A0A087XUD0_POEFO Loading...

Carbonic anhydrase

Reversible hydration of carbon dioxide.

AlphaFold DB , UniProt , Accession A0A087XUD0, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 260 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M34Very low79.9Confident217 Ų21787.5 Ų87.5100%1.06952%0.52SS*.  0118.10-69.3-162.1-95.100106.2H3M1-H3 PolarHBondContact O-N 3.33Å
2S46Very low81.3Confident120 Ų12080.3 Ų80.384%0.83948%0.477SS*.  trans-69.5111.7173.444.60000107.3A4S2-A4 PolarHBondContact O-N 3.33Å
3H56.9Low82.5Confident95 Ų9576.4 Ų76.444%0.4446%0.455SS..  trans-71.997.9173-68.6-81.3000107.4M1 W5 S19 F20M1-H3 PolarHBondContact O-N 3.33Å; H3-W5 PolarHBondContact O-N 3.26Å; H3-S19 WeakPolarHBondContact ND1-CB 3.49Å; H3-S19 PolarHBondContact ND1-OG 3.24Å; H3-F20 HydrophobicContact CB-CE2 4.03Å; H3-F20 HydrophobicContact CB-CZ 3.74Å
4A83.6Confident83.5Confident90 Ų9078.7 Ų78.774%0.74446%0.464SS*.  trans-66.4123.8178.300000109.5S2S2-A4 PolarHBondContact O-N 3.33Å
5W94.9Very high84.4Confident49 Ų4978.9 Ų78.919%0.18646%0.457CS..  trans-129.6163.9176.667.6-88.3000109.3H3 Y7 W16 F20 H64 T199 P200H3-W5 PolarHBondContact O-N 3.26Å; W5-Y7 AromaticContact CZ3-CE2 3.87Å; W5-Y7 HydrophobicContact CZ3-CE2 3.87Å; W5-Y7 AromaticContact CZ3-CZ 3.91Å; W5-W16 AromaticContact CE3-CE2 3.77Å; W5-W16 HydrophobicContact CE3-CH2 4.27Å; W5-W16 AromaticContact CE3-CZ2 3.48Å; W5-W16 HydrophobicContact CE3-CZ2 3.48Å; W5-W16 VanDerWaalsContact CE3-CZ2 3.48Å; W5-W16 AromaticContact CE3-NE1 3.97Å; W5-W16 HydrophobicContact CZ3-CH2 4.14Å; W5-W16 AromaticContact CZ3-CZ2 3.71Å; W5-W16 HydrophobicContact CZ3-CZ2 3.71Å; W5-F20 HydrophobicContact CB-CE2 4.5Å; W5-H64 HydrophobicContact CH2-CB 3.9Å; W5-H64 AromaticContact CH2-CD2 3.99Å; W5-H64 AromaticContact CH2-CG 3.62Å; W5-H64 AromaticContact CH2-ND1 3.82Å; W5-H64 HydrophobicContact CZ2-CB 4.49Å; W5-H64 AromaticContact CZ2-CD2 3.74Å; W5-H64 AromaticContact CZ2-CG 3.86Å; W5-H64 AromaticContact CZ2-NE2 3.92Å; W5-H64 AromaticContact CZ3-ND1 3.92Å; W5-H64 PolarHBondContact O-CE1 3.27Å; W5-H64 VanDerWaalsContact O-CE1 3.29Å; W5-T199 HydrophobicContact CH2-CG2 3.66Å; W5-T199 HydrophobicContact CZ3-CG2 4.13Å; W5-P200 HydrophobicContact CB-CG 4.06Å; W5-P200 HydrophobicContact CD2-CB 4Å; W5-P200 HydrophobicContact CD2-CG 3.55Å; W5-P200 HydrophobicContact CE3-CG 3.92Å; W5-P200 HydrophobicContact CG-CB 3.9Å; W5-P200 HydrophobicContact CG-CG 3.6Å
6G95.8Very high85.2Confident7 Ų774.4 Ų74.47%0.07243%0.43CS..  trans-174-149.7176.100000110.5T11 G12 W16G6-T11 CarbonylContact C-O 3.54Å; G6-T11 PolarHBondContact N-O 3.17Å; G6-T11 CarbonylContact O-C 3.39Å; G6-G12 VanDerWaalsContact O-CA 3.31Å; G6-G12 WeakPolarHBondContact O-CA 3.32Å; G6-W16 WeakPolarHBondContact O-CZ2 3.37Å; G6-W16 PolarHBondContact O-NE1 3.23Å
7Y96.7Very high85.8Confident37 Ų3771.5 Ų71.515%0.14542%0.417CS..SBendtrans-1216-179.6-60.3-83.6000113.2W5 P13 W16 T199 F230 N243W5-Y7 AromaticContact CZ3-CE2 3.87Å; W5-Y7 HydrophobicContact CZ3-CE2 3.87Å; W5-Y7 AromaticContact CZ3-CZ 3.91Å; Y7-P13 HydrophobicContact CD1-CG 4.15Å; Y7-P13 HydrophobicContact CE1-CG 4.44Å; Y7-W16 HydrophobicContact CD1-CH2 4.48Å; Y7-W16 HydrophobicContact CD1-CZ2 4.18Å; Y7-W16 AromaticContact CE1-CH2 3.7Å; Y7-W16 HydrophobicContact CE1-CH2 3.7Å; Y7-W16 AromaticContact CE1-CZ2 3.75Å; Y7-W16 HydrophobicContact CE1-CZ2 3.75Å; Y7-T199 WeakPolarHBondContact OH-CG2 3.48Å; Y7-F230 AromaticContact CD2-CE1 3.92Å; Y7-F230 HydrophobicContact CD2-CE1 3.92Å; Y7-F230 AromaticContact CD2-CZ 3.93Å; Y7-F230 HydrophobicContact CD2-CZ 3.93Å; Y7-F230 HydrophobicContact CE2-CE1 4.47Å; Y7-N243 HydrophobicContact CD2-CB 3.89Å; Y7-N243 WeakPolarHBondContact CE1-O 3.24Å; Y7-N243 HydrophobicContact CE2-CB 3.73Å; Y7-N243 HydrophobicContact CG-CB 4.49Å; Y7-N243 VanDerWaalsContact CZ-C 3.4Å; Y7-N243 PolarHBondContact OH-O 3.45Å; Y7-N243 VanDerWaalsContact OH-O 3.08Å
8G93.5Very high86.3Confident39 Ų3974.8 Ų74.840%0.40243%0.433SS..SBendtrans-80.8169.4178.500000113.5H10 T11 G12G8-H10 PolarHBondContact O-N 3.4Å; G8-T11 PolarHBondContact O-N 3.44Å; G8-T11 VanDerWaalsContact O-N 3.1Å; G8-G12 VanDerWaalsContact O-CA 3.32Å; G8-G12 WeakPolarHBondContact O-CA 3.33Å; G8-G12 PolarHBondContact O-N 3.31Å
9A90.8Very high86.8Confident84 Ų8473.5 Ų73.569%0.69443%0.428SS*.THydrogen-bonded Turntrans-55.8-23.2-173.800000116
10H92.5Very high87.3Confident169 Ų16971.7 Ų71.778%0.78242%0.415SS*.THydrogen-bonded Turntrans-111.3-9.3-178-58.4-51.3000114G8G8-H10 PolarHBondContact O-N 3.4Å
11T94.4Very high87.7Confident56 Ų5673.1 Ų73.134%0.34443%0.427SS..THydrogen-bonded Turntrans-128.84.2-175.255.70000112.7G6 G8 W16G6-T11 CarbonylContact C-O 3.54Å; G6-T11 PolarHBondContact N-O 3.17Å; G6-T11 CarbonylContact O-C 3.39Å; G8-T11 PolarHBondContact O-N 3.44Å; G8-T11 VanDerWaalsContact O-N 3.1Å; T11-W16 VanDerWaalsContact O-CD1 3.29Å; T11-W16 PolarHBondContact O-NE1 2.96Å
12G96.7Very high90.7Very high1 Ų165.6 Ų65.61%0.0139%0.39CS..SBendtrans-72.4175.9-173.200000115.3G6 G8 D14 K15 W16G6-G12 VanDerWaalsContact O-CA 3.31Å; G6-G12 WeakPolarHBondContact O-CA 3.32Å; G8-G12 VanDerWaalsContact O-CA 3.32Å; G8-G12 WeakPolarHBondContact O-CA 3.33Å; G8-G12 PolarHBondContact O-N 3.31Å; G12-D14 PolarHBondContact O-N 2.82Å; G12-D14 VanDerWaalsContact O-N 3.08Å; G12-K15 WeakPolarHBondContact O-CA 3.29Å; G12-K15 WeakPolarHBondContact O-CB 3.46Å; G12-K15 PolarHBondContact O-N 3.1Å; G12-W16 VanDerWaalsContact C-NE1 3.32Å; G12-W16 PolarHBondContact O-N 2.81Å; G12-W16 PolarHBondContact O-NE1 2.97Å
13P97.4Very high93.2Very high29 Ų2960 Ų6019%0.18835%0.352CS..THydrogen-bonded Turntrans-51.5-32.6-177-32.237.3000116.3Y7 K15 W16 R245Y7-P13 HydrophobicContact CD1-CG 4.15Å; Y7-P13 HydrophobicContact CE1-CG 4.44Å; P13-K15 PolarHBondContact O-N 2.95Å; P13-W16 HydrophobicContact CB-CD2 4.37Å; P13-W16 HydrophobicContact CB-CE3 4.3Å; P13-W16 HydrophobicContact CB-CH2 4.48Å; P13-W16 HydrophobicContact CB-CZ2 4.49Å; P13-W16 HydrophobicContact CB-CZ3 4.36Å; P13-W16 HydrophobicContact CG-CH2 3.96Å; P13-W16 HydrophobicContact CG-CZ2 3.86Å; P13-W16 HydrophobicContact CG-CZ3 4.31Å; P13-W16 PolarHBondContact O-N 3.12Å; P13-R245 HydrophobicContact CB-CG 4.05Å; P13-R245 HydrophobicContact CG-CG 4.27Å
14D96.3Very high95Very high109 Ų10961 Ų6158%0.58336%0.36SS*.THydrogen-bonded Turntrans-71.2-14.517870-52.7000113.3G12G12-D14 PolarHBondContact O-N 2.82Å; G12-D14 VanDerWaalsContact O-N 3.08Å
15K96.7Very high95.7Very high82 Ų8257.3 Ų57.336%0.35733%0.33SS..THydrogen-bonded Turntrans-102.2-15.4177-53.1-51.7-176.9-140.20113.6G12 P13 A17 D18G12-K15 WeakPolarHBondContact O-CA 3.29Å; G12-K15 WeakPolarHBondContact O-CB 3.46Å; G12-K15 PolarHBondContact O-N 3.1Å; P13-K15 PolarHBondContact O-N 2.95Å; K15-A17 PolarHBondContact O-N 2.86Å; K15-A17 VanDerWaalsContact O-N 3.12Å; K15-D18 WeakPolarHBondContact O-CB 3.26Å; K15-D18 PolarHBondContact O-N 3.37Å
16W97.3Very high95.8Very high6 Ų658.8 Ų58.82%0.02335%0.346CS..G310 helixtrans-60.3-30.3-173-67.1-5.3000113.1W5 G6 Y7 T11 G12 P13 D18 S19 F20 A23 T198 P200 L202 R245W5-W16 AromaticContact CE3-CE2 3.77Å; W5-W16 HydrophobicContact CE3-CH2 4.27Å; W5-W16 AromaticContact CE3-CZ2 3.48Å; W5-W16 HydrophobicContact CE3-CZ2 3.48Å; W5-W16 VanDerWaalsContact CE3-CZ2 3.48Å; W5-W16 AromaticContact CE3-NE1 3.97Å; W5-W16 HydrophobicContact CZ3-CH2 4.14Å; W5-W16 AromaticContact CZ3-CZ2 3.71Å; W5-W16 HydrophobicContact CZ3-CZ2 3.71Å; G6-W16 WeakPolarHBondContact O-CZ2 3.37Å; G6-W16 PolarHBondContact O-NE1 3.23Å; Y7-W16 HydrophobicContact CD1-CH2 4.48Å; Y7-W16 HydrophobicContact CD1-CZ2 4.18Å; Y7-W16 AromaticContact CE1-CH2 3.7Å; Y7-W16 HydrophobicContact CE1-CH2 3.7Å; Y7-W16 AromaticContact CE1-CZ2 3.75Å; Y7-W16 HydrophobicContact CE1-CZ2 3.75Å; T11-W16 VanDerWaalsContact O-CD1 3.29Å; T11-W16 PolarHBondContact O-NE1 2.96Å; G12-W16 VanDerWaalsContact C-NE1 3.32Å; G12-W16 PolarHBondContact O-N 2.81Å; G12-W16 PolarHBondContact O-NE1 2.97Å; P13-W16 HydrophobicContact CB-CD2 4.37Å; P13-W16 HydrophobicContact CB-CE3 4.3Å; P13-W16 HydrophobicContact CB-CH2 4.48Å; P13-W16 HydrophobicContact CB-CZ2 4.49Å; P13-W16 HydrophobicContact CB-CZ3 4.36Å; P13-W16 HydrophobicContact CG-CH2 3.96Å; P13-W16 HydrophobicContact CG-CZ2 3.86Å; P13-W16 HydrophobicContact CG-CZ3 4.31Å; P13-W16 PolarHBondContact O-N 3.12Å; W16-D18 PolarHBondContact O-N 2.58Å; W16-D18 VanDerWaalsContact O-N 3.16Å; W16-S19 PolarHBondContact O-N 2.98Å; W16-F20 WeakPolarHBondContact O-CA 3.45Å; W16-F20 WeakPolarHBondContact O-CB 3.5Å; W16-F20 WeakPolarHBondContact O-CD2 3.31Å; W16-F20 PolarHBondContact O-N 3.11Å; W16-A23 HydrophobicContact CB-CB 4.47Å; W16-T198 WeakPolarHBondContact CZ3-O 3.42Å; W16-P200 HydrophobicContact CB-CG 4.5Å; W16-P200 HydrophobicContact CD2-CG 3.69Å; W16-P200 HydrophobicContact CE3-CG 3.96Å; W16-P200 HydrophobicContact CG-CG 3.97Å; W16-P200 HydrophobicContact CZ3-CG 4.45Å; W16-L202 HydrophobicContact CB-CD1 4.24Å; W16-L202 HydrophobicContact CE3-CD1 3.95Å; W16-L202 HydrophobicContact CE3-CD2 3.89Å; W16-L202 HydrophobicContact CE3-CG 4.4Å; W16-L202 HydrophobicContact CZ3-CD2 3.92Å; W16-R245 HydrophobicContact CH2-CB 4.38Å; W16-R245 HydrophobicContact CH2-CG 4.32Å; W16-R245 HydrophobicContact CZ3-CB 4.21Å; W16-R245 HydrophobicContact CZ3-CG 3.74Å
17A96Very high95.9Very high25 Ų2561.9 Ų61.921%0.20736%0.356CS..G310 helixtrans-59.5-24.4177.200000114.2K15 S19 F20 A23 N24K15-A17 PolarHBondContact O-N 2.86Å; K15-A17 VanDerWaalsContact O-N 3.12Å; A17-S19 VanDerWaalsContact C-N 3.31Å; A17-S19 PolarHBondContact O-N 3.28Å; A17-F20 WeakPolarHBondContact CA-O 3.42Å; A17-A23 HydrophobicContact CB-CB 3.94Å; A17-N24 WeakPolarHBondContact CB-ND2 3.5Å
18D94.8Very high96Very high132 Ų13260.3 Ų60.371%0.70635%0.35SS*.G310 helixtrans-67.2-34.4-178.9-63.2-18.9000111.8K15 W16K15-D18 WeakPolarHBondContact O-CB 3.26Å; K15-D18 PolarHBondContact O-N 3.37Å; W16-D18 PolarHBondContact O-N 2.58Å; W16-D18 VanDerWaalsContact O-N 3.16Å
19S95.3Very high96.3Very high49 Ų4958.5 Ų58.534%0.34333%0.331SS..THydrogen-bonded Turntrans-106.3-24.5178.8-66.70000113.1H3 W16 A17H3-S19 WeakPolarHBondContact ND1-CB 3.49Å; H3-S19 PolarHBondContact ND1-OG 3.24Å; W16-S19 PolarHBondContact O-N 2.98Å; A17-S19 VanDerWaalsContact C-N 3.31Å; A17-S19 PolarHBondContact O-N 3.28Å
20F96.2Very high96.7Very high37 Ų3754.5 Ų54.516%0.16230%0.297CS..  trans-127.181-178-52.9-81.8000108.8H3 W5 W16 A17 I22 A23 P200 P201 L202H3-F20 HydrophobicContact CB-CE2 4.03Å; H3-F20 HydrophobicContact CB-CZ 3.74Å; W5-F20 HydrophobicContact CB-CE2 4.5Å; W16-F20 WeakPolarHBondContact O-CA 3.45Å; W16-F20 WeakPolarHBondContact O-CB 3.5Å; W16-F20 WeakPolarHBondContact O-CD2 3.31Å; W16-F20 PolarHBondContact O-N 3.11Å; A17-F20 WeakPolarHBondContact CA-O 3.42Å; F20-I22 PolarHBondContact O-N 2.94Å; F20-A23 WeakPolarHBondContact O-CB 3.32Å; F20-A23 PolarHBondContact O-N 2.82Å; F20-P200 HydrophobicContact CD1-CB 4.28Å; F20-P200 HydrophobicContact CD2-CB 3.79Å; F20-P200 HydrophobicContact CD2-CG 4.01Å; F20-P200 HydrophobicContact CE1-CB 4.03Å; F20-P200 HydrophobicContact CE2-CB 3.53Å; F20-P200 HydrophobicContact CE2-CG 3.98Å; F20-P200 HydrophobicContact CG-CB 4.16Å; F20-P200 HydrophobicContact CZ-CB 3.65Å; F20-P201 HydrophobicContact CD1-CB 4.03Å; F20-P201 HydrophobicContact CE1-CB 4.12Å; F20-L202 HydrophobicContact CB-CD1 4.37Å
21P96.4Very high97Very high102 Ų10246.5 Ų46.566%0.66226%0.26SS*.G310 helixtrans-55.6-26.5-175.4-28.736.1000114.3A23 N24P21-A23 PolarHBondContact O-N 3.41Å; P21-A23 VanDerWaalsContact O-N 3.12Å; P21-N24 PolarHBondContact O-N 3.44Å
22I97.3Very high97.2Very high60 Ų6046.5 Ų46.531%0.30826%0.258SS..G310 helixtrans-61.6-14.3173.9-160.2169.7000113.1F20 N24 G25 Q28 P201 L202 E204F20-I22 PolarHBondContact O-N 2.94Å; I22-N24 PolarHBondContact O-N 3.36Å; I22-G25 WeakPolarHBondContact O-CA 3.37Å; I22-G25 PolarHBondContact O-N 3Å; I22-Q28 WeakPolarHBondContact O-CG 3.39Å; I22-Q28 PolarHBondContact O-NE2 3.28Å; I22-Q28 PolarHBondContact O-OE1 3.15Å; I22-P201 VanDerWaalsContact CG2-O 3.22Å; I22-P201 WeakPolarHBondContact CG2-O 3.29Å; I22-L202 HydrophobicContact CG2-CB 3.97Å; I22-E204 HydrophobicContact CD1-CG 4.07Å; I22-E204 HydrophobicContact CG1-CG 4.21Å
23A97.3Very high97.3Very high3 Ų346.4 Ų46.43%0.02526%0.258CS..G310 helixtrans-53.9-25.1170.600000113.5W16 A17 F20 P21 Q28 L202 R245W16-A23 HydrophobicContact CB-CB 4.47Å; A17-A23 HydrophobicContact CB-CB 3.94Å; F20-A23 WeakPolarHBondContact O-CB 3.32Å; F20-A23 PolarHBondContact O-N 2.82Å; P21-A23 PolarHBondContact O-N 3.41Å; P21-A23 VanDerWaalsContact O-N 3.12Å; A23-Q28 WeakPolarHBondContact O-CG 3.45Å; A23-L202 HydrophobicContact CB-CD1 3.35Å; A23-R245 PolarHBondContact O-NH2 2.83Å; A23-R245 VanDerWaalsContact O-NH2 3.07Å
24N95.8Very high97.3Very high116 Ų11647.5 Ų47.562%0.6226%0.264SS*.G310 helixtrans-100.211.4174.4-71-41.5000113.4A17 P21 I22 K251A17-N24 WeakPolarHBondContact CB-ND2 3.5Å; P21-N24 PolarHBondContact O-N 3.44Å; I22-N24 PolarHBondContact O-N 3.36Å; N24-K251 PolarHBondContact O-NZ 3.18Å
25G97.2Very high97.4Very high11 Ų1145 Ų4511%0.11325%0.253CS..  trans-61.8162.8-175.800000114.1I22 R27 E204 K251I22-G25 WeakPolarHBondContact O-CA 3.37Å; I22-G25 PolarHBondContact O-N 3Å; G25-R27 VanDerWaalsContact C-N 3.25Å; G25-R27 PolarHBondContact O-N 3.21Å; G25-E204 VanDerWaalsContact CA-OE1 3.23Å; G25-E204 WeakPolarHBondContact CA-OE1 3.48Å; G25-K251 PolarHBondContact O-NZ 2.85Å
26P97.7Very high97.3Very high80 Ų8044.7 Ų44.752%0.51927%0.273SS..THydrogen-bonded Turntrans-68.5-17.5-172.928.5-35.7000115E204 K251P26-E204 WeakPolarHBondContact CD-OE1 3.42Å; P26-K251 HydrophobicContact CB-CD 4.49Å; P26-K251 WeakPolarHBondContact O-CD 3.17Å
27R98.1Very high97.3Very high73 Ų7350.4 Ų50.428%0.27530%0.304SS..THydrogen-bonded Turntrans-13237.8-172.1-54.6-177.3-66.7156.56.6112.3G25 G195 S196 E204 R253G25-R27 VanDerWaalsContact C-N 3.25Å; G25-R27 PolarHBondContact O-N 3.21Å; R27-G195 CarbonylContact O-C 3.55Å; R27-G195 WeakPolarHBondContact O-CA 3.41Å; R27-S196 PolarHBondContact O-N 3.31Å; R27-E204 WeakPolarHBondContact CA-OE1 3.41Å; R27-E204 HydrophobicContact CB-CB 4.42Å; R27-E204 HydrophobicContact CB-CG 4.21Å; R27-E204 PolarHBondContact N-OE1 3.38Å; R27-E204 IonicContact NE-OE2 3.98Å; R27-E204 PolarHBondContact NE-OE2 3.45Å; R27-E204 PolarHBondContact NH2-O 3.46Å; R27-E204 IonicContact NH2-OE2 3.02Å; R27-R253 HydrophobicContact CG-CG 4.37Å; R27-R253 PolarHBondContact O-NH1 2.95Å
28Q98.8Very high97.4Very high4 Ų450 Ų502%0.01930%0.302CS..  trans-70.7149.3178.7-68.8-71.9-67.600112.8I22 A23 S196 L202 Q248 R253I22-Q28 WeakPolarHBondContact O-CG 3.39Å; I22-Q28 PolarHBondContact O-NE2 3.28Å; I22-Q28 PolarHBondContact O-OE1 3.15Å; A23-Q28 WeakPolarHBondContact O-CG 3.45Å; Q28-S196 WeakPolarHBondContact CA-OG 3.42Å; Q28-S196 PolarHBondContact NE2-OG 3.3Å; Q28-L202 PolarHBondContact NE2-O 3.03Å; Q28-Q248 HydrophobicContact CB-CB 3.95Å; Q28-Q248 HydrophobicContact CB-CG 3.93Å; Q28-R253 PolarHBondContact O-NH1 3.33Å; Q28-R253 PolarHBondContact O-NH2 3.31Å
29S98.9Very high97.5Very high0 Ų046.8 Ų46.80%029%0.289CS..SBendtrans-118.8158.7176.2-67.30000110.6Y193 G195 S196 W208 R245S29-Y193 WeakPolarHBondContact CB-OH 3.39Å; S29-Y193 WeakPolarHBondContact OG-CE2 3.3Å; S29-Y193 PolarHBondContact OG-OH 3.14Å; S29-G195 VanDerWaalsContact OG-CA 3.29Å; S29-G195 WeakPolarHBondContact OG-CA 3.14Å; S29-S196 WeakPolarHBondContact CB-O 3.47Å; S29-S196 PolarHBondContact N-OG 3Å; S29-S196 PolarHBondContact OG-N 2.72Å; S29-W208 PolarHBondContact OG-NE1 3.26Å; S29-R245 WeakPolarHBondContact O-CD 2.98Å; S29-R245 PolarHBondContact O-NH1 3.42Å
30P98.9Very high97.6Very high0 Ų049.5 Ų49.50%029%0.293CS..  cis-76.5-179.6-2.135.1-39.4000112.5E106 T198 R245 Q248P30-E106 HydrophobicContact CB-CB 3.79Å; P30-E106 WeakPolarHBondContact CB-O 3.38Å; P30-E106 VanDerWaalsContact CG-C 3.48Å; P30-E106 HydrophobicContact CG-CB 3.69Å; P30-E106 HydrophobicContact CG-CG 4.39Å; P30-E106 WeakPolarHBondContact CG-O 3.45Å; P30-T198 HydrophobicContact CB-CG2 4.45Å; P30-R245 VanDerWaalsContact CG-O 3.31Å; P30-R245 WeakPolarHBondContact CG-O 3.21Å; P30-Q248 WeakPolarHBondContact O-CB 3.39Å; P30-Q248 PolarHBondContact O-N 2.78Å
31I98.9Very high97.7Very high1 Ų149.4 Ų49.41%0.00529%0.294CS..  trans-132.7161.4174.161.1168.5000111.1I33 T108 Y193 L250 V255I31-I33 HydrophobicContact CD1-CG1 4.33Å; I31-I33 HydrophobicContact CG1-CG1 4.25Å; I31-T108 PolarHBondContact O-N 3.23Å; I31-Y193 HydrophobicContact CD1-CD1 3.73Å; I31-Y193 HydrophobicContact CD1-CD2 3.88Å; I31-Y193 HydrophobicContact CD1-CE1 3.72Å; I31-Y193 HydrophobicContact CD1-CE2 3.88Å; I31-Y193 HydrophobicContact CD1-CG 3.82Å; I31-Y193 HydrophobicContact CG1-CD1 4.33Å; I31-Y193 HydrophobicContact CG1-CE1 3.79Å; I31-Y193 HydrophobicContact CG1-CE2 4.07Å; I31-Y193 HydrophobicContact CG2-CE2 4.15Å; I31-L250 HydrophobicContact CD1-CD1 3.62Å; I31-L250 HydrophobicContact CG2-CD1 4.35Å; I31-V255 HydrophobicContact CD1-CG2 3.59Å
32N98.9Very high97.7Very high56 Ų5649.2 Ų49.230%0.29929%0.293SS..EExtended strand (participates in β ladder)trans-80.9117.5161.7177.851000109.5V34 T108 A110 G111N32-V34 VanDerWaalsContact ND2-CG2 3.34Å; N32-V34 WeakPolarHBondContact ND2-CG2 3.25Å; N32-T108 WeakPolarHBondContact CA-OG1 3.15Å; N32-T108 VanDerWaalsContact CB-OG1 3.26Å; N32-T108 WeakPolarHBondContact CB-OG1 3.31Å; N32-T108 VanDerWaalsContact CG-OG1 3.3Å; N32-T108 PolarHBondContact OD1-O 2.86Å; N32-T108 PolarHBondContact OD1-OG1 3.36Å; N32-A110 PolarHBondContact OD1-N 2.96Å; N32-G111 PolarHBondContact OD1-N 2.86Å
33I98.9Very high97.7Very high0 Ų050.2 Ų50.20%031%0.31CS..EExtended strand (participates in β ladder)trans-84.3118.3173.5-61.2169.5000107.7I31 P35 T108 V109 A110 W191 V210 V255I31-I33 HydrophobicContact CD1-CG1 4.33Å; I31-I33 HydrophobicContact CG1-CG1 4.25Å; I33-P35 WeakPolarHBondContact O-CD 3.36Å; I33-T108 PolarHBondContact N-O 2.8Å; I33-V109 CarbonylContact O-C 3.32Å; I33-V109 WeakPolarHBondContact O-CA 3.26Å; I33-A110 PolarHBondContact O-N 2.93Å; I33-W191 HydrophobicContact CD1-CB 4.21Å; I33-W191 HydrophobicContact CD1-CD2 4.32Å; I33-W191 HydrophobicContact CD1-CE3 4.05Å; I33-W191 HydrophobicContact CD1-CG 4.42Å; I33-W191 HydrophobicContact CG2-CD2 3.75Å; I33-W191 HydrophobicContact CG2-CE3 4.28Å; I33-W191 HydrophobicContact CG2-CG 3.85Å; I33-W191 HydrophobicContact CG2-CZ2 4.36Å; I33-V210 HydrophobicContact CD1-CB 4Å; I33-V210 HydrophobicContact CD1-CG1 3.98Å; I33-V210 HydrophobicContact CD1-CG2 4.16Å; I33-V255 HydrophobicContact CG2-CG1 4.31Å
34V98.4Very high97.8Very high52 Ų5250.9 Ų50.932%0.31531%0.313SS..  trans-101.8106173.3-1790000107.4N32 G36 D37 A38N32-V34 VanDerWaalsContact ND2-CG2 3.34Å; N32-V34 WeakPolarHBondContact ND2-CG2 3.25Å; V34-G36 PolarHBondContact O-N 3.13Å; V34-G36 VanDerWaalsContact O-N 3.16Å; V34-D37 HydrophobicContact CB-CB 4.15Å; V34-D37 HydrophobicContact CG1-CB 4.26Å; V34-D37 WeakPolarHBondContact CG1-OD2 3.39Å; V34-D37 PolarHBondContact O-N 3.05Å; V34-A38 PolarHBondContact O-N 3.33Å
35P96.8Very high97.8Very high56 Ų5650.7 Ų50.736%0.36431%0.307SS..G310 helixtrans-57-34.8-173.1-28.736.7000114I33 D37 A38 V109 W191I33-P35 WeakPolarHBondContact O-CD 3.36Å; P35-D37 VanDerWaalsContact C-N 3.26Å; P35-D37 PolarHBondContact O-N 3.37Å; P35-A38 PolarHBondContact O-N 2.66Å; P35-V109 HydrophobicContact CG-CG1 3.62Å; P35-W191 HydrophobicContact CB-CZ2 4.34Å; P35-W191 HydrophobicContact CG-CZ2 4Å
36G95.9Very high97.8Very high75 Ų7555.3 Ų55.377%0.77334%0.335SS*.G310 helixtrans-68.8-19.7177.300000114.9V34V34-G36 PolarHBondContact O-N 3.13Å; V34-G36 VanDerWaalsContact O-N 3.16Å
37D96.9Very high97.8Very high126 Ų12652.3 Ų52.367%0.67431%0.314SS*.G310 helixtrans-99.6-7.8176.4-61.2-24.5000111.9V34 P35V34-D37 HydrophobicContact CB-CB 4.15Å; V34-D37 HydrophobicContact CG1-CB 4.26Å; V34-D37 WeakPolarHBondContact CG1-OD2 3.39Å; V34-D37 PolarHBondContact O-N 3.05Å; P35-D37 VanDerWaalsContact C-N 3.26Å; P35-D37 PolarHBondContact O-N 3.37Å
38A97.4Very high97.8Very high18 Ų1852.1 Ų52.115%0.14932%0.321CS..SBendtrans-77.3131.7176.700000109.9V34 P35 V255 A257V34-A38 PolarHBondContact O-N 3.33Å; P35-A38 PolarHBondContact O-N 2.66Å; A38-V255 WeakPolarHBondContact CA-O 3.48Å; A38-V255 HydrophobicContact CB-CB 4.34Å; A38-V255 HydrophobicContact CB-CG1 4.2Å; A38-A257 HydrophobicContact CB-CB 4.47Å
39S97.5Very high97.8Very high64 Ų6453 Ų5345%0.44833%0.325SS..EExtended strand (participates in β ladder)trans-89.2119.6-179.6-650000110.3D41 V255 R256 A257S39-D41 PolarHBondContact O-N 3.08Å; S39-V255 PolarHBondContact N-O 3.01Å; S39-R256 CarbonylContact O-C 3.09Å; S39-R256 VanDerWaalsContact O-CA 3.24Å; S39-R256 WeakPolarHBondContact O-CA 3.39Å; S39-A257 PolarHBondContact O-N 2.74Å
40Y98.1Very high97.7Very high105 Ų10559.2 Ų59.241%0.41235%0.352SS..EExtended strand (participates in β ladder)trans-59.3125.4167.6172.2-119.8000109.8P42 A257 F259 Q260Y40-P42 HydrophobicContact CE1-CB 3.85Å; Y40-P42 HydrophobicContact CE1-CG 4.37Å; Y40-A257 WeakPolarHBondContact CD2-O 3.35Å; Y40-F259 WeakPolarHBondContact CD2-O 3.47Å; Y40-Q260 HydrophobicContact CD1-CG 3.68Å; Y40-Q260 HydrophobicContact CD2-CG 4.11Å; Y40-Q260 HydrophobicContact CE1-CG 3.72Å; Y40-Q260 HydrophobicContact CE2-CG 4.14Å; Y40-Q260 HydrophobicContact CG-CG 3.87Å
41D98Very high97.7Very high36 Ų3659.8 Ų59.819%0.19336%0.355CS..  trans-117.4102.2178.4-178.9-2.4000109.3S39 A43 L44 R256 A257S39-D41 PolarHBondContact O-N 3.08Å; D41-A43 PolarHBondContact O-N 2.8Å; D41-A43 VanDerWaalsContact O-N 3.12Å; D41-A43 VanDerWaalsContact OD1-CB 3.27Å; D41-A43 WeakPolarHBondContact OD1-CB 3.38Å; D41-A43 PolarHBondContact OD1-N 3.42Å; D41-L44 HydrophobicContact CB-CD1 3.93Å; D41-L44 HydrophobicContact CB-CG 3.89Å; D41-L44 WeakPolarHBondContact O-CB 3.35Å; D41-L44 PolarHBondContact O-N 3.12Å; D41-R256 HydrophobicContact CB-CB 4.2Å; D41-R256 HydrophobicContact CB-CG 4.48Å; D41-R256 WeakPolarHBondContact OD2-CD 3.35Å; D41-R256 IonicContact OD2-CZ 2.71Å; D41-R256 IonicContact OD2-NE 2.77Å; D41-R256 IonicContact OD2-NH1 3.64Å; D41-R256 PolarHBondContact OD2-NH1 2.71Å; D41-A257 PolarHBondContact N-O 3.47Å
42P96.6Very high97.6Very high98 Ų9862.5 Ų62.564%0.63637%0.369SS*.THydrogen-bonded Turntrans-68.1-9.1-179.229.3-35.7000113.6Y40 L44Y40-P42 HydrophobicContact CE1-CB 3.85Å; Y40-P42 HydrophobicContact CE1-CG 4.37Å; P42-L44 VanDerWaalsContact C-N 3.34Å
43A97.1Very high97.6Very high80 Ų8062 Ų6266%0.66137%0.369SS*.THydrogen-bonded Turntrans-82.7-14173.500000112.6D41 K45D41-A43 PolarHBondContact O-N 2.8Å; D41-A43 VanDerWaalsContact O-N 3.12Å; D41-A43 VanDerWaalsContact OD1-CB 3.27Å; D41-A43 WeakPolarHBondContact OD1-CB 3.38Å; D41-A43 PolarHBondContact OD1-N 3.42Å; A43-K45 PolarHBondContact O-N 3.39Å
44L98Very high97.5Very high18 Ų1865.5 Ų65.59%0.09439%0.394CS..PPolyproline II helixtrans-66.4119.6173.1-74.8177.9000110D41 P42 P83 Y190 T192 R256D41-L44 HydrophobicContact CB-CD1 3.93Å; D41-L44 HydrophobicContact CB-CG 3.89Å; D41-L44 WeakPolarHBondContact O-CB 3.35Å; D41-L44 PolarHBondContact O-N 3.12Å; P42-L44 VanDerWaalsContact C-N 3.34Å; L44-P83 HydrophobicContact CD2-CB 3.9Å; L44-Y190 WeakPolarHBondContact CB-OH 3.26Å; L44-Y190 HydrophobicContact CD1-CE2 4.1Å; L44-Y190 HydrophobicContact CD2-CE2 4.29Å; L44-T192 HydrophobicContact CD1-CG2 3.75Å; L44-T192 HydrophobicContact CD2-CG2 3.96Å; L44-R256 HydrophobicContact CD1-CB 3.96Å
45K96.8Very high97.4Very high112 Ų11263.4 Ų63.449%0.48738%0.381SS..PPolyproline II helixtrans-79.3164.6177.2-64.2179.9-175.5178.90111A43 D81 G82 Y190A43-K45 PolarHBondContact O-N 3.39Å; K45-D81 HydrophobicContact CB-CB 4.12Å; K45-D81 HydrophobicContact CD-CB 4.02Å; K45-D81 WeakPolarHBondContact CD-OD1 3.5Å; K45-D81 IonicContact NZ-OD1 2.83Å; K45-D81 PolarHBondContact NZ-OD1 3.25Å; K45-G82 WeakPolarHBondContact O-CA 3.39Å; K45-Y190 PolarHBondContact O-OH 3.2Å
46P97.4Very high97.5Very high108 Ų10860.9 Ų60.970%0.70137%0.365SS*.PPolyproline II helixtrans-57.5150.2161.6-23.134.9000111.4D81 G82P46-D81 WeakPolarHBondContact O-CB 3.4Å; P46-G82 PolarHBondContact O-N 2.77Å
47L97.6Very high97.6Very high16 Ų1661 Ų618%0.08435%0.347CS..EExtended strand (participates in β ladder)trans-73.2136.5171.8-61.8169.1000109.8L49 L79 L188 Y190 I209L47-L49 HydrophobicContact CB-CG 4.49Å; L47-L79 HydrophobicContact CD2-CD1 4Å; L47-L188 HydrophobicContact CB-CD1 4.48Å; L47-L188 HydrophobicContact CD1-CB 4.42Å; L47-Y190 HydrophobicContact CD1-CD1 3.79Å; L47-Y190 HydrophobicContact CD1-CE1 4.23Å; L47-Y190 HydrophobicContact CD1-CG 4.31Å; L47-Y190 HydrophobicContact CD2-CD1 4.32Å; L47-Y190 HydrophobicContact CD2-CE1 4.02Å; L47-Y190 HydrophobicContact CG-CD1 3.81Å; L47-Y190 HydrophobicContact CG-CE1 3.72Å; L47-I209 HydrophobicContact CD1-CG2 3.52Å; L47-I209 HydrophobicContact CD2-CD1 3.91Å; L47-I209 HydrophobicContact CD2-CG1 4.43Å; L47-I209 HydrophobicContact CD2-CG2 3.81Å; L47-I209 HydrophobicContact CG-CG2 4.27Å
48V97.9Very high97.7Very high69 Ų6957.8 Ų57.842%0.41833%0.328SS..EExtended strand (participates in β ladder)trans-112.4101.1172178.20000108K80 D81V48-K80 HydrophobicContact CB-CB 4.12Å; V48-K80 HydrophobicContact CG1-CB 4.46Å; V48-K80 PolarHBondContact N-O 3.04Å; V48-K80 PolarHBondContact O-N 3.24Å; V48-D81 HydrophobicContact CG2-CB 4.13Å
49L98Very high97.8Very high22 Ų2256.9 Ų56.912%0.11532%0.321CS..EExtended strand (participates in β ladder)trans-106.4130.8179.3-65.8168.8000108.7L47 Y51 L79 L184 L188L47-L49 HydrophobicContact CB-CG 4.49Å; L49-Y51 HydrophobicContact CB-CE2 4.31Å; L49-Y51 WeakPolarHBondContact CD2-OH 3.09Å; L49-L79 HydrophobicContact CD2-CB 3.79Å; L49-L79 HydrophobicContact CD2-CD1 3.49Å; L49-L79 VanDerWaalsContact CD2-CD1 3.49Å; L49-L79 HydrophobicContact CD2-CG 4.16Å; L49-L79 HydrophobicContact CG-CD1 4.29Å; L49-L184 HydrophobicContact CD1-CD1 3.42Å; L49-L184 VanDerWaalsContact CD1-CD1 3.42Å; L49-L184 HydrophobicContact CD1-CD2 4.29Å; L49-L188 HydrophobicContact CD1-CD1 4.24Å
50K97.4Very high97.8Very high131 Ų13155.4 Ų55.457%0.5731%0.308SS*.EExtended strand (participates in β ladder)trans-139.1119175.1178.9-169.6173.5-166.90108S77 T78K50-S77 CarbonylContact O-C 3.53Å; K50-S77 VanDerWaalsContact O-CA 3.29Å; K50-S77 WeakPolarHBondContact O-CA 3.39Å; K50-T78 PolarHBondContact N-O 2.99Å; K50-T78 PolarHBondContact O-N 3.34Å
51Y98.3Very high97.8Very high13 Ų1350.4 Ų50.45%0.05129%0.288CS..  trans-123.1131.6-179.7-57.2-48.2000111.3L49 L90 H122 N179 P180 E181L49-Y51 HydrophobicContact CB-CE2 4.31Å; L49-Y51 WeakPolarHBondContact CD2-OH 3.09Å; Y51-L90 HydrophobicContact CD1-CB 4.4Å; Y51-L90 HydrophobicContact CD1-CD2 3.94Å; Y51-L90 HydrophobicContact CE1-CB 4.07Å; Y51-L90 HydrophobicContact CE1-CD2 3.94Å; Y51-L90 HydrophobicContact CE1-CG 4.42Å; Y51-H122 AromaticContact CE1-NE2 3.48Å; Y51-H122 WeakPolarHBondContact CE1-NE2 3.31Å; Y51-H122 AromaticContact CZ-NE2 3.57Å; Y51-H122 PolarHBondContact OH-CE1 3.07Å; Y51-H122 PolarHBondContact OH-NE2 3.17Å; Y51-N179 WeakPolarHBondContact CB-OD1 3.07Å; Y51-P180 HydrophobicContact CD1-CG 4.33Å; Y51-P180 HydrophobicContact CD2-CB 4.24Å; Y51-P180 HydrophobicContact CD2-CG 3.59Å; Y51-P180 HydrophobicContact CE2-CB 4.31Å; Y51-P180 HydrophobicContact CE2-CG 3.99Å; Y51-P180 HydrophobicContact CG-CG 3.75Å; Y51-E181 HydrophobicContact CD2-CB 3.98Å
52D98.1Very high97.8Very high58 Ų5850.8 Ų50.831%0.3129%0.29SS..  trans-94.4111.8172.6-175.5-20.4000108.7S54 T55 S77D52-S54 PolarHBondContact O-N 2.91Å; D52-S54 VanDerWaalsContact O-N 3.11Å; D52-S54 WeakPolarHBondContact OD1-CB 3.45Å; D52-S54 PolarHBondContact OD1-N 3.06Å; D52-S54 PolarHBondContact OD1-OG 2.89Å; D52-S54 PolarHBondContact OD2-OG 3.29Å; D52-T55 HydrophobicContact CB-CG2 3.98Å; D52-T55 WeakPolarHBondContact O-CB 3.49Å; D52-T55 PolarHBondContact O-N 2.89Å; D52-T55 PolarHBondContact O-OG1 3.47Å; D52-S77 PolarHBondContact N-OG 3.34Å; D52-S77 PolarHBondContact O-OG 3.38Å
53P97.6Very high97.9Very high44 Ų4446.3 Ų46.329%0.28626%0.262SS..G310 helixtrans-60-26.5-176.2-22.634.8000113.5T55 C56 D177 F178 N179P53-T55 PolarHBondContact O-N 2.87Å; P53-C56 VanDerWaalsContact O-CB 3.32Å; P53-C56 WeakPolarHBondContact O-CB 3.43Å; P53-C56 PolarHBondContact O-N 2.88Å; P53-D177 VanDerWaalsContact O-CA 3.3Å; P53-D177 WeakPolarHBondContact O-CA 3.36Å; P53-D177 PolarHBondContact O-N 3.31Å; P53-F178 WeakPolarHBondContact CA-O 3.09Å; P53-F178 PolarHBondContact O-N 2.85Å; P53-N179 HydrophobicContact CB-CB 4.37Å; P53-N179 HydrophobicContact CG-CB 3.8Å
54S97.4Very high97.9Very high75 Ų7544.7 Ų44.752%0.52424%0.24SC..G310 helixtrans-69.8-14.2179.571.80000113.2D52 C56D52-S54 PolarHBondContact O-N 2.91Å; D52-S54 VanDerWaalsContact O-N 3.11Å; D52-S54 WeakPolarHBondContact OD1-CB 3.45Å; D52-S54 PolarHBondContact OD1-N 3.06Å; D52-S54 PolarHBondContact OD1-OG 2.89Å; D52-S54 PolarHBondContact OD2-OG 3.29Å; S54-C56 VanDerWaalsContact C-N 3.28Å
55T97.7Very high97.9Very high7 Ų744.1 Ų44.14%0.04324%0.237CC..G310 helixtrans-79-10.9174.460.90000113.1D52 P53 F70 L71 S77D52-T55 HydrophobicContact CB-CG2 3.98Å; D52-T55 WeakPolarHBondContact O-CB 3.49Å; D52-T55 PolarHBondContact O-N 2.89Å; D52-T55 PolarHBondContact O-OG1 3.47Å; P53-T55 PolarHBondContact O-N 2.87Å; T55-F70 CarbonylContact O-C 3.44Å; T55-F70 VanDerWaalsContact O-CA 3.23Å; T55-F70 WeakPolarHBondContact O-CA 3.49Å; T55-L71 PolarHBondContact O-N 3.35Å; T55-S77 PolarHBondContact OG1-OG 2.87Å
56C98.3Very high98Very high4 Ų438.8 Ų38.83%0.02721%0.214CC..EExtended strand (participates in β ladder)trans-70.3129.3176.8-163.50000110.5P53 S54 V68 F70 F175 F178P53-C56 VanDerWaalsContact O-CB 3.32Å; P53-C56 WeakPolarHBondContact O-CB 3.43Å; P53-C56 PolarHBondContact O-N 2.88Å; S54-C56 VanDerWaalsContact C-N 3.28Å; C56-V68 WeakPolarHBondContact SG-CG1 3.5Å; C56-F70 HydrophobicContact CB-CD1 3.95Å; C56-F70 HydrophobicContact CB-CE1 3.57Å; C56-F70 HydrophobicContact CB-CZ 4.2Å; C56-F175 CarbonylContact C-O 3.57Å; C56-F175 PolarHBondContact SG-O 3.16Å; C56-F178 HydrophobicContact CB-CB 4.17Å
57L98Very high98Very high76 Ų7635.8 Ų35.840%0.39819%0.191SC..EExtended strand (participates in β ladder)trans-109.8-59.9-170.8-58.9178.7000112.6T69 L71 F175L57-T69 HydrophobicContact CD1-CG2 4.49Å; L57-T69 PolarHBondContact N-O 3.2Å; L57-L71 HydrophobicContact CD1-CB 4.26Å; L57-L71 HydrophobicContact CD2-CB 4.32Å; L57-L71 HydrophobicContact CG-CB 4.46Å; L57-F175 CarbonylContact C-O 3.44Å; L57-F175 PolarHBondContact N-O 2.96Å; L57-F175 PolarHBondContact O-N 3.37Å
58E98.4Very high98.1Very high59 Ų5935 Ų3528%0.27619%0.187SC..EExtended strand (participates in β ladder)trans-153.7159-16765.7-176179.300111.4V68 T69 Q172 C173E58-V68 WeakPolarHBondContact O-CA 3.46Å; E58-T69 PolarHBondContact O-N 3.02Å; E58-Q172 PolarHBondContact OE2-NE2 3.09Å; E58-C173 WeakPolarHBondContact CA-O 3.34Å; E58-C173 WeakPolarHBondContact CB-O 3.24Å
59I98.8Very high98.1Very high0 Ų032.5 Ų32.50%017%0.172CC..EExtended strand (participates in β ladder)trans-117.1132.5166.9-170.5178.7000108.5F66 Q67 V68 L159 E162 I166 Q172 C173 F175I59-F66 HydrophobicContact CD1-CD2 3.83Å; I59-F66 HydrophobicContact CD1-CE2 4.4Å; I59-F66 HydrophobicContact CD1-CG 4.46Å; I59-F66 HydrophobicContact CG1-CB 4.49Å; I59-F66 HydrophobicContact CG1-CD2 4.13Å; I59-Q67 WeakPolarHBondContact CA-O 3.39Å; I59-V68 HydrophobicContact CB-CG2 4.11Å; I59-V68 HydrophobicContact CD1-CG2 4.13Å; I59-V68 HydrophobicContact CG1-CG2 3.83Å; I59-L159 HydrophobicContact CD1-CD2 4.24Å; I59-E162 HydrophobicContact CD1-CB 4.4Å; I59-E162 HydrophobicContact CG2-CB 4.17Å; I59-E162 HydrophobicContact CG2-CG 4.47Å; I59-I166 HydrophobicContact CD1-CD1 3.71Å; I59-I166 HydrophobicContact CD1-CG1 4.48Å; I59-I166 HydrophobicContact CG1-CD1 3.83Å; I59-I166 HydrophobicContact CG2-CG2 4.09Å; I59-Q172 VanDerWaalsContact O-CA 3.26Å; I59-Q172 WeakPolarHBondContact O-CA 3.48Å; I59-C173 WeakPolarHBondContact CG2-SG 3.4Å; I59-C173 PolarHBondContact N-O 3.35Å; I59-C173 PolarHBondContact O-N 3.48Å; I59-F175 HydrophobicContact CB-CB 3.95Å; I59-F175 HydrophobicContact CB-CG 4.19Å; I59-F175 HydrophobicContact CG2-CB 3.86Å; I59-F175 HydrophobicContact CG2-CD2 4.35Å; I59-F175 HydrophobicContact CG2-CG 4.21Å
60L98.7Very high98.2Very high33 Ų3331.5 Ų31.517%0.17317%0.166CC..EExtended strand (participates in β ladder)trans-133.1132.9-174.916468.8000109.5N62 F66 Q67 Q172L60-N62 HydrophobicContact CD2-CB 4.34Å; L60-N62 HydrophobicContact CG-CB 4.4Å; L60-F66 CarbonylContact O-C 3.45Å; L60-F66 WeakPolarHBondContact O-CA 3.39Å; L60-Q67 PolarHBondContact N-O 2.76Å; L60-Q67 PolarHBondContact O-N 3.2Å; L60-Q172 HydrophobicContact CB-CB 4.13Å; L60-Q172 HydrophobicContact CD1-CB 3.88Å
61N98.8Very high98.2Very high0 Ų028.7 Ų28.70%016%0.157CC..EExtended strand (participates in β ladder)trans-85.6110.7160.9177.9-17.2000109.1G63 I166 K167 T168 D170 S171 L229 M240N61-G63 VanDerWaalsContact C-N 3.32Å; N61-G63 WeakPolarHBondContact OD1-CA 3.32Å; N61-G63 PolarHBondContact OD1-N 3.11Å; N61-I166 HydrophobicContact CB-CB 4.24Å; N61-I166 HydrophobicContact CB-CD1 4.38Å; N61-I166 WeakPolarHBondContact CB-O 3.45Å; N61-I166 PolarHBondContact ND2-O 3.15Å; N61-I166 VanDerWaalsContact ND2-O 3.11Å; N61-K167 PolarHBondContact ND2-O 2.97Å; N61-K167 VanDerWaalsContact ND2-O 3.15Å; N61-T168 WeakPolarHBondContact CB-O 3.49Å; N61-T168 VanDerWaalsContact ND2-C 3.32Å; N61-T168 PolarHBondContact ND2-O 3.46Å; N61-D170 WeakPolarHBondContact O-CA 3.24Å; N61-D170 PolarHBondContact O-N 3.14Å; N61-S171 PolarHBondContact N-O 2.55Å; N61-L229 PolarHBondContact ND2-O 2.86Å; N61-L229 VanDerWaalsContact ND2-O 3.09Å; N61-M240 VanDerWaalsContact OD1-CE 3.26Å; N61-M240 WeakPolarHBondContact OD1-CE 3.49Å
62N97.6Very high98.2Very high44 Ų4429.3 Ų29.324%0.23516%0.162CC..  trans-91.58.5-177.36818.3000113.5L60 H64 S65L60-N62 HydrophobicContact CD2-CB 4.34Å; L60-N62 HydrophobicContact CG-CB 4.4Å; N62-H64 VanDerWaalsContact C-N 3.29Å; N62-H64 PolarHBondContact O-N 3.39Å; N62-H64 WeakPolarHBondContact OD1-CA 3.46Å; N62-H64 WeakPolarHBondContact OD1-CB 3.49Å; N62-H64 PolarHBondContact OD1-N 3.27Å; N62-S65 PolarHBondContact N-O 3.24Å; N62-S65 PolarHBondContact OD1-N 3.46Å; N62-S65 PolarHBondContact OD1-O 3.16Å
63G97.6Very high98.1Very high4 Ų431.1 Ų31.14%0.04117%0.171CC..SBendtrans76.810.6-176.400000114.7N61 F230N61-G63 VanDerWaalsContact C-N 3.32Å; N61-G63 WeakPolarHBondContact OD1-CA 3.32Å; N61-G63 PolarHBondContact OD1-N 3.11Å; G63-F230 VanDerWaalsContact O-CD1 3.25Å; G63-F230 WeakPolarHBondContact O-CD1 3.44Å
64H97.5Very high98Very high46 Ų4633.6 Ų33.621%0.21318%0.181CC..SBendtrans-136-29.4174.4-57.5-62.6000112.4W5 N62 N243W5-H64 HydrophobicContact CH2-CB 3.9Å; W5-H64 AromaticContact CH2-CD2 3.99Å; W5-H64 AromaticContact CH2-CG 3.62Å; W5-H64 AromaticContact CH2-ND1 3.82Å; W5-H64 HydrophobicContact CZ2-CB 4.49Å; W5-H64 AromaticContact CZ2-CD2 3.74Å; W5-H64 AromaticContact CZ2-CG 3.86Å; W5-H64 AromaticContact CZ2-NE2 3.92Å; W5-H64 AromaticContact CZ3-ND1 3.92Å; W5-H64 PolarHBondContact O-CE1 3.27Å; W5-H64 VanDerWaalsContact O-CE1 3.29Å; N62-H64 VanDerWaalsContact C-N 3.29Å; N62-H64 PolarHBondContact O-N 3.39Å; N62-H64 WeakPolarHBondContact OD1-CA 3.46Å; N62-H64 WeakPolarHBondContact OD1-CB 3.49Å; N62-H64 PolarHBondContact OD1-N 3.27Å; H64-N243 WeakPolarHBondContact O-CB 3.27Å; H64-N243 PolarHBondContact O-ND2 2.87Å
65S98.4Very high98Very high5 Ų533.5 Ų33.54%0.03518%0.175CC..SBendtrans-156.1175.3169.2-179.60000107.8N62 F95 M240N62-S65 PolarHBondContact N-O 3.24Å; N62-S65 PolarHBondContact OD1-N 3.46Å; N62-S65 PolarHBondContact OD1-O 3.16Å; S65-F95 PolarHBondContact OG-N 2.82Å; S65-F95 PolarHBondContact OG-O 3.37Å; S65-M240 WeakPolarHBondContact CA-SD 3.18Å
66F98.4Very high97.9Very high0 Ų034.2 Ų34.20%018%0.18CC..EExtended strand (participates in β ladder)trans-83.8151.4148.972.1-89.2000110.6I59 L60 F93 H94 F95 W97 L159 F163 I166 F225 L228I59-F66 HydrophobicContact CD1-CD2 3.83Å; I59-F66 HydrophobicContact CD1-CE2 4.4Å; I59-F66 HydrophobicContact CD1-CG 4.46Å; I59-F66 HydrophobicContact CG1-CB 4.49Å; I59-F66 HydrophobicContact CG1-CD2 4.13Å; L60-F66 CarbonylContact O-C 3.45Å; L60-F66 WeakPolarHBondContact O-CA 3.39Å; F66-F93 HydrophobicContact CE2-CE2 4.4Å; F66-H94 WeakPolarHBondContact O-CB 3.39Å; F66-F95 HydrophobicContact CE1-CB 4.39Å; F66-F95 AromaticContact CE1-CD2 3.99Å; F66-F95 HydrophobicContact CE1-CD2 3.99Å; F66-F95 HydrophobicContact CE1-CG 4.46Å; F66-F95 AromaticContact CE2-CD2 3.68Å; F66-F95 HydrophobicContact CE2-CD2 3.68Å; F66-F95 AromaticContact CE2-CE2 3.86Å; F66-F95 HydrophobicContact CE2-CE2 3.86Å; F66-F95 HydrophobicContact CZ-CB 4.42Å; F66-F95 AromaticContact CZ-CD2 3.21Å; F66-F95 HydrophobicContact CZ-CD2 3.21Å; F66-F95 AromaticContact CZ-CE2 3.57Å; F66-F95 HydrophobicContact CZ-CE2 3.57Å; F66-F95 HydrophobicContact CZ-CG 4.04Å; F66-W97 AromaticContact CD1-CH2 3.85Å; F66-W97 HydrophobicContact CD1-CH2 3.85Å; F66-W97 AromaticContact CD1-CZ3 3.99Å; F66-W97 HydrophobicContact CD1-CZ3 3.99Å; F66-W97 HydrophobicContact CE1-CH2 4.22Å; F66-W97 AromaticContact CE1-CZ3 3.98Å; F66-W97 HydrophobicContact CE1-CZ3 3.98Å; F66-L159 HydrophobicContact CE2-CD2 4.49Å; F66-F163 AromaticContact CD1-CE1 3.98Å; F66-F163 HydrophobicContact CD1-CE1 3.98Å; F66-F163 HydrophobicContact CD1-CZ 4Å; F66-F163 HydrophobicContact CD2-CE1 4.42Å; F66-F163 AromaticContact CE1-CE1 3.81Å; F66-F163 HydrophobicContact CE1-CE1 3.81Å; F66-F163 HydrophobicContact CE1-CE2 4.49Å; F66-F163 AromaticContact CE1-CZ 3.48Å; F66-F163 HydrophobicContact CE1-CZ 3.48Å; F66-F163 VanDerWaalsContact CE1-CZ 3.48Å; F66-F163 HydrophobicContact CE2-CE1 4.26Å; F66-F163 HydrophobicContact CG-CE1 4.27Å; F66-F163 AromaticContact CZ-CE1 3.94Å; F66-F163 HydrophobicContact CZ-CE1 3.94Å; F66-F163 AromaticContact CZ-CZ 3.77Å; F66-F163 HydrophobicContact CZ-CZ 3.77Å; F66-I166 HydrophobicContact CB-CD1 3.55Å; F66-I166 HydrophobicContact CG-CD1 4.33Å; F66-F225 AromaticContact CE1-CD1 3.79Å; F66-F225 HydrophobicContact CE1-CD1 3.79Å; F66-F225 AromaticContact CE1-CE1 3.57Å; F66-F225 HydrophobicContact CE1-CE1 3.57Å; F66-F225 HydrophobicContact CE1-CZ 4.25Å; F66-F225 HydrophobicContact CZ-CD1 4.4Å; F66-F225 AromaticContact CZ-CE1 3.72Å; F66-F225 HydrophobicContact CZ-CE1 3.72Å; F66-F225 HydrophobicContact CZ-CZ 4.09Å; F66-L228 HydrophobicContact CB-CD1 4.21Å; F66-L228 HydrophobicContact CD1-CD1 3.6Å; F66-L228 HydrophobicContact CE1-CD1 4.43Å; F66-L228 HydrophobicContact CG-CD1 4.31Å
67Q98.5Very high97.9Very high45 Ų4534.1 Ų34.121%0.2118%0.18CC..EExtended strand (participates in β ladder)trans-133.6133.3178.9-176.7-173.2-74.600109.1I59 L60 T69 Q92 F93I59-Q67 WeakPolarHBondContact CA-O 3.39Å; L60-Q67 PolarHBondContact N-O 2.76Å; L60-Q67 PolarHBondContact O-N 3.2Å; Q67-T69 PolarHBondContact NE2-OG1 3.22Å; Q67-Q92 HydrophobicContact CG-CB 3.69Å; Q67-Q92 HydrophobicContact CG-CG 4.06Å; Q67-F93 WeakPolarHBondContact CA-O 3.44Å
68V98.8Very high98Very high0 Ų030.7 Ų30.70%016%0.162CC..EExtended strand (participates in β ladder)trans-102.4123.7168.51790000108.9C56 E58 I59 F70 Q92 F93 L159 F175C56-V68 WeakPolarHBondContact SG-CG1 3.5Å; E58-V68 WeakPolarHBondContact O-CA 3.46Å; I59-V68 HydrophobicContact CB-CG2 4.11Å; I59-V68 HydrophobicContact CD1-CG2 4.13Å; I59-V68 HydrophobicContact CG1-CG2 3.83Å; V68-F70 HydrophobicContact CB-CE2 4.31Å; V68-F70 HydrophobicContact CG1-CD2 4.47Å; V68-F70 HydrophobicContact CG1-CE2 3.68Å; V68-F70 HydrophobicContact CG1-CZ 4Å; V68-Q92 CarbonylContact O-C 3.49Å; V68-Q92 WeakPolarHBondContact O-CA 3.32Å; V68-Q92 WeakPolarHBondContact O-CB 3.14Å; V68-F93 HydrophobicContact CB-CD1 4.09Å; V68-F93 HydrophobicContact CB-CD2 4.28Å; V68-F93 HydrophobicContact CB-CE1 3.63Å; V68-F93 HydrophobicContact CB-CE2 3.81Å; V68-F93 HydrophobicContact CB-CG 4.39Å; V68-F93 HydrophobicContact CB-CZ 3.49Å; V68-F93 VanDerWaalsContact CB-CZ 3.49Å; V68-F93 HydrophobicContact CG1-CD1 4.48Å; V68-F93 HydrophobicContact CG1-CE1 3.79Å; V68-F93 HydrophobicContact CG1-CZ 3.93Å; V68-F93 HydrophobicContact CG2-CD2 4.38Å; V68-F93 HydrophobicContact CG2-CE1 4.08Å; V68-F93 HydrophobicContact CG2-CE2 3.55Å; V68-F93 HydrophobicContact CG2-CZ 3.39Å; V68-F93 PolarHBondContact N-O 2.99Å; V68-F93 PolarHBondContact O-N 2.96Å; V68-L159 HydrophobicContact CG2-CD2 3.71Å; V68-F175 HydrophobicContact CG1-CD1 3.77Å; V68-F175 HydrophobicContact CG1-CE1 4.17Å; V68-F175 HydrophobicContact CG2-CD1 4.19Å; V68-F175 HydrophobicContact CG2-CE1 4.25Å
69T98.7Very high98Very high17 Ų1727.9 Ų27.910%0.10415%0.149CC..EExtended strand (participates in β ladder)trans-102.3140.8-174.2-57.30000111.4L57 E58 Q67L57-T69 HydrophobicContact CD1-CG2 4.49Å; L57-T69 PolarHBondContact N-O 3.2Å; E58-T69 PolarHBondContact O-N 3.02Å; Q67-T69 PolarHBondContact NE2-OG1 3.22Å
70F98.6Very high97.9Very high0 Ų032.1 Ų32.10%017%0.167CC..EExtended strand (participates in β ladder)trans-118.9149.6177.9-65.6-100.4000111.4T55 C56 V68 L90 K91 F93 P180T55-F70 CarbonylContact O-C 3.44Å; T55-F70 VanDerWaalsContact O-CA 3.23Å; T55-F70 WeakPolarHBondContact O-CA 3.49Å; C56-F70 HydrophobicContact CB-CD1 3.95Å; C56-F70 HydrophobicContact CB-CE1 3.57Å; C56-F70 HydrophobicContact CB-CZ 4.2Å; V68-F70 HydrophobicContact CB-CE2 4.31Å; V68-F70 HydrophobicContact CG1-CD2 4.47Å; V68-F70 HydrophobicContact CG1-CE2 3.68Å; V68-F70 HydrophobicContact CG1-CZ 4Å; F70-L90 HydrophobicContact CB-CD2 4.38Å; F70-L90 HydrophobicContact CB-CG 4.42Å; F70-L90 HydrophobicContact CD1-CD2 3.89Å; F70-L90 HydrophobicContact CD2-CD2 3.67Å; F70-L90 HydrophobicContact CD2-CG 4.02Å; F70-L90 HydrophobicContact CE1-CD2 4.05Å; F70-L90 HydrophobicContact CE2-CD2 3.87Å; F70-L90 HydrophobicContact CG-CD2 3.7Å; F70-L90 HydrophobicContact CG-CG 4.16Å; F70-L90 HydrophobicContact CZ-CD2 4.05Å; F70-K91 PolarHBondContact N-O 3.08Å; F70-F93 AromaticContact CE2-CD1 3.56Å; F70-F93 HydrophobicContact CE2-CD1 3.56Å; F70-F93 AromaticContact CE2-CE1 3.69Å; F70-F93 HydrophobicContact CE2-CE1 3.69Å; F70-F93 HydrophobicContact CZ-CD1 4.02Å; F70-F93 AromaticContact CZ-CE1 3.77Å; F70-F93 HydrophobicContact CZ-CE1 3.77Å; F70-P180 HydrophobicContact CE1-CG 4.04Å; F70-P180 HydrophobicContact CZ-CB 4.41Å; F70-P180 HydrophobicContact CZ-CG 3.79Å
71L98.1Very high97.9Very high72 Ų7233.4 Ų33.438%0.37717%0.174SC..  trans-69128.5168.8-172.868000110.1T55 L57 D73T55-L71 PolarHBondContact O-N 3.35Å; L57-L71 HydrophobicContact CD1-CB 4.26Å; L57-L71 HydrophobicContact CD2-CB 4.32Å; L57-L71 HydrophobicContact CG-CB 4.46Å; L71-D73 HydrophobicContact CD1-CB 4.44Å; L71-D73 WeakPolarHBondContact CD2-OD1 3.32Å; L71-D73 WeakPolarHBondContact CG-OD1 3.28Å
72D97.8Very high97.8Very high26 Ų2633.9 Ų33.914%0.13918%0.179CC..  trans-129.423.1-171.864.4-38.7000113.5R89 K91 W123D72-R89 HydrophobicContact CB-CB 4.31Å; D72-R89 WeakPolarHBondContact O-CD 3.41Å; D72-R89 PolarHBondContact O-NH1 3.26Å; D72-K91 HydrophobicContact CB-CD 4.43Å; D72-K91 IonicContact OD1-NZ 3.2Å; D72-K91 PolarHBondContact OD1-NZ 2.96Å; D72-K91 VanDerWaalsContact OD2-CD 3.26Å; D72-K91 WeakPolarHBondContact OD2-CD 3.23Å; D72-K91 IonicContact OD2-NZ 3.79Å; D72-K91 PolarHBondContact OD2-NZ 2.62Å; D72-K91 VanDerWaalsContact OD2-NZ 3.11Å; D72-W123 PolarHBondContact OD2-NE1 2.91Å
73D96.2Very high97.8Very high96 Ų9632.7 Ų32.751%0.51317%0.174SC..SBendtrans-73.6-28.6179.964.2-16.5000113.2L71 R89L71-D73 HydrophobicContact CD1-CB 4.44Å; L71-D73 WeakPolarHBondContact CD2-OD1 3.32Å; L71-D73 WeakPolarHBondContact CG-OD1 3.28Å; D73-R89 PolarHBondContact O-NH1 2.73Å
74I95.4Very high97.8Very high96 Ų9633.1 Ų33.149%0.49218%0.176SC..SBendtrans-134173.1175.765.9171.5000112.3S76 R89I74-S76 WeakPolarHBondContact CD1-OG 3.31Å; I74-S76 WeakPolarHBondContact CG1-OG 3.49Å; I74-S76 PolarHBondContact O-N 2.71Å; I74-R89 PolarHBondContact O-NE 2.79Å
75D96.9Very high97.6Very high73 Ų7338.6 Ų38.639%0.3921%0.205SC..THydrogen-bonded Turntrans-78.748.7-177.6-68.73.8000113.1T78 N87 R89D75-T78 HydrophobicContact CB-CG2 3.96Å; D75-N87 PolarHBondContact OD2-ND2 3.25Å; D75-R89 IonicContact OD1-CZ 3.18Å; D75-R89 IonicContact OD1-NE 3.66Å; D75-R89 PolarHBondContact OD1-NE 3.2Å; D75-R89 IonicContact OD1-NH2 2.79Å; D75-R89 PolarHBondContact OD1-NH2 2.77Å
76S97.1Very high97.5Very high23 Ų2342.9 Ų42.916%0.16122%0.224CC..THydrogen-bonded Turntrans-81.1-46.3179.4-69.30000112.7I74I74-S76 WeakPolarHBondContact CD1-OG 3.31Å; I74-S76 WeakPolarHBondContact CG1-OG 3.49Å; I74-S76 PolarHBondContact O-N 2.71Å
77S98.3Very high97.4Very high2 Ų243.8 Ų43.81%0.01423%0.228CC..SBendtrans-118.7109.8-179.6-710000109.7K50 D52 T55 R89 L90K50-S77 CarbonylContact O-C 3.53Å; K50-S77 VanDerWaalsContact O-CA 3.29Å; K50-S77 WeakPolarHBondContact O-CA 3.39Å; D52-S77 PolarHBondContact N-OG 3.34Å; D52-S77 PolarHBondContact O-OG 3.38Å; T55-S77 PolarHBondContact OG1-OG 2.87Å; S77-R89 WeakPolarHBondContact O-CA 3.34Å; S77-L90 PolarHBondContact O-N 3.41Å
78T98.4Very high97.4Very high4 Ų441.8 Ų41.83%0.02522%0.219CC..EExtended strand (participates in β ladder)trans-142.1153.1-16360.10000114.9K50 D75 N87 H88 R89K50-T78 PolarHBondContact N-O 2.99Å; K50-T78 PolarHBondContact O-N 3.34Å; D75-T78 HydrophobicContact CB-CG2 3.96Å; T78-N87 VanDerWaalsContact CB-OD1 3.28Å; T78-N87 WeakPolarHBondContact CB-OD1 3.13Å; T78-N87 WeakPolarHBondContact CG2-ND2 3.49Å; T78-H88 CarbonylContact C-O 3.49Å; T78-H88 WeakPolarHBondContact CA-O 3.43Å; T78-R89 HydrophobicContact CG2-CG 4.44Å
79L98.6Very high97.4Very high0 Ų043.9 Ų43.90%023%0.227CC..EExtended strand (participates in β ladder)trans-115.4130.8165.9163.365.4000109.3L47 L49 V84 N87 H88 A141 V143 I209L47-L79 HydrophobicContact CD2-CD1 4Å; L49-L79 HydrophobicContact CD2-CB 3.79Å; L49-L79 HydrophobicContact CD2-CD1 3.49Å; L49-L79 VanDerWaalsContact CD2-CD1 3.49Å; L49-L79 HydrophobicContact CD2-CG 4.16Å; L49-L79 HydrophobicContact CG-CD1 4.29Å; L79-V84 HydrophobicContact CG-CG2 4.28Å; L79-N87 PolarHBondContact O-OD1 3.42Å; L79-H88 HydrophobicContact CB-CB 4.32Å; L79-H88 PolarHBondContact N-O 3.15Å; L79-H88 PolarHBondContact O-N 3.22Å; L79-A141 HydrophobicContact CD2-CB 3.7Å; L79-V143 HydrophobicContact CD2-CG2 4.2Å; L79-I209 HydrophobicContact CD1-CD1 4.46Å; L79-I209 HydrophobicContact CD2-CD1 3.73Å
80K97.9Very high97.4Very high88 Ų8843 Ų4338%0.38322%0.222SC..EExtended strand (participates in β ladder)trans-136164.8175.5-64.3179-178.1177.30111V48 N87V48-K80 HydrophobicContact CB-CB 4.12Å; V48-K80 HydrophobicContact CG1-CB 4.46Å; V48-K80 PolarHBondContact N-O 3.04Å; V48-K80 PolarHBondContact O-N 3.24Å; K80-N87 WeakPolarHBondContact CE-ND2 3.47Å; K80-N87 WeakPolarHBondContact CE-OD1 3.19Å; K80-N87 HydrophobicContact CG-CB 4.43Å; K80-N87 WeakPolarHBondContact CG-OD1 3.48Å
81D97.4Very high97.5Very high60 Ų6045.6 Ų45.632%0.32123%0.233SC..EExtended strand (participates in β ladder)trans55.7-149.5-179.3-72.1-51000112.4K45 P46 V48 V84K45-D81 HydrophobicContact CB-CB 4.12Å; K45-D81 HydrophobicContact CD-CB 4.02Å; K45-D81 WeakPolarHBondContact CD-OD1 3.5Å; K45-D81 IonicContact NZ-OD1 2.83Å; K45-D81 PolarHBondContact NZ-OD1 3.25Å; P46-D81 WeakPolarHBondContact O-CB 3.4Å; V48-D81 HydrophobicContact CG2-CB 4.13Å; D81-V84 WeakPolarHBondContact O-CG2 3.49Å; D81-V84 PolarHBondContact O-N 2.88Å
82G97.3Very high97.5Very high10 Ų1043.1 Ų43.110%0.10322%0.22CC..THydrogen-bonded Turntrans59.5-129.3-166.100000113.3K45 P46 Y190K45-G82 WeakPolarHBondContact O-CA 3.39Å; P46-G82 PolarHBondContact O-N 2.77Å; G82-Y190 WeakPolarHBondContact CA-OH 3.23Å
83P97.8Very high97.5Very high20 Ų2041.9 Ų41.913%0.1321%0.213CC..THydrogen-bonded Turntrans-86.4-6.3175.634.4-32.7000113.8L44 Y190 T192 T207 I209L44-P83 HydrophobicContact CD2-CB 3.9Å; P83-Y190 HydrophobicContact CG-CE2 4.22Å; P83-T192 HydrophobicContact CB-CG2 3.98Å; P83-T192 WeakPolarHBondContact CB-OG1 3.39Å; P83-T192 HydrophobicContact CG-CG2 4.34Å; P83-T192 WeakPolarHBondContact CG-OG1 3.37Å; P83-T207 HydrophobicContact CB-CG2 4.18Å; P83-T207 HydrophobicContact CG-CG2 3.99Å; P83-I209 HydrophobicContact CG-CD1 3.84Å; P83-I209 HydrophobicContact CG-CG1 3.53Å
84V97.5Very high97.7Very high13 Ų1338.3 Ų38.38%0.07919%0.193CC..  trans-91.6143.8-176.1-60.10000112L79 D81 A141 T207L79-V84 HydrophobicContact CG-CG2 4.28Å; D81-V84 WeakPolarHBondContact O-CG2 3.49Å; D81-V84 PolarHBondContact O-N 2.88Å; V84-A141 HydrophobicContact CG1-CB 3.74Å; V84-T207 HydrophobicContact CG1-CG2 4.39Å
85L93.7Very high97.8Very high160 Ų16033.7 Ų33.784%0.83817%0.17SC*.SBendtrans-90.7-33.4-178.3-65178000113.5
86F95.6Very high97.9Very high95 Ų9530.3 Ų30.342%0.41715%0.151SC..SBendtrans-115.2166-174.7-64.1-81.9000110.5H88 N124 K126F86-H88 PolarHBondContact O-CE1 3.4Å; F86-H88 PolarHBondContact O-ND1 2.82Å; F86-N124 WeakPolarHBondContact CB-OD1 3.46Å; F86-K126 HydrophobicContact CD1-CB 4.49Å; F86-K126 HydrophobicContact CD2-CB 4.47Å; F86-K126 HydrophobicContact CD2-CD 4.12Å; F86-K126 HydrophobicContact CE2-CD 3.83Å; F86-K126 HydrophobicContact CG-CB 4.31Å; F86-K126 HydrophobicContact CZ-CD 4.14Å
87N97.5Very high98Very high19 Ų1929.2 Ų29.210%0.10214%0.144CC..  trans-64138.6172.1-166.123.3000110.1D75 T78 L79 K80 T125D75-N87 PolarHBondContact OD2-ND2 3.25Å; T78-N87 VanDerWaalsContact CB-OD1 3.28Å; T78-N87 WeakPolarHBondContact CB-OD1 3.13Å; T78-N87 WeakPolarHBondContact CG2-ND2 3.49Å; L79-N87 PolarHBondContact O-OD1 3.42Å; K80-N87 WeakPolarHBondContact CE-ND2 3.47Å; K80-N87 WeakPolarHBondContact CE-OD1 3.19Å; K80-N87 HydrophobicContact CG-CB 4.43Å; K80-N87 WeakPolarHBondContact CG-OD1 3.48Å; N87-T125 HydrophobicContact CB-CG2 4.39Å; N87-T125 WeakPolarHBondContact O-CG2 3.38Å; N87-T125 PolarHBondContact O-N 2.88Å; N87-T125 PolarHBondContact O-OG1 2.97Å; N87-T125 VanDerWaalsContact O-OG1 3.11Å
88H98.7Very high98Very high3 Ų329.1 Ų29.11%0.01414%0.143CC..EExtended strand (participates in β ladder)trans-121132.1173.5-69.762000109.9T78 L79 F86 H122 W123 N124T78-H88 CarbonylContact C-O 3.49Å; T78-H88 WeakPolarHBondContact CA-O 3.43Å; L79-H88 HydrophobicContact CB-CB 4.32Å; L79-H88 PolarHBondContact N-O 3.15Å; L79-H88 PolarHBondContact O-N 3.22Å; F86-H88 PolarHBondContact O-CE1 3.4Å; F86-H88 PolarHBondContact O-ND1 2.82Å; H88-H122 HydrophobicContact CB-CB 3.64Å; H88-W123 CarbonylContact C-O 3.45Å; H88-W123 WeakPolarHBondContact CA-O 3.32Å; H88-N124 PolarHBondContact CD2-N 3.22Å; H88-N124 VanDerWaalsContact CD2-N 3.34Å; H88-N124 VanDerWaalsContact NE2-CB 3.33Å; H88-N124 WeakPolarHBondContact NE2-CB 3.43Å
89R98.8Very high98.1Very high44 Ų4431.6 Ų31.617%0.16616%0.16CC..EExtended strand (participates in β ladder)trans-91.5134.9176.8-72.2173.7-169178.7-2.5110.7D72 D73 I74 D75 S77 T78 K91 H122 W123 T125D72-R89 HydrophobicContact CB-CB 4.31Å; D72-R89 WeakPolarHBondContact O-CD 3.41Å; D72-R89 PolarHBondContact O-NH1 3.26Å; D73-R89 PolarHBondContact O-NH1 2.73Å; I74-R89 PolarHBondContact O-NE 2.79Å; D75-R89 IonicContact OD1-CZ 3.18Å; D75-R89 IonicContact OD1-NE 3.66Å; D75-R89 PolarHBondContact OD1-NE 3.2Å; D75-R89 IonicContact OD1-NH2 2.79Å; D75-R89 PolarHBondContact OD1-NH2 2.77Å; S77-R89 WeakPolarHBondContact O-CA 3.34Å; T78-R89 HydrophobicContact CG2-CG 4.44Å; R89-K91 PolarHBondContact O-N 2.7Å; R89-H122 CarbonylContact O-C 3.48Å; R89-H122 WeakPolarHBondContact O-CA 3.37Å; R89-H122 WeakPolarHBondContact O-CB 3.36Å; R89-W123 HydrophobicContact CB-CZ2 4.39Å; R89-W123 PolarHBondContact N-O 3.32Å; R89-W123 VanDerWaalsContact O-CD1 3.31Å; R89-W123 PolarHBondContact O-N 3.07Å; R89-T125 HydrophobicContact CB-CG2 4.45Å; R89-T125 HydrophobicContact CG-CG2 3.6Å
90L98.9Very high98Very high0 Ų033.7 Ų33.70%018%0.175CC..EExtended strand (participates in β ladder)trans-64.1126.5171.8178.467.4000109.1Y51 F70 S77 L120 P180Y51-L90 HydrophobicContact CD1-CB 4.4Å; Y51-L90 HydrophobicContact CD1-CD2 3.94Å; Y51-L90 HydrophobicContact CE1-CB 4.07Å; Y51-L90 HydrophobicContact CE1-CD2 3.94Å; Y51-L90 HydrophobicContact CE1-CG 4.42Å; F70-L90 HydrophobicContact CB-CD2 4.38Å; F70-L90 HydrophobicContact CB-CG 4.42Å; F70-L90 HydrophobicContact CD1-CD2 3.89Å; F70-L90 HydrophobicContact CD2-CD2 3.67Å; F70-L90 HydrophobicContact CD2-CG 4.02Å; F70-L90 HydrophobicContact CE1-CD2 4.05Å; F70-L90 HydrophobicContact CE2-CD2 3.87Å; F70-L90 HydrophobicContact CG-CD2 3.7Å; F70-L90 HydrophobicContact CG-CG 4.16Å; F70-L90 HydrophobicContact CZ-CD2 4.05Å; S77-L90 PolarHBondContact O-N 3.41Å; L90-L120 HydrophobicContact CD1-CB 4.33Å; L90-L120 HydrophobicContact CD1-CD2 4.14Å; L90-P180 HydrophobicContact CD2-CG 3.62Å
91K98.7Very high98.1Very high53 Ų5331.9 Ų31.923%0.2317%0.17CC..EExtended strand (participates in β ladder)trans-98.5-48.7174.2-177.856.7173178.30112F70 D72 R89 V121 F130F70-K91 PolarHBondContact N-O 3.08Å; D72-K91 HydrophobicContact CB-CD 4.43Å; D72-K91 IonicContact OD1-NZ 3.2Å; D72-K91 PolarHBondContact OD1-NZ 2.96Å; D72-K91 VanDerWaalsContact OD2-CD 3.26Å; D72-K91 WeakPolarHBondContact OD2-CD 3.23Å; D72-K91 IonicContact OD2-NZ 3.79Å; D72-K91 PolarHBondContact OD2-NZ 2.62Å; D72-K91 VanDerWaalsContact OD2-NZ 3.11Å; R89-K91 PolarHBondContact O-N 2.7Å; K91-V121 PolarHBondContact N-O 2.87Å; K91-F130 HydrophobicContact CB-CD2 3.96Å; K91-F130 HydrophobicContact CB-CE2 4.13Å; K91-F130 HydrophobicContact CD-CD2 4.47Å; K91-F130 HydrophobicContact CG-CD2 3.82Å; K91-F130 HydrophobicContact CG-CE2 4.07Å; K91-F130 HydrophobicContact CG-CG 4.38Å
92Q98.8Very high98.1Very high21 Ų2134.4 Ų34.410%0.09818%0.183CC..EExtended strand (participates in β ladder)trans-161.9165.6-173.154.885.9-1800110.6Q67 V68 H94 V121Q67-Q92 HydrophobicContact CG-CB 3.69Å; Q67-Q92 HydrophobicContact CG-CG 4.06Å; V68-Q92 CarbonylContact O-C 3.49Å; V68-Q92 WeakPolarHBondContact O-CA 3.32Å; V68-Q92 WeakPolarHBondContact O-CB 3.14Å; Q92-H94 PolarHBondContact NE2-ND1 3.21Å; Q92-H94 PolarHBondContact OE1-ND1 3.36Å; Q92-V121 HydrophobicContact CG-CB 4.24Å; Q92-V121 PolarHBondContact O-N 3.42Å
93F98.9Very high98.2Very high0 Ų035.4 Ų35.40%019%0.185CC..EExtended strand (participates in β ladder)trans-129.5159.5154.669.6-103.1000112.1F66 Q67 V68 F70 F95 L118 H119 L120 L159 F178 P180 L183F66-F93 HydrophobicContact CE2-CE2 4.4Å; Q67-F93 WeakPolarHBondContact CA-O 3.44Å; V68-F93 HydrophobicContact CB-CD1 4.09Å; V68-F93 HydrophobicContact CB-CD2 4.28Å; V68-F93 HydrophobicContact CB-CE1 3.63Å; V68-F93 HydrophobicContact CB-CE2 3.81Å; V68-F93 HydrophobicContact CB-CG 4.39Å; V68-F93 HydrophobicContact CB-CZ 3.49Å; V68-F93 VanDerWaalsContact CB-CZ 3.49Å; V68-F93 HydrophobicContact CG1-CD1 4.48Å; V68-F93 HydrophobicContact CG1-CE1 3.79Å; V68-F93 HydrophobicContact CG1-CZ 3.93Å; V68-F93 HydrophobicContact CG2-CD2 4.38Å; V68-F93 HydrophobicContact CG2-CE1 4.08Å; V68-F93 HydrophobicContact CG2-CE2 3.55Å; V68-F93 HydrophobicContact CG2-CZ 3.39Å; V68-F93 PolarHBondContact N-O 2.99Å; V68-F93 PolarHBondContact O-N 2.96Å; F70-F93 AromaticContact CE2-CD1 3.56Å; F70-F93 HydrophobicContact CE2-CD1 3.56Å; F70-F93 AromaticContact CE2-CE1 3.69Å; F70-F93 HydrophobicContact CE2-CE1 3.69Å; F70-F93 HydrophobicContact CZ-CD1 4.02Å; F70-F93 AromaticContact CZ-CE1 3.77Å; F70-F93 HydrophobicContact CZ-CE1 3.77Å; F93-F95 HydrophobicContact CD2-CD2 4.36Å; F93-F95 AromaticContact CD2-CE2 3.81Å; F93-F95 HydrophobicContact CD2-CE2 3.81Å; F93-F95 AromaticContact CE2-CE2 3.77Å; F93-F95 HydrophobicContact CE2-CE2 3.77Å; F93-L118 HydrophobicContact CB-CD1 3.85Å; F93-L118 HydrophobicContact CD2-CD1 3.79Å; F93-L118 HydrophobicContact CG-CD1 4.04Å; F93-H119 WeakPolarHBondContact CA-O 3.06Å; F93-H119 VanDerWaalsContact CB-O 3.24Å; F93-H119 WeakPolarHBondContact CB-O 3.18Å; F93-L120 HydrophobicContact CB-CD2 3.73Å; F93-L120 HydrophobicContact CB-CG 4.2Å; F93-L120 HydrophobicContact CD1-CD2 4.03Å; F93-L120 HydrophobicContact CG-CD2 4.19Å; F93-L159 HydrophobicContact CE2-CD1 3.93Å; F93-L159 HydrophobicContact CE2-CD2 4.11Å; F93-L159 HydrophobicContact CZ-CD1 4.07Å; F93-L159 HydrophobicContact CZ-CD2 3.87Å; F93-F178 AromaticContact CE1-CD1 3.88Å; F93-F178 HydrophobicContact CE1-CD1 3.88Å; F93-F178 AromaticContact CE1-CE1 3.72Å; F93-F178 HydrophobicContact CE1-CE1 3.72Å; F93-F178 HydrophobicContact CZ-CD1 4.06Å; F93-F178 AromaticContact CZ-CE1 3.65Å; F93-F178 HydrophobicContact CZ-CE1 3.65Å; F93-F178 HydrophobicContact CZ-CZ 4.4Å; F93-P180 HydrophobicContact CD1-CB 4.12Å; F93-P180 HydrophobicContact CE1-CB 4.17Å; F93-L183 HydrophobicContact CE2-CD1 4.24Å; F93-L183 HydrophobicContact CZ-CD1 4.12Å
94H98.9Very high98.3Very high20 Ų2034.4 Ų34.49%0.09318%0.179CC..EExtended strand (participates in β ladder)trans-152.3176.1175.659.8-73.9000109.9F66 Q92 H96 H119F66-H94 WeakPolarHBondContact O-CB 3.39Å; Q92-H94 PolarHBondContact NE2-ND1 3.21Å; Q92-H94 PolarHBondContact OE1-ND1 3.36Å; H94-H96 AromaticContact CD2-NE2 3.59Å; H94-H96 AromaticContact NE2-NE2 3.48Å; H94-H96 PolarHBondContact NE2-NE2 3.08Å; H94-H119 PolarHBondContact N-O 2.8Å; H94-H119 VanDerWaalsContact N-O 3.13Å; H94-H119 AromaticContact NE2-ND1 3.67Å; H94-H119 PolarHBondContact O-N 3.47Å
95F98.9Very high98.3Very high0 Ų033.9 Ų33.90%018%0.176CC..EExtended strand (participates in β ladder)trans-129.6153.7-179-67.8-108.3000111.2S65 F66 F93 W97 E117 L118 L147 L156 L159 L183 F225 N243S65-F95 PolarHBondContact OG-N 2.82Å; S65-F95 PolarHBondContact OG-O 3.37Å; F66-F95 HydrophobicContact CE1-CB 4.39Å; F66-F95 AromaticContact CE1-CD2 3.99Å; F66-F95 HydrophobicContact CE1-CD2 3.99Å; F66-F95 HydrophobicContact CE1-CG 4.46Å; F66-F95 AromaticContact CE2-CD2 3.68Å; F66-F95 HydrophobicContact CE2-CD2 3.68Å; F66-F95 AromaticContact CE2-CE2 3.86Å; F66-F95 HydrophobicContact CE2-CE2 3.86Å; F66-F95 HydrophobicContact CZ-CB 4.42Å; F66-F95 AromaticContact CZ-CD2 3.21Å; F66-F95 HydrophobicContact CZ-CD2 3.21Å; F66-F95 AromaticContact CZ-CE2 3.57Å; F66-F95 HydrophobicContact CZ-CE2 3.57Å; F66-F95 HydrophobicContact CZ-CG 4.04Å; F93-F95 HydrophobicContact CD2-CD2 4.36Å; F93-F95 AromaticContact CD2-CE2 3.81Å; F93-F95 HydrophobicContact CD2-CE2 3.81Å; F93-F95 AromaticContact CE2-CE2 3.77Å; F93-F95 HydrophobicContact CE2-CE2 3.77Å; F95-W97 HydrophobicContact CB-CE3 3.81Å; F95-W97 HydrophobicContact CB-CZ3 3.93Å; F95-W97 VanDerWaalsContact O-CZ3 3.23Å; F95-W97 WeakPolarHBondContact O-CZ3 3.31Å; F95-E117 CarbonylContact C-O 3.58Å; F95-E117 VanDerWaalsContact CA-O 3.31Å; F95-E117 WeakPolarHBondContact CA-O 3.43Å; F95-L118 HydrophobicContact CD1-CB 3.83Å; F95-L118 HydrophobicContact CD1-CD1 4.45Å; F95-L118 HydrophobicContact CD2-CD1 4.17Å; F95-L118 HydrophobicContact CE1-CB 3.6Å; F95-L118 HydrophobicContact CE1-CD1 4.07Å; F95-L118 HydrophobicContact CE1-CG 4.27Å; F95-L118 HydrophobicContact CE2-CD1 3.74Å; F95-L118 HydrophobicContact CZ-CB 4.12Å; F95-L118 HydrophobicContact CZ-CD1 3.7Å; F95-L118 HydrophobicContact CZ-CD2 4.39Å; F95-L118 HydrophobicContact CZ-CG 4.29Å; F95-L147 HydrophobicContact CD1-CD1 3.93Å; F95-L147 HydrophobicContact CD1-CD2 4.28Å; F95-L147 HydrophobicContact CE1-CD1 3.87Å; F95-L147 HydrophobicContact CE1-CD2 3.96Å; F95-L156 HydrophobicContact CE1-CD2 4.19Å; F95-L156 HydrophobicContact CZ-CD2 3.83Å; F95-L159 HydrophobicContact CE2-CD1 4.17Å; F95-L159 HydrophobicContact CZ-CD1 4.35Å; F95-L183 HydrophobicContact CZ-CD1 4.21Å; F95-F225 HydrophobicContact CB-CE1 4.05Å; F95-F225 AromaticContact CD1-CE1 3.84Å; F95-F225 HydrophobicContact CD1-CE1 3.84Å; F95-F225 HydrophobicContact CD1-CZ 4.43Å; F95-F225 HydrophobicContact CD2-CE1 4.16Å; F95-F225 HydrophobicContact CE1-CE1 4.24Å; F95-F225 HydrophobicContact CE1-CZ 4.38Å; F95-F225 AromaticContact CG-CE1 3.78Å; F95-F225 HydrophobicContact CG-CE1 3.78Å; F95-N243 PolarHBondContact O-ND2 3.04Å
96H98.9Very high98.6Very high2 Ų226.3 Ų26.31%0.00914%0.136CC..EExtended strand (participates in β ladder)trans-114.7140.1163.7-64.9-89.1000108.5H94 G104 E106 A116 E117 H119 N243H94-H96 AromaticContact CD2-NE2 3.59Å; H94-H96 AromaticContact NE2-NE2 3.48Å; H94-H96 PolarHBondContact NE2-NE2 3.08Å; H96-G104 CarbonylContact C-O 3.07Å; H96-E106 HydrophobicContact CB-CG 3.98Å; H96-E106 IonicContact CD2-OE2 3.54Å; H96-E106 IonicContact CE1-OE1 3.66Å; H96-E106 IonicContact CE1-OE2 3.7Å; H96-E106 IonicContact CG-OE2 3.93Å; H96-E106 IonicContact ND1-OE1 3.51Å; H96-E106 IonicContact ND1-OE2 3.59Å; H96-E106 IonicContact NE2-OE2 2.71Å; H96-E106 PolarHBondContact NE2-OE2 3.36Å; H96-A116 CarbonylContact O-C 3.56Å; H96-A116 WeakPolarHBondContact O-CA 3.33Å; H96-A116 WeakPolarHBondContact O-CB 3.45Å; H96-E117 PolarHBondContact N-O 2.77Å; H96-E117 PolarHBondContact O-N 2.87Å; H96-H119 AromaticContact CD2-CE1 3.38Å; H96-H119 PolarHBondContact CD2-CE1 2.97Å; H96-H119 AromaticContact CD2-ND1 3.53Å; H96-H119 AromaticContact NE2-CE1 3.64Å; H96-H119 AromaticContact NE2-ND1 3.55Å; H96-N243 WeakPolarHBondContact CA-OD1 3.11Å; H96-N243 PolarHBondContact ND1-O 2.92Å
97W98.9Very high98.7Very high0 Ų021.8 Ų21.80%012%0.116CC..EExtended strand (participates in β ladder)trans-150.7159-178.962.290.3000112.7F66 F95 P115 A116 M222 F225 L228 M240 D242 N243F66-W97 AromaticContact CD1-CH2 3.85Å; F66-W97 HydrophobicContact CD1-CH2 3.85Å; F66-W97 AromaticContact CD1-CZ3 3.99Å; F66-W97 HydrophobicContact CD1-CZ3 3.99Å; F66-W97 HydrophobicContact CE1-CH2 4.22Å; F66-W97 AromaticContact CE1-CZ3 3.98Å; F66-W97 HydrophobicContact CE1-CZ3 3.98Å; F95-W97 HydrophobicContact CB-CE3 3.81Å; F95-W97 HydrophobicContact CB-CZ3 3.93Å; F95-W97 VanDerWaalsContact O-CZ3 3.23Å; F95-W97 WeakPolarHBondContact O-CZ3 3.31Å; W97-P115 WeakPolarHBondContact CA-O 3.33Å; W97-A116 HydrophobicContact CB-CB 3.88Å; W97-M222 HydrophobicContact CB-CE 3.79Å; W97-F225 HydrophobicContact CD2-CB 4.22Å; W97-F225 HydrophobicContact CD2-CD1 4.11Å; W97-F225 AromaticContact CE3-CD1 3.91Å; W97-F225 HydrophobicContact CE3-CD1 3.91Å; W97-F225 HydrophobicContact CG-CB 4.28Å; W97-F225 HydrophobicContact CZ3-CD1 4.3Å; W97-L228 HydrophobicContact CH2-CD1 4.12Å; W97-L228 HydrophobicContact CZ2-CD1 4.21Å; W97-M240 HydrophobicContact CH2-CG 4.03Å; W97-M240 HydrophobicContact CH2-SD 3.39Å; W97-M240 WeakPolarHBondContact CH2-SD 3.38Å; W97-M240 HydrophobicContact CZ2-CB 3.99Å; W97-M240 HydrophobicContact CZ2-CG 3.41Å; W97-M240 VanDerWaalsContact CZ2-CG 3.41Å; W97-M240 HydrophobicContact CZ2-SD 3.38Å; W97-M240 WeakPolarHBondContact CZ2-SD 3.38Å; W97-M240 PolarHBondContact NE1-O 3.11Å; W97-D242 WeakPolarHBondContact O-CA 3.34Å; W97-D242 PolarHBondContact O-N 2.8Å; W97-D242 VanDerWaalsContact O-N 3.15Å; W97-N243 WeakPolarHBondContact CZ3-ND2 3.49Å; W97-N243 PolarHBondContact N-OD1 3.46Å; W97-N243 PolarHBondContact O-N 3.09Å; W97-N243 PolarHBondContact O-OD1 3.46Å; W97-N243 VanDerWaalsContact O-OD1 3.07Å
98G98.8Very high98.8Very high0 Ų021.1 Ų21.10%011%0.113CC..  trans-100.3171.4-178.700000112.9S100 H103 P115 R226 D242G98-S100 PolarHBondContact O-N 3.07Å; G98-H103 VanDerWaalsContact CA-O 3.29Å; G98-H103 WeakPolarHBondContact CA-O 3.47Å; G98-H103 PolarHBondContact N-O 3.11Å; G98-P115 PolarHBondContact N-O 2.97Å; G98-R226 PolarHBondContact O-NE 3.39Å; G98-D242 WeakPolarHBondContact CA-OD1 3.43Å
99S98.6Very high98.8Very high55 Ų5521.9 Ų21.939%0.38512%0.118SC..SBendtrans-70.4-18.3174.551.20000113.6H103 R226 D242S99-H103 PolarHBondContact OG-NE2 2.95Å; S99-R226 WeakPolarHBondContact O-CD 3.48Å; S99-R226 PolarHBondContact O-NE 3Å; S99-D242 WeakPolarHBondContact CB-OD2 3.14Å; S99-D242 PolarHBondContact N-OD1 3.19Å; S99-D242 PolarHBondContact OG-OD1 3.05Å; S99-D242 PolarHBondContact OG-OD2 3.19Å
100S98.5Very high98.8Very high45 Ų4523 Ų2332%0.31514%0.136SC..SBendtrans-140.6172.8174.552.40000112.8G98 D102 H103 R226G98-S100 PolarHBondContact O-N 3.07Å; S100-D102 VanDerWaalsContact C-N 3.26Å; S100-D102 WeakPolarHBondContact CB-OD1 3.43Å; S100-D102 PolarHBondContact O-N 2.79Å; S100-D102 PolarHBondContact OG-OD1 2.98Å; S100-H103 PolarHBondContact OG-CE1 2.95Å; S100-H103 PolarHBondContact OG-ND1 2.81Å; S100-R226 PolarHBondContact O-NH2 3.12Å
101D98.8Very high98.8Very high49 Ų4925.4 Ų25.426%0.26216%0.161SC..THydrogen-bonded Turntrans-74.8-11.5-170.5-78.92.7000114.5P115 I149 S219 R226D101-P115 WeakPolarHBondContact O-CB 3.42Å; D101-I149 HydrophobicContact CB-CD1 3.92Å; D101-I149 HydrophobicContact CB-CG1 3.7Å; D101-I149 VanDerWaalsContact CG-CD1 3.46Å; D101-S219 WeakPolarHBondContact OD2-CB 3.42Å; D101-S219 PolarHBondContact OD2-OG 2.94Å; D101-R226 IonicContact OD1-CZ 3.64Å; D101-R226 IonicContact OD1-NH1 3.42Å; D101-R226 PolarHBondContact OD1-NH1 3.01Å; D101-R226 IonicContact OD1-NH2 3.19Å; D101-R226 PolarHBondContact OD1-NH2 2.89Å
102D98.3Very high98.8Very high114 Ų11426.7 Ų26.761%0.6117%0.173SC*.THydrogen-bonded Turntrans-90.3-5.4-177.964.1-21.3000113.7S100S100-D102 VanDerWaalsContact C-N 3.26Å; S100-D102 WeakPolarHBondContact CB-OD1 3.43Å; S100-D102 PolarHBondContact O-N 2.79Å; S100-D102 PolarHBondContact OG-OD1 2.98Å
103H98.8Very high98.7Very high30 Ų3029.7 Ų29.714%0.13919%0.186CC..  trans-158.7164.9179.265.5-89.2000113G98 S99 S100 K113 Y114 P115 D242 Y244G98-H103 VanDerWaalsContact CA-O 3.29Å; G98-H103 WeakPolarHBondContact CA-O 3.47Å; G98-H103 PolarHBondContact N-O 3.11Å; S99-H103 PolarHBondContact OG-NE2 2.95Å; S100-H103 PolarHBondContact OG-CE1 2.95Å; S100-H103 PolarHBondContact OG-ND1 2.81Å; H103-K113 HydrophobicContact CB-CB 4.26Å; H103-K113 HydrophobicContact CB-CD 3.7Å; H103-Y114 CarbonylContact C-O 3.52Å; H103-Y114 WeakPolarHBondContact CA-O 3.16Å; H103-P115 WeakPolarHBondContact O-CA 3.49Å; H103-D242 IonicContact CD2-OD1 3.11Å; H103-D242 IonicContact NE2-OD1 3.72Å; H103-D242 PolarHBondContact NE2-OD1 3.02Å; H103-D242 VanDerWaalsContact NE2-OD1 3.11Å; H103-Y244 AromaticContact CD2-CE1 3.74Å; H103-Y244 AromaticContact CD2-CZ 3.84Å; H103-Y244 PolarHBondContact CD2-OH 2.78Å; H103-Y244 VanDerWaalsContact CD2-OH 3.24Å
104G98.8Very high98.7Very high0 Ų031.9 Ų31.90%020%0.195CC..  trans145.6-22.6178.300000115.4H96 Y114 P115 Y244H96-G104 CarbonylContact C-O 3.07Å; G104-Y114 CarbonylContact C-O 3.42Å; G104-Y114 WeakPolarHBondContact CA-O 3.33Å; G104-Y114 PolarHBondContact N-O 2.78Å; G104-P115 WeakPolarHBondContact CA-O 3.26Å; G104-Y244 WeakPolarHBondContact O-CB 3.33Å
105S98.9Very high98.7Very high2 Ų231.2 Ų31.21%0.01419%0.192CC..  trans-66.5149.3169.3680000111.4H107 Y114S105-H107 WeakPolarHBondContact CB-O 3.13Å; S105-H107 PolarHBondContact OG-O 2.89Å; S105-Y114 PolarHBondContact N-O 3.41Å; S105-Y114 PolarHBondContact OG-N 3.33Å
106E98.9Very high98.7Very high0 Ų031.2 Ų31.20%019%0.192CC..SBendtrans-84.7-52.5177.9-83.9-158.2132.400110.2P30 H96 E117 H119 T198 R245P30-E106 HydrophobicContact CB-CB 3.79Å; P30-E106 WeakPolarHBondContact CB-O 3.38Å; P30-E106 VanDerWaalsContact CG-C 3.48Å; P30-E106 HydrophobicContact CG-CB 3.69Å; P30-E106 HydrophobicContact CG-CG 4.39Å; P30-E106 WeakPolarHBondContact CG-O 3.45Å; H96-E106 HydrophobicContact CB-CG 3.98Å; H96-E106 IonicContact CD2-OE2 3.54Å; H96-E106 IonicContact CE1-OE1 3.66Å; H96-E106 IonicContact CE1-OE2 3.7Å; H96-E106 IonicContact CG-OE2 3.93Å; H96-E106 IonicContact ND1-OE1 3.51Å; H96-E106 IonicContact ND1-OE2 3.59Å; H96-E106 IonicContact NE2-OE2 2.71Å; H96-E106 PolarHBondContact NE2-OE2 3.36Å; E106-E117 PolarHBondContact N-OE2 3.3Å; E106-H119 IonicContact OE2-CE1 3.62Å; E106-H119 PolarHBondContact OE2-CE1 3.38Å; E106-T198 VanDerWaalsContact CD-CB 3.49Å; E106-T198 WeakPolarHBondContact OE1-CB 3.2Å; E106-T198 PolarHBondContact OE1-OG1 2.99Å; E106-T198 WeakPolarHBondContact OE2-CB 3.28Å; E106-T198 WeakPolarHBondContact OE2-CG2 3.45Å; E106-T198 PolarHBondContact OE2-OG1 3.1Å; E106-R245 WeakPolarHBondContact OE1-CA 3.03Å; E106-R245 WeakPolarHBondContact OE1-CB 3.29Å; E106-R245 PolarHBondContact OE1-N 2.92Å
107H98.9Very high98.7Very high0 Ų031.1 Ų31.10%019%0.192CC..SBendtrans-70.6153.1168.3-65.989.1000110.4S105 E117 F146 Y193 W208S105-H107 WeakPolarHBondContact CB-O 3.13Å; S105-H107 PolarHBondContact OG-O 2.89Å; H107-E117 IonicContact CE1-OE1 2.8Å; H107-E117 IonicContact CG-OE1 3.82Å; H107-E117 PolarHBondContact N-OE2 2.77Å; H107-E117 IonicContact ND1-OE1 3.34Å; H107-E117 PolarHBondContact ND1-OE1 3.35Å; H107-E117 IonicContact ND1-OE2 3.83Å; H107-F146 HydrophobicContact CB-CE1 3.75Å; H107-F146 HydrophobicContact CB-CZ 3.6Å; H107-F146 WeakPolarHBondContact O-CE1 3.36Å; H107-Y193 AromaticContact NE2-CE1 3.48Å; H107-Y193 WeakPolarHBondContact NE2-CE1 3.41Å; H107-Y193 AromaticContact NE2-CZ 3.47Å; H107-Y193 PolarHBondContact NE2-OH 3.06Å; H107-W208 AromaticContact CE1-CD2 3.69Å; H107-W208 AromaticContact CE1-CE2 3.97Å; H107-W208 AromaticContact CE1-CE3 3.45Å; H107-W208 VanDerWaalsContact CE1-CE3 3.45Å; H107-W208 AromaticContact CE1-CH2 3.9Å; H107-W208 AromaticContact CE1-CZ3 3.55Å
108T98.9Very high98.7Very high6 Ų631.1 Ų31.14%0.03719%0.192CC..EExtended strand (participates in β ladder)trans-128.4151.8171.2620000109.9I31 N32 I33 T112 K113 P247I31-T108 PolarHBondContact O-N 3.23Å; N32-T108 WeakPolarHBondContact CA-OG1 3.15Å; N32-T108 VanDerWaalsContact CB-OG1 3.26Å; N32-T108 WeakPolarHBondContact CB-OG1 3.31Å; N32-T108 VanDerWaalsContact CG-OG1 3.3Å; N32-T108 PolarHBondContact OD1-O 2.86Å; N32-T108 PolarHBondContact OD1-OG1 3.36Å; I33-T108 PolarHBondContact N-O 2.8Å; T108-T112 CarbonylContact C-O 3.44Å; T108-T112 WeakPolarHBondContact CA-O 3.07Å; T108-T112 VanDerWaalsContact CB-O 3.26Å; T108-T112 WeakPolarHBondContact CB-O 3.32Å; T108-K113 HydrophobicContact CG2-CG 3.65Å; T108-P247 HydrophobicContact CG2-CG 4Å
109V98.8Very high98.7Very high19 Ų1931.3 Ų31.312%0.11519%0.192CC..EExtended strand (participates in β ladder)trans-114.8110175.5-175.80000108.9I33 P35 G111 T112 Y114 F146 W191I33-V109 CarbonylContact O-C 3.32Å; I33-V109 WeakPolarHBondContact O-CA 3.26Å; P35-V109 HydrophobicContact CG-CG1 3.62Å; V109-G111 PolarHBondContact O-N 2.75Å; V109-T112 PolarHBondContact N-O 2.99Å; V109-T112 WeakPolarHBondContact O-CB 3.21Å; V109-T112 PolarHBondContact O-N 3.43Å; V109-T112 PolarHBondContact O-OG1 2.72Å; V109-T112 VanDerWaalsContact O-OG1 3.11Å; V109-Y114 HydrophobicContact CG2-CE2 4.47Å; V109-F146 HydrophobicContact CG2-CE2 3.71Å; V109-F146 HydrophobicContact CG2-CZ 3.96Å; V109-W191 HydrophobicContact CG1-CH2 4Å; V109-W191 HydrophobicContact CG1-CZ2 4.46Å; V109-W191 HydrophobicContact CG2-CH2 4.17Å; V109-W191 HydrophobicContact CG2-CZ3 4.04Å
110A98.3Very high98.8Very high66 Ų6628.7 Ų28.755%0.54517%0.174SC..THydrogen-bonded Turntrans49.941-172.500000112.7N32 I33 T112N32-A110 PolarHBondContact OD1-N 2.96Å; I33-A110 PolarHBondContact O-N 2.93Å; A110-T112 PolarHBondContact O-N 3.16Å
111G98.4Very high98.8Very high51 Ų5126.7 Ų26.753%0.52616%0.16SC..THydrogen-bonded Turntrans81.1-8.7-176.500000115.1N32 V109N32-G111 PolarHBondContact OD1-N 2.86Å; V109-G111 PolarHBondContact O-N 2.75Å
112T98.6Very high98.8Very high80 Ų8024.4 Ų24.449%0.49115%0.148SC..BIsolated β-bridgetrans-72128.5175.9-51.70000110.2T108 V109 A110T108-T112 CarbonylContact C-O 3.44Å; T108-T112 WeakPolarHBondContact CA-O 3.07Å; T108-T112 VanDerWaalsContact CB-O 3.26Å; T108-T112 WeakPolarHBondContact CB-O 3.32Å; V109-T112 PolarHBondContact N-O 2.99Å; V109-T112 WeakPolarHBondContact O-CB 3.21Å; V109-T112 PolarHBondContact O-N 3.43Å; V109-T112 PolarHBondContact O-OG1 2.72Å; V109-T112 VanDerWaalsContact O-OG1 3.11Å; A110-T112 PolarHBondContact O-N 3.16Å
113K98.7Very high98.8Very high84 Ų8419.3 Ų19.337%0.36512%0.12SC..  trans-100159171.7-65.7-176.1177.4-173.20110.5H103 T108H103-K113 HydrophobicContact CB-CB 4.26Å; H103-K113 HydrophobicContact CB-CD 3.7Å; T108-K113 HydrophobicContact CG2-CG 3.65Å
114Y98.9Very high98.8Very high47 Ų4718 Ų1818%0.18411%0.114CC..  trans-118.4157.3173.9-71.5-89.8000109.6H103 G104 S105 V109 A116 F146 L147 K148 P214H103-Y114 CarbonylContact C-O 3.52Å; H103-Y114 WeakPolarHBondContact CA-O 3.16Å; G104-Y114 CarbonylContact C-O 3.42Å; G104-Y114 WeakPolarHBondContact CA-O 3.33Å; G104-Y114 PolarHBondContact N-O 2.78Å; S105-Y114 PolarHBondContact N-O 3.41Å; S105-Y114 PolarHBondContact OG-N 3.33Å; V109-Y114 HydrophobicContact CG2-CE2 4.47Å; Y114-A116 PolarHBondContact O-N 2.8Å; Y114-F146 HydrophobicContact CD1-CB 3.97Å; Y114-F146 HydrophobicContact CD2-CB 3.86Å; Y114-F146 AromaticContact CD2-CD1 3.44Å; Y114-F146 HydrophobicContact CD2-CD1 3.44Å; Y114-F146 VanDerWaalsContact CD2-CD1 3.44Å; Y114-F146 HydrophobicContact CD2-CD2 4.14Å; Y114-F146 AromaticContact CD2-CE1 3.95Å; Y114-F146 HydrophobicContact CD2-CE1 3.95Å; Y114-F146 AromaticContact CD2-CG 3.54Å; Y114-F146 HydrophobicContact CD2-CG 3.54Å; Y114-F146 HydrophobicContact CD2-CZ 4.48Å; Y114-F146 HydrophobicContact CE1-CB 4.28Å; Y114-F146 HydrophobicContact CE2-CB 4.18Å; Y114-F146 HydrophobicContact CE2-CD1 4.07Å; Y114-F146 AromaticContact CE2-CD2 3.92Å; Y114-F146 HydrophobicContact CE2-CD2 3.92Å; Y114-F146 HydrophobicContact CE2-CE1 4.43Å; Y114-F146 HydrophobicContact CE2-CE2 4.29Å; Y114-F146 AromaticContact CE2-CG 3.79Å; Y114-F146 HydrophobicContact CE2-CG 3.79Å; Y114-F146 HydrophobicContact CG-CB 3.76Å; Y114-F146 AromaticContact CG-CD1 3.94Å; Y114-F146 HydrophobicContact CG-CD1 3.94Å; Y114-F146 AromaticContact CG-CG 3.96Å; Y114-F146 HydrophobicContact CG-CG 3.96Å; Y114-L147 VanDerWaalsContact CB-O 3.32Å; Y114-L147 WeakPolarHBondContact CB-O 3.34Å; Y114-K148 HydrophobicContact CD1-CB 4.05Å; Y114-K148 HydrophobicContact CE1-CB 4.26Å; Y114-P214 HydrophobicContact CD1-CB 4.38Å; Y114-P214 HydrophobicContact CE1-CB 4Å; Y114-P214 HydrophobicContact CE1-CG 4.06Å
115P98.8Very high98.8Very high6 Ų620 Ų204%0.03913%0.127CC..SBendtrans-59-28.6178.620.1-34.9000114.5W97 G98 D101 H103 G104 L147 I149 M222W97-P115 WeakPolarHBondContact CA-O 3.33Å; G98-P115 PolarHBondContact N-O 2.97Å; D101-P115 WeakPolarHBondContact O-CB 3.42Å; H103-P115 WeakPolarHBondContact O-CA 3.49Å; G104-P115 WeakPolarHBondContact CA-O 3.26Å; P115-L147 WeakPolarHBondContact CD-O 3.42Å; P115-L147 WeakPolarHBondContact CG-O 3.35Å; P115-I149 HydrophobicContact CB-CD1 4.14Å; P115-I149 HydrophobicContact CG-CD1 3.93Å; P115-I149 HydrophobicContact CG-CG1 4.12Å; P115-M222 HydrophobicContact CB-CE 4.23Å; P115-M222 HydrophobicContact CB-CG 4.41Å; P115-M222 HydrophobicContact CB-SD 4.4Å
116A98.9Very high98.7Very high0 Ų025 Ų250%015%0.148CC..EExtended strand (participates in β ladder)trans-158166.3178.500000112.1H96 W97 Y114 L147 M222H96-A116 CarbonylContact O-C 3.56Å; H96-A116 WeakPolarHBondContact O-CA 3.33Å; H96-A116 WeakPolarHBondContact O-CB 3.45Å; W97-A116 HydrophobicContact CB-CB 3.88Å; Y114-A116 PolarHBondContact O-N 2.8Å; A116-L147 HydrophobicContact CB-CB 4.08Å; A116-L147 HydrophobicContact CB-CD1 4.03Å; A116-L147 HydrophobicContact CB-CD2 4.15Å; A116-L147 HydrophobicContact CB-CG 4.3Å; A116-L147 PolarHBondContact O-N 2.9Å; A116-M222 HydrophobicContact CB-CE 3.9Å; A116-M222 HydrophobicContact CB-SD 4.09Å
117E98.9Very high98.7Very high0 Ų026 Ų260%015%0.152CC..EExtended strand (participates in β ladder)trans-140.1125.8174.4-167.6178.4138.400110.2F95 H96 E106 H107 H119 V145 F146F95-E117 CarbonylContact C-O 3.58Å; F95-E117 VanDerWaalsContact CA-O 3.31Å; F95-E117 WeakPolarHBondContact CA-O 3.43Å; H96-E117 PolarHBondContact N-O 2.77Å; H96-E117 PolarHBondContact O-N 2.87Å; E106-E117 PolarHBondContact N-OE2 3.3Å; H107-E117 IonicContact CE1-OE1 2.8Å; H107-E117 IonicContact CG-OE1 3.82Å; H107-E117 PolarHBondContact N-OE2 2.77Å; H107-E117 IonicContact ND1-OE1 3.34Å; H107-E117 PolarHBondContact ND1-OE1 3.35Å; H107-E117 IonicContact ND1-OE2 3.83Å; E117-H119 IonicContact OE1-CD2 3.11Å; E117-H119 IonicContact OE1-CE1 2.76Å; E117-H119 IonicContact OE1-NE2 3.76Å; E117-H119 PolarHBondContact OE1-NE2 2.89Å; E117-V145 WeakPolarHBondContact CA-O 3.42Å; E117-F146 HydrophobicContact CG-CD1 4.14Å; E117-F146 HydrophobicContact CG-CE1 4.32Å; E117-F146 WeakPolarHBondContact OE2-CE1 3.41Å
118L98.9Very high98.6Very high0 Ų029.7 Ų29.70%018%0.182CC..EExtended strand (participates in β ladder)trans-85.2136172.9163.463.4000109.7F93 F95 L120 G144 V145 L147 L183F93-L118 HydrophobicContact CB-CD1 3.85Å; F93-L118 HydrophobicContact CD2-CD1 3.79Å; F93-L118 HydrophobicContact CG-CD1 4.04Å; F95-L118 HydrophobicContact CD1-CB 3.83Å; F95-L118 HydrophobicContact CD1-CD1 4.45Å; F95-L118 HydrophobicContact CD2-CD1 4.17Å; F95-L118 HydrophobicContact CE1-CB 3.6Å; F95-L118 HydrophobicContact CE1-CD1 4.07Å; F95-L118 HydrophobicContact CE1-CG 4.27Å; F95-L118 HydrophobicContact CE2-CD1 3.74Å; F95-L118 HydrophobicContact CZ-CB 4.12Å; F95-L118 HydrophobicContact CZ-CD1 3.7Å; F95-L118 HydrophobicContact CZ-CD2 4.39Å; F95-L118 HydrophobicContact CZ-CG 4.29Å; L118-L120 HydrophobicContact CD1-CG 4.39Å; L118-L120 HydrophobicContact CD2-CD1 4.31Å; L118-L120 HydrophobicContact CD2-CG 4.4Å; L118-L120 HydrophobicContact CG-CG 4.37Å; L118-G144 CarbonylContact O-C 3.6Å; L118-G144 VanDerWaalsContact O-CA 3.27Å; L118-G144 WeakPolarHBondContact O-CA 3.46Å; L118-V145 HydrophobicContact CB-CB 4.19Å; L118-V145 HydrophobicContact CD2-CB 4.26Å; L118-V145 HydrophobicContact CD2-CG2 4.39Å; L118-V145 PolarHBondContact N-O 3.45Å; L118-V145 PolarHBondContact O-N 3.04Å; L118-L147 HydrophobicContact CB-CD1 4.19Å; L118-L183 HydrophobicContact CD2-CB 3.63Å; L118-L183 HydrophobicContact CD2-CD1 4.16Å
119H98.9Very high98.6Very high3 Ų333.2 Ų33.21%0.01420%0.201CC..EExtended strand (participates in β ladder)trans-119115.4169.4-66.4169.1000111.5F93 H94 H96 E106 E117 V142 W208F93-H119 WeakPolarHBondContact CA-O 3.06Å; F93-H119 VanDerWaalsContact CB-O 3.24Å; F93-H119 WeakPolarHBondContact CB-O 3.18Å; H94-H119 PolarHBondContact N-O 2.8Å; H94-H119 VanDerWaalsContact N-O 3.13Å; H94-H119 AromaticContact NE2-ND1 3.67Å; H94-H119 PolarHBondContact O-N 3.47Å; H96-H119 AromaticContact CD2-CE1 3.38Å; H96-H119 PolarHBondContact CD2-CE1 2.97Å; H96-H119 AromaticContact CD2-ND1 3.53Å; H96-H119 AromaticContact NE2-CE1 3.64Å; H96-H119 AromaticContact NE2-ND1 3.55Å; E106-H119 IonicContact OE2-CE1 3.62Å; E106-H119 PolarHBondContact OE2-CE1 3.38Å; E117-H119 IonicContact OE1-CD2 3.11Å; E117-H119 IonicContact OE1-CE1 2.76Å; E117-H119 IonicContact OE1-NE2 3.76Å; E117-H119 PolarHBondContact OE1-NE2 2.89Å; H119-V142 HydrophobicContact CB-CG1 3.74Å; H119-W208 AromaticContact CD2-CH2 3.73Å; H119-W208 AromaticContact CD2-CZ3 3.65Å; H119-W208 AromaticContact CE1-CH2 3.37Å; H119-W208 WeakPolarHBondContact CE1-CH2 3.41Å; H119-W208 AromaticContact CG-CH2 3.88Å; H119-W208 AromaticContact ND1-CH2 3.64Å; H119-W208 AromaticContact NE2-CH2 3.41Å; H119-W208 WeakPolarHBondContact NE2-CH2 3.17Å; H119-W208 AromaticContact NE2-CZ3 3.56Å
120L98.9Very high98.5Very high0 Ų035.1 Ų35.10%021%0.207CC..EExtended strand (participates in β ladder)trans-92.9107.7168.7-67.9150.6000109L90 F93 L118 H122 V142 V143 P180 L184L90-L120 HydrophobicContact CD1-CB 4.33Å; L90-L120 HydrophobicContact CD1-CD2 4.14Å; F93-L120 HydrophobicContact CB-CD2 3.73Å; F93-L120 HydrophobicContact CB-CG 4.2Å; F93-L120 HydrophobicContact CD1-CD2 4.03Å; F93-L120 HydrophobicContact CG-CD2 4.19Å; L118-L120 HydrophobicContact CD1-CG 4.39Å; L118-L120 HydrophobicContact CD2-CD1 4.31Å; L118-L120 HydrophobicContact CD2-CG 4.4Å; L118-L120 HydrophobicContact CG-CG 4.37Å; L120-H122 PolarHBondContact O-CE1 3.01Å; L120-H122 PolarHBondContact O-ND1 2.86Å; L120-V142 WeakPolarHBondContact O-CA 3.22Å; L120-V143 HydrophobicContact CB-CB 4.18Å; L120-V143 HydrophobicContact CD1-CB 4.24Å; L120-V143 HydrophobicContact CD1-CG1 4.37Å; L120-V143 PolarHBondContact N-O 3.22Å; L120-V143 PolarHBondContact O-N 3.06Å; L120-P180 HydrophobicContact CD2-CB 3.55Å; L120-P180 HydrophobicContact CD2-CG 4.33Å; L120-L184 HydrophobicContact CD1-CD2 3.64Å
121V98.9Very high98.4Very high4 Ų434.2 Ų34.22%0.02421%0.205CC..EExtended strand (participates in β ladder)trans-94.8120.5-172.4-175.30000110.7K91 Q92 F130 V142K91-V121 PolarHBondContact N-O 2.87Å; Q92-V121 HydrophobicContact CG-CB 4.24Å; Q92-V121 PolarHBondContact O-N 3.42Å; V121-F130 HydrophobicContact CG1-CE2 4.05Å; V121-V142 HydrophobicContact CB-CG2 4.48Å; V121-V142 HydrophobicContact CG1-CG2 4.3Å; V121-V142 HydrophobicContact CG2-CG2 4.15Å
122H98.9Very high98.4Very high0 Ų035.7 Ų35.70%020%0.198CC..EExtended strand (participates in β ladder)trans-118.7154.7177-46.873.3000111Y51 H88 R89 L120 L140 A141Y51-H122 AromaticContact CE1-NE2 3.48Å; Y51-H122 WeakPolarHBondContact CE1-NE2 3.31Å; Y51-H122 AromaticContact CZ-NE2 3.57Å; Y51-H122 PolarHBondContact OH-CE1 3.07Å; Y51-H122 PolarHBondContact OH-NE2 3.17Å; H88-H122 HydrophobicContact CB-CB 3.64Å; R89-H122 CarbonylContact O-C 3.48Å; R89-H122 WeakPolarHBondContact O-CA 3.37Å; R89-H122 WeakPolarHBondContact O-CB 3.36Å; L120-H122 PolarHBondContact O-CE1 3.01Å; L120-H122 PolarHBondContact O-ND1 2.86Å; H122-L140 CarbonylContact O-C 3.49Å; H122-L140 VanDerWaalsContact O-CA 3.28Å; H122-L140 WeakPolarHBondContact O-CA 3.4Å; H122-A141 WeakPolarHBondContact CA-O 3.29Å; H122-A141 WeakPolarHBondContact CB-O 3.26Å; H122-A141 PolarHBondContact N-O 3.03Å; H122-A141 PolarHBondContact ND1-O 3.1Å; H122-A141 PolarHBondContact O-N 2.92Å
123W98.8Very high98.4Very high7 Ų731.9 Ų31.93%0.02718%0.175CC..EExtended strand (participates in β ladder)trans-126.4143.6176.867-86000112.3D72 H88 R89 T125 Y127 F130 A133 G139 L140D72-W123 PolarHBondContact OD2-NE1 2.91Å; H88-W123 CarbonylContact C-O 3.45Å; H88-W123 WeakPolarHBondContact CA-O 3.32Å; R89-W123 HydrophobicContact CB-CZ2 4.39Å; R89-W123 PolarHBondContact N-O 3.32Å; R89-W123 VanDerWaalsContact O-CD1 3.31Å; R89-W123 PolarHBondContact O-N 3.07Å; W123-T125 PolarHBondContact O-N 2.79Å; W123-Y127 WeakPolarHBondContact CZ3-O 3.47Å; W123-F130 HydrophobicContact CB-CD2 3.76Å; W123-F130 HydrophobicContact CB-CE2 4.45Å; W123-F130 AromaticContact CD1-CD2 3.82Å; W123-F130 HydrophobicContact CD2-CB 4.46Å; W123-F130 HydrophobicContact CG-CB 4.15Å; W123-F130 AromaticContact CG-CD2 3.94Å; W123-F130 HydrophobicContact CG-CD2 3.94Å; W123-A133 HydrophobicContact CB-CB 4.02Å; W123-A133 HydrophobicContact CE3-CB 4.13Å; W123-G139 WeakPolarHBondContact CA-O 3.41Å; W123-L140 HydrophobicContact CB-CD2 3.7Å
124N98.6Very high98.4Very high3 Ų328.3 Ų28.32%0.01616%0.161CC..EExtended strand (participates in β ladder)trans-72.5119.8-173.1-172.4-21.6000111.7F86 H88 K126 Y127 D138 G139F86-N124 WeakPolarHBondContact CB-OD1 3.46Å; H88-N124 PolarHBondContact CD2-N 3.22Å; H88-N124 VanDerWaalsContact CD2-N 3.34Å; H88-N124 VanDerWaalsContact NE2-CB 3.33Å; H88-N124 WeakPolarHBondContact NE2-CB 3.43Å; N124-K126 PolarHBondContact O-N 3.3Å; N124-K126 VanDerWaalsContact O-N 3.09Å; N124-K126 WeakPolarHBondContact OD1-CB 3.38Å; N124-K126 PolarHBondContact OD1-N 2.84Å; N124-Y127 HydrophobicContact CB-CD2 3.98Å; N124-Y127 HydrophobicContact CB-CE2 4.22Å; N124-Y127 PolarHBondContact O-N 2.74Å; N124-Y127 VanDerWaalsContact O-N 3.13Å; N124-D138 WeakPolarHBondContact CB-O 3.23Å; N124-D138 PolarHBondContact ND2-O 3.41Å; N124-G139 WeakPolarHBondContact CB-O 3.46Å; N124-G139 PolarHBondContact N-O 2.91Å
125T98.2Very high98.2Very high43 Ų4329.6 Ų29.626%0.26418%0.177SC..THydrogen-bonded Turntrans-73-0.7-176.7670000114.1N87 R89 W123 Y127N87-T125 HydrophobicContact CB-CG2 4.39Å; N87-T125 WeakPolarHBondContact O-CG2 3.38Å; N87-T125 PolarHBondContact O-N 2.88Å; N87-T125 PolarHBondContact O-OG1 2.97Å; N87-T125 VanDerWaalsContact O-OG1 3.11Å; R89-T125 HydrophobicContact CB-CG2 4.45Å; R89-T125 HydrophobicContact CG-CG2 3.6Å; W123-T125 PolarHBondContact O-N 2.79Å; T125-Y127 PolarHBondContact O-N 2.92Å
126K98Very high98.2Very high105 Ų10532.3 Ų32.346%0.45719%0.189SC..THydrogen-bonded Turntrans-62-28.3165.6174.6-174162.5-151.40111.9F86 N124 D138F86-K126 HydrophobicContact CD1-CB 4.49Å; F86-K126 HydrophobicContact CD2-CB 4.47Å; F86-K126 HydrophobicContact CD2-CD 4.12Å; F86-K126 HydrophobicContact CE2-CD 3.83Å; F86-K126 HydrophobicContact CG-CB 4.31Å; F86-K126 HydrophobicContact CZ-CD 4.14Å; N124-K126 PolarHBondContact O-N 3.3Å; N124-K126 VanDerWaalsContact O-N 3.09Å; N124-K126 WeakPolarHBondContact OD1-CB 3.38Å; N124-K126 PolarHBondContact OD1-N 2.84Å; K126-D138 IonicContact NZ-OD1 2.71Å; K126-D138 IonicContact NZ-OD2 2.78Å; K126-D138 PolarHBondContact NZ-OD2 3.25Å
127Y98.3Very high98.1Very high23 Ų2335.4 Ų35.49%0.0921%0.209CC..SBendtrans-94.9161.5177.6-58.5-68.3000110.9W123 N124 T125 N129 E132 A133 Q136 D138W123-Y127 WeakPolarHBondContact CZ3-O 3.47Å; N124-Y127 HydrophobicContact CB-CD2 3.98Å; N124-Y127 HydrophobicContact CB-CE2 4.22Å; N124-Y127 PolarHBondContact O-N 2.74Å; N124-Y127 VanDerWaalsContact O-N 3.13Å; T125-Y127 PolarHBondContact O-N 2.92Å; Y127-N129 PolarHBondContact O-N 3.19Å; Y127-E132 HydrophobicContact CD1-CG 4.23Å; Y127-A133 HydrophobicContact CD2-CB 3.86Å; Y127-A133 HydrophobicContact CG-CB 4.17Å; Y127-Q136 HydrophobicContact CD1-CG 3.84Å; Y127-Q136 HydrophobicContact CD2-CB 4.42Å; Y127-Q136 HydrophobicContact CD2-CG 4.38Å; Y127-Q136 HydrophobicContact CE1-CB 3.97Å; Y127-Q136 HydrophobicContact CE1-CG 3.4Å; Y127-Q136 VanDerWaalsContact CE1-CG 3.4Å; Y127-Q136 HydrophobicContact CE2-CB 3.75Å; Y127-Q136 HydrophobicContact CE2-CG 4.01Å; Y127-Q136 HydrophobicContact CG-CG 4.31Å; Y127-Q136 VanDerWaalsContact CZ-CB 3.47Å; Y127-Q136 VanDerWaalsContact CZ-CG 3.49Å; Y127-D138 PolarHBondContact OH-OD1 2.86Å
128A97.3Very high98Very high76 Ų7637.7 Ų37.763%0.62822%0.221SC*.SBendtrans-73.7-27.6-172.400000113.5E132A128-E132 WeakPolarHBondContact CB-OE2 3.12Å; A128-E132 PolarHBondContact N-OE2 2.65Å
129N97.6Very high97.9Very high80 Ų8037.7 Ų37.743%0.42822%0.221SC..SBendtrans-162.3170.1-178.457.876.1000111.2Y127 G131 E132 A133Y127-N129 PolarHBondContact O-N 3.19Å; N129-G131 VanDerWaalsContact C-N 3.29Å; N129-G131 PolarHBondContact O-N 3.42Å; N129-G131 WeakPolarHBondContact OD1-CA 3.34Å; N129-G131 PolarHBondContact OD1-N 3.38Å; N129-E132 PolarHBondContact O-N 3.48Å; N129-E132 PolarHBondContact OD1-N 2.89Å; N129-A133 WeakPolarHBondContact O-CB 2.94Å; N129-A133 PolarHBondContact O-N 3.04Å
130F97.8Very high97.9Very high59 Ų5937.6 Ų37.626%0.25922%0.221SC..Hα-helixtrans-52-42.8177.5-179.2-88.2000113.6K91 V121 W123 A133 A134 L140K91-F130 HydrophobicContact CB-CD2 3.96Å; K91-F130 HydrophobicContact CB-CE2 4.13Å; K91-F130 HydrophobicContact CD-CD2 4.47Å; K91-F130 HydrophobicContact CG-CD2 3.82Å; K91-F130 HydrophobicContact CG-CE2 4.07Å; K91-F130 HydrophobicContact CG-CG 4.38Å; V121-F130 HydrophobicContact CG1-CE2 4.05Å; W123-F130 HydrophobicContact CB-CD2 3.76Å; W123-F130 HydrophobicContact CB-CE2 4.45Å; W123-F130 AromaticContact CD1-CD2 3.82Å; W123-F130 HydrophobicContact CD2-CB 4.46Å; W123-F130 HydrophobicContact CG-CB 4.15Å; W123-F130 AromaticContact CG-CD2 3.94Å; W123-F130 HydrophobicContact CG-CD2 3.94Å; F130-A133 PolarHBondContact O-N 3.26Å; F130-A134 HydrophobicContact CE1-CB 4.19Å; F130-A134 VanDerWaalsContact O-CB 3.29Å; F130-A134 WeakPolarHBondContact O-CB 3.21Å; F130-A134 PolarHBondContact O-N 3.47Å; F130-L140 HydrophobicContact CD2-CD2 4.11Å; F130-L140 HydrophobicContact CE2-CD2 3.69Å; F130-L140 HydrophobicContact CZ-CD1 4.48Å; F130-L140 HydrophobicContact CZ-CD2 4.21Å
131G96.8Very high97.9Very high48 Ų4837.6 Ų37.650%0.49522%0.221SC..Hα-helixtrans-65.9-42.4-176.500000112.6N129N129-G131 VanDerWaalsContact C-N 3.29Å; N129-G131 PolarHBondContact O-N 3.42Å; N129-G131 WeakPolarHBondContact OD1-CA 3.34Å; N129-G131 PolarHBondContact OD1-N 3.38Å
132E97.9Very high97.9Very high81 Ų8137.6 Ų37.638%0.37922%0.221SC..Hα-helixtrans-64.4-49.2172.2-172.9-175.9168.600110.6Y127 A128 N129 A134 S135 Q136Y127-E132 HydrophobicContact CD1-CG 4.23Å; A128-E132 WeakPolarHBondContact CB-OE2 3.12Å; A128-E132 PolarHBondContact N-OE2 2.65Å; N129-E132 PolarHBondContact O-N 3.48Å; N129-E132 PolarHBondContact OD1-N 2.89Å; E132-A134 PolarHBondContact O-N 3.03Å; E132-S135 PolarHBondContact O-N 2.93Å; E132-S135 VanDerWaalsContact O-N 3.14Å; E132-S135 PolarHBondContact O-OG 3.46Å; E132-Q136 WeakPolarHBondContact O-CG 3.16Å
133A98.4Very high97.9Very high0 Ų037.6 Ų37.60%022%0.221CC..Hα-helixtrans-56.4-48.2179.600000111.6W123 Y127 N129 F130 S135 Q136 G139W123-A133 HydrophobicContact CB-CB 4.02Å; W123-A133 HydrophobicContact CE3-CB 4.13Å; Y127-A133 HydrophobicContact CD2-CB 3.86Å; Y127-A133 HydrophobicContact CG-CB 4.17Å; N129-A133 WeakPolarHBondContact O-CB 2.94Å; N129-A133 PolarHBondContact O-N 3.04Å; F130-A133 PolarHBondContact O-N 3.26Å; A133-S135 PolarHBondContact O-N 3.3Å; A133-Q136 WeakPolarHBondContact O-CB 3.37Å; A133-Q136 PolarHBondContact O-N 2.75Å; A133-G139 WeakPolarHBondContact CB-O 3.36Å; A133-G139 WeakPolarHBondContact O-CA 3.32Å
134A97.4Very high97.9Very high9 Ų937.2 Ų37.27%0.07422%0.22CC..Hα-helixtrans-57.8-21.1-178.700000114.2F130 E132 L140 L203 S205F130-A134 HydrophobicContact CE1-CB 4.19Å; F130-A134 VanDerWaalsContact O-CB 3.29Å; F130-A134 WeakPolarHBondContact O-CB 3.21Å; F130-A134 PolarHBondContact O-N 3.47Å; E132-A134 PolarHBondContact O-N 3.03Å; A134-L140 HydrophobicContact CB-CD1 4.11Å; A134-L140 HydrophobicContact CB-CD2 4.33Å; A134-L140 HydrophobicContact CB-CG 4.43Å; A134-L203 HydrophobicContact CB-CD1 4.44Å; A134-L203 VanDerWaalsContact O-CD1 3.26Å; A134-L203 WeakPolarHBondContact O-CD1 3.48Å; A134-S205 WeakPolarHBondContact O-CB 3.4Å; A134-S205 PolarHBondContact O-OG 3.4Å
135S96.1Very high98Very high74 Ų7437.1 Ų37.152%0.51722%0.219SC..THydrogen-bonded Turntrans-85.7-2.4175.874.70000114.6E132 A133E132-S135 PolarHBondContact O-N 2.93Å; E132-S135 VanDerWaalsContact O-N 3.14Å; E132-S135 PolarHBondContact O-OG 3.46Å; A133-S135 PolarHBondContact O-N 3.3Å
136Q98.3Very high98Very high63 Ų6335 Ų3529%0.29421%0.206SC..SBendtrans-112144.5-170.3-58.8-70.3-33.400111Y127 E132 A133 D138 G139 S205Y127-Q136 HydrophobicContact CD1-CG 3.84Å; Y127-Q136 HydrophobicContact CD2-CB 4.42Å; Y127-Q136 HydrophobicContact CD2-CG 4.38Å; Y127-Q136 HydrophobicContact CE1-CB 3.97Å; Y127-Q136 HydrophobicContact CE1-CG 3.4Å; Y127-Q136 VanDerWaalsContact CE1-CG 3.4Å; Y127-Q136 HydrophobicContact CE2-CB 3.75Å; Y127-Q136 HydrophobicContact CE2-CG 4.01Å; Y127-Q136 HydrophobicContact CG-CG 4.31Å; Y127-Q136 VanDerWaalsContact CZ-CB 3.47Å; Y127-Q136 VanDerWaalsContact CZ-CG 3.49Å; E132-Q136 WeakPolarHBondContact O-CG 3.16Å; A133-Q136 WeakPolarHBondContact O-CB 3.37Å; A133-Q136 PolarHBondContact O-N 2.75Å; Q136-D138 VanDerWaalsContact C-N 3.27Å; Q136-D138 PolarHBondContact O-N 2.76Å; Q136-G139 PolarHBondContact O-N 2.82Å; Q136-S205 VanDerWaalsContact O-CA 3.23Å; Q136-S205 WeakPolarHBondContact O-CA 3.47Å; Q136-S205 WeakPolarHBondContact O-CB 3.28Å
137P96.1Very high98Very high66 Ų6630 Ų3043%0.42918%0.184SC..THydrogen-bonded Turntrans-63.5-27.6-172.625.4-35.2000114.7
138D96.9Very high98.1Very high48 Ų4833.4 Ų33.426%0.25720%0.199SC..THydrogen-bonded Turntrans-110.926176.261.8-39.6000111.6N124 K126 Y127 Q136N124-D138 WeakPolarHBondContact CB-O 3.23Å; N124-D138 PolarHBondContact ND2-O 3.41Å; K126-D138 IonicContact NZ-OD1 2.71Å; K126-D138 IonicContact NZ-OD2 2.78Å; K126-D138 PolarHBondContact NZ-OD2 3.25Å; Y127-D138 PolarHBondContact OH-OD1 2.86Å; Q136-D138 VanDerWaalsContact C-N 3.27Å; Q136-D138 PolarHBondContact O-N 2.76Å
139G98.5Very high98.1Very high0 Ų033 Ų330%019%0.186CC..SBendtrans-80.6-34.5-167.700000115W123 N124 A133 Q136 S205W123-G139 WeakPolarHBondContact CA-O 3.41Å; N124-G139 WeakPolarHBondContact CB-O 3.46Å; N124-G139 PolarHBondContact N-O 2.91Å; A133-G139 WeakPolarHBondContact CB-O 3.36Å; A133-G139 WeakPolarHBondContact O-CA 3.32Å; Q136-G139 PolarHBondContact O-N 2.82Å; G139-S205 PolarHBondContact N-O 2.94Å
140L98.9Very high98.2Very high0 Ų031 Ų310%018%0.184CC..EExtended strand (participates in β ladder)trans-123.6149.1-175.5-55.8-179.9000110.5H122 W123 F130 A134 L197 S205 V206 T207H122-L140 CarbonylContact O-C 3.49Å; H122-L140 VanDerWaalsContact O-CA 3.28Å; H122-L140 WeakPolarHBondContact O-CA 3.4Å; W123-L140 HydrophobicContact CB-CD2 3.7Å; F130-L140 HydrophobicContact CD2-CD2 4.11Å; F130-L140 HydrophobicContact CE2-CD2 3.69Å; F130-L140 HydrophobicContact CZ-CD1 4.48Å; F130-L140 HydrophobicContact CZ-CD2 4.21Å; A134-L140 HydrophobicContact CB-CD1 4.11Å; A134-L140 HydrophobicContact CB-CD2 4.33Å; A134-L140 HydrophobicContact CB-CG 4.43Å; L140-L197 HydrophobicContact CD1-CD2 3.77Å; L140-L197 HydrophobicContact CD1-CG 4.37Å; L140-S205 WeakPolarHBondContact CB-O 3.48Å; L140-S205 PolarHBondContact N-O 2.85Å; L140-V206 HydrophobicContact CB-CG2 4.09Å; L140-V206 HydrophobicContact CD1-CG2 4.15Å; L140-V206 WeakPolarHBondContact O-CA 3.43Å; L140-T207 PolarHBondContact O-N 2.99Å
141A98.9Very high98.2Very high0 Ų035.8 Ų35.80%021%0.207CC..EExtended strand (participates in β ladder)trans-128.5128.7168.200000108.9L79 V84 H122 T207L79-A141 HydrophobicContact CD2-CB 3.7Å; V84-A141 HydrophobicContact CG1-CB 3.74Å; H122-A141 WeakPolarHBondContact CA-O 3.29Å; H122-A141 WeakPolarHBondContact CB-O 3.26Å; H122-A141 PolarHBondContact N-O 3.03Å; H122-A141 PolarHBondContact ND1-O 3.1Å; H122-A141 PolarHBondContact O-N 2.92Å; A141-T207 WeakPolarHBondContact CA-O 3.09Å
142V98.9Very high98.2Very high4 Ų439 Ų392%0.02421%0.21CC..EExtended strand (participates in β ladder)trans-119.5122.1-178.6-178.50000109.6H119 L120 V121 V206 T207 W208 I209H119-V142 HydrophobicContact CB-CG1 3.74Å; L120-V142 WeakPolarHBondContact O-CA 3.22Å; V121-V142 HydrophobicContact CB-CG2 4.48Å; V121-V142 HydrophobicContact CG1-CG2 4.3Å; V121-V142 HydrophobicContact CG2-CG2 4.15Å; V142-V206 HydrophobicContact CB-CG1 3.88Å; V142-V206 HydrophobicContact CG2-CG1 3.54Å; V142-T207 PolarHBondContact N-O 2.93Å; V142-T207 VanDerWaalsContact N-O 3.1Å; V142-W208 HydrophobicContact CB-CD2 4.39Å; V142-W208 HydrophobicContact CB-CE3 4.06Å; V142-W208 HydrophobicContact CB-CH2 4.05Å; V142-W208 HydrophobicContact CB-CZ2 4.4Å; V142-W208 HydrophobicContact CB-CZ3 3.9Å; V142-W208 HydrophobicContact CG1-CE3 4.02Å; V142-W208 HydrophobicContact CG1-CH2 3.56Å; V142-W208 HydrophobicContact CG1-CZ2 4.35Å; V142-W208 HydrophobicContact CG1-CZ3 3.39Å; V142-I209 PolarHBondContact O-N 3.05Å
143V98.9Very high98.3Very high0 Ų035.9 Ų35.90%020%0.195CC..EExtended strand (participates in β ladder)trans-89.2112.8169.5-177.70000108L79 L120 V145 L184 I209L79-V143 HydrophobicContact CD2-CG2 4.2Å; L120-V143 HydrophobicContact CB-CB 4.18Å; L120-V143 HydrophobicContact CD1-CB 4.24Å; L120-V143 HydrophobicContact CD1-CG1 4.37Å; L120-V143 PolarHBondContact N-O 3.22Å; L120-V143 PolarHBondContact O-N 3.06Å; V143-V145 HydrophobicContact CG1-CG2 4.32Å; V143-L184 HydrophobicContact CG1-CD2 4.28Å; V143-I209 CarbonylContact C-O 3.48Å; V143-I209 VanDerWaalsContact CA-O 3.28Å; V143-I209 WeakPolarHBondContact CA-O 3.23Å; V143-I209 HydrophobicContact CG2-CB 4.3Å; V143-I209 HydrophobicContact CG2-CD1 4.35Å; V143-I209 HydrophobicContact CG2-CG2 4.33Å
144G98.9Very high98.2Very high0 Ų040.1 Ų40.10%022%0.223CC..EExtended strand (participates in β ladder)trans-96128177.300000111L118 I209 C211L118-G144 CarbonylContact O-C 3.6Å; L118-G144 VanDerWaalsContact O-CA 3.27Å; L118-G144 WeakPolarHBondContact O-CA 3.46Å; G144-I209 PolarHBondContact N-O 3.22Å; G144-C211 PolarHBondContact O-N 2.8Å
145V98.9Very high98.2Very high0 Ų042.5 Ų42.50%024%0.235CC..EExtended strand (participates in β ladder)trans-126.3121.8177.3-177.80000109.3E117 L118 V143 L184 C211 I215E117-V145 WeakPolarHBondContact CA-O 3.42Å; L118-V145 HydrophobicContact CB-CB 4.19Å; L118-V145 HydrophobicContact CD2-CB 4.26Å; L118-V145 HydrophobicContact CD2-CG2 4.39Å; L118-V145 PolarHBondContact N-O 3.45Å; L118-V145 PolarHBondContact O-N 3.04Å; V143-V145 HydrophobicContact CG1-CG2 4.32Å; V145-L184 HydrophobicContact CG2-CD2 4.12Å; V145-C211 HydrophobicContact CG2-CB 4.32Å; V145-I215 HydrophobicContact CG1-CB 4.5Å; V145-I215 HydrophobicContact CG1-CD1 4.41Å; V145-I215 HydrophobicContact CG1-CG1 4.12Å; V145-I215 HydrophobicContact CG1-CG2 3.86Å
146F98.9Very high98.3Very high0 Ų039 Ų390%021%0.21CC..EExtended strand (participates in β ladder)trans-72.3144.6173.5-64.5-61.6000111.2H107 V109 Y114 E117 V210 P214 I215H107-F146 HydrophobicContact CB-CE1 3.75Å; H107-F146 HydrophobicContact CB-CZ 3.6Å; H107-F146 WeakPolarHBondContact O-CE1 3.36Å; V109-F146 HydrophobicContact CG2-CE2 3.71Å; V109-F146 HydrophobicContact CG2-CZ 3.96Å; Y114-F146 HydrophobicContact CD1-CB 3.97Å; Y114-F146 HydrophobicContact CD2-CB 3.86Å; Y114-F146 AromaticContact CD2-CD1 3.44Å; Y114-F146 HydrophobicContact CD2-CD1 3.44Å; Y114-F146 VanDerWaalsContact CD2-CD1 3.44Å; Y114-F146 HydrophobicContact CD2-CD2 4.14Å; Y114-F146 AromaticContact CD2-CE1 3.95Å; Y114-F146 HydrophobicContact CD2-CE1 3.95Å; Y114-F146 AromaticContact CD2-CG 3.54Å; Y114-F146 HydrophobicContact CD2-CG 3.54Å; Y114-F146 HydrophobicContact CD2-CZ 4.48Å; Y114-F146 HydrophobicContact CE1-CB 4.28Å; Y114-F146 HydrophobicContact CE2-CB 4.18Å; Y114-F146 HydrophobicContact CE2-CD1 4.07Å; Y114-F146 AromaticContact CE2-CD2 3.92Å; Y114-F146 HydrophobicContact CE2-CD2 3.92Å; Y114-F146 HydrophobicContact CE2-CE1 4.43Å; Y114-F146 HydrophobicContact CE2-CE2 4.29Å; Y114-F146 AromaticContact CE2-CG 3.79Å; Y114-F146 HydrophobicContact CE2-CG 3.79Å; Y114-F146 HydrophobicContact CG-CB 3.76Å; Y114-F146 AromaticContact CG-CD1 3.94Å; Y114-F146 HydrophobicContact CG-CD1 3.94Å; Y114-F146 AromaticContact CG-CG 3.96Å; Y114-F146 HydrophobicContact CG-CG 3.96Å; E117-F146 HydrophobicContact CG-CD1 4.14Å; E117-F146 HydrophobicContact CG-CE1 4.32Å; E117-F146 WeakPolarHBondContact OE2-CE1 3.41Å; F146-V210 HydrophobicContact CD2-CG1 4.41Å; F146-V210 HydrophobicContact CE2-CG1 3.57Å; F146-V210 HydrophobicContact CZ-CG1 3.78Å; F146-P214 HydrophobicContact CB-CB 3.83Å; F146-P214 CarbonylContact O-C 3.58Å; F146-P214 WeakPolarHBondContact O-CA 3.34Å; F146-P214 WeakPolarHBondContact O-CB 3.44Å; F146-I215 PolarHBondContact O-N 2.83Å
147L98.9Very high98.2Very high0 Ų038.5 Ų38.50%021%0.208CC..EExtended strand (participates in β ladder)trans-105.7136.5169.4-70.778.4000108.4F95 Y114 P115 A116 L118 L156 I215 V217F95-L147 HydrophobicContact CD1-CD1 3.93Å; F95-L147 HydrophobicContact CD1-CD2 4.28Å; F95-L147 HydrophobicContact CE1-CD1 3.87Å; F95-L147 HydrophobicContact CE1-CD2 3.96Å; Y114-L147 VanDerWaalsContact CB-O 3.32Å; Y114-L147 WeakPolarHBondContact CB-O 3.34Å; P115-L147 WeakPolarHBondContact CD-O 3.42Å; P115-L147 WeakPolarHBondContact CG-O 3.35Å; A116-L147 HydrophobicContact CB-CB 4.08Å; A116-L147 HydrophobicContact CB-CD1 4.03Å; A116-L147 HydrophobicContact CB-CD2 4.15Å; A116-L147 HydrophobicContact CB-CG 4.3Å; A116-L147 PolarHBondContact O-N 2.9Å; L118-L147 HydrophobicContact CB-CD1 4.19Å; L147-L156 HydrophobicContact CD2-CD1 3.93Å; L147-I215 CarbonylContact C-O 3.59Å; L147-I215 WeakPolarHBondContact CA-O 3.26Å; L147-I215 HydrophobicContact CG-CD1 4.1Å; L147-I215 HydrophobicContact CG-CG1 3.9Å; L147-V217 HydrophobicContact CB-CB 4.49Å; L147-V217 HydrophobicContact CB-CG1 3.83Å; L147-V217 HydrophobicContact CD2-CB 4.08Å; L147-V217 HydrophobicContact CD2-CG1 4.11Å; L147-V217 HydrophobicContact CD2-CG2 4.32Å
148K98.6Very high98.3Very high93 Ų9339.2 Ų39.240%0.40420%0.204SC..EExtended strand (participates in β ladder)trans-121.4148.1173.763.3172.8172.8-170.70110.7Y114 G150 P214 I215 S216 V217Y114-K148 HydrophobicContact CD1-CB 4.05Å; Y114-K148 HydrophobicContact CE1-CB 4.26Å; K148-G150 PolarHBondContact O-N 3.04Å; K148-P214 HydrophobicContact CB-CB 4.24Å; K148-P214 HydrophobicContact CB-CG 4.36Å; K148-P214 HydrophobicContact CD-CB 4.23Å; K148-P214 HydrophobicContact CD-CG 3.58Å; K148-P214 HydrophobicContact CG-CB 4.03Å; K148-P214 HydrophobicContact CG-CG 3.95Å; K148-I215 PolarHBondContact N-O 2.97Å; K148-S216 CarbonylContact O-C 3.53Å; K148-S216 WeakPolarHBondContact O-CA 3.33Å; K148-V217 PolarHBondContact O-N 2.84Å
149I98.8Very high98.3Very high67 Ų6737 Ų3734%0.34419%0.192SC..EExtended strand (participates in β ladder)trans-62.6131.2172.5-58.4-52.4000110.1D101 P115 V217 M222D101-I149 HydrophobicContact CB-CD1 3.92Å; D101-I149 HydrophobicContact CB-CG1 3.7Å; D101-I149 VanDerWaalsContact CG-CD1 3.46Å; P115-I149 HydrophobicContact CB-CD1 4.14Å; P115-I149 HydrophobicContact CG-CD1 3.93Å; P115-I149 HydrophobicContact CG-CG1 4.12Å; I149-V217 WeakPolarHBondContact CA-O 3.13Å; I149-V217 HydrophobicContact CD1-CG1 4.29Å; I149-M222 HydrophobicContact CD1-CG 3.91Å
150G98.4Very high98.3Very high38 Ų3837.4 Ų37.439%0.39220%0.195SC..SBendtrans-174.7-143.2177.700000110.4K148 S216 V217K148-G150 PolarHBondContact O-N 3.04Å; G150-S216 WeakPolarHBondContact CA-OG 3.4Å; G150-V217 PolarHBondContact N-O 3.21Å
151E98.1Very high98.2Very high160 Ų16042.2 Ų42.275%0.74822%0.221SC*.SBendtrans-63.6153174-61.2-59.3137.500111.6N153 S216 V217E151-N153 PolarHBondContact O-N 3.02Å; E151-S216 PolarHBondContact N-OG 3.43Å; E151-S216 PolarHBondContact O-OG 3.08Å; E151-V217 CarbonylContact O-C 3.52Å
152E98.3Very high98.2Very high116 Ų11644.8 Ų44.854%0.54223%0.232SC..  trans-53.3135170.3-175.1-179.897.500110.3P154 Q221E152-P154 VanDerWaalsContact O-CD 3.3Å; E152-P154 WeakPolarHBondContact O-CD 3.3Å; E152-Q221 HydrophobicContact CG-CG 4.35Å
153N98.3Very high98.2Very high15 Ų1544.6 Ų44.68%0.0823%0.232CC..  trans-99.6104.3176.9-172.1-17.8000109.6E151 N155 L156 S216 Q221E151-N153 PolarHBondContact O-N 3.02Å; N153-N155 PolarHBondContact O-N 3.4Å; N153-N155 VanDerWaalsContact O-N 3.08Å; N153-N155 VanDerWaalsContact OD1-CB 3.22Å; N153-N155 WeakPolarHBondContact OD1-CB 3.17Å; N153-N155 PolarHBondContact OD1-N 3.18Å; N153-L156 HydrophobicContact CB-CB 4.42Å; N153-L156 HydrophobicContact CB-CD1 3.98Å; N153-L156 HydrophobicContact CB-CG 4.19Å; N153-L156 PolarHBondContact O-N 2.83Å; N153-S216 WeakPolarHBondContact CB-O 3.23Å; N153-S216 PolarHBondContact ND2-O 2.93Å; N153-Q221 PolarHBondContact O-NE2 3.27Å
154P97.9Very high98.1Very high90 Ų9050 Ų5058%0.58426%0.261SS*.Hα-helixtrans-61.7-22.7-178.425.4-34.9000112.2E152 L156 Q157E152-P154 VanDerWaalsContact O-CD 3.3Å; E152-P154 WeakPolarHBondContact O-CD 3.3Å; P154-L156 VanDerWaalsContact C-N 3.28Å; P154-L156 PolarHBondContact O-N 2.66Å; P154-Q157 WeakPolarHBondContact O-CB 3.43Å; P154-Q157 PolarHBondContact O-N 2.71Å
155N96.9Very high98.1Very high59 Ų5953.3 Ų53.332%0.31628%0.284SS..Hα-helixtrans-73-21.6179.1-60.8-22.7000113N153 M182 L183N153-N155 PolarHBondContact O-N 3.4Å; N153-N155 VanDerWaalsContact O-N 3.08Å; N153-N155 VanDerWaalsContact OD1-CB 3.22Å; N153-N155 WeakPolarHBondContact OD1-CB 3.17Å; N153-N155 PolarHBondContact OD1-N 3.18Å; N155-M182 HydrophobicContact CB-CB 4.03Å; N155-M182 HydrophobicContact CB-CE 3.79Å; N155-M182 HydrophobicContact CB-CG 3.86Å; N155-M182 VanDerWaalsContact CB-O 3.3Å; N155-M182 WeakPolarHBondContact CB-O 3.26Å; N155-M182 HydrophobicContact CB-SD 4.48Å; N155-M182 PolarHBondContact ND2-O 2.83Å; N155-M182 WeakPolarHBondContact OD1-CE 3.38Å; N155-L183 HydrophobicContact CB-CD2 4.15Å
156L97.8Very high98.1Very high0 Ų053.3 Ų53.30%028%0.284CS..Hα-helixtrans-84.8-16.8172.3-70.4173.8000112.5F95 L147 N153 P154 K158 L159 V160 L183 V217F95-L156 HydrophobicContact CE1-CD2 4.19Å; F95-L156 HydrophobicContact CZ-CD2 3.83Å; L147-L156 HydrophobicContact CD2-CD1 3.93Å; N153-L156 HydrophobicContact CB-CB 4.42Å; N153-L156 HydrophobicContact CB-CD1 3.98Å; N153-L156 HydrophobicContact CB-CG 4.19Å; N153-L156 PolarHBondContact O-N 2.83Å; P154-L156 VanDerWaalsContact C-N 3.28Å; P154-L156 PolarHBondContact O-N 2.66Å; L156-K158 VanDerWaalsContact C-N 3.34Å; L156-K158 PolarHBondContact O-N 2.8Å; L156-L159 HydrophobicContact CD2-CD1 4.16Å; L156-L159 WeakPolarHBondContact O-CB 3.44Å; L156-L159 PolarHBondContact O-N 3.14Å; L156-V160 WeakPolarHBondContact O-CG2 3.48Å; L156-V160 PolarHBondContact O-N 3.02Å; L156-V160 VanDerWaalsContact O-N 3.1Å; L156-L183 HydrophobicContact CD2-CD2 3.58Å; L156-L183 HydrophobicContact CG-CD2 4.14Å; L156-V217 HydrophobicContact CD1-CB 4.02Å; L156-V217 HydrophobicContact CD1-CG2 3.71Å
157Q97.4Very high98.1Very high53 Ų5357.1 Ų57.125%0.24830%0.3CS..Hα-helixtrans-64.1-40.1-168-166.155.94000112.6P154 L159 V160 D161P154-Q157 WeakPolarHBondContact O-CB 3.43Å; P154-Q157 PolarHBondContact O-N 2.71Å; Q157-L159 PolarHBondContact O-N 3.21Å; Q157-V160 PolarHBondContact O-N 3.07Å; Q157-V160 VanDerWaalsContact O-N 3.07Å; Q157-D161 PolarHBondContact NE2-OD1 2.8Å; Q157-D161 PolarHBondContact O-N 3.34Å
158K96.3Very high98Very high81 Ų8158.6 Ų58.635%0.35231%0.309SS..Hα-helixtrans-59-29.8176.1-177.5170.5165.6179.20112.7L156 F175 A176 D177 F178L156-K158 VanDerWaalsContact C-N 3.34Å; L156-K158 PolarHBondContact O-N 2.8Å; K158-F175 HydrophobicContact CD-CE2 4.37Å; K158-F175 HydrophobicContact CD-CZ 4.3Å; K158-F175 HydrophobicContact CG-CE2 3.73Å; K158-F175 HydrophobicContact CG-CZ 3.82Å; K158-F175 WeakPolarHBondContact O-CE2 3.22Å; K158-A176 PolarHBondContact NZ-O 2.9Å; K158-D177 PolarHBondContact NZ-O 2.81Å; K158-F178 HydrophobicContact CB-CE2 4.41Å; K158-F178 HydrophobicContact CD-CD2 4.02Å; K158-F178 HydrophobicContact CG-CD2 4.37Å
159L97.6Very high98Very high0 Ų057.8 Ų57.80%031%0.305CS..Hα-helixtrans-75.5-47.3173.3-65.7167.5000111.3I59 F66 V68 F93 F95 L156 Q157 D161 E162 F163 F175 F178 L183I59-L159 HydrophobicContact CD1-CD2 4.24Å; F66-L159 HydrophobicContact CE2-CD2 4.49Å; V68-L159 HydrophobicContact CG2-CD2 3.71Å; F93-L159 HydrophobicContact CE2-CD1 3.93Å; F93-L159 HydrophobicContact CE2-CD2 4.11Å; F93-L159 HydrophobicContact CZ-CD1 4.07Å; F93-L159 HydrophobicContact CZ-CD2 3.87Å; F95-L159 HydrophobicContact CE2-CD1 4.17Å; F95-L159 HydrophobicContact CZ-CD1 4.35Å; L156-L159 HydrophobicContact CD2-CD1 4.16Å; L156-L159 WeakPolarHBondContact O-CB 3.44Å; L156-L159 PolarHBondContact O-N 3.14Å; Q157-L159 PolarHBondContact O-N 3.21Å; L159-D161 PolarHBondContact O-N 2.98Å; L159-E162 PolarHBondContact O-N 3.24Å; L159-F163 HydrophobicContact CB-CE1 4.37Å; L159-F163 WeakPolarHBondContact O-CD1 3.14Å; L159-F163 VanDerWaalsContact O-CE1 3.32Å; L159-F163 WeakPolarHBondContact O-CE1 3.46Å; L159-F175 HydrophobicContact CD2-CE1 3.58Å; L159-F175 HydrophobicContact CD2-CE2 4.35Å; L159-F175 HydrophobicContact CD2-CZ 3.46Å; L159-F175 VanDerWaalsContact CD2-CZ 3.46Å; L159-F175 HydrophobicContact CG-CZ 4.18Å; L159-F178 HydrophobicContact CD1-CZ 4.11Å; L159-F178 HydrophobicContact CG-CE2 4.22Å; L159-F178 HydrophobicContact CG-CZ 4.17Å; L159-L183 HydrophobicContact CD1-CD1 4.06Å
160V98.1Very high98Very high10 Ų1059.9 Ų59.96%0.06132%0.317CS..Hα-helixtrans-59.1-36.6-178.1170.60000111.4L156 Q157 E162 F163 Q221 K224 F225L156-V160 WeakPolarHBondContact O-CG2 3.48Å; L156-V160 PolarHBondContact O-N 3.02Å; L156-V160 VanDerWaalsContact O-N 3.1Å; Q157-V160 PolarHBondContact O-N 3.07Å; Q157-V160 VanDerWaalsContact O-N 3.07Å; V160-E162 PolarHBondContact O-N 3.01Å; V160-F163 HydrophobicContact CG2-CE2 4.32Å; V160-F163 WeakPolarHBondContact O-CB 3.38Å; V160-F163 PolarHBondContact O-N 3.13Å; V160-Q221 HydrophobicContact CG2-CG 4.38Å; V160-K224 HydrophobicContact CG1-CB 3.75Å; V160-K224 HydrophobicContact CG1-CD 4.44Å; V160-K224 HydrophobicContact CG1-CG 3.7Å; V160-F225 HydrophobicContact CG2-CE2 4.01Å
161D98Very high98Very high101 Ų10159.2 Ų59.254%0.5431%0.307SS..THydrogen-bonded Turntrans-63.5-23.2178.3-66.6-19.5000112.8Q157 L159Q157-D161 PolarHBondContact NE2-OD1 2.8Å; Q157-D161 PolarHBondContact O-N 3.34Å; L159-D161 PolarHBondContact O-N 2.98Å
162E98.3Very high98Very high53 Ų5357 Ų5725%0.24830%0.297CS..THydrogen-bonded Turntrans-89.5-9.1178.6-62.8-58.9153.800113.8I59 L159 V160 D164 S165 I166 C173 F175I59-E162 HydrophobicContact CD1-CB 4.4Å; I59-E162 HydrophobicContact CG2-CB 4.17Å; I59-E162 HydrophobicContact CG2-CG 4.47Å; L159-E162 PolarHBondContact O-N 3.24Å; V160-E162 PolarHBondContact O-N 3.01Å; E162-D164 VanDerWaalsContact C-N 3.27Å; E162-D164 PolarHBondContact O-N 2.85Å; E162-S165 WeakPolarHBondContact O-CA 3.27Å; E162-S165 VanDerWaalsContact O-CB 3.31Å; E162-S165 WeakPolarHBondContact O-CB 3.41Å; E162-S165 PolarHBondContact O-N 3.44Å; E162-I166 WeakPolarHBondContact O-CG1 3.04Å; E162-I166 PolarHBondContact O-N 2.95Å; E162-C173 PolarHBondContact OE2-SG 3.47Å; E162-F175 HydrophobicContact CG-CD2 3.75Å; E162-F175 HydrophobicContact CG-CE2 3.83Å
163F98.4Very high98Very high1 Ų152.9 Ų52.90%0.00428%0.28CS..THydrogen-bonded Turntrans-64.3-29.5-170.9-74.62.8000114F66 L159 V160 S165 I166 K167 K224 F225 L228F66-F163 AromaticContact CD1-CE1 3.98Å; F66-F163 HydrophobicContact CD1-CE1 3.98Å; F66-F163 HydrophobicContact CD1-CZ 4Å; F66-F163 HydrophobicContact CD2-CE1 4.42Å; F66-F163 AromaticContact CE1-CE1 3.81Å; F66-F163 HydrophobicContact CE1-CE1 3.81Å; F66-F163 HydrophobicContact CE1-CE2 4.49Å; F66-F163 AromaticContact CE1-CZ 3.48Å; F66-F163 HydrophobicContact CE1-CZ 3.48Å; F66-F163 VanDerWaalsContact CE1-CZ 3.48Å; F66-F163 HydrophobicContact CE2-CE1 4.26Å; F66-F163 HydrophobicContact CG-CE1 4.27Å; F66-F163 AromaticContact CZ-CE1 3.94Å; F66-F163 HydrophobicContact CZ-CE1 3.94Å; F66-F163 AromaticContact CZ-CZ 3.77Å; F66-F163 HydrophobicContact CZ-CZ 3.77Å; L159-F163 HydrophobicContact CB-CE1 4.37Å; L159-F163 WeakPolarHBondContact O-CD1 3.14Å; L159-F163 VanDerWaalsContact O-CE1 3.32Å; L159-F163 WeakPolarHBondContact O-CE1 3.46Å; V160-F163 HydrophobicContact CG2-CE2 4.32Å; V160-F163 WeakPolarHBondContact O-CB 3.38Å; V160-F163 PolarHBondContact O-N 3.13Å; F163-S165 VanDerWaalsContact C-N 3.3Å; F163-I166 HydrophobicContact CD1-CD1 4.25Å; F163-I166 HydrophobicContact CD1-CG1 4.5Å; F163-I166 CarbonylContact O-C 3.5Å; F163-I166 PolarHBondContact O-N 3.29Å; F163-K167 WeakPolarHBondContact O-CA 3.29Å; F163-K167 PolarHBondContact O-N 3.01Å; F163-K167 VanDerWaalsContact O-N 3.08Å; F163-K224 HydrophobicContact CD2-CB 3.98Å; F163-K224 WeakPolarHBondContact CD2-O 3.38Å; F163-K224 HydrophobicContact CE2-CB 4.35Å; F163-F225 HydrophobicContact CE2-CB 4.29Å; F163-F225 HydrophobicContact CE2-CD1 4.47Å; F163-F225 AromaticContact CE2-CD2 3.44Å; F163-F225 HydrophobicContact CE2-CD2 3.44Å; F163-F225 VanDerWaalsContact CE2-CD2 3.44Å; F163-F225 AromaticContact CE2-CE2 3.79Å; F163-F225 HydrophobicContact CE2-CE2 3.79Å; F163-F225 AromaticContact CE2-CG 3.82Å; F163-F225 HydrophobicContact CE2-CG 3.82Å; F163-F225 HydrophobicContact CE2-CZ 4.45Å; F163-F225 HydrophobicContact CZ-CD1 4.39Å; F163-F225 AromaticContact CZ-CD2 3.87Å; F163-F225 HydrophobicContact CZ-CD2 3.87Å; F163-F225 HydrophobicContact CZ-CE1 4.33Å; F163-F225 AromaticContact CZ-CE2 3.8Å; F163-F225 HydrophobicContact CZ-CE2 3.8Å; F163-F225 HydrophobicContact CZ-CG 4.16Å; F163-F225 HydrophobicContact CZ-CZ 4.04Å; F163-L228 HydrophobicContact CB-CD2 3.93Å; F163-L228 HydrophobicContact CD1-CD1 4.46Å; F163-L228 HydrophobicContact CD1-CD2 4.48Å; F163-L228 HydrophobicContact CD2-CD1 4.42Å; F163-L228 HydrophobicContact CD2-CG 4.36Å; F163-L228 HydrophobicContact CE1-CD1 4.48Å; F163-L228 HydrophobicContact CE2-CD1 4.47Å; F163-L228 HydrophobicContact CG-CD1 4.43Å; F163-L228 HydrophobicContact CG-CD2 4.1Å; F163-L228 HydrophobicContact CG-CG 4.36Å; F163-L228 HydrophobicContact CZ-CD1 4.49Å
164D97.9Very high98Very high114 Ų11456.8 Ų56.861%0.6131%0.309SS*.THydrogen-bonded Turntrans-67.9-33.4174.3-70.4-24.6000111.3E162 I166E162-D164 VanDerWaalsContact C-N 3.27Å; E162-D164 PolarHBondContact O-N 2.85Å; D164-I166 VanDerWaalsContact C-N 3.34Å
165S98.3Very high97.9Very high69 Ų6952.7 Ų52.748%0.48328%0.282SS..THydrogen-bonded Turntrans-72.6-26.4176.6-58.20000112.9E162 F163E162-S165 WeakPolarHBondContact O-CA 3.27Å; E162-S165 VanDerWaalsContact O-CB 3.31Å; E162-S165 WeakPolarHBondContact O-CB 3.41Å; E162-S165 PolarHBondContact O-N 3.44Å; F163-S165 VanDerWaalsContact C-N 3.3Å
166I98.6Very high97.8Very high0 Ų052 Ų520%028%0.284CS..THydrogen-bonded Turntrans-116.129.2-179.161.2142.7000113.5I59 N61 F66 E162 F163 D164 T168 S171 L228I59-I166 HydrophobicContact CD1-CD1 3.71Å; I59-I166 HydrophobicContact CD1-CG1 4.48Å; I59-I166 HydrophobicContact CG1-CD1 3.83Å; I59-I166 HydrophobicContact CG2-CG2 4.09Å; N61-I166 HydrophobicContact CB-CB 4.24Å; N61-I166 HydrophobicContact CB-CD1 4.38Å; N61-I166 WeakPolarHBondContact CB-O 3.45Å; N61-I166 PolarHBondContact ND2-O 3.15Å; N61-I166 VanDerWaalsContact ND2-O 3.11Å; F66-I166 HydrophobicContact CB-CD1 3.55Å; F66-I166 HydrophobicContact CG-CD1 4.33Å; E162-I166 WeakPolarHBondContact O-CG1 3.04Å; E162-I166 PolarHBondContact O-N 2.95Å; F163-I166 HydrophobicContact CD1-CD1 4.25Å; F163-I166 HydrophobicContact CD1-CG1 4.5Å; F163-I166 CarbonylContact O-C 3.5Å; F163-I166 PolarHBondContact O-N 3.29Å; D164-I166 VanDerWaalsContact C-N 3.34Å; I166-T168 VanDerWaalsContact C-N 3.34Å; I166-T168 PolarHBondContact O-N 3.03Å; I166-S171 WeakPolarHBondContact CA-OG 3.13Å; I166-S171 PolarHBondContact O-OG 3.26Å; I166-L228 HydrophobicContact CD1-CD2 4.27Å; I166-L228 HydrophobicContact CG1-CD2 4.28Å
167K98.5Very high97.7Very high80 Ų8057.3 Ų57.335%0.34831%0.313SS..  trans-59.1-40.7-169.6-173.5177.3178.6-166.70113.6N61 F163 L229 E237N61-K167 PolarHBondContact ND2-O 2.97Å; N61-K167 VanDerWaalsContact ND2-O 3.15Å; F163-K167 WeakPolarHBondContact O-CA 3.29Å; F163-K167 PolarHBondContact O-N 3.01Å; F163-K167 VanDerWaalsContact O-N 3.08Å; K167-L229 HydrophobicContact CG-CD1 4.42Å; K167-L229 HydrophobicContact CG-CG 4.27Å; K167-L229 PolarHBondContact O-N 3.47Å; K167-E237 IonicContact NZ-OE1 3.92Å
168T98.6Very high97.7Very high31 Ų3154.9 Ų54.919%0.1930%0.302CS..SBendtrans-105.2159.4-17451.60000112.3N61 I166 D170 S171 L229 S231N61-T168 WeakPolarHBondContact CB-O 3.49Å; N61-T168 VanDerWaalsContact ND2-C 3.32Å; N61-T168 PolarHBondContact ND2-O 3.46Å; I166-T168 VanDerWaalsContact C-N 3.34Å; I166-T168 PolarHBondContact O-N 3.03Å; T168-D170 PolarHBondContact O-N 3.01Å; T168-S171 PolarHBondContact N-OG 3.18Å; T168-S171 WeakPolarHBondContact O-CB 3.47Å; T168-S171 PolarHBondContact O-N 3.48Å; T168-S171 PolarHBondContact O-OG 2.81Å; T168-L229 HydrophobicContact CG2-CD1 3.99Å; T168-S231 WeakPolarHBondContact CB-O 3.41Å
169K98.4Very high97.8Very high75 Ų7553.2 Ų53.233%0.32630%0.296SS..BIsolated β-bridgetrans-51.4142.6171.6173.1-178.7176-1720112S171 F230 S231K169-S171 PolarHBondContact O-N 2.92Å; K169-F230 WeakPolarHBondContact CB-O 3.37Å; K169-S231 PolarHBondContact N-O 3.34Å
170D98Very high97.7Very high111 Ų11153.2 Ų53.259%0.59430%0.296SS*.THydrogen-bonded Turntrans66.54.9-179.9-54.4-37.9000114.7N61 T168N61-D170 WeakPolarHBondContact O-CA 3.24Å; N61-D170 PolarHBondContact O-N 3.14Å; T168-D170 PolarHBondContact O-N 3.01Å
171S98.3Very high97.6Very high25 Ų2557.3 Ų57.318%0.17532%0.315CS..  trans-81.6137.5170.164.40000111.3N61 I166 T168 K169N61-S171 PolarHBondContact N-O 2.55Å; I166-S171 WeakPolarHBondContact CA-OG 3.13Å; I166-S171 PolarHBondContact O-OG 3.26Å; T168-S171 PolarHBondContact N-OG 3.18Å; T168-S171 WeakPolarHBondContact O-CB 3.47Å; T168-S171 PolarHBondContact O-N 3.48Å; T168-S171 PolarHBondContact O-OG 2.81Å; K169-S171 PolarHBondContact O-N 2.92Å
172Q98.3Very high97.6Very high113 Ų11355.8 Ų55.853%0.52831%0.305SS..EExtended strand (participates in β ladder)trans-144.5150.9-176.960.1177.760.200111.4E58 I59 L60E58-Q172 PolarHBondContact OE2-NE2 3.09Å; I59-Q172 VanDerWaalsContact O-CA 3.26Å; I59-Q172 WeakPolarHBondContact O-CA 3.48Å; L60-Q172 HydrophobicContact CB-CB 4.13Å; L60-Q172 HydrophobicContact CD1-CB 3.88Å
173C98Very high97.6Very high29 Ų2953.2 Ų53.220%0.19629%0.293CS..EExtended strand (participates in β ladder)trans-137.9161.2169.5640000111.2E58 I59 E162 F175E58-C173 WeakPolarHBondContact CA-O 3.34Å; E58-C173 WeakPolarHBondContact CB-O 3.24Å; I59-C173 WeakPolarHBondContact CG2-SG 3.4Å; I59-C173 PolarHBondContact N-O 3.35Å; I59-C173 PolarHBondContact O-N 3.48Å; E162-C173 PolarHBondContact OE2-SG 3.47Å; C173-F175 PolarHBondContact O-N 2.95Å
174S97.7Very high97.6Very high98 Ų9854.3 Ų54.369%0.68530%0.299SS*.EExtended strand (participates in β ladder)trans-63.4133.9172.6-176.80000109.7
175F97.5Very high97.6Very high3 Ų349.4 Ų49.41%0.01327%0.273CS..  trans-141.688.4-179.6-168.7-108.1000108.8C56 L57 I59 V68 K158 L159 E162 C173 F178C56-F175 CarbonylContact C-O 3.57Å; C56-F175 PolarHBondContact SG-O 3.16Å; L57-F175 CarbonylContact C-O 3.44Å; L57-F175 PolarHBondContact N-O 2.96Å; L57-F175 PolarHBondContact O-N 3.37Å; I59-F175 HydrophobicContact CB-CB 3.95Å; I59-F175 HydrophobicContact CB-CG 4.19Å; I59-F175 HydrophobicContact CG2-CB 3.86Å; I59-F175 HydrophobicContact CG2-CD2 4.35Å; I59-F175 HydrophobicContact CG2-CG 4.21Å; V68-F175 HydrophobicContact CG1-CD1 3.77Å; V68-F175 HydrophobicContact CG1-CE1 4.17Å; V68-F175 HydrophobicContact CG2-CD1 4.19Å; V68-F175 HydrophobicContact CG2-CE1 4.25Å; K158-F175 HydrophobicContact CD-CE2 4.37Å; K158-F175 HydrophobicContact CD-CZ 4.3Å; K158-F175 HydrophobicContact CG-CE2 3.73Å; K158-F175 HydrophobicContact CG-CZ 3.82Å; K158-F175 WeakPolarHBondContact O-CE2 3.22Å; L159-F175 HydrophobicContact CD2-CE1 3.58Å; L159-F175 HydrophobicContact CD2-CE2 4.35Å; L159-F175 HydrophobicContact CD2-CZ 3.46Å; L159-F175 VanDerWaalsContact CD2-CZ 3.46Å; L159-F175 HydrophobicContact CG-CZ 4.18Å; E162-F175 HydrophobicContact CG-CD2 3.75Å; E162-F175 HydrophobicContact CG-CE2 3.83Å; C173-F175 PolarHBondContact O-N 2.95Å; F175-F178 HydrophobicContact CD1-CB 4.2Å; F175-F178 HydrophobicContact CE1-CB 3.56Å; F175-F178 HydrophobicContact CE1-CD1 4.17Å; F175-F178 AromaticContact CE1-CD2 3.66Å; F175-F178 HydrophobicContact CE1-CD2 3.66Å; F175-F178 HydrophobicContact CE1-CE2 4.41Å; F175-F178 AromaticContact CE1-CG 3.52Å; F175-F178 HydrophobicContact CE1-CG 3.52Å; F175-F178 HydrophobicContact CZ-CB 4.2Å; F175-F178 AromaticContact CZ-CD2 3.59Å; F175-F178 HydrophobicContact CZ-CD2 3.59Å; F175-F178 HydrophobicContact CZ-CE2 4.18Å; F175-F178 AromaticContact CZ-CG 3.97Å; F175-F178 HydrophobicContact CZ-CG 3.97Å
176A94.2Very high97.4Very high45 Ų4550.1 Ų50.137%0.37229%0.292SS..  trans-102.8165.2-175.300000112.2K158 F178K158-A176 PolarHBondContact NZ-O 2.9Å; A176-F178 PolarHBondContact O-N 2.88Å
177D95.3Very high97.3Very high112 Ų11252.6 Ų52.660%0.59931%0.308SS*.SBendtrans55.252.7171.7-58.7-45.1000113.2P53 K158P53-D177 VanDerWaalsContact O-CA 3.3Å; P53-D177 WeakPolarHBondContact O-CA 3.36Å; P53-D177 PolarHBondContact O-N 3.31Å; K158-D177 PolarHBondContact NZ-O 2.81Å
178F97.6Very high97.3Very high2 Ų251.4 Ų51.41%0.00931%0.305CS..  trans-118.9124.1176.5-172.4-92.6000110.2P53 C56 F93 K158 L159 F175 A176 P180 M182 L183P53-F178 WeakPolarHBondContact CA-O 3.09Å; P53-F178 PolarHBondContact O-N 2.85Å; C56-F178 HydrophobicContact CB-CB 4.17Å; F93-F178 AromaticContact CE1-CD1 3.88Å; F93-F178 HydrophobicContact CE1-CD1 3.88Å; F93-F178 AromaticContact CE1-CE1 3.72Å; F93-F178 HydrophobicContact CE1-CE1 3.72Å; F93-F178 HydrophobicContact CZ-CD1 4.06Å; F93-F178 AromaticContact CZ-CE1 3.65Å; F93-F178 HydrophobicContact CZ-CE1 3.65Å; F93-F178 HydrophobicContact CZ-CZ 4.4Å; K158-F178 HydrophobicContact CB-CE2 4.41Å; K158-F178 HydrophobicContact CD-CD2 4.02Å; K158-F178 HydrophobicContact CG-CD2 4.37Å; L159-F178 HydrophobicContact CD1-CZ 4.11Å; L159-F178 HydrophobicContact CG-CE2 4.22Å; L159-F178 HydrophobicContact CG-CZ 4.17Å; F175-F178 HydrophobicContact CD1-CB 4.2Å; F175-F178 HydrophobicContact CE1-CB 3.56Å; F175-F178 HydrophobicContact CE1-CD1 4.17Å; F175-F178 AromaticContact CE1-CD2 3.66Å; F175-F178 HydrophobicContact CE1-CD2 3.66Å; F175-F178 HydrophobicContact CE1-CE2 4.41Å; F175-F178 AromaticContact CE1-CG 3.52Å; F175-F178 HydrophobicContact CE1-CG 3.52Å; F175-F178 HydrophobicContact CZ-CB 4.2Å; F175-F178 AromaticContact CZ-CD2 3.59Å; F175-F178 HydrophobicContact CZ-CD2 3.59Å; F175-F178 HydrophobicContact CZ-CE2 4.18Å; F175-F178 AromaticContact CZ-CG 3.97Å; F175-F178 HydrophobicContact CZ-CG 3.97Å; A176-F178 PolarHBondContact O-N 2.88Å; F178-P180 HydrophobicContact CE1-CB 4.47Å; F178-P180 VanDerWaalsContact O-CD 3.32Å; F178-P180 WeakPolarHBondContact O-CD 3.43Å; F178-M182 HydrophobicContact CD2-SD 4.13Å; F178-M182 HydrophobicContact CE1-SD 4.42Å; F178-M182 HydrophobicContact CE2-CG 4.47Å; F178-M182 HydrophobicContact CE2-SD 3.58Å; F178-M182 VanDerWaalsContact CE2-SD 3.58Å; F178-M182 HydrophobicContact CZ-CG 4.04Å; F178-M182 HydrophobicContact CZ-SD 3.74Å; F178-L183 HydrophobicContact CE1-CD1 3.8Å; F178-L183 HydrophobicContact CE1-CG 4.19Å; F178-L183 HydrophobicContact CZ-CD1 3.8Å; F178-L183 HydrophobicContact CZ-CD2 4.21Å; F178-L183 HydrophobicContact CZ-CG 3.97Å
179N97.4Very high97.3Very high46 Ų4652.4 Ų52.425%0.24631%0.31CS..  trans-95.4106.3176.1-171.2-8.9000110Y51 P53 E181 M182Y51-N179 WeakPolarHBondContact CB-OD1 3.07Å; P53-N179 HydrophobicContact CB-CB 4.37Å; P53-N179 HydrophobicContact CG-CB 3.8Å; N179-E181 PolarHBondContact O-N 3.08Å; N179-E181 WeakPolarHBondContact OD1-CB 3.34Å; N179-E181 PolarHBondContact OD1-N 2.81Å; N179-M182 WeakPolarHBondContact O-CG 3.22Å; N179-M182 PolarHBondContact O-N 3.38Å; N179-M182 VanDerWaalsContact O-N 3.14Å
180P97.1Very high97.3Very high0 Ų049 Ų490%030%0.295CS..G310 helixtrans-64.9-12.7179.320.7-25.8000114.5Y51 F70 L90 F93 L120 F178 M182 L183Y51-P180 HydrophobicContact CD1-CG 4.33Å; Y51-P180 HydrophobicContact CD2-CB 4.24Å; Y51-P180 HydrophobicContact CD2-CG 3.59Å; Y51-P180 HydrophobicContact CE2-CB 4.31Å; Y51-P180 HydrophobicContact CE2-CG 3.99Å; Y51-P180 HydrophobicContact CG-CG 3.75Å; F70-P180 HydrophobicContact CE1-CG 4.04Å; F70-P180 HydrophobicContact CZ-CB 4.41Å; F70-P180 HydrophobicContact CZ-CG 3.79Å; L90-P180 HydrophobicContact CD2-CG 3.62Å; F93-P180 HydrophobicContact CD1-CB 4.12Å; F93-P180 HydrophobicContact CE1-CB 4.17Å; L120-P180 HydrophobicContact CD2-CB 3.55Å; L120-P180 HydrophobicContact CD2-CG 4.33Å; F178-P180 HydrophobicContact CE1-CB 4.47Å; F178-P180 VanDerWaalsContact O-CD 3.32Å; F178-P180 WeakPolarHBondContact O-CD 3.43Å; P180-M182 PolarHBondContact O-N 2.73Å; P180-L183 WeakPolarHBondContact O-CB 3.12Å; P180-L183 PolarHBondContact O-N 2.8Å
181E96.4Very high97.4Very high96 Ų9644.2 Ų44.245%0.44927%0.269SS..G310 helixtrans-58.3-29172.8-162.6176.8175.700111.9Y51 N179 L183 L184Y51-E181 HydrophobicContact CD2-CB 3.98Å; N179-E181 PolarHBondContact O-N 3.08Å; N179-E181 WeakPolarHBondContact OD1-CB 3.34Å; N179-E181 PolarHBondContact OD1-N 2.81Å; E181-L183 PolarHBondContact O-N 2.87Å; E181-L183 VanDerWaalsContact O-N 3.15Å; E181-L184 HydrophobicContact CB-CD1 4.44Å; E181-L184 HydrophobicContact CG-CD1 3.97Å; E181-L184 WeakPolarHBondContact O-CB 3.29Å; E181-L184 PolarHBondContact O-N 2.92Å; E181-L184 VanDerWaalsContact O-N 3.08Å
182M96.4Very high97.4Very high68 Ų6843 Ų4334%0.33526%0.26SS..G310 helixtrans-66.7-13.2177.175.6-166.6-48.800113.7N155 F178 N179 P180N155-M182 HydrophobicContact CB-CB 4.03Å; N155-M182 HydrophobicContact CB-CE 3.79Å; N155-M182 HydrophobicContact CB-CG 3.86Å; N155-M182 VanDerWaalsContact CB-O 3.3Å; N155-M182 WeakPolarHBondContact CB-O 3.26Å; N155-M182 HydrophobicContact CB-SD 4.48Å; N155-M182 PolarHBondContact ND2-O 2.83Å; N155-M182 WeakPolarHBondContact OD1-CE 3.38Å; F178-M182 HydrophobicContact CD2-SD 4.13Å; F178-M182 HydrophobicContact CE1-SD 4.42Å; F178-M182 HydrophobicContact CE2-CG 4.47Å; F178-M182 HydrophobicContact CE2-SD 3.58Å; F178-M182 VanDerWaalsContact CE2-SD 3.58Å; F178-M182 HydrophobicContact CZ-CG 4.04Å; F178-M182 HydrophobicContact CZ-SD 3.74Å; N179-M182 WeakPolarHBondContact O-CG 3.22Å; N179-M182 PolarHBondContact O-N 3.38Å; N179-M182 VanDerWaalsContact O-N 3.14Å; P180-M182 PolarHBondContact O-N 2.73Å
183L98.1Very high97.4Very high0 Ų037.9 Ų37.90%024%0.236CC..G310 helixtrans-98.57.3176.8-55.3-178.2000112.7F93 F95 L118 N155 L156 L159 F178 P180 E181F93-L183 HydrophobicContact CE2-CD1 4.24Å; F93-L183 HydrophobicContact CZ-CD1 4.12Å; F95-L183 HydrophobicContact CZ-CD1 4.21Å; L118-L183 HydrophobicContact CD2-CB 3.63Å; L118-L183 HydrophobicContact CD2-CD1 4.16Å; N155-L183 HydrophobicContact CB-CD2 4.15Å; L156-L183 HydrophobicContact CD2-CD2 3.58Å; L156-L183 HydrophobicContact CG-CD2 4.14Å; L159-L183 HydrophobicContact CD1-CD1 4.06Å; F178-L183 HydrophobicContact CE1-CD1 3.8Å; F178-L183 HydrophobicContact CE1-CG 4.19Å; F178-L183 HydrophobicContact CZ-CD1 3.8Å; F178-L183 HydrophobicContact CZ-CD2 4.21Å; F178-L183 HydrophobicContact CZ-CG 3.97Å; P180-L183 WeakPolarHBondContact O-CB 3.12Å; P180-L183 PolarHBondContact O-N 2.8Å; E181-L183 PolarHBondContact O-N 2.87Å; E181-L183 VanDerWaalsContact O-N 3.15Å
184L98.3Very high97.5Very high23 Ų2339.6 Ų39.612%0.1224%0.241CC..SBendtrans-91150.3175.5-60.6175000111.1L49 L120 V143 V145 E181 L188L49-L184 HydrophobicContact CD1-CD1 3.42Å; L49-L184 VanDerWaalsContact CD1-CD1 3.42Å; L49-L184 HydrophobicContact CD1-CD2 4.29Å; L120-L184 HydrophobicContact CD1-CD2 3.64Å; V143-L184 HydrophobicContact CG1-CD2 4.28Å; V145-L184 HydrophobicContact CG2-CD2 4.12Å; E181-L184 HydrophobicContact CB-CD1 4.44Å; E181-L184 HydrophobicContact CG-CD1 3.97Å; E181-L184 WeakPolarHBondContact O-CB 3.29Å; E181-L184 PolarHBondContact O-N 2.92Å; E181-L184 VanDerWaalsContact O-N 3.08Å; L184-L188 HydrophobicContact CB-CD2 4.14Å; L184-L188 HydrophobicContact CD1-CD2 4.38Å
185P97.8Very high97.5Very high11 Ų1135 Ų357%0.07121%0.209CC..  trans-68.7163.1171.130.9-35.6000111.6C187 L188 C211 E213 I215P185-C187 VanDerWaalsContact C-N 3.33Å; P185-C187 WeakPolarHBondContact CG-O 3.46Å; P185-C187 PolarHBondContact O-N 3Å; P185-L188 HydrophobicContact CG-CD2 4.27Å; P185-C211 HydrophobicContact CG-CB 3.96Å; P185-E213 HydrophobicContact CB-CB 3.77Å; P185-E213 HydrophobicContact CB-CG 3.81Å; P185-E213 WeakPolarHBondContact CB-O 3.44Å; P185-E213 HydrophobicContact CG-CB 4.32Å; P185-E213 WeakPolarHBondContact CG-O 3.18Å; P185-I215 HydrophobicContact CB-CG2 4.22Å
186G95.8Very high97.6Very high84 Ų8434.8 Ų34.887%0.86621%0.208SC*.SBendtrans-65.2-35.9177.800000113
187C96.8Very high97.8Very high52 Ų5234.2 Ų34.235%0.35120%0.199SC..  trans-103.5122.9172.3-175.40000111.1P185 D189 E213P185-C187 VanDerWaalsContact C-N 3.33Å; P185-C187 WeakPolarHBondContact CG-O 3.46Å; P185-C187 PolarHBondContact O-N 3Å; C187-D189 VanDerWaalsContact C-N 3.28Å; C187-D189 PolarHBondContact O-N 3.15Å; C187-D189 VanDerWaalsContact SG-CG 3.53Å; C187-E213 WeakPolarHBondContact CB-OE2 3.4Å; C187-E213 PolarHBondContact N-OE2 2.95Å
188L97.6Very high97.9Very high55 Ų5529.1 Ų29.129%0.28817%0.171SC..  trans-91.829.2176.7-63.2-178.7000112.9L47 L49 L184 P185 Y190L47-L188 HydrophobicContact CB-CD1 4.48Å; L47-L188 HydrophobicContact CD1-CB 4.42Å; L49-L188 HydrophobicContact CD1-CD1 4.24Å; L184-L188 HydrophobicContact CB-CD2 4.14Å; L184-L188 HydrophobicContact CD1-CD2 4.38Å; P185-L188 HydrophobicContact CG-CD2 4.27Å; L188-Y190 VanDerWaalsContact O-CD1 3.3Å; L188-Y190 WeakPolarHBondContact O-CD1 3.37Å
189D98.5Very high98Very high53 Ų5330.6 Ų30.628%0.28318%0.181SC..  trans-60.5135.3166.3-86.5-5000109.4C187 K212 F259C187-D189 VanDerWaalsContact C-N 3.28Å; C187-D189 PolarHBondContact O-N 3.15Å; C187-D189 VanDerWaalsContact SG-CG 3.53Å; D189-K212 HydrophobicContact CB-CB 4.15Å; D189-K212 HydrophobicContact CB-CD 4.15Å; D189-K212 WeakPolarHBondContact O-CB 3.35Å; D189-K212 PolarHBondContact O-N 2.84Å; D189-F259 HydrophobicContact CB-CB 4.34Å; D189-F259 HydrophobicContact CB-CD1 3.65Å; D189-F259 HydrophobicContact CB-CE1 4.29Å; D189-F259 HydrophobicContact CB-CG 4.19Å; D189-F259 WeakPolarHBondContact OD2-CB 3.18Å
190Y98.8Very high97.9Very high2 Ų229 Ų291%0.00817%0.173CC..EExtended strand (participates in β ladder)trans-142.2155.5-172.364.6-88.8000113.7L44 K45 L47 G82 P83 L188 T192 I209 V210 S258L44-Y190 WeakPolarHBondContact CB-OH 3.26Å; L44-Y190 HydrophobicContact CD1-CE2 4.1Å; L44-Y190 HydrophobicContact CD2-CE2 4.29Å; K45-Y190 PolarHBondContact O-OH 3.2Å; L47-Y190 HydrophobicContact CD1-CD1 3.79Å; L47-Y190 HydrophobicContact CD1-CE1 4.23Å; L47-Y190 HydrophobicContact CD1-CG 4.31Å; L47-Y190 HydrophobicContact CD2-CD1 4.32Å; L47-Y190 HydrophobicContact CD2-CE1 4.02Å; L47-Y190 HydrophobicContact CG-CD1 3.81Å; L47-Y190 HydrophobicContact CG-CE1 3.72Å; G82-Y190 WeakPolarHBondContact CA-OH 3.23Å; P83-Y190 HydrophobicContact CG-CE2 4.22Å; L188-Y190 VanDerWaalsContact O-CD1 3.3Å; L188-Y190 WeakPolarHBondContact O-CD1 3.37Å; Y190-T192 HydrophobicContact CD2-CG2 4.4Å; Y190-T192 HydrophobicContact CE2-CG2 4.04Å; Y190-I209 HydrophobicContact CD1-CG2 4.46Å; Y190-I209 HydrophobicContact CD2-CG2 3.9Å; Y190-I209 HydrophobicContact CG-CG2 3.82Å; Y190-V210 CarbonylContact C-O 3.56Å; Y190-V210 VanDerWaalsContact CA-O 3.3Å; Y190-V210 WeakPolarHBondContact CA-O 3.46Å; Y190-S258 PolarHBondContact N-OG 2.92Å; Y190-S258 PolarHBondContact O-N 2.79Å; Y190-S258 PolarHBondContact O-OG 2.94Å
191W98.9Very high97.9Very high12 Ų1232 Ų325%0.04519%0.192CC..EExtended strand (participates in β ladder)trans-95.7151.2158.7-63.1-76.1000110.4I33 P35 V109 I209 V210 K212 V255 R256 F259I33-W191 HydrophobicContact CD1-CB 4.21Å; I33-W191 HydrophobicContact CD1-CD2 4.32Å; I33-W191 HydrophobicContact CD1-CE3 4.05Å; I33-W191 HydrophobicContact CD1-CG 4.42Å; I33-W191 HydrophobicContact CG2-CD2 3.75Å; I33-W191 HydrophobicContact CG2-CE3 4.28Å; I33-W191 HydrophobicContact CG2-CG 3.85Å; I33-W191 HydrophobicContact CG2-CZ2 4.36Å; P35-W191 HydrophobicContact CB-CZ2 4.34Å; P35-W191 HydrophobicContact CG-CZ2 4Å; V109-W191 HydrophobicContact CG1-CH2 4Å; V109-W191 HydrophobicContact CG1-CZ2 4.46Å; V109-W191 HydrophobicContact CG2-CH2 4.17Å; V109-W191 HydrophobicContact CG2-CZ3 4.04Å; W191-I209 CarbonylContact O-C 3.51Å; W191-I209 WeakPolarHBondContact O-CA 2.88Å; W191-V210 PolarHBondContact N-O 3.38Å; W191-V210 PolarHBondContact O-N 2.83Å; W191-K212 HydrophobicContact CH2-CB 4.15Å; W191-K212 HydrophobicContact CH2-CG 3.82Å; W191-K212 HydrophobicContact CZ2-CG 4.31Å; W191-K212 HydrophobicContact CZ3-CB 4.04Å; W191-K212 HydrophobicContact CZ3-CG 4.22Å; W191-V255 HydrophobicContact CB-CG1 3.78Å; W191-V255 HydrophobicContact CG-CG1 4.12Å; W191-R256 CarbonylContact C-O 3.34Å; W191-R256 VanDerWaalsContact CA-O 3.23Å; W191-R256 WeakPolarHBondContact CA-O 3.3Å; W191-F259 HydrophobicContact CD2-CE1 4.36Å; W191-F259 HydrophobicContact CD2-CZ 4.23Å; W191-F259 AromaticContact CE2-CZ 3.5Å; W191-F259 VanDerWaalsContact CE2-CZ 3.5Å; W191-F259 HydrophobicContact CH2-CZ 4.43Å; W191-F259 HydrophobicContact CZ2-CE1 4.44Å; W191-F259 AromaticContact CZ2-CZ 3.61Å; W191-F259 HydrophobicContact CZ2-CZ 3.61Å; W191-F259 AromaticContact NE1-CZ 3.49Å
192T98.9Very high98Very high0 Ų027.4 Ų27.40%017%0.171CC..EExtended strand (participates in β ladder)trans-141.1143.3175.8-1770000113L44 P83 Y190 W208 R256L44-T192 HydrophobicContact CD1-CG2 3.75Å; L44-T192 HydrophobicContact CD2-CG2 3.96Å; P83-T192 HydrophobicContact CB-CG2 3.98Å; P83-T192 WeakPolarHBondContact CB-OG1 3.39Å; P83-T192 HydrophobicContact CG-CG2 4.34Å; P83-T192 WeakPolarHBondContact CG-OG1 3.37Å; Y190-T192 HydrophobicContact CD2-CG2 4.4Å; Y190-T192 HydrophobicContact CE2-CG2 4.04Å; T192-W208 WeakPolarHBondContact CA-O 3.32Å; T192-W208 VanDerWaalsContact CB-O 3.22Å; T192-W208 WeakPolarHBondContact CB-O 3.3Å; T192-W208 PolarHBondContact OG1-O 3.4Å; T192-R256 HydrophobicContact CG2-CB 3.91Å; T192-R256 PolarHBondContact N-O 2.77Å; T192-R256 PolarHBondContact O-N 3.11Å
193Y98.9Very high98.1Very high4 Ų426.8 Ų26.82%0.01617%0.169CC..EExtended strand (participates in β ladder)trans-158.8160.2176.175.1-80.4000111S29 I31 H107 W208S29-Y193 WeakPolarHBondContact CB-OH 3.39Å; S29-Y193 WeakPolarHBondContact OG-CE2 3.3Å; S29-Y193 PolarHBondContact OG-OH 3.14Å; I31-Y193 HydrophobicContact CD1-CD1 3.73Å; I31-Y193 HydrophobicContact CD1-CD2 3.88Å; I31-Y193 HydrophobicContact CD1-CE1 3.72Å; I31-Y193 HydrophobicContact CD1-CE2 3.88Å; I31-Y193 HydrophobicContact CD1-CG 3.82Å; I31-Y193 HydrophobicContact CG1-CD1 4.33Å; I31-Y193 HydrophobicContact CG1-CE1 3.79Å; I31-Y193 HydrophobicContact CG1-CE2 4.07Å; I31-Y193 HydrophobicContact CG2-CE2 4.15Å; H107-Y193 AromaticContact NE2-CE1 3.48Å; H107-Y193 WeakPolarHBondContact NE2-CE1 3.41Å; H107-Y193 AromaticContact NE2-CZ 3.47Å; H107-Y193 PolarHBondContact NE2-OH 3.06Å; Y193-W208 HydrophobicContact CD1-CB 3.67Å; Y193-W208 HydrophobicContact CD1-CG 4.36Å; Y193-W208 HydrophobicContact CE1-CB 3.36Å; Y193-W208 AromaticContact CE1-CD1 3.99Å; Y193-W208 HydrophobicContact CE1-CD2 4.45Å; Y193-W208 AromaticContact CE1-CG 3.62Å; Y193-W208 HydrophobicContact CE1-CG 3.62Å; Y193-W208 AromaticContact CE2-CD1 3.9Å; Y193-W208 HydrophobicContact CE2-CG 4.35Å; Y193-W208 HydrophobicContact CG-CB 4.38Å; Y193-W208 AromaticContact CZ-CD1 3.5Å; Y193-W208 AromaticContact CZ-CG 3.61Å; Y193-W208 PolarHBondContact N-O 3.18Å; Y193-W208 PolarHBondContact O-N 2.84Å
194E98.7Very high98.1Very high65 Ų6528 Ų2830%0.30418%0.175SC..EExtended strand (participates in β ladder)trans-85.3127.3173.7-59.1-56.4153.800111.1T207 R253E194-T207 PolarHBondContact OE1-OG1 3.5Å; E194-T207 PolarHBondContact OE2-OG1 2.89Å; E194-R253 WeakPolarHBondContact O-CD 3.15Å; E194-R253 PolarHBondContact O-NH1 3.38Å; E194-R253 VanDerWaalsContact O-NH1 3.14Å
195G98.8Very high98.1Very high1 Ų127 Ų271%0.0117%0.169CC..EExtended strand (participates in β ladder)trans-144.3-156.9-169.200000114.1R27 S29 E204 S205 V206R27-G195 CarbonylContact O-C 3.55Å; R27-G195 WeakPolarHBondContact O-CA 3.41Å; S29-G195 VanDerWaalsContact OG-CA 3.29Å; S29-G195 WeakPolarHBondContact OG-CA 3.14Å; G195-E204 CarbonylContact O-C 3.46Å; G195-E204 WeakPolarHBondContact O-CA 3.46Å; G195-S205 PolarHBondContact O-N 2.79Å; G195-V206 CarbonylContact C-O 3.55Å; G195-V206 WeakPolarHBondContact CA-O 3.22Å; G195-V206 PolarHBondContact N-O 2.86Å; G195-V206 PolarHBondContact O-N 2.75Å
196S98.9Very high98.2Very high0 Ų026.5 Ų26.50%017%0.166CC..  trans-127.1171.2178.873.30000112.2R27 Q28 S29 L203 V206 W208R27-S196 PolarHBondContact O-N 3.31Å; Q28-S196 WeakPolarHBondContact CA-OG 3.42Å; Q28-S196 PolarHBondContact NE2-OG 3.3Å; S29-S196 WeakPolarHBondContact CB-O 3.47Å; S29-S196 PolarHBondContact N-OG 3Å; S29-S196 PolarHBondContact OG-N 2.72Å; S196-L203 CarbonylContact C-O 3.55Å; S196-L203 WeakPolarHBondContact CA-O 3.37Å; S196-L203 VanDerWaalsContact CB-O 3.24Å; S196-L203 WeakPolarHBondContact CB-O 3.32Å; S196-V206 VanDerWaalsContact C-CG2 3.42Å; S196-W208 PolarHBondContact O-NE1 3.37Å; S196-W208 VanDerWaalsContact O-NE1 3.07Å
197L98.7Very high98.3Very high33 Ų3322.9 Ų22.917%0.17313%0.127CC..  trans-56.7143153.5-63.1174.6000109.1L140 T199 L203 V206L140-L197 HydrophobicContact CD1-CD2 3.77Å; L140-L197 HydrophobicContact CD1-CG 4.37Å; L197-T199 VanDerWaalsContact C-N 3.33Å; L197-L203 HydrophobicContact CD1-CB 4.28Å; L197-L203 PolarHBondContact N-O 3.03Å; L197-V206 HydrophobicContact CD2-CG2 3.99Å; L197-V206 HydrophobicContact CG-CG2 4.26Å
198T98.6Very high98.4Very high4 Ų420.5 Ų20.53%0.02511%0.111CC..SBendtrans-90.3-3.417759.60000112.9W16 P30 E106 W208 R245W16-T198 WeakPolarHBondContact CZ3-O 3.42Å; P30-T198 HydrophobicContact CB-CG2 4.45Å; E106-T198 VanDerWaalsContact CD-CB 3.49Å; E106-T198 WeakPolarHBondContact OE1-CB 3.2Å; E106-T198 PolarHBondContact OE1-OG1 2.99Å; E106-T198 WeakPolarHBondContact OE2-CB 3.28Å; E106-T198 WeakPolarHBondContact OE2-CG2 3.45Å; E106-T198 PolarHBondContact OE2-OG1 3.1Å; T198-W208 HydrophobicContact CG2-CH2 4.34Å; T198-W208 HydrophobicContact CG2-CZ2 3.81Å; T198-R245 WeakPolarHBondContact O-CD 3.28Å
199T97.8Very high98.5Very high33 Ų3317.9 Ų17.920%0.20210%0.097CC..SBendtrans-120.6151.6173.756.40000111.2W5 Y7 L197 L202W5-T199 HydrophobicContact CH2-CG2 3.66Å; W5-T199 HydrophobicContact CZ3-CG2 4.13Å; Y7-T199 WeakPolarHBondContact OH-CG2 3.48Å; L197-T199 VanDerWaalsContact C-N 3.33Å; T199-L202 WeakPolarHBondContact O-CA 3.01Å; T199-L202 WeakPolarHBondContact O-CD2 3.34Å; T199-L202 PolarHBondContact O-N 3.04Å
200P97.2Very high98.5Very high13 Ų1315.4 Ų15.48%0.0848%0.083CC..THydrogen-bonded Turntrans-48.1131.3170.8-31.539.6000113W5 W16 F20 L202W5-P200 HydrophobicContact CB-CG 4.06Å; W5-P200 HydrophobicContact CD2-CB 4Å; W5-P200 HydrophobicContact CD2-CG 3.55Å; W5-P200 HydrophobicContact CE3-CG 3.92Å; W5-P200 HydrophobicContact CG-CB 3.9Å; W5-P200 HydrophobicContact CG-CG 3.6Å; W16-P200 HydrophobicContact CB-CG 4.5Å; W16-P200 HydrophobicContact CD2-CG 3.69Å; W16-P200 HydrophobicContact CE3-CG 3.96Å; W16-P200 HydrophobicContact CG-CG 3.97Å; W16-P200 HydrophobicContact CZ3-CG 4.45Å; F20-P200 HydrophobicContact CD1-CB 4.28Å; F20-P200 HydrophobicContact CD2-CB 3.79Å; F20-P200 HydrophobicContact CD2-CG 4.01Å; F20-P200 HydrophobicContact CE1-CB 4.03Å; F20-P200 HydrophobicContact CE2-CB 3.53Å; F20-P200 HydrophobicContact CE2-CG 3.98Å; F20-P200 HydrophobicContact CG-CB 4.16Å; F20-P200 HydrophobicContact CZ-CB 3.65Å; P200-L202 HydrophobicContact CG-CG 4.39Å
201P96.9Very high98.5Very high62 Ų6215.3 Ų15.340%0.4038%0.083SC..THydrogen-bonded Turncis-89.814.318.731.3-30.6000116.9F20 I22 L203F20-P201 HydrophobicContact CD1-CB 4.03Å; F20-P201 HydrophobicContact CE1-CB 4.12Å; I22-P201 VanDerWaalsContact CG2-O 3.22Å; I22-P201 WeakPolarHBondContact CG2-O 3.29Å; P201-L203 VanDerWaalsContact C-N 3.25Å; P201-L203 HydrophobicContact CB-CG 4.42Å; P201-L203 HydrophobicContact CG-CD1 4.04Å; P201-L203 HydrophobicContact CG-CG 3.96Å; P201-L203 PolarHBondContact O-N 3.2Å
202L98.1Very high98.5Very high0 Ų018.7 Ų18.70%010%0.098CC..  trans59.630.6171.5-53.9168.9000114.4W16 F20 I22 A23 Q28 T199 P200 E204W16-L202 HydrophobicContact CB-CD1 4.24Å; W16-L202 HydrophobicContact CE3-CD1 3.95Å; W16-L202 HydrophobicContact CE3-CD2 3.89Å; W16-L202 HydrophobicContact CE3-CG 4.4Å; W16-L202 HydrophobicContact CZ3-CD2 3.92Å; F20-L202 HydrophobicContact CB-CD1 4.37Å; I22-L202 HydrophobicContact CG2-CB 3.97Å; A23-L202 HydrophobicContact CB-CD1 3.35Å; Q28-L202 PolarHBondContact NE2-O 3.03Å; T199-L202 WeakPolarHBondContact O-CA 3.01Å; T199-L202 WeakPolarHBondContact O-CD2 3.34Å; T199-L202 PolarHBondContact O-N 3.04Å; P200-L202 HydrophobicContact CG-CG 4.39Å; L202-E204 PolarHBondContact O-N 3.37Å
203L98.1Very high98.5Very high56 Ų5622.6 Ų22.629%0.29312%0.116SC..  trans-60.2131.4-177.7-62.8172.2000110.8A134 S196 L197 P201 S205A134-L203 HydrophobicContact CB-CD1 4.44Å; A134-L203 VanDerWaalsContact O-CD1 3.26Å; A134-L203 WeakPolarHBondContact O-CD1 3.48Å; S196-L203 CarbonylContact C-O 3.55Å; S196-L203 WeakPolarHBondContact CA-O 3.37Å; S196-L203 VanDerWaalsContact CB-O 3.24Å; S196-L203 WeakPolarHBondContact CB-O 3.32Å; L197-L203 HydrophobicContact CD1-CB 4.28Å; L197-L203 PolarHBondContact N-O 3.03Å; P201-L203 VanDerWaalsContact C-N 3.25Å; P201-L203 HydrophobicContact CB-CG 4.42Å; P201-L203 HydrophobicContact CG-CD1 4.04Å; P201-L203 HydrophobicContact CG-CG 3.96Å; P201-L203 PolarHBondContact O-N 3.2Å; L203-S205 PolarHBondContact O-N 2.77Å; L203-S205 PolarHBondContact O-OG 3.33Å
204E98.6Very high98.5Very high26 Ų2623.2 Ų23.212%0.12112%0.121CC..SBendtrans-81.161.8177.3-62.8-171.7165.600111.8I22 G25 P26 R27 G195 L202I22-E204 HydrophobicContact CD1-CG 4.07Å; I22-E204 HydrophobicContact CG1-CG 4.21Å; G25-E204 VanDerWaalsContact CA-OE1 3.23Å; G25-E204 WeakPolarHBondContact CA-OE1 3.48Å; P26-E204 WeakPolarHBondContact CD-OE1 3.42Å; R27-E204 WeakPolarHBondContact CA-OE1 3.41Å; R27-E204 HydrophobicContact CB-CB 4.42Å; R27-E204 HydrophobicContact CB-CG 4.21Å; R27-E204 PolarHBondContact N-OE1 3.38Å; R27-E204 IonicContact NE-OE2 3.98Å; R27-E204 PolarHBondContact NE-OE2 3.45Å; R27-E204 PolarHBondContact NH2-O 3.46Å; R27-E204 IonicContact NH2-OE2 3.02Å; G195-E204 CarbonylContact O-C 3.46Å; G195-E204 WeakPolarHBondContact O-CA 3.46Å; L202-E204 PolarHBondContact O-N 3.37Å
205S98.4Very high98.5Very high1 Ų120.8 Ų20.81%0.00711%0.11CC..  trans-1229.1-171.949.20000114.1A134 Q136 G139 L140 G195 L203A134-S205 WeakPolarHBondContact O-CB 3.4Å; A134-S205 PolarHBondContact O-OG 3.4Å; Q136-S205 VanDerWaalsContact O-CA 3.23Å; Q136-S205 WeakPolarHBondContact O-CA 3.47Å; Q136-S205 WeakPolarHBondContact O-CB 3.28Å; G139-S205 PolarHBondContact N-O 2.94Å; L140-S205 WeakPolarHBondContact CB-O 3.48Å; L140-S205 PolarHBondContact N-O 2.85Å; G195-S205 PolarHBondContact O-N 2.79Å; L203-S205 PolarHBondContact O-N 2.77Å; L203-S205 PolarHBondContact O-OG 3.33Å
206V98.9Very high98.5Very high0 Ų022.3 Ų22.30%012%0.121CC..EExtended strand (participates in β ladder)trans-110.5120.1-167.8-1770000111.7L140 V142 G195 S196 L197 W208L140-V206 HydrophobicContact CB-CG2 4.09Å; L140-V206 HydrophobicContact CD1-CG2 4.15Å; L140-V206 WeakPolarHBondContact O-CA 3.43Å; V142-V206 HydrophobicContact CB-CG1 3.88Å; V142-V206 HydrophobicContact CG2-CG1 3.54Å; G195-V206 CarbonylContact C-O 3.55Å; G195-V206 WeakPolarHBondContact CA-O 3.22Å; G195-V206 PolarHBondContact N-O 2.86Å; G195-V206 PolarHBondContact O-N 2.75Å; S196-V206 VanDerWaalsContact C-CG2 3.42Å; L197-V206 HydrophobicContact CD2-CG2 3.99Å; L197-V206 HydrophobicContact CG-CG2 4.26Å; V206-W208 HydrophobicContact CG1-CD2 4.14Å; V206-W208 HydrophobicContact CG1-CG 4.02Å; V206-W208 HydrophobicContact CG1-CZ2 4.36Å; V206-W208 PolarHBondContact O-N 2.84Å
207T98.9Very high98.5Very high8 Ų822.3 Ų22.35%0.04912%0.121CC..EExtended strand (participates in β ladder)trans-81.6109158.5-56.70000108.6P83 V84 L140 A141 V142 E194P83-T207 HydrophobicContact CB-CG2 4.18Å; P83-T207 HydrophobicContact CG-CG2 3.99Å; V84-T207 HydrophobicContact CG1-CG2 4.39Å; L140-T207 PolarHBondContact O-N 2.99Å; A141-T207 WeakPolarHBondContact CA-O 3.09Å; V142-T207 PolarHBondContact N-O 2.93Å; V142-T207 VanDerWaalsContact N-O 3.1Å; E194-T207 PolarHBondContact OE1-OG1 3.5Å; E194-T207 PolarHBondContact OE2-OG1 2.89Å
208W98.9Very high98.5Very high3 Ų321 Ų211%0.01111%0.114CC..EExtended strand (participates in β ladder)trans-80.7140.1178.9-8291.1000111.5S29 H107 H119 V142 T192 Y193 S196 T198 V206 V210S29-W208 PolarHBondContact OG-NE1 3.26Å; H107-W208 AromaticContact CE1-CD2 3.69Å; H107-W208 AromaticContact CE1-CE2 3.97Å; H107-W208 AromaticContact CE1-CE3 3.45Å; H107-W208 VanDerWaalsContact CE1-CE3 3.45Å; H107-W208 AromaticContact CE1-CH2 3.9Å; H107-W208 AromaticContact CE1-CZ3 3.55Å; H119-W208 AromaticContact CD2-CH2 3.73Å; H119-W208 AromaticContact CD2-CZ3 3.65Å; H119-W208 AromaticContact CE1-CH2 3.37Å; H119-W208 WeakPolarHBondContact CE1-CH2 3.41Å; H119-W208 AromaticContact CG-CH2 3.88Å; H119-W208 AromaticContact ND1-CH2 3.64Å; H119-W208 AromaticContact NE2-CH2 3.41Å; H119-W208 WeakPolarHBondContact NE2-CH2 3.17Å; H119-W208 AromaticContact NE2-CZ3 3.56Å; V142-W208 HydrophobicContact CB-CD2 4.39Å; V142-W208 HydrophobicContact CB-CE3 4.06Å; V142-W208 HydrophobicContact CB-CH2 4.05Å; V142-W208 HydrophobicContact CB-CZ2 4.4Å; V142-W208 HydrophobicContact CB-CZ3 3.9Å; V142-W208 HydrophobicContact CG1-CE3 4.02Å; V142-W208 HydrophobicContact CG1-CH2 3.56Å; V142-W208 HydrophobicContact CG1-CZ2 4.35Å; V142-W208 HydrophobicContact CG1-CZ3 3.39Å; T192-W208 WeakPolarHBondContact CA-O 3.32Å; T192-W208 VanDerWaalsContact CB-O 3.22Å; T192-W208 WeakPolarHBondContact CB-O 3.3Å; T192-W208 PolarHBondContact OG1-O 3.4Å; Y193-W208 HydrophobicContact CD1-CB 3.67Å; Y193-W208 HydrophobicContact CD1-CG 4.36Å; Y193-W208 HydrophobicContact CE1-CB 3.36Å; Y193-W208 AromaticContact CE1-CD1 3.99Å; Y193-W208 HydrophobicContact CE1-CD2 4.45Å; Y193-W208 AromaticContact CE1-CG 3.62Å; Y193-W208 HydrophobicContact CE1-CG 3.62Å; Y193-W208 AromaticContact CE2-CD1 3.9Å; Y193-W208 HydrophobicContact CE2-CG 4.35Å; Y193-W208 HydrophobicContact CG-CB 4.38Å; Y193-W208 AromaticContact CZ-CD1 3.5Å; Y193-W208 AromaticContact CZ-CG 3.61Å; Y193-W208 PolarHBondContact N-O 3.18Å; Y193-W208 PolarHBondContact O-N 2.84Å; S196-W208 PolarHBondContact O-NE1 3.37Å; S196-W208 VanDerWaalsContact O-NE1 3.07Å; T198-W208 HydrophobicContact CG2-CH2 4.34Å; T198-W208 HydrophobicContact CG2-CZ2 3.81Å; V206-W208 HydrophobicContact CG1-CD2 4.14Å; V206-W208 HydrophobicContact CG1-CG 4.02Å; V206-W208 HydrophobicContact CG1-CZ2 4.36Å; V206-W208 PolarHBondContact O-N 2.84Å; W208-V210 HydrophobicContact CB-CG2 4.5Å; W208-V210 HydrophobicContact CE3-CG2 4.1Å
209I98.9Very high98.5Very high0 Ų023 Ų230%013%0.128CC..EExtended strand (participates in β ladder)trans-130.794.9173-63.7158.9000106.2L47 L79 P83 V142 V143 G144 Y190 W191L47-I209 HydrophobicContact CD1-CG2 3.52Å; L47-I209 HydrophobicContact CD2-CD1 3.91Å; L47-I209 HydrophobicContact CD2-CG1 4.43Å; L47-I209 HydrophobicContact CD2-CG2 3.81Å; L47-I209 HydrophobicContact CG-CG2 4.27Å; L79-I209 HydrophobicContact CD1-CD1 4.46Å; L79-I209 HydrophobicContact CD2-CD1 3.73Å; P83-I209 HydrophobicContact CG-CD1 3.84Å; P83-I209 HydrophobicContact CG-CG1 3.53Å; V142-I209 PolarHBondContact O-N 3.05Å; V143-I209 CarbonylContact C-O 3.48Å; V143-I209 VanDerWaalsContact CA-O 3.28Å; V143-I209 WeakPolarHBondContact CA-O 3.23Å; V143-I209 HydrophobicContact CG2-CB 4.3Å; V143-I209 HydrophobicContact CG2-CD1 4.35Å; V143-I209 HydrophobicContact CG2-CG2 4.33Å; G144-I209 PolarHBondContact N-O 3.22Å; Y190-I209 HydrophobicContact CD1-CG2 4.46Å; Y190-I209 HydrophobicContact CD2-CG2 3.9Å; Y190-I209 HydrophobicContact CG-CG2 3.82Å; W191-I209 CarbonylContact O-C 3.51Å; W191-I209 WeakPolarHBondContact O-CA 2.88Å
210V98.9Very high98.5Very high0 Ų027.9 Ų27.90%015%0.149CC..EExtended strand (participates in β ladder)trans-99.1111.9-176.8-175.40000108.7I33 F146 Y190 W191 W208I33-V210 HydrophobicContact CD1-CB 4Å; I33-V210 HydrophobicContact CD1-CG1 3.98Å; I33-V210 HydrophobicContact CD1-CG2 4.16Å; F146-V210 HydrophobicContact CD2-CG1 4.41Å; F146-V210 HydrophobicContact CE2-CG1 3.57Å; F146-V210 HydrophobicContact CZ-CG1 3.78Å; Y190-V210 CarbonylContact C-O 3.56Å; Y190-V210 VanDerWaalsContact CA-O 3.3Å; Y190-V210 WeakPolarHBondContact CA-O 3.46Å; W191-V210 PolarHBondContact N-O 3.38Å; W191-V210 PolarHBondContact O-N 2.83Å; W208-V210 HydrophobicContact CB-CG2 4.5Å; W208-V210 HydrophobicContact CE3-CG2 4.1Å
211C98.9Very high98.6Very high0 Ų027.5 Ų27.50%015%0.146CC..EExtended strand (participates in β ladder)trans-61.8135.2178.1-68.90000110.8G144 V145 P185G144-C211 PolarHBondContact O-N 2.8Å; V145-C211 HydrophobicContact CG2-CB 4.32Å; P185-C211 HydrophobicContact CG-CB 3.96Å
212K98.5Very high98.7Very high84 Ų8424.5 Ų24.537%0.36513%0.126SC..SBendtrans-68.7-42.6178.2-179.2-168.3-174.9171.80111.8D189 W191 F259D189-K212 HydrophobicContact CB-CB 4.15Å; D189-K212 HydrophobicContact CB-CD 4.15Å; D189-K212 WeakPolarHBondContact O-CB 3.35Å; D189-K212 PolarHBondContact O-N 2.84Å; W191-K212 HydrophobicContact CH2-CB 4.15Å; W191-K212 HydrophobicContact CH2-CG 3.82Å; W191-K212 HydrophobicContact CZ2-CG 4.31Å; W191-K212 HydrophobicContact CZ3-CB 4.04Å; W191-K212 HydrophobicContact CZ3-CG 4.22Å; K212-F259 HydrophobicContact CB-CE1 4.01Å; K212-F259 HydrophobicContact CB-CZ 4.25Å; K212-F259 HydrophobicContact CD-CD1 4.18Å; K212-F259 HydrophobicContact CD-CD2 4.14Å; K212-F259 HydrophobicContact CD-CE1 3.78Å; K212-F259 HydrophobicContact CD-CE2 3.75Å; K212-F259 HydrophobicContact CD-CG 4.33Å; K212-F259 HydrophobicContact CD-CZ 3.53Å; K212-F259 HydrophobicContact CG-CE1 4.2Å; K212-F259 HydrophobicContact CG-CZ 3.96Å; K212-F259 VanDerWaalsContact NZ-CD2 3.33Å
213E98.6Very high98.7Very high81 Ų8127.1 Ų27.138%0.37915%0.148SC..SBendtrans-85.7125.8-178.1-177.1173.5-162.800110.5P185 C187P185-E213 HydrophobicContact CB-CB 3.77Å; P185-E213 HydrophobicContact CB-CG 3.81Å; P185-E213 WeakPolarHBondContact CB-O 3.44Å; P185-E213 HydrophobicContact CG-CB 4.32Å; P185-E213 WeakPolarHBondContact CG-O 3.18Å; C187-E213 WeakPolarHBondContact CB-OE2 3.4Å; C187-E213 PolarHBondContact N-OE2 2.95Å
214P98.7Very high98.8Very high18 Ų1828.7 Ų28.712%0.11715%0.152CC..PPolyproline II helixtrans-80.1151.117232.6-35.7000111.6Y114 F146 K148Y114-P214 HydrophobicContact CD1-CB 4.38Å; Y114-P214 HydrophobicContact CE1-CB 4Å; Y114-P214 HydrophobicContact CE1-CG 4.06Å; F146-P214 HydrophobicContact CB-CB 3.83Å; F146-P214 CarbonylContact O-C 3.58Å; F146-P214 WeakPolarHBondContact O-CA 3.34Å; F146-P214 WeakPolarHBondContact O-CB 3.44Å; K148-P214 HydrophobicContact CB-CB 4.24Å; K148-P214 HydrophobicContact CB-CG 4.36Å; K148-P214 HydrophobicContact CD-CB 4.23Å; K148-P214 HydrophobicContact CD-CG 3.58Å; K148-P214 HydrophobicContact CG-CB 4.03Å; K148-P214 HydrophobicContact CG-CG 3.95Å
215I98.8Very high98.8Very high13 Ų1327.5 Ų27.57%0.06715%0.147CC..EExtended strand (participates in β ladder)trans-84.7154.716665.1174.9000110.7V145 F146 L147 K148 P185V145-I215 HydrophobicContact CG1-CB 4.5Å; V145-I215 HydrophobicContact CG1-CD1 4.41Å; V145-I215 HydrophobicContact CG1-CG1 4.12Å; V145-I215 HydrophobicContact CG1-CG2 3.86Å; F146-I215 PolarHBondContact O-N 2.83Å; L147-I215 CarbonylContact C-O 3.59Å; L147-I215 WeakPolarHBondContact CA-O 3.26Å; L147-I215 HydrophobicContact CG-CD1 4.1Å; L147-I215 HydrophobicContact CG-CG1 3.9Å; K148-I215 PolarHBondContact N-O 2.97Å; P185-I215 HydrophobicContact CB-CG2 4.22Å
216S98.5Very high98.8Very high34 Ų3429.2 Ų29.224%0.23815%0.153CC..EExtended strand (participates in β ladder)trans-76.1154.4174-162.40000111.1K148 G150 E151 N153K148-S216 CarbonylContact O-C 3.53Å; K148-S216 WeakPolarHBondContact O-CA 3.33Å; G150-S216 WeakPolarHBondContact CA-OG 3.4Å; E151-S216 PolarHBondContact N-OG 3.43Å; E151-S216 PolarHBondContact O-OG 3.08Å; N153-S216 WeakPolarHBondContact CB-O 3.23Å; N153-S216 PolarHBondContact ND2-O 2.93Å
217V98.8Very high98.8Very high0 Ų031.1 Ų31.10%017%0.166CC..EExtended strand (participates in β ladder)trans-152142.8166.863.40000108.4L147 K148 I149 G150 E151 L156 Q221 M222L147-V217 HydrophobicContact CB-CB 4.49Å; L147-V217 HydrophobicContact CB-CG1 3.83Å; L147-V217 HydrophobicContact CD2-CB 4.08Å; L147-V217 HydrophobicContact CD2-CG1 4.11Å; L147-V217 HydrophobicContact CD2-CG2 4.32Å; K148-V217 PolarHBondContact O-N 2.84Å; I149-V217 WeakPolarHBondContact CA-O 3.13Å; I149-V217 HydrophobicContact CD1-CG1 4.29Å; G150-V217 PolarHBondContact N-O 3.21Å; E151-V217 CarbonylContact O-C 3.52Å; L156-V217 HydrophobicContact CD1-CB 4.02Å; L156-V217 HydrophobicContact CD1-CG2 3.71Å; V217-Q221 HydrophobicContact CG2-CB 3.63Å; V217-M222 HydrophobicContact CG1-CG 3.8Å; V217-M222 HydrophobicContact CG1-SD 3.9Å; V217-M222 HydrophobicContact CG2-CG 3.97Å; V217-M222 HydrophobicContact CG2-SD 4Å
218S98.8Very high98.7Very high4 Ų430.7 Ų30.73%0.02816%0.164CC..  trans-80.3157.8174.765.20000111.8E220 Q221 M222S218-E220 WeakPolarHBondContact CB-OE2 3.38Å; S218-E220 PolarHBondContact O-N 3.01Å; S218-Q221 PolarHBondContact O-N 3.11Å; S218-Q221 WeakPolarHBondContact OG-CG 3.32Å; S218-Q221 PolarHBondContact OG-N 2.64Å; S218-Q221 VanDerWaalsContact OG-N 3.16Å; S218-M222 PolarHBondContact O-N 2.81Å
219S98.8Very high98.7Very high46 Ų4630.8 Ų30.832%0.32217%0.165SC..Hα-helixtrans-60.8-32.7173.1-660000111.9D101 M222 A223D101-S219 WeakPolarHBondContact OD2-CB 3.42Å; D101-S219 PolarHBondContact OD2-OG 2.94Å; S219-M222 PolarHBondContact O-N 3.33Å; S219-A223 WeakPolarHBondContact O-CB 3.15Å; S219-A223 PolarHBondContact O-N 2.96Å
220E98.8Very high98.7Very high137 Ų13732.6 Ų32.664%0.6417%0.173SC*.Hα-helixtrans-66.6-42.9175.7-66.972.1-159.900111.9S218 A223 K224S218-E220 WeakPolarHBondContact CB-OE2 3.38Å; S218-E220 PolarHBondContact O-N 3.01Å; E220-A223 WeakPolarHBondContact O-CB 3.46Å; E220-A223 PolarHBondContact O-N 2.92Å; E220-K224 PolarHBondContact O-N 2.87Å
221Q98.8Very high98.6Very high4 Ų433 Ų332%0.01918%0.175CC..Hα-helixtrans-63-45.3173-75.1178.8-40.300110.2E152 N153 V160 V217 S218 A223 K224 F225E152-Q221 HydrophobicContact CG-CG 4.35Å; N153-Q221 PolarHBondContact O-NE2 3.27Å; V160-Q221 HydrophobicContact CG2-CG 4.38Å; V217-Q221 HydrophobicContact CG2-CB 3.63Å; S218-Q221 PolarHBondContact O-N 3.11Å; S218-Q221 WeakPolarHBondContact OG-CG 3.32Å; S218-Q221 PolarHBondContact OG-N 2.64Å; S218-Q221 VanDerWaalsContact OG-N 3.16Å; Q221-A223 VanDerWaalsContact C-N 3.29Å; Q221-A223 PolarHBondContact O-N 3.47Å; Q221-K224 WeakPolarHBondContact O-CA 3.19Å; Q221-K224 VanDerWaalsContact O-CB 3.32Å; Q221-K224 WeakPolarHBondContact O-CB 3.24Å; Q221-K224 PolarHBondContact O-N 2.94Å; Q221-F225 VanDerWaalsContact O-CD2 3.28Å; Q221-F225 WeakPolarHBondContact O-CD2 3.3Å; Q221-F225 PolarHBondContact O-N 3.28Å
222M98.9Very high98.5Very high0 Ų033.5 Ų33.50%018%0.18CC..Hα-helixtrans-61.3-35.6175.6-74.1-53.7-51.700113.1W97 P115 A116 I149 V217 S218 S219 K224 F225 R226W97-M222 HydrophobicContact CB-CE 3.79Å; P115-M222 HydrophobicContact CB-CE 4.23Å; P115-M222 HydrophobicContact CB-CG 4.41Å; P115-M222 HydrophobicContact CB-SD 4.4Å; A116-M222 HydrophobicContact CB-CE 3.9Å; A116-M222 HydrophobicContact CB-SD 4.09Å; I149-M222 HydrophobicContact CD1-CG 3.91Å; V217-M222 HydrophobicContact CG1-CG 3.8Å; V217-M222 HydrophobicContact CG1-SD 3.9Å; V217-M222 HydrophobicContact CG2-CG 3.97Å; V217-M222 HydrophobicContact CG2-SD 4Å; S218-M222 PolarHBondContact O-N 2.81Å; S219-M222 PolarHBondContact O-N 3.33Å; M222-K224 PolarHBondContact O-N 2.98Å; M222-F225 HydrophobicContact CE-CB 4.46Å; M222-F225 WeakPolarHBondContact O-CB 3.38Å; M222-F225 PolarHBondContact O-N 3.02Å; M222-R226 WeakPolarHBondContact O-CG 3.18Å; M222-R226 PolarHBondContact O-N 2.76Å; M222-R226 VanDerWaalsContact O-N 3.15Å
223A98.8Very high98.3Very high54 Ų5438 Ų3845%0.44620%0.203SC..Hα-helixtrans-62.1-32.7173.600000112.3S219 E220 Q221 R226 S227S219-A223 WeakPolarHBondContact O-CB 3.15Å; S219-A223 PolarHBondContact O-N 2.96Å; E220-A223 WeakPolarHBondContact O-CB 3.46Å; E220-A223 PolarHBondContact O-N 2.92Å; Q221-A223 VanDerWaalsContact C-N 3.29Å; Q221-A223 PolarHBondContact O-N 3.47Å; A223-R226 PolarHBondContact O-N 2.95Å; A223-S227 PolarHBondContact O-N 3.27Å
224K98.8Very high98.1Very high90 Ų9038.2 Ų38.239%0.39123%0.226SC..Hα-helixtrans-67.9-41.4173.5-68.9-71.5-169.61690112.2V160 F163 E220 Q221 M222 R226 S227V160-K224 HydrophobicContact CG1-CB 3.75Å; V160-K224 HydrophobicContact CG1-CD 4.44Å; V160-K224 HydrophobicContact CG1-CG 3.7Å; F163-K224 HydrophobicContact CD2-CB 3.98Å; F163-K224 WeakPolarHBondContact CD2-O 3.38Å; F163-K224 HydrophobicContact CE2-CB 4.35Å; E220-K224 PolarHBondContact O-N 2.87Å; Q221-K224 WeakPolarHBondContact O-CA 3.19Å; Q221-K224 VanDerWaalsContact O-CB 3.32Å; Q221-K224 WeakPolarHBondContact O-CB 3.24Å; Q221-K224 PolarHBondContact O-N 2.94Å; M222-K224 PolarHBondContact O-N 2.98Å; K224-R226 VanDerWaalsContact C-N 3.28Å; K224-R226 PolarHBondContact O-N 2.98Å; K224-S227 WeakPolarHBondContact O-CB 3.36Å; K224-S227 PolarHBondContact O-N 3.42Å; K224-S227 PolarHBondContact O-OG 2.84Å
225F98.8Very high97.9Very high0 Ų043.1 Ų43.10%025%0.248CC..Hα-helixtrans-56.6-46.3174-79.2-120.8000110.7F66 F95 W97 V160 F163 Q221 M222 S227 L228F66-F225 AromaticContact CE1-CD1 3.79Å; F66-F225 HydrophobicContact CE1-CD1 3.79Å; F66-F225 AromaticContact CE1-CE1 3.57Å; F66-F225 HydrophobicContact CE1-CE1 3.57Å; F66-F225 HydrophobicContact CE1-CZ 4.25Å; F66-F225 HydrophobicContact CZ-CD1 4.4Å; F66-F225 AromaticContact CZ-CE1 3.72Å; F66-F225 HydrophobicContact CZ-CE1 3.72Å; F66-F225 HydrophobicContact CZ-CZ 4.09Å; F95-F225 HydrophobicContact CB-CE1 4.05Å; F95-F225 AromaticContact CD1-CE1 3.84Å; F95-F225 HydrophobicContact CD1-CE1 3.84Å; F95-F225 HydrophobicContact CD1-CZ 4.43Å; F95-F225 HydrophobicContact CD2-CE1 4.16Å; F95-F225 HydrophobicContact CE1-CE1 4.24Å; F95-F225 HydrophobicContact CE1-CZ 4.38Å; F95-F225 AromaticContact CG-CE1 3.78Å; F95-F225 HydrophobicContact CG-CE1 3.78Å; W97-F225 HydrophobicContact CD2-CB 4.22Å; W97-F225 HydrophobicContact CD2-CD1 4.11Å; W97-F225 AromaticContact CE3-CD1 3.91Å; W97-F225 HydrophobicContact CE3-CD1 3.91Å; W97-F225 HydrophobicContact CG-CB 4.28Å; W97-F225 HydrophobicContact CZ3-CD1 4.3Å; V160-F225 HydrophobicContact CG2-CE2 4.01Å; F163-F225 HydrophobicContact CE2-CB 4.29Å; F163-F225 HydrophobicContact CE2-CD1 4.47Å; F163-F225 AromaticContact CE2-CD2 3.44Å; F163-F225 HydrophobicContact CE2-CD2 3.44Å; F163-F225 VanDerWaalsContact CE2-CD2 3.44Å; F163-F225 AromaticContact CE2-CE2 3.79Å; F163-F225 HydrophobicContact CE2-CE2 3.79Å; F163-F225 AromaticContact CE2-CG 3.82Å; F163-F225 HydrophobicContact CE2-CG 3.82Å; F163-F225 HydrophobicContact CE2-CZ 4.45Å; F163-F225 HydrophobicContact CZ-CD1 4.39Å; F163-F225 AromaticContact CZ-CD2 3.87Å; F163-F225 HydrophobicContact CZ-CD2 3.87Å; F163-F225 HydrophobicContact CZ-CE1 4.33Å; F163-F225 AromaticContact CZ-CE2 3.8Å; F163-F225 HydrophobicContact CZ-CE2 3.8Å; F163-F225 HydrophobicContact CZ-CG 4.16Å; F163-F225 HydrophobicContact CZ-CZ 4.04Å; Q221-F225 VanDerWaalsContact O-CD2 3.28Å; Q221-F225 WeakPolarHBondContact O-CD2 3.3Å; Q221-F225 PolarHBondContact O-N 3.28Å; M222-F225 HydrophobicContact CE-CB 4.46Å; M222-F225 WeakPolarHBondContact O-CB 3.38Å; M222-F225 PolarHBondContact O-N 3.02Å; F225-S227 PolarHBondContact O-N 2.8Å; F225-S227 VanDerWaalsContact O-N 3.13Å; F225-L228 PolarHBondContact O-N 3.38Å
226R98.8Very high97.8Very high37 Ų3746.8 Ų46.814%0.1428%0.28CS..THydrogen-bonded Turntrans-69.7-4.6179.3-61175.2-170.5120.94.7114.7G98 S99 S100 D101 M222 A223 K224 V241G98-R226 PolarHBondContact O-NE 3.39Å; S99-R226 WeakPolarHBondContact O-CD 3.48Å; S99-R226 PolarHBondContact O-NE 3Å; S100-R226 PolarHBondContact O-NH2 3.12Å; D101-R226 IonicContact OD1-CZ 3.64Å; D101-R226 IonicContact OD1-NH1 3.42Å; D101-R226 PolarHBondContact OD1-NH1 3.01Å; D101-R226 IonicContact OD1-NH2 3.19Å; D101-R226 PolarHBondContact OD1-NH2 2.89Å; M222-R226 WeakPolarHBondContact O-CG 3.18Å; M222-R226 PolarHBondContact O-N 2.76Å; M222-R226 VanDerWaalsContact O-N 3.15Å; A223-R226 PolarHBondContact O-N 2.95Å; K224-R226 VanDerWaalsContact C-N 3.28Å; K224-R226 PolarHBondContact O-N 2.98Å; R226-V241 HydrophobicContact CB-CG1 3.89Å; R226-V241 HydrophobicContact CG-CG1 3.98Å
227S98.4Very high97.7Very high40 Ų4052 Ų5228%0.2830%0.3SS..THydrogen-bonded Turntrans-92-13.9178.579.30000114A223 K224 F225A223-S227 PolarHBondContact O-N 3.27Å; K224-S227 WeakPolarHBondContact O-CB 3.36Å; K224-S227 PolarHBondContact O-N 3.42Å; K224-S227 PolarHBondContact O-OG 2.84Å; F225-S227 PolarHBondContact O-N 2.8Å; F225-S227 VanDerWaalsContact O-N 3.13Å
228L98.8Very high97.6Very high0 Ų055 Ų550%032%0.321CS..SBendtrans-64157.4168.9-64.3176000110.1F66 W97 F163 I166 F225 M240F66-L228 HydrophobicContact CB-CD1 4.21Å; F66-L228 HydrophobicContact CD1-CD1 3.6Å; F66-L228 HydrophobicContact CE1-CD1 4.43Å; F66-L228 HydrophobicContact CG-CD1 4.31Å; W97-L228 HydrophobicContact CH2-CD1 4.12Å; W97-L228 HydrophobicContact CZ2-CD1 4.21Å; F163-L228 HydrophobicContact CB-CD2 3.93Å; F163-L228 HydrophobicContact CD1-CD1 4.46Å; F163-L228 HydrophobicContact CD1-CD2 4.48Å; F163-L228 HydrophobicContact CD2-CD1 4.42Å; F163-L228 HydrophobicContact CD2-CG 4.36Å; F163-L228 HydrophobicContact CE1-CD1 4.48Å; F163-L228 HydrophobicContact CE2-CD1 4.47Å; F163-L228 HydrophobicContact CG-CD1 4.43Å; F163-L228 HydrophobicContact CG-CD2 4.1Å; F163-L228 HydrophobicContact CG-CG 4.36Å; F163-L228 HydrophobicContact CZ-CD1 4.49Å; I166-L228 HydrophobicContact CD1-CD2 4.27Å; I166-L228 HydrophobicContact CG1-CD2 4.28Å; F225-L228 PolarHBondContact O-N 3.38Å; L228-M240 HydrophobicContact CB-CB 4.09Å; L228-M240 HydrophobicContact CB-SD 4.44Å; L228-M240 VanDerWaalsContact O-CB 3.31Å; L228-M240 WeakPolarHBondContact O-CB 3.48Å; L228-M240 PolarHBondContact O-N 2.99Å
229L98.6Very high97.6Very high5 Ų558 Ų583%0.02634%0.341CS..BIsolated β-bridgetrans-119.4138.5-177.3-54.8-179.1000111.2N61 K167 T168 E237 C238 M240N61-L229 PolarHBondContact ND2-O 2.86Å; N61-L229 VanDerWaalsContact ND2-O 3.09Å; K167-L229 HydrophobicContact CG-CD1 4.42Å; K167-L229 HydrophobicContact CG-CG 4.27Å; K167-L229 PolarHBondContact O-N 3.47Å; T168-L229 HydrophobicContact CG2-CD1 3.99Å; L229-E237 HydrophobicContact CD1-CB 4.22Å; L229-E237 HydrophobicContact CD1-CG 3.9Å; L229-E237 HydrophobicContact CD2-CB 4.43Å; L229-C238 CarbonylContact C-O 3.5Å; L229-C238 VanDerWaalsContact CA-O 3.26Å; L229-C238 WeakPolarHBondContact CA-O 3.4Å; L229-M240 WeakPolarHBondContact O-CE 3.16Å
230F98Very high97.6Very high38 Ų3855.8 Ų55.817%0.16733%0.326CS..SBendtrans-67.7-28165-70.4-59.1000111.8Y7 G63 K169 C238 C239 M240 V241 N243Y7-F230 AromaticContact CD2-CE1 3.92Å; Y7-F230 HydrophobicContact CD2-CE1 3.92Å; Y7-F230 AromaticContact CD2-CZ 3.93Å; Y7-F230 HydrophobicContact CD2-CZ 3.93Å; Y7-F230 HydrophobicContact CE2-CE1 4.47Å; G63-F230 VanDerWaalsContact O-CD1 3.25Å; G63-F230 WeakPolarHBondContact O-CD1 3.44Å; K169-F230 WeakPolarHBondContact CB-O 3.37Å; F230-C238 HydrophobicContact CB-CB 4.43Å; F230-C238 PolarHBondContact N-O 2.63Å; F230-C239 VanDerWaalsContact CD2-O 3.29Å; F230-C239 WeakPolarHBondContact CD2-O 3.35Å; F230-C239 WeakPolarHBondContact CE2-O 3.47Å; F230-M240 HydrophobicContact CD1-CB 4.21Å; F230-M240 HydrophobicContact CD1-CE 3.91Å; F230-M240 HydrophobicContact CD1-CG 3.74Å; F230-M240 HydrophobicContact CD1-SD 4.48Å; F230-M240 HydrophobicContact CD2-CB 4.38Å; F230-M240 HydrophobicContact CE1-CB 4.32Å; F230-M240 HydrophobicContact CE1-CE 4.44Å; F230-M240 HydrophobicContact CE1-CG 3.53Å; F230-M240 HydrophobicContact CE1-SD 4.46Å; F230-M240 HydrophobicContact CE2-CB 4.46Å; F230-M240 HydrophobicContact CE2-CG 4.38Å; F230-M240 HydrophobicContact CG-CB 4.27Å; F230-M240 HydrophobicContact CG-CG 4.29Å; F230-M240 HydrophobicContact CZ-CB 4.44Å; F230-M240 HydrophobicContact CZ-CG 3.88Å; F230-V241 WeakPolarHBondContact CE2-O 3.44Å; F230-N243 HydrophobicContact CE1-CB 3.9Å; F230-N243 HydrophobicContact CZ-CB 3.77Å
231S97.2Very high97.6Very high8 Ų851.2 Ų51.26%0.05631%0.307CS..SBendtrans-81.2147.8-177.156.40000112.2T168 K169 E235 A236 C238T168-S231 WeakPolarHBondContact CB-O 3.41Å; K169-S231 PolarHBondContact N-O 3.34Å; S231-E235 WeakPolarHBondContact CA-OE2 3.33Å; S231-A236 VanDerWaalsContact CB-O 3.24Å; S231-A236 WeakPolarHBondContact CB-O 3.12Å; S231-A236 PolarHBondContact OG-O 2.96Å; S231-C238 PolarHBondContact OG-N 2.62Å; S231-C238 VanDerWaalsContact OG-N 3.12Å
232G96.9Very high97.5Very high10 Ų1053.6 Ų53.610%0.10332%0.32CS..BIsolated β-bridgetrans-77.3174.4173.500000113.2G234 E235G232-G234 PolarHBondContact O-N 2.9Å; G232-E235 PolarHBondContact N-OE2 2.83Å; G232-E235 WeakPolarHBondContact O-CB 3.15Å; G232-E235 PolarHBondContact O-N 2.83Å
233E93.9Very high97.5Very high180 Ų18053.6 Ų53.684%0.84132%0.32SS*.THydrogen-bonded Turntrans-61.9132.1173.7-171.4177.6-176.700110.9E235E233-E235 VanDerWaalsContact C-N 3.26Å; E233-E235 PolarHBondContact O-N 2.9Å
234G94.4Very high97.5Very high85 Ų8552.9 Ų52.988%0.87631%0.306SS*.THydrogen-bonded Turntrans80.9-3.6-178.600000115.3G232G232-G234 PolarHBondContact O-N 2.9Å
235E95.6Very high97.5Very high121 Ų12148.8 Ų48.857%0.56529%0.288SS*.SBendtrans-86.4165.4170.7-63.2-177.9166.600111.4S231 G232 E233 E237S231-E235 WeakPolarHBondContact CA-OE2 3.33Å; G232-E235 PolarHBondContact N-OE2 2.83Å; G232-E235 WeakPolarHBondContact O-CB 3.15Å; G232-E235 PolarHBondContact O-N 2.83Å; E233-E235 VanDerWaalsContact C-N 3.26Å; E233-E235 PolarHBondContact O-N 2.9Å; E235-E237 PolarHBondContact O-N 3.48Å
236A96.3Very high97.5Very high90 Ų9051.8 Ų51.874%0.74431%0.307SS*.PPolyproline II helixtrans-64.3126.9173.100000109.9S231 C238S231-A236 VanDerWaalsContact CB-O 3.24Å; S231-A236 WeakPolarHBondContact CB-O 3.12Å; S231-A236 PolarHBondContact OG-O 2.96Å; A236-C238 PolarHBondContact O-N 3.02Å
237E96.4Very high97.5Very high142 Ų14252.5 Ų52.566%0.66432%0.317SS*.PPolyproline II helixtrans-56.6125.2-177-67.1-166.7148.200111.3K167 L229 E235K167-E237 IonicContact NZ-OE1 3.92Å; L229-E237 HydrophobicContact CD1-CB 4.22Å; L229-E237 HydrophobicContact CD1-CG 3.9Å; L229-E237 HydrophobicContact CD2-CB 4.43Å; E235-E237 PolarHBondContact O-N 3.48Å
238C96.9Very high97.5Very high64 Ų6452.5 Ų52.543%0.43231%0.312SS..  trans-129.5102.7174.5-1750000108.4L229 F230 S231 A236 M240L229-C238 CarbonylContact C-O 3.5Å; L229-C238 VanDerWaalsContact CA-O 3.26Å; L229-C238 WeakPolarHBondContact CA-O 3.4Å; F230-C238 HydrophobicContact CB-CB 4.43Å; F230-C238 PolarHBondContact N-O 2.63Å; S231-C238 PolarHBondContact OG-N 2.62Å; S231-C238 VanDerWaalsContact OG-N 3.12Å; A236-C238 PolarHBondContact O-N 3.02Å; C238-M240 PolarHBondContact O-N 3.34Å
239C97.8Very high97.5Very high67 Ų6756.3 Ų56.345%0.45334%0.337SS..BIsolated β-bridgetrans-56.8133.6179.7-61.50000110.8F230 V241F230-C239 VanDerWaalsContact CD2-O 3.29Å; F230-C239 WeakPolarHBondContact CD2-O 3.35Å; F230-C239 WeakPolarHBondContact CE2-O 3.47Å; C239-V241 VanDerWaalsContact C-N 3.34Å; C239-V241 HydrophobicContact CB-CG1 4.31Å; C239-V241 PolarHBondContact O-N 3.02Å
240M98.4Very high97.5Very high0 Ų059 Ų590%035%0.352CS..  trans-74.291.1173.5-169.8174.3-64.200107.8N61 S65 W97 L228 L229 F230 C238N61-M240 VanDerWaalsContact OD1-CE 3.26Å; N61-M240 WeakPolarHBondContact OD1-CE 3.49Å; S65-M240 WeakPolarHBondContact CA-SD 3.18Å; W97-M240 HydrophobicContact CH2-CG 4.03Å; W97-M240 HydrophobicContact CH2-SD 3.39Å; W97-M240 WeakPolarHBondContact CH2-SD 3.38Å; W97-M240 HydrophobicContact CZ2-CB 3.99Å; W97-M240 HydrophobicContact CZ2-CG 3.41Å; W97-M240 VanDerWaalsContact CZ2-CG 3.41Å; W97-M240 HydrophobicContact CZ2-SD 3.38Å; W97-M240 WeakPolarHBondContact CZ2-SD 3.38Å; W97-M240 PolarHBondContact NE1-O 3.11Å; L228-M240 HydrophobicContact CB-CB 4.09Å; L228-M240 HydrophobicContact CB-SD 4.44Å; L228-M240 VanDerWaalsContact O-CB 3.31Å; L228-M240 WeakPolarHBondContact O-CB 3.48Å; L228-M240 PolarHBondContact O-N 2.99Å; L229-M240 WeakPolarHBondContact O-CE 3.16Å; F230-M240 HydrophobicContact CD1-CB 4.21Å; F230-M240 HydrophobicContact CD1-CE 3.91Å; F230-M240 HydrophobicContact CD1-CG 3.74Å; F230-M240 HydrophobicContact CD1-SD 4.48Å; F230-M240 HydrophobicContact CD2-CB 4.38Å; F230-M240 HydrophobicContact CE1-CB 4.32Å; F230-M240 HydrophobicContact CE1-CE 4.44Å; F230-M240 HydrophobicContact CE1-CG 3.53Å; F230-M240 HydrophobicContact CE1-SD 4.46Å; F230-M240 HydrophobicContact CE2-CB 4.46Å; F230-M240 HydrophobicContact CE2-CG 4.38Å; F230-M240 HydrophobicContact CG-CB 4.27Å; F230-M240 HydrophobicContact CG-CG 4.29Å; F230-M240 HydrophobicContact CZ-CB 4.44Å; F230-M240 HydrophobicContact CZ-CG 3.88Å; C238-M240 PolarHBondContact O-N 3.34Å
241V98.4Very high97.5Very high40 Ų4062.4 Ų62.424%0.24237%0.366CS..  trans-135.9155.6174.3-63.10000108.9R226 F230 C239 N243R226-V241 HydrophobicContact CB-CG1 3.89Å; R226-V241 HydrophobicContact CG-CG1 3.98Å; F230-V241 WeakPolarHBondContact CE2-O 3.44Å; C239-V241 VanDerWaalsContact C-N 3.34Å; C239-V241 HydrophobicContact CB-CG1 4.31Å; C239-V241 PolarHBondContact O-N 3.02Å; V241-N243 PolarHBondContact O-N 3.13Å
242D98.6Very high97.5Very high54 Ų5466.1 Ų66.129%0.28941%0.406SS..  trans56.138.1179.9-56.4-41.7000112.7W97 G98 S99 H103 Y244W97-D242 WeakPolarHBondContact O-CA 3.34Å; W97-D242 PolarHBondContact O-N 2.8Å; W97-D242 VanDerWaalsContact O-N 3.15Å; G98-D242 WeakPolarHBondContact CA-OD1 3.43Å; S99-D242 WeakPolarHBondContact CB-OD2 3.14Å; S99-D242 PolarHBondContact N-OD1 3.19Å; S99-D242 PolarHBondContact OG-OD1 3.05Å; S99-D242 PolarHBondContact OG-OD2 3.19Å; H103-D242 IonicContact CD2-OD1 3.11Å; H103-D242 IonicContact NE2-OD1 3.72Å; H103-D242 PolarHBondContact NE2-OD1 3.02Å; H103-D242 VanDerWaalsContact NE2-OD1 3.11Å; D242-Y244 HydrophobicContact CB-CD1 4.37Å; D242-Y244 HydrophobicContact CB-CE1 3.91Å; D242-Y244 PolarHBondContact O-N 2.91Å; D242-Y244 WeakPolarHBondContact OD1-CE1 3.41Å
243N98.7Very high97.5Very high0 Ų067 Ų670%041%0.406CS..  trans-8134.1178.871.2-26.5000112.4Y7 H64 F95 H96 W97 F230 V241Y7-N243 HydrophobicContact CD2-CB 3.89Å; Y7-N243 WeakPolarHBondContact CE1-O 3.24Å; Y7-N243 HydrophobicContact CE2-CB 3.73Å; Y7-N243 HydrophobicContact CG-CB 4.49Å; Y7-N243 VanDerWaalsContact CZ-C 3.4Å; Y7-N243 PolarHBondContact OH-O 3.45Å; Y7-N243 VanDerWaalsContact OH-O 3.08Å; H64-N243 WeakPolarHBondContact O-CB 3.27Å; H64-N243 PolarHBondContact O-ND2 2.87Å; F95-N243 PolarHBondContact O-ND2 3.04Å; H96-N243 WeakPolarHBondContact CA-OD1 3.11Å; H96-N243 PolarHBondContact ND1-O 2.92Å; W97-N243 WeakPolarHBondContact CZ3-ND2 3.49Å; W97-N243 PolarHBondContact N-OD1 3.46Å; W97-N243 PolarHBondContact O-N 3.09Å; W97-N243 PolarHBondContact O-OD1 3.46Å; W97-N243 VanDerWaalsContact O-OD1 3.07Å; F230-N243 HydrophobicContact CE1-CB 3.9Å; F230-N243 HydrophobicContact CZ-CB 3.77Å; V241-N243 PolarHBondContact O-N 3.13Å
244Y98.7Very high97.7Very high39 Ų3962.7 Ų62.715%0.15339%0.392CS..  trans-119.6143.6-175.968.1-94000111.2H103 G104 D242H103-Y244 AromaticContact CD2-CE1 3.74Å; H103-Y244 AromaticContact CD2-CZ 3.84Å; H103-Y244 PolarHBondContact CD2-OH 2.78Å; H103-Y244 VanDerWaalsContact CD2-OH 3.24Å; G104-Y244 WeakPolarHBondContact O-CB 3.33Å; D242-Y244 HydrophobicContact CB-CD1 4.37Å; D242-Y244 HydrophobicContact CB-CE1 3.91Å; D242-Y244 PolarHBondContact O-N 2.91Å; D242-Y244 WeakPolarHBondContact OD1-CE1 3.41Å
245R98.8Very high97.9Very high4 Ų459 Ų592%0.01535%0.353CS..PPolyproline II helixtrans-84.3138.3174.3-163.6-168.6-170.7-171.71.5110.4P13 W16 A23 S29 P30 E106 T198P13-R245 HydrophobicContact CB-CG 4.05Å; P13-R245 HydrophobicContact CG-CG 4.27Å; W16-R245 HydrophobicContact CH2-CB 4.38Å; W16-R245 HydrophobicContact CH2-CG 4.32Å; W16-R245 HydrophobicContact CZ3-CB 4.21Å; W16-R245 HydrophobicContact CZ3-CG 3.74Å; A23-R245 PolarHBondContact O-NH2 2.83Å; A23-R245 VanDerWaalsContact O-NH2 3.07Å; S29-R245 WeakPolarHBondContact O-CD 2.98Å; S29-R245 PolarHBondContact O-NH1 3.42Å; P30-R245 VanDerWaalsContact CG-O 3.31Å; P30-R245 WeakPolarHBondContact CG-O 3.21Å; E106-R245 WeakPolarHBondContact OE1-CA 3.03Å; E106-R245 WeakPolarHBondContact OE1-CB 3.29Å; E106-R245 PolarHBondContact OE1-N 2.92Å; T198-R245 WeakPolarHBondContact O-CD 3.28Å
246P98.6Very high98Very high63 Ų6356.8 Ų56.841%0.40934%0.339SS..PPolyproline II helixtrans-61.9153.4172.5-24.534000113.3Q248P246-Q248 PolarHBondContact O-N 3.12Å; P246-Q248 PolarHBondContact O-NE2 3.05Å
247P98.7Very high98.1Very high52 Ų5252.7 Ų52.734%0.33831%0.305SS..PPolyproline II helixtrans-52.5132.7171.9-2936.3000113.3T108T108-P247 HydrophobicContact CG2-CG 4Å
248Q98.8Very high98.2Very high40 Ų4047 Ų4719%0.18728%0.282CS..PPolyproline II helixtrans-96.9158.2178.4-56.8-60.1-58.100110.7Q28 P30 P246 L250Q28-Q248 HydrophobicContact CB-CB 3.95Å; Q28-Q248 HydrophobicContact CB-CG 3.93Å; P30-Q248 WeakPolarHBondContact O-CB 3.39Å; P30-Q248 PolarHBondContact O-N 2.78Å; P246-Q248 PolarHBondContact O-N 3.12Å; P246-Q248 PolarHBondContact O-NE2 3.05Å; Q248-L250 PolarHBondContact O-N 3.27Å
249P98.5Very high98.3Very high80 Ų8045.2 Ų45.252%0.51927%0.266SS..PPolyproline II helixtrans-59.1130.9177.7-25.935.8000112.7K251 R253P249-K251 HydrophobicContact CB-CG 3.99Å; P249-K251 PolarHBondContact O-N 2.73Å; P249-R253 PolarHBondContact O-NH2 3.18Å
250L98.2Very high97.8Very high63 Ų6352 Ų5233%0.3329%0.291SS..  trans-61.3-33.3176.5-175.462.3000112.1I31 Q248 R253 V255I31-L250 HydrophobicContact CD1-CD1 3.62Å; I31-L250 HydrophobicContact CG2-CD1 4.35Å; Q248-L250 PolarHBondContact O-N 3.27Å; L250-R253 HydrophobicContact CD1-CB 3.89Å; L250-R253 HydrophobicContact CG-CB 4.32Å; L250-R253 WeakPolarHBondContact O-CB 3.45Å; L250-R253 PolarHBondContact O-N 2.97Å; L250-R253 PolarHBondContact O-NE 2.91Å; L250-V255 HydrophobicContact CD1-CG2 4.15Å
251K97.6Very high97.8Very high108 Ų10854.6 Ų54.647%0.4731%0.306SS..THydrogen-bonded Turntrans54-140.8-176.8-62.9178.1174.5177.70110.3N24 G25 P26 P249 R253N24-K251 PolarHBondContact O-NZ 3.18Å; G25-K251 PolarHBondContact O-NZ 2.85Å; P26-K251 HydrophobicContact CB-CD 4.49Å; P26-K251 WeakPolarHBondContact O-CD 3.17Å; P249-K251 HydrophobicContact CB-CG 3.99Å; P249-K251 PolarHBondContact O-N 2.73Å; K251-R253 PolarHBondContact O-N 2.74Å
252G96.5Very high97.8Very high87 Ų8755.4 Ų55.490%0.89731%0.309SS*.THydrogen-bonded Turntrans-78.915.1-176.600000115.4
253R97.9Very high97.7Very high28 Ų2855.4 Ų55.411%0.10631%0.31CS..  trans-86.7155-179.3-63.9175-73.8177.1-0.9110.9R27 Q28 E194 P249 L250 K251R27-R253 HydrophobicContact CG-CG 4.37Å; R27-R253 PolarHBondContact O-NH1 2.95Å; Q28-R253 PolarHBondContact O-NH1 3.33Å; Q28-R253 PolarHBondContact O-NH2 3.31Å; E194-R253 WeakPolarHBondContact O-CD 3.15Å; E194-R253 PolarHBondContact O-NH1 3.38Å; E194-R253 VanDerWaalsContact O-NH1 3.14Å; P249-R253 PolarHBondContact O-NH2 3.18Å; L250-R253 HydrophobicContact CD1-CB 3.89Å; L250-R253 HydrophobicContact CG-CB 4.32Å; L250-R253 WeakPolarHBondContact O-CB 3.45Å; L250-R253 PolarHBondContact O-N 2.97Å; L250-R253 PolarHBondContact O-NE 2.91Å; K251-R253 PolarHBondContact O-N 2.74Å
254T97.5Very high97.7Very high89 Ų8958.7 Ų58.755%0.54633%0.329SS..  trans-117.1138.1171.5-58.90000108.8
255V98.8Very high97.6Very high8 Ų859.9 Ų59.95%0.04834%0.34CS..  trans-89.9129.6170.2-177.90000108.1I31 I33 A38 S39 W191 L250I31-V255 HydrophobicContact CD1-CG2 3.59Å; I33-V255 HydrophobicContact CG2-CG1 4.31Å; A38-V255 WeakPolarHBondContact CA-O 3.48Å; A38-V255 HydrophobicContact CB-CB 4.34Å; A38-V255 HydrophobicContact CB-CG1 4.2Å; S39-V255 PolarHBondContact N-O 3.01Å; W191-V255 HydrophobicContact CB-CG1 3.78Å; W191-V255 HydrophobicContact CG-CG1 4.12Å; L250-V255 HydrophobicContact CD1-CG2 4.15Å
256R98.8Very high97.5Very high74 Ų7463.7 Ų63.728%0.27936%0.361SS..EExtended strand (participates in β ladder)trans-103149.2174.3-59.3179.9-66.3149.2-1.7109.9S39 D41 L44 W191 T192S39-R256 CarbonylContact O-C 3.09Å; S39-R256 VanDerWaalsContact O-CA 3.24Å; S39-R256 WeakPolarHBondContact O-CA 3.39Å; D41-R256 HydrophobicContact CB-CB 4.2Å; D41-R256 HydrophobicContact CB-CG 4.48Å; D41-R256 WeakPolarHBondContact OD2-CD 3.35Å; D41-R256 IonicContact OD2-CZ 2.71Å; D41-R256 IonicContact OD2-NE 2.77Å; D41-R256 IonicContact OD2-NH1 3.64Å; D41-R256 PolarHBondContact OD2-NH1 2.71Å; L44-R256 HydrophobicContact CD1-CB 3.96Å; W191-R256 CarbonylContact C-O 3.34Å; W191-R256 VanDerWaalsContact CA-O 3.23Å; W191-R256 WeakPolarHBondContact CA-O 3.3Å; T192-R256 HydrophobicContact CG2-CB 3.91Å; T192-R256 PolarHBondContact N-O 2.77Å; T192-R256 PolarHBondContact O-N 3.11Å
257A98.7Very high97.5Very high4 Ų463.7 Ų63.73%0.03336%0.358CS..EExtended strand (participates in β ladder)trans-118.6139.9176.300000110.6A38 S39 Y40 D41 F259A38-A257 HydrophobicContact CB-CB 4.47Å; S39-A257 PolarHBondContact O-N 2.74Å; Y40-A257 WeakPolarHBondContact CD2-O 3.35Å; D41-A257 PolarHBondContact N-O 3.47Å; A257-F259 HydrophobicContact CB-CD1 4.28Å; A257-F259 HydrophobicContact CB-CE1 4.1Å; A257-F259 HydrophobicContact CB-CZ 4.24Å; A257-F259 PolarHBondContact O-N 2.83Å
258S98.5Very high97.4Very high24 Ų2464.6 Ų64.617%0.16836%0.36CS..SBendtrans-79.5-1.2174.272.50000113.6Y190Y190-S258 PolarHBondContact N-OG 2.92Å; Y190-S258 PolarHBondContact O-N 2.79Å; Y190-S258 PolarHBondContact O-OG 2.94Å
259F97.1Very high97.3Very high26 Ų2666.7 Ų66.711%0.11437%0.374CS..  trans-136.4159.4-172.360.5-90000110.8Y40 D189 W191 K212 A257Y40-F259 WeakPolarHBondContact CD2-O 3.47Å; D189-F259 HydrophobicContact CB-CB 4.34Å; D189-F259 HydrophobicContact CB-CD1 3.65Å; D189-F259 HydrophobicContact CB-CE1 4.29Å; D189-F259 HydrophobicContact CB-CG 4.19Å; D189-F259 WeakPolarHBondContact OD2-CB 3.18Å; W191-F259 HydrophobicContact CD2-CE1 4.36Å; W191-F259 HydrophobicContact CD2-CZ 4.23Å; W191-F259 AromaticContact CE2-CZ 3.5Å; W191-F259 VanDerWaalsContact CE2-CZ 3.5Å; W191-F259 HydrophobicContact CH2-CZ 4.43Å; W191-F259 HydrophobicContact CZ2-CE1 4.44Å; W191-F259 AromaticContact CZ2-CZ 3.61Å; W191-F259 HydrophobicContact CZ2-CZ 3.61Å; W191-F259 AromaticContact NE1-CZ 3.49Å; K212-F259 HydrophobicContact CB-CE1 4.01Å; K212-F259 HydrophobicContact CB-CZ 4.25Å; K212-F259 HydrophobicContact CD-CD1 4.18Å; K212-F259 HydrophobicContact CD-CD2 4.14Å; K212-F259 HydrophobicContact CD-CE1 3.78Å; K212-F259 HydrophobicContact CD-CE2 3.75Å; K212-F259 HydrophobicContact CD-CG 4.33Å; K212-F259 HydrophobicContact CD-CZ 3.53Å; K212-F259 HydrophobicContact CG-CE1 4.2Å; K212-F259 HydrophobicContact CG-CZ 3.96Å; K212-F259 VanDerWaalsContact NZ-CD2 3.33Å; A257-F259 HydrophobicContact CB-CD1 4.28Å; A257-F259 HydrophobicContact CB-CE1 4.1Å; A257-F259 HydrophobicContact CB-CZ 4.24Å; A257-F259 PolarHBondContact O-N 2.83Å
260Q89.1Confident97.1Very high209 Ų20965.5 Ų65.598%0.97736%0.361SS*.  trans-87.40176.2-67.8-173.6-10.900112.7Y40Y40-Q260 HydrophobicContact CD1-CG 3.68Å; Y40-Q260 HydrophobicContact CD2-CG 4.11Å; Y40-Q260 HydrophobicContact CE1-CG 3.72Å; Y40-Q260 HydrophobicContact CE2-CG 4.14Å; Y40-Q260 HydrophobicContact CG-CG 3.87Å

Retrieved 260 of 260 residues in 173.8 ms (Link to these results)