A0A087XTA2_POEFO Loading...

Serine/threonine kinase 32A

AlphaFold DB , UniProt , Accession A0A087XTA2, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 404 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M38Very low32.7Very low248 Ų248138.6 Ų138.6100%1.22283%0.831SS**  0108.10-75.5-165.4-106.800107.6
2G33Very low32.8Very low76 Ų76136.9 Ų136.978%0.78482%0.823SS**  trans-85.1155.5179.600000111.7
3L30.4Very low33.2Very low174 Ų174134.9 Ų134.991%0.91181%0.805SS**  trans-154.588.5147.4-94.9169.6000106.1Q5L3-Q5 PolarHBondContact O-N 3.21Å
4G27.1Very low33.7Very low78 Ų78137.3 Ų137.380%0.80481%0.812SS**  trans-68.9115.5169.400000109.3S6G4-S6 VanDerWaalsContact C-N 3.34Å; G4-S6 PolarHBondContact O-N 3.23Å; G4-S6 VanDerWaalsContact O-N 3.09Å
5Q31.5Very low35.1Very low192 Ų192133.1 Ų133.190%0.89779%0.788SS**  trans-74.793.9164-75.7-176.8-2.300107.8L3 S7L3-Q5 PolarHBondContact O-N 3.21Å; Q5-S7 PolarHBondContact O-N 3.29Å
6S30.4Very low37Very low97 Ų97133.8 Ų133.868%0.67879%0.787SS**  trans-68.397.5165.2-179.40000107.8G4 K8G4-S6 VanDerWaalsContact C-N 3.34Å; G4-S6 PolarHBondContact O-N 3.23Å; G4-S6 VanDerWaalsContact O-N 3.09Å; S6-K8 PolarHBondContact O-N 3.31Å
7S35.7Very low39.8Very low112 Ų112132.2 Ų132.278%0.78377%0.77SS**  trans-66.485.1160.2540000107.7Q5 T9Q5-S7 PolarHBondContact O-N 3.29Å; S7-T9 PolarHBondContact O-N 3.05Å
8K31.7Very low42.7Very low182 Ų182125.8 Ų125.879%0.79173%0.733SS**  trans-66.2102.7165.2-74.9-171.7175.8-173.80107.1S6S6-K8 PolarHBondContact O-N 3.31Å
9T30.6Very low45.4Very low118 Ų118121.3 Ų121.372%0.72471%0.706SS**  trans-44.4132.8154.622.90000108S7 V11S7-T9 PolarHBondContact O-N 3.05Å; T9-V11 PolarHBondContact O-N 3.31Å; T9-V11 VanDerWaalsContact O-N 3.09Å
10P36.5Very low47.7Very low113 Ų113117.9 Ų117.973%0.73468%0.682SS**  trans-59.6123.117326.1-30.4000106.3T12P10-T12 VanDerWaalsContact C-N 3.28Å; P10-T12 PolarHBondContact O-N 3.46Å
11V34.2Very low49.7Very low135 Ų135115.5 Ų115.582%0.81867%0.667SS**  trans-58.599.9170.3179.40000105.3T9 D13T9-V11 PolarHBondContact O-N 3.31Å; T9-V11 VanDerWaalsContact O-N 3.09Å; V11-D13 PolarHBondContact O-N 2.89Å; V11-D13 VanDerWaalsContact O-N 3.15Å
12T35Very low52.4Low118 Ų118106.9 Ų106.972%0.72462%0.623SS**  trans-65.3107.3161.543.80000104.4P10 D14P10-T12 VanDerWaalsContact C-N 3.28Å; P10-T12 PolarHBondContact O-N 3.46Å; T12-D14 PolarHBondContact O-N 3.46Å
13D38Very low55.3Low111 Ų111103.6 Ų103.659%0.59459%0.587SS**  trans-55.9125.1171.2-141.6-11.1000106.5V11 T15V11-D13 PolarHBondContact O-N 2.89Å; V11-D13 VanDerWaalsContact O-N 3.15Å; D13-T15 PolarHBondContact O-N 3.25Å
14D40.2Very low58.3Low168 Ų16899 Ų9990%0.89856%0.561SS**SBendtrans-70.924.1-173.3-115.4-18.1000112.7T12T12-D14 PolarHBondContact O-N 3.46Å
15T53.8Low61.3Low75 Ų7596.4 Ų96.446%0.4653%0.529SS..SBendtrans-114.7115.9169.855.10000106.9D13 E17D13-T15 PolarHBondContact O-N 3.25Å; T15-E17 PolarHBondContact O-N 3.03Å
16D66Low64Low144 Ų14490.9 Ų90.977%0.7751%0.505SS*.  trans-60.412.9174.4-83.7-38.9000113.5K368D16-K368 VanDerWaalsContact C-NZ 3.28Å; D16-K368 WeakPolarHBondContact O-CE 3.46Å; D16-K368 PolarHBondContact O-NZ 3.27Å
17E84.9Confident66.6Low107 Ų10791.2 Ų91.250%0.549%0.492SS..  trans-87.7122.7-174.4-64.8-164.5163.100111.7T15 N19T15-E17 PolarHBondContact O-N 3.03Å; E17-N19 PolarHBondContact O-N 3.01Å
18V91.8Very high68.9Low16 Ų1686 Ų8610%0.09746%0.455CS..  trans-67.9125.21781720000109H22 F23 Y88 F90 N365V18-H22 HydrophobicContact CG1-CB 4.42Å; V18-F23 HydrophobicContact CG1-CE2 3.5Å; V18-F23 VanDerWaalsContact CG1-CE2 3.5Å; V18-F23 HydrophobicContact CG1-CZ 3.87Å; V18-Y88 HydrophobicContact CB-CD1 4.23Å; V18-Y88 HydrophobicContact CG1-CD1 3.96Å; V18-Y88 HydrophobicContact CG1-CE1 4.4Å; V18-Y88 HydrophobicContact CG1-CG 4.24Å; V18-Y88 HydrophobicContact CG2-CD1 4.28Å; V18-Y88 HydrophobicContact CG2-CE1 4.24Å; V18-F90 HydrophobicContact CG1-CD1 4.38Å; V18-F90 HydrophobicContact CG1-CE1 4.3Å; V18-F90 WeakPolarHBondContact O-CD1 3.3Å; V18-N365 VanDerWaalsContact CG2-ND2 3.33Å; V18-N365 WeakPolarHBondContact CG2-ND2 3.32Å
19N92.8Very high71.4Confident41 Ų4178.9 Ų78.922%0.21943%0.425CS..  trans-132.1-178.3179.568.435000111.5E17 D21 H22 F23E17-N19 PolarHBondContact O-N 3.01Å; N19-D21 VanDerWaalsContact C-N 3.25Å; N19-D21 PolarHBondContact O-N 3.18Å; N19-D21 WeakPolarHBondContact OD1-CB 3.32Å; N19-D21 PolarHBondContact OD1-N 3.34Å; N19-H22 PolarHBondContact N-ND1 2.87Å; N19-H22 VanDerWaalsContact N-ND1 3.17Å; N19-H22 WeakPolarHBondContact O-CB 3.47Å; N19-H22 PolarHBondContact O-N 3.15Å; N19-H22 VanDerWaalsContact O-N 3.09Å; N19-H22 PolarHBondContact O-ND1 3.49Å; N19-H22 PolarHBondContact OD1-CE1 3.47Å; N19-H22 PolarHBondContact OD1-ND1 3.19Å; N19-F23 WeakPolarHBondContact O-CD2 3.45Å
20F91.5Very high73.9Confident53 Ų5373.9 Ų73.923%0.23240%0.398CS..G310 helixtrans-56-35.2-176.5-174.1-98.3000113.9H22 F23 I25 M51 F90 F97F20-H22 PolarHBondContact O-N 2.87Å; F20-F23 PolarHBondContact O-N 3.26Å; F20-F23 VanDerWaalsContact O-N 3.1Å; F20-I25 HydrophobicContact CE2-CD1 3.8Å; F20-I25 HydrophobicContact CE2-CG1 4.19Å; F20-I25 HydrophobicContact CZ-CD1 3.93Å; F20-I25 HydrophobicContact CZ-CG1 3.79Å; F20-M51 HydrophobicContact CD2-SD 4.14Å; F20-M51 HydrophobicContact CE2-SD 4.06Å; F20-F90 VanDerWaalsContact CA-CE2 3.43Å; F20-F90 HydrophobicContact CB-CD2 4.38Å; F20-F90 HydrophobicContact CB-CE2 3.78Å; F20-F90 HydrophobicContact CD2-CE2 4.28Å; F20-F90 VanDerWaalsContact N-CE2 3.26Å; F20-F97 AromaticContact CD2-CD1 3.9Å; F20-F97 HydrophobicContact CD2-CD1 3.9Å; F20-F97 AromaticContact CD2-CE1 3.41Å; F20-F97 HydrophobicContact CD2-CE1 3.41Å; F20-F97 VanDerWaalsContact CD2-CE1 3.41Å; F20-F97 HydrophobicContact CD2-CE2 4.35Å; F20-F97 AromaticContact CD2-CZ 3.66Å; F20-F97 HydrophobicContact CD2-CZ 3.66Å; F20-F97 HydrophobicContact CE2-CD1 4.27Å; F20-F97 AromaticContact CE2-CE1 3.6Å; F20-F97 HydrophobicContact CE2-CE1 3.6Å; F20-F97 HydrophobicContact CE2-CZ 4.12Å; F20-F97 HydrophobicContact CG-CE1 4.46Å; F20-F97 HydrophobicContact CG-CZ 4.32Å
21D91.3Very high76Confident68 Ų6874.1 Ų74.136%0.36439%0.387SS..G310 helixtrans-68.8-17.1-178-67.3-52.7000113.9N19 F23 K43 K329N19-D21 VanDerWaalsContact C-N 3.25Å; N19-D21 PolarHBondContact O-N 3.18Å; N19-D21 WeakPolarHBondContact OD1-CB 3.32Å; N19-D21 PolarHBondContact OD1-N 3.34Å; D21-F23 PolarHBondContact O-N 3.05Å; D21-K43 WeakPolarHBondContact O-CD 3.29Å; D21-K43 WeakPolarHBondContact O-CE 3.37Å; D21-K43 PolarHBondContact O-NZ 2.97Å; D21-K329 WeakPolarHBondContact OD1-CE 3.4Å; D21-K329 IonicContact OD1-NZ 3.55Å; D21-K329 PolarHBondContact OD1-NZ 3.09Å; D21-K329 IonicContact OD2-NZ 2.65Å; D21-K329 PolarHBondContact OD2-NZ 3.01Å
22H93.9Very high78Confident66 Ų6669.4 Ų69.431%0.30637%0.366SS..G310 helixtrans-74.4-8.8175.8-64.982.9000112.5V18 N19 F20 K43V18-H22 HydrophobicContact CG1-CB 4.42Å; N19-H22 PolarHBondContact N-ND1 2.87Å; N19-H22 VanDerWaalsContact N-ND1 3.17Å; N19-H22 WeakPolarHBondContact O-CB 3.47Å; N19-H22 PolarHBondContact O-N 3.15Å; N19-H22 VanDerWaalsContact O-N 3.09Å; N19-H22 PolarHBondContact O-ND1 3.49Å; N19-H22 PolarHBondContact OD1-CE1 3.47Å; N19-H22 PolarHBondContact OD1-ND1 3.19Å; F20-H22 PolarHBondContact O-N 2.87Å; H22-K43 WeakPolarHBondContact O-CG 3.34Å; H22-K43 PolarHBondContact O-N 3.04Å
23F94.1Very high79.9Confident7 Ų768 Ų683%0.03136%0.36CS..EExtended strand (participates in β ladder)trans-114.3144-178.3-62.1-89.1000111.9V18 N19 F20 D21 V40 Q41 K42 Y49 M51 Y88 F90 V99V18-F23 HydrophobicContact CG1-CE2 3.5Å; V18-F23 VanDerWaalsContact CG1-CE2 3.5Å; V18-F23 HydrophobicContact CG1-CZ 3.87Å; N19-F23 WeakPolarHBondContact O-CD2 3.45Å; F20-F23 PolarHBondContact O-N 3.26Å; F20-F23 VanDerWaalsContact O-N 3.1Å; D21-F23 PolarHBondContact O-N 3.05Å; F23-V40 HydrophobicContact CB-CB 4.3Å; F23-V40 HydrophobicContact CD1-CB 4.28Å; F23-V40 HydrophobicContact CD1-CG2 3.75Å; F23-V40 HydrophobicContact CE1-CG2 4.38Å; F23-V40 HydrophobicContact CG-CG2 4.44Å; F23-Q41 CarbonylContact C-O 3.56Å; F23-Q41 WeakPolarHBondContact CA-O 3.4Å; F23-K42 HydrophobicContact CD1-CB 4.04Å; F23-K42 HydrophobicContact CD1-CG 4.26Å; F23-K42 HydrophobicContact CE1-CB 3.82Å; F23-K42 HydrophobicContact CE1-CD 4.44Å; F23-K42 HydrophobicContact CE1-CG 3.84Å; F23-K42 HydrophobicContact CZ-CG 4.17Å; F23-Y49 HydrophobicContact CE1-CD2 4.18Å; F23-M51 HydrophobicContact CB-CE 3.75Å; F23-M51 HydrophobicContact CD1-CE 4.1Å; F23-M51 HydrophobicContact CD2-CE 3.71Å; F23-M51 HydrophobicContact CE2-CE 4.35Å; F23-M51 HydrophobicContact CG-CE 3.57Å; F23-Y88 HydrophobicContact CE1-CD2 4.4Å; F23-Y88 HydrophobicContact CE1-CE2 4.37Å; F23-Y88 AromaticContact CZ-CD2 3.79Å; F23-Y88 HydrophobicContact CZ-CD2 3.79Å; F23-Y88 HydrophobicContact CZ-CE2 4.01Å; F23-Y88 HydrophobicContact CZ-CG 4.32Å; F23-F90 HydrophobicContact CD2-CE1 4.1Å; F23-F90 AromaticContact CD2-CZ 3.84Å; F23-F90 HydrophobicContact CD2-CZ 3.84Å; F23-F90 AromaticContact CE2-CE1 3.53Å; F23-F90 HydrophobicContact CE2-CE1 3.53Å; F23-F90 AromaticContact CE2-CZ 3.77Å; F23-F90 HydrophobicContact CE2-CZ 3.77Å; F23-F90 HydrophobicContact CZ-CE1 4.33Å; F23-V99 HydrophobicContact CE1-CG1 4.1Å; F23-V99 HydrophobicContact CE1-CG2 4.48Å; F23-V99 HydrophobicContact CE2-CG2 4.46Å; F23-V99 HydrophobicContact CZ-CG1 4.34Å; F23-V99 HydrophobicContact CZ-CG2 4.18Å
24Q92.6Very high81.9Confident77 Ų7764.1 Ų64.136%0.3634%0.339SS..EExtended strand (participates in β ladder)trans-100.6117.1165.2179.5176.6200108L26 V40 Q41Q24-L26 HydrophobicContact CG-CD2 4.05Å; Q24-V40 CarbonylContact O-C 3.57Å; Q24-V40 VanDerWaalsContact O-CA 3.28Å; Q24-V40 WeakPolarHBondContact O-CA 3.48Å; Q24-Q41 HydrophobicContact CB-CB 4.49Å; Q24-Q41 PolarHBondContact N-O 3.39Å; Q24-Q41 PolarHBondContact O-N 3.3Å
25I90.9Very high84Confident25 Ų2557 Ų5713%0.12831%0.305CS..EExtended strand (participates in β ladder)trans-73.5134173-49-55.4000108.9F20 C38 V40 M51F20-I25 HydrophobicContact CE2-CD1 3.8Å; F20-I25 HydrophobicContact CE2-CG1 4.19Å; F20-I25 HydrophobicContact CZ-CD1 3.93Å; F20-I25 HydrophobicContact CZ-CG1 3.79Å; I25-C38 HydrophobicContact CG2-CB 3.95Å; I25-V40 HydrophobicContact CD1-CB 4.33Å; I25-V40 HydrophobicContact CD1-CG1 3.34Å; I25-M51 HydrophobicContact CD1-CE 4.42Å; I25-M51 HydrophobicContact CD1-SD 3.98Å
26L88Confident85.5Confident76 Ų7655.4 Ų55.440%0.39829%0.292SS..EExtended strand (participates in β ladder)trans-112.3-65.2-177.6-62.9175.5000112.1Q24 I39 Q41 M48Q24-L26 HydrophobicContact CG-CD2 4.05Å; L26-I39 HydrophobicContact CB-CB 4.44Å; L26-I39 HydrophobicContact CB-CG2 4.27Å; L26-I39 HydrophobicContact CD1-CG2 4.05Å; L26-I39 PolarHBondContact N-O 3.31Å; L26-Q41 HydrophobicContact CD1-CB 4.12Å; L26-M48 HydrophobicContact CD1-CE 3.45Å; L26-M48 VanDerWaalsContact CD1-CE 3.45Å; L26-M48 HydrophobicContact CD1-SD 3.64Å
27R84.3Confident86.7Confident104 Ų10450.4 Ų50.439%0.39227%0.266SS..EExtended strand (participates in β ladder)trans-148.6137.6-169.4-178.7-177-73-151.93.1111.7C38 I39 L307 E314R27-C38 CarbonylContact O-C 3.57Å; R27-C38 VanDerWaalsContact O-CA 3.23Å; R27-C38 WeakPolarHBondContact O-CA 3.46Å; R27-I39 PolarHBondContact O-N 2.91Å; R27-L307 VanDerWaalsContact CD-CD1 3.4Å; R27-E314 VanDerWaalsContact CD-OE1 3.26Å; R27-E314 WeakPolarHBondContact CD-OE1 3.22Å; R27-E314 HydrophobicContact CG-CG 4.13Å; R27-E314 IonicContact CZ-OE1 3.58Å; R27-E314 IonicContact CZ-OE2 2.66Å; R27-E314 IonicContact NE-OE1 3.75Å; R27-E314 VanDerWaalsContact NH1-CD 3.26Å; R27-E314 IonicContact NH1-OE1 2.64Å; R27-E314 PolarHBondContact NH1-OE1 3.02Å; R27-E314 IonicContact NH1-OE2 3.77Å; R27-E314 PolarHBondContact NH1-OE2 2.93Å
28A85.2Confident87Confident2 Ų245.3 Ų45.32%0.01724%0.242CC..EExtended strand (participates in β ladder)trans-71.7134.8168.700000112.3E317A28-E317 HydrophobicContact CB-CB 4.48Å; A28-E317 WeakPolarHBondContact CB-OE2 3.27Å; A28-E317 PolarHBondContact N-OE2 3.09Å
29I83.8Confident87Confident32 Ų3245.1 Ų45.116%0.16424%0.241CC..EExtended strand (participates in β ladder)trans-125.9-6.9-177.857.1168.9000113.5V37 I39 A50 L102 L307 F313I29-V37 HydrophobicContact CD1-CG1 4.04Å; I29-V37 HydrophobicContact CG1-CB 4.26Å; I29-V37 HydrophobicContact CG1-CG1 3.91Å; I29-V37 WeakPolarHBondContact CG1-O 3.38Å; I29-V37 PolarHBondContact N-O 3.14Å; I29-I39 HydrophobicContact CD1-CG1 3.97Å; I29-I39 HydrophobicContact CG1-CG1 4.39Å; I29-I39 HydrophobicContact CG2-CD1 3.58Å; I29-I39 HydrophobicContact CG2-CG1 3.56Å; I29-A50 HydrophobicContact CD1-CB 4.29Å; I29-L102 HydrophobicContact CD1-CD1 4.1Å; I29-L307 HydrophobicContact CB-CD2 4.45Å; I29-L307 HydrophobicContact CG2-CD2 3.54Å; I29-F313 WeakPolarHBondContact O-CD2 3.35Å
30G82.9Confident87.1Confident14 Ų1443.2 Ų43.214%0.14423%0.23CC..EExtended strand (participates in β ladder)trans-168.3162.517800000112.4K36 V37G30-K36 WeakPolarHBondContact O-CA 3.41Å; G30-K36 WeakPolarHBondContact O-CB 3.44Å; G30-V37 PolarHBondContact N-O 2.66Å; G30-V37 PolarHBondContact O-N 2.85Å
31K81.9Confident87.3Confident117 Ų11742.8 Ų42.851%0.50923%0.229SC..EExtended strand (participates in β ladder)trans-124121.9178.5-171.9175.3-175.8168.10109.1F313 E316K31-F313 HydrophobicContact CB-CD1 3.92Å; K31-F313 HydrophobicContact CB-CE1 3.6Å; K31-E316 VanDerWaalsContact NZ-CD 3.32Å; K31-E316 IonicContact NZ-OE1 3.22Å; K31-E316 PolarHBondContact NZ-OE1 2.88Å; K31-E316 IonicContact NZ-OE2 2.7Å; K31-E316 PolarHBondContact NZ-OE2 3.45Å
32G75.1Confident87.5Confident36 Ų3640 Ų4037%0.37121%0.214SC..  trans-98.2171.8175.700000112F34 G35G32-F34 PolarHBondContact O-N 3.25Å; G32-G35 CarbonylContact C-O 3.59Å; G32-G35 PolarHBondContact N-O 3.34Å; G32-G35 VanDerWaalsContact O-O 3.04Å
33S74.8Confident87.5Confident88 Ų8841.3 Ų41.362%0.61522%0.219SC*.SBendtrans-59-28.4178.4-58.40000114R62S33-R62 PolarHBondContact O-NH1 2.82Å
34F80.4Confident87.5Confident31 Ų3145.9 Ų45.914%0.13624%0.244CC..SBendtrans-122.11.4-172.1-44.1-71.2000113.8G32 M54 N55 R62 E64G32-F34 PolarHBondContact O-N 3.25Å; F34-M54 HydrophobicContact CB-CB 4.4Å; F34-N55 PolarHBondContact O-N 2.75Å; F34-R62 HydrophobicContact CE1-CB 4.15Å; F34-R62 HydrophobicContact CE1-CG 4.5Å; F34-E64 HydrophobicContact CE1-CB 3.94Å; F34-E64 HydrophobicContact CE1-CG 3.68Å; F34-E64 HydrophobicContact CE2-CB 4.22Å; F34-E64 HydrophobicContact CE2-CG 4.3Å; F34-E64 HydrophobicContact CZ-CB 3.67Å; F34-E64 HydrophobicContact CZ-CG 3.37Å
35G83.8Confident87.6Confident19 Ų1945.6 Ų45.620%0.19625%0.247CC..EExtended strand (participates in β ladder)trans173.4-149.1-17700000112.1G32 Y53G32-G35 CarbonylContact C-O 3.59Å; G32-G35 PolarHBondContact N-O 3.34Å; G32-G35 VanDerWaalsContact O-O 3.04Å; G35-Y53 VanDerWaalsContact CA-O 3.31Å; G35-Y53 WeakPolarHBondContact CA-O 2.95Å
36K86.1Confident87.8Confident41 Ų4150.2 Ų50.218%0.17827%0.266CS..EExtended strand (participates in β ladder)trans-132.2168.6-179.1-33.7-175.8-169.5163.80111.4G30 Y53 E321G30-K36 WeakPolarHBondContact O-CA 3.41Å; G30-K36 WeakPolarHBondContact O-CB 3.44Å; K36-Y53 HydrophobicContact CB-CE1 3.98Å; K36-Y53 HydrophobicContact CB-CE2 3.83Å; K36-Y53 VanDerWaalsContact CB-CZ 3.4Å; K36-Y53 VanDerWaalsContact CB-OH 3.23Å; K36-Y53 WeakPolarHBondContact CB-OH 3.45Å; K36-Y53 WeakPolarHBondContact CD-OH 3.35Å; K36-Y53 HydrophobicContact CG-CE2 3.77Å; K36-Y53 VanDerWaalsContact CG-OH 3.25Å; K36-Y53 WeakPolarHBondContact CG-OH 3.47Å; K36-Y53 PolarHBondContact N-O 2.81Å; K36-Y53 VanDerWaalsContact O-CD1 3.32Å; K36-Y53 WeakPolarHBondContact O-CD1 3.33Å; K36-Y53 WeakPolarHBondContact O-CE1 3.46Å; K36-Y53 PolarHBondContact O-N 3.46Å; K36-E321 IonicContact NZ-OE1 3.58Å; K36-E321 PolarHBondContact NZ-OE1 2.71Å
37V90.4Very high88.2Confident38 Ų3850.7 Ų50.723%0.2327%0.265CS..EExtended strand (participates in β ladder)trans-113.8125.5173.4-173.30000107.8I29 G30 A50 M51 K52I29-V37 HydrophobicContact CD1-CG1 4.04Å; I29-V37 HydrophobicContact CG1-CB 4.26Å; I29-V37 HydrophobicContact CG1-CG1 3.91Å; I29-V37 WeakPolarHBondContact CG1-O 3.38Å; I29-V37 PolarHBondContact N-O 3.14Å; G30-V37 PolarHBondContact N-O 2.66Å; G30-V37 PolarHBondContact O-N 2.85Å; V37-A50 HydrophobicContact CG1-CB 4.2Å; V37-M51 CarbonylContact C-O 3.46Å; V37-M51 WeakPolarHBondContact CA-O 3.44Å; V37-K52 HydrophobicContact CG2-CB 4.24Å; V37-K52 HydrophobicContact CG2-CG 4.3Å
38C90.8Very high88.8Confident0 Ų049.1 Ų49.10%026%0.263CS..EExtended strand (participates in β ladder)trans-123.6147.2179.5-70.70000111.3I25 R27 V40 A50 M51 Y53I25-C38 HydrophobicContact CG2-CB 3.95Å; R27-C38 CarbonylContact O-C 3.57Å; R27-C38 VanDerWaalsContact O-CA 3.23Å; R27-C38 WeakPolarHBondContact O-CA 3.46Å; C38-V40 HydrophobicContact CB-CG1 4.48Å; C38-A50 CarbonylContact O-C 3.54Å; C38-A50 WeakPolarHBondContact O-CA 3.44Å; C38-M51 PolarHBondContact N-O 2.87Å; C38-M51 PolarHBondContact O-N 3.34Å; C38-Y53 HydrophobicContact CB-CE1 4.34Å
39I92Very high89.3Confident13 Ų1349.1 Ų49.17%0.06726%0.262CS..EExtended strand (participates in β ladder)trans-68.1131.5161.8-63.5175.3000108.2L26 R27 I29 M48 Y49 L102 L104 L307L26-I39 HydrophobicContact CB-CB 4.44Å; L26-I39 HydrophobicContact CB-CG2 4.27Å; L26-I39 HydrophobicContact CD1-CG2 4.05Å; L26-I39 PolarHBondContact N-O 3.31Å; R27-I39 PolarHBondContact O-N 2.91Å; I29-I39 HydrophobicContact CD1-CG1 3.97Å; I29-I39 HydrophobicContact CG1-CG1 4.39Å; I29-I39 HydrophobicContact CG2-CD1 3.58Å; I29-I39 HydrophobicContact CG2-CG1 3.56Å; I39-M48 HydrophobicContact CG2-CE 3.26Å; I39-M48 HydrophobicContact CG2-SD 4.5Å; I39-Y49 WeakPolarHBondContact CA-O 3.36Å; I39-L102 HydrophobicContact CD1-CD1 4.35Å; I39-L102 HydrophobicContact CG1-CD1 3.81Å; I39-L102 HydrophobicContact CG1-CD2 4.29Å; I39-L102 HydrophobicContact CG2-CD2 3.86Å; I39-L104 HydrophobicContact CD1-CD2 4.44Å; I39-L307 HydrophobicContact CD1-CD2 4.26Å
40V94.8Very high89.9Confident0 Ų048 Ų480%026%0.258CS..EExtended strand (participates in β ladder)trans-131.8150.3177.7-550000110.7F23 Q24 I25 C38 M48 Y49 M51F23-V40 HydrophobicContact CB-CB 4.3Å; F23-V40 HydrophobicContact CD1-CB 4.28Å; F23-V40 HydrophobicContact CD1-CG2 3.75Å; F23-V40 HydrophobicContact CE1-CG2 4.38Å; F23-V40 HydrophobicContact CG-CG2 4.44Å; Q24-V40 CarbonylContact O-C 3.57Å; Q24-V40 VanDerWaalsContact O-CA 3.28Å; Q24-V40 WeakPolarHBondContact O-CA 3.48Å; I25-V40 HydrophobicContact CD1-CB 4.33Å; I25-V40 HydrophobicContact CD1-CG1 3.34Å; C38-V40 HydrophobicContact CB-CG1 4.48Å; V40-M48 CarbonylContact O-C 3.58Å; V40-M48 WeakPolarHBondContact O-CA 3.46Å; V40-Y49 PolarHBondContact N-O 3.47Å; V40-Y49 PolarHBondContact O-N 2.69Å; V40-M51 HydrophobicContact CB-CB 4.33Å; V40-M51 HydrophobicContact CB-CE 4.33Å; V40-M51 HydrophobicContact CG1-CB 3.46Å; V40-M51 VanDerWaalsContact CG1-CB 3.46Å; V40-M51 HydrophobicContact CG1-CE 3.99Å; V40-M51 HydrophobicContact CG1-CG 4.37Å; V40-M51 HydrophobicContact CG1-SD 4.1Å; V40-M51 HydrophobicContact CG2-CB 3.88Å; V40-M51 HydrophobicContact CG2-CE 4.08Å
41Q95.9Very high90.5Very high45 Ų4547.3 Ų47.321%0.2125%0.251CS..EExtended strand (participates in β ladder)trans-115125.2172.3-170.5175.555.700109.9F23 Q24 L26 K43 K46 K47 M48F23-Q41 CarbonylContact C-O 3.56Å; F23-Q41 WeakPolarHBondContact CA-O 3.4Å; Q24-Q41 HydrophobicContact CB-CB 4.49Å; Q24-Q41 PolarHBondContact N-O 3.39Å; Q24-Q41 PolarHBondContact O-N 3.3Å; L26-Q41 HydrophobicContact CD1-CB 4.12Å; Q41-K43 PolarHBondContact O-N 3.11Å; Q41-K46 WeakPolarHBondContact CG-O 3.36Å; Q41-K46 PolarHBondContact NE2-O 2.68Å; Q41-K47 WeakPolarHBondContact CA-O 3.24Å; Q41-M48 HydrophobicContact CB-SD 3.61Å; Q41-M48 HydrophobicContact CG-SD 3.81Å
42K96.2Very high91Very high8 Ų843.8 Ų43.84%0.03524%0.236CC..EExtended strand (participates in β ladder)trans-70.8127.5172.2-160.3-172.4176.3-123.50109.2F23 D44 K46 K47 Y49 E367F23-K42 HydrophobicContact CD1-CB 4.04Å; F23-K42 HydrophobicContact CD1-CG 4.26Å; F23-K42 HydrophobicContact CE1-CB 3.82Å; F23-K42 HydrophobicContact CE1-CD 4.44Å; F23-K42 HydrophobicContact CE1-CG 3.84Å; F23-K42 HydrophobicContact CZ-CG 4.17Å; K42-D44 VanDerWaalsContact CD-OD1 3.24Å; K42-D44 WeakPolarHBondContact CD-OD1 3.3Å; K42-D44 WeakPolarHBondContact CE-OD1 3.49Å; K42-D44 WeakPolarHBondContact CG-OD1 3.19Å; K42-D44 VanDerWaalsContact NZ-CG 3.27Å; K42-D44 IonicContact NZ-OD1 3.04Å; K42-D44 PolarHBondContact NZ-OD1 3.37Å; K42-D44 IonicContact NZ-OD2 2.75Å; K42-D44 PolarHBondContact NZ-OD2 2.96Å; K42-D44 PolarHBondContact O-N 3.49Å; K42-K46 WeakPolarHBondContact O-CA 3.21Å; K42-K46 PolarHBondContact O-N 3.39Å; K42-K47 PolarHBondContact N-O 2.98Å; K42-Y49 HydrophobicContact CB-CD2 4.44Å; K42-Y49 HydrophobicContact CB-CE2 4.01Å; K42-E367 IonicContact NZ-OE2 2.68Å; K42-E367 PolarHBondContact NZ-OE2 2.77Å
43K94.8Very high91.7Very high95 Ų9543.4 Ų43.441%0.41322%0.223SC..THydrogen-bonded Turntrans-67.4-34.7-164.4-74.2177.6-178.1170.10114.3D21 H22 Q41 K46D21-K43 WeakPolarHBondContact O-CD 3.29Å; D21-K43 WeakPolarHBondContact O-CE 3.37Å; D21-K43 PolarHBondContact O-NZ 2.97Å; H22-K43 WeakPolarHBondContact O-CG 3.34Å; H22-K43 PolarHBondContact O-N 3.04Å; Q41-K43 PolarHBondContact O-N 3.11Å; K43-K46 WeakPolarHBondContact O-CD 3.45Å; K43-K46 VanDerWaalsContact O-CE 3.3Å; K43-K46 WeakPolarHBondContact O-CE 3.32Å; K43-K46 PolarHBondContact O-NZ 3.15Å
44D93.8Very high92.5Very high103 Ų10339.3 Ų39.355%0.55120%0.195SC*.THydrogen-bonded Turntrans-78.4-49.5-176.759.9-17.8000112.2K42K42-D44 VanDerWaalsContact CD-OD1 3.24Å; K42-D44 WeakPolarHBondContact CD-OD1 3.3Å; K42-D44 WeakPolarHBondContact CE-OD1 3.49Å; K42-D44 WeakPolarHBondContact CG-OD1 3.19Å; K42-D44 VanDerWaalsContact NZ-CG 3.27Å; K42-D44 IonicContact NZ-OD1 3.04Å; K42-D44 PolarHBondContact NZ-OD1 3.37Å; K42-D44 IonicContact NZ-OD2 2.75Å; K42-D44 PolarHBondContact NZ-OD2 2.96Å; K42-D44 PolarHBondContact O-N 3.49Å
45T94.8Very high93.1Very high70 Ų7039.5 Ų39.543%0.42920%0.197SC..THydrogen-bonded Turntrans-90.1-14.8-175.957.50000113.4K47T45-K47 PolarHBondContact O-N 2.73Å; T45-K47 VanDerWaalsContact O-N 3.08Å; T45-K47 PolarHBondContact OG1-N 2.74Å
46K95.1Very high93.6Very high123 Ų12338.9 Ų38.954%0.53519%0.189SC..  trans59.610.2-170.2-52.8-54.6-174.9-165.80114.5Q41 K42 K43Q41-K46 WeakPolarHBondContact CG-O 3.36Å; Q41-K46 PolarHBondContact NE2-O 2.68Å; K42-K46 WeakPolarHBondContact O-CA 3.21Å; K42-K46 PolarHBondContact O-N 3.39Å; K43-K46 WeakPolarHBondContact O-CD 3.45Å; K43-K46 VanDerWaalsContact O-CE 3.3Å; K43-K46 WeakPolarHBondContact O-CE 3.32Å; K43-K46 PolarHBondContact O-NZ 3.15Å
47K95.6Very high93.8Very high86 Ų8640.1 Ų40.137%0.37420%0.197SC..  trans-71139.7177.9-174.2165.5166.1-172.90110.7Q41 K42 T45 Y49 W87Q41-K47 WeakPolarHBondContact CA-O 3.24Å; K42-K47 PolarHBondContact N-O 2.98Å; T45-K47 PolarHBondContact O-N 2.73Å; T45-K47 VanDerWaalsContact O-N 3.08Å; T45-K47 PolarHBondContact OG1-N 2.74Å; K47-Y49 HydrophobicContact CB-CE2 3.78Å; K47-Y49 HydrophobicContact CD-CE1 4.32Å; K47-Y49 HydrophobicContact CD-CE2 4.22Å; K47-Y49 VanDerWaalsContact CD-OH 3.26Å; K47-Y49 WeakPolarHBondContact CD-OH 3.37Å; K47-Y49 HydrophobicContact CG-CD2 4.45Å; K47-Y49 HydrophobicContact CG-CE1 4.4Å; K47-Y49 HydrophobicContact CG-CE2 3.68Å; K47-Y49 WeakPolarHBondContact O-CD2 3.18Å; K47-W87 VanDerWaalsContact NZ-CH2 3.35Å; K47-W87 VanDerWaalsContact NZ-CZ2 3.28Å
48M95.9Very high93.9Very high71 Ų7143 Ų4335%0.3521%0.207SC..EExtended strand (participates in β ladder)trans-96.4142-176.1-63.4-76.6-74.700110.4L26 I39 V40 Q41 L102L26-M48 HydrophobicContact CD1-CE 3.45Å; L26-M48 VanDerWaalsContact CD1-CE 3.45Å; L26-M48 HydrophobicContact CD1-SD 3.64Å; I39-M48 HydrophobicContact CG2-CE 3.26Å; I39-M48 HydrophobicContact CG2-SD 4.5Å; V40-M48 CarbonylContact O-C 3.58Å; V40-M48 WeakPolarHBondContact O-CA 3.46Å; Q41-M48 HydrophobicContact CB-SD 3.61Å; Q41-M48 HydrophobicContact CG-SD 3.81Å; M48-L102 HydrophobicContact CB-CD2 3.81Å; M48-L102 HydrophobicContact CE-CD2 4.29Å
49Y97.1Very high94Very high1 Ų143 Ų430%0.00421%0.207CC..EExtended strand (participates in β ladder)trans-142.9165.6-178.5-60.9-88.7000110.6F23 I39 V40 K42 K47 W87 Y88 V99 V100F23-Y49 HydrophobicContact CE1-CD2 4.18Å; I39-Y49 WeakPolarHBondContact CA-O 3.36Å; V40-Y49 PolarHBondContact N-O 3.47Å; V40-Y49 PolarHBondContact O-N 2.69Å; K42-Y49 HydrophobicContact CB-CD2 4.44Å; K42-Y49 HydrophobicContact CB-CE2 4.01Å; K47-Y49 HydrophobicContact CB-CE2 3.78Å; K47-Y49 HydrophobicContact CD-CE1 4.32Å; K47-Y49 HydrophobicContact CD-CE2 4.22Å; K47-Y49 VanDerWaalsContact CD-OH 3.26Å; K47-Y49 WeakPolarHBondContact CD-OH 3.37Å; K47-Y49 HydrophobicContact CG-CD2 4.45Å; K47-Y49 HydrophobicContact CG-CE1 4.4Å; K47-Y49 HydrophobicContact CG-CE2 3.68Å; K47-Y49 WeakPolarHBondContact O-CD2 3.18Å; Y49-W87 HydrophobicContact CD1-CB 4.47Å; Y49-W87 AromaticContact CD1-CD1 3.98Å; Y49-W87 HydrophobicContact CD1-CG 4.15Å; Y49-W87 HydrophobicContact CE1-CB 4.06Å; Y49-W87 AromaticContact CE1-CD1 3.73Å; Y49-W87 AromaticContact CE1-CD2 3.81Å; Y49-W87 HydrophobicContact CE1-CD2 3.81Å; Y49-W87 HydrophobicContact CE1-CE3 4.44Å; Y49-W87 AromaticContact CE1-CG 3.59Å; Y49-W87 HydrophobicContact CE1-CG 3.59Å; Y49-Y88 HydrophobicContact CE1-CE2 4.07Å; Y49-Y88 HydrophobicContact CE2-CE2 4.21Å; Y49-Y88 AromaticContact CZ-CE2 3.81Å; Y49-Y88 PolarHBondContact OH-OH 2.85Å; Y49-V99 VanDerWaalsContact CB-CG1 3.43Å; Y49-V99 HydrophobicContact CD1-CG1 3.91Å; Y49-V99 HydrophobicContact CD2-CG1 4.31Å; Y49-V99 HydrophobicContact CG-CG1 3.64Å; Y49-V100 WeakPolarHBondContact CB-O 3.47Å
50A95.9Very high94Very high9 Ų942.4 Ų42.47%0.07420%0.204CC..EExtended strand (participates in β ladder)trans-97.4131.316200000109I29 V37 C38 V99 V100 L102I29-A50 HydrophobicContact CD1-CB 4.29Å; V37-A50 HydrophobicContact CG1-CB 4.2Å; C38-A50 CarbonylContact O-C 3.54Å; C38-A50 WeakPolarHBondContact O-CA 3.44Å; A50-V99 WeakPolarHBondContact O-CA 3.42Å; A50-V100 HydrophobicContact CB-CG2 3.95Å; A50-V100 PolarHBondContact N-O 2.87Å; A50-V100 PolarHBondContact O-N 3.07Å; A50-L102 HydrophobicContact CB-CD1 4.19Å
51M95.5Very high93.9Very high0 Ų048.4 Ų48.40%023%0.232CC..EExtended strand (participates in β ladder)trans-115.8117.5176.8-176.9-175.6-69.800109.9F20 F23 I25 V37 C38 V40 F90 F97 M98 V99F20-M51 HydrophobicContact CD2-SD 4.14Å; F20-M51 HydrophobicContact CE2-SD 4.06Å; F23-M51 HydrophobicContact CB-CE 3.75Å; F23-M51 HydrophobicContact CD1-CE 4.1Å; F23-M51 HydrophobicContact CD2-CE 3.71Å; F23-M51 HydrophobicContact CE2-CE 4.35Å; F23-M51 HydrophobicContact CG-CE 3.57Å; I25-M51 HydrophobicContact CD1-CE 4.42Å; I25-M51 HydrophobicContact CD1-SD 3.98Å; V37-M51 CarbonylContact C-O 3.46Å; V37-M51 WeakPolarHBondContact CA-O 3.44Å; C38-M51 PolarHBondContact N-O 2.87Å; C38-M51 PolarHBondContact O-N 3.34Å; V40-M51 HydrophobicContact CB-CB 4.33Å; V40-M51 HydrophobicContact CB-CE 4.33Å; V40-M51 HydrophobicContact CG1-CB 3.46Å; V40-M51 VanDerWaalsContact CG1-CB 3.46Å; V40-M51 HydrophobicContact CG1-CE 3.99Å; V40-M51 HydrophobicContact CG1-CG 4.37Å; V40-M51 HydrophobicContact CG1-SD 4.1Å; V40-M51 HydrophobicContact CG2-CB 3.88Å; V40-M51 HydrophobicContact CG2-CE 4.08Å; M51-F90 HydrophobicContact CE-CE2 4.5Å; M51-F90 HydrophobicContact CE-CZ 3.69Å; M51-F90 HydrophobicContact SD-CZ 4.49Å; M51-F97 HydrophobicContact CG-CD1 4.28Å; M51-F97 HydrophobicContact SD-CD1 3.7Å; M51-F97 HydrophobicContact SD-CE1 4.39Å; M51-F97 HydrophobicContact SD-CG 4.5Å; M51-M98 CarbonylContact C-O 3.56Å; M51-M98 VanDerWaalsContact CA-O 3.29Å; M51-M98 WeakPolarHBondContact CA-O 3.35Å; M51-V99 HydrophobicContact CB-CG2 4.4Å; M51-V99 HydrophobicContact CE-CG2 3.77Å; M51-V99 HydrophobicContact CG-CG2 4.1Å
52K93Very high93.6Very high42 Ų4253.3 Ų53.318%0.18325%0.248CC..EExtended strand (participates in β ladder)trans-91.5121.1169.3-179.2-174.9179.9-170.10107.6V37 M54 E71 F97 M98 N166V37-K52 HydrophobicContact CG2-CB 4.24Å; V37-K52 HydrophobicContact CG2-CG 4.3Å; K52-M54 HydrophobicContact CD-SD 4.22Å; K52-M54 HydrophobicContact CG-CG 4.19Å; K52-M54 HydrophobicContact CG-SD 4.39Å; K52-E71 IonicContact NZ-OE1 3.65Å; K52-E71 PolarHBondContact NZ-OE1 3.14Å; K52-E71 IonicContact NZ-OE2 3.7Å; K52-E71 PolarHBondContact NZ-OE2 3.24Å; K52-F97 WeakPolarHBondContact O-CA 3.37Å; K52-M98 HydrophobicContact CB-CB 4.31Å; K52-M98 HydrophobicContact CD-SD 4.39Å; K52-M98 PolarHBondContact N-O 3.15Å; K52-M98 PolarHBondContact O-N 2.93Å; K52-N166 PolarHBondContact NZ-OD1 3.29Å
53Y89.6Confident93.3Very high28 Ų2857.7 Ų57.711%0.1127%0.272CS..EExtended strand (participates in β ladder)trans-108.5139.4170.549.9-89.5000110.1G35 K36 C38 M96G35-Y53 VanDerWaalsContact CA-O 3.31Å; G35-Y53 WeakPolarHBondContact CA-O 2.95Å; K36-Y53 HydrophobicContact CB-CE1 3.98Å; K36-Y53 HydrophobicContact CB-CE2 3.83Å; K36-Y53 VanDerWaalsContact CB-CZ 3.4Å; K36-Y53 VanDerWaalsContact CB-OH 3.23Å; K36-Y53 WeakPolarHBondContact CB-OH 3.45Å; K36-Y53 WeakPolarHBondContact CD-OH 3.35Å; K36-Y53 HydrophobicContact CG-CE2 3.77Å; K36-Y53 VanDerWaalsContact CG-OH 3.25Å; K36-Y53 WeakPolarHBondContact CG-OH 3.47Å; K36-Y53 PolarHBondContact N-O 2.81Å; K36-Y53 VanDerWaalsContact O-CD1 3.32Å; K36-Y53 WeakPolarHBondContact O-CD1 3.33Å; K36-Y53 WeakPolarHBondContact O-CE1 3.46Å; K36-Y53 PolarHBondContact O-N 3.46Å; C38-Y53 HydrophobicContact CB-CE1 4.34Å; Y53-M96 CarbonylContact C-O 3.6Å; Y53-M96 WeakPolarHBondContact CA-O 3.49Å
54M92.3Very high93.2Very high3 Ų356 Ų562%0.01527%0.265CS..EExtended strand (participates in β ladder)trans-131.1119.2-172.8-63.8162.3-73.900108.7F34 K52 K56 V68 D95 M96 M98F34-M54 HydrophobicContact CB-CB 4.4Å; K52-M54 HydrophobicContact CD-SD 4.22Å; K52-M54 HydrophobicContact CG-CG 4.19Å; K52-M54 HydrophobicContact CG-SD 4.39Å; M54-K56 PolarHBondContact O-N 2.99Å; M54-V68 HydrophobicContact CE-CG1 3.91Å; M54-V68 HydrophobicContact SD-CG1 3.76Å; M54-V68 HydrophobicContact SD-CG2 3.97Å; M54-D95 WeakPolarHBondContact O-CA 3.08Å; M54-M96 HydrophobicContact CB-CB 4.48Å; M54-M96 HydrophobicContact CB-CE 4.36Å; M54-M96 HydrophobicContact CE-CB 4.19Å; M54-M96 PolarHBondContact N-O 3.31Å; M54-M96 PolarHBondContact O-N 3.16Å; M54-M98 HydrophobicContact CE-CB 4.35Å; M54-M98 HydrophobicContact CE-CG 3.63Å; M54-M98 HydrophobicContact CE-SD 3.5Å; M54-M98 VanDerWaalsContact CE-SD 3.5Å; M54-M98 HydrophobicContact SD-SD 4.2Å
55N93Very high93.1Very high35 Ų3552.1 Ų52.119%0.18725%0.245CC..EExtended strand (participates in β ladder)trans-71.5122.5-176.5-176-99.4000111.8F34 L57 K58 C59 E94 D95F34-N55 PolarHBondContact O-N 2.75Å; N55-L57 VanDerWaalsContact C-N 3.35Å; N55-L57 PolarHBondContact O-N 3.46Å; N55-L57 WeakPolarHBondContact OD1-CB 3.44Å; N55-L57 PolarHBondContact OD1-N 2.96Å; N55-K58 HydrophobicContact CB-CB 4.2Å; N55-K58 HydrophobicContact CB-CD 4.11Å; N55-K58 HydrophobicContact CB-CG 4.2Å; N55-K58 PolarHBondContact O-N 3.22Å; N55-K58 PolarHBondContact OD1-N 2.82Å; N55-K58 VanDerWaalsContact OD1-N 3.11Å; N55-C59 PolarHBondContact O-N 3.01Å; N55-C59 PolarHBondContact O-SG 3.25Å; N55-C59 VanDerWaalsContact O-SG 3.33Å; N55-E94 PolarHBondContact ND2-O 2.81Å; N55-D95 WeakPolarHBondContact CA-OD1 3.49Å; N55-D95 WeakPolarHBondContact CB-OD1 3.47Å; N55-D95 PolarHBondContact ND2-OD1 2.77Å; N55-D95 VanDerWaalsContact ND2-OD1 3.14Å
56K92.4Very high92.9Very high5 Ų558.1 Ų58.12%0.02226%0.26CS..Hα-helixtrans-58.7-46.2-174.8-71.5178.8169.4-173.70111.9M54 K58 C59 V60 D92 E94 M96 L354 V357M54-K56 PolarHBondContact O-N 2.99Å; K56-K58 PolarHBondContact O-N 3.35Å; K56-C59 PolarHBondContact O-N 3.3Å; K56-V60 WeakPolarHBondContact O-CG2 3.46Å; K56-V60 PolarHBondContact O-N 3.08Å; K56-D92 VanDerWaalsContact CE-O 3.25Å; K56-D92 WeakPolarHBondContact CE-O 3.4Å; K56-D92 PolarHBondContact NZ-O 2.89Å; K56-E94 WeakPolarHBondContact CB-O 3.23Å; K56-E94 WeakPolarHBondContact CG-O 3.42Å; K56-E94 PolarHBondContact N-O 3.25Å; K56-M96 HydrophobicContact CG-CG 3.94Å; K56-L354 HydrophobicContact CB-CD2 3.74Å; K56-V357 HydrophobicContact CD-CG1 4.4Å; K56-V357 HydrophobicContact CG-CG1 4.31Å
57L91.3Very high92.6Very high67 Ų6755.6 Ų55.635%0.35125%0.253SS..Hα-helixtrans-59.2-50.3179.5178.460.3000111.1N55 C59 V60 E61 L350N55-L57 VanDerWaalsContact C-N 3.35Å; N55-L57 PolarHBondContact O-N 3.46Å; N55-L57 WeakPolarHBondContact OD1-CB 3.44Å; N55-L57 PolarHBondContact OD1-N 2.96Å; L57-C59 VanDerWaalsContact C-N 3.31Å; L57-C59 PolarHBondContact O-N 2.79Å; L57-V60 PolarHBondContact O-N 2.83Å; L57-V60 VanDerWaalsContact O-N 3.15Å; L57-E61 HydrophobicContact CD1-CG 4.14Å; L57-E61 HydrophobicContact CG-CG 4.47Å; L57-E61 WeakPolarHBondContact O-CG 3.28Å; L57-E61 PolarHBondContact O-N 2.7Å; L57-L350 HydrophobicContact CD1-CD1 3.81Å; L57-L350 HydrophobicContact CD1-CD2 3.72Å; L57-L350 HydrophobicContact CD1-CG 4.14Å
58K92.3Very high92.4Very high99 Ų9951.7 Ų51.743%0.4324%0.236SC..Hα-helixtrans-60.3-39.1177.1-69.3-178.6-176.5174.90112.9N55 K56 R62N55-K58 HydrophobicContact CB-CB 4.2Å; N55-K58 HydrophobicContact CB-CD 4.11Å; N55-K58 HydrophobicContact CB-CG 4.2Å; N55-K58 PolarHBondContact O-N 3.22Å; N55-K58 PolarHBondContact OD1-N 2.82Å; N55-K58 VanDerWaalsContact OD1-N 3.11Å; K56-K58 PolarHBondContact O-N 3.35Å; K58-R62 WeakPolarHBondContact O-CB 3.36Å; K58-R62 WeakPolarHBondContact O-CG 3.26Å; K58-R62 PolarHBondContact O-N 3.33Å; K58-R62 VanDerWaalsContact O-N 3.13Å
59C92.3Very high92.3Very high0 Ų049.7 Ų49.70%023%0.227CC..Hα-helixtrans-65.7-40.1176.5-70.70000111.8N55 K56 L57 N63 E64 V65 M96N55-C59 PolarHBondContact O-N 3.01Å; N55-C59 PolarHBondContact O-SG 3.25Å; N55-C59 VanDerWaalsContact O-SG 3.33Å; K56-C59 PolarHBondContact O-N 3.3Å; L57-C59 VanDerWaalsContact C-N 3.31Å; L57-C59 PolarHBondContact O-N 2.79Å; C59-N63 PolarHBondContact O-N 3.06Å; C59-N63 VanDerWaalsContact O-N 3.09Å; C59-E64 PolarHBondContact O-N 3.09Å; C59-V65 HydrophobicContact CB-CG2 3.95Å; C59-M96 HydrophobicContact CB-CE 4.11Å
60V92.7Very high92Very high1 Ų153.1 Ų53.11%0.00624%0.241CC..Hα-helixtrans-67.6-47177.9170.30000111.2K56 L57 R62 N63 V65 L350 R353 L354 V357K56-V60 WeakPolarHBondContact O-CG2 3.46Å; K56-V60 PolarHBondContact O-N 3.08Å; L57-V60 PolarHBondContact O-N 2.83Å; L57-V60 VanDerWaalsContact O-N 3.15Å; V60-R62 VanDerWaalsContact C-N 3.28Å; V60-R62 PolarHBondContact O-N 3.46Å; V60-N63 PolarHBondContact O-N 3.4Å; V60-N63 VanDerWaalsContact O-N 3.13Å; V60-V65 HydrophobicContact CG2-CG2 3.72Å; V60-L350 HydrophobicContact CG1-CD1 3.75Å; V60-R353 HydrophobicContact CG1-CB 3.69Å; V60-R353 HydrophobicContact CG1-CG 4.44Å; V60-R353 HydrophobicContact CG2-CB 4.46Å; V60-R353 PolarHBondContact O-NH1 3.17Å; V60-R353 PolarHBondContact O-NH2 2.86Å; V60-L354 HydrophobicContact CG2-CD2 4Å; V60-V357 HydrophobicContact CG2-CG2 3.8Å
61E91.8Very high91.9Very high126 Ų12653 Ų5359%0.58924%0.239SC*.Hα-helixtrans-59.5-38.6178.7-73.3174.9160.800112.2L57L57-E61 HydrophobicContact CD1-CG 4.14Å; L57-E61 HydrophobicContact CG-CG 4.47Å; L57-E61 WeakPolarHBondContact O-CG 3.28Å; L57-E61 PolarHBondContact O-N 2.7Å
62R90.4Very high91.8Very high148 Ų14853.1 Ų53.156%0.55824%0.24SC*.THydrogen-bonded Turntrans-89.30.1179.1-65.5178.7176.9-176.53.7114.2S33 F34 K58 V60 E64S33-R62 PolarHBondContact O-NH1 2.82Å; F34-R62 HydrophobicContact CE1-CB 4.15Å; F34-R62 HydrophobicContact CE1-CG 4.5Å; K58-R62 WeakPolarHBondContact O-CB 3.36Å; K58-R62 WeakPolarHBondContact O-CG 3.26Å; K58-R62 PolarHBondContact O-N 3.33Å; K58-R62 VanDerWaalsContact O-N 3.13Å; V60-R62 VanDerWaalsContact C-N 3.28Å; V60-R62 PolarHBondContact O-N 3.46Å; R62-E64 VanDerWaalsContact C-N 3.34Å; R62-E64 HydrophobicContact CB-CG 3.91Å; R62-E64 PolarHBondContact O-N 3.2Å
63N90.8Very high91.8Very high99 Ų9955.8 Ų55.853%0.52925%0.253SS..THydrogen-bonded Turntrans60.737.1-178.5-161.243000114.6C59 V60 R353C59-N63 PolarHBondContact O-N 3.06Å; C59-N63 VanDerWaalsContact O-N 3.09Å; V60-N63 PolarHBondContact O-N 3.4Å; V60-N63 VanDerWaalsContact O-N 3.13Å; N63-R353 PolarHBondContact OD1-NH2 2.96Å
64E91.3Very high92Very high59 Ų5954.6 Ų54.628%0.27625%0.249SC..  trans-105-6.9-171.5-72.1-75.4164.900113.4F34 C59 R62 R66 N67 V68F34-E64 HydrophobicContact CE1-CB 3.94Å; F34-E64 HydrophobicContact CE1-CG 3.68Å; F34-E64 HydrophobicContact CE2-CB 4.22Å; F34-E64 HydrophobicContact CE2-CG 4.3Å; F34-E64 HydrophobicContact CZ-CB 3.67Å; F34-E64 HydrophobicContact CZ-CG 3.37Å; C59-E64 PolarHBondContact O-N 3.09Å; R62-E64 VanDerWaalsContact C-N 3.34Å; R62-E64 HydrophobicContact CB-CG 3.91Å; R62-E64 PolarHBondContact O-N 3.2Å; E64-R66 PolarHBondContact O-N 2.66Å; E64-N67 WeakPolarHBondContact O-CB 3.24Å; E64-N67 PolarHBondContact O-N 2.99Å; E64-N67 PolarHBondContact OE2-ND2 2.95Å; E64-V68 PolarHBondContact O-N 3.31Å; E64-V68 VanDerWaalsContact O-N 3.07Å
65V91.7Very high92.2Very high22 Ų2254.8 Ų54.813%0.13325%0.25CC..Hα-helixtrans-51.9-43.7179177.30000111.7C59 V60 N67 V68 L69 V357C59-V65 HydrophobicContact CB-CG2 3.95Å; V60-V65 HydrophobicContact CG2-CG2 3.72Å; V65-N67 VanDerWaalsContact C-N 3.29Å; V65-N67 PolarHBondContact O-N 3.18Å; V65-V68 PolarHBondContact O-N 2.56Å; V65-L69 HydrophobicContact CG1-CD1 3.99Å; V65-L69 HydrophobicContact CG1-CG 4.25Å; V65-L69 WeakPolarHBondContact O-CG 3.44Å; V65-L69 PolarHBondContact O-N 3.21Å; V65-V357 HydrophobicContact CB-CG2 4.45Å; V65-V357 HydrophobicContact CG1-CG1 4.39Å; V65-V357 HydrophobicContact CG1-CG2 3.77Å; V65-V357 HydrophobicContact CG2-CG2 3.79Å
66R90.7Very high92.3Very high197 Ų19755.4 Ų55.474%0.74325%0.251SS*.Hα-helixtrans-62-37.2179.3-70.9-177.2178.9164.6-0.1112.5E64 K70E64-R66 PolarHBondContact O-N 2.66Å; R66-K70 VanDerWaalsContact O-CB 3.27Å; R66-K70 WeakPolarHBondContact O-CB 3.37Å; R66-K70 PolarHBondContact O-N 3.34Å
67N90Very high92.3Very high69 Ų6960 Ų6037%0.36928%0.276SS..Hα-helixtrans-69.9-41.7178.4-65.5-25.7000110.6E64 V65 K70 E71E64-N67 WeakPolarHBondContact O-CB 3.24Å; E64-N67 PolarHBondContact O-N 2.99Å; E64-N67 PolarHBondContact OE2-ND2 2.95Å; V65-N67 VanDerWaalsContact C-N 3.29Å; V65-N67 PolarHBondContact O-N 3.18Å; N67-K70 PolarHBondContact O-N 2.94Å; N67-E71 WeakPolarHBondContact O-CB 3.46Å; N67-E71 PolarHBondContact O-N 3.49Å
68V91.3Very high92.6Very high4 Ų457.1 Ų57.12%0.02426%0.261CS..Hα-helixtrans-61.5-47.8175.1176.20000111.6M54 E64 V65 K70 E71 L72 M96M54-V68 HydrophobicContact CE-CG1 3.91Å; M54-V68 HydrophobicContact SD-CG1 3.76Å; M54-V68 HydrophobicContact SD-CG2 3.97Å; E64-V68 PolarHBondContact O-N 3.31Å; E64-V68 VanDerWaalsContact O-N 3.07Å; V65-V68 PolarHBondContact O-N 2.56Å; V68-K70 VanDerWaalsContact C-N 3.3Å; V68-K70 PolarHBondContact O-N 3.32Å; V68-E71 WeakPolarHBondContact O-CB 3.45Å; V68-E71 PolarHBondContact O-N 3.11Å; V68-L72 HydrophobicContact CG1-CD1 4.34Å; V68-L72 WeakPolarHBondContact O-CG 3.44Å; V68-L72 PolarHBondContact O-N 2.87Å; V68-M96 HydrophobicContact CB-CE 4.49Å; V68-M96 HydrophobicContact CG1-CE 4.03Å; V68-M96 HydrophobicContact CG1-SD 4.21Å
69L92.3Very high92.9Very high30 Ų3056.3 Ų56.316%0.15726%0.259CS..Hα-helixtrans-63.6-37.1178.1-66.4179.1000112V65 L72 Q73 D360 F361V65-L69 HydrophobicContact CG1-CD1 3.99Å; V65-L69 HydrophobicContact CG1-CG 4.25Å; V65-L69 WeakPolarHBondContact O-CG 3.44Å; V65-L69 PolarHBondContact O-N 3.21Å; L69-L72 HydrophobicContact CD2-CD1 4.36Å; L69-Q73 WeakPolarHBondContact O-CB 3.23Å; L69-Q73 PolarHBondContact O-N 2.86Å; L69-D360 HydrophobicContact CD1-CB 4.18Å; L69-F361 HydrophobicContact CD2-CD2 4.09Å
70K92.2Very high93.2Very high72 Ų7257.3 Ų57.331%0.31326%0.264SS..Hα-helixtrans-66-43174.3-174.5-172.4-180-1610112R66 N67 V68 Q73 I74 A168R66-K70 VanDerWaalsContact O-CB 3.27Å; R66-K70 WeakPolarHBondContact O-CB 3.37Å; R66-K70 PolarHBondContact O-N 3.34Å; N67-K70 PolarHBondContact O-N 2.94Å; V68-K70 VanDerWaalsContact C-N 3.3Å; V68-K70 PolarHBondContact O-N 3.32Å; K70-Q73 PolarHBondContact O-N 2.85Å; K70-I74 HydrophobicContact CG-CD1 4.19Å; K70-I74 WeakPolarHBondContact O-CG1 3.45Å; K70-I74 PolarHBondContact O-N 3.06Å; K70-A168 WeakPolarHBondContact CE-O 3.23Å; K70-A168 PolarHBondContact NZ-O 3.48Å
71E93Very high93.4Very high6 Ų659.8 Ų59.83%0.02828%0.28CS..Hα-helixtrans-57.1-50.8174.9-174.7-172.9-162.500110.1K52 N67 V68 Q73 I74 M75 M98 F165 N166K52-E71 IonicContact NZ-OE1 3.65Å; K52-E71 PolarHBondContact NZ-OE1 3.14Å; K52-E71 IonicContact NZ-OE2 3.7Å; K52-E71 PolarHBondContact NZ-OE2 3.24Å; N67-E71 WeakPolarHBondContact O-CB 3.46Å; N67-E71 PolarHBondContact O-N 3.49Å; V68-E71 WeakPolarHBondContact O-CB 3.45Å; V68-E71 PolarHBondContact O-N 3.11Å; E71-Q73 VanDerWaalsContact C-N 3.33Å; E71-Q73 PolarHBondContact O-N 3.1Å; E71-I74 PolarHBondContact O-N 2.97Å; E71-M75 HydrophobicContact CG-CG 4.35Å; E71-M75 HydrophobicContact CG-SD 3.9Å; E71-M75 WeakPolarHBondContact O-CB 3.22Å; E71-M75 WeakPolarHBondContact O-CG 3.42Å; E71-M75 PolarHBondContact O-N 2.79Å; E71-M98 HydrophobicContact CG-CE 4.03Å; E71-F165 HydrophobicContact CG-CB 4.23Å; E71-N166 PolarHBondContact OE1-OD1 3.2Å; E71-N166 PolarHBondContact OE2-OD1 3.29Å
72L92.7Very high93.8Very high3 Ų353.8 Ų53.82%0.01625%0.252CS..Hα-helixtrans-55-46.8174.8-76.2169.5000112.2V68 L69 I74 M75 Q76 F86 M98 F361V68-L72 HydrophobicContact CG1-CD1 4.34Å; V68-L72 WeakPolarHBondContact O-CG 3.44Å; V68-L72 PolarHBondContact O-N 2.87Å; L69-L72 HydrophobicContact CD2-CD1 4.36Å; L72-I74 VanDerWaalsContact C-N 3.3Å; L72-I74 PolarHBondContact O-N 2.79Å; L72-M75 PolarHBondContact O-N 2.64Å; L72-Q76 WeakPolarHBondContact O-CG 3.42Å; L72-Q76 PolarHBondContact O-N 2.81Å; L72-F86 HydrophobicContact CD2-CE1 4.21Å; L72-F86 HydrophobicContact CD2-CE2 3.9Å; L72-F86 HydrophobicContact CD2-CZ 3.47Å; L72-F86 VanDerWaalsContact CD2-CZ 3.47Å; L72-M98 HydrophobicContact CD2-CE 4.06Å; L72-M98 HydrophobicContact CD2-CG 3.54Å; L72-M98 HydrophobicContact CD2-SD 3.97Å; L72-M98 HydrophobicContact CG-CG 4.35Å; L72-M98 HydrophobicContact CG-SD 4.26Å; L72-F361 HydrophobicContact CD1-CD2 4.11Å; L72-F361 HydrophobicContact CD1-CE2 3.49Å; L72-F361 VanDerWaalsContact CD1-CE2 3.49Å; L72-F361 HydrophobicContact CD1-CZ 3.9Å
73Q93.4Very high94.1Very high98 Ų9846.8 Ų46.846%0.45823%0.225SC..Hα-helixtrans-62.6-37.3-179.5-175.6-172.9-15.400112.6L69 K70 E71 Q76 N77L69-Q73 WeakPolarHBondContact O-CB 3.23Å; L69-Q73 PolarHBondContact O-N 2.86Å; K70-Q73 PolarHBondContact O-N 2.85Å; E71-Q73 VanDerWaalsContact C-N 3.33Å; E71-Q73 PolarHBondContact O-N 3.1Å; Q73-Q76 VanDerWaalsContact O-CG 3.28Å; Q73-Q76 WeakPolarHBondContact O-CG 3.35Å; Q73-N77 PolarHBondContact O-ND2 3.02Å
74I95.1Very high94.5Very high3 Ų342.3 Ų42.32%0.01520%0.201CC..Hα-helixtrans-68.6-55.3175.2-73172000109.2K70 E71 L72 Q76 N77 L78 I142 F165 A168 I170K70-I74 HydrophobicContact CG-CD1 4.19Å; K70-I74 WeakPolarHBondContact O-CG1 3.45Å; K70-I74 PolarHBondContact O-N 3.06Å; E71-I74 PolarHBondContact O-N 2.97Å; L72-I74 VanDerWaalsContact C-N 3.3Å; L72-I74 PolarHBondContact O-N 2.79Å; I74-Q76 PolarHBondContact O-N 3.31Å; I74-N77 PolarHBondContact O-N 3.2Å; I74-N77 VanDerWaalsContact O-N 3.09Å; I74-L78 HydrophobicContact CG2-CD1 3.8Å; I74-L78 HydrophobicContact CG2-CG 4.44Å; I74-L78 WeakPolarHBondContact O-CG 3.38Å; I74-I142 HydrophobicContact CG2-CD1 3.81Å; I74-I142 HydrophobicContact CG2-CG1 4.37Å; I74-I142 HydrophobicContact CG2-CG2 4.45Å; I74-F165 HydrophobicContact CG2-CB 4.48Å; I74-F165 HydrophobicContact CG2-CD1 4.03Å; I74-F165 HydrophobicContact CG2-CG 4.47Å; I74-A168 HydrophobicContact CD1-CB 3.84Å; I74-I170 HydrophobicContact CD1-CG1 4.27Å; I74-I170 HydrophobicContact CG1-CD1 4.08Å; I74-I170 HydrophobicContact CG1-CG1 4.09Å
75M95.1Very high94.8Very high8 Ų840.5 Ų40.54%0.03919%0.194CC..Hα-helixtrans-65-32.1-170.1-68.9-17384.200114.3E71 L72 N77 L78 F86 M98 V100 F165E71-M75 HydrophobicContact CG-CG 4.35Å; E71-M75 HydrophobicContact CG-SD 3.9Å; E71-M75 WeakPolarHBondContact O-CB 3.22Å; E71-M75 WeakPolarHBondContact O-CG 3.42Å; E71-M75 PolarHBondContact O-N 2.79Å; L72-M75 PolarHBondContact O-N 2.64Å; M75-N77 PolarHBondContact O-N 3.26Å; M75-L78 PolarHBondContact O-N 2.87Å; M75-F86 HydrophobicContact CB-CB 3.81Å; M75-F86 HydrophobicContact CB-CD1 4.19Å; M75-F86 HydrophobicContact CB-CG 4.02Å; M75-F86 HydrophobicContact CE-CB 4.09Å; M75-M98 HydrophobicContact SD-CE 3.4Å; M75-M98 WeakPolarHBondContact SD-CE 3.29Å; M75-V100 HydrophobicContact CE-CG1 4.01Å; M75-F165 HydrophobicContact CE-CD2 4.31Å; M75-F165 HydrophobicContact CG-CB 4.13Å; M75-F165 HydrophobicContact CG-CD2 4.21Å; M75-F165 HydrophobicContact CG-CG 4.32Å
76Q94.7Very high95Very high47 Ų4739.5 Ų39.522%0.2219%0.188CC..THydrogen-bonded Turntrans-60.9-26.2175.966.1177.4-24.900113.2L72 Q73 I74 F86 F364L72-Q76 WeakPolarHBondContact O-CG 3.42Å; L72-Q76 PolarHBondContact O-N 2.81Å; Q73-Q76 VanDerWaalsContact O-CG 3.28Å; Q73-Q76 WeakPolarHBondContact O-CG 3.35Å; I74-Q76 PolarHBondContact O-N 3.31Å; Q76-F86 HydrophobicContact CB-CD1 4.33Å; Q76-F86 HydrophobicContact CB-CE1 4.34Å; Q76-F364 HydrophobicContact CB-CD1 4.49Å; Q76-F364 HydrophobicContact CB-CD2 3.77Å; Q76-F364 HydrophobicContact CB-CE1 4.43Å; Q76-F364 HydrophobicContact CB-CE2 3.75Å; Q76-F364 HydrophobicContact CB-CG 4.15Å; Q76-F364 HydrophobicContact CB-CZ 4.08Å
77N94Very high95.4Very high102 Ų10231 Ų3155%0.54516%0.156SC..THydrogen-bonded Turntrans-97.14.3-177.9-67.4-63.8000113.1Q73 I74 M75 Y136Q73-N77 PolarHBondContact O-ND2 3.02Å; I74-N77 PolarHBondContact O-N 3.2Å; I74-N77 VanDerWaalsContact O-N 3.09Å; M75-N77 PolarHBondContact O-N 3.26Å; N77-Y136 PolarHBondContact O-OH 3.19Å
78L97.1Very high95.7Very high7 Ų727.7 Ų27.74%0.03714%0.138CC..  trans-108.4137.3179.5-58.1-179.6000110.9I74 M75 L83 Y136 L137 K140 I142 F165 R366I74-L78 HydrophobicContact CG2-CD1 3.8Å; I74-L78 HydrophobicContact CG2-CG 4.44Å; I74-L78 WeakPolarHBondContact O-CG 3.38Å; M75-L78 PolarHBondContact O-N 2.87Å; L78-L83 HydrophobicContact CB-CD1 4.21Å; L78-L83 HydrophobicContact CD1-CD1 4.32Å; L78-Y136 HydrophobicContact CB-CE1 4.27Å; L78-Y136 HydrophobicContact CD2-CE1 3.82Å; L78-L137 HydrophobicContact CD1-CD2 3.75Å; L78-L137 HydrophobicContact CD2-CD2 4.03Å; L78-K140 HydrophobicContact CD2-CB 4.03Å; L78-K140 HydrophobicContact CD2-CG 3.94Å; L78-I142 HydrophobicContact CD1-CD1 4.11Å; L78-I142 HydrophobicContact CD2-CD1 3.39Å; L78-I142 HydrophobicContact CG-CD1 4.08Å; L78-F165 HydrophobicContact CD1-CD1 4.08Å; L78-F165 HydrophobicContact CD1-CE1 3.61Å; L78-F165 HydrophobicContact CD1-CE2 4.39Å; L78-F165 HydrophobicContact CD1-CZ 3.79Å; L78-R366 PolarHBondContact O-NH1 3.22Å; L78-R366 PolarHBondContact O-NH2 3.14Å
79E97.5Very high95.9Very high82 Ų8227.6 Ų27.638%0.38314%0.137SC..  trans-153.8116.8169.6-167.2165.9164.200108.9N85 Y136 R366 R370E79-N85 VanDerWaalsContact CA-OD1 3.3Å; E79-N85 WeakPolarHBondContact CA-OD1 3.3Å; E79-Y136 PolarHBondContact N-OH 2.73Å; E79-Y136 VanDerWaalsContact N-OH 3.12Å; E79-R366 IonicContact OE2-CZ 3.05Å; E79-R366 IonicContact OE2-NH1 3.11Å; E79-R366 PolarHBondContact OE2-NH1 2.93Å; E79-R370 IonicContact OE1-CZ 3.06Å; E79-R370 IonicContact OE1-NE 3.25Å; E79-R370 IonicContact OE1-NH2 2.56Å; E79-R370 PolarHBondContact OE1-NH2 3.11Å
80H98.6Very high96.1Very high21 Ų2126.5 Ų26.510%0.09713%0.131CC..  trans-158.7145.6-178.4-172.1-98.7000111.3F82 L83 N85 A133 Y136H80-F82 AromaticContact CE1-CD2 3.72Å; H80-F82 PolarHBondContact ND1-N 2.69Å; H80-F82 PolarHBondContact O-N 2.76Å; H80-F82 VanDerWaalsContact O-N 3.11Å; H80-L83 HydrophobicContact CB-CB 4.19Å; H80-L83 HydrophobicContact CB-CD1 3.82Å; H80-L83 HydrophobicContact CB-CG 3.8Å; H80-L83 PolarHBondContact O-N 3.31Å; H80-L83 VanDerWaalsContact O-N 3.11Å; H80-N85 PolarHBondContact N-OD1 3.37Å; H80-N85 PolarHBondContact O-ND2 3.17Å; H80-N85 PolarHBondContact O-OD1 3.31Å; H80-A133 PolarHBondContact CE1-N 3.19Å; H80-Y136 HydrophobicContact CB-CD1 3.72Å; H80-Y136 HydrophobicContact CB-CE1 3.98Å; H80-Y136 HydrophobicContact CB-CG 4.13Å; H80-Y136 AromaticContact CD2-CG 3.67Å
81P98.3Very high96.2Very high53 Ų5324.6 Ų24.634%0.34412%0.123SC..THydrogen-bonded Turntrans-58.8-25.9-177.2-27.336.1000115.5H161 L292 K294P81-H161 PolarHBondContact O-CD2 2.96Å; P81-H161 PolarHBondContact O-NE2 2.86Å; P81-H161 VanDerWaalsContact O-NE2 3.11Å; P81-L292 HydrophobicContact CG-CD1 4.07Å; P81-K294 VanDerWaalsContact O-CE 3.22Å; P81-K294 WeakPolarHBondContact O-CE 3.48Å; P81-K294 PolarHBondContact O-NZ 3.43Å
82F98.8Very high96.1Very high0 Ų027.2 Ų27.20%014%0.138CC..THydrogen-bonded Turntrans-110.220.2-178.5-57.3-57.6000113.3H80 E129 L132 A133 H159 V160 H161 L162 V291 K294H80-F82 AromaticContact CE1-CD2 3.72Å; H80-F82 PolarHBondContact ND1-N 2.69Å; H80-F82 PolarHBondContact O-N 2.76Å; H80-F82 VanDerWaalsContact O-N 3.11Å; F82-E129 HydrophobicContact CD1-CB 3.78Å; F82-E129 HydrophobicContact CD1-CG 4.07Å; F82-E129 HydrophobicContact CD2-CB 4.1Å; F82-E129 VanDerWaalsContact CD2-O 3.26Å; F82-E129 WeakPolarHBondContact CD2-O 3.34Å; F82-E129 HydrophobicContact CE1-CB 3.76Å; F82-E129 VanDerWaalsContact CE1-CD 3.49Å; F82-E129 HydrophobicContact CE1-CG 3.5Å; F82-E129 HydrophobicContact CE2-CB 4.11Å; F82-E129 HydrophobicContact CE2-CG 4.1Å; F82-E129 HydrophobicContact CG-CB 3.95Å; F82-E129 HydrophobicContact CZ-CB 3.92Å; F82-E129 HydrophobicContact CZ-CG 3.52Å; F82-L132 HydrophobicContact CD2-CB 4.09Å; F82-L132 HydrophobicContact CD2-CD1 4.25Å; F82-L132 HydrophobicContact CE2-CB 4.4Å; F82-L132 HydrophobicContact CE2-CD1 3.71Å; F82-A133 HydrophobicContact CB-CB 4.07Å; F82-H159 HydrophobicContact CE1-CB 4.35Å; F82-V160 WeakPolarHBondContact CD1-O 3.49Å; F82-H161 WeakPolarHBondContact O-CA 3.43Å; F82-L162 PolarHBondContact O-N 3Å; F82-V291 HydrophobicContact CE2-CG1 4.16Å; F82-V291 HydrophobicContact CZ-CG1 4.12Å; F82-V291 WeakPolarHBondContact CZ-O 3.49Å; F82-K294 HydrophobicContact CE1-CD 4.35Å; F82-K294 HydrophobicContact CE1-CG 3.78Å; F82-K294 HydrophobicContact CZ-CG 3.97Å
83L98.6Very high95.9Very high1 Ų134.4 Ų34.41%0.00517%0.171CC..BIsolated β-bridgetrans-114.2150.2167.1-64.9-176.6000109.2L78 H80 N85 A133 Y136 L137 L162 F165L78-L83 HydrophobicContact CB-CD1 4.21Å; L78-L83 HydrophobicContact CD1-CD1 4.32Å; H80-L83 HydrophobicContact CB-CB 4.19Å; H80-L83 HydrophobicContact CB-CD1 3.82Å; H80-L83 HydrophobicContact CB-CG 3.8Å; H80-L83 PolarHBondContact O-N 3.31Å; H80-L83 VanDerWaalsContact O-N 3.11Å; L83-N85 PolarHBondContact O-N 3.04Å; L83-N85 PolarHBondContact O-ND2 2.68Å; L83-N85 VanDerWaalsContact O-ND2 3.09Å; L83-A133 HydrophobicContact CD2-CB 3.94Å; L83-A133 HydrophobicContact CG-CB 4.47Å; L83-Y136 HydrophobicContact CD1-CD1 3.87Å; L83-Y136 HydrophobicContact CD1-CE1 3.93Å; L83-L137 HydrophobicContact CD1-CD2 3.96Å; L83-L162 HydrophobicContact CD2-CB 3.81Å; L83-L162 HydrophobicContact CD2-CD2 4.33Å; L83-L162 HydrophobicContact CD2-CG 4.46Å; L83-F165 HydrophobicContact CD1-CZ 4.27Å; L83-F165 HydrophobicContact CD2-CE2 4.47Å; L83-F165 HydrophobicContact CD2-CZ 3.91Å
84V98.1Very high95.7Very high4 Ų432.5 Ų32.52%0.02416%0.162CC..  trans-72.4105.1164.2171.60000108.1V100 D101 L103 L153 H161 L162V84-V100 HydrophobicContact CG1-CB 3.71Å; V84-V100 HydrophobicContact CG1-CG1 4.44Å; V84-V100 HydrophobicContact CG1-CG2 3.75Å; V84-D101 HydrophobicContact CG1-CB 4.29Å; V84-L103 HydrophobicContact CG2-CD1 3.59Å; V84-L103 HydrophobicContact CG2-CG 4.36Å; V84-L153 HydrophobicContact CG2-CD1 4.08Å; V84-H161 HydrophobicContact CG2-CB 4.02Å; V84-L162 PolarHBondContact N-O 3.41Å
85N97.6Very high95.6Very high22 Ų2233.5 Ų33.512%0.11817%0.168CC..  trans-79.6143.2-172.7-56.1-76.3000111.3E79 H80 L83 V100 D101E79-N85 VanDerWaalsContact CA-OD1 3.3Å; E79-N85 WeakPolarHBondContact CA-OD1 3.3Å; H80-N85 PolarHBondContact N-OD1 3.37Å; H80-N85 PolarHBondContact O-ND2 3.17Å; H80-N85 PolarHBondContact O-OD1 3.31Å; L83-N85 PolarHBondContact O-N 3.04Å; L83-N85 PolarHBondContact O-ND2 2.68Å; L83-N85 VanDerWaalsContact O-ND2 3.09Å; N85-V100 CarbonylContact O-C 3.38Å; N85-V100 VanDerWaalsContact O-CA 3.23Å; N85-V100 WeakPolarHBondContact O-CA 3.44Å; N85-V100 WeakPolarHBondContact O-CB 3.19Å; N85-D101 WeakPolarHBondContact CA-OD2 3.25Å; N85-D101 WeakPolarHBondContact CB-OD2 3.22Å; N85-D101 PolarHBondContact N-OD2 3.03Å; N85-D101 PolarHBondContact ND2-OD2 2.82Å; N85-D101 PolarHBondContact O-N 2.91Å
86F97.1Very high95.5Very high1 Ų133.1 Ų33.10%0.00417%0.166CC..EExtended strand (participates in β ladder)trans-94.3126.8-178.1174.2-115.1000111.6L72 M75 Q76 Y88 M98 V100 F364 R366L72-F86 HydrophobicContact CD2-CE1 4.21Å; L72-F86 HydrophobicContact CD2-CE2 3.9Å; L72-F86 HydrophobicContact CD2-CZ 3.47Å; L72-F86 VanDerWaalsContact CD2-CZ 3.47Å; M75-F86 HydrophobicContact CB-CB 3.81Å; M75-F86 HydrophobicContact CB-CD1 4.19Å; M75-F86 HydrophobicContact CB-CG 4.02Å; M75-F86 HydrophobicContact CE-CB 4.09Å; Q76-F86 HydrophobicContact CB-CD1 4.33Å; Q76-F86 HydrophobicContact CB-CE1 4.34Å; F86-Y88 WeakPolarHBondContact CE2-O 3.44Å; F86-Y88 WeakPolarHBondContact CZ-O 3.46Å; F86-M98 HydrophobicContact CD2-CE 4.43Å; F86-M98 HydrophobicContact CE2-CB 4.04Å; F86-M98 HydrophobicContact CE2-CE 4.34Å; F86-M98 HydrophobicContact CE2-CG 4.07Å; F86-V100 HydrophobicContact CB-CG1 4.4Å; F86-V100 HydrophobicContact CD2-CG1 3.93Å; F86-F364 AromaticContact CD1-CD1 3.47Å; F86-F364 HydrophobicContact CD1-CD1 3.47Å; F86-F364 VanDerWaalsContact CD1-CD1 3.47Å; F86-F364 AromaticContact CD1-CE1 3.64Å; F86-F364 HydrophobicContact CD1-CE1 3.64Å; F86-F364 HydrophobicContact CD1-CG 4.31Å; F86-F364 HydrophobicContact CE1-CB 3.82Å; F86-F364 AromaticContact CE1-CD1 3.16Å; F86-F364 HydrophobicContact CE1-CD1 3.16Å; F86-F364 AromaticContact CE1-CE1 3.85Å; F86-F364 HydrophobicContact CE1-CE1 3.85Å; F86-F364 AromaticContact CE1-CG 3.68Å; F86-F364 HydrophobicContact CE1-CG 3.68Å; F86-F364 HydrophobicContact CZ-CB 4.29Å; F86-F364 HydrophobicContact CZ-CD1 4.04Å; F86-R366 PolarHBondContact O-NE 3.19Å; F86-R366 PolarHBondContact O-NH2 3.2Å
87W97.1Very high95.5Very high18 Ų1831 Ų317%0.06816%0.156CC..EExtended strand (participates in β ladder)trans-107.8-44-172.6-72.684.8000113.7K47 Y49 V99 D101 R366 E367K47-W87 VanDerWaalsContact NZ-CH2 3.35Å; K47-W87 VanDerWaalsContact NZ-CZ2 3.28Å; Y49-W87 HydrophobicContact CD1-CB 4.47Å; Y49-W87 AromaticContact CD1-CD1 3.98Å; Y49-W87 HydrophobicContact CD1-CG 4.15Å; Y49-W87 HydrophobicContact CE1-CB 4.06Å; Y49-W87 AromaticContact CE1-CD1 3.73Å; Y49-W87 AromaticContact CE1-CD2 3.81Å; Y49-W87 HydrophobicContact CE1-CD2 3.81Å; Y49-W87 HydrophobicContact CE1-CE3 4.44Å; Y49-W87 AromaticContact CE1-CG 3.59Å; Y49-W87 HydrophobicContact CE1-CG 3.59Å; W87-V99 PolarHBondContact N-O 2.86Å; W87-D101 PolarHBondContact NE1-OD1 3.34Å; W87-R366 HydrophobicContact CE3-CB 4.16Å; W87-R366 PolarHBondContact O-N 2.9Å; W87-E367 HydrophobicContact CE3-CG 4.39Å; W87-E367 HydrophobicContact CZ3-CG 4.35Å
88Y96.8Very high95.6Very high0 Ų026.3 Ų26.30%013%0.131CC..EExtended strand (participates in β ladder)trans-144.4143.2-174.5-42.6-86000111.9V18 F23 Y49 F86 V99 F364 N365 E367V18-Y88 HydrophobicContact CB-CD1 4.23Å; V18-Y88 HydrophobicContact CG1-CD1 3.96Å; V18-Y88 HydrophobicContact CG1-CE1 4.4Å; V18-Y88 HydrophobicContact CG1-CG 4.24Å; V18-Y88 HydrophobicContact CG2-CD1 4.28Å; V18-Y88 HydrophobicContact CG2-CE1 4.24Å; F23-Y88 HydrophobicContact CE1-CD2 4.4Å; F23-Y88 HydrophobicContact CE1-CE2 4.37Å; F23-Y88 AromaticContact CZ-CD2 3.79Å; F23-Y88 HydrophobicContact CZ-CD2 3.79Å; F23-Y88 HydrophobicContact CZ-CE2 4.01Å; F23-Y88 HydrophobicContact CZ-CG 4.32Å; Y49-Y88 HydrophobicContact CE1-CE2 4.07Å; Y49-Y88 HydrophobicContact CE2-CE2 4.21Å; Y49-Y88 AromaticContact CZ-CE2 3.81Å; Y49-Y88 PolarHBondContact OH-OH 2.85Å; F86-Y88 WeakPolarHBondContact CE2-O 3.44Å; F86-Y88 WeakPolarHBondContact CZ-O 3.46Å; Y88-V99 HydrophobicContact CD2-CB 3.78Å; Y88-V99 HydrophobicContact CD2-CG1 3.71Å; Y88-V99 HydrophobicContact CD2-CG2 4.38Å; Y88-V99 HydrophobicContact CE2-CG1 4.35Å; Y88-V99 HydrophobicContact CG-CB 4.41Å; Y88-V99 PolarHBondContact N-O 2.77Å; Y88-V99 PolarHBondContact O-N 3.03Å; Y88-F364 CarbonylContact C-O 3.58Å; Y88-F364 VanDerWaalsContact CA-O 3.24Å; Y88-F364 WeakPolarHBondContact CA-O 3.16Å; Y88-N365 HydrophobicContact CD1-CB 4.25Å; Y88-N365 WeakPolarHBondContact CE1-OD1 3.28Å; Y88-E367 HydrophobicContact CE1-CG 4.18Å; Y88-E367 PolarHBondContact OH-OE1 3Å; Y88-E367 PolarHBondContact OH-OE2 2.88Å
89S96.4Very high95.6Very high1 Ų126 Ų261%0.00713%0.129CC..EExtended strand (participates in β ladder)trans-127.2141.7157.742.50000111F97 I362 V363 F364S89-F97 VanDerWaalsContact CA-O 3.3Å; S89-F97 WeakPolarHBondContact CA-O 3.48Å; S89-I362 PolarHBondContact OG-O 3.32Å; S89-V363 WeakPolarHBondContact O-CA 3.41Å; S89-V363 WeakPolarHBondContact O-CG1 3.46Å; S89-F364 PolarHBondContact N-O 3.43Å; S89-F364 PolarHBondContact O-N 3.12Å; S89-F364 VanDerWaalsContact OG-CB 3.23Å; S89-F364 WeakPolarHBondContact OG-CB 3.47Å; S89-F364 PolarHBondContact OG-N 2.88Å
90F95.6Very high95.6Very high7 Ų723.1 Ų23.13%0.03112%0.117CC..EExtended strand (participates in β ladder)trans-154173.817148.5-93.6000108.2V18 F20 F23 M51 F97 V99 F361V18-F90 HydrophobicContact CG1-CD1 4.38Å; V18-F90 HydrophobicContact CG1-CE1 4.3Å; V18-F90 WeakPolarHBondContact O-CD1 3.3Å; F20-F90 VanDerWaalsContact CA-CE2 3.43Å; F20-F90 HydrophobicContact CB-CD2 4.38Å; F20-F90 HydrophobicContact CB-CE2 3.78Å; F20-F90 HydrophobicContact CD2-CE2 4.28Å; F20-F90 VanDerWaalsContact N-CE2 3.26Å; F23-F90 HydrophobicContact CD2-CE1 4.1Å; F23-F90 AromaticContact CD2-CZ 3.84Å; F23-F90 HydrophobicContact CD2-CZ 3.84Å; F23-F90 AromaticContact CE2-CE1 3.53Å; F23-F90 HydrophobicContact CE2-CE1 3.53Å; F23-F90 AromaticContact CE2-CZ 3.77Å; F23-F90 HydrophobicContact CE2-CZ 3.77Å; F23-F90 HydrophobicContact CZ-CE1 4.33Å; M51-F90 HydrophobicContact CE-CE2 4.5Å; M51-F90 HydrophobicContact CE-CZ 3.69Å; M51-F90 HydrophobicContact SD-CZ 4.49Å; F90-F97 HydrophobicContact CD2-CB 3.7Å; F90-F97 AromaticContact CD2-CD2 3.49Å; F90-F97 HydrophobicContact CD2-CD2 3.49Å; F90-F97 VanDerWaalsContact CD2-CD2 3.49Å; F90-F97 HydrophobicContact CD2-CE2 4.36Å; F90-F97 AromaticContact CD2-CG 3.79Å; F90-F97 HydrophobicContact CD2-CG 3.79Å; F90-F97 HydrophobicContact CE1-CB 4.46Å; F90-F97 HydrophobicContact CE2-CB 3.41Å; F90-F97 VanDerWaalsContact CE2-CB 3.41Å; F90-F97 HydrophobicContact CE2-CD1 4.12Å; F90-F97 AromaticContact CE2-CD2 3.52Å; F90-F97 HydrophobicContact CE2-CD2 3.52Å; F90-F97 HydrophobicContact CE2-CE2 4.32Å; F90-F97 AromaticContact CE2-CG 3.4Å; F90-F97 HydrophobicContact CE2-CG 3.4Å; F90-F97 VanDerWaalsContact CE2-CG 3.4Å; F90-F97 HydrophobicContact CG-CB 4.35Å; F90-F97 HydrophobicContact CZ-CB 3.84Å; F90-F97 HydrophobicContact CZ-CG 4.22Å; F90-F97 PolarHBondContact N-O 2.7Å; F90-F97 WeakPolarHBondContact O-CB 3.48Å; F90-F97 PolarHBondContact O-N 3.46Å; F90-V99 HydrophobicContact CE1-CG2 3.85Å; F90-V99 HydrophobicContact CZ-CG2 4.14Å; F90-F361 VanDerWaalsContact C-CE1 3.45Å; F90-F361 WeakPolarHBondContact O-CE1 3.18Å; F90-F361 VanDerWaalsContact O-CZ 3.32Å; F90-F361 WeakPolarHBondContact O-CZ 3.21Å
91Q93.9Very high95.5Very high32 Ų3223.6 Ų23.615%0.1512%0.12CC..EExtended strand (participates in β ladder)trans-143.9156.7-18058.6176.9-21.900109.6D95 M96 Q358 F361Q91-D95 WeakPolarHBondContact CA-O 3.3Å; Q91-M96 HydrophobicContact CB-CG 4.39Å; Q91-Q358 PolarHBondContact NE2-O 3.09Å; Q91-Q358 VanDerWaalsContact OE1-OE1 3.11Å; Q91-F361 HydrophobicContact CB-CD1 4.12Å; Q91-F361 HydrophobicContact CB-CE1 4.15Å; Q91-F361 HydrophobicContact CB-CG 4.34Å; Q91-F361 HydrophobicContact CB-CZ 4.4Å; Q91-F361 VanDerWaalsContact CD-CB 3.5Å; Q91-F361 HydrophobicContact CG-CB 4.49Å; Q91-F361 HydrophobicContact CG-CD1 3.85Å; Q91-F361 HydrophobicContact CG-CE1 4.3Å; Q91-F361 HydrophobicContact CG-CG 4.16Å; Q91-F361 VanDerWaalsContact NE2-CB 3.27Å
92D91.5Very high95.4Very high61 Ų6122.3 Ų22.333%0.32611%0.11SC..  trans-122.3-164.1166.570.117.5000110.3K56 E94 D95 F97K56-D92 VanDerWaalsContact CE-O 3.25Å; K56-D92 WeakPolarHBondContact CE-O 3.4Å; K56-D92 PolarHBondContact NZ-O 2.89Å; D92-E94 VanDerWaalsContact C-N 3.3Å; D92-E94 PolarHBondContact O-N 3.25Å; D92-E94 PolarHBondContact OD1-N 3.49Å; D92-D95 PolarHBondContact N-O 2.83Å; D92-D95 PolarHBondContact OD1-N 3.44Å; D92-F97 HydrophobicContact CB-CE2 4.2Å
93E88.1Confident95.1Very high155 Ų15523.5 Ų23.572%0.72412%0.117SC*.SBendtrans-63-32.4-180-64.3171.7-177.900113.3
94E89.4Confident94.7Very high57 Ų5727.3 Ų27.327%0.26614%0.137SC..SBendtrans-103.9-36.5-171.7-64.3-170167.500112.8N55 K56 D92 K328 L332N55-E94 PolarHBondContact ND2-O 2.81Å; K56-E94 WeakPolarHBondContact CB-O 3.23Å; K56-E94 WeakPolarHBondContact CG-O 3.42Å; K56-E94 PolarHBondContact N-O 3.25Å; D92-E94 VanDerWaalsContact C-N 3.3Å; D92-E94 PolarHBondContact O-N 3.25Å; D92-E94 PolarHBondContact OD1-N 3.49Å; E94-K328 IonicContact OE2-NZ 2.68Å; E94-K328 PolarHBondContact OE2-NZ 3.26Å; E94-L332 WeakPolarHBondContact OE1-CD1 3.35Å; E94-L332 WeakPolarHBondContact OE1-CD2 3.41Å
95D92.4Very high94.5Very high24 Ų2427.2 Ų27.213%0.12814%0.136CC..EExtended strand (participates in β ladder)trans-134.5151.8-162.8-62.1-52.7000112.6M54 N55 Q91 D92 F97M54-D95 WeakPolarHBondContact O-CA 3.08Å; N55-D95 WeakPolarHBondContact CA-OD1 3.49Å; N55-D95 WeakPolarHBondContact CB-OD1 3.47Å; N55-D95 PolarHBondContact ND2-OD1 2.77Å; N55-D95 VanDerWaalsContact ND2-OD1 3.14Å; Q91-D95 WeakPolarHBondContact CA-O 3.3Å; D92-D95 PolarHBondContact N-O 2.83Å; D92-D95 PolarHBondContact OD1-N 3.44Å; D95-F97 HydrophobicContact CB-CE1 4.17Å; D95-F97 HydrophobicContact CB-CE2 3.91Å; D95-F97 HydrophobicContact CB-CZ 3.62Å; D95-F97 WeakPolarHBondContact O-CE2 3.32Å
96M94.4Very high94.2Very high0 Ų026.6 Ų26.60%014%0.135CC..EExtended strand (participates in β ladder)trans-102.7139.7166-67.8175.2-66.100109Y53 M54 K56 C59 V68 Q91 V357 F361Y53-M96 CarbonylContact C-O 3.6Å; Y53-M96 WeakPolarHBondContact CA-O 3.49Å; M54-M96 HydrophobicContact CB-CB 4.48Å; M54-M96 HydrophobicContact CB-CE 4.36Å; M54-M96 HydrophobicContact CE-CB 4.19Å; M54-M96 PolarHBondContact N-O 3.31Å; M54-M96 PolarHBondContact O-N 3.16Å; K56-M96 HydrophobicContact CG-CG 3.94Å; C59-M96 HydrophobicContact CB-CE 4.11Å; V68-M96 HydrophobicContact CB-CE 4.49Å; V68-M96 HydrophobicContact CG1-CE 4.03Å; V68-M96 HydrophobicContact CG1-SD 4.21Å; Q91-M96 HydrophobicContact CB-CG 4.39Å; M96-V357 HydrophobicContact CE-CG1 4.47Å; M96-V357 HydrophobicContact CG-CG1 4.31Å; M96-V357 HydrophobicContact SD-CG1 3.57Å; M96-V357 VanDerWaalsContact SD-CG1 3.57Å; M96-F361 HydrophobicContact CB-CD2 4.33Å; M96-F361 HydrophobicContact CB-CE2 3.62Å; M96-F361 HydrophobicContact CB-CZ 4.24Å; M96-F361 HydrophobicContact CG-CD2 3.73Å; M96-F361 HydrophobicContact CG-CE2 3.54Å; M96-F361 HydrophobicContact CG-CZ 4.45Å; M96-F361 HydrophobicContact SD-CD2 3.67Å; M96-F361 HydrophobicContact SD-CE2 3.77Å
97F94.6Very high94.1Very high4 Ų428.4 Ų28.42%0.01815%0.145CC..EExtended strand (participates in β ladder)trans-120.8135.7-175-55.8-89.8000111.5F20 M51 K52 S89 F90 D92 D95F20-F97 AromaticContact CD2-CD1 3.9Å; F20-F97 HydrophobicContact CD2-CD1 3.9Å; F20-F97 AromaticContact CD2-CE1 3.41Å; F20-F97 HydrophobicContact CD2-CE1 3.41Å; F20-F97 VanDerWaalsContact CD2-CE1 3.41Å; F20-F97 HydrophobicContact CD2-CE2 4.35Å; F20-F97 AromaticContact CD2-CZ 3.66Å; F20-F97 HydrophobicContact CD2-CZ 3.66Å; F20-F97 HydrophobicContact CE2-CD1 4.27Å; F20-F97 AromaticContact CE2-CE1 3.6Å; F20-F97 HydrophobicContact CE2-CE1 3.6Å; F20-F97 HydrophobicContact CE2-CZ 4.12Å; F20-F97 HydrophobicContact CG-CE1 4.46Å; F20-F97 HydrophobicContact CG-CZ 4.32Å; M51-F97 HydrophobicContact CG-CD1 4.28Å; M51-F97 HydrophobicContact SD-CD1 3.7Å; M51-F97 HydrophobicContact SD-CE1 4.39Å; M51-F97 HydrophobicContact SD-CG 4.5Å; K52-F97 WeakPolarHBondContact O-CA 3.37Å; S89-F97 VanDerWaalsContact CA-O 3.3Å; S89-F97 WeakPolarHBondContact CA-O 3.48Å; F90-F97 HydrophobicContact CD2-CB 3.7Å; F90-F97 AromaticContact CD2-CD2 3.49Å; F90-F97 HydrophobicContact CD2-CD2 3.49Å; F90-F97 VanDerWaalsContact CD2-CD2 3.49Å; F90-F97 HydrophobicContact CD2-CE2 4.36Å; F90-F97 AromaticContact CD2-CG 3.79Å; F90-F97 HydrophobicContact CD2-CG 3.79Å; F90-F97 HydrophobicContact CE1-CB 4.46Å; F90-F97 HydrophobicContact CE2-CB 3.41Å; F90-F97 VanDerWaalsContact CE2-CB 3.41Å; F90-F97 HydrophobicContact CE2-CD1 4.12Å; F90-F97 AromaticContact CE2-CD2 3.52Å; F90-F97 HydrophobicContact CE2-CD2 3.52Å; F90-F97 HydrophobicContact CE2-CE2 4.32Å; F90-F97 AromaticContact CE2-CG 3.4Å; F90-F97 HydrophobicContact CE2-CG 3.4Å; F90-F97 VanDerWaalsContact CE2-CG 3.4Å; F90-F97 HydrophobicContact CG-CB 4.35Å; F90-F97 HydrophobicContact CZ-CB 3.84Å; F90-F97 HydrophobicContact CZ-CG 4.22Å; F90-F97 PolarHBondContact N-O 2.7Å; F90-F97 WeakPolarHBondContact O-CB 3.48Å; F90-F97 PolarHBondContact O-N 3.46Å; D92-F97 HydrophobicContact CB-CE2 4.2Å; D95-F97 HydrophobicContact CB-CE1 4.17Å; D95-F97 HydrophobicContact CB-CE2 3.91Å; D95-F97 HydrophobicContact CB-CZ 3.62Å; D95-F97 WeakPolarHBondContact O-CE2 3.32Å
98M95.3Very high94.1Very high3 Ų327.6 Ų27.62%0.01514%0.142CC..EExtended strand (participates in β ladder)trans-122.4126.2170.1-72.2172.972.800109M51 K52 M54 E71 L72 M75 F86M51-M98 CarbonylContact C-O 3.56Å; M51-M98 VanDerWaalsContact CA-O 3.29Å; M51-M98 WeakPolarHBondContact CA-O 3.35Å; K52-M98 HydrophobicContact CB-CB 4.31Å; K52-M98 HydrophobicContact CD-SD 4.39Å; K52-M98 PolarHBondContact N-O 3.15Å; K52-M98 PolarHBondContact O-N 2.93Å; M54-M98 HydrophobicContact CE-CB 4.35Å; M54-M98 HydrophobicContact CE-CG 3.63Å; M54-M98 HydrophobicContact CE-SD 3.5Å; M54-M98 VanDerWaalsContact CE-SD 3.5Å; M54-M98 HydrophobicContact SD-SD 4.2Å; E71-M98 HydrophobicContact CG-CE 4.03Å; L72-M98 HydrophobicContact CD2-CE 4.06Å; L72-M98 HydrophobicContact CD2-CG 3.54Å; L72-M98 HydrophobicContact CD2-SD 3.97Å; L72-M98 HydrophobicContact CG-CG 4.35Å; L72-M98 HydrophobicContact CG-SD 4.26Å; M75-M98 HydrophobicContact SD-CE 3.4Å; M75-M98 WeakPolarHBondContact SD-CE 3.29Å; F86-M98 HydrophobicContact CD2-CE 4.43Å; F86-M98 HydrophobicContact CE2-CB 4.04Å; F86-M98 HydrophobicContact CE2-CE 4.34Å; F86-M98 HydrophobicContact CE2-CG 4.07Å
99V96.9Very high94Very high0 Ų029.4 Ų29.40%015%0.149CC..EExtended strand (participates in β ladder)trans-113.9122.8178.3-174.30000109F23 Y49 A50 M51 W87 Y88 F90F23-V99 HydrophobicContact CE1-CG1 4.1Å; F23-V99 HydrophobicContact CE1-CG2 4.48Å; F23-V99 HydrophobicContact CE2-CG2 4.46Å; F23-V99 HydrophobicContact CZ-CG1 4.34Å; F23-V99 HydrophobicContact CZ-CG2 4.18Å; Y49-V99 VanDerWaalsContact CB-CG1 3.43Å; Y49-V99 HydrophobicContact CD1-CG1 3.91Å; Y49-V99 HydrophobicContact CD2-CG1 4.31Å; Y49-V99 HydrophobicContact CG-CG1 3.64Å; A50-V99 WeakPolarHBondContact O-CA 3.42Å; M51-V99 HydrophobicContact CB-CG2 4.4Å; M51-V99 HydrophobicContact CE-CG2 3.77Å; M51-V99 HydrophobicContact CG-CG2 4.1Å; W87-V99 PolarHBondContact N-O 2.86Å; Y88-V99 HydrophobicContact CD2-CB 3.78Å; Y88-V99 HydrophobicContact CD2-CG1 3.71Å; Y88-V99 HydrophobicContact CD2-CG2 4.38Å; Y88-V99 HydrophobicContact CE2-CG1 4.35Å; Y88-V99 HydrophobicContact CG-CB 4.41Å; Y88-V99 PolarHBondContact N-O 2.77Å; Y88-V99 PolarHBondContact O-N 3.03Å; F90-V99 HydrophobicContact CE1-CG2 3.85Å; F90-V99 HydrophobicContact CZ-CG2 4.14Å
100V97.3Very high93.9Very high22 Ų2231.3 Ų31.313%0.13316%0.156CC..EExtended strand (participates in β ladder)trans-130.9171.8-173.8-60.10000111.2Y49 A50 M75 V84 N85 F86 L102Y49-V100 WeakPolarHBondContact CB-O 3.47Å; A50-V100 HydrophobicContact CB-CG2 3.95Å; A50-V100 PolarHBondContact N-O 2.87Å; A50-V100 PolarHBondContact O-N 3.07Å; M75-V100 HydrophobicContact CE-CG1 4.01Å; V84-V100 HydrophobicContact CG1-CB 3.71Å; V84-V100 HydrophobicContact CG1-CG1 4.44Å; V84-V100 HydrophobicContact CG1-CG2 3.75Å; N85-V100 CarbonylContact O-C 3.38Å; N85-V100 VanDerWaalsContact O-CA 3.23Å; N85-V100 WeakPolarHBondContact O-CA 3.44Å; N85-V100 WeakPolarHBondContact O-CB 3.19Å; F86-V100 HydrophobicContact CB-CG1 4.4Å; F86-V100 HydrophobicContact CD2-CG1 3.93Å; V100-L102 PolarHBondContact O-N 3.09Å
101D97Very high93.9Very high30 Ų3031.3 Ų31.316%0.1616%0.156CC..EExtended strand (participates in β ladder)trans-49.7137.4171.2-70.7-31.2000111.8V84 N85 W87V84-D101 HydrophobicContact CG1-CB 4.29Å; N85-D101 WeakPolarHBondContact CA-OD2 3.25Å; N85-D101 WeakPolarHBondContact CB-OD2 3.22Å; N85-D101 PolarHBondContact N-OD2 3.03Å; N85-D101 PolarHBondContact ND2-OD2 2.82Å; N85-D101 PolarHBondContact O-N 2.91Å; W87-D101 PolarHBondContact NE1-OD1 3.34Å
102L95.6Very high93.9Very high26 Ų2630.6 Ų30.614%0.13615%0.153CC..  trans-91.4117.7171.5177.460.1000109.8I29 I39 M48 A50 V100 L104I29-L102 HydrophobicContact CD1-CD1 4.1Å; I39-L102 HydrophobicContact CD1-CD1 4.35Å; I39-L102 HydrophobicContact CG1-CD1 3.81Å; I39-L102 HydrophobicContact CG1-CD2 4.29Å; I39-L102 HydrophobicContact CG2-CD2 3.86Å; M48-L102 HydrophobicContact CB-CD2 3.81Å; M48-L102 HydrophobicContact CE-CD2 4.29Å; A50-L102 HydrophobicContact CB-CD1 4.19Å; V100-L102 PolarHBondContact O-N 3.09Å; L102-L104 HydrophobicContact CD1-CD2 4.08Å; L102-L104 HydrophobicContact CD2-CD2 3.84Å; L102-L104 HydrophobicContact CD2-CG 4.42Å; L102-L104 HydrophobicContact CG-CD2 3.85Å; L102-L104 HydrophobicContact CG-CG 4.23Å
103L94.4Very high94Very high26 Ų2633.4 Ų33.414%0.13616%0.164CC..  trans-111.7112.4175.4-59.7-172.2000110.4V84 L153 L154 D155 H161V84-L103 HydrophobicContact CG2-CD1 3.59Å; V84-L103 HydrophobicContact CG2-CG 4.36Å; L103-L153 HydrophobicContact CB-CB 4.08Å; L103-L153 HydrophobicContact CB-CD1 4.25Å; L103-L153 HydrophobicContact CD1-CB 3.62Å; L103-L153 HydrophobicContact CD1-CD1 4.24Å; L103-L153 HydrophobicContact CG-CB 4.48Å; L103-L154 WeakPolarHBondContact CB-O 3.47Å; L103-D155 HydrophobicContact CD2-CB 4.01Å; L103-H161 HydrophobicContact CD1-CB 3.36Å
104L89.7Confident94.2Very high81 Ų8131.2 Ų31.242%0.42415%0.154SC..THydrogen-bonded Turntrans-85.9-11.2-171.3-64.8175.8000113.7I39 L102 G106 N308I39-L104 HydrophobicContact CD1-CD2 4.44Å; L102-L104 HydrophobicContact CD1-CD2 4.08Å; L102-L104 HydrophobicContact CD2-CD2 3.84Å; L102-L104 HydrophobicContact CD2-CG 4.42Å; L102-L104 HydrophobicContact CG-CD2 3.85Å; L102-L104 HydrophobicContact CG-CG 4.23Å; L104-G106 PolarHBondContact O-N 3Å; L104-N308 PolarHBondContact O-ND2 3.22Å
105G92.7Very high94.3Very high1 Ų134.4 Ų34.41%0.0117%0.173CC..THydrogen-bonded Turntrans-74-9179.600000113.9H111 L154 N308G105-H111 PolarHBondContact O-NE2 2.85Å; G105-L154 WeakPolarHBondContact CA-O 3.4Å; G105-L154 PolarHBondContact N-O 3.19Å; G105-N308 VanDerWaalsContact O-CB 3.29Å; G105-N308 WeakPolarHBondContact O-CB 3.19Å
106G92.7Very high94.4Very high10 Ų1034.9 Ų34.910%0.10318%0.177CC..  trans76.2177.9-179.400000113.1L104 L153 L154 N308L104-G106 PolarHBondContact O-N 3Å; G106-L153 CarbonylContact O-C 3.48Å; G106-L153 WeakPolarHBondContact O-CA 3.48Å; G106-L154 PolarHBondContact O-N 3.38Å; G106-N308 VanDerWaalsContact CA-O 3.27Å; G106-N308 WeakPolarHBondContact CA-O 3.43Å
107D94.4Very high94.2Very high39 Ų3943 Ų4321%0.20921%0.214CC..BIsolated β-bridgetrans-83.3153.2175.961.984.3000112.3R109 Y110 H111 I152 L153D107-R109 PolarHBondContact O-N 3.37Å; D107-R109 WeakPolarHBondContact OD1-CA 3.45Å; D107-R109 WeakPolarHBondContact OD1-CB 3.28Å; D107-R109 PolarHBondContact OD1-N 3.43Å; D107-R109 VanDerWaalsContact OD1-N 3.14Å; D107-Y110 WeakPolarHBondContact O-CB 3.3Å; D107-Y110 PolarHBondContact O-N 2.94Å; D107-Y110 PolarHBondContact OD1-N 3.09Å; D107-H111 PolarHBondContact O-CD2 2.84Å; D107-I152 CarbonylContact C-O 3.6Å; D107-I152 WeakPolarHBondContact CA-O 3.28Å; D107-L153 HydrophobicContact CB-CD2 3.56Å
108L96.9Very high94.4Very high0 Ų043.4 Ų43.40%022%0.216CC..Hα-helixtrans-65.5-24.2178.8-72.7-177.2000113H111 L112 F118 Y126 P149 I152 L154 V160 L218L108-H111 PolarHBondContact O-N 3.19Å; L108-L112 WeakPolarHBondContact O-CG 3.48Å; L108-L112 PolarHBondContact O-N 2.97Å; L108-F118 HydrophobicContact CD2-CE1 4.31Å; L108-F118 HydrophobicContact CD2-CZ 3.98Å; L108-Y126 HydrophobicContact CD1-CD2 4.41Å; L108-Y126 HydrophobicContact CD1-CE2 4.49Å; L108-Y126 HydrophobicContact CD2-CE2 4.06Å; L108-P149 HydrophobicContact CB-CB 3.88Å; L108-P149 PolarHBondContact N-O 3.35Å; L108-P149 VanDerWaalsContact N-O 3.1Å; L108-I152 HydrophobicContact CD1-CB 3.81Å; L108-I152 HydrophobicContact CD1-CD1 4.32Å; L108-I152 HydrophobicContact CD1-CG2 3.42Å; L108-I152 VanDerWaalsContact CD1-CG2 3.42Å; L108-I152 HydrophobicContact CG-CB 4.17Å; L108-I152 HydrophobicContact CG-CG2 3.95Å; L108-I152 PolarHBondContact N-O 2.96Å; L108-L154 HydrophobicContact CD2-CD1 3.72Å; L108-L154 HydrophobicContact CD2-CD2 3.99Å; L108-L154 HydrophobicContact CD2-CG 3.86Å; L108-V160 HydrophobicContact CD1-CG1 4.08Å; L108-L218 HydrophobicContact CB-CD2 4.16Å; L108-L218 HydrophobicContact CD1-CD1 3.83Å; L108-L218 HydrophobicContact CD1-CD2 4Å; L108-L218 HydrophobicContact CD2-CD2 4.38Å; L108-L218 HydrophobicContact CG-CD2 4.44Å
109R95.4Very high94.5Very high39 Ų3945.7 Ų45.715%0.14723%0.232CC..Hα-helixtrans-63.3-44.7174.8166.466.162.2-148.4-8.8110.9D107 H111 L112 Q113 P149 D150 Y186 E217D107-R109 PolarHBondContact O-N 3.37Å; D107-R109 WeakPolarHBondContact OD1-CA 3.45Å; D107-R109 WeakPolarHBondContact OD1-CB 3.28Å; D107-R109 PolarHBondContact OD1-N 3.43Å; D107-R109 VanDerWaalsContact OD1-N 3.14Å; R109-H111 VanDerWaalsContact C-N 3.3Å; R109-H111 PolarHBondContact O-N 3.19Å; R109-L112 WeakPolarHBondContact O-CB 3.42Å; R109-L112 PolarHBondContact O-N 2.88Å; R109-Q113 WeakPolarHBondContact O-CG 3.15Å; R109-Q113 PolarHBondContact O-N 2.83Å; R109-P149 HydrophobicContact CB-CB 4.05Å; R109-P149 PolarHBondContact N-O 2.87Å; R109-D150 HydrophobicContact CB-CB 4.21Å; R109-D150 WeakPolarHBondContact CG-OD1 3.37Å; R109-D150 IonicContact CZ-OD2 2.72Å; R109-D150 IonicContact NE-OD1 3.19Å; R109-D150 IonicContact NE-OD2 2.83Å; R109-D150 PolarHBondContact NE-OD2 3.29Å; R109-D150 VanDerWaalsContact NE-OD2 3.11Å; R109-D150 IonicContact NH2-OD2 3.69Å; R109-D150 PolarHBondContact NH2-OD2 2.88Å; R109-Y186 PolarHBondContact NH2-OH 3.14Å; R109-E217 IonicContact CZ-OE1 3.52Å; R109-E217 IonicContact NH1-OE1 3.14Å; R109-E217 PolarHBondContact NH1-OE1 2.83Å; R109-E217 IonicContact NH2-OE1 3.87Å; R109-E217 PolarHBondContact NH2-OE1 3.29Å; R109-E217 IonicContact NH2-OE2 3.34Å
110Y93.4Very high94.5Very high40 Ų4047.8 Ų47.816%0.15724%0.242CC..Hα-helixtrans-55.3-47.7176.3173.6-95.3000110.7D107 L112 Q113 Q114 N308D107-Y110 WeakPolarHBondContact O-CB 3.3Å; D107-Y110 PolarHBondContact O-N 2.94Å; D107-Y110 PolarHBondContact OD1-N 3.09Å; Y110-L112 PolarHBondContact O-N 3.26Å; Y110-Q113 WeakPolarHBondContact O-CB 3.23Å; Y110-Q113 PolarHBondContact O-N 2.85Å; Y110-Q113 VanDerWaalsContact O-N 3.11Å; Y110-Q114 HydrophobicContact CD1-CG 4.29Å; Y110-Q114 HydrophobicContact CE1-CG 3.85Å; Y110-Q114 HydrophobicContact CE2-CG 4.33Å; Y110-Q114 WeakPolarHBondContact O-CG 3.46Å; Y110-Q114 PolarHBondContact O-N 2.86Å; Y110-N308 HydrophobicContact CD1-CB 4.05Å; Y110-N308 WeakPolarHBondContact CD1-O 3.43Å; Y110-N308 HydrophobicContact CE1-CB 3.91Å
111H95Very high94.5Very high7 Ų750.7 Ų50.73%0.03226%0.263CS..Hα-helixtrans-63.7-39.6179.4-67.1-67.2000112.8G105 D107 L108 R109 Q113 Q114 N115 V116 F118 F300G105-H111 PolarHBondContact O-NE2 2.85Å; D107-H111 PolarHBondContact O-CD2 2.84Å; L108-H111 PolarHBondContact O-N 3.19Å; R109-H111 VanDerWaalsContact C-N 3.3Å; R109-H111 PolarHBondContact O-N 3.19Å; H111-Q113 VanDerWaalsContact C-N 3.33Å; H111-Q113 PolarHBondContact O-N 3.11Å; H111-Q114 PolarHBondContact O-N 3.11Å; H111-N115 PolarHBondContact O-N 2.96Å; H111-V116 HydrophobicContact CB-CB 4.14Å; H111-V116 HydrophobicContact CB-CG2 4.01Å; H111-V116 VanDerWaalsContact O-CB 3.28Å; H111-V116 WeakPolarHBondContact O-CB 3.44Å; H111-V116 WeakPolarHBondContact O-CG2 3.44Å; H111-V116 PolarHBondContact O-N 3.08Å; H111-F118 HydrophobicContact CB-CE2 4.33Å; H111-F118 HydrophobicContact CB-CZ 3.8Å; H111-F300 AromaticContact CE1-CE1 3.85Å; H111-F300 AromaticContact CE1-CZ 3.8Å; H111-F300 AromaticContact ND1-CE1 3.75Å; H111-F300 AromaticContact ND1-CZ 3.43Å; H111-F300 WeakPolarHBondContact ND1-CZ 3.28Å
112L95.1Very high94.6Very high18 Ų1849.4 Ų49.49%0.09426%0.257CS..Hα-helixtrans-59.8-42.1171.6-76.9170.8000112.2L108 R109 Y110 Q114 N115 P149 E217 L218L108-L112 WeakPolarHBondContact O-CG 3.48Å; L108-L112 PolarHBondContact O-N 2.97Å; R109-L112 WeakPolarHBondContact O-CB 3.42Å; R109-L112 PolarHBondContact O-N 2.88Å; Y110-L112 PolarHBondContact O-N 3.26Å; L112-Q114 VanDerWaalsContact C-N 3.27Å; L112-Q114 PolarHBondContact O-N 3.36Å; L112-N115 WeakPolarHBondContact O-CA 3.35Å; L112-N115 PolarHBondContact O-N 2.8Å; L112-P149 HydrophobicContact CD1-CB 3.89Å; L112-P149 HydrophobicContact CD1-CG 3.81Å; L112-E217 HydrophobicContact CD1-CG 3.91Å; L112-L218 HydrophobicContact CD1-CD2 4.16Å; L112-L218 HydrophobicContact CD2-CD2 4.33Å; L112-L218 HydrophobicContact CG-CD2 4.17Å
113Q93.9Very high94.7Very high119 Ų11948.2 Ų48.256%0.55625%0.25SS*.Hα-helixtrans-66.7-28.2177.4-70.2172-13.700112.8R109 Y110 H111 N115R109-Q113 WeakPolarHBondContact O-CG 3.15Å; R109-Q113 PolarHBondContact O-N 2.83Å; Y110-Q113 WeakPolarHBondContact O-CB 3.23Å; Y110-Q113 PolarHBondContact O-N 2.85Å; Y110-Q113 VanDerWaalsContact O-N 3.11Å; H111-Q113 VanDerWaalsContact C-N 3.33Å; H111-Q113 PolarHBondContact O-N 3.11Å; Q113-N115 PolarHBondContact O-N 2.84Å
114Q91.7Very high94.9Very high110 Ų11048 Ų4851%0.51425%0.248SC..THydrogen-bonded Turntrans-79.78.4171.3-60.1-50.4-55.700113.2Y110 H111 L112 V116Y110-Q114 HydrophobicContact CD1-CG 4.29Å; Y110-Q114 HydrophobicContact CE1-CG 3.85Å; Y110-Q114 HydrophobicContact CE2-CG 4.33Å; Y110-Q114 WeakPolarHBondContact O-CG 3.46Å; Y110-Q114 PolarHBondContact O-N 2.86Å; H111-Q114 PolarHBondContact O-N 3.11Å; L112-Q114 VanDerWaalsContact C-N 3.27Å; L112-Q114 PolarHBondContact O-N 3.36Å; Q114-V116 HydrophobicContact CB-CG2 4.39Å; Q114-V116 PolarHBondContact O-N 3.12Å
115N92.6Very high95.4Very high124 Ų12445.1 Ų45.166%0.66323%0.233SC*.THydrogen-bonded Turntrans5833-176.9-54-71.4000113.3H111 L112 Q113 H117H111-N115 PolarHBondContact O-N 2.96Å; L112-N115 WeakPolarHBondContact O-CA 3.35Å; L112-N115 PolarHBondContact O-N 2.8Å; Q113-N115 PolarHBondContact O-N 2.84Å; N115-H117 PolarHBondContact O-CE1 3.37Å; N115-H117 PolarHBondContact O-N 3.18Å; N115-H117 PolarHBondContact O-ND1 3.4Å
116V94.1Very high95.7Very high34 Ų3445.2 Ų45.221%0.20623%0.233CC..  trans-64.7130.1170.21750000108.8H111 Q114 F118 F300H111-V116 HydrophobicContact CB-CB 4.14Å; H111-V116 HydrophobicContact CB-CG2 4.01Å; H111-V116 VanDerWaalsContact O-CB 3.28Å; H111-V116 WeakPolarHBondContact O-CB 3.44Å; H111-V116 WeakPolarHBondContact O-CG2 3.44Å; H111-V116 PolarHBondContact O-N 3.08Å; Q114-V116 HydrophobicContact CB-CG2 4.39Å; Q114-V116 PolarHBondContact O-N 3.12Å; V116-F118 HydrophobicContact CB-CE2 4.21Å; V116-F118 HydrophobicContact CB-CZ 4.29Å; V116-F118 HydrophobicContact CG1-CD1 4.31Å; V116-F118 HydrophobicContact CG1-CD2 4.24Å; V116-F118 HydrophobicContact CG1-CE1 3.93Å; V116-F118 HydrophobicContact CG1-CE2 3.85Å; V116-F118 HydrophobicContact CG1-CG 4.46Å; V116-F118 HydrophobicContact CG1-CZ 3.69Å; V116-F300 HydrophobicContact CG1-CD2 3.83Å; V116-F300 HydrophobicContact CG1-CE2 3.52Å; V116-F300 HydrophobicContact CG1-CZ 4.01Å; V116-F300 HydrophobicContact CG2-CE2 4.14Å; V116-F300 HydrophobicContact CG2-CZ 4.23Å
117H90.4Very high95.9Very high169 Ų16944.8 Ų44.878%0.78223%0.229SC*.  trans-102.3114.8174.5-68.368.6000108.7N115N115-H117 PolarHBondContact O-CE1 3.37Å; N115-H117 PolarHBondContact O-N 3.18Å; N115-H117 PolarHBondContact O-ND1 3.4Å
118F96.9Very high96.2Very high14 Ų1443 Ų436%0.06122%0.219CC..  trans-85.8135.5178.3-62.9-84.9000110.5L108 H111 V116 T122 V123 Y126 L218 F300L108-F118 HydrophobicContact CD2-CE1 4.31Å; L108-F118 HydrophobicContact CD2-CZ 3.98Å; H111-F118 HydrophobicContact CB-CE2 4.33Å; H111-F118 HydrophobicContact CB-CZ 3.8Å; V116-F118 HydrophobicContact CB-CE2 4.21Å; V116-F118 HydrophobicContact CB-CZ 4.29Å; V116-F118 HydrophobicContact CG1-CD1 4.31Å; V116-F118 HydrophobicContact CG1-CD2 4.24Å; V116-F118 HydrophobicContact CG1-CE1 3.93Å; V116-F118 HydrophobicContact CG1-CE2 3.85Å; V116-F118 HydrophobicContact CG1-CG 4.46Å; V116-F118 HydrophobicContact CG1-CZ 3.69Å; F118-T122 HydrophobicContact CD1-CG2 4.03Å; F118-V123 HydrophobicContact CB-CG2 3.68Å; F118-Y126 HydrophobicContact CD1-CE2 4Å; F118-Y126 HydrophobicContact CE1-CE2 4.04Å; F118-L218 HydrophobicContact CD2-CB 4.13Å; F118-L218 HydrophobicContact CD2-CD2 3.81Å; F118-L218 HydrophobicContact CE2-CD2 3.65Å; F118-L218 HydrophobicContact CZ-CD2 4.31Å; F118-F300 HydrophobicContact CD1-CB 4.1Å; F118-F300 HydrophobicContact CD1-CD1 4.46Å; F118-F300 HydrophobicContact CD1-CG 4.2Å; F118-F300 HydrophobicContact CE1-CB 4.1Å; F118-F300 AromaticContact CE1-CD1 3.63Å; F118-F300 HydrophobicContact CE1-CD1 3.63Å; F118-F300 HydrophobicContact CE1-CD2 4.35Å; F118-F300 HydrophobicContact CE1-CE1 4.09Å; F118-F300 AromaticContact CE1-CG 3.75Å; F118-F300 HydrophobicContact CE1-CG 3.75Å; F118-F300 HydrophobicContact CZ-CD1 4.45Å; F118-F300 HydrophobicContact CZ-CE1 4.5Å
119S97.5Very high96.2Very high50 Ų5043 Ų4335%0.3522%0.22SC..  trans-70.2156.917475.90000111.3S121 T122 V123S119-S121 VanDerWaalsContact C-N 3.27Å; S119-S121 PolarHBondContact O-N 3.3Å; S119-S121 PolarHBondContact OG-OG 3.05Å; S119-T122 WeakPolarHBondContact O-CB 3.49Å; S119-T122 PolarHBondContact O-N 3.34Å; S119-T122 VanDerWaalsContact O-N 3.12Å; S119-T122 WeakPolarHBondContact OG-CB 3.44Å; S119-T122 PolarHBondContact OG-N 2.89Å; S119-T122 PolarHBondContact OG-OG1 3.39Å; S119-V123 PolarHBondContact O-N 3.21Å
120E97.9Very high96.4Very high45 Ų4541.5 Ų41.521%0.2121%0.214CC..Hα-helixtrans-58.6-39174.3-76.2-170.4-140.600112.9T122 V123 K124 L219 W251 S252 M255E120-T122 VanDerWaalsContact C-N 3.34Å; E120-T122 PolarHBondContact O-N 2.91Å; E120-V123 PolarHBondContact O-N 2.67Å; E120-K124 VanDerWaalsContact O-CB 3.28Å; E120-K124 WeakPolarHBondContact O-CB 3.25Å; E120-K124 PolarHBondContact O-N 2.64Å; E120-L219 HydrophobicContact CG-CD2 3.98Å; E120-W251 WeakPolarHBondContact OE1-CA 3.06Å; E120-W251 WeakPolarHBondContact OE1-CB 3.49Å; E120-S252 PolarHBondContact OE1-N 3.44Å; E120-S252 WeakPolarHBondContact OE2-CB 3.42Å; E120-S252 PolarHBondContact OE2-N 3.09Å; E120-S252 PolarHBondContact OE2-OG 3.35Å; E120-M255 HydrophobicContact CB-CE 4.04Å; E120-M255 HydrophobicContact CG-CE 4.27Å; E120-M255 HydrophobicContact CG-CG 4.31Å; E120-M255 WeakPolarHBondContact O-CE 3.46Å; E120-M255 WeakPolarHBondContact OE2-CB 3.49Å
121S97.7Very high96.7Very high82 Ų8239.6 Ų39.657%0.57321%0.207SC*.Hα-helixtrans-63.7-38.8175.844.10000112.2S119 L125S119-S121 VanDerWaalsContact C-N 3.27Å; S119-S121 PolarHBondContact O-N 3.3Å; S119-S121 PolarHBondContact OG-OG 3.05Å; S121-L125 PolarHBondContact O-N 3.36Å; S121-L125 VanDerWaalsContact O-N 3.11Å
122T98.4Very high96.9Very high4 Ų440.1 Ų40.13%0.02521%0.21CC..Hα-helixtrans-64.5-48.2175.6-560000110.8F118 S119 E120 K124 L125 Y126 F300F118-T122 HydrophobicContact CD1-CG2 4.03Å; S119-T122 WeakPolarHBondContact O-CB 3.49Å; S119-T122 PolarHBondContact O-N 3.34Å; S119-T122 VanDerWaalsContact O-N 3.12Å; S119-T122 WeakPolarHBondContact OG-CB 3.44Å; S119-T122 PolarHBondContact OG-N 2.89Å; S119-T122 PolarHBondContact OG-OG1 3.39Å; E120-T122 VanDerWaalsContact C-N 3.34Å; E120-T122 PolarHBondContact O-N 2.91Å; T122-K124 PolarHBondContact O-N 3.37Å; T122-L125 PolarHBondContact O-N 3.26Å; T122-Y126 HydrophobicContact CG2-CD1 4.44Å; T122-Y126 HydrophobicContact CG2-CD2 4.3Å; T122-Y126 HydrophobicContact CG2-CE1 3.86Å; T122-Y126 HydrophobicContact CG2-CE2 3.72Å; T122-Y126 VanDerWaalsContact CG2-CZ 3.46Å; T122-Y126 PolarHBondContact O-N 3.44Å; T122-F300 HydrophobicContact CG2-CB 4.04Å
123V98.6Very high97Very high1 Ų139.3 Ų39.31%0.00621%0.205CC..Hα-helixtrans-67.9-36.1-179.6177.40000111.5F118 S119 E120 L125 Y126 I127 A215 L218 L219F118-V123 HydrophobicContact CB-CG2 3.68Å; S119-V123 PolarHBondContact O-N 3.21Å; E120-V123 PolarHBondContact O-N 2.67Å; V123-L125 VanDerWaalsContact C-N 3.33Å; V123-L125 PolarHBondContact O-N 2.97Å; V123-Y126 PolarHBondContact O-N 3.03Å; V123-I127 HydrophobicContact CG1-CD1 4.17Å; V123-I127 HydrophobicContact CG1-CG1 4.48Å; V123-I127 VanDerWaalsContact O-CG1 3.3Å; V123-I127 WeakPolarHBondContact O-CG1 3.2Å; V123-I127 PolarHBondContact O-N 2.94Å; V123-A215 HydrophobicContact CG1-CB 3.73Å; V123-L218 HydrophobicContact CG2-CB 3.87Å; V123-L219 HydrophobicContact CB-CD2 3.88Å; V123-L219 HydrophobicContact CB-CG 4.11Å; V123-L219 HydrophobicContact CG1-CD1 4.24Å; V123-L219 HydrophobicContact CG1-CD2 4.39Å; V123-L219 HydrophobicContact CG1-CG 4.07Å; V123-L219 HydrophobicContact CG2-CD2 3.57Å; V123-L219 HydrophobicContact CG2-CG 3.87Å
124K98.6Very high97.3Very high20 Ų2034 Ų349%0.08718%0.18CC..Hα-helixtrans-55.8-49.2172-176-171.7-176.7175.20110.5E120 T122 I127 C128 M255 Y282 D285E120-K124 VanDerWaalsContact O-CB 3.28Å; E120-K124 WeakPolarHBondContact O-CB 3.25Å; E120-K124 PolarHBondContact O-N 2.64Å; T122-K124 PolarHBondContact O-N 3.37Å; K124-I127 WeakPolarHBondContact O-CB 3.34Å; K124-I127 PolarHBondContact O-N 3.12Å; K124-C128 PolarHBondContact O-N 2.85Å; K124-C128 PolarHBondContact O-SG 2.88Å; K124-C128 VanDerWaalsContact O-SG 3.32Å; K124-M255 HydrophobicContact CB-CE 4.29Å; K124-Y282 HydrophobicContact CB-CE1 4.48Å; K124-Y282 HydrophobicContact CD-CE1 3.91Å; K124-Y282 HydrophobicContact CD-CE2 4.07Å; K124-Y282 WeakPolarHBondContact CE-O 3.27Å; K124-Y282 HydrophobicContact CG-CE1 3.92Å; K124-Y282 PolarHBondContact NZ-O 3.26Å; K124-D285 IonicContact NZ-OD1 3.71Å; K124-D285 PolarHBondContact NZ-OD1 3.08Å; K124-D285 IonicContact NZ-OD2 3.47Å; K124-D285 PolarHBondContact NZ-OD2 3.23Å
125L98.7Very high97.6Very high21 Ų2129.7 Ų29.711%0.1117%0.166CC..Hα-helixtrans-64.2-42.8178.4-176.760.3000112.1S121 T122 V123 I127 C128 E129 V291 L296 P298S121-L125 PolarHBondContact O-N 3.36Å; S121-L125 VanDerWaalsContact O-N 3.11Å; T122-L125 PolarHBondContact O-N 3.26Å; V123-L125 VanDerWaalsContact C-N 3.33Å; V123-L125 PolarHBondContact O-N 2.97Å; L125-I127 VanDerWaalsContact C-N 3.26Å; L125-I127 PolarHBondContact O-N 3.43Å; L125-C128 WeakPolarHBondContact O-CA 3.23Å; L125-C128 WeakPolarHBondContact O-CB 3.4Å; L125-C128 PolarHBondContact O-N 3.28Å; L125-E129 HydrophobicContact CD1-CG 4.33Å; L125-E129 HydrophobicContact CG-CG 4.38Å; L125-E129 WeakPolarHBondContact O-CG 3.47Å; L125-E129 PolarHBondContact O-N 2.96Å; L125-V291 HydrophobicContact CD1-CG1 4.24Å; L125-V291 HydrophobicContact CD1-CG2 4Å; L125-L296 HydrophobicContact CD1-CB 4.23Å; L125-L296 HydrophobicContact CD1-CD1 4.42Å; L125-L296 HydrophobicContact CD2-CB 4.32Å; L125-L296 WeakPolarHBondContact CD2-O 3.26Å; L125-P298 HydrophobicContact CD2-CB 4.1Å; L125-P298 HydrophobicContact CD2-CG 3.75Å
126Y98.8Very high97.9Very high3 Ų325.9 Ų25.91%0.01214%0.143CC..Hα-helixtrans-59.2-37.6175.1-66.6-10.3000112.7L108 F118 T122 V123 L130 L154 G158 V160 L218 P298L108-Y126 HydrophobicContact CD1-CD2 4.41Å; L108-Y126 HydrophobicContact CD1-CE2 4.49Å; L108-Y126 HydrophobicContact CD2-CE2 4.06Å; F118-Y126 HydrophobicContact CD1-CE2 4Å; F118-Y126 HydrophobicContact CE1-CE2 4.04Å; T122-Y126 HydrophobicContact CG2-CD1 4.44Å; T122-Y126 HydrophobicContact CG2-CD2 4.3Å; T122-Y126 HydrophobicContact CG2-CE1 3.86Å; T122-Y126 HydrophobicContact CG2-CE2 3.72Å; T122-Y126 VanDerWaalsContact CG2-CZ 3.46Å; T122-Y126 PolarHBondContact O-N 3.44Å; V123-Y126 PolarHBondContact O-N 3.03Å; Y126-L130 WeakPolarHBondContact O-CB 3.44Å; Y126-L130 VanDerWaalsContact O-CG 3.31Å; Y126-L130 WeakPolarHBondContact O-CG 3.26Å; Y126-L130 PolarHBondContact O-N 3.15Å; Y126-L154 HydrophobicContact CE1-CD2 4.23Å; Y126-G158 VanDerWaalsContact CE1-O 3.3Å; Y126-G158 WeakPolarHBondContact CE1-O 3.47Å; Y126-V160 HydrophobicContact CD1-CB 4.35Å; Y126-V160 HydrophobicContact CD1-CG1 3.51Å; Y126-V160 HydrophobicContact CD1-CG2 3.95Å; Y126-V160 HydrophobicContact CD2-CG1 3.86Å; Y126-V160 HydrophobicContact CE1-CG1 3.72Å; Y126-V160 HydrophobicContact CE2-CG1 4.04Å; Y126-V160 HydrophobicContact CG-CG1 3.6Å; Y126-V160 HydrophobicContact CG-CG2 4.12Å; Y126-L218 HydrophobicContact CD2-CD1 4.13Å; Y126-P298 HydrophobicContact CE1-CB 3.88Å; Y126-P298 HydrophobicContact CE1-CG 4.28Å
127I98.9Very high98.1Very high1 Ų124.3 Ų24.31%0.00513%0.133CC..Hα-helixtrans-62.2-44.8172.7-68.4166.6000110.3V123 K124 L125 A131 L211 A215 L258 L262 L277V123-I127 HydrophobicContact CG1-CD1 4.17Å; V123-I127 HydrophobicContact CG1-CG1 4.48Å; V123-I127 VanDerWaalsContact O-CG1 3.3Å; V123-I127 WeakPolarHBondContact O-CG1 3.2Å; V123-I127 PolarHBondContact O-N 2.94Å; K124-I127 WeakPolarHBondContact O-CB 3.34Å; K124-I127 PolarHBondContact O-N 3.12Å; L125-I127 VanDerWaalsContact C-N 3.26Å; L125-I127 PolarHBondContact O-N 3.43Å; I127-A131 WeakPolarHBondContact O-CB 3.46Å; I127-A131 PolarHBondContact O-N 3.46Å; I127-L211 HydrophobicContact CG1-CD1 4.48Å; I127-L211 HydrophobicContact CG2-CD2 4.29Å; I127-A215 HydrophobicContact CD1-CB 3.71Å; I127-A215 HydrophobicContact CG1-CB 3.88Å; I127-L258 HydrophobicContact CD1-CD2 3.67Å; I127-L258 HydrophobicContact CD1-CG 4.47Å; I127-L258 HydrophobicContact CG2-CD2 4.49Å; I127-L262 HydrophobicContact CD1-CD1 4.49Å; I127-L277 HydrophobicContact CG2-CD1 4.39Å; I127-L277 HydrophobicContact CG2-CD2 4.06Å
128C98.8Very high98.4Very high2 Ų220.8 Ų20.81%0.01411%0.113CC..Hα-helixtrans-61.2-47177.5-63.70000112.4K124 L125 A131 L132 W288 V291K124-C128 PolarHBondContact O-N 2.85Å; K124-C128 PolarHBondContact O-SG 2.88Å; K124-C128 VanDerWaalsContact O-SG 3.32Å; L125-C128 WeakPolarHBondContact O-CA 3.23Å; L125-C128 WeakPolarHBondContact O-CB 3.4Å; L125-C128 PolarHBondContact O-N 3.28Å; C128-A131 PolarHBondContact O-N 3.44Å; C128-L132 WeakPolarHBondContact O-CG 3.16Å; C128-L132 PolarHBondContact O-N 2.92Å; C128-W288 HydrophobicContact CB-CH2 4Å; C128-W288 HydrophobicContact CB-CZ3 3.83Å; C128-V291 HydrophobicContact CB-CG1 4.15Å; C128-V291 HydrophobicContact CB-CG2 4.35Å
129E98.9Very high98.3Very high1 Ų123.7 Ų23.71%0.00514%0.135CC..Hα-helixtrans-62.5-47.4179.9-67.4-176.3168.500111.9F82 L125 L132 A133 H159 V160 V291F82-E129 HydrophobicContact CD1-CB 3.78Å; F82-E129 HydrophobicContact CD1-CG 4.07Å; F82-E129 HydrophobicContact CD2-CB 4.1Å; F82-E129 VanDerWaalsContact CD2-O 3.26Å; F82-E129 WeakPolarHBondContact CD2-O 3.34Å; F82-E129 HydrophobicContact CE1-CB 3.76Å; F82-E129 VanDerWaalsContact CE1-CD 3.49Å; F82-E129 HydrophobicContact CE1-CG 3.5Å; F82-E129 HydrophobicContact CE2-CB 4.11Å; F82-E129 HydrophobicContact CE2-CG 4.1Å; F82-E129 HydrophobicContact CG-CB 3.95Å; F82-E129 HydrophobicContact CZ-CB 3.92Å; F82-E129 HydrophobicContact CZ-CG 3.52Å; L125-E129 HydrophobicContact CD1-CG 4.33Å; L125-E129 HydrophobicContact CG-CG 4.38Å; L125-E129 WeakPolarHBondContact O-CG 3.47Å; L125-E129 PolarHBondContact O-N 2.96Å; E129-L132 PolarHBondContact O-N 2.86Å; E129-A133 PolarHBondContact O-N 3.46Å; E129-H159 IonicContact OE1-CE1 2.73Å; E129-H159 IonicContact OE1-CG 2.71Å; E129-H159 IonicContact OE1-ND1 3.51Å; E129-H159 PolarHBondContact OE1-ND1 2.98Å; E129-H159 WeakPolarHBondContact OE2-CA 3.26Å; E129-H159 IonicContact OE2-ND1 3.2Å; E129-V160 HydrophobicContact CB-CG2 3.69Å; E129-V160 HydrophobicContact CG-CG2 4.5Å; E129-V160 WeakPolarHBondContact OE2-CG2 3.32Å; E129-V160 PolarHBondContact OE2-N 3.08Å; E129-V291 HydrophobicContact CG-CG1 3.78Å
130L98.9Very high98.3Very high7 Ų725.9 Ų25.94%0.03714%0.138CC..Hα-helixtrans-69.2-35.7177.2-66.5171.5000111.6Y126 L132 A133 L134 I152 V160 L162 L211Y126-L130 WeakPolarHBondContact O-CB 3.44Å; Y126-L130 VanDerWaalsContact O-CG 3.31Å; Y126-L130 WeakPolarHBondContact O-CG 3.26Å; Y126-L130 PolarHBondContact O-N 3.15Å; L130-L132 VanDerWaalsContact C-N 3.31Å; L130-L132 PolarHBondContact O-N 2.91Å; L130-A133 CarbonylContact O-C 3.5Å; L130-A133 WeakPolarHBondContact O-CA 3.36Å; L130-A133 WeakPolarHBondContact O-CB 3.37Å; L130-A133 PolarHBondContact O-N 3.22Å; L130-A133 VanDerWaalsContact O-N 3.09Å; L130-L134 WeakPolarHBondContact O-CG 3.49Å; L130-L134 PolarHBondContact O-N 2.77Å; L130-I152 HydrophobicContact CD1-CD1 3.81Å; L130-I152 HydrophobicContact CD1-CG1 4.31Å; L130-I152 HydrophobicContact CD1-CG2 4.32Å; L130-I152 HydrophobicContact CD2-CG2 4.41Å; L130-V160 HydrophobicContact CD1-CG2 4.23Å; L130-V160 HydrophobicContact CD2-CB 4.43Å; L130-V160 HydrophobicContact CD2-CG2 4.09Å; L130-V160 HydrophobicContact CG-CB 4.49Å; L130-V160 HydrophobicContact CG-CG2 3.75Å; L130-L162 HydrophobicContact CD2-CB 4.2Å; L130-L211 HydrophobicContact CB-CD1 3.85Å; L130-L211 HydrophobicContact CB-CD2 4.41Å; L130-L211 HydrophobicContact CD1-CD1 3.57Å; L130-L211 HydrophobicContact CG-CD1 4.36Å
131A98.8Very high98.2Very high0 Ų027 Ų270%014%0.143CC..Hα-helixtrans-61.7-38.3175.600000112.4I127 C128 L134 G135 W208 L274 L277I127-A131 WeakPolarHBondContact O-CB 3.46Å; I127-A131 PolarHBondContact O-N 3.46Å; C128-A131 PolarHBondContact O-N 3.44Å; A131-L134 PolarHBondContact O-N 2.9Å; A131-G135 PolarHBondContact O-N 3.34Å; A131-W208 HydrophobicContact CB-CH2 3.74Å; A131-W208 HydrophobicContact CB-CZ3 3.91Å; A131-L274 HydrophobicContact CB-CD1 4.02Å; A131-L277 HydrophobicContact CB-CD2 3.32Å
132L98.9Very high98.2Very high18 Ų1823.4 Ų23.49%0.09412%0.118CC..Hα-helixtrans-61.2-44.8171.3-73.5166.9000110.9F82 C128 E129 L130 L134 G135 Y136 L274 W288 V291 L292F82-L132 HydrophobicContact CD2-CB 4.09Å; F82-L132 HydrophobicContact CD2-CD1 4.25Å; F82-L132 HydrophobicContact CE2-CB 4.4Å; F82-L132 HydrophobicContact CE2-CD1 3.71Å; C128-L132 WeakPolarHBondContact O-CG 3.16Å; C128-L132 PolarHBondContact O-N 2.92Å; E129-L132 PolarHBondContact O-N 2.86Å; L130-L132 VanDerWaalsContact C-N 3.31Å; L130-L132 PolarHBondContact O-N 2.91Å; L132-L134 PolarHBondContact O-N 3.2Å; L132-G135 PolarHBondContact O-N 2.68Å; L132-Y136 PolarHBondContact O-N 2.88Å; L132-L274 HydrophobicContact CD2-CD1 4.4Å; L132-L274 HydrophobicContact CD2-CD2 3.87Å; L132-W288 HydrophobicContact CD1-CE3 4.29Å; L132-W288 HydrophobicContact CD2-CE3 4.09Å; L132-W288 HydrophobicContact CG-CE3 4.07Å; L132-W288 HydrophobicContact CG-CZ3 4.23Å; L132-V291 HydrophobicContact CD1-CB 4.05Å; L132-V291 HydrophobicContact CD1-CG1 3.58Å; L132-L292 HydrophobicContact CD1-CB 4.14Å; L132-L292 HydrophobicContact CD1-CD1 4.37Å
133A98.8Very high98.2Very high0 Ų023.2 Ų23.20%012%0.116CC..Hα-helixtrans-60.3-43.3174.900000112.4H80 F82 L83 E129 L130 Y136 L137H80-A133 PolarHBondContact CE1-N 3.19Å; F82-A133 HydrophobicContact CB-CB 4.07Å; L83-A133 HydrophobicContact CD2-CB 3.94Å; L83-A133 HydrophobicContact CG-CB 4.47Å; E129-A133 PolarHBondContact O-N 3.46Å; L130-A133 CarbonylContact O-C 3.5Å; L130-A133 WeakPolarHBondContact O-CA 3.36Å; L130-A133 WeakPolarHBondContact O-CB 3.37Å; L130-A133 PolarHBondContact O-N 3.22Å; L130-A133 VanDerWaalsContact O-N 3.09Å; A133-Y136 WeakPolarHBondContact O-CB 3.13Å; A133-Y136 PolarHBondContact O-N 3.34Å; A133-L137 WeakPolarHBondContact O-CG 3.45Å; A133-L137 PolarHBondContact O-N 2.92Å
134L98.7Very high98.1Very high7 Ų723.1 Ų23.14%0.03712%0.116CC..Hα-helixtrans-67.1-38.8177.9-62.3-170.6000112.4L130 A131 L132 Y136 L137 R138 I147 L162 D207 W208 L211L130-L134 WeakPolarHBondContact O-CG 3.49Å; L130-L134 PolarHBondContact O-N 2.77Å; A131-L134 PolarHBondContact O-N 2.9Å; L132-L134 PolarHBondContact O-N 3.2Å; L134-Y136 VanDerWaalsContact C-N 3.32Å; L134-Y136 PolarHBondContact O-N 2.91Å; L134-L137 HydrophobicContact CD2-CD1 4.3Å; L134-L137 PolarHBondContact O-N 3.04Å; L134-R138 WeakPolarHBondContact O-CB 3.4Å; L134-R138 PolarHBondContact O-N 2.86Å; L134-I147 HydrophobicContact CD1-CD1 4.14Å; L134-I147 HydrophobicContact CD2-CD1 3.55Å; L134-I147 HydrophobicContact CG-CD1 4.43Å; L134-L162 HydrophobicContact CD2-CD2 4.27Å; L134-D207 HydrophobicContact CD1-CB 4.11Å; L134-D207 HydrophobicContact CD2-CB 4.08Å; L134-W208 HydrophobicContact CB-CZ2 4.01Å; L134-W208 HydrophobicContact CD1-CD2 4.14Å; L134-W208 HydrophobicContact CD1-CG 4.28Å; L134-L211 HydrophobicContact CD1-CB 4.49Å; L134-L211 HydrophobicContact CD1-CD2 4.15Å
135G98.4Very high98.1Very high20 Ų2023.3 Ų23.321%0.20612%0.116CC..Hα-helixtrans-58-46171.700000111.5A131 L132 R138 S139A131-G135 PolarHBondContact O-N 3.34Å; L132-G135 PolarHBondContact O-N 2.68Å; G135-R138 PolarHBondContact O-N 3.26Å; G135-S139 PolarHBondContact O-N 2.92Å; G135-S139 VanDerWaalsContact O-N 3.13Å
136Y98.6Very high98Very high45 Ų4523 Ų2318%0.17611%0.114CC..Hα-helixtrans-62.2-47.1174.9174.4-102.9000112.6N77 L78 E79 H80 L83 L132 A133 L134 R138 S139 K140N77-Y136 PolarHBondContact O-OH 3.19Å; L78-Y136 HydrophobicContact CB-CE1 4.27Å; L78-Y136 HydrophobicContact CD2-CE1 3.82Å; E79-Y136 PolarHBondContact N-OH 2.73Å; E79-Y136 VanDerWaalsContact N-OH 3.12Å; H80-Y136 HydrophobicContact CB-CD1 3.72Å; H80-Y136 HydrophobicContact CB-CE1 3.98Å; H80-Y136 HydrophobicContact CB-CG 4.13Å; H80-Y136 AromaticContact CD2-CG 3.67Å; L83-Y136 HydrophobicContact CD1-CD1 3.87Å; L83-Y136 HydrophobicContact CD1-CE1 3.93Å; L132-Y136 PolarHBondContact O-N 2.88Å; A133-Y136 WeakPolarHBondContact O-CB 3.13Å; A133-Y136 PolarHBondContact O-N 3.34Å; L134-Y136 VanDerWaalsContact C-N 3.32Å; L134-Y136 PolarHBondContact O-N 2.91Å; Y136-R138 VanDerWaalsContact C-N 3.31Å; Y136-R138 PolarHBondContact O-N 2.78Å; Y136-S139 WeakPolarHBondContact O-CB 3.39Å; Y136-S139 PolarHBondContact O-N 3.12Å; Y136-S139 PolarHBondContact O-OG 2.85Å; Y136-K140 HydrophobicContact CE1-CG 4.23Å; Y136-K140 HydrophobicContact CE2-CG 4.21Å; Y136-K140 PolarHBondContact O-N 3.34Å; Y136-K140 VanDerWaalsContact OH-CE 3.22Å; Y136-K140 WeakPolarHBondContact OH-CE 3.35Å
137L98.1Very high98Very high1 Ų123 Ų231%0.00512%0.115CC..Hα-helixtrans-60.8-39.8178.7-71.1-179.3000112.1L78 L83 A133 L134 S139 K140 H141 I142 H144 L162 F165L78-L137 HydrophobicContact CD1-CD2 3.75Å; L78-L137 HydrophobicContact CD2-CD2 4.03Å; L83-L137 HydrophobicContact CD1-CD2 3.96Å; A133-L137 WeakPolarHBondContact O-CG 3.45Å; A133-L137 PolarHBondContact O-N 2.92Å; L134-L137 HydrophobicContact CD2-CD1 4.3Å; L134-L137 PolarHBondContact O-N 3.04Å; L137-S139 VanDerWaalsContact C-N 3.33Å; L137-S139 PolarHBondContact O-N 2.68Å; L137-K140 CarbonylContact O-C 3.57Å; L137-K140 WeakPolarHBondContact O-CA 3.48Å; L137-K140 PolarHBondContact O-N 3.11Å; L137-H141 PolarHBondContact O-N 3.42Å; L137-H141 VanDerWaalsContact O-N 3.14Å; L137-I142 CarbonylContact C-O 3.59Å; L137-I142 HydrophobicContact CB-CB 4.44Å; L137-I142 HydrophobicContact CD2-CB 4.32Å; L137-I142 HydrophobicContact CD2-CG2 4.09Å; L137-I142 PolarHBondContact O-N 3.19Å; L137-H144 HydrophobicContact CD1-CB 4.36Å; L137-L162 HydrophobicContact CD1-CD2 4.11Å; L137-F165 HydrophobicContact CD1-CE1 4Å; L137-F165 HydrophobicContact CD1-CZ 4.28Å; L137-F165 HydrophobicContact CD2-CE1 3.71Å; L137-F165 HydrophobicContact CD2-CZ 4.02Å
138R96.6Very high97.9Very high94 Ų9424.3 Ų24.336%0.35512%0.12SC..Hα-helixtrans-59.8-42.7173-179.3175.1176.1142.40.1111.7L134 G135 Y136 K140 H141 F204 S272L134-R138 WeakPolarHBondContact O-CB 3.4Å; L134-R138 PolarHBondContact O-N 2.86Å; G135-R138 PolarHBondContact O-N 3.26Å; Y136-R138 VanDerWaalsContact C-N 3.31Å; Y136-R138 PolarHBondContact O-N 2.78Å; R138-K140 PolarHBondContact O-N 2.88Å; R138-K140 VanDerWaalsContact O-N 3.16Å; R138-H141 PolarHBondContact O-N 3.28Å; R138-F204 HydrophobicContact CB-CD1 4.18Å; R138-F204 HydrophobicContact CB-CG 4.41Å; R138-F204 HydrophobicContact CG-CD1 4.14Å; R138-F204 HydrophobicContact CG-CD2 4.1Å; R138-F204 HydrophobicContact CG-CE1 4.37Å; R138-F204 HydrophobicContact CG-CE2 4.32Å; R138-F204 HydrophobicContact CG-CG 4.02Å; R138-F204 HydrophobicContact CG-CZ 4.45Å; R138-S272 PolarHBondContact NH1-O 2.84Å
139S96.4Very high97.9Very high76 Ų7624.2 Ų24.253%0.53112%0.12SC..Hα-helixtrans-61.6-21.7175.684.20000113.4G135 Y136 L137G135-S139 PolarHBondContact O-N 2.92Å; G135-S139 VanDerWaalsContact O-N 3.13Å; Y136-S139 WeakPolarHBondContact O-CB 3.39Å; Y136-S139 PolarHBondContact O-N 3.12Å; Y136-S139 PolarHBondContact O-OG 2.85Å; L137-S139 VanDerWaalsContact C-N 3.33Å; L137-S139 PolarHBondContact O-N 2.68Å
140K96.9Very high97.8Very high96 Ų9627.2 Ų27.242%0.41714%0.136SC..THydrogen-bonded Turntrans-99.89.1175.3-60.3-60.5-173-179.70113.1L78 Y136 L137 R138 I142L78-K140 HydrophobicContact CD2-CB 4.03Å; L78-K140 HydrophobicContact CD2-CG 3.94Å; Y136-K140 HydrophobicContact CE1-CG 4.23Å; Y136-K140 HydrophobicContact CE2-CG 4.21Å; Y136-K140 PolarHBondContact O-N 3.34Å; Y136-K140 VanDerWaalsContact OH-CE 3.22Å; Y136-K140 WeakPolarHBondContact OH-CE 3.35Å; L137-K140 CarbonylContact O-C 3.57Å; L137-K140 WeakPolarHBondContact O-CA 3.48Å; L137-K140 PolarHBondContact O-N 3.11Å; R138-K140 PolarHBondContact O-N 2.88Å; R138-K140 VanDerWaalsContact O-N 3.16Å; K140-I142 HydrophobicContact CB-CD1 3.84Å; K140-I142 HydrophobicContact CB-CG1 4.45Å; K140-I142 PolarHBondContact O-N 2.83Å
141H96.7Very high97.7Very high67 Ų6727.4 Ų27.431%0.3114%0.137SC..THydrogen-bonded Turntrans57.633.6-178.3-54.7-46.9000113.5L137 R138 I170 V171 E173L137-H141 PolarHBondContact O-N 3.42Å; L137-H141 VanDerWaalsContact O-N 3.14Å; R138-H141 PolarHBondContact O-N 3.28Å; H141-I170 HydrophobicContact CB-CG2 4.4Å; H141-I170 CarbonylContact O-C 3.51Å; H141-I170 VanDerWaalsContact O-CA 3.22Å; H141-I170 WeakPolarHBondContact O-CA 3.46Å; H141-V171 WeakPolarHBondContact CB-O 3.35Å; H141-V171 PolarHBondContact O-N 3.04Å; H141-E173 IonicContact CE1-OE1 3.35Å
142I97.1Very high97.7Very high7 Ų727.5 Ų27.54%0.03614%0.137CC..EExtended strand (participates in β ladder)trans-110132.5-178.4-70.3156.1000110.4I74 L78 L137 K140 F165 A168 A169 I170I74-I142 HydrophobicContact CG2-CD1 3.81Å; I74-I142 HydrophobicContact CG2-CG1 4.37Å; I74-I142 HydrophobicContact CG2-CG2 4.45Å; L78-I142 HydrophobicContact CD1-CD1 4.11Å; L78-I142 HydrophobicContact CD2-CD1 3.39Å; L78-I142 HydrophobicContact CG-CD1 4.08Å; L137-I142 CarbonylContact C-O 3.59Å; L137-I142 HydrophobicContact CB-CB 4.44Å; L137-I142 HydrophobicContact CD2-CB 4.32Å; L137-I142 HydrophobicContact CD2-CG2 4.09Å; L137-I142 PolarHBondContact O-N 3.19Å; K140-I142 HydrophobicContact CB-CD1 3.84Å; K140-I142 HydrophobicContact CB-CG1 4.45Å; K140-I142 PolarHBondContact O-N 2.83Å; I142-F165 HydrophobicContact CG2-CD1 4.46Å; I142-F165 HydrophobicContact CG2-CE1 4.35Å; I142-A168 HydrophobicContact CG2-CB 4.26Å; I142-A169 WeakPolarHBondContact CA-O 3.4Å; I142-I170 HydrophobicContact CG1-CG1 4.2Å
143I97.2Very high97.6Very high0 Ų028.3 Ų28.30%014%0.142CC..EExtended strand (participates in β ladder)trans-106.9128.3166.2-48.1177.2000107.5R145 A168 A169 V171 Y202 F204 V206 D207I143-R145 HydrophobicContact CB-CG 4.12Å; I143-R145 HydrophobicContact CG2-CG 3.57Å; I143-A168 CarbonylContact O-C 3.59Å; I143-A168 VanDerWaalsContact O-CA 3.26Å; I143-A168 WeakPolarHBondContact O-CA 3.4Å; I143-A169 PolarHBondContact N-O 3.18Å; I143-A169 PolarHBondContact O-N 3.06Å; I143-V171 HydrophobicContact CD1-CB 3.96Å; I143-V171 HydrophobicContact CD1-CG1 4.44Å; I143-V171 HydrophobicContact CD1-CG2 3.56Å; I143-V171 HydrophobicContact CG1-CB 4.35Å; I143-V171 HydrophobicContact CG1-CG2 4.1Å; I143-Y202 HydrophobicContact CD1-CD2 4.47Å; I143-Y202 HydrophobicContact CD1-CE2 4.43Å; I143-F204 HydrophobicContact CG1-CD1 3.66Å; I143-F204 HydrophobicContact CG1-CE1 3.84Å; I143-F204 HydrophobicContact CG1-CG 4.38Å; I143-V206 HydrophobicContact CG2-CG2 3.58Å; I143-D207 WeakPolarHBondContact CG2-OD2 3.5Å
144H97.9Very high97.5Very high0 Ų028.3 Ų28.30%014%0.142CC..  trans-74.1-45.8-179.1-170-66.5000112.3L137 D146 I147 L162 T163 D164 F165 D207L137-H144 HydrophobicContact CD1-CB 4.36Å; H144-D146 PolarHBondContact ND1-N 2.94Å; H144-D146 PolarHBondContact O-N 3.26Å; H144-I147 HydrophobicContact CB-CD1 4.48Å; H144-I147 HydrophobicContact CB-CG1 4.23Å; H144-L162 HydrophobicContact CB-CD2 4.41Å; H144-L162 WeakPolarHBondContact CD2-CD2 3.29Å; H144-L162 VanDerWaalsContact CD2-CG 3.5Å; H144-L162 WeakPolarHBondContact CD2-CG 3.27Å; H144-T163 PolarHBondContact CE1-O 3Å; H144-T163 PolarHBondContact NE2-O 2.93Å; H144-D164 PolarHBondContact CE1-O 3.28Å; H144-D164 PolarHBondContact NE2-O 3.22Å; H144-F165 AromaticContact CD2-CE1 3.79Å; H144-F165 AromaticContact CD2-CZ 3.96Å; H144-D207 PolarHBondContact N-OD2 2.74Å
145R97.4Very high97.3Very high23 Ų2328.4 Ų28.49%0.08714%0.142CC..  trans67.35.8178.3-51.5-167.6-67.91730.7116.9I143 I167 S179 G182 Y202 D207I143-R145 HydrophobicContact CB-CG 4.12Å; I143-R145 HydrophobicContact CG2-CG 3.57Å; R145-I167 HydrophobicContact CB-CD1 4.31Å; R145-I167 HydrophobicContact CB-CG1 4.49Å; R145-I167 PolarHBondContact NE-O 3.29Å; R145-I167 PolarHBondContact NH2-O 3.49Å; R145-S179 PolarHBondContact NH1-OG 3.45Å; R145-G182 VanDerWaalsContact O-CA 3.28Å; R145-G182 WeakPolarHBondContact O-CA 3.33Å; R145-Y202 WeakPolarHBondContact CD-OH 3.48Å; R145-Y202 HydrophobicContact CG-CE2 4.43Å; R145-Y202 PolarHBondContact NH1-OH 3.39Å; R145-D207 PolarHBondContact N-OD1 2.78Å
146D97.3Very high97Very high14 Ų1431 Ų318%0.07515%0.149CC..  trans-149.240.7-178-152.133.2000113.5H144 K148 N151 I167 T183H144-D146 PolarHBondContact ND1-N 2.94Å; H144-D146 PolarHBondContact O-N 3.26Å; D146-K148 PolarHBondContact O-N 3.14Å; D146-K148 IonicContact OD1-NZ 3.63Å; D146-K148 PolarHBondContact OD1-NZ 3.01Å; D146-K148 IonicContact OD2-NZ 2.68Å; D146-K148 PolarHBondContact OD2-NZ 3.32Å; D146-N151 PolarHBondContact O-ND2 3.09Å; D146-N151 PolarHBondContact OD2-ND2 3.46Å; D146-I167 HydrophobicContact CB-CD1 3.63Å; D146-I167 HydrophobicContact CB-CG1 3.92Å; D146-T183 WeakPolarHBondContact OD1-CB 3.48Å; D146-T183 PolarHBondContact OD1-N 2.92Å; D146-T183 VanDerWaalsContact OD1-N 3.1Å; D146-T183 PolarHBondContact OD1-OG1 2.85Å
147I98.6Very high96.8Very high3 Ų333.1 Ų33.12%0.01516%0.16CC..  trans-73.4118.3174.5-61.9165000108.6L134 H144 I152 L162 D207 S210L134-I147 HydrophobicContact CD1-CD1 4.14Å; L134-I147 HydrophobicContact CD2-CD1 3.55Å; L134-I147 HydrophobicContact CG-CD1 4.43Å; H144-I147 HydrophobicContact CB-CD1 4.48Å; H144-I147 HydrophobicContact CB-CG1 4.23Å; I147-I152 HydrophobicContact CG2-CD1 4.17Å; I147-L162 HydrophobicContact CD1-CD2 4.47Å; I147-L162 HydrophobicContact CG1-CD1 3.95Å; I147-L162 HydrophobicContact CG1-CD2 4.17Å; I147-D207 HydrophobicContact CD1-CB 3.48Å; I147-D207 VanDerWaalsContact CD1-CB 3.48Å; I147-D207 WeakPolarHBondContact CD1-O 3.32Å; I147-S210 WeakPolarHBondContact O-CB 3.44Å
148K98Very high96.7Very high29 Ų2933 Ų3313%0.12616%0.16CC..SBendtrans-161.2162179.766.1-164.2-173-153.20109.1D146 D150 N151 I152 T183 Y186D146-K148 PolarHBondContact O-N 3.14Å; D146-K148 IonicContact OD1-NZ 3.63Å; D146-K148 PolarHBondContact OD1-NZ 3.01Å; D146-K148 IonicContact OD2-NZ 2.68Å; D146-K148 PolarHBondContact OD2-NZ 3.32Å; K148-D150 HydrophobicContact CD-CB 4.33Å; K148-D150 HydrophobicContact CG-CB 4Å; K148-D150 PolarHBondContact O-N 3.41Å; K148-D150 VanDerWaalsContact O-N 3.08Å; K148-N151 WeakPolarHBondContact CE-ND2 3.39Å; K148-N151 HydrophobicContact CG-CB 4.25Å; K148-N151 PolarHBondContact O-N 3.41Å; K148-I152 WeakPolarHBondContact O-CG1 3.38Å; K148-I152 PolarHBondContact O-N 3.33Å; K148-T183 HydrophobicContact CD-CG2 4.35Å; K148-T183 WeakPolarHBondContact CD-OG1 3.49Å; K148-T183 PolarHBondContact NZ-OG1 3.34Å; K148-Y186 HydrophobicContact CB-CD1 3.86Å; K148-Y186 HydrophobicContact CB-CD2 3.75Å; K148-Y186 HydrophobicContact CB-CE1 3.87Å; K148-Y186 HydrophobicContact CB-CE2 3.73Å; K148-Y186 HydrophobicContact CB-CG 3.83Å; K148-Y186 HydrophobicContact CD-CD2 4.46Å
149P97.9Very high96.8Very high0 Ų029 Ų290%015%0.145CC..G310 helixtrans-53.3-32.7-179.1-29.236.6000114.5L108 R109 L112 N151 I152 E217L108-P149 HydrophobicContact CB-CB 3.88Å; L108-P149 PolarHBondContact N-O 3.35Å; L108-P149 VanDerWaalsContact N-O 3.1Å; R109-P149 HydrophobicContact CB-CB 4.05Å; R109-P149 PolarHBondContact N-O 2.87Å; L112-P149 HydrophobicContact CD1-CB 3.89Å; L112-P149 HydrophobicContact CD1-CG 3.81Å; P149-N151 PolarHBondContact O-N 2.9Å; P149-I152 PolarHBondContact O-N 2.97Å; P149-E217 WeakPolarHBondContact CG-OE2 3.39Å
150D95.8Very high96.9Very high64 Ų6425.4 Ų25.434%0.34212%0.12SC..G310 helixtrans-64.5-26.9177.9-47.7-119.2000113.1R109 K148R109-D150 HydrophobicContact CB-CB 4.21Å; R109-D150 WeakPolarHBondContact CG-OD1 3.37Å; R109-D150 IonicContact CZ-OD2 2.72Å; R109-D150 IonicContact NE-OD1 3.19Å; R109-D150 IonicContact NE-OD2 2.83Å; R109-D150 PolarHBondContact NE-OD2 3.29Å; R109-D150 VanDerWaalsContact NE-OD2 3.11Å; R109-D150 IonicContact NH2-OD2 3.69Å; R109-D150 PolarHBondContact NH2-OD2 2.88Å; K148-D150 HydrophobicContact CD-CB 4.33Å; K148-D150 HydrophobicContact CG-CB 4Å; K148-D150 PolarHBondContact O-N 3.41Å; K148-D150 VanDerWaalsContact O-N 3.08Å
151N97.4Very high97Very high12 Ų1221.1 Ų21.16%0.06410%0.101CC..G310 helixtrans-107.513-178-68.2-9.2000112.6D146 K148 P149 T163D146-N151 PolarHBondContact O-ND2 3.09Å; D146-N151 PolarHBondContact OD2-ND2 3.46Å; K148-N151 WeakPolarHBondContact CE-ND2 3.39Å; K148-N151 HydrophobicContact CG-CB 4.25Å; K148-N151 PolarHBondContact O-N 3.41Å; P149-N151 PolarHBondContact O-N 2.9Å; N151-T163 HydrophobicContact CB-CG2 4.49Å; N151-T163 WeakPolarHBondContact O-CG2 3.2Å; N151-T163 PolarHBondContact O-N 3.32Å
152I98.5Very high97.1Very high1 Ų118 Ų181%0.0059%0.087CC..EExtended strand (participates in β ladder)trans-117.6110.7175.5-60.2162.1000107.4D107 L108 L130 I147 K148 P149 V160 H161 L162 A214D107-I152 CarbonylContact C-O 3.6Å; D107-I152 WeakPolarHBondContact CA-O 3.28Å; L108-I152 HydrophobicContact CD1-CB 3.81Å; L108-I152 HydrophobicContact CD1-CD1 4.32Å; L108-I152 HydrophobicContact CD1-CG2 3.42Å; L108-I152 VanDerWaalsContact CD1-CG2 3.42Å; L108-I152 HydrophobicContact CG-CB 4.17Å; L108-I152 HydrophobicContact CG-CG2 3.95Å; L108-I152 PolarHBondContact N-O 2.96Å; L130-I152 HydrophobicContact CD1-CD1 3.81Å; L130-I152 HydrophobicContact CD1-CG1 4.31Å; L130-I152 HydrophobicContact CD1-CG2 4.32Å; L130-I152 HydrophobicContact CD2-CG2 4.41Å; I147-I152 HydrophobicContact CG2-CD1 4.17Å; K148-I152 WeakPolarHBondContact O-CG1 3.38Å; K148-I152 PolarHBondContact O-N 3.33Å; P149-I152 PolarHBondContact O-N 2.97Å; I152-V160 HydrophobicContact CG2-CB 3.63Å; I152-V160 HydrophobicContact CG2-CG1 3.68Å; I152-H161 WeakPolarHBondContact CA-O 3.39Å; I152-L162 HydrophobicContact CG1-CD1 4.31Å; I152-A214 HydrophobicContact CD1-CB 4.32Å
153L97.2Very high97Very high36 Ų3618.9 Ų18.919%0.1889%0.093CC..EExtended strand (participates in β ladder)trans-99.6150.5-177.3-57.1-170.5000111.2V84 L103 G106 D107 V160 H161 T163V84-L153 HydrophobicContact CG2-CD1 4.08Å; L103-L153 HydrophobicContact CB-CB 4.08Å; L103-L153 HydrophobicContact CB-CD1 4.25Å; L103-L153 HydrophobicContact CD1-CB 3.62Å; L103-L153 HydrophobicContact CD1-CD1 4.24Å; L103-L153 HydrophobicContact CG-CB 4.48Å; G106-L153 CarbonylContact O-C 3.48Å; G106-L153 WeakPolarHBondContact O-CA 3.48Å; D107-L153 HydrophobicContact CB-CD2 3.56Å; L153-V160 CarbonylContact O-C 3.59Å; L153-V160 WeakPolarHBondContact O-CA 3.4Å; L153-H161 PolarHBondContact N-O 2.83Å; L153-H161 PolarHBondContact O-N 3.19Å; L153-T163 HydrophobicContact CD1-CG2 3.96Å; L153-T163 HydrophobicContact CD2-CG2 4.27Å; L153-T163 HydrophobicContact CG-CG2 3.77Å
154L97.3Very high96.8Very high0 Ų020.8 Ų20.80%010%0.103CC..EExtended strand (participates in β ladder)trans-102138.9173.8-65.4173.1000110.9L103 G105 G106 L108 Y126 G158 H159 V160 F300 P302L103-L154 WeakPolarHBondContact CB-O 3.47Å; G105-L154 WeakPolarHBondContact CA-O 3.4Å; G105-L154 PolarHBondContact N-O 3.19Å; G106-L154 PolarHBondContact O-N 3.38Å; L108-L154 HydrophobicContact CD2-CD1 3.72Å; L108-L154 HydrophobicContact CD2-CD2 3.99Å; L108-L154 HydrophobicContact CD2-CG 3.86Å; Y126-L154 HydrophobicContact CE1-CD2 4.23Å; L154-G158 VanDerWaalsContact CD2-O 3.23Å; L154-G158 WeakPolarHBondContact CD2-O 3.38Å; L154-H159 WeakPolarHBondContact CA-O 3.3Å; L154-V160 HydrophobicContact CD2-CG1 3.52Å; L154-F300 HydrophobicContact CD1-CD1 3.95Å; L154-F300 HydrophobicContact CD1-CE1 3.74Å; L154-P302 HydrophobicContact CB-CG 3.81Å; L154-P302 HydrophobicContact CD1-CG 3.67Å; L154-P302 HydrophobicContact CG-CG 4.38Å
155D94.6Very high96.7Very high8 Ų821 Ų214%0.04310%0.104CC..  trans-80179164.172.517.5000111.8L103 H157 G158 H159 H161 K294L103-D155 HydrophobicContact CD2-CB 4.01Å; D155-H157 PolarHBondContact O-N 3.38Å; D155-H157 WeakPolarHBondContact OD1-CA 3.22Å; D155-H157 WeakPolarHBondContact OD1-CB 3.27Å; D155-H157 PolarHBondContact OD1-N 2.95Å; D155-G158 PolarHBondContact O-N 3.35Å; D155-G158 VanDerWaalsContact O-N 3.12Å; D155-G158 PolarHBondContact OD1-N 3.23Å; D155-H159 PolarHBondContact N-O 3.5Å; D155-H159 IonicContact OD1-CD2 3.69Å; D155-H159 PolarHBondContact OD1-N 3.07Å; D155-H159 WeakPolarHBondContact OD2-CB 3.45Å; D155-H159 IonicContact OD2-CD2 3.5Å; D155-H159 IonicContact OD2-CG 3.81Å; D155-H161 IonicContact OD2-CE1 3.49Å; D155-H161 PolarHBondContact OD2-CE1 3.13Å; D155-K294 IonicContact OD2-NZ 3.41Å; D155-K294 PolarHBondContact OD2-NZ 3.44Å
156E91.7Very high96.4Very high76 Ų7622.5 Ų22.536%0.35511%0.114SC..THydrogen-bonded Turntrans-69.5-7.2-179.668.1-84.5-172.600115R304E156-R304 PolarHBondContact O-NE 3.23Å; E156-R304 VanDerWaalsContact O-NE 3.08Å; E156-R304 PolarHBondContact O-NH2 2.98Å
157H94.1Very high96.2Very high88 Ų8824.3 Ų24.341%0.40712%0.123SC..THydrogen-bonded Turntrans-103.6-8.4174.7-5599.7000111.8D155 R304D155-H157 PolarHBondContact O-N 3.38Å; D155-H157 WeakPolarHBondContact OD1-CA 3.22Å; D155-H157 WeakPolarHBondContact OD1-CB 3.27Å; D155-H157 PolarHBondContact OD1-N 2.95Å; H157-R304 PolarHBondContact CD2-NH2 3.04Å; H157-R304 VanDerWaalsContact CD2-NH2 3.31Å; H157-R304 PolarHBondContact NE2-NH2 2.56Å
158G96Very high96Very high0 Ų024.2 Ų24.20%012%0.122CC..  trans94.38.9178.600000114.4Y126 L154 D155 P298Y126-G158 VanDerWaalsContact CE1-O 3.3Å; Y126-G158 WeakPolarHBondContact CE1-O 3.47Å; L154-G158 VanDerWaalsContact CD2-O 3.23Å; L154-G158 WeakPolarHBondContact CD2-O 3.38Å; D155-G158 PolarHBondContact O-N 3.35Å; D155-G158 VanDerWaalsContact O-N 3.12Å; D155-G158 PolarHBondContact OD1-N 3.23Å; G158-P298 WeakPolarHBondContact O-CG 3.42Å
159H98.3Very high95.8Very high9 Ų923.2 Ų23.24%0.04212%0.12CC..  trans-76.2141.6176.6-60.2-78.1000111.1F82 E129 L154 D155 H161 K294 L296F82-H159 HydrophobicContact CE1-CB 4.35Å; E129-H159 IonicContact OE1-CE1 2.73Å; E129-H159 IonicContact OE1-CG 2.71Å; E129-H159 IonicContact OE1-ND1 3.51Å; E129-H159 PolarHBondContact OE1-ND1 2.98Å; E129-H159 WeakPolarHBondContact OE2-CA 3.26Å; E129-H159 IonicContact OE2-ND1 3.2Å; L154-H159 WeakPolarHBondContact CA-O 3.3Å; D155-H159 PolarHBondContact N-O 3.5Å; D155-H159 IonicContact OD1-CD2 3.69Å; D155-H159 PolarHBondContact OD1-N 3.07Å; D155-H159 WeakPolarHBondContact OD2-CB 3.45Å; D155-H159 IonicContact OD2-CD2 3.5Å; D155-H159 IonicContact OD2-CG 3.81Å; H159-H161 PolarHBondContact O-CE1 3.25Å; H159-H161 PolarHBondContact O-ND1 2.99Å; H159-K294 HydrophobicContact CB-CD 4.39Å; H159-L296 PolarHBondContact CE1-O 3Å; H159-L296 VanDerWaalsContact CE1-O 3.26Å
160V98.6Very high95.7Very high0 Ų027.6 Ų27.60%014%0.142CC..EExtended strand (participates in β ladder)trans-85.3141-178.5-71.20000112.2F82 L108 Y126 E129 L130 I152 L153 L154F82-V160 WeakPolarHBondContact CD1-O 3.49Å; L108-V160 HydrophobicContact CD1-CG1 4.08Å; Y126-V160 HydrophobicContact CD1-CB 4.35Å; Y126-V160 HydrophobicContact CD1-CG1 3.51Å; Y126-V160 HydrophobicContact CD1-CG2 3.95Å; Y126-V160 HydrophobicContact CD2-CG1 3.86Å; Y126-V160 HydrophobicContact CE1-CG1 3.72Å; Y126-V160 HydrophobicContact CE2-CG1 4.04Å; Y126-V160 HydrophobicContact CG-CG1 3.6Å; Y126-V160 HydrophobicContact CG-CG2 4.12Å; E129-V160 HydrophobicContact CB-CG2 3.69Å; E129-V160 HydrophobicContact CG-CG2 4.5Å; E129-V160 WeakPolarHBondContact OE2-CG2 3.32Å; E129-V160 PolarHBondContact OE2-N 3.08Å; L130-V160 HydrophobicContact CD1-CG2 4.23Å; L130-V160 HydrophobicContact CD2-CB 4.43Å; L130-V160 HydrophobicContact CD2-CG2 4.09Å; L130-V160 HydrophobicContact CG-CB 4.49Å; L130-V160 HydrophobicContact CG-CG2 3.75Å; I152-V160 HydrophobicContact CG2-CB 3.63Å; I152-V160 HydrophobicContact CG2-CG1 3.68Å; L153-V160 CarbonylContact O-C 3.59Å; L153-V160 WeakPolarHBondContact O-CA 3.4Å; L154-V160 HydrophobicContact CD2-CG1 3.52Å
161H98.8Very high95.4Very high6 Ų625 Ų253%0.02813%0.128CC..EExtended strand (participates in β ladder)trans-133.1132.1176.7-58.266.8000109.7P81 F82 V84 L103 I152 L153 D155 H159 K294P81-H161 PolarHBondContact O-CD2 2.96Å; P81-H161 PolarHBondContact O-NE2 2.86Å; P81-H161 VanDerWaalsContact O-NE2 3.11Å; F82-H161 WeakPolarHBondContact O-CA 3.43Å; V84-H161 HydrophobicContact CG2-CB 4.02Å; L103-H161 HydrophobicContact CD1-CB 3.36Å; I152-H161 WeakPolarHBondContact CA-O 3.39Å; L153-H161 PolarHBondContact N-O 2.83Å; L153-H161 PolarHBondContact O-N 3.19Å; D155-H161 IonicContact OD2-CE1 3.49Å; D155-H161 PolarHBondContact OD2-CE1 3.13Å; H159-H161 PolarHBondContact O-CE1 3.25Å; H159-H161 PolarHBondContact O-ND1 2.99Å; H161-K294 PolarHBondContact CE1-NZ 3.34Å; H161-K294 PolarHBondContact NE2-NZ 3.4Å
162L98.6Very high94.9Very high1 Ų131.2 Ų31.21%0.00516%0.155CC..EExtended strand (participates in β ladder)trans-81.1135.3175.2-172.261.7000110.2F82 L83 V84 L130 L134 L137 H144 I147 I152F82-L162 PolarHBondContact O-N 3Å; L83-L162 HydrophobicContact CD2-CB 3.81Å; L83-L162 HydrophobicContact CD2-CD2 4.33Å; L83-L162 HydrophobicContact CD2-CG 4.46Å; V84-L162 PolarHBondContact N-O 3.41Å; L130-L162 HydrophobicContact CD2-CB 4.2Å; L134-L162 HydrophobicContact CD2-CD2 4.27Å; L137-L162 HydrophobicContact CD1-CD2 4.11Å; H144-L162 HydrophobicContact CB-CD2 4.41Å; H144-L162 WeakPolarHBondContact CD2-CD2 3.29Å; H144-L162 VanDerWaalsContact CD2-CG 3.5Å; H144-L162 WeakPolarHBondContact CD2-CG 3.27Å; I147-L162 HydrophobicContact CD1-CD2 4.47Å; I147-L162 HydrophobicContact CG1-CD1 3.95Å; I147-L162 HydrophobicContact CG1-CD2 4.17Å; I152-L162 HydrophobicContact CG1-CD1 4.31Å
163T96.3Very high93.8Very high26 Ų2637.8 Ų37.816%0.1619%0.186CC..  trans-133.8175.5179.5-163.30000111.3H144 N151 L153H144-T163 PolarHBondContact CE1-O 3Å; H144-T163 PolarHBondContact NE2-O 2.93Å; N151-T163 HydrophobicContact CB-CG2 4.49Å; N151-T163 WeakPolarHBondContact O-CG2 3.2Å; N151-T163 PolarHBondContact O-N 3.32Å; L153-T163 HydrophobicContact CD1-CG2 3.96Å; L153-T163 HydrophobicContact CD2-CG2 4.27Å; L153-T163 HydrophobicContact CG-CG2 3.77Å
164D92.7Very high93Very high41 Ų4143.8 Ų43.822%0.21922%0.218CC..  trans65.782.2175.4-1651000115.1H144 N166H144-D164 PolarHBondContact CE1-O 3.28Å; H144-D164 PolarHBondContact NE2-O 3.22Å; D164-N166 VanDerWaalsContact C-N 3.32Å; D164-N166 PolarHBondContact O-N 3.09Å; D164-N166 VanDerWaalsContact OD1-CB 3.27Å; D164-N166 WeakPolarHBondContact OD1-CB 3.33Å; D164-N166 PolarHBondContact OD1-N 3.01Å; D164-N166 PolarHBondContact OD1-ND2 3.26Å; D164-N166 PolarHBondContact OD2-ND2 3.37Å
165F95.1Very high92.5Very high3 Ų348.6 Ų48.61%0.01324%0.243CC..  trans-90.615.1178.1-72.1-97.1000113.3E71 I74 M75 L78 L83 L137 I142 H144 I167 A168E71-F165 HydrophobicContact CG-CB 4.23Å; I74-F165 HydrophobicContact CG2-CB 4.48Å; I74-F165 HydrophobicContact CG2-CD1 4.03Å; I74-F165 HydrophobicContact CG2-CG 4.47Å; M75-F165 HydrophobicContact CE-CD2 4.31Å; M75-F165 HydrophobicContact CG-CB 4.13Å; M75-F165 HydrophobicContact CG-CD2 4.21Å; M75-F165 HydrophobicContact CG-CG 4.32Å; L78-F165 HydrophobicContact CD1-CD1 4.08Å; L78-F165 HydrophobicContact CD1-CE1 3.61Å; L78-F165 HydrophobicContact CD1-CE2 4.39Å; L78-F165 HydrophobicContact CD1-CZ 3.79Å; L83-F165 HydrophobicContact CD1-CZ 4.27Å; L83-F165 HydrophobicContact CD2-CE2 4.47Å; L83-F165 HydrophobicContact CD2-CZ 3.91Å; L137-F165 HydrophobicContact CD1-CE1 4Å; L137-F165 HydrophobicContact CD1-CZ 4.28Å; L137-F165 HydrophobicContact CD2-CE1 3.71Å; L137-F165 HydrophobicContact CD2-CZ 4.02Å; I142-F165 HydrophobicContact CG2-CD1 4.46Å; I142-F165 HydrophobicContact CG2-CE1 4.35Å; H144-F165 AromaticContact CD2-CE1 3.79Å; H144-F165 AromaticContact CD2-CZ 3.96Å; F165-I167 PolarHBondContact O-N 3.35Å; F165-A168 HydrophobicContact CB-CB 4.03Å; F165-A168 HydrophobicContact CD1-CB 3.79Å; F165-A168 HydrophobicContact CG-CB 4.4Å; F165-A168 WeakPolarHBondContact O-CB 3.3Å; F165-A168 PolarHBondContact O-N 2.96Å
166N91Very high92.2Very high56 Ų5653.2 Ų53.230%0.29926%0.263SS..THydrogen-bonded Turntrans-49.5-39.1-176-76.6-34.3000113.2K52 E71 D164K52-N166 PolarHBondContact NZ-OD1 3.29Å; E71-N166 PolarHBondContact OE1-OD1 3.2Å; E71-N166 PolarHBondContact OE2-OD1 3.29Å; D164-N166 VanDerWaalsContact C-N 3.32Å; D164-N166 PolarHBondContact O-N 3.09Å; D164-N166 VanDerWaalsContact OD1-CB 3.27Å; D164-N166 WeakPolarHBondContact OD1-CB 3.33Å; D164-N166 PolarHBondContact OD1-N 3.01Å; D164-N166 PolarHBondContact OD1-ND2 3.26Å; D164-N166 PolarHBondContact OD2-ND2 3.37Å
167I93.3Very high92Very high51 Ų5150.2 Ų50.226%0.26225%0.251SS..THydrogen-bonded Turntrans-111.115.5-178.667166.9000113R145 D146 F165 A181 G182R145-I167 HydrophobicContact CB-CD1 4.31Å; R145-I167 HydrophobicContact CB-CG1 4.49Å; R145-I167 PolarHBondContact NE-O 3.29Å; R145-I167 PolarHBondContact NH2-O 3.49Å; D146-I167 HydrophobicContact CB-CD1 3.63Å; D146-I167 HydrophobicContact CB-CG1 3.92Å; F165-I167 PolarHBondContact O-N 3.35Å; I167-A181 HydrophobicContact CB-CB 4.45Å; I167-A181 HydrophobicContact CD1-CB 4.17Å; I167-G182 VanDerWaalsContact CD1-N 3.29Å
168A95.6Very high91.7Very high1 Ų150.5 Ų50.51%0.00826%0.259CS..  trans-63.1156.1176.100000111.5K70 I74 I142 I143 F165K70-A168 WeakPolarHBondContact CE-O 3.23Å; K70-A168 PolarHBondContact NZ-O 3.48Å; I74-A168 HydrophobicContact CD1-CB 3.84Å; I142-A168 HydrophobicContact CG2-CB 4.26Å; I143-A168 CarbonylContact O-C 3.59Å; I143-A168 VanDerWaalsContact O-CA 3.26Å; I143-A168 WeakPolarHBondContact O-CA 3.4Å; F165-A168 HydrophobicContact CB-CB 4.03Å; F165-A168 HydrophobicContact CD1-CB 3.79Å; F165-A168 HydrophobicContact CG-CB 4.4Å; F165-A168 WeakPolarHBondContact O-CB 3.3Å; F165-A168 PolarHBondContact O-N 2.96Å
169A94Very high91.3Very high9 Ų953.6 Ų53.67%0.07428%0.28CS..EExtended strand (participates in β ladder)trans-133.5138.8178.900000111.2I142 I143 V171I142-A169 WeakPolarHBondContact CA-O 3.4Å; I143-A169 PolarHBondContact N-O 3.18Å; I143-A169 PolarHBondContact O-N 3.06Å; A169-V171 HydrophobicContact CB-CG2 4.22Å
170I93.8Very high90.8Very high91 Ų9155.9 Ų55.947%0.46729%0.293SS..EExtended strand (participates in β ladder)trans-87.8120170-57.4172.1000107.3I74 H141 I142I74-I170 HydrophobicContact CD1-CG1 4.27Å; I74-I170 HydrophobicContact CG1-CD1 4.08Å; I74-I170 HydrophobicContact CG1-CG1 4.09Å; H141-I170 HydrophobicContact CB-CG2 4.4Å; H141-I170 CarbonylContact O-C 3.51Å; H141-I170 VanDerWaalsContact O-CA 3.22Å; H141-I170 WeakPolarHBondContact O-CA 3.46Å; I142-I170 HydrophobicContact CG1-CG1 4.2Å
171V91Very high90.4Very high9 Ų956.9 Ų56.96%0.05530%0.301CS..  trans-131.2110.7-177.5-176.60000108.5H141 I143 A169 L175 A177 F204H141-V171 WeakPolarHBondContact CB-O 3.35Å; H141-V171 PolarHBondContact O-N 3.04Å; I143-V171 HydrophobicContact CD1-CB 3.96Å; I143-V171 HydrophobicContact CD1-CG1 4.44Å; I143-V171 HydrophobicContact CD1-CG2 3.56Å; I143-V171 HydrophobicContact CG1-CB 4.35Å; I143-V171 HydrophobicContact CG1-CG2 4.1Å; A169-V171 HydrophobicContact CB-CG2 4.22Å; V171-L175 HydrophobicContact CG1-CB 4.3Å; V171-L175 WeakPolarHBondContact CG1-O 3.38Å; V171-A177 HydrophobicContact CG2-CB 4.06Å; V171-F204 WeakPolarHBondContact O-CZ 3.31Å
172K86.7Confident90.1Very high144 Ų14457.9 Ų57.963%0.62631%0.312SS*.  trans-64.3154.7174.6-60.7-176177.8-175.40110.2D174 L175K172-D174 VanDerWaalsContact C-N 3.28Å; K172-D174 PolarHBondContact O-N 3.48Å; K172-L175 HydrophobicContact CB-CD1 4.12Å; K172-L175 HydrophobicContact CB-CG 4.29Å; K172-L175 HydrophobicContact CD-CD1 4.43Å; K172-L175 HydrophobicContact CG-CD1 4.46Å; K172-L175 PolarHBondContact O-N 3.4Å
173E75.4Confident89.9Confident139 Ų13960 Ų6065%0.6533%0.325SS*.THydrogen-bonded Turntrans-55.7-38.4-170.6-61.5-169.4159.600114.3H141 L175H141-E173 IonicContact CE1-OE1 3.35Å; E173-L175 VanDerWaalsContact C-N 3.28Å; E173-L175 PolarHBondContact O-N 3.27Å
174D80.1Confident89.8Confident162 Ų16261.5 Ų61.587%0.86633%0.33SS*.THydrogen-bonded Turntrans-83-2.3-179.9-56.8-44.1000114K172K172-D174 VanDerWaalsContact C-N 3.28Å; K172-D174 PolarHBondContact O-N 3.48Å
175L87.4Confident89.9Confident100 Ų10060.1 Ų60.152%0.52432%0.323SS..  trans-108.7153.8-175.6-61.5-178.9000111.3V171 K172 E173V171-L175 HydrophobicContact CG1-CB 4.3Å; V171-L175 WeakPolarHBondContact CG1-O 3.38Å; K172-L175 HydrophobicContact CB-CD1 4.12Å; K172-L175 HydrophobicContact CB-CG 4.29Å; K172-L175 HydrophobicContact CD-CD1 4.43Å; K172-L175 HydrophobicContact CG-CD1 4.46Å; K172-L175 PolarHBondContact O-N 3.4Å; E173-L175 VanDerWaalsContact C-N 3.28Å; E173-L175 PolarHBondContact O-N 3.27Å
176K87.8Confident90Very high106 Ų10660.1 Ų60.146%0.46132%0.323SS..  trans-119.7143172.4-61.4-169.5177.6-1690110.2P200 Y202K176-P200 HydrophobicContact CD-CG 4.39Å; K176-Y202 WeakPolarHBondContact CA-O 3.31Å
177A88.5Confident90.2Very high13 Ų1357.9 Ų57.911%0.10731%0.311CS..BIsolated β-bridgetrans-80144.4168.600000109.9V171 G201 Y202V171-A177 HydrophobicContact CG2-CB 4.06Å; A177-G201 CarbonylContact O-C 3.47Å; A177-G201 VanDerWaalsContact O-CA 3.24Å; A177-G201 WeakPolarHBondContact O-CA 3.49Å; A177-Y202 HydrophobicContact CB-CD1 4.44Å; A177-Y202 HydrophobicContact CB-CD2 4.11Å; A177-Y202 HydrophobicContact CB-CE1 3.94Å; A177-Y202 HydrophobicContact CB-CE2 3.56Å; A177-Y202 VanDerWaalsContact CB-CZ 3.46Å; A177-Y202 PolarHBondContact N-O 2.86Å; A177-Y202 WeakPolarHBondContact O-CD1 3.38Å; A177-Y202 WeakPolarHBondContact O-CE1 3.45Å; A177-Y202 PolarHBondContact O-N 2.67Å
178T86.3Confident90.3Very high93 Ų9355.5 Ų55.557%0.57130%0.298SS*.  trans-121.4-20.9-179.754.80000113I180T178-I180 PolarHBondContact O-N 2.99Å
179S88.1Confident90.2Very high65 Ų6555.5 Ų55.546%0.45530%0.299SS..SBendtrans-68.1130.5178.357.90000111.6R145 A181 Y202R145-S179 PolarHBondContact NH1-OG 3.45Å; S179-A181 PolarHBondContact O-N 3.24Å; S179-Y202 VanDerWaalsContact O-CE1 3.29Å; S179-Y202 WeakPolarHBondContact O-CE1 3.47Å; S179-Y202 PolarHBondContact O-OH 3.29Å
180I87.2Confident90.2Very high58 Ų5855.2 Ų55.230%0.29730%0.296SS..  trans-74.8123.1167.6-68.9-172.4000108.9T178 M187 L191 F192 F195T178-I180 PolarHBondContact O-N 2.99Å; I180-M187 HydrophobicContact CG2-CE 3.89Å; I180-M187 HydrophobicContact CG2-SD 4.1Å; I180-L191 WeakPolarHBondContact CG1-O 3.31Å; I180-F192 HydrophobicContact CD1-CD1 4.43Å; I180-F195 HydrophobicContact CD1-CB 3.17Å; I180-F195 HydrophobicContact CD1-CD1 4.06Å; I180-F195 HydrophobicContact CD1-CD2 3.71Å; I180-F195 HydrophobicContact CD1-CG 3.38Å; I180-F195 HydrophobicContact CG1-CB 3.72Å; I180-F195 HydrophobicContact CG1-CD2 4.06Å; I180-F195 HydrophobicContact CG1-CG 4.11Å
181A90.2Very high90.1Very high20 Ų2051.1 Ų51.117%0.16528%0.275CS..  trans-150.4147170.100000109.5I167 S179 M187I167-A181 HydrophobicContact CB-CB 4.45Å; I167-A181 HydrophobicContact CD1-CB 4.17Å; S179-A181 PolarHBondContact O-N 3.24Å; A181-M187 VanDerWaalsContact C-CE 3.43Å
182G92.9Very high90.1Very high27 Ų2750.8 Ų50.828%0.27827%0.272SS..SBendtrans130.9-174.8-179.100000113.5R145 I167 M187R145-G182 VanDerWaalsContact O-CA 3.28Å; R145-G182 WeakPolarHBondContact O-CA 3.33Å; I167-G182 VanDerWaalsContact CD1-N 3.29Å; G182-M187 VanDerWaalsContact N-CE 3.34Å; G182-M187 WeakPolarHBondContact O-CE 3.39Å
183T93.8Very high90Very high45 Ų4546 Ų4628%0.27625%0.252SS..  trans-97.1110.9175.6-51.30000109.8D146 K148 P185 Y186 M187D146-T183 WeakPolarHBondContact OD1-CB 3.48Å; D146-T183 PolarHBondContact OD1-N 2.92Å; D146-T183 VanDerWaalsContact OD1-N 3.1Å; D146-T183 PolarHBondContact OD1-OG1 2.85Å; K148-T183 HydrophobicContact CD-CG2 4.35Å; K148-T183 WeakPolarHBondContact CD-OG1 3.49Å; K148-T183 PolarHBondContact NZ-OG1 3.34Å; T183-P185 WeakPolarHBondContact O-CD 3.47Å; T183-Y186 HydrophobicContact CG2-CD2 4.05Å; T183-Y186 HydrophobicContact CG2-CE2 4.37Å; T183-Y186 PolarHBondContact O-N 3.46Å; T183-M187 PolarHBondContact O-N 3.16Å
184K94.3Very high90Very high59 Ų5940.1 Ų40.126%0.25723%0.226SC..G310 helixtrans-40.8-46.7-169.6-69.5-176.6179175.70116.4Y186 M187 F192 S229 T231 I236K184-Y186 PolarHBondContact O-N 2.92Å; K184-Y186 VanDerWaalsContact O-N 3.12Å; K184-M187 HydrophobicContact CG-CE 4.44Å; K184-M187 HydrophobicContact CG-SD 4.34Å; K184-M187 PolarHBondContact O-N 3.31Å; K184-M187 VanDerWaalsContact O-N 3.13Å; K184-F192 HydrophobicContact CG-CE1 4.48Å; K184-S229 WeakPolarHBondContact CD-O 3.32Å; K184-S229 VanDerWaalsContact CE-O 3.28Å; K184-S229 WeakPolarHBondContact CE-O 3.43Å; K184-S229 PolarHBondContact NZ-O 3.02Å; K184-T231 PolarHBondContact NZ-O 3.45Å; K184-I236 HydrophobicContact CB-CD1 4.44Å; K184-I236 HydrophobicContact CD-CD1 4.01Å
185P94.9Very high89.7Confident11 Ų1139 Ų397%0.07121%0.214CC..G310 helixtrans-65.5-13.5-178.4-22.137000115.1T183 M227T183-P185 WeakPolarHBondContact O-CD 3.47Å; P185-M227 HydrophobicContact CB-CB 4.32Å; P185-M227 HydrophobicContact CG-CB 4.16Å
186Y96.9Very high89.1Confident4 Ų438.8 Ų38.82%0.01621%0.211CC..G310 helixtrans-107.5-8.1177.5-59.2-87.7000112.7R109 K148 T183 K184 S210 I213 E217R109-Y186 PolarHBondContact NH2-OH 3.14Å; K148-Y186 HydrophobicContact CB-CD1 3.86Å; K148-Y186 HydrophobicContact CB-CD2 3.75Å; K148-Y186 HydrophobicContact CB-CE1 3.87Å; K148-Y186 HydrophobicContact CB-CE2 3.73Å; K148-Y186 HydrophobicContact CB-CG 3.83Å; K148-Y186 HydrophobicContact CD-CD2 4.46Å; T183-Y186 HydrophobicContact CG2-CD2 4.05Å; T183-Y186 HydrophobicContact CG2-CE2 4.37Å; T183-Y186 PolarHBondContact O-N 3.46Å; K184-Y186 PolarHBondContact O-N 2.92Å; K184-Y186 VanDerWaalsContact O-N 3.12Å; Y186-S210 WeakPolarHBondContact O-CB 3.41Å; Y186-S210 PolarHBondContact O-OG 3.32Å; Y186-I213 HydrophobicContact CD1-CB 3.95Å; Y186-I213 HydrophobicContact CD1-CG2 3.4Å; Y186-I213 VanDerWaalsContact CD1-CG2 3.4Å; Y186-I213 HydrophobicContact CE1-CG2 3.64Å; Y186-I213 HydrophobicContact CG-CG2 4.24Å; Y186-E217 WeakPolarHBondContact CE1-OE2 3.26Å; Y186-E217 VanDerWaalsContact CZ-OE2 3.32Å; Y186-E217 VanDerWaalsContact OH-CD 3.3Å; Y186-E217 PolarHBondContact OH-OE1 2.86Å; Y186-E217 PolarHBondContact OH-OE2 3.32Å
187M96.3Very high88.4Confident9 Ų936.9 Ų36.94%0.04422%0.221CC..  trans-71.3140.8-179.6-69-176.6-179.700111I180 A181 G182 T183 K184 L191 F192 W209I180-M187 HydrophobicContact CG2-CE 3.89Å; I180-M187 HydrophobicContact CG2-SD 4.1Å; A181-M187 VanDerWaalsContact C-CE 3.43Å; G182-M187 VanDerWaalsContact N-CE 3.34Å; G182-M187 WeakPolarHBondContact O-CE 3.39Å; T183-M187 PolarHBondContact O-N 3.16Å; K184-M187 HydrophobicContact CG-CE 4.44Å; K184-M187 HydrophobicContact CG-SD 4.34Å; K184-M187 PolarHBondContact O-N 3.31Å; K184-M187 VanDerWaalsContact O-N 3.13Å; M187-L191 HydrophobicContact CB-CD2 4.41Å; M187-L191 HydrophobicContact CG-CD2 4.17Å; M187-L191 HydrophobicContact SD-CD2 4.2Å; M187-F192 HydrophobicContact CB-CE2 3.58Å; M187-F192 HydrophobicContact CB-CZ 3.66Å; M187-F192 HydrophobicContact CG-CZ 4.22Å; M187-F192 HydrophobicContact SD-CE1 3.92Å; M187-F192 HydrophobicContact SD-CE2 4.25Å; M187-F192 HydrophobicContact SD-CZ 3.53Å; M187-F192 VanDerWaalsContact SD-CZ 3.53Å; M187-W209 PolarHBondContact O-NE1 3.22Å; M187-W209 VanDerWaalsContact O-NE1 3.15Å
188A95.6Very high87.6Confident0 Ų040.2 Ų40.20%024%0.243CC..  trans-71.9152.8173.500000112.4E190 L191 V206 W209A188-E190 VanDerWaalsContact C-N 3.25Å; A188-E190 VanDerWaalsContact CB-CD 3.49Å; A188-E190 HydrophobicContact CB-CG 4.44Å; A188-E190 WeakPolarHBondContact CB-OE2 3.37Å; A188-E190 PolarHBondContact O-N 2.9Å; A188-L191 HydrophobicContact CB-CD1 3.76Å; A188-L191 WeakPolarHBondContact O-CD1 3.48Å; A188-L191 PolarHBondContact O-N 3.14Å; A188-V206 HydrophobicContact CB-CB 4.14Å; A188-V206 HydrophobicContact CB-CG1 4.11Å; A188-W209 VanDerWaalsContact CA-CD1 3.43Å; A188-W209 HydrophobicContact CB-CB 3.74Å; A188-W209 HydrophobicContact CB-CD2 4.15Å; A188-W209 HydrophobicContact CB-CG 3.6Å
189P94.1Very high87Confident2 Ų238.6 Ų38.61%0.01323%0.229CC..Hα-helixtrans-54.2-38.9-179-25.833.7000113.8L191 F192 Q193 W209 F240 I265P189-L191 PolarHBondContact O-N 3.43Å; P189-F192 PolarHBondContact O-N 3.04Å; P189-F192 VanDerWaalsContact O-N 3.09Å; P189-Q193 PolarHBondContact O-N 2.79Å; P189-W209 HydrophobicContact CG-CH2 3.74Å; P189-W209 HydrophobicContact CG-CZ2 4.01Å; P189-W209 HydrophobicContact CG-CZ3 4.05Å; P189-F240 HydrophobicContact CB-CD2 3.72Å; P189-F240 HydrophobicContact CB-CE2 3.98Å; P189-F240 HydrophobicContact CB-CG 4.37Å; P189-F240 HydrophobicContact CG-CB 4.49Å; P189-F240 HydrophobicContact CG-CD1 4.33Å; P189-F240 HydrophobicContact CG-CD2 3.68Å; P189-F240 HydrophobicContact CG-CE1 4.48Å; P189-F240 HydrophobicContact CG-CE2 3.83Å; P189-F240 HydrophobicContact CG-CG 3.94Å; P189-F240 HydrophobicContact CG-CZ 4.23Å; P189-I265 HydrophobicContact CB-CG2 4.37Å; P189-I265 HydrophobicContact CG-CG1 4.39Å; P189-I265 HydrophobicContact CG-CG2 4.17Å
190E93.3Very high86.6Confident2 Ų239.9 Ų39.91%0.00924%0.236CC..Hα-helixtrans-64.8-23.1-176.464.3-92-14900113.9A188 F192 Q193 S194 S205 V206 V267 R270A188-E190 VanDerWaalsContact C-N 3.25Å; A188-E190 VanDerWaalsContact CB-CD 3.49Å; A188-E190 HydrophobicContact CB-CG 4.44Å; A188-E190 WeakPolarHBondContact CB-OE2 3.37Å; A188-E190 PolarHBondContact O-N 2.9Å; E190-F192 VanDerWaalsContact C-N 3.29Å; E190-F192 PolarHBondContact O-N 3.39Å; E190-Q193 PolarHBondContact O-N 3.09Å; E190-S194 WeakPolarHBondContact O-CB 3.36Å; E190-S194 PolarHBondContact O-N 3.03Å; E190-S194 PolarHBondContact O-OG 3.49Å; E190-S205 PolarHBondContact OE1-OG 3.01Å; E190-V206 HydrophobicContact CG-CG1 4.01Å; E190-V206 WeakPolarHBondContact OE1-CG1 3.45Å; E190-V267 HydrophobicContact CB-CG2 4.01Å; E190-V267 HydrophobicContact CG-CG2 4.06Å; E190-R270 IonicContact OE1-CZ 3.96Å; E190-R270 IonicContact OE1-NH1 3.67Å; E190-R270 PolarHBondContact OE1-NH1 2.93Å; E190-R270 IonicContact OE1-NH2 2.86Å; E190-R270 IonicContact OE2-CZ 2.74Å; E190-R270 IonicContact OE2-NH1 2.67Å; E190-R270 PolarHBondContact OE2-NH1 3.35Å; E190-R270 IonicContact OE2-NH2 2.95Å; E190-R270 PolarHBondContact OE2-NH2 3.08Å
191L92.5Very high86.6Confident5 Ų537.2 Ų37.23%0.02622%0.223CC..Hα-helixtrans-63.3-38.9173.8-7889.5000111.3I180 M187 A188 P189 F195 Y202 V206I180-L191 WeakPolarHBondContact CG1-O 3.31Å; M187-L191 HydrophobicContact CB-CD2 4.41Å; M187-L191 HydrophobicContact CG-CD2 4.17Å; M187-L191 HydrophobicContact SD-CD2 4.2Å; A188-L191 HydrophobicContact CB-CD1 3.76Å; A188-L191 WeakPolarHBondContact O-CD1 3.48Å; A188-L191 PolarHBondContact O-N 3.14Å; P189-L191 PolarHBondContact O-N 3.43Å; L191-F195 PolarHBondContact O-N 3.4Å; L191-Y202 HydrophobicContact CD2-CE1 4.38Å; L191-Y202 HydrophobicContact CG-CD1 3.99Å; L191-Y202 HydrophobicContact CG-CE1 4.08Å; L191-Y202 HydrophobicContact CG-CG 4.23Å; L191-V206 HydrophobicContact CD1-CB 3.78Å; L191-V206 HydrophobicContact CD1-CG1 3.38Å; L191-V206 HydrophobicContact CG-CG1 4.39Å
192F89.8Confident86.7Confident2 Ų236.4 Ų36.41%0.00922%0.215CC..Hα-helixtrans-77.6-36.7-179.6-55.7-80.2000111.3I180 K184 M187 P189 E190 F195 E196 I236 L237 F240I180-F192 HydrophobicContact CD1-CD1 4.43Å; K184-F192 HydrophobicContact CG-CE1 4.48Å; M187-F192 HydrophobicContact CB-CE2 3.58Å; M187-F192 HydrophobicContact CB-CZ 3.66Å; M187-F192 HydrophobicContact CG-CZ 4.22Å; M187-F192 HydrophobicContact SD-CE1 3.92Å; M187-F192 HydrophobicContact SD-CE2 4.25Å; M187-F192 HydrophobicContact SD-CZ 3.53Å; M187-F192 VanDerWaalsContact SD-CZ 3.53Å; P189-F192 PolarHBondContact O-N 3.04Å; P189-F192 VanDerWaalsContact O-N 3.09Å; E190-F192 VanDerWaalsContact C-N 3.29Å; E190-F192 PolarHBondContact O-N 3.39Å; F192-F195 PolarHBondContact O-N 3.17Å; F192-E196 PolarHBondContact O-N 3.28Å; F192-E196 VanDerWaalsContact O-N 3.17Å; F192-I236 HydrophobicContact CD1-CD1 4.3Å; F192-I236 HydrophobicContact CD1-CG2 4.29Å; F192-I236 HydrophobicContact CD2-CG2 3.72Å; F192-I236 HydrophobicContact CE1-CD1 3.61Å; F192-I236 HydrophobicContact CE1-CG2 4.14Å; F192-I236 HydrophobicContact CE2-CG2 3.55Å; F192-I236 HydrophobicContact CG-CG2 4.09Å; F192-I236 HydrophobicContact CZ-CD1 3.83Å; F192-I236 HydrophobicContact CZ-CG2 3.77Å; F192-L237 HydrophobicContact CB-CD1 4.14Å; F192-L237 HydrophobicContact CB-CD2 3.85Å; F192-L237 HydrophobicContact CB-CG 3.87Å; F192-F240 HydrophobicContact CD2-CE2 4.06Å; F192-F240 HydrophobicContact CE2-CE2 4.06Å; F192-F240 HydrophobicContact CE2-CZ 4.47Å
193Q84.3Confident86.7Confident44 Ų4436.7 Ų36.721%0.20621%0.213CC..Hα-helixtrans-64.1-41.1175.9-63.5172.8-2000111.8P189 E190 F195 E196 G197 S198 H199 L237P189-Q193 PolarHBondContact O-N 2.79Å; E190-Q193 PolarHBondContact O-N 3.09Å; Q193-F195 VanDerWaalsContact C-N 3.31Å; Q193-F195 PolarHBondContact O-N 3.15Å; Q193-E196 PolarHBondContact O-N 3.11Å; Q193-G197 PolarHBondContact O-N 3.22Å; Q193-S198 WeakPolarHBondContact CA-OG 3.39Å; Q193-S198 WeakPolarHBondContact CB-OG 3.47Å; Q193-S198 PolarHBondContact O-N 2.99Å; Q193-S198 PolarHBondContact O-OG 2.9Å; Q193-H199 HydrophobicContact CB-CB 3.73Å; Q193-H199 PolarHBondContact O-N 3.35Å; Q193-L237 HydrophobicContact CG-CD1 4.27Å; Q193-L237 HydrophobicContact CG-CD2 3.66Å
194S75.5Confident86.8Confident15 Ų1535.1 Ų35.111%0.10520%0.202CC..Hα-helixtrans-63.4-36.1176.7-72.90000113.6E190 G197 H199 G201E190-S194 WeakPolarHBondContact O-CB 3.36Å; E190-S194 PolarHBondContact O-N 3.03Å; E190-S194 PolarHBondContact O-OG 3.49Å; S194-G197 PolarHBondContact O-N 2.89Å; S194-G197 VanDerWaalsContact O-N 3.17Å; S194-H199 VanDerWaalsContact CA-O 3.32Å; S194-H199 WeakPolarHBondContact CA-O 3.29Å; S194-H199 PolarHBondContact OG-O 3.23Å; S194-H199 VanDerWaalsContact OG-O 3.11Å; S194-G201 VanDerWaalsContact OG-C 3.31Å; S194-G201 WeakPolarHBondContact OG-CA 3.06Å; S194-G201 PolarHBondContact OG-N 3.16Å; S194-G201 VanDerWaalsContact OG-N 3.14Å
195F74.3Confident86.9Confident138 Ų13832.8 Ų32.861%0.60519%0.194SC*.Hα-helixtrans-69.8-33.9175.8179.4-97.6000113.3I180 L191 F192 Q193 G197I180-F195 HydrophobicContact CD1-CB 3.17Å; I180-F195 HydrophobicContact CD1-CD1 4.06Å; I180-F195 HydrophobicContact CD1-CD2 3.71Å; I180-F195 HydrophobicContact CD1-CG 3.38Å; I180-F195 HydrophobicContact CG1-CB 3.72Å; I180-F195 HydrophobicContact CG1-CD2 4.06Å; I180-F195 HydrophobicContact CG1-CG 4.11Å; L191-F195 PolarHBondContact O-N 3.4Å; F192-F195 PolarHBondContact O-N 3.17Å; Q193-F195 VanDerWaalsContact C-N 3.31Å; Q193-F195 PolarHBondContact O-N 3.15Å; F195-G197 PolarHBondContact O-N 3.49Å
196E74.3Confident87Confident97 Ų9732.4 Ų32.445%0.45319%0.191SC..THydrogen-bonded Turntrans-77.11.1172.7-67.5-174.4175.900112.9F192 Q193 S198 N234 L237F192-E196 PolarHBondContact O-N 3.28Å; F192-E196 VanDerWaalsContact O-N 3.17Å; Q193-E196 PolarHBondContact O-N 3.11Å; E196-S198 PolarHBondContact O-N 3.3Å; E196-N234 PolarHBondContact OE1-N 3.36Å; E196-L237 VanDerWaalsContact OE2-CD1 3.3Å; E196-L237 WeakPolarHBondContact OE2-CD1 3.45Å
197G73.3Confident87.1Confident66 Ų6632.5 Ų32.568%0.6819%0.192SC*.THydrogen-bonded Turntrans73.78.5-179.600000114.3Q193 S194 F195Q193-G197 PolarHBondContact O-N 3.22Å; S194-G197 PolarHBondContact O-N 2.89Å; S194-G197 VanDerWaalsContact O-N 3.17Å; F195-G197 PolarHBondContact O-N 3.49Å
198S71.4Confident87.2Confident82 Ų8232.2 Ų32.257%0.57319%0.19SC*.SBendtrans-88.8-7-179.159.80000113.6Q193 E196Q193-S198 WeakPolarHBondContact CA-OG 3.39Å; Q193-S198 WeakPolarHBondContact CB-OG 3.47Å; Q193-S198 PolarHBondContact O-N 2.99Å; Q193-S198 PolarHBondContact O-OG 2.9Å; E196-S198 PolarHBondContact O-N 3.3Å
199H75.1Confident87.3Confident60 Ų6032.2 Ų32.228%0.27819%0.19SC..SBendtrans-139.9138.9177.3-153.854.5000111.5Q193 S194 G201Q193-H199 HydrophobicContact CB-CB 3.73Å; Q193-H199 PolarHBondContact O-N 3.35Å; S194-H199 VanDerWaalsContact CA-O 3.32Å; S194-H199 WeakPolarHBondContact CA-O 3.29Å; S194-H199 PolarHBondContact OG-O 3.23Å; S194-H199 VanDerWaalsContact OG-O 3.11Å; H199-G201 PolarHBondContact CD2-O 2.86Å; H199-G201 VanDerWaalsContact CD2-O 3.3Å; H199-G201 PolarHBondContact O-N 2.83Å
200P78.9Confident87.5Confident92 Ų9232.3 Ų32.360%0.59719%0.191SC*.SBendtrans-69.2-2.9-170.128.3-36000115K176K176-P200 HydrophobicContact CD-CG 4.39Å
201G87.6Confident87.8Confident1 Ų132.4 Ų32.41%0.0119%0.192CC..  trans138-179.5-179.600000110.9A177 S194 H199A177-G201 CarbonylContact O-C 3.47Å; A177-G201 VanDerWaalsContact O-CA 3.24Å; A177-G201 WeakPolarHBondContact O-CA 3.49Å; S194-G201 VanDerWaalsContact OG-C 3.31Å; S194-G201 WeakPolarHBondContact OG-CA 3.06Å; S194-G201 PolarHBondContact OG-N 3.16Å; S194-G201 VanDerWaalsContact OG-N 3.14Å; H199-G201 PolarHBondContact CD2-O 2.86Å; H199-G201 VanDerWaalsContact CD2-O 3.3Å; H199-G201 PolarHBondContact O-N 2.83Å
202Y91.8Very high88.1Confident4 Ų432.2 Ų32.22%0.01619%0.191CC..BIsolated β-bridgetrans-123166.3175.964.5-91.4000111.9I143 R145 K176 A177 S179 L191 V206I143-Y202 HydrophobicContact CD1-CD2 4.47Å; I143-Y202 HydrophobicContact CD1-CE2 4.43Å; R145-Y202 WeakPolarHBondContact CD-OH 3.48Å; R145-Y202 HydrophobicContact CG-CE2 4.43Å; R145-Y202 PolarHBondContact NH1-OH 3.39Å; K176-Y202 WeakPolarHBondContact CA-O 3.31Å; A177-Y202 HydrophobicContact CB-CD1 4.44Å; A177-Y202 HydrophobicContact CB-CD2 4.11Å; A177-Y202 HydrophobicContact CB-CE1 3.94Å; A177-Y202 HydrophobicContact CB-CE2 3.56Å; A177-Y202 VanDerWaalsContact CB-CZ 3.46Å; A177-Y202 PolarHBondContact N-O 2.86Å; A177-Y202 WeakPolarHBondContact O-CD1 3.38Å; A177-Y202 WeakPolarHBondContact O-CE1 3.45Å; A177-Y202 PolarHBondContact O-N 2.67Å; S179-Y202 VanDerWaalsContact O-CE1 3.29Å; S179-Y202 WeakPolarHBondContact O-CE1 3.47Å; S179-Y202 PolarHBondContact O-OH 3.29Å; L191-Y202 HydrophobicContact CD2-CE1 4.38Å; L191-Y202 HydrophobicContact CG-CD1 3.99Å; L191-Y202 HydrophobicContact CG-CE1 4.08Å; L191-Y202 HydrophobicContact CG-CG 4.23Å; Y202-V206 HydrophobicContact CD2-CB 4.48Å; Y202-V206 HydrophobicContact CD2-CG1 3.66Å; Y202-V206 HydrophobicContact CD2-CG2 4.03Å; Y202-V206 HydrophobicContact CE2-CG2 4.38Å; Y202-V206 HydrophobicContact CG-CG1 3.92Å
203S93.3Very high88.5Confident33 Ų3332.1 Ų32.123%0.23119%0.19CC..  trans-139.2-156-179.5-168.70000109.8S205 V206S203-S205 PolarHBondContact O-N 2.91Å; S203-S205 VanDerWaalsContact O-N 3.09Å; S203-V206 WeakPolarHBondContact O-CG2 3.33Å; S203-V206 PolarHBondContact O-N 3.46Å
204F95.4Very high89.2Confident11 Ų1130.1 Ų30.15%0.04818%0.181CC..THydrogen-bonded Turntrans-59.6-21.6-172.8-52.5-79.2000114.9R138 I143 V171 V206 D207R138-F204 HydrophobicContact CB-CD1 4.18Å; R138-F204 HydrophobicContact CB-CG 4.41Å; R138-F204 HydrophobicContact CG-CD1 4.14Å; R138-F204 HydrophobicContact CG-CD2 4.1Å; R138-F204 HydrophobicContact CG-CE1 4.37Å; R138-F204 HydrophobicContact CG-CE2 4.32Å; R138-F204 HydrophobicContact CG-CG 4.02Å; R138-F204 HydrophobicContact CG-CZ 4.45Å; I143-F204 HydrophobicContact CG1-CD1 3.66Å; I143-F204 HydrophobicContact CG1-CE1 3.84Å; I143-F204 HydrophobicContact CG1-CG 4.38Å; V171-F204 WeakPolarHBondContact O-CZ 3.31Å; F204-V206 PolarHBondContact O-N 2.98Å; F204-V206 VanDerWaalsContact O-N 3.08Å; F204-D207 PolarHBondContact O-N 3.31Å
205S95.9Very high90.3Very high11 Ų1129.6 Ų29.68%0.07718%0.178CC..Hα-helixtrans-58.9-19.9-179.958.10000114.7E190 S203 W208 W209 R270E190-S205 PolarHBondContact OE1-OG 3.01Å; S203-S205 PolarHBondContact O-N 2.91Å; S203-S205 VanDerWaalsContact O-N 3.09Å; S205-W208 PolarHBondContact O-N 2.86Å; S205-W209 PolarHBondContact O-N 2.68Å; S205-R270 PolarHBondContact O-NH1 3.37Å
206V97.4Very high91.5Very high3 Ų323 Ų232%0.01815%0.149CC..Hα-helixtrans-69.1-35.7-179.5-57.50000112I143 A188 E190 L191 Y202 S203 F204 W208 W209 S210I143-V206 HydrophobicContact CG2-CG2 3.58Å; A188-V206 HydrophobicContact CB-CB 4.14Å; A188-V206 HydrophobicContact CB-CG1 4.11Å; E190-V206 HydrophobicContact CG-CG1 4.01Å; E190-V206 WeakPolarHBondContact OE1-CG1 3.45Å; L191-V206 HydrophobicContact CD1-CB 3.78Å; L191-V206 HydrophobicContact CD1-CG1 3.38Å; L191-V206 HydrophobicContact CG-CG1 4.39Å; Y202-V206 HydrophobicContact CD2-CB 4.48Å; Y202-V206 HydrophobicContact CD2-CG1 3.66Å; Y202-V206 HydrophobicContact CD2-CG2 4.03Å; Y202-V206 HydrophobicContact CE2-CG2 4.38Å; Y202-V206 HydrophobicContact CG-CG1 3.92Å; S203-V206 WeakPolarHBondContact O-CG2 3.33Å; S203-V206 PolarHBondContact O-N 3.46Å; F204-V206 PolarHBondContact O-N 2.98Å; F204-V206 VanDerWaalsContact O-N 3.08Å; V206-W208 VanDerWaalsContact C-N 3.33Å; V206-W208 PolarHBondContact O-N 3.47Å; V206-W209 WeakPolarHBondContact O-CB 3.27Å; V206-W209 PolarHBondContact O-N 3.03Å; V206-S210 PolarHBondContact O-N 3.15Å; V206-S210 VanDerWaalsContact O-N 3.08Å; V206-S210 PolarHBondContact O-OG 3.06Å
207D98.5Very high92.6Very high5 Ų518.7 Ų18.73%0.02713%0.129CC..Hα-helixtrans-69.7-34.3179.8-77.7-17.8000111.1L134 I143 H144 R145 I147 F204 S210 L211L134-D207 HydrophobicContact CD1-CB 4.11Å; L134-D207 HydrophobicContact CD2-CB 4.08Å; I143-D207 WeakPolarHBondContact CG2-OD2 3.5Å; H144-D207 PolarHBondContact N-OD2 2.74Å; R145-D207 PolarHBondContact N-OD1 2.78Å; I147-D207 HydrophobicContact CD1-CB 3.48Å; I147-D207 VanDerWaalsContact CD1-CB 3.48Å; I147-D207 WeakPolarHBondContact CD1-O 3.32Å; F204-D207 PolarHBondContact O-N 3.31Å; D207-S210 PolarHBondContact O-N 3.27Å; D207-L211 WeakPolarHBondContact O-CB 3.32Å; D207-L211 PolarHBondContact O-N 3.11Å
208W98.7Very high93.8Very high3 Ų316 Ų161%0.01110%0.098CC..Hα-helixtrans-67.7-36.3174.8-67.785.2000112.7A131 L134 S205 V206 L211 G212 L262 I271 S272 C273 L274 L277A131-W208 HydrophobicContact CB-CH2 3.74Å; A131-W208 HydrophobicContact CB-CZ3 3.91Å; L134-W208 HydrophobicContact CB-CZ2 4.01Å; L134-W208 HydrophobicContact CD1-CD2 4.14Å; L134-W208 HydrophobicContact CD1-CG 4.28Å; S205-W208 PolarHBondContact O-N 2.86Å; V206-W208 VanDerWaalsContact C-N 3.33Å; V206-W208 PolarHBondContact O-N 3.47Å; W208-L211 PolarHBondContact O-N 3.35Å; W208-G212 PolarHBondContact O-N 3Å; W208-L262 HydrophobicContact CB-CD2 4.44Å; W208-L262 HydrophobicContact CE3-CD2 3.94Å; W208-I271 WeakPolarHBondContact CB-O 3.07Å; W208-I271 HydrophobicContact CD2-CG2 4.35Å; W208-I271 HydrophobicContact CE3-CG2 3.65Å; W208-I271 HydrophobicContact CZ3-CG2 3.85Å; W208-S272 PolarHBondContact NE1-O 2.87Å; W208-C273 VanDerWaalsContact CH2-C 3.4Å; W208-C273 WeakPolarHBondContact CH2-O 3.44Å; W208-C273 VanDerWaalsContact CZ2-CA 3.5Å; W208-L274 HydrophobicContact CH2-CB 4.43Å; W208-L277 HydrophobicContact CH2-CB 4.42Å; W208-L277 HydrophobicContact CZ3-CB 4.03Å; W208-L277 HydrophobicContact CZ3-CD2 4.02Å; W208-L277 HydrophobicContact CZ3-CG 4.46Å
209W98.6Very high95Very high0 Ų013.1 Ų13.10%08%0.076CC..Hα-helixtrans-63-48.7170.5171.6-82.3000111.3M187 A188 P189 S205 V206 L211 G212 I213 Y225 F240 L263 I265M187-W209 PolarHBondContact O-NE1 3.22Å; M187-W209 VanDerWaalsContact O-NE1 3.15Å; A188-W209 VanDerWaalsContact CA-CD1 3.43Å; A188-W209 HydrophobicContact CB-CB 3.74Å; A188-W209 HydrophobicContact CB-CD2 4.15Å; A188-W209 HydrophobicContact CB-CG 3.6Å; P189-W209 HydrophobicContact CG-CH2 3.74Å; P189-W209 HydrophobicContact CG-CZ2 4.01Å; P189-W209 HydrophobicContact CG-CZ3 4.05Å; S205-W209 PolarHBondContact O-N 2.68Å; V206-W209 WeakPolarHBondContact O-CB 3.27Å; V206-W209 PolarHBondContact O-N 3.03Å; W209-L211 VanDerWaalsContact C-N 3.27Å; W209-L211 PolarHBondContact O-N 3.07Å; W209-G212 CarbonylContact O-C 3.54Å; W209-G212 WeakPolarHBondContact O-CA 3.34Å; W209-G212 PolarHBondContact O-N 2.98Å; W209-I213 HydrophobicContact CZ2-CD1 4.26Å; W209-I213 PolarHBondContact O-N 3.41Å; W209-Y225 HydrophobicContact CH2-CE2 4.17Å; W209-Y225 AromaticContact CZ2-CE2 3.92Å; W209-Y225 HydrophobicContact CZ2-CE2 3.92Å; W209-F240 HydrophobicContact CH2-CD1 4.3Å; W209-F240 HydrophobicContact CH2-CE1 4.26Å; W209-F240 HydrophobicContact CZ2-CD1 4.07Å; W209-F240 AromaticContact CZ2-CE1 3.59Å; W209-F240 HydrophobicContact CZ2-CE1 3.59Å; W209-F240 HydrophobicContact CZ2-CZ 4.1Å; W209-L263 HydrophobicContact CD2-CD2 4.18Å; W209-L263 HydrophobicContact CE3-CD2 4.34Å; W209-L263 VanDerWaalsContact CZ3-C 3.43Å; W209-L263 HydrophobicContact CZ3-CB 4.4Å; W209-L263 WeakPolarHBondContact CZ3-O 3.22Å; W209-I265 HydrophobicContact CH2-CG1 4.06Å; W209-I265 HydrophobicContact CZ3-CG1 4.16Å
210S98.6Very high96Very high5 Ų514 Ų144%0.0358%0.078CC..Hα-helixtrans-60.3-37.9179-58.80000112I147 Y186 V206 D207 G212 I213 A214I147-S210 WeakPolarHBondContact O-CB 3.44Å; Y186-S210 WeakPolarHBondContact O-CB 3.41Å; Y186-S210 PolarHBondContact O-OG 3.32Å; V206-S210 PolarHBondContact O-N 3.15Å; V206-S210 VanDerWaalsContact O-N 3.08Å; V206-S210 PolarHBondContact O-OG 3.06Å; D207-S210 PolarHBondContact O-N 3.27Å; S210-G212 VanDerWaalsContact C-N 3.34Å; S210-I213 PolarHBondContact O-N 3.01Å; S210-A214 WeakPolarHBondContact O-CB 3.45Å; S210-A214 PolarHBondContact O-N 2.94Å
211L98.8Very high96.8Very high4 Ų412.2 Ų12.22%0.0218%0.076CC..Hα-helixtrans-58.8-43.7170176.959.1000111.9I127 L130 L134 D207 W208 W209 I213 A214 A215I127-L211 HydrophobicContact CG1-CD1 4.48Å; I127-L211 HydrophobicContact CG2-CD2 4.29Å; L130-L211 HydrophobicContact CB-CD1 3.85Å; L130-L211 HydrophobicContact CB-CD2 4.41Å; L130-L211 HydrophobicContact CD1-CD1 3.57Å; L130-L211 HydrophobicContact CG-CD1 4.36Å; L134-L211 HydrophobicContact CD1-CB 4.49Å; L134-L211 HydrophobicContact CD1-CD2 4.15Å; D207-L211 WeakPolarHBondContact O-CB 3.32Å; D207-L211 PolarHBondContact O-N 3.11Å; W208-L211 PolarHBondContact O-N 3.35Å; W209-L211 VanDerWaalsContact C-N 3.27Å; W209-L211 PolarHBondContact O-N 3.07Å; L211-I213 PolarHBondContact O-N 2.82Å; L211-A214 PolarHBondContact O-N 2.95Å; L211-A215 WeakPolarHBondContact O-CB 3.45Å; L211-A215 PolarHBondContact O-N 3.38Å
212G98.7Very high97.2Very high0 Ų016.8 Ų16.80%010%0.097CC..Hα-helixtrans-60.4-41.8173.900000113.3W208 W209 S210 Y216W208-G212 PolarHBondContact O-N 3Å; W209-G212 CarbonylContact O-C 3.54Å; W209-G212 WeakPolarHBondContact O-CA 3.34Å; W209-G212 PolarHBondContact O-N 2.98Å; S210-G212 VanDerWaalsContact C-N 3.34Å; G212-Y216 WeakPolarHBondContact O-CB 3.48Å; G212-Y216 PolarHBondContact O-N 3.23Å
213I98.5Very high97.4Very high1 Ų120.4 Ų20.41%0.00511%0.11CC..Hα-helixtrans-64.6-45.8177.2-61.8-68.3000110.1Y186 W209 S210 L211 Y216 E217 R223 P224 Y225 L263Y186-I213 HydrophobicContact CD1-CB 3.95Å; Y186-I213 HydrophobicContact CD1-CG2 3.4Å; Y186-I213 VanDerWaalsContact CD1-CG2 3.4Å; Y186-I213 HydrophobicContact CE1-CG2 3.64Å; Y186-I213 HydrophobicContact CG-CG2 4.24Å; W209-I213 HydrophobicContact CZ2-CD1 4.26Å; W209-I213 PolarHBondContact O-N 3.41Å; S210-I213 PolarHBondContact O-N 3.01Å; L211-I213 PolarHBondContact O-N 2.82Å; I213-Y216 PolarHBondContact O-N 2.93Å; I213-E217 WeakPolarHBondContact O-CB 3.35Å; I213-E217 PolarHBondContact O-N 3.33Å; I213-R223 HydrophobicContact CG2-CG 4.35Å; I213-P224 HydrophobicContact CD1-CG 3.48Å; I213-P224 VanDerWaalsContact CD1-CG 3.48Å; I213-Y225 HydrophobicContact CD1-CD2 4.06Å; I213-Y225 HydrophobicContact CD1-CE2 4.27Å; I213-L263 HydrophobicContact CD1-CD2 3.48Å; I213-L263 VanDerWaalsContact CD1-CD2 3.48Å; I213-L263 HydrophobicContact CG1-CD2 3.76Å
214A98.6Very high97.5Very high2 Ų219.3 Ų19.32%0.01710%0.102CC..Hα-helixtrans-62.8-4817900000111.5I152 S210 L211 Y216 E217 L218I152-A214 HydrophobicContact CD1-CB 4.32Å; S210-A214 WeakPolarHBondContact O-CB 3.45Å; S210-A214 PolarHBondContact O-N 2.94Å; L211-A214 PolarHBondContact O-N 2.95Å; A214-Y216 PolarHBondContact O-N 3.27Å; A214-E217 PolarHBondContact O-N 3.11Å; A214-E217 VanDerWaalsContact O-N 3.16Å; A214-L218 VanDerWaalsContact O-CG 3.27Å; A214-L218 WeakPolarHBondContact O-CG 3.37Å; A214-L218 PolarHBondContact O-N 3.1Å
215A98.7Very high97.4Very high3 Ų319 Ų193%0.02510%0.101CC..Hα-helixtrans-60.7-42.5177.300000112.9V123 I127 L211 E217 L218 L219 L259V123-A215 HydrophobicContact CG1-CB 3.73Å; I127-A215 HydrophobicContact CD1-CB 3.71Å; I127-A215 HydrophobicContact CG1-CB 3.88Å; L211-A215 WeakPolarHBondContact O-CB 3.45Å; L211-A215 PolarHBondContact O-N 3.38Å; A215-E217 VanDerWaalsContact C-N 3.32Å; A215-E217 PolarHBondContact O-N 3.3Å; A215-L218 PolarHBondContact O-N 3.25Å; A215-L219 PolarHBondContact O-N 3.47Å; A215-L259 HydrophobicContact CB-CD2 3.86Å
216Y98.6Very high97Very high0 Ų024.2 Ų24.20%013%0.132CC..Hα-helixtrans-60.1-44.5174.2-178.5-78.1000111.5G212 I213 A214 L219 R220 Q222 P224 P245 T246 Y247 W251 L259 L263G212-Y216 WeakPolarHBondContact O-CB 3.48Å; G212-Y216 PolarHBondContact O-N 3.23Å; I213-Y216 PolarHBondContact O-N 2.93Å; A214-Y216 PolarHBondContact O-N 3.27Å; Y216-L219 PolarHBondContact O-N 2.66Å; Y216-R220 HydrophobicContact CD1-CB 4.32Å; Y216-R220 HydrophobicContact CE1-CB 4.04Å; Y216-R220 HydrophobicContact CE1-CG 4.33Å; Y216-R220 WeakPolarHBondContact O-CB 3.47Å; Y216-R220 PolarHBondContact O-N 3.33Å; Y216-R220 WeakPolarHBondContact OH-CD 3.46Å; Y216-R220 VanDerWaalsContact OH-CZ 3.32Å; Y216-R220 PolarHBondContact OH-NE 3.35Å; Y216-R220 PolarHBondContact OH-NH1 3.13Å; Y216-Q222 WeakPolarHBondContact CD1-O 3.4Å; Y216-Q222 WeakPolarHBondContact CE1-O 3.41Å; Y216-P224 HydrophobicContact CD1-CB 3.77Å; Y216-P224 HydrophobicContact CD1-CG 3.89Å; Y216-P224 HydrophobicContact CD2-CB 4.2Å; Y216-P224 VanDerWaalsContact CE1-CA 3.4Å; Y216-P224 HydrophobicContact CE1-CB 3.6Å; Y216-P224 HydrophobicContact CE1-CG 4.22Å; Y216-P224 HydrophobicContact CE2-CB 4.08Å; Y216-P224 HydrophobicContact CG-CB 4.05Å; Y216-P224 HydrophobicContact CG-CG 4.08Å; Y216-P245 HydrophobicContact CE2-CB 4.37Å; Y216-T246 WeakPolarHBondContact CE2-O 3.38Å; Y216-T246 PolarHBondContact OH-O 2.88Å; Y216-Y247 HydrophobicContact CD2-CE1 4.09Å; Y216-Y247 HydrophobicContact CE2-CD1 4.26Å; Y216-Y247 HydrophobicContact CE2-CE1 4.08Å; Y216-W251 AromaticContact CD2-CH2 3.87Å; Y216-W251 HydrophobicContact CD2-CH2 3.87Å; Y216-W251 AromaticContact CD2-CZ3 3.88Å; Y216-W251 HydrophobicContact CD2-CZ3 3.88Å; Y216-W251 AromaticContact CE2-CH2 3.83Å; Y216-W251 HydrophobicContact CE2-CH2 3.83Å; Y216-W251 AromaticContact CE2-CZ3 3.87Å; Y216-W251 HydrophobicContact CE2-CZ3 3.87Å; Y216-W251 HydrophobicContact CG-CH2 4.34Å; Y216-L259 HydrophobicContact CD2-CD1 4.27Å; Y216-L263 HydrophobicContact CD2-CD1 4.46Å
217E97.9Very high96.5Very high7 Ų724.3 Ų24.33%0.03313%0.132CC..Hα-helixtrans-65-38.3179.2-173.9177.6-165.300112.3R109 L112 P149 Y186 I213 A214 A215 L219 R220 G221 R223R109-E217 IonicContact CZ-OE1 3.52Å; R109-E217 IonicContact NH1-OE1 3.14Å; R109-E217 PolarHBondContact NH1-OE1 2.83Å; R109-E217 IonicContact NH2-OE1 3.87Å; R109-E217 PolarHBondContact NH2-OE1 3.29Å; R109-E217 IonicContact NH2-OE2 3.34Å; L112-E217 HydrophobicContact CD1-CG 3.91Å; P149-E217 WeakPolarHBondContact CG-OE2 3.39Å; Y186-E217 WeakPolarHBondContact CE1-OE2 3.26Å; Y186-E217 VanDerWaalsContact CZ-OE2 3.32Å; Y186-E217 VanDerWaalsContact OH-CD 3.3Å; Y186-E217 PolarHBondContact OH-OE1 2.86Å; Y186-E217 PolarHBondContact OH-OE2 3.32Å; I213-E217 WeakPolarHBondContact O-CB 3.35Å; I213-E217 PolarHBondContact O-N 3.33Å; A214-E217 PolarHBondContact O-N 3.11Å; A214-E217 VanDerWaalsContact O-N 3.16Å; A215-E217 VanDerWaalsContact C-N 3.32Å; A215-E217 PolarHBondContact O-N 3.3Å; E217-L219 VanDerWaalsContact C-N 3.32Å; E217-L219 PolarHBondContact O-N 3.14Å; E217-R220 PolarHBondContact O-N 3.24Å; E217-G221 VanDerWaalsContact O-CA 3.23Å; E217-G221 WeakPolarHBondContact O-CA 3.42Å; E217-G221 PolarHBondContact O-N 2.91Å; E217-R223 HydrophobicContact CB-CG 4.31Å; E217-R223 HydrophobicContact CG-CG 4.1Å
218L98.2Very high95.8Very high8 Ų833 Ų334%0.04217%0.165CC..Hα-helixtrans-62.3-37.9175.7-68.2169.4000112.7L108 L112 F118 V123 Y126 A214 A215L108-L218 HydrophobicContact CB-CD2 4.16Å; L108-L218 HydrophobicContact CD1-CD1 3.83Å; L108-L218 HydrophobicContact CD1-CD2 4Å; L108-L218 HydrophobicContact CD2-CD2 4.38Å; L108-L218 HydrophobicContact CG-CD2 4.44Å; L112-L218 HydrophobicContact CD1-CD2 4.16Å; L112-L218 HydrophobicContact CD2-CD2 4.33Å; L112-L218 HydrophobicContact CG-CD2 4.17Å; F118-L218 HydrophobicContact CD2-CB 4.13Å; F118-L218 HydrophobicContact CD2-CD2 3.81Å; F118-L218 HydrophobicContact CE2-CD2 3.65Å; F118-L218 HydrophobicContact CZ-CD2 4.31Å; V123-L218 HydrophobicContact CG2-CB 3.87Å; Y126-L218 HydrophobicContact CD2-CD1 4.13Å; A214-L218 VanDerWaalsContact O-CG 3.27Å; A214-L218 WeakPolarHBondContact O-CG 3.37Å; A214-L218 PolarHBondContact O-N 3.1Å; A215-L218 PolarHBondContact O-N 3.25Å
219L97.8Very high94.8Very high22 Ų2237.7 Ų37.712%0.11520%0.198CC..Hα-helixtrans-78.1-36.4178.4-68.2171.5000113E120 V123 A215 Y216 E217 W251 M255 L259E120-L219 HydrophobicContact CG-CD2 3.98Å; V123-L219 HydrophobicContact CB-CD2 3.88Å; V123-L219 HydrophobicContact CB-CG 4.11Å; V123-L219 HydrophobicContact CG1-CD1 4.24Å; V123-L219 HydrophobicContact CG1-CD2 4.39Å; V123-L219 HydrophobicContact CG1-CG 4.07Å; V123-L219 HydrophobicContact CG2-CD2 3.57Å; V123-L219 HydrophobicContact CG2-CG 3.87Å; A215-L219 PolarHBondContact O-N 3.47Å; Y216-L219 PolarHBondContact O-N 2.66Å; E217-L219 VanDerWaalsContact C-N 3.32Å; E217-L219 PolarHBondContact O-N 3.14Å; L219-W251 HydrophobicContact CB-CH2 3.91Å; L219-W251 HydrophobicContact CB-CZ2 3.43Å; L219-W251 VanDerWaalsContact CB-CZ2 3.43Å; L219-W251 HydrophobicContact CD1-CH2 4.48Å; L219-W251 HydrophobicContact CD1-CZ2 4.47Å; L219-M255 HydrophobicContact CD1-CE 4.17Å; L219-M255 HydrophobicContact CD1-CG 3.69Å; L219-M255 HydrophobicContact CD1-SD 3.77Å; L219-L259 HydrophobicContact CD1-CD1 4.07Å
220R96.4Very high94.2Very high80 Ų8043.4 Ų43.430%0.30223%0.229SC..Hα-helixtrans-98.6-16.8-172.2-157.8177.8174.3-141.3-4.2113.9Y216 E217 Q222 W251Y216-R220 HydrophobicContact CD1-CB 4.32Å; Y216-R220 HydrophobicContact CE1-CB 4.04Å; Y216-R220 HydrophobicContact CE1-CG 4.33Å; Y216-R220 WeakPolarHBondContact O-CB 3.47Å; Y216-R220 PolarHBondContact O-N 3.33Å; Y216-R220 WeakPolarHBondContact OH-CD 3.46Å; Y216-R220 VanDerWaalsContact OH-CZ 3.32Å; Y216-R220 PolarHBondContact OH-NE 3.35Å; Y216-R220 PolarHBondContact OH-NH1 3.13Å; E217-R220 PolarHBondContact O-N 3.24Å; R220-Q222 HydrophobicContact CB-CG 4.36Å; R220-Q222 HydrophobicContact CG-CG 3.89Å; R220-Q222 PolarHBondContact O-N 2.97Å; R220-W251 HydrophobicContact CB-CH2 4.03Å; R220-W251 HydrophobicContact CB-CZ2 3.84Å; R220-W251 HydrophobicContact CG-CZ2 4.3Å
221G95.6Very high93.8Very high54 Ų5444 Ų4456%0.55723%0.232SC*.SBendtrans730.2-16800000114.2E217E217-G221 VanDerWaalsContact O-CA 3.23Å; E217-G221 WeakPolarHBondContact O-CA 3.42Å; E217-G221 PolarHBondContact O-N 2.91Å
222Q94.8Very high93.4Very high96 Ų9649.6 Ų49.645%0.44926%0.258SS..SBendtrans-149.8150.5179.461.4-178.7-20.900111.3Y216 R220Y216-Q222 WeakPolarHBondContact CD1-O 3.4Å; Y216-Q222 WeakPolarHBondContact CE1-O 3.41Å; R220-Q222 HydrophobicContact CB-CG 4.36Å; R220-Q222 HydrophobicContact CG-CG 3.89Å; R220-Q222 PolarHBondContact O-N 2.97Å
223R95.6Very high92.9Very high80 Ų8050.8 Ų50.830%0.30227%0.267SS..  trans-66.5153.8179.3-67.7169.9-66.8-156-1.1112.1I213 E217 Y225I213-R223 HydrophobicContact CG2-CG 4.35Å; E217-R223 HydrophobicContact CB-CG 4.31Å; E217-R223 HydrophobicContact CG-CG 4.1Å; R223-Y225 VanDerWaalsContact C-N 3.29Å; R223-Y225 PolarHBondContact O-N 3.49Å
224P95.6Very high92.4Very high10 Ų1054.1 Ų54.17%0.06528%0.284CS..SBendtrans-70.8-27.3178.625.9-29000112.7I213 Y216 P245 L263I213-P224 HydrophobicContact CD1-CG 3.48Å; I213-P224 VanDerWaalsContact CD1-CG 3.48Å; Y216-P224 HydrophobicContact CD1-CB 3.77Å; Y216-P224 HydrophobicContact CD1-CG 3.89Å; Y216-P224 HydrophobicContact CD2-CB 4.2Å; Y216-P224 VanDerWaalsContact CE1-CA 3.4Å; Y216-P224 HydrophobicContact CE1-CB 3.6Å; Y216-P224 HydrophobicContact CE1-CG 4.22Å; Y216-P224 HydrophobicContact CE2-CB 4.08Å; Y216-P224 HydrophobicContact CG-CB 4.05Å; Y216-P224 HydrophobicContact CG-CG 4.08Å; P224-P245 HydrophobicContact CB-CB 3.83Å; P224-P245 HydrophobicContact CB-CG 4.04Å; P224-L263 HydrophobicContact CG-CD1 4.17Å
225Y94.3Very high92.1Very high5 Ų559 Ų592%0.0231%0.307CS..SBendtrans-118.8131.7176.6-55.9-80.6000110.5W209 I213 R223 M227 M239 F240 V243 P245W209-Y225 HydrophobicContact CH2-CE2 4.17Å; W209-Y225 AromaticContact CZ2-CE2 3.92Å; W209-Y225 HydrophobicContact CZ2-CE2 3.92Å; I213-Y225 HydrophobicContact CD1-CD2 4.06Å; I213-Y225 HydrophobicContact CD1-CE2 4.27Å; R223-Y225 VanDerWaalsContact C-N 3.29Å; R223-Y225 PolarHBondContact O-N 3.49Å; Y225-M227 HydrophobicContact CG-CE 4.21Å; Y225-M227 PolarHBondContact O-N 3.26Å; Y225-M239 HydrophobicContact CD1-CG 4.24Å; Y225-M239 HydrophobicContact CD1-SD 4.4Å; Y225-F240 HydrophobicContact CD1-CD1 4.09Å; Y225-F240 HydrophobicContact CD1-CE1 4.39Å; Y225-F240 HydrophobicContact CD2-CD1 4.17Å; Y225-F240 AromaticContact CD2-CE1 3.83Å; Y225-F240 HydrophobicContact CD2-CE1 3.83Å; Y225-F240 AromaticContact CE1-CD1 3.85Å; Y225-F240 HydrophobicContact CE1-CD1 3.85Å; Y225-F240 HydrophobicContact CE1-CE1 4.46Å; Y225-F240 AromaticContact CE2-CD1 3.96Å; Y225-F240 HydrophobicContact CE2-CD1 3.96Å; Y225-F240 AromaticContact CE2-CE1 3.93Å; Y225-F240 HydrophobicContact CE2-CE1 3.93Å; Y225-F240 HydrophobicContact CG-CD1 4.25Å; Y225-F240 HydrophobicContact CG-CE1 4.09Å; Y225-F240 AromaticContact CZ-CD1 3.79Å; Y225-V243 HydrophobicContact CD1-CB 4.32Å; Y225-V243 HydrophobicContact CD1-CG1 4.31Å; Y225-V243 HydrophobicContact CE1-CB 4.3Å; Y225-V243 HydrophobicContact CE1-CG1 4.44Å; Y225-V243 WeakPolarHBondContact CE1-O 3.38Å; Y225-P245 HydrophobicContact CE1-CG 4.27Å; Y225-P245 HydrophobicContact CE2-CG 4.11Å; Y225-P245 WeakPolarHBondContact OH-CG 3.28Å
226V87.3Confident91.8Very high120 Ų12058.8 Ų58.873%0.72731%0.305SS*.  trans-92.294.7179.8-1770000108.9M239V226-M239 WeakPolarHBondContact O-CE 3.13Å
227M87.8Confident91.4Very high6 Ų659.6 Ų59.63%0.0331%0.31CS..  trans-120142.1-179.2-62177.7177.100110.8P185 Y225 I236 M239 F240P185-M227 HydrophobicContact CB-CB 4.32Å; P185-M227 HydrophobicContact CG-CB 4.16Å; Y225-M227 HydrophobicContact CG-CE 4.21Å; Y225-M227 PolarHBondContact O-N 3.26Å; M227-I236 HydrophobicContact CE-CB 4.36Å; M227-I236 HydrophobicContact CE-CG1 4.42Å; M227-I236 HydrophobicContact CE-CG2 3.75Å; M227-I236 HydrophobicContact SD-CG1 4.08Å; M227-I236 HydrophobicContact SD-CG2 3.98Å; M227-M239 HydrophobicContact CE-CB 4.17Å; M227-M239 HydrophobicContact CE-CE 4.45Å; M227-M239 HydrophobicContact CE-CG 4.15Å; M227-M239 HydrophobicContact CE-SD 3.47Å; M227-M239 WeakPolarHBondContact CE-SD 3.39Å; M227-M239 HydrophobicContact CG-CE 3.94Å; M227-M239 HydrophobicContact CG-SD 3.61Å; M227-M239 HydrophobicContact SD-SD 4.43Å; M227-F240 HydrophobicContact CE-CD1 3.99Å; M227-F240 HydrophobicContact CE-CE1 3.46Å; M227-F240 VanDerWaalsContact CE-CE1 3.46Å; M227-F240 HydrophobicContact CE-CE2 4.18Å; M227-F240 HydrophobicContact CE-CZ 3.59Å; M227-F240 HydrophobicContact SD-CZ 4.32Å
228R82Confident91.1Very high186 Ų18664 Ų6470%0.70233%0.33SS*.  trans-101160172.4-62.6-176.2-177.2-174.11.7109.7N230 T231R228-N230 WeakPolarHBondContact CB-OD1 3.45Å; R228-N230 PolarHBondContact O-N 3.42Å; R228-T231 PolarHBondContact N-OG1 2.92Å; R228-T231 WeakPolarHBondContact O-CB 3.18Å; R228-T231 PolarHBondContact O-N 3.38Å; R228-T231 VanDerWaalsContact O-N 3.17Å; R228-T231 PolarHBondContact O-OG1 3.15Å; R228-T231 VanDerWaalsContact O-OG1 3.12Å
229S79.3Confident90.8Very high102 Ų10265.6 Ų65.671%0.71334%0.338SS*.THydrogen-bonded Turntrans-61.8-27.1177.451.60000113K184K184-S229 WeakPolarHBondContact CD-O 3.32Å; K184-S229 VanDerWaalsContact CE-O 3.28Å; K184-S229 WeakPolarHBondContact CE-O 3.43Å; K184-S229 PolarHBondContact NZ-O 3.02Å
230N86.1Confident90.6Very high120 Ų12064.8 Ų64.864%0.64233%0.333SS*.THydrogen-bonded Turntrans-91.9-1.6178.668.4-21.1000114.4R228 Q232R228-N230 WeakPolarHBondContact CB-OD1 3.45Å; R228-N230 PolarHBondContact O-N 3.42Å; N230-Q232 PolarHBondContact O-N 3.41Å
231T88.8Confident90.3Very high18 Ų1866.8 Ų66.811%0.1135%0.346CS..  trans-61.7135.2176.8-52.40000110.2K184 R228 E235 I236K184-T231 PolarHBondContact NZ-O 3.45Å; R228-T231 PolarHBondContact N-OG1 2.92Å; R228-T231 WeakPolarHBondContact O-CB 3.18Å; R228-T231 PolarHBondContact O-N 3.38Å; R228-T231 VanDerWaalsContact O-N 3.17Å; R228-T231 PolarHBondContact O-OG1 3.15Å; R228-T231 VanDerWaalsContact O-OG1 3.12Å; T231-E235 HydrophobicContact CG2-CB 3.91Å; T231-E235 WeakPolarHBondContact CG2-OE2 3.36Å; T231-I236 HydrophobicContact CG2-CD1 4.32Å; T231-I236 HydrophobicContact CG2-CG1 3.7Å
232Q90.3Very high90.1Very high122 Ų12271.2 Ų71.257%0.5735%0.35SS*.  trans-76.3153.4-177.8-62.7-173.424.100111.5N230 N234 E235 I236N230-Q232 PolarHBondContact O-N 3.41Å; Q232-N234 VanDerWaalsContact C-N 3.33Å; Q232-N234 WeakPolarHBondContact CB-OD1 3.28Å; Q232-N234 PolarHBondContact O-N 3.13Å; Q232-E235 PolarHBondContact O-N 2.77Å; Q232-I236 WeakPolarHBondContact O-CG1 3.43Å; Q232-I236 PolarHBondContact O-N 2.92Å
233S88.8Confident90Very high25 Ų2569.6 Ų69.618%0.17535%0.346CS..Hα-helixtrans-59.3-40.9-176.1-56.60000113I236 L237S233-I236 WeakPolarHBondContact O-CB 3.24Å; S233-I236 PolarHBondContact O-N 2.8Å; S233-L237 WeakPolarHBondContact O-CG 3.4Å; S233-L237 PolarHBondContact O-N 2.97Å
234N88.4Confident89.8Confident71 Ų7173 Ų7338%0.3837%0.366SS..Hα-helixtrans-63.4-42.6177.561.3-16.5000112.6E196 Q232 I236 L237 Q238E196-N234 PolarHBondContact OE1-N 3.36Å; Q232-N234 VanDerWaalsContact C-N 3.33Å; Q232-N234 WeakPolarHBondContact CB-OD1 3.28Å; Q232-N234 PolarHBondContact O-N 3.13Å; N234-I236 VanDerWaalsContact C-N 3.33Å; N234-L237 PolarHBondContact O-N 3.06Å; N234-Q238 WeakPolarHBondContact O-CG 3.26Å; N234-Q238 PolarHBondContact O-N 2.98Å
235E91.6Very high89.7Confident103 Ų10373.6 Ų73.648%0.48137%0.369SS..Hα-helixtrans-64.1-39.6174.7-77.8-175.4162.300111.4T231 Q232 Q238 M239T231-E235 HydrophobicContact CG2-CB 3.91Å; T231-E235 WeakPolarHBondContact CG2-OE2 3.36Å; Q232-E235 PolarHBondContact O-N 2.77Å; E235-Q238 PolarHBondContact O-N 3.2Å; E235-M239 WeakPolarHBondContact O-CB 3.46Å; E235-M239 PolarHBondContact O-N 3.49Å
236I92.1Very high89.7Confident0 Ų077.6 Ų77.60%039%0.394CS..Hα-helixtrans-61.8-48176.2-72169000110.6K184 F192 M227 T231 Q232 S233 N234 Q238 M239 F240K184-I236 HydrophobicContact CB-CD1 4.44Å; K184-I236 HydrophobicContact CD-CD1 4.01Å; F192-I236 HydrophobicContact CD1-CD1 4.3Å; F192-I236 HydrophobicContact CD1-CG2 4.29Å; F192-I236 HydrophobicContact CD2-CG2 3.72Å; F192-I236 HydrophobicContact CE1-CD1 3.61Å; F192-I236 HydrophobicContact CE1-CG2 4.14Å; F192-I236 HydrophobicContact CE2-CG2 3.55Å; F192-I236 HydrophobicContact CG-CG2 4.09Å; F192-I236 HydrophobicContact CZ-CD1 3.83Å; F192-I236 HydrophobicContact CZ-CG2 3.77Å; M227-I236 HydrophobicContact CE-CB 4.36Å; M227-I236 HydrophobicContact CE-CG1 4.42Å; M227-I236 HydrophobicContact CE-CG2 3.75Å; M227-I236 HydrophobicContact SD-CG1 4.08Å; M227-I236 HydrophobicContact SD-CG2 3.98Å; T231-I236 HydrophobicContact CG2-CD1 4.32Å; T231-I236 HydrophobicContact CG2-CG1 3.7Å; Q232-I236 WeakPolarHBondContact O-CG1 3.43Å; Q232-I236 PolarHBondContact O-N 2.92Å; S233-I236 WeakPolarHBondContact O-CB 3.24Å; S233-I236 PolarHBondContact O-N 2.8Å; N234-I236 VanDerWaalsContact C-N 3.33Å; I236-Q238 PolarHBondContact O-N 2.84Å; I236-M239 WeakPolarHBondContact O-CB 3.39Å; I236-M239 PolarHBondContact O-N 3.09Å; I236-M239 VanDerWaalsContact O-N 3.14Å; I236-F240 HydrophobicContact CG2-CD2 3.98Å; I236-F240 HydrophobicContact CG2-CE2 3.38Å; I236-F240 HydrophobicContact CG2-CZ 3.95Å; I236-F240 WeakPolarHBondContact O-CD2 3.18Å; I236-F240 PolarHBondContact O-N 3.22Å
237L90.7Very high90.2Very high17 Ų1773.7 Ų73.79%0.08937%0.367CS..Hα-helixtrans-61.8-44.7177.3-72.4175000111.9F192 Q193 E196 S233 N234 M239 F240 H241F192-L237 HydrophobicContact CB-CD1 4.14Å; F192-L237 HydrophobicContact CB-CD2 3.85Å; F192-L237 HydrophobicContact CB-CG 3.87Å; Q193-L237 HydrophobicContact CG-CD1 4.27Å; Q193-L237 HydrophobicContact CG-CD2 3.66Å; E196-L237 VanDerWaalsContact OE2-CD1 3.3Å; E196-L237 WeakPolarHBondContact OE2-CD1 3.45Å; S233-L237 WeakPolarHBondContact O-CG 3.4Å; S233-L237 PolarHBondContact O-N 2.97Å; N234-L237 PolarHBondContact O-N 3.06Å; L237-M239 VanDerWaalsContact C-N 3.26Å; L237-M239 PolarHBondContact O-N 2.9Å; L237-F240 HydrophobicContact CD2-CD2 4.48Å; L237-F240 PolarHBondContact O-N 3.13Å; L237-H241 PolarHBondContact O-CD2 3.07Å; L237-H241 PolarHBondContact O-N 3.36Å
238Q91.3Very high90.6Very high99 Ų9975.3 Ų75.346%0.46338%0.377SS..Hα-helixtrans-60.1-37.8174.1-73-173.524.200112.3N234 E235 I236 H241 K242N234-Q238 WeakPolarHBondContact O-CG 3.26Å; N234-Q238 PolarHBondContact O-N 2.98Å; E235-Q238 PolarHBondContact O-N 3.2Å; I236-Q238 PolarHBondContact O-N 2.84Å; Q238-H241 PolarHBondContact O-N 3.07Å; Q238-K242 HydrophobicContact CB-CD 4.49Å; Q238-K242 WeakPolarHBondContact O-CB 3.47Å; Q238-K242 VanDerWaalsContact O-CG 3.3Å; Q238-K242 WeakPolarHBondContact O-CG 3.48Å; Q238-K242 PolarHBondContact O-N 3.12Å
239M93.4Very high91.2Very high42 Ų4271 Ų7121%0.20738%0.381CS..Hα-helixtrans-62.9-44.6177.1-171.4-176.8-56.800111.4Y225 V226 M227 E235 I236 L237 H241 K242 V243Y225-M239 HydrophobicContact CD1-CG 4.24Å; Y225-M239 HydrophobicContact CD1-SD 4.4Å; V226-M239 WeakPolarHBondContact O-CE 3.13Å; M227-M239 HydrophobicContact CE-CB 4.17Å; M227-M239 HydrophobicContact CE-CE 4.45Å; M227-M239 HydrophobicContact CE-CG 4.15Å; M227-M239 HydrophobicContact CE-SD 3.47Å; M227-M239 WeakPolarHBondContact CE-SD 3.39Å; M227-M239 HydrophobicContact CG-CE 3.94Å; M227-M239 HydrophobicContact CG-SD 3.61Å; M227-M239 HydrophobicContact SD-SD 4.43Å; E235-M239 WeakPolarHBondContact O-CB 3.46Å; E235-M239 PolarHBondContact O-N 3.49Å; I236-M239 WeakPolarHBondContact O-CB 3.39Å; I236-M239 PolarHBondContact O-N 3.09Å; I236-M239 VanDerWaalsContact O-N 3.14Å; L237-M239 VanDerWaalsContact C-N 3.26Å; L237-M239 PolarHBondContact O-N 2.9Å; M239-H241 PolarHBondContact O-N 3.33Å; M239-K242 PolarHBondContact O-N 3.21Å; M239-V243 HydrophobicContact CG-CB 4.24Å; M239-V243 HydrophobicContact CG-CG2 3.76Å; M239-V243 VanDerWaalsContact O-CB 3.29Å; M239-V243 WeakPolarHBondContact O-CB 3.39Å; M239-V243 PolarHBondContact O-N 3.45Å
240F93.6Very high92Very high4 Ų470.6 Ų70.62%0.01838%0.384CS..Hα-helixtrans-59.4-36176.6-68-46.7000112.5P189 F192 W209 Y225 M227 I236 L237 I265P189-F240 HydrophobicContact CB-CD2 3.72Å; P189-F240 HydrophobicContact CB-CE2 3.98Å; P189-F240 HydrophobicContact CB-CG 4.37Å; P189-F240 HydrophobicContact CG-CB 4.49Å; P189-F240 HydrophobicContact CG-CD1 4.33Å; P189-F240 HydrophobicContact CG-CD2 3.68Å; P189-F240 HydrophobicContact CG-CE1 4.48Å; P189-F240 HydrophobicContact CG-CE2 3.83Å; P189-F240 HydrophobicContact CG-CG 3.94Å; P189-F240 HydrophobicContact CG-CZ 4.23Å; F192-F240 HydrophobicContact CD2-CE2 4.06Å; F192-F240 HydrophobicContact CE2-CE2 4.06Å; F192-F240 HydrophobicContact CE2-CZ 4.47Å; W209-F240 HydrophobicContact CH2-CD1 4.3Å; W209-F240 HydrophobicContact CH2-CE1 4.26Å; W209-F240 HydrophobicContact CZ2-CD1 4.07Å; W209-F240 AromaticContact CZ2-CE1 3.59Å; W209-F240 HydrophobicContact CZ2-CE1 3.59Å; W209-F240 HydrophobicContact CZ2-CZ 4.1Å; Y225-F240 HydrophobicContact CD1-CD1 4.09Å; Y225-F240 HydrophobicContact CD1-CE1 4.39Å; Y225-F240 HydrophobicContact CD2-CD1 4.17Å; Y225-F240 AromaticContact CD2-CE1 3.83Å; Y225-F240 HydrophobicContact CD2-CE1 3.83Å; Y225-F240 AromaticContact CE1-CD1 3.85Å; Y225-F240 HydrophobicContact CE1-CD1 3.85Å; Y225-F240 HydrophobicContact CE1-CE1 4.46Å; Y225-F240 AromaticContact CE2-CD1 3.96Å; Y225-F240 HydrophobicContact CE2-CD1 3.96Å; Y225-F240 AromaticContact CE2-CE1 3.93Å; Y225-F240 HydrophobicContact CE2-CE1 3.93Å; Y225-F240 HydrophobicContact CG-CD1 4.25Å; Y225-F240 HydrophobicContact CG-CE1 4.09Å; Y225-F240 AromaticContact CZ-CD1 3.79Å; M227-F240 HydrophobicContact CE-CD1 3.99Å; M227-F240 HydrophobicContact CE-CE1 3.46Å; M227-F240 VanDerWaalsContact CE-CE1 3.46Å; M227-F240 HydrophobicContact CE-CE2 4.18Å; M227-F240 HydrophobicContact CE-CZ 3.59Å; M227-F240 HydrophobicContact SD-CZ 4.32Å; I236-F240 HydrophobicContact CG2-CD2 3.98Å; I236-F240 HydrophobicContact CG2-CE2 3.38Å; I236-F240 HydrophobicContact CG2-CZ 3.95Å; I236-F240 WeakPolarHBondContact O-CD2 3.18Å; I236-F240 PolarHBondContact O-N 3.22Å; L237-F240 HydrophobicContact CD2-CD2 4.48Å; L237-F240 PolarHBondContact O-N 3.13Å; F240-I265 HydrophobicContact CB-CD1 4.16Å; F240-I265 WeakPolarHBondContact O-CD1 3.46Å
241H89.5Confident92.6Very high122 Ų12266.1 Ų66.157%0.56536%0.359SS*.Hα-helixtrans-78.7-33.6178-71.6-64.9000114.4L237 Q238 M239L237-H241 PolarHBondContact O-CD2 3.07Å; L237-H241 PolarHBondContact O-N 3.36Å; Q238-H241 PolarHBondContact O-N 3.07Å; M239-H241 PolarHBondContact O-N 3.33Å
242K91.4Very high93Very high148 Ų14866.8 Ų66.864%0.64336%0.364SS*.Hα-helixtrans-92.3-28.6-173.6-69172.8179.61720113.6Q238 M239Q238-K242 HydrophobicContact CB-CD 4.49Å; Q238-K242 WeakPolarHBondContact O-CB 3.47Å; Q238-K242 VanDerWaalsContact O-CG 3.3Å; Q238-K242 WeakPolarHBondContact O-CG 3.48Å; Q238-K242 PolarHBondContact O-N 3.12Å; M239-K242 PolarHBondContact O-N 3.21Å
243V92.1Very high93.4Very high61 Ų6167.1 Ų67.137%0.3737%0.369SS..  trans-104.7119.4-172.3-177.40000109.8Y225 M239Y225-V243 HydrophobicContact CD1-CB 4.32Å; Y225-V243 HydrophobicContact CD1-CG1 4.31Å; Y225-V243 HydrophobicContact CE1-CB 4.3Å; Y225-V243 HydrophobicContact CE1-CG1 4.44Å; Y225-V243 WeakPolarHBondContact CE1-O 3.38Å; M239-V243 HydrophobicContact CG-CB 4.24Å; M239-V243 HydrophobicContact CG-CG2 3.76Å; M239-V243 VanDerWaalsContact O-CB 3.29Å; M239-V243 WeakPolarHBondContact O-CB 3.39Å; M239-V243 PolarHBondContact O-N 3.45Å
244H91.2Very high93.8Very high153 Ų15370.5 Ų70.571%0.70838%0.382SS*.PPolyproline II helixtrans-93.8124.8170.3-63.3-59.4000110T246H244-T246 PolarHBondContact O-N 3.2Å
245P93.9Very high94.3Very high22 Ų2267.1 Ų67.114%0.14336%0.364CS..PPolyproline II helixtrans-54.9130.1175.6-27.735.7000111.6Y216 P224 Y225 Y247Y216-P245 HydrophobicContact CE2-CB 4.37Å; P224-P245 HydrophobicContact CB-CB 3.83Å; P224-P245 HydrophobicContact CB-CG 4.04Å; Y225-P245 HydrophobicContact CE1-CG 4.27Å; Y225-P245 HydrophobicContact CE2-CG 4.11Å; Y225-P245 WeakPolarHBondContact OH-CG 3.28Å; P245-Y247 HydrophobicContact CB-CE2 3.86Å; P245-Y247 WeakPolarHBondContact O-CD2 3.3Å; P245-Y247 VanDerWaalsContact O-CE2 3.28Å; P245-Y247 WeakPolarHBondContact O-CE2 3.11Å
246T95.1Very high94.6Very high89 Ų8963.2 Ų63.255%0.54635%0.346SS..PPolyproline II helixtrans-79.6128.8175-49.50000109.8Y216 H244Y216-T246 WeakPolarHBondContact CE2-O 3.38Å; Y216-T246 PolarHBondContact OH-O 2.88Å; H244-T246 PolarHBondContact O-N 3.2Å
247Y96.5Very high94.9Very high38 Ų3866 Ų6615%0.14937%0.365CS..  trans-110113.6175.9-66.1-87.9000109.3Y216 P245 W251 K256 L259 R260Y216-Y247 HydrophobicContact CD2-CE1 4.09Å; Y216-Y247 HydrophobicContact CE2-CD1 4.26Å; Y216-Y247 HydrophobicContact CE2-CE1 4.08Å; P245-Y247 HydrophobicContact CB-CE2 3.86Å; P245-Y247 WeakPolarHBondContact O-CD2 3.3Å; P245-Y247 VanDerWaalsContact O-CE2 3.28Å; P245-Y247 WeakPolarHBondContact O-CE2 3.11Å; Y247-W251 AromaticContact CD1-CE3 3.96Å; Y247-W251 HydrophobicContact CD1-CE3 3.96Å; Y247-W251 AromaticContact CD1-CZ3 3.73Å; Y247-W251 HydrophobicContact CD1-CZ3 3.73Å; Y247-W251 HydrophobicContact CE1-CZ3 4.37Å; Y247-K256 HydrophobicContact CD1-CB 4.47Å; Y247-K256 HydrophobicContact CD1-CG 4.26Å; Y247-K256 HydrophobicContact CG-CG 4.38Å; Y247-L259 HydrophobicContact CD1-CD1 4.42Å; Y247-L259 HydrophobicContact CE1-CB 3.73Å; Y247-L259 HydrophobicContact CE1-CD1 4.07Å; Y247-R260 HydrophobicContact CE2-CG 3.93Å
248P95.6Very high95.3Very high39 Ų3965.2 Ų65.225%0.25336%0.361SS..  trans-51.6140.1179.4-29.735.8000113.3A250 W251 K256P248-A250 PolarHBondContact O-N 3.19Å; P248-W251 HydrophobicContact CB-CD2 4.32Å; P248-W251 HydrophobicContact CB-CG 4.28Å; P248-W251 HydrophobicContact CG-CD2 4.1Å; P248-W251 HydrophobicContact CG-CH2 4.41Å; P248-W251 HydrophobicContact CG-CZ2 3.84Å; P248-W251 PolarHBondContact O-N 3.2Å; P248-W251 VanDerWaalsContact O-N 3.09Å; P248-K256 WeakPolarHBondContact O-CE 3.31Å; P248-K256 PolarHBondContact O-NZ 2.92Å
249A95.7Very high95.6Very high95 Ų9560.5 Ų60.579%0.78534%0.339SS*.THydrogen-bonded Turntrans-57.9-35.3178.600000112W251 K256A249-W251 PolarHBondContact O-N 2.92Å; A249-K256 PolarHBondContact O-NZ 3.37Å
250A96.1Very high95.8Very high94 Ų9464.6 Ų64.678%0.77735%0.352SS*.THydrogen-bonded Turntrans-61.7-20.7178.400000114.6P248P248-A250 PolarHBondContact O-N 3.19Å
251W97.8Very high96Very high27 Ų2768.8 Ų68.810%0.10237%0.37CS..SBendtrans-75.5146.9178.4-59.8-12.4000112.2E120 Y216 L219 R220 Y247 P248 A249 K256 L259E120-W251 WeakPolarHBondContact OE1-CA 3.06Å; E120-W251 WeakPolarHBondContact OE1-CB 3.49Å; Y216-W251 AromaticContact CD2-CH2 3.87Å; Y216-W251 HydrophobicContact CD2-CH2 3.87Å; Y216-W251 AromaticContact CD2-CZ3 3.88Å; Y216-W251 HydrophobicContact CD2-CZ3 3.88Å; Y216-W251 AromaticContact CE2-CH2 3.83Å; Y216-W251 HydrophobicContact CE2-CH2 3.83Å; Y216-W251 AromaticContact CE2-CZ3 3.87Å; Y216-W251 HydrophobicContact CE2-CZ3 3.87Å; Y216-W251 HydrophobicContact CG-CH2 4.34Å; L219-W251 HydrophobicContact CB-CH2 3.91Å; L219-W251 HydrophobicContact CB-CZ2 3.43Å; L219-W251 VanDerWaalsContact CB-CZ2 3.43Å; L219-W251 HydrophobicContact CD1-CH2 4.48Å; L219-W251 HydrophobicContact CD1-CZ2 4.47Å; R220-W251 HydrophobicContact CB-CH2 4.03Å; R220-W251 HydrophobicContact CB-CZ2 3.84Å; R220-W251 HydrophobicContact CG-CZ2 4.3Å; Y247-W251 AromaticContact CD1-CE3 3.96Å; Y247-W251 HydrophobicContact CD1-CE3 3.96Å; Y247-W251 AromaticContact CD1-CZ3 3.73Å; Y247-W251 HydrophobicContact CD1-CZ3 3.73Å; Y247-W251 HydrophobicContact CE1-CZ3 4.37Å; P248-W251 HydrophobicContact CB-CD2 4.32Å; P248-W251 HydrophobicContact CB-CG 4.28Å; P248-W251 HydrophobicContact CG-CD2 4.1Å; P248-W251 HydrophobicContact CG-CH2 4.41Å; P248-W251 HydrophobicContact CG-CZ2 3.84Å; P248-W251 PolarHBondContact O-N 3.2Å; P248-W251 VanDerWaalsContact O-N 3.09Å; A249-W251 PolarHBondContact O-N 2.92Å; W251-K256 HydrophobicContact CB-CG 4.16Å; W251-K256 WeakPolarHBondContact O-CE 3.45Å; W251-K256 PolarHBondContact O-NZ 3.18Å; W251-L259 HydrophobicContact CE3-CD1 4.07Å; W251-L259 HydrophobicContact CH2-CD1 4.44Å; W251-L259 HydrophobicContact CZ3-CD1 3.61Å
252S98.2Very high96.4Very high32 Ų3263 Ų6322%0.22434%0.343CS..  trans-58.1153.4174.771.90000112.1E120 E254 M255 K256E120-S252 PolarHBondContact OE1-N 3.44Å; E120-S252 WeakPolarHBondContact OE2-CB 3.42Å; E120-S252 PolarHBondContact OE2-N 3.09Å; E120-S252 PolarHBondContact OE2-OG 3.35Å; S252-E254 WeakPolarHBondContact CB-OE2 3.47Å; S252-E254 PolarHBondContact O-N 3.42Å; S252-M255 WeakPolarHBondContact OG-CB 3.43Å; S252-M255 PolarHBondContact OG-N 3.22Å; S252-K256 WeakPolarHBondContact O-CG 3.47Å; S252-K256 PolarHBondContact O-N 3.35Å; S252-K256 VanDerWaalsContact O-N 3.16Å
253L98.1Very high96.7Very high129 Ų12956.4 Ų56.468%0.67532%0.315SS*.Hα-helixtrans-65.5-33.6178.1-70178000110.8K256 S257L253-K256 PolarHBondContact O-N 2.76Å; L253-S257 WeakPolarHBondContact O-CB 3.21Å; L253-S257 PolarHBondContact O-N 3.27Å
254E97.9Very high97Very high95 Ų9554.9 Ų54.944%0.44431%0.307SS..Hα-helixtrans-68.3-48.3-178.8-59.270.6-155.700110.9S252 K256 S257 L258 Y282S252-E254 WeakPolarHBondContact CB-OE2 3.47Å; S252-E254 PolarHBondContact O-N 3.42Å; E254-K256 VanDerWaalsContact C-N 3.35Å; E254-K256 PolarHBondContact O-N 3.25Å; E254-S257 WeakPolarHBondContact O-CB 3.32Å; E254-S257 PolarHBondContact O-N 2.65Å; E254-S257 VanDerWaalsContact O-N 3.14Å; E254-L258 PolarHBondContact O-N 3.35Å; E254-Y282 HydrophobicContact CB-CD1 4.24Å; E254-Y282 HydrophobicContact CB-CD2 3.26Å; E254-Y282 HydrophobicContact CB-CE2 3.6Å; E254-Y282 HydrophobicContact CB-CG 3.61Å; E254-Y282 HydrophobicContact CG-CD2 3.86Å; E254-Y282 HydrophobicContact CG-CE2 4.36Å; E254-Y282 HydrophobicContact CG-CG 4.45Å
255M98.3Very high97.1Very high0 Ų050.2 Ų50.20%029%0.286CS..Hα-helixtrans-62-42.1174.6-179.65976.600111.7E120 K124 L219 S252 S257 L258 L259 Y282E120-M255 HydrophobicContact CB-CE 4.04Å; E120-M255 HydrophobicContact CG-CE 4.27Å; E120-M255 HydrophobicContact CG-CG 4.31Å; E120-M255 WeakPolarHBondContact O-CE 3.46Å; E120-M255 WeakPolarHBondContact OE2-CB 3.49Å; K124-M255 HydrophobicContact CB-CE 4.29Å; L219-M255 HydrophobicContact CD1-CE 4.17Å; L219-M255 HydrophobicContact CD1-CG 3.69Å; L219-M255 HydrophobicContact CD1-SD 3.77Å; S252-M255 WeakPolarHBondContact OG-CB 3.43Å; S252-M255 PolarHBondContact OG-N 3.22Å; M255-S257 VanDerWaalsContact C-N 3.3Å; M255-S257 PolarHBondContact O-N 2.87Å; M255-L258 PolarHBondContact O-N 3.17Å; M255-L258 HydrophobicContact SD-CD2 4.32Å; M255-L259 HydrophobicContact CG-CD1 4.14Å; M255-L259 WeakPolarHBondContact O-CG 3.43Å; M255-L259 PolarHBondContact O-N 3Å; M255-L259 HydrophobicContact SD-CD1 4.23Å; M255-L259 HydrophobicContact SD-CG 4.11Å; M255-Y282 HydrophobicContact CE-CE1 4.33Å
256K98.4Very high97Very high22 Ų2252.3 Ų52.310%0.09630%0.297CS..Hα-helixtrans-59.9-42174-68.3170.2-179.8148.80111.4Y247 P248 A249 W251 S252 L253 E254 R260Y247-K256 HydrophobicContact CD1-CB 4.47Å; Y247-K256 HydrophobicContact CD1-CG 4.26Å; Y247-K256 HydrophobicContact CG-CG 4.38Å; P248-K256 WeakPolarHBondContact O-CE 3.31Å; P248-K256 PolarHBondContact O-NZ 2.92Å; A249-K256 PolarHBondContact O-NZ 3.37Å; W251-K256 HydrophobicContact CB-CG 4.16Å; W251-K256 WeakPolarHBondContact O-CE 3.45Å; W251-K256 PolarHBondContact O-NZ 3.18Å; S252-K256 WeakPolarHBondContact O-CG 3.47Å; S252-K256 PolarHBondContact O-N 3.35Å; S252-K256 VanDerWaalsContact O-N 3.16Å; L253-K256 PolarHBondContact O-N 2.76Å; E254-K256 VanDerWaalsContact C-N 3.35Å; E254-K256 PolarHBondContact O-N 3.25Å; K256-R260 VanDerWaalsContact O-CG 3.27Å; K256-R260 WeakPolarHBondContact O-CG 3.17Å; K256-R260 PolarHBondContact O-N 2.82Å; K256-R260 VanDerWaalsContact O-N 3.09Å
257S97.9Very high96.9Very high57 Ų5749.5 Ų49.540%0.39928%0.279SS..Hα-helixtrans-64-48.4178.2-170.90000111.5L253 E254 M255 L259 R260 K261L253-S257 WeakPolarHBondContact O-CB 3.21Å; L253-S257 PolarHBondContact O-N 3.27Å; E254-S257 WeakPolarHBondContact O-CB 3.32Å; E254-S257 PolarHBondContact O-N 2.65Å; E254-S257 VanDerWaalsContact O-N 3.14Å; M255-S257 VanDerWaalsContact C-N 3.3Å; M255-S257 PolarHBondContact O-N 2.87Å; S257-L259 PolarHBondContact O-N 3.17Å; S257-R260 PolarHBondContact O-N 3.35Å; S257-K261 PolarHBondContact O-N 2.78Å
258L98.4Very high96.7Very high2 Ų255.6 Ų55.61%0.0131%0.309CS..Hα-helixtrans-55.9-52.2176.4171.961.4000111.9I127 E254 M255 R260 K261 L262 I271 L277 L280 Y282 M283I127-L258 HydrophobicContact CD1-CD2 3.67Å; I127-L258 HydrophobicContact CD1-CG 4.47Å; I127-L258 HydrophobicContact CG2-CD2 4.49Å; E254-L258 PolarHBondContact O-N 3.35Å; M255-L258 PolarHBondContact O-N 3.17Å; M255-L258 HydrophobicContact SD-CD2 4.32Å; L258-R260 VanDerWaalsContact C-N 3.31Å; L258-R260 PolarHBondContact O-N 3.07Å; L258-K261 PolarHBondContact O-N 3.12Å; L258-K261 VanDerWaalsContact O-N 3.11Å; L258-L262 HydrophobicContact CD1-CD1 4.09Å; L258-L262 HydrophobicContact CD1-CG 4.36Å; L258-L262 HydrophobicContact CG-CD1 4.23Å; L258-L262 PolarHBondContact O-N 3.48Å; L258-I271 HydrophobicContact CD1-CD1 4.49Å; L258-L277 HydrophobicContact CD1-CD1 3.51Å; L258-L280 HydrophobicContact CD1-CD1 3.59Å; L258-Y282 HydrophobicContact CB-CD1 4.21Å; L258-Y282 HydrophobicContact CD2-CD1 3.93Å; L258-Y282 HydrophobicContact CD2-CE1 3.92Å; L258-M283 HydrophobicContact CD1-CE 3.95Å; L258-M283 HydrophobicContact CD2-CE 3.58Å; L258-M283 HydrophobicContact CG-CE 4.4Å
259L98.5Very high96.7Very high0 Ų060.9 Ų60.90%033%0.328CS..Hα-helixtrans-62.4-37.2-179.7-70.1173.7000112.2A215 Y216 L219 Y247 W251 M255 S257 K261 L262 L263A215-L259 HydrophobicContact CB-CD2 3.86Å; Y216-L259 HydrophobicContact CD2-CD1 4.27Å; L219-L259 HydrophobicContact CD1-CD1 4.07Å; Y247-L259 HydrophobicContact CD1-CD1 4.42Å; Y247-L259 HydrophobicContact CE1-CB 3.73Å; Y247-L259 HydrophobicContact CE1-CD1 4.07Å; W251-L259 HydrophobicContact CE3-CD1 4.07Å; W251-L259 HydrophobicContact CH2-CD1 4.44Å; W251-L259 HydrophobicContact CZ3-CD1 3.61Å; M255-L259 HydrophobicContact CG-CD1 4.14Å; M255-L259 WeakPolarHBondContact O-CG 3.43Å; M255-L259 PolarHBondContact O-N 3Å; M255-L259 HydrophobicContact SD-CD1 4.23Å; M255-L259 HydrophobicContact SD-CG 4.11Å; S257-L259 PolarHBondContact O-N 3.17Å; L259-K261 VanDerWaalsContact C-N 3.33Å; L259-K261 PolarHBondContact O-N 3.4Å; L259-L262 PolarHBondContact O-N 3.41Å; L259-L263 VanDerWaalsContact O-CB 3.23Å; L259-L263 WeakPolarHBondContact O-CB 3.28Å; L259-L263 WeakPolarHBondContact O-CG 3.39Å; L259-L263 PolarHBondContact O-N 3.28Å
260R97.8Very high96.7Very high127 Ų12756.6 Ų56.648%0.47929%0.291SS..Hα-helixtrans-65-35.2174.7-75-179.1-164115-4112.8Y247 K256 S257 L258 L263 C264Y247-R260 HydrophobicContact CE2-CG 3.93Å; K256-R260 VanDerWaalsContact O-CG 3.27Å; K256-R260 WeakPolarHBondContact O-CG 3.17Å; K256-R260 PolarHBondContact O-N 2.82Å; K256-R260 VanDerWaalsContact O-N 3.09Å; S257-R260 PolarHBondContact O-N 3.35Å; L258-R260 VanDerWaalsContact C-N 3.31Å; L258-R260 PolarHBondContact O-N 3.07Å; R260-L263 CarbonylContact O-C 3.53Å; R260-C264 PolarHBondContact O-N 3.06Å; R260-C264 VanDerWaalsContact O-N 3.14Å
261K97.9Very high96.8Very high92 Ų9252.4 Ų52.440%0.426%0.256SS..Hα-helixtrans-71.3-36.9176.1-71.9-169.4176.4-168.10112.2S257 L258 L259 R270 I271 L280S257-K261 PolarHBondContact O-N 2.78Å; L258-K261 PolarHBondContact O-N 3.12Å; L258-K261 VanDerWaalsContact O-N 3.11Å; L259-K261 VanDerWaalsContact C-N 3.33Å; L259-K261 PolarHBondContact O-N 3.4Å; K261-R270 WeakPolarHBondContact O-CA 3.49Å; K261-R270 WeakPolarHBondContact O-CG 3.43Å; K261-I271 HydrophobicContact CB-CD1 3.5Å; K261-I271 HydrophobicContact CB-CG1 3.91Å; K261-I271 HydrophobicContact CD-CD1 4Å; K261-I271 HydrophobicContact CD-CG1 4.47Å; K261-I271 HydrophobicContact CG-CD1 4.41Å; K261-I271 PolarHBondContact O-N 3.17Å; K261-L280 HydrophobicContact CD-CD2 3.53Å
262L98.4Very high96.7Very high0 Ų052.2 Ų52.20%026%0.259CS..Hα-helixtrans-71.6-39.8173.4-69.8169.1000112.3I127 W208 L258 L259 C264 R270 I271I127-L262 HydrophobicContact CD1-CD1 4.49Å; W208-L262 HydrophobicContact CB-CD2 4.44Å; W208-L262 HydrophobicContact CE3-CD2 3.94Å; L258-L262 HydrophobicContact CD1-CD1 4.09Å; L258-L262 HydrophobicContact CD1-CG 4.36Å; L258-L262 HydrophobicContact CG-CD1 4.23Å; L258-L262 PolarHBondContact O-N 3.48Å; L259-L262 PolarHBondContact O-N 3.41Å; L262-C264 VanDerWaalsContact C-N 3.27Å; L262-C264 PolarHBondContact O-N 2.75Å; L262-R270 VanDerWaalsContact O-CD 3.28Å; L262-R270 WeakPolarHBondContact O-CD 3.39Å; L262-R270 VanDerWaalsContact O-CG 3.26Å; L262-R270 WeakPolarHBondContact O-CG 3.43Å; L262-I271 HydrophobicContact CD2-CB 4.19Å; L262-I271 HydrophobicContact CD2-CG2 4.31Å
263L97.8Very high96.6Very high11 Ų1152 Ų526%0.05826%0.257CS..THydrogen-bonded Turntrans-92.728.2179.2-60178.9000112.6W209 I213 Y216 P224 L259 R260 I265W209-L263 HydrophobicContact CD2-CD2 4.18Å; W209-L263 HydrophobicContact CE3-CD2 4.34Å; W209-L263 VanDerWaalsContact CZ3-C 3.43Å; W209-L263 HydrophobicContact CZ3-CB 4.4Å; W209-L263 WeakPolarHBondContact CZ3-O 3.22Å; I213-L263 HydrophobicContact CD1-CD2 3.48Å; I213-L263 VanDerWaalsContact CD1-CD2 3.48Å; I213-L263 HydrophobicContact CG1-CD2 3.76Å; Y216-L263 HydrophobicContact CD2-CD1 4.46Å; P224-L263 HydrophobicContact CG-CD1 4.17Å; L259-L263 VanDerWaalsContact O-CB 3.23Å; L259-L263 WeakPolarHBondContact O-CB 3.28Å; L259-L263 WeakPolarHBondContact O-CG 3.39Å; L259-L263 PolarHBondContact O-N 3.28Å; R260-L263 CarbonylContact O-C 3.53Å; L263-I265 PolarHBondContact O-N 3.22Å
264C96.4Very high96.6Very high29 Ų2947.4 Ų47.420%0.19623%0.233CC..  trans-75.1122.1174.7-164.50000109.6R260 L262 D266 R270R260-C264 PolarHBondContact O-N 3.06Å; R260-C264 VanDerWaalsContact O-N 3.14Å; L262-C264 VanDerWaalsContact C-N 3.27Å; L262-C264 PolarHBondContact O-N 2.75Å; C264-D266 VanDerWaalsContact C-N 3.3Å; C264-D266 PolarHBondContact O-N 3.14Å; C264-R270 HydrophobicContact CB-CB 3.98Å; C264-R270 HydrophobicContact CB-CG 4.24Å; C264-R270 PolarHBondContact O-NE 3.49Å; C264-R270 PolarHBondContact O-NH2 3.3Å; C264-R270 VanDerWaalsContact O-NH2 3.17Å
265I94.4Very high96.6Very high54 Ų5446 Ų4628%0.27724%0.237SC..SBendtrans-65.5-38.5179.9-66169000110.6P189 W209 F240 L263 V267 R270P189-I265 HydrophobicContact CB-CG2 4.37Å; P189-I265 HydrophobicContact CG-CG1 4.39Å; P189-I265 HydrophobicContact CG-CG2 4.17Å; W209-I265 HydrophobicContact CH2-CG1 4.06Å; W209-I265 HydrophobicContact CZ3-CG1 4.16Å; F240-I265 HydrophobicContact CB-CD1 4.16Å; F240-I265 WeakPolarHBondContact O-CD1 3.46Å; L263-I265 PolarHBondContact O-N 3.22Å; I265-V267 PolarHBondContact O-N 3.1Å; I265-R270 PolarHBondContact O-NH2 3.34Å
266D92.7Very high96.6Very high67 Ų6749.7 Ų49.736%0.35826%0.255SS..SBendtrans-70.1108.9175.1-176.1-10.8000109.9C264 Q268 K269 R270C264-D266 VanDerWaalsContact C-N 3.3Å; C264-D266 PolarHBondContact O-N 3.14Å; D266-Q268 PolarHBondContact O-N 2.9Å; D266-Q268 PolarHBondContact OD1-N 2.75Å; D266-Q268 VanDerWaalsContact OD1-N 3.11Å; D266-K269 HydrophobicContact CB-CB 4.28Å; D266-K269 HydrophobicContact CB-CD 4.24Å; D266-K269 HydrophobicContact CB-CG 4.4Å; D266-K269 PolarHBondContact O-N 3.04Å; D266-K269 VanDerWaalsContact OD2-CD 3.27Å; D266-K269 WeakPolarHBondContact OD2-CD 3.32Å; D266-K269 WeakPolarHBondContact OD2-CE 3.28Å; D266-K269 IonicContact OD2-NZ 3.27Å; D266-K269 PolarHBondContact OD2-NZ 2.65Å; D266-K269 VanDerWaalsContact OD2-NZ 3.14Å; D266-R270 PolarHBondContact O-N 2.81Å
267V92.4Very high96.6Very high30 Ų3048.7 Ų48.718%0.18225%0.25CS..THydrogen-bonded Turntrans-57.6-33.2-176.5-178.70000112E190 I265 K269 R270E190-V267 HydrophobicContact CB-CG2 4.01Å; E190-V267 HydrophobicContact CG-CG2 4.06Å; I265-V267 PolarHBondContact O-N 3.1Å; V267-K269 VanDerWaalsContact C-N 3.26Å; V267-K269 PolarHBondContact O-N 2.77Å; V267-R270 PolarHBondContact O-N 3.37Å
268Q91.9Very high96.6Very high166 Ų16649.5 Ų49.578%0.77625%0.248SC*.THydrogen-bonded Turntrans-74.6-18.3-178.7-59.8-57.4-55.500112.9D266D266-Q268 PolarHBondContact O-N 2.9Å; D266-Q268 PolarHBondContact OD1-N 2.75Å; D266-Q268 VanDerWaalsContact OD1-N 3.11Å
269K94.8Very high96.6Very high150 Ų15056.1 Ų56.165%0.65228%0.283SS*.THydrogen-bonded Turntrans-105.8-7.9178.7-64.3177.6-173.1153.10112.8D266 V267D266-K269 HydrophobicContact CB-CB 4.28Å; D266-K269 HydrophobicContact CB-CD 4.24Å; D266-K269 HydrophobicContact CB-CG 4.4Å; D266-K269 PolarHBondContact O-N 3.04Å; D266-K269 VanDerWaalsContact OD2-CD 3.27Å; D266-K269 WeakPolarHBondContact OD2-CD 3.32Å; D266-K269 WeakPolarHBondContact OD2-CE 3.28Å; D266-K269 IonicContact OD2-NZ 3.27Å; D266-K269 PolarHBondContact OD2-NZ 2.65Å; D266-K269 VanDerWaalsContact OD2-NZ 3.14Å; V267-K269 VanDerWaalsContact C-N 3.26Å; V267-K269 PolarHBondContact O-N 2.77Å
270R97.5Very high96.5Very high4 Ų457 Ų572%0.01529%0.287CS..SBendtrans-77139.6177.2-165.4-170.9-60.6155.95.6109.5E190 S205 K261 L262 C264 I265 D266 V267 S272E190-R270 IonicContact OE1-CZ 3.96Å; E190-R270 IonicContact OE1-NH1 3.67Å; E190-R270 PolarHBondContact OE1-NH1 2.93Å; E190-R270 IonicContact OE1-NH2 2.86Å; E190-R270 IonicContact OE2-CZ 2.74Å; E190-R270 IonicContact OE2-NH1 2.67Å; E190-R270 PolarHBondContact OE2-NH1 3.35Å; E190-R270 IonicContact OE2-NH2 2.95Å; E190-R270 PolarHBondContact OE2-NH2 3.08Å; S205-R270 PolarHBondContact O-NH1 3.37Å; K261-R270 WeakPolarHBondContact O-CA 3.49Å; K261-R270 WeakPolarHBondContact O-CG 3.43Å; L262-R270 VanDerWaalsContact O-CD 3.28Å; L262-R270 WeakPolarHBondContact O-CD 3.39Å; L262-R270 VanDerWaalsContact O-CG 3.26Å; L262-R270 WeakPolarHBondContact O-CG 3.43Å; C264-R270 HydrophobicContact CB-CB 3.98Å; C264-R270 HydrophobicContact CB-CG 4.24Å; C264-R270 PolarHBondContact O-NE 3.49Å; C264-R270 PolarHBondContact O-NH2 3.3Å; C264-R270 VanDerWaalsContact O-NH2 3.17Å; I265-R270 PolarHBondContact O-NH2 3.34Å; D266-R270 PolarHBondContact O-N 2.81Å; V267-R270 PolarHBondContact O-N 3.37Å; R270-S272 PolarHBondContact O-N 3.2Å
271I97Very high96.5Very high7 Ų758 Ų584%0.03630%0.302CS..  trans-58.5127.9166.3-66.8168.3000108.8W208 L258 K261 L262 E276 L277 L280W208-I271 WeakPolarHBondContact CB-O 3.07Å; W208-I271 HydrophobicContact CD2-CG2 4.35Å; W208-I271 HydrophobicContact CE3-CG2 3.65Å; W208-I271 HydrophobicContact CZ3-CG2 3.85Å; L258-I271 HydrophobicContact CD1-CD1 4.49Å; K261-I271 HydrophobicContact CB-CD1 3.5Å; K261-I271 HydrophobicContact CB-CG1 3.91Å; K261-I271 HydrophobicContact CD-CD1 4Å; K261-I271 HydrophobicContact CD-CG1 4.47Å; K261-I271 HydrophobicContact CG-CD1 4.41Å; K261-I271 PolarHBondContact O-N 3.17Å; L262-I271 HydrophobicContact CD2-CB 4.19Å; L262-I271 HydrophobicContact CD2-CG2 4.31Å; I271-E276 VanDerWaalsContact CA-OE2 3.31Å; I271-E276 WeakPolarHBondContact CA-OE2 3.49Å; I271-E276 HydrophobicContact CG2-CB 4.15Å; I271-L277 HydrophobicContact CD1-CD1 4.17Å; I271-L277 HydrophobicContact CG2-CB 4.15Å; I271-L280 HydrophobicContact CD1-CD1 3.76Å; I271-L280 HydrophobicContact CD1-CD2 4.31Å; I271-L280 HydrophobicContact CD1-CG 4.35Å
272S95.6Very high96.5Very high23 Ų2355.6 Ų55.616%0.16129%0.291CS..  trans-136.3-1.8-170.775.80000113.9R138 W208 R270 E276R138-S272 PolarHBondContact NH1-O 2.84Å; W208-S272 PolarHBondContact NE1-O 2.87Å; R270-S272 PolarHBondContact O-N 3.2Å; S272-E276 PolarHBondContact N-OE2 2.81Å; S272-E276 PolarHBondContact OG-OE1 3.43Å; S272-E276 PolarHBondContact OG-OE2 2.96Å
273C96.9Very high96.4Very high26 Ų2655.8 Ų55.818%0.17629%0.292CS..SBendtrans-151165.5175.171.20000112.6W208 A275 E276 L277W208-C273 VanDerWaalsContact CH2-C 3.4Å; W208-C273 WeakPolarHBondContact CH2-O 3.44Å; W208-C273 VanDerWaalsContact CZ2-CA 3.5Å; C273-A275 VanDerWaalsContact C-N 3.35Å; C273-A275 PolarHBondContact O-N 2.85Å; C273-E276 PolarHBondContact O-N 2.91Å; C273-E276 VanDerWaalsContact SG-CD 3.54Å; C273-E276 VanDerWaalsContact SG-CG 3.54Å; C273-L277 PolarHBondContact O-N 3.07Å
274L98Very high96.4Very high34 Ų3460.3 Ų60.318%0.17832%0.324CS..Hα-helixtrans-61.3-41.4-178.8179.763.2000112.3A131 L132 W208 E276 L277 Q278 W288A131-L274 HydrophobicContact CB-CD1 4.02Å; L132-L274 HydrophobicContact CD2-CD1 4.4Å; L132-L274 HydrophobicContact CD2-CD2 3.87Å; W208-L274 HydrophobicContact CH2-CB 4.43Å; L274-E276 PolarHBondContact O-N 3.32Å; L274-L277 WeakPolarHBondContact O-CB 3.4Å; L274-L277 PolarHBondContact O-N 3.25Å; L274-L277 VanDerWaalsContact O-N 3.13Å; L274-Q278 HydrophobicContact CD1-CG 4.19Å; L274-Q278 HydrophobicContact CG-CG 4.24Å; L274-Q278 VanDerWaalsContact O-CG 3.31Å; L274-Q278 WeakPolarHBondContact O-CG 3.33Å; L274-Q278 PolarHBondContact O-N 3.42Å; L274-W288 HydrophobicContact CD1-CE3 4.26Å; L274-W288 HydrophobicContact CD1-CH2 4.14Å; L274-W288 HydrophobicContact CD1-CZ3 3.75Å
275A97.9Very high96.3Very high64 Ų6464.4 Ų64.453%0.52934%0.344SS..Hα-helixtrans-60.4-43.3-179.600000112.3C273 L277 Q278 D279C273-A275 VanDerWaalsContact C-N 3.35Å; C273-A275 PolarHBondContact O-N 2.85Å; A275-L277 VanDerWaalsContact C-N 3.29Å; A275-L277 PolarHBondContact O-N 3Å; A275-Q278 PolarHBondContact O-N 2.9Å; A275-D279 WeakPolarHBondContact O-CB 3.16Å; A275-D279 PolarHBondContact O-N 3.25Å
276E98Very high96.5Very high79 Ų7962.9 Ų62.937%0.36934%0.338SS..Hα-helixtrans-63.9-32.7176.4-73.8165.2-159.600113I271 S272 C273 L274I271-E276 VanDerWaalsContact CA-OE2 3.31Å; I271-E276 WeakPolarHBondContact CA-OE2 3.49Å; I271-E276 HydrophobicContact CG2-CB 4.15Å; S272-E276 PolarHBondContact N-OE2 2.81Å; S272-E276 PolarHBondContact OG-OE1 3.43Å; S272-E276 PolarHBondContact OG-OE2 2.96Å; C273-E276 PolarHBondContact O-N 2.91Å; C273-E276 VanDerWaalsContact SG-CD 3.54Å; C273-E276 VanDerWaalsContact SG-CG 3.54Å; L274-E276 PolarHBondContact O-N 3.32Å
277L98.3Very high96.7Very high0 Ų064 Ų640%034%0.343CS..Hα-helixtrans-71.8-42.9174.4-173.873.5000111I127 A131 W208 L258 I271 C273 L274 A275 D279 L280 M283 W288I127-L277 HydrophobicContact CG2-CD1 4.39Å; I127-L277 HydrophobicContact CG2-CD2 4.06Å; A131-L277 HydrophobicContact CB-CD2 3.32Å; W208-L277 HydrophobicContact CH2-CB 4.42Å; W208-L277 HydrophobicContact CZ3-CB 4.03Å; W208-L277 HydrophobicContact CZ3-CD2 4.02Å; W208-L277 HydrophobicContact CZ3-CG 4.46Å; L258-L277 HydrophobicContact CD1-CD1 3.51Å; I271-L277 HydrophobicContact CD1-CD1 4.17Å; I271-L277 HydrophobicContact CG2-CB 4.15Å; C273-L277 PolarHBondContact O-N 3.07Å; L274-L277 WeakPolarHBondContact O-CB 3.4Å; L274-L277 PolarHBondContact O-N 3.25Å; L274-L277 VanDerWaalsContact O-N 3.13Å; A275-L277 VanDerWaalsContact C-N 3.29Å; A275-L277 PolarHBondContact O-N 3Å; L277-D279 VanDerWaalsContact C-N 3.27Å; L277-D279 PolarHBondContact O-N 3.28Å; L277-L280 HydrophobicContact CD1-CD1 3.96Å; L277-L280 WeakPolarHBondContact O-CB 3.21Å; L277-L280 VanDerWaalsContact O-CG 3.32Å; L277-L280 WeakPolarHBondContact O-CG 3.09Å; L277-L280 PolarHBondContact O-N 3.25Å; L277-M283 HydrophobicContact CD1-CE 3.92Å; L277-M283 HydrophobicContact CG-CE 4.22Å; L277-M283 HydrophobicContact CG-CG 4.48Å; L277-M283 WeakPolarHBondContact O-CG 3.37Å; L277-W288 HydrophobicContact CD2-CH2 3.83Å; L277-W288 HydrophobicContact CG-CH2 4.42Å
278Q98.1Very high97Very high75 Ų7564.3 Ų64.335%0.3534%0.342SS..Hα-helixtrans-63-33.2179.7-74178.5-39.100112.7L274 A275 L280 W288L274-Q278 HydrophobicContact CD1-CG 4.19Å; L274-Q278 HydrophobicContact CG-CG 4.24Å; L274-Q278 VanDerWaalsContact O-CG 3.31Å; L274-Q278 WeakPolarHBondContact O-CG 3.33Å; L274-Q278 PolarHBondContact O-N 3.42Å; A275-Q278 PolarHBondContact O-N 2.9Å; Q278-L280 PolarHBondContact O-N 3.32Å; Q278-W288 HydrophobicContact CB-CZ2 4.45Å; Q278-W288 HydrophobicContact CG-CD2 3.97Å; Q278-W288 VanDerWaalsContact CG-CE2 3.48Å; Q278-W288 HydrophobicContact CG-CG 4.46Å; Q278-W288 HydrophobicContact CG-CH2 4.17Å; Q278-W288 HydrophobicContact CG-CZ2 3.59Å
279D97.6Very high97.3Very high141 Ų14161.8 Ų61.875%0.75433%0.334SS*.THydrogen-bonded Turntrans-73.8-6-180-165.759.5000113.9A275 L277A275-D279 WeakPolarHBondContact O-CB 3.16Å; A275-D279 PolarHBondContact O-N 3.25Å; L277-D279 VanDerWaalsContact C-N 3.27Å; L277-D279 PolarHBondContact O-N 3.28Å
280L97.6Very high97.5Very high17 Ų1755 Ų559%0.08931%0.305CS..SBendtrans-71.6136.4176.1-60.2-178000111.5L258 K261 I271 L277 Q278 Y282 M283L258-L280 HydrophobicContact CD1-CD1 3.59Å; K261-L280 HydrophobicContact CD-CD2 3.53Å; I271-L280 HydrophobicContact CD1-CD1 3.76Å; I271-L280 HydrophobicContact CD1-CD2 4.31Å; I271-L280 HydrophobicContact CD1-CG 4.35Å; L277-L280 HydrophobicContact CD1-CD1 3.96Å; L277-L280 WeakPolarHBondContact O-CB 3.21Å; L277-L280 VanDerWaalsContact O-CG 3.32Å; L277-L280 WeakPolarHBondContact O-CG 3.09Å; L277-L280 PolarHBondContact O-N 3.25Å; Q278-L280 PolarHBondContact O-N 3.32Å; L280-Y282 PolarHBondContact O-N 3.28Å; L280-M283 HydrophobicContact CB-CG 4.15Å; L280-M283 WeakPolarHBondContact O-CA 3.45Å; L280-M283 PolarHBondContact O-N 2.75Å
281D97Very high97.5Very high148 Ų14854.8 Ų54.879%0.79130%0.304SS*.G310 helixtrans-51.1-36.8172-64-28.5000112.6M283 S284D281-M283 PolarHBondContact O-N 3.06Å; D281-S284 VanDerWaalsContact O-CB 3.29Å; D281-S284 WeakPolarHBondContact O-CB 3.39Å; D281-S284 PolarHBondContact O-N 3.49Å; D281-S284 VanDerWaalsContact O-N 3.15Å; D281-S284 PolarHBondContact O-OG 3.5Å
282Y97.5Very high97.6Very high43 Ų4357.2 Ų57.217%0.16932%0.317CS..G310 helixtrans-65.7-16.9178.1-173.7-136000114K124 E254 M255 L258 L280 D285K124-Y282 HydrophobicContact CB-CE1 4.48Å; K124-Y282 HydrophobicContact CD-CE1 3.91Å; K124-Y282 HydrophobicContact CD-CE2 4.07Å; K124-Y282 WeakPolarHBondContact CE-O 3.27Å; K124-Y282 HydrophobicContact CG-CE1 3.92Å; K124-Y282 PolarHBondContact NZ-O 3.26Å; E254-Y282 HydrophobicContact CB-CD1 4.24Å; E254-Y282 HydrophobicContact CB-CD2 3.26Å; E254-Y282 HydrophobicContact CB-CE2 3.6Å; E254-Y282 HydrophobicContact CB-CG 3.61Å; E254-Y282 HydrophobicContact CG-CD2 3.86Å; E254-Y282 HydrophobicContact CG-CE2 4.36Å; E254-Y282 HydrophobicContact CG-CG 4.45Å; M255-Y282 HydrophobicContact CE-CE1 4.33Å; L258-Y282 HydrophobicContact CB-CD1 4.21Å; L258-Y282 HydrophobicContact CD2-CD1 3.93Å; L258-Y282 HydrophobicContact CD2-CE1 3.92Å; L280-Y282 PolarHBondContact O-N 3.28Å; Y282-D285 VanDerWaalsContact O-OD1 3.09Å
283M97.7Very high97.7Very high3 Ų361 Ų612%0.01534%0.336CS..G310 helixtrans-100.71.9177.6-59.7-56174.400113.1L258 L277 L280 D281 D285 V286 W288L258-M283 HydrophobicContact CD1-CE 3.95Å; L258-M283 HydrophobicContact CD2-CE 3.58Å; L258-M283 HydrophobicContact CG-CE 4.4Å; L277-M283 HydrophobicContact CD1-CE 3.92Å; L277-M283 HydrophobicContact CG-CE 4.22Å; L277-M283 HydrophobicContact CG-CG 4.48Å; L277-M283 WeakPolarHBondContact O-CG 3.37Å; L280-M283 HydrophobicContact CB-CG 4.15Å; L280-M283 WeakPolarHBondContact O-CA 3.45Å; L280-M283 PolarHBondContact O-N 2.75Å; D281-M283 PolarHBondContact O-N 3.06Å; M283-D285 PolarHBondContact O-N 3.08Å; M283-V286 HydrophobicContact CB-CG2 4.43Å; M283-V286 WeakPolarHBondContact O-CB 3.41Å; M283-V286 PolarHBondContact O-N 2.84Å; M283-V286 HydrophobicContact SD-CG2 4.02Å; M283-W288 HydrophobicContact CB-CZ2 4.18Å; M283-W288 HydrophobicContact CG-CZ2 4.26Å; M283-W288 HydrophobicContact SD-CZ2 4.48Å
284S96.4Very high97.7Very high106 Ų10662.8 Ų62.874%0.74134%0.34SS*.THydrogen-bonded Turntrans-62.4-24.9-177.959.20000114.2D281D281-S284 VanDerWaalsContact O-CB 3.29Å; D281-S284 WeakPolarHBondContact O-CB 3.39Å; D281-S284 PolarHBondContact O-N 3.49Å; D281-S284 VanDerWaalsContact O-N 3.15Å; D281-S284 PolarHBondContact O-OG 3.5Å
285D95.9Very high97.7Very high115 Ų11567.4 Ų67.462%0.61536%0.361SS*.THydrogen-bonded Turntrans-88.3-4.3176.964.5-38.4000113.6K124 Y282 M283K124-D285 IonicContact NZ-OD1 3.71Å; K124-D285 PolarHBondContact NZ-OD1 3.08Å; K124-D285 IonicContact NZ-OD2 3.47Å; K124-D285 PolarHBondContact NZ-OD2 3.23Å; Y282-D285 VanDerWaalsContact O-OD1 3.09Å; M283-D285 PolarHBondContact O-N 3.08Å
286V97.6Very high97.5Very high23 Ų2367.5 Ų67.514%0.13935%0.352CS..  trans-87.7117.1-175.3-179.40000110.6M283 W288 V291M283-V286 HydrophobicContact CB-CG2 4.43Å; M283-V286 WeakPolarHBondContact O-CB 3.41Å; M283-V286 PolarHBondContact O-N 2.84Å; M283-V286 HydrophobicContact SD-CG2 4.02Å; V286-W288 HydrophobicContact CG1-CD2 4.01Å; V286-W288 HydrophobicContact CG1-CG 4.27Å; V286-W288 HydrophobicContact CG1-CZ2 4.21Å; V286-W288 VanDerWaalsContact O-CD1 3.27Å; V286-W288 PolarHBondContact O-N 2.69Å; V286-V291 HydrophobicContact CG1-CG2 3.77Å
287N97.9Very high97.2Very high89 Ų8968.8 Ų68.848%0.47637%0.367SS..  trans-81.199.1166.1-177.8-22.6000109.9D289 A290 V291N287-D289 PolarHBondContact O-N 3.35Å; N287-D289 PolarHBondContact OD1-N 2.76Å; N287-A290 HydrophobicContact CB-CB 3.86Å; N287-A290 WeakPolarHBondContact O-CB 3.34Å; N287-A290 PolarHBondContact O-N 2.92Å; N287-A290 PolarHBondContact OD1-N 2.75Å; N287-V291 WeakPolarHBondContact O-CG2 3.44Å; N287-V291 PolarHBondContact O-N 2.94Å
288W98.2Very high96.8Very high37 Ų3769 Ų6914%0.1437%0.369CS..Hα-helixtrans-66.1-31.6-175.5-68.691.6000114.3C128 L132 L274 L277 Q278 M283 V286 V291 L292C128-W288 HydrophobicContact CB-CH2 4Å; C128-W288 HydrophobicContact CB-CZ3 3.83Å; L132-W288 HydrophobicContact CD1-CE3 4.29Å; L132-W288 HydrophobicContact CD2-CE3 4.09Å; L132-W288 HydrophobicContact CG-CE3 4.07Å; L132-W288 HydrophobicContact CG-CZ3 4.23Å; L274-W288 HydrophobicContact CD1-CE3 4.26Å; L274-W288 HydrophobicContact CD1-CH2 4.14Å; L274-W288 HydrophobicContact CD1-CZ3 3.75Å; L277-W288 HydrophobicContact CD2-CH2 3.83Å; L277-W288 HydrophobicContact CG-CH2 4.42Å; Q278-W288 HydrophobicContact CB-CZ2 4.45Å; Q278-W288 HydrophobicContact CG-CD2 3.97Å; Q278-W288 VanDerWaalsContact CG-CE2 3.48Å; Q278-W288 HydrophobicContact CG-CG 4.46Å; Q278-W288 HydrophobicContact CG-CH2 4.17Å; Q278-W288 HydrophobicContact CG-CZ2 3.59Å; M283-W288 HydrophobicContact CB-CZ2 4.18Å; M283-W288 HydrophobicContact CG-CZ2 4.26Å; M283-W288 HydrophobicContact SD-CZ2 4.48Å; V286-W288 HydrophobicContact CG1-CD2 4.01Å; V286-W288 HydrophobicContact CG1-CG 4.27Å; V286-W288 HydrophobicContact CG1-CZ2 4.21Å; V286-W288 VanDerWaalsContact O-CD1 3.27Å; V286-W288 PolarHBondContact O-N 2.69Å; W288-V291 PolarHBondContact O-N 3.41Å; W288-L292 WeakPolarHBondContact O-CB 3.38Å; W288-L292 PolarHBondContact O-N 3.41Å
289D98.2Very high96.4Very high114 Ų11468.5 Ų68.561%0.6138%0.384SS*.Hα-helixtrans-68.3-39.7173.5-67.3-48.3000110.8N287 V291 L292 N293N287-D289 PolarHBondContact O-N 3.35Å; N287-D289 PolarHBondContact OD1-N 2.76Å; D289-V291 VanDerWaalsContact C-N 3.33Å; D289-L292 PolarHBondContact O-N 3.09Å; D289-N293 WeakPolarHBondContact O-CB 3.37Å; D289-N293 PolarHBondContact O-N 3Å; D289-N293 PolarHBondContact O-ND2 2.85Å
290A98.3Very high96.2Very high6 Ų663.9 Ų63.95%0.0536%0.357CS..Hα-helixtrans-65.3-37.417400000111.6N287 K294 Q295 L296N287-A290 HydrophobicContact CB-CB 3.86Å; N287-A290 WeakPolarHBondContact O-CB 3.34Å; N287-A290 PolarHBondContact O-N 2.92Å; N287-A290 PolarHBondContact OD1-N 2.75Å; A290-K294 PolarHBondContact O-N 3.34Å; A290-Q295 HydrophobicContact CB-CB 4.1Å; A290-Q295 WeakPolarHBondContact O-CB 3.42Å; A290-Q295 PolarHBondContact O-N 3.46Å; A290-L296 HydrophobicContact CB-CD2 4.11Å; A290-L296 HydrophobicContact CB-CG 4.06Å
291V98.4Very high95.9Very high1 Ų167.9 Ų67.91%0.00638%0.378CS..Hα-helixtrans-61.5-55.8171.2-179.30000109.4F82 L125 C128 E129 L132 V286 N287 W288 D289 N293 K294 L296F82-V291 HydrophobicContact CE2-CG1 4.16Å; F82-V291 HydrophobicContact CZ-CG1 4.12Å; F82-V291 WeakPolarHBondContact CZ-O 3.49Å; L125-V291 HydrophobicContact CD1-CG1 4.24Å; L125-V291 HydrophobicContact CD1-CG2 4Å; C128-V291 HydrophobicContact CB-CG1 4.15Å; C128-V291 HydrophobicContact CB-CG2 4.35Å; E129-V291 HydrophobicContact CG-CG1 3.78Å; L132-V291 HydrophobicContact CD1-CB 4.05Å; L132-V291 HydrophobicContact CD1-CG1 3.58Å; V286-V291 HydrophobicContact CG1-CG2 3.77Å; N287-V291 WeakPolarHBondContact O-CG2 3.44Å; N287-V291 PolarHBondContact O-N 2.94Å; W288-V291 PolarHBondContact O-N 3.41Å; D289-V291 VanDerWaalsContact C-N 3.33Å; V291-N293 PolarHBondContact O-N 3.37Å; V291-N293 VanDerWaalsContact O-N 3.14Å; V291-K294 WeakPolarHBondContact O-CA 3.5Å; V291-K294 PolarHBondContact O-N 3.03Å; V291-L296 HydrophobicContact CG2-CD1 3.76Å
292L98.4Very high95.5Very high58 Ų5861.1 Ų61.130%0.30434%0.342SS..Hα-helixtrans-54.8-38.1-177.2-176.963.2000112.8P81 L132 W288 D289 K294P81-L292 HydrophobicContact CG-CD1 4.07Å; L132-L292 HydrophobicContact CD1-CB 4.14Å; L132-L292 HydrophobicContact CD1-CD1 4.37Å; W288-L292 WeakPolarHBondContact O-CB 3.38Å; W288-L292 PolarHBondContact O-N 3.41Å; D289-L292 PolarHBondContact O-N 3.09Å; L292-K294 VanDerWaalsContact C-N 3.28Å; L292-K294 PolarHBondContact O-N 3Å
293N98Very high95Very high102 Ų10263 Ų6355%0.54536%0.355SS..THydrogen-bonded Turntrans-85.69178-66.9-59.3000114D289 V291 Q295D289-N293 WeakPolarHBondContact O-CB 3.37Å; D289-N293 PolarHBondContact O-N 3Å; D289-N293 PolarHBondContact O-ND2 2.85Å; V291-N293 PolarHBondContact O-N 3.37Å; V291-N293 VanDerWaalsContact O-N 3.14Å; N293-Q295 HydrophobicContact CB-CG 3.97Å; N293-Q295 PolarHBondContact O-N 3.2Å
294K97.8Very high94.1Very high63 Ų6370.7 Ų70.727%0.27438%0.384SS..THydrogen-bonded Turntrans54.436.1-179.8-64.9-176.2174.6-172.90113.9P81 F82 D155 H159 H161 A290 V291 L292P81-K294 VanDerWaalsContact O-CE 3.22Å; P81-K294 WeakPolarHBondContact O-CE 3.48Å; P81-K294 PolarHBondContact O-NZ 3.43Å; F82-K294 HydrophobicContact CE1-CD 4.35Å; F82-K294 HydrophobicContact CE1-CG 3.78Å; F82-K294 HydrophobicContact CZ-CG 3.97Å; D155-K294 IonicContact OD2-NZ 3.41Å; D155-K294 PolarHBondContact OD2-NZ 3.44Å; H159-K294 HydrophobicContact CB-CD 4.39Å; H161-K294 PolarHBondContact CE1-NZ 3.34Å; H161-K294 PolarHBondContact NE2-NZ 3.4Å; A290-K294 PolarHBondContact O-N 3.34Å; V291-K294 WeakPolarHBondContact O-CA 3.5Å; V291-K294 PolarHBondContact O-N 3.03Å; L292-K294 VanDerWaalsContact C-N 3.28Å; L292-K294 PolarHBondContact O-N 3Å
295Q97.3Very high92.8Very high132 Ų13276.9 Ų76.962%0.61739%0.391SS*.  trans-87.1-16.3-179.4-64.6178-11.800112.8A290 N293 P297A290-Q295 HydrophobicContact CB-CB 4.1Å; A290-Q295 WeakPolarHBondContact O-CB 3.42Å; A290-Q295 PolarHBondContact O-N 3.46Å; N293-Q295 HydrophobicContact CB-CG 3.97Å; N293-Q295 PolarHBondContact O-N 3.2Å; Q295-P297 WeakPolarHBondContact O-CD 3Å
296L94.4Very high91.7Very high65 Ų6580.4 Ų80.434%0.3440%0.395SS..SBendtrans-95.1107.9176.4-57-172.5000109.6L125 H159 A290 V291 P298L125-L296 HydrophobicContact CD1-CB 4.23Å; L125-L296 HydrophobicContact CD1-CD1 4.42Å; L125-L296 HydrophobicContact CD2-CB 4.32Å; L125-L296 WeakPolarHBondContact CD2-O 3.26Å; H159-L296 PolarHBondContact CE1-O 3Å; H159-L296 VanDerWaalsContact CE1-O 3.26Å; A290-L296 HydrophobicContact CB-CD2 4.11Å; A290-L296 HydrophobicContact CB-CG 4.06Å; V291-L296 HydrophobicContact CG2-CD1 3.76Å; L296-P298 WeakPolarHBondContact O-CD 3.43Å
297P90.1Very high90.5Very high106 Ų10681.5 Ų81.569%0.68840%0.4SS*.  trans-72.3130.7-178.128.3-33.6000110.8Q295Q295-P297 WeakPolarHBondContact O-CD 3Å
298P91.3Very high89.6Confident5 Ų577.9 Ų77.93%0.03238%0.381CS..  trans-64.5145173.5-24.637.2000112.4L125 Y126 G158 L296 F300L125-P298 HydrophobicContact CD2-CB 4.1Å; L125-P298 HydrophobicContact CD2-CG 3.75Å; Y126-P298 HydrophobicContact CE1-CB 3.88Å; Y126-P298 HydrophobicContact CE1-CG 4.28Å; G158-P298 WeakPolarHBondContact O-CG 3.42Å; L296-P298 WeakPolarHBondContact O-CD 3.43Å; P298-F300 PolarHBondContact O-N 3.11Å; P298-F300 VanDerWaalsContact O-N 3.15Å
299G89.8Confident88.4Confident65 Ų6576.7 Ų76.767%0.6738%0.378SS*.SBendtrans-67.8-12.4-179.400000114.8
300F93.1Very high87.1Confident44 Ų4474.5 Ų74.519%0.19337%0.367CS..  trans-114.1123.9175175.4-98.9000109.8H111 V116 F118 T122 L154 P298 P302H111-F300 AromaticContact CE1-CE1 3.85Å; H111-F300 AromaticContact CE1-CZ 3.8Å; H111-F300 AromaticContact ND1-CE1 3.75Å; H111-F300 AromaticContact ND1-CZ 3.43Å; H111-F300 WeakPolarHBondContact ND1-CZ 3.28Å; V116-F300 HydrophobicContact CG1-CD2 3.83Å; V116-F300 HydrophobicContact CG1-CE2 3.52Å; V116-F300 HydrophobicContact CG1-CZ 4.01Å; V116-F300 HydrophobicContact CG2-CE2 4.14Å; V116-F300 HydrophobicContact CG2-CZ 4.23Å; F118-F300 HydrophobicContact CD1-CB 4.1Å; F118-F300 HydrophobicContact CD1-CD1 4.46Å; F118-F300 HydrophobicContact CD1-CG 4.2Å; F118-F300 HydrophobicContact CE1-CB 4.1Å; F118-F300 AromaticContact CE1-CD1 3.63Å; F118-F300 HydrophobicContact CE1-CD1 3.63Å; F118-F300 HydrophobicContact CE1-CD2 4.35Å; F118-F300 HydrophobicContact CE1-CE1 4.09Å; F118-F300 AromaticContact CE1-CG 3.75Å; F118-F300 HydrophobicContact CE1-CG 3.75Å; F118-F300 HydrophobicContact CZ-CD1 4.45Å; F118-F300 HydrophobicContact CZ-CE1 4.5Å; T122-F300 HydrophobicContact CG2-CB 4.04Å; L154-F300 HydrophobicContact CD1-CD1 3.95Å; L154-F300 HydrophobicContact CD1-CE1 3.74Å; P298-F300 PolarHBondContact O-N 3.11Å; P298-F300 VanDerWaalsContact O-N 3.15Å; F300-P302 HydrophobicContact CE1-CG 4.02Å
301I91.6Very high85.6Confident101 Ų10177.8 Ų77.852%0.51839%0.387SS..  trans-117.1120.2177.1-58176.6000108.3
302P88.4Confident84.1Confident5 Ų581 Ų813%0.03241%0.407CS..  trans-58.9151.5176.8-25.234.3000113.1L154 F300 R304L154-P302 HydrophobicContact CB-CG 3.81Å; L154-P302 HydrophobicContact CD1-CG 3.67Å; L154-P302 HydrophobicContact CG-CG 4.38Å; F300-P302 HydrophobicContact CE1-CG 4.02Å; P302-R304 PolarHBondContact O-N 2.91Å; P302-R304 VanDerWaalsContact O-N 3.15Å
303N85.4Confident82.6Confident84 Ų8480.8 Ų80.845%0.44940%0.404SS..  trans-70115.5178.1-169.8-28.5000110.6R305 R306 N308N303-R305 VanDerWaalsContact C-N 3.27Å; N303-R305 PolarHBondContact O-N 3.39Å; N303-R305 WeakPolarHBondContact OD1-CB 3.46Å; N303-R305 PolarHBondContact OD1-N 3.2Å; N303-R306 VanDerWaalsContact O-O 3.07Å; N303-N308 PolarHBondContact O-ND2 3.43Å; N303-N308 VanDerWaalsContact O-ND2 3.17Å
304R80Confident80.9Confident163 Ų16378.1 Ų78.162%0.61539%0.388SS*.THydrogen-bonded Turntrans-70.6-17-179.4-64.6-177.7172.6-165.4-7.1114.5E156 H157 P302E156-R304 PolarHBondContact O-NE 3.23Å; E156-R304 VanDerWaalsContact O-NE 3.08Å; E156-R304 PolarHBondContact O-NH2 2.98Å; H157-R304 PolarHBondContact CD2-NH2 3.04Å; H157-R304 VanDerWaalsContact CD2-NH2 3.31Å; H157-R304 PolarHBondContact NE2-NH2 2.56Å; P302-R304 PolarHBondContact O-N 2.91Å; P302-R304 VanDerWaalsContact O-N 3.15Å
305R69.6Low78.9Confident237 Ų23779.7 Ų79.789%0.89440%0.399SS*.THydrogen-bonded Turntrans-88.2-9.1-176.2-61.4-175.4-179.1179.11.3113.3N303N303-R305 VanDerWaalsContact C-N 3.27Å; N303-R305 PolarHBondContact O-N 3.39Å; N303-R305 WeakPolarHBondContact OD1-CB 3.46Å; N303-R305 PolarHBondContact OD1-N 3.2Å
306R72.3Confident77.1Confident188 Ų18876.4 Ų76.471%0.70938%0.384SS*.SBendtrans-128.8147.1-178.8-66.5-173177.9-168.7-0.4109.2N303 N308N303-R306 VanDerWaalsContact O-O 3.07Å; R306-N308 PolarHBondContact O-N 3.45Å; R306-N308 PolarHBondContact O-ND2 3.34Å
307L72.3Confident75.4Confident47 Ų4775.1 Ų75.125%0.24638%0.376CS..  trans-70.7122.3163.5-102.3133.6000108R27 I29 I39 C309R27-L307 VanDerWaalsContact CD-CD1 3.4Å; I29-L307 HydrophobicContact CB-CD2 4.45Å; I29-L307 HydrophobicContact CG2-CD2 3.54Å; I39-L307 HydrophobicContact CD1-CD2 4.26Å; L307-C309 PolarHBondContact O-N 3.36Å; L307-C309 VanDerWaalsContact O-N 3.11Å
308N78.5Confident73.7Confident12 Ų1277.5 Ų77.56%0.06438%0.38CS..  trans-87.347.3-179.4-57.7-66.2000110L104 G105 G106 Y110 N303 R306L104-N308 PolarHBondContact O-ND2 3.22Å; G105-N308 VanDerWaalsContact O-CB 3.29Å; G105-N308 WeakPolarHBondContact O-CB 3.19Å; G106-N308 VanDerWaalsContact CA-O 3.27Å; G106-N308 WeakPolarHBondContact CA-O 3.43Å; Y110-N308 HydrophobicContact CD1-CB 4.05Å; Y110-N308 WeakPolarHBondContact CD1-O 3.43Å; Y110-N308 HydrophobicContact CE1-CB 3.91Å; N303-N308 PolarHBondContact O-ND2 3.43Å; N303-N308 VanDerWaalsContact O-ND2 3.17Å; R306-N308 PolarHBondContact O-N 3.45Å; R306-N308 PolarHBondContact O-ND2 3.34Å
309C74.1Confident72Confident13 Ų1383.5 Ų83.59%0.08841%0.41CS..SBendtrans-130.2170.9177.168.70000109.8L307 P311L307-C309 PolarHBondContact O-N 3.36Å; L307-C309 VanDerWaalsContact O-N 3.11Å; C309-P311 WeakPolarHBondContact O-CD 3.06Å
310D70.6Confident70.2Confident68 Ų6886.2 Ų86.236%0.36441%0.408SS..  trans-63.4119.2177.5-168.6-32.7000110.5T312 F313D310-T312 PolarHBondContact O-N 2.91Å; D310-T312 VanDerWaalsContact O-N 3.17Å; D310-T312 VanDerWaalsContact OD1-CB 3.28Å; D310-T312 WeakPolarHBondContact OD1-CB 3.24Å; D310-T312 VanDerWaalsContact OD1-CG2 3.26Å; D310-T312 WeakPolarHBondContact OD1-CG2 3.2Å; D310-T312 PolarHBondContact OD1-N 3.47Å; D310-T312 PolarHBondContact OD1-OG1 3.16Å; D310-T312 PolarHBondContact OD2-OG1 3.43Å; D310-F313 HydrophobicContact CB-CD2 3.86Å; D310-F313 HydrophobicContact CB-CE2 3.6Å; D310-F313 HydrophobicContact CB-CZ 4.23Å; D310-F313 VanDerWaalsContact O-CD2 3.24Å; D310-F313 WeakPolarHBondContact O-CD2 3.29Å; D310-F313 PolarHBondContact O-N 3.05Å
311P65.6Low68.2Low75 Ų7586.9 Ų86.949%0.48741%0.412SS..THydrogen-bonded Turntrans-66.2-15.1-178.826.8-34.2000113.2C309 F313 E314 L315C309-P311 WeakPolarHBondContact O-CD 3.06Å; P311-F313 PolarHBondContact O-N 3.11Å; P311-E314 PolarHBondContact O-N 2.74Å; P311-L315 WeakPolarHBondContact O-CD1 3.38Å; P311-L315 PolarHBondContact O-N 3.42Å
312T66.8Low65.7Low68 Ų6887.8 Ų87.842%0.41743%0.427SS..Hα-helixtrans-62.3-26.2175.459.30000112.5D310 E314 L315 E316D310-T312 PolarHBondContact O-N 2.91Å; D310-T312 VanDerWaalsContact O-N 3.17Å; D310-T312 VanDerWaalsContact OD1-CB 3.28Å; D310-T312 WeakPolarHBondContact OD1-CB 3.24Å; D310-T312 VanDerWaalsContact OD1-CG2 3.26Å; D310-T312 WeakPolarHBondContact OD1-CG2 3.2Å; D310-T312 PolarHBondContact OD1-N 3.47Å; D310-T312 PolarHBondContact OD1-OG1 3.16Å; D310-T312 PolarHBondContact OD2-OG1 3.43Å; T312-E314 PolarHBondContact O-N 3.41Å; T312-L315 PolarHBondContact O-N 3.4Å; T312-E316 WeakPolarHBondContact O-CB 3.33Å; T312-E316 WeakPolarHBondContact O-CG 3.38Å; T312-E316 PolarHBondContact O-N 3.45Å
313F67.6Low63.7Low53 Ų5394.5 Ų94.523%0.23246%0.456CS..Hα-helixtrans-65.5-38.4176.2-60.4-47.5000112.6I29 K31 D310 P311 E317I29-F313 WeakPolarHBondContact O-CD2 3.35Å; K31-F313 HydrophobicContact CB-CD1 3.92Å; K31-F313 HydrophobicContact CB-CE1 3.6Å; D310-F313 HydrophobicContact CB-CD2 3.86Å; D310-F313 HydrophobicContact CB-CE2 3.6Å; D310-F313 HydrophobicContact CB-CZ 4.23Å; D310-F313 VanDerWaalsContact O-CD2 3.24Å; D310-F313 WeakPolarHBondContact O-CD2 3.29Å; D310-F313 PolarHBondContact O-N 3.05Å; P311-F313 PolarHBondContact O-N 3.11Å; F313-E317 PolarHBondContact O-N 3Å
314E61.5Low61.8Low47 Ų4795.1 Ų95.122%0.2247%0.465CS..Hα-helixtrans-70.1-41.9174.6-67.1-175.7-161.100111R27 P311 T312 E317 M318R27-E314 VanDerWaalsContact CD-OE1 3.26Å; R27-E314 WeakPolarHBondContact CD-OE1 3.22Å; R27-E314 HydrophobicContact CG-CG 4.13Å; R27-E314 IonicContact CZ-OE1 3.58Å; R27-E314 IonicContact CZ-OE2 2.66Å; R27-E314 IonicContact NE-OE1 3.75Å; R27-E314 VanDerWaalsContact NH1-CD 3.26Å; R27-E314 IonicContact NH1-OE1 2.64Å; R27-E314 PolarHBondContact NH1-OE1 3.02Å; R27-E314 IonicContact NH1-OE2 3.77Å; R27-E314 PolarHBondContact NH1-OE2 2.93Å; P311-E314 PolarHBondContact O-N 2.74Å; T312-E314 PolarHBondContact O-N 3.41Å; E314-E317 WeakPolarHBondContact O-CB 3.23Å; E314-E317 PolarHBondContact O-N 2.97Å; E314-M318 WeakPolarHBondContact O-CG 3.23Å; E314-M318 PolarHBondContact O-N 3.48Å
315L57.2Low60.5Low96 Ų9690.1 Ų90.150%0.50345%0.45SS..Hα-helixtrans-65.2-43.2177.9-93.384.5000112.3P311 T312 E317 M318 I319P311-L315 WeakPolarHBondContact O-CD1 3.38Å; P311-L315 PolarHBondContact O-N 3.42Å; T312-L315 PolarHBondContact O-N 3.4Å; L315-E317 PolarHBondContact O-N 3.14Å; L315-M318 PolarHBondContact O-N 3.36Å; L315-I319 HydrophobicContact CB-CD1 4.26Å; L315-I319 HydrophobicContact CD2-CD1 4.41Å; L315-I319 WeakPolarHBondContact O-CB 3.14Å; L315-I319 WeakPolarHBondContact O-CD1 3.37Å; L315-I319 WeakPolarHBondContact O-CG1 3.32Å; L315-I319 PolarHBondContact O-N 2.94Å
316E59.9Low59.5Low63 Ų6385.6 Ų85.629%0.29444%0.439SS..Hα-helixtrans-56.8-41175-82.1-167.1177.200110.6K31 T312 L320K31-E316 VanDerWaalsContact NZ-CD 3.32Å; K31-E316 IonicContact NZ-OE1 3.22Å; K31-E316 PolarHBondContact NZ-OE1 2.88Å; K31-E316 IonicContact NZ-OE2 2.7Å; K31-E316 PolarHBondContact NZ-OE2 3.45Å; T312-E316 WeakPolarHBondContact O-CB 3.33Å; T312-E316 WeakPolarHBondContact O-CG 3.38Å; T312-E316 PolarHBondContact O-N 3.45Å; E316-L320 HydrophobicContact CB-CD1 4.11Å; E316-L320 HydrophobicContact CG-CD1 4.32Å; E316-L320 WeakPolarHBondContact O-CB 3.41Å; E316-L320 PolarHBondContact O-N 2.86Å
317E57.1Low58.1Low38 Ų3883.9 Ų83.918%0.17844%0.437CS..Hα-helixtrans-64.2-48.6176-170.4176.3-172.300111.7A28 F313 E314 L315 I319 E321A28-E317 HydrophobicContact CB-CB 4.48Å; A28-E317 WeakPolarHBondContact CB-OE2 3.27Å; A28-E317 PolarHBondContact N-OE2 3.09Å; F313-E317 PolarHBondContact O-N 3Å; E314-E317 WeakPolarHBondContact O-CB 3.23Å; E314-E317 PolarHBondContact O-N 2.97Å; L315-E317 PolarHBondContact O-N 3.14Å; E317-I319 VanDerWaalsContact C-N 3.3Å; E317-I319 PolarHBondContact O-N 3.49Å; E317-E321 PolarHBondContact O-N 2.88Å; E317-E321 VanDerWaalsContact O-N 3.16Å
318M54.9Low57.1Low155 Ų15586.8 Ų86.876%0.76445%0.447SS*.Hα-helixtrans-64.6-31.3-179.9-70.3-178.367.100113.5E314 L315E314-M318 WeakPolarHBondContact O-CG 3.23Å; E314-M318 PolarHBondContact O-N 3.48Å; L315-M318 PolarHBondContact O-N 3.36Å
319I56.6Low55.5Low131 Ų13192.8 Ų92.867%0.67247%0.472SS*.Hα-helixtrans-91.3-40.9-175.6-63166.3000112L315 E317L315-I319 HydrophobicContact CB-CD1 4.26Å; L315-I319 HydrophobicContact CD2-CD1 4.41Å; L315-I319 WeakPolarHBondContact O-CB 3.14Å; L315-I319 WeakPolarHBondContact O-CD1 3.37Å; L315-I319 WeakPolarHBondContact O-CG1 3.32Å; L315-I319 PolarHBondContact O-N 2.94Å; E317-I319 VanDerWaalsContact C-N 3.3Å; E317-I319 PolarHBondContact O-N 3.49Å
320L51.3Low54Low122 Ų122101.4 Ų101.464%0.63951%0.509SS*.Hα-helixtrans-86-29.3-175.1-73.4153.2000113.3E316E316-L320 HydrophobicContact CB-CD1 4.11Å; E316-L320 HydrophobicContact CG-CD1 4.32Å; E316-L320 WeakPolarHBondContact O-CB 3.41Å; E316-L320 PolarHBondContact O-N 2.86Å
321E50.3Low52.9Low58 Ų58107.2 Ų107.227%0.27153%0.525SS..  trans-105.583.2-174.5-68.7-176.4-156.500111.7K36 E317 K323K36-E321 IonicContact NZ-OE1 3.58Å; K36-E321 PolarHBondContact NZ-OE1 2.71Å; E317-E321 PolarHBondContact O-N 2.88Å; E317-E321 VanDerWaalsContact O-N 3.16Å; E321-K323 PolarHBondContact O-N 3.35Å
322S40.5Very low52Low120 Ų120106.1 Ų106.184%0.83952%0.515SS*.SBendtrans-57.3-9176.152.90000115.3
323K46.3Very low51Low147 Ų147106.5 Ų106.564%0.63953%0.525SS*.SBendtrans-148.1124.7170.1-64.5-177.2-178.5169.30110.3E321E321-K323 PolarHBondContact O-N 3.35Å
324P45.7Very low49.9Very low96 Ų96112.5 Ų112.562%0.62355%0.546SS*.  trans-60.5149.4179.618.7-26.7000112.2H326P324-H326 PolarHBondContact O-N 3.11Å
325L51.7Low49Very low59 Ų59116.4 Ų116.431%0.30956%0.562SS.*G310 helixtrans-41.9-23.8-170.8-83.4102.5000117K327 K328L325-K327 PolarHBondContact O-N 3.37Å; L325-K328 PolarHBondContact O-N 3.03Å
326H48.7Very low48.5Very low142 Ų142116.9 Ų116.966%0.65757%0.57SS**G310 helixtrans-53.4-10.4-178.4-91.275.3000116.4P324P324-H326 PolarHBondContact O-N 3.11Å
327K43.9Very low47.8Very low152 Ų152125 Ų12566%0.66160%0.598SS**G310 helixtrans-114.83.7-174.8-69.9-176.9180175.80116L325L325-K327 PolarHBondContact O-N 3.37Å
328K49.7Very low47.1Very low107 Ų107129.8 Ų129.847%0.46562%0.62SS.*SBendtrans-68.6-37.8177.5-104.4-171.4172.5-166.20113.2E94 L325 K330 R331 L332E94-K328 IonicContact OE2-NZ 2.68Å; E94-K328 PolarHBondContact OE2-NZ 3.26Å; L325-K328 PolarHBondContact O-N 3.03Å; K328-K330 PolarHBondContact O-N 3.39Å; K328-R331 PolarHBondContact O-N 2.94Å; K328-L332 PolarHBondContact O-N 3.06Å
329K45.8Very low46.4Very low138 Ų138129.8 Ų129.860%0.662%0.618SS**Hα-helixtrans-51.6-33.3-178.1-98.6-171.9167.1-1690115.4D21D21-K329 WeakPolarHBondContact OD1-CE 3.4Å; D21-K329 IonicContact OD1-NZ 3.55Å; D21-K329 PolarHBondContact OD1-NZ 3.09Å; D21-K329 IonicContact OD2-NZ 2.65Å; D21-K329 PolarHBondContact OD2-NZ 3.01Å
330K42.9Very low45.7Very low195 Ų195126.8 Ų126.885%0.84862%0.62SS**Hα-helixtrans-87-11.6-178-110.7-178.8178.6179.60114.7K328K328-K330 PolarHBondContact O-N 3.39Å
331R46.6Very low45.7Very low190 Ų190126.8 Ų126.872%0.71763%0.63SS**Hα-helixtrans-96.1-33.4-178.8-93.4171.859.4-161.8-1.8113.3K328 R334 K335K328-R331 PolarHBondContact O-N 2.94Å; R331-R334 PolarHBondContact O-N 3.07Å; R331-K335 PolarHBondContact O-N 3.49Å
332L46.5Very low45.3Very low51 Ų51131 Ų13127%0.26765%0.654SS.*Hα-helixtrans-70.8-41.7-177.4-85.9140.7000112.8E94 K328 R334 K335 T336E94-L332 WeakPolarHBondContact OE1-CD1 3.35Å; E94-L332 WeakPolarHBondContact OE1-CD2 3.41Å; K328-L332 PolarHBondContact O-N 3.06Å; L332-R334 PolarHBondContact O-N 3.35Å; L332-K335 PolarHBondContact O-N 2.68Å; L332-T336 PolarHBondContact O-N 3.25Å; L332-T336 VanDerWaalsContact O-N 3.09Å; L332-T336 PolarHBondContact O-OG1 2.97Å
333A45.8Very low45.8Very low76 Ų76129.1 Ų129.163%0.62865%0.654SS**Hα-helixtrans-57.5-20.2173.100000114
334R44.3Very low46.4Very low180 Ų180124.3 Ų124.368%0.67964%0.639SS**Hα-helixtrans-88.8-30.1174.3-154.1178.681.2175.36112.9R331 L332R331-R334 PolarHBondContact O-N 3.07Å; L332-R334 PolarHBondContact O-N 3.35Å
335K42.6Very low47.2Very low128 Ų128125 Ų12556%0.55764%0.643SS**Hα-helixtrans-82.1-36.3-177.6-106.8-170.7172.5-162.90113.3R331 L332 R337 E338 Q339R331-K335 PolarHBondContact O-N 3.49Å; L332-K335 PolarHBondContact O-N 2.68Å; K335-R337 PolarHBondContact O-N 3.16Å; K335-E338 PolarHBondContact O-N 3.08Å; K335-E338 VanDerWaalsContact O-N 3.08Å; K335-Q339 PolarHBondContact O-N 2.64Å
336T46.8Very low47.7Very low107 Ų107129.6 Ų129.666%0.65666%0.663SS**THydrogen-bonded Turntrans-66.1-18.4178.3-34.70000112.7L332L332-T336 PolarHBondContact O-N 3.25Å; L332-T336 VanDerWaalsContact O-N 3.09Å; L332-T336 PolarHBondContact O-OG1 2.97Å
337R46.6Very low48.8Very low234 Ų234127 Ų12788%0.88365%0.654SS**THydrogen-bonded Turntrans-88.4-16.9173.5-97.4-178.3169.1-178.6-2.9114.6K335K335-R337 PolarHBondContact O-N 3.16Å
338E41.4Very low50.5Low137 Ų137121.9 Ų121.964%0.6465%0.645SS**THydrogen-bonded Turntrans-106.6-17-170.4-76.4179.6172.600114.2K335K335-E338 PolarHBondContact O-N 3.08Å; K335-E338 VanDerWaalsContact O-N 3.08Å
339Q41.4Very low52.1Low155 Ų155123.1 Ų123.172%0.72465%0.652SS**  trans-105.789.4175.2-72.8-173.7-20.700110.5K335K335-Q339 PolarHBondContact O-N 2.64Å
340G41.6Very low53.9Low69 Ų69119 Ų11971%0.71164%0.636SS**  trans-57.2152.1164.800000111.6D342G340-D342 PolarHBondContact O-N 3.1Å
341S49.7Very low56Low122 Ų122114.5 Ų114.585%0.85362%0.618SS**  trans-44.9111.8-178.458.80000113.8
342D42Very low58Low146 Ų146111.3 Ų111.378%0.78161%0.612SS**  trans-95.196.8161.9-128.9-7.3000107.9G340 S344 N347G340-D342 PolarHBondContact O-N 3.1Å; D342-S344 PolarHBondContact O-N 3.23Å; D342-N347 PolarHBondContact O-ND2 3.39Å
343G51.2Low60Low80 Ų80113.8 Ų113.883%0.82562%0.617SS**  trans-77.772.6-168.800000113.6
344S59.4Low62.1Low47 Ų47111.8 Ų111.833%0.32960%0.596SS.*  trans-92.8143164.280.90000110.7D342 Q346 N347 G348D342-S344 PolarHBondContact O-N 3.23Å; S344-Q346 PolarHBondContact O-N 3.19Å; S344-N347 PolarHBondContact O-N 3.22Å; S344-N347 VanDerWaalsContact O-N 3.12Å; S344-N347 WeakPolarHBondContact OG-CB 3.34Å; S344-N347 PolarHBondContact OG-N 2.79Å; S344-N347 PolarHBondContact OG-ND2 3.33Å; S344-G348 PolarHBondContact O-N 3.41Å
345P62.2Low64.2Low111 Ų111106.8 Ų106.872%0.72158%0.583SS**Hα-helixtrans-58.7-31178-22.831.4000113.3G348 Q349P345-G348 PolarHBondContact O-N 3.46Å; P345-Q349 PolarHBondContact O-N 3.06Å
346Q63.8Low66.5Low155 Ų155103.2 Ų103.272%0.72457%0.569SS**Hα-helixtrans-69-38.3177.5-70.5179.7-2.400112S344 G348 Q349 L350S344-Q346 PolarHBondContact O-N 3.19Å; Q346-G348 VanDerWaalsContact C-N 3.32Å; Q346-G348 PolarHBondContact O-N 3.47Å; Q346-Q349 PolarHBondContact O-N 2.7Å; Q346-L350 WeakPolarHBondContact O-CB 3.43Å; Q346-L350 PolarHBondContact O-N 3.4Å
347N71.4Confident68.5Low87 Ų8798.3 Ų98.347%0.46554%0.539SS..Hα-helixtrans-64.8-37.2174-75.8-9.5000111.6D342 S344 L350 Q351D342-N347 PolarHBondContact O-ND2 3.39Å; S344-N347 PolarHBondContact O-N 3.22Å; S344-N347 VanDerWaalsContact O-N 3.12Å; S344-N347 WeakPolarHBondContact OG-CB 3.34Å; S344-N347 PolarHBondContact OG-N 2.79Å; S344-N347 PolarHBondContact OG-ND2 3.33Å; N347-L350 PolarHBondContact O-N 3.29Å; N347-Q351 WeakPolarHBondContact O-CB 3.18Å; N347-Q351 PolarHBondContact O-N 3.11Å
348G78.2Confident70.6Confident45 Ų4591.8 Ų91.846%0.46452%0.519SS..Hα-helixtrans-63.7-44.8176.200000113.3S344 P345 Q346 Q351 Q352S344-G348 PolarHBondContact O-N 3.41Å; P345-G348 PolarHBondContact O-N 3.46Å; Q346-G348 VanDerWaalsContact C-N 3.32Å; Q346-G348 PolarHBondContact O-N 3.47Å; G348-Q351 PolarHBondContact O-N 3.22Å; G348-Q352 WeakPolarHBondContact O-CB 3.27Å; G348-Q352 PolarHBondContact O-N 3.49Å
349Q83.2Confident72.9Confident132 Ų13293.2 Ų93.262%0.61752%0.518SS*.Hα-helixtrans-65.7-39.8176.5-70.9-178.81.500112.4P345 Q346 Q352 R353P345-Q349 PolarHBondContact O-N 3.06Å; Q346-Q349 PolarHBondContact O-N 2.7Å; Q349-Q352 PolarHBondContact O-N 2.88Å; Q349-R353 WeakPolarHBondContact O-CG 3.46Å; Q349-R353 PolarHBondContact O-N 3.3Å; Q349-R353 VanDerWaalsContact O-N 3.09Å
350L85.1Confident75.2Confident51 Ų5190.1 Ų90.127%0.26751%0.507SS..Hα-helixtrans-64.7-45.7177.6-177.563.6000111.4L57 V60 Q346 N347 Q352 R353 L354L57-L350 HydrophobicContact CD1-CD1 3.81Å; L57-L350 HydrophobicContact CD1-CD2 3.72Å; L57-L350 HydrophobicContact CD1-CG 4.14Å; V60-L350 HydrophobicContact CG1-CD1 3.75Å; Q346-L350 WeakPolarHBondContact O-CB 3.43Å; Q346-L350 PolarHBondContact O-N 3.4Å; N347-L350 PolarHBondContact O-N 3.29Å; L350-Q352 VanDerWaalsContact C-N 3.35Å; L350-Q352 PolarHBondContact O-N 3.03Å; L350-R353 PolarHBondContact O-N 3.2Å; L350-L354 HydrophobicContact CG-CD1 4.48Å; L350-L354 PolarHBondContact O-N 3.09Å
351Q85.4Confident77.6Confident102 Ų10287.5 Ų87.548%0.47748%0.476SS..Hα-helixtrans-60.9-44.6177-171.660.145.700111.2N347 G348 R353 L354 D355N347-Q351 WeakPolarHBondContact O-CB 3.18Å; N347-Q351 PolarHBondContact O-N 3.11Å; G348-Q351 PolarHBondContact O-N 3.22Å; Q351-R353 VanDerWaalsContact C-N 3.28Å; Q351-R353 PolarHBondContact O-N 2.59Å; Q351-L354 WeakPolarHBondContact O-CB 3.4Å; Q351-L354 PolarHBondContact O-N 3.2Å; Q351-L354 VanDerWaalsContact O-N 3.09Å; Q351-D355 PolarHBondContact NE2-OD1 3.16Å; Q351-D355 PolarHBondContact O-N 3.3Å
352Q89.1Confident79.4Confident123 Ų12384.8 Ų84.858%0.57545%0.451SS*.Hα-helixtrans-59.3-38.5176.2-170.6-177.914.900112.4G348 Q349 L350 D355 N356G348-Q352 WeakPolarHBondContact O-CB 3.27Å; G348-Q352 PolarHBondContact O-N 3.49Å; Q349-Q352 PolarHBondContact O-N 2.88Å; L350-Q352 VanDerWaalsContact C-N 3.35Å; L350-Q352 PolarHBondContact O-N 3.03Å; Q352-D355 PolarHBondContact O-N 3.41Å; Q352-N356 PolarHBondContact O-N 2.73Å; Q352-N356 PolarHBondContact O-ND2 3.44Å; Q352-N356 PolarHBondContact O-OD1 2.97Å
353R89.3Confident81.9Confident102 Ų10281.1 Ų81.139%0.38543%0.434SS..Hα-helixtrans-67-39.9175.5-70.9178.178.7-161.1-1.9111.7V60 N63 Q349 L350 Q351 N356 V357V60-R353 HydrophobicContact CG1-CB 3.69Å; V60-R353 HydrophobicContact CG1-CG 4.44Å; V60-R353 HydrophobicContact CG2-CB 4.46Å; V60-R353 PolarHBondContact O-NH1 3.17Å; V60-R353 PolarHBondContact O-NH2 2.86Å; N63-R353 PolarHBondContact OD1-NH2 2.96Å; Q349-R353 WeakPolarHBondContact O-CG 3.46Å; Q349-R353 PolarHBondContact O-N 3.3Å; Q349-R353 VanDerWaalsContact O-N 3.09Å; L350-R353 PolarHBondContact O-N 3.2Å; Q351-R353 VanDerWaalsContact C-N 3.28Å; Q351-R353 PolarHBondContact O-N 2.59Å; R353-N356 PolarHBondContact O-N 3.14Å; R353-V357 VanDerWaalsContact O-CG2 3.3Å; R353-V357 WeakPolarHBondContact O-CG2 2.89Å; R353-V357 PolarHBondContact O-N 2.98Å
354L88.9Confident84Confident34 Ų3478.4 Ų78.418%0.17840%0.4CS..Hα-helixtrans-64.5-41174.6-70.8169.5000111.9K56 V60 L350 Q351 N356 V357 Q358K56-L354 HydrophobicContact CB-CD2 3.74Å; V60-L354 HydrophobicContact CG2-CD2 4Å; L350-L354 HydrophobicContact CG-CD1 4.48Å; L350-L354 PolarHBondContact O-N 3.09Å; Q351-L354 WeakPolarHBondContact O-CB 3.4Å; Q351-L354 PolarHBondContact O-N 3.2Å; Q351-L354 VanDerWaalsContact O-N 3.09Å; L354-N356 VanDerWaalsContact C-N 3.3Å; L354-N356 PolarHBondContact O-N 2.77Å; L354-V357 WeakPolarHBondContact O-CB 3.32Å; L354-V357 PolarHBondContact O-N 2.5Å; L354-V357 VanDerWaalsContact O-N 3.12Å; L354-Q358 PolarHBondContact O-N 2.72Å
355D89.1Confident85.7Confident76 Ų7677.1 Ų77.141%0.40639%0.389SS..Hα-helixtrans-64.6-36.5175.9-62.2-17.3000111.4Q351 Q352 Q358 R359Q351-D355 PolarHBondContact NE2-OD1 3.16Å; Q351-D355 PolarHBondContact O-N 3.3Å; Q352-D355 PolarHBondContact O-N 3.41Å; D355-Q358 WeakPolarHBondContact O-CB 3.46Å; D355-Q358 PolarHBondContact O-N 2.9Å; D355-R359 PolarHBondContact O-N 3.48Å
356N90.3Very high87.2Confident52 Ų5272.3 Ų72.328%0.27836%0.357SS..Hα-helixtrans-65.2-39.9172-68.1-18.6000111.6Q352 R353 L354 Q358 R359 D360Q352-N356 PolarHBondContact O-N 2.73Å; Q352-N356 PolarHBondContact O-ND2 3.44Å; Q352-N356 PolarHBondContact O-OD1 2.97Å; R353-N356 PolarHBondContact O-N 3.14Å; L354-N356 VanDerWaalsContact C-N 3.3Å; L354-N356 PolarHBondContact O-N 2.77Å; N356-Q358 VanDerWaalsContact C-N 3.3Å; N356-Q358 PolarHBondContact O-N 3.47Å; N356-R359 PolarHBondContact O-N 2.82Å; N356-R359 PolarHBondContact OD1-NH1 3.15Å; N356-D360 VanDerWaalsContact O-CB 3.3Å; N356-D360 WeakPolarHBondContact O-CB 3.06Å; N356-D360 PolarHBondContact O-N 3.13Å
357V90.1Very high88.5Confident4 Ų467.6 Ų67.62%0.02433%0.334CS..Hα-helixtrans-57.6-47171.9-176.30000110.1K56 V60 V65 M96 R353 L354 R359 D360 F361K56-V357 HydrophobicContact CD-CG1 4.4Å; K56-V357 HydrophobicContact CG-CG1 4.31Å; V60-V357 HydrophobicContact CG2-CG2 3.8Å; V65-V357 HydrophobicContact CB-CG2 4.45Å; V65-V357 HydrophobicContact CG1-CG1 4.39Å; V65-V357 HydrophobicContact CG1-CG2 3.77Å; V65-V357 HydrophobicContact CG2-CG2 3.79Å; M96-V357 HydrophobicContact CE-CG1 4.47Å; M96-V357 HydrophobicContact CG-CG1 4.31Å; M96-V357 HydrophobicContact SD-CG1 3.57Å; M96-V357 VanDerWaalsContact SD-CG1 3.57Å; R353-V357 VanDerWaalsContact O-CG2 3.3Å; R353-V357 WeakPolarHBondContact O-CG2 2.89Å; R353-V357 PolarHBondContact O-N 2.98Å; L354-V357 WeakPolarHBondContact O-CB 3.32Å; L354-V357 PolarHBondContact O-N 2.5Å; L354-V357 VanDerWaalsContact O-N 3.12Å; V357-R359 VanDerWaalsContact C-N 3.29Å; V357-R359 PolarHBondContact O-N 3.14Å; V357-D360 PolarHBondContact O-N 3.32Å; V357-F361 VanDerWaalsContact O-CB 3.28Å; V357-F361 WeakPolarHBondContact O-CB 3.28Å; V357-F361 PolarHBondContact O-N 3.42Å; V357-F361 VanDerWaalsContact O-N 3.08Å
358Q89.3Confident89.3Confident97 Ų9767.3 Ų67.345%0.45333%0.329SS..Hα-helixtrans-58.5-42.8179.4-174.966.223.300112Q91 L354 D355 N356Q91-Q358 PolarHBondContact NE2-O 3.09Å; Q91-Q358 VanDerWaalsContact OE1-OE1 3.11Å; L354-Q358 PolarHBondContact O-N 2.72Å; D355-Q358 WeakPolarHBondContact O-CB 3.46Å; D355-Q358 PolarHBondContact O-N 2.9Å; N356-Q358 VanDerWaalsContact C-N 3.3Å; N356-Q358 PolarHBondContact O-N 3.47Å
359R89.8Confident89.5Confident167 Ų16767.8 Ų67.863%0.6333%0.325SS*.Hα-helixtrans-72.1-42.4-178.4-167.5-170.4-55.11207.5113.2D355 N356 V357D355-R359 PolarHBondContact O-N 3.48Å; N356-R359 PolarHBondContact O-N 2.82Å; N356-R359 PolarHBondContact OD1-NH1 3.15Å; V357-R359 VanDerWaalsContact C-N 3.29Å; V357-R359 PolarHBondContact O-N 3.14Å
360D91Very high89.5Confident91 Ų9166.7 Ų66.749%0.48732%0.315SS..Hα-helixtrans-89-9.7-169.6-60.2-14.2000112.7L69 N356 V357L69-D360 HydrophobicContact CD1-CB 4.18Å; N356-D360 VanDerWaalsContact O-CB 3.3Å; N356-D360 WeakPolarHBondContact O-CB 3.06Å; N356-D360 PolarHBondContact O-N 3.13Å; V357-D360 PolarHBondContact O-N 3.32Å
361F91.9Very high89.1Confident14 Ų1471.1 Ų71.16%0.06133%0.333CS..  trans-68.3132.1179.3-170-91.3000111.9L69 L72 F90 Q91 M96 V357 V363L69-F361 HydrophobicContact CD2-CD2 4.09Å; L72-F361 HydrophobicContact CD1-CD2 4.11Å; L72-F361 HydrophobicContact CD1-CE2 3.49Å; L72-F361 VanDerWaalsContact CD1-CE2 3.49Å; L72-F361 HydrophobicContact CD1-CZ 3.9Å; F90-F361 VanDerWaalsContact C-CE1 3.45Å; F90-F361 WeakPolarHBondContact O-CE1 3.18Å; F90-F361 VanDerWaalsContact O-CZ 3.32Å; F90-F361 WeakPolarHBondContact O-CZ 3.21Å; Q91-F361 HydrophobicContact CB-CD1 4.12Å; Q91-F361 HydrophobicContact CB-CE1 4.15Å; Q91-F361 HydrophobicContact CB-CG 4.34Å; Q91-F361 HydrophobicContact CB-CZ 4.4Å; Q91-F361 VanDerWaalsContact CD-CB 3.5Å; Q91-F361 HydrophobicContact CG-CB 4.49Å; Q91-F361 HydrophobicContact CG-CD1 3.85Å; Q91-F361 HydrophobicContact CG-CE1 4.3Å; Q91-F361 HydrophobicContact CG-CG 4.16Å; Q91-F361 VanDerWaalsContact NE2-CB 3.27Å; M96-F361 HydrophobicContact CB-CD2 4.33Å; M96-F361 HydrophobicContact CB-CE2 3.62Å; M96-F361 HydrophobicContact CB-CZ 4.24Å; M96-F361 HydrophobicContact CG-CD2 3.73Å; M96-F361 HydrophobicContact CG-CE2 3.54Å; M96-F361 HydrophobicContact CG-CZ 4.45Å; M96-F361 HydrophobicContact SD-CD2 3.67Å; M96-F361 HydrophobicContact SD-CE2 3.77Å; V357-F361 VanDerWaalsContact O-CB 3.28Å; V357-F361 WeakPolarHBondContact O-CB 3.28Å; V357-F361 PolarHBondContact O-N 3.42Å; V357-F361 VanDerWaalsContact O-N 3.08Å; F361-V363 HydrophobicContact CD1-CG2 4.44Å
362I87.4Confident88.6Confident65 Ų6570.9 Ų70.933%0.33334%0.338SS..  trans-92.9110.7-179.1-56.1171.4000108.6S89S89-I362 PolarHBondContact OG-O 3.32Å
363V93.8Very high87.7Confident69 Ų6969.5 Ų69.542%0.41834%0.337SS..  trans-72.8127.5167.5177.90000108.3S89 F361S89-V363 WeakPolarHBondContact O-CA 3.41Å; S89-V363 WeakPolarHBondContact O-CG1 3.46Å; F361-V363 HydrophobicContact CD1-CG2 4.44Å
364F95.1Very high86.7Confident23 Ų2367.9 Ų67.910%0.10134%0.339CS..EExtended strand (participates in β ladder)trans-129.5142.4-178.6178.7-102.9000110.4Q76 F86 Y88 S89 R366Q76-F364 HydrophobicContact CB-CD1 4.49Å; Q76-F364 HydrophobicContact CB-CD2 3.77Å; Q76-F364 HydrophobicContact CB-CE1 4.43Å; Q76-F364 HydrophobicContact CB-CE2 3.75Å; Q76-F364 HydrophobicContact CB-CG 4.15Å; Q76-F364 HydrophobicContact CB-CZ 4.08Å; F86-F364 AromaticContact CD1-CD1 3.47Å; F86-F364 HydrophobicContact CD1-CD1 3.47Å; F86-F364 VanDerWaalsContact CD1-CD1 3.47Å; F86-F364 AromaticContact CD1-CE1 3.64Å; F86-F364 HydrophobicContact CD1-CE1 3.64Å; F86-F364 HydrophobicContact CD1-CG 4.31Å; F86-F364 HydrophobicContact CE1-CB 3.82Å; F86-F364 AromaticContact CE1-CD1 3.16Å; F86-F364 HydrophobicContact CE1-CD1 3.16Å; F86-F364 AromaticContact CE1-CE1 3.85Å; F86-F364 HydrophobicContact CE1-CE1 3.85Å; F86-F364 AromaticContact CE1-CG 3.68Å; F86-F364 HydrophobicContact CE1-CG 3.68Å; F86-F364 HydrophobicContact CZ-CB 4.29Å; F86-F364 HydrophobicContact CZ-CD1 4.04Å; Y88-F364 CarbonylContact C-O 3.58Å; Y88-F364 VanDerWaalsContact CA-O 3.24Å; Y88-F364 WeakPolarHBondContact CA-O 3.16Å; S89-F364 PolarHBondContact N-O 3.43Å; S89-F364 PolarHBondContact O-N 3.12Å; S89-F364 VanDerWaalsContact OG-CB 3.23Å; S89-F364 WeakPolarHBondContact OG-CB 3.47Å; S89-F364 PolarHBondContact OG-N 2.88Å; F364-R366 HydrophobicContact CE1-CB 3.78Å; F364-R366 HydrophobicContact CZ-CB 4Å
365N95.1Very high85.6Confident19 Ų1970.5 Ų70.510%0.10235%0.353CS..EExtended strand (participates in β ladder)trans-145.2104.5174.2-179.4-19.7000109.8V18 Y88 E367 K368 S369V18-N365 VanDerWaalsContact CG2-ND2 3.33Å; V18-N365 WeakPolarHBondContact CG2-ND2 3.32Å; Y88-N365 HydrophobicContact CD1-CB 4.25Å; Y88-N365 WeakPolarHBondContact CE1-OD1 3.28Å; N365-E367 VanDerWaalsContact C-N 3.27Å; N365-E367 PolarHBondContact O-N 3.22Å; N365-E367 WeakPolarHBondContact OD1-CB 3.43Å; N365-E367 PolarHBondContact OD1-N 3.45Å; N365-K368 HydrophobicContact CB-CB 4.22Å; N365-K368 HydrophobicContact CB-CD 4.28Å; N365-K368 HydrophobicContact CB-CG 4.25Å; N365-K368 PolarHBondContact O-N 3.44Å; N365-K368 PolarHBondContact OD1-N 3.17Å; N365-S369 PolarHBondContact O-N 3.09Å; N365-S369 VanDerWaalsContact O-N 3.11Å; N365-S369 PolarHBondContact O-OG 3.48Å
366R94.2Very high84.1Confident11 Ų1169.9 Ų69.94%0.04236%0.355CS..Hα-helixtrans-61.6-33.3-179.6-170.9173.6-62.3-90.3-2.2113L78 E79 F86 W87 F364 K368 S369 R370L78-R366 PolarHBondContact O-NH1 3.22Å; L78-R366 PolarHBondContact O-NH2 3.14Å; E79-R366 IonicContact OE2-CZ 3.05Å; E79-R366 IonicContact OE2-NH1 3.11Å; E79-R366 PolarHBondContact OE2-NH1 2.93Å; F86-R366 PolarHBondContact O-NE 3.19Å; F86-R366 PolarHBondContact O-NH2 3.2Å; W87-R366 HydrophobicContact CE3-CB 4.16Å; W87-R366 PolarHBondContact O-N 2.9Å; F364-R366 HydrophobicContact CE1-CB 3.78Å; F364-R366 HydrophobicContact CZ-CB 4Å; R366-K368 VanDerWaalsContact C-N 3.33Å; R366-K368 PolarHBondContact O-N 3.48Å; R366-S369 PolarHBondContact O-N 2.83Å; R366-R370 HydrophobicContact CG-CG 4.5Å; R366-R370 WeakPolarHBondContact O-CG 3.36Å; R366-R370 PolarHBondContact O-N 3.46Å
367E90.8Very high82.6Confident55 Ų5570 Ų7026%0.25736%0.36SS..Hα-helixtrans-64.5-41.1178.6-61.9179.7141.400111K42 W87 Y88 N365 R370 K371K42-E367 IonicContact NZ-OE2 2.68Å; K42-E367 PolarHBondContact NZ-OE2 2.77Å; W87-E367 HydrophobicContact CE3-CG 4.39Å; W87-E367 HydrophobicContact CZ3-CG 4.35Å; Y88-E367 HydrophobicContact CE1-CG 4.18Å; Y88-E367 PolarHBondContact OH-OE1 3Å; Y88-E367 PolarHBondContact OH-OE2 2.88Å; N365-E367 VanDerWaalsContact C-N 3.27Å; N365-E367 PolarHBondContact O-N 3.22Å; N365-E367 WeakPolarHBondContact OD1-CB 3.43Å; N365-E367 PolarHBondContact OD1-N 3.45Å; E367-R370 PolarHBondContact O-N 3.22Å; E367-K371 PolarHBondContact O-N 3.17Å; E367-K371 VanDerWaalsContact O-N 3.14Å
368K87.6Confident81.2Confident82 Ų8275.7 Ų75.736%0.35739%0.386SS..Hα-helixtrans-64.4-46.8173.5-75-173.7179.3-1730111.2D16 N365 R366 R370 K371 V372D16-K368 VanDerWaalsContact C-NZ 3.28Å; D16-K368 WeakPolarHBondContact O-CE 3.46Å; D16-K368 PolarHBondContact O-NZ 3.27Å; N365-K368 HydrophobicContact CB-CB 4.22Å; N365-K368 HydrophobicContact CB-CD 4.28Å; N365-K368 HydrophobicContact CB-CG 4.25Å; N365-K368 PolarHBondContact O-N 3.44Å; N365-K368 PolarHBondContact OD1-N 3.17Å; R366-K368 VanDerWaalsContact C-N 3.33Å; R366-K368 PolarHBondContact O-N 3.48Å; K368-R370 VanDerWaalsContact C-N 3.26Å; K368-R370 PolarHBondContact O-N 3.24Å; K368-K371 PolarHBondContact O-N 3.03Å; K368-K371 VanDerWaalsContact O-N 3.15Å; K368-V372 WeakPolarHBondContact O-CG2 3.07Å; K368-V372 PolarHBondContact O-N 2.86Å; K368-V372 VanDerWaalsContact O-N 3.07Å
369S82.4Confident79.6Confident54 Ų5475.9 Ų75.938%0.37839%0.389SS..Hα-helixtrans-57.6-39.5178.2-56.80000112.3N365 R366 V373N365-S369 PolarHBondContact O-N 3.09Å; N365-S369 VanDerWaalsContact O-N 3.11Å; N365-S369 PolarHBondContact O-OG 3.48Å; R366-S369 PolarHBondContact O-N 2.83Å; S369-V373 WeakPolarHBondContact O-CG2 3.45Å; S369-V373 PolarHBondContact O-N 3.31Å
370R84.1Confident77.9Confident109 Ų10970.4 Ų70.441%0.41138%0.377SS..Hα-helixtrans-66.2-42.9175.7-74.9-179177.3-176.60.3112.8E79 R366 E367 K368 V372 V373 V374E79-R370 IonicContact OE1-CZ 3.06Å; E79-R370 IonicContact OE1-NE 3.25Å; E79-R370 IonicContact OE1-NH2 2.56Å; E79-R370 PolarHBondContact OE1-NH2 3.11Å; R366-R370 HydrophobicContact CG-CG 4.5Å; R366-R370 WeakPolarHBondContact O-CG 3.36Å; R366-R370 PolarHBondContact O-N 3.46Å; E367-R370 PolarHBondContact O-N 3.22Å; K368-R370 VanDerWaalsContact C-N 3.26Å; K368-R370 PolarHBondContact O-N 3.24Å; R370-V372 PolarHBondContact O-N 3.36Å; R370-V373 PolarHBondContact O-N 3.42Å; R370-V374 WeakPolarHBondContact O-CG2 3.3Å; R370-V374 PolarHBondContact O-N 3.46Å
371K76.6Confident76.1Confident145 Ų14569.7 Ų69.763%0.6338%0.376SS*.Hα-helixtrans-60-44.6177-73.2-177.7179.5-174.40111.9E367 K368 V373 V374 D375E367-K371 PolarHBondContact O-N 3.17Å; E367-K371 VanDerWaalsContact O-N 3.14Å; K368-K371 PolarHBondContact O-N 3.03Å; K368-K371 VanDerWaalsContact O-N 3.15Å; K371-V373 VanDerWaalsContact C-N 3.29Å; K371-V373 PolarHBondContact O-N 3.22Å; K371-V374 PolarHBondContact O-N 3.2Å; K371-V374 VanDerWaalsContact O-N 3.14Å; K371-D375 WeakPolarHBondContact O-CB 3.36Å; K371-D375 VanDerWaalsContact O-CG 3.27Å; K371-D375 PolarHBondContact O-N 2.6Å
372V74Confident74.2Confident97 Ų9771.5 Ų71.559%0.58839%0.39SS*.Hα-helixtrans-60.9-38.4177.61760000111.9K368 R370 S376K368-V372 WeakPolarHBondContact O-CG2 3.07Å; K368-V372 PolarHBondContact O-N 2.86Å; K368-V372 VanDerWaalsContact O-N 3.07Å; R370-V372 PolarHBondContact O-N 3.36Å; V372-S376 VanDerWaalsContact O-CB 3.29Å; V372-S376 WeakPolarHBondContact O-CB 3.43Å; V372-S376 PolarHBondContact O-N 3.17Å; V372-S376 PolarHBondContact O-OG 3.24Å
373V70.7Confident72.6Confident93 Ų9374.3 Ų74.356%0.56440%0.402SS*.Hα-helixtrans-67.6-42.1175.6174.30000111.3S369 R370 K371 S376 S377S369-V373 WeakPolarHBondContact O-CG2 3.45Å; S369-V373 PolarHBondContact O-N 3.31Å; R370-V373 PolarHBondContact O-N 3.42Å; K371-V373 VanDerWaalsContact C-N 3.29Å; K371-V373 PolarHBondContact O-N 3.22Å; V373-S376 WeakPolarHBondContact CA-OG 3.42Å; V373-S376 PolarHBondContact O-OG 3.35Å; V373-S377 WeakPolarHBondContact O-CB 3.37Å; V373-S377 PolarHBondContact O-N 2.79Å; V373-S377 PolarHBondContact O-OG 3.23Å
374V68.9Low70.5Confident69 Ų6978 Ų7842%0.41841%0.413SS..Hα-helixtrans-64.3-50.7176.6175.80000110.5R370 K371 S376 S377 E378R370-V374 WeakPolarHBondContact O-CG2 3.3Å; R370-V374 PolarHBondContact O-N 3.46Å; K371-V374 PolarHBondContact O-N 3.2Å; K371-V374 VanDerWaalsContact O-N 3.14Å; V374-S376 VanDerWaalsContact C-N 3.35Å; V374-S376 PolarHBondContact O-N 3.06Å; V374-S377 PolarHBondContact O-N 3.12Å; V374-S377 VanDerWaalsContact O-N 3.11Å; V374-S377 PolarHBondContact O-OG 3.33Å; V374-E378 HydrophobicContact CG1-CG 4.4Å; V374-E378 WeakPolarHBondContact O-CG 3.29Å; V374-E378 PolarHBondContact O-N 3.25Å
375D64.7Low68.3Low88 Ų8881.5 Ų81.547%0.47143%0.432SS..Hα-helixtrans-59.5-44.1179.7-66.3-18.2000111.3K371 S377 E378 L379K371-D375 WeakPolarHBondContact O-CB 3.36Å; K371-D375 VanDerWaalsContact O-CG 3.27Å; K371-D375 PolarHBondContact O-N 2.6Å; D375-S377 PolarHBondContact O-N 2.79Å; D375-E378 PolarHBondContact O-N 2.99Å; D375-L379 WeakPolarHBondContact O-CB 3.47Å; D375-L379 VanDerWaalsContact O-CD1 3.32Å; D375-L379 WeakPolarHBondContact O-CD1 3.34Å; D375-L379 PolarHBondContact O-N 2.88Å
376S58.5Low66.2Low64 Ų6487.1 Ų87.145%0.44846%0.456SS..Hα-helixtrans-65.7-37176.455.50000113.1V372 V373 V374 S380V372-S376 VanDerWaalsContact O-CB 3.29Å; V372-S376 WeakPolarHBondContact O-CB 3.43Å; V372-S376 PolarHBondContact O-N 3.17Å; V372-S376 PolarHBondContact O-OG 3.24Å; V373-S376 WeakPolarHBondContact CA-OG 3.42Å; V373-S376 PolarHBondContact O-OG 3.35Å; V374-S376 VanDerWaalsContact C-N 3.35Å; V374-S376 PolarHBondContact O-N 3.06Å; S376-S380 WeakPolarHBondContact O-CB 3.38Å; S376-S380 PolarHBondContact O-N 3.47Å
377S57.9Low64Low54 Ų5490 Ų9038%0.37848%0.482SS..Hα-helixtrans-66.3-41.7173.873.10000111.9V373 V374 D375 S380 T381V373-S377 WeakPolarHBondContact O-CB 3.37Å; V373-S377 PolarHBondContact O-N 2.79Å; V373-S377 PolarHBondContact O-OG 3.23Å; V374-S377 PolarHBondContact O-N 3.12Å; V374-S377 VanDerWaalsContact O-N 3.11Å; V374-S377 PolarHBondContact O-OG 3.33Å; D375-S377 PolarHBondContact O-N 2.79Å; S377-S380 PolarHBondContact O-N 3.17Å; S377-S380 PolarHBondContact O-OG 3.34Å; S377-T381 PolarHBondContact O-N 2.94Å; S377-T381 PolarHBondContact O-OG1 2.94Å
378E60.7Low62.1Low123 Ų12392.9 Ų92.958%0.57550%0.498SS*.Hα-helixtrans-66.8-41.7176.5-72-176-17800112V374 D375 S380 T381 S382V374-E378 HydrophobicContact CG1-CG 4.4Å; V374-E378 WeakPolarHBondContact O-CG 3.29Å; V374-E378 PolarHBondContact O-N 3.25Å; D375-E378 PolarHBondContact O-N 2.99Å; E378-S380 PolarHBondContact O-N 3.42Å; E378-T381 PolarHBondContact O-N 3.33Å; E378-S382 PolarHBondContact O-N 3.3Å
379L56.5Low60.1Low101 Ų10196.3 Ų96.353%0.52952%0.515SS..Hα-helixtrans-59.3-46.6173.3-97.2125.5000111.7D375 T381 S382 E383D375-L379 WeakPolarHBondContact O-CB 3.47Å; D375-L379 VanDerWaalsContact O-CD1 3.32Å; D375-L379 WeakPolarHBondContact O-CD1 3.34Å; D375-L379 PolarHBondContact O-N 2.88Å; L379-T381 PolarHBondContact O-N 3.3Å; L379-S382 PolarHBondContact O-N 3.3Å; L379-S382 VanDerWaalsContact O-N 3.15Å; L379-S382 PolarHBondContact O-OG 3.24Å; L379-E383 WeakPolarHBondContact O-CG 3.3Å; L379-E383 PolarHBondContact O-N 3.24Å
380S53.8Low58.5Low53 Ų53100.8 Ų100.837%0.37154%0.535SS..Hα-helixtrans-64-29.3177.577.90000113.1S376 S377 E378 K384S376-S380 WeakPolarHBondContact O-CB 3.38Å; S376-S380 PolarHBondContact O-N 3.47Å; S377-S380 PolarHBondContact O-N 3.17Å; S377-S380 PolarHBondContact O-OG 3.34Å; E378-S380 PolarHBondContact O-N 3.42Å; S380-K384 WeakPolarHBondContact O-CG 3.35Å; S380-K384 PolarHBondContact O-N 3.35Å
381T53.1Low56.6Low75 Ų7598.6 Ų98.646%0.4655%0.546SS..Hα-helixtrans-77.4-36.8176.2-42.50000110.4S377 E378 L379 K384 N385S377-T381 PolarHBondContact O-N 2.94Å; S377-T381 PolarHBondContact O-OG1 2.94Å; E378-T381 PolarHBondContact O-N 3.33Å; L379-T381 PolarHBondContact O-N 3.3Å; T381-K384 PolarHBondContact O-N 3.14Å; T381-N385 VanDerWaalsContact O-CG 3.3Å; T381-N385 PolarHBondContact O-N 3.49Å; T381-N385 PolarHBondContact O-ND2 3.16Å
382S52.7Low55Low52 Ų5299.4 Ų99.436%0.36455%0.552SS.*Hα-helixtrans-69.7-36.2175.799.90000112.7E378 L379 N385 K386E378-S382 PolarHBondContact O-N 3.3Å; L379-S382 PolarHBondContact O-N 3.3Å; L379-S382 VanDerWaalsContact O-N 3.15Å; L379-S382 PolarHBondContact O-OG 3.24Å; S382-N385 PolarHBondContact O-N 2.97Å; S382-K386 PolarHBondContact O-N 3.41Å
383E53.5Low53.6Low125 Ų125101.6 Ų101.658%0.58456%0.561SS**Hα-helixtrans-68.1-37.6175.3-74.4179.3160.300111.6L379 N385 K386 A387L379-E383 WeakPolarHBondContact O-CG 3.3Å; L379-E383 PolarHBondContact O-N 3.24Å; E383-N385 VanDerWaalsContact C-N 3.34Å; E383-K386 PolarHBondContact O-N 2.95Å; E383-A387 WeakPolarHBondContact O-CB 3.49Å; E383-A387 PolarHBondContact O-N 3.03Å
384K50.5Low52Low147 Ų147105.3 Ų105.364%0.63958%0.577SS**Hα-helixtrans-65-37171-77.6178.4179.61770112.4S380 T381 I388S380-K384 WeakPolarHBondContact O-CG 3.35Å; S380-K384 PolarHBondContact O-N 3.35Å; T381-K384 PolarHBondContact O-N 3.14Å; K384-I388 WeakPolarHBondContact O-CD1 3.34Å; K384-I388 VanDerWaalsContact O-CG1 3.3Å; K384-I388 WeakPolarHBondContact O-CG1 3.12Å; K384-I388 PolarHBondContact O-N 2.88Å
385N48.3Very low50.5Low96 Ų96109.3 Ų109.351%0.51360%0.596SS.*Hα-helixtrans-72.1-36.5176.9-71.4-15.9000112.3T381 S382 E383 I388 E389T381-N385 VanDerWaalsContact O-CG 3.3Å; T381-N385 PolarHBondContact O-N 3.49Å; T381-N385 PolarHBondContact O-ND2 3.16Å; S382-N385 PolarHBondContact O-N 2.97Å; E383-N385 VanDerWaalsContact C-N 3.34Å; N385-I388 PolarHBondContact O-N 3.43Å; N385-E389 PolarHBondContact O-N 3.26Å
386K49.9Very low49.3Very low137 Ų137111.6 Ų111.660%0.59661%0.613SS**Hα-helixtrans-65.6-37.9172.2-78.1-177.2176.3179.70112.9S382 E383 I388 E389 D390S382-K386 PolarHBondContact O-N 3.41Å; E383-K386 PolarHBondContact O-N 2.95Å; K386-I388 PolarHBondContact O-N 3.05Å; K386-E389 PolarHBondContact O-N 3.25Å; K386-D390 PolarHBondContact O-N 3.36Å
387A49.7Very low48.1Very low71 Ų71117.5 Ų117.559%0.58763%0.633SS**Hα-helixtrans-66.9-21.2175.300000113.6E383E383-A387 WeakPolarHBondContact O-CB 3.49Å; E383-A387 PolarHBondContact O-N 3.03Å
388I50Low47.8Very low116 Ų116120.4 Ų120.460%0.59565%0.651SS**Hα-helixtrans-83.8-32.1174.6-65.9165.7000111K384 N385 K386K384-I388 WeakPolarHBondContact O-CD1 3.34Å; K384-I388 VanDerWaalsContact O-CG1 3.3Å; K384-I388 WeakPolarHBondContact O-CG1 3.12Å; K384-I388 PolarHBondContact O-N 2.88Å; N385-I388 PolarHBondContact O-N 3.43Å; K386-I388 PolarHBondContact O-N 3.05Å
389E45.9Very low46.5Very low153 Ų153119.2 Ų119.272%0.71566%0.663SS**Hα-helixtrans-75.2-34.3175.3-79.1-175.9154.500113.2N385 K386 G391N385-E389 PolarHBondContact O-N 3.26Å; K386-E389 PolarHBondContact O-N 3.25Å; E389-G391 PolarHBondContact O-N 3.47Å
390D48.6Very low45.6Very low149 Ų149119.3 Ų119.380%0.79768%0.677SS**THydrogen-bonded Turntrans-75.6-6.2177.8-77.3-24.3000113.9K386K386-D390 PolarHBondContact O-N 3.36Å
391G44.3Very low44.9Very low63 Ų63127.6 Ų127.665%0.64970%0.702SS**THydrogen-bonded Turntrans-89.8-4.4179.300000115.6E389E389-G391 PolarHBondContact O-N 3.47Å
392Q42.9Very low44.3Very low162 Ų162131.6 Ų131.676%0.75772%0.72SS**SBendtrans-113.859.6-178.4-72.3-173.4-4.800112.1
393N43.8Very low43.8Very low143 Ų143134.4 Ų134.477%0.76574%0.739SS**  trans-160.195155.6-104.6-22000109.7
394N38.5Very low43.2Very low170 Ų170135.8 Ų135.891%0.90979%0.787SS**  trans-149.6129.5146.4-96.6-27.3000110.8
395N37.2Very low42.9Very low154 Ų154135.2 Ų135.282%0.82480%0.795SS**  trans-63146.6-167.8-73.5-44.9000114.1
396V38.4Very low42.6Very low135 Ų135137.3 Ų137.382%0.81881%0.809SS**  trans-74.3131.1163176.90000108.9
397E34.6Very low42.2Very low188 Ų188137.3 Ų137.388%0.87982%0.821SS**  trans-143.8151.3143.9-100.1-164.6173.300111.5
398P51Low41.7Very low116 Ų116141.2 Ų141.275%0.75384%0.835SS**  trans-108.9148.2-16238.3-26.7000113.8
399A33.9Very low41.2Very low98 Ų98142.8 Ų142.881%0.8185%0.85SS**  trans-149.9109.4161.600000108.3
400A36.9Very low40.9Very low102 Ų102142.1 Ų142.184%0.84386%0.859SS**  89.8123.580.300000112.7
401Y39.2Very low40.4Very low228 Ų228141.6 Ų141.689%0.89486%0.864SS**  trans-49.5148.5173.8-85-108.4000114.3
402L39.8Very low40.1Very low159 Ų159147.6 Ų147.683%0.83288%0.88SS**  179.6122113.3-94.2156000113
403S43Very low39.8Very low110 Ų110146.4 Ų146.477%0.76989%0.89SS**  trans18132.4144.356.40000122
404G41.6Very low39.5Very low154 Ų154146.7 Ų146.7100%1.58890%0.902SS**  trans-175.10154.500000109.7

Retrieved 404 of 404 residues in 724.1 ms (Link to these results)