A0A087XW02_POEFO Loading...

Nuclear receptor subfamily 0 group B member 2

Transcriptional regulator that acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with which it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated transcription complex for NEUROD1. Essential component of the liver circadian clock which via its interaction with NR1D1 and RORG regulates NPAS2-mediated hepatic lipid metabolism. Regulates the circadian expression of cytochrome P450 (CYP) enzymes. Represses: NR5A2 and HNF4A to down-regulate CYP2C38, NFLI3 to up-regulate CYP2A5, BHLHE41/HNF1A axis to up-regulate CYP1A2, CYP2E1 and CYP3A11, and NR1D1 to up-regulate CYP2B10, CYP4A10 and CYP4A14.

AlphaFold DB , UniProt , Accession A0A087XW02, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 260 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32	Very low	42.8	Very low	233 Å²	233	124.6 Å²	124.6	100%	1.148	74%	0.739	S	S	*	*				0	103	0	-82.3	177.5	162	0	0	106	S3	M1-S3 PolarHBondContact O-N 3.1Å
2	D	35.4	Very low	42.2	Very low	156 Å²	156	125.7 Å²	125.7	83%	0.834	74%	0.738	S	S	*	*			trans	-76.7	103.3	-169.4	-68.1	-31.6	0	0	0	110.7	R4	D2-R4 PolarHBondContact O-N 3.49Å
3	S	42.7	Very low	42.3	Very low	86 Å²	86	129.9 Å²	129.9	60%	0.601	73%	0.734	S	S	*	*			trans	-78.4	67.8	172.2	-54.7	0	0	0	0	110.1	M1 R51	M1-S3 PolarHBondContact O-N 3.1Å; S3-R51 PolarHBondContact O-NH1 2.92Å; S3-R51 PolarHBondContact O-NH2 2.91Å
4	R	48.8	Very low	42.4	Very low	211 Å²	211	134.1 Å²	134.1	80%	0.796	75%	0.752	S	S	*	*			trans	-57	151.3	168.7	-86.3	-176.4	-177	173.2	2.5	110	D2 D6	D2-R4 PolarHBondContact O-N 3.49Å; R4-D6 PolarHBondContact O-N 3.41Å
5	C	47.6	Very low	42.4	Very low	47 Å²	47	129.8 Å²	129.8	32%	0.318	73%	0.726	S	S	.	*			trans	-67.9	124.3	166.1	-166.3	0	0	0	0	109	C7 C47	C5-C7 HydrophobicContact CB-CB 3.93Å; C5-C7 WeakPolarHBondContact CB-SG 3.29Å; C5-C7 PolarHBondContact O-N 3.43Å; C5-C7 WeakPolarHBondContact SG-CB 3.45Å; C5-C7 PolarHBondContact SG-N 3.4Å; C5-C7 VanDerWaalsContact SG-N 3.42Å; C5-C7 CovalentContact SG-SG 2.07Å; C5-C7 PolarHBondContact SG-SG 2.96Å; C5-C47 HydrophobicContact CB-CB 4.45Å; C5-C47 PolarHBondContact SG-SG 3.27Å
6	D	47.4	Very low	42.9	Very low	158 Å²	158	128.1 Å²	128.1	85%	0.845	72%	0.715	S	S	*	*			trans	-72.5	37.1	166.4	-77.1	-26.1	0	0	0	112.6	R4 S8	R4-D6 PolarHBondContact O-N 3.41Å; D6-S8 PolarHBondContact O-N 2.83Å
7	C	52.7	Low	43.8	Very low	59 Å²	59	126.3 Å²	126.3	40%	0.399	71%	0.71	S	S	.	*			trans	-81.4	9.8	177.3	-65.2	0	0	0	0	112.3	C5 C45 C47	C5-C7 HydrophobicContact CB-CB 3.93Å; C5-C7 WeakPolarHBondContact CB-SG 3.29Å; C5-C7 PolarHBondContact O-N 3.43Å; C5-C7 WeakPolarHBondContact SG-CB 3.45Å; C5-C7 PolarHBondContact SG-N 3.4Å; C5-C7 VanDerWaalsContact SG-N 3.42Å; C5-C7 CovalentContact SG-SG 2.07Å; C5-C7 PolarHBondContact SG-SG 2.96Å; C7-C45 HydrophobicContact CB-CB 3.6Å; C7-C45 PolarHBondContact SG-SG 3.14Å; C7-C47 PolarHBondContact SG-SG 3.04Å
8	S	46.3	Very low	44.4	Very low	109 Å²	109	126.4 Å²	126.4	76%	0.762	71%	0.707	S	S	*	*	S	Bend	trans	-120.8	59.2	-179.8	-55.6	0	0	0	0	110	D6	D6-S8 PolarHBondContact O-N 2.83Å
9	N	40.2	Very low	44.8	Very low	160 Å²	160	124.2 Å²	124.2	86%	0.856	69%	0.693	S	S	*	*			trans	-161.8	20	151.2	-137.5	31	0	0	0	116	G11	N9-G11 PolarHBondContact O-N 3.16Å
10	G	34.9	Very low	45.3	Very low	80 Å²	80	123.8 Å²	123.8	83%	0.825	68%	0.681	S	S	*	*			trans	-88.4	49.4	175.8	0	0	0	0	0	112.8	D12	G10-D12 VanDerWaalsContact C-N 3.25Å; G10-D12 PolarHBondContact O-N 3.2Å
11	G	42.3	Very low	45.6	Very low	72 Å²	72	122.6 Å²	122.6	74%	0.742	67%	0.674	S	S	*	*			trans	-74.9	81.3	168.5	0	0	0	0	0	109.6	N9	N9-G11 PolarHBondContact O-N 3.16Å
12	D	36.4	Very low	46.8	Very low	137 Å²	137	115.9 Å²	115.9	73%	0.733	64%	0.642	S	S	*	*	S	Bend	trans	-165.6	112.2	149.3	-108.9	-28.2	0	0	0	112.2	G10 L14	G10-D12 VanDerWaalsContact C-N 3.25Å; G10-D12 PolarHBondContact O-N 3.2Å; D12-L14 PolarHBondContact O-N 3.08Å
13	R	43.7	Very low	47.5	Very low	181 Å²	181	112.6 Å²	112.6	68%	0.683	62%	0.624	S	S	*	*			trans	36.7	85.6	141.5	-64.3	174.1	168.2	-169.5	-2.3	116.7	L15	R13-L15 HydrophobicContact CB-CD1 4.06Å; R13-L15 HydrophobicContact CB-CG 4.34Å; R13-L15 HydrophobicContact CG-CD1 3.98Å; R13-L15 PolarHBondContact O-N 2.91Å
14	L	43	Very low	47.9	Very low	189 Å²	189	111.3 Å²	111.3	99%	0.99	62%	0.615	S	S	*	*			trans	-72.4	64	144.5	-89.8	156.3	0	0	0	109.2	D12 N16	D12-L14 PolarHBondContact O-N 3.08Å; L14-N16 PolarHBondContact O-N 3.33Å
15	L	43.1	Very low	47.9	Very low	69 Å²	69	109.2 Å²	109.2	36%	0.361	61%	0.614	S	S	.	*			trans	-77.9	114.1	155.8	-76.1	156.6	0	0	0	105	R13 P17 Y20	R13-L15 HydrophobicContact CB-CD1 4.06Å; R13-L15 HydrophobicContact CB-CG 4.34Å; R13-L15 HydrophobicContact CG-CD1 3.98Å; R13-L15 PolarHBondContact O-N 2.91Å; L15-P17 WeakPolarHBondContact O-CD 3.46Å; L15-P17 VanDerWaalsContact O-N 3.11Å; L15-Y20 HydrophobicContact CB-CD2 4.33Å; L15-Y20 HydrophobicContact CD1-CD2 3.54Å; L15-Y20 HydrophobicContact CD1-CE2 4.01Å; L15-Y20 HydrophobicContact CG-CD2 4.38Å
16	N	50.4	Low	48	Very low	103 Å²	103	113.1 Å²	113.1	55%	0.551	63%	0.629	S	S	*	*			trans	-43.2	122.8	163.2	-102.1	-42.2	0	0	0	107.4	L14 I18 L19 Y20	L14-N16 PolarHBondContact O-N 3.33Å; N16-I18 PolarHBondContact O-N 3.15Å; N16-L19 HydrophobicContact CB-CB 3.96Å; N16-L19 HydrophobicContact CB-CD1 3.85Å; N16-L19 HydrophobicContact CB-CG 4.33Å; N16-L19 WeakPolarHBondContact O-CA 3.29Å; N16-L19 PolarHBondContact O-N 3.19Å; N16-Y20 PolarHBondContact O-N 3.44Å
17	P	56.9	Low	48	Very low	97 Å²	97	112.4 Å²	112.4	63%	0.63	63%	0.625	S	S	*	*	H	α-helix	trans	-57.9	-24.3	-173.8	-1.2	-3.5	0	0	0	112.5	L15 N21	L15-P17 WeakPolarHBondContact O-CD 3.46Å; L15-P17 VanDerWaalsContact O-N 3.11Å; P17-N21 PolarHBondContact O-N 3.13Å
18	I	55	Low	47.6	Very low	128 Å²	128	119.7 Å²	119.7	66%	0.656	65%	0.65	S	S	*	*	H	α-helix	trans	-70.6	-44.7	173.3	-58.5	170.5	0	0	0	111.3	N16 I22	N16-I18 PolarHBondContact O-N 3.15Å; I18-I22 HydrophobicContact CG2-CD1 3.94Å; I18-I22 WeakPolarHBondContact O-CD1 3.37Å; I18-I22 VanDerWaalsContact O-CG1 3.24Å; I18-I22 WeakPolarHBondContact O-CG1 3.33Å; I18-I22 PolarHBondContact O-N 3.41Å
19	L	52.2	Low	47.1	Very low	85 Å²	85	118.1 Å²	118.1	45%	0.445	65%	0.651	S	S	.	*	H	α-helix	trans	-69.4	-36	178.6	-91.8	156.1	0	0	0	112.2	N16 I22 L23	N16-L19 HydrophobicContact CB-CB 3.96Å; N16-L19 HydrophobicContact CB-CD1 3.85Å; N16-L19 HydrophobicContact CB-CG 4.33Å; N16-L19 WeakPolarHBondContact O-CA 3.29Å; N16-L19 PolarHBondContact O-N 3.19Å; L19-I22 PolarHBondContact O-N 3.43Å; L19-L23 HydrophobicContact CD2-CD1 4.44Å; L19-L23 WeakPolarHBondContact O-CB 3.38Å; L19-L23 VanDerWaalsContact O-CG 3.3Å; L19-L23 WeakPolarHBondContact O-CG 3.12Å; L19-L23 PolarHBondContact O-N 3.17Å
20	Y	54.2	Low	46.7	Very low	115 Å²	115	114.2 Å²	114.2	45%	0.451	65%	0.649	S	S	.	*	H	α-helix	trans	-62.1	-44.1	176.8	-171.2	-106.7	0	0	0	112.2	L15 N16 I22 L23 S24	L15-Y20 HydrophobicContact CB-CD2 4.33Å; L15-Y20 HydrophobicContact CD1-CD2 3.54Å; L15-Y20 HydrophobicContact CD1-CE2 4.01Å; L15-Y20 HydrophobicContact CG-CD2 4.38Å; N16-Y20 PolarHBondContact O-N 3.44Å; Y20-I22 VanDerWaalsContact C-N 3.34Å; Y20-I22 PolarHBondContact O-N 3.23Å; Y20-L23 PolarHBondContact O-N 3.14Å; Y20-S24 VanDerWaalsContact O-CB 3.24Å; Y20-S24 WeakPolarHBondContact O-CB 3.3Å; Y20-S24 PolarHBondContact O-N 3.29Å; Y20-S24 PolarHBondContact O-OG 3.18Å
21	N	53.3	Low	47	Very low	99 Å²	99	116.3 Å²	116.3	53%	0.529	65%	0.648	S	S	.	*	H	α-helix	trans	-71.9	-25.7	178.8	-93.9	-37.6	0	0	0	113.9	P17 Q25	P17-N21 PolarHBondContact O-N 3.13Å; N21-Q25 WeakPolarHBondContact O-CG 3.49Å
22	I	56.8	Low	46.5	Very low	92 Å²	92	118.8 Å²	118.8	47%	0.472	65%	0.654	S	S	.	*	H	α-helix	trans	-76.1	-43.1	175.5	-68.6	166.3	0	0	0	110.2	I18 L19 Y20 M26	I18-I22 HydrophobicContact CG2-CD1 3.94Å; I18-I22 WeakPolarHBondContact O-CD1 3.37Å; I18-I22 VanDerWaalsContact O-CG1 3.24Å; I18-I22 WeakPolarHBondContact O-CG1 3.33Å; I18-I22 PolarHBondContact O-N 3.41Å; L19-I22 PolarHBondContact O-N 3.43Å; Y20-I22 VanDerWaalsContact C-N 3.34Å; Y20-I22 PolarHBondContact O-N 3.23Å; I22-M26 HydrophobicContact CG2-CE 4.1Å; I22-M26 WeakPolarHBondContact O-CE 3.2Å
23	L	48.7	Very low	46.7	Very low	87 Å²	87	121.1 Å²	121.1	46%	0.455	66%	0.66	S	S	.	*	H	α-helix	trans	-76.1	-34.2	-178.5	-66	168.2	0	0	0	112.2	L19 Y20 Q25 M26	L19-L23 HydrophobicContact CD2-CD1 4.44Å; L19-L23 WeakPolarHBondContact O-CB 3.38Å; L19-L23 VanDerWaalsContact O-CG 3.3Å; L19-L23 WeakPolarHBondContact O-CG 3.12Å; L19-L23 PolarHBondContact O-N 3.17Å; Y20-L23 PolarHBondContact O-N 3.14Å; L23-Q25 PolarHBondContact O-N 3.21Å; L23-M26 HydrophobicContact CD2-CE 4.3Å; L23-M26 PolarHBondContact O-N 3.25Å; L23-M26 VanDerWaalsContact O-N 3.14Å
24	S	52.5	Low	46.1	Very low	59 Å²	59	119.4 Å²	119.4	41%	0.413	67%	0.665	S	S	.	*	T	Hydrogen-bonded Turn	trans	-70.5	-12.6	178.4	76.2	0	0	0	0	114.3	Y20	Y20-S24 VanDerWaalsContact O-CB 3.24Å; Y20-S24 WeakPolarHBondContact O-CB 3.3Å; Y20-S24 PolarHBondContact O-N 3.29Å; Y20-S24 PolarHBondContact O-OG 3.18Å
25	Q	47.5	Very low	45.9	Very low	168 Å²	168	116.5 Å²	116.5	79%	0.785	66%	0.655	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.8	-13.2	173.7	-74.2	-171.1	50.5	0	0	113.1	N21 L23	N21-Q25 WeakPolarHBondContact O-CG 3.49Å; L23-Q25 PolarHBondContact O-N 3.21Å
26	M	51.3	Low	45.5	Very low	129 Å²	129	121.7 Å²	121.7	64%	0.635	68%	0.675	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.8	-25.5	-179.6	-80.5	-178.3	-75.6	0	0	114	I22 L23 K28	I22-M26 HydrophobicContact CG2-CE 4.1Å; I22-M26 WeakPolarHBondContact O-CE 3.2Å; L23-M26 HydrophobicContact CD2-CE 4.3Å; L23-M26 PolarHBondContact O-N 3.25Å; L23-M26 VanDerWaalsContact O-N 3.14Å; M26-K28 PolarHBondContact O-N 3.48Å
27	D	46.2	Very low	44.6	Very low	142 Å²	142	125.3 Å²	125.3	76%	0.759	69%	0.688	S	S	*	*			trans	-103.5	74.3	-176.8	-73.8	-26.9	0	0	0	113.1
28	K	45.2	Very low	43.6	Very low	212 Å²	212	128.9 Å²	128.9	92%	0.922	70%	0.696	S	S	*	*			trans	-111.1	83	151.8	-78.5	-166.4	177.6	-177.5	0	108.8	M26	M26-K28 PolarHBondContact O-N 3.48Å
29	G	35.2	Very low	42.5	Very low	76 Å²	76	128.1 Å²	128.1	78%	0.784	70%	0.703	S	S	*	*	S	Bend	trans	-178.6	90.1	172.8	0	0	0	0	0	115.5
30	G	32.5	Very low	41.8	Very low	78 Å²	78	129.4 Å²	129.4	80%	0.804	72%	0.718	S	S	*	*			trans	93.6	137.8	150.7	0	0	0	0	0	118
31	P	39.7	Very low	41	Very low	124 Å²	124	127.4 Å²	127.4	81%	0.805	73%	0.726	S	S	*	*			trans	-98.3	145.8	179.4	36.9	-29.2	0	0	0	112.1
32	S	33	Very low	40.5	Very low	124 Å²	124	128.8 Å²	128.8	87%	0.867	74%	0.74	S	S	*	*			trans	-153	126.3	156.3	-65.5	0	0	0	0	109.6
33	Q	40.8	Very low	40	Very low	186 Å²	186	133.3 Å²	133.3	87%	0.869	76%	0.759	S	S	*	*			trans	-61.1	138.8	170.6	-76.9	168.4	-31.5	0	0	109.9
34	D	30.8	Very low	39.8	Very low	146 Å²	146	140 Å²	140	78%	0.781	78%	0.778	S	S	*	*			trans	-146.9	136.9	149	-102.1	-30.9	0	0	0	112	F36	D34-F36 HydrophobicContact CB-CE2 4.31Å
35	T	39	Very low	39.9	Very low	128 Å²	128	139.1 Å²	139.1	79%	0.785	77%	0.771	S	S	*	*			trans	-87.5	115.6	-172.7	-55.7	0	0	0	0	108.4
36	F	33.3	Very low	40.3	Very low	177 Å²	177	136.5 Å²	136.5	78%	0.776	76%	0.763	S	S	*	*			trans	-116.6	113.2	172.4	-83.6	-82.3	0	0	0	111.3	D34 H38	D34-F36 HydrophobicContact CB-CE2 4.31Å; F36-H38 PolarHBondContact O-N 3.16Å
37	H	33.1	Very low	40.5	Very low	180 Å²	180	131.6 Å²	131.6	83%	0.833	74%	0.741	S	S	*	*			trans	-59.1	114.2	164.8	-87.4	-83.4	0	0	0	109.6	S39	H37-S39 PolarHBondContact O-N 3.35Å
38	H	34.6	Very low	40.8	Very low	171 Å²	171	131.1 Å²	131.1	79%	0.792	73%	0.734	S	S	*	*			trans	-86.9	104	178.7	-128.4	-98.2	0	0	0	110	F36 S40	F36-H38 PolarHBondContact O-N 3.16Å; H38-S40 PolarHBondContact O-N 2.8Å; H38-S40 VanDerWaalsContact O-N 3.15Å
39	S	33.1	Very low	41.2	Very low	113 Å²	113	125.6 Å²	125.6	79%	0.79	72%	0.718	S	S	*	*			trans	-69.3	100	163.6	-38.5	0	0	0	0	107.9	H37 A41	H37-S39 PolarHBondContact O-N 3.35Å; S39-A41 PolarHBondContact O-N 3.16Å
40	S	36.8	Very low	42.4	Very low	111 Å²	111	131.6 Å²	131.6	78%	0.776	72%	0.717	S	S	*	*			trans	-69.1	95.8	175.8	-75	0	0	0	0	110.7	H38	H38-S40 PolarHBondContact O-N 2.8Å; H38-S40 VanDerWaalsContact O-N 3.15Å
41	A	37.6	Very low	44.5	Very low	74 Å²	74	131.8 Å²	131.8	61%	0.612	69%	0.693	S	S	*	*			trans	-65	132.9	158.3	0	0	0	0	0	108.5	S39 H43	S39-A41 PolarHBondContact O-N 3.16Å; A41-H43 PolarHBondContact O-N 3Å; A41-H43 VanDerWaalsContact O-N 3.11Å
42	P	43	Very low	46.8	Very low	127 Å²	127	127 Å²	127	83%	0.825	66%	0.662	S	S	*	*			trans	-65.2	116.5	179.6	23.8	-30.3	0	0	0	109.9	R44	P42-R44 PolarHBondContact O-N 3Å; P42-R44 VanDerWaalsContact O-N 3.08Å
43	H	45.9	Very low	49.7	Very low	187 Å²	187	121.4 Å²	121.4	87%	0.866	62%	0.622	S	S	*	*			trans	-64.3	107.5	171.9	-69.8	-59.1	0	0	0	109.4	A41 C45	A41-H43 PolarHBondContact O-N 3Å; A41-H43 VanDerWaalsContact O-N 3.11Å; H43-C45 PolarHBondContact O-N 2.83Å; H43-C45 VanDerWaalsContact O-N 3.12Å
44	R	45.8	Very low	52.2	Low	229 Å²	229	115 Å²	115	86%	0.864	60%	0.598	S	S	*	*			trans	-69.9	103.4	166.9	-97.8	-176.8	-178.7	-125.9	1	108.7	P42	P42-R44 PolarHBondContact O-N 3Å; P42-R44 VanDerWaalsContact O-N 3.08Å
45	C	53.8	Low	55.3	Low	40 Å²	40	108.6 Å²	108.6	27%	0.27	56%	0.563	S	S	.	*			trans	-74.9	137.4	169.6	161.6	0	0	0	0	111	C7 H43 C47 E48	C7-C45 HydrophobicContact CB-CB 3.6Å; C7-C45 PolarHBondContact SG-SG 3.14Å; H43-C45 PolarHBondContact O-N 2.83Å; H43-C45 VanDerWaalsContact O-N 3.12Å; C45-C47 HydrophobicContact CB-CB 4.48Å; C45-C47 WeakPolarHBondContact CB-SG 3.27Å; C45-C47 PolarHBondContact O-N 2.75Å; C45-C47 WeakPolarHBondContact SG-CB 2.74Å; C45-C47 PolarHBondContact SG-N 3.23Å; C45-C47 CovalentContact SG-SG 2.06Å; C45-C47 PolarHBondContact SG-SG 3.01Å; C45-E48 PolarHBondContact O-N 3Å
46	N	55.2	Low	58	Low	113 Å²	113	106.3 Å²	106.3	60%	0.604	55%	0.549	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.4	1.9	177.7	-126.1	13.5	0	0	0	114.8	V49	N46-V49 PolarHBondContact O-N 2.76Å
47	C	56.5	Low	61	Low	26 Å²	26	103.1 Å²	103.1	18%	0.176	53%	0.532	C	S	.	.	H	α-helix	trans	-68.4	-34.1	173.4	44.7	0	0	0	0	112.5	C5 C7 C45 V49 R50 R51	C5-C47 HydrophobicContact CB-CB 4.45Å; C5-C47 PolarHBondContact SG-SG 3.27Å; C7-C47 PolarHBondContact SG-SG 3.04Å; C45-C47 HydrophobicContact CB-CB 4.48Å; C45-C47 WeakPolarHBondContact CB-SG 3.27Å; C45-C47 PolarHBondContact O-N 2.75Å; C45-C47 WeakPolarHBondContact SG-CB 2.74Å; C45-C47 PolarHBondContact SG-N 3.23Å; C45-C47 CovalentContact SG-SG 2.06Å; C45-C47 PolarHBondContact SG-SG 3.01Å; C47-V49 PolarHBondContact O-N 3.12Å; C47-R50 PolarHBondContact O-N 3.14Å; C47-R50 VanDerWaalsContact O-N 3.15Å; C47-R51 PolarHBondContact O-N 2.77Å; C47-R51 VanDerWaalsContact O-N 3.16Å
48	E	51.1	Low	63.9	Low	131 Å²	131	97.2 Å²	97.2	61%	0.612	51%	0.51	S	S	*	.	H	α-helix	trans	-65.1	-30.6	176.1	-66.9	-174.6	167.1	0	0	111.8	C45 R50	C45-E48 PolarHBondContact O-N 3Å; E48-R50 VanDerWaalsContact C-N 3.3Å
49	V	53.7	Low	66.7	Low	97 Å²	97	94 Å²	94	59%	0.588	51%	0.507	S	S	*	.	H	α-helix	trans	-75.6	-21.8	177.7	-174.3	0	0	0	0	111.6	N46 C47	N46-V49 PolarHBondContact O-N 2.76Å; C47-V49 PolarHBondContact O-N 3.12Å
50	R	61.3	Low	69.8	Low	202 Å²	202	93.4 Å²	93.4	76%	0.762	49%	0.491	S	S	*	.	H	α-helix	trans	-101.1	-7.8	-177.3	-69.4	-177.1	174.6	-175.6	-1.9	114.3	C47 E48 T52	C47-R50 PolarHBondContact O-N 3.14Å; C47-R50 VanDerWaalsContact O-N 3.15Å; E48-R50 VanDerWaalsContact C-N 3.3Å; R50-T52 PolarHBondContact O-N 2.96Å
51	R	76.6	Confident	72.7	Confident	82 Å²	82	88.2 Å²	88.2	31%	0.309	46%	0.455	S	S	.	.			trans	-83	109.8	176.4	-79.2	-171.5	-171.5	-171.7	3.9	109.9	S3 C47 D117	S3-R51 PolarHBondContact O-NH1 2.92Å; S3-R51 PolarHBondContact O-NH2 2.91Å; C47-R51 PolarHBondContact O-N 2.77Å; C47-R51 VanDerWaalsContact O-N 3.16Å; R51-D117 IonicContact NH1-OD2 2.74Å
52	T	88.8	Confident	75.5	Confident	24 Å²	24	84.8 Å²	84.8	15%	0.147	43%	0.427	C	S	.	.	B	Isolated β-bridge	trans	-98	152	178.3	62	0	0	0	0	109.2	R50 V118 Q141 P142	R50-T52 PolarHBondContact O-N 2.96Å; T52-V118 WeakPolarHBondContact O-CB 3.41Å; T52-V118 PolarHBondContact O-N 3.39Å; T52-Q141 HydrophobicContact CG2-CB 3.46Å; T52-Q141 VanDerWaalsContact CG2-CB 3.46Å; T52-Q141 HydrophobicContact CG2-CG 4.3Å; T52-Q141 VanDerWaalsContact CG2-OE1 3.22Å; T52-Q141 PolarHBondContact OG1-OE1 3.22Å; T52-P142 CarbonylContact C-O 3.57Å; T52-P142 WeakPolarHBondContact CA-O 3.37Å
53	V	92.5	Very high	78.1	Confident	5 Å²	5	86.7 Å²	86.7	3%	0.03	42%	0.422	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.1	155	-172	-62.2	0	0	0	0	111.9	V115 T116 P142 M144 V147	V53-V115 HydrophobicContact CB-CB 4.2Å; V53-V115 HydrophobicContact CB-CG2 4.44Å; V53-V115 HydrophobicContact CG2-CB 4.24Å; V53-V115 HydrophobicContact CG2-CG1 4.48Å; V53-V115 HydrophobicContact CG2-CG2 4.34Å; V53-T116 VanDerWaalsContact CA-O 3.25Å; V53-T116 WeakPolarHBondContact CA-O 3.42Å; V53-T116 WeakPolarHBondContact CB-O 3.47Å; V53-P142 HydrophobicContact CG2-CB 4.21Å; V53-P142 PolarHBondContact N-O 3.33Å; V53-M144 HydrophobicContact CB-SD 4.17Å; V53-M144 HydrophobicContact CG1-CB 4.45Å; V53-M144 HydrophobicContact CG1-CG 3.44Å; V53-M144 VanDerWaalsContact CG1-CG 3.44Å; V53-M144 HydrophobicContact CG1-SD 3.28Å; V53-M144 WeakPolarHBondContact CG1-SD 3.07Å; V53-M144 HydrophobicContact CG2-SD 4.27Å; V53-V147 HydrophobicContact CG2-CG2 3.67Å
54	C	93.6	Very high	80.6	Confident	53 Å²	53	81.9 Å²	81.9	36%	0.358	40%	0.4	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.5	162.5	174.7	64.6	0	0	0	0	110.6	V115 T116 V118	C54-V115 CarbonylContact O-C 3.55Å; C54-V115 WeakPolarHBondContact O-CA 3.36Å; C54-V115 WeakPolarHBondContact O-CB 3.5Å; C54-T116 PolarHBondContact N-O 3.08Å; C54-T116 PolarHBondContact O-N 3.04Å; C54-V118 HydrophobicContact CB-CG2 3.71Å
55	L	96.1	Very high	83.1	Confident	10 Å²	10	71 Å²	71	5%	0.052	36%	0.359	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-65	138.2	175.4	-65.9	170.2	0	0	0	110.7	P58 V61 F113 D114 V115 L236 F237	L55-P58 HydrophobicContact CB-CB 4.17Å; L55-P58 WeakPolarHBondContact O-CD 3.46Å; L55-V61 HydrophobicContact CD1-CB 4.14Å; L55-V61 HydrophobicContact CD1-CG1 3.9Å; L55-V61 HydrophobicContact CD2-CG1 4Å; L55-F113 HydrophobicContact CD2-CB 4.12Å; L55-F113 HydrophobicContact CD2-CD2 3.68Å; L55-F113 HydrophobicContact CD2-CG 4.17Å; L55-D114 CarbonylContact C-O 3.56Å; L55-D114 WeakPolarHBondContact CA-O 3.49Å; L55-V115 HydrophobicContact CD2-CG1 4.25Å; L55-L236 VanDerWaalsContact CD1-O 3.28Å; L55-L236 WeakPolarHBondContact CD1-O 3.42Å; L55-L236 HydrophobicContact CD2-CD1 3.93Å; L55-L236 HydrophobicContact CD2-CG 4.14Å; L55-L236 HydrophobicContact CG-CD1 3.89Å; L55-L236 HydrophobicContact CG-CG 4.29Å; L55-F237 HydrophobicContact CD1-CD1 4.39Å
56	V	96.1	Very high	85.2	Confident	80 Å²	80	70.9 Å²	70.9	49%	0.485	36%	0.358	S	S	.	.	S	Bend	trans	-68.7	-39.5	173.9	175.1	0	0	0	0	110.9	P58 D114 T116	V56-P58 VanDerWaalsContact C-CD 3.45Å; V56-P58 WeakPolarHBondContact O-CD 3.37Å; V56-D114 HydrophobicContact CB-CB 4.05Å; V56-D114 HydrophobicContact CG2-CB 3.79Å; V56-D114 PolarHBondContact N-O 3.03Å; V56-T116 HydrophobicContact CG2-CG2 4.3Å
57	R	95.4	Very high	87.3	Confident	110 Å²	110	67.9 Å²	67.9	42%	0.415	35%	0.349	S	S	.	.	S	Bend	trans	-119.8	68.3	179.1	-65.2	-177.9	-67.2	138.4	-0.2	110.5	S59 E60 V61	R57-S59 PolarHBondContact O-N 2.91Å; R57-E60 HydrophobicContact CB-CB 4.47Å; R57-E60 WeakPolarHBondContact CD-OE2 3.43Å; R57-E60 IonicContact CZ-OE2 2.72Å; R57-E60 IonicContact NE-OE2 2.64Å; R57-E60 IonicContact NH1-OE2 3.94Å; R57-E60 PolarHBondContact NH1-OE2 3.44Å; R57-E60 PolarHBondContact O-N 3.03Å; R57-V61 HydrophobicContact CB-CG2 4.42Å; R57-V61 WeakPolarHBondContact O-CB 3.38Å; R57-V61 WeakPolarHBondContact O-CG2 3.38Å; R57-V61 PolarHBondContact O-N 3.01Å; R57-V61 VanDerWaalsContact O-N 3.11Å
58	P	94.2	Very high	89.3	Confident	57 Å²	57	66.9 Å²	66.9	37%	0.37	34%	0.342	S	S	.	.	H	α-helix	trans	-61.5	-41.7	-171.3	23.1	-31.5	0	0	0	112.1	L55 V56 E60 C62	L55-P58 HydrophobicContact CB-CB 4.17Å; L55-P58 WeakPolarHBondContact O-CD 3.46Å; V56-P58 VanDerWaalsContact C-CD 3.45Å; V56-P58 WeakPolarHBondContact O-CD 3.37Å; P58-E60 PolarHBondContact O-N 3.47Å; P58-C62 WeakPolarHBondContact O-CB 3.37Å; P58-C62 PolarHBondContact O-N 3.36Å; P58-C62 PolarHBondContact O-SG 3.46Å
59	S	94.6	Very high	91.5	Very high	104 Å²	104	61 Å²	61	73%	0.727	32%	0.315	S	S	*	.	H	α-helix	trans	-61.3	-43.8	-177.7	-177.2	0	0	0	0	113.5	R57 K63	R57-S59 PolarHBondContact O-N 2.91Å; S59-K63 WeakPolarHBondContact O-CB 3.4Å; S59-K63 PolarHBondContact O-N 3.48Å
60	E	96.6	Very high	93.6	Very high	99 Å²	99	60.4 Å²	60.4	46%	0.463	31%	0.311	S	S	.	.	H	α-helix	trans	-73.3	-52.5	-178.3	-67.4	167.5	-149.5	0	0	111.1	R57 P58 C62 K63 E64	R57-E60 HydrophobicContact CB-CB 4.47Å; R57-E60 WeakPolarHBondContact CD-OE2 3.43Å; R57-E60 IonicContact CZ-OE2 2.72Å; R57-E60 IonicContact NE-OE2 2.64Å; R57-E60 IonicContact NH1-OE2 3.94Å; R57-E60 PolarHBondContact NH1-OE2 3.44Å; R57-E60 PolarHBondContact O-N 3.03Å; P58-E60 PolarHBondContact O-N 3.47Å; E60-C62 PolarHBondContact O-N 3.14Å; E60-K63 WeakPolarHBondContact O-CB 3.31Å; E60-K63 PolarHBondContact O-N 2.88Å; E60-E64 PolarHBondContact O-N 3.21Å
61	V	97.7	Very high	95.3	Very high	2 Å²	2	55.6 Å²	55.6	1%	0.012	30%	0.296	C	S	.	.	H	α-helix	trans	-64.9	-41.6	-176.7	175.4	0	0	0	0	111.1	L55 R57 K63 E64 A65 F113 F237	L55-V61 HydrophobicContact CD1-CB 4.14Å; L55-V61 HydrophobicContact CD1-CG1 3.9Å; L55-V61 HydrophobicContact CD2-CG1 4Å; R57-V61 HydrophobicContact CB-CG2 4.42Å; R57-V61 WeakPolarHBondContact O-CB 3.38Å; R57-V61 WeakPolarHBondContact O-CG2 3.38Å; R57-V61 PolarHBondContact O-N 3.01Å; R57-V61 VanDerWaalsContact O-N 3.11Å; V61-K63 VanDerWaalsContact C-N 3.31Å; V61-K63 PolarHBondContact O-N 3Å; V61-E64 PolarHBondContact O-N 2.89Å; V61-A65 VanDerWaalsContact O-CB 3.27Å; V61-A65 WeakPolarHBondContact O-CB 3.36Å; V61-A65 PolarHBondContact O-N 3.47Å; V61-F113 HydrophobicContact CB-CB 4.43Å; V61-F113 HydrophobicContact CG1-CB 3.68Å; V61-F113 HydrophobicContact CG1-CG 4.39Å; V61-F113 HydrophobicContact CG2-CB 3.83Å; V61-F237 HydrophobicContact CG1-CD1 3.93Å; V61-F237 HydrophobicContact CG1-CE1 3.79Å
62	C	97.8	Very high	96.3	Very high	3 Å²	3	52 Å²	52	2%	0.02	28%	0.283	C	S	.	.	H	α-helix	trans	-65.7	-34.8	177.4	-67.7	0	0	0	0	111.9	P58 E60 A65 S66 F237 V241	P58-C62 WeakPolarHBondContact O-CB 3.37Å; P58-C62 PolarHBondContact O-N 3.36Å; P58-C62 PolarHBondContact O-SG 3.46Å; E60-C62 PolarHBondContact O-N 3.14Å; C62-A65 PolarHBondContact O-N 3.23Å; C62-S66 WeakPolarHBondContact O-CB 3.44Å; C62-S66 PolarHBondContact O-N 3.4Å; C62-S66 PolarHBondContact O-OG 3.3Å; C62-F237 PolarHBondContact SG-O 2.88Å; C62-V241 HydrophobicContact CB-CG2 3.49Å; C62-V241 VanDerWaalsContact CB-CG2 3.49Å
63	K	97.8	Very high	96.6	Very high	166 Å²	166	51.1 Å²	51.1	72%	0.722	28%	0.278	S	S	*	.	H	α-helix	trans	-65	-45.2	175.4	-178.7	-176.5	177.2	-175	0	111.6	S59 E60 V61 S66 A67	S59-K63 WeakPolarHBondContact O-CB 3.4Å; S59-K63 PolarHBondContact O-N 3.48Å; E60-K63 WeakPolarHBondContact O-CB 3.31Å; E60-K63 PolarHBondContact O-N 2.88Å; V61-K63 VanDerWaalsContact C-N 3.31Å; V61-K63 PolarHBondContact O-N 3Å; K63-S66 PolarHBondContact O-N 2.94Å; K63-A67 PolarHBondContact O-N 3.43Å
64	E	98.3	Very high	96.8	Very high	87 Å²	87	55.3 Å²	55.3	41%	0.407	30%	0.297	S	S	.	.	H	α-helix	trans	-62.6	-46.1	175	-71	174.7	-162.4	0	0	111.2	E60 V61 S66 A67 V68 V111	E60-E64 PolarHBondContact O-N 3.21Å; V61-E64 PolarHBondContact O-N 2.89Å; E64-S66 PolarHBondContact O-N 3.44Å; E64-A67 WeakPolarHBondContact O-CB 3.32Å; E64-A67 PolarHBondContact O-N 2.97Å; E64-A67 VanDerWaalsContact O-N 3.14Å; E64-V68 WeakPolarHBondContact O-CG2 3.45Å; E64-V68 PolarHBondContact O-N 3Å; E64-V111 HydrophobicContact CB-CG1 4.38Å; E64-V111 HydrophobicContact CB-CG2 4.3Å
65	A	98.3	Very high	96.9	Very high	0 Å²	0	55.5 Å²	55.5	0%	0	29%	0.291	C	S	.	.	H	α-helix	trans	-58.3	-44.3	174.7	0	0	0	0	0	112.3	V61 C62 A67 V68 L69 F102 F237 F238	V61-A65 VanDerWaalsContact O-CB 3.27Å; V61-A65 WeakPolarHBondContact O-CB 3.36Å; V61-A65 PolarHBondContact O-N 3.47Å; C62-A65 PolarHBondContact O-N 3.23Å; A65-A67 VanDerWaalsContact C-N 3.33Å; A65-A67 PolarHBondContact O-N 3.13Å; A65-V68 WeakPolarHBondContact O-CB 3.39Å; A65-V68 PolarHBondContact O-N 3.01Å; A65-L69 PolarHBondContact O-N 3.41Å; A65-F102 HydrophobicContact CB-CE2 4.13Å; A65-F102 HydrophobicContact CB-CZ 3.78Å; A65-F102 WeakPolarHBondContact O-CE2 3.32Å; A65-F237 HydrophobicContact CB-CB 3.97Å; A65-F237 HydrophobicContact CB-CD1 3.88Å; A65-F237 HydrophobicContact CB-CG 4.18Å; A65-F238 HydrophobicContact CB-CE1 4.42Å; A65-F238 HydrophobicContact CB-CZ 4.43Å
66	S	98.1	Very high	96.9	Very high	38 Å²	38	55 Å²	55	27%	0.266	29%	0.289	S	S	.	.	H	α-helix	trans	-61	-41.2	175	-66.1	0	0	0	0	112.1	C62 K63 E64 V68 L69 V70	C62-S66 WeakPolarHBondContact O-CB 3.44Å; C62-S66 PolarHBondContact O-N 3.4Å; C62-S66 PolarHBondContact O-OG 3.3Å; K63-S66 PolarHBondContact O-N 2.94Å; E64-S66 PolarHBondContact O-N 3.44Å; S66-V68 VanDerWaalsContact C-N 3.35Å; S66-V68 PolarHBondContact O-N 3.45Å; S66-L69 PolarHBondContact O-N 3.27Å; S66-V70 WeakPolarHBondContact O-CG2 3.17Å; S66-V70 PolarHBondContact O-N 2.88Å
67	A	98.3	Very high	96.8	Very high	50 Å²	50	54.8 Å²	54.8	41%	0.413	28%	0.28	S	S	.	.	H	α-helix	trans	-62.9	-41.6	175.6	0	0	0	0	0	111.9	K63 E64 A65 V70 K71	K63-A67 PolarHBondContact O-N 3.43Å; E64-A67 WeakPolarHBondContact O-CB 3.32Å; E64-A67 PolarHBondContact O-N 2.97Å; E64-A67 VanDerWaalsContact O-N 3.14Å; A65-A67 VanDerWaalsContact C-N 3.33Å; A65-A67 PolarHBondContact O-N 3.13Å; A67-V70 PolarHBondContact O-N 3.18Å; A67-K71 WeakPolarHBondContact O-CG 3.31Å; A67-K71 PolarHBondContact O-N 2.87Å
68	V	98.5	Very high	96.8	Very high	5 Å²	5	52.9 Å²	52.9	3%	0.03	28%	0.278	C	S	.	.	H	α-helix	trans	-61.1	-45	173.8	172	0	0	0	0	111.2	E64 A65 S66 V70 K71 T72 F102 G105 L106 E109 V111	E64-V68 WeakPolarHBondContact O-CG2 3.45Å; E64-V68 PolarHBondContact O-N 3Å; A65-V68 WeakPolarHBondContact O-CB 3.39Å; A65-V68 PolarHBondContact O-N 3.01Å; S66-V68 VanDerWaalsContact C-N 3.35Å; S66-V68 PolarHBondContact O-N 3.45Å; V68-V70 VanDerWaalsContact C-N 3.35Å; V68-V70 PolarHBondContact O-N 3.4Å; V68-K71 WeakPolarHBondContact O-CB 3.4Å; V68-K71 PolarHBondContact O-N 3.29Å; V68-T72 PolarHBondContact O-N 3.04Å; V68-T72 PolarHBondContact O-OG1 2.88Å; V68-F102 HydrophobicContact CB-CD2 4.4Å; V68-F102 HydrophobicContact CB-CE2 4.05Å; V68-F102 HydrophobicContact CG1-CD2 3.8Å; V68-F102 HydrophobicContact CG1-CE2 3.86Å; V68-G105 VanDerWaalsContact CG1-C 3.49Å; V68-L106 HydrophobicContact CB-CD2 4.49Å; V68-L106 HydrophobicContact CG1-CD2 4.43Å; V68-L106 HydrophobicContact CG2-CD2 4.28Å; V68-E109 HydrophobicContact CG2-CB 4.25Å; V68-E109 HydrophobicContact CG2-CG 4.07Å; V68-V111 HydrophobicContact CG2-CG2 4.2Å
69	L	97.9	Very high	96.9	Very high	8 Å²	8	52 Å²	52	4%	0.042	27%	0.27	C	S	.	.	H	α-helix	trans	-60.4	-44.9	179.4	-167.2	71.9	0	0	0	111.7	A65 S66 T72 V73 W98 F102 F238 L247 L251 M254	A65-L69 PolarHBondContact O-N 3.41Å; S66-L69 PolarHBondContact O-N 3.27Å; L69-T72 WeakPolarHBondContact O-CB 3.48Å; L69-T72 PolarHBondContact O-N 3.5Å; L69-V73 PolarHBondContact O-N 2.89Å; L69-W98 HydrophobicContact CD1-CE3 4.48Å; L69-F102 HydrophobicContact CB-CD2 4.27Å; L69-F102 HydrophobicContact CB-CE2 4.44Å; L69-F102 HydrophobicContact CD1-CB 4.48Å; L69-F102 HydrophobicContact CD1-CD2 3.91Å; L69-F102 HydrophobicContact CD1-CG 4.41Å; L69-F238 HydrophobicContact CB-CE1 3.95Å; L69-F238 HydrophobicContact CB-CZ 3.86Å; L69-F238 HydrophobicContact CD1-CE2 4.35Å; L69-F238 HydrophobicContact CD1-CZ 3.88Å; L69-F238 HydrophobicContact CD2-CD1 4.17Å; L69-F238 HydrophobicContact CD2-CE1 3.59Å; L69-F238 HydrophobicContact CD2-CE2 4.47Å; L69-F238 HydrophobicContact CD2-CZ 3.76Å; L69-F238 HydrophobicContact CG-CE1 4.24Å; L69-F238 HydrophobicContact CG-CZ 4.04Å; L69-L247 HydrophobicContact CD2-CD1 3.83Å; L69-L251 HydrophobicContact CD1-CD2 3.87Å; L69-L251 HydrophobicContact CD2-CD2 3.96Å; L69-L251 HydrophobicContact CG-CD2 3.88Å; L69-M254 HydrophobicContact CD2-CE 4.21Å
70	V	97.3	Very high	96.9	Very high	84 Å²	84	51.5 Å²	51.5	51%	0.509	26%	0.264	S	S	.	.	H	α-helix	trans	-61.8	-44.7	176.3	172.2	0	0	0	0	110.9	S66 A67 V68 T72 V73 H74 M254	S66-V70 WeakPolarHBondContact O-CG2 3.17Å; S66-V70 PolarHBondContact O-N 2.88Å; A67-V70 PolarHBondContact O-N 3.18Å; V68-V70 VanDerWaalsContact C-N 3.35Å; V68-V70 PolarHBondContact O-N 3.4Å; V70-T72 VanDerWaalsContact C-N 3.29Å; V70-T72 PolarHBondContact O-N 3.44Å; V70-V73 PolarHBondContact O-N 2.91Å; V70-H74 WeakPolarHBondContact O-CB 3.35Å; V70-H74 PolarHBondContact O-N 3.33Å; V70-M254 HydrophobicContact CG2-SD 4.49Å
71	K	97.4	Very high	96.9	Very high	101 Å²	101	47.9 Å²	47.9	44%	0.439	25%	0.25	S	S	.	.	H	α-helix	trans	-59.3	-40.1	174.5	-73.2	173.7	177.8	-177.1	0	111.6	A67 V68 H74 F75 E109	A67-K71 WeakPolarHBondContact O-CG 3.31Å; A67-K71 PolarHBondContact O-N 2.87Å; V68-K71 WeakPolarHBondContact O-CB 3.4Å; V68-K71 PolarHBondContact O-N 3.29Å; K71-H74 PolarHBondContact O-N 3.06Å; K71-F75 WeakPolarHBondContact O-CB 3.5Å; K71-F75 PolarHBondContact O-N 3Å; K71-E109 IonicContact NZ-OE1 3.6Å; K71-E109 PolarHBondContact NZ-OE1 3.26Å; K71-E109 IonicContact NZ-OE2 3.43Å; K71-E109 PolarHBondContact NZ-OE2 3.16Å
72	T	96.8	Very high	96.9	Very high	7 Å²	7	47.8 Å²	47.8	4%	0.043	25%	0.25	C	S	.	.	H	α-helix	trans	-63.3	-50.7	177.4	-70.1	0	0	0	0	112	V68 L69 V70 H74 F75 M76 L101	V68-T72 PolarHBondContact O-N 3.04Å; V68-T72 PolarHBondContact O-OG1 2.88Å; L69-T72 WeakPolarHBondContact O-CB 3.48Å; L69-T72 PolarHBondContact O-N 3.5Å; V70-T72 VanDerWaalsContact C-N 3.29Å; V70-T72 PolarHBondContact O-N 3.44Å; T72-H74 VanDerWaalsContact C-N 3.31Å; T72-H74 PolarHBondContact O-N 3.21Å; T72-F75 WeakPolarHBondContact O-CB 3.25Å; T72-F75 PolarHBondContact O-N 3.4Å; T72-M76 PolarHBondContact O-N 2.83Å; T72-M76 VanDerWaalsContact O-N 3.13Å; T72-L101 HydrophobicContact CG2-CB 3.52Å; T72-L101 HydrophobicContact CG2-CD1 4.21Å
73	V	96.4	Very high	96.7	Very high	4 Å²	4	53.5 Å²	53.5	2%	0.024	28%	0.275	C	S	.	.	H	α-helix	trans	-63	-41.8	177.4	178.3	0	0	0	0	110.8	L69 V70 F75 M76 R77 L251 M254 L255	L69-V73 PolarHBondContact O-N 2.89Å; V70-V73 PolarHBondContact O-N 2.91Å; V73-F75 VanDerWaalsContact C-N 3.33Å; V73-F75 PolarHBondContact O-N 2.96Å; V73-M76 PolarHBondContact O-N 2.91Å; V73-R77 VanDerWaalsContact O-CB 3.27Å; V73-R77 WeakPolarHBondContact O-CB 3.21Å; V73-R77 PolarHBondContact O-N 3.38Å; V73-L251 HydrophobicContact CG2-CD2 3.42Å; V73-L251 VanDerWaalsContact CG2-CD2 3.42Å; V73-M254 HydrophobicContact CG1-CB 3.87Å; V73-L255 HydrophobicContact CG1-CB 4.26Å; V73-L255 HydrophobicContact CG1-CD1 4.31Å
74	H	95.8	Very high	96.7	Very high	94 Å²	94	52.2 Å²	52.2	44%	0.435	27%	0.271	S	S	.	.	H	α-helix	trans	-60.8	-41.4	177.1	-173.6	83	0	0	0	112.4	V70 K71 T72 N78	V70-H74 WeakPolarHBondContact O-CB 3.35Å; V70-H74 PolarHBondContact O-N 3.33Å; K71-H74 PolarHBondContact O-N 3.06Å; T72-H74 VanDerWaalsContact C-N 3.31Å; T72-H74 PolarHBondContact O-N 3.21Å; H74-N78 PolarHBondContact CD2-ND2 2.92Å; H74-N78 PolarHBondContact CE1-ND2 3.1Å; H74-N78 PolarHBondContact NE2-ND2 3.48Å; H74-N78 WeakPolarHBondContact O-CB 3.48Å; H74-N78 VanDerWaalsContact O-CG 3.25Å; H74-N78 PolarHBondContact O-N 3.47Å; H74-N78 VanDerWaalsContact O-N 3.08Å; H74-N78 PolarHBondContact O-ND2 2.96Å
75	F	96.3	Very high	96.6	Very high	56 Å²	56	48.4 Å²	48.4	25%	0.246	25%	0.253	C	S	.	.	H	α-helix	trans	-58.4	-54.6	174.9	178.7	-97	0	0	0	110.8	K71 T72 V73 R77 N78 L79 K171 I175	K71-F75 WeakPolarHBondContact O-CB 3.5Å; K71-F75 PolarHBondContact O-N 3Å; T72-F75 WeakPolarHBondContact O-CB 3.25Å; T72-F75 PolarHBondContact O-N 3.4Å; V73-F75 VanDerWaalsContact C-N 3.33Å; V73-F75 PolarHBondContact O-N 2.96Å; F75-R77 PolarHBondContact O-N 2.79Å; F75-N78 PolarHBondContact O-N 3.49Å; F75-L79 HydrophobicContact CD1-CD1 4.39Å; F75-L79 HydrophobicContact CE1-CD1 3.99Å; F75-L79 HydrophobicContact CE1-CD2 4.49Å; F75-L79 HydrophobicContact CZ-CD2 4.26Å; F75-L79 WeakPolarHBondContact O-CG 3.47Å; F75-L79 PolarHBondContact O-N 3.14Å; F75-K171 HydrophobicContact CD1-CB 4.34Å; F75-K171 HydrophobicContact CD1-CD 4.35Å; F75-K171 HydrophobicContact CE1-CB 3.59Å; F75-K171 HydrophobicContact CE1-CD 4.23Å; F75-K171 HydrophobicContact CZ-CB 3.98Å; F75-K171 HydrophobicContact CZ-CD 4.46Å; F75-I175 HydrophobicContact CD1-CD1 3.76Å; F75-I175 HydrophobicContact CE1-CD1 3.52Å
76	M	95.9	Very high	96.6	Very high	0 Å²	0	50 Å²	50	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-57.2	-49.9	178.9	-65.5	-178.7	68.4	0	0	111.9	T72 V73 N78 L79 F82 L94 C97 L101 I175	T72-M76 PolarHBondContact O-N 2.83Å; T72-M76 VanDerWaalsContact O-N 3.13Å; V73-M76 PolarHBondContact O-N 2.91Å; M76-N78 PolarHBondContact O-N 3.3Å; M76-N78 VanDerWaalsContact O-N 3.15Å; M76-L79 PolarHBondContact O-N 2.95Å; M76-F82 HydrophobicContact CE-CE2 3.72Å; M76-F82 HydrophobicContact CE-CZ 3.77Å; M76-L94 HydrophobicContact CE-CB 4.36Å; M76-L94 HydrophobicContact CE-CD1 4.11Å; M76-L94 HydrophobicContact SD-CD1 3.95Å; M76-C97 WeakPolarHBondContact CE-SG 3.25Å; M76-L101 HydrophobicContact CE-CD1 4.37Å; M76-L101 HydrophobicContact CG-CD1 3.86Å; M76-L101 HydrophobicContact SD-CD1 3.48Å; M76-L101 WeakPolarHBondContact SD-CD1 3.4Å; M76-I175 HydrophobicContact CE-CG1 4.44Å; M76-I175 HydrophobicContact CE-CG2 4.43Å; M76-I175 HydrophobicContact CG-CD1 3.82Å; M76-I175 HydrophobicContact CG-CG1 4.13Å
77	R	93.6	Very high	96.5	Very high	76 Å²	76	52.7 Å²	52.7	29%	0.287	28%	0.28	S	S	.	.	H	α-helix	trans	-59.9	-27.9	-178.2	-167.6	175.3	68.4	-171.9	3.9	112.7	V73 F75 K83 M254 L255	V73-R77 VanDerWaalsContact O-CB 3.27Å; V73-R77 WeakPolarHBondContact O-CB 3.21Å; V73-R77 PolarHBondContact O-N 3.38Å; F75-R77 PolarHBondContact O-N 2.79Å; R77-K83 WeakPolarHBondContact O-CE 3.36Å; R77-M254 PolarHBondContact NH1-O 3.44Å; R77-M254 VanDerWaalsContact NH1-O 3.13Å; R77-L255 HydrophobicContact CB-CD1 3.93Å; R77-L255 VanDerWaalsContact CD-O 3.3Å; R77-L255 WeakPolarHBondContact CD-O 3.35Å; R77-L255 HydrophobicContact CG-CD1 4.33Å
78	N	94.6	Very high	96.4	Very high	70 Å²	70	52.3 Å²	52.3	37%	0.374	28%	0.281	S	S	.	.	H	α-helix	trans	-92.3	-6.7	-176.9	-73.5	-22.7	0	0	0	114.5	H74 F75 M76 P80	H74-N78 PolarHBondContact CD2-ND2 2.92Å; H74-N78 PolarHBondContact CE1-ND2 3.1Å; H74-N78 PolarHBondContact NE2-ND2 3.48Å; H74-N78 WeakPolarHBondContact O-CB 3.48Å; H74-N78 VanDerWaalsContact O-CG 3.25Å; H74-N78 PolarHBondContact O-N 3.47Å; H74-N78 VanDerWaalsContact O-N 3.08Å; H74-N78 PolarHBondContact O-ND2 2.96Å; F75-N78 PolarHBondContact O-N 3.49Å; M76-N78 PolarHBondContact O-N 3.3Å; M76-N78 VanDerWaalsContact O-N 3.15Å; N78-P80 VanDerWaalsContact O-CD 3.29Å; N78-P80 WeakPolarHBondContact O-CD 3.46Å
79	L	96.4	Very high	96.4	Very high	39 Å²	39	52.2 Å²	52.2	20%	0.204	28%	0.28	C	S	.	.			trans	-69.8	119.4	175.8	-68.2	173.8	0	0	0	110.3	F75 M76 A81 F82 K83 I175 F176	F75-L79 HydrophobicContact CD1-CD1 4.39Å; F75-L79 HydrophobicContact CE1-CD1 3.99Å; F75-L79 HydrophobicContact CE1-CD2 4.49Å; F75-L79 HydrophobicContact CZ-CD2 4.26Å; F75-L79 WeakPolarHBondContact O-CG 3.47Å; F75-L79 PolarHBondContact O-N 3.14Å; M76-L79 PolarHBondContact O-N 2.95Å; L79-A81 VanDerWaalsContact C-N 3.27Å; L79-A81 PolarHBondContact O-N 3.27Å; L79-F82 HydrophobicContact CB-CB 3.73Å; L79-F82 PolarHBondContact O-N 3.02Å; L79-F82 VanDerWaalsContact O-N 3.14Å; L79-K83 PolarHBondContact O-N 3.37Å; L79-I175 HydrophobicContact CD1-CD1 3.55Å; L79-F176 HydrophobicContact CD1-CE2 4.36Å; L79-F176 HydrophobicContact CD1-CZ 4.1Å
80	P	96	Very high	96.4	Very high	93 Å²	93	53 Å²	53	60%	0.604	28%	0.284	S	S	*	.	H	α-helix	trans	-59.3	-37	179.9	-25.5	35.3	0	0	0	113.2	N78 Q84	N78-P80 VanDerWaalsContact O-CD 3.29Å; N78-P80 WeakPolarHBondContact O-CD 3.46Å; P80-Q84 WeakPolarHBondContact O-CG 3.38Å; P80-Q84 PolarHBondContact O-NE2 3.48Å; P80-Q84 VanDerWaalsContact O-NE2 3.1Å
81	A	95.9	Very high	96.4	Very high	22 Å²	22	53.2 Å²	53.2	18%	0.182	28%	0.276	C	S	.	.	H	α-helix	trans	-67.7	-37.8	177.5	0	0	0	0	0	112.2	L79 K83 Q84 F176 L192	L79-A81 VanDerWaalsContact C-N 3.27Å; L79-A81 PolarHBondContact O-N 3.27Å; A81-K83 PolarHBondContact O-N 3.2Å; A81-Q84 PolarHBondContact O-N 2.99Å; A81-F176 HydrophobicContact CB-CZ 4.21Å; A81-L192 HydrophobicContact CB-CD1 3.77Å; A81-L192 HydrophobicContact CB-CD2 3.57Å; A81-L192 HydrophobicContact CB-CG 4.34Å
82	F	96.8	Very high	96.4	Very high	1 Å²	1	49.6 Å²	49.6	0%	0.004	27%	0.265	C	S	.	.	H	α-helix	trans	-65.2	-39.8	177.6	-170.6	-91.7	0	0	0	111.8	M76 L79 Q84 L85 Q90 L93 I175 F176 L255	M76-F82 HydrophobicContact CE-CE2 3.72Å; M76-F82 HydrophobicContact CE-CZ 3.77Å; L79-F82 HydrophobicContact CB-CB 3.73Å; L79-F82 PolarHBondContact O-N 3.02Å; L79-F82 VanDerWaalsContact O-N 3.14Å; F82-Q84 PolarHBondContact O-N 3.32Å; F82-L85 HydrophobicContact CD2-CD1 4.07Å; F82-L85 WeakPolarHBondContact O-CB 3.38Å; F82-L85 PolarHBondContact O-N 2.88Å; F82-L85 VanDerWaalsContact O-N 3.16Å; F82-Q90 HydrophobicContact CD1-CG 4.15Å; F82-Q90 HydrophobicContact CE1-CB 3.79Å; F82-Q90 HydrophobicContact CE1-CG 3.69Å; F82-Q90 HydrophobicContact CZ-CB 3.72Å; F82-Q90 HydrophobicContact CZ-CG 3.93Å; F82-L93 HydrophobicContact CE2-CB 4.18Å; F82-L93 HydrophobicContact CE2-CD1 4.25Å; F82-I175 HydrophobicContact CD2-CG2 3.75Å; F82-I175 HydrophobicContact CE2-CG2 4.04Å; F82-F176 HydrophobicContact CB-CE1 4.35Å; F82-F176 HydrophobicContact CB-CZ 4.47Å; F82-F176 HydrophobicContact CD2-CE1 4.25Å; F82-L255 HydrophobicContact CE1-CD1 4.08Å; F82-L255 HydrophobicContact CE1-CD2 4.02Å; F82-L255 HydrophobicContact CZ-CD2 4.21Å
83	K	95.4	Very high	96.4	Very high	123 Å²	123	49.3 Å²	49.3	54%	0.535	26%	0.263	S	S	.	.	H	α-helix	trans	-63.1	-22.2	177	-67.2	178.1	-174.6	176.2	0	114.1	R77 L79 A81 L85	R77-K83 WeakPolarHBondContact O-CE 3.36Å; L79-K83 PolarHBondContact O-N 3.37Å; A81-K83 PolarHBondContact O-N 3.2Å; K83-L85 VanDerWaalsContact C-N 3.34Å
84	Q	95.9	Very high	96.5	Very high	139 Å²	139	49.1 Å²	49.1	65%	0.65	26%	0.262	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.9	-13.6	180	-69.7	170.7	58.5	0	0	112.7	P80 A81 F82 F188	P80-Q84 WeakPolarHBondContact O-CG 3.38Å; P80-Q84 PolarHBondContact O-NE2 3.48Å; P80-Q84 VanDerWaalsContact O-NE2 3.1Å; A81-Q84 PolarHBondContact O-N 2.99Å; F82-Q84 PolarHBondContact O-N 3.32Å; Q84-F188 HydrophobicContact CB-CE1 4.47Å
85	L	97.4	Very high	96.5	Very high	6 Å²	6	51.7 Å²	51.7	3%	0.031	27%	0.268	C	S	.	.	S	Bend	trans	-72.4	149.9	179.8	-65.8	169.5	0	0	0	111.4	F82 K83 D89 Q90 L93 F176 A185 F188 V189	F82-L85 HydrophobicContact CD2-CD1 4.07Å; F82-L85 WeakPolarHBondContact O-CB 3.38Å; F82-L85 PolarHBondContact O-N 2.88Å; F82-L85 VanDerWaalsContact O-N 3.16Å; K83-L85 VanDerWaalsContact C-N 3.34Å; L85-D89 HydrophobicContact CB-CB 4.37Å; L85-Q90 HydrophobicContact CB-CG 3.81Å; L85-Q90 PolarHBondContact O-NE2 3.16Å; L85-L93 HydrophobicContact CD1-CD1 3.51Å; L85-F176 HydrophobicContact CD1-CE1 4.41Å; L85-A185 HydrophobicContact CD2-CB 4Å; L85-F188 HydrophobicContact CD2-CD1 3.57Å; L85-F188 HydrophobicContact CD2-CE1 3.95Å; L85-F188 HydrophobicContact CG-CE1 4.48Å; L85-V189 HydrophobicContact CD1-CG2 4.42Å; L85-V189 HydrophobicContact CD2-CG2 3.79Å
86	P	97.3	Very high	96.6	Very high	35 Å²	35	51.5 Å²	51.5	23%	0.227	27%	0.274	C	S	.	.			trans	-52.5	143.2	168.8	-26.2	35.6	0	0	0	111.5	G88 D89 Q90 Q184 A185	P86-G88 PolarHBondContact O-N 3.45Å; P86-G88 VanDerWaalsContact O-N 3.17Å; P86-D89 HydrophobicContact CB-CB 4.36Å; P86-D89 WeakPolarHBondContact O-CB 3.41Å; P86-D89 PolarHBondContact O-N 3.09Å; P86-Q90 PolarHBondContact O-N 3.17Å; P86-Q184 HydrophobicContact CG-CB 4.21Å; P86-A185 HydrophobicContact CG-CB 4.45Å
87	P	95.7	Very high	96.6	Very high	94 Å²	94	51.6 Å²	51.6	61%	0.61	27%	0.274	S	S	*	.	H	α-helix	trans	-56.5	-33.9	179.7	-27.5	35	0	0	0	113.9	Q90 Y91	P87-Q90 PolarHBondContact O-N 2.98Å; P87-Y91 WeakPolarHBondContact O-CB 3.32Å; P87-Y91 PolarHBondContact O-N 3.42Å
88	G	97.3	Very high	96.8	Very high	41 Å²	41	48.8 Å²	48.8	42%	0.423	26%	0.264	S	S	.	.	H	α-helix	trans	-61.7	-45.1	173.9	0	0	0	0	0	112.5	P86 Y91 A92	P86-G88 PolarHBondContact O-N 3.45Å; P86-G88 VanDerWaalsContact O-N 3.17Å; G88-Y91 PolarHBondContact O-N 2.77Å; G88-A92 WeakPolarHBondContact O-CB 3.42Å; G88-A92 PolarHBondContact O-N 2.99Å
89	D	98.2	Very high	97	Very high	3 Å²	3	45.5 Å²	45.5	2%	0.016	25%	0.246	C	C	.	.	H	α-helix	trans	-66.7	-41.1	176.4	-68.5	9.3	0	0	0	111.2	L85 P86 Y91 A92 L93 L183 Q184 A185	L85-D89 HydrophobicContact CB-CB 4.37Å; P86-D89 HydrophobicContact CB-CB 4.36Å; P86-D89 WeakPolarHBondContact O-CB 3.41Å; P86-D89 PolarHBondContact O-N 3.09Å; D89-Y91 VanDerWaalsContact C-N 3.31Å; D89-Y91 PolarHBondContact O-N 3.38Å; D89-A92 PolarHBondContact O-N 3.26Å; D89-L93 WeakPolarHBondContact O-CB 3.35Å; D89-L93 VanDerWaalsContact O-CG 3.23Å; D89-L93 WeakPolarHBondContact O-CG 3.29Å; D89-L93 PolarHBondContact O-N 3.26Å; D89-L183 HydrophobicContact CB-CD2 3.83Å; D89-Q184 PolarHBondContact OD1-N 3.16Å; D89-Q184 PolarHBondContact OD2-N 2.95Å; D89-Q184 VanDerWaalsContact OD2-N 3.16Å; D89-A185 WeakPolarHBondContact OD2-CB 3.47Å; D89-A185 PolarHBondContact OD2-N 3Å
90	Q	97.7	Very high	97.1	Very high	24 Å²	24	44.9 Å²	44.9	11%	0.112	24%	0.244	C	C	.	.	H	α-helix	trans	-58.4	-43.5	174.6	-68.2	-176.3	45	0	0	111.5	F82 L85 P86 P87 L94 F256	F82-Q90 HydrophobicContact CD1-CG 4.15Å; F82-Q90 HydrophobicContact CE1-CB 3.79Å; F82-Q90 HydrophobicContact CE1-CG 3.69Å; F82-Q90 HydrophobicContact CZ-CB 3.72Å; F82-Q90 HydrophobicContact CZ-CG 3.93Å; L85-Q90 HydrophobicContact CB-CG 3.81Å; L85-Q90 PolarHBondContact O-NE2 3.16Å; P86-Q90 PolarHBondContact O-N 3.17Å; P87-Q90 PolarHBondContact O-N 2.98Å; Q90-L94 VanDerWaalsContact O-CB 3.3Å; Q90-L94 WeakPolarHBondContact O-CB 3.46Å; Q90-L94 PolarHBondContact O-N 2.99Å; Q90-F256 HydrophobicContact CB-CE1 4.25Å; Q90-F256 HydrophobicContact CB-CZ 4Å
91	Y	96.9	Very high	97.2	Very high	90 Å²	90	40.6 Å²	40.6	35%	0.353	22%	0.216	S	C	.	.	H	α-helix	trans	-64.4	-46.3	175.3	170.9	-100.4	0	0	0	112.1	P87 G88 D89 L93 L94 R95 V252	P87-Y91 WeakPolarHBondContact O-CB 3.32Å; P87-Y91 PolarHBondContact O-N 3.42Å; G88-Y91 PolarHBondContact O-N 2.77Å; D89-Y91 VanDerWaalsContact C-N 3.31Å; D89-Y91 PolarHBondContact O-N 3.38Å; Y91-L93 PolarHBondContact O-N 2.92Å; Y91-L94 PolarHBondContact O-N 3.13Å; Y91-R95 WeakPolarHBondContact O-CB 3.23Å; Y91-R95 PolarHBondContact O-N 2.77Å; Y91-V252 HydrophobicContact CD2-CG2 3.58Å; Y91-V252 HydrophobicContact CE2-CG2 3.59Å
92	A	97.9	Very high	97.4	Very high	24 Å²	24	39.5 Å²	39.5	20%	0.198	21%	0.208	C	C	.	.	H	α-helix	trans	-61.2	-44.6	179.5	0	0	0	0	0	111.6	G88 D89 R95 S96 V180 L183	G88-A92 WeakPolarHBondContact O-CB 3.42Å; G88-A92 PolarHBondContact O-N 2.99Å; D89-A92 PolarHBondContact O-N 3.26Å; A92-R95 PolarHBondContact O-N 3.01Å; A92-S96 WeakPolarHBondContact O-CB 3.41Å; A92-S96 PolarHBondContact O-N 3.12Å; A92-V180 HydrophobicContact CB-CG1 3.84Å; A92-L183 HydrophobicContact CB-CD2 4.25Å
93	L	98	Very high	97.5	Very high	1 Å²	1	39.5 Å²	39.5	1%	0.005	21%	0.208	C	C	.	.	H	α-helix	trans	-65.3	-46.3	175.7	-66.3	167.3	0	0	0	111.1	F82 L85 D89 Y91 R95 S96 C97 I175 V180 L183 V189	F82-L93 HydrophobicContact CE2-CB 4.18Å; F82-L93 HydrophobicContact CE2-CD1 4.25Å; L85-L93 HydrophobicContact CD1-CD1 3.51Å; D89-L93 WeakPolarHBondContact O-CB 3.35Å; D89-L93 VanDerWaalsContact O-CG 3.23Å; D89-L93 WeakPolarHBondContact O-CG 3.29Å; D89-L93 PolarHBondContact O-N 3.26Å; Y91-L93 PolarHBondContact O-N 2.92Å; L93-R95 VanDerWaalsContact C-N 3.32Å; L93-R95 PolarHBondContact O-N 3.22Å; L93-S96 PolarHBondContact O-N 3.07Å; L93-S96 VanDerWaalsContact O-N 3.07Å; L93-C97 PolarHBondContact O-N 3.11Å; L93-C97 PolarHBondContact O-SG 3Å; L93-I175 WeakPolarHBondContact CD2-O 3.43Å; L93-V180 HydrophobicContact CD2-CB 4.46Å; L93-V180 HydrophobicContact CD2-CG2 4.08Å; L93-L183 HydrophobicContact CD2-CD1 4.31Å; L93-L183 HydrophobicContact CD2-CD2 4.28Å; L93-L183 HydrophobicContact CG-CD2 4.13Å; L93-V189 HydrophobicContact CD1-CG2 4.23Å; L93-V189 HydrophobicContact CD2-CG1 4.28Å
94	L	97.5	Very high	97.6	Very high	1 Å²	1	33.7 Å²	33.7	1%	0.005	18%	0.182	C	C	.	.	H	α-helix	trans	-53.3	-50.4	174.9	175.8	70.4	0	0	0	111.2	M76 Q90 Y91 S96 C97 W98 L251 V252 L255	M76-L94 HydrophobicContact CE-CB 4.36Å; M76-L94 HydrophobicContact CE-CD1 4.11Å; M76-L94 HydrophobicContact SD-CD1 3.95Å; Q90-L94 VanDerWaalsContact O-CB 3.3Å; Q90-L94 WeakPolarHBondContact O-CB 3.46Å; Q90-L94 PolarHBondContact O-N 2.99Å; Y91-L94 PolarHBondContact O-N 3.13Å; L94-S96 PolarHBondContact O-N 2.75Å; L94-C97 PolarHBondContact O-N 3.17Å; L94-W98 HydrophobicContact CD1-CB 4.26Å; L94-W98 WeakPolarHBondContact O-CB 3.48Å; L94-W98 VanDerWaalsContact O-CD1 3.3Å; L94-W98 PolarHBondContact O-N 3.41Å; L94-L251 HydrophobicContact CD2-CB 4.12Å; L94-V252 HydrophobicContact CD2-CG2 3.93Å; L94-L255 HydrophobicContact CB-CD2 4.2Å; L94-L255 HydrophobicContact CD1-CD2 4.43Å; L94-L255 HydrophobicContact CD2-CB 4.38Å; L94-L255 HydrophobicContact CD2-CD2 3.83Å; L94-L255 HydrophobicContact CG-CD2 4.37Å
95	R	96.9	Very high	97.7	Very high	148 Å²	148	27.2 Å²	27.2	56%	0.558	15%	0.153	S	C	*	.	H	α-helix	trans	-58.2	-37.8	178.7	-178.1	-178.7	172.9	108.2	-1.3	112	Y91 A92 L93 L248	Y91-R95 WeakPolarHBondContact O-CB 3.23Å; Y91-R95 PolarHBondContact O-N 2.77Å; A92-R95 PolarHBondContact O-N 3.01Å; L93-R95 VanDerWaalsContact C-N 3.32Å; L93-R95 PolarHBondContact O-N 3.22Å; R95-L248 HydrophobicContact CB-CD1 4.28Å; R95-L248 HydrophobicContact CB-CD2 4.44Å; R95-L248 HydrophobicContact CG-CD1 4.49Å; R95-L248 HydrophobicContact CG-CD2 3.95Å
96	S	96.9	Very high	97.8	Very high	52 Å²	52	26.9 Å²	26.9	36%	0.364	15%	0.151	S	C	.	.	H	α-helix	trans	-74.7	-42.5	179.9	-175.7	0	0	0	0	113.2	A92 L93 L94 V180	A92-S96 WeakPolarHBondContact O-CB 3.41Å; A92-S96 PolarHBondContact O-N 3.12Å; L93-S96 PolarHBondContact O-N 3.07Å; L93-S96 VanDerWaalsContact O-N 3.07Å; L94-S96 PolarHBondContact O-N 2.75Å; S96-V180 WeakPolarHBondContact OG-CG2 3.07Å
97	C	97.3	Very high	97.9	Very high	2 Å²	2	25.2 Å²	25.2	1%	0.014	14%	0.14	C	C	.	.	H	α-helix	trans	-107.3	-10.7	-165.5	71.4	0	0	0	0	115.6	M76 L93 L94 A99 P100 L101 T174	M76-C97 WeakPolarHBondContact CE-SG 3.25Å; L93-C97 PolarHBondContact O-N 3.11Å; L93-C97 PolarHBondContact O-SG 3Å; L94-C97 PolarHBondContact O-N 3.17Å; C97-A99 VanDerWaalsContact C-N 3.27Å; C97-A99 PolarHBondContact O-N 3.49Å; C97-P100 WeakPolarHBondContact O-CD 3.47Å; C97-L101 HydrophobicContact CB-CD1 4.05Å; C97-L101 HydrophobicContact CB-CG 4.28Å; C97-L101 WeakPolarHBondContact O-CB 3.35Å; C97-L101 WeakPolarHBondContact O-CG 3.39Å; C97-L101 PolarHBondContact O-N 3.33Å; C97-L101 WeakPolarHBondContact SG-CD1 3.32Å; C97-T174 HydrophobicContact CB-CG2 4.32Å; C97-T174 WeakPolarHBondContact CB-O 3.35Å
98	W	97.9	Very high	98	Very high	17 Å²	17	23.5 Å²	23.5	6%	0.064	12%	0.124	C	C	.	.	H	α-helix	trans	-56.6	-40.7	-175	75.2	-95	0	0	0	113	L69 L94 F102 P230 I233 L247 L251	L69-W98 HydrophobicContact CD1-CE3 4.48Å; L94-W98 HydrophobicContact CD1-CB 4.26Å; L94-W98 WeakPolarHBondContact O-CB 3.48Å; L94-W98 VanDerWaalsContact O-CD1 3.3Å; L94-W98 PolarHBondContact O-N 3.41Å; W98-F102 WeakPolarHBondContact O-CB 3.38Å; W98-F102 PolarHBondContact O-N 3.38Å; W98-P230 HydrophobicContact CH2-CB 4.03Å; W98-P230 WeakPolarHBondContact CH2-O 3.28Å; W98-P230 HydrophobicContact CZ2-CB 3.36Å; W98-I233 HydrophobicContact CH2-CB 4.27Å; W98-I233 HydrophobicContact CH2-CG2 4.13Å; W98-I233 HydrophobicContact CZ3-CB 4.38Å; W98-I233 HydrophobicContact CZ3-CG2 3.81Å; W98-L247 HydrophobicContact CH2-CD2 3.63Å; W98-L247 HydrophobicContact CZ2-CD2 4.31Å; W98-L247 HydrophobicContact CZ3-CD2 3.78Å; W98-L251 HydrophobicContact CB-CD1 3.87Å; W98-L251 HydrophobicContact CD2-CD1 3.67Å; W98-L251 HydrophobicContact CE3-CD1 3.97Å; W98-L251 HydrophobicContact CG-CD1 3.64Å
99	A	98.3	Very high	98	Very high	1 Å²	1	26 Å²	26	1%	0.008	13%	0.125	C	C	.	.	H	α-helix	trans	-70.9	-52.8	-178.6	0	0	0	0	0	112.1	C97 L101 F102 I103 P230 I233	C97-A99 VanDerWaalsContact C-N 3.27Å; C97-A99 PolarHBondContact O-N 3.49Å; A99-L101 VanDerWaalsContact C-N 3.3Å; A99-L101 PolarHBondContact O-N 2.92Å; A99-F102 WeakPolarHBondContact O-CB 3.49Å; A99-F102 PolarHBondContact O-N 3.04Å; A99-I103 WeakPolarHBondContact O-CG1 3.49Å; A99-I103 PolarHBondContact O-N 3.14Å; A99-P230 HydrophobicContact CB-CB 3.87Å; A99-P230 HydrophobicContact CB-CG 3.93Å; A99-I233 HydrophobicContact CB-CD1 3.64Å
100	P	98.4	Very high	98	Very high	26 Å²	26	31.4 Å²	31.4	17%	0.169	15%	0.15	C	C	.	.	H	α-helix	trans	-52.1	-44.6	170.4	-30.6	35.8	0	0	0	113.7	C97 I103 L104 T174 L225	C97-P100 WeakPolarHBondContact O-CD 3.47Å; P100-I103 PolarHBondContact O-N 3.39Å; P100-L104 WeakPolarHBondContact O-CG 3.3Å; P100-L104 PolarHBondContact O-N 3.23Å; P100-T174 HydrophobicContact CB-CG2 3.62Å; P100-L225 HydrophobicContact CB-CB 4.19Å; P100-L225 HydrophobicContact CB-CD1 4.16Å
101	L	98.6	Very high	98	Very high	2 Å²	2	30.5 Å²	30.5	1%	0.01	15%	0.146	C	C	.	.	H	α-helix	trans	-67.5	-36.8	178.9	-68.4	172.7	0	0	0	112.8	T72 M76 C97 A99 L104 G105 K171 T174 I175	T72-L101 HydrophobicContact CG2-CB 3.52Å; T72-L101 HydrophobicContact CG2-CD1 4.21Å; M76-L101 HydrophobicContact CE-CD1 4.37Å; M76-L101 HydrophobicContact CG-CD1 3.86Å; M76-L101 HydrophobicContact SD-CD1 3.48Å; M76-L101 WeakPolarHBondContact SD-CD1 3.4Å; C97-L101 HydrophobicContact CB-CD1 4.05Å; C97-L101 HydrophobicContact CB-CG 4.28Å; C97-L101 WeakPolarHBondContact O-CB 3.35Å; C97-L101 WeakPolarHBondContact O-CG 3.39Å; C97-L101 PolarHBondContact O-N 3.33Å; C97-L101 WeakPolarHBondContact SG-CD1 3.32Å; A99-L101 VanDerWaalsContact C-N 3.3Å; A99-L101 PolarHBondContact O-N 2.92Å; L101-L104 HydrophobicContact CD2-CD1 4.48Å; L101-L104 PolarHBondContact O-N 2.93Å; L101-G105 PolarHBondContact O-N 3.49Å; L101-K171 HydrophobicContact CD2-CB 3.72Å; L101-K171 HydrophobicContact CD2-CG 3.75Å; L101-T174 HydrophobicContact CD2-CG2 4Å; L101-T174 HydrophobicContact CG-CG2 4.18Å; L101-I175 HydrophobicContact CD1-CD1 4.14Å; L101-I175 HydrophobicContact CD1-CG1 3.52Å; L101-I175 HydrophobicContact CD2-CD1 4.37Å; L101-I175 HydrophobicContact CD2-CG1 3.97Å; L101-I175 HydrophobicContact CG-CG1 4.3Å
102	F	98.7	Very high	97.9	Very high	0 Å²	0	30.5 Å²	30.5	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-62.1	-44.8	173.7	174.1	-101.8	0	0	0	111.3	A65 V68 L69 W98 A99 L104 G105 L106 I233 F237 F238	A65-F102 HydrophobicContact CB-CE2 4.13Å; A65-F102 HydrophobicContact CB-CZ 3.78Å; A65-F102 WeakPolarHBondContact O-CE2 3.32Å; V68-F102 HydrophobicContact CB-CD2 4.4Å; V68-F102 HydrophobicContact CB-CE2 4.05Å; V68-F102 HydrophobicContact CG1-CD2 3.8Å; V68-F102 HydrophobicContact CG1-CE2 3.86Å; L69-F102 HydrophobicContact CB-CD2 4.27Å; L69-F102 HydrophobicContact CB-CE2 4.44Å; L69-F102 HydrophobicContact CD1-CB 4.48Å; L69-F102 HydrophobicContact CD1-CD2 3.91Å; L69-F102 HydrophobicContact CD1-CG 4.41Å; W98-F102 WeakPolarHBondContact O-CB 3.38Å; W98-F102 PolarHBondContact O-N 3.38Å; A99-F102 WeakPolarHBondContact O-CB 3.49Å; A99-F102 PolarHBondContact O-N 3.04Å; F102-L104 PolarHBondContact O-N 3.43Å; F102-G105 CarbonylContact O-C 3.51Å; F102-G105 WeakPolarHBondContact O-CA 3.29Å; F102-G105 PolarHBondContact O-N 3.44Å; F102-G105 VanDerWaalsContact O-N 3.09Å; F102-L106 HydrophobicContact CD1-CD1 4.08Å; F102-L106 HydrophobicContact CD1-CG 4.33Å; F102-L106 HydrophobicContact CE1-CD1 3.41Å; F102-L106 VanDerWaalsContact CE1-CD1 3.41Å; F102-L106 HydrophobicContact CE1-CD2 4.25Å; F102-L106 HydrophobicContact CE1-CG 3.81Å; F102-L106 HydrophobicContact CE2-CD2 4.1Å; F102-L106 HydrophobicContact CE2-CG 4.19Å; F102-L106 HydrophobicContact CZ-CD1 3.74Å; F102-L106 HydrophobicContact CZ-CD2 3.69Å; F102-L106 HydrophobicContact CZ-CG 3.74Å; F102-L106 PolarHBondContact O-N 2.86Å; F102-I233 HydrophobicContact CD1-CD1 4.34Å; F102-I233 HydrophobicContact CD1-CG2 3.4Å; F102-I233 HydrophobicContact CE1-CG2 3.48Å; F102-I233 VanDerWaalsContact CE1-CG2 3.48Å; F102-I233 HydrophobicContact CG-CG2 4.35Å; F102-F237 AromaticContact CE1-CD2 3.86Å; F102-F237 HydrophobicContact CE1-CD2 3.86Å; F102-F237 HydrophobicContact CE1-CE2 4.16Å; F102-F237 HydrophobicContact CE1-CG 4.3Å; F102-F237 HydrophobicContact CZ-CB 4.44Å; F102-F237 HydrophobicContact CZ-CD2 4.26Å; F102-F237 HydrophobicContact CZ-CG 4.23Å; F102-F238 HydrophobicContact CD1-CE2 4.49Å; F102-F238 HydrophobicContact CD2-CE2 4.38Å; F102-F238 AromaticContact CD2-CZ 3.96Å; F102-F238 HydrophobicContact CD2-CZ 3.96Å; F102-F238 HydrophobicContact CE1-CE2 4.1Å; F102-F238 HydrophobicContact CE1-CZ 4.32Å; F102-F238 HydrophobicContact CE2-CE2 4.05Å; F102-F238 AromaticContact CE2-CZ 3.46Å; F102-F238 HydrophobicContact CE2-CZ 3.46Å; F102-F238 VanDerWaalsContact CE2-CZ 3.46Å; F102-F238 AromaticContact CZ-CE2 3.87Å; F102-F238 HydrophobicContact CZ-CE2 3.87Å; F102-F238 AromaticContact CZ-CZ 3.64Å; F102-F238 HydrophobicContact CZ-CZ 3.64Å
103	I	98.7	Very high	97.9	Very high	1 Å²	1	29.3 Å²	29.3	1%	0.005	14%	0.142	C	C	.	.	H	α-helix	trans	-62.1	-44	175.8	-60.2	160.5	0	0	0	110.9	A99 P100 G105 L106 A107 L150 L154 L225 I228 I233	A99-I103 WeakPolarHBondContact O-CG1 3.49Å; A99-I103 PolarHBondContact O-N 3.14Å; P100-I103 PolarHBondContact O-N 3.39Å; I103-G105 PolarHBondContact O-N 3.01Å; I103-L106 PolarHBondContact O-N 3.43Å; I103-A107 PolarHBondContact O-N 3.09Å; I103-L150 HydrophobicContact CD1-CD1 4.42Å; I103-L150 HydrophobicContact CG1-CD1 4Å; I103-L150 HydrophobicContact CG2-CD1 4.07Å; I103-L154 HydrophobicContact CG2-CD2 3.95Å; I103-L225 HydrophobicContact CB-CD2 3.72Å; I103-L225 HydrophobicContact CD1-CD2 3.95Å; I103-L225 HydrophobicContact CG1-CD2 4.49Å; I103-L225 HydrophobicContact CG2-CD2 3.53Å; I103-I228 HydrophobicContact CD1-CB 3.92Å; I103-I228 HydrophobicContact CD1-CD1 3.77Å; I103-I228 HydrophobicContact CD1-CG1 4.46Å; I103-I228 HydrophobicContact CD1-CG2 3.81Å; I103-I233 HydrophobicContact CD1-CD1 3.87Å; I103-I233 HydrophobicContact CG1-CD1 3.83Å
104	L	98.8	Very high	97.8	Very high	0 Å²	0	33 Å²	33	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-60.1	-36.6	173.7	-71.3	177.1	0	0	0	111.8	P100 L101 F102 A107 Q108 F157 L170 K171 L225	P100-L104 WeakPolarHBondContact O-CG 3.3Å; P100-L104 PolarHBondContact O-N 3.23Å; L101-L104 HydrophobicContact CD2-CD1 4.48Å; L101-L104 PolarHBondContact O-N 2.93Å; F102-L104 PolarHBondContact O-N 3.43Å; L104-A107 PolarHBondContact O-N 2.87Å; L104-Q108 VanDerWaalsContact O-CB 3.3Å; L104-Q108 WeakPolarHBondContact O-CB 3.45Å; L104-Q108 PolarHBondContact O-N 3.02Å; L104-F157 HydrophobicContact CD2-CD1 4.14Å; L104-F157 HydrophobicContact CD2-CE1 3.5Å; L104-F157 HydrophobicContact CD2-CE2 4.01Å; L104-F157 HydrophobicContact CD2-CZ 3.41Å; L104-F157 VanDerWaalsContact CD2-CZ 3.41Å; L104-L170 HydrophobicContact CD1-CD2 4.3Å; L104-L170 HydrophobicContact CD1-CG 4.11Å; L104-L170 HydrophobicContact CD2-CD2 3.69Å; L104-L170 HydrophobicContact CD2-CG 4.39Å; L104-K171 HydrophobicContact CB-CG 4.44Å; L104-K171 HydrophobicContact CD1-CG 4Å; L104-L225 HydrophobicContact CD1-CD1 4.2Å; L104-L225 HydrophobicContact CD2-CD1 4.08Å; L104-L225 HydrophobicContact CG-CD1 3.97Å
105	G	98.6	Very high	97.7	Very high	3 Å²	3	34 Å²	34	3%	0.031	17%	0.168	C	C	.	.	H	α-helix	trans	-65.3	-44.8	173.9	0	0	0	0	0	113	V68 L101 F102 I103 A107 Q108 E109	V68-G105 VanDerWaalsContact CG1-C 3.49Å; L101-G105 PolarHBondContact O-N 3.49Å; F102-G105 CarbonylContact O-C 3.51Å; F102-G105 WeakPolarHBondContact O-CA 3.29Å; F102-G105 PolarHBondContact O-N 3.44Å; F102-G105 VanDerWaalsContact O-N 3.09Å; I103-G105 PolarHBondContact O-N 3.01Å; G105-A107 VanDerWaalsContact C-N 3.3Å; G105-A107 PolarHBondContact O-N 3.36Å; G105-Q108 PolarHBondContact O-N 3.27Å; G105-E109 WeakPolarHBondContact O-CB 3.4Å; G105-E109 WeakPolarHBondContact O-CG 3.4Å; G105-E109 PolarHBondContact O-N 3.44Å
106	L	98.7	Very high	97.5	Very high	0 Å²	0	30.5 Å²	30.5	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-59.5	-43.6	173.9	-70.2	179.6	0	0	0	111	V68 F102 I103 H110 V111 L154 F237	V68-L106 HydrophobicContact CB-CD2 4.49Å; V68-L106 HydrophobicContact CG1-CD2 4.43Å; V68-L106 HydrophobicContact CG2-CD2 4.28Å; F102-L106 HydrophobicContact CD1-CD1 4.08Å; F102-L106 HydrophobicContact CD1-CG 4.33Å; F102-L106 HydrophobicContact CE1-CD1 3.41Å; F102-L106 VanDerWaalsContact CE1-CD1 3.41Å; F102-L106 HydrophobicContact CE1-CD2 4.25Å; F102-L106 HydrophobicContact CE1-CG 3.81Å; F102-L106 HydrophobicContact CE2-CD2 4.1Å; F102-L106 HydrophobicContact CE2-CG 4.19Å; F102-L106 HydrophobicContact CZ-CD1 3.74Å; F102-L106 HydrophobicContact CZ-CD2 3.69Å; F102-L106 HydrophobicContact CZ-CG 3.74Å; F102-L106 PolarHBondContact O-N 2.86Å; I103-L106 PolarHBondContact O-N 3.43Å; L106-H110 PolarHBondContact O-N 3.06Å; L106-H110 VanDerWaalsContact O-N 3.11Å; L106-V111 HydrophobicContact CB-CB 4.41Å; L106-V111 HydrophobicContact CD2-CB 3.72Å; L106-V111 HydrophobicContact CD2-CG1 3.8Å; L106-V111 HydrophobicContact CD2-CG2 3.97Å; L106-V111 PolarHBondContact O-N 3.26Å; L106-L154 HydrophobicContact CB-CD2 3.91Å; L106-F237 HydrophobicContact CD1-CE2 4.19Å; L106-F237 HydrophobicContact CD1-CZ 3.99Å
107	A	98.6	Very high	97.2	Very high	0 Å²	0	31 Å²	31	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-62.2	-47.9	177.5	0	0	0	0	0	111.5	I103 L104 G105 E109 H110 L154 F157 W158 Y167	I103-A107 PolarHBondContact O-N 3.09Å; L104-A107 PolarHBondContact O-N 2.87Å; G105-A107 VanDerWaalsContact C-N 3.3Å; G105-A107 PolarHBondContact O-N 3.36Å; A107-E109 VanDerWaalsContact C-N 3.32Å; A107-E109 PolarHBondContact O-N 3.18Å; A107-H110 PolarHBondContact O-N 3.2Å; A107-H110 VanDerWaalsContact O-N 3.17Å; A107-L154 HydrophobicContact CB-CD2 3.93Å; A107-F157 HydrophobicContact CB-CB 3.69Å; A107-F157 HydrophobicContact CB-CG 4.18Å; A107-W158 PolarHBondContact O-NE1 3.01Å; A107-W158 VanDerWaalsContact O-NE1 3.09Å; A107-Y167 HydrophobicContact CB-CE1 4.34Å
108	Q	98.5	Very high	96.5	Very high	58 Å²	58	33.7 Å²	33.7	27%	0.271	18%	0.178	S	C	.	.	H	α-helix	trans	-62.6	-36.3	-179.5	-177.1	174.6	0	0	0	113	L104 G105 H110 Y167	L104-Q108 VanDerWaalsContact O-CB 3.3Å; L104-Q108 WeakPolarHBondContact O-CB 3.45Å; L104-Q108 PolarHBondContact O-N 3.02Å; G105-Q108 PolarHBondContact O-N 3.27Å; Q108-H110 VanDerWaalsContact C-N 3.31Å; Q108-Y167 HydrophobicContact CB-CD1 4.04Å; Q108-Y167 HydrophobicContact CB-CD2 3.98Å; Q108-Y167 HydrophobicContact CB-CE1 3.92Å; Q108-Y167 HydrophobicContact CB-CE2 3.82Å; Q108-Y167 HydrophobicContact CB-CG 4.08Å; Q108-Y167 HydrophobicContact CG-CD1 4.49Å; Q108-Y167 HydrophobicContact CG-CD2 3.73Å; Q108-Y167 HydrophobicContact CG-CE2 3.92Å; Q108-Y167 HydrophobicContact CG-CG 4.02Å; Q108-Y167 PolarHBondContact N-OH 3.2Å
109	E	97.9	Very high	95.2	Very high	92 Å²	92	38.2 Å²	38.2	43%	0.43	21%	0.21	S	C	.	.	T	Hydrogen-bonded Turn	trans	-91.2	4.7	180	-60.6	-79.3	161.1	0	0	112.5	V68 K71 G105 A107 V111	V68-E109 HydrophobicContact CG2-CB 4.25Å; V68-E109 HydrophobicContact CG2-CG 4.07Å; K71-E109 IonicContact NZ-OE1 3.6Å; K71-E109 PolarHBondContact NZ-OE1 3.26Å; K71-E109 IonicContact NZ-OE2 3.43Å; K71-E109 PolarHBondContact NZ-OE2 3.16Å; G105-E109 WeakPolarHBondContact O-CB 3.4Å; G105-E109 WeakPolarHBondContact O-CG 3.4Å; G105-E109 PolarHBondContact O-N 3.44Å; A107-E109 VanDerWaalsContact C-N 3.32Å; A107-E109 PolarHBondContact O-N 3.18Å; E109-V111 HydrophobicContact CB-CG2 4.06Å; E109-V111 PolarHBondContact O-N 2.88Å
110	H	97.6	Very high	93.7	Very high	118 Å²	118	42.8 Å²	42.8	55%	0.546	25%	0.247	S	C	.	.	T	Hydrogen-bonded Turn	trans	52.5	38.9	-178.7	-70.6	-91.2	0	0	0	114	L106 A107 Q108 D112 W158	L106-H110 PolarHBondContact O-N 3.06Å; L106-H110 VanDerWaalsContact O-N 3.11Å; A107-H110 PolarHBondContact O-N 3.2Å; A107-H110 VanDerWaalsContact O-N 3.17Å; Q108-H110 VanDerWaalsContact C-N 3.31Å; H110-D112 PolarHBondContact O-N 2.87Å; H110-D112 VanDerWaalsContact O-N 3.17Å; H110-W158 AromaticContact CE1-CD1 3.58Å; H110-W158 AromaticContact ND1-CD1 3.4Å; H110-W158 AromaticContact ND1-CG 3.95Å; H110-W158 AromaticContact ND1-NE1 3.59Å
111	V	97.4	Very high	92	Very high	5 Å²	5	43.7 Å²	43.7	3%	0.03	25%	0.25	C	S	.	.			trans	-72.1	110.9	177.3	179.2	0	0	0	0	109.4	E64 V68 L106 E109	E64-V111 HydrophobicContact CB-CG1 4.38Å; E64-V111 HydrophobicContact CB-CG2 4.3Å; V68-V111 HydrophobicContact CG2-CG2 4.2Å; L106-V111 HydrophobicContact CB-CB 4.41Å; L106-V111 HydrophobicContact CD2-CB 3.72Å; L106-V111 HydrophobicContact CD2-CG1 3.8Å; L106-V111 HydrophobicContact CD2-CG2 3.97Å; L106-V111 PolarHBondContact O-N 3.26Å; E109-V111 HydrophobicContact CB-CG2 4.06Å; E109-V111 PolarHBondContact O-N 2.88Å
112	D	95.4	Very high	90.3	Very high	89 Å²	89	46.7 Å²	46.7	48%	0.476	27%	0.272	S	S	.	.			trans	-106.4	147.1	172.9	-166.3	21.3	0	0	0	110.8	H110 W158	H110-D112 PolarHBondContact O-N 2.87Å; H110-D112 VanDerWaalsContact O-N 3.17Å; D112-W158 HydrophobicContact CB-CH2 4.12Å
113	F	97.5	Very high	88.7	Confident	0 Å²	0	54 Å²	54	0%	0	31%	0.308	C	S	.	.			trans	-151	149.2	-173.7	63.5	-88.2	0	0	0	111.7	L55 V61 V115 V147 L150 R151 L154 L236 F237	L55-F113 HydrophobicContact CD2-CB 4.12Å; L55-F113 HydrophobicContact CD2-CD2 3.68Å; L55-F113 HydrophobicContact CD2-CG 4.17Å; V61-F113 HydrophobicContact CB-CB 4.43Å; V61-F113 HydrophobicContact CG1-CB 3.68Å; V61-F113 HydrophobicContact CG1-CG 4.39Å; V61-F113 HydrophobicContact CG2-CB 3.83Å; F113-V115 HydrophobicContact CD2-CG1 4.17Å; F113-V115 HydrophobicContact CE2-CG1 4.23Å; F113-V147 HydrophobicContact CE2-CG1 3.91Å; F113-L150 HydrophobicContact CE1-CD2 4.34Å; F113-L150 HydrophobicContact CZ-CD2 3.75Å; F113-L150 HydrophobicContact CZ-CG 4.16Å; F113-R151 HydrophobicContact CE2-CG 4.31Å; F113-R151 HydrophobicContact CZ-CG 3.97Å; F113-R151 PolarHBondContact O-NE 2.69Å; F113-R151 PolarHBondContact O-NH2 2.88Å; F113-L154 HydrophobicContact CE1-CD1 3.74Å; F113-L236 HydrophobicContact CE2-CD2 3.93Å; F113-L236 HydrophobicContact CZ-CD2 4.36Å; F113-F237 HydrophobicContact CD1-CE1 4.01Å; F113-F237 AromaticContact CD1-CZ 3.96Å; F113-F237 HydrophobicContact CD1-CZ 3.96Å; F113-F237 HydrophobicContact CD2-CZ 4.49Å; F113-F237 HydrophobicContact CE1-CE1 4.16Å; F113-F237 AromaticContact CE1-CZ 3.62Å; F113-F237 HydrophobicContact CE1-CZ 3.62Å; F113-F237 HydrophobicContact CE2-CZ 4.19Å; F113-F237 HydrophobicContact CG-CE1 4.21Å; F113-F237 HydrophobicContact CG-CZ 4.39Å; F113-F237 HydrophobicContact CZ-CE1 4.49Å; F113-F237 AromaticContact CZ-CZ 3.75Å; F113-F237 HydrophobicContact CZ-CZ 3.75Å
114	D	95.9	Very high	87.2	Confident	79 Å²	79	59.8 Å²	59.8	42%	0.422	34%	0.338	S	S	.	.			trans	-108.5	147.4	174.7	-75.8	-53.9	0	0	0	113.8	L55 V56 R151	L55-D114 CarbonylContact C-O 3.56Å; L55-D114 WeakPolarHBondContact CA-O 3.49Å; V56-D114 HydrophobicContact CB-CB 4.05Å; V56-D114 HydrophobicContact CG2-CB 3.79Å; V56-D114 PolarHBondContact N-O 3.03Å; D114-R151 VanDerWaalsContact CA-NH2 3.28Å; D114-R151 IonicContact OD1-CZ 3.55Å; D114-R151 IonicContact OD1-NH2 2.99Å; D114-R151 PolarHBondContact OD1-NH2 2.75Å
115	V	95.3	Very high	85.6	Confident	20 Å²	20	64.5 Å²	64.5	12%	0.121	36%	0.358	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.7	151.6	175.6	-61.4	0	0	0	0	111.4	V53 C54 L55 F113 M144 V147 L236	V53-V115 HydrophobicContact CB-CB 4.2Å; V53-V115 HydrophobicContact CB-CG2 4.44Å; V53-V115 HydrophobicContact CG2-CB 4.24Å; V53-V115 HydrophobicContact CG2-CG1 4.48Å; V53-V115 HydrophobicContact CG2-CG2 4.34Å; C54-V115 CarbonylContact O-C 3.55Å; C54-V115 WeakPolarHBondContact O-CA 3.36Å; C54-V115 WeakPolarHBondContact O-CB 3.5Å; L55-V115 HydrophobicContact CD2-CG1 4.25Å; F113-V115 HydrophobicContact CD2-CG1 4.17Å; F113-V115 HydrophobicContact CE2-CG1 4.23Å; V115-M144 HydrophobicContact CG2-CE 4.18Å; V115-M144 HydrophobicContact CG2-SD 3.68Å; V115-V147 HydrophobicContact CB-CG1 4.49Å; V115-V147 HydrophobicContact CG1-CG1 3.86Å; V115-V147 HydrophobicContact CG1-CG2 4.36Å; V115-V147 HydrophobicContact CG2-CG1 3.83Å; V115-L236 HydrophobicContact CG1-CD1 4.2Å
116	T	93.3	Very high	84.1	Confident	75 Å²	75	69.6 Å²	69.6	46%	0.46	38%	0.38	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.7	156.7	174.5	-167.1	0	0	0	0	110	V53 C54 V56 V118	V53-T116 VanDerWaalsContact CA-O 3.25Å; V53-T116 WeakPolarHBondContact CA-O 3.42Å; V53-T116 WeakPolarHBondContact CB-O 3.47Å; C54-T116 PolarHBondContact N-O 3.08Å; C54-T116 PolarHBondContact O-N 3.04Å; V56-T116 HydrophobicContact CG2-CG2 4.3Å; T116-V118 PolarHBondContact O-N 3.04Å
117	D	89.8	Confident	82.8	Confident	63 Å²	63	75.1 Å²	75.1	34%	0.337	41%	0.408	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-63	132.5	176.7	-76	-32	0	0	0	109.7	R51 P119	R51-D117 IonicContact NH1-OD2 2.74Å; D117-P119 WeakPolarHBondContact O-CD 3.46Å
118	V	82.3	Confident	81.4	Confident	59 Å²	59	81.9 Å²	81.9	36%	0.358	44%	0.444	S	S	.	.	P	Polyproline II helix	trans	-77.9	120.7	166.6	-178.5	0	0	0	0	107.1	T52 C54 T116 A120	T52-V118 WeakPolarHBondContact O-CB 3.41Å; T52-V118 PolarHBondContact O-N 3.39Å; C54-V118 HydrophobicContact CB-CG2 3.71Å; T116-V118 PolarHBondContact O-N 3.04Å; V118-A120 PolarHBondContact O-N 3.45Å; V118-A120 VanDerWaalsContact O-N 3.14Å
119	P	70.4	Confident	80.2	Confident	112 Å²	112	84.6 Å²	84.6	73%	0.727	46%	0.459	S	S	*	.	P	Polyproline II helix	trans	-59.1	123.4	174	-20.1	31.5	0	0	0	109	D117 D121	D117-P119 WeakPolarHBondContact O-CD 3.46Å; P119-D121 PolarHBondContact O-N 2.92Å
120	A	66.5	Low	78.1	Confident	96 Å²	96	86.4 Å²	86.4	79%	0.793	47%	0.472	S	S	*	.	P	Polyproline II helix	trans	-59.2	125.3	174.7	0	0	0	0	0	108.9	V118 S122	V118-A120 PolarHBondContact O-N 3.45Å; V118-A120 VanDerWaalsContact O-N 3.14Å; A120-S122 PolarHBondContact O-N 3.18Å; A120-S122 VanDerWaalsContact O-N 3.17Å
121	D	64	Low	76.1	Confident	45 Å²	45	86.3 Å²	86.3	24%	0.241	47%	0.467	C	S	.	.	P	Polyproline II helix	trans	-54.4	125.5	169.8	-86.6	-25.4	0	0	0	108.3	P119 K125 K126 R131	P119-D121 PolarHBondContact O-N 2.92Å; D121-K125 WeakPolarHBondContact OD1-CD 3.19Å; D121-K125 WeakPolarHBondContact OD1-CE 3.28Å; D121-K125 IonicContact OD1-NZ 2.77Å; D121-K125 PolarHBondContact OD1-NZ 2.86Å; D121-K126 HydrophobicContact CB-CG 4Å; D121-R131 IonicContact OD2-NH1 3.06Å; D121-R131 PolarHBondContact OD2-NH1 3.35Å
122	S	63.3	Low	73.8	Confident	66 Å²	66	93.8 Å²	93.8	46%	0.462	50%	0.502	S	S	.	.	P	Polyproline II helix	trans	-57.5	144.7	177.6	73	0	0	0	0	109.3	A120 L124 K125 K126	A120-S122 PolarHBondContact O-N 3.18Å; A120-S122 VanDerWaalsContact O-N 3.17Å; S122-L124 PolarHBondContact O-N 2.96Å; S122-L124 VanDerWaalsContact O-N 3.14Å; S122-K125 WeakPolarHBondContact O-CA 3.29Å; S122-K125 WeakPolarHBondContact O-CB 3.4Å; S122-K125 PolarHBondContact O-N 3.21Å; S122-K125 WeakPolarHBondContact OG-CB 3.31Å; S122-K125 PolarHBondContact OG-N 3.37Å; S122-K125 VanDerWaalsContact OG-N 3.07Å; S122-K126 PolarHBondContact O-N 2.96Å
123	M	63.8	Low	71.5	Confident	154 Å²	154	98 Å²	98	76%	0.759	52%	0.518	S	S	*	.	H	α-helix	trans	-53.8	-36.8	177.3	-71.5	-175.6	64.3	0	0	111.2	K126 I127	M123-K126 PolarHBondContact O-N 3.47Å; M123-I127 WeakPolarHBondContact O-CD1 3.49Å; M123-I127 VanDerWaalsContact O-CG1 3.23Å; M123-I127 WeakPolarHBondContact O-CG1 3.48Å; M123-I127 PolarHBondContact O-N 3.34Å
124	L	67.4	Low	69.1	Low	121 Å²	121	99.3 Å²	99.3	63%	0.634	53%	0.528	S	S	*	.	H	α-helix	trans	-60.1	-45.5	172.7	-70.3	173.4	0	0	0	112.4	S122 K126 I127 L128	S122-L124 PolarHBondContact O-N 2.96Å; S122-L124 VanDerWaalsContact O-N 3.14Å; L124-K126 VanDerWaalsContact C-N 3.31Å; L124-K126 PolarHBondContact O-N 2.92Å; L124-I127 PolarHBondContact O-N 3.32Å; L124-L128 VanDerWaalsContact O-CB 3.23Å; L124-L128 WeakPolarHBondContact O-CB 3.34Å; L124-L128 WeakPolarHBondContact O-CG 3.49Å; L124-L128 PolarHBondContact O-N 3.07Å
125	K	65.4	Low	66.9	Low	99 Å²	99	99.9 Å²	99.9	43%	0.43	54%	0.536	S	S	.	.	H	α-helix	trans	-63	-37.7	176.8	-173.5	177.4	172.3	-158.6	0	111.8	D121 S122 L129	D121-K125 WeakPolarHBondContact OD1-CD 3.19Å; D121-K125 WeakPolarHBondContact OD1-CE 3.28Å; D121-K125 IonicContact OD1-NZ 2.77Å; D121-K125 PolarHBondContact OD1-NZ 2.86Å; S122-K125 WeakPolarHBondContact O-CA 3.29Å; S122-K125 WeakPolarHBondContact O-CB 3.4Å; S122-K125 PolarHBondContact O-N 3.21Å; S122-K125 WeakPolarHBondContact OG-CB 3.31Å; S122-K125 PolarHBondContact OG-N 3.37Å; S122-K125 VanDerWaalsContact OG-N 3.07Å; K125-L129 HydrophobicContact CD-CD1 4.46Å; K125-L129 HydrophobicContact CG-CD1 3.67Å; K125-L129 HydrophobicContact CG-CG 4.33Å; K125-L129 VanDerWaalsContact O-CB 3.28Å; K125-L129 WeakPolarHBondContact O-CB 3.48Å; K125-L129 VanDerWaalsContact O-CG 3.23Å; K125-L129 WeakPolarHBondContact O-CG 3.37Å; K125-L129 PolarHBondContact O-N 3.4Å
126	K	67.4	Low	64.7	Low	110 Å²	110	102.5 Å²	102.5	48%	0.478	55%	0.546	S	S	.	.	H	α-helix	trans	-64.8	-45.8	175.3	-66.2	-175.2	179.5	-173.9	0	112.2	D121 S122 M123 L124 N130 R131	D121-K126 HydrophobicContact CB-CG 4Å; S122-K126 PolarHBondContact O-N 2.96Å; M123-K126 PolarHBondContact O-N 3.47Å; L124-K126 VanDerWaalsContact C-N 3.31Å; L124-K126 PolarHBondContact O-N 2.92Å; K126-N130 PolarHBondContact O-N 2.91Å; K126-R131 PolarHBondContact O-N 3.44Å; K126-R131 VanDerWaalsContact O-N 3.16Å
127	I	70.2	Confident	62.7	Low	117 Å²	117	103 Å²	103	60%	0.6	55%	0.549	S	S	*	.	H	α-helix	trans	-66	-47.2	178.6	-65.7	163.9	0	0	0	110.7	M123 L124 L129 N130	M123-I127 WeakPolarHBondContact O-CD1 3.49Å; M123-I127 VanDerWaalsContact O-CG1 3.23Å; M123-I127 WeakPolarHBondContact O-CG1 3.48Å; M123-I127 PolarHBondContact O-N 3.34Å; L124-I127 PolarHBondContact O-N 3.32Å; I127-L129 PolarHBondContact O-N 3.33Å; I127-N130 PolarHBondContact O-N 3.37Å; I127-N130 VanDerWaalsContact O-N 3.15Å
128	L	70.6	Confident	61.3	Low	142 Å²	142	108.7 Å²	108.7	74%	0.743	57%	0.574	S	S	*	*	H	α-helix	trans	-68.5	-34.1	-176.1	-71.3	172	0	0	0	113.2	L124 N130	L124-L128 VanDerWaalsContact O-CB 3.23Å; L124-L128 WeakPolarHBondContact O-CB 3.34Å; L124-L128 WeakPolarHBondContact O-CG 3.49Å; L124-L128 PolarHBondContact O-N 3.07Å; L128-N130 PolarHBondContact O-N 2.9Å
129	L	72.7	Confident	60.7	Low	114 Å²	114	110.5 Å²	110.5	60%	0.597	58%	0.575	S	S	*	*	T	Hydrogen-bonded Turn	trans	-82.2	3.8	176.5	-65.4	176.2	0	0	0	113	K125 I127 R131	K125-L129 HydrophobicContact CD-CD1 4.46Å; K125-L129 HydrophobicContact CG-CD1 3.67Å; K125-L129 HydrophobicContact CG-CG 4.33Å; K125-L129 VanDerWaalsContact O-CB 3.28Å; K125-L129 WeakPolarHBondContact O-CB 3.48Å; K125-L129 VanDerWaalsContact O-CG 3.23Å; K125-L129 WeakPolarHBondContact O-CG 3.37Å; K125-L129 PolarHBondContact O-N 3.4Å; I127-L129 PolarHBondContact O-N 3.33Å; L129-R131 PolarHBondContact O-N 3.25Å
130	N	53.3	Low	61.2	Low	130 Å²	130	109.3 Å²	109.3	70%	0.695	56%	0.559	S	S	*	*	T	Hydrogen-bonded Turn	trans	47.4	35.5	-174.5	-145.4	27.1	0	0	0	112.1	K126 I127 L128 Q132	K126-N130 PolarHBondContact O-N 2.91Å; I127-N130 PolarHBondContact O-N 3.37Å; I127-N130 VanDerWaalsContact O-N 3.15Å; L128-N130 PolarHBondContact O-N 2.9Å; N130-Q132 PolarHBondContact O-N 2.66Å
131	R	55.4	Low	62.1	Low	116 Å²	116	109.1 Å²	109.1	44%	0.438	54%	0.542	S	S	.	.			trans	-76	71.4	174.3	-161.7	179.5	-165.7	167.3	8.1	106.3	D121 K126 L129 E136	D121-R131 IonicContact OD2-NH1 3.06Å; D121-R131 PolarHBondContact OD2-NH1 3.35Å; K126-R131 PolarHBondContact O-N 3.44Å; K126-R131 VanDerWaalsContact O-N 3.16Å; L129-R131 PolarHBondContact O-N 3.25Å; R131-E136 IonicContact CZ-OE2 3.75Å; R131-E136 IonicContact NE-OE2 3.61Å; R131-E136 IonicContact NH2-OE2 3.13Å; R131-E136 PolarHBondContact NH2-OE2 3.17Å
132	Q	49.4	Very low	63.5	Low	163 Å²	163	107.6 Å²	107.6	76%	0.762	54%	0.535	S	S	*	.			trans	-44.6	140.8	156.3	-95.9	172.8	-26.2	0	0	107.1	N130 S134	N130-Q132 PolarHBondContact O-N 2.66Å; Q132-S134 VanDerWaalsContact C-N 3.26Å; Q132-S134 PolarHBondContact O-N 3.09Å
133	E	47.7	Very low	64.9	Low	176 Å²	176	106.1 Å²	106.1	82%	0.822	52%	0.523	S	S	*	.			trans	-38.8	92.4	-179.4	-66.1	-178.6	154.6	0	0	110
134	S	46.8	Very low	66.2	Low	29 Å²	29	102 Å²	102	20%	0.203	50%	0.502	C	S	.	.			trans	-66.1	152	178.1	41	0	0	0	0	105.8	Q132 E136 T137	Q132-S134 VanDerWaalsContact C-N 3.26Å; Q132-S134 PolarHBondContact O-N 3.09Å; S134-E136 PolarHBondContact O-N 3.06Å; S134-E136 PolarHBondContact OG-OE2 3.23Å; S134-T137 PolarHBondContact O-N 2.88Å; S134-T137 PolarHBondContact O-OG1 3Å
135	P	49.5	Very low	67.4	Low	91 Å²	91	99.2 Å²	99.2	59%	0.591	50%	0.497	S	S	*	.	G	3₁₀ helix	trans	-55.2	-8.3	175.4	19.4	-30.8	0	0	0	113.7	T137	P135-T137 PolarHBondContact O-N 3.34Å
136	E	49.9	Very low	68.7	Low	74 Å²	74	95.1 Å²	95.1	35%	0.346	48%	0.483	S	S	.	.	G	3₁₀ helix	trans	-60	-17.1	164.5	-55.9	-175.8	154.3	0	0	115.1	R131 S134	R131-E136 IonicContact CZ-OE2 3.75Å; R131-E136 IonicContact NE-OE2 3.61Å; R131-E136 IonicContact NH2-OE2 3.13Å; R131-E136 PolarHBondContact NH2-OE2 3.17Å; S134-E136 PolarHBondContact O-N 3.06Å; S134-E136 PolarHBondContact OG-OE2 3.23Å
137	T	51.4	Low	70	Confident	85 Å²	85	89.9 Å²	89.9	52%	0.521	46%	0.46	S	S	.	.	G	3₁₀ helix	trans	-84.8	-22.3	-177.5	-41.7	0	0	0	0	112.5	S134 P135	S134-T137 PolarHBondContact O-N 2.88Å; S134-T137 PolarHBondContact O-OG1 3Å; P135-T137 PolarHBondContact O-N 3.34Å
138	E	59.4	Low	71.2	Confident	183 Å²	183	87.1 Å²	87.1	86%	0.855	45%	0.451	S	S	*	.	S	Bend	trans	-84.7	-11.7	178.8	-66.5	-171.9	158.2	0	0	113.4
139	R	70.4	Confident	72.4	Confident	98 Å²	98	86.7 Å²	86.7	37%	0.37	44%	0.443	S	S	.	.	S	Bend	trans	-89.8	143.4	-175	-62.3	-174.8	-174.5	173.4	4.7	111.5	Q141 Q244	R139-Q141 PolarHBondContact O-N 3.35Å; R139-Q141 VanDerWaalsContact O-N 3.09Å; R139-Q244 VanDerWaalsContact CZ-OE1 3.28Å
140	E	79.8	Confident	73.6	Confident	86 Å²	86	81.2 Å²	81.2	40%	0.402	42%	0.415	S	S	.	.			trans	-61.3	112.8	175.2	-176.9	-179.5	172.2	0	0	109.7	T229 S231 E235	E140-T229 PolarHBondContact OE1-OG1 3.48Å; E140-T229 VanDerWaalsContact OE1-OG1 3.1Å; E140-T229 PolarHBondContact OE2-OG1 3.39Å; E140-S231 VanDerWaalsContact OE2-CB 3.27Å; E140-S231 WeakPolarHBondContact OE2-CB 3.22Å; E140-S231 PolarHBondContact OE2-OG 3.15Å; E140-E235 WeakPolarHBondContact O-CG 3.35Å
141	Q	87.1	Confident	75.8	Confident	93 Å²	93	77.5 Å²	77.5	44%	0.435	39%	0.391	S	S	.	.			trans	-83.4	143.4	174.9	-63.6	-165.5	13.8	0	0	110.5	T52 R139 T143	T52-Q141 HydrophobicContact CG2-CB 3.46Å; T52-Q141 VanDerWaalsContact CG2-CB 3.46Å; T52-Q141 HydrophobicContact CG2-CG 4.3Å; T52-Q141 VanDerWaalsContact CG2-OE1 3.22Å; T52-Q141 PolarHBondContact OG1-OE1 3.22Å; R139-Q141 PolarHBondContact O-N 3.35Å; R139-Q141 VanDerWaalsContact O-N 3.09Å; Q141-T143 PolarHBondContact O-N 3.43Å
142	P	91.9	Very high	77.8	Confident	13 Å²	13	74.9 Å²	74.9	8%	0.084	39%	0.39	C	S	.	.			trans	-59.7	122.6	176.2	-22.6	33.6	0	0	0	110.6	T52 V53 L232 E235 L236	T52-P142 CarbonylContact C-O 3.57Å; T52-P142 WeakPolarHBondContact CA-O 3.37Å; V53-P142 HydrophobicContact CG2-CB 4.21Å; V53-P142 PolarHBondContact N-O 3.33Å; P142-L232 HydrophobicContact CB-CD1 3.8Å; P142-L232 HydrophobicContact CG-CD1 4.47Å; P142-E235 HydrophobicContact CG-CB 3.8Å; P142-L236 HydrophobicContact CB-CB 4.48Å; P142-L236 HydrophobicContact CB-CD1 4.3Å; P142-L236 HydrophobicContact CG-CB 4.23Å
143	T	92.4	Very high	80.1	Confident	34 Å²	34	67.1 Å²	67.1	21%	0.209	35%	0.354	C	S	.	.	B	Isolated β-bridge	trans	-105	155.9	176.8	61.1	0	0	0	0	110.9	Q141 A145 G146 V147	Q141-T143 PolarHBondContact O-N 3.43Å; T143-A145 PolarHBondContact O-N 3.4Å; T143-G146 PolarHBondContact O-N 3.31Å; T143-G146 VanDerWaalsContact O-N 3.16Å; T143-G146 PolarHBondContact OG1-N 3.07Å; T143-V147 WeakPolarHBondContact O-CG2 3.45Å; T143-V147 PolarHBondContact O-N 3.44Å
144	M	91.9	Very high	82.5	Confident	67 Å²	67	58.8 Å²	58.8	33%	0.33	32%	0.315	S	S	.	.	H	α-helix	trans	-55.4	-35.9	173	-83.2	-50.6	-66.4	0	0	112.9	V53 V115 S148	V53-M144 HydrophobicContact CB-SD 4.17Å; V53-M144 HydrophobicContact CG1-CB 4.45Å; V53-M144 HydrophobicContact CG1-CG 3.44Å; V53-M144 VanDerWaalsContact CG1-CG 3.44Å; V53-M144 HydrophobicContact CG1-SD 3.28Å; V53-M144 WeakPolarHBondContact CG1-SD 3.07Å; V53-M144 HydrophobicContact CG2-SD 4.27Å; V115-M144 HydrophobicContact CG2-CE 4.18Å; V115-M144 HydrophobicContact CG2-SD 3.68Å; M144-S148 WeakPolarHBondContact O-CB 3.3Å; M144-S148 PolarHBondContact O-N 2.92Å; M144-S148 PolarHBondContact O-OG 3.12Å
145	A	92.1	Very high	85	Confident	64 Å²	64	63.9 Å²	63.9	53%	0.529	33%	0.333	S	S	.	.	H	α-helix	trans	-65.7	-46.4	177.8	0	0	0	0	0	111.9	T143 S148 K149	T143-A145 PolarHBondContact O-N 3.4Å; A145-S148 PolarHBondContact O-N 3.48Å; A145-K149 WeakPolarHBondContact O-CG 3.12Å; A145-K149 PolarHBondContact O-N 3.43Å; A145-K149 VanDerWaalsContact O-N 3.08Å
146	G	93.4	Very high	87.3	Confident	13 Å²	13	64.6 Å²	64.6	13%	0.134	33%	0.327	C	S	.	.	H	α-helix	trans	-60.9	-48.5	176	0	0	0	0	0	111.9	T143 S148 K149 L150 L232	T143-G146 PolarHBondContact O-N 3.31Å; T143-G146 VanDerWaalsContact O-N 3.16Å; T143-G146 PolarHBondContact OG1-N 3.07Å; G146-S148 VanDerWaalsContact C-N 3.32Å; G146-S148 PolarHBondContact O-N 3.37Å; G146-K149 WeakPolarHBondContact O-CB 3.38Å; G146-K149 PolarHBondContact O-N 3.11Å; G146-L150 PolarHBondContact O-N 3.17Å; G146-L232 VanDerWaalsContact C-CD2 3.45Å; G146-L232 WeakPolarHBondContact O-CD2 3.43Å
147	V	95.4	Very high	89.6	Confident	0 Å²	0	61 Å²	61	0%	0	31%	0.31	C	S	.	.	H	α-helix	trans	-62.8	-39.2	178.5	175.2	0	0	0	0	112	V53 F113 V115 T143 K149 L150 R151 L232 L236	V53-V147 HydrophobicContact CG2-CG2 3.67Å; F113-V147 HydrophobicContact CE2-CG1 3.91Å; V115-V147 HydrophobicContact CB-CG1 4.49Å; V115-V147 HydrophobicContact CG1-CG1 3.86Å; V115-V147 HydrophobicContact CG1-CG2 4.36Å; V115-V147 HydrophobicContact CG2-CG1 3.83Å; T143-V147 WeakPolarHBondContact O-CG2 3.45Å; T143-V147 PolarHBondContact O-N 3.44Å; V147-K149 VanDerWaalsContact C-N 3.34Å; V147-K149 PolarHBondContact O-N 3.01Å; V147-L150 PolarHBondContact O-N 3.45Å; V147-R151 HydrophobicContact CG1-CG 4.34Å; V147-R151 WeakPolarHBondContact O-CG 3.48Å; V147-R151 PolarHBondContact O-N 3.2Å; V147-L232 HydrophobicContact CG2-CD1 4.37Å; V147-L236 HydrophobicContact CG2-CD2 3.98Å
148	S	95.1	Very high	91.8	Very high	59 Å²	59	59.7 Å²	59.7	41%	0.413	30%	0.296	S	S	.	.	H	α-helix	trans	-64.7	-38.2	177.5	-62.2	0	0	0	0	112	M144 A145 G146 C152	M144-S148 WeakPolarHBondContact O-CB 3.3Å; M144-S148 PolarHBondContact O-N 2.92Å; M144-S148 PolarHBondContact O-OG 3.12Å; A145-S148 PolarHBondContact O-N 3.48Å; G146-S148 VanDerWaalsContact C-N 3.32Å; G146-S148 PolarHBondContact O-N 3.37Å; S148-C152 VanDerWaalsContact O-CB 3.26Å; S148-C152 WeakPolarHBondContact O-CB 3.23Å; S148-C152 PolarHBondContact O-N 3Å
149	K	96.3	Very high	93.6	Very high	132 Å²	132	55.1 Å²	55.1	57%	0.574	28%	0.284	S	S	*	.	H	α-helix	trans	-61.8	-46.7	172.5	-72.5	177.1	179.6	-177.3	0	111.4	A145 G146 V147 C152 C153	A145-K149 WeakPolarHBondContact O-CG 3.12Å; A145-K149 PolarHBondContact O-N 3.43Å; A145-K149 VanDerWaalsContact O-N 3.08Å; G146-K149 WeakPolarHBondContact O-CB 3.38Å; G146-K149 PolarHBondContact O-N 3.11Å; V147-K149 VanDerWaalsContact C-N 3.34Å; V147-K149 PolarHBondContact O-N 3.01Å; K149-C152 WeakPolarHBondContact O-CB 3.45Å; K149-C152 PolarHBondContact O-N 3.16Å; K149-C153 PolarHBondContact O-N 3.37Å
150	L	98.1	Very high	94.9	Very high	0 Å²	0	50.7 Å²	50.7	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-59.2	-49.9	177	173	59.7	0	0	0	111.8	I103 F113 G146 V147 C152 C153 L154 I228 L236 F237	I103-L150 HydrophobicContact CD1-CD1 4.42Å; I103-L150 HydrophobicContact CG1-CD1 4Å; I103-L150 HydrophobicContact CG2-CD1 4.07Å; F113-L150 HydrophobicContact CE1-CD2 4.34Å; F113-L150 HydrophobicContact CZ-CD2 3.75Å; F113-L150 HydrophobicContact CZ-CG 4.16Å; G146-L150 PolarHBondContact O-N 3.17Å; V147-L150 PolarHBondContact O-N 3.45Å; L150-C152 VanDerWaalsContact C-N 3.32Å; L150-C152 PolarHBondContact O-N 3.05Å; L150-C153 WeakPolarHBondContact O-CB 3.39Å; L150-C153 PolarHBondContact O-N 3.45Å; L150-C153 VanDerWaalsContact O-N 3.16Å; L150-L154 HydrophobicContact CD1-CD1 4.36Å; L150-L154 HydrophobicContact CD1-CG 4.29Å; L150-L154 HydrophobicContact CG-CD1 4.4Å; L150-L154 WeakPolarHBondContact O-CG 3.45Å; L150-L154 PolarHBondContact O-N 3.27Å; L150-I228 HydrophobicContact CB-CD1 4.28Å; L150-I228 HydrophobicContact CD1-CD1 3.89Å; L150-I228 HydrophobicContact CD1-CG2 4.39Å; L150-L236 HydrophobicContact CD2-CD2 4.35Å; L150-F237 HydrophobicContact CD2-CE2 3.66Å; L150-F237 HydrophobicContact CD2-CZ 3.96Å
151	R	97.8	Very high	95.7	Very high	52 Å²	52	52.7 Å²	52.7	20%	0.196	28%	0.281	C	S	.	.	H	α-helix	trans	-61.3	-39.4	177.1	-74.7	174.3	161.7	-173.3	-29.4	112.7	F113 D114 V147 C153 L154 K155	F113-R151 HydrophobicContact CE2-CG 4.31Å; F113-R151 HydrophobicContact CZ-CG 3.97Å; F113-R151 PolarHBondContact O-NE 2.69Å; F113-R151 PolarHBondContact O-NH2 2.88Å; D114-R151 VanDerWaalsContact CA-NH2 3.28Å; D114-R151 IonicContact OD1-CZ 3.55Å; D114-R151 IonicContact OD1-NH2 2.99Å; D114-R151 PolarHBondContact OD1-NH2 2.75Å; V147-R151 HydrophobicContact CG1-CG 4.34Å; V147-R151 WeakPolarHBondContact O-CG 3.48Å; V147-R151 PolarHBondContact O-N 3.2Å; R151-C153 VanDerWaalsContact C-N 3.33Å; R151-L154 PolarHBondContact O-N 2.82Å; R151-K155 WeakPolarHBondContact O-CB 3.41Å; R151-K155 WeakPolarHBondContact O-CG 3.4Å; R151-K155 PolarHBondContact O-N 2.86Å
152	C	97.6	Very high	96.2	Very high	60 Å²	60	48.9 Å²	48.9	41%	0.405	26%	0.264	S	S	.	.	H	α-helix	trans	-61.1	-44.6	175.1	-174.3	0	0	0	0	111	S148 K149 L150 K155 K156	S148-C152 VanDerWaalsContact O-CB 3.26Å; S148-C152 WeakPolarHBondContact O-CB 3.23Å; S148-C152 PolarHBondContact O-N 3Å; K149-C152 WeakPolarHBondContact O-CB 3.45Å; K149-C152 PolarHBondContact O-N 3.16Å; L150-C152 VanDerWaalsContact C-N 3.32Å; L150-C152 PolarHBondContact O-N 3.05Å; C152-K155 PolarHBondContact O-N 3.44Å; C152-K156 WeakPolarHBondContact O-CG 3.39Å; C152-K156 PolarHBondContact O-N 2.89Å
153	C	98.1	Very high	96.5	Very high	1 Å²	1	49.7 Å²	49.7	1%	0.007	27%	0.269	C	S	.	.	H	α-helix	trans	-59.2	-49.3	175.4	-177	0	0	0	0	111.8	K149 L150 R151 K155 K156 F157 M224 I228	K149-C153 PolarHBondContact O-N 3.37Å; L150-C153 WeakPolarHBondContact O-CB 3.39Å; L150-C153 PolarHBondContact O-N 3.45Å; L150-C153 VanDerWaalsContact O-N 3.16Å; R151-C153 VanDerWaalsContact C-N 3.33Å; C153-K155 PolarHBondContact O-N 3.01Å; C153-K156 WeakPolarHBondContact O-CB 3.49Å; C153-K156 PolarHBondContact O-N 3.47Å; C153-K156 VanDerWaalsContact O-N 3.15Å; C153-F157 WeakPolarHBondContact O-CD2 3.34Å; C153-F157 PolarHBondContact O-N 2.91Å; C153-M224 HydrophobicContact CB-CE 4.37Å; C153-I228 HydrophobicContact CB-CD1 3.69Å
154	L	98.4	Very high	96.7	Very high	1 Å²	1	52.8 Å²	52.8	1%	0.005	29%	0.29	C	S	.	.	H	α-helix	trans	-58.9	-46.1	177.2	-67.5	175	0	0	0	112.2	I103 L106 A107 F113 L150 R151 K156 F157 W158	I103-L154 HydrophobicContact CG2-CD2 3.95Å; L106-L154 HydrophobicContact CB-CD2 3.91Å; A107-L154 HydrophobicContact CB-CD2 3.93Å; F113-L154 HydrophobicContact CE1-CD1 3.74Å; L150-L154 HydrophobicContact CD1-CD1 4.36Å; L150-L154 HydrophobicContact CD1-CG 4.29Å; L150-L154 HydrophobicContact CG-CD1 4.4Å; L150-L154 WeakPolarHBondContact O-CG 3.45Å; L150-L154 PolarHBondContact O-N 3.27Å; R151-L154 PolarHBondContact O-N 2.82Å; L154-K156 VanDerWaalsContact C-N 3.28Å; L154-K156 PolarHBondContact O-N 3.47Å; L154-F157 PolarHBondContact O-N 2.86Å; L154-F157 VanDerWaalsContact O-N 3.12Å; L154-W158 HydrophobicContact CB-CH2 4.06Å; L154-W158 HydrophobicContact CB-CZ2 3.96Å; L154-W158 HydrophobicContact CB-CZ3 4.39Å; L154-W158 HydrophobicContact CD1-CZ2 4.45Å; L154-W158 VanDerWaalsContact O-CG 3.3Å; L154-W158 PolarHBondContact O-N 3.23Å
155	K	98.2	Very high	96.9	Very high	135 Å²	135	55.6 Å²	55.6	59%	0.587	30%	0.301	S	S	*	.	H	α-helix	trans	-59.8	-37.2	176.6	-73.6	178.7	-179.1	-173.7	0	112.7	R151 C152 C153 W158 S159	R151-K155 WeakPolarHBondContact O-CB 3.41Å; R151-K155 WeakPolarHBondContact O-CG 3.4Å; R151-K155 PolarHBondContact O-N 2.86Å; C152-K155 PolarHBondContact O-N 3.44Å; C153-K155 PolarHBondContact O-N 3.01Å; K155-W158 HydrophobicContact CB-CE3 4.46Å; K155-W158 HydrophobicContact CG-CE3 3.96Å; K155-W158 HydrophobicContact CG-CZ3 3.96Å; K155-S159 WeakPolarHBondContact O-CB 3.49Å; K155-S159 PolarHBondContact O-N 3.32Å
156	K	98.1	Very high	97.2	Very high	106 Å²	106	52.6 Å²	52.6	46%	0.461	28%	0.275	S	S	.	.	H	α-helix	trans	-64.6	-45.4	174.5	-71.5	-69.9	-174.7	179.9	0	111.1	C152 C153 L154 S159 L160 T221 M224	C152-K156 WeakPolarHBondContact O-CG 3.39Å; C152-K156 PolarHBondContact O-N 2.89Å; C153-K156 WeakPolarHBondContact O-CB 3.49Å; C153-K156 PolarHBondContact O-N 3.47Å; C153-K156 VanDerWaalsContact O-N 3.15Å; L154-K156 VanDerWaalsContact C-N 3.28Å; L154-K156 PolarHBondContact O-N 3.47Å; K156-S159 PolarHBondContact O-N 3.49Å; K156-S159 PolarHBondContact O-OG 3.41Å; K156-L160 PolarHBondContact O-N 3.21Å; K156-T221 HydrophobicContact CB-CG2 3.78Å; K156-M224 HydrophobicContact CB-SD 4.21Å; K156-M224 HydrophobicContact CG-CE 4.13Å; K156-M224 HydrophobicContact CG-SD 3.96Å
157	F	98.4	Very high	97.5	Very high	0 Å²	0	52.4 Å²	52.4	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-61.9	-43.3	174.7	-81.4	-69.8	0	0	0	113.3	L104 A107 C153 L154 S159 L160 L162 L170 T221 L225	L104-F157 HydrophobicContact CD2-CD1 4.14Å; L104-F157 HydrophobicContact CD2-CE1 3.5Å; L104-F157 HydrophobicContact CD2-CE2 4.01Å; L104-F157 HydrophobicContact CD2-CZ 3.41Å; L104-F157 VanDerWaalsContact CD2-CZ 3.41Å; A107-F157 HydrophobicContact CB-CB 3.69Å; A107-F157 HydrophobicContact CB-CG 4.18Å; C153-F157 WeakPolarHBondContact O-CD2 3.34Å; C153-F157 PolarHBondContact O-N 2.91Å; L154-F157 PolarHBondContact O-N 2.86Å; L154-F157 VanDerWaalsContact O-N 3.12Å; F157-S159 VanDerWaalsContact C-N 3.26Å; F157-S159 PolarHBondContact O-N 3Å; F157-L160 HydrophobicContact CD1-CD1 4.23Å; F157-L160 WeakPolarHBondContact O-CB 3.42Å; F157-L160 PolarHBondContact O-N 2.86Å; F157-L162 HydrophobicContact CD1-CD1 3.96Å; F157-L162 HydrophobicContact CE1-CD1 4.32Å; F157-L170 HydrophobicContact CE1-CD2 3.81Å; F157-L170 HydrophobicContact CZ-CD2 4.49Å; F157-T221 HydrophobicContact CD1-CG2 4.06Å; F157-T221 HydrophobicContact CD2-CG2 4.08Å; F157-T221 HydrophobicContact CE1-CG2 3.94Å; F157-T221 HydrophobicContact CE2-CG2 3.98Å; F157-T221 HydrophobicContact CG-CG2 4.12Å; F157-T221 HydrophobicContact CZ-CG2 3.91Å; F157-L225 HydrophobicContact CE2-CD2 3.78Å; F157-L225 HydrophobicContact CE2-CG 4.14Å; F157-L225 HydrophobicContact CZ-CD1 4.21Å; F157-L225 HydrophobicContact CZ-CD2 4.26Å; F157-L225 HydrophobicContact CZ-CG 4.24Å
158	W	98.4	Very high	97.6	Very high	57 Å²	57	54.2 Å²	54.2	22%	0.216	29%	0.286	C	S	.	.	H	α-helix	trans	-61.2	-36.4	175.3	-61.4	-31.2	0	0	0	112.3	A107 H110 D112 L154 K155 L160 D161	A107-W158 PolarHBondContact O-NE1 3.01Å; A107-W158 VanDerWaalsContact O-NE1 3.09Å; H110-W158 AromaticContact CE1-CD1 3.58Å; H110-W158 AromaticContact ND1-CD1 3.4Å; H110-W158 AromaticContact ND1-CG 3.95Å; H110-W158 AromaticContact ND1-NE1 3.59Å; D112-W158 HydrophobicContact CB-CH2 4.12Å; L154-W158 HydrophobicContact CB-CH2 4.06Å; L154-W158 HydrophobicContact CB-CZ2 3.96Å; L154-W158 HydrophobicContact CB-CZ3 4.39Å; L154-W158 HydrophobicContact CD1-CZ2 4.45Å; L154-W158 VanDerWaalsContact O-CG 3.3Å; L154-W158 PolarHBondContact O-N 3.23Å; K155-W158 HydrophobicContact CB-CE3 4.46Å; K155-W158 HydrophobicContact CG-CE3 3.96Å; K155-W158 HydrophobicContact CG-CZ3 3.96Å; W158-L160 PolarHBondContact O-N 3.44Å; W158-D161 PolarHBondContact O-N 2.87Å
159	S	97.8	Very high	97.8	Very high	86 Å²	86	55.6 Å²	55.6	60%	0.601	28%	0.283	S	S	*	.	H	α-helix	trans	-69.7	-18.4	176.4	75.3	0	0	0	0	114.2	K155 K156 F157 D161	K155-S159 WeakPolarHBondContact O-CB 3.49Å; K155-S159 PolarHBondContact O-N 3.32Å; K156-S159 PolarHBondContact O-N 3.49Å; K156-S159 PolarHBondContact O-OG 3.41Å; F157-S159 VanDerWaalsContact C-N 3.26Å; F157-S159 PolarHBondContact O-N 3Å; S159-D161 VanDerWaalsContact C-N 3.33Å
160	L	96.8	Very high	97.9	Very high	5 Å²	5	49.4 Å²	49.4	3%	0.026	26%	0.256	C	S	.	.	H	α-helix	trans	-77.5	-22.3	174.6	-67.6	176	0	0	0	112.5	K156 F157 W158 L162 R214 R217 I218 T221	K156-L160 PolarHBondContact O-N 3.21Å; F157-L160 HydrophobicContact CD1-CD1 4.23Å; F157-L160 WeakPolarHBondContact O-CB 3.42Å; F157-L160 PolarHBondContact O-N 2.86Å; W158-L160 PolarHBondContact O-N 3.44Å; L160-L162 HydrophobicContact CB-CD2 3.67Å; L160-L162 HydrophobicContact CB-CG 3.9Å; L160-L162 HydrophobicContact CD1-CD1 4.49Å; L160-L162 HydrophobicContact CD1-CD2 4.18Å; L160-L162 HydrophobicContact CD1-CG 4.46Å; L160-R214 VanDerWaalsContact O-CZ 3.32Å; L160-R214 PolarHBondContact O-NH1 3.4Å; L160-R214 PolarHBondContact O-NH2 2.89Å; L160-R217 HydrophobicContact CD2-CG 3.89Å; L160-I218 HydrophobicContact CD1-CG1 4.3Å; L160-T221 HydrophobicContact CD1-CG2 3.9Å
161	D	96.1	Very high	97.9	Very high	128 Å²	128	50.3 Å²	50.3	68%	0.684	26%	0.259	S	S	*	.			trans	49.3	61.5	-175.5	-168.8	33.2	0	0	0	111	W158 S159 R214	W158-D161 PolarHBondContact O-N 2.87Å; S159-D161 VanDerWaalsContact C-N 3.33Å; D161-R214 PolarHBondContact O-NH2 3.43Å
162	L	97.9	Very high	97.9	Very high	14 Å²	14	48.2 Å²	48.2	7%	0.073	25%	0.254	C	S	.	.			trans	-75.8	130.8	-177.4	-59.7	-175.7	0	0	0	110.5	F157 L160 E166 Y167 L170 I218	F157-L162 HydrophobicContact CD1-CD1 3.96Å; F157-L162 HydrophobicContact CE1-CD1 4.32Å; L160-L162 HydrophobicContact CB-CD2 3.67Å; L160-L162 HydrophobicContact CB-CG 3.9Å; L160-L162 HydrophobicContact CD1-CD1 4.49Å; L160-L162 HydrophobicContact CD1-CD2 4.18Å; L160-L162 HydrophobicContact CD1-CG 4.46Å; L162-E166 WeakPolarHBondContact CA-OE2 3.26Å; L162-E166 HydrophobicContact CB-CB 4.27Å; L162-E166 HydrophobicContact CD2-CB 4.41Å; L162-Y167 HydrophobicContact CB-CD2 3.7Å; L162-Y167 HydrophobicContact CB-CE1 4.43Å; L162-Y167 HydrophobicContact CB-CE2 3.5Å; L162-Y167 HydrophobicContact CB-CG 4.26Å; L162-Y167 HydrophobicContact CD1-CD1 4.15Å; L162-Y167 HydrophobicContact CD1-CE1 3.88Å; L162-Y167 HydrophobicContact CD1-CE2 4.45Å; L162-Y167 HydrophobicContact CG-CE2 4.45Å; L162-Y167 WeakPolarHBondContact O-CE2 3.02Å; L162-L170 HydrophobicContact CD1-CD2 4.1Å; L162-I218 HydrophobicContact CD2-CD1 3.73Å; L162-I218 HydrophobicContact CD2-CG1 3.76Å
163	S	97.5	Very high	98	Very high	29 Å²	29	46 Å²	46	20%	0.203	24%	0.239	C	C	.	.			trans	-66.5	159.2	171	68.1	0	0	0	0	111.6	K165 E166 Y167	S163-K165 PolarHBondContact O-N 2.86Å; S163-K165 VanDerWaalsContact O-N 3.14Å; S163-E166 PolarHBondContact N-OE2 3.04Å; S163-E166 PolarHBondContact O-N 3.18Å; S163-E166 VanDerWaalsContact O-N 3.12Å; S163-E166 VanDerWaalsContact OG-CG 3.32Å; S163-E166 WeakPolarHBondContact OG-CG 3.27Å; S163-E166 PolarHBondContact OG-N 2.88Å; S163-E166 PolarHBondContact OG-OE2 3.1Å; S163-Y167 PolarHBondContact O-N 3.29Å
164	P	97.4	Very high	98	Very high	100 Å²	100	47.1 Å²	47.1	65%	0.649	25%	0.246	S	C	*	.	H	α-helix	trans	-55.7	-32.1	175	-27.7	35.6	0	0	0	113.8	A168	P164-A168 WeakPolarHBondContact O-CB 3.43Å; P164-A168 PolarHBondContact O-N 3.14Å
165	K	97.2	Very high	97.9	Very high	126 Å²	126	47.1 Å²	47.1	55%	0.548	25%	0.246	S	C	.	.	H	α-helix	trans	-71.1	-45.3	176.5	-69.3	-173.9	178.5	-177.6	0	111.8	S163 Y167 A168 Y169 V203	S163-K165 PolarHBondContact O-N 2.86Å; S163-K165 VanDerWaalsContact O-N 3.14Å; K165-Y167 VanDerWaalsContact C-N 3.32Å; K165-Y167 PolarHBondContact O-N 3.34Å; K165-A168 WeakPolarHBondContact O-CB 3.43Å; K165-A168 PolarHBondContact O-N 3Å; K165-A168 VanDerWaalsContact O-N 3.14Å; K165-Y169 HydrophobicContact CB-CE2 4.33Å; K165-Y169 WeakPolarHBondContact O-CD2 3.21Å; K165-Y169 PolarHBondContact O-N 3.18Å; K165-V203 HydrophobicContact CB-CG2 3.98Å; K165-V203 HydrophobicContact CD-CG2 4.04Å
166	E	98.3	Very high	97.9	Very high	0 Å²	0	41.2 Å²	41.2	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-59.9	-43	175.6	-72.3	168.2	130	0	0	111.1	L162 S163 A168 Y169 L170 L200 V203 V204 H208 R214	L162-E166 WeakPolarHBondContact CA-OE2 3.26Å; L162-E166 HydrophobicContact CB-CB 4.27Å; L162-E166 HydrophobicContact CD2-CB 4.41Å; S163-E166 PolarHBondContact N-OE2 3.04Å; S163-E166 PolarHBondContact O-N 3.18Å; S163-E166 VanDerWaalsContact O-N 3.12Å; S163-E166 VanDerWaalsContact OG-CG 3.32Å; S163-E166 WeakPolarHBondContact OG-CG 3.27Å; S163-E166 PolarHBondContact OG-N 2.88Å; S163-E166 PolarHBondContact OG-OE2 3.1Å; E166-A168 PolarHBondContact O-N 2.87Å; E166-Y169 PolarHBondContact O-N 3.35Å; E166-L170 WeakPolarHBondContact O-CB 3.44Å; E166-L170 PolarHBondContact O-N 3.28Å; E166-L200 HydrophobicContact CB-CD1 4.11Å; E166-L200 HydrophobicContact CG-CD1 4.22Å; E166-V203 HydrophobicContact CG-CG1 3.8Å; E166-V204 HydrophobicContact CG-CG2 4.23Å; E166-V204 WeakPolarHBondContact OE1-CG2 3.48Å; E166-H208 IonicContact OE1-CD2 3.84Å; E166-H208 IonicContact OE1-NE2 3.7Å; E166-R214 IonicContact OE1-CZ 2.76Å; E166-R214 IonicContact OE1-NE 3.95Å; E166-R214 PolarHBondContact OE1-NE 2.86Å; E166-R214 IonicContact OE1-NH2 3.76Å; E166-R214 PolarHBondContact OE1-NH2 2.97Å; E166-R214 VanDerWaalsContact OE1-NH2 3.13Å; E166-R214 IonicContact OE2-CZ 3.63Å; E166-R214 IonicContact OE2-NH2 2.75Å; E166-R214 PolarHBondContact OE2-NH2 3.16Å
167	Y	98.6	Very high	97.9	Very high	9 Å²	9	38 Å²	38	4%	0.035	21%	0.208	C	C	.	.	H	α-helix	trans	-59.7	-43.4	172.6	-87.5	-64.7	0	0	0	112.7	A107 Q108 L162 S163 K165 L170 K171	A107-Y167 HydrophobicContact CB-CE1 4.34Å; Q108-Y167 HydrophobicContact CB-CD1 4.04Å; Q108-Y167 HydrophobicContact CB-CD2 3.98Å; Q108-Y167 HydrophobicContact CB-CE1 3.92Å; Q108-Y167 HydrophobicContact CB-CE2 3.82Å; Q108-Y167 HydrophobicContact CB-CG 4.08Å; Q108-Y167 HydrophobicContact CG-CD1 4.49Å; Q108-Y167 HydrophobicContact CG-CD2 3.73Å; Q108-Y167 HydrophobicContact CG-CE2 3.92Å; Q108-Y167 HydrophobicContact CG-CG 4.02Å; Q108-Y167 PolarHBondContact N-OH 3.2Å; L162-Y167 HydrophobicContact CB-CD2 3.7Å; L162-Y167 HydrophobicContact CB-CE1 4.43Å; L162-Y167 HydrophobicContact CB-CE2 3.5Å; L162-Y167 HydrophobicContact CB-CG 4.26Å; L162-Y167 HydrophobicContact CD1-CD1 4.15Å; L162-Y167 HydrophobicContact CD1-CE1 3.88Å; L162-Y167 HydrophobicContact CD1-CE2 4.45Å; L162-Y167 HydrophobicContact CG-CE2 4.45Å; L162-Y167 WeakPolarHBondContact O-CE2 3.02Å; S163-Y167 PolarHBondContact O-N 3.29Å; K165-Y167 VanDerWaalsContact C-N 3.32Å; K165-Y167 PolarHBondContact O-N 3.34Å; Y167-L170 PolarHBondContact O-N 2.97Å; Y167-K171 WeakPolarHBondContact O-CB 3.39Å; Y167-K171 VanDerWaalsContact O-CG 3.25Å; Y167-K171 WeakPolarHBondContact O-CG 3.44Å; Y167-K171 PolarHBondContact O-N 2.93Å
168	A	98.2	Very high	97.9	Very high	38 Å²	38	39.6 Å²	39.6	31%	0.314	22%	0.218	S	C	.	.	H	α-helix	trans	-62.1	-46.9	-179.5	0	0	0	0	0	112	P164 K165 E166 K171 G172	P164-A168 WeakPolarHBondContact O-CB 3.43Å; P164-A168 PolarHBondContact O-N 3.14Å; K165-A168 WeakPolarHBondContact O-CB 3.43Å; K165-A168 PolarHBondContact O-N 3Å; K165-A168 VanDerWaalsContact O-N 3.14Å; E166-A168 PolarHBondContact O-N 2.87Å; A168-K171 PolarHBondContact O-N 3.36Å; A168-G172 PolarHBondContact O-N 3.3Å
169	Y	98.4	Very high	97.8	Very high	89 Å²	89	43.4 Å²	43.4	35%	0.349	24%	0.243	S	C	.	.	H	α-helix	trans	-69.4	-40	177.8	-62.9	-58.8	0	0	0	112.1	K165 E166 K171 G172 T173 A199 V203	K165-Y169 HydrophobicContact CB-CE2 4.33Å; K165-Y169 WeakPolarHBondContact O-CD2 3.21Å; K165-Y169 PolarHBondContact O-N 3.18Å; E166-Y169 PolarHBondContact O-N 3.35Å; Y169-K171 VanDerWaalsContact C-N 3.33Å; Y169-K171 PolarHBondContact O-N 3.46Å; Y169-G172 CarbonylContact O-C 3.58Å; Y169-G172 VanDerWaalsContact O-CA 3.32Å; Y169-G172 WeakPolarHBondContact O-CA 3.41Å; Y169-G172 PolarHBondContact O-N 3.06Å; Y169-T173 WeakPolarHBondContact O-CG2 3.47Å; Y169-T173 PolarHBondContact O-N 3.2Å; Y169-A199 HydrophobicContact CD1-CB 3.51Å; Y169-A199 HydrophobicContact CD2-CB 4.43Å; Y169-A199 HydrophobicContact CE1-CB 3.39Å; Y169-A199 HydrophobicContact CE2-CB 4.34Å; Y169-A199 HydrophobicContact CG-CB 4.06Å; Y169-V203 HydrophobicContact CD2-CB 4.26Å; Y169-V203 HydrophobicContact CD2-CG1 3.8Å; Y169-V203 HydrophobicContact CE2-CB 4.03Å; Y169-V203 HydrophobicContact CE2-CG1 4.08Å; Y169-V203 HydrophobicContact CE2-CG2 4.35Å
170	L	98.6	Very high	97.8	Very high	1 Å²	1	40 Å²	40	1%	0.005	22%	0.219	C	C	.	.	H	α-helix	trans	-60	-42.2	174.6	-178.2	61.3	0	0	0	112	L104 F157 L162 E166 Y167 G172 T173 T174 L200 I218 A222	L104-L170 HydrophobicContact CD1-CD2 4.3Å; L104-L170 HydrophobicContact CD1-CG 4.11Å; L104-L170 HydrophobicContact CD2-CD2 3.69Å; L104-L170 HydrophobicContact CD2-CG 4.39Å; F157-L170 HydrophobicContact CE1-CD2 3.81Å; F157-L170 HydrophobicContact CZ-CD2 4.49Å; L162-L170 HydrophobicContact CD1-CD2 4.1Å; E166-L170 WeakPolarHBondContact O-CB 3.44Å; E166-L170 PolarHBondContact O-N 3.28Å; Y167-L170 PolarHBondContact O-N 2.97Å; L170-G172 VanDerWaalsContact C-N 3.3Å; L170-G172 PolarHBondContact O-N 3.27Å; L170-T173 PolarHBondContact O-N 3.24Å; L170-T173 PolarHBondContact O-OG1 2.92Å; L170-T174 PolarHBondContact O-N 2.67Å; L170-T174 PolarHBondContact O-OG1 3.4Å; L170-L200 HydrophobicContact CB-CD2 4.43Å; L170-L200 HydrophobicContact CD1-CD2 4.35Å; L170-I218 HydrophobicContact CD1-CG2 4.04Å; L170-I218 HydrophobicContact CD2-CG2 4.01Å; L170-A222 HydrophobicContact CD1-CB 3.87Å
171	K	98.6	Very high	97.6	Very high	19 Å²	19	44.6 Å²	44.6	8%	0.083	25%	0.249	C	C	.	.	H	α-helix	trans	-60.2	-41.3	171.3	-73.6	175.4	179.1	177.6	0	111.2	F75 L101 L104 Y167 A168 Y169 T174 I175	F75-K171 HydrophobicContact CD1-CB 4.34Å; F75-K171 HydrophobicContact CD1-CD 4.35Å; F75-K171 HydrophobicContact CE1-CB 3.59Å; F75-K171 HydrophobicContact CE1-CD 4.23Å; F75-K171 HydrophobicContact CZ-CB 3.98Å; F75-K171 HydrophobicContact CZ-CD 4.46Å; L101-K171 HydrophobicContact CD2-CB 3.72Å; L101-K171 HydrophobicContact CD2-CG 3.75Å; L104-K171 HydrophobicContact CB-CG 4.44Å; L104-K171 HydrophobicContact CD1-CG 4Å; Y167-K171 WeakPolarHBondContact O-CB 3.39Å; Y167-K171 VanDerWaalsContact O-CG 3.25Å; Y167-K171 WeakPolarHBondContact O-CG 3.44Å; Y167-K171 PolarHBondContact O-N 2.93Å; A168-K171 PolarHBondContact O-N 3.36Å; Y169-K171 VanDerWaalsContact C-N 3.33Å; Y169-K171 PolarHBondContact O-N 3.46Å; K171-T174 WeakPolarHBondContact O-CB 3.19Å; K171-T174 PolarHBondContact O-N 3.36Å; K171-T174 VanDerWaalsContact O-N 3.16Å; K171-I175 VanDerWaalsContact O-CG1 3.29Å; K171-I175 WeakPolarHBondContact O-CG1 3.39Å; K171-I175 PolarHBondContact O-N 3.44Å
172	G	98.3	Very high	97.5	Very high	8 Å²	8	47.7 Å²	47.7	8%	0.082	26%	0.259	C	S	.	.	H	α-helix	trans	-54.8	-51.2	172	0	0	0	0	0	112.8	A168 Y169 L170 T174 I175 F176	A168-G172 PolarHBondContact O-N 3.3Å; Y169-G172 CarbonylContact O-C 3.58Å; Y169-G172 VanDerWaalsContact O-CA 3.32Å; Y169-G172 WeakPolarHBondContact O-CA 3.41Å; Y169-G172 PolarHBondContact O-N 3.06Å; L170-G172 VanDerWaalsContact C-N 3.3Å; L170-G172 PolarHBondContact O-N 3.27Å; G172-T174 PolarHBondContact O-N 3.43Å; G172-I175 PolarHBondContact O-N 3.08Å; G172-F176 VanDerWaalsContact O-CD2 3.23Å; G172-F176 WeakPolarHBondContact O-CD2 3.33Å; G172-F176 PolarHBondContact O-N 2.86Å
173	T	98.1	Very high	97.5	Very high	13 Å²	13	48.2 Å²	48.2	8%	0.08	26%	0.261	C	S	.	.	H	α-helix	trans	-60.6	-29.2	177.6	68.1	0	0	0	0	113.1	Y169 L170 Q193 A196 Q197	Y169-T173 WeakPolarHBondContact O-CG2 3.47Å; Y169-T173 PolarHBondContact O-N 3.2Å; L170-T173 PolarHBondContact O-N 3.24Å; L170-T173 PolarHBondContact O-OG1 2.92Å; T173-Q193 PolarHBondContact O-NE2 3.28Å; T173-A196 HydrophobicContact CG2-CB 3.79Å; T173-Q197 HydrophobicContact CG2-CB 4.22Å; T173-Q197 HydrophobicContact CG2-CG 3.47Å; T173-Q197 VanDerWaalsContact CG2-CG 3.47Å
174	T	97.9	Very high	97.5	Very high	26 Å²	26	54.2 Å²	54.2	16%	0.16	29%	0.287	C	S	.	.	H	α-helix	trans	-82.1	-34.6	-179.7	-56.5	0	0	0	0	112	C97 P100 L101 L170 K171 G172	C97-T174 HydrophobicContact CB-CG2 4.32Å; C97-T174 WeakPolarHBondContact CB-O 3.35Å; P100-T174 HydrophobicContact CB-CG2 3.62Å; L101-T174 HydrophobicContact CD2-CG2 4Å; L101-T174 HydrophobicContact CG-CG2 4.18Å; L170-T174 PolarHBondContact O-N 2.67Å; L170-T174 PolarHBondContact O-OG1 3.4Å; K171-T174 WeakPolarHBondContact O-CB 3.19Å; K171-T174 PolarHBondContact O-N 3.36Å; K171-T174 VanDerWaalsContact O-N 3.16Å; G172-T174 PolarHBondContact O-N 3.43Å
175	I	98.1	Very high	97.5	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-70.1	-50.5	177.2	-72.3	161.7	0	0	0	110.4	F75 M76 L79 F82 L93 L101 K171 G172 N177	F75-I175 HydrophobicContact CD1-CD1 3.76Å; F75-I175 HydrophobicContact CE1-CD1 3.52Å; M76-I175 HydrophobicContact CE-CG1 4.44Å; M76-I175 HydrophobicContact CE-CG2 4.43Å; M76-I175 HydrophobicContact CG-CD1 3.82Å; M76-I175 HydrophobicContact CG-CG1 4.13Å; L79-I175 HydrophobicContact CD1-CD1 3.55Å; F82-I175 HydrophobicContact CD2-CG2 3.75Å; F82-I175 HydrophobicContact CE2-CG2 4.04Å; L93-I175 WeakPolarHBondContact CD2-O 3.43Å; L101-I175 HydrophobicContact CD1-CD1 4.14Å; L101-I175 HydrophobicContact CD1-CG1 3.52Å; L101-I175 HydrophobicContact CD2-CD1 4.37Å; L101-I175 HydrophobicContact CD2-CG1 3.97Å; L101-I175 HydrophobicContact CG-CG1 4.3Å; K171-I175 VanDerWaalsContact O-CG1 3.29Å; K171-I175 WeakPolarHBondContact O-CG1 3.39Å; K171-I175 PolarHBondContact O-N 3.44Å; G172-I175 PolarHBondContact O-N 3.08Å; I175-N177 VanDerWaalsContact C-N 3.34Å; I175-N177 PolarHBondContact O-N 2.96Å; I175-N177 VanDerWaalsContact O-N 3.08Å
176	F	98.4	Very high	97.6	Very high	12 Å²	12	45.6 Å²	45.6	5%	0.053	25%	0.249	C	C	.	.			trans	-87.5	78.5	-174.6	-57.1	-59	0	0	0	109.1	L79 A81 F82 L85 G172 V189 L192 Q193	L79-F176 HydrophobicContact CD1-CE2 4.36Å; L79-F176 HydrophobicContact CD1-CZ 4.1Å; A81-F176 HydrophobicContact CB-CZ 4.21Å; F82-F176 HydrophobicContact CB-CE1 4.35Å; F82-F176 HydrophobicContact CB-CZ 4.47Å; F82-F176 HydrophobicContact CD2-CE1 4.25Å; L85-F176 HydrophobicContact CD1-CE1 4.41Å; G172-F176 VanDerWaalsContact O-CD2 3.23Å; G172-F176 WeakPolarHBondContact O-CD2 3.33Å; G172-F176 PolarHBondContact O-N 2.86Å; F176-V189 HydrophobicContact CB-CG1 4.07Å; F176-L192 HydrophobicContact CB-CB 3.97Å; F176-L192 HydrophobicContact CD1-CB 3.93Å; F176-L192 HydrophobicContact CD1-CD1 3.68Å; F176-L192 HydrophobicContact CD1-CG 4.48Å; F176-L192 HydrophobicContact CD2-CB 3.75Å; F176-L192 HydrophobicContact CE1-CB 4.39Å; F176-L192 HydrophobicContact CE1-CD1 3.59Å; F176-L192 HydrophobicContact CE2-CB 4.22Å; F176-L192 HydrophobicContact CG-CB 3.59Å; F176-L192 HydrophobicContact CG-CD1 4.24Å; F176-L192 HydrophobicContact CZ-CD1 4.05Å; F176-Q193 HydrophobicContact CB-CB 4.22Å; F176-Q193 WeakPolarHBondContact O-CB 3.32Å; F176-Q193 WeakPolarHBondContact O-CG 3.47Å; F176-Q193 PolarHBondContact O-NE2 3.24Å
177	N	97.4	Very high	97.5	Very high	39 Å²	39	52.6 Å²	52.6	21%	0.209	29%	0.286	C	S	.	.			trans	-102.7	107.9	177.5	-178.5	13.7	0	0	0	110.4	I175 D179 V180	I175-N177 VanDerWaalsContact C-N 3.34Å; I175-N177 PolarHBondContact O-N 2.96Å; I175-N177 VanDerWaalsContact O-N 3.08Å; N177-D179 PolarHBondContact O-N 3.32Å; N177-D179 WeakPolarHBondContact OD1-CB 3.3Å; N177-D179 PolarHBondContact OD1-N 3.42Å; N177-D179 VanDerWaalsContact OD1-N 3.08Å; N177-V180 HydrophobicContact CB-CG2 4.1Å; N177-V180 WeakPolarHBondContact O-CG2 3.35Å; N177-V180 PolarHBondContact O-N 2.96Å
178	P	97.4	Very high	97.5	Very high	33 Å²	33	56.4 Å²	56.4	21%	0.214	30%	0.303	C	S	.	.	T	Hydrogen-bonded Turn	trans	-71.1	-15.9	179.4	31	-35.3	0	0	0	113.1	V180 V189 E190 Q193	P178-V180 PolarHBondContact O-N 3.15Å; P178-V189 HydrophobicContact CB-CG1 4.49Å; P178-E190 HydrophobicContact CB-CB 3.95Å; P178-E190 HydrophobicContact CB-CG 4.5Å; P178-E190 HydrophobicContact CG-CB 4.29Å; P178-E190 HydrophobicContact CG-CG 4.4Å; P178-Q193 VanDerWaalsContact CD-CD 3.44Å
179	D	96.5	Very high	97.5	Very high	136 Å²	136	54.6 Å²	54.6	73%	0.727	29%	0.288	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.6	-2.7	179.3	-60.3	-34	0	0	0	113.1	N177 P181	N177-D179 PolarHBondContact O-N 3.32Å; N177-D179 WeakPolarHBondContact OD1-CB 3.3Å; N177-D179 PolarHBondContact OD1-N 3.42Å; N177-D179 VanDerWaalsContact OD1-N 3.08Å; D179-P181 WeakPolarHBondContact O-CD 3.45Å
180	V	97.2	Very high	97.5	Very high	16 Å²	16	54 Å²	54	10%	0.097	29%	0.288	C	S	.	.	S	Bend	trans	-66.4	124.9	173.4	176.5	0	0	0	0	108.7	A92 L93 S96 N177 P178 L183	A92-V180 HydrophobicContact CB-CG1 3.84Å; L93-V180 HydrophobicContact CD2-CB 4.46Å; L93-V180 HydrophobicContact CD2-CG2 4.08Å; S96-V180 WeakPolarHBondContact OG-CG2 3.07Å; N177-V180 HydrophobicContact CB-CG2 4.1Å; N177-V180 WeakPolarHBondContact O-CG2 3.35Å; N177-V180 PolarHBondContact O-N 2.96Å; P178-V180 PolarHBondContact O-N 3.15Å; V180-L183 HydrophobicContact CB-CD1 3.95Å; V180-L183 HydrophobicContact CB-CD2 4.36Å; V180-L183 HydrophobicContact CB-CG 4.05Å; V180-L183 HydrophobicContact CG1-CD2 4.22Å; V180-L183 HydrophobicContact CG1-CG 4.25Å; V180-L183 WeakPolarHBondContact O-CG 3.43Å
181	P	94.6	Very high	97.5	Very high	101 Å²	101	55.8 Å²	55.8	66%	0.656	31%	0.306	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60	148.6	-178.9	-24.5	34	0	0	0	112.6	D179 L183	D179-P181 WeakPolarHBondContact O-CD 3.45Å; P181-L183 VanDerWaalsContact C-N 3.27Å; P181-L183 PolarHBondContact O-N 3.02Å
182	E	93.3	Very high	97.5	Very high	193 Å²	193	56.3 Å²	56.3	90%	0.902	31%	0.31	S	S	*	.	T	Hydrogen-bonded Turn	trans	64.8	20.7	168.1	-53.3	177.1	179	0	0	115.7	Q184	E182-Q184 PolarHBondContact O-N 3.39Å
183	L	97.8	Very high	97.5	Very high	24 Å²	24	57.6 Å²	57.6	13%	0.126	31%	0.314	C	S	.	.			trans	-63.8	126.3	171.7	-69.6	175.6	0	0	0	111.5	D89 A92 L93 V180 P181 V189	D89-L183 HydrophobicContact CB-CD2 3.83Å; A92-L183 HydrophobicContact CB-CD2 4.25Å; L93-L183 HydrophobicContact CD2-CD1 4.31Å; L93-L183 HydrophobicContact CD2-CD2 4.28Å; L93-L183 HydrophobicContact CG-CD2 4.13Å; V180-L183 HydrophobicContact CB-CD1 3.95Å; V180-L183 HydrophobicContact CB-CD2 4.36Å; V180-L183 HydrophobicContact CB-CG 4.05Å; V180-L183 HydrophobicContact CG1-CD2 4.22Å; V180-L183 HydrophobicContact CG1-CG 4.25Å; V180-L183 WeakPolarHBondContact O-CG 3.43Å; P181-L183 VanDerWaalsContact C-N 3.27Å; P181-L183 PolarHBondContact O-N 3.02Å; L183-V189 HydrophobicContact CD1-CB 4.34Å; L183-V189 HydrophobicContact CD1-CG1 4.24Å; L183-V189 HydrophobicContact CD1-CG2 4.24Å
184	Q	97.8	Very high	97.6	Very high	156 Å²	156	62.2 Å²	62.2	73%	0.729	33%	0.334	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.9	-37.8	175.2	-62.7	179.8	12.1	0	0	111.5	P86 D89 E182	P86-Q184 HydrophobicContact CG-CB 4.21Å; D89-Q184 PolarHBondContact OD1-N 3.16Å; D89-Q184 PolarHBondContact OD2-N 2.95Å; D89-Q184 VanDerWaalsContact OD2-N 3.16Å; E182-Q184 PolarHBondContact O-N 3.39Å
185	A	97.4	Very high	97.6	Very high	23 Å²	23	66.8 Å²	66.8	19%	0.19	35%	0.354	C	S	.	.	T	Hydrogen-bonded Turn	trans	-104.4	35.9	-179.3	0	0	0	0	0	112.4	L85 P86 D89 L187 F188 V189	L85-A185 HydrophobicContact CD2-CB 4Å; P86-A185 HydrophobicContact CG-CB 4.45Å; D89-A185 WeakPolarHBondContact OD2-CB 3.47Å; D89-A185 PolarHBondContact OD2-N 3Å; A185-L187 PolarHBondContact O-N 3.08Å; A185-F188 HydrophobicContact CB-CB 4.27Å; A185-F188 WeakPolarHBondContact O-CB 3.49Å; A185-F188 PolarHBondContact O-N 3.07Å; A185-V189 PolarHBondContact O-N 3.4Å
186	G	97.7	Very high	97.6	Very high	22 Å²	22	67.3 Å²	67.3	23%	0.227	36%	0.359	C	S	.	.	H	α-helix	trans	-51.7	-46	-174.8	0	0	0	0	0	114.6	F188 V189 E190	G186-F188 VanDerWaalsContact C-N 3.31Å; G186-F188 PolarHBondContact O-N 3.13Å; G186-V189 WeakPolarHBondContact O-CB 3.38Å; G186-V189 PolarHBondContact O-N 2.84Å; G186-E190 PolarHBondContact O-N 3.23Å
187	L	97.8	Very high	97.6	Very high	146 Å²	146	70 Å²	70	76%	0.764	37%	0.371	S	S	*	.	H	α-helix	trans	-63.7	-34.8	177.5	-67.1	176.4	0	0	0	113	A185 G191	A185-L187 PolarHBondContact O-N 3.08Å; L187-G191 PolarHBondContact O-N 3.25Å; L187-G191 VanDerWaalsContact O-N 3.09Å
188	F	98.2	Very high	97.6	Very high	89 Å²	89	73 Å²	73	39%	0.39	38%	0.384	S	S	.	.	H	α-helix	trans	-70.4	-40.9	176	179.2	-120.1	0	0	0	110.6	Q84 L85 A185 G186 E190 G191 L192	Q84-F188 HydrophobicContact CB-CE1 4.47Å; L85-F188 HydrophobicContact CD2-CD1 3.57Å; L85-F188 HydrophobicContact CD2-CE1 3.95Å; L85-F188 HydrophobicContact CG-CE1 4.48Å; A185-F188 HydrophobicContact CB-CB 4.27Å; A185-F188 WeakPolarHBondContact O-CB 3.49Å; A185-F188 PolarHBondContact O-N 3.07Å; G186-F188 VanDerWaalsContact C-N 3.31Å; G186-F188 PolarHBondContact O-N 3.13Å; F188-E190 VanDerWaalsContact C-N 3.33Å; F188-E190 PolarHBondContact O-N 2.86Å; F188-G191 PolarHBondContact O-N 3.19Å; F188-L192 HydrophobicContact CD1-CD1 4.02Å; F188-L192 HydrophobicContact CE1-CD1 3.66Å; F188-L192 HydrophobicContact CE1-CG 4.44Å; F188-L192 HydrophobicContact CE2-CD1 4.38Å; F188-L192 HydrophobicContact CE2-CD2 4.35Å; F188-L192 HydrophobicContact CE2-CG 4.31Å; F188-L192 HydrophobicContact CZ-CD1 3.86Å; F188-L192 HydrophobicContact CZ-CD2 4.26Å; F188-L192 HydrophobicContact CZ-CG 4.24Å; F188-L192 VanDerWaalsContact O-CG 3.31Å; F188-L192 WeakPolarHBondContact O-CG 3.4Å; F188-L192 PolarHBondContact O-N 2.85Å
189	V	98.6	Very high	97.7	Very high	0 Å²	0	72.1 Å²	72.1	0%	0	38%	0.379	C	S	.	.	H	α-helix	trans	-60.8	-42.1	173.5	175.5	0	0	0	0	111.3	L85 L93 F176 P178 L183 A185 G186 L192 Q193	L85-V189 HydrophobicContact CD1-CG2 4.42Å; L85-V189 HydrophobicContact CD2-CG2 3.79Å; L93-V189 HydrophobicContact CD1-CG2 4.23Å; L93-V189 HydrophobicContact CD2-CG1 4.28Å; F176-V189 HydrophobicContact CB-CG1 4.07Å; P178-V189 HydrophobicContact CB-CG1 4.49Å; L183-V189 HydrophobicContact CD1-CB 4.34Å; L183-V189 HydrophobicContact CD1-CG1 4.24Å; L183-V189 HydrophobicContact CD1-CG2 4.24Å; A185-V189 PolarHBondContact O-N 3.4Å; G186-V189 WeakPolarHBondContact O-CB 3.38Å; G186-V189 PolarHBondContact O-N 2.84Å; V189-L192 PolarHBondContact O-N 3.09Å; V189-Q193 PolarHBondContact O-N 3.25Å
190	E	98.5	Very high	97.7	Very high	78 Å²	78	65.6 Å²	65.6	36%	0.364	34%	0.344	S	S	.	.	H	α-helix	trans	-59.7	-47.7	175.4	-173.7	-178.8	-176.3	0	0	111.7	P178 G186 F188 L192 Q193 Q194	P178-E190 HydrophobicContact CB-CB 3.95Å; P178-E190 HydrophobicContact CB-CG 4.5Å; P178-E190 HydrophobicContact CG-CB 4.29Å; P178-E190 HydrophobicContact CG-CG 4.4Å; G186-E190 PolarHBondContact O-N 3.23Å; F188-E190 VanDerWaalsContact C-N 3.33Å; F188-E190 PolarHBondContact O-N 2.86Å; E190-L192 VanDerWaalsContact C-N 3.31Å; E190-L192 PolarHBondContact O-N 2.99Å; E190-Q193 WeakPolarHBondContact O-CB 3.47Å; E190-Q193 PolarHBondContact O-N 2.94Å; E190-Q193 VanDerWaalsContact O-N 3.1Å; E190-Q194 WeakPolarHBondContact O-CG 3.34Å; E190-Q194 PolarHBondContact O-N 3.28Å; E190-Q194 PolarHBondContact OE1-NE2 3.21Å
191	G	98.6	Very high	97.8	Very high	37 Å²	37	66 Å²	66	38%	0.381	35%	0.348	S	S	.	.	H	α-helix	trans	-58.9	-41.1	176	0	0	0	0	0	112.7	L187 F188 Q193 Q194 E195	L187-G191 PolarHBondContact O-N 3.25Å; L187-G191 VanDerWaalsContact O-N 3.09Å; F188-G191 PolarHBondContact O-N 3.19Å; G191-Q193 VanDerWaalsContact C-N 3.33Å; G191-Q193 PolarHBondContact O-N 3.44Å; G191-Q194 PolarHBondContact O-N 3.21Å; G191-E195 WeakPolarHBondContact O-CB 3.48Å; G191-E195 PolarHBondContact O-N 3.05Å
192	L	98.5	Very high	97.9	Very high	30 Å²	30	66.2 Å²	66.2	16%	0.157	34%	0.34	C	S	.	.	H	α-helix	trans	-66.3	-34.7	175.5	-66.8	173.3	0	0	0	112.7	A81 F176 F188 V189 E190 A196	A81-L192 HydrophobicContact CB-CD1 3.77Å; A81-L192 HydrophobicContact CB-CD2 3.57Å; A81-L192 HydrophobicContact CB-CG 4.34Å; F176-L192 HydrophobicContact CB-CB 3.97Å; F176-L192 HydrophobicContact CD1-CB 3.93Å; F176-L192 HydrophobicContact CD1-CD1 3.68Å; F176-L192 HydrophobicContact CD1-CG 4.48Å; F176-L192 HydrophobicContact CD2-CB 3.75Å; F176-L192 HydrophobicContact CE1-CB 4.39Å; F176-L192 HydrophobicContact CE1-CD1 3.59Å; F176-L192 HydrophobicContact CE2-CB 4.22Å; F176-L192 HydrophobicContact CG-CB 3.59Å; F176-L192 HydrophobicContact CG-CD1 4.24Å; F176-L192 HydrophobicContact CZ-CD1 4.05Å; F188-L192 HydrophobicContact CD1-CD1 4.02Å; F188-L192 HydrophobicContact CE1-CD1 3.66Å; F188-L192 HydrophobicContact CE1-CG 4.44Å; F188-L192 HydrophobicContact CE2-CD1 4.38Å; F188-L192 HydrophobicContact CE2-CD2 4.35Å; F188-L192 HydrophobicContact CE2-CG 4.31Å; F188-L192 HydrophobicContact CZ-CD1 3.86Å; F188-L192 HydrophobicContact CZ-CD2 4.26Å; F188-L192 HydrophobicContact CZ-CG 4.24Å; F188-L192 VanDerWaalsContact O-CG 3.31Å; F188-L192 WeakPolarHBondContact O-CG 3.4Å; F188-L192 PolarHBondContact O-N 2.85Å; V189-L192 PolarHBondContact O-N 3.09Å; E190-L192 VanDerWaalsContact C-N 3.31Å; E190-L192 PolarHBondContact O-N 2.99Å; L192-A196 WeakPolarHBondContact O-CB 3.38Å; L192-A196 PolarHBondContact O-N 2.65Å
193	Q	98.6	Very high	98.1	Very high	35 Å²	35	57.5 Å²	57.5	16%	0.164	30%	0.3	C	S	.	.	H	α-helix	trans	-65.7	-47.2	174.7	-164.1	-180	54.4	0	0	111.4	T173 F176 P178 V189 E190 G191 E195 A196 Q197	T173-Q193 PolarHBondContact O-NE2 3.28Å; F176-Q193 HydrophobicContact CB-CB 4.22Å; F176-Q193 WeakPolarHBondContact O-CB 3.32Å; F176-Q193 WeakPolarHBondContact O-CG 3.47Å; F176-Q193 PolarHBondContact O-NE2 3.24Å; P178-Q193 VanDerWaalsContact CD-CD 3.44Å; V189-Q193 PolarHBondContact O-N 3.25Å; E190-Q193 WeakPolarHBondContact O-CB 3.47Å; E190-Q193 PolarHBondContact O-N 2.94Å; E190-Q193 VanDerWaalsContact O-N 3.1Å; G191-Q193 VanDerWaalsContact C-N 3.33Å; G191-Q193 PolarHBondContact O-N 3.44Å; Q193-E195 VanDerWaalsContact C-N 3.32Å; Q193-E195 PolarHBondContact O-N 3.45Å; Q193-A196 PolarHBondContact O-N 3.17Å; Q193-Q197 WeakPolarHBondContact O-CG 3.47Å; Q193-Q197 PolarHBondContact O-N 2.72Å
194	Q	98.5	Very high	98	Very high	110 Å²	110	56.5 Å²	56.5	51%	0.514	30%	0.295	S	S	.	.	H	α-helix	trans	-60.1	-44.1	178.5	-69.9	175.7	5.4	0	0	110.9	E190 G191 A196 Q197 H198	E190-Q194 WeakPolarHBondContact O-CG 3.34Å; E190-Q194 PolarHBondContact O-N 3.28Å; E190-Q194 PolarHBondContact OE1-NE2 3.21Å; G191-Q194 PolarHBondContact O-N 3.21Å; Q194-A196 PolarHBondContact O-N 3.28Å; Q194-Q197 PolarHBondContact O-N 2.68Å; Q194-H198 WeakPolarHBondContact O-CB 3.49Å; Q194-H198 PolarHBondContact O-N 2.85Å
195	E	98.4	Very high	97.9	Very high	123 Å²	123	55 Å²	55	58%	0.575	29%	0.288	S	S	*	.	H	α-helix	trans	-60.5	-46.1	175.8	-172.1	63.4	-152.7	0	0	111.7	G191 Q193 Q197 H198 A199	G191-E195 WeakPolarHBondContact O-CB 3.48Å; G191-E195 PolarHBondContact O-N 3.05Å; Q193-E195 VanDerWaalsContact C-N 3.32Å; Q193-E195 PolarHBondContact O-N 3.45Å; E195-Q197 VanDerWaalsContact C-N 3.34Å; E195-Q197 PolarHBondContact O-N 3.09Å; E195-H198 PolarHBondContact O-N 3.37Å; E195-A199 WeakPolarHBondContact O-CB 3.35Å; E195-A199 PolarHBondContact O-N 3.09Å
196	A	98.3	Very high	97.8	Very high	11 Å²	11	60.3 Å²	60.3	9%	0.091	31%	0.312	C	S	.	.	H	α-helix	trans	-64.4	-38	177.9	0	0	0	0	0	112.5	T173 L192 Q193 Q194 L200	T173-A196 HydrophobicContact CG2-CB 3.79Å; L192-A196 WeakPolarHBondContact O-CB 3.38Å; L192-A196 PolarHBondContact O-N 2.65Å; Q193-A196 PolarHBondContact O-N 3.17Å; Q194-A196 PolarHBondContact O-N 3.28Å; A196-L200 WeakPolarHBondContact O-CB 3.45Å; A196-L200 PolarHBondContact O-N 2.9Å
197	Q	98.1	Very high	97.7	Very high	68 Å²	68	63 Å²	63	32%	0.318	32%	0.321	S	S	.	.	H	α-helix	trans	-68.8	-41.2	175.9	-75	-178.9	-1.5	0	0	111.6	T173 Q193 Q194 E195 L200 S201 F215	T173-Q197 HydrophobicContact CG2-CB 4.22Å; T173-Q197 HydrophobicContact CG2-CG 3.47Å; T173-Q197 VanDerWaalsContact CG2-CG 3.47Å; Q193-Q197 WeakPolarHBondContact O-CG 3.47Å; Q193-Q197 PolarHBondContact O-N 2.72Å; Q194-Q197 PolarHBondContact O-N 2.68Å; E195-Q197 VanDerWaalsContact C-N 3.34Å; E195-Q197 PolarHBondContact O-N 3.09Å; Q197-L200 PolarHBondContact O-N 3.31Å; Q197-S201 PolarHBondContact O-N 3.47Å; Q197-F215 WeakPolarHBondContact O-CE2 3.49Å
198	H	98.2	Very high	97.5	Very high	103 Å²	103	58.6 Å²	58.6	48%	0.477	30%	0.296	S	S	.	.	H	α-helix	trans	-61.8	-51.1	176.6	-171.7	67.9	0	0	0	110.6	Q194 E195 L200 S201 E202	Q194-H198 WeakPolarHBondContact O-CB 3.49Å; Q194-H198 PolarHBondContact O-N 2.85Å; E195-H198 PolarHBondContact O-N 3.37Å; H198-L200 VanDerWaalsContact C-N 3.28Å; H198-L200 PolarHBondContact O-N 2.89Å; H198-S201 WeakPolarHBondContact O-CA 3.36Å; H198-S201 WeakPolarHBondContact O-CB 3.35Å; H198-S201 PolarHBondContact O-N 3.26Å; H198-E202 IonicContact CD2-OE2 3.63Å; H198-E202 IonicContact NE2-OE1 3.93Å; H198-E202 IonicContact NE2-OE2 2.66Å; H198-E202 WeakPolarHBondContact O-CG 3.4Å; H198-E202 PolarHBondContact O-N 2.95Å
199	A	98.3	Very high	97	Very high	13 Å²	13	59.4 Å²	59.4	11%	0.107	31%	0.311	C	S	.	.	H	α-helix	trans	-61.5	-34.7	177.7	0	0	0	0	0	112.8	Y169 E195 V203	Y169-A199 HydrophobicContact CD1-CB 3.51Å; Y169-A199 HydrophobicContact CD2-CB 4.43Å; Y169-A199 HydrophobicContact CE1-CB 3.39Å; Y169-A199 HydrophobicContact CE2-CB 4.34Å; Y169-A199 HydrophobicContact CG-CB 4.06Å; E195-A199 WeakPolarHBondContact O-CB 3.35Å; E195-A199 PolarHBondContact O-N 3.09Å; A199-V203 WeakPolarHBondContact O-CB 3.23Å; A199-V203 PolarHBondContact O-N 3.4Å
200	L	98.3	Very high	96.5	Very high	0 Å²	0	62.6 Å²	62.6	0%	0	34%	0.344	C	S	.	.	H	α-helix	trans	-64.1	-44.2	171.3	-179.9	59.8	0	0	0	111.6	E166 L170 A196 Q197 H198 V203 V204 F215 I218 L219	E166-L200 HydrophobicContact CB-CD1 4.11Å; E166-L200 HydrophobicContact CG-CD1 4.22Å; L170-L200 HydrophobicContact CB-CD2 4.43Å; L170-L200 HydrophobicContact CD1-CD2 4.35Å; A196-L200 WeakPolarHBondContact O-CB 3.45Å; A196-L200 PolarHBondContact O-N 2.9Å; Q197-L200 PolarHBondContact O-N 3.31Å; H198-L200 VanDerWaalsContact C-N 3.28Å; H198-L200 PolarHBondContact O-N 2.89Å; L200-V203 HydrophobicContact CD1-CG1 4.31Å; L200-V203 WeakPolarHBondContact O-CG1 3.46Å; L200-V204 HydrophobicContact CD1-CG2 4.22Å; L200-V204 WeakPolarHBondContact O-CB 3.47Å; L200-V204 WeakPolarHBondContact O-CG2 3.19Å; L200-V204 PolarHBondContact O-N 3.22Å; L200-F215 HydrophobicContact CB-CE2 4.09Å; L200-F215 HydrophobicContact CD2-CD2 4.3Å; L200-F215 HydrophobicContact CD2-CE2 3.99Å; L200-F215 HydrophobicContact CG-CD2 4.01Å; L200-F215 HydrophobicContact CG-CE2 3.91Å; L200-I218 HydrophobicContact CD2-CG2 4.11Å; L200-L219 HydrophobicContact CD2-CD2 4.3Å
201	S	97.5	Very high	96	Very high	25 Å²	25	63.3 Å²	63.3	18%	0.175	35%	0.347	C	S	.	.	H	α-helix	trans	-62.2	-46.5	177.1	-175.1	0	0	0	0	111.5	Q197 H198 V204 Q205	Q197-S201 PolarHBondContact O-N 3.47Å; H198-S201 WeakPolarHBondContact O-CA 3.36Å; H198-S201 WeakPolarHBondContact O-CB 3.35Å; H198-S201 PolarHBondContact O-N 3.26Å; S201-V204 PolarHBondContact O-N 3.06Å; S201-Q205 VanDerWaalsContact O-CG 3.31Å; S201-Q205 WeakPolarHBondContact O-CG 3.28Å; S201-Q205 PolarHBondContact O-N 2.94Å; S201-Q205 PolarHBondContact OG-NE2 2.87Å
202	E	97.3	Very high	95.3	Very high	104 Å²	104	70.5 Å²	70.5	49%	0.486	37%	0.371	S	S	.	.	H	α-helix	trans	-62.1	-45.4	178	-70.1	-169.7	119.8	0	0	112.1	H198 V204 Q205 L206	H198-E202 IonicContact CD2-OE2 3.63Å; H198-E202 IonicContact NE2-OE1 3.93Å; H198-E202 IonicContact NE2-OE2 2.66Å; H198-E202 WeakPolarHBondContact O-CG 3.4Å; H198-E202 PolarHBondContact O-N 2.95Å; E202-V204 VanDerWaalsContact C-N 3.3Å; E202-V204 PolarHBondContact O-N 2.92Å; E202-Q205 PolarHBondContact O-N 3.3Å; E202-L206 WeakPolarHBondContact O-CB 3.46Å; E202-L206 PolarHBondContact O-N 3.31Å
203	V	97.3	Very high	95.1	Very high	10 Å²	10	73.6 Å²	73.6	6%	0.061	38%	0.384	C	S	.	.	H	α-helix	trans	-66.3	-36.1	179.8	84.4	0	0	0	0	111.7	K165 E166 Y169 A199 L200 L206 L207	K165-V203 HydrophobicContact CB-CG2 3.98Å; K165-V203 HydrophobicContact CD-CG2 4.04Å; E166-V203 HydrophobicContact CG-CG1 3.8Å; Y169-V203 HydrophobicContact CD2-CB 4.26Å; Y169-V203 HydrophobicContact CD2-CG1 3.8Å; Y169-V203 HydrophobicContact CE2-CB 4.03Å; Y169-V203 HydrophobicContact CE2-CG1 4.08Å; Y169-V203 HydrophobicContact CE2-CG2 4.35Å; A199-V203 WeakPolarHBondContact O-CB 3.23Å; A199-V203 PolarHBondContact O-N 3.4Å; L200-V203 HydrophobicContact CD1-CG1 4.31Å; L200-V203 WeakPolarHBondContact O-CG1 3.46Å; V203-L206 PolarHBondContact O-N 3.33Å; V203-L207 HydrophobicContact CG2-CD1 3.83Å; V203-L207 HydrophobicContact CG2-CG 4.15Å; V203-L207 WeakPolarHBondContact O-CB 3.37Å; V203-L207 VanDerWaalsContact O-CG 3.29Å; V203-L207 WeakPolarHBondContact O-CG 3.14Å; V203-L207 PolarHBondContact O-N 3.31Å
204	V	96.8	Very high	95	Very high	4 Å²	4	72.5 Å²	72.5	2%	0.024	38%	0.379	C	S	.	.	H	α-helix	trans	-63.7	-46.3	174.9	166.4	0	0	0	0	110.4	E166 L200 S201 E202 L206 L207 H208 R214 F215 I218	E166-V204 HydrophobicContact CG-CG2 4.23Å; E166-V204 WeakPolarHBondContact OE1-CG2 3.48Å; L200-V204 HydrophobicContact CD1-CG2 4.22Å; L200-V204 WeakPolarHBondContact O-CB 3.47Å; L200-V204 WeakPolarHBondContact O-CG2 3.19Å; L200-V204 PolarHBondContact O-N 3.22Å; S201-V204 PolarHBondContact O-N 3.06Å; E202-V204 VanDerWaalsContact C-N 3.3Å; E202-V204 PolarHBondContact O-N 2.92Å; V204-L206 VanDerWaalsContact C-N 3.31Å; V204-L206 PolarHBondContact O-N 3.4Å; V204-L207 PolarHBondContact O-N 3.25Å; V204-H208 CarbonylContact O-C 3.57Å; V204-H208 WeakPolarHBondContact O-CA 3.38Å; V204-H208 WeakPolarHBondContact O-CB 3.39Å; V204-H208 PolarHBondContact O-N 3.48Å; V204-R214 HydrophobicContact CG1-CB 3.81Å; V204-R214 HydrophobicContact CG1-CG 3.93Å; V204-F215 HydrophobicContact CG1-CB 4.21Å; V204-I218 HydrophobicContact CG2-CD1 3.71Å
205	Q	95.7	Very high	94.9	Very high	124 Å²	124	69.7 Å²	69.7	58%	0.579	37%	0.365	S	S	*	.	H	α-helix	trans	-62.3	-39.3	177.7	-71.2	174.9	33.8	0	0	111.9	S201 E202 P209	S201-Q205 VanDerWaalsContact O-CG 3.31Å; S201-Q205 WeakPolarHBondContact O-CG 3.28Å; S201-Q205 PolarHBondContact O-N 2.94Å; S201-Q205 PolarHBondContact OG-NE2 2.87Å; E202-Q205 PolarHBondContact O-N 3.3Å; Q205-P209 VanDerWaalsContact O-CA 3.32Å; Q205-P209 WeakPolarHBondContact O-CA 3.37Å
206	L	95.7	Very high	94.8	Very high	134 Å²	134	66.1 Å²	66.1	70%	0.702	36%	0.356	S	S	*	.	H	α-helix	trans	-69.2	-45.5	179.5	-177.9	67.3	0	0	0	112.6	E202 V203 V204	E202-L206 WeakPolarHBondContact O-CB 3.46Å; E202-L206 PolarHBondContact O-N 3.31Å; V203-L206 PolarHBondContact O-N 3.33Å; V204-L206 VanDerWaalsContact C-N 3.31Å; V204-L206 PolarHBondContact O-N 3.4Å
207	L	94.4	Very high	94.8	Very high	79 Å²	79	70.2 Å²	70.2	41%	0.414	37%	0.37	S	S	.	.	H	α-helix	trans	-81.8	-26.7	-176.8	-63.8	179.5	0	0	0	112.6	V203 V204	V203-L207 HydrophobicContact CG2-CD1 3.83Å; V203-L207 HydrophobicContact CG2-CG 4.15Å; V203-L207 WeakPolarHBondContact O-CB 3.37Å; V203-L207 VanDerWaalsContact O-CG 3.29Å; V203-L207 WeakPolarHBondContact O-CG 3.14Å; V203-L207 PolarHBondContact O-N 3.31Å; V204-L207 PolarHBondContact O-N 3.25Å
208	H	93.2	Very high	94.8	Very high	53 Å²	53	67 Å²	67	25%	0.245	35%	0.354	C	S	.	.			trans	-137.2	60.8	-173.1	-54.9	-74.3	0	0	0	112.6	E166 V204 G210 H211 R214	E166-H208 IonicContact OE1-CD2 3.84Å; E166-H208 IonicContact OE1-NE2 3.7Å; V204-H208 CarbonylContact O-C 3.57Å; V204-H208 WeakPolarHBondContact O-CA 3.38Å; V204-H208 WeakPolarHBondContact O-CB 3.39Å; V204-H208 PolarHBondContact O-N 3.48Å; H208-G210 PolarHBondContact O-N 3.27Å; H208-H211 HydrophobicContact CB-CB 4.19Å; H208-H211 PolarHBondContact O-N 3.24Å; H208-R214 WeakPolarHBondContact CD2-CD 3.47Å; H208-R214 PolarHBondContact CD2-NE 2.48Å; H208-R214 PolarHBondContact NE2-NE 3.38Å
209	P	88.4	Confident	94.7	Very high	107 Å²	107	64.7 Å²	64.7	70%	0.695	35%	0.345	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61	-19.5	-172.7	23.1	-34.5	0	0	0	115	Q205	Q205-P209 VanDerWaalsContact O-CA 3.32Å; Q205-P209 WeakPolarHBondContact O-CA 3.37Å
210	G	87.3	Confident	94.7	Very high	67 Å²	67	69.9 Å²	69.9	69%	0.691	37%	0.37	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.7	-4.5	176.8	0	0	0	0	0	115.7	H208	H208-G210 PolarHBondContact O-N 3.27Å
211	H	88.1	Confident	94.6	Very high	93 Å²	93	70.5 Å²	70.5	43%	0.431	37%	0.374	S	S	.	.			trans	-115.4	70.7	-173	-65.6	-80.9	0	0	0	111.6	H208 E213 R214	H208-H211 HydrophobicContact CB-CB 4.19Å; H208-H211 PolarHBondContact O-N 3.24Å; H211-E213 IonicContact ND1-OE1 3.73Å; H211-E213 PolarHBondContact O-N 3.1Å; H211-E213 VanDerWaalsContact O-N 3.12Å; H211-R214 HydrophobicContact CB-CB 3.94Å; H211-R214 VanDerWaalsContact O-CB 3.32Å; H211-R214 WeakPolarHBondContact O-CB 3.26Å; H211-R214 PolarHBondContact O-N 3.45Å
212	Q	85.5	Confident	94.6	Very high	188 Å²	188	70 Å²	70	88%	0.879	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.9	-26.3	-177.1	-64.8	-176	-15.9	0	0	112.9
213	E	94	Very high	94.6	Very high	94 Å²	94	68 Å²	68	44%	0.439	37%	0.369	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84	-11.2	179.3	81.8	-68.4	172.1	0	0	114.1	H211 F215 A216 R217	H211-E213 IonicContact ND1-OE1 3.73Å; H211-E213 PolarHBondContact O-N 3.1Å; H211-E213 VanDerWaalsContact O-N 3.12Å; E213-F215 PolarHBondContact O-N 3.2Å; E213-A216 PolarHBondContact O-N 3Å; E213-R217 WeakPolarHBondContact O-CB 3.47Å; E213-R217 PolarHBondContact O-N 3.08Å; E213-R217 IonicContact OE1-NH1 3.37Å; E213-R217 PolarHBondContact OE1-NH1 3.09Å
214	R	95.8	Very high	94.6	Very high	13 Å²	13	70.7 Å²	70.7	5%	0.049	38%	0.382	C	S	.	.	H	α-helix	trans	-60.6	-44.3	-172.9	179.6	174.5	177	91.4	-3	112	L160 D161 E166 V204 H208 H211 A216 R217 I218	L160-R214 VanDerWaalsContact O-CZ 3.32Å; L160-R214 PolarHBondContact O-NH1 3.4Å; L160-R214 PolarHBondContact O-NH2 2.89Å; D161-R214 PolarHBondContact O-NH2 3.43Å; E166-R214 IonicContact OE1-CZ 2.76Å; E166-R214 IonicContact OE1-NE 3.95Å; E166-R214 PolarHBondContact OE1-NE 2.86Å; E166-R214 IonicContact OE1-NH2 3.76Å; E166-R214 PolarHBondContact OE1-NH2 2.97Å; E166-R214 VanDerWaalsContact OE1-NH2 3.13Å; E166-R214 IonicContact OE2-CZ 3.63Å; E166-R214 IonicContact OE2-NH2 2.75Å; E166-R214 PolarHBondContact OE2-NH2 3.16Å; V204-R214 HydrophobicContact CG1-CB 3.81Å; V204-R214 HydrophobicContact CG1-CG 3.93Å; H208-R214 WeakPolarHBondContact CD2-CD 3.47Å; H208-R214 PolarHBondContact CD2-NE 2.48Å; H208-R214 PolarHBondContact NE2-NE 3.38Å; H211-R214 HydrophobicContact CB-CB 3.94Å; H211-R214 VanDerWaalsContact O-CB 3.32Å; H211-R214 WeakPolarHBondContact O-CB 3.26Å; H211-R214 PolarHBondContact O-N 3.45Å; R214-A216 PolarHBondContact O-N 2.69Å; R214-R217 WeakPolarHBondContact O-CB 3.45Å; R214-R217 PolarHBondContact O-N 3.21Å; R214-R217 VanDerWaalsContact O-N 3.16Å; R214-I218 HydrophobicContact CG-CD1 3.99Å; R214-I218 HydrophobicContact CG-CG1 4.39Å; R214-I218 VanDerWaalsContact O-CG1 3.29Å; R214-I218 WeakPolarHBondContact O-CG1 3.34Å; R214-I218 PolarHBondContact O-N 2.77Å
215	F	96.7	Very high	94.6	Very high	50 Å²	50	70.8 Å²	70.8	22%	0.219	38%	0.383	C	S	.	.	H	α-helix	trans	-57.5	-50.6	177.9	176.1	-107	0	0	0	111.4	Q197 L200 V204 E213 R217 I218 L219	Q197-F215 WeakPolarHBondContact O-CE2 3.49Å; L200-F215 HydrophobicContact CB-CE2 4.09Å; L200-F215 HydrophobicContact CD2-CD2 4.3Å; L200-F215 HydrophobicContact CD2-CE2 3.99Å; L200-F215 HydrophobicContact CG-CD2 4.01Å; L200-F215 HydrophobicContact CG-CE2 3.91Å; V204-F215 HydrophobicContact CG1-CB 4.21Å; E213-F215 PolarHBondContact O-N 3.2Å; F215-R217 VanDerWaalsContact C-N 3.31Å; F215-R217 PolarHBondContact O-N 3.18Å; F215-I218 WeakPolarHBondContact O-CB 3.22Å; F215-I218 PolarHBondContact O-N 3.32Å; F215-L219 HydrophobicContact CD1-CD1 4.23Å; F215-L219 HydrophobicContact CE1-CD1 3.56Å; F215-L219 HydrophobicContact CE1-CG 4.42Å; F215-L219 HydrophobicContact CE2-CD1 4.24Å; F215-L219 HydrophobicContact CE2-CG 4.42Å; F215-L219 HydrophobicContact CZ-CD1 3.58Å; F215-L219 HydrophobicContact CZ-CG 4.24Å; F215-L219 PolarHBondContact O-N 2.82Å; F215-L219 VanDerWaalsContact O-N 3.1Å
216	A	96.7	Very high	94.5	Very high	49 Å²	49	73.2 Å²	73.2	41%	0.405	39%	0.394	S	S	.	.	H	α-helix	trans	-60.3	-40.9	176.4	0	0	0	0	0	111.8	E213 R214 I218 L219 L220	E213-A216 PolarHBondContact O-N 3Å; R214-A216 PolarHBondContact O-N 2.69Å; A216-I218 VanDerWaalsContact C-N 3.33Å; A216-I218 PolarHBondContact O-N 3.19Å; A216-L219 PolarHBondContact O-N 3.37Å; A216-L220 WeakPolarHBondContact O-CB 3.16Å; A216-L220 VanDerWaalsContact O-CG 3.26Å; A216-L220 WeakPolarHBondContact O-CG 3.44Å; A216-L220 PolarHBondContact O-N 3.23Å
217	R	97.1	Very high	94.4	Very high	97 Å²	97	69.1 Å²	69.1	37%	0.366	38%	0.384	S	S	.	.	H	α-helix	trans	-64.3	-36.4	178	-163.9	171.8	65.8	-150.6	3.4	112.6	L160 E213 R214 F215 T221	L160-R217 HydrophobicContact CD2-CG 3.89Å; E213-R217 WeakPolarHBondContact O-CB 3.47Å; E213-R217 PolarHBondContact O-N 3.08Å; E213-R217 IonicContact OE1-NH1 3.37Å; E213-R217 PolarHBondContact OE1-NH1 3.09Å; R214-R217 WeakPolarHBondContact O-CB 3.45Å; R214-R217 PolarHBondContact O-N 3.21Å; R214-R217 VanDerWaalsContact O-N 3.16Å; F215-R217 VanDerWaalsContact C-N 3.31Å; F215-R217 PolarHBondContact O-N 3.18Å; R217-T221 WeakPolarHBondContact O-CB 3.4Å; R217-T221 PolarHBondContact O-N 2.64Å; R217-T221 PolarHBondContact O-OG1 3.36Å
218	I	98.2	Very high	94.5	Very high	0 Å²	0	66 Å²	66	0%	0	37%	0.367	C	S	.	.	H	α-helix	trans	-62.6	-51.5	173.2	-68.2	169.2	0	0	0	109.9	L160 L162 L170 L200 V204 R214 F215 A216 L220 T221 A222	L160-I218 HydrophobicContact CD1-CG1 4.3Å; L162-I218 HydrophobicContact CD2-CD1 3.73Å; L162-I218 HydrophobicContact CD2-CG1 3.76Å; L170-I218 HydrophobicContact CD1-CG2 4.04Å; L170-I218 HydrophobicContact CD2-CG2 4.01Å; L200-I218 HydrophobicContact CD2-CG2 4.11Å; V204-I218 HydrophobicContact CG2-CD1 3.71Å; R214-I218 HydrophobicContact CG-CD1 3.99Å; R214-I218 HydrophobicContact CG-CG1 4.39Å; R214-I218 VanDerWaalsContact O-CG1 3.29Å; R214-I218 WeakPolarHBondContact O-CG1 3.34Å; R214-I218 PolarHBondContact O-N 2.77Å; F215-I218 WeakPolarHBondContact O-CB 3.22Å; F215-I218 PolarHBondContact O-N 3.32Å; A216-I218 VanDerWaalsContact C-N 3.33Å; A216-I218 PolarHBondContact O-N 3.19Å; I218-L220 PolarHBondContact O-N 3.04Å; I218-T221 PolarHBondContact O-N 3.14Å; I218-T221 VanDerWaalsContact O-N 3.14Å; I218-A222 WeakPolarHBondContact O-CB 3.23Å; I218-A222 PolarHBondContact O-N 2.96Å
219	L	97	Very high	94.6	Very high	55 Å²	55	65.9 Å²	65.9	29%	0.288	37%	0.371	S	S	.	.	H	α-helix	trans	-63.2	-40.5	-179.9	-63.5	-175.5	0	0	0	112.6	L200 F215 A216 T221 A222 S223	L200-L219 HydrophobicContact CD2-CD2 4.3Å; F215-L219 HydrophobicContact CD1-CD1 4.23Å; F215-L219 HydrophobicContact CE1-CD1 3.56Å; F215-L219 HydrophobicContact CE1-CG 4.42Å; F215-L219 HydrophobicContact CE2-CD1 4.24Å; F215-L219 HydrophobicContact CE2-CG 4.42Å; F215-L219 HydrophobicContact CZ-CD1 3.58Å; F215-L219 HydrophobicContact CZ-CG 4.24Å; F215-L219 PolarHBondContact O-N 2.82Å; F215-L219 VanDerWaalsContact O-N 3.1Å; A216-L219 PolarHBondContact O-N 3.37Å; L219-T221 VanDerWaalsContact C-N 3.29Å; L219-T221 PolarHBondContact O-N 2.74Å; L219-A222 WeakPolarHBondContact O-CB 3.25Å; L219-A222 PolarHBondContact O-N 2.83Å; L219-S223 PolarHBondContact O-N 3.06Å
220	L	97	Very high	95	Very high	121 Å²	121	63.7 Å²	63.7	63%	0.634	36%	0.356	S	S	*	.	H	α-helix	trans	-64.7	-33.2	174.6	-73	171.9	0	0	0	112.5	A216 I218 S223	A216-L220 WeakPolarHBondContact O-CB 3.16Å; A216-L220 VanDerWaalsContact O-CG 3.26Å; A216-L220 WeakPolarHBondContact O-CG 3.44Å; A216-L220 PolarHBondContact O-N 3.23Å; I218-L220 PolarHBondContact O-N 3.04Å; L220-S223 PolarHBondContact O-OG 2.81Å
221	T	97.9	Very high	95.3	Very high	13 Å²	13	62.6 Å²	62.6	8%	0.08	34%	0.338	C	S	.	.	H	α-helix	trans	-74.3	-36.5	174.3	-55.2	0	0	0	0	110.8	K156 F157 L160 R217 I218 L219 S223 M224	K156-T221 HydrophobicContact CB-CG2 3.78Å; F157-T221 HydrophobicContact CD1-CG2 4.06Å; F157-T221 HydrophobicContact CD2-CG2 4.08Å; F157-T221 HydrophobicContact CE1-CG2 3.94Å; F157-T221 HydrophobicContact CE2-CG2 3.98Å; F157-T221 HydrophobicContact CG-CG2 4.12Å; F157-T221 HydrophobicContact CZ-CG2 3.91Å; L160-T221 HydrophobicContact CD1-CG2 3.9Å; R217-T221 WeakPolarHBondContact O-CB 3.4Å; R217-T221 PolarHBondContact O-N 2.64Å; R217-T221 PolarHBondContact O-OG1 3.36Å; I218-T221 PolarHBondContact O-N 3.14Å; I218-T221 VanDerWaalsContact O-N 3.14Å; L219-T221 VanDerWaalsContact C-N 3.29Å; L219-T221 PolarHBondContact O-N 2.74Å; T221-S223 VanDerWaalsContact C-N 3.3Å; T221-S223 PolarHBondContact O-N 2.63Å; T221-M224 HydrophobicContact CG2-SD 4.36Å; T221-M224 VanDerWaalsContact O-CB 3.23Å; T221-M224 WeakPolarHBondContact O-CB 3.38Å; T221-M224 WeakPolarHBondContact O-CG 3.35Å; T221-M224 PolarHBondContact O-N 3.25Å; T221-M224 VanDerWaalsContact O-N 3.13Å
222	A	97.2	Very high	95.7	Very high	16 Å²	16	58.4 Å²	58.4	13%	0.132	32%	0.319	C	S	.	.	H	α-helix	trans	-62.9	-33.2	175.7	0	0	0	0	0	113	L170 I218 L219 M224 L225	L170-A222 HydrophobicContact CD1-CB 3.87Å; I218-A222 WeakPolarHBondContact O-CB 3.23Å; I218-A222 PolarHBondContact O-N 2.96Å; L219-A222 WeakPolarHBondContact O-CB 3.25Å; L219-A222 PolarHBondContact O-N 2.83Å; A222-M224 PolarHBondContact O-N 2.95Å; A222-L225 HydrophobicContact CB-CD1 4.42Å; A222-L225 WeakPolarHBondContact O-CB 3.27Å; A222-L225 WeakPolarHBondContact O-CD1 3.25Å; A222-L225 WeakPolarHBondContact O-CG 3.33Å; A222-L225 PolarHBondContact O-N 2.76Å
223	S	96.4	Very high	96.3	Very high	61 Å²	61	49.4 Å²	49.4	43%	0.427	28%	0.277	S	S	.	.	G	3₁₀ helix	trans	-62	-24.5	175.1	75.9	0	0	0	0	113.1	L219 L220 T221 L225 Q226	L219-S223 PolarHBondContact O-N 3.06Å; L220-S223 PolarHBondContact O-OG 2.81Å; T221-S223 VanDerWaalsContact C-N 3.3Å; T221-S223 PolarHBondContact O-N 2.63Å; S223-L225 PolarHBondContact O-N 3.17Å; S223-Q226 WeakPolarHBondContact O-CB 3.33Å; S223-Q226 PolarHBondContact O-N 3.15Å
224	M	96.8	Very high	96.4	Very high	66 Å²	66	46 Å²	46	33%	0.325	27%	0.265	S	S	.	.	G	3₁₀ helix	trans	-62.7	-24.7	175.2	-58.5	-179.2	62.8	0	0	112.9	C153 K156 T221 A222 Q226 G227	C153-M224 HydrophobicContact CB-CE 4.37Å; K156-M224 HydrophobicContact CB-SD 4.21Å; K156-M224 HydrophobicContact CG-CE 4.13Å; K156-M224 HydrophobicContact CG-SD 3.96Å; T221-M224 HydrophobicContact CG2-SD 4.36Å; T221-M224 VanDerWaalsContact O-CB 3.23Å; T221-M224 WeakPolarHBondContact O-CB 3.38Å; T221-M224 WeakPolarHBondContact O-CG 3.35Å; T221-M224 PolarHBondContact O-N 3.25Å; T221-M224 VanDerWaalsContact O-N 3.13Å; A222-M224 PolarHBondContact O-N 2.95Å; M224-Q226 PolarHBondContact O-N 3.38Å; M224-G227 PolarHBondContact O-N 3.2Å; M224-G227 VanDerWaalsContact O-N 3.09Å
225	L	96.8	Very high	96.4	Very high	7 Å²	7	47.5 Å²	47.5	4%	0.037	27%	0.272	C	S	.	.	G	3₁₀ helix	trans	-59.3	-33	178.2	-62.2	169.9	0	0	0	111.6	P100 I103 L104 F157 A222 S223 G227 I228	P100-L225 HydrophobicContact CB-CB 4.19Å; P100-L225 HydrophobicContact CB-CD1 4.16Å; I103-L225 HydrophobicContact CB-CD2 3.72Å; I103-L225 HydrophobicContact CD1-CD2 3.95Å; I103-L225 HydrophobicContact CG1-CD2 4.49Å; I103-L225 HydrophobicContact CG2-CD2 3.53Å; L104-L225 HydrophobicContact CD1-CD1 4.2Å; L104-L225 HydrophobicContact CD2-CD1 4.08Å; L104-L225 HydrophobicContact CG-CD1 3.97Å; F157-L225 HydrophobicContact CE2-CD2 3.78Å; F157-L225 HydrophobicContact CE2-CG 4.14Å; F157-L225 HydrophobicContact CZ-CD1 4.21Å; F157-L225 HydrophobicContact CZ-CD2 4.26Å; F157-L225 HydrophobicContact CZ-CG 4.24Å; A222-L225 HydrophobicContact CB-CD1 4.42Å; A222-L225 WeakPolarHBondContact O-CB 3.27Å; A222-L225 WeakPolarHBondContact O-CD1 3.25Å; A222-L225 WeakPolarHBondContact O-CG 3.33Å; A222-L225 PolarHBondContact O-N 2.76Å; S223-L225 PolarHBondContact O-N 3.17Å; L225-G227 PolarHBondContact O-N 3.16Å; L225-I228 PolarHBondContact O-N 3.42Å
226	Q	93.3	Very high	96.3	Very high	175 Å²	175	45.3 Å²	45.3	82%	0.818	26%	0.263	S	S	*	.	G	3₁₀ helix	trans	-66.9	-19.8	179.6	-59.7	179.3	0.3	0	0	112.9	S223 M224 I228	S223-Q226 WeakPolarHBondContact O-CB 3.33Å; S223-Q226 PolarHBondContact O-N 3.15Å; M224-Q226 PolarHBondContact O-N 3.38Å; Q226-I228 VanDerWaalsContact C-N 3.3Å; Q226-I228 PolarHBondContact O-N 2.88Å
227	G	93.6	Very high	96.4	Very high	47 Å²	47	43 Å²	43	49%	0.485	24%	0.244	S	C	.	.	G	3₁₀ helix	trans	-83	-0.7	179.2	0	0	0	0	0	114.9	M224 L225	M224-G227 PolarHBondContact O-N 3.2Å; M224-G227 VanDerWaalsContact O-N 3.09Å; L225-G227 PolarHBondContact O-N 3.16Å
228	I	96.8	Very high	96.4	Very high	13 Å²	13	38.5 Å²	38.5	7%	0.067	23%	0.227	C	C	.	.	S	Bend	trans	-114.5	121.9	-176.7	-62.2	160.4	0	0	0	108.4	I103 L150 C153 L225 Q226 L232 I233	I103-I228 HydrophobicContact CD1-CB 3.92Å; I103-I228 HydrophobicContact CD1-CD1 3.77Å; I103-I228 HydrophobicContact CD1-CG1 4.46Å; I103-I228 HydrophobicContact CD1-CG2 3.81Å; L150-I228 HydrophobicContact CB-CD1 4.28Å; L150-I228 HydrophobicContact CD1-CD1 3.89Å; L150-I228 HydrophobicContact CD1-CG2 4.39Å; C153-I228 HydrophobicContact CB-CD1 3.69Å; L225-I228 PolarHBondContact O-N 3.42Å; Q226-I228 VanDerWaalsContact C-N 3.3Å; Q226-I228 PolarHBondContact O-N 2.88Å; I228-L232 HydrophobicContact CG2-CD2 4.28Å; I228-I233 HydrophobicContact CG2-CD1 4.14Å; I228-I233 HydrophobicContact CG2-CG1 4.13Å
229	T	95.7	Very high	96.2	Very high	52 Å²	52	41 Å²	41	32%	0.319	24%	0.236	S	C	.	.			trans	-77.8	142	-174.6	58.3	0	0	0	0	111.4	E140 S231 L232 I233	E140-T229 PolarHBondContact OE1-OG1 3.48Å; E140-T229 VanDerWaalsContact OE1-OG1 3.1Å; E140-T229 PolarHBondContact OE2-OG1 3.39Å; T229-S231 WeakPolarHBondContact CB-OG 3.2Å; T229-S231 PolarHBondContact O-N 3.14Å; T229-S231 PolarHBondContact OG1-OG 3.49Å; T229-L232 PolarHBondContact O-N 3.01Å; T229-L232 VanDerWaalsContact OG1-CB 3.23Å; T229-L232 WeakPolarHBondContact OG1-CB 3.43Å; T229-L232 PolarHBondContact OG1-N 3.48Å; T229-I233 PolarHBondContact O-N 3.06Å
230	P	96.5	Very high	96	Very high	61 Å²	61	42.2 Å²	42.2	40%	0.396	25%	0.247	S	C	.	.	H	α-helix	trans	-59.4	-32.9	173.5	-22.7	32.3	0	0	0	112.9	W98 A99 I233 A234	W98-P230 HydrophobicContact CH2-CB 4.03Å; W98-P230 WeakPolarHBondContact CH2-O 3.28Å; W98-P230 HydrophobicContact CZ2-CB 3.36Å; A99-P230 HydrophobicContact CB-CB 3.87Å; A99-P230 HydrophobicContact CB-CG 3.93Å; P230-I233 PolarHBondContact O-N 2.97Å; P230-A234 WeakPolarHBondContact O-CB 3.39Å; P230-A234 PolarHBondContact O-N 3.42Å
231	S	95.2	Very high	95.9	Very high	44 Å²	44	40.3 Å²	40.3	31%	0.308	24%	0.24	S	C	.	.	H	α-helix	trans	-61.8	-46.1	174.5	35.2	0	0	0	0	112.6	E140 T229 I233 A234 E235	E140-S231 VanDerWaalsContact OE2-CB 3.27Å; E140-S231 WeakPolarHBondContact OE2-CB 3.22Å; E140-S231 PolarHBondContact OE2-OG 3.15Å; T229-S231 WeakPolarHBondContact CB-OG 3.2Å; T229-S231 PolarHBondContact O-N 3.14Å; T229-S231 PolarHBondContact OG1-OG 3.49Å; S231-I233 VanDerWaalsContact C-N 3.25Å; S231-I233 PolarHBondContact O-N 3.16Å; S231-A234 PolarHBondContact O-N 3.48Å; S231-E235 WeakPolarHBondContact O-CB 3.49Å; S231-E235 WeakPolarHBondContact O-CG 3.38Å; S231-E235 PolarHBondContact O-N 2.07Å
232	L	95.8	Very high	95.7	Very high	4 Å²	4	41.9 Å²	41.9	2%	0.021	25%	0.248	C	C	.	.	H	α-helix	trans	-56	-43.2	174.7	172.5	65.4	0	0	0	111.4	P142 G146 V147 I228 T229 L236	P142-L232 HydrophobicContact CB-CD1 3.8Å; P142-L232 HydrophobicContact CG-CD1 4.47Å; G146-L232 VanDerWaalsContact C-CD2 3.45Å; G146-L232 WeakPolarHBondContact O-CD2 3.43Å; V147-L232 HydrophobicContact CG2-CD1 4.37Å; I228-L232 HydrophobicContact CG2-CD2 4.28Å; T229-L232 PolarHBondContact O-N 3.01Å; T229-L232 VanDerWaalsContact OG1-CB 3.23Å; T229-L232 WeakPolarHBondContact OG1-CB 3.43Å; T229-L232 PolarHBondContact OG1-N 3.48Å; L232-L236 WeakPolarHBondContact O-CB 3.45Å; L232-L236 PolarHBondContact O-N 2.87Å
233	I	97.2	Very high	95.4	Very high	0 Å²	0	42.5 Å²	42.5	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-65.9	-48.3	179	-64.5	170.3	0	0	0	110.8	W98 A99 F102 I103 I228 T229 P230 S231 E235 L236 F237 F238	W98-I233 HydrophobicContact CH2-CB 4.27Å; W98-I233 HydrophobicContact CH2-CG2 4.13Å; W98-I233 HydrophobicContact CZ3-CB 4.38Å; W98-I233 HydrophobicContact CZ3-CG2 3.81Å; A99-I233 HydrophobicContact CB-CD1 3.64Å; F102-I233 HydrophobicContact CD1-CD1 4.34Å; F102-I233 HydrophobicContact CD1-CG2 3.4Å; F102-I233 HydrophobicContact CE1-CG2 3.48Å; F102-I233 VanDerWaalsContact CE1-CG2 3.48Å; F102-I233 HydrophobicContact CG-CG2 4.35Å; I103-I233 HydrophobicContact CD1-CD1 3.87Å; I103-I233 HydrophobicContact CG1-CD1 3.83Å; I228-I233 HydrophobicContact CG2-CD1 4.14Å; I228-I233 HydrophobicContact CG2-CG1 4.13Å; T229-I233 PolarHBondContact O-N 3.06Å; P230-I233 PolarHBondContact O-N 2.97Å; S231-I233 VanDerWaalsContact C-N 3.25Å; S231-I233 PolarHBondContact O-N 3.16Å; I233-E235 VanDerWaalsContact C-N 3.33Å; I233-E235 PolarHBondContact O-N 3.28Å; I233-L236 PolarHBondContact O-N 3.32Å; I233-F237 HydrophobicContact CG2-CD2 4.13Å; I233-F237 PolarHBondContact O-N 3.2Å; I233-F238 HydrophobicContact CG2-CD2 4.26Å; I233-F238 HydrophobicContact CG2-CE2 3.83Å
234	A	96.7	Very high	95	Very high	22 Å²	22	44.2 Å²	44.2	18%	0.182	26%	0.257	C	S	.	.	I	π-helix	trans	-57.2	-48	178.5	0	0	0	0	0	111.2	P230 S231 F238 R239 L247	P230-A234 WeakPolarHBondContact O-CB 3.39Å; P230-A234 PolarHBondContact O-N 3.42Å; S231-A234 PolarHBondContact O-N 3.48Å; A234-F238 CarbonylContact O-C 3.51Å; A234-F238 PolarHBondContact O-N 2.06Å; A234-F238 VanDerWaalsContact O-N 3.09Å; A234-R239 PolarHBondContact O-N 3.1Å; A234-L247 HydrophobicContact CB-CD2 3.97Å
235	E	95.1	Very high	94.8	Very high	44 Å²	44	43.3 Å²	43.3	21%	0.206	26%	0.26	C	S	.	.	I	π-helix	trans	-72.6	-33.8	-176.5	-68.9	-69.3	153.7	0	0	112.9	E140 P142 S231 I233 R239	E140-E235 WeakPolarHBondContact O-CG 3.35Å; P142-E235 HydrophobicContact CG-CB 3.8Å; S231-E235 WeakPolarHBondContact O-CB 3.49Å; S231-E235 WeakPolarHBondContact O-CG 3.38Å; S231-E235 PolarHBondContact O-N 2.07Å; I233-E235 VanDerWaalsContact C-N 3.33Å; I233-E235 PolarHBondContact O-N 3.28Å; E235-R239 VanDerWaalsContact O-CB 3.22Å; E235-R239 WeakPolarHBondContact O-CB 3.23Å; E235-R239 VanDerWaalsContact OE2-CD 3.25Å; E235-R239 WeakPolarHBondContact OE2-CD 3.3Å; E235-R239 WeakPolarHBondContact OE2-CG 3.28Å
236	L	96.5	Very high	94.6	Very high	5 Å²	5	46.6 Å²	46.6	3%	0.026	28%	0.278	C	S	.	.	I	π-helix	trans	-79.1	-47.4	179.7	-175.2	63.4	0	0	0	113.1	L55 F113 V115 P142 V147 L150 L232 I233	L55-L236 VanDerWaalsContact CD1-O 3.28Å; L55-L236 WeakPolarHBondContact CD1-O 3.42Å; L55-L236 HydrophobicContact CD2-CD1 3.93Å; L55-L236 HydrophobicContact CD2-CG 4.14Å; L55-L236 HydrophobicContact CG-CD1 3.89Å; L55-L236 HydrophobicContact CG-CG 4.29Å; F113-L236 HydrophobicContact CE2-CD2 3.93Å; F113-L236 HydrophobicContact CZ-CD2 4.36Å; V115-L236 HydrophobicContact CG1-CD1 4.2Å; P142-L236 HydrophobicContact CB-CB 4.48Å; P142-L236 HydrophobicContact CB-CD1 4.3Å; P142-L236 HydrophobicContact CG-CB 4.23Å; V147-L236 HydrophobicContact CG2-CD2 3.98Å; L150-L236 HydrophobicContact CD2-CD2 4.35Å; L232-L236 WeakPolarHBondContact O-CB 3.45Å; L232-L236 PolarHBondContact O-N 2.87Å; I233-L236 PolarHBondContact O-N 3.32Å
237	F	97.6	Very high	94.7	Very high	0 Å²	0	38.8 Å²	38.8	0%	0	24%	0.242	C	C	.	.	I	π-helix	trans	-102.3	-29.5	-168.4	-65.1	-76.5	0	0	0	114.4	L55 V61 C62 A65 F102 L106 F113 L150 I233	L55-F237 HydrophobicContact CD1-CD1 4.39Å; V61-F237 HydrophobicContact CG1-CD1 3.93Å; V61-F237 HydrophobicContact CG1-CE1 3.79Å; C62-F237 PolarHBondContact SG-O 2.88Å; A65-F237 HydrophobicContact CB-CB 3.97Å; A65-F237 HydrophobicContact CB-CD1 3.88Å; A65-F237 HydrophobicContact CB-CG 4.18Å; F102-F237 AromaticContact CE1-CD2 3.86Å; F102-F237 HydrophobicContact CE1-CD2 3.86Å; F102-F237 HydrophobicContact CE1-CE2 4.16Å; F102-F237 HydrophobicContact CE1-CG 4.3Å; F102-F237 HydrophobicContact CZ-CB 4.44Å; F102-F237 HydrophobicContact CZ-CD2 4.26Å; F102-F237 HydrophobicContact CZ-CG 4.23Å; L106-F237 HydrophobicContact CD1-CE2 4.19Å; L106-F237 HydrophobicContact CD1-CZ 3.99Å; F113-F237 HydrophobicContact CD1-CE1 4.01Å; F113-F237 AromaticContact CD1-CZ 3.96Å; F113-F237 HydrophobicContact CD1-CZ 3.96Å; F113-F237 HydrophobicContact CD2-CZ 4.49Å; F113-F237 HydrophobicContact CE1-CE1 4.16Å; F113-F237 AromaticContact CE1-CZ 3.62Å; F113-F237 HydrophobicContact CE1-CZ 3.62Å; F113-F237 HydrophobicContact CE2-CZ 4.19Å; F113-F237 HydrophobicContact CG-CE1 4.21Å; F113-F237 HydrophobicContact CG-CZ 4.39Å; F113-F237 HydrophobicContact CZ-CE1 4.49Å; F113-F237 AromaticContact CZ-CZ 3.75Å; F113-F237 HydrophobicContact CZ-CZ 3.75Å; L150-F237 HydrophobicContact CD2-CE2 3.66Å; L150-F237 HydrophobicContact CD2-CZ 3.96Å; I233-F237 HydrophobicContact CG2-CD2 4.13Å; I233-F237 PolarHBondContact O-N 3.2Å
238	F	96.9	Very high	94.8	Very high	3 Å²	3	37.7 Å²	37.7	1%	0.013	22%	0.224	C	C	.	.	I	π-helix	trans	-111.2	-30.5	-168.7	-61.3	-69.1	0	0	0	112.9	A65 L69 F102 I233 A234 P240 V241 I242 L247	A65-F238 HydrophobicContact CB-CE1 4.42Å; A65-F238 HydrophobicContact CB-CZ 4.43Å; L69-F238 HydrophobicContact CB-CE1 3.95Å; L69-F238 HydrophobicContact CB-CZ 3.86Å; L69-F238 HydrophobicContact CD1-CE2 4.35Å; L69-F238 HydrophobicContact CD1-CZ 3.88Å; L69-F238 HydrophobicContact CD2-CD1 4.17Å; L69-F238 HydrophobicContact CD2-CE1 3.59Å; L69-F238 HydrophobicContact CD2-CE2 4.47Å; L69-F238 HydrophobicContact CD2-CZ 3.76Å; L69-F238 HydrophobicContact CG-CE1 4.24Å; L69-F238 HydrophobicContact CG-CZ 4.04Å; F102-F238 HydrophobicContact CD1-CE2 4.49Å; F102-F238 HydrophobicContact CD2-CE2 4.38Å; F102-F238 AromaticContact CD2-CZ 3.96Å; F102-F238 HydrophobicContact CD2-CZ 3.96Å; F102-F238 HydrophobicContact CE1-CE2 4.1Å; F102-F238 HydrophobicContact CE1-CZ 4.32Å; F102-F238 HydrophobicContact CE2-CE2 4.05Å; F102-F238 AromaticContact CE2-CZ 3.46Å; F102-F238 HydrophobicContact CE2-CZ 3.46Å; F102-F238 VanDerWaalsContact CE2-CZ 3.46Å; F102-F238 AromaticContact CZ-CE2 3.87Å; F102-F238 HydrophobicContact CZ-CE2 3.87Å; F102-F238 AromaticContact CZ-CZ 3.64Å; F102-F238 HydrophobicContact CZ-CZ 3.64Å; I233-F238 HydrophobicContact CG2-CD2 4.26Å; I233-F238 HydrophobicContact CG2-CE2 3.83Å; A234-F238 CarbonylContact O-C 3.51Å; A234-F238 PolarHBondContact O-N 2.06Å; A234-F238 VanDerWaalsContact O-N 3.09Å; F238-P240 VanDerWaalsContact C-N 3.32Å; F238-V241 WeakPolarHBondContact O-CA 3.36Å; F238-V241 WeakPolarHBondContact O-CB 2.99Å; F238-V241 PolarHBondContact O-N 3Å; F238-I242 HydrophobicContact CB-CD1 4.26Å; F238-I242 WeakPolarHBondContact O-CG1 3.34Å; F238-I242 PolarHBondContact O-N 3.08Å; F238-L247 HydrophobicContact CB-CD1 4.31Å; F238-L247 HydrophobicContact CB-CD2 4.14Å; F238-L247 HydrophobicContact CD1-CD1 4.43Å; F238-L247 HydrophobicContact CD2-CD1 4.44Å; F238-L247 HydrophobicContact CD2-CD2 3.46Å; F238-L247 VanDerWaalsContact CD2-CD2 3.46Å; F238-L247 HydrophobicContact CE2-CD2 4.05Å; F238-L247 HydrophobicContact CG-CD1 4.13Å; F238-L247 HydrophobicContact CG-CD2 3.88Å
239	R	94	Very high	94.7	Very high	52 Å²	52	42.7 Å²	42.7	20%	0.196	25%	0.248	C	C	.	.	H	α-helix	trans	-49.5	-42.5	174.3	-173.6	75	-146	157	15.5	114.3	A234 E235 V241 G243 Q244	A234-R239 PolarHBondContact O-N 3.1Å; E235-R239 VanDerWaalsContact O-CB 3.22Å; E235-R239 WeakPolarHBondContact O-CB 3.23Å; E235-R239 VanDerWaalsContact OE2-CD 3.25Å; E235-R239 WeakPolarHBondContact OE2-CD 3.3Å; E235-R239 WeakPolarHBondContact OE2-CG 3.28Å; R239-V241 PolarHBondContact O-N 3.12Å; R239-G243 VanDerWaalsContact NH1-C 3.34Å; R239-G243 PolarHBondContact NH1-O 3.33Å; R239-G243 PolarHBondContact NH2-O 3.42Å; R239-G243 VanDerWaalsContact NH2-O 3.09Å; R239-G243 PolarHBondContact O-N 3.03Å; R239-Q244 VanDerWaalsContact NH1-CA 3.35Å; R239-Q244 VanDerWaalsContact NH2-CA 3.28Å; R239-Q244 VanDerWaalsContact NH2-CG 3.31Å
240	P	92.6	Very high	94.7	Very high	80 Å²	80	43 Å²	43	52%	0.519	25%	0.247	S	C	.	.	H	α-helix	trans	-66.4	-18.5	177	-21	35.9	0	0	0	113.8	F238	F238-P240 VanDerWaalsContact C-N 3.32Å
241	V	94.4	Very high	94.7	Very high	81 Å²	81	40.2 Å²	40.2	49%	0.491	23%	0.229	S	C	.	.	H	α-helix	trans	-99.9	-52	-175.7	-176.7	0	0	0	0	111.5	C62 F238 R239	C62-V241 HydrophobicContact CB-CG2 3.49Å; C62-V241 VanDerWaalsContact CB-CG2 3.49Å; F238-V241 WeakPolarHBondContact O-CA 3.36Å; F238-V241 WeakPolarHBondContact O-CB 2.99Å; F238-V241 PolarHBondContact O-N 3Å; R239-V241 PolarHBondContact O-N 3.12Å
242	I	93.8	Very high	94.8	Very high	46 Å²	46	39.7 Å²	39.7	24%	0.236	22%	0.223	C	C	.	.	H	α-helix	trans	-93.5	-5.5	-169.4	75.1	179.6	0	0	0	113	F238 Q244 A245 L247 L250	F238-I242 HydrophobicContact CB-CD1 4.26Å; F238-I242 WeakPolarHBondContact O-CG1 3.34Å; F238-I242 PolarHBondContact O-N 3.08Å; I242-Q244 PolarHBondContact O-N 3.21Å; I242-A245 HydrophobicContact CB-CB 4.16Å; I242-A245 HydrophobicContact CD1-CB 4.4Å; I242-A245 WeakPolarHBondContact CD1-O 3.14Å; I242-A245 HydrophobicContact CG1-CB 4.27Å; I242-A245 WeakPolarHBondContact O-CB 3.03Å; I242-A245 PolarHBondContact O-N 2.82Å; I242-L247 HydrophobicContact CD1-CB 3.89Å; I242-L247 HydrophobicContact CD1-CD1 4.15Å; I242-L250 HydrophobicContact CB-CD1 4.13Å; I242-L250 HydrophobicContact CD1-CD1 3.98Å; I242-L250 HydrophobicContact CG2-CD1 3.9Å
243	G	91.6	Very high	94.7	Very high	30 Å²	30	43.6 Å²	43.6	31%	0.309	25%	0.245	S	C	.	.	T	Hydrogen-bonded Turn	trans	53.8	-136	-175.6	0	0	0	0	0	110.5	R239 A245	R239-G243 VanDerWaalsContact NH1-C 3.34Å; R239-G243 PolarHBondContact NH1-O 3.33Å; R239-G243 PolarHBondContact NH2-O 3.42Å; R239-G243 VanDerWaalsContact NH2-O 3.09Å; R239-G243 PolarHBondContact O-N 3.03Å; G243-A245 PolarHBondContact O-N 3.07Å
244	Q	88.8	Confident	94.5	Very high	97 Å²	97	45.8 Å²	45.8	45%	0.453	26%	0.255	S	S	.	.	T	Hydrogen-bonded Turn	trans	-72.5	-0.8	-173.9	-62.8	-65	-4.7	0	0	115.1	R139 R239 I242	R139-Q244 VanDerWaalsContact CZ-OE1 3.28Å; R239-Q244 VanDerWaalsContact NH1-CA 3.35Å; R239-Q244 VanDerWaalsContact NH2-CA 3.28Å; R239-Q244 VanDerWaalsContact NH2-CG 3.31Å; I242-Q244 PolarHBondContact O-N 3.21Å
245	A	92.6	Very high	94.3	Very high	46 Å²	46	45.1 Å²	45.1	38%	0.38	25%	0.249	S	C	.	.	S	Bend	trans	-65.4	149.1	-179.5	0	0	0	0	0	112.9	I242 G243 L247 L250	I242-A245 HydrophobicContact CB-CB 4.16Å; I242-A245 HydrophobicContact CD1-CB 4.4Å; I242-A245 WeakPolarHBondContact CD1-O 3.14Å; I242-A245 HydrophobicContact CG1-CB 4.27Å; I242-A245 WeakPolarHBondContact O-CB 3.03Å; I242-A245 PolarHBondContact O-N 2.82Å; G243-A245 PolarHBondContact O-N 3.07Å; A245-L247 PolarHBondContact O-N 3.15Å; A245-L250 HydrophobicContact CB-CD1 4.21Å
246	N	92.7	Very high	94	Very high	76 Å²	76	47.4 Å²	47.4	41%	0.406	26%	0.258	S	S	.	.			trans	-81.5	112.9	175.7	-176.5	-18.2	0	0	0	109.9	L248 E249 L250	N246-L248 VanDerWaalsContact C-N 3.25Å; N246-L248 PolarHBondContact O-N 3.11Å; N246-L248 WeakPolarHBondContact OD1-CB 3.23Å; N246-L248 PolarHBondContact OD1-N 3.19Å; N246-E249 HydrophobicContact CB-CB 4.09Å; N246-E249 HydrophobicContact CB-CG 3.98Å; N246-E249 PolarHBondContact ND2-OE1 3.48Å; N246-E249 PolarHBondContact O-N 2.96Å; N246-L250 PolarHBondContact O-N 3.47Å
247	L	95.8	Very high	93.4	Very high	12 Å²	12	50.3 Å²	50.3	6%	0.063	28%	0.278	C	S	.	.	H	α-helix	trans	-59.1	-36.3	-179.3	-178.7	60.9	0	0	0	112.6	L69 W98 A234 F238 I242 A245 L250 L251	L69-L247 HydrophobicContact CD2-CD1 3.83Å; W98-L247 HydrophobicContact CH2-CD2 3.63Å; W98-L247 HydrophobicContact CZ2-CD2 4.31Å; W98-L247 HydrophobicContact CZ3-CD2 3.78Å; A234-L247 HydrophobicContact CB-CD2 3.97Å; F238-L247 HydrophobicContact CB-CD1 4.31Å; F238-L247 HydrophobicContact CB-CD2 4.14Å; F238-L247 HydrophobicContact CD1-CD1 4.43Å; F238-L247 HydrophobicContact CD2-CD1 4.44Å; F238-L247 HydrophobicContact CD2-CD2 3.46Å; F238-L247 VanDerWaalsContact CD2-CD2 3.46Å; F238-L247 HydrophobicContact CE2-CD2 4.05Å; F238-L247 HydrophobicContact CG-CD1 4.13Å; F238-L247 HydrophobicContact CG-CD2 3.88Å; I242-L247 HydrophobicContact CD1-CB 3.89Å; I242-L247 HydrophobicContact CD1-CD1 4.15Å; A245-L247 PolarHBondContact O-N 3.15Å; L247-L250 PolarHBondContact O-N 2.9Å; L247-L251 HydrophobicContact CG-CD1 4.2Å; L247-L251 HydrophobicContact CG-CG 4.48Å; L247-L251 VanDerWaalsContact O-CG 3.28Å; L247-L251 WeakPolarHBondContact O-CG 3.46Å; L247-L251 PolarHBondContact O-N 2.81Å
248	L	95.3	Very high	91.6	Very high	23 Å²	23	61.6 Å²	61.6	12%	0.12	32%	0.321	C	S	.	.	H	α-helix	trans	-66.8	-40	179.9	-177.3	62.3	0	0	0	111.3	R95 N246 L251 V252	R95-L248 HydrophobicContact CB-CD1 4.28Å; R95-L248 HydrophobicContact CB-CD2 4.44Å; R95-L248 HydrophobicContact CG-CD1 4.49Å; R95-L248 HydrophobicContact CG-CD2 3.95Å; N246-L248 VanDerWaalsContact C-N 3.25Å; N246-L248 PolarHBondContact O-N 3.11Å; N246-L248 WeakPolarHBondContact OD1-CB 3.23Å; N246-L248 PolarHBondContact OD1-N 3.19Å; L248-L251 WeakPolarHBondContact O-CB 3.46Å; L248-L251 PolarHBondContact O-N 3.02Å; L248-V252 VanDerWaalsContact O-CG2 3.3Å; L248-V252 WeakPolarHBondContact O-CG2 3.47Å; L248-V252 PolarHBondContact O-N 3.45Å
249	E	94.9	Very high	89.2	Confident	119 Å²	119	67.4 Å²	67.4	56%	0.556	35%	0.352	S	S	*	.	H	α-helix	trans	-62.1	-43.8	175.2	-72.4	165.6	-151.8	0	0	111	N246 L251 V252 D253	N246-E249 HydrophobicContact CB-CB 4.09Å; N246-E249 HydrophobicContact CB-CG 3.98Å; N246-E249 PolarHBondContact ND2-OE1 3.48Å; N246-E249 PolarHBondContact O-N 2.96Å; E249-L251 VanDerWaalsContact C-N 3.29Å; E249-L251 PolarHBondContact O-N 3.39Å; E249-V252 WeakPolarHBondContact O-CB 3.23Å; E249-V252 PolarHBondContact O-N 3.02Å; E249-D253 PolarHBondContact O-N 3.24Å
250	L	95.6	Very high	86.7	Confident	59 Å²	59	74.3 Å²	74.3	31%	0.309	40%	0.403	S	S	.	.	H	α-helix	trans	-61.2	-37.8	174.7	-63.4	175.8	0	0	0	112.4	I242 A245 N246 L247 D253 M254	I242-L250 HydrophobicContact CB-CD1 4.13Å; I242-L250 HydrophobicContact CD1-CD1 3.98Å; I242-L250 HydrophobicContact CG2-CD1 3.9Å; A245-L250 HydrophobicContact CB-CD1 4.21Å; N246-L250 PolarHBondContact O-N 3.47Å; L247-L250 PolarHBondContact O-N 2.9Å; L250-D253 PolarHBondContact O-N 2.97Å; L250-M254 HydrophobicContact CB-CE 4.2Å; L250-M254 WeakPolarHBondContact O-CB 3.44Å; L250-M254 VanDerWaalsContact O-CE 3.31Å; L250-M254 WeakPolarHBondContact O-CE 3.24Å; L250-M254 VanDerWaalsContact O-CG 3.29Å; L250-M254 WeakPolarHBondContact O-CG 3.38Å; L250-M254 PolarHBondContact O-N 3.26Å
251	L	96.6	Very high	86.4	Confident	1 Å²	1	74 Å²	74	1%	0.005	40%	0.398	C	S	.	.	H	α-helix	trans	-65.5	-40.8	175.6	-72.9	169.9	0	0	0	112.3	L69 V73 L94 W98 L247 L248 E249 M254 L255	L69-L251 HydrophobicContact CD1-CD2 3.87Å; L69-L251 HydrophobicContact CD2-CD2 3.96Å; L69-L251 HydrophobicContact CG-CD2 3.88Å; V73-L251 HydrophobicContact CG2-CD2 3.42Å; V73-L251 VanDerWaalsContact CG2-CD2 3.42Å; L94-L251 HydrophobicContact CD2-CB 4.12Å; W98-L251 HydrophobicContact CB-CD1 3.87Å; W98-L251 HydrophobicContact CD2-CD1 3.67Å; W98-L251 HydrophobicContact CE3-CD1 3.97Å; W98-L251 HydrophobicContact CG-CD1 3.64Å; L247-L251 HydrophobicContact CG-CD1 4.2Å; L247-L251 HydrophobicContact CG-CG 4.48Å; L247-L251 VanDerWaalsContact O-CG 3.28Å; L247-L251 WeakPolarHBondContact O-CG 3.46Å; L247-L251 PolarHBondContact O-N 2.81Å; L248-L251 WeakPolarHBondContact O-CB 3.46Å; L248-L251 PolarHBondContact O-N 3.02Å; E249-L251 VanDerWaalsContact C-N 3.29Å; E249-L251 PolarHBondContact O-N 3.39Å; L251-M254 HydrophobicContact CD2-CE 3.86Å; L251-M254 HydrophobicContact CG-CE 4.33Å; L251-M254 PolarHBondContact O-N 3.24Å; L251-L255 WeakPolarHBondContact O-CB 3.24Å; L251-L255 PolarHBondContact O-N 3.49Å
252	V	95.5	Very high	86	Confident	33 Å²	33	73.6 Å²	73.6	20%	0.2	39%	0.393	C	S	.	.	H	α-helix	trans	-61.4	-47.9	174.3	171.1	0	0	0	0	110	Y91 L94 L248 E249 M254 L255 F256	Y91-V252 HydrophobicContact CD2-CG2 3.58Å; Y91-V252 HydrophobicContact CE2-CG2 3.59Å; L94-V252 HydrophobicContact CD2-CG2 3.93Å; L248-V252 VanDerWaalsContact O-CG2 3.3Å; L248-V252 WeakPolarHBondContact O-CG2 3.47Å; L248-V252 PolarHBondContact O-N 3.45Å; E249-V252 WeakPolarHBondContact O-CB 3.23Å; E249-V252 PolarHBondContact O-N 3.02Å; V252-M254 PolarHBondContact O-N 2.91Å; V252-L255 PolarHBondContact O-N 3.01Å; V252-L255 VanDerWaalsContact O-N 3.14Å; V252-F256 HydrophobicContact CG1-CD2 3.69Å; V252-F256 HydrophobicContact CG1-CE2 4Å; V252-F256 VanDerWaalsContact O-CD2 3.25Å; V252-F256 WeakPolarHBondContact O-CD2 3.3Å; V252-F256 PolarHBondContact O-N 3.23Å
253	D	94.1	Very high	85.6	Confident	87 Å²	87	75.2 Å²	75.2	47%	0.465	40%	0.401	S	S	.	.	H	α-helix	trans	-59	-46.6	176.3	-71	-19.7	0	0	0	111.1	E249 L250 L255 F256 C257	E249-D253 PolarHBondContact O-N 3.24Å; L250-D253 PolarHBondContact O-N 2.97Å; D253-L255 VanDerWaalsContact C-N 3.27Å; D253-L255 PolarHBondContact O-N 3.49Å; D253-F256 PolarHBondContact O-N 3.35Å; D253-C257 WeakPolarHBondContact O-CA 3.47Å; D253-C257 WeakPolarHBondContact O-CB 3.44Å; D253-C257 PolarHBondContact O-N 3.14Å
254	M	93.4	Very high	85.2	Confident	45 Å²	45	77.8 Å²	77.8	22%	0.222	41%	0.407	C	S	.	.	H	α-helix	trans	-63.1	-31.5	177.6	-74.1	-175.3	-86.6	0	0	113.5	L69 V70 V73 R77 L250 L251 V252	L69-M254 HydrophobicContact CD2-CE 4.21Å; V70-M254 HydrophobicContact CG2-SD 4.49Å; V73-M254 HydrophobicContact CG1-CB 3.87Å; R77-M254 PolarHBondContact NH1-O 3.44Å; R77-M254 VanDerWaalsContact NH1-O 3.13Å; L250-M254 HydrophobicContact CB-CE 4.2Å; L250-M254 WeakPolarHBondContact O-CB 3.44Å; L250-M254 VanDerWaalsContact O-CE 3.31Å; L250-M254 WeakPolarHBondContact O-CE 3.24Å; L250-M254 VanDerWaalsContact O-CG 3.29Å; L250-M254 WeakPolarHBondContact O-CG 3.38Å; L250-M254 PolarHBondContact O-N 3.26Å; L251-M254 HydrophobicContact CD2-CE 3.86Å; L251-M254 HydrophobicContact CG-CE 4.33Å; L251-M254 PolarHBondContact O-N 3.24Å; V252-M254 PolarHBondContact O-N 2.91Å
255	L	92.8	Very high	85	Confident	8 Å²	8	76.6 Å²	76.6	4%	0.042	40%	0.404	C	S	.	.	H	α-helix	trans	-75.9	-46.1	-179.5	-174.6	65.1	0	0	0	111.6	V73 R77 F82 L94 L251 V252 D253	V73-L255 HydrophobicContact CG1-CB 4.26Å; V73-L255 HydrophobicContact CG1-CD1 4.31Å; R77-L255 HydrophobicContact CB-CD1 3.93Å; R77-L255 VanDerWaalsContact CD-O 3.3Å; R77-L255 WeakPolarHBondContact CD-O 3.35Å; R77-L255 HydrophobicContact CG-CD1 4.33Å; F82-L255 HydrophobicContact CE1-CD1 4.08Å; F82-L255 HydrophobicContact CE1-CD2 4.02Å; F82-L255 HydrophobicContact CZ-CD2 4.21Å; L94-L255 HydrophobicContact CB-CD2 4.2Å; L94-L255 HydrophobicContact CD1-CD2 4.43Å; L94-L255 HydrophobicContact CD2-CB 4.38Å; L94-L255 HydrophobicContact CD2-CD2 3.83Å; L94-L255 HydrophobicContact CG-CD2 4.37Å; L251-L255 WeakPolarHBondContact O-CB 3.24Å; L251-L255 PolarHBondContact O-N 3.49Å; V252-L255 PolarHBondContact O-N 3.01Å; V252-L255 VanDerWaalsContact O-N 3.14Å; D253-L255 VanDerWaalsContact C-N 3.27Å; D253-L255 PolarHBondContact O-N 3.49Å
256	F	89.6	Confident	84.5	Confident	92 Å²	92	78.7 Å²	78.7	40%	0.404	41%	0.406	S	S	.	.	H	α-helix	trans	-99.7	-26	-171.5	-62.5	-67.1	0	0	0	114.5	Q90 V252 D253	Q90-F256 HydrophobicContact CB-CE1 4.25Å; Q90-F256 HydrophobicContact CB-CZ 4Å; V252-F256 HydrophobicContact CG1-CD2 3.69Å; V252-F256 HydrophobicContact CG1-CE2 4Å; V252-F256 VanDerWaalsContact O-CD2 3.25Å; V252-F256 WeakPolarHBondContact O-CD2 3.3Å; V252-F256 PolarHBondContact O-N 3.23Å; D253-F256 PolarHBondContact O-N 3.35Å
257	C	82.8	Confident	83.9	Confident	67 Å²	67	78.9 Å²	78.9	45%	0.453	41%	0.405	S	S	.	.	S	Bend	trans	-86.3	129.4	175.7	-58.9	0	0	0	0	109.8	D253 N259	D253-C257 WeakPolarHBondContact O-CA 3.47Å; D253-C257 WeakPolarHBondContact O-CB 3.44Å; D253-C257 PolarHBondContact O-N 3.14Å; C257-N259 PolarHBondContact O-N 3.44Å
258	R	59.1	Low	83	Confident	236 Å²	236	84 Å²	84	89%	0.891	43%	0.432	S	S	*	.	P	Polyproline II helix	trans	-66.4	116.2	162.7	-79.3	-178.6	171.2	-177.9	-2.6	106.7
259	N	47.2	Very low	82	Confident	125 Å²	125	89.1 Å²	89.1	67%	0.668	46%	0.458	S	S	*	.	P	Polyproline II helix	trans	-54.8	127.6	157.8	-77.4	-15.9	0	0	0	106.7	C257	C257-N259 PolarHBondContact O-N 3.44Å
260	P	42.1	Very low	80.8	Confident	197 Å²	197	86.4 Å²	86.4	100%	1.279	45%	0.449	S	S	*	.			trans	-58.9	0	-178.2	24.3	-33.4	0	0	0	112.6

Retrieved 260 of 260 residues in 96.1 ms (Link to these results)

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