A0A087XT58_POEFO Loading...

Endothelin-1 receptor

Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

AlphaFold DB , UniProt , Accession A0A087XT58, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 444 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M34.5Very low40.3Very low128 Ų128104.1 Ų104.163%0.63154%0.539SS*.  0-39.80-150.5168.7161.800112.7S3 I4 M5 F389M1-S3 VanDerWaalsContact C-N 3.29Å; M1-S3 PolarHBondContact O-N 2.86Å; M1-I4 PolarHBondContact O-N 3.4Å; M1-M5 HydrophobicContact CE-SD 4.03Å; M1-M5 HydrophobicContact CG-SD 4.24Å; M1-M5 PolarHBondContact O-N 2.98Å; M1-F389 HydrophobicContact CE-CB 3.59Å; M1-F389 HydrophobicContact CE-CD2 3.95Å; M1-F389 HydrophobicContact CE-CG 3.79Å; M1-F389 HydrophobicContact SD-CB 3.84Å; M1-F389 HydrophobicContact SD-CD1 4.44Å; M1-F389 HydrophobicContact SD-CG 4.16Å
2Y28Very low40.7Very low176 Ų176102.8 Ų102.869%0.6953%0.53SS*.Hα-helixtrans-54-36.2172.4-81.6-85.9000115G6Y2-G6 PolarHBondContact O-N 3.35Å
3S34.9Very low41.2Very low90 Ų90104.2 Ų104.263%0.62954%0.538SS*.Hα-helixtrans-70.6-42.4-178.4-163.80000113.2M1 I7M1-S3 VanDerWaalsContact C-N 3.29Å; M1-S3 PolarHBondContact O-N 2.86Å; S3-I7 VanDerWaalsContact O-CD1 3.28Å; S3-I7 WeakPolarHBondContact O-CD1 3.36Å; S3-I7 WeakPolarHBondContact O-CG1 3.45Å; S3-I7 PolarHBondContact O-N 3Å
4I37.1Very low42.1Very low135 Ų135105.4 Ų105.469%0.69254%0.542SS*.Hα-helixtrans-75.6-37.7-177.8-58.6171.8000111.4M1 I7 A8M1-I4 PolarHBondContact O-N 3.4Å; I4-I7 PolarHBondContact O-N 3.47Å; I4-A8 PolarHBondContact O-N 3.08Å; I4-A8 VanDerWaalsContact O-N 3.14Å
5M39.9Very low42.7Very low78 Ų78105.9 Ų105.938%0.38455%0.545SS..Hα-helixtrans-68.7-36.6174.8-93164.358.500112.8M1 I7 A9M1-M5 HydrophobicContact CE-SD 4.03Å; M1-M5 HydrophobicContact CG-SD 4.24Å; M1-M5 PolarHBondContact O-N 2.98Å; M5-I7 VanDerWaalsContact C-N 3.31Å; M5-I7 PolarHBondContact O-N 3.26Å; M5-A9 VanDerWaalsContact O-CB 3.3Å; M5-A9 WeakPolarHBondContact O-CB 3.19Å; M5-A9 PolarHBondContact O-N 3.35Å
6G43.5Very low42.8Very low28 Ų28102.9 Ų102.929%0.28953%0.529SS..Hα-helixtrans-64.2-36.9174.300000112.2Y2 R10Y2-G6 PolarHBondContact O-N 3.35Å; G6-R10 WeakPolarHBondContact O-CB 3.04Å; G6-R10 WeakPolarHBondContact O-CD 3.45Å; G6-R10 WeakPolarHBondContact O-CG 3.41Å; G6-R10 PolarHBondContact O-N 2.88Å
7I43.3Very low43.2Very low87 Ų87100 Ų10045%0.44652%0.524SS..Hα-helixtrans-68.1-50.1177.5-68.1163.3000110.4S3 I4 M5 A9 R10 H11S3-I7 VanDerWaalsContact O-CD1 3.28Å; S3-I7 WeakPolarHBondContact O-CD1 3.36Å; S3-I7 WeakPolarHBondContact O-CG1 3.45Å; S3-I7 PolarHBondContact O-N 3Å; I4-I7 PolarHBondContact O-N 3.47Å; M5-I7 VanDerWaalsContact C-N 3.31Å; M5-I7 PolarHBondContact O-N 3.26Å; I7-A9 PolarHBondContact O-N 3.32Å; I7-R10 PolarHBondContact O-N 2.85Å; I7-H11 WeakPolarHBondContact O-CB 3.45Å; I7-H11 PolarHBondContact O-CD2 2.95Å; I7-H11 VanDerWaalsContact O-CD2 3.23Å; I7-H11 PolarHBondContact O-N 3.43Å
8A42.4Very low43.4Very low58 Ų5898.3 Ų98.348%0.47952%0.521SS..Hα-helixtrans-62.2-42.4179.100000112.6I4 H11 M12I4-A8 PolarHBondContact O-N 3.08Å; I4-A8 VanDerWaalsContact O-N 3.14Å; A8-H11 PolarHBondContact O-N 3.27Å; A8-M12 WeakPolarHBondContact O-CB 3.31Å; A8-M12 WeakPolarHBondContact O-CG 3.47Å; A8-M12 PolarHBondContact O-N 3.13Å
9A41.4Very low43.6Very low43 Ų4396.5 Ų96.536%0.35551%0.512SS..Hα-helixtrans-66.3-39.7175.700000112M5 I7 M12 L13M5-A9 VanDerWaalsContact O-CB 3.3Å; M5-A9 WeakPolarHBondContact O-CB 3.19Å; M5-A9 PolarHBondContact O-N 3.35Å; I7-A9 PolarHBondContact O-N 3.32Å; A9-M12 PolarHBondContact O-N 2.91Å; A9-L13 VanDerWaalsContact O-CB 3.28Å; A9-L13 WeakPolarHBondContact O-CB 3.47Å; A9-L13 PolarHBondContact O-N 2.95Å
10R47.3Very low43.5Very low190 Ų19094.3 Ų94.372%0.71751%0.507SS*.Hα-helixtrans-67-40.7174.1-77.9174.1-175.2-159.11.7112.3G6 I7 L13 M14G6-R10 WeakPolarHBondContact O-CB 3.04Å; G6-R10 WeakPolarHBondContact O-CD 3.45Å; G6-R10 WeakPolarHBondContact O-CG 3.41Å; G6-R10 PolarHBondContact O-N 2.88Å; I7-R10 PolarHBondContact O-N 2.85Å; R10-L13 PolarHBondContact O-N 2.84Å; R10-M14 WeakPolarHBondContact O-CB 3.33Å; R10-M14 WeakPolarHBondContact O-CG 2.99Å; R10-M14 PolarHBondContact O-N 3.44Å
11H50.6Low43.6Very low132 Ų13292.5 Ų92.561%0.61151%0.505SS*.Hα-helixtrans-64.3-42175.5-89.8-85.6000111I7 A8 L15I7-H11 WeakPolarHBondContact O-CB 3.45Å; I7-H11 PolarHBondContact O-CD2 2.95Å; I7-H11 VanDerWaalsContact O-CD2 3.23Å; I7-H11 PolarHBondContact O-N 3.43Å; A8-H11 PolarHBondContact O-N 3.27Å; H11-L15 VanDerWaalsContact O-CB 3.27Å; H11-L15 WeakPolarHBondContact O-CB 3.36Å; H11-L15 PolarHBondContact O-N 3.36Å
12M45.8Very low44.1Very low88 Ų8895.7 Ų95.743%0.43351%0.51SS..Hα-helixtrans-65.9-44.3173.7-76-128.8-80.800112A8 A9 M14 L15 M16 L375A8-M12 WeakPolarHBondContact O-CB 3.31Å; A8-M12 WeakPolarHBondContact O-CG 3.47Å; A8-M12 PolarHBondContact O-N 3.13Å; A9-M12 PolarHBondContact O-N 2.91Å; M12-M14 VanDerWaalsContact C-N 3.33Å; M12-M14 PolarHBondContact O-N 3.32Å; M12-L15 PolarHBondContact O-N 2.83Å; M12-M16 WeakPolarHBondContact O-CB 3.24Å; M12-M16 WeakPolarHBondContact O-CG 3.37Å; M12-M16 PolarHBondContact O-N 3.13Å; M12-L375 HydrophobicContact CE-CD2 4.16Å; M12-L375 HydrophobicContact CE-CG 4.44Å; M12-L375 HydrophobicContact SD-CD1 4.48Å; M12-L375 HydrophobicContact SD-CD2 4.11Å; M12-L375 HydrophobicContact SD-CG 4.47Å
13L47.6Very low44.6Very low121 Ų12188.5 Ų88.563%0.63449%0.49SS*.Hα-helixtrans-63.9-39.4177.5-151.387.8000111.6A9 R10 M16 A17A9-L13 VanDerWaalsContact O-CB 3.28Å; A9-L13 WeakPolarHBondContact O-CB 3.47Å; A9-L13 PolarHBondContact O-N 2.95Å; R10-L13 PolarHBondContact O-N 2.84Å; L13-M16 PolarHBondContact O-N 3.34Å; L13-A17 WeakPolarHBondContact O-CB 3.36Å; L13-A17 PolarHBondContact O-N 2.65Å
14M53Low44.8Very low121 Ų12190.5 Ų90.560%0.59649%0.491SS*.Hα-helixtrans-67.4-41.2174-78-72.4-76.700111.4R10 M12 M16 A17 C18R10-M14 WeakPolarHBondContact O-CB 3.33Å; R10-M14 WeakPolarHBondContact O-CG 2.99Å; R10-M14 PolarHBondContact O-N 3.44Å; M12-M14 VanDerWaalsContact C-N 3.33Å; M12-M14 PolarHBondContact O-N 3.32Å; M14-M16 VanDerWaalsContact C-N 3.34Å; M14-A17 PolarHBondContact O-N 3.1Å; M14-C18 WeakPolarHBondContact O-CB 3.48Å; M14-C18 PolarHBondContact O-N 3.23Å; M14-C18 PolarHBondContact O-SG 3.44Å
15L50.8Low44.7Very low113 Ų11387.7 Ų87.759%0.59248%0.482SS*.Hα-helixtrans-62.8-45.1175.6-15295.6000110.2H11 M12 C18 L19H11-L15 VanDerWaalsContact O-CB 3.27Å; H11-L15 WeakPolarHBondContact O-CB 3.36Å; H11-L15 PolarHBondContact O-N 3.36Å; M12-L15 PolarHBondContact O-N 2.83Å; L15-C18 PolarHBondContact O-N 3.3Å; L15-L19 HydrophobicContact CD2-CD1 4.23Å; L15-L19 HydrophobicContact CG-CD1 4.38Å; L15-L19 WeakPolarHBondContact O-CB 3.3Å; L15-L19 WeakPolarHBondContact O-CD1 3.44Å; L15-L19 WeakPolarHBondContact O-CG 3.36Å; L15-L19 PolarHBondContact O-N 3.21Å
16M45.3Very low44.7Very low58 Ų5889 Ų8929%0.28649%0.488SS..Hα-helixtrans-65.5-40.6177-67.8-64-73.600111.8M12 L13 M14 L19 A20 P339 L368M12-M16 WeakPolarHBondContact O-CB 3.24Å; M12-M16 WeakPolarHBondContact O-CG 3.37Å; M12-M16 PolarHBondContact O-N 3.13Å; L13-M16 PolarHBondContact O-N 3.34Å; M14-M16 VanDerWaalsContact C-N 3.34Å; M16-L19 PolarHBondContact O-N 2.99Å; M16-A20 VanDerWaalsContact O-CB 3.23Å; M16-A20 WeakPolarHBondContact O-CB 3.46Å; M16-A20 PolarHBondContact O-N 2.03Å; M16-P339 HydrophobicContact CE-CB 4.01Å; M16-P339 HydrophobicContact CE-CG 4.12Å; M16-L368 HydrophobicContact CE-CD2 4.44Å
17A50Low44.6Very low54 Ų5492.5 Ų92.545%0.44650%0.499SS..Hα-helixtrans-68.6-39.4175.700000112L13 M14 A20 A21L13-A17 WeakPolarHBondContact O-CB 3.36Å; L13-A17 PolarHBondContact O-N 2.65Å; M14-A17 PolarHBondContact O-N 3.1Å; A17-A20 PolarHBondContact O-N 3.14Å; A17-A21 WeakPolarHBondContact O-CB 3.27Å; A17-A21 PolarHBondContact O-N 3.1Å
18C46.6Very low44.3Very low70 Ų7095.7 Ų95.747%0.47351%0.509SS..Hα-helixtrans-67-39.2174.9-75.80000111.8M14 L15 R22M14-C18 WeakPolarHBondContact O-CB 3.48Å; M14-C18 PolarHBondContact O-N 3.23Å; M14-C18 PolarHBondContact O-SG 3.44Å; L15-C18 PolarHBondContact O-N 3.3Å; C18-R22 WeakPolarHBondContact O-CB 3.32Å; C18-R22 WeakPolarHBondContact O-CG 3.28Å; C18-R22 PolarHBondContact O-N 3.16Å
19L45.9Very low44Very low64 Ų6498 Ų9834%0.33551%0.51SS..Hα-helixtrans-68.8-41.2175.3-71.3168.7000111.3L15 M16 G23L15-L19 HydrophobicContact CD2-CD1 4.23Å; L15-L19 HydrophobicContact CG-CD1 4.38Å; L15-L19 WeakPolarHBondContact O-CB 3.3Å; L15-L19 WeakPolarHBondContact O-CD1 3.44Å; L15-L19 WeakPolarHBondContact O-CG 3.36Å; L15-L19 PolarHBondContact O-N 3.21Å; M16-L19 PolarHBondContact O-N 2.99Å; L19-G23 PolarHBondContact O-N 3.29Å
20A43Very low43.8Very low52 Ų5298.1 Ų98.143%0.4351%0.511SS..Hα-helixtrans-65.9-42174.100000112.2M16 A17 G23 M24M16-A20 VanDerWaalsContact O-CB 3.23Å; M16-A20 WeakPolarHBondContact O-CB 3.46Å; M16-A20 PolarHBondContact O-N 2.03Å; A17-A20 PolarHBondContact O-N 3.14Å; A20-G23 PolarHBondContact O-N 2.91Å; A20-M24 WeakPolarHBondContact O-CG 3.33Å; A20-M24 PolarHBondContact O-N 3.46Å
21A45.8Very low43.4Very low56 Ų5695.4 Ų95.446%0.46351%0.507SS..Hα-helixtrans-66.9-39.2177.600000112.1A17 G23 M24 C25A17-A21 WeakPolarHBondContact O-CB 3.27Å; A17-A21 PolarHBondContact O-N 3.1Å; A21-G23 VanDerWaalsContact C-N 3.33Å; A21-M24 PolarHBondContact O-N 3.27Å; A21-C25 WeakPolarHBondContact O-CB 3.3Å; A21-C25 PolarHBondContact O-N 3.05Å
22R43.9Very low42.9Very low195 Ų19591.7 Ų91.774%0.73650%0.499SS*.Hα-helixtrans-61.6-41.5171.3-81.2-174.1176.3-155.8-0.6111.7C18 C25 Q26C18-R22 WeakPolarHBondContact O-CB 3.32Å; C18-R22 WeakPolarHBondContact O-CG 3.28Å; C18-R22 PolarHBondContact O-N 3.16Å; R22-C25 PolarHBondContact O-N 2.76Å; R22-Q26 VanDerWaalsContact O-CG 3.3Å; R22-Q26 WeakPolarHBondContact O-CG 3.33Å; R22-Q26 PolarHBondContact O-N 2.92Å
23G38.2Very low42.5Very low26 Ų2695.2 Ų95.227%0.26851%0.514SS..Hα-helixtrans-60.9-42.3173.500000112.9L19 A20 A21 I27L19-G23 PolarHBondContact O-N 3.29Å; A20-G23 PolarHBondContact O-N 2.91Å; A21-G23 VanDerWaalsContact C-N 3.33Å; G23-I27 WeakPolarHBondContact O-CD1 3.27Å; G23-I27 VanDerWaalsContact O-CG1 3.3Å; G23-I27 WeakPolarHBondContact O-CG1 3.27Å; G23-I27 PolarHBondContact O-N 3.39Å
24M39.7Very low41.9Very low132 Ų13296.9 Ų96.965%0.6552%0.524SS*.Hα-helixtrans-75.3-28.6178.7-63.7-142.6-56.400114.3A20 A21 I27 K28A20-M24 WeakPolarHBondContact O-CG 3.33Å; A20-M24 PolarHBondContact O-N 3.46Å; A21-M24 PolarHBondContact O-N 3.27Å; M24-I27 PolarHBondContact O-N 3.43Å; M24-K28 PolarHBondContact O-N 3.29Å
25C35.1Very low40.9Very low75 Ų7595.3 Ų95.351%0.50753%0.525SS..Hα-helixtrans-70.5-37.1178-155.10000111.6A21 R22 K28 E29A21-C25 WeakPolarHBondContact O-CB 3.3Å; A21-C25 PolarHBondContact O-N 3.05Å; R22-C25 PolarHBondContact O-N 2.76Å; C25-K28 PolarHBondContact O-N 2.91Å; C25-E29 PolarHBondContact O-N 3.44Å
26Q39.3Very low39.8Very low107 Ų10796.6 Ų96.650%0.553%0.531SS..Hα-helixtrans-68.4-34.4175-66-86.1-77.500112R22 E29 A30R22-Q26 VanDerWaalsContact O-CG 3.3Å; R22-Q26 WeakPolarHBondContact O-CG 3.33Å; R22-Q26 PolarHBondContact O-N 2.92Å; Q26-E29 PolarHBondContact NE2-OE2 2.96Å; Q26-E29 PolarHBondContact O-N 2.98Å; Q26-A30 PolarHBondContact O-N 3.42Å; Q26-A30 VanDerWaalsContact O-N 3.07Å
27I41.9Very low39Very low100 Ų10099 Ų9951%0.51355%0.551SS.*Hα-helixtrans-64.4-41173.3-67.4165.9000111.1G23 M24 A30 E31G23-I27 WeakPolarHBondContact O-CD1 3.27Å; G23-I27 VanDerWaalsContact O-CG1 3.3Å; G23-I27 WeakPolarHBondContact O-CG1 3.27Å; G23-I27 PolarHBondContact O-N 3.39Å; M24-I27 PolarHBondContact O-N 3.43Å; I27-A30 PolarHBondContact O-N 3.11Å; I27-E31 PolarHBondContact O-N 3.02Å
28K36.7Very low38Very low154 Ų154103.1 Ų103.167%0.6757%0.571SS**Hα-helixtrans-69.8-33.9176.5-80.2-171.2173.1-172.30113.5M24 C25 A32M24-K28 PolarHBondContact O-N 3.29Å; C25-K28 PolarHBondContact O-N 2.91Å; K28-A32 WeakPolarHBondContact O-CB 3.44Å; K28-A32 PolarHBondContact O-N 3.21Å
29E36.7Very low37Very low106 Ų106106.7 Ų106.750%0.49558%0.583SS.*Hα-helixtrans-66-39.1172.7-81.3175.514800111.4C25 Q26 A32 Q33C25-E29 PolarHBondContact O-N 3.44Å; Q26-E29 PolarHBondContact NE2-OE2 2.96Å; Q26-E29 PolarHBondContact O-N 2.98Å; E29-A32 PolarHBondContact O-N 3.48Å; E29-Q33 PolarHBondContact O-N 2.71Å; E29-Q33 VanDerWaalsContact O-N 3.13Å
30A36.7Very low36.4Very low46 Ų46112.1 Ų112.138%0.3861%0.607SS.*Hα-helixtrans-66.2-4017500000112.9Q26 I27 Q33 D34Q26-A30 PolarHBondContact O-N 3.42Å; Q26-A30 VanDerWaalsContact O-N 3.07Å; I27-A30 PolarHBondContact O-N 3.11Å; A30-Q33 PolarHBondContact O-N 2.92Å; A30-D34 PolarHBondContact O-N 3.37Å
31E39.5Very low35.6Very low133 Ų133114.4 Ų114.462%0.62162%0.62SS**Hα-helixtrans-69.1-32.5173.2-77.3180152.300112.7I27 Q33 D34I27-E31 PolarHBondContact O-N 3.02Å; E31-Q33 VanDerWaalsContact C-N 3.34Å; E31-D34 PolarHBondContact O-N 2.84Å
32A39.8Very low34.9Very low54 Ų54118.3 Ų118.345%0.44664%0.638SS.*Hα-helixtrans-68.4-33.717700000112.2K28 E29 S35K28-A32 WeakPolarHBondContact O-CB 3.44Å; K28-A32 PolarHBondContact O-N 3.21Å; E29-A32 PolarHBondContact O-N 3.48Å; A32-S35 PolarHBondContact O-N 3.28Å; A32-S35 PolarHBondContact O-OG 2.89Å
33Q37.3Very low34Very low163 Ų163117.1 Ų117.176%0.76265%0.645SS**Hα-helixtrans-73.8-24.8177.8-119.6138.4-1100113.8E29 A30 E31 S35E29-Q33 PolarHBondContact O-N 2.71Å; E29-Q33 VanDerWaalsContact O-N 3.13Å; A30-Q33 PolarHBondContact O-N 2.92Å; E31-Q33 VanDerWaalsContact C-N 3.34Å; Q33-S35 VanDerWaalsContact C-N 3.31Å
34D35.6Very low33.4Very low156 Ų156125 Ų12583%0.83468%0.675SS**THydrogen-bonded Turntrans-84.9-2.6177.5-126.810.6000113.2A30 E31A30-D34 PolarHBondContact O-N 3.37Å; E31-D34 PolarHBondContact O-N 2.84Å
35S31Very low32.6Very low87 Ų87123.6 Ų123.661%0.60868%0.678SS**THydrogen-bonded Turntrans-107.64.8-173.667.50000115.6A32 Q33A32-S35 PolarHBondContact O-N 3.28Å; A32-S35 PolarHBondContact O-OG 2.89Å; Q33-S35 VanDerWaalsContact C-N 3.31Å
36L27.5Very low32.1Very low140 Ų140125.3 Ų125.373%0.73369%0.691SS**SBendtrans-84.1123.8172.4-99.2112.6000111.4V38L36-V38 PolarHBondContact O-N 2.87Å
37P29.6Very low31.4Very low108 Ų108123.7 Ų123.770%0.70170%0.703SS**  trans-71.1129.7177.727.7-30.9000110.7I39P37-I39 PolarHBondContact O-N 3.4Å
38V27.4Very low30.6Very low142 Ų142127.3 Ų127.386%0.86172%0.723SS**  trans-60.8104.6173.9176.50000109.3L36 H40L36-V38 PolarHBondContact O-N 2.87Å; V38-H40 PolarHBondContact O-N 3.36Å
39I26.9Very low29.9Very low144 Ų144128.2 Ų128.274%0.73873%0.729SS**  trans-78.6116168.6-64.9174.4000107.5P37 S41P37-I39 PolarHBondContact O-N 3.4Å; I39-S41 PolarHBondContact O-N 3.38Å
40H32.7Very low29.3Very low179 Ų179129.1 Ų129.183%0.82975%0.747SS**  trans-58.3115.5166-117.2-77.9000109.1V38V38-H40 PolarHBondContact O-N 3.36Å
41S27Very low28.7Very low100 Ų100132.9 Ų132.970%0.69977%0.766SS**  trans-123.6104.2164.447.40000109.9I39 L43I39-S41 PolarHBondContact O-N 3.38Å; S41-L43 PolarHBondContact O-N 2.99Å
42T29.6Very low28.1Very low137 Ų137131.4 Ų131.484%0.8478%0.776SS**  trans-49.9115.9157.22.20000109.2
43L25.2Very low27.4Very low170 Ų170134.2 Ų134.289%0.8979%0.792SS**  trans-143115.1154.7-120.4121.5000110.9S41S41-L43 PolarHBondContact O-N 2.99Å
44Q25.9Very low27.6Very low192 Ų192131.5 Ų131.590%0.89779%0.789SS**  trans-71.7127.9178.5-166.6172.2-300108.8
45S23.2Very low27.1Very low103 Ų103132.3 Ų132.372%0.7279%0.793SS**  trans-157.5110.9155.1-169.10000111.3
46S24.4Very low27Very low110 Ų110135.4 Ų135.477%0.76980%0.802SS**  53.4111.9128.6-30.60000119.1
47G24.8Very low27.4Very low74 Ų74133.9 Ų133.976%0.76380%0.801SS**  trans-65.9167179.400000116.2
48L24.5Very low27.2Very low176 Ų176135 Ų13592%0.92181%0.81SS**  trans-142.3115.3146.5-141.976.6000108
49H23.4Very low27Very low173 Ų173137.1 Ų137.180%0.80181%0.809SS**  trans-61.3143.4168.4-78.2-88.5000110.5
50S24.2Very low27.2Very low125 Ų125137 Ų13787%0.87482%0.815SS**  trans-145.2109.7137.4-82.40000109.4
51T23Very low27.1Very low125 Ų125133.7 Ų133.777%0.76781%0.809SS**  trans-65.8135.8170.436.50000111.9
52A26.5Very low27.1Very low101 Ų101132.8 Ų132.884%0.83582%0.815SS**  trans-149.2109.714200000107.8
53S26.6Very low26.8Very low113 Ų113131.3 Ų131.379%0.7982%0.817SS**  trans-105.2-172.7164.2-57.40000107.6
54P39.8Very low26.7Very low106 Ų106134.5 Ų134.569%0.68882%0.817SS**  -123.1174.2-77.235.9-19.8000110.3
55D25.3Very low26.7Very low173 Ų173133 Ų13393%0.92581%0.812SS**  trans-139.1142.6154.8-94.8-35.6000111.6
56L29.6Very low26.8Very low153 Ų153136.7 Ų136.780%0.80182%0.818SS**  trans-87.7-171.5-153.4-135.375.8000113.1
57P36.5Very low27Very low108 Ų108136 Ų13670%0.70182%0.819SS**  trans-115.1-179.9-14018.111.9000110.3
58S24.7Very low27.1Very low130 Ų130141 Ų14191%0.90983%0.827SS**  trans-149.7125151.637.90000110.9
59F22.5Very low27.3Very low187 Ų187136.3 Ų136.382%0.8282%0.821SS**  trans-120.2134.4-178.8-151.4-84.1000105.4
60V31.2Very low27.4Very low143 Ų143134 Ų13487%0.86782%0.824SS**  trans-159.4146.4147.4159.80000108.5
61P32.2Very low27.6Very low109 Ų109133.3 Ų133.371%0.70882%0.819SS**  trans-116.8169.8-144.238.8-25000114.6
62G25.3Very low28.1Very low80 Ų80132.2 Ų132.283%0.82582%0.817SS**  trans-163.6111.2168.800000112.6
63A24.6Very low28.4Very low107 Ų107131.1 Ų131.188%0.88481%0.808SS**  trans-75.6150.8-176.100000113.9
64R23.4Very low28.7Very low237 Ų237132.6 Ų132.689%0.89481%0.807SS**  160.6118.8113.5-161.6170.2-166.1176.32.1112.7
65M25.2Very low28.5Very low159 Ų159134.3 Ų134.378%0.78381%0.811SS**  trans11.9122.4141.9-110.1157.378.600119.3
66Q25.5Very low29Very low182 Ų182132.5 Ų132.585%0.8581%0.806SS**  178.4139.7102.9-99168.3-000112.1
67A29.1Very low29.6Very low95 Ų95131.1 Ų131.179%0.78580%0.804SS**  trans-69.3140.2178.700000112.1
68L25.3Very low29.8Very low179 Ų179133.9 Ų133.994%0.93781%0.811SS**  trans-155.8112.5154.2-13477.9000110.8
69G30.2Very low30.6Very low77 Ų77136.7 Ų136.779%0.79481%0.807SS**  trans48.495.415300000120.2S71G69-S71 PolarHBondContact O-N 3.44Å
70S25.2Very low31.4Very low125 Ų125138.4 Ų138.487%0.87481%0.808SS**  trans-84.794.6156.167.40000110.4
71S26.9Very low31.9Very low110 Ų110137.4 Ų137.477%0.76981%0.805SS**  trans-45.8135157.1175.80000110.5G69 A73G69-S71 PolarHBondContact O-N 3.44Å; S71-A73 PolarHBondContact O-N 3.42Å; S71-A73 VanDerWaalsContact O-N 3.11Å
72S34.2Very low32.8Very low102 Ų102138.5 Ų138.571%0.71381%0.809SS**  trans-47.4112.8166.1-178.30000110.4
73A32.1Very low34.2Very low79 Ų79139.1 Ų139.165%0.65380%0.801SS**  trans-10699.8168.100000107.8S71 N75S71-A73 PolarHBondContact O-N 3.42Å; S71-A73 VanDerWaalsContact O-N 3.11Å; A73-N75 VanDerWaalsContact C-N 3.3Å; A73-N75 PolarHBondContact O-N 2.87Å
74N33.4Very low35.9Very low144 Ų144137 Ų13777%0.7778%0.778SS**  trans-60.592.4165.8-82.8-22.3000109T76N74-T76 VanDerWaalsContact C-N 3.29Å; N74-T76 PolarHBondContact O-N 2.89Å
75N35.1Very low37.7Very low142 Ų142128.2 Ų128.276%0.75975%0.752SS**  trans-69.790.7167.8-77.1-17.6000108.6A73 V77A73-N75 VanDerWaalsContact C-N 3.3Å; A73-N75 PolarHBondContact O-N 2.87Å; N75-V77 VanDerWaalsContact C-N 3.29Å; N75-V77 PolarHBondContact O-N 3.28Å
76T36.7Very low39.3Very low134 Ų134129.8 Ų129.882%0.82275%0.754SS**  trans-64.496.5158.829.20000107.1N74 L78N74-T76 VanDerWaalsContact C-N 3.29Å; N74-T76 PolarHBondContact O-N 2.89Å; T76-L78 VanDerWaalsContact C-N 3.32Å; T76-L78 PolarHBondContact O-N 3.02Å
77V42.8Very low40.8Very low125 Ų125123.2 Ų123.276%0.75873%0.728SS**  trans-60.498.3170.2176.20000107.3N75 K79N75-V77 VanDerWaalsContact C-N 3.29Å; N75-V77 PolarHBondContact O-N 3.28Å; V77-K79 VanDerWaalsContact C-N 3.28Å; V77-K79 PolarHBondContact O-N 3.03Å
78L40.3Very low42Very low165 Ų165126.2 Ų126.286%0.86474%0.736SS**  trans-6393.8167.6-170.873.9000106.8T76 R80T76-L78 VanDerWaalsContact C-N 3.32Å; T76-L78 PolarHBondContact O-N 3.02Å; L78-R80 VanDerWaalsContact C-N 3.34Å; L78-R80 PolarHBondContact O-N 3.24Å
79K41.7Very low43.3Very low190 Ų190121 Ų12183%0.82672%0.719SS**  trans-56.5100.1171.4-83.1-178.1177.6175.40107.5V77V77-K79 VanDerWaalsContact C-N 3.28Å; V77-K79 PolarHBondContact O-N 3.03Å
80R38.5Very low44.4Very low223 Ų223123.6 Ų123.684%0.84271%0.706SS**  trans-53.3126.3166.5-121.3179.7-164.51785.2106.7L78 V82L78-R80 VanDerWaalsContact C-N 3.34Å; L78-R80 PolarHBondContact O-N 3.24Å; R80-V82 PolarHBondContact O-N 2.9Å
81P43.1Very low45.9Very low122 Ų122119.6 Ų119.679%0.79268%0.677SS**  trans-60.5113.2174.321.7-29000107.9S83P81-S83 PolarHBondContact O-N 3.27Å; P81-S83 VanDerWaalsContact O-N 3.16Å
82V49.9Very low47.3Very low131 Ų131118.8 Ų118.879%0.79467%0.671SS**PPolyproline II helixtrans-59.5118.6174.6177.70000107.2R80R80-V82 PolarHBondContact O-N 2.9Å
83S54.6Low49Very low93 Ų93115.2 Ų115.265%0.6564%0.644SS**PPolyproline II helixtrans-59.3135.2177.551.80000109.5P81P81-S83 PolarHBondContact O-N 3.27Å; P81-S83 VanDerWaalsContact O-N 3.16Å
84P61.4Low51.2Low64 Ų64115 Ų11542%0.41664%0.638SS.*PPolyproline II helixtrans-58.5146.1-179.123.7-32.7000111.2K86 P353P84-K86 PolarHBondContact O-N 3.42Å; P84-P353 WeakPolarHBondContact CB-O 3.34Å
85P61.2Low53.6Low51 Ų51114.2 Ų114.233%0.33163%0.633SS.*PPolyproline II helixtrans-58.8126.7-174.122.4-32.4000110.6C87 R358P85-C87 PolarHBondContact O-N 3.46Å; P85-R358 PolarHBondContact O-NE 2.95Å; P85-R358 PolarHBondContact O-NH2 2.79Å
86K57.8Low55.9Low192 Ų192115.5 Ų115.584%0.83563%0.629SS**PPolyproline II helixtrans-60.1132.4-178.7-66.3-178.1-178.4176.70109.7P84 V88P84-K86 PolarHBondContact O-N 3.42Å; K86-V88 PolarHBondContact O-N 3.48Å
87C57.9Low58.3Low44 Ų44110.7 Ų110.730%0.29760%0.597SS.*PPolyproline II helixtrans-63.5129.3175.1-63.50000109.2P85 A89 C359P85-C87 PolarHBondContact O-N 3.46Å; C87-A89 VanDerWaalsContact C-N 3.31Å; C87-C359 VanDerWaalsContact CA-SG 3.59Å; C87-C359 HydrophobicContact CB-CB 3.94Å; C87-C359 WeakPolarHBondContact CB-SG 3.25Å; C87-C359 WeakPolarHBondContact SG-CB 3.36Å; C87-C359 CovalentContact SG-SG 2.04Å; C87-C359 PolarHBondContact SG-SG 2.69Å
88V54.1Low60.5Low158 Ų158106.6 Ų106.696%0.95857%0.569SS**SBendtrans-72.8-26.7-179.6-178.80000111.5K86K86-V88 PolarHBondContact O-N 3.48Å
89A51.8Low62.8Low71 Ų71106.8 Ų106.859%0.58756%0.559SS**SBendtrans-127.4144174.600000111C87C87-A89 VanDerWaalsContact C-N 3.31Å
90Y53.8Low65.1Low130 Ų130100.9 Ų100.951%0.5154%0.536SS..  trans-58.9135.7170.2-155.1-91.1000108.2S92Y90-S92 PolarHBondContact O-N 3.41Å
91P55.5Low67.5Low41 Ų4190.6 Ų90.627%0.26650%0.497SS..  trans-63.192.2169.724.4-30.2000108.2S363 L366P91-S363 WeakPolarHBondContact CB-OG 3.44Å; P91-L366 HydrophobicContact CB-CD1 4.15Å
92S57.6Low69.7Low93 Ų9386.1 Ų86.165%0.6547%0.468SS*.  trans-99.8114.6-174.7620000109Y90 S94Y90-S92 PolarHBondContact O-N 3.41Å; S92-S94 PolarHBondContact O-N 2.91Å
93I68.9Low71.7Confident28 Ų2882.9 Ų82.914%0.14445%0.448CS..  trans-67.9124.8166.6-61.2174.6000107.3N95 F97 K98 L159I93-N95 PolarHBondContact O-N 3.05Å; I93-F97 HydrophobicContact CG2-CB 4Å; I93-F97 HydrophobicContact CG2-CD1 3.25Å; I93-F97 HydrophobicContact CG2-CE1 4.04Å; I93-F97 HydrophobicContact CG2-CG 3.95Å; I93-K98 HydrophobicContact CB-CG 4.37Å; I93-K98 HydrophobicContact CG2-CG 3.83Å; I93-K98 WeakPolarHBondContact O-CE 3.33Å; I93-L159 HydrophobicContact CD1-CD1 3.63Å; I93-L159 HydrophobicContact CG2-CD1 4.22Å
94S80Confident73.5Confident74 Ų7481.3 Ų81.352%0.51743%0.432SS..  trans-52.7135.8177.5174.20000111S92 Y96 F97 K98S92-S94 PolarHBondContact O-N 2.91Å; S94-Y96 PolarHBondContact O-N 3.4Å; S94-Y96 VanDerWaalsContact O-N 3.15Å; S94-Y96 PolarHBondContact OG-N 3.35Å; S94-F97 WeakPolarHBondContact O-CA 3.5Å; S94-F97 WeakPolarHBondContact O-CB 3.17Å; S94-F97 PolarHBondContact O-N 3.41Å; S94-K98 PolarHBondContact O-N 3.4Å
95N82.4Confident75Confident127 Ų12778.5 Ų78.568%0.67941%0.414SS*.Hα-helixtrans-56.5-32.4178.1-71.7-24.9000112.1I93 K98 Y99I93-N95 PolarHBondContact O-N 3.05Å; N95-K98 PolarHBondContact O-N 3.16Å; N95-Y99 PolarHBondContact O-N 2.89Å
96Y84.9Confident76.5Confident170 Ų17080.1 Ų80.167%0.66742%0.422SS*.Hα-helixtrans-61.9-44.3174-177.1-103.9000112.2S94 Y99 I100S94-Y96 PolarHBondContact O-N 3.4Å; S94-Y96 VanDerWaalsContact O-N 3.15Å; S94-Y96 PolarHBondContact OG-N 3.35Å; Y96-Y99 PolarHBondContact O-N 3.11Å; Y96-I100 HydrophobicContact CD1-CD1 3.73Å; Y96-I100 HydrophobicContact CE1-CD1 3.15Å; Y96-I100 HydrophobicContact CE1-CG1 4.31Å; Y96-I100 HydrophobicContact CE2-CD1 4.06Å; Y96-I100 HydrophobicContact CG-CD1 4.4Å; Y96-I100 WeakPolarHBondContact O-CG1 3.4Å; Y96-I100 PolarHBondContact O-N 3.43Å
97F86.4Confident78.2Confident33 Ų3375.6 Ų75.615%0.14541%0.406CS..Hα-helixtrans-64.1-43.8175.5179.4-86.9000111.3I93 S94 Y99 I100 N101 V367 H370 L371I93-F97 HydrophobicContact CG2-CB 4Å; I93-F97 HydrophobicContact CG2-CD1 3.25Å; I93-F97 HydrophobicContact CG2-CE1 4.04Å; I93-F97 HydrophobicContact CG2-CG 3.95Å; S94-F97 WeakPolarHBondContact O-CA 3.5Å; S94-F97 WeakPolarHBondContact O-CB 3.17Å; S94-F97 PolarHBondContact O-N 3.41Å; F97-Y99 VanDerWaalsContact C-N 3.29Å; F97-Y99 PolarHBondContact O-N 2.98Å; F97-I100 PolarHBondContact O-N 3.15Å; F97-N101 HydrophobicContact CD1-CB 4.38Å; F97-N101 HydrophobicContact CE1-CB 4.13Å; F97-N101 HydrophobicContact CZ-CB 4.5Å; F97-N101 WeakPolarHBondContact O-CB 3.43Å; F97-N101 PolarHBondContact O-N 3.45Å; F97-V367 HydrophobicContact CD2-CG1 4.12Å; F97-V367 HydrophobicContact CE2-CG1 3.64Å; F97-V367 HydrophobicContact CZ-CG1 4.04Å; F97-H370 HydrophobicContact CE1-CB 3.79Å; F97-H370 HydrophobicContact CZ-CB 3.83Å; F97-L371 HydrophobicContact CE2-CD1 4.2Å; F97-L371 HydrophobicContact CE2-CD2 3.79Å; F97-L371 HydrophobicContact CE2-CG 3.75Å; F97-L371 HydrophobicContact CZ-CD2 4.17Å; F97-L371 HydrophobicContact CZ-CG 3.93Å
98K87.8Confident79.9Confident39 Ų3974.1 Ų74.117%0.1740%0.396CS..Hα-helixtrans-55.9-46176.6-64.7-174.7177.6-1760111.3I93 S94 N95 T102 L159I93-K98 HydrophobicContact CB-CG 4.37Å; I93-K98 HydrophobicContact CG2-CG 3.83Å; I93-K98 WeakPolarHBondContact O-CE 3.33Å; S94-K98 PolarHBondContact O-N 3.4Å; N95-K98 PolarHBondContact O-N 3.16Å; K98-T102 VanDerWaalsContact O-CB 3.31Å; K98-T102 WeakPolarHBondContact O-CB 3.4Å; K98-T102 PolarHBondContact O-N 2.9Å; K98-T102 PolarHBondContact O-OG1 3.47Å; K98-L159 HydrophobicContact CB-CG 4.44Å; K98-L159 HydrophobicContact CG-CD1 3.92Å; K98-L159 HydrophobicContact CG-CG 4.18Å
99Y88.8Confident81.8Confident169 Ų16969.2 Ų69.266%0.66336%0.362SS*.Hα-helixtrans-63.4-51.6179.5-170.5-97.8000111.9N95 Y96 F97 N101 T102 V103N95-Y99 PolarHBondContact O-N 2.89Å; Y96-Y99 PolarHBondContact O-N 3.11Å; F97-Y99 VanDerWaalsContact C-N 3.29Å; F97-Y99 PolarHBondContact O-N 2.98Å; Y99-N101 PolarHBondContact O-N 3.35Å; Y99-T102 PolarHBondContact O-N 2.86Å; Y99-V103 HydrophobicContact CD1-CG2 4.18Å; Y99-V103 HydrophobicContact CE1-CG2 3.87Å; Y99-V103 WeakPolarHBondContact O-CG2 3.36Å; Y99-V103 PolarHBondContact O-N 3.49Å
100I89.9Confident83.9Confident66 Ų6669.6 Ų69.634%0.33836%0.357SS..Hα-helixtrans-58-49.3178.1-71.8178000111.3Y96 F97 T102 V103 I104Y96-I100 HydrophobicContact CD1-CD1 3.73Å; Y96-I100 HydrophobicContact CE1-CD1 3.15Å; Y96-I100 HydrophobicContact CE1-CG1 4.31Å; Y96-I100 HydrophobicContact CE2-CD1 4.06Å; Y96-I100 HydrophobicContact CG-CD1 4.4Å; Y96-I100 WeakPolarHBondContact O-CG1 3.4Å; Y96-I100 PolarHBondContact O-N 3.43Å; F97-I100 PolarHBondContact O-N 3.15Å; I100-T102 PolarHBondContact O-N 3.14Å; I100-V103 PolarHBondContact O-N 3.25Å; I100-I104 HydrophobicContact CG2-CD1 3.73Å; I100-I104 HydrophobicContact CG2-CG1 4.43Å; I100-I104 WeakPolarHBondContact O-CG1 3.49Å; I100-I104 PolarHBondContact O-N 2.94Å
101N89.3Confident85.8Confident7 Ų766.5 Ų66.54%0.03735%0.351CS..Hα-helixtrans-60-39.8-178.3-166.396.4000111.1F97 Y99 S105 L159 N374F97-N101 HydrophobicContact CD1-CB 4.38Å; F97-N101 HydrophobicContact CE1-CB 4.13Å; F97-N101 HydrophobicContact CZ-CB 4.5Å; F97-N101 WeakPolarHBondContact O-CB 3.43Å; F97-N101 PolarHBondContact O-N 3.45Å; Y99-N101 PolarHBondContact O-N 3.35Å; N101-S105 WeakPolarHBondContact O-CB 3.47Å; N101-S105 PolarHBondContact O-N 2.91Å; N101-S105 PolarHBondContact O-OG 3.1Å; N101-L159 HydrophobicContact CB-CD2 3.64Å; N101-L159 VanDerWaalsContact ND2-CD2 3.27Å; N101-L159 WeakPolarHBondContact ND2-CD2 3.35Å; N101-N374 PolarHBondContact ND2-ND2 2.88Å; N101-N374 VanDerWaalsContact ND2-ND2 3.19Å; N101-N374 PolarHBondContact OD1-ND2 2.9Å
102T90.4Very high87.7Confident28 Ų2864.5 Ų64.517%0.17234%0.338CS..Hα-helixtrans-67.4-45.8178-57.30000111.4K98 Y99 I100 I104 S105 V106 L160K98-T102 VanDerWaalsContact O-CB 3.31Å; K98-T102 WeakPolarHBondContact O-CB 3.4Å; K98-T102 PolarHBondContact O-N 2.9Å; K98-T102 PolarHBondContact O-OG1 3.47Å; Y99-T102 PolarHBondContact O-N 2.86Å; I100-T102 PolarHBondContact O-N 3.14Å; T102-I104 VanDerWaalsContact C-N 3.34Å; T102-I104 PolarHBondContact O-N 2.86Å; T102-S105 WeakPolarHBondContact O-CB 3.47Å; T102-S105 PolarHBondContact O-N 2.78Å; T102-S105 VanDerWaalsContact O-N 3.17Å; T102-V106 WeakPolarHBondContact O-CG2 3.38Å; T102-V106 PolarHBondContact O-N 3.3Å; T102-L160 HydrophobicContact CG2-CD1 4.1Å
103V92.1Very high89.5Confident62 Ų6263.2 Ų63.238%0.37632%0.324SS..Hα-helixtrans-59.5-45.7176.9171.60000111Y99 I100 S105 V106 I107Y99-V103 HydrophobicContact CD1-CG2 4.18Å; Y99-V103 HydrophobicContact CE1-CG2 3.87Å; Y99-V103 WeakPolarHBondContact O-CG2 3.36Å; Y99-V103 PolarHBondContact O-N 3.49Å; I100-V103 PolarHBondContact O-N 3.25Å; V103-S105 VanDerWaalsContact C-N 3.35Å; V103-S105 PolarHBondContact O-N 3.45Å; V103-V106 PolarHBondContact O-N 3.2Å; V103-I107 HydrophobicContact CG1-CD1 4.02Å; V103-I107 WeakPolarHBondContact O-CG1 3.38Å; V103-I107 PolarHBondContact O-N 3.44Å; V103-I107 VanDerWaalsContact O-N 3.08Å
104I91.8Very high90.7Very high61 Ų6165.4 Ų65.431%0.31334%0.338SS..Hα-helixtrans-59.7-47.5175.3-67.7170.6000110.3I100 T102 V106 I107 V108I100-I104 HydrophobicContact CG2-CD1 3.73Å; I100-I104 HydrophobicContact CG2-CG1 4.43Å; I100-I104 WeakPolarHBondContact O-CG1 3.49Å; I100-I104 PolarHBondContact O-N 2.94Å; T102-I104 VanDerWaalsContact C-N 3.34Å; T102-I104 PolarHBondContact O-N 2.86Å; I104-V106 VanDerWaalsContact C-N 3.3Å; I104-V106 PolarHBondContact O-N 2.88Å; I104-I107 PolarHBondContact O-N 3.41Å; I104-V108 HydrophobicContact CG2-CG2 4.09Å; I104-V108 WeakPolarHBondContact O-CB 3.48Å; I104-V108 WeakPolarHBondContact O-CG2 3.24Å; I104-V108 PolarHBondContact O-N 3.41Å
105S92Very high91.3Very high5 Ų562.6 Ų62.64%0.03532%0.321CS..Hα-helixtrans-57.3-42.3179.4-60.80000112.2N101 T102 V103 V108 F109 N374N101-S105 WeakPolarHBondContact O-CB 3.47Å; N101-S105 PolarHBondContact O-N 2.91Å; N101-S105 PolarHBondContact O-OG 3.1Å; T102-S105 WeakPolarHBondContact O-CB 3.47Å; T102-S105 PolarHBondContact O-N 2.78Å; T102-S105 VanDerWaalsContact O-N 3.17Å; V103-S105 VanDerWaalsContact C-N 3.35Å; V103-S105 PolarHBondContact O-N 3.45Å; S105-V108 PolarHBondContact O-N 3Å; S105-F109 VanDerWaalsContact O-CB 3.29Å; S105-F109 WeakPolarHBondContact O-CB 3.42Å; S105-F109 PolarHBondContact O-N 3.45Å; S105-N374 PolarHBondContact OG-OD1 3.29Å
106V93.3Very high91.9Very high84 Ų8456.6 Ų56.651%0.50929%0.289SS..Hα-helixtrans-65.6-44.8178171.60000111.5T102 V103 I104 V108 F109 V110T102-V106 WeakPolarHBondContact O-CG2 3.38Å; T102-V106 PolarHBondContact O-N 3.3Å; V103-V106 PolarHBondContact O-N 3.2Å; I104-V106 VanDerWaalsContact C-N 3.3Å; I104-V106 PolarHBondContact O-N 2.88Å; V106-V108 VanDerWaalsContact C-N 3.35Å; V106-V108 PolarHBondContact O-N 2.91Å; V106-F109 PolarHBondContact O-N 2.89Å; V106-V110 WeakPolarHBondContact O-CG2 3.45Å; V106-V110 PolarHBondContact O-N 2.97Å
107I93.5Very high92.4Very high98 Ų9850.6 Ų50.650%0.50328%0.275SS..Hα-helixtrans-61-47.6177.3-67.4167.1000110.1V103 I104 F109 V110 V111V103-I107 HydrophobicContact CG1-CD1 4.02Å; V103-I107 WeakPolarHBondContact O-CG1 3.38Å; V103-I107 PolarHBondContact O-N 3.44Å; V103-I107 VanDerWaalsContact O-N 3.08Å; I104-I107 PolarHBondContact O-N 3.41Å; I107-F109 VanDerWaalsContact C-N 3.33Å; I107-F109 PolarHBondContact O-N 3.32Å; I107-V110 PolarHBondContact O-N 2.97Å; I107-V111 HydrophobicContact CG2-CG2 4.25Å; I107-V111 WeakPolarHBondContact O-CB 3.06Å; I107-V111 VanDerWaalsContact O-CG2 3.28Å; I107-V111 WeakPolarHBondContact O-CG2 3.18Å; I107-V111 PolarHBondContact O-N 3.26Å
108V93.6Very high92.7Very high12 Ų1249.8 Ų49.87%0.07327%0.272CS..Hα-helixtrans-61.4-42.6179172.90000110.6I104 S105 V106 G112 I152 I378 C381I104-V108 HydrophobicContact CG2-CG2 4.09Å; I104-V108 WeakPolarHBondContact O-CB 3.48Å; I104-V108 WeakPolarHBondContact O-CG2 3.24Å; I104-V108 PolarHBondContact O-N 3.41Å; S105-V108 PolarHBondContact O-N 3Å; V106-V108 VanDerWaalsContact C-N 3.35Å; V106-V108 PolarHBondContact O-N 2.91Å; V108-G112 WeakPolarHBondContact O-CA 3.37Å; V108-G112 PolarHBondContact O-N 3.44Å; V108-I152 HydrophobicContact CB-CD1 4.34Å; V108-I152 HydrophobicContact CG1-CD1 3.86Å; V108-I378 HydrophobicContact CG1-CG1 4.34Å; V108-I378 HydrophobicContact CG2-CD1 4.3Å; V108-I378 HydrophobicContact CG2-CG1 3.53Å; V108-C381 WeakPolarHBondContact CG1-SG 3.39Å; V108-C381 PolarHBondContact O-SG 3.12Å
109F94.9Very high92.9Very high55 Ų5548 Ų4824%0.24127%0.265CS..Hα-helixtrans-58.5-51.2176.3-176.1-99.2000112.3S105 V106 I107 L113 I148 I152 P153S105-F109 VanDerWaalsContact O-CB 3.29Å; S105-F109 WeakPolarHBondContact O-CB 3.42Å; S105-F109 PolarHBondContact O-N 3.45Å; V106-F109 PolarHBondContact O-N 2.89Å; I107-F109 VanDerWaalsContact C-N 3.33Å; I107-F109 PolarHBondContact O-N 3.32Å; F109-L113 HydrophobicContact CE1-CD2 4.25Å; F109-L113 HydrophobicContact CZ-CD2 4.44Å; F109-L113 WeakPolarHBondContact O-CB 3.25Å; F109-L113 PolarHBondContact O-N 2.96Å; F109-I148 HydrophobicContact CD2-CG2 3.81Å; F109-I148 HydrophobicContact CE2-CG2 4.37Å; F109-I152 HydrophobicContact CB-CD1 3.89Å; F109-I152 HydrophobicContact CB-CG2 4.12Å; F109-I152 HydrophobicContact CD2-CB 4.08Å; F109-I152 HydrophobicContact CD2-CD1 4.24Å; F109-I152 HydrophobicContact CD2-CG2 4.21Å; F109-P153 HydrophobicContact CE2-CG 4.18Å
110V94.8Very high93.2Very high80 Ų8042.1 Ų42.149%0.48524%0.244SC..Hα-helixtrans-64.7-50.2-178.7174.30000111V106 I107 G112 L113 V114V106-V110 WeakPolarHBondContact O-CG2 3.45Å; V106-V110 PolarHBondContact O-N 2.97Å; I107-V110 PolarHBondContact O-N 2.97Å; V110-G112 VanDerWaalsContact C-N 3.35Å; V110-G112 PolarHBondContact O-N 3.34Å; V110-L113 PolarHBondContact O-N 2.91Å; V110-V114 HydrophobicContact CG1-CG2 4.44Å; V110-V114 WeakPolarHBondContact O-CB 3.24Å; V110-V114 VanDerWaalsContact O-CG2 3.27Å; V110-V114 WeakPolarHBondContact O-CG2 3.49Å; V110-V114 PolarHBondContact O-N 2.64Å
111V94.2Very high93.3Very high64 Ų6445.4 Ų45.439%0.38825%0.253SS..Hα-helixtrans-63-44-178.7172.60000110.9I107 G115 I385I107-V111 HydrophobicContact CG2-CG2 4.25Å; I107-V111 WeakPolarHBondContact O-CB 3.06Å; I107-V111 VanDerWaalsContact O-CG2 3.28Å; I107-V111 WeakPolarHBondContact O-CG2 3.18Å; I107-V111 PolarHBondContact O-N 3.26Å; V111-G115 WeakPolarHBondContact O-CA 3.2Å; V111-G115 PolarHBondContact O-N 3.37Å; V111-I385 HydrophobicContact CG1-CD1 4.3Å
112G94.5Very high93.3Very high0 Ų045.2 Ų45.20%025%0.252CS..Hα-helixtrans-65.6-44.8-179.800000113V108 V110 N116 C381V108-G112 WeakPolarHBondContact O-CA 3.37Å; V108-G112 PolarHBondContact O-N 3.44Å; V110-G112 VanDerWaalsContact C-N 3.35Å; V110-G112 PolarHBondContact O-N 3.34Å; G112-N116 WeakPolarHBondContact O-CB 3.25Å; G112-N116 PolarHBondContact O-N 2.91Å; G112-N116 PolarHBondContact O-ND2 3.44Å; G112-C381 WeakPolarHBondContact CA-SG 3.49Å
113L95Very high93.3Very high66 Ų6644.5 Ų44.535%0.34625%0.247SC..Hα-helixtrans-63.8-52.7177.6-17564.8000110.9F109 V110 A117 L145F109-L113 HydrophobicContact CE1-CD2 4.25Å; F109-L113 HydrophobicContact CZ-CD2 4.44Å; F109-L113 WeakPolarHBondContact O-CB 3.25Å; F109-L113 PolarHBondContact O-N 2.96Å; V110-L113 PolarHBondContact O-N 2.91Å; L113-A117 WeakPolarHBondContact O-CB 3.46Å; L113-A117 PolarHBondContact O-N 3.43Å; L113-L145 HydrophobicContact CD1-CD2 3.73Å
114V94.4Very high93.1Very high74 Ų7449.7 Ų49.745%0.44826%0.26SS..Hα-helixtrans-63.8-45.8-179.1173.90000110.9V110 T118 L402V110-V114 HydrophobicContact CG1-CG2 4.44Å; V110-V114 WeakPolarHBondContact O-CB 3.24Å; V110-V114 VanDerWaalsContact O-CG2 3.27Å; V110-V114 WeakPolarHBondContact O-CG2 3.49Å; V110-V114 PolarHBondContact O-N 2.64Å; V114-T118 WeakPolarHBondContact O-CB 3.33Å; V114-T118 PolarHBondContact O-N 2.83Å; V114-T118 PolarHBondContact O-OG1 3.33Å; V114-L402 HydrophobicContact CG1-CD2 4.36Å
115G93.8Very high92.9Very high15 Ų1551.7 Ų51.716%0.15527%0.269CS..Hα-helixtrans-62.9-52.5-177.700000112.6V111 T118 L119V111-G115 WeakPolarHBondContact O-CA 3.2Å; V111-G115 PolarHBondContact O-N 3.37Å; G115-T118 PolarHBondContact O-N 3.43Å; G115-L119 WeakPolarHBondContact O-CB 3.44Å; G115-L119 PolarHBondContact O-N 2.97Å
116N95.4Very high92.5Very high0 Ų054.3 Ų54.30%028%0.282CS..Hα-helixtrans-71.5-37.2-178-71.7-62.9000112.3G112 L119 L120 A141 L145 S380 P384G112-N116 WeakPolarHBondContact O-CB 3.25Å; G112-N116 PolarHBondContact O-N 2.91Å; G112-N116 PolarHBondContact O-ND2 3.44Å; N116-L119 PolarHBondContact O-N 3.17Å; N116-L120 PolarHBondContact O-N 3.39Å; N116-A141 HydrophobicContact CB-CB 4.33Å; N116-L145 HydrophobicContact CB-CD1 4.35Å; N116-L145 HydrophobicContact CB-CD2 3.78Å; N116-L145 HydrophobicContact CB-CG 3.69Å; N116-S380 PolarHBondContact ND2-O 3.3Å; N116-P384 HydrophobicContact CB-CG 4.47Å; N116-P384 WeakPolarHBondContact OD1-CD 3.41Å; N116-P384 VanDerWaalsContact OD1-CG 3.26Å; N116-P384 WeakPolarHBondContact OD1-CG 3.24Å
117A94.9Very high91.9Very high45 Ų4556.7 Ų56.737%0.37229%0.286SS..Hα-helixtrans-64.1-41.6173.600000111.9L113 L119 L120 R121L113-A117 WeakPolarHBondContact O-CB 3.46Å; L113-A117 PolarHBondContact O-N 3.43Å; A117-L119 VanDerWaalsContact C-N 3.34Å; A117-L120 PolarHBondContact O-N 3.42Å; A117-R121 WeakPolarHBondContact O-CB 3.36Å; A117-R121 PolarHBondContact O-N 3Å
118T92.6Very high91.2Very high15 Ų1554.3 Ų54.39%0.09228%0.277CS..Hα-helixtrans-64-40.9175.6-59.40000111.2V114 G115 R121 I122 F398 C401 L402V114-T118 WeakPolarHBondContact O-CB 3.33Å; V114-T118 PolarHBondContact O-N 2.83Å; V114-T118 PolarHBondContact O-OG1 3.33Å; G115-T118 PolarHBondContact O-N 3.43Å; T118-R121 PolarHBondContact O-N 3.3Å; T118-I122 HydrophobicContact CG2-CD1 3.89Å; T118-I122 HydrophobicContact CG2-CG1 4.37Å; T118-I122 VanDerWaalsContact O-CG1 3.28Å; T118-I122 WeakPolarHBondContact O-CG1 3.33Å; T118-I122 PolarHBondContact O-N 3.38Å; T118-F398 HydrophobicContact CG2-CD1 3.67Å; T118-F398 HydrophobicContact CG2-CE1 3.74Å; T118-C401 HydrophobicContact CG2-CB 4.12Å; T118-L402 HydrophobicContact CG2-CD2 4.22Å; T118-L402 HydrophobicContact CG2-CG 4.22Å
119L92.7Very high90.5Very high2 Ų253.9 Ų53.91%0.0127%0.274CS..Hα-helixtrans-60.3-46.9176.4-179.357.1000111.8G115 N116 A117 I122 I123 I137 A141 P384 L387 F394 F398G115-L119 WeakPolarHBondContact O-CB 3.44Å; G115-L119 PolarHBondContact O-N 2.97Å; N116-L119 PolarHBondContact O-N 3.17Å; A117-L119 VanDerWaalsContact C-N 3.34Å; L119-I122 PolarHBondContact O-N 3.19Å; L119-I123 HydrophobicContact CD1-CD1 4.02Å; L119-I123 HydrophobicContact CG-CD1 4.19Å; L119-I123 WeakPolarHBondContact O-CG1 3.48Å; L119-I123 PolarHBondContact O-N 3Å; L119-I123 VanDerWaalsContact O-N 3.15Å; L119-I137 HydrophobicContact CD1-CG2 4.19Å; L119-I137 HydrophobicContact CD2-CG2 3.8Å; L119-I137 HydrophobicContact CG-CG2 4.23Å; L119-A141 HydrophobicContact CD2-CB 4Å; L119-A141 HydrophobicContact CG-CB 4.42Å; L119-P384 HydrophobicContact CD2-CG 4.25Å; L119-L387 HydrophobicContact CD1-CD1 4.01Å; L119-L387 HydrophobicContact CD2-CD1 3.69Å; L119-F394 HydrophobicContact CD1-CD1 3.87Å; L119-F394 HydrophobicContact CD1-CE1 3.6Å; L119-F394 HydrophobicContact CD1-CZ 4.46Å; L119-F398 HydrophobicContact CB-CZ 4.03Å; L119-F398 HydrophobicContact CD1-CE2 4.29Å; L119-F398 HydrophobicContact CD1-CZ 4Å
120L93.7Very high90Very high46 Ų4655.8 Ų55.824%0.24128%0.28CS..Hα-helixtrans-59.6-46.1174-74.8177.7000111.6N116 A117 I122 I123 Y124 A138 A141 L142 L145N116-L120 PolarHBondContact O-N 3.39Å; A117-L120 PolarHBondContact O-N 3.42Å; L120-I122 PolarHBondContact O-N 3.38Å; L120-I123 PolarHBondContact O-N 3.49Å; L120-Y124 WeakPolarHBondContact O-CB 3.14Å; L120-Y124 PolarHBondContact O-N 3.43Å; L120-A138 HydrophobicContact CD2-CB 3.83Å; L120-A138 WeakPolarHBondContact CD2-O 3.49Å; L120-A141 HydrophobicContact CD2-CB 4.05Å; L120-A141 HydrophobicContact CG-CB 3.98Å; L120-L142 HydrophobicContact CD1-CD1 4.47Å; L120-L145 HydrophobicContact CD1-CD1 3.53Å
121R91.9Very high89.5Confident135 Ų13553.8 Ų53.851%0.50927%0.266SS..Hα-helixtrans-58.6-44.9177.5-179.4178173.2175.61111.9A117 T118 I123 Y124 Q125A117-R121 WeakPolarHBondContact O-CB 3.36Å; A117-R121 PolarHBondContact O-N 3Å; T118-R121 PolarHBondContact O-N 3.3Å; R121-I123 PolarHBondContact O-N 2.98Å; R121-Y124 PolarHBondContact O-N 2.98Å; R121-Q125 HydrophobicContact CG-CG 4.23Å; R121-Q125 WeakPolarHBondContact O-CB 3.09Å; R121-Q125 WeakPolarHBondContact O-CG 3.26Å; R121-Q125 PolarHBondContact O-N 3.47Å
122I89.4Confident89Confident3 Ų351 Ų512%0.01525%0.25CS..Hα-helixtrans-59.8-45.9178.7-74.4165.7000111.2T118 L119 L120 N126 F394 C397 F398 C401T118-I122 HydrophobicContact CG2-CD1 3.89Å; T118-I122 HydrophobicContact CG2-CG1 4.37Å; T118-I122 VanDerWaalsContact O-CG1 3.28Å; T118-I122 WeakPolarHBondContact O-CG1 3.33Å; T118-I122 PolarHBondContact O-N 3.38Å; L119-I122 PolarHBondContact O-N 3.19Å; L120-I122 PolarHBondContact O-N 3.38Å; I122-N126 WeakPolarHBondContact O-CB 3.39Å; I122-N126 PolarHBondContact O-N 3.44Å; I122-N126 VanDerWaalsContact O-N 3.14Å; I122-N126 PolarHBondContact O-ND2 3.37Å; I122-F394 HydrophobicContact CG2-CD1 4.43Å; I122-C397 HydrophobicContact CB-CB 4.37Å; I122-C397 HydrophobicContact CD1-CB 3.9Å; I122-C397 HydrophobicContact CG1-CB 3.99Å; I122-C397 HydrophobicContact CG2-CB 3.46Å; I122-C397 VanDerWaalsContact CG2-CB 3.46Å; I122-F398 HydrophobicContact CD1-CB 4.33Å; I122-F398 HydrophobicContact CD1-CD1 3.64Å; I122-F398 HydrophobicContact CD1-CD2 4.05Å; I122-F398 HydrophobicContact CD1-CE1 3.87Å; I122-F398 HydrophobicContact CD1-CE2 4.25Å; I122-F398 HydrophobicContact CD1-CG 3.72Å; I122-F398 HydrophobicContact CD1-CZ 4.17Å; I122-C401 HydrophobicContact CG1-CB 4.41Å
123I90.1Very high88.5Confident13 Ų1351.4 Ų51.47%0.06725%0.253CS..Hα-helixtrans-70.2-39-178.5-64165.2000110.3L119 L120 R121 R130 I137 A138 F394L119-I123 HydrophobicContact CD1-CD1 4.02Å; L119-I123 HydrophobicContact CG-CD1 4.19Å; L119-I123 WeakPolarHBondContact O-CG1 3.48Å; L119-I123 PolarHBondContact O-N 3Å; L119-I123 VanDerWaalsContact O-N 3.15Å; L120-I123 PolarHBondContact O-N 3.49Å; R121-I123 PolarHBondContact O-N 2.98Å; I123-R130 WeakPolarHBondContact O-CG 3.37Å; I123-I137 HydrophobicContact CD1-CG2 4.1Å; I123-A138 HydrophobicContact CD1-CB 4Å; I123-A138 HydrophobicContact CG2-CB 4.36Å; I123-F394 HydrophobicContact CD1-CE1 4.31Å; I123-F394 HydrophobicContact CG1-CE1 4.11Å
124Y88.7Confident88.2Confident170 Ų17048.9 Ų48.967%0.66724%0.24SC*.Hα-helixtrans-64.8-49.2176.4-177.2-105000111.6L120 R121 R130L120-Y124 WeakPolarHBondContact O-CB 3.14Å; L120-Y124 PolarHBondContact O-N 3.43Å; R121-Y124 PolarHBondContact O-N 2.98Å; Y124-R130 VanDerWaalsContact O-CZ 3.26Å; Y124-R130 PolarHBondContact O-NE 2.97Å; Y124-R130 VanDerWaalsContact O-NE 3.1Å; Y124-R130 PolarHBondContact O-NH2 3.15Å
125Q87.3Confident88Confident104 Ų10446 Ų4649%0.48622%0.223SC..Hα-helixtrans-73.8-35.6-173.6-69.3-177.4-26.900113.3R121 K127R121-Q125 HydrophobicContact CG-CG 4.23Å; R121-Q125 WeakPolarHBondContact O-CB 3.09Å; R121-Q125 WeakPolarHBondContact O-CG 3.26Å; R121-Q125 PolarHBondContact O-N 3.47Å; Q125-K127 PolarHBondContact O-N 3.34Å
126N82.8Confident87.9Confident59 Ų5945.3 Ų45.332%0.31622%0.216SC..  trans-92.7104.4-174.8-65-64000111.8I122 C128 M129I122-N126 WeakPolarHBondContact O-CB 3.39Å; I122-N126 PolarHBondContact O-N 3.44Å; I122-N126 VanDerWaalsContact O-N 3.14Å; I122-N126 PolarHBondContact O-ND2 3.37Å; N126-C128 PolarHBondContact O-N 2.82Å; N126-C128 VanDerWaalsContact O-N 3.14Å; N126-M129 HydrophobicContact CB-CB 3.99Å; N126-M129 HydrophobicContact CB-CG 3.7Å; N126-M129 WeakPolarHBondContact O-CA 3.1Å; N126-M129 WeakPolarHBondContact O-CB 3.47Å; N126-M129 PolarHBondContact O-N 2.93Å
127K81.4Confident87.7Confident135 Ų13545.9 Ų45.959%0.58722%0.219SC*.G310 helixtrans-52.8-37.9176-68.6-177.1-178.8177.70112.5Q125 M129 R130Q125-K127 PolarHBondContact O-N 3.34Å; K127-M129 PolarHBondContact O-N 2.84Å; K127-M129 VanDerWaalsContact O-N 3.16Å; K127-R130 WeakPolarHBondContact O-CB 3.26Å; K127-R130 PolarHBondContact O-N 3.5Å
128C78.8Confident87.6Confident47 Ų4744.6 Ų44.632%0.31821%0.209SC..G310 helixtrans-70.4-6.7178.2-54.20000114.4N126 K393 C425N126-C128 PolarHBondContact O-N 2.82Å; N126-C128 VanDerWaalsContact O-N 3.14Å; C128-K393 PolarHBondContact O-NZ 2.82Å; C128-C425 HydrophobicContact CB-CB 4.12Å; C128-C425 WeakPolarHBondContact CB-SG 3.32Å; C128-C425 WeakPolarHBondContact SG-CB 3.18Å; C128-C425 CovalentContact SG-SG 2.03Å; C128-C425 PolarHBondContact SG-SG 3.44Å
129M80Confident87.7Confident3 Ų344.2 Ų44.22%0.01521%0.207CC..G310 helixtrans-100.2-4.9172.6-65.3-65.7-81.800112.4N126 K127 N131 N134 K393 F394N126-M129 HydrophobicContact CB-CB 3.99Å; N126-M129 HydrophobicContact CB-CG 3.7Å; N126-M129 WeakPolarHBondContact O-CA 3.1Å; N126-M129 WeakPolarHBondContact O-CB 3.47Å; N126-M129 PolarHBondContact O-N 2.93Å; K127-M129 PolarHBondContact O-N 2.84Å; K127-M129 VanDerWaalsContact O-N 3.16Å; M129-N131 PolarHBondContact O-N 2.94Å; M129-N131 VanDerWaalsContact O-N 3.1Å; M129-N134 WeakPolarHBondContact O-CB 3.39Å; M129-N134 PolarHBondContact O-ND2 3.37Å; M129-K393 HydrophobicContact CE-CD 4.45Å; M129-K393 HydrophobicContact CE-CG 4.39Å; M129-K393 HydrophobicContact SD-CD 3.38Å; M129-K393 WeakPolarHBondContact SD-CD 3.26Å; M129-K393 WeakPolarHBondContact SD-CE 3.33Å; M129-K393 HydrophobicContact SD-CG 3.71Å; M129-K393 PolarHBondContact SD-NZ 2.87Å; M129-F394 HydrophobicContact CE-CD1 3.45Å; M129-F394 VanDerWaalsContact CE-CD1 3.45Å; M129-F394 HydrophobicContact CE-CD2 4.02Å; M129-F394 HydrophobicContact CE-CE1 3.17Å; M129-F394 HydrophobicContact CE-CE2 3.77Å; M129-F394 HydrophobicContact CE-CG 3.87Å; M129-F394 HydrophobicContact CE-CZ 3.34Å
130R84.6Confident87.7Confident96 Ų9644.6 Ų44.636%0.36221%0.209SC..  trans-86.680.2-179.1-61-179.3-175.6-179.5-3.6111I123 Y124 K127 G215I123-R130 WeakPolarHBondContact O-CG 3.37Å; Y124-R130 VanDerWaalsContact O-CZ 3.26Å; Y124-R130 PolarHBondContact O-NE 2.97Å; Y124-R130 VanDerWaalsContact O-NE 3.1Å; Y124-R130 PolarHBondContact O-NH2 3.15Å; K127-R130 WeakPolarHBondContact O-CB 3.26Å; K127-R130 PolarHBondContact O-N 3.5Å; R130-G215 CarbonylContact O-C 3.52Å; R130-G215 PolarHBondContact O-N 3.08Å
131N84.5Confident87.8Confident38 Ų3842.4 Ų42.420%0.20320%0.198CC..BIsolated β-bridgetrans-129.6168.2174.361.641.9000110.3M129 P133 N134 A135M129-N131 PolarHBondContact O-N 2.94Å; M129-N131 VanDerWaalsContact O-N 3.1Å; N131-P133 WeakPolarHBondContact OD1-CD 3.48Å; N131-N134 PolarHBondContact ND2-ND2 2.87Å; N131-N134 PolarHBondContact O-N 3.34Å; N131-N134 VanDerWaalsContact OD1-CB 3.24Å; N131-N134 WeakPolarHBondContact OD1-CB 3.34Å; N131-N134 PolarHBondContact OD1-N 3.43Å; N131-N134 PolarHBondContact OD1-ND2 2.86Å; N131-A135 PolarHBondContact O-N 2.82Å
132G83.6Confident88Confident5 Ų539.6 Ų39.65%0.05219%0.192CC..Hα-helixtrans-50.7-54.8-177.200000114.5N134 A135 L136G132-N134 VanDerWaalsContact C-N 3.3Å; G132-N134 PolarHBondContact O-N 2.92Å; G132-A135 WeakPolarHBondContact O-CB 3.28Å; G132-A135 PolarHBondContact O-N 3.09Å; G132-L136 PolarHBondContact O-N 3.36Å; G132-L136 VanDerWaalsContact O-N 3.11Å
133P82.9Confident88.2Confident9 Ų939.5 Ų39.56%0.05819%0.192CC..Hα-helixtrans-62.7-34.5-178.8-20.929.8000113.8N131 L136 I137 D200 R201N131-P133 WeakPolarHBondContact OD1-CD 3.48Å; P133-L136 PolarHBondContact O-N 3.25Å; P133-I137 WeakPolarHBondContact O-CG1 3.38Å; P133-I137 PolarHBondContact O-N 2.92Å; P133-I137 VanDerWaalsContact O-N 3.12Å; P133-D200 VanDerWaalsContact CG-OD2 3.32Å; P133-D200 WeakPolarHBondContact CG-OD2 3.3Å; P133-R201 VanDerWaalsContact CB-NH2 3.3Å
134N88.4Confident88.5Confident13 Ų1338.9 Ų38.97%0.0719%0.188CC..Hα-helixtrans-74.3-26.5175.1-69.8-9.3000112.4M129 N131 G132 I137 A138 F394M129-N134 WeakPolarHBondContact O-CB 3.39Å; M129-N134 PolarHBondContact O-ND2 3.37Å; N131-N134 PolarHBondContact ND2-ND2 2.87Å; N131-N134 PolarHBondContact O-N 3.34Å; N131-N134 VanDerWaalsContact OD1-CB 3.24Å; N131-N134 WeakPolarHBondContact OD1-CB 3.34Å; N131-N134 PolarHBondContact OD1-N 3.43Å; N131-N134 PolarHBondContact OD1-ND2 2.86Å; G132-N134 VanDerWaalsContact C-N 3.3Å; G132-N134 PolarHBondContact O-N 2.92Å; N134-I137 PolarHBondContact O-N 3.29Å; N134-A138 WeakPolarHBondContact O-CB 3.47Å; N134-A138 PolarHBondContact O-N 2.82Å; N134-F394 WeakPolarHBondContact OD1-CZ 3.41Å
135A90.7Very high88.8Confident12 Ų1232.1 Ų32.110%0.09916%0.164CC..Hα-helixtrans-67.9-37.7171.300000111.6N131 G132 A138 S139 I216 T220 I224N131-A135 PolarHBondContact O-N 2.82Å; G132-A135 WeakPolarHBondContact O-CB 3.28Å; G132-A135 PolarHBondContact O-N 3.09Å; A135-A138 WeakPolarHBondContact O-CB 3.35Å; A135-A138 PolarHBondContact O-N 3.44Å; A135-S139 PolarHBondContact O-N 3.35Å; A135-I216 HydrophobicContact CB-CD1 4.04Å; A135-I216 HydrophobicContact CB-CG1 4.28Å; A135-I216 HydrophobicContact CB-CG2 4.15Å; A135-T220 HydrophobicContact CB-CG2 4.29Å; A135-I224 HydrophobicContact CB-CD1 3.89Å
136L90.8Very high89.2Confident1 Ų129.4 Ų29.41%0.00515%0.152CC..Hα-helixtrans-63.6-42.9170.8-68.6172.2000111.6G132 P133 A138 S139 L140 N193 A196 L197 T220 E223 I224 I227G132-L136 PolarHBondContact O-N 3.36Å; G132-L136 VanDerWaalsContact O-N 3.11Å; P133-L136 PolarHBondContact O-N 3.25Å; L136-A138 VanDerWaalsContact C-N 3.3Å; L136-A138 PolarHBondContact O-N 2.83Å; L136-S139 WeakPolarHBondContact O-CB 3.33Å; L136-S139 PolarHBondContact O-N 2.99Å; L136-L140 PolarHBondContact O-N 3.47Å; L136-N193 PolarHBondContact O-OD1 3.27Å; L136-A196 HydrophobicContact CD1-CB 4.17Å; L136-A196 HydrophobicContact CD2-CB 4.17Å; L136-L197 HydrophobicContact CB-CD2 3.9Å; L136-L197 HydrophobicContact CB-CG 4.31Å; L136-L197 HydrophobicContact CD1-CD2 4.17Å; L136-T220 HydrophobicContact CG-CG2 4.27Å; L136-E223 HydrophobicContact CD2-CG 4.41Å; L136-I224 HydrophobicContact CD2-CD1 4.46Å; L136-I224 HydrophobicContact CD2-CG1 3.8Å; L136-I227 HydrophobicContact CD2-CD1 4.21Å
137I91.2Very high89.8Confident12 Ų1227.1 Ų27.16%0.06214%0.139CC..Hα-helixtrans-60.6-39.8173.5-68.6168.4000111.2L119 I123 P133 N134 L140 A141 L197 L387 F394L119-I137 HydrophobicContact CD1-CG2 4.19Å; L119-I137 HydrophobicContact CD2-CG2 3.8Å; L119-I137 HydrophobicContact CG-CG2 4.23Å; I123-I137 HydrophobicContact CD1-CG2 4.1Å; P133-I137 WeakPolarHBondContact O-CG1 3.38Å; P133-I137 PolarHBondContact O-N 2.92Å; P133-I137 VanDerWaalsContact O-N 3.12Å; N134-I137 PolarHBondContact O-N 3.29Å; I137-L140 PolarHBondContact O-N 3.43Å; I137-A141 WeakPolarHBondContact O-CB 3.36Å; I137-A141 PolarHBondContact O-N 3.32Å; I137-L197 HydrophobicContact CG1-CD2 4.24Å; I137-L387 HydrophobicContact CD1-CD1 4.38Å; I137-L387 HydrophobicContact CD1-CD2 4.06Å; I137-L387 HydrophobicContact CG2-CD1 3.51Å; I137-F394 HydrophobicContact CD1-CE2 4.21Å; I137-F394 HydrophobicContact CD1-CZ 4.2Å
138A93.3Very high90.4Very high19 Ų1920.8 Ų20.816%0.15711%0.112CC..Hα-helixtrans-65.9-41.2175.100000111.8L120 I123 N134 A135 L136 L140 A141 L142L120-A138 HydrophobicContact CD2-CB 3.83Å; L120-A138 WeakPolarHBondContact CD2-O 3.49Å; I123-A138 HydrophobicContact CD1-CB 4Å; I123-A138 HydrophobicContact CG2-CB 4.36Å; N134-A138 WeakPolarHBondContact O-CB 3.47Å; N134-A138 PolarHBondContact O-N 2.82Å; A135-A138 WeakPolarHBondContact O-CB 3.35Å; A135-A138 PolarHBondContact O-N 3.44Å; L136-A138 VanDerWaalsContact C-N 3.3Å; L136-A138 PolarHBondContact O-N 2.83Å; A138-L140 VanDerWaalsContact C-N 3.31Å; A138-L140 PolarHBondContact O-N 3.43Å; A138-A141 PolarHBondContact O-N 2.87Å; A138-L142 PolarHBondContact O-N 3.45Å
139S94.9Very high91.2Very high7 Ų725.1 Ų25.15%0.04913%0.125CC..Hα-helixtrans-59.5-42.9173.6-178.30000111.8A135 L136 L142 G143 N193 W228A135-S139 PolarHBondContact O-N 3.35Å; L136-S139 WeakPolarHBondContact O-CB 3.33Å; L136-S139 PolarHBondContact O-N 2.99Å; S139-L142 PolarHBondContact O-N 3Å; S139-G143 PolarHBondContact O-N 3.17Å; S139-G143 VanDerWaalsContact O-N 3.11Å; S139-N193 PolarHBondContact OG-ND2 3.3Å; S139-W228 PolarHBondContact OG-NE1 3.49Å
140L92.7Very high91.8Very high9 Ų926.4 Ų26.45%0.04713%0.132CC..Hα-helixtrans-61.3-49.1175.9176.563.8000111.1L136 I137 A138 L142 G143 D144 T190 N193 L197L136-L140 PolarHBondContact O-N 3.47Å; I137-L140 PolarHBondContact O-N 3.43Å; A138-L140 VanDerWaalsContact C-N 3.31Å; A138-L140 PolarHBondContact O-N 3.43Å; L140-L142 VanDerWaalsContact C-N 3.27Å; L140-L142 PolarHBondContact O-N 3.15Å; L140-G143 PolarHBondContact O-N 3.23Å; L140-G143 VanDerWaalsContact O-N 3.13Å; L140-D144 VanDerWaalsContact O-CG 3.31Å; L140-D144 PolarHBondContact O-N 3.1Å; L140-T190 HydrophobicContact CD1-CG2 3.78Å; L140-N193 HydrophobicContact CB-CB 4.24Å; L140-N193 HydrophobicContact CD1-CB 4.37Å; L140-L197 HydrophobicContact CD2-CD1 4.5Å
141A95.1Very high92.1Very high1 Ų122.1 Ų22.11%0.00812%0.116CC..Hα-helixtrans-60.1-35.9178.900000112.9N116 L119 L120 I137 A138 L145N116-A141 HydrophobicContact CB-CB 4.33Å; L119-A141 HydrophobicContact CD2-CB 4Å; L119-A141 HydrophobicContact CG-CB 4.42Å; L120-A141 HydrophobicContact CD2-CB 4.05Å; L120-A141 HydrophobicContact CG-CB 3.98Å; I137-A141 WeakPolarHBondContact O-CB 3.36Å; I137-A141 PolarHBondContact O-N 3.32Å; A138-A141 PolarHBondContact O-N 2.87Å; A141-L145 WeakPolarHBondContact O-CG 3.43Å; A141-L145 PolarHBondContact O-N 2.95Å
142L96Very high92.4Very high76 Ų7620.8 Ų20.840%0.39811%0.109SC..Hα-helixtrans-68.5-42.4175.3-175.960.4000111.8L120 A138 S139 L140 L145 I146 W228L120-L142 HydrophobicContact CD1-CD1 4.47Å; A138-L142 PolarHBondContact O-N 3.45Å; S139-L142 PolarHBondContact O-N 3Å; L140-L142 VanDerWaalsContact C-N 3.27Å; L140-L142 PolarHBondContact O-N 3.15Å; L142-L145 PolarHBondContact O-N 3.38Å; L142-I146 HydrophobicContact CG-CD1 4.43Å; L142-I146 WeakPolarHBondContact O-CG1 3.36Å; L142-I146 PolarHBondContact O-N 3.43Å; L142-I146 VanDerWaalsContact O-N 3.11Å; L142-W228 HydrophobicContact CB-CZ2 4.25Å; L142-W228 HydrophobicContact CD2-CH2 3.71Å; L142-W228 HydrophobicContact CD2-CZ2 3.61Å; L142-W228 HydrophobicContact CG-CH2 3.88Å; L142-W228 HydrophobicContact CG-CZ2 3.91Å
143G95.5Very high92.9Very high0 Ų023.3 Ų23.30%013%0.125CC..Hα-helixtrans-61.8-43.8174.400000112.6S139 L140 I146 Y147 S186S139-G143 PolarHBondContact O-N 3.17Å; S139-G143 VanDerWaalsContact O-N 3.11Å; L140-G143 PolarHBondContact O-N 3.23Å; L140-G143 VanDerWaalsContact O-N 3.13Å; G143-I146 PolarHBondContact O-N 2.83Å; G143-Y147 PolarHBondContact O-N 3.17Å; G143-S186 WeakPolarHBondContact O-CB 3.42Å; G143-S186 PolarHBondContact O-OG 3.4Å; G143-S186 VanDerWaalsContact O-OG 3.1Å
144D94.9Very high93.3Very high0 Ų024.1 Ų24.10%013%0.128CC..Hα-helixtrans-61.9-41.6176.7-71.1-17000111.4L140 Y147 I148 T190 N383L140-D144 VanDerWaalsContact O-CG 3.31Å; L140-D144 PolarHBondContact O-N 3.1Å; D144-Y147 PolarHBondContact O-N 3.16Å; D144-I148 WeakPolarHBondContact O-CB 3.47Å; D144-I148 WeakPolarHBondContact O-CD1 3.31Å; D144-I148 WeakPolarHBondContact O-CG1 3.42Å; D144-I148 PolarHBondContact O-N 3.25Å; D144-T190 PolarHBondContact OD1-OG1 3.11Å; D144-N383 PolarHBondContact OD2-ND2 3.13Å
145L96.1Very high93.4Very high29 Ų2924.8 Ų24.815%0.15213%0.132CC..Hα-helixtrans-61.3-46.1174.7-79.9176.1000112.4L113 N116 L120 A141 L142 Y147 I148 F149L113-L145 HydrophobicContact CD1-CD2 3.73Å; N116-L145 HydrophobicContact CB-CD1 4.35Å; N116-L145 HydrophobicContact CB-CD2 3.78Å; N116-L145 HydrophobicContact CB-CG 3.69Å; L120-L145 HydrophobicContact CD1-CD1 3.53Å; A141-L145 WeakPolarHBondContact O-CG 3.43Å; A141-L145 PolarHBondContact O-N 2.95Å; L142-L145 PolarHBondContact O-N 3.38Å; L145-Y147 VanDerWaalsContact C-N 3.29Å; L145-Y147 PolarHBondContact O-N 3.28Å; L145-I148 PolarHBondContact O-N 3.18Å; L145-F149 WeakPolarHBondContact O-CB 3.46Å; L145-F149 PolarHBondContact O-N 3.16Å
146I95.5Very high93.3Very high47 Ų4725 Ų2524%0.24113%0.134CC..Hα-helixtrans-60.3-43.7177-66.6166.5000109.8L142 G143 I150 L182 S186 W228L142-I146 HydrophobicContact CG-CD1 4.43Å; L142-I146 WeakPolarHBondContact O-CG1 3.36Å; L142-I146 PolarHBondContact O-N 3.43Å; L142-I146 VanDerWaalsContact O-N 3.11Å; G143-I146 PolarHBondContact O-N 2.83Å; I146-I150 HydrophobicContact CG2-CD1 3.79Å; I146-I150 WeakPolarHBondContact O-CB 3.47Å; I146-I150 VanDerWaalsContact O-CG1 3.31Å; I146-I150 WeakPolarHBondContact O-CG1 3.23Å; I146-I150 PolarHBondContact O-N 3.46Å; I146-L182 HydrophobicContact CG2-CB 4.47Å; I146-S186 WeakPolarHBondContact CG2-OG 3.49Å; I146-W228 HydrophobicContact CD1-CH2 3.73Å; I146-W228 HydrophobicContact CD1-CZ3 4.13Å
147Y94.6Very high93.3Very high11 Ų1130 Ų304%0.04315%0.153CC..Hα-helixtrans-61.7-54178.4-170.9-101.8000111.4G143 D144 L145 F149 I150 D151 Q183 S186 V187 T377G143-Y147 PolarHBondContact O-N 3.17Å; D144-Y147 PolarHBondContact O-N 3.16Å; L145-Y147 VanDerWaalsContact C-N 3.29Å; L145-Y147 PolarHBondContact O-N 3.28Å; Y147-F149 VanDerWaalsContact C-N 3.34Å; Y147-F149 PolarHBondContact O-N 3.23Å; Y147-I150 PolarHBondContact O-N 3.03Å; Y147-D151 HydrophobicContact CD1-CB 4.34Å; Y147-D151 HydrophobicContact CE1-CB 4.17Å; Y147-D151 HydrophobicContact CE2-CB 4.4Å; Y147-D151 WeakPolarHBondContact O-CB 3.47Å; Y147-D151 PolarHBondContact O-N 3.09Å; Y147-Q183 HydrophobicContact CE2-CB 4.18Å; Y147-Q183 HydrophobicContact CE2-CG 4.2Å; Y147-S186 PolarHBondContact N-OG 2.83Å; Y147-V187 HydrophobicContact CD2-CG2 4.02Å; Y147-V187 HydrophobicContact CE2-CG2 3.65Å; Y147-T377 HydrophobicContact CD1-CG2 4.33Å; Y147-T377 HydrophobicContact CE1-CG2 3.57Å
148I95.3Very high93.2Very high1 Ų133.8 Ų33.81%0.00517%0.169CC..Hα-helixtrans-60.4-44-177.5-69.8160.1000111.3F109 D144 L145 I150 I152F109-I148 HydrophobicContact CD2-CG2 3.81Å; F109-I148 HydrophobicContact CE2-CG2 4.37Å; D144-I148 WeakPolarHBondContact O-CB 3.47Å; D144-I148 WeakPolarHBondContact O-CD1 3.31Å; D144-I148 WeakPolarHBondContact O-CG1 3.42Å; D144-I148 PolarHBondContact O-N 3.25Å; L145-I148 PolarHBondContact O-N 3.18Å; I148-I150 VanDerWaalsContact C-N 3.29Å; I148-I150 PolarHBondContact O-N 3.45Å; I148-I152 HydrophobicContact CG2-CD1 3.91Å; I148-I152 PolarHBondContact O-N 3.22Å
149F94.4Very high92.8Very high138 Ų13833 Ų3361%0.60516%0.163SC*.Hα-helixtrans-64.9-33.7-176.4-173.6-100.3000112.7L145 Y147 P153L145-F149 WeakPolarHBondContact O-CB 3.46Å; L145-F149 PolarHBondContact O-N 3.16Å; Y147-F149 VanDerWaalsContact C-N 3.34Å; Y147-F149 PolarHBondContact O-N 3.23Å; F149-P153 VanDerWaalsContact O-CD 3.28Å; F149-P153 WeakPolarHBondContact O-CD 3.42Å; F149-P153 VanDerWaalsContact O-CG 3.31Å; F149-P153 WeakPolarHBondContact O-CG 3.49Å
150I91.8Very high92.5Very high31 Ų3137.3 Ų37.316%0.15918%0.184CC..Hα-helixtrans-96.1-45.7-174.7-62.2173.4000111.2I146 Y147 I148 I154 V179 L182I146-I150 HydrophobicContact CG2-CD1 3.79Å; I146-I150 WeakPolarHBondContact O-CB 3.47Å; I146-I150 VanDerWaalsContact O-CG1 3.31Å; I146-I150 WeakPolarHBondContact O-CG1 3.23Å; I146-I150 PolarHBondContact O-N 3.46Å; Y147-I150 PolarHBondContact O-N 3.03Å; I148-I150 VanDerWaalsContact C-N 3.29Å; I148-I150 PolarHBondContact O-N 3.45Å; I150-I154 WeakPolarHBondContact O-CG1 3.34Å; I150-V179 HydrophobicContact CG2-CB 4.17Å; I150-V179 HydrophobicContact CG2-CG1 3.98Å; I150-V179 HydrophobicContact CG2-CG2 3.82Å; I150-L182 HydrophobicContact CD1-CB 3.68Å; I150-L182 HydrophobicContact CD1-CD1 3.27Å; I150-L182 HydrophobicContact CD1-CG 4.07Å
151D91.5Very high92.1Very high5 Ų538.8 Ų38.83%0.02720%0.198CC..Hα-helixtrans-67.9-49.8-172.2-17580000111.9Y147 I154 N155 Q183 T377Y147-D151 HydrophobicContact CD1-CB 4.34Å; Y147-D151 HydrophobicContact CE1-CB 4.17Å; Y147-D151 HydrophobicContact CE2-CB 4.4Å; Y147-D151 WeakPolarHBondContact O-CB 3.47Å; Y147-D151 PolarHBondContact O-N 3.09Å; D151-I154 PolarHBondContact O-N 2.96Å; D151-N155 WeakPolarHBondContact O-CB 3.44Å; D151-N155 PolarHBondContact O-N 3.4Å; D151-N155 PolarHBondContact O-ND2 3.35Å; D151-N155 VanDerWaalsContact O-ND2 3.07Å; D151-N155 PolarHBondContact OD1-ND2 2.92Å; D151-N155 PolarHBondContact OD2-ND2 3.16Å; D151-Q183 HydrophobicContact CB-CG 4.3Å; D151-Q183 PolarHBondContact OD1-NE2 2.95Å; D151-T377 WeakPolarHBondContact OD2-CG2 3.34Å
152I92.1Very high91.5Very high10 Ų1042 Ų425%0.05122%0.221CC..Hα-helixtrans-66-50.4-170.2-63.4-177.3000112.3V108 F109 I148 I154 N155 A156 T377V108-I152 HydrophobicContact CB-CD1 4.34Å; V108-I152 HydrophobicContact CG1-CD1 3.86Å; F109-I152 HydrophobicContact CB-CD1 3.89Å; F109-I152 HydrophobicContact CB-CG2 4.12Å; F109-I152 HydrophobicContact CD2-CB 4.08Å; F109-I152 HydrophobicContact CD2-CD1 4.24Å; F109-I152 HydrophobicContact CD2-CG2 4.21Å; I148-I152 HydrophobicContact CG2-CD1 3.91Å; I148-I152 PolarHBondContact O-N 3.22Å; I152-I154 VanDerWaalsContact C-N 3.31Å; I152-I154 PolarHBondContact O-N 3.38Å; I152-N155 PolarHBondContact O-N 2.92Å; I152-A156 WeakPolarHBondContact O-CB 3.44Å; I152-A156 PolarHBondContact O-N 2.81Å; I152-T377 HydrophobicContact CD1-CG2 4.46Å; I152-T377 HydrophobicContact CG1-CG2 3.97Å
153P92.3Very high91Very high59 Ų5945.1 Ų45.138%0.38323%0.227SC..Hα-helixtrans-61.3-40.5-178.8-24.836.5000112.6F109 F149 Y157F109-P153 HydrophobicContact CE2-CG 4.18Å; F149-P153 VanDerWaalsContact O-CD 3.28Å; F149-P153 WeakPolarHBondContact O-CD 3.42Å; F149-P153 VanDerWaalsContact O-CG 3.31Å; F149-P153 WeakPolarHBondContact O-CG 3.49Å; P153-Y157 WeakPolarHBondContact O-CB 3.37Å; P153-Y157 PolarHBondContact O-N 2.96Å
154I91.9Very high90.6Very high25 Ų2545.7 Ų45.713%0.12823%0.229CC..Hα-helixtrans-69.4-45.1-178.4-59.7-67.3000110.8I150 D151 I152 Y157 K158 F164 P165 L175 V179I150-I154 WeakPolarHBondContact O-CG1 3.34Å; D151-I154 PolarHBondContact O-N 2.96Å; I152-I154 VanDerWaalsContact C-N 3.31Å; I152-I154 PolarHBondContact O-N 3.38Å; I154-Y157 PolarHBondContact O-N 3.42Å; I154-K158 VanDerWaalsContact O-CB 3.3Å; I154-K158 WeakPolarHBondContact O-CB 3.41Å; I154-K158 PolarHBondContact O-N 3.19Å; I154-F164 HydrophobicContact CG2-CE2 4.37Å; I154-P165 HydrophobicContact CD1-CG 3.65Å; I154-P165 HydrophobicContact CG2-CG 4.41Å; I154-L175 HydrophobicContact CD1-CD1 4.39Å; I154-V179 HydrophobicContact CB-CG1 4.44Å; I154-V179 HydrophobicContact CD1-CG2 4.28Å; I154-V179 HydrophobicContact CG1-CG1 4.37Å; I154-V179 HydrophobicContact CG1-CG2 3.93Å; I154-V179 HydrophobicContact CG2-CG1 4.21Å
155N89.8Confident90.2Very high27 Ų2745.9 Ų45.914%0.14423%0.231CC..Hα-helixtrans-68.4-38.6178.3-74.7-44.3000112.2D151 I152 K158 L159 I373D151-N155 WeakPolarHBondContact O-CB 3.44Å; D151-N155 PolarHBondContact O-N 3.4Å; D151-N155 PolarHBondContact O-ND2 3.35Å; D151-N155 VanDerWaalsContact O-ND2 3.07Å; D151-N155 PolarHBondContact OD1-ND2 2.92Å; D151-N155 PolarHBondContact OD2-ND2 3.16Å; I152-N155 PolarHBondContact O-N 2.92Å; N155-K158 PolarHBondContact O-N 3.12Å; N155-L159 WeakPolarHBondContact O-CB 3.34Å; N155-L159 PolarHBondContact O-N 3.42Å; N155-I373 WeakPolarHBondContact ND2-CG2 3.49Å
156A90.3Very high89.7Confident17 Ų1750 Ų5014%0.1425%0.248CC..Hα-helixtrans-63-45.7174.700000111.3I152 L159 L160I152-A156 WeakPolarHBondContact O-CB 3.44Å; I152-A156 PolarHBondContact O-N 2.81Å; A156-L159 PolarHBondContact O-N 2.91Å; A156-L160 WeakPolarHBondContact O-CB 3.4Å; A156-L160 VanDerWaalsContact O-CG 3.32Å; A156-L160 WeakPolarHBondContact O-CG 3.36Å; A156-L160 PolarHBondContact O-N 3.34Å
157Y90.4Very high89Confident105 Ų10548.6 Ų48.641%0.41224%0.241SC..Hα-helixtrans-60.3-48175.4-174.9-85.3000111.3P153 I154 L159 L160 A161 R163 P165P153-Y157 WeakPolarHBondContact O-CB 3.37Å; P153-Y157 PolarHBondContact O-N 2.96Å; I154-Y157 PolarHBondContact O-N 3.42Å; Y157-L159 VanDerWaalsContact C-N 3.28Å; Y157-L159 PolarHBondContact O-N 3.07Å; Y157-L160 PolarHBondContact O-N 3.28Å; Y157-A161 HydrophobicContact CD1-CB 4.08Å; Y157-A161 HydrophobicContact CE1-CB 3.72Å; Y157-A161 HydrophobicContact CE2-CB 4.26Å; Y157-A161 HydrophobicContact CG-CB 4.5Å; Y157-A161 WeakPolarHBondContact O-CB 3.39Å; Y157-A161 PolarHBondContact O-N 3.19Å; Y157-R163 WeakPolarHBondContact CD1-O 3.44Å; Y157-P165 HydrophobicContact CD1-CB 3.77Å; Y157-P165 HydrophobicContact CD1-CG 4.2Å; Y157-P165 VanDerWaalsContact CE1-CA 3.49Å; Y157-P165 HydrophobicContact CE1-CB 3.87Å; Y157-P165 HydrophobicContact CG-CB 4.21Å
158K87.8Confident88.4Confident92 Ų9253.9 Ų53.940%0.427%0.27SS..Hα-helixtrans-58.5-39.9179-174.6178.9177.3-177.60112.1I154 N155 S162I154-K158 VanDerWaalsContact O-CB 3.3Å; I154-K158 WeakPolarHBondContact O-CB 3.41Å; I154-K158 PolarHBondContact O-N 3.19Å; N155-K158 PolarHBondContact O-N 3.12Å; K158-S162 WeakPolarHBondContact O-CA 3.25Å; K158-S162 PolarHBondContact O-N 3.38Å; K158-S162 VanDerWaalsContact O-N 3.08Å
159L86.3Confident87.9Confident4 Ų459.5 Ų59.52%0.02130%0.296CS..Hα-helixtrans-70-41.9178.2179.160000112.9I93 K98 N101 N155 A156 Y157I93-L159 HydrophobicContact CD1-CD1 3.63Å; I93-L159 HydrophobicContact CG2-CD1 4.22Å; K98-L159 HydrophobicContact CB-CG 4.44Å; K98-L159 HydrophobicContact CG-CD1 3.92Å; K98-L159 HydrophobicContact CG-CG 4.18Å; N101-L159 HydrophobicContact CB-CD2 3.64Å; N101-L159 VanDerWaalsContact ND2-CD2 3.27Å; N101-L159 WeakPolarHBondContact ND2-CD2 3.35Å; N155-L159 WeakPolarHBondContact O-CB 3.34Å; N155-L159 PolarHBondContact O-N 3.42Å; A156-L159 PolarHBondContact O-N 2.91Å; Y157-L159 VanDerWaalsContact C-N 3.28Å; Y157-L159 PolarHBondContact O-N 3.07Å
160L87.3Confident87.5Confident96 Ų9662.7 Ų62.750%0.50330%0.304SS..Hα-helixtrans-78.1-53-176.5-68.6172.8000111.9T102 A156 Y157 S162T102-L160 HydrophobicContact CG2-CD1 4.1Å; A156-L160 WeakPolarHBondContact O-CB 3.4Å; A156-L160 VanDerWaalsContact O-CG 3.32Å; A156-L160 WeakPolarHBondContact O-CG 3.36Å; A156-L160 PolarHBondContact O-N 3.34Å; Y157-L160 PolarHBondContact O-N 3.28Å; L160-S162 VanDerWaalsContact C-N 3.35Å
161A85.8Confident87.4Confident41 Ų4165.4 Ų65.434%0.33932%0.315SS..Hα-helixtrans-81.8-13.9-176.200000113.1Y157 R163Y157-A161 HydrophobicContact CD1-CB 4.08Å; Y157-A161 HydrophobicContact CE1-CB 3.72Å; Y157-A161 HydrophobicContact CE2-CB 4.26Å; Y157-A161 HydrophobicContact CG-CB 4.5Å; Y157-A161 WeakPolarHBondContact O-CB 3.39Å; Y157-A161 PolarHBondContact O-N 3.19Å; A161-R163 PolarHBondContact O-N 3.29Å
162S82.8Confident87.3Confident69 Ų6965.2 Ų65.248%0.48331%0.313SS..SBendtrans53.424.7-173.6-51.10000113.2K158 L160K158-S162 WeakPolarHBondContact O-CA 3.25Å; K158-S162 PolarHBondContact O-N 3.38Å; K158-S162 VanDerWaalsContact O-N 3.08Å; L160-S162 VanDerWaalsContact C-N 3.35Å
163R84.6Confident87.2Confident141 Ų14167.7 Ų67.753%0.53233%0.327SS..SBendtrans-137.6159.2-179.3-68.4-170.1-176.2-168.91.4110.2Y157 A161Y157-R163 WeakPolarHBondContact CD1-O 3.44Å; A161-R163 PolarHBondContact O-N 3.29Å
164F86.8Confident87.2Confident11 Ų1167.5 Ų67.55%0.04833%0.326CS..  trans-80.7138.4172.8-165.8-94.3000109.3I154 F166 D167 G172 L175 C176 M244 C257I154-F164 HydrophobicContact CG2-CE2 4.37Å; F164-F166 PolarHBondContact O-N 3.05Å; F164-D167 PolarHBondContact O-N 3.33Å; F164-G172 WeakPolarHBondContact CE1-O 3.48Å; F164-L175 HydrophobicContact CE1-CB 4.01Å; F164-L175 HydrophobicContact CZ-CB 4.14Å; F164-C176 HydrophobicContact CE1-CB 4.09Å; F164-C176 HydrophobicContact CZ-CB 4.04Å; F164-M244 HydrophobicContact CB-CE 4.33Å; F164-M244 HydrophobicContact CD1-CE 4.09Å; F164-M244 HydrophobicContact CD1-SD 3.95Å; F164-M244 HydrophobicContact CE1-SD 4.42Å; F164-M244 HydrophobicContact CG-CE 4.46Å; F164-M244 HydrophobicContact CG-SD 4.3Å; F164-C257 HydrophobicContact CD1-CB 4.34Å; F164-C257 HydrophobicContact CD2-CB 3.4Å; F164-C257 VanDerWaalsContact CD2-CB 3.4Å; F164-C257 HydrophobicContact CE1-CB 4.36Å; F164-C257 HydrophobicContact CE2-CB 3.43Å; F164-C257 VanDerWaalsContact CE2-CB 3.43Å; F164-C257 HydrophobicContact CG-CB 3.89Å; F164-C257 HydrophobicContact CZ-CB 3.94Å
165P86.6Confident87.3Confident5 Ų567.4 Ų67.43%0.03233%0.325CS..THydrogen-bonded Turntrans-63.7134.5-178.224.8-33.1000111.4I154 Y157 D167 L175I154-P165 HydrophobicContact CD1-CG 3.65Å; I154-P165 HydrophobicContact CG2-CG 4.41Å; Y157-P165 HydrophobicContact CD1-CB 3.77Å; Y157-P165 HydrophobicContact CD1-CG 4.2Å; Y157-P165 VanDerWaalsContact CE1-CA 3.49Å; Y157-P165 HydrophobicContact CE1-CB 3.87Å; Y157-P165 HydrophobicContact CG-CB 4.21Å; P165-D167 VanDerWaalsContact C-N 3.27Å; P165-D167 PolarHBondContact O-N 2.97Å; P165-L175 HydrophobicContact CG-CD1 4.45Å
166F84.9Confident87.4Confident116 Ų11666.1 Ų66.151%0.50932%0.319SS..THydrogen-bonded Turntrans57.135.7178.3-46.9-79000113.9F164 D168 H169 F171 G172 L175F164-F166 PolarHBondContact O-N 3.05Å; F166-D168 PolarHBondContact O-N 3.2Å; F166-H169 PolarHBondContact O-N 3.35Å; F166-F171 HydrophobicContact CB-CD1 4.12Å; F166-F171 AromaticContact CD2-CD1 3.54Å; F166-F171 HydrophobicContact CD2-CD1 3.54Å; F166-F171 AromaticContact CD2-CE1 3.71Å; F166-F171 HydrophobicContact CD2-CE1 3.71Å; F166-F171 HydrophobicContact CE2-CD1 4.04Å; F166-F171 AromaticContact CE2-CE1 3.78Å; F166-F171 HydrophobicContact CE2-CE1 3.78Å; F166-F171 AromaticContact CG-CD1 3.81Å; F166-F171 HydrophobicContact CG-CD1 3.81Å; F166-F171 HydrophobicContact CG-CE1 4.39Å; F166-G172 VanDerWaalsContact O-CA 3.28Å; F166-G172 WeakPolarHBondContact O-CA 3.29Å; F166-G172 PolarHBondContact O-N 2.88Å; F166-L175 HydrophobicContact CD2-CD1 3.86Å; F166-L175 HydrophobicContact CE2-CD1 4.39Å
167D82.1Confident87.6Confident17 Ų1768.3 Ų68.39%0.09133%0.325CS..THydrogen-bonded Turntrans-56.7-29-178.856.4-22.1000114.2F164 P165 M244 R255F164-D167 PolarHBondContact O-N 3.33Å; P165-D167 VanDerWaalsContact C-N 3.27Å; P165-D167 PolarHBondContact O-N 2.97Å; D167-M244 HydrophobicContact CB-CE 3.67Å; D167-R255 HydrophobicContact CB-CB 4.34Å; D167-R255 VanDerWaalsContact O-CD 3.29Å; D167-R255 WeakPolarHBondContact O-CD 3.03Å; D167-R255 PolarHBondContact O-NH1 3.29Å
168D81.3Confident87.8Confident121 Ų12166.8 Ų66.865%0.64732%0.324SS*.THydrogen-bonded Turntrans-80-12.9177.9-61.6-36000114.3F166F166-D168 PolarHBondContact O-N 3.2Å
169H84.9Confident88.1Confident120 Ų12062.7 Ų62.756%0.55631%0.306SS*.SBendtrans-111.3157.5-173.3-71.867.5000112.8F166 F171 G172F166-H169 PolarHBondContact O-N 3.35Å; H169-F171 PolarHBondContact O-N 3.18Å; H169-F171 VanDerWaalsContact O-N 3.13Å; H169-G172 PolarHBondContact O-N 3.37Å
170W87.3Confident88.4Confident205 Ų20563 Ų6378%0.77731%0.308SS*.Hα-helixtrans-56.9-29173.775.5-93.2000112.5G172 L173 C174W170-G172 VanDerWaalsContact C-N 3.29Å; W170-G172 PolarHBondContact O-N 2.83Å; W170-L173 WeakPolarHBondContact O-CB 3.41Å; W170-L173 PolarHBondContact O-N 3.36Å; W170-C174 HydrophobicContact CZ3-CB 4.37Å; W170-C174 PolarHBondContact O-N 2.74Å
171F89Confident88.9Confident88 Ų8860.2 Ų60.239%0.38629%0.292SS..Hα-helixtrans-61.8-34.8175.6-172.6-113.1000112.6F166 H169 L173 C174 L175F166-F171 HydrophobicContact CB-CD1 4.12Å; F166-F171 AromaticContact CD2-CD1 3.54Å; F166-F171 HydrophobicContact CD2-CD1 3.54Å; F166-F171 AromaticContact CD2-CE1 3.71Å; F166-F171 HydrophobicContact CD2-CE1 3.71Å; F166-F171 HydrophobicContact CE2-CD1 4.04Å; F166-F171 AromaticContact CE2-CE1 3.78Å; F166-F171 HydrophobicContact CE2-CE1 3.78Å; F166-F171 AromaticContact CG-CD1 3.81Å; F166-F171 HydrophobicContact CG-CD1 3.81Å; F166-F171 HydrophobicContact CG-CE1 4.39Å; H169-F171 PolarHBondContact O-N 3.18Å; H169-F171 VanDerWaalsContact O-N 3.13Å; F171-L173 PolarHBondContact O-N 3Å; F171-C174 WeakPolarHBondContact O-CB 3.08Å; F171-C174 PolarHBondContact O-N 3.42Å; F171-L175 HydrophobicContact CD1-CD1 3.77Å; F171-L175 HydrophobicContact CD1-CG 4.18Å; F171-L175 HydrophobicContact CE1-CD1 3.42Å; F171-L175 VanDerWaalsContact CE1-CD1 3.42Å; F171-L175 HydrophobicContact CE1-CD2 4.28Å; F171-L175 HydrophobicContact CE1-CG 3.87Å; F171-L175 HydrophobicContact CE2-CG 4.47Å; F171-L175 HydrophobicContact CZ-CD1 4.03Å; F171-L175 HydrophobicContact CZ-CD2 4.01Å; F171-L175 HydrophobicContact CZ-CG 4.01Å; F171-L175 WeakPolarHBondContact O-CG 3.29Å; F171-L175 PolarHBondContact O-N 3.48Å
172G89.3Confident89.3Confident0 Ų060 Ų600%029%0.286CS..Hα-helixtrans-63.9-38174.900000112.8F164 F166 H169 W170 L175 C176F164-G172 WeakPolarHBondContact CE1-O 3.48Å; F166-G172 VanDerWaalsContact O-CA 3.28Å; F166-G172 WeakPolarHBondContact O-CA 3.29Å; F166-G172 PolarHBondContact O-N 2.88Å; H169-G172 PolarHBondContact O-N 3.37Å; W170-G172 VanDerWaalsContact C-N 3.29Å; W170-G172 PolarHBondContact O-N 2.83Å; G172-L175 PolarHBondContact O-N 2.88Å; G172-C176 VanDerWaalsContact O-CB 3.27Å; G172-C176 WeakPolarHBondContact O-CB 3.25Å; G172-C176 PolarHBondContact O-N 2.68Å
173L90.9Very high89.9Confident63 Ų6358.5 Ų58.533%0.3327%0.271SS..Hα-helixtrans-65.2-43173.6177.961.5000111.6W170 F171 C176 K177 D243 M244W170-L173 WeakPolarHBondContact O-CB 3.41Å; W170-L173 PolarHBondContact O-N 3.36Å; F171-L173 PolarHBondContact O-N 3Å; L173-C176 WeakPolarHBondContact O-CB 3.2Å; L173-C176 PolarHBondContact O-N 2.85Å; L173-K177 PolarHBondContact O-N 2.74Å; L173-D243 WeakPolarHBondContact CD1-OD1 3.27Å; L173-M244 HydrophobicContact CB-CG 4.38Å; L173-M244 HydrophobicContact CD1-CB 4.23Å; L173-M244 HydrophobicContact CD1-CG 4.1Å
174C92.3Very high90.4Very high54 Ų5452.6 Ų52.637%0.36525%0.249SC..Hα-helixtrans-58.9-50.3175.4-1760000111W170 F171 C176 K177 L178W170-C174 HydrophobicContact CZ3-CB 4.37Å; W170-C174 PolarHBondContact O-N 2.74Å; F171-C174 WeakPolarHBondContact O-CB 3.08Å; F171-C174 PolarHBondContact O-N 3.42Å; C174-C176 VanDerWaalsContact C-N 3.31Å; C174-C176 PolarHBondContact O-N 2.95Å; C174-K177 PolarHBondContact O-N 3.11Å; C174-L178 WeakPolarHBondContact O-CB 3.31Å; C174-L178 PolarHBondContact O-N 2.9Å
175L92.3Very high90.8Very high23 Ų2352.1 Ų52.112%0.1225%0.247CC..Hα-helixtrans-60.5-39.3176.1-72.3179.2000112.5I154 F164 P165 F166 F171 G172 K177 L178 V179I154-L175 HydrophobicContact CD1-CD1 4.39Å; F164-L175 HydrophobicContact CE1-CB 4.01Å; F164-L175 HydrophobicContact CZ-CB 4.14Å; P165-L175 HydrophobicContact CG-CD1 4.45Å; F166-L175 HydrophobicContact CD2-CD1 3.86Å; F166-L175 HydrophobicContact CE2-CD1 4.39Å; F171-L175 HydrophobicContact CD1-CD1 3.77Å; F171-L175 HydrophobicContact CD1-CG 4.18Å; F171-L175 HydrophobicContact CE1-CD1 3.42Å; F171-L175 VanDerWaalsContact CE1-CD1 3.42Å; F171-L175 HydrophobicContact CE1-CD2 4.28Å; F171-L175 HydrophobicContact CE1-CG 3.87Å; F171-L175 HydrophobicContact CE2-CG 4.47Å; F171-L175 HydrophobicContact CZ-CD1 4.03Å; F171-L175 HydrophobicContact CZ-CD2 4.01Å; F171-L175 HydrophobicContact CZ-CG 4.01Å; F171-L175 WeakPolarHBondContact O-CG 3.29Å; F171-L175 PolarHBondContact O-N 3.48Å; G172-L175 PolarHBondContact O-N 2.88Å; L175-K177 PolarHBondContact O-N 3.25Å; L175-L178 PolarHBondContact O-N 2.85Å; L175-V179 HydrophobicContact CB-CG2 4.32Å; L175-V179 HydrophobicContact CD2-CG2 4.23Å; L175-V179 WeakPolarHBondContact O-CB 3.08Å; L175-V179 WeakPolarHBondContact O-CG2 3.18Å; L175-V179 PolarHBondContact O-N 3.45Å
176C93.4Very high91.3Very high0 Ų052 Ų520%025%0.246CC..Hα-helixtrans-60.1-34.2179.7177.20000112.8F164 G172 L173 C174 P180 D243 M244 C257F164-C176 HydrophobicContact CE1-CB 4.09Å; F164-C176 HydrophobicContact CZ-CB 4.04Å; G172-C176 VanDerWaalsContact O-CB 3.27Å; G172-C176 WeakPolarHBondContact O-CB 3.25Å; G172-C176 PolarHBondContact O-N 2.68Å; L173-C176 WeakPolarHBondContact O-CB 3.2Å; L173-C176 PolarHBondContact O-N 2.85Å; C174-C176 VanDerWaalsContact C-N 3.31Å; C174-C176 PolarHBondContact O-N 2.95Å; C176-P180 WeakPolarHBondContact O-CD 3.37Å; C176-P180 VanDerWaalsContact O-CG 3.24Å; C176-P180 WeakPolarHBondContact O-CG 3.43Å; C176-D243 VanDerWaalsContact SG-C 3.51Å; C176-M244 HydrophobicContact CB-CG 3.87Å; C176-M244 HydrophobicContact CB-SD 3.9Å; C176-C257 WeakPolarHBondContact CA-SG 3.39Å; C176-C257 HydrophobicContact CB-CB 3.71Å; C176-C257 WeakPolarHBondContact CB-SG 3.45Å; C176-C257 PolarHBondContact O-SG 2.67Å; C176-C257 WeakPolarHBondContact SG-CA 3.22Å; C176-C257 WeakPolarHBondContact SG-CB 3.11Å; C176-C257 CovalentContact SG-SG 2.03Å; C176-C257 PolarHBondContact SG-SG 2.93Å
177K94.2Very high91.7Very high63 Ų6346.7 Ų46.727%0.27422%0.223SC..Hα-helixtrans-86.8-41.4175.7-66.2-177.7175.5-66.30112.3L173 C174 L175 F181 A239 F242L173-K177 PolarHBondContact O-N 2.74Å; C174-K177 PolarHBondContact O-N 3.11Å; L175-K177 PolarHBondContact O-N 3.25Å; K177-F181 WeakPolarHBondContact O-CB 3.36Å; K177-F181 PolarHBondContact O-N 3.43Å; K177-A239 WeakPolarHBondContact CG-O 3.43Å; K177-A239 PolarHBondContact NZ-O 3.39Å; K177-F242 WeakPolarHBondContact CG-O 3.46Å; K177-F242 PolarHBondContact NZ-O 3.25Å
178L93.9Very high92.3Very high74 Ų7445.9 Ų45.939%0.38722%0.219SC..Hα-helixtrans-72.5-39.7-173.8-174.365.5000112.8C174 L175 F181 L182C174-L178 WeakPolarHBondContact O-CB 3.31Å; C174-L178 PolarHBondContact O-N 2.9Å; L175-L178 PolarHBondContact O-N 2.85Å; L178-F181 HydrophobicContact CD1-CD1 4.38Å; L178-F181 PolarHBondContact O-N 3.39Å; L178-L182 HydrophobicContact CD1-CD1 3.68Å; L178-L182 HydrophobicContact CD1-CG 3.94Å; L178-L182 HydrophobicContact CD2-CD1 4.25Å; L178-L182 HydrophobicContact CG-CD1 3.71Å; L178-L182 HydrophobicContact CG-CG 4.24Å; L178-L182 WeakPolarHBondContact O-CB 3.18Å; L178-L182 WeakPolarHBondContact O-CG 3.42Å; L178-L182 PolarHBondContact O-N 3.49Å
179V93.9Very high93Very high6 Ų640.2 Ų40.24%0.03619%0.189CC..Hα-helixtrans-64.7-53.6-176.2169.50000111.5I150 I154 L175 F181 L182 Q183I150-V179 HydrophobicContact CG2-CB 4.17Å; I150-V179 HydrophobicContact CG2-CG1 3.98Å; I150-V179 HydrophobicContact CG2-CG2 3.82Å; I154-V179 HydrophobicContact CB-CG1 4.44Å; I154-V179 HydrophobicContact CD1-CG2 4.28Å; I154-V179 HydrophobicContact CG1-CG1 4.37Å; I154-V179 HydrophobicContact CG1-CG2 3.93Å; I154-V179 HydrophobicContact CG2-CG1 4.21Å; L175-V179 HydrophobicContact CB-CG2 4.32Å; L175-V179 HydrophobicContact CD2-CG2 4.23Å; L175-V179 WeakPolarHBondContact O-CB 3.08Å; L175-V179 WeakPolarHBondContact O-CG2 3.18Å; L175-V179 PolarHBondContact O-N 3.45Å; V179-F181 VanDerWaalsContact C-N 3.28Å; V179-F181 PolarHBondContact O-N 2.87Å; V179-L182 PolarHBondContact O-N 3.33Å; V179-Q183 HydrophobicContact CG1-CG 4.3Å; V179-Q183 VanDerWaalsContact O-CB 3.31Å; V179-Q183 WeakPolarHBondContact O-CB 3.48Å; V179-Q183 VanDerWaalsContact O-CG 3.23Å; V179-Q183 WeakPolarHBondContact O-CG 3.18Å; V179-Q183 PolarHBondContact O-N 2.85Å
180P93.9Very high93.4Very high9 Ų934.7 Ų34.76%0.05816%0.164CC..Hα-helixtrans-62.1-36.4177.7-2335.9000112.7C176 K184 E238 F242C176-P180 WeakPolarHBondContact O-CD 3.37Å; C176-P180 VanDerWaalsContact O-CG 3.24Å; C176-P180 WeakPolarHBondContact O-CG 3.43Å; P180-K184 WeakPolarHBondContact O-CG 3.47Å; P180-K184 PolarHBondContact O-N 3.11Å; P180-E238 HydrophobicContact CB-CB 4.13Å; P180-F242 HydrophobicContact CB-CD1 4.33Å; P180-F242 HydrophobicContact CB-CD2 4.11Å; P180-F242 HydrophobicContact CB-CE1 4.35Å; P180-F242 HydrophobicContact CB-CE2 4.17Å; P180-F242 HydrophobicContact CB-CG 4.19Å; P180-F242 HydrophobicContact CB-CZ 4.26Å; P180-F242 HydrophobicContact CG-CB 4.4Å; P180-F242 HydrophobicContact CG-CD1 3.65Å; P180-F242 HydrophobicContact CG-CD2 4.25Å; P180-F242 HydrophobicContact CG-CE1 3.88Å; P180-F242 HydrophobicContact CG-CE2 4.49Å; P180-F242 HydrophobicContact CG-CG 3.82Å; P180-F242 HydrophobicContact CG-CZ 4.3Å
181F96.2Very high93.7Very high38 Ų3825 Ų2517%0.16713%0.127CC..Hα-helixtrans-60.4-55.4174.8171-102.5000111.8K177 L178 V179 Q183 K184 A185 L232 A235 V236 A239K177-F181 WeakPolarHBondContact O-CB 3.36Å; K177-F181 PolarHBondContact O-N 3.43Å; L178-F181 HydrophobicContact CD1-CD1 4.38Å; L178-F181 PolarHBondContact O-N 3.39Å; V179-F181 VanDerWaalsContact C-N 3.28Å; V179-F181 PolarHBondContact O-N 2.87Å; F181-Q183 VanDerWaalsContact C-N 3.33Å; F181-Q183 PolarHBondContact O-N 3.45Å; F181-K184 PolarHBondContact O-N 3.3Å; F181-A185 WeakPolarHBondContact O-CB 3.45Å; F181-A185 PolarHBondContact O-N 2.88Å; F181-L232 HydrophobicContact CE1-CD2 4.09Å; F181-L232 WeakPolarHBondContact CE2-O 3.41Å; F181-L232 HydrophobicContact CZ-CB 4.5Å; F181-L232 HydrophobicContact CZ-CD2 3.69Å; F181-A235 HydrophobicContact CD2-CB 3.69Å; F181-A235 WeakPolarHBondContact CD2-O 3.32Å; F181-A235 HydrophobicContact CE2-CB 3.83Å; F181-A235 WeakPolarHBondContact O-CB 3.32Å; F181-V236 HydrophobicContact CE2-CG2 4.36Å; F181-A239 HydrophobicContact CB-CB 4.06Å; F181-A239 HydrophobicContact CD2-CB 4.22Å; F181-A239 HydrophobicContact CG-CB 4.33Å
182L95.6Very high94Very high38 Ų3822 Ų2220%0.19912%0.115CC..Hα-helixtrans-67.1-35.4-179.2-69.7178.4000111.8I146 I150 L178 V179 A185 S186I146-L182 HydrophobicContact CG2-CB 4.47Å; I150-L182 HydrophobicContact CD1-CB 3.68Å; I150-L182 HydrophobicContact CD1-CD1 3.27Å; I150-L182 HydrophobicContact CD1-CG 4.07Å; L178-L182 HydrophobicContact CD1-CD1 3.68Å; L178-L182 HydrophobicContact CD1-CG 3.94Å; L178-L182 HydrophobicContact CD2-CD1 4.25Å; L178-L182 HydrophobicContact CG-CD1 3.71Å; L178-L182 HydrophobicContact CG-CG 4.24Å; L178-L182 WeakPolarHBondContact O-CB 3.18Å; L178-L182 WeakPolarHBondContact O-CG 3.42Å; L178-L182 PolarHBondContact O-N 3.49Å; V179-L182 PolarHBondContact O-N 3.33Å; L182-A185 PolarHBondContact O-N 2.92Å; L182-S186 WeakPolarHBondContact O-CB 3.38Å; L182-S186 PolarHBondContact O-N 2.95Å; L182-S186 PolarHBondContact O-OG 3.31Å
183Q94.4Very high94.2Very high36 Ų3622 Ų2217%0.16812%0.115CC..Hα-helixtrans-55.8-54.6170.6-78.6169.9-1300110.7Y147 D151 V179 F181 A185 S186 V187Y147-Q183 HydrophobicContact CE2-CB 4.18Å; Y147-Q183 HydrophobicContact CE2-CG 4.2Å; D151-Q183 HydrophobicContact CB-CG 4.3Å; D151-Q183 PolarHBondContact OD1-NE2 2.95Å; V179-Q183 HydrophobicContact CG1-CG 4.3Å; V179-Q183 VanDerWaalsContact O-CB 3.31Å; V179-Q183 WeakPolarHBondContact O-CB 3.48Å; V179-Q183 VanDerWaalsContact O-CG 3.23Å; V179-Q183 WeakPolarHBondContact O-CG 3.18Å; V179-Q183 PolarHBondContact O-N 2.85Å; F181-Q183 VanDerWaalsContact C-N 3.33Å; F181-Q183 PolarHBondContact O-N 3.45Å; Q183-A185 PolarHBondContact O-N 3.3Å; Q183-S186 PolarHBondContact O-N 3.03Å; Q183-V187 WeakPolarHBondContact O-CG2 3.26Å; Q183-V187 PolarHBondContact O-N 3.44Å; Q183-V187 VanDerWaalsContact O-N 3.08Å
184K94.5Very high94.1Very high17 Ų1719.2 Ų19.27%0.07410%0.1CC..Hα-helixtrans-69.1-34.6-178.8-67.1-43-176.3178.40113.7P180 F181 V187 G188 A235 E238 L277 Y281 R344P180-K184 WeakPolarHBondContact O-CG 3.47Å; P180-K184 PolarHBondContact O-N 3.11Å; F181-K184 PolarHBondContact O-N 3.3Å; K184-V187 PolarHBondContact O-N 3.06Å; K184-G188 PolarHBondContact O-N 3.46Å; K184-A235 HydrophobicContact CB-CB 3.9Å; K184-E238 HydrophobicContact CB-CG 4.09Å; K184-E238 VanDerWaalsContact CE-OE1 3.22Å; K184-E238 WeakPolarHBondContact CE-OE1 3.37Å; K184-E238 HydrophobicContact CG-CG 3.48Å; K184-E238 VanDerWaalsContact CG-CG 3.48Å; K184-E238 WeakPolarHBondContact CG-OE1 3.32Å; K184-L277 HydrophobicContact CD-CD2 4.09Å; K184-Y281 WeakPolarHBondContact O-CE1 3.45Å; K184-R344 VanDerWaalsContact NZ-NH1 3.2Å
185A96.7Very high94Very high2 Ų217.3 Ų17.32%0.0179%0.087CC..Hα-helixtrans-61.9-49.4174.700000110.4F181 L182 Q183 V187 G188 I189 S231 L232 A235F181-A185 WeakPolarHBondContact O-CB 3.45Å; F181-A185 PolarHBondContact O-N 2.88Å; L182-A185 PolarHBondContact O-N 2.92Å; Q183-A185 PolarHBondContact O-N 3.3Å; A185-V187 PolarHBondContact O-N 3.38Å; A185-G188 WeakPolarHBondContact O-CA 3.4Å; A185-G188 PolarHBondContact O-N 3.01Å; A185-G188 VanDerWaalsContact O-N 3.09Å; A185-I189 WeakPolarHBondContact O-CG1 3.48Å; A185-I189 PolarHBondContact O-N 3.32Å; A185-S231 WeakPolarHBondContact O-CB 3.37Å; A185-L232 HydrophobicContact CB-CD2 3.92Å; A185-A235 HydrophobicContact CB-CB 3.89Å
186S95.9Very high94Very high2 Ų216.5 Ų16.51%0.0148%0.084CC..Hα-helixtrans-61-42177.9-71.30000112.7G143 I146 Y147 L182 Q183 G188 I189 T190G143-S186 WeakPolarHBondContact O-CB 3.42Å; G143-S186 PolarHBondContact O-OG 3.4Å; G143-S186 VanDerWaalsContact O-OG 3.1Å; I146-S186 WeakPolarHBondContact CG2-OG 3.49Å; Y147-S186 PolarHBondContact N-OG 2.83Å; L182-S186 WeakPolarHBondContact O-CB 3.38Å; L182-S186 PolarHBondContact O-N 2.95Å; L182-S186 PolarHBondContact O-OG 3.31Å; Q183-S186 PolarHBondContact O-N 3.03Å; S186-G188 VanDerWaalsContact C-N 3.25Å; S186-G188 PolarHBondContact O-N 3.45Å; S186-I189 WeakPolarHBondContact O-CB 3.4Å; S186-I189 PolarHBondContact O-N 3.35Å; S186-I189 VanDerWaalsContact O-N 3.16Å; S186-T190 PolarHBondContact O-N 3.25Å; S186-T190 PolarHBondContact O-OG1 3.21Å; S186-T190 VanDerWaalsContact O-OG1 3.13Å
187V93.9Very high93.6Very high4 Ų417 Ų172%0.0249%0.086CC..Hα-helixtrans-63.6-36.3176.4-177.40000111Y147 Q183 K184 A185 T190 V191 Y281 W337Y147-V187 HydrophobicContact CD2-CG2 4.02Å; Y147-V187 HydrophobicContact CE2-CG2 3.65Å; Q183-V187 WeakPolarHBondContact O-CG2 3.26Å; Q183-V187 PolarHBondContact O-N 3.44Å; Q183-V187 VanDerWaalsContact O-N 3.08Å; K184-V187 PolarHBondContact O-N 3.06Å; A185-V187 PolarHBondContact O-N 3.38Å; V187-T190 PolarHBondContact O-N 2.84Å; V187-V191 HydrophobicContact CG1-CG2 4.38Å; V187-V191 WeakPolarHBondContact O-CB 3.41Å; V187-V191 VanDerWaalsContact O-CG2 3.3Å; V187-V191 WeakPolarHBondContact O-CG2 3.49Å; V187-V191 PolarHBondContact O-N 3.29Å; V187-Y281 HydrophobicContact CB-CD1 4.18Å; V187-Y281 HydrophobicContact CB-CE1 4.36Å; V187-Y281 HydrophobicContact CG1-CD1 3.69Å; V187-Y281 HydrophobicContact CG1-CE1 4.36Å; V187-Y281 HydrophobicContact CG1-CG 4.43Å; V187-W337 HydrophobicContact CB-CH2 4Å; V187-W337 HydrophobicContact CB-CZ2 4.41Å; V187-W337 HydrophobicContact CG1-CE3 4.37Å; V187-W337 HydrophobicContact CG1-CH2 3.46Å; V187-W337 VanDerWaalsContact CG1-CH2 3.46Å; V187-W337 HydrophobicContact CG1-CZ2 3.79Å; V187-W337 HydrophobicContact CG1-CZ3 3.73Å; V187-W337 HydrophobicContact CG2-CH2 3.16Å; V187-W337 HydrophobicContact CG2-CZ2 3.72Å; V187-W337 HydrophobicContact CG2-CZ3 4.01Å
188G95.6Very high93.1Very high0 Ų014.3 Ų14.30%08%0.076CC..Hα-helixtrans-62.4-45.417400000111.5K184 A185 S186 T190 V191 L192 S231 Y281K184-G188 PolarHBondContact O-N 3.46Å; A185-G188 WeakPolarHBondContact O-CA 3.4Å; A185-G188 PolarHBondContact O-N 3.01Å; A185-G188 VanDerWaalsContact O-N 3.09Å; S186-G188 VanDerWaalsContact C-N 3.25Å; S186-G188 PolarHBondContact O-N 3.45Å; G188-T190 VanDerWaalsContact C-N 3.31Å; G188-T190 PolarHBondContact O-N 3.46Å; G188-V191 PolarHBondContact O-N 2.86Å; G188-L192 WeakPolarHBondContact O-CB 3.47Å; G188-L192 WeakPolarHBondContact O-CG 3.32Å; G188-L192 PolarHBondContact O-N 2.88Å; G188-S231 PolarHBondContact O-OG 3.22Å; G188-Y281 VanDerWaalsContact CA-CE1 3.46Å
189I95.8Very high92.8Very high3 Ų312.7 Ų12.72%0.0157%0.069CC..Hα-helixtrans-59-46.3176.6-66.9166.3000109.4A185 S186 N193 I227 W228 S231A185-I189 WeakPolarHBondContact O-CG1 3.48Å; A185-I189 PolarHBondContact O-N 3.32Å; S186-I189 WeakPolarHBondContact O-CB 3.4Å; S186-I189 PolarHBondContact O-N 3.35Å; S186-I189 VanDerWaalsContact O-N 3.16Å; I189-N193 VanDerWaalsContact CG2-ND2 3.31Å; I189-N193 WeakPolarHBondContact CG2-ND2 3.3Å; I189-N193 VanDerWaalsContact O-CB 3.23Å; I189-N193 WeakPolarHBondContact O-CB 3.29Å; I189-N193 PolarHBondContact O-N 2.96Å; I189-N193 PolarHBondContact O-ND2 2.9Å; I189-I227 HydrophobicContact CG2-CG2 4.46Å; I189-W228 HydrophobicContact CD1-CD2 3.8Å; I189-W228 HydrophobicContact CD1-CE3 3.73Å; I189-W228 HydrophobicContact CD1-CG 4.47Å; I189-W228 HydrophobicContact CD1-CH2 3.93Å; I189-W228 HydrophobicContact CD1-CZ2 3.97Å; I189-W228 HydrophobicContact CD1-CZ3 3.81Å; I189-W228 HydrophobicContact CG1-CD2 4.4Å; I189-S231 WeakPolarHBondContact CA-OG 3.19Å; I189-S231 PolarHBondContact N-OG 3.48Å
190T93.1Very high92.3Very high4 Ų413.2 Ų13.23%0.0257%0.071CC..Hα-helixtrans-60.4-52178.5-60.10000111.6L140 D144 S186 V187 G188 N193 L194L140-T190 HydrophobicContact CD1-CG2 3.78Å; D144-T190 PolarHBondContact OD1-OG1 3.11Å; S186-T190 PolarHBondContact O-N 3.25Å; S186-T190 PolarHBondContact O-OG1 3.21Å; S186-T190 VanDerWaalsContact O-OG1 3.13Å; V187-T190 PolarHBondContact O-N 2.84Å; G188-T190 VanDerWaalsContact C-N 3.31Å; G188-T190 PolarHBondContact O-N 3.46Å; T190-N193 PolarHBondContact O-N 3.31Å; T190-L194 HydrophobicContact CG2-CD1 4.32Å; T190-L194 WeakPolarHBondContact O-CG 3.43Å; T190-L194 PolarHBondContact O-N 3.35Å
191V93.5Very high91.6Very high0 Ų015.1 Ų15.10%08%0.077CC..Hα-helixtrans-62.7-47.2-177.1164.40000111.9V187 G188 L194 C195 Y281 P285 F333V187-V191 HydrophobicContact CG1-CG2 4.38Å; V187-V191 WeakPolarHBondContact O-CB 3.41Å; V187-V191 VanDerWaalsContact O-CG2 3.3Å; V187-V191 WeakPolarHBondContact O-CG2 3.49Å; V187-V191 PolarHBondContact O-N 3.29Å; G188-V191 PolarHBondContact O-N 2.86Å; V191-L194 PolarHBondContact O-N 3.49Å; V191-C195 PolarHBondContact O-N 3.1Å; V191-C195 VanDerWaalsContact O-N 3.07Å; V191-C195 PolarHBondContact O-SG 2.89Å; V191-C195 VanDerWaalsContact O-SG 3.42Å; V191-Y281 HydrophobicContact CG2-CD1 4.47Å; V191-Y281 VanDerWaalsContact CG2-O 3.23Å; V191-Y281 WeakPolarHBondContact CG2-O 3.36Å; V191-P285 HydrophobicContact CB-CG 4.46Å; V191-P285 HydrophobicContact CG1-CB 3.92Å; V191-P285 HydrophobicContact CG1-CG 3.63Å; V191-P285 HydrophobicContact CG2-CG 4.21Å; V191-F333 HydrophobicContact CG2-CE2 3.79Å; V191-F333 HydrophobicContact CG2-CZ 3.58Å
192L94.8Very high90.8Very high26 Ų2616.1 Ų16.114%0.1368%0.081CC..Hα-helixtrans-69.9-34.7-179.7-67.9175.3000111.9G188 C195 A196 I227 L230 F280G188-L192 WeakPolarHBondContact O-CB 3.47Å; G188-L192 WeakPolarHBondContact O-CG 3.32Å; G188-L192 PolarHBondContact O-N 2.88Å; L192-C195 WeakPolarHBondContact O-CB 3.18Å; L192-C195 PolarHBondContact O-N 3.42Å; L192-A196 WeakPolarHBondContact O-CB 3.49Å; L192-A196 PolarHBondContact O-N 3.46Å; L192-I227 HydrophobicContact CB-CB 4.39Å; L192-I227 HydrophobicContact CB-CG1 4.04Å; L192-I227 HydrophobicContact CB-CG2 3.77Å; L192-I227 HydrophobicContact CD1-CG2 4.34Å; L192-L230 HydrophobicContact CD1-CB 4.19Å; L192-L230 HydrophobicContact CD1-CD2 3.82Å; L192-L230 HydrophobicContact CD1-CG 4.06Å; L192-L230 HydrophobicContact CD2-CD2 4.37Å; L192-F280 HydrophobicContact CD2-CZ 4.2Å
193N92.7Very high90Very high0 Ų018.8 Ų18.80%09%0.088CC..Hα-helixtrans-65.7-38171.7-85.9-68.3000112.1L136 S139 L140 I189 T190 C195 A196 L197L136-N193 PolarHBondContact O-OD1 3.27Å; S139-N193 PolarHBondContact OG-ND2 3.3Å; L140-N193 HydrophobicContact CB-CB 4.24Å; L140-N193 HydrophobicContact CD1-CB 4.37Å; I189-N193 VanDerWaalsContact CG2-ND2 3.31Å; I189-N193 WeakPolarHBondContact CG2-ND2 3.3Å; I189-N193 VanDerWaalsContact O-CB 3.23Å; I189-N193 WeakPolarHBondContact O-CB 3.29Å; I189-N193 PolarHBondContact O-N 2.96Å; I189-N193 PolarHBondContact O-ND2 2.9Å; T190-N193 PolarHBondContact O-N 3.31Å; N193-C195 VanDerWaalsContact C-N 3.35Å; N193-A196 PolarHBondContact O-N 3.4Å; N193-L197 WeakPolarHBondContact O-CB 3.3Å; N193-L197 VanDerWaalsContact O-CG 3.24Å; N193-L197 WeakPolarHBondContact O-CG 3.36Å; N193-L197 PolarHBondContact O-N 2.93Å
194L88.8Confident89Confident4 Ų418.4 Ų18.42%0.0219%0.091CC..Hα-helixtrans-62.5-42.9174.6-72.5174.6000111.4T190 V191 L197 S198 L329 F333T190-L194 HydrophobicContact CG2-CD1 4.32Å; T190-L194 WeakPolarHBondContact O-CG 3.43Å; T190-L194 PolarHBondContact O-N 3.35Å; V191-L194 PolarHBondContact O-N 3.49Å; L194-L197 PolarHBondContact O-N 3.29Å; L194-S198 PolarHBondContact O-N 3.34Å; L194-S198 PolarHBondContact O-OG 2.74Å; L194-L329 HydrophobicContact CD2-CB 4.45Å; L194-F333 HydrophobicContact CD1-CB 4.13Å; L194-F333 HydrophobicContact CD1-CD2 3.84Å; L194-F333 HydrophobicContact CD1-CE2 4.49Å; L194-F333 HydrophobicContact CD1-CG 3.95Å
195C91.8Very high87.7Confident14 Ų1418 Ų1810%0.0959%0.09CC..Hα-helixtrans-59.1-49.7172.4-69.90000111.8V191 L192 N193 L197 S198 V199 C288V191-C195 PolarHBondContact O-N 3.1Å; V191-C195 VanDerWaalsContact O-N 3.07Å; V191-C195 PolarHBondContact O-SG 2.89Å; V191-C195 VanDerWaalsContact O-SG 3.42Å; L192-C195 WeakPolarHBondContact O-CB 3.18Å; L192-C195 PolarHBondContact O-N 3.42Å; N193-C195 VanDerWaalsContact C-N 3.35Å; C195-L197 VanDerWaalsContact C-N 3.34Å; C195-L197 PolarHBondContact O-N 3.31Å; C195-S198 WeakPolarHBondContact O-CB 3.44Å; C195-S198 PolarHBondContact O-N 3.18Å; C195-V199 WeakPolarHBondContact O-CG2 3.23Å; C195-V199 PolarHBondContact O-N 3.38Å; C195-C288 VanDerWaalsContact SG-SG 3.66Å
196A90.7Very high86.5Confident7 Ų719.6 Ų19.66%0.05810%0.103CC..Hα-helixtrans-59.4-42.4178.600000112.3L136 L192 N193 S198 V199 D200 E223 I227L136-A196 HydrophobicContact CD1-CB 4.17Å; L136-A196 HydrophobicContact CD2-CB 4.17Å; L192-A196 WeakPolarHBondContact O-CB 3.49Å; L192-A196 PolarHBondContact O-N 3.46Å; N193-A196 PolarHBondContact O-N 3.4Å; A196-S198 PolarHBondContact O-N 3.15Å; A196-V199 PolarHBondContact O-N 3.14Å; A196-D200 WeakPolarHBondContact O-CB 3.46Å; A196-D200 PolarHBondContact O-N 3.05Å; A196-E223 VanDerWaalsContact CB-OE1 3.28Å; A196-E223 WeakPolarHBondContact CB-OE1 3.32Å; A196-I227 HydrophobicContact CB-CD1 3.99Å
197L85.8Confident85.2Confident9 Ų922 Ų225%0.04712%0.12CC..Hα-helixtrans-63.1-41.7175.5-74.6168.9000111.6L136 I137 L140 N193 L194 C195 D200 R201L136-L197 HydrophobicContact CB-CD2 3.9Å; L136-L197 HydrophobicContact CB-CG 4.31Å; L136-L197 HydrophobicContact CD1-CD2 4.17Å; I137-L197 HydrophobicContact CG1-CD2 4.24Å; L140-L197 HydrophobicContact CD2-CD1 4.5Å; N193-L197 WeakPolarHBondContact O-CB 3.3Å; N193-L197 VanDerWaalsContact O-CG 3.24Å; N193-L197 WeakPolarHBondContact O-CG 3.36Å; N193-L197 PolarHBondContact O-N 2.93Å; L194-L197 PolarHBondContact O-N 3.29Å; C195-L197 VanDerWaalsContact C-N 3.34Å; C195-L197 PolarHBondContact O-N 3.31Å; L197-D200 PolarHBondContact O-N 2.92Å; L197-R201 WeakPolarHBondContact O-CG 3.28Å; L197-R201 PolarHBondContact O-N 3.4Å
198S84.8Confident83.2Confident7 Ų727.9 Ų27.95%0.04914%0.142CC..Hα-helixtrans-61.2-43.6174.7-68.60000112L194 C195 A196 R201 Y202 T289 V326L194-S198 PolarHBondContact O-N 3.34Å; L194-S198 PolarHBondContact O-OG 2.74Å; C195-S198 WeakPolarHBondContact O-CB 3.44Å; C195-S198 PolarHBondContact O-N 3.18Å; A196-S198 PolarHBondContact O-N 3.15Å; S198-R201 PolarHBondContact O-N 3.22Å; S198-Y202 PolarHBondContact O-N 3.07Å; S198-T289 PolarHBondContact OG-OG1 3.22Å; S198-V326 WeakPolarHBondContact OG-CG1 3.3Å
199V86.4Confident80.9Confident41 Ų4132.7 Ų32.725%0.24818%0.176CC..Hα-helixtrans-62.6-46.9175.1175.10000111.1C195 A196 R201 Y202 R203 F292C195-V199 WeakPolarHBondContact O-CG2 3.23Å; C195-V199 PolarHBondContact O-N 3.38Å; A196-V199 PolarHBondContact O-N 3.14Å; V199-R201 VanDerWaalsContact C-N 3.3Å; V199-R201 PolarHBondContact O-N 3.12Å; V199-Y202 PolarHBondContact O-N 3.09Å; V199-R203 HydrophobicContact CG1-CG 4.24Å; V199-R203 WeakPolarHBondContact O-CB 3.23Å; V199-R203 VanDerWaalsContact O-CG 3.31Å; V199-R203 WeakPolarHBondContact O-CG 3.42Å; V199-R203 PolarHBondContact O-N 3.11Å; V199-F292 HydrophobicContact CG2-CD2 3.83Å; V199-F292 HydrophobicContact CG2-CE1 4.16Å; V199-F292 HydrophobicContact CG2-CE2 3.33Å; V199-F292 HydrophobicContact CG2-CG 4.47Å; V199-F292 HydrophobicContact CG2-CZ 3.53Å
200D82.6Confident79Confident16 Ų1637.4 Ų37.49%0.08619%0.193CC..Hα-helixtrans-58-42.9178.117774.5000111.4P133 A196 L197 R203 A204P133-D200 VanDerWaalsContact CG-OD2 3.32Å; P133-D200 WeakPolarHBondContact CG-OD2 3.3Å; A196-D200 WeakPolarHBondContact O-CB 3.46Å; A196-D200 PolarHBondContact O-N 3.05Å; L197-D200 PolarHBondContact O-N 2.92Å; D200-R203 PolarHBondContact O-N 3.41Å; D200-A204 WeakPolarHBondContact O-CB 3.44Å; D200-A204 PolarHBondContact O-N 2.97Å
201R79.3Confident76.9Confident49 Ų4943.7 Ų43.719%0.18523%0.231CC..Hα-helixtrans-66.8-42.8177.5-63.7-39.8163.2-172.5-9.3113P133 L197 S198 V199 A204 V205 V322 V326P133-R201 VanDerWaalsContact CB-NH2 3.3Å; L197-R201 WeakPolarHBondContact O-CG 3.28Å; L197-R201 PolarHBondContact O-N 3.4Å; S198-R201 PolarHBondContact O-N 3.22Å; V199-R201 VanDerWaalsContact C-N 3.3Å; V199-R201 PolarHBondContact O-N 3.12Å; R201-A204 PolarHBondContact O-N 2.97Å; R201-V205 VanDerWaalsContact O-CG2 3.27Å; R201-V205 WeakPolarHBondContact O-CG2 3.29Å; R201-V205 PolarHBondContact O-N 3.08Å; R201-V322 HydrophobicContact CG-CG1 4.47Å; R201-V326 HydrophobicContact CG-CG2 3.78Å
202Y79.6Confident75Confident59 Ų5950.1 Ų50.123%0.23126%0.261CS..Hα-helixtrans-58.9-49.5173.3168.8-108.8000111S198 V199 A204 V205 A206 F292 L295 M296S198-Y202 PolarHBondContact O-N 3.07Å; V199-Y202 PolarHBondContact O-N 3.09Å; Y202-A204 VanDerWaalsContact C-N 3.33Å; Y202-A204 PolarHBondContact O-N 3.37Å; Y202-V205 PolarHBondContact O-N 3.5Å; Y202-A206 HydrophobicContact CE1-CB 4.46Å; Y202-A206 HydrophobicContact CE2-CB 4.12Å; Y202-A206 PolarHBondContact O-N 3.13Å; Y202-F292 AromaticContact CD1-CD1 3.69Å; Y202-F292 HydrophobicContact CD1-CD1 3.69Å; Y202-F292 AromaticContact CD1-CE1 3.94Å; Y202-F292 HydrophobicContact CD1-CE1 3.94Å; Y202-F292 HydrophobicContact CE1-CD1 4.48Å; Y202-F292 HydrophobicContact CE1-CE1 4.5Å; Y202-F292 AromaticContact CG-CD1 3.75Å; Y202-F292 HydrophobicContact CG-CD1 3.75Å; Y202-F292 HydrophobicContact CG-CE1 4.46Å; Y202-L295 HydrophobicContact CD2-CB 3.87Å; Y202-L295 HydrophobicContact CE2-CB 3.56Å; Y202-L295 HydrophobicContact CE2-CD1 4.49Å; Y202-M296 HydrophobicContact CD2-CB 4.26Å
203R79.1Confident73.1Confident94 Ų9451.1 Ų51.136%0.35528%0.278SS..Hα-helixtrans-61.6-38.7179.7-71.9178.667.6-106.4-1.7112.8V199 D200 V205 S207V199-R203 HydrophobicContact CG1-CG 4.24Å; V199-R203 WeakPolarHBondContact O-CB 3.23Å; V199-R203 VanDerWaalsContact O-CG 3.31Å; V199-R203 WeakPolarHBondContact O-CG 3.42Å; V199-R203 PolarHBondContact O-N 3.11Å; D200-R203 PolarHBondContact O-N 3.41Å; R203-V205 PolarHBondContact O-N 2.99Å; R203-S207 WeakPolarHBondContact O-CA 3.33Å; R203-S207 WeakPolarHBondContact O-CB 3.4Å; R203-S207 PolarHBondContact O-N 2.83Å
204A73.5Confident71.4Confident28 Ų2857.3 Ų57.323%0.23132%0.315CS..Hα-helixtrans-65.6-23.4176.500000113D200 R201 Y202 R319D200-A204 WeakPolarHBondContact O-CB 3.44Å; D200-A204 PolarHBondContact O-N 2.97Å; R201-A204 PolarHBondContact O-N 2.97Å; Y202-A204 VanDerWaalsContact C-N 3.33Å; Y202-A204 PolarHBondContact O-N 3.37Å; A204-R319 VanDerWaalsContact O-CZ 3.24Å; A204-R319 PolarHBondContact O-NH1 3.47Å
205V68.4Low70.4Confident9 Ų958.8 Ų58.86%0.05533%0.332CS..Hα-helixtrans-90-45.4178.7174.70000111R201 Y202 R203 M296 M300 R319R201-V205 VanDerWaalsContact O-CG2 3.27Å; R201-V205 WeakPolarHBondContact O-CG2 3.29Å; R201-V205 PolarHBondContact O-N 3.08Å; Y202-V205 PolarHBondContact O-N 3.5Å; R203-V205 PolarHBondContact O-N 2.99Å; V205-M296 HydrophobicContact CB-CE 4.42Å; V205-M296 HydrophobicContact CB-CG 4.19Å; V205-M296 HydrophobicContact CG1-CE 4.44Å; V205-M296 HydrophobicContact CG1-CG 4.05Å; V205-M296 HydrophobicContact CG2-CE 3.4Å; V205-M296 VanDerWaalsContact CG2-CE 3.4Å; V205-M296 HydrophobicContact CG2-CG 4.06Å; V205-M296 HydrophobicContact CG2-SD 3.83Å; V205-M300 HydrophobicContact CG1-CG 3.84Å; V205-M300 HydrophobicContact CG1-SD 4.46Å; V205-R319 HydrophobicContact CG2-CB 4.28Å
206A71.3Confident69.8Low36 Ų3662.1 Ų62.130%0.29835%0.348SS..Hα-helixtrans-72.3-38.9179.600000112.7Y202 W208Y202-A206 HydrophobicContact CE1-CB 4.46Å; Y202-A206 HydrophobicContact CE2-CB 4.12Å; Y202-A206 PolarHBondContact O-N 3.13Å; A206-W208 PolarHBondContact O-N 2.94Å
207S66.9Low69.5Low51 Ų5164 Ų6436%0.35736%0.359SS..  trans-92.4101.7177.2-172.60000110.2R203 S209R203-S207 WeakPolarHBondContact O-CA 3.33Å; R203-S207 WeakPolarHBondContact O-CB 3.4Å; R203-S207 PolarHBondContact O-N 2.83Å; S207-S209 VanDerWaalsContact C-N 3.28Å; S207-S209 PolarHBondContact O-N 3.46Å
208W53.1Low69.6Low128 Ų12869.9 Ų69.949%0.48539%0.39SS..THydrogen-bonded Turntrans-71.2-15.7178.7-94.265.6000114.8A206 L308 L312A206-W208 PolarHBondContact O-N 2.94Å; W208-L308 HydrophobicContact CH2-CD2 4.39Å; W208-L312 HydrophobicContact CH2-CD1 3.14Å; W208-L312 HydrophobicContact CH2-CD2 3.58Å; W208-L312 HydrophobicContact CH2-CG 3.9Å; W208-L312 HydrophobicContact CZ2-CD1 3.31Å; W208-L312 HydrophobicContact CZ2-CD2 3.62Å; W208-L312 HydrophobicContact CZ2-CG 4.05Å; W208-L312 HydrophobicContact CZ3-CD1 4.09Å
209S47.8Very low69.7Low102 Ų10274.5 Ų74.571%0.71341%0.414SS*.THydrogen-bonded Turntrans-1086.5-169.474.90000116S207 V211S207-S209 VanDerWaalsContact C-N 3.28Å; S207-S209 PolarHBondContact O-N 3.46Å; S209-V211 PolarHBondContact O-N 3.36Å
210R54.7Low69.8Low102 Ų10272.9 Ų72.939%0.38540%0.404SS..  trans-74.793.2179.8-150.7178.8-166.8-163.43.2110Q212R210-Q212 PolarHBondContact O-N 3.05Å
211V49.3Very low70.1Confident135 Ų13575.2 Ų75.282%0.81842%0.419SS*.  trans-54.9107.7166.8-179.90000107.2S209 G213S209-V211 PolarHBondContact O-N 3.36Å; V211-G213 PolarHBondContact O-N 2.94Å
212Q53.6Low70.8Confident136 Ų13677.1 Ų77.164%0.63643%0.431SS*.  trans-73.879.1175.5-112.4154.9-10.300108.1R210R210-Q212 PolarHBondContact O-N 3.05Å
213G54.4Low71.4Confident47 Ų4777.2 Ų77.249%0.48543%0.434SS..  trans-59.9152.317100000111.2V211 G215V211-G213 PolarHBondContact O-N 2.94Å; G213-G215 PolarHBondContact O-N 3.4Å
214V58.1Low72.2Confident130 Ų13074.2 Ų74.279%0.78843%0.425SS*.SBendtrans-70.7118.4170.9179.40000107.8
215G67.3Low73.3Confident35 Ų3576.9 Ų76.936%0.36144%0.438SS..BIsolated β-bridgetrans141.2160.4-178.300000113.1R130 G213 P217R130-G215 CarbonylContact O-C 3.52Å; R130-G215 PolarHBondContact O-N 3.08Å; G213-G215 PolarHBondContact O-N 3.4Å; G215-P217 WeakPolarHBondContact O-CD 3.36Å
216I79.3Confident74.6Confident84 Ų8480.3 Ų80.343%0.43146%0.459SS..  trans-91.4115.4173.6-56.6174000106.9A135 T220 V221A135-I216 HydrophobicContact CB-CD1 4.04Å; A135-I216 HydrophobicContact CB-CG1 4.28Å; A135-I216 HydrophobicContact CB-CG2 4.15Å; I216-T220 HydrophobicContact CG2-CG2 4.33Å; I216-V221 HydrophobicContact CG2-CG2 3.71Å
217P84.4Confident75.8Confident47 Ų4779.1 Ų79.131%0.30545%0.447SS..  trans-60.2141.1175.6-20.232.1000110.3G215 L219 T220 V221G215-P217 WeakPolarHBondContact O-CD 3.36Å; P217-L219 PolarHBondContact O-N 2.9Å; P217-L219 VanDerWaalsContact O-N 3.13Å; P217-T220 WeakPolarHBondContact O-CB 3.45Å; P217-T220 PolarHBondContact O-N 3.26Å; P217-V221 PolarHBondContact O-N 3.34Å
218L87.1Confident77.3Confident132 Ų13279.8 Ų79.869%0.69144%0.442SS*.Hα-helixtrans-52.3-37.6175179.763.2000111.6T220 V221 I222L218-T220 VanDerWaalsContact C-N 3.29Å; L218-T220 PolarHBondContact O-N 3.4Å; L218-V221 WeakPolarHBondContact O-CB 3.33Å; L218-V221 PolarHBondContact O-N 3.28Å; L218-V221 VanDerWaalsContact O-N 3.08Å; L218-I222 HydrophobicContact CG-CD1 4.04Å; L218-I222 HydrophobicContact CG-CG1 4.49Å; L218-I222 WeakPolarHBondContact O-CG1 3.35Å; L218-I222 PolarHBondContact O-N 3.01Å
219L86.8Confident79.4Confident104 Ų10477.3 Ų77.355%0.54544%0.441SS..Hα-helixtrans-57.8-38.9175.8-170.767.1000112.9P217 I222 E223P217-L219 PolarHBondContact O-N 2.9Å; P217-L219 VanDerWaalsContact O-N 3.13Å; L219-I222 PolarHBondContact O-N 2.85Å; L219-E223 WeakPolarHBondContact O-CB 3.44Å; L219-E223 PolarHBondContact O-N 3.25Å
220T88.5Confident81.8Confident6 Ų675.7 Ų75.74%0.03742%0.424CS..Hα-helixtrans-71-33.2177-59.50000111.7A135 L136 I216 P217 L218 E223 I224A135-T220 HydrophobicContact CB-CG2 4.29Å; L136-T220 HydrophobicContact CG-CG2 4.27Å; I216-T220 HydrophobicContact CG2-CG2 4.33Å; P217-T220 WeakPolarHBondContact O-CB 3.45Å; P217-T220 PolarHBondContact O-N 3.26Å; L218-T220 VanDerWaalsContact C-N 3.29Å; L218-T220 PolarHBondContact O-N 3.4Å; T220-E223 PolarHBondContact O-N 2.86Å; T220-I224 HydrophobicContact CG2-CD1 4.1Å; T220-I224 VanDerWaalsContact O-CG1 3.3Å; T220-I224 WeakPolarHBondContact O-CG1 3.48Å; T220-I224 PolarHBondContact O-N 3.48Å
221V90.8Very high83.8Confident66 Ų6670.9 Ų70.940%0.441%0.406SS..Hα-helixtrans-65.1-46.2173.3-179.20000110.3I216 P217 L218 E223 I224 V225I216-V221 HydrophobicContact CG2-CG2 3.71Å; P217-V221 PolarHBondContact O-N 3.34Å; L218-V221 WeakPolarHBondContact O-CB 3.33Å; L218-V221 PolarHBondContact O-N 3.28Å; L218-V221 VanDerWaalsContact O-N 3.08Å; V221-E223 VanDerWaalsContact C-N 3.3Å; V221-E223 PolarHBondContact O-N 3.33Å; V221-I224 PolarHBondContact O-N 2.96Å; V221-V225 HydrophobicContact CG1-CG2 4.45Å; V221-V225 WeakPolarHBondContact O-CG2 3.45Å; V221-V225 PolarHBondContact O-N 2.82Å
222I92.8Very high86.1Confident89 Ų8967.5 Ų67.546%0.45638%0.383SS..Hα-helixtrans-59-43.7175.8-65.6167.3000110.6L218 L219 V225 T226L218-I222 HydrophobicContact CG-CD1 4.04Å; L218-I222 HydrophobicContact CG-CG1 4.49Å; L218-I222 WeakPolarHBondContact O-CG1 3.35Å; L218-I222 PolarHBondContact O-N 3.01Å; L219-I222 PolarHBondContact O-N 2.85Å; I222-V225 PolarHBondContact O-N 3.31Å; I222-T226 WeakPolarHBondContact O-CB 3.3Å; I222-T226 PolarHBondContact O-N 3.23Å; I222-T226 PolarHBondContact O-OG1 2.81Å
223E92.6Very high88.2Confident60 Ų6065.9 Ų65.928%0.2838%0.377SS..Hα-helixtrans-58.7-49.1176.2-176174.8-159.700111.6L136 A196 L219 T220 V221 T226 I227L136-E223 HydrophobicContact CD2-CG 4.41Å; A196-E223 VanDerWaalsContact CB-OE1 3.28Å; A196-E223 WeakPolarHBondContact CB-OE1 3.32Å; L219-E223 WeakPolarHBondContact O-CB 3.44Å; L219-E223 PolarHBondContact O-N 3.25Å; T220-E223 PolarHBondContact O-N 2.86Å; V221-E223 VanDerWaalsContact C-N 3.3Å; V221-E223 PolarHBondContact O-N 3.33Å; E223-T226 PolarHBondContact O-N 2.84Å; E223-I227 HydrophobicContact CG-CD1 4.21Å; E223-I227 VanDerWaalsContact O-CG1 3.27Å; E223-I227 WeakPolarHBondContact O-CG1 3.47Å; E223-I227 PolarHBondContact O-N 3.45Å
224I95.1Very high90.1Very high32 Ų3265.2 Ų65.216%0.16436%0.363CS..Hα-helixtrans-60.7-49.5176.7-68.6166.2000110.8A135 L136 T220 V221 T226 I227 W228A135-I224 HydrophobicContact CB-CD1 3.89Å; L136-I224 HydrophobicContact CD2-CD1 4.46Å; L136-I224 HydrophobicContact CD2-CG1 3.8Å; T220-I224 HydrophobicContact CG2-CD1 4.1Å; T220-I224 VanDerWaalsContact O-CG1 3.3Å; T220-I224 WeakPolarHBondContact O-CG1 3.48Å; T220-I224 PolarHBondContact O-N 3.48Å; V221-I224 PolarHBondContact O-N 2.96Å; I224-T226 PolarHBondContact O-N 3.48Å; I224-I227 WeakPolarHBondContact O-CB 3.38Å; I224-I227 PolarHBondContact O-N 3.3Å; I224-I227 VanDerWaalsContact O-N 3.1Å; I224-W228 PolarHBondContact O-N 3.47Å
225V96.5Very high91.9Very high83 Ų8359 Ų5950%0.50333%0.325SS..Hα-helixtrans-58.1-41.8179.3171.40000110.8V221 I222 W228 V229V221-V225 HydrophobicContact CG1-CG2 4.45Å; V221-V225 WeakPolarHBondContact O-CG2 3.45Å; V221-V225 PolarHBondContact O-N 2.82Å; I222-V225 PolarHBondContact O-N 3.31Å; V225-W228 PolarHBondContact O-N 3.4Å; V225-V229 HydrophobicContact CG1-CG2 4.25Å; V225-V229 WeakPolarHBondContact O-CB 3.26Å; V225-V229 WeakPolarHBondContact O-CG2 3.5Å; V225-V229 PolarHBondContact O-N 3.33Å
226T96.6Very high93.3Very high81 Ų8160.8 Ų60.850%0.49733%0.329SS..Hα-helixtrans-62.7-43.6176.9-54.80000111.4I222 E223 I224 W228 V229 L230I222-T226 WeakPolarHBondContact O-CB 3.3Å; I222-T226 PolarHBondContact O-N 3.23Å; I222-T226 PolarHBondContact O-OG1 2.81Å; E223-T226 PolarHBondContact O-N 2.84Å; I224-T226 PolarHBondContact O-N 3.48Å; T226-W228 VanDerWaalsContact C-N 3.32Å; T226-W228 PolarHBondContact O-N 3.35Å; T226-V229 PolarHBondContact O-N 3.22Å; T226-L230 WeakPolarHBondContact O-CB 3.43Å; T226-L230 PolarHBondContact O-N 2.93Å
227I96.9Very high93.9Very high12 Ų1258.1 Ų58.16%0.06232%0.317CS..Hα-helixtrans-57.8-46.5176.2-71.1166.6000110.6L136 I189 L192 A196 E223 I224 S231L136-I227 HydrophobicContact CD2-CD1 4.21Å; I189-I227 HydrophobicContact CG2-CG2 4.46Å; L192-I227 HydrophobicContact CB-CB 4.39Å; L192-I227 HydrophobicContact CB-CG1 4.04Å; L192-I227 HydrophobicContact CB-CG2 3.77Å; L192-I227 HydrophobicContact CD1-CG2 4.34Å; A196-I227 HydrophobicContact CB-CD1 3.99Å; E223-I227 HydrophobicContact CG-CD1 4.21Å; E223-I227 VanDerWaalsContact O-CG1 3.27Å; E223-I227 WeakPolarHBondContact O-CG1 3.47Å; E223-I227 PolarHBondContact O-N 3.45Å; I224-I227 WeakPolarHBondContact O-CB 3.38Å; I224-I227 PolarHBondContact O-N 3.3Å; I224-I227 VanDerWaalsContact O-N 3.1Å; I227-S231 VanDerWaalsContact O-CB 3.25Å; I227-S231 WeakPolarHBondContact O-CB 3.28Å; I227-S231 PolarHBondContact O-N 2.82Å; I227-S231 PolarHBondContact O-OG 3.47Å
228W97.9Very high94.4Very high65 Ų6556 Ų5625%0.24630%0.303CS..Hα-helixtrans-66.2-50.7-179.2-82.572.2000112.1S139 L142 I146 I189 I224 V225 T226 L230 S231 L232S139-W228 PolarHBondContact OG-NE1 3.49Å; L142-W228 HydrophobicContact CB-CZ2 4.25Å; L142-W228 HydrophobicContact CD2-CH2 3.71Å; L142-W228 HydrophobicContact CD2-CZ2 3.61Å; L142-W228 HydrophobicContact CG-CH2 3.88Å; L142-W228 HydrophobicContact CG-CZ2 3.91Å; I146-W228 HydrophobicContact CD1-CH2 3.73Å; I146-W228 HydrophobicContact CD1-CZ3 4.13Å; I189-W228 HydrophobicContact CD1-CD2 3.8Å; I189-W228 HydrophobicContact CD1-CE3 3.73Å; I189-W228 HydrophobicContact CD1-CG 4.47Å; I189-W228 HydrophobicContact CD1-CH2 3.93Å; I189-W228 HydrophobicContact CD1-CZ2 3.97Å; I189-W228 HydrophobicContact CD1-CZ3 3.81Å; I189-W228 HydrophobicContact CG1-CD2 4.4Å; I224-W228 PolarHBondContact O-N 3.47Å; V225-W228 PolarHBondContact O-N 3.4Å; T226-W228 VanDerWaalsContact C-N 3.32Å; T226-W228 PolarHBondContact O-N 3.35Å; W228-L230 PolarHBondContact O-N 2.84Å; W228-S231 PolarHBondContact O-N 2.98Å; W228-L232 WeakPolarHBondContact O-CB 3.49Å; W228-L232 VanDerWaalsContact O-CG 3.24Å; W228-L232 WeakPolarHBondContact O-CG 3.45Å; W228-L232 PolarHBondContact O-N 3.42Å
229V97.9Very high94.7Very high76 Ų7651 Ų5146%0.46128%0.281SS..Hα-helixtrans-59.6-47.8179.9170.70000110.5V225 T226 S231 L232 I233V225-V229 HydrophobicContact CG1-CG2 4.25Å; V225-V229 WeakPolarHBondContact O-CB 3.26Å; V225-V229 WeakPolarHBondContact O-CG2 3.5Å; V225-V229 PolarHBondContact O-N 3.33Å; T226-V229 PolarHBondContact O-N 3.22Å; V229-S231 PolarHBondContact O-N 2.88Å; V229-L232 PolarHBondContact O-N 3.22Å; V229-I233 HydrophobicContact CG1-CD1 3.65Å; V229-I233 HydrophobicContact CG1-CG1 4.43Å; V229-I233 VanDerWaalsContact O-CG1 3.25Å; V229-I233 WeakPolarHBondContact O-CG1 3.22Å; V229-I233 PolarHBondContact O-N 2.93Å
230L97.1Very high94.9Very high68 Ų6849.4 Ų49.436%0.35628%0.275SS..Hα-helixtrans-61.7-44178.4-176.958.6000111.4L192 T226 W228 L232 I233 L234L192-L230 HydrophobicContact CD1-CB 4.19Å; L192-L230 HydrophobicContact CD1-CD2 3.82Å; L192-L230 HydrophobicContact CD1-CG 4.06Å; L192-L230 HydrophobicContact CD2-CD2 4.37Å; T226-L230 WeakPolarHBondContact O-CB 3.43Å; T226-L230 PolarHBondContact O-N 2.93Å; W228-L230 PolarHBondContact O-N 2.84Å; L230-L232 VanDerWaalsContact C-N 3.35Å; L230-L232 PolarHBondContact O-N 3.26Å; L230-I233 PolarHBondContact O-N 2.89Å; L230-L234 HydrophobicContact CD1-CD1 4.17Å; L230-L234 HydrophobicContact CD1-CG 4.13Å; L230-L234 HydrophobicContact CG-CD1 4.08Å; L230-L234 HydrophobicContact CG-CG 4.43Å; L230-L234 WeakPolarHBondContact O-CB 3.17Å; L230-L234 VanDerWaalsContact O-CG 3.24Å; L230-L234 WeakPolarHBondContact O-CG 3.27Å; L230-L234 PolarHBondContact O-N 2.81Å
231S97.7Very high95.1Very high0 Ų049.2 Ų49.20%027%0.274CS..Hα-helixtrans-63.2-40.2179.4-59.10000112.8A185 G188 I189 I227 W228 V229 A235A185-S231 WeakPolarHBondContact O-CB 3.37Å; G188-S231 PolarHBondContact O-OG 3.22Å; I189-S231 WeakPolarHBondContact CA-OG 3.19Å; I189-S231 PolarHBondContact N-OG 3.48Å; I227-S231 VanDerWaalsContact O-CB 3.25Å; I227-S231 WeakPolarHBondContact O-CB 3.28Å; I227-S231 PolarHBondContact O-N 2.82Å; I227-S231 PolarHBondContact O-OG 3.47Å; W228-S231 PolarHBondContact O-N 2.98Å; V229-S231 PolarHBondContact O-N 2.88Å; S231-A235 WeakPolarHBondContact O-CB 3.2Å; S231-A235 PolarHBondContact O-N 3.21Å
232L97.1Very high95.1Very high64 Ų6447.5 Ų47.534%0.33526%0.261SS..Hα-helixtrans-66.3-45176.7-69.1167.3000110.9F181 A185 W228 V229 L230 L234 A235 V236F181-L232 HydrophobicContact CE1-CD2 4.09Å; F181-L232 WeakPolarHBondContact CE2-O 3.41Å; F181-L232 HydrophobicContact CZ-CB 4.5Å; F181-L232 HydrophobicContact CZ-CD2 3.69Å; A185-L232 HydrophobicContact CB-CD2 3.92Å; W228-L232 WeakPolarHBondContact O-CB 3.49Å; W228-L232 VanDerWaalsContact O-CG 3.24Å; W228-L232 WeakPolarHBondContact O-CG 3.45Å; W228-L232 PolarHBondContact O-N 3.42Å; V229-L232 PolarHBondContact O-N 3.22Å; L230-L232 VanDerWaalsContact C-N 3.35Å; L230-L232 PolarHBondContact O-N 3.26Å; L232-L234 PolarHBondContact O-N 3.41Å; L232-A235 PolarHBondContact O-N 3.18Å; L232-A235 VanDerWaalsContact O-N 3.16Å; L232-V236 WeakPolarHBondContact O-CG2 3.47Å; L232-V236 PolarHBondContact O-N 2.91Å
233I97.3Very high95.1Very high102 Ų10245.6 Ų45.652%0.52325%0.252SS..Hα-helixtrans-59.3-47.1177.7-70.6167.6000110.8V229 L230 A235 V236V229-I233 HydrophobicContact CG1-CD1 3.65Å; V229-I233 HydrophobicContact CG1-CG1 4.43Å; V229-I233 VanDerWaalsContact O-CG1 3.25Å; V229-I233 WeakPolarHBondContact O-CG1 3.22Å; V229-I233 PolarHBondContact O-N 2.93Å; L230-I233 PolarHBondContact O-N 2.89Å; I233-A235 PolarHBondContact O-N 2.85Å; I233-V236 WeakPolarHBondContact O-CB 3.31Å; I233-V236 WeakPolarHBondContact O-CG2 3.28Å; I233-V236 PolarHBondContact O-N 3.48Å; I233-V236 VanDerWaalsContact O-N 3.16Å
234L95.3Very high94.9Very high33 Ų3343.6 Ų43.617%0.17324%0.243CC..Hα-helixtrans-65.4-22.1-179.8-67.4179.4000113.3L230 L232 P237 W276 F280L230-L234 HydrophobicContact CD1-CD1 4.17Å; L230-L234 HydrophobicContact CD1-CG 4.13Å; L230-L234 HydrophobicContact CG-CD1 4.08Å; L230-L234 HydrophobicContact CG-CG 4.43Å; L230-L234 WeakPolarHBondContact O-CB 3.17Å; L230-L234 VanDerWaalsContact O-CG 3.24Å; L230-L234 WeakPolarHBondContact O-CG 3.27Å; L230-L234 PolarHBondContact O-N 2.81Å; L232-L234 PolarHBondContact O-N 3.41Å; L234-P237 WeakPolarHBondContact O-CD 3.19Å; L234-W276 HydrophobicContact CD1-CZ2 4.41Å; L234-W276 HydrophobicContact CD2-CH2 4.24Å; L234-W276 HydrophobicContact CD2-CZ2 3.76Å; L234-F280 HydrophobicContact CD1-CD1 3.97Å; L234-F280 HydrophobicContact CD1-CE1 3.22Å; L234-F280 HydrophobicContact CD1-CE2 4.04Å; L234-F280 HydrophobicContact CD1-CZ 3.25Å
235A96.1Very high94.5Very high0 Ų043.6 Ų43.60%024%0.244CC..Hα-helixtrans-86.8-16.7177.300000113.8F181 K184 A185 S231 L232 I233 P237 E238F181-A235 HydrophobicContact CD2-CB 3.69Å; F181-A235 WeakPolarHBondContact CD2-O 3.32Å; F181-A235 HydrophobicContact CE2-CB 3.83Å; F181-A235 WeakPolarHBondContact O-CB 3.32Å; K184-A235 HydrophobicContact CB-CB 3.9Å; A185-A235 HydrophobicContact CB-CB 3.89Å; S231-A235 WeakPolarHBondContact O-CB 3.2Å; S231-A235 PolarHBondContact O-N 3.21Å; L232-A235 PolarHBondContact O-N 3.18Å; L232-A235 VanDerWaalsContact O-N 3.16Å; I233-A235 PolarHBondContact O-N 2.85Å; A235-P237 VanDerWaalsContact C-N 3.33Å; A235-E238 VanDerWaalsContact O-CB 3.3Å; A235-E238 WeakPolarHBondContact O-CB 3.42Å; A235-E238 PolarHBondContact O-N 2.99Å
236V95.4Very high93.9Very high73 Ų7344.5 Ų44.544%0.44225%0.25SS..Hα-helixtrans-50.4-43.1-178.21730000113.6F181 L232 I233 E238 A239 V240F181-V236 HydrophobicContact CE2-CG2 4.36Å; L232-V236 WeakPolarHBondContact O-CG2 3.47Å; L232-V236 PolarHBondContact O-N 2.91Å; I233-V236 WeakPolarHBondContact O-CB 3.31Å; I233-V236 WeakPolarHBondContact O-CG2 3.28Å; I233-V236 PolarHBondContact O-N 3.48Å; I233-V236 VanDerWaalsContact O-N 3.16Å; V236-E238 PolarHBondContact O-N 2.99Å; V236-E238 VanDerWaalsContact O-N 3.11Å; V236-A239 PolarHBondContact O-N 3.27Å; V236-V240 HydrophobicContact CG1-CG2 4.16Å; V236-V240 PolarHBondContact O-N 2.85Å
237P93.1Very high93.2Very high27 Ų2744.3 Ų44.318%0.17524%0.242CC..Hα-helixtrans-57.2-29.2179.4-27.737.3000113.9L234 A235 V240 C241 Y269L234-P237 WeakPolarHBondContact O-CD 3.19Å; A235-P237 VanDerWaalsContact C-N 3.33Å; P237-V240 PolarHBondContact O-N 3.36Å; P237-C241 VanDerWaalsContact O-CB 3.29Å; P237-C241 WeakPolarHBondContact O-CB 3.31Å; P237-C241 PolarHBondContact O-N 2.87Å; P237-C241 PolarHBondContact O-SG 3.26Å; P237-Y269 HydrophobicContact CB-CD1 4.43Å; P237-Y269 HydrophobicContact CB-CD2 3.74Å; P237-Y269 HydrophobicContact CB-CE1 4.12Å; P237-Y269 HydrophobicContact CB-CE2 3.39Å; P237-Y269 HydrophobicContact CB-CG 4.24Å; P237-Y269 HydrophobicContact CG-CD2 4.48Å; P237-Y269 HydrophobicContact CG-CE2 4.14Å
238E93.2Very high92.3Very high2 Ų249.9 Ų49.91%0.00927%0.272CS..Hα-helixtrans-66.9-43.4177.3-60-83.9178.800111.2P180 K184 A235 V236 V240 F242 Y269 K273P180-E238 HydrophobicContact CB-CB 4.13Å; K184-E238 HydrophobicContact CB-CG 4.09Å; K184-E238 VanDerWaalsContact CE-OE1 3.22Å; K184-E238 WeakPolarHBondContact CE-OE1 3.37Å; K184-E238 HydrophobicContact CG-CG 3.48Å; K184-E238 VanDerWaalsContact CG-CG 3.48Å; K184-E238 WeakPolarHBondContact CG-OE1 3.32Å; A235-E238 VanDerWaalsContact O-CB 3.3Å; A235-E238 WeakPolarHBondContact O-CB 3.42Å; A235-E238 PolarHBondContact O-N 2.99Å; V236-E238 PolarHBondContact O-N 2.99Å; V236-E238 VanDerWaalsContact O-N 3.11Å; E238-V240 VanDerWaalsContact C-N 3.29Å; E238-V240 PolarHBondContact O-N 3.28Å; E238-F242 WeakPolarHBondContact O-CB 3.44Å; E238-F242 VanDerWaalsContact O-CD2 3.25Å; E238-F242 WeakPolarHBondContact O-CD2 3.02Å; E238-F242 PolarHBondContact O-N 2.86Å; E238-F242 VanDerWaalsContact O-N 3.1Å; E238-F242 WeakPolarHBondContact OE2-CE2 3.24Å; E238-Y269 WeakPolarHBondContact CG-OH 3.43Å; E238-Y269 PolarHBondContact OE1-OH 3.06Å; E238-K273 WeakPolarHBondContact OE1-CE 3.31Å; E238-K273 IonicContact OE1-NZ 3.62Å; E238-K273 PolarHBondContact OE1-NZ 3.38Å; E238-K273 IonicContact OE2-NZ 2.99Å; E238-K273 PolarHBondContact OE2-NZ 3.24Å
239A93.6Very high90.9Very high28 Ų2851.9 Ų51.923%0.23128%0.283CS..Hα-helixtrans-64.4-35.4176.700000112.4K177 F181 V236K177-A239 WeakPolarHBondContact CG-O 3.43Å; K177-A239 PolarHBondContact NZ-O 3.39Å; F181-A239 HydrophobicContact CB-CB 4.06Å; F181-A239 HydrophobicContact CD2-CB 4.22Å; F181-A239 HydrophobicContact CG-CB 4.33Å; V236-A239 PolarHBondContact O-N 3.27Å
240V92.6Very high89.2Confident70 Ų7052.7 Ų52.742%0.42429%0.292SS..Hα-helixtrans-75-43.9-178.9177.50000111.1V236 P237 E238 M266V236-V240 HydrophobicContact CG1-CG2 4.16Å; V236-V240 PolarHBondContact O-N 2.85Å; P237-V240 PolarHBondContact O-N 3.36Å; E238-V240 VanDerWaalsContact C-N 3.29Å; E238-V240 PolarHBondContact O-N 3.28Å; V240-M266 HydrophobicContact CG1-CE 4.18Å
241C91Very high88Confident2 Ų257.9 Ų57.91%0.01432%0.32CS..Hα-helixtrans-88.1-20.3-170.4-57.90000114.5P237 L259 N260 Y269P237-C241 VanDerWaalsContact O-CB 3.29Å; P237-C241 WeakPolarHBondContact O-CB 3.31Å; P237-C241 PolarHBondContact O-N 2.87Å; P237-C241 PolarHBondContact O-SG 3.26Å; C241-L259 HydrophobicContact CB-CD2 3.61Å; C241-N260 PolarHBondContact O-N 3.46Å; C241-N260 VanDerWaalsContact O-N 3.1Å; C241-Y269 HydrophobicContact CB-CD1 4.04Å; C241-Y269 HydrophobicContact CB-CE1 4.24Å; C241-Y269 WeakPolarHBondContact SG-CD1 3.37Å
242F91.8Very high86.8Confident30 Ų3061 Ų6113%0.13234%0.34CS..EExtended strand (participates in β ladder)trans-81134175.3-85.3-106.6000111.2K177 P180 E238 L259 K273K177-F242 WeakPolarHBondContact CG-O 3.46Å; K177-F242 PolarHBondContact NZ-O 3.25Å; P180-F242 HydrophobicContact CB-CD1 4.33Å; P180-F242 HydrophobicContact CB-CD2 4.11Å; P180-F242 HydrophobicContact CB-CE1 4.35Å; P180-F242 HydrophobicContact CB-CE2 4.17Å; P180-F242 HydrophobicContact CB-CG 4.19Å; P180-F242 HydrophobicContact CB-CZ 4.26Å; P180-F242 HydrophobicContact CG-CB 4.4Å; P180-F242 HydrophobicContact CG-CD1 3.65Å; P180-F242 HydrophobicContact CG-CD2 4.25Å; P180-F242 HydrophobicContact CG-CE1 3.88Å; P180-F242 HydrophobicContact CG-CE2 4.49Å; P180-F242 HydrophobicContact CG-CG 3.82Å; P180-F242 HydrophobicContact CG-CZ 4.3Å; E238-F242 WeakPolarHBondContact O-CB 3.44Å; E238-F242 VanDerWaalsContact O-CD2 3.25Å; E238-F242 WeakPolarHBondContact O-CD2 3.02Å; E238-F242 PolarHBondContact O-N 2.86Å; E238-F242 VanDerWaalsContact O-N 3.1Å; E238-F242 WeakPolarHBondContact OE2-CE2 3.24Å; F242-L259 HydrophobicContact CD2-CD2 3.98Å; F242-L259 HydrophobicContact CD2-CG 4.1Å; F242-L259 HydrophobicContact CE2-CD1 4.12Å; F242-L259 HydrophobicContact CE2-CD2 3.71Å; F242-L259 HydrophobicContact CE2-CG 3.62Å; F242-L259 HydrophobicContact CZ-CD1 4.16Å; F242-L259 HydrophobicContact CZ-CD2 4.5Å; F242-L259 HydrophobicContact CZ-CG 3.92Å; F242-K273 VanDerWaalsContact CE2-NZ 3.33Å
243D91.8Very high86Confident49 Ų4963.4 Ų63.426%0.26236%0.357SS..EExtended strand (participates in β ladder)trans-146.6161.3176.8-150.4-8.1000111.7L173 C176 V245 M258 N260L173-D243 WeakPolarHBondContact CD1-OD1 3.27Å; C176-D243 VanDerWaalsContact SG-C 3.51Å; D243-V245 PolarHBondContact O-N 3.39Å; D243-M258 PolarHBondContact N-O 3.26Å; D243-M258 PolarHBondContact O-N 3.32Å; D243-M258 VanDerWaalsContact O-O 3.05Å; D243-N260 HydrophobicContact CB-CB 3.98Å
244M88.8Confident85.1Confident19 Ų1961.2 Ų61.29%0.09435%0.345CS..EExtended strand (participates in β ladder)trans-83.7109.7174.6-76.1-62.6-78.400109.9F164 D167 L173 C176 R255 T256 C257F164-M244 HydrophobicContact CB-CE 4.33Å; F164-M244 HydrophobicContact CD1-CE 4.09Å; F164-M244 HydrophobicContact CD1-SD 3.95Å; F164-M244 HydrophobicContact CE1-SD 4.42Å; F164-M244 HydrophobicContact CG-CE 4.46Å; F164-M244 HydrophobicContact CG-SD 4.3Å; D167-M244 HydrophobicContact CB-CE 3.67Å; L173-M244 HydrophobicContact CB-CG 4.38Å; L173-M244 HydrophobicContact CD1-CB 4.23Å; L173-M244 HydrophobicContact CD1-CG 4.1Å; C176-M244 HydrophobicContact CB-CG 3.87Å; C176-M244 HydrophobicContact CB-SD 3.9Å; M244-R255 HydrophobicContact CE-CB 4.43Å; M244-R255 HydrophobicContact CE-CG 3.67Å; M244-T256 VanDerWaalsContact SD-C 3.6Å; M244-C257 HydrophobicContact SD-CB 3.76Å
245V87.5Confident84.6Confident32 Ų3263.8 Ų63.819%0.19435%0.352CS..EExtended strand (participates in β ladder)trans-107134.7-177.8-176.70000110.1D243 R255 T256 M258 N260D243-V245 PolarHBondContact O-N 3.39Å; V245-R255 WeakPolarHBondContact O-CA 3.26Å; V245-T256 PolarHBondContact N-O 2.94Å; V245-T256 PolarHBondContact O-N 3.4Å; V245-M258 HydrophobicContact CB-CG 3.85Å; V245-M258 HydrophobicContact CB-SD 4.06Å; V245-M258 HydrophobicContact CG1-SD 4.32Å; V245-M258 HydrophobicContact CG2-CG 3.72Å; V245-M258 HydrophobicContact CG2-SD 4.29Å; V245-N260 HydrophobicContact CG2-CB 3.74Å
246T84.3Confident84.1Confident102 Ų10265.1 Ų65.163%0.62636%0.361SS*.EExtended strand (participates in β ladder)trans-98.4128.317350.50000110.4M254 R255T246-M254 CarbonylContact C-O 3.6Å; T246-M254 WeakPolarHBondContact CA-O 3.31Å; T246-R255 HydrophobicContact CG2-CB 4.08Å; T246-R255 HydrophobicContact CG2-CG 3.69Å
247F80.6Confident83.8Confident76 Ų7662.4 Ų62.433%0.33335%0.345SS..EExtended strand (participates in β ladder)trans-131.7144172.354.2-90.2000111.2F249 M254 T256F247-F249 HydrophobicContact CD2-CB 4.19Å; F247-F249 HydrophobicContact CE2-CB 4.42Å; F247-M254 HydrophobicContact CD2-CB 4.13Å; F247-M254 HydrophobicContact CE1-CB 4.42Å; F247-M254 HydrophobicContact CE2-CB 3.61Å; F247-M254 HydrophobicContact CE2-CG 4.36Å; F247-M254 HydrophobicContact CE2-SD 4.16Å; F247-M254 HydrophobicContact CZ-CB 3.77Å; F247-M254 PolarHBondContact N-O 2.76Å; F247-M254 PolarHBondContact O-N 2.94Å; F247-T256 HydrophobicContact CE1-CG2 3.62Å; F247-T256 HydrophobicContact CZ-CG2 4.33Å
248N78.4Confident83.6Confident129 Ų12965 Ų6569%0.6936%0.355SS*.EExtended strand (participates in β ladder)trans-93.8108.8175.3-72.9-17.9000108.9T253N248-T253 WeakPolarHBondContact OD1-CG2 3.23Å
249F68.3Low83.3Confident108 Ų10867.3 Ų67.347%0.47437%0.368SS..EExtended strand (participates in β ladder)trans-116.2121.8174.6-163.4-94.1000108.8F247 N251 T252F247-F249 HydrophobicContact CD2-CB 4.19Å; F247-F249 HydrophobicContact CE2-CB 4.42Å; F249-N251 PolarHBondContact O-N 3.45Å; F249-T252 PolarHBondContact N-O 3.49Å; F249-T252 PolarHBondContact O-N 3.45Å
250S62.1Low83Confident93 Ų9368.3 Ų68.365%0.6537%0.369SS*.THydrogen-bonded Turntrans45.654.9177.256.40000114.1T252S250-T252 PolarHBondContact O-N 2.92Å; S250-T252 VanDerWaalsContact O-N 3.15Å
251N71.6Confident82.6Confident177 Ų17768 Ų6895%0.94737%0.369SS*.THydrogen-bonded Turntrans6411.4179.3-122.823.6000116.1F249F249-N251 PolarHBondContact O-N 3.45Å
252T73.9Confident82.3Confident66 Ų6675.1 Ų75.141%0.40540%0.402SS..EExtended strand (participates in β ladder)trans-114.5127.8172.3-52.20000109.8F249 S250 M254F249-T252 PolarHBondContact N-O 3.49Å; F249-T252 PolarHBondContact O-N 3.45Å; S250-T252 PolarHBondContact O-N 2.92Å; S250-T252 VanDerWaalsContact O-N 3.15Å; T252-M254 HydrophobicContact CG2-CE 4.48Å; T252-M254 HydrophobicContact CG2-CG 4.39Å; T252-M254 PolarHBondContact O-N 2.83Å
253T79.2Confident82.2Confident114 Ų11476.2 Ų76.270%0.69941%0.413SS*.EExtended strand (participates in β ladder)trans-76.2116.4170.449.10000108.8N248N248-T253 WeakPolarHBondContact OD1-CG2 3.23Å
254M79.1Confident82.1Confident56 Ų5680.2 Ų80.228%0.27643%0.434SS..EExtended strand (participates in β ladder)trans-113.7134.5174-71.1-169.6171.200110.1T246 F247 T252T246-M254 CarbonylContact C-O 3.6Å; T246-M254 WeakPolarHBondContact CA-O 3.31Å; F247-M254 HydrophobicContact CD2-CB 4.13Å; F247-M254 HydrophobicContact CE1-CB 4.42Å; F247-M254 HydrophobicContact CE2-CB 3.61Å; F247-M254 HydrophobicContact CE2-CG 4.36Å; F247-M254 HydrophobicContact CE2-SD 4.16Å; F247-M254 HydrophobicContact CZ-CB 3.77Å; F247-M254 PolarHBondContact N-O 2.76Å; F247-M254 PolarHBondContact O-N 2.94Å; T252-M254 HydrophobicContact CG2-CE 4.48Å; T252-M254 HydrophobicContact CG2-CG 4.39Å; T252-M254 PolarHBondContact O-N 2.83Å
255R83.6Confident82.1Confident86 Ų8684.7 Ų84.733%0.32545%0.454SS..EExtended strand (participates in β ladder)trans-113.5126.8175.1-163.5178.1-179.5-1766.5109.2D167 M244 V245 T246D167-R255 HydrophobicContact CB-CB 4.34Å; D167-R255 VanDerWaalsContact O-CD 3.29Å; D167-R255 WeakPolarHBondContact O-CD 3.03Å; D167-R255 PolarHBondContact O-NH1 3.29Å; M244-R255 HydrophobicContact CE-CB 4.43Å; M244-R255 HydrophobicContact CE-CG 3.67Å; V245-R255 WeakPolarHBondContact O-CA 3.26Å; T246-R255 HydrophobicContact CG2-CB 4.08Å; T246-R255 HydrophobicContact CG2-CG 3.69Å
256T85.7Confident82.2Confident29 Ų2984.9 Ų84.918%0.17845%0.453CS..EExtended strand (participates in β ladder)trans-143.5159.4-179.7-150.90000112M244 V245 F247 M258M244-T256 VanDerWaalsContact SD-C 3.6Å; V245-T256 PolarHBondContact N-O 2.94Å; V245-T256 PolarHBondContact O-N 3.4Å; F247-T256 HydrophobicContact CE1-CG2 3.62Å; F247-T256 HydrophobicContact CZ-CG2 4.33Å; T256-M258 HydrophobicContact CG2-CB 4.43Å; T256-M258 HydrophobicContact CG2-CE 3.78Å; T256-M258 HydrophobicContact CG2-CG 4.18Å; T256-M258 HydrophobicContact CG2-SD 4.44Å
257C89.6Confident82.4Confident15 Ų1588 Ų8810%0.10145%0.453CS..EExtended strand (participates in β ladder)trans-86117.2175.7-1760000110.3F164 C176 M244F164-C257 HydrophobicContact CD1-CB 4.34Å; F164-C257 HydrophobicContact CD2-CB 3.4Å; F164-C257 VanDerWaalsContact CD2-CB 3.4Å; F164-C257 HydrophobicContact CE1-CB 4.36Å; F164-C257 HydrophobicContact CE2-CB 3.43Å; F164-C257 VanDerWaalsContact CE2-CB 3.43Å; F164-C257 HydrophobicContact CG-CB 3.89Å; F164-C257 HydrophobicContact CZ-CB 3.94Å; C176-C257 WeakPolarHBondContact CA-SG 3.39Å; C176-C257 HydrophobicContact CB-CB 3.71Å; C176-C257 WeakPolarHBondContact CB-SG 3.45Å; C176-C257 PolarHBondContact O-SG 2.67Å; C176-C257 WeakPolarHBondContact SG-CA 3.22Å; C176-C257 WeakPolarHBondContact SG-CB 3.11Å; C176-C257 CovalentContact SG-SG 2.03Å; C176-C257 PolarHBondContact SG-SG 2.93Å; M244-C257 HydrophobicContact SD-CB 3.76Å
258M88.5Confident83Confident81 Ų8191.1 Ų91.140%0.39947%0.467SS..EExtended strand (participates in β ladder)trans-149.9167178.755.6170.939.100112.4D243 V245 T256 N260D243-M258 PolarHBondContact N-O 3.26Å; D243-M258 PolarHBondContact O-N 3.32Å; D243-M258 VanDerWaalsContact O-O 3.05Å; V245-M258 HydrophobicContact CB-CG 3.85Å; V245-M258 HydrophobicContact CB-SD 4.06Å; V245-M258 HydrophobicContact CG1-SD 4.32Å; V245-M258 HydrophobicContact CG2-CG 3.72Å; V245-M258 HydrophobicContact CG2-SD 4.29Å; T256-M258 HydrophobicContact CG2-CB 4.43Å; T256-M258 HydrophobicContact CG2-CE 3.78Å; T256-M258 HydrophobicContact CG2-CG 4.18Å; T256-M258 HydrophobicContact CG2-SD 4.44Å; M258-N260 PolarHBondContact O-N 2.82Å
259L87.2Confident83.5Confident51 Ų5185.8 Ų85.827%0.26744%0.437SS..EExtended strand (participates in β ladder)trans-65.3120.3171.6-77.2147.2000109.3C241 F242 P261 Y269 K273C241-L259 HydrophobicContact CB-CD2 3.61Å; F242-L259 HydrophobicContact CD2-CD2 3.98Å; F242-L259 HydrophobicContact CD2-CG 4.1Å; F242-L259 HydrophobicContact CE2-CD1 4.12Å; F242-L259 HydrophobicContact CE2-CD2 3.71Å; F242-L259 HydrophobicContact CE2-CG 3.62Å; F242-L259 HydrophobicContact CZ-CD1 4.16Å; F242-L259 HydrophobicContact CZ-CD2 4.5Å; F242-L259 HydrophobicContact CZ-CG 3.92Å; L259-P261 WeakPolarHBondContact O-CD 3.34Å; L259-Y269 HydrophobicContact CD2-CD1 4.42Å; L259-Y269 HydrophobicContact CD2-CE1 4.21Å; L259-K273 HydrophobicContact CD1-CD 4.05Å
260N87.5Confident84.5Confident49 Ų4982.5 Ų82.526%0.26243%0.426SS..  trans-119.288.4179.3-171.428000110.2C241 D243 V245 M258 Q262C241-N260 PolarHBondContact O-N 3.46Å; C241-N260 VanDerWaalsContact O-N 3.1Å; D243-N260 HydrophobicContact CB-CB 3.98Å; V245-N260 HydrophobicContact CG2-CB 3.74Å; M258-N260 PolarHBondContact O-N 2.82Å; N260-Q262 PolarHBondContact ND2-NE2 3.31Å; N260-Q262 PolarHBondContact O-N 2.89Å
261P84.8Confident85.7Confident64 Ų6483.5 Ų83.542%0.41642%0.42SS..  trans-72.9104.1-176.128.9-33.2000111L259 M266 R267L259-P261 WeakPolarHBondContact O-CD 3.34Å; P261-M266 HydrophobicContact CB-CB 4.07Å; P261-R267 HydrophobicContact CB-CB 4.42Å
262Q84.9Confident86.7Confident152 Ų15276.5 Ų76.571%0.7139%0.387SS*.  trans-100-24.2175.2-65.3-163-9.500113.8N260 M266N260-Q262 PolarHBondContact ND2-NE2 3.31Å; N260-Q262 PolarHBondContact O-N 2.89Å; Q262-M266 HydrophobicContact CB-SD 4.26Å; Q262-M266 PolarHBondContact N-SD 2.97Å
263S89.6Confident87.5Confident52 Ų5274.1 Ų74.136%0.36437%0.371SS..SBendtrans-115.8161.2178.673.40000112.3F265 M266 R267S263-F265 PolarHBondContact O-N 3.01Å; S263-M266 PolarHBondContact O-N 3.01Å; S263-M266 WeakPolarHBondContact OG-CG 3.38Å; S263-M266 PolarHBondContact OG-N 3.35Å; S263-R267 PolarHBondContact O-N 2.92Å
264D89.3Confident88.1Confident133 Ų13370.3 Ų70.371%0.71135%0.346SS*.Hα-helixtrans-57.4-37.9177.2-69.4-42.2000112.3R267 F268D264-R267 PolarHBondContact O-N 2.88Å; D264-F268 PolarHBondContact O-N 3.38Å
265F88.8Confident88.8Confident114 Ų11473.6 Ų73.650%0.536%0.356SS..Hα-helixtrans-61.3-46173.8173.8-99000112.1S263 R267 F268 Y269S263-F265 PolarHBondContact O-N 3.01Å; F265-R267 VanDerWaalsContact C-N 3.28Å; F265-R267 PolarHBondContact O-N 3.49Å; F265-F268 PolarHBondContact O-N 3.1Å; F265-Y269 WeakPolarHBondContact O-CB 3.17Å; F265-Y269 PolarHBondContact O-N 3.23Å
266M88.6Confident89.3Confident35 Ų3574.3 Ų74.317%0.17236%0.359CS..Hα-helixtrans-65.4-34178.8-64.2175.5-160.600111.8V240 P261 Q262 S263 Y269 T270V240-M266 HydrophobicContact CG1-CE 4.18Å; P261-M266 HydrophobicContact CB-CB 4.07Å; Q262-M266 HydrophobicContact CB-SD 4.26Å; Q262-M266 PolarHBondContact N-SD 2.97Å; S263-M266 PolarHBondContact O-N 3.01Å; S263-M266 WeakPolarHBondContact OG-CG 3.38Å; S263-M266 PolarHBondContact OG-N 3.35Å; M266-Y269 PolarHBondContact O-N 3.39Å; M266-T270 WeakPolarHBondContact O-CB 3.47Å; M266-T270 PolarHBondContact O-N 2.74Å; M266-T270 PolarHBondContact O-OG1 2.92Å
267R89.9Confident89.7Confident168 Ų16873 Ų7363%0.63435%0.351SS*.Hα-helixtrans-66.5-47.4175-164175.878.81692.5111.1P261 S263 D264 F265 Y269 T270 E271P261-R267 HydrophobicContact CB-CB 4.42Å; S263-R267 PolarHBondContact O-N 2.92Å; D264-R267 PolarHBondContact O-N 2.88Å; F265-R267 VanDerWaalsContact C-N 3.28Å; F265-R267 PolarHBondContact O-N 3.49Å; R267-Y269 VanDerWaalsContact C-N 3.33Å; R267-Y269 PolarHBondContact O-N 3.24Å; R267-T270 PolarHBondContact O-N 2.99Å; R267-E271 PolarHBondContact O-N 3.45Å; R267-E271 VanDerWaalsContact O-N 3.11Å
268F91.6Very high89.9Confident141 Ų14175.3 Ų75.362%0.61836%0.359SS*.Hα-helixtrans-56.9-47.5173.2170.9-98.8000111.4D264 F265 T270 E271 A272D264-F268 PolarHBondContact O-N 3.38Å; F265-F268 PolarHBondContact O-N 3.1Å; F268-T270 PolarHBondContact O-N 3.1Å; F268-E271 PolarHBondContact O-N 2.64Å; F268-A272 HydrophobicContact CE1-CB 4.25Å; F268-A272 HydrophobicContact CE2-CB 4.49Å; F268-A272 HydrophobicContact CZ-CB 4.16Å; F268-A272 WeakPolarHBondContact O-CB 3.5Å; F268-A272 PolarHBondContact O-N 3.35Å
269Y90.6Very high90.2Very high18 Ų1872.9 Ų72.97%0.07136%0.355CS..Hα-helixtrans-61.5-44.7178.5176.7-101.9000111.8P237 E238 C241 L259 F265 M266 R267 E271 A272 K273P237-Y269 HydrophobicContact CB-CD1 4.43Å; P237-Y269 HydrophobicContact CB-CD2 3.74Å; P237-Y269 HydrophobicContact CB-CE1 4.12Å; P237-Y269 HydrophobicContact CB-CE2 3.39Å; P237-Y269 HydrophobicContact CB-CG 4.24Å; P237-Y269 HydrophobicContact CG-CD2 4.48Å; P237-Y269 HydrophobicContact CG-CE2 4.14Å; E238-Y269 WeakPolarHBondContact CG-OH 3.43Å; E238-Y269 PolarHBondContact OE1-OH 3.06Å; C241-Y269 HydrophobicContact CB-CD1 4.04Å; C241-Y269 HydrophobicContact CB-CE1 4.24Å; C241-Y269 WeakPolarHBondContact SG-CD1 3.37Å; L259-Y269 HydrophobicContact CD2-CD1 4.42Å; L259-Y269 HydrophobicContact CD2-CE1 4.21Å; F265-Y269 WeakPolarHBondContact O-CB 3.17Å; F265-Y269 PolarHBondContact O-N 3.23Å; M266-Y269 PolarHBondContact O-N 3.39Å; R267-Y269 VanDerWaalsContact C-N 3.33Å; R267-Y269 PolarHBondContact O-N 3.24Å; Y269-E271 VanDerWaalsContact C-N 3.27Å; Y269-E271 PolarHBondContact O-N 3.32Å; Y269-A272 PolarHBondContact O-N 2.88Å; Y269-A272 VanDerWaalsContact O-N 3.16Å; Y269-K273 HydrophobicContact CE1-CB 4.3Å; Y269-K273 HydrophobicContact CE1-CD 3.94Å; Y269-K273 HydrophobicContact CE1-CG 4.32Å; Y269-K273 WeakPolarHBondContact O-CA 2.97Å; Y269-K273 WeakPolarHBondContact O-CB 3.25Å; Y269-K273 PolarHBondContact O-N 2.88Å
270T87.9Confident90.5Very high39 Ų3972.2 Ų72.224%0.23935%0.35CS..Hα-helixtrans-58.6-41.3179-59.30000111.4M266 R267 F268M266-T270 WeakPolarHBondContact O-CB 3.47Å; M266-T270 PolarHBondContact O-N 2.74Å; M266-T270 PolarHBondContact O-OG1 2.92Å; R267-T270 PolarHBondContact O-N 2.99Å; F268-T270 PolarHBondContact O-N 3.1Å
271E88.4Confident90.7Very high113 Ų11370 Ų7053%0.52834%0.338SS..Hα-helixtrans-69.9-44.7174.2-69.9-57.7139.700112.1R267 F268 Y269 K273 K348R267-E271 PolarHBondContact O-N 3.45Å; R267-E271 VanDerWaalsContact O-N 3.11Å; F268-E271 PolarHBondContact O-N 2.64Å; Y269-E271 VanDerWaalsContact C-N 3.27Å; Y269-E271 PolarHBondContact O-N 3.32Å; E271-K273 PolarHBondContact O-N 3.23Å; E271-K348 PolarHBondContact O-NZ 3.08Å; E271-K348 IonicContact OE2-NZ 3.6Å
272A91.9Very high91.1Very high31 Ų3167.7 Ų67.726%0.25632%0.321SS..Hα-helixtrans-76.2-22.4-176.300000113.5F268 Y269 D274 W275 W276F268-A272 HydrophobicContact CE1-CB 4.25Å; F268-A272 HydrophobicContact CE2-CB 4.49Å; F268-A272 HydrophobicContact CZ-CB 4.16Å; F268-A272 WeakPolarHBondContact O-CB 3.5Å; F268-A272 PolarHBondContact O-N 3.35Å; Y269-A272 PolarHBondContact O-N 2.88Å; Y269-A272 VanDerWaalsContact O-N 3.16Å; A272-D274 PolarHBondContact O-N 3.4Å; A272-W275 PolarHBondContact O-N 3.42Å; A272-W276 WeakPolarHBondContact O-CB 3.4Å; A272-W276 PolarHBondContact O-N 3.42Å
273K91.8Very high91.6Very high16 Ų1662.1 Ų62.17%0.0730%0.298CS..Hα-helixtrans-52.1-54.5-166.2173.5177.5-179.21600113.6E238 F242 L259 Y269 E271 W275 W276 L277E238-K273 WeakPolarHBondContact OE1-CE 3.31Å; E238-K273 IonicContact OE1-NZ 3.62Å; E238-K273 PolarHBondContact OE1-NZ 3.38Å; E238-K273 IonicContact OE2-NZ 2.99Å; E238-K273 PolarHBondContact OE2-NZ 3.24Å; F242-K273 VanDerWaalsContact CE2-NZ 3.33Å; L259-K273 HydrophobicContact CD1-CD 4.05Å; Y269-K273 HydrophobicContact CE1-CB 4.3Å; Y269-K273 HydrophobicContact CE1-CD 3.94Å; Y269-K273 HydrophobicContact CE1-CG 4.32Å; Y269-K273 WeakPolarHBondContact O-CA 2.97Å; Y269-K273 WeakPolarHBondContact O-CB 3.25Å; Y269-K273 PolarHBondContact O-N 2.88Å; E271-K273 PolarHBondContact O-N 3.23Å; K273-W275 VanDerWaalsContact C-N 3.33Å; K273-W275 PolarHBondContact O-N 3.39Å; K273-W276 PolarHBondContact O-N 2.96Å; K273-L277 HydrophobicContact CD-CD1 4.44Å; K273-L277 HydrophobicContact CG-CD1 3.77Å; K273-L277 HydrophobicContact CG-CG 4.23Å; K273-L277 WeakPolarHBondContact O-CB 3.07Å; K273-L277 VanDerWaalsContact O-CG 3.22Å; K273-L277 WeakPolarHBondContact O-CG 3.22Å; K273-L277 PolarHBondContact O-N 3.47Å
274D91.7Very high91.7Very high33 Ų3362.4 Ų62.418%0.17630%0.298CS..Hα-helixtrans-67.2-36.8-173.4-67.5-41.4000112A272 F278 I345A272-D274 PolarHBondContact O-N 3.4Å; D274-F278 VanDerWaalsContact O-CB 3.31Å; D274-F278 WeakPolarHBondContact O-CB 3.39Å; D274-F278 PolarHBondContact O-N 3.11Å; D274-I345 HydrophobicContact CB-CD1 4.01Å
275W93.3Very high91.7Very high126 Ų12656.1 Ų56.148%0.47726%0.264SS..Hα-helixtrans-68.6-43.4174.3-69118.3000112A272 K273 F278 G279 I345 M349A272-W275 PolarHBondContact O-N 3.42Å; K273-W275 VanDerWaalsContact C-N 3.33Å; K273-W275 PolarHBondContact O-N 3.39Å; W275-F278 PolarHBondContact O-N 3.43Å; W275-G279 PolarHBondContact O-N 3.32Å; W275-I345 HydrophobicContact CD2-CD1 4.18Å; W275-I345 HydrophobicContact CE3-CD1 4.07Å; W275-I345 HydrophobicContact CH2-CG2 4.44Å; W275-I345 HydrophobicContact CZ3-CD1 4.27Å; W275-M349 HydrophobicContact CZ2-SD 4Å
276W94Very high91.8Very high101 Ų10152.9 Ų52.938%0.38325%0.252SS..Hα-helixtrans-59.5-48.2174.3165.4-107.7000111.2L234 A272 K273 F278 G279 F280 Y281L234-W276 HydrophobicContact CD1-CZ2 4.41Å; L234-W276 HydrophobicContact CD2-CH2 4.24Å; L234-W276 HydrophobicContact CD2-CZ2 3.76Å; A272-W276 WeakPolarHBondContact O-CB 3.4Å; A272-W276 PolarHBondContact O-N 3.42Å; K273-W276 PolarHBondContact O-N 2.96Å; W276-F278 PolarHBondContact O-N 3.3Å; W276-G279 PolarHBondContact O-N 2.87Å; W276-F280 HydrophobicContact CD2-CB 4.25Å; W276-F280 HydrophobicContact CE3-CB 4.22Å; W276-F280 HydrophobicContact CH2-CB 3.78Å; W276-F280 AromaticContact CH2-CD2 3.6Å; W276-F280 HydrophobicContact CH2-CD2 3.6Å; W276-F280 HydrophobicContact CH2-CE2 4.35Å; W276-F280 AromaticContact CH2-CG 3.7Å; W276-F280 HydrophobicContact CH2-CG 3.7Å; W276-F280 HydrophobicContact CZ2-CB 3.78Å; W276-F280 HydrophobicContact CZ2-CD1 4.15Å; W276-F280 HydrophobicContact CZ2-CD2 4.05Å; W276-F280 AromaticContact CZ2-CG 3.71Å; W276-F280 HydrophobicContact CZ2-CG 3.71Å; W276-F280 HydrophobicContact CZ3-CB 4.01Å; W276-F280 HydrophobicContact CZ3-CD2 4.28Å; W276-F280 HydrophobicContact CZ3-CG 4.37Å; W276-F280 WeakPolarHBondContact O-CB 3.34Å; W276-F280 PolarHBondContact O-N 2.73Å; W276-Y281 AromaticContact NE1-CE2 3.94Å
277L93.2Very high92Very high2 Ų256 Ų561%0.0127%0.268CS..Iπ-helixtrans-62.2-43.7178.7-72.8177.1000111.4K184 K273 Y281 F282 H341K184-L277 HydrophobicContact CD-CD2 4.09Å; K273-L277 HydrophobicContact CD-CD1 4.44Å; K273-L277 HydrophobicContact CG-CD1 3.77Å; K273-L277 HydrophobicContact CG-CG 4.23Å; K273-L277 WeakPolarHBondContact O-CB 3.07Å; K273-L277 VanDerWaalsContact O-CG 3.22Å; K273-L277 WeakPolarHBondContact O-CG 3.22Å; K273-L277 PolarHBondContact O-N 3.47Å; L277-Y281 HydrophobicContact CD2-CD2 3.56Å; L277-Y281 HydrophobicContact CD2-CE2 3.58Å; L277-Y281 HydrophobicContact CD2-CG 4.41Å; L277-Y281 WeakPolarHBondContact O-CA 3.27Å; L277-Y281 VanDerWaalsContact O-CB 3.3Å; L277-Y281 WeakPolarHBondContact O-CB 3.3Å; L277-Y281 PolarHBondContact O-N 2.94Å; L277-F282 PolarHBondContact O-N 3.16Å; L277-H341 PolarHBondContact O-CE1 2.95Å
278F94.1Very high92.1Very high62 Ų6249 Ų4927%0.27225%0.245SC..Iπ-helixtrans-64.9-46.8175.8179.6-109.9000112D274 W275 W276 F282 C283 H341D274-F278 VanDerWaalsContact O-CB 3.31Å; D274-F278 WeakPolarHBondContact O-CB 3.39Å; D274-F278 PolarHBondContact O-N 3.11Å; W275-F278 PolarHBondContact O-N 3.43Å; W276-F278 PolarHBondContact O-N 3.3Å; F278-F282 HydrophobicContact CD2-CB 4.17Å; F278-F282 AromaticContact CD2-CD1 3.78Å; F278-F282 HydrophobicContact CD2-CD1 3.78Å; F278-F282 HydrophobicContact CD2-CG 4.21Å; F278-F282 AromaticContact CE2-CD1 3.37Å; F278-F282 HydrophobicContact CE2-CD1 3.37Å; F278-F282 AromaticContact CE2-CE1 3.75Å; F278-F282 HydrophobicContact CE2-CE1 3.75Å; F278-F282 HydrophobicContact CE2-CG 4.21Å; F278-F282 HydrophobicContact CZ-CD1 4.14Å; F278-F282 HydrophobicContact CZ-CE1 4.4Å; F278-F282 WeakPolarHBondContact O-CA 3.46Å; F278-F282 VanDerWaalsContact O-CB 3.24Å; F278-F282 WeakPolarHBondContact O-CB 3.37Å; F278-F282 PolarHBondContact O-N 2.89Å; F278-C283 PolarHBondContact O-N 3.31Å; F278-C283 PolarHBondContact O-SG 3.28Å; F278-H341 HydrophobicContact CD2-CB 3.91Å
279G94.6Very high91.9Very high30 Ų3042.5 Ų42.531%0.30922%0.217SC..Iπ-helixtrans-62.7-57.6179.400000112.3W275 W276 C283 V284W275-G279 PolarHBondContact O-N 3.32Å; W276-G279 PolarHBondContact O-N 2.87Å; G279-C283 VanDerWaalsContact O-CB 3.3Å; G279-C283 WeakPolarHBondContact O-CB 3.22Å; G279-C283 PolarHBondContact O-N 3.4Å; G279-V284 PolarHBondContact O-N 2.58Å; G279-V284 VanDerWaalsContact O-N 3.11Å
280F93.3Very high91.7Very high37 Ų3744 Ų4416%0.16223%0.233CC..Iπ-helixtrans-77.8-49.8-172.6-173.3-91.5000113.1L192 L234 W276 V284L192-F280 HydrophobicContact CD2-CZ 4.2Å; L234-F280 HydrophobicContact CD1-CD1 3.97Å; L234-F280 HydrophobicContact CD1-CE1 3.22Å; L234-F280 HydrophobicContact CD1-CE2 4.04Å; L234-F280 HydrophobicContact CD1-CZ 3.25Å; W276-F280 HydrophobicContact CD2-CB 4.25Å; W276-F280 HydrophobicContact CE3-CB 4.22Å; W276-F280 HydrophobicContact CH2-CB 3.78Å; W276-F280 AromaticContact CH2-CD2 3.6Å; W276-F280 HydrophobicContact CH2-CD2 3.6Å; W276-F280 HydrophobicContact CH2-CE2 4.35Å; W276-F280 AromaticContact CH2-CG 3.7Å; W276-F280 HydrophobicContact CH2-CG 3.7Å; W276-F280 HydrophobicContact CZ2-CB 3.78Å; W276-F280 HydrophobicContact CZ2-CD1 4.15Å; W276-F280 HydrophobicContact CZ2-CD2 4.05Å; W276-F280 AromaticContact CZ2-CG 3.71Å; W276-F280 HydrophobicContact CZ2-CG 3.71Å; W276-F280 HydrophobicContact CZ3-CB 4.01Å; W276-F280 HydrophobicContact CZ3-CD2 4.28Å; W276-F280 HydrophobicContact CZ3-CG 4.37Å; W276-F280 WeakPolarHBondContact O-CB 3.34Å; W276-F280 PolarHBondContact O-N 2.73Å; F280-V284 HydrophobicContact CD2-CG2 4.4Å; F280-V284 WeakPolarHBondContact O-CB 3.29Å
281Y93.2Very high91.9Very high3 Ų346.3 Ų46.31%0.01224%0.243CC..Iπ-helixtrans-84.1-21.9-173.5-66.3-97.6000112.8K184 V187 G188 V191 W276 L277 P285 F333K184-Y281 WeakPolarHBondContact O-CE1 3.45Å; V187-Y281 HydrophobicContact CB-CD1 4.18Å; V187-Y281 HydrophobicContact CB-CE1 4.36Å; V187-Y281 HydrophobicContact CG1-CD1 3.69Å; V187-Y281 HydrophobicContact CG1-CE1 4.36Å; V187-Y281 HydrophobicContact CG1-CG 4.43Å; G188-Y281 VanDerWaalsContact CA-CE1 3.46Å; V191-Y281 HydrophobicContact CG2-CD1 4.47Å; V191-Y281 VanDerWaalsContact CG2-O 3.23Å; V191-Y281 WeakPolarHBondContact CG2-O 3.36Å; W276-Y281 AromaticContact NE1-CE2 3.94Å; L277-Y281 HydrophobicContact CD2-CD2 3.56Å; L277-Y281 HydrophobicContact CD2-CE2 3.58Å; L277-Y281 HydrophobicContact CD2-CG 4.41Å; L277-Y281 WeakPolarHBondContact O-CA 3.27Å; L277-Y281 VanDerWaalsContact O-CB 3.3Å; L277-Y281 WeakPolarHBondContact O-CB 3.3Å; L277-Y281 PolarHBondContact O-N 2.94Å; Y281-P285 WeakPolarHBondContact O-CG 3.31Å; Y281-F333 VanDerWaalsContact O-CZ 3.29Å; Y281-F333 WeakPolarHBondContact O-CZ 3.38Å
282F92.9Very high91.8Very high16 Ų1643.3 Ų43.37%0.0723%0.228CC..Iπ-helixtrans-108.5-52.9179.8-175.6-95.3000113.1L277 F278 P285 L286 F333 A334 W337 F338 H341L277-F282 PolarHBondContact O-N 3.16Å; F278-F282 HydrophobicContact CD2-CB 4.17Å; F278-F282 AromaticContact CD2-CD1 3.78Å; F278-F282 HydrophobicContact CD2-CD1 3.78Å; F278-F282 HydrophobicContact CD2-CG 4.21Å; F278-F282 AromaticContact CE2-CD1 3.37Å; F278-F282 HydrophobicContact CE2-CD1 3.37Å; F278-F282 AromaticContact CE2-CE1 3.75Å; F278-F282 HydrophobicContact CE2-CE1 3.75Å; F278-F282 HydrophobicContact CE2-CG 4.21Å; F278-F282 HydrophobicContact CZ-CD1 4.14Å; F278-F282 HydrophobicContact CZ-CE1 4.4Å; F278-F282 WeakPolarHBondContact O-CA 3.46Å; F278-F282 VanDerWaalsContact O-CB 3.24Å; F278-F282 WeakPolarHBondContact O-CB 3.37Å; F278-F282 PolarHBondContact O-N 2.89Å; F282-P285 WeakPolarHBondContact O-CD 3.04Å; F282-P285 VanDerWaalsContact O-CG 3.32Å; F282-P285 WeakPolarHBondContact O-CG 3.24Å; F282-L286 HydrophobicContact CD1-CD1 3.91Å; F282-L286 HydrophobicContact CE1-CD1 3.53Å; F282-L286 HydrophobicContact CE2-CD1 4.24Å; F282-L286 HydrophobicContact CG-CD1 4.41Å; F282-L286 HydrophobicContact CZ-CD1 3.72Å; F282-L286 WeakPolarHBondContact O-CD1 3.36Å; F282-L286 VanDerWaalsContact O-CG 3.26Å; F282-L286 WeakPolarHBondContact O-CG 3.13Å; F282-F333 HydrophobicContact CD2-CE1 4.42Å; F282-A334 HydrophobicContact CE2-CB 4.49Å; F282-W337 HydrophobicContact CD2-CB 3.98Å; F282-W337 HydrophobicContact CE2-CB 4.23Å; F282-F338 HydrophobicContact CE1-CD2 4.45Å; F282-F338 HydrophobicContact CE2-CB 3.98Å; F282-F338 HydrophobicContact CZ-CB 3.97Å; F282-F338 AromaticContact CZ-CD2 3.94Å; F282-F338 HydrophobicContact CZ-CD2 3.94Å; F282-F338 HydrophobicContact CZ-CG 4.46Å; F282-H341 AromaticContact CD2-CD2 3.81Å
283C94.3Very high91.4Very high34 Ų3445.2 Ų45.223%0.2323%0.229CC..Iπ-helixtrans-73-43-174.7-61.80000113.5F278 G279 L286 I287F278-C283 PolarHBondContact O-N 3.31Å; F278-C283 PolarHBondContact O-SG 3.28Å; G279-C283 VanDerWaalsContact O-CB 3.3Å; G279-C283 WeakPolarHBondContact O-CB 3.22Å; G279-C283 PolarHBondContact O-N 3.4Å; C283-L286 PolarHBondContact O-N 3.36Å; C283-I287 HydrophobicContact CB-CD1 4.2Å; C283-I287 WeakPolarHBondContact O-CB 3.32Å; C283-I287 VanDerWaalsContact O-CG1 3.29Å; C283-I287 WeakPolarHBondContact O-CG1 3.33Å; C283-I287 PolarHBondContact O-N 3.22Å
284V91.8Very high91Very high59 Ų5948.3 Ų48.336%0.35825%0.249SC..Hα-helixtrans-54.8-51.2-179.7173.40000113.3G279 F280 L286 I287 C288G279-V284 PolarHBondContact O-N 2.58Å; G279-V284 VanDerWaalsContact O-N 3.11Å; F280-V284 HydrophobicContact CD2-CG2 4.4Å; F280-V284 WeakPolarHBondContact O-CB 3.29Å; V284-L286 VanDerWaalsContact C-N 3.29Å; V284-L286 PolarHBondContact O-N 2.98Å; V284-I287 PolarHBondContact O-N 3.39Å; V284-C288 WeakPolarHBondContact O-CB 3.19Å; V284-C288 PolarHBondContact O-N 3.13Å
285P89.6Confident90.7Very high0 Ų050.2 Ų50.20%026%0.259CS..Hα-helixtrans-63.1-34.4179.621.1-31.5000113.4V191 Y281 F282 T289 F333V191-P285 HydrophobicContact CB-CG 4.46Å; V191-P285 HydrophobicContact CG1-CB 3.92Å; V191-P285 HydrophobicContact CG1-CG 3.63Å; V191-P285 HydrophobicContact CG2-CG 4.21Å; Y281-P285 WeakPolarHBondContact O-CG 3.31Å; F282-P285 WeakPolarHBondContact O-CD 3.04Å; F282-P285 VanDerWaalsContact O-CG 3.32Å; F282-P285 WeakPolarHBondContact O-CG 3.24Å; P285-T289 VanDerWaalsContact O-CB 3.25Å; P285-T289 WeakPolarHBondContact O-CB 3.33Å; P285-T289 PolarHBondContact O-N 3.46Å; P285-T289 PolarHBondContact O-OG1 2.94Å; P285-F333 HydrophobicContact CB-CE1 4.37Å; P285-F333 HydrophobicContact CG-CD1 4.47Å; P285-F333 HydrophobicContact CG-CE1 3.67Å; P285-F333 HydrophobicContact CG-CZ 4.12Å
286L91.4Very high90Very high47 Ų4744.6 Ų44.625%0.24624%0.238CC..Hα-helixtrans-68.1-48.4177.1-62.4176.7000111.2F282 C283 V284 T289 A290 V330 A334F282-L286 HydrophobicContact CD1-CD1 3.91Å; F282-L286 HydrophobicContact CE1-CD1 3.53Å; F282-L286 HydrophobicContact CE2-CD1 4.24Å; F282-L286 HydrophobicContact CG-CD1 4.41Å; F282-L286 HydrophobicContact CZ-CD1 3.72Å; F282-L286 WeakPolarHBondContact O-CD1 3.36Å; F282-L286 VanDerWaalsContact O-CG 3.26Å; F282-L286 WeakPolarHBondContact O-CG 3.13Å; C283-L286 PolarHBondContact O-N 3.36Å; V284-L286 VanDerWaalsContact C-N 3.29Å; V284-L286 PolarHBondContact O-N 2.98Å; L286-T289 PolarHBondContact O-N 3.33Å; L286-A290 WeakPolarHBondContact O-CB 3.38Å; L286-A290 PolarHBondContact O-N 3.48Å; L286-V330 HydrophobicContact CD2-CG1 3.68Å; L286-A334 HydrophobicContact CD1-CB 4.44Å; L286-A334 HydrophobicContact CD2-CB 3.7Å
287I93Very high89.2Confident99 Ų9942.2 Ų42.251%0.50824%0.235SC..Hα-helixtrans-64.4-48179.1-67.2166.6000110.1C283 V284 T289 A290 I291C283-I287 HydrophobicContact CB-CD1 4.2Å; C283-I287 WeakPolarHBondContact O-CB 3.32Å; C283-I287 VanDerWaalsContact O-CG1 3.29Å; C283-I287 WeakPolarHBondContact O-CG1 3.33Å; C283-I287 PolarHBondContact O-N 3.22Å; V284-I287 PolarHBondContact O-N 3.39Å; I287-T289 PolarHBondContact O-N 2.86Å; I287-A290 PolarHBondContact O-N 3.42Å; I287-I291 HydrophobicContact CG2-CD1 3.64Å; I287-I291 HydrophobicContact CG2-CG1 4.34Å; I287-I291 WeakPolarHBondContact O-CB 3.47Å; I287-I291 VanDerWaalsContact O-CG1 3.25Å; I287-I291 WeakPolarHBondContact O-CG1 3.27Å; I287-I291 PolarHBondContact O-N 2.82Å
288C91.2Very high88.6Confident23 Ų2345.4 Ų45.416%0.15526%0.257CS..Hα-helixtrans-55.4-51.2177.7-179.90000110.9C195 V284 A290 I291 F292C195-C288 VanDerWaalsContact SG-SG 3.66Å; V284-C288 WeakPolarHBondContact O-CB 3.19Å; V284-C288 PolarHBondContact O-N 3.13Å; C288-A290 PolarHBondContact O-N 3.47Å; C288-I291 PolarHBondContact O-N 3.36Å; C288-F292 WeakPolarHBondContact O-CD2 3Å; C288-F292 PolarHBondContact O-N 3.04Å; C288-F292 VanDerWaalsContact SG-CD2 3.59Å; C288-F292 VanDerWaalsContact SG-CE2 3.54Å
289T86.9Confident87.8Confident4 Ų445 Ų453%0.02526%0.256CS..Hα-helixtrans-65.8-41.7179.3-56.10000111.8S198 P285 L286 I287 I291 F292 Y293 V330S198-T289 PolarHBondContact OG-OG1 3.22Å; P285-T289 VanDerWaalsContact O-CB 3.25Å; P285-T289 WeakPolarHBondContact O-CB 3.33Å; P285-T289 PolarHBondContact O-N 3.46Å; P285-T289 PolarHBondContact O-OG1 2.94Å; L286-T289 PolarHBondContact O-N 3.33Å; I287-T289 PolarHBondContact O-N 2.86Å; T289-I291 VanDerWaalsContact C-N 3.33Å; T289-I291 PolarHBondContact O-N 3.44Å; T289-F292 PolarHBondContact O-N 2.03Å; T289-Y293 WeakPolarHBondContact O-CB 3.29Å; T289-Y293 PolarHBondContact O-N 2.95Å; T289-V330 HydrophobicContact CG2-CB 3.9Å; T289-V330 HydrophobicContact CG2-CG1 3.97Å; T289-V330 HydrophobicContact CG2-CG2 3.71Å; T289-V330 WeakPolarHBondContact OG1-CG2 3.28Å
290A88.3Confident86.5Confident49 Ų4945.5 Ų45.541%0.40525%0.251SS..Hα-helixtrans-60-44.2177.600000111.4L286 I287 C288 T294L286-A290 WeakPolarHBondContact O-CB 3.38Å; L286-A290 PolarHBondContact O-N 3.48Å; I287-A290 PolarHBondContact O-N 3.42Å; C288-A290 PolarHBondContact O-N 3.47Å; A290-T294 VanDerWaalsContact O-CB 3.27Å; A290-T294 WeakPolarHBondContact O-CB 3.39Å; A290-T294 PolarHBondContact O-N 2.97Å; A290-T294 PolarHBondContact O-OG1 2.89Å
291I90.6Very high85.4Confident87 Ų8747.5 Ų47.545%0.44626%0.262SS..Hα-helixtrans-61.8-56.4176.2-68.2168000110.2I287 C288 T289 Y293 T294 L295I287-I291 HydrophobicContact CG2-CD1 3.64Å; I287-I291 HydrophobicContact CG2-CG1 4.34Å; I287-I291 WeakPolarHBondContact O-CB 3.47Å; I287-I291 VanDerWaalsContact O-CG1 3.25Å; I287-I291 WeakPolarHBondContact O-CG1 3.27Å; I287-I291 PolarHBondContact O-N 2.82Å; C288-I291 PolarHBondContact O-N 3.36Å; T289-I291 VanDerWaalsContact C-N 3.33Å; T289-I291 PolarHBondContact O-N 3.44Å; I291-Y293 VanDerWaalsContact C-N 3.32Å; I291-Y293 PolarHBondContact O-N 2.85Å; I291-T294 PolarHBondContact O-N 3.33Å; I291-T294 VanDerWaalsContact O-N 3.15Å; I291-L295 HydrophobicContact CG2-CD1 3.88Å; I291-L295 HydrophobicContact CG2-CG 4.31Å; I291-L295 WeakPolarHBondContact O-CG 3.49Å; I291-L295 PolarHBondContact O-N 3.05Å
292F86.2Confident84.3Confident50 Ų5052.7 Ų52.722%0.21929%0.29CS..Hα-helixtrans-65.7-33.4-176.4-75.2-63000113.3V199 Y202 C288 T289 L295 M296V199-F292 HydrophobicContact CG2-CD2 3.83Å; V199-F292 HydrophobicContact CG2-CE1 4.16Å; V199-F292 HydrophobicContact CG2-CE2 3.33Å; V199-F292 HydrophobicContact CG2-CG 4.47Å; V199-F292 HydrophobicContact CG2-CZ 3.53Å; Y202-F292 AromaticContact CD1-CD1 3.69Å; Y202-F292 HydrophobicContact CD1-CD1 3.69Å; Y202-F292 AromaticContact CD1-CE1 3.94Å; Y202-F292 HydrophobicContact CD1-CE1 3.94Å; Y202-F292 HydrophobicContact CE1-CD1 4.48Å; Y202-F292 HydrophobicContact CE1-CE1 4.5Å; Y202-F292 AromaticContact CG-CD1 3.75Å; Y202-F292 HydrophobicContact CG-CD1 3.75Å; Y202-F292 HydrophobicContact CG-CE1 4.46Å; C288-F292 WeakPolarHBondContact O-CD2 3Å; C288-F292 PolarHBondContact O-N 3.04Å; C288-F292 VanDerWaalsContact SG-CD2 3.59Å; C288-F292 VanDerWaalsContact SG-CE2 3.54Å; T289-F292 PolarHBondContact O-N 2.03Å; F292-L295 HydrophobicContact CD1-CD1 4.35Å; F292-M296 WeakPolarHBondContact O-CB 2.99Å; F292-M296 PolarHBondContact O-N 2.66Å
293Y83.6Confident82.9Confident71 Ų7156.1 Ų56.128%0.27831%0.307SS..Hα-helixtrans-69.1-39.3174.2-175.6-98000111.9T289 I291 T297 F327T289-Y293 WeakPolarHBondContact O-CB 3.29Å; T289-Y293 PolarHBondContact O-N 2.95Å; I291-Y293 VanDerWaalsContact C-N 3.32Å; I291-Y293 PolarHBondContact O-N 2.85Å; Y293-T297 WeakPolarHBondContact O-CB 3.35Å; Y293-T297 PolarHBondContact O-N 2.88Å; Y293-T297 PolarHBondContact O-OG1 3.07Å; Y293-F327 HydrophobicContact CD1-CD2 4.3Å; Y293-F327 HydrophobicContact CD2-CB 4.06Å; Y293-F327 HydrophobicContact CD2-CD2 4.43Å; Y293-F327 HydrophobicContact CD2-CG 4.49Å; Y293-F327 HydrophobicContact CE2-CB 3.99Å; Y293-F327 HydrophobicContact CE2-CG 4.37Å; Y293-F327 HydrophobicContact CG-CD2 4.25Å
294T84.9Confident81.1Confident81 Ų8163 Ų6350%0.49733%0.328SS..Hα-helixtrans-64.4-50.8174.6-57.80000110.1A290 I291 M296 T297 C298A290-T294 VanDerWaalsContact O-CB 3.27Å; A290-T294 WeakPolarHBondContact O-CB 3.39Å; A290-T294 PolarHBondContact O-N 2.97Å; A290-T294 PolarHBondContact O-OG1 2.89Å; I291-T294 PolarHBondContact O-N 3.33Å; I291-T294 VanDerWaalsContact O-N 3.15Å; T294-M296 VanDerWaalsContact C-N 3.31Å; T294-M296 PolarHBondContact O-N 3.32Å; T294-T297 PolarHBondContact O-N 3.4Å; T294-T297 VanDerWaalsContact O-N 3.09Å; T294-C298 WeakPolarHBondContact O-CB 3.37Å; T294-C298 PolarHBondContact O-N 3.24Å; T294-C298 PolarHBondContact O-SG 2.88Å
295L84.6Confident79.3Confident73 Ų7367 Ų6738%0.38235%0.347SS..Hα-helixtrans-57.1-44.3176.5-68.6176.5000111.8Y202 I291 F292 T297 C298 E299Y202-L295 HydrophobicContact CD2-CB 3.87Å; Y202-L295 HydrophobicContact CE2-CB 3.56Å; Y202-L295 HydrophobicContact CE2-CD1 4.49Å; I291-L295 HydrophobicContact CG2-CD1 3.88Å; I291-L295 HydrophobicContact CG2-CG 4.31Å; I291-L295 WeakPolarHBondContact O-CG 3.49Å; I291-L295 PolarHBondContact O-N 3.05Å; F292-L295 HydrophobicContact CD1-CD1 4.35Å; L295-T297 PolarHBondContact O-N 2.84Å; L295-C298 PolarHBondContact O-N 3.46Å; L295-E299 WeakPolarHBondContact O-CB 3.41Å; L295-E299 PolarHBondContact O-N 3.12Å
296M78.8Confident77.7Confident8 Ų869 Ų694%0.03937%0.368CS..Hα-helixtrans-60.2-45.5175.3177175.9168.600111.8Y202 V205 F292 T294 E299 M300 A323Y202-M296 HydrophobicContact CD2-CB 4.26Å; V205-M296 HydrophobicContact CB-CE 4.42Å; V205-M296 HydrophobicContact CB-CG 4.19Å; V205-M296 HydrophobicContact CG1-CE 4.44Å; V205-M296 HydrophobicContact CG1-CG 4.05Å; V205-M296 HydrophobicContact CG2-CE 3.4Å; V205-M296 VanDerWaalsContact CG2-CE 3.4Å; V205-M296 HydrophobicContact CG2-CG 4.06Å; V205-M296 HydrophobicContact CG2-SD 3.83Å; F292-M296 WeakPolarHBondContact O-CB 2.99Å; F292-M296 PolarHBondContact O-N 2.66Å; T294-M296 VanDerWaalsContact C-N 3.31Å; T294-M296 PolarHBondContact O-N 3.32Å; M296-E299 PolarHBondContact O-N 3.32Å; M296-M300 HydrophobicContact CE-SD 3.61Å; M296-M300 HydrophobicContact CG-SD 4.28Å; M296-M300 VanDerWaalsContact O-CG 3.26Å; M296-M300 WeakPolarHBondContact O-CG 3.35Å; M296-M300 PolarHBondContact O-N 3.35Å; M296-A323 HydrophobicContact CE-CB 3.18Å; M296-A323 HydrophobicContact SD-CB 3.26Å; M296-A323 WeakPolarHBondContact SD-CB 3.05Å
297T77.1Confident75.7Confident51 Ų5173.5 Ų73.531%0.31340%0.398SS..Hα-helixtrans-66.9-41-179.5-57.60000111.1Y293 T294 L295 M300 L301Y293-T297 WeakPolarHBondContact O-CB 3.35Å; Y293-T297 PolarHBondContact O-N 2.88Å; Y293-T297 PolarHBondContact O-OG1 3.07Å; T294-T297 PolarHBondContact O-N 3.4Å; T294-T297 VanDerWaalsContact O-N 3.09Å; L295-T297 PolarHBondContact O-N 2.84Å; T297-M300 PolarHBondContact O-N 3.36Å; T297-L301 HydrophobicContact CG2-CD1 4.11Å; T297-L301 WeakPolarHBondContact O-CB 3.47Å; T297-L301 VanDerWaalsContact O-CG 3.26Å; T297-L301 WeakPolarHBondContact O-CG 3.41Å; T297-L301 PolarHBondContact O-N 3.29Å
298C80.9Confident73.8Confident69 Ų6974.4 Ų74.447%0.46640%0.403SS..Hα-helixtrans-60.7-47174.5-69.90000111.6T294 L295 M300 L301 N302T294-C298 WeakPolarHBondContact O-CB 3.37Å; T294-C298 PolarHBondContact O-N 3.24Å; T294-C298 PolarHBondContact O-SG 2.88Å; L295-C298 PolarHBondContact O-N 3.46Å; C298-M300 VanDerWaalsContact C-N 3.32Å; C298-M300 PolarHBondContact O-N 2.96Å; C298-L301 PolarHBondContact O-N 3.45Å; C298-L301 VanDerWaalsContact O-N 3.11Å; C298-N302 WeakPolarHBondContact O-CB 3.22Å; C298-N302 PolarHBondContact O-N 3.23Å
299E76.9Confident72.1Confident55 Ų5583.3 Ų83.326%0.25743%0.433SS..Hα-helixtrans-59.1-44.9178-167.161.2-152.900111.3L295 M296 L301 N302 H303L295-E299 WeakPolarHBondContact O-CB 3.41Å; L295-E299 PolarHBondContact O-N 3.12Å; M296-E299 PolarHBondContact O-N 3.32Å; E299-L301 VanDerWaalsContact C-N 3.31Å; E299-L301 PolarHBondContact O-N 3.42Å; E299-N302 PolarHBondContact O-N 3.47Å; E299-H303 PolarHBondContact O-CD2 2.99Å; E299-H303 PolarHBondContact O-N 2.88Å; E299-H303 VanDerWaalsContact O-N 3.16Å; E299-H303 IonicContact OE1-CD2 3.44Å; E299-H303 PolarHBondContact OE1-CD2 3.35Å; E299-H303 IonicContact OE1-NE2 3.23Å; E299-H303 PolarHBondContact OE1-NE2 3.38Å
300M67.9Low70.5Confident39 Ų3989.7 Ų89.719%0.19247%0.466CS..Hα-helixtrans-64.9-33.1176.6-70.4-176.271.800113.3V205 M296 T297 C298 L316 R320V205-M300 HydrophobicContact CG1-CG 3.84Å; V205-M300 HydrophobicContact CG1-SD 4.46Å; M296-M300 HydrophobicContact CE-SD 3.61Å; M296-M300 HydrophobicContact CG-SD 4.28Å; M296-M300 VanDerWaalsContact O-CG 3.26Å; M296-M300 WeakPolarHBondContact O-CG 3.35Å; M296-M300 PolarHBondContact O-N 3.35Å; T297-M300 PolarHBondContact O-N 3.36Å; C298-M300 VanDerWaalsContact C-N 3.32Å; C298-M300 PolarHBondContact O-N 2.96Å; M300-L316 HydrophobicContact CE-CB 4.06Å; M300-L316 HydrophobicContact CE-CD2 4.31Å; M300-R320 HydrophobicContact CE-CB 4.22Å
301L70.3Confident68.7Low79 Ų7991.4 Ų91.441%0.41448%0.48SS..Hα-helixtrans-75-37.2176.9-74.4170.8000111.9T297 C298 E299 R304T297-L301 HydrophobicContact CG2-CD1 4.11Å; T297-L301 WeakPolarHBondContact O-CB 3.47Å; T297-L301 VanDerWaalsContact O-CG 3.26Å; T297-L301 WeakPolarHBondContact O-CG 3.41Å; T297-L301 PolarHBondContact O-N 3.29Å; C298-L301 PolarHBondContact O-N 3.45Å; C298-L301 VanDerWaalsContact O-N 3.11Å; E299-L301 VanDerWaalsContact C-N 3.31Å; E299-L301 PolarHBondContact O-N 3.42Å; L301-R304 WeakPolarHBondContact O-CB 3.47Å; L301-R304 PolarHBondContact O-N 3.35Å; L301-R304 VanDerWaalsContact O-N 3.15Å
302N70.2Confident67Low112 Ų11288.7 Ų88.760%0.59947%0.466SS*.Hα-helixtrans-66-42179.1-160.721000111.2C298 E299 R304 N305C298-N302 WeakPolarHBondContact O-CB 3.22Å; C298-N302 PolarHBondContact O-N 3.23Å; E299-N302 PolarHBondContact O-N 3.47Å; N302-R304 PolarHBondContact O-N 3.4Å; N302-N305 PolarHBondContact O-N 3.28Å
303H62.4Low65.6Low88 Ų8889 Ų8941%0.40747%0.474SS..G310 helixtrans-69-10.6173.9-81.6-73.6000114.6E299 N305E299-H303 PolarHBondContact O-CD2 2.99Å; E299-H303 PolarHBondContact O-N 2.88Å; E299-H303 VanDerWaalsContact O-N 3.16Å; E299-H303 IonicContact OE1-CD2 3.44Å; E299-H303 PolarHBondContact OE1-CD2 3.35Å; E299-H303 IonicContact OE1-NE2 3.23Å; E299-H303 PolarHBondContact OE1-NE2 3.38Å; H303-N305 PolarHBondContact O-N 3.35Å
304R57.3Low64.4Low180 Ų18090.7 Ų90.768%0.67949%0.485SS*.G310 helixtrans-73.2-15.8175.4-160.5169.968.1175.72.6112.9L301 N302L301-R304 WeakPolarHBondContact O-CB 3.47Å; L301-R304 PolarHBondContact O-N 3.35Å; L301-R304 VanDerWaalsContact O-N 3.15Å; N302-R304 PolarHBondContact O-N 3.4Å
305N52.3Low63.3Low141 Ų14192.8 Ų92.875%0.75449%0.489SS*.G310 helixtrans-86.7-2.4179.1-69.2-14.9000113.8N302 H303N302-N305 PolarHBondContact O-N 3.28Å; H303-N305 PolarHBondContact O-N 3.35Å
306G56.9Low62.2Low44 Ų4490.8 Ų90.845%0.45448%0.478SS..SBendtrans-103.9140.8176.700000113.9L308G306-L308 PolarHBondContact O-N 2.84Å
307T48.8Very low61.6Low140 Ų14095.7 Ų95.786%0.85950%0.5SS*.SBendtrans-68.949.1-174.7-37.70000115
308L53Low61Low118 Ų11899.7 Ų99.762%0.61852%0.515SS*.  trans-122.365.9175.9-162.869.1000110.4W208 G306 L312W208-L308 HydrophobicContact CH2-CD2 4.39Å; G306-L308 PolarHBondContact O-N 2.84Å; L308-L312 HydrophobicContact CD2-CD2 4.39Å
309R55.4Low60.2Low210 Ų210100.2 Ų100.279%0.79251%0.507SS*.  trans-88.1-10.6-147.2-102.2-175.6178.6-178.60.5119.1
310I53.5Low59.7Low139 Ų139104.3 Ų104.371%0.71352%0.52SS*.SBendtrans-127.9-55.5-165.2-54.4178.3000114.3L312 S313I310-L312 PolarHBondContact O-N 3.18Å; I310-S313 WeakPolarHBondContact O-CB 3.33Å; I310-S313 PolarHBondContact O-N 3.26Å; I310-S313 PolarHBondContact O-OG 3Å
311A51.5Low59.7Low85 Ų85107 Ų10770%0.70253%0.532SS*.Hα-helixtrans-70.1-31.4179.200000113.3S313A311-S313 VanDerWaalsContact C-N 3.26Å; A311-S313 PolarHBondContact O-N 3.21Å
312L54.4Low59.4Low30 Ų30105.8 Ų105.816%0.15753%0.528CS..Hα-helixtrans-67.1-28.2175.5-179.656.4000112.4W208 L308 I310 E314 H315 L316W208-L312 HydrophobicContact CH2-CD1 3.14Å; W208-L312 HydrophobicContact CH2-CD2 3.58Å; W208-L312 HydrophobicContact CH2-CG 3.9Å; W208-L312 HydrophobicContact CZ2-CD1 3.31Å; W208-L312 HydrophobicContact CZ2-CD2 3.62Å; W208-L312 HydrophobicContact CZ2-CG 4.05Å; W208-L312 HydrophobicContact CZ3-CD1 4.09Å; L308-L312 HydrophobicContact CD2-CD2 4.39Å; I310-L312 PolarHBondContact O-N 3.18Å; L312-E314 PolarHBondContact O-N 2.96Å; L312-H315 PolarHBondContact O-N 3.5Å; L312-L316 HydrophobicContact CD1-CD1 4.04Å; L312-L316 HydrophobicContact CD1-CD2 4.27Å; L312-L316 HydrophobicContact CD1-CG 3.75Å; L312-L316 HydrophobicContact CD2-CD1 3.96Å; L312-L316 HydrophobicContact CG-CD1 3.59Å; L312-L316 HydrophobicContact CG-CG 3.84Å; L312-L316 WeakPolarHBondContact O-CB 3.18Å; L312-L316 VanDerWaalsContact O-CG 3.27Å; L312-L316 WeakPolarHBondContact O-CG 3.45Å; L312-L316 PolarHBondContact O-N 3.07Å
313S57.5Low59.2Low55 Ų55100.7 Ų100.739%0.38550%0.501SS..Hα-helixtrans-64.3-37.9-175.676.20000112.9I310 A311 K317I310-S313 WeakPolarHBondContact O-CB 3.33Å; I310-S313 PolarHBondContact O-N 3.26Å; I310-S313 PolarHBondContact O-OG 3Å; A311-S313 VanDerWaalsContact C-N 3.26Å; A311-S313 PolarHBondContact O-N 3.21Å; S313-K317 WeakPolarHBondContact O-CB 3.18Å; S313-K317 PolarHBondContact O-N 2.88Å
314E58.2Low59.6Low108 Ų10898.6 Ų98.651%0.50549%0.491SS..Hα-helixtrans-74.2-39.3179.6-77.3-63.8137.200112L312 K317 Q318L312-E314 PolarHBondContact O-N 2.96Å; E314-K317 PolarHBondContact O-N 3.24Å; E314-K317 IonicContact OE1-NZ 2.74Å; E314-K317 PolarHBondContact OE1-NZ 3.03Å; E314-K317 IonicContact OE2-NZ 2.82Å; E314-Q318 WeakPolarHBondContact O-CB 3.48Å; E314-Q318 PolarHBondContact O-N 3.48Å
315H60.8Low60.2Low124 Ų12490.5 Ų90.557%0.57446%0.462SS*.Hα-helixtrans-66.8-40.3172.4-80.3-78.8000112.4L312 Q318 R319L312-H315 PolarHBondContact O-N 3.5Å; H315-Q318 PolarHBondContact O-N 3.35Å; H315-R319 VanDerWaalsContact O-CG 3.3Å; H315-R319 WeakPolarHBondContact O-CG 3.41Å; H315-R319 PolarHBondContact O-N 3.43Å
316L63Low61.1Low32 Ų3284.5 Ų84.517%0.16843%0.431CS..Hα-helixtrans-67.5-35.8173.9-72.6-179.4000112.2M300 L312 R319 R320M300-L316 HydrophobicContact CE-CB 4.06Å; M300-L316 HydrophobicContact CE-CD2 4.31Å; L312-L316 HydrophobicContact CD1-CD1 4.04Å; L312-L316 HydrophobicContact CD1-CD2 4.27Å; L312-L316 HydrophobicContact CD1-CG 3.75Å; L312-L316 HydrophobicContact CD2-CD1 3.96Å; L312-L316 HydrophobicContact CG-CD1 3.59Å; L312-L316 HydrophobicContact CG-CG 3.84Å; L312-L316 WeakPolarHBondContact O-CB 3.18Å; L312-L316 VanDerWaalsContact O-CG 3.27Å; L312-L316 WeakPolarHBondContact O-CG 3.45Å; L312-L316 PolarHBondContact O-N 3.07Å; L316-R319 PolarHBondContact O-N 2.81Å; L316-R320 WeakPolarHBondContact O-CB 3.45Å; L316-R320 PolarHBondContact O-N 3.41Å
317K65.6Low61.9Low111 Ų11186 Ų8648%0.48343%0.425SS..Hα-helixtrans-64.5-43.9174-179.8179.5172.6-168.70111S313 E314 R319 R320 E321S313-K317 WeakPolarHBondContact O-CB 3.18Å; S313-K317 PolarHBondContact O-N 2.88Å; E314-K317 PolarHBondContact O-N 3.24Å; E314-K317 IonicContact OE1-NZ 2.74Å; E314-K317 PolarHBondContact OE1-NZ 3.03Å; E314-K317 IonicContact OE2-NZ 2.82Å; K317-R319 VanDerWaalsContact C-N 3.34Å; K317-R319 PolarHBondContact O-N 3.34Å; K317-R320 WeakPolarHBondContact O-CB 3.41Å; K317-R320 PolarHBondContact O-N 3.13Å; K317-E321 WeakPolarHBondContact O-CG 3.39Å; K317-E321 PolarHBondContact O-N 2.95Å
318Q63.3Low63.4Low135 Ų13580.7 Ų80.763%0.63139%0.393SS*.Hα-helixtrans-63.7-39.4174.5-159.6173.3-6.600111.7E314 H315 E321 V322E314-Q318 WeakPolarHBondContact O-CB 3.48Å; E314-Q318 PolarHBondContact O-N 3.48Å; H315-Q318 PolarHBondContact O-N 3.35Å; Q318-E321 PolarHBondContact O-N 3.02Å; Q318-V322 WeakPolarHBondContact O-CG2 3.48Å; Q318-V322 PolarHBondContact O-N 3.17Å
319R64.9Low64.5Low79 Ų7976 Ų7630%0.29837%0.369SS..Hα-helixtrans-64.5-37.8172.5-71.7176.2-178.7-163-2.8112.6A204 V205 H315 L316 K317 V322 A323A204-R319 VanDerWaalsContact O-CZ 3.24Å; A204-R319 PolarHBondContact O-NH1 3.47Å; V205-R319 HydrophobicContact CG2-CB 4.28Å; H315-R319 VanDerWaalsContact O-CG 3.3Å; H315-R319 WeakPolarHBondContact O-CG 3.41Å; H315-R319 PolarHBondContact O-N 3.43Å; L316-R319 PolarHBondContact O-N 2.81Å; K317-R319 VanDerWaalsContact C-N 3.34Å; K317-R319 PolarHBondContact O-N 3.34Å; R319-V322 PolarHBondContact O-N 3.48Å; R319-A323 PolarHBondContact O-N 2.91Å
320R66.2Low65.8Low141 Ų14166.3 Ų66.353%0.53233%0.333SS..Hα-helixtrans-63.9-43175.3-170.2-179.9-178.3-173.40.4112M300 L316 K317 V322 A323 K324M300-R320 HydrophobicContact CE-CB 4.22Å; L316-R320 WeakPolarHBondContact O-CB 3.45Å; L316-R320 PolarHBondContact O-N 3.41Å; K317-R320 WeakPolarHBondContact O-CB 3.41Å; K317-R320 PolarHBondContact O-N 3.13Å; R320-V322 VanDerWaalsContact C-N 3.33Å; R320-A323 PolarHBondContact O-N 2.89Å; R320-K324 HydrophobicContact CG-CD 4.47Å; R320-K324 WeakPolarHBondContact O-CB 3.37Å; R320-K324 VanDerWaalsContact O-CG 3.29Å; R320-K324 WeakPolarHBondContact O-CG 3.3Å; R320-K324 PolarHBondContact O-N 3.42Å
321E68.1Low67.3Low97 Ų9763.6 Ų63.645%0.45332%0.319SS..Hα-helixtrans-64.8-38.5177.6-68.2-55.112300111.6K317 Q318 K324 A325K317-E321 WeakPolarHBondContact O-CG 3.39Å; K317-E321 PolarHBondContact O-N 2.95Å; Q318-E321 PolarHBondContact O-N 3.02Å; E321-K324 IonicContact OE1-NZ 2.64Å; E321-K324 PolarHBondContact OE1-NZ 3.45Å; E321-A325 PolarHBondContact O-N 3.08Å
322V64.4Low68.9Low52 Ų5261 Ų6132%0.31529%0.293SS..Hα-helixtrans-67-39.7174.61770000111.7R201 Q318 R319 R320 A325 V326R201-V322 HydrophobicContact CG-CG1 4.47Å; Q318-V322 WeakPolarHBondContact O-CG2 3.48Å; Q318-V322 PolarHBondContact O-N 3.17Å; R319-V322 PolarHBondContact O-N 3.48Å; R320-V322 VanDerWaalsContact C-N 3.33Å; V322-A325 WeakPolarHBondContact O-CB 3.21Å; V322-A325 PolarHBondContact O-N 3.22Å; V322-V326 PolarHBondContact O-N 3.34Å; V322-V326 VanDerWaalsContact O-N 3.12Å
323A66.6Low70.5Confident5 Ų559.5 Ų59.54%0.04129%0.286CS..Hα-helixtrans-72.3-37.3177.300000113.8M296 R319 R320 A325 V326 F327M296-A323 HydrophobicContact CE-CB 3.18Å; M296-A323 HydrophobicContact SD-CB 3.26Å; M296-A323 WeakPolarHBondContact SD-CB 3.05Å; R319-A323 PolarHBondContact O-N 2.91Å; R320-A323 PolarHBondContact O-N 2.89Å; A323-A325 PolarHBondContact O-N 3.49Å; A323-V326 PolarHBondContact O-N 2.93Å; A323-F327 PolarHBondContact O-N 2.97Å
324K69.8Low72.1Confident45 Ų4557.8 Ų57.820%0.19627%0.274CS..Hα-helixtrans-57.2-39.7168.6-76.8175-177.8170.90110.9R320 E321 F327 C328R320-K324 HydrophobicContact CG-CD 4.47Å; R320-K324 WeakPolarHBondContact O-CB 3.37Å; R320-K324 VanDerWaalsContact O-CG 3.29Å; R320-K324 WeakPolarHBondContact O-CG 3.3Å; R320-K324 PolarHBondContact O-N 3.42Å; E321-K324 IonicContact OE1-NZ 2.64Å; E321-K324 PolarHBondContact OE1-NZ 3.45Å; K324-F327 PolarHBondContact O-N 2.95Å; K324-C328 WeakPolarHBondContact O-CB 3.44Å; K324-C328 PolarHBondContact O-N 2.7Å; K324-C328 PolarHBondContact O-SG 2.93Å
325A70.6Confident73.6Confident10 Ų1057 Ų578%0.08327%0.274CS..Hα-helixtrans-64.2-41.517600000112.9E321 V322 A323 C328 L329 V390E321-A325 PolarHBondContact O-N 3.08Å; V322-A325 WeakPolarHBondContact O-CB 3.21Å; V322-A325 PolarHBondContact O-N 3.22Å; A323-A325 PolarHBondContact O-N 3.49Å; A325-C328 PolarHBondContact O-N 3.33Å; A325-L329 WeakPolarHBondContact O-CG 3.28Å; A325-L329 PolarHBondContact O-N 2.74Å; A325-V390 HydrophobicContact CB-CB 4.04Å; A325-V390 HydrophobicContact CB-CG1 3.31Å; A325-V390 HydrophobicContact CB-CG2 3.54Å
326V69.6Low75.1Confident15 Ų1551.3 Ų51.39%0.09125%0.248CC..Hα-helixtrans-64.6-42.2174.1176.50000111.5S198 R201 V322 A323 C328 L329 V330S198-V326 WeakPolarHBondContact OG-CG1 3.3Å; R201-V326 HydrophobicContact CG-CG2 3.78Å; V322-V326 PolarHBondContact O-N 3.34Å; V322-V326 VanDerWaalsContact O-N 3.12Å; A323-V326 PolarHBondContact O-N 2.93Å; V326-C328 PolarHBondContact O-N 3.47Å; V326-L329 WeakPolarHBondContact O-CB 3.3Å; V326-L329 PolarHBondContact O-N 3.05Å; V326-V330 WeakPolarHBondContact O-CG2 3.28Å; V326-V330 PolarHBondContact O-N 3.37Å; V326-V330 VanDerWaalsContact O-N 3.08Å
327F75.3Confident76.4Confident74 Ų7450.1 Ų50.133%0.32524%0.241SC..Hα-helixtrans-61.9-42.7173.8-179.7-103.3000112.1Y293 A323 K324 V330 L331Y293-F327 HydrophobicContact CD1-CD2 4.3Å; Y293-F327 HydrophobicContact CD2-CB 4.06Å; Y293-F327 HydrophobicContact CD2-CD2 4.43Å; Y293-F327 HydrophobicContact CD2-CG 4.49Å; Y293-F327 HydrophobicContact CE2-CB 3.99Å; Y293-F327 HydrophobicContact CE2-CG 4.37Å; Y293-F327 HydrophobicContact CG-CD2 4.25Å; A323-F327 PolarHBondContact O-N 2.97Å; K324-F327 PolarHBondContact O-N 2.95Å; F327-V330 PolarHBondContact O-N 3.08Å; F327-L331 HydrophobicContact CD1-CD1 3.84Å; F327-L331 HydrophobicContact CD1-CG 4.31Å; F327-L331 HydrophobicContact CE1-CD1 3.28Å; F327-L331 HydrophobicContact CE1-CG 3.9Å; F327-L331 HydrophobicContact CE2-CG 4.47Å; F327-L331 HydrophobicContact CZ-CD1 3.76Å; F327-L331 HydrophobicContact CZ-CD2 4.17Å; F327-L331 HydrophobicContact CZ-CG 3.97Å; F327-L331 PolarHBondContact O-N 3.43Å
328C78.9Confident77.6Confident29 Ų2949.5 Ų49.520%0.19624%0.238CC..Hα-helixtrans-62.3-41174-74.60000112.4K324 A325 V326 V330 L331 I332K324-C328 WeakPolarHBondContact O-CB 3.44Å; K324-C328 PolarHBondContact O-N 2.7Å; K324-C328 PolarHBondContact O-SG 2.93Å; A325-C328 PolarHBondContact O-N 3.33Å; V326-C328 PolarHBondContact O-N 3.47Å; C328-V330 VanDerWaalsContact C-N 3.27Å; C328-V330 PolarHBondContact O-N 2.82Å; C328-L331 PolarHBondContact O-N 3.17Å; C328-I332 WeakPolarHBondContact O-CB 3.29Å; C328-I332 VanDerWaalsContact O-CG1 3.3Å; C328-I332 WeakPolarHBondContact O-CG1 3.33Å; C328-I332 PolarHBondContact O-N 2.91Å
329L77.9Confident78.9Confident20 Ų2043.6 Ų43.611%0.10521%0.211CC..Hα-helixtrans-56.8-43.6174.6-79.2162.1000111L194 A325 V326 I332 F333 I386L194-L329 HydrophobicContact CD2-CB 4.45Å; A325-L329 WeakPolarHBondContact O-CG 3.28Å; A325-L329 PolarHBondContact O-N 2.74Å; V326-L329 WeakPolarHBondContact O-CB 3.3Å; V326-L329 PolarHBondContact O-N 3.05Å; L329-I332 PolarHBondContact O-N 3.27Å; L329-F333 WeakPolarHBondContact O-CB 3.21Å; L329-F333 PolarHBondContact O-N 3.48Å; L329-I386 HydrophobicContact CD1-CG2 4.45Å; L329-I386 HydrophobicContact CD2-CB 4.1Å; L329-I386 HydrophobicContact CD2-CD1 3.31Å; L329-I386 HydrophobicContact CD2-CG1 4.31Å; L329-I386 HydrophobicContact CD2-CG2 3.98Å; L329-I386 HydrophobicContact CG-CD1 3.96Å; L329-I386 HydrophobicContact CG-CG2 4.02Å
330V81.1Confident80.2Confident6 Ų640 Ų404%0.03620%0.198CC..Hα-helixtrans-75.4-34.5-177.9173.50000112.6L286 T289 V326 F327 C328 I332 F333 A334L286-V330 HydrophobicContact CD2-CG1 3.68Å; T289-V330 HydrophobicContact CG2-CB 3.9Å; T289-V330 HydrophobicContact CG2-CG1 3.97Å; T289-V330 HydrophobicContact CG2-CG2 3.71Å; T289-V330 WeakPolarHBondContact OG1-CG2 3.28Å; V326-V330 WeakPolarHBondContact O-CG2 3.28Å; V326-V330 PolarHBondContact O-N 3.37Å; V326-V330 VanDerWaalsContact O-N 3.08Å; F327-V330 PolarHBondContact O-N 3.08Å; C328-V330 VanDerWaalsContact C-N 3.27Å; C328-V330 PolarHBondContact O-N 2.82Å; V330-I332 VanDerWaalsContact C-N 3.35Å; V330-F333 WeakPolarHBondContact O-CB 3.38Å; V330-F333 PolarHBondContact O-N 3.42Å; V330-A334 PolarHBondContact O-N 3.25Å
331L84.7Confident81.4Confident82 Ų8233.5 Ų33.543%0.42917%0.174SC..Hα-helixtrans-63.7-41.7170.3-76.8-179.5000111.9F327 C328 F333 A334 L335F327-L331 HydrophobicContact CD1-CD1 3.84Å; F327-L331 HydrophobicContact CD1-CG 4.31Å; F327-L331 HydrophobicContact CE1-CD1 3.28Å; F327-L331 HydrophobicContact CE1-CG 3.9Å; F327-L331 HydrophobicContact CE2-CG 4.47Å; F327-L331 HydrophobicContact CZ-CD1 3.76Å; F327-L331 HydrophobicContact CZ-CD2 4.17Å; F327-L331 HydrophobicContact CZ-CG 3.97Å; F327-L331 PolarHBondContact O-N 3.43Å; C328-L331 PolarHBondContact O-N 3.17Å; L331-F333 VanDerWaalsContact C-N 3.35Å; L331-A334 WeakPolarHBondContact O-CB 3.39Å; L331-A334 PolarHBondContact O-N 3.4Å; L331-L335 WeakPolarHBondContact O-CG 3.42Å; L331-L335 PolarHBondContact O-N 3.49Å
332I86.9Confident82.4Confident30 Ų3031.8 Ų31.815%0.15417%0.168CC..Hα-helixtrans-65.2-43.6176.9-72.2166.1000110C328 L329 V330 A334 L335 C336 I382 I386C328-I332 WeakPolarHBondContact O-CB 3.29Å; C328-I332 VanDerWaalsContact O-CG1 3.3Å; C328-I332 WeakPolarHBondContact O-CG1 3.33Å; C328-I332 PolarHBondContact O-N 2.91Å; L329-I332 PolarHBondContact O-N 3.27Å; V330-I332 VanDerWaalsContact C-N 3.35Å; I332-A334 VanDerWaalsContact C-N 3.31Å; I332-A334 PolarHBondContact O-N 3.38Å; I332-L335 PolarHBondContact O-N 2.83Å; I332-C336 VanDerWaalsContact O-CB 3.27Å; I332-C336 WeakPolarHBondContact O-CB 3.48Å; I332-C336 PolarHBondContact O-N 2.78Å; I332-C336 PolarHBondContact O-SG 2.96Å; I332-I382 HydrophobicContact CD1-CG2 4.29Å; I332-I382 HydrophobicContact CG2-CB 4.48Å; I332-I382 HydrophobicContact CG2-CD1 3.74Å; I332-I382 HydrophobicContact CG2-CG2 4.07Å; I332-I386 HydrophobicContact CD1-CD1 3.56Å; I332-I386 HydrophobicContact CD1-CG1 4.4Å
333F87.9Confident83.5Confident0 Ų029.5 Ų29.50%015%0.154CC..Hα-helixtrans-52.4-50170172.8-91000111.2V191 L194 Y281 F282 P285 L329 V330 L331 L335 C336 W337 N379V191-F333 HydrophobicContact CG2-CE2 3.79Å; V191-F333 HydrophobicContact CG2-CZ 3.58Å; L194-F333 HydrophobicContact CD1-CB 4.13Å; L194-F333 HydrophobicContact CD1-CD2 3.84Å; L194-F333 HydrophobicContact CD1-CE2 4.49Å; L194-F333 HydrophobicContact CD1-CG 3.95Å; Y281-F333 VanDerWaalsContact O-CZ 3.29Å; Y281-F333 WeakPolarHBondContact O-CZ 3.38Å; F282-F333 HydrophobicContact CD2-CE1 4.42Å; P285-F333 HydrophobicContact CB-CE1 4.37Å; P285-F333 HydrophobicContact CG-CD1 4.47Å; P285-F333 HydrophobicContact CG-CE1 3.67Å; P285-F333 HydrophobicContact CG-CZ 4.12Å; L329-F333 WeakPolarHBondContact O-CB 3.21Å; L329-F333 PolarHBondContact O-N 3.48Å; V330-F333 WeakPolarHBondContact O-CB 3.38Å; V330-F333 PolarHBondContact O-N 3.42Å; L331-F333 VanDerWaalsContact C-N 3.35Å; F333-L335 PolarHBondContact O-N 2.9Å; F333-C336 PolarHBondContact O-N 3.14Å; F333-W337 AromaticContact CD2-CD1 3.3Å; F333-W337 HydrophobicContact CD2-CG 4.14Å; F333-W337 AromaticContact CD2-NE1 3.49Å; F333-W337 AromaticContact CE2-CD1 3.28Å; F333-W337 HydrophobicContact CE2-CD2 4.06Å; F333-W337 AromaticContact CE2-CE2 3.89Å; F333-W337 AromaticContact CE2-CG 3.74Å; F333-W337 HydrophobicContact CE2-CG 3.74Å; F333-W337 AromaticContact CE2-NE1 3.33Å; F333-W337 VanDerWaalsContact CE2-NE1 3.33Å; F333-W337 AromaticContact CG-CD1 3.93Å; F333-W337 HydrophobicContact CZ-CB 4.4Å; F333-W337 AromaticContact CZ-CD1 3.89Å; F333-W337 HydrophobicContact CZ-CD2 4.33Å; F333-W337 AromaticContact CZ-CG 3.93Å; F333-W337 HydrophobicContact CZ-CG 3.93Å; F333-W337 WeakPolarHBondContact O-CB 3.36Å; F333-W337 PolarHBondContact O-N 2.82Å; F333-N379 VanDerWaalsContact CA-OD1 3.29Å; F333-N379 WeakPolarHBondContact CA-OD1 3.17Å
334A89.6Confident84.6Confident18 Ų1831.9 Ų31.915%0.14916%0.161CC..Hα-helixtrans-57-49.5178.300000112F282 L286 V330 L331 I332 C336 W337 F338F282-A334 HydrophobicContact CE2-CB 4.49Å; L286-A334 HydrophobicContact CD1-CB 4.44Å; L286-A334 HydrophobicContact CD2-CB 3.7Å; V330-A334 PolarHBondContact O-N 3.25Å; L331-A334 WeakPolarHBondContact O-CB 3.39Å; L331-A334 PolarHBondContact O-N 3.4Å; I332-A334 VanDerWaalsContact C-N 3.31Å; I332-A334 PolarHBondContact O-N 3.38Å; A334-C336 VanDerWaalsContact C-N 3.35Å; A334-C336 PolarHBondContact O-N 2.97Å; A334-W337 PolarHBondContact O-N 3.38Å; A334-F338 WeakPolarHBondContact O-CB 3.43Å; A334-F338 PolarHBondContact O-N 2.92Å
335L90.6Very high85.6Confident93 Ų9331 Ų3149%0.48716%0.159SC..Hα-helixtrans-65.9-36.7-177.9-68.7173.4000112.7L331 I332 F333 P339L331-L335 WeakPolarHBondContact O-CG 3.42Å; L331-L335 PolarHBondContact O-N 3.49Å; I332-L335 PolarHBondContact O-N 2.83Å; F333-L335 PolarHBondContact O-N 2.9Å; L335-P339 WeakPolarHBondContact O-CD 3.2Å
336C91.4Very high86.4Confident4 Ų433.3 Ų33.33%0.02717%0.169CC..Hα-helixtrans-73.2-39.4178.7-800000112.6I332 F333 A334 L375 A376 N379I332-C336 VanDerWaalsContact O-CB 3.27Å; I332-C336 WeakPolarHBondContact O-CB 3.48Å; I332-C336 PolarHBondContact O-N 2.78Å; I332-C336 PolarHBondContact O-SG 2.96Å; F333-C336 PolarHBondContact O-N 3.14Å; A334-C336 VanDerWaalsContact C-N 3.35Å; A334-C336 PolarHBondContact O-N 2.97Å; C336-L375 WeakPolarHBondContact CB-O 3.24Å; C336-L375 CarbonylContact O-C 3.5Å; C336-L375 WeakPolarHBondContact O-CB 3.3Å; C336-L375 PolarHBondContact SG-O 3.11Å; C336-A376 PolarHBondContact O-N 3.06Å; C336-N379 HydrophobicContact CB-CB 3.73Å
337W90.9Very high87.1Confident7 Ų738 Ų383%0.02719%0.188CC..Hα-helixtrans-88.9-27.2-174.7-77.283.3000113.5V187 F282 F333 A334 L340 H341 A376 N379V187-W337 HydrophobicContact CB-CH2 4Å; V187-W337 HydrophobicContact CB-CZ2 4.41Å; V187-W337 HydrophobicContact CG1-CE3 4.37Å; V187-W337 HydrophobicContact CG1-CH2 3.46Å; V187-W337 VanDerWaalsContact CG1-CH2 3.46Å; V187-W337 HydrophobicContact CG1-CZ2 3.79Å; V187-W337 HydrophobicContact CG1-CZ3 3.73Å; V187-W337 HydrophobicContact CG2-CH2 3.16Å; V187-W337 HydrophobicContact CG2-CZ2 3.72Å; V187-W337 HydrophobicContact CG2-CZ3 4.01Å; F282-W337 HydrophobicContact CD2-CB 3.98Å; F282-W337 HydrophobicContact CE2-CB 4.23Å; F333-W337 AromaticContact CD2-CD1 3.3Å; F333-W337 HydrophobicContact CD2-CG 4.14Å; F333-W337 AromaticContact CD2-NE1 3.49Å; F333-W337 AromaticContact CE2-CD1 3.28Å; F333-W337 HydrophobicContact CE2-CD2 4.06Å; F333-W337 AromaticContact CE2-CE2 3.89Å; F333-W337 AromaticContact CE2-CG 3.74Å; F333-W337 HydrophobicContact CE2-CG 3.74Å; F333-W337 AromaticContact CE2-NE1 3.33Å; F333-W337 VanDerWaalsContact CE2-NE1 3.33Å; F333-W337 AromaticContact CG-CD1 3.93Å; F333-W337 HydrophobicContact CZ-CB 4.4Å; F333-W337 AromaticContact CZ-CD1 3.89Å; F333-W337 HydrophobicContact CZ-CD2 4.33Å; F333-W337 AromaticContact CZ-CG 3.93Å; F333-W337 HydrophobicContact CZ-CG 3.93Å; F333-W337 WeakPolarHBondContact O-CB 3.36Å; F333-W337 PolarHBondContact O-N 2.82Å; A334-W337 PolarHBondContact O-N 3.38Å; W337-L340 HydrophobicContact CE3-CD2 4.32Å; W337-L340 HydrophobicContact CZ3-CD2 4.03Å; W337-L340 PolarHBondContact O-N 3.46Å; W337-H341 AromaticContact CE3-NE2 3.8Å; W337-H341 PolarHBondContact O-CD2 3.22Å; W337-H341 VanDerWaalsContact O-CD2 3.28Å; W337-H341 PolarHBondContact O-N 3.43Å; W337-A376 HydrophobicContact CD2-CB 4.15Å; W337-A376 HydrophobicContact CE3-CB 4.29Å; W337-A376 HydrophobicContact CH2-CB 3.94Å; W337-A376 HydrophobicContact CZ2-CB 3.91Å; W337-A376 HydrophobicContact CZ3-CB 4.2Å; W337-N379 PolarHBondContact NE1-ND2 3.42Å
338F91.5Very high87.6Confident97 Ų9737.7 Ų37.743%0.42519%0.187SC..Hα-helixtrans-55.9-46.2-176.3175.9-103.4000113.9F282 A334 L340 H341 L342F282-F338 HydrophobicContact CE1-CD2 4.45Å; F282-F338 HydrophobicContact CE2-CB 3.98Å; F282-F338 HydrophobicContact CZ-CB 3.97Å; F282-F338 AromaticContact CZ-CD2 3.94Å; F282-F338 HydrophobicContact CZ-CD2 3.94Å; F282-F338 HydrophobicContact CZ-CG 4.46Å; A334-F338 WeakPolarHBondContact O-CB 3.43Å; A334-F338 PolarHBondContact O-N 2.92Å; F338-L340 VanDerWaalsContact C-N 3.27Å; F338-L340 PolarHBondContact O-N 3.24Å; F338-H341 PolarHBondContact O-N 3.23Å; F338-L342 HydrophobicContact CE1-CB 4.48Å; F338-L342 HydrophobicContact CE1-CD2 3.83Å; F338-L342 HydrophobicContact CZ-CB 4.41Å; F338-L342 HydrophobicContact CZ-CD1 4.46Å; F338-L342 HydrophobicContact CZ-CD2 4.01Å; F338-L342 VanDerWaalsContact O-CB 3.28Å; F338-L342 WeakPolarHBondContact O-CB 3.35Å; F338-L342 PolarHBondContact O-N 3.34Å
339P90.8Very high87.8Confident11 Ų1142.1 Ų42.17%0.07121%0.207CC..Hα-helixtrans-60.1-36.2-178.8-26.537.8000113.3M16 L335 S343 L375M16-P339 HydrophobicContact CE-CB 4.01Å; M16-P339 HydrophobicContact CE-CG 4.12Å; L335-P339 WeakPolarHBondContact O-CD 3.2Å; P339-S343 WeakPolarHBondContact O-CB 3.44Å; P339-S343 PolarHBondContact O-N 3.33Å; P339-S343 PolarHBondContact O-OG 2.89Å; P339-L375 HydrophobicContact CG-CD2 3.8Å
340L90.8Very high88Confident3 Ų344.7 Ų44.72%0.01622%0.223CC..Hα-helixtrans-70.2-42.3177.8-177.761.9000112.2W337 F338 S343 R344 D369 I373 A376W337-L340 HydrophobicContact CE3-CD2 4.32Å; W337-L340 HydrophobicContact CZ3-CD2 4.03Å; W337-L340 PolarHBondContact O-N 3.46Å; F338-L340 VanDerWaalsContact C-N 3.27Å; F338-L340 PolarHBondContact O-N 3.24Å; L340-S343 PolarHBondContact O-OG 2.9Å; L340-R344 WeakPolarHBondContact O-CG 3.28Å; L340-R344 PolarHBondContact O-N 2.85Å; L340-D369 WeakPolarHBondContact CD1-OD1 3.31Å; L340-I373 HydrophobicContact CD1-CG1 3.9Å; L340-A376 HydrophobicContact CD2-CB 4.16Å
341H91.4Very high87.8Confident6 Ų648 Ų483%0.02824%0.235CC..Hα-helixtrans-68-40.1175.8-75.9-73.8000111.2L277 F278 F282 W337 F338 R344 I345L277-H341 PolarHBondContact O-CE1 2.95Å; F278-H341 HydrophobicContact CD2-CB 3.91Å; F282-H341 AromaticContact CD2-CD2 3.81Å; W337-H341 AromaticContact CE3-NE2 3.8Å; W337-H341 PolarHBondContact O-CD2 3.22Å; W337-H341 VanDerWaalsContact O-CD2 3.28Å; W337-H341 PolarHBondContact O-N 3.43Å; F338-H341 PolarHBondContact O-N 3.23Å; H341-R344 PolarHBondContact O-N 2.82Å; H341-I345 VanDerWaalsContact O-CG1 3.3Å; H341-I345 WeakPolarHBondContact O-CG1 3.39Å; H341-I345 PolarHBondContact O-N 2.78Å
342L89.4Confident87.4Confident61 Ų6152.8 Ų52.832%0.31925%0.247SC..Hα-helixtrans-61.5-47177.4-178.363.1000111.5F338 R344 I345 L346F338-L342 HydrophobicContact CE1-CB 4.48Å; F338-L342 HydrophobicContact CE1-CD2 3.83Å; F338-L342 HydrophobicContact CZ-CB 4.41Å; F338-L342 HydrophobicContact CZ-CD1 4.46Å; F338-L342 HydrophobicContact CZ-CD2 4.01Å; F338-L342 VanDerWaalsContact O-CB 3.28Å; F338-L342 WeakPolarHBondContact O-CB 3.35Å; F338-L342 PolarHBondContact O-N 3.34Å; L342-R344 VanDerWaalsContact C-N 3.3Å; L342-R344 PolarHBondContact O-N 3.25Å; L342-I345 PolarHBondContact O-N 3.33Å; L342-L346 HydrophobicContact CD1-CD1 3.99Å; L342-L346 HydrophobicContact CD1-CG 3.97Å; L342-L346 HydrophobicContact CD2-CD1 4.45Å; L342-L346 HydrophobicContact CG-CD1 3.81Å; L342-L346 HydrophobicContact CG-CG 4.22Å; L342-L346 VanDerWaalsContact O-CB 3.32Å; L342-L346 WeakPolarHBondContact O-CB 3.17Å; L342-L346 VanDerWaalsContact O-CG 3.25Å; L342-L346 WeakPolarHBondContact O-CG 3.41Å; L342-L346 PolarHBondContact O-N 2.88Å
343S88.7Confident86.5Confident3 Ų354.9 Ų54.92%0.02126%0.263CS..Hα-helixtrans-59.4-41179.468.90000112.1P339 L340 K347P339-S343 WeakPolarHBondContact O-CB 3.44Å; P339-S343 PolarHBondContact O-N 3.33Å; P339-S343 PolarHBondContact O-OG 2.89Å; L340-S343 PolarHBondContact O-OG 2.9Å; S343-K347 WeakPolarHBondContact O-CB 3.48Å; S343-K347 PolarHBondContact O-N 3.34Å
344R89.6Confident85.6Confident55 Ų5563.4 Ų63.421%0.20830%0.3CS..Hα-helixtrans-68.1-45.5178.4-69.9179.3-178.9160.92.5112.6K184 L340 H341 L342 K347 K348K184-R344 VanDerWaalsContact NZ-NH1 3.2Å; L340-R344 WeakPolarHBondContact O-CG 3.28Å; L340-R344 PolarHBondContact O-N 2.85Å; H341-R344 PolarHBondContact O-N 2.82Å; L342-R344 VanDerWaalsContact C-N 3.3Å; L342-R344 PolarHBondContact O-N 3.25Å; R344-K347 WeakPolarHBondContact O-CB 3.46Å; R344-K347 PolarHBondContact O-N 3.32Å; R344-K348 PolarHBondContact O-N 3Å
345I89.8Confident84.9Confident27 Ų2766.1 Ų66.114%0.13831%0.312CS..Hα-helixtrans-66.2-42177.7-64.1-64.5000110.8D274 W275 H341 L342 K347 K348 M349D274-I345 HydrophobicContact CB-CD1 4.01Å; W275-I345 HydrophobicContact CD2-CD1 4.18Å; W275-I345 HydrophobicContact CE3-CD1 4.07Å; W275-I345 HydrophobicContact CH2-CG2 4.44Å; W275-I345 HydrophobicContact CZ3-CD1 4.27Å; H341-I345 VanDerWaalsContact O-CG1 3.3Å; H341-I345 WeakPolarHBondContact O-CG1 3.39Å; H341-I345 PolarHBondContact O-N 2.78Å; L342-I345 PolarHBondContact O-N 3.33Å; I345-K347 PolarHBondContact O-N 3.43Å; I345-K348 PolarHBondContact O-N 3.17Å; I345-K348 VanDerWaalsContact O-N 3.13Å; I345-M349 HydrophobicContact CG2-CG 4.07Å; I345-M349 WeakPolarHBondContact O-CB 3.33Å; I345-M349 VanDerWaalsContact O-CG 3.3Å; I345-M349 WeakPolarHBondContact O-CG 3.49Å; I345-M349 PolarHBondContact O-N 3.48Å
346L86.8Confident83.8Confident58 Ų5868.1 Ų68.130%0.30432%0.323SS..Hα-helixtrans-61.1-44.4174.7-74175.6000111.5L342 K348 M349 V350 L365L342-L346 HydrophobicContact CD1-CD1 3.99Å; L342-L346 HydrophobicContact CD1-CG 3.97Å; L342-L346 HydrophobicContact CD2-CD1 4.45Å; L342-L346 HydrophobicContact CG-CD1 3.81Å; L342-L346 HydrophobicContact CG-CG 4.22Å; L342-L346 VanDerWaalsContact O-CB 3.32Å; L342-L346 WeakPolarHBondContact O-CB 3.17Å; L342-L346 VanDerWaalsContact O-CG 3.25Å; L342-L346 WeakPolarHBondContact O-CG 3.41Å; L342-L346 PolarHBondContact O-N 2.88Å; L346-K348 VanDerWaalsContact C-N 3.25Å; L346-K348 PolarHBondContact O-N 3.48Å; L346-M349 PolarHBondContact O-N 2.68Å; L346-V350 HydrophobicContact CD2-CG2 4.23Å; L346-V350 WeakPolarHBondContact O-CB 3.28Å; L346-V350 WeakPolarHBondContact O-CG2 3.17Å; L346-V350 PolarHBondContact O-N 2.91Å; L346-L365 HydrophobicContact CB-CD2 3.94Å
347K85.3Confident82.7Confident113 Ų11372.4 Ų72.449%0.49134%0.344SS..Hα-helixtrans-56.2-42.9173.7-174.6-179.2176.3-176.50110.9S343 R344 I345 Y351 L365S343-K347 WeakPolarHBondContact O-CB 3.48Å; S343-K347 PolarHBondContact O-N 3.34Å; R344-K347 WeakPolarHBondContact O-CB 3.46Å; R344-K347 PolarHBondContact O-N 3.32Å; I345-K347 PolarHBondContact O-N 3.43Å; K347-Y351 WeakPolarHBondContact O-CB 3.1Å; K347-Y351 PolarHBondContact O-N 3.23Å; K347-L365 HydrophobicContact CB-CD1 3.88Å; K347-L365 HydrophobicContact CG-CD1 4.16Å
348K85.1Confident81.9Confident68 Ų6873.9 Ų73.930%0.29635%0.35SS..Hα-helixtrans-70.5-41-179.8-171.5173.7-178.6-172.40113.5E271 R344 I345 L346E271-K348 PolarHBondContact O-NZ 3.08Å; E271-K348 IonicContact OE2-NZ 3.6Å; R344-K348 PolarHBondContact O-N 3Å; I345-K348 PolarHBondContact O-N 3.17Å; I345-K348 VanDerWaalsContact O-N 3.13Å; L346-K348 VanDerWaalsContact C-N 3.25Å; L346-K348 PolarHBondContact O-N 3.48Å
349M84.8Confident81Confident123 Ų12370.5 Ų70.561%0.60634%0.338SS*.Hα-helixtrans-83.3-35.9-172.6-66.9-60.5-65.700113.5W275 I345 L346W275-M349 HydrophobicContact CZ2-SD 4Å; I345-M349 HydrophobicContact CG2-CG 4.07Å; I345-M349 WeakPolarHBondContact O-CB 3.33Å; I345-M349 VanDerWaalsContact O-CG 3.3Å; I345-M349 WeakPolarHBondContact O-CG 3.49Å; I345-M349 PolarHBondContact O-N 3.48Å; L346-M349 PolarHBondContact O-N 2.68Å
350V80.8Confident80.3Confident74 Ų7474.8 Ų74.845%0.44836%0.357SS..Hα-helixtrans-102.4-28-169.2-172.70000111.9L346 R352 L361L346-V350 HydrophobicContact CD2-CG2 4.23Å; L346-V350 WeakPolarHBondContact O-CB 3.28Å; L346-V350 WeakPolarHBondContact O-CG2 3.17Å; L346-V350 PolarHBondContact O-N 2.91Å; V350-R352 PolarHBondContact O-N 3Å; V350-L361 HydrophobicContact CB-CD2 4.27Å; V350-L361 HydrophobicContact CG1-CD2 3.75Å
351Y78.1Confident79.8Confident76 Ų7677 Ų7730%0.29837%0.368SS..  trans-67.1109.3-176.9-176.8-100.6000111.7K347 P353 R358K347-Y351 WeakPolarHBondContact O-CB 3.1Å; K347-Y351 PolarHBondContact O-N 3.23Å; Y351-P353 HydrophobicContact CE1-CG 4.21Å; Y351-R358 HydrophobicContact CE2-CB 4.26Å
352R75.1Confident79.2Confident181 Ų18178.8 Ų78.868%0.68338%0.378SS*.  trans-106.1120.2171.6-70.3-174179.5171.91.8110V350 K354 D355V350-R352 PolarHBondContact O-N 3Å; R352-K354 PolarHBondContact O-N 3.19Å; R352-D355 HydrophobicContact CB-CB 4.23Å; R352-D355 PolarHBondContact O-N 3.33Å
353P69.3Low78.7Confident74 Ų7477.6 Ų77.648%0.48138%0.375SS..THydrogen-bonded Turntrans-59.6-24.1-176.4-25.432.7000115P84 Y351 R358P84-P353 WeakPolarHBondContact CB-O 3.34Å; Y351-P353 HydrophobicContact CE1-CG 4.21Å; P353-R358 WeakPolarHBondContact O-CD 3.33Å
354K67.7Low78.5Confident180 Ų18081.1 Ų81.178%0.78339%0.39SS*.THydrogen-bonded Turntrans-95.80.5-174.4-62.6-176.7179.6177.40114.1R352R352-K354 PolarHBondContact O-N 3.19Å
355D74.3Confident78.2Confident74 Ų7478.8 Ų78.840%0.39638%0.381SS..  trans-80.3141.1-178.9-162.9-23.6000111.1R352 M357 R358R352-D355 HydrophobicContact CB-CB 4.23Å; R352-D355 PolarHBondContact O-N 3.33Å; D355-M357 VanDerWaalsContact C-N 3.32Å; D355-M357 PolarHBondContact OD1-N 2.87Å; D355-R358 HydrophobicContact CB-CB 4.44Å; D355-R358 VanDerWaalsContact O-CB 3.31Å; D355-R358 WeakPolarHBondContact O-CB 3.19Å; D355-R358 WeakPolarHBondContact O-CD 3.49Å; D355-R358 WeakPolarHBondContact O-CG 2.91Å; D355-R358 PolarHBondContact O-N 3.42Å
356N67.8Low77.9Confident135 Ų13580 Ų8072%0.72239%0.388SS*.THydrogen-bonded Turntrans-70-30.8176.2-72.2-13.3000111.4R358N356-R358 VanDerWaalsContact C-N 3.26Å; N356-R358 PolarHBondContact O-N 2.96Å
357M69.2Low77.8Confident95 Ų9579.3 Ų79.347%0.46839%0.386SS..THydrogen-bonded Turntrans-83.64.8179.5-62.7-61.7-73.800113.7D355 C359 E360 L361D355-M357 VanDerWaalsContact C-N 3.32Å; D355-M357 PolarHBondContact OD1-N 2.87Å; M357-C359 PolarHBondContact O-N 2.87Å; M357-C359 VanDerWaalsContact O-N 3.12Å; M357-E360 WeakPolarHBondContact CE-OE2 3.32Å; M357-E360 PolarHBondContact O-N 3.36Å; M357-L361 PolarHBondContact O-N 3.41Å
358R72.9Confident77.8Confident38 Ų3874.7 Ų74.714%0.14337%0.366CS..Hα-helixtrans-56.8-32.6-174.570-172.7-171.5117.53.6114.1P85 Y351 P353 D355 N356 L362P85-R358 PolarHBondContact O-NE 2.95Å; P85-R358 PolarHBondContact O-NH2 2.79Å; Y351-R358 HydrophobicContact CE2-CB 4.26Å; P353-R358 WeakPolarHBondContact O-CD 3.33Å; D355-R358 HydrophobicContact CB-CB 4.44Å; D355-R358 VanDerWaalsContact O-CB 3.31Å; D355-R358 WeakPolarHBondContact O-CB 3.19Å; D355-R358 WeakPolarHBondContact O-CD 3.49Å; D355-R358 WeakPolarHBondContact O-CG 2.91Å; D355-R358 PolarHBondContact O-N 3.42Å; N356-R358 VanDerWaalsContact C-N 3.26Å; N356-R358 PolarHBondContact O-N 2.96Å; R358-L362 VanDerWaalsContact O-CB 3.24Å; R358-L362 WeakPolarHBondContact O-CB 3.33Å; R358-L362 PolarHBondContact O-N 3.25Å
359C73.3Confident78Confident25 Ų2573.5 Ų73.517%0.16936%0.363CS..Hα-helixtrans-79.2-32.6-174.8-44.80000111.6C87 M357 S363C87-C359 VanDerWaalsContact CA-SG 3.59Å; C87-C359 HydrophobicContact CB-CB 3.94Å; C87-C359 WeakPolarHBondContact CB-SG 3.25Å; C87-C359 WeakPolarHBondContact SG-CB 3.36Å; C87-C359 CovalentContact SG-SG 2.04Å; C87-C359 PolarHBondContact SG-SG 2.69Å; M357-C359 PolarHBondContact O-N 2.87Å; M357-C359 VanDerWaalsContact O-N 3.12Å; C359-S363 PolarHBondContact O-N 3.38Å; C359-S363 PolarHBondContact O-OG 2.9Å
360E76.9Confident78Confident102 Ų10268.6 Ų68.648%0.47734%0.339SS..Hα-helixtrans-72-47.3174.7-171.4179.7158.700110.9M357 L362 S363 F364M357-E360 WeakPolarHBondContact CE-OE2 3.32Å; M357-E360 PolarHBondContact O-N 3.36Å; E360-L362 VanDerWaalsContact C-N 3.28Å; E360-L362 PolarHBondContact O-N 3.21Å; E360-S363 WeakPolarHBondContact O-CB 3.32Å; E360-S363 PolarHBondContact O-N 3.45Å; E360-F364 PolarHBondContact O-N 3.48Å
361L80Confident78.4Confident49 Ų4967.1 Ų67.126%0.25733%0.328SS..Hα-helixtrans-56.3-44173.1178.663.7000111.1V350 M357 S363 F364 L365V350-L361 HydrophobicContact CB-CD2 4.27Å; V350-L361 HydrophobicContact CG1-CD2 3.75Å; M357-L361 PolarHBondContact O-N 3.41Å; L361-S363 VanDerWaalsContact C-N 3.33Å; L361-S363 PolarHBondContact O-N 3.41Å; L361-F364 PolarHBondContact O-N 2.96Å; L361-L365 HydrophobicContact CD1-CD1 4.12Å; L361-L365 HydrophobicContact CD1-CG 4.21Å; L361-L365 HydrophobicContact CG-CD1 3.87Å; L361-L365 HydrophobicContact CG-CG 4.38Å; L361-L365 WeakPolarHBondContact O-CB 3.45Å; L361-L365 WeakPolarHBondContact O-CG 3.41Å; L361-L365 PolarHBondContact O-N 3.15Å
362L78.6Confident79Confident44 Ų4463.5 Ų63.523%0.2331%0.314CS..Hα-helixtrans-63.3-38.7177.1-173.864000112.1R358 E360 L365 L366R358-L362 VanDerWaalsContact O-CB 3.24Å; R358-L362 WeakPolarHBondContact O-CB 3.33Å; R358-L362 PolarHBondContact O-N 3.25Å; E360-L362 VanDerWaalsContact C-N 3.28Å; E360-L362 PolarHBondContact O-N 3.21Å; L362-L365 PolarHBondContact O-N 3.41Å; L362-L366 HydrophobicContact CG-CD1 4.31Å; L362-L366 WeakPolarHBondContact O-CB 3.31Å; L362-L366 WeakPolarHBondContact O-CG 3.07Å; L362-L366 PolarHBondContact O-N 2.85Å
363S79.4Confident79.7Confident36 Ų3655.7 Ų55.725%0.25229%0.286SS..Hα-helixtrans-65-44177-60.20000111.7P91 C359 E360 L361 L366 V367P91-S363 WeakPolarHBondContact CB-OG 3.44Å; C359-S363 PolarHBondContact O-N 3.38Å; C359-S363 PolarHBondContact O-OG 2.9Å; E360-S363 WeakPolarHBondContact O-CB 3.32Å; E360-S363 PolarHBondContact O-N 3.45Å; L361-S363 VanDerWaalsContact C-N 3.33Å; L361-S363 PolarHBondContact O-N 3.41Å; S363-L366 PolarHBondContact O-N 2.88Å; S363-V367 WeakPolarHBondContact O-CG2 3.17Å; S363-V367 PolarHBondContact O-N 3.25Å; S363-V367 VanDerWaalsContact O-N 3.15Å
364F83.5Confident80.7Confident76 Ų7652.5 Ų52.533%0.33326%0.264SS..Hα-helixtrans-61.7-46.2173.6174.2-104.3000112.1E360 L361 L366 V367 L368E360-F364 PolarHBondContact O-N 3.48Å; L361-F364 PolarHBondContact O-N 2.96Å; F364-L366 VanDerWaalsContact C-N 3.31Å; F364-L366 PolarHBondContact O-N 3.41Å; F364-V367 PolarHBondContact O-N 2.8Å; F364-L368 HydrophobicContact CD1-CD1 3.97Å; F364-L368 HydrophobicContact CD1-CG 4.45Å; F364-L368 HydrophobicContact CE1-CD1 3.26Å; F364-L368 HydrophobicContact CE1-CG 4.01Å; F364-L368 HydrophobicContact CE2-CD1 4.29Å; F364-L368 HydrophobicContact CE2-CG 4.26Å; F364-L368 HydrophobicContact CZ-CD1 3.46Å; F364-L368 VanDerWaalsContact CZ-CD1 3.46Å; F364-L368 HydrophobicContact CZ-CD2 4.31Å; F364-L368 HydrophobicContact CZ-CG 3.9Å; F364-L368 PolarHBondContact O-N 3.45Å
365L84.7Confident81.9Confident7 Ų745.1 Ų45.14%0.03723%0.233CC..Hα-helixtrans-63.8-35.4177.9-70.9171.5000112.3L346 K347 L361 L362 L368 D369L346-L365 HydrophobicContact CB-CD2 3.94Å; K347-L365 HydrophobicContact CB-CD1 3.88Å; K347-L365 HydrophobicContact CG-CD1 4.16Å; L361-L365 HydrophobicContact CD1-CD1 4.12Å; L361-L365 HydrophobicContact CD1-CG 4.21Å; L361-L365 HydrophobicContact CG-CD1 3.87Å; L361-L365 HydrophobicContact CG-CG 4.38Å; L361-L365 WeakPolarHBondContact O-CB 3.45Å; L361-L365 WeakPolarHBondContact O-CG 3.41Å; L361-L365 PolarHBondContact O-N 3.15Å; L362-L365 PolarHBondContact O-N 3.41Å; L365-L368 PolarHBondContact O-N 2.77Å; L365-D369 VanDerWaalsContact O-CB 3.31Å; L365-D369 WeakPolarHBondContact O-CB 3.36Å; L365-D369 PolarHBondContact O-N 3.2Å
366L81.9Confident82.7Confident53 Ų5341.6 Ų41.628%0.27722%0.215SC..Hα-helixtrans-63.4-42.5174.2-78.5168.1000111.6P91 L362 S363 F364 D369 H370P91-L366 HydrophobicContact CB-CD1 4.15Å; L362-L366 HydrophobicContact CG-CD1 4.31Å; L362-L366 WeakPolarHBondContact O-CB 3.31Å; L362-L366 WeakPolarHBondContact O-CG 3.07Å; L362-L366 PolarHBondContact O-N 2.85Å; S363-L366 PolarHBondContact O-N 2.88Å; F364-L366 VanDerWaalsContact C-N 3.31Å; F364-L366 PolarHBondContact O-N 3.41Å; L366-D369 PolarHBondContact O-N 3.03Å; L366-H370 PolarHBondContact O-N 2.78Å; L366-H370 VanDerWaalsContact O-N 3.08Å; L366-H370 PolarHBondContact O-ND1 2.76Å
367V84.8Confident83.8Confident42 Ų4235.1 Ų35.126%0.25518%0.18SC..Hα-helixtrans-63-47.1175.2168.90000110.6F97 S363 F364 D369 H370 L371F97-V367 HydrophobicContact CD2-CG1 4.12Å; F97-V367 HydrophobicContact CE2-CG1 3.64Å; F97-V367 HydrophobicContact CZ-CG1 4.04Å; S363-V367 WeakPolarHBondContact O-CG2 3.17Å; S363-V367 PolarHBondContact O-N 3.25Å; S363-V367 VanDerWaalsContact O-N 3.15Å; F364-V367 PolarHBondContact O-N 2.8Å; V367-D369 VanDerWaalsContact C-N 3.32Å; V367-D369 PolarHBondContact O-N 3.46Å; V367-H370 PolarHBondContact O-N 3.49Å; V367-L371 HydrophobicContact CG1-CD1 4Å; V367-L371 WeakPolarHBondContact O-CB 3.21Å; V367-L371 WeakPolarHBondContact O-CG 3.27Å; V367-L371 PolarHBondContact O-N 2.86Å
368L86.5Confident84.8Confident16 Ų1632.8 Ų32.88%0.08417%0.169CC..Hα-helixtrans-62.5-36.6176.2-74.9-174.2000113M16 F364 L365 G372M16-L368 HydrophobicContact CE-CD2 4.44Å; F364-L368 HydrophobicContact CD1-CD1 3.97Å; F364-L368 HydrophobicContact CD1-CG 4.45Å; F364-L368 HydrophobicContact CE1-CD1 3.26Å; F364-L368 HydrophobicContact CE1-CG 4.01Å; F364-L368 HydrophobicContact CE2-CD1 4.29Å; F364-L368 HydrophobicContact CE2-CG 4.26Å; F364-L368 HydrophobicContact CZ-CD1 3.46Å; F364-L368 VanDerWaalsContact CZ-CD1 3.46Å; F364-L368 HydrophobicContact CZ-CD2 4.31Å; F364-L368 HydrophobicContact CZ-CG 3.9Å; F364-L368 PolarHBondContact O-N 3.45Å; L365-L368 PolarHBondContact O-N 2.77Å; L368-G372 PolarHBondContact O-N 3.05Å
369D87.6Confident85.6Confident43 Ų4331 Ų3123%0.2316%0.163CC..Hα-helixtrans-65.5-45.8177.4-167.159000111L340 L365 L366 V367 G372 I373L340-D369 WeakPolarHBondContact CD1-OD1 3.31Å; L365-D369 VanDerWaalsContact O-CB 3.31Å; L365-D369 WeakPolarHBondContact O-CB 3.36Å; L365-D369 PolarHBondContact O-N 3.2Å; L366-D369 PolarHBondContact O-N 3.03Å; V367-D369 VanDerWaalsContact C-N 3.32Å; V367-D369 PolarHBondContact O-N 3.46Å; D369-G372 PolarHBondContact O-N 2.87Å; D369-I373 WeakPolarHBondContact O-CB 3.4Å; D369-I373 VanDerWaalsContact O-CG1 3.22Å; D369-I373 WeakPolarHBondContact O-CG1 3.35Å; D369-I373 PolarHBondContact O-N 3.38Å
370H86.3Confident86.4Confident21 Ų2130 Ų3010%0.09716%0.155CC..Hα-helixtrans-66.5-40.1177-72.872.8000112.3F97 L366 V367 I373 N374F97-H370 HydrophobicContact CE1-CB 3.79Å; F97-H370 HydrophobicContact CZ-CB 3.83Å; L366-H370 PolarHBondContact O-N 2.78Å; L366-H370 VanDerWaalsContact O-N 3.08Å; L366-H370 PolarHBondContact O-ND1 2.76Å; V367-H370 PolarHBondContact O-N 3.49Å; H370-I373 PolarHBondContact O-N 3.22Å; H370-N374 PolarHBondContact O-N 2.83Å
371L88.3Confident87.1Confident42 Ų4225.4 Ų25.422%0.2213%0.134CC..Hα-helixtrans-62.5-44.1172-73.2174.4000111.4F97 V367 N374 L375F97-L371 HydrophobicContact CE2-CD1 4.2Å; F97-L371 HydrophobicContact CE2-CD2 3.79Å; F97-L371 HydrophobicContact CE2-CG 3.75Å; F97-L371 HydrophobicContact CZ-CD2 4.17Å; F97-L371 HydrophobicContact CZ-CG 3.93Å; V367-L371 HydrophobicContact CG1-CD1 4Å; V367-L371 WeakPolarHBondContact O-CB 3.21Å; V367-L371 WeakPolarHBondContact O-CG 3.27Å; V367-L371 PolarHBondContact O-N 2.86Å; L371-N374 PolarHBondContact O-N 2.86Å; L371-L375 WeakPolarHBondContact O-CD1 3.21Å; L371-L375 PolarHBondContact O-N 2.96Å
372G91.1Very high87.4Confident0 Ų024.9 Ų24.90%013%0.131CC..Hα-helixtrans-63.6-40.9178.300000112.6L368 D369 L375 A376L368-G372 PolarHBondContact O-N 3.05Å; D369-G372 PolarHBondContact O-N 2.87Å; G372-L375 PolarHBondContact O-N 2.89Å; G372-A376 WeakPolarHBondContact O-CB 3.2Å; G372-A376 PolarHBondContact O-N 3.03Å
373I90.6Very high87.7Confident17 Ų1723.1 Ų23.19%0.08712%0.122CC..Hα-helixtrans-61-46.4173.7-71.2164.4000110.1N155 L340 D369 H370 L375 A376 T377N155-I373 WeakPolarHBondContact ND2-CG2 3.49Å; L340-I373 HydrophobicContact CD1-CG1 3.9Å; D369-I373 WeakPolarHBondContact O-CB 3.4Å; D369-I373 VanDerWaalsContact O-CG1 3.22Å; D369-I373 WeakPolarHBondContact O-CG1 3.35Å; D369-I373 PolarHBondContact O-N 3.38Å; H370-I373 PolarHBondContact O-N 3.22Å; I373-L375 PolarHBondContact O-N 3.26Å; I373-A376 PolarHBondContact O-N 3.15Å; I373-T377 WeakPolarHBondContact O-CG2 3.49Å; I373-T377 PolarHBondContact O-N 3.03Å; I373-T377 PolarHBondContact O-OG1 3.36Å
374N90.1Very high88.1Confident7 Ų721.6 Ų21.64%0.03711%0.112CC..Hα-helixtrans-63.1-40.3176.4-84.7-11.9000113.3N101 S105 H370 L371 A376 T377 I378N101-N374 PolarHBondContact ND2-ND2 2.88Å; N101-N374 VanDerWaalsContact ND2-ND2 3.19Å; N101-N374 PolarHBondContact OD1-ND2 2.9Å; S105-N374 PolarHBondContact OG-OD1 3.29Å; H370-N374 PolarHBondContact O-N 2.83Å; L371-N374 PolarHBondContact O-N 2.86Å; N374-A376 VanDerWaalsContact C-N 3.33Å; N374-T377 WeakPolarHBondContact CA-OG1 3.37Å; N374-T377 PolarHBondContact O-N 3.36Å; N374-T377 PolarHBondContact O-OG1 3.33Å; N374-I378 WeakPolarHBondContact O-CB 3.16Å; N374-I378 WeakPolarHBondContact O-CD1 3.46Å; N374-I378 WeakPolarHBondContact O-CG1 3.16Å; N374-I378 PolarHBondContact O-N 3.04Å
375L91.4Very high88.3Confident25 Ų2521.4 Ų21.413%0.13111%0.113CC..Hα-helixtrans-66.6-38.2175.7-96.965.3000111.3M12 C336 P339 L371 G372 I373 I378 N379M12-L375 HydrophobicContact CE-CD2 4.16Å; M12-L375 HydrophobicContact CE-CG 4.44Å; M12-L375 HydrophobicContact SD-CD1 4.48Å; M12-L375 HydrophobicContact SD-CD2 4.11Å; M12-L375 HydrophobicContact SD-CG 4.47Å; C336-L375 WeakPolarHBondContact CB-O 3.24Å; C336-L375 CarbonylContact O-C 3.5Å; C336-L375 WeakPolarHBondContact O-CB 3.3Å; C336-L375 PolarHBondContact SG-O 3.11Å; P339-L375 HydrophobicContact CG-CD2 3.8Å; L371-L375 WeakPolarHBondContact O-CD1 3.21Å; L371-L375 PolarHBondContact O-N 2.96Å; G372-L375 PolarHBondContact O-N 2.89Å; I373-L375 PolarHBondContact O-N 3.26Å; L375-I378 HydrophobicContact CD1-CD1 4.47Å; L375-I378 WeakPolarHBondContact O-CB 3.34Å; L375-I378 PolarHBondContact O-N 3.26Å; L375-N379 PolarHBondContact O-N 2.94Å
376A91.4Very high88.2Confident0 Ų021.7 Ų21.70%012%0.115CC..Hα-helixtrans-65.3-39174.500000112.3C336 W337 L340 G372 I373 N374 N379C336-A376 PolarHBondContact O-N 3.06Å; W337-A376 HydrophobicContact CD2-CB 4.15Å; W337-A376 HydrophobicContact CE3-CB 4.29Å; W337-A376 HydrophobicContact CH2-CB 3.94Å; W337-A376 HydrophobicContact CZ2-CB 3.91Å; W337-A376 HydrophobicContact CZ3-CB 4.2Å; L340-A376 HydrophobicContact CD2-CB 4.16Å; G372-A376 WeakPolarHBondContact O-CB 3.2Å; G372-A376 PolarHBondContact O-N 3.03Å; I373-A376 PolarHBondContact O-N 3.15Å; N374-A376 VanDerWaalsContact C-N 3.33Å; A376-N379 VanDerWaalsContact O-CB 3.31Å; A376-N379 WeakPolarHBondContact O-CB 3.38Å; A376-N379 PolarHBondContact O-N 2.97Å
377T90.5Very high88.2Confident0 Ų020.4 Ų20.40%011%0.108CC..Hα-helixtrans-69.1-35.5174.655.90000112.1Y147 D151 I152 I373 N374 N379 S380 C381Y147-T377 HydrophobicContact CD1-CG2 4.33Å; Y147-T377 HydrophobicContact CE1-CG2 3.57Å; D151-T377 WeakPolarHBondContact OD2-CG2 3.34Å; I152-T377 HydrophobicContact CD1-CG2 4.46Å; I152-T377 HydrophobicContact CG1-CG2 3.97Å; I373-T377 WeakPolarHBondContact O-CG2 3.49Å; I373-T377 PolarHBondContact O-N 3.03Å; I373-T377 PolarHBondContact O-OG1 3.36Å; N374-T377 WeakPolarHBondContact CA-OG1 3.37Å; N374-T377 PolarHBondContact O-N 3.36Å; N374-T377 PolarHBondContact O-OG1 3.33Å; T377-N379 VanDerWaalsContact C-N 3.26Å; T377-N379 PolarHBondContact O-N 3.37Å; T377-S380 WeakPolarHBondContact O-CB 3.23Å; T377-S380 PolarHBondContact O-N 3Å; T377-S380 VanDerWaalsContact O-N 3.12Å; T377-C381 PolarHBondContact O-SG 2.04Å
378I91.4Very high88.2Confident45 Ų4521.4 Ų21.423%0.23111%0.108CC..Hα-helixtrans-57.5-38173.3-75.5164.6000111.5V108 N374 L375 S380 C381 I382V108-I378 HydrophobicContact CG1-CG1 4.34Å; V108-I378 HydrophobicContact CG2-CD1 4.3Å; V108-I378 HydrophobicContact CG2-CG1 3.53Å; N374-I378 WeakPolarHBondContact O-CB 3.16Å; N374-I378 WeakPolarHBondContact O-CD1 3.46Å; N374-I378 WeakPolarHBondContact O-CG1 3.16Å; N374-I378 PolarHBondContact O-N 3.04Å; L375-I378 HydrophobicContact CD1-CD1 4.47Å; L375-I378 WeakPolarHBondContact O-CB 3.34Å; L375-I378 PolarHBondContact O-N 3.26Å; I378-S380 PolarHBondContact O-N 2.83Å; I378-C381 WeakPolarHBondContact O-CA 3.16Å; I378-C381 WeakPolarHBondContact O-CB 3.2Å; I378-C381 PolarHBondContact O-N 2.64Å; I378-I382 HydrophobicContact CG2-CD1 3.42Å; I378-I382 VanDerWaalsContact CG2-CD1 3.42Å; I378-I382 HydrophobicContact CG2-CG1 3.87Å; I378-I382 WeakPolarHBondContact O-CG1 3.27Å; I378-I382 PolarHBondContact O-N 3.12Å
379N90.3Very high87.9Confident2 Ų226.2 Ų26.21%0.01113%0.128CC..Hα-helixtrans-53.3-41.8176.4-179.369.6000112.3F333 C336 W337 L375 A376 T377 C381 I382F333-N379 VanDerWaalsContact CA-OD1 3.29Å; F333-N379 WeakPolarHBondContact CA-OD1 3.17Å; C336-N379 HydrophobicContact CB-CB 3.73Å; W337-N379 PolarHBondContact NE1-ND2 3.42Å; L375-N379 PolarHBondContact O-N 2.94Å; A376-N379 VanDerWaalsContact O-CB 3.31Å; A376-N379 WeakPolarHBondContact O-CB 3.38Å; A376-N379 PolarHBondContact O-N 2.97Å; T377-N379 VanDerWaalsContact C-N 3.26Å; T377-N379 PolarHBondContact O-N 3.37Å; N379-C381 PolarHBondContact O-N 3.28Å; N379-I382 PolarHBondContact O-N 3.04Å
380S90Very high87.2Confident2 Ų227.1 Ų27.11%0.01414%0.135CC..Hα-helixtrans-68.1-21.6179.2-50.20000112.8N116 T377 I378N116-S380 PolarHBondContact ND2-O 3.3Å; T377-S380 WeakPolarHBondContact O-CB 3.23Å; T377-S380 PolarHBondContact O-N 3Å; T377-S380 VanDerWaalsContact O-N 3.12Å; I378-S380 PolarHBondContact O-N 2.83Å
381C89.8Confident86.7Confident6 Ų627.7 Ų27.74%0.04114%0.141CC..Hα-helixtrans-93.7-24.5-179.7-56.50000112.7V108 G112 T377 I378 N379 N383V108-C381 WeakPolarHBondContact CG1-SG 3.39Å; V108-C381 PolarHBondContact O-SG 3.12Å; G112-C381 WeakPolarHBondContact CA-SG 3.49Å; T377-C381 PolarHBondContact O-SG 2.04Å; I378-C381 WeakPolarHBondContact O-CA 3.16Å; I378-C381 WeakPolarHBondContact O-CB 3.2Å; I378-C381 PolarHBondContact O-N 2.64Å; N379-C381 PolarHBondContact O-N 3.28Å; C381-N383 VanDerWaalsContact C-N 3.33Å
382I88Confident86.1Confident38 Ų3834.3 Ų34.320%0.19517%0.168CC..Hα-helixtrans-73.9-26.7-178.6-72.5174.1000111.6I332 I378 N379 I385 I386I332-I382 HydrophobicContact CD1-CG2 4.29Å; I332-I382 HydrophobicContact CG2-CB 4.48Å; I332-I382 HydrophobicContact CG2-CD1 3.74Å; I332-I382 HydrophobicContact CG2-CG2 4.07Å; I378-I382 HydrophobicContact CG2-CD1 3.42Å; I378-I382 VanDerWaalsContact CG2-CD1 3.42Å; I378-I382 HydrophobicContact CG2-CG1 3.87Å; I378-I382 WeakPolarHBondContact O-CG1 3.27Å; I378-I382 PolarHBondContact O-N 3.12Å; N379-I382 PolarHBondContact O-N 3.04Å; I382-I385 WeakPolarHBondContact O-CA 3.38Å; I382-I385 WeakPolarHBondContact O-CB 3.48Å; I382-I385 PolarHBondContact O-N 3.22Å; I382-I386 HydrophobicContact CG2-CD1 3.3Å; I382-I386 HydrophobicContact CG2-CG1 3.57Å; I382-I386 PolarHBondContact O-N 2.95Å
383N84.8Confident85.5Confident7 Ų739.1 Ų39.14%0.03719%0.189CC..Hα-helixtrans-53.8-53.2-175.8-69.6-23.7000113.5D144 C381 I385 I386 L387D144-N383 PolarHBondContact OD2-ND2 3.13Å; C381-N383 VanDerWaalsContact C-N 3.33Å; N383-I385 VanDerWaalsContact C-N 3.32Å; N383-I385 PolarHBondContact O-N 3.06Å; N383-I386 PolarHBondContact O-N 3.04Å; N383-L387 WeakPolarHBondContact O-CG 3.49Å; N383-L387 PolarHBondContact O-N 3.33Å; N383-L387 VanDerWaalsContact O-N 3.14Å
384P86.7Confident85.1Confident5 Ų538.7 Ų38.73%0.03219%0.187CC..Hα-helixtrans-59.6-37.6172.9-24.833.4000114.1N116 L119 L387 Y388 F398N116-P384 HydrophobicContact CB-CG 4.47Å; N116-P384 WeakPolarHBondContact OD1-CD 3.41Å; N116-P384 VanDerWaalsContact OD1-CG 3.26Å; N116-P384 WeakPolarHBondContact OD1-CG 3.24Å; L119-P384 HydrophobicContact CD2-CG 4.25Å; P384-L387 PolarHBondContact O-N 3.18Å; P384-Y388 WeakPolarHBondContact O-CB 3.47Å; P384-Y388 PolarHBondContact O-N 3.36Å; P384-F398 HydrophobicContact CB-CZ 4.07Å
385I87.9Confident84.8Confident71 Ų7142 Ų4236%0.36420%0.201SC..Hα-helixtrans-64.3-45.8-178.9-58.2175.7000109.9V111 I382 N383 L387 Y388 F389V111-I385 HydrophobicContact CG1-CD1 4.3Å; I382-I385 WeakPolarHBondContact O-CA 3.38Å; I382-I385 WeakPolarHBondContact O-CB 3.48Å; I382-I385 PolarHBondContact O-N 3.22Å; N383-I385 VanDerWaalsContact C-N 3.32Å; N383-I385 PolarHBondContact O-N 3.06Å; I385-L387 PolarHBondContact O-N 3.16Å; I385-Y388 WeakPolarHBondContact O-CB 3.17Å; I385-Y388 PolarHBondContact O-N 3.39Å; I385-F389 HydrophobicContact CG2-CD2 3.87Å; I385-F389 HydrophobicContact CG2-CE2 3.68Å; I385-F389 WeakPolarHBondContact O-CD2 3.47Å; I385-F389 PolarHBondContact O-N 3.06Å; I385-F389 VanDerWaalsContact O-N 3.15Å
386I82.8Confident84.4Confident14 Ų1445.7 Ų45.77%0.07222%0.221CC..Hα-helixtrans-61.9-46.7176.6-70.3170.4000110.2L329 I332 I382 N383 Y388 F389 V390L329-I386 HydrophobicContact CD1-CG2 4.45Å; L329-I386 HydrophobicContact CD2-CB 4.1Å; L329-I386 HydrophobicContact CD2-CD1 3.31Å; L329-I386 HydrophobicContact CD2-CG1 4.31Å; L329-I386 HydrophobicContact CD2-CG2 3.98Å; L329-I386 HydrophobicContact CG-CD1 3.96Å; L329-I386 HydrophobicContact CG-CG2 4.02Å; I332-I386 HydrophobicContact CD1-CD1 3.56Å; I332-I386 HydrophobicContact CD1-CG1 4.4Å; I382-I386 HydrophobicContact CG2-CD1 3.3Å; I382-I386 HydrophobicContact CG2-CG1 3.57Å; I382-I386 PolarHBondContact O-N 2.95Å; N383-I386 PolarHBondContact O-N 3.04Å; I386-Y388 PolarHBondContact O-N 3.25Å; I386-F389 PolarHBondContact O-N 2.92Å; I386-F389 VanDerWaalsContact O-N 3.09Å; I386-V390 HydrophobicContact CG2-CG2 3.68Å; I386-V390 VanDerWaalsContact O-CB 3.28Å; I386-V390 WeakPolarHBondContact O-CB 3.44Å; I386-V390 VanDerWaalsContact O-CG2 3.23Å; I386-V390 WeakPolarHBondContact O-CG2 3.5Å; I386-V390 PolarHBondContact O-N 2.97Å
387L82.5Confident84.1Confident25 Ų2546.8 Ų46.813%0.13123%0.228CC..Hα-helixtrans-61-35.9179.6-69.1173.1000112.2L119 I137 N383 P384 I385 S391 F394L119-L387 HydrophobicContact CD1-CD1 4.01Å; L119-L387 HydrophobicContact CD2-CD1 3.69Å; I137-L387 HydrophobicContact CD1-CD1 4.38Å; I137-L387 HydrophobicContact CD1-CD2 4.06Å; I137-L387 HydrophobicContact CG2-CD1 3.51Å; N383-L387 WeakPolarHBondContact O-CG 3.49Å; N383-L387 PolarHBondContact O-N 3.33Å; N383-L387 VanDerWaalsContact O-N 3.14Å; P384-L387 PolarHBondContact O-N 3.18Å; I385-L387 PolarHBondContact O-N 3.16Å; L387-S391 WeakPolarHBondContact O-CB 3.37Å; L387-S391 PolarHBondContact O-N 3.46Å; L387-F394 HydrophobicContact CB-CD2 4.47Å; L387-F394 HydrophobicContact CB-CG 4.47Å; L387-F394 HydrophobicContact CD2-CD2 4.48Å; L387-F394 HydrophobicContact CD2-CE2 4.45Å
388Y85.1Confident83.8Confident64 Ų6447.2 Ų47.225%0.25123%0.23SC..Hα-helixtrans-61.8-41.9173.3176.7-95.4000112.8P384 I385 I386 K395 F398 K399P384-Y388 WeakPolarHBondContact O-CB 3.47Å; P384-Y388 PolarHBondContact O-N 3.36Å; I385-Y388 WeakPolarHBondContact O-CB 3.17Å; I385-Y388 PolarHBondContact O-N 3.39Å; I386-Y388 PolarHBondContact O-N 3.25Å; Y388-K395 HydrophobicContact CD2-CB 4.32Å; Y388-K395 HydrophobicContact CD2-CG 4.01Å; Y388-K395 HydrophobicContact CE1-CG 4.36Å; Y388-K395 HydrophobicContact CE2-CB 4.33Å; Y388-K395 HydrophobicContact CE2-CG 3.59Å; Y388-K395 VanDerWaalsContact O-CB 3.32Å; Y388-K395 WeakPolarHBondContact O-CB 3.06Å; Y388-F398 HydrophobicContact CD2-CB 3.61Å; Y388-F398 HydrophobicContact CD2-CD2 4.01Å; Y388-F398 HydrophobicContact CD2-CG 4.02Å; Y388-F398 HydrophobicContact CE2-CB 3.99Å; Y388-K399 HydrophobicContact CE2-CG 4.27Å; Y388-K399 WeakPolarHBondContact OH-CE 3.38Å
389F78.5Confident83.5Confident116 Ų11649.7 Ų49.751%0.50924%0.239SC..Hα-helixtrans-81.4-34.5-179.4-75.3-68.1000113.6M1 I385 I386M1-F389 HydrophobicContact CE-CB 3.59Å; M1-F389 HydrophobicContact CE-CD2 3.95Å; M1-F389 HydrophobicContact CE-CG 3.79Å; M1-F389 HydrophobicContact SD-CB 3.84Å; M1-F389 HydrophobicContact SD-CD1 4.44Å; M1-F389 HydrophobicContact SD-CG 4.16Å; I385-F389 HydrophobicContact CG2-CD2 3.87Å; I385-F389 HydrophobicContact CG2-CE2 3.68Å; I385-F389 WeakPolarHBondContact O-CD2 3.47Å; I385-F389 PolarHBondContact O-N 3.06Å; I385-F389 VanDerWaalsContact O-N 3.15Å; I386-F389 PolarHBondContact O-N 2.92Å; I386-F389 VanDerWaalsContact O-N 3.09Å
390V72.9Confident83.2Confident63 Ų6353 Ų5338%0.38226%0.263SS..Hα-helixtrans-80-41-174.8167.70000111.7A325 I386A325-V390 HydrophobicContact CB-CB 4.04Å; A325-V390 HydrophobicContact CB-CG1 3.31Å; A325-V390 HydrophobicContact CB-CG2 3.54Å; I386-V390 HydrophobicContact CG2-CG2 3.68Å; I386-V390 VanDerWaalsContact O-CB 3.28Å; I386-V390 WeakPolarHBondContact O-CB 3.44Å; I386-V390 VanDerWaalsContact O-CG2 3.23Å; I386-V390 WeakPolarHBondContact O-CG2 3.5Å; I386-V390 PolarHBondContact O-N 2.97Å
391S76.2Confident82.7Confident32 Ų3254.3 Ų54.322%0.22427%0.271CS..  trans-110.9113.9-171.9174.30000111.7L387 K393 F394 K395L387-S391 WeakPolarHBondContact O-CB 3.37Å; L387-S391 PolarHBondContact O-N 3.46Å; S391-K393 PolarHBondContact O-N 2.93Å; S391-K393 PolarHBondContact OG-N 3.28Å; S391-F394 PolarHBondContact O-N 3.42Å; S391-F394 WeakPolarHBondContact OG-CD2 3.17Å; S391-F394 PolarHBondContact OG-N 3.15Å; S391-K395 WeakPolarHBondContact O-CB 3.2Å; S391-K395 PolarHBondContact O-N 2.77Å
392K75.3Confident82.3Confident181 Ų18158.9 Ų58.979%0.78730%0.295SS*.Hα-helixtrans-53.5-36172.5-67.4-176.7-179.2179.20112.1N396K392-N396 VanDerWaalsContact O-CG 3.24Å; K392-N396 PolarHBondContact O-N 2.73Å; K392-N396 PolarHBondContact O-OD1 3.37Å
393K78.7Confident81.5Confident102 Ų10260.1 Ų60.144%0.44331%0.306SS..Hα-helixtrans-68.1-47.7179.8-164.2176.7-176.7-167.30111.5C128 M129 S391 C397C128-K393 PolarHBondContact O-NZ 2.82Å; M129-K393 HydrophobicContact CE-CD 4.45Å; M129-K393 HydrophobicContact CE-CG 4.39Å; M129-K393 HydrophobicContact SD-CD 3.38Å; M129-K393 WeakPolarHBondContact SD-CD 3.26Å; M129-K393 WeakPolarHBondContact SD-CE 3.33Å; M129-K393 HydrophobicContact SD-CG 3.71Å; M129-K393 PolarHBondContact SD-NZ 2.87Å; S391-K393 PolarHBondContact O-N 2.93Å; S391-K393 PolarHBondContact OG-N 3.28Å; K393-C397 PolarHBondContact O-N 3.4Å; K393-C397 PolarHBondContact O-SG 3.27Å
394F82.1Confident80.1Confident8 Ų864.4 Ų64.44%0.03534%0.336CS..Hα-helixtrans-64.9-43.6174.3-79.3-71.8000111.2L119 I122 I123 M129 N134 I137 L387 S391 N396 C397 F398L119-F394 HydrophobicContact CD1-CD1 3.87Å; L119-F394 HydrophobicContact CD1-CE1 3.6Å; L119-F394 HydrophobicContact CD1-CZ 4.46Å; I122-F394 HydrophobicContact CG2-CD1 4.43Å; I123-F394 HydrophobicContact CD1-CE1 4.31Å; I123-F394 HydrophobicContact CG1-CE1 4.11Å; M129-F394 HydrophobicContact CE-CD1 3.45Å; M129-F394 VanDerWaalsContact CE-CD1 3.45Å; M129-F394 HydrophobicContact CE-CD2 4.02Å; M129-F394 HydrophobicContact CE-CE1 3.17Å; M129-F394 HydrophobicContact CE-CE2 3.77Å; M129-F394 HydrophobicContact CE-CG 3.87Å; M129-F394 HydrophobicContact CE-CZ 3.34Å; N134-F394 WeakPolarHBondContact OD1-CZ 3.41Å; I137-F394 HydrophobicContact CD1-CE2 4.21Å; I137-F394 HydrophobicContact CD1-CZ 4.2Å; L387-F394 HydrophobicContact CB-CD2 4.47Å; L387-F394 HydrophobicContact CB-CG 4.47Å; L387-F394 HydrophobicContact CD2-CD2 4.48Å; L387-F394 HydrophobicContact CD2-CE2 4.45Å; S391-F394 PolarHBondContact O-N 3.42Å; S391-F394 WeakPolarHBondContact OG-CD2 3.17Å; S391-F394 PolarHBondContact OG-N 3.15Å; F394-N396 VanDerWaalsContact C-N 3.32Å; F394-N396 PolarHBondContact O-N 3.37Å; F394-C397 PolarHBondContact O-N 3.07Å; F394-C397 VanDerWaalsContact O-N 3.1Å; F394-F398 HydrophobicContact CB-CD2 4.19Å; F394-F398 HydrophobicContact CB-CE2 4.19Å; F394-F398 HydrophobicContact CD1-CE2 4.43Å; F394-F398 WeakPolarHBondContact O-CD2 3.38Å; F394-F398 PolarHBondContact O-N 3.43Å
395K84.6Confident78.1Confident75 Ų7576.4 Ų76.433%0.32638%0.38SS..Hα-helixtrans-50.4-49.8175.9-169.6179.2179.1175.10112.7Y388 S391 F398 K399Y388-K395 HydrophobicContact CD2-CB 4.32Å; Y388-K395 HydrophobicContact CD2-CG 4.01Å; Y388-K395 HydrophobicContact CE1-CG 4.36Å; Y388-K395 HydrophobicContact CE2-CB 4.33Å; Y388-K395 HydrophobicContact CE2-CG 3.59Å; Y388-K395 VanDerWaalsContact O-CB 3.32Å; Y388-K395 WeakPolarHBondContact O-CB 3.06Å; S391-K395 WeakPolarHBondContact O-CB 3.2Å; S391-K395 PolarHBondContact O-N 2.77Å; K395-F398 PolarHBondContact O-N 3.42Å; K395-K399 WeakPolarHBondContact O-CG 3.31Å; K395-K399 PolarHBondContact O-N 3.06Å
396N83.5Confident75.8Confident103 Ų10378.4 Ų78.455%0.55140%0.399SS*.Hα-helixtrans-66.2-39.3-179.5-69.3-5.6000111.7K392 F394 K399 S400K392-N396 VanDerWaalsContact O-CG 3.24Å; K392-N396 PolarHBondContact O-N 2.73Å; K392-N396 PolarHBondContact O-OD1 3.37Å; F394-N396 VanDerWaalsContact C-N 3.32Å; F394-N396 PolarHBondContact O-N 3.37Å; N396-K399 PolarHBondContact O-N 3.33Å; N396-S400 WeakPolarHBondContact O-CB 3.12Å; N396-S400 PolarHBondContact O-N 3.38Å
397C84Confident73.7Confident23 Ų2384.8 Ų84.816%0.15542%0.423CS..Hα-helixtrans-67.1-40.6176.1-61.60000112.3I122 K393 F394 S400 C401I122-C397 HydrophobicContact CB-CB 4.37Å; I122-C397 HydrophobicContact CD1-CB 3.9Å; I122-C397 HydrophobicContact CG1-CB 3.99Å; I122-C397 HydrophobicContact CG2-CB 3.46Å; I122-C397 VanDerWaalsContact CG2-CB 3.46Å; K393-C397 PolarHBondContact O-N 3.4Å; K393-C397 PolarHBondContact O-SG 3.27Å; F394-C397 PolarHBondContact O-N 3.07Å; F394-C397 VanDerWaalsContact O-N 3.1Å; C397-S400 PolarHBondContact O-N 3.04Å; C397-C401 WeakPolarHBondContact O-CB 3.34Å; C397-C401 PolarHBondContact O-N 3.07Å
398F85.1Confident71.5Confident9 Ų989 Ų894%0.03946%0.455CS..Hα-helixtrans-62.7-44.5174.5-85.5-69000111.6T118 L119 I122 P384 Y388 F394 K395 S400 C401 L402T118-F398 HydrophobicContact CG2-CD1 3.67Å; T118-F398 HydrophobicContact CG2-CE1 3.74Å; L119-F398 HydrophobicContact CB-CZ 4.03Å; L119-F398 HydrophobicContact CD1-CE2 4.29Å; L119-F398 HydrophobicContact CD1-CZ 4Å; I122-F398 HydrophobicContact CD1-CB 4.33Å; I122-F398 HydrophobicContact CD1-CD1 3.64Å; I122-F398 HydrophobicContact CD1-CD2 4.05Å; I122-F398 HydrophobicContact CD1-CE1 3.87Å; I122-F398 HydrophobicContact CD1-CE2 4.25Å; I122-F398 HydrophobicContact CD1-CG 3.72Å; I122-F398 HydrophobicContact CD1-CZ 4.17Å; P384-F398 HydrophobicContact CB-CZ 4.07Å; Y388-F398 HydrophobicContact CD2-CB 3.61Å; Y388-F398 HydrophobicContact CD2-CD2 4.01Å; Y388-F398 HydrophobicContact CD2-CG 4.02Å; Y388-F398 HydrophobicContact CE2-CB 3.99Å; F394-F398 HydrophobicContact CB-CD2 4.19Å; F394-F398 HydrophobicContact CB-CE2 4.19Å; F394-F398 HydrophobicContact CD1-CE2 4.43Å; F394-F398 WeakPolarHBondContact O-CD2 3.38Å; F394-F398 PolarHBondContact O-N 3.43Å; K395-F398 PolarHBondContact O-N 3.42Å; F398-S400 VanDerWaalsContact C-N 3.35Å; F398-S400 PolarHBondContact O-N 3.46Å; F398-C401 PolarHBondContact O-N 2.95Å; F398-L402 HydrophobicContact CD1-CD1 4.18Å; F398-L402 VanDerWaalsContact O-CB 3.31Å; F398-L402 WeakPolarHBondContact O-CB 3.42Å; F398-L402 WeakPolarHBondContact O-CG 3.3Å; F398-L402 PolarHBondContact O-N 3.02Å
399K85.3Confident69.3Low98 Ų9892.9 Ų92.943%0.42648%0.48SS..Hα-helixtrans-60.7-44174.1-76.3-173.4171.2-162.20111.8Y388 K395 N396 C403Y388-K399 HydrophobicContact CE2-CG 4.27Å; Y388-K399 WeakPolarHBondContact OH-CE 3.38Å; K395-K399 WeakPolarHBondContact O-CG 3.31Å; K395-K399 PolarHBondContact O-N 3.06Å; N396-K399 PolarHBondContact O-N 3.33Å; K399-C403 VanDerWaalsContact O-CA 3.28Å; K399-C403 WeakPolarHBondContact O-CA 2.97Å; K399-C403 WeakPolarHBondContact O-CB 3.37Å; K399-C403 PolarHBondContact O-N 3.17Å
400S82.8Confident67Low72 Ų7294.8 Ų94.850%0.50350%0.496SS..Hα-helixtrans-62-44.5176.4177.80000111.3N396 C397 F398 C404N396-S400 WeakPolarHBondContact O-CB 3.12Å; N396-S400 PolarHBondContact O-N 3.38Å; C397-S400 PolarHBondContact O-N 3.04Å; F398-S400 VanDerWaalsContact C-N 3.35Å; F398-S400 PolarHBondContact O-N 3.46Å; S400-C404 PolarHBondContact O-SG 3.32Å
401C81Confident65.3Low28 Ų2899 Ų9919%0.18951%0.511CS..Hα-helixtrans-76.6-33.5-175.9-165.10000114.3T118 I122 C397 F398T118-C401 HydrophobicContact CG2-CB 4.12Å; I122-C401 HydrophobicContact CG1-CB 4.41Å; C397-C401 WeakPolarHBondContact O-CB 3.34Å; C397-C401 PolarHBondContact O-N 3.07Å; F398-C401 PolarHBondContact O-N 2.95Å
402L79.8Confident63.4Low103 Ų103105 Ų10554%0.53954%0.54SS..Hα-helixtrans-97-29-176.8-64.4172.4000113.1V114 T118 F398V114-L402 HydrophobicContact CG1-CD2 4.36Å; T118-L402 HydrophobicContact CG2-CD2 4.22Å; T118-L402 HydrophobicContact CG2-CG 4.22Å; F398-L402 HydrophobicContact CD1-CD1 4.18Å; F398-L402 VanDerWaalsContact O-CB 3.31Å; F398-L402 WeakPolarHBondContact O-CB 3.42Å; F398-L402 WeakPolarHBondContact O-CG 3.3Å; F398-L402 PolarHBondContact O-N 3.02Å
403C71.8Confident61.2Low64 Ų64104.3 Ų104.343%0.43255%0.545SS..  trans-107.928.8-178.3-47.90000112.2K399 W405 C406K399-C403 VanDerWaalsContact O-CA 3.28Å; K399-C403 WeakPolarHBondContact O-CA 2.97Å; K399-C403 WeakPolarHBondContact O-CB 3.37Å; K399-C403 PolarHBondContact O-N 3.17Å; C403-W405 PolarHBondContact O-N 3.13Å; C403-C406 PolarHBondContact O-N 3.44Å
404C56.8Low59Low97 Ų97105 Ų10566%0.65556%0.563SS**THydrogen-bonded Turntrans-53.5-12.4174.5-98.10000114.1S400S400-C404 PolarHBondContact O-SG 3.32Å
405W44.5Very low56.6Low257 Ų257113 Ų11397%0.97360%0.604SS**THydrogen-bonded Turntrans-79.9-6.5169.8-97.4-36.6000115.7C403C403-W405 PolarHBondContact O-N 3.13Å
406C38.5Very low54Low112 Ų112112.4 Ų112.476%0.75762%0.619SS**SBendtrans-127.79.4-175.1-60.70000115C403C403-C406 PolarHBondContact O-N 3.44Å
407Y39.6Very low51.6Low148 Ų148115.1 Ų115.158%0.5863%0.633SS**  trans-126.463.5-178.2-147.9-94.5000112.1Q411Y407-Q411 HydrophobicContact CE1-CG 4.28Å; Y407-Q411 WeakPolarHBondContact OH-CG 3.3Å
408S36.2Very low49.1Very low114 Ų114120.5 Ų120.580%0.79767%0.665SS**SBendtrans-126.6101.2149.6-78.40000105.7
409D37.5Very low46.6Very low146 Ų146127.6 Ų127.678%0.78170%0.703SS**SBendtrans170.6-10.8132.3-103.1-23.3000117.6
410N31.2Very low43.9Very low155 Ų155125.8 Ų125.883%0.82971%0.712SS**THydrogen-bonded Turntrans-10928.6-166.9-78.3-11.2000117.6
411Q36.6Very low41.7Very low151 Ų151129.9 Ų129.971%0.70673%0.734SS**THydrogen-bonded Turntrans-116.815.2175-82.2-88.422.400114.5Y407Y407-Q411 HydrophobicContact CE1-CG 4.28Å; Y407-Q411 WeakPolarHBondContact OH-CG 3.3Å
412L35.8Very low39.1Very low158 Ų158133.5 Ų133.583%0.82776%0.76SS**SBendtrans-114.940177.4-150.686.3000112.9
413N30.8Very low36.9Very low168 Ų168135.6 Ų135.690%0.89878%0.776SS**SBendtrans-151.838.1174.9-98.9-17.3000115.1
414S30.9Very low34.8Very low117 Ų117140.5 Ų140.582%0.81879%0.793SS**  trans-151.170.6163.7-148.90000111.7G416S414-G416 PolarHBondContact O-N 3.47Å
415I33.3Very low33.4Very low175 Ų175139.1 Ų139.190%0.89778%0.784SS**  trans-91.486.2161.3-61.1177.9000106.5
416G29.5Very low32.4Very low62 Ų62135.9 Ų135.964%0.63978%0.777SS**  trans-91.5115158.500000108.5S414 V418S414-G416 PolarHBondContact O-N 3.47Å; G416-V418 PolarHBondContact O-N 3.5Å
417L32.9Very low31.9Very low161 Ų161135.6 Ų135.684%0.84378%0.776SS**  trans-58.1111.6178.1-17484.2000111.3
418V31.5Very low31.3Very low136 Ų136133.2 Ų133.282%0.82478%0.778SS**  trans-142.1118.6159.9-173.30000110G416G416-V418 PolarHBondContact O-N 3.5Å
419N32.1Very low30.9Very low157 Ų157136.4 Ų136.484%0.8478%0.781SS**  trans-57.9130.5170.9-76.4-24.5000111.3
420G28.8Very low30.7Very low60 Ų60134.8 Ų134.862%0.61978%0.778SS**  trans166.6111171.500000112S422G420-S422 PolarHBondContact O-N 2.91Å
421T36.6Very low30.6Very low159 Ų159135.1 Ų135.198%0.97578%0.78SS**  trans-41.3104.4173.926.40000112.8
422S27.4Very low30.2Very low103 Ų103135.8 Ų135.872%0.7279%0.788SS**  trans-139.9124.1161.160.80000109G420 Q424G420-S422 PolarHBondContact O-N 2.91Å; S422-Q424 PolarHBondContact O-N 3.46Å
423V32.5Very low30Very low147 Ų147136.1 Ų136.189%0.89179%0.79SS**  trans-68.1100179.7175.60000108.2
424Q27Very low29.9Very low168 Ų168136.6 Ų136.679%0.78579%0.786SS**  trans-76.9130.7178.2-152.9170.91300109.6S422 K426S422-Q424 PolarHBondContact O-N 3.46Å; Q424-K426 PolarHBondContact O-N 3.05Å
425C27.6Very low29.9Very low68 Ų68136.2 Ų136.246%0.45978%0.78SS.*  trans-71.993.1177.9-1410000109.4C128C128-C425 HydrophobicContact CB-CB 4.12Å; C128-C425 WeakPolarHBondContact CB-SG 3.32Å; C128-C425 WeakPolarHBondContact SG-CB 3.18Å; C128-C425 CovalentContact SG-SG 2.03Å; C128-C425 PolarHBondContact SG-SG 3.44Å
426K23.6Very low29.7Very low189 Ų189135.6 Ų135.682%0.82278%0.778SS**PPolyproline II helixtrans-75.3129.8167-81.7-175.6174.8-176.40109.8Q424Q424-K426 PolarHBondContact O-N 3.05Å
427S27.8Very low29.7Very low105 Ų105141.8 Ų141.873%0.73479%0.787SS**PPolyproline II helixtrans-64.2149.2165.6-163.50000109.5E429S427-E429 PolarHBondContact O-N 3.47Å
428P27.7Very low29.6Very low99 Ų99139.1 Ų139.164%0.64378%0.782SS**PPolyproline II helixtrans-72.1118.9173.80.716.1000109.3
429E29Very low29.6Very low181 Ų181139.7 Ų139.785%0.84678%0.779SS**PPolyproline II helixtrans-67.2146.7163-85.6173.4128.200110.1S427S427-E429 PolarHBondContact O-N 3.47Å
430P32.3Very low29.6Very low112 Ų112144 Ų14473%0.72778%0.783SS**PPolyproline II helixtrans-74.3131175.429.6-29.3000110.4N432P430-N432 PolarHBondContact O-N 3.24Å; P430-N432 VanDerWaalsContact O-N 3.13Å
431N29.6Very low29.7Very low161 Ų161149.9 Ų149.986%0.86179%0.792SS**  trans-58110.1177-72.5-24.5000111.4
432N27.2Very low29.5Very low165 Ų165149.2 Ų149.288%0.88278%0.783SS**  trans-91.4108.4157.7-83.9-22.3000109P430 H434P430-N432 PolarHBondContact O-N 3.24Å; P430-N432 VanDerWaalsContact O-N 3.13Å; N432-H434 PolarHBondContact O-N 3.33Å
433L31.4Very low29.8Very low165 Ų165149.5 Ų149.586%0.86479%0.785SS**  trans-81.7101.9172.7-166.383.4000108.1
434H28.7Very low29.8Very low178 Ų178153.7 Ų153.782%0.82480%0.802SS**  trans-155.197.3154.1-116-58.1000112.2N432N432-H434 PolarHBondContact O-N 3.33Å
435T30.9Very low30Very low110 Ų110153 Ų15368%0.67580%0.803SS**  trans41100.2135.7-23.20000119.2
436D28.9Very low30.1Very low162 Ų162157.5 Ų157.587%0.86682%0.821SS**  trans-67.4122155-159.5-5.1000110.2
437K31.1Very low30.5Very low192 Ų192155.7 Ų155.784%0.83582%0.821SS**  trans-168.395.2164.1-109.7-177.5-172.5-178.60111.1
438S29.9Very low30.6Very low105 Ų105158.7 Ų158.773%0.73483%0.826SS**  trans-16996.1138.353.50000108.8
439I32.5Very low30.8Very low148 Ų148162.4 Ų162.476%0.75984%0.838SS**  56.892.897.8-58.2176.4000112.3
440R32.1Very low30.9Very low246 Ų246161.2 Ų161.293%0.92884%0.837SS**  trans-60.7121157.4-166.9-179.9-164.6-179.63.7109.5
441K30.9Very low30.8Very low185 Ų185164.7 Ų164.780%0.80485%0.845SS**  trans-143.9112.3160.9-103.6-175.9177.3-179.60110.7
442N30.6Very low30.9Very low145 Ų145165 Ų16578%0.77584%0.844SS**  trans24.8139.4146.7-61.6-5.4000123.2
443S34.9Very low31.2Very low109 Ų109165 Ų16576%0.76284%0.84SS**  trans64.6127.4142.7-65.80000116.3
444N32.8Very low31.2Very low235 Ų235165 Ų165100%1.25784%0.838SS**  cis-148.5032.1-90.1-23.8000110.8

Retrieved 444 of 444 residues in 511.8 ms (Link to these results)

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