N 3.01Å; L136-L139 HydrophobicContact CD2-CD1 3.8Å; L136-L139 PolarHBondContact O-N 3.43Å; L136-K140 WeakPolarHBondContact O-CB 3.47Å; L136-K140 PolarHBondContact O-N 3.16Å; L136-L168 HydrophobicContact CB-CD1 3.94Å; L136-L168 HydrophobicContact CB-CD2 4.48Å; L136-L168 HydrophobicContact CD1-CD1 4.39Å; L136-L168 HydrophobicContact CD2-CD1 4.19Å; L136-L168 HydrophobicContact CG-CD1 4.38Å; L136-L168 WeakPolarHBondContact O-CD1 3.43Å; L136-I176 HydrophobicContact CD2-CD1 3.4Å; L136-V344 HydrophobicContact CD2-CG2 4.38Å; L136-V381 HydrophobicContact CD1-CG1 3.62Å; L136-V381 HydrophobicContact CG-CG1 3.88Å; L136-L382 HydrophobicContact CD1-CB 4.34Å; L136-L382 HydrophobicContact CD1-CD1 4.29Å; L136-A385 HydrophobicContact CB-CB 3.43Å; L136-A385 VanDerWaalsContact CB-CB 3.43Å; L136-A385 HydrophobicContact CD1-CB 4.38Å
137	F	95.1	Very high	93.4	Very high	13 Å²	13	12 Å²	12	6%	0.057	7%	0.07	C	C	.	.	H	α-helix	trans	-63	-45.6	171.7	-174.2	-80.6	0	0	0	111.7	S133 S134 Y135 L139 K140 S141 V388 P389 I391	S133-F137 WeakPolarHBondContact O-CB 3.39Å; S133-F137 PolarHBondContact O-N 3.49Å; S134-F137 WeakPolarHBondContact O-CB 3.27Å; S134-F137 PolarHBondContact O-N 3.24Å; Y135-F137 PolarHBondContact O-N 2.97Å; F137-L139 VanDerWaalsContact C-N 3.29Å; F137-L139 PolarHBondContact O-N 2.92Å; F137-K140 WeakPolarHBondContact O-CA 3.32Å; F137-K140 VanDerWaalsContact O-CB 3.29Å; F137-K140 WeakPolarHBondContact O-CB 3.35Å; F137-K140 PolarHBondContact O-N 3.42Å; F137-K140 VanDerWaalsContact O-N 3.08Å; F137-S141 PolarHBondContact O-N 3.43Å; F137-S141 PolarHBondContact O-OG 3.23Å; F137-V388 WeakPolarHBondContact CE2-O 3.23Å; F137-P389 WeakPolarHBondContact CE2-O 3.4Å; F137-P389 WeakPolarHBondContact CZ-O 3.35Å; F137-I391 HydrophobicContact CD1-CB 3.74Å; F137-I391 HydrophobicContact CD1-CD1 4.15Å; F137-I391 HydrophobicContact CD1-CG1 4.24Å; F137-I391 HydrophobicContact CE1-CB 3.89Å; F137-I391 HydrophobicContact CE1-CG2 4.38Å; F137-I391 HydrophobicContact CG-CB 4.2Å; F137-I391 HydrophobicContact CZ-CB 4.46Å
138	I	94	Very high	92.9	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-59.8	-41.5	175.4	-64.7	159	0	0	0	110.6	S57 L60 S134 Y135 K140 S141 E142 I336 V340 I391	S57-I138 VanDerWaalsContact CB-CD1 3.42Å; L60-I138 HydrophobicContact CD1-CD1 3.55Å; L60-I138 HydrophobicContact CD1-CG1 3.86Å; L60-I138 HydrophobicContact CD1-CG2 4.33Å; S134-I138 WeakPolarHBondContact O-CG1 3.47Å; S134-I138 PolarHBondContact O-N 3.49Å; S134-I138 VanDerWaalsContact O-N 3.1Å; Y135-I138 HydrophobicContact CD1-CD1 4.38Å; Y135-I138 PolarHBondContact O-N 3.49Å; I138-K140 VanDerWaalsContact C-N 3.34Å; I138-K140 PolarHBondContact O-N 3.18Å; I138-S141 PolarHBondContact O-N 3.45Å; I138-S141 PolarHBondContact O-OG 3.12Å; I138-E142 HydrophobicContact CG2-CG 4.24Å; I138-E142 WeakPolarHBondContact O-CB 3.16Å; I138-E142 PolarHBondContact O-N 3.41Å; I138-I336 HydrophobicContact CG2-CG2 4.17Å; I138-V340 HydrophobicContact CD1-CG2 4.41Å; I138-I391 HydrophobicContact CD1-CD1 4.31Å; I138-I391 HydrophobicContact CG1-CD1 3.99Å
139	L	94.5	Very high	92.3	Very high	2 Å²	2	13.8 Å²	13.8	1%	0.01	8%	0.083	C	C	.	.	H	α-helix	trans	-61.1	-43.6	173.8	-67.3	177.7	0	0	0	111.4	Y135 L136 F137 S141 L143 L168 V171 I176 L337 V340 L341	Y135-L139 PolarHBondContact O-N 3.24Å; L136-L139 HydrophobicContact CD2-CD1 3.8Å; L136-L139 PolarHBondContact O-N 3.43Å; F137-L139 VanDerWaalsContact C-N 3.29Å; F137-L139 PolarHBondContact O-N 2.92Å; L139-S141 VanDerWaalsContact C-N 3.33Å; L139-S141 PolarHBondContact O-N 3.11Å; L139-L143 WeakPolarHBondContact O-CB 3.3Å; L139-L143 PolarHBondContact O-N 2.98Å; L139-L168 HydrophobicContact CB-CD1 3.9Å; L139-L168 HydrophobicContact CD1-CD1 4.43Å; L139-V171 HydrophobicContact CD1-CG1 4.49Å; L139-I176 HydrophobicContact CD1-CD1 3.91Å; L139-L337 HydrophobicContact CD2-CB 4.41Å; L139-L337 HydrophobicContact CD2-CD2 3.55Å; L139-V340 HydrophobicContact CD1-CG1 4.47Å; L139-V340 HydrophobicContact CD2-CG1 4.38Å; L139-V340 HydrophobicContact CG-CG1 4.14Å; L139-L341 HydrophobicContact CD1-CD2 3.75Å; L139-L341 HydrophobicContact CD2-CD2 4.09Å; L139-L341 HydrophobicContact CD2-CG 4.07Å
140	K	94.4	Very high	91.8	Very high	31 Å²	31	18.4 Å²	18.4	14%	0.135	11%	0.107	C	C	.	.	H	α-helix	trans	-60.8	-40.7	178.2	-169.9	-176.9	68.7	179.1	0	112.3	L136 F137 I138 P144 G164 L168 A385 V388	L136-K140 WeakPolarHBondContact O-CB 3.47Å; L136-K140 PolarHBondContact O-N 3.16Å; F137-K140 WeakPolarHBondContact O-CA 3.32Å; F137-K140 VanDerWaalsContact O-CB 3.29Å; F137-K140 WeakPolarHBondContact O-CB 3.35Å; F137-K140 PolarHBondContact O-N 3.42Å; F137-K140 VanDerWaalsContact O-N 3.08Å; I138-K140 VanDerWaalsContact C-N 3.34Å; I138-K140 PolarHBondContact O-N 3.18Å; K140-P144 WeakPolarHBondContact O-CD 3.46Å; K140-G164 WeakPolarHBondContact O-CA 3.42Å; K140-L168 HydrophobicContact CB-CD2 4.18Å; K140-L168 HydrophobicContact CG-CD2 4.46Å; K140-A385 WeakPolarHBondContact CD-O 3.39Å; K140-A385 WeakPolarHBondContact CE-O 3.11Å; K140-A385 PolarHBondContact NZ-O 2.65Å; K140-V388 PolarHBondContact NZ-O 3.36Å; K140-V388 VanDerWaalsContact NZ-O 3.16Å
141	S	92.1	Very high	91.1	Very high	28 Å²	28	23 Å²	23	20%	0.196	13%	0.131	C	C	.	.	H	α-helix	trans	-85.9	-41.4	-172.6	61.3	0	0	0	0	112.9	F137 I138 L139 E314	F137-S141 PolarHBondContact O-N 3.43Å; F137-S141 PolarHBondContact O-OG 3.23Å; I138-S141 PolarHBondContact O-N 3.45Å; I138-S141 PolarHBondContact O-OG 3.12Å; L139-S141 VanDerWaalsContact C-N 3.33Å; L139-S141 PolarHBondContact O-N 3.11Å; S141-E314 PolarHBondContact OG-OE2 3.45Å
142	E	92.4	Very high	90	Very high	2 Å²	2	29.2 Å²	29.2	1%	0.009	16%	0.163	C	C	.	.	H	α-helix	trans	-97.1	-26.2	-171	-63.9	-64.1	149.5	0	0	114	I138 A145 A146 E314 L316 L317 R333 L337	I138-E142 HydrophobicContact CG2-CG 4.24Å; I138-E142 WeakPolarHBondContact O-CB 3.16Å; I138-E142 PolarHBondContact O-N 3.41Å; E142-A145 PolarHBondContact O-N 2.91Å; E142-A146 WeakPolarHBondContact O-CB 3.48Å; E142-A146 PolarHBondContact O-N 2.84Å; E142-E314 WeakPolarHBondContact CG-OE1 3.5Å; E142-L316 HydrophobicContact CG-CB 4.3Å; E142-L316 VanDerWaalsContact OE1-CB 3.25Å; E142-L316 WeakPolarHBondContact OE1-CB 3.48Å; E142-L317 WeakPolarHBondContact OE1-CD2 3.42Å; E142-L317 PolarHBondContact OE1-N 3.19Å; E142-R333 IonicContact OE2-CZ 3.04Å; E142-R333 VanDerWaalsContact OE2-CZ 3.23Å; E142-R333 IonicContact OE2-NE 2.68Å; E142-R333 PolarHBondContact OE2-NE 2.88Å; E142-R333 IonicContact OE2-NH2 2.7Å; E142-R333 PolarHBondContact OE2-NH2 2.86Å; E142-L337 HydrophobicContact CB-CD2 4.02Å; E142-L337 HydrophobicContact CB-CG 4.48Å
143	L	92.5	Very high	88.3	Confident	27 Å²	27	30.7 Å²	30.7	14%	0.141	18%	0.175	C	C	.	.	H	α-helix	trans	-63.8	-45.8	-178.1	-176.7	63.4	0	0	0	113.5	L139 A145 A146 I147 L167 V171 L337	L139-L143 WeakPolarHBondContact O-CB 3.3Å; L139-L143 PolarHBondContact O-N 2.98Å; L143-A145 VanDerWaalsContact C-N 3.28Å; L143-A145 PolarHBondContact O-N 3.35Å; L143-A146 PolarHBondContact O-N 3.4Å; L143-I147 HydrophobicContact CD1-CD1 4Å; L143-I147 HydrophobicContact CD1-CG1 4.3Å; L143-I147 HydrophobicContact CG-CD1 3.97Å; L143-I147 WeakPolarHBondContact O-CG1 3.48Å; L143-I147 PolarHBondContact O-N 3.17Å; L143-L167 HydrophobicContact CD2-CB 4Å; L143-L167 HydrophobicContact CD2-CD1 4.45Å; L143-L167 HydrophobicContact CG-CD1 4.27Å; L143-V171 HydrophobicContact CD2-CG2 3.65Å; L143-L337 HydrophobicContact CB-CD1 4.43Å; L143-L337 HydrophobicContact CB-CD2 4.24Å; L143-L337 HydrophobicContact CD1-CD1 4.09Å
144	P	90.5	Very high	86.5	Confident	15 Å²	15	33.4 Å²	33.4	10%	0.097	20%	0.203	C	C	.	.	H	α-helix	trans	-59.9	-41.8	176.1	-21.4	32.9	0	0	0	111.8	K140 A146 I147 S148 L167	K140-P144 WeakPolarHBondContact O-CD 3.46Å; P144-A146 VanDerWaalsContact C-N 3.34Å; P144-A146 PolarHBondContact O-N 2.76Å; P144-I147 PolarHBondContact O-N 2.91Å; P144-S148 WeakPolarHBondContact O-CB 3.39Å; P144-S148 PolarHBondContact O-N 3.26Å; P144-S148 PolarHBondContact O-OG 3.35Å; P144-L167 HydrophobicContact CB-CD1 4.24Å; P144-L167 HydrophobicContact CG-CD1 3.98Å
145	A	86	Confident	84.5	Confident	25 Å²	25	41.4 Å²	41.4	21%	0.207	25%	0.246	C	C	.	.	H	α-helix	trans	-67.6	-33.4	180	0	0	0	0	0	112.6	E142 L143 S148 S149	E142-A145 PolarHBondContact O-N 2.91Å; L143-A145 VanDerWaalsContact C-N 3.28Å; L143-A145 PolarHBondContact O-N 3.35Å; A145-S148 PolarHBondContact O-OG 2.94Å; A145-S149 VanDerWaalsContact O-CB 3.28Å; A145-S149 WeakPolarHBondContact O-CB 3.17Å; A145-S149 PolarHBondContact O-N 3.01Å
146	A	88.5	Confident	82.5	Confident	2 Å²	2	45.4 Å²	45.4	2%	0.017	27%	0.271	C	S	.	.	H	α-helix	trans	-69.8	-42.7	174.2	0	0	0	0	0	111.8	E142 L143 P144 L150 R333 L334 L337	E142-A146 WeakPolarHBondContact O-CB 3.48Å; E142-A146 PolarHBondContact O-N 2.84Å; L143-A146 PolarHBondContact O-N 3.4Å; P144-A146 VanDerWaalsContact C-N 3.34Å; P144-A146 PolarHBondContact O-N 2.76Å; A146-L150 WeakPolarHBondContact O-CB 3.38Å; A146-L150 PolarHBondContact O-N 3.04Å; A146-L150 VanDerWaalsContact O-N 3.11Å; A146-R333 HydrophobicContact CB-CB 4.5Å; A146-L334 HydrophobicContact CB-CD2 4.05Å; A146-L337 HydrophobicContact CB-CD1 3.86Å
147	I	88.6	Confident	80.9	Confident	45 Å²	45	48.5 Å²	48.5	23%	0.231	30%	0.304	C	S	.	.	H	α-helix	trans	-67.5	-48	179.5	-67.6	168.6	0	0	0	110.9	L143 P144 S149 L150 L151 Y161 L167	L143-I147 HydrophobicContact CD1-CD1 4Å; L143-I147 HydrophobicContact CD1-CG1 4.3Å; L143-I147 HydrophobicContact CG-CD1 3.97Å; L143-I147 WeakPolarHBondContact O-CG1 3.48Å; L143-I147 PolarHBondContact O-N 3.17Å; P144-I147 PolarHBondContact O-N 2.91Å; I147-S149 VanDerWaalsContact C-N 3.28Å; I147-S149 PolarHBondContact O-N 3.43Å; I147-L150 PolarHBondContact O-N 3.17Å; I147-L150 VanDerWaalsContact O-N 3.12Å; I147-L151 HydrophobicContact CG2-CD1 3.55Å; I147-L151 HydrophobicContact CG2-CG 4.25Å; I147-L151 WeakPolarHBondContact O-CG 3.32Å; I147-L151 PolarHBondContact O-N 3.38Å; I147-Y161 HydrophobicContact CG2-CD2 3.9Å; I147-Y161 HydrophobicContact CG2-CG 4.03Å; I147-L167 HydrophobicContact CD1-CD1 3.79Å; I147-L167 HydrophobicContact CD1-CD2 4.15Å
148	S	84.6	Confident	79.5	Confident	40 Å²	40	57.1 Å²	57.1	28%	0.28	34%	0.344	S	S	.	.	H	α-helix	trans	-60.8	-39.3	179.7	64.9	0	0	0	0	111.9	P144 A145 L150 N152	P144-S148 WeakPolarHBondContact O-CB 3.39Å; P144-S148 PolarHBondContact O-N 3.26Å; P144-S148 PolarHBondContact O-OG 3.35Å; A145-S148 PolarHBondContact O-OG 2.94Å; S148-L150 PolarHBondContact O-N 2.7Å; S148-N152 PolarHBondContact O-N 2.97Å
149	S	83.1	Confident	78.9	Confident	10 Å²	10	58 Å²	58	7%	0.07	35%	0.352	C	S	.	.	H	α-helix	trans	-72.2	-25	177.2	-168.1	0	0	0	0	114.2	A145 I147 P324 I330	A145-S149 VanDerWaalsContact O-CB 3.28Å; A145-S149 WeakPolarHBondContact O-CB 3.17Å; A145-S149 PolarHBondContact O-N 3.01Å; I147-S149 VanDerWaalsContact C-N 3.28Å; I147-S149 PolarHBondContact O-N 3.43Å; S149-P324 PolarHBondContact OG-O 3.12Å; S149-I330 WeakPolarHBondContact OG-CD1 3.38Å; S149-I330 WeakPolarHBondContact OG-CG1 3.33Å
150	L	83.3	Confident	78.4	Confident	123 Å²	123	65.6 Å²	65.6	64%	0.644	38%	0.38	S	S	*	.	H	α-helix	trans	-80.8	-37.6	176.1	-179.5	62.7	0	0	0	111.7	A146 I147 S148 N152	A146-L150 WeakPolarHBondContact O-CB 3.38Å; A146-L150 PolarHBondContact O-N 3.04Å; A146-L150 VanDerWaalsContact O-N 3.11Å; I147-L150 PolarHBondContact O-N 3.17Å; I147-L150 VanDerWaalsContact O-N 3.12Å; S148-L150 PolarHBondContact O-N 2.7Å; L150-N152 PolarHBondContact O-N 3.38Å
151	L	81.6	Confident	77.9	Confident	99 Å²	99	65.6 Å²	65.6	52%	0.518	38%	0.379	S	S	.	.	H	α-helix	trans	-76.3	-8.6	-177.2	-70.2	173.3	0	0	0	113.4	I147 A153 Y161	I147-L151 HydrophobicContact CG2-CD1 3.55Å; I147-L151 HydrophobicContact CG2-CG 4.25Å; I147-L151 WeakPolarHBondContact O-CG 3.32Å; I147-L151 PolarHBondContact O-N 3.38Å; L151-A153 HydrophobicContact CB-CB 4.12Å; L151-A153 PolarHBondContact O-N 3.23Å; L151-Y161 HydrophobicContact CD1-CD1 4.38Å; L151-Y161 HydrophobicContact CD1-CD2 4.45Å; L151-Y161 HydrophobicContact CD1-CE1 4.13Å; L151-Y161 HydrophobicContact CD1-CE2 4.26Å
152	N	70.8	Confident	77.5	Confident	140 Å²	140	68.2 Å²	68.2	75%	0.749	39%	0.389	S	S	*	.	T	Hydrogen-bonded Turn	trans	44.6	33	-169.9	-72.8	-23.7	0	0	0	111.6	S148 L150 G154	S148-N152 PolarHBondContact O-N 2.97Å; L150-N152 PolarHBondContact O-N 3.38Å; N152-G154 VanDerWaalsContact C-N 3.34Å; N152-G154 PolarHBondContact O-N 3.5Å
153	A	60.8	Low	77.4	Confident	32 Å²	32	71.8 Å²	71.8	26%	0.264	41%	0.408	S	S	.	.			trans	-70.9	94.8	-172.9	0	0	0	0	0	107.7	L151 N155 Y161	L151-A153 HydrophobicContact CB-CB 4.12Å; L151-A153 PolarHBondContact O-N 3.23Å; A153-N155 PolarHBondContact O-N 2.87Å; A153-N155 VanDerWaalsContact O-N 3.11Å; A153-Y161 WeakPolarHBondContact CB-OH 3.29Å
154	G	57	Low	77.3	Confident	60 Å²	60	71 Å²	71	62%	0.619	41%	0.406	S	S	*	.			trans	-62.5	113.5	174.3	0	0	0	0	0	108.9	N152 T156	N152-G154 VanDerWaalsContact C-N 3.34Å; N152-G154 PolarHBondContact O-N 3.5Å; G154-T156 PolarHBondContact O-N 3.2Å
155	N	54.9	Low	77.4	Confident	169 Å²	169	77.2 Å²	77.2	90%	0.904	43%	0.428	S	S	*	.	S	Bend	trans	29.7	35.7	161.2	-126.1	50.8	0	0	0	118.8	A153 G157	A153-N155 PolarHBondContact O-N 2.87Å; A153-N155 VanDerWaalsContact O-N 3.11Å; N155-G157 PolarHBondContact O-N 3.01Å
156	T	52.4	Low	77.8	Confident	89 Å²	89	79.2 Å²	79.2	55%	0.546	44%	0.435	S	S	.	.			trans	-84.5	99	169	51.7	0	0	0	0	106.6	G154	G154-T156 PolarHBondContact O-N 3.2Å
157	G	61.3	Low	78	Confident	67 Å²	67	79.5 Å²	79.5	69%	0.691	44%	0.436	S	S	*	.			trans	-54.9	160.6	-168.9	0	0	0	0	0	116.3	N155 A159	N155-G157 PolarHBondContact O-N 3.01Å; G157-A159 VanDerWaalsContact C-N 3.3Å; G157-A159 PolarHBondContact O-N 3.37Å; G157-A159 VanDerWaalsContact O-N 3.15Å
158	H	66.1	Low	78.3	Confident	193 Å²	193	77.4 Å²	77.4	89%	0.894	43%	0.425	S	S	*	.	S	Bend	trans	42.9	44.8	172	-70.8	-60.2	0	0	0	115.6
159	A	80.9	Confident	78.8	Confident	20 Å²	20	79.1 Å²	79.1	17%	0.165	43%	0.431	C	S	.	.			trans	-70.9	143.2	170.8	0	0	0	0	0	110.7	G157 Y161 E162	G157-A159 VanDerWaalsContact C-N 3.3Å; G157-A159 PolarHBondContact O-N 3.37Å; G157-A159 VanDerWaalsContact O-N 3.15Å; A159-Y161 HydrophobicContact CB-CD1 3.79Å; A159-Y161 HydrophobicContact CB-CD2 4.22Å; A159-Y161 HydrophobicContact CB-CE1 3.33Å; A159-Y161 HydrophobicContact CB-CE2 3.78Å; A159-Y161 HydrophobicContact CB-CG 4.21Å; A159-Y161 PolarHBondContact O-N 3.48Å; A159-Y161 VanDerWaalsContact O-N 3.11Å; A159-E162 HydrophobicContact CB-CG 4.25Å; A159-E162 WeakPolarHBondContact O-CB 3.43Å; A159-E162 PolarHBondContact O-N 2.99Å
160	W	85.1	Confident	79.4	Confident	160 Å²	160	81.9 Å²	81.9	61%	0.606	44%	0.444	S	S	*	.	G	3₁₀ helix	trans	-58.9	-27.1	-178.7	66.2	-91.5	0	0	0	113.2	E162 D163 L166 L167 I170	W160-E162 VanDerWaalsContact C-N 3.27Å; W160-E162 PolarHBondContact O-N 3.43Å; W160-D163 PolarHBondContact O-N 3.05Å; W160-L166 HydrophobicContact CB-CD2 3.94Å; W160-L166 HydrophobicContact CE3-CD2 4.39Å; W160-L167 HydrophobicContact CE3-CD2 4.22Å; W160-L167 HydrophobicContact CZ3-CD2 3.65Å; W160-I170 HydrophobicContact CE3-CD1 4.5Å; W160-I170 HydrophobicContact CZ3-CD1 4.21Å
161	Y	83.1	Confident	79.9	Confident	31 Å²	31	77.2 Å²	77.2	12%	0.122	42%	0.42	C	S	.	.	G	3₁₀ helix	trans	-79.8	-3.7	177.4	60.8	-105.7	0	0	0	113.7	I147 L151 A153 A159 L167	I147-Y161 HydrophobicContact CG2-CD2 3.9Å; I147-Y161 HydrophobicContact CG2-CG 4.03Å; L151-Y161 HydrophobicContact CD1-CD1 4.38Å; L151-Y161 HydrophobicContact CD1-CD2 4.45Å; L151-Y161 HydrophobicContact CD1-CE1 4.13Å; L151-Y161 HydrophobicContact CD1-CE2 4.26Å; A153-Y161 WeakPolarHBondContact CB-OH 3.29Å; A159-Y161 HydrophobicContact CB-CD1 3.79Å; A159-Y161 HydrophobicContact CB-CD2 4.22Å; A159-Y161 HydrophobicContact CB-CE1 3.33Å; A159-Y161 HydrophobicContact CB-CE2 3.78Å; A159-Y161 HydrophobicContact CB-CG 4.21Å; A159-Y161 PolarHBondContact O-N 3.48Å; A159-Y161 VanDerWaalsContact O-N 3.11Å; Y161-L167 WeakPolarHBondContact O-CD1 3.31Å
162	E	84.3	Confident	80.5	Confident	84 Å²	84	72.8 Å²	72.8	39%	0.393	40%	0.397	S	S	.	.	G	3₁₀ helix	trans	-88.9	-18.2	171.5	-63	-179.4	160.6	0	0	111.5	A159 W160 G164	A159-E162 HydrophobicContact CB-CG 4.25Å; A159-E162 WeakPolarHBondContact O-CB 3.43Å; A159-E162 PolarHBondContact O-N 2.99Å; W160-E162 VanDerWaalsContact C-N 3.27Å; W160-E162 PolarHBondContact O-N 3.43Å; E162-G164 PolarHBondContact O-N 3.32Å
163	D	89.6	Confident	81.6	Confident	76 Å²	76	71.5 Å²	71.5	41%	0.406	39%	0.39	S	S	.	.			trans	-80.5	99.5	174.5	-172.9	-6.6	0	0	0	111.2	W160 R165 L166 L167	W160-D163 PolarHBondContact O-N 3.05Å; D163-R165 PolarHBondContact O-N 3.01Å; D163-R165 WeakPolarHBondContact OD1-CB 3.18Å; D163-R165 PolarHBondContact OD1-N 3.07Å; D163-L166 HydrophobicContact CB-CB 4.03Å; D163-L166 PolarHBondContact O-N 3.33Å; D163-L166 PolarHBondContact OD1-N 3.3Å; D163-L167 PolarHBondContact O-N 3.02Å
164	G	90.5	Very high	83.2	Confident	11 Å²	11	74.1 Å²	74.1	11%	0.113	41%	0.405	C	S	.	.	H	α-helix	trans	-59	-25.9	176.2	0	0	0	0	0	114.7	K140 E162 L168	K140-G164 WeakPolarHBondContact O-CA 3.42Å; E162-G164 PolarHBondContact O-N 3.32Å; G164-L168 WeakPolarHBondContact O-CB 3.3Å; G164-L168 PolarHBondContact O-N 2.85Å
165	R	93.7	Very high	84.8	Confident	146 Å²	146	73.9 Å²	73.9	55%	0.551	39%	0.391	S	S	*	.	H	α-helix	trans	-72.8	-45.8	177	-55.4	-178.6	-163.6	-157.7	4.6	110.4	D163 L168 I169	D163-R165 PolarHBondContact O-N 3.01Å; D163-R165 WeakPolarHBondContact OD1-CB 3.18Å; D163-R165 PolarHBondContact OD1-N 3.07Å; R165-L168 PolarHBondContact O-N 2.72Å; R165-I169 WeakPolarHBondContact O-CG1 3.38Å; R165-I169 PolarHBondContact O-N 3.17Å; R165-I169 VanDerWaalsContact O-N 3.1Å
166	L	93.1	Very high	86.6	Confident	67 Å²	67	65.9 Å²	65.9	35%	0.351	35%	0.349	S	S	.	.	H	α-helix	trans	-62	-48.4	177.6	-179.7	63.7	0	0	0	110.9	W160 D163 L168 I169 I170	W160-L166 HydrophobicContact CB-CD2 3.94Å; W160-L166 HydrophobicContact CE3-CD2 4.39Å; D163-L166 HydrophobicContact CB-CB 4.03Å; D163-L166 PolarHBondContact O-N 3.33Å; D163-L166 PolarHBondContact OD1-N 3.3Å; L166-L168 VanDerWaalsContact C-N 3.33Å; L166-L168 PolarHBondContact O-N 2.98Å; L166-I169 PolarHBondContact O-N 2.97Å; L166-I170 HydrophobicContact CD1-CD1 4.25Å; L166-I170 HydrophobicContact CG-CD1 4Å; L166-I170 WeakPolarHBondContact O-CG1 3.45Å; L166-I170 PolarHBondContact O-N 3.39Å
167	L	93.2	Very high	88.6	Confident	8 Å²	8	62.6 Å²	62.6	4%	0.042	33%	0.328	C	S	.	.	H	α-helix	trans	-61.1	-40.8	177.6	-76.4	177.5	0	0	0	112.6	L143 P144 I147 W160 Y161 D163 I169 I170 V171	L143-L167 HydrophobicContact CD2-CB 4Å; L143-L167 HydrophobicContact CD2-CD1 4.45Å; L143-L167 HydrophobicContact CG-CD1 4.27Å; P144-L167 HydrophobicContact CB-CD1 4.24Å; P144-L167 HydrophobicContact CG-CD1 3.98Å; I147-L167 HydrophobicContact CD1-CD1 3.79Å; I147-L167 HydrophobicContact CD1-CD2 4.15Å; W160-L167 HydrophobicContact CE3-CD2 4.22Å; W160-L167 HydrophobicContact CZ3-CD2 3.65Å; Y161-L167 WeakPolarHBondContact O-CD1 3.31Å; D163-L167 PolarHBondContact O-N 3.02Å; L167-I169 VanDerWaalsContact C-N 3.34Å; L167-I169 PolarHBondContact O-N 3.39Å; L167-I170 PolarHBondContact O-N 2.88Å; L167-V171 WeakPolarHBondContact O-CB 3.36Å; L167-V171 WeakPolarHBondContact O-CG2 3.4Å; L167-V171 PolarHBondContact O-N 3.05Å
168	L	94.9	Very high	90	Very high	0 Å²	0	62.6 Å²	62.6	0%	0	32%	0.317	C	S	.	.	H	α-helix	trans	-59.8	-44.3	176	179.5	66.3	0	0	0	111.6	L136 L139 K140 G164 R165 L166 T172 L382 A385 I386	L136-L168 HydrophobicContact CB-CD1 3.94Å; L136-L168 HydrophobicContact CB-CD2 4.48Å; L136-L168 HydrophobicContact CD1-CD1 4.39Å; L136-L168 HydrophobicContact CD2-CD1 4.19Å; L136-L168 HydrophobicContact CG-CD1 4.38Å; L136-L168 WeakPolarHBondContact O-CD1 3.43Å; L139-L168 HydrophobicContact CB-CD1 3.9Å; L139-L168 HydrophobicContact CD1-CD1 4.43Å; K140-L168 HydrophobicContact CB-CD2 4.18Å; K140-L168 HydrophobicContact CG-CD2 4.46Å; G164-L168 WeakPolarHBondContact O-CB 3.3Å; G164-L168 PolarHBondContact O-N 2.85Å; R165-L168 PolarHBondContact O-N 2.72Å; L166-L168 VanDerWaalsContact C-N 3.33Å; L166-L168 PolarHBondContact O-N 2.98Å; L168-T172 VanDerWaalsContact O-CB 3.25Å; L168-T172 WeakPolarHBondContact O-CB 3.39Å; L168-T172 PolarHBondContact O-N 3.49Å; L168-T172 PolarHBondContact O-OG1 3.04Å; L168-L382 HydrophobicContact CD2-CD1 3.62Å; L168-L382 HydrophobicContact CG-CD1 3.67Å; L168-A385 HydrophobicContact CD2-CB 3.99Å; L168-I386 HydrophobicContact CD2-CG1 4.11Å
169	I	95.3	Very high	91.1	Very high	77 Å²	77	56.8 Å²	56.8	40%	0.395	29%	0.292	S	S	.	.	H	α-helix	trans	-62	-47.6	178.1	-67.3	165.1	0	0	0	110.3	R165 L166 L167 T172 L173 L382 I386	R165-I169 WeakPolarHBondContact O-CG1 3.38Å; R165-I169 PolarHBondContact O-N 3.17Å; R165-I169 VanDerWaalsContact O-N 3.1Å; L166-I169 PolarHBondContact O-N 2.97Å; L167-I169 VanDerWaalsContact C-N 3.34Å; L167-I169 PolarHBondContact O-N 3.39Å; I169-T172 PolarHBondContact O-N 2.92Å; I169-L173 WeakPolarHBondContact O-CB 3.48Å; I169-L173 PolarHBondContact O-N 3Å; I169-L382 HydrophobicContact CG1-CD2 4.4Å; I169-I386 HydrophobicContact CD1-CD1 4.37Å; I169-I386 HydrophobicContact CG1-CD1 4.28Å
170	I	94.8	Very high	91.4	Very high	68 Å²	68	56 Å²	56	35%	0.349	29%	0.285	S	S	.	.	H	α-helix	trans	-59.5	-51.7	179.8	-67.5	167.8	0	0	0	110.7	W160 L166 L167 T172 L173 C174	W160-I170 HydrophobicContact CE3-CD1 4.5Å; W160-I170 HydrophobicContact CZ3-CD1 4.21Å; L166-I170 HydrophobicContact CD1-CD1 4.25Å; L166-I170 HydrophobicContact CG-CD1 4Å; L166-I170 WeakPolarHBondContact O-CG1 3.45Å; L166-I170 PolarHBondContact O-N 3.39Å; L167-I170 PolarHBondContact O-N 2.88Å; I170-T172 VanDerWaalsContact C-N 3.31Å; I170-T172 PolarHBondContact O-N 3.29Å; I170-L173 PolarHBondContact O-N 2.92Å; I170-C174 VanDerWaalsContact O-CB 3.28Å; I170-C174 WeakPolarHBondContact O-CB 3.35Å; I170-C174 PolarHBondContact O-N 3.3Å; I170-C174 PolarHBondContact O-SG 3.42Å; I170-C174 VanDerWaalsContact O-SG 3.42Å
171	V	94.4	Very high	91.4	Very high	25 Å²	25	51 Å²	51	15%	0.152	27%	0.269	C	S	.	.	H	α-helix	trans	-64.6	-38.2	-179.1	171.6	0	0	0	0	111.4	L139 L143 L167 V175 I176 L341	L139-V171 HydrophobicContact CD1-CG1 4.49Å; L143-V171 HydrophobicContact CD2-CG2 3.65Å; L167-V171 WeakPolarHBondContact O-CB 3.36Å; L167-V171 WeakPolarHBondContact O-CG2 3.4Å; L167-V171 PolarHBondContact O-N 3.05Å; V171-V175 HydrophobicContact CG1-CB 4.37Å; V171-V175 HydrophobicContact CG1-CG2 4.44Å; V171-V175 WeakPolarHBondContact O-CA 3.25Å; V171-V175 VanDerWaalsContact O-CB 3.29Å; V171-V175 WeakPolarHBondContact O-CB 3.44Å; V171-V175 PolarHBondContact O-N 3.38Å; V171-I176 PolarHBondContact O-N 3.03Å; V171-L341 HydrophobicContact CG1-CD2 3.53Å
172	T	94.3	Very high	91.4	Very high	6 Å²	6	52 Å²	52	4%	0.037	28%	0.281	C	S	.	.	I	π-helix	trans	-62.7	-47	177.1	-57.9	0	0	0	0	111	L168 I169 I170 I176 V177 L382	L168-T172 VanDerWaalsContact O-CB 3.25Å; L168-T172 WeakPolarHBondContact O-CB 3.39Å; L168-T172 PolarHBondContact O-N 3.49Å; L168-T172 PolarHBondContact O-OG1 3.04Å; I169-T172 PolarHBondContact O-N 2.92Å; I170-T172 VanDerWaalsContact C-N 3.31Å; I170-T172 PolarHBondContact O-N 3.29Å; T172-I176 HydrophobicContact CG2-CB 4.41Å; T172-I176 PolarHBondContact O-N 2.69Å; T172-V177 HydrophobicContact CG2-CG2 4.48Å; T172-V177 WeakPolarHBondContact O-CG2 3.43Å; T172-V177 PolarHBondContact O-N 3.33Å; T172-L382 HydrophobicContact CG2-CD2 4.46Å
173	L	94.1	Very high	90.5	Very high	113 Å²	113	51.1 Å²	51.1	59%	0.592	28%	0.282	S	S	*	.	I	π-helix	trans	-71	-43.1	-178.4	-175.7	64.6	0	0	0	112.8	I169 I170 P178	I169-L173 WeakPolarHBondContact O-CB 3.48Å; I169-L173 PolarHBondContact O-N 3Å; I170-L173 PolarHBondContact O-N 2.92Å; L173-P178 VanDerWaalsContact O-CD 3.32Å; L173-P178 WeakPolarHBondContact O-CD 3.08Å
174	C	93.7	Very high	89.2	Confident	86 Å²	86	56 Å²	56	58%	0.581	30%	0.3	S	S	*	.	I	π-helix	trans	-87.2	-23.8	-172.4	-64	0	0	0	0	113.9	I170	I170-C174 VanDerWaalsContact O-CB 3.28Å; I170-C174 WeakPolarHBondContact O-CB 3.35Å; I170-C174 PolarHBondContact O-N 3.3Å; I170-C174 PolarHBondContact O-SG 3.42Å; I170-C174 VanDerWaalsContact O-SG 3.42Å
175	V	92	Very high	87.8	Confident	55 Å²	55	58.9 Å²	58.9	33%	0.333	31%	0.312	S	S	.	.	I	π-helix	trans	-120.1	-57	-175.3	-173.7	0	0	0	0	111.1	V171 P178 L179	V171-V175 HydrophobicContact CG1-CB 4.37Å; V171-V175 HydrophobicContact CG1-CG2 4.44Å; V171-V175 WeakPolarHBondContact O-CA 3.25Å; V171-V175 VanDerWaalsContact O-CB 3.29Å; V171-V175 WeakPolarHBondContact O-CB 3.44Å; V171-V175 PolarHBondContact O-N 3.38Å; V175-P178 WeakPolarHBondContact O-CD 3.26Å; V175-L179 WeakPolarHBondContact O-CB 3.39Å; V175-L179 VanDerWaalsContact O-CD1 3.31Å; V175-L179 WeakPolarHBondContact O-CD1 3.48Å; V175-L179 PolarHBondContact O-N 3.45Å
176	I	93	Very high	85.9	Confident	1 Å²	1	55.1 Å²	55.1	1%	0.005	32%	0.319	C	S	.	.	I	π-helix	trans	-69.7	-45.8	-169.9	-56.9	-179.1	0	0	0	111.7	L136 L139 V171 T172 L179 A180 L341 V344 L378	L136-I176 HydrophobicContact CD2-CD1 3.4Å; L139-I176 HydrophobicContact CD1-CD1 3.91Å; V171-I176 PolarHBondContact O-N 3.03Å; T172-I176 HydrophobicContact CG2-CB 4.41Å; T172-I176 PolarHBondContact O-N 2.69Å; I176-L179 PolarHBondContact O-N 3.21Å; I176-A180 VanDerWaalsContact O-CB 3.22Å; I176-A180 WeakPolarHBondContact O-CB 3.32Å; I176-A180 PolarHBondContact O-N 3.41Å; I176-L341 HydrophobicContact CD1-CD2 4.19Å; I176-L341 HydrophobicContact CG1-CD2 4.05Å; I176-V344 HydrophobicContact CG2-CB 4.46Å; I176-V344 HydrophobicContact CG2-CG1 3.6Å; I176-L378 HydrophobicContact CG2-CD1 4.35Å; I176-L378 HydrophobicContact CG2-CD2 4.1Å
177	V	92.7	Very high	84.1	Confident	20 Å²	20	60.1 Å²	60.1	12%	0.121	34%	0.338	C	S	.	.	H	α-helix	trans	-60.2	-51.3	179.8	167	0	0	0	0	111.5	T172 L179 A180 M181 L375 L378	T172-V177 HydrophobicContact CG2-CG2 4.48Å; T172-V177 WeakPolarHBondContact O-CG2 3.43Å; T172-V177 PolarHBondContact O-N 3.33Å; V177-L179 VanDerWaalsContact C-N 3.33Å; V177-L179 PolarHBondContact O-N 3.1Å; V177-A180 PolarHBondContact O-N 2.89Å; V177-M181 HydrophobicContact CG1-CG 4.36Å; V177-M181 HydrophobicContact CG1-SD 3.87Å; V177-M181 WeakPolarHBondContact O-CB 3.32Å; V177-M181 VanDerWaalsContact O-CG 3.27Å; V177-M181 WeakPolarHBondContact O-CG 3.39Å; V177-M181 PolarHBondContact O-N 3.4Å; V177-L375 HydrophobicContact CG1-CD2 4.24Å; V177-L378 HydrophobicContact CB-CD1 4.46Å; V177-L378 HydrophobicContact CG2-CD1 3.72Å
178	P	91.1	Very high	82.4	Confident	68 Å²	68	61.7 Å²	61.7	44%	0.442	35%	0.346	S	S	.	.	H	α-helix	trans	-56.6	-43.5	175.6	-28	35.2	0	0	0	113.4	L173 V175 M181	L173-P178 VanDerWaalsContact O-CD 3.32Å; L173-P178 WeakPolarHBondContact O-CD 3.08Å; V175-P178 WeakPolarHBondContact O-CD 3.26Å; P178-M181 PolarHBondContact O-N 3.28Å
179	L	88.6	Confident	81	Confident	71 Å²	71	63 Å²	63	37%	0.372	36%	0.36	S	S	.	.	H	α-helix	trans	-66.1	-42.8	178.8	-93.6	63.3	0	0	0	111.8	V175 I176 V177 M181 S182 P345	V175-L179 WeakPolarHBondContact O-CB 3.39Å; V175-L179 VanDerWaalsContact O-CD1 3.31Å; V175-L179 WeakPolarHBondContact O-CD1 3.48Å; V175-L179 PolarHBondContact O-N 3.45Å; I176-L179 PolarHBondContact O-N 3.21Å; V177-L179 VanDerWaalsContact C-N 3.33Å; V177-L179 PolarHBondContact O-N 3.1Å; L179-M181 VanDerWaalsContact C-N 3.31Å; L179-M181 PolarHBondContact O-N 2.94Å; L179-S182 WeakPolarHBondContact O-CB 3.34Å; L179-S182 PolarHBondContact O-N 2.91Å; L179-S182 PolarHBondContact O-OG 3.25Å; L179-P345 HydrophobicContact CB-CB 4.34Å; L179-P345 HydrophobicContact CB-CG 3.72Å; L179-P345 HydrophobicContact CD2-CG 4.2Å
180	A	87.8	Confident	80.1	Confident	3 Å²	3	68.5 Å²	68.5	3%	0.025	38%	0.376	C	S	.	.	H	α-helix	trans	-70	-26.1	180	0	0	0	0	0	113.1	I176 V177 S182 R352 T374 L378	I176-A180 VanDerWaalsContact O-CB 3.22Å; I176-A180 WeakPolarHBondContact O-CB 3.32Å; I176-A180 PolarHBondContact O-N 3.41Å; V177-A180 PolarHBondContact O-N 2.89Å; A180-S182 PolarHBondContact O-N 3.42Å; A180-R352 PolarHBondContact O-NH1 2.9Å; A180-T374 HydrophobicContact CB-CG2 4.04Å; A180-L378 HydrophobicContact CB-CD1 3.9Å
181	M	86.2	Confident	79.5	Confident	55 Å²	55	66.2 Å²	66.2	27%	0.271	37%	0.365	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.1	-7.3	175	-75.8	-174.8	58.9	0	0	113.8	V177 P178 L179 P183 I371 T374	V177-M181 HydrophobicContact CG1-CG 4.36Å; V177-M181 HydrophobicContact CG1-SD 3.87Å; V177-M181 WeakPolarHBondContact O-CB 3.32Å; V177-M181 VanDerWaalsContact O-CG 3.27Å; V177-M181 WeakPolarHBondContact O-CG 3.39Å; V177-M181 PolarHBondContact O-N 3.4Å; P178-M181 PolarHBondContact O-N 3.28Å; L179-M181 VanDerWaalsContact C-N 3.31Å; L179-M181 PolarHBondContact O-N 2.94Å; M181-P183 WeakPolarHBondContact O-CD 3.4Å; M181-I371 HydrophobicContact CE-CD1 4.24Å; M181-I371 HydrophobicContact CE-CG1 3.75Å; M181-T374 HydrophobicContact CG-CG2 4.07Å
182	S	81.3	Confident	79.1	Confident	53 Å²	53	65.1 Å²	65.1	37%	0.371	36%	0.358	S	S	.	.			trans	-65.7	127.4	177.4	66	0	0	0	0	111.3	L179 A180	L179-S182 WeakPolarHBondContact O-CB 3.34Å; L179-S182 PolarHBondContact O-N 2.91Å; L179-S182 PolarHBondContact O-OG 3.25Å; A180-S182 PolarHBondContact O-N 3.42Å
183	P	66.9	Low	78.8	Confident	65 Å²	65	66.3 Å²	66.3	42%	0.422	37%	0.367	S	S	.	.	S	Bend	trans	-81.4	-21.4	-176.9	28.9	-33.7	0	0	0	113.4	M181 W367	M181-P183 WeakPolarHBondContact O-CD 3.4Å; P183-W367 HydrophobicContact CG-CH2 4.23Å
184	K	62.6	Low	78.6	Confident	179 Å²	179	62.6 Å²	62.6	78%	0.778	35%	0.348	S	S	*	.			trans	-120.4	128	-177.3	-66.1	-175.2	-177.8	179.7	0	111.1	G186	K184-G186 VanDerWaalsContact C-N 3.34Å; K184-G186 PolarHBondContact O-N 2.92Å; K184-G186 VanDerWaalsContact O-N 3.17Å
185	I	60.5	Low	78.3	Confident	71 Å²	71	58.5 Å²	58.5	36%	0.364	32%	0.32	S	S	.	.			trans	-88.9	73.5	175.5	-66.4	171.1	0	0	0	108.9	L188 F349	I185-L188 HydrophobicContact CG2-CB 3.57Å; I185-L188 HydrophobicContact CG2-CD1 3.18Å; I185-L188 HydrophobicContact CG2-CD2 3.55Å; I185-L188 HydrophobicContact CG2-CG 3.58Å; I185-F349 HydrophobicContact CD1-CB 3.98Å; I185-F349 HydrophobicContact CD1-CD1 3.78Å; I185-F349 HydrophobicContact CD1-CD2 3.57Å; I185-F349 HydrophobicContact CD1-CE1 4.11Å; I185-F349 HydrophobicContact CD1-CE2 3.92Å; I185-F349 HydrophobicContact CD1-CG 3.5Å; I185-F349 HydrophobicContact CD1-CZ 4.18Å; I185-F349 HydrophobicContact CG1-CD2 4.27Å; I185-F349 HydrophobicContact CG1-CE2 4.48Å
186	G	52.9	Low	78.3	Confident	67 Å²	67	57.5 Å²	57.5	69%	0.691	31%	0.311	S	S	*	.			trans	-87.6	-10.7	178.8	0	0	0	0	0	114.7	K184	K184-G186 VanDerWaalsContact C-N 3.34Å; K184-G186 PolarHBondContact O-N 2.92Å; K184-G186 VanDerWaalsContact O-N 3.17Å
187	F	56.6	Low	78.3	Confident	172 Å²	172	62 Å²	62	75%	0.754	33%	0.334	S	S	*	.	S	Bend	trans	-109	0.6	-168.3	-74	-86.7	0	0	0	114.5	G189 T191	F187-G189 PolarHBondContact O-N 2.91Å; F187-T191 PolarHBondContact O-N 3.47Å; F187-T191 PolarHBondContact O-OG1 3.11Å
188	L	56.9	Low	78.3	Confident	40 Å²	40	62.7 Å²	62.7	21%	0.209	34%	0.336	C	S	.	.	H	α-helix	trans	-67.8	-38.8	-162.5	-125.5	61.7	0	0	0	116.6	I185 W190 T191 S192 L346	I185-L188 HydrophobicContact CG2-CB 3.57Å; I185-L188 HydrophobicContact CG2-CD1 3.18Å; I185-L188 HydrophobicContact CG2-CD2 3.55Å; I185-L188 HydrophobicContact CG2-CG 3.58Å; L188-W190 VanDerWaalsContact C-N 3.27Å; L188-W190 PolarHBondContact O-N 2.98Å; L188-T191 WeakPolarHBondContact CA-OG1 3.38Å; L188-T191 PolarHBondContact O-N 3.42Å; L188-T191 PolarHBondContact O-OG1 2.98Å; L188-T191 VanDerWaalsContact O-OG1 3.05Å; L188-S192 PolarHBondContact O-N 3.47Å; L188-S192 PolarHBondContact O-OG 3.36Å; L188-S192 VanDerWaalsContact O-OG 3.12Å; L188-L346 HydrophobicContact CD1-CD1 4.1Å; L188-L346 HydrophobicContact CD1-CD2 3.08Å; L188-L346 HydrophobicContact CD1-CG 4.18Å; L188-L346 HydrophobicContact CD2-CD2 4.38Å; L188-L346 HydrophobicContact CG-CD1 4.27Å; L188-L346 HydrophobicContact CG-CD2 4.03Å
189	G	65.4	Low	78.4	Confident	29 Å²	29	59.9 Å²	59.9	30%	0.299	32%	0.317	S	S	.	.	H	α-helix	trans	-60.7	-40.2	-174.6	0	0	0	0	0	112	F187 S193	F187-G189 PolarHBondContact O-N 2.91Å; G189-S193 PolarHBondContact O-N 3.5Å; G189-S193 PolarHBondContact O-OG 2.93Å
190	W	76.4	Confident	78.6	Confident	191 Å²	191	60 Å²	60	72%	0.723	32%	0.318	S	S	*	.	H	α-helix	trans	-78.4	-38.3	-179.7	-170.1	71.2	0	0	0	112.4	L188 S192 S193 L194	L188-W190 VanDerWaalsContact C-N 3.27Å; L188-W190 PolarHBondContact O-N 2.98Å; W190-S192 PolarHBondContact O-N 3.35Å; W190-S193 PolarHBondContact O-N 2.96Å; W190-L194 HydrophobicContact CH2-CD2 4.26Å; W190-L194 HydrophobicContact CZ3-CD2 4.29Å; W190-L194 WeakPolarHBondContact O-CB 3.08Å; W190-L194 PolarHBondContact O-N 3.27Å
191	T	82.9	Confident	79	Confident	20 Å²	20	64 Å²	64	12%	0.123	33%	0.333	C	S	.	.	H	α-helix	trans	-65.9	-38.4	178.5	55.9	0	0	0	0	112.7	F187 L188 L194 A195 L342	F187-T191 PolarHBondContact O-N 3.47Å; F187-T191 PolarHBondContact O-OG1 3.11Å; L188-T191 WeakPolarHBondContact CA-OG1 3.38Å; L188-T191 PolarHBondContact O-N 3.42Å; L188-T191 PolarHBondContact O-OG1 2.98Å; L188-T191 VanDerWaalsContact O-OG1 3.05Å; T191-L194 PolarHBondContact O-N 3.38Å; T191-A195 WeakPolarHBondContact O-CB 3.42Å; T191-A195 PolarHBondContact O-N 3.39Å; T191-L342 HydrophobicContact CG2-CD2 4.28Å
192	S	85.4	Confident	79.4	Confident	2 Å²	2	61.4 Å²	61.4	1%	0.014	32%	0.32	C	S	.	.	H	α-helix	trans	-67.6	-38	176.6	-61.5	0	0	0	0	112.2	N49 L188 W190 L194 A195 F196	N49-S192 WeakPolarHBondContact OD1-CB 3.33Å; N49-S192 PolarHBondContact OD1-OG 3.34Å; L188-S192 PolarHBondContact O-N 3.47Å; L188-S192 PolarHBondContact O-OG 3.36Å; L188-S192 VanDerWaalsContact O-OG 3.12Å; W190-S192 PolarHBondContact O-N 3.35Å; S192-L194 VanDerWaalsContact C-N 3.35Å; S192-A195 PolarHBondContact O-N 3.38Å; S192-F196 PolarHBondContact O-N 2.93Å; S192-F196 VanDerWaalsContact O-N 3.12Å
193	S	87.8	Confident	80.1	Confident	32 Å²	32	59.2 Å²	59.2	22%	0.224	30%	0.304	C	S	.	.	H	α-helix	trans	-64.7	-41	174.7	-57.1	0	0	0	0	111.2	F48 G189 W190 F196 I197	F48-S193 WeakPolarHBondContact CD2-OG 3.35Å; G189-S193 PolarHBondContact O-N 3.5Å; G189-S193 PolarHBondContact O-OG 2.93Å; W190-S193 PolarHBondContact O-N 2.96Å; S193-F196 PolarHBondContact O-N 3.39Å; S193-I197 WeakPolarHBondContact O-CG1 3.22Å; S193-I197 PolarHBondContact O-N 2.98Å
194	L	89.4	Confident	81.5	Confident	35 Å²	35	59.9 Å²	59.9	18%	0.183	31%	0.307	C	S	.	.	H	α-helix	trans	-64.8	-43.3	175.7	-175.2	64.2	0	0	0	112.2	W190 T191 S192 F196 I197 F198 L342	W190-L194 HydrophobicContact CH2-CD2 4.26Å; W190-L194 HydrophobicContact CZ3-CD2 4.29Å; W190-L194 WeakPolarHBondContact O-CB 3.08Å; W190-L194 PolarHBondContact O-N 3.27Å; T191-L194 PolarHBondContact O-N 3.38Å; S192-L194 VanDerWaalsContact C-N 3.35Å; L194-F196 VanDerWaalsContact C-N 3.33Å; L194-F196 PolarHBondContact O-N 3.49Å; L194-I197 WeakPolarHBondContact O-CB 3.37Å; L194-I197 PolarHBondContact O-N 3.01Å; L194-I197 VanDerWaalsContact O-N 3.16Å; L194-F198 HydrophobicContact CD1-CE1 4.07Å; L194-F198 HydrophobicContact CD1-CE2 4.04Å; L194-F198 HydrophobicContact CD1-CZ 3.65Å; L194-F198 HydrophobicContact CD2-CE2 3.96Å; L194-F198 HydrophobicContact CD2-CZ 4.09Å; L194-F198 HydrophobicContact CG-CD2 4.28Å; L194-F198 HydrophobicContact CG-CE2 3.61Å; L194-F198 HydrophobicContact CG-CZ 3.75Å; L194-F198 PolarHBondContact O-N 3.49Å; L194-F198 VanDerWaalsContact O-N 3.11Å; L194-L342 HydrophobicContact CD2-CD1 4.02Å
195	A	88.6	Confident	83.1	Confident	0 Å²	0	51.9 Å²	51.9	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-57.7	-45.1	176	0	0	0	0	0	111.4	N52 T191 S192 I197 F198 M199	N52-A195 VanDerWaalsContact OD1-CB 3.31Å; N52-A195 WeakPolarHBondContact OD1-CB 3.4Å; T191-A195 WeakPolarHBondContact O-CB 3.42Å; T191-A195 PolarHBondContact O-N 3.39Å; S192-A195 PolarHBondContact O-N 3.38Å; A195-I197 VanDerWaalsContact C-N 3.34Å; A195-I197 PolarHBondContact O-N 3.05Å; A195-F198 PolarHBondContact O-N 3.4Å; A195-M199 WeakPolarHBondContact O-CG 3.38Å; A195-M199 PolarHBondContact O-N 3.4Å
196	F	90.2	Very high	84.7	Confident	33 Å²	33	48.6 Å²	48.6	15%	0.145	26%	0.256	C	S	.	.	H	α-helix	trans	-57	-44.4	174.9	170.2	-107.7	0	0	0	112.8	F48 M51 M55 S192 S193 L194 F198 M199 L200 L291 L295	F48-F196 HydrophobicContact CD1-CB 4.17Å; F48-F196 HydrophobicContact CD1-CD1 4.08Å; F48-F196 HydrophobicContact CD1-CG 4.07Å; F48-F196 AromaticContact CE1-CD1 3.67Å; F48-F196 HydrophobicContact CE1-CD1 3.67Å; F48-F196 HydrophobicContact CE1-CE1 4.01Å; F48-F196 HydrophobicContact CE1-CG 4.1Å; M51-F196 HydrophobicContact CE-CD2 3.27Å; M51-F196 HydrophobicContact CE-CE2 3.24Å; M51-F196 HydrophobicContact CE-CG 4.28Å; M51-F196 HydrophobicContact CE-CZ 4.23Å; M55-F196 HydrophobicContact CE-CD2 4.08Å; M55-F196 HydrophobicContact CE-CE2 4.19Å; M55-F196 HydrophobicContact SD-CD2 4.09Å; S192-F196 PolarHBondContact O-N 2.93Å; S192-F196 VanDerWaalsContact O-N 3.12Å; S193-F196 PolarHBondContact O-N 3.39Å; L194-F196 VanDerWaalsContact C-N 3.33Å; L194-F196 PolarHBondContact O-N 3.49Å; F196-F198 VanDerWaalsContact C-N 3.3Å; F196-F198 PolarHBondContact O-N 2.88Å; F196-M199 PolarHBondContact O-N 3.39Å; F196-L200 WeakPolarHBondContact O-CB 3.32Å; F196-L200 PolarHBondContact O-N 3.5Å; F196-L291 HydrophobicContact CE2-CD2 3.96Å; F196-L291 HydrophobicContact CE2-CG 4.23Å; F196-L291 HydrophobicContact CZ-CD2 3.96Å; F196-L295 HydrophobicContact CD2-CD1 4.39Å; F196-L295 HydrophobicContact CE2-CD1 3.68Å
197	I	93.1	Very high	86.8	Confident	96 Å²	96	47.3 Å²	47.3	49%	0.492	24%	0.235	S	C	.	.	H	α-helix	trans	-60.3	-41.6	178	-67.2	166.5	0	0	0	110.8	S193 L194 A195 L200 Y201	S193-I197 WeakPolarHBondContact O-CG1 3.22Å; S193-I197 PolarHBondContact O-N 2.98Å; L194-I197 WeakPolarHBondContact O-CB 3.37Å; L194-I197 PolarHBondContact O-N 3.01Å; L194-I197 VanDerWaalsContact O-N 3.16Å; A195-I197 VanDerWaalsContact C-N 3.34Å; A195-I197 PolarHBondContact O-N 3.05Å; I197-L200 PolarHBondContact O-N 3.19Å; I197-Y201 WeakPolarHBondContact O-CB 3.43Å; I197-Y201 PolarHBondContact O-N 3.17Å
198	F	93.6	Very high	88.6	Confident	35 Å²	35	41.9 Å²	41.9	15%	0.154	22%	0.216	C	C	.	.	H	α-helix	trans	-65.1	-37.9	176.4	-64.8	-30.6	0	0	0	112.9	L194 A195 F196 Y201 F202 A335 L338	L194-F198 HydrophobicContact CD1-CE1 4.07Å; L194-F198 HydrophobicContact CD1-CE2 4.04Å; L194-F198 HydrophobicContact CD1-CZ 3.65Å; L194-F198 HydrophobicContact CD2-CE2 3.96Å; L194-F198 HydrophobicContact CD2-CZ 4.09Å; L194-F198 HydrophobicContact CG-CD2 4.28Å; L194-F198 HydrophobicContact CG-CE2 3.61Å; L194-F198 HydrophobicContact CG-CZ 3.75Å; L194-F198 PolarHBondContact O-N 3.49Å; L194-F198 VanDerWaalsContact O-N 3.11Å; A195-F198 PolarHBondContact O-N 3.4Å; F196-F198 VanDerWaalsContact C-N 3.3Å; F196-F198 PolarHBondContact O-N 2.88Å; F198-Y201 PolarHBondContact O-N 3Å; F198-F202 WeakPolarHBondContact O-CB 3.47Å; F198-F202 PolarHBondContact O-N 2.83Å; F198-A335 HydrophobicContact CB-CB 4.07Å; F198-A335 HydrophobicContact CD1-CB 3.69Å; F198-A335 VanDerWaalsContact CD2-O 3.29Å; F198-A335 WeakPolarHBondContact CD2-O 3.35Å; F198-A335 HydrophobicContact CE1-CB 4.27Å; F198-A335 HydrophobicContact CG-CB 3.89Å; F198-L338 HydrophobicContact CE2-CB 4.13Å; F198-L338 HydrophobicContact CE2-CD2 3.6Å; F198-L338 HydrophobicContact CE2-CG 3.81Å; F198-L338 HydrophobicContact CZ-CD2 3.63Å; F198-L338 HydrophobicContact CZ-CG 4.35Å
199	M	92.3	Very high	90.2	Very high	9 Å²	9	40.3 Å²	40.3	4%	0.044	21%	0.207	C	C	.	.	H	α-helix	trans	-69.8	-37.8	176.2	-59.6	-52.3	-77.9	0	0	112.4	M55 I59 A195 F196 F202 T203	M55-M199 HydrophobicContact CB-CE 4.13Å; M55-M199 HydrophobicContact CB-CG 4.21Å; M55-M199 HydrophobicContact SD-CB 3.91Å; M55-M199 HydrophobicContact SD-CG 4.15Å; I59-M199 HydrophobicContact CB-CE 3.9Å; I59-M199 HydrophobicContact CD1-CE 3.95Å; I59-M199 HydrophobicContact CG2-CE 3.25Å; A195-M199 WeakPolarHBondContact O-CG 3.38Å; A195-M199 PolarHBondContact O-N 3.4Å; F196-M199 PolarHBondContact O-N 3.39Å; M199-F202 PolarHBondContact O-N 3.24Å; M199-T203 PolarHBondContact O-N 2.9Å; M199-T203 PolarHBondContact O-OG1 2.92Å
200	L	94.9	Very high	91.4	Very high	74 Å²	74	40.6 Å²	40.6	39%	0.387	20%	0.2	S	C	.	.	H	α-helix	trans	-63.1	-45.6	172	-179.5	64.1	0	0	0	110.6	F196 I197 F202 T203 V204 L295	F196-L200 WeakPolarHBondContact O-CB 3.32Å; F196-L200 PolarHBondContact O-N 3.5Å; I197-L200 PolarHBondContact O-N 3.19Å; L200-F202 PolarHBondContact O-N 3.17Å; L200-T203 WeakPolarHBondContact O-CB 3.47Å; L200-T203 PolarHBondContact O-N 3.05Å; L200-T203 VanDerWaalsContact O-N 3.15Å; L200-V204 WeakPolarHBondContact O-CG2 3.34Å; L200-V204 PolarHBondContact O-N 2.68Å; L200-L295 HydrophobicContact CD1-CD2 3.8Å
201	Y	95.7	Very high	92	Very high	86 Å²	86	41.2 Å²	41.2	34%	0.337	20%	0.203	S	C	.	.	H	α-helix	trans	-59.8	-45.6	176.6	177.1	-119	0	0	0	112.3	I197 F198 T203 V204 V205 T331 V332 A335	I197-Y201 WeakPolarHBondContact O-CB 3.43Å; I197-Y201 PolarHBondContact O-N 3.17Å; F198-Y201 PolarHBondContact O-N 3Å; Y201-T203 VanDerWaalsContact C-N 3.31Å; Y201-T203 PolarHBondContact O-N 2.93Å; Y201-V204 PolarHBondContact O-N 3.42Å; Y201-V205 HydrophobicContact CD2-CG2 4.22Å; Y201-V205 HydrophobicContact CE1-CG2 4.35Å; Y201-V205 HydrophobicContact CE2-CG2 3.71Å; Y201-V205 WeakPolarHBondContact O-CG2 3.29Å; Y201-V205 PolarHBondContact O-N 3.47Å; Y201-T331 PolarHBondContact OH-OG1 3.42Å; Y201-V332 HydrophobicContact CD1-CG2 3.75Å; Y201-V332 HydrophobicContact CE1-CB 4.25Å; Y201-V332 HydrophobicContact CE1-CG2 3.33Å; Y201-A335 HydrophobicContact CD1-CB 4.22Å
202	F	95.1	Very high	92.1	Very high	1 Å²	1	42.5 Å²	42.5	0%	0.004	21%	0.212	C	C	.	.	H	α-helix	trans	-53.5	-48.6	171.7	164	-99.7	0	0	0	111.8	I59 L60 F198 M199 L200 V204 V205 V206 L315 L316 V332 I336	I59-F202 HydrophobicContact CD1-CD1 3.99Å; I59-F202 HydrophobicContact CD1-CE1 3.86Å; I59-F202 HydrophobicContact CG1-CE1 3.95Å; I59-F202 HydrophobicContact CG2-CD1 4.45Å; I59-F202 HydrophobicContact CG2-CE1 3.97Å; I59-F202 HydrophobicContact CG2-CZ 4.47Å; L60-F202 HydrophobicContact CD2-CE1 4.39Å; L60-F202 HydrophobicContact CD2-CE2 3.7Å; L60-F202 HydrophobicContact CD2-CZ 3.58Å; F198-F202 WeakPolarHBondContact O-CB 3.47Å; F198-F202 PolarHBondContact O-N 2.83Å; M199-F202 PolarHBondContact O-N 3.24Å; L200-F202 PolarHBondContact O-N 3.17Å; F202-V204 PolarHBondContact O-N 3.08Å; F202-V205 PolarHBondContact O-N 3.49Å; F202-V206 HydrophobicContact CD1-CG2 4.5Å; F202-V206 HydrophobicContact CD2-CG2 4.11Å; F202-V206 HydrophobicContact CE1-CG2 4.16Å; F202-V206 HydrophobicContact CE2-CG2 3.76Å; F202-V206 HydrophobicContact CZ-CG2 3.8Å; F202-V206 WeakPolarHBondContact O-CG2 3.12Å; F202-V206 PolarHBondContact O-N 3.49Å; F202-L315 HydrophobicContact CE2-CD2 4.37Å; F202-L315 HydrophobicContact CZ-CD2 3.8Å; F202-L316 HydrophobicContact CE2-CD1 4.34Å; F202-L316 HydrophobicContact CE2-CG 4.38Å; F202-V332 HydrophobicContact CB-CG1 4.05Å; F202-V332 HydrophobicContact CD2-CG1 3.6Å; F202-V332 HydrophobicContact CG-CG1 4.31Å; F202-I336 HydrophobicContact CB-CD1 3.99Å; F202-I336 HydrophobicContact CD2-CD1 3.37Å; F202-I336 HydrophobicContact CE2-CD1 3.96Å; F202-I336 HydrophobicContact CG-CD1 3.79Å
203	T	95.7	Very high	92	Very high	7 Å²	7	42.8 Å²	42.8	4%	0.043	21%	0.214	C	C	.	.	H	α-helix	trans	-60	-45.8	-179.6	-55.4	0	0	0	0	111.2	M199 L200 Y201 V205 V206 V207 L295 V298 S299	M199-T203 PolarHBondContact O-N 2.9Å; M199-T203 PolarHBondContact O-OG1 2.92Å; L200-T203 WeakPolarHBondContact O-CB 3.47Å; L200-T203 PolarHBondContact O-N 3.05Å; L200-T203 VanDerWaalsContact O-N 3.15Å; Y201-T203 VanDerWaalsContact C-N 3.31Å; Y201-T203 PolarHBondContact O-N 2.93Å; T203-V205 PolarHBondContact O-N 2.91Å; T203-V206 PolarHBondContact O-N 3.26Å; T203-V207 WeakPolarHBondContact O-CG2 3.49Å; T203-V207 PolarHBondContact O-N 3.04Å; T203-V207 VanDerWaalsContact O-N 3.09Å; T203-L295 HydrophobicContact CG2-CD2 3.93Å; T203-V298 HydrophobicContact CG2-CB 4.08Å; T203-V298 HydrophobicContact CG2-CG1 3.67Å; T203-S299 WeakPolarHBondContact CG2-OG 3.46Å; T203-S299 PolarHBondContact OG1-OG 2.93Å
204	V	96.2	Very high	91.7	Very high	78 Å²	78	45.1 Å²	45.1	47%	0.473	23%	0.228	S	C	.	.	H	α-helix	trans	-59.7	-45.1	177.1	171.8	0	0	0	0	111.2	L200 Y201 F202 V207 V208	L200-V204 WeakPolarHBondContact O-CG2 3.34Å; L200-V204 PolarHBondContact O-N 2.68Å; Y201-V204 PolarHBondContact O-N 3.42Å; F202-V204 PolarHBondContact O-N 3.08Å; V204-V207 PolarHBondContact O-N 3.45Å; V204-V208 WeakPolarHBondContact O-CG2 3.41Å; V204-V208 PolarHBondContact O-N 3.06Å
205	V	95.2	Very high	91.1	Very high	11 Å²	11	45.7 Å²	45.7	7%	0.067	23%	0.234	C	C	.	.	H	α-helix	trans	-66	-40	179.2	172.7	0	0	0	0	111.7	Y201 F202 T203 V207 V208 K209 M328 V332	Y201-V205 HydrophobicContact CD2-CG2 4.22Å; Y201-V205 HydrophobicContact CE1-CG2 4.35Å; Y201-V205 HydrophobicContact CE2-CG2 3.71Å; Y201-V205 WeakPolarHBondContact O-CG2 3.29Å; Y201-V205 PolarHBondContact O-N 3.47Å; F202-V205 PolarHBondContact O-N 3.49Å; T203-V205 PolarHBondContact O-N 2.91Å; V205-V207 VanDerWaalsContact C-N 3.29Å; V205-V207 PolarHBondContact O-N 3.26Å; V205-V208 PolarHBondContact O-N 2.95Å; V205-K209 HydrophobicContact CG1-CG 3.89Å; V205-K209 WeakPolarHBondContact O-CB 3.33Å; V205-K209 VanDerWaalsContact O-CG 3.24Å; V205-K209 WeakPolarHBondContact O-CG 3.33Å; V205-K209 PolarHBondContact O-N 3.13Å; V205-M328 HydrophobicContact CG1-CB 4.15Å; V205-V332 HydrophobicContact CB-CG2 3.57Å; V205-V332 HydrophobicContact CG1-CG2 3.75Å; V205-V332 HydrophobicContact CG2-CG2 3.44Å; V205-V332 VanDerWaalsContact CG2-CG2 3.44Å
206	V	95.1	Very high	90.5	Very high	2 Å²	2	49.3 Å²	49.3	1%	0.012	26%	0.258	C	S	.	.	H	α-helix	trans	-58	-42.9	174.7	169.9	0	0	0	0	111.2	F202 T203 K209 K210 F302 L315 Y319	F202-V206 HydrophobicContact CD1-CG2 4.5Å; F202-V206 HydrophobicContact CD2-CG2 4.11Å; F202-V206 HydrophobicContact CE1-CG2 4.16Å; F202-V206 HydrophobicContact CE2-CG2 3.76Å; F202-V206 HydrophobicContact CZ-CG2 3.8Å; F202-V206 WeakPolarHBondContact O-CG2 3.12Å; F202-V206 PolarHBondContact O-N 3.49Å; T203-V206 PolarHBondContact O-N 3.26Å; V206-K209 PolarHBondContact O-N 3Å; V206-K210 PolarHBondContact O-N 3.39Å; V206-F302 HydrophobicContact CG1-CB 3.87Å; V206-L315 HydrophobicContact CG1-CD2 4.22Å; V206-L315 HydrophobicContact CG2-CD2 3.87Å; V206-Y319 HydrophobicContact CG2-CE2 4.08Å
207	V	95.9	Very high	90	Very high	40 Å²	40	49.3 Å²	49.3	24%	0.242	26%	0.259	C	S	.	.	H	α-helix	trans	-62.4	-46.2	175.6	176	0	0	0	0	111.4	T203 V204 V205 K209 K210 W211 V298 F302	T203-V207 WeakPolarHBondContact O-CG2 3.49Å; T203-V207 PolarHBondContact O-N 3.04Å; T203-V207 VanDerWaalsContact O-N 3.09Å; V204-V207 PolarHBondContact O-N 3.45Å; V205-V207 VanDerWaalsContact C-N 3.29Å; V205-V207 PolarHBondContact O-N 3.26Å; V207-K209 VanDerWaalsContact C-N 3.34Å; V207-K209 PolarHBondContact O-N 3.44Å; V207-K210 PolarHBondContact O-N 2.99Å; V207-W211 VanDerWaalsContact O-CD1 3.24Å; V207-V298 HydrophobicContact CG2-CG1 3.64Å; V207-F302 HydrophobicContact CB-CD1 4.46Å; V207-F302 HydrophobicContact CB-CG 4.34Å; V207-F302 HydrophobicContact CG1-CD1 4.23Å; V207-F302 HydrophobicContact CG1-CE1 4.11Å; V207-F302 HydrophobicContact CG1-CG 4.49Å; V207-F302 HydrophobicContact CG1-CZ 4.25Å; V207-F302 HydrophobicContact CG2-CB 4.27Å; V207-F302 HydrophobicContact CG2-CD1 4.4Å; V207-F302 HydrophobicContact CG2-CD2 3.66Å; V207-F302 HydrophobicContact CG2-CE2 4.05Å; V207-F302 HydrophobicContact CG2-CG 3.85Å
208	V	94.1	Very high	88.8	Confident	59 Å²	59	48 Å²	48	36%	0.358	26%	0.257	S	S	.	.	H	α-helix	trans	-64.2	-39.9	178.9	171.9	0	0	0	0	111.3	V204 V205 K210 W211 S212 M328	V204-V208 WeakPolarHBondContact O-CG2 3.41Å; V204-V208 PolarHBondContact O-N 3.06Å; V205-V208 PolarHBondContact O-N 2.95Å; V208-K210 VanDerWaalsContact C-N 3.34Å; V208-K210 PolarHBondContact O-N 3.48Å; V208-W211 PolarHBondContact O-N 2.79Å; V208-S212 PolarHBondContact O-N 3.09Å; V208-S212 PolarHBondContact O-OG 3.01Å; V208-M328 HydrophobicContact CG1-SD 4.16Å
209	K	90.8	Very high	87.2	Confident	6 Å²	6	52.8 Å²	52.8	3%	0.026	28%	0.275	C	S	.	.	H	α-helix	trans	-70.2	-28.1	-176.9	-68.7	-62.9	172.6	-159.9	0	113.6	V205 V206 V207 W211 S212 I213 Y319 D326 V329	V205-K209 HydrophobicContact CG1-CG 3.89Å; V205-K209 WeakPolarHBondContact O-CB 3.33Å; V205-K209 VanDerWaalsContact O-CG 3.24Å; V205-K209 WeakPolarHBondContact O-CG 3.33Å; V205-K209 PolarHBondContact O-N 3.13Å; V206-K209 PolarHBondContact O-N 3Å; V207-K209 VanDerWaalsContact C-N 3.34Å; V207-K209 PolarHBondContact O-N 3.44Å; K209-W211 PolarHBondContact O-N 3.43Å; K209-W211 VanDerWaalsContact O-N 3.17Å; K209-S212 PolarHBondContact O-N 3.46Å; K209-I213 HydrophobicContact CB-CD1 4.45Å; K209-I213 PolarHBondContact O-N 3.46Å; K209-Y319 HydrophobicContact CB-CD1 4.33Å; K209-Y319 HydrophobicContact CB-CE1 3.47Å; K209-Y319 VanDerWaalsContact CB-CE1 3.47Å; K209-Y319 HydrophobicContact CG-CD1 4.43Å; K209-Y319 HydrophobicContact CG-CE1 3.97Å; K209-D326 IonicContact NZ-OD1 3.59Å; K209-D326 PolarHBondContact NZ-OD1 2.9Å; K209-D326 IonicContact NZ-OD2 2.65Å; K209-D326 PolarHBondContact NZ-OD2 3.22Å; K209-V329 HydrophobicContact CD-CG2 4.39Å
210	K	90.5	Very high	85.1	Confident	36 Å²	36	59.5 Å²	59.5	16%	0.157	31%	0.311	C	S	.	.	H	α-helix	trans	-52.8	-36.1	170.8	171.6	63.8	-160.9	97.2	0	113.2	V206 V207 V208 F302 L305 T306	V206-K210 PolarHBondContact O-N 3.39Å; V207-K210 PolarHBondContact O-N 2.99Å; V208-K210 VanDerWaalsContact C-N 3.34Å; V208-K210 PolarHBondContact O-N 3.48Å; K210-F302 HydrophobicContact CB-CD1 3.91Å; K210-F302 HydrophobicContact CG-CD1 3.95Å; K210-L305 HydrophobicContact CD-CB 3.61Å; K210-L305 WeakPolarHBondContact CD-O 3.33Å; K210-L305 WeakPolarHBondContact CE-O 3.43Å; K210-L305 PolarHBondContact NZ-O 3.1Å; K210-T306 WeakPolarHBondContact CA-OG1 3.42Å
211	W	89.2	Confident	82.5	Confident	203 Å²	203	59.5 Å²	59.5	77%	0.769	31%	0.31	S	S	*	.	H	α-helix	trans	-88.2	-15.5	179.7	-58.1	105.1	0	0	0	113	V207 V208 K209	V207-W211 VanDerWaalsContact O-CD1 3.24Å; V208-W211 PolarHBondContact O-N 2.79Å; K209-W211 PolarHBondContact O-N 3.43Å; K209-W211 VanDerWaalsContact O-N 3.17Å
212	S	85.8	Confident	80	Confident	47 Å²	47	62.1 Å²	62.1	33%	0.329	34%	0.335	S	S	.	.	H	α-helix	trans	-92.2	-24.6	-179.3	-55.9	0	0	0	0	113.6	V208 K209 R323	V208-S212 PolarHBondContact O-N 3.09Å; V208-S212 PolarHBondContact O-OG 3.01Å; K209-S212 PolarHBondContact O-N 3.46Å; S212-R323 PolarHBondContact O-NH2 3.11Å
213	I	83.7	Confident	77.1	Confident	8 Å²	8	66.5 Å²	66.5	4%	0.041	36%	0.362	C	S	.	.	S	Bend	trans	-101.8	117.6	-177.9	-63	172.6	0	0	0	108.5	K209 L217 T306 F307 Y319 R323	K209-I213 HydrophobicContact CB-CD1 4.45Å; K209-I213 PolarHBondContact O-N 3.46Å; I213-L217 HydrophobicContact CG2-CD2 3.92Å; I213-T306 HydrophobicContact CB-CG2 4.2Å; I213-T306 HydrophobicContact CD1-CG2 3.75Å; I213-T306 HydrophobicContact CG2-CG2 4.38Å; I213-F307 HydrophobicContact CD1-CE1 4.48Å; I213-F307 HydrophobicContact CD1-CZ 4.45Å; I213-Y319 HydrophobicContact CD1-CD1 3.82Å; I213-Y319 HydrophobicContact CD1-CE1 3.7Å; I213-R323 HydrophobicContact CD1-CG 4.39Å; I213-R323 HydrophobicContact CG1-CG 4.38Å
214	P	80.6	Confident	74.8	Confident	82 Å²	82	74.5 Å²	74.5	53%	0.532	40%	0.404	S	S	.	.			trans	-72.5	154.7	178.1	31.2	-34.4	0	0	0	111.2
215	C	78	Confident	71.9	Confident	46 Å²	46	74.4 Å²	74.4	31%	0.311	41%	0.406	S	S	.	.	S	Bend	trans	-119.4	130.4	166.1	-159.3	0	0	0	0	107.6	C238 Y308	C215-C238 VanDerWaalsContact C-SG 3.51Å; C215-C238 HydrophobicContact CB-CB 3.89Å; C215-C238 WeakPolarHBondContact CB-SG 3.5Å; C215-C238 VanDerWaalsContact SG-CA 3.6Å; C215-C238 WeakPolarHBondContact SG-CB 3.28Å; C215-C238 CovalentContact SG-SG 2.03Å; C215-C238 PolarHBondContact SG-SG 3.03Å; C215-Y308 HydrophobicContact CB-CE2 4.07Å; C215-Y308 VanDerWaalsContact SG-CE2 3.52Å
216	P	75.4	Confident	69	Low	77 Å²	77	80.8 Å²	80.8	50%	0.5	44%	0.44	S	S	.	.	S	Bend	cis	-66.4	149.5	6.2	27.8	-35.1	0	0	0	113.6
217	L	79.6	Confident	66.4	Low	32 Å²	32	89.5 Å²	89.5	17%	0.168	48%	0.479	C	S	.	.			trans	-62	137	-178.1	-71.7	154.8	0	0	0	109.4	I213 Y219 F307 H310 Y322	I213-L217 HydrophobicContact CG2-CD2 3.92Å; L217-Y219 PolarHBondContact O-N 3.29Å; L217-F307 HydrophobicContact CD1-CD1 4.46Å; L217-F307 HydrophobicContact CD2-CD1 3.89Å; L217-F307 HydrophobicContact CD2-CE1 4.31Å; L217-H310 HydrophobicContact CD1-CB 4.2Å; L217-Y322 HydrophobicContact CB-CD1 4.45Å; L217-Y322 HydrophobicContact CB-CE1 3.86Å; L217-Y322 HydrophobicContact CD1-CE1 4.38Å; L217-Y322 HydrophobicContact CD1-CE2 4.36Å; L217-Y322 HydrophobicContact CD2-CD1 4.17Å; L217-Y322 HydrophobicContact CD2-CD2 4.28Å; L217-Y322 HydrophobicContact CD2-CE1 4.05Å; L217-Y322 HydrophobicContact CD2-CE2 4.17Å; L217-Y322 HydrophobicContact CD2-CG 4.29Å; L217-Y322 HydrophobicContact CG-CE1 4.31Å
218	P	68.5	Low	63.8	Low	68 Å²	68	93.2 Å²	93.2	44%	0.442	50%	0.501	S	S	.	.			trans	-62.9	112	177.5	25.6	-31.7	0	0	0	108.5
219	Y	59.7	Low	61.1	Low	136 Å²	136	100 Å²	100	53%	0.533	53%	0.526	S	S	.	.			trans	-66.6	143.8	166.4	68.5	-81.5	0	0	0	107.8	L217 M221	L217-Y219 PolarHBondContact O-N 3.29Å; Y219-M221 HydrophobicContact CD2-CB 3.74Å; Y219-M221 HydrophobicContact CD2-CG 4.3Å; Y219-M221 HydrophobicContact CE2-CB 3.28Å; Y219-M221 HydrophobicContact CE2-CE 4.38Å; Y219-M221 HydrophobicContact CE2-CG 3.37Å; Y219-M221 HydrophobicContact CE2-SD 3.92Å; Y219-M221 VanDerWaalsContact CZ-SD 3.55Å; Y219-M221 PolarHBondContact O-N 3.39Å; Y219-M221 WeakPolarHBondContact OH-CE 3.38Å; Y219-M221 PolarHBondContact OH-SD 2.99Å
220	N	48.3	Very low	59.1	Low	150 Å²	150	106.1 Å²	106.1	80%	0.802	56%	0.563	S	S	*	*			trans	-62.3	85.3	170.7	-82.5	-19.5	0	0	0	108.9	T222	N220-T222 PolarHBondContact O-N 3.12Å
221	M	40.4	Very low	56.6	Low	74 Å²	74	109 Å²	109	37%	0.365	59%	0.588	S	S	.	*			trans	-83.2	83.9	172.9	-163.4	178.4	-157.3	0	0	108.1	Y219 T223 F227	Y219-M221 HydrophobicContact CD2-CB 3.74Å; Y219-M221 HydrophobicContact CD2-CG 4.3Å; Y219-M221 HydrophobicContact CE2-CB 3.28Å; Y219-M221 HydrophobicContact CE2-CE 4.38Å; Y219-M221 HydrophobicContact CE2-CG 3.37Å; Y219-M221 HydrophobicContact CE2-SD 3.92Å; Y219-M221 VanDerWaalsContact CZ-SD 3.55Å; Y219-M221 PolarHBondContact O-N 3.39Å; Y219-M221 WeakPolarHBondContact OH-CE 3.38Å; Y219-M221 PolarHBondContact OH-SD 2.99Å; M221-T223 WeakPolarHBondContact CE-O 3.36Å; M221-T223 WeakPolarHBondContact CG-O 3.41Å; M221-T223 PolarHBondContact O-N 3.36Å; M221-F227 HydrophobicContact SD-CE2 4.33Å
222	T	41.8	Very low	54.4	Low	141 Å²	141	107.5 Å²	107.5	87%	0.865	60%	0.595	S	S	*	*			trans	-78.7	9.3	156.6	33.9	0	0	0	0	112.5	N220	N220-T222 PolarHBondContact O-N 3.12Å
223	T	35.7	Very low	52.6	Low	93 Å²	93	109.9 Å²	109.9	57%	0.571	61%	0.612	S	S	*	*			trans	-113.1	92.3	174.3	41.8	0	0	0	0	111.4	M221 S225	M221-T223 WeakPolarHBondContact CE-O 3.36Å; M221-T223 WeakPolarHBondContact CG-O 3.41Å; M221-T223 PolarHBondContact O-N 3.36Å; T223-S225 PolarHBondContact O-N 3.35Å; T223-S225 VanDerWaalsContact O-N 3.08Å
224	L	45.6	Very low	51	Low	175 Å²	175	112.1 Å²	112.1	92%	0.916	63%	0.629	S	S	*	*			trans	-39.6	109.8	154.2	179.5	76.6	0	0	0	110.8
225	S	36.3	Very low	49.4	Very low	76 Å²	76	115.5 Å²	115.5	53%	0.531	64%	0.642	S	S	.	*			trans	-178.2	117.6	143	41	0	0	0	0	112.2	T223	T223-S225 PolarHBondContact O-N 3.35Å; T223-S225 VanDerWaalsContact O-N 3.08Å
226	N	33.7	Very low	48.5	Very low	146 Å²	146	117.5 Å²	117.5	78%	0.781	66%	0.657	S	S	*	*			trans	55.2	85.7	143.6	-57.1	-11.5	0	0	0	118	T228	N226-T228 PolarHBondContact O-N 3.34Å
227	F	40.9	Very low	48.3	Very low	185 Å²	185	118.5 Å²	118.5	81%	0.811	66%	0.655	S	S	*	*			trans	-69.6	70.4	157.8	-90	-88.1	0	0	0	111.4	M221	M221-F227 HydrophobicContact SD-CE2 4.33Å
228	T	42.3	Very low	48.3	Very low	117 Å²	117	118.4 Å²	118.4	72%	0.718	66%	0.656	S	S	*	*			trans	-141.6	85.9	154	52.6	0	0	0	0	108.2	N226	N226-T228 PolarHBondContact O-N 3.34Å
229	K	36.2	Very low	49	Very low	201 Å²	201	118.4 Å²	118.4	87%	0.874	66%	0.655	S	S	*	*			trans	-178.9	118.4	137.8	-101.1	164.9	-176.1	177.3	0	111
230	V	49.5	Very low	50.4	Low	135 Å²	135	115 Å²	115	82%	0.818	65%	0.65	S	S	*	*			trans	-43.1	129.9	156.7	172.3	0	0	0	0	110.1
231	S	38.4	Very low	52.3	Low	96 Å²	96	112.8 Å²	112.8	67%	0.671	63%	0.633	S	S	*	*			trans	-147.2	128.8	159.2	-54.3	0	0	0	0	108.1	S233	S231-S233 VanDerWaalsContact C-N 3.32Å; S231-S233 PolarHBondContact O-N 3.04Å
232	N	42.2	Very low	54.6	Low	172 Å²	172	114.7 Å²	114.7	92%	0.92	64%	0.644	S	S	*	*	S	Bend	trans	-65.9	73.4	-171.7	-74.8	-26.2	0	0	0	113.9
233	S	47.9	Very low	56.9	Low	97 Å²	97	114.4 Å²	114.4	68%	0.678	63%	0.631	S	S	*	*			trans	-148.5	95.9	168.2	58	0	0	0	0	109.9	S231	S231-S233 VanDerWaalsContact C-N 3.32Å; S231-S233 PolarHBondContact O-N 3.04Å
234	S	49.3	Very low	59.5	Low	56 Å²	56	112 Å²	112	39%	0.392	61%	0.614	S	S	.	*			trans	174.5	0.4	156.6	37.9	0	0	0	0	116.7	S236 E237	S234-S236 PolarHBondContact O-N 3.36Å; S234-E237 PolarHBondContact O-N 3.05Å
235	D	48.6	Very low	61.3	Low	152 Å²	152	110.5 Å²	110.5	81%	0.813	61%	0.606	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.3	-20.6	173.8	-80.6	-17.1	0	0	0	112.9	T239	D235-T239 WeakPolarHBondContact O-CG2 3.33Å; D235-T239 PolarHBondContact O-OG1 2.87Å
236	S	58.9	Low	63.6	Low	89 Å²	89	109.6 Å²	109.6	62%	0.622	60%	0.6	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.9	-13.2	-178.2	59.5	0	0	0	0	115.3	S234 T239	S234-S236 PolarHBondContact O-N 3.36Å; S236-T239 PolarHBondContact O-OG1 3.3Å
237	E	70.3	Confident	65.8	Low	98 Å²	98	107.8 Å²	107.8	46%	0.458	59%	0.589	S	S	.	*	T	Hydrogen-bonded Turn	trans	-89.4	-34.8	-176.6	-72.8	-171.7	164.9	0	0	113	S234 Y308	S234-E237 PolarHBondContact O-N 3.05Å; E237-Y308 VanDerWaalsContact O-CB 3.3Å; E237-Y308 WeakPolarHBondContact O-CB 3.17Å
238	C	79.9	Confident	67.9	Low	30 Å²	30	104.8 Å²	104.8	20%	0.203	58%	0.576	C	S	.	*	S	Bend	trans	-96.3	17	180	-61.2	0	0	0	0	113.2	C215 Y308	C215-C238 VanDerWaalsContact C-SG 3.51Å; C215-C238 HydrophobicContact CB-CB 3.89Å; C215-C238 WeakPolarHBondContact CB-SG 3.5Å; C215-C238 VanDerWaalsContact SG-CA 3.6Å; C215-C238 WeakPolarHBondContact SG-CB 3.28Å; C215-C238 CovalentContact SG-SG 2.03Å; C215-C238 PolarHBondContact SG-SG 3.03Å; C238-Y308 VanDerWaalsContact C-CE1 3.46Å; C238-Y308 HydrophobicContact CB-CE2 4.34Å; C238-Y308 WeakPolarHBondContact O-CE1 3.2Å; C238-Y308 VanDerWaalsContact O-CZ 3.22Å; C238-Y308 PolarHBondContact O-OH 3.47Å
239	T	84	Confident	70	Confident	68 Å²	68	100.1 Å²	100.1	42%	0.417	55%	0.548	S	S	.	.	S	Bend	trans	-98.3	128.1	178.2	39.5	0	0	0	0	111.3	D235 S236 K241	D235-T239 WeakPolarHBondContact O-CG2 3.33Å; D235-T239 PolarHBondContact O-OG1 2.87Å; S236-T239 PolarHBondContact O-OG1 3.3Å; T239-K241 PolarHBondContact O-N 3.21Å
240	P	87.3	Confident	72.5	Confident	65 Å²	65	91.5 Å²	91.5	42%	0.422	51%	0.514	S	S	.	.	P	Polyproline II helix	trans	-67.8	127	177.6	27.8	-32.4	0	0	0	109.6	I71 Y304 L305 Y308	I71-P240 HydrophobicContact CD1-CB 3.75Å; P240-Y304 HydrophobicContact CB-CE1 4.4Å; P240-L305 HydrophobicContact CB-CD2 4.08Å; P240-Y308 HydrophobicContact CB-CE1 4.46Å
241	K	89.1	Confident	74.4	Confident	103 Å²	103	86 Å²	86	45%	0.448	48%	0.479	S	S	.	.	P	Polyproline II helix	trans	-88.1	121.7	175.1	-66.5	-179.7	179.4	177.9	0	108.7	G70 I71 T239 I244 Y304	G70-K241 CarbonylContact C-O 3.55Å; G70-K241 WeakPolarHBondContact CA-O 3.26Å; I71-K241 PolarHBondContact N-O 2.98Å; T239-K241 PolarHBondContact O-N 3.21Å; K241-I244 HydrophobicContact CB-CD1 3.62Å; K241-I244 HydrophobicContact CB-CG1 3.77Å; K241-I244 HydrophobicContact CD-CD1 3.33Å; K241-I244 HydrophobicContact CD-CG1 3.96Å; K241-I244 HydrophobicContact CG-CD1 4.08Å; K241-I244 HydrophobicContact CG-CG1 4.46Å; K241-Y304 PolarHBondContact N-OH 2.6Å
242	L	89.3	Confident	77	Confident	113 Å²	113	81.4 Å²	81.4	59%	0.592	45%	0.447	S	S	*	.	S	Bend	trans	-72.9	-40.9	-177.9	-66.1	175.6	0	0	0	111.9	G70 I71 V72	G70-L242 CarbonylContact C-O 3.52Å; I71-L242 PolarHBondContact N-O 3.34Å; V72-L242 WeakPolarHBondContact CB-O 3.38Å; V72-L242 HydrophobicContact CG2-CB 4.04Å; V72-L242 HydrophobicContact CG2-CD2 4.1Å; V72-L242 PolarHBondContact N-O 3.3Å
243	F	90.6	Very high	79.4	Confident	136 Å²	136	75.2 Å²	75.2	60%	0.596	41%	0.413	S	S	*	.			trans	-145.7	132.4	-179.8	-171	-97.7	0	0	0	110.7	L245	F243-L245 HydrophobicContact CE1-CB 4.27Å
244	I	88.6	Confident	81.6	Confident	43 Å²	43	70.6 Å²	70.6	22%	0.221	38%	0.381	C	S	.	.			trans	-139.3	131.8	175.6	-50.8	173.8	0	0	0	107.7	T69 K241	T69-I244 CarbonylContact C-O 3.56Å; T69-I244 WeakPolarHBondContact CA-O 3.26Å; T69-I244 PolarHBondContact O-N 3.47Å; K241-I244 HydrophobicContact CB-CD1 3.62Å; K241-I244 HydrophobicContact CB-CG1 3.77Å; K241-I244 HydrophobicContact CD-CD1 3.33Å; K241-I244 HydrophobicContact CD-CG1 3.96Å; K241-I244 HydrophobicContact CG-CD1 4.08Å; K241-I244 HydrophobicContact CG-CG1 4.46Å
245	L	84.8	Confident	83.8	Confident	143 Å²	143	68 Å²	68	75%	0.749	36%	0.363	S	S	*	.			trans	-115.7	114.9	167.2	-163.6	72.9	0	0	0	107.9	F243	F243-L245 HydrophobicContact CE1-CB 4.27Å
246	S	82.8	Confident	86	Confident	57 Å²	57	60.8 Å²	60.8	40%	0.399	32%	0.324	S	S	.	.			trans	-141.4	164.1	-177.7	-178	0	0	0	0	109.2	K248 S249	S246-K248 PolarHBondContact O-N 3.14Å; S246-S249 PolarHBondContact N-OG 3.37Å; S246-S249 WeakPolarHBondContact O-CB 3.42Å; S246-S249 PolarHBondContact O-N 3.17Å; S246-S249 PolarHBondContact O-OG 3.05Å
247	I	81.6	Confident	87.7	Confident	108 Å²	108	56.5 Å²	56.5	55%	0.554	29%	0.294	S	S	*	.	G	3₁₀ helix	trans	-54.2	-32.2	173.3	-62.7	169.7	0	0	0	110.9	S249 A250 V448	I247-S249 VanDerWaalsContact C-N 3.27Å; I247-S249 PolarHBondContact O-N 3.44Å; I247-A250 VanDerWaalsContact O-CB 3.27Å; I247-A250 WeakPolarHBondContact O-CB 3.36Å; I247-A250 PolarHBondContact O-N 3.37Å; I247-V448 HydrophobicContact CG2-CG1 3.9Å
248	K	83.7	Confident	88.9	Confident	122 Å²	122	52.5 Å²	52.5	53%	0.53	28%	0.276	S	S	.	.	G	3₁₀ helix	trans	-63.5	-27.7	175.2	-63	-178.4	-177.3	178.8	0	113.6	S246 A250 Y251	S246-K248 PolarHBondContact O-N 3.14Å; K248-A250 PolarHBondContact O-N 3.39Å; K248-Y251 PolarHBondContact O-N 3.37Å
249	S	87.1	Confident	89.7	Confident	19 Å²	19	51.1 Å²	51.1	13%	0.133	27%	0.266	C	S	.	.	G	3₁₀ helix	trans	-69.3	-16.3	178.4	71.9	0	0	0	0	112.7	S68 S246 I247 Y251 A252	S68-S249 WeakPolarHBondContact O-CB 3.49Å; S246-S249 PolarHBondContact N-OG 3.37Å; S246-S249 WeakPolarHBondContact O-CB 3.42Å; S246-S249 PolarHBondContact O-N 3.17Å; S246-S249 PolarHBondContact O-OG 3.05Å; I247-S249 VanDerWaalsContact C-N 3.27Å; I247-S249 PolarHBondContact O-N 3.44Å; S249-Y251 PolarHBondContact O-N 3.41Å; S249-A252 VanDerWaalsContact O-CB 3.27Å; S249-A252 WeakPolarHBondContact O-CB 3.43Å; S249-A252 PolarHBondContact O-N 2.95Å
250	A	87.9	Confident	90.2	Very high	19 Å²	19	47.9 Å²	47.9	16%	0.157	25%	0.246	C	C	.	.	G	3₁₀ helix	trans	-62.2	-23.5	173.8	0	0	0	0	0	113.3	I247 K248 P254 V448	I247-A250 VanDerWaalsContact O-CB 3.27Å; I247-A250 WeakPolarHBondContact O-CB 3.36Å; I247-A250 PolarHBondContact O-N 3.37Å; K248-A250 PolarHBondContact O-N 3.39Å; A250-P254 WeakPolarHBondContact O-CD 3.42Å; A250-P254 WeakPolarHBondContact O-CG 3.29Å; A250-V448 HydrophobicContact CB-CB 3.78Å; A250-V448 HydrophobicContact CB-CG1 3.38Å; A250-V448 HydrophobicContact CB-CG2 4.5Å
251	Y	89.8	Confident	90.6	Very high	19 Å²	19	45.3 Å²	45.3	8%	0.075	23%	0.229	C	C	.	.	G	3₁₀ helix	trans	-81.2	-15.4	175	-68.3	-95.6	0	0	0	112.8	K248 S249 T255 R392 I449 S452	K248-Y251 PolarHBondContact O-N 3.37Å; S249-Y251 PolarHBondContact O-N 3.41Å; Y251-T255 VanDerWaalsContact O-CB 3.24Å; Y251-T255 WeakPolarHBondContact O-CB 3.43Å; Y251-T255 PolarHBondContact O-N 3.18Å; Y251-T255 PolarHBondContact O-OG1 3.4Å; Y251-R392 HydrophobicContact CD1-CB 4.47Å; Y251-I449 HydrophobicContact CD1-CD1 4.23Å; Y251-I449 HydrophobicContact CD1-CG1 4.09Å; Y251-I449 HydrophobicContact CE1-CB 4.41Å; Y251-I449 HydrophobicContact CE1-CD1 4.17Å; Y251-I449 HydrophobicContact CE1-CG1 3.7Å; Y251-I449 HydrophobicContact CE1-CG2 4.02Å; Y251-I449 HydrophobicContact CE2-CG1 4.14Å; Y251-I449 HydrophobicContact CG-CG1 4.48Å; Y251-S452 PolarHBondContact OH-OG 3.36Å
252	A	93.1	Very high	90.8	Very high	1 Å²	1	40.4 Å²	40.4	1%	0.008	21%	0.207	C	C	.	.	H	α-helix	trans	-68.8	-51.5	-172.1	0	0	0	0	0	112.7	A65 T69 S249 T255 M256	A65-A252 HydrophobicContact CB-CB 3.97Å; T69-A252 HydrophobicContact CG2-CB 3.52Å; S249-A252 VanDerWaalsContact O-CB 3.27Å; S249-A252 WeakPolarHBondContact O-CB 3.43Å; S249-A252 PolarHBondContact O-N 2.95Å; A252-T255 PolarHBondContact O-N 3.37Å; A252-M256 WeakPolarHBondContact O-CG 3.42Å; A252-M256 PolarHBondContact O-N 3.27Å
253	I	92.6	Very high	91	Very high	41 Å²	41	35 Å²	35	21%	0.21	18%	0.179	C	C	.	.	H	α-helix	trans	-64.7	-46.5	-179.3	-53.2	177.2	0	0	0	111.5	L77 V81 T255 M256 A257 M441	L77-I253 HydrophobicContact CD1-CG1 4.02Å; L77-I253 HydrophobicContact CD2-CD1 3.86Å; L77-I253 HydrophobicContact CD2-CG1 3.91Å; V81-I253 HydrophobicContact CG2-CG2 4.28Å; I253-T255 VanDerWaalsContact C-N 3.33Å; I253-T255 PolarHBondContact O-N 3.1Å; I253-M256 PolarHBondContact O-N 3.35Å; I253-A257 WeakPolarHBondContact O-CB 3.4Å; I253-A257 PolarHBondContact O-N 3.38Å; I253-M441 HydrophobicContact CB-CG 4.18Å; I253-M441 HydrophobicContact CG2-CE 4.3Å; I253-M441 HydrophobicContact CG2-CG 3.42Å; I253-M441 VanDerWaalsContact CG2-CG 3.42Å; I253-M441 HydrophobicContact CG2-SD 3.97Å
254	P	94.3	Very high	90.9	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-56.2	-42.9	172	-29.6	37.8	0	0	0	113.6	A250 M256 A257 F258 G399 M441 S445 I449	A250-P254 WeakPolarHBondContact O-CD 3.42Å; A250-P254 WeakPolarHBondContact O-CG 3.29Å; P254-M256 VanDerWaalsContact C-N 3.35Å; P254-M256 PolarHBondContact O-N 2.84Å; P254-A257 PolarHBondContact O-N 2.67Å; P254-F258 VanDerWaalsContact O-CB 3.28Å; P254-F258 WeakPolarHBondContact O-CB 3.32Å; P254-F258 PolarHBondContact O-N 3.33Å; P254-G399 WeakPolarHBondContact O-CA 3.4Å; P254-M441 HydrophobicContact CG-SD 4.45Å; P254-S445 VanDerWaalsContact CG-CB 3.43Å; P254-I449 HydrophobicContact CG-CD1 4.49Å
255	T	94.9	Very high	91	Very high	2 Å²	2	28.8 Å²	28.8	1%	0.012	16%	0.157	C	C	.	.	H	α-helix	trans	-63.4	-41.7	178.4	-58.5	0	0	0	0	111.1	L62 Y251 A252 I253 S259 F395	L62-T255 HydrophobicContact CD2-CG2 4.32Å; Y251-T255 VanDerWaalsContact O-CB 3.24Å; Y251-T255 WeakPolarHBondContact O-CB 3.43Å; Y251-T255 PolarHBondContact O-N 3.18Å; Y251-T255 PolarHBondContact O-OG1 3.4Å; A252-T255 PolarHBondContact O-N 3.37Å; I253-T255 VanDerWaalsContact C-N 3.33Å; I253-T255 PolarHBondContact O-N 3.1Å; T255-S259 WeakPolarHBondContact O-CB 3.29Å; T255-S259 PolarHBondContact O-N 2.83Å; T255-S259 PolarHBondContact O-OG 2.91Å; T255-F395 HydrophobicContact CG2-CB 4.33Å; T255-F395 HydrophobicContact CG2-CD2 3.98Å; T255-F395 HydrophobicContact CG2-CG 4.41Å
256	M	95.7	Very high	91.3	Very high	0 Å²	0	22 Å²	22	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-67.4	-42.6	175.3	-68.5	175.2	-175.9	0	0	112.2	L62 F74 L77 L78 V81 A252 I253 P254 F258 S259 F260	L62-M256 HydrophobicContact CD2-CG 3.98Å; F74-M256 HydrophobicContact CD2-CE 3.19Å; F74-M256 HydrophobicContact CE2-CE 3.33Å; F74-M256 HydrophobicContact CG-CE 3.9Å; F74-M256 HydrophobicContact CZ-CE 4.12Å; L77-M256 HydrophobicContact CB-CE 3.87Å; L77-M256 HydrophobicContact CB-SD 3.63Å; L78-M256 HydrophobicContact CB-CE 4.46Å; L78-M256 HydrophobicContact CD1-CE 4.42Å; L78-M256 HydrophobicContact CD1-CG 4.36Å; L78-M256 HydrophobicContact CD1-SD 4.38Å; V81-M256 HydrophobicContact CB-CB 4.29Å; V81-M256 HydrophobicContact CG1-CB 4.09Å; V81-M256 HydrophobicContact CG2-CB 4.14Å; V81-M256 HydrophobicContact CG2-SD 4.48Å; A252-M256 WeakPolarHBondContact O-CG 3.42Å; A252-M256 PolarHBondContact O-N 3.27Å; I253-M256 PolarHBondContact O-N 3.35Å; P254-M256 VanDerWaalsContact C-N 3.35Å; P254-M256 PolarHBondContact O-N 2.84Å; M256-F258 VanDerWaalsContact C-N 3.32Å; M256-F258 PolarHBondContact O-N 2.75Å; M256-S259 PolarHBondContact O-N 3.42Å; M256-F260 WeakPolarHBondContact O-CD2 3.43Å; M256-F260 PolarHBondContact O-N 2.81Å
257	A	95.4	Very high	91.7	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-62	-41.9	177.5	0	0	0	0	0	111.2	I253 P254 L261 L407 F408 M441	I253-A257 WeakPolarHBondContact O-CB 3.4Å; I253-A257 PolarHBondContact O-N 3.38Å; P254-A257 PolarHBondContact O-N 2.67Å; A257-L261 WeakPolarHBondContact O-CB 3.42Å; A257-L261 PolarHBondContact O-N 3.34Å; A257-L407 WeakPolarHBondContact O-CD1 3.36Å; A257-F408 HydrophobicContact CB-CE2 4.08Å; A257-F408 HydrophobicContact CB-CZ 4.45Å; A257-M441 HydrophobicContact CB-CE 4.05Å
258	F	95.1	Very high	91.9	Very high	14 Å²	14	17.2 Å²	17.2	6%	0.061	10%	0.096	C	C	.	.	H	α-helix	trans	-62.2	-44.6	172.3	179.8	-89.1	0	0	0	111.9	Q127 A131 P254 M256 L261 F395 V398 S403	Q127-F258 VanDerWaalsContact NE2-CD2 3.33Å; A131-F258 HydrophobicContact CB-CE2 4.44Å; A131-F258 HydrophobicContact CB-CZ 4.09Å; P254-F258 VanDerWaalsContact O-CB 3.28Å; P254-F258 WeakPolarHBondContact O-CB 3.32Å; P254-F258 PolarHBondContact O-N 3.33Å; M256-F258 VanDerWaalsContact C-N 3.32Å; M256-F258 PolarHBondContact O-N 2.75Å; F258-L261 PolarHBondContact O-N 2.72Å; F258-F395 AromaticContact CD1-CD1 3.62Å; F258-F395 HydrophobicContact CD1-CD1 3.62Å; F258-F395 AromaticContact CD1-CE1 3.89Å; F258-F395 HydrophobicContact CD1-CE1 3.89Å; F258-F395 HydrophobicContact CD1-CG 4.41Å; F258-F395 AromaticContact CE1-CD1 3.45Å; F258-F395 HydrophobicContact CE1-CD1 3.45Å; F258-F395 VanDerWaalsContact CE1-CD1 3.45Å; F258-F395 AromaticContact CE1-CE1 3.35Å; F258-F395 HydrophobicContact CE1-CE1 3.35Å; F258-F395 HydrophobicContact CE1-CZ 4.42Å; F258-F395 HydrophobicContact CE2-CD1 4.48Å; F258-F395 HydrophobicContact CG-CD1 4.21Å; F258-F395 AromaticContact CZ-CD1 3.89Å; F258-F395 HydrophobicContact CZ-CD1 3.89Å; F258-F395 AromaticContact CZ-CE1 3.91Å; F258-F395 HydrophobicContact CZ-CE1 3.91Å; F258-V398 HydrophobicContact CD2-CB 4.21Å; F258-V398 HydrophobicContact CD2-CG1 3.94Å; F258-V398 HydrophobicContact CE2-CB 4.26Å; F258-V398 HydrophobicContact CE2-CG1 3.9Å; F258-S403 WeakPolarHBondContact CA-OG 3.33Å
259	S	95.4	Very high	92.3	Very high	1 Å²	1	11.9 Å²	11.9	1%	0.007	7%	0.073	C	C	.	.	H	α-helix	trans	-67	-38.2	-178.6	-56.7	0	0	0	0	112.8	I54 G58 T255 M256 L261 Y296	I54-S259 CarbonylContact C-O 3.59Å; I54-S259 WeakPolarHBondContact CG2-O 3.11Å; G58-S259 VanDerWaalsContact CA-OG 3.25Å; G58-S259 WeakPolarHBondContact CA-OG 3.23Å; T255-S259 WeakPolarHBondContact O-CB 3.29Å; T255-S259 PolarHBondContact O-N 2.83Å; T255-S259 PolarHBondContact O-OG 2.91Å; M256-S259 PolarHBondContact O-N 3.42Å; S259-L261 VanDerWaalsContact C-N 3.33Å; S259-Y296 PolarHBondContact O-OH 3.37Å
260	F	95.9	Very high	92.5	Very high	0 Å²	0	11.9 Å²	11.9	0%	0	7%	0.07	C	C	.	.	T	Hydrogen-bonded Turn	trans	-87.7	3.5	179	-78.6	-70.2	0	0	0	114.4	I54 L78 V81 A85 M256 C262 I289 F293 Y296 L407	I54-F260 HydrophobicContact CG2-CD1 4.01Å; I54-F260 HydrophobicContact CG2-CE1 4.44Å; L78-F260 HydrophobicContact CD1-CE2 3.57Å; L78-F260 HydrophobicContact CD1-CZ 4.09Å; L78-F260 HydrophobicContact CG-CE2 4.16Å; L78-F260 HydrophobicContact CG-CZ 4.39Å; V81-F260 HydrophobicContact CG1-CB 4.34Å; V81-F260 HydrophobicContact CG1-CD2 3.96Å; A85-F260 HydrophobicContact CB-CB 4.38Å; M256-F260 WeakPolarHBondContact O-CD2 3.43Å; M256-F260 PolarHBondContact O-N 2.81Å; F260-C262 PolarHBondContact O-N 3.19Å; F260-I289 HydrophobicContact CD1-CG2 4.42Å; F260-I289 HydrophobicContact CE1-CG2 4.24Å; F260-F293 HydrophobicContact CZ-CB 4.33Å; F260-F293 HydrophobicContact CZ-CD2 4.46Å; F260-Y296 HydrophobicContact CD1-CE2 4.38Å; F260-Y296 AromaticContact CE1-CD2 3.95Å; F260-Y296 HydrophobicContact CE1-CD2 3.95Å; F260-Y296 HydrophobicContact CE1-CE2 4.1Å; F260-Y296 AromaticContact CE2-CD2 3.91Å; F260-Y296 HydrophobicContact CE2-CD2 3.91Å; F260-Y296 HydrophobicContact CE2-CE2 4.28Å; F260-Y296 AromaticContact CZ-CD2 3.55Å; F260-Y296 HydrophobicContact CZ-CD2 3.55Å; F260-Y296 HydrophobicContact CZ-CE2 4.06Å; F260-L407 HydrophobicContact CB-CD1 4.3Å
261	L	95	Very high	92.5	Very high	10 Å²	10	14.6 Å²	14.6	5%	0.052	9%	0.087	C	C	.	.			trans	-76.2	101.5	-178.6	-173.9	75.1	0	0	0	111.9	Q127 A257 F258 S259 H263 L406 L407	Q127-L261 HydrophobicContact CB-CD2 4.48Å; Q127-L261 HydrophobicContact CG-CD2 3.26Å; A257-L261 WeakPolarHBondContact O-CB 3.42Å; A257-L261 PolarHBondContact O-N 3.34Å; F258-L261 PolarHBondContact O-N 2.72Å; S259-L261 VanDerWaalsContact C-N 3.33Å; L261-H263 HydrophobicContact CD1-CB 4.08Å; L261-L406 HydrophobicContact CD1-CB 3.68Å; L261-L406 HydrophobicContact CD2-CB 4.44Å; L261-L406 HydrophobicContact CD2-CD1 4.05Å; L261-L407 HydrophobicContact CB-CD1 4.25Å; L261-L407 HydrophobicContact CD1-CB 3.81Å; L261-L407 HydrophobicContact CD1-CD1 4.13Å; L261-L407 HydrophobicContact CD1-CG 4.31Å
262	C	94.2	Very high	92.3	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	11%	0.105	C	C	.	.			trans	-117.7	4.8	172.8	58	0	0	0	0	114	L50 A53 I54 F260 T264 A265 I266	L50-C262 HydrophobicContact CD1-CB 3.64Å; L50-C262 HydrophobicContact CG-CB 4.42Å; A53-C262 HydrophobicContact CB-CB 4.4Å; I54-C262 HydrophobicContact CD1-CB 4.34Å; I54-C262 HydrophobicContact CG1-CB 3.67Å; F260-C262 PolarHBondContact O-N 3.19Å; C262-T264 PolarHBondContact O-N 2.84Å; C262-T264 VanDerWaalsContact O-N 3.17Å; C262-A265 PolarHBondContact O-N 3.17Å; C262-I266 PolarHBondContact O-N 3.27Å
263	H	93	Very high	92.2	Very high	1 Å²	1	18.5 Å²	18.5	1%	0.005	11%	0.106	C	C	.	.	H	α-helix	trans	-62.7	-25.6	-172.8	-70.1	71.4	0	0	0	113.6	S88 Y104 L261 I266	S88-H263 VanDerWaalsContact CB-NE2 3.34Å; S88-H263 WeakPolarHBondContact CB-NE2 3.47Å; S88-H263 PolarHBondContact OG-NE2 3.49Å; Y104-H263 HydrophobicContact CE2-CB 3.91Å; L261-H263 HydrophobicContact CD1-CB 4.08Å; H263-I266 WeakPolarHBondContact O-CG2 3.25Å
264	T	88.3	Confident	92.1	Very high	24 Å²	24	19.9 Å²	19.9	15%	0.147	11%	0.111	C	C	.	.	H	α-helix	trans	-76.9	-24.5	176.4	60.1	0	0	0	0	112.6	I124 C262 L406	I124-T264 HydrophobicContact CB-CG2 4.46Å; I124-T264 HydrophobicContact CG1-CG2 3.99Å; I124-T264 HydrophobicContact CG2-CG2 4.16Å; C262-T264 PolarHBondContact O-N 2.84Å; C262-T264 VanDerWaalsContact O-N 3.17Å; T264-L406 HydrophobicContact CG2-CD1 4.03Å
265	A	89.9	Confident	91.9	Very high	23 Å²	23	28.5 Å²	28.5	19%	0.19	14%	0.144	C	C	.	.	H	α-helix	trans	-97.6	-24	-179.4	0	0	0	0	0	112.8	A53 C262 L267 P268 I269	A53-A265 HydrophobicContact CB-CB 3.77Å; C262-A265 PolarHBondContact O-N 3.17Å; A265-L267 PolarHBondContact O-N 3.05Å; A265-P268 WeakPolarHBondContact O-CD 3.19Å; A265-I269 HydrophobicContact CB-CD1 4.1Å; A265-I269 WeakPolarHBondContact O-CB 2.9Å; A265-I269 WeakPolarHBondContact O-CD1 3.41Å; A265-I269 WeakPolarHBondContact O-CG1 3.44Å; A265-I269 PolarHBondContact O-N 3.39Å
266	I	92	Very high	91.6	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-63.8	-43.1	-170.3	-161.8	171.6	0	0	0	113.9	L50 I89 L92 C262 H263 I269 Y270 M281 A285	L50-I266 HydrophobicContact CD1-CB 4.3Å; L50-I266 HydrophobicContact CD1-CG1 4.38Å; I89-I266 HydrophobicContact CB-CD1 3.95Å; I89-I266 HydrophobicContact CD1-CD1 3.77Å; I89-I266 HydrophobicContact CG1-CD1 3.57Å; I89-I266 HydrophobicContact CG2-CD1 3.22Å; L92-I266 HydrophobicContact CD2-CG2 3.88Å; C262-I266 PolarHBondContact O-N 3.27Å; H263-I266 WeakPolarHBondContact O-CG2 3.25Å; I266-I269 PolarHBondContact O-N 3.06Å; I266-Y270 WeakPolarHBondContact O-CB 3.34Å; I266-Y270 PolarHBondContact O-N 3.42Å; I266-M281 HydrophobicContact CD1-CE 4.23Å; I266-M281 HydrophobicContact CG1-CE 3.36Å; I266-M281 WeakPolarHBondContact O-CE 3.35Å; I266-A285 HydrophobicContact CD1-CB 4.36Å
267	L	89.8	Confident	91.5	Very high	2 Å²	2	34.6 Å²	34.6	1%	0.01	18%	0.183	C	C	.	.	H	α-helix	trans	-71.2	-42.1	-178.3	-60.4	-176.9	0	0	0	112.9	L92 C96 Y104 A265 I269 Y270 C271	L92-L267 HydrophobicContact CD2-CD1 4.04Å; L92-L267 HydrophobicContact CD2-CD2 3.87Å; L92-L267 HydrophobicContact CD2-CG 3.9Å; L92-L267 HydrophobicContact CG-CD1 4.42Å; L92-L267 HydrophobicContact CG-CD2 4.19Å; C96-L267 WeakPolarHBondContact SG-CD2 3.39Å; Y104-L267 HydrophobicContact CD2-CD1 4.21Å; Y104-L267 HydrophobicContact CG-CD1 4.47Å; A265-L267 PolarHBondContact O-N 3.05Å; L267-I269 VanDerWaalsContact C-N 3.34Å; L267-I269 PolarHBondContact O-N 2.94Å; L267-Y270 WeakPolarHBondContact O-CB 3.11Å; L267-Y270 PolarHBondContact O-N 3.46Å; L267-C271 PolarHBondContact O-N 3.21Å; L267-C271 VanDerWaalsContact O-N 3.14Å
268	P	87.8	Confident	91.5	Very high	63 Å²	63	37 Å²	37	41%	0.409	19%	0.193	S	C	.	.	H	α-helix	trans	-55.1	-46.2	167.3	-28.1	34.7	0	0	0	113.3	A265 Y270 C271 E272	A265-P268 WeakPolarHBondContact O-CD 3.19Å; P268-Y270 VanDerWaalsContact C-N 3.26Å; P268-Y270 PolarHBondContact O-N 3.48Å; P268-C271 WeakPolarHBondContact O-CB 3.25Å; P268-C271 PolarHBondContact O-N 3.22Å; P268-C271 VanDerWaalsContact O-N 3.17Å; P268-E272 PolarHBondContact O-N 3.21Å; P268-E272 VanDerWaalsContact O-N 3.17Å
269	I	90.2	Very high	91.4	Very high	10 Å²	10	41 Å²	41	5%	0.051	22%	0.219	C	C	.	.	H	α-helix	trans	-64.1	-34.5	178.3	-66.1	166.8	0	0	0	111	C46 N49 L50 A265 I266 L267 C271 E272 L273 M281	C46-I269 HydrophobicContact CB-CG2 3.64Å; N49-I269 HydrophobicContact CB-CD1 3.93Å; N49-I269 HydrophobicContact CB-CG1 4.32Å; L50-I269 HydrophobicContact CB-CD1 3.99Å; L50-I269 HydrophobicContact CD1-CD1 4.03Å; A265-I269 HydrophobicContact CB-CD1 4.1Å; A265-I269 WeakPolarHBondContact O-CB 2.9Å; A265-I269 WeakPolarHBondContact O-CD1 3.41Å; A265-I269 WeakPolarHBondContact O-CG1 3.44Å; A265-I269 PolarHBondContact O-N 3.39Å; I266-I269 PolarHBondContact O-N 3.06Å; L267-I269 VanDerWaalsContact C-N 3.34Å; L267-I269 PolarHBondContact O-N 2.94Å; I269-C271 VanDerWaalsContact C-N 3.34Å; I269-C271 PolarHBondContact O-N 3.11Å; I269-E272 PolarHBondContact O-N 3.08Å; I269-L273 PolarHBondContact O-N 2.87Å; I269-M281 HydrophobicContact CB-CE 4.07Å; I269-M281 HydrophobicContact CG2-CE 3.78Å; I269-M281 HydrophobicContact CG2-SD 4.35Å
270	Y	91.2	Very high	91.5	Very high	20 Å²	20	44.4 Å²	44.4	8%	0.078	23%	0.231	C	C	.	.	H	α-helix	trans	-61.4	-41.8	175	-179.4	-129.8	0	0	0	112.1	L93 C96 I266 L267 P268 E272 L273 P276 M281	L93-Y270 HydrophobicContact CD2-CG 4.45Å; C96-Y270 HydrophobicContact CB-CE1 4.41Å; I266-Y270 WeakPolarHBondContact O-CB 3.34Å; I266-Y270 PolarHBondContact O-N 3.42Å; L267-Y270 WeakPolarHBondContact O-CB 3.11Å; L267-Y270 PolarHBondContact O-N 3.46Å; P268-Y270 VanDerWaalsContact C-N 3.26Å; P268-Y270 PolarHBondContact O-N 3.48Å; Y270-E272 VanDerWaalsContact C-N 3.31Å; Y270-E272 PolarHBondContact O-N 2.91Å; Y270-L273 PolarHBondContact O-N 3.01Å; Y270-P276 HydrophobicContact CD2-CB 4.2Å; Y270-P276 HydrophobicContact CE2-CB 3.84Å; Y270-P276 WeakPolarHBondContact O-CB 3.48Å; Y270-M281 HydrophobicContact CD2-CB 3.47Å; Y270-M281 VanDerWaalsContact CD2-CB 3.47Å; Y270-M281 HydrophobicContact CD2-CG 3.54Å; Y270-M281 HydrophobicContact CD2-SD 4.17Å; Y270-M281 HydrophobicContact CE2-CB 3.83Å; Y270-M281 HydrophobicContact CE2-CG 4.36Å; Y270-M281 HydrophobicContact CG-CB 4.45Å; Y270-M281 HydrophobicContact CG-CG 4.08Å
271	C	87.9	Confident	91.4	Very high	75 Å²	75	44.4 Å²	44.4	51%	0.507	23%	0.231	S	C	.	.	H	α-helix	trans	-68.3	-28.8	176.1	-68	0	0	0	0	113.3	N102 L267 P268 I269	N102-C271 VanDerWaalsContact CB-SG 3.53Å; L267-C271 PolarHBondContact O-N 3.21Å; L267-C271 VanDerWaalsContact O-N 3.14Å; P268-C271 WeakPolarHBondContact O-CB 3.25Å; P268-C271 PolarHBondContact O-N 3.22Å; P268-C271 VanDerWaalsContact O-N 3.17Å; I269-C271 VanDerWaalsContact C-N 3.34Å; I269-C271 PolarHBondContact O-N 3.11Å
272	E	87.6	Confident	91.5	Very high	98 Å²	98	45 Å²	45	46%	0.458	23%	0.234	S	C	.	.	H	α-helix	trans	-82.5	-20.8	178.6	-70.8	177.8	-176.1	0	0	113.2	G40 A41 P268 I269 Y270	G40-E272 CarbonylContact C-O 3.41Å; G40-E272 WeakPolarHBondContact CA-O 3.48Å; A41-E272 HydrophobicContact CB-CB 4.48Å; A41-E272 PolarHBondContact N-O 3.33Å; P268-E272 PolarHBondContact O-N 3.21Å; P268-E272 VanDerWaalsContact O-N 3.17Å; I269-E272 PolarHBondContact O-N 3.08Å; Y270-E272 VanDerWaalsContact C-N 3.31Å; Y270-E272 PolarHBondContact O-N 2.91Å
273	L	89.8	Confident	91.7	Very high	4 Å²	4	49 Å²	49	2%	0.021	26%	0.255	C	S	.	.	B	Isolated β-bridge	trans	-62	133.5	-175.4	179.2	64.2	0	0	0	112.4	I43 C46 I269 Y270 R275 P276 R280 M281 V284	I43-L273 HydrophobicContact CG1-CD1 4.11Å; C46-L273 HydrophobicContact CB-CD1 4.25Å; C46-L273 VanDerWaalsContact SG-CD1 3.57Å; I269-L273 PolarHBondContact O-N 2.87Å; Y270-L273 PolarHBondContact O-N 3.01Å; L273-R275 PolarHBondContact O-N 3.36Å; L273-P276 WeakPolarHBondContact O-CD 3.17Å; L273-R280 HydrophobicContact CD2-CB 3.98Å; L273-M281 HydrophobicContact CD2-CB 4.21Å; L273-M281 HydrophobicContact CD2-SD 4.15Å; L273-V284 HydrophobicContact CD1-CG2 4.45Å
274	E	90.5	Very high	91.9	Very high	70 Å²	70	48.9 Å²	48.9	33%	0.327	26%	0.255	S	S	.	.	S	Bend	trans	-63.1	121.1	173	-161	-161.9	160.2	0	0	110.9	A41 R280	A41-E274 WeakPolarHBondContact O-CB 3.25Å; A41-E274 PolarHBondContact O-N 3.06Å; E274-R280 PolarHBondContact O-NE 2.71Å; E274-R280 PolarHBondContact O-NH2 3.26Å
275	R	89.9	Confident	92.3	Very high	181 Å²	181	47.8 Å²	47.8	68%	0.683	25%	0.248	S	C	*	.	S	Bend	trans	55.7	73	-174.4	-57	174.5	-163.3	-177.4	1.8	110.3	L273 T277 R280	L273-R275 PolarHBondContact O-N 3.36Å; R275-T277 PolarHBondContact O-N 3.17Å; R275-R280 WeakPolarHBondContact O-CD 3.13Å; R275-R280 PolarHBondContact O-NE 2.84Å
276	P	89.6	Confident	92.7	Very high	71 Å²	71	49.7 Å²	49.7	46%	0.461	26%	0.255	S	S	.	.			trans	-67.3	119.6	-173.3	28.6	-34	0	0	0	110.1	Y270 L273	Y270-P276 HydrophobicContact CD2-CB 4.2Å; Y270-P276 HydrophobicContact CE2-CB 3.84Å; Y270-P276 WeakPolarHBondContact O-CB 3.48Å; L273-P276 WeakPolarHBondContact O-CD 3.17Å
277	T	93.7	Very high	92.9	Very high	60 Å²	60	53.9 Å²	53.9	37%	0.368	28%	0.276	S	S	.	.			trans	-138.6	150.5	170.8	69.2	0	0	0	0	109.5	R275 T279 R280 M281	R275-T277 PolarHBondContact O-N 3.17Å; T277-T279 VanDerWaalsContact C-N 3.26Å; T277-T279 PolarHBondContact O-N 3.29Å; T277-R280 PolarHBondContact O-N 3.48Å; T277-R280 WeakPolarHBondContact OG1-CB 3.41Å; T277-R280 WeakPolarHBondContact OG1-CD 3.39Å; T277-R280 WeakPolarHBondContact OG1-CG 2.99Å; T277-R280 PolarHBondContact OG1-N 2.89Å; T277-M281 PolarHBondContact O-N 2.72Å
278	K	93.7	Very high	93.3	Very high	49 Å²	49	53.8 Å²	53.8	21%	0.213	28%	0.276	C	S	.	.	H	α-helix	trans	-47.8	-49.5	176.1	179.8	-173.6	175.7	-175.3	0	111.7	H90 L93 T94 R280 M281 Q282	H90-K278 PolarHBondContact CE1-NZ 3.18Å; L93-K278 HydrophobicContact CB-CG 4.16Å; T94-K278 WeakPolarHBondContact OG1-CE 3.35Å; T94-K278 PolarHBondContact OG1-NZ 2.9Å; K278-R280 PolarHBondContact O-N 2.88Å; K278-M281 PolarHBondContact O-N 3.44Å; K278-Q282 VanDerWaalsContact O-CB 3.3Å; K278-Q282 WeakPolarHBondContact O-CB 3.47Å; K278-Q282 PolarHBondContact O-N 3.47Å
279	T	95	Very high	93.7	Very high	98 Å²	98	50.9 Å²	50.9	60%	0.601	26%	0.257	S	S	*	.	H	α-helix	trans	-63.9	-43	-177.1	-47.4	0	0	0	0	112.7	T277 Q282 N283	T277-T279 VanDerWaalsContact C-N 3.26Å; T277-T279 PolarHBondContact O-N 3.29Å; T279-Q282 PolarHBondContact O-N 3.26Å; T279-N283 PolarHBondContact O-N 3.11Å
280	R	95.6	Very high	94.1	Very high	73 Å²	73	54 Å²	54	28%	0.275	28%	0.28	S	S	.	.	H	α-helix	trans	-66.8	-42.1	179.2	-72.3	170.3	65.4	99.7	-4.5	111	L273 E274 R275 T277 K278 N283 V284	L273-R280 HydrophobicContact CD2-CB 3.98Å; E274-R280 PolarHBondContact O-NE 2.71Å; E274-R280 PolarHBondContact O-NH2 3.26Å; R275-R280 WeakPolarHBondContact O-CD 3.13Å; R275-R280 PolarHBondContact O-NE 2.84Å; T277-R280 PolarHBondContact O-N 3.48Å; T277-R280 WeakPolarHBondContact OG1-CB 3.41Å; T277-R280 WeakPolarHBondContact OG1-CD 3.39Å; T277-R280 WeakPolarHBondContact OG1-CG 2.99Å; T277-R280 PolarHBondContact OG1-N 2.89Å; K278-R280 PolarHBondContact O-N 2.88Å; R280-N283 WeakPolarHBondContact O-CB 3.15Å; R280-N283 PolarHBondContact O-N 3.37Å; R280-V284 WeakPolarHBondContact O-CG2 3.39Å; R280-V284 PolarHBondContact O-N 2.98Å
281	M	95.6	Very high	94.3	Very high	0 Å²	0	55.7 Å²	55.7	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-69.7	-35.6	177.8	-167.2	59.7	-161.8	0	0	112.6	L93 I266 I269 Y270 L273 T277 K278 N283 V284 A285	L93-M281 HydrophobicContact CD1-CB 4.1Å; L93-M281 HydrophobicContact CD1-CG 4.01Å; L93-M281 HydrophobicContact CD2-CB 4.24Å; L93-M281 HydrophobicContact CD2-CG 3.78Å; I266-M281 HydrophobicContact CD1-CE 4.23Å; I266-M281 HydrophobicContact CG1-CE 3.36Å; I266-M281 WeakPolarHBondContact O-CE 3.35Å; I269-M281 HydrophobicContact CB-CE 4.07Å; I269-M281 HydrophobicContact CG2-CE 3.78Å; I269-M281 HydrophobicContact CG2-SD 4.35Å; Y270-M281 HydrophobicContact CD2-CB 3.47Å; Y270-M281 VanDerWaalsContact CD2-CB 3.47Å; Y270-M281 HydrophobicContact CD2-CG 3.54Å; Y270-M281 HydrophobicContact CD2-SD 4.17Å; Y270-M281 HydrophobicContact CE2-CB 3.83Å; Y270-M281 HydrophobicContact CE2-CG 4.36Å; Y270-M281 HydrophobicContact CG-CB 4.45Å; Y270-M281 HydrophobicContact CG-CG 4.08Å; L273-M281 HydrophobicContact CD2-CB 4.21Å; L273-M281 HydrophobicContact CD2-SD 4.15Å; T277-M281 PolarHBondContact O-N 2.72Å; K278-M281 PolarHBondContact O-N 3.44Å; M281-N283 VanDerWaalsContact C-N 3.32Å; M281-N283 PolarHBondContact O-N 2.69Å; M281-V284 HydrophobicContact CE-CG1 4.3Å; M281-V284 WeakPolarHBondContact O-CB 3.49Å; M281-V284 PolarHBondContact O-N 3.27Å; M281-V284 HydrophobicContact SD-CB 4.25Å; M281-V284 HydrophobicContact SD-CG1 4.38Å; M281-A285 PolarHBondContact O-N 2.9Å
282	Q	96.8	Very high	94.7	Very high	23 Å²	23	52.1 Å²	52.1	11%	0.107	27%	0.266	C	S	.	.	H	α-helix	trans	-61.9	-41.2	171.3	-171.9	70.1	60.3	0	0	111	H90 L93 K278 T279 A285 N286	H90-Q282 PolarHBondContact ND1-OE1 3.01Å; H90-Q282 VanDerWaalsContact ND1-OE1 3.08Å; L93-Q282 HydrophobicContact CD1-CB 4.32Å; K278-Q282 VanDerWaalsContact O-CB 3.3Å; K278-Q282 WeakPolarHBondContact O-CB 3.47Å; K278-Q282 PolarHBondContact O-N 3.47Å; T279-Q282 PolarHBondContact O-N 3.26Å; Q282-A285 PolarHBondContact O-N 3.49Å; Q282-N286 PolarHBondContact NE2-OD1 3.38Å; Q282-N286 WeakPolarHBondContact O-CB 3.48Å; Q282-N286 PolarHBondContact O-N 3.49Å; Q282-N286 PolarHBondContact O-OD1 2.99Å
283	N	97.1	Very high	95.2	Very high	83 Å²	83	50.1 Å²	50.1	44%	0.444	26%	0.256	S	S	.	.	H	α-helix	trans	-62.9	-41.4	174.8	-74.6	-3.7	0	0	0	112	T279 R280 M281 A285 N286 I287	T279-N283 PolarHBondContact O-N 3.11Å; R280-N283 WeakPolarHBondContact O-CB 3.15Å; R280-N283 PolarHBondContact O-N 3.37Å; M281-N283 VanDerWaalsContact C-N 3.32Å; M281-N283 PolarHBondContact O-N 2.69Å; N283-A285 VanDerWaalsContact C-N 3.35Å; N283-A285 PolarHBondContact O-N 2.93Å; N283-N286 PolarHBondContact O-N 3.07Å; N283-I287 VanDerWaalsContact O-CG1 3.28Å; N283-I287 WeakPolarHBondContact O-CG1 3.45Å; N283-I287 PolarHBondContact O-N 2.97Å
284	V	97.2	Very high	95.6	Very high	0 Å²	0	54.5 Å²	54.5	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-56.3	-50.4	172.1	170.7	0	0	0	0	110.1	I43 C46 V47 L50 L273 R280 M281 N286 I287 S288	I43-V284 HydrophobicContact CG2-CG2 3.9Å; C46-V284 HydrophobicContact CB-CG1 3.87Å; C46-V284 HydrophobicContact CB-CG2 4.07Å; V47-V284 HydrophobicContact CG2-CB 4.3Å; V47-V284 HydrophobicContact CG2-CG1 3.96Å; V47-V284 HydrophobicContact CG2-CG2 4.35Å; L50-V284 HydrophobicContact CD2-CG1 4.13Å; L273-V284 HydrophobicContact CD1-CG2 4.45Å; R280-V284 WeakPolarHBondContact O-CG2 3.39Å; R280-V284 PolarHBondContact O-N 2.98Å; M281-V284 HydrophobicContact CE-CG1 4.3Å; M281-V284 WeakPolarHBondContact O-CB 3.49Å; M281-V284 PolarHBondContact O-N 3.27Å; M281-V284 HydrophobicContact SD-CB 4.25Å; M281-V284 HydrophobicContact SD-CG1 4.38Å; V284-N286 PolarHBondContact O-N 3.4Å; V284-I287 PolarHBondContact O-N 3.15Å; V284-S288 WeakPolarHBondContact O-CB 3.48Å; V284-S288 PolarHBondContact O-N 3.41Å; V284-S288 PolarHBondContact O-OG 3.37Å; V284-S288 VanDerWaalsContact O-OG 3.05Å
285	A	97.4	Very high	95.8	Very high	0 Å²	0	51.7 Å²	51.7	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-61.1	-44.2	179	0	0	0	0	0	113.2	L50 I89 I266 M281 Q282 N283 I287 S288 I289	L50-A285 HydrophobicContact CD2-CB 4.19Å; I89-A285 HydrophobicContact CD1-CB 4.23Å; I89-A285 HydrophobicContact CG2-CB 3.82Å; I266-A285 HydrophobicContact CD1-CB 4.36Å; M281-A285 PolarHBondContact O-N 2.9Å; Q282-A285 PolarHBondContact O-N 3.49Å; N283-A285 VanDerWaalsContact C-N 3.35Å; N283-A285 PolarHBondContact O-N 2.93Å; A285-I287 PolarHBondContact O-N 3.03Å; A285-S288 PolarHBondContact O-N 3.41Å; A285-I289 WeakPolarHBondContact O-CB 3.44Å; A285-I289 PolarHBondContact O-N 2.79Å
286	N	97.8	Very high	96.2	Very high	63 Å²	63	43 Å²	43	34%	0.337	23%	0.233	S	C	.	.	H	α-helix	trans	-60	-47.3	178.6	-68.2	-4.9	0	0	0	111.3	L86 Q282 N283 V284 S290	L86-N286 WeakPolarHBondContact CD2-OD1 3.31Å; Q282-N286 PolarHBondContact NE2-OD1 3.38Å; Q282-N286 WeakPolarHBondContact O-CB 3.48Å; Q282-N286 PolarHBondContact O-N 3.49Å; Q282-N286 PolarHBondContact O-OD1 2.99Å; N283-N286 PolarHBondContact O-N 3.07Å; V284-N286 PolarHBondContact O-N 3.4Å; N286-S290 WeakPolarHBondContact O-CB 3.28Å; N286-S290 PolarHBondContact O-N 2.9Å
287	I	97.6	Very high	96.6	Very high	88 Å²	88	42.3 Å²	42.3	45%	0.451	22%	0.223	S	C	.	.	H	α-helix	trans	-66	-48.2	178.9	-65.1	167	0	0	0	110.4	V47 N283 V284 A285 I289 S290 L291	V47-I287 HydrophobicContact CG1-CG2 3.9Å; V47-I287 HydrophobicContact CG2-CB 4.19Å; V47-I287 HydrophobicContact CG2-CG2 4.09Å; N283-I287 VanDerWaalsContact O-CG1 3.28Å; N283-I287 WeakPolarHBondContact O-CG1 3.45Å; N283-I287 PolarHBondContact O-N 2.97Å; V284-I287 PolarHBondContact O-N 3.15Å; A285-I287 PolarHBondContact O-N 3.03Å; I287-I289 PolarHBondContact O-N 2.87Å; I287-S290 PolarHBondContact O-N 2.87Å; I287-L291 WeakPolarHBondContact O-CB 3.43Å; I287-L291 PolarHBondContact O-N 3.3Å
288	S	97.1	Very high	96.8	Very high	0 Å²	0	41.2 Å²	41.2	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-62.8	-43.4	-178.1	-66	0	0	0	0	113.1	V47 V284 A285 S292	V47-S288 VanDerWaalsContact CA-OG 3.29Å; V47-S288 WeakPolarHBondContact CA-OG 3.34Å; V47-S288 PolarHBondContact O-OG 3.36Å; V284-S288 WeakPolarHBondContact O-CB 3.48Å; V284-S288 PolarHBondContact O-N 3.41Å; V284-S288 PolarHBondContact O-OG 3.37Å; V284-S288 VanDerWaalsContact O-OG 3.05Å; A285-S288 PolarHBondContact O-N 3.41Å; S288-S292 VanDerWaalsContact O-CB 3.26Å; S288-S292 WeakPolarHBondContact O-CB 3.39Å; S288-S292 PolarHBondContact O-N 3.17Å; S288-S292 PolarHBondContact O-OG 3.45Å
289	I	97.3	Very high	97	Very high	2 Å²	2	38.9 Å²	38.9	1%	0.01	21%	0.206	C	C	.	.	H	α-helix	trans	-71.8	-39.7	178.4	-71	174.1	0	0	0	110.6	I54 A85 L86 I89 F260 A285 I287 S292 F293	I54-I289 HydrophobicContact CD1-CG1 3.78Å; A85-I289 HydrophobicContact CB-CD1 4.24Å; L86-I289 HydrophobicContact CD1-CB 4.45Å; L86-I289 HydrophobicContact CD1-CG2 4Å; L86-I289 HydrophobicContact CD2-CB 4.01Å; L86-I289 HydrophobicContact CD2-CD1 3.6Å; L86-I289 HydrophobicContact CD2-CG1 4.28Å; L86-I289 HydrophobicContact CD2-CG2 4.36Å; L86-I289 HydrophobicContact CG-CB 4.12Å; L86-I289 HydrophobicContact CG-CD1 3.72Å; L86-I289 HydrophobicContact CG-CG1 4.5Å; L86-I289 HydrophobicContact CG-CG2 3.91Å; I89-I289 HydrophobicContact CD1-CD1 3.56Å; F260-I289 HydrophobicContact CD1-CG2 4.42Å; F260-I289 HydrophobicContact CE1-CG2 4.24Å; A285-I289 WeakPolarHBondContact O-CB 3.44Å; A285-I289 PolarHBondContact O-N 2.79Å; I287-I289 PolarHBondContact O-N 2.87Å; I289-S292 PolarHBondContact O-N 3.28Å; I289-F293 WeakPolarHBondContact O-CB 3.31Å; I289-F293 PolarHBondContact O-N 2.75Å
290	S	97.3	Very high	97.1	Very high	77 Å²	77	34.2 Å²	34.2	54%	0.538	18%	0.177	S	C	.	.	H	α-helix	trans	-62.4	-45.4	177	-178.7	0	0	0	0	112.1	N286 I287 F293 L294	N286-S290 WeakPolarHBondContact O-CB 3.28Å; N286-S290 PolarHBondContact O-N 2.9Å; I287-S290 PolarHBondContact O-N 2.87Å; S290-F293 WeakPolarHBondContact O-CB 3.42Å; S290-F293 PolarHBondContact O-N 2.92Å; S290-L294 PolarHBondContact O-N 3.06Å
291	L	96.4	Very high	97.1	Very high	55 Å²	55	32.2 Å²	32.2	29%	0.288	17%	0.172	S	C	.	.	H	α-helix	trans	-69.3	-37.9	178.8	-172.3	51.7	0	0	0	111.9	M51 F196 I287 L294 L295	M51-L291 HydrophobicContact CE-CB 3.87Å; M51-L291 HydrophobicContact CE-CD2 3.31Å; M51-L291 HydrophobicContact CE-CG 3.41Å; M51-L291 VanDerWaalsContact CE-CG 3.41Å; M51-L291 HydrophobicContact SD-CB 4.24Å; M51-L291 HydrophobicContact SD-CD2 3.73Å; M51-L291 HydrophobicContact SD-CG 4.22Å; F196-L291 HydrophobicContact CE2-CD2 3.96Å; F196-L291 HydrophobicContact CE2-CG 4.23Å; F196-L291 HydrophobicContact CZ-CD2 3.96Å; I287-L291 WeakPolarHBondContact O-CB 3.43Å; I287-L291 PolarHBondContact O-N 3.3Å; L291-L294 PolarHBondContact O-N 3.44Å; L291-L295 PolarHBondContact O-N 3.35Å; L291-L295 VanDerWaalsContact O-N 3.17Å
292	S	96.8	Very high	97.2	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-64.1	-43.4	172.5	-57.2	0	0	0	0	112.3	S288 I289 L294 L295 Y296	S288-S292 VanDerWaalsContact O-CB 3.26Å; S288-S292 WeakPolarHBondContact O-CB 3.39Å; S288-S292 PolarHBondContact O-N 3.17Å; S288-S292 PolarHBondContact O-OG 3.45Å; I289-S292 PolarHBondContact O-N 3.28Å; S292-L294 VanDerWaalsContact C-N 3.33Å; S292-L294 PolarHBondContact O-N 3.05Å; S292-L295 PolarHBondContact O-N 2.93Å; S292-Y296 VanDerWaalsContact O-CB 3.23Å; S292-Y296 WeakPolarHBondContact O-CB 3.42Å; S292-Y296 PolarHBondContact O-N 3.3Å
293	F	97.4	Very high	97.1	Very high	56 Å²	56	33.3 Å²	33.3	25%	0.246	18%	0.176	C	C	.	.	H	α-helix	trans	-56.5	-46.5	175.8	172.4	-84.6	0	0	0	111.4	L78 V79 F260 I289 S290 Y296 F297	L78-F293 HydrophobicContact CB-CE2 4.05Å; L78-F293 HydrophobicContact CD2-CD2 3.67Å; L78-F293 HydrophobicContact CD2-CE2 3.5Å; L78-F293 HydrophobicContact CD2-CG 4.37Å; L78-F293 HydrophobicContact CD2-CZ 4.06Å; L78-F293 HydrophobicContact CG-CD2 3.77Å; L78-F293 HydrophobicContact CG-CE2 3.66Å; V79-F293 HydrophobicContact CB-CE2 4.49Å; V79-F293 HydrophobicContact CG2-CE2 3.73Å; V79-F293 HydrophobicContact CG2-CZ 3.7Å; F260-F293 HydrophobicContact CZ-CB 4.33Å; F260-F293 HydrophobicContact CZ-CD2 4.46Å; I289-F293 WeakPolarHBondContact O-CB 3.31Å; I289-F293 PolarHBondContact O-N 2.75Å; S290-F293 WeakPolarHBondContact O-CB 3.42Å; S290-F293 PolarHBondContact O-N 2.92Å; F293-Y296 PolarHBondContact O-N 3.33Å; F293-F297 VanDerWaalsContact O-CB 3.3Å; F293-F297 WeakPolarHBondContact O-CB 3.03Å; F293-F297 PolarHBondContact O-N 2.99Å
294	L	97.2	Very high	97	Very high	96 Å²	96	29.6 Å²	29.6	50%	0.503	16%	0.156	S	C	.	.	H	α-helix	trans	-60.9	-49	178.8	-179.5	65.5	0	0	0	111.5	S290 L291 S292 Y296 F297 V298	S290-L294 PolarHBondContact O-N 3.06Å; L291-L294 PolarHBondContact O-N 3.44Å; S292-L294 VanDerWaalsContact C-N 3.33Å; S292-L294 PolarHBondContact O-N 3.05Å; L294-Y296 VanDerWaalsContact C-N 3.34Å; L294-Y296 PolarHBondContact O-N 2.89Å; L294-F297 PolarHBondContact O-N 3.23Å; L294-V298 HydrophobicContact CD1-CG2 4.19Å; L294-V298 WeakPolarHBondContact O-CB 3.18Å; L294-V298 VanDerWaalsContact O-CG2 3.3Å; L294-V298 WeakPolarHBondContact O-CG2 3.44Å; L294-V298 PolarHBondContact O-N 3.01Å
295	L	96.6	Very high	96.8	Very high	10 Å²	10	31.1 Å²	31.1	5%	0.052	16%	0.164	C	C	.	.	H	α-helix	trans	-65.9	-38.1	-179.1	-72.2	169.9	0	0	0	112.3	M55 F196 L200 T203 L291 S292 S299	M55-L295 HydrophobicContact CE-CB 4.33Å; M55-L295 HydrophobicContact CE-CD1 3.2Å; M55-L295 HydrophobicContact CE-CG 4.31Å; M55-L295 HydrophobicContact SD-CD1 4.06Å; F196-L295 HydrophobicContact CD2-CD1 4.39Å; F196-L295 HydrophobicContact CE2-CD1 3.68Å; L200-L295 HydrophobicContact CD1-CD2 3.8Å; T203-L295 HydrophobicContact CG2-CD2 3.93Å; L291-L295 PolarHBondContact O-N 3.35Å; L291-L295 VanDerWaalsContact O-N 3.17Å; S292-L295 PolarHBondContact O-N 2.93Å; L295-S299 WeakPolarHBondContact O-CB 3.48Å; L295-S299 PolarHBondContact O-N 3.37Å; L295-S299 PolarHBondContact O-OG 3.17Å
296	Y	97.6	Very high	96.6	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-64.2	-47.2	174	-77.2	-1.1	0	0	0	112.5	I54 M55 I59 L62 S259 F260 S292 F293 L294 A300	I54-Y296 VanDerWaalsContact C-OH 3.28Å; I54-Y296 HydrophobicContact CG2-CE2 3.92Å; I54-Y296 PolarHBondContact O-OH 2.85Å; M55-Y296 WeakPolarHBondContact CA-OH 3.47Å; M55-Y296 HydrophobicContact CB-CE1 4.44Å; M55-Y296 HydrophobicContact CG-CE1 4.34Å; M55-Y296 PolarHBondContact O-OH 3.49Å; I59-Y296 HydrophobicContact CB-CD1 4.14Å; I59-Y296 HydrophobicContact CB-CE1 3.77Å; I59-Y296 HydrophobicContact CD1-CD1 3.88Å; I59-Y296 HydrophobicContact CD1-CE1 4.1Å; I59-Y296 HydrophobicContact CG1-CD1 3.7Å; I59-Y296 HydrophobicContact CG1-CE1 3.86Å; L62-Y296 HydrophobicContact CD1-CD1 3.68Å; L62-Y296 HydrophobicContact CD1-CD2 3.5Å; L62-Y296 HydrophobicContact CD1-CE1 4.11Å; L62-Y296 HydrophobicContact CD1-CE2 3.98Å; L62-Y296 HydrophobicContact CD1-CG 3.29Å; S259-Y296 PolarHBondContact O-OH 3.37Å; F260-Y296 HydrophobicContact CD1-CE2 4.38Å; F260-Y296 AromaticContact CE1-CD2 3.95Å; F260-Y296 HydrophobicContact CE1-CD2 3.95Å; F260-Y296 HydrophobicContact CE1-CE2 4.1Å; F260-Y296 AromaticContact CE2-CD2 3.91Å; F260-Y296 HydrophobicContact CE2-CD2 3.91Å; F260-Y296 HydrophobicContact CE2-CE2 4.28Å; F260-Y296 AromaticContact CZ-CD2 3.55Å; F260-Y296 HydrophobicContact CZ-CD2 3.55Å; F260-Y296 HydrophobicContact CZ-CE2 4.06Å; S292-Y296 VanDerWaalsContact O-CB 3.23Å; S292-Y296 WeakPolarHBondContact O-CB 3.42Å; S292-Y296 PolarHBondContact O-N 3.3Å; F293-Y296 PolarHBondContact O-N 3.33Å; L294-Y296 VanDerWaalsContact C-N 3.34Å; L294-Y296 PolarHBondContact O-N 2.89Å; Y296-A300 WeakPolarHBondContact O-CB 3.29Å; Y296-A300 PolarHBondContact O-N 3.37Å
297	F	97.8	Very high	96.2	Very high	56 Å²	56	28.3 Å²	28.3	25%	0.246	15%	0.149	C	C	.	.	H	α-helix	trans	-62.5	-49.4	179.2	-179.7	-102.1	0	0	0	111.5	F74 S75 L78 F293 L294 A300 L301	F74-F297 HydrophobicContact CE1-CD2 4.37Å; S75-F297 WeakPolarHBondContact OG-CE2 3.43Å; L78-F297 HydrophobicContact CD2-CB 3.86Å; L78-F297 HydrophobicContact CD2-CD2 4.28Å; F293-F297 VanDerWaalsContact O-CB 3.3Å; F293-F297 WeakPolarHBondContact O-CB 3.03Å; F293-F297 PolarHBondContact O-N 2.99Å; L294-F297 PolarHBondContact O-N 3.23Å; F297-A300 PolarHBondContact O-N 2.93Å; F297-L301 HydrophobicContact CE1-CD2 4.05Å; F297-L301 HydrophobicContact CZ-CD2 4.22Å; F297-L301 WeakPolarHBondContact O-CB 3.49Å; F297-L301 PolarHBondContact O-N 3.4Å
298	V	97.9	Very high	95.9	Very high	36 Å²	36	25.5 Å²	25.5	22%	0.218	13%	0.133	C	C	.	.	H	α-helix	trans	-63.4	-48.7	179.7	174.2	0	0	0	0	110.7	T203 V207 L294 A300 L301 F302	T203-V298 HydrophobicContact CG2-CB 4.08Å; T203-V298 HydrophobicContact CG2-CG1 3.67Å; V207-V298 HydrophobicContact CG2-CG1 3.64Å; L294-V298 HydrophobicContact CD1-CG2 4.19Å; L294-V298 WeakPolarHBondContact O-CB 3.18Å; L294-V298 VanDerWaalsContact O-CG2 3.3Å; L294-V298 WeakPolarHBondContact O-CG2 3.44Å; L294-V298 PolarHBondContact O-N 3.01Å; V298-A300 PolarHBondContact O-N 2.95Å; V298-L301 PolarHBondContact O-N 2.96Å; V298-F302 HydrophobicContact CG1-CD2 3.8Å; V298-F302 HydrophobicContact CG1-CE2 4.06Å; V298-F302 WeakPolarHBondContact O-CD2 3.48Å; V298-F302 PolarHBondContact O-N 3.11Å
299	S	96.8	Very high	95.3	Very high	0 Å²	0	28.8 Å²	28.8	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-61.3	-43	179.1	-64.7	0	0	0	0	112.3	T203 L295 G303	T203-S299 WeakPolarHBondContact CG2-OG 3.46Å; T203-S299 PolarHBondContact OG1-OG 2.93Å; L295-S299 WeakPolarHBondContact O-CB 3.48Å; L295-S299 PolarHBondContact O-N 3.37Å; L295-S299 PolarHBondContact O-OG 3.17Å; S299-G303 WeakPolarHBondContact O-CA 3.5Å; S299-G303 PolarHBondContact O-N 2.85Å
300	A	97.3	Very high	94.9	Very high	0 Å²	0	32.8 Å²	32.8	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-67.9	-41.8	178.5	0	0	0	0	0	111.8	L62 M66 F74 Y296 F297 V298 Y304	L62-A300 HydrophobicContact CB-CB 4.01Å; M66-A300 HydrophobicContact CB-CB 4.5Å; M66-A300 HydrophobicContact CE-CB 3.84Å; F74-A300 HydrophobicContact CE1-CB 3.72Å; F74-A300 HydrophobicContact CE2-CB 4.11Å; F74-A300 HydrophobicContact CZ-CB 3.39Å; Y296-A300 WeakPolarHBondContact O-CB 3.29Å; Y296-A300 PolarHBondContact O-N 3.37Å; F297-A300 PolarHBondContact O-N 2.93Å; V298-A300 PolarHBondContact O-N 2.95Å; A300-Y304 WeakPolarHBondContact O-CB 3.31Å; A300-Y304 PolarHBondContact O-N 3Å
301	L	96.9	Very high	94.6	Very high	32 Å²	32	29.7 Å²	29.7	17%	0.168	15%	0.152	C	C	.	.	H	α-helix	trans	-63	-54.9	179.6	-179	64.1	0	0	0	111.6	M66 I71 F297 V298 Y304 L305	M66-L301 HydrophobicContact CE-CB 4.05Å; M66-L301 HydrophobicContact CE-CD1 4.4Å; M66-L301 VanDerWaalsContact SD-CA 3.57Å; M66-L301 HydrophobicContact SD-CB 4.38Å; M66-L301 HydrophobicContact SD-CD1 4.11Å; I71-L301 HydrophobicContact CD1-CD1 4.18Å; I71-L301 HydrophobicContact CG1-CD1 4.39Å; I71-L301 HydrophobicContact CG2-CD1 4.18Å; F297-L301 HydrophobicContact CE1-CD2 4.05Å; F297-L301 HydrophobicContact CZ-CD2 4.22Å; F297-L301 WeakPolarHBondContact O-CB 3.49Å; F297-L301 PolarHBondContact O-N 3.4Å; V298-L301 PolarHBondContact O-N 2.96Å; L301-Y304 PolarHBondContact O-N 2.83Å; L301-L305 HydrophobicContact CD1-CD1 3.94Å; L301-L305 HydrophobicContact CD1-CG 4.26Å; L301-L305 HydrophobicContact CG-CD1 4Å; L301-L305 WeakPolarHBondContact O-CB 3.35Å; L301-L305 VanDerWaalsContact O-CG 3.22Å; L301-L305 WeakPolarHBondContact O-CG 3.38Å; L301-L305 PolarHBondContact O-N 3.45Å
302	F	96.4	Very high	94.4	Very high	46 Å²	46	31.3 Å²	31.3	20%	0.202	16%	0.159	C	C	.	.	H	α-helix	trans	-72.6	-31.9	-178.4	-73.8	-85.6	0	0	0	112	V206 V207 K210 V298 T306	V206-F302 HydrophobicContact CG1-CB 3.87Å; V207-F302 HydrophobicContact CB-CD1 4.46Å; V207-F302 HydrophobicContact CB-CG 4.34Å; V207-F302 HydrophobicContact CG1-CD1 4.23Å; V207-F302 HydrophobicContact CG1-CE1 4.11Å; V207-F302 HydrophobicContact CG1-CG 4.49Å; V207-F302 HydrophobicContact CG1-CZ 4.25Å; V207-F302 HydrophobicContact CG2-CB 4.27Å; V207-F302 HydrophobicContact CG2-CD1 4.4Å; V207-F302 HydrophobicContact CG2-CD2 3.66Å; V207-F302 HydrophobicContact CG2-CE2 4.05Å; V207-F302 HydrophobicContact CG2-CG 3.85Å; K210-F302 HydrophobicContact CB-CD1 3.91Å; K210-F302 HydrophobicContact CG-CD1 3.95Å; V298-F302 HydrophobicContact CG1-CD2 3.8Å; V298-F302 HydrophobicContact CG1-CE2 4.06Å; V298-F302 WeakPolarHBondContact O-CD2 3.48Å; V298-F302 PolarHBondContact O-N 3.11Å; F302-T306 WeakPolarHBondContact O-CB 3.46Å; F302-T306 PolarHBondContact O-N 3.5Å; F302-T306 VanDerWaalsContact O-N 3.07Å; F302-T306 PolarHBondContact O-OG1 3.24Å
303	G	95.4	Very high	94.1	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-63.2	-44.5	170.8	0	0	0	0	0	112.5	S299 T306	S299-G303 WeakPolarHBondContact O-CA 3.5Å; S299-G303 PolarHBondContact O-N 2.85Å; G303-T306 PolarHBondContact O-N 3.11Å
304	Y	95.3	Very high	93.9	Very high	4 Å²	4	29.2 Å²	29.2	2%	0.016	15%	0.151	C	C	.	.	H	α-helix	trans	-63.8	-50.3	174.5	169.2	-114.7	0	0	0	111.7	M66 A67 I71 P240 K241 A300 L301 T306 F307 Y308 V311	M66-Y304 HydrophobicContact CB-CG 4.47Å; M66-Y304 HydrophobicContact CG-CD1 4.06Å; M66-Y304 HydrophobicContact CG-CG 3.96Å; M66-Y304 HydrophobicContact SD-CD1 3.73Å; M66-Y304 HydrophobicContact SD-CG 3.89Å; A67-Y304 HydrophobicContact CB-CD2 3.74Å; A67-Y304 HydrophobicContact CB-CE2 4.03Å; I71-Y304 HydrophobicContact CD1-CD1 4.29Å; I71-Y304 HydrophobicContact CD1-CE1 3.97Å; I71-Y304 HydrophobicContact CG1-CD1 3.92Å; I71-Y304 HydrophobicContact CG1-CE1 3.68Å; P240-Y304 HydrophobicContact CB-CE1 4.4Å; K241-Y304 PolarHBondContact N-OH 2.6Å; A300-Y304 WeakPolarHBondContact O-CB 3.31Å; A300-Y304 PolarHBondContact O-N 3Å; L301-Y304 PolarHBondContact O-N 2.83Å; Y304-T306 PolarHBondContact O-N 3.24Å; Y304-T306 VanDerWaalsContact O-N 3.08Å; Y304-F307 PolarHBondContact O-N 3.23Å; Y304-F307 VanDerWaalsContact O-N 3.16Å; Y304-Y308 WeakPolarHBondContact CE2-O 3.2Å; Y304-Y308 WeakPolarHBondContact O-CA 3.5Å; Y304-Y308 PolarHBondContact O-N 2.98Å; Y304-V311 HydrophobicContact CD2-CG2 4.25Å
305	L	93.4	Very high	93.7	Very high	33 Å²	33	24.8 Å²	24.8	17%	0.173	13%	0.127	C	C	.	.	H	α-helix	trans	-64.5	-15.1	-179.9	-69.4	175.7	0	0	0	113.2	I71 K210 P240 L301 Y308	I71-L305 HydrophobicContact CD1-CD2 4.36Å; K210-L305 HydrophobicContact CD-CB 3.61Å; K210-L305 WeakPolarHBondContact CD-O 3.33Å; K210-L305 WeakPolarHBondContact CE-O 3.43Å; K210-L305 PolarHBondContact NZ-O 3.1Å; P240-L305 HydrophobicContact CB-CD2 4.08Å; L301-L305 HydrophobicContact CD1-CD1 3.94Å; L301-L305 HydrophobicContact CD1-CG 4.26Å; L301-L305 HydrophobicContact CG-CD1 4Å; L301-L305 WeakPolarHBondContact O-CB 3.35Å; L301-L305 VanDerWaalsContact O-CG 3.22Å; L301-L305 WeakPolarHBondContact O-CG 3.38Å; L301-L305 PolarHBondContact O-N 3.45Å; L305-Y308 HydrophobicContact CD2-CE1 4.24Å; L305-Y308 WeakPolarHBondContact O-CE2 3.49Å
306	T	92.1	Very high	93.4	Very high	3 Å²	3	24.4 Å²	24.4	2%	0.018	13%	0.126	C	C	.	.	H	α-helix	trans	-78.5	-39.2	175.3	-60.6	0	0	0	0	112	K210 I213 F302 G303 Y304 Y319	K210-T306 WeakPolarHBondContact CA-OG1 3.42Å; I213-T306 HydrophobicContact CB-CG2 4.2Å; I213-T306 HydrophobicContact CD1-CG2 3.75Å; I213-T306 HydrophobicContact CG2-CG2 4.38Å; F302-T306 WeakPolarHBondContact O-CB 3.46Å; F302-T306 PolarHBondContact O-N 3.5Å; F302-T306 VanDerWaalsContact O-N 3.07Å; F302-T306 PolarHBondContact O-OG1 3.24Å; G303-T306 PolarHBondContact O-N 3.11Å; Y304-T306 PolarHBondContact O-N 3.24Å; Y304-T306 VanDerWaalsContact O-N 3.08Å; T306-Y319 HydrophobicContact CG2-CE1 4Å
307	F	90.4	Very high	93	Very high	1 Å²	1	26.9 Å²	26.9	0%	0.004	14%	0.139	C	C	.	.	H	α-helix	trans	-119.7	-7.9	-172.8	-55.7	-68.5	0	0	0	115	I213 L217 Y304 S309 H310 V311 L315 Y319 Y322	I213-F307 HydrophobicContact CD1-CE1 4.48Å; I213-F307 HydrophobicContact CD1-CZ 4.45Å; L217-F307 HydrophobicContact CD1-CD1 4.46Å; L217-F307 HydrophobicContact CD2-CD1 3.89Å; L217-F307 HydrophobicContact CD2-CE1 4.31Å; Y304-F307 PolarHBondContact O-N 3.23Å; Y304-F307 VanDerWaalsContact O-N 3.16Å; F307-S309 PolarHBondContact O-N 3.04Å; F307-H310 PolarHBondContact O-N 2.9Å; F307-V311 HydrophobicContact CB-CG2 3.8Å; F307-L315 HydrophobicContact CD2-CD1 3.98Å; F307-L315 HydrophobicContact CE2-CD1 3.85Å; F307-Y319 HydrophobicContact CE2-CD1 4.29Å; F307-Y319 HydrophobicContact CE2-CD2 4.26Å; F307-Y319 HydrophobicContact CE2-CE1 4.07Å; F307-Y319 HydrophobicContact CE2-CE2 4.08Å; F307-Y319 HydrophobicContact CE2-CG 4.37Å; F307-Y319 AromaticContact CE2-CZ 3.98Å; F307-Y319 AromaticContact CZ-CD1 3.74Å; F307-Y319 HydrophobicContact CZ-CD1 3.74Å; F307-Y319 HydrophobicContact CZ-CD2 4.39Å; F307-Y319 AromaticContact CZ-CE1 3.82Å; F307-Y319 HydrophobicContact CZ-CE1 3.82Å; F307-Y319 HydrophobicContact CZ-CE2 4.48Å; F307-Y319 HydrophobicContact CZ-CG 4.03Å; F307-Y322 AromaticContact CD1-CD2 3.87Å; F307-Y322 HydrophobicContact CD1-CD2 3.87Å; F307-Y322 AromaticContact CD1-CE2 3.8Å; F307-Y322 HydrophobicContact CD1-CE2 3.8Å; F307-Y322 AromaticContact CE1-CD2 3.4Å; F307-Y322 HydrophobicContact CE1-CD2 3.4Å; F307-Y322 VanDerWaalsContact CE1-CD2 3.4Å; F307-Y322 AromaticContact CE1-CE2 3.83Å; F307-Y322 HydrophobicContact CE1-CE2 3.83Å; F307-Y322 HydrophobicContact CE1-CG 4.32Å; F307-Y322 HydrophobicContact CZ-CD2 4.39Å
308	Y	90.4	Very high	92.6	Very high	28 Å²	28	24.3 Å²	24.3	11%	0.11	13%	0.127	C	C	.	.	G	3₁₀ helix	trans	48.3	-113.4	-178.7	-63	-92.5	0	0	0	113.3	C215 E237 C238 P240 Y304 L305 H310 V311	C215-Y308 HydrophobicContact CB-CE2 4.07Å; C215-Y308 VanDerWaalsContact SG-CE2 3.52Å; E237-Y308 VanDerWaalsContact O-CB 3.3Å; E237-Y308 WeakPolarHBondContact O-CB 3.17Å; C238-Y308 VanDerWaalsContact C-CE1 3.46Å; C238-Y308 HydrophobicContact CB-CE2 4.34Å; C238-Y308 WeakPolarHBondContact O-CE1 3.2Å; C238-Y308 VanDerWaalsContact O-CZ 3.22Å; C238-Y308 PolarHBondContact O-OH 3.47Å; P240-Y308 HydrophobicContact CB-CE1 4.46Å; Y304-Y308 WeakPolarHBondContact CE2-O 3.2Å; Y304-Y308 WeakPolarHBondContact O-CA 3.5Å; Y304-Y308 PolarHBondContact O-N 2.98Å; L305-Y308 HydrophobicContact CD2-CE1 4.24Å; L305-Y308 WeakPolarHBondContact O-CE2 3.49Å; Y308-H310 PolarHBondContact O-N 3.26Å; Y308-V311 WeakPolarHBondContact O-CG2 3.14Å
309	S	85	Confident	92.1	Very high	70 Å²	70	23 Å²	23	49%	0.49	12%	0.119	S	C	.	.	G	3₁₀ helix	trans	-71.5	-13.6	179	41.9	0	0	0	0	114.4	F307	F307-S309 PolarHBondContact O-N 3.04Å
310	H	88.3	Confident	91.4	Very high	86 Å²	86	23.6 Å²	23.6	40%	0.398	13%	0.125	S	C	.	.	G	3₁₀ helix	trans	-104.5	21.4	-173.2	-60.2	-79	0	0	0	113.5	L217 F307 Y308 Q312	L217-H310 HydrophobicContact CD1-CB 4.2Å; F307-H310 PolarHBondContact O-N 2.9Å; Y308-H310 PolarHBondContact O-N 3.26Å; H310-Q312 PolarHBondContact O-N 2.7Å
311	V	90.9	Very high	90.7	Very high	11 Å²	11	27.9 Å²	27.9	7%	0.067	15%	0.151	C	C	.	.			trans	-64.9	124.9	174	-178.6	0	0	0	0	109.7	A63 A67 Y304 F307 Y308	A63-V311 HydrophobicContact CB-CG1 3.9Å; A67-V311 HydrophobicContact CB-CB 3.85Å; A67-V311 HydrophobicContact CB-CG2 3.88Å; Y304-V311 HydrophobicContact CD2-CG2 4.25Å; F307-V311 HydrophobicContact CB-CG2 3.8Å; Y308-V311 WeakPolarHBondContact O-CG2 3.14Å
312	Q	92.3	Very high	89.9	Confident	90 Å²	90	29.5 Å²	29.5	42%	0.421	16%	0.155	S	C	.	.			trans	-73.4	160.5	174.3	-65.8	-60.6	-24.9	0	0	111.4	Y64 H310 E314 L317	Y64-Q312 WeakPolarHBondContact CB-O 3.38Å; H310-Q312 PolarHBondContact O-N 2.7Å; Q312-E314 WeakPolarHBondContact CB-O 3.24Å; Q312-E314 PolarHBondContact O-N 3.32Å; Q312-L317 HydrophobicContact CB-CB 4.38Å
313	S	90.7	Very high	89.2	Confident	12 Å²	12	31.5 Å²	31.5	8%	0.084	16%	0.162	C	C	.	.	S	Bend	trans	-52.7	-33.6	174.1	40.3	0	0	0	0	114	G61 D390 R392	G61-S313 WeakPolarHBondContact CA-O 3.37Å; S313-D390 WeakPolarHBondContact CB-OD1 3.22Å; S313-D390 PolarHBondContact OG-OD1 3.4Å; S313-R392 VanDerWaalsContact CB-CD 3.44Å
314	E	92.7	Very high	88.2	Confident	0 Å²	0	34.3 Å²	34.3	0%	0	18%	0.18	C	C	.	.	S	Bend	trans	-118.8	122.7	174	179.7	178.7	-176.2	0	0	108.5	L60 S141 E142 Q312 L316 L317 I391	L60-E314 HydrophobicContact CB-CG 4.2Å; L60-E314 HydrophobicContact CD1-CG 4.23Å; S141-E314 PolarHBondContact OG-OE2 3.45Å; E142-E314 WeakPolarHBondContact CG-OE1 3.5Å; Q312-E314 WeakPolarHBondContact CB-O 3.24Å; Q312-E314 PolarHBondContact O-N 3.32Å; E314-L316 VanDerWaalsContact C-N 3.3Å; E314-L316 PolarHBondContact O-N 2.67Å; E314-L317 HydrophobicContact CB-CD1 3.86Å; E314-L317 HydrophobicContact CB-CG 4.01Å; E314-L317 HydrophobicContact CG-CD1 4.49Å; E314-L317 HydrophobicContact CG-CG 4.2Å; E314-L317 PolarHBondContact O-N 2.92Å; E314-I391 HydrophobicContact CB-CG2 4.33Å
315	L	93.1	Very high	87.3	Confident	2 Å²	2	41 Å²	41	1%	0.01	21%	0.211	C	C	.	.	H	α-helix	trans	-61.3	-35.3	-173.9	-175.1	62	0	0	0	113.6	L60 A63 F202 V206 F307 L317 G318 Y319	L60-L315 PolarHBondContact O-N 3.44Å; A63-L315 HydrophobicContact CB-CD1 3.89Å; A63-L315 HydrophobicContact CB-CD2 4.23Å; A63-L315 HydrophobicContact CB-CG 4.44Å; F202-L315 HydrophobicContact CE2-CD2 4.37Å; F202-L315 HydrophobicContact CZ-CD2 3.8Å; V206-L315 HydrophobicContact CG1-CD2 4.22Å; V206-L315 HydrophobicContact CG2-CD2 3.87Å; F307-L315 HydrophobicContact CD2-CD1 3.98Å; F307-L315 HydrophobicContact CE2-CD1 3.85Å; L315-L317 PolarHBondContact O-N 3.49Å; L315-G318 PolarHBondContact O-N 3.26Å; L315-Y319 HydrophobicContact CD1-CE2 4.09Å; L315-Y319 HydrophobicContact CD2-CE2 4.1Å; L315-Y319 HydrophobicContact CG-CD2 4.23Å; L315-Y319 HydrophobicContact CG-CE2 3.77Å; L315-Y319 WeakPolarHBondContact O-CD2 3.23Å; L315-Y319 PolarHBondContact O-N 3.32Å
316	L	91.2	Very high	87	Confident	3 Å²	3	40.7 Å²	40.7	2%	0.016	21%	0.209	C	C	.	.	H	α-helix	trans	-66.9	-33.9	-179.4	-80.7	136.1	0	0	0	113.3	L60 E142 F202 E314 G318 Y319 G320 V332 R333 I336	L60-L316 HydrophobicContact CD1-CD1 3.79Å; L60-L316 HydrophobicContact CD2-CD1 3.34Å; L60-L316 HydrophobicContact CD2-CG 4.26Å; L60-L316 HydrophobicContact CG-CD1 4.21Å; E142-L316 HydrophobicContact CG-CB 4.3Å; E142-L316 VanDerWaalsContact OE1-CB 3.25Å; E142-L316 WeakPolarHBondContact OE1-CB 3.48Å; F202-L316 HydrophobicContact CE2-CD1 4.34Å; F202-L316 HydrophobicContact CE2-CG 4.38Å; E314-L316 VanDerWaalsContact C-N 3.3Å; E314-L316 PolarHBondContact O-N 2.67Å; L316-G318 PolarHBondContact O-N 3.38Å; L316-Y319 PolarHBondContact O-N 3.26Å; L316-Y319 VanDerWaalsContact O-N 3.14Å; L316-G320 PolarHBondContact O-N 2.88Å; L316-V332 HydrophobicContact CD2-CG1 4.17Å; L316-R333 HydrophobicContact CD2-CG 3.63Å; L316-I336 HydrophobicContact CD1-CD1 3.53Å; L316-I336 HydrophobicContact CD1-CG2 4.36Å; L316-I336 HydrophobicContact CD2-CD1 4.5Å
317	L	89.8	Confident	86.8	Confident	52 Å²	52	50.7 Å²	50.7	27%	0.272	25%	0.247	S	C	.	.	H	α-helix	trans	-59.3	-40.2	173.7	-68.3	178.7	0	0	0	111	E142 Q312 E314 L315 G320 V321	E142-L317 WeakPolarHBondContact OE1-CD2 3.42Å; E142-L317 PolarHBondContact OE1-N 3.19Å; Q312-L317 HydrophobicContact CB-CB 4.38Å; E314-L317 HydrophobicContact CB-CD1 3.86Å; E314-L317 HydrophobicContact CB-CG 4.01Å; E314-L317 HydrophobicContact CG-CD1 4.49Å; E314-L317 HydrophobicContact CG-CG 4.2Å; E314-L317 PolarHBondContact O-N 2.92Å; L315-L317 PolarHBondContact O-N 3.49Å; L317-G320 PolarHBondContact O-N 3.03Å; L317-V321 WeakPolarHBondContact O-CG2 3.49Å; L317-V321 PolarHBondContact O-N 3.38Å; L317-V321 VanDerWaalsContact O-N 3.09Å
318	G	87.5	Confident	86.8	Confident	1 Å²	1	54.8 Å²	54.8	1%	0.01	27%	0.267	C	S	.	.	H	α-helix	trans	-56.7	-51.1	173.5	0	0	0	0	0	111.9	L315 L316 G320 V321 Y322	L315-G318 PolarHBondContact O-N 3.26Å; L316-G318 PolarHBondContact O-N 3.38Å; G318-G320 VanDerWaalsContact C-N 3.3Å; G318-G320 PolarHBondContact O-N 3.23Å; G318-V321 PolarHBondContact O-N 2.9Å; G318-Y322 VanDerWaalsContact O-CD2 3.23Å; G318-Y322 WeakPolarHBondContact O-CD2 3.49Å; G318-Y322 PolarHBondContact O-N 2.9Å
319	Y	88.8	Confident	86.8	Confident	8 Å²	8	53.7 Å²	53.7	3%	0.031	26%	0.263	C	S	.	.	H	α-helix	trans	-62.3	-36.2	177.2	-72.6	-67.4	0	0	0	113.2	V206 K209 I213 T306 F307 L315 L316 V321 R323	V206-Y319 HydrophobicContact CG2-CE2 4.08Å; K209-Y319 HydrophobicContact CB-CD1 4.33Å; K209-Y319 HydrophobicContact CB-CE1 3.47Å; K209-Y319 VanDerWaalsContact CB-CE1 3.47Å; K209-Y319 HydrophobicContact CG-CD1 4.43Å; K209-Y319 HydrophobicContact CG-CE1 3.97Å; I213-Y319 HydrophobicContact CD1-CD1 3.82Å; I213-Y319 HydrophobicContact CD1-CE1 3.7Å; T306-Y319 HydrophobicContact CG2-CE1 4Å; F307-Y319 HydrophobicContact CE2-CD1 4.29Å; F307-Y319 HydrophobicContact CE2-CD2 4.26Å; F307-Y319 HydrophobicContact CE2-CE1 4.07Å; F307-Y319 HydrophobicContact CE2-CE2 4.08Å; F307-Y319 HydrophobicContact CE2-CG 4.37Å; F307-Y319 AromaticContact CE2-CZ 3.98Å; F307-Y319 AromaticContact CZ-CD1 3.74Å; F307-Y319 HydrophobicContact CZ-CD1 3.74Å; F307-Y319 HydrophobicContact CZ-CD2 4.39Å; F307-Y319 AromaticContact CZ-CE1 3.82Å; F307-Y319 HydrophobicContact CZ-CE1 3.82Å; F307-Y319 HydrophobicContact CZ-CE2 4.48Å; F307-Y319 HydrophobicContact CZ-CG 4.03Å; L315-Y319 HydrophobicContact CD1-CE2 4.09Å; L315-Y319 HydrophobicContact CD2-CE2 4.1Å; L315-Y319 HydrophobicContact CG-CD2 4.23Å; L315-Y319 HydrophobicContact CG-CE2 3.77Å; L315-Y319 WeakPolarHBondContact O-CD2 3.23Å; L315-Y319 PolarHBondContact O-N 3.32Å; L316-Y319 PolarHBondContact O-N 3.26Å; L316-Y319 VanDerWaalsContact O-N 3.14Å; Y319-V321 VanDerWaalsContact C-N 3.35Å; Y319-V321 PolarHBondContact O-N 3.49Å; Y319-R323 CarbonylContact O-C 3.37Å; Y319-R323 WeakPolarHBondContact O-CA 3.21Å; Y319-R323 PolarHBondContact O-N 3.46Å
320	G	82.3	Confident	87	Confident	13 Å²	13	51.5 Å²	51.5	13%	0.134	25%	0.246	C	C	.	.	H	α-helix	trans	-61.6	-38.9	176.3	0	0	0	0	0	114	L316 L317 G318 P324	L316-G320 PolarHBondContact O-N 2.88Å; L317-G320 PolarHBondContact O-N 3.03Å; G318-G320 VanDerWaalsContact C-N 3.3Å; G318-G320 PolarHBondContact O-N 3.23Å; G320-P324 WeakPolarHBondContact O-CA 2.95Å; G320-P324 WeakPolarHBondContact O-CB 3.43Å
321	V	82.3	Confident	87.3	Confident	91 Å²	91	50.3 Å²	50.3	55%	0.552	25%	0.245	S	C	*	.	H	α-helix	trans	-69.2	-44.8	-179.7	171.8	0	0	0	0	111.5	L317 G318 Y319	L317-V321 WeakPolarHBondContact O-CG2 3.49Å; L317-V321 PolarHBondContact O-N 3.38Å; L317-V321 VanDerWaalsContact O-N 3.09Å; G318-V321 PolarHBondContact O-N 2.9Å; Y319-V321 VanDerWaalsContact C-N 3.35Å; Y319-V321 PolarHBondContact O-N 3.49Å
322	Y	80.2	Confident	87.4	Confident	65 Å²	65	50 Å²	50	26%	0.255	24%	0.243	S	C	.	.	H	α-helix	trans	-91.6	-23.3	-174	-63.5	-75.2	0	0	0	114.2	L217 F307 G318	L217-Y322 HydrophobicContact CB-CD1 4.45Å; L217-Y322 HydrophobicContact CB-CE1 3.86Å; L217-Y322 HydrophobicContact CD1-CE1 4.38Å; L217-Y322 HydrophobicContact CD1-CE2 4.36Å; L217-Y322 HydrophobicContact CD2-CD1 4.17Å; L217-Y322 HydrophobicContact CD2-CD2 4.28Å; L217-Y322 HydrophobicContact CD2-CE1 4.05Å; L217-Y322 HydrophobicContact CD2-CE2 4.17Å; L217-Y322 HydrophobicContact CD2-CG 4.29Å; L217-Y322 HydrophobicContact CG-CE1 4.31Å; F307-Y322 AromaticContact CD1-CD2 3.87Å; F307-Y322 HydrophobicContact CD1-CD2 3.87Å; F307-Y322 AromaticContact CD1-CE2 3.8Å; F307-Y322 HydrophobicContact CD1-CE2 3.8Å; F307-Y322 AromaticContact CE1-CD2 3.4Å; F307-Y322 HydrophobicContact CE1-CD2 3.4Å; F307-Y322 VanDerWaalsContact CE1-CD2 3.4Å; F307-Y322 AromaticContact CE1-CE2 3.83Å; F307-Y322 HydrophobicContact CE1-CE2 3.83Å; F307-Y322 HydrophobicContact CE1-CG 4.32Å; F307-Y322 HydrophobicContact CZ-CD2 4.39Å; G318-Y322 VanDerWaalsContact O-CD2 3.23Å; G318-Y322 WeakPolarHBondContact O-CD2 3.49Å; G318-Y322 PolarHBondContact O-N 2.9Å
323	R	80.4	Confident	87.4	Confident	89 Å²	89	46.3 Å²	46.3	34%	0.336	23%	0.225	S	C	.	.			trans	-142.3	62.4	-175.9	-75.7	-65.4	-171.3	100.2	0.2	111.9	S212 I213 Y319 H325 D326	S212-R323 PolarHBondContact O-NH2 3.11Å; I213-R323 HydrophobicContact CD1-CG 4.39Å; I213-R323 HydrophobicContact CG1-CG 4.38Å; Y319-R323 CarbonylContact O-C 3.37Å; Y319-R323 WeakPolarHBondContact O-CA 3.21Å; Y319-R323 PolarHBondContact O-N 3.46Å; R323-H325 VanDerWaalsContact C-N 3.28Å; R323-H325 PolarHBondContact O-N 3.16Å; R323-D326 HydrophobicContact CB-CB 3.98Å; R323-D326 IonicContact NH1-OD2 3.23Å; R323-D326 PolarHBondContact NH1-OD2 3.05Å; R323-D326 PolarHBondContact O-N 2.92Å
324	P	74.8	Confident	87.5	Confident	58 Å²	58	49.6 Å²	49.6	38%	0.377	24%	0.241	S	C	.	.	T	Hydrogen-bonded Turn	trans	-64.1	-27.5	-174.4	24.9	-34.6	0	0	0	114.3	S149 G320	S149-P324 PolarHBondContact OG-O 3.12Å; G320-P324 WeakPolarHBondContact O-CA 2.95Å; G320-P324 WeakPolarHBondContact O-CB 3.43Å
325	H	77.4	Confident	87.6	Confident	146 Å²	146	50 Å²	50	68%	0.676	25%	0.245	S	C	*	.	T	Hydrogen-bonded Turn	trans	-110.5	14.7	-173.7	-57.4	-10.1	0	0	0	113.5	R323 R327	R323-H325 VanDerWaalsContact C-N 3.28Å; R323-H325 PolarHBondContact O-N 3.16Å; H325-R327 PolarHBondContact O-N 3.14Å
326	D	85.9	Confident	87.6	Confident	26 Å²	26	50.2 Å²	50.2	14%	0.139	25%	0.246	C	C	.	.			trans	-77.8	116.9	-179.2	-168.9	-49.6	0	0	0	110.6	K209 R323 M328 V329 I330	K209-D326 IonicContact NZ-OD1 3.59Å; K209-D326 PolarHBondContact NZ-OD1 2.9Å; K209-D326 IonicContact NZ-OD2 2.65Å; K209-D326 PolarHBondContact NZ-OD2 3.22Å; R323-D326 HydrophobicContact CB-CB 3.98Å; R323-D326 IonicContact NH1-OD2 3.23Å; R323-D326 PolarHBondContact NH1-OD2 3.05Å; R323-D326 PolarHBondContact O-N 2.92Å; D326-M328 PolarHBondContact O-N 3.38Å; D326-M328 VanDerWaalsContact O-N 3.09Å; D326-M328 PolarHBondContact OD1-N 3.48Å; D326-M328 VanDerWaalsContact OD1-N 3.11Å; D326-V329 HydrophobicContact CB-CB 4.27Å; D326-V329 HydrophobicContact CB-CG2 3.92Å; D326-V329 PolarHBondContact O-N 3.35Å; D326-I330 WeakPolarHBondContact O-CG1 3.15Å; D326-I330 PolarHBondContact O-N 3.46Å
327	R	89	Confident	87.7	Confident	212 Å²	212	50.5 Å²	50.5	80%	0.8	25%	0.247	S	C	*	.	H	α-helix	trans	-50.2	-38.8	-176.7	-67.4	-170.9	-69	-172.6	-2	113.5	H325 T331	H325-R327 PolarHBondContact O-N 3.14Å; R327-T331 WeakPolarHBondContact O-CG2 3.38Å; R327-T331 PolarHBondContact O-N 2.98Å; R327-T331 PolarHBondContact O-OG1 3.12Å; R327-T331 VanDerWaalsContact O-OG1 3.11Å
328	M	90.1	Very high	87.9	Confident	88 Å²	88	51.5 Å²	51.5	43%	0.433	25%	0.253	S	S	.	.	H	α-helix	trans	-71	-33.4	179.4	-65.6	180	175.9	0	0	112.6	V205 V208 D326 T331 V332	V205-M328 HydrophobicContact CG1-CB 4.15Å; V208-M328 HydrophobicContact CG1-SD 4.16Å; D326-M328 PolarHBondContact O-N 3.38Å; D326-M328 VanDerWaalsContact O-N 3.09Å; D326-M328 PolarHBondContact OD1-N 3.48Å; D326-M328 VanDerWaalsContact OD1-N 3.11Å; M328-T331 WeakPolarHBondContact CA-OG1 3.43Å; M328-T331 PolarHBondContact O-OG1 2.94Å; M328-V332 VanDerWaalsContact O-CG2 3.24Å; M328-V332 WeakPolarHBondContact O-CG2 3.25Å; M328-V332 PolarHBondContact O-N 3.35Å
329	V	89.6	Confident	88.1	Confident	5 Å²	5	51.8 Å²	51.8	3%	0.03	25%	0.254	C	S	.	.	H	α-helix	trans	-71.5	-41	177.6	179.2	0	0	0	0	109.6	K209 D326 V332 R333	K209-V329 HydrophobicContact CD-CG2 4.39Å; D326-V329 HydrophobicContact CB-CB 4.27Å; D326-V329 HydrophobicContact CB-CG2 3.92Å; D326-V329 PolarHBondContact O-N 3.35Å; V329-V332 PolarHBondContact O-N 3.04Å; V329-R333 WeakPolarHBondContact O-CG 3.33Å; V329-R333 PolarHBondContact O-N 2.85Å
330	I	90.9	Very high	88.2	Confident	23 Å²	23	51.7 Å²	51.7	12%	0.118	25%	0.254	C	S	.	.	H	α-helix	trans	-61.4	-46.6	176.8	-59.2	162.2	0	0	0	110.9	S149 D326 V332 R333 L334	S149-I330 WeakPolarHBondContact OG-CD1 3.38Å; S149-I330 WeakPolarHBondContact OG-CG1 3.33Å; D326-I330 WeakPolarHBondContact O-CG1 3.15Å; D326-I330 PolarHBondContact O-N 3.46Å; I330-V332 VanDerWaalsContact C-N 3.34Å; I330-V332 PolarHBondContact O-N 3.25Å; I330-R333 WeakPolarHBondContact O-CB 3.41Å; I330-R333 PolarHBondContact O-N 3.06Å; I330-L334 HydrophobicContact CG2-CD1 4.38Å; I330-L334 WeakPolarHBondContact O-CG 3.28Å; I330-L334 PolarHBondContact O-N 3Å
331	T	92.7	Very high	88.6	Confident	62 Å²	62	52.7 Å²	52.7	38%	0.38	26%	0.256	S	S	.	.	H	α-helix	trans	-64	-38.5	178.9	49.7	0	0	0	0	112.3	Y201 R327 M328 L334 A335	Y201-T331 PolarHBondContact OH-OG1 3.42Å; R327-T331 WeakPolarHBondContact O-CG2 3.38Å; R327-T331 PolarHBondContact O-N 2.98Å; R327-T331 PolarHBondContact O-OG1 3.12Å; R327-T331 VanDerWaalsContact O-OG1 3.11Å; M328-T331 WeakPolarHBondContact CA-OG1 3.43Å; M328-T331 PolarHBondContact O-OG1 2.94Å; T331-L334 PolarHBondContact O-N 3.31Å; T331-A335 WeakPolarHBondContact O-CB 3.28Å; T331-A335 PolarHBondContact O-N 3.06Å
332	V	93.4	Very high	88.9	Confident	5 Å²	5	50.2 Å²	50.2	3%	0.03	24%	0.24	C	C	.	.	H	α-helix	trans	-66.5	-40.4	175.2	169.9	0	0	0	0	112.1	Y201 F202 V205 L316 M328 V329 I330 L334 A335 I336	Y201-V332 HydrophobicContact CD1-CG2 3.75Å; Y201-V332 HydrophobicContact CE1-CB 4.25Å; Y201-V332 HydrophobicContact CE1-CG2 3.33Å; F202-V332 HydrophobicContact CB-CG1 4.05Å; F202-V332 HydrophobicContact CD2-CG1 3.6Å; F202-V332 HydrophobicContact CG-CG1 4.31Å; V205-V332 HydrophobicContact CB-CG2 3.57Å; V205-V332 HydrophobicContact CG1-CG2 3.75Å; V205-V332 HydrophobicContact CG2-CG2 3.44Å; V205-V332 VanDerWaalsContact CG2-CG2 3.44Å; L316-V332 HydrophobicContact CD2-CG1 4.17Å; M328-V332 VanDerWaalsContact O-CG2 3.24Å; M328-V332 WeakPolarHBondContact O-CG2 3.25Å; M328-V332 PolarHBondContact O-N 3.35Å; V329-V332 PolarHBondContact O-N 3.04Å; I330-V332 VanDerWaalsContact C-N 3.34Å; I330-V332 PolarHBondContact O-N 3.25Å; V332-L334 PolarHBondContact O-N 2.94Å; V332-A335 PolarHBondContact O-N 3.4Å; V332-I336 HydrophobicContact CG1-CD1 3.96Å; V332-I336 PolarHBondContact O-N 2.99Å
333	R	92.5	Very high	89.3	Confident	12 Å²	12	47.3 Å²	47.3	5%	0.045	23%	0.229	C	C	.	.	H	α-helix	trans	-55.4	-52.2	173.3	-78.4	171.1	159.4	-176.3	-12.2	110.9	E142 A146 L316 V329 I330 A335 I336 L337	E142-R333 IonicContact OE2-CZ 3.04Å; E142-R333 VanDerWaalsContact OE2-CZ 3.23Å; E142-R333 IonicContact OE2-NE 2.68Å; E142-R333 PolarHBondContact OE2-NE 2.88Å; E142-R333 IonicContact OE2-NH2 2.7Å; E142-R333 PolarHBondContact OE2-NH2 2.86Å; A146-R333 HydrophobicContact CB-CB 4.5Å; L316-R333 HydrophobicContact CD2-CG 3.63Å; V329-R333 WeakPolarHBondContact O-CG 3.33Å; V329-R333 PolarHBondContact O-N 2.85Å; I330-R333 WeakPolarHBondContact O-CB 3.41Å; I330-R333 PolarHBondContact O-N 3.06Å; R333-A335 VanDerWaalsContact C-N 3.32Å; R333-A335 PolarHBondContact O-N 2.95Å; R333-I336 PolarHBondContact O-N 3.47Å; R333-L337 WeakPolarHBondContact O-CB 3.21Å; R333-L337 WeakPolarHBondContact O-CG 3.28Å; R333-L337 PolarHBondContact O-N 2.96Å
334	L	93.5	Very high	89.8	Confident	81 Å²	81	43 Å²	43	42%	0.424	21%	0.213	S	C	.	.	H	α-helix	trans	-60.2	-41.5	178.5	-66.4	174	0	0	0	112.1	A146 I330 T331 V332 L337 L338	A146-L334 HydrophobicContact CB-CD2 4.05Å; I330-L334 HydrophobicContact CG2-CD1 4.38Å; I330-L334 WeakPolarHBondContact O-CG 3.28Å; I330-L334 PolarHBondContact O-N 3Å; T331-L334 PolarHBondContact O-N 3.31Å; V332-L334 PolarHBondContact O-N 2.94Å; L334-L337 PolarHBondContact O-N 3.11Å; L334-L338 WeakPolarHBondContact O-CB 3.43Å; L334-L338 PolarHBondContact O-N 3.45Å
335	A	93.9	Very high	90.5	Very high	9 Å²	9	41.1 Å²	41.1	7%	0.074	20%	0.2	C	C	.	.	H	α-helix	trans	-62.5	-43.6	177.3	0	0	0	0	0	112.5	F198 Y201 T331 V332 R333 L338 S339	F198-A335 HydrophobicContact CB-CB 4.07Å; F198-A335 HydrophobicContact CD1-CB 3.69Å; F198-A335 VanDerWaalsContact CD2-O 3.29Å; F198-A335 WeakPolarHBondContact CD2-O 3.35Å; F198-A335 HydrophobicContact CE1-CB 4.27Å; F198-A335 HydrophobicContact CG-CB 3.89Å; Y201-A335 HydrophobicContact CD1-CB 4.22Å; T331-A335 WeakPolarHBondContact O-CB 3.28Å; T331-A335 PolarHBondContact O-N 3.06Å; V332-A335 PolarHBondContact O-N 3.4Å; R333-A335 VanDerWaalsContact C-N 3.32Å; R333-A335 PolarHBondContact O-N 2.95Å; A335-L338 PolarHBondContact O-N 3.46Å; A335-S339 WeakPolarHBondContact O-CB 3.45Å; A335-S339 PolarHBondContact O-N 2.66Å
336	I	93.3	Very high	90.8	Very high	6 Å²	6	35.8 Å²	35.8	3%	0.031	18%	0.177	C	C	.	.	H	α-helix	trans	-70.1	-43.5	177.8	-72.3	176.2	0	0	0	111.1	L60 I138 F202 L316 V332 R333 L338 S339 V340	L60-I336 HydrophobicContact CD1-CG2 4.48Å; L60-I336 HydrophobicContact CD2-CD1 4.23Å; I138-I336 HydrophobicContact CG2-CG2 4.17Å; F202-I336 HydrophobicContact CB-CD1 3.99Å; F202-I336 HydrophobicContact CD2-CD1 3.37Å; F202-I336 HydrophobicContact CE2-CD1 3.96Å; F202-I336 HydrophobicContact CG-CD1 3.79Å; L316-I336 HydrophobicContact CD1-CD1 3.53Å; L316-I336 HydrophobicContact CD1-CG2 4.36Å; L316-I336 HydrophobicContact CD2-CD1 4.5Å; V332-I336 HydrophobicContact CG1-CD1 3.96Å; V332-I336 PolarHBondContact O-N 2.99Å; R333-I336 PolarHBondContact O-N 3.47Å; I336-L338 VanDerWaalsContact C-N 3.28Å; I336-L338 PolarHBondContact O-N 3.15Å; I336-S339 WeakPolarHBondContact O-CB 3.42Å; I336-S339 PolarHBondContact O-N 3.06Å; I336-V340 HydrophobicContact CG2-CG2 4.16Å; I336-V340 WeakPolarHBondContact O-CB 3.34Å; I336-V340 VanDerWaalsContact O-CG2 3.25Å; I336-V340 WeakPolarHBondContact O-CG2 2.77Å; I336-V340 PolarHBondContact O-N 2.79Å
337	L	94.2	Very high	91	Very high	8 Å²	8	35.7 Å²	35.7	4%	0.042	18%	0.176	C	C	.	.	H	α-helix	trans	-56	-45.4	175	-70.4	169.6	0	0	0	110.6	L139 E142 L143 A146 R333 L334 V340 L341	L139-L337 HydrophobicContact CD2-CB 4.41Å; L139-L337 HydrophobicContact CD2-CD2 3.55Å; E142-L337 HydrophobicContact CB-CD2 4.02Å; E142-L337 HydrophobicContact CB-CG 4.48Å; L143-L337 HydrophobicContact CB-CD1 4.43Å; L143-L337 HydrophobicContact CB-CD2 4.24Å; L143-L337 HydrophobicContact CD1-CD1 4.09Å; A146-L337 HydrophobicContact CB-CD1 3.86Å; R333-L337 WeakPolarHBondContact O-CB 3.21Å; R333-L337 WeakPolarHBondContact O-CG 3.28Å; R333-L337 PolarHBondContact O-N 2.96Å; L334-L337 PolarHBondContact O-N 3.11Å; L337-V340 PolarHBondContact O-N 2.94Å; L337-L341 VanDerWaalsContact O-CG 3.25Å; L337-L341 WeakPolarHBondContact O-CG 3.21Å; L337-L341 PolarHBondContact O-N 2.99Å
338	L	92.5	Very high	91	Very high	74 Å²	74	25.7 Å²	25.7	39%	0.387	14%	0.138	S	C	.	.	H	α-helix	trans	-64.7	-45	176	-178.3	58.2	0	0	0	112.3	F198 L334 A335 I336 V340 L341 L342	F198-L338 HydrophobicContact CE2-CB 4.13Å; F198-L338 HydrophobicContact CE2-CD2 3.6Å; F198-L338 HydrophobicContact CE2-CG 3.81Å; F198-L338 HydrophobicContact CZ-CD2 3.63Å; F198-L338 HydrophobicContact CZ-CG 4.35Å; L334-L338 WeakPolarHBondContact O-CB 3.43Å; L334-L338 PolarHBondContact O-N 3.45Å; A335-L338 PolarHBondContact O-N 3.46Å; I336-L338 VanDerWaalsContact C-N 3.28Å; I336-L338 PolarHBondContact O-N 3.15Å; L338-V340 VanDerWaalsContact C-N 3.3Å; L338-V340 PolarHBondContact O-N 3.15Å; L338-L341 PolarHBondContact O-N 3Å; L338-L342 HydrophobicContact CD1-CD1 4.35Å; L338-L342 HydrophobicContact CD1-CG 4.36Å; L338-L342 HydrophobicContact CG-CD1 4.3Å; L338-L342 WeakPolarHBondContact O-CG 3.27Å; L338-L342 PolarHBondContact O-N 3.27Å
339	S	91.6	Very high	90.8	Very high	6 Å²	6	25 Å²	25	4%	0.042	13%	0.133	C	C	.	.	H	α-helix	trans	-55.8	-45.8	175.7	-170.7	0	0	0	0	111.8	A335 I336 L342 T343	A335-S339 WeakPolarHBondContact O-CB 3.45Å; A335-S339 PolarHBondContact O-N 2.66Å; I336-S339 WeakPolarHBondContact O-CB 3.42Å; I336-S339 PolarHBondContact O-N 3.06Å; S339-L342 PolarHBondContact O-N 3.19Å; S339-T343 WeakPolarHBondContact O-CB 3.25Å; S339-T343 PolarHBondContact O-N 3.09Å; S339-T343 PolarHBondContact O-OG1 2.99Å
340	V	91.9	Very high	90.5	Very high	6 Å²	6	26.4 Å²	26.4	4%	0.036	14%	0.142	C	C	.	.	H	α-helix	trans	-65.2	-44.6	179.7	169.6	0	0	0	0	111.4	Y135 I138 L139 I336 L337 L338 L342 T343 V344	Y135-V340 VanDerWaalsContact CB-CG1 3.4Å; Y135-V340 HydrophobicContact CD1-CB 4.15Å; Y135-V340 HydrophobicContact CD1-CG1 3.64Å; Y135-V340 HydrophobicContact CD1-CG2 3.62Å; Y135-V340 HydrophobicContact CE1-CG2 4.08Å; Y135-V340 HydrophobicContact CG-CG1 3.69Å; Y135-V340 HydrophobicContact CG-CG2 4.5Å; I138-V340 HydrophobicContact CD1-CG2 4.41Å; L139-V340 HydrophobicContact CD1-CG1 4.47Å; L139-V340 HydrophobicContact CD2-CG1 4.38Å; L139-V340 HydrophobicContact CG-CG1 4.14Å; I336-V340 HydrophobicContact CG2-CG2 4.16Å; I336-V340 WeakPolarHBondContact O-CB 3.34Å; I336-V340 VanDerWaalsContact O-CG2 3.25Å; I336-V340 WeakPolarHBondContact O-CG2 2.77Å; I336-V340 PolarHBondContact O-N 2.79Å; L337-V340 PolarHBondContact O-N 2.94Å; L338-V340 VanDerWaalsContact C-N 3.3Å; L338-V340 PolarHBondContact O-N 3.15Å; V340-L342 VanDerWaalsContact C-N 3.26Å; V340-L342 PolarHBondContact O-N 3.11Å; V340-T343 PolarHBondContact O-N 2.68Å; V340-V344 HydrophobicContact CG1-CG2 4.33Å; V340-V344 WeakPolarHBondContact O-CG2 3.37Å; V340-V344 PolarHBondContact O-N 3.16Å
341	L	90.9	Very high	90.4	Very high	34 Å²	34	25.3 Å²	25.3	18%	0.178	14%	0.137	C	C	.	.	H	α-helix	trans	-58.7	-38.5	176.2	-73.3	170.4	0	0	0	112.5	L139 V171 I176 L337 L338 T343 P345	L139-L341 HydrophobicContact CD1-CD2 3.75Å; L139-L341 HydrophobicContact CD2-CD2 4.09Å; L139-L341 HydrophobicContact CD2-CG 4.07Å; V171-L341 HydrophobicContact CG1-CD2 3.53Å; I176-L341 HydrophobicContact CD1-CD2 4.19Å; I176-L341 HydrophobicContact CG1-CD2 4.05Å; L337-L341 VanDerWaalsContact O-CG 3.25Å; L337-L341 WeakPolarHBondContact O-CG 3.21Å; L337-L341 PolarHBondContact O-N 2.99Å; L338-L341 PolarHBondContact O-N 3Å; L341-T343 VanDerWaalsContact C-N 3.35Å; L341-P345 WeakPolarHBondContact O-CD 3.16Å
342	L	87.6	Confident	90.2	Very high	39 Å²	39	22.7 Å²	22.7	20%	0.204	12%	0.12	C	C	.	.	H	α-helix	trans	-73.9	-26.9	176.9	-65.7	174.7	0	0	0	112.6	T191 L194 L338 S339 V340 L346	T191-L342 HydrophobicContact CG2-CD2 4.28Å; L194-L342 HydrophobicContact CD2-CD1 4.02Å; L338-L342 HydrophobicContact CD1-CD1 4.35Å; L338-L342 HydrophobicContact CD1-CG 4.36Å; L338-L342 HydrophobicContact CG-CD1 4.3Å; L338-L342 WeakPolarHBondContact O-CG 3.27Å; L338-L342 PolarHBondContact O-N 3.27Å; S339-L342 PolarHBondContact O-N 3.19Å; V340-L342 VanDerWaalsContact C-N 3.26Å; V340-L342 PolarHBondContact O-N 3.11Å; L342-L346 VanDerWaalsContact O-CG 3.27Å; L342-L346 WeakPolarHBondContact O-CG 3.43Å
343	T	89.4	Confident	89.7	Confident	4 Å²	4	28.6 Å²	28.6	3%	0.025	15%	0.145	C	C	.	.	H	α-helix	trans	-87.8	-32.8	-174.1	-55.4	0	0	0	0	113.1	N52 Y135 S339 V340 L341 L346 I347	N52-T343 PolarHBondContact OD1-OG1 3.14Å; Y135-T343 HydrophobicContact CE2-CG2 3.65Å; Y135-T343 WeakPolarHBondContact OH-CG2 3.35Å; S339-T343 WeakPolarHBondContact O-CB 3.25Å; S339-T343 PolarHBondContact O-N 3.09Å; S339-T343 PolarHBondContact O-OG1 2.99Å; V340-T343 PolarHBondContact O-N 2.68Å; L341-T343 VanDerWaalsContact C-N 3.35Å; T343-L346 VanDerWaalsContact O-CB 3.28Å; T343-L346 WeakPolarHBondContact O-CB 3.33Å; T343-L346 PolarHBondContact O-N 3.21Å; T343-I347 HydrophobicContact CG2-CD1 4.4Å; T343-I347 HydrophobicContact CG2-CG1 4.34Å; T343-I347 PolarHBondContact O-N 3.09Å
344	V	91.8	Very high	89.4	Confident	0 Å²	0	28 Å²	28	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-55.3	-48.3	179.9	169.3	0	0	0	0	113	M132 Y135 L136 I176 V340 L346 I347 H348	M132-V344 HydrophobicContact CG-CG1 4.27Å; M132-V344 HydrophobicContact SD-CG1 4.33Å; Y135-V344 HydrophobicContact CD2-CG2 3.73Å; Y135-V344 HydrophobicContact CG-CG2 3.98Å; L136-V344 HydrophobicContact CD2-CG2 4.38Å; I176-V344 HydrophobicContact CG2-CB 4.46Å; I176-V344 HydrophobicContact CG2-CG1 3.6Å; V340-V344 HydrophobicContact CG1-CG2 4.33Å; V340-V344 WeakPolarHBondContact O-CG2 3.37Å; V340-V344 PolarHBondContact O-N 3.16Å; V344-L346 PolarHBondContact O-N 3.42Å; V344-I347 PolarHBondContact O-N 2.85Å; V344-H348 WeakPolarHBondContact O-CB 3.36Å; V344-H348 PolarHBondContact O-N 3.31Å
345	P	88.1	Confident	89.2	Confident	17 Å²	17	25.4 Å²	25.4	11%	0.11	13%	0.13	C	C	.	.	H	α-helix	trans	-59.2	-29.3	176.3	-24.8	35.1	0	0	0	113.5	L179 L341 H348 F349	L179-P345 HydrophobicContact CB-CB 4.34Å; L179-P345 HydrophobicContact CB-CG 3.72Å; L179-P345 HydrophobicContact CD2-CG 4.2Å; L341-P345 WeakPolarHBondContact O-CD 3.16Å; P345-H348 PolarHBondContact O-N 2.93Å; P345-F349 PolarHBondContact O-N 3.45Å; P345-F349 VanDerWaalsContact O-N 3.16Å
346	L	84.8	Confident	88.9	Confident	35 Å²	35	27 Å²	27	18%	0.183	14%	0.137	C	C	.	.	H	α-helix	trans	-72.9	-40.7	-177.3	-46.1	-169	0	0	0	111.5	N52 L188 L342 T343 V344 P350	N52-L346 WeakPolarHBondContact ND2-CD1 3.47Å; L188-L346 HydrophobicContact CD1-CD1 4.1Å; L188-L346 HydrophobicContact CD1-CD2 3.08Å; L188-L346 HydrophobicContact CD1-CG 4.18Å; L188-L346 HydrophobicContact CD2-CD2 4.38Å; L188-L346 HydrophobicContact CG-CD1 4.27Å; L188-L346 HydrophobicContact CG-CD2 4.03Å; L342-L346 VanDerWaalsContact O-CG 3.27Å; L342-L346 WeakPolarHBondContact O-CG 3.43Å; T343-L346 VanDerWaalsContact O-CB 3.28Å; T343-L346 WeakPolarHBondContact O-CB 3.33Å; T343-L346 PolarHBondContact O-N 3.21Å; V344-L346 PolarHBondContact O-N 3.42Å; L346-P350 WeakPolarHBondContact O-CD 3.43Å
347	I	89.1	Confident	88.4	Confident	24 Å²	24	29.2 Å²	29.2	12%	0.123	15%	0.149	C	C	.	.	H	α-helix	trans	-75.3	-31.7	175.2	-59.8	-161.1	0	0	0	110.7	N128 A131 M132 Y135 T343 V344 F349 P350 A351	N128-I347 HydrophobicContact CB-CG2 3.64Å; A131-I347 HydrophobicContact CB-CD1 3.84Å; A131-I347 HydrophobicContact CB-CG2 4.28Å; M132-I347 HydrophobicContact CG-CB 3.96Å; M132-I347 HydrophobicContact CG-CG2 3.73Å; M132-I347 HydrophobicContact SD-CG2 4.38Å; Y135-I347 HydrophobicContact CD2-CD1 4.41Å; Y135-I347 HydrophobicContact CE2-CD1 3.52Å; Y135-I347 HydrophobicContact CE2-CG1 4.39Å; T343-I347 HydrophobicContact CG2-CD1 4.4Å; T343-I347 HydrophobicContact CG2-CG1 4.34Å; T343-I347 PolarHBondContact O-N 3.09Å; V344-I347 PolarHBondContact O-N 2.85Å; I347-F349 VanDerWaalsContact C-N 3.32Å; I347-F349 PolarHBondContact O-N 2.93Å; I347-P350 VanDerWaalsContact O-CD 3.25Å; I347-P350 WeakPolarHBondContact O-CD 3.01Å; I347-P350 VanDerWaalsContact O-CG 3.32Å; I347-P350 WeakPolarHBondContact O-CG 3.28Å; I347-A351 PolarHBondContact O-N 2.9Å
348	H	90.1	Very high	88	Confident	1 Å²	1	32.4 Å²	32.4	1%	0.005	16%	0.164	C	C	.	.	H	α-helix	trans	-62.1	-39.4	176.4	-179	-90.4	0	0	0	112.3	M132 V344 P345 A351 R352 T374	M132-H348 VanDerWaalsContact SD-CA 3.52Å; M132-H348 HydrophobicContact SD-CB 3.61Å; V344-H348 WeakPolarHBondContact O-CB 3.36Å; V344-H348 PolarHBondContact O-N 3.31Å; P345-H348 PolarHBondContact O-N 2.93Å; H348-A351 WeakPolarHBondContact O-CB 3.39Å; H348-A351 PolarHBondContact O-N 3.44Å; H348-R352 WeakPolarHBondContact O-CB 3.43Å; H348-R352 PolarHBondContact O-N 2.99Å; H348-T374 VanDerWaalsContact CE1-CG2 3.48Å; H348-T374 WeakPolarHBondContact CE1-CG2 3.47Å; H348-T374 PolarHBondContact CE1-OG1 2.92Å
349	F	84.6	Confident	87.6	Confident	74 Å²	74	34.7 Å²	34.7	33%	0.325	18%	0.177	S	C	.	.	H	α-helix	trans	-57.1	-55	-177.8	-174.4	-90	0	0	0	114.7	I185 P345 I347 A351 R352 K353	I185-F349 HydrophobicContact CD1-CB 3.98Å; I185-F349 HydrophobicContact CD1-CD1 3.78Å; I185-F349 HydrophobicContact CD1-CD2 3.57Å; I185-F349 HydrophobicContact CD1-CE1 4.11Å; I185-F349 HydrophobicContact CD1-CE2 3.92Å; I185-F349 HydrophobicContact CD1-CG 3.5Å; I185-F349 HydrophobicContact CD1-CZ 4.18Å; I185-F349 HydrophobicContact CG1-CD2 4.27Å; I185-F349 HydrophobicContact CG1-CE2 4.48Å; P345-F349 PolarHBondContact O-N 3.45Å; P345-F349 VanDerWaalsContact O-N 3.16Å; I347-F349 VanDerWaalsContact C-N 3.32Å; I347-F349 PolarHBondContact O-N 2.93Å; F349-A351 VanDerWaalsContact C-N 3.3Å; F349-A351 PolarHBondContact O-N 3.37Å; F349-R352 VanDerWaalsContact CD2-NH2 3.28Å; F349-R352 PolarHBondContact O-N 2.85Å; F349-K353 PolarHBondContact O-N 3.47Å
350	P	82.8	Confident	87.2	Confident	35 Å²	35	38.9 Å²	38.9	23%	0.227	19%	0.194	C	C	.	.	H	α-helix	trans	-64.7	-33.6	176.1	25.5	-33.3	0	0	0	112	L346 I347 K353 A354	L346-P350 WeakPolarHBondContact O-CD 3.43Å; I347-P350 VanDerWaalsContact O-CD 3.25Å; I347-P350 WeakPolarHBondContact O-CD 3.01Å; I347-P350 VanDerWaalsContact O-CG 3.32Å; I347-P350 WeakPolarHBondContact O-CG 3.28Å; P350-K353 PolarHBondContact O-N 3.43Å; P350-A354 WeakPolarHBondContact O-CB 3.46Å; P350-A354 PolarHBondContact O-N 2.97Å
351	A	89	Confident	86.5	Confident	0 Å²	0	40.1 Å²	40.1	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-60.1	-48.7	174.3	0	0	0	0	0	111.7	N128 M132 I347 H348 F349 A354 V355	N128-A351 HydrophobicContact CB-CB 3.7Å; N128-A351 PolarHBondContact ND2-N 3.33Å; M132-A351 HydrophobicContact CE-CB 4.09Å; I347-A351 PolarHBondContact O-N 2.9Å; H348-A351 WeakPolarHBondContact O-CB 3.39Å; H348-A351 PolarHBondContact O-N 3.44Å; F349-A351 VanDerWaalsContact C-N 3.3Å; F349-A351 PolarHBondContact O-N 3.37Å; A351-A354 PolarHBondContact O-N 2.92Å; A351-V355 WeakPolarHBondContact O-CG2 3.34Å; A351-V355 PolarHBondContact O-N 3.02Å
352	R	89.4	Confident	85.6	Confident	7 Å²	7	42.6 Å²	42.6	3%	0.026	24%	0.242	C	C	.	.	H	α-helix	trans	-61.6	-44.7	175.8	177.4	177.3	63.7	-151.1	1.2	111.7	A180 H348 F349 A354 V355 I356 H370 T374 I377	A180-R352 PolarHBondContact O-NH1 2.9Å; H348-R352 WeakPolarHBondContact O-CB 3.43Å; H348-R352 PolarHBondContact O-N 2.99Å; F349-R352 VanDerWaalsContact CD2-NH2 3.28Å; F349-R352 PolarHBondContact O-N 2.85Å; R352-A354 VanDerWaalsContact C-N 3.32Å; R352-A354 PolarHBondContact O-N 3.16Å; R352-V355 PolarHBondContact O-N 3.46Å; R352-I356 HydrophobicContact CG-CD1 3.67Å; R352-I356 HydrophobicContact CG-CG1 4.27Å; R352-I356 VanDerWaalsContact O-CG1 3.32Å; R352-I356 WeakPolarHBondContact O-CG1 3.45Å; R352-I356 PolarHBondContact O-N 3.14Å; R352-H370 PolarHBondContact NE-CE1 2.96Å; R352-H370 VanDerWaalsContact NE-CE1 3.27Å; R352-H370 PolarHBondContact NH1-CE1 3.39Å; R352-H370 PolarHBondContact NH1-NE2 3.03Å; R352-H370 PolarHBondContact NH2-CE1 3.29Å; R352-H370 PolarHBondContact NH2-NE2 3.49Å; R352-T374 WeakPolarHBondContact CD-OG1 3.28Å; R352-T374 PolarHBondContact NH1-OG1 3.44Å; R352-T374 VanDerWaalsContact NH1-OG1 3.08Å; R352-I377 HydrophobicContact CB-CD1 4.06Å
353	K	83.8	Confident	85	Confident	128 Å²	128	49.7 Å²	49.7	56%	0.557	27%	0.266	S	S	*	.	H	α-helix	trans	-57.6	-46.3	177.6	-174.3	-177.7	176.2	-173.5	0	110.9	F349 P350 I356 L357	F349-K353 PolarHBondContact O-N 3.47Å; P350-K353 PolarHBondContact O-N 3.43Å; K353-I356 PolarHBondContact O-N 3.35Å; K353-L357 VanDerWaalsContact O-CB 3.27Å; K353-L357 WeakPolarHBondContact O-CB 3.46Å; K353-L357 PolarHBondContact O-N 3.42Å
354	A	85.9	Confident	84.3	Confident	1 Å²	1	55.2 Å²	55.2	1%	0.008	30%	0.302	C	S	.	.	H	α-helix	trans	-62.4	-45.6	177.3	0	0	0	0	0	112	I124 V125 P350 A351 R352 I356 L357 M358	I124-A354 HydrophobicContact CG2-CB 4.37Å; V125-A354 HydrophobicContact CG2-CB 3.64Å; P350-A354 WeakPolarHBondContact O-CB 3.46Å; P350-A354 PolarHBondContact O-N 2.97Å; A351-A354 PolarHBondContact O-N 2.92Å; R352-A354 VanDerWaalsContact C-N 3.32Å; R352-A354 PolarHBondContact O-N 3.16Å; A354-I356 PolarHBondContact O-N 2.9Å; A354-L357 PolarHBondContact O-N 3.06Å; A354-M358 WeakPolarHBondContact O-CB 3.45Å; A354-M358 VanDerWaalsContact O-CG 3.22Å; A354-M358 WeakPolarHBondContact O-CG 3.39Å; A354-M358 PolarHBondContact O-N 2.7Å
355	V	89.4	Confident	83.7	Confident	25 Å²	25	61.1 Å²	61.1	15%	0.152	33%	0.328	C	S	.	.	H	α-helix	trans	-60.3	-47.6	177.2	170	0	0	0	0	112	V125 A351 R352 L357 M358 L359 I377	V125-V355 HydrophobicContact CB-CG2 4.48Å; V125-V355 HydrophobicContact CG1-CG2 3.9Å; V125-V355 HydrophobicContact CG2-CG2 3.66Å; A351-V355 WeakPolarHBondContact O-CG2 3.34Å; A351-V355 PolarHBondContact O-N 3.02Å; R352-V355 PolarHBondContact O-N 3.46Å; V355-L357 PolarHBondContact O-N 3.06Å; V355-M358 PolarHBondContact O-N 2.93Å; V355-L359 HydrophobicContact CG1-CD1 3.68Å; V355-L359 HydrophobicContact CG1-CG 4.38Å; V355-L359 WeakPolarHBondContact O-CB 3.39Å; V355-L359 WeakPolarHBondContact O-CG 3.45Å; V355-L359 PolarHBondContact O-N 3.23Å; V355-I377 HydrophobicContact CB-CD1 4.31Å; V355-I377 HydrophobicContact CG2-CD1 3.93Å; V355-I377 HydrophobicContact CG2-CG1 4.38Å
356	I	87.2	Confident	83.6	Confident	42 Å²	42	62.5 Å²	62.5	22%	0.215	34%	0.338	C	S	.	.	H	α-helix	trans	-64.1	-44.1	-179.6	-66.7	174.5	0	0	0	110.4	R352 K353 A354 M358 L359 F360 G361 T369	R352-I356 HydrophobicContact CG-CD1 3.67Å; R352-I356 HydrophobicContact CG-CG1 4.27Å; R352-I356 VanDerWaalsContact O-CG1 3.32Å; R352-I356 WeakPolarHBondContact O-CG1 3.45Å; R352-I356 PolarHBondContact O-N 3.14Å; K353-I356 PolarHBondContact O-N 3.35Å; A354-I356 PolarHBondContact O-N 2.9Å; I356-M358 VanDerWaalsContact C-N 3.29Å; I356-M358 PolarHBondContact O-N 3.28Å; I356-L359 PolarHBondContact O-N 2.99Å; I356-F360 PolarHBondContact O-N 3.35Å; I356-G361 PolarHBondContact O-N 3.45Å; I356-T369 HydrophobicContact CD1-CG2 4.28Å; I356-T369 HydrophobicContact CG1-CG2 4.05Å; I356-T369 HydrophobicContact CG2-CG2 4.46Å
357	L	83.1	Confident	83.7	Confident	54 Å²	54	67.5 Å²	67.5	28%	0.283	36%	0.355	S	S	.	.	H	α-helix	trans	-61.5	-38	178.3	-175.4	65.7	0	0	0	112	K353 A354 V355 G361	K353-L357 VanDerWaalsContact O-CB 3.27Å; K353-L357 WeakPolarHBondContact O-CB 3.46Å; K353-L357 PolarHBondContact O-N 3.42Å; A354-L357 PolarHBondContact O-N 3.06Å; V355-L357 PolarHBondContact O-N 3.06Å; L357-G361 WeakPolarHBondContact O-CA 3.45Å; L357-G361 PolarHBondContact O-N 3.47Å
358	M	85.5	Confident	83.7	Confident	74 Å²	74	72.5 Å²	72.5	37%	0.365	38%	0.381	S	S	.	.	H	α-helix	trans	-73.5	-43.4	178.9	-71.6	172.8	72.7	0	0	113.3	I118 L122 A354 V355 I356	I118-M358 HydrophobicContact CG2-CE 4.05Å; L122-M358 HydrophobicContact CB-CE 4.05Å; A354-M358 WeakPolarHBondContact O-CB 3.45Å; A354-M358 VanDerWaalsContact O-CG 3.22Å; A354-M358 WeakPolarHBondContact O-CG 3.39Å; A354-M358 PolarHBondContact O-N 2.7Å; V355-M358 PolarHBondContact O-N 2.93Å; I356-M358 VanDerWaalsContact C-N 3.29Å; I356-M358 PolarHBondContact O-N 3.28Å
359	L	84.6	Confident	83.6	Confident	123 Å²	123	74 Å²	74	64%	0.644	39%	0.39	S	S	*	.	H	α-helix	trans	-84.3	-41.6	-173.9	-68.1	176.8	0	0	0	113.3	V355 I356	V355-L359 HydrophobicContact CG1-CD1 3.68Å; V355-L359 HydrophobicContact CG1-CG 4.38Å; V355-L359 WeakPolarHBondContact O-CB 3.39Å; V355-L359 WeakPolarHBondContact O-CG 3.45Å; V355-L359 PolarHBondContact O-N 3.23Å; I356-L359 PolarHBondContact O-N 2.99Å
360	F	82.8	Confident	83.8	Confident	94 Å²	94	71 Å²	71	41%	0.412	38%	0.377	S	S	.	.	H	α-helix	trans	-114.3	-9	-169.8	-61.2	-75	0	0	0	113.2	I356 R363 T369	I356-F360 PolarHBondContact O-N 3.35Å; F360-R363 WeakPolarHBondContact O-CD 3.26Å; F360-R363 VanDerWaalsContact O-CG 3.23Å; F360-R363 WeakPolarHBondContact O-CG 3.37Å; F360-R363 PolarHBondContact O-NE 3.4Å; F360-T369 HydrophobicContact CD2-CG2 3.6Å; F360-T369 HydrophobicContact CE2-CG2 3.58Å; F360-T369 HydrophobicContact CG-CG2 4.36Å; F360-T369 HydrophobicContact CZ-CG2 4.33Å
361	G	77.1	Confident	84.2	Confident	32 Å²	32	71.9 Å²	71.9	33%	0.33	38%	0.379	S	S	.	.			trans	69.7	-159.3	-175.3	0	0	0	0	0	112.5	I356 L357 R363	I356-G361 PolarHBondContact O-N 3.45Å; L357-G361 WeakPolarHBondContact O-CA 3.45Å; L357-G361 PolarHBondContact O-N 3.47Å; G361-R363 PolarHBondContact O-N 2.86Å
362	G	70.8	Confident	84.3	Confident	86 Å²	86	75 Å²	75	89%	0.887	40%	0.398	S	S	*	.	S	Bend	trans	-76.2	34.2	178.2	0	0	0	0	0	114.7
363	R	75.2	Confident	84.5	Confident	187 Å²	187	75.1 Å²	75.1	71%	0.706	40%	0.4	S	S	*	.	P	Polyproline II helix	trans	-64.7	152.6	178.6	-78.6	-178.6	-164	-128.4	3.9	111.2	F360 G361	F360-R363 WeakPolarHBondContact O-CD 3.26Å; F360-R363 VanDerWaalsContact O-CG 3.23Å; F360-R363 WeakPolarHBondContact O-CG 3.37Å; F360-R363 PolarHBondContact O-NE 3.4Å; G361-R363 PolarHBondContact O-N 2.86Å
364	P	75.3	Confident	84.9	Confident	120 Å²	120	69 Å²	69	78%	0.779	37%	0.374	S	S	*	.	P	Polyproline II helix	trans	-60.3	152.9	177.9	26.5	-35.2	0	0	0	111.1	S366	P364-S366 PolarHBondContact O-N 3.35Å
365	F	79.6	Confident	85.3	Confident	124 Å²	124	73.2 Å²	73.2	54%	0.544	40%	0.395	S	S	.	.	P	Polyproline II helix	trans	-54.7	129.4	-179.8	176	-92.7	0	0	0	111.5	W367 H370	F365-W367 AromaticContact CE1-CD1 3.81Å; F365-W367 HydrophobicContact CE1-CD2 4.15Å; F365-W367 HydrophobicContact CE1-CG 4.04Å; F365-W367 AromaticContact CE1-NE1 3.78Å; F365-W367 HydrophobicContact CZ-CD2 4.21Å; F365-W367 HydrophobicContact CZ-CG 4.47Å; F365-H370 HydrophobicContact CE2-CB 4.18Å; F365-H370 AromaticContact CE2-CE1 3.94Å; F365-H370 AromaticContact CE2-CG 3.93Å; F365-H370 AromaticContact CE2-ND1 3.48Å; F365-H370 WeakPolarHBondContact CE2-ND1 3.21Å; F365-H370 HydrophobicContact CZ-CB 4.31Å
366	S	86.1	Confident	85.6	Confident	47 Å²	47	77 Å²	77	33%	0.329	41%	0.414	S	S	.	.			trans	-127.5	134.7	171.8	91.4	0	0	0	0	110.1	P364 L368 T369 H370	P364-S366 PolarHBondContact O-N 3.35Å; S366-L368 VanDerWaalsContact C-N 3.31Å; S366-L368 PolarHBondContact O-N 2.96Å; S366-T369 WeakPolarHBondContact OG-CB 3.42Å; S366-T369 PolarHBondContact OG-N 3.18Å; S366-T369 VanDerWaalsContact OG-N 3.12Å; S366-T369 PolarHBondContact OG-OG1 3.32Å; S366-H370 WeakPolarHBondContact O-CB 3.45Å; S366-H370 PolarHBondContact O-N 2.7Å
367	W	86.3	Confident	86	Confident	140 Å²	140	75.4 Å²	75.4	53%	0.53	41%	0.406	S	S	.	.	H	α-helix	trans	-63.4	-37.4	178.6	-89.9	106	0	0	0	112.3	P183 F365 H370 I371	P183-W367 HydrophobicContact CG-CH2 4.23Å; F365-W367 AromaticContact CE1-CD1 3.81Å; F365-W367 HydrophobicContact CE1-CD2 4.15Å; F365-W367 HydrophobicContact CE1-CG 4.04Å; F365-W367 AromaticContact CE1-NE1 3.78Å; F365-W367 HydrophobicContact CZ-CD2 4.21Å; F365-W367 HydrophobicContact CZ-CG 4.47Å; W367-H370 WeakPolarHBondContact O-CB 3.13Å; W367-H370 PolarHBondContact O-N 3.27Å; W367-I371 HydrophobicContact CE3-CD1 4.22Å; W367-I371 HydrophobicContact CE3-CG1 4.34Å; W367-I371 WeakPolarHBondContact O-CB 3.1Å; W367-I371 VanDerWaalsContact O-CG1 3.25Å; W367-I371 WeakPolarHBondContact O-CG1 3.4Å; W367-I371 PolarHBondContact O-N 3.28Å
368	L	88.8	Confident	86.6	Confident	129 Å²	129	73 Å²	73	68%	0.675	39%	0.393	S	S	*	.	H	α-helix	trans	-64.4	-49.6	179.2	-176.8	64.4	0	0	0	111.5	S366 H370 I371 V372	S366-L368 VanDerWaalsContact C-N 3.31Å; S366-L368 PolarHBondContact O-N 2.96Å; L368-H370 PolarHBondContact O-N 2.83Å; L368-I371 PolarHBondContact O-N 3.32Å; L368-V372 HydrophobicContact CD1-CG2 3.93Å; L368-V372 HydrophobicContact CG-CG2 4.31Å; L368-V372 WeakPolarHBondContact O-CB 3.36Å; L368-V372 VanDerWaalsContact O-CG2 3.26Å; L368-V372 WeakPolarHBondContact O-CG2 3.48Å; L368-V372 PolarHBondContact O-N 2.81Å
369	T	88.4	Confident	87.1	Confident	32 Å²	32	71 Å²	71	20%	0.196	39%	0.392	C	S	.	.	H	α-helix	trans	-61.4	-37.7	177	-58.5	0	0	0	0	110.9	I356 F360 S366 S373	I356-T369 HydrophobicContact CD1-CG2 4.28Å; I356-T369 HydrophobicContact CG1-CG2 4.05Å; I356-T369 HydrophobicContact CG2-CG2 4.46Å; F360-T369 HydrophobicContact CD2-CG2 3.6Å; F360-T369 HydrophobicContact CE2-CG2 3.58Å; F360-T369 HydrophobicContact CG-CG2 4.36Å; F360-T369 HydrophobicContact CZ-CG2 4.33Å; S366-T369 WeakPolarHBondContact OG-CB 3.42Å; S366-T369 PolarHBondContact OG-N 3.18Å; S366-T369 VanDerWaalsContact OG-N 3.12Å; S366-T369 PolarHBondContact OG-OG1 3.32Å; T369-S373 WeakPolarHBondContact O-CB 3.38Å; T369-S373 PolarHBondContact O-N 2.63Å
370	H	88.4	Confident	87.7	Confident	10 Å²	10	68.3 Å²	68.3	5%	0.046	38%	0.38	C	S	.	.	H	α-helix	trans	-63.7	-48.2	177.7	-164.7	89.7	0	0	0	112.8	R352 F365 S366 W367 L368 T374	R352-H370 PolarHBondContact NE-CE1 2.96Å; R352-H370 VanDerWaalsContact NE-CE1 3.27Å; R352-H370 PolarHBondContact NH1-CE1 3.39Å; R352-H370 PolarHBondContact NH1-NE2 3.03Å; R352-H370 PolarHBondContact NH2-CE1 3.29Å; R352-H370 PolarHBondContact NH2-NE2 3.49Å; F365-H370 HydrophobicContact CE2-CB 4.18Å; F365-H370 AromaticContact CE2-CE1 3.94Å; F365-H370 AromaticContact CE2-CG 3.93Å; F365-H370 AromaticContact CE2-ND1 3.48Å; F365-H370 WeakPolarHBondContact CE2-ND1 3.21Å; F365-H370 HydrophobicContact CZ-CB 4.31Å; S366-H370 WeakPolarHBondContact O-CB 3.45Å; S366-H370 PolarHBondContact O-N 2.7Å; W367-H370 WeakPolarHBondContact O-CB 3.13Å; W367-H370 PolarHBondContact O-N 3.27Å; L368-H370 PolarHBondContact O-N 2.83Å; H370-T374 WeakPolarHBondContact O-CB 3.43Å; H370-T374 PolarHBondContact O-N 3.47Å; H370-T374 VanDerWaalsContact O-N 3.09Å; H370-T374 PolarHBondContact O-OG1 3.23Å
371	I	91.3	Very high	88.3	Confident	54 Å²	54	63.9 Å²	63.9	28%	0.277	36%	0.36	S	S	.	.	H	α-helix	trans	-66.5	-51.8	179.6	-68.8	165	0	0	0	110.2	M181 W367 L368 S373 T374 L375	M181-I371 HydrophobicContact CE-CD1 4.24Å; M181-I371 HydrophobicContact CE-CG1 3.75Å; W367-I371 HydrophobicContact CE3-CD1 4.22Å; W367-I371 HydrophobicContact CE3-CG1 4.34Å; W367-I371 WeakPolarHBondContact O-CB 3.1Å; W367-I371 VanDerWaalsContact O-CG1 3.25Å; W367-I371 WeakPolarHBondContact O-CG1 3.4Å; W367-I371 PolarHBondContact O-N 3.28Å; L368-I371 PolarHBondContact O-N 3.32Å; I371-S373 PolarHBondContact O-N 2.85Å; I371-T374 PolarHBondContact O-N 3.44Å; I371-T374 VanDerWaalsContact O-N 3.14Å; I371-L375 HydrophobicContact CG2-CD1 3.83Å; I371-L375 HydrophobicContact CG2-CG 4.31Å; I371-L375 WeakPolarHBondContact O-CG 3.35Å; I371-L375 PolarHBondContact O-N 3.47Å
372	V	92.3	Very high	89.2	Confident	66 Å²	66	63.8 Å²	63.8	40%	0.4	35%	0.352	S	S	.	.	H	α-helix	trans	-60.7	-45.6	-177.8	171.7	0	0	0	0	110.9	L368 T374 L375 I376	L368-V372 HydrophobicContact CD1-CG2 3.93Å; L368-V372 HydrophobicContact CG-CG2 4.31Å; L368-V372 WeakPolarHBondContact O-CB 3.36Å; L368-V372 VanDerWaalsContact O-CG2 3.26Å; L368-V372 WeakPolarHBondContact O-CG2 3.48Å; L368-V372 PolarHBondContact O-N 2.81Å; V372-T374 VanDerWaalsContact C-N 3.32Å; V372-T374 PolarHBondContact O-N 3.33Å; V372-L375 PolarHBondContact O-N 3.25Å; V372-I376 HydrophobicContact CG1-CD1 3.6Å; V372-I376 HydrophobicContact CG1-CG1 4.34Å; V372-I376 WeakPolarHBondContact O-CB 3.23Å; V372-I376 VanDerWaalsContact O-CG1 3.26Å; V372-I376 WeakPolarHBondContact O-CG1 3.42Å; V372-I376 PolarHBondContact O-N 3.14Å
373	S	92.1	Very high	90.4	Very high	10 Å²	10	64.9 Å²	64.9	7%	0.07	34%	0.336	C	S	.	.	H	α-helix	trans	-62.2	-40.3	176.8	178.6	0	0	0	0	112	T369 I371 I377	T369-S373 WeakPolarHBondContact O-CB 3.38Å; T369-S373 PolarHBondContact O-N 2.63Å; I371-S373 PolarHBondContact O-N 2.85Å; S373-I377 WeakPolarHBondContact O-CB 3.17Å; S373-I377 WeakPolarHBondContact O-CD1 3.46Å; S373-I377 WeakPolarHBondContact O-CG1 3.47Å; S373-I377 PolarHBondContact O-N 3.5Å
374	T	92.8	Very high	91.4	Very high	0 Å²	0	59.2 Å²	59.2	0%	0	32%	0.319	C	S	.	.	H	α-helix	trans	-63.9	-47.1	178.1	-58.7	0	0	0	0	111.4	A180 M181 H348 R352 H370 I371 V372 I377 L378	A180-T374 HydrophobicContact CB-CG2 4.04Å; M181-T374 HydrophobicContact CG-CG2 4.07Å; H348-T374 VanDerWaalsContact CE1-CG2 3.48Å; H348-T374 WeakPolarHBondContact CE1-CG2 3.47Å; H348-T374 PolarHBondContact CE1-OG1 2.92Å; R352-T374 WeakPolarHBondContact CD-OG1 3.28Å; R352-T374 PolarHBondContact NH1-OG1 3.44Å; R352-T374 VanDerWaalsContact NH1-OG1 3.08Å; H370-T374 WeakPolarHBondContact O-CB 3.43Å; H370-T374 PolarHBondContact O-N 3.47Å; H370-T374 VanDerWaalsContact O-N 3.09Å; H370-T374 PolarHBondContact O-OG1 3.23Å; I371-T374 PolarHBondContact O-N 3.44Å; I371-T374 VanDerWaalsContact O-N 3.14Å; V372-T374 VanDerWaalsContact C-N 3.32Å; V372-T374 PolarHBondContact O-N 3.33Å; T374-I377 PolarHBondContact O-N 2.98Å; T374-L378 HydrophobicContact CG2-CD1 3.91Å; T374-L378 WeakPolarHBondContact O-CB 3.3Å; T374-L378 WeakPolarHBondContact O-CG 3.13Å; T374-L378 PolarHBondContact O-N 3.15Å
375	L	94.4	Very high	92.3	Very high	89 Å²	89	53.5 Å²	53.5	47%	0.466	28%	0.282	S	S	.	.	H	α-helix	trans	-65.5	-40	179.4	-68.2	176.4	0	0	0	112.4	V177 I371 V372 G379	V177-L375 HydrophobicContact CG1-CD2 4.24Å; I371-L375 HydrophobicContact CG2-CD1 3.83Å; I371-L375 HydrophobicContact CG2-CG 4.31Å; I371-L375 WeakPolarHBondContact O-CG 3.35Å; I371-L375 PolarHBondContact O-N 3.47Å; V372-L375 PolarHBondContact O-N 3.25Å; L375-G379 WeakPolarHBondContact O-CA 3.48Å; L375-G379 PolarHBondContact O-N 3.44Å
376	I	95.3	Very high	93	Very high	105 Å²	105	48.9 Å²	48.9	54%	0.538	26%	0.262	S	S	.	.	H	α-helix	trans	-65.4	-48.8	177.4	-69.8	170.2	0	0	0	110.7	V372 G379 V380	V372-I376 HydrophobicContact CG1-CD1 3.6Å; V372-I376 HydrophobicContact CG1-CG1 4.34Å; V372-I376 WeakPolarHBondContact O-CB 3.23Å; V372-I376 VanDerWaalsContact O-CG1 3.26Å; V372-I376 WeakPolarHBondContact O-CG1 3.42Å; V372-I376 PolarHBondContact O-N 3.14Å; I376-G379 PolarHBondContact O-N 3.47Å; I376-V380 WeakPolarHBondContact O-CG2 3.39Å; I376-V380 PolarHBondContact O-N 3.26Å
377	I	95.4	Very high	93.3	Very high	8 Å²	8	53.8 Å²	53.8	4%	0.041	28%	0.278	C	S	.	.	H	α-helix	trans	-61.9	-51.3	-178.9	-67.5	166.9	0	0	0	109.9	I129 M132 R352 V355 S373 T374 G379 V380 V381	I129-I377 HydrophobicContact CG1-CG2 4.45Å; M132-I377 HydrophobicContact CE-CG2 3.74Å; R352-I377 HydrophobicContact CB-CD1 4.06Å; V355-I377 HydrophobicContact CB-CD1 4.31Å; V355-I377 HydrophobicContact CG2-CD1 3.93Å; V355-I377 HydrophobicContact CG2-CG1 4.38Å; S373-I377 WeakPolarHBondContact O-CB 3.17Å; S373-I377 WeakPolarHBondContact O-CD1 3.46Å; S373-I377 WeakPolarHBondContact O-CG1 3.47Å; S373-I377 PolarHBondContact O-N 3.5Å; T374-I377 PolarHBondContact O-N 2.98Å; I377-G379 VanDerWaalsContact C-N 3.3Å; I377-G379 PolarHBondContact O-N 2.88Å; I377-V380 PolarHBondContact O-N 2.98Å; I377-V381 HydrophobicContact CG2-CG2 4.42Å; I377-V381 VanDerWaalsContact O-CG2 3.22Å; I377-V381 WeakPolarHBondContact O-CG2 3.47Å; I377-V381 PolarHBondContact O-N 2.79Å
378	L	95.8	Very high	93.4	Very high	4 Å²	4	48.6 Å²	48.6	2%	0.021	26%	0.262	C	S	.	.	H	α-helix	trans	-65	-34.1	179.2	-69	177.9	0	0	0	112.4	I176 V177 A180 T374 V381 L382	I176-L378 HydrophobicContact CG2-CD1 4.35Å; I176-L378 HydrophobicContact CG2-CD2 4.1Å; V177-L378 HydrophobicContact CB-CD1 4.46Å; V177-L378 HydrophobicContact CG2-CD1 3.72Å; A180-L378 HydrophobicContact CB-CD1 3.9Å; T374-L378 HydrophobicContact CG2-CD1 3.91Å; T374-L378 WeakPolarHBondContact O-CB 3.3Å; T374-L378 WeakPolarHBondContact O-CG 3.13Å; T374-L378 PolarHBondContact O-N 3.15Å; L378-V381 PolarHBondContact O-N 3.5Å; L378-L382 VanDerWaalsContact O-CB 3.23Å; L378-L382 WeakPolarHBondContact O-CB 3.25Å; L378-L382 PolarHBondContact O-N 2.68Å
379	G	96.3	Very high	93.4	Very high	32 Å²	32	47.5 Å²	47.5	33%	0.33	26%	0.263	S	S	.	.	H	α-helix	trans	-62	-45.6	174.1	0	0	0	0	0	112.4	L375 I376 I377 L382 M383	L375-G379 WeakPolarHBondContact O-CA 3.48Å; L375-G379 PolarHBondContact O-N 3.44Å; I376-G379 PolarHBondContact O-N 3.47Å; I377-G379 VanDerWaalsContact C-N 3.3Å; I377-G379 PolarHBondContact O-N 2.88Å; G379-L382 PolarHBondContact O-N 2.98Å; G379-M383 WeakPolarHBondContact O-CG 3.35Å; G379-M383 PolarHBondContact O-N 3.02Å
380	V	96.7	Very high	93.4	Very high	66 Å²	66	47.2 Å²	47.2	40%	0.4	26%	0.26	S	S	.	.	H	α-helix	trans	-63.6	-44.8	175.1	171.9	0	0	0	0	111.1	I129 I376 I377 L382 M383 L384	I129-V380 HydrophobicContact CD1-CG1 4.45Å; I129-V380 HydrophobicContact CG2-CG1 4.22Å; I376-V380 WeakPolarHBondContact O-CG2 3.39Å; I376-V380 PolarHBondContact O-N 3.26Å; I377-V380 PolarHBondContact O-N 2.98Å; V380-L382 VanDerWaalsContact C-N 3.34Å; V380-L382 PolarHBondContact O-N 2.99Å; V380-M383 PolarHBondContact O-N 3.35Å; V380-L384 HydrophobicContact CG1-CD1 4.21Å; V380-L384 WeakPolarHBondContact O-CG 3.34Å; V380-L384 PolarHBondContact O-N 2.73Å
381	V	96.8	Very high	93.5	Very high	0 Å²	0	46.7 Å²	46.7	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-60.1	-44.9	177.5	173.5	0	0	0	0	111.1	I129 M132 L136 I377 L378 L384 A385	I129-V381 HydrophobicContact CB-CG2 4.32Å; I129-V381 HydrophobicContact CG1-CG2 4.24Å; I129-V381 HydrophobicContact CG2-CG2 4.05Å; M132-V381 HydrophobicContact CB-CB 4.44Å; M132-V381 HydrophobicContact CB-CG1 3.57Å; M132-V381 HydrophobicContact CB-CG2 3.92Å; M132-V381 HydrophobicContact CE-CG2 3.92Å; M132-V381 HydrophobicContact SD-CG2 4.49Å; L136-V381 HydrophobicContact CD1-CG1 3.62Å; L136-V381 HydrophobicContact CG-CG1 3.88Å; I377-V381 HydrophobicContact CG2-CG2 4.42Å; I377-V381 VanDerWaalsContact O-CG2 3.22Å; I377-V381 WeakPolarHBondContact O-CG2 3.47Å; I377-V381 PolarHBondContact O-N 2.79Å; L378-V381 PolarHBondContact O-N 3.5Å; V381-L384 PolarHBondContact O-N 2.98Å; V381-A385 WeakPolarHBondContact O-CB 3.24Å; V381-A385 PolarHBondContact O-N 3.23Å
382	L	96.1	Very high	93.5	Very high	30 Å²	30	47.5 Å²	47.5	16%	0.157	26%	0.257	C	S	.	.	H	α-helix	trans	-63	-44.3	178.4	179.9	61.6	0	0	0	111.5	L136 L168 I169 T172 L378 G379 V380 A385 I386	L136-L382 HydrophobicContact CD1-CB 4.34Å; L136-L382 HydrophobicContact CD1-CD1 4.29Å; L168-L382 HydrophobicContact CD2-CD1 3.62Å; L168-L382 HydrophobicContact CG-CD1 3.67Å; I169-L382 HydrophobicContact CG1-CD2 4.4Å; T172-L382 HydrophobicContact CG2-CD2 4.46Å; L378-L382 VanDerWaalsContact O-CB 3.23Å; L378-L382 WeakPolarHBondContact O-CB 3.25Å; L378-L382 PolarHBondContact O-N 2.68Å; G379-L382 PolarHBondContact O-N 2.98Å; V380-L382 VanDerWaalsContact C-N 3.34Å; V380-L382 PolarHBondContact O-N 2.99Å; L382-A385 PolarHBondContact O-N 3.4Å; L382-I386 HydrophobicContact CD1-CD1 4.01Å; L382-I386 HydrophobicContact CD1-CG1 4.34Å; L382-I386 HydrophobicContact CG-CD1 3.98Å; L382-I386 WeakPolarHBondContact O-CG1 3.35Å; L382-I386 PolarHBondContact O-N 3Å
383	M	95.6	Very high	93.5	Very high	110 Å²	110	46.1 Å²	46.1	54%	0.542	25%	0.247	S	C	.	.	H	α-helix	trans	-60.8	-46.3	176.1	-73.9	-63.3	178.2	0	0	111.7	G379 V380 A385 I386 F387	G379-M383 WeakPolarHBondContact O-CG 3.35Å; G379-M383 PolarHBondContact O-N 3.02Å; V380-M383 PolarHBondContact O-N 3.35Å; M383-A385 VanDerWaalsContact C-N 3.34Å; M383-A385 PolarHBondContact O-N 3.03Å; M383-I386 PolarHBondContact O-N 3.14Å; M383-F387 HydrophobicContact CB-CD2 4.43Å; M383-F387 WeakPolarHBondContact O-CD2 3.41Å; M383-F387 PolarHBondContact O-N 2.83Å; M383-F387 HydrophobicContact SD-CD2 4.3Å; M383-F387 HydrophobicContact SD-CE2 3.63Å
384	L	94.9	Very high	93.6	Very high	67 Å²	67	46.3 Å²	46.3	35%	0.351	25%	0.248	S	C	.	.	H	α-helix	trans	-59.2	-45.3	175.4	-72.7	172.9	0	0	0	111.5	I129 V380 V381 I386 F387 V388	I129-L384 HydrophobicContact CG2-CD1 3.49Å; I129-L384 VanDerWaalsContact CG2-CD1 3.49Å; V380-L384 HydrophobicContact CG1-CD1 4.21Å; V380-L384 WeakPolarHBondContact O-CG 3.34Å; V380-L384 PolarHBondContact O-N 2.73Å; V381-L384 PolarHBondContact O-N 2.98Å; L384-I386 VanDerWaalsContact C-N 3.31Å; L384-I386 PolarHBondContact O-N 3.47Å; L384-F387 PolarHBondContact O-N 2.95Å; L384-V388 WeakPolarHBondContact O-CB 3.44Å; L384-V388 WeakPolarHBondContact O-CG2 3.47Å; L384-V388 PolarHBondContact O-N 2.97Å
385	A	94.7	Very high	93.6	Very high	1 Å²	1	46.3 Å²	46.3	1%	0.008	25%	0.248	C	C	.	.	H	α-helix	trans	-64.4	-32.8	179.4	0	0	0	0	0	113.2	L136 K140 L168 V381 L382 M383	L136-A385 HydrophobicContact CB-CB 3.43Å; L136-A385 VanDerWaalsContact CB-CB 3.43Å; L136-A385 HydrophobicContact CD1-CB 4.38Å; K140-A385 WeakPolarHBondContact CD-O 3.39Å; K140-A385 WeakPolarHBondContact CE-O 3.11Å; K140-A385 PolarHBondContact NZ-O 2.65Å; L168-A385 HydrophobicContact CD2-CB 3.99Å; V381-A385 WeakPolarHBondContact O-CB 3.24Å; V381-A385 PolarHBondContact O-N 3.23Å; L382-A385 PolarHBondContact O-N 3.4Å; M383-A385 VanDerWaalsContact C-N 3.34Å; M383-A385 PolarHBondContact O-N 3.03Å
386	I	93.8	Very high	93.5	Very high	26 Å²	26	42.1 Å²	42.1	13%	0.133	23%	0.226	C	C	.	.	H	α-helix	trans	-73.5	-49.1	177.2	-70	169.5	0	0	0	111.1	L168 I169 L382 M383 L384	L168-I386 HydrophobicContact CD2-CG1 4.11Å; I169-I386 HydrophobicContact CD1-CD1 4.37Å; I169-I386 HydrophobicContact CG1-CD1 4.28Å; L382-I386 HydrophobicContact CD1-CD1 4.01Å; L382-I386 HydrophobicContact CD1-CG1 4.34Å; L382-I386 HydrophobicContact CG-CD1 3.98Å; L382-I386 WeakPolarHBondContact O-CG1 3.35Å; L382-I386 PolarHBondContact O-N 3Å; M383-I386 PolarHBondContact O-N 3.14Å; L384-I386 VanDerWaalsContact C-N 3.31Å; L384-I386 PolarHBondContact O-N 3.47Å
387	F	92.4	Very high	93.5	Very high	150 Å²	150	39.3 Å²	39.3	66%	0.658	21%	0.214	S	C	*	.	H	α-helix	trans	-84.2	-27	-171.3	-71	-65.1	0	0	0	114.3	M383 L384 P389	M383-F387 HydrophobicContact CB-CD2 4.43Å; M383-F387 WeakPolarHBondContact O-CD2 3.41Å; M383-F387 PolarHBondContact O-N 2.83Å; M383-F387 HydrophobicContact SD-CD2 4.3Å; M383-F387 HydrophobicContact SD-CE2 3.63Å; L384-F387 PolarHBondContact O-N 2.95Å; F387-P389 WeakPolarHBondContact O-CD 3.37Å
388	V	90.1	Very high	93.5	Very high	31 Å²	31	39.6 Å²	39.6	19%	0.188	22%	0.216	C	C	.	.			trans	-74.7	120.9	177.3	178	0	0	0	0	109.3	F137 K140 L384 D390 N393 V394	F137-V388 WeakPolarHBondContact CE2-O 3.23Å; K140-V388 PolarHBondContact NZ-O 3.36Å; K140-V388 VanDerWaalsContact NZ-O 3.16Å; L384-V388 WeakPolarHBondContact O-CB 3.44Å; L384-V388 WeakPolarHBondContact O-CG2 3.47Å; L384-V388 PolarHBondContact O-N 2.97Å; V388-D390 WeakPolarHBondContact CG1-O 3.15Å; V388-N393 HydrophobicContact CG1-CB 4.43Å; V388-V394 HydrophobicContact CB-CG2 4.49Å; V388-V394 HydrophobicContact CG1-CG2 3.81Å
389	P	86.9	Confident	93.5	Very high	107 Å²	107	39.4 Å²	39.4	70%	0.695	22%	0.215	S	C	*	.			trans	-80	-24.2	-174.6	30.7	-35.1	0	0	0	113.2	F137 F387	F137-P389 WeakPolarHBondContact CE2-O 3.4Å; F137-P389 WeakPolarHBondContact CZ-O 3.35Å; F387-P389 WeakPolarHBondContact O-CD 3.37Å
390	D	89.8	Confident	93.4	Very high	25 Å²	25	38 Å²	38	13%	0.134	20%	0.2	C	C	.	.			trans	-139.5	129.4	-174.2	-168	-21.7	0	0	0	111.5	S313 V388 R392 N393	S313-D390 WeakPolarHBondContact CB-OD1 3.22Å; S313-D390 PolarHBondContact OG-OD1 3.4Å; V388-D390 WeakPolarHBondContact CG1-O 3.15Å; D390-R392 PolarHBondContact O-N 3.19Å; D390-R392 WeakPolarHBondContact OD1-CB 3.37Å; D390-R392 PolarHBondContact OD1-N 3.22Å; D390-R392 IonicContact OD1-NE 3.03Å; D390-R392 IonicContact OD2-CZ 3.15Å; D390-R392 IonicContact OD2-NE 2.83Å; D390-R392 PolarHBondContact OD2-NE 3.44Å; D390-R392 IonicContact OD2-NH2 2.66Å; D390-R392 PolarHBondContact OD2-NH2 3.39Å; D390-N393 WeakPolarHBondContact O-CB 3.49Å; D390-N393 PolarHBondContact O-N 3.38Å; D390-N393 VanDerWaalsContact O-N 3.14Å
391	I	90.4	Very high	93.4	Very high	0 Å²	0	36.4 Å²	36.4	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-59.9	-28.7	176.9	-160.6	171.7	0	0	0	112.9	F137 I138 E314 N393 V394 F395	F137-I391 HydrophobicContact CD1-CB 3.74Å; F137-I391 HydrophobicContact CD1-CD1 4.15Å; F137-I391 HydrophobicContact CD1-CG1 4.24Å; F137-I391 HydrophobicContact CE1-CB 3.89Å; F137-I391 HydrophobicContact CE1-CG2 4.38Å; F137-I391 HydrophobicContact CG-CB 4.2Å; F137-I391 HydrophobicContact CZ-CB 4.46Å; I138-I391 HydrophobicContact CD1-CD1 4.31Å; I138-I391 HydrophobicContact CG1-CD1 3.99Å; E314-I391 HydrophobicContact CB-CG2 4.33Å; I391-N393 PolarHBondContact O-N 3.21Å; I391-V394 WeakPolarHBondContact O-CB 3.16Å; I391-V394 PolarHBondContact O-N 3.32Å; I391-V394 VanDerWaalsContact O-N 3.11Å; I391-F395 HydrophobicContact CD1-CE1 4.16Å; I391-F395 HydrophobicContact CD1-CE2 3.91Å; I391-F395 HydrophobicContact CD1-CZ 3.45Å; I391-F395 VanDerWaalsContact CD1-CZ 3.45Å; I391-F395 HydrophobicContact CG1-CD1 4.5Å; I391-F395 HydrophobicContact CG1-CD2 4.37Å; I391-F395 HydrophobicContact CG1-CE1 3.92Å; I391-F395 HydrophobicContact CG1-CE2 3.78Å; I391-F395 HydrophobicContact CG1-CZ 3.53Å; I391-F395 HydrophobicContact CG2-CE2 4.31Å; I391-F395 PolarHBondContact O-N 3.45Å
392	R	91.6	Very high	93.3	Very high	70 Å²	70	38 Å²	38	26%	0.264	20%	0.199	S	C	.	.	H	α-helix	trans	-58	-34.8	175.3	-78.3	178	-53.4	175	1	112.8	Y64 Y251 S313 D390 V394 F395 G396	Y64-R392 HydrophobicContact CD1-CG 4.13Å; Y64-R392 HydrophobicContact CE1-CG 4.16Å; Y64-R392 VanDerWaalsContact CE2-NH1 3.27Å; Y64-R392 VanDerWaalsContact CZ-CD 3.45Å; Y64-R392 PolarHBondContact OH-NH1 3.48Å; Y251-R392 HydrophobicContact CD1-CB 4.47Å; S313-R392 VanDerWaalsContact CB-CD 3.44Å; D390-R392 PolarHBondContact O-N 3.19Å; D390-R392 WeakPolarHBondContact OD1-CB 3.37Å; D390-R392 PolarHBondContact OD1-N 3.22Å; D390-R392 IonicContact OD1-NE 3.03Å; D390-R392 IonicContact OD2-CZ 3.15Å; D390-R392 IonicContact OD2-NE 2.83Å; D390-R392 PolarHBondContact OD2-NE 3.44Å; D390-R392 IonicContact OD2-NH2 2.66Å; D390-R392 PolarHBondContact OD2-NH2 3.39Å; R392-V394 VanDerWaalsContact C-N 3.34Å; R392-F395 PolarHBondContact O-N 2.89Å; R392-G396 PolarHBondContact O-N 2.82Å
393	N	92.3	Very high	93.3	Very high	37 Å²	37	36.6 Å²	36.6	20%	0.198	19%	0.191	C	C	.	.	H	α-helix	trans	-68.7	-37.9	179.9	-69.9	-25.8	0	0	0	110.8	V388 D390 I391 G396 V397 W453	V388-N393 HydrophobicContact CG1-CB 4.43Å; D390-N393 WeakPolarHBondContact O-CB 3.49Å; D390-N393 PolarHBondContact O-N 3.38Å; D390-N393 VanDerWaalsContact O-N 3.14Å; I391-N393 PolarHBondContact O-N 3.21Å; N393-G396 PolarHBondContact O-N 3.41Å; N393-V397 WeakPolarHBondContact O-CB 3.48Å; N393-V397 VanDerWaalsContact O-CG2 3.3Å; N393-V397 WeakPolarHBondContact O-CG2 3.45Å; N393-V397 PolarHBondContact O-N 2.82Å; N393-W453 HydrophobicContact CB-CZ2 4.03Å; N393-W453 PolarHBondContact OD1-NE1 2.99Å
394	V	93.3	Very high	93.3	Very high	14 Å²	14	31.5 Å²	31.5	9%	0.085	17%	0.166	C	C	.	.	H	α-helix	trans	-62.9	-51.6	173.8	-175	0	0	0	0	110.1	G130 S133 V388 I391 R392 G396 V398	G130-V394 WeakPolarHBondContact O-CG1 3.4Å; S133-V394 WeakPolarHBondContact OG-CG1 3.31Å; V388-V394 HydrophobicContact CB-CG2 4.49Å; V388-V394 HydrophobicContact CG1-CG2 3.81Å; I391-V394 WeakPolarHBondContact O-CB 3.16Å; I391-V394 PolarHBondContact O-N 3.32Å; I391-V394 VanDerWaalsContact O-N 3.11Å; R392-V394 VanDerWaalsContact C-N 3.34Å; V394-G396 VanDerWaalsContact C-N 3.32Å; V394-G396 PolarHBondContact O-N 3.41Å; V394-V398 HydrophobicContact CG1-CG2 4.17Å; V394-V398 VanDerWaalsContact O-CB 3.26Å; V394-V398 WeakPolarHBondContact O-CB 3.37Å; V394-V398 WeakPolarHBondContact O-CG2 3.18Å; V394-V398 PolarHBondContact O-N 2.86Å
395	F	92.9	Very high	93.4	Very high	1 Å²	1	30 Å²	30	0%	0.004	16%	0.161	C	C	.	.	H	α-helix	trans	-61.8	-39.3	179	-63.2	-20.2	0	0	0	112.6	S57 S134 T255 F258 I391 R392 G399	S57-F395 WeakPolarHBondContact O-CZ 3.41Å; S134-F395 VanDerWaalsContact CB-CE1 3.47Å; T255-F395 HydrophobicContact CG2-CB 4.33Å; T255-F395 HydrophobicContact CG2-CD2 3.98Å; T255-F395 HydrophobicContact CG2-CG 4.41Å; F258-F395 AromaticContact CD1-CD1 3.62Å; F258-F395 HydrophobicContact CD1-CD1 3.62Å; F258-F395 AromaticContact CD1-CE1 3.89Å; F258-F395 HydrophobicContact CD1-CE1 3.89Å; F258-F395 HydrophobicContact CD1-CG 4.41Å; F258-F395 AromaticContact CE1-CD1 3.45Å; F258-F395 HydrophobicContact CE1-CD1 3.45Å; F258-F395 VanDerWaalsContact CE1-CD1 3.45Å; F258-F395 AromaticContact CE1-CE1 3.35Å; F258-F395 HydrophobicContact CE1-CE1 3.35Å; F258-F395 HydrophobicContact CE1-CZ 4.42Å; F258-F395 HydrophobicContact CE2-CD1 4.48Å; F258-F395 HydrophobicContact CG-CD1 4.21Å; F258-F395 AromaticContact CZ-CD1 3.89Å; F258-F395 HydrophobicContact CZ-CD1 3.89Å; F258-F395 AromaticContact CZ-CE1 3.91Å; F258-F395 HydrophobicContact CZ-CE1 3.91Å; I391-F395 HydrophobicContact CD1-CE1 4.16Å; I391-F395 HydrophobicContact CD1-CE2 3.91Å; I391-F395 HydrophobicContact CD1-CZ 3.45Å; I391-F395 VanDerWaalsContact CD1-CZ 3.45Å; I391-F395 HydrophobicContact CG1-CD1 4.5Å; I391-F395 HydrophobicContact CG1-CD2 4.37Å; I391-F395 HydrophobicContact CG1-CE1 3.92Å; I391-F395 HydrophobicContact CG1-CE2 3.78Å; I391-F395 HydrophobicContact CG1-CZ 3.53Å; I391-F395 HydrophobicContact CG2-CE2 4.31Å; I391-F395 PolarHBondContact O-N 3.45Å; R392-F395 PolarHBondContact O-N 2.89Å; F395-G399 WeakPolarHBondContact O-CA 3.29Å; F395-G399 PolarHBondContact O-N 3.44Å
396	G	92.9	Very high	93.5	Very high	0 Å²	0	30 Å²	30	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-63.6	-55.8	177.5	0	0	0	0	0	112.5	R392 N393 V394 S400 I449	R392-G396 PolarHBondContact O-N 2.82Å; N393-G396 PolarHBondContact O-N 3.41Å; V394-G396 VanDerWaalsContact C-N 3.32Å; V394-G396 PolarHBondContact O-N 3.41Å; G396-S400 WeakPolarHBondContact O-CB 3.41Å; G396-S400 PolarHBondContact O-N 2.86Å; G396-S400 PolarHBondContact O-OG 3.23Å; G396-I449 WeakPolarHBondContact O-CD1 3.49Å
397	V	95	Very high	93.6	Very high	46 Å²	46	28.8 Å²	28.8	28%	0.279	15%	0.154	S	C	.	.	H	α-helix	trans	-70.3	-52.4	-175.6	176.5	0	0	0	0	111.5	N393 G399 S400 T401 I449 W453	N393-V397 WeakPolarHBondContact O-CB 3.48Å; N393-V397 VanDerWaalsContact O-CG2 3.3Å; N393-V397 WeakPolarHBondContact O-CG2 3.45Å; N393-V397 PolarHBondContact O-N 2.82Å; V397-G399 VanDerWaalsContact C-N 3.31Å; V397-G399 PolarHBondContact O-N 3.05Å; V397-S400 PolarHBondContact O-N 3.37Å; V397-S400 PolarHBondContact O-OG 3.04Å; V397-T401 WeakPolarHBondContact O-CB 3.33Å; V397-T401 WeakPolarHBondContact O-CG2 3.21Å; V397-T401 PolarHBondContact O-N 3.43Å; V397-T401 PolarHBondContact O-OG1 3.28Å; V397-I449 HydrophobicContact CG2-CG2 4.45Å; V397-W453 HydrophobicContact CG2-CH2 3.36Å; V397-W453 HydrophobicContact CG2-CZ2 3.74Å; V397-W453 HydrophobicContact CG2-CZ3 4.44Å
398	V	95.8	Very high	93.7	Very high	14 Å²	14	21.6 Å²	21.6	9%	0.085	12%	0.123	C	C	.	.	H	α-helix	trans	-68.5	-37.6	-176.6	-178.6	0	0	0	0	110	F258 V394 M402 S403	F258-V398 HydrophobicContact CD2-CB 4.21Å; F258-V398 HydrophobicContact CD2-CG1 3.94Å; F258-V398 HydrophobicContact CE2-CB 4.26Å; F258-V398 HydrophobicContact CE2-CG1 3.9Å; V394-V398 HydrophobicContact CG1-CG2 4.17Å; V394-V398 VanDerWaalsContact O-CB 3.26Å; V394-V398 WeakPolarHBondContact O-CB 3.37Å; V394-V398 WeakPolarHBondContact O-CG2 3.18Å; V394-V398 PolarHBondContact O-N 2.86Å; V398-M402 HydrophobicContact CG1-CB 4.3Å; V398-M402 PolarHBondContact O-N 2.92Å; V398-S403 PolarHBondContact O-N 3.34Å; V398-S403 PolarHBondContact O-OG 3.39Å
399	G	94.7	Very high	94.1	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	12%	0.117	C	C	.	.	I	π-helix	trans	-64	-46.3	175.7	0	0	0	0	0	113.8	P254 F395 V397 T401 S403 S404	P254-G399 WeakPolarHBondContact O-CA 3.4Å; F395-G399 WeakPolarHBondContact O-CA 3.29Å; F395-G399 PolarHBondContact O-N 3.44Å; V397-G399 VanDerWaalsContact C-N 3.31Å; V397-G399 PolarHBondContact O-N 3.05Å; G399-T401 VanDerWaalsContact C-N 3.35Å; G399-S403 WeakPolarHBondContact O-CB 3.49Å; G399-S404 PolarHBondContact O-N 3.27Å
400	S	95.3	Very high	94.6	Very high	2 Å²	2	16 Å²	16	1%	0.014	9%	0.086	C	C	.	.	I	π-helix	trans	-72.9	-28.4	-178.6	57.2	0	0	0	0	112.8	G396 V397 S404 G442	G396-S400 WeakPolarHBondContact O-CB 3.41Å; G396-S400 PolarHBondContact O-N 2.86Å; G396-S400 PolarHBondContact O-OG 3.23Å; V397-S400 PolarHBondContact O-N 3.37Å; V397-S400 PolarHBondContact O-OG 3.04Å; S400-S404 WeakPolarHBondContact O-CB 3.3Å; S400-G442 WeakPolarHBondContact O-CA 3.32Å
401	T	96.1	Very high	94.9	Very high	34 Å²	34	14.8 Å²	14.8	21%	0.209	8%	0.08	C	C	.	.	I	π-helix	trans	-97.8	-79.7	-178.5	60.2	0	0	0	0	111.6	V397 G399 S404 C405 L446	V397-T401 WeakPolarHBondContact O-CB 3.33Å; V397-T401 WeakPolarHBondContact O-CG2 3.21Å; V397-T401 PolarHBondContact O-N 3.43Å; V397-T401 PolarHBondContact O-OG1 3.28Å; G399-T401 VanDerWaalsContact C-N 3.35Å; T401-S404 PolarHBondContact O-N 3.22Å; T401-C405 WeakPolarHBondContact O-CB 3.37Å; T401-C405 PolarHBondContact O-N 3.3Å; T401-C405 PolarHBondContact O-SG 2.9Å; T401-L446 HydrophobicContact CG2-CD1 4.03Å; T401-L446 HydrophobicContact CG2-CD2 3.9Å; T401-L446 HydrophobicContact CG2-CG 4.48Å
402	M	95.8	Very high	95.2	Very high	34 Å²	34	14.8 Å²	14.8	17%	0.167	8%	0.08	C	C	.	.	I	π-helix	trans	-71.2	-43.5	-169.5	-58	-59	98.4	0	0	112.2	A123 I126 Q127 V398 C405 L406	A123-M402 HydrophobicContact CB-SD 4.01Å; I126-M402 HydrophobicContact CB-CG 3.76Å; I126-M402 HydrophobicContact CB-SD 3.82Å; I126-M402 HydrophobicContact CD1-SD 3.93Å; I126-M402 HydrophobicContact CG1-SD 4.45Å; I126-M402 HydrophobicContact CG2-CG 3.47Å; I126-M402 VanDerWaalsContact CG2-CG 3.47Å; I126-M402 HydrophobicContact CG2-SD 3.95Å; Q127-M402 HydrophobicContact CB-CB 4.03Å; V398-M402 HydrophobicContact CG1-CB 4.3Å; V398-M402 PolarHBondContact O-N 2.92Å; M402-C405 PolarHBondContact O-N 3.37Å; M402-L406 WeakPolarHBondContact O-CB 3.3Å; M402-L406 WeakPolarHBondContact O-CG 3.24Å; M402-L406 PolarHBondContact O-N 3.28Å
403	S	95.1	Very high	95.4	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	8%	0.079	C	C	.	.	I	π-helix	trans	-67	-39.9	177.5	-46.9	0	0	0	0	110.8	Q127 F258 V398 G399 C405 L406 L407	Q127-S403 PolarHBondContact NE2-OG 2.91Å; Q127-S403 VanDerWaalsContact OE1-N 3.16Å; Q127-S403 PolarHBondContact OE1-OG 2.97Å; F258-S403 WeakPolarHBondContact CA-OG 3.33Å; V398-S403 PolarHBondContact O-N 3.34Å; V398-S403 PolarHBondContact O-OG 3.39Å; G399-S403 WeakPolarHBondContact O-CB 3.49Å; S403-C405 VanDerWaalsContact C-N 3.33Å; S403-C405 PolarHBondContact O-N 3.48Å; S403-L406 PolarHBondContact O-N 3.08Å; S403-L407 WeakPolarHBondContact O-CA 3.43Å; S403-L407 WeakPolarHBondContact O-CB 3.33Å; S403-L407 PolarHBondContact O-N 3.47Å
404	S	95.5	Very high	95.6	Very high	3 Å²	3	12 Å²	12	2%	0.021	7%	0.069	C	C	.	.	H	α-helix	trans	-58.7	-44.3	173.3	-170	0	0	0	0	112.3	G399 S400 T401 F408 V409 G438 M441	G399-S404 PolarHBondContact O-N 3.27Å; S400-S404 WeakPolarHBondContact O-CB 3.3Å; T401-S404 PolarHBondContact O-N 3.22Å; S404-F408 WeakPolarHBondContact O-CA 3.39Å; S404-F408 WeakPolarHBondContact O-CB 3.19Å; S404-F408 PolarHBondContact O-N 3.22Å; S404-V409 PolarHBondContact O-N 3.09Å; S404-V409 VanDerWaalsContact O-N 3.12Å; S404-G438 WeakPolarHBondContact OG-CA 3.22Å; S404-G438 PolarHBondContact OG-O 3.49Å; S404-M441 WeakPolarHBondContact OG-CE 3.4Å
405	C	96.6	Very high	95.8	Very high	36 Å²	36	11.3 Å²	11.3	24%	0.243	7%	0.065	C	C	.	.	I	π-helix	trans	-64	-49.4	177.7	-72.1	0	0	0	0	112.6	T401 M402 S403 V409 F410	T401-C405 WeakPolarHBondContact O-CB 3.37Å; T401-C405 PolarHBondContact O-N 3.3Å; T401-C405 PolarHBondContact O-SG 2.9Å; M402-C405 PolarHBondContact O-N 3.37Å; S403-C405 VanDerWaalsContact C-N 3.33Å; S403-C405 PolarHBondContact O-N 3.48Å; C405-V409 PolarHBondContact O-N 3.45Å; C405-F410 HydrophobicContact CB-CD2 4.33Å; C405-F410 HydrophobicContact CB-CE1 4.4Å; C405-F410 HydrophobicContact CB-CE2 3.89Å; C405-F410 HydrophobicContact CB-CZ 3.91Å; C405-F410 WeakPolarHBondContact O-CB 3.41Å; C405-F410 WeakPolarHBondContact O-CD2 3.16Å; C405-F410 WeakPolarHBondContact O-CG 3.3Å; C405-F410 PolarHBondContact O-N 3.31Å
406	L	96.5	Very high	95.9	Very high	0 Å²	0	14.4 Å²	14.4	0%	0	8%	0.081	C	C	.	.	I	π-helix	trans	-74.4	-32.7	-175.9	-70	164.9	0	0	0	113.3	Y104 A123 I124 Q127 L261 T264 M402 S403 F410 P411	Y104-L406 HydrophobicContact CE1-CD2 3.92Å; Y104-L406 PolarHBondContact OH-O 2.94Å; A123-L406 HydrophobicContact CB-CD1 4.39Å; A123-L406 HydrophobicContact CB-CD2 4.18Å; A123-L406 HydrophobicContact CB-CG 4.18Å; I124-L406 HydrophobicContact CG1-CD2 3.89Å; Q127-L406 HydrophobicContact CB-CD1 3.82Å; Q127-L406 HydrophobicContact CG-CD1 4.03Å; L261-L406 HydrophobicContact CD1-CB 3.68Å; L261-L406 HydrophobicContact CD2-CB 4.44Å; L261-L406 HydrophobicContact CD2-CD1 4.05Å; T264-L406 HydrophobicContact CG2-CD1 4.03Å; M402-L406 WeakPolarHBondContact O-CB 3.3Å; M402-L406 WeakPolarHBondContact O-CG 3.24Å; M402-L406 PolarHBondContact O-N 3.28Å; S403-L406 PolarHBondContact O-N 3.08Å; L406-F410 HydrophobicContact CD2-CD2 3.92Å; L406-F410 HydrophobicContact CD2-CE2 4.11Å; L406-F410 HydrophobicContact CG-CD2 4.42Å; L406-F410 HydrophobicContact CG-CE2 4.48Å; L406-P411 WeakPolarHBondContact O-CD 3.42Å; L406-P411 WeakPolarHBondContact O-CG 3.4Å
407	L	95.8	Very high	96	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	11%	0.112	C	C	.	.	I	π-helix	trans	-87	-37.3	-177.2	-156	149.2	0	0	0	111.4	A85 S88 A257 F260 L261 S403	A85-L407 HydrophobicContact CB-CD1 4.33Å; A85-L407 HydrophobicContact CB-CD2 3.97Å; A85-L407 HydrophobicContact CB-CG 4.38Å; S88-L407 WeakPolarHBondContact CB-O 3.2Å; S88-L407 PolarHBondContact OG-O 2.97Å; A257-L407 WeakPolarHBondContact O-CD1 3.36Å; F260-L407 HydrophobicContact CB-CD1 4.3Å; L261-L407 HydrophobicContact CB-CD1 4.25Å; L261-L407 HydrophobicContact CD1-CB 3.81Å; L261-L407 HydrophobicContact CD1-CD1 4.13Å; L261-L407 HydrophobicContact CD1-CG 4.31Å; S403-L407 WeakPolarHBondContact O-CA 3.43Å; S403-L407 WeakPolarHBondContact O-CB 3.33Å; S403-L407 PolarHBondContact O-N 3.47Å
408	F	95.8	Very high	95.9	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	11%	0.105	C	C	.	.	I	π-helix	trans	-115.4	-64.5	-175.9	-47.9	-63.8	0	0	0	112.1	V81 L84 A257 S404 F410 P411 G412 L434 F437 M441	V81-F408 HydrophobicContact CG1-CZ 4.47Å; L84-F408 HydrophobicContact CB-CD1 4.16Å; L84-F408 HydrophobicContact CB-CE1 3.61Å; L84-F408 HydrophobicContact CD1-CD1 4.29Å; L84-F408 HydrophobicContact CD1-CE1 3.71Å; L84-F408 HydrophobicContact CD1-CZ 4.47Å; L84-F408 HydrophobicContact CG-CE1 4.29Å; A257-F408 HydrophobicContact CB-CE2 4.08Å; A257-F408 HydrophobicContact CB-CZ 4.45Å; S404-F408 WeakPolarHBondContact O-CA 3.39Å; S404-F408 WeakPolarHBondContact O-CB 3.19Å; S404-F408 PolarHBondContact O-N 3.22Å; F408-F410 PolarHBondContact O-N 3.01Å; F408-P411 WeakPolarHBondContact O-CD 3.28Å; F408-G412 PolarHBondContact O-N 2.83Å; F408-L434 HydrophobicContact CB-CD2 4.47Å; F408-L434 HydrophobicContact CB-CG 4.23Å; F408-L434 WeakPolarHBondContact CB-O 3.34Å; F408-L434 HydrophobicContact CD1-CG 4.39Å; F408-L434 WeakPolarHBondContact O-CD2 3.37Å; F408-F437 HydrophobicContact CD1-CD1 4.17Å; F408-F437 HydrophobicContact CD1-CE1 4.45Å; F408-F437 HydrophobicContact CD2-CD1 4.4Å; F408-F437 HydrophobicContact CD2-CE1 4.49Å; F408-F437 HydrophobicContact CE1-CD1 4.14Å; F408-F437 AromaticContact CE1-CE1 3.97Å; F408-F437 HydrophobicContact CE1-CE1 3.97Å; F408-F437 HydrophobicContact CE2-CD1 4.45Å; F408-F437 HydrophobicContact CE2-CE1 4.1Å; F408-F437 HydrophobicContact CG-CD1 4.29Å; F408-F437 HydrophobicContact CZ-CD1 4.29Å; F408-F437 AromaticContact CZ-CE1 3.78Å; F408-F437 HydrophobicContact CZ-CE1 3.78Å; F408-M441 HydrophobicContact CD2-CE 3.83Å; F408-M441 HydrophobicContact CE2-CE 3.36Å; F408-M441 HydrophobicContact CZ-CE 4.44Å
409	V	97.5	Very high	95.7	Very high	10 Å²	10	20.5 Å²	20.5	6%	0.061	11%	0.106	C	C	.	.	I	π-helix	trans	-63.6	-47	-164.7	-177.6	0	0	0	0	113.5	S404 C405 I413 V435 L439	S404-V409 PolarHBondContact O-N 3.09Å; S404-V409 VanDerWaalsContact O-N 3.12Å; C405-V409 PolarHBondContact O-N 3.45Å; V409-I413 HydrophobicContact CG1-CD1 3.58Å; V409-I413 HydrophobicContact CG1-CG1 4.34Å; V409-I413 VanDerWaalsContact O-CG1 3.31Å; V409-I413 WeakPolarHBondContact O-CG1 3.39Å; V409-I413 PolarHBondContact O-N 3.28Å; V409-V435 HydrophobicContact CG1-CG1 4.48Å; V409-L439 HydrophobicContact CG1-CD2 4.48Å; V409-L439 HydrophobicContact CG2-CD2 4.14Å; V409-L439 HydrophobicContact CG2-CG 4.18Å
410	F	97.1	Very high	95.1	Very high	10 Å²	10	26.4 Å²	26.4	4%	0.044	15%	0.147	C	C	.	.	H	α-helix	trans	-68.8	-48.9	-174.2	-65.5	-27.7	0	0	0	113.9	Y104 L119 V120 A123 C405 L406 F408 G412 I413 F414	Y104-F410 HydrophobicContact CE1-CB 4.11Å; Y104-F410 HydrophobicContact CE1-CD2 4.12Å; L119-F410 HydrophobicContact CD2-CE1 3.8Å; L119-F410 HydrophobicContact CD2-CZ 4.01Å; L119-F410 HydrophobicContact CG-CE1 4.19Å; L119-F410 HydrophobicContact CG-CZ 3.88Å; V120-F410 HydrophobicContact CG2-CD2 4.18Å; V120-F410 HydrophobicContact CG2-CE2 4.22Å; A123-F410 HydrophobicContact CB-CE2 3.76Å; A123-F410 HydrophobicContact CB-CZ 4.32Å; C405-F410 HydrophobicContact CB-CD2 4.33Å; C405-F410 HydrophobicContact CB-CE1 4.4Å; C405-F410 HydrophobicContact CB-CE2 3.89Å; C405-F410 HydrophobicContact CB-CZ 3.91Å; C405-F410 WeakPolarHBondContact O-CB 3.41Å; C405-F410 WeakPolarHBondContact O-CD2 3.16Å; C405-F410 WeakPolarHBondContact O-CG 3.3Å; C405-F410 PolarHBondContact O-N 3.31Å; L406-F410 HydrophobicContact CD2-CD2 3.92Å; L406-F410 HydrophobicContact CD2-CE2 4.11Å; L406-F410 HydrophobicContact CG-CD2 4.42Å; L406-F410 HydrophobicContact CG-CE2 4.48Å; F408-F410 PolarHBondContact O-N 3.01Å; F410-G412 VanDerWaalsContact C-N 3.25Å; F410-G412 PolarHBondContact O-N 2.81Å; F410-I413 PolarHBondContact O-N 2.64Å; F410-F414 HydrophobicContact CB-CD2 4.41Å; F410-F414 HydrophobicContact CB-CE1 4.23Å; F410-F414 HydrophobicContact CB-CE2 3.82Å; F410-F414 HydrophobicContact CB-CZ 3.69Å; F410-F414 HydrophobicContact CG-CZ 4.1Å; F410-F414 WeakPolarHBondContact O-CB 3.47Å; F410-F414 WeakPolarHBondContact O-CD1 3.38Å; F410-F414 WeakPolarHBondContact O-CD2 3.48Å; F410-F414 WeakPolarHBondContact O-CG 3.28Å; F410-F414 PolarHBondContact O-N 2.96Å
411	P	96.6	Very high	94.6	Very high	0 Å²	0	31 Å²	31	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-60.4	-37.3	-179.8	-30.1	43.4	0	0	0	112.3	S88 Y104 L406 F408 Y415	S88-P411 WeakPolarHBondContact OG-CB 3.14Å; S88-P411 WeakPolarHBondContact OG-CG 3.33Å; Y104-P411 VanDerWaalsContact OH-CD 3.31Å; Y104-P411 WeakPolarHBondContact OH-CD 3.23Å; Y104-P411 VanDerWaalsContact OH-CG 3.25Å; Y104-P411 WeakPolarHBondContact OH-CG 3.42Å; L406-P411 WeakPolarHBondContact O-CD 3.42Å; L406-P411 WeakPolarHBondContact O-CG 3.4Å; F408-P411 WeakPolarHBondContact O-CD 3.28Å; P411-Y415 WeakPolarHBondContact O-CB 3.3Å; P411-Y415 PolarHBondContact O-N 2.66Å
412	G	96.3	Very high	94	Very high	0 Å²	0	33.3 Å²	33.3	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-65.4	-46.9	174.3	0	0	0	0	0	113.2	F408 F410 F414 Y415 L416	F408-G412 PolarHBondContact O-N 2.83Å; F410-G412 VanDerWaalsContact C-N 3.25Å; F410-G412 PolarHBondContact O-N 2.81Å; G412-F414 PolarHBondContact O-N 2.63Å; G412-Y415 PolarHBondContact O-N 3.12Å; G412-L416 VanDerWaalsContact O-CG 3.28Å; G412-L416 WeakPolarHBondContact O-CG 3.27Å; G412-L416 PolarHBondContact O-N 3.47Å
413	I	96.8	Very high	93.2	Very high	47 Å²	47	37.8 Å²	37.8	24%	0.241	21%	0.207	C	C	.	.	H	α-helix	trans	-62.4	-43.8	176.6	-70.3	174.6	0	0	0	111.3	L112 V409 F410 Y415 L416 K417 V435	L112-I413 HydrophobicContact CD1-CG2 4.22Å; L112-I413 HydrophobicContact CD2-CG2 4.18Å; L112-I413 HydrophobicContact CG-CG2 4.38Å; V409-I413 HydrophobicContact CG1-CD1 3.58Å; V409-I413 HydrophobicContact CG1-CG1 4.34Å; V409-I413 VanDerWaalsContact O-CG1 3.31Å; V409-I413 WeakPolarHBondContact O-CG1 3.39Å; V409-I413 PolarHBondContact O-N 3.28Å; F410-I413 PolarHBondContact O-N 2.64Å; I413-Y415 VanDerWaalsContact C-N 3.32Å; I413-Y415 PolarHBondContact O-N 3.15Å; I413-L416 PolarHBondContact O-N 3.47Å; I413-K417 HydrophobicContact CG2-CG 4.38Å; I413-K417 WeakPolarHBondContact O-CB 3.27Å; I413-K417 WeakPolarHBondContact O-CG 3.46Å; I413-K417 PolarHBondContact O-N 2.86Å; I413-V435 HydrophobicContact CG1-CG1 4.48Å; I413-V435 HydrophobicContact CG1-CG2 3.91Å
414	F	96.6	Very high	92.6	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-62.5	-43.4	179.8	-61.6	-14.7	0	0	0	110.7	L95 Y104 L107 A111 V120 F410 G412 L416 K417 I418	L95-F414 HydrophobicContact CD1-CB 3.66Å; Y104-F414 HydrophobicContact CD1-CE2 4.01Å; Y104-F414 AromaticContact CE1-CE2 3.62Å; Y104-F414 HydrophobicContact CE1-CE2 3.62Å; Y104-F414 HydrophobicContact CE1-CZ 4.28Å; L107-F414 HydrophobicContact CB-CD2 4.29Å; L107-F414 HydrophobicContact CB-CE2 4.46Å; L107-F414 HydrophobicContact CD2-CB 4.19Å; L107-F414 HydrophobicContact CD2-CD2 3.63Å; L107-F414 HydrophobicContact CD2-CE2 4.41Å; L107-F414 HydrophobicContact CD2-CG 4.26Å; L107-F414 HydrophobicContact CG-CB 4.27Å; L107-F414 HydrophobicContact CG-CD2 3.87Å; L107-F414 HydrophobicContact CG-CG 4.22Å; A111-F414 HydrophobicContact CB-CB 4.48Å; A111-F414 HydrophobicContact CB-CD1 3.51Å; A111-F414 HydrophobicContact CB-CE1 4.17Å; A111-F414 HydrophobicContact CB-CG 4.29Å; V120-F414 HydrophobicContact CG2-CE1 4.45Å; V120-F414 HydrophobicContact CG2-CE2 4.38Å; V120-F414 HydrophobicContact CG2-CZ 3.56Å; F410-F414 HydrophobicContact CB-CD2 4.41Å; F410-F414 HydrophobicContact CB-CE1 4.23Å; F410-F414 HydrophobicContact CB-CE2 3.82Å; F410-F414 HydrophobicContact CB-CZ 3.69Å; F410-F414 HydrophobicContact CG-CZ 4.1Å; F410-F414 WeakPolarHBondContact O-CB 3.47Å; F410-F414 WeakPolarHBondContact O-CD1 3.38Å; F410-F414 WeakPolarHBondContact O-CD2 3.48Å; F410-F414 WeakPolarHBondContact O-CG 3.28Å; F410-F414 PolarHBondContact O-N 2.96Å; G412-F414 PolarHBondContact O-N 2.63Å; F414-L416 PolarHBondContact O-N 2.82Å; F414-K417 PolarHBondContact O-N 3.3Å; F414-I418 HydrophobicContact CB-CD1 4.36Å; F414-I418 VanDerWaalsContact O-CB 3.26Å; F414-I418 WeakPolarHBondContact O-CB 3.3Å; F414-I418 WeakPolarHBondContact O-CG1 3.22Å; F414-I418 PolarHBondContact O-N 3.05Å
415	Y	96.3	Very high	92.3	Very high	1 Å²	1	47.7 Å²	47.7	0%	0.004	25%	0.253	C	S	.	.	H	α-helix	trans	-61.2	-48.1	178.4	-170.6	-97.6	0	0	0	111.8	L91 T94 L95 P411 G412 I413 K417 S419 D427 A431	L91-Y415 HydrophobicContact CB-CD2 4.24Å; L91-Y415 HydrophobicContact CB-CG 4.45Å; L91-Y415 HydrophobicContact CD1-CG 4.48Å; L91-Y415 HydrophobicContact CD2-CD1 4.09Å; L91-Y415 HydrophobicContact CD2-CD2 3.72Å; L91-Y415 HydrophobicContact CD2-CE1 4.32Å; L91-Y415 HydrophobicContact CD2-CE2 3.97Å; L91-Y415 HydrophobicContact CD2-CG 3.78Å; L91-Y415 HydrophobicContact CG-CD2 4.5Å; L91-Y415 HydrophobicContact CG-CG 4.46Å; T94-Y415 HydrophobicContact CG2-CE2 4.18Å; L95-Y415 HydrophobicContact CD1-CD2 4.49Å; L95-Y415 HydrophobicContact CD2-CD2 4.02Å; L95-Y415 HydrophobicContact CG-CD2 4.13Å; P411-Y415 WeakPolarHBondContact O-CB 3.3Å; P411-Y415 PolarHBondContact O-N 2.66Å; G412-Y415 PolarHBondContact O-N 3.12Å; I413-Y415 VanDerWaalsContact C-N 3.32Å; I413-Y415 PolarHBondContact O-N 3.15Å; Y415-K417 VanDerWaalsContact C-N 3.26Å; Y415-K417 PolarHBondContact O-N 3.47Å; Y415-S419 WeakPolarHBondContact O-CB 3.48Å; Y415-S419 PolarHBondContact O-N 3.42Å; Y415-S419 PolarHBondContact OH-OG 2.91Å; Y415-D427 HydrophobicContact CE1-CB 3.59Å; Y415-D427 HydrophobicContact CE2-CB 4.46Å; Y415-D427 VanDerWaalsContact OH-CB 3.23Å; Y415-D427 WeakPolarHBondContact OH-CB 3.39Å; Y415-A431 HydrophobicContact CD1-CB 3.86Å; Y415-A431 HydrophobicContact CG-CB 4.41Å
416	L	95.3	Very high	92	Very high	65 Å²	65	54 Å²	54	34%	0.34	28%	0.276	S	S	.	.	H	α-helix	trans	-65.9	-25.7	-179.7	-67.7	170.7	0	0	0	114	G412 I413 F414 A431 I432	G412-L416 VanDerWaalsContact O-CG 3.28Å; G412-L416 WeakPolarHBondContact O-CG 3.27Å; G412-L416 PolarHBondContact O-N 3.47Å; I413-L416 PolarHBondContact O-N 3.47Å; F414-L416 PolarHBondContact O-N 2.82Å; L416-A431 HydrophobicContact CD1-CB 4.38Å; L416-A431 HydrophobicContact CD2-CB 4.13Å; L416-A431 HydrophobicContact CG-CB 3.93Å; L416-I432 HydrophobicContact CD1-CG1 3.74Å; L416-I432 HydrophobicContact CD2-CD1 4.45Å; L416-I432 HydrophobicContact CD2-CG1 3.97Å; L416-I432 HydrophobicContact CG-CG1 4.5Å
417	K	94.4	Very high	91.8	Very high	146 Å²	146	56.1 Å²	56.1	64%	0.635	29%	0.288	S	S	*	.	H	α-helix	trans	-93.4	-30.5	-178.9	-75.4	-71.8	-176.5	-178.2	0	114	A111 I413 F414 Y415	A111-K417 HydrophobicContact CB-CB 4.09Å; I413-K417 HydrophobicContact CG2-CG 4.38Å; I413-K417 WeakPolarHBondContact O-CB 3.27Å; I413-K417 WeakPolarHBondContact O-CG 3.46Å; I413-K417 PolarHBondContact O-N 2.86Å; F414-K417 PolarHBondContact O-N 3.3Å; Y415-K417 VanDerWaalsContact C-N 3.26Å; Y415-K417 PolarHBondContact O-N 3.47Å
418	I	94.5	Very high	91.6	Very high	28 Å²	28	56.3 Å²	56.3	14%	0.144	29%	0.289	C	S	.	.	H	α-helix	trans	-103	-39.9	-171.7	-61.7	175.7	0	0	0	111.5	L95 T99 L107 K110 A111 F414	L95-I418 HydrophobicContact CD2-CB 3.84Å; L95-I418 HydrophobicContact CD2-CG2 3.83Å; T99-I418 HydrophobicContact CG2-CG2 3.4Å; T99-I418 VanDerWaalsContact CG2-CG2 3.4Å; L107-I418 HydrophobicContact CD1-CD1 3.42Å; L107-I418 VanDerWaalsContact CD1-CD1 3.42Å; L107-I418 HydrophobicContact CG-CD1 3.86Å; K110-I418 HydrophobicContact CB-CD1 4Å; K110-I418 HydrophobicContact CG-CD1 3.98Å; K110-I418 HydrophobicContact CG-CG1 4.23Å; A111-I418 HydrophobicContact CB-CD1 3.88Å; A111-I418 HydrophobicContact CB-CG1 3.99Å; F414-I418 HydrophobicContact CB-CD1 4.36Å; F414-I418 VanDerWaalsContact O-CB 3.26Å; F414-I418 WeakPolarHBondContact O-CB 3.3Å; F414-I418 WeakPolarHBondContact O-CG1 3.22Å; F414-I418 PolarHBondContact O-N 3.05Å
419	S	91.1	Very high	91.5	Very high	15 Å²	15	61 Å²	61	11%	0.105	31%	0.313	C	S	.	.			trans	-66.1	137.2	-176.5	-173.5	0	0	0	0	110.6	Y415 Q421	Y415-S419 WeakPolarHBondContact O-CB 3.48Å; Y415-S419 PolarHBondContact O-N 3.42Å; Y415-S419 PolarHBondContact OH-OG 2.91Å; S419-Q421 PolarHBondContact O-N 3.42Å; S419-Q421 WeakPolarHBondContact OG-CG 3.14Å; S419-Q421 PolarHBondContact OG-N 2.99Å
420	S	82	Confident	91.4	Very high	124 Å²	124	61.2 Å²	61.2	87%	0.867	32%	0.317	S	S	*	.			trans	-84.2	2.3	174.9	-57.3	0	0	0	0	113.1
421	Q	84.4	Confident	91.3	Very high	99 Å²	99	60.7 Å²	60.7	46%	0.463	32%	0.315	S	S	.	.	S	Bend	trans	-67.8	145.6	178.1	-69.2	-72.9	-5.9	0	0	111.2	S419	S419-Q421 PolarHBondContact O-N 3.42Å; S419-Q421 WeakPolarHBondContact OG-CG 3.14Å; S419-Q421 PolarHBondContact OG-N 2.99Å
422	P	83.8	Confident	91.3	Very high	82 Å²	82	64.2 Å²	64.2	53%	0.532	33%	0.333	S	S	.	.			trans	-64.7	147.9	178.5	27.9	-33.4	0	0	0	110.8	K424 S425 S428	P422-K424 PolarHBondContact O-N 2.67Å; P422-S425 WeakPolarHBondContact O-CB 3.43Å; P422-S425 PolarHBondContact O-N 3.08Å; P422-S425 PolarHBondContact O-OG 3.32Å; P422-S428 PolarHBondContact O-OG 3.35Å; P422-S428 VanDerWaalsContact O-OG 3.14Å
423	I	78.8	Confident	91.3	Very high	127 Å²	127	69.5 Å²	69.5	65%	0.651	36%	0.356	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.4	-24.6	-177.7	-59.1	170.8	0	0	0	112.5	S425 S428 I432	I423-S425 VanDerWaalsContact C-N 3.3Å; I423-S428 WeakPolarHBondContact O-CB 3.49Å; I423-I432 HydrophobicContact CG2-CD1 4.23Å
424	K	82.5	Confident	91.2	Very high	190 Å²	190	67.3 Å²	67.3	83%	0.826	35%	0.345	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.7	-2.5	176	-66	-174.4	178.6	-178.8	0	114	P422	P422-K424 PolarHBondContact O-N 2.67Å
425	S	90.6	Very high	91.3	Very high	21 Å²	21	68.3 Å²	68.3	15%	0.147	35%	0.351	C	S	.	.	S	Bend	trans	-64	150.4	174.7	72	0	0	0	0	110.4	P422 I423 D427 S428 I429	P422-S425 WeakPolarHBondContact O-CB 3.43Å; P422-S425 PolarHBondContact O-N 3.08Å; P422-S425 PolarHBondContact O-OG 3.32Å; I423-S425 VanDerWaalsContact C-N 3.3Å; S425-D427 PolarHBondContact O-N 3.38Å; S425-S428 PolarHBondContact O-N 2.85Å; S425-S428 VanDerWaalsContact O-N 3.11Å; S425-S428 WeakPolarHBondContact OG-CB 3.3Å; S425-S428 PolarHBondContact OG-N 3.41Å; S425-S428 VanDerWaalsContact OG-N 3.17Å; S425-S428 PolarHBondContact OG-OG 3.1Å; S425-I429 WeakPolarHBondContact O-CG1 3.35Å; S425-I429 PolarHBondContact O-N 3.05Å
426	F	89.9	Confident	91.3	Very high	169 Å²	169	71.7 Å²	71.7	74%	0.741	37%	0.372	S	S	*	.	H	α-helix	trans	-54.2	-40	177.7	-175.9	-97.7	0	0	0	111.5	I429 G430	F426-I429 PolarHBondContact O-N 3.04Å; F426-G430 PolarHBondContact O-N 3.12Å
427	D	90.8	Very high	91.3	Very high	45 Å²	45	70.4 Å²	70.4	24%	0.241	36%	0.363	C	S	.	.	H	α-helix	trans	-69.3	-36.8	179.6	-66.1	-26.9	0	0	0	113.3	Y87 L91 Y415 S425 A431	Y87-D427 VanDerWaalsContact OH-CA 3.28Å; Y87-D427 WeakPolarHBondContact OH-CA 3.33Å; Y87-D427 PolarHBondContact OH-O 3.45Å; L91-D427 HydrophobicContact CD2-CB 4.23Å; Y415-D427 HydrophobicContact CE1-CB 3.59Å; Y415-D427 HydrophobicContact CE2-CB 4.46Å; Y415-D427 VanDerWaalsContact OH-CB 3.23Å; Y415-D427 WeakPolarHBondContact OH-CB 3.39Å; S425-D427 PolarHBondContact O-N 3.38Å; D427-A431 VanDerWaalsContact O-CB 3.27Å; D427-A431 WeakPolarHBondContact O-CB 3.26Å; D427-A431 PolarHBondContact O-N 3.01Å
428	S	92.4	Very high	91.4	Very high	4 Å²	4	63.5 Å²	63.5	3%	0.028	33%	0.334	C	S	.	.	H	α-helix	trans	-69.4	-39.1	175.2	-64.7	0	0	0	0	111.9	P422 I423 S425 A431 I432	P422-S428 PolarHBondContact O-OG 3.35Å; P422-S428 VanDerWaalsContact O-OG 3.14Å; I423-S428 WeakPolarHBondContact O-CB 3.49Å; S425-S428 PolarHBondContact O-N 2.85Å; S425-S428 VanDerWaalsContact O-N 3.11Å; S425-S428 WeakPolarHBondContact OG-CB 3.3Å; S425-S428 PolarHBondContact OG-N 3.41Å; S425-S428 VanDerWaalsContact OG-N 3.17Å; S425-S428 PolarHBondContact OG-OG 3.1Å; S428-A431 PolarHBondContact O-N 2.97Å; S428-I432 WeakPolarHBondContact O-CG1 3.44Å; S428-I432 PolarHBondContact O-N 3.16Å
429	I	93.8	Very high	91.5	Very high	98 Å²	98	66.7 Å²	66.7	50%	0.503	35%	0.35	S	S	.	.	H	α-helix	trans	-65.1	-45.7	175.9	-65.8	169.1	0	0	0	110.3	S425 F426 A431 I432 F433	S425-I429 WeakPolarHBondContact O-CG1 3.35Å; S425-I429 PolarHBondContact O-N 3.05Å; F426-I429 PolarHBondContact O-N 3.04Å; I429-A431 VanDerWaalsContact C-N 3.33Å; I429-A431 PolarHBondContact O-N 3.17Å; I429-I432 PolarHBondContact O-N 2.66Å; I429-F433 PolarHBondContact O-N 3.08Å
430	G	94.4	Very high	91.7	Very high	14 Å²	14	70.9 Å²	70.9	14%	0.144	37%	0.371	C	S	.	.	H	α-helix	trans	-63.2	-37.9	176	0	0	0	0	0	112.4	Y87 F426 I432 F433 L434	Y87-G430 VanDerWaalsContact OH-CA 3.28Å; Y87-G430 WeakPolarHBondContact OH-CA 3.44Å; F426-G430 PolarHBondContact O-N 3.12Å; G430-I432 PolarHBondContact O-N 2.93Å; G430-F433 PolarHBondContact O-N 3.4Å; G430-L434 WeakPolarHBondContact O-CB 3.41Å; G430-L434 PolarHBondContact O-N 3.05Å
431	A	95.6	Very high	92.2	Very high	0 Å²	0	65.3 Å²	65.3	0%	0	33%	0.331	C	S	.	.	H	α-helix	trans	-61.4	-41.8	173.2	0	0	0	0	0	112.5	L91 Y415 L416 D427 S428 I429 L434 V435	L91-A431 HydrophobicContact CD1-CB 3.92Å; Y415-A431 HydrophobicContact CD1-CB 3.86Å; Y415-A431 HydrophobicContact CG-CB 4.41Å; L416-A431 HydrophobicContact CD1-CB 4.38Å; L416-A431 HydrophobicContact CD2-CB 4.13Å; L416-A431 HydrophobicContact CG-CB 3.93Å; D427-A431 VanDerWaalsContact O-CB 3.27Å; D427-A431 WeakPolarHBondContact O-CB 3.26Å; D427-A431 PolarHBondContact O-N 3.01Å; S428-A431 PolarHBondContact O-N 2.97Å; I429-A431 VanDerWaalsContact C-N 3.33Å; I429-A431 PolarHBondContact O-N 3.17Å; A431-L434 PolarHBondContact O-N 3.37Å; A431-V435 WeakPolarHBondContact O-CG2 3.16Å; A431-V435 PolarHBondContact O-N 2.73Å
432	I	96.1	Very high	92.6	Very high	73 Å²	73	61 Å²	61	37%	0.374	31%	0.313	S	S	.	.	H	α-helix	trans	-62.3	-48.3	174.4	-67.4	165	0	0	0	110.4	L416 I423 S428 I429 G430 L434 V435 V436	L416-I432 HydrophobicContact CD1-CG1 3.74Å; L416-I432 HydrophobicContact CD2-CD1 4.45Å; L416-I432 HydrophobicContact CD2-CG1 3.97Å; L416-I432 HydrophobicContact CG-CG1 4.5Å; I423-I432 HydrophobicContact CG2-CD1 4.23Å; S428-I432 WeakPolarHBondContact O-CG1 3.44Å; S428-I432 PolarHBondContact O-N 3.16Å; I429-I432 PolarHBondContact O-N 2.66Å; G430-I432 PolarHBondContact O-N 2.93Å; I432-L434 VanDerWaalsContact C-N 3.27Å; I432-L434 PolarHBondContact O-N 3.07Å; I432-V435 PolarHBondContact O-N 3.38Å; I432-V436 HydrophobicContact CG2-CG2 4.35Å; I432-V436 WeakPolarHBondContact O-CG2 3.36Å; I432-V436 PolarHBondContact O-N 2.99Å
433	F	96.3	Very high	93.2	Very high	112 Å²	112	61.5 Å²	61.5	49%	0.491	32%	0.315	S	S	.	.	H	α-helix	trans	-56.3	-44.3	177.8	172.8	-109.7	0	0	0	111.6	L84 I429 G430 V436 F437	L84-F433 HydrophobicContact CD2-CD1 4.26Å; L84-F433 HydrophobicContact CD2-CE1 3.89Å; I429-F433 PolarHBondContact O-N 3.08Å; G430-F433 PolarHBondContact O-N 3.4Å; F433-V436 PolarHBondContact O-N 3.47Å; F433-F437 WeakPolarHBondContact O-CB 3.33Å; F433-F437 PolarHBondContact O-N 2.64Å
434	L	96.4	Very high	93.8	Very high	0 Å²	0	59 Å²	59	0%	0	31%	0.305	C	S	.	.	H	α-helix	trans	-65.7	-39.5	-178.9	-177.4	134.3	0	0	0	111.8	L84 Y87 F408 G430 A431 I432 G438	L84-L434 HydrophobicContact CD2-CD1 4.31Å; Y87-L434 HydrophobicContact CD1-CD1 3.77Å; Y87-L434 HydrophobicContact CE1-CD1 4.38Å; F408-L434 HydrophobicContact CB-CD2 4.47Å; F408-L434 HydrophobicContact CB-CG 4.23Å; F408-L434 WeakPolarHBondContact CB-O 3.34Å; F408-L434 HydrophobicContact CD1-CG 4.39Å; F408-L434 WeakPolarHBondContact O-CD2 3.37Å; G430-L434 WeakPolarHBondContact O-CB 3.41Å; G430-L434 PolarHBondContact O-N 3.05Å; A431-L434 PolarHBondContact O-N 3.37Å; I432-L434 VanDerWaalsContact C-N 3.27Å; I432-L434 PolarHBondContact O-N 3.07Å; L434-G438 PolarHBondContact O-N 2.87Å
435	V	97.6	Very high	94.3	Very high	21 Å²	21	50.3 Å²	50.3	13%	0.127	27%	0.268	C	S	.	.	H	α-helix	trans	-63	-49.7	171.5	173.5	0	0	0	0	111.8	V409 I413 A431 I432 F437 G438 L439	V409-V435 HydrophobicContact CG1-CG1 4.48Å; I413-V435 HydrophobicContact CG1-CG1 4.48Å; I413-V435 HydrophobicContact CG1-CG2 3.91Å; A431-V435 WeakPolarHBondContact O-CG2 3.16Å; A431-V435 PolarHBondContact O-N 2.73Å; I432-V435 PolarHBondContact O-N 3.38Å; V435-F437 PolarHBondContact O-N 3.29Å; V435-G438 PolarHBondContact O-N 3.3Å; V435-L439 HydrophobicContact CG1-CD1 3.97Å; V435-L439 HydrophobicContact CG1-CG 4.48Å; V435-L439 WeakPolarHBondContact O-CG 3.49Å; V435-L439 PolarHBondContact O-N 2.72Å
436	V	96.9	Very high	94.5	Very high	73 Å²	73	51.7 Å²	51.7	44%	0.442	27%	0.274	S	S	.	.	H	α-helix	trans	-62.3	-45.9	-178.2	171.9	0	0	0	0	110.6	I432 F433 G438 L439 I440	I432-V436 HydrophobicContact CG2-CG2 4.35Å; I432-V436 WeakPolarHBondContact O-CG2 3.36Å; I432-V436 PolarHBondContact O-N 2.99Å; F433-V436 PolarHBondContact O-N 3.47Å; V436-G438 PolarHBondContact O-N 2.87Å; V436-L439 PolarHBondContact O-N 3.4Å; V436-I440 HydrophobicContact CG1-CD1 3.66Å; V436-I440 HydrophobicContact CG1-CG1 4.41Å; V436-I440 WeakPolarHBondContact O-CB 3.22Å; V436-I440 VanDerWaalsContact O-CG1 3.32Å; V436-I440 WeakPolarHBondContact O-CG1 3.42Å; V436-I440 PolarHBondContact O-N 3.23Å
437	F	95.6	Very high	94.6	Very high	38 Å²	38	47 Å²	47	17%	0.167	26%	0.259	C	S	.	.	H	α-helix	trans	-58.7	-48	176.3	178.9	-93.7	0	0	0	111.5	L80 L84 F408 F433 V435 L439 I440 M441	L80-F437 HydrophobicContact CD2-CE2 3.92Å; L80-F437 HydrophobicContact CD2-CZ 4Å; L80-F437 HydrophobicContact CG-CZ 4.49Å; L84-F437 HydrophobicContact CD1-CD1 3.58Å; L84-F437 HydrophobicContact CD1-CE1 3.44Å; L84-F437 VanDerWaalsContact CD1-CE1 3.44Å; L84-F437 HydrophobicContact CD1-CE2 4.44Å; L84-F437 HydrophobicContact CD1-CG 4.15Å; L84-F437 HydrophobicContact CD1-CZ 3.91Å; F408-F437 HydrophobicContact CD1-CD1 4.17Å; F408-F437 HydrophobicContact CD1-CE1 4.45Å; F408-F437 HydrophobicContact CD2-CD1 4.4Å; F408-F437 HydrophobicContact CD2-CE1 4.49Å; F408-F437 HydrophobicContact CE1-CD1 4.14Å; F408-F437 AromaticContact CE1-CE1 3.97Å; F408-F437 HydrophobicContact CE1-CE1 3.97Å; F408-F437 HydrophobicContact CE2-CD1 4.45Å; F408-F437 HydrophobicContact CE2-CE1 4.1Å; F408-F437 HydrophobicContact CG-CD1 4.29Å; F408-F437 HydrophobicContact CZ-CD1 4.29Å; F408-F437 AromaticContact CZ-CE1 3.78Å; F408-F437 HydrophobicContact CZ-CE1 3.78Å; F433-F437 WeakPolarHBondContact O-CB 3.33Å; F433-F437 PolarHBondContact O-N 2.64Å; V435-F437 PolarHBondContact O-N 3.29Å; F437-L439 PolarHBondContact O-N 2.96Å; F437-I440 PolarHBondContact O-N 3.5Å; F437-M441 HydrophobicContact CE1-CB 4.43Å; F437-M441 WeakPolarHBondContact O-CB 3.39Å; F437-M441 PolarHBondContact O-N 3.46Å
438	G	95.8	Very high	94.7	Very high	1 Å²	1	47.1 Å²	47.1	1%	0.01	26%	0.261	C	S	.	.	H	α-helix	trans	-60.4	-43.8	178.8	0	0	0	0	0	113.4	S404 L434 V435 V436 G442	S404-G438 WeakPolarHBondContact OG-CA 3.22Å; S404-G438 PolarHBondContact OG-O 3.49Å; L434-G438 PolarHBondContact O-N 2.87Å; V435-G438 PolarHBondContact O-N 3.3Å; V436-G438 PolarHBondContact O-N 2.87Å; G438-G442 PolarHBondContact O-N 3.01Å
439	L	96.3	Very high	94.6	Very high	95 Å²	95	46.9 Å²	46.9	50%	0.497	26%	0.26	S	S	.	.	H	α-helix	trans	-66.2	-47.3	178	-70.7	174.3	0	0	0	111.9	V409 V435 V436 F437 G442 V443	V409-L439 HydrophobicContact CG1-CD2 4.48Å; V409-L439 HydrophobicContact CG2-CD2 4.14Å; V409-L439 HydrophobicContact CG2-CG 4.18Å; V435-L439 HydrophobicContact CG1-CD1 3.97Å; V435-L439 HydrophobicContact CG1-CG 4.48Å; V435-L439 WeakPolarHBondContact O-CG 3.49Å; V435-L439 PolarHBondContact O-N 2.72Å; V436-L439 PolarHBondContact O-N 3.4Å; F437-L439 PolarHBondContact O-N 2.96Å; L439-G442 PolarHBondContact O-N 3.44Å; L439-V443 WeakPolarHBondContact O-CB 3.46Å; L439-V443 VanDerWaalsContact O-CG2 3.29Å; L439-V443 WeakPolarHBondContact O-CG2 3.34Å; L439-V443 PolarHBondContact O-N 2.82Å
440	I	94.9	Very high	94.5	Very high	103 Å²	103	45.9 Å²	45.9	53%	0.528	25%	0.254	S	S	.	.	H	α-helix	trans	-61.9	-50.6	178.1	-68	172.1	0	0	0	109.9	V436 F437 G442 T444	V436-I440 HydrophobicContact CG1-CD1 3.66Å; V436-I440 HydrophobicContact CG1-CG1 4.41Å; V436-I440 WeakPolarHBondContact O-CB 3.22Å; V436-I440 VanDerWaalsContact O-CG1 3.32Å; V436-I440 WeakPolarHBondContact O-CG1 3.42Å; V436-I440 PolarHBondContact O-N 3.23Å; F437-I440 PolarHBondContact O-N 3.5Å; I440-G442 PolarHBondContact O-N 2.72Å; I440-T444 HydrophobicContact CG2-CG2 4.18Å; I440-T444 VanDerWaalsContact O-CB 3.3Å; I440-T444 WeakPolarHBondContact O-CB 3.46Å; I440-T444 VanDerWaalsContact O-CG2 3.22Å; I440-T444 WeakPolarHBondContact O-CG2 3.39Å; I440-T444 PolarHBondContact O-N 3.19Å; I440-T444 PolarHBondContact O-OG1 3.32Å
441	M	93.3	Very high	94.3	Very high	6 Å²	6	49.7 Å²	49.7	3%	0.03	27%	0.271	C	S	.	.	H	α-helix	trans	-59	-47	179.9	-178	-79.2	-79.8	0	0	111.6	I253 P254 A257 S404 F408 F437 T444 S445	I253-M441 HydrophobicContact CB-CG 4.18Å; I253-M441 HydrophobicContact CG2-CE 4.3Å; I253-M441 HydrophobicContact CG2-CG 3.42Å; I253-M441 VanDerWaalsContact CG2-CG 3.42Å; I253-M441 HydrophobicContact CG2-SD 3.97Å; P254-M441 HydrophobicContact CG-SD 4.45Å; A257-M441 HydrophobicContact CB-CE 4.05Å; S404-M441 WeakPolarHBondContact OG-CE 3.4Å; F408-M441 HydrophobicContact CD2-CE 3.83Å; F408-M441 HydrophobicContact CE2-CE 3.36Å; F408-M441 HydrophobicContact CZ-CE 4.44Å; F437-M441 HydrophobicContact CE1-CB 4.43Å; F437-M441 WeakPolarHBondContact O-CB 3.39Å; F437-M441 PolarHBondContact O-N 3.46Å; M441-T444 PolarHBondContact O-OG1 3.12Å; M441-S445 WeakPolarHBondContact O-CB 3.39Å; M441-S445 PolarHBondContact O-N 3.29Å; M441-S445 PolarHBondContact O-OG 2.88Å
442	G	93.9	Very high	93.9	Very high	9 Å²	9	50.9 Å²	50.9	9%	0.093	28%	0.28	C	S	.	.	H	α-helix	trans	-64.1	-49.9	-178.1	0	0	0	0	0	112.4	S400 G438 L439 I440 L446	S400-G442 WeakPolarHBondContact O-CA 3.32Å; G438-G442 PolarHBondContact O-N 3.01Å; L439-G442 PolarHBondContact O-N 3.44Å; I440-G442 PolarHBondContact O-N 2.72Å; G442-L446 WeakPolarHBondContact O-CB 3.28Å; G442-L446 PolarHBondContact O-N 3.28Å
443	V	94.8	Very high	93.5	Very high	93 Å²	93	52 Å²	52	56%	0.564	28%	0.279	S	S	*	.	H	α-helix	trans	-65.8	-47	-178.7	173.9	0	0	0	0	111.2	L439 T447	L439-V443 WeakPolarHBondContact O-CB 3.46Å; L439-V443 VanDerWaalsContact O-CG2 3.29Å; L439-V443 WeakPolarHBondContact O-CG2 3.34Å; L439-V443 PolarHBondContact O-N 2.82Å; V443-T447 VanDerWaalsContact O-CB 3.3Å; V443-T447 WeakPolarHBondContact O-CB 3.41Å; V443-T447 PolarHBondContact O-N 3.48Å; V443-T447 PolarHBondContact O-OG1 3.23Å
444	T	92.9	Very high	93.2	Very high	75 Å²	75	51.2 Å²	51.2	46%	0.46	28%	0.283	S	S	.	.	H	α-helix	trans	-64	-47.7	-179.2	54.3	0	0	0	0	111.5	I440 M441 T447 V448	I440-T444 HydrophobicContact CG2-CG2 4.18Å; I440-T444 VanDerWaalsContact O-CB 3.3Å; I440-T444 WeakPolarHBondContact O-CB 3.46Å; I440-T444 VanDerWaalsContact O-CG2 3.22Å; I440-T444 WeakPolarHBondContact O-CG2 3.39Å; I440-T444 PolarHBondContact O-N 3.19Å; I440-T444 PolarHBondContact O-OG1 3.32Å; M441-T444 PolarHBondContact O-OG1 3.12Å; T444-T447 PolarHBondContact O-N 3.21Å; T444-V448 WeakPolarHBondContact O-CG2 3.49Å; T444-V448 PolarHBondContact O-N 2.95Å
445	S	93	Very high	92.7	Very high	7 Å²	7	58 Å²	58	5%	0.049	32%	0.319	C	S	.	.	H	α-helix	trans	-64.8	-46.5	-179.4	-54.5	0	0	0	0	111.5	P254 M441 T447 V448 I449	P254-S445 VanDerWaalsContact CG-CB 3.43Å; M441-S445 WeakPolarHBondContact O-CB 3.39Å; M441-S445 PolarHBondContact O-N 3.29Å; M441-S445 PolarHBondContact O-OG 2.88Å; S445-T447 VanDerWaalsContact C-N 3.33Å; S445-T447 PolarHBondContact O-N 2.85Å; S445-V448 PolarHBondContact O-N 3.45Å; S445-I449 WeakPolarHBondContact O-CB 3.08Å; S445-I449 WeakPolarHBondContact O-CD1 3.32Å; S445-I449 WeakPolarHBondContact O-CG1 3.14Å; S445-I449 PolarHBondContact O-N 3.32Å
446	L	93.5	Very high	91.8	Very high	50 Å²	50	61.5 Å²	61.5	26%	0.262	34%	0.344	S	S	.	.	H	α-helix	trans	-61.4	-42.6	179.3	-175.7	66.6	0	0	0	111.5	T401 G442 I449 I450	T401-L446 HydrophobicContact CG2-CD1 4.03Å; T401-L446 HydrophobicContact CG2-CD2 3.9Å; T401-L446 HydrophobicContact CG2-CG 4.48Å; G442-L446 WeakPolarHBondContact O-CB 3.28Å; G442-L446 PolarHBondContact O-N 3.28Å; L446-I449 PolarHBondContact O-N 3.06Å; L446-I450 HydrophobicContact CD1-CD1 4.1Å; L446-I450 HydrophobicContact CD1-CG1 4.42Å; L446-I450 HydrophobicContact CD2-CD1 4.48Å; L446-I450 HydrophobicContact CG-CD1 3.86Å; L446-I450 VanDerWaalsContact O-CG1 3.3Å; L446-I450 WeakPolarHBondContact O-CG1 3.26Å; L446-I450 PolarHBondContact O-N 3.2Å
447	T	93.4	Very high	90.4	Very high	70 Å²	70	65.5 Å²	65.5	43%	0.429	38%	0.375	S	S	.	.	H	α-helix	trans	-61.3	-47.2	177.9	-55.9	0	0	0	0	111	V443 T444 S445 I449 I450 L451	V443-T447 VanDerWaalsContact O-CB 3.3Å; V443-T447 WeakPolarHBondContact O-CB 3.41Å; V443-T447 PolarHBondContact O-N 3.48Å; V443-T447 PolarHBondContact O-OG1 3.23Å; T444-T447 PolarHBondContact O-N 3.21Å; S445-T447 VanDerWaalsContact C-N 3.33Å; S445-T447 PolarHBondContact O-N 2.85Å; T447-I449 PolarHBondContact O-N 2.95Å; T447-I450 PolarHBondContact O-N 3.47Å; T447-L451 HydrophobicContact CG2-CD1 4.01Å; T447-L451 HydrophobicContact CG2-CG 4.45Å; T447-L451 WeakPolarHBondContact O-CB 3Å; T447-L451 VanDerWaalsContact O-CG 3.26Å; T447-L451 WeakPolarHBondContact O-CG 3.02Å; T447-L451 PolarHBondContact O-N 2.99Å
448	V	91.6	Very high	90.2	Very high	47 Å²	47	66.9 Å²	66.9	29%	0.285	39%	0.386	S	S	.	.	H	α-helix	trans	-65.9	-38.3	179.3	176.9	0	0	0	0	111.7	I247 A250 T444 S445 L451 S452	I247-V448 HydrophobicContact CG2-CG1 3.9Å; A250-V448 HydrophobicContact CB-CB 3.78Å; A250-V448 HydrophobicContact CB-CG1 3.38Å; A250-V448 HydrophobicContact CB-CG2 4.5Å; T444-V448 WeakPolarHBondContact O-CG2 3.49Å; T444-V448 PolarHBondContact O-N 2.95Å; S445-V448 PolarHBondContact O-N 3.45Å; V448-L451 PolarHBondContact O-N 2.03Å; V448-S452 WeakPolarHBondContact O-CB 3.07Å; V448-S452 PolarHBondContact O-N 3.26Å
449	I	90.6	Very high	89.9	Confident	0 Å²	0	70.3 Å²	70.3	0%	0	41%	0.406	C	S	.	.	H	α-helix	trans	-62.2	-49.5	176.4	-69.5	164.4	0	0	0	110.4	Y251 P254 G396 V397 S445 L446 T447 L451 S452 W453	Y251-I449 HydrophobicContact CD1-CD1 4.23Å; Y251-I449 HydrophobicContact CD1-CG1 4.09Å; Y251-I449 HydrophobicContact CE1-CB 4.41Å; Y251-I449 HydrophobicContact CE1-CD1 4.17Å; Y251-I449 HydrophobicContact CE1-CG1 3.7Å; Y251-I449 HydrophobicContact CE1-CG2 4.02Å; Y251-I449 HydrophobicContact CE2-CG1 4.14Å; Y251-I449 HydrophobicContact CG-CG1 4.48Å; P254-I449 HydrophobicContact CG-CD1 4.49Å; G396-I449 WeakPolarHBondContact O-CD1 3.49Å; V397-I449 HydrophobicContact CG2-CG2 4.45Å; S445-I449 WeakPolarHBondContact O-CB 3.08Å; S445-I449 WeakPolarHBondContact O-CD1 3.32Å; S445-I449 WeakPolarHBondContact O-CG1 3.14Å; S445-I449 PolarHBondContact O-N 3.32Å; L446-I449 PolarHBondContact O-N 3.06Å; T447-I449 PolarHBondContact O-N 2.95Å; I449-L451 PolarHBondContact O-N 3.06Å; I449-S452 WeakPolarHBondContact O-CB 3.14Å; I449-S452 PolarHBondContact O-N 3.2Å; I449-S452 VanDerWaalsContact O-N 3.15Å; I449-S452 PolarHBondContact O-OG 2.91Å; I449-W453 HydrophobicContact CG2-CD2 4.32Å; I449-W453 HydrophobicContact CG2-CH2 4.21Å; I449-W453 HydrophobicContact CG2-CZ2 3.63Å; I449-W453 PolarHBondContact O-N 2.84Å; I449-W453 VanDerWaalsContact O-N 3.12Å
450	I	91.6	Very high	89.5	Confident	76 Å²	76	68.9 Å²	68.9	39%	0.39	40%	0.4	S	S	.	.	H	α-helix	trans	-61.9	-45.8	178.7	-67.7	168.9	0	0	0	110.8	L446 T447 S452 W453 V454	L446-I450 HydrophobicContact CD1-CD1 4.1Å; L446-I450 HydrophobicContact CD1-CG1 4.42Å; L446-I450 HydrophobicContact CD2-CD1 4.48Å; L446-I450 HydrophobicContact CG-CD1 3.86Å; L446-I450 VanDerWaalsContact O-CG1 3.3Å; L446-I450 WeakPolarHBondContact O-CG1 3.26Å; L446-I450 PolarHBondContact O-N 3.2Å; T447-I450 PolarHBondContact O-N 3.47Å; I450-S452 VanDerWaalsContact C-N 3.26Å; I450-S452 PolarHBondContact O-N 3.17Å; I450-W453 HydrophobicContact CG1-CE3 4.5Å; I450-W453 WeakPolarHBondContact O-CB 3.3Å; I450-W453 PolarHBondContact O-N 2.93Å; I450-W453 VanDerWaalsContact O-N 3.12Å; I450-V454 WeakPolarHBondContact O-CG2 3.38Å; I450-V454 PolarHBondContact O-N 3.49Å
451	L	90.4	Very high	89.2	Confident	95 Å²	95	66.9 Å²	66.9	50%	0.497	39%	0.393	S	S	.	.	H	α-helix	trans	-59.5	-39	175.7	-72.8	173.3	0	0	0	111.7	T447 V448 I449 W453 V454 L455	T447-L451 HydrophobicContact CG2-CD1 4.01Å; T447-L451 HydrophobicContact CG2-CG 4.45Å; T447-L451 WeakPolarHBondContact O-CB 3Å; T447-L451 VanDerWaalsContact O-CG 3.26Å; T447-L451 WeakPolarHBondContact O-CG 3.02Å; T447-L451 PolarHBondContact O-N 2.99Å; V448-L451 PolarHBondContact O-N 2.03Å; I449-L451 PolarHBondContact O-N 3.06Å; L451-W453 VanDerWaalsContact C-N 3.27Å; L451-W453 PolarHBondContact O-N 3.18Å; L451-V454 PolarHBondContact O-N 3.17Å; L451-L455 WeakPolarHBondContact O-CB 2.93Å; L451-L455 VanDerWaalsContact O-CG 3.26Å; L451-L455 WeakPolarHBondContact O-CG 3.18Å; L451-L455 PolarHBondContact O-N 3.08Å
452	S	87.3	Confident	88.9	Confident	25 Å²	25	70.8 Å²	70.8	18%	0.175	42%	0.416	C	S	.	.	H	α-helix	trans	-63.5	-34.1	177.6	76.9	0	0	0	0	112.5	Y251 V448 I449 I450 S456	Y251-S452 PolarHBondContact OH-OG 3.36Å; V448-S452 WeakPolarHBondContact O-CB 3.07Å; V448-S452 PolarHBondContact O-N 3.26Å; I449-S452 WeakPolarHBondContact O-CB 3.14Å; I449-S452 PolarHBondContact O-N 3.2Å; I449-S452 VanDerWaalsContact O-N 3.15Å; I449-S452 PolarHBondContact O-OG 2.91Å; I450-S452 VanDerWaalsContact C-N 3.26Å; I450-S452 PolarHBondContact O-N 3.17Å; S452-S456 VanDerWaalsContact O-CB 3.28Å; S452-S456 WeakPolarHBondContact O-CB 2.99Å; S452-S456 PolarHBondContact O-N 3.24Å; S452-S456 PolarHBondContact O-OG 2.84Å; S452-S456 VanDerWaalsContact O-OG 3.08Å
453	W	88.3	Confident	88.6	Confident	95 Å²	95	74.9 Å²	74.9	36%	0.36	44%	0.437	S	S	.	.	H	α-helix	trans	-70.9	-45.5	174.9	-61.9	-21	0	0	0	111.9	N393 V397 I449 I450 L451 L455 S456 S457	N393-W453 HydrophobicContact CB-CZ2 4.03Å; N393-W453 PolarHBondContact OD1-NE1 2.99Å; V397-W453 HydrophobicContact CG2-CH2 3.36Å; V397-W453 HydrophobicContact CG2-CZ2 3.74Å; V397-W453 HydrophobicContact CG2-CZ3 4.44Å; I449-W453 HydrophobicContact CG2-CD2 4.32Å; I449-W453 HydrophobicContact CG2-CH2 4.21Å; I449-W453 HydrophobicContact CG2-CZ2 3.63Å; I449-W453 PolarHBondContact O-N 2.84Å; I449-W453 VanDerWaalsContact O-N 3.12Å; I450-W453 HydrophobicContact CG1-CE3 4.5Å; I450-W453 WeakPolarHBondContact O-CB 3.3Å; I450-W453 PolarHBondContact O-N 2.93Å; I450-W453 VanDerWaalsContact O-N 3.12Å; L451-W453 VanDerWaalsContact C-N 3.27Å; L451-W453 PolarHBondContact O-N 3.18Å; W453-L455 VanDerWaalsContact C-N 3.3Å; W453-L455 PolarHBondContact O-N 3.49Å; W453-S456 WeakPolarHBondContact CA-OG 3.05Å; W453-S456 PolarHBondContact O-N 2.7Å; W453-S456 VanDerWaalsContact O-N 3.1Å; W453-S456 PolarHBondContact O-OG 2.85Å; W453-S457 PolarHBondContact O-N 2.92Å
454	V	89.3	Confident	88.2	Confident	96 Å²	96	73.6 Å²	73.6	58%	0.582	43%	0.428	S	S	*	.	H	α-helix	trans	-61.2	-40	178.8	174.6	0	0	0	0	111.3	I450 L451 S456	I450-V454 WeakPolarHBondContact O-CG2 3.38Å; I450-V454 PolarHBondContact O-N 3.49Å; L451-V454 PolarHBondContact O-N 3.17Å; V454-S456 VanDerWaalsContact C-N 3.29Å; V454-S456 PolarHBondContact O-N 3.24Å
455	L	85.8	Confident	87.8	Confident	142 Å²	142	73.5 Å²	73.5	74%	0.743	43%	0.426	S	S	*	.	H	α-helix	trans	-75.4	-17.1	178	-67.7	170.4	0	0	0	113.6	L451 W453	L451-L455 WeakPolarHBondContact O-CB 2.93Å; L451-L455 VanDerWaalsContact O-CG 3.26Å; L451-L455 WeakPolarHBondContact O-CG 3.18Å; L451-L455 PolarHBondContact O-N 3.08Å; W453-L455 VanDerWaalsContact C-N 3.3Å; W453-L455 PolarHBondContact O-N 3.49Å
456	S	78.8	Confident	87.4	Confident	95 Å²	95	79 Å²	79	66%	0.664	46%	0.457	S	S	*	.	H	α-helix	trans	-97	-11.7	178.7	69.2	0	0	0	0	114.2	S452 W453 V454	S452-S456 VanDerWaalsContact O-CB 3.28Å; S452-S456 WeakPolarHBondContact O-CB 2.99Å; S452-S456 PolarHBondContact O-N 3.24Å; S452-S456 PolarHBondContact O-OG 2.84Å; S452-S456 VanDerWaalsContact O-OG 3.08Å; W453-S456 WeakPolarHBondContact CA-OG 3.05Å; W453-S456 PolarHBondContact O-N 2.7Å; W453-S456 VanDerWaalsContact O-N 3.1Å; W453-S456 PolarHBondContact O-OG 2.85Å; V454-S456 VanDerWaalsContact C-N 3.29Å; V454-S456 PolarHBondContact O-N 3.24Å
457	S	67.8	Low	86.8	Confident	157 Å²	157	81.6 Å²	81.6	100%	1.098	48%	0.475	S	S	*	.			trans	-90.3	0	174	-175.8	0	0	0	0	110.7	W453	W453-S457 PolarHBondContact O-N 2.92Å

Retrieved 457 of 457 residues in 628.3 ms (Link to these results)

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