A0A087XW52_POEFO Loading...

Apolipoprotein L

AlphaFold DB , UniProt , Accession A0A087XW52, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 535 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1I52.2Low62Low185 Ų185119.5 Ų119.595%0.94958%0.576SS**  0118.10-59.6172.6000106.6E5I1-E5 HydrophobicContact CG2-CB 4.44Å
2N60.3Low63.8Low115 Ų115112.6 Ų112.662%0.61554%0.54SS*.  trans-77.9144.3-170.3-142-21.2000109.7H4 E5 Q6N2-H4 PolarHBondContact O-N 2.94Å; N2-E5 HydrophobicContact CB-CG 4.22Å; N2-E5 PolarHBondContact N-OE2 3.17Å; N2-E5 WeakPolarHBondContact O-CB 3.48Å; N2-E5 PolarHBondContact O-N 2.99Å; N2-Q6 PolarHBondContact O-N 3.17Å
3F52.9Low65.5Low171 Ų171108 Ų10875%0.7551%0.514SS*.Hα-helixtrans-55.3-28.1-178-162.1-95.6000112.4K7F3-K7 PolarHBondContact O-N 3.23Å
4H54.5Low67Low151 Ų151110.4 Ų110.470%0.69952%0.515SS*.Hα-helixtrans-73.4-36.6177.3-137.7-41.2000113.7N2 H8N2-H4 PolarHBondContact O-N 2.94Å; H4-H8 PolarHBondContact O-N 3.48Å; H4-H8 VanDerWaalsContact O-N 3.17Å
5E57Low68.5Low119 Ų119110.3 Ų110.356%0.55651%0.508SS*.Hα-helixtrans-69.1-38.7174.9-69.417115300110.5I1 N2 K7 H8 F9I1-E5 HydrophobicContact CG2-CB 4.44Å; N2-E5 HydrophobicContact CB-CG 4.22Å; N2-E5 PolarHBondContact N-OE2 3.17Å; N2-E5 WeakPolarHBondContact O-CB 3.48Å; N2-E5 PolarHBondContact O-N 2.99Å; E5-K7 PolarHBondContact O-N 3.23Å; E5-H8 PolarHBondContact O-N 2.94Å; E5-F9 WeakPolarHBondContact O-CB 3.49Å; E5-F9 PolarHBondContact O-N 2.97Å
6Q59.8Low69.8Low108 Ų108103.4 Ų103.451%0.50548%0.477SS..Hα-helixtrans-64.7-40.7178.7-145.4169.811.400111.7N2 L10N2-Q6 PolarHBondContact O-N 3.17Å; Q6-L10 WeakPolarHBondContact O-CB 3.39Å; Q6-L10 WeakPolarHBondContact O-CD1 3.19Å; Q6-L10 WeakPolarHBondContact O-CG 3.24Å; Q6-L10 PolarHBondContact O-N 3.41Å; Q6-L10 VanDerWaalsContact O-N 3.11Å
7K61.8Low71Confident150 Ų150100.6 Ų100.665%0.65246%0.464SS*.Hα-helixtrans-68.1-34.3174.8-164.8176.6-177.3179.70112.6F3 E5 S11F3-K7 PolarHBondContact O-N 3.23Å; E5-K7 PolarHBondContact O-N 3.23Å; K7-S11 PolarHBondContact O-N 3.18Å
8H63.4Low72.1Confident94 Ų94103.8 Ų103.844%0.43547%0.471SS..Hα-helixtrans-69.1-49.2178.1-155.1-117.2000110.8H4 E5 L10 S11 Y12 E229H4-H8 PolarHBondContact O-N 3.48Å; H4-H8 VanDerWaalsContact O-N 3.17Å; E5-H8 PolarHBondContact O-N 2.94Å; H8-L10 PolarHBondContact O-N 3.49Å; H8-S11 WeakPolarHBondContact O-CA 3.43Å; H8-S11 VanDerWaalsContact O-CB 3.24Å; H8-S11 WeakPolarHBondContact O-CB 3.41Å; H8-S11 PolarHBondContact O-N 3.36Å; H8-Y12 AromaticContact CE1-CE2 3.41Å; H8-Y12 VanDerWaalsContact CE1-CE2 3.41Å; H8-Y12 WeakPolarHBondContact CE1-CE2 3.21Å; H8-Y12 AromaticContact CE1-CZ 3.71Å; H8-Y12 PolarHBondContact CE1-OH 2.99Å; H8-Y12 AromaticContact ND1-CE2 3.39Å; H8-Y12 WeakPolarHBondContact ND1-CE2 3.16Å; H8-Y12 WeakPolarHBondContact O-CD2 2.86Å; H8-Y12 PolarHBondContact O-N 3.25Å; H8-E229 IonicContact CE1-OE1 3.49Å; H8-E229 PolarHBondContact CE1-OE1 3.11Å; H8-E229 IonicContact ND1-OE1 3.36Å; H8-E229 PolarHBondContact ND1-OE1 3.22Å; H8-E229 IonicContact ND1-OE2 3.96Å
9F64.3Low73.1Confident74 Ų74100 Ų10033%0.32546%0.457SS..Hα-helixtrans-58.9-44.5176.4-173.5-97.4000112.7E5 S11 Y12 R13 M232E5-F9 WeakPolarHBondContact O-CB 3.49Å; E5-F9 PolarHBondContact O-N 2.97Å; F9-S11 PolarHBondContact O-N 3.36Å; F9-Y12 PolarHBondContact O-N 3.07Å; F9-R13 PolarHBondContact O-N 2.61Å; F9-R13 VanDerWaalsContact O-N 3.15Å; F9-M232 HydrophobicContact CD2-CE 3.95Å; F9-M232 HydrophobicContact CE1-CE 4.37Å; F9-M232 HydrophobicContact CE2-CE 3.39Å; F9-M232 HydrophobicContact CZ-CE 3.64Å
10L73.8Confident74Confident105 Ų10595 Ų9555%0.5543%0.434SS..Hα-helixtrans-58.6-30.7174.1-73.8167.8000112.7Q6 H8 W14Q6-L10 WeakPolarHBondContact O-CB 3.39Å; Q6-L10 WeakPolarHBondContact O-CD1 3.19Å; Q6-L10 WeakPolarHBondContact O-CG 3.24Å; Q6-L10 PolarHBondContact O-N 3.41Å; Q6-L10 VanDerWaalsContact O-N 3.11Å; H8-L10 PolarHBondContact O-N 3.49Å; L10-W14 WeakPolarHBondContact O-CB 3.17Å; L10-W14 PolarHBondContact O-N 3.15Å; L10-W14 VanDerWaalsContact O-N 3.07Å
11S82.4Confident74.9Confident43 Ų4392 Ų9230%0.30142%0.423SS..Hα-helixtrans-69.8-39.1176.8-176.50000112.9K7 H8 F9 R15K7-S11 PolarHBondContact O-N 3.18Å; H8-S11 WeakPolarHBondContact O-CA 3.43Å; H8-S11 VanDerWaalsContact O-CB 3.24Å; H8-S11 WeakPolarHBondContact O-CB 3.41Å; H8-S11 PolarHBondContact O-N 3.36Å; F9-S11 PolarHBondContact O-N 3.36Å; S11-R15 WeakPolarHBondContact O-CB 3.39Å; S11-R15 WeakPolarHBondContact O-CG 3.44Å; S11-R15 PolarHBondContact O-N 2.72Å; S11-R15 VanDerWaalsContact O-N 3.13Å
12Y83.5Confident76.8Confident36 Ų3687.9 Ų87.914%0.14140%0.4CS..Hα-helixtrans-70.9-43177.2-68.2-86.9000111.5H8 F9 W14 R15 L16 E229 Q233H8-Y12 AromaticContact CE1-CE2 3.41Å; H8-Y12 VanDerWaalsContact CE1-CE2 3.41Å; H8-Y12 WeakPolarHBondContact CE1-CE2 3.21Å; H8-Y12 AromaticContact CE1-CZ 3.71Å; H8-Y12 PolarHBondContact CE1-OH 2.99Å; H8-Y12 AromaticContact ND1-CE2 3.39Å; H8-Y12 WeakPolarHBondContact ND1-CE2 3.16Å; H8-Y12 WeakPolarHBondContact O-CD2 2.86Å; H8-Y12 PolarHBondContact O-N 3.25Å; F9-Y12 PolarHBondContact O-N 3.07Å; Y12-W14 PolarHBondContact O-N 2.9Å; Y12-R15 PolarHBondContact O-N 3.17Å; Y12-R15 VanDerWaalsContact O-N 3.16Å; Y12-L16 PolarHBondContact O-N 3.44Å; Y12-E229 HydrophobicContact CD1-CG 4.19Å; Y12-E229 HydrophobicContact CD2-CG 3.54Å; Y12-E229 HydrophobicContact CE1-CG 4.13Å; Y12-E229 HydrophobicContact CE2-CG 3.47Å; Y12-E229 VanDerWaalsContact CE2-CG 3.47Å; Y12-E229 WeakPolarHBondContact CE2-OE1 3.36Å; Y12-E229 HydrophobicContact CG-CG 3.88Å; Y12-E229 PolarHBondContact OH-OE1 3.13Å; Y12-Q233 HydrophobicContact CD1-CB 4.06Å; Y12-Q233 HydrophobicContact CE1-CB 4.11Å; Y12-Q233 HydrophobicContact CE1-CG 4.2Å
13R85.1Confident78.4Confident53 Ų5382.5 Ų82.520%0.237%0.371CS..Hα-helixtrans-54.8-52.1175.7-167.3-169.3177.9132.7-3.8111.5F9 R15 L16 Q17 S224 D225 M232F9-R13 PolarHBondContact O-N 2.61Å; F9-R13 VanDerWaalsContact O-N 3.15Å; R13-R15 VanDerWaalsContact C-N 3.32Å; R13-R15 PolarHBondContact O-N 2.83Å; R13-L16 PolarHBondContact O-N 2.72Å; R13-Q17 WeakPolarHBondContact O-CB 3.33Å; R13-Q17 VanDerWaalsContact O-CG 3.32Å; R13-Q17 WeakPolarHBondContact O-CG 3.46Å; R13-Q17 PolarHBondContact O-N 3.28Å; R13-S224 WeakPolarHBondContact CG-OG 3.48Å; R13-S224 PolarHBondContact NE-OG 3.23Å; R13-D225 IonicContact CZ-OD1 2.68Å; R13-D225 IonicContact NH1-OD1 3.91Å; R13-D225 PolarHBondContact NH1-OD1 3.48Å; R13-D225 VanDerWaalsContact NH2-CG 3.26Å; R13-D225 IonicContact NH2-OD1 3.77Å; R13-D225 PolarHBondContact NH2-OD1 3.43Å; R13-D225 IonicContact NH2-OD2 2.71Å; R13-D225 PolarHBondContact NH2-OD2 2.67Å; R13-M232 VanDerWaalsContact CA-SD 3.58Å; R13-M232 HydrophobicContact CB-SD 4Å; R13-M232 HydrophobicContact CG-SD 4.35Å
14W87.3Confident80.3Confident142 Ų14274.4 Ų74.454%0.53834%0.336SS..Hα-helixtrans-61.9-39.1178.5178.386.1000112.6L10 Y12 R18L10-W14 WeakPolarHBondContact O-CB 3.17Å; L10-W14 PolarHBondContact O-N 3.15Å; L10-W14 VanDerWaalsContact O-N 3.07Å; Y12-W14 PolarHBondContact O-N 2.9Å; W14-R18 VanDerWaalsContact O-CB 3.26Å; W14-R18 WeakPolarHBondContact O-CB 3.45Å; W14-R18 PolarHBondContact O-N 3.27Å
15R88.9Confident82Confident109 Ų10968.5 Ų68.541%0.41131%0.311SS..Hα-helixtrans-63.5-46.5177-78.1172.4-178.6-175.91.1111.9S11 Y12 R13 T19 T236S11-R15 WeakPolarHBondContact O-CB 3.39Å; S11-R15 WeakPolarHBondContact O-CG 3.44Å; S11-R15 PolarHBondContact O-N 2.72Å; S11-R15 VanDerWaalsContact O-N 3.13Å; Y12-R15 PolarHBondContact O-N 3.17Å; Y12-R15 VanDerWaalsContact O-N 3.16Å; R13-R15 VanDerWaalsContact C-N 3.32Å; R13-R15 PolarHBondContact O-N 2.83Å; R15-T19 VanDerWaalsContact O-CB 3.25Å; R15-T19 WeakPolarHBondContact O-CB 3.44Å; R15-T19 PolarHBondContact O-N 2.97Å; R15-T19 PolarHBondContact O-OG1 3.01Å; R15-T236 HydrophobicContact CB-CG2 4.46Å
16L90.1Very high83.8Confident0 Ų064.2 Ų64.20%029%0.291CS..Hα-helixtrans-61.7-53.6177.2175.662.7000110.3Y12 R13 R18 T19 L20 L227 M232 M235 T236Y12-L16 PolarHBondContact O-N 3.44Å; R13-L16 PolarHBondContact O-N 2.72Å; L16-R18 VanDerWaalsContact C-N 3.35Å; L16-R18 PolarHBondContact O-N 3.48Å; L16-T19 PolarHBondContact O-N 3.41Å; L16-L20 HydrophobicContact CD1-CB 4.47Å; L16-L20 VanDerWaalsContact O-CB 3.27Å; L16-L20 WeakPolarHBondContact O-CB 3.25Å; L16-L20 PolarHBondContact O-N 3.05Å; L16-L227 HydrophobicContact CD2-CD1 3.65Å; L16-M232 HydrophobicContact CB-CB 4.45Å; L16-M232 HydrophobicContact CD2-CB 4.11Å; L16-M232 HydrophobicContact CD2-CG 3.79Å; L16-M235 HydrophobicContact CD1-CB 3.69Å; L16-M235 HydrophobicContact CD2-SD 4.43Å; L16-T236 WeakPolarHBondContact CA-OG1 3.32Å
17Q89.8Confident85.5Confident56 Ų5659.1 Ų59.126%0.26227%0.267SS..Hα-helixtrans-53.8-51.5-179.7-74-179.2-37.100111.2R13 T19 C21 V222R13-Q17 WeakPolarHBondContact O-CB 3.33Å; R13-Q17 VanDerWaalsContact O-CG 3.32Å; R13-Q17 WeakPolarHBondContact O-CG 3.46Å; R13-Q17 PolarHBondContact O-N 3.28Å; Q17-T19 PolarHBondContact O-N 2.98Å; Q17-C21 WeakPolarHBondContact O-CB 3.44Å; Q17-C21 PolarHBondContact O-N 2.75Å; Q17-C21 PolarHBondContact O-SG 3Å; Q17-V222 HydrophobicContact CB-CB 4.37Å; Q17-V222 HydrophobicContact CB-CG1 4.49Å; Q17-V222 HydrophobicContact CG-CB 4Å; Q17-V222 HydrophobicContact CG-CG1 3.91Å; Q17-V222 PolarHBondContact NE2-O 3.47Å
18R90.3Very high86.9Confident157 Ų15752.5 Ų52.559%0.59224%0.239SC*.Hα-helixtrans-60.6-47179.4-177.5178.2178.2-172.40.1112.6W14 L16 Q22W14-R18 VanDerWaalsContact O-CB 3.26Å; W14-R18 WeakPolarHBondContact O-CB 3.45Å; W14-R18 PolarHBondContact O-N 3.27Å; L16-R18 VanDerWaalsContact C-N 3.35Å; L16-R18 PolarHBondContact O-N 3.48Å; R18-Q22 WeakPolarHBondContact O-CB 3.26Å; R18-Q22 PolarHBondContact O-N 3.17Å
19T91.9Very high88.3Confident32 Ų3250.1 Ų50.120%0.19623%0.231CC..Hα-helixtrans-68.8-42.2-174.4-53.60000110.9R15 L16 Q17 Y23 T236 I239 K240R15-T19 VanDerWaalsContact O-CB 3.25Å; R15-T19 WeakPolarHBondContact O-CB 3.44Å; R15-T19 PolarHBondContact O-N 2.97Å; R15-T19 PolarHBondContact O-OG1 3.01Å; L16-T19 PolarHBondContact O-N 3.41Å; Q17-T19 PolarHBondContact O-N 2.98Å; T19-Y23 PolarHBondContact O-N 3.43Å; T19-Y23 VanDerWaalsContact O-N 3.08Å; T19-T236 HydrophobicContact CG2-CG2 4.49Å; T19-I239 HydrophobicContact CG2-CB 3.98Å; T19-I239 HydrophobicContact CG2-CG2 3.64Å; T19-K240 HydrophobicContact CG2-CG 4.01Å
20L91.7Very high89.7Confident0 Ų047.9 Ų47.90%022%0.221CC..Hα-helixtrans-72.3-44.6179.4-174.957.1000112.2L16 Q22 Y23 V24 V133 I139 I140 V222 I239 F519L16-L20 HydrophobicContact CD1-CB 4.47Å; L16-L20 VanDerWaalsContact O-CB 3.27Å; L16-L20 WeakPolarHBondContact O-CB 3.25Å; L16-L20 PolarHBondContact O-N 3.05Å; L20-Q22 VanDerWaalsContact C-N 3.28Å; L20-Q22 PolarHBondContact O-N 2.66Å; L20-Y23 PolarHBondContact O-N 3.16Å; L20-V24 HydrophobicContact CD1-CG2 4.34Å; L20-V24 WeakPolarHBondContact O-CG2 3.36Å; L20-V24 PolarHBondContact O-N 2.91Å; L20-V133 HydrophobicContact CD1-CG1 3.89Å; L20-I139 HydrophobicContact CD2-CG2 3.78Å; L20-I140 HydrophobicContact CD1-CD1 3.83Å; L20-I140 HydrophobicContact CD1-CG1 4.47Å; L20-I140 HydrophobicContact CD2-CD1 3.89Å; L20-I140 HydrophobicContact CD2-CG1 3.65Å; L20-I140 HydrophobicContact CG-CD1 4.01Å; L20-I140 HydrophobicContact CG-CG1 4.11Å; L20-V222 HydrophobicContact CB-CG2 4.19Å; L20-V222 HydrophobicContact CD2-CG1 3.93Å; L20-V222 HydrophobicContact CD2-CG2 3.94Å; L20-V222 HydrophobicContact CG-CG2 4.03Å; L20-I239 HydrophobicContact CD1-CD1 3.65Å; L20-I239 HydrophobicContact CD1-CG1 3.94Å; L20-F519 HydrophobicContact CD1-CE1 4.38Å; L20-F519 HydrophobicContact CD1-CE2 4.47Å; L20-F519 HydrophobicContact CD1-CZ 3.72Å; L20-F519 HydrophobicContact CD2-CE1 4.18Å; L20-F519 HydrophobicContact CD2-CZ 3.89Å; L20-F519 HydrophobicContact CG-CZ 4.46Å
21C91Very high90.6Very high32 Ų3243 Ų4322%0.21620%0.195CC..Hα-helixtrans-56.3-44.2173.5-780000111.1Q17 V24 T25 V222Q17-C21 WeakPolarHBondContact O-CB 3.44Å; Q17-C21 PolarHBondContact O-N 2.75Å; Q17-C21 PolarHBondContact O-SG 3Å; C21-V24 PolarHBondContact O-N 3.26Å; C21-T25 VanDerWaalsContact O-CB 3.29Å; C21-T25 WeakPolarHBondContact O-CB 3.46Å; C21-T25 PolarHBondContact O-N 2.8Å; C21-T25 PolarHBondContact O-OG1 3.32Å; C21-V222 WeakPolarHBondContact SG-CG2 3.32Å
22Q92.1Very high91Very high99 Ų9941 Ų4146%0.46318%0.182SC..Hα-helixtrans-61.2-49.7177.5-172.465.851.600111.2R18 L20 V24 T25 D26R18-Q22 WeakPolarHBondContact O-CB 3.26Å; R18-Q22 PolarHBondContact O-N 3.17Å; L20-Q22 VanDerWaalsContact C-N 3.28Å; L20-Q22 PolarHBondContact O-N 2.66Å; Q22-V24 VanDerWaalsContact C-N 3.3Å; Q22-V24 PolarHBondContact O-N 3.33Å; Q22-T25 PolarHBondContact O-N 2.95Å; Q22-D26 PolarHBondContact NE2-OD1 2.94Å; Q22-D26 PolarHBondContact NE2-OD2 3.39Å; Q22-D26 WeakPolarHBondContact O-CB 3.4Å; Q22-D26 PolarHBondContact O-N 3.36Å
23Y93.9Very high91.4Very high2 Ų241 Ų411%0.00819%0.186CC..Hα-helixtrans-58.5-41-179.5-175.3-94.8000112.9T19 L20 T27 T129 S130 V133 F134 I239 L242 D243 R246T19-Y23 PolarHBondContact O-N 3.43Å; T19-Y23 VanDerWaalsContact O-N 3.08Å; L20-Y23 PolarHBondContact O-N 3.16Å; Y23-T27 PolarHBondContact O-N 3.45Å; Y23-T27 PolarHBondContact O-OG1 3.33Å; Y23-T129 HydrophobicContact CE1-CG2 4.38Å; Y23-S130 PolarHBondContact OH-N 3.05Å; Y23-V133 HydrophobicContact CD1-CG1 3.99Å; Y23-V133 HydrophobicContact CD1-CG2 4.48Å; Y23-V133 HydrophobicContact CE1-CB 4.11Å; Y23-V133 HydrophobicContact CE1-CG1 4.01Å; Y23-V133 HydrophobicContact CE1-CG2 3.89Å; Y23-F134 HydrophobicContact CE1-CE2 4.18Å; Y23-I239 HydrophobicContact CD1-CD1 4.27Å; Y23-I239 HydrophobicContact CD2-CG2 3.94Å; Y23-I239 HydrophobicContact CG-CD1 4.46Å; Y23-I239 HydrophobicContact CG-CG2 3.79Å; Y23-L242 HydrophobicContact CE2-CB 3.75Å; Y23-D243 HydrophobicContact CD2-CB 4.18Å; Y23-R246 VanDerWaalsContact CE1-NH2 3.33Å; Y23-R246 VanDerWaalsContact CE2-NH2 3.33Å; Y23-R246 VanDerWaalsContact CZ-CZ 3.46Å; Y23-R246 PolarHBondContact O-NH1 3.4Å; Y23-R246 VanDerWaalsContact O-NH1 3.08Å; Y23-R246 PolarHBondContact OH-NH2 3.19Å
24V93Very high91.8Very high0 Ų038.5 Ų38.50%018%0.176CC..Hα-helixtrans-68-46.2175.7172.70000111.2L20 C21 Q22 D26 T27 L28 F134 I140 L142 I220L20-V24 HydrophobicContact CD1-CG2 4.34Å; L20-V24 WeakPolarHBondContact O-CG2 3.36Å; L20-V24 PolarHBondContact O-N 2.91Å; C21-V24 PolarHBondContact O-N 3.26Å; Q22-V24 VanDerWaalsContact C-N 3.3Å; Q22-V24 PolarHBondContact O-N 3.33Å; V24-D26 VanDerWaalsContact C-N 3.31Å; V24-D26 PolarHBondContact O-N 3.26Å; V24-T27 WeakPolarHBondContact O-CB 3.4Å; V24-T27 PolarHBondContact O-N 2.86Å; V24-T27 VanDerWaalsContact O-N 3.17Å; V24-L28 HydrophobicContact CG1-CG 4.48Å; V24-L28 WeakPolarHBondContact O-CG 3.49Å; V24-L28 PolarHBondContact O-N 3.48Å; V24-F134 HydrophobicContact CB-CE1 4.4Å; V24-F134 HydrophobicContact CG1-CE1 4.09Å; V24-F134 HydrophobicContact CG2-CE1 3.99Å; V24-F134 HydrophobicContact CG2-CZ 4.16Å; V24-I140 HydrophobicContact CG2-CD1 4.09Å; V24-I140 HydrophobicContact CG2-CG2 4.26Å; V24-L142 HydrophobicContact CG1-CD2 3.79Å; V24-I220 HydrophobicContact CB-CD1 4.48Å; V24-I220 HydrophobicContact CB-CG2 4.39Å; V24-I220 HydrophobicContact CG1-CD1 3.83Å; V24-I220 HydrophobicContact CG1-CG1 4.22Å; V24-I220 HydrophobicContact CG1-CG2 4.02Å
25T91.9Very high91.8Very high28 Ų2833.1 Ų33.117%0.17216%0.157CC..Hα-helixtrans-58.7-44.1178.1-58.50000111.3C21 Q22 T27 L28 T29 A217 I220C21-T25 VanDerWaalsContact O-CB 3.29Å; C21-T25 WeakPolarHBondContact O-CB 3.46Å; C21-T25 PolarHBondContact O-N 2.8Å; C21-T25 PolarHBondContact O-OG1 3.32Å; Q22-T25 PolarHBondContact O-N 2.95Å; T25-T27 PolarHBondContact O-N 2.96Å; T25-L28 PolarHBondContact O-N 2.71Å; T25-T29 WeakPolarHBondContact O-CB 3.16Å; T25-T29 PolarHBondContact O-N 3.34Å; T25-T29 PolarHBondContact O-OG1 3.2Å; T25-A217 HydrophobicContact CG2-CB 3.67Å; T25-I220 VanDerWaalsContact OG1-CD1 3.28Å; T25-I220 WeakPolarHBondContact OG1-CD1 3.32Å
26D93.9Very high91.9Very high29 Ų2932 Ų3216%0.15516%0.159CC..Hα-helixtrans-62.8-43.2177.5-66.7-20000110.7Q22 V24 L28 T29 Y30Q22-D26 PolarHBondContact NE2-OD1 2.94Å; Q22-D26 PolarHBondContact NE2-OD2 3.39Å; Q22-D26 WeakPolarHBondContact O-CB 3.4Å; Q22-D26 PolarHBondContact O-N 3.36Å; V24-D26 VanDerWaalsContact C-N 3.31Å; V24-D26 PolarHBondContact O-N 3.26Å; D26-L28 PolarHBondContact O-N 3.25Å; D26-T29 WeakPolarHBondContact O-CB 3.2Å; D26-T29 PolarHBondContact O-N 2.87Å; D26-Y30 HydrophobicContact CB-CE2 3.99Å; D26-Y30 WeakPolarHBondContact O-CD2 3.47Å; D26-Y30 WeakPolarHBondContact O-CE2 3.35Å; D26-Y30 VanDerWaalsContact O-CG 3.27Å; D26-Y30 PolarHBondContact O-N 2.93Å
27T94.8Very high92Very high0 Ų032.5 Ų32.50%016%0.161CC..Hα-helixtrans-57.1-50.3174.2-55.10000111.5Y23 V24 T25 T29 Y30 M31 L126 T129 F134 V151 I155 R246Y23-T27 PolarHBondContact O-N 3.45Å; Y23-T27 PolarHBondContact O-OG1 3.33Å; V24-T27 WeakPolarHBondContact O-CB 3.4Å; V24-T27 PolarHBondContact O-N 2.86Å; V24-T27 VanDerWaalsContact O-N 3.17Å; T25-T27 PolarHBondContact O-N 2.96Å; T27-T29 VanDerWaalsContact C-N 3.26Å; T27-T29 PolarHBondContact O-N 3.21Å; T27-Y30 PolarHBondContact O-N 3.45Å; T27-M31 HydrophobicContact CG2-SD 4.18Å; T27-M31 WeakPolarHBondContact O-CG 3.39Å; T27-M31 PolarHBondContact O-N 3.08Å; T27-L126 HydrophobicContact CG2-CD2 3.92Å; T27-T129 HydrophobicContact CG2-CG2 4.23Å; T27-F134 HydrophobicContact CG2-CE1 4.47Å; T27-F134 HydrophobicContact CG2-CE2 3.88Å; T27-F134 HydrophobicContact CG2-CZ 3.7Å; T27-F134 WeakPolarHBondContact OG1-CZ 3.23Å; T27-V151 HydrophobicContact CG2-CG1 4.07Å; T27-I155 HydrophobicContact CG2-CD1 4.45Å; T27-R246 PolarHBondContact OG1-NH2 3.44Å
28L92.3Very high91.9Very high11 Ų1131.6 Ų31.66%0.05816%0.155CC..Hα-helixtrans-62.9-34.1179.2-67.5-166.6000111.9V24 T25 D26 M31 A32 P143 I146 V151 I212 I220V24-L28 HydrophobicContact CG1-CG 4.48Å; V24-L28 WeakPolarHBondContact O-CG 3.49Å; V24-L28 PolarHBondContact O-N 3.48Å; T25-L28 PolarHBondContact O-N 2.71Å; D26-L28 PolarHBondContact O-N 3.25Å; L28-M31 HydrophobicContact CD2-CE 4.28Å; L28-M31 HydrophobicContact CD2-SD 3.71Å; L28-M31 WeakPolarHBondContact O-CB 3.45Å; L28-M31 PolarHBondContact O-N 3.46Å; L28-A32 WeakPolarHBondContact O-CB 3.27Å; L28-A32 PolarHBondContact O-N 2.96Å; L28-P143 HydrophobicContact CD1-CG 4.26Å; L28-I146 HydrophobicContact CD1-CD1 4.17Å; L28-I146 HydrophobicContact CD2-CD1 4.26Å; L28-I146 HydrophobicContact CD2-CG2 4.32Å; L28-V151 HydrophobicContact CD2-CG2 4Å; L28-I212 HydrophobicContact CB-CD1 3.99Å; L28-I212 HydrophobicContact CD2-CD1 4.01Å; L28-I212 HydrophobicContact CG-CD1 4.47Å; L28-I212 VanDerWaalsContact O-CD1 3.32Å; L28-I212 WeakPolarHBondContact O-CD1 3.35Å; L28-I220 HydrophobicContact CD1-CD1 4.03Å; L28-I220 HydrophobicContact CD1-CG1 4.39Å
29T92.7Very high91.8Very high44 Ų4430.6 Ų30.627%0.2716%0.157SC..Hα-helixtrans-66-41.6175.4-56.90000111.6T25 D26 T27 A32 T33 M214T25-T29 WeakPolarHBondContact O-CB 3.16Å; T25-T29 PolarHBondContact O-N 3.34Å; T25-T29 PolarHBondContact O-OG1 3.2Å; D26-T29 WeakPolarHBondContact O-CB 3.2Å; D26-T29 PolarHBondContact O-N 2.87Å; T27-T29 VanDerWaalsContact C-N 3.26Å; T27-T29 PolarHBondContact O-N 3.21Å; T29-A32 PolarHBondContact O-N 3.01Å; T29-T33 PolarHBondContact O-N 3.21Å; T29-T33 PolarHBondContact O-OG1 2.86Å; T29-M214 HydrophobicContact CG2-SD 4.34Å
30Y94.1Very high91.8Very high28 Ų2832.5 Ų32.511%0.1117%0.166CC..Hα-helixtrans-66.6-38.9174.1-54.7-40.4000111.8D26 T27 A32 T33 V34 A122 K125 M247D26-Y30 HydrophobicContact CB-CE2 3.99Å; D26-Y30 WeakPolarHBondContact O-CD2 3.47Å; D26-Y30 WeakPolarHBondContact O-CE2 3.35Å; D26-Y30 VanDerWaalsContact O-CG 3.27Å; D26-Y30 PolarHBondContact O-N 2.93Å; T27-Y30 PolarHBondContact O-N 3.45Å; Y30-A32 VanDerWaalsContact C-N 3.34Å; Y30-A32 PolarHBondContact O-N 3.21Å; Y30-T33 WeakPolarHBondContact O-CB 3.45Å; Y30-T33 PolarHBondContact O-N 3.26Å; Y30-V34 WeakPolarHBondContact O-CB 3.43Å; Y30-V34 WeakPolarHBondContact O-CG2 3.49Å; Y30-V34 PolarHBondContact O-N 2.77Å; Y30-A122 HydrophobicContact CD1-CB 4.45Å; Y30-K125 HydrophobicContact CD1-CD 4.13Å; Y30-K125 HydrophobicContact CD2-CB 3.91Å; Y30-K125 HydrophobicContact CD2-CD 4.49Å; Y30-K125 HydrophobicContact CE1-CD 3.62Å; Y30-K125 HydrophobicContact CE2-CB 3.95Å; Y30-K125 HydrophobicContact CE2-CD 4.02Å; Y30-K125 HydrophobicContact CG-CB 4.3Å; Y30-M247 WeakPolarHBondContact OH-CE 3.46Å
31M92.3Very high91.8Very high1 Ų133.5 Ų33.51%0.00517%0.17CC..Hα-helixtrans-60.5-43.5173.5-68.6169.959.900111.7T27 L28 V34 K35 L126 V151 V154 F210 I212T27-M31 HydrophobicContact CG2-SD 4.18Å; T27-M31 WeakPolarHBondContact O-CG 3.39Å; T27-M31 PolarHBondContact O-N 3.08Å; L28-M31 HydrophobicContact CD2-CE 4.28Å; L28-M31 HydrophobicContact CD2-SD 3.71Å; L28-M31 WeakPolarHBondContact O-CB 3.45Å; L28-M31 PolarHBondContact O-N 3.46Å; M31-V34 PolarHBondContact O-N 2.88Å; M31-K35 PolarHBondContact O-N 2.99Å; M31-L126 HydrophobicContact CG-CD1 4.42Å; M31-L126 HydrophobicContact CG-CD2 3.85Å; M31-V151 HydrophobicContact CE-CB 4.34Å; M31-V151 HydrophobicContact CE-CG2 3.94Å; M31-V151 HydrophobicContact SD-CB 4.21Å; M31-V151 HydrophobicContact SD-CG1 3.87Å; M31-V151 HydrophobicContact SD-CG2 3.99Å; M31-V154 HydrophobicContact CE-CB 4.4Å; M31-V154 HydrophobicContact CE-CG2 4.13Å; M31-V154 HydrophobicContact CG-CB 4.34Å; M31-V154 HydrophobicContact CG-CG1 3.81Å; M31-F210 HydrophobicContact CB-CZ 4.38Å; M31-F210 HydrophobicContact CE-CD2 4.41Å; M31-F210 HydrophobicContact CE-CE1 4.04Å; M31-F210 HydrophobicContact CE-CE2 3.49Å; M31-F210 VanDerWaalsContact CE-CE2 3.49Å; M31-F210 HydrophobicContact CE-CZ 3.29Å; M31-I212 HydrophobicContact CB-CD1 3.84Å; M31-I212 HydrophobicContact CE-CD1 4.23Å
32A90.8Very high91.8Very high3 Ų335.7 Ų35.73%0.02519%0.186CC..Hα-helixtrans-61.9-46.5174.800000111.4L28 T29 Y30 V34 K35 D36 I212L28-A32 WeakPolarHBondContact O-CB 3.27Å; L28-A32 PolarHBondContact O-N 2.96Å; T29-A32 PolarHBondContact O-N 3.01Å; Y30-A32 VanDerWaalsContact C-N 3.34Å; Y30-A32 PolarHBondContact O-N 3.21Å; A32-V34 VanDerWaalsContact C-N 3.26Å; A32-V34 PolarHBondContact O-N 3.45Å; A32-K35 WeakPolarHBondContact O-CB 3.44Å; A32-K35 PolarHBondContact O-N 3.39Å; A32-K35 VanDerWaalsContact O-N 3.08Å; A32-D36 PolarHBondContact O-N 3.05Å; A32-I212 HydrophobicContact CB-CG1 4.38Å; A32-I212 HydrophobicContact CB-CG2 4.28Å
33T92.7Very high91.9Very high36 Ų3637.6 Ų37.622%0.22120%0.195CC..Hα-helixtrans-56.5-42176.2-55.20000111.9T29 Y30 F37 T118 A122T29-T33 PolarHBondContact O-N 3.21Å; T29-T33 PolarHBondContact O-OG1 2.86Å; Y30-T33 WeakPolarHBondContact O-CB 3.45Å; Y30-T33 PolarHBondContact O-N 3.26Å; T33-F37 PolarHBondContact O-N 2.88Å; T33-T118 HydrophobicContact CG2-CG2 3.91Å; T33-A122 HydrophobicContact CG2-CB 3.87Å
34V91.4Very high92Very high0 Ų037.8 Ų37.80%020%0.195CC..Hα-helixtrans-64.9-44176.8160.90000111.8Y30 M31 A32 F37 Y38 F119 A122 V123 L126 H204Y30-V34 WeakPolarHBondContact O-CB 3.43Å; Y30-V34 WeakPolarHBondContact O-CG2 3.49Å; Y30-V34 PolarHBondContact O-N 2.77Å; M31-V34 PolarHBondContact O-N 2.88Å; A32-V34 VanDerWaalsContact C-N 3.26Å; A32-V34 PolarHBondContact O-N 3.45Å; V34-F37 PolarHBondContact O-N 3.06Å; V34-Y38 HydrophobicContact CG1-CD2 4.24Å; V34-Y38 HydrophobicContact CG1-CE2 3.38Å; V34-Y38 WeakPolarHBondContact CG1-OH 3.34Å; V34-Y38 WeakPolarHBondContact O-CD2 3.48Å; V34-Y38 PolarHBondContact O-N 2.9Å; V34-F119 HydrophobicContact CB-CD2 4.46Å; V34-F119 HydrophobicContact CB-CE2 4.35Å; V34-F119 HydrophobicContact CG1-CE2 4.03Å; V34-F119 HydrophobicContact CG2-CD2 4.16Å; V34-F119 HydrophobicContact CG2-CE2 4.14Å; V34-A122 HydrophobicContact CG2-CB 3.95Å; V34-V123 HydrophobicContact CG2-CG2 3.73Å; V34-L126 HydrophobicContact CG2-CD1 3.81Å; V34-H204 VanDerWaalsContact CG1-CE1 3.42Å; V34-H204 WeakPolarHBondContact CG1-CE1 3.38Å
35K89.1Confident92Very high29 Ų2940.2 Ų40.213%0.12621%0.206CC..Hα-helixtrans-64.2-47.6177-179.4-178.5169.7-175.70112M31 A32 F37 Y38 E39 F210 D211 I212M31-K35 PolarHBondContact O-N 2.99Å; A32-K35 WeakPolarHBondContact O-CB 3.44Å; A32-K35 PolarHBondContact O-N 3.39Å; A32-K35 VanDerWaalsContact O-N 3.08Å; K35-F37 PolarHBondContact O-N 3.48Å; K35-Y38 WeakPolarHBondContact O-CA 3.3Å; K35-Y38 WeakPolarHBondContact O-CB 3.37Å; K35-Y38 PolarHBondContact O-N 3.33Å; K35-E39 WeakPolarHBondContact CE-OE1 3.28Å; K35-E39 PolarHBondContact O-N 3.16Å; K35-E39 VanDerWaalsContact O-N 3.14Å; K35-F210 PolarHBondContact NZ-O 2.98Å; K35-D211 IonicContact NZ-OD1 3.02Å; K35-I212 HydrophobicContact CB-CG2 4.34Å; K35-I212 HydrophobicContact CD-CG2 3.58Å
36D89.8Confident91.9Very high86 Ų8643.1 Ų43.146%0.4622%0.22SC..Hα-helixtrans-55.6-40.5179.7-68.3-10.9000110.7A32 Y38 E39 I40A32-D36 PolarHBondContact O-N 3.05Å; D36-Y38 PolarHBondContact O-N 3.45Å; D36-E39 PolarHBondContact O-N 3.43Å; D36-I40 PolarHBondContact O-N 3.04Å
37F91.9Very high91.9Very high9 Ų943.9 Ų43.94%0.03923%0.228CC..Hα-helixtrans-65.1-37.5175.2-171.4-100.8000112.9T33 V34 K35 E39 I40 F41 W44 L116 F119T33-F37 PolarHBondContact O-N 2.88Å; V34-F37 PolarHBondContact O-N 3.06Å; K35-F37 PolarHBondContact O-N 3.48Å; F37-E39 VanDerWaalsContact C-N 3.3Å; F37-E39 PolarHBondContact O-N 2.9Å; F37-I40 HydrophobicContact CD2-CD1 4.27Å; F37-I40 HydrophobicContact CD2-CG1 4.35Å; F37-I40 CarbonylContact O-C 3.57Å; F37-I40 WeakPolarHBondContact O-CG1 3.45Å; F37-I40 PolarHBondContact O-N 2.79Å; F37-F41 HydrophobicContact CD1-CD2 4.47Å; F37-F41 AromaticContact CE1-CD2 3.66Å; F37-F41 HydrophobicContact CE1-CD2 3.66Å; F37-F41 HydrophobicContact CE1-CE2 4.39Å; F37-F41 HydrophobicContact CZ-CD2 4.14Å; F37-F41 WeakPolarHBondContact O-CA 3.48Å; F37-F41 WeakPolarHBondContact O-CB 3.35Å; F37-F41 PolarHBondContact O-N 3.21Å; F37-W44 HydrophobicContact CE2-CG 4.22Å; F37-W44 HydrophobicContact CZ-CD2 4.04Å; F37-W44 HydrophobicContact CZ-CE3 4.43Å; F37-W44 HydrophobicContact CZ-CG 4.15Å; F37-L116 HydrophobicContact CE1-CD1 3.84Å; F37-L116 HydrophobicContact CE2-CB 4.48Å; F37-L116 HydrophobicContact CE2-CD1 4.28Å; F37-L116 HydrophobicContact CZ-CB 4.37Å; F37-L116 HydrophobicContact CZ-CD1 3.49Å; F37-L116 VanDerWaalsContact CZ-CD1 3.49Å; F37-F119 HydrophobicContact CB-CB 3.85Å; F37-F119 HydrophobicContact CB-CD2 3.56Å; F37-F119 HydrophobicContact CB-CE2 4.42Å; F37-F119 HydrophobicContact CB-CG 3.95Å; F37-F119 HydrophobicContact CD1-CB 3.88Å; F37-F119 AromaticContact CD1-CD1 3.84Å; F37-F119 HydrophobicContact CD1-CD1 3.84Å; F37-F119 AromaticContact CD1-CD2 3.48Å; F37-F119 HydrophobicContact CD1-CD2 3.48Å; F37-F119 VanDerWaalsContact CD1-CD2 3.48Å; F37-F119 HydrophobicContact CD1-CE1 4.26Å; F37-F119 AromaticContact CD1-CE2 3.92Å; F37-F119 HydrophobicContact CD1-CE2 3.92Å; F37-F119 AromaticContact CD1-CG 3.44Å; F37-F119 HydrophobicContact CD1-CG 3.44Å; F37-F119 VanDerWaalsContact CD1-CG 3.44Å; F37-F119 HydrophobicContact CD1-CZ 4.3Å; F37-F119 HydrophobicContact CD2-CB 3.82Å; F37-F119 HydrophobicContact CD2-CG 4.32Å; F37-F119 HydrophobicContact CE1-CB 4.41Å; F37-F119 AromaticContact CE1-CD1 3.96Å; F37-F119 HydrophobicContact CE1-CD1 3.96Å; F37-F119 HydrophobicContact CE1-CD2 4.4Å; F37-F119 HydrophobicContact CE1-CE1 4.35Å; F37-F119 AromaticContact CE1-CG 3.99Å; F37-F119 HydrophobicContact CE1-CG 3.99Å; F37-F119 HydrophobicContact CE2-CB 4.38Å; F37-F119 HydrophobicContact CG-CB 3.55Å; F37-F119 HydrophobicContact CG-CD1 4.41Å; F37-F119 AromaticContact CG-CD2 3.68Å; F37-F119 HydrophobicContact CG-CD2 3.68Å; F37-F119 AromaticContact CG-CG 3.62Å; F37-F119 HydrophobicContact CG-CG 3.62Å
38Y88.3Confident91.9Very high37 Ų3744.7 Ų44.715%0.14523%0.231CC..Hα-helixtrans-65-34.1176.1-65-34.4000113.3V34 K35 D36 I40 F41 F119 C201 H204 S208V34-Y38 HydrophobicContact CG1-CD2 4.24Å; V34-Y38 HydrophobicContact CG1-CE2 3.38Å; V34-Y38 WeakPolarHBondContact CG1-OH 3.34Å; V34-Y38 WeakPolarHBondContact O-CD2 3.48Å; V34-Y38 PolarHBondContact O-N 2.9Å; K35-Y38 WeakPolarHBondContact O-CA 3.3Å; K35-Y38 WeakPolarHBondContact O-CB 3.37Å; K35-Y38 PolarHBondContact O-N 3.33Å; D36-Y38 PolarHBondContact O-N 3.45Å; Y38-I40 VanDerWaalsContact C-N 3.29Å; Y38-I40 PolarHBondContact O-N 2.75Å; Y38-F41 PolarHBondContact O-N 3.4Å; Y38-F119 HydrophobicContact CD1-CE2 4.45Å; Y38-F119 AromaticContact CE1-CE2 3.61Å; Y38-F119 HydrophobicContact CE1-CE2 3.61Å; Y38-F119 AromaticContact CE1-CZ 3.83Å; Y38-F119 HydrophobicContact CE1-CZ 3.83Å; Y38-F119 AromaticContact CZ-CE2 3.72Å; Y38-F119 WeakPolarHBondContact OH-CE2 3.34Å; Y38-C201 HydrophobicContact CD1-CB 4.04Å; Y38-C201 HydrophobicContact CE1-CB 3.9Å; Y38-C201 VanDerWaalsContact CE1-SG 3.55Å; Y38-H204 AromaticContact CE2-ND1 3.38Å; Y38-H204 WeakPolarHBondContact CE2-ND1 3.35Å; Y38-H204 AromaticContact CZ-CG 3.94Å; Y38-H204 AromaticContact CZ-ND1 3.49Å; Y38-H204 WeakPolarHBondContact OH-CB 3.29Å; Y38-H204 PolarHBondContact OH-ND1 3.4Å; Y38-S208 VanDerWaalsContact CE2-OG 3.31Å; Y38-S208 WeakPolarHBondContact CE2-OG 3.46Å
39E89.1Confident91.6Very high136 Ų13647.6 Ų47.664%0.63624%0.244SC*.Hα-helixtrans-64-37.7176.7-65.3-17517800111.4K35 D36 F37K35-E39 WeakPolarHBondContact CE-OE1 3.28Å; K35-E39 PolarHBondContact O-N 3.16Å; K35-E39 VanDerWaalsContact O-N 3.14Å; D36-E39 PolarHBondContact O-N 3.43Å; F37-E39 VanDerWaalsContact C-N 3.3Å; F37-E39 PolarHBondContact O-N 2.9Å
40I91.9Very high91.3Very high72 Ų7250.5 Ų50.537%0.36926%0.256SS..Hα-helixtrans-93.1-4.5178.768.7169.3000113.8D36 F37 Y38 S42 E43 W44D36-I40 PolarHBondContact O-N 3.04Å; F37-I40 HydrophobicContact CD2-CD1 4.27Å; F37-I40 HydrophobicContact CD2-CG1 4.35Å; F37-I40 CarbonylContact O-C 3.57Å; F37-I40 WeakPolarHBondContact O-CG1 3.45Å; F37-I40 PolarHBondContact O-N 2.79Å; Y38-I40 VanDerWaalsContact C-N 3.29Å; Y38-I40 PolarHBondContact O-N 2.75Å; I40-S42 VanDerWaalsContact C-N 3.28Å; I40-S42 PolarHBondContact O-N 3.27Å; I40-S42 VanDerWaalsContact O-N 3.17Å; I40-E43 PolarHBondContact O-N 3.45Å; I40-W44 PolarHBondContact O-N 3.32Å
41F91.9Very high91.1Very high22 Ų2249.4 Ų49.410%0.09625%0.252CS..Hα-helixtrans-58.4-37.7-169.7177.2-106.6000113.2F37 Y38 W44 K45 A197 N198 C201F37-F41 HydrophobicContact CD1-CD2 4.47Å; F37-F41 AromaticContact CE1-CD2 3.66Å; F37-F41 HydrophobicContact CE1-CD2 3.66Å; F37-F41 HydrophobicContact CE1-CE2 4.39Å; F37-F41 HydrophobicContact CZ-CD2 4.14Å; F37-F41 WeakPolarHBondContact O-CA 3.48Å; F37-F41 WeakPolarHBondContact O-CB 3.35Å; F37-F41 PolarHBondContact O-N 3.21Å; Y38-F41 PolarHBondContact O-N 3.4Å; F41-W44 HydrophobicContact CD2-CE3 4.09Å; F41-W44 AromaticContact CE2-CE3 3.79Å; F41-W44 HydrophobicContact CE2-CE3 3.79Å; F41-W44 AromaticContact CE2-CZ3 3.95Å; F41-W44 HydrophobicContact CE2-CZ3 3.95Å; F41-W44 PolarHBondContact O-N 3.2Å; F41-K45 HydrophobicContact CE1-CD 4.17Å; F41-K45 HydrophobicContact CZ-CB 4.37Å; F41-K45 HydrophobicContact CZ-CD 4.26Å; F41-K45 WeakPolarHBondContact O-CB 3.31Å; F41-K45 PolarHBondContact O-N 3.31Å; F41-A197 HydrophobicContact CE2-CB 4.01Å; F41-N198 HydrophobicContact CE1-CB 4.27Å; F41-N198 HydrophobicContact CZ-CB 3.82Å; F41-C201 HydrophobicContact CD1-CB 4.05Å; F41-C201 HydrophobicContact CD2-CB 4.4Å; F41-C201 WeakPolarHBondContact CD2-SG 3.36Å; F41-C201 HydrophobicContact CE1-CB 4.09Å; F41-C201 HydrophobicContact CE2-CB 4.43Å; F41-C201 VanDerWaalsContact CE2-SG 3.58Å; F41-C201 HydrophobicContact CG-CB 4.23Å; F41-C201 HydrophobicContact CZ-CB 4.3Å
42S90.3Very high90.9Very high78 Ų7851.8 Ų51.855%0.54526%0.261SS..Hα-helixtrans-64-44.1177.9-168.90000111.8I40 K45 D46I40-S42 VanDerWaalsContact C-N 3.28Å; I40-S42 PolarHBondContact O-N 3.27Å; I40-S42 VanDerWaalsContact O-N 3.17Å; S42-K45 PolarHBondContact O-N 3.44Å; S42-D46 VanDerWaalsContact O-CG 3.25Å; S42-D46 PolarHBondContact O-N 3.23Å
43E94.6Very high90.5Very high138 Ų13856 Ų5665%0.64529%0.286SS*.Hα-helixtrans-67.1-45.7177.5-179.3173.3-172.900110.6I40 K45 D46 C47I40-E43 PolarHBondContact O-N 3.45Å; E43-K45 VanDerWaalsContact C-N 3.28Å; E43-K45 PolarHBondContact O-N 2.79Å; E43-D46 PolarHBondContact O-N 2.7Å; E43-C47 PolarHBondContact O-N 3.17Å; E43-C47 PolarHBondContact O-SG 3.01Å; E43-C47 VanDerWaalsContact O-SG 3.37Å
44W96.4Very high90.2Very high6 Ų658.1 Ų58.12%0.02329%0.292CS..Hα-helixtrans-53.7-47.3174.6179.793000111.2F37 I40 F41 C47 R48 G112 L113 L116 A197F37-W44 HydrophobicContact CE2-CG 4.22Å; F37-W44 HydrophobicContact CZ-CD2 4.04Å; F37-W44 HydrophobicContact CZ-CE3 4.43Å; F37-W44 HydrophobicContact CZ-CG 4.15Å; I40-W44 PolarHBondContact O-N 3.32Å; F41-W44 HydrophobicContact CD2-CE3 4.09Å; F41-W44 AromaticContact CE2-CE3 3.79Å; F41-W44 HydrophobicContact CE2-CE3 3.79Å; F41-W44 AromaticContact CE2-CZ3 3.95Å; F41-W44 HydrophobicContact CE2-CZ3 3.95Å; F41-W44 PolarHBondContact O-N 3.2Å; W44-C47 PolarHBondContact O-N 3.37Å; W44-R48 HydrophobicContact CD2-CG 4.14Å; W44-R48 HydrophobicContact CE3-CG 4.32Å; W44-R48 HydrophobicContact CH2-CG 4.01Å; W44-R48 HydrophobicContact CZ2-CG 3.82Å; W44-R48 HydrophobicContact CZ3-CG 4.26Å; W44-R48 WeakPolarHBondContact O-CG 3.36Å; W44-R48 PolarHBondContact O-N 3.37Å; W44-R48 VanDerWaalsContact O-N 3.13Å; W44-G112 PolarHBondContact NE1-O 3.49Å; W44-L113 HydrophobicContact CZ2-CD2 4.43Å; W44-L116 HydrophobicContact CH2-CD2 3.99Å; W44-L116 HydrophobicContact CZ2-CB 3.9Å; W44-L116 HydrophobicContact CZ2-CD1 4.39Å; W44-L116 HydrophobicContact CZ2-CD2 3.77Å; W44-L116 HydrophobicContact CZ2-CG 4.23Å; W44-A197 HydrophobicContact CH2-CB 3.96Å; W44-A197 HydrophobicContact CZ3-CB 3.86Å
45K91.6Very high89.9Confident51 Ų5158.1 Ų58.122%0.22229%0.292CS..Hα-helixtrans-62.3-49.5179177.5175.9179.5-1780111.9F41 S42 E43 C47 R48 E49 I194 N198F41-K45 HydrophobicContact CE1-CD 4.17Å; F41-K45 HydrophobicContact CZ-CB 4.37Å; F41-K45 HydrophobicContact CZ-CD 4.26Å; F41-K45 WeakPolarHBondContact O-CB 3.31Å; F41-K45 PolarHBondContact O-N 3.31Å; S42-K45 PolarHBondContact O-N 3.44Å; E43-K45 VanDerWaalsContact C-N 3.28Å; E43-K45 PolarHBondContact O-N 2.79Å; K45-C47 VanDerWaalsContact C-N 3.28Å; K45-C47 PolarHBondContact O-N 2.86Å; K45-R48 PolarHBondContact O-N 2.87Å; K45-R48 VanDerWaalsContact O-N 3.17Å; K45-E49 WeakPolarHBondContact CE-OE1 3.45Å; K45-E49 HydrophobicContact CG-CG 4.42Å; K45-E49 WeakPolarHBondContact O-CG 3.47Å; K45-E49 PolarHBondContact O-N 2.98Å; K45-I194 HydrophobicContact CG-CG2 3.99Å; K45-N198 PolarHBondContact NZ-OD1 3.21Å
46D89.8Confident89.6Confident89 Ų8959.2 Ų59.248%0.47630%0.299SS..Hα-helixtrans-60-39.4-180-72-13.5000111.4S42 E43 M50S42-D46 VanDerWaalsContact O-CG 3.25Å; S42-D46 PolarHBondContact O-N 3.23Å; E43-D46 PolarHBondContact O-N 2.7Å; D46-M50 WeakPolarHBondContact O-CB 3.28Å; D46-M50 PolarHBondContact O-N 2.86Å
47C93.4Very high89Confident46 Ų4657.7 Ų57.731%0.31130%0.295SS..Hα-helixtrans-60.4-48.8173.9-73.80000112.2E43 W44 K45 M50 E51E43-C47 PolarHBondContact O-N 3.17Å; E43-C47 PolarHBondContact O-SG 3.01Å; E43-C47 VanDerWaalsContact O-SG 3.37Å; W44-C47 PolarHBondContact O-N 3.37Å; K45-C47 VanDerWaalsContact C-N 3.28Å; K45-C47 PolarHBondContact O-N 2.86Å; C47-M50 WeakPolarHBondContact O-CB 3.49Å; C47-M50 PolarHBondContact O-N 2.83Å; C47-E51 WeakPolarHBondContact O-CG 3.37Å; C47-E51 PolarHBondContact O-N 3.19Å
48R96.2Very high88.5Confident17 Ų1757.5 Ų57.56%0.06429%0.294CS..Hα-helixtrans-67.9-36.4180-60.1-57.985.679.3-14112.4W44 K45 M50 E51 Y52 D108 L190 I194W44-R48 HydrophobicContact CD2-CG 4.14Å; W44-R48 HydrophobicContact CE3-CG 4.32Å; W44-R48 HydrophobicContact CH2-CG 4.01Å; W44-R48 HydrophobicContact CZ2-CG 3.82Å; W44-R48 HydrophobicContact CZ3-CG 4.26Å; W44-R48 WeakPolarHBondContact O-CG 3.36Å; W44-R48 PolarHBondContact O-N 3.37Å; W44-R48 VanDerWaalsContact O-N 3.13Å; K45-R48 PolarHBondContact O-N 2.87Å; K45-R48 VanDerWaalsContact O-N 3.17Å; R48-M50 VanDerWaalsContact C-N 3.31Å; R48-M50 PolarHBondContact O-N 2.95Å; R48-E51 WeakPolarHBondContact CD-OE2 3.14Å; R48-E51 IonicContact CZ-OE1 3.33Å; R48-E51 VanDerWaalsContact CZ-OE1 3.26Å; R48-E51 IonicContact CZ-OE2 2.73Å; R48-E51 IonicContact NE-OE1 2.81Å; R48-E51 PolarHBondContact NE-OE1 3.3Å; R48-E51 IonicContact NE-OE2 2.92Å; R48-E51 PolarHBondContact NE-OE2 3.49Å; R48-E51 IonicContact NH2-OE1 2.77Å; R48-E51 PolarHBondContact NH2-OE1 3.38Å; R48-E51 IonicContact NH2-OE2 3.84Å; R48-E51 PolarHBondContact O-N 3.18Å; R48-Y52 PolarHBondContact O-N 2.81Å; R48-D108 PolarHBondContact NH2-O 3.2Å; R48-L190 HydrophobicContact CB-CD1 4.23Å; R48-L190 HydrophobicContact CG-CD1 4.42Å; R48-I194 HydrophobicContact CB-CD1 3.56Å; R48-I194 HydrophobicContact CB-CG1 3.61Å; R48-I194 HydrophobicContact CG-CG1 4.43Å
49E85.1Confident88.2Confident71 Ų7157.4 Ų57.433%0.33229%0.294SS..Hα-helixtrans-64.3-37.6173.4-73-174.3-179.700111.4K45 Y52 V53 I194K45-E49 WeakPolarHBondContact CE-OE1 3.45Å; K45-E49 HydrophobicContact CG-CG 4.42Å; K45-E49 WeakPolarHBondContact O-CG 3.47Å; K45-E49 PolarHBondContact O-N 2.98Å; E49-Y52 WeakPolarHBondContact O-CB 3.4Å; E49-Y52 PolarHBondContact O-N 2.9Å; E49-V53 WeakPolarHBondContact O-CG2 3.4Å; E49-V53 PolarHBondContact O-N 3.49Å; E49-I194 HydrophobicContact CG-CD1 4.01Å; E49-I194 HydrophobicContact CG-CG2 4.34Å
50M86.3Confident87.6Confident105 Ų10555.9 Ų55.952%0.51729%0.287SS..Hα-helixtrans-65.3-42.6173.8-167.6-171.3-47.600112.1D46 C47 R48 V53 K54D46-M50 WeakPolarHBondContact O-CB 3.28Å; D46-M50 PolarHBondContact O-N 2.86Å; C47-M50 WeakPolarHBondContact O-CB 3.49Å; C47-M50 PolarHBondContact O-N 2.83Å; R48-M50 VanDerWaalsContact C-N 3.31Å; R48-M50 PolarHBondContact O-N 2.95Å; M50-V53 PolarHBondContact O-N 2.8Å; M50-K54 WeakPolarHBondContact O-CG 3.46Å; M50-K54 PolarHBondContact O-N 3.45Å
51E90.7Very high86.9Confident6 Ų656 Ų563%0.02829%0.287CS..Hα-helixtrans-61.6-43.1174.8-71.5162.5-166.200112C47 R48 V53 K54 M55 V105 D108 T109 L190C47-E51 WeakPolarHBondContact O-CG 3.37Å; C47-E51 PolarHBondContact O-N 3.19Å; R48-E51 WeakPolarHBondContact CD-OE2 3.14Å; R48-E51 IonicContact CZ-OE1 3.33Å; R48-E51 VanDerWaalsContact CZ-OE1 3.26Å; R48-E51 IonicContact CZ-OE2 2.73Å; R48-E51 IonicContact NE-OE1 2.81Å; R48-E51 PolarHBondContact NE-OE1 3.3Å; R48-E51 IonicContact NE-OE2 2.92Å; R48-E51 PolarHBondContact NE-OE2 3.49Å; R48-E51 IonicContact NH2-OE1 2.77Å; R48-E51 PolarHBondContact NH2-OE1 3.38Å; R48-E51 IonicContact NH2-OE2 3.84Å; R48-E51 PolarHBondContact O-N 3.18Å; E51-V53 VanDerWaalsContact C-N 3.31Å; E51-V53 PolarHBondContact O-N 3.48Å; E51-K54 WeakPolarHBondContact O-CB 3.45Å; E51-K54 PolarHBondContact O-N 3.13Å; E51-K54 VanDerWaalsContact O-N 3.13Å; E51-M55 WeakPolarHBondContact O-CG 3.43Å; E51-M55 PolarHBondContact O-N 3.28Å; E51-V105 HydrophobicContact CB-CG1 3.96Å; E51-V105 HydrophobicContact CG-CG1 4.16Å; E51-D108 WeakPolarHBondContact OE1-CB 3.49Å; E51-T109 WeakPolarHBondContact OE2-CA 3.23Å; E51-T109 WeakPolarHBondContact OE2-CB 3.48Å; E51-T109 PolarHBondContact OE2-OG1 3.04Å; E51-L190 HydrophobicContact CB-CD2 3.93Å
52Y88.8Confident86.2Confident51 Ų5155 Ų5520%0.228%0.283CS..Hα-helixtrans-53.6-48.4171.3169.2-92.2000111.4R48 E49 K54 M55 M56 A187 Q191R48-Y52 PolarHBondContact O-N 2.81Å; E49-Y52 WeakPolarHBondContact O-CB 3.4Å; E49-Y52 PolarHBondContact O-N 2.9Å; Y52-K54 VanDerWaalsContact C-N 3.35Å; Y52-K54 PolarHBondContact O-N 3.01Å; Y52-M55 PolarHBondContact O-N 3.38Å; Y52-M56 HydrophobicContact CD1-CG 4.42Å; Y52-M56 HydrophobicContact CE1-CG 3.95Å; Y52-M56 HydrophobicContact CE2-CG 4.07Å; Y52-M56 WeakPolarHBondContact O-CG 3.19Å; Y52-M56 PolarHBondContact O-N 3.22Å; Y52-A187 HydrophobicContact CD2-CB 3.73Å; Y52-A187 VanDerWaalsContact CD2-O 3.23Å; Y52-A187 WeakPolarHBondContact CD2-O 3.49Å; Y52-A187 HydrophobicContact CE2-CB 3.84Å; Y52-Q191 HydrophobicContact CD2-CB 4.24Å; Y52-Q191 HydrophobicContact CE2-CB 4.24Å
53V81.3Confident85.3Confident92 Ų9252.8 Ų52.856%0.55827%0.265SS*.Hα-helixtrans-61.9-41.6177.4172.40000111.4E49 M50 E51 M56 S57E49-V53 WeakPolarHBondContact O-CG2 3.4Å; E49-V53 PolarHBondContact O-N 3.49Å; M50-V53 PolarHBondContact O-N 2.8Å; E51-V53 VanDerWaalsContact C-N 3.31Å; E51-V53 PolarHBondContact O-N 3.48Å; V53-M56 PolarHBondContact O-N 3.41Å; V53-S57 WeakPolarHBondContact O-CB 3.12Å; V53-S57 PolarHBondContact O-N 3.37Å
54K86.4Confident84.3Confident79 Ų7953 Ų5334%0.34326%0.264SS..Hα-helixtrans-61-46.2175.2-68.6175.2-170.5170.70111.1M50 E51 Y52 M56 S57 I58 V105M50-K54 WeakPolarHBondContact O-CG 3.46Å; M50-K54 PolarHBondContact O-N 3.45Å; E51-K54 WeakPolarHBondContact O-CB 3.45Å; E51-K54 PolarHBondContact O-N 3.13Å; E51-K54 VanDerWaalsContact O-N 3.13Å; Y52-K54 VanDerWaalsContact C-N 3.35Å; Y52-K54 PolarHBondContact O-N 3.01Å; K54-M56 PolarHBondContact O-N 3.42Å; K54-S57 WeakPolarHBondContact O-CB 3.24Å; K54-S57 PolarHBondContact O-N 2.86Å; K54-I58 VanDerWaalsContact O-CG1 3.3Å; K54-I58 WeakPolarHBondContact O-CG1 3.18Å; K54-I58 PolarHBondContact O-N 3.01Å; K54-V105 HydrophobicContact CB-CG1 4.21Å; K54-V105 HydrophobicContact CB-CG2 3.85Å; K54-V105 HydrophobicContact CD-CG2 3.76Å; K54-V105 HydrophobicContact CG-CG2 4.44Å
55M84.8Confident83.1Confident0 Ų055.3 Ų55.30%028%0.276CS..Hα-helixtrans-60.2-43.6176.6-67.6-175.9-164.400111.8E51 Y52 S57 I58 K59 L102 V105 L106 T109 V183 L186 A187 L190E51-M55 WeakPolarHBondContact O-CG 3.43Å; E51-M55 PolarHBondContact O-N 3.28Å; Y52-M55 PolarHBondContact O-N 3.38Å; M55-S57 VanDerWaalsContact C-N 3.34Å; M55-S57 PolarHBondContact O-N 2.75Å; M55-I58 WeakPolarHBondContact O-CB 3.31Å; M55-I58 PolarHBondContact O-N 2.97Å; M55-K59 PolarHBondContact O-N 3.31Å; M55-L102 HydrophobicContact CG-CD1 4.08Å; M55-V105 HydrophobicContact CE-CG1 3.81Å; M55-V105 HydrophobicContact CG-CG1 3.88Å; M55-L106 HydrophobicContact CE-CD2 3.38Å; M55-L106 HydrophobicContact CE-CG 4.28Å; M55-L106 HydrophobicContact SD-CD2 4.26Å; M55-T109 HydrophobicContact CE-CG2 4.46Å; M55-T109 WeakPolarHBondContact CE-OG1 3.48Å; M55-V183 HydrophobicContact CB-CG2 3.94Å; M55-V183 VanDerWaalsContact O-CG2 3.27Å; M55-V183 WeakPolarHBondContact O-CG2 3.49Å; M55-L186 HydrophobicContact SD-CB 4.14Å; M55-A187 HydrophobicContact CB-CB 3.9Å; M55-A187 HydrophobicContact SD-CB 4.23Å; M55-L190 HydrophobicContact CE-CD2 4Å
56M83.1Confident81.9Confident53 Ų5353.9 Ų53.926%0.26127%0.271SS..Hα-helixtrans-66.5-34.9176.8-70.3-57.1-6600112.6Y52 V53 K54 K59 E60 A187Y52-M56 HydrophobicContact CD1-CG 4.42Å; Y52-M56 HydrophobicContact CE1-CG 3.95Å; Y52-M56 HydrophobicContact CE2-CG 4.07Å; Y52-M56 WeakPolarHBondContact O-CG 3.19Å; Y52-M56 PolarHBondContact O-N 3.22Å; V53-M56 PolarHBondContact O-N 3.41Å; K54-M56 PolarHBondContact O-N 3.42Å; M56-K59 HydrophobicContact CE-CD 4.14Å; M56-K59 WeakPolarHBondContact O-CB 3.47Å; M56-K59 PolarHBondContact O-N 3.22Å; M56-K59 HydrophobicContact SD-CD 4.38Å; M56-E60 PolarHBondContact O-N 2.78Å; M56-A187 HydrophobicContact CG-CB 4.21Å; M56-A187 HydrophobicContact SD-CB 3.92Å
57S77.4Confident80.6Confident54 Ų5452.9 Ų52.938%0.37827%0.269SS..Hα-helixtrans-65.8-42.9172.2-171.70000111.8V53 K54 M55 K59 E60 M61V53-S57 WeakPolarHBondContact O-CB 3.12Å; V53-S57 PolarHBondContact O-N 3.37Å; K54-S57 WeakPolarHBondContact O-CB 3.24Å; K54-S57 PolarHBondContact O-N 2.86Å; M55-S57 VanDerWaalsContact C-N 3.34Å; M55-S57 PolarHBondContact O-N 2.75Å; S57-K59 VanDerWaalsContact C-N 3.31Å; S57-K59 PolarHBondContact O-N 3.45Å; S57-E60 PolarHBondContact O-N 2.87Å; S57-M61 WeakPolarHBondContact O-CG 3.44Å; S57-M61 PolarHBondContact O-N 3.45Å
58I81.6Confident78.8Confident4 Ų452.1 Ų52.12%0.02126%0.263CS..Hα-helixtrans-58.8-44.4174-69.2164.3000110.5K54 M55 M61 A62 L98 T101 L102 V105 L180 V183K54-I58 VanDerWaalsContact O-CG1 3.3Å; K54-I58 WeakPolarHBondContact O-CG1 3.18Å; K54-I58 PolarHBondContact O-N 3.01Å; M55-I58 WeakPolarHBondContact O-CB 3.31Å; M55-I58 PolarHBondContact O-N 2.97Å; I58-M61 HydrophobicContact CG1-CE 4.34Å; I58-M61 PolarHBondContact O-N 3.47Å; I58-A62 WeakPolarHBondContact O-CB 3.35Å; I58-A62 PolarHBondContact O-N 3.3Å; I58-L98 HydrophobicContact CG2-CB 4.39Å; I58-L98 HydrophobicContact CG2-CD2 4.5Å; I58-T101 HydrophobicContact CD1-CG2 4.05Å; I58-T101 HydrophobicContact CG1-CG2 4.44Å; I58-L102 HydrophobicContact CD1-CB 4.05Å; I58-L102 HydrophobicContact CD1-CD1 4.2Å; I58-L102 HydrophobicContact CG2-CB 4.4Å; I58-V105 HydrophobicContact CD1-CG2 4.25Å; I58-L180 HydrophobicContact CG2-CD2 3.53Å; I58-V183 HydrophobicContact CG2-CG2 4.34Å
59K82.3Confident76.7Confident36 Ų3652.6 Ų52.616%0.15727%0.266CS..Hα-helixtrans-55-54.1173.5-170.7-162.4179.6-173.50111.2M55 M56 S57 M61 A62 D63 V183 E184M55-K59 PolarHBondContact O-N 3.31Å; M56-K59 HydrophobicContact CE-CD 4.14Å; M56-K59 WeakPolarHBondContact O-CB 3.47Å; M56-K59 PolarHBondContact O-N 3.22Å; M56-K59 HydrophobicContact SD-CD 4.38Å; S57-K59 VanDerWaalsContact C-N 3.31Å; S57-K59 PolarHBondContact O-N 3.45Å; K59-M61 VanDerWaalsContact C-N 3.27Å; K59-M61 PolarHBondContact O-N 3.25Å; K59-A62 PolarHBondContact O-N 3.49Å; K59-A62 VanDerWaalsContact O-N 3.14Å; K59-D63 WeakPolarHBondContact O-CB 3.47Å; K59-D63 VanDerWaalsContact O-CG 3.23Å; K59-D63 PolarHBondContact O-N 3.18Å; K59-V183 HydrophobicContact CB-CG1 3.65Å; K59-V183 HydrophobicContact CG-CG1 3.82Å; K59-E184 HydrophobicContact CD-CB 4.01Å; K59-E184 WeakPolarHBondContact CE-OE2 3.39Å; K59-E184 IonicContact NZ-OE1 2.65Å; K59-E184 PolarHBondContact NZ-OE1 2.81Å; K59-E184 IonicContact NZ-OE2 2.67Å; K59-E184 PolarHBondContact NZ-OE2 3.13Å
60E75.9Confident75.1Confident103 Ų10351 Ų5148%0.48127%0.265SS..Hα-helixtrans-60.9-36.9-178.3-164.7-166.2159.900112.1M56 S57 K64M56-E60 PolarHBondContact O-N 2.78Å; S57-E60 PolarHBondContact O-N 2.87Å; E60-K64 VanDerWaalsContact O-CG 3.3Å; E60-K64 WeakPolarHBondContact O-CG 3.43Å; E60-K64 PolarHBondContact O-N 3.17Å; E60-K64 VanDerWaalsContact O-N 3.1Å; E60-K64 VanDerWaalsContact OE1-CE 3.25Å; E60-K64 WeakPolarHBondContact OE1-CE 3.32Å; E60-K64 IonicContact OE1-NZ 2.77Å; E60-K64 PolarHBondContact OE1-NZ 2.98Å
61M77.3Confident73.6Confident74 Ų7448.8 Ų48.837%0.36525%0.25SS..Hα-helixtrans-68.8-42.7174.8-71.4-171.3-76.200112.3S57 I58 K59 D63 K64 I65 L98S57-M61 WeakPolarHBondContact O-CG 3.44Å; S57-M61 PolarHBondContact O-N 3.45Å; I58-M61 HydrophobicContact CG1-CE 4.34Å; I58-M61 PolarHBondContact O-N 3.47Å; K59-M61 VanDerWaalsContact C-N 3.27Å; K59-M61 PolarHBondContact O-N 3.25Å; M61-D63 VanDerWaalsContact C-N 3.34Å; M61-K64 PolarHBondContact O-N 3.17Å; M61-I65 WeakPolarHBondContact O-CD1 3.05Å; M61-I65 VanDerWaalsContact O-CG1 3.3Å; M61-I65 WeakPolarHBondContact O-CG1 3.38Å; M61-I65 PolarHBondContact O-N 3.41Å; M61-L98 HydrophobicContact CB-CD1 3.84Å; M61-L98 HydrophobicContact CB-CD2 4.05Å; M61-L98 HydrophobicContact CE-CD2 3.68Å; M61-L98 HydrophobicContact SD-CD2 4.11Å
62A77.5Confident71Confident1 Ų153.8 Ų53.81%0.00829%0.286CS..Hα-helixtrans-61-44.2175.500000111I58 K59 K64 I65 D66 F69 L95 L98I58-A62 WeakPolarHBondContact O-CB 3.35Å; I58-A62 PolarHBondContact O-N 3.3Å; K59-A62 PolarHBondContact O-N 3.49Å; K59-A62 VanDerWaalsContact O-N 3.14Å; A62-K64 VanDerWaalsContact C-N 3.32Å; A62-K64 PolarHBondContact O-N 3.47Å; A62-I65 PolarHBondContact O-N 3.08Å; A62-D66 PolarHBondContact O-N 2.96Å; A62-F69 HydrophobicContact CB-CD2 4.17Å; A62-F69 HydrophobicContact CB-CG 4.26Å; A62-L95 HydrophobicContact CB-CD2 4.33Å; A62-L98 HydrophobicContact CB-CD1 4.2Å
63D70.9Confident68.3Low33 Ų3359 Ų5918%0.17631%0.313CS..Hα-helixtrans-57.9-40.9175.2-75-1.4000112.3K59 M61 D66 P67 F69 A70K59-D63 WeakPolarHBondContact O-CB 3.47Å; K59-D63 VanDerWaalsContact O-CG 3.23Å; K59-D63 PolarHBondContact O-N 3.18Å; M61-D63 VanDerWaalsContact C-N 3.34Å; D63-D66 CarbonylContact O-C 3.38Å; D63-P67 VanDerWaalsContact O-CA 3.31Å; D63-P67 WeakPolarHBondContact O-CA 3.48Å; D63-F69 WeakPolarHBondContact OD1-CB 3.19Å; D63-A70 HydrophobicContact CB-CB 3.71Å; D63-A70 VanDerWaalsContact CG-CA 3.48Å; D63-A70 WeakPolarHBondContact OD1-CA 3.16Å; D63-A70 PolarHBondContact OD1-N 2.96Å
64K73.2Confident66Low143 Ų14358 Ų5862%0.62232%0.32SS*.Hα-helixtrans-70.2-37.9176.1-74.8169.2-174164.80113E60 M61 A62E60-K64 VanDerWaalsContact O-CG 3.3Å; E60-K64 WeakPolarHBondContact O-CG 3.43Å; E60-K64 PolarHBondContact O-N 3.17Å; E60-K64 VanDerWaalsContact O-N 3.1Å; E60-K64 VanDerWaalsContact OE1-CE 3.25Å; E60-K64 WeakPolarHBondContact OE1-CE 3.32Å; E60-K64 IonicContact OE1-NZ 2.77Å; E60-K64 PolarHBondContact OE1-NZ 2.98Å; M61-K64 PolarHBondContact O-N 3.17Å; A62-K64 VanDerWaalsContact C-N 3.32Å; A62-K64 PolarHBondContact O-N 3.47Å
65I72.2Confident63.2Low53 Ų5363.8 Ų63.827%0.27235%0.346SS..Hα-helixtrans-74-41.4-179.4-69162.2000110.6M61 A62 A91 K94 L95 L98M61-I65 WeakPolarHBondContact O-CD1 3.05Å; M61-I65 VanDerWaalsContact O-CG1 3.3Å; M61-I65 WeakPolarHBondContact O-CG1 3.38Å; M61-I65 PolarHBondContact O-N 3.41Å; A62-I65 PolarHBondContact O-N 3.08Å; I65-A91 HydrophobicContact CG2-CB 4.04Å; I65-K94 HydrophobicContact CD1-CB 3.92Å; I65-K94 HydrophobicContact CD1-CD 4.45Å; I65-L95 HydrophobicContact CB-CD2 4.15Å; I65-L95 HydrophobicContact CD1-CD2 4.47Å; I65-L95 HydrophobicContact CG2-CD1 4.39Å; I65-L95 HydrophobicContact CG2-CD2 3.88Å; I65-L95 HydrophobicContact CG2-CG 3.84Å; I65-L98 HydrophobicContact CD1-CD1 3.57Å; I65-L98 HydrophobicContact CD1-CG 4.45Å
66D66.2Low60.6Low21 Ų2172.1 Ų72.111%0.11238%0.377CS..  trans-14197-178.6-175.9-4.9000109.4A62 D63 T68 F69 L95 K475A62-D66 PolarHBondContact O-N 2.96Å; D63-D66 CarbonylContact O-C 3.38Å; D66-T68 PolarHBondContact O-N 3.29Å; D66-T68 WeakPolarHBondContact OD1-CB 3.34Å; D66-T68 WeakPolarHBondContact OD1-CG2 3.33Å; D66-T68 PolarHBondContact OD1-N 3.37Å; D66-T68 VanDerWaalsContact OD1-N 3.16Å; D66-T68 PolarHBondContact OD1-OG1 3.43Å; D66-T68 PolarHBondContact OD2-OG1 3.11Å; D66-F69 HydrophobicContact CB-CD2 3.72Å; D66-F69 HydrophobicContact CB-CE2 3.83Å; D66-F69 VanDerWaalsContact O-CD2 3.28Å; D66-F69 WeakPolarHBondContact O-CD2 3.34Å; D66-F69 PolarHBondContact O-N 2.88Å; D66-L95 HydrophobicContact CB-CD1 4.23Å; D66-K475 IonicContact OD1-NZ 3.91Å; D66-K475 PolarHBondContact OD1-NZ 3.45Å; D66-K475 WeakPolarHBondContact OD2-CE 3.2Å; D66-K475 IonicContact OD2-NZ 2.77Å; D66-K475 PolarHBondContact OD2-NZ 3.06Å
67P62.7Low58Low68 Ų6874 Ų7444%0.44239%0.393SS..THydrogen-bonded Turntrans-59.3-5.3-179.5-26.234.8000114.9D63 F69 A70D63-P67 VanDerWaalsContact O-CA 3.31Å; D63-P67 WeakPolarHBondContact O-CA 3.48Å; P67-F69 PolarHBondContact O-N 2.78Å; P67-A70 HydrophobicContact CB-CB 4.49Å; P67-A70 WeakPolarHBondContact O-CB 3.43Å; P67-A70 PolarHBondContact O-N 2.8Å; P67-A70 VanDerWaalsContact O-N 3.12Å
68T55.1Low56Low30 Ų3076.7 Ų76.718%0.18441%0.412CS..THydrogen-bonded Turntrans-69.5-15.1168.664.80000113.5D66 L468 K475D66-T68 PolarHBondContact O-N 3.29Å; D66-T68 WeakPolarHBondContact OD1-CB 3.34Å; D66-T68 WeakPolarHBondContact OD1-CG2 3.33Å; D66-T68 PolarHBondContact OD1-N 3.37Å; D66-T68 VanDerWaalsContact OD1-N 3.16Å; D66-T68 PolarHBondContact OD1-OG1 3.43Å; D66-T68 PolarHBondContact OD2-OG1 3.11Å; T68-L468 HydrophobicContact CG2-CD1 4.39Å; T68-K475 HydrophobicContact CG2-CD 4.12Å
69F52.8Low53.5Low28 Ų2885.1 Ų85.112%0.12345%0.449CS..SBendtrans-81-33164.9-63.9-79.3000111.9A62 D63 D66 P67 R71 L95 L180 H181A62-F69 HydrophobicContact CB-CD2 4.17Å; A62-F69 HydrophobicContact CB-CG 4.26Å; D63-F69 WeakPolarHBondContact OD1-CB 3.19Å; D66-F69 HydrophobicContact CB-CD2 3.72Å; D66-F69 HydrophobicContact CB-CE2 3.83Å; D66-F69 VanDerWaalsContact O-CD2 3.28Å; D66-F69 WeakPolarHBondContact O-CD2 3.34Å; D66-F69 PolarHBondContact O-N 2.88Å; P67-F69 PolarHBondContact O-N 2.78Å; F69-R71 PolarHBondContact O-N 3.26Å; F69-L95 HydrophobicContact CD2-CD2 4.44Å; F69-L95 HydrophobicContact CE2-CD1 4Å; F69-L95 HydrophobicContact CE2-CD2 3.78Å; F69-L95 HydrophobicContact CZ-CD2 4.45Å; F69-L180 HydrophobicContact CD1-CB 4.5Å; F69-L180 HydrophobicContact CE1-CB 3.76Å; F69-L180 HydrophobicContact CZ-CB 4.12Å; F69-H181 AromaticContact CD1-ND1 3.62Å; F69-H181 AromaticContact CE1-CE1 3.27Å; F69-H181 WeakPolarHBondContact CE1-CE1 3.26Å; F69-H181 AromaticContact CE1-CG 3.83Å; F69-H181 AromaticContact CE1-ND1 3.16Å; F69-H181 WeakPolarHBondContact CE1-ND1 3.2Å; F69-H181 AromaticContact CE1-NE2 4Å; F69-H181 AromaticContact CZ-CE1 3.69Å
70A51.4Low51Low38 Ų3888.4 Ų88.431%0.31448%0.475SS..  trans-73.695-178.500000111.4D63 P67D63-A70 HydrophobicContact CB-CB 3.71Å; D63-A70 VanDerWaalsContact CG-CA 3.48Å; D63-A70 WeakPolarHBondContact OD1-CA 3.16Å; D63-A70 PolarHBondContact OD1-N 2.96Å; P67-A70 HydrophobicContact CB-CB 4.49Å; P67-A70 WeakPolarHBondContact O-CB 3.43Å; P67-A70 PolarHBondContact O-N 2.8Å; P67-A70 VanDerWaalsContact O-N 3.12Å
71R55Low49Very low57 Ų5793.2 Ų93.222%0.21550%0.495CS..  trans-104.485.7179-61.9-169.2-178172.53.8110.8F69 G455 F460 F479F69-R71 PolarHBondContact O-N 3.26Å; R71-G455 WeakPolarHBondContact CD-O 3.31Å; R71-G455 PolarHBondContact NH1-O 2.66Å; R71-F460 HydrophobicContact CB-CZ 4.09Å; R71-F460 VanDerWaalsContact CD-CE1 3.4Å; R71-F460 HydrophobicContact CG-CE1 3.87Å; R71-F460 HydrophobicContact CG-CE2 4.37Å; R71-F460 HydrophobicContact CG-CZ 3.51Å; R71-F479 VanDerWaalsContact CZ-CE2 3.5Å; R71-F479 VanDerWaalsContact NH1-CE1 3.34Å; R71-F479 VanDerWaalsContact NH2-CE2 3.26Å
72S35.2Very low46.9Very low112 Ų112100 Ų10078%0.78352%0.518SS*.  trans-138.8149.4165.971.50000112.6
73E31.3Very low44.9Very low161 Ų161104.2 Ų104.275%0.75254%0.543SS*.SBendtrans-30.9119.7-173.9-63177.7151.400117.7
74G34.5Very low43.3Very low70 Ų70109.2 Ų109.272%0.72256%0.564SS**SBendtrans60.962.5132.400000118.1
75K26Very low41.9Very low201 Ų201106.7 Ų106.787%0.87456%0.564SS**  trans-174.8112.1140.4-102.6153.6-174.31780110.1P77K75-P77 WeakPolarHBondContact O-CD 3.2Å
76W30.3Very low40Very low174 Ų174107.9 Ų107.966%0.65958%0.577SS**  trans-108.995165.4-170.6-94.3000109.6
77P29.6Very low39Very low93 Ų93111.9 Ų111.960%0.60460%0.598SS**  trans-89.8103.916211.87.1000108.7K75 F79K75-P77 WeakPolarHBondContact O-CD 3.2Å; P77-F79 PolarHBondContact O-N 3.03Å
78S34.8Very low38.6Very low110 Ų110113.3 Ų113.377%0.76960%0.599SS**SBendtrans56.145.1139.4-49.80000119.3
79F28.4Very low38.7Very low182 Ų182117.7 Ų117.780%0.79862%0.62SS**  trans-115.629.6175.2-113.4-85.9000116.3P77P77-F79 PolarHBondContact O-N 3.03Å
80C31.5Very low39.2Very low105 Ų105122.7 Ų122.771%0.70964%0.642SS**  trans-113.160.8167.5-91.80000111.9
81K32.4Very low40.1Very low203 Ų203122.3 Ų122.388%0.88364%0.639SS**SBendtrans-123.6107.5155.2-92.5-177.3176.51750108.9
82Y33.3Very low40.9Very low216 Ų216125.7 Ų125.785%0.84766%0.657SS**  trans7282.6160.8-123-91.7000116.8K84Y82-K84 PolarHBondContact O-N 3.45Å
83V36.2Very low43.1Very low91 Ų91123.1 Ų123.155%0.55264%0.639SS**  trans-85.7108156.6-170.80000107.6L87 Q88V83-L87 HydrophobicContact CG1-CB 4.06Å; V83-Q88 HydrophobicContact CB-CG 4.23Å; V83-Q88 HydrophobicContact CG1-CG 3.59Å
84K37.7Very low45.7Very low138 Ų138120.1 Ų120.160%0.662%0.623SS**  trans-54.3135.5173.4-126.4173.3-179.8177.90109.3Y82 S86 L87 Q88Y82-K84 PolarHBondContact O-N 3.45Å; K84-S86 PolarHBondContact O-N 3.04Å; K84-L87 HydrophobicContact CB-CD1 4.44Å; K84-L87 PolarHBondContact O-N 2.96Å; K84-Q88 PolarHBondContact O-N 3.31Å
85S43.7Very low48.1Very low90 Ų90118 Ų11863%0.62960%0.595SS**Hα-helixtrans-53.5-26.3-176.649.60000114.9L89S85-L89 PolarHBondContact O-N 3.04Å
86S31.6Very low51Low77 Ų77114.1 Ų114.154%0.53858%0.584SS.*Hα-helixtrans-75-26.1175.258.50000114.5K84K84-S86 PolarHBondContact O-N 3.04Å
87L45.9Very low53.9Low106 Ų106110.2 Ų110.256%0.55558%0.576SS**Hα-helixtrans-80.2-28.3174.8-69.5171.5000111.7V83 K84 A91V83-L87 HydrophobicContact CG1-CB 4.06Å; K84-L87 HydrophobicContact CB-CD1 4.44Å; K84-L87 PolarHBondContact O-N 2.96Å; L87-A91 PolarHBondContact O-N 3.31Å; L87-A91 VanDerWaalsContact O-N 3.12Å
88Q53.2Low56.9Low98 Ų98106.6 Ų106.646%0.45855%0.551SS.*Hα-helixtrans-66.4-45.8174.6-74.2-179.5-24.800112V83 K84 K90 A91 E92V83-Q88 HydrophobicContact CB-CG 4.23Å; V83-Q88 HydrophobicContact CG1-CG 3.59Å; K84-Q88 PolarHBondContact O-N 3.31Å; Q88-K90 VanDerWaalsContact C-N 3.28Å; Q88-K90 PolarHBondContact O-N 3.48Å; Q88-A91 PolarHBondContact O-N 3.16Å; Q88-A91 VanDerWaalsContact O-N 3.08Å; Q88-E92 PolarHBondContact O-N 3.29Å
89L57.6Low59.6Low121 Ų121105.5 Ų105.563%0.63453%0.534SS*.Hα-helixtrans-60.6-37.6177.3-72.6169.7000112.5S85 A91 S93S85-L89 PolarHBondContact O-N 3.04Å; L89-A91 VanDerWaalsContact C-N 3.34Å; L89-S93 WeakPolarHBondContact O-CB 3.49Å; L89-S93 PolarHBondContact O-N 3.36Å; L89-S93 VanDerWaalsContact O-N 3.1Å; L89-S93 PolarHBondContact O-OG 3.47Å
90K63Low62.8Low133 Ų133103.1 Ų103.158%0.57852%0.523SS*.Hα-helixtrans-73.3-24176.5-168.6173.6-177.1176.30113.2Q88 S93 K94Q88-K90 VanDerWaalsContact C-N 3.28Å; Q88-K90 PolarHBondContact O-N 3.48Å; K90-S93 PolarHBondContact O-OG 3.38Å; K90-K94 WeakPolarHBondContact O-CD 3.48Å; K90-K94 WeakPolarHBondContact O-CG 3.33Å
91A70Confident65.9Low31 Ų31101 Ų10126%0.25651%0.507SS..Hα-helixtrans-81.5-43.7174.800000111.1I65 L87 Q88 L89 S93 K94 L95I65-A91 HydrophobicContact CG2-CB 4.04Å; L87-A91 PolarHBondContact O-N 3.31Å; L87-A91 VanDerWaalsContact O-N 3.12Å; Q88-A91 PolarHBondContact O-N 3.16Å; Q88-A91 VanDerWaalsContact O-N 3.08Å; L89-A91 VanDerWaalsContact C-N 3.34Å; A91-S93 PolarHBondContact O-N 3.05Å; A91-K94 PolarHBondContact O-N 3.28Å; A91-L95 WeakPolarHBondContact O-CG 3.45Å; A91-L95 PolarHBondContact O-N 3.29Å
92E73.2Confident68.9Low128 Ų12891.3 Ų91.360%0.59847%0.465SS*.Hα-helixtrans-62-41.6176.4-72.4179.5171.200112Q88 K94 L95 L96Q88-E92 PolarHBondContact O-N 3.29Å; E92-K94 VanDerWaalsContact C-N 3.34Å; E92-K94 PolarHBondContact O-N 3.2Å; E92-L95 PolarHBondContact O-N 3.39Å; E92-L96 PolarHBondContact O-N 2.76Å
93S80.8Confident72Confident57 Ų5782.7 Ų82.740%0.39944%0.438SS..Hα-helixtrans-61.8-42.1175.271.70000112L89 K90 A91 L96 D97L89-S93 WeakPolarHBondContact O-CB 3.49Å; L89-S93 PolarHBondContact O-N 3.36Å; L89-S93 VanDerWaalsContact O-N 3.1Å; L89-S93 PolarHBondContact O-OG 3.47Å; K90-S93 PolarHBondContact O-OG 3.38Å; A91-S93 PolarHBondContact O-N 3.05Å; S93-L96 WeakPolarHBondContact O-CB 3.48Å; S93-L96 PolarHBondContact O-N 3.09Å; S93-D97 VanDerWaalsContact O-CG 3.22Å; S93-D97 PolarHBondContact O-N 2.97Å
94K85.3Confident74.9Confident98 Ų9882.8 Ų82.843%0.42643%0.433SS..Hα-helixtrans-67.6-35.9178.1-74.4176.4174.6-163.40113.3I65 K90 A91 E92 L96 D97 L98I65-K94 HydrophobicContact CD1-CB 3.92Å; I65-K94 HydrophobicContact CD1-CD 4.45Å; K90-K94 WeakPolarHBondContact O-CD 3.48Å; K90-K94 WeakPolarHBondContact O-CG 3.33Å; A91-K94 PolarHBondContact O-N 3.28Å; E92-K94 VanDerWaalsContact C-N 3.34Å; E92-K94 PolarHBondContact O-N 3.2Å; K94-L96 VanDerWaalsContact C-N 3.32Å; K94-D97 PolarHBondContact O-N 3.41Å; K94-L98 WeakPolarHBondContact O-CG 3.19Å; K94-L98 PolarHBondContact O-N 3.04Å
95L84.9Confident77.8Confident26 Ų2676.6 Ų76.614%0.13641%0.406CS..Hα-helixtrans-66.6-38.9174-70.6173.4000110.5A62 I65 D66 F69 A91 E92 L98 E99 L180A62-L95 HydrophobicContact CB-CD2 4.33Å; I65-L95 HydrophobicContact CB-CD2 4.15Å; I65-L95 HydrophobicContact CD1-CD2 4.47Å; I65-L95 HydrophobicContact CG2-CD1 4.39Å; I65-L95 HydrophobicContact CG2-CD2 3.88Å; I65-L95 HydrophobicContact CG2-CG 3.84Å; D66-L95 HydrophobicContact CB-CD1 4.23Å; F69-L95 HydrophobicContact CD2-CD2 4.44Å; F69-L95 HydrophobicContact CE2-CD1 4Å; F69-L95 HydrophobicContact CE2-CD2 3.78Å; F69-L95 HydrophobicContact CZ-CD2 4.45Å; A91-L95 WeakPolarHBondContact O-CG 3.45Å; A91-L95 PolarHBondContact O-N 3.29Å; E92-L95 PolarHBondContact O-N 3.39Å; L95-L98 PolarHBondContact O-N 3.38Å; L95-E99 WeakPolarHBondContact O-CB 3.44Å; L95-E99 PolarHBondContact O-N 3.1Å; L95-L180 HydrophobicContact CB-CD1 4.2Å; L95-L180 HydrophobicContact CD2-CD1 4.06Å; L95-L180 WeakPolarHBondContact O-CD1 3.24Å
96L88.6Confident80.3Confident120 Ų12072.4 Ų72.463%0.62838%0.377SS*.Hα-helixtrans-64.8-40.1174.2-170.1144.6000111.7E92 S93 K94 L98 E99 K100E92-L96 PolarHBondContact O-N 2.76Å; S93-L96 WeakPolarHBondContact O-CB 3.48Å; S93-L96 PolarHBondContact O-N 3.09Å; K94-L96 VanDerWaalsContact C-N 3.32Å; L96-L98 VanDerWaalsContact C-N 3.35Å; L96-L98 PolarHBondContact O-N 2.96Å; L96-E99 PolarHBondContact O-N 2.95Å; L96-K100 PolarHBondContact O-N 3.37Å
97D90.9Very high83.5Confident92 Ų9275.4 Ų75.449%0.49238%0.383SS..Hα-helixtrans-60.8-43.3173.1-64.4-28.9000111.3S93 K94 K100 T101S93-D97 VanDerWaalsContact O-CG 3.22Å; S93-D97 PolarHBondContact O-N 2.97Å; K94-D97 PolarHBondContact O-N 3.41Å; D97-K100 WeakPolarHBondContact O-CB 3.16Å; D97-K100 PolarHBondContact O-N 3.41Å; D97-T101 PolarHBondContact O-N 3.14Å; D97-T101 PolarHBondContact O-OG1 3.1Å
98L91.3Very high85.9Confident16 Ų1674.4 Ų74.48%0.08438%0.378CS..Hα-helixtrans-64.7-38.1175.2-75.9179.5000113.1I58 M61 A62 I65 K94 L95 L96 K100 T101 L102 L180I58-L98 HydrophobicContact CG2-CB 4.39Å; I58-L98 HydrophobicContact CG2-CD2 4.5Å; M61-L98 HydrophobicContact CB-CD1 3.84Å; M61-L98 HydrophobicContact CB-CD2 4.05Å; M61-L98 HydrophobicContact CE-CD2 3.68Å; M61-L98 HydrophobicContact SD-CD2 4.11Å; A62-L98 HydrophobicContact CB-CD1 4.2Å; I65-L98 HydrophobicContact CD1-CD1 3.57Å; I65-L98 HydrophobicContact CD1-CG 4.45Å; K94-L98 WeakPolarHBondContact O-CG 3.19Å; K94-L98 PolarHBondContact O-N 3.04Å; L95-L98 PolarHBondContact O-N 3.38Å; L96-L98 VanDerWaalsContact C-N 3.35Å; L96-L98 PolarHBondContact O-N 2.96Å; L98-K100 VanDerWaalsContact C-N 3.3Å; L98-T101 PolarHBondContact O-N 3.07Å; L98-L102 WeakPolarHBondContact O-CB 3.27Å; L98-L102 PolarHBondContact O-N 3.06Å; L98-L180 HydrophobicContact CB-CD1 4.21Å; L98-L180 HydrophobicContact CB-CD2 4.19Å
99E92.6Very high88Confident88 Ų8869.8 Ų69.841%0.41136%0.356SS..Hα-helixtrans-66-35.6176.4-164.6169.5130.700111.1L95 L96 L102 A103 P178 L180L95-E99 WeakPolarHBondContact O-CB 3.44Å; L95-E99 PolarHBondContact O-N 3.1Å; L96-E99 PolarHBondContact O-N 2.95Å; E99-L102 WeakPolarHBondContact O-CB 3.48Å; E99-L102 PolarHBondContact O-N 2.81Å; E99-A103 PolarHBondContact O-N 3Å; E99-P178 HydrophobicContact CG-CB 4.43Å; E99-P178 WeakPolarHBondContact CG-O 3.09Å; E99-L180 HydrophobicContact CB-CD1 4.25Å; E99-L180 HydrophobicContact CB-CG 4.18Å; E99-L180 HydrophobicContact CG-CG 4.47Å
100K95.4Very high90Very high132 Ų13265.8 Ų65.857%0.57434%0.335SS*.Hα-helixtrans-66-45.9170.9-172.5-173.2173.7-167.10111.9L96 D97 L98 L102 A103 E104L96-K100 PolarHBondContact O-N 3.37Å; D97-K100 WeakPolarHBondContact O-CB 3.16Å; D97-K100 PolarHBondContact O-N 3.41Å; L98-K100 VanDerWaalsContact C-N 3.3Å; K100-L102 PolarHBondContact O-N 3.21Å; K100-A103 WeakPolarHBondContact O-CB 3.23Å; K100-A103 PolarHBondContact O-N 3.4Å; K100-A103 VanDerWaalsContact O-N 3.08Å; K100-E104 WeakPolarHBondContact CE-OE1 3.28Å; K100-E104 PolarHBondContact O-N 3.26Å
101T95.7Very high91.6Very high59 Ų5960.9 Ų60.936%0.36232%0.323SS..Hα-helixtrans-60.3-38.3174.2-56.30000111.3I58 D97 L98 A103 E104 V105I58-T101 HydrophobicContact CD1-CG2 4.05Å; I58-T101 HydrophobicContact CG1-CG2 4.44Å; D97-T101 PolarHBondContact O-N 3.14Å; D97-T101 PolarHBondContact O-OG1 3.1Å; L98-T101 PolarHBondContact O-N 3.07Å; T101-A103 VanDerWaalsContact C-N 3.33Å; T101-E104 PolarHBondContact O-N 2.93Å; T101-V105 WeakPolarHBondContact O-CG2 3.49Å; T101-V105 PolarHBondContact O-N 2.86Å; T101-V105 VanDerWaalsContact O-N 3.08Å
102L96.2Very high92.9Very high0 Ų059.5 Ų59.50%031%0.312CS..Hα-helixtrans-62.5-41.4173.6-179.559.3000111.3M55 I58 L98 E99 K100 E104 V105 L106 P178 L180 V183M55-L102 HydrophobicContact CG-CD1 4.08Å; I58-L102 HydrophobicContact CD1-CB 4.05Å; I58-L102 HydrophobicContact CD1-CD1 4.2Å; I58-L102 HydrophobicContact CG2-CB 4.4Å; L98-L102 WeakPolarHBondContact O-CB 3.27Å; L98-L102 PolarHBondContact O-N 3.06Å; E99-L102 WeakPolarHBondContact O-CB 3.48Å; E99-L102 PolarHBondContact O-N 2.81Å; K100-L102 PolarHBondContact O-N 3.21Å; L102-E104 PolarHBondContact O-N 2.98Å; L102-V105 PolarHBondContact O-N 2.93Å; L102-L106 HydrophobicContact CD1-CD1 3.96Å; L102-L106 HydrophobicContact CD1-CD2 4.46Å; L102-L106 HydrophobicContact CD1-CG 4.01Å; L102-L106 HydrophobicContact CD2-CD1 4.37Å; L102-L106 HydrophobicContact CG-CD1 3.71Å; L102-L106 HydrophobicContact CG-CG 4.22Å; L102-L106 WeakPolarHBondContact O-CB 3.38Å; L102-L106 WeakPolarHBondContact O-CG 3.3Å; L102-L106 PolarHBondContact O-N 3.46Å; L102-P178 HydrophobicContact CG-CB 4.39Å; L102-L180 HydrophobicContact CD2-CD2 4.09Å; L102-V183 HydrophobicContact CD1-CG2 3.85Å; L102-V183 HydrophobicContact CD2-CB 4.19Å; L102-V183 HydrophobicContact CD2-CG2 4.2Å
103A97.8Very high94Very high36 Ų3653.7 Ų53.730%0.29828%0.284SS..Hα-helixtrans-60.3-43.2176.300000112.4E99 K100 T101 L106 E107 P178E99-A103 PolarHBondContact O-N 3Å; K100-A103 WeakPolarHBondContact O-CB 3.23Å; K100-A103 PolarHBondContact O-N 3.4Å; K100-A103 VanDerWaalsContact O-N 3.08Å; T101-A103 VanDerWaalsContact C-N 3.33Å; A103-L106 PolarHBondContact O-N 3.26Å; A103-E107 PolarHBondContact O-N 3.2Å; A103-P178 HydrophobicContact CB-CB 3.73Å; A103-P178 HydrophobicContact CB-CG 3.95Å
104E97.8Very high94.7Very high93 Ų9355.4 Ų55.444%0.43529%0.286SS..Hα-helixtrans-61-44.5175.7-67.9167.1-171.700111.2K100 T101 L102 L106 E107 D108K100-E104 WeakPolarHBondContact CE-OE1 3.28Å; K100-E104 PolarHBondContact O-N 3.26Å; T101-E104 PolarHBondContact O-N 2.93Å; L102-E104 PolarHBondContact O-N 2.98Å; E104-L106 VanDerWaalsContact C-N 3.34Å; E104-L106 PolarHBondContact O-N 3.14Å; E104-E107 PolarHBondContact O-N 2.89Å; E104-D108 PolarHBondContact O-N 2.62Å
105V97.4Very high95.1Very high7 Ų755.6 Ų55.64%0.04229%0.289CS..Hα-helixtrans-62.9-41175.8176.60000111.7E51 K54 M55 I58 T101 L102 E107 D108 T109E51-V105 HydrophobicContact CB-CG1 3.96Å; E51-V105 HydrophobicContact CG-CG1 4.16Å; K54-V105 HydrophobicContact CB-CG1 4.21Å; K54-V105 HydrophobicContact CB-CG2 3.85Å; K54-V105 HydrophobicContact CD-CG2 3.76Å; K54-V105 HydrophobicContact CG-CG2 4.44Å; M55-V105 HydrophobicContact CE-CG1 3.81Å; M55-V105 HydrophobicContact CG-CG1 3.88Å; I58-V105 HydrophobicContact CD1-CG2 4.25Å; T101-V105 WeakPolarHBondContact O-CG2 3.49Å; T101-V105 PolarHBondContact O-N 2.86Å; T101-V105 VanDerWaalsContact O-N 3.08Å; L102-V105 PolarHBondContact O-N 2.93Å; V105-E107 VanDerWaalsContact C-N 3.33Å; V105-D108 PolarHBondContact O-N 2.98Å; V105-T109 PolarHBondContact O-N 3.36Å; V105-T109 PolarHBondContact O-OG1 3.36Å
106L97.8Very high95.6Very high3 Ų354.4 Ų54.42%0.01628%0.282CS..Hα-helixtrans-72.2-28.1-179.5-67168.6000112.4M55 L102 A103 E104 T109 L110 F176 P178 L186M55-L106 HydrophobicContact CE-CD2 3.38Å; M55-L106 HydrophobicContact CE-CG 4.28Å; M55-L106 HydrophobicContact SD-CD2 4.26Å; L102-L106 HydrophobicContact CD1-CD1 3.96Å; L102-L106 HydrophobicContact CD1-CD2 4.46Å; L102-L106 HydrophobicContact CD1-CG 4.01Å; L102-L106 HydrophobicContact CD2-CD1 4.37Å; L102-L106 HydrophobicContact CG-CD1 3.71Å; L102-L106 HydrophobicContact CG-CG 4.22Å; L102-L106 WeakPolarHBondContact O-CB 3.38Å; L102-L106 WeakPolarHBondContact O-CG 3.3Å; L102-L106 PolarHBondContact O-N 3.46Å; A103-L106 PolarHBondContact O-N 3.26Å; E104-L106 VanDerWaalsContact C-N 3.34Å; E104-L106 PolarHBondContact O-N 3.14Å; L106-T109 PolarHBondContact O-N 2.83Å; L106-L110 WeakPolarHBondContact O-CB 3.32Å; L106-L110 WeakPolarHBondContact O-CG 3.21Å; L106-L110 PolarHBondContact O-N 2.93Å; L106-F176 HydrophobicContact CD2-CB 3.93Å; L106-F176 HydrophobicContact CD2-CD1 3.68Å; L106-F176 HydrophobicContact CD2-CG 4.28Å; L106-P178 VanDerWaalsContact CD1-CA 3.49Å; L106-P178 HydrophobicContact CD1-CB 3.98Å; L106-L186 HydrophobicContact CD1-CD1 3.97Å; L106-L186 HydrophobicContact CD2-CD1 3.93Å
107E97.9Very high96Very high140 Ų14052.4 Ų52.465%0.65427%0.272SS*.Hα-helixtrans-63.7-48.4171.6-172.7174-176.100110.6A103 E104 V105 T109 L110 G111A103-E107 PolarHBondContact O-N 3.2Å; E104-E107 PolarHBondContact O-N 2.89Å; V105-E107 VanDerWaalsContact C-N 3.33Å; E107-T109 VanDerWaalsContact C-N 3.33Å; E107-T109 PolarHBondContact O-N 3.35Å; E107-L110 PolarHBondContact O-N 2.96Å; E107-G111 PolarHBondContact O-N 2.96Å
108D97.1Very high96.2Very high85 Ų8552.1 Ų52.146%0.45527%0.274SS..Hα-helixtrans-58.9-44.6173.3-66.5-21.8000111.2R48 E51 E104 V105 L110 G111 G112R48-D108 PolarHBondContact NH2-O 3.2Å; E51-D108 WeakPolarHBondContact OE1-CB 3.49Å; E104-D108 PolarHBondContact O-N 2.62Å; V105-D108 PolarHBondContact O-N 2.98Å; D108-L110 PolarHBondContact O-N 2.9Å; D108-G111 PolarHBondContact O-N 3.18Å; D108-G112 PolarHBondContact O-N 2.84Å
109T97.5Very high96.4Very high0 Ų051.4 Ų51.40%027%0.27CS..Hα-helixtrans-59.2-46.6176.5-62.30000111.6E51 M55 V105 L106 E107 G112 L113 F176 L190E51-T109 WeakPolarHBondContact OE2-CA 3.23Å; E51-T109 WeakPolarHBondContact OE2-CB 3.48Å; E51-T109 PolarHBondContact OE2-OG1 3.04Å; M55-T109 HydrophobicContact CE-CG2 4.46Å; M55-T109 WeakPolarHBondContact CE-OG1 3.48Å; V105-T109 PolarHBondContact O-N 3.36Å; V105-T109 PolarHBondContact O-OG1 3.36Å; L106-T109 PolarHBondContact O-N 2.83Å; E107-T109 VanDerWaalsContact C-N 3.33Å; E107-T109 PolarHBondContact O-N 3.35Å; T109-G112 PolarHBondContact O-N 2.98Å; T109-L113 HydrophobicContact CG2-CD1 4.08Å; T109-L113 HydrophobicContact CG2-CG 4.35Å; T109-L113 VanDerWaalsContact O-CG 3.32Å; T109-L113 WeakPolarHBondContact O-CG 3.48Å; T109-L113 PolarHBondContact O-N 3.37Å; T109-F176 HydrophobicContact CG2-CD1 4.38Å; T109-F176 HydrophobicContact CG2-CE1 4.39Å; T109-L190 HydrophobicContact CG2-CD1 3.81Å; T109-L190 HydrophobicContact CG2-CD2 4.09Å
110L98Very high96.6Very high37 Ų3747.5 Ų47.519%0.19425%0.252CS..Hα-helixtrans-64.6-40.4-179.9-74.6170.2000111.8L106 E107 D108 G112 L113 E114 A172 K173 F176L106-L110 WeakPolarHBondContact O-CB 3.32Å; L106-L110 WeakPolarHBondContact O-CG 3.21Å; L106-L110 PolarHBondContact O-N 2.93Å; E107-L110 PolarHBondContact O-N 2.96Å; D108-L110 PolarHBondContact O-N 2.9Å; L110-G112 VanDerWaalsContact C-N 3.32Å; L110-G112 PolarHBondContact O-N 3.27Å; L110-L113 PolarHBondContact O-N 3.39Å; L110-E114 WeakPolarHBondContact O-CG 3.35Å; L110-E114 PolarHBondContact O-N 3.34Å; L110-A172 HydrophobicContact CD2-CB 3.89Å; L110-K173 HydrophobicContact CD2-CG 4.2Å; L110-F176 HydrophobicContact CD2-CB 4.25Å
111G97.3Very high96.6Very high31 Ų3143.6 Ų43.632%0.3224%0.237SC..Hα-helixtrans-58.9-44.717300000111.9E107 D108 L113 E114 E115E107-G111 PolarHBondContact O-N 2.96Å; D108-G111 PolarHBondContact O-N 3.18Å; G111-L113 PolarHBondContact O-N 3.45Å; G111-E114 WeakPolarHBondContact O-CB 3.33Å; G111-E114 PolarHBondContact O-N 2.95Å; G111-E115 PolarHBondContact O-N 3.32Å; G111-E115 VanDerWaalsContact O-N 3.16Å
112G96.9Very high96.7Very high2 Ų240.9 Ų40.92%0.02122%0.221CC..Hα-helixtrans-60.8-39.1173.600000114.8W44 D108 T109 L110 E114 E115 L116W44-G112 PolarHBondContact NE1-O 3.49Å; D108-G112 PolarHBondContact O-N 2.84Å; T109-G112 PolarHBondContact O-N 2.98Å; L110-G112 VanDerWaalsContact C-N 3.32Å; L110-G112 PolarHBondContact O-N 3.27Å; G112-E114 VanDerWaalsContact C-N 3.34Å; G112-E115 PolarHBondContact O-N 3.32Å; G112-L116 PolarHBondContact O-N 3.41Å; G112-L116 VanDerWaalsContact O-N 3.13Å
113L96.9Very high96.6Very high5 Ų541 Ų413%0.02622%0.222CC..Hα-helixtrans-72.5-27.7176.9-64.8178.5000112.2W44 T109 L110 G111 L116 N117 A172 F176 Y193W44-L113 HydrophobicContact CZ2-CD2 4.43Å; T109-L113 HydrophobicContact CG2-CD1 4.08Å; T109-L113 HydrophobicContact CG2-CG 4.35Å; T109-L113 VanDerWaalsContact O-CG 3.32Å; T109-L113 WeakPolarHBondContact O-CG 3.48Å; T109-L113 PolarHBondContact O-N 3.37Å; L110-L113 PolarHBondContact O-N 3.39Å; G111-L113 PolarHBondContact O-N 3.45Å; L113-L116 HydrophobicContact CD2-CD2 4.3Å; L113-L116 PolarHBondContact O-N 3.28Å; L113-N117 WeakPolarHBondContact O-CB 3.42Å; L113-N117 PolarHBondContact O-N 3.1Å; L113-N117 PolarHBondContact O-ND2 3.03Å; L113-A172 HydrophobicContact CD1-CB 3.87Å; L113-F176 HydrophobicContact CD1-CD2 4.14Å; L113-F176 HydrophobicContact CD1-CE2 3.87Å; L113-F176 HydrophobicContact CD1-CZ 4.45Å; L113-Y193 HydrophobicContact CD1-CD2 4.06Å; L113-Y193 HydrophobicContact CD1-CE2 4.08Å; L113-Y193 HydrophobicContact CD2-CD2 3.7Å; L113-Y193 HydrophobicContact CD2-CE2 4.37Å
114E95.7Very high96.6Very high94 Ų9439.7 Ų39.744%0.43921%0.21SC..Hα-helixtrans-66.9-40.1171.5-74.2-178.717100112L110 G111 G112 N117 T118 K173L110-E114 WeakPolarHBondContact O-CG 3.35Å; L110-E114 PolarHBondContact O-N 3.34Å; G111-E114 WeakPolarHBondContact O-CB 3.33Å; G111-E114 PolarHBondContact O-N 2.95Å; G112-E114 VanDerWaalsContact C-N 3.34Å; E114-N117 PolarHBondContact O-N 3.05Å; E114-T118 PolarHBondContact O-N 3.38Å; E114-T118 PolarHBondContact O-OG1 3.49Å; E114-K173 WeakPolarHBondContact OE1-CE 3.49Å; E114-K173 IonicContact OE1-NZ 3.18Å; E114-K173 PolarHBondContact OE1-NZ 3.3Å
115E93.9Very high96.5Very high102 Ų10236.9 Ų36.948%0.47720%0.196SC..Hα-helixtrans-60.5-47.6171.4-68.5172.3-176.500111.4G111 G112 N117 T118 F119G111-E115 PolarHBondContact O-N 3.32Å; G111-E115 VanDerWaalsContact O-N 3.16Å; G112-E115 PolarHBondContact O-N 3.32Å; E115-N117 VanDerWaalsContact C-N 3.29Å; E115-N117 PolarHBondContact O-N 3.39Å; E115-T118 WeakPolarHBondContact O-CB 3.3Å; E115-T118 PolarHBondContact O-N 3.47Å; E115-F119 PolarHBondContact O-N 3.49Å
116L95.9Very high96.4Very high1 Ų136.6 Ų36.61%0.00519%0.194CC..Hα-helixtrans-59.7-39176.2179.167.2000111.9F37 W44 G112 L113 T118 F119 L120 F168 A197F37-L116 HydrophobicContact CE1-CD1 3.84Å; F37-L116 HydrophobicContact CE2-CB 4.48Å; F37-L116 HydrophobicContact CE2-CD1 4.28Å; F37-L116 HydrophobicContact CZ-CB 4.37Å; F37-L116 HydrophobicContact CZ-CD1 3.49Å; F37-L116 VanDerWaalsContact CZ-CD1 3.49Å; W44-L116 HydrophobicContact CH2-CD2 3.99Å; W44-L116 HydrophobicContact CZ2-CB 3.9Å; W44-L116 HydrophobicContact CZ2-CD1 4.39Å; W44-L116 HydrophobicContact CZ2-CD2 3.77Å; W44-L116 HydrophobicContact CZ2-CG 4.23Å; G112-L116 PolarHBondContact O-N 3.41Å; G112-L116 VanDerWaalsContact O-N 3.13Å; L113-L116 HydrophobicContact CD2-CD2 4.3Å; L113-L116 PolarHBondContact O-N 3.28Å; L116-T118 VanDerWaalsContact C-N 3.28Å; L116-T118 PolarHBondContact O-N 3.47Å; L116-F119 HydrophobicContact CD1-CD1 3.83Å; L116-F119 HydrophobicContact CD1-CE1 4.46Å; L116-F119 WeakPolarHBondContact O-CB 3.35Å; L116-F119 PolarHBondContact O-N 2.95Å; L116-L120 HydrophobicContact CD1-CD1 4.49Å; L116-L120 HydrophobicContact CD1-CG 4.26Å; L116-L120 HydrophobicContact CD2-CD1 4.23Å; L116-L120 HydrophobicContact CG-CD1 3.89Å; L116-L120 HydrophobicContact CG-CG 4.1Å; L116-L120 WeakPolarHBondContact O-CG 3.36Å; L116-L120 PolarHBondContact O-N 3.35Å; L116-F168 HydrophobicContact CD2-CD1 3.72Å; L116-F168 HydrophobicContact CD2-CE1 3.46Å; L116-F168 VanDerWaalsContact CD2-CE1 3.46Å; L116-F168 HydrophobicContact CD2-CZ 4.12Å; L116-A197 HydrophobicContact CD1-CB 4.2Å
117N95.7Very high96.2Very high78 Ų7836.4 Ų36.442%0.41719%0.193SC..Hα-helixtrans-62.9-34.2179.5-76.2-27.6000112.8L113 E114 E115 F119 L120 D121L113-N117 WeakPolarHBondContact O-CB 3.42Å; L113-N117 PolarHBondContact O-N 3.1Å; L113-N117 PolarHBondContact O-ND2 3.03Å; E114-N117 PolarHBondContact O-N 3.05Å; E115-N117 VanDerWaalsContact C-N 3.29Å; E115-N117 PolarHBondContact O-N 3.39Å; N117-F119 VanDerWaalsContact C-N 3.33Å; N117-L120 PolarHBondContact O-N 3.35Å; N117-D121 WeakPolarHBondContact O-CB 3.36Å; N117-D121 PolarHBondContact O-N 3.25Å
118T95.6Very high96Very high86 Ų8629.8 Ų29.853%0.52816%0.162SC..Hα-helixtrans-63.5-43175.6-57.10000110.8T33 E114 E115 L116 A122T33-T118 HydrophobicContact CG2-CG2 3.91Å; E114-T118 PolarHBondContact O-N 3.38Å; E114-T118 PolarHBondContact O-OG1 3.49Å; E115-T118 WeakPolarHBondContact O-CB 3.3Å; E115-T118 PolarHBondContact O-N 3.47Å; L116-T118 VanDerWaalsContact C-N 3.28Å; L116-T118 PolarHBondContact O-N 3.47Å; T118-A122 PolarHBondContact O-N 3.27Å
119F95.4Very high95.9Very high1 Ų125.7 Ų25.70%0.00414%0.14CC..Hα-helixtrans-61.7-50.3172.6162.3-98.2000112.2V34 F37 Y38 E115 L116 N117 D121 A122 V123 I200V34-F119 HydrophobicContact CB-CD2 4.46Å; V34-F119 HydrophobicContact CB-CE2 4.35Å; V34-F119 HydrophobicContact CG1-CE2 4.03Å; V34-F119 HydrophobicContact CG2-CD2 4.16Å; V34-F119 HydrophobicContact CG2-CE2 4.14Å; F37-F119 HydrophobicContact CB-CB 3.85Å; F37-F119 HydrophobicContact CB-CD2 3.56Å; F37-F119 HydrophobicContact CB-CE2 4.42Å; F37-F119 HydrophobicContact CB-CG 3.95Å; F37-F119 HydrophobicContact CD1-CB 3.88Å; F37-F119 AromaticContact CD1-CD1 3.84Å; F37-F119 HydrophobicContact CD1-CD1 3.84Å; F37-F119 AromaticContact CD1-CD2 3.48Å; F37-F119 HydrophobicContact CD1-CD2 3.48Å; F37-F119 VanDerWaalsContact CD1-CD2 3.48Å; F37-F119 HydrophobicContact CD1-CE1 4.26Å; F37-F119 AromaticContact CD1-CE2 3.92Å; F37-F119 HydrophobicContact CD1-CE2 3.92Å; F37-F119 AromaticContact CD1-CG 3.44Å; F37-F119 HydrophobicContact CD1-CG 3.44Å; F37-F119 VanDerWaalsContact CD1-CG 3.44Å; F37-F119 HydrophobicContact CD1-CZ 4.3Å; F37-F119 HydrophobicContact CD2-CB 3.82Å; F37-F119 HydrophobicContact CD2-CG 4.32Å; F37-F119 HydrophobicContact CE1-CB 4.41Å; F37-F119 AromaticContact CE1-CD1 3.96Å; F37-F119 HydrophobicContact CE1-CD1 3.96Å; F37-F119 HydrophobicContact CE1-CD2 4.4Å; F37-F119 HydrophobicContact CE1-CE1 4.35Å; F37-F119 AromaticContact CE1-CG 3.99Å; F37-F119 HydrophobicContact CE1-CG 3.99Å; F37-F119 HydrophobicContact CE2-CB 4.38Å; F37-F119 HydrophobicContact CG-CB 3.55Å; F37-F119 HydrophobicContact CG-CD1 4.41Å; F37-F119 AromaticContact CG-CD2 3.68Å; F37-F119 HydrophobicContact CG-CD2 3.68Å; F37-F119 AromaticContact CG-CG 3.62Å; F37-F119 HydrophobicContact CG-CG 3.62Å; Y38-F119 HydrophobicContact CD1-CE2 4.45Å; Y38-F119 AromaticContact CE1-CE2 3.61Å; Y38-F119 HydrophobicContact CE1-CE2 3.61Å; Y38-F119 AromaticContact CE1-CZ 3.83Å; Y38-F119 HydrophobicContact CE1-CZ 3.83Å; Y38-F119 AromaticContact CZ-CE2 3.72Å; Y38-F119 WeakPolarHBondContact OH-CE2 3.34Å; E115-F119 PolarHBondContact O-N 3.49Å; L116-F119 HydrophobicContact CD1-CD1 3.83Å; L116-F119 HydrophobicContact CD1-CE1 4.46Å; L116-F119 WeakPolarHBondContact O-CB 3.35Å; L116-F119 PolarHBondContact O-N 2.95Å; N117-F119 VanDerWaalsContact C-N 3.33Å; F119-D121 VanDerWaalsContact C-N 3.33Å; F119-D121 PolarHBondContact O-N 3.26Å; F119-A122 WeakPolarHBondContact O-CB 3.43Å; F119-A122 PolarHBondContact O-N 2.97Å; F119-V123 HydrophobicContact CD2-CG2 4.29Å; F119-V123 HydrophobicContact CE1-CG2 4.11Å; F119-V123 HydrophobicContact CE2-CG2 3.81Å; F119-V123 HydrophobicContact CZ-CG2 3.69Å; F119-V123 WeakPolarHBondContact O-CG2 3.47Å; F119-V123 PolarHBondContact O-N 3.48Å; F119-I200 HydrophobicContact CE1-CG2 3.65Å; F119-I200 HydrophobicContact CZ-CG2 3.57Å
120L96.3Very high95.6Very high5 Ų525.8 Ų25.83%0.02614%0.141CC..Hα-helixtrans-61.8-40.3-178.5-66.4173.6000112L116 N117 A122 V123 E124 I165 F168 I200L116-L120 HydrophobicContact CD1-CD1 4.49Å; L116-L120 HydrophobicContact CD1-CG 4.26Å; L116-L120 HydrophobicContact CD2-CD1 4.23Å; L116-L120 HydrophobicContact CG-CD1 3.89Å; L116-L120 HydrophobicContact CG-CG 4.1Å; L116-L120 WeakPolarHBondContact O-CG 3.36Å; L116-L120 PolarHBondContact O-N 3.35Å; N117-L120 PolarHBondContact O-N 3.35Å; L120-A122 PolarHBondContact O-N 3.26Å; L120-V123 PolarHBondContact O-N 3.23Å; L120-E124 WeakPolarHBondContact O-CG 3.41Å; L120-E124 PolarHBondContact O-N 3.29Å; L120-I165 HydrophobicContact CB-CG2 4.37Å; L120-I165 HydrophobicContact CD2-CG1 4.16Å; L120-I165 HydrophobicContact CD2-CG2 4.38Å; L120-F168 HydrophobicContact CD1-CB 3.51Å; L120-F168 HydrophobicContact CD1-CD1 4.12Å; L120-F168 HydrophobicContact CD1-CD2 3.67Å; L120-F168 HydrophobicContact CD1-CE2 4.4Å; L120-F168 HydrophobicContact CD1-CG 3.5Å; L120-F168 VanDerWaalsContact CD1-CG 3.5Å; L120-F168 HydrophobicContact CD2-CD2 4.07Å; L120-F168 HydrophobicContact CD2-CE2 4.26Å; L120-I200 HydrophobicContact CD2-CD1 4.14Å
121D96.8Very high95.2Very high50 Ų5026.1 Ų26.127%0.26714%0.143SC..Hα-helixtrans-64.3-39176.8-178.669.2000112.2N117 F119 E124 K125 R252N117-D121 WeakPolarHBondContact O-CB 3.36Å; N117-D121 PolarHBondContact O-N 3.25Å; F119-D121 VanDerWaalsContact C-N 3.33Å; F119-D121 PolarHBondContact O-N 3.26Å; D121-E124 PolarHBondContact O-N 3.03Å; D121-K125 WeakPolarHBondContact O-CG 3.47Å; D121-K125 PolarHBondContact O-N 3.48Å; D121-K125 IonicContact OD1-NZ 2.75Å; D121-K125 WeakPolarHBondContact OD2-CE 3.47Å; D121-K125 IonicContact OD2-NZ 2.72Å; D121-K125 PolarHBondContact OD2-NZ 2.94Å; D121-R252 IonicContact OD1-CZ 2.75Å; D121-R252 IonicContact OD1-NH1 2.62Å; D121-R252 PolarHBondContact OD1-NH1 3.23Å; D121-R252 IonicContact OD1-NH2 2.8Å; D121-R252 PolarHBondContact OD1-NH2 2.93Å
122A96.4Very high94.7Very high3 Ų327.5 Ų27.53%0.02514%0.141CC..Hα-helixtrans-63.3-43.5172.600000111.7Y30 T33 V34 T118 F119 L120 E124 K125 L126Y30-A122 HydrophobicContact CD1-CB 4.45Å; T33-A122 HydrophobicContact CG2-CB 3.87Å; V34-A122 HydrophobicContact CG2-CB 3.95Å; T118-A122 PolarHBondContact O-N 3.27Å; F119-A122 WeakPolarHBondContact O-CB 3.43Å; F119-A122 PolarHBondContact O-N 2.97Å; L120-A122 PolarHBondContact O-N 3.26Å; A122-E124 PolarHBondContact O-N 2.82Å; A122-K125 PolarHBondContact O-N 2.94Å; A122-L126 WeakPolarHBondContact O-CB 3.37Å; A122-L126 VanDerWaalsContact O-CG 3.3Å; A122-L126 WeakPolarHBondContact O-CG 3.34Å; A122-L126 PolarHBondContact O-N 3.14Å
123V95.6Very high94.3Very high1 Ų127.4 Ų27.41%0.00614%0.14CC..Hα-helixtrans-60.9-44174.7176.30000111.1V34 F119 L120 K125 L126 A127 A158 I161 I165V34-V123 HydrophobicContact CG2-CG2 3.73Å; F119-V123 HydrophobicContact CD2-CG2 4.29Å; F119-V123 HydrophobicContact CE1-CG2 4.11Å; F119-V123 HydrophobicContact CE2-CG2 3.81Å; F119-V123 HydrophobicContact CZ-CG2 3.69Å; F119-V123 WeakPolarHBondContact O-CG2 3.47Å; F119-V123 PolarHBondContact O-N 3.48Å; L120-V123 PolarHBondContact O-N 3.23Å; V123-K125 PolarHBondContact O-N 3.19Å; V123-L126 PolarHBondContact O-N 3.04Å; V123-A127 WeakPolarHBondContact O-CB 3.49Å; V123-A127 PolarHBondContact O-N 3.35Å; V123-A158 HydrophobicContact CG1-CB 4.06Å; V123-I161 HydrophobicContact CG1-CD1 3.56Å; V123-I161 HydrophobicContact CG1-CG1 3.87Å; V123-I161 HydrophobicContact CG2-CD1 4.37Å; V123-I165 HydrophobicContact CB-CD1 4.16Å; V123-I165 HydrophobicContact CG1-CD1 3.77Å
124E96.1Very high94Very high10 Ų1027.2 Ų27.25%0.04714%0.139CC..Hα-helixtrans-60.7-44.2177.7-71.6178.5-146.500111.9L120 D121 A122 L126 A127 V128 I165 K169 R252 L256L120-E124 WeakPolarHBondContact O-CG 3.41Å; L120-E124 PolarHBondContact O-N 3.29Å; D121-E124 PolarHBondContact O-N 3.03Å; A122-E124 PolarHBondContact O-N 2.82Å; E124-L126 VanDerWaalsContact C-N 3.35Å; E124-A127 WeakPolarHBondContact O-CB 3.32Å; E124-A127 PolarHBondContact O-N 3.2Å; E124-V128 WeakPolarHBondContact O-CG2 3.44Å; E124-V128 PolarHBondContact O-N 3.14Å; E124-I165 HydrophobicContact CG-CD1 3.61Å; E124-I165 HydrophobicContact CG-CG2 4.22Å; E124-I165 VanDerWaalsContact OE1-CG2 3.23Å; E124-I165 WeakPolarHBondContact OE1-CG2 3.36Å; E124-K169 WeakPolarHBondContact OE1-CE 3.22Å; E124-K169 IonicContact OE1-NZ 3.4Å; E124-K169 PolarHBondContact OE1-NZ 3.1Å; E124-K169 IonicContact OE2-NZ 3.73Å; E124-K169 PolarHBondContact OE2-NZ 3.47Å; E124-R252 IonicContact OE2-CZ 3.33Å; E124-R252 IonicContact OE2-NH1 4Å; E124-R252 PolarHBondContact OE2-NH1 3.46Å; E124-L256 HydrophobicContact CG-CD2 4.19Å
125K97.1Very high93.4Very high34 Ų3426 Ų2615%0.14814%0.137CC..Hα-helixtrans-65.4-36.6177-71.8171177.8159.40112.5Y30 D121 A122 V123 V128 T129 R246Y30-K125 HydrophobicContact CD1-CD 4.13Å; Y30-K125 HydrophobicContact CD2-CB 3.91Å; Y30-K125 HydrophobicContact CD2-CD 4.49Å; Y30-K125 HydrophobicContact CE1-CD 3.62Å; Y30-K125 HydrophobicContact CE2-CB 3.95Å; Y30-K125 HydrophobicContact CE2-CD 4.02Å; Y30-K125 HydrophobicContact CG-CB 4.3Å; D121-K125 WeakPolarHBondContact O-CG 3.47Å; D121-K125 PolarHBondContact O-N 3.48Å; D121-K125 IonicContact OD1-NZ 2.75Å; D121-K125 WeakPolarHBondContact OD2-CE 3.47Å; D121-K125 IonicContact OD2-NZ 2.72Å; D121-K125 PolarHBondContact OD2-NZ 2.94Å; A122-K125 PolarHBondContact O-N 2.94Å; V123-K125 PolarHBondContact O-N 3.19Å; K125-V128 WeakPolarHBondContact O-CG2 3.03Å; K125-T129 PolarHBondContact O-N 3.28Å; K125-T129 PolarHBondContact O-OG1 2.72Å; K125-R246 HydrophobicContact CB-CG 4.13Å; K125-R246 HydrophobicContact CG-CG 4.34Å
126L95.4Very high92.5Very high0 Ų029.2 Ų29.20%015%0.153CC..Hα-helixtrans-67.3-41.6173-73.6166.1000111.5T27 M31 V34 A122 V123 E124 V128 T129 V154 I155 A158T27-L126 HydrophobicContact CG2-CD2 3.92Å; M31-L126 HydrophobicContact CG-CD1 4.42Å; M31-L126 HydrophobicContact CG-CD2 3.85Å; V34-L126 HydrophobicContact CG2-CD1 3.81Å; A122-L126 WeakPolarHBondContact O-CB 3.37Å; A122-L126 VanDerWaalsContact O-CG 3.3Å; A122-L126 WeakPolarHBondContact O-CG 3.34Å; A122-L126 PolarHBondContact O-N 3.14Å; V123-L126 PolarHBondContact O-N 3.04Å; E124-L126 VanDerWaalsContact C-N 3.35Å; L126-V128 PolarHBondContact O-N 3.32Å; L126-T129 VanDerWaalsContact O-CB 3.24Å; L126-T129 WeakPolarHBondContact O-CB 3.47Å; L126-T129 PolarHBondContact O-N 3.39Å; L126-V154 HydrophobicContact CD1-CG1 3.86Å; L126-V154 HydrophobicContact CD2-CG1 4.42Å; L126-I155 HydrophobicContact CD2-CG1 4.46Å; L126-A158 HydrophobicContact CB-CB 3.71Å
127A93.6Very high91.6Very high0 Ų030.7 Ų30.70%016%0.161CC..Hα-helixtrans-58.7-38.7-179.700000111.8V123 E124 T129 A158 Q159 C162 F255V123-A127 WeakPolarHBondContact O-CB 3.49Å; V123-A127 PolarHBondContact O-N 3.35Å; E124-A127 WeakPolarHBondContact O-CB 3.32Å; E124-A127 PolarHBondContact O-N 3.2Å; A127-T129 VanDerWaalsContact C-N 3.32Å; A127-T129 PolarHBondContact O-N 2.87Å; A127-A158 HydrophobicContact CB-CB 4.21Å; A127-Q159 HydrophobicContact CB-CG 4.39Å; A127-Q159 WeakPolarHBondContact O-CG 3.31Å; A127-Q159 PolarHBondContact O-NE2 3.38Å; A127-C162 HydrophobicContact CB-CB 3.88Å; A127-F255 HydrophobicContact CB-CD1 4.1Å; A127-F255 HydrophobicContact CB-CE1 3.84Å; A127-F255 WeakPolarHBondContact O-CE1 3.45Å; A127-F255 WeakPolarHBondContact O-CZ 3.23Å
128V93.2Very high90.7Very high0 Ų034.1 Ų34.10%017%0.174CC..THydrogen-bonded Turntrans-89.611.6177.1-60.50000114.2E124 K125 L126 R246 F251 R252 F255 L515E124-V128 WeakPolarHBondContact O-CG2 3.44Å; E124-V128 PolarHBondContact O-N 3.14Å; K125-V128 WeakPolarHBondContact O-CG2 3.03Å; L126-V128 PolarHBondContact O-N 3.32Å; V128-R246 HydrophobicContact CG2-CB 4.21Å; V128-R246 HydrophobicContact CG2-CG 4.14Å; V128-F251 HydrophobicContact CB-CD1 4.23Å; V128-F251 HydrophobicContact CB-CE1 3.74Å; V128-F251 HydrophobicContact CG1-CD1 3.85Å; V128-F251 HydrophobicContact CG1-CE1 3.42Å; V128-F251 VanDerWaalsContact CG1-CE1 3.42Å; V128-F251 HydrophobicContact CG1-CZ 4.39Å; V128-R252 HydrophobicContact CG1-CG 4.09Å; V128-R252 HydrophobicContact CG2-CG 3.96Å; V128-F255 HydrophobicContact CG1-CB 3.78Å; V128-F255 HydrophobicContact CG1-CD1 3.67Å; V128-F255 HydrophobicContact CG1-CD2 4.11Å; V128-F255 HydrophobicContact CG1-CE1 4.24Å; V128-F255 HydrophobicContact CG1-CG 3.58Å; V128-L515 WeakPolarHBondContact O-CD2 3.25Å
129T94.3Very high90.1Very high0 Ų030.5 Ų30.50%015%0.152CC..SBendtrans-82.6139175.6-69.90000111Y23 T27 K125 L126 A127 L131 F134 I155 R246Y23-T129 HydrophobicContact CE1-CG2 4.38Å; T27-T129 HydrophobicContact CG2-CG2 4.23Å; K125-T129 PolarHBondContact O-N 3.28Å; K125-T129 PolarHBondContact O-OG1 2.72Å; L126-T129 VanDerWaalsContact O-CB 3.24Å; L126-T129 WeakPolarHBondContact O-CB 3.47Å; L126-T129 PolarHBondContact O-N 3.39Å; A127-T129 VanDerWaalsContact C-N 3.32Å; A127-T129 PolarHBondContact O-N 2.87Å; T129-L131 PolarHBondContact O-N 2.77Å; T129-F134 HydrophobicContact CG2-CD2 4.29Å; T129-F134 HydrophobicContact CG2-CE2 3.74Å; T129-I155 HydrophobicContact CG2-CD1 3.62Å; T129-I155 HydrophobicContact CG2-CG1 4.11Å; T129-I155 WeakPolarHBondContact O-CG2 3.23Å; T129-R246 PolarHBondContact OG1-NE 3.41Å; T129-R246 VanDerWaalsContact OG1-NE 3.11Å; T129-R246 PolarHBondContact OG1-NH2 3Å
130S91.5Very high89.7Confident1 Ų130.6 Ų30.61%0.00715%0.152CC..  trans-75121.9179.2-179.80000111.2Y23 H132 V133 L515Y23-S130 PolarHBondContact OH-N 3.05Å; S130-H132 PolarHBondContact O-N 3.29Å; S130-H132 PolarHBondContact OG-N 3.36Å; S130-V133 PolarHBondContact O-N 2.82Å; S130-L515 PolarHBondContact OG-O 3.38Å
131L90.2Very high89.2Confident44 Ų4436.1 Ų36.123%0.2317%0.173CC..G310 helixtrans-61.2-27.7171.3-69.8168.3000112.5T129 V133 F134 T135 Q152 I155T129-L131 PolarHBondContact O-N 2.77Å; L131-V133 VanDerWaalsContact C-N 3.3Å; L131-V133 PolarHBondContact O-N 3.28Å; L131-F134 CarbonylContact O-C 3.56Å; L131-F134 PolarHBondContact O-N 3.5Å; L131-T135 PolarHBondContact O-N 2.73Å; L131-T135 PolarHBondContact O-OG1 3.29Å; L131-Q152 HydrophobicContact CD2-CB 4.02Å; L131-Q152 HydrophobicContact CD2-CG 4.07Å; L131-I155 HydrophobicContact CD2-CB 3.65Å; L131-I155 HydrophobicContact CD2-CD1 4.26Å; L131-I155 HydrophobicContact CD2-CG2 3.44Å; L131-I155 VanDerWaalsContact CD2-CG2 3.44Å; L131-I155 HydrophobicContact CG-CG2 3.82Å
132H86.5Confident88.7Confident61 Ų6135 Ų3528%0.28217%0.167SC..G310 helixtrans-69-27.4-175.1-6786.4000113.2S130 F134 T135 L515 Q516 F519S130-H132 PolarHBondContact O-N 3.29Å; S130-H132 PolarHBondContact OG-N 3.36Å; H132-F134 PolarHBondContact O-N 3.24Å; H132-T135 PolarHBondContact O-N 3.08Å; H132-L515 PolarHBondContact ND1-O 3.23Å; H132-Q516 VanDerWaalsContact CE1-C 3.49Å; H132-Q516 WeakPolarHBondContact CE1-CA 3.42Å; H132-Q516 PolarHBondContact CE1-O 2.96Å; H132-Q516 PolarHBondContact NE2-O 3.3Å; H132-F519 HydrophobicContact CB-CB 4.38Å; H132-F519 WeakPolarHBondContact O-CB 2.95Å
133V88.9Confident88.2Confident0 Ų035 Ų350%017%0.167CC..G310 helixtrans-67.1-29.8173.2178.60000110.9L20 Y23 S130 L131 N137 I140 I239 L242 F519L20-V133 HydrophobicContact CD1-CG1 3.89Å; Y23-V133 HydrophobicContact CD1-CG1 3.99Å; Y23-V133 HydrophobicContact CD1-CG2 4.48Å; Y23-V133 HydrophobicContact CE1-CB 4.11Å; Y23-V133 HydrophobicContact CE1-CG1 4.01Å; Y23-V133 HydrophobicContact CE1-CG2 3.89Å; S130-V133 PolarHBondContact O-N 2.82Å; L131-V133 VanDerWaalsContact C-N 3.3Å; L131-V133 PolarHBondContact O-N 3.28Å; V133-N137 PolarHBondContact O-ND2 3.2Å; V133-I140 HydrophobicContact CG1-CD1 3.94Å; V133-I140 WeakPolarHBondContact O-CD1 3.48Å; V133-I239 HydrophobicContact CG1-CD1 4.27Å; V133-I239 HydrophobicContact CG2-CD1 3.72Å; V133-L242 HydrophobicContact CG2-CD1 3.76Å; V133-F519 HydrophobicContact CG2-CD2 4.07Å; V133-F519 HydrophobicContact CG2-CE2 4.33Å; V133-F519 HydrophobicContact CG2-CG 4.47Å
134F89.2Confident87.5Confident0 Ų044.2 Ų44.20%021%0.21CC..G310 helixtrans-103.316.7-177.5-61.1-76.7000112.9Y23 V24 T27 T129 L131 H132 F148 V151 Q152 I155Y23-F134 HydrophobicContact CE1-CE2 4.18Å; V24-F134 HydrophobicContact CB-CE1 4.4Å; V24-F134 HydrophobicContact CG1-CE1 4.09Å; V24-F134 HydrophobicContact CG2-CE1 3.99Å; V24-F134 HydrophobicContact CG2-CZ 4.16Å; T27-F134 HydrophobicContact CG2-CE1 4.47Å; T27-F134 HydrophobicContact CG2-CE2 3.88Å; T27-F134 HydrophobicContact CG2-CZ 3.7Å; T27-F134 WeakPolarHBondContact OG1-CZ 3.23Å; T129-F134 HydrophobicContact CG2-CD2 4.29Å; T129-F134 HydrophobicContact CG2-CE2 3.74Å; L131-F134 CarbonylContact O-C 3.56Å; L131-F134 PolarHBondContact O-N 3.5Å; H132-F134 PolarHBondContact O-N 3.24Å; F134-F148 HydrophobicContact CB-CD1 4.23Å; F134-F148 HydrophobicContact CD1-CD1 4.49Å; F134-F148 WeakPolarHBondContact O-CB 3.46Å; F134-F148 WeakPolarHBondContact O-CD1 3.43Å; F134-V151 HydrophobicContact CB-CB 4.44Å; F134-V151 HydrophobicContact CB-CG1 4.08Å; F134-V151 HydrophobicContact CD1-CB 4.11Å; F134-V151 HydrophobicContact CD1-CG1 3.46Å; F134-V151 VanDerWaalsContact CD1-CG1 3.46Å; F134-V151 HydrophobicContact CD1-CG2 4.39Å; F134-V151 HydrophobicContact CD2-CG1 3.91Å; F134-V151 HydrophobicContact CE1-CG1 3.8Å; F134-V151 HydrophobicContact CE2-CG1 4.23Å; F134-V151 HydrophobicContact CG-CB 4.29Å; F134-V151 HydrophobicContact CG-CG1 3.51Å; F134-V151 HydrophobicContact CZ-CG1 4.19Å; F134-Q152 HydrophobicContact CB-CG 4.18Å; F134-Q152 PolarHBondContact O-NE2 3.27Å; F134-I155 HydrophobicContact CD2-CD1 3.63Å; F134-I155 HydrophobicContact CE2-CD1 4.07Å; F134-I155 HydrophobicContact CG-CD1 4.36Å
135T84.9Confident86.9Confident68 Ų6849.5 Ų49.542%0.41723%0.233SC..SBendtrans-77.3136167-53.40000108.8L131 H132 N137L131-T135 PolarHBondContact O-N 2.73Å; L131-T135 PolarHBondContact O-OG1 3.29Å; H132-T135 PolarHBondContact O-N 3.08Å; T135-N137 PolarHBondContact O-N 2.88Å; T135-N137 VanDerWaalsContact O-N 3.13Å; T135-N137 PolarHBondContact O-ND2 3.49Å
136E73.8Confident86.4Confident170 Ų17048.2 Ų48.279%0.79423%0.227SC*.SBendtrans-48.1121.6-177.2-169.4177.4-169.600110.7F148E136-F148 HydrophobicContact CB-CD2 4.42Å; E136-F148 HydrophobicContact CG-CD2 4.37Å
137N77.3Confident86Confident32 Ų3250.5 Ų50.517%0.17124%0.244CC..  trans-148.2166.1-174.766.869.4000111V133 T135 I139 I140V133-N137 PolarHBondContact O-ND2 3.2Å; T135-N137 PolarHBondContact O-N 2.88Å; T135-N137 VanDerWaalsContact O-N 3.13Å; T135-N137 PolarHBondContact O-ND2 3.49Å; N137-I139 VanDerWaalsContact C-N 3.3Å; N137-I139 WeakPolarHBondContact OD1-CA 3.24Å; N137-I139 WeakPolarHBondContact OD1-CB 2.88Å; N137-I139 PolarHBondContact OD1-N 3.2Å; N137-I140 PolarHBondContact OD1-N 2.91Å
138Q76Confident85.7Confident151 Ų15152 Ų5271%0.70625%0.25SC*.SBendtrans-87.21.8-179.9-63-178.4-400113.4
139I83Confident85.5Confident10 Ų1057.5 Ų57.55%0.05128%0.28CS..SBendtrans-96.5-40-170.8-63.7174.9000110.9L20 N137 V222 N223 L227 M235 L520L20-I139 HydrophobicContact CD2-CG2 3.78Å; N137-I139 VanDerWaalsContact C-N 3.3Å; N137-I139 WeakPolarHBondContact OD1-CA 3.24Å; N137-I139 WeakPolarHBondContact OD1-CB 2.88Å; N137-I139 PolarHBondContact OD1-N 3.2Å; I139-V222 HydrophobicContact CG2-CG1 3.96Å; I139-V222 CarbonylContact O-C 3.55Å; I139-V222 WeakPolarHBondContact O-CA 3.41Å; I139-N223 WeakPolarHBondContact CA-O 3.24Å; I139-N223 WeakPolarHBondContact CG2-O 3.17Å; I139-N223 PolarHBondContact O-N 2.97Å; I139-L227 HydrophobicContact CD1-CD1 3.99Å; I139-L227 HydrophobicContact CD1-CD2 4.17Å; I139-L227 HydrophobicContact CG1-CD1 4.44Å; I139-M235 HydrophobicContact CD1-CE 3.41Å; I139-M235 VanDerWaalsContact CD1-CE 3.41Å; I139-M235 HydrophobicContact CD1-SD 4.15Å; I139-L520 HydrophobicContact CD1-CD1 3.74Å; I139-L520 HydrophobicContact CD1-CD2 4.04Å; I139-L520 HydrophobicContact CD1-CG 4.2Å
140I86.9Confident85.2Confident2 Ų259.8 Ų59.81%0.0129%0.292CS..EExtended strand (participates in β ladder)trans-109.4132.2-175.3-56.3170.8000109.2L20 V24 V133 N137 L142 F148 F519L20-I140 HydrophobicContact CD1-CD1 3.83Å; L20-I140 HydrophobicContact CD1-CG1 4.47Å; L20-I140 HydrophobicContact CD2-CD1 3.89Å; L20-I140 HydrophobicContact CD2-CG1 3.65Å; L20-I140 HydrophobicContact CG-CD1 4.01Å; L20-I140 HydrophobicContact CG-CG1 4.11Å; V24-I140 HydrophobicContact CG2-CD1 4.09Å; V24-I140 HydrophobicContact CG2-CG2 4.26Å; V133-I140 HydrophobicContact CG1-CD1 3.94Å; V133-I140 WeakPolarHBondContact O-CD1 3.48Å; N137-I140 PolarHBondContact OD1-N 2.91Å; I140-L142 HydrophobicContact CG2-CD2 4.05Å; I140-L142 HydrophobicContact CG2-CG 4.49Å; I140-F148 HydrophobicContact CB-CE1 4.41Å; I140-F148 HydrophobicContact CB-CZ 4.13Å; I140-F148 HydrophobicContact CG2-CE1 4.42Å; I140-F148 HydrophobicContact CG2-CZ 4.33Å; I140-F148 WeakPolarHBondContact O-CZ 3.04Å; I140-F519 HydrophobicContact CD1-CE1 4.49Å
141Y87Confident85.1Confident121 Ų12159.8 Ų59.848%0.47529%0.292SS..EExtended strand (participates in β ladder)trans-110.6121166.9-61-84.2000108.5I220 A221 N223Y141-I220 WeakPolarHBondContact O-CA 3.43Å; Y141-A221 HydrophobicContact CD2-CB 4.22Å; Y141-A221 PolarHBondContact N-O 3.29Å; Y141-A221 PolarHBondContact O-N 3.24Å; Y141-N223 HydrophobicContact CE2-CB 3.68Å
142L86.3Confident85.1Confident26 Ų2660.1 Ų60.114%0.13629%0.292CS..  trans-87.1159.8174.5-63.9179.9000110.4V24 I140 F148 V151V24-L142 HydrophobicContact CG1-CD2 3.79Å; I140-L142 HydrophobicContact CG2-CD2 4.05Å; I140-L142 HydrophobicContact CG2-CG 4.49Å; L142-F148 HydrophobicContact CD1-CD1 3.59Å; L142-F148 HydrophobicContact CD1-CD2 4.25Å; L142-F148 HydrophobicContact CD1-CE1 3.75Å; L142-F148 HydrophobicContact CD1-CE2 4.37Å; L142-F148 HydrophobicContact CD1-CG 3.87Å; L142-F148 HydrophobicContact CD1-CZ 4.15Å; L142-F148 HydrophobicContact CG-CD1 4.33Å; L142-F148 HydrophobicContact CG-CE1 3.97Å; L142-F148 HydrophobicContact CG-CE2 4.47Å; L142-F148 HydrophobicContact CG-CZ 4.05Å; L142-V151 HydrophobicContact CD1-CG2 4.09Å
143P85.3Confident85.2Confident3 Ų359.1 Ų59.12%0.01930%0.295CS..  trans-51.7144.8170-25.935.3000111.9L28 K145 I146 M216 E219 I220L28-P143 HydrophobicContact CD1-CG 4.26Å; P143-K145 PolarHBondContact O-N 3.39Å; P143-I146 HydrophobicContact CB-CD1 4.45Å; P143-I146 HydrophobicContact CG-CD1 4.34Å; P143-I146 PolarHBondContact O-N 3.38Å; P143-I146 VanDerWaalsContact O-O 3.13Å; P143-M216 HydrophobicContact CB-CB 4.04Å; P143-M216 HydrophobicContact CB-SD 4.42Å; P143-M216 HydrophobicContact CG-CB 3.79Å; P143-M216 WeakPolarHBondContact CG-O 3.36Å; P143-E219 HydrophobicContact CB-CB 4.2Å; P143-E219 WeakPolarHBondContact CB-OE2 3.44Å; P143-E219 HydrophobicContact CG-CB 4.13Å; P143-I220 HydrophobicContact CG-CG1 4.5Å
144E81.6Confident85.3Confident196 Ų19659.2 Ų59.292%0.91630%0.295SS*.THydrogen-bonded Turntrans-56.7-25.9-173.9-74.3-172170.200113.9
145K83.5Confident85.4Confident120 Ų12059.2 Ų59.252%0.52230%0.295SS..THydrogen-bonded Turntrans-84.6-7.4-178.2-61.2-173.5-179.6-176.30114.4P143 D211 M216P143-K145 PolarHBondContact O-N 3.39Å; K145-D211 HydrophobicContact CD-CB 4.29Å; K145-D211 WeakPolarHBondContact CD-OD2 3.48Å; K145-D211 IonicContact NZ-OD2 2.91Å; K145-D211 PolarHBondContact NZ-OD2 3.03Å; K145-M216 HydrophobicContact CD-CE 3.66Å
146I85Confident85.6Confident7 Ų758.4 Ų58.44%0.03629%0.292CS..  trans-126.1118-173.9-58.4170.3000109L28 P143 V151 I212 M216L28-I146 HydrophobicContact CD1-CD1 4.17Å; L28-I146 HydrophobicContact CD2-CD1 4.26Å; L28-I146 HydrophobicContact CD2-CG2 4.32Å; P143-I146 HydrophobicContact CB-CD1 4.45Å; P143-I146 HydrophobicContact CG-CD1 4.34Å; P143-I146 PolarHBondContact O-N 3.38Å; P143-I146 VanDerWaalsContact O-O 3.13Å; I146-V151 HydrophobicContact CG2-CG2 3.72Å; I146-I212 HydrophobicContact CD1-CB 4.08Å; I146-I212 HydrophobicContact CD1-CD1 3.67Å; I146-I212 HydrophobicContact CD1-CG1 3.65Å; I146-M216 HydrophobicContact CD1-SD 3.98Å; I146-M216 HydrophobicContact CG1-SD 4.47Å
147S88.1Confident86.4Confident49 Ų4950.8 Ų50.834%0.34326%0.258SS..  trans-87.5161.4173.572.90000112D149 D150 V151S147-D149 PolarHBondContact O-N 3.34Å; S147-D149 PolarHBondContact OG-N 2.94Å; S147-D150 WeakPolarHBondContact CB-OD2 3.5Å; S147-D150 PolarHBondContact N-OD2 2.88Å; S147-D150 PolarHBondContact O-N 3.18Å; S147-D150 PolarHBondContact OG-N 3.35Å; S147-D150 VanDerWaalsContact OG-N 3.1Å; S147-D150 PolarHBondContact OG-OD2 2.58Å; S147-V151 PolarHBondContact O-N 2.88Å
148F87.8Confident87.1Confident30 Ų3049.2 Ų49.213%0.13225%0.249CC..Hα-helixtrans-59.8-35.7169.8-77.1-71.4000112F134 E136 I140 L142 D150 V151 Q152F134-F148 HydrophobicContact CB-CD1 4.23Å; F134-F148 HydrophobicContact CD1-CD1 4.49Å; F134-F148 WeakPolarHBondContact O-CB 3.46Å; F134-F148 WeakPolarHBondContact O-CD1 3.43Å; E136-F148 HydrophobicContact CB-CD2 4.42Å; E136-F148 HydrophobicContact CG-CD2 4.37Å; I140-F148 HydrophobicContact CB-CE1 4.41Å; I140-F148 HydrophobicContact CB-CZ 4.13Å; I140-F148 HydrophobicContact CG2-CE1 4.42Å; I140-F148 HydrophobicContact CG2-CZ 4.33Å; I140-F148 WeakPolarHBondContact O-CZ 3.04Å; L142-F148 HydrophobicContact CD1-CD1 3.59Å; L142-F148 HydrophobicContact CD1-CD2 4.25Å; L142-F148 HydrophobicContact CD1-CE1 3.75Å; L142-F148 HydrophobicContact CD1-CE2 4.37Å; L142-F148 HydrophobicContact CD1-CG 3.87Å; L142-F148 HydrophobicContact CD1-CZ 4.15Å; L142-F148 HydrophobicContact CG-CD1 4.33Å; L142-F148 HydrophobicContact CG-CE1 3.97Å; L142-F148 HydrophobicContact CG-CE2 4.47Å; L142-F148 HydrophobicContact CG-CZ 4.05Å; F148-D150 VanDerWaalsContact C-N 3.34Å; F148-D150 PolarHBondContact O-N 2.98Å; F148-V151 PolarHBondContact O-N 3.24Å; F148-Q152 WeakPolarHBondContact O-CG 3.47Å; F148-Q152 PolarHBondContact O-N 3.27Å
149D87.7Confident87.8Confident117 Ų11744.2 Ų44.263%0.62623%0.226SC*.Hα-helixtrans-64-39.1177.9-68.7-16.3000111.5S147 Q152 A153S147-D149 PolarHBondContact O-N 3.34Å; S147-D149 PolarHBondContact OG-N 2.94Å; D149-Q152 PolarHBondContact O-N 3.4Å; D149-A153 VanDerWaalsContact O-CB 3.28Å; D149-A153 WeakPolarHBondContact O-CB 3.41Å; D149-A153 PolarHBondContact O-N 2.62Å
150D88.1Confident87.9Confident48 Ų4847.6 Ų47.626%0.25724%0.241SC..Hα-helixtrans-62-46.3176-61.1-47.6000111.1S147 F148 A153 V154 F210S147-D150 WeakPolarHBondContact CB-OD2 3.5Å; S147-D150 PolarHBondContact N-OD2 2.88Å; S147-D150 PolarHBondContact O-N 3.18Å; S147-D150 PolarHBondContact OG-N 3.35Å; S147-D150 VanDerWaalsContact OG-N 3.1Å; S147-D150 PolarHBondContact OG-OD2 2.58Å; F148-D150 VanDerWaalsContact C-N 3.34Å; F148-D150 PolarHBondContact O-N 2.98Å; D150-A153 PolarHBondContact O-N 2.78Å; D150-V154 WeakPolarHBondContact O-CG2 3.42Å; D150-V154 PolarHBondContact O-N 3.42Å; D150-V154 VanDerWaalsContact O-N 3.13Å; D150-F210 HydrophobicContact CB-CD1 3.99Å; D150-F210 HydrophobicContact CB-CG 4.27Å
151V90.4Very high88Confident0 Ų047.5 Ų47.50%024%0.241CC..Hα-helixtrans-63.3-45.3178.6-178.30000110.9T27 L28 M31 F134 L142 I146 S147 F148 A153 V154 I155T27-V151 HydrophobicContact CG2-CG1 4.07Å; L28-V151 HydrophobicContact CD2-CG2 4Å; M31-V151 HydrophobicContact CE-CB 4.34Å; M31-V151 HydrophobicContact CE-CG2 3.94Å; M31-V151 HydrophobicContact SD-CB 4.21Å; M31-V151 HydrophobicContact SD-CG1 3.87Å; M31-V151 HydrophobicContact SD-CG2 3.99Å; F134-V151 HydrophobicContact CB-CB 4.44Å; F134-V151 HydrophobicContact CB-CG1 4.08Å; F134-V151 HydrophobicContact CD1-CB 4.11Å; F134-V151 HydrophobicContact CD1-CG1 3.46Å; F134-V151 VanDerWaalsContact CD1-CG1 3.46Å; F134-V151 HydrophobicContact CD1-CG2 4.39Å; F134-V151 HydrophobicContact CD2-CG1 3.91Å; F134-V151 HydrophobicContact CE1-CG1 3.8Å; F134-V151 HydrophobicContact CE2-CG1 4.23Å; F134-V151 HydrophobicContact CG-CB 4.29Å; F134-V151 HydrophobicContact CG-CG1 3.51Å; F134-V151 HydrophobicContact CZ-CG1 4.19Å; L142-V151 HydrophobicContact CD1-CG2 4.09Å; I146-V151 HydrophobicContact CG2-CG2 3.72Å; S147-V151 PolarHBondContact O-N 2.88Å; F148-V151 PolarHBondContact O-N 3.24Å; V151-A153 PolarHBondContact O-N 2.83Å; V151-V154 PolarHBondContact O-N 3.48Å; V151-I155 HydrophobicContact CG1-CD1 3.76Å; V151-I155 WeakPolarHBondContact O-CG1 3.32Å; V151-I155 PolarHBondContact O-N 2.86Å
152Q90.1Very high88.1Confident51 Ų5141.7 Ų41.724%0.23822%0.218CC..Hα-helixtrans-64.2-38.7177.7-72.9-175.523.500112.6L131 F134 F148 D149 V154 I155 S156L131-Q152 HydrophobicContact CD2-CB 4.02Å; L131-Q152 HydrophobicContact CD2-CG 4.07Å; F134-Q152 HydrophobicContact CB-CG 4.18Å; F134-Q152 PolarHBondContact O-NE2 3.27Å; F148-Q152 WeakPolarHBondContact O-CG 3.47Å; F148-Q152 PolarHBondContact O-N 3.27Å; D149-Q152 PolarHBondContact O-N 3.4Å; Q152-V154 VanDerWaalsContact C-N 3.34Å; Q152-V154 PolarHBondContact O-N 3.13Å; Q152-I155 PolarHBondContact O-N 3.29Å; Q152-S156 VanDerWaalsContact O-CB 3.28Å; Q152-S156 WeakPolarHBondContact O-CB 3.37Å; Q152-S156 PolarHBondContact O-N 2.97Å; Q152-S156 PolarHBondContact O-OG 3.47Å
153A88.6Confident88.4Confident41 Ų4140.6 Ų40.634%0.33921%0.213SC..Hα-helixtrans-62.9-41.217800000111.5D149 D150 V151 S157D149-A153 VanDerWaalsContact O-CB 3.28Å; D149-A153 WeakPolarHBondContact O-CB 3.41Å; D149-A153 PolarHBondContact O-N 2.62Å; D150-A153 PolarHBondContact O-N 2.78Å; V151-A153 PolarHBondContact O-N 2.83Å; A153-S157 VanDerWaalsContact O-CB 3.31Å; A153-S157 WeakPolarHBondContact O-CB 3.48Å; A153-S157 PolarHBondContact O-N 3.13Å
154V90.8Very high88.6Confident1 Ų140.6 Ų40.61%0.00621%0.212CC..Hα-helixtrans-66.2-48.1175.3172.70000111.9M31 L126 D150 V151 Q152 S156 S157 A158 H204 S207 F210M31-V154 HydrophobicContact CE-CB 4.4Å; M31-V154 HydrophobicContact CE-CG2 4.13Å; M31-V154 HydrophobicContact CG-CB 4.34Å; M31-V154 HydrophobicContact CG-CG1 3.81Å; L126-V154 HydrophobicContact CD1-CG1 3.86Å; L126-V154 HydrophobicContact CD2-CG1 4.42Å; D150-V154 WeakPolarHBondContact O-CG2 3.42Å; D150-V154 PolarHBondContact O-N 3.42Å; D150-V154 VanDerWaalsContact O-N 3.13Å; V151-V154 PolarHBondContact O-N 3.48Å; Q152-V154 VanDerWaalsContact C-N 3.34Å; Q152-V154 PolarHBondContact O-N 3.13Å; V154-S156 VanDerWaalsContact C-N 3.31Å; V154-S156 PolarHBondContact O-N 3.5Å; V154-S157 PolarHBondContact O-N 3.35Å; V154-A158 WeakPolarHBondContact O-CB 3.38Å; V154-A158 PolarHBondContact O-N 2.86Å; V154-H204 PolarHBondContact O-NE2 3.36Å; V154-S207 WeakPolarHBondContact CG2-O 3.49Å; V154-F210 HydrophobicContact CG2-CE1 3.34Å; V154-F210 HydrophobicContact CG2-CZ 3.59Å
155I92Very high89.2Confident0 Ų031.3 Ų31.30%017%0.169CC..Hα-helixtrans-58.9-45.7177.8-67.6162.5000110.6T27 L126 T129 L131 F134 V151 Q152 S157 A158 Q159T27-I155 HydrophobicContact CG2-CD1 4.45Å; L126-I155 HydrophobicContact CD2-CG1 4.46Å; T129-I155 HydrophobicContact CG2-CD1 3.62Å; T129-I155 HydrophobicContact CG2-CG1 4.11Å; T129-I155 WeakPolarHBondContact O-CG2 3.23Å; L131-I155 HydrophobicContact CD2-CB 3.65Å; L131-I155 HydrophobicContact CD2-CD1 4.26Å; L131-I155 HydrophobicContact CD2-CG2 3.44Å; L131-I155 VanDerWaalsContact CD2-CG2 3.44Å; L131-I155 HydrophobicContact CG-CG2 3.82Å; F134-I155 HydrophobicContact CD2-CD1 3.63Å; F134-I155 HydrophobicContact CE2-CD1 4.07Å; F134-I155 HydrophobicContact CG-CD1 4.36Å; V151-I155 HydrophobicContact CG1-CD1 3.76Å; V151-I155 WeakPolarHBondContact O-CG1 3.32Å; V151-I155 PolarHBondContact O-N 2.86Å; Q152-I155 PolarHBondContact O-N 3.29Å; I155-S157 PolarHBondContact O-N 3.36Å; I155-A158 PolarHBondContact O-N 3.49Å; I155-Q159 WeakPolarHBondContact O-CG 3.39Å; I155-Q159 PolarHBondContact O-N 3.43Å
156S89.4Confident89.6Confident51 Ų5126.1 Ų26.136%0.35715%0.147SC..Hα-helixtrans-64.5-40.7-180-57.70000111.7Q152 V154 Q159 Q160Q152-S156 VanDerWaalsContact O-CB 3.28Å; Q152-S156 WeakPolarHBondContact O-CB 3.37Å; Q152-S156 PolarHBondContact O-N 2.97Å; Q152-S156 PolarHBondContact O-OG 3.47Å; V154-S156 VanDerWaalsContact C-N 3.31Å; V154-S156 PolarHBondContact O-N 3.5Å; S156-Q159 WeakPolarHBondContact O-CB 3.38Å; S156-Q159 PolarHBondContact O-N 3.05Å; S156-Q160 PolarHBondContact O-N 3.4Å
157S89Confident89.8Confident10 Ų1026.8 Ų26.87%0.0715%0.15CC..Hα-helixtrans-65.3-44.3175.6-168.50000111.4A153 V154 I155 Q159 Q160 I161 H204 S207A153-S157 VanDerWaalsContact O-CB 3.31Å; A153-S157 WeakPolarHBondContact O-CB 3.48Å; A153-S157 PolarHBondContact O-N 3.13Å; V154-S157 PolarHBondContact O-N 3.35Å; I155-S157 PolarHBondContact O-N 3.36Å; S157-Q159 VanDerWaalsContact C-N 3.33Å; S157-Q159 PolarHBondContact O-N 3.05Å; S157-Q160 WeakPolarHBondContact O-CB 3.38Å; S157-Q160 PolarHBondContact O-N 2.94Å; S157-I161 WeakPolarHBondContact O-CG1 3.3Å; S157-I161 PolarHBondContact O-N 3.39Å; S157-H204 WeakPolarHBondContact OG-CA 3.39Å; S157-H204 PolarHBondContact OG-CD2 2.96Å; S157-H204 VanDerWaalsContact OG-CD2 3.3Å; S157-S207 WeakPolarHBondContact CB-OG 3.41Å; S157-S207 PolarHBondContact OG-OG 3.07Å
158A92.3Very high90.1Very high0 Ų025.1 Ų25.10%014%0.137CC..Hα-helixtrans-57-43.9174.600000112.1V123 L126 A127 V154 I155 Q160 I161 C162V123-A158 HydrophobicContact CG1-CB 4.06Å; L126-A158 HydrophobicContact CB-CB 3.71Å; A127-A158 HydrophobicContact CB-CB 4.21Å; V154-A158 WeakPolarHBondContact O-CB 3.38Å; V154-A158 PolarHBondContact O-N 2.86Å; I155-A158 PolarHBondContact O-N 3.49Å; A158-Q160 VanDerWaalsContact C-N 3.31Å; A158-Q160 PolarHBondContact O-N 3.32Å; A158-I161 WeakPolarHBondContact O-CG1 3.5Å; A158-I161 PolarHBondContact O-N 3.01Å; A158-C162 WeakPolarHBondContact O-CB 3.42Å; A158-C162 PolarHBondContact O-N 3.39Å
159Q90.6Very high90.3Very high46 Ų4626.2 Ų26.222%0.21514%0.141CC..Hα-helixtrans-59.6-39.6173.5-74.2173.7-6.500112.7A127 I155 S156 S157 C162 F255A127-Q159 HydrophobicContact CB-CG 4.39Å; A127-Q159 WeakPolarHBondContact O-CG 3.31Å; A127-Q159 PolarHBondContact O-NE2 3.38Å; I155-Q159 WeakPolarHBondContact O-CG 3.39Å; I155-Q159 PolarHBondContact O-N 3.43Å; S156-Q159 WeakPolarHBondContact O-CB 3.38Å; S156-Q159 PolarHBondContact O-N 3.05Å; S157-Q159 VanDerWaalsContact C-N 3.33Å; S157-Q159 PolarHBondContact O-N 3.05Å; Q159-C162 PolarHBondContact O-SG 3.31Å; Q159-C162 VanDerWaalsContact O-SG 3.38Å; Q159-F255 HydrophobicContact CG-CE1 4.07Å; Q159-F255 HydrophobicContact CG-CZ 4.1Å
160Q85.9Confident90.4Very high80 Ų8021.9 Ų21.937%0.37412%0.116SC..Hα-helixtrans-69.5-39.9179.3-175.8-179.4-17.300112.5S156 S157 A158 V390 L393S156-Q160 PolarHBondContact O-N 3.4Å; S157-Q160 WeakPolarHBondContact O-CB 3.38Å; S157-Q160 PolarHBondContact O-N 2.94Å; A158-Q160 VanDerWaalsContact C-N 3.31Å; A158-Q160 PolarHBondContact O-N 3.32Å; Q160-V390 VanDerWaalsContact O-CG2 3.24Å; Q160-V390 WeakPolarHBondContact O-CG2 3.48Å; Q160-L393 HydrophobicContact CG-CD1 4.16Å
161I87.8Confident90.5Very high0 Ų021.6 Ų21.60%012%0.115CC..Hα-helixtrans-88.2-15.8-175.563.5167.2000113.9V123 S157 A158 P163 L164 I200 I203 H204V123-I161 HydrophobicContact CG1-CD1 3.56Å; V123-I161 HydrophobicContact CG1-CG1 3.87Å; V123-I161 HydrophobicContact CG2-CD1 4.37Å; S157-I161 WeakPolarHBondContact O-CG1 3.3Å; S157-I161 PolarHBondContact O-N 3.39Å; A158-I161 WeakPolarHBondContact O-CG1 3.5Å; A158-I161 PolarHBondContact O-N 3.01Å; I161-P163 VanDerWaalsContact C-N 3.29Å; I161-P163 VanDerWaalsContact O-N 3.13Å; I161-L164 WeakPolarHBondContact O-CB 3.28Å; I161-L164 PolarHBondContact O-N 3.48Å; I161-I200 HydrophobicContact CD1-CB 4.48Å; I161-I200 HydrophobicContact CD1-CG2 3.55Å; I161-I203 HydrophobicContact CG2-CB 3.76Å; I161-I203 HydrophobicContact CG2-CD1 4.14Å; I161-I203 HydrophobicContact CG2-CG2 3.39Å; I161-H204 HydrophobicContact CD1-CB 4.05Å
162C90.5Very high90.6Very high0 Ų022.3 Ų22.30%012%0.121CC..G310 helixtrans-57.2-30.4-171.476.60000115A127 A158 Q159 L164 I165 L256 Q258A127-C162 HydrophobicContact CB-CB 3.88Å; A158-C162 WeakPolarHBondContact O-CB 3.42Å; A158-C162 PolarHBondContact O-N 3.39Å; Q159-C162 PolarHBondContact O-SG 3.31Å; Q159-C162 VanDerWaalsContact O-SG 3.38Å; C162-L164 PolarHBondContact O-N 2.95Å; C162-I165 HydrophobicContact CB-CD1 4.19Å; C162-I165 VanDerWaalsContact O-CB 3.25Å; C162-I165 WeakPolarHBondContact O-CB 3.5Å; C162-I165 WeakPolarHBondContact O-CG1 3.46Å; C162-I165 PolarHBondContact O-N 2.76Å; C162-L256 HydrophobicContact CB-CD2 3.88Å; C162-L256 WeakPolarHBondContact O-CD2 3.18Å; C162-Q258 PolarHBondContact SG-NE2 3.31Å
163P91.2Very high90.7Very high3 Ų325.9 Ų25.92%0.01914%0.135CC..G310 helixtrans-58.7-32.8174.2-26.237.3000113.7I161 I165 L166 L256 Q258 V386 M387 V390I161-P163 VanDerWaalsContact C-N 3.29Å; I161-P163 VanDerWaalsContact O-N 3.13Å; P163-I165 PolarHBondContact O-N 2.87Å; P163-L166 WeakPolarHBondContact O-CB 3.47Å; P163-L166 PolarHBondContact O-N 3.45Å; P163-L256 WeakPolarHBondContact CA-O 3.4Å; P163-Q258 HydrophobicContact CG-CB 4.18Å; P163-Q258 HydrophobicContact CG-CG 3.6Å; P163-V386 HydrophobicContact CB-CG1 4.14Å; P163-M387 WeakPolarHBondContact O-CG 3.39Å; P163-V390 HydrophobicContact CB-CG2 3.77Å; P163-V390 HydrophobicContact CG-CG2 3.71Å
164L90.3Very high90.9Very high2 Ų226.4 Ų26.41%0.0113%0.134CC..G310 helixtrans-66.1-17.8178.8-60.5179.5000112.8I161 C162 L166 E167 T196 I200 I203 M387 V390I161-L164 WeakPolarHBondContact O-CB 3.28Å; I161-L164 PolarHBondContact O-N 3.48Å; C162-L164 PolarHBondContact O-N 2.95Å; L164-L166 PolarHBondContact O-N 3.14Å; L164-E167 PolarHBondContact O-N 3.28Å; L164-T196 HydrophobicContact CB-CG2 4.2Å; L164-I200 HydrophobicContact CB-CD1 4.05Å; L164-I200 HydrophobicContact CB-CG1 4.02Å; L164-I200 HydrophobicContact CD1-CG1 3.93Å; L164-I203 HydrophobicContact CD1-CD1 4.37Å; L164-M387 HydrophobicContact CD2-CB 4.34Å; L164-V390 HydrophobicContact CD1-CG1 4.06Å; L164-V390 HydrophobicContact CD2-CB 4.28Å; L164-V390 HydrophobicContact CD2-CG2 4.36Å; L164-V390 HydrophobicContact CG-CB 4.27Å; L164-V390 HydrophobicContact CG-CG1 4.26Å; L164-V390 HydrophobicContact CG-CG2 4.13Å
165I94.1Very high90.9Very high1 Ų126.5 Ų26.51%0.00514%0.135CC..G310 helixtrans-66.8-21.6178.9-56.2179.5000111.3L120 V123 E124 C162 P163 E167 F168 K169 L256L120-I165 HydrophobicContact CB-CG2 4.37Å; L120-I165 HydrophobicContact CD2-CG1 4.16Å; L120-I165 HydrophobicContact CD2-CG2 4.38Å; V123-I165 HydrophobicContact CB-CD1 4.16Å; V123-I165 HydrophobicContact CG1-CD1 3.77Å; E124-I165 HydrophobicContact CG-CD1 3.61Å; E124-I165 HydrophobicContact CG-CG2 4.22Å; E124-I165 VanDerWaalsContact OE1-CG2 3.23Å; E124-I165 WeakPolarHBondContact OE1-CG2 3.36Å; C162-I165 HydrophobicContact CB-CD1 4.19Å; C162-I165 VanDerWaalsContact O-CB 3.25Å; C162-I165 WeakPolarHBondContact O-CB 3.5Å; C162-I165 WeakPolarHBondContact O-CG1 3.46Å; C162-I165 PolarHBondContact O-N 2.76Å; P163-I165 PolarHBondContact O-N 2.87Å; I165-E167 PolarHBondContact O-N 2.85Å; I165-F168 PolarHBondContact O-N 2.84Å; I165-K169 PolarHBondContact O-N 3.21Å; I165-L256 HydrophobicContact CB-CD1 4.34Å; I165-L256 HydrophobicContact CB-CD2 4.44Å; I165-L256 HydrophobicContact CG2-CD1 4.43Å
166L92.3Very high91Very high11 Ų1126.6 Ų26.66%0.05814%0.135CC..G310 helixtrans-56.9-31.2175.6-73.7171.5000113.4P163 L164 F168 K169 M253 L256 F257 L383 V386 M387P163-L166 WeakPolarHBondContact O-CB 3.47Å; P163-L166 PolarHBondContact O-N 3.45Å; L164-L166 PolarHBondContact O-N 3.14Å; L166-F168 PolarHBondContact O-N 3.19Å; L166-K169 HydrophobicContact CD2-CG 4.39Å; L166-K169 PolarHBondContact O-N 3.37Å; L166-M253 HydrophobicContact CD2-SD 4.41Å; L166-L256 HydrophobicContact CD1-CB 4.46Å; L166-L256 HydrophobicContact CD2-CB 4.17Å; L166-L256 HydrophobicContact CD2-CD1 3.88Å; L166-L256 HydrophobicContact CG-CB 4.08Å; L166-L256 HydrophobicContact CG-CD1 4.15Å; L166-F257 HydrophobicContact CD1-CE2 4.43Å; L166-F257 HydrophobicContact CD2-CE2 4.09Å; L166-L383 HydrophobicContact CD1-CD2 4.44Å; L166-V386 HydrophobicContact CD1-CB 3.85Å; L166-V386 HydrophobicContact CD1-CG1 3.47Å; L166-V386 VanDerWaalsContact CD1-CG1 3.47Å; L166-V386 HydrophobicContact CD1-CG2 4.41Å; L166-M387 HydrophobicContact CB-CG 4.28Å; L166-M387 HydrophobicContact CB-SD 4.26Å
167E89.5Confident91.2Very high22 Ų2228.8 Ų28.810%0.10314%0.142CC..G310 helixtrans-58.9-32.4175.8-175.860-150.700111.3L164 I165 Q189 Y193 T196 M387L164-E167 PolarHBondContact O-N 3.28Å; I165-E167 PolarHBondContact O-N 2.85Å; E167-Q189 PolarHBondContact OE1-NE2 3.49Å; E167-Y193 HydrophobicContact CG-CD1 4.03Å; E167-Y193 HydrophobicContact CG-CE1 4.04Å; E167-Y193 WeakPolarHBondContact O-CE1 3.33Å; E167-T196 HydrophobicContact CB-CG2 4.14Å; E167-T196 HydrophobicContact CG-CG2 4.39Å; E167-M387 HydrophobicContact CB-SD 4.07Å
168F93.4Very high91.5Very high14 Ų1430.6 Ų30.66%0.06115%0.154CC..G310 helixtrans-93.2-3.1-176.7-54.5-78.7000114.2L116 L120 I165 L166 R170 Y193 T196 A197 I200L116-F168 HydrophobicContact CD2-CD1 3.72Å; L116-F168 HydrophobicContact CD2-CE1 3.46Å; L116-F168 VanDerWaalsContact CD2-CE1 3.46Å; L116-F168 HydrophobicContact CD2-CZ 4.12Å; L120-F168 HydrophobicContact CD1-CB 3.51Å; L120-F168 HydrophobicContact CD1-CD1 4.12Å; L120-F168 HydrophobicContact CD1-CD2 3.67Å; L120-F168 HydrophobicContact CD1-CE2 4.4Å; L120-F168 HydrophobicContact CD1-CG 3.5Å; L120-F168 VanDerWaalsContact CD1-CG 3.5Å; L120-F168 HydrophobicContact CD2-CD2 4.07Å; L120-F168 HydrophobicContact CD2-CE2 4.26Å; I165-F168 PolarHBondContact O-N 2.84Å; L166-F168 PolarHBondContact O-N 3.19Å; F168-R170 PolarHBondContact O-N 2.94Å; F168-Y193 AromaticContact CD1-CD1 3.72Å; F168-Y193 HydrophobicContact CD1-CD1 3.72Å; F168-Y193 HydrophobicContact CD1-CD2 4.45Å; F168-Y193 HydrophobicContact CD1-CE1 4.03Å; F168-Y193 AromaticContact CD1-CG 3.95Å; F168-Y193 HydrophobicContact CD1-CG 3.95Å; F168-Y193 AromaticContact CE1-CD1 3.72Å; F168-Y193 HydrophobicContact CE1-CD1 3.72Å; F168-Y193 HydrophobicContact CE1-CE1 4.47Å; F168-Y193 AromaticContact CE1-CG 3.8Å; F168-Y193 HydrophobicContact CE1-CG 3.8Å; F168-T196 HydrophobicContact CE2-CG2 3.57Å; F168-T196 HydrophobicContact CZ-CG2 3.81Å; F168-A197 HydrophobicContact CZ-CB 4.15Å; F168-I200 HydrophobicContact CE2-CD1 3.78Å
169K93.1Very high91.3Very high52 Ų5232.8 Ų32.823%0.22617%0.165CC..  trans-72.43.3179.3-67.7-56.6-164.7-177.60114.2E124 I165 L166 M253 L256 I497E124-K169 WeakPolarHBondContact OE1-CE 3.22Å; E124-K169 IonicContact OE1-NZ 3.4Å; E124-K169 PolarHBondContact OE1-NZ 3.1Å; E124-K169 IonicContact OE2-NZ 3.73Å; E124-K169 PolarHBondContact OE2-NZ 3.47Å; I165-K169 PolarHBondContact O-N 3.21Å; L166-K169 HydrophobicContact CD2-CG 4.39Å; L166-K169 PolarHBondContact O-N 3.37Å; K169-M253 HydrophobicContact CD-CE 3.87Å; K169-M253 HydrophobicContact CD-SD 4.35Å; K169-M253 HydrophobicContact CG-CE 4.22Å; K169-M253 HydrophobicContact CG-SD 4.21Å; K169-L256 VanDerWaalsContact CE-CD1 3.45Å; K169-L256 HydrophobicContact CG-CD1 4.38Å; K169-I497 HydrophobicContact CB-CD1 3.91Å; K169-I497 HydrophobicContact CB-CG1 4.18Å
170R89.9Confident91.1Very high26 Ų2630.9 Ų30.910%0.09816%0.157CC..SBendtrans-72.1142.3170.7-169.8-177.5-57175.18.4110.7F168 A172 F175 Q189 Y193F168-R170 PolarHBondContact O-N 2.94Å; R170-A172 PolarHBondContact O-N 2.92Å; R170-F175 VanDerWaalsContact CD-CD2 3.41Å; R170-F175 HydrophobicContact CG-CB 4.32Å; R170-F175 HydrophobicContact CG-CD2 4.36Å; R170-F175 HydrophobicContact CG-CG 4.42Å; R170-F175 VanDerWaalsContact NH1-CE1 3.31Å; R170-Q189 VanDerWaalsContact CZ-OE1 3.22Å; R170-Q189 VanDerWaalsContact NH2-CD 3.33Å; R170-Y193 WeakPolarHBondContact CB-OH 3.48Å
171D89.2Confident90.8Very high43 Ų4328.6 Ų28.623%0.2315%0.146CC..  trans-71.696.5172.4-172.7-42.3000111K173 T174 F175 S493 K496D171-K173 VanDerWaalsContact C-N 3.28Å; D171-K173 PolarHBondContact O-N 3.36Å; D171-K173 PolarHBondContact OD1-N 2.81Å; D171-T174 HydrophobicContact CB-CG2 4.5Å; D171-T174 WeakPolarHBondContact CB-OG1 3.31Å; D171-T174 PolarHBondContact O-N 3.11Å; D171-T174 PolarHBondContact O-OG1 2.86Å; D171-T174 VanDerWaalsContact O-OG1 3.05Å; D171-T174 WeakPolarHBondContact OD1-CG2 3.28Å; D171-T174 PolarHBondContact OD1-N 3.16Å; D171-T174 PolarHBondContact OD1-OG1 3.38Å; D171-F175 WeakPolarHBondContact O-CB 3.35Å; D171-F175 PolarHBondContact O-N 3.07Å; D171-S493 PolarHBondContact N-OG 3.2Å; D171-K496 IonicContact OD2-NZ 3.8Å; D171-K496 PolarHBondContact OD2-NZ 2.67Å
172A92.2Very high90.6Very high15 Ų1529 Ų2912%0.12415%0.148CC..Hα-helixtrans-57.9-38.2-177.400000112.9L110 L113 R170 T174 F175 F176L110-A172 HydrophobicContact CD2-CB 3.89Å; L113-A172 HydrophobicContact CD1-CB 3.87Å; R170-A172 PolarHBondContact O-N 2.92Å; A172-T174 PolarHBondContact O-N 3.46Å; A172-F175 PolarHBondContact O-N 2.61Å; A172-F176 HydrophobicContact CB-CD2 4.21Å; A172-F176 WeakPolarHBondContact O-CB 3.49Å; A172-F176 WeakPolarHBondContact O-CD2 3.34Å; A172-F176 PolarHBondContact O-N 3.01Å
173K93.2Very high90.4Very high126 Ų12629.2 Ų29.255%0.54815%0.149SC..Hα-helixtrans-67-38.1-177-68.4-176.7178.9-178.40112L110 E114 D171L110-K173 HydrophobicContact CD2-CG 4.2Å; E114-K173 WeakPolarHBondContact OE1-CE 3.49Å; E114-K173 IonicContact OE1-NZ 3.18Å; E114-K173 PolarHBondContact OE1-NZ 3.3Å; D171-K173 VanDerWaalsContact C-N 3.28Å; D171-K173 PolarHBondContact O-N 3.36Å; D171-K173 PolarHBondContact OD1-N 2.81Å
174T91.7Very high90Very high52 Ų5231 Ų3132%0.31916%0.158SC..Hα-helixtrans-80.3-25.2176.264.70000113.1D171 A172 L177 S489D171-T174 HydrophobicContact CB-CG2 4.5Å; D171-T174 WeakPolarHBondContact CB-OG1 3.31Å; D171-T174 PolarHBondContact O-N 3.11Å; D171-T174 PolarHBondContact O-OG1 2.86Å; D171-T174 VanDerWaalsContact O-OG1 3.05Å; D171-T174 WeakPolarHBondContact OD1-CG2 3.28Å; D171-T174 PolarHBondContact OD1-N 3.16Å; D171-T174 PolarHBondContact OD1-OG1 3.38Å; A172-T174 PolarHBondContact O-N 3.46Å; T174-L177 WeakPolarHBondContact O-CD1 3.45Å; T174-L177 WeakPolarHBondContact O-CG 3.5Å; T174-S489 PolarHBondContact OG1-OG 2.9Å
175F91.7Very high89.6Confident2 Ų231 Ų311%0.00916%0.157CC..Hα-helixtrans-83.4-48.4-178.2-169-95.4000112.8R170 D171 A172 L177 V185 L186 Q189 L452 L486R170-F175 VanDerWaalsContact CD-CD2 3.41Å; R170-F175 HydrophobicContact CG-CB 4.32Å; R170-F175 HydrophobicContact CG-CD2 4.36Å; R170-F175 HydrophobicContact CG-CG 4.42Å; R170-F175 VanDerWaalsContact NH1-CE1 3.31Å; D171-F175 WeakPolarHBondContact O-CB 3.35Å; D171-F175 PolarHBondContact O-N 3.07Å; A172-F175 PolarHBondContact O-N 2.61Å; F175-L177 PolarHBondContact O-N 3.29Å; F175-V185 HydrophobicContact CZ-CG1 4.02Å; F175-L186 HydrophobicContact CD1-CD2 3.95Å; F175-L186 HydrophobicContact CE1-CD2 3.84Å; F175-L186 VanDerWaalsContact O-CD2 3.3Å; F175-L186 WeakPolarHBondContact O-CD2 3.36Å; F175-Q189 HydrophobicContact CD1-CG 4.41Å; F175-Q189 HydrophobicContact CE1-CB 3.75Å; F175-Q189 HydrophobicContact CE1-CG 3.82Å; F175-Q189 HydrophobicContact CZ-CB 4.35Å; F175-Q189 HydrophobicContact CZ-CG 4.41Å; F175-L452 HydrophobicContact CE2-CD2 3.71Å; F175-L452 HydrophobicContact CZ-CD2 4.01Å; F175-L486 HydrophobicContact CD2-CD2 3.87Å; F175-L486 HydrophobicContact CE1-CD2 4.39Å; F175-L486 HydrophobicContact CE2-CD2 3.66Å; F175-L486 HydrophobicContact CG-CD2 4.38Å; F175-L486 HydrophobicContact CZ-CD2 3.91Å
176F94.3Very high89.4Confident3 Ų331 Ų311%0.01316%0.157CC..SBendtrans-84.258.5-176.3-73.5-84.9000112.1L106 T109 L110 L113 A172 L186 Q189 L190 Y193L106-F176 HydrophobicContact CD2-CB 3.93Å; L106-F176 HydrophobicContact CD2-CD1 3.68Å; L106-F176 HydrophobicContact CD2-CG 4.28Å; T109-F176 HydrophobicContact CG2-CD1 4.38Å; T109-F176 HydrophobicContact CG2-CE1 4.39Å; L110-F176 HydrophobicContact CD2-CB 4.25Å; L113-F176 HydrophobicContact CD1-CD2 4.14Å; L113-F176 HydrophobicContact CD1-CE2 3.87Å; L113-F176 HydrophobicContact CD1-CZ 4.45Å; A172-F176 HydrophobicContact CB-CD2 4.21Å; A172-F176 WeakPolarHBondContact O-CB 3.49Å; A172-F176 WeakPolarHBondContact O-CD2 3.34Å; A172-F176 PolarHBondContact O-N 3.01Å; F176-L186 HydrophobicContact CD1-CB 4.11Å; F176-L186 HydrophobicContact CD1-CD2 4.08Å; F176-L186 HydrophobicContact CE1-CB 4.2Å; F176-L186 WeakPolarHBondContact CE1-O 3.43Å; F176-Q189 HydrophobicContact CE2-CG 4.46Å; F176-Q189 HydrophobicContact CZ-CB 4.15Å; F176-Q189 HydrophobicContact CZ-CG 3.99Å; F176-L190 HydrophobicContact CE1-CB 4.24Å; F176-L190 HydrophobicContact CZ-CB 4.45Å; F176-Y193 HydrophobicContact CE2-CD2 4.35Å; F176-Y193 AromaticContact CE2-CE2 3.77Å; F176-Y193 HydrophobicContact CE2-CE2 3.77Å; F176-Y193 HydrophobicContact CZ-CD2 4.35Å; F176-Y193 HydrophobicContact CZ-CE2 4.14Å
177L94.2Very high89Confident97 Ų9730.4 Ų30.451%0.50815%0.154SC..  trans-89.5142.8175-66.3176.5000111.6T174 F175 N179 L186T174-L177 WeakPolarHBondContact O-CD1 3.45Å; T174-L177 WeakPolarHBondContact O-CG 3.5Å; F175-L177 PolarHBondContact O-N 3.29Å; L177-N179 VanDerWaalsContact C-N 3.32Å; L177-N179 PolarHBondContact O-N 3.1Å; L177-L186 WeakPolarHBondContact O-CD1 3.46Å
178P93.9Very high88.6Confident48 Ų4832.6 Ų32.631%0.31216%0.164SC..  trans-71.284.8-177.429.2-35.2000111.4E99 L102 A103 L106E99-P178 HydrophobicContact CG-CB 4.43Å; E99-P178 WeakPolarHBondContact CG-O 3.09Å; L102-P178 HydrophobicContact CG-CB 4.39Å; A103-P178 HydrophobicContact CB-CB 3.73Å; A103-P178 HydrophobicContact CB-CG 3.95Å; L106-P178 VanDerWaalsContact CD1-CA 3.49Å; L106-P178 HydrophobicContact CD1-CB 3.98Å
179N88.9Confident88.3Confident45 Ų4532 Ų3224%0.24116%0.161CC..  trans-130.6112.3177.5-168-44.8000110.4L177 H181 N182 V183 A482L177-N179 VanDerWaalsContact C-N 3.32Å; L177-N179 PolarHBondContact O-N 3.1Å; N179-H181 PolarHBondContact O-N 3.07Å; N179-H181 VanDerWaalsContact O-N 3.1Å; N179-H181 VanDerWaalsContact OD1-CB 3.3Å; N179-H181 WeakPolarHBondContact OD1-CB 3.31Å; N179-H181 PolarHBondContact OD1-N 3.15Å; N179-N182 HydrophobicContact CB-CB 4.41Å; N179-N182 WeakPolarHBondContact O-CA 3.39Å; N179-N182 PolarHBondContact O-N 3.47Å; N179-V183 PolarHBondContact O-N 2.99Å; N179-A482 WeakPolarHBondContact ND2-CB 3.36Å
180L85.3Confident88.2Confident7 Ų729.5 Ų29.54%0.03715%0.15CC..THydrogen-bonded Turntrans-59.5-24.1-177.9-66.2178.5000113.8I58 F69 L95 L98 E99 L102 N182 V183I58-L180 HydrophobicContact CG2-CD2 3.53Å; F69-L180 HydrophobicContact CD1-CB 4.5Å; F69-L180 HydrophobicContact CE1-CB 3.76Å; F69-L180 HydrophobicContact CZ-CB 4.12Å; L95-L180 HydrophobicContact CB-CD1 4.2Å; L95-L180 HydrophobicContact CD2-CD1 4.06Å; L95-L180 WeakPolarHBondContact O-CD1 3.24Å; L98-L180 HydrophobicContact CB-CD1 4.21Å; L98-L180 HydrophobicContact CB-CD2 4.19Å; E99-L180 HydrophobicContact CB-CD1 4.25Å; E99-L180 HydrophobicContact CB-CG 4.18Å; E99-L180 HydrophobicContact CG-CG 4.47Å; L102-L180 HydrophobicContact CD2-CD2 4.09Å; L180-N182 PolarHBondContact O-N 3.23Å; L180-V183 WeakPolarHBondContact O-CG1 3.27Å
181H79.4Confident88Confident32 Ų3230.3 Ų30.315%0.14816%0.155CC..THydrogen-bonded Turntrans-70.7-14.8175.1-67.8-59.7000113.7F69 N179 F479 A482 R483F69-H181 AromaticContact CD1-ND1 3.62Å; F69-H181 AromaticContact CE1-CE1 3.27Å; F69-H181 WeakPolarHBondContact CE1-CE1 3.26Å; F69-H181 AromaticContact CE1-CG 3.83Å; F69-H181 AromaticContact CE1-ND1 3.16Å; F69-H181 WeakPolarHBondContact CE1-ND1 3.2Å; F69-H181 AromaticContact CE1-NE2 4Å; F69-H181 AromaticContact CZ-CE1 3.69Å; N179-H181 PolarHBondContact O-N 3.07Å; N179-H181 VanDerWaalsContact O-N 3.1Å; N179-H181 VanDerWaalsContact OD1-CB 3.3Å; N179-H181 WeakPolarHBondContact OD1-CB 3.31Å; N179-H181 PolarHBondContact OD1-N 3.15Å; H181-F479 HydrophobicContact CB-CD2 3.97Å; H181-A482 HydrophobicContact CB-CB 3.88Å; H181-R483 PolarHBondContact O-NH2 2.9Å
182N85.1Confident87.7Confident9 Ų930.7 Ų30.75%0.04816%0.157CC..THydrogen-bonded Turntrans-118.3-5.2-173.7-68-17.3000112.8N179 L180 E184 V185 L186 A482 R483 L486N179-N182 HydrophobicContact CB-CB 4.41Å; N179-N182 WeakPolarHBondContact O-CA 3.39Å; N179-N182 PolarHBondContact O-N 3.47Å; L180-N182 PolarHBondContact O-N 3.23Å; N182-E184 PolarHBondContact O-N 3.16Å; N182-V185 WeakPolarHBondContact O-CA 3.49Å; N182-V185 VanDerWaalsContact O-CB 3.31Å; N182-V185 WeakPolarHBondContact O-CB 3.4Å; N182-V185 PolarHBondContact O-N 3.13Å; N182-L186 WeakPolarHBondContact O-CG 3.37Å; N182-L186 PolarHBondContact O-N 3.21Å; N182-A482 PolarHBondContact ND2-O 3.23Å; N182-R483 PolarHBondContact OD1-NE 3.47Å; N182-L486 HydrophobicContact CB-CD1 3.71Å; N182-L486 HydrophobicContact CB-CG 4.41Å; N182-L486 VanDerWaalsContact ND2-CD1 3.3Å; N182-L486 WeakPolarHBondContact ND2-CD1 3.28Å; N182-L486 VanDerWaalsContact ND2-CG 3.34Å; N182-L486 WeakPolarHBondContact ND2-CG 3.37Å; N182-L486 WeakPolarHBondContact OD1-CD1 3.03Å
183V85.5Confident87.6Confident3 Ų330.2 Ų30.22%0.01815%0.152CC..Hα-helixtrans-51.3-37.1-174.466.60000113.6M55 I58 K59 L102 N179 L180 L186 A187M55-V183 HydrophobicContact CB-CG2 3.94Å; M55-V183 VanDerWaalsContact O-CG2 3.27Å; M55-V183 WeakPolarHBondContact O-CG2 3.49Å; I58-V183 HydrophobicContact CG2-CG2 4.34Å; K59-V183 HydrophobicContact CB-CG1 3.65Å; K59-V183 HydrophobicContact CG-CG1 3.82Å; L102-V183 HydrophobicContact CD1-CG2 3.85Å; L102-V183 HydrophobicContact CD2-CB 4.19Å; L102-V183 HydrophobicContact CD2-CG2 4.2Å; N179-V183 PolarHBondContact O-N 2.99Å; L180-V183 WeakPolarHBondContact O-CG1 3.27Å; V183-L186 PolarHBondContact O-N 2.94Å; V183-A187 WeakPolarHBondContact O-CB 3.47Å; V183-A187 PolarHBondContact O-N 3.45Å
184E82.3Confident87.3Confident42 Ų4224.2 Ų24.220%0.19613%0.126CC..Hα-helixtrans-63.1-47.4173.5177.3167.2-137.900112.1K59 N182 L186 A187 F188 L454K59-E184 HydrophobicContact CD-CB 4.01Å; K59-E184 WeakPolarHBondContact CE-OE2 3.39Å; K59-E184 IonicContact NZ-OE1 2.65Å; K59-E184 PolarHBondContact NZ-OE1 2.81Å; K59-E184 IonicContact NZ-OE2 2.67Å; K59-E184 PolarHBondContact NZ-OE2 3.13Å; N182-E184 PolarHBondContact O-N 3.16Å; E184-L186 VanDerWaalsContact C-N 3.29Å; E184-L186 PolarHBondContact O-N 3.46Å; E184-A187 PolarHBondContact O-N 3.21Å; E184-F188 HydrophobicContact CG-CD2 3.73Å; E184-F188 HydrophobicContact CG-CE2 3.83Å; E184-F188 VanDerWaalsContact O-CD2 3.28Å; E184-F188 WeakPolarHBondContact O-CD2 3.29Å; E184-F188 PolarHBondContact O-N 3.19Å; E184-L454 HydrophobicContact CG-CB 4.35Å; E184-L454 HydrophobicContact CG-CD1 4.37Å
185V82.8Confident87Confident0 Ų025.3 Ų25.30%013%0.13CC..Hα-helixtrans-60.8-42.3178-176.80000110.5F175 N182 Q189 V451 L452 R483 L486F175-V185 HydrophobicContact CZ-CG1 4.02Å; N182-V185 WeakPolarHBondContact O-CA 3.49Å; N182-V185 VanDerWaalsContact O-CB 3.31Å; N182-V185 WeakPolarHBondContact O-CB 3.4Å; N182-V185 PolarHBondContact O-N 3.13Å; V185-Q189 WeakPolarHBondContact O-CB 3.36Å; V185-Q189 PolarHBondContact O-N 3.42Å; V185-V451 HydrophobicContact CB-CG1 4.43Å; V185-V451 HydrophobicContact CG1-CG1 3.82Å; V185-V451 WeakPolarHBondContact O-CG1 3.39Å; V185-L452 HydrophobicContact CG1-CD2 4.07Å; V185-R483 VanDerWaalsContact CG2-CZ 3.46Å; V185-L486 HydrophobicContact CB-CD1 4.16Å; V185-L486 HydrophobicContact CG1-CD1 3.94Å; V185-L486 HydrophobicContact CG2-CD1 4.27Å
186L89.9Confident86.7Confident1 Ų125.9 Ų25.91%0.00513%0.134CC..Hα-helixtrans-62.4-47.8177.6-58.1-177.5000111.1M55 L106 F175 F176 L177 N182 V183 E184 Q189 L190 L486M55-L186 HydrophobicContact SD-CB 4.14Å; L106-L186 HydrophobicContact CD1-CD1 3.97Å; L106-L186 HydrophobicContact CD2-CD1 3.93Å; F175-L186 HydrophobicContact CD1-CD2 3.95Å; F175-L186 HydrophobicContact CE1-CD2 3.84Å; F175-L186 VanDerWaalsContact O-CD2 3.3Å; F175-L186 WeakPolarHBondContact O-CD2 3.36Å; F176-L186 HydrophobicContact CD1-CB 4.11Å; F176-L186 HydrophobicContact CD1-CD2 4.08Å; F176-L186 HydrophobicContact CE1-CB 4.2Å; F176-L186 WeakPolarHBondContact CE1-O 3.43Å; L177-L186 WeakPolarHBondContact O-CD1 3.46Å; N182-L186 WeakPolarHBondContact O-CG 3.37Å; N182-L186 PolarHBondContact O-N 3.21Å; V183-L186 PolarHBondContact O-N 2.94Å; E184-L186 VanDerWaalsContact C-N 3.29Å; E184-L186 PolarHBondContact O-N 3.46Å; L186-Q189 PolarHBondContact O-N 3.43Å; L186-L190 PolarHBondContact O-N 2.92Å; L186-L486 HydrophobicContact CD2-CD2 4.34Å
187A83.2Confident86.5Confident0 Ų025.7 Ų25.70%013%0.133CC..Hα-helixtrans-60.1-50.4178.700000111.4Y52 M55 M56 V183 E184 Q189 L190 Q191Y52-A187 HydrophobicContact CD2-CB 3.73Å; Y52-A187 VanDerWaalsContact CD2-O 3.23Å; Y52-A187 WeakPolarHBondContact CD2-O 3.49Å; Y52-A187 HydrophobicContact CE2-CB 3.84Å; M55-A187 HydrophobicContact CB-CB 3.9Å; M55-A187 HydrophobicContact SD-CB 4.23Å; M56-A187 HydrophobicContact CG-CB 4.21Å; M56-A187 HydrophobicContact SD-CB 3.92Å; V183-A187 WeakPolarHBondContact O-CB 3.47Å; V183-A187 PolarHBondContact O-N 3.45Å; E184-A187 PolarHBondContact O-N 3.21Å; A187-Q189 VanDerWaalsContact C-N 3.28Å; A187-Q189 PolarHBondContact O-N 3.35Å; A187-L190 WeakPolarHBondContact O-CB 3.48Å; A187-L190 PolarHBondContact O-N 3.29Å; A187-L190 VanDerWaalsContact O-N 3.15Å; A187-Q191 PolarHBondContact O-N 3.04Å
188F82.6Confident86.1Confident67 Ų6723.4 Ų23.429%0.29412%0.121SC..Hα-helixtrans-64.2-32.8178.8-85.6-82.2000112.8E184 Q191 N192 V451 L454E184-F188 HydrophobicContact CG-CD2 3.73Å; E184-F188 HydrophobicContact CG-CE2 3.83Å; E184-F188 VanDerWaalsContact O-CD2 3.28Å; E184-F188 WeakPolarHBondContact O-CD2 3.29Å; E184-F188 PolarHBondContact O-N 3.19Å; F188-Q191 PolarHBondContact O-N 3.47Å; F188-N192 PolarHBondContact O-N 3.3Å; F188-N192 VanDerWaalsContact O-N 3.07Å; F188-N192 PolarHBondContact O-OD1 3.47Å; F188-V451 HydrophobicContact CB-CB 4.43Å; F188-V451 HydrophobicContact CB-CG1 3.55Å; F188-V451 HydrophobicContact CB-CG2 4Å; F188-L454 HydrophobicContact CB-CD1 3.61Å; F188-L454 HydrophobicContact CD1-CD1 4.01Å; F188-L454 HydrophobicContact CD2-CD1 3.26Å; F188-L454 HydrophobicContact CE2-CD1 3.84Å; F188-L454 HydrophobicContact CG-CD1 3.35Å; F188-L454 HydrophobicContact CZ-CD1 4.43Å
189Q87.1Confident85.7Confident2 Ų223.2 Ų23.21%0.00911%0.114CC..Hα-helixtrans-68.1-41.6173.4-175.561.642.800111.7E167 R170 F175 F176 V185 L186 A187 Q191 N192 Y193 V451E167-Q189 PolarHBondContact OE1-NE2 3.49Å; R170-Q189 VanDerWaalsContact CZ-OE1 3.22Å; R170-Q189 VanDerWaalsContact NH2-CD 3.33Å; F175-Q189 HydrophobicContact CD1-CG 4.41Å; F175-Q189 HydrophobicContact CE1-CB 3.75Å; F175-Q189 HydrophobicContact CE1-CG 3.82Å; F175-Q189 HydrophobicContact CZ-CB 4.35Å; F175-Q189 HydrophobicContact CZ-CG 4.41Å; F176-Q189 HydrophobicContact CE2-CG 4.46Å; F176-Q189 HydrophobicContact CZ-CB 4.15Å; F176-Q189 HydrophobicContact CZ-CG 3.99Å; V185-Q189 WeakPolarHBondContact O-CB 3.36Å; V185-Q189 PolarHBondContact O-N 3.42Å; L186-Q189 PolarHBondContact O-N 3.43Å; A187-Q189 VanDerWaalsContact C-N 3.28Å; A187-Q189 PolarHBondContact O-N 3.35Å; Q189-Q191 VanDerWaalsContact C-N 3.25Å; Q189-Q191 PolarHBondContact O-N 3Å; Q189-N192 WeakPolarHBondContact O-CB 3.42Å; Q189-N192 PolarHBondContact O-N 3.24Å; Q189-N192 VanDerWaalsContact O-N 3.13Å; Q189-Y193 HydrophobicContact CG-CE1 4.27Å; Q189-Y193 HydrophobicContact CG-CE2 4.29Å; Q189-Y193 PolarHBondContact O-N 3.33Å; Q189-V451 HydrophobicContact CB-CG1 4.39Å
190L89.6Confident85.5Confident0 Ų021 Ų210%010%0.103CC..Hα-helixtrans-59.6-40.9175.5-178.657.2000110.8R48 E51 M55 T109 F176 L186 A187 N192 Y193 I194R48-L190 HydrophobicContact CB-CD1 4.23Å; R48-L190 HydrophobicContact CG-CD1 4.42Å; E51-L190 HydrophobicContact CB-CD2 3.93Å; M55-L190 HydrophobicContact CE-CD2 4Å; T109-L190 HydrophobicContact CG2-CD1 3.81Å; T109-L190 HydrophobicContact CG2-CD2 4.09Å; F176-L190 HydrophobicContact CE1-CB 4.24Å; F176-L190 HydrophobicContact CZ-CB 4.45Å; L186-L190 PolarHBondContact O-N 2.92Å; A187-L190 WeakPolarHBondContact O-CB 3.48Å; A187-L190 PolarHBondContact O-N 3.29Å; A187-L190 VanDerWaalsContact O-N 3.15Å; L190-N192 PolarHBondContact O-N 3.14Å; L190-Y193 WeakPolarHBondContact O-CB 3.48Å; L190-Y193 PolarHBondContact O-N 3.27Å; L190-Y193 VanDerWaalsContact O-N 3.16Å; L190-I194 HydrophobicContact CG-CD1 4.21Å; L190-I194 VanDerWaalsContact O-CG1 3.31Å; L190-I194 WeakPolarHBondContact O-CG1 3.45Å; L190-I194 PolarHBondContact O-N 2.92Å
191Q85.2Confident85.5Confident43 Ų4321 Ų2120%0.20110%0.103CC..Hα-helixtrans-59.3-44.2173.3-172.665.555.500112.2Y52 A187 F188 Q189 Y193 I194 D195Y52-Q191 HydrophobicContact CD2-CB 4.24Å; Y52-Q191 HydrophobicContact CE2-CB 4.24Å; A187-Q191 PolarHBondContact O-N 3.04Å; F188-Q191 PolarHBondContact O-N 3.47Å; Q189-Q191 VanDerWaalsContact C-N 3.25Å; Q189-Q191 PolarHBondContact O-N 3Å; Q191-Y193 VanDerWaalsContact C-N 3.26Å; Q191-Y193 PolarHBondContact O-N 2.98Å; Q191-I194 PolarHBondContact O-N 2.84Å; Q191-D195 PolarHBondContact NE2-OD1 3.17Å; Q191-D195 WeakPolarHBondContact O-CB 3.41Å; Q191-D195 VanDerWaalsContact O-CG 3.31Å; Q191-D195 PolarHBondContact O-N 3.31Å
192N83.4Confident85.5Confident51 Ų5122.7 Ų22.727%0.27312%0.115SC..Hα-helixtrans-59.8-37.9176.1-72.4-1.6000112.1F188 Q189 L190 T196 V451F188-N192 PolarHBondContact O-N 3.3Å; F188-N192 VanDerWaalsContact O-N 3.07Å; F188-N192 PolarHBondContact O-OD1 3.47Å; Q189-N192 WeakPolarHBondContact O-CB 3.42Å; Q189-N192 PolarHBondContact O-N 3.24Å; Q189-N192 VanDerWaalsContact O-N 3.13Å; L190-N192 PolarHBondContact O-N 3.14Å; N192-T196 WeakPolarHBondContact O-CB 3.38Å; N192-T196 PolarHBondContact O-N 2.88Å; N192-T196 PolarHBondContact O-OG1 3.33Å; N192-V451 WeakPolarHBondContact ND2-CG2 3.45Å
193Y91.3Very high84.9Confident4 Ų423.5 Ų23.52%0.01612%0.119CC..Hα-helixtrans-66.4-43.9175.5-72.7-7.4000112.4L113 E167 F168 R170 F176 Q189 L190 Q191 T196 A197L113-Y193 HydrophobicContact CD1-CD2 4.06Å; L113-Y193 HydrophobicContact CD1-CE2 4.08Å; L113-Y193 HydrophobicContact CD2-CD2 3.7Å; L113-Y193 HydrophobicContact CD2-CE2 4.37Å; E167-Y193 HydrophobicContact CG-CD1 4.03Å; E167-Y193 HydrophobicContact CG-CE1 4.04Å; E167-Y193 WeakPolarHBondContact O-CE1 3.33Å; F168-Y193 AromaticContact CD1-CD1 3.72Å; F168-Y193 HydrophobicContact CD1-CD1 3.72Å; F168-Y193 HydrophobicContact CD1-CD2 4.45Å; F168-Y193 HydrophobicContact CD1-CE1 4.03Å; F168-Y193 AromaticContact CD1-CG 3.95Å; F168-Y193 HydrophobicContact CD1-CG 3.95Å; F168-Y193 AromaticContact CE1-CD1 3.72Å; F168-Y193 HydrophobicContact CE1-CD1 3.72Å; F168-Y193 HydrophobicContact CE1-CE1 4.47Å; F168-Y193 AromaticContact CE1-CG 3.8Å; F168-Y193 HydrophobicContact CE1-CG 3.8Å; R170-Y193 WeakPolarHBondContact CB-OH 3.48Å; F176-Y193 HydrophobicContact CE2-CD2 4.35Å; F176-Y193 AromaticContact CE2-CE2 3.77Å; F176-Y193 HydrophobicContact CE2-CE2 3.77Å; F176-Y193 HydrophobicContact CZ-CD2 4.35Å; F176-Y193 HydrophobicContact CZ-CE2 4.14Å; Q189-Y193 HydrophobicContact CG-CE1 4.27Å; Q189-Y193 HydrophobicContact CG-CE2 4.29Å; Q189-Y193 PolarHBondContact O-N 3.33Å; L190-Y193 WeakPolarHBondContact O-CB 3.48Å; L190-Y193 PolarHBondContact O-N 3.27Å; L190-Y193 VanDerWaalsContact O-N 3.16Å; Q191-Y193 VanDerWaalsContact C-N 3.26Å; Q191-Y193 PolarHBondContact O-N 2.98Å; Y193-T196 PolarHBondContact O-N 3.17Å; Y193-A197 WeakPolarHBondContact O-CB 3.31Å; Y193-A197 PolarHBondContact O-N 3.05Å
194I86.6Confident84.2Confident0 Ų023.4 Ų23.40%012%0.119CC..Hα-helixtrans-59.1-49.8174.9-65.6164.2000110.4K45 R48 E49 L190 Q191 T196 A197 N198K45-I194 HydrophobicContact CG-CG2 3.99Å; R48-I194 HydrophobicContact CB-CD1 3.56Å; R48-I194 HydrophobicContact CB-CG1 3.61Å; R48-I194 HydrophobicContact CG-CG1 4.43Å; E49-I194 HydrophobicContact CG-CD1 4.01Å; E49-I194 HydrophobicContact CG-CG2 4.34Å; L190-I194 HydrophobicContact CG-CD1 4.21Å; L190-I194 VanDerWaalsContact O-CG1 3.31Å; L190-I194 WeakPolarHBondContact O-CG1 3.45Å; L190-I194 PolarHBondContact O-N 2.92Å; Q191-I194 PolarHBondContact O-N 2.84Å; I194-T196 PolarHBondContact O-N 3.05Å; I194-A197 PolarHBondContact O-N 3.2Å; I194-N198 VanDerWaalsContact O-CB 3.29Å; I194-N198 WeakPolarHBondContact O-CB 3.34Å; I194-N198 PolarHBondContact O-N 2.86Å
195D84.1Confident83.5Confident76 Ų7624.1 Ų24.141%0.40613%0.128SC..Hα-helixtrans-63.6-42.5-177-70.6-10.1000111.3Q191 N198 R199Q191-D195 PolarHBondContact NE2-OD1 3.17Å; Q191-D195 WeakPolarHBondContact O-CB 3.41Å; Q191-D195 VanDerWaalsContact O-CG 3.31Å; Q191-D195 PolarHBondContact O-N 3.31Å; D195-N198 PolarHBondContact O-N 3.28Å; D195-R199 VanDerWaalsContact O-CG 3.31Å; D195-R199 WeakPolarHBondContact O-CG 3.13Å; D195-R199 PolarHBondContact O-N 2.97Å; D195-R199 VanDerWaalsContact O-N 3.11Å
196T86.2Confident82.6Confident13 Ų1331 Ų318%0.0816%0.16CC..Hα-helixtrans-69.7-42.6179.1-54.80000111.6L164 E167 F168 N192 Y193 I194 N198 R199 I200L164-T196 HydrophobicContact CB-CG2 4.2Å; E167-T196 HydrophobicContact CB-CG2 4.14Å; E167-T196 HydrophobicContact CG-CG2 4.39Å; F168-T196 HydrophobicContact CE2-CG2 3.57Å; F168-T196 HydrophobicContact CZ-CG2 3.81Å; N192-T196 WeakPolarHBondContact O-CB 3.38Å; N192-T196 PolarHBondContact O-N 2.88Å; N192-T196 PolarHBondContact O-OG1 3.33Å; Y193-T196 PolarHBondContact O-N 3.17Å; I194-T196 PolarHBondContact O-N 3.05Å; T196-N198 VanDerWaalsContact C-N 3.32Å; T196-N198 PolarHBondContact O-N 3.22Å; T196-R199 PolarHBondContact O-N 3.45Å; T196-I200 HydrophobicContact CG2-CD1 4.35Å; T196-I200 PolarHBondContact O-N 2.95Å
197A90.1Very high81.3Confident0 Ų032 Ų320%017%0.167CC..Hα-helixtrans-62.8-40.5176.400000111.2F41 W44 L116 F168 Y193 I194 R199 I200 C201F41-A197 HydrophobicContact CE2-CB 4.01Å; W44-A197 HydrophobicContact CH2-CB 3.96Å; W44-A197 HydrophobicContact CZ3-CB 3.86Å; L116-A197 HydrophobicContact CD1-CB 4.2Å; F168-A197 HydrophobicContact CZ-CB 4.15Å; Y193-A197 WeakPolarHBondContact O-CB 3.31Å; Y193-A197 PolarHBondContact O-N 3.05Å; I194-A197 PolarHBondContact O-N 3.2Å; A197-R199 VanDerWaalsContact C-N 3.32Å; A197-R199 PolarHBondContact O-N 3.06Å; A197-I200 PolarHBondContact O-N 2.96Å; A197-C201 WeakPolarHBondContact O-CB 3.36Å; A197-C201 PolarHBondContact O-N 3.3Å; A197-C201 PolarHBondContact O-SG 3.15Å
198N86.7Confident80.2Confident48 Ų4832.6 Ų32.626%0.25717%0.172SC..Hα-helixtrans-60.7-40.5174.9-174.292.9000112.1F41 K45 I194 D195 T196 C201 V202F41-N198 HydrophobicContact CE1-CB 4.27Å; F41-N198 HydrophobicContact CZ-CB 3.82Å; K45-N198 PolarHBondContact NZ-OD1 3.21Å; I194-N198 VanDerWaalsContact O-CB 3.29Å; I194-N198 WeakPolarHBondContact O-CB 3.34Å; I194-N198 PolarHBondContact O-N 2.86Å; D195-N198 PolarHBondContact O-N 3.28Å; T196-N198 VanDerWaalsContact C-N 3.32Å; T196-N198 PolarHBondContact O-N 3.22Å; N198-C201 PolarHBondContact O-N 2.86Å; N198-V202 WeakPolarHBondContact O-CB 3.39Å; N198-V202 VanDerWaalsContact O-CG2 3.24Å; N198-V202 WeakPolarHBondContact O-CG2 3.33Å; N198-V202 PolarHBondContact O-N 3.18Å
199R83.6Confident79.4Confident44 Ų4436.7 Ų36.717%0.16620%0.196CC..Hα-helixtrans-66.1-46.2176.6-69.9171.870.5-1481.4111.9D195 T196 A197 C201 V202 I203 I391 E394 F446D195-R199 VanDerWaalsContact O-CG 3.31Å; D195-R199 WeakPolarHBondContact O-CG 3.13Å; D195-R199 PolarHBondContact O-N 2.97Å; D195-R199 VanDerWaalsContact O-N 3.11Å; T196-R199 PolarHBondContact O-N 3.45Å; A197-R199 VanDerWaalsContact C-N 3.32Å; A197-R199 PolarHBondContact O-N 3.06Å; R199-C201 VanDerWaalsContact C-N 3.3Å; R199-C201 PolarHBondContact O-N 3.35Å; R199-V202 PolarHBondContact O-N 3.49Å; R199-I203 WeakPolarHBondContact O-CG1 3.36Å; R199-I203 PolarHBondContact O-N 3.22Å; R199-I391 VanDerWaalsContact NH2-CG1 3.31Å; R199-E394 IonicContact NH2-OE2 2.86Å; R199-E394 PolarHBondContact NH2-OE2 2.94Å; R199-F446 VanDerWaalsContact NH1-CE2 3.26Å; R199-F446 VanDerWaalsContact NH1-CZ 3.26Å
200I86.1Confident78.4Confident0 Ų037.5 Ų37.50%020%0.2CC..Hα-helixtrans-53.8-49.9173.6-75.4168.9000110.4F119 L120 I161 L164 F168 T196 A197 V202 I203 H204F119-I200 HydrophobicContact CE1-CG2 3.65Å; F119-I200 HydrophobicContact CZ-CG2 3.57Å; L120-I200 HydrophobicContact CD2-CD1 4.14Å; I161-I200 HydrophobicContact CD1-CB 4.48Å; I161-I200 HydrophobicContact CD1-CG2 3.55Å; L164-I200 HydrophobicContact CB-CD1 4.05Å; L164-I200 HydrophobicContact CB-CG1 4.02Å; L164-I200 HydrophobicContact CD1-CG1 3.93Å; F168-I200 HydrophobicContact CE2-CD1 3.78Å; T196-I200 HydrophobicContact CG2-CD1 4.35Å; T196-I200 PolarHBondContact O-N 2.95Å; A197-I200 PolarHBondContact O-N 2.96Å; I200-V202 PolarHBondContact O-N 3.12Å; I200-I203 PolarHBondContact O-N 2.77Å; I200-H204 WeakPolarHBondContact O-CB 3.21Å; I200-H204 PolarHBondContact O-N 2.82Å
201C84.3Confident77.5Confident7 Ų741.5 Ų41.55%0.04722%0.221CC..Hα-helixtrans-65.6-37.7-179.4-63.50000112.6Y38 F41 A197 N198 R199 S205Y38-C201 HydrophobicContact CD1-CB 4.04Å; Y38-C201 HydrophobicContact CE1-CB 3.9Å; Y38-C201 VanDerWaalsContact CE1-SG 3.55Å; F41-C201 HydrophobicContact CD1-CB 4.05Å; F41-C201 HydrophobicContact CD2-CB 4.4Å; F41-C201 WeakPolarHBondContact CD2-SG 3.36Å; F41-C201 HydrophobicContact CE1-CB 4.09Å; F41-C201 HydrophobicContact CE2-CB 4.43Å; F41-C201 VanDerWaalsContact CE2-SG 3.58Å; F41-C201 HydrophobicContact CG-CB 4.23Å; F41-C201 HydrophobicContact CZ-CB 4.3Å; A197-C201 WeakPolarHBondContact O-CB 3.36Å; A197-C201 PolarHBondContact O-N 3.3Å; A197-C201 PolarHBondContact O-SG 3.15Å; N198-C201 PolarHBondContact O-N 2.86Å; R199-C201 VanDerWaalsContact C-N 3.3Å; R199-C201 PolarHBondContact O-N 3.35Å; C201-S205 WeakPolarHBondContact O-CA 3.33Å; C201-S205 WeakPolarHBondContact O-CB 3.42Å; C201-S205 PolarHBondContact O-N 3.28Å; C201-S205 PolarHBondContact O-OG 3.24Å
202V80.5Confident77Confident67 Ų6739.8 Ų39.841%0.40621%0.214SC..Hα-helixtrans-65.6-41.9176.6167.80000111.8N198 R199 I200 S205N198-V202 WeakPolarHBondContact O-CB 3.39Å; N198-V202 VanDerWaalsContact O-CG2 3.24Å; N198-V202 WeakPolarHBondContact O-CG2 3.33Å; N198-V202 PolarHBondContact O-N 3.18Å; R199-V202 PolarHBondContact O-N 3.49Å; I200-V202 PolarHBondContact O-N 3.12Å; V202-S205 PolarHBondContact O-OG 2.88Å
203I72.1Confident76.1Confident26 Ų2639.7 Ų39.713%0.13322%0.217CC..Hα-helixtrans-68.9-41.3-179.8-64.9165.3000110.7I161 L164 R199 I200 V390I161-I203 HydrophobicContact CG2-CB 3.76Å; I161-I203 HydrophobicContact CG2-CD1 4.14Å; I161-I203 HydrophobicContact CG2-CG2 3.39Å; L164-I203 HydrophobicContact CD1-CD1 4.37Å; R199-I203 WeakPolarHBondContact O-CG1 3.36Å; R199-I203 PolarHBondContact O-N 3.22Å; I200-I203 PolarHBondContact O-N 2.77Å; I203-V390 HydrophobicContact CD1-CG1 4.04Å
204H70.4Confident74.7Confident0 Ų046.1 Ų46.10%025%0.249CC..Hα-helixtrans-95.8-19.4-170.4-169.5-62.6000114.4V34 Y38 V154 S157 I161 I200 Q206 S207 S208V34-H204 VanDerWaalsContact CG1-CE1 3.42Å; V34-H204 WeakPolarHBondContact CG1-CE1 3.38Å; Y38-H204 AromaticContact CE2-ND1 3.38Å; Y38-H204 WeakPolarHBondContact CE2-ND1 3.35Å; Y38-H204 AromaticContact CZ-CG 3.94Å; Y38-H204 AromaticContact CZ-ND1 3.49Å; Y38-H204 WeakPolarHBondContact OH-CB 3.29Å; Y38-H204 PolarHBondContact OH-ND1 3.4Å; V154-H204 PolarHBondContact O-NE2 3.36Å; S157-H204 WeakPolarHBondContact OG-CA 3.39Å; S157-H204 PolarHBondContact OG-CD2 2.96Å; S157-H204 VanDerWaalsContact OG-CD2 3.3Å; I161-H204 HydrophobicContact CD1-CB 4.05Å; I200-H204 WeakPolarHBondContact O-CB 3.21Å; I200-H204 PolarHBondContact O-N 2.82Å; H204-Q206 PolarHBondContact O-N 3.1Å; H204-S207 PolarHBondContact O-N 3.19Å; H204-S207 VanDerWaalsContact O-N 3.15Å; H204-S207 PolarHBondContact O-OG 3.44Å; H204-S208 PolarHBondContact CE1-OG 3.27Å; H204-S208 VanDerWaalsContact CE1-OG 3.28Å; H204-S208 PolarHBondContact ND1-OG 3.24Å; H204-S208 PolarHBondContact O-N 3.35Å; H204-S208 PolarHBondContact O-OG 3.32Å
205S67Low73.7Confident57 Ų5754.2 Ų54.240%0.39929%0.286SS..Hα-helixtrans-59.8-29.4174.753.40000113C201 V202 S207 S208C201-S205 WeakPolarHBondContact O-CA 3.33Å; C201-S205 WeakPolarHBondContact O-CB 3.42Å; C201-S205 PolarHBondContact O-N 3.28Å; C201-S205 PolarHBondContact O-OG 3.24Å; V202-S205 PolarHBondContact O-OG 2.88Å; S205-S207 VanDerWaalsContact C-N 3.31Å; S205-S207 PolarHBondContact O-N 3.03Å; S205-S208 PolarHBondContact O-N 3.05Å
206Q64Low73Confident145 Ų14551.1 Ų51.168%0.67827%0.27SS*.THydrogen-bonded Turntrans-66.5-30.9178.7-63.1-176.6700113.1H204H204-Q206 PolarHBondContact O-N 3.1Å
207S63.8Low71.9Confident21 Ų2152.2 Ų52.215%0.14728%0.28CS..THydrogen-bonded Turntrans-88.3-4.3177.552.20000113.3V154 S157 H204 S205 F210V154-S207 WeakPolarHBondContact CG2-O 3.49Å; S157-S207 WeakPolarHBondContact CB-OG 3.41Å; S157-S207 PolarHBondContact OG-OG 3.07Å; H204-S207 PolarHBondContact O-N 3.19Å; H204-S207 VanDerWaalsContact O-N 3.15Å; H204-S207 PolarHBondContact O-OG 3.44Å; S205-S207 VanDerWaalsContact C-N 3.31Å; S205-S207 PolarHBondContact O-N 3.03Å; S207-F210 VanDerWaalsContact O-CE1 3.32Å; S207-F210 WeakPolarHBondContact O-CE1 3.36Å
208S58.7Low70.8Confident13 Ų1361.2 Ų61.29%0.09132%0.322CS..  trans-106.417.8-170.4-51.80000114.1Y38 H204 S205 F210Y38-S208 VanDerWaalsContact CE2-OG 3.31Å; Y38-S208 WeakPolarHBondContact CE2-OG 3.46Å; H204-S208 PolarHBondContact CE1-OG 3.27Å; H204-S208 VanDerWaalsContact CE1-OG 3.28Å; H204-S208 PolarHBondContact ND1-OG 3.24Å; H204-S208 PolarHBondContact O-N 3.35Å; H204-S208 PolarHBondContact O-OG 3.32Å; S205-S208 PolarHBondContact O-N 3.05Å; S208-F210 VanDerWaalsContact C-N 3.27Å; S208-F210 PolarHBondContact O-N 3.19Å
209N66.4Low70.4Confident153 Ų15364 Ų6482%0.81833%0.334SS*.  trans-86.759.6-175-166.926.5000112.5
210F67.3Low70.3Confident19 Ų1962.7 Ų62.78%0.08333%0.33CS..SBendtrans-139.1155.2177.553.8-94.2000111.8M31 K35 D150 V154 S207 S208 I212M31-F210 HydrophobicContact CB-CZ 4.38Å; M31-F210 HydrophobicContact CE-CD2 4.41Å; M31-F210 HydrophobicContact CE-CE1 4.04Å; M31-F210 HydrophobicContact CE-CE2 3.49Å; M31-F210 VanDerWaalsContact CE-CE2 3.49Å; M31-F210 HydrophobicContact CE-CZ 3.29Å; K35-F210 PolarHBondContact NZ-O 2.98Å; D150-F210 HydrophobicContact CB-CD1 3.99Å; D150-F210 HydrophobicContact CB-CG 4.27Å; V154-F210 HydrophobicContact CG2-CE1 3.34Å; V154-F210 HydrophobicContact CG2-CZ 3.59Å; S207-F210 VanDerWaalsContact O-CE1 3.32Å; S207-F210 WeakPolarHBondContact O-CE1 3.36Å; S208-F210 VanDerWaalsContact C-N 3.27Å; S208-F210 PolarHBondContact O-N 3.19Å; F210-I212 HydrophobicContact CD2-CB 3.79Å; F210-I212 HydrophobicContact CD2-CG2 3.9Å; F210-I212 HydrophobicContact CE2-CB 3.7Å; F210-I212 HydrophobicContact CE2-CD1 4.05Å; F210-I212 HydrophobicContact CE2-CG2 3.47Å; F210-I212 VanDerWaalsContact CE2-CG2 3.47Å; F210-I212 PolarHBondContact O-N 3.19Å
211D69.1Low70.2Confident84 Ų8465 Ų6545%0.44935%0.348SS..  trans-88.688.3-179.2-170.128.1000109.9K35 K145 M216K35-D211 IonicContact NZ-OD1 3.02Å; K145-D211 HydrophobicContact CD-CB 4.29Å; K145-D211 WeakPolarHBondContact CD-OD2 3.48Å; K145-D211 IonicContact NZ-OD2 2.91Å; K145-D211 PolarHBondContact NZ-OD2 3.03Å; D211-M216 VanDerWaalsContact O-CE 3.23Å; D211-M216 WeakPolarHBondContact O-CE 3.4Å
212I74.4Confident70.2Confident7 Ų765.1 Ų65.14%0.03635%0.349CS..  trans-106.7139.3172.1-166.8159.8000110.7L28 M31 A32 K35 I146 F210L28-I212 HydrophobicContact CB-CD1 3.99Å; L28-I212 HydrophobicContact CD2-CD1 4.01Å; L28-I212 HydrophobicContact CG-CD1 4.47Å; L28-I212 VanDerWaalsContact O-CD1 3.32Å; L28-I212 WeakPolarHBondContact O-CD1 3.35Å; M31-I212 HydrophobicContact CB-CD1 3.84Å; M31-I212 HydrophobicContact CE-CD1 4.23Å; A32-I212 HydrophobicContact CB-CG1 4.38Å; A32-I212 HydrophobicContact CB-CG2 4.28Å; K35-I212 HydrophobicContact CB-CG2 4.34Å; K35-I212 HydrophobicContact CD-CG2 3.58Å; I146-I212 HydrophobicContact CD1-CB 4.08Å; I146-I212 HydrophobicContact CD1-CD1 3.67Å; I146-I212 HydrophobicContact CD1-CG1 3.65Å; F210-I212 HydrophobicContact CD2-CB 3.79Å; F210-I212 HydrophobicContact CD2-CG2 3.9Å; F210-I212 HydrophobicContact CE2-CB 3.7Å; F210-I212 HydrophobicContact CE2-CD1 4.05Å; F210-I212 HydrophobicContact CE2-CG2 3.47Å; F210-I212 VanDerWaalsContact CE2-CG2 3.47Å; F210-I212 PolarHBondContact O-N 3.19Å
213C66.2Low70.4Confident50 Ų5063.9 Ų63.934%0.33834%0.34SS..  trans-141.2157.5165.275.80000109.9E215 M216C213-E215 PolarHBondContact O-N 3.22Å; C213-E215 VanDerWaalsContact O-N 3.14Å; C213-M216 HydrophobicContact CB-CE 4.27Å; C213-M216 WeakPolarHBondContact O-CB 3.37Å; C213-M216 WeakPolarHBondContact O-CG 3.25Å; C213-M216 PolarHBondContact O-N 2.97Å; C213-M216 VanDerWaalsContact SG-CE 3.57Å
214M61.3Low70.8Confident139 Ų13962.7 Ų62.769%0.68533%0.334SS*.G310 helixtrans-61.1-23.8-177.2-71.6-151.9-62.300114.1T29 M216 A217T29-M214 HydrophobicContact CG2-SD 4.34Å; M214-M216 PolarHBondContact O-N 2.98Å; M214-A217 PolarHBondContact O-N 3.11Å
215E65.4Low71.3Confident170 Ų17067.3 Ų67.379%0.79436%0.359SS*.G310 helixtrans-68.3-16.9-179.2-59.4177169.900112.7C213 A217C213-E215 PolarHBondContact O-N 3.22Å; C213-E215 VanDerWaalsContact O-N 3.14Å; E215-A217 PolarHBondContact O-N 3.38Å
216M68.9Low72Confident11 Ų1171.1 Ų71.15%0.05438%0.375CS..G310 helixtrans-73.7-5.7-179.3-60.2-178.6-169.800113.8P143 K145 I146 D211 C213 M214 E218 E219P143-M216 HydrophobicContact CB-CB 4.04Å; P143-M216 HydrophobicContact CB-SD 4.42Å; P143-M216 HydrophobicContact CG-CB 3.79Å; P143-M216 WeakPolarHBondContact CG-O 3.36Å; K145-M216 HydrophobicContact CD-CE 3.66Å; I146-M216 HydrophobicContact CD1-SD 3.98Å; I146-M216 HydrophobicContact CG1-SD 4.47Å; D211-M216 VanDerWaalsContact O-CE 3.23Å; D211-M216 WeakPolarHBondContact O-CE 3.4Å; C213-M216 HydrophobicContact CB-CE 4.27Å; C213-M216 WeakPolarHBondContact O-CB 3.37Å; C213-M216 WeakPolarHBondContact O-CG 3.25Å; C213-M216 PolarHBondContact O-N 2.97Å; C213-M216 VanDerWaalsContact SG-CE 3.57Å; M214-M216 PolarHBondContact O-N 2.98Å; M216-E218 PolarHBondContact O-N 2.91Å; M216-E219 PolarHBondContact O-N 2.89Å
217A62.7Low72.9Confident36 Ų3665.4 Ų65.430%0.29835%0.349SS..G310 helixtrans-62.1-27.6178.400000113.5T25 M214 E215 E219T25-A217 HydrophobicContact CG2-CB 3.67Å; M214-A217 PolarHBondContact O-N 3.11Å; E215-A217 PolarHBondContact O-N 3.38Å; A217-E219 PolarHBondContact O-N 3.12Å
218E68Low74.1Confident189 Ų18967.2 Ų67.288%0.88336%0.361SS*.G310 helixtrans-73.7-15.7179.9-62.2-170.6172.300113.3M216M216-E218 PolarHBondContact O-N 2.91Å
219E77.4Confident75.3Confident107 Ų10770 Ų7050%0.537%0.372SS..G310 helixtrans-87.8-9.5-178.7-61.4179.5-163.100112.9P143 M216 A217 A221P143-E219 HydrophobicContact CB-CB 4.2Å; P143-E219 WeakPolarHBondContact CB-OE2 3.44Å; P143-E219 HydrophobicContact CG-CB 4.13Å; M216-E219 PolarHBondContact O-N 2.89Å; A217-E219 PolarHBondContact O-N 3.12Å; E219-A221 PolarHBondContact O-N 2.97Å
220I82.3Confident76.3Confident16 Ų1667.1 Ų67.18%0.08236%0.357CS..  trans-72.6119.9-179.6-58.6160.4000109.9V24 T25 L28 Y141 P143V24-I220 HydrophobicContact CB-CD1 4.48Å; V24-I220 HydrophobicContact CB-CG2 4.39Å; V24-I220 HydrophobicContact CG1-CD1 3.83Å; V24-I220 HydrophobicContact CG1-CG1 4.22Å; V24-I220 HydrophobicContact CG1-CG2 4.02Å; T25-I220 VanDerWaalsContact OG1-CD1 3.28Å; T25-I220 WeakPolarHBondContact OG1-CD1 3.32Å; L28-I220 HydrophobicContact CD1-CD1 4.03Å; L28-I220 HydrophobicContact CD1-CG1 4.39Å; Y141-I220 WeakPolarHBondContact O-CA 3.43Å; P143-I220 HydrophobicContact CG-CG1 4.5Å
221A83.3Confident77.2Confident48 Ų4868.9 Ų68.940%0.39737%0.367SS..EExtended strand (participates in β ladder)trans-118.9142.5175.700000111.9Y141 E219Y141-A221 HydrophobicContact CD2-CB 4.22Å; Y141-A221 PolarHBondContact N-O 3.29Å; Y141-A221 PolarHBondContact O-N 3.24Å; E219-A221 PolarHBondContact O-N 2.97Å
222V84.9Confident78.1Confident10 Ų1064.9 Ų64.96%0.06135%0.346CS..EExtended strand (participates in β ladder)trans-116.1112.1175173.60000110.4Q17 L20 C21 I139Q17-V222 HydrophobicContact CB-CB 4.37Å; Q17-V222 HydrophobicContact CB-CG1 4.49Å; Q17-V222 HydrophobicContact CG-CB 4Å; Q17-V222 HydrophobicContact CG-CG1 3.91Å; Q17-V222 PolarHBondContact NE2-O 3.47Å; L20-V222 HydrophobicContact CB-CG2 4.19Å; L20-V222 HydrophobicContact CD2-CG1 3.93Å; L20-V222 HydrophobicContact CD2-CG2 3.94Å; L20-V222 HydrophobicContact CG-CG2 4.03Å; C21-V222 WeakPolarHBondContact SG-CG2 3.32Å; I139-V222 HydrophobicContact CG2-CG1 3.96Å; I139-V222 CarbonylContact O-C 3.55Å; I139-V222 WeakPolarHBondContact O-CA 3.41Å
223N84.9Confident78.9Confident40 Ų4066.8 Ų66.821%0.21435%0.354CS..  trans-87.5127.3170.7-179.18.5000110.5I139 Y141 D225I139-N223 WeakPolarHBondContact CA-O 3.24Å; I139-N223 WeakPolarHBondContact CG2-O 3.17Å; I139-N223 PolarHBondContact O-N 2.97Å; Y141-N223 HydrophobicContact CE2-CB 3.68Å; N223-D225 WeakPolarHBondContact OD1-CB 3.49Å; N223-D225 PolarHBondContact OD1-N 2.8Å; N223-D225 PolarHBondContact OD1-OD2 3Å
224S81.5Confident79.9Confident1 Ų169.4 Ų69.41%0.00736%0.36CS..  trans-135.916.1-178.240.50000111.3R13 D226 L227R13-S224 WeakPolarHBondContact CG-OG 3.48Å; R13-S224 PolarHBondContact NE-OG 3.23Å; S224-D226 VanDerWaalsContact C-N 3.26Å; S224-D226 PolarHBondContact O-N 3.48Å; S224-L227 PolarHBondContact O-N 3.16Å
225D80.6Confident81.3Confident97 Ų9763 Ų6352%0.51933%0.329SS..THydrogen-bonded Turntrans-61.3-34.6-176.9-77.1-45.5000112.5R13 N223R13-D225 IonicContact CZ-OD1 2.68Å; R13-D225 IonicContact NH1-OD1 3.91Å; R13-D225 PolarHBondContact NH1-OD1 3.48Å; R13-D225 VanDerWaalsContact NH2-CG 3.26Å; R13-D225 IonicContact NH2-OD1 3.77Å; R13-D225 PolarHBondContact NH2-OD1 3.43Å; R13-D225 IonicContact NH2-OD2 2.71Å; R13-D225 PolarHBondContact NH2-OD2 2.67Å; N223-D225 WeakPolarHBondContact OD1-CB 3.49Å; N223-D225 PolarHBondContact OD1-N 2.8Å; N223-D225 PolarHBondContact OD1-OD2 3Å
226D80.9Confident82.6Confident138 Ų13854.9 Ų54.974%0.73829%0.291SS*.THydrogen-bonded Turntrans-955.1-176.3-60.6-44.7000114S224S224-D226 VanDerWaalsContact C-N 3.26Å; S224-D226 PolarHBondContact O-N 3.48Å
227L83.7Confident83.6Confident24 Ų2458 Ų5813%0.12631%0.308CS..  trans-95.6138.5-177-63.8176.2000112.7L16 I139 S224 M232 M235 L520L16-L227 HydrophobicContact CD2-CD1 3.65Å; I139-L227 HydrophobicContact CD1-CD1 3.99Å; I139-L227 HydrophobicContact CD1-CD2 4.17Å; I139-L227 HydrophobicContact CG1-CD1 4.44Å; S224-L227 PolarHBondContact O-N 3.16Å; L227-M232 HydrophobicContact CB-CG 3.69Å; L227-M232 HydrophobicContact CB-SD 4.47Å; L227-M232 HydrophobicContact CD1-CG 4.18Å; L227-M235 HydrophobicContact CD1-SD 3.87Å; L227-M235 HydrophobicContact CD2-SD 4.37Å; L227-L520 HydrophobicContact CD2-CD2 4.43Å
228C87.3Confident84.9Confident59 Ų5957.2 Ų57.240%0.39930%0.298SS..  trans-78.4160.917287.20000112.1N230 D231 M232C228-N230 VanDerWaalsContact C-N 3.27Å; C228-N230 PolarHBondContact O-N 2.77Å; C228-D231 PolarHBondContact O-N 2.9Å; C228-D231 VanDerWaalsContact O-N 3.17Å; C228-D231 PolarHBondContact SG-N 3.33Å; C228-D231 VanDerWaalsContact SG-N 3.41Å; C228-D231 PolarHBondContact SG-OD2 3.28Å; C228-M232 WeakPolarHBondContact O-CG 3.43Å; C228-M232 PolarHBondContact O-N 3.32Å
229E85.7Confident86Confident71 Ų7148.2 Ų48.233%0.33226%0.256SS..Hα-helixtrans-54-43.1179.5179.1173.6155.800112.7H8 Y12 M232 Q233H8-E229 IonicContact CE1-OE1 3.49Å; H8-E229 PolarHBondContact CE1-OE1 3.11Å; H8-E229 IonicContact ND1-OE1 3.36Å; H8-E229 PolarHBondContact ND1-OE1 3.22Å; H8-E229 IonicContact ND1-OE2 3.96Å; Y12-E229 HydrophobicContact CD1-CG 4.19Å; Y12-E229 HydrophobicContact CD2-CG 3.54Å; Y12-E229 HydrophobicContact CE1-CG 4.13Å; Y12-E229 HydrophobicContact CE2-CG 3.47Å; Y12-E229 VanDerWaalsContact CE2-CG 3.47Å; Y12-E229 WeakPolarHBondContact CE2-OE1 3.36Å; Y12-E229 HydrophobicContact CG-CG 3.88Å; Y12-E229 PolarHBondContact OH-OE1 3.13Å; E229-M232 PolarHBondContact O-N 3.46Å; E229-Q233 WeakPolarHBondContact O-CB 3.27Å; E229-Q233 PolarHBondContact O-N 3.26Å
230N86.8Confident86.7Confident93 Ų9347.8 Ų47.850%0.49725%0.252SS..Hα-helixtrans-66.3-39.6-178.9-175.354.1000112.1C228 Q233 K234C228-N230 VanDerWaalsContact C-N 3.27Å; C228-N230 PolarHBondContact O-N 2.77Å; N230-Q233 PolarHBondContact O-N 3.46Å; N230-K234 WeakPolarHBondContact ND2-CE 3.39Å; N230-K234 PolarHBondContact ND2-NZ 2.97Å; N230-K234 WeakPolarHBondContact O-CG 3.4Å; N230-K234 PolarHBondContact O-N 3.26Å
231D87Confident87.1Confident57 Ų5750.3 Ų50.331%0.30527%0.266SS..Hα-helixtrans-70.8-43.6178.5-61.6-26.7000110.5C228 Q233 K234 M235C228-D231 PolarHBondContact O-N 2.9Å; C228-D231 VanDerWaalsContact O-N 3.17Å; C228-D231 PolarHBondContact SG-N 3.33Å; C228-D231 VanDerWaalsContact SG-N 3.41Å; C228-D231 PolarHBondContact SG-OD2 3.28Å; D231-Q233 VanDerWaalsContact C-N 3.26Å; D231-Q233 PolarHBondContact O-N 3.34Å; D231-K234 PolarHBondContact O-N 3.45Å; D231-M235 WeakPolarHBondContact O-CB 3.42Å; D231-M235 VanDerWaalsContact O-CG 3.23Å; D231-M235 WeakPolarHBondContact O-CG 3.36Å; D231-M235 PolarHBondContact O-N 3.3Å
232M88.2Confident87.5Confident0 Ų048 Ų480%025%0.247CC..Hα-helixtrans-57.4-40.8174.6-70.1-169.4-81.600112.4F9 R13 L16 L227 C228 E229 T236F9-M232 HydrophobicContact CD2-CE 3.95Å; F9-M232 HydrophobicContact CE1-CE 4.37Å; F9-M232 HydrophobicContact CE2-CE 3.39Å; F9-M232 HydrophobicContact CZ-CE 3.64Å; R13-M232 VanDerWaalsContact CA-SD 3.58Å; R13-M232 HydrophobicContact CB-SD 4Å; R13-M232 HydrophobicContact CG-SD 4.35Å; L16-M232 HydrophobicContact CB-CB 4.45Å; L16-M232 HydrophobicContact CD2-CB 4.11Å; L16-M232 HydrophobicContact CD2-CG 3.79Å; L227-M232 HydrophobicContact CB-CG 3.69Å; L227-M232 HydrophobicContact CB-SD 4.47Å; L227-M232 HydrophobicContact CD1-CG 4.18Å; C228-M232 WeakPolarHBondContact O-CG 3.43Å; C228-M232 PolarHBondContact O-N 3.32Å; E229-M232 PolarHBondContact O-N 3.46Å; M232-T236 VanDerWaalsContact O-CB 3.32Å; M232-T236 WeakPolarHBondContact O-CB 3.44Å; M232-T236 PolarHBondContact O-N 3.39Å; M232-T236 PolarHBondContact O-OG1 3.47Å
233Q89.4Confident87.8Confident46 Ų4650.2 Ų50.222%0.21526%0.258CS..Hα-helixtrans-67.2-47.1177.6-174.755.948.400111.6Y12 E229 N230 D231 M235 T236 D237Y12-Q233 HydrophobicContact CD1-CB 4.06Å; Y12-Q233 HydrophobicContact CE1-CB 4.11Å; Y12-Q233 HydrophobicContact CE1-CG 4.2Å; E229-Q233 WeakPolarHBondContact O-CB 3.27Å; E229-Q233 PolarHBondContact O-N 3.26Å; N230-Q233 PolarHBondContact O-N 3.46Å; D231-Q233 VanDerWaalsContact C-N 3.26Å; D231-Q233 PolarHBondContact O-N 3.34Å; Q233-M235 PolarHBondContact O-N 3Å; Q233-T236 WeakPolarHBondContact O-CB 3.2Å; Q233-T236 PolarHBondContact O-N 3.38Å; Q233-D237 PolarHBondContact NE2-OD1 3.43Å; Q233-D237 PolarHBondContact NE2-OD2 3.24Å; Q233-D237 PolarHBondContact O-N 2.86Å
234K89Confident88.1Confident105 Ų10555.2 Ų55.246%0.45728%0.278SS..Hα-helixtrans-58.6-46.6176.1-74.7173.4-179.1176.30112.4N230 D231 T236 D237 Q238N230-K234 WeakPolarHBondContact ND2-CE 3.39Å; N230-K234 PolarHBondContact ND2-NZ 2.97Å; N230-K234 WeakPolarHBondContact O-CG 3.4Å; N230-K234 PolarHBondContact O-N 3.26Å; D231-K234 PolarHBondContact O-N 3.45Å; K234-T236 VanDerWaalsContact C-N 3.33Å; K234-T236 PolarHBondContact O-N 3Å; K234-D237 PolarHBondContact O-N 2.92Å; K234-Q238 WeakPolarHBondContact O-CB 3.32Å; K234-Q238 PolarHBondContact O-N 2.68Å
235M89.8Confident88.4Confident5 Ų555.4 Ų55.43%0.02528%0.279CS..Hα-helixtrans-62.9-42.1178-66.8178.486.300111L16 I139 L227 D231 Q233 D237 Q238 I239 F519 L520L16-M235 HydrophobicContact CD1-CB 3.69Å; L16-M235 HydrophobicContact CD2-SD 4.43Å; I139-M235 HydrophobicContact CD1-CE 3.41Å; I139-M235 VanDerWaalsContact CD1-CE 3.41Å; I139-M235 HydrophobicContact CD1-SD 4.15Å; L227-M235 HydrophobicContact CD1-SD 3.87Å; L227-M235 HydrophobicContact CD2-SD 4.37Å; D231-M235 WeakPolarHBondContact O-CB 3.42Å; D231-M235 VanDerWaalsContact O-CG 3.23Å; D231-M235 WeakPolarHBondContact O-CG 3.36Å; D231-M235 PolarHBondContact O-N 3.3Å; Q233-M235 PolarHBondContact O-N 3Å; M235-D237 VanDerWaalsContact C-N 3.34Å; M235-D237 PolarHBondContact O-N 3.25Å; M235-Q238 PolarHBondContact O-N 2.87Å; M235-I239 WeakPolarHBondContact O-CG1 3.16Å; M235-I239 PolarHBondContact O-N 3.17Å; M235-F519 HydrophobicContact CB-CE2 4.46Å; M235-F519 HydrophobicContact CE-CD1 3.64Å; M235-F519 HydrophobicContact CE-CD2 4.32Å; M235-F519 HydrophobicContact CE-CE1 3.14Å; M235-F519 HydrophobicContact CE-CE2 3.87Å; M235-F519 HydrophobicContact CE-CG 4.21Å; M235-F519 HydrophobicContact CE-CZ 3.26Å; M235-L520 HydrophobicContact CE-CD2 3.71Å; M235-L520 HydrophobicContact CE-CG 4.15Å; M235-L520 HydrophobicContact SD-CD2 3.71Å
236T91.5Very high89Confident0 Ų050.8 Ų50.80%025%0.254CS..Hα-helixtrans-59.7-45.2175.3-60.90000111.4R15 L16 T19 M232 Q233 K234 I239 K240R15-T236 HydrophobicContact CB-CG2 4.46Å; L16-T236 WeakPolarHBondContact CA-OG1 3.32Å; T19-T236 HydrophobicContact CG2-CG2 4.49Å; M232-T236 VanDerWaalsContact O-CB 3.32Å; M232-T236 WeakPolarHBondContact O-CB 3.44Å; M232-T236 PolarHBondContact O-N 3.39Å; M232-T236 PolarHBondContact O-OG1 3.47Å; Q233-T236 WeakPolarHBondContact O-CB 3.2Å; Q233-T236 PolarHBondContact O-N 3.38Å; K234-T236 VanDerWaalsContact C-N 3.33Å; K234-T236 PolarHBondContact O-N 3Å; T236-I239 PolarHBondContact O-N 3.44Å; T236-K240 HydrophobicContact CG2-CD 4.41Å; T236-K240 WeakPolarHBondContact O-CG 3.43Å; T236-K240 PolarHBondContact O-N 2.71Å
237D90.6Very high89.6Confident76 Ų7648.2 Ų48.241%0.40624%0.238SC..Hα-helixtrans-69.2-36.4-179.9-66.8-26.5000111.8Q233 K234 M235 K240 L241Q233-D237 PolarHBondContact NE2-OD1 3.43Å; Q233-D237 PolarHBondContact NE2-OD2 3.24Å; Q233-D237 PolarHBondContact O-N 2.86Å; K234-D237 PolarHBondContact O-N 2.92Å; M235-D237 VanDerWaalsContact C-N 3.34Å; M235-D237 PolarHBondContact O-N 3.25Å; D237-K240 PolarHBondContact O-N 3.44Å; D237-L241 WeakPolarHBondContact O-CB 3.45Å; D237-L241 PolarHBondContact O-N 3.33Å
238Q89.6Confident90Very high19 Ų1949.5 Ų49.59%0.08925%0.246CC..Hα-helixtrans-63.5-47.2173.1-176.7174.7-3.200111.8K234 M235 K240 L241 L242 M517 A518K234-Q238 WeakPolarHBondContact O-CB 3.32Å; K234-Q238 PolarHBondContact O-N 2.68Å; M235-Q238 PolarHBondContact O-N 2.87Å; Q238-K240 VanDerWaalsContact C-N 3.33Å; Q238-K240 PolarHBondContact O-N 2.99Å; Q238-L241 WeakPolarHBondContact O-CB 3.49Å; Q238-L241 PolarHBondContact O-N 2.74Å; Q238-L241 VanDerWaalsContact O-N 3.16Å; Q238-L242 HydrophobicContact CG-CD1 4.32Å; Q238-L242 WeakPolarHBondContact O-CG 3.32Å; Q238-L242 PolarHBondContact O-N 3.36Å; Q238-M517 HydrophobicContact CG-CE 3.92Å; Q238-M517 PolarHBondContact NE2-O 3.21Å; Q238-A518 PolarHBondContact NE2-O 3.29Å
239I91.8Very high90.3Very high1 Ų153.3 Ų53.31%0.00526%0.258CS..Hα-helixtrans-62.7-40.8177.1-64.8-62000111.1T19 L20 Y23 V133 M235 T236 L241 L242 D243 F519T19-I239 HydrophobicContact CG2-CB 3.98Å; T19-I239 HydrophobicContact CG2-CG2 3.64Å; L20-I239 HydrophobicContact CD1-CD1 3.65Å; L20-I239 HydrophobicContact CD1-CG1 3.94Å; Y23-I239 HydrophobicContact CD1-CD1 4.27Å; Y23-I239 HydrophobicContact CD2-CG2 3.94Å; Y23-I239 HydrophobicContact CG-CD1 4.46Å; Y23-I239 HydrophobicContact CG-CG2 3.79Å; V133-I239 HydrophobicContact CG1-CD1 4.27Å; V133-I239 HydrophobicContact CG2-CD1 3.72Å; M235-I239 WeakPolarHBondContact O-CG1 3.16Å; M235-I239 PolarHBondContact O-N 3.17Å; T236-I239 PolarHBondContact O-N 3.44Å; I239-L241 VanDerWaalsContact C-N 3.28Å; I239-L241 PolarHBondContact O-N 3.41Å; I239-L242 HydrophobicContact CD1-CD1 4.19Å; I239-L242 PolarHBondContact O-N 2.79Å; I239-D243 WeakPolarHBondContact O-CB 3.22Å; I239-D243 PolarHBondContact O-N 3.36Å; I239-F519 HydrophobicContact CD1-CD2 4.23Å; I239-F519 HydrophobicContact CD1-CE2 3.41Å; I239-F519 VanDerWaalsContact CD1-CE2 3.41Å; I239-F519 HydrophobicContact CD1-CZ 3.97Å; I239-F519 HydrophobicContact CG1-CE2 3.76Å; I239-F519 HydrophobicContact CG1-CZ 4.23Å
240K91.9Very high90.6Very high98 Ų9851.7 Ų51.743%0.42625%0.251SS..Hα-helixtrans-61.5-37.8175-74.3173.5-175.9167.40112.6T19 T236 D237 Q238 K244T19-K240 HydrophobicContact CG2-CG 4.01Å; T236-K240 HydrophobicContact CG2-CD 4.41Å; T236-K240 WeakPolarHBondContact O-CG 3.43Å; T236-K240 PolarHBondContact O-N 2.71Å; D237-K240 PolarHBondContact O-N 3.44Å; Q238-K240 VanDerWaalsContact C-N 3.33Å; Q238-K240 PolarHBondContact O-N 2.99Å; K240-K244 VanDerWaalsContact O-CB 3.3Å; K240-K244 WeakPolarHBondContact O-CB 3.41Å; K240-K244 PolarHBondContact O-N 3.16Å
241L89.8Confident90.7Very high69 Ų6947.6 Ų47.636%0.36123%0.229SC..Hα-helixtrans-65.8-45.8174.9179.461.8000110.8D237 Q238 I239 D243 K244 I245 I514D237-L241 WeakPolarHBondContact O-CB 3.45Å; D237-L241 PolarHBondContact O-N 3.33Å; Q238-L241 WeakPolarHBondContact O-CB 3.49Å; Q238-L241 PolarHBondContact O-N 2.74Å; Q238-L241 VanDerWaalsContact O-N 3.16Å; I239-L241 VanDerWaalsContact C-N 3.28Å; I239-L241 PolarHBondContact O-N 3.41Å; L241-D243 PolarHBondContact O-N 3.37Å; L241-K244 PolarHBondContact O-N 3.35Å; L241-I245 HydrophobicContact CD1-CD1 4.19Å; L241-I245 HydrophobicContact CD1-CG1 4.46Å; L241-I245 HydrophobicContact CG-CD1 4.03Å; L241-I245 VanDerWaalsContact O-CG1 3.28Å; L241-I245 WeakPolarHBondContact O-CG1 3.3Å; L241-I245 PolarHBondContact O-N 2.88Å; L241-I514 HydrophobicContact CD2-CD1 4.16Å; L241-I514 HydrophobicContact CD2-CG1 4.31Å; L241-I514 HydrophobicContact CD2-CG2 3.87Å; L241-I514 HydrophobicContact CG-CG2 4.16Å
242L91.7Very high91Very high0 Ų045.5 Ų45.50%022%0.217CC..Hα-helixtrans-61.4-42.4176.9-70.5174.6000112.3Y23 V133 Q238 I239 I245 R246 I514 L515Y23-L242 HydrophobicContact CE2-CB 3.75Å; V133-L242 HydrophobicContact CG2-CD1 3.76Å; Q238-L242 HydrophobicContact CG-CD1 4.32Å; Q238-L242 WeakPolarHBondContact O-CG 3.32Å; Q238-L242 PolarHBondContact O-N 3.36Å; I239-L242 HydrophobicContact CD1-CD1 4.19Å; I239-L242 PolarHBondContact O-N 2.79Å; L242-I245 PolarHBondContact O-N 2.89Å; L242-R246 WeakPolarHBondContact O-CB 3.47Å; L242-R246 PolarHBondContact O-N 2.87Å; L242-I514 HydrophobicContact CD2-CG2 4.01Å; L242-L515 HydrophobicContact CD2-CD2 3.79Å
243D92.4Very high91.3Very high56 Ų5646.4 Ų46.430%0.29922%0.221SC..Hα-helixtrans-63.3-45.3175.6-176.557.1000111.3Y23 I239 L241 I245 R246 M247Y23-D243 HydrophobicContact CD2-CB 4.18Å; I239-D243 WeakPolarHBondContact O-CB 3.22Å; I239-D243 PolarHBondContact O-N 3.36Å; L241-D243 PolarHBondContact O-N 3.37Å; D243-I245 VanDerWaalsContact C-N 3.32Å; D243-I245 PolarHBondContact O-N 3.31Å; D243-R246 WeakPolarHBondContact O-CB 3.4Å; D243-R246 PolarHBondContact O-N 3.26Å; D243-M247 VanDerWaalsContact O-CG 3.31Å; D243-M247 WeakPolarHBondContact O-CG 3.25Å; D243-M247 PolarHBondContact O-N 3.19Å
244K91.1Very high91.3Very high144 Ų14445.2 Ų45.263%0.62622%0.216SC*.Hα-helixtrans-58.7-43.8175.5-175.7-176.8176.8-1710112.1K240 L241 M247 D248K240-K244 VanDerWaalsContact O-CB 3.3Å; K240-K244 WeakPolarHBondContact O-CB 3.41Å; K240-K244 PolarHBondContact O-N 3.16Å; L241-K244 PolarHBondContact O-N 3.35Å; K244-M247 PolarHBondContact O-N 3.47Å; K244-D248 WeakPolarHBondContact O-CB 3.49Å; K244-D248 PolarHBondContact O-N 2.94Å
245I88.7Confident91.4Very high6 Ų641.7 Ų41.73%0.03120%0.201CC..Hα-helixtrans-63.6-45.2176.9-72.6169.5000110.4L241 L242 D243 M247 D248 F251 I514 L515L241-I245 HydrophobicContact CD1-CD1 4.19Å; L241-I245 HydrophobicContact CD1-CG1 4.46Å; L241-I245 HydrophobicContact CG-CD1 4.03Å; L241-I245 VanDerWaalsContact O-CG1 3.28Å; L241-I245 WeakPolarHBondContact O-CG1 3.3Å; L241-I245 PolarHBondContact O-N 2.88Å; L242-I245 PolarHBondContact O-N 2.89Å; D243-I245 VanDerWaalsContact C-N 3.32Å; D243-I245 PolarHBondContact O-N 3.31Å; I245-M247 PolarHBondContact O-N 3.41Å; I245-D248 PolarHBondContact O-N 3.43Å; I245-D248 VanDerWaalsContact O-N 3.16Å; I245-F251 HydrophobicContact CB-CD1 4.47Å; I245-F251 HydrophobicContact CG2-CD1 3.26Å; I245-F251 HydrophobicContact CG2-CE1 3.2Å; I245-F251 HydrophobicContact CG2-CG 3.96Å; I245-F251 HydrophobicContact CG2-CZ 3.92Å; I245-F251 WeakPolarHBondContact O-CD1 3.03Å; I245-I514 HydrophobicContact CD1-CB 4.1Å; I245-I514 HydrophobicContact CD1-CD1 3.98Å; I245-I514 HydrophobicContact CD1-CG2 3.48Å; I245-I514 VanDerWaalsContact CD1-CG2 3.48Å; I245-L515 HydrophobicContact CG2-CD2 4.48Å
246R92.6Very high91.5Very high0 Ų041.6 Ų41.60%020%0.2CC..Hα-helixtrans-58.5-37178.7179.5-169-74.7177.1-12112.7Y23 T27 K125 V128 T129 L242 D243 R252Y23-R246 VanDerWaalsContact CE1-NH2 3.33Å; Y23-R246 VanDerWaalsContact CE2-NH2 3.33Å; Y23-R246 VanDerWaalsContact CZ-CZ 3.46Å; Y23-R246 PolarHBondContact O-NH1 3.4Å; Y23-R246 VanDerWaalsContact O-NH1 3.08Å; Y23-R246 PolarHBondContact OH-NH2 3.19Å; T27-R246 PolarHBondContact OG1-NH2 3.44Å; K125-R246 HydrophobicContact CB-CG 4.13Å; K125-R246 HydrophobicContact CG-CG 4.34Å; V128-R246 HydrophobicContact CG2-CB 4.21Å; V128-R246 HydrophobicContact CG2-CG 4.14Å; T129-R246 PolarHBondContact OG1-NE 3.41Å; T129-R246 VanDerWaalsContact OG1-NE 3.11Å; T129-R246 PolarHBondContact OG1-NH2 3Å; L242-R246 WeakPolarHBondContact O-CB 3.47Å; L242-R246 PolarHBondContact O-N 2.87Å; D243-R246 WeakPolarHBondContact O-CB 3.4Å; D243-R246 PolarHBondContact O-N 3.26Å; R246-R252 WeakPolarHBondContact O-CD 3.45Å
247M93.6Very high91.4Very high83 Ų8341.6 Ų41.641%0.40920%0.2SC..THydrogen-bonded Turntrans-88.6-5.3-178.6-60.1-61.8173.400113.8Y30 D243 K244 I245 E249Y30-M247 WeakPolarHBondContact OH-CE 3.46Å; D243-M247 VanDerWaalsContact O-CG 3.31Å; D243-M247 WeakPolarHBondContact O-CG 3.25Å; D243-M247 PolarHBondContact O-N 3.19Å; K244-M247 PolarHBondContact O-N 3.47Å; I245-M247 PolarHBondContact O-N 3.41Å; M247-E249 PolarHBondContact O-N 2.91Å
248D92.2Very high91.1Very high52 Ų5240.2 Ų40.228%0.27819%0.191SC..  trans-81.8108.1179.6-171.3-34.1000110K244 I245 D250 F251 R252K244-D248 WeakPolarHBondContact O-CB 3.49Å; K244-D248 PolarHBondContact O-N 2.94Å; I245-D248 PolarHBondContact O-N 3.43Å; I245-D248 VanDerWaalsContact O-N 3.16Å; D248-D250 VanDerWaalsContact C-N 3.31Å; D248-D250 PolarHBondContact O-N 2.83Å; D248-D250 WeakPolarHBondContact OD1-CB 3.21Å; D248-D250 PolarHBondContact OD1-N 3.01Å; D248-F251 HydrophobicContact CB-CB 3.77Å; D248-F251 WeakPolarHBondContact O-CB 3.44Å; D248-F251 PolarHBondContact O-N 3.32Å; D248-F251 PolarHBondContact OD1-N 3.25Å; D248-R252 WeakPolarHBondContact O-CG 3.33Å; D248-R252 PolarHBondContact O-N 3.01Å
249E93Very high90.6Very high139 Ų13944.6 Ų44.665%0.6522%0.215SC*.Hα-helixtrans-61.3-37.4179.8-79.3176.2-162.100112.9M247 F251 R252 M253M247-E249 PolarHBondContact O-N 2.91Å; E249-F251 VanDerWaalsContact C-N 3.32Å; E249-R252 VanDerWaalsContact CG-NH2 3.3Å; E249-R252 PolarHBondContact O-N 3.41Å; E249-M253 PolarHBondContact O-N 3.37Å
250D92.3Very high90.2Very high36 Ų3645.8 Ų45.819%0.19322%0.222CC..Hα-helixtrans-69.7-37179.1-64.4-35000111D248 M253 E254 S500 Q503D248-D250 VanDerWaalsContact C-N 3.31Å; D248-D250 PolarHBondContact O-N 2.83Å; D248-D250 WeakPolarHBondContact OD1-CB 3.21Å; D248-D250 PolarHBondContact OD1-N 3.01Å; D250-M253 PolarHBondContact O-N 2.92Å; D250-E254 PolarHBondContact O-N 3.48Å; D250-S500 WeakPolarHBondContact CA-OG 3.32Å; D250-S500 WeakPolarHBondContact CB-O 3.45Å; D250-S500 WeakPolarHBondContact OD1-CA 3.33Å; D250-S500 VanDerWaalsContact OD1-CB 3.31Å; D250-S500 WeakPolarHBondContact OD1-CB 3.37Å; D250-S500 PolarHBondContact OD1-OG 3.35Å; D250-Q503 WeakPolarHBondContact OD2-CB 3.48Å
251F89.6Confident89.8Confident8 Ų845 Ų454%0.03523%0.228CC..Hα-helixtrans-64.3-47.5171.8-179.9-106.5000112.3V128 I245 D248 E249 M253 E254 F255 N511 L515V128-F251 HydrophobicContact CB-CD1 4.23Å; V128-F251 HydrophobicContact CB-CE1 3.74Å; V128-F251 HydrophobicContact CG1-CD1 3.85Å; V128-F251 HydrophobicContact CG1-CE1 3.42Å; V128-F251 VanDerWaalsContact CG1-CE1 3.42Å; V128-F251 HydrophobicContact CG1-CZ 4.39Å; I245-F251 HydrophobicContact CB-CD1 4.47Å; I245-F251 HydrophobicContact CG2-CD1 3.26Å; I245-F251 HydrophobicContact CG2-CE1 3.2Å; I245-F251 HydrophobicContact CG2-CG 3.96Å; I245-F251 HydrophobicContact CG2-CZ 3.92Å; I245-F251 WeakPolarHBondContact O-CD1 3.03Å; D248-F251 HydrophobicContact CB-CB 3.77Å; D248-F251 WeakPolarHBondContact O-CB 3.44Å; D248-F251 PolarHBondContact O-N 3.32Å; D248-F251 PolarHBondContact OD1-N 3.25Å; E249-F251 VanDerWaalsContact C-N 3.32Å; F251-M253 VanDerWaalsContact C-N 3.26Å; F251-M253 PolarHBondContact O-N 2.91Å; F251-E254 PolarHBondContact O-N 2.96Å; F251-F255 HydrophobicContact CE1-CB 4.46Å; F251-F255 HydrophobicContact CE1-CD2 4.28Å; F251-F255 HydrophobicContact CZ-CB 4.4Å; F251-F255 AromaticContact CZ-CD2 3.84Å; F251-F255 HydrophobicContact CZ-CD2 3.84Å; F251-F255 HydrophobicContact CZ-CG 4.48Å; F251-F255 WeakPolarHBondContact O-CB 3.36Å; F251-F255 PolarHBondContact O-N 3.41Å; F251-N511 HydrophobicContact CD2-CB 3.97Å; F251-N511 VanDerWaalsContact CD2-CG 3.47Å; F251-N511 WeakPolarHBondContact CD2-ND2 3.48Å; F251-N511 HydrophobicContact CE2-CB 3.08Å; F251-N511 WeakPolarHBondContact CE2-ND2 3.32Å; F251-N511 HydrophobicContact CZ-CB 3.53Å; F251-L515 HydrophobicContact CE1-CD1 4.45Å; F251-L515 HydrophobicContact CZ-CD1 4.3Å
252R92.4Very high89.8Confident12 Ų1242.2 Ų42.25%0.04521%0.214CC..Hα-helixtrans-59.4-39.7178.1-72.3-174.3-62.3138.1-23.9111.4D121 E124 V128 R246 D248 E249 F255 L256D121-R252 IonicContact OD1-CZ 2.75Å; D121-R252 IonicContact OD1-NH1 2.62Å; D121-R252 PolarHBondContact OD1-NH1 3.23Å; D121-R252 IonicContact OD1-NH2 2.8Å; D121-R252 PolarHBondContact OD1-NH2 2.93Å; E124-R252 IonicContact OE2-CZ 3.33Å; E124-R252 IonicContact OE2-NH1 4Å; E124-R252 PolarHBondContact OE2-NH1 3.46Å; V128-R252 HydrophobicContact CG1-CG 4.09Å; V128-R252 HydrophobicContact CG2-CG 3.96Å; R246-R252 WeakPolarHBondContact O-CD 3.45Å; D248-R252 WeakPolarHBondContact O-CG 3.33Å; D248-R252 PolarHBondContact O-N 3.01Å; E249-R252 VanDerWaalsContact CG-NH2 3.3Å; E249-R252 PolarHBondContact O-N 3.41Å; R252-F255 PolarHBondContact O-N 3.46Å; R252-L256 VanDerWaalsContact O-CG 3.32Å; R252-L256 WeakPolarHBondContact O-CG 3.27Å; R252-L256 PolarHBondContact O-N 2.91Å
253M93.9Very high89.6Confident20 Ų2044.8 Ų44.810%0.09924%0.236CC..Hα-helixtrans-61.5-48.5174.7-169.96870.300112.1L166 K169 E249 D250 F251 F255 L256 F257 I497 S500 L501L166-M253 HydrophobicContact CD2-SD 4.41Å; K169-M253 HydrophobicContact CD-CE 3.87Å; K169-M253 HydrophobicContact CD-SD 4.35Å; K169-M253 HydrophobicContact CG-CE 4.22Å; K169-M253 HydrophobicContact CG-SD 4.21Å; E249-M253 PolarHBondContact O-N 3.37Å; D250-M253 PolarHBondContact O-N 2.92Å; F251-M253 VanDerWaalsContact C-N 3.26Å; F251-M253 PolarHBondContact O-N 2.91Å; M253-F255 VanDerWaalsContact C-N 3.26Å; M253-F255 PolarHBondContact O-N 2.9Å; M253-L256 WeakPolarHBondContact O-CB 3.28Å; M253-L256 PolarHBondContact O-N 3.22Å; M253-L256 HydrophobicContact SD-CD1 4.13Å; M253-F257 WeakPolarHBondContact O-CD2 3.32Å; M253-I497 HydrophobicContact CE-CG1 4.31Å; M253-I497 HydrophobicContact CG-CG2 4.31Å; M253-I497 HydrophobicContact SD-CB 4.46Å; M253-I497 HydrophobicContact SD-CG1 4.12Å; M253-I497 HydrophobicContact SD-CG2 4.07Å; M253-S500 WeakPolarHBondContact CB-OG 3.06Å; M253-L501 HydrophobicContact CG-CD2 4Å; M253-L501 HydrophobicContact CG-CG 4.28Å
254E90.5Very high89.5Confident21 Ų2143.9 Ų43.910%0.09824%0.24CC..Hα-helixtrans-59.9-37.8175.5178.367.1-166.800111.3D250 F251 L256 F257 S262 L501D250-E254 PolarHBondContact O-N 3.48Å; F251-E254 PolarHBondContact O-N 2.96Å; E254-L256 VanDerWaalsContact C-N 3.27Å; E254-L256 PolarHBondContact O-N 3.3Å; E254-F257 WeakPolarHBondContact O-CB 3.49Å; E254-F257 PolarHBondContact O-N 3.48Å; E254-F257 VanDerWaalsContact O-N 3.14Å; E254-S262 VanDerWaalsContact CD-OG 3.28Å; E254-S262 PolarHBondContact OE1-OG 3.19Å; E254-S262 VanDerWaalsContact OE1-OG 3.05Å; E254-S262 VanDerWaalsContact OE2-CB 3.24Å; E254-S262 WeakPolarHBondContact OE2-CB 3.46Å; E254-S262 PolarHBondContact OE2-OG 3.43Å; E254-L501 HydrophobicContact CB-CD2 4.16Å; E254-L501 VanDerWaalsContact OE2-CD2 3.25Å; E254-L501 WeakPolarHBondContact OE2-CD2 3.4Å
255F89.8Confident89.6Confident31 Ų3137.2 Ų37.214%0.13621%0.211CC..Hα-helixtrans-65.9-26178.9-162.9-99000113.4A127 V128 Q159 F251 R252 M253 F257 Q258 L515A127-F255 HydrophobicContact CB-CD1 4.1Å; A127-F255 HydrophobicContact CB-CE1 3.84Å; A127-F255 WeakPolarHBondContact O-CE1 3.45Å; A127-F255 WeakPolarHBondContact O-CZ 3.23Å; V128-F255 HydrophobicContact CG1-CB 3.78Å; V128-F255 HydrophobicContact CG1-CD1 3.67Å; V128-F255 HydrophobicContact CG1-CD2 4.11Å; V128-F255 HydrophobicContact CG1-CE1 4.24Å; V128-F255 HydrophobicContact CG1-CG 3.58Å; Q159-F255 HydrophobicContact CG-CE1 4.07Å; Q159-F255 HydrophobicContact CG-CZ 4.1Å; F251-F255 HydrophobicContact CE1-CB 4.46Å; F251-F255 HydrophobicContact CE1-CD2 4.28Å; F251-F255 HydrophobicContact CZ-CB 4.4Å; F251-F255 AromaticContact CZ-CD2 3.84Å; F251-F255 HydrophobicContact CZ-CD2 3.84Å; F251-F255 HydrophobicContact CZ-CG 4.48Å; F251-F255 WeakPolarHBondContact O-CB 3.36Å; F251-F255 PolarHBondContact O-N 3.41Å; R252-F255 PolarHBondContact O-N 3.46Å; M253-F255 VanDerWaalsContact C-N 3.26Å; M253-F255 PolarHBondContact O-N 2.9Å; F255-F257 PolarHBondContact O-N 3.25Å; F255-Q258 PolarHBondContact O-N 3.44Å; F255-Q258 VanDerWaalsContact O-N 3.1Å; F255-Q258 PolarHBondContact O-NE2 3.49Å; F255-L515 HydrophobicContact CE2-CD1 3.87Å; F255-L515 HydrophobicContact CZ-CD1 4.43Å
256L91.8Very high89.8Confident2 Ų238.3 Ų38.31%0.0122%0.217CC..THydrogen-bonded Turntrans-63.2-24.1175-51.4-172.1000112.5E124 C162 P163 I165 L166 K169 R252 M253 E254 Q258 V386E124-L256 HydrophobicContact CG-CD2 4.19Å; C162-L256 HydrophobicContact CB-CD2 3.88Å; C162-L256 WeakPolarHBondContact O-CD2 3.18Å; P163-L256 WeakPolarHBondContact CA-O 3.4Å; I165-L256 HydrophobicContact CB-CD1 4.34Å; I165-L256 HydrophobicContact CB-CD2 4.44Å; I165-L256 HydrophobicContact CG2-CD1 4.43Å; L166-L256 HydrophobicContact CD1-CB 4.46Å; L166-L256 HydrophobicContact CD2-CB 4.17Å; L166-L256 HydrophobicContact CD2-CD1 3.88Å; L166-L256 HydrophobicContact CG-CB 4.08Å; L166-L256 HydrophobicContact CG-CD1 4.15Å; K169-L256 VanDerWaalsContact CE-CD1 3.45Å; K169-L256 HydrophobicContact CG-CD1 4.38Å; R252-L256 VanDerWaalsContact O-CG 3.32Å; R252-L256 WeakPolarHBondContact O-CG 3.27Å; R252-L256 PolarHBondContact O-N 2.91Å; M253-L256 WeakPolarHBondContact O-CB 3.28Å; M253-L256 PolarHBondContact O-N 3.22Å; M253-L256 HydrophobicContact SD-CD1 4.13Å; E254-L256 VanDerWaalsContact C-N 3.27Å; E254-L256 PolarHBondContact O-N 3.3Å; L256-Q258 PolarHBondContact O-N 2.98Å; L256-V386 WeakPolarHBondContact O-CG1 3.43Å
257F89.6Confident89.9Confident1 Ų142 Ų420%0.00424%0.242CC..THydrogen-bonded Turntrans-75-11.4178.6-75.3-105.4000113.3L166 M253 E254 F255 D259 V260 F265 L383 V386 I497 L501L166-F257 HydrophobicContact CD1-CE2 4.43Å; L166-F257 HydrophobicContact CD2-CE2 4.09Å; M253-F257 WeakPolarHBondContact O-CD2 3.32Å; E254-F257 WeakPolarHBondContact O-CB 3.49Å; E254-F257 PolarHBondContact O-N 3.48Å; E254-F257 VanDerWaalsContact O-N 3.14Å; F255-F257 PolarHBondContact O-N 3.25Å; F257-D259 PolarHBondContact O-N 3.49Å; F257-V260 WeakPolarHBondContact O-CA 3.29Å; F257-V260 PolarHBondContact O-N 3.01Å; F257-F265 HydrophobicContact CE1-CB 3.86Å; F257-F265 HydrophobicContact CE1-CD1 4.49Å; F257-F265 HydrophobicContact CE1-CG 4.26Å; F257-F265 HydrophobicContact CZ-CB 4.35Å; F257-F265 HydrophobicContact CZ-CD1 4.15Å; F257-F265 HydrophobicContact CZ-CG 4.26Å; F257-L383 HydrophobicContact CE1-CD2 4.15Å; F257-L383 HydrophobicContact CZ-CD2 3.75Å; F257-V386 HydrophobicContact CD1-CG1 4.41Å; F257-V386 HydrophobicContact CD1-CG2 3.52Å; F257-V386 HydrophobicContact CE1-CG2 3.74Å; F257-V386 HydrophobicContact CG-CG1 4.46Å; F257-V386 HydrophobicContact CG-CG2 4.33Å; F257-I497 HydrophobicContact CE2-CG2 4.23Å; F257-I497 HydrophobicContact CZ-CG2 4.24Å; F257-L501 HydrophobicContact CD2-CD1 4.47Å; F257-L501 HydrophobicContact CD2-CD2 3.8Å; F257-L501 HydrophobicContact CE1-CD1 4.41Å; F257-L501 HydrophobicContact CE2-CD1 3.68Å; F257-L501 HydrophobicContact CE2-CD2 3.67Å; F257-L501 HydrophobicContact CE2-CG 4.22Å; F257-L501 HydrophobicContact CZ-CD1 3.64Å; F257-L501 HydrophobicContact CZ-CD2 4.45Å
258Q85.3Confident89.9Confident46 Ų4640.6 Ų40.622%0.21524%0.236CC..THydrogen-bonded Turntrans41.2-113.7177.2-73.9-60.7-3900111.5C162 P163 F255 L256 K508C162-Q258 PolarHBondContact SG-NE2 3.31Å; P163-Q258 HydrophobicContact CG-CB 4.18Å; P163-Q258 HydrophobicContact CG-CG 3.6Å; F255-Q258 PolarHBondContact O-N 3.44Å; F255-Q258 VanDerWaalsContact O-N 3.1Å; F255-Q258 PolarHBondContact O-NE2 3.49Å; L256-Q258 PolarHBondContact O-N 2.98Å; Q258-K508 WeakPolarHBondContact O-CE 3.37Å; Q258-K508 PolarHBondContact O-NZ 2.99Å
259D79.6Confident90Very high112 Ų11238.2 Ų38.260%0.59922%0.223SC*.THydrogen-bonded Turntrans-85.9-16.6-177.2-71.7-36.9000113.8F257 K508 K512F257-D259 PolarHBondContact O-N 3.49Å; D259-K508 VanDerWaalsContact C-NZ 3.27Å; D259-K508 PolarHBondContact O-NZ 3.11Å; D259-K508 VanDerWaalsContact O-NZ 3.13Å; D259-K512 IonicContact OD1-NZ 3.93Å
260V83.1Confident90.2Very high25 Ų2536.2 Ų36.215%0.15221%0.213CC..SBendtrans-72.8143173.2170.30000109.2F257 E385 V386 Q389 K508F257-V260 WeakPolarHBondContact O-CA 3.29Å; F257-V260 PolarHBondContact O-N 3.01Å; V260-E385 HydrophobicContact CG2-CG 4.39Å; V260-V386 HydrophobicContact CB-CG2 3.95Å; V260-V386 HydrophobicContact CG1-CG2 3.73Å; V260-V386 HydrophobicContact CG2-CG2 4.31Å; V260-Q389 HydrophobicContact CG2-CG 4.2Å; V260-K508 PolarHBondContact O-NZ 3.31Å
261C83.4Confident90.3Very high82 Ų8239.7 Ų39.755%0.55423%0.228SC*.  trans-80.7118.5175.7-172.40000110.4A263 G264C261-A263 PolarHBondContact O-N 2.9Å; C261-A263 VanDerWaalsContact SG-CB 3.56Å; C261-G264 PolarHBondContact O-N 3.35Å; C261-G264 VanDerWaalsContact O-N 3.15Å
262S88.6Confident90.4Very high10 Ų1039.5 Ų39.57%0.0723%0.228CC..Hα-helixtrans-60.7-26.5176.9600000113E254 G264 F265 I266E254-S262 VanDerWaalsContact CD-OG 3.28Å; E254-S262 PolarHBondContact OE1-OG 3.19Å; E254-S262 VanDerWaalsContact OE1-OG 3.05Å; E254-S262 VanDerWaalsContact OE2-CB 3.24Å; E254-S262 WeakPolarHBondContact OE2-CB 3.46Å; E254-S262 PolarHBondContact OE2-OG 3.43Å; S262-G264 PolarHBondContact O-N 3.46Å; S262-G264 VanDerWaalsContact O-N 3.16Å; S262-F265 PolarHBondContact O-N 3.07Å; S262-F265 VanDerWaalsContact O-N 3.11Å; S262-I266 WeakPolarHBondContact O-CG1 3.3Å; S262-I266 PolarHBondContact O-N 3.47Å
263A88.6Confident90.4Very high55 Ų5540.3 Ų40.346%0.45523%0.232SC..Hα-helixtrans-58.4-29.1176.100000113.4C261 S267C261-A263 PolarHBondContact O-N 2.9Å; C261-A263 VanDerWaalsContact SG-CB 3.56Å; A263-S267 VanDerWaalsContact O-CB 3.27Å; A263-S267 WeakPolarHBondContact O-CB 3.49Å; A263-S267 PolarHBondContact O-N 3.33Å
264G89.7Confident90.3Very high37 Ų3743 Ų4338%0.38125%0.251SS..Hα-helixtrans-62.8-50.8174.500000111.6C261 S262 S267 I268C261-G264 PolarHBondContact O-N 3.35Å; C261-G264 VanDerWaalsContact O-N 3.15Å; S262-G264 PolarHBondContact O-N 3.46Å; S262-G264 VanDerWaalsContact O-N 3.16Å; G264-S267 PolarHBondContact O-N 3.34Å; G264-I268 VanDerWaalsContact O-CG1 3.29Å; G264-I268 WeakPolarHBondContact O-CG1 3.19Å; G264-I268 PolarHBondContact O-N 3.05Å
265F92.6Very high90.1Very high4 Ų445.7 Ų45.72%0.01826%0.262CS..Hα-helixtrans-60-48.8174.8167.7-100000111.6F257 S262 S267 I268 F269 V379 S382 L383 W494 I497 C498 L501F257-F265 HydrophobicContact CE1-CB 3.86Å; F257-F265 HydrophobicContact CE1-CD1 4.49Å; F257-F265 HydrophobicContact CE1-CG 4.26Å; F257-F265 HydrophobicContact CZ-CB 4.35Å; F257-F265 HydrophobicContact CZ-CD1 4.15Å; F257-F265 HydrophobicContact CZ-CG 4.26Å; S262-F265 PolarHBondContact O-N 3.07Å; S262-F265 VanDerWaalsContact O-N 3.11Å; F265-S267 VanDerWaalsContact C-N 3.33Å; F265-S267 PolarHBondContact O-N 3.12Å; F265-I268 PolarHBondContact O-N 3.21Å; F265-F269 HydrophobicContact CE2-CB 4.45Å; F265-F269 HydrophobicContact CZ-CB 4.35Å; F265-F269 HydrophobicContact CZ-CG 4.45Å; F265-F269 VanDerWaalsContact O-CB 3.26Å; F265-F269 WeakPolarHBondContact O-CB 3.22Å; F265-F269 PolarHBondContact O-N 3.29Å; F265-V379 HydrophobicContact CE2-CG1 3.89Å; F265-S382 WeakPolarHBondContact CD2-OG 3.49Å; F265-L383 HydrophobicContact CD2-CD1 4.34Å; F265-L383 HydrophobicContact CD2-CD2 3.52Å; F265-L383 HydrophobicContact CD2-CG 3.68Å; F265-L383 HydrophobicContact CE2-CD1 3.76Å; F265-L383 HydrophobicContact CE2-CD2 3.65Å; F265-L383 HydrophobicContact CE2-CG 3.63Å; F265-L383 HydrophobicContact CG-CD2 4.02Å; F265-L383 HydrophobicContact CZ-CD1 4.41Å; F265-L383 HydrophobicContact CZ-CD2 4.22Å; F265-W494 HydrophobicContact CZ-CB 4.17Å; F265-I497 HydrophobicContact CD1-CG2 4.39Å; F265-I497 HydrophobicContact CE1-CB 4.18Å; F265-I497 HydrophobicContact CE1-CG2 3.69Å; F265-I497 HydrophobicContact CZ-CB 4.31Å; F265-I497 HydrophobicContact CZ-CG2 4.12Å; F265-C498 HydrophobicContact CE1-CB 3.93Å; F265-L501 HydrophobicContact CD1-CD1 3.62Å; F265-L501 HydrophobicContact CE1-CD1 3.98Å
266I94.5Very high89.9Confident29 Ų2944.2 Ų44.215%0.14926%0.256CS..Hα-helixtrans-56.6-47.6-179.7-65.1168.3000111S262 F269 H270 L501S262-I266 WeakPolarHBondContact O-CG1 3.3Å; S262-I266 PolarHBondContact O-N 3.47Å; I266-F269 PolarHBondContact O-N 3.27Å; I266-H270 WeakPolarHBondContact O-CB 3.4Å; I266-H270 PolarHBondContact O-N 3.48Å; I266-L501 HydrophobicContact CD1-CB 3.82Å; I266-L501 HydrophobicContact CG1-CB 4.21Å; I266-L501 HydrophobicContact CG1-CD1 4.2Å
267S94.4Very high89.6Confident77 Ų7746.7 Ų46.754%0.53827%0.269SS..Hα-helixtrans-62.5-49.1-179.7-1770000111.8A263 G264 F265 F269 E271A263-S267 VanDerWaalsContact O-CB 3.27Å; A263-S267 WeakPolarHBondContact O-CB 3.49Å; A263-S267 PolarHBondContact O-N 3.33Å; G264-S267 PolarHBondContact O-N 3.34Å; F265-S267 VanDerWaalsContact C-N 3.33Å; F265-S267 PolarHBondContact O-N 3.12Å; S267-F269 PolarHBondContact O-N 3.1Å; S267-E271 WeakPolarHBondContact O-CB 3.46Å; S267-E271 PolarHBondContact O-N 3.11Å; S267-E271 VanDerWaalsContact O-N 3.1Å
268I93.9Very high89.2Confident54 Ų5452.7 Ų52.728%0.27730%0.295SS..Hα-helixtrans-61.4-46.3178.3-68.2167.7000110G264 F265 E271 Q272 K378 V379G264-I268 VanDerWaalsContact O-CG1 3.29Å; G264-I268 WeakPolarHBondContact O-CG1 3.19Å; G264-I268 PolarHBondContact O-N 3.05Å; F265-I268 PolarHBondContact O-N 3.21Å; I268-E271 PolarHBondContact O-N 3.38Å; I268-Q272 HydrophobicContact CG2-CG 4.26Å; I268-Q272 WeakPolarHBondContact O-CG 3.47Å; I268-Q272 PolarHBondContact O-N 3.48Å; I268-K378 HydrophobicContact CG2-CB 4.08Å; I268-V379 HydrophobicContact CG2-CG2 4.12Å
269F94.6Very high88.9Confident2 Ų251.8 Ų51.81%0.00929%0.29CS..Hα-helixtrans-62.1-51.2-179.1-178.1-106.6000111.8F265 I266 S267 E271 Q272 Q273 V379 I491 W494 E495 C498F265-F269 HydrophobicContact CE2-CB 4.45Å; F265-F269 HydrophobicContact CZ-CB 4.35Å; F265-F269 HydrophobicContact CZ-CG 4.45Å; F265-F269 VanDerWaalsContact O-CB 3.26Å; F265-F269 WeakPolarHBondContact O-CB 3.22Å; F265-F269 PolarHBondContact O-N 3.29Å; I266-F269 PolarHBondContact O-N 3.27Å; S267-F269 PolarHBondContact O-N 3.1Å; F269-E271 PolarHBondContact O-N 3.26Å; F269-Q272 PolarHBondContact O-N 3.29Å; F269-Q272 VanDerWaalsContact O-N 3.16Å; F269-Q273 HydrophobicContact CD2-CB 4.46Å; F269-Q273 HydrophobicContact CE1-CB 4.16Å; F269-Q273 HydrophobicContact CE1-CG 4.05Å; F269-Q273 HydrophobicContact CE2-CB 4.1Å; F269-Q273 HydrophobicContact CE2-CG 4.14Å; F269-Q273 HydrophobicContact CZ-CB 3.94Å; F269-Q273 HydrophobicContact CZ-CG 3.64Å; F269-Q273 WeakPolarHBondContact O-CB 3.48Å; F269-Q273 PolarHBondContact O-N 2.87Å; F269-V379 HydrophobicContact CD2-CG1 3.9Å; F269-V379 HydrophobicContact CD2-CG2 4.43Å; F269-I491 HydrophobicContact CE2-CG2 4.23Å; F269-I491 HydrophobicContact CZ-CG2 4.29Å; F269-W494 HydrophobicContact CD2-CB 3.81Å; F269-W494 HydrophobicContact CD2-CE3 4.43Å; F269-W494 HydrophobicContact CE2-CB 3.41Å; F269-W494 VanDerWaalsContact CE2-CB 3.41Å; F269-W494 HydrophobicContact CE2-CE3 4.14Å; F269-W494 HydrophobicContact CE2-CG 4.39Å; F269-W494 HydrophobicContact CZ-CB 4.03Å; F269-E495 HydrophobicContact CE1-CB 4Å; F269-E495 HydrophobicContact CE1-CG 4.45Å; F269-E495 HydrophobicContact CZ-CB 3.77Å; F269-C498 HydrophobicContact CD1-CB 3.61Å; F269-C498 HydrophobicContact CE1-CB 3.98Å; F269-C498 HydrophobicContact CG-CB 4.41Å
270H95.9Very high88.9Confident96 Ų9646.5 Ų46.544%0.44426%0.262SS..Hα-helixtrans-58-34.8177.3-74.9171.9000112.8I266 P274 C498I266-H270 WeakPolarHBondContact O-CB 3.4Å; I266-H270 PolarHBondContact O-N 3.48Å; H270-P274 VanDerWaalsContact O-CD 3.31Å; H270-P274 WeakPolarHBondContact O-CD 3.36Å; H270-C498 PolarHBondContact NE2-SG 2.98Å; H270-C498 VanDerWaalsContact NE2-SG 3.39Å
271E94.8Very high88.6Confident109 Ų10949 Ų4951%0.50928%0.275SS..Hα-helixtrans-72.7-40.3177.5-159.5-150129.700112.7S267 I268 F269 K275S267-E271 WeakPolarHBondContact O-CB 3.46Å; S267-E271 PolarHBondContact O-N 3.11Å; S267-E271 VanDerWaalsContact O-N 3.1Å; I268-E271 PolarHBondContact O-N 3.38Å; F269-E271 PolarHBondContact O-N 3.26Å; E271-K275 VanDerWaalsContact O-CE 3.27Å; E271-K275 WeakPolarHBondContact O-CE 3.18Å; E271-K275 IonicContact OE1-NZ 4Å; E271-K275 PolarHBondContact OE1-NZ 3.29Å
272Q90.8Very high88Confident4 Ų446.6 Ų46.62%0.01926%0.256CS..Hα-helixtrans-89.3-33.1-174.6-55-37-38.900113.8I268 F269 K275 L276 D375 V379I268-Q272 HydrophobicContact CG2-CG 4.26Å; I268-Q272 WeakPolarHBondContact O-CG 3.47Å; I268-Q272 PolarHBondContact O-N 3.48Å; F269-Q272 PolarHBondContact O-N 3.29Å; F269-Q272 VanDerWaalsContact O-N 3.16Å; Q272-K275 WeakPolarHBondContact O-CA 3.48Å; Q272-K275 WeakPolarHBondContact O-CB 3.28Å; Q272-K275 PolarHBondContact O-N 3.2Å; Q272-L276 HydrophobicContact CB-CD1 4.2Å; Q272-L276 HydrophobicContact CB-CG 4.48Å; Q272-L276 WeakPolarHBondContact O-CG 3.42Å; Q272-L276 PolarHBondContact O-N 2.74Å; Q272-D375 HydrophobicContact CB-CB 4.43Å; Q272-D375 HydrophobicContact CG-CB 4.39Å; Q272-D375 VanDerWaalsContact OE1-CG 3.31Å; Q272-D375 PolarHBondContact OE1-OD1 2.85Å; Q272-V379 HydrophobicContact CB-CG2 3.86Å; Q272-V379 HydrophobicContact CG-CG2 4.11Å
273Q93.7Very high87.2Confident30 Ų3047 Ų4714%0.1426%0.258CS..Hα-helixtrans-48-52.2-176.4-173.5-165.927.500113.7F269 K275 L276 L277 I491 E495F269-Q273 HydrophobicContact CD2-CB 4.46Å; F269-Q273 HydrophobicContact CE1-CB 4.16Å; F269-Q273 HydrophobicContact CE1-CG 4.05Å; F269-Q273 HydrophobicContact CE2-CB 4.1Å; F269-Q273 HydrophobicContact CE2-CG 4.14Å; F269-Q273 HydrophobicContact CZ-CB 3.94Å; F269-Q273 HydrophobicContact CZ-CG 3.64Å; F269-Q273 WeakPolarHBondContact O-CB 3.48Å; F269-Q273 PolarHBondContact O-N 2.87Å; Q273-K275 VanDerWaalsContact C-N 3.27Å; Q273-K275 PolarHBondContact O-N 3.31Å; Q273-L276 PolarHBondContact O-N 2.9Å; Q273-L277 HydrophobicContact CG-CD1 3.92Å; Q273-L277 HydrophobicContact CG-CG 4.31Å; Q273-L277 WeakPolarHBondContact O-CG 3.36Å; Q273-L277 PolarHBondContact O-N 3.34Å; Q273-I491 HydrophobicContact CG-CG2 4.08Å; Q273-E495 PolarHBondContact NE2-OE1 3.01Å; Q273-E495 VanDerWaalsContact NE2-OE1 3.14Å; Q273-E495 PolarHBondContact NE2-OE2 2.75Å
274P90.7Very high86.4Confident77 Ų7747 Ų4750%0.525%0.249SC..Hα-helixtrans-65.1-30.1-179.425-34.8000113H270 K278H270-P274 VanDerWaalsContact O-CD 3.31Å; H270-P274 WeakPolarHBondContact O-CD 3.36Å; P274-K278 WeakPolarHBondContact O-CB 3.41Å; P274-K278 PolarHBondContact O-N 3.18Å; P274-K278 VanDerWaalsContact O-N 3.12Å
275K86.6Confident85.4Confident76 Ų7650.6 Ų50.633%0.3326%0.256SS..Hα-helixtrans-71.2-43.7176.8-54.6174.8-163159.10110.4E271 Q272 Q273 F279E271-K275 VanDerWaalsContact O-CE 3.27Å; E271-K275 WeakPolarHBondContact O-CE 3.18Å; E271-K275 IonicContact OE1-NZ 4Å; E271-K275 PolarHBondContact OE1-NZ 3.29Å; Q272-K275 WeakPolarHBondContact O-CA 3.48Å; Q272-K275 WeakPolarHBondContact O-CB 3.28Å; Q272-K275 PolarHBondContact O-N 3.2Å; Q273-K275 VanDerWaalsContact C-N 3.27Å; Q273-K275 PolarHBondContact O-N 3.31Å; K275-F279 PolarHBondContact O-N 3.22Å; K275-F279 VanDerWaalsContact O-N 3.1Å
276L84.9Confident84.1Confident0 Ų051.3 Ų51.30%026%0.261CS..Hα-helixtrans-64.5-50.8177.9-64.8173.3000111.3Q272 Q273 K278 F279 L280 F372 D375 F376 V379 I491 W494Q272-L276 HydrophobicContact CB-CD1 4.2Å; Q272-L276 HydrophobicContact CB-CG 4.48Å; Q272-L276 WeakPolarHBondContact O-CG 3.42Å; Q272-L276 PolarHBondContact O-N 2.74Å; Q273-L276 PolarHBondContact O-N 2.9Å; L276-K278 PolarHBondContact O-N 3.17Å; L276-F279 WeakPolarHBondContact O-CB 3.45Å; L276-F279 PolarHBondContact O-N 2.92Å; L276-L280 WeakPolarHBondContact O-CG 3.36Å; L276-L280 PolarHBondContact O-N 2.91Å; L276-F372 HydrophobicContact CB-CE2 4.41Å; L276-F372 HydrophobicContact CD2-CD2 3.55Å; L276-F372 HydrophobicContact CD2-CE2 3.57Å; L276-F372 HydrophobicContact CD2-CG 4.47Å; L276-F372 HydrophobicContact CD2-CZ 4.48Å; L276-D375 HydrophobicContact CD2-CB 4.01Å; L276-F376 HydrophobicContact CD1-CD2 4.23Å; L276-F376 HydrophobicContact CD2-CB 3.94Å; L276-F376 HydrophobicContact CD2-CD2 4.21Å; L276-V379 HydrophobicContact CD1-CG2 4.4Å; L276-I491 HydrophobicContact CB-CD1 3.67Å; L276-I491 HydrophobicContact CD1-CD1 4.32Å; L276-I491 HydrophobicContact CD1-CG1 4.41Å; L276-W494 HydrophobicContact CD1-CZ3 4.28Å
277L86.5Confident82.7Confident54 Ų5449.9 Ų49.928%0.28325%0.254SS..Hα-helixtrans-61.3-43.4179.3-70.9178.7000111.9Q273 F279 L280 D281 I491Q273-L277 HydrophobicContact CG-CD1 3.92Å; Q273-L277 HydrophobicContact CG-CG 4.31Å; Q273-L277 WeakPolarHBondContact O-CG 3.36Å; Q273-L277 PolarHBondContact O-N 3.34Å; L277-F279 VanDerWaalsContact C-N 3.31Å; L277-F279 PolarHBondContact O-N 3.43Å; L277-L280 PolarHBondContact O-N 2.98Å; L277-L280 VanDerWaalsContact O-N 3.11Å; L277-D281 PolarHBondContact O-N 3.45Å; L277-I491 HydrophobicContact CD2-CD1 4.28Å; L277-I491 HydrophobicContact CD2-CG2 3.94Å; L277-I491 HydrophobicContact CG-CG2 4.26Å
278K81.1Confident81.4Confident127 Ų12747.7 Ų47.755%0.55224%0.24SC*.Hα-helixtrans-58.6-43.1175.5-179.7170.4-178.6169.30112.2P274 L276 L280 D281 D282P274-K278 WeakPolarHBondContact O-CB 3.41Å; P274-K278 PolarHBondContact O-N 3.18Å; P274-K278 VanDerWaalsContact O-N 3.12Å; L276-K278 PolarHBondContact O-N 3.17Å; K278-L280 VanDerWaalsContact C-N 3.32Å; K278-L280 PolarHBondContact O-N 3.47Å; K278-D281 PolarHBondContact O-N 3.08Å; K278-D282 PolarHBondContact O-N 2.93Å
279F79.3Confident79.9Confident27 Ų2749.8 Ų49.812%0.11825%0.249CC..Hα-helixtrans-60.6-42.1175.7176.2-94.6000111.8K275 L276 L277 D282 V283 V368 F369 F372K275-F279 PolarHBondContact O-N 3.22Å; K275-F279 VanDerWaalsContact O-N 3.1Å; L276-F279 WeakPolarHBondContact O-CB 3.45Å; L276-F279 PolarHBondContact O-N 2.92Å; L277-F279 VanDerWaalsContact C-N 3.31Å; L277-F279 PolarHBondContact O-N 3.43Å; F279-D282 PolarHBondContact O-N 3.38Å; F279-V283 HydrophobicContact CD1-CG2 4.21Å; F279-V283 HydrophobicContact CE1-CG2 3.76Å; F279-V283 HydrophobicContact CE2-CG2 4.46Å; F279-V283 HydrophobicContact CZ-CG2 3.89Å; F279-V283 WeakPolarHBondContact O-CG2 3.32Å; F279-V283 PolarHBondContact O-N 3.3Å; F279-V368 HydrophobicContact CD2-CG1 3.92Å; F279-V368 HydrophobicContact CE2-CG1 3.78Å; F279-F369 HydrophobicContact CE1-CD1 4.4Å; F279-F369 HydrophobicContact CE1-CE1 4.14Å; F279-F369 AromaticContact CZ-CD1 3.68Å; F279-F369 HydrophobicContact CZ-CD1 3.68Å; F279-F369 HydrophobicContact CZ-CD2 4.49Å; F279-F369 AromaticContact CZ-CE1 3.5Å; F279-F369 HydrophobicContact CZ-CE1 3.5Å; F279-F369 HydrophobicContact CZ-CE2 4.32Å; F279-F369 HydrophobicContact CZ-CG 4.19Å; F279-F369 AromaticContact CZ-CZ 3.83Å; F279-F369 HydrophobicContact CZ-CZ 3.83Å; F279-F372 HydrophobicContact CB-CD2 3.96Å; F279-F372 HydrophobicContact CD1-CB 3.99Å; F279-F372 HydrophobicContact CD1-CD1 4.16Å; F279-F372 AromaticContact CD1-CD2 3.13Å; F279-F372 HydrophobicContact CD1-CD2 3.13Å; F279-F372 HydrophobicContact CD1-CE1 4.49Å; F279-F372 AromaticContact CD1-CE2 3.54Å; F279-F372 HydrophobicContact CD1-CE2 3.54Å; F279-F372 AromaticContact CD1-CG 3.48Å; F279-F372 HydrophobicContact CD1-CG 3.48Å; F279-F372 VanDerWaalsContact CD1-CG 3.48Å; F279-F372 HydrophobicContact CD1-CZ 4.21Å; F279-F372 HydrophobicContact CD2-CB 4.22Å; F279-F372 HydrophobicContact CE1-CB 4.01Å; F279-F372 AromaticContact CE1-CD1 3.85Å; F279-F372 HydrophobicContact CE1-CD1 3.85Å; F279-F372 AromaticContact CE1-CD2 3.71Å; F279-F372 HydrophobicContact CE1-CD2 3.71Å; F279-F372 HydrophobicContact CE1-CE1 4.25Å; F279-F372 HydrophobicContact CE1-CE2 4.11Å; F279-F372 AromaticContact CE1-CG 3.55Å; F279-F372 HydrophobicContact CE1-CG 3.55Å; F279-F372 HydrophobicContact CE1-CZ 4.37Å; F279-F372 HydrophobicContact CE2-CB 4.26Å; F279-F372 HydrophobicContact CG-CB 4.09Å; F279-F372 AromaticContact CG-CD2 3.64Å; F279-F372 HydrophobicContact CG-CD2 3.64Å; F279-F372 HydrophobicContact CG-CE2 4.36Å; F279-F372 HydrophobicContact CG-CG 4.02Å; F279-F372 HydrophobicContact CZ-CB 4.14Å; F279-F372 HydrophobicContact CZ-CG 4.18Å
280L78.5Confident78.4Confident2 Ų250 Ų501%0.0125%0.25CC..Hα-helixtrans-68.7-33178.1-61.1-179.5000112.9L276 L277 K278 V283 E284 F372 A484 F487 R488 I491L276-L280 WeakPolarHBondContact O-CG 3.36Å; L276-L280 PolarHBondContact O-N 2.91Å; L277-L280 PolarHBondContact O-N 2.98Å; L277-L280 VanDerWaalsContact O-N 3.11Å; K278-L280 VanDerWaalsContact C-N 3.32Å; K278-L280 PolarHBondContact O-N 3.47Å; L280-V283 PolarHBondContact O-N 2.78Å; L280-E284 WeakPolarHBondContact O-CB 3.46Å; L280-E284 PolarHBondContact O-N 3.39Å; L280-F372 HydrophobicContact CD2-CE2 4.06Å; L280-F372 HydrophobicContact CD2-CZ 4.08Å; L280-F372 HydrophobicContact CG-CE2 4.37Å; L280-A484 HydrophobicContact CD2-CB 4.42Å; L280-F487 HydrophobicContact CD1-CB 3.61Å; L280-F487 HydrophobicContact CD2-CB 3.72Å; L280-F487 HydrophobicContact CD2-CD2 4.3Å; L280-F487 HydrophobicContact CD2-CG 4.28Å; L280-F487 HydrophobicContact CG-CB 4.32Å; L280-R488 VanDerWaalsContact C-NH2 3.34Å; L280-R488 HydrophobicContact CB-CG 4.36Å; L280-R488 HydrophobicContact CD1-CB 4.41Å; L280-R488 HydrophobicContact CD1-CG 3.59Å; L280-R488 PolarHBondContact O-NH2 3Å; L280-R488 VanDerWaalsContact O-NH2 3.12Å; L280-I491 HydrophobicContact CD1-CD1 3.62Å
281D77.8Confident76.8Confident77 Ų7747.8 Ų47.841%0.41224%0.24SC..Hα-helixtrans-65.7-41.9172.2-71.5-14.7000111.7L277 K278 V283 E284 Q285 R488L277-D281 PolarHBondContact O-N 3.45Å; K278-D281 PolarHBondContact O-N 3.08Å; D281-V283 VanDerWaalsContact C-N 3.34Å; D281-V283 PolarHBondContact O-N 2.99Å; D281-E284 PolarHBondContact O-N 3.28Å; D281-Q285 WeakPolarHBondContact O-CB 3.4Å; D281-Q285 VanDerWaalsContact O-CG 3.28Å; D281-Q285 WeakPolarHBondContact O-CG 3.3Å; D281-Q285 PolarHBondContact O-N 2.9Å; D281-R488 IonicContact OD1-CZ 2.84Å; D281-R488 IonicContact OD1-NE 2.98Å; D281-R488 IonicContact OD1-NH2 2.83Å; D281-R488 PolarHBondContact OD1-NH2 3.45Å
282D69.6Low75.3Confident32 Ų3250 Ų5017%0.17125%0.248CC..Hα-helixtrans-61.5-43.1174.2-68-21.6000110.7K278 F279 E284 Q285 C286K278-D282 PolarHBondContact O-N 2.93Å; F279-D282 PolarHBondContact O-N 3.38Å; D282-E284 PolarHBondContact O-N 3.08Å; D282-Q285 PolarHBondContact O-N 3.03Å; D282-C286 WeakPolarHBondContact O-CB 3.34Å; D282-C286 PolarHBondContact O-N 2.96Å; D282-C286 PolarHBondContact O-SG 3.05Å
283V72.1Confident73.6Confident17 Ų1752 Ų5210%0.10326%0.257CS..Hα-helixtrans-61.1-43.6175.6171.50000111.9F279 L280 D281 C286 A287 L480 A484F279-V283 HydrophobicContact CD1-CG2 4.21Å; F279-V283 HydrophobicContact CE1-CG2 3.76Å; F279-V283 HydrophobicContact CE2-CG2 4.46Å; F279-V283 HydrophobicContact CZ-CG2 3.89Å; F279-V283 WeakPolarHBondContact O-CG2 3.32Å; F279-V283 PolarHBondContact O-N 3.3Å; L280-V283 PolarHBondContact O-N 2.78Å; D281-V283 VanDerWaalsContact C-N 3.34Å; D281-V283 PolarHBondContact O-N 2.99Å; V283-C286 WeakPolarHBondContact O-CB 3.36Å; V283-C286 PolarHBondContact O-N 3.36Å; V283-A287 PolarHBondContact O-N 3.48Å; V283-L480 HydrophobicContact CG1-CB 3.89Å; V283-L480 HydrophobicContact CG1-CD2 4.16Å; V283-L480 HydrophobicContact CG1-CG 4.46Å; V283-A484 HydrophobicContact CG1-CB 4.14Å
284E71.5Confident71.9Confident55 Ų5551.7 Ų51.726%0.25726%0.257SS..Hα-helixtrans-65.1-42.6178.1-173.760.3-137.500111.7L280 D281 D282 C286 A287 A288 R481 R488L280-E284 WeakPolarHBondContact O-CB 3.46Å; L280-E284 PolarHBondContact O-N 3.39Å; D281-E284 PolarHBondContact O-N 3.28Å; D282-E284 PolarHBondContact O-N 3.08Å; E284-C286 VanDerWaalsContact C-N 3.34Å; E284-C286 PolarHBondContact O-N 3.45Å; E284-A287 WeakPolarHBondContact O-CB 3.22Å; E284-A287 PolarHBondContact O-N 3.48Å; E284-A288 PolarHBondContact O-N 3.37Å; E284-R481 VanDerWaalsContact OE1-CD 3.25Å; E284-R481 WeakPolarHBondContact OE1-CD 3.38Å; E284-R481 WeakPolarHBondContact OE1-CG 3.49Å; E284-R481 IonicContact OE1-CZ 2.58Å; E284-R481 IonicContact OE1-NE 3.75Å; E284-R481 PolarHBondContact OE1-NE 3.44Å; E284-R481 WeakPolarHBondContact OE2-CG 3.24Å; E284-R488 IonicContact OE2-NH1 3.26Å
285Q69.4Low70.4Confident114 Ų11453.5 Ų53.553%0.53326%0.257SS..Hα-helixtrans-61.6-43.6175.2-72.6178.134.200111.4D281 D282 A287 A288 Q289D281-Q285 WeakPolarHBondContact O-CB 3.4Å; D281-Q285 VanDerWaalsContact O-CG 3.28Å; D281-Q285 WeakPolarHBondContact O-CG 3.3Å; D281-Q285 PolarHBondContact O-N 2.9Å; D282-Q285 PolarHBondContact O-N 3.03Å; Q285-A287 VanDerWaalsContact C-N 3.33Å; Q285-A287 PolarHBondContact O-N 2.97Å; Q285-A288 PolarHBondContact O-N 3.02Å; Q285-Q289 WeakPolarHBondContact O-CG 3.38Å; Q285-Q289 PolarHBondContact O-N 3.37Å
286C64.9Low68.9Low18 Ų1851.9 Ų51.912%0.12226%0.261CS..Hα-helixtrans-58.9-45174-73.50000111.4D282 V283 E284 A288 Q289 L290 A320D282-C286 WeakPolarHBondContact O-CB 3.34Å; D282-C286 PolarHBondContact O-N 2.96Å; D282-C286 PolarHBondContact O-SG 3.05Å; V283-C286 WeakPolarHBondContact O-CB 3.36Å; V283-C286 PolarHBondContact O-N 3.36Å; E284-C286 VanDerWaalsContact C-N 3.34Å; E284-C286 PolarHBondContact O-N 3.45Å; C286-A288 VanDerWaalsContact C-N 3.35Å; C286-A288 PolarHBondContact O-N 3.26Å; C286-Q289 PolarHBondContact O-N 3.32Å; C286-L290 WeakPolarHBondContact O-CG 3.5Å; C286-L290 PolarHBondContact O-N 3.06Å; C286-A320 WeakPolarHBondContact CB-O 3.37Å; C286-A320 PolarHBondContact SG-O 3.42Å
287A66Low67.3Low0 Ų054 Ų540%028%0.279CS..Hα-helixtrans-61.3-41.1176.200000112.4V283 E284 Q285 L290 E291 S477 L480 R481V283-A287 PolarHBondContact O-N 3.48Å; E284-A287 WeakPolarHBondContact O-CB 3.22Å; E284-A287 PolarHBondContact O-N 3.48Å; Q285-A287 VanDerWaalsContact C-N 3.33Å; Q285-A287 PolarHBondContact O-N 2.97Å; A287-L290 PolarHBondContact O-N 2.89Å; A287-E291 PolarHBondContact O-N 2.79Å; A287-S477 WeakPolarHBondContact O-CB 3.42Å; A287-S477 PolarHBondContact O-OG 2.96Å; A287-L480 HydrophobicContact CB-CB 4.16Å; A287-R481 HydrophobicContact CB-CG 3.64Å
288A67.9Low65.3Low31 Ų3157.4 Ų57.426%0.25629%0.292SS..Hα-helixtrans-66.4-39.6177.200000112.9E284 Q285 C286 E291 K292E284-A288 PolarHBondContact O-N 3.37Å; Q285-A288 PolarHBondContact O-N 3.02Å; C286-A288 VanDerWaalsContact C-N 3.35Å; C286-A288 PolarHBondContact O-N 3.26Å; A288-E291 PolarHBondContact O-N 2.65Å; A288-K292 WeakPolarHBondContact O-CG 3.46Å; A288-K292 PolarHBondContact O-N 3.25Å
289Q62Low63.6Low97 Ų9757.3 Ų57.345%0.45330%0.296SS..Hα-helixtrans-64.7-45.4175.4-71.9-177.84.600111.6Q285 C286 E291 K292 M293Q285-Q289 WeakPolarHBondContact O-CG 3.38Å; Q285-Q289 PolarHBondContact O-N 3.37Å; C286-Q289 PolarHBondContact O-N 3.32Å; Q289-E291 PolarHBondContact O-N 2.78Å; Q289-K292 PolarHBondContact O-N 2.99Å; Q289-M293 VanDerWaalsContact O-CG 3.25Å; Q289-M293 WeakPolarHBondContact O-CG 3.39Å; Q289-M293 PolarHBondContact O-N 3.43Å
290L62.3Low61.6Low6 Ų660.4 Ų60.43%0.03132%0.321CS..Hα-helixtrans-56-38.3176.1-74.9171.5000112.2C286 A287 N294 V317 A320 V476 L480C286-L290 WeakPolarHBondContact O-CG 3.5Å; C286-L290 PolarHBondContact O-N 3.06Å; A287-L290 PolarHBondContact O-N 2.89Å; L290-N294 PolarHBondContact O-N 2.81Å; L290-N294 VanDerWaalsContact O-N 3.09Å; L290-V317 HydrophobicContact CD2-CG2 3.93Å; L290-A320 HydrophobicContact CD2-CB 4.2Å; L290-A320 HydrophobicContact CG-CB 4.32Å; L290-V476 HydrophobicContact CD1-CB 4.27Å; L290-V476 HydrophobicContact CD1-CG1 3.85Å; L290-L480 HydrophobicContact CD1-CD1 4.28Å
291E61.8Low59.9Low50 Ų5064.7 Ų64.723%0.23435%0.351CS..Hα-helixtrans-71.6-45177.9-165-168.1148.100112.9A287 A288 Q289 M293 N294 K295 R481A287-E291 PolarHBondContact O-N 2.79Å; A288-E291 PolarHBondContact O-N 2.65Å; Q289-E291 PolarHBondContact O-N 2.78Å; E291-M293 PolarHBondContact O-N 2.87Å; E291-N294 WeakPolarHBondContact O-CB 3.46Å; E291-N294 PolarHBondContact O-N 3.17Å; E291-N294 VanDerWaalsContact O-N 3.08Å; E291-K295 PolarHBondContact O-N 3.24Å; E291-K295 WeakPolarHBondContact OE1-CE 3.31Å; E291-K295 IonicContact OE1-NZ 2.78Å; E291-K295 PolarHBondContact OE1-NZ 2.92Å; E291-R481 IonicContact OE2-CZ 2.6Å; E291-R481 IonicContact OE2-NH1 3.18Å; E291-R481 PolarHBondContact OE2-NH1 3.13Å; E291-R481 IonicContact OE2-NH2 2.9Å; E291-R481 PolarHBondContact OE2-NH2 3Å
292K63.5Low58Low157 Ų15767.8 Ų67.868%0.68337%0.366SS*.Hα-helixtrans-56.4-42.4175.1-75.5178.5-178.7178.30111.1A288 Q289 K295 G296A288-K292 WeakPolarHBondContact O-CG 3.46Å; A288-K292 PolarHBondContact O-N 3.25Å; Q289-K292 PolarHBondContact O-N 2.99Å; K292-K295 PolarHBondContact O-N 2.9Å; K292-G296 PolarHBondContact O-N 2.9Å
293M55.7Low56.5Low44 Ų4471.7 Ų71.722%0.21739%0.391CS..Hα-helixtrans-68.2-33.4177.2-67.5174.964.700113.7Q289 E291 A297 I316 K473Q289-M293 VanDerWaalsContact O-CG 3.25Å; Q289-M293 WeakPolarHBondContact O-CG 3.39Å; Q289-M293 PolarHBondContact O-N 3.43Å; E291-M293 PolarHBondContact O-N 2.87Å; M293-A297 WeakPolarHBondContact O-CB 3.44Å; M293-A297 PolarHBondContact O-N 3.15Å; M293-I316 HydrophobicContact CE-CB 3.58Å; M293-I316 HydrophobicContact CE-CD1 3.24Å; M293-I316 HydrophobicContact CE-CG1 3.97Å; M293-I316 HydrophobicContact CE-CG2 3.46Å; M293-I316 VanDerWaalsContact CE-CG2 3.46Å; M293-I316 HydrophobicContact SD-CB 4.11Å; M293-I316 HydrophobicContact SD-CD1 4.17Å; M293-I316 HydrophobicContact SD-CG2 3.25Å; M293-I316 WeakPolarHBondContact SD-CG2 3.41Å; M293-K473 HydrophobicContact CB-CD 4.41Å
294N57.4Low54.5Low24 Ų2476 Ų7613%0.12842%0.423CS..Hα-helixtrans-66.6-43.1173.4-175.462.9000111.2L290 E291 A297 K298 K473 T474L290-N294 PolarHBondContact O-N 2.81Å; L290-N294 VanDerWaalsContact O-N 3.09Å; E291-N294 WeakPolarHBondContact O-CB 3.46Å; E291-N294 PolarHBondContact O-N 3.17Å; E291-N294 VanDerWaalsContact O-N 3.08Å; N294-A297 PolarHBondContact O-N 2.92Å; N294-K298 WeakPolarHBondContact O-CG 3.37Å; N294-K298 PolarHBondContact O-N 3.27Å; N294-K473 HydrophobicContact CB-CB 4.1Å; N294-T474 PolarHBondContact ND2-OG1 3Å
295K59.5Low52.7Low116 Ų11678.8 Ų78.850%0.50445%0.448SS..Hα-helixtrans-61.7-46.7174.3-74.5170.1169.7163.20111.2E291 K292 A297 K298 I299E291-K295 PolarHBondContact O-N 3.24Å; E291-K295 WeakPolarHBondContact OE1-CE 3.31Å; E291-K295 IonicContact OE1-NZ 2.78Å; E291-K295 PolarHBondContact OE1-NZ 2.92Å; K292-K295 PolarHBondContact O-N 2.9Å; K295-A297 PolarHBondContact O-N 3.1Å; K295-K298 PolarHBondContact O-N 2.95Å; K295-I299 WeakPolarHBondContact O-CD1 3.36Å; K295-I299 VanDerWaalsContact O-CG1 3.24Å; K295-I299 WeakPolarHBondContact O-CG1 3.4Å; K295-I299 PolarHBondContact O-N 2.95Å
296G55.3Low51Low41 Ų4178.3 Ų78.342%0.42346%0.457SS..Hα-helixtrans-59.9-42.2176.200000113.5K292 I299 S300K292-G296 PolarHBondContact O-N 2.9Å; G296-I299 PolarHBondContact O-N 3.41Å; G296-S300 PolarHBondContact O-N 3.16Å; G296-S300 VanDerWaalsContact O-N 3.1Å
297A51.6Low49.4Very low45 Ų4584.4 Ų84.437%0.37249%0.493SS..Hα-helixtrans-68-36.2175.800000113.2M293 N294 K295 S300 S301M293-A297 WeakPolarHBondContact O-CB 3.44Å; M293-A297 PolarHBondContact O-N 3.15Å; N294-A297 PolarHBondContact O-N 2.92Å; K295-A297 PolarHBondContact O-N 3.1Å; A297-S300 PolarHBondContact O-OG 3.45Å; A297-S301 PolarHBondContact O-N 2.94Å
298K44.2Very low48Very low125 Ų12588.1 Ų88.154%0.54353%0.531SS..Hα-helixtrans-68.8-36.9174.4-76.4-176178.1-171.60111.9N294 K295 S301N294-K298 WeakPolarHBondContact O-CG 3.37Å; N294-K298 PolarHBondContact O-N 3.27Å; K295-K298 PolarHBondContact O-N 2.95Å; K298-S301 PolarHBondContact O-N 3.22Å; K298-S301 PolarHBondContact O-OG 3Å
299I45.1Very low46.5Very low126 Ų12691.3 Ų91.365%0.64656%0.558SS**Hα-helixtrans-67.4-39.6177.2-66.8163.6000110.8K295 G296 S301 I302K295-I299 WeakPolarHBondContact O-CD1 3.36Å; K295-I299 VanDerWaalsContact O-CG1 3.24Å; K295-I299 WeakPolarHBondContact O-CG1 3.4Å; K295-I299 PolarHBondContact O-N 2.95Å; G296-I299 PolarHBondContact O-N 3.41Å; I299-S301 PolarHBondContact O-N 3.4Å; I299-I302 PolarHBondContact O-N 3.33Å
300S38.7Very low45.2Very low91 Ų9192.1 Ų92.164%0.63658%0.581SS**THydrogen-bonded Turntrans-68.8-1217790.90000114G296 A297G296-S300 PolarHBondContact O-N 3.16Å; G296-S300 VanDerWaalsContact O-N 3.1Å; A297-S300 PolarHBondContact O-OG 3.45Å
301S41.1Very low43.7Very low93 Ų9395 Ų9565%0.6561%0.612SS**THydrogen-bonded Turntrans-89-6.717868.60000115.1A297 K298 I299A297-S301 PolarHBondContact O-N 2.94Å; K298-S301 PolarHBondContact O-N 3.22Å; K298-S301 PolarHBondContact O-OG 3Å; I299-S301 PolarHBondContact O-N 3.4Å
302I38.7Very low42.4Very low142 Ų14295 Ų9573%0.72863%0.626SS**SBendtrans-102.8-1.4-176.6-60.2176.2000112.2I299I299-I302 PolarHBondContact O-N 3.33Å
303T38.5Very low41.1Very low113 Ų11390.7 Ų90.769%0.69361%0.613SS**SBendtrans-141.5125.8174.2-55.60000111.4
304S29.4Very low40.2Very low109 Ų10993.5 Ų93.576%0.76263%0.628SS**  trans83.3105177.6780000116.4
305S34.4Very low39.4Very low112 Ų11296.2 Ų96.278%0.78365%0.649SS**  trans-51.2129.415343.50000111.3
306S33.7Very low38.7Very low104 Ų10493.7 Ų93.773%0.72764%0.64SS**SBendtrans70.7127.4160.464.40000120.4
307V30.7Very low37.9Very low147 Ų14792 Ų9289%0.89162%0.621SS**  trans101.2103.5153.8-166.10000116.5
308G37.3Very low37.3Very low77 Ų7790.6 Ų90.679%0.79461%0.611SS**  trans83.274.2139.900000118.4
309A35.9Very low37.1Very low99 Ų9989 Ų8982%0.81861%0.608SS**  trans-151.948.3156.900000112.5G311A309-G311 PolarHBondContact O-N 2.9Å
310A34.4Very low36.9Very low113 Ų11383.5 Ų83.593%0.93458%0.582SS**  trans-89.286.116300000108.1
311G29.9Very low37Very low67 Ų6780.4 Ų80.469%0.69156%0.558SS**SBendtrans-156.9-34.2-179.800000117.1A309A309-G311 PolarHBondContact O-N 2.9Å
312G34.8Very low37Very low50 Ų5077.7 Ų77.752%0.51554%0.536SS..SBendtrans-92.2-5.8-172.500000116.6I316G312-I316 WeakPolarHBondContact O-CD1 3.32Å
313V35.9Very low37Very low67 Ų6772.5 Ų72.541%0.40651%0.511SS..THydrogen-bonded Turntrans-92-24.1-1591800000114.2
314L36.9Very low37.2Very low102 Ų10271.7 Ų71.753%0.53451%0.506SS..THydrogen-bonded Turntrans-82.2-35.4-177.3-91.296.7000114.4I316 K470L314-I316 PolarHBondContact O-N 3.04Å; L314-K470 VanDerWaalsContact CD2-CE 3.48Å
315S41.6Very low37.2Very low82 Ų8270.5 Ų70.557%0.57349%0.494SS*.Hα-helixtrans-68.7-34.1-174.2-64.90000113.1V317 G318 L319S315-V317 VanDerWaalsContact C-N 3.3Å; S315-V317 PolarHBondContact O-N 3.08Å; S315-G318 PolarHBondContact O-N 3.37Å; S315-L319 WeakPolarHBondContact O-CB 3.49Å; S315-L319 WeakPolarHBondContact O-CD1 3.3Å; S315-L319 WeakPolarHBondContact O-CG 3.35Å; S315-L319 PolarHBondContact O-N 3.24Å
316I43.8Very low36.9Very low62 Ų6268.5 Ų68.532%0.31849%0.485SS..Hα-helixtrans-76.7-20.5-166.3-58.5167.7000112.5M293 G312 L314 L319 A320M293-I316 HydrophobicContact CE-CB 3.58Å; M293-I316 HydrophobicContact CE-CD1 3.24Å; M293-I316 HydrophobicContact CE-CG1 3.97Å; M293-I316 HydrophobicContact CE-CG2 3.46Å; M293-I316 VanDerWaalsContact CE-CG2 3.46Å; M293-I316 HydrophobicContact SD-CB 4.11Å; M293-I316 HydrophobicContact SD-CD1 4.17Å; M293-I316 HydrophobicContact SD-CG2 3.25Å; M293-I316 WeakPolarHBondContact SD-CG2 3.41Å; G312-I316 WeakPolarHBondContact O-CD1 3.32Å; L314-I316 PolarHBondContact O-N 3.04Å; I316-L319 CarbonylContact O-C 3.4Å; I316-L319 PolarHBondContact O-N 3.2Å; I316-A320 VanDerWaalsContact O-CB 3.29Å; I316-A320 WeakPolarHBondContact O-CB 3.34Å; I316-A320 PolarHBondContact O-N 3.22Å
317V38.9Very low36.6Very low5 Ų567 Ų673%0.0349%0.486CS..Hα-helixtrans-88-35.1178.3171.20000111.4L290 S315 L319 A320 S465 A469L290-V317 HydrophobicContact CD2-CG2 3.93Å; S315-V317 VanDerWaalsContact C-N 3.3Å; S315-V317 PolarHBondContact O-N 3.08Å; V317-L319 PolarHBondContact O-N 2.91Å; V317-A320 PolarHBondContact O-N 2.7Å; V317-S465 WeakPolarHBondContact CG1-O 3.49Å; V317-A469 HydrophobicContact CB-CB 3.43Å; V317-A469 VanDerWaalsContact CB-CB 3.43Å; V317-A469 HydrophobicContact CG1-CB 3.17Å; V317-A469 HydrophobicContact CG2-CB 3.11Å
318G39.6Very low36.5Very low16 Ų1669.3 Ų69.317%0.16549%0.492CS..Hα-helixtrans-59.9-27.6164.100000111.9S315 I322S315-G318 PolarHBondContact O-N 3.37Å; G318-I322 WeakPolarHBondContact O-CG1 3.41Å
319L40.3Very low36.3Very low92 Ų9270.4 Ų70.448%0.48249%0.488SS..Hα-helixtrans-86.3-32176.5-85.6154.4000114.8S315 I316 V317 L321 I322S315-L319 WeakPolarHBondContact O-CB 3.49Å; S315-L319 WeakPolarHBondContact O-CD1 3.3Å; S315-L319 WeakPolarHBondContact O-CG 3.35Å; S315-L319 PolarHBondContact O-N 3.24Å; I316-L319 CarbonylContact O-C 3.4Å; I316-L319 PolarHBondContact O-N 3.2Å; V317-L319 PolarHBondContact O-N 2.91Å; L319-L321 PolarHBondContact O-N 3.47Å; L319-I322 HydrophobicContact CD2-CD1 3.76Å; L319-I322 HydrophobicContact CG-CD1 4.1Å; L319-I322 WeakPolarHBondContact O-CB 3.21Å; L319-I322 PolarHBondContact O-N 3.49Å
320A40.1Very low36.4Very low10 Ų1071.3 Ų71.38%0.08348%0.483CS..Hα-helixtrans-70.5-10.9-179.500000113.6C286 L290 I316 V317C286-A320 WeakPolarHBondContact CB-O 3.37Å; C286-A320 PolarHBondContact SG-O 3.42Å; L290-A320 HydrophobicContact CD2-CB 4.2Å; L290-A320 HydrophobicContact CG-CB 4.32Å; I316-A320 VanDerWaalsContact O-CB 3.29Å; I316-A320 WeakPolarHBondContact O-CB 3.34Å; I316-A320 PolarHBondContact O-N 3.22Å; V317-A320 PolarHBondContact O-N 2.7Å
321L40.8Very low36.4Very low27 Ų2768.2 Ų68.214%0.14146%0.462CS..THydrogen-bonded Turntrans-113.38171.6-67.4171.8000112.9L319 A365 F369 I461 S465L319-L321 PolarHBondContact O-N 3.47Å; L321-A365 VanDerWaalsContact O-CB 3.28Å; L321-A365 WeakPolarHBondContact O-CB 3.25Å; L321-F369 HydrophobicContact CD2-CE2 4.42Å; L321-I461 HydrophobicContact CD1-CG2 3.68Å; L321-I461 WeakPolarHBondContact CD1-O 3.35Å; L321-I461 HydrophobicContact CD2-CG2 3.76Å; L321-I461 HydrophobicContact CG-CG2 4.3Å; L321-S465 WeakPolarHBondContact CD1-OG 3.28Å
322I41.8Very low36.5Very low36 Ų3672.9 Ų72.919%0.18547%0.47CS..SBendtrans-78.2137167.8-60.5-178.5000107.1G318 L319 V324 Q361G318-I322 WeakPolarHBondContact O-CG1 3.41Å; L319-I322 HydrophobicContact CD2-CD1 3.76Å; L319-I322 HydrophobicContact CG-CD1 4.1Å; L319-I322 WeakPolarHBondContact O-CB 3.21Å; L319-I322 PolarHBondContact O-N 3.49Å; I322-V324 PolarHBondContact O-N 3.05Å; I322-Q361 HydrophobicContact CD1-CB 4.49Å; I322-Q361 HydrophobicContact CD1-CG 3.87Å
323P38.1Very low36.7Very low33 Ų3377.1 Ų77.121%0.21449%0.486CS..  trans-60.1126171.3-16.929.2000111.1T325 V368P323-T325 HydrophobicContact CB-CG2 4.49Å; P323-T325 WeakPolarHBondContact CB-OG1 3.42Å; P323-T325 PolarHBondContact O-N 3.45Å; P323-V368 HydrophobicContact CB-CB 4.08Å; P323-V368 HydrophobicContact CB-CG1 4.1Å; P323-V368 HydrophobicContact CB-CG2 3.53Å; P323-V368 HydrophobicContact CG-CB 3.55Å; P323-V368 HydrophobicContact CG-CG1 4.07Å; P323-V368 HydrophobicContact CG-CG2 3.12Å
324V42.3Very low36.7Very low96 Ų9680.8 Ų80.858%0.58250%0.502SS*.  trans-79.558.8161.5-172.90000108I322I322-V324 PolarHBondContact O-N 3.05Å
325T30.8Very low36.2Very low83 Ų8380.6 Ų80.651%0.50952%0.515SS..  trans-132.767.2-176.456.20000112.4P323P323-T325 HydrophobicContact CB-CG2 4.49Å; P323-T325 WeakPolarHBondContact CB-OG1 3.42Å; P323-T325 PolarHBondContact O-N 3.45Å
326A27.7Very low35.5Very low71 Ų7180.3 Ų80.359%0.58753%0.525SS*.SBendtrans-150.2127.5144.200000107.5L328A326-L328 PolarHBondContact O-N 2.95Å
327G27.7Very low34.8Very low73 Ų7384 Ų8475%0.75355%0.55SS**THydrogen-bonded Turntrans-45.9137.2-173.900000113.7S329G327-S329 PolarHBondContact O-N 3.37Å
328L29Very low34.2Very low194 Ų19490.4 Ų90.4100%1.01659%0.59SS**THydrogen-bonded Turntrans49.310.4166-66.7174.5000119.5A326A326-L328 PolarHBondContact O-N 2.95Å
329S33.2Very low34.1Very low101 Ų10198.8 Ų98.871%0.70663%0.627SS**THydrogen-bonded Turntrans-125.8-9.1-171-174.20000117.2G327G327-S329 PolarHBondContact O-N 3.37Å
330V37.4Very low33.5Very low117 Ų11797.6 Ų97.671%0.70964%0.637SS**SBendtrans-1278.5175.7-166.30000112.8
331G33.2Very low33.1Very low49 Ų49103.5 Ų103.551%0.50567%0.672SS.*  trans-87.60.1176.700000115.6
332L32.4Very low32.6Very low164 Ų164108.1 Ų108.186%0.85970%0.701SS**  trans-107.667.1178.6-126.186.6000111.7
333T38.5Very low32Very low140 Ų140112.3 Ų112.386%0.85973%0.734SS**  trans-126.940.7147-45.90000108.9
334I36Very low31.3Very low143 Ų143114.5 Ų114.573%0.73376%0.762SS**  trans-99.585.6158.5-58.4175.5000105.6
335A28.2Very low30.7Very low98 Ų98114.2 Ų114.281%0.8177%0.77SS**  trans-169.5107.715500000107.7
336G26Very low30.5Very low76 Ų76118.2 Ų118.278%0.78479%0.788SS**  trans-173.612.1-179.700000117
337V29.8Very low30.5Very low140 Ų140120.5 Ų120.585%0.84880%0.8SS**  trans-145.589.2153-170.80000108
338T25.7Very low30.5Very low139 Ų139124.5 Ų124.585%0.85380%0.803SS**  trans-140.4118.814849.90000109.1
339M38Very low30.3Very low193 Ų193121.5 Ų121.595%0.95179%0.792SS**  trans-58.3134.4163-67.4161.66700108.8
340G27.2Very low30.1Very low67 Ų67121.7 Ų121.769%0.69179%0.79SS**  trans129.693160.300000117.2
341V32Very low29.8Very low134 Ų134122.9 Ų122.981%0.81280%0.797SS**  trans36.8108.7140.7-129.20000119.8
342T30.8Very low29.5Very low124 Ų124127 Ų12776%0.76181%0.807SS**  162.5117.8102.343.50000112.6
343S27.8Very low29.2Very low124 Ų124125.2 Ų125.287%0.86780%0.803SS**  trans54.3123.5148.465.60000123
344G24.7Very low28.9Very low78 Ų78126.5 Ų126.580%0.80480%0.799SS**  trans143.5112.1146.600000114.6
345A28.5Very low28.8Very low91 Ų91126.6 Ų126.675%0.75281%0.806SS**  trans-68.8161.5-172.700000115.4
346N26.3Very low29.2Very low167 Ų167125.2 Ų125.289%0.89380%0.801SS**  trans94.6111.8-179.2-53.3-16.3000112.4
347S27.6Very low29.9Very low118 Ų118125.9 Ų125.983%0.82579%0.79SS**  cis-150.1124.637.6-176.10000110.5
348L27.6Very low31Very low157 Ų157123.5 Ų123.582%0.82277%0.773SS**  trans-59.3164.7158.6-76.9153.3000110.2
349V25.8Very low32.1Very low131 Ų131121.2 Ų121.279%0.79476%0.762SS**  trans87.8113.6166.1-169.40000112.6
350T29.5Very low32.6Very low106 Ų106114.3 Ų114.365%0.6573%0.733SS**  cis-154.7110.828.1-360000109.4
351T30.4Very low33.6Very low142 Ų142114.4 Ų114.487%0.87172%0.715SS**SBendtrans-97.291.9154.2-49.90000105.2
352L26.7Very low34.4Very low134 Ų134111 Ų11170%0.70269%0.691SS**  trans165.1102159.9-92.6155.2000109.1
353T26.9Very low35.5Very low127 Ų127111.5 Ų111.578%0.77968%0.682SS**  trans-144.493.3141.7-35.90000107.1
354E31.1Very low36.7Very low167 Ų167110.6 Ų110.678%0.7866%0.663SS**  trans-63.8137.5152.6-75.1-179.5141.300107.6
355V34.5Very low38.1Very low146 Ų146107.1 Ų107.189%0.88563%0.626SS**SBendtrans70.998.3174.2-167.70000115.1
356G35.3Very low39.5Very low68 Ų68105 Ų10570%0.70160%0.602SS**  trans144.465.2164.800000114.6N358G356-N358 PolarHBondContact O-N 3.45Å; G356-N358 VanDerWaalsContact O-N 3.08Å
357V42.3Very low41.1Very low91 Ų91102.2 Ų102.255%0.55258%0.584SS**  trans-64.8111.6163.6172.50000107.1L466V357-L466 HydrophobicContact CB-CD2 4.2Å; V357-L466 HydrophobicContact CG1-CD1 4.4Å; V357-L466 HydrophobicContact CG1-CD2 4.19Å; V357-L466 HydrophobicContact CG2-CD1 3.72Å; V357-L466 HydrophobicContact CG2-CD2 3.89Å; V357-L466 HydrophobicContact CG2-CG 4.47Å
358N51.8Low42.8Very low90 Ų9098 Ų9848%0.48155%0.553SS.*  trans-73.1135.2-167.5-169.2-2.3000111G356 S360 Q361G356-N358 PolarHBondContact O-N 3.45Å; G356-N358 VanDerWaalsContact O-N 3.08Å; N358-S360 WeakPolarHBondContact ND2-CB 3.48Å; N358-S360 PolarHBondContact O-N 2.97Å; N358-S360 PolarHBondContact OD1-N 3.4Å; N358-Q361 PolarHBondContact O-N 3.23Å; N358-Q361 VanDerWaalsContact O-N 3.08Å
359S49.8Very low44.7Very low91 Ų9191.9 Ų91.964%0.63652%0.52SS*.Hα-helixtrans-52-24.6169.855.50000112.7K363S359-K363 WeakPolarHBondContact O-CB 3.29Å; S359-K363 PolarHBondContact O-N 3.34Å
360S46.8Very low46.5Very low47 Ų4786.4 Ų86.433%0.32949%0.49SS..Hα-helixtrans-62-38.6175.9-172.70000114.4N358 K364N358-S360 WeakPolarHBondContact ND2-CB 3.48Å; N358-S360 PolarHBondContact O-N 2.97Å; N358-S360 PolarHBondContact OD1-N 3.4Å; S360-K364 WeakPolarHBondContact O-CG 3.46Å; S360-K364 PolarHBondContact O-N 2.93Å
361Q48.4Very low48.6Very low69 Ų6986.9 Ų86.932%0.32248%0.483SS..Hα-helixtrans-73-41.4179.3-72.3179.1-25.200111.2I322 N358 K363 K364 A365I322-Q361 HydrophobicContact CD1-CB 4.49Å; I322-Q361 HydrophobicContact CD1-CG 3.87Å; N358-Q361 PolarHBondContact O-N 3.23Å; N358-Q361 VanDerWaalsContact O-N 3.08Å; Q361-K363 VanDerWaalsContact C-N 3.35Å; Q361-K363 PolarHBondContact O-N 3.34Å; Q361-K364 PolarHBondContact O-N 3.42Å; Q361-A365 PolarHBondContact O-N 3.07Å; Q361-A365 VanDerWaalsContact O-N 3.09Å
362Q49.6Very low50.9Low64 Ų6480.5 Ų80.530%0.29944%0.443SS..Hα-helixtrans-60.6-43.3172.6174.1165.934.100111.7K364 A365 N366 A462Q362-K364 PolarHBondContact O-N 2.95Å; Q362-A365 PolarHBondContact O-N 2.9Å; Q362-N366 WeakPolarHBondContact O-CB 3.31Å; Q362-N366 PolarHBondContact O-N 3.04Å; Q362-N366 PolarHBondContact O-OD1 3.13Å; Q362-N366 VanDerWaalsContact O-OD1 3.11Å; Q362-A462 HydrophobicContact CB-CB 4Å; Q362-A462 HydrophobicContact CG-CB 3.53Å
363K53Low53.2Low133 Ų13378 Ų7858%0.57843%0.425SS*.Hα-helixtrans-60.3-44177.9-169.7-177.6178.8-169.60112.2S359 Q361 N366 E367S359-K363 WeakPolarHBondContact O-CB 3.29Å; S359-K363 PolarHBondContact O-N 3.34Å; Q361-K363 VanDerWaalsContact C-N 3.35Å; Q361-K363 PolarHBondContact O-N 3.34Å; K363-N366 WeakPolarHBondContact O-CB 3.24Å; K363-N366 PolarHBondContact O-N 3.49Å; K363-E367 WeakPolarHBondContact CE-OE1 3.2Å; K363-E367 VanDerWaalsContact O-CG 3.31Å; K363-E367 WeakPolarHBondContact O-CG 3.49Å; K363-E367 PolarHBondContact O-N 2.91Å
364K54.4Low55.7Low106 Ų10677.2 Ų77.246%0.46141%0.413SS..Hα-helixtrans-67-40.4178.7-71.7177.6-178.9-173.50113.3S360 Q361 Q362 N366 E367 V368S360-K364 WeakPolarHBondContact O-CG 3.46Å; S360-K364 PolarHBondContact O-N 2.93Å; Q361-K364 PolarHBondContact O-N 3.42Å; Q362-K364 PolarHBondContact O-N 2.95Å; K364-N366 VanDerWaalsContact C-N 3.33Å; K364-E367 PolarHBondContact O-N 2.8Å; K364-V368 PolarHBondContact O-N 2.97Å
365A54Low58.2Low4 Ų469.7 Ų69.73%0.03338%0.377CS..Hα-helixtrans-61.2-45.2173.700000110.6L321 Q361 Q362 E367 V368 F369L321-A365 VanDerWaalsContact O-CB 3.28Å; L321-A365 WeakPolarHBondContact O-CB 3.25Å; Q361-A365 PolarHBondContact O-N 3.07Å; Q361-A365 VanDerWaalsContact O-N 3.09Å; Q362-A365 PolarHBondContact O-N 2.9Å; A365-E367 PolarHBondContact O-N 3.45Å; A365-V368 PolarHBondContact O-N 3.11Å; A365-F369 WeakPolarHBondContact O-CD2 3.43Å; A365-F369 PolarHBondContact O-N 2.93Å
366N57Low60.5Low48 Ų4862.7 Ų62.726%0.25734%0.335SS..Hα-helixtrans-61.6-41.8177.1-65.8-0.1000112.4Q362 K363 K364 V368 G370 I458Q362-N366 WeakPolarHBondContact O-CB 3.31Å; Q362-N366 PolarHBondContact O-N 3.04Å; Q362-N366 PolarHBondContact O-OD1 3.13Å; Q362-N366 VanDerWaalsContact O-OD1 3.11Å; K363-N366 WeakPolarHBondContact O-CB 3.24Å; K363-N366 PolarHBondContact O-N 3.49Å; K364-N366 VanDerWaalsContact C-N 3.33Å; N366-V368 VanDerWaalsContact C-N 3.31Å; N366-V368 PolarHBondContact O-N 3.01Å; N366-G370 WeakPolarHBondContact O-CA 3.35Å; N366-G370 PolarHBondContact O-N 3.37Å; N366-I458 HydrophobicContact CB-CG2 3.55Å; N366-I458 WeakPolarHBondContact OD1-CG2 3.23Å; N366-I458 PolarHBondContact OD1-O 3.3Å
367E60.1Low62.8Low107 Ų10762.2 Ų62.250%0.532%0.315SS..Hα-helixtrans-60.2-40.5177.4-77.1166.7-174.600111.8K363 K364 A365 K371K363-E367 WeakPolarHBondContact CE-OE1 3.2Å; K363-E367 VanDerWaalsContact O-CG 3.31Å; K363-E367 WeakPolarHBondContact O-CG 3.49Å; K363-E367 PolarHBondContact O-N 2.91Å; K364-E367 PolarHBondContact O-N 2.8Å; A365-E367 PolarHBondContact O-N 3.45Å; E367-K371 WeakPolarHBondContact O-CB 3.47Å; E367-K371 PolarHBondContact O-N 2.86Å
368V63.9Low64.9Low31 Ų3162.1 Ų62.119%0.18831%0.307CS..Hα-helixtrans-81.6-39.1-177.3171.70000113.5F279 P323 K364 A365 N366 G370 K371 F372F279-V368 HydrophobicContact CD2-CG1 3.92Å; F279-V368 HydrophobicContact CE2-CG1 3.78Å; P323-V368 HydrophobicContact CB-CB 4.08Å; P323-V368 HydrophobicContact CB-CG1 4.1Å; P323-V368 HydrophobicContact CB-CG2 3.53Å; P323-V368 HydrophobicContact CG-CB 3.55Å; P323-V368 HydrophobicContact CG-CG1 4.07Å; P323-V368 HydrophobicContact CG-CG2 3.12Å; K364-V368 PolarHBondContact O-N 2.97Å; A365-V368 PolarHBondContact O-N 3.11Å; N366-V368 VanDerWaalsContact C-N 3.31Å; N366-V368 PolarHBondContact O-N 3.01Å; V368-G370 VanDerWaalsContact C-N 3.26Å; V368-G370 PolarHBondContact O-N 3.34Å; V368-K371 PolarHBondContact O-N 3.44Å; V368-F372 PolarHBondContact O-N 2.95Å
369F66.7Low66.6Low27 Ų2757.8 Ų57.812%0.11828%0.284CS..Hα-helixtrans-62.7-37.7168.3-87.2-81.4000111.4F279 L321 A365 F372 Y373 I461F279-F369 HydrophobicContact CE1-CD1 4.4Å; F279-F369 HydrophobicContact CE1-CE1 4.14Å; F279-F369 AromaticContact CZ-CD1 3.68Å; F279-F369 HydrophobicContact CZ-CD1 3.68Å; F279-F369 HydrophobicContact CZ-CD2 4.49Å; F279-F369 AromaticContact CZ-CE1 3.5Å; F279-F369 HydrophobicContact CZ-CE1 3.5Å; F279-F369 HydrophobicContact CZ-CE2 4.32Å; F279-F369 HydrophobicContact CZ-CG 4.19Å; F279-F369 AromaticContact CZ-CZ 3.83Å; F279-F369 HydrophobicContact CZ-CZ 3.83Å; L321-F369 HydrophobicContact CD2-CE2 4.42Å; A365-F369 WeakPolarHBondContact O-CD2 3.43Å; A365-F369 PolarHBondContact O-N 2.93Å; F369-F372 PolarHBondContact O-N 2.86Å; F369-Y373 WeakPolarHBondContact O-CB 3.33Å; F369-Y373 PolarHBondContact O-N 3.08Å; F369-I461 HydrophobicContact CD1-CD1 3.98Å; F369-I461 HydrophobicContact CD2-CD1 4.43Å; F369-I461 HydrophobicContact CD2-CG2 4.44Å; F369-I461 HydrophobicContact CE1-CD1 3.71Å; F369-I461 HydrophobicContact CE2-CD1 4.22Å; F369-I461 HydrophobicContact CE2-CG2 3.8Å; F369-I461 HydrophobicContact CG-CD1 4.33Å; F369-I461 HydrophobicContact CZ-CD1 3.86Å; F369-I461 HydrophobicContact CZ-CG2 4.09Å
370G64.6Low68.3Low16 Ų1654.5 Ų54.517%0.16526%0.258CS..Hα-helixtrans-59-47.1172.600000111.4N366 V368 F372 Y373 E374N366-G370 WeakPolarHBondContact O-CA 3.35Å; N366-G370 PolarHBondContact O-N 3.37Å; V368-G370 VanDerWaalsContact C-N 3.26Å; V368-G370 PolarHBondContact O-N 3.34Å; G370-F372 PolarHBondContact O-N 3Å; G370-Y373 WeakPolarHBondContact O-CB 3.13Å; G370-Y373 PolarHBondContact O-N 3.18Å; G370-E374 WeakPolarHBondContact O-CB 3.43Å; G370-E374 WeakPolarHBondContact O-CG 3.32Å; G370-E374 PolarHBondContact O-N 3.2Å
371K73.1Confident70.1Confident117 Ų11755.5 Ų55.551%0.50926%0.26SS..Hα-helixtrans-62.5-43175.1-173.3177.2179.4-1790113E367 V368 Y373 E374 D375E367-K371 WeakPolarHBondContact O-CB 3.47Å; E367-K371 PolarHBondContact O-N 2.86Å; V368-K371 PolarHBondContact O-N 3.44Å; K371-Y373 VanDerWaalsContact C-N 3.34Å; K371-E374 PolarHBondContact O-N 3.09Å; K371-D375 WeakPolarHBondContact O-CB 3.47Å; K371-D375 PolarHBondContact O-N 3.25Å
372F78Confident72Confident7 Ų752.7 Ų52.73%0.03125%0.248CC..Hα-helixtrans-59.8-46.4174.6170.4-98.3000111.2L276 F279 L280 V368 F369 G370 D375 F376 F453 F487L276-F372 HydrophobicContact CB-CE2 4.41Å; L276-F372 HydrophobicContact CD2-CD2 3.55Å; L276-F372 HydrophobicContact CD2-CE2 3.57Å; L276-F372 HydrophobicContact CD2-CG 4.47Å; L276-F372 HydrophobicContact CD2-CZ 4.48Å; F279-F372 HydrophobicContact CB-CD2 3.96Å; F279-F372 HydrophobicContact CD1-CB 3.99Å; F279-F372 HydrophobicContact CD1-CD1 4.16Å; F279-F372 AromaticContact CD1-CD2 3.13Å; F279-F372 HydrophobicContact CD1-CD2 3.13Å; F279-F372 HydrophobicContact CD1-CE1 4.49Å; F279-F372 AromaticContact CD1-CE2 3.54Å; F279-F372 HydrophobicContact CD1-CE2 3.54Å; F279-F372 AromaticContact CD1-CG 3.48Å; F279-F372 HydrophobicContact CD1-CG 3.48Å; F279-F372 VanDerWaalsContact CD1-CG 3.48Å; F279-F372 HydrophobicContact CD1-CZ 4.21Å; F279-F372 HydrophobicContact CD2-CB 4.22Å; F279-F372 HydrophobicContact CE1-CB 4.01Å; F279-F372 AromaticContact CE1-CD1 3.85Å; F279-F372 HydrophobicContact CE1-CD1 3.85Å; F279-F372 AromaticContact CE1-CD2 3.71Å; F279-F372 HydrophobicContact CE1-CD2 3.71Å; F279-F372 HydrophobicContact CE1-CE1 4.25Å; F279-F372 HydrophobicContact CE1-CE2 4.11Å; F279-F372 AromaticContact CE1-CG 3.55Å; F279-F372 HydrophobicContact CE1-CG 3.55Å; F279-F372 HydrophobicContact CE1-CZ 4.37Å; F279-F372 HydrophobicContact CE2-CB 4.26Å; F279-F372 HydrophobicContact CG-CB 4.09Å; F279-F372 AromaticContact CG-CD2 3.64Å; F279-F372 HydrophobicContact CG-CD2 3.64Å; F279-F372 HydrophobicContact CG-CE2 4.36Å; F279-F372 HydrophobicContact CG-CG 4.02Å; F279-F372 HydrophobicContact CZ-CB 4.14Å; F279-F372 HydrophobicContact CZ-CG 4.18Å; L280-F372 HydrophobicContact CD2-CE2 4.06Å; L280-F372 HydrophobicContact CD2-CZ 4.08Å; L280-F372 HydrophobicContact CG-CE2 4.37Å; V368-F372 PolarHBondContact O-N 2.95Å; F369-F372 PolarHBondContact O-N 2.86Å; G370-F372 PolarHBondContact O-N 3Å; F372-D375 PolarHBondContact O-N 2.87Å; F372-F376 HydrophobicContact CZ-CD2 4.14Å; F372-F376 WeakPolarHBondContact O-CB 3.16Å; F372-F376 PolarHBondContact O-N 3.27Å; F372-F453 AromaticContact CD1-CE1 3.92Å; F372-F453 HydrophobicContact CD1-CE1 3.92Å; F372-F453 HydrophobicContact CD1-CZ 4.09Å; F372-F453 AromaticContact CE1-CE1 3.75Å; F372-F453 HydrophobicContact CE1-CE1 3.75Å; F372-F453 AromaticContact CE1-CZ 3.71Å; F372-F453 HydrophobicContact CE1-CZ 3.71Å; F372-F487 HydrophobicContact CE1-CD1 4.03Å; F372-F487 HydrophobicContact CE1-CD2 4.27Å; F372-F487 AromaticContact CE1-CE1 3.76Å; F372-F487 HydrophobicContact CE1-CE1 3.76Å; F372-F487 HydrophobicContact CE1-CE2 4.06Å; F372-F487 HydrophobicContact CE1-CG 4.28Å; F372-F487 AromaticContact CE1-CZ 3.8Å; F372-F487 HydrophobicContact CE1-CZ 3.8Å; F372-F487 HydrophobicContact CZ-CB 4.32Å; F372-F487 AromaticContact CZ-CD1 3.66Å; F372-F487 HydrophobicContact CZ-CD1 3.66Å; F372-F487 HydrophobicContact CZ-CD2 4.1Å; F372-F487 AromaticContact CZ-CE1 3.89Å; F372-F487 HydrophobicContact CZ-CE1 3.89Å; F372-F487 HydrophobicContact CZ-CE2 4.34Å; F372-F487 AromaticContact CZ-CG 3.78Å; F372-F487 HydrophobicContact CZ-CG 3.78Å; F372-F487 HydrophobicContact CZ-CZ 4.24Å
373Y76Confident73.8Confident83 Ų8350 Ų5033%0.32524%0.236SC..Hα-helixtrans-59-47.4175.7173.7-90.2000111.4F369 G370 K371 F376 Q377 F453F369-Y373 WeakPolarHBondContact O-CB 3.33Å; F369-Y373 PolarHBondContact O-N 3.08Å; G370-Y373 WeakPolarHBondContact O-CB 3.13Å; G370-Y373 PolarHBondContact O-N 3.18Å; K371-Y373 VanDerWaalsContact C-N 3.34Å; Y373-F376 PolarHBondContact O-N 3.48Å; Y373-Q377 WeakPolarHBondContact O-CB 3.48Å; Y373-Q377 PolarHBondContact O-N 3.35Å; Y373-Q377 PolarHBondContact OH-OE1 2.85Å; Y373-F453 AromaticContact CD2-CD1 3.74Å; Y373-F453 HydrophobicContact CD2-CD1 3.74Å; Y373-F453 AromaticContact CD2-CD2 3.94Å; Y373-F453 HydrophobicContact CD2-CD2 3.94Å; Y373-F453 AromaticContact CD2-CE1 3.65Å; Y373-F453 HydrophobicContact CD2-CE1 3.65Å; Y373-F453 AromaticContact CD2-CE2 3.81Å; Y373-F453 HydrophobicContact CD2-CE2 3.81Å; Y373-F453 AromaticContact CD2-CG 3.9Å; Y373-F453 HydrophobicContact CD2-CG 3.9Å; Y373-F453 AromaticContact CD2-CZ 3.68Å; Y373-F453 HydrophobicContact CD2-CZ 3.68Å; Y373-F453 HydrophobicContact CE2-CD1 4.48Å; Y373-F453 HydrophobicContact CE2-CD2 4.09Å; Y373-F453 HydrophobicContact CE2-CE2 4.25Å; Y373-F453 HydrophobicContact CE2-CG 4.2Å; Y373-F453 HydrophobicContact CG-CE1 4.34Å; Y373-F453 HydrophobicContact CG-CZ 4.38Å
374E79.2Confident75.2Confident110 Ų11043.9 Ų43.951%0.51421%0.209SC..Hα-helixtrans-60.5-47.8176.8-74.7173-167.900112.1G370 K371 F376 Q377 K378G370-E374 WeakPolarHBondContact O-CB 3.43Å; G370-E374 WeakPolarHBondContact O-CG 3.32Å; G370-E374 PolarHBondContact O-N 3.2Å; K371-E374 PolarHBondContact O-N 3.09Å; E374-F376 VanDerWaalsContact C-N 3.33Å; E374-F376 PolarHBondContact O-N 3.28Å; E374-Q377 PolarHBondContact O-N 2.84Å; E374-K378 VanDerWaalsContact O-CG 3.28Å; E374-K378 WeakPolarHBondContact O-CG 3.34Å; E374-K378 PolarHBondContact O-N 3.27Å
375D83.7Confident76.7Confident8 Ų844.6 Ų44.64%0.04321%0.214CC..Hα-helixtrans-67-36-179.4-70.9-18.1000111.2Q272 L276 K371 F372 K378Q272-D375 HydrophobicContact CB-CB 4.43Å; Q272-D375 HydrophobicContact CG-CB 4.39Å; Q272-D375 VanDerWaalsContact OE1-CG 3.31Å; Q272-D375 PolarHBondContact OE1-OD1 2.85Å; L276-D375 HydrophobicContact CD2-CB 4.01Å; K371-D375 WeakPolarHBondContact O-CB 3.47Å; K371-D375 PolarHBondContact O-N 3.25Å; F372-D375 PolarHBondContact O-N 2.87Å; D375-K378 IonicContact OD1-NZ 2.78Å; D375-K378 PolarHBondContact OD1-NZ 3.14Å
376F83.1Confident78.1Confident0 Ų044.4 Ų44.40%021%0.213CC..Hα-helixtrans-69.6-43.8175.4-167-91000111.7L276 F372 Y373 E374 K378 V379 Q380 N450 L452 F453 F487 Q490 I491 W494L276-F376 HydrophobicContact CD1-CD2 4.23Å; L276-F376 HydrophobicContact CD2-CB 3.94Å; L276-F376 HydrophobicContact CD2-CD2 4.21Å; F372-F376 HydrophobicContact CZ-CD2 4.14Å; F372-F376 WeakPolarHBondContact O-CB 3.16Å; F372-F376 PolarHBondContact O-N 3.27Å; Y373-F376 PolarHBondContact O-N 3.48Å; E374-F376 VanDerWaalsContact C-N 3.33Å; E374-F376 PolarHBondContact O-N 3.28Å; F376-K378 VanDerWaalsContact C-N 3.34Å; F376-K378 PolarHBondContact O-N 3.4Å; F376-V379 PolarHBondContact O-N 3.34Å; F376-Q380 PolarHBondContact O-N 2.88Å; F376-Q380 VanDerWaalsContact O-N 3.11Å; F376-N450 VanDerWaalsContact CD1-ND2 3.33Å; F376-N450 WeakPolarHBondContact CD1-ND2 3.27Å; F376-N450 WeakPolarHBondContact CE1-ND2 3.13Å; F376-L452 HydrophobicContact CE1-CD1 3.73Å; F376-L452 HydrophobicContact CE2-CD1 4.43Å; F376-L452 HydrophobicContact CZ-CD1 3.34Å; F376-F453 HydrophobicContact CB-CZ 4.18Å; F376-F453 AromaticContact CD1-CE2 3.58Å; F376-F453 HydrophobicContact CD1-CE2 3.58Å; F376-F453 HydrophobicContact CD1-CZ 4.01Å; F376-F453 HydrophobicContact CE1-CE2 4.04Å; F376-F453 HydrophobicContact CG-CE2 4.2Å; F376-F453 HydrophobicContact CG-CZ 4.16Å; F376-F487 HydrophobicContact CD1-CE1 4.48Å; F376-F487 HydrophobicContact CD2-CD1 4.03Å; F376-F487 HydrophobicContact CD2-CE1 4.33Å; F376-F487 HydrophobicContact CE1-CD1 4.37Å; F376-F487 HydrophobicContact CE1-CE1 4.16Å; F376-F487 AromaticContact CE2-CD1 3.52Å; F376-F487 HydrophobicContact CE2-CD1 3.52Å; F376-F487 HydrophobicContact CE2-CE1 4.05Å; F376-F487 AromaticContact CZ-CD1 3.7Å; F376-F487 HydrophobicContact CZ-CD1 3.7Å; F376-F487 AromaticContact CZ-CE1 3.95Å; F376-F487 HydrophobicContact CZ-CE1 3.95Å; F376-Q490 HydrophobicContact CE2-CG 4.33Å; F376-Q490 HydrophobicContact CZ-CB 4.2Å; F376-Q490 HydrophobicContact CZ-CG 3.69Å; F376-I491 HydrophobicContact CE2-CG1 4.21Å; F376-W494 AromaticContact CD1-CH2 3.74Å; F376-W494 HydrophobicContact CD1-CH2 3.74Å; F376-W494 AromaticContact CD2-CH2 3.63Å; F376-W494 HydrophobicContact CD2-CH2 3.63Å; F376-W494 AromaticContact CD2-CZ3 3.62Å; F376-W494 HydrophobicContact CD2-CZ3 3.62Å; F376-W494 AromaticContact CE1-CH2 3.46Å; F376-W494 HydrophobicContact CE1-CH2 3.46Å; F376-W494 VanDerWaalsContact CE1-CH2 3.46Å; F376-W494 HydrophobicContact CE1-CZ2 4.06Å; F376-W494 HydrophobicContact CE1-CZ3 4.36Å; F376-W494 HydrophobicContact CE2-CE3 4.45Å; F376-W494 AromaticContact CE2-CH2 3.3Å; F376-W494 HydrophobicContact CE2-CH2 3.3Å; F376-W494 HydrophobicContact CE2-CZ2 4.35Å; F376-W494 AromaticContact CE2-CZ3 3.35Å; F376-W494 HydrophobicContact CE2-CZ3 3.35Å; F376-W494 AromaticContact CG-CH2 3.83Å; F376-W494 HydrophobicContact CG-CH2 3.83Å; F376-W494 HydrophobicContact CG-CZ3 4.22Å; F376-W494 AromaticContact CZ-CH2 3.22Å; F376-W494 HydrophobicContact CZ-CH2 3.22Å; F376-W494 AromaticContact CZ-CZ2 3.92Å; F376-W494 HydrophobicContact CZ-CZ2 3.92Å; F376-W494 AromaticContact CZ-CZ3 3.78Å; F376-W494 HydrophobicContact CZ-CZ3 3.78Å
377Q82.4Confident79.4Confident57 Ų5742.5 Ų42.527%0.26620%0.202SC..Hα-helixtrans-65.3-37.3-180-170.9179.2-2.400111.2Y373 E374 V379 Q380 D381Y373-Q377 WeakPolarHBondContact O-CB 3.48Å; Y373-Q377 PolarHBondContact O-N 3.35Å; Y373-Q377 PolarHBondContact OH-OE1 2.85Å; E374-Q377 PolarHBondContact O-N 2.84Å; Q377-V379 VanDerWaalsContact C-N 3.27Å; Q377-V379 PolarHBondContact O-N 3.49Å; Q377-Q380 PolarHBondContact O-N 3Å; Q377-Q380 VanDerWaalsContact O-N 3.17Å; Q377-D381 VanDerWaalsContact O-CB 3.3Å; Q377-D381 WeakPolarHBondContact O-CB 3.5Å; Q377-D381 PolarHBondContact O-N 3.48Å
378K87.6Confident80.3Confident89 Ų8941.1 Ų41.139%0.38720%0.195SC..Hα-helixtrans-55.3-42.5174.1-74.6167.7-162.8159.90112.7I268 E374 D375 F376 S382I268-K378 HydrophobicContact CG2-CB 4.08Å; E374-K378 VanDerWaalsContact O-CG 3.28Å; E374-K378 WeakPolarHBondContact O-CG 3.34Å; E374-K378 PolarHBondContact O-N 3.27Å; D375-K378 IonicContact OD1-NZ 2.78Å; D375-K378 PolarHBondContact OD1-NZ 3.14Å; F376-K378 VanDerWaalsContact C-N 3.34Å; F376-K378 PolarHBondContact O-N 3.4Å; K378-S382 PolarHBondContact O-N 3.02Å
379V88.1Confident80.7Confident0 Ų042 Ų420%020%0.197CC..Hα-helixtrans-67.5-47.7177.6-177.90000109.9F265 I268 F269 Q272 L276 F376 Q377 S382 L383 W494F265-V379 HydrophobicContact CE2-CG1 3.89Å; I268-V379 HydrophobicContact CG2-CG2 4.12Å; F269-V379 HydrophobicContact CD2-CG1 3.9Å; F269-V379 HydrophobicContact CD2-CG2 4.43Å; Q272-V379 HydrophobicContact CB-CG2 3.86Å; Q272-V379 HydrophobicContact CG-CG2 4.11Å; L276-V379 HydrophobicContact CD1-CG2 4.4Å; F376-V379 PolarHBondContact O-N 3.34Å; Q377-V379 VanDerWaalsContact C-N 3.27Å; Q377-V379 PolarHBondContact O-N 3.49Å; V379-S382 PolarHBondContact O-N 2.87Å; V379-S382 PolarHBondContact O-OG 2.91Å; V379-L383 PolarHBondContact O-N 3.26Å; V379-W494 HydrophobicContact CB-CE3 4.15Å; V379-W494 HydrophobicContact CB-CH2 3.94Å; V379-W494 HydrophobicContact CB-CZ2 4.35Å; V379-W494 HydrophobicContact CB-CZ3 3.85Å; V379-W494 HydrophobicContact CG1-CD2 3.55Å; V379-W494 HydrophobicContact CG1-CE3 3.53Å; V379-W494 HydrophobicContact CG1-CG 4.08Å; V379-W494 HydrophobicContact CG1-CH2 4.01Å; V379-W494 HydrophobicContact CG1-CZ2 4.07Å; V379-W494 HydrophobicContact CG1-CZ3 3.76Å; V379-W494 HydrophobicContact CG2-CZ3 4.4Å
380Q84.7Confident80.6Confident21 Ų2140.9 Ų40.910%0.09819%0.192CC..Hα-helixtrans-59.1-49.3178-175.467.845.100112.1F376 Q377 S382 L383 D384 W494F376-Q380 PolarHBondContact O-N 2.88Å; F376-Q380 VanDerWaalsContact O-N 3.11Å; Q377-Q380 PolarHBondContact O-N 3Å; Q377-Q380 VanDerWaalsContact O-N 3.17Å; Q380-S382 PolarHBondContact O-N 2.92Å; Q380-L383 PolarHBondContact O-N 3.15Å; Q380-D384 PolarHBondContact NE2-OD1 3.4Å; Q380-D384 PolarHBondContact O-N 2.79Å; Q380-W494 HydrophobicContact CB-CZ2 4.18Å
381D84.4Confident80.3Confident69 Ų6941.7 Ų41.737%0.36919%0.192SC..Hα-helixtrans-57.8-34.8-178.5-74.1-13.4000111.4Q377 D384 E385Q377-D381 VanDerWaalsContact O-CB 3.3Å; Q377-D381 WeakPolarHBondContact O-CB 3.5Å; Q377-D381 PolarHBondContact O-N 3.48Å; D381-D384 PolarHBondContact O-N 3.42Å; D381-E385 PolarHBondContact O-N 3.29Å
382S88.8Confident79.1Confident10 Ų1041.7 Ų41.77%0.0720%0.198CC..Hα-helixtrans-69-29.6177.571.90000113.7F265 K378 V379 Q380F265-S382 WeakPolarHBondContact CD2-OG 3.49Å; K378-S382 PolarHBondContact O-N 3.02Å; V379-S382 PolarHBondContact O-N 2.87Å; V379-S382 PolarHBondContact O-OG 2.91Å; Q380-S382 PolarHBondContact O-N 2.92Å
383L87.6Confident77.5Confident7 Ų745.9 Ų45.94%0.03722%0.22CC..Hα-helixtrans-80.9-36.4170.5-67.5175.7000111.4L166 F257 F265 V379 Q380 E385 V386 M387 W494 I497L166-L383 HydrophobicContact CD1-CD2 4.44Å; F257-L383 HydrophobicContact CE1-CD2 4.15Å; F257-L383 HydrophobicContact CZ-CD2 3.75Å; F265-L383 HydrophobicContact CD2-CD1 4.34Å; F265-L383 HydrophobicContact CD2-CD2 3.52Å; F265-L383 HydrophobicContact CD2-CG 3.68Å; F265-L383 HydrophobicContact CE2-CD1 3.76Å; F265-L383 HydrophobicContact CE2-CD2 3.65Å; F265-L383 HydrophobicContact CE2-CG 3.63Å; F265-L383 HydrophobicContact CG-CD2 4.02Å; F265-L383 HydrophobicContact CZ-CD1 4.41Å; F265-L383 HydrophobicContact CZ-CD2 4.22Å; V379-L383 PolarHBondContact O-N 3.26Å; Q380-L383 PolarHBondContact O-N 3.15Å; L383-E385 PolarHBondContact O-N 3.36Å; L383-V386 WeakPolarHBondContact O-CB 3.35Å; L383-V386 PolarHBondContact O-N 3.47Å; L383-V386 VanDerWaalsContact O-N 3.12Å; L383-M387 PolarHBondContact O-N 3.02Å; L383-W494 VanDerWaalsContact CD1-CD1 3.5Å; L383-I497 HydrophobicContact CD1-CD1 4.42Å
384D82.8Confident76Confident5 Ų543.9 Ų43.93%0.02721%0.214CC..Hα-helixtrans-62.7-33.6176.2-69.9-1.5000111.9Q380 D381 V386 M387 K388 A448Q380-D384 PolarHBondContact NE2-OD1 3.4Å; Q380-D384 PolarHBondContact O-N 2.79Å; D381-D384 PolarHBondContact O-N 3.42Å; D384-V386 VanDerWaalsContact C-N 3.29Å; D384-V386 PolarHBondContact O-N 3.5Å; D384-M387 PolarHBondContact O-N 2.82Å; D384-M387 VanDerWaalsContact OD1-CE 3.29Å; D384-M387 WeakPolarHBondContact OD1-CE 3.41Å; D384-K388 WeakPolarHBondContact O-CB 3.42Å; D384-K388 WeakPolarHBondContact O-CD 3.3Å; D384-K388 WeakPolarHBondContact O-CG 3.4Å; D384-K388 PolarHBondContact O-N 2.97Å; D384-A448 WeakPolarHBondContact OD2-CB 3.44Å
385E84.9Confident74Confident121 Ų12146.4 Ų46.457%0.56523%0.225SC*.Hα-helixtrans-59-40.8173.5-172.2176.2174.300112.1V260 D381 L383 K388V260-E385 HydrophobicContact CG2-CG 4.39Å; D381-E385 PolarHBondContact O-N 3.29Å; L383-E385 PolarHBondContact O-N 3.36Å; E385-K388 PolarHBondContact O-N 2.99Å
386V83.9Confident71.7Confident0 Ų050.1 Ų50.10%025%0.252CS..Hα-helixtrans-63-48.9175.8-178.10000110.4P163 L166 L256 F257 V260 L383 D384 K388 Q389P163-V386 HydrophobicContact CB-CG1 4.14Å; L166-V386 HydrophobicContact CD1-CB 3.85Å; L166-V386 HydrophobicContact CD1-CG1 3.47Å; L166-V386 VanDerWaalsContact CD1-CG1 3.47Å; L166-V386 HydrophobicContact CD1-CG2 4.41Å; L256-V386 WeakPolarHBondContact O-CG1 3.43Å; F257-V386 HydrophobicContact CD1-CG1 4.41Å; F257-V386 HydrophobicContact CD1-CG2 3.52Å; F257-V386 HydrophobicContact CE1-CG2 3.74Å; F257-V386 HydrophobicContact CG-CG1 4.46Å; F257-V386 HydrophobicContact CG-CG2 4.33Å; V260-V386 HydrophobicContact CB-CG2 3.95Å; V260-V386 HydrophobicContact CG1-CG2 3.73Å; V260-V386 HydrophobicContact CG2-CG2 4.31Å; L383-V386 WeakPolarHBondContact O-CB 3.35Å; L383-V386 PolarHBondContact O-N 3.47Å; L383-V386 VanDerWaalsContact O-N 3.12Å; D384-V386 VanDerWaalsContact C-N 3.29Å; D384-V386 PolarHBondContact O-N 3.5Å; V386-K388 VanDerWaalsContact C-N 3.29Å; V386-K388 PolarHBondContact O-N 2.88Å; V386-Q389 WeakPolarHBondContact O-CB 3.38Å; V386-Q389 WeakPolarHBondContact O-CG 3.45Å; V386-Q389 PolarHBondContact O-N 3.29Å
387M83.8Confident69.4Low8 Ų856.3 Ų56.34%0.03929%0.285CS..Hα-helixtrans-65.6-29.3-179-67.2-173.3-74.200113.2P163 L164 L166 E167 L383 D384 Q389 V390P163-M387 WeakPolarHBondContact O-CG 3.39Å; L164-M387 HydrophobicContact CD2-CB 4.34Å; L166-M387 HydrophobicContact CB-CG 4.28Å; L166-M387 HydrophobicContact CB-SD 4.26Å; E167-M387 HydrophobicContact CB-SD 4.07Å; L383-M387 PolarHBondContact O-N 3.02Å; D384-M387 PolarHBondContact O-N 2.82Å; D384-M387 VanDerWaalsContact OD1-CE 3.29Å; D384-M387 WeakPolarHBondContact OD1-CE 3.41Å; M387-Q389 PolarHBondContact O-N 3.33Å; M387-V390 PolarHBondContact O-N 2.95Å
388K79.5Confident67.3Low78 Ų7856.2 Ų56.234%0.33929%0.286SS..Hα-helixtrans-66.6-19.8178.8-78.6164.9-173.7163.50113.8D384 E385 V386 V390 I391 N392D384-K388 WeakPolarHBondContact O-CB 3.42Å; D384-K388 WeakPolarHBondContact O-CD 3.3Å; D384-K388 WeakPolarHBondContact O-CG 3.4Å; D384-K388 PolarHBondContact O-N 2.97Å; E385-K388 PolarHBondContact O-N 2.99Å; V386-K388 VanDerWaalsContact C-N 3.29Å; V386-K388 PolarHBondContact O-N 2.88Å; K388-V390 PolarHBondContact O-N 3.26Å; K388-I391 HydrophobicContact CG-CD1 4.49Å; K388-I391 WeakPolarHBondContact O-CB 3.37Å; K388-I391 PolarHBondContact O-N 2.85Å; K388-N392 PolarHBondContact O-N 3.13Å
389Q71.6Confident64.4Low50 Ų5061 Ų6123%0.23431%0.31CS..THydrogen-bonded Turntrans-57.6-36.8177.9-64.3-169.7-26.700112.7V260 V386 M387 I391V260-Q389 HydrophobicContact CG2-CG 4.2Å; V386-Q389 WeakPolarHBondContact O-CB 3.38Å; V386-Q389 WeakPolarHBondContact O-CG 3.45Å; V386-Q389 PolarHBondContact O-N 3.29Å; M387-Q389 PolarHBondContact O-N 3.33Å; Q389-I391 PolarHBondContact O-N 3.45Å
390V65.4Low61.7Low2 Ų266.8 Ų66.81%0.01235%0.345CS..THydrogen-bonded Turntrans-70.6-22-179.4-170.30000111.8Q160 P163 L164 I203 M387 K388Q160-V390 VanDerWaalsContact O-CG2 3.24Å; Q160-V390 WeakPolarHBondContact O-CG2 3.48Å; P163-V390 HydrophobicContact CB-CG2 3.77Å; P163-V390 HydrophobicContact CG-CG2 3.71Å; L164-V390 HydrophobicContact CD1-CG1 4.06Å; L164-V390 HydrophobicContact CD2-CB 4.28Å; L164-V390 HydrophobicContact CD2-CG2 4.36Å; L164-V390 HydrophobicContact CG-CB 4.27Å; L164-V390 HydrophobicContact CG-CG1 4.26Å; L164-V390 HydrophobicContact CG-CG2 4.13Å; I203-V390 HydrophobicContact CD1-CG1 4.04Å; M387-V390 PolarHBondContact O-N 2.95Å; K388-V390 PolarHBondContact O-N 3.26Å
391I56.7Low59.1Low33 Ų3370.7 Ų70.717%0.16937%0.366CS..THydrogen-bonded Turntrans-86.8-32.9-173.4-47.4-169.9000112.1R199 K388 Q389 L393 E394 Q395 F446R199-I391 VanDerWaalsContact NH2-CG1 3.31Å; K388-I391 HydrophobicContact CG-CD1 4.49Å; K388-I391 WeakPolarHBondContact O-CB 3.37Å; K388-I391 PolarHBondContact O-N 2.85Å; Q389-I391 PolarHBondContact O-N 3.45Å; I391-L393 PolarHBondContact O-N 2.91Å; I391-E394 WeakPolarHBondContact O-CA 3.41Å; I391-E394 WeakPolarHBondContact O-CB 3.38Å; I391-E394 PolarHBondContact O-N 3.22Å; I391-Q395 PolarHBondContact O-N 3.32Å; I391-F446 HydrophobicContact CD1-CD2 3.39Å; I391-F446 HydrophobicContact CD1-CE2 3.33Å; I391-F446 HydrophobicContact CD1-CG 4.42Å; I391-F446 HydrophobicContact CD1-CZ 4.3Å
392N48.3Very low56.4Low118 Ų11872.5 Ų72.563%0.63138%0.375SS*.THydrogen-bonded Turntrans-65.8-18.6176.5-69.8-24.3000112.1K388K388-N392 PolarHBondContact O-N 3.13Å
393L44.8Very low53.5Low94 Ų9474.3 Ų74.349%0.49240%0.395SS..THydrogen-bonded Turntrans-77.6-23.6168.5-72.5151.5000112.8Q160 I391 S396Q160-L393 HydrophobicContact CG-CD1 4.16Å; I391-L393 PolarHBondContact O-N 2.91Å; L393-S396 PolarHBondContact O-OG 3.39Å
394E43.9Very low50.7Low42 Ų4279 Ų7920%0.19642%0.424CS..THydrogen-bonded Turntrans-77.3-30.8-179.8-68.4-174.7132.300112.9R199 I391 S396 N397 I398R199-E394 IonicContact NH2-OE2 2.86Å; R199-E394 PolarHBondContact NH2-OE2 2.94Å; I391-E394 WeakPolarHBondContact O-CA 3.41Å; I391-E394 WeakPolarHBondContact O-CB 3.38Å; I391-E394 PolarHBondContact O-N 3.22Å; E394-S396 PolarHBondContact O-N 3.06Å; E394-N397 PolarHBondContact O-N 2.93Å; E394-I398 HydrophobicContact CB-CD1 3.82Å; E394-I398 HydrophobicContact CB-CG1 4.32Å; E394-I398 HydrophobicContact CG-CD1 3.66Å; E394-I398 PolarHBondContact O-N 3.43Å; E394-I398 VanDerWaalsContact O-N 3.09Å
395Q37Very low48Very low162 Ų16284.3 Ų84.376%0.75746%0.456SS*.THydrogen-bonded Turntrans-66.7-16.9-178.1-85.7-179.3-11.600114.3I391I391-Q395 PolarHBondContact O-N 3.32Å
396S36.3Very low45.3Very low87 Ų8788.1 Ų88.161%0.60847%0.465SS*.THydrogen-bonded Turntrans-89.5-22.3175.856.30000114.2L393 E394L393-S396 PolarHBondContact O-OG 3.39Å; E394-S396 PolarHBondContact O-N 3.06Å
397N35.3Very low42.6Very low130 Ų13093.2 Ų93.270%0.69550%0.501SS*.THydrogen-bonded Turntrans-126-11.3-168-74.3-19000116E394E394-N397 PolarHBondContact O-N 2.93Å
398I37Very low39.8Very low54 Ų5496.9 Ų96.928%0.27753%0.532SS..SBendtrans-103.15.2-173.6-60.1-172.6000114.2E394 V400 L402E394-I398 HydrophobicContact CB-CD1 3.82Å; E394-I398 HydrophobicContact CB-CG1 4.32Å; E394-I398 HydrophobicContact CG-CD1 3.66Å; E394-I398 PolarHBondContact O-N 3.43Å; E394-I398 VanDerWaalsContact O-N 3.09Å; I398-V400 PolarHBondContact O-N 3.49Å; I398-L402 HydrophobicContact CG2-CD1 3.68Å; I398-L402 HydrophobicContact CG2-CG 3.84Å
399E27.1Very low37.3Very low190 Ų190101.8 Ų101.889%0.88856%0.556SS**THydrogen-bonded Turntrans-69.8-16.9173.4-148.3170.7-161.800112.7
400V32.6Very low35.2Very low122 Ų122109.1 Ų109.174%0.73959%0.587SS**THydrogen-bonded Turntrans-93.9-29.8-176.6-179.30000113.7I398I398-V400 PolarHBondContact O-N 3.49Å
401L28.9Very low33.3Very low102 Ų102116.3 Ų116.353%0.53463%0.625SS.*THydrogen-bonded Turntrans-99.3-28.8-168.6-15670.6000114.9G403 V404L401-G403 PolarHBondContact O-N 3.1Å; L401-G403 VanDerWaalsContact O-N 3.14Å; L401-V404 PolarHBondContact O-N 3.18Å; L401-V404 VanDerWaalsContact O-N 3.09Å
402L28.5Very low31.7Very low108 Ų108123.6 Ų123.657%0.56565%0.651SS**THydrogen-bonded Turntrans-67.9-9.3171.2-81.1172.7000113.2I398 V404I398-L402 HydrophobicContact CG2-CD1 3.68Å; I398-L402 HydrophobicContact CG2-CG 3.84Å; L402-V404 VanDerWaalsContact C-N 3.35Å
403G28.7Very low30.8Very low47 Ų47124.9 Ų124.949%0.48566%0.664SS.*THydrogen-bonded Turntrans-73.4-21.5170.200000114L401L401-G403 PolarHBondContact O-N 3.1Å; L401-G403 VanDerWaalsContact O-N 3.14Å
404V27.8Very low30Very low107 Ų107126.4 Ų126.465%0.64867%0.671SS**THydrogen-bonded Turntrans-99.9-29-174.3-177.70000112.6L401 L402 R406L401-V404 PolarHBondContact O-N 3.18Å; L401-V404 VanDerWaalsContact O-N 3.09Å; L402-V404 VanDerWaalsContact C-N 3.35Å; V404-R406 VanDerWaalsContact C-N 3.31Å; V404-R406 PolarHBondContact O-N 2.95Å
405V25.7Very low28.9Very low115 Ų115127.5 Ų127.570%0.69769%0.693SS**G310 helixtrans-81.1-9.2176.6-178.10000112.9S407V405-S407 PolarHBondContact O-N 3.41Å
406R27.8Very low28.5Very low202 Ų202130.3 Ų130.376%0.76270%0.703SS**G310 helixtrans-70.93.1179.5-152.8174.1-67.8168.9-0.4114.4V404V404-R406 VanDerWaalsContact C-N 3.31Å; V404-R406 PolarHBondContact O-N 2.95Å
407S27.1Very low27.8Very low106 Ų106129.5 Ų129.574%0.74171%0.708SS**G310 helixtrans-106.210.8-170.9-52.50000115.5V405V405-S407 PolarHBondContact O-N 3.41Å
408A26.8Very low27.4Very low86 Ų86131.1 Ų131.171%0.71172%0.715SS**SBendtrans-145.827.7-171.300000118.2
409H25.8Very low26.6Very low181 Ų181135.8 Ų135.884%0.83874%0.741SS**  trans-130.364.8165.7-126.2-86.2000112.6
410K28.6Very low26.5Very low204 Ų204130.9 Ų130.989%0.88773%0.728SS**  trans-112.190.4156.5-100.9-173.8177.5178.30107.6
411L25.7Very low26.1Very low153 Ų153132.3 Ų132.380%0.80173%0.729SS**  trans177.5113.9157.3-122.766.3000104.3
412Y22.9Very low25.9Very low185 Ų185133.3 Ų133.373%0.72574%0.739SS**  -160.2104.563.6178.6-98.1000109I414Y412-I414 HydrophobicContact CD1-CG1 4.43Å; Y412-I414 HydrophobicContact CD2-CD1 4.11Å; Y412-I414 HydrophobicContact CD2-CG1 4.1Å; Y412-I414 HydrophobicContact CE1-CB 4Å; Y412-I414 HydrophobicContact CE1-CD1 4.31Å; Y412-I414 HydrophobicContact CE1-CG1 4.02Å; Y412-I414 HydrophobicContact CE2-CB 4.48Å; Y412-I414 HydrophobicContact CE2-CD1 3.28Å; Y412-I414 HydrophobicContact CE2-CG1 3.66Å; Y412-I414 HydrophobicContact CG-CG1 4.48Å; Y412-I414 VanDerWaalsContact CZ-CD1 3.42Å; Y412-I414 WeakPolarHBondContact OH-CD1 3.43Å
413T27.8Very low25.7Very low146 Ų146134.8 Ų134.890%0.89675%0.748SS**  trans-100.5107.116238.30000107.9
414I28.2Very low25.5Very low126 Ų126137.2 Ų137.265%0.64676%0.758SS**  trans-137.3123.1160.9-55.7-166.8000105.4Y412Y412-I414 HydrophobicContact CD1-CG1 4.43Å; Y412-I414 HydrophobicContact CD2-CD1 4.11Å; Y412-I414 HydrophobicContact CD2-CG1 4.1Å; Y412-I414 HydrophobicContact CE1-CB 4Å; Y412-I414 HydrophobicContact CE1-CD1 4.31Å; Y412-I414 HydrophobicContact CE1-CG1 4.02Å; Y412-I414 HydrophobicContact CE2-CB 4.48Å; Y412-I414 HydrophobicContact CE2-CD1 3.28Å; Y412-I414 HydrophobicContact CE2-CG1 3.66Å; Y412-I414 HydrophobicContact CG-CG1 4.48Å; Y412-I414 VanDerWaalsContact CZ-CD1 3.42Å; Y412-I414 WeakPolarHBondContact OH-CD1 3.43Å
415G21.8Very low25.3Very low64 Ų64136.8 Ų136.866%0.6677%0.765SS**  cis166.3131.91.700000108.3
416K27.7Very low25.3Very low222 Ų222138.8 Ų138.897%0.96577%0.772SS**  trans154.3116.8159.5-93.1180-177.9-177.20107.1
417G21.6Very low25Very low69 Ų69135.8 Ų135.871%0.71178%0.776SS**  cis169.8143.60.200000107.5
418I26.5Very low24.8Very low165 Ų165133.6 Ų133.685%0.84677%0.77SS**  trans86.8110.7160.1-47.1175000118
419D21.6Very low25.2Very low152 Ų152139.5 Ų139.581%0.81378%0.783SS**  trans30.7142.5137.1-82.4-15.8000120
420S23.8Very low25Very low87 Ų87134.8 Ų134.861%0.60878%0.776SS**  cis179.91698.155.70000107.8
421I24.6Very low25.3Very low151 Ų151129.7 Ų129.777%0.77477%0.771SS**  trans84.796155-59160.8000117.7
422V24.7Very low25.3Very low123 Ų123127.6 Ų127.675%0.74577%0.765SS**  -5119.8126.6-179.90000114.9
423D24.6Very low25.6Very low139 Ų139129.2 Ų129.274%0.74378%0.775SS**  -171.4158.4100.9-130.5-27.2000113.4
424S25.3Very low25.5Very low99 Ų99124 Ų12469%0.69275%0.751SS**  trans-61.2161.1-177.4-34.10000115
425A22.5Very low25.4Very low97 Ų97124.6 Ų124.680%0.80276%0.763SS**  trans85.2105.9148.800000119.2
426D25.9Very low26Very low157 Ų157128 Ų12884%0.8477%0.765SS**  trans87.1152.3131-137.4-0.9000119.6
427V22.3Very low25.9Very low139 Ų139121.2 Ų121.284%0.84275%0.751SS**  trans89.3108.8174-169.20000116.3
428G21.5Very low26.5Very low61 Ų61124 Ų12463%0.62975%0.748SS**  trans139.483.4135.300000115.3A430G428-A430 PolarHBondContact O-N 3.26Å
429Q36Very low26.5Very low209 Ų209121.9 Ų121.998%0.97774%0.743SS**  trans-50.8107.4147.1-80.2-178.8300108.8
430A21.4Very low27Very low83 Ų83125.5 Ų125.569%0.68675%0.752SS**  trans-150.891.1164.900000109.4G428G428-A430 PolarHBondContact O-N 3.26Å
431A35.4Very low27.1Very low96 Ų96124.8 Ų124.879%0.79376%0.758SS**  trans29.697.5143.600000117.5
432V25.1Very low27.1Very low109 Ų109120.9 Ų120.966%0.66175%0.749SS**  trans-113.892.8148.2-177.70000107.1G434V432-G434 VanDerWaalsContact C-N 3.29Å; V432-G434 PolarHBondContact O-N 3.24Å; V432-G434 VanDerWaalsContact O-N 3.09Å
433K29Very low27.6Very low219 Ų219127.4 Ų127.495%0.95276%0.76SS**  trans-73.789.7163.6-76.7-175.5176.1-178.50107.4
434G26.7Very low27.7Very low38 Ų38125.6 Ų125.639%0.39276%0.764SS.*SBendtrans-170.8153.6171.300000109.7V432 L436V432-G434 VanDerWaalsContact C-N 3.29Å; V432-G434 PolarHBondContact O-N 3.24Å; V432-G434 VanDerWaalsContact O-N 3.09Å; G434-L436 PolarHBondContact O-N 2.97Å
435P26.2Very low27.8Very low137 Ų137123.9 Ų123.989%0.8976%0.762SS**SBendtrans-66.54.9-176.2-16.930.9000115.1
436L34.4Very low28.5Very low136 Ų136123.2 Ų123.271%0.71274%0.741SS**  trans-110.234.4-167.7-135.489.5000114.1G434G434-L436 PolarHBondContact O-N 2.97Å
437A25.3Very low28.8Very low79 Ų79122.7 Ų122.765%0.65374%0.737SS**  trans-102.262.6169.900000110.8
438L34.1Very low29.4Very low127 Ų127117.7 Ų117.767%0.66571%0.71SS**  trans-87.6105.7167.5-83.5165.2000109
439T26.8Very low30.4Very low121 Ų121120.7 Ų120.774%0.74271%0.711SS**  trans-62.3144.2165.742.90000109.7G441T439-G441 PolarHBondContact O-N 3.44Å
440K31Very low31.6Very low229 Ų229111.8 Ų111.8100%0.99667%0.67SS**THydrogen-bonded Turntrans-6329-176.7-72-178.7171.6178.70115.9
441G25.6Very low33.7Very low71 Ų71108.2 Ų108.273%0.73264%0.64SS**THydrogen-bonded Turntrans-122.6-7.8-175.300000116.4T439T439-G441 PolarHBondContact O-N 3.44Å
442A26.3Very low35.3Very low70 Ų70103.8 Ų103.858%0.57960%0.603SS**  trans-108.761.4-172.500000113.1
443R34.7Very low37.3Very low259 Ų259100.1 Ų100.198%0.97758%0.578SS**  trans-104.815.6168.6-83-170.7178.2-178.4-2.6113.7
444A26.2Very low39.1Very low101 Ų10191.6 Ų91.684%0.83554%0.543SS*.SBendtrans-123103.1173.300000108.8
445G27.2Very low40.5Very low63 Ų6390.8 Ų90.865%0.64954%0.535SS*.SBendtrans127.3111.6-178.800000110.9I447G445-I447 VanDerWaalsContact C-N 3.32Å; G445-I447 PolarHBondContact O-N 3.33Å
446F36.9Very low42Very low84 Ų8485.3 Ų85.337%0.36850%0.498SS..  trans-5091.3171.4-88.3-105.5000110.9R199 I391R199-F446 VanDerWaalsContact NH1-CE2 3.26Å; R199-F446 VanDerWaalsContact NH1-CZ 3.26Å; I391-F446 HydrophobicContact CD1-CD2 3.39Å; I391-F446 HydrophobicContact CD1-CE2 3.33Å; I391-F446 HydrophobicContact CD1-CG 4.42Å; I391-F446 HydrophobicContact CD1-CZ 4.3Å
447I32.2Very low42.7Very low145 Ų14583.7 Ų83.774%0.74449%0.49SS*.  trans-91.795.7140.6-57.3178.2000102.8G445 L449G445-I447 VanDerWaalsContact C-N 3.32Å; G445-I447 PolarHBondContact O-N 3.33Å; I447-L449 PolarHBondContact O-N 2.95Å
448A35.6Very low43.5Very low34 Ų3483.2 Ų83.228%0.28148%0.475SS..  trans-59.895.3171.800000107.3D384 N450D384-A448 WeakPolarHBondContact OD2-CB 3.44Å; A448-N450 VanDerWaalsContact C-N 3.32Å; A448-N450 PolarHBondContact O-N 3.42Å
449L41.8Very low43.4Very low125 Ų12583.2 Ų83.265%0.65447%0.47SS*.  trans-60.8106.5160.7-80.3168.4000104.9I447 V451I447-L449 PolarHBondContact O-N 2.95Å; L449-V451 PolarHBondContact O-N 2.82Å
450N61.4Low44.2Very low21 Ų2179.1 Ų79.111%0.11244%0.442CS..  trans-66.4101.4-179.9-165.4-40.1000108.3F376 A448 L452 F453F376-N450 VanDerWaalsContact CD1-ND2 3.33Å; F376-N450 WeakPolarHBondContact CD1-ND2 3.27Å; F376-N450 WeakPolarHBondContact CE1-ND2 3.13Å; A448-N450 VanDerWaalsContact C-N 3.32Å; A448-N450 PolarHBondContact O-N 3.42Å; N450-L452 PolarHBondContact O-N 3.08Å; N450-F453 HydrophobicContact CB-CD2 3.82Å; N450-F453 HydrophobicContact CB-CE2 4.24Å; N450-F453 PolarHBondContact O-N 3.04Å
451V66.6Low44.8Very low9 Ų969.2 Ų69.26%0.05540%0.4CS..G310 helixtrans-53.9-28.9-168.8166.50000112.3V185 F188 Q189 N192 L449 F453 L454V185-V451 HydrophobicContact CB-CG1 4.43Å; V185-V451 HydrophobicContact CG1-CG1 3.82Å; V185-V451 WeakPolarHBondContact O-CG1 3.39Å; F188-V451 HydrophobicContact CB-CB 4.43Å; F188-V451 HydrophobicContact CB-CG1 3.55Å; F188-V451 HydrophobicContact CB-CG2 4Å; Q189-V451 HydrophobicContact CB-CG1 4.39Å; N192-V451 WeakPolarHBondContact ND2-CG2 3.45Å; L449-V451 PolarHBondContact O-N 2.82Å; V451-F453 PolarHBondContact O-N 3.3Å; V451-F453 VanDerWaalsContact O-N 3.15Å; V451-L454 HydrophobicContact CB-CD1 4.49Å; V451-L454 HydrophobicContact CG1-CD1 4.06Å; V451-L454 WeakPolarHBondContact O-CB 3.16Å; V451-L454 WeakPolarHBondContact O-CG 3.41Å; V451-L454 PolarHBondContact O-N 2.96Å
452L68.4Low45.6Very low2 Ų266.7 Ų66.71%0.0137%0.372CS..G310 helixtrans-59.3-24.6176.9-74168.9000114.3F175 V185 F376 N450 R483 L486 F487 Q490F175-L452 HydrophobicContact CE2-CD2 3.71Å; F175-L452 HydrophobicContact CZ-CD2 4.01Å; V185-L452 HydrophobicContact CG1-CD2 4.07Å; F376-L452 HydrophobicContact CE1-CD1 3.73Å; F376-L452 HydrophobicContact CE2-CD1 4.43Å; F376-L452 HydrophobicContact CZ-CD1 3.34Å; N450-L452 PolarHBondContact O-N 3.08Å; L452-R483 PolarHBondContact O-NH1 3.49Å; L452-L486 HydrophobicContact CD2-CB 3.84Å; L452-L486 HydrophobicContact CD2-CD1 4.34Å; L452-F487 HydrophobicContact CB-CD1 4.26Å; L452-F487 HydrophobicContact CB-CE1 3.58Å; L452-F487 HydrophobicContact CB-CZ 3.88Å; L452-F487 HydrophobicContact CD1-CD1 4.06Å; L452-F487 HydrophobicContact CD1-CE1 4.1Å; L452-F487 HydrophobicContact CG-CE1 4.36Å; L452-Q490 HydrophobicContact CD1-CB 3.76Å; L452-Q490 HydrophobicContact CD1-CG 3.75Å
453F66.7Low46.2Very low32 Ų3269.1 Ų69.114%0.1437%0.37CS..G310 helixtrans-90.8-3.6178.7-65.5-88.6000113.8F372 Y373 F376 N450 V451 G455 M456 F487F372-F453 AromaticContact CD1-CE1 3.92Å; F372-F453 HydrophobicContact CD1-CE1 3.92Å; F372-F453 HydrophobicContact CD1-CZ 4.09Å; F372-F453 AromaticContact CE1-CE1 3.75Å; F372-F453 HydrophobicContact CE1-CE1 3.75Å; F372-F453 AromaticContact CE1-CZ 3.71Å; F372-F453 HydrophobicContact CE1-CZ 3.71Å; Y373-F453 AromaticContact CD2-CD1 3.74Å; Y373-F453 HydrophobicContact CD2-CD1 3.74Å; Y373-F453 AromaticContact CD2-CD2 3.94Å; Y373-F453 HydrophobicContact CD2-CD2 3.94Å; Y373-F453 AromaticContact CD2-CE1 3.65Å; Y373-F453 HydrophobicContact CD2-CE1 3.65Å; Y373-F453 AromaticContact CD2-CE2 3.81Å; Y373-F453 HydrophobicContact CD2-CE2 3.81Å; Y373-F453 AromaticContact CD2-CG 3.9Å; Y373-F453 HydrophobicContact CD2-CG 3.9Å; Y373-F453 AromaticContact CD2-CZ 3.68Å; Y373-F453 HydrophobicContact CD2-CZ 3.68Å; Y373-F453 HydrophobicContact CE2-CD1 4.48Å; Y373-F453 HydrophobicContact CE2-CD2 4.09Å; Y373-F453 HydrophobicContact CE2-CE2 4.25Å; Y373-F453 HydrophobicContact CE2-CG 4.2Å; Y373-F453 HydrophobicContact CG-CE1 4.34Å; Y373-F453 HydrophobicContact CG-CZ 4.38Å; F376-F453 HydrophobicContact CB-CZ 4.18Å; F376-F453 AromaticContact CD1-CE2 3.58Å; F376-F453 HydrophobicContact CD1-CE2 3.58Å; F376-F453 HydrophobicContact CD1-CZ 4.01Å; F376-F453 HydrophobicContact CE1-CE2 4.04Å; F376-F453 HydrophobicContact CG-CE2 4.2Å; F376-F453 HydrophobicContact CG-CZ 4.16Å; N450-F453 HydrophobicContact CB-CD2 3.82Å; N450-F453 HydrophobicContact CB-CE2 4.24Å; N450-F453 PolarHBondContact O-N 3.04Å; V451-F453 PolarHBondContact O-N 3.3Å; V451-F453 VanDerWaalsContact O-N 3.15Å; F453-G455 PolarHBondContact O-N 3.06Å; F453-M456 HydrophobicContact CB-CE 4.46Å; F453-M456 HydrophobicContact CD1-CE 3.3Å; F453-M456 HydrophobicContact CE1-CE 3.74Å; F453-M456 HydrophobicContact CG-CE 4.11Å; F453-M456 WeakPolarHBondContact O-CB 3.4Å; F453-M456 PolarHBondContact O-N 3.44Å; F453-F487 HydrophobicContact CD1-CZ 4.02Å; F453-F487 HydrophobicContact CD2-CE1 4.33Å; F453-F487 HydrophobicContact CD2-CZ 4.31Å; F453-F487 HydrophobicContact CE1-CE1 4.11Å; F453-F487 AromaticContact CE1-CZ 3.72Å; F453-F487 HydrophobicContact CE1-CZ 3.72Å; F453-F487 AromaticContact CE2-CE1 3.78Å; F453-F487 HydrophobicContact CE2-CE1 3.78Å; F453-F487 HydrophobicContact CE2-CZ 4.07Å; F453-F487 HydrophobicContact CG-CZ 4.3Å; F453-F487 AromaticContact CZ-CE1 3.64Å; F453-F487 HydrophobicContact CZ-CE1 3.64Å; F453-F487 AromaticContact CZ-CZ 3.76Å; F453-F487 HydrophobicContact CZ-CZ 3.76Å
454L67Low46.7Very low40 Ų4059.1 Ų59.121%0.20933%0.334CS..THydrogen-bonded Turntrans-59.2128.5177.1-69.9177.9000111.4E184 F188 V451 M456 R483E184-L454 HydrophobicContact CG-CB 4.35Å; E184-L454 HydrophobicContact CG-CD1 4.37Å; F188-L454 HydrophobicContact CB-CD1 3.61Å; F188-L454 HydrophobicContact CD1-CD1 4.01Å; F188-L454 HydrophobicContact CD2-CD1 3.26Å; F188-L454 HydrophobicContact CE2-CD1 3.84Å; F188-L454 HydrophobicContact CG-CD1 3.35Å; F188-L454 HydrophobicContact CZ-CD1 4.43Å; V451-L454 HydrophobicContact CB-CD1 4.49Å; V451-L454 HydrophobicContact CG1-CD1 4.06Å; V451-L454 WeakPolarHBondContact O-CB 3.16Å; V451-L454 WeakPolarHBondContact O-CG 3.41Å; V451-L454 PolarHBondContact O-N 2.96Å; L454-M456 VanDerWaalsContact C-N 3.27Å; L454-M456 PolarHBondContact O-N 2.82Å; L454-R483 PolarHBondContact O-NH1 3.48Å; L454-R483 PolarHBondContact O-NH2 3.08Å
455G56Low47.5Very low22 Ų2254.8 Ų54.823%0.22730%0.298CS..THydrogen-bonded Turntrans76.87.1-175.800000114.8R71 F453R71-G455 WeakPolarHBondContact CD-O 3.31Å; R71-G455 PolarHBondContact NH1-O 2.66Å; F453-G455 PolarHBondContact O-N 3.06Å
456M57.4Low48.2Very low22 Ų2253.8 Ų53.811%0.10828%0.277CS..  trans-105.567.6171.3-60.3-148.7-53.500111.8F453 L454 I458 F479 R483 F487F453-M456 HydrophobicContact CB-CE 4.46Å; F453-M456 HydrophobicContact CD1-CE 3.3Å; F453-M456 HydrophobicContact CE1-CE 3.74Å; F453-M456 HydrophobicContact CG-CE 4.11Å; F453-M456 WeakPolarHBondContact O-CB 3.4Å; F453-M456 PolarHBondContact O-N 3.44Å; L454-M456 VanDerWaalsContact C-N 3.27Å; L454-M456 PolarHBondContact O-N 2.82Å; M456-I458 PolarHBondContact O-N 3.34Å; M456-F479 HydrophobicContact CG-CZ 4.26Å; M456-R483 HydrophobicContact SD-CB 4.32Å; M456-R483 HydrophobicContact SD-CG 4.04Å; M456-F487 HydrophobicContact CE-CE2 3.38Å; M456-F487 HydrophobicContact CE-CZ 3.41Å; M456-F487 VanDerWaalsContact CE-CZ 3.41Å; M456-F487 HydrophobicContact SD-CE2 4.01Å
457D50.2Low48.4Very low102 Ų10253.5 Ų53.555%0.54528%0.283SS..  trans-69.8123.2170.9-81.9-29000110.7F459 F460 I461D457-F459 PolarHBondContact O-N 3.01Å; D457-F460 HydrophobicContact CB-CB 3.55Å; D457-F460 CarbonylContact O-C 3.59Å; D457-F460 WeakPolarHBondContact O-CA 3.39Å; D457-F460 VanDerWaalsContact O-CB 3.24Å; D457-F460 WeakPolarHBondContact O-CB 3.31Å; D457-F460 PolarHBondContact O-N 2.97Å; D457-I461 PolarHBondContact O-N 3.48Å
458I40.6Very low48.9Very low68 Ų6847.9 Ų47.935%0.34925%0.254SS..Hα-helixtrans-55.4-41.1177.2-67.5171000111.3N366 M456 F460N366-I458 HydrophobicContact CB-CG2 3.55Å; N366-I458 WeakPolarHBondContact OD1-CG2 3.23Å; N366-I458 PolarHBondContact OD1-O 3.3Å; M456-I458 PolarHBondContact O-N 3.34Å; I458-F460 PolarHBondContact O-N 2.87Å
459F33.6Very low49.2Very low127 Ų12746.8 Ų46.856%0.55725%0.245SC*.Hα-helixtrans-64.2-28.7175.9-176.1-104.1000112.8D457 K463D457-F459 PolarHBondContact O-N 3.01Å; F459-K463 HydrophobicContact CE1-CD 3.86Å; F459-K463 HydrophobicContact CZ-CD 4.14Å; F459-K463 VanDerWaalsContact O-CB 3.23Å; F459-K463 WeakPolarHBondContact O-CB 3.35Å; F459-K463 PolarHBondContact O-N 2.92Å
460F43.6Very low49.2Very low36 Ų3647.4 Ų47.416%0.15824%0.242CC..Hα-helixtrans-85.5-40.9-177-171.8-89.1000111.7R71 D457 I458 A462 K463 E464R71-F460 HydrophobicContact CB-CZ 4.09Å; R71-F460 VanDerWaalsContact CD-CE1 3.4Å; R71-F460 HydrophobicContact CG-CE1 3.87Å; R71-F460 HydrophobicContact CG-CE2 4.37Å; R71-F460 HydrophobicContact CG-CZ 3.51Å; D457-F460 HydrophobicContact CB-CB 3.55Å; D457-F460 CarbonylContact O-C 3.59Å; D457-F460 WeakPolarHBondContact O-CA 3.39Å; D457-F460 VanDerWaalsContact O-CB 3.24Å; D457-F460 WeakPolarHBondContact O-CB 3.31Å; D457-F460 PolarHBondContact O-N 2.97Å; I458-F460 PolarHBondContact O-N 2.87Å; F460-A462 PolarHBondContact O-N 3.1Å; F460-K463 PolarHBondContact O-N 3.09Å; F460-E464 HydrophobicContact CD1-CB 3.9Å; F460-E464 HydrophobicContact CD1-CG 3.84Å; F460-E464 HydrophobicContact CD2-CB 4.46Å; F460-E464 HydrophobicContact CD2-CG 3.55Å; F460-E464 HydrophobicContact CE1-CB 3.88Å; F460-E464 HydrophobicContact CE1-CG 3.7Å; F460-E464 WeakPolarHBondContact CE1-OE2 3.03Å; F460-E464 HydrophobicContact CE2-CB 4.48Å; F460-E464 HydrophobicContact CE2-CG 3.44Å; F460-E464 VanDerWaalsContact CE2-CG 3.44Å; F460-E464 WeakPolarHBondContact CE2-OE1 3.37Å; F460-E464 WeakPolarHBondContact CE2-OE2 3.35Å; F460-E464 HydrophobicContact CG-CB 4.22Å; F460-E464 HydrophobicContact CG-CG 3.79Å; F460-E464 HydrophobicContact CZ-CB 4.24Å; F460-E464 HydrophobicContact CZ-CG 3.55Å; F460-E464 WeakPolarHBondContact CZ-OE1 3.35Å; F460-E464 WeakPolarHBondContact CZ-OE2 3.29Å; F460-E464 WeakPolarHBondContact O-CA 3.28Å; F460-E464 WeakPolarHBondContact O-CB 3.25Å; F460-E464 PolarHBondContact O-N 3.31Å
461I43.1Very low48.4Very low20 Ų2049.3 Ų49.310%0.10327%0.267CS..Hα-helixtrans-53.1-44.2175-66.9172.6000110.6L321 F369 D457 S465L321-I461 HydrophobicContact CD1-CG2 3.68Å; L321-I461 WeakPolarHBondContact CD1-O 3.35Å; L321-I461 HydrophobicContact CD2-CG2 3.76Å; L321-I461 HydrophobicContact CG-CG2 4.3Å; F369-I461 HydrophobicContact CD1-CD1 3.98Å; F369-I461 HydrophobicContact CD2-CD1 4.43Å; F369-I461 HydrophobicContact CD2-CG2 4.44Å; F369-I461 HydrophobicContact CE1-CD1 3.71Å; F369-I461 HydrophobicContact CE2-CD1 4.22Å; F369-I461 HydrophobicContact CE2-CG2 3.8Å; F369-I461 HydrophobicContact CG-CD1 4.33Å; F369-I461 HydrophobicContact CZ-CD1 3.86Å; F369-I461 HydrophobicContact CZ-CG2 4.09Å; D457-I461 PolarHBondContact O-N 3.48Å; I461-S465 WeakPolarHBondContact O-CB 3.15Å; I461-S465 PolarHBondContact O-N 3.28Å; I461-S465 PolarHBondContact O-OG 3.49Å
462A41.6Very low48Very low19 Ų1950.7 Ų50.716%0.15728%0.277CS..Hα-helixtrans-77.3-36.6179.700000114.5Q362 F460 S465Q362-A462 HydrophobicContact CB-CB 4Å; Q362-A462 HydrophobicContact CG-CB 3.53Å; F460-A462 PolarHBondContact O-N 3.1Å; A462-S465 PolarHBondContact O-OG 3.35Å
463K40.1Very low47.4Very low121 Ų12151.4 Ų51.453%0.52628%0.28SS..Hα-helixtrans-83.9-38.1-176.8-171.6178.2179.4-176.90112.7F459 F460F459-K463 HydrophobicContact CE1-CD 3.86Å; F459-K463 HydrophobicContact CZ-CD 4.14Å; F459-K463 VanDerWaalsContact O-CB 3.23Å; F459-K463 WeakPolarHBondContact O-CB 3.35Å; F459-K463 PolarHBondContact O-N 2.92Å; F460-K463 PolarHBondContact O-N 3.09Å
464E44.4Very low47.2Very low49 Ų4951.6 Ų51.623%0.22928%0.284CS..Hα-helixtrans-85.3-30.3-178.4-78.3-135.7165.700114.3F460 L466 T467 L468F460-E464 HydrophobicContact CD1-CB 3.9Å; F460-E464 HydrophobicContact CD1-CG 3.84Å; F460-E464 HydrophobicContact CD2-CB 4.46Å; F460-E464 HydrophobicContact CD2-CG 3.55Å; F460-E464 HydrophobicContact CE1-CB 3.88Å; F460-E464 HydrophobicContact CE1-CG 3.7Å; F460-E464 WeakPolarHBondContact CE1-OE2 3.03Å; F460-E464 HydrophobicContact CE2-CB 4.48Å; F460-E464 HydrophobicContact CE2-CG 3.44Å; F460-E464 VanDerWaalsContact CE2-CG 3.44Å; F460-E464 WeakPolarHBondContact CE2-OE1 3.37Å; F460-E464 WeakPolarHBondContact CE2-OE2 3.35Å; F460-E464 HydrophobicContact CG-CB 4.22Å; F460-E464 HydrophobicContact CG-CG 3.79Å; F460-E464 HydrophobicContact CZ-CB 4.24Å; F460-E464 HydrophobicContact CZ-CG 3.55Å; F460-E464 WeakPolarHBondContact CZ-OE1 3.35Å; F460-E464 WeakPolarHBondContact CZ-OE2 3.29Å; F460-E464 WeakPolarHBondContact O-CA 3.28Å; F460-E464 WeakPolarHBondContact O-CB 3.25Å; F460-E464 PolarHBondContact O-N 3.31Å; E464-L466 PolarHBondContact O-N 3.48Å; E464-T467 WeakPolarHBondContact CA-OG1 3.33Å; E464-T467 CarbonylContact O-C 3.56Å; E464-T467 PolarHBondContact O-N 2.82Å; E464-T467 PolarHBondContact O-OG1 3.43Å; E464-T467 VanDerWaalsContact O-OG1 3.06Å; E464-L468 HydrophobicContact CB-CD1 4.46Å; E464-L468 VanDerWaalsContact O-CB 3.28Å; E464-L468 WeakPolarHBondContact O-CB 3.48Å; E464-L468 PolarHBondContact O-N 3.09Å; E464-L468 WeakPolarHBondContact OE2-CD1 3.31Å
465S43.4Very low47.1Very low10 Ų1052.8 Ų52.87%0.0729%0.287CS..Hα-helixtrans-51.8-43.4168.752.90000111.5V317 L321 I461 A462 T467 A469V317-S465 WeakPolarHBondContact CG1-O 3.49Å; L321-S465 WeakPolarHBondContact CD1-OG 3.28Å; I461-S465 WeakPolarHBondContact O-CB 3.15Å; I461-S465 PolarHBondContact O-N 3.28Å; I461-S465 PolarHBondContact O-OG 3.49Å; A462-S465 PolarHBondContact O-OG 3.35Å; S465-T467 VanDerWaalsContact C-N 3.32Å; S465-T467 PolarHBondContact O-N 3Å; S465-A469 WeakPolarHBondContact O-CB 3.46Å; S465-A469 PolarHBondContact O-N 3.45Å
466L41.2Very low47.5Very low42 Ų4252.5 Ų52.522%0.2228%0.281CS..Hα-helixtrans-62.4-32.6176.6-166.473.3000113.8V357 E464 K470V357-L466 HydrophobicContact CB-CD2 4.2Å; V357-L466 HydrophobicContact CG1-CD1 4.4Å; V357-L466 HydrophobicContact CG1-CD2 4.19Å; V357-L466 HydrophobicContact CG2-CD1 3.72Å; V357-L466 HydrophobicContact CG2-CD2 3.89Å; V357-L466 HydrophobicContact CG2-CG 4.47Å; E464-L466 PolarHBondContact O-N 3.48Å; L466-K470 WeakPolarHBondContact O-CD 3.4Å; L466-K470 WeakPolarHBondContact O-CG 3.49Å
467T41.3Very low47.9Very low78 Ų7851.5 Ų51.548%0.47928%0.276SS..Hα-helixtrans-90-41.5178.658.80000112.4E464 S465 K470 G471E464-T467 WeakPolarHBondContact CA-OG1 3.33Å; E464-T467 CarbonylContact O-C 3.56Å; E464-T467 PolarHBondContact O-N 2.82Å; E464-T467 PolarHBondContact O-OG1 3.43Å; E464-T467 VanDerWaalsContact O-OG1 3.06Å; S465-T467 VanDerWaalsContact C-N 3.32Å; S465-T467 PolarHBondContact O-N 3Å; T467-K470 WeakPolarHBondContact O-CB 3.41Å; T467-K470 PolarHBondContact O-N 2.95Å; T467-G471 PolarHBondContact O-N 2.94Å
468L42.7Very low49.2Very low26 Ų2652.6 Ų52.614%0.13628%0.276CS..Hα-helixtrans-65.1-36.5174.9-108.471.3000112.1T68 E464 K470 G471 S472 V476T68-L468 HydrophobicContact CG2-CD1 4.39Å; E464-L468 HydrophobicContact CB-CD1 4.46Å; E464-L468 VanDerWaalsContact O-CB 3.28Å; E464-L468 WeakPolarHBondContact O-CB 3.48Å; E464-L468 PolarHBondContact O-N 3.09Å; E464-L468 WeakPolarHBondContact OE2-CD1 3.31Å; L468-K470 PolarHBondContact O-N 3.14Å; L468-G471 CarbonylContact O-C 3.57Å; L468-G471 WeakPolarHBondContact O-CA 3.37Å; L468-G471 PolarHBondContact O-N 2.74Å; L468-S472 CarbonylContact O-C 3.53Å; L468-S472 PolarHBondContact O-N 3.29Å; L468-V476 HydrophobicContact CB-CG2 3.5Å; L468-V476 HydrophobicContact CD2-CG2 3.47Å; L468-V476 VanDerWaalsContact CD2-CG2 3.47Å; L468-V476 HydrophobicContact CG-CG2 4.06Å
469A41.3Very low50.8Low11 Ų1150 Ų509%0.09126%0.262CS..Hα-helixtrans-70.6-23.1175.800000114.5V317 S465V317-A469 HydrophobicContact CB-CB 3.43Å; V317-A469 VanDerWaalsContact CB-CB 3.43Å; V317-A469 HydrophobicContact CG1-CB 3.17Å; V317-A469 HydrophobicContact CG2-CB 3.11Å; S465-A469 WeakPolarHBondContact O-CB 3.46Å; S465-A469 PolarHBondContact O-N 3.45Å
470K43.1Very low52.7Low139 Ų13944.8 Ų44.860%0.60424%0.24SC*.Hα-helixtrans-73.1-19.8168.1-69.5175.2179.9-178.60111.6L314 L466 T467 L468L314-K470 VanDerWaalsContact CD2-CE 3.48Å; L466-K470 WeakPolarHBondContact O-CD 3.4Å; L466-K470 WeakPolarHBondContact O-CG 3.49Å; T467-K470 WeakPolarHBondContact O-CB 3.41Å; T467-K470 PolarHBondContact O-N 2.95Å; L468-K470 PolarHBondContact O-N 3.14Å
471G45.4Very low54.5Low61 Ų6146 Ų4663%0.62924%0.244SC*.Hα-helixtrans-106-51.4-176.300000116.5T467 L468T467-G471 PolarHBondContact O-N 2.94Å; L468-G471 CarbonylContact O-C 3.57Å; L468-G471 WeakPolarHBondContact O-CA 3.37Å; L468-G471 PolarHBondContact O-N 2.74Å
472S56.2Low56.4Low38 Ų3845.2 Ų45.227%0.26624%0.24SC..  trans-16397.8178.1-176.40000113.4L468 T474 K475L468-S472 CarbonylContact O-C 3.53Å; L468-S472 PolarHBondContact O-N 3.29Å; S472-T474 PolarHBondContact O-N 3.06Å; S472-T474 VanDerWaalsContact O-N 3.1Å; S472-K475 PolarHBondContact O-N 2.94Å; S472-K475 VanDerWaalsContact O-N 3.08Å
473K56.3Low58.2Low16 Ų1644.9 Ų44.97%0.0724%0.235CC..Hα-helixtrans-53.7-29.3175.9-65.1173.4-176.4170.90113.9M293 N294 K475 S477M293-K473 HydrophobicContact CB-CD 4.41Å; N294-K473 HydrophobicContact CB-CB 4.1Å; K473-K475 VanDerWaalsContact C-N 3.35Å; K473-K475 PolarHBondContact O-N 3.25Å; K473-S477 PolarHBondContact O-N 3.31Å
474T63.3Low60.2Low37 Ų3739.1 Ų39.123%0.22721%0.21CC..Hα-helixtrans-64.8-36.2179-32.30000112.5N294 S472 K478N294-T474 PolarHBondContact ND2-OG1 3Å; S472-T474 PolarHBondContact O-N 3.06Å; S472-T474 VanDerWaalsContact O-N 3.1Å; T474-K478 WeakPolarHBondContact O-CG 3.46Å; T474-K478 PolarHBondContact O-N 3.15Å
475K64.6Low62.4Low65 Ų6539.3 Ų39.328%0.28322%0.22SC..Hα-helixtrans-71.7-43.3-176.4-67.4-176.4177.2-168.70112.1D66 T68 S472 K473 S477 K478 F479D66-K475 IonicContact OD1-NZ 3.91Å; D66-K475 PolarHBondContact OD1-NZ 3.45Å; D66-K475 WeakPolarHBondContact OD2-CE 3.2Å; D66-K475 IonicContact OD2-NZ 2.77Å; D66-K475 PolarHBondContact OD2-NZ 3.06Å; T68-K475 HydrophobicContact CG2-CD 4.12Å; S472-K475 PolarHBondContact O-N 2.94Å; S472-K475 VanDerWaalsContact O-N 3.08Å; K473-K475 VanDerWaalsContact C-N 3.35Å; K473-K475 PolarHBondContact O-N 3.25Å; K475-S477 VanDerWaalsContact C-N 3.33Å; K475-S477 PolarHBondContact O-N 2.78Å; K475-K478 PolarHBondContact O-N 2.79Å; K475-F479 PolarHBondContact O-N 3.4Å
476V63.8Low64.4Low16 Ų1639.2 Ų39.210%0.09722%0.218CC..Hα-helixtrans-59.2-47.4174.4-178.40000110.4L290 L468 K478 F479 L480L290-V476 HydrophobicContact CD1-CB 4.27Å; L290-V476 HydrophobicContact CD1-CG1 3.85Å; L468-V476 HydrophobicContact CB-CG2 3.5Å; L468-V476 HydrophobicContact CD2-CG2 3.47Å; L468-V476 VanDerWaalsContact CD2-CG2 3.47Å; L468-V476 HydrophobicContact CG-CG2 4.06Å; V476-K478 PolarHBondContact O-N 2.78Å; V476-F479 PolarHBondContact O-N 3.09Å; V476-L480 HydrophobicContact CG1-CD1 3.96Å; V476-L480 HydrophobicContact CG1-CG 4.25Å; V476-L480 WeakPolarHBondContact O-CG 3.42Å; V476-L480 PolarHBondContact O-N 2.82Å
477S65.8Low66.5Low1 Ų137.5 Ų37.51%0.00721%0.209CC..Hα-helixtrans-58.5-47.8178.2174.10000111.9A287 K473 K475 F479 L480 R481A287-S477 WeakPolarHBondContact O-CB 3.42Å; A287-S477 PolarHBondContact O-OG 2.96Å; K473-S477 PolarHBondContact O-N 3.31Å; K475-S477 VanDerWaalsContact C-N 3.33Å; K475-S477 PolarHBondContact O-N 2.78Å; S477-F479 PolarHBondContact O-N 3.22Å; S477-L480 PolarHBondContact O-N 3.41Å; S477-R481 WeakPolarHBondContact O-CG 3.46Å; S477-R481 PolarHBondContact O-N 2.97Å; S477-R481 PolarHBondContact OG-NH1 2.92Å
478K77.4Confident68.9Low125 Ų12536.1 Ų36.154%0.54320%0.195SC..Hα-helixtrans-59.1-44.7175.7-75-176.7176-166.40112.7T474 K475 V476 R481 A482T474-K478 WeakPolarHBondContact O-CG 3.46Å; T474-K478 PolarHBondContact O-N 3.15Å; K475-K478 PolarHBondContact O-N 2.79Å; V476-K478 PolarHBondContact O-N 2.78Å; K478-R481 PolarHBondContact O-N 3.27Å; K478-A482 VanDerWaalsContact O-CB 3.32Å; K478-A482 WeakPolarHBondContact O-CB 3.47Å; K478-A482 PolarHBondContact O-N 3.07Å
479F74.4Confident71.3Confident14 Ų1435.2 Ų35.26%0.06119%0.191CC..Hα-helixtrans-62.3-47.2177.4175.1-95.8000112.5R71 H181 M456 K475 V476 S477 R481 A482 R483R71-F479 VanDerWaalsContact CZ-CE2 3.5Å; R71-F479 VanDerWaalsContact NH1-CE1 3.34Å; R71-F479 VanDerWaalsContact NH2-CE2 3.26Å; H181-F479 HydrophobicContact CB-CD2 3.97Å; M456-F479 HydrophobicContact CG-CZ 4.26Å; K475-F479 PolarHBondContact O-N 3.4Å; V476-F479 PolarHBondContact O-N 3.09Å; S477-F479 PolarHBondContact O-N 3.22Å; F479-R481 VanDerWaalsContact C-N 3.34Å; F479-R481 PolarHBondContact O-N 3.45Å; F479-A482 WeakPolarHBondContact O-CB 3.4Å; F479-A482 PolarHBondContact O-N 3.34Å; F479-R483 HydrophobicContact CD1-CG 4.46Å; F479-R483 HydrophobicContact CD2-CG 4.46Å; F479-R483 HydrophobicContact CE1-CG 3.82Å; F479-R483 HydrophobicContact CE2-CG 3.82Å; F479-R483 HydrophobicContact CZ-CG 3.42Å; F479-R483 VanDerWaalsContact CZ-CG 3.42Å; F479-R483 PolarHBondContact O-N 3.42Å
480L73.4Confident73.6Confident16 Ų1635.2 Ų35.28%0.08419%0.189CC..Hα-helixtrans-61.1-43.1179.8-72.4178.1000111.5V283 A287 L290 V476 S477 R483 A484V283-L480 HydrophobicContact CG1-CB 3.89Å; V283-L480 HydrophobicContact CG1-CD2 4.16Å; V283-L480 HydrophobicContact CG1-CG 4.46Å; A287-L480 HydrophobicContact CB-CB 4.16Å; L290-L480 HydrophobicContact CD1-CD1 4.28Å; V476-L480 HydrophobicContact CG1-CD1 3.96Å; V476-L480 HydrophobicContact CG1-CG 4.25Å; V476-L480 WeakPolarHBondContact O-CG 3.42Å; V476-L480 PolarHBondContact O-N 2.82Å; S477-L480 PolarHBondContact O-N 3.41Å; L480-R483 PolarHBondContact O-N 3.1Å; L480-A484 VanDerWaalsContact O-CB 3.32Å; L480-A484 WeakPolarHBondContact O-CB 3.27Å; L480-A484 PolarHBondContact O-N 3.48Å
481R81.6Confident75.9Confident62 Ų6228.6 Ų28.623%0.23416%0.16CC..Hα-helixtrans-63.2-44.2174.2-68.2-168.5175.7121.6-15112.4E284 A287 E291 S477 K478 F479 R483 A484 A485E284-R481 VanDerWaalsContact OE1-CD 3.25Å; E284-R481 WeakPolarHBondContact OE1-CD 3.38Å; E284-R481 WeakPolarHBondContact OE1-CG 3.49Å; E284-R481 IonicContact OE1-CZ 2.58Å; E284-R481 IonicContact OE1-NE 3.75Å; E284-R481 PolarHBondContact OE1-NE 3.44Å; E284-R481 WeakPolarHBondContact OE2-CG 3.24Å; A287-R481 HydrophobicContact CB-CG 3.64Å; E291-R481 IonicContact OE2-CZ 2.6Å; E291-R481 IonicContact OE2-NH1 3.18Å; E291-R481 PolarHBondContact OE2-NH1 3.13Å; E291-R481 IonicContact OE2-NH2 2.9Å; E291-R481 PolarHBondContact OE2-NH2 3Å; S477-R481 WeakPolarHBondContact O-CG 3.46Å; S477-R481 PolarHBondContact O-N 2.97Å; S477-R481 PolarHBondContact OG-NH1 2.92Å; K478-R481 PolarHBondContact O-N 3.27Å; F479-R481 VanDerWaalsContact C-N 3.34Å; F479-R481 PolarHBondContact O-N 3.45Å; R481-R483 VanDerWaalsContact C-N 3.28Å; R481-R483 PolarHBondContact O-N 3.19Å; R481-A484 PolarHBondContact O-N 3.39Å; R481-A485 WeakPolarHBondContact O-CB 3.21Å; R481-A485 PolarHBondContact O-N 3.12Å
482A83.4Confident78.2Confident4 Ų430 Ų303%0.03315%0.15CC..Hα-helixtrans-59.1-40.8178.600000111.7N179 H181 N182 K478 F479 L486N179-A482 WeakPolarHBondContact ND2-CB 3.36Å; H181-A482 HydrophobicContact CB-CB 3.88Å; N182-A482 PolarHBondContact ND2-O 3.23Å; K478-A482 VanDerWaalsContact O-CB 3.32Å; K478-A482 WeakPolarHBondContact O-CB 3.47Å; K478-A482 PolarHBondContact O-N 3.07Å; F479-A482 WeakPolarHBondContact O-CB 3.4Å; F479-A482 PolarHBondContact O-N 3.34Å; A482-L486 PolarHBondContact O-N 2.85Å
483R79.9Confident80Confident11 Ų1128.2 Ų28.24%0.04214%0.138CC..Hα-helixtrans-73.7-42.6175.8-69.6-67.5168.7142.23.6112.9H181 N182 V185 L452 L454 M456 F479 L480 R481 A485 L486 F487H181-R483 PolarHBondContact O-NH2 2.9Å; N182-R483 PolarHBondContact OD1-NE 3.47Å; V185-R483 VanDerWaalsContact CG2-CZ 3.46Å; L452-R483 PolarHBondContact O-NH1 3.49Å; L454-R483 PolarHBondContact O-NH1 3.48Å; L454-R483 PolarHBondContact O-NH2 3.08Å; M456-R483 HydrophobicContact SD-CB 4.32Å; M456-R483 HydrophobicContact SD-CG 4.04Å; F479-R483 HydrophobicContact CD1-CG 4.46Å; F479-R483 HydrophobicContact CD2-CG 4.46Å; F479-R483 HydrophobicContact CE1-CG 3.82Å; F479-R483 HydrophobicContact CE2-CG 3.82Å; F479-R483 HydrophobicContact CZ-CG 3.42Å; F479-R483 VanDerWaalsContact CZ-CG 3.42Å; F479-R483 PolarHBondContact O-N 3.42Å; L480-R483 PolarHBondContact O-N 3.1Å; R481-R483 VanDerWaalsContact C-N 3.28Å; R481-R483 PolarHBondContact O-N 3.19Å; R483-A485 VanDerWaalsContact C-N 3.25Å; R483-A485 PolarHBondContact O-N 3.34Å; R483-L486 PolarHBondContact O-N 2.87Å; R483-F487 WeakPolarHBondContact O-CD2 3.37Å; R483-F487 PolarHBondContact O-N 3.3Å
484A81.6Confident81.8Confident1 Ų127.6 Ų27.61%0.00814%0.135CC..Hα-helixtrans-59.5-40.1176.400000111.4L280 V283 L480 R481 F487 R488L280-A484 HydrophobicContact CD2-CB 4.42Å; V283-A484 HydrophobicContact CG1-CB 4.14Å; L480-A484 VanDerWaalsContact O-CB 3.32Å; L480-A484 WeakPolarHBondContact O-CB 3.27Å; L480-A484 PolarHBondContact O-N 3.48Å; R481-A484 PolarHBondContact O-N 3.39Å; A484-F487 PolarHBondContact O-N 2.97Å; A484-R488 WeakPolarHBondContact O-CB 3.4Å; A484-R488 WeakPolarHBondContact O-CG 3.49Å; A484-R488 PolarHBondContact O-N 3.25Å
485A89.5Confident83.4Confident52 Ų5229.1 Ų29.143%0.4314%0.14SC..Hα-helixtrans-61.5-45.5174.500000112.5R481 R483 R488 S489R481-A485 WeakPolarHBondContact O-CB 3.21Å; R481-A485 PolarHBondContact O-N 3.12Å; R483-A485 VanDerWaalsContact C-N 3.25Å; R483-A485 PolarHBondContact O-N 3.34Å; A485-R488 PolarHBondContact O-N 2.68Å; A485-S489 PolarHBondContact O-N 3.14Å
486L86.3Confident84.8Confident8 Ų831.2 Ų31.24%0.04215%0.149CC..Hα-helixtrans-60.3-47175.4-80.8175.8000112.7F175 N182 V185 L186 L452 A482 R483 R488 S489 Q490F175-L486 HydrophobicContact CD2-CD2 3.87Å; F175-L486 HydrophobicContact CE1-CD2 4.39Å; F175-L486 HydrophobicContact CE2-CD2 3.66Å; F175-L486 HydrophobicContact CG-CD2 4.38Å; F175-L486 HydrophobicContact CZ-CD2 3.91Å; N182-L486 HydrophobicContact CB-CD1 3.71Å; N182-L486 HydrophobicContact CB-CG 4.41Å; N182-L486 VanDerWaalsContact ND2-CD1 3.3Å; N182-L486 WeakPolarHBondContact ND2-CD1 3.28Å; N182-L486 VanDerWaalsContact ND2-CG 3.34Å; N182-L486 WeakPolarHBondContact ND2-CG 3.37Å; N182-L486 WeakPolarHBondContact OD1-CD1 3.03Å; V185-L486 HydrophobicContact CB-CD1 4.16Å; V185-L486 HydrophobicContact CG1-CD1 3.94Å; V185-L486 HydrophobicContact CG2-CD1 4.27Å; L186-L486 HydrophobicContact CD2-CD2 4.34Å; L452-L486 HydrophobicContact CD2-CB 3.84Å; L452-L486 HydrophobicContact CD2-CD1 4.34Å; A482-L486 PolarHBondContact O-N 2.85Å; R483-L486 PolarHBondContact O-N 2.87Å; L486-R488 VanDerWaalsContact C-N 3.34Å; L486-R488 PolarHBondContact O-N 3.31Å; L486-S489 PolarHBondContact O-N 3.4Å; L486-Q490 PolarHBondContact O-N 3.26Å
487F86.1Confident86.3Confident6 Ų630.7 Ų30.73%0.02615%0.146CC..Hα-helixtrans-64.9-38.4178.6-78-66.2000112L280 F372 F376 L452 F453 M456 R483 A484 Q490 I491L280-F487 HydrophobicContact CD1-CB 3.61Å; L280-F487 HydrophobicContact CD2-CB 3.72Å; L280-F487 HydrophobicContact CD2-CD2 4.3Å; L280-F487 HydrophobicContact CD2-CG 4.28Å; L280-F487 HydrophobicContact CG-CB 4.32Å; F372-F487 HydrophobicContact CE1-CD1 4.03Å; F372-F487 HydrophobicContact CE1-CD2 4.27Å; F372-F487 AromaticContact CE1-CE1 3.76Å; F372-F487 HydrophobicContact CE1-CE1 3.76Å; F372-F487 HydrophobicContact CE1-CE2 4.06Å; F372-F487 HydrophobicContact CE1-CG 4.28Å; F372-F487 AromaticContact CE1-CZ 3.8Å; F372-F487 HydrophobicContact CE1-CZ 3.8Å; F372-F487 HydrophobicContact CZ-CB 4.32Å; F372-F487 AromaticContact CZ-CD1 3.66Å; F372-F487 HydrophobicContact CZ-CD1 3.66Å; F372-F487 HydrophobicContact CZ-CD2 4.1Å; F372-F487 AromaticContact CZ-CE1 3.89Å; F372-F487 HydrophobicContact CZ-CE1 3.89Å; F372-F487 HydrophobicContact CZ-CE2 4.34Å; F372-F487 AromaticContact CZ-CG 3.78Å; F372-F487 HydrophobicContact CZ-CG 3.78Å; F372-F487 HydrophobicContact CZ-CZ 4.24Å; F376-F487 HydrophobicContact CD1-CE1 4.48Å; F376-F487 HydrophobicContact CD2-CD1 4.03Å; F376-F487 HydrophobicContact CD2-CE1 4.33Å; F376-F487 HydrophobicContact CE1-CD1 4.37Å; F376-F487 HydrophobicContact CE1-CE1 4.16Å; F376-F487 AromaticContact CE2-CD1 3.52Å; F376-F487 HydrophobicContact CE2-CD1 3.52Å; F376-F487 HydrophobicContact CE2-CE1 4.05Å; F376-F487 AromaticContact CZ-CD1 3.7Å; F376-F487 HydrophobicContact CZ-CD1 3.7Å; F376-F487 AromaticContact CZ-CE1 3.95Å; F376-F487 HydrophobicContact CZ-CE1 3.95Å; L452-F487 HydrophobicContact CB-CD1 4.26Å; L452-F487 HydrophobicContact CB-CE1 3.58Å; L452-F487 HydrophobicContact CB-CZ 3.88Å; L452-F487 HydrophobicContact CD1-CD1 4.06Å; L452-F487 HydrophobicContact CD1-CE1 4.1Å; L452-F487 HydrophobicContact CG-CE1 4.36Å; F453-F487 HydrophobicContact CD1-CZ 4.02Å; F453-F487 HydrophobicContact CD2-CE1 4.33Å; F453-F487 HydrophobicContact CD2-CZ 4.31Å; F453-F487 HydrophobicContact CE1-CE1 4.11Å; F453-F487 AromaticContact CE1-CZ 3.72Å; F453-F487 HydrophobicContact CE1-CZ 3.72Å; F453-F487 AromaticContact CE2-CE1 3.78Å; F453-F487 HydrophobicContact CE2-CE1 3.78Å; F453-F487 HydrophobicContact CE2-CZ 4.07Å; F453-F487 HydrophobicContact CG-CZ 4.3Å; F453-F487 AromaticContact CZ-CE1 3.64Å; F453-F487 HydrophobicContact CZ-CE1 3.64Å; F453-F487 AromaticContact CZ-CZ 3.76Å; F453-F487 HydrophobicContact CZ-CZ 3.76Å; M456-F487 HydrophobicContact CE-CE2 3.38Å; M456-F487 HydrophobicContact CE-CZ 3.41Å; M456-F487 VanDerWaalsContact CE-CZ 3.41Å; M456-F487 HydrophobicContact SD-CE2 4.01Å; R483-F487 WeakPolarHBondContact O-CD2 3.37Å; R483-F487 PolarHBondContact O-N 3.3Å; A484-F487 PolarHBondContact O-N 2.97Å; F487-Q490 PolarHBondContact O-N 2.89Å; F487-I491 VanDerWaalsContact O-CG1 3.27Å; F487-I491 WeakPolarHBondContact O-CG1 3.43Å; F487-I491 PolarHBondContact O-N 2.92Å
488R91.8Very high87.7Confident50 Ų5030.6 Ų30.619%0.18915%0.145CC..Hα-helixtrans-61.3-48.7173.8-77-171-177.6107-0111.1L280 D281 E284 A484 A485 L486 Q490 I491 E492L280-R488 VanDerWaalsContact C-NH2 3.34Å; L280-R488 HydrophobicContact CB-CG 4.36Å; L280-R488 HydrophobicContact CD1-CB 4.41Å; L280-R488 HydrophobicContact CD1-CG 3.59Å; L280-R488 PolarHBondContact O-NH2 3Å; L280-R488 VanDerWaalsContact O-NH2 3.12Å; D281-R488 IonicContact OD1-CZ 2.84Å; D281-R488 IonicContact OD1-NE 2.98Å; D281-R488 IonicContact OD1-NH2 2.83Å; D281-R488 PolarHBondContact OD1-NH2 3.45Å; E284-R488 IonicContact OE2-NH1 3.26Å; A484-R488 WeakPolarHBondContact O-CB 3.4Å; A484-R488 WeakPolarHBondContact O-CG 3.49Å; A484-R488 PolarHBondContact O-N 3.25Å; A485-R488 PolarHBondContact O-N 2.68Å; L486-R488 VanDerWaalsContact C-N 3.34Å; L486-R488 PolarHBondContact O-N 3.31Å; R488-Q490 VanDerWaalsContact C-N 3.27Å; R488-Q490 PolarHBondContact O-N 3.24Å; R488-I491 PolarHBondContact O-N 3.47Å; R488-I491 VanDerWaalsContact O-N 3.1Å; R488-E492 WeakPolarHBondContact O-CB 3.28Å; R488-E492 VanDerWaalsContact O-CG 3.3Å; R488-E492 WeakPolarHBondContact O-CG 3.36Å; R488-E492 PolarHBondContact O-N 3.21Å
489S91.9Very high88.5Confident6 Ų628.1 Ų28.14%0.04214%0.138CC..Hα-helixtrans-56.2-39.6176.1170.20000112.6T174 A485 L486 S493T174-S489 PolarHBondContact OG1-OG 2.9Å; A485-S489 PolarHBondContact O-N 3.14Å; L486-S489 PolarHBondContact O-N 3.4Å; S489-S493 PolarHBondContact O-N 3.45Å; S489-S493 PolarHBondContact O-OG 2.9Å
490Q90.1Very high89.4Confident11 Ų1128.1 Ų28.15%0.05114%0.139CC..Hα-helixtrans-67.7-44.3174.7-175.958.733.200112.8F376 L452 L486 F487 R488 E492 S493 W494F376-Q490 HydrophobicContact CE2-CG 4.33Å; F376-Q490 HydrophobicContact CZ-CB 4.2Å; F376-Q490 HydrophobicContact CZ-CG 3.69Å; L452-Q490 HydrophobicContact CD1-CB 3.76Å; L452-Q490 HydrophobicContact CD1-CG 3.75Å; L486-Q490 PolarHBondContact O-N 3.26Å; F487-Q490 PolarHBondContact O-N 2.89Å; R488-Q490 VanDerWaalsContact C-N 3.27Å; R488-Q490 PolarHBondContact O-N 3.24Å; Q490-E492 VanDerWaalsContact C-N 3.34Å; Q490-S493 WeakPolarHBondContact O-CB 3.09Å; Q490-S493 PolarHBondContact O-N 3.36Å; Q490-W494 HydrophobicContact CG-CD2 4.26Å; Q490-W494 HydrophobicContact CG-CH2 4.22Å; Q490-W494 HydrophobicContact CG-CZ2 3.86Å; Q490-W494 VanDerWaalsContact NE2-CE2 3.28Å; Q490-W494 PolarHBondContact O-N 3.27Å
491I91.5Very high90.3Very high0 Ų027.8 Ų27.80%014%0.138CC..Hα-helixtrans-64.9-39.7178.5-67.4163.6000111F269 Q273 L276 L277 L280 F376 F487 R488 S493 W494 E495F269-I491 HydrophobicContact CE2-CG2 4.23Å; F269-I491 HydrophobicContact CZ-CG2 4.29Å; Q273-I491 HydrophobicContact CG-CG2 4.08Å; L276-I491 HydrophobicContact CB-CD1 3.67Å; L276-I491 HydrophobicContact CD1-CD1 4.32Å; L276-I491 HydrophobicContact CD1-CG1 4.41Å; L277-I491 HydrophobicContact CD2-CD1 4.28Å; L277-I491 HydrophobicContact CD2-CG2 3.94Å; L277-I491 HydrophobicContact CG-CG2 4.26Å; L280-I491 HydrophobicContact CD1-CD1 3.62Å; F376-I491 HydrophobicContact CE2-CG1 4.21Å; F487-I491 VanDerWaalsContact O-CG1 3.27Å; F487-I491 WeakPolarHBondContact O-CG1 3.43Å; F487-I491 PolarHBondContact O-N 2.92Å; R488-I491 PolarHBondContact O-N 3.47Å; R488-I491 VanDerWaalsContact O-N 3.1Å; I491-S493 VanDerWaalsContact C-N 3.28Å; I491-S493 PolarHBondContact O-N 3.48Å; I491-W494 HydrophobicContact CB-CE3 4.48Å; I491-W494 HydrophobicContact CG1-CE3 4.04Å; I491-W494 HydrophobicContact CG1-CZ3 4.1Å; I491-W494 PolarHBondContact O-N 2.62Å; I491-E495 WeakPolarHBondContact O-CB 3.03Å; I491-E495 PolarHBondContact O-N 2.91Å
492E94.1Very high90.7Very high90 Ų9028.1 Ų28.142%0.42115%0.149SC..Hα-helixtrans-62.6-35.9174.1-73.6169.3-170.300111.4R488 Q490 E495 K496R488-E492 WeakPolarHBondContact O-CB 3.28Å; R488-E492 VanDerWaalsContact O-CG 3.3Å; R488-E492 WeakPolarHBondContact O-CG 3.36Å; R488-E492 PolarHBondContact O-N 3.21Å; Q490-E492 VanDerWaalsContact C-N 3.34Å; E492-E495 WeakPolarHBondContact O-CB 3.39Å; E492-E495 PolarHBondContact O-N 2.89Å; E492-K496 WeakPolarHBondContact O-CG 3.46Å; E492-K496 PolarHBondContact O-N 2.97Å
493S93.3Very high91Very high2 Ų233.6 Ų33.61%0.01417%0.174CC..Hα-helixtrans-66.5-42.9174-590000111.7D171 S489 Q490 I491 E495 K496 I497D171-S493 PolarHBondContact N-OG 3.2Å; S489-S493 PolarHBondContact O-N 3.45Å; S489-S493 PolarHBondContact O-OG 2.9Å; Q490-S493 WeakPolarHBondContact O-CB 3.09Å; Q490-S493 PolarHBondContact O-N 3.36Å; I491-S493 VanDerWaalsContact C-N 3.28Å; I491-S493 PolarHBondContact O-N 3.48Å; S493-E495 VanDerWaalsContact C-N 3.31Å; S493-E495 PolarHBondContact O-N 3.32Å; S493-K496 WeakPolarHBondContact O-CB 3.33Å; S493-K496 PolarHBondContact O-N 3.4Å; S493-I497 WeakPolarHBondContact O-CG1 3.12Å; S493-I497 PolarHBondContact O-N 2.6Å; S493-I497 VanDerWaalsContact O-N 3.13Å
494W94.3Very high91Very high2 Ų234.2 Ų34.21%0.00818%0.18CC..Hα-helixtrans-63.8-36.1172.6-66.4-30.3000112.9F265 F269 L276 F376 V379 Q380 L383 Q490 I491 I497 C498F265-W494 HydrophobicContact CZ-CB 4.17Å; F269-W494 HydrophobicContact CD2-CB 3.81Å; F269-W494 HydrophobicContact CD2-CE3 4.43Å; F269-W494 HydrophobicContact CE2-CB 3.41Å; F269-W494 VanDerWaalsContact CE2-CB 3.41Å; F269-W494 HydrophobicContact CE2-CE3 4.14Å; F269-W494 HydrophobicContact CE2-CG 4.39Å; F269-W494 HydrophobicContact CZ-CB 4.03Å; L276-W494 HydrophobicContact CD1-CZ3 4.28Å; F376-W494 AromaticContact CD1-CH2 3.74Å; F376-W494 HydrophobicContact CD1-CH2 3.74Å; F376-W494 AromaticContact CD2-CH2 3.63Å; F376-W494 HydrophobicContact CD2-CH2 3.63Å; F376-W494 AromaticContact CD2-CZ3 3.62Å; F376-W494 HydrophobicContact CD2-CZ3 3.62Å; F376-W494 AromaticContact CE1-CH2 3.46Å; F376-W494 HydrophobicContact CE1-CH2 3.46Å; F376-W494 VanDerWaalsContact CE1-CH2 3.46Å; F376-W494 HydrophobicContact CE1-CZ2 4.06Å; F376-W494 HydrophobicContact CE1-CZ3 4.36Å; F376-W494 HydrophobicContact CE2-CE3 4.45Å; F376-W494 AromaticContact CE2-CH2 3.3Å; F376-W494 HydrophobicContact CE2-CH2 3.3Å; F376-W494 HydrophobicContact CE2-CZ2 4.35Å; F376-W494 AromaticContact CE2-CZ3 3.35Å; F376-W494 HydrophobicContact CE2-CZ3 3.35Å; F376-W494 AromaticContact CG-CH2 3.83Å; F376-W494 HydrophobicContact CG-CH2 3.83Å; F376-W494 HydrophobicContact CG-CZ3 4.22Å; F376-W494 AromaticContact CZ-CH2 3.22Å; F376-W494 HydrophobicContact CZ-CH2 3.22Å; F376-W494 AromaticContact CZ-CZ2 3.92Å; F376-W494 HydrophobicContact CZ-CZ2 3.92Å; F376-W494 AromaticContact CZ-CZ3 3.78Å; F376-W494 HydrophobicContact CZ-CZ3 3.78Å; V379-W494 HydrophobicContact CB-CE3 4.15Å; V379-W494 HydrophobicContact CB-CH2 3.94Å; V379-W494 HydrophobicContact CB-CZ2 4.35Å; V379-W494 HydrophobicContact CB-CZ3 3.85Å; V379-W494 HydrophobicContact CG1-CD2 3.55Å; V379-W494 HydrophobicContact CG1-CE3 3.53Å; V379-W494 HydrophobicContact CG1-CG 4.08Å; V379-W494 HydrophobicContact CG1-CH2 4.01Å; V379-W494 HydrophobicContact CG1-CZ2 4.07Å; V379-W494 HydrophobicContact CG1-CZ3 3.76Å; V379-W494 HydrophobicContact CG2-CZ3 4.4Å; Q380-W494 HydrophobicContact CB-CZ2 4.18Å; L383-W494 VanDerWaalsContact CD1-CD1 3.5Å; Q490-W494 HydrophobicContact CG-CD2 4.26Å; Q490-W494 HydrophobicContact CG-CH2 4.22Å; Q490-W494 HydrophobicContact CG-CZ2 3.86Å; Q490-W494 VanDerWaalsContact NE2-CE2 3.28Å; Q490-W494 PolarHBondContact O-N 3.27Å; I491-W494 HydrophobicContact CB-CE3 4.48Å; I491-W494 HydrophobicContact CG1-CE3 4.04Å; I491-W494 HydrophobicContact CG1-CZ3 4.1Å; I491-W494 PolarHBondContact O-N 2.62Å; W494-I497 PolarHBondContact O-N 3.47Å; W494-C498 WeakPolarHBondContact O-CB 3.1Å; W494-C498 PolarHBondContact O-N 3.41Å
495E95.8Very high90.3Very high70 Ų7043.4 Ų43.433%0.32722%0.22SC..Hα-helixtrans-63.4-41.9174.6-177.5166.7-148.700111.6F269 Q273 I491 E492 S493 I497 C498 N499F269-E495 HydrophobicContact CE1-CB 4Å; F269-E495 HydrophobicContact CE1-CG 4.45Å; F269-E495 HydrophobicContact CZ-CB 3.77Å; Q273-E495 PolarHBondContact NE2-OE1 3.01Å; Q273-E495 VanDerWaalsContact NE2-OE1 3.14Å; Q273-E495 PolarHBondContact NE2-OE2 2.75Å; I491-E495 WeakPolarHBondContact O-CB 3.03Å; I491-E495 PolarHBondContact O-N 2.91Å; E492-E495 WeakPolarHBondContact O-CB 3.39Å; E492-E495 PolarHBondContact O-N 2.89Å; S493-E495 VanDerWaalsContact C-N 3.31Å; S493-E495 PolarHBondContact O-N 3.32Å; E495-I497 PolarHBondContact O-N 2.86Å; E495-C498 PolarHBondContact O-N 3.04Å; E495-N499 VanDerWaalsContact O-CB 3.31Å; E495-N499 WeakPolarHBondContact O-CB 3.13Å; E495-N499 PolarHBondContact O-N 2.81Å; E495-N499 PolarHBondContact O-ND2 3.43Å
496K95.4Very high89Confident108 Ų10844 Ų4447%0.4722%0.215SC..Hα-helixtrans-59.1-46.2173.4-71.8174.7-175.1179.60111.6D171 E492 S493 N499 S500D171-K496 IonicContact OD2-NZ 3.8Å; D171-K496 PolarHBondContact OD2-NZ 2.67Å; E492-K496 WeakPolarHBondContact O-CG 3.46Å; E492-K496 PolarHBondContact O-N 2.97Å; S493-K496 WeakPolarHBondContact O-CB 3.33Å; S493-K496 PolarHBondContact O-N 3.4Å; K496-N499 PolarHBondContact O-N 3.05Å; K496-S500 WeakPolarHBondContact O-CB 3.24Å; K496-S500 PolarHBondContact O-N 2.86Å
497I94.4Very high87.9Confident5 Ų547.4 Ų47.43%0.02624%0.236CC..Hα-helixtrans-59.2-51.6174.8-63168.8000109.6K169 M253 F257 F265 L383 S493 W494 E495 N499 S500 L501K169-I497 HydrophobicContact CB-CD1 3.91Å; K169-I497 HydrophobicContact CB-CG1 4.18Å; M253-I497 HydrophobicContact CE-CG1 4.31Å; M253-I497 HydrophobicContact CG-CG2 4.31Å; M253-I497 HydrophobicContact SD-CB 4.46Å; M253-I497 HydrophobicContact SD-CG1 4.12Å; M253-I497 HydrophobicContact SD-CG2 4.07Å; F257-I497 HydrophobicContact CE2-CG2 4.23Å; F257-I497 HydrophobicContact CZ-CG2 4.24Å; F265-I497 HydrophobicContact CD1-CG2 4.39Å; F265-I497 HydrophobicContact CE1-CB 4.18Å; F265-I497 HydrophobicContact CE1-CG2 3.69Å; F265-I497 HydrophobicContact CZ-CB 4.31Å; F265-I497 HydrophobicContact CZ-CG2 4.12Å; L383-I497 HydrophobicContact CD1-CD1 4.42Å; S493-I497 WeakPolarHBondContact O-CG1 3.12Å; S493-I497 PolarHBondContact O-N 2.6Å; S493-I497 VanDerWaalsContact O-N 3.13Å; W494-I497 PolarHBondContact O-N 3.47Å; E495-I497 PolarHBondContact O-N 2.86Å; I497-N499 VanDerWaalsContact C-N 3.34Å; I497-N499 PolarHBondContact O-N 3.44Å; I497-S500 WeakPolarHBondContact O-CB 3.39Å; I497-S500 PolarHBondContact O-N 2.69Å; I497-L501 HydrophobicContact CG2-CD1 3.75Å; I497-L501 HydrophobicContact CG2-CG 4.26Å; I497-L501 VanDerWaalsContact O-CG 3.23Å; I497-L501 WeakPolarHBondContact O-CG 3.38Å; I497-L501 PolarHBondContact O-N 3.2Å
498C94.8Very high86.8Confident0 Ų050.2 Ų50.20%025%0.249CC..Hα-helixtrans-60-41.5-178.1-169.40000112.8F265 F269 H270 W494 E495 L501 C502F265-C498 HydrophobicContact CE1-CB 3.93Å; F269-C498 HydrophobicContact CD1-CB 3.61Å; F269-C498 HydrophobicContact CE1-CB 3.98Å; F269-C498 HydrophobicContact CG-CB 4.41Å; H270-C498 PolarHBondContact NE2-SG 2.98Å; H270-C498 VanDerWaalsContact NE2-SG 3.39Å; W494-C498 WeakPolarHBondContact O-CB 3.1Å; W494-C498 PolarHBondContact O-N 3.41Å; E495-C498 PolarHBondContact O-N 3.04Å; C498-L501 PolarHBondContact O-N 2.74Å; C498-C502 WeakPolarHBondContact O-CB 3.13Å; C498-C502 PolarHBondContact O-N 3.36Å; C498-C502 PolarHBondContact O-SG 3.29Å
499N95.2Very high85.6Confident73 Ų7353.4 Ų53.439%0.3927%0.265SS..Hα-helixtrans-65.2-42.7177.5-75.5-26.8000111.4E495 K496 I497 C502 Q503E495-N499 VanDerWaalsContact O-CB 3.31Å; E495-N499 WeakPolarHBondContact O-CB 3.13Å; E495-N499 PolarHBondContact O-N 2.81Å; E495-N499 PolarHBondContact O-ND2 3.43Å; K496-N499 PolarHBondContact O-N 3.05Å; I497-N499 VanDerWaalsContact C-N 3.34Å; I497-N499 PolarHBondContact O-N 3.44Å; N499-C502 PolarHBondContact O-N 3.32Å; N499-Q503 WeakPolarHBondContact O-CB 3.49Å; N499-Q503 VanDerWaalsContact O-CG 3.27Å; N499-Q503 WeakPolarHBondContact O-CG 3.34Å; N499-Q503 PolarHBondContact O-N 3.21Å
500S93.5Very high84.5Confident13 Ų1357.6 Ų57.69%0.09129%0.285CS..Hα-helixtrans-62.6-45.5177.3-173.90000111.4D250 M253 K496 I497 C502 Q503 S504D250-S500 WeakPolarHBondContact CA-OG 3.32Å; D250-S500 WeakPolarHBondContact CB-O 3.45Å; D250-S500 WeakPolarHBondContact OD1-CA 3.33Å; D250-S500 VanDerWaalsContact OD1-CB 3.31Å; D250-S500 WeakPolarHBondContact OD1-CB 3.37Å; D250-S500 PolarHBondContact OD1-OG 3.35Å; M253-S500 WeakPolarHBondContact CB-OG 3.06Å; K496-S500 WeakPolarHBondContact O-CB 3.24Å; K496-S500 PolarHBondContact O-N 2.86Å; I497-S500 WeakPolarHBondContact O-CB 3.39Å; I497-S500 PolarHBondContact O-N 2.69Å; S500-C502 VanDerWaalsContact C-N 3.34Å; S500-C502 PolarHBondContact O-N 3.16Å; S500-Q503 PolarHBondContact O-N 2.94Å; S500-Q503 VanDerWaalsContact O-N 3.09Å; S500-S504 PolarHBondContact O-N 3.33Å
501L91.9Very high83.3Confident9 Ų957.1 Ų57.15%0.04728%0.282CS..Hα-helixtrans-62.5-38.2174.4-60.2167.5000112.5M253 E254 F257 F265 I266 I497 C498 Q503M253-L501 HydrophobicContact CG-CD2 4Å; M253-L501 HydrophobicContact CG-CG 4.28Å; E254-L501 HydrophobicContact CB-CD2 4.16Å; E254-L501 VanDerWaalsContact OE2-CD2 3.25Å; E254-L501 WeakPolarHBondContact OE2-CD2 3.4Å; F257-L501 HydrophobicContact CD2-CD1 4.47Å; F257-L501 HydrophobicContact CD2-CD2 3.8Å; F257-L501 HydrophobicContact CE1-CD1 4.41Å; F257-L501 HydrophobicContact CE2-CD1 3.68Å; F257-L501 HydrophobicContact CE2-CD2 3.67Å; F257-L501 HydrophobicContact CE2-CG 4.22Å; F257-L501 HydrophobicContact CZ-CD1 3.64Å; F257-L501 HydrophobicContact CZ-CD2 4.45Å; F265-L501 HydrophobicContact CD1-CD1 3.62Å; F265-L501 HydrophobicContact CE1-CD1 3.98Å; I266-L501 HydrophobicContact CD1-CB 3.82Å; I266-L501 HydrophobicContact CG1-CB 4.21Å; I266-L501 HydrophobicContact CG1-CD1 4.2Å; I497-L501 HydrophobicContact CG2-CD1 3.75Å; I497-L501 HydrophobicContact CG2-CG 4.26Å; I497-L501 VanDerWaalsContact O-CG 3.23Å; I497-L501 WeakPolarHBondContact O-CG 3.38Å; I497-L501 PolarHBondContact O-N 3.2Å; C498-L501 PolarHBondContact O-N 2.74Å; L501-Q503 VanDerWaalsContact C-N 3.3Å; L501-Q503 PolarHBondContact O-N 3.28Å
502C90.6Very high82.2Confident70 Ų7060.9 Ų60.947%0.47330%0.299SS..Hα-helixtrans-68.2-28.1174.7-69.90000113.3C498 N499 S500C498-C502 WeakPolarHBondContact O-CB 3.13Å; C498-C502 PolarHBondContact O-N 3.36Å; C498-C502 PolarHBondContact O-SG 3.29Å; N499-C502 PolarHBondContact O-N 3.32Å; S500-C502 VanDerWaalsContact C-N 3.34Å; S500-C502 PolarHBondContact O-N 3.16Å
503Q88.3Confident81.3Confident119 Ų11960.6 Ų60.656%0.55630%0.3SS*.Hα-helixtrans-86.8-19-178.3-74.7178.529.800113.2D250 N499 S500 L501 K505D250-Q503 WeakPolarHBondContact OD2-CB 3.48Å; N499-Q503 WeakPolarHBondContact O-CB 3.49Å; N499-Q503 VanDerWaalsContact O-CG 3.27Å; N499-Q503 WeakPolarHBondContact O-CG 3.34Å; N499-Q503 PolarHBondContact O-N 3.21Å; S500-Q503 PolarHBondContact O-N 2.94Å; S500-Q503 VanDerWaalsContact O-N 3.09Å; L501-Q503 VanDerWaalsContact C-N 3.3Å; L501-Q503 PolarHBondContact O-N 3.28Å; Q503-K505 WeakPolarHBondContact O-CG 3.21Å; Q503-K505 PolarHBondContact O-N 3.32Å
504S81.8Confident80.4Confident23 Ų2362 Ų6216%0.16131%0.307CS..  trans-52.9111.2173.6-1760000110.6S500S500-S504 PolarHBondContact O-N 3.33Å
505K64.9Low79.6Confident195 Ų19562.6 Ų62.685%0.84831%0.31SS*.  trans-82.2-14.9-169.6-67.3-178.4-177.2164.60114.3Q503Q503-K505 WeakPolarHBondContact O-CG 3.21Å; Q503-K505 PolarHBondContact O-N 3.32Å
506L62.8Low78.6Confident64 Ų6464.3 Ų64.334%0.33532%0.318SS..SBendtrans-118.4133.7-173.8-73.9165.9000108E510 N511L506-E510 HydrophobicContact CD2-CB 4.49Å; L506-N511 VanDerWaalsContact CB-CG 3.5Å; L506-N511 WeakPolarHBondContact CB-ND2 3.3Å; L506-N511 WeakPolarHBondContact CB-OD1 3.42Å; L506-N511 WeakPolarHBondContact CD1-OD1 3.34Å; L506-N511 PolarHBondContact O-ND2 3.19Å; L506-N511 VanDerWaalsContact O-ND2 3.14Å
507T64.1Low77.7Confident80 Ų8063.9 Ų63.949%0.49132%0.319SS..  trans-63.2148.8177.862.20000109.8E509 E510 N511T507-E509 PolarHBondContact O-N 2.9Å; T507-E510 WeakPolarHBondContact CB-OE2 3.49Å; T507-E510 WeakPolarHBondContact CG2-OE2 3.31Å; T507-E510 PolarHBondContact N-OE2 3.17Å; T507-E510 PolarHBondContact O-N 3.33Å; T507-E510 WeakPolarHBondContact OG1-CB 3.3Å; T507-E510 WeakPolarHBondContact OG1-CG 3.38Å; T507-E510 PolarHBondContact OG1-N 3.5Å; T507-E510 PolarHBondContact OG1-OE2 2.91Å; T507-N511 PolarHBondContact O-N 3.45Å; T507-N511 VanDerWaalsContact O-N 3.1Å; T507-N511 PolarHBondContact O-ND2 3Å
508K63.2Low76.7Confident65 Ų6565.9 Ų65.928%0.28334%0.337SS..Hα-helixtrans-45.3-40172.8172.5175.4157.81800112.5Q258 D259 V260 K512Q258-K508 WeakPolarHBondContact O-CE 3.37Å; Q258-K508 PolarHBondContact O-NZ 2.99Å; D259-K508 VanDerWaalsContact C-NZ 3.27Å; D259-K508 PolarHBondContact O-NZ 3.11Å; D259-K508 VanDerWaalsContact O-NZ 3.13Å; V260-K508 PolarHBondContact O-NZ 3.31Å; K508-K512 VanDerWaalsContact O-CB 3.3Å; K508-K512 WeakPolarHBondContact O-CB 3.48Å; K508-K512 PolarHBondContact O-N 3.39Å
509E65.8Low75.5Confident116 Ų11666.5 Ų66.554%0.54234%0.339SS..Hα-helixtrans-69.5-45.9180-165.162.3-16100112.6T507 N511 K512 N513T507-E509 PolarHBondContact O-N 2.9Å; E509-N511 VanDerWaalsContact C-N 3.31Å; E509-N511 PolarHBondContact O-N 3.02Å; E509-K512 PolarHBondContact O-N 3.28Å; E509-N513 VanDerWaalsContact O-CB 3.31Å; E509-N513 WeakPolarHBondContact O-CB 3.38Å; E509-N513 PolarHBondContact O-N 2.99Å; E509-N513 PolarHBondContact O-ND2 3.37Å
510E67.8Low74Confident95 Ų9566.9 Ų66.944%0.44434%0.341SS..Hα-helixtrans-59.9-42.5177-74.1162.9145.800111.5L506 T507 N513 I514L506-E510 HydrophobicContact CD2-CB 4.49Å; T507-E510 WeakPolarHBondContact CB-OE2 3.49Å; T507-E510 WeakPolarHBondContact CG2-OE2 3.31Å; T507-E510 PolarHBondContact N-OE2 3.17Å; T507-E510 PolarHBondContact O-N 3.33Å; T507-E510 WeakPolarHBondContact OG1-CB 3.3Å; T507-E510 WeakPolarHBondContact OG1-CG 3.38Å; T507-E510 PolarHBondContact OG1-N 3.5Å; T507-E510 PolarHBondContact OG1-OE2 2.91Å; E510-N513 PolarHBondContact O-N 3.34Å; E510-I514 WeakPolarHBondContact O-CD1 3.49Å; E510-I514 VanDerWaalsContact O-CG1 3.24Å; E510-I514 WeakPolarHBondContact O-CG1 2.76Å; E510-I514 PolarHBondContact O-N 3.08Å
511N66.1Low72.1Confident1 Ų174.3 Ų74.31%0.00537%0.374CS..Hα-helixtrans-72.5-41.6-179.6-68.7-45.5000113.5F251 L506 T507 E509 N513 I514 L515F251-N511 HydrophobicContact CD2-CB 3.97Å; F251-N511 VanDerWaalsContact CD2-CG 3.47Å; F251-N511 WeakPolarHBondContact CD2-ND2 3.48Å; F251-N511 HydrophobicContact CE2-CB 3.08Å; F251-N511 WeakPolarHBondContact CE2-ND2 3.32Å; F251-N511 HydrophobicContact CZ-CB 3.53Å; L506-N511 VanDerWaalsContact CB-CG 3.5Å; L506-N511 WeakPolarHBondContact CB-ND2 3.3Å; L506-N511 WeakPolarHBondContact CB-OD1 3.42Å; L506-N511 WeakPolarHBondContact CD1-OD1 3.34Å; L506-N511 PolarHBondContact O-ND2 3.19Å; L506-N511 VanDerWaalsContact O-ND2 3.14Å; T507-N511 PolarHBondContact O-N 3.45Å; T507-N511 VanDerWaalsContact O-N 3.1Å; T507-N511 PolarHBondContact O-ND2 3Å; E509-N511 VanDerWaalsContact C-N 3.31Å; E509-N511 PolarHBondContact O-N 3.02Å; N511-N513 PolarHBondContact O-N 3.45Å; N511-I514 PolarHBondContact O-N 2.9Å; N511-I514 VanDerWaalsContact O-N 3.1Å; N511-L515 WeakPolarHBondContact O-CG 3.21Å; N511-L515 PolarHBondContact O-N 2.83Å
512K68.9Low69.9Low79 Ų7979.3 Ų79.334%0.34340%0.401SS..Hα-helixtrans-58.8-41.7174.3-171.2171.7-176.7171.40110.2D259 K508 E509 I514 L515 Q516D259-K512 IonicContact OD1-NZ 3.93Å; K508-K512 VanDerWaalsContact O-CB 3.3Å; K508-K512 WeakPolarHBondContact O-CB 3.48Å; K508-K512 PolarHBondContact O-N 3.39Å; E509-K512 PolarHBondContact O-N 3.28Å; K512-I514 PolarHBondContact O-N 3.1Å; K512-L515 PolarHBondContact O-N 2.82Å; K512-Q516 VanDerWaalsContact O-CB 3.28Å; K512-Q516 WeakPolarHBondContact O-CB 3.43Å; K512-Q516 VanDerWaalsContact O-CG 3.23Å; K512-Q516 WeakPolarHBondContact O-CG 3.14Å; K512-Q516 PolarHBondContact O-N 3.42Å
513N75.5Confident67.6Low83 Ų8380.3 Ų80.344%0.44440%0.402SS..Hα-helixtrans-63.5-37.7174.7-72.3-33.8000112.8E509 E510 N511 Q516 M517E509-N513 VanDerWaalsContact O-CB 3.31Å; E509-N513 WeakPolarHBondContact O-CB 3.38Å; E509-N513 PolarHBondContact O-N 2.99Å; E509-N513 PolarHBondContact O-ND2 3.37Å; E510-N513 PolarHBondContact O-N 3.34Å; N511-N513 PolarHBondContact O-N 3.45Å; N513-Q516 CarbonylContact O-C 3.43Å; N513-Q516 PolarHBondContact O-N 2.69Å; N513-M517 PolarHBondContact O-N 3Å
514I72.9Confident65.3Low33 Ų3381.2 Ų81.217%0.16940%0.404CS..Hα-helixtrans-66.8-43.8176.1-68.2160.1000111.5L241 L242 I245 E510 N511 K512 Q516 M517L241-I514 HydrophobicContact CD2-CD1 4.16Å; L241-I514 HydrophobicContact CD2-CG1 4.31Å; L241-I514 HydrophobicContact CD2-CG2 3.87Å; L241-I514 HydrophobicContact CG-CG2 4.16Å; L242-I514 HydrophobicContact CD2-CG2 4.01Å; I245-I514 HydrophobicContact CD1-CB 4.1Å; I245-I514 HydrophobicContact CD1-CD1 3.98Å; I245-I514 HydrophobicContact CD1-CG2 3.48Å; I245-I514 VanDerWaalsContact CD1-CG2 3.48Å; E510-I514 WeakPolarHBondContact O-CD1 3.49Å; E510-I514 VanDerWaalsContact O-CG1 3.24Å; E510-I514 WeakPolarHBondContact O-CG1 2.76Å; E510-I514 PolarHBondContact O-N 3.08Å; N511-I514 PolarHBondContact O-N 2.9Å; N511-I514 VanDerWaalsContact O-N 3.1Å; K512-I514 PolarHBondContact O-N 3.1Å; I514-Q516 VanDerWaalsContact C-N 3.26Å; I514-Q516 PolarHBondContact O-N 3.16Å; I514-M517 WeakPolarHBondContact O-CB 3.33Å; I514-M517 PolarHBondContact O-N 3.12Å
515L77.2Confident63.1Low13 Ų1386.3 Ų86.37%0.06843%0.429CS..Hα-helixtrans-67.3-29.7177.4-64.6180000112.4V128 S130 H132 L242 I245 F251 F255 N511 K512V128-L515 WeakPolarHBondContact O-CD2 3.25Å; S130-L515 PolarHBondContact OG-O 3.38Å; H132-L515 PolarHBondContact ND1-O 3.23Å; L242-L515 HydrophobicContact CD2-CD2 3.79Å; I245-L515 HydrophobicContact CG2-CD2 4.48Å; F251-L515 HydrophobicContact CE1-CD1 4.45Å; F251-L515 HydrophobicContact CZ-CD1 4.3Å; F255-L515 HydrophobicContact CE2-CD1 3.87Å; F255-L515 HydrophobicContact CZ-CD1 4.43Å; N511-L515 WeakPolarHBondContact O-CG 3.21Å; N511-L515 PolarHBondContact O-N 2.83Å; K512-L515 PolarHBondContact O-N 2.82Å
516Q74.9Confident61.8Low106 Ų10682.9 Ų82.950%0.49541%0.414SS..THydrogen-bonded Turntrans-88.4-3.8177.8-68.8-178.4-8.800114.1H132 K512 N513 I514 A518H132-Q516 VanDerWaalsContact CE1-C 3.49Å; H132-Q516 WeakPolarHBondContact CE1-CA 3.42Å; H132-Q516 PolarHBondContact CE1-O 2.96Å; H132-Q516 PolarHBondContact NE2-O 3.3Å; K512-Q516 VanDerWaalsContact O-CB 3.28Å; K512-Q516 WeakPolarHBondContact O-CB 3.43Å; K512-Q516 VanDerWaalsContact O-CG 3.23Å; K512-Q516 WeakPolarHBondContact O-CG 3.14Å; K512-Q516 PolarHBondContact O-N 3.42Å; N513-Q516 CarbonylContact O-C 3.43Å; N513-Q516 PolarHBondContact O-N 2.69Å; I514-Q516 VanDerWaalsContact C-N 3.26Å; I514-Q516 PolarHBondContact O-N 3.16Å; Q516-A518 PolarHBondContact O-N 3.06Å
517M76.6Confident60.5Low99 Ų9987 Ų8749%0.48843%0.432SS..SBendtrans-69.4125179.8-162.4171.183.700109.6Q238 N513 I514 F519Q238-M517 HydrophobicContact CG-CE 3.92Å; Q238-M517 PolarHBondContact NE2-O 3.21Å; N513-M517 PolarHBondContact O-N 3Å; I514-M517 WeakPolarHBondContact O-CB 3.33Å; I514-M517 PolarHBondContact O-N 3.12Å; M517-F519 PolarHBondContact O-N 2.91Å
518A74Confident58.9Low48 Ų4889.2 Ų89.240%0.39744%0.44SS..  trans-53.6135.8176.800000110.5Q238 Q516 L520Q238-A518 PolarHBondContact NE2-O 3.29Å; Q516-A518 PolarHBondContact O-N 3.06Å; A518-L520 WeakPolarHBondContact CB-O 3.23Å; A518-L520 PolarHBondContact O-N 2.74Å
519F69.2Low57.6Low12 Ų1294.2 Ų94.25%0.05346%0.462CS..SBendtrans-70.7-22.9-178.6-172.4-125.6000112.5L20 H132 V133 I140 M235 I239 M517L20-F519 HydrophobicContact CD1-CE1 4.38Å; L20-F519 HydrophobicContact CD1-CE2 4.47Å; L20-F519 HydrophobicContact CD1-CZ 3.72Å; L20-F519 HydrophobicContact CD2-CE1 4.18Å; L20-F519 HydrophobicContact CD2-CZ 3.89Å; L20-F519 HydrophobicContact CG-CZ 4.46Å; H132-F519 HydrophobicContact CB-CB 4.38Å; H132-F519 WeakPolarHBondContact O-CB 2.95Å; V133-F519 HydrophobicContact CG2-CD2 4.07Å; V133-F519 HydrophobicContact CG2-CE2 4.33Å; V133-F519 HydrophobicContact CG2-CG 4.47Å; I140-F519 HydrophobicContact CD1-CE1 4.49Å; M235-F519 HydrophobicContact CB-CE2 4.46Å; M235-F519 HydrophobicContact CE-CD1 3.64Å; M235-F519 HydrophobicContact CE-CD2 4.32Å; M235-F519 HydrophobicContact CE-CE1 3.14Å; M235-F519 HydrophobicContact CE-CE2 3.87Å; M235-F519 HydrophobicContact CE-CG 4.21Å; M235-F519 HydrophobicContact CE-CZ 3.26Å; I239-F519 HydrophobicContact CD1-CD2 4.23Å; I239-F519 HydrophobicContact CD1-CE2 3.41Å; I239-F519 VanDerWaalsContact CD1-CE2 3.41Å; I239-F519 HydrophobicContact CD1-CZ 3.97Å; I239-F519 HydrophobicContact CG1-CE2 3.76Å; I239-F519 HydrophobicContact CG1-CZ 4.23Å; M517-F519 PolarHBondContact O-N 2.91Å
520L64.8Low56Low81 Ų8194.3 Ų94.342%0.42447%0.467SS..SBendtrans-131.8134.3169-70.6168.1000108.9I139 L227 M235 A518I139-L520 HydrophobicContact CD1-CD1 3.74Å; I139-L520 HydrophobicContact CD1-CD2 4.04Å; I139-L520 HydrophobicContact CD1-CG 4.2Å; L227-L520 HydrophobicContact CD2-CD2 4.43Å; M235-L520 HydrophobicContact CE-CD2 3.71Å; M235-L520 HydrophobicContact CE-CG 4.15Å; M235-L520 HydrophobicContact SD-CD2 3.71Å; A518-L520 WeakPolarHBondContact CB-O 3.23Å; A518-L520 PolarHBondContact O-N 2.74Å
521Q52.7Low54.5Low169 Ų16994.9 Ų94.979%0.7948%0.476SS*.  trans-84.5111.4161.7-92.3170.6-33.500107.6D523Q521-D523 PolarHBondContact O-N 3.08Å
522D45.2Very low53.1Low114 Ų114100.2 Ų100.261%0.6151%0.513SS*.  trans-63.9107.2168.9-149.96.9000106.4K524D522-K524 PolarHBondContact O-N 2.65Å; D522-K524 IonicContact OD1-NZ 2.79Å; D522-K524 WeakPolarHBondContact OD2-CD 3.45Å; D522-K524 WeakPolarHBondContact OD2-CE 3.25Å; D522-K524 IonicContact OD2-NZ 3.86Å; D522-K524 PolarHBondContact OD2-NZ 3.24Å
523D42.3Very low51.7Low91 Ų91100.5 Ų100.549%0.48752%0.524SS..THydrogen-bonded Turntrans-71.425.8-173.9-125.41000112.2Q521 D525 K526Q521-D523 PolarHBondContact O-N 3.08Å; D523-D525 PolarHBondContact O-N 3.02Å; D523-K526 PolarHBondContact O-N 3.49Å; D523-K526 IonicContact OD1-NZ 3.08Å; D523-K526 PolarHBondContact OD1-NZ 3.09Å; D523-K526 IonicContact OD2-NZ 2.61Å; D523-K526 PolarHBondContact OD2-NZ 3.22Å
524K39.7Very low50Low138 Ų138102.5 Ų102.560%0.654%0.539SS*.Hα-helixtrans-64.6-18.2177.4-73.1-174.5179.61360113.2D522D522-K524 PolarHBondContact O-N 2.65Å; D522-K524 IonicContact OD1-NZ 2.79Å; D522-K524 WeakPolarHBondContact OD2-CD 3.45Å; D522-K524 WeakPolarHBondContact OD2-CE 3.25Å; D522-K524 IonicContact OD2-NZ 3.86Å; D522-K524 PolarHBondContact OD2-NZ 3.24Å
525D36.6Very low48.1Very low130 Ų130112.5 Ų112.570%0.69559%0.588SS**Hα-helixtrans-82.2-9176.9-79.5-19.5000114.4D523D523-D525 PolarHBondContact O-N 3.02Å
526K38.4Very low46.6Very low124 Ų124117.5 Ų117.554%0.53961%0.614SS.*Hα-helixtrans-86.3-27.2172.9-75.5-164.7-167.8105.70113.5D523D523-K526 PolarHBondContact O-N 3.49Å; D523-K526 IonicContact OD1-NZ 3.08Å; D523-K526 PolarHBondContact OD1-NZ 3.09Å; D523-K526 IonicContact OD2-NZ 2.61Å; D523-K526 PolarHBondContact OD2-NZ 3.22Å
527E33.8Very low45.1Very low151 Ų151118.1 Ų118.171%0.70662%0.621SS**Hα-helixtrans-70.1-33174.9-81.9-171.7148.300112.1K529 V531E527-K529 PolarHBondContact O-N 2.98Å; E527-V531 WeakPolarHBondContact O-CG2 3.42Å
528N32.3Very low43.4Very low125 Ų125119.2 Ų119.267%0.66863%0.628SS**Hα-helixtrans-78.3-14.1178.6-100.5-10.7000115.1
529K34.3Very low41.6Very low171 Ų171123.4 Ų123.474%0.74364%0.642SS**Hα-helixtrans-89.2-19.7173.9-81-178.8178.9169.70113.8E527E527-K529 PolarHBondContact O-N 2.98Å
530N33.6Very low39.9Very low118 Ų118130.3 Ų130.363%0.63168%0.678SS**Hα-helixtrans-90.2-13.5176.2-79.4-14.1000113.8
531V35.5Very low38.2Very low106 Ų106133.6 Ų133.664%0.64270%0.695SS**SBendtrans-84.3-22.5174.7179.60000112.3E527E527-V531 WeakPolarHBondContact O-CG2 3.42Å
532C36.4Very low37.2Very low114 Ų114131.1 Ų131.177%0.7769%0.689SS**THydrogen-bonded Turntrans-88.36.3174.9-88.80000115.1
533S38.9Very low36.6Very low85 Ų85132.4 Ų132.459%0.59470%0.695SS**THydrogen-bonded Turntrans-117.111.1172.986.90000114.2
534V39.6Very low36.1Very low124 Ų124135.8 Ų135.875%0.75271%0.712SS**  trans-132.334.6174.8-162.50000111.4
535M33.6Very low35.7Very low244 Ų244135.6 Ų135.6100%1.20272%0.722SS**  trans-135.70160.4-113.6-178170.900107.8

Retrieved 535 of 535 residues in 1083.8 ms (Link to these results)