A0A087XTP6_POEFO Loading...

Serine incorporator 2

AlphaFold DB , UniProt , Accession A0A087XTP6, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 457 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	36.4	Very low	37.4	Very low	206 Å²	206	96.9 Å²	96.9	100%	1.015	61%	0.609	S	S	*	*				0	-37.9	0	-70.7	175.7	73.8	0	0	113.4	A3 C4 M5	M1-A3 PolarHBondContact O-N 3Å; M1-C4 PolarHBondContact O-N 2.99Å; M1-M5 PolarHBondContact O-N 3.39Å
2	G	35.7	Very low	38.1	Very low	57 Å²	57	94.1 Å²	94.1	59%	0.588	60%	0.595	S	S	*	*	H	α-helix	trans	-62.2	-35.2	175	0	0	0	0	0	115.5	M5 A6	G2-M5 PolarHBondContact O-N 3.16Å; G2-A6 WeakPolarHBondContact O-CB 3.32Å; G2-A6 PolarHBondContact O-N 2.95Å
3	A	33	Very low	38.7	Very low	71 Å²	71	91.5 Å²	91.5	59%	0.587	58%	0.581	S	S	*	*	H	α-helix	trans	-69.4	-35.1	176.3	0	0	0	0	0	113.3	M1 L7	M1-A3 PolarHBondContact O-N 3Å; A3-L7 WeakPolarHBondContact O-CB 3.16Å; A3-L7 WeakPolarHBondContact O-CD1 3.19Å; A3-L7 WeakPolarHBondContact O-CG 3.41Å; A3-L7 PolarHBondContact O-N 3.19Å
4	C	28.8	Very low	39	Very low	85 Å²	85	88.2 Å²	88.2	57%	0.574	57%	0.566	S	S	*	*	H	α-helix	trans	-70.5	-35.9	174.8	-77.7	0	0	0	0	112.2	M1 L7 C8	M1-C4 PolarHBondContact O-N 2.99Å; C4-L7 PolarHBondContact O-N 2.92Å; C4-C8 WeakPolarHBondContact O-CB 3.47Å; C4-C8 PolarHBondContact O-N 3.02Å; C4-C8 PolarHBondContact O-SG 2.85Å
5	M	36.3	Very low	39.5	Very low	141 Å²	141	87.3 Å²	87.3	70%	0.695	56%	0.564	S	S	*	*	H	α-helix	trans	-71.3	-35.8	174.4	-68.7	-147.2	-67.6	0	0	112.3	M1 G2 C8 S9	M1-M5 PolarHBondContact O-N 3.39Å; G2-M5 PolarHBondContact O-N 3.16Å; M5-C8 PolarHBondContact O-N 2.68Å; M5-S9 PolarHBondContact O-N 2.96Å; M5-S9 PolarHBondContact O-OG 3.41Å
6	A	39.1	Very low	40.1	Very low	51 Å²	51	83.2 Å²	83.2	42%	0.421	54%	0.537	S	S	.	.	H	α-helix	trans	-65.4	-39.3	172	0	0	0	0	0	112.5	G2 S9 L10	G2-A6 WeakPolarHBondContact O-CB 3.32Å; G2-A6 PolarHBondContact O-N 2.95Å; A6-S9 PolarHBondContact O-N 2.99Å; A6-L10 WeakPolarHBondContact O-CB 3.4Å; A6-L10 WeakPolarHBondContact O-CG 3.28Å; A6-L10 PolarHBondContact O-N 3.39Å
7	L	34.1	Very low	40.5	Very low	115 Å²	115	83.2 Å²	83.2	60%	0.602	53%	0.531	S	S	*	.	H	α-helix	trans	-67.3	-38.1	173.7	-83.6	157	0	0	0	112.3	A3 C4 L10 A11	A3-L7 WeakPolarHBondContact O-CB 3.16Å; A3-L7 WeakPolarHBondContact O-CD1 3.19Å; A3-L7 WeakPolarHBondContact O-CG 3.41Å; A3-L7 PolarHBondContact O-N 3.19Å; C4-L7 PolarHBondContact O-N 2.92Å; L7-L10 PolarHBondContact O-N 3.4Å; L7-A11 VanDerWaalsContact O-CB 3.23Å; L7-A11 WeakPolarHBondContact O-CB 3.49Å; L7-A11 PolarHBondContact O-N 3.32Å
8	C	36.2	Very low	40.5	Very low	87 Å²	87	82.2 Å²	82.2	59%	0.588	53%	0.526	S	S	*	.	H	α-helix	trans	-69.1	-37.6	174.1	-73.6	0	0	0	0	112.5	C4 M5 A11 S12	C4-C8 WeakPolarHBondContact O-CB 3.47Å; C4-C8 PolarHBondContact O-N 3.02Å; C4-C8 PolarHBondContact O-SG 2.85Å; M5-C8 PolarHBondContact O-N 2.68Å; C8-A11 PolarHBondContact O-N 2.9Å; C8-S12 VanDerWaalsContact O-CB 3.26Å; C8-S12 WeakPolarHBondContact O-CB 3.34Å; C8-S12 PolarHBondContact O-N 3.02Å
9	S	46.7	Very low	40.8	Very low	71 Å²	71	79.1 Å²	79.1	50%	0.497	51%	0.511	S	S	.	.	H	α-helix	trans	-66.4	-41.2	172.1	-75.4	0	0	0	0	112.2	M5 A6 S12 C13	M5-S9 PolarHBondContact O-N 2.96Å; M5-S9 PolarHBondContact O-OG 3.41Å; A6-S9 PolarHBondContact O-N 2.99Å; S9-S12 PolarHBondContact O-N 3.28Å; S9-C13 WeakPolarHBondContact O-CB 3.4Å; S9-C13 PolarHBondContact O-N 2.91Å; S9-C13 PolarHBondContact O-SG 3.22Å
10	L	41.7	Very low	41	Very low	121 Å²	121	79.1 Å²	79.1	63%	0.634	51%	0.513	S	S	*	.	H	α-helix	trans	-66.6	-39.2	175	-77.4	165.3	0	0	0	112.2	A6 L7 A14	A6-L10 WeakPolarHBondContact O-CB 3.4Å; A6-L10 WeakPolarHBondContact O-CG 3.28Å; A6-L10 PolarHBondContact O-N 3.39Å; L7-L10 PolarHBondContact O-N 3.4Å; L10-A14 VanDerWaalsContact O-CB 3.22Å; L10-A14 WeakPolarHBondContact O-CB 3.46Å; L10-A14 PolarHBondContact O-N 3.33Å
11	A	43	Very low	41.1	Very low	61 Å²	61	77.2 Å²	77.2	50%	0.504	50%	0.504	S	S	.	.	H	α-helix	trans	-68.1	-38.9	175.5	0	0	0	0	0	112.1	L7 C8 A14 S15	L7-A11 VanDerWaalsContact O-CB 3.23Å; L7-A11 WeakPolarHBondContact O-CB 3.49Å; L7-A11 PolarHBondContact O-N 3.32Å; C8-A11 PolarHBondContact O-N 2.9Å; A11-A14 PolarHBondContact O-N 2.95Å; A11-S15 PolarHBondContact O-N 3.21Å; A11-S15 PolarHBondContact O-OG 2.96Å; A11-S15 VanDerWaalsContact O-OG 3.12Å
12	S	45.8	Very low	41.6	Very low	63 Å²	63	68.5 Å²	68.5	44%	0.441	46%	0.463	S	S	.	.	H	α-helix	trans	-70.2	-35.8	177	-150.3	0	0	0	0	112	C8 S9 S15 C16	C8-S12 VanDerWaalsContact O-CB 3.26Å; C8-S12 WeakPolarHBondContact O-CB 3.34Å; C8-S12 PolarHBondContact O-N 3.02Å; S9-S12 PolarHBondContact O-N 3.28Å; S12-S15 WeakPolarHBondContact CA-OG 3.44Å; S12-S15 PolarHBondContact O-OG 2.95Å; S12-C16 PolarHBondContact O-N 3.08Å
13	C	46.3	Very low	42.1	Very low	61 Å²	61	67.2 Å²	67.2	41%	0.412	45%	0.445	S	S	.	.	H	α-helix	trans	-68.6	-38.3	169.5	-71.3	0	0	0	0	112.1	S9 C16 L17	S9-C13 WeakPolarHBondContact O-CB 3.4Å; S9-C13 PolarHBondContact O-N 2.91Å; S9-C13 PolarHBondContact O-SG 3.22Å; C13-C16 PolarHBondContact O-N 3.35Å; C13-L17 WeakPolarHBondContact O-CG 3.31Å; C13-L17 PolarHBondContact O-N 3.44Å
14	A	43.4	Very low	42.7	Very low	45 Å²	45	66.4 Å²	66.4	37%	0.372	43%	0.43	S	S	.	.	H	α-helix	trans	-65.8	-36.9	176.6	0	0	0	0	0	112.3	L10 A11 C16 L17 C18	L10-A14 VanDerWaalsContact O-CB 3.22Å; L10-A14 WeakPolarHBondContact O-CB 3.46Å; L10-A14 PolarHBondContact O-N 3.33Å; A11-A14 PolarHBondContact O-N 2.95Å; A14-C16 VanDerWaalsContact C-N 3.33Å; A14-C16 PolarHBondContact O-N 2.95Å; A14-L17 PolarHBondContact O-N 2.82Å; A14-C18 WeakPolarHBondContact O-CB 3.43Å; A14-C18 PolarHBondContact O-N 3.5Å; A14-C18 PolarHBondContact O-SG 3Å
15	S	46.5	Very low	43.4	Very low	75 Å²	75	67 Å²	67	52%	0.524	43%	0.431	S	S	.	.	H	α-helix	trans	-66.4	-31	172.9	44.8	0	0	0	0	113.6	A11 S12 G19	A11-S15 PolarHBondContact O-N 3.21Å; A11-S15 PolarHBondContact O-OG 2.96Å; A11-S15 VanDerWaalsContact O-OG 3.12Å; S12-S15 WeakPolarHBondContact CA-OG 3.44Å; S12-S15 PolarHBondContact O-OG 2.95Å; S15-G19 PolarHBondContact O-N 3.47Å
16	C	49	Very low	43.8	Very low	21 Å²	21	60.9 Å²	60.9	14%	0.142	40%	0.402	C	S	.	.	H	α-helix	trans	-76.2	-26.2	172.2	-70.5	0	0	0	0	113.2	S12 C13 A14	S12-C16 PolarHBondContact O-N 3.08Å; C13-C16 PolarHBondContact O-N 3.35Å; A14-C16 VanDerWaalsContact C-N 3.33Å; A14-C16 PolarHBondContact O-N 2.95Å
17	L	45.8	Very low	44	Very low	83 Å²	83	61.5 Å²	61.5	44%	0.435	41%	0.413	S	S	.	.	H	α-helix	trans	-80.8	-34.1	176.2	-71.7	163.7	0	0	0	112.2	C13 A14 W132 F133	C13-L17 WeakPolarHBondContact O-CG 3.31Å; C13-L17 PolarHBondContact O-N 3.44Å; A14-L17 PolarHBondContact O-N 2.82Å; L17-W132 HydrophobicContact CD2-CB 3.83Å; L17-W132 HydrophobicContact CD2-CG 4.49Å; L17-F133 WeakPolarHBondContact O-CB 3.35Å; L17-F133 PolarHBondContact O-N 3.21Å
18	C	40.8	Very low	44.5	Very low	66 Å²	66	61.3 Å²	61.3	45%	0.446	42%	0.421	S	S	.	.	H	α-helix	trans	-89.9	-9.6	-177.9	-68.7	0	0	0	0	115	A14 F133	A14-C18 WeakPolarHBondContact O-CB 3.43Å; A14-C18 PolarHBondContact O-N 3.5Å; A14-C18 PolarHBondContact O-SG 3Å; C18-F133 HydrophobicContact CB-CB 4.36Å; C18-F133 VanDerWaalsContact SG-CD2 3.59Å; C18-F133 VanDerWaalsContact SG-CG 3.52Å
19	G	46.4	Very low	44.9	Very low	22 Å²	22	59.6 Å²	59.6	23%	0.227	41%	0.409	C	S	.	.	S	Bend	trans	-86.5	157.7	-179.5	0	0	0	0	0	114.6	S15 A21	S15-G19 PolarHBondContact O-N 3.47Å; G19-A21 PolarHBondContact O-N 3.13Å
20	S	45	Very low	45.1	Very low	79 Å²	79	61.2 Å²	61.2	55%	0.552	42%	0.417	S	S	*	.	S	Bend	trans	-71.9	-10.6	165	46.5	0	0	0	0	112.9
21	A	42.3	Very low	45.7	Very low	41 Å²	41	58.3 Å²	58.3	34%	0.339	41%	0.408	S	S	.	.	S	Bend	trans	-81.2	129.1	175.2	0	0	0	0	0	110	G19 V25	G19-A21 PolarHBondContact O-N 3.13Å; A21-V25 HydrophobicContact CB-CG2 4.25Å
22	P	48	Very low	46.7	Very low	23 Å²	23	57.5 Å²	57.5	15%	0.149	40%	0.398	C	S	.	.			trans	-51.1	174.7	163.6	-21	25.5	0	0	0	111.3	L24	P22-L24 HydrophobicContact CB-CD1 3.89Å; P22-L24 HydrophobicContact CB-CG 3.96Å; P22-L24 HydrophobicContact CG-CD1 3.65Å; P22-L24 HydrophobicContact CG-CG 4.28Å; P22-L24 PolarHBondContact O-N 2.96Å
23	C	46.3	Very low	48.1	Very low	29 Å²	29	57 Å²	57	20%	0.196	39%	0.39	C	S	.	.	G	3₁₀ helix	trans	-57.4	12.8	172.4	-68.1	0	0	0	0	115.2	V25 C26 V37	C23-V25 PolarHBondContact O-N 2.91Å; C23-V25 VanDerWaalsContact O-N 3.08Å; C23-C26 PolarHBondContact O-N 3.26Å; C23-V37 HydrophobicContact CB-CG1 4.36Å
24	L	44.7	Very low	49.5	Very low	55 Å²	55	54.6 Å²	54.6	29%	0.288	37%	0.374	S	S	.	.	G	3₁₀ helix	trans	-53.1	-14.3	172.4	-76.2	165.2	0	0	0	115.3	P22 R376 A377	P22-L24 HydrophobicContact CB-CD1 3.89Å; P22-L24 HydrophobicContact CB-CG 3.96Å; P22-L24 HydrophobicContact CG-CD1 3.65Å; P22-L24 HydrophobicContact CG-CG 4.28Å; P22-L24 PolarHBondContact O-N 2.96Å; L24-R376 HydrophobicContact CD2-CB 3.86Å; L24-R376 WeakPolarHBondContact O-CD 3.38Å; L24-R376 WeakPolarHBondContact O-CG 3.38Å; L24-A377 HydrophobicContact CD2-CB 4.31Å; L24-A377 WeakPolarHBondContact CD2-O 3.44Å
25	V	44	Very low	51.1	Low	96 Å²	96	52.5 Å²	52.5	58%	0.582	36%	0.356	S	S	*	.	G	3₁₀ helix	trans	-118.9	-6.6	-171.6	-161.7	0	0	0	0	113.2	A21 C23 G27	A21-V25 HydrophobicContact CB-CG2 4.25Å; C23-V25 PolarHBondContact O-N 2.91Å; C23-V25 VanDerWaalsContact O-N 3.08Å; V25-G27 PolarHBondContact O-N 3.41Å
26	C	45.2	Very low	52.8	Low	14 Å²	14	49.7 Å²	49.7	10%	0.095	34%	0.336	C	S	.	.			trans	-88.5	110.3	177.9	-159.8	0	0	0	0	110.2	C23 C28 C29	C23-C26 PolarHBondContact O-N 3.26Å; C26-C28 PolarHBondContact O-N 2.72Å; C26-C29 PolarHBondContact O-N 3.12Å
27	G	43	Very low	54.3	Low	64 Å²	64	49.9 Å²	49.9	66%	0.66	34%	0.336	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.2	4.7	175.3	0	0	0	0	0	115.3	V25	V25-G27 PolarHBondContact O-N 3.41Å
28	C	44.6	Very low	56.3	Low	111 Å²	111	46 Å²	46	75%	0.75	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.8	-7.1	175.8	-63.2	0	0	0	0	113.6	C26	C26-C28 PolarHBondContact O-N 2.72Å
29	C	45.3	Very low	58.5	Low	50 Å²	50	43.2 Å²	43.2	34%	0.338	30%	0.296	S	S	.	.	S	Bend	trans	-93.9	129.1	177.8	-79.6	0	0	0	0	110.9	C26	C26-C29 PolarHBondContact O-N 3.12Å
30	P	50	Low	60.5	Low	105 Å²	105	45.2 Å²	45.2	68%	0.682	30%	0.301	S	S	*	.			trans	-57	155.7	166.7	1.7	3.9	0	0	0	110.2	S32	P30-S32 VanDerWaalsContact C-N 3.29Å; P30-S32 PolarHBondContact O-N 3.29Å
31	S	55.1	Low	62.7	Low	61 Å²	61	42.9 Å²	42.9	43%	0.427	28%	0.283	S	S	.	.	S	Bend	trans	-60.6	89.2	173.5	55.9	0	0	0	0	110.2
32	S	63.1	Low	65.1	Low	43 Å²	43	40.9 Å²	40.9	30%	0.301	27%	0.267	S	S	.	.			trans	-118.7	152	-177.7	-166.6	0	0	0	0	109.9	P30 A377 V378	P30-S32 VanDerWaalsContact C-N 3.29Å; P30-S32 PolarHBondContact O-N 3.29Å; S32-A377 VanDerWaalsContact O-CA 3.22Å; S32-A377 WeakPolarHBondContact O-CA 3.48Å; S32-A377 WeakPolarHBondContact O-CB 3.46Å; S32-V378 PolarHBondContact O-N 3.45Å
33	N	74.8	Confident	67.2	Low	53 Å²	53	39.9 Å²	39.9	28%	0.283	26%	0.26	S	S	.	.	B	Isolated β-bridge	trans	-65.7	132.9	179.5	-70.2	-26	0	0	0	110.6	S35 T36 V37	N33-S35 VanDerWaalsContact C-N 3.26Å; N33-S35 PolarHBondContact O-N 3.29Å; N33-T36 PolarHBondContact O-N 3.28Å; N33-V37 PolarHBondContact O-N 2.75Å; N33-V37 VanDerWaalsContact O-N 3.11Å
34	N	75.3	Confident	69.4	Low	11 Å²	11	44.2 Å²	44.2	6%	0.059	28%	0.276	C	S	.	.	H	α-helix	trans	-55.1	-42.7	-178.4	-171.6	33.2	0	0	0	112	T36 V37 T38 A377 V378	N34-T36 VanDerWaalsContact C-N 3.27Å; N34-T36 PolarHBondContact O-N 3.37Å; N34-V37 PolarHBondContact O-N 3.21Å; N34-T38 WeakPolarHBondContact O-CB 3.27Å; N34-T38 PolarHBondContact O-N 3.43Å; N34-T38 PolarHBondContact O-OG1 2.91Å; N34-A377 HydrophobicContact CB-CB 4.49Å; N34-V378 WeakPolarHBondContact CB-O 3.41Å; N34-V378 PolarHBondContact N-O 3.08Å
35	S	78.6	Confident	71.8	Confident	1 Å²	1	42 Å²	42	1%	0.007	27%	0.265	C	S	.	.	H	α-helix	trans	-53.1	-39.5	173.8	52.3	0	0	0	0	113.9	N33 R39 N380 T386	N33-S35 VanDerWaalsContact C-N 3.26Å; N33-S35 PolarHBondContact O-N 3.29Å; S35-R39 VanDerWaalsContact O-CG 3.31Å; S35-R39 WeakPolarHBondContact O-CG 3.41Å; S35-R39 PolarHBondContact O-N 3.47Å; S35-R39 PolarHBondContact O-NE 3.02Å; S35-N380 WeakPolarHBondContact CB-OD1 3.22Å; S35-N380 VanDerWaalsContact OG-CG 3.29Å; S35-N380 PolarHBondContact OG-ND2 3.18Å; S35-N380 PolarHBondContact OG-OD1 2.92Å; S35-T386 WeakPolarHBondContact CB-OG1 3.42Å
36	T	80.6	Confident	74.2	Confident	16 Å²	16	37.5 Å²	37.5	10%	0.098	24%	0.237	C	C	.	.	H	α-helix	trans	-78.1	-41.3	-178.7	-59.1	0	0	0	0	111	N33 N34 T38 R39 L40	N33-T36 PolarHBondContact O-N 3.28Å; N34-T36 VanDerWaalsContact C-N 3.27Å; N34-T36 PolarHBondContact O-N 3.37Å; T36-T38 PolarHBondContact O-N 3.04Å; T36-R39 PolarHBondContact O-N 2.77Å; T36-R39 PolarHBondContact OG1-NH2 3.44Å; T36-L40 HydrophobicContact CG2-CD1 4.25Å; T36-L40 WeakPolarHBondContact O-CG 2.79Å; T36-L40 PolarHBondContact O-N 3.21Å
37	V	82.3	Confident	76.6	Confident	24 Å²	24	38.6 Å²	38.6	15%	0.145	24%	0.242	C	C	.	.	H	α-helix	trans	-59.3	-47.6	174.3	177.7	0	0	0	0	110.6	C23 N33 N34 R39 L40 V41	C23-V37 HydrophobicContact CB-CG1 4.36Å; N33-V37 PolarHBondContact O-N 2.75Å; N33-V37 VanDerWaalsContact O-N 3.11Å; N34-V37 PolarHBondContact O-N 3.21Å; V37-R39 PolarHBondContact O-N 2.95Å; V37-L40 WeakPolarHBondContact O-CB 3.41Å; V37-L40 PolarHBondContact O-N 3.4Å; V37-V41 HydrophobicContact CG1-CG2 4.39Å; V37-V41 WeakPolarHBondContact O-CG2 3.35Å; V37-V41 PolarHBondContact O-N 3.19Å
38	T	86.3	Confident	79	Confident	1 Å²	1	38.3 Å²	38.3	1%	0.006	23%	0.225	C	C	.	.	H	α-helix	trans	-57.8	-46.1	177.8	-70.8	0	0	0	0	112.3	N34 T36 L40 V41 F42 Q128 N129 W132	N34-T38 WeakPolarHBondContact O-CB 3.27Å; N34-T38 PolarHBondContact O-N 3.43Å; N34-T38 PolarHBondContact O-OG1 2.91Å; T36-T38 PolarHBondContact O-N 3.04Å; T38-L40 VanDerWaalsContact C-N 3.35Å; T38-L40 PolarHBondContact O-N 2.89Å; T38-V41 PolarHBondContact O-N 3.43Å; T38-F42 HydrophobicContact CG2-CD2 3.9Å; T38-F42 HydrophobicContact CG2-CE2 3.86Å; T38-F42 WeakPolarHBondContact O-CD2 3.32Å; T38-F42 PolarHBondContact O-N 3.32Å; T38-F42 VanDerWaalsContact O-N 3.08Å; T38-Q128 HydrophobicContact CG2-CG 4.02Å; T38-N129 WeakPolarHBondContact CB-OD1 3.34Å; T38-N129 WeakPolarHBondContact CG2-OD1 3.39Å; T38-N129 PolarHBondContact OG1-OD1 3.36Å; T38-W132 HydrophobicContact CG2-CH2 4Å; T38-W132 HydrophobicContact CG2-CZ2 4.48Å
39	R	88.1	Confident	81.4	Confident	8 Å²	8	33 Å²	33	3%	0.03	19%	0.189	C	C	.	.	H	α-helix	trans	-62.2	-41	176.6	-72.4	-176.5	-64.2	159.5	-0.1	112.3	S35 T36 V37 F42 S43 A341 S342 R344 Y387 F392	S35-R39 VanDerWaalsContact O-CG 3.31Å; S35-R39 WeakPolarHBondContact O-CG 3.41Å; S35-R39 PolarHBondContact O-N 3.47Å; S35-R39 PolarHBondContact O-NE 3.02Å; T36-R39 PolarHBondContact O-N 2.77Å; T36-R39 PolarHBondContact OG1-NH2 3.44Å; V37-R39 PolarHBondContact O-N 2.95Å; R39-F42 PolarHBondContact O-N 3.19Å; R39-S43 WeakPolarHBondContact O-CB 3.5Å; R39-S43 PolarHBondContact O-N 2.96Å; R39-S43 PolarHBondContact O-OG 2.89Å; R39-A341 PolarHBondContact NH1-O 3.22Å; R39-A341 VanDerWaalsContact NH1-O 3.16Å; R39-S342 PolarHBondContact NE-O 3.45Å; R39-S342 PolarHBondContact NH2-O 3.3Å; R39-R344 PolarHBondContact NH1-O 2.7Å; R39-R344 PolarHBondContact NH2-O 3.3Å; R39-Y387 HydrophobicContact CG-CE1 3.96Å; R39-Y387 HydrophobicContact CG-CE2 3.89Å; R39-F392 HydrophobicContact CB-CE1 4.25Å; R39-F392 HydrophobicContact CB-CE2 3.89Å; R39-F392 HydrophobicContact CB-CZ 3.63Å; R39-F392 HydrophobicContact CG-CD1 4.31Å; R39-F392 HydrophobicContact CG-CD2 4.09Å; R39-F392 HydrophobicContact CG-CE1 3.98Å; R39-F392 HydrophobicContact CG-CE2 3.74Å; R39-F392 HydrophobicContact CG-CG 4.36Å; R39-F392 HydrophobicContact CG-CZ 3.69Å
40	L	88.7	Confident	83.8	Confident	64 Å²	64	31 Å²	31	34%	0.335	18%	0.175	S	C	.	.	H	α-helix	trans	-63.6	-41	175.8	-73.7	172.8	0	0	0	112.2	T36 V37 T38 S43 F44 I343	T36-L40 HydrophobicContact CG2-CD1 4.25Å; T36-L40 WeakPolarHBondContact O-CG 2.79Å; T36-L40 PolarHBondContact O-N 3.21Å; V37-L40 WeakPolarHBondContact O-CB 3.41Å; V37-L40 PolarHBondContact O-N 3.4Å; T38-L40 VanDerWaalsContact C-N 3.35Å; T38-L40 PolarHBondContact O-N 2.89Å; L40-S43 WeakPolarHBondContact O-CB 3.42Å; L40-S43 PolarHBondContact O-N 2.89Å; L40-F44 WeakPolarHBondContact O-CB 3.44Å; L40-F44 PolarHBondContact O-N 3.47Å; L40-I343 HydrophobicContact CD2-CG1 3.94Å
41	V	90.4	Very high	85.9	Confident	30 Å²	30	32 Å²	32	18%	0.182	17%	0.173	C	C	.	.	H	α-helix	trans	-67.2	-42.4	178.4	179	0	0	0	0	111.7	V37 T38 S43 F44 F45 W132	V37-V41 HydrophobicContact CG1-CG2 4.39Å; V37-V41 WeakPolarHBondContact O-CG2 3.35Å; V37-V41 PolarHBondContact O-N 3.19Å; T38-V41 PolarHBondContact O-N 3.43Å; V41-S43 VanDerWaalsContact C-N 3.31Å; V41-S43 PolarHBondContact O-N 3.47Å; V41-F44 WeakPolarHBondContact O-CB 3.37Å; V41-F44 PolarHBondContact O-N 3.28Å; V41-F45 HydrophobicContact CG1-CE1 4.47Å; V41-F45 HydrophobicContact CG1-CZ 4.46Å; V41-F45 PolarHBondContact O-N 3.42Å; V41-W132 HydrophobicContact CB-CE3 4.2Å; V41-W132 HydrophobicContact CB-CH2 3.69Å; V41-W132 HydrophobicContact CB-CZ2 4.13Å; V41-W132 HydrophobicContact CB-CZ3 3.75Å; V41-W132 HydrophobicContact CG1-CD2 3.78Å; V41-W132 HydrophobicContact CG1-CE3 3.32Å; V41-W132 HydrophobicContact CG1-CH2 3.78Å; V41-W132 HydrophobicContact CG1-CZ2 4.21Å; V41-W132 HydrophobicContact CG1-CZ3 3.33Å; V41-W132 HydrophobicContact CG2-CH2 4.41Å; V41-W132 HydrophobicContact CG2-CZ2 4.37Å
42	F	93.1	Very high	87.7	Confident	0 Å²	0	31.6 Å²	31.6	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-65.4	-35.7	174	-82	-67.3	0	0	0	112.6	T38 R39 F44 F45 L46 F106 F107 F110 W132 K135 F392 H393 L396	T38-F42 HydrophobicContact CG2-CD2 3.9Å; T38-F42 HydrophobicContact CG2-CE2 3.86Å; T38-F42 WeakPolarHBondContact O-CD2 3.32Å; T38-F42 PolarHBondContact O-N 3.32Å; T38-F42 VanDerWaalsContact O-N 3.08Å; R39-F42 PolarHBondContact O-N 3.19Å; F42-F44 VanDerWaalsContact C-N 3.32Å; F42-F45 HydrophobicContact CD1-CD2 4.26Å; F42-F45 WeakPolarHBondContact O-CB 3.39Å; F42-F45 PolarHBondContact O-N 3.5Å; F42-L46 PolarHBondContact O-N 2.91Å; F42-F106 HydrophobicContact CD1-CE1 4.27Å; F42-F106 HydrophobicContact CE1-CE1 4.25Å; F42-F106 HydrophobicContact CE1-CZ 4.18Å; F42-F107 HydrophobicContact CB-CE1 4.48Å; F42-F107 HydrophobicContact CD1-CE1 4.16Å; F42-F110 HydrophobicContact CE1-CD1 4.35Å; F42-F110 HydrophobicContact CE1-CG 4.39Å; F42-F110 HydrophobicContact CZ-CD1 4.13Å; F42-F110 HydrophobicContact CZ-CE1 4.28Å; F42-W132 HydrophobicContact CD2-CH2 4.03Å; F42-W132 HydrophobicContact CD2-CZ3 4.03Å; F42-W132 HydrophobicContact CE1-CZ3 4.39Å; F42-W132 AromaticContact CE2-CH2 3.86Å; F42-W132 HydrophobicContact CE2-CH2 3.86Å; F42-W132 AromaticContact CE2-CZ3 3.83Å; F42-W132 HydrophobicContact CE2-CZ3 3.83Å; F42-W132 HydrophobicContact CG-CZ3 4.39Å; F42-W132 HydrophobicContact CZ-CH2 4.47Å; F42-W132 HydrophobicContact CZ-CZ3 4.03Å; F42-K135 HydrophobicContact CE1-CD 4.16Å; F42-K135 HydrophobicContact CZ-CD 3.98Å; F42-F392 HydrophobicContact CB-CE1 3.88Å; F42-F392 HydrophobicContact CB-CZ 4.36Å; F42-F392 HydrophobicContact CD2-CE1 4.45Å; F42-F392 HydrophobicContact CG-CE1 4.47Å; F42-H393 AromaticContact CD1-CE1 3.68Å; F42-H393 AromaticContact CD2-CE1 3.66Å; F42-H393 AromaticContact CE1-CE1 3.53Å; F42-H393 AromaticContact CE2-CE1 3.52Å; F42-H393 AromaticContact CE2-NE2 3.96Å; F42-H393 AromaticContact CG-CE1 3.74Å; F42-H393 AromaticContact CZ-CE1 3.45Å; F42-H393 VanDerWaalsContact CZ-CE1 3.45Å; F42-H393 WeakPolarHBondContact CZ-CE1 3.22Å; F42-H393 AromaticContact CZ-NE2 3.98Å; F42-L396 HydrophobicContact CB-CD1 3.77Å
43	S	91.7	Very high	89.1	Confident	1 Å²	1	29.5 Å²	29.5	1%	0.007	15%	0.153	C	C	.	.	H	α-helix	trans	-63.4	-41.6	171.8	-56	0	0	0	0	111	R39 L40 V41 F45 L46 L47 S342	R39-S43 WeakPolarHBondContact O-CB 3.5Å; R39-S43 PolarHBondContact O-N 2.96Å; R39-S43 PolarHBondContact O-OG 2.89Å; L40-S43 WeakPolarHBondContact O-CB 3.42Å; L40-S43 PolarHBondContact O-N 2.89Å; V41-S43 VanDerWaalsContact C-N 3.31Å; V41-S43 PolarHBondContact O-N 3.47Å; S43-F45 VanDerWaalsContact C-N 3.3Å; S43-F45 PolarHBondContact O-N 3.46Å; S43-L46 WeakPolarHBondContact O-CB 3.29Å; S43-L46 PolarHBondContact O-N 3.38Å; S43-L46 VanDerWaalsContact O-N 3.1Å; S43-L47 VanDerWaalsContact O-CG 3.31Å; S43-L47 WeakPolarHBondContact O-CG 3.48Å; S43-L47 PolarHBondContact O-N 3.47Å; S43-S342 WeakPolarHBondContact OG-CB 3.49Å; S43-S342 PolarHBondContact OG-OG 2.9Å
44	F	92	Very high	89.9	Confident	120 Å²	120	28.3 Å²	28.3	53%	0.526	15%	0.147	S	C	.	.	H	α-helix	trans	-59.6	-38.3	174.7	174	-98.7	0	0	0	112.2	L40 V41 F42 L46 L47 L48	L40-F44 WeakPolarHBondContact O-CB 3.44Å; L40-F44 PolarHBondContact O-N 3.47Å; V41-F44 WeakPolarHBondContact O-CB 3.37Å; V41-F44 PolarHBondContact O-N 3.28Å; F42-F44 VanDerWaalsContact C-N 3.32Å; F44-L46 PolarHBondContact O-N 2.89Å; F44-L47 PolarHBondContact O-N 3.34Å; F44-L48 HydrophobicContact CE1-CD2 4.48Å; F44-L48 VanDerWaalsContact O-CB 3.3Å; F44-L48 WeakPolarHBondContact O-CB 3.39Å; F44-L48 PolarHBondContact O-N 3.5Å
45	F	95	Very high	90.5	Very high	10 Å²	10	31.4 Å²	31.4	4%	0.044	16%	0.163	C	C	.	.	H	α-helix	trans	-61.5	-42.1	172.3	-71.7	-9.9	0	0	0	112.7	V41 F42 S43 L48 G49 F106 F107 W132 K135 F136 L139	V41-F45 HydrophobicContact CG1-CE1 4.47Å; V41-F45 HydrophobicContact CG1-CZ 4.46Å; V41-F45 PolarHBondContact O-N 3.42Å; F42-F45 HydrophobicContact CD1-CD2 4.26Å; F42-F45 WeakPolarHBondContact O-CB 3.39Å; F42-F45 PolarHBondContact O-N 3.5Å; S43-F45 VanDerWaalsContact C-N 3.3Å; S43-F45 PolarHBondContact O-N 3.46Å; F45-L48 PolarHBondContact O-N 2.77Å; F45-G49 PolarHBondContact O-N 3.13Å; F45-F106 HydrophobicContact CD2-CE1 4.01Å; F45-F106 AromaticContact CD2-CZ 3.88Å; F45-F106 HydrophobicContact CD2-CZ 3.88Å; F45-F106 HydrophobicContact CE2-CZ 4.21Å; F45-F107 HydrophobicContact CB-CZ 4.36Å; F45-W132 HydrophobicContact CE2-CE3 4.26Å; F45-W132 HydrophobicContact CZ-CE3 4.24Å; F45-K135 HydrophobicContact CE2-CB 3.89Å; F45-K135 HydrophobicContact CZ-CB 4.45Å; F45-F136 HydrophobicContact CE1-CD2 4.45Å; F45-F136 HydrophobicContact CZ-CB 4.26Å; F45-L139 HydrophobicContact CB-CD2 4.43Å
46	L	95.8	Very high	90.8	Very high	0 Å²	0	32.7 Å²	32.7	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-63	-43.5	174.4	179.1	67	0	0	0	111.4	F42 S43 F44 G49 T50 M103 F107 F334 T338 L396 A399	F42-L46 PolarHBondContact O-N 2.91Å; S43-L46 WeakPolarHBondContact O-CB 3.29Å; S43-L46 PolarHBondContact O-N 3.38Å; S43-L46 VanDerWaalsContact O-N 3.1Å; F44-L46 PolarHBondContact O-N 2.89Å; L46-G49 PolarHBondContact O-N 2.94Å; L46-T50 WeakPolarHBondContact O-CB 3.35Å; L46-T50 PolarHBondContact O-N 3.37Å; L46-T50 PolarHBondContact O-OG1 3.38Å; L46-M103 HydrophobicContact CD1-SD 4.24Å; L46-F107 HydrophobicContact CB-CE2 3.92Å; L46-F107 HydrophobicContact CB-CZ 3.79Å; L46-F107 HydrophobicContact CD1-CE2 3.82Å; L46-F107 HydrophobicContact CG-CE2 4.44Å; L46-F334 HydrophobicContact CD2-CE2 4.31Å; L46-F334 HydrophobicContact CD2-CZ 3.71Å; L46-F334 HydrophobicContact CG-CZ 4.08Å; L46-T338 HydrophobicContact CD2-CG2 4.2Å; L46-L396 HydrophobicContact CD2-CD2 3.71Å; L46-A399 HydrophobicContact CD2-CB 3.62Å
47	L	94.6	Very high	90.9	Very high	38 Å²	38	32.6 Å²	32.6	20%	0.199	17%	0.168	C	C	.	.	H	α-helix	trans	-64.6	-44.4	177.7	-65.9	-172.5	0	0	0	111.8	S43 F44 G49 T50 M51 F334 L335	S43-L47 VanDerWaalsContact O-CG 3.31Å; S43-L47 WeakPolarHBondContact O-CG 3.48Å; S43-L47 PolarHBondContact O-N 3.47Å; F44-L47 PolarHBondContact O-N 3.34Å; L47-G49 VanDerWaalsContact C-N 3.34Å; L47-G49 PolarHBondContact O-N 3.17Å; L47-T50 CarbonylContact O-C 3.6Å; L47-T50 WeakPolarHBondContact O-CB 3.31Å; L47-T50 PolarHBondContact O-N 3.14Å; L47-M51 WeakPolarHBondContact O-CG 3.46Å; L47-M51 PolarHBondContact O-N 3.28Å; L47-F334 HydrophobicContact CD2-CE1 4.19Å; L47-L335 HydrophobicContact CD2-CD2 3.17Å; L47-L335 HydrophobicContact CG-CD2 4.44Å
48	L	94.6	Very high	90.8	Very high	57 Å²	57	34.7 Å²	34.7	30%	0.298	18%	0.178	S	C	.	.	H	α-helix	trans	-58.4	-47.3	176.2	179.3	63.8	0	0	0	110.8	F44 F45 T50 M51 V52 F136	F44-L48 HydrophobicContact CE1-CD2 4.48Å; F44-L48 VanDerWaalsContact O-CB 3.3Å; F44-L48 WeakPolarHBondContact O-CB 3.39Å; F44-L48 PolarHBondContact O-N 3.5Å; F45-L48 PolarHBondContact O-N 2.77Å; L48-T50 VanDerWaalsContact C-N 3.32Å; L48-T50 PolarHBondContact O-N 3.38Å; L48-M51 PolarHBondContact O-N 2.84Å; L48-V52 WeakPolarHBondContact O-CG2 3.49Å; L48-V52 PolarHBondContact O-N 3.41Å; L48-F136 HydrophobicContact CD2-CE2 3.87Å
49	G	95.2	Very high	90.1	Very high	1 Å²	1	39 Å²	39	1%	0.01	21%	0.206	C	C	.	.	H	α-helix	trans	-68	-31.5	177.8	0	0	0	0	0	113.6	F45 L46 L47 S53 M103	F45-G49 PolarHBondContact O-N 3.13Å; L46-G49 PolarHBondContact O-N 2.94Å; L47-G49 VanDerWaalsContact C-N 3.34Å; L47-G49 PolarHBondContact O-N 3.17Å; G49-S53 WeakPolarHBondContact O-CB 3.39Å; G49-S53 PolarHBondContact O-N 2.8Å; G49-S53 PolarHBondContact O-OG 3.01Å; G49-M103 VanDerWaalsContact CA-SD 3.52Å
50	T	94.7	Very high	89.2	Confident	6 Å²	6	40.9 Å²	40.9	4%	0.037	23%	0.228	C	C	.	.	H	α-helix	trans	-65.3	-44.2	170.6	-58.3	0	0	0	0	111.2	L46 L47 L48 V52 S53 V54 L331 I403	L46-T50 WeakPolarHBondContact O-CB 3.35Å; L46-T50 PolarHBondContact O-N 3.37Å; L46-T50 PolarHBondContact O-OG1 3.38Å; L47-T50 CarbonylContact O-C 3.6Å; L47-T50 WeakPolarHBondContact O-CB 3.31Å; L47-T50 PolarHBondContact O-N 3.14Å; L48-T50 VanDerWaalsContact C-N 3.32Å; L48-T50 PolarHBondContact O-N 3.38Å; T50-V52 PolarHBondContact O-N 2.92Å; T50-S53 WeakPolarHBondContact O-CB 3.35Å; T50-S53 PolarHBondContact O-N 3.26Å; T50-S53 VanDerWaalsContact O-N 3.15Å; T50-V54 WeakPolarHBondContact O-CG2 3.22Å; T50-V54 PolarHBondContact O-N 3.26Å; T50-L331 HydrophobicContact CG2-CD1 3.93Å; T50-I403 HydrophobicContact CG2-CD1 4.08Å; T50-I403 HydrophobicContact CG2-CG1 4.28Å; T50-I403 HydrophobicContact CG2-CG2 3.85Å
51	M	93.9	Very high	88.5	Confident	128 Å²	128	41 Å²	41	63%	0.631	23%	0.228	S	C	*	.	H	α-helix	trans	-61.6	-44.1	176	-70.2	-158	81.5	0	0	111.6	L47 L48 S53 V54 I55	L47-M51 WeakPolarHBondContact O-CG 3.46Å; L47-M51 PolarHBondContact O-N 3.28Å; L48-M51 PolarHBondContact O-N 2.84Å; M51-S53 VanDerWaalsContact C-N 3.29Å; M51-S53 PolarHBondContact O-N 3Å; M51-V54 PolarHBondContact O-N 3.25Å; M51-I55 VanDerWaalsContact O-CG1 3.28Å; M51-I55 WeakPolarHBondContact O-CG1 3.37Å; M51-I55 PolarHBondContact O-N 2.86Å
52	V	93.1	Very high	87.5	Confident	51 Å²	51	41.7 Å²	41.7	31%	0.309	23%	0.229	S	C	.	.	H	α-helix	trans	-59.1	-42.2	173.9	171.6	0	0	0	0	110.9	L48 T50 I55 M56 M99	L48-V52 WeakPolarHBondContact O-CG2 3.49Å; L48-V52 PolarHBondContact O-N 3.41Å; T50-V52 PolarHBondContact O-N 2.92Å; V52-I55 WeakPolarHBondContact O-CB 3.35Å; V52-I55 PolarHBondContact O-N 3.49Å; V52-M56 HydrophobicContact CG1-CE 3.62Å; V52-M56 HydrophobicContact CG1-SD 4.29Å; V52-M56 WeakPolarHBondContact O-CG 3.24Å; V52-M56 PolarHBondContact O-N 3.49Å; V52-M99 HydrophobicContact CB-CE 4.2Å; V52-M99 HydrophobicContact CG1-CE 4.21Å; V52-M99 HydrophobicContact CG1-CG 4.4Å; V52-M99 HydrophobicContact CG1-SD 4.2Å
53	S	93.1	Very high	86.3	Confident	0 Å²	0	45.8 Å²	45.8	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-64	-40.6	177.2	-57.5	0	0	0	0	112.5	G49 T50 M51 I55 M56 I57 V96 M99	G49-S53 WeakPolarHBondContact O-CB 3.39Å; G49-S53 PolarHBondContact O-N 2.8Å; G49-S53 PolarHBondContact O-OG 3.01Å; T50-S53 WeakPolarHBondContact O-CB 3.35Å; T50-S53 PolarHBondContact O-N 3.26Å; T50-S53 VanDerWaalsContact O-N 3.15Å; M51-S53 VanDerWaalsContact C-N 3.29Å; M51-S53 PolarHBondContact O-N 3Å; S53-I55 VanDerWaalsContact C-N 3.34Å; S53-M56 PolarHBondContact O-N 2.93Å; S53-I57 PolarHBondContact O-N 2.92Å; S53-V96 VanDerWaalsContact O-CG2 3.28Å; S53-V96 WeakPolarHBondContact O-CG2 3.41Å; S53-M99 VanDerWaalsContact OG-CG 3.24Å; S53-M99 WeakPolarHBondContact OG-CG 3.35Å
54	V	90.8	Very high	85.3	Confident	28 Å²	28	50.6 Å²	50.6	17%	0.17	28%	0.276	C	S	.	.	H	α-helix	trans	-62	-43.6	173.2	169.8	0	0	0	0	110.6	T50 M51 M56 I57 L58 W323 L407	T50-V54 WeakPolarHBondContact O-CG2 3.22Å; T50-V54 PolarHBondContact O-N 3.26Å; M51-V54 PolarHBondContact O-N 3.25Å; V54-M56 VanDerWaalsContact C-N 3.28Å; V54-M56 PolarHBondContact O-N 3.49Å; V54-I57 PolarHBondContact O-N 3.08Å; V54-I57 VanDerWaalsContact O-N 3.15Å; V54-L58 PolarHBondContact O-N 2.88Å; V54-W323 HydrophobicContact CG1-CZ2 3.86Å; V54-W323 HydrophobicContact CG2-CZ2 4.2Å; V54-L407 HydrophobicContact CG2-CD1 4.16Å; V54-L407 HydrophobicContact CG2-CD2 3.79Å
55	I	88.8	Confident	84.2	Confident	76 Å²	76	45.5 Å²	45.5	39%	0.39	25%	0.254	S	S	.	.	H	α-helix	trans	-61.3	-37.1	177.5	-68.9	164.6	0	0	0	111.5	M51 V52 S53 I57 L58 M61	M51-I55 VanDerWaalsContact O-CG1 3.28Å; M51-I55 WeakPolarHBondContact O-CG1 3.37Å; M51-I55 PolarHBondContact O-N 2.86Å; V52-I55 WeakPolarHBondContact O-CB 3.35Å; V52-I55 PolarHBondContact O-N 3.49Å; S53-I55 VanDerWaalsContact C-N 3.34Å; I55-I57 PolarHBondContact O-N 3.43Å; I55-L58 HydrophobicContact CG1-CD1 4.3Å; I55-L58 WeakPolarHBondContact O-CB 3.02Å; I55-L58 PolarHBondContact O-N 2.94Å; I55-M61 HydrophobicContact CG2-CE 3.72Å
56	M	85.2	Confident	82.8	Confident	27 Å²	27	51.3 Å²	51.3	13%	0.133	28%	0.276	C	S	.	.	H	α-helix	trans	-65.8	-24.3	177.7	-72.4	172.3	174.8	0	0	113.8	V52 S53 V54 L65 V96 M99 F147	V52-M56 HydrophobicContact CG1-CE 3.62Å; V52-M56 HydrophobicContact CG1-SD 4.29Å; V52-M56 WeakPolarHBondContact O-CG 3.24Å; V52-M56 PolarHBondContact O-N 3.49Å; S53-M56 PolarHBondContact O-N 2.93Å; V54-M56 VanDerWaalsContact C-N 3.28Å; V54-M56 PolarHBondContact O-N 3.49Å; M56-L65 HydrophobicContact CB-CD1 4.41Å; M56-L65 WeakPolarHBondContact O-CD1 3.36Å; M56-V96 HydrophobicContact CB-CG2 4.37Å; M56-M99 HydrophobicContact SD-CB 4.11Å; M56-F147 HydrophobicContact CE-CE2 4.01Å; M56-F147 HydrophobicContact CE-CZ 3.5Å; M56-F147 HydrophobicContact SD-CZ 4.02Å
57	I	81	Confident	81.6	Confident	14 Å²	14	58.4 Å²	58.4	7%	0.072	31%	0.307	C	S	.	.	H	α-helix	trans	-94.2	-11.8	177.4	-65	171.4	0	0	0	111.4	S53 V54 I55 Y93 V96 W322 L407	S53-I57 PolarHBondContact O-N 2.92Å; V54-I57 PolarHBondContact O-N 3.08Å; V54-I57 VanDerWaalsContact O-N 3.15Å; I55-I57 PolarHBondContact O-N 3.43Å; I57-Y93 HydrophobicContact CD1-CD1 3.82Å; I57-Y93 HydrophobicContact CD1-CE1 4.04Å; I57-Y93 HydrophobicContact CG1-CD1 4.16Å; I57-Y93 HydrophobicContact CG1-CE1 4.49Å; I57-Y93 HydrophobicContact CG2-CE1 4.22Å; I57-V96 HydrophobicContact CD1-CB 4.15Å; I57-V96 HydrophobicContact CD1-CG2 3.33Å; I57-V96 HydrophobicContact CG1-CG2 3.54Å; I57-W322 PolarHBondContact O-NE1 3.01Å; I57-L407 HydrophobicContact CD1-CB 3.89Å; I57-L407 VanDerWaalsContact CD1-O 3.31Å; I57-L407 WeakPolarHBondContact CD1-O 3.46Å
58	L	80.4	Confident	80.2	Confident	68 Å²	68	59.1 Å²	59.1	36%	0.356	31%	0.311	S	S	.	.	S	Bend	trans	-60.8	137.5	179.8	-78.4	170.3	0	0	0	112	V54 I55 G60 M61 W322	V54-L58 PolarHBondContact O-N 2.88Å; I55-L58 HydrophobicContact CG1-CD1 4.3Å; I55-L58 WeakPolarHBondContact O-CB 3.02Å; I55-L58 PolarHBondContact O-N 2.94Å; L58-G60 PolarHBondContact O-N 3.12Å; L58-M61 WeakPolarHBondContact O-CB 3.4Å; L58-M61 PolarHBondContact O-N 3.3Å; L58-W322 HydrophobicContact CD2-CH2 3.94Å; L58-W322 HydrophobicContact CD2-CZ2 3.34Å; L58-W322 HydrophobicContact CG-CZ2 4.32Å
59	P	71.7	Confident	78.4	Confident	92 Å²	92	61.4 Å²	61.4	60%	0.597	33%	0.329	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.9	132.9	177.2	26.7	-33.9	0	0	0	109.8
60	G	69.2	Low	76.6	Confident	48 Å²	48	62.7 Å²	62.7	50%	0.495	34%	0.342	S	S	.	.	T	Hydrogen-bonded Turn	trans	103	-24.5	-176.7	0	0	0	0	0	115	L58 E62 T63	L58-G60 PolarHBondContact O-N 3.12Å; G60-E62 PolarHBondContact O-N 2.8Å; G60-T63 PolarHBondContact O-OG1 3.35Å; G60-T63 VanDerWaalsContact O-OG1 3.05Å
61	M	75.1	Confident	74.9	Confident	66 Å²	66	62.5 Å²	62.5	33%	0.325	34%	0.34	S	S	.	.	T	Hydrogen-bonded Turn	trans	-70.7	-21	175.5	-166.1	55	62.8	0	0	112.8	I55 L58 T63 Q64 L65	I55-M61 HydrophobicContact CG2-CE 3.72Å; L58-M61 WeakPolarHBondContact O-CB 3.4Å; L58-M61 PolarHBondContact O-N 3.3Å; M61-T63 PolarHBondContact O-N 3.32Å; M61-Q64 PolarHBondContact O-N 2.71Å; M61-Q64 HydrophobicContact SD-CB 4.23Å; M61-Q64 HydrophobicContact SD-CG 4.37Å; M61-L65 HydrophobicContact CB-CD1 4.47Å; M61-L65 HydrophobicContact CG-CD1 3.97Å; M61-L65 HydrophobicContact CG-CG 4.12Å; M61-L65 PolarHBondContact O-N 2.94Å
62	E	67.8	Low	73.2	Confident	44 Å²	44	58.7 Å²	58.7	21%	0.206	33%	0.326	C	S	.	.	H	α-helix	trans	-52.8	-38	178.8	-61.1	162.6	179.7	0	0	112.5	G60 Q64 L65 R66 D88	G60-E62 PolarHBondContact O-N 2.8Å; E62-Q64 VanDerWaalsContact C-N 3.26Å; E62-Q64 PolarHBondContact O-N 3.38Å; E62-L65 PolarHBondContact O-N 3.3Å; E62-R66 WeakPolarHBondContact O-CB 3.17Å; E62-R66 WeakPolarHBondContact O-CG 3.3Å; E62-R66 PolarHBondContact O-N 2.84Å; E62-D88 HydrophobicContact CG-CB 4.14Å; E62-D88 VanDerWaalsContact OE2-CB 3.25Å; E62-D88 WeakPolarHBondContact OE2-CB 3.23Å
63	T	67.8	Low	71.2	Confident	86 Å²	86	64.3 Å²	64.3	53%	0.528	35%	0.349	S	S	.	.	H	α-helix	trans	-63.8	-30.4	179	60.4	0	0	0	0	113.2	G60 M61	G60-T63 PolarHBondContact O-OG1 3.35Å; G60-T63 VanDerWaalsContact O-OG1 3.05Å; M61-T63 PolarHBondContact O-N 3.32Å
64	Q	71.3	Confident	69	Low	103 Å²	103	66.5 Å²	66.5	48%	0.481	37%	0.372	S	S	.	.	H	α-helix	trans	-85.4	-40.1	176	-56.9	-55.9	-30.3	0	0	111	M61 E62 R66 K67	M61-Q64 PolarHBondContact O-N 2.71Å; M61-Q64 HydrophobicContact SD-CB 4.23Å; M61-Q64 HydrophobicContact SD-CG 4.37Å; E62-Q64 VanDerWaalsContact C-N 3.26Å; E62-Q64 PolarHBondContact O-N 3.38Å; Q64-R66 VanDerWaalsContact C-N 3.34Å; Q64-R66 PolarHBondContact O-N 3.48Å; Q64-K67 WeakPolarHBondContact O-CB 3.26Å; Q64-K67 PolarHBondContact O-N 3.1Å
65	L	69.3	Low	66.7	Low	12 Å²	12	68.2 Å²	68.2	6%	0.063	40%	0.395	C	S	.	.	H	α-helix	trans	-67.6	-32.4	180	-66.8	170.6	0	0	0	112.7	M56 M61 E62 K67 I68 V91	M56-L65 HydrophobicContact CB-CD1 4.41Å; M56-L65 WeakPolarHBondContact O-CD1 3.36Å; M61-L65 HydrophobicContact CB-CD1 4.47Å; M61-L65 HydrophobicContact CG-CD1 3.97Å; M61-L65 HydrophobicContact CG-CG 4.12Å; M61-L65 PolarHBondContact O-N 2.94Å; E62-L65 PolarHBondContact O-N 3.3Å; L65-K67 PolarHBondContact O-N 3.12Å; L65-K67 VanDerWaalsContact O-N 3.15Å; L65-I68 HydrophobicContact CD2-CD1 4.09Å; L65-I68 WeakPolarHBondContact O-CB 3.34Å; L65-I68 PolarHBondContact O-N 2.92Å; L65-V91 HydrophobicContact CB-CG1 3.46Å; L65-V91 VanDerWaalsContact CB-CG1 3.46Å; L65-V91 HydrophobicContact CD1-CG1 4.26Å; L65-V91 HydrophobicContact CG-CG1 4.48Å
66	R	65.8	Low	64.3	Low	133 Å²	133	69.9 Å²	69.9	50%	0.502	41%	0.409	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.9	-21.4	173.6	-78.6	169.4	174.7	-134.3	10.1	113.5	E62 Q64 I68 D88	E62-R66 WeakPolarHBondContact O-CB 3.17Å; E62-R66 WeakPolarHBondContact O-CG 3.3Å; E62-R66 PolarHBondContact O-N 2.84Å; Q64-R66 VanDerWaalsContact C-N 3.34Å; Q64-R66 PolarHBondContact O-N 3.48Å; R66-I68 PolarHBondContact O-N 3.13Å; R66-D88 IonicContact CZ-OD1 2.73Å; R66-D88 IonicContact NE-OD1 3.42Å; R66-D88 PolarHBondContact NE-OD1 3.37Å; R66-D88 IonicContact NH2-OD1 2.85Å; R66-D88 PolarHBondContact NH2-OD1 3.24Å; R66-D88 IonicContact NH2-OD2 3.54Å; R66-D88 PolarHBondContact NH2-OD2 3.38Å; R66-D88 VanDerWaalsContact NH2-OD2 3.08Å
67	K	69.6	Low	62	Low	149 Å²	149	75.7 Å²	75.7	65%	0.648	45%	0.446	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.2	-13.4	177.4	-61	175.7	-177.6	170.1	0	112.8	Q64 L65 P69	Q64-K67 WeakPolarHBondContact O-CB 3.26Å; Q64-K67 PolarHBondContact O-N 3.1Å; L65-K67 PolarHBondContact O-N 3.12Å; L65-K67 VanDerWaalsContact O-N 3.15Å; K67-P69 WeakPolarHBondContact O-CD 3.33Å
68	I	65.2	Low	60.1	Low	53 Å²	53	80.9 Å²	80.9	27%	0.272	47%	0.473	S	S	.	.	S	Bend	trans	-80.2	119.1	178.3	-55.8	176.7	0	0	0	108.3	L65 R66 G70 F71 F147	L65-I68 HydrophobicContact CD2-CD1 4.09Å; L65-I68 WeakPolarHBondContact O-CB 3.34Å; L65-I68 PolarHBondContact O-N 2.92Å; R66-I68 PolarHBondContact O-N 3.13Å; I68-G70 PolarHBondContact O-N 3.17Å; I68-F71 HydrophobicContact CB-CD2 4.19Å; I68-F71 HydrophobicContact CB-CE2 4.4Å; I68-F71 HydrophobicContact CG2-CD2 3.86Å; I68-F71 HydrophobicContact CG2-CE2 3.76Å; I68-F147 HydrophobicContact CD1-CD1 4.02Å; I68-F147 HydrophobicContact CD1-CE1 4.2Å
69	P	56.8	Low	58.2	Low	104 Å²	104	86 Å²	86	68%	0.675	50%	0.5	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.2	137.8	-179.6	23.9	-31.4	0	0	0	110.7	K67	K67-P69 WeakPolarHBondContact O-CD 3.33Å
70	G	57.8	Low	56.6	Low	28 Å²	28	85.7 Å²	85.7	29%	0.289	51%	0.513	S	S	.	.	T	Hydrogen-bonded Turn	trans	102	-14.5	177.3	0	0	0	0	0	116.9	I68	I68-G70 PolarHBondContact O-N 3.17Å
71	F	58.8	Low	55.4	Low	2 Å²	2	89.3 Å²	89.3	1%	0.009	52%	0.52	C	S	.	.	S	Bend	trans	-86.4	-28	-174.2	-84.8	-112.4	0	0	0	115.5	I68 V91 K94 S95 R98 F147	I68-F71 HydrophobicContact CB-CD2 4.19Å; I68-F71 HydrophobicContact CB-CE2 4.4Å; I68-F71 HydrophobicContact CG2-CD2 3.86Å; I68-F71 HydrophobicContact CG2-CE2 3.76Å; F71-V91 HydrophobicContact CB-CG2 4.3Å; F71-V91 HydrophobicContact CD1-CG1 4.11Å; F71-K94 HydrophobicContact CD1-CB 3.81Å; F71-K94 HydrophobicContact CD1-CD 4.35Å; F71-K94 HydrophobicContact CE1-CB 3.77Å; F71-K94 PolarHBondContact O-NZ 2.97Å; F71-S95 VanDerWaalsContact CE1-OG 3.3Å; F71-S95 WeakPolarHBondContact CE1-OG 3.36Å; F71-R98 VanDerWaalsContact CE1-NH1 3.3Å; F71-R98 VanDerWaalsContact CZ-CZ 3.42Å; F71-R98 VanDerWaalsContact CZ-NH1 3.26Å; F71-F147 HydrophobicContact CE2-CD1 4.09Å; F71-F147 AromaticContact CZ-CD1 3.72Å; F71-F147 HydrophobicContact CZ-CD1 3.72Å; F71-F147 AromaticContact CZ-CE1 3.81Å; F71-F147 HydrophobicContact CZ-CE1 3.81Å
72	C	58.1	Low	53.6	Low	48 Å²	48	94.6 Å²	94.6	32%	0.324	54%	0.544	S	S	.	.	S	Bend	trans	-131.8	8.7	176.4	-75.3	0	0	0	0	114	G74 C87 V91	C72-G74 PolarHBondContact O-N 3.41Å; C72-C87 WeakPolarHBondContact CB-SG 3.38Å; C72-C87 WeakPolarHBondContact SG-CB 3.14Å; C72-C87 CovalentContact SG-SG 2.05Å; C72-C87 PolarHBondContact SG-SG 3.29Å; C72-V91 WeakPolarHBondContact SG-CG2 3.23Å
73	Q	51	Low	52.2	Low	169 Å²	169	98.1 Å²	98.1	79%	0.79	56%	0.564	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.6	83.3	176.5	-84	178.4	-22.6	0	0	109.9
74	G	47.6	Very low	51	Low	47 Å²	47	102.1 Å²	102.1	49%	0.485	58%	0.577	S	S	.	*	T	Hydrogen-bonded Turn	trans	172.4	19.2	178.7	0	0	0	0	0	116.6	C72 T76	C72-G74 PolarHBondContact O-N 3.41Å; G74-T76 PolarHBondContact O-N 3.38Å; G74-T76 VanDerWaalsContact O-N 3.14Å
75	G	41.8	Very low	49.9	Very low	64 Å²	64	100 Å²	100	66%	0.66	57%	0.571	S	S	*	*			trans	-69.6	105.7	163.6	0	0	0	0	0	108.2	T77	G75-T77 PolarHBondContact O-N 2.86Å; G75-T77 VanDerWaalsContact O-N 3.17Å
76	T	38.6	Very low	49.2	Very low	111 Å²	111	104.1 Å²	104.1	68%	0.681	59%	0.588	S	S	*	*			trans	-60.6	117.1	167.9	38	0	0	0	0	108.2	G74 I78	G74-T76 PolarHBondContact O-N 3.38Å; G74-T76 VanDerWaalsContact O-N 3.14Å; T76-I78 PolarHBondContact O-N 3.26Å
77	T	38.3	Very low	48.9	Very low	149 Å²	149	98.9 Å²	98.9	91%	0.914	57%	0.571	S	S	*	*			trans	-67.2	84.4	164	19.5	0	0	0	0	108	G75	G75-T77 PolarHBondContact O-N 2.86Å; G75-T77 VanDerWaalsContact O-N 3.17Å
78	I	41	Very low	48.3	Very low	122 Å²	122	93.9 Å²	93.9	63%	0.626	55%	0.552	S	S	*	*			trans	-80.7	125.9	164.5	-51.4	-179.9	0	0	0	106.5	T76 G80	T76-I78 PolarHBondContact O-N 3.26Å; I78-G80 PolarHBondContact O-N 2.86Å; I78-G80 VanDerWaalsContact O-N 3.12Å
79	L	40.3	Very low	48.1	Very low	176 Å²	176	93.1 Å²	93.1	92%	0.921	55%	0.549	S	S	*	.	T	Hydrogen-bonded Turn	trans	-34.5	111.8	-179.5	-92.1	117.3	0	0	0	113.5
80	G	37.9	Very low	48.8	Very low	85 Å²	85	88.6 Å²	88.6	88%	0.876	52%	0.519	S	S	*	.	T	Hydrogen-bonded Turn	trans	89.4	1.6	158.4	0	0	0	0	0	118	I78	I78-G80 PolarHBondContact O-N 2.86Å; I78-G80 VanDerWaalsContact O-N 3.12Å
81	I	43.5	Very low	49.7	Very low	125 Å²	125	87.2 Å²	87.2	64%	0.641	51%	0.506	S	S	*	.			trans	-120.4	102.4	172.4	-53.6	178.6	0	0	0	108.3	N83	I81-N83 VanDerWaalsContact C-N 3.26Å; I81-N83 WeakPolarHBondContact CG2-OD1 3.33Å; I81-N83 PolarHBondContact O-N 2.88Å
82	E	36.3	Very low	50.7	Low	177 Å²	177	87.3 Å²	87.3	83%	0.827	51%	0.507	S	S	*	.			trans	-60.8	93.7	162.4	-84.9	-173.1	148.8	0	0	108.1	Q84	E82-Q84 PolarHBondContact O-N 3.41Å
83	N	40.3	Very low	51.9	Low	117 Å²	117	85.1 Å²	85.1	63%	0.626	49%	0.492	S	S	*	.			trans	-70.9	96.6	174.6	-93.1	-18.6	0	0	0	108.9	I81 V85	I81-N83 VanDerWaalsContact C-N 3.26Å; I81-N83 WeakPolarHBondContact CG2-OD1 3.33Å; I81-N83 PolarHBondContact O-N 2.88Å; N83-V85 HydrophobicContact CB-CG2 4.21Å; N83-V85 PolarHBondContact O-N 2.7Å
84	Q	41.5	Very low	53.6	Low	171 Å²	171	77.8 Å²	77.8	80%	0.799	46%	0.457	S	S	*	.			trans	-61.9	49	164.1	-69.3	-84.7	-15.7	0	0	111.6	E82 K86	E82-Q84 PolarHBondContact O-N 3.41Å; Q84-K86 PolarHBondContact O-N 3.27Å
85	V	48.9	Very low	55.5	Low	59 Å²	59	75.6 Å²	75.6	36%	0.358	43%	0.434	S	S	.	.			trans	-78.9	114.7	169.7	-178.6	0	0	0	0	106.3	N83 C87 I90 Q418	N83-V85 HydrophobicContact CB-CG2 4.21Å; N83-V85 PolarHBondContact O-N 2.7Å; V85-C87 VanDerWaalsContact C-N 3.28Å; V85-C87 PolarHBondContact O-N 3.5Å; V85-I90 HydrophobicContact CG1-CD1 3.45Å; V85-I90 VanDerWaalsContact CG1-CD1 3.45Å; V85-Q418 HydrophobicContact CG1-CB 4.34Å
86	K	53	Low	57.9	Low	97 Å²	97	72.5 Å²	72.5	42%	0.422	40%	0.403	S	S	.	.			trans	-60.8	85	-179.9	-70.4	178.4	175.6	-178.1	0	110.5	Q84 D88 V89 I90 G318 V320	Q84-K86 PolarHBondContact O-N 3.27Å; K86-D88 PolarHBondContact O-N 3Å; K86-V89 PolarHBondContact O-N 3.4Å; K86-I90 WeakPolarHBondContact O-CD1 3.23Å; K86-G318 PolarHBondContact NZ-O 3.18Å; K86-V320 HydrophobicContact CD-CG2 3.91Å
87	C	60.8	Low	60.4	Low	23 Å²	23	67.3 Å²	67.3	16%	0.155	37%	0.371	C	S	.	.	H	α-helix	trans	-55.3	-28	178.7	-146.8	0	0	0	0	111.1	C72 V85 I90 V91	C72-C87 WeakPolarHBondContact CB-SG 3.38Å; C72-C87 WeakPolarHBondContact SG-CB 3.14Å; C72-C87 CovalentContact SG-SG 2.05Å; C72-C87 PolarHBondContact SG-SG 3.29Å; V85-C87 VanDerWaalsContact C-N 3.28Å; V85-C87 PolarHBondContact O-N 3.5Å; C87-I90 PolarHBondContact O-N 2.92Å; C87-V91 WeakPolarHBondContact O-CB 3.33Å; C87-V91 WeakPolarHBondContact O-CG2 3.47Å; C87-V91 PolarHBondContact O-N 3.5Å
88	D	57.3	Low	63	Low	44 Å²	44	60.2 Å²	60.2	24%	0.235	33%	0.327	C	S	.	.	H	α-helix	trans	-50.3	-58.2	178.6	-72.5	-27.9	0	0	0	114.9	E62 R66 K86 I90 V91 G92	E62-D88 HydrophobicContact CG-CB 4.14Å; E62-D88 VanDerWaalsContact OE2-CB 3.25Å; E62-D88 WeakPolarHBondContact OE2-CB 3.23Å; R66-D88 IonicContact CZ-OD1 2.73Å; R66-D88 IonicContact NE-OD1 3.42Å; R66-D88 PolarHBondContact NE-OD1 3.37Å; R66-D88 IonicContact NH2-OD1 2.85Å; R66-D88 PolarHBondContact NH2-OD1 3.24Å; R66-D88 IonicContact NH2-OD2 3.54Å; R66-D88 PolarHBondContact NH2-OD2 3.38Å; R66-D88 VanDerWaalsContact NH2-OD2 3.08Å; K86-D88 PolarHBondContact O-N 3Å; D88-I90 VanDerWaalsContact C-N 3.32Å; D88-I90 PolarHBondContact O-N 3.41Å; D88-V91 PolarHBondContact O-N 3.28Å; D88-G92 PolarHBondContact O-N 2.81Å
89	V	60.6	Low	65.6	Low	37 Å²	37	54.9 Å²	54.9	22%	0.224	30%	0.3	C	S	.	.	H	α-helix	trans	-69.3	-35.2	-179.3	-177.9	0	0	0	0	111.3	K86 G92 Y93 V320	K86-V89 PolarHBondContact O-N 3.4Å; V89-G92 PolarHBondContact O-N 3.22Å; V89-Y93 HydrophobicContact CG1-CD2 4.33Å; V89-Y93 HydrophobicContact CG1-CE1 4.35Å; V89-Y93 HydrophobicContact CG1-CE2 3.81Å; V89-Y93 PolarHBondContact O-N 3.29Å; V89-Y93 VanDerWaalsContact O-N 3.15Å; V89-V320 HydrophobicContact CG1-CG1 4.18Å; V89-V320 HydrophobicContact CG2-CB 4.23Å; V89-V320 HydrophobicContact CG2-CG2 4.43Å
90	I	70.3	Confident	68.2	Low	9 Å²	9	46.5 Å²	46.5	5%	0.046	26%	0.256	C	S	.	.	H	α-helix	trans	-67.7	-39.5	-178.2	-64.8	155.7	0	0	0	110.8	V85 K86 C87 D88 Y93 K94 Q418 M420	V85-I90 HydrophobicContact CG1-CD1 3.45Å; V85-I90 VanDerWaalsContact CG1-CD1 3.45Å; K86-I90 WeakPolarHBondContact O-CD1 3.23Å; C87-I90 PolarHBondContact O-N 2.92Å; D88-I90 VanDerWaalsContact C-N 3.32Å; D88-I90 PolarHBondContact O-N 3.41Å; I90-Y93 PolarHBondContact O-N 3.23Å; I90-K94 HydrophobicContact CG2-CD 4.02Å; I90-K94 HydrophobicContact CG2-CG 4.33Å; I90-K94 VanDerWaalsContact O-CB 3.31Å; I90-K94 WeakPolarHBondContact O-CB 3.35Å; I90-K94 VanDerWaalsContact O-CG 3.25Å; I90-K94 WeakPolarHBondContact O-CG 3.35Å; I90-K94 PolarHBondContact O-N 3.27Å; I90-Q418 HydrophobicContact CD1-CB 4.4Å; I90-Q418 WeakPolarHBondContact CD1-O 3.09Å; I90-Q418 WeakPolarHBondContact CG1-O 3.26Å; I90-M420 HydrophobicContact CG1-CG 4.42Å; I90-M420 HydrophobicContact CG2-CE 4.23Å
91	V	76.9	Confident	71	Confident	0 Å²	0	44.6 Å²	44.6	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-64.7	-42	177.1	170	0	0	0	0	111.2	L65 F71 C72 C87 D88 K94 S95	L65-V91 HydrophobicContact CB-CG1 3.46Å; L65-V91 VanDerWaalsContact CB-CG1 3.46Å; L65-V91 HydrophobicContact CD1-CG1 4.26Å; L65-V91 HydrophobicContact CG-CG1 4.48Å; F71-V91 HydrophobicContact CB-CG2 4.3Å; F71-V91 HydrophobicContact CD1-CG1 4.11Å; C72-V91 WeakPolarHBondContact SG-CG2 3.23Å; C87-V91 WeakPolarHBondContact O-CB 3.33Å; C87-V91 WeakPolarHBondContact O-CG2 3.47Å; C87-V91 PolarHBondContact O-N 3.5Å; D88-V91 PolarHBondContact O-N 3.28Å; V91-K94 PolarHBondContact O-N 2.98Å; V91-S95 WeakPolarHBondContact O-CB 3.46Å; V91-S95 PolarHBondContact O-N 3.5Å; V91-S95 PolarHBondContact O-OG 2.88Å
92	G	80.9	Confident	73.6	Confident	3 Å²	3	38.7 Å²	38.7	3%	0.031	19%	0.193	C	C	.	.	H	α-helix	trans	-58.8	-50.2	175.3	0	0	0	0	0	111.8	D88 V89 S95 V96	D88-G92 PolarHBondContact O-N 2.81Å; V89-G92 PolarHBondContact O-N 3.22Å; G92-S95 WeakPolarHBondContact O-CB 3.39Å; G92-S95 PolarHBondContact O-N 3.11Å; G92-V96 PolarHBondContact O-N 3.04Å; G92-V96 VanDerWaalsContact O-N 3.11Å
93	Y	84	Confident	76.5	Confident	2 Å²	2	30.2 Å²	30.2	1%	0.008	15%	0.154	C	C	.	.	H	α-helix	trans	-63.5	-47.6	177.8	-67.7	-10.1	0	0	0	112.4	I57 V89 I90 S95 V96 Y97 L407 T408 N409 Y411 M420	I57-Y93 HydrophobicContact CD1-CD1 3.82Å; I57-Y93 HydrophobicContact CD1-CE1 4.04Å; I57-Y93 HydrophobicContact CG1-CD1 4.16Å; I57-Y93 HydrophobicContact CG1-CE1 4.49Å; I57-Y93 HydrophobicContact CG2-CE1 4.22Å; V89-Y93 HydrophobicContact CG1-CD2 4.33Å; V89-Y93 HydrophobicContact CG1-CE1 4.35Å; V89-Y93 HydrophobicContact CG1-CE2 3.81Å; V89-Y93 PolarHBondContact O-N 3.29Å; V89-Y93 VanDerWaalsContact O-N 3.15Å; I90-Y93 PolarHBondContact O-N 3.23Å; Y93-S95 PolarHBondContact O-N 3.16Å; Y93-S95 VanDerWaalsContact O-N 3.13Å; Y93-V96 PolarHBondContact O-N 3.23Å; Y93-Y97 VanDerWaalsContact O-CD2 3.31Å; Y93-Y97 WeakPolarHBondContact O-CD2 3.36Å; Y93-Y97 PolarHBondContact O-N 2.86Å; Y93-L407 WeakPolarHBondContact CE1-O 3.2Å; Y93-T408 HydrophobicContact CD1-CG2 4.05Å; Y93-T408 HydrophobicContact CG-CG2 4.01Å; Y93-N409 PolarHBondContact OH-ND2 3.34Å; Y93-Y411 AromaticContact CE2-CD2 3.89Å; Y93-Y411 HydrophobicContact CE2-CD2 3.89Å; Y93-Y411 HydrophobicContact CE2-CE2 4.47Å; Y93-M420 HydrophobicContact CD2-CE 4.08Å; Y93-M420 HydrophobicContact CD2-CG 3.86Å; Y93-M420 HydrophobicContact CD2-SD 4Å; Y93-M420 HydrophobicContact CE2-CG 4.25Å
94	K	84.8	Confident	79.3	Confident	16 Å²	16	24.8 Å²	24.8	7%	0.07	13%	0.125	C	C	.	.	H	α-helix	trans	-54.5	-32.4	174.6	-79.5	-179.7	-177.9	-178	0	113.1	F71 I90 V91 R98 D151	F71-K94 HydrophobicContact CD1-CB 3.81Å; F71-K94 HydrophobicContact CD1-CD 4.35Å; F71-K94 HydrophobicContact CE1-CB 3.77Å; F71-K94 PolarHBondContact O-NZ 2.97Å; I90-K94 HydrophobicContact CG2-CD 4.02Å; I90-K94 HydrophobicContact CG2-CG 4.33Å; I90-K94 VanDerWaalsContact O-CB 3.31Å; I90-K94 WeakPolarHBondContact O-CB 3.35Å; I90-K94 VanDerWaalsContact O-CG 3.25Å; I90-K94 WeakPolarHBondContact O-CG 3.35Å; I90-K94 PolarHBondContact O-N 3.27Å; V91-K94 PolarHBondContact O-N 2.98Å; K94-R98 PolarHBondContact O-N 3.42Å; K94-R98 PolarHBondContact O-NH1 3.47Å; K94-R98 VanDerWaalsContact O-NH1 3.16Å; K94-D151 WeakPolarHBondContact CE-OD2 3.37Å; K94-D151 IonicContact NZ-OD2 2.56Å; K94-D151 PolarHBondContact NZ-OD2 2.93Å
95	S	88.3	Confident	81.9	Confident	0 Å²	0	18.6 Å²	18.6	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-72.6	-42	177.5	-57.2	0	0	0	0	111	F71 V91 G92 Y93 Y97 R98 M99	F71-S95 VanDerWaalsContact CE1-OG 3.3Å; F71-S95 WeakPolarHBondContact CE1-OG 3.36Å; V91-S95 WeakPolarHBondContact O-CB 3.46Å; V91-S95 PolarHBondContact O-N 3.5Å; V91-S95 PolarHBondContact O-OG 2.88Å; G92-S95 WeakPolarHBondContact O-CB 3.39Å; G92-S95 PolarHBondContact O-N 3.11Å; Y93-S95 PolarHBondContact O-N 3.16Å; Y93-S95 VanDerWaalsContact O-N 3.13Å; S95-Y97 PolarHBondContact O-N 3.46Å; S95-R98 PolarHBondContact O-N 3.46Å; S95-M99 PolarHBondContact O-N 3.44Å
96	V	91.5	Very high	84.3	Confident	0 Å²	0	15.8 Å²	15.8	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-63.8	-38.9	175.2	171	0	0	0	0	112.5	S53 M56 I57 G92 Y93 R98 M99 C100 L407 T408	S53-V96 VanDerWaalsContact O-CG2 3.28Å; S53-V96 WeakPolarHBondContact O-CG2 3.41Å; M56-V96 HydrophobicContact CB-CG2 4.37Å; I57-V96 HydrophobicContact CD1-CB 4.15Å; I57-V96 HydrophobicContact CD1-CG2 3.33Å; I57-V96 HydrophobicContact CG1-CG2 3.54Å; G92-V96 PolarHBondContact O-N 3.04Å; G92-V96 VanDerWaalsContact O-N 3.11Å; Y93-V96 PolarHBondContact O-N 3.23Å; V96-R98 VanDerWaalsContact C-N 3.29Å; V96-R98 PolarHBondContact O-N 2.87Å; V96-M99 PolarHBondContact O-N 3.36Å; V96-C100 VanDerWaalsContact O-CB 3.29Å; V96-C100 WeakPolarHBondContact O-CB 3.45Å; V96-C100 PolarHBondContact O-N 2.79Å; V96-C100 PolarHBondContact O-SG 3.29Å; V96-L407 HydrophobicContact CG1-CB 4.03Å; V96-L407 HydrophobicContact CG1-CD1 4.19Å; V96-T408 HydrophobicContact CB-CG2 4.31Å; V96-T408 HydrophobicContact CG1-CG2 4.08Å
97	Y	91.9	Very high	86.4	Confident	1 Å²	1	11.2 Å²	11.2	0%	0.004	6%	0.063	C	C	.	.	H	α-helix	trans	-54.4	-45.4	173.3	-91.7	-103.6	0	0	0	112	Y93 S95 F101 N155 W158 F159 M404 T408	Y93-Y97 VanDerWaalsContact O-CD2 3.31Å; Y93-Y97 WeakPolarHBondContact O-CD2 3.36Å; Y93-Y97 PolarHBondContact O-N 2.86Å; S95-Y97 PolarHBondContact O-N 3.46Å; Y97-F101 WeakPolarHBondContact O-CB 3.24Å; Y97-F101 PolarHBondContact O-N 3.14Å; Y97-N155 WeakPolarHBondContact CE1-O 3.45Å; Y97-W158 HydrophobicContact CD1-CB 4.08Å; Y97-W158 AromaticContact CD1-CD1 3.64Å; Y97-W158 HydrophobicContact CD1-CG 4.26Å; Y97-W158 HydrophobicContact CE1-CB 4.35Å; Y97-F159 HydrophobicContact CE1-CB 4.15Å; Y97-F159 WeakPolarHBondContact OH-CD2 3.26Å; Y97-M404 HydrophobicContact CD1-CE 4.49Å; Y97-M404 HydrophobicContact CD1-SD 3.79Å; Y97-M404 HydrophobicContact CD2-CG 4.45Å; Y97-M404 HydrophobicContact CE1-CE 4.18Å; Y97-M404 HydrophobicContact CE1-SD 4.03Å; Y97-M404 HydrophobicContact CG-CG 4.39Å; Y97-M404 HydrophobicContact CG-SD 4.1Å; Y97-T408 HydrophobicContact CD2-CG2 3.88Å; Y97-T408 HydrophobicContact CE2-CG2 3.64Å
98	R	92.9	Very high	88.2	Confident	1 Å²	1	15.9 Å²	15.9	0%	0.004	8%	0.081	C	C	.	.	H	α-helix	trans	-73.1	-41.5	-179.5	-70.5	163	168.3	99.1	-4.3	112.8	F71 K94 S95 V96 F101 A102 A146 F147 I149 D151 F154	F71-R98 VanDerWaalsContact CE1-NH1 3.3Å; F71-R98 VanDerWaalsContact CZ-CZ 3.42Å; F71-R98 VanDerWaalsContact CZ-NH1 3.26Å; K94-R98 PolarHBondContact O-N 3.42Å; K94-R98 PolarHBondContact O-NH1 3.47Å; K94-R98 VanDerWaalsContact O-NH1 3.16Å; S95-R98 PolarHBondContact O-N 3.46Å; V96-R98 VanDerWaalsContact C-N 3.29Å; V96-R98 PolarHBondContact O-N 2.87Å; R98-F101 WeakPolarHBondContact O-CB 3.37Å; R98-F101 PolarHBondContact O-N 2.86Å; R98-A102 PolarHBondContact O-N 3.32Å; R98-A146 HydrophobicContact CB-CB 4.31Å; R98-A146 WeakPolarHBondContact CG-O 3.45Å; R98-F147 HydrophobicContact CB-CE2 4.39Å; R98-F147 HydrophobicContact CB-CZ 4.45Å; R98-I149 PolarHBondContact NE-O 2.87Å; R98-I149 PolarHBondContact NH2-O 2.85Å; R98-D151 IonicContact CZ-OD1 3.51Å; R98-D151 IonicContact NH1-OD1 2.86Å; R98-D151 PolarHBondContact NH1-OD1 3.39Å; R98-D151 IonicContact NH2-OD1 3.84Å; R98-D151 PolarHBondContact NH2-OD1 3.2Å; R98-F154 HydrophobicContact CG-CE1 4.21Å
99	M	94.8	Very high	90	Very high	10 Å²	10	17.5 Å²	17.5	5%	0.049	9%	0.089	C	C	.	.	H	α-helix	trans	-62.2	-45	176	-176.3	58	-167	0	0	111.2	V52 S53 M56 S95 V96 A102 M103 T143	V52-M99 HydrophobicContact CB-CE 4.2Å; V52-M99 HydrophobicContact CG1-CE 4.21Å; V52-M99 HydrophobicContact CG1-CG 4.4Å; V52-M99 HydrophobicContact CG1-SD 4.2Å; S53-M99 VanDerWaalsContact OG-CG 3.24Å; S53-M99 WeakPolarHBondContact OG-CG 3.35Å; M56-M99 HydrophobicContact SD-CB 4.11Å; S95-M99 PolarHBondContact O-N 3.44Å; V96-M99 PolarHBondContact O-N 3.36Å; M99-A102 PolarHBondContact O-N 2.89Å; M99-M103 HydrophobicContact CE-CG 4.33Å; M99-M103 HydrophobicContact CE-SD 4.48Å; M99-M103 HydrophobicContact CG-CE 4.44Å; M99-M103 PolarHBondContact O-N 2.74Å; M99-M103 VanDerWaalsContact O-N 3.08Å; M99-T143 HydrophobicContact SD-CG2 3.58Å; M99-T143 VanDerWaalsContact SD-CG2 3.58Å
100	C	96.4	Very high	91.7	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-72.2	-32.4	177.8	-62	0	0	0	0	112.7	V96 A102 M103 A104 M404	V96-C100 VanDerWaalsContact O-CB 3.29Å; V96-C100 WeakPolarHBondContact O-CB 3.45Å; V96-C100 PolarHBondContact O-N 2.79Å; V96-C100 PolarHBondContact O-SG 3.29Å; C100-A102 VanDerWaalsContact C-N 3.34Å; C100-M103 HydrophobicContact CB-CE 4.1Å; C100-M103 PolarHBondContact O-N 2.71Å; C100-M103 VanDerWaalsContact SG-CE 3.56Å; C100-A104 WeakPolarHBondContact O-CB 3.37Å; C100-A104 PolarHBondContact O-N 2.99Å; C100-M404 HydrophobicContact CB-CB 3.55Å; C100-M404 HydrophobicContact CB-CG 3.89Å; C100-M404 HydrophobicContact CB-SD 4.17Å
101	F	96.8	Very high	92.9	Very high	45 Å²	45	16.1 Å²	16.1	20%	0.197	8%	0.081	C	C	.	.	H	α-helix	trans	-57.6	-47	168.4	172.9	-95.4	0	0	0	111.3	Y97 R98 M103 A104 C105 A146 I149 F154 W158	Y97-F101 WeakPolarHBondContact O-CB 3.24Å; Y97-F101 PolarHBondContact O-N 3.14Å; R98-F101 WeakPolarHBondContact O-CB 3.37Å; R98-F101 PolarHBondContact O-N 2.86Å; F101-M103 PolarHBondContact O-N 3.26Å; F101-A104 PolarHBondContact O-N 3.18Å; F101-C105 VanDerWaalsContact CZ-SG 3.51Å; F101-C105 PolarHBondContact O-N 3.44Å; F101-C105 PolarHBondContact O-SG 3.37Å; F101-C105 VanDerWaalsContact O-SG 3.4Å; F101-A146 HydrophobicContact CD1-CB 3.81Å; F101-A146 HydrophobicContact CE1-CB 4.4Å; F101-I149 HydrophobicContact CD1-CD1 4.02Å; F101-I149 HydrophobicContact CE1-CD1 3.71Å; F101-I149 HydrophobicContact CZ-CD1 4.26Å; F101-F154 HydrophobicContact CB-CZ 4Å; F101-F154 HydrophobicContact CD1-CZ 4.41Å; F101-F154 AromaticContact CD2-CE2 3.82Å; F101-F154 HydrophobicContact CD2-CE2 3.82Å; F101-F154 AromaticContact CD2-CZ 3.88Å; F101-F154 HydrophobicContact CD2-CZ 3.88Å; F101-F154 HydrophobicContact CE2-CE2 4.03Å; F101-F154 HydrophobicContact CG-CE2 4.18Å; F101-F154 AromaticContact CG-CZ 3.84Å; F101-F154 HydrophobicContact CG-CZ 3.84Å; F101-W158 HydrophobicContact CB-CZ2 4Å; F101-W158 AromaticContact CD2-CD2 3.82Å; F101-W158 HydrophobicContact CD2-CD2 3.82Å; F101-W158 AromaticContact CD2-CE2 3.59Å; F101-W158 AromaticContact CD2-CE3 3.84Å; F101-W158 HydrophobicContact CD2-CE3 3.84Å; F101-W158 AromaticContact CD2-CH2 3.49Å; F101-W158 HydrophobicContact CD2-CH2 3.49Å; F101-W158 VanDerWaalsContact CD2-CH2 3.49Å; F101-W158 AromaticContact CD2-CZ2 3.46Å; F101-W158 HydrophobicContact CD2-CZ2 3.46Å; F101-W158 VanDerWaalsContact CD2-CZ2 3.46Å; F101-W158 AromaticContact CD2-CZ3 3.67Å; F101-W158 HydrophobicContact CD2-CZ3 3.67Å; F101-W158 HydrophobicContact CE2-CE3 4.25Å; F101-W158 AromaticContact CE2-CH2 3.95Å; F101-W158 HydrophobicContact CE2-CH2 3.95Å; F101-W158 HydrophobicContact CE2-CZ2 4.37Å; F101-W158 AromaticContact CE2-CZ3 3.88Å; F101-W158 HydrophobicContact CE2-CZ3 3.88Å; F101-W158 HydrophobicContact CG-CZ2 4.16Å
102	A	97.4	Very high	93.8	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-62.4	-43	178.4	0	0	0	0	0	112.7	R98 M99 C100 C105 F106 I142 A146	R98-A102 PolarHBondContact O-N 3.32Å; M99-A102 PolarHBondContact O-N 2.89Å; C100-A102 VanDerWaalsContact C-N 3.34Å; A102-C105 PolarHBondContact O-N 3.46Å; A102-F106 WeakPolarHBondContact O-CB 3.44Å; A102-F106 PolarHBondContact O-N 3Å; A102-I142 HydrophobicContact CB-CB 4.49Å; A102-I142 HydrophobicContact CB-CG2 3.82Å; A102-A146 HydrophobicContact CB-CB 4.13Å
103	M	97.4	Very high	94.4	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-61.4	-46	173.5	-70.5	-171.1	-71	0	0	111.9	L46 G49 M99 C100 F101 C105 F106 F107 L139	L46-M103 HydrophobicContact CD1-SD 4.24Å; G49-M103 VanDerWaalsContact CA-SD 3.52Å; M99-M103 HydrophobicContact CE-CG 4.33Å; M99-M103 HydrophobicContact CE-SD 4.48Å; M99-M103 HydrophobicContact CG-CE 4.44Å; M99-M103 PolarHBondContact O-N 2.74Å; M99-M103 VanDerWaalsContact O-N 3.08Å; C100-M103 HydrophobicContact CB-CE 4.1Å; C100-M103 PolarHBondContact O-N 2.71Å; C100-M103 VanDerWaalsContact SG-CE 3.56Å; F101-M103 PolarHBondContact O-N 3.26Å; M103-C105 PolarHBondContact O-N 2.98Å; M103-F106 WeakPolarHBondContact O-CB 3.47Å; M103-F106 PolarHBondContact O-N 2.93Å; M103-F107 HydrophobicContact CB-CD2 4.44Å; M103-F107 HydrophobicContact CB-CE2 4.38Å; M103-F107 WeakPolarHBondContact O-CD2 3.43Å; M103-F107 PolarHBondContact O-N 3.37Å; M103-L139 HydrophobicContact CG-CD1 4.44Å
104	A	97.9	Very high	94.8	Very high	3 Å²	3	21.3 Å²	21.3	3%	0.025	11%	0.114	C	C	.	.	H	α-helix	trans	-59.7	-46.8	178.3	0	0	0	0	0	111.1	C100 F101 F106 F107 F108 W158 C397 S400 L401	C100-A104 WeakPolarHBondContact O-CB 3.37Å; C100-A104 PolarHBondContact O-N 2.99Å; F101-A104 PolarHBondContact O-N 3.18Å; A104-F106 PolarHBondContact O-N 3.26Å; A104-F107 PolarHBondContact O-N 3.24Å; A104-F108 WeakPolarHBondContact O-CB 3.25Å; A104-F108 PolarHBondContact O-N 3.36Å; A104-W158 HydrophobicContact CB-CH2 4.32Å; A104-W158 HydrophobicContact CB-CZ2 3.91Å; A104-C397 PolarHBondContact O-SG 3.19Å; A104-S400 VanDerWaalsContact CA-OG 3.28Å; A104-S400 WeakPolarHBondContact CA-OG 3.31Å; A104-S400 WeakPolarHBondContact CB-OG 3.41Å; A104-S400 PolarHBondContact N-OG 3.49Å; A104-L401 HydrophobicContact CB-CD2 4.18Å; A104-L401 HydrophobicContact CB-CG 4.46Å
105	C	97.9	Very high	95.1	Very high	41 Å²	41	24.8 Å²	24.8	28%	0.277	13%	0.132	S	C	.	.	H	α-helix	trans	-61	-42.8	175.4	-72.2	0	0	0	0	112.4	F101 A102 M103 L109 I142	F101-C105 VanDerWaalsContact CZ-SG 3.51Å; F101-C105 PolarHBondContact O-N 3.44Å; F101-C105 PolarHBondContact O-SG 3.37Å; F101-C105 VanDerWaalsContact O-SG 3.4Å; A102-C105 PolarHBondContact O-N 3.46Å; M103-C105 PolarHBondContact O-N 2.98Å; C105-L109 VanDerWaalsContact O-CB 3.26Å; C105-L109 WeakPolarHBondContact O-CB 3.3Å; C105-L109 PolarHBondContact O-N 2.75Å; C105-I142 HydrophobicContact CB-CG2 4.08Å
106	F	98.1	Very high	95	Very high	0 Å²	0	34.9 Å²	34.9	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-59.9	-53.7	177.3	173	-97	0	0	0	111.5	F42 F45 A102 M103 A104 F108 L109 F110 K135 I138 L139 I142	F42-F106 HydrophobicContact CD1-CE1 4.27Å; F42-F106 HydrophobicContact CE1-CE1 4.25Å; F42-F106 HydrophobicContact CE1-CZ 4.18Å; F45-F106 HydrophobicContact CD2-CE1 4.01Å; F45-F106 AromaticContact CD2-CZ 3.88Å; F45-F106 HydrophobicContact CD2-CZ 3.88Å; F45-F106 HydrophobicContact CE2-CZ 4.21Å; A102-F106 WeakPolarHBondContact O-CB 3.44Å; A102-F106 PolarHBondContact O-N 3Å; M103-F106 WeakPolarHBondContact O-CB 3.47Å; M103-F106 PolarHBondContact O-N 2.93Å; A104-F106 PolarHBondContact O-N 3.26Å; F106-F108 PolarHBondContact O-N 3.33Å; F106-L109 PolarHBondContact O-N 3.11Å; F106-F110 HydrophobicContact CD2-CD2 4.19Å; F106-F110 HydrophobicContact CD2-CE2 4.02Å; F106-F110 HydrophobicContact CE1-CD2 4.21Å; F106-F110 HydrophobicContact CE1-CE2 4.45Å; F106-F110 AromaticContact CE2-CD2 3.85Å; F106-F110 HydrophobicContact CE2-CD2 3.85Å; F106-F110 AromaticContact CE2-CE2 3.41Å; F106-F110 HydrophobicContact CE2-CE2 3.41Å; F106-F110 VanDerWaalsContact CE2-CE2 3.41Å; F106-F110 HydrophobicContact CE2-CZ 4.45Å; F106-F110 AromaticContact CZ-CD2 3.86Å; F106-F110 HydrophobicContact CZ-CD2 3.86Å; F106-F110 AromaticContact CZ-CE2 3.66Å; F106-F110 HydrophobicContact CZ-CE2 3.66Å; F106-F110 WeakPolarHBondContact O-CD2 3.46Å; F106-F110 PolarHBondContact O-N 3.33Å; F106-F110 VanDerWaalsContact O-N 3.13Å; F106-K135 HydrophobicContact CE2-CB 4.37Å; F106-K135 WeakPolarHBondContact CE2-O 3.34Å; F106-K135 HydrophobicContact CZ-CB 4.3Å; F106-I138 HydrophobicContact CD2-CG2 4.23Å; F106-L139 HydrophobicContact CB-CD1 3.8Å; F106-L139 HydrophobicContact CD1-CD1 4.3Å; F106-L139 HydrophobicContact CD2-CB 3.92Å; F106-L139 HydrophobicContact CD2-CD1 4.27Å; F106-L139 HydrophobicContact CE2-CB 4.09Å; F106-L139 HydrophobicContact CG-CB 4.36Å; F106-L139 HydrophobicContact CG-CD1 3.87Å; F106-I142 HydrophobicContact CB-CD1 4.24Å
107	F	97.8	Very high	94.8	Very high	1 Å²	1	35.1 Å²	35.1	0%	0.004	17%	0.172	C	C	.	.	H	α-helix	trans	-68.7	-35.2	-179.8	-70.2	-60.7	0	0	0	112.5	F42 F45 L46 M103 A104 F110 S111 L396 C397	F42-F107 HydrophobicContact CB-CE1 4.48Å; F42-F107 HydrophobicContact CD1-CE1 4.16Å; F45-F107 HydrophobicContact CB-CZ 4.36Å; L46-F107 HydrophobicContact CB-CE2 3.92Å; L46-F107 HydrophobicContact CB-CZ 3.79Å; L46-F107 HydrophobicContact CD1-CE2 3.82Å; L46-F107 HydrophobicContact CG-CE2 4.44Å; M103-F107 HydrophobicContact CB-CD2 4.44Å; M103-F107 HydrophobicContact CB-CE2 4.38Å; M103-F107 WeakPolarHBondContact O-CD2 3.43Å; M103-F107 PolarHBondContact O-N 3.37Å; A104-F107 PolarHBondContact O-N 3.24Å; F107-F110 PolarHBondContact O-N 2.98Å; F107-S111 WeakPolarHBondContact O-CB 3.34Å; F107-S111 PolarHBondContact O-N 3.01Å; F107-L396 HydrophobicContact CB-CB 4.3Å; F107-L396 HydrophobicContact CD1-CB 3.62Å; F107-L396 HydrophobicContact CD1-CD1 3.81Å; F107-L396 HydrophobicContact CD1-CG 4.4Å; F107-L396 HydrophobicContact CD2-CB 4.04Å; F107-L396 HydrophobicContact CE1-CB 3.89Å; F107-L396 HydrophobicContact CE1-CD1 3.49Å; F107-L396 VanDerWaalsContact CE1-CD1 3.49Å; F107-L396 HydrophobicContact CE1-CG 4.34Å; F107-L396 HydrophobicContact CE2-CB 4.29Å; F107-L396 HydrophobicContact CG-CB 3.72Å; F107-L396 HydrophobicContact CZ-CB 4.22Å; F107-L396 HydrophobicContact CZ-CD1 4.17Å; F107-C397 HydrophobicContact CB-CB 3.82Å
108	F	97.6	Very high	94.3	Very high	121 Å²	121	43.2 Å²	43.2	53%	0.531	20%	0.203	S	C	.	.	H	α-helix	trans	-63.8	-42	174.1	-175.8	-101.3	0	0	0	112.1	A104 F106 F110 S111 A112	A104-F108 WeakPolarHBondContact O-CB 3.25Å; A104-F108 PolarHBondContact O-N 3.36Å; F106-F108 PolarHBondContact O-N 3.33Å; F108-F110 PolarHBondContact O-N 3.47Å; F108-S111 WeakPolarHBondContact O-CB 3.39Å; F108-S111 PolarHBondContact O-N 2.73Å; F108-A112 PolarHBondContact O-N 3.26Å
109	L	96.6	Very high	93.9	Very high	78 Å²	78	45.2 Å²	45.2	41%	0.408	21%	0.213	S	C	.	.	H	α-helix	trans	-59.1	-47.1	174.9	177.6	66.6	0	0	0	111.1	C105 F106 S111 A112 I113	C105-L109 VanDerWaalsContact O-CB 3.26Å; C105-L109 WeakPolarHBondContact O-CB 3.3Å; C105-L109 PolarHBondContact O-N 2.75Å; F106-L109 PolarHBondContact O-N 3.11Å; L109-S111 VanDerWaalsContact C-N 3.35Å; L109-A112 PolarHBondContact O-N 3.26Å; L109-I113 HydrophobicContact CD1-CD1 4.05Å; L109-I113 HydrophobicContact CD1-CG1 4.49Å; L109-I113 HydrophobicContact CG-CD1 3.92Å; L109-I113 VanDerWaalsContact O-CG1 3.31Å; L109-I113 WeakPolarHBondContact O-CG1 3.24Å; L109-I113 PolarHBondContact O-N 3.27Å
110	F	95.3	Very high	93.2	Very high	6 Å²	6	45.7 Å²	45.7	3%	0.026	22%	0.218	C	C	.	.	H	α-helix	trans	-65.5	-37.4	176.1	-87.7	-82.6	0	0	0	112.5	F42 F106 F107 F108 A112 I113 M114 I127 K135 H393	F42-F110 HydrophobicContact CE1-CD1 4.35Å; F42-F110 HydrophobicContact CE1-CG 4.39Å; F42-F110 HydrophobicContact CZ-CD1 4.13Å; F42-F110 HydrophobicContact CZ-CE1 4.28Å; F106-F110 HydrophobicContact CD2-CD2 4.19Å; F106-F110 HydrophobicContact CD2-CE2 4.02Å; F106-F110 HydrophobicContact CE1-CD2 4.21Å; F106-F110 HydrophobicContact CE1-CE2 4.45Å; F106-F110 AromaticContact CE2-CD2 3.85Å; F106-F110 HydrophobicContact CE2-CD2 3.85Å; F106-F110 AromaticContact CE2-CE2 3.41Å; F106-F110 HydrophobicContact CE2-CE2 3.41Å; F106-F110 VanDerWaalsContact CE2-CE2 3.41Å; F106-F110 HydrophobicContact CE2-CZ 4.45Å; F106-F110 AromaticContact CZ-CD2 3.86Å; F106-F110 HydrophobicContact CZ-CD2 3.86Å; F106-F110 AromaticContact CZ-CE2 3.66Å; F106-F110 HydrophobicContact CZ-CE2 3.66Å; F106-F110 WeakPolarHBondContact O-CD2 3.46Å; F106-F110 PolarHBondContact O-N 3.33Å; F106-F110 VanDerWaalsContact O-N 3.13Å; F107-F110 PolarHBondContact O-N 2.98Å; F108-F110 PolarHBondContact O-N 3.47Å; F110-A112 VanDerWaalsContact C-N 3.32Å; F110-A112 PolarHBondContact O-N 3.24Å; F110-I113 PolarHBondContact O-N 2.97Å; F110-M114 HydrophobicContact CD1-CE 4.16Å; F110-M114 HydrophobicContact CE1-CE 4.44Å; F110-M114 WeakPolarHBondContact O-CB 3.3Å; F110-M114 WeakPolarHBondContact O-CG 3.34Å; F110-M114 PolarHBondContact O-N 3.23Å; F110-I127 HydrophobicContact CE1-CG2 4.09Å; F110-K135 HydrophobicContact CE1-CD 4.4Å; F110-K135 HydrophobicContact CE1-CG 4.39Å; F110-K135 HydrophobicContact CE2-CG 4.43Å; F110-K135 HydrophobicContact CZ-CD 4.16Å; F110-K135 HydrophobicContact CZ-CG 3.73Å; F110-H393 HydrophobicContact CB-CB 4.32Å
111	S	94.9	Very high	92.5	Very high	10 Å²	10	52.2 Å²	52.2	7%	0.07	25%	0.246	C	C	.	.	H	α-helix	trans	-59.4	-43.3	173.5	-177	0	0	0	0	111.8	F107 F108 L109 M114 I115 S390	F107-S111 WeakPolarHBondContact O-CB 3.34Å; F107-S111 PolarHBondContact O-N 3.01Å; F108-S111 WeakPolarHBondContact O-CB 3.39Å; F108-S111 PolarHBondContact O-N 2.73Å; L109-S111 VanDerWaalsContact C-N 3.35Å; S111-M114 PolarHBondContact O-N 3.14Å; S111-I115 WeakPolarHBondContact O-CG1 3.01Å; S111-S390 WeakPolarHBondContact O-CB 3.41Å; S111-S390 PolarHBondContact O-OG 2.83Å; S111-S390 PolarHBondContact OG-O 3.47Å; S111-S390 PolarHBondContact OG-OG 3.45Å
112	A	95.8	Very high	92	Very high	46 Å²	46	52 Å²	52	38%	0.38	25%	0.247	S	C	.	.	H	α-helix	trans	-68.4	-42.2	178.8	0	0	0	0	0	113	F108 L109 F110 M114 I115	F108-A112 PolarHBondContact O-N 3.26Å; L109-A112 PolarHBondContact O-N 3.26Å; F110-A112 VanDerWaalsContact C-N 3.32Å; F110-A112 PolarHBondContact O-N 3.24Å; A112-M114 VanDerWaalsContact C-N 3.3Å; A112-M114 PolarHBondContact O-N 3.15Å; A112-I115 WeakPolarHBondContact O-CD1 3.48Å; A112-I115 WeakPolarHBondContact O-CG1 3.36Å; A112-I115 PolarHBondContact O-N 2.92Å
113	I	94.5	Very high	91.5	Very high	66 Å²	66	57 Å²	57	34%	0.338	28%	0.28	S	S	.	.	H	α-helix	trans	-64.5	-36.6	177.9	-68.4	166.7	0	0	0	111.2	L109 F110 I115	L109-I113 HydrophobicContact CD1-CD1 4.05Å; L109-I113 HydrophobicContact CD1-CG1 4.49Å; L109-I113 HydrophobicContact CG-CD1 3.92Å; L109-I113 VanDerWaalsContact O-CG1 3.31Å; L109-I113 WeakPolarHBondContact O-CG1 3.24Å; L109-I113 PolarHBondContact O-N 3.27Å; F110-I113 PolarHBondContact O-N 2.97Å; I113-I115 VanDerWaalsContact C-N 3.31Å; I113-I115 PolarHBondContact O-N 2.94Å
114	M	91.8	Very high	91.1	Very high	2 Å²	2	60.8 Å²	60.8	1%	0.01	29%	0.294	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89.2	13.6	-174.4	-59.5	-58.9	167	0	0	114.2	F110 S111 A112 R116 V117 R124 I127 Q128 Y389	F110-M114 HydrophobicContact CD1-CE 4.16Å; F110-M114 HydrophobicContact CE1-CE 4.44Å; F110-M114 WeakPolarHBondContact O-CB 3.3Å; F110-M114 WeakPolarHBondContact O-CG 3.34Å; F110-M114 PolarHBondContact O-N 3.23Å; S111-M114 PolarHBondContact O-N 3.14Å; A112-M114 VanDerWaalsContact C-N 3.3Å; A112-M114 PolarHBondContact O-N 3.15Å; M114-R116 PolarHBondContact O-N 2.64Å; M114-V117 HydrophobicContact CB-CG2 4.47Å; M114-V117 HydrophobicContact SD-CG2 4.21Å; M114-R124 WeakPolarHBondContact CE-O 3.5Å; M114-R124 HydrophobicContact SD-CB 4.22Å; M114-I127 HydrophobicContact CE-CB 4.2Å; M114-I127 HydrophobicContact CE-CG2 4.02Å; M114-Q128 HydrophobicContact CE-CB 3.73Å; M114-Q128 HydrophobicContact SD-CB 4.03Å; M114-Y389 HydrophobicContact SD-CD2 4.36Å
115	I	91.2	Very high	90.5	Very high	89 Å²	89	60.8 Å²	60.8	46%	0.456	29%	0.293	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.2	127.3	175.6	-68	172.5	0	0	0	110.1	S111 A112 I113 V117 R124	S111-I115 WeakPolarHBondContact O-CG1 3.01Å; A112-I115 WeakPolarHBondContact O-CD1 3.48Å; A112-I115 WeakPolarHBondContact O-CG1 3.36Å; A112-I115 PolarHBondContact O-N 2.92Å; I113-I115 VanDerWaalsContact C-N 3.31Å; I113-I115 PolarHBondContact O-N 2.94Å; I115-V117 PolarHBondContact O-N 3.46Å; I115-R124 PolarHBondContact O-NH1 3.25Å
116	R	86.8	Confident	89.9	Confident	212 Å²	212	62.4 Å²	62.4	80%	0.8	30%	0.302	S	S	*	.	T	Hydrogen-bonded Turn	trans	55.7	43	177.1	-62.6	176	178	166.5	-0.3	113.6	M114 R124	M114-R116 PolarHBondContact O-N 2.64Å; R116-R124 PolarHBondContact O-NH2 2.85Å
117	V	86.7	Confident	89.4	Confident	6 Å²	6	65.9 Å²	65.9	4%	0.036	32%	0.32	C	S	.	.			trans	-82.6	125.5	162.9	176.8	0	0	0	0	107.6	M114 I115 D122 R124 V385 Y389	M114-V117 HydrophobicContact CB-CG2 4.47Å; M114-V117 HydrophobicContact SD-CG2 4.21Å; I115-V117 PolarHBondContact O-N 3.46Å; V117-D122 HydrophobicContact CG1-CB 4.13Å; V117-R124 HydrophobicContact CG2-CB 4.01Å; V117-V385 HydrophobicContact CG1-CG1 4.38Å; V117-Y389 HydrophobicContact CB-CD2 3.9Å; V117-Y389 HydrophobicContact CB-CE2 4.35Å; V117-Y389 HydrophobicContact CG1-CD2 3.69Å; V117-Y389 HydrophobicContact CG1-CE2 3.62Å; V117-Y389 HydrophobicContact CG2-CD2 4.39Å
118	R	82.4	Confident	89	Confident	170 Å²	170	65.8 Å²	65.8	64%	0.642	32%	0.32	S	S	*	.			trans	-107.4	-26.3	-173.8	-71.6	-173.7	172.5	179.3	-2.9	114.2	N384 V385	R118-N384 CarbonylContact O-C 3.39Å; R118-N384 VanDerWaalsContact O-CA 3.25Å; R118-N384 WeakPolarHBondContact O-CA 3.29Å; R118-V385 PolarHBondContact O-N 2.67Å
119	N	83.5	Confident	88.3	Confident	43 Å²	43	60.5 Å²	60.5	23%	0.23	30%	0.297	C	S	.	.	S	Bend	trans	-152.5	169.9	-178.9	57.6	46.7	0	0	0	111.4	K121 D122 E383	N119-K121 PolarHBondContact O-N 2.93Å; N119-K121 WeakPolarHBondContact OD1-CB 3.41Å; N119-K121 PolarHBondContact OD1-N 3.23Å; N119-D122 PolarHBondContact O-N 3.47Å; N119-D122 PolarHBondContact OD1-N 2.85Å; N119-E383 WeakPolarHBondContact CB-O 3.41Å
120	S	81.4	Confident	87.6	Confident	20 Å²	20	56.8 Å²	56.8	14%	0.14	28%	0.278	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73	-9.5	-178.6	75.1	0	0	0	0	114	D122 A125 D379 E381 E382	S120-D122 VanDerWaalsContact C-N 3.34Å; S120-A125 WeakPolarHBondContact O-CB 3.2Å; S120-D379 WeakPolarHBondContact CB-OD2 3.38Å; S120-D379 PolarHBondContact OG-OD2 2.97Å; S120-E381 WeakPolarHBondContact CB-O 3.42Å; S120-E381 PolarHBondContact N-O 2.82Å; S120-E381 PolarHBondContact OG-O 3.02Å; S120-E382 WeakPolarHBondContact OG-CA 3.22Å
121	K	81.4	Confident	87.2	Confident	137 Å²	137	60 Å²	60	60%	0.596	29%	0.291	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.5	-18.9	177.1	-59.7	-179.9	-177.9	176.9	0	112.7	N119 E382	N119-K121 PolarHBondContact O-N 2.93Å; N119-K121 WeakPolarHBondContact OD1-CB 3.41Å; N119-K121 PolarHBondContact OD1-N 3.23Å; K121-E382 WeakPolarHBondContact CE-OE1 3.38Å; K121-E382 IonicContact NZ-OE1 2.69Å; K121-E382 PolarHBondContact NZ-OE1 3.01Å
122	D	85.9	Confident	86.8	Confident	42 Å²	42	59.7 Å²	59.7	23%	0.225	29%	0.289	C	S	.	.	S	Bend	trans	-59.6	133.6	172.9	-91.2	-17.7	0	0	0	110.3	V117 N119 S120 R124 A125	V117-D122 HydrophobicContact CG1-CB 4.13Å; N119-D122 PolarHBondContact O-N 3.47Å; N119-D122 PolarHBondContact OD1-N 2.85Å; S120-D122 VanDerWaalsContact C-N 3.34Å; D122-R124 PolarHBondContact O-N 3.02Å; D122-R124 IonicContact OD2-CZ 2.79Å; D122-R124 IonicContact OD2-NH2 2.71Å; D122-R124 PolarHBondContact OD2-NH2 3.29Å; D122-A125 VanDerWaalsContact O-CB 3.26Å; D122-A125 WeakPolarHBondContact O-CB 3.4Å; D122-A125 PolarHBondContact O-N 3.41Å
123	P	86.2	Confident	86.4	Confident	104 Å²	104	61.7 Å²	61.7	68%	0.675	29%	0.289	S	S	*	.	H	α-helix	trans	-55.7	-26.6	177.7	-26.5	33.6	0	0	0	113.6	A125 V126	P123-A125 VanDerWaalsContact C-N 3.32Å; P123-V126 WeakPolarHBondContact O-CB 3.22Å; P123-V126 PolarHBondContact O-N 3.09Å
124	R	89.8	Confident	86.2	Confident	80 Å²	80	63.6 Å²	63.6	30%	0.302	30%	0.295	S	S	.	.	H	α-helix	trans	-67.7	-29.4	176.1	-62.1	172.6	-68.6	169.3	6.1	112.4	M114 I115 R116 V117 D122 V126 I127 Q128	M114-R124 WeakPolarHBondContact CE-O 3.5Å; M114-R124 HydrophobicContact SD-CB 4.22Å; I115-R124 PolarHBondContact O-NH1 3.25Å; R116-R124 PolarHBondContact O-NH2 2.85Å; V117-R124 HydrophobicContact CG2-CB 4.01Å; D122-R124 PolarHBondContact O-N 3.02Å; D122-R124 IonicContact OD2-CZ 2.79Å; D122-R124 IonicContact OD2-NH2 2.71Å; D122-R124 PolarHBondContact OD2-NH2 3.29Å; R124-V126 VanDerWaalsContact C-N 3.26Å; R124-V126 PolarHBondContact O-N 3.34Å; R124-I127 WeakPolarHBondContact O-CB 3.33Å; R124-I127 PolarHBondContact O-N 3.39Å; R124-I127 VanDerWaalsContact O-N 3.12Å; R124-Q128 PolarHBondContact O-N 3.48Å
125	A	84.8	Confident	86.2	Confident	2 Å²	2	63.7 Å²	63.7	2%	0.017	30%	0.296	C	S	.	.	H	α-helix	trans	-66.7	-28.7	176.2	0	0	0	0	0	112.1	S120 D122 P123 I127 Q128 N129 Y389	S120-A125 WeakPolarHBondContact O-CB 3.2Å; D122-A125 VanDerWaalsContact O-CB 3.26Å; D122-A125 WeakPolarHBondContact O-CB 3.4Å; D122-A125 PolarHBondContact O-N 3.41Å; P123-A125 VanDerWaalsContact C-N 3.32Å; A125-I127 VanDerWaalsContact C-N 3.33Å; A125-Q128 WeakPolarHBondContact O-CB 3.32Å; A125-Q128 PolarHBondContact O-N 3.45Å; A125-N129 WeakPolarHBondContact O-CB 3.47Å; A125-N129 PolarHBondContact O-N 3.36Å; A125-N129 PolarHBondContact O-ND2 3.47Å; A125-Y389 HydrophobicContact CB-CE2 4.41Å
126	V	85.1	Confident	86.3	Confident	75 Å²	75	63.5 Å²	63.5	46%	0.455	29%	0.292	S	S	.	.	H	α-helix	trans	-64.4	-40.8	171.7	-172.2	0	0	0	0	110.6	P123 R124 G130 F131	P123-V126 WeakPolarHBondContact O-CB 3.22Å; P123-V126 PolarHBondContact O-N 3.09Å; R124-V126 VanDerWaalsContact C-N 3.26Å; R124-V126 PolarHBondContact O-N 3.34Å; V126-G130 WeakPolarHBondContact O-CA 3.25Å; V126-G130 PolarHBondContact O-N 3.16Å; V126-F131 HydrophobicContact CG1-CE2 3.97Å
127	I	88.2	Confident	86.6	Confident	73 Å²	73	58.2 Å²	58.2	37%	0.374	28%	0.279	S	S	.	.	H	α-helix	trans	-66.2	-39.5	173.5	-62.3	170.1	0	0	0	110.2	F110 M114 R124 A125 K135	F110-I127 HydrophobicContact CE1-CG2 4.09Å; M114-I127 HydrophobicContact CE-CB 4.2Å; M114-I127 HydrophobicContact CE-CG2 4.02Å; R124-I127 WeakPolarHBondContact O-CB 3.33Å; R124-I127 PolarHBondContact O-N 3.39Å; R124-I127 VanDerWaalsContact O-N 3.12Å; A125-I127 VanDerWaalsContact C-N 3.33Å; I127-K135 WeakPolarHBondContact O-CE 3.02Å; I127-K135 PolarHBondContact O-NZ 3.49Å
128	Q	88.3	Confident	87	Confident	0 Å²	0	61.4 Å²	61.4	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-62.6	-48	178.5	-178.8	67.1	-1.4	0	0	112	T38 M114 R124 A125 K135 Y387 Y389 H393	T38-Q128 HydrophobicContact CG2-CG 4.02Å; M114-Q128 HydrophobicContact CE-CB 3.73Å; M114-Q128 HydrophobicContact SD-CB 4.03Å; R124-Q128 PolarHBondContact O-N 3.48Å; A125-Q128 WeakPolarHBondContact O-CB 3.32Å; A125-Q128 PolarHBondContact O-N 3.45Å; Q128-K135 PolarHBondContact O-NZ 3.36Å; Q128-Y387 PolarHBondContact NE2-OH 3.31Å; Q128-Y389 HydrophobicContact CB-CD2 4.3Å; Q128-Y389 HydrophobicContact CB-CE2 4.18Å; Q128-Y389 HydrophobicContact CG-CD2 3.81Å; Q128-Y389 HydrophobicContact CG-CE2 3.79Å; Q128-Y389 HydrophobicContact CG-CG 4.23Å; Q128-H393 PolarHBondContact NE2-NE2 3.46Å; Q128-H393 PolarHBondContact OE1-NE2 2.91Å
129	N	84.3	Confident	87.6	Confident	9 Å²	9	53.7 Å²	53.7	5%	0.048	27%	0.266	C	S	.	.	H	α-helix	trans	-94.5	-7.3	-171.4	-63.8	-45.1	0	0	0	114.7	T38 A125 W132	T38-N129 WeakPolarHBondContact CB-OD1 3.34Å; T38-N129 WeakPolarHBondContact CG2-OD1 3.39Å; T38-N129 PolarHBondContact OG1-OD1 3.36Å; A125-N129 WeakPolarHBondContact O-CB 3.47Å; A125-N129 PolarHBondContact O-N 3.36Å; A125-N129 PolarHBondContact O-ND2 3.47Å; N129-W132 PolarHBondContact O-NE1 3.47Å
130	G	81.3	Confident	88.2	Confident	1 Å²	1	54.8 Å²	54.8	1%	0.01	27%	0.274	C	S	.	.	S	Bend	trans	-129.8	-165.4	-176.3	0	0	0	0	0	114.8	V126 W132 K135	V126-G130 WeakPolarHBondContact O-CA 3.25Å; V126-G130 PolarHBondContact O-N 3.16Å; G130-W132 VanDerWaalsContact C-N 3.32Å; G130-W132 PolarHBondContact O-N 3.38Å; G130-K135 WeakPolarHBondContact O-CE 3.16Å; G130-K135 PolarHBondContact O-NZ 3.2Å
131	F	86.4	Confident	88.9	Confident	72 Å²	72	55.9 Å²	55.9	32%	0.316	29%	0.289	S	S	.	.			trans	52.7	40	173.9	-60	-75.9	0	0	0	115.2	V126 F133 F134 K135	V126-F131 HydrophobicContact CG1-CE2 3.97Å; F131-F133 PolarHBondContact O-N 2.99Å; F131-F134 HydrophobicContact CB-CD2 4.24Å; F131-F134 AromaticContact CD1-CD2 3.88Å; F131-F134 HydrophobicContact CD1-CD2 3.88Å; F131-F134 HydrophobicContact CD1-CE2 4.18Å; F131-F134 PolarHBondContact O-N 2.77Å; F131-K135 WeakPolarHBondContact O-CG 3.38Å; F131-K135 PolarHBondContact O-N 3.3Å; F131-K135 VanDerWaalsContact O-N 3.1Å
132	W	87	Confident	89.6	Confident	5 Å²	5	51.5 Å²	51.5	2%	0.019	27%	0.271	C	S	.	.	H	α-helix	trans	-60	-40.6	-174.2	-61.7	111.1	0	0	0	113.9	L17 T38 V41 F42 F45 N129 G130 F134 K135 F136	L17-W132 HydrophobicContact CD2-CB 3.83Å; L17-W132 HydrophobicContact CD2-CG 4.49Å; T38-W132 HydrophobicContact CG2-CH2 4Å; T38-W132 HydrophobicContact CG2-CZ2 4.48Å; V41-W132 HydrophobicContact CB-CE3 4.2Å; V41-W132 HydrophobicContact CB-CH2 3.69Å; V41-W132 HydrophobicContact CB-CZ2 4.13Å; V41-W132 HydrophobicContact CB-CZ3 3.75Å; V41-W132 HydrophobicContact CG1-CD2 3.78Å; V41-W132 HydrophobicContact CG1-CE3 3.32Å; V41-W132 HydrophobicContact CG1-CH2 3.78Å; V41-W132 HydrophobicContact CG1-CZ2 4.21Å; V41-W132 HydrophobicContact CG1-CZ3 3.33Å; V41-W132 HydrophobicContact CG2-CH2 4.41Å; V41-W132 HydrophobicContact CG2-CZ2 4.37Å; F42-W132 HydrophobicContact CD2-CH2 4.03Å; F42-W132 HydrophobicContact CD2-CZ3 4.03Å; F42-W132 HydrophobicContact CE1-CZ3 4.39Å; F42-W132 AromaticContact CE2-CH2 3.86Å; F42-W132 HydrophobicContact CE2-CH2 3.86Å; F42-W132 AromaticContact CE2-CZ3 3.83Å; F42-W132 HydrophobicContact CE2-CZ3 3.83Å; F42-W132 HydrophobicContact CG-CZ3 4.39Å; F42-W132 HydrophobicContact CZ-CH2 4.47Å; F42-W132 HydrophobicContact CZ-CZ3 4.03Å; F45-W132 HydrophobicContact CE2-CE3 4.26Å; F45-W132 HydrophobicContact CZ-CE3 4.24Å; N129-W132 PolarHBondContact O-NE1 3.47Å; G130-W132 VanDerWaalsContact C-N 3.32Å; G130-W132 PolarHBondContact O-N 3.38Å; W132-F134 PolarHBondContact O-N 3.5Å; W132-K135 HydrophobicContact CE3-CD 3.77Å; W132-K135 HydrophobicContact CZ3-CD 4.04Å; W132-K135 WeakPolarHBondContact O-CB 3.49Å; W132-K135 PolarHBondContact O-N 3.07Å; W132-F136 PolarHBondContact O-N 3.06Å
133	F	87.2	Confident	90	Very high	88 Å²	88	50.5 Å²	50.5	39%	0.386	27%	0.267	S	S	.	.	H	α-helix	trans	-60.2	-45.6	176.7	176	-101.3	0	0	0	112.3	L17 C18 F131 K135 F136 L137	L17-F133 WeakPolarHBondContact O-CB 3.35Å; L17-F133 PolarHBondContact O-N 3.21Å; C18-F133 HydrophobicContact CB-CB 4.36Å; C18-F133 VanDerWaalsContact SG-CD2 3.59Å; C18-F133 VanDerWaalsContact SG-CG 3.52Å; F131-F133 PolarHBondContact O-N 2.99Å; F133-K135 PolarHBondContact O-N 3.41Å; F133-F136 WeakPolarHBondContact O-CB 3.43Å; F133-F136 PolarHBondContact O-N 2.84Å; F133-L137 PolarHBondContact O-N 2.88Å
134	F	90.4	Very high	90.4	Very high	106 Å²	106	49.3 Å²	49.3	47%	0.465	26%	0.258	S	S	.	.	H	α-helix	trans	-66.9	-38.1	178.6	-66.8	-75.5	0	0	0	111.7	F131 W132 F136 L137 I138	F131-F134 HydrophobicContact CB-CD2 4.24Å; F131-F134 AromaticContact CD1-CD2 3.88Å; F131-F134 HydrophobicContact CD1-CD2 3.88Å; F131-F134 HydrophobicContact CD1-CE2 4.18Å; F131-F134 PolarHBondContact O-N 2.77Å; W132-F134 PolarHBondContact O-N 3.5Å; F134-F136 VanDerWaalsContact C-N 3.33Å; F134-F136 PolarHBondContact O-N 3.38Å; F134-L137 PolarHBondContact O-N 3.3Å; F134-I138 VanDerWaalsContact O-CG1 3.28Å; F134-I138 WeakPolarHBondContact O-CG1 3.4Å; F134-I138 PolarHBondContact O-N 2.68Å
135	K	92.6	Very high	90.5	Very high	4 Å²	4	47.4 Å²	47.4	2%	0.017	26%	0.263	C	S	.	.	H	α-helix	trans	-59.8	-44.3	172.7	-67.4	173.1	176.9	158.5	0	111.8	F42 F45 F106 F110 I127 Q128 G130 F131 W132 F133 I138 L139	F42-K135 HydrophobicContact CE1-CD 4.16Å; F42-K135 HydrophobicContact CZ-CD 3.98Å; F45-K135 HydrophobicContact CE2-CB 3.89Å; F45-K135 HydrophobicContact CZ-CB 4.45Å; F106-K135 HydrophobicContact CE2-CB 4.37Å; F106-K135 WeakPolarHBondContact CE2-O 3.34Å; F106-K135 HydrophobicContact CZ-CB 4.3Å; F110-K135 HydrophobicContact CE1-CD 4.4Å; F110-K135 HydrophobicContact CE1-CG 4.39Å; F110-K135 HydrophobicContact CE2-CG 4.43Å; F110-K135 HydrophobicContact CZ-CD 4.16Å; F110-K135 HydrophobicContact CZ-CG 3.73Å; I127-K135 WeakPolarHBondContact O-CE 3.02Å; I127-K135 PolarHBondContact O-NZ 3.49Å; Q128-K135 PolarHBondContact O-NZ 3.36Å; G130-K135 WeakPolarHBondContact O-CE 3.16Å; G130-K135 PolarHBondContact O-NZ 3.2Å; F131-K135 WeakPolarHBondContact O-CG 3.38Å; F131-K135 PolarHBondContact O-N 3.3Å; F131-K135 VanDerWaalsContact O-N 3.1Å; W132-K135 HydrophobicContact CE3-CD 3.77Å; W132-K135 HydrophobicContact CZ3-CD 4.04Å; W132-K135 WeakPolarHBondContact O-CB 3.49Å; W132-K135 PolarHBondContact O-N 3.07Å; F133-K135 PolarHBondContact O-N 3.41Å; K135-I138 PolarHBondContact O-N 2.71Å; K135-L139 PolarHBondContact O-N 3.13Å
136	F	92	Very high	90.9	Very high	85 Å²	85	47.5 Å²	47.5	37%	0.373	26%	0.263	S	S	.	.	H	α-helix	trans	-61.5	-44.1	176	179.5	-100.6	0	0	0	111.5	F45 L48 W132 F133 F134 I138 L139 V140	F45-F136 HydrophobicContact CE1-CD2 4.45Å; F45-F136 HydrophobicContact CZ-CB 4.26Å; L48-F136 HydrophobicContact CD2-CE2 3.87Å; W132-F136 PolarHBondContact O-N 3.06Å; F133-F136 WeakPolarHBondContact O-CB 3.43Å; F133-F136 PolarHBondContact O-N 2.84Å; F134-F136 VanDerWaalsContact C-N 3.33Å; F134-F136 PolarHBondContact O-N 3.38Å; F136-I138 VanDerWaalsContact C-N 3.34Å; F136-I138 PolarHBondContact O-N 3.26Å; F136-L139 WeakPolarHBondContact O-CB 3.46Å; F136-L139 PolarHBondContact O-N 3.29Å; F136-V140 HydrophobicContact CD1-CG2 4.25Å; F136-V140 HydrophobicContact CE1-CG2 3.79Å; F136-V140 HydrophobicContact CE2-CG2 4.3Å; F136-V140 HydrophobicContact CZ-CG2 3.82Å; F136-V140 WeakPolarHBondContact O-CG2 3.26Å; F136-V140 PolarHBondContact O-N 3.42Å
137	L	93.9	Very high	91.1	Very high	101 Å²	101	45.5 Å²	45.5	53%	0.529	25%	0.249	S	C	.	.	H	α-helix	trans	-61.8	-40.6	175.9	-166.8	109.3	0	0	0	112.3	F133 F134 V140 G141	F133-L137 PolarHBondContact O-N 2.88Å; F134-L137 PolarHBondContact O-N 3.3Å; L137-V140 PolarHBondContact O-N 3.25Å; L137-G141 PolarHBondContact O-N 3.45Å
138	I	95.2	Very high	91.1	Very high	72 Å²	72	49.8 Å²	49.8	37%	0.369	27%	0.265	S	S	.	.	H	α-helix	trans	-60.1	-47.1	174.1	-69.6	165.1	0	0	0	110.1	F106 F134 K135 F136 V140 G141 I142	F106-I138 HydrophobicContact CD2-CG2 4.23Å; F134-I138 VanDerWaalsContact O-CG1 3.28Å; F134-I138 WeakPolarHBondContact O-CG1 3.4Å; F134-I138 PolarHBondContact O-N 2.68Å; K135-I138 PolarHBondContact O-N 2.71Å; F136-I138 VanDerWaalsContact C-N 3.34Å; F136-I138 PolarHBondContact O-N 3.26Å; I138-V140 PolarHBondContact O-N 2.95Å; I138-G141 PolarHBondContact O-N 3.24Å; I138-I142 HydrophobicContact CG2-CD1 3.74Å; I138-I142 HydrophobicContact CG2-CG1 4.33Å; I138-I142 VanDerWaalsContact O-CG1 3.3Å; I138-I142 WeakPolarHBondContact O-CG1 3.18Å; I138-I142 PolarHBondContact O-N 2.99Å
139	L	95.5	Very high	91	Very high	9 Å²	9	51.8 Å²	51.8	5%	0.047	28%	0.275	C	S	.	.	H	α-helix	trans	-59.6	-44.8	177.7	178.2	61.5	0	0	0	111.8	F45 M103 F106 K135 F136 T143	F45-L139 HydrophobicContact CB-CD2 4.43Å; M103-L139 HydrophobicContact CG-CD1 4.44Å; F106-L139 HydrophobicContact CB-CD1 3.8Å; F106-L139 HydrophobicContact CD1-CD1 4.3Å; F106-L139 HydrophobicContact CD2-CB 3.92Å; F106-L139 HydrophobicContact CD2-CD1 4.27Å; F106-L139 HydrophobicContact CE2-CB 4.09Å; F106-L139 HydrophobicContact CG-CB 4.36Å; F106-L139 HydrophobicContact CG-CD1 3.87Å; K135-L139 PolarHBondContact O-N 3.13Å; F136-L139 WeakPolarHBondContact O-CB 3.46Å; F136-L139 PolarHBondContact O-N 3.29Å; L139-T143 WeakPolarHBondContact O-CB 3.42Å; L139-T143 PolarHBondContact O-N 2.98Å; L139-T143 PolarHBondContact O-OG1 3.3Å
140	V	95.2	Very high	90.8	Very high	65 Å²	65	56.1 Å²	56.1	39%	0.394	30%	0.304	S	S	.	.	H	α-helix	trans	-62.4	-44.3	175.5	172.6	0	0	0	0	111	F136 L137 I138 T143 V144	F136-V140 HydrophobicContact CD1-CG2 4.25Å; F136-V140 HydrophobicContact CE1-CG2 3.79Å; F136-V140 HydrophobicContact CE2-CG2 4.3Å; F136-V140 HydrophobicContact CZ-CG2 3.82Å; F136-V140 WeakPolarHBondContact O-CG2 3.26Å; F136-V140 PolarHBondContact O-N 3.42Å; L137-V140 PolarHBondContact O-N 3.25Å; I138-V140 PolarHBondContact O-N 2.95Å; V140-T143 WeakPolarHBondContact O-CB 3.21Å; V140-T143 PolarHBondContact O-N 2.89Å; V140-V144 HydrophobicContact CG1-CG2 4.42Å; V140-V144 WeakPolarHBondContact O-CG2 3.36Å; V140-V144 PolarHBondContact O-N 3.33Å
141	G	96.3	Very high	90.4	Very high	44 Å²	44	58.6 Å²	58.6	45%	0.454	32%	0.317	S	S	.	.	H	α-helix	trans	-61	-46.5	178.5	0	0	0	0	0	113	L137 I138 T143 V144 G145	L137-G141 PolarHBondContact O-N 3.45Å; I138-G141 PolarHBondContact O-N 3.24Å; G141-T143 VanDerWaalsContact C-N 3.3Å; G141-T143 PolarHBondContact O-N 3.06Å; G141-V144 PolarHBondContact O-N 3.46Å; G141-G145 PolarHBondContact O-N 2.74Å
142	I	96.8	Very high	89.8	Confident	44 Å²	44	57.1 Å²	57.1	23%	0.226	32%	0.322	C	S	.	.	H	α-helix	trans	-62.4	-40.6	174.9	-62.5	168	0	0	0	110.1	A102 C105 F106 I138 G145 A146	A102-I142 HydrophobicContact CB-CB 4.49Å; A102-I142 HydrophobicContact CB-CG2 3.82Å; C105-I142 HydrophobicContact CB-CG2 4.08Å; F106-I142 HydrophobicContact CB-CD1 4.24Å; I138-I142 HydrophobicContact CG2-CD1 3.74Å; I138-I142 HydrophobicContact CG2-CG1 4.33Å; I138-I142 VanDerWaalsContact O-CG1 3.3Å; I138-I142 WeakPolarHBondContact O-CG1 3.18Å; I138-I142 PolarHBondContact O-N 2.99Å; I142-G145 PolarHBondContact O-N 2.92Å; I142-A146 WeakPolarHBondContact O-CB 3.39Å; I142-A146 PolarHBondContact O-N 3.47Å
143	T	94.6	Very high	89.5	Confident	21 Å²	21	60.2 Å²	60.2	13%	0.129	35%	0.349	C	S	.	.	H	α-helix	trans	-60.7	-52	177.7	-57.6	0	0	0	0	111	M99 L139 V140 G141 G145 A146 F147	M99-T143 HydrophobicContact SD-CG2 3.58Å; M99-T143 VanDerWaalsContact SD-CG2 3.58Å; L139-T143 WeakPolarHBondContact O-CB 3.42Å; L139-T143 PolarHBondContact O-N 2.98Å; L139-T143 PolarHBondContact O-OG1 3.3Å; V140-T143 WeakPolarHBondContact O-CB 3.21Å; V140-T143 PolarHBondContact O-N 2.89Å; G141-T143 VanDerWaalsContact C-N 3.3Å; G141-T143 PolarHBondContact O-N 3.06Å; T143-G145 VanDerWaalsContact C-N 3.28Å; T143-G145 PolarHBondContact O-N 3.48Å; T143-A146 WeakPolarHBondContact O-CB 3.43Å; T143-A146 PolarHBondContact O-N 3.01Å; T143-A146 VanDerWaalsContact O-N 3.08Å; T143-F147 HydrophobicContact CG2-CD2 4.13Å; T143-F147 HydrophobicContact CG2-CE2 3.95Å; T143-F147 VanDerWaalsContact O-CD2 3.32Å; T143-F147 WeakPolarHBondContact O-CD2 3.3Å; T143-F147 PolarHBondContact O-N 3.27Å
144	V	93.1	Very high	89.5	Confident	80 Å²	80	57.9 Å²	57.9	49%	0.485	34%	0.338	S	S	.	.	H	α-helix	trans	-55.6	-46.7	176.5	172.4	0	0	0	0	110.4	V140 G141 A146 F147 F148	V140-V144 HydrophobicContact CG1-CG2 4.42Å; V140-V144 WeakPolarHBondContact O-CG2 3.36Å; V140-V144 PolarHBondContact O-N 3.33Å; G141-V144 PolarHBondContact O-N 3.46Å; V144-A146 VanDerWaalsContact C-N 3.34Å; V144-A146 PolarHBondContact O-N 3.29Å; V144-F147 PolarHBondContact O-N 2.9Å; V144-F148 HydrophobicContact CG1-CD2 4.4Å; V144-F148 HydrophobicContact CG1-CE2 3.84Å; V144-F148 WeakPolarHBondContact O-CD2 3.21Å
145	G	93.3	Very high	89.2	Confident	40 Å²	40	53.4 Å²	53.4	41%	0.412	32%	0.32	S	S	.	.	H	α-helix	trans	-58.5	-40.8	175.8	0	0	0	0	0	113.8	G141 I142 T143 F147 F148	G141-G145 PolarHBondContact O-N 2.74Å; I142-G145 PolarHBondContact O-N 2.92Å; T143-G145 VanDerWaalsContact C-N 3.28Å; T143-G145 PolarHBondContact O-N 3.48Å; G145-F147 VanDerWaalsContact C-N 3.27Å; G145-F147 PolarHBondContact O-N 3.25Å; G145-F148 PolarHBondContact O-N 2.97Å; G145-F148 VanDerWaalsContact O-N 3.13Å
146	A	92.9	Very high	88.9	Confident	3 Å²	3	54.4 Å²	54.4	3%	0.025	33%	0.327	C	S	.	.	H	α-helix	trans	-63.7	-31.4	178.2	0	0	0	0	0	112.8	R98 F101 A102 I142 T143 V144 F148 I149	R98-A146 HydrophobicContact CB-CB 4.31Å; R98-A146 WeakPolarHBondContact CG-O 3.45Å; F101-A146 HydrophobicContact CD1-CB 3.81Å; F101-A146 HydrophobicContact CE1-CB 4.4Å; A102-A146 HydrophobicContact CB-CB 4.13Å; I142-A146 WeakPolarHBondContact O-CB 3.39Å; I142-A146 PolarHBondContact O-N 3.47Å; T143-A146 WeakPolarHBondContact O-CB 3.43Å; T143-A146 PolarHBondContact O-N 3.01Å; T143-A146 VanDerWaalsContact O-N 3.08Å; V144-A146 VanDerWaalsContact C-N 3.34Å; V144-A146 PolarHBondContact O-N 3.29Å; A146-F148 VanDerWaalsContact C-N 3.26Å; A146-F148 PolarHBondContact O-N 2.94Å; A146-I149 HydrophobicContact CB-CD1 4.38Å; A146-I149 WeakPolarHBondContact O-CB 3.3Å; A146-I149 WeakPolarHBondContact O-CG1 3.42Å; A146-I149 PolarHBondContact O-N 3.04Å
147	F	89	Confident	88.8	Confident	33 Å²	33	53.9 Å²	53.9	15%	0.145	33%	0.331	C	S	.	.	H	α-helix	trans	-70.3	-20.2	176	-85.4	-89.4	0	0	0	113.9	M56 I68 F71 R98 T143 V144 G145 I149	M56-F147 HydrophobicContact CE-CE2 4.01Å; M56-F147 HydrophobicContact CE-CZ 3.5Å; M56-F147 HydrophobicContact SD-CZ 4.02Å; I68-F147 HydrophobicContact CD1-CD1 4.02Å; I68-F147 HydrophobicContact CD1-CE1 4.2Å; F71-F147 HydrophobicContact CE2-CD1 4.09Å; F71-F147 AromaticContact CZ-CD1 3.72Å; F71-F147 HydrophobicContact CZ-CD1 3.72Å; F71-F147 AromaticContact CZ-CE1 3.81Å; F71-F147 HydrophobicContact CZ-CE1 3.81Å; R98-F147 HydrophobicContact CB-CE2 4.39Å; R98-F147 HydrophobicContact CB-CZ 4.45Å; T143-F147 HydrophobicContact CG2-CD2 4.13Å; T143-F147 HydrophobicContact CG2-CE2 3.95Å; T143-F147 VanDerWaalsContact O-CD2 3.32Å; T143-F147 WeakPolarHBondContact O-CD2 3.3Å; T143-F147 PolarHBondContact O-N 3.27Å; V144-F147 PolarHBondContact O-N 2.9Å; G145-F147 VanDerWaalsContact C-N 3.27Å; G145-F147 PolarHBondContact O-N 3.25Å; F147-I149 VanDerWaalsContact C-N 3.3Å
148	F	88.6	Confident	88.7	Confident	164 Å²	164	50.6 Å²	50.6	72%	0.719	31%	0.311	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.2	-3.5	173.6	-73.6	-82.2	0	0	0	113.9	V144 G145 A146 P150	V144-F148 HydrophobicContact CG1-CD2 4.4Å; V144-F148 HydrophobicContact CG1-CE2 3.84Å; V144-F148 WeakPolarHBondContact O-CD2 3.21Å; G145-F148 PolarHBondContact O-N 2.97Å; G145-F148 VanDerWaalsContact O-N 3.13Å; A146-F148 VanDerWaalsContact C-N 3.26Å; A146-F148 PolarHBondContact O-N 2.94Å; F148-P150 WeakPolarHBondContact O-CD 3.39Å
149	I	85.9	Confident	88.5	Confident	41 Å²	41	47.1 Å²	47.1	21%	0.21	29%	0.293	C	S	.	.	P	Polyproline II helix	trans	-69.6	119.4	177.3	-60.1	172.3	0	0	0	108.9	R98 F101 A146 F147 F154	R98-I149 PolarHBondContact NE-O 2.87Å; R98-I149 PolarHBondContact NH2-O 2.85Å; F101-I149 HydrophobicContact CD1-CD1 4.02Å; F101-I149 HydrophobicContact CE1-CD1 3.71Å; F101-I149 HydrophobicContact CZ-CD1 4.26Å; A146-I149 HydrophobicContact CB-CD1 4.38Å; A146-I149 WeakPolarHBondContact O-CB 3.3Å; A146-I149 WeakPolarHBondContact O-CG1 3.42Å; A146-I149 PolarHBondContact O-N 3.04Å; F147-I149 VanDerWaalsContact C-N 3.3Å; I149-F154 HydrophobicContact CD1-CE2 3.97Å; I149-F154 HydrophobicContact CD1-CZ 4.13Å; I149-F154 HydrophobicContact CG2-CB 4.15Å; I149-F154 HydrophobicContact CG2-CD1 4.16Å; I149-F154 HydrophobicContact CG2-CD2 3.88Å; I149-F154 HydrophobicContact CG2-CE2 4.33Å; I149-F154 HydrophobicContact CG2-CG 3.78Å
150	P	80.3	Confident	88.4	Confident	101 Å²	101	52.4 Å²	52.4	66%	0.656	31%	0.314	S	S	*	.	P	Polyproline II helix	trans	-68.4	153.3	-178.5	28.4	-34.5	0	0	0	111.8	F148	F148-P150 WeakPolarHBondContact O-CD 3.39Å
151	D	71.9	Confident	88.4	Confident	53 Å²	53	55.1 Å²	55.1	28%	0.283	32%	0.32	S	S	.	.	S	Bend	trans	-67	139.8	173.3	-80	-14.3	0	0	0	110.8	K94 R98	K94-D151 WeakPolarHBondContact CE-OD2 3.37Å; K94-D151 IonicContact NZ-OD2 2.56Å; K94-D151 PolarHBondContact NZ-OD2 2.93Å; R98-D151 IonicContact CZ-OD1 3.51Å; R98-D151 IonicContact NH1-OD1 2.86Å; R98-D151 PolarHBondContact NH1-OD1 3.39Å; R98-D151 IonicContact NH2-OD1 3.84Å; R98-D151 PolarHBondContact NH2-OD1 3.2Å
152	G	74.4	Confident	88.3	Confident	41 Å²	41	53 Å²	53	42%	0.423	30%	0.299	S	S	.	.	S	Bend	trans	166.3	-140.1	-176	0	0	0	0	0	110.6	F154	G152-F154 PolarHBondContact O-N 2.86Å; G152-F154 VanDerWaalsContact O-N 3.1Å
153	A	81.1	Confident	88.2	Confident	70 Å²	70	51.4 Å²	51.4	58%	0.579	29%	0.29	S	S	*	.	H	α-helix	trans	-62.4	-16.3	177.5	0	0	0	0	0	114	N155 S156 V157	A153-N155 PolarHBondContact O-N 3.3Å; A153-S156 PolarHBondContact O-N 3.46Å; A153-V157 HydrophobicContact CB-CG2 4.48Å; A153-V157 WeakPolarHBondContact O-CB 3.43Å; A153-V157 VanDerWaalsContact O-CG2 3.29Å; A153-V157 WeakPolarHBondContact O-CG2 3.49Å; A153-V157 PolarHBondContact O-N 2.61Å
154	F	86.8	Confident	88.3	Confident	38 Å²	38	54.9 Å²	54.9	17%	0.167	31%	0.311	C	S	.	.	H	α-helix	trans	-52.8	-53.2	-176.6	175.6	-102.5	0	0	0	112.8	R98 F101 I149 G152 S156 V157 W158	R98-F154 HydrophobicContact CG-CE1 4.21Å; F101-F154 HydrophobicContact CB-CZ 4Å; F101-F154 HydrophobicContact CD1-CZ 4.41Å; F101-F154 AromaticContact CD2-CE2 3.82Å; F101-F154 HydrophobicContact CD2-CE2 3.82Å; F101-F154 AromaticContact CD2-CZ 3.88Å; F101-F154 HydrophobicContact CD2-CZ 3.88Å; F101-F154 HydrophobicContact CE2-CE2 4.03Å; F101-F154 HydrophobicContact CG-CE2 4.18Å; F101-F154 AromaticContact CG-CZ 3.84Å; F101-F154 HydrophobicContact CG-CZ 3.84Å; I149-F154 HydrophobicContact CD1-CE2 3.97Å; I149-F154 HydrophobicContact CD1-CZ 4.13Å; I149-F154 HydrophobicContact CG2-CB 4.15Å; I149-F154 HydrophobicContact CG2-CD1 4.16Å; I149-F154 HydrophobicContact CG2-CD2 3.88Å; I149-F154 HydrophobicContact CG2-CE2 4.33Å; I149-F154 HydrophobicContact CG2-CG 3.78Å; G152-F154 PolarHBondContact O-N 2.86Å; G152-F154 VanDerWaalsContact O-N 3.1Å; F154-S156 PolarHBondContact O-N 3.26Å; F154-V157 PolarHBondContact O-N 3.41Å; F154-W158 HydrophobicContact CZ-CB 4.46Å; F154-W158 HydrophobicContact CZ-CG 4.25Å; F154-W158 WeakPolarHBondContact O-CB 3.32Å; F154-W158 PolarHBondContact O-N 3.4Å
155	N	84.3	Confident	88.4	Confident	13 Å²	13	51.2 Å²	51.2	7%	0.07	29%	0.29	C	S	.	.	H	α-helix	trans	-64.8	-40.1	-175.1	-62.8	-45	0	0	0	112	Y97 A153 F159 P413	Y97-N155 WeakPolarHBondContact CE1-O 3.45Å; A153-N155 PolarHBondContact O-N 3.3Å; N155-F159 WeakPolarHBondContact O-CB 3.49Å; N155-F159 PolarHBondContact O-N 3.28Å; N155-P413 HydrophobicContact CB-CB 4.24Å; N155-P413 HydrophobicContact CB-CG 3.91Å
156	S	85.4	Confident	88.5	Confident	24 Å²	24	49.3 Å²	49.3	17%	0.168	27%	0.27	C	S	.	.	H	α-helix	trans	-68.6	-43.7	178	-53.6	0	0	0	0	111.9	A153 F154 F159 Y160 T415	A153-S156 PolarHBondContact O-N 3.46Å; F154-S156 PolarHBondContact O-N 3.26Å; S156-F159 WeakPolarHBondContact O-CB 3.4Å; S156-F159 PolarHBondContact O-N 3.42Å; S156-Y160 WeakPolarHBondContact O-CD2 3.45Å; S156-Y160 PolarHBondContact O-N 3.46Å; S156-T415 WeakPolarHBondContact OG-CG2 3.3Å
157	V	90.1	Very high	88.6	Confident	75 Å²	75	51.8 Å²	51.8	46%	0.455	28%	0.28	S	S	.	.	H	α-helix	trans	-64	-46.8	176.1	171.6	0	0	0	0	110.3	A153 F154 F159 Y160 F161	A153-V157 HydrophobicContact CB-CG2 4.48Å; A153-V157 WeakPolarHBondContact O-CB 3.43Å; A153-V157 VanDerWaalsContact O-CG2 3.29Å; A153-V157 WeakPolarHBondContact O-CG2 3.49Å; A153-V157 PolarHBondContact O-N 2.61Å; F154-V157 PolarHBondContact O-N 3.41Å; V157-F159 VanDerWaalsContact C-N 3.26Å; V157-F159 PolarHBondContact O-N 2.95Å; V157-Y160 PolarHBondContact O-N 3.48Å; V157-Y160 VanDerWaalsContact O-N 3.08Å; V157-F161 HydrophobicContact CG1-CD2 3.94Å; V157-F161 HydrophobicContact CG1-CE2 3.84Å; V157-F161 WeakPolarHBondContact O-CD2 3.4Å; V157-F161 PolarHBondContact O-N 2.82Å
158	W	92.5	Very high	88.9	Confident	31 Å²	31	53 Å²	53	12%	0.117	29%	0.288	C	S	.	.	H	α-helix	trans	-66.4	-29.1	-178.3	-158.4	-118.3	0	0	0	112.3	Y97 F101 A104 F154 Y160 F161 G162 L401 M404	Y97-W158 HydrophobicContact CD1-CB 4.08Å; Y97-W158 AromaticContact CD1-CD1 3.64Å; Y97-W158 HydrophobicContact CD1-CG 4.26Å; Y97-W158 HydrophobicContact CE1-CB 4.35Å; F101-W158 HydrophobicContact CB-CZ2 4Å; F101-W158 AromaticContact CD2-CD2 3.82Å; F101-W158 HydrophobicContact CD2-CD2 3.82Å; F101-W158 AromaticContact CD2-CE2 3.59Å; F101-W158 AromaticContact CD2-CE3 3.84Å; F101-W158 HydrophobicContact CD2-CE3 3.84Å; F101-W158 AromaticContact CD2-CH2 3.49Å; F101-W158 HydrophobicContact CD2-CH2 3.49Å; F101-W158 VanDerWaalsContact CD2-CH2 3.49Å; F101-W158 AromaticContact CD2-CZ2 3.46Å; F101-W158 HydrophobicContact CD2-CZ2 3.46Å; F101-W158 VanDerWaalsContact CD2-CZ2 3.46Å; F101-W158 AromaticContact CD2-CZ3 3.67Å; F101-W158 HydrophobicContact CD2-CZ3 3.67Å; F101-W158 HydrophobicContact CE2-CE3 4.25Å; F101-W158 AromaticContact CE2-CH2 3.95Å; F101-W158 HydrophobicContact CE2-CH2 3.95Å; F101-W158 HydrophobicContact CE2-CZ2 4.37Å; F101-W158 AromaticContact CE2-CZ3 3.88Å; F101-W158 HydrophobicContact CE2-CZ3 3.88Å; F101-W158 HydrophobicContact CG-CZ2 4.16Å; A104-W158 HydrophobicContact CB-CH2 4.32Å; A104-W158 HydrophobicContact CB-CZ2 3.91Å; F154-W158 HydrophobicContact CZ-CB 4.46Å; F154-W158 HydrophobicContact CZ-CG 4.25Å; F154-W158 WeakPolarHBondContact O-CB 3.32Å; F154-W158 PolarHBondContact O-N 3.4Å; W158-Y160 PolarHBondContact O-N 3.02Å; W158-F161 HydrophobicContact CD2-CB 4.45Å; W158-F161 HydrophobicContact CE3-CB 4.03Å; W158-F161 HydrophobicContact CE3-CD2 4.18Å; W158-F161 HydrophobicContact CE3-CG 4.18Å; W158-F161 HydrophobicContact CZ3-CB 4.22Å; W158-F161 HydrophobicContact CZ3-CD2 4.42Å; W158-F161 HydrophobicContact CZ3-CG 4.17Å; W158-F161 PolarHBondContact O-N 3.41Å; W158-G162 PolarHBondContact O-N 3.39Å; W158-L401 HydrophobicContact CH2-CD2 4.25Å; W158-L401 HydrophobicContact CZ2-CD2 3.58Å; W158-M404 HydrophobicContact CG-CE 4.46Å; W158-M404 HydrophobicContact CG-SD 4.29Å; W158-M404 PolarHBondContact NE1-SD 3.15Å
159	F	91.5	Very high	89.1	Confident	0 Å²	0	45.3 Å²	45.3	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-58.9	-43.4	170	169.5	-95.3	0	0	0	112	Y97 N155 S156 V157 G162 L163 M405 Y411 Q412	Y97-F159 HydrophobicContact CE1-CB 4.15Å; Y97-F159 WeakPolarHBondContact OH-CD2 3.26Å; N155-F159 WeakPolarHBondContact O-CB 3.49Å; N155-F159 PolarHBondContact O-N 3.28Å; S156-F159 WeakPolarHBondContact O-CB 3.4Å; S156-F159 PolarHBondContact O-N 3.42Å; V157-F159 VanDerWaalsContact C-N 3.26Å; V157-F159 PolarHBondContact O-N 2.95Å; F159-G162 CarbonylContact O-C 3.55Å; F159-G162 WeakPolarHBondContact O-CA 3.4Å; F159-G162 PolarHBondContact O-N 3.24Å; F159-L163 HydrophobicContact CD1-CD1 4.01Å; F159-L163 HydrophobicContact CD1-CG 4.37Å; F159-L163 HydrophobicContact CE1-CD1 3.38Å; F159-L163 HydrophobicContact CE1-CG 3.96Å; F159-L163 HydrophobicContact CE2-CG 4.45Å; F159-L163 HydrophobicContact CZ-CD1 3.75Å; F159-L163 HydrophobicContact CZ-CD2 4.15Å; F159-L163 HydrophobicContact CZ-CG 4Å; F159-L163 PolarHBondContact O-N 3.42Å; F159-M405 HydrophobicContact CD2-CE 3.49Å; F159-M405 VanDerWaalsContact CD2-CE 3.49Å; F159-M405 HydrophobicContact CD2-SD 4.14Å; F159-M405 HydrophobicContact CE2-CE 3.4Å; F159-M405 VanDerWaalsContact CE2-CE 3.4Å; F159-M405 HydrophobicContact CG-CE 4.4Å; F159-M405 HydrophobicContact CZ-CE 4.25Å; F159-Y411 WeakPolarHBondContact CD2-O 3.37Å; F159-Y411 WeakPolarHBondContact CE2-O 3.32Å; F159-Q412 HydrophobicContact CD1-CB 4.49Å; F159-Q412 HydrophobicContact CD1-CG 4.11Å; F159-Q412 HydrophobicContact CE1-CB 4.01Å; F159-Q412 HydrophobicContact CE1-CG 3.95Å; F159-Q412 HydrophobicContact CE2-CB 4.05Å; F159-Q412 HydrophobicContact CZ-CB 3.79Å; F159-Q412 HydrophobicContact CZ-CG 4.25Å
160	Y	92.9	Very high	89.5	Confident	120 Å²	120	43.8 Å²	43.8	47%	0.471	25%	0.246	S	C	.	.	H	α-helix	trans	-69.1	-38.7	177.5	-69.6	-72.6	0	0	0	112.7	S156 V157 W158 G162 L163 V164	S156-Y160 WeakPolarHBondContact O-CD2 3.45Å; S156-Y160 PolarHBondContact O-N 3.46Å; V157-Y160 PolarHBondContact O-N 3.48Å; V157-Y160 VanDerWaalsContact O-N 3.08Å; W158-Y160 PolarHBondContact O-N 3.02Å; Y160-G162 VanDerWaalsContact C-N 3.26Å; Y160-G162 PolarHBondContact O-N 3.15Å; Y160-L163 HydrophobicContact CD1-CD1 4.06Å; Y160-L163 HydrophobicContact CE1-CD1 4.46Å; Y160-L163 PolarHBondContact O-N 3.01Å; Y160-V164 WeakPolarHBondContact O-CG2 3.38Å; Y160-V164 PolarHBondContact O-N 3.11Å
161	F	94.6	Very high	90.1	Very high	122 Å²	122	40.4 Å²	40.4	54%	0.535	22%	0.222	S	C	.	.	H	α-helix	trans	-59.1	-41.8	169.5	-85	-83.8	0	0	0	111.3	V157 W158 V164 G165	V157-F161 HydrophobicContact CG1-CD2 3.94Å; V157-F161 HydrophobicContact CG1-CE2 3.84Å; V157-F161 WeakPolarHBondContact O-CD2 3.4Å; V157-F161 PolarHBondContact O-N 2.82Å; W158-F161 HydrophobicContact CD2-CB 4.45Å; W158-F161 HydrophobicContact CE3-CB 4.03Å; W158-F161 HydrophobicContact CE3-CD2 4.18Å; W158-F161 HydrophobicContact CE3-CG 4.18Å; W158-F161 HydrophobicContact CZ3-CB 4.22Å; W158-F161 HydrophobicContact CZ3-CD2 4.42Å; W158-F161 HydrophobicContact CZ3-CG 4.17Å; W158-F161 PolarHBondContact O-N 3.41Å; F161-V164 PolarHBondContact O-N 2.93Å; F161-G165 PolarHBondContact O-N 2.98Å
162	G	95.5	Very high	90.9	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-58.6	-47.1	173	0	0	0	0	0	112.8	W158 F159 Y160 G165 S166	W158-G162 PolarHBondContact O-N 3.39Å; F159-G162 CarbonylContact O-C 3.55Å; F159-G162 WeakPolarHBondContact O-CA 3.4Å; F159-G162 PolarHBondContact O-N 3.24Å; Y160-G162 VanDerWaalsContact C-N 3.26Å; Y160-G162 PolarHBondContact O-N 3.15Å; G162-G165 PolarHBondContact O-N 3.3Å; G162-S166 WeakPolarHBondContact O-CB 3.06Å; G162-S166 PolarHBondContact O-N 2.89Å; G162-S166 PolarHBondContact O-OG 3.39Å
163	L	94.6	Very high	91.8	Very high	10 Å²	10	36.6 Å²	36.6	5%	0.052	19%	0.192	C	C	.	.	H	α-helix	trans	-58.5	-50.6	177.3	-76.9	178.7	0	0	0	111.9	F159 Y160 S166 F167 M405 W410 P425 A426 V429	F159-L163 HydrophobicContact CD1-CD1 4.01Å; F159-L163 HydrophobicContact CD1-CG 4.37Å; F159-L163 HydrophobicContact CE1-CD1 3.38Å; F159-L163 HydrophobicContact CE1-CG 3.96Å; F159-L163 HydrophobicContact CE2-CG 4.45Å; F159-L163 HydrophobicContact CZ-CD1 3.75Å; F159-L163 HydrophobicContact CZ-CD2 4.15Å; F159-L163 HydrophobicContact CZ-CG 4Å; F159-L163 PolarHBondContact O-N 3.42Å; Y160-L163 HydrophobicContact CD1-CD1 4.06Å; Y160-L163 HydrophobicContact CE1-CD1 4.46Å; Y160-L163 PolarHBondContact O-N 3.01Å; L163-S166 PolarHBondContact O-N 3.31Å; L163-F167 WeakPolarHBondContact O-CB 3.35Å; L163-F167 PolarHBondContact O-N 3.48Å; L163-M405 HydrophobicContact CD2-CE 3.66Å; L163-M405 HydrophobicContact CG-CE 3.91Å; L163-W410 HydrophobicContact CD2-CE3 3.61Å; L163-W410 HydrophobicContact CD2-CZ3 3.6Å; L163-P425 HydrophobicContact CD1-CB 4.07Å; L163-A426 HydrophobicContact CD2-CB 4.37Å; L163-V429 HydrophobicContact CD2-CG2 4.42Å
164	V	95.6	Very high	92.2	Very high	93 Å²	93	33.5 Å²	33.5	56%	0.564	17%	0.166	S	C	*	.	H	α-helix	trans	-66.6	-45.3	-179.1	176.6	0	0	0	0	110.9	Y160 F161 S166 F167 I168	Y160-V164 WeakPolarHBondContact O-CG2 3.38Å; Y160-V164 PolarHBondContact O-N 3.11Å; F161-V164 PolarHBondContact O-N 2.93Å; V164-S166 VanDerWaalsContact C-N 3.33Å; V164-S166 PolarHBondContact O-N 2.9Å; V164-F167 WeakPolarHBondContact O-CB 3.31Å; V164-F167 PolarHBondContact O-N 3Å; V164-I168 HydrophobicContact CG1-CD1 4.31Å; V164-I168 WeakPolarHBondContact O-CG1 3.4Å; V164-I168 PolarHBondContact O-N 3.27Å
165	G	95.6	Very high	92.3	Very high	3 Å²	3	32.5 Å²	32.5	3%	0.031	16%	0.162	C	C	.	.	H	α-helix	trans	-61.9	-41.9	177.8	0	0	0	0	0	112.4	F161 G162 I168 F169	F161-G165 PolarHBondContact O-N 2.98Å; G162-G165 PolarHBondContact O-N 3.3Å; G165-I168 PolarHBondContact O-N 3.47Å; G165-F169 WeakPolarHBondContact O-CB 3.48Å; G165-F169 PolarHBondContact O-N 3.04Å
166	S	95	Very high	92.5	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-66.6	-39	177.1	-58.2	0	0	0	0	112.2	G162 L163 V164 I168 F169 I170 L401 Y402 M405	G162-S166 WeakPolarHBondContact O-CB 3.06Å; G162-S166 PolarHBondContact O-N 2.89Å; G162-S166 PolarHBondContact O-OG 3.39Å; L163-S166 PolarHBondContact O-N 3.31Å; V164-S166 VanDerWaalsContact C-N 3.33Å; V164-S166 PolarHBondContact O-N 2.9Å; S166-I168 VanDerWaalsContact C-N 3.34Å; S166-I168 PolarHBondContact O-N 3.24Å; S166-F169 PolarHBondContact O-N 2.94Å; S166-I170 WeakPolarHBondContact O-CB 3.46Å; S166-I170 WeakPolarHBondContact O-CD1 3.42Å; S166-I170 WeakPolarHBondContact O-CG1 3.12Å; S166-I170 PolarHBondContact O-N 3.41Å; S166-L401 PolarHBondContact OG-O 2.56Å; S166-Y402 VanDerWaalsContact OG-CA 3.32Å; S166-Y402 WeakPolarHBondContact OG-CA 3.18Å; S166-M405 VanDerWaalsContact OG-CG 3.22Å; S166-M405 WeakPolarHBondContact OG-CG 3.18Å
167	F	95.1	Very high	92.7	Very high	55 Å²	55	31.9 Å²	31.9	24%	0.241	16%	0.157	C	C	.	.	H	α-helix	trans	-55.6	-50	174.1	172.8	-100.4	0	0	0	111.3	L163 V164 I170 L171 V429 C432 S433 L436	L163-F167 WeakPolarHBondContact O-CB 3.35Å; L163-F167 PolarHBondContact O-N 3.48Å; V164-F167 WeakPolarHBondContact O-CB 3.31Å; V164-F167 PolarHBondContact O-N 3Å; F167-I170 PolarHBondContact O-N 3.45Å; F167-L171 HydrophobicContact CD1-CD1 4.34Å; F167-L171 HydrophobicContact CE1-CD1 3.77Å; F167-L171 HydrophobicContact CZ-CD1 3.9Å; F167-L171 WeakPolarHBondContact O-CG 3.24Å; F167-L171 PolarHBondContact O-N 2.89Å; F167-V429 HydrophobicContact CB-CG1 3.77Å; F167-V429 HydrophobicContact CD2-CG1 4.19Å; F167-V429 HydrophobicContact CG-CG1 4.48Å; F167-C432 HydrophobicContact CE2-CB 4.18Å; F167-S433 WeakPolarHBondContact CD2-OG 3.48Å; F167-S433 WeakPolarHBondContact CE2-OG 3.39Å; F167-S433 PolarHBondContact O-OG 3.44Å; F167-L436 HydrophobicContact CE2-CD1 4.04Å; F167-L436 HydrophobicContact CZ-CD1 3.51Å
168	I	94.5	Very high	92.6	Very high	60 Å²	60	28.5 Å²	28.5	31%	0.308	14%	0.136	S	C	.	.	H	α-helix	trans	-65.7	-42.3	178.8	-57.1	167.9	0	0	0	110.2	V164 G165 S166 I170 L171 I172 L398	V164-I168 HydrophobicContact CG1-CD1 4.31Å; V164-I168 WeakPolarHBondContact O-CG1 3.4Å; V164-I168 PolarHBondContact O-N 3.27Å; G165-I168 PolarHBondContact O-N 3.47Å; S166-I168 VanDerWaalsContact C-N 3.34Å; S166-I168 PolarHBondContact O-N 3.24Å; I168-I170 PolarHBondContact O-N 3.42Å; I168-L171 WeakPolarHBondContact O-CB 3.27Å; I168-L171 PolarHBondContact O-N 3.29Å; I168-I172 HydrophobicContact CG2-CD1 4.13Å; I168-I172 PolarHBondContact O-N 3.01Å; I168-L398 HydrophobicContact CB-CD1 4.08Å; I168-L398 HydrophobicContact CB-CD2 4.25Å; I168-L398 HydrophobicContact CD1-CD2 4.35Å; I168-L398 HydrophobicContact CG2-CD1 3.51Å; I168-L398 HydrophobicContact CG2-CD2 4.46Å
169	F	94.4	Very high	92.3	Very high	1 Å²	1	27.1 Å²	27.1	0%	0.004	13%	0.131	C	C	.	.	H	α-helix	trans	-61.7	-43.2	177.9	-175.2	-97.4	0	0	0	112.5	G165 S166 L171 I172 Q173 F334 H395 L398 A399 Y402	G165-F169 WeakPolarHBondContact O-CB 3.48Å; G165-F169 PolarHBondContact O-N 3.04Å; S166-F169 PolarHBondContact O-N 2.94Å; F169-L171 VanDerWaalsContact C-N 3.27Å; F169-L171 PolarHBondContact O-N 3.46Å; F169-I172 PolarHBondContact O-N 2.87Å; F169-Q173 HydrophobicContact CD1-CB 4.44Å; F169-Q173 HydrophobicContact CE1-CB 4.22Å; F169-Q173 VanDerWaalsContact O-CB 3.23Å; F169-Q173 WeakPolarHBondContact O-CB 2.89Å; F169-Q173 PolarHBondContact O-N 3.38Å; F169-F334 AromaticContact CE1-CD2 3.81Å; F169-F334 HydrophobicContact CE1-CD2 3.81Å; F169-F334 HydrophobicContact CE1-CE2 4.46Å; F169-F334 AromaticContact CZ-CD2 3.58Å; F169-F334 HydrophobicContact CZ-CD2 3.58Å; F169-F334 AromaticContact CZ-CE2 3.94Å; F169-F334 HydrophobicContact CZ-CE2 3.94Å; F169-H395 AromaticContact CE2-CE1 3.46Å; F169-H395 VanDerWaalsContact CE2-CE1 3.46Å; F169-H395 WeakPolarHBondContact CE2-CE1 3.27Å; F169-H395 AromaticContact CE2-NE2 4Å; F169-L398 HydrophobicContact CB-CB 4.13Å; F169-L398 HydrophobicContact CD2-CB 4.19Å; F169-A399 VanDerWaalsContact CD2-CA 3.45Å; F169-A399 HydrophobicContact CD2-CB 3.85Å; F169-A399 VanDerWaalsContact CE2-CA 3.45Å; F169-A399 HydrophobicContact CE2-CB 3.35Å; F169-A399 HydrophobicContact CZ-CB 4.03Å; F169-Y402 VanDerWaalsContact CD1-CB 3.44Å; F169-Y402 AromaticContact CD1-CD1 3.74Å; F169-Y402 HydrophobicContact CD1-CD1 3.74Å; F169-Y402 AromaticContact CD1-CD2 3.74Å; F169-Y402 HydrophobicContact CD1-CD2 3.74Å; F169-Y402 HydrophobicContact CD1-CE1 4.44Å; F169-Y402 HydrophobicContact CD1-CE2 4.43Å; F169-Y402 AromaticContact CD1-CG 3.33Å; F169-Y402 HydrophobicContact CD1-CG 3.33Å; F169-Y402 AromaticContact CE1-CD1 3.61Å; F169-Y402 HydrophobicContact CE1-CD1 3.61Å; F169-Y402 HydrophobicContact CE1-CD2 4.37Å; F169-Y402 HydrophobicContact CE1-CE1 4.13Å; F169-Y402 AromaticContact CE1-CG 3.74Å; F169-Y402 HydrophobicContact CE1-CG 3.74Å; F169-Y402 HydrophobicContact CG-CG 4.17Å
170	I	93.7	Very high	92.2	Very high	9 Å²	9	29.2 Å²	29.2	5%	0.046	14%	0.14	C	C	.	.	H	α-helix	trans	-61.8	-37.1	178.1	-68.6	164.5	0	0	0	110.6	S166 F167 I168 Q173 L174 Y402 W410 K430	S166-I170 WeakPolarHBondContact O-CB 3.46Å; S166-I170 WeakPolarHBondContact O-CD1 3.42Å; S166-I170 WeakPolarHBondContact O-CG1 3.12Å; S166-I170 PolarHBondContact O-N 3.41Å; F167-I170 PolarHBondContact O-N 3.45Å; I168-I170 PolarHBondContact O-N 3.42Å; I170-Q173 PolarHBondContact O-N 3.35Å; I170-L174 WeakPolarHBondContact O-CB 3.4Å; I170-L174 PolarHBondContact O-N 3.42Å; I170-Y402 HydrophobicContact CD1-CD2 4.42Å; I170-Y402 HydrophobicContact CD1-CE2 4.18Å; I170-Y402 HydrophobicContact CG1-CD2 4.01Å; I170-Y402 HydrophobicContact CG1-CE2 3.84Å; I170-W410 HydrophobicContact CD1-CH2 3.99Å; I170-W410 HydrophobicContact CD1-CZ2 4.14Å; I170-K430 HydrophobicContact CD1-CG 4.46Å
171	L	92.2	Very high	92	Very high	30 Å²	30	23.6 Å²	23.6	16%	0.157	12%	0.119	C	C	.	.	H	α-helix	trans	-64.3	-47.9	174.1	-67.1	176.8	0	0	0	111.6	F167 I168 F169 Q173 L174 I175 L436	F167-L171 HydrophobicContact CD1-CD1 4.34Å; F167-L171 HydrophobicContact CE1-CD1 3.77Å; F167-L171 HydrophobicContact CZ-CD1 3.9Å; F167-L171 WeakPolarHBondContact O-CG 3.24Å; F167-L171 PolarHBondContact O-N 2.89Å; I168-L171 WeakPolarHBondContact O-CB 3.27Å; I168-L171 PolarHBondContact O-N 3.29Å; F169-L171 VanDerWaalsContact C-N 3.27Å; F169-L171 PolarHBondContact O-N 3.46Å; L171-Q173 VanDerWaalsContact C-N 3.33Å; L171-Q173 PolarHBondContact O-N 3.1Å; L171-L174 PolarHBondContact O-N 3.5Å; L171-I175 WeakPolarHBondContact O-CD1 3.34Å; L171-I175 WeakPolarHBondContact O-CG1 3.34Å; L171-I175 PolarHBondContact O-N 3.45Å; L171-L436 HydrophobicContact CD1-CD1 4.5Å; L171-L436 HydrophobicContact CD2-CB 3.85Å; L171-L436 HydrophobicContact CD2-CD1 4.49Å
172	I	90.3	Very high	91.6	Very high	13 Å²	13	18.5 Å²	18.5	7%	0.067	10%	0.097	C	C	.	.	H	α-helix	trans	-61.3	-43.7	175.8	-67	170	0	0	0	111	I168 F169 L174 I175 L176 M355 F391 H395 L398	I168-I172 HydrophobicContact CG2-CD1 4.13Å; I168-I172 PolarHBondContact O-N 3.01Å; F169-I172 PolarHBondContact O-N 2.87Å; I172-L174 VanDerWaalsContact C-N 3.27Å; I172-L174 PolarHBondContact O-N 3.03Å; I172-I175 WeakPolarHBondContact O-CB 3.28Å; I172-I175 PolarHBondContact O-N 3.01Å; I172-L176 HydrophobicContact CG2-CD1 4.15Å; I172-L176 HydrophobicContact CG2-CG 4.44Å; I172-L176 WeakPolarHBondContact O-CG 3.31Å; I172-L176 PolarHBondContact O-N 3.45Å; I172-M355 HydrophobicContact CG2-CE 3.5Å; I172-M355 HydrophobicContact CG2-SD 3.81Å; I172-F391 HydrophobicContact CD1-CZ 4.45Å; I172-H395 WeakPolarHBondContact CG2-ND1 3.42Å; I172-L398 HydrophobicContact CD1-CD1 3.74Å
173	Q	91.8	Very high	91.1	Very high	1 Å²	1	19.6 Å²	19.6	1%	0.005	10%	0.104	C	C	.	.	H	α-helix	trans	-58.2	-42.1	177.7	179.1	175	69.6	0	0	111	F169 I170 L171 L176 L177 Y276 I333 C337	F169-Q173 HydrophobicContact CD1-CB 4.44Å; F169-Q173 HydrophobicContact CE1-CB 4.22Å; F169-Q173 VanDerWaalsContact O-CB 3.23Å; F169-Q173 WeakPolarHBondContact O-CB 2.89Å; F169-Q173 PolarHBondContact O-N 3.38Å; I170-Q173 PolarHBondContact O-N 3.35Å; L171-Q173 VanDerWaalsContact C-N 3.33Å; L171-Q173 PolarHBondContact O-N 3.1Å; Q173-L176 PolarHBondContact O-N 2.87Å; Q173-L177 WeakPolarHBondContact O-CG 3.42Å; Q173-L177 PolarHBondContact O-N 2.81Å; Q173-Y276 PolarHBondContact OE1-OH 3.35Å; Q173-Y276 VanDerWaalsContact OE1-OH 3.08Å; Q173-I333 HydrophobicContact CG-CG2 4.21Å; Q173-C337 HydrophobicContact CG-CB 4.16Å
174	L	90.3	Very high	90.8	Very high	5 Å²	5	21.5 Å²	21.5	3%	0.026	11%	0.111	C	C	.	.	H	α-helix	trans	-69	-40.6	176.1	-179	67.6	0	0	0	112.5	I170 L171 I172 L176 L177 I178 I273 Y276	I170-L174 WeakPolarHBondContact O-CB 3.4Å; I170-L174 PolarHBondContact O-N 3.42Å; L171-L174 PolarHBondContact O-N 3.5Å; I172-L174 VanDerWaalsContact C-N 3.27Å; I172-L174 PolarHBondContact O-N 3.03Å; L174-L176 PolarHBondContact O-N 3.47Å; L174-L177 PolarHBondContact O-N 2.62Å; L174-L177 VanDerWaalsContact O-N 3.11Å; L174-I178 HydrophobicContact CD1-CD1 4.48Å; L174-I178 HydrophobicContact CD1-CG1 4.37Å; L174-I178 HydrophobicContact CD2-CD1 4.45Å; L174-I178 HydrophobicContact CG-CD1 3.96Å; L174-I178 HydrophobicContact CG-CG1 4.31Å; L174-I178 VanDerWaalsContact O-CG1 3.32Å; L174-I178 WeakPolarHBondContact O-CG1 3.44Å; L174-I178 PolarHBondContact O-N 2.59Å; L174-I273 HydrophobicContact CD1-CD1 4.02Å; L174-Y276 HydrophobicContact CB-CE1 4.24Å; L174-Y276 HydrophobicContact CD1-CD1 3.53Å; L174-Y276 HydrophobicContact CD1-CE1 3.64Å; L174-Y276 HydrophobicContact CD1-CG 4.47Å; L174-Y276 HydrophobicContact CG-CE1 4.41Å
175	I	88.1	Confident	90.5	Very high	17 Å²	17	17.3 Å²	17.3	9%	0.087	9%	0.085	C	C	.	.	H	α-helix	trans	-56.7	-44.3	174.3	-70.1	159.5	0	0	0	110.1	L171 I172 L177 I178 D179 V351 L354 M355 L440	L171-I175 WeakPolarHBondContact O-CD1 3.34Å; L171-I175 WeakPolarHBondContact O-CG1 3.34Å; L171-I175 PolarHBondContact O-N 3.45Å; I172-I175 WeakPolarHBondContact O-CB 3.28Å; I172-I175 PolarHBondContact O-N 3.01Å; I175-L177 PolarHBondContact O-N 3.19Å; I175-I178 PolarHBondContact O-N 3.15Å; I175-D179 WeakPolarHBondContact O-CB 3.42Å; I175-D179 PolarHBondContact O-N 3.16Å; I175-V351 HydrophobicContact CG2-CG1 3.41Å; I175-V351 VanDerWaalsContact CG2-CG1 3.41Å; I175-L354 HydrophobicContact CB-CD2 4.48Å; I175-L354 HydrophobicContact CD1-CD2 3.37Å; I175-L354 HydrophobicContact CD1-CG 4.21Å; I175-L354 HydrophobicContact CG1-CD2 3.67Å; I175-L354 HydrophobicContact CG2-CD2 3.95Å; I175-M355 HydrophobicContact CG2-CG 3.88Å; I175-M355 HydrophobicContact CG2-SD 3.99Å; I175-L440 HydrophobicContact CD1-CD1 4.26Å; I175-L440 HydrophobicContact CG1-CD1 4.25Å
176	L	88.8	Confident	90.1	Very high	10 Å²	10	20.4 Å²	20.4	5%	0.052	10%	0.098	C	C	.	.	H	α-helix	trans	-62.7	-39.7	175.5	-69.8	170.8	0	0	0	112.4	I172 Q173 L174 D179 F180 C337 Y340 A341 M355	I172-L176 HydrophobicContact CG2-CD1 4.15Å; I172-L176 HydrophobicContact CG2-CG 4.44Å; I172-L176 WeakPolarHBondContact O-CG 3.31Å; I172-L176 PolarHBondContact O-N 3.45Å; Q173-L176 PolarHBondContact O-N 2.87Å; L174-L176 PolarHBondContact O-N 3.47Å; L176-D179 PolarHBondContact O-N 2.95Å; L176-F180 WeakPolarHBondContact O-CB 3.3Å; L176-F180 PolarHBondContact O-N 3.48Å; L176-C337 HydrophobicContact CD1-CB 4.23Å; L176-Y340 HydrophobicContact CB-CD1 4.36Å; L176-Y340 HydrophobicContact CD2-CD1 4.26Å; L176-Y340 WeakPolarHBondContact O-CE1 3.44Å; L176-A341 HydrophobicContact CD1-CB 3.96Å; L176-A341 HydrophobicContact CD2-CB 4.22Å; L176-M355 HydrophobicContact CD2-CE 4.12Å; L176-M355 HydrophobicContact CG-CE 4.35Å
177	L	90.5	Very high	89.8	Confident	15 Å²	15	24.1 Å²	24.1	8%	0.079	12%	0.117	C	C	.	.	H	α-helix	trans	-67.7	-41.6	176.1	-75.1	173.2	0	0	0	112.8	Q173 L174 I175 D179 F180 A181 Y276 I333 F336	Q173-L177 WeakPolarHBondContact O-CG 3.42Å; Q173-L177 PolarHBondContact O-N 2.81Å; L174-L177 PolarHBondContact O-N 2.62Å; L174-L177 VanDerWaalsContact O-N 3.11Å; I175-L177 PolarHBondContact O-N 3.19Å; L177-D179 VanDerWaalsContact C-N 3.28Å; L177-D179 PolarHBondContact O-N 2.8Å; L177-F180 PolarHBondContact O-N 3.06Å; L177-A181 WeakPolarHBondContact O-CB 3.36Å; L177-A181 PolarHBondContact O-N 3.37Å; L177-Y276 HydrophobicContact CD1-CD1 4.31Å; L177-Y276 HydrophobicContact CD1-CD2 3.42Å; L177-Y276 VanDerWaalsContact CD1-CD2 3.42Å; L177-Y276 HydrophobicContact CD1-CE1 4.4Å; L177-Y276 HydrophobicContact CD1-CE2 3.56Å; L177-Y276 HydrophobicContact CD1-CG 3.81Å; L177-I333 HydrophobicContact CD1-CG2 4.17Å; L177-F336 HydrophobicContact CD2-CD1 4.14Å; L177-F336 HydrophobicContact CD2-CE1 3.94Å
178	I	87.8	Confident	89.5	Confident	4 Å²	4	24 Å²	24	2%	0.021	12%	0.115	C	C	.	.	H	α-helix	trans	-57.4	-48.3	174.5	-72.2	165.3	0	0	0	109.3	L174 I175 A181 H182 I273 Y441	L174-I178 HydrophobicContact CD1-CD1 4.48Å; L174-I178 HydrophobicContact CD1-CG1 4.37Å; L174-I178 HydrophobicContact CD2-CD1 4.45Å; L174-I178 HydrophobicContact CG-CD1 3.96Å; L174-I178 HydrophobicContact CG-CG1 4.31Å; L174-I178 VanDerWaalsContact O-CG1 3.32Å; L174-I178 WeakPolarHBondContact O-CG1 3.44Å; L174-I178 PolarHBondContact O-N 2.59Å; I175-I178 PolarHBondContact O-N 3.15Å; I178-A181 WeakPolarHBondContact O-CB 3.46Å; I178-A181 PolarHBondContact O-N 3.03Å; I178-A181 VanDerWaalsContact O-N 3.14Å; I178-H182 PolarHBondContact O-CD2 2.73Å; I178-H182 PolarHBondContact O-N 3.26Å; I178-I273 HydrophobicContact CB-CD1 4.41Å; I178-I273 HydrophobicContact CG1-CD1 3.56Å; I178-I273 HydrophobicContact CG1-CG1 4.2Å; I178-Y441 HydrophobicContact CD1-CD2 4.25Å; I178-Y441 HydrophobicContact CD1-CG 4.45Å; I178-Y441 HydrophobicContact CG1-CD2 3.97Å; I178-Y441 HydrophobicContact CG1-CG 4.47Å; I178-Y441 HydrophobicContact CG2-CD2 3.91Å; I178-Y441 HydrophobicContact CG2-CE2 4.46Å
179	D	85.4	Confident	89.2	Confident	2 Å²	2	22.2 Å²	22.2	1%	0.011	11%	0.106	C	C	.	.	H	α-helix	trans	-70.6	-37.2	-176.2	-157.7	-1.3	0	0	0	112.6	I175 L176 L177 A181 H182 S183 R344 N348 V351	I175-D179 WeakPolarHBondContact O-CB 3.42Å; I175-D179 PolarHBondContact O-N 3.16Å; L176-D179 PolarHBondContact O-N 2.95Å; L177-D179 VanDerWaalsContact C-N 3.28Å; L177-D179 PolarHBondContact O-N 2.8Å; D179-A181 VanDerWaalsContact C-N 3.33Å; D179-H182 PolarHBondContact O-N 3.18Å; D179-S183 WeakPolarHBondContact O-CB 3.5Å; D179-S183 PolarHBondContact O-N 3.1Å; D179-R344 IonicContact OD1-CZ 3.62Å; D179-R344 IonicContact OD1-NH1 3.5Å; D179-R344 IonicContact OD1-NH2 3.76Å; D179-R344 PolarHBondContact OD1-NH2 3.37Å; D179-R344 IonicContact OD2-CZ 3.89Å; D179-R344 IonicContact OD2-NH1 3Å; D179-R344 PolarHBondContact OD2-NH1 3.31Å; D179-R344 IonicContact OD2-NH2 2.86Å; D179-R344 PolarHBondContact OD2-NH2 3.3Å; D179-N348 VanDerWaalsContact OD1-CB 3.31Å; D179-N348 WeakPolarHBondContact OD1-CB 3.41Å; D179-N348 PolarHBondContact OD1-ND2 3.19Å; D179-V351 HydrophobicContact CB-CB 4.15Å; D179-V351 HydrophobicContact CB-CG1 3.83Å; D179-V351 HydrophobicContact CB-CG2 3.94Å; D179-V351 WeakPolarHBondContact OD2-CB 3.26Å; D179-V351 WeakPolarHBondContact OD2-CG1 3.48Å
180	F	89.2	Confident	88.9	Confident	44 Å²	44	25.2 Å²	25.2	19%	0.193	12%	0.121	C	C	.	.	H	α-helix	trans	-57.6	-46	167	169.1	-109.2	0	0	0	111.9	L176 L177 H182 S183 W184 L272 F336 Y340	L176-F180 WeakPolarHBondContact O-CB 3.3Å; L176-F180 PolarHBondContact O-N 3.48Å; L177-F180 PolarHBondContact O-N 3.06Å; F180-H182 VanDerWaalsContact C-N 3.33Å; F180-H182 PolarHBondContact O-N 2.83Å; F180-S183 PolarHBondContact O-N 3.49Å; F180-W184 HydrophobicContact CD1-CE3 4.49Å; F180-W184 AromaticContact CE1-CE3 3.45Å; F180-W184 HydrophobicContact CE1-CE3 3.45Å; F180-W184 VanDerWaalsContact CE1-CE3 3.45Å; F180-W184 AromaticContact CE1-CZ3 3.82Å; F180-W184 HydrophobicContact CE1-CZ3 3.82Å; F180-W184 HydrophobicContact CE2-CE3 4.27Å; F180-W184 HydrophobicContact CZ-CD2 4.19Å; F180-W184 AromaticContact CZ-CE3 3.31Å; F180-W184 HydrophobicContact CZ-CE3 3.31Å; F180-W184 AromaticContact CZ-CZ3 3.75Å; F180-W184 HydrophobicContact CZ-CZ3 3.75Å; F180-W184 WeakPolarHBondContact O-CB 3.39Å; F180-W184 PolarHBondContact O-N 3.46Å; F180-L272 HydrophobicContact CD1-CD2 4.02Å; F180-L272 HydrophobicContact CE1-CD2 4.1Å; F180-F336 AromaticContact CD1-CE1 3.99Å; F180-F336 HydrophobicContact CD1-CE1 3.99Å; F180-F336 AromaticContact CD1-CZ 3.76Å; F180-F336 HydrophobicContact CD1-CZ 3.76Å; F180-F336 HydrophobicContact CD2-CE1 4.49Å; F180-F336 AromaticContact CD2-CZ 3.72Å; F180-F336 HydrophobicContact CD2-CZ 3.72Å; F180-F336 HydrophobicContact CE1-CE1 4.27Å; F180-F336 AromaticContact CE1-CZ 3.74Å; F180-F336 HydrophobicContact CE1-CZ 3.74Å; F180-F336 HydrophobicContact CE2-CE2 4.35Å; F180-F336 AromaticContact CE2-CZ 3.71Å; F180-F336 HydrophobicContact CE2-CZ 3.71Å; F180-F336 HydrophobicContact CG-CE1 4.09Å; F180-F336 AromaticContact CG-CZ 3.74Å; F180-F336 HydrophobicContact CG-CZ 3.74Å; F180-F336 HydrophobicContact CZ-CE2 4.32Å; F180-F336 AromaticContact CZ-CZ 3.71Å; F180-F336 HydrophobicContact CZ-CZ 3.71Å; F180-Y340 VanDerWaalsContact CA-OH 3.25Å; F180-Y340 WeakPolarHBondContact CA-OH 3.42Å; F180-Y340 HydrophobicContact CB-CD1 4.48Å; F180-Y340 HydrophobicContact CB-CE1 3.86Å; F180-Y340 HydrophobicContact CB-CE2 4.24Å; F180-Y340 HydrophobicContact CD2-CD2 4.4Å; F180-Y340 AromaticContact CD2-CE2 3.94Å; F180-Y340 HydrophobicContact CD2-CE2 3.94Å; F180-Y340 PolarHBondContact N-OH 3.05Å
181	A	89.5	Confident	88.6	Confident	2 Å²	2	27.2 Å²	27.2	2%	0.017	13%	0.131	C	C	.	.	H	α-helix	trans	-62.4	-41.4	178.9	0	0	0	0	0	111.7	L177 I178 D179 N185 Q269 L272	L177-A181 WeakPolarHBondContact O-CB 3.36Å; L177-A181 PolarHBondContact O-N 3.37Å; I178-A181 WeakPolarHBondContact O-CB 3.46Å; I178-A181 PolarHBondContact O-N 3.03Å; I178-A181 VanDerWaalsContact O-N 3.14Å; D179-A181 VanDerWaalsContact C-N 3.33Å; A181-N185 WeakPolarHBondContact O-CB 3.42Å; A181-N185 PolarHBondContact O-N 3.5Å; A181-Q269 HydrophobicContact CB-CB 4.12Å; A181-Q269 HydrophobicContact CB-CG 3.93Å; A181-Q269 WeakPolarHBondContact O-CG 3.37Å; A181-L272 HydrophobicContact CB-CD2 3.96Å
182	H	85.8	Confident	88.3	Confident	15 Å²	15	25.9 Å²	25.9	7%	0.069	12%	0.124	C	C	.	.	H	α-helix	trans	-64	-47.5	175.1	-77.9	-67.6	0	0	0	112.1	I178 D179 F180 N185 K186 Q262 Q269 Y441	I178-H182 PolarHBondContact O-CD2 2.73Å; I178-H182 PolarHBondContact O-N 3.26Å; D179-H182 PolarHBondContact O-N 3.18Å; F180-H182 VanDerWaalsContact C-N 3.33Å; F180-H182 PolarHBondContact O-N 2.83Å; H182-N185 PolarHBondContact O-N 3.08Å; H182-K186 WeakPolarHBondContact O-CB 3.39Å; H182-K186 PolarHBondContact O-N 3.47Å; H182-Q262 PolarHBondContact CE1-NE2 3.48Å; H182-Q262 PolarHBondContact ND1-NE2 3.26Å; H182-Q269 VanDerWaalsContact CE1-CD 3.46Å; H182-Q269 PolarHBondContact CE1-OE1 2.94Å; H182-Q269 PolarHBondContact ND1-NE2 2.72Å; H182-Q269 PolarHBondContact ND1-OE1 3.21Å; H182-Y441 AromaticContact NE2-CE2 3.8Å
183	S	85.9	Confident	88.1	Confident	23 Å²	23	30.8 Å²	30.8	16%	0.161	15%	0.147	C	C	.	.	H	α-helix	trans	-61	-45.5	177.9	-178.4	0	0	0	0	111.9	D179 F180 K186 I187	D179-S183 WeakPolarHBondContact O-CB 3.5Å; D179-S183 PolarHBondContact O-N 3.1Å; F180-S183 PolarHBondContact O-N 3.49Å; S183-K186 PolarHBondContact O-N 3.19Å; S183-I187 WeakPolarHBondContact O-CB 3.33Å; S183-I187 WeakPolarHBondContact O-CD1 3.47Å; S183-I187 VanDerWaalsContact O-CG1 3.24Å; S183-I187 WeakPolarHBondContact O-CG1 3.31Å; S183-I187 PolarHBondContact O-N 3.41Å
184	W	88.1	Confident	88	Confident	50 Å²	50	38.1 Å²	38.1	19%	0.189	18%	0.182	C	C	.	.	H	α-helix	trans	-59.2	-52.3	176.1	-173.8	-7.9	0	0	0	110.8	F180 K186 I187 W188 F207 L268	F180-W184 HydrophobicContact CD1-CE3 4.49Å; F180-W184 AromaticContact CE1-CE3 3.45Å; F180-W184 HydrophobicContact CE1-CE3 3.45Å; F180-W184 VanDerWaalsContact CE1-CE3 3.45Å; F180-W184 AromaticContact CE1-CZ3 3.82Å; F180-W184 HydrophobicContact CE1-CZ3 3.82Å; F180-W184 HydrophobicContact CE2-CE3 4.27Å; F180-W184 HydrophobicContact CZ-CD2 4.19Å; F180-W184 AromaticContact CZ-CE3 3.31Å; F180-W184 HydrophobicContact CZ-CE3 3.31Å; F180-W184 AromaticContact CZ-CZ3 3.75Å; F180-W184 HydrophobicContact CZ-CZ3 3.75Å; F180-W184 WeakPolarHBondContact O-CB 3.39Å; F180-W184 PolarHBondContact O-N 3.46Å; W184-K186 VanDerWaalsContact C-N 3.34Å; W184-K186 PolarHBondContact O-N 3.32Å; W184-I187 PolarHBondContact O-N 2.94Å; W184-W188 AromaticContact CD1-CD1 3.44Å; W184-W188 VanDerWaalsContact CD1-CD1 3.44Å; W184-W188 AromaticContact CD1-CD2 3.72Å; W184-W188 AromaticContact CD1-CE2 3.61Å; W184-W188 AromaticContact CD1-CG 3.64Å; W184-W188 AromaticContact CD1-NE1 3.41Å; W184-W188 HydrophobicContact CZ2-CH2 4.25Å; W184-W188 HydrophobicContact CZ2-CZ2 4.18Å; W184-W188 AromaticContact NE1-CD1 3.72Å; W184-W188 AromaticContact NE1-CD2 3.27Å; W184-W188 VanDerWaalsContact NE1-CD2 3.27Å; W184-W188 AromaticContact NE1-CE2 3Å; W184-W188 AromaticContact NE1-CE3 3.79Å; W184-W188 AromaticContact NE1-CG 3.74Å; W184-W188 AromaticContact NE1-CH2 3.83Å; W184-W188 AromaticContact NE1-CZ2 3.32Å; W184-W188 VanDerWaalsContact NE1-CZ2 3.32Å; W184-W188 AromaticContact NE1-NE1 3.28Å; W184-W188 PolarHBondContact O-N 3.35Å; W184-F207 HydrophobicContact CH2-CD1 4.17Å; W184-F207 HydrophobicContact CH2-CE1 4.26Å; W184-F207 HydrophobicContact CH2-CG 4.36Å; W184-F207 HydrophobicContact CZ2-CD1 4.4Å; W184-F207 HydrophobicContact CZ2-CD2 4.04Å; W184-F207 HydrophobicContact CZ2-CE1 4.47Å; W184-F207 HydrophobicContact CZ2-CE2 4.15Å; W184-F207 HydrophobicContact CZ2-CG 4.2Å; W184-F207 HydrophobicContact CZ2-CZ 4.35Å; W184-L268 HydrophobicContact CD2-CD2 4.41Å; W184-L268 HydrophobicContact CG-CD2 4.28Å
185	N	89	Confident	87.6	Confident	4 Å²	4	41.9 Å²	41.9	2%	0.021	21%	0.205	C	C	.	.	H	α-helix	trans	-58.7	-46.1	-179.6	-167.1	71.8	0	0	0	111.7	A181 H182 W188 V189 H264 L268 Q269	A181-N185 WeakPolarHBondContact O-CB 3.42Å; A181-N185 PolarHBondContact O-N 3.5Å; H182-N185 PolarHBondContact O-N 3.08Å; N185-W188 PolarHBondContact O-N 3.38Å; N185-V189 WeakPolarHBondContact O-CB 3.25Å; N185-V189 VanDerWaalsContact O-CG2 3.22Å; N185-V189 WeakPolarHBondContact O-CG2 3.4Å; N185-V189 PolarHBondContact O-N 2.87Å; N185-H264 PolarHBondContact ND2-O 3.29Å; N185-L268 HydrophobicContact CB-CD2 4.37Å; N185-Q269 HydrophobicContact CB-CG 4.09Å; N185-Q269 VanDerWaalsContact CB-NE2 3.26Å; N185-Q269 PolarHBondContact ND2-NE2 2.93Å
186	K	86.9	Confident	87.1	Confident	68 Å²	68	48.4 Å²	48.4	30%	0.296	24%	0.235	S	C	.	.	H	α-helix	trans	-57.4	-54.7	178.9	-179.5	177.2	177.7	177.7	0	111.3	H182 S183 W184 W188 V189 E190 H264	H182-K186 WeakPolarHBondContact O-CB 3.39Å; H182-K186 PolarHBondContact O-N 3.47Å; S183-K186 PolarHBondContact O-N 3.19Å; W184-K186 VanDerWaalsContact C-N 3.34Å; W184-K186 PolarHBondContact O-N 3.32Å; K186-W188 VanDerWaalsContact C-N 3.28Å; K186-W188 PolarHBondContact O-N 2.68Å; K186-V189 PolarHBondContact O-N 2.68Å; K186-E190 WeakPolarHBondContact CE-OE1 3.46Å; K186-E190 HydrophobicContact CG-CG 4.34Å; K186-E190 WeakPolarHBondContact CG-OE1 3.45Å; K186-E190 IonicContact NZ-OE1 3.08Å; K186-E190 WeakPolarHBondContact O-CB 3.45Å; K186-E190 VanDerWaalsContact O-CG 3.32Å; K186-E190 WeakPolarHBondContact O-CG 3.31Å; K186-E190 PolarHBondContact O-N 3.37Å; K186-H264 HydrophobicContact CB-CB 4.46Å
187	I	87.8	Confident	86.8	Confident	78 Å²	78	51.5 Å²	51.5	40%	0.4	25%	0.252	S	S	.	.	H	α-helix	trans	-58	-42.6	-178.5	-67.8	165.5	0	0	0	110.9	S183 W184 N191	S183-I187 WeakPolarHBondContact O-CB 3.33Å; S183-I187 WeakPolarHBondContact O-CD1 3.47Å; S183-I187 VanDerWaalsContact O-CG1 3.24Å; S183-I187 WeakPolarHBondContact O-CG1 3.31Å; S183-I187 PolarHBondContact O-N 3.41Å; W184-I187 PolarHBondContact O-N 2.94Å; I187-N191 WeakPolarHBondContact CG2-ND2 3.43Å; I187-N191 WeakPolarHBondContact O-CB 3.49Å; I187-N191 PolarHBondContact O-N 3.42Å; I187-N191 VanDerWaalsContact O-N 3.08Å; I187-N191 PolarHBondContact O-ND2 3.24Å
188	W	89.9	Confident	86.5	Confident	54 Å²	54	59.2 Å²	59.2	21%	0.205	28%	0.284	C	S	.	.	H	α-helix	trans	-75.3	-36.5	-176.4	-79.8	36.2	0	0	0	112.7	W184 N185 K186 A192 W200 L204 F207	W184-W188 AromaticContact CD1-CD1 3.44Å; W184-W188 VanDerWaalsContact CD1-CD1 3.44Å; W184-W188 AromaticContact CD1-CD2 3.72Å; W184-W188 AromaticContact CD1-CE2 3.61Å; W184-W188 AromaticContact CD1-CG 3.64Å; W184-W188 AromaticContact CD1-NE1 3.41Å; W184-W188 HydrophobicContact CZ2-CH2 4.25Å; W184-W188 HydrophobicContact CZ2-CZ2 4.18Å; W184-W188 AromaticContact NE1-CD1 3.72Å; W184-W188 AromaticContact NE1-CD2 3.27Å; W184-W188 VanDerWaalsContact NE1-CD2 3.27Å; W184-W188 AromaticContact NE1-CE2 3Å; W184-W188 AromaticContact NE1-CE3 3.79Å; W184-W188 AromaticContact NE1-CG 3.74Å; W184-W188 AromaticContact NE1-CH2 3.83Å; W184-W188 AromaticContact NE1-CZ2 3.32Å; W184-W188 VanDerWaalsContact NE1-CZ2 3.32Å; W184-W188 AromaticContact NE1-NE1 3.28Å; W184-W188 PolarHBondContact O-N 3.35Å; N185-W188 PolarHBondContact O-N 3.38Å; K186-W188 VanDerWaalsContact C-N 3.28Å; K186-W188 PolarHBondContact O-N 2.68Å; W188-A192 VanDerWaalsContact O-CB 3.28Å; W188-A192 WeakPolarHBondContact O-CB 3.33Å; W188-A192 PolarHBondContact O-N 3.23Å; W188-W200 HydrophobicContact CB-CE3 4.45Å; W188-W200 AromaticContact CD1-CZ3 3.91Å; W188-W200 AromaticContact CD2-CE3 3.76Å; W188-W200 HydrophobicContact CD2-CE3 3.76Å; W188-W200 AromaticContact CD2-CZ3 3.84Å; W188-W200 HydrophobicContact CD2-CZ3 3.84Å; W188-W200 AromaticContact CE2-CZ3 3.62Å; W188-W200 HydrophobicContact CE3-CE3 4.11Å; W188-W200 HydrophobicContact CE3-CZ3 4.5Å; W188-W200 AromaticContact CG-CE3 3.94Å; W188-W200 HydrophobicContact CG-CE3 3.94Å; W188-W200 HydrophobicContact CG-CZ3 4.03Å; W188-W200 HydrophobicContact CZ2-CZ3 4.11Å; W188-W200 AromaticContact NE1-CZ3 3.67Å; W188-L204 HydrophobicContact CB-CD1 4.01Å; W188-L204 HydrophobicContact CE3-CB 4.34Å; W188-F207 AromaticContact CH2-CD2 3.97Å; W188-F207 HydrophobicContact CH2-CD2 3.97Å; W188-F207 AromaticContact CH2-CE2 3.67Å; W188-F207 HydrophobicContact CH2-CE2 3.67Å; W188-F207 AromaticContact CZ3-CD2 3.95Å; W188-F207 HydrophobicContact CZ3-CD2 3.95Å; W188-F207 HydrophobicContact CZ3-CE2 4.1Å
189	V	87.8	Confident	86.5	Confident	21 Å²	21	63 Å²	63	13%	0.127	31%	0.31	C	S	.	.	H	α-helix	trans	-67.2	-47.3	175.2	170.7	0	0	0	0	110.5	N185 K186 N191 A192 E193 L204	N185-V189 WeakPolarHBondContact O-CB 3.25Å; N185-V189 VanDerWaalsContact O-CG2 3.22Å; N185-V189 WeakPolarHBondContact O-CG2 3.4Å; N185-V189 PolarHBondContact O-N 2.87Å; K186-V189 PolarHBondContact O-N 2.68Å; V189-N191 PolarHBondContact O-N 2.52Å; V189-A192 WeakPolarHBondContact O-CB 3.18Å; V189-A192 PolarHBondContact O-N 2.8Å; V189-A192 VanDerWaalsContact O-N 3.08Å; V189-E193 HydrophobicContact CG1-CG 4.49Å; V189-E193 WeakPolarHBondContact O-CG 3.48Å; V189-E193 PolarHBondContact O-N 2.98Å; V189-L204 HydrophobicContact CG2-CD1 4.13Å
190	E	87.5	Confident	86.7	Confident	65 Å²	65	66.8 Å²	66.8	30%	0.304	32%	0.324	S	S	.	.	H	α-helix	trans	-57.2	-49.3	176.6	-73.4	172.8	166.5	0	0	111.1	K186 A192 E193 E194	K186-E190 WeakPolarHBondContact CE-OE1 3.46Å; K186-E190 HydrophobicContact CG-CG 4.34Å; K186-E190 WeakPolarHBondContact CG-OE1 3.45Å; K186-E190 IonicContact NZ-OE1 3.08Å; K186-E190 WeakPolarHBondContact O-CB 3.45Å; K186-E190 VanDerWaalsContact O-CG 3.32Å; K186-E190 WeakPolarHBondContact O-CG 3.31Å; K186-E190 PolarHBondContact O-N 3.37Å; E190-A192 VanDerWaalsContact C-N 3.26Å; E190-A192 PolarHBondContact O-N 3.39Å; E190-E193 PolarHBondContact O-N 3.27Å; E190-E194 WeakPolarHBondContact O-CB 3.37Å; E190-E194 WeakPolarHBondContact O-CG 3.32Å; E190-E194 PolarHBondContact O-N 2.76Å
191	N	88.5	Confident	86.4	Confident	50 Å²	50	69.9 Å²	69.9	27%	0.267	34%	0.338	S	S	.	.	H	α-helix	trans	-62.3	-33.1	177	-79.9	-56.5	0	0	0	113.1	I187 V189 T195 W200	I187-N191 WeakPolarHBondContact CG2-ND2 3.43Å; I187-N191 WeakPolarHBondContact O-CB 3.49Å; I187-N191 PolarHBondContact O-N 3.42Å; I187-N191 VanDerWaalsContact O-N 3.08Å; I187-N191 PolarHBondContact O-ND2 3.24Å; V189-N191 PolarHBondContact O-N 2.52Å; N191-T195 WeakPolarHBondContact O-CB 3.47Å; N191-T195 PolarHBondContact O-N 3.46Å; N191-T195 PolarHBondContact O-OG1 3.49Å; N191-W200 HydrophobicContact CB-CD2 4.16Å; N191-W200 HydrophobicContact CB-CG 4.38Å; N191-W200 HydrophobicContact CB-CZ2 4.23Å
192	A	86	Confident	86.5	Confident	2 Å²	2	72.3 Å²	72.3	2%	0.017	36%	0.358	C	S	.	.	H	α-helix	trans	-69.7	-40.1	177.4	0	0	0	0	0	112	W188 V189 E190 Q196 W200 F201	W188-A192 VanDerWaalsContact O-CB 3.28Å; W188-A192 WeakPolarHBondContact O-CB 3.33Å; W188-A192 PolarHBondContact O-N 3.23Å; V189-A192 WeakPolarHBondContact O-CB 3.18Å; V189-A192 PolarHBondContact O-N 2.8Å; V189-A192 VanDerWaalsContact O-N 3.08Å; E190-A192 VanDerWaalsContact C-N 3.26Å; E190-A192 PolarHBondContact O-N 3.39Å; A192-Q196 WeakPolarHBondContact O-CA 3.36Å; A192-Q196 PolarHBondContact O-N 3.38Å; A192-W200 HydrophobicContact CB-CB 3.57Å; A192-W200 HydrophobicContact CB-CG 4.4Å; A192-F201 HydrophobicContact CB-CD2 3.68Å; A192-F201 HydrophobicContact CB-CE1 4.45Å; A192-F201 HydrophobicContact CB-CE2 3.45Å; A192-F201 VanDerWaalsContact CB-CE2 3.45Å; A192-F201 HydrophobicContact CB-CG 4.29Å; A192-F201 HydrophobicContact CB-CZ 3.86Å
193	E	86	Confident	86.7	Confident	116 Å²	116	72.4 Å²	72.4	54%	0.542	36%	0.363	S	S	.	.	H	α-helix	trans	-70.6	-44.8	178	-70.8	177.3	177.4	0	0	111.7	V189 E190 Q196	V189-E193 HydrophobicContact CG1-CG 4.49Å; V189-E193 WeakPolarHBondContact O-CG 3.48Å; V189-E193 PolarHBondContact O-N 2.98Å; E190-E193 PolarHBondContact O-N 3.27Å; E193-Q196 PolarHBondContact O-NE2 2.65Å
194	E	88.4	Confident	86.9	Confident	156 Å²	156	72.8 Å²	72.8	73%	0.729	36%	0.363	S	S	*	.	H	α-helix	trans	-71.3	-46.7	-178.9	-70.9	-177.5	174.1	0	0	112.9	E190 Q196	E190-E194 WeakPolarHBondContact O-CB 3.37Å; E190-E194 WeakPolarHBondContact O-CG 3.32Å; E190-E194 PolarHBondContact O-N 2.76Å; E194-Q196 VanDerWaalsContact C-N 3.34Å
195	T	82.5	Confident	87.1	Confident	83 Å²	83	75.6 Å²	75.6	51%	0.509	38%	0.382	S	S	.	.	H	α-helix	trans	-83.8	-12.5	-174.5	-43.6	0	0	0	0	112	N191 N197	N191-T195 WeakPolarHBondContact O-CB 3.47Å; N191-T195 PolarHBondContact O-N 3.46Å; N191-T195 PolarHBondContact O-OG1 3.49Å; T195-N197 HydrophobicContact CG2-CB 3.91Å; T195-N197 PolarHBondContact O-N 3.18Å
196	Q	77.2	Confident	87.3	Confident	154 Å²	154	79 Å²	79	72%	0.72	41%	0.405	S	S	*	.			trans	51.2	19.6	-170	-66.2	-70.4	-55.1	0	0	113.5	A192 E193 E194 K198	A192-Q196 WeakPolarHBondContact O-CA 3.36Å; A192-Q196 PolarHBondContact O-N 3.38Å; E193-Q196 PolarHBondContact O-NE2 2.65Å; E194-Q196 VanDerWaalsContact C-N 3.34Å; Q196-K198 PolarHBondContact O-N 2.96Å
197	N	83.3	Confident	87.7	Confident	76 Å²	76	79.2 Å²	79.2	41%	0.406	41%	0.406	S	S	.	.			trans	-86.6	109.4	-177.2	-175.5	-4.7	0	0	0	109.5	T195 C199 W200	T195-N197 HydrophobicContact CG2-CB 3.91Å; T195-N197 PolarHBondContact O-N 3.18Å; N197-C199 PolarHBondContact O-N 3.2Å; N197-C199 WeakPolarHBondContact OD1-CB 3.42Å; N197-C199 PolarHBondContact OD1-N 3.27Å; N197-W200 PolarHBondContact O-N 3.04Å; N197-W200 VanDerWaalsContact O-N 3.16Å
198	K	84.2	Confident	88	Confident	177 Å²	177	75.8 Å²	75.8	77%	0.77	39%	0.389	S	S	*	.	H	α-helix	trans	-57.5	-17.7	178.6	-63	-178.4	-179.4	177.8	0	113.8	Q196 W200 F201 A202	Q196-K198 PolarHBondContact O-N 2.96Å; K198-W200 VanDerWaalsContact C-N 3.29Å; K198-W200 PolarHBondContact O-N 3.08Å; K198-F201 PolarHBondContact O-N 2.87Å; K198-A202 WeakPolarHBondContact O-CB 3.38Å; K198-A202 PolarHBondContact O-N 3.4Å
199	C	88.7	Confident	88.3	Confident	84 Å²	84	77.4 Å²	77.4	57%	0.568	41%	0.405	S	S	*	.	H	α-helix	trans	-60.6	-35.5	176.5	-168.2	0	0	0	0	112.8	N197 A202 G203	N197-C199 PolarHBondContact O-N 3.2Å; N197-C199 WeakPolarHBondContact OD1-CB 3.42Å; N197-C199 PolarHBondContact OD1-N 3.27Å; C199-A202 PolarHBondContact O-N 2.89Å; C199-G203 PolarHBondContact O-N 2.98Å
200	W	88.4	Confident	88.7	Confident	80 Å²	80	80.5 Å²	80.5	30%	0.303	42%	0.42	S	S	.	.	H	α-helix	trans	-66.6	-45.3	178.6	-71.5	116.8	0	0	0	111.9	W188 N191 A192 N197 K198 G203 L204	W188-W200 HydrophobicContact CB-CE3 4.45Å; W188-W200 AromaticContact CD1-CZ3 3.91Å; W188-W200 AromaticContact CD2-CE3 3.76Å; W188-W200 HydrophobicContact CD2-CE3 3.76Å; W188-W200 AromaticContact CD2-CZ3 3.84Å; W188-W200 HydrophobicContact CD2-CZ3 3.84Å; W188-W200 AromaticContact CE2-CZ3 3.62Å; W188-W200 HydrophobicContact CE3-CE3 4.11Å; W188-W200 HydrophobicContact CE3-CZ3 4.5Å; W188-W200 AromaticContact CG-CE3 3.94Å; W188-W200 HydrophobicContact CG-CE3 3.94Å; W188-W200 HydrophobicContact CG-CZ3 4.03Å; W188-W200 HydrophobicContact CZ2-CZ3 4.11Å; W188-W200 AromaticContact NE1-CZ3 3.67Å; N191-W200 HydrophobicContact CB-CD2 4.16Å; N191-W200 HydrophobicContact CB-CG 4.38Å; N191-W200 HydrophobicContact CB-CZ2 4.23Å; A192-W200 HydrophobicContact CB-CB 3.57Å; A192-W200 HydrophobicContact CB-CG 4.4Å; N197-W200 PolarHBondContact O-N 3.04Å; N197-W200 VanDerWaalsContact O-N 3.16Å; K198-W200 VanDerWaalsContact C-N 3.29Å; K198-W200 PolarHBondContact O-N 3.08Å; W200-G203 PolarHBondContact O-N 3.22Å; W200-L204 WeakPolarHBondContact O-CB 3.39Å; W200-L204 PolarHBondContact O-N 2.9Å
201	F	84	Confident	89.2	Confident	109 Å²	109	78.3 Å²	78.3	48%	0.478	41%	0.41	S	S	.	.	H	α-helix	trans	-62.2	-43.2	173.3	-79.1	-69.7	0	0	0	112.3	A192 K198 G203 L204 L205	A192-F201 HydrophobicContact CB-CD2 3.68Å; A192-F201 HydrophobicContact CB-CE1 4.45Å; A192-F201 HydrophobicContact CB-CE2 3.45Å; A192-F201 VanDerWaalsContact CB-CE2 3.45Å; A192-F201 HydrophobicContact CB-CG 4.29Å; A192-F201 HydrophobicContact CB-CZ 3.86Å; K198-F201 PolarHBondContact O-N 2.87Å; F201-G203 VanDerWaalsContact C-N 3.32Å; F201-G203 PolarHBondContact O-N 3.48Å; F201-L204 PolarHBondContact O-N 3.45Å; F201-L205 WeakPolarHBondContact O-CB 3.44Å; F201-L205 PolarHBondContact O-N 2.93Å
202	A	89.7	Confident	89.6	Confident	54 Å²	54	78.8 Å²	78.8	45%	0.446	41%	0.409	S	S	.	.	H	α-helix	trans	-61.2	-41.6	177	0	0	0	0	0	111.6	K198 C199 S206	K198-A202 WeakPolarHBondContact O-CB 3.38Å; K198-A202 PolarHBondContact O-N 3.4Å; C199-A202 PolarHBondContact O-N 2.89Å; A202-S206 VanDerWaalsContact O-CB 3.32Å; A202-S206 WeakPolarHBondContact O-CB 3.32Å; A202-S206 PolarHBondContact O-N 3.2Å; A202-S206 PolarHBondContact O-OG 3.46Å
203	G	91.3	Very high	90.1	Very high	17 Å²	17	81 Å²	81	18%	0.175	43%	0.427	C	S	.	.	H	α-helix	trans	-61.4	-49.3	173.9	0	0	0	0	0	112.1	C199 W200 F201 L205 S206 F207	C199-G203 PolarHBondContact O-N 2.98Å; W200-G203 PolarHBondContact O-N 3.22Å; F201-G203 VanDerWaalsContact C-N 3.32Å; F201-G203 PolarHBondContact O-N 3.48Å; G203-L205 VanDerWaalsContact C-N 3.34Å; G203-L205 PolarHBondContact O-N 3.18Å; G203-S206 WeakPolarHBondContact O-CB 3.33Å; G203-S206 PolarHBondContact O-N 3.41Å; G203-S206 VanDerWaalsContact O-N 3.13Å; G203-F207 VanDerWaalsContact O-CD2 3.27Å; G203-F207 WeakPolarHBondContact O-CD2 3.46Å; G203-F207 PolarHBondContact O-N 3.27Å
204	L	90	Very high	90.6	Very high	30 Å²	30	79.5 Å²	79.5	16%	0.157	42%	0.422	C	S	.	.	H	α-helix	trans	-59.3	-44.6	-179.3	-166	126.1	0	0	0	112	W188 V189 W200 F201 T208 L268	W188-L204 HydrophobicContact CB-CD1 4.01Å; W188-L204 HydrophobicContact CE3-CB 4.34Å; V189-L204 HydrophobicContact CG2-CD1 4.13Å; W200-L204 WeakPolarHBondContact O-CB 3.39Å; W200-L204 PolarHBondContact O-N 2.9Å; F201-L204 PolarHBondContact O-N 3.45Å; L204-T208 WeakPolarHBondContact O-CB 3.46Å; L204-T208 PolarHBondContact O-N 2.94Å; L204-T208 VanDerWaalsContact O-N 3.12Å; L204-T208 PolarHBondContact O-OG1 3.24Å; L204-L268 HydrophobicContact CD1-CD2 4.06Å; L204-L268 HydrophobicContact CG-CB 4.37Å; L204-L268 HydrophobicContact CG-CD2 4.19Å
205	L	91.2	Very high	91	Very high	110 Å²	110	72.5 Å²	72.5	58%	0.576	39%	0.391	S	S	*	.	H	α-helix	trans	-63.9	-43.1	175.1	-177.8	64.8	0	0	0	111.5	F201 G203 F207 T208 V209	F201-L205 WeakPolarHBondContact O-CB 3.44Å; F201-L205 PolarHBondContact O-N 2.93Å; G203-L205 VanDerWaalsContact C-N 3.34Å; G203-L205 PolarHBondContact O-N 3.18Å; L205-F207 PolarHBondContact O-N 2.65Å; L205-T208 PolarHBondContact O-N 2.79Å; L205-V209 HydrophobicContact CD1-CG2 4.19Å; L205-V209 HydrophobicContact CG-CG2 4.38Å; L205-V209 WeakPolarHBondContact O-CG2 3.32Å; L205-V209 PolarHBondContact O-N 3.44Å
206	S	94.2	Very high	91.7	Very high	74 Å²	74	75.1 Å²	75.1	52%	0.517	40%	0.395	S	S	.	.	H	α-helix	trans	-61	-47.2	-178.8	-61	0	0	0	0	112.1	A202 G203 T208 V209 L210	A202-S206 VanDerWaalsContact O-CB 3.32Å; A202-S206 WeakPolarHBondContact O-CB 3.32Å; A202-S206 PolarHBondContact O-N 3.2Å; A202-S206 PolarHBondContact O-OG 3.46Å; G203-S206 WeakPolarHBondContact O-CB 3.33Å; G203-S206 PolarHBondContact O-N 3.41Å; G203-S206 VanDerWaalsContact O-N 3.13Å; S206-T208 VanDerWaalsContact C-N 3.35Å; S206-V209 PolarHBondContact O-N 3.09Å; S206-L210 VanDerWaalsContact O-CB 3.31Å; S206-L210 WeakPolarHBondContact O-CB 3.48Å; S206-L210 PolarHBondContact O-N 2.94Å
207	F	94.8	Very high	92.6	Very high	73 Å²	73	70.6 Å²	70.6	32%	0.32	38%	0.381	S	S	.	.	H	α-helix	trans	-64.3	-40.6	176.3	-80.1	-71.8	0	0	0	112	W184 W188 G203 L205 L210 H211 L268	W184-F207 HydrophobicContact CH2-CD1 4.17Å; W184-F207 HydrophobicContact CH2-CE1 4.26Å; W184-F207 HydrophobicContact CH2-CG 4.36Å; W184-F207 HydrophobicContact CZ2-CD1 4.4Å; W184-F207 HydrophobicContact CZ2-CD2 4.04Å; W184-F207 HydrophobicContact CZ2-CE1 4.47Å; W184-F207 HydrophobicContact CZ2-CE2 4.15Å; W184-F207 HydrophobicContact CZ2-CG 4.2Å; W184-F207 HydrophobicContact CZ2-CZ 4.35Å; W188-F207 AromaticContact CH2-CD2 3.97Å; W188-F207 HydrophobicContact CH2-CD2 3.97Å; W188-F207 AromaticContact CH2-CE2 3.67Å; W188-F207 HydrophobicContact CH2-CE2 3.67Å; W188-F207 AromaticContact CZ3-CD2 3.95Å; W188-F207 HydrophobicContact CZ3-CD2 3.95Å; W188-F207 HydrophobicContact CZ3-CE2 4.1Å; G203-F207 VanDerWaalsContact O-CD2 3.27Å; G203-F207 WeakPolarHBondContact O-CD2 3.46Å; G203-F207 PolarHBondContact O-N 3.27Å; L205-F207 PolarHBondContact O-N 2.65Å; F207-L210 PolarHBondContact O-N 2.64Å; F207-H211 PolarHBondContact O-N 3.23Å; F207-H211 PolarHBondContact O-ND1 3.15Å; F207-H211 VanDerWaalsContact O-ND1 3.14Å; F207-L268 HydrophobicContact CB-CD1 3.72Å
208	T	94.8	Very high	93.2	Very high	6 Å²	6	67.9 Å²	67.9	4%	0.037	37%	0.369	C	S	.	.	H	α-helix	trans	-60.7	-48	177.9	-57.4	0	0	0	0	111.7	L204 L205 S206 H211 Y212 L267 L268	L204-T208 WeakPolarHBondContact O-CB 3.46Å; L204-T208 PolarHBondContact O-N 2.94Å; L204-T208 VanDerWaalsContact O-N 3.12Å; L204-T208 PolarHBondContact O-OG1 3.24Å; L205-T208 PolarHBondContact O-N 2.79Å; S206-T208 VanDerWaalsContact C-N 3.35Å; T208-H211 PolarHBondContact O-N 2.88Å; T208-Y212 HydrophobicContact CG2-CD2 4.05Å; T208-Y212 HydrophobicContact CG2-CE2 3.93Å; T208-Y212 WeakPolarHBondContact O-CD2 3.31Å; T208-Y212 PolarHBondContact O-N 3.02Å; T208-Y212 VanDerWaalsContact O-N 3.17Å; T208-L267 HydrophobicContact CG2-CB 4.02Å; T208-L267 HydrophobicContact CG2-CD2 3.67Å; T208-L267 HydrophobicContact CG2-CG 3.6Å; T208-L268 WeakPolarHBondContact OG1-CA 3.5Å
209	V	96.1	Very high	93.7	Very high	88 Å²	88	59.8 Å²	59.8	53%	0.533	33%	0.334	S	S	.	.	H	α-helix	trans	-63.4	-44	177.2	171.7	0	0	0	0	110.8	L205 S206 H211 Y212 A213	L205-V209 HydrophobicContact CD1-CG2 4.19Å; L205-V209 HydrophobicContact CG-CG2 4.38Å; L205-V209 WeakPolarHBondContact O-CG2 3.32Å; L205-V209 PolarHBondContact O-N 3.44Å; S206-V209 PolarHBondContact O-N 3.09Å; V209-H211 PolarHBondContact O-N 2.95Å; V209-Y212 PolarHBondContact O-N 3.28Å; V209-A213 VanDerWaalsContact O-CB 3.29Å; V209-A213 WeakPolarHBondContact O-CB 3.39Å; V209-A213 PolarHBondContact O-N 3.38Å
210	L	96.8	Very high	94.1	Very high	87 Å²	87	58.6 Å²	58.6	46%	0.455	32%	0.324	S	S	.	.	H	α-helix	trans	-58.9	-48.7	178	177.7	63.4	0	0	0	111.7	S206 F207 Y212 A213 L214	S206-L210 VanDerWaalsContact O-CB 3.31Å; S206-L210 WeakPolarHBondContact O-CB 3.48Å; S206-L210 PolarHBondContact O-N 2.94Å; F207-L210 PolarHBondContact O-N 2.64Å; L210-Y212 PolarHBondContact O-N 2.75Å; L210-A213 PolarHBondContact O-N 3.06Å; L210-L214 HydrophobicContact CD1-CD1 4.09Å; L210-L214 HydrophobicContact CD1-CG 4.2Å; L210-L214 HydrophobicContact CG-CD1 4.07Å; L210-L214 WeakPolarHBondContact O-CB 3.48Å; L210-L214 VanDerWaalsContact O-CG 3.31Å; L210-L214 WeakPolarHBondContact O-CG 3.43Å; L210-L214 PolarHBondContact O-N 3.39Å
211	H	96.7	Very high	94.3	Very high	18 Å²	18	58.8 Å²	58.8	8%	0.083	33%	0.331	C	S	.	.	H	α-helix	trans	-62.1	-43.7	-179.5	-65.6	146.8	0	0	0	112.2	F207 T208 V209 L214 A215 S271 L275	F207-H211 PolarHBondContact O-N 3.23Å; F207-H211 PolarHBondContact O-ND1 3.15Å; F207-H211 VanDerWaalsContact O-ND1 3.14Å; T208-H211 PolarHBondContact O-N 2.88Å; V209-H211 PolarHBondContact O-N 2.95Å; H211-L214 PolarHBondContact O-N 3.3Å; H211-A215 WeakPolarHBondContact O-CB 3.37Å; H211-A215 PolarHBondContact O-N 3.47Å; H211-S271 PolarHBondContact ND1-OG 3.3Å; H211-L275 HydrophobicContact CB-CD2 4.37Å
212	Y	96.9	Very high	94.8	Very high	61 Å²	61	54.2 Å²	54.2	24%	0.239	31%	0.311	C	S	.	.	H	α-helix	trans	-68.1	-37.8	176.2	-78.9	-56.6	0	0	0	113.2	T208 V209 L210 L214 A215 F216 S250 L267 S271	T208-Y212 HydrophobicContact CG2-CD2 4.05Å; T208-Y212 HydrophobicContact CG2-CE2 3.93Å; T208-Y212 WeakPolarHBondContact O-CD2 3.31Å; T208-Y212 PolarHBondContact O-N 3.02Å; T208-Y212 VanDerWaalsContact O-N 3.17Å; V209-Y212 PolarHBondContact O-N 3.28Å; L210-Y212 PolarHBondContact O-N 2.75Å; Y212-L214 VanDerWaalsContact C-N 3.32Å; Y212-L214 PolarHBondContact O-N 3.31Å; Y212-A215 PolarHBondContact O-N 3.46Å; Y212-F216 WeakPolarHBondContact O-CB 3.48Å; Y212-F216 PolarHBondContact O-N 3.06Å; Y212-S250 VanDerWaalsContact OH-CB 3.26Å; Y212-S250 WeakPolarHBondContact OH-CB 3.45Å; Y212-S250 PolarHBondContact OH-OG 3.48Å; Y212-L267 HydrophobicContact CE2-CD1 3.78Å; Y212-L267 HydrophobicContact CE2-CD2 4.09Å; Y212-L267 HydrophobicContact CE2-CG 3.73Å; Y212-L267 VanDerWaalsContact OH-CD1 3.23Å; Y212-L267 WeakPolarHBondContact OH-CD1 3.22Å; Y212-S271 VanDerWaalsContact CE2-CB 3.42Å; Y212-S271 PolarHBondContact OH-N 3.33Å
213	A	97.3	Very high	95	Very high	49 Å²	49	55.5 Å²	55.5	41%	0.405	31%	0.305	S	S	.	.	H	α-helix	trans	-61.7	-42.9	175.4	0	0	0	0	0	111.2	V209 L210 S217	V209-A213 VanDerWaalsContact O-CB 3.29Å; V209-A213 WeakPolarHBondContact O-CB 3.39Å; V209-A213 PolarHBondContact O-N 3.38Å; L210-A213 PolarHBondContact O-N 3.06Å; A213-S217 VanDerWaalsContact O-CB 3.3Å; A213-S217 WeakPolarHBondContact O-CB 3.28Å; A213-S217 PolarHBondContact O-N 3.23Å; A213-S217 PolarHBondContact O-OG 3.29Å
214	L	97	Very high	95.1	Very high	84 Å²	84	59.7 Å²	59.7	44%	0.44	32%	0.322	S	S	.	.	H	α-helix	trans	-65.6	-43.9	174.9	-70.1	173.8	0	0	0	111.8	L210 H211 Y212 S217 A218 L275	L210-L214 HydrophobicContact CD1-CD1 4.09Å; L210-L214 HydrophobicContact CD1-CG 4.2Å; L210-L214 HydrophobicContact CG-CD1 4.07Å; L210-L214 WeakPolarHBondContact O-CB 3.48Å; L210-L214 VanDerWaalsContact O-CG 3.31Å; L210-L214 WeakPolarHBondContact O-CG 3.43Å; L210-L214 PolarHBondContact O-N 3.39Å; H211-L214 PolarHBondContact O-N 3.3Å; Y212-L214 VanDerWaalsContact C-N 3.32Å; Y212-L214 PolarHBondContact O-N 3.31Å; L214-S217 PolarHBondContact O-N 3.21Å; L214-A218 WeakPolarHBondContact O-CB 3.4Å; L214-A218 PolarHBondContact O-N 2.98Å; L214-L275 HydrophobicContact CB-CD1 3.79Å; L214-L275 HydrophobicContact CD1-CD2 4.35Å
215	A	96.4	Very high	95	Very high	8 Å²	8	63.4 Å²	63.4	7%	0.066	34%	0.335	C	S	.	.	H	α-helix	trans	-62.9	-44.9	178.1	0	0	0	0	0	111.8	H211 Y212 A218 V219 L275 M278	H211-A215 WeakPolarHBondContact O-CB 3.37Å; H211-A215 PolarHBondContact O-N 3.47Å; Y212-A215 PolarHBondContact O-N 3.46Å; A215-A218 WeakPolarHBondContact O-CB 3.39Å; A215-A218 PolarHBondContact O-N 3.42Å; A215-V219 WeakPolarHBondContact O-CG2 3.49Å; A215-V219 PolarHBondContact O-N 2.9Å; A215-L275 HydrophobicContact CB-CD1 4.45Å; A215-M278 HydrophobicContact CB-CG 3.98Å
216	F	96.2	Very high	94.9	Very high	138 Å²	138	59 Å²	59	61%	0.605	31%	0.31	S	S	*	.	H	α-helix	trans	-63.5	-44.8	176	-179.7	-99.2	0	0	0	111.8	Y212 A218 V219 V220	Y212-F216 WeakPolarHBondContact O-CB 3.48Å; Y212-F216 PolarHBondContact O-N 3.06Å; F216-A218 VanDerWaalsContact C-N 3.29Å; F216-A218 PolarHBondContact O-N 2.9Å; F216-V219 WeakPolarHBondContact O-CB 3.36Å; F216-V219 PolarHBondContact O-N 3.12Å; F216-V220 HydrophobicContact CD1-CG2 4.31Å; F216-V220 HydrophobicContact CE1-CG2 3.88Å; F216-V220 HydrophobicContact CZ-CG2 4.03Å; F216-V220 WeakPolarHBondContact O-CG2 2.93Å; F216-V220 PolarHBondContact O-N 3.35Å; F216-V220 VanDerWaalsContact O-N 3.07Å
217	S	96.6	Very high	94.7	Very high	59 Å²	59	56.5 Å²	56.5	41%	0.413	29%	0.292	S	S	.	.	H	α-helix	trans	-59.1	-42.1	175.7	-58.8	0	0	0	0	111.2	A213 L214 V219 V220 L221	A213-S217 VanDerWaalsContact O-CB 3.3Å; A213-S217 WeakPolarHBondContact O-CB 3.28Å; A213-S217 PolarHBondContact O-N 3.23Å; A213-S217 PolarHBondContact O-OG 3.29Å; L214-S217 PolarHBondContact O-N 3.21Å; S217-V219 PolarHBondContact O-N 2.85Å; S217-V220 PolarHBondContact O-N 3.45Å; S217-L221 VanDerWaalsContact O-CG 3.25Å; S217-L221 WeakPolarHBondContact O-CG 3.45Å; S217-L221 PolarHBondContact O-N 2.84Å
218	A	95.2	Very high	94.4	Very high	19 Å²	19	57.2 Å²	57.2	16%	0.157	30%	0.297	C	S	.	.	H	α-helix	trans	-60	-45.6	176.1	0	0	0	0	0	111.9	L214 A215 F216 V220 L221 F222 M278	L214-A218 WeakPolarHBondContact O-CB 3.4Å; L214-A218 PolarHBondContact O-N 2.98Å; A215-A218 WeakPolarHBondContact O-CB 3.39Å; A215-A218 PolarHBondContact O-N 3.42Å; F216-A218 VanDerWaalsContact C-N 3.29Å; F216-A218 PolarHBondContact O-N 2.9Å; A218-V220 VanDerWaalsContact C-N 3.35Å; A218-V220 PolarHBondContact O-N 3.21Å; A218-L221 PolarHBondContact O-N 3.43Å; A218-F222 HydrophobicContact CB-CE1 4.24Å; A218-F222 HydrophobicContact CB-CE2 4.08Å; A218-F222 HydrophobicContact CB-CZ 3.75Å; A218-F222 WeakPolarHBondContact O-CD1 3.13Å; A218-F222 WeakPolarHBondContact O-CD2 3.43Å; A218-F222 WeakPolarHBondContact O-CG 3.44Å; A218-F222 PolarHBondContact O-N 3.42Å; A218-M278 HydrophobicContact CB-CB 4.12Å; A218-M278 HydrophobicContact CB-CG 4.45Å
219	V	96.4	Very high	93.9	Very high	8 Å²	8	62.4 Å²	62.4	5%	0.048	33%	0.331	C	S	.	.	H	α-helix	trans	-57.3	-46.4	175.8	171.2	0	0	0	0	111.8	A215 F216 S217 L221 F222 Y223 I239 L243 M278	A215-V219 WeakPolarHBondContact O-CG2 3.49Å; A215-V219 PolarHBondContact O-N 2.9Å; F216-V219 WeakPolarHBondContact O-CB 3.36Å; F216-V219 PolarHBondContact O-N 3.12Å; S217-V219 PolarHBondContact O-N 2.85Å; V219-L221 VanDerWaalsContact C-N 3.35Å; V219-L221 PolarHBondContact O-N 3.03Å; V219-F222 PolarHBondContact O-N 2.92Å; V219-Y223 HydrophobicContact CG1-CD2 3.93Å; V219-Y223 HydrophobicContact CG1-CE2 3.77Å; V219-Y223 WeakPolarHBondContact O-CD2 3.43Å; V219-Y223 PolarHBondContact O-N 3.26Å; V219-Y223 VanDerWaalsContact O-N 3.08Å; V219-I239 HydrophobicContact CG1-CG2 4.05Å; V219-L243 HydrophobicContact CG1-CD2 4.27Å; V219-L243 HydrophobicContact CG2-CD1 4.35Å; V219-M278 HydrophobicContact CG2-CE 4.42Å; V219-M278 HydrophobicContact CG2-CG 4.44Å; V219-M278 HydrophobicContact CG2-SD 3.4Å; V219-M278 WeakPolarHBondContact CG2-SD 3.2Å
220	V	96.1	Very high	93.3	Very high	59 Å²	59	66 Å²	66	36%	0.358	35%	0.347	S	S	.	.	H	α-helix	trans	-59.8	-47.1	177.8	173.8	0	0	0	0	110.6	F216 S217 A218 F222 Y223 I224	F216-V220 HydrophobicContact CD1-CG2 4.31Å; F216-V220 HydrophobicContact CE1-CG2 3.88Å; F216-V220 HydrophobicContact CZ-CG2 4.03Å; F216-V220 WeakPolarHBondContact O-CG2 2.93Å; F216-V220 PolarHBondContact O-N 3.35Å; F216-V220 VanDerWaalsContact O-N 3.07Å; S217-V220 PolarHBondContact O-N 3.45Å; A218-V220 VanDerWaalsContact C-N 3.35Å; A218-V220 PolarHBondContact O-N 3.21Å; V220-F222 VanDerWaalsContact C-N 3.3Å; V220-F222 PolarHBondContact O-N 2.96Å; V220-Y223 PolarHBondContact O-N 3.3Å; V220-I224 HydrophobicContact CG1-CD1 3.79Å; V220-I224 WeakPolarHBondContact O-CG1 3.48Å; V220-I224 PolarHBondContact O-N 3.28Å; V220-I224 VanDerWaalsContact O-N 3.09Å
221	L	93.7	Very high	92.9	Very high	84 Å²	84	64.6 Å²	64.6	44%	0.44	34%	0.34	S	S	.	.	H	α-helix	trans	-63.4	-35.4	177.6	-64.7	169.7	0	0	0	112.1	S217 A218 V219 I224 Y225	S217-L221 VanDerWaalsContact O-CG 3.25Å; S217-L221 WeakPolarHBondContact O-CG 3.45Å; S217-L221 PolarHBondContact O-N 2.84Å; A218-L221 PolarHBondContact O-N 3.43Å; V219-L221 VanDerWaalsContact C-N 3.35Å; V219-L221 PolarHBondContact O-N 3.03Å; L221-I224 PolarHBondContact O-N 3.08Å; L221-Y225 HydrophobicContact CB-CD2 4.28Å; L221-Y225 HydrophobicContact CD2-CD2 4.3Å; L221-Y225 HydrophobicContact CD2-CE2 3.73Å; L221-Y225 WeakPolarHBondContact O-CB 3.25Å; L221-Y225 WeakPolarHBondContact O-CD2 3.32Å; L221-Y225 PolarHBondContact O-N 3.16Å
222	F	94.3	Very high	92.6	Very high	13 Å²	13	64 Å²	64	6%	0.057	34%	0.338	C	S	.	.	H	α-helix	trans	-65	-44.6	177.3	-60.2	-19.8	0	0	0	112	A218 V219 V220 I224 Y226 I239 M278 W282 M285	A218-F222 HydrophobicContact CB-CE1 4.24Å; A218-F222 HydrophobicContact CB-CE2 4.08Å; A218-F222 HydrophobicContact CB-CZ 3.75Å; A218-F222 WeakPolarHBondContact O-CD1 3.13Å; A218-F222 WeakPolarHBondContact O-CD2 3.43Å; A218-F222 WeakPolarHBondContact O-CG 3.44Å; A218-F222 PolarHBondContact O-N 3.42Å; V219-F222 PolarHBondContact O-N 2.92Å; V220-F222 VanDerWaalsContact C-N 3.3Å; V220-F222 PolarHBondContact O-N 2.96Å; F222-I224 VanDerWaalsContact C-N 3.34Å; F222-I224 PolarHBondContact O-N 3.01Å; F222-Y226 HydrophobicContact CD1-CD2 4.45Å; F222-Y226 WeakPolarHBondContact O-CA 3.45Å; F222-Y226 WeakPolarHBondContact O-CB 2.95Å; F222-Y226 PolarHBondContact O-N 2.85Å; F222-I239 HydrophobicContact CB-CD1 3.53Å; F222-I239 HydrophobicContact CB-CG1 3.84Å; F222-I239 HydrophobicContact CB-CG2 4.35Å; F222-I239 HydrophobicContact CD2-CG1 4.32Å; F222-M278 HydrophobicContact CE2-CB 4.11Å; F222-M278 HydrophobicContact CE2-SD 4.07Å; F222-M278 HydrophobicContact CZ-CB 4.37Å; F222-M278 VanDerWaalsContact CZ-O 3.32Å; F222-M278 WeakPolarHBondContact CZ-O 3.34Å; F222-W282 HydrophobicContact CE1-CB 3.64Å; F222-W282 AromaticContact CE1-CG 3.91Å; F222-W282 HydrophobicContact CE1-CG 3.91Å; F222-W282 HydrophobicContact CZ-CB 3.59Å; F222-W282 HydrophobicContact CZ-CG 4.33Å; F222-M285 HydrophobicContact CB-CE 3.93Å; F222-M285 HydrophobicContact CD1-CE 3.87Å; F222-M285 HydrophobicContact CD2-CE 3.88Å; F222-M285 HydrophobicContact CE1-CE 4.38Å; F222-M285 HydrophobicContact CE2-CE 4.37Å; F222-M285 HydrophobicContact CG-CE 3.62Å
223	Y	93.9	Very high	92.3	Very high	80 Å²	80	65.4 Å²	65.4	31%	0.314	35%	0.352	S	S	.	.	H	α-helix	trans	-64.7	-38.9	175.5	-79.6	-68.3	0	0	0	112.2	V219 V220 T227 I239 S240	V219-Y223 HydrophobicContact CG1-CD2 3.93Å; V219-Y223 HydrophobicContact CG1-CE2 3.77Å; V219-Y223 WeakPolarHBondContact O-CD2 3.43Å; V219-Y223 PolarHBondContact O-N 3.26Å; V219-Y223 VanDerWaalsContact O-N 3.08Å; V220-Y223 PolarHBondContact O-N 3.3Å; Y223-T227 HydrophobicContact CD1-CG2 4.06Å; Y223-T227 PolarHBondContact O-OG1 3.02Å; Y223-I239 HydrophobicContact CD1-CD1 4.43Å; Y223-I239 HydrophobicContact CD2-CG2 3.91Å; Y223-I239 HydrophobicContact CE1-CB 4.46Å; Y223-I239 HydrophobicContact CE1-CG2 4.29Å; Y223-I239 HydrophobicContact CE2-CB 4.38Å; Y223-I239 HydrophobicContact CE2-CG2 3.4Å; Y223-I239 VanDerWaalsContact CE2-CG2 3.4Å; Y223-S240 PolarHBondContact OH-OG 3.4Å
224	I	91.7	Very high	92	Very high	105 Å²	105	67.2 Å²	67.2	54%	0.538	35%	0.352	S	S	.	.	H	α-helix	trans	-67.6	-43.9	-179.6	-67.3	169.9	0	0	0	111.8	V220 L221 F222	V220-I224 HydrophobicContact CG1-CD1 3.79Å; V220-I224 WeakPolarHBondContact O-CG1 3.48Å; V220-I224 PolarHBondContact O-N 3.28Å; V220-I224 VanDerWaalsContact O-N 3.09Å; L221-I224 PolarHBondContact O-N 3.08Å; F222-I224 VanDerWaalsContact C-N 3.34Å; F222-I224 PolarHBondContact O-N 3.01Å
225	Y	88.5	Confident	91.9	Very high	108 Å²	108	63.2 Å²	63.2	42%	0.424	33%	0.331	S	S	.	.	H	α-helix	trans	-103.6	-29.2	-168.7	-64	-54.4	0	0	0	115.1	L221 P295 L300	L221-Y225 HydrophobicContact CB-CD2 4.28Å; L221-Y225 HydrophobicContact CD2-CD2 4.3Å; L221-Y225 HydrophobicContact CD2-CE2 3.73Å; L221-Y225 WeakPolarHBondContact O-CB 3.25Å; L221-Y225 WeakPolarHBondContact O-CD2 3.32Å; L221-Y225 PolarHBondContact O-N 3.16Å; Y225-P295 WeakPolarHBondContact O-CD 3.23Å; Y225-P295 VanDerWaalsContact O-CG 3.22Å; Y225-P295 WeakPolarHBondContact O-CG 3.39Å; Y225-L300 HydrophobicContact CD1-CD2 3.14Å; Y225-L300 HydrophobicContact CD1-CG 4.41Å; Y225-L300 HydrophobicContact CE1-CD2 3.57Å; Y225-L300 HydrophobicContact CG-CD1 4.36Å; Y225-L300 HydrophobicContact CG-CD2 3.76Å
226	Y	89.4	Confident	91.8	Very high	17 Å²	17	65.2 Å²	65.2	7%	0.067	34%	0.339	C	S	.	.	H	α-helix	trans	-105.4	4.6	-175.6	-70.6	-90.8	0	0	0	113.2	F222 N235 W282 M285 T286 C293	F222-Y226 HydrophobicContact CD1-CD2 4.45Å; F222-Y226 WeakPolarHBondContact O-CA 3.45Å; F222-Y226 WeakPolarHBondContact O-CB 2.95Å; F222-Y226 PolarHBondContact O-N 2.85Å; Y226-N235 WeakPolarHBondContact O-CB 3.47Å; Y226-N235 PolarHBondContact O-ND2 3.03Å; Y226-W282 AromaticContact CE2-CD1 3.86Å; Y226-W282 AromaticContact CE2-NE1 3.91Å; Y226-W282 AromaticContact CZ-CD1 3.8Å; Y226-W282 AromaticContact CZ-NE1 3.69Å; Y226-W282 PolarHBondContact OH-NE1 3.31Å; Y226-M285 HydrophobicContact CD1-CB 3.9Å; Y226-M285 HydrophobicContact CD2-CE 4.46Å; Y226-M285 HydrophobicContact CE1-CB 4.33Å; Y226-M285 HydrophobicContact CG-CB 4.43Å; Y226-M285 HydrophobicContact CG-CE 4.3Å; Y226-M285 HydrophobicContact CG-SD 4.45Å; Y226-T286 HydrophobicContact CE1-CG2 4.21Å; Y226-T286 WeakPolarHBondContact OH-CG2 3.49Å; Y226-C293 WeakPolarHBondContact CD1-O 3.19Å
227	T	90.7	Very high	91.7	Very high	23 Å²	23	61.9 Å²	61.9	14%	0.141	33%	0.329	C	S	.	.			trans	-131.7	155.6	177.4	83.6	0	0	0	0	112.4	Y223 N235 K236 I239	Y223-T227 HydrophobicContact CD1-CG2 4.06Å; Y223-T227 PolarHBondContact O-OG1 3.02Å; T227-N235 HydrophobicContact CG2-CB 4.27Å; T227-K236 HydrophobicContact CG2-CG 3.73Å; T227-I239 HydrophobicContact CG2-CD1 3.68Å
228	Q	87.6	Confident	91.6	Very high	88 Å²	88	59.3 Å²	59.3	41%	0.411	31%	0.311	S	S	.	.			trans	-127.6	155.2	171.6	-65.2	-163.8	16.9	0	0	109.7	D230 D231 K236 K292	Q228-D230 VanDerWaalsContact C-N 3.35Å; Q228-D230 PolarHBondContact O-N 3.31Å; Q228-D231 HydrophobicContact CB-CB 4.46Å; Q228-K236 WeakPolarHBondContact O-CE 3.35Å; Q228-K236 PolarHBondContact O-NZ 3.11Å; Q228-K292 PolarHBondContact NE2-O 2.92Å
229	P	84.4	Confident	91.7	Very high	115 Å²	115	58.4 Å²	58.4	75%	0.747	30%	0.303	S	S	*	.	S	Bend	trans	-52.8	-47.4	-179	-28.5	36.1	0	0	0	113.8	K236	P229-K236 PolarHBondContact O-NZ 2.88Å
230	D	84.4	Confident	91.7	Very high	164 Å²	164	59.9 Å²	59.9	88%	0.877	31%	0.314	S	S	*	.	S	Bend	trans	-104.8	0.7	-172.5	-57.2	-46.7	0	0	0	114.9	Q228	Q228-D230 VanDerWaalsContact C-N 3.35Å; Q228-D230 PolarHBondContact O-N 3.31Å
231	D	88	Confident	91.7	Very high	57 Å²	57	59.9 Å²	59.9	31%	0.305	31%	0.312	S	S	.	.	S	Bend	trans	-140.4	-173.5	-177.8	-159.5	-4	0	0	0	111.2	Q228 T233 K236	Q228-D231 HydrophobicContact CB-CB 4.46Å; D231-T233 VanDerWaalsContact C-N 3.33Å; D231-T233 PolarHBondContact O-N 2.87Å; D231-K236 VanDerWaalsContact O-CE 3.26Å; D231-K236 WeakPolarHBondContact O-CE 3.33Å; D231-K236 PolarHBondContact O-NZ 3.41Å
232	C	89.1	Confident	91.9	Very high	6 Å²	6	55.9 Å²	55.9	4%	0.041	29%	0.291	C	S	.	.			trans	62	35.9	175.9	-47.7	0	0	0	0	113.8	E234 N235 K236 C293	C232-E234 PolarHBondContact O-N 3.43Å; C232-N235 PolarHBondContact O-N 3.3Å; C232-K236 PolarHBondContact O-N 3.41Å; C232-K236 VanDerWaalsContact O-N 3.12Å; C232-C293 WeakPolarHBondContact CA-SG 3.39Å; C232-C293 HydrophobicContact CB-CB 3.72Å; C232-C293 WeakPolarHBondContact CB-SG 3.45Å; C232-C293 WeakPolarHBondContact SG-CA 3.42Å; C232-C293 WeakPolarHBondContact SG-CB 3.5Å; C232-C293 CovalentContact SG-SG 2.02Å; C232-C293 PolarHBondContact SG-SG 2.87Å
233	T	91.8	Very high	92	Very high	89 Å²	89	57.8 Å²	57.8	55%	0.546	30%	0.301	S	S	.	.	H	α-helix	trans	-56.1	-37.5	-178.3	-54	0	0	0	0	112.6	D231 K236 V237	D231-T233 VanDerWaalsContact C-N 3.33Å; D231-T233 PolarHBondContact O-N 2.87Å; T233-K236 WeakPolarHBondContact O-CB 3.47Å; T233-K236 PolarHBondContact O-N 3.37Å; T233-V237 HydrophobicContact CG2-CG2 4.33Å; T233-V237 VanDerWaalsContact O-CG2 3.3Å; T233-V237 WeakPolarHBondContact O-CG2 3.38Å; T233-V237 PolarHBondContact O-N 3.08Å
234	E	91	Very high	92.1	Very high	87 Å²	87	58 Å²	58	41%	0.407	31%	0.307	S	S	.	.	H	α-helix	trans	-59.5	-50.3	177.7	-63.2	172.3	161.1	0	0	112	C232 K236 V237 F238 N288 M424	C232-E234 PolarHBondContact O-N 3.43Å; E234-K236 VanDerWaalsContact C-N 3.33Å; E234-K236 PolarHBondContact O-N 2.97Å; E234-V237 PolarHBondContact O-N 2.74Å; E234-F238 HydrophobicContact CB-CE2 4.09Å; E234-F238 HydrophobicContact CB-CZ 4.45Å; E234-F238 VanDerWaalsContact O-CD2 3.25Å; E234-F238 WeakPolarHBondContact O-CD2 3.49Å; E234-F238 WeakPolarHBondContact O-CG 3.32Å; E234-F238 PolarHBondContact O-N 2.94Å; E234-N288 PolarHBondContact OE2-ND2 3.37Å; E234-M424 WeakPolarHBondContact OE1-CE 3.48Å; E234-M424 WeakPolarHBondContact OE2-CE 3.43Å
235	N	93.6	Very high	92.3	Very high	0 Å²	0	56.2 Å²	56.2	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-62.2	-42.1	178	-69.4	-3.5	0	0	0	110.9	Y226 T227 C232 V237 F238 I239 M285 N288 C293	Y226-N235 WeakPolarHBondContact O-CB 3.47Å; Y226-N235 PolarHBondContact O-ND2 3.03Å; T227-N235 HydrophobicContact CG2-CB 4.27Å; C232-N235 PolarHBondContact O-N 3.3Å; N235-V237 VanDerWaalsContact C-N 3.32Å; N235-V237 PolarHBondContact O-N 3.48Å; N235-F238 PolarHBondContact O-N 3.27Å; N235-I239 WeakPolarHBondContact O-CD1 3.05Å; N235-I239 WeakPolarHBondContact O-CG1 2.94Å; N235-I239 PolarHBondContact O-N 3.17Å; N235-M285 HydrophobicContact CB-CG 4.43Å; N235-M285 HydrophobicContact CB-SD 3.98Å; N235-N288 PolarHBondContact OD1-ND2 2.87Å; N235-C293 PolarHBondContact ND2-O 3.15Å
236	K	94.2	Very high	92.7	Very high	51 Å²	51	51.5 Å²	51.5	22%	0.222	28%	0.278	C	S	.	.	H	α-helix	trans	-56.9	-46	174.8	-67.5	174.9	-175	163.2	0	111.6	T227 Q228 P229 D231 C232 T233 E234 S240	T227-K236 HydrophobicContact CG2-CG 3.73Å; Q228-K236 WeakPolarHBondContact O-CE 3.35Å; Q228-K236 PolarHBondContact O-NZ 3.11Å; P229-K236 PolarHBondContact O-NZ 2.88Å; D231-K236 VanDerWaalsContact O-CE 3.26Å; D231-K236 WeakPolarHBondContact O-CE 3.33Å; D231-K236 PolarHBondContact O-NZ 3.41Å; C232-K236 PolarHBondContact O-N 3.41Å; C232-K236 VanDerWaalsContact O-N 3.12Å; T233-K236 WeakPolarHBondContact O-CB 3.47Å; T233-K236 PolarHBondContact O-N 3.37Å; E234-K236 VanDerWaalsContact C-N 3.33Å; E234-K236 PolarHBondContact O-N 2.97Å; K236-S240 VanDerWaalsContact O-CB 3.3Å; K236-S240 WeakPolarHBondContact O-CB 3.49Å; K236-S240 PolarHBondContact O-N 3.37Å; K236-S240 PolarHBondContact O-OG 3.35Å
237	V	95.1	Very high	93	Very high	67 Å²	67	55.6 Å²	55.6	41%	0.406	30%	0.301	S	S	.	.	H	α-helix	trans	-64.6	-45.8	179.5	169.3	0	0	0	0	110.6	T233 E234 N235 S240 L241	T233-V237 HydrophobicContact CG2-CG2 4.33Å; T233-V237 VanDerWaalsContact O-CG2 3.3Å; T233-V237 WeakPolarHBondContact O-CG2 3.38Å; T233-V237 PolarHBondContact O-N 3.08Å; E234-V237 PolarHBondContact O-N 2.74Å; N235-V237 VanDerWaalsContact C-N 3.32Å; N235-V237 PolarHBondContact O-N 3.48Å; V237-S240 PolarHBondContact O-N 3.45Å; V237-L241 HydrophobicContact CG1-CD1 3.6Å; V237-L241 HydrophobicContact CG1-CG 4.21Å; V237-L241 WeakPolarHBondContact O-CB 3.46Å; V237-L241 WeakPolarHBondContact O-CG 3.39Å; V237-L241 PolarHBondContact O-N 2.8Å
238	F	95.5	Very high	93.2	Very high	5 Å²	5	58.2 Å²	58.2	2%	0.022	31%	0.313	C	S	.	.	H	α-helix	trans	-60.5	-47.3	178.8	-64.2	-28.5	0	0	0	112.8	E234 N235 N242 V427 W428 M431 W435	E234-F238 HydrophobicContact CB-CE2 4.09Å; E234-F238 HydrophobicContact CB-CZ 4.45Å; E234-F238 VanDerWaalsContact O-CD2 3.25Å; E234-F238 WeakPolarHBondContact O-CD2 3.49Å; E234-F238 WeakPolarHBondContact O-CG 3.32Å; E234-F238 PolarHBondContact O-N 2.94Å; N235-F238 PolarHBondContact O-N 3.27Å; F238-N242 WeakPolarHBondContact O-CB 3.4Å; F238-N242 PolarHBondContact O-N 2.93Å; F238-N242 VanDerWaalsContact O-N 3.11Å; F238-V427 HydrophobicContact CD2-CG1 4.41Å; F238-V427 HydrophobicContact CE2-CG1 3.7Å; F238-V427 HydrophobicContact CZ-CG1 4.29Å; F238-W428 HydrophobicContact CE1-CH2 4.04Å; F238-W428 HydrophobicContact CE1-CZ2 4.35Å; F238-W428 HydrophobicContact CE1-CZ3 4.27Å; F238-W428 HydrophobicContact CZ-CH2 4.33Å; F238-W428 HydrophobicContact CZ-CZ2 4.19Å; F238-M431 HydrophobicContact CB-CE 3.57Å; F238-M431 HydrophobicContact CB-SD 4.18Å; F238-M431 HydrophobicContact CD1-CE 3.68Å; F238-M431 HydrophobicContact CD1-CG 4.25Å; F238-M431 HydrophobicContact CD1-SD 4.48Å; F238-M431 HydrophobicContact CD2-CG 4.39Å; F238-M431 HydrophobicContact CE1-CG 4.34Å; F238-M431 HydrophobicContact CE2-CG 4.49Å; F238-M431 HydrophobicContact CG-CE 3.71Å; F238-M431 HydrophobicContact CG-CG 4.28Å; F238-M431 HydrophobicContact CG-SD 4.17Å; F238-M431 HydrophobicContact CZ-CG 4.46Å; F238-W435 HydrophobicContact CD1-CZ2 4.28Å; F238-W435 HydrophobicContact CE1-CH2 4.5Å
239	I	96.5	Very high	93.5	Very high	0 Å²	0	54.2 Å²	54.2	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-62.3	-47.7	177.9	-60.7	158.2	0	0	0	110.1	V219 F222 Y223 T227 N235 N242 L243 T281 M285	V219-I239 HydrophobicContact CG1-CG2 4.05Å; F222-I239 HydrophobicContact CB-CD1 3.53Å; F222-I239 HydrophobicContact CB-CG1 3.84Å; F222-I239 HydrophobicContact CB-CG2 4.35Å; F222-I239 HydrophobicContact CD2-CG1 4.32Å; Y223-I239 HydrophobicContact CD1-CD1 4.43Å; Y223-I239 HydrophobicContact CD2-CG2 3.91Å; Y223-I239 HydrophobicContact CE1-CB 4.46Å; Y223-I239 HydrophobicContact CE1-CG2 4.29Å; Y223-I239 HydrophobicContact CE2-CB 4.38Å; Y223-I239 HydrophobicContact CE2-CG2 3.4Å; Y223-I239 VanDerWaalsContact CE2-CG2 3.4Å; T227-I239 HydrophobicContact CG2-CD1 3.68Å; N235-I239 WeakPolarHBondContact O-CD1 3.05Å; N235-I239 WeakPolarHBondContact O-CG1 2.94Å; N235-I239 PolarHBondContact O-N 3.17Å; I239-N242 PolarHBondContact O-N 2.83Å; I239-L243 WeakPolarHBondContact O-CB 3.47Å; I239-L243 PolarHBondContact O-N 3.22Å; I239-T281 HydrophobicContact CG1-CG2 4.46Å; I239-M285 HydrophobicContact CD1-CE 4.39Å; I239-M285 HydrophobicContact CD1-SD 3.79Å; I239-M285 HydrophobicContact CG1-CE 4.12Å; I239-M285 HydrophobicContact CG1-SD 3.65Å
240	S	96.3	Very high	94	Very high	39 Å²	39	49.5 Å²	49.5	27%	0.273	26%	0.264	S	S	.	.	H	α-helix	trans	-63.8	-46.3	-176.6	-51.9	0	0	0	0	112	Y223 K236 V237 L243 I244	Y223-S240 PolarHBondContact OH-OG 3.4Å; K236-S240 VanDerWaalsContact O-CB 3.3Å; K236-S240 WeakPolarHBondContact O-CB 3.49Å; K236-S240 PolarHBondContact O-N 3.37Å; K236-S240 PolarHBondContact O-OG 3.35Å; V237-S240 PolarHBondContact O-N 3.45Å; S240-L243 PolarHBondContact O-N 3.12Å; S240-I244 VanDerWaalsContact O-CG1 3.28Å; S240-I244 WeakPolarHBondContact O-CG1 3.38Å; S240-I244 PolarHBondContact O-N 3.36Å
241	L	96.6	Very high	94.5	Very high	59 Å²	59	45.7 Å²	45.7	31%	0.309	25%	0.247	S	C	.	.	H	α-helix	trans	-64.4	-45.3	179.7	-74.7	174.2	0	0	0	111.7	V237 L243 I244 F245 W435	V237-L241 HydrophobicContact CG1-CD1 3.6Å; V237-L241 HydrophobicContact CG1-CG 4.21Å; V237-L241 WeakPolarHBondContact O-CB 3.46Å; V237-L241 WeakPolarHBondContact O-CG 3.39Å; V237-L241 PolarHBondContact O-N 2.8Å; L241-L243 VanDerWaalsContact C-N 3.33Å; L241-L243 PolarHBondContact O-N 3.23Å; L241-I244 PolarHBondContact O-N 3.15Å; L241-F245 HydrophobicContact CB-CE2 4.31Å; L241-F245 WeakPolarHBondContact O-CD2 3.4Å; L241-F245 VanDerWaalsContact O-CG 3.28Å; L241-F245 WeakPolarHBondContact O-CG 3.34Å; L241-F245 PolarHBondContact O-N 3.37Å; L241-W435 HydrophobicContact CD1-CZ2 4.13Å
242	N	96.8	Very high	94.7	Very high	0 Å²	0	44 Å²	44	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-66.8	-36.1	179.4	-77.5	-8.4	0	0	0	112.1	F238 I239 F245 C246 T277 M278 T281 M431 W435	F238-N242 WeakPolarHBondContact O-CB 3.4Å; F238-N242 PolarHBondContact O-N 2.93Å; F238-N242 VanDerWaalsContact O-N 3.11Å; I239-N242 PolarHBondContact O-N 2.83Å; N242-F245 PolarHBondContact O-N 2.81Å; N242-C246 WeakPolarHBondContact O-CB 3.39Å; N242-C246 PolarHBondContact O-N 3.18Å; N242-C246 PolarHBondContact O-SG 3.22Å; N242-T277 HydrophobicContact CB-CG2 3.84Å; N242-M278 HydrophobicContact CB-CE 4.15Å; N242-T281 PolarHBondContact ND2-OG1 3.22Å; N242-M431 VanDerWaalsContact ND2-CE 3.26Å; N242-M431 WeakPolarHBondContact ND2-CE 3.47Å; N242-W435 PolarHBondContact OD1-NE1 3.43Å
243	L	96.4	Very high	94.7	Very high	54 Å²	54	43.7 Å²	43.7	28%	0.283	24%	0.236	S	C	.	.	H	α-helix	trans	-59.7	-47.9	170.7	175.8	62.6	0	0	0	111.3	V219 I239 S240 L241 F245 C246 L247	V219-L243 HydrophobicContact CG1-CD2 4.27Å; V219-L243 HydrophobicContact CG2-CD1 4.35Å; I239-L243 WeakPolarHBondContact O-CB 3.47Å; I239-L243 PolarHBondContact O-N 3.22Å; S240-L243 PolarHBondContact O-N 3.12Å; L241-L243 VanDerWaalsContact C-N 3.33Å; L241-L243 PolarHBondContact O-N 3.23Å; L243-F245 VanDerWaalsContact C-N 3.34Å; L243-F245 PolarHBondContact O-N 3.07Å; L243-C246 PolarHBondContact O-N 3.02Å; L243-L247 HydrophobicContact CD1-CD1 4.39Å; L243-L247 HydrophobicContact CD1-CG 4.33Å; L243-L247 HydrophobicContact CG-CD1 4.3Å; L243-L247 WeakPolarHBondContact O-CG 3.38Å; L243-L247 PolarHBondContact O-N 3.05Å
244	I	96.9	Very high	94.7	Very high	85 Å²	85	43.6 Å²	43.6	44%	0.436	23%	0.232	S	C	.	.	H	α-helix	trans	-59.1	-46.5	178	-69.8	164.7	0	0	0	110.5	S240 L241 C246 L247 I248	S240-I244 VanDerWaalsContact O-CG1 3.28Å; S240-I244 WeakPolarHBondContact O-CG1 3.38Å; S240-I244 PolarHBondContact O-N 3.36Å; L241-I244 PolarHBondContact O-N 3.15Å; I244-C246 PolarHBondContact O-N 3.36Å; I244-L247 PolarHBondContact O-N 2.97Å; I244-I248 HydrophobicContact CG2-CD1 3.77Å; I244-I248 HydrophobicContact CG2-CG1 4.42Å; I244-I248 WeakPolarHBondContact O-CG1 3.45Å; I244-I248 PolarHBondContact O-N 2.93Å
245	F	96.4	Very high	94.7	Very high	67 Å²	67	43.1 Å²	43.1	29%	0.294	23%	0.231	S	C	.	.	H	α-helix	trans	-62.6	-42.9	177.8	-61.8	-29.7	0	0	0	112.3	L241 N242 L243 L247 I248 I249 W435 L438	L241-F245 HydrophobicContact CB-CE2 4.31Å; L241-F245 WeakPolarHBondContact O-CD2 3.4Å; L241-F245 VanDerWaalsContact O-CG 3.28Å; L241-F245 WeakPolarHBondContact O-CG 3.34Å; L241-F245 PolarHBondContact O-N 3.37Å; N242-F245 PolarHBondContact O-N 2.81Å; L243-F245 VanDerWaalsContact C-N 3.34Å; L243-F245 PolarHBondContact O-N 3.07Å; F245-L247 VanDerWaalsContact C-N 3.32Å; F245-L247 PolarHBondContact O-N 3.29Å; F245-I248 PolarHBondContact O-N 3.25Å; F245-I249 WeakPolarHBondContact O-CG1 3.39Å; F245-I249 PolarHBondContact O-N 2.89Å; F245-W435 AromaticContact CD2-CD1 3.79Å; F245-W435 AromaticContact CE2-CD1 3.53Å; F245-W435 HydrophobicContact CE2-CD2 4.49Å; F245-W435 HydrophobicContact CE2-CG 4.04Å; F245-W435 AromaticContact CE2-NE1 3.69Å; F245-L438 HydrophobicContact CB-CD1 3.8Å; F245-L438 HydrophobicContact CD2-CD1 4.09Å; F245-L438 HydrophobicContact CG-CD1 4.4Å
246	C	96.3	Very high	94.5	Very high	8 Å²	8	47.3 Å²	47.3	5%	0.054	26%	0.258	C	S	.	.	H	α-helix	trans	-59.3	-40.3	174.6	-73.3	0	0	0	0	112.5	N242 L243 I244 I249 S250 M278	N242-C246 WeakPolarHBondContact O-CB 3.39Å; N242-C246 PolarHBondContact O-N 3.18Å; N242-C246 PolarHBondContact O-SG 3.22Å; L243-C246 PolarHBondContact O-N 3.02Å; I244-C246 PolarHBondContact O-N 3.36Å; C246-I249 WeakPolarHBondContact O-CG1 3.42Å; C246-S250 WeakPolarHBondContact O-CB 3.45Å; C246-S250 PolarHBondContact O-N 3.41Å; C246-S250 VanDerWaalsContact O-N 3.13Å; C246-S250 PolarHBondContact O-OG 2.97Å; C246-M278 HydrophobicContact CB-CE 4.49Å; C246-M278 VanDerWaalsContact SG-CE 3.53Å
247	L	95.8	Very high	94.2	Very high	103 Å²	103	51 Å²	51	54%	0.539	27%	0.274	S	S	.	.	H	α-helix	trans	-66	-45.2	175.1	-68.5	174.2	0	0	0	111.5	L243 I244 F245 S250 V251	L243-L247 HydrophobicContact CD1-CD1 4.39Å; L243-L247 HydrophobicContact CD1-CG 4.33Å; L243-L247 HydrophobicContact CG-CD1 4.3Å; L243-L247 WeakPolarHBondContact O-CG 3.38Å; L243-L247 PolarHBondContact O-N 3.05Å; I244-L247 PolarHBondContact O-N 2.97Å; F245-L247 VanDerWaalsContact C-N 3.32Å; F245-L247 PolarHBondContact O-N 3.29Å; L247-S250 PolarHBondContact O-N 3.15Å; L247-V251 WeakPolarHBondContact O-CG2 3.48Å; L247-V251 PolarHBondContact O-N 3.22Å
248	I	95.5	Very high	93.9	Very high	79 Å²	79	48 Å²	48	41%	0.405	26%	0.256	S	S	.	.	H	α-helix	trans	-58.7	-52.1	177.9	-69.6	166.8	0	0	0	110.4	I244 F245 S250 V251 V252	I244-I248 HydrophobicContact CG2-CD1 3.77Å; I244-I248 HydrophobicContact CG2-CG1 4.42Å; I244-I248 WeakPolarHBondContact O-CG1 3.45Å; I244-I248 PolarHBondContact O-N 2.93Å; F245-I248 PolarHBondContact O-N 3.25Å; I248-S250 PolarHBondContact O-N 2.97Å; I248-V251 PolarHBondContact O-N 3.25Å; I248-V252 HydrophobicContact CG2-CG2 4.15Å; I248-V252 WeakPolarHBondContact O-CB 3.43Å; I248-V252 WeakPolarHBondContact O-CG2 3.5Å; I248-V252 PolarHBondContact O-N 2.89Å
249	I	93.8	Very high	93.4	Very high	4 Å²	4	51.7 Å²	51.7	2%	0.021	27%	0.273	C	S	.	.	H	α-helix	trans	-61.1	-36.8	-179.4	62.6	166.1	0	0	0	111.5	F245 C246 V252 S253 I273 L438 Y441	F245-I249 WeakPolarHBondContact O-CG1 3.39Å; F245-I249 PolarHBondContact O-N 2.89Å; C246-I249 WeakPolarHBondContact O-CG1 3.42Å; I249-V252 PolarHBondContact O-N 2.8Å; I249-S253 WeakPolarHBondContact O-CB 3.21Å; I249-S253 PolarHBondContact O-N 2.77Å; I249-S253 PolarHBondContact O-OG 3.29Å; I249-I273 HydrophobicContact CD1-CB 4.41Å; I249-I273 HydrophobicContact CD1-CG2 4.08Å; I249-L438 HydrophobicContact CD1-CD2 3.7Å; I249-L438 HydrophobicContact CG2-CD2 4.4Å; I249-Y441 HydrophobicContact CB-CD1 4.1Å; I249-Y441 HydrophobicContact CB-CE1 4.11Å; I249-Y441 HydrophobicContact CD1-CD1 3.98Å; I249-Y441 HydrophobicContact CD1-CE1 4.07Å; I249-Y441 HydrophobicContact CG2-CD1 4.19Å
250	S	94.2	Very high	92.8	Very high	15 Å²	15	57.9 Å²	57.9	11%	0.105	30%	0.302	C	S	.	.	H	α-helix	trans	-67.1	-41.6	179.9	-57.9	0	0	0	0	111.8	Y212 C246 L247 I248	Y212-S250 VanDerWaalsContact OH-CB 3.26Å; Y212-S250 WeakPolarHBondContact OH-CB 3.45Å; Y212-S250 PolarHBondContact OH-OG 3.48Å; C246-S250 WeakPolarHBondContact O-CB 3.45Å; C246-S250 PolarHBondContact O-N 3.41Å; C246-S250 VanDerWaalsContact O-N 3.13Å; C246-S250 PolarHBondContact O-OG 2.97Å; L247-S250 PolarHBondContact O-N 3.15Å; I248-S250 PolarHBondContact O-N 2.97Å
251	V	93.9	Very high	92.1	Very high	85 Å²	85	58.1 Å²	58.1	52%	0.515	31%	0.306	S	S	.	.	H	α-helix	trans	-65.3	-44.3	174	171.8	0	0	0	0	110.5	L247 I248 S253 I254 L255	L247-V251 WeakPolarHBondContact O-CG2 3.48Å; L247-V251 PolarHBondContact O-N 3.22Å; I248-V251 PolarHBondContact O-N 3.25Å; V251-S253 VanDerWaalsContact C-N 3.35Å; V251-S253 PolarHBondContact O-N 3.45Å; V251-I254 WeakPolarHBondContact O-CG1 2.88Å; V251-I254 PolarHBondContact O-N 3.42Å; V251-L255 PolarHBondContact O-N 3.25Å
252	V	92.8	Very high	91.3	Very high	20 Å²	20	57.2 Å²	57.2	12%	0.121	30%	0.301	C	S	.	.	H	α-helix	trans	-62.3	-42.4	-179.5	172.9	0	0	0	0	111	I248 I249 I254 L255 I258 L442 L445 I446	I248-V252 HydrophobicContact CG2-CG2 4.15Å; I248-V252 WeakPolarHBondContact O-CB 3.43Å; I248-V252 WeakPolarHBondContact O-CG2 3.5Å; I248-V252 PolarHBondContact O-N 2.89Å; I249-V252 PolarHBondContact O-N 2.8Å; V252-I254 PolarHBondContact O-N 3.05Å; V252-I254 VanDerWaalsContact O-N 3.1Å; V252-L255 HydrophobicContact CB-CD1 4.46Å; V252-L255 HydrophobicContact CG2-CD1 4.34Å; V252-L255 PolarHBondContact O-N 3.49Å; V252-L255 VanDerWaalsContact O-N 3.17Å; V252-I258 HydrophobicContact CB-CD1 4.34Å; V252-I258 HydrophobicContact CG1-CD1 3.18Å; V252-I258 WeakPolarHBondContact O-CD1 3.48Å; V252-L442 HydrophobicContact CB-CD1 4.14Å; V252-L442 HydrophobicContact CG1-CD1 3.72Å; V252-L442 HydrophobicContact CG2-CD1 4.08Å; V252-L445 HydrophobicContact CG1-CD1 4.25Å; V252-I446 HydrophobicContact CG1-CG1 4.38Å
253	S	90.4	Very high	90.2	Very high	0 Å²	0	61.9 Å²	61.9	0%	0	33%	0.331	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61.8	-17.9	178.6	-62.8	0	0	0	0	115.3	I249 V251 Y441 L445	I249-S253 WeakPolarHBondContact O-CB 3.21Å; I249-S253 PolarHBondContact O-N 2.77Å; I249-S253 PolarHBondContact O-OG 3.29Å; V251-S253 VanDerWaalsContact C-N 3.35Å; V251-S253 PolarHBondContact O-N 3.45Å; S253-Y441 PolarHBondContact OG-OH 2.86Å; S253-L445 VanDerWaalsContact OG-CD1 3.3Å; S253-L445 WeakPolarHBondContact OG-CD1 3.36Å
254	I	90.8	Very high	89	Confident	88 Å²	88	62 Å²	62	45%	0.451	33%	0.33	S	S	.	.	T	Hydrogen-bonded Turn	trans	-107.4	0.2	179.4	64.8	166.8	0	0	0	113.6	V251 V252 L267	V251-I254 WeakPolarHBondContact O-CG1 2.88Å; V251-I254 PolarHBondContact O-N 3.42Å; V252-I254 PolarHBondContact O-N 3.05Å; V252-I254 VanDerWaalsContact O-N 3.1Å; I254-L267 HydrophobicContact CG2-CD1 4.07Å
255	L	90.9	Very high	88	Confident	76 Å²	76	58.3 Å²	58.3	40%	0.398	31%	0.311	S	S	.	.			trans	-63.3	130.4	178.4	-76.5	167.2	0	0	0	109.7	V251 V252 K257 I258 Q259	V251-L255 PolarHBondContact O-N 3.25Å; V252-L255 HydrophobicContact CB-CD1 4.46Å; V252-L255 HydrophobicContact CG2-CD1 4.34Å; V252-L255 PolarHBondContact O-N 3.49Å; V252-L255 VanDerWaalsContact O-N 3.17Å; L255-K257 PolarHBondContact O-N 3.47Å; L255-K257 VanDerWaalsContact O-N 3.13Å; L255-I258 HydrophobicContact CB-CB 4.44Å; L255-I258 HydrophobicContact CB-CD1 4.32Å; L255-I258 HydrophobicContact CB-CG1 4.43Å; L255-I258 HydrophobicContact CD1-CD1 4.21Å; L255-I258 PolarHBondContact O-N 3.02Å; L255-Q259 PolarHBondContact O-N 3.18Å; L255-Q259 VanDerWaalsContact O-N 3.12Å
256	P	88.8	Confident	87.3	Confident	88 Å²	88	55.5 Å²	55.5	57%	0.571	30%	0.302	S	S	*	.	H	α-helix	trans	-54.5	-38.4	-178.1	-27.9	34.1	0	0	0	112.9	I258 Q259 E260	P256-I258 VanDerWaalsContact C-N 3.32Å; P256-I258 PolarHBondContact O-N 3.06Å; P256-Q259 PolarHBondContact O-N 3.33Å; P256-E260 WeakPolarHBondContact O-CG 3.41Å; P256-E260 PolarHBondContact O-N 2.78Å
257	K	88.3	Confident	87	Confident	129 Å²	129	58.4 Å²	58.4	56%	0.561	32%	0.316	S	S	*	.	H	α-helix	trans	-61.4	-37.9	177	-69.6	-65.5	170.2	-158.6	0	113.4	L255 E260 A261 L449	L255-K257 PolarHBondContact O-N 3.47Å; L255-K257 VanDerWaalsContact O-N 3.13Å; K257-E260 WeakPolarHBondContact CD-OE2 3.44Å; K257-E260 IonicContact NZ-OE1 2.96Å; K257-E260 IonicContact NZ-OE2 3.17Å; K257-E260 PolarHBondContact NZ-OE2 2.85Å; K257-A261 PolarHBondContact O-N 2.94Å; K257-L449 HydrophobicContact CB-CD1 4.39Å; K257-L449 WeakPolarHBondContact O-CD2 3.46Å
258	I	88.3	Confident	86.8	Confident	5 Å²	5	53.7 Å²	53.7	3%	0.026	29%	0.292	C	S	.	.	H	α-helix	trans	-73.4	-38.7	178.3	-72.4	173.6	0	0	0	110.6	V252 L255 P256 E260 A261 Q262 L445 I446 L449	V252-I258 HydrophobicContact CB-CD1 4.34Å; V252-I258 HydrophobicContact CG1-CD1 3.18Å; V252-I258 WeakPolarHBondContact O-CD1 3.48Å; L255-I258 HydrophobicContact CB-CB 4.44Å; L255-I258 HydrophobicContact CB-CD1 4.32Å; L255-I258 HydrophobicContact CB-CG1 4.43Å; L255-I258 HydrophobicContact CD1-CD1 4.21Å; L255-I258 PolarHBondContact O-N 3.02Å; P256-I258 VanDerWaalsContact C-N 3.32Å; P256-I258 PolarHBondContact O-N 3.06Å; I258-E260 VanDerWaalsContact C-N 3.33Å; I258-E260 PolarHBondContact O-N 2.77Å; I258-A261 PolarHBondContact O-N 3.27Å; I258-Q262 PolarHBondContact O-N 3.2Å; I258-L445 HydrophobicContact CG2-CB 4.22Å; I258-L445 HydrophobicContact CG2-CD2 4.44Å; I258-I446 HydrophobicContact CD1-CG1 4.46Å; I258-L449 HydrophobicContact CB-CD1 4.42Å; I258-L449 HydrophobicContact CD1-CD1 4.41Å; I258-L449 HydrophobicContact CG1-CD1 3.41Å; I258-L449 VanDerWaalsContact CG1-CD1 3.41Å
259	Q	85.7	Confident	86.6	Confident	81 Å²	81	49.9 Å²	49.9	38%	0.379	27%	0.272	S	S	.	.	H	α-helix	trans	-67.9	-32.6	175.9	-66.6	-178.2	-18.5	0	0	112.5	L255 P256 Q262 P263	L255-Q259 PolarHBondContact O-N 3.18Å; L255-Q259 VanDerWaalsContact O-N 3.12Å; P256-Q259 PolarHBondContact O-N 3.33Å; Q259-Q262 CarbonylContact O-C 3.28Å; Q259-Q262 VanDerWaalsContact O-C 3.28Å; Q259-P263 VanDerWaalsContact O-CA 3.23Å; Q259-P263 WeakPolarHBondContact O-CA 3.26Å
260	E	85.3	Confident	86.6	Confident	131 Å²	131	49.7 Å²	49.7	61%	0.612	27%	0.271	S	S	*	.	H	α-helix	trans	-61.8	-41.6	171.5	-77	168.4	-158.7	0	0	111.7	P256 K257 I258	P256-E260 WeakPolarHBondContact O-CG 3.41Å; P256-E260 PolarHBondContact O-N 2.78Å; K257-E260 WeakPolarHBondContact CD-OE2 3.44Å; K257-E260 IonicContact NZ-OE1 2.96Å; K257-E260 IonicContact NZ-OE2 3.17Å; K257-E260 PolarHBondContact NZ-OE2 2.85Å; I258-E260 VanDerWaalsContact C-N 3.33Å; I258-E260 PolarHBondContact O-N 2.77Å
261	A	81.5	Confident	86.6	Confident	43 Å²	43	49 Å²	49	36%	0.355	27%	0.266	S	S	.	.	H	α-helix	trans	-82.5	-27.7	179.9	0	0	0	0	0	113.7	K257 I258 P448 L449	K257-A261 PolarHBondContact O-N 2.94Å; I258-A261 PolarHBondContact O-N 3.27Å; A261-P448 HydrophobicContact CB-CB 4.2Å; A261-L449 HydrophobicContact CB-CD2 3.55Å; A261-L449 HydrophobicContact CB-CG 3.86Å
262	Q	77.8	Confident	86.7	Confident	41 Å²	41	46.4 Å²	46.4	19%	0.192	25%	0.249	C	C	.	.			trans	-139.1	87.1	178.9	-165.5	-172.3	-15.4	0	0	109.7	H182 I258 Q259 H264 S265	H182-Q262 PolarHBondContact CE1-NE2 3.48Å; H182-Q262 PolarHBondContact ND1-NE2 3.26Å; I258-Q262 PolarHBondContact O-N 3.2Å; Q259-Q262 CarbonylContact O-C 3.28Å; Q259-Q262 VanDerWaalsContact O-C 3.28Å; Q262-H264 PolarHBondContact O-N 2.96Å; Q262-H264 VanDerWaalsContact O-N 3.13Å; Q262-S265 WeakPolarHBondContact CB-OG 3.42Å; Q262-S265 WeakPolarHBondContact CG-OG 3.3Å; Q262-S265 PolarHBondContact NE2-OG 3.1Å; Q262-S265 VanDerWaalsContact O-CB 3.24Å; Q262-S265 WeakPolarHBondContact O-CB 3.43Å; Q262-S265 PolarHBondContact O-N 3.5Å; Q262-S265 PolarHBondContact O-OG 3.32Å; Q262-S265 PolarHBondContact OE1-OG 3.35Å
263	P	73.7	Confident	86.8	Confident	97 Å²	97	45.5 Å²	45.5	63%	0.63	24%	0.244	S	C	*	.	T	Hydrogen-bonded Turn	trans	-64.5	-22	-173.4	21.8	-31.8	0	0	0	113.7	Q259 S265	Q259-P263 VanDerWaalsContact O-CA 3.23Å; Q259-P263 WeakPolarHBondContact O-CA 3.26Å; P263-S265 VanDerWaalsContact C-N 3.33Å
264	H	72.8	Confident	87	Confident	58 Å²	58	45.6 Å²	45.6	27%	0.269	24%	0.244	S	C	.	.	T	Hydrogen-bonded Turn	trans	-90	8.8	175	-52.6	-64.7	0	0	0	113.6	N185 K186 Q262 Q269	N185-H264 PolarHBondContact ND2-O 3.29Å; K186-H264 HydrophobicContact CB-CB 4.46Å; Q262-H264 PolarHBondContact O-N 2.96Å; Q262-H264 VanDerWaalsContact O-N 3.13Å; H264-Q269 PolarHBondContact O-NE2 2.91Å
265	S	75	Confident	87.3	Confident	6 Å²	6	43.5 Å²	43.5	4%	0.042	23%	0.234	C	C	.	.			trans	-72.9	127.9	168.2	-77.4	0	0	0	0	109.9	Q262 P263 L445	Q262-S265 WeakPolarHBondContact CB-OG 3.42Å; Q262-S265 WeakPolarHBondContact CG-OG 3.3Å; Q262-S265 PolarHBondContact NE2-OG 3.1Å; Q262-S265 VanDerWaalsContact O-CB 3.24Å; Q262-S265 WeakPolarHBondContact O-CB 3.43Å; Q262-S265 PolarHBondContact O-N 3.5Å; Q262-S265 PolarHBondContact O-OG 3.32Å; Q262-S265 PolarHBondContact OE1-OG 3.35Å; P263-S265 VanDerWaalsContact C-N 3.33Å; S265-L445 WeakPolarHBondContact OG-CD2 3.28Å
266	G	82.1	Confident	87.5	Confident	9 Å²	9	40.7 Å²	40.7	9%	0.093	22%	0.218	C	C	.	.			trans	-145.5	159	-172.2	0	0	0	0	0	113.6	L268 Q269	G266-L268 PolarHBondContact O-N 3.23Å; G266-Q269 VanDerWaalsContact N-OE1 3.15Å; G266-Q269 PolarHBondContact O-N 2.81Å
267	L	89.8	Confident	87.9	Confident	68 Å²	68	36.6 Å²	36.6	36%	0.356	19%	0.191	S	C	.	.	H	α-helix	trans	-65.1	-25.3	179.6	-168.9	66.6	0	0	0	112.4	T208 Y212 I254 Q269 A270 S271	T208-L267 HydrophobicContact CG2-CB 4.02Å; T208-L267 HydrophobicContact CG2-CD2 3.67Å; T208-L267 HydrophobicContact CG2-CG 3.6Å; Y212-L267 HydrophobicContact CE2-CD1 3.78Å; Y212-L267 HydrophobicContact CE2-CD2 4.09Å; Y212-L267 HydrophobicContact CE2-CG 3.73Å; Y212-L267 VanDerWaalsContact OH-CD1 3.23Å; Y212-L267 WeakPolarHBondContact OH-CD1 3.22Å; I254-L267 HydrophobicContact CG2-CD1 4.07Å; L267-Q269 VanDerWaalsContact C-N 3.32Å; L267-Q269 PolarHBondContact O-N 3.49Å; L267-A270 PolarHBondContact O-N 3.12Å; L267-S271 WeakPolarHBondContact O-CB 3.32Å; L267-S271 PolarHBondContact O-N 2.83Å; L267-S271 PolarHBondContact O-OG 2.62Å
268	L	90.9	Very high	88.3	Confident	4 Å²	4	30.7 Å²	30.7	2%	0.021	17%	0.166	C	C	.	.	H	α-helix	trans	-57.1	-45.5	174.5	-178.9	68.7	0	0	0	111.4	W184 N185 L204 F207 T208 G266 S271 L272	W184-L268 HydrophobicContact CD2-CD2 4.41Å; W184-L268 HydrophobicContact CG-CD2 4.28Å; N185-L268 HydrophobicContact CB-CD2 4.37Å; L204-L268 HydrophobicContact CD1-CD2 4.06Å; L204-L268 HydrophobicContact CG-CB 4.37Å; L204-L268 HydrophobicContact CG-CD2 4.19Å; F207-L268 HydrophobicContact CB-CD1 3.72Å; T208-L268 WeakPolarHBondContact OG1-CA 3.5Å; G266-L268 PolarHBondContact O-N 3.23Å; L268-S271 PolarHBondContact O-N 2.97Å; L268-S271 PolarHBondContact O-OG 2.73Å; L268-L272 PolarHBondContact O-N 3.01Å; L268-L272 VanDerWaalsContact O-N 3.11Å
269	Q	91.4	Very high	88.6	Confident	0 Å²	0	31.7 Å²	31.7	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-62.2	-51.8	179.6	-65.3	151.2	0.9	0	0	110.7	A181 H182 N185 H264 G266 L267 S271 L272 I273 Y441	A181-Q269 HydrophobicContact CB-CB 4.12Å; A181-Q269 HydrophobicContact CB-CG 3.93Å; A181-Q269 WeakPolarHBondContact O-CG 3.37Å; H182-Q269 VanDerWaalsContact CE1-CD 3.46Å; H182-Q269 PolarHBondContact CE1-OE1 2.94Å; H182-Q269 PolarHBondContact ND1-NE2 2.72Å; H182-Q269 PolarHBondContact ND1-OE1 3.21Å; N185-Q269 HydrophobicContact CB-CG 4.09Å; N185-Q269 VanDerWaalsContact CB-NE2 3.26Å; N185-Q269 PolarHBondContact ND2-NE2 2.93Å; H264-Q269 PolarHBondContact O-NE2 2.91Å; G266-Q269 VanDerWaalsContact N-OE1 3.15Å; G266-Q269 PolarHBondContact O-N 2.81Å; L267-Q269 VanDerWaalsContact C-N 3.32Å; L267-Q269 PolarHBondContact O-N 3.49Å; Q269-S271 VanDerWaalsContact C-N 3.26Å; Q269-S271 PolarHBondContact O-N 3.3Å; Q269-L272 PolarHBondContact O-N 3.01Å; Q269-I273 WeakPolarHBondContact O-CG1 3.47Å; Q269-I273 PolarHBondContact O-N 2.72Å; Q269-Y441 HydrophobicContact CB-CE2 4.35Å; Q269-Y441 WeakPolarHBondContact CB-OH 3.44Å
270	A	93.8	Very high	89.1	Confident	0 Å²	0	28.1 Å²	28.1	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-59.7	-37.1	179.3	0	0	0	0	0	112.4	L267 S274 Y441	L267-A270 PolarHBondContact O-N 3.12Å; A270-S274 VanDerWaalsContact O-CB 3.3Å; A270-S274 WeakPolarHBondContact O-CB 3.18Å; A270-S274 PolarHBondContact O-N 3.26Å; A270-S274 PolarHBondContact O-OG 2.96Å; A270-Y441 HydrophobicContact CB-CE1 4.36Å; A270-Y441 PolarHBondContact N-OH 3.39Å
271	S	95.8	Very high	89.6	Confident	0 Å²	0	21.9 Å²	21.9	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-65.4	-43.4	177.8	78.3	0	0	0	0	112.6	H211 Y212 L267 L268 Q269 S274 L275	H211-S271 PolarHBondContact ND1-OG 3.3Å; Y212-S271 VanDerWaalsContact CE2-CB 3.42Å; Y212-S271 PolarHBondContact OH-N 3.33Å; L267-S271 WeakPolarHBondContact O-CB 3.32Å; L267-S271 PolarHBondContact O-N 2.83Å; L267-S271 PolarHBondContact O-OG 2.62Å; L268-S271 PolarHBondContact O-N 2.97Å; L268-S271 PolarHBondContact O-OG 2.73Å; Q269-S271 VanDerWaalsContact C-N 3.26Å; Q269-S271 PolarHBondContact O-N 3.3Å; S271-S274 PolarHBondContact O-N 3.42Å; S271-L275 PolarHBondContact O-N 3.2Å
272	L	95.2	Very high	90.1	Very high	30 Å²	30	22.2 Å²	22.2	16%	0.157	12%	0.116	C	C	.	.	H	α-helix	trans	-68.5	-43.1	179.2	-177.6	64.2	0	0	0	111.3	F180 A181 L268 Q269 S274 L275 Y276	F180-L272 HydrophobicContact CD1-CD2 4.02Å; F180-L272 HydrophobicContact CE1-CD2 4.1Å; A181-L272 HydrophobicContact CB-CD2 3.96Å; L268-L272 PolarHBondContact O-N 3.01Å; L268-L272 VanDerWaalsContact O-N 3.11Å; Q269-L272 PolarHBondContact O-N 3.01Å; L272-S274 VanDerWaalsContact C-N 3.32Å; L272-S274 PolarHBondContact O-N 3.03Å; L272-L275 PolarHBondContact O-N 2.91Å; L272-Y276 PolarHBondContact O-N 3.11Å
273	I	94.3	Very high	90.8	Very high	1 Å²	1	20.7 Å²	20.7	1%	0.005	11%	0.11	C	C	.	.	H	α-helix	trans	-63.1	-41.3	175.9	-61.2	-51.8	0	0	0	110.6	L174 I178 I249 Q269 L275 Y276 T277 L438 Y441	L174-I273 HydrophobicContact CD1-CD1 4.02Å; I178-I273 HydrophobicContact CB-CD1 4.41Å; I178-I273 HydrophobicContact CG1-CD1 3.56Å; I178-I273 HydrophobicContact CG1-CG1 4.2Å; I249-I273 HydrophobicContact CD1-CB 4.41Å; I249-I273 HydrophobicContact CD1-CG2 4.08Å; Q269-I273 WeakPolarHBondContact O-CG1 3.47Å; Q269-I273 PolarHBondContact O-N 2.72Å; I273-L275 PolarHBondContact O-N 3.36Å; I273-Y276 PolarHBondContact O-N 3.14Å; I273-T277 PolarHBondContact O-N 3.43Å; I273-T277 PolarHBondContact O-OG1 2.81Å; I273-T277 VanDerWaalsContact O-OG1 3.06Å; I273-L438 HydrophobicContact CG2-CD2 4Å; I273-Y441 HydrophobicContact CG1-CD2 4.25Å; I273-Y441 HydrophobicContact CG1-CE2 4.36Å; I273-Y441 HydrophobicContact CG1-CG 4.35Å; I273-Y441 HydrophobicContact CG2-CD1 4.3Å; I273-Y441 HydrophobicContact CG2-CG 4.41Å
274	S	95.9	Very high	91.8	Very high	2 Å²	2	16.1 Å²	16.1	1%	0.014	8%	0.08	C	C	.	.	H	α-helix	trans	-61.6	-42.4	175.7	-61.4	0	0	0	0	112.3	A270 S271 L272 T277 M278	A270-S274 VanDerWaalsContact O-CB 3.3Å; A270-S274 WeakPolarHBondContact O-CB 3.18Å; A270-S274 PolarHBondContact O-N 3.26Å; A270-S274 PolarHBondContact O-OG 2.96Å; S271-S274 PolarHBondContact O-N 3.42Å; L272-S274 VanDerWaalsContact C-N 3.32Å; L272-S274 PolarHBondContact O-N 3.03Å; S274-T277 WeakPolarHBondContact O-CB 3.41Å; S274-T277 PolarHBondContact O-N 2.85Å; S274-M278 WeakPolarHBondContact O-CG 3.38Å; S274-M278 PolarHBondContact O-N 3.3Å
275	L	96.3	Very high	92.6	Very high	45 Å²	45	13.3 Å²	13.3	24%	0.236	7%	0.067	C	C	.	.	H	α-helix	trans	-62.8	-42.6	175.8	-178	60.5	0	0	0	111.8	H211 L214 A215 S271 L272 I273 M278 Y279	H211-L275 HydrophobicContact CB-CD2 4.37Å; L214-L275 HydrophobicContact CB-CD1 3.79Å; L214-L275 HydrophobicContact CD1-CD2 4.35Å; A215-L275 HydrophobicContact CB-CD1 4.45Å; S271-L275 PolarHBondContact O-N 3.2Å; L272-L275 PolarHBondContact O-N 2.91Å; I273-L275 PolarHBondContact O-N 3.36Å; L275-M278 PolarHBondContact O-N 3.08Å; L275-Y279 PolarHBondContact O-N 3.49Å
276	Y	95.6	Very high	93.3	Very high	16 Å²	16	13.7 Å²	13.7	6%	0.063	7%	0.069	C	C	.	.	H	α-helix	trans	-63.5	-41	174.8	178	-98.9	0	0	0	112.2	Q173 L174 L177 L272 I273 M278 Y279 V280 I333	Q173-Y276 PolarHBondContact OE1-OH 3.35Å; Q173-Y276 VanDerWaalsContact OE1-OH 3.08Å; L174-Y276 HydrophobicContact CB-CE1 4.24Å; L174-Y276 HydrophobicContact CD1-CD1 3.53Å; L174-Y276 HydrophobicContact CD1-CE1 3.64Å; L174-Y276 HydrophobicContact CD1-CG 4.47Å; L174-Y276 HydrophobicContact CG-CE1 4.41Å; L177-Y276 HydrophobicContact CD1-CD1 4.31Å; L177-Y276 HydrophobicContact CD1-CD2 3.42Å; L177-Y276 VanDerWaalsContact CD1-CD2 3.42Å; L177-Y276 HydrophobicContact CD1-CE1 4.4Å; L177-Y276 HydrophobicContact CD1-CE2 3.56Å; L177-Y276 HydrophobicContact CD1-CG 3.81Å; L272-Y276 PolarHBondContact O-N 3.11Å; I273-Y276 PolarHBondContact O-N 3.14Å; Y276-M278 VanDerWaalsContact C-N 3.3Å; Y276-M278 PolarHBondContact O-N 2.86Å; Y276-Y279 HydrophobicContact CD2-CD1 4.01Å; Y276-Y279 AromaticContact CE2-CD1 3.93Å; Y276-Y279 HydrophobicContact CE2-CD1 3.93Å; Y276-Y279 HydrophobicContact CE2-CE1 4.21Å; Y276-Y279 WeakPolarHBondContact O-CB 3.28Å; Y276-Y279 PolarHBondContact O-N 3.3Å; Y276-Y279 VanDerWaalsContact O-N 3.12Å; Y276-V280 HydrophobicContact CD1-CG2 4.01Å; Y276-V280 HydrophobicContact CE1-CG2 3.49Å; Y276-V280 VanDerWaalsContact CE1-CG2 3.49Å; Y276-V280 HydrophobicContact CE2-CG2 4.05Å; Y276-V280 WeakPolarHBondContact O-CG2 3.38Å; Y276-V280 PolarHBondContact O-N 2.86Å; Y276-I333 HydrophobicContact CD2-CD1 4.19Å; Y276-I333 HydrophobicContact CE2-CD1 4.24Å; Y276-I333 HydrophobicContact CE2-CG2 4.16Å
277	T	96.1	Very high	93.5	Very high	2 Å²	2	13.4 Å²	13.4	1%	0.012	7%	0.066	C	C	.	.	H	α-helix	trans	-57.3	-42.9	172.8	-61.8	0	0	0	0	111.3	N242 I273 S274 Y279 V280 T281 L438	N242-T277 HydrophobicContact CB-CG2 3.84Å; I273-T277 PolarHBondContact O-N 3.43Å; I273-T277 PolarHBondContact O-OG1 2.81Å; I273-T277 VanDerWaalsContact O-OG1 3.06Å; S274-T277 WeakPolarHBondContact O-CB 3.41Å; S274-T277 PolarHBondContact O-N 2.85Å; T277-Y279 VanDerWaalsContact C-N 3.33Å; T277-Y279 PolarHBondContact O-N 3Å; T277-V280 PolarHBondContact O-N 3.14Å; T277-T281 WeakPolarHBondContact O-CB 3.26Å; T277-T281 PolarHBondContact O-N 3.27Å; T277-T281 PolarHBondContact O-OG1 3.33Å; T277-L438 HydrophobicContact CG2-CD1 3.84Å
278	M	96.6	Very high	93.5	Very high	6 Å²	6	10.2 Å²	10.2	3%	0.03	5%	0.049	C	C	.	.	H	α-helix	trans	-62.9	-40.1	175.6	-65.6	-51.7	117.1	0	0	112	A215 A218 V219 F222 N242 C246 S274 L275 Y276 T281 W282	A215-M278 HydrophobicContact CB-CG 3.98Å; A218-M278 HydrophobicContact CB-CB 4.12Å; A218-M278 HydrophobicContact CB-CG 4.45Å; V219-M278 HydrophobicContact CG2-CE 4.42Å; V219-M278 HydrophobicContact CG2-CG 4.44Å; V219-M278 HydrophobicContact CG2-SD 3.4Å; V219-M278 WeakPolarHBondContact CG2-SD 3.2Å; F222-M278 HydrophobicContact CE2-CB 4.11Å; F222-M278 HydrophobicContact CE2-SD 4.07Å; F222-M278 HydrophobicContact CZ-CB 4.37Å; F222-M278 VanDerWaalsContact CZ-O 3.32Å; F222-M278 WeakPolarHBondContact CZ-O 3.34Å; N242-M278 HydrophobicContact CB-CE 4.15Å; C246-M278 HydrophobicContact CB-CE 4.49Å; C246-M278 VanDerWaalsContact SG-CE 3.53Å; S274-M278 WeakPolarHBondContact O-CG 3.38Å; S274-M278 PolarHBondContact O-N 3.3Å; L275-M278 PolarHBondContact O-N 3.08Å; Y276-M278 VanDerWaalsContact C-N 3.3Å; Y276-M278 PolarHBondContact O-N 2.86Å; M278-T281 WeakPolarHBondContact O-CB 3.37Å; M278-T281 PolarHBondContact O-N 2.78Å; M278-W282 PolarHBondContact O-N 3.44Å
279	Y	95.5	Very high	93.3	Very high	26 Å²	26	12.7 Å²	12.7	10%	0.102	7%	0.065	C	C	.	.	H	α-helix	trans	-60.6	-47.9	173.1	160.5	-101.9	0	0	0	112.3	L275 Y276 T277 T281 W282 S283 Q326 V329 G330 I333	L275-Y279 PolarHBondContact O-N 3.49Å; Y276-Y279 HydrophobicContact CD2-CD1 4.01Å; Y276-Y279 AromaticContact CE2-CD1 3.93Å; Y276-Y279 HydrophobicContact CE2-CD1 3.93Å; Y276-Y279 HydrophobicContact CE2-CE1 4.21Å; Y276-Y279 WeakPolarHBondContact O-CB 3.28Å; Y276-Y279 PolarHBondContact O-N 3.3Å; Y276-Y279 VanDerWaalsContact O-N 3.12Å; T277-Y279 VanDerWaalsContact C-N 3.33Å; T277-Y279 PolarHBondContact O-N 3Å; Y279-T281 VanDerWaalsContact C-N 3.3Å; Y279-T281 PolarHBondContact O-N 2.99Å; Y279-W282 HydrophobicContact CD2-CE3 4.32Å; Y279-W282 WeakPolarHBondContact O-CB 3.35Å; Y279-W282 PolarHBondContact O-N 2.97Å; Y279-S283 WeakPolarHBondContact O-CB 3.45Å; Y279-S283 PolarHBondContact O-N 3.24Å; Y279-Q326 WeakPolarHBondContact CE2-O 3.25Å; Y279-Q326 PolarHBondContact OH-O 3.49Å; Y279-V329 HydrophobicContact CD2-CB 4.05Å; Y279-V329 HydrophobicContact CD2-CG1 3.48Å; Y279-V329 VanDerWaalsContact CD2-CG1 3.48Å; Y279-V329 HydrophobicContact CE2-CB 3.76Å; Y279-V329 HydrophobicContact CE2-CG1 3.59Å; Y279-V329 HydrophobicContact CG-CG1 4.22Å; Y279-G330 WeakPolarHBondContact OH-CA 3.33Å; Y279-G330 PolarHBondContact OH-N 3.23Å; Y279-I333 HydrophobicContact CD1-CD1 3.59Å; Y279-I333 HydrophobicContact CD2-CD1 4.45Å; Y279-I333 HydrophobicContact CE1-CD1 3.62Å; Y279-I333 HydrophobicContact CE2-CD1 4.47Å; Y279-I333 HydrophobicContact CG-CD1 4.04Å
280	V	95.1	Very high	92.9	Very high	5 Å²	5	15.3 Å²	15.3	3%	0.03	8%	0.079	C	C	.	.	H	α-helix	trans	-64.1	-38.3	178.6	178.7	0	0	0	0	111	Y276 T277 S283 A284 K430	Y276-V280 HydrophobicContact CD1-CG2 4.01Å; Y276-V280 HydrophobicContact CE1-CG2 3.49Å; Y276-V280 VanDerWaalsContact CE1-CG2 3.49Å; Y276-V280 HydrophobicContact CE2-CG2 4.05Å; Y276-V280 WeakPolarHBondContact O-CG2 3.38Å; Y276-V280 PolarHBondContact O-N 2.86Å; T277-V280 PolarHBondContact O-N 3.14Å; V280-S283 PolarHBondContact O-N 2.96Å; V280-A284 WeakPolarHBondContact O-CB 3.42Å; V280-A284 PolarHBondContact O-N 3.41Å; V280-K430 HydrophobicContact CG1-CB 4.1Å; V280-K430 VanDerWaalsContact CG1-O 3.3Å; V280-K430 WeakPolarHBondContact CG1-O 3.49Å
281	T	95.6	Very high	92.1	Very high	0 Å²	0	22.7 Å²	22.7	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-59.2	-49.1	174.9	-49.7	0	0	0	0	110.9	I239 N242 T277 M278 Y279 A284 M285	I239-T281 HydrophobicContact CG1-CG2 4.46Å; N242-T281 PolarHBondContact ND2-OG1 3.22Å; T277-T281 WeakPolarHBondContact O-CB 3.26Å; T277-T281 PolarHBondContact O-N 3.27Å; T277-T281 PolarHBondContact O-OG1 3.33Å; M278-T281 WeakPolarHBondContact O-CB 3.37Å; M278-T281 PolarHBondContact O-N 2.78Å; Y279-T281 VanDerWaalsContact C-N 3.3Å; Y279-T281 PolarHBondContact O-N 2.99Å; T281-A284 PolarHBondContact O-N 2.99Å; T281-M285 HydrophobicContact CG2-CE 4Å; T281-M285 HydrophobicContact CG2-SD 4.36Å; T281-M285 WeakPolarHBondContact O-CG 3.3Å; T281-M285 PolarHBondContact O-N 2.92Å
282	W	93.8	Very high	91.4	Very high	51 Å²	51	29.6 Å²	29.6	19%	0.193	14%	0.137	C	C	.	.	H	α-helix	trans	-59.1	-50.2	175.7	179.7	39.9	0	0	0	111.7	F222 Y226 M278 Y279 A284 M285 T286 A325 Q326 V329	F222-W282 HydrophobicContact CE1-CB 3.64Å; F222-W282 AromaticContact CE1-CG 3.91Å; F222-W282 HydrophobicContact CE1-CG 3.91Å; F222-W282 HydrophobicContact CZ-CB 3.59Å; F222-W282 HydrophobicContact CZ-CG 4.33Å; Y226-W282 AromaticContact CE2-CD1 3.86Å; Y226-W282 AromaticContact CE2-NE1 3.91Å; Y226-W282 AromaticContact CZ-CD1 3.8Å; Y226-W282 AromaticContact CZ-NE1 3.69Å; Y226-W282 PolarHBondContact OH-NE1 3.31Å; M278-W282 PolarHBondContact O-N 3.44Å; Y279-W282 HydrophobicContact CD2-CE3 4.32Å; Y279-W282 WeakPolarHBondContact O-CB 3.35Å; Y279-W282 PolarHBondContact O-N 2.97Å; W282-A284 PolarHBondContact O-N 3.14Å; W282-M285 PolarHBondContact O-N 3.23Å; W282-M285 VanDerWaalsContact O-N 3.14Å; W282-T286 WeakPolarHBondContact O-CG2 3.33Å; W282-T286 PolarHBondContact O-N 3.35Å; W282-A325 HydrophobicContact CH2-CB 3.74Å; W282-A325 HydrophobicContact CZ2-CB 4.25Å; W282-Q326 HydrophobicContact CD2-CB 4.12Å; W282-Q326 HydrophobicContact CE3-CB 3.82Å; W282-Q326 HydrophobicContact CH2-CB 3.9Å; W282-Q326 HydrophobicContact CZ2-CB 4.15Å; W282-Q326 VanDerWaalsContact CZ3-CA 3.46Å; W282-Q326 HydrophobicContact CZ3-CB 3.72Å; W282-V329 HydrophobicContact CZ3-CG2 4.45Å
283	S	92.6	Very high	90.9	Very high	9 Å²	9	28.2 Å²	28.2	6%	0.063	13%	0.13	C	C	.	.	H	α-helix	trans	-57.8	-35.5	178.6	-170.3	0	0	0	0	112.3	Y279 V280 T286 N287 K430	Y279-S283 WeakPolarHBondContact O-CB 3.45Å; Y279-S283 PolarHBondContact O-N 3.24Å; V280-S283 PolarHBondContact O-N 2.96Å; S283-T286 PolarHBondContact O-OG1 2.96Å; S283-N287 PolarHBondContact O-OD1 2.9Å; S283-K430 PolarHBondContact O-NZ 3.34Å; S283-K430 PolarHBondContact OG-NZ 3.25Å
284	A	93.1	Very high	90.2	Very high	0 Å²	0	28.9 Å²	28.9	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-69.1	-49.6	174	0	0	0	0	0	112	V280 T281 W282 T286 N287 V427 K430 M431	V280-A284 WeakPolarHBondContact O-CB 3.42Å; V280-A284 PolarHBondContact O-N 3.41Å; T281-A284 PolarHBondContact O-N 2.99Å; W282-A284 PolarHBondContact O-N 3.14Å; A284-T286 VanDerWaalsContact C-N 3.28Å; A284-T286 PolarHBondContact O-N 2.82Å; A284-N287 PolarHBondContact O-N 3.14Å; A284-V427 HydrophobicContact CB-CG1 4.09Å; A284-V427 WeakPolarHBondContact O-CG2 3.3Å; A284-K430 HydrophobicContact CB-CB 3.79Å; A284-K430 HydrophobicContact CB-CD 4.25Å; A284-M431 HydrophobicContact CB-CG 3.84Å; A284-M431 HydrophobicContact CB-SD 3.78Å
285	M	91.1	Very high	89.2	Confident	0 Å²	0	30.1 Å²	30.1	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-63.1	-32.6	-178.3	-67.4	-177	-59.5	0	0	113	F222 Y226 N235 I239 T281 W282 N287 N288	F222-M285 HydrophobicContact CB-CE 3.93Å; F222-M285 HydrophobicContact CD1-CE 3.87Å; F222-M285 HydrophobicContact CD2-CE 3.88Å; F222-M285 HydrophobicContact CE1-CE 4.38Å; F222-M285 HydrophobicContact CE2-CE 4.37Å; F222-M285 HydrophobicContact CG-CE 3.62Å; Y226-M285 HydrophobicContact CD1-CB 3.9Å; Y226-M285 HydrophobicContact CD2-CE 4.46Å; Y226-M285 HydrophobicContact CE1-CB 4.33Å; Y226-M285 HydrophobicContact CG-CB 4.43Å; Y226-M285 HydrophobicContact CG-CE 4.3Å; Y226-M285 HydrophobicContact CG-SD 4.45Å; N235-M285 HydrophobicContact CB-CG 4.43Å; N235-M285 HydrophobicContact CB-SD 3.98Å; I239-M285 HydrophobicContact CD1-CE 4.39Å; I239-M285 HydrophobicContact CD1-SD 3.79Å; I239-M285 HydrophobicContact CG1-CE 4.12Å; I239-M285 HydrophobicContact CG1-SD 3.65Å; T281-M285 HydrophobicContact CG2-CE 4Å; T281-M285 HydrophobicContact CG2-SD 4.36Å; T281-M285 WeakPolarHBondContact O-CG 3.3Å; T281-M285 PolarHBondContact O-N 2.92Å; W282-M285 PolarHBondContact O-N 3.23Å; W282-M285 VanDerWaalsContact O-N 3.14Å; M285-N287 PolarHBondContact O-N 2.9Å; M285-N287 VanDerWaalsContact O-N 3.13Å; M285-N288 VanDerWaalsContact O-CB 3.32Å; M285-N288 WeakPolarHBondContact O-CB 3.39Å; M285-N288 PolarHBondContact O-N 3.34Å
286	T	87.9	Confident	87.7	Confident	13 Å²	13	30.5 Å²	30.5	8%	0.08	15%	0.148	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.6	-14.3	173.4	61.6	0	0	0	0	114.1	Y226 W282 S283 A284 N294	Y226-T286 HydrophobicContact CE1-CG2 4.21Å; Y226-T286 WeakPolarHBondContact OH-CG2 3.49Å; W282-T286 WeakPolarHBondContact O-CG2 3.33Å; W282-T286 PolarHBondContact O-N 3.35Å; S283-T286 PolarHBondContact O-OG1 2.96Å; A284-T286 VanDerWaalsContact C-N 3.28Å; A284-T286 PolarHBondContact O-N 2.82Å; T286-N294 PolarHBondContact O-ND2 2.95Å
287	N	88.1	Confident	85.7	Confident	3 Å²	3	33.4 Å²	33.4	2%	0.016	16%	0.164	C	C	.	.	T	Hydrogen-bonded Turn	trans	-101.8	8.1	173.4	-68.7	125.2	0	0	0	113.7	S283 A284 M285 N409 S422 T423 A426 V427 K430	S283-N287 PolarHBondContact O-OD1 2.9Å; A284-N287 PolarHBondContact O-N 3.14Å; M285-N287 PolarHBondContact O-N 2.9Å; M285-N287 VanDerWaalsContact O-N 3.13Å; N287-N409 PolarHBondContact ND2-O 3.49Å; N287-S422 WeakPolarHBondContact O-CB 3.48Å; N287-T423 PolarHBondContact O-N 3.48Å; N287-A426 HydrophobicContact CB-CB 4.15Å; N287-V427 VanDerWaalsContact C-CG2 3.46Å; N287-V427 HydrophobicContact CB-CG2 4Å; N287-V427 WeakPolarHBondContact O-CG2 3.49Å; N287-K430 PolarHBondContact OD1-NZ 3.08Å
288	N	88.9	Confident	83.6	Confident	2 Å²	2	37.9 Å²	37.9	1%	0.011	19%	0.187	C	C	.	.			trans	-64.1	126.5	172.4	-166.9	-42.5	0	0	0	109.4	E234 N235 M285 N290 N294	E234-N288 PolarHBondContact OE2-ND2 3.37Å; N235-N288 PolarHBondContact OD1-ND2 2.87Å; M285-N288 VanDerWaalsContact O-CB 3.32Å; M285-N288 WeakPolarHBondContact O-CB 3.39Å; M285-N288 PolarHBondContact O-N 3.34Å; N288-N290 PolarHBondContact O-N 3.47Å; N288-N290 WeakPolarHBondContact OD1-CB 3.49Å; N288-N290 PolarHBondContact OD1-N 2.69Å; N288-N294 PolarHBondContact O-ND2 2.93Å
289	P	85.7	Confident	81.7	Confident	55 Å²	55	39.2 Å²	39.2	36%	0.357	20%	0.198	S	C	.	.	S	Bend	trans	-66	-23.4	177.9	26.2	-34.7	0	0	0	113.5	R291 M424	P289-R291 PolarHBondContact O-N 3.47Å; P289-M424 VanDerWaalsContact CD-SD 3.54Å; P289-M424 HydrophobicContact CG-CE 3.73Å; P289-M424 HydrophobicContact CG-CG 3.9Å; P289-M424 HydrophobicContact CG-SD 4.03Å
290	N	84.5	Confident	79.8	Confident	56 Å²	56	39.9 Å²	39.9	30%	0.299	20%	0.203	S	C	.	.			trans	-71.8	101.1	176.2	-171.9	-11.9	0	0	0	110.5	N288 K292 C293 N294	N288-N290 PolarHBondContact O-N 3.47Å; N288-N290 WeakPolarHBondContact OD1-CB 3.49Å; N288-N290 PolarHBondContact OD1-N 2.69Å; N290-K292 PolarHBondContact O-N 3.2Å; N290-K292 WeakPolarHBondContact OD1-CB 3.29Å; N290-K292 PolarHBondContact OD1-N 3.28Å; N290-K292 VanDerWaalsContact OD1-N 3.09Å; N290-C293 HydrophobicContact CB-CB 4.32Å; N290-C293 PolarHBondContact ND2-SG 2.82Å; N290-C293 VanDerWaalsContact ND2-SG 3.36Å; N290-C293 PolarHBondContact O-N 3.36Å; N290-N294 PolarHBondContact O-N 3.28Å
291	R	77.1	Confident	77.9	Confident	154 Å²	154	43.5 Å²	43.5	58%	0.581	23%	0.225	S	C	*	.	G	3₁₀ helix	trans	-60.5	-25.1	-179.6	-65.4	-65.5	-173.2	169.9	-0.7	113.9	P289 C293 N294	P289-R291 PolarHBondContact O-N 3.47Å; R291-C293 PolarHBondContact O-N 3.43Å; R291-N294 CarbonylContact O-C 3.56Å; R291-N294 PolarHBondContact O-N 2.86Å
292	K	81.1	Confident	75.8	Confident	146 Å²	146	46.4 Å²	46.4	64%	0.635	25%	0.245	S	C	*	.	G	3₁₀ helix	trans	-68	-28.6	175.2	-62.4	-178.7	179.9	178.4	0	112.4	Q228 N290	Q228-K292 PolarHBondContact NE2-O 2.92Å; N290-K292 PolarHBondContact O-N 3.2Å; N290-K292 WeakPolarHBondContact OD1-CB 3.29Å; N290-K292 PolarHBondContact OD1-N 3.28Å; N290-K292 VanDerWaalsContact OD1-N 3.09Å
293	C	83	Confident	73.8	Confident	1 Å²	1	50.7 Å²	50.7	1%	0.007	27%	0.267	C	S	.	.	G	3₁₀ helix	trans	-101.1	0.2	-178.1	-54.7	0	0	0	0	112.8	Y226 C232 N235 N290 R291	Y226-C293 WeakPolarHBondContact CD1-O 3.19Å; C232-C293 WeakPolarHBondContact CA-SG 3.39Å; C232-C293 HydrophobicContact CB-CB 3.72Å; C232-C293 WeakPolarHBondContact CB-SG 3.45Å; C232-C293 WeakPolarHBondContact SG-CA 3.42Å; C232-C293 WeakPolarHBondContact SG-CB 3.5Å; C232-C293 CovalentContact SG-SG 2.02Å; C232-C293 PolarHBondContact SG-SG 2.87Å; N235-C293 PolarHBondContact ND2-O 3.15Å; N290-C293 HydrophobicContact CB-CB 4.32Å; N290-C293 PolarHBondContact ND2-SG 2.82Å; N290-C293 VanDerWaalsContact ND2-SG 3.36Å; N290-C293 PolarHBondContact O-N 3.36Å; R291-C293 PolarHBondContact O-N 3.43Å
294	N	81.4	Confident	71.8	Confident	15 Å²	15	54.2 Å²	54.2	8%	0.08	30%	0.296	C	S	.	.			trans	-136.1	73.8	-176.6	-178.3	13.3	0	0	0	109.6	T286 N288 N290 R291	T286-N294 PolarHBondContact O-ND2 2.95Å; N288-N294 PolarHBondContact O-ND2 2.93Å; N290-N294 PolarHBondContact O-N 3.28Å; R291-N294 CarbonylContact O-C 3.56Å; R291-N294 PolarHBondContact O-N 2.86Å
295	P	74.4	Confident	69.5	Low	27 Å²	27	61 Å²	61	18%	0.175	33%	0.332	C	S	.	.			trans	-70.7	138.6	174.4	30.6	-34.5	0	0	0	110.1	Y225 L300	Y225-P295 WeakPolarHBondContact O-CD 3.23Å; Y225-P295 VanDerWaalsContact O-CG 3.22Å; Y225-P295 WeakPolarHBondContact O-CG 3.39Å; P295-L300 HydrophobicContact CB-CD1 4.24Å; P295-L300 HydrophobicContact CB-CD2 4.22Å; P295-L300 HydrophobicContact CB-CG 4Å; P295-L300 HydrophobicContact CG-CD1 3.96Å; P295-L300 HydrophobicContact CG-CD2 4.11Å; P295-L300 HydrophobicContact CG-CG 4.12Å
296	S	65	Low	67.1	Low	53 Å²	53	65 Å²	65	37%	0.371	36%	0.357	S	S	.	.			trans	-71	147.4	172.3	66.6	0	0	0	0	110.1	L298 S299 L300	S296-L298 PolarHBondContact O-N 2.91Å; S296-L298 VanDerWaalsContact O-N 3.15Å; S296-S299 PolarHBondContact N-OG 3.46Å; S296-S299 VanDerWaalsContact N-OG 3.14Å; S296-S299 WeakPolarHBondContact O-CB 3.46Å; S296-S299 PolarHBondContact O-N 3.3Å; S296-S299 PolarHBondContact O-OG 3.48Å; S296-S299 WeakPolarHBondContact OG-CB 3.48Å; S296-S299 PolarHBondContact OG-N 3.46Å; S296-S299 PolarHBondContact OG-OG 2.83Å; S296-L300 PolarHBondContact O-N 3.28Å; S296-L300 VanDerWaalsContact O-N 3.09Å
297	L	53.9	Low	64.7	Low	78 Å²	78	71.9 Å²	71.9	41%	0.408	40%	0.4	S	S	.	.	H	α-helix	trans	-57.5	-32.2	179.8	-170.4	143.3	0	0	0	111.9	L300 V301 A325	L297-L300 PolarHBondContact O-N 3.2Å; L297-V301 HydrophobicContact CD2-CG2 4.21Å; L297-V301 WeakPolarHBondContact O-CG2 3.48Å; L297-V301 PolarHBondContact O-N 3.25Å; L297-A325 HydrophobicContact CD1-CB 3.94Å
298	L	50.7	Low	62.2	Low	95 Å²	95	75 Å²	75	50%	0.497	43%	0.426	S	S	.	.	H	α-helix	trans	-67.1	-40.8	173.5	-171	67.4	0	0	0	112.8	S296 L300 S302 H319	S296-L298 PolarHBondContact O-N 2.91Å; S296-L298 VanDerWaalsContact O-N 3.15Å; L298-L300 VanDerWaalsContact C-N 3.29Å; L298-L300 PolarHBondContact O-N 3.27Å; L298-S302 WeakPolarHBondContact O-CB 3.31Å; L298-S302 PolarHBondContact O-N 3.25Å; L298-S302 PolarHBondContact O-OG 2.89Å; L298-H319 HydrophobicContact CD2-CB 4.48Å
299	S	56.5	Low	59.4	Low	35 Å²	35	81.3 Å²	81.3	25%	0.245	47%	0.465	C	S	.	.	H	α-helix	trans	-62.9	-38.1	175.2	69.7	0	0	0	0	111.5	S296 S302 H303	S296-S299 PolarHBondContact N-OG 3.46Å; S296-S299 VanDerWaalsContact N-OG 3.14Å; S296-S299 WeakPolarHBondContact O-CB 3.46Å; S296-S299 PolarHBondContact O-N 3.3Å; S296-S299 PolarHBondContact O-OG 3.48Å; S296-S299 WeakPolarHBondContact OG-CB 3.48Å; S296-S299 PolarHBondContact OG-N 3.46Å; S296-S299 PolarHBondContact OG-OG 2.83Å; S299-S302 WeakPolarHBondContact CA-OG 3.37Å; S299-S302 PolarHBondContact O-N 3.48Å; S299-S302 PolarHBondContact O-OG 3.41Å; S299-H303 PolarHBondContact O-CD2 3.42Å; S299-H303 PolarHBondContact O-N 3.33Å
300	L	56	Low	57.1	Low	40 Å²	40	87.6 Å²	87.6	21%	0.209	49%	0.489	C	S	.	.	H	α-helix	trans	-66	-47.5	177.7	-73.4	165	0	0	0	113	Y225 P295 S296 L297 L298 S302 H303 A304	Y225-L300 HydrophobicContact CD1-CD2 3.14Å; Y225-L300 HydrophobicContact CD1-CG 4.41Å; Y225-L300 HydrophobicContact CE1-CD2 3.57Å; Y225-L300 HydrophobicContact CG-CD1 4.36Å; Y225-L300 HydrophobicContact CG-CD2 3.76Å; P295-L300 HydrophobicContact CB-CD1 4.24Å; P295-L300 HydrophobicContact CB-CD2 4.22Å; P295-L300 HydrophobicContact CB-CG 4Å; P295-L300 HydrophobicContact CG-CD1 3.96Å; P295-L300 HydrophobicContact CG-CD2 4.11Å; P295-L300 HydrophobicContact CG-CG 4.12Å; S296-L300 PolarHBondContact O-N 3.28Å; S296-L300 VanDerWaalsContact O-N 3.09Å; L297-L300 PolarHBondContact O-N 3.2Å; L298-L300 VanDerWaalsContact C-N 3.29Å; L298-L300 PolarHBondContact O-N 3.27Å; L300-S302 VanDerWaalsContact C-N 3.33Å; L300-S302 PolarHBondContact O-N 3.03Å; L300-H303 PolarHBondContact O-N 3.37Å; L300-A304 PolarHBondContact O-N 3.06Å; L300-A304 VanDerWaalsContact O-N 3.16Å
301	V	55.6	Low	54.6	Low	81 Å²	81	90.6 Å²	90.6	49%	0.491	51%	0.511	S	S	.	.	H	α-helix	trans	-67.6	-35.3	177.9	175.2	0	0	0	0	111.3	L297 A304 N305	L297-V301 HydrophobicContact CD2-CG2 4.21Å; L297-V301 WeakPolarHBondContact O-CG2 3.48Å; L297-V301 PolarHBondContact O-N 3.25Å; V301-A304 PolarHBondContact O-N 3.41Å; V301-N305 PolarHBondContact O-N 3.5Å
302	S	51.5	Low	52.3	Low	60 Å²	60	89.4 Å²	89.4	42%	0.42	52%	0.521	S	S	.	.	H	α-helix	trans	-67.5	-36.6	176.4	70.6	0	0	0	0	113	L298 S299 L300 N305 T306	L298-S302 WeakPolarHBondContact O-CB 3.31Å; L298-S302 PolarHBondContact O-N 3.25Å; L298-S302 PolarHBondContact O-OG 2.89Å; S299-S302 WeakPolarHBondContact CA-OG 3.37Å; S299-S302 PolarHBondContact O-N 3.48Å; S299-S302 PolarHBondContact O-OG 3.41Å; L300-S302 VanDerWaalsContact C-N 3.33Å; L300-S302 PolarHBondContact O-N 3.03Å; S302-N305 PolarHBondContact O-N 2.96Å; S302-T306 PolarHBondContact O-N 2.93Å; S302-T306 PolarHBondContact O-OG1 3.44Å
303	H	51	Low	49.8	Very low	142 Å²	142	87.2 Å²	87.2	66%	0.657	53%	0.531	S	S	*	.	H	α-helix	trans	-69.6	-31.5	174.6	-85	-58.8	0	0	0	112.9	S299 L300 N305 T306	S299-H303 PolarHBondContact O-CD2 3.42Å; S299-H303 PolarHBondContact O-N 3.33Å; L300-H303 PolarHBondContact O-N 3.37Å; H303-N305 PolarHBondContact O-N 3.31Å; H303-T306 PolarHBondContact O-N 3.18Å
304	A	50.7	Low	47.1	Very low	83 Å²	83	91 Å²	91	69%	0.686	56%	0.557	S	S	*	*	H	α-helix	trans	-66.9	-24.8	175.6	0	0	0	0	0	113.2	L300 V301	L300-A304 PolarHBondContact O-N 3.06Å; L300-A304 VanDerWaalsContact O-N 3.16Å; V301-A304 PolarHBondContact O-N 3.41Å
305	N	45.6	Very low	44.9	Very low	141 Å²	141	97 Å²	97	75%	0.754	60%	0.597	S	S	*	*	T	Hydrogen-bonded Turn	trans	-99.5	0	-179.1	-85.7	1.3	0	0	0	114.7	V301 S302 H303	V301-N305 PolarHBondContact O-N 3.5Å; S302-N305 PolarHBondContact O-N 2.96Å; H303-N305 PolarHBondContact O-N 3.31Å
306	T	40.1	Very low	42.8	Very low	84 Å²	84	99.2 Å²	99.2	52%	0.515	63%	0.625	S	S	.	*			trans	-127.4	95	-175.2	46.1	0	0	0	0	113.2	S302 H303 A308	S302-T306 PolarHBondContact O-N 2.93Å; S302-T306 PolarHBondContact O-OG1 3.44Å; H303-T306 PolarHBondContact O-N 3.18Å; T306-A308 PolarHBondContact O-N 3.21Å
307	T	37.3	Very low	41.1	Very low	159 Å²	159	101.1 Å²	101.1	98%	0.975	64%	0.638	S	S	*	*			trans	-82.9	25.6	160.5	29.2	0	0	0	0	113.1
308	A	36.3	Very low	40.4	Very low	69 Å²	69	99.7 Å²	99.7	57%	0.57	64%	0.642	S	S	*	*	S	Bend	trans	-133.5	115.2	-177.1	0	0	0	0	0	112.4	T306	T306-A308 PolarHBondContact O-N 3.21Å
309	T	31.1	Very low	39.8	Very low	134 Å²	134	102.7 Å²	102.7	82%	0.822	65%	0.653	S	S	*	*			trans	39.3	116.2	150.7	37	0	0	0	0	118.9	P311	T309-P311 WeakPolarHBondContact O-CD 3.41Å
310	Q	36.6	Very low	39.3	Very low	187 Å²	187	104 Å²	104	87%	0.874	66%	0.659	S	S	*	*			trans	-48	141.3	165.3	-69.1	-162.6	-17.6	0	0	113
311	P	31.6	Very low	39.1	Very low	118 Å²	118	104.2 Å²	104.2	77%	0.766	66%	0.659	S	S	*	*			trans	-113	134.8	133.8	8.3	11.5	0	0	0	109.5	T309 A313	T309-P311 WeakPolarHBondContact O-CD 3.41Å; P311-A313 PolarHBondContact O-N 3.34Å
312	T	30.1	Very low	38.8	Very low	129 Å²	129	105.5 Å²	105.5	79%	0.791	66%	0.656	S	S	*	*			trans	-37.7	119.8	168.6	37.9	0	0	0	0	112.5	S314	T312-S314 PolarHBondContact O-N 3.37Å
313	A	28.7	Very low	39.3	Very low	100 Å²	100	105.9 Å²	105.9	83%	0.826	65%	0.648	S	S	*	*			trans	-62.5	114.5	175	0	0	0	0	0	110.6	P311	P311-A313 PolarHBondContact O-N 3.34Å
314	S	25.4	Very low	40.3	Very low	81 Å²	81	100.3 Å²	100.3	57%	0.566	62%	0.623	S	S	*	*			trans	-68	129.6	162.1	50.5	0	0	0	0	109.7	T312 G316	T312-S314 PolarHBondContact O-N 3.37Å; S314-G316 PolarHBondContact O-N 2.86Å
315	P	34.6	Very low	41.7	Very low	142 Å²	142	97.8 Å²	97.8	92%	0.922	60%	0.602	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.9	92.2	176.7	30.2	-30.8	0	0	0	109
316	G	31	Very low	43.6	Very low	73 Å²	73	91.3 Å²	91.3	75%	0.753	57%	0.567	S	S	*	*	T	Hydrogen-bonded Turn	trans	173.1	-22.5	176.4	0	0	0	0	0	117	S314 G318	S314-G316 PolarHBondContact O-N 2.86Å; G316-G318 VanDerWaalsContact C-N 3.31Å; G316-G318 PolarHBondContact O-N 3.44Å; G316-G318 VanDerWaalsContact O-N 3.17Å
317	S	29.8	Very low	45.8	Very low	93 Å²	93	87.8 Å²	87.8	65%	0.65	55%	0.548	S	S	*	.			trans	-93.5	55.8	-179.2	61.7	0	0	0	0	112.2	H319	S317-H319 PolarHBondContact O-N 3.05Å; S317-H319 VanDerWaalsContact O-N 3.08Å
318	G	37.9	Very low	48.3	Very low	47 Å²	47	83.8 Å²	83.8	49%	0.485	52%	0.519	S	S	.	.			trans	-72.3	96.9	170.1	0	0	0	0	0	109.8	K86 G316 V320	K86-G318 PolarHBondContact NZ-O 3.18Å; G316-G318 VanDerWaalsContact C-N 3.31Å; G316-G318 PolarHBondContact O-N 3.44Å; G316-G318 VanDerWaalsContact O-N 3.17Å; G318-V320 VanDerWaalsContact C-N 3.33Å; G318-V320 PolarHBondContact O-N 3.24Å
319	H	37.6	Very low	50.9	Low	158 Å²	158	83.3 Å²	83.3	73%	0.731	51%	0.509	S	S	*	.			trans	-60.4	102.2	157.2	-94.4	-81.4	0	0	0	106.8	L298 S317 Q321	L298-H319 HydrophobicContact CD2-CB 4.48Å; S317-H319 PolarHBondContact O-N 3.05Å; S317-H319 VanDerWaalsContact O-N 3.08Å; H319-Q321 PolarHBondContact O-N 2.99Å; H319-Q321 VanDerWaalsContact O-N 3.14Å
320	V	46	Very low	53.9	Low	63 Å²	63	76.9 Å²	76.9	38%	0.382	47%	0.47	S	S	.	.			trans	-70.2	110	172.5	-158.2	0	0	0	0	104.9	K86 V89 G318 W322	K86-V320 HydrophobicContact CD-CG2 3.91Å; V89-V320 HydrophobicContact CG1-CG1 4.18Å; V89-V320 HydrophobicContact CG2-CB 4.23Å; V89-V320 HydrophobicContact CG2-CG2 4.43Å; G318-V320 VanDerWaalsContact C-N 3.33Å; G318-V320 PolarHBondContact O-N 3.24Å; V320-W322 PolarHBondContact O-N 3.14Å; V320-W322 VanDerWaalsContact O-N 3.16Å
321	Q	52.1	Low	56.6	Low	44 Å²	44	69.1 Å²	69.1	21%	0.206	43%	0.434	C	S	.	.			trans	-66.9	115.1	-176.4	-154	175	-50.9	0	0	107.5	H319 W323	H319-Q321 PolarHBondContact O-N 2.99Å; H319-Q321 VanDerWaalsContact O-N 3.14Å; Q321-W323 PolarHBondContact NE2-O 3.33Å; Q321-W323 PolarHBondContact O-N 2.64Å
322	W	49.2	Very low	59.6	Low	109 Å²	109	67.7 Å²	67.7	41%	0.413	42%	0.423	S	S	.	.	S	Bend	trans	-64	-40.6	-171.1	159.5	78.4	0	0	0	111.7	I57 L58 V320	I57-W322 PolarHBondContact O-NE1 3.01Å; L58-W322 HydrophobicContact CD2-CH2 3.94Å; L58-W322 HydrophobicContact CD2-CZ2 3.34Å; L58-W322 HydrophobicContact CG-CZ2 4.32Å; V320-W322 PolarHBondContact O-N 3.14Å; V320-W322 VanDerWaalsContact O-N 3.16Å
323	W	62.2	Low	62.6	Low	68 Å²	68	62.9 Å²	62.9	26%	0.258	39%	0.392	S	S	.	.	S	Bend	trans	-127	120.8	171.1	-86.9	42.2	0	0	0	109.4	V54 Q321 I328 L331	V54-W323 HydrophobicContact CG1-CZ2 3.86Å; V54-W323 HydrophobicContact CG2-CZ2 4.2Å; Q321-W323 PolarHBondContact NE2-O 3.33Å; Q321-W323 PolarHBondContact O-N 2.64Å; W323-I328 HydrophobicContact CD2-CG1 4.36Å; W323-I328 HydrophobicContact CE3-CB 4.41Å; W323-I328 HydrophobicContact CE3-CD1 3.84Å; W323-I328 HydrophobicContact CE3-CG1 3.19Å; W323-I328 HydrophobicContact CZ3-CB 4.31Å; W323-I328 HydrophobicContact CZ3-CD1 4.41Å; W323-I328 HydrophobicContact CZ3-CG1 3.48Å; W323-I328 VanDerWaalsContact CZ3-CG1 3.48Å; W323-L331 HydrophobicContact CH2-CD2 3.87Å
324	D	71.7	Confident	65.7	Low	24 Å²	24	58.1 Å²	58.1	13%	0.128	35%	0.353	C	S	.	.			trans	-83.8	142.4	165	-71.5	-36.6	0	0	0	108.2	Q326 G327	D324-Q326 VanDerWaalsContact C-N 3.29Å; D324-Q326 VanDerWaalsContact CA-OE1 3.23Å; D324-Q326 PolarHBondContact O-N 3.25Å; D324-Q326 PolarHBondContact O-OE1 2.96Å; D324-G327 PolarHBondContact O-N 3.43Å
325	A	80.3	Confident	69	Low	30 Å²	30	57.2 Å²	57.2	25%	0.248	34%	0.342	C	S	.	.	H	α-helix	trans	-65.7	-29	-171.6	0	0	0	0	0	113.9	W282 L297 G327 I328 V329	W282-A325 HydrophobicContact CH2-CB 3.74Å; W282-A325 HydrophobicContact CZ2-CB 4.25Å; L297-A325 HydrophobicContact CD1-CB 3.94Å; A325-G327 VanDerWaalsContact C-N 3.27Å; A325-G327 PolarHBondContact O-N 3.2Å; A325-I328 WeakPolarHBondContact O-CB 3.35Å; A325-I328 PolarHBondContact O-N 2.9Å; A325-V329 WeakPolarHBondContact O-CG2 3.49Å; A325-V329 PolarHBondContact O-N 3.23Å
326	Q	85.8	Confident	71.8	Confident	5 Å²	5	54.1 Å²	54.1	2%	0.023	31%	0.314	C	S	.	.	H	α-helix	trans	-58.6	-34.5	170.1	93.2	-49.7	-7.1	0	0	112.6	Y279 W282 D324 V329 G330 N409	Y279-Q326 WeakPolarHBondContact CE2-O 3.25Å; Y279-Q326 PolarHBondContact OH-O 3.49Å; W282-Q326 HydrophobicContact CD2-CB 4.12Å; W282-Q326 HydrophobicContact CE3-CB 3.82Å; W282-Q326 HydrophobicContact CH2-CB 3.9Å; W282-Q326 HydrophobicContact CZ2-CB 4.15Å; W282-Q326 VanDerWaalsContact CZ3-CA 3.46Å; W282-Q326 HydrophobicContact CZ3-CB 3.72Å; D324-Q326 VanDerWaalsContact C-N 3.29Å; D324-Q326 VanDerWaalsContact CA-OE1 3.23Å; D324-Q326 PolarHBondContact O-N 3.25Å; D324-Q326 PolarHBondContact O-OE1 2.96Å; Q326-V329 PolarHBondContact O-N 3.46Å; Q326-G330 PolarHBondContact O-N 3.27Å; Q326-N409 PolarHBondContact NE2-OD1 2.78Å
327	G	86.9	Confident	74.7	Confident	11 Å²	11	50.7 Å²	50.7	11%	0.113	28%	0.278	C	S	.	.	H	α-helix	trans	-72.4	-36.4	-177.2	0	0	0	0	0	110.6	D324 A325 G330 L331	D324-G327 PolarHBondContact O-N 3.43Å; A325-G327 VanDerWaalsContact C-N 3.27Å; A325-G327 PolarHBondContact O-N 3.2Å; G327-G330 PolarHBondContact O-N 3.08Å; G327-L331 WeakPolarHBondContact O-CB 3.28Å; G327-L331 PolarHBondContact O-N 3.48Å
328	I	89.2	Confident	77.5	Confident	74 Å²	74	46.3 Å²	46.3	38%	0.379	25%	0.247	S	C	.	.	H	α-helix	trans	-59.2	-54.3	170.8	-60.3	168.1	0	0	0	110	W323 A325 G330 L331 V332	W323-I328 HydrophobicContact CD2-CG1 4.36Å; W323-I328 HydrophobicContact CE3-CB 4.41Å; W323-I328 HydrophobicContact CE3-CD1 3.84Å; W323-I328 HydrophobicContact CE3-CG1 3.19Å; W323-I328 HydrophobicContact CZ3-CB 4.31Å; W323-I328 HydrophobicContact CZ3-CD1 4.41Å; W323-I328 HydrophobicContact CZ3-CG1 3.48Å; W323-I328 VanDerWaalsContact CZ3-CG1 3.48Å; A325-I328 WeakPolarHBondContact O-CB 3.35Å; A325-I328 PolarHBondContact O-N 2.9Å; I328-G330 VanDerWaalsContact C-N 3.26Å; I328-G330 PolarHBondContact O-N 3.3Å; I328-L331 WeakPolarHBondContact O-CB 3.24Å; I328-L331 PolarHBondContact O-N 2.82Å; I328-L331 VanDerWaalsContact O-N 3.11Å; I328-V332 WeakPolarHBondContact O-CG2 3.48Å; I328-V332 PolarHBondContact O-N 2.93Å
329	V	92	Very high	80	Confident	59 Å²	59	47.4 Å²	47.4	36%	0.358	24%	0.242	S	C	.	.	H	α-helix	trans	-60.2	-42.5	-178.8	177.8	0	0	0	0	109.8	Y279 W282 A325 Q326 L331 V332 I333	Y279-V329 HydrophobicContact CD2-CB 4.05Å; Y279-V329 HydrophobicContact CD2-CG1 3.48Å; Y279-V329 VanDerWaalsContact CD2-CG1 3.48Å; Y279-V329 HydrophobicContact CE2-CB 3.76Å; Y279-V329 HydrophobicContact CE2-CG1 3.59Å; Y279-V329 HydrophobicContact CG-CG1 4.22Å; W282-V329 HydrophobicContact CZ3-CG2 4.45Å; A325-V329 WeakPolarHBondContact O-CG2 3.49Å; A325-V329 PolarHBondContact O-N 3.23Å; Q326-V329 PolarHBondContact O-N 3.46Å; V329-L331 VanDerWaalsContact C-N 3.34Å; V329-L331 PolarHBondContact O-N 2.99Å; V329-V332 PolarHBondContact O-N 3.48Å; V329-I333 HydrophobicContact CG1-CD1 3.83Å; V329-I333 HydrophobicContact CG1-CG1 4.43Å; V329-I333 VanDerWaalsContact O-CG1 3.3Å; V329-I333 WeakPolarHBondContact O-CG1 3.37Å; V329-I333 PolarHBondContact O-N 3.33Å
330	G	92.8	Very high	82.3	Confident	0 Å²	0	41.5 Å²	41.5	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-60.7	-38.4	174.9	0	0	0	0	0	114.4	Y279 Q326 G327 I328 F334	Y279-G330 WeakPolarHBondContact OH-CA 3.33Å; Y279-G330 PolarHBondContact OH-N 3.23Å; Q326-G330 PolarHBondContact O-N 3.27Å; G327-G330 PolarHBondContact O-N 3.08Å; I328-G330 VanDerWaalsContact C-N 3.26Å; I328-G330 PolarHBondContact O-N 3.3Å; G330-F334 VanDerWaalsContact O-CB 3.25Å; G330-F334 WeakPolarHBondContact O-CB 3.47Å; G330-F334 PolarHBondContact O-N 3.14Å
331	L	93	Very high	84.2	Confident	23 Å²	23	39.3 Å²	39.3	12%	0.12	20%	0.202	C	C	.	.	H	α-helix	trans	-68.6	-41.4	175.3	-172	66.7	0	0	0	111.2	T50 W323 G327 I328 V329 F334 L335 I403	T50-L331 HydrophobicContact CG2-CD1 3.93Å; W323-L331 HydrophobicContact CH2-CD2 3.87Å; G327-L331 WeakPolarHBondContact O-CB 3.28Å; G327-L331 PolarHBondContact O-N 3.48Å; I328-L331 WeakPolarHBondContact O-CB 3.24Å; I328-L331 PolarHBondContact O-N 2.82Å; I328-L331 VanDerWaalsContact O-N 3.11Å; V329-L331 VanDerWaalsContact C-N 3.34Å; V329-L331 PolarHBondContact O-N 2.99Å; L331-F334 HydrophobicContact CD1-CD1 4.26Å; L331-F334 WeakPolarHBondContact O-CB 3.38Å; L331-F334 PolarHBondContact O-N 2.93Å; L331-L335 VanDerWaalsContact O-CG 3.26Å; L331-L335 WeakPolarHBondContact O-CG 3.28Å; L331-L335 PolarHBondContact O-N 3.47Å; L331-I403 HydrophobicContact CD1-CD1 3.59Å
332	V	94.4	Very high	85.7	Confident	88 Å²	88	37.2 Å²	37.2	53%	0.533	19%	0.192	S	C	.	.	H	α-helix	trans	-62.2	-46.6	176.1	172.3	0	0	0	0	111.1	I328 V329 F334 L335 F336	I328-V332 WeakPolarHBondContact O-CG2 3.48Å; I328-V332 PolarHBondContact O-N 2.93Å; V329-V332 PolarHBondContact O-N 3.48Å; V332-F334 VanDerWaalsContact C-N 3.32Å; V332-F334 PolarHBondContact O-N 3.22Å; V332-L335 PolarHBondContact O-N 3.47Å; V332-F336 WeakPolarHBondContact O-CB 3.48Å; V332-F336 PolarHBondContact O-N 2.83Å
333	I	94.3	Very high	87.1	Confident	28 Å²	28	37 Å²	37	14%	0.144	20%	0.198	C	C	.	.	H	α-helix	trans	-63.1	-41.6	177.1	-63.2	165.5	0	0	0	110.4	Q173 L177 Y276 Y279 V329 F336 C337	Q173-I333 HydrophobicContact CG-CG2 4.21Å; L177-I333 HydrophobicContact CD1-CG2 4.17Å; Y276-I333 HydrophobicContact CD2-CD1 4.19Å; Y276-I333 HydrophobicContact CE2-CD1 4.24Å; Y276-I333 HydrophobicContact CE2-CG2 4.16Å; Y279-I333 HydrophobicContact CD1-CD1 3.59Å; Y279-I333 HydrophobicContact CD2-CD1 4.45Å; Y279-I333 HydrophobicContact CE1-CD1 3.62Å; Y279-I333 HydrophobicContact CE2-CD1 4.47Å; Y279-I333 HydrophobicContact CG-CD1 4.04Å; V329-I333 HydrophobicContact CG1-CD1 3.83Å; V329-I333 HydrophobicContact CG1-CG1 4.43Å; V329-I333 VanDerWaalsContact O-CG1 3.3Å; V329-I333 WeakPolarHBondContact O-CG1 3.37Å; V329-I333 PolarHBondContact O-N 3.33Å; I333-F336 PolarHBondContact O-N 3.22Å; I333-C337 WeakPolarHBondContact O-CB 3.33Å; I333-C337 PolarHBondContact O-N 2.88Å; I333-C337 PolarHBondContact O-SG 3.37Å; I333-C337 VanDerWaalsContact O-SG 3.39Å
334	F	94.4	Very high	87.6	Confident	0 Å²	0	35.4 Å²	35.4	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-56.5	-52.1	173.7	164.7	-88.5	0	0	0	112	L46 L47 F169 G330 L331 V332 F336 C337 T338 A399 Y402 I403	L46-F334 HydrophobicContact CD2-CE2 4.31Å; L46-F334 HydrophobicContact CD2-CZ 3.71Å; L46-F334 HydrophobicContact CG-CZ 4.08Å; L47-F334 HydrophobicContact CD2-CE1 4.19Å; F169-F334 AromaticContact CE1-CD2 3.81Å; F169-F334 HydrophobicContact CE1-CD2 3.81Å; F169-F334 HydrophobicContact CE1-CE2 4.46Å; F169-F334 AromaticContact CZ-CD2 3.58Å; F169-F334 HydrophobicContact CZ-CD2 3.58Å; F169-F334 AromaticContact CZ-CE2 3.94Å; F169-F334 HydrophobicContact CZ-CE2 3.94Å; G330-F334 VanDerWaalsContact O-CB 3.25Å; G330-F334 WeakPolarHBondContact O-CB 3.47Å; G330-F334 PolarHBondContact O-N 3.14Å; L331-F334 HydrophobicContact CD1-CD1 4.26Å; L331-F334 WeakPolarHBondContact O-CB 3.38Å; L331-F334 PolarHBondContact O-N 2.93Å; V332-F334 VanDerWaalsContact C-N 3.32Å; V332-F334 PolarHBondContact O-N 3.22Å; F334-F336 VanDerWaalsContact C-N 3.3Å; F334-F336 PolarHBondContact O-N 3.16Å; F334-C337 PolarHBondContact O-N 3.2Å; F334-T338 WeakPolarHBondContact O-CB 3.13Å; F334-T338 PolarHBondContact O-N 3.44Å; F334-T338 PolarHBondContact O-OG1 3.43Å; F334-T338 VanDerWaalsContact O-OG1 3.1Å; F334-A399 HydrophobicContact CE2-CB 3.78Å; F334-A399 HydrophobicContact CZ-CB 4.42Å; F334-Y402 HydrophobicContact CB-CE1 4Å; F334-Y402 AromaticContact CD2-CD1 3.8Å; F334-Y402 HydrophobicContact CD2-CD1 3.8Å; F334-Y402 HydrophobicContact CD2-CE1 4.15Å; F334-Y402 HydrophobicContact CE2-CD1 4.49Å; F334-Y402 HydrophobicContact CG-CE1 4.45Å; F334-I403 HydrophobicContact CB-CD1 4.43Å; F334-I403 HydrophobicContact CD1-CD1 3.62Å; F334-I403 HydrophobicContact CD1-CG1 4.26Å; F334-I403 HydrophobicContact CD2-CD1 3.75Å; F334-I403 HydrophobicContact CD2-CG1 3.93Å; F334-I403 HydrophobicContact CE1-CD1 3.66Å; F334-I403 HydrophobicContact CE1-CG1 3.82Å; F334-I403 HydrophobicContact CE2-CD1 3.74Å; F334-I403 HydrophobicContact CE2-CG1 3.41Å; F334-I403 VanDerWaalsContact CE2-CG1 3.41Å; F334-I403 HydrophobicContact CG-CD1 3.68Å; F334-I403 HydrophobicContact CG-CG1 4.31Å; F334-I403 HydrophobicContact CZ-CD1 3.7Å; F334-I403 HydrophobicContact CZ-CG1 3.36Å
335	L	93.4	Very high	86.8	Confident	63 Å²	63	38.1 Å²	38.1	33%	0.33	21%	0.213	S	C	.	.	H	α-helix	trans	-58.6	-45.7	-179.4	-70.4	175.7	0	0	0	110.9	L47 L331 V332 L339	L47-L335 HydrophobicContact CD2-CD2 3.17Å; L47-L335 HydrophobicContact CG-CD2 4.44Å; L331-L335 VanDerWaalsContact O-CG 3.26Å; L331-L335 WeakPolarHBondContact O-CG 3.28Å; L331-L335 PolarHBondContact O-N 3.47Å; V332-L335 PolarHBondContact O-N 3.47Å; L335-L339 WeakPolarHBondContact O-CB 3.48Å; L335-L339 VanDerWaalsContact O-CG 3.27Å; L335-L339 WeakPolarHBondContact O-CG 3.41Å; L335-L339 PolarHBondContact O-N 3.36Å
336	F	93.4	Very high	85.3	Confident	77 Å²	77	38 Å²	38	34%	0.338	21%	0.211	S	C	.	.	H	α-helix	trans	-58.1	-53.3	176.2	173.5	-99.2	0	0	0	111.7	L177 F180 V332 I333 F334 T338 L339 Y340	L177-F336 HydrophobicContact CD2-CD1 4.14Å; L177-F336 HydrophobicContact CD2-CE1 3.94Å; F180-F336 AromaticContact CD1-CE1 3.99Å; F180-F336 HydrophobicContact CD1-CE1 3.99Å; F180-F336 AromaticContact CD1-CZ 3.76Å; F180-F336 HydrophobicContact CD1-CZ 3.76Å; F180-F336 HydrophobicContact CD2-CE1 4.49Å; F180-F336 AromaticContact CD2-CZ 3.72Å; F180-F336 HydrophobicContact CD2-CZ 3.72Å; F180-F336 HydrophobicContact CE1-CE1 4.27Å; F180-F336 AromaticContact CE1-CZ 3.74Å; F180-F336 HydrophobicContact CE1-CZ 3.74Å; F180-F336 HydrophobicContact CE2-CE2 4.35Å; F180-F336 AromaticContact CE2-CZ 3.71Å; F180-F336 HydrophobicContact CE2-CZ 3.71Å; F180-F336 HydrophobicContact CG-CE1 4.09Å; F180-F336 AromaticContact CG-CZ 3.74Å; F180-F336 HydrophobicContact CG-CZ 3.74Å; F180-F336 HydrophobicContact CZ-CE2 4.32Å; F180-F336 AromaticContact CZ-CZ 3.71Å; F180-F336 HydrophobicContact CZ-CZ 3.71Å; V332-F336 WeakPolarHBondContact O-CB 3.48Å; V332-F336 PolarHBondContact O-N 2.83Å; I333-F336 PolarHBondContact O-N 3.22Å; F334-F336 VanDerWaalsContact C-N 3.3Å; F334-F336 PolarHBondContact O-N 3.16Å; F336-T338 PolarHBondContact O-N 2.79Å; F336-L339 PolarHBondContact O-N 2.72Å; F336-Y340 VanDerWaalsContact O-CB 3.24Å; F336-Y340 WeakPolarHBondContact O-CB 3.37Å; F336-Y340 PolarHBondContact O-N 2.95Å
337	C	91.9	Very high	83.4	Confident	1 Å²	1	42.5 Å²	42.5	1%	0.007	24%	0.239	C	C	.	.	H	α-helix	trans	-66	-38.1	-177.4	-69.7	0	0	0	0	112.8	Q173 L176 I333 F334 Y340 A341	Q173-C337 HydrophobicContact CG-CB 4.16Å; L176-C337 HydrophobicContact CD1-CB 4.23Å; I333-C337 WeakPolarHBondContact O-CB 3.33Å; I333-C337 PolarHBondContact O-N 2.88Å; I333-C337 PolarHBondContact O-SG 3.37Å; I333-C337 VanDerWaalsContact O-SG 3.39Å; F334-C337 PolarHBondContact O-N 3.2Å; C337-Y340 PolarHBondContact O-N 3.21Å; C337-A341 WeakPolarHBondContact O-CB 3.4Å; C337-A341 PolarHBondContact O-N 3.41Å
338	T	89.4	Confident	81.7	Confident	0 Å²	0	44 Å²	44	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-65.3	-45.4	176.3	-63.1	0	0	0	0	111.3	L46 F334 F336 Y340 A341 S342 L396	L46-T338 HydrophobicContact CD2-CG2 4.2Å; F334-T338 WeakPolarHBondContact O-CB 3.13Å; F334-T338 PolarHBondContact O-N 3.44Å; F334-T338 PolarHBondContact O-OG1 3.43Å; F334-T338 VanDerWaalsContact O-OG1 3.1Å; F336-T338 PolarHBondContact O-N 2.79Å; T338-Y340 VanDerWaalsContact C-N 3.34Å; T338-A341 PolarHBondContact O-N 3.34Å; T338-S342 WeakPolarHBondContact O-CB 3.41Å; T338-S342 PolarHBondContact O-N 2.83Å; T338-S342 VanDerWaalsContact O-N 3.15Å; T338-S342 PolarHBondContact O-OG 2.86Å; T338-S342 VanDerWaalsContact O-OG 3.06Å; T338-L396 HydrophobicContact CG2-CD2 4.41Å
339	L	89.3	Confident	80	Confident	71 Å²	71	41.3 Å²	41.3	37%	0.372	23%	0.233	S	C	.	.	H	α-helix	trans	-64.5	-42	176.1	-70.9	173.1	0	0	0	111.3	L335 F336 A341 S342 I343	L335-L339 WeakPolarHBondContact O-CB 3.48Å; L335-L339 VanDerWaalsContact O-CG 3.27Å; L335-L339 WeakPolarHBondContact O-CG 3.41Å; L335-L339 PolarHBondContact O-N 3.36Å; F336-L339 PolarHBondContact O-N 2.72Å; L339-A341 PolarHBondContact O-N 3Å; L339-S342 PolarHBondContact O-N 2.94Å; L339-I343 VanDerWaalsContact O-CG1 3.3Å; L339-I343 WeakPolarHBondContact O-CG1 3.39Å; L339-I343 PolarHBondContact O-N 2.76Å
340	Y	87.6	Confident	78.2	Confident	33 Å²	33	40.6 Å²	40.6	13%	0.129	23%	0.226	C	C	.	.	H	α-helix	trans	-59.5	-47	176.4	-176.4	-111.8	0	0	0	111.8	L176 F180 F336 C337 T338 S342 R344	L176-Y340 HydrophobicContact CB-CD1 4.36Å; L176-Y340 HydrophobicContact CD2-CD1 4.26Å; L176-Y340 WeakPolarHBondContact O-CE1 3.44Å; F180-Y340 VanDerWaalsContact CA-OH 3.25Å; F180-Y340 WeakPolarHBondContact CA-OH 3.42Å; F180-Y340 HydrophobicContact CB-CD1 4.48Å; F180-Y340 HydrophobicContact CB-CE1 3.86Å; F180-Y340 HydrophobicContact CB-CE2 4.24Å; F180-Y340 HydrophobicContact CD2-CD2 4.4Å; F180-Y340 AromaticContact CD2-CE2 3.94Å; F180-Y340 HydrophobicContact CD2-CE2 3.94Å; F180-Y340 PolarHBondContact N-OH 3.05Å; F336-Y340 VanDerWaalsContact O-CB 3.24Å; F336-Y340 WeakPolarHBondContact O-CB 3.37Å; F336-Y340 PolarHBondContact O-N 2.95Å; C337-Y340 PolarHBondContact O-N 3.21Å; T338-Y340 VanDerWaalsContact C-N 3.34Å; Y340-S342 PolarHBondContact O-N 2.98Å; Y340-R344 VanDerWaalsContact CZ-NH1 3.32Å; Y340-R344 WeakPolarHBondContact O-CB 3.46Å; Y340-R344 PolarHBondContact O-N 3.13Å; Y340-R344 VanDerWaalsContact OH-CD 3.3Å; Y340-R344 WeakPolarHBondContact OH-CD 3.38Å; Y340-R344 PolarHBondContact OH-NE 3.43Å; Y340-R344 PolarHBondContact OH-NH1 3.42Å
341	A	85.1	Confident	76.6	Confident	17 Å²	17	41.2 Å²	41.2	14%	0.14	23%	0.23	C	C	.	.	H	α-helix	trans	-60.7	-31.1	176.7	0	0	0	0	0	113.2	R39 L176 C337 T338 L339	R39-A341 PolarHBondContact NH1-O 3.22Å; R39-A341 VanDerWaalsContact NH1-O 3.16Å; L176-A341 HydrophobicContact CD1-CB 3.96Å; L176-A341 HydrophobicContact CD2-CB 4.22Å; C337-A341 WeakPolarHBondContact O-CB 3.4Å; C337-A341 PolarHBondContact O-N 3.41Å; T338-A341 PolarHBondContact O-N 3.34Å; L339-A341 PolarHBondContact O-N 3Å
342	S	83.3	Confident	75	Confident	1 Å²	1	40.5 Å²	40.5	1%	0.007	23%	0.226	C	C	.	.	H	α-helix	trans	-87.7	-32.7	-175.8	-63.8	0	0	0	0	114.1	R39 S43 T338 L339 Y340	R39-S342 PolarHBondContact NE-O 3.45Å; R39-S342 PolarHBondContact NH2-O 3.3Å; S43-S342 WeakPolarHBondContact OG-CB 3.49Å; S43-S342 PolarHBondContact OG-OG 2.9Å; T338-S342 WeakPolarHBondContact O-CB 3.41Å; T338-S342 PolarHBondContact O-N 2.83Å; T338-S342 VanDerWaalsContact O-N 3.15Å; T338-S342 PolarHBondContact O-OG 2.86Å; T338-S342 VanDerWaalsContact O-OG 3.06Å; L339-S342 PolarHBondContact O-N 2.94Å; Y340-S342 PolarHBondContact O-N 2.98Å
343	I	79.8	Confident	73.4	Confident	105 Å²	105	43.2 Å²	43.2	54%	0.538	23%	0.23	S	C	.	.	H	α-helix	trans	-79.1	-37.7	176.4	-65.3	166.9	0	0	0	110.1	L40 L339 S345	L40-I343 HydrophobicContact CD2-CG1 3.94Å; L339-I343 VanDerWaalsContact O-CG1 3.3Å; L339-I343 WeakPolarHBondContact O-CG1 3.39Å; L339-I343 PolarHBondContact O-N 2.76Å; I343-S345 PolarHBondContact O-N 3.05Å
344	R	71	Confident	71.5	Confident	33 Å²	33	46.4 Å²	46.4	13%	0.125	25%	0.247	C	C	.	.			trans	-73.7	121.2	-167.8	-173.3	166.3	177.9	-147.2	-1.2	112.6	R39 D179 Y340 S346	R39-R344 PolarHBondContact NH1-O 2.7Å; R39-R344 PolarHBondContact NH2-O 3.3Å; D179-R344 IonicContact OD1-CZ 3.62Å; D179-R344 IonicContact OD1-NH1 3.5Å; D179-R344 IonicContact OD1-NH2 3.76Å; D179-R344 PolarHBondContact OD1-NH2 3.37Å; D179-R344 IonicContact OD2-CZ 3.89Å; D179-R344 IonicContact OD2-NH1 3Å; D179-R344 PolarHBondContact OD2-NH1 3.31Å; D179-R344 IonicContact OD2-NH2 2.86Å; D179-R344 PolarHBondContact OD2-NH2 3.3Å; Y340-R344 VanDerWaalsContact CZ-NH1 3.32Å; Y340-R344 WeakPolarHBondContact O-CB 3.46Å; Y340-R344 PolarHBondContact O-N 3.13Å; Y340-R344 VanDerWaalsContact OH-CD 3.3Å; Y340-R344 WeakPolarHBondContact OH-CD 3.38Å; Y340-R344 PolarHBondContact OH-NE 3.43Å; Y340-R344 PolarHBondContact OH-NH1 3.42Å; R344-S346 PolarHBondContact NH2-OG 2.92Å
345	S	56.5	Low	69.6	Low	82 Å²	82	47 Å²	47	57%	0.573	25%	0.25	S	S	*	.			trans	-97.7	108.6	152.7	-171.1	0	0	0	0	104.4	I343	I343-S345 PolarHBondContact O-N 3.05Å
346	S	48	Very low	67.8	Low	28 Å²	28	49.5 Å²	49.5	20%	0.196	26%	0.26	C	S	.	.			trans	-88.2	138.1	-155.3	159.4	0	0	0	0	114	R344 N348 N352	R344-S346 PolarHBondContact NH2-OG 2.92Å; S346-N348 PolarHBondContact OG-N 3.24Å; S346-N352 WeakPolarHBondContact CB-OD1 3.3Å; S346-N352 PolarHBondContact O-ND2 3.12Å; S346-N352 PolarHBondContact OG-ND2 3.2Å; S346-N352 PolarHBondContact OG-OD1 3.2Å
347	T	45.6	Very low	65.7	Low	99 Å²	99	47.8 Å²	47.8	61%	0.607	26%	0.256	S	S	*	.	S	Bend	trans	-89	1.3	176.9	54.2	0	0	0	0	115.6
348	N	51.3	Low	63.4	Low	41 Å²	41	52.2 Å²	52.2	22%	0.219	28%	0.277	C	S	.	.			trans	-110.6	106	-179	-89.8	-46.7	0	0	0	110.6	D179 S346 Q350 V351 N352	D179-N348 VanDerWaalsContact OD1-CB 3.31Å; D179-N348 WeakPolarHBondContact OD1-CB 3.41Å; D179-N348 PolarHBondContact OD1-ND2 3.19Å; S346-N348 PolarHBondContact OG-N 3.24Å; N348-Q350 PolarHBondContact O-N 3Å; N348-V351 PolarHBondContact O-N 3.09Å; N348-N352 WeakPolarHBondContact O-CB 3.17Å; N348-N352 PolarHBondContact O-N 2.9Å; N348-N352 PolarHBondContact O-ND2 3.19Å; N348-N352 PolarHBondContact O-OD1 3.4Å
349	A	54.3	Low	61.4	Low	19 Å²	19	57.3 Å²	57.3	16%	0.157	30%	0.3	C	S	.	.	H	α-helix	trans	-63.8	-36.8	-173.3	0	0	0	0	0	113.8	V351 N352 K353 E358 N457	A349-V351 PolarHBondContact O-N 3.2Å; A349-N352 WeakPolarHBondContact O-CB 3.42Å; A349-N352 PolarHBondContact O-N 2.99Å; A349-K353 WeakPolarHBondContact O-CB 3.28Å; A349-K353 PolarHBondContact O-N 3.44Å; A349-E358 VanDerWaalsContact CA-OE1 3.27Å; A349-E358 WeakPolarHBondContact CA-OE1 3.34Å; A349-N457 WeakPolarHBondContact CB-O 3.48Å; A349-N457 WeakPolarHBondContact CB-OXT 3.39Å
350	Q	54.5	Low	59.2	Low	44 Å²	44	55.8 Å²	55.8	21%	0.206	30%	0.302	C	S	.	.	H	α-helix	trans	-66.2	-39.7	-177.9	-172.7	172.8	-34.3	0	0	113.1	N348 L354 F456	N348-Q350 PolarHBondContact O-N 3Å; Q350-L354 PolarHBondContact O-N 3.04Å; Q350-F456 HydrophobicContact CG-CD1 4.44Å
351	V	58.3	Low	56.8	Low	13 Å²	13	61.4 Å²	61.4	8%	0.079	34%	0.34	C	S	.	.	H	α-helix	trans	-77.3	-32.9	175.7	178.5	0	0	0	0	110.6	I175 D179 N348 A349 K353 L354 M355	I175-V351 HydrophobicContact CG2-CG1 3.41Å; I175-V351 VanDerWaalsContact CG2-CG1 3.41Å; D179-V351 HydrophobicContact CB-CB 4.15Å; D179-V351 HydrophobicContact CB-CG1 3.83Å; D179-V351 HydrophobicContact CB-CG2 3.94Å; D179-V351 WeakPolarHBondContact OD2-CB 3.26Å; D179-V351 WeakPolarHBondContact OD2-CG1 3.48Å; N348-V351 PolarHBondContact O-N 3.09Å; A349-V351 PolarHBondContact O-N 3.2Å; V351-K353 VanDerWaalsContact C-N 3.34Å; V351-K353 PolarHBondContact O-N 2.02Å; V351-L354 CarbonylContact O-C 3.45Å; V351-L354 WeakPolarHBondContact O-CB 3.46Å; V351-L354 PolarHBondContact O-N 3.36Å; V351-L354 VanDerWaalsContact O-N 3.12Å; V351-M355 HydrophobicContact CG1-CG 4Å; V351-M355 VanDerWaalsContact O-CB 3.32Å; V351-M355 WeakPolarHBondContact O-CB 2.88Å; V351-M355 WeakPolarHBondContact O-CG 3.4Å; V351-M355 PolarHBondContact O-N 3.43Å
352	N	59.5	Low	54.7	Low	8 Å²	8	62.5 Å²	62.5	4%	0.043	35%	0.353	C	S	.	.	H	α-helix	trans	-60.7	-43.2	174.2	-72.7	-16.6	0	0	0	113	S346 N348 A349 L354 M355 Q356 T357 E358	S346-N352 WeakPolarHBondContact CB-OD1 3.3Å; S346-N352 PolarHBondContact O-ND2 3.12Å; S346-N352 PolarHBondContact OG-ND2 3.2Å; S346-N352 PolarHBondContact OG-OD1 3.2Å; N348-N352 WeakPolarHBondContact O-CB 3.17Å; N348-N352 PolarHBondContact O-N 2.9Å; N348-N352 PolarHBondContact O-ND2 3.19Å; N348-N352 PolarHBondContact O-OD1 3.4Å; A349-N352 WeakPolarHBondContact O-CB 3.42Å; A349-N352 PolarHBondContact O-N 2.99Å; N352-L354 VanDerWaalsContact C-N 3.25Å; N352-L354 PolarHBondContact O-N 3.17Å; N352-M355 CarbonylContact O-C 3.57Å; N352-M355 PolarHBondContact O-N 3.38Å; N352-Q356 WeakPolarHBondContact O-CA 2.99Å; N352-Q356 PolarHBondContact O-N 2.99Å; N352-T357 VanDerWaalsContact CA-OG1 3.24Å; N352-T357 WeakPolarHBondContact CA-OG1 3.2Å; N352-T357 PolarHBondContact O-N 3.43Å; N352-T357 PolarHBondContact O-OG1 3.17Å; N352-T357 PolarHBondContact OD1-OG1 3.45Å; N352-E358 HydrophobicContact CB-CB 4.19Å; N352-E358 HydrophobicContact CB-CG 3.72Å; N352-E358 WeakPolarHBondContact CB-OE1 3.32Å; N352-E358 PolarHBondContact ND2-OE1 2.97Å
353	K	60.3	Low	52.4	Low	145 Å²	145	67.6 Å²	67.6	63%	0.63	39%	0.388	S	S	*	.	H	α-helix	trans	-62.1	-36.6	175.2	-167.3	170.8	-170.9	165.5	0	111.8	A349 V351	A349-K353 WeakPolarHBondContact O-CB 3.28Å; A349-K353 PolarHBondContact O-N 3.44Å; V351-K353 VanDerWaalsContact C-N 3.34Å; V351-K353 PolarHBondContact O-N 2.02Å
354	L	53.8	Low	50.3	Low	95 Å²	95	66.1 Å²	66.1	50%	0.497	40%	0.399	S	S	.	.	H	α-helix	trans	-71.3	-34.8	176.1	-156.7	76.5	0	0	0	112	I175 Q350 V351 N352	I175-L354 HydrophobicContact CB-CD2 4.48Å; I175-L354 HydrophobicContact CD1-CD2 3.37Å; I175-L354 HydrophobicContact CD1-CG 4.21Å; I175-L354 HydrophobicContact CG1-CD2 3.67Å; I175-L354 HydrophobicContact CG2-CD2 3.95Å; Q350-L354 PolarHBondContact O-N 3.04Å; V351-L354 CarbonylContact O-C 3.45Å; V351-L354 WeakPolarHBondContact O-CB 3.46Å; V351-L354 PolarHBondContact O-N 3.36Å; V351-L354 VanDerWaalsContact O-N 3.12Å; N352-L354 VanDerWaalsContact C-N 3.25Å; N352-L354 PolarHBondContact O-N 3.17Å
355	M	54.8	Low	48.6	Very low	13 Å²	13	66.2 Å²	66.2	6%	0.064	41%	0.411	C	S	.	.	H	α-helix	trans	-93.2	1.9	-178.7	-71.5	-63.3	-67.1	0	0	113.9	I172 I175 L176 V351 N352 T357 F391	I172-M355 HydrophobicContact CG2-CE 3.5Å; I172-M355 HydrophobicContact CG2-SD 3.81Å; I175-M355 HydrophobicContact CG2-CG 3.88Å; I175-M355 HydrophobicContact CG2-SD 3.99Å; L176-M355 HydrophobicContact CD2-CE 4.12Å; L176-M355 HydrophobicContact CG-CE 4.35Å; V351-M355 HydrophobicContact CG1-CG 4Å; V351-M355 VanDerWaalsContact O-CB 3.32Å; V351-M355 WeakPolarHBondContact O-CB 2.88Å; V351-M355 WeakPolarHBondContact O-CG 3.4Å; V351-M355 PolarHBondContact O-N 3.43Å; N352-M355 CarbonylContact O-C 3.57Å; N352-M355 PolarHBondContact O-N 3.38Å; M355-T357 HydrophobicContact CB-CG2 4.09Å; M355-T357 PolarHBondContact O-N 3.03Å; M355-F391 HydrophobicContact CE-CE1 3.87Å; M355-F391 HydrophobicContact CE-CZ 4.44Å; M355-F391 WeakPolarHBondContact O-CD1 3.39Å; M355-F391 WeakPolarHBondContact O-CE1 3Å; M355-F391 HydrophobicContact SD-CE1 4.36Å; M355-F391 HydrophobicContact SD-CZ 4.45Å
356	Q	55.9	Low	47.8	Very low	115 Å²	115	70.9 Å²	70.9	54%	0.537	42%	0.423	S	S	.	.	T	Hydrogen-bonded Turn	trans	47.5	34.2	-173.4	-59.1	-176.8	-5.4	0	0	113.5	N352 E358 S388 F391	N352-Q356 WeakPolarHBondContact O-CA 2.99Å; N352-Q356 PolarHBondContact O-N 2.99Å; Q356-E358 VanDerWaalsContact C-N 3.34Å; Q356-S388 WeakPolarHBondContact O-CB 3.25Å; Q356-S388 PolarHBondContact O-N 3.13Å; Q356-F391 HydrophobicContact CB-CG 4.33Å
357	T	50	Low	47.5	Very low	41 Å²	41	71.3 Å²	71.3	25%	0.252	43%	0.432	S	S	.	.			trans	-90.1	-0.2	177.3	44.7	0	0	0	0	112.6	N352 M355	N352-T357 VanDerWaalsContact CA-OG1 3.24Å; N352-T357 WeakPolarHBondContact CA-OG1 3.2Å; N352-T357 PolarHBondContact O-N 3.43Å; N352-T357 PolarHBondContact O-OG1 3.17Å; N352-T357 PolarHBondContact OD1-OG1 3.45Å; M355-T357 HydrophobicContact CB-CG2 4.09Å; M355-T357 PolarHBondContact O-N 3.03Å
358	E	44	Very low	47.4	Very low	94 Å²	94	72.1 Å²	72.1	44%	0.439	44%	0.437	S	S	.	.			trans	-103.7	106.6	175.3	-101.2	168.8	-159.9	0	0	111.7	A349 N352 Q356	A349-E358 VanDerWaalsContact CA-OE1 3.27Å; A349-E358 WeakPolarHBondContact CA-OE1 3.34Å; N352-E358 HydrophobicContact CB-CB 4.19Å; N352-E358 HydrophobicContact CB-CG 3.72Å; N352-E358 WeakPolarHBondContact CB-OE1 3.32Å; N352-E358 PolarHBondContact ND2-OE1 2.97Å; Q356-E358 VanDerWaalsContact C-N 3.34Å
359	E	46.8	Very low	47	Very low	106 Å²	106	74.7 Å²	74.7	50%	0.495	45%	0.454	S	S	.	.	S	Bend	trans	-132.1	10.5	156.4	-74	-162	159.4	0	0	113.8	V385	E359-V385 HydrophobicContact CB-CG2 4.3Å
360	G	42.1	Very low	46.7	Very low	40 Å²	40	74.9 Å²	74.9	41%	0.412	46%	0.458	S	S	.	.			trans	175.3	149	169.4	0	0	0	0	0	115.9	G362	G360-G362 VanDerWaalsContact C-N 3.27Å; G360-G362 PolarHBondContact O-N 3.05Å
361	T	38.9	Very low	46.2	Very low	151 Å²	151	83.1 Å²	83.1	93%	0.926	49%	0.493	S	S	*	.			trans	-65.9	85.4	161.7	31.1	0	0	0	0	109.1	S363	T361-S363 PolarHBondContact O-N 3.36Å; T361-S363 VanDerWaalsContact O-N 3.14Å
362	G	39.4	Very low	45.9	Very low	40 Å²	40	88.2 Å²	88.2	41%	0.412	52%	0.52	S	S	.	.			trans	-62.7	112.2	168.3	0	0	0	0	0	109	G360 G364	G360-G362 VanDerWaalsContact C-N 3.27Å; G360-G362 PolarHBondContact O-N 3.05Å; G362-G364 PolarHBondContact O-N 2.96Å
363	S	35.5	Very low	45.3	Very low	107 Å²	107	90.6 Å²	90.6	75%	0.748	55%	0.546	S	S	*	.			trans	-54.4	125.7	175.9	-174.1	0	0	0	0	109.5	T361 G365	T361-S363 PolarHBondContact O-N 3.36Å; T361-S363 VanDerWaalsContact O-N 3.14Å; S363-G365 PolarHBondContact O-N 3.26Å
364	G	34.8	Very low	44.8	Very low	74 Å²	74	86 Å²	86	76%	0.763	53%	0.53	S	S	*	.			trans	-64.9	84	172.6	0	0	0	0	0	109.9	G362 E366	G362-G364 PolarHBondContact O-N 2.96Å; G364-E366 PolarHBondContact O-N 3.42Å
365	G	36.8	Very low	44.7	Very low	36 Å²	36	86 Å²	86	37%	0.371	53%	0.528	S	S	.	.			trans	-73.9	104.3	173.3	0	0	0	0	0	109.8	S363 G367	S363-G365 PolarHBondContact O-N 3.26Å; G365-G367 PolarHBondContact O-N 3.47Å
366	E	39.4	Very low	44.9	Very low	179 Å²	179	91 Å²	91	84%	0.836	55%	0.545	S	S	*	.			trans	-49.7	137	161	-72.3	-176.3	137.1	0	0	109.3	G364 V368	G364-E366 PolarHBondContact O-N 3.42Å; E366-V368 PolarHBondContact O-N 3.29Å
367	G	41.9	Very low	45	Very low	37 Å²	37	86.2 Å²	86.2	38%	0.381	53%	0.526	S	S	.	.			trans	-54.9	108	-174.3	0	0	0	0	0	112.1	G365 V369	G365-G367 PolarHBondContact O-N 3.47Å; G367-V369 PolarHBondContact O-N 2.93Å
368	V	42.4	Very low	45.9	Very low	117 Å²	117	86 Å²	86	71%	0.709	52%	0.524	S	S	*	.			trans	-74.1	111.6	174.8	-178.9	0	0	0	0	108.4	E366 G370	E366-V368 PolarHBondContact O-N 3.29Å; V368-G370 PolarHBondContact O-N 3.25Å
369	V	44.3	Very low	47.2	Very low	94 Å²	94	85 Å²	85	57%	0.57	52%	0.522	S	S	*	.			trans	-62.8	115.3	167.7	178	0	0	0	0	107.4	G367	G367-V369 PolarHBondContact O-N 2.93Å
370	G	47.4	Very low	48.5	Very low	24 Å²	24	81.2 Å²	81.2	25%	0.247	51%	0.505	C	S	.	.			trans	-59.3	146.6	172.6	0	0	0	0	0	110.2	V368 D372 G373	V368-G370 PolarHBondContact O-N 3.25Å; G370-D372 PolarHBondContact O-N 2.83Å; G370-G373 PolarHBondContact O-N 2.94Å
371	K	44.3	Very low	50.1	Low	217 Å²	217	79.3 Å²	79.3	94%	0.943	49%	0.485	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.3	-15	178.4	-85.1	178.8	171.1	174.3	0	114.7
372	D	51.4	Low	51.8	Low	120 Å²	120	77.2 Å²	77.2	64%	0.642	47%	0.465	S	S	*	.	T	Hydrogen-bonded Turn	trans	-100.3	4.9	-176.4	-41.3	-29.1	0	0	0	113.2	G370 V374 R376	G370-D372 PolarHBondContact O-N 2.83Å; D372-V374 VanDerWaalsContact C-N 3.27Å; D372-V374 PolarHBondContact O-N 3.45Å; D372-R376 IonicContact OD2-NH2 2.62Å
373	G	46.7	Very low	53.5	Low	57 Å²	57	83 Å²	83	59%	0.588	48%	0.482	S	S	*	.	S	Bend	trans	74.8	8.9	179.3	0	0	0	0	0	115.3	G370	G370-G373 PolarHBondContact O-N 2.94Å
374	V	51	Low	55.4	Low	50 Å²	50	82 Å²	82	30%	0.303	47%	0.468	S	S	.	.			trans	-95.2	121.2	178.6	-177	0	0	0	0	109.8	D372 R376	D372-V374 VanDerWaalsContact C-N 3.27Å; D372-V374 PolarHBondContact O-N 3.45Å; V374-R376 HydrophobicContact CG1-CG 4.31Å; V374-R376 PolarHBondContact O-N 3.48Å
375	H	50.9	Low	57.5	Low	95 Å²	95	78.4 Å²	78.4	44%	0.44	43%	0.431	S	S	.	.			trans	-67.4	118.4	169.6	-72.7	-74	0	0	0	109.6
376	R	58	Low	59.3	Low	116 Å²	116	77.5 Å²	77.5	44%	0.438	42%	0.418	S	S	.	.			trans	-114.2	146.4	176.6	-54.2	-159.4	176.1	151.4	5	109.5	L24 D372 V374	L24-R376 HydrophobicContact CD2-CB 3.86Å; L24-R376 WeakPolarHBondContact O-CD 3.38Å; L24-R376 WeakPolarHBondContact O-CG 3.38Å; D372-R376 IonicContact OD2-NH2 2.62Å; V374-R376 HydrophobicContact CG1-CG 4.31Å; V374-R376 PolarHBondContact O-N 3.48Å
377	A	59.9	Low	61.2	Low	15 Å²	15	69.2 Å²	69.2	12%	0.124	38%	0.38	C	S	.	.			trans	-60.3	137.3	169.9	0	0	0	0	0	110	L24 S32 N34	L24-A377 HydrophobicContact CD2-CB 4.31Å; L24-A377 WeakPolarHBondContact CD2-O 3.44Å; S32-A377 VanDerWaalsContact O-CA 3.22Å; S32-A377 WeakPolarHBondContact O-CA 3.48Å; S32-A377 WeakPolarHBondContact O-CB 3.46Å; N34-A377 HydrophobicContact CB-CB 4.49Å
378	V	67.9	Low	63.2	Low	36 Å²	36	68.7 Å²	68.7	22%	0.218	37%	0.37	C	S	.	.	B	Isolated β-bridge	trans	-84.9	128.5	-179.8	-178.9	0	0	0	0	108.7	S32 N34 N380	S32-V378 PolarHBondContact O-N 3.45Å; N34-V378 WeakPolarHBondContact CB-O 3.41Å; N34-V378 PolarHBondContact N-O 3.08Å; V378-N380 PolarHBondContact O-N 2.75Å
379	D	70.8	Confident	65.4	Low	75 Å²	75	63.2 Å²	63.2	40%	0.401	34%	0.336	S	S	.	.			trans	-75.6	104.7	169.2	-172.4	8.3	0	0	0	108.9	S120 E381	S120-D379 WeakPolarHBondContact CB-OD2 3.38Å; S120-D379 PolarHBondContact OG-OD2 2.97Å; D379-E381 PolarHBondContact OD1-N 3.07Å; D379-E381 VanDerWaalsContact OD1-N 3.15Å
380	N	73.8	Confident	67.6	Low	25 Å²	25	59.8 Å²	59.8	13%	0.134	32%	0.317	C	S	.	.			trans	-101.4	14.3	-178.1	69.8	-47.5	0	0	0	112.8	S35 V378	S35-N380 WeakPolarHBondContact CB-OD1 3.22Å; S35-N380 VanDerWaalsContact OG-CG 3.29Å; S35-N380 PolarHBondContact OG-ND2 3.18Å; S35-N380 PolarHBondContact OG-OD1 2.92Å; V378-N380 PolarHBondContact O-N 2.75Å
381	E	76.3	Confident	69.6	Low	0 Å²	0	60.5 Å²	60.5	0%	0	31%	0.313	C	S	.	.			trans	-124.7	19.7	-174.9	-60.5	-171.4	130.3	0	0	113.1	S120 D379 E383 N384 T386 Y389	S120-E381 WeakPolarHBondContact CB-O 3.42Å; S120-E381 PolarHBondContact N-O 2.82Å; S120-E381 PolarHBondContact OG-O 3.02Å; D379-E381 PolarHBondContact OD1-N 3.07Å; D379-E381 VanDerWaalsContact OD1-N 3.15Å; E381-E383 PolarHBondContact O-N 3.44Å; E381-N384 VanDerWaalsContact CA-O 3.31Å; E381-N384 WeakPolarHBondContact CA-O 3.41Å; E381-T386 HydrophobicContact CG-CG2 4.06Å; E381-T386 PolarHBondContact OE1-N 3.43Å; E381-T386 PolarHBondContact OE1-OG1 2.95Å; E381-Y389 WeakPolarHBondContact OE2-CE1 3.37Å; E381-Y389 PolarHBondContact OE2-OH 3.05Å
382	E	74.8	Confident	71.8	Confident	107 Å²	107	50.8 Å²	50.8	50%	0.5	27%	0.271	S	S	.	.	S	Bend	trans	-61.7	-40.3	-176.3	-171	-179.8	168.5	0	0	113.2	S120 K121	S120-E382 WeakPolarHBondContact OG-CA 3.22Å; K121-E382 WeakPolarHBondContact CE-OE1 3.38Å; K121-E382 IonicContact NZ-OE1 2.69Å; K121-E382 PolarHBondContact NZ-OE1 3.01Å
383	E	74.8	Confident	73.8	Confident	162 Å²	162	45.1 Å²	45.1	76%	0.757	24%	0.24	S	C	*	.	S	Bend	trans	-92.9	-47.5	-179.1	-64.9	-171.8	167.7	0	0	112.4	N119 E381	N119-E383 WeakPolarHBondContact CB-O 3.41Å; E381-E383 PolarHBondContact O-N 3.44Å
384	N	76.4	Confident	76.1	Confident	85 Å²	85	45.9 Å²	45.9	46%	0.455	23%	0.228	S	C	.	.	S	Bend	trans	-145.1	150.9	176.9	-73	-55.2	0	0	0	110.9	R118 E381	R118-N384 CarbonylContact O-C 3.39Å; R118-N384 VanDerWaalsContact O-CA 3.25Å; R118-N384 WeakPolarHBondContact O-CA 3.29Å; E381-N384 VanDerWaalsContact CA-O 3.31Å; E381-N384 WeakPolarHBondContact CA-O 3.41Å
385	V	77.9	Confident	78.1	Confident	0 Å²	0	43.7 Å²	43.7	0%	0	21%	0.214	C	C	.	.			trans	-67.8	142.6	172.4	-69.2	0	0	0	0	111.3	V117 R118 E359 Y387 Y389	V117-V385 HydrophobicContact CG1-CG1 4.38Å; R118-V385 PolarHBondContact O-N 2.67Å; E359-V385 HydrophobicContact CB-CG2 4.3Å; V385-Y387 VanDerWaalsContact C-N 3.3Å; V385-Y389 HydrophobicContact CB-CE1 4.11Å; V385-Y389 HydrophobicContact CG1-CD1 4.31Å; V385-Y389 HydrophobicContact CG1-CE1 3.72Å; V385-Y389 HydrophobicContact CG1-CE2 3.97Å
386	T	74.8	Confident	80.2	Confident	16 Å²	16	39.2 Å²	39.2	10%	0.098	19%	0.193	C	C	.	.	S	Bend	trans	-82.7	-10.3	178.6	55.4	0	0	0	0	113.3	S35 E381	S35-T386 WeakPolarHBondContact CB-OG1 3.42Å; E381-T386 HydrophobicContact CG-CG2 4.06Å; E381-T386 PolarHBondContact OE1-N 3.43Å; E381-T386 PolarHBondContact OE1-OG1 2.95Å
387	Y	79.4	Confident	82.1	Confident	6 Å²	6	34.1 Å²	34.1	2%	0.024	18%	0.176	C	C	.	.	S	Bend	trans	-157.7	153.5	175.7	66.1	-77.1	0	0	0	109.6	R39 Q128 V385 Y389 F392	R39-Y387 HydrophobicContact CG-CE1 3.96Å; R39-Y387 HydrophobicContact CG-CE2 3.89Å; Q128-Y387 PolarHBondContact NE2-OH 3.31Å; V385-Y387 VanDerWaalsContact C-N 3.3Å; Y387-Y389 HydrophobicContact CD1-CD1 4.37Å; Y387-Y389 HydrophobicContact CD1-CE1 4.29Å; Y387-Y389 HydrophobicContact CD2-CD1 4.04Å; Y387-Y389 AromaticContact CE1-CD1 3.87Å; Y387-Y389 HydrophobicContact CE1-CD1 3.87Å; Y387-Y389 AromaticContact CE1-CE1 3.65Å; Y387-Y389 HydrophobicContact CE1-CE1 3.65Å; Y387-Y389 AromaticContact CE2-CD1 3.53Å; Y387-Y389 HydrophobicContact CE2-CD1 3.53Å; Y387-Y389 HydrophobicContact CE2-CE1 4.18Å; Y387-Y389 HydrophobicContact CE2-CG 4.46Å; Y387-Y389 HydrophobicContact CG-CD1 4.44Å; Y387-Y389 AromaticContact CZ-CD1 3.41Å; Y387-Y389 VanDerWaalsContact CZ-CD1 3.41Å; Y387-Y389 AromaticContact CZ-CE1 3.59Å; Y387-Y389 WeakPolarHBondContact O-CD1 2.97Å; Y387-Y389 PolarHBondContact O-N 3.46Å; Y387-F392 HydrophobicContact CD2-CB 3.65Å; Y387-F392 HydrophobicContact CD2-CG 4.16Å; Y387-F392 HydrophobicContact CE2-CB 3.58Å; Y387-F392 HydrophobicContact CE2-CD1 4.04Å; Y387-F392 HydrophobicContact CE2-CD2 4.45Å; Y387-F392 AromaticContact CE2-CG 3.77Å; Y387-F392 HydrophobicContact CE2-CG 3.77Å
388	S	84.8	Confident	83.9	Confident	25 Å²	25	33.7 Å²	33.7	18%	0.175	17%	0.171	C	C	.	.			trans	-66.7	108.8	171	173.5	0	0	0	0	110.7	Q356 S390 F391 F392	Q356-S388 WeakPolarHBondContact O-CB 3.25Å; Q356-S388 PolarHBondContact O-N 3.13Å; S388-S390 VanDerWaalsContact C-N 3.27Å; S388-S390 PolarHBondContact O-N 2.64Å; S388-F391 PolarHBondContact O-N 3.38Å; S388-F391 WeakPolarHBondContact OG-CB 3.4Å; S388-F391 PolarHBondContact OG-N 3.49Å; S388-F392 PolarHBondContact O-N 3.2Å
389	Y	87.9	Confident	85.2	Confident	2 Å²	2	32 Å²	32	1%	0.008	16%	0.161	C	C	.	.	H	α-helix	trans	-57.2	-41.5	178.6	-67.3	-5.2	0	0	0	112.1	M114 V117 A125 Q128 E381 V385 Y387 F392 H393	M114-Y389 HydrophobicContact SD-CD2 4.36Å; V117-Y389 HydrophobicContact CB-CD2 3.9Å; V117-Y389 HydrophobicContact CB-CE2 4.35Å; V117-Y389 HydrophobicContact CG1-CD2 3.69Å; V117-Y389 HydrophobicContact CG1-CE2 3.62Å; V117-Y389 HydrophobicContact CG2-CD2 4.39Å; A125-Y389 HydrophobicContact CB-CE2 4.41Å; Q128-Y389 HydrophobicContact CB-CD2 4.3Å; Q128-Y389 HydrophobicContact CB-CE2 4.18Å; Q128-Y389 HydrophobicContact CG-CD2 3.81Å; Q128-Y389 HydrophobicContact CG-CE2 3.79Å; Q128-Y389 HydrophobicContact CG-CG 4.23Å; E381-Y389 WeakPolarHBondContact OE2-CE1 3.37Å; E381-Y389 PolarHBondContact OE2-OH 3.05Å; V385-Y389 HydrophobicContact CB-CE1 4.11Å; V385-Y389 HydrophobicContact CG1-CD1 4.31Å; V385-Y389 HydrophobicContact CG1-CE1 3.72Å; V385-Y389 HydrophobicContact CG1-CE2 3.97Å; Y387-Y389 HydrophobicContact CD1-CD1 4.37Å; Y387-Y389 HydrophobicContact CD1-CE1 4.29Å; Y387-Y389 HydrophobicContact CD2-CD1 4.04Å; Y387-Y389 AromaticContact CE1-CD1 3.87Å; Y387-Y389 HydrophobicContact CE1-CD1 3.87Å; Y387-Y389 AromaticContact CE1-CE1 3.65Å; Y387-Y389 HydrophobicContact CE1-CE1 3.65Å; Y387-Y389 AromaticContact CE2-CD1 3.53Å; Y387-Y389 HydrophobicContact CE2-CD1 3.53Å; Y387-Y389 HydrophobicContact CE2-CE1 4.18Å; Y387-Y389 HydrophobicContact CE2-CG 4.46Å; Y387-Y389 HydrophobicContact CG-CD1 4.44Å; Y387-Y389 AromaticContact CZ-CD1 3.41Å; Y387-Y389 VanDerWaalsContact CZ-CD1 3.41Å; Y387-Y389 AromaticContact CZ-CE1 3.59Å; Y387-Y389 WeakPolarHBondContact O-CD1 2.97Å; Y387-Y389 PolarHBondContact O-N 3.46Å; Y389-F392 PolarHBondContact O-N 3.08Å; Y389-H393 PolarHBondContact O-CD2 3.34Å; Y389-H393 PolarHBondContact O-N 3.29Å; Y389-H393 VanDerWaalsContact O-N 3.16Å
390	S	89.8	Confident	86.5	Confident	22 Å²	22	28.4 Å²	28.4	15%	0.154	14%	0.142	C	C	.	.	H	α-helix	trans	-63.8	-44.4	179.2	-175.4	0	0	0	0	111.7	S111 S388 H393 F394	S111-S390 WeakPolarHBondContact O-CB 3.41Å; S111-S390 PolarHBondContact O-OG 2.83Å; S111-S390 PolarHBondContact OG-O 3.47Å; S111-S390 PolarHBondContact OG-OG 3.45Å; S388-S390 VanDerWaalsContact C-N 3.27Å; S388-S390 PolarHBondContact O-N 2.64Å; S390-H393 PolarHBondContact O-N 3.39Å; S390-F394 WeakPolarHBondContact O-CB 3.32Å; S390-F394 PolarHBondContact O-N 3.45Å
391	F	89.9	Confident	87.6	Confident	39 Å²	39	27.9 Å²	27.9	17%	0.171	14%	0.139	C	C	.	.	H	α-helix	trans	-66.9	-39.5	179.1	-174.6	-95.4	0	0	0	111.9	I172 M355 Q356 S388 H393 F394 H395	I172-F391 HydrophobicContact CD1-CZ 4.45Å; M355-F391 HydrophobicContact CE-CE1 3.87Å; M355-F391 HydrophobicContact CE-CZ 4.44Å; M355-F391 WeakPolarHBondContact O-CD1 3.39Å; M355-F391 WeakPolarHBondContact O-CE1 3Å; M355-F391 HydrophobicContact SD-CE1 4.36Å; M355-F391 HydrophobicContact SD-CZ 4.45Å; Q356-F391 HydrophobicContact CB-CG 4.33Å; S388-F391 PolarHBondContact O-N 3.38Å; S388-F391 WeakPolarHBondContact OG-CB 3.4Å; S388-F391 PolarHBondContact OG-N 3.49Å; F391-H393 PolarHBondContact O-N 2.86Å; F391-F394 WeakPolarHBondContact O-CB 3.15Å; F391-F394 PolarHBondContact O-N 3.43Å; F391-H395 WeakPolarHBondContact O-CB 3.42Å; F391-H395 PolarHBondContact O-N 3.15Å
392	F	90.6	Very high	88.5	Confident	14 Å²	14	28.2 Å²	28.2	6%	0.061	14%	0.14	C	C	.	.	H	α-helix	trans	-59.9	-46.7	175.5	174.1	-101.2	0	0	0	112.3	R39 F42 Y387 S388 Y389 F394 H395 L396	R39-F392 HydrophobicContact CB-CE1 4.25Å; R39-F392 HydrophobicContact CB-CE2 3.89Å; R39-F392 HydrophobicContact CB-CZ 3.63Å; R39-F392 HydrophobicContact CG-CD1 4.31Å; R39-F392 HydrophobicContact CG-CD2 4.09Å; R39-F392 HydrophobicContact CG-CE1 3.98Å; R39-F392 HydrophobicContact CG-CE2 3.74Å; R39-F392 HydrophobicContact CG-CG 4.36Å; R39-F392 HydrophobicContact CG-CZ 3.69Å; F42-F392 HydrophobicContact CB-CE1 3.88Å; F42-F392 HydrophobicContact CB-CZ 4.36Å; F42-F392 HydrophobicContact CD2-CE1 4.45Å; F42-F392 HydrophobicContact CG-CE1 4.47Å; Y387-F392 HydrophobicContact CD2-CB 3.65Å; Y387-F392 HydrophobicContact CD2-CG 4.16Å; Y387-F392 HydrophobicContact CE2-CB 3.58Å; Y387-F392 HydrophobicContact CE2-CD1 4.04Å; Y387-F392 HydrophobicContact CE2-CD2 4.45Å; Y387-F392 AromaticContact CE2-CG 3.77Å; Y387-F392 HydrophobicContact CE2-CG 3.77Å; S388-F392 PolarHBondContact O-N 3.2Å; Y389-F392 PolarHBondContact O-N 3.08Å; F392-F394 VanDerWaalsContact C-N 3.34Å; F392-F394 PolarHBondContact O-N 2.62Å; F392-H395 WeakPolarHBondContact O-CB 3.41Å; F392-H395 PolarHBondContact O-N 2.96Å; F392-L396 HydrophobicContact CD1-CD1 4.23Å; F392-L396 HydrophobicContact CE1-CD1 3.53Å; F392-L396 HydrophobicContact CE1-CG 4.29Å; F392-L396 HydrophobicContact CE2-CD1 4.47Å; F392-L396 HydrophobicContact CZ-CD1 3.66Å; F392-L396 HydrophobicContact CZ-CD2 4.41Å; F392-L396 HydrophobicContact CZ-CG 4.18Å; F392-L396 PolarHBondContact O-N 2.87Å
393	H	94.1	Very high	89.5	Confident	0 Å²	0	23.1 Å²	23.1	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-66.4	-36.6	175.5	-74.8	-57.1	0	0	0	112.6	F42 F110 Q128 Y389 S390 F391 H395 L396 C397	F42-H393 AromaticContact CD1-CE1 3.68Å; F42-H393 AromaticContact CD2-CE1 3.66Å; F42-H393 AromaticContact CE1-CE1 3.53Å; F42-H393 AromaticContact CE2-CE1 3.52Å; F42-H393 AromaticContact CE2-NE2 3.96Å; F42-H393 AromaticContact CG-CE1 3.74Å; F42-H393 AromaticContact CZ-CE1 3.45Å; F42-H393 VanDerWaalsContact CZ-CE1 3.45Å; F42-H393 WeakPolarHBondContact CZ-CE1 3.22Å; F42-H393 AromaticContact CZ-NE2 3.98Å; F110-H393 HydrophobicContact CB-CB 4.32Å; Q128-H393 PolarHBondContact NE2-NE2 3.46Å; Q128-H393 PolarHBondContact OE1-NE2 2.91Å; Y389-H393 PolarHBondContact O-CD2 3.34Å; Y389-H393 PolarHBondContact O-N 3.29Å; Y389-H393 VanDerWaalsContact O-N 3.16Å; S390-H393 PolarHBondContact O-N 3.39Å; F391-H393 PolarHBondContact O-N 2.86Å; H393-H395 VanDerWaalsContact C-N 3.31Å; H393-H395 PolarHBondContact O-N 3.49Å; H393-L396 PolarHBondContact O-N 3.02Å; H393-C397 PolarHBondContact O-N 2.96Å
394	F	94.6	Very high	90.5	Very high	73 Å²	73	15.4 Å²	15.4	32%	0.32	8%	0.08	S	C	.	.	H	α-helix	trans	-62.1	-41.4	173.5	-175.6	-111.7	0	0	0	111.4	S390 F391 F392 L396 C397 L398	S390-F394 WeakPolarHBondContact O-CB 3.32Å; S390-F394 PolarHBondContact O-N 3.45Å; F391-F394 WeakPolarHBondContact O-CB 3.15Å; F391-F394 PolarHBondContact O-N 3.43Å; F392-F394 VanDerWaalsContact C-N 3.34Å; F392-F394 PolarHBondContact O-N 2.62Å; F394-L396 PolarHBondContact O-N 3.13Å; F394-C397 WeakPolarHBondContact O-CB 3.46Å; F394-C397 PolarHBondContact O-N 3.11Å; F394-L398 HydrophobicContact CD1-CD1 3.94Å; F394-L398 HydrophobicContact CD1-CG 4.41Å; F394-L398 HydrophobicContact CE1-CD1 3.59Å; F394-L398 HydrophobicContact CE1-CD2 4.43Å; F394-L398 HydrophobicContact CE1-CG 4.11Å; F394-L398 HydrophobicContact CZ-CD1 4.12Å; F394-L398 HydrophobicContact CZ-CD2 4.12Å; F394-L398 HydrophobicContact CZ-CG 4.21Å; F394-L398 WeakPolarHBondContact O-CG 3.41Å; F394-L398 PolarHBondContact O-N 3.15Å
395	H	93.1	Very high	91.3	Very high	5 Å²	5	11.3 Å²	11.3	2%	0.023	6%	0.058	C	C	.	.	H	α-helix	trans	-58.9	-46.2	173.2	171.6	72.5	0	0	0	111.9	F169 I172 F391 F392 H393 C397 L398 A399	F169-H395 AromaticContact CE2-CE1 3.46Å; F169-H395 VanDerWaalsContact CE2-CE1 3.46Å; F169-H395 WeakPolarHBondContact CE2-CE1 3.27Å; F169-H395 AromaticContact CE2-NE2 4Å; I172-H395 WeakPolarHBondContact CG2-ND1 3.42Å; F391-H395 WeakPolarHBondContact O-CB 3.42Å; F391-H395 PolarHBondContact O-N 3.15Å; F392-H395 WeakPolarHBondContact O-CB 3.41Å; F392-H395 PolarHBondContact O-N 2.96Å; H393-H395 VanDerWaalsContact C-N 3.31Å; H393-H395 PolarHBondContact O-N 3.49Å; H395-C397 VanDerWaalsContact C-N 3.31Å; H395-C397 PolarHBondContact O-N 3.18Å; H395-L398 PolarHBondContact O-N 2.88Å; H395-A399 WeakPolarHBondContact O-CB 3.25Å; H395-A399 PolarHBondContact O-N 3.32Å
396	L	95.1	Very high	92	Very high	0 Å²	0	11.7 Å²	11.7	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-65.5	-32.5	176.1	-63.1	-179.4	0	0	0	112.9	F42 L46 F107 T338 F392 H393 F394 A399 S400	F42-L396 HydrophobicContact CB-CD1 3.77Å; L46-L396 HydrophobicContact CD2-CD2 3.71Å; F107-L396 HydrophobicContact CB-CB 4.3Å; F107-L396 HydrophobicContact CD1-CB 3.62Å; F107-L396 HydrophobicContact CD1-CD1 3.81Å; F107-L396 HydrophobicContact CD1-CG 4.4Å; F107-L396 HydrophobicContact CD2-CB 4.04Å; F107-L396 HydrophobicContact CE1-CB 3.89Å; F107-L396 HydrophobicContact CE1-CD1 3.49Å; F107-L396 VanDerWaalsContact CE1-CD1 3.49Å; F107-L396 HydrophobicContact CE1-CG 4.34Å; F107-L396 HydrophobicContact CE2-CB 4.29Å; F107-L396 HydrophobicContact CG-CB 3.72Å; F107-L396 HydrophobicContact CZ-CB 4.22Å; F107-L396 HydrophobicContact CZ-CD1 4.17Å; T338-L396 HydrophobicContact CG2-CD2 4.41Å; F392-L396 HydrophobicContact CD1-CD1 4.23Å; F392-L396 HydrophobicContact CE1-CD1 3.53Å; F392-L396 HydrophobicContact CE1-CG 4.29Å; F392-L396 HydrophobicContact CE2-CD1 4.47Å; F392-L396 HydrophobicContact CZ-CD1 3.66Å; F392-L396 HydrophobicContact CZ-CD2 4.41Å; F392-L396 HydrophobicContact CZ-CG 4.18Å; F392-L396 PolarHBondContact O-N 2.87Å; H393-L396 PolarHBondContact O-N 3.02Å; F394-L396 PolarHBondContact O-N 3.13Å; L396-A399 WeakPolarHBondContact O-CB 3.31Å; L396-A399 PolarHBondContact O-N 2.75Å; L396-S400 PolarHBondContact O-N 2.96Å
397	C	97.4	Very high	92.7	Very high	10 Å²	10	11.7 Å²	11.7	7%	0.068	6%	0.06	C	C	.	.	H	α-helix	trans	-61.6	-50.7	171	178.4	0	0	0	0	110.9	A104 F107 H393 F394 H395 A399 S400 L401	A104-C397 PolarHBondContact O-SG 3.19Å; F107-C397 HydrophobicContact CB-CB 3.82Å; H393-C397 PolarHBondContact O-N 2.96Å; F394-C397 WeakPolarHBondContact O-CB 3.46Å; F394-C397 PolarHBondContact O-N 3.11Å; H395-C397 VanDerWaalsContact C-N 3.31Å; H395-C397 PolarHBondContact O-N 3.18Å; C397-A399 VanDerWaalsContact C-N 3.26Å; C397-A399 PolarHBondContact O-N 3Å; C397-S400 PolarHBondContact O-N 3.24Å; C397-S400 VanDerWaalsContact O-N 3.14Å; C397-S400 PolarHBondContact O-OG 3.16Å; C397-L401 PolarHBondContact O-N 3.49Å
398	L	97	Very high	93.1	Very high	6 Å²	6	11.4 Å²	11.4	3%	0.031	6%	0.059	C	C	.	.	H	α-helix	trans	-59.8	-38.3	175.1	-64.9	174.3	0	0	0	112.2	I168 F169 I172 F394 H395 S400 L401 Y402	I168-L398 HydrophobicContact CB-CD1 4.08Å; I168-L398 HydrophobicContact CB-CD2 4.25Å; I168-L398 HydrophobicContact CD1-CD2 4.35Å; I168-L398 HydrophobicContact CG2-CD1 3.51Å; I168-L398 HydrophobicContact CG2-CD2 4.46Å; F169-L398 HydrophobicContact CB-CB 4.13Å; F169-L398 HydrophobicContact CD2-CB 4.19Å; I172-L398 HydrophobicContact CD1-CD1 3.74Å; F394-L398 HydrophobicContact CD1-CD1 3.94Å; F394-L398 HydrophobicContact CD1-CG 4.41Å; F394-L398 HydrophobicContact CE1-CD1 3.59Å; F394-L398 HydrophobicContact CE1-CD2 4.43Å; F394-L398 HydrophobicContact CE1-CG 4.11Å; F394-L398 HydrophobicContact CZ-CD1 4.12Å; F394-L398 HydrophobicContact CZ-CD2 4.12Å; F394-L398 HydrophobicContact CZ-CG 4.21Å; F394-L398 WeakPolarHBondContact O-CG 3.41Å; F394-L398 PolarHBondContact O-N 3.15Å; H395-L398 PolarHBondContact O-N 2.88Å; L398-S400 VanDerWaalsContact C-N 3.32Å; L398-S400 PolarHBondContact O-N 3.31Å; L398-L401 WeakPolarHBondContact O-CB 3.1Å; L398-L401 PolarHBondContact O-N 2.86Å; L398-Y402 PolarHBondContact O-N 3.35Å
399	A	95.9	Very high	93.2	Very high	0 Å²	0	10.5 Å²	10.5	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-59.6	-41.8	176.2	0	0	0	0	0	111.6	L46 F169 F334 H395 L396 C397 Y402 I403	L46-A399 HydrophobicContact CD2-CB 3.62Å; F169-A399 VanDerWaalsContact CD2-CA 3.45Å; F169-A399 HydrophobicContact CD2-CB 3.85Å; F169-A399 VanDerWaalsContact CE2-CA 3.45Å; F169-A399 HydrophobicContact CE2-CB 3.35Å; F169-A399 HydrophobicContact CZ-CB 4.03Å; F334-A399 HydrophobicContact CE2-CB 3.78Å; F334-A399 HydrophobicContact CZ-CB 4.42Å; H395-A399 WeakPolarHBondContact O-CB 3.25Å; H395-A399 PolarHBondContact O-N 3.32Å; L396-A399 WeakPolarHBondContact O-CB 3.31Å; L396-A399 PolarHBondContact O-N 2.75Å; C397-A399 VanDerWaalsContact C-N 3.26Å; C397-A399 PolarHBondContact O-N 3Å; A399-Y402 PolarHBondContact O-N 2.87Å; A399-I403 WeakPolarHBondContact O-CG1 3.37Å; A399-I403 PolarHBondContact O-N 2.87Å
400	S	97.3	Very high	93.3	Very high	0 Å²	0	10.6 Å²	10.6	0%	0	5%	0.053	C	C	.	.	H	α-helix	trans	-65.6	-36.2	175.6	75	0	0	0	0	113	A104 L396 C397 L398 I403 M404	A104-S400 VanDerWaalsContact CA-OG 3.28Å; A104-S400 WeakPolarHBondContact CA-OG 3.31Å; A104-S400 WeakPolarHBondContact CB-OG 3.41Å; A104-S400 PolarHBondContact N-OG 3.49Å; L396-S400 PolarHBondContact O-N 2.96Å; C397-S400 PolarHBondContact O-N 3.24Å; C397-S400 VanDerWaalsContact O-N 3.14Å; C397-S400 PolarHBondContact O-OG 3.16Å; L398-S400 VanDerWaalsContact C-N 3.32Å; L398-S400 PolarHBondContact O-N 3.31Å; S400-I403 PolarHBondContact O-N 3.4Å; S400-M404 PolarHBondContact O-N 3.45Å
401	L	97.4	Very high	93	Very high	13 Å²	13	10.5 Å²	10.5	7%	0.068	5%	0.049	C	C	.	.	H	α-helix	trans	-67.5	-39.5	173.9	-65.6	175.5	0	0	0	111.5	A104 W158 S166 C397 L398 M404 M405	A104-L401 HydrophobicContact CB-CD2 4.18Å; A104-L401 HydrophobicContact CB-CG 4.46Å; W158-L401 HydrophobicContact CH2-CD2 4.25Å; W158-L401 HydrophobicContact CZ2-CD2 3.58Å; S166-L401 PolarHBondContact OG-O 2.56Å; C397-L401 PolarHBondContact O-N 3.49Å; L398-L401 WeakPolarHBondContact O-CB 3.1Å; L398-L401 PolarHBondContact O-N 2.86Å; L401-M404 HydrophobicContact CD2-CE 4.41Å; L401-M404 WeakPolarHBondContact O-CB 3.39Å; L401-M404 PolarHBondContact O-N 3.06Å; L401-M405 WeakPolarHBondContact O-CG 3.34Å; L401-M405 PolarHBondContact O-N 3.18Å
402	Y	96.3	Very high	92.7	Very high	7 Å²	7	11.4 Å²	11.4	3%	0.027	5%	0.054	C	C	.	.	H	α-helix	trans	-63.8	-44.1	174.3	173.3	-95.2	0	0	0	112.9	S166 F169 I170 F334 L398 A399 M404 M405 T406 W410	S166-Y402 VanDerWaalsContact OG-CA 3.32Å; S166-Y402 WeakPolarHBondContact OG-CA 3.18Å; F169-Y402 VanDerWaalsContact CD1-CB 3.44Å; F169-Y402 AromaticContact CD1-CD1 3.74Å; F169-Y402 HydrophobicContact CD1-CD1 3.74Å; F169-Y402 AromaticContact CD1-CD2 3.74Å; F169-Y402 HydrophobicContact CD1-CD2 3.74Å; F169-Y402 HydrophobicContact CD1-CE1 4.44Å; F169-Y402 HydrophobicContact CD1-CE2 4.43Å; F169-Y402 AromaticContact CD1-CG 3.33Å; F169-Y402 HydrophobicContact CD1-CG 3.33Å; F169-Y402 AromaticContact CE1-CD1 3.61Å; F169-Y402 HydrophobicContact CE1-CD1 3.61Å; F169-Y402 HydrophobicContact CE1-CD2 4.37Å; F169-Y402 HydrophobicContact CE1-CE1 4.13Å; F169-Y402 AromaticContact CE1-CG 3.74Å; F169-Y402 HydrophobicContact CE1-CG 3.74Å; F169-Y402 HydrophobicContact CG-CG 4.17Å; I170-Y402 HydrophobicContact CD1-CD2 4.42Å; I170-Y402 HydrophobicContact CD1-CE2 4.18Å; I170-Y402 HydrophobicContact CG1-CD2 4.01Å; I170-Y402 HydrophobicContact CG1-CE2 3.84Å; F334-Y402 HydrophobicContact CB-CE1 4Å; F334-Y402 AromaticContact CD2-CD1 3.8Å; F334-Y402 HydrophobicContact CD2-CD1 3.8Å; F334-Y402 HydrophobicContact CD2-CE1 4.15Å; F334-Y402 HydrophobicContact CE2-CD1 4.49Å; F334-Y402 HydrophobicContact CG-CE1 4.45Å; L398-Y402 PolarHBondContact O-N 3.35Å; A399-Y402 PolarHBondContact O-N 2.87Å; Y402-M404 VanDerWaalsContact C-N 3.31Å; Y402-M404 PolarHBondContact O-N 3.37Å; Y402-M405 PolarHBondContact O-N 3.37Å; Y402-T406 WeakPolarHBondContact CE1-OG1 3.27Å; Y402-T406 WeakPolarHBondContact O-CB 3.3Å; Y402-T406 PolarHBondContact O-N 3.25Å; Y402-T406 PolarHBondContact O-OG1 3.46Å; Y402-W410 HydrophobicContact CD2-CZ2 4.36Å; Y402-W410 HydrophobicContact CE2-CZ2 4.34Å
403	I	95.1	Very high	92	Very high	0 Å²	0	11.4 Å²	11.4	0%	0	6%	0.055	C	C	.	.	H	α-helix	trans	-60.9	-42.9	176.2	-75.6	-57.1	0	0	0	111.1	T50 L331 F334 A399 S400 M405 T406 L407	T50-I403 HydrophobicContact CG2-CD1 4.08Å; T50-I403 HydrophobicContact CG2-CG1 4.28Å; T50-I403 HydrophobicContact CG2-CG2 3.85Å; L331-I403 HydrophobicContact CD1-CD1 3.59Å; F334-I403 HydrophobicContact CB-CD1 4.43Å; F334-I403 HydrophobicContact CD1-CD1 3.62Å; F334-I403 HydrophobicContact CD1-CG1 4.26Å; F334-I403 HydrophobicContact CD2-CD1 3.75Å; F334-I403 HydrophobicContact CD2-CG1 3.93Å; F334-I403 HydrophobicContact CE1-CD1 3.66Å; F334-I403 HydrophobicContact CE1-CG1 3.82Å; F334-I403 HydrophobicContact CE2-CD1 3.74Å; F334-I403 HydrophobicContact CE2-CG1 3.41Å; F334-I403 VanDerWaalsContact CE2-CG1 3.41Å; F334-I403 HydrophobicContact CG-CD1 3.68Å; F334-I403 HydrophobicContact CG-CG1 4.31Å; F334-I403 HydrophobicContact CZ-CD1 3.7Å; F334-I403 HydrophobicContact CZ-CG1 3.36Å; A399-I403 WeakPolarHBondContact O-CG1 3.37Å; A399-I403 PolarHBondContact O-N 2.87Å; S400-I403 PolarHBondContact O-N 3.4Å; I403-M405 PolarHBondContact O-N 3.45Å; I403-T406 PolarHBondContact O-N 3.46Å; I403-L407 HydrophobicContact CG2-CD1 3.63Å; I403-L407 HydrophobicContact CG2-CG 4.07Å; I403-L407 WeakPolarHBondContact O-CB 3.2Å; I403-L407 WeakPolarHBondContact O-CG 3.29Å; I403-L407 PolarHBondContact O-N 3.4Å
404	M	94.8	Very high	90.8	Very high	0 Å²	0	13.3 Å²	13.3	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-54.1	-52.4	175.2	-174.3	-177.3	69.6	0	0	111.9	Y97 C100 W158 S400 L401 Y402 T406 T408	Y97-M404 HydrophobicContact CD1-CE 4.49Å; Y97-M404 HydrophobicContact CD1-SD 3.79Å; Y97-M404 HydrophobicContact CD2-CG 4.45Å; Y97-M404 HydrophobicContact CE1-CE 4.18Å; Y97-M404 HydrophobicContact CE1-SD 4.03Å; Y97-M404 HydrophobicContact CG-CG 4.39Å; Y97-M404 HydrophobicContact CG-SD 4.1Å; C100-M404 HydrophobicContact CB-CB 3.55Å; C100-M404 HydrophobicContact CB-CG 3.89Å; C100-M404 HydrophobicContact CB-SD 4.17Å; W158-M404 HydrophobicContact CG-CE 4.46Å; W158-M404 HydrophobicContact CG-SD 4.29Å; W158-M404 PolarHBondContact NE1-SD 3.15Å; S400-M404 PolarHBondContact O-N 3.45Å; L401-M404 HydrophobicContact CD2-CE 4.41Å; L401-M404 WeakPolarHBondContact O-CB 3.39Å; L401-M404 PolarHBondContact O-N 3.06Å; Y402-M404 VanDerWaalsContact C-N 3.31Å; Y402-M404 PolarHBondContact O-N 3.37Å; M404-T406 VanDerWaalsContact C-N 3.34Å; M404-T406 PolarHBondContact O-N 2.93Å; M404-T408 WeakPolarHBondContact O-CB 3.48Å; M404-T408 VanDerWaalsContact O-CG2 3.27Å; M404-T408 WeakPolarHBondContact O-CG2 3.32Å; M404-T408 PolarHBondContact O-N 2.89Å; M404-T408 VanDerWaalsContact O-N 3.15Å; M404-T408 PolarHBondContact O-OG1 3.34Å
405	M	93.7	Very high	89.3	Confident	0 Å²	0	14.5 Å²	14.5	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-65.5	-39.6	-178.6	-62.6	-57.2	-66.2	0	0	111.4	F159 L163 S166 L401 Y402 I403 T408 N409 W410	F159-M405 HydrophobicContact CD2-CE 3.49Å; F159-M405 VanDerWaalsContact CD2-CE 3.49Å; F159-M405 HydrophobicContact CD2-SD 4.14Å; F159-M405 HydrophobicContact CE2-CE 3.4Å; F159-M405 VanDerWaalsContact CE2-CE 3.4Å; F159-M405 HydrophobicContact CG-CE 4.4Å; F159-M405 HydrophobicContact CZ-CE 4.25Å; L163-M405 HydrophobicContact CD2-CE 3.66Å; L163-M405 HydrophobicContact CG-CE 3.91Å; S166-M405 VanDerWaalsContact OG-CG 3.22Å; S166-M405 WeakPolarHBondContact OG-CG 3.18Å; L401-M405 WeakPolarHBondContact O-CG 3.34Å; L401-M405 PolarHBondContact O-N 3.18Å; Y402-M405 PolarHBondContact O-N 3.37Å; I403-M405 PolarHBondContact O-N 3.45Å; M405-T408 PolarHBondContact O-N 3.47Å; M405-T408 PolarHBondContact O-OG1 3.45Å; M405-N409 PolarHBondContact O-N 3.48Å; M405-W410 HydrophobicContact CB-CD2 3.86Å; M405-W410 HydrophobicContact CB-CE3 4.32Å; M405-W410 HydrophobicContact CB-CG 4.23Å; M405-W410 HydrophobicContact CB-CZ2 4.04Å; M405-W410 HydrophobicContact CE-CD2 4.23Å; M405-W410 HydrophobicContact CE-CE3 3.9Å; M405-W410 PolarHBondContact O-N 2.97Å
406	T	92.7	Very high	87.6	Confident	7 Å²	7	19.8 Å²	19.8	4%	0.043	11%	0.111	C	C	.	.	H	α-helix	trans	-66.4	-47	-179.7	-59	0	0	0	0	112.1	Y402 I403 M404 T408 N409	Y402-T406 WeakPolarHBondContact CE1-OG1 3.27Å; Y402-T406 WeakPolarHBondContact O-CB 3.3Å; Y402-T406 PolarHBondContact O-N 3.25Å; Y402-T406 PolarHBondContact O-OG1 3.46Å; I403-T406 PolarHBondContact O-N 3.46Å; M404-T406 VanDerWaalsContact C-N 3.34Å; M404-T406 PolarHBondContact O-N 2.93Å; T406-T408 PolarHBondContact O-N 2.89Å; T406-N409 PolarHBondContact O-N 2.92Å
407	L	90.2	Very high	85.8	Confident	16 Å²	16	23 Å²	23	8%	0.084	13%	0.131	C	C	.	.	H	α-helix	trans	-69.4	-23.2	179.6	-69.2	-177.3	0	0	0	113	V54 I57 Y93 V96 I403 N409	V54-L407 HydrophobicContact CG2-CD1 4.16Å; V54-L407 HydrophobicContact CG2-CD2 3.79Å; I57-L407 HydrophobicContact CD1-CB 3.89Å; I57-L407 VanDerWaalsContact CD1-O 3.31Å; I57-L407 WeakPolarHBondContact CD1-O 3.46Å; Y93-L407 WeakPolarHBondContact CE1-O 3.2Å; V96-L407 HydrophobicContact CG1-CB 4.03Å; V96-L407 HydrophobicContact CG1-CD1 4.19Å; I403-L407 HydrophobicContact CG2-CD1 3.63Å; I403-L407 HydrophobicContact CG2-CG 4.07Å; I403-L407 WeakPolarHBondContact O-CB 3.2Å; I403-L407 WeakPolarHBondContact O-CG 3.29Å; I403-L407 PolarHBondContact O-N 3.4Å; L407-N409 VanDerWaalsContact C-N 3.32Å
408	T	87.7	Confident	84	Confident	1 Å²	1	25.1 Å²	25.1	1%	0.006	14%	0.14	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97	16.1	176.9	59.5	0	0	0	0	112.5	Y93 V96 Y97 M404 M405 T406 W410 Y411	Y93-T408 HydrophobicContact CD1-CG2 4.05Å; Y93-T408 HydrophobicContact CG-CG2 4.01Å; V96-T408 HydrophobicContact CB-CG2 4.31Å; V96-T408 HydrophobicContact CG1-CG2 4.08Å; Y97-T408 HydrophobicContact CD2-CG2 3.88Å; Y97-T408 HydrophobicContact CE2-CG2 3.64Å; M404-T408 WeakPolarHBondContact O-CB 3.48Å; M404-T408 VanDerWaalsContact O-CG2 3.27Å; M404-T408 WeakPolarHBondContact O-CG2 3.32Å; M404-T408 PolarHBondContact O-N 2.89Å; M404-T408 VanDerWaalsContact O-N 3.15Å; M404-T408 PolarHBondContact O-OG1 3.34Å; M405-T408 PolarHBondContact O-N 3.47Å; M405-T408 PolarHBondContact O-OG1 3.45Å; T406-T408 PolarHBondContact O-N 2.89Å; T408-W410 PolarHBondContact O-N 2.82Å; T408-Y411 PolarHBondContact O-N 3.44Å
409	N	86.3	Confident	82.3	Confident	6 Å²	6	26.3 Å²	26.3	3%	0.032	15%	0.151	C	C	.	.	T	Hydrogen-bonded Turn	trans	52.5	24.7	179.9	-69.9	-44.4	0	0	0	114.2	Y93 N287 Q326 M405 T406 L407 Y411	Y93-N409 PolarHBondContact OH-ND2 3.34Å; N287-N409 PolarHBondContact ND2-O 3.49Å; Q326-N409 PolarHBondContact NE2-OD1 2.78Å; M405-N409 PolarHBondContact O-N 3.48Å; T406-N409 PolarHBondContact O-N 2.92Å; L407-N409 VanDerWaalsContact C-N 3.32Å; N409-Y411 HydrophobicContact CB-CD2 3.87Å; N409-Y411 HydrophobicContact CB-CE1 4.32Å; N409-Y411 HydrophobicContact CB-CE2 3.67Å; N409-Y411 HydrophobicContact CB-CG 4.32Å; N409-Y411 PolarHBondContact O-N 3.29Å
410	W	89.5	Confident	81	Confident	4 Å²	4	28 Å²	28	2%	0.015	16%	0.159	C	C	.	.	T	Hydrogen-bonded Turn	trans	56.5	24.7	-176.2	-64	65.1	0	0	0	113.9	L163 I170 Y402 M405 T408 A426 V429 K430	L163-W410 HydrophobicContact CD2-CE3 3.61Å; L163-W410 HydrophobicContact CD2-CZ3 3.6Å; I170-W410 HydrophobicContact CD1-CH2 3.99Å; I170-W410 HydrophobicContact CD1-CZ2 4.14Å; Y402-W410 HydrophobicContact CD2-CZ2 4.36Å; Y402-W410 HydrophobicContact CE2-CZ2 4.34Å; M405-W410 HydrophobicContact CB-CD2 3.86Å; M405-W410 HydrophobicContact CB-CE3 4.32Å; M405-W410 HydrophobicContact CB-CG 4.23Å; M405-W410 HydrophobicContact CB-CZ2 4.04Å; M405-W410 HydrophobicContact CE-CD2 4.23Å; M405-W410 HydrophobicContact CE-CE3 3.9Å; M405-W410 PolarHBondContact O-N 2.97Å; T408-W410 PolarHBondContact O-N 2.82Å; W410-A426 HydrophobicContact CB-CB 3.92Å; W410-A426 HydrophobicContact CD2-CB 4.48Å; W410-A426 HydrophobicContact CE3-CB 3.82Å; W410-V429 HydrophobicContact CH2-CG1 4.02Å; W410-V429 HydrophobicContact CZ3-CB 4.37Å; W410-V429 HydrophobicContact CZ3-CG1 3.8Å; W410-K430 HydrophobicContact CH2-CG 4.35Å
411	Y	85.3	Confident	79.8	Confident	20 Å²	20	32.7 Å²	32.7	8%	0.078	18%	0.181	C	C	.	.	P	Polyproline II helix	trans	-76.1	139.5	176.9	-65	-34.4	0	0	0	111.5	Y93 F159 T408 N409 M420 Q421 S422	Y93-Y411 AromaticContact CE2-CD2 3.89Å; Y93-Y411 HydrophobicContact CE2-CD2 3.89Å; Y93-Y411 HydrophobicContact CE2-CE2 4.47Å; F159-Y411 WeakPolarHBondContact CD2-O 3.37Å; F159-Y411 WeakPolarHBondContact CE2-O 3.32Å; T408-Y411 PolarHBondContact O-N 3.44Å; N409-Y411 HydrophobicContact CB-CD2 3.87Å; N409-Y411 HydrophobicContact CB-CE1 4.32Å; N409-Y411 HydrophobicContact CB-CE2 3.67Å; N409-Y411 HydrophobicContact CB-CG 4.32Å; N409-Y411 PolarHBondContact O-N 3.29Å; Y411-M420 HydrophobicContact CD2-CB 3.88Å; Y411-M420 HydrophobicContact CG-CB 4.12Å; Y411-Q421 VanDerWaalsContact CA-O 3.29Å; Y411-Q421 WeakPolarHBondContact CA-O 3.42Å; Y411-S422 WeakPolarHBondContact CE1-OG 3.35Å
412	Q	83	Confident	79	Confident	57 Å²	57	32.5 Å²	32.5	27%	0.266	18%	0.181	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-82.7	130.2	172	-175.2	174.6	-9.2	0	0	109.3	F159 D414 Q421 T423	F159-Q412 HydrophobicContact CD1-CB 4.49Å; F159-Q412 HydrophobicContact CD1-CG 4.11Å; F159-Q412 HydrophobicContact CE1-CB 4.01Å; F159-Q412 HydrophobicContact CE1-CG 3.95Å; F159-Q412 HydrophobicContact CE2-CB 4.05Å; F159-Q412 HydrophobicContact CZ-CB 3.79Å; F159-Q412 HydrophobicContact CZ-CG 4.25Å; Q412-D414 PolarHBondContact O-N 3.5Å; Q412-Q421 PolarHBondContact N-O 3.41Å; Q412-Q421 PolarHBondContact O-N 2.99Å; Q412-T423 HydrophobicContact CB-CG2 3.42Å; Q412-T423 VanDerWaalsContact CB-CG2 3.42Å; Q412-T423 HydrophobicContact CG-CG2 4.46Å
413	P	76.4	Confident	78.4	Confident	14 Å²	14	32.8 Å²	32.8	9%	0.091	18%	0.183	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-73.8	120.6	172.1	28	-31.6	0	0	0	110.2	N155 M420	N155-P413 HydrophobicContact CB-CB 4.24Å; N155-P413 HydrophobicContact CB-CG 3.91Å; P413-M420 HydrophobicContact CB-CE 4.13Å; P413-M420 HydrophobicContact CB-SD 4.18Å
414	D	68.2	Low	78.2	Confident	41 Å²	41	35.1 Å²	35.1	22%	0.219	20%	0.195	C	C	.	.	P	Polyproline II helix	trans	-85.8	121.9	170.7	-177.6	0.5	0	0	0	110.4	Q412 T416 T417 Q418 A419	Q412-D414 PolarHBondContact O-N 3.5Å; D414-T416 VanDerWaalsContact C-N 3.26Å; D414-T416 PolarHBondContact O-N 3.4Å; D414-T416 PolarHBondContact OD1-N 3.31Å; D414-T416 PolarHBondContact OD1-OG1 2.99Å; D414-T416 PolarHBondContact OD2-OG1 3.34Å; D414-T417 VanDerWaalsContact CG-OG1 3.31Å; D414-T417 WeakPolarHBondContact OD2-CB 3.43Å; D414-T417 WeakPolarHBondContact OD2-CG2 3.43Å; D414-T417 PolarHBondContact OD2-OG1 3.42Å; D414-Q418 VanDerWaalsContact O-CA 3.27Å; D414-Q418 WeakPolarHBondContact O-CA 3.36Å; D414-Q418 PolarHBondContact O-N 3.46Å; D414-A419 PolarHBondContact N-O 2.9Å
415	T	62.6	Low	78	Confident	98 Å²	98	38 Å²	38	60%	0.601	21%	0.213	S	C	*	.	T	Hydrogen-bonded Turn	trans	-70.9	-19.9	179.9	51.3	0	0	0	0	113.3	S156	S156-T415 WeakPolarHBondContact OG-CG2 3.3Å
416	T	58	Low	77.8	Confident	115 Å²	115	38 Å²	38	71%	0.706	21%	0.213	S	C	*	.	T	Hydrogen-bonded Turn	trans	-96	-46.3	-173.4	61.7	0	0	0	0	113	D414	D414-T416 VanDerWaalsContact C-N 3.26Å; D414-T416 PolarHBondContact O-N 3.4Å; D414-T416 PolarHBondContact OD1-N 3.31Å; D414-T416 PolarHBondContact OD1-OG1 2.99Å; D414-T416 PolarHBondContact OD2-OG1 3.34Å
417	T	56.2	Low	77.8	Confident	67 Å²	67	37.7 Å²	37.7	41%	0.411	21%	0.211	S	C	.	.	T	Hydrogen-bonded Turn	trans	-97.7	-5.5	-178.3	64.2	0	0	0	0	113.3	D414 A419	D414-T417 VanDerWaalsContact CG-OG1 3.31Å; D414-T417 WeakPolarHBondContact OD2-CB 3.43Å; D414-T417 WeakPolarHBondContact OD2-CG2 3.43Å; D414-T417 PolarHBondContact OD2-OG1 3.42Å; T417-A419 PolarHBondContact O-N 2.84Å; T417-A419 VanDerWaalsContact O-N 3.09Å; T417-A419 WeakPolarHBondContact OG1-CB 3.42Å; T417-A419 PolarHBondContact OG1-N 3.08Å
418	Q	60.4	Low	78	Confident	56 Å²	56	42.4 Å²	42.4	26%	0.262	23%	0.228	S	C	.	.			trans	52	22.2	-167.1	-58.6	-164.5	-7.7	0	0	113	V85 I90 D414	V85-Q418 HydrophobicContact CG1-CB 4.34Å; I90-Q418 HydrophobicContact CD1-CB 4.4Å; I90-Q418 WeakPolarHBondContact CD1-O 3.09Å; I90-Q418 WeakPolarHBondContact CG1-O 3.26Å; D414-Q418 VanDerWaalsContact O-CA 3.27Å; D414-Q418 WeakPolarHBondContact O-CA 3.36Å; D414-Q418 PolarHBondContact O-N 3.46Å
419	A	61.6	Low	78.3	Confident	31 Å²	31	43.6 Å²	43.6	26%	0.256	24%	0.235	S	C	.	.			trans	-84.7	154.5	177.5	0	0	0	0	0	111.7	D414 T417 Q421	D414-A419 PolarHBondContact N-O 2.9Å; T417-A419 PolarHBondContact O-N 2.84Å; T417-A419 VanDerWaalsContact O-N 3.09Å; T417-A419 WeakPolarHBondContact OG1-CB 3.42Å; T417-A419 PolarHBondContact OG1-N 3.08Å; A419-Q421 HydrophobicContact CB-CG 4.34Å
420	M	67.9	Low	78.7	Confident	36 Å²	36	43.5 Å²	43.5	18%	0.177	24%	0.235	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-104.8	120.9	170.3	-67.8	-69.9	176.1	0	0	108.1	I90 Y93 Y411 P413	I90-M420 HydrophobicContact CG1-CG 4.42Å; I90-M420 HydrophobicContact CG2-CE 4.23Å; Y93-M420 HydrophobicContact CD2-CE 4.08Å; Y93-M420 HydrophobicContact CD2-CG 3.86Å; Y93-M420 HydrophobicContact CD2-SD 4Å; Y93-M420 HydrophobicContact CE2-CG 4.25Å; Y411-M420 HydrophobicContact CD2-CB 3.88Å; Y411-M420 HydrophobicContact CG-CB 4.12Å; P413-M420 HydrophobicContact CB-CE 4.13Å; P413-M420 HydrophobicContact CB-SD 4.18Å
421	Q	71.6	Confident	79	Confident	98 Å²	98	43.3 Å²	43.3	46%	0.458	23%	0.234	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-123.7	142.4	-172	-60.3	-174.8	5.6	0	0	112	Y411 Q412 A419 T423	Y411-Q421 VanDerWaalsContact CA-O 3.29Å; Y411-Q421 WeakPolarHBondContact CA-O 3.42Å; Q412-Q421 PolarHBondContact N-O 3.41Å; Q412-Q421 PolarHBondContact O-N 2.99Å; A419-Q421 HydrophobicContact CB-CG 4.34Å; Q421-T423 WeakPolarHBondContact O-CG2 3.45Å
422	S	80.6	Confident	79.5	Confident	9 Å²	9	44.5 Å²	44.5	6%	0.063	24%	0.244	C	C	.	.			trans	-64.7	142.1	166	-65.1	0	0	0	0	110	N287 Y411	N287-S422 WeakPolarHBondContact O-CB 3.48Å; Y411-S422 WeakPolarHBondContact CE1-OG 3.35Å
423	T	85.1	Confident	80	Confident	13 Å²	13	41.8 Å²	41.8	8%	0.08	23%	0.232	C	C	.	.			trans	-139.7	145.1	-174.5	68.7	0	0	0	0	112.5	N287 Q412 Q421 P425 A426	N287-T423 PolarHBondContact O-N 3.48Å; Q412-T423 HydrophobicContact CB-CG2 3.42Å; Q412-T423 VanDerWaalsContact CB-CG2 3.42Å; Q412-T423 HydrophobicContact CG-CG2 4.46Å; Q421-T423 WeakPolarHBondContact O-CG2 3.45Å; T423-P425 VanDerWaalsContact C-CD 3.5Å; T423-A426 PolarHBondContact O-N 3.5Å
424	M	90.1	Very high	80.8	Confident	49 Å²	49	41.3 Å²	41.3	24%	0.241	23%	0.229	C	C	.	.	H	α-helix	trans	-60.9	-36.9	176.7	-74.8	-54.4	-171.2	0	0	114.9	E234 P289 A426 V427 W428	E234-M424 WeakPolarHBondContact OE1-CE 3.48Å; E234-M424 WeakPolarHBondContact OE2-CE 3.43Å; P289-M424 VanDerWaalsContact CD-SD 3.54Å; P289-M424 HydrophobicContact CG-CE 3.73Å; P289-M424 HydrophobicContact CG-CG 3.9Å; P289-M424 HydrophobicContact CG-SD 4.03Å; M424-A426 PolarHBondContact O-N 2.85Å; M424-V427 WeakPolarHBondContact O-CB 3.18Å; M424-V427 PolarHBondContact O-N 3.2Å; M424-V427 HydrophobicContact SD-CB 4.49Å; M424-V427 HydrophobicContact SD-CG2 4.16Å; M424-W428 PolarHBondContact O-N 2.87Å
425	P	90.6	Very high	82.1	Confident	60 Å²	60	42.6 Å²	42.6	39%	0.39	23%	0.231	S	C	.	.	H	α-helix	trans	-54.3	-38.9	175	-30	37.7	0	0	0	113.6	L163 T423 W428 V429	L163-P425 HydrophobicContact CD1-CB 4.07Å; T423-P425 VanDerWaalsContact C-CD 3.5Å; P425-W428 PolarHBondContact O-N 3.29Å; P425-V429 WeakPolarHBondContact O-CB 2.9Å; P425-V429 VanDerWaalsContact O-CG2 3.3Å; P425-V429 WeakPolarHBondContact O-CG2 3.5Å; P425-V429 PolarHBondContact O-N 3.24Å
426	A	89.8	Confident	83.7	Confident	0 Å²	0	42.1 Å²	42.1	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-64.1	-40.5	175.9	0	0	0	0	0	112.3	L163 N287 W410 T423 M424 K430	L163-A426 HydrophobicContact CD2-CB 4.37Å; N287-A426 HydrophobicContact CB-CB 4.15Å; W410-A426 HydrophobicContact CB-CB 3.92Å; W410-A426 HydrophobicContact CD2-CB 4.48Å; W410-A426 HydrophobicContact CE3-CB 3.82Å; T423-A426 PolarHBondContact O-N 3.5Å; M424-A426 PolarHBondContact O-N 2.85Å; A426-K430 WeakPolarHBondContact O-CG 3.38Å; A426-K430 PolarHBondContact O-N 2.93Å
427	V	92.8	Very high	85.2	Confident	0 Å²	0	36.7 Å²	36.7	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-61.3	-52.4	175.7	-173.9	0	0	0	0	110.2	F238 A284 N287 M424 V429 K430 M431	F238-V427 HydrophobicContact CD2-CG1 4.41Å; F238-V427 HydrophobicContact CE2-CG1 3.7Å; F238-V427 HydrophobicContact CZ-CG1 4.29Å; A284-V427 HydrophobicContact CB-CG1 4.09Å; A284-V427 WeakPolarHBondContact O-CG2 3.3Å; N287-V427 VanDerWaalsContact C-CG2 3.46Å; N287-V427 HydrophobicContact CB-CG2 4Å; N287-V427 WeakPolarHBondContact O-CG2 3.49Å; M424-V427 WeakPolarHBondContact O-CB 3.18Å; M424-V427 PolarHBondContact O-N 3.2Å; M424-V427 HydrophobicContact SD-CB 4.49Å; M424-V427 HydrophobicContact SD-CG2 4.16Å; V427-V429 PolarHBondContact O-N 2.79Å; V427-K430 PolarHBondContact O-N 2.74Å; V427-M431 HydrophobicContact CG1-CG 4.37Å; V427-M431 WeakPolarHBondContact O-CG 3.22Å; V427-M431 PolarHBondContact O-N 3.48Å
428	W	94.8	Very high	87	Confident	116 Å²	116	33.8 Å²	33.8	44%	0.439	17%	0.173	S	C	.	.	H	α-helix	trans	-64.9	-39.7	-177.3	-81.2	108.1	0	0	0	112.9	F238 M424 P425 K430 M431 C432 W435	F238-W428 HydrophobicContact CE1-CH2 4.04Å; F238-W428 HydrophobicContact CE1-CZ2 4.35Å; F238-W428 HydrophobicContact CE1-CZ3 4.27Å; F238-W428 HydrophobicContact CZ-CH2 4.33Å; F238-W428 HydrophobicContact CZ-CZ2 4.19Å; M424-W428 PolarHBondContact O-N 2.87Å; P425-W428 PolarHBondContact O-N 3.29Å; W428-K430 VanDerWaalsContact C-N 3.33Å; W428-K430 PolarHBondContact O-N 3Å; W428-M431 PolarHBondContact O-N 3.47Å; W428-C432 WeakPolarHBondContact O-CB 3.31Å; W428-C432 PolarHBondContact O-N 3.26Å; W428-C432 PolarHBondContact O-SG 2.94Å; W428-W435 AromaticContact CZ3-CH2 3.83Å; W428-W435 HydrophobicContact CZ3-CH2 3.83Å; W428-W435 AromaticContact CZ3-CZ3 3.91Å; W428-W435 HydrophobicContact CZ3-CZ3 3.91Å
429	V	94.1	Very high	88.6	Confident	26 Å²	26	33 Å²	33	16%	0.158	18%	0.179	C	C	.	.	H	α-helix	trans	-56.1	-49.5	174.5	160.5	0	0	0	0	110.6	L163 F167 W410 P425 V427 S433	L163-V429 HydrophobicContact CD2-CG2 4.42Å; F167-V429 HydrophobicContact CB-CG1 3.77Å; F167-V429 HydrophobicContact CD2-CG1 4.19Å; F167-V429 HydrophobicContact CG-CG1 4.48Å; W410-V429 HydrophobicContact CH2-CG1 4.02Å; W410-V429 HydrophobicContact CZ3-CB 4.37Å; W410-V429 HydrophobicContact CZ3-CG1 3.8Å; P425-V429 WeakPolarHBondContact O-CB 2.9Å; P425-V429 VanDerWaalsContact O-CG2 3.3Å; P425-V429 WeakPolarHBondContact O-CG2 3.5Å; P425-V429 PolarHBondContact O-N 3.24Å; V427-V429 PolarHBondContact O-N 2.79Å; V429-S433 WeakPolarHBondContact O-CB 3.49Å; V429-S433 PolarHBondContact O-N 3.21Å; V429-S433 PolarHBondContact O-OG 3.36Å
430	K	94.5	Very high	89.9	Confident	4 Å²	4	34.2 Å²	34.2	2%	0.017	18%	0.181	C	C	.	.	H	α-helix	trans	-64.8	-44.5	179.7	-69.6	174.6	179.8	-176.1	0	112.2	I170 V280 S283 A284 N287 W410 A426 V427 W428 S433 S434	I170-K430 HydrophobicContact CD1-CG 4.46Å; V280-K430 HydrophobicContact CG1-CB 4.1Å; V280-K430 VanDerWaalsContact CG1-O 3.3Å; V280-K430 WeakPolarHBondContact CG1-O 3.49Å; S283-K430 PolarHBondContact O-NZ 3.34Å; S283-K430 PolarHBondContact OG-NZ 3.25Å; A284-K430 HydrophobicContact CB-CB 3.79Å; A284-K430 HydrophobicContact CB-CD 4.25Å; N287-K430 PolarHBondContact OD1-NZ 3.08Å; W410-K430 HydrophobicContact CH2-CG 4.35Å; A426-K430 WeakPolarHBondContact O-CG 3.38Å; A426-K430 PolarHBondContact O-N 2.93Å; V427-K430 PolarHBondContact O-N 2.74Å; W428-K430 VanDerWaalsContact C-N 3.33Å; W428-K430 PolarHBondContact O-N 3Å; K430-S433 PolarHBondContact O-N 3.44Å; K430-S434 PolarHBondContact O-N 2.83Å
431	M	95.4	Very high	91	Very high	0 Å²	0	32.5 Å²	32.5	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-65.6	-46	179.5	-69.6	-57.3	-60.6	0	0	112.3	F238 N242 A284 V427 W428 S433 S434 W435	F238-M431 HydrophobicContact CB-CE 3.57Å; F238-M431 HydrophobicContact CB-SD 4.18Å; F238-M431 HydrophobicContact CD1-CE 3.68Å; F238-M431 HydrophobicContact CD1-CG 4.25Å; F238-M431 HydrophobicContact CD1-SD 4.48Å; F238-M431 HydrophobicContact CD2-CG 4.39Å; F238-M431 HydrophobicContact CE1-CG 4.34Å; F238-M431 HydrophobicContact CE2-CG 4.49Å; F238-M431 HydrophobicContact CG-CE 3.71Å; F238-M431 HydrophobicContact CG-CG 4.28Å; F238-M431 HydrophobicContact CG-SD 4.17Å; F238-M431 HydrophobicContact CZ-CG 4.46Å; N242-M431 VanDerWaalsContact ND2-CE 3.26Å; N242-M431 WeakPolarHBondContact ND2-CE 3.47Å; A284-M431 HydrophobicContact CB-CG 3.84Å; A284-M431 HydrophobicContact CB-SD 3.78Å; V427-M431 HydrophobicContact CG1-CG 4.37Å; V427-M431 WeakPolarHBondContact O-CG 3.22Å; V427-M431 PolarHBondContact O-N 3.48Å; W428-M431 PolarHBondContact O-N 3.47Å; M431-S433 PolarHBondContact O-N 3.05Å; M431-S434 WeakPolarHBondContact O-CB 3.36Å; M431-S434 PolarHBondContact O-N 2.05Å; M431-S434 VanDerWaalsContact O-N 3.14Å; M431-W435 HydrophobicContact CB-CZ2 4.5Å; M431-W435 HydrophobicContact CE-CZ2 3.8Å; M431-W435 PolarHBondContact O-N 2.83Å
432	C	95.4	Very high	91.9	Very high	44 Å²	44	30.2 Å²	30.2	30%	0.297	16%	0.163	S	C	.	.	H	α-helix	trans	-62.5	-42.3	176.2	-70.1	0	0	0	0	111.6	F167 W428 S434 W435 L436	F167-C432 HydrophobicContact CE2-CB 4.18Å; W428-C432 WeakPolarHBondContact O-CB 3.31Å; W428-C432 PolarHBondContact O-N 3.26Å; W428-C432 PolarHBondContact O-SG 2.94Å; C432-S434 VanDerWaalsContact C-N 3.28Å; C432-S434 PolarHBondContact O-N 2.69Å; C432-W435 PolarHBondContact O-N 3.34Å; C432-L436 WeakPolarHBondContact O-CB 3.3Å; C432-L436 WeakPolarHBondContact O-CG 2.91Å; C432-L436 PolarHBondContact O-N 3.36Å
433	S	93.6	Very high	92.3	Very high	1 Å²	1	35.5 Å²	35.5	1%	0.007	18%	0.182	C	C	.	.	H	α-helix	trans	-59.1	-40.8	173.1	-67.9	0	0	0	0	111.7	F167 V429 K430 M431 G437	F167-S433 WeakPolarHBondContact CD2-OG 3.48Å; F167-S433 WeakPolarHBondContact CE2-OG 3.39Å; F167-S433 PolarHBondContact O-OG 3.44Å; V429-S433 WeakPolarHBondContact O-CB 3.49Å; V429-S433 PolarHBondContact O-N 3.21Å; V429-S433 PolarHBondContact O-OG 3.36Å; K430-S433 PolarHBondContact O-N 3.44Å; M431-S433 PolarHBondContact O-N 3.05Å; S433-G437 WeakPolarHBondContact O-CA 3.41Å; S433-G437 PolarHBondContact O-N 3.48Å
434	S	94	Very high	92.2	Very high	3 Å²	3	35.9 Å²	35.9	2%	0.021	18%	0.184	C	C	.	.	H	α-helix	trans	-62.4	-46.7	176.6	-170.3	0	0	0	0	112.1	K430 M431 C432 G437 L438	K430-S434 PolarHBondContact O-N 2.83Å; M431-S434 WeakPolarHBondContact O-CB 3.36Å; M431-S434 PolarHBondContact O-N 2.05Å; M431-S434 VanDerWaalsContact O-N 3.14Å; C432-S434 VanDerWaalsContact C-N 3.28Å; C432-S434 PolarHBondContact O-N 2.69Å; S434-G437 PolarHBondContact O-N 3.03Å; S434-L438 WeakPolarHBondContact O-CG 3.47Å; S434-L438 PolarHBondContact O-N 2.94Å
435	W	95.7	Very high	92	Very high	68 Å²	68	33.6 Å²	33.6	26%	0.258	17%	0.173	S	C	.	.	H	α-helix	trans	-69.2	-45.5	-178	-62.3	-21.3	0	0	0	112.9	F238 L241 N242 F245 W428 M431 C432 G437 L438 G439	F238-W435 HydrophobicContact CD1-CZ2 4.28Å; F238-W435 HydrophobicContact CE1-CH2 4.5Å; L241-W435 HydrophobicContact CD1-CZ2 4.13Å; N242-W435 PolarHBondContact OD1-NE1 3.43Å; F245-W435 AromaticContact CD2-CD1 3.79Å; F245-W435 AromaticContact CE2-CD1 3.53Å; F245-W435 HydrophobicContact CE2-CD2 4.49Å; F245-W435 HydrophobicContact CE2-CG 4.04Å; F245-W435 AromaticContact CE2-NE1 3.69Å; W428-W435 AromaticContact CZ3-CH2 3.83Å; W428-W435 HydrophobicContact CZ3-CH2 3.83Å; W428-W435 AromaticContact CZ3-CZ3 3.91Å; W428-W435 HydrophobicContact CZ3-CZ3 3.91Å; M431-W435 HydrophobicContact CB-CZ2 4.5Å; M431-W435 HydrophobicContact CE-CZ2 3.8Å; M431-W435 PolarHBondContact O-N 2.83Å; C432-W435 PolarHBondContact O-N 3.34Å; W435-G437 PolarHBondContact O-N 2.73Å; W435-L438 PolarHBondContact O-N 3.24Å; W435-G439 PolarHBondContact O-N 3.18Å
436	L	94.8	Very high	91.9	Very high	89 Å²	89	33.1 Å²	33.1	47%	0.466	17%	0.167	S	C	.	.	H	α-helix	trans	-59.1	-39.8	173.1	-73.8	173.3	0	0	0	110.7	F167 L171 C432 G439 L440	F167-L436 HydrophobicContact CE2-CD1 4.04Å; F167-L436 HydrophobicContact CZ-CD1 3.51Å; L171-L436 HydrophobicContact CD1-CD1 4.5Å; L171-L436 HydrophobicContact CD2-CB 3.85Å; L171-L436 HydrophobicContact CD2-CD1 4.49Å; C432-L436 WeakPolarHBondContact O-CB 3.3Å; C432-L436 WeakPolarHBondContact O-CG 2.91Å; C432-L436 PolarHBondContact O-N 3.36Å; L436-G439 CarbonylContact O-C 3.58Å; L436-G439 WeakPolarHBondContact O-CA 3.45Å; L436-G439 PolarHBondContact O-N 3.47Å; L436-L440 WeakPolarHBondContact O-CG 3.44Å; L436-L440 PolarHBondContact O-N 3.2Å
437	G	90.9	Very high	91.7	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-61.4	-48.1	176.7	0	0	0	0	0	115.3	S433 S434 W435 G439 L440 Y441	S433-G437 WeakPolarHBondContact O-CA 3.41Å; S433-G437 PolarHBondContact O-N 3.48Å; S434-G437 PolarHBondContact O-N 3.03Å; W435-G437 PolarHBondContact O-N 2.73Å; G437-G439 VanDerWaalsContact C-N 3.26Å; G437-G439 PolarHBondContact O-N 2.84Å; G437-L440 PolarHBondContact O-N 3.42Å; G437-Y441 PolarHBondContact O-N 3.48Å
438	L	93.3	Very high	91.1	Very high	7 Å²	7	34.1 Å²	34.1	4%	0.037	17%	0.173	C	C	.	.	H	α-helix	trans	-61.1	-38.7	172.1	-74.3	163.4	0	0	0	111.3	F245 I249 I273 T277 S434 W435 Y441 L442	F245-L438 HydrophobicContact CB-CD1 3.8Å; F245-L438 HydrophobicContact CD2-CD1 4.09Å; F245-L438 HydrophobicContact CG-CD1 4.4Å; I249-L438 HydrophobicContact CD1-CD2 3.7Å; I249-L438 HydrophobicContact CG2-CD2 4.4Å; I273-L438 HydrophobicContact CG2-CD2 4Å; T277-L438 HydrophobicContact CG2-CD1 3.84Å; S434-L438 WeakPolarHBondContact O-CG 3.47Å; S434-L438 PolarHBondContact O-N 2.94Å; W435-L438 PolarHBondContact O-N 3.24Å; L438-Y441 PolarHBondContact O-N 3.19Å; L438-L442 VanDerWaalsContact O-CB 3.31Å; L438-L442 WeakPolarHBondContact O-CB 3.46Å; L438-L442 PolarHBondContact O-N 3.35Å
439	G	93.5	Very high	90.5	Very high	38 Å²	38	32 Å²	32	39%	0.392	17%	0.17	S	C	.	.	H	α-helix	trans	-61.1	-42.3	173.1	0	0	0	0	0	112.8	W435 L436 G437 L442 W443	W435-G439 PolarHBondContact O-N 3.18Å; L436-G439 CarbonylContact O-C 3.58Å; L436-G439 WeakPolarHBondContact O-CA 3.45Å; L436-G439 PolarHBondContact O-N 3.47Å; G437-G439 VanDerWaalsContact C-N 3.26Å; G437-G439 PolarHBondContact O-N 2.84Å; G439-L442 PolarHBondContact O-N 2.57Å; G439-W443 VanDerWaalsContact O-CB 3.29Å; G439-W443 WeakPolarHBondContact O-CB 3.13Å; G439-W443 PolarHBondContact O-N 2.84Å
440	L	89.9	Confident	90.1	Very high	58 Å²	58	35.1 Å²	35.1	30%	0.304	19%	0.185	S	C	.	.	H	α-helix	trans	-64.6	-43.2	174.9	-72.8	173.2	0	0	0	111.6	I175 L436 G437 W443 T444	I175-L440 HydrophobicContact CD1-CD1 4.26Å; I175-L440 HydrophobicContact CG1-CD1 4.25Å; L436-L440 WeakPolarHBondContact O-CG 3.44Å; L436-L440 PolarHBondContact O-N 3.2Å; G437-L440 PolarHBondContact O-N 3.42Å; L440-W443 WeakPolarHBondContact O-CB 3.21Å; L440-W443 PolarHBondContact O-N 3.09Å; L440-T444 VanDerWaalsContact O-CG2 3.28Å; L440-T444 WeakPolarHBondContact O-CG2 3.37Å; L440-T444 PolarHBondContact O-N 3.4Å
441	Y	89.8	Confident	89.6	Confident	0 Å²	0	39.5 Å²	39.5	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-61.9	-47.7	174.6	179.8	-116.9	0	0	0	111.5	I178 H182 I249 S253 Q269 A270 I273 G437 L438 W443 T444 L445	I178-Y441 HydrophobicContact CD1-CD2 4.25Å; I178-Y441 HydrophobicContact CD1-CG 4.45Å; I178-Y441 HydrophobicContact CG1-CD2 3.97Å; I178-Y441 HydrophobicContact CG1-CG 4.47Å; I178-Y441 HydrophobicContact CG2-CD2 3.91Å; I178-Y441 HydrophobicContact CG2-CE2 4.46Å; H182-Y441 AromaticContact NE2-CE2 3.8Å; I249-Y441 HydrophobicContact CB-CD1 4.1Å; I249-Y441 HydrophobicContact CB-CE1 4.11Å; I249-Y441 HydrophobicContact CD1-CD1 3.98Å; I249-Y441 HydrophobicContact CD1-CE1 4.07Å; I249-Y441 HydrophobicContact CG2-CD1 4.19Å; S253-Y441 PolarHBondContact OG-OH 2.86Å; Q269-Y441 HydrophobicContact CB-CE2 4.35Å; Q269-Y441 WeakPolarHBondContact CB-OH 3.44Å; A270-Y441 HydrophobicContact CB-CE1 4.36Å; A270-Y441 PolarHBondContact N-OH 3.39Å; I273-Y441 HydrophobicContact CG1-CD2 4.25Å; I273-Y441 HydrophobicContact CG1-CE2 4.36Å; I273-Y441 HydrophobicContact CG1-CG 4.35Å; I273-Y441 HydrophobicContact CG2-CD1 4.3Å; I273-Y441 HydrophobicContact CG2-CG 4.41Å; G437-Y441 PolarHBondContact O-N 3.48Å; L438-Y441 PolarHBondContact O-N 3.19Å; Y441-W443 PolarHBondContact O-N 3.18Å; Y441-T444 PolarHBondContact O-N 3.13Å; Y441-T444 PolarHBondContact O-OG1 3.4Å; Y441-L445 HydrophobicContact CD1-CD1 4.36Å; Y441-L445 HydrophobicContact CE1-CD1 3.8Å; Y441-L445 HydrophobicContact CE2-CG 4.49Å; Y441-L445 PolarHBondContact O-N 3.1Å
442	L	91.2	Very high	88.3	Confident	49 Å²	49	44 Å²	44	26%	0.257	23%	0.234	S	C	.	.	H	α-helix	trans	-57.7	-41.6	175.9	-176.1	63.7	0	0	0	111.3	V252 L438 G439 T444 L445 I446	V252-L442 HydrophobicContact CB-CD1 4.14Å; V252-L442 HydrophobicContact CG1-CD1 3.72Å; V252-L442 HydrophobicContact CG2-CD1 4.08Å; L438-L442 VanDerWaalsContact O-CB 3.31Å; L438-L442 WeakPolarHBondContact O-CB 3.46Å; L438-L442 PolarHBondContact O-N 3.35Å; G439-L442 PolarHBondContact O-N 2.57Å; L442-T444 VanDerWaalsContact C-N 3.34Å; L442-T444 PolarHBondContact O-N 3.29Å; L442-L445 PolarHBondContact O-N 3.17Å; L442-I446 HydrophobicContact CD1-CD1 3.69Å; L442-I446 HydrophobicContact CD1-CG1 4.32Å; L442-I446 HydrophobicContact CD2-CD1 4.38Å; L442-I446 HydrophobicContact CG-CD1 3.74Å; L442-I446 WeakPolarHBondContact O-CG1 3.48Å; L442-I446 PolarHBondContact O-N 3.4Å
443	W	88.4	Confident	86.9	Confident	120 Å²	120	49.7 Å²	49.7	46%	0.455	26%	0.261	S	S	.	.	H	α-helix	trans	-62.8	-38.5	175.4	-173.8	-102.7	0	0	0	112.4	G439 L440 Y441 L445 I446 A447 F451	G439-W443 VanDerWaalsContact O-CB 3.29Å; G439-W443 WeakPolarHBondContact O-CB 3.13Å; G439-W443 PolarHBondContact O-N 2.84Å; L440-W443 WeakPolarHBondContact O-CB 3.21Å; L440-W443 PolarHBondContact O-N 3.09Å; Y441-W443 PolarHBondContact O-N 3.18Å; W443-L445 PolarHBondContact O-N 3.35Å; W443-I446 PolarHBondContact O-N 3.4Å; W443-A447 HydrophobicContact CD2-CB 4.33Å; W443-A447 HydrophobicContact CG-CB 4.48Å; W443-A447 HydrophobicContact CZ2-CB 4.33Å; W443-A447 WeakPolarHBondContact O-CB 3.4Å; W443-A447 PolarHBondContact O-N 2.82Å; W443-F451 AromaticContact CH2-CE2 3.82Å; W443-F451 HydrophobicContact CH2-CE2 3.82Å; W443-F451 AromaticContact CZ2-CE2 3.9Å; W443-F451 HydrophobicContact CZ2-CE2 3.9Å
444	T	84.3	Confident	85.5	Confident	21 Å²	21	55.1 Å²	55.1	13%	0.129	28%	0.281	C	S	.	.	H	α-helix	trans	-61.8	-31.8	176.9	60.7	0	0	0	0	112.7	L440 Y441 L442 P448	L440-T444 VanDerWaalsContact O-CG2 3.28Å; L440-T444 WeakPolarHBondContact O-CG2 3.37Å; L440-T444 PolarHBondContact O-N 3.4Å; Y441-T444 PolarHBondContact O-N 3.13Å; Y441-T444 PolarHBondContact O-OG1 3.4Å; L442-T444 VanDerWaalsContact C-N 3.34Å; L442-T444 PolarHBondContact O-N 3.29Å; T444-P448 WeakPolarHBondContact O-CD 3.15Å
445	L	85.1	Confident	83.6	Confident	1 Å²	1	62.3 Å²	62.3	1%	0.005	32%	0.319	C	S	.	.	H	α-helix	trans	-80.3	-35.9	177.1	-60.5	173.3	0	0	0	113.1	V252 S253 I258 S265 Y441 L442 W443	V252-L445 HydrophobicContact CG1-CD1 4.25Å; S253-L445 VanDerWaalsContact OG-CD1 3.3Å; S253-L445 WeakPolarHBondContact OG-CD1 3.36Å; I258-L445 HydrophobicContact CG2-CB 4.22Å; I258-L445 HydrophobicContact CG2-CD2 4.44Å; S265-L445 WeakPolarHBondContact OG-CD2 3.28Å; Y441-L445 HydrophobicContact CD1-CD1 4.36Å; Y441-L445 HydrophobicContact CE1-CD1 3.8Å; Y441-L445 HydrophobicContact CE2-CG 4.49Å; Y441-L445 PolarHBondContact O-N 3.1Å; L442-L445 PolarHBondContact O-N 3.17Å; W443-L445 PolarHBondContact O-N 3.35Å
446	I	87.6	Confident	81.5	Confident	51 Å²	51	60.9 Å²	60.9	26%	0.262	32%	0.315	S	S	.	.	H	α-helix	trans	-91.1	-31.3	-172.5	-64.6	178.1	0	0	0	112.5	V252 I258 L442 W443 P448 L449 I450	V252-I446 HydrophobicContact CG1-CG1 4.38Å; I258-I446 HydrophobicContact CD1-CG1 4.46Å; L442-I446 HydrophobicContact CD1-CD1 3.69Å; L442-I446 HydrophobicContact CD1-CG1 4.32Å; L442-I446 HydrophobicContact CD2-CD1 4.38Å; L442-I446 HydrophobicContact CG-CD1 3.74Å; L442-I446 WeakPolarHBondContact O-CG1 3.48Å; L442-I446 PolarHBondContact O-N 3.4Å; W443-I446 PolarHBondContact O-N 3.4Å; I446-P448 VanDerWaalsContact C-CD 3.48Å; I446-L449 WeakPolarHBondContact O-CB 3.46Å; I446-L449 PolarHBondContact O-N 2.93Å; I446-I450 HydrophobicContact CG2-CD1 3.43Å; I446-I450 VanDerWaalsContact CG2-CD1 3.43Å; I446-I450 HydrophobicContact CG2-CG1 3.77Å; I446-I450 PolarHBondContact O-N 3.12Å
447	A	86.1	Confident	78.8	Confident	1 Å²	1	65.3 Å²	65.3	1%	0.008	34%	0.339	C	S	.	.	H	α-helix	trans	-56.1	-40.3	-175.3	0	0	0	0	0	114.2	W443 L449 I450 F451 F456	W443-A447 HydrophobicContact CD2-CB 4.33Å; W443-A447 HydrophobicContact CG-CB 4.48Å; W443-A447 HydrophobicContact CZ2-CB 4.33Å; W443-A447 WeakPolarHBondContact O-CB 3.4Å; W443-A447 PolarHBondContact O-N 2.82Å; A447-L449 PolarHBondContact O-N 3.18Å; A447-I450 PolarHBondContact O-N 2.88Å; A447-F451 PolarHBondContact O-N 3.37Å; A447-F456 HydrophobicContact CB-CE1 4.02Å; A447-F456 HydrophobicContact CB-CZ 3.94Å; A447-F456 WeakPolarHBondContact O-CZ 3.47Å
448	P	81.8	Confident	78.2	Confident	19 Å²	19	68.6 Å²	68.6	12%	0.123	36%	0.356	C	S	.	.	H	α-helix	trans	-59.7	-29	174.7	-25.9	36.9	0	0	0	114.2	A261 T444 I446 F456	A261-P448 HydrophobicContact CB-CB 4.2Å; T444-P448 WeakPolarHBondContact O-CD 3.15Å; I446-P448 VanDerWaalsContact C-CD 3.48Å; P448-F456 HydrophobicContact CB-CD2 4.21Å; P448-F456 HydrophobicContact CB-CE2 4.42Å; P448-F456 HydrophobicContact CG-CD2 4.33Å; P448-F456 HydrophobicContact CG-CG 4.48Å
449	L	82.1	Confident	77.4	Confident	72 Å²	72	71.8 Å²	71.8	38%	0.377	37%	0.373	S	S	.	.	H	α-helix	trans	-79.9	-37.4	177.9	-74.1	174.3	0	0	0	113.4	K257 I258 A261 I446 A447	K257-L449 HydrophobicContact CB-CD1 4.39Å; K257-L449 WeakPolarHBondContact O-CD2 3.46Å; I258-L449 HydrophobicContact CB-CD1 4.42Å; I258-L449 HydrophobicContact CD1-CD1 4.41Å; I258-L449 HydrophobicContact CG1-CD1 3.41Å; I258-L449 VanDerWaalsContact CG1-CD1 3.41Å; A261-L449 HydrophobicContact CB-CD2 3.55Å; A261-L449 HydrophobicContact CB-CG 3.86Å; I446-L449 WeakPolarHBondContact O-CB 3.46Å; I446-L449 PolarHBondContact O-N 2.93Å; A447-L449 PolarHBondContact O-N 3.18Å
450	I	84.8	Confident	76.5	Confident	92 Å²	92	73.7 Å²	73.7	47%	0.472	37%	0.372	S	S	.	.	H	α-helix	trans	-78	-33.7	-177.8	-62.2	-179.5	0	0	0	111	I446 A447 P452	I446-I450 HydrophobicContact CG2-CD1 3.43Å; I446-I450 VanDerWaalsContact CG2-CD1 3.43Å; I446-I450 HydrophobicContact CG2-CG1 3.77Å; I446-I450 PolarHBondContact O-N 3.12Å; A447-I450 PolarHBondContact O-N 2.88Å; I450-P452 VanDerWaalsContact C-CD 3.4Å; I450-P452 WeakPolarHBondContact O-CD 3.46Å
451	F	82.9	Confident	75.8	Confident	95 Å²	95	74.6 Å²	74.6	42%	0.417	38%	0.376	S	S	.	.			trans	-123.1	62.1	-175.5	-57.1	-74.6	0	0	0	112.1	W443 A447 D453 R454 F456	W443-F451 AromaticContact CH2-CE2 3.82Å; W443-F451 HydrophobicContact CH2-CE2 3.82Å; W443-F451 AromaticContact CZ2-CE2 3.9Å; W443-F451 HydrophobicContact CZ2-CE2 3.9Å; A447-F451 PolarHBondContact O-N 3.37Å; F451-D453 PolarHBondContact O-N 3.17Å; F451-D453 VanDerWaalsContact O-N 3.08Å; F451-R454 HydrophobicContact CB-CB 4.14Å; F451-R454 WeakPolarHBondContact O-CB 3.27Å; F451-R454 PolarHBondContact O-N 2.75Å; F451-F456 HydrophobicContact CB-CE2 4.11Å; F451-F456 HydrophobicContact CB-CZ 4.03Å; F451-F456 WeakPolarHBondContact O-CE2 3.11Å
452	P	68.3	Low	74.9	Confident	96 Å²	96	79.3 Å²	79.3	62%	0.623	40%	0.399	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.5	-25.6	-174.5	24.9	-34.5	0	0	0	113.8	I450 R454	I450-P452 VanDerWaalsContact C-CD 3.4Å; I450-P452 WeakPolarHBondContact O-CD 3.46Å; P452-R454 VanDerWaalsContact C-N 3.3Å; P452-R454 PolarHBondContact O-N 2.87Å
453	D	66.6	Low	73.8	Confident	162 Å²	162	81.3 Å²	81.3	87%	0.866	41%	0.409	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83	0.3	179.4	-57.2	-47.6	0	0	0	114.1	F451	F451-D453 PolarHBondContact O-N 3.17Å; F451-D453 VanDerWaalsContact O-N 3.08Å
454	R	63.8	Low	72.7	Confident	116 Å²	116	78.5 Å²	78.5	44%	0.438	41%	0.406	S	S	.	.	S	Bend	trans	-97.2	123.3	177.7	-165.2	175.7	106.7	164.4	6.3	109.1	F451 P452 F456	F451-R454 HydrophobicContact CB-CB 4.14Å; F451-R454 WeakPolarHBondContact O-CB 3.27Å; F451-R454 PolarHBondContact O-N 2.75Å; P452-R454 VanDerWaalsContact C-N 3.3Å; P452-R454 PolarHBondContact O-N 2.87Å; R454-F456 HydrophobicContact CB-CD2 4.42Å; R454-F456 HydrophobicContact CB-CE2 3.9Å; R454-F456 HydrophobicContact CB-CZ 4.07Å; R454-F456 HydrophobicContact CG-CZ 4.43Å; R454-F456 VanDerWaalsContact NE-CE1 3.27Å; R454-F456 WeakPolarHBondContact O-CD2 3.29Å; R454-F456 WeakPolarHBondContact O-CE2 3.45Å; R454-F456 PolarHBondContact O-N 3.14Å
455	D	55.3	Low	71.9	Confident	153 Å²	153	82.9 Å²	82.9	82%	0.818	43%	0.427	S	S	*	.			trans	-60.2	112.7	173.4	-69.5	-38	0	0	0	109.9
456	F	51.9	Low	70.8	Confident	39 Å²	39	89.8 Å²	89.8	17%	0.171	46%	0.462	C	S	.	.			trans	-106	0.9	174.2	-68	-73.6	0	0	0	112.7	Q350 A447 P448 F451 R454	Q350-F456 HydrophobicContact CG-CD1 4.44Å; A447-F456 HydrophobicContact CB-CE1 4.02Å; A447-F456 HydrophobicContact CB-CZ 3.94Å; A447-F456 WeakPolarHBondContact O-CZ 3.47Å; P448-F456 HydrophobicContact CB-CD2 4.21Å; P448-F456 HydrophobicContact CB-CE2 4.42Å; P448-F456 HydrophobicContact CG-CD2 4.33Å; P448-F456 HydrophobicContact CG-CG 4.48Å; F451-F456 HydrophobicContact CB-CE2 4.11Å; F451-F456 HydrophobicContact CB-CZ 4.03Å; F451-F456 WeakPolarHBondContact O-CE2 3.11Å; R454-F456 HydrophobicContact CB-CD2 4.42Å; R454-F456 HydrophobicContact CB-CE2 3.9Å; R454-F456 HydrophobicContact CB-CZ 4.07Å; R454-F456 HydrophobicContact CG-CZ 4.43Å; R454-F456 VanDerWaalsContact NE-CE1 3.27Å; R454-F456 WeakPolarHBondContact O-CD2 3.29Å; R454-F456 WeakPolarHBondContact O-CE2 3.45Å; R454-F456 PolarHBondContact O-N 3.14Å
457	N	38.1	Very low	69.2	Low	181 Å²	181	93.3 Å²	93.3	97%	0.968	48%	0.48	S	S	*	.			trans	-73.6	0	179.3	-78.3	-20.6	0	0	0	112.6	A349	A349-N457 WeakPolarHBondContact CB-O 3.48Å; A349-N457 WeakPolarHBondContact CB-OXT 3.39Å

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