A0A087XX51_POEFO Loading...

Solute carrier family 38 member 4

AlphaFold DB , UniProt , Accession A0A087XX51, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 544 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	40.2	Very low	29.2	Very low	246 Å²	246	176.3 Å²	176.3	100%	1.212	89%	0.892	S	S	*	*				0	111.1	0	-78.2	177.4	167.1	0	0	109.3
2	P	32.5	Very low	28.7	Very low	129 Å²	129	181.7 Å²	181.7	84%	0.838	89%	0.894	S	S	*	*			trans	-115.9	142.4	154.4	27.8	-12	0	0	0	111
3	G	29	Very low	28.5	Very low	80 Å²	80	176.4 Å²	176.4	83%	0.825	88%	0.878	S	S	*	*			trans	-72.2	143.3	-169.4	0	0	0	0	0	114.9	R5	G3-R5 PolarHBondContact O-N 2.71Å
4	V	29.5	Very low	28.2	Very low	136 Å²	136	171 Å²	171	82%	0.824	86%	0.862	S	S	*	*			trans	-67.7	117.4	172.6	175.5	0	0	0	0	108.9	E6	V4-E6 PolarHBondContact O-N 3.15Å
5	R	28.9	Very low	28.1	Very low	237 Å²	237	172.4 Å²	172.4	89%	0.894	87%	0.868	S	S	*	*			trans	-75.4	112.3	157.8	-93.3	-178.8	178.1	-170.8	-0.8	106.9	G3 L7	G3-R5 PolarHBondContact O-N 2.71Å; R5-L7 PolarHBondContact O-N 2.97Å; R5-L7 VanDerWaalsContact O-N 3.15Å
6	E	29.1	Very low	28	Very low	188 Å²	188	172.7 Å²	172.7	88%	0.879	87%	0.865	S	S	*	*			trans	-66	110.4	164.4	-82.3	-170.6	143.4	0	0	108.8	V4 M8	V4-E6 PolarHBondContact O-N 3.15Å; E6-M8 PolarHBondContact O-N 2.9Å
7	L	28.6	Very low	28.2	Very low	162 Å²	162	167.6 Å²	167.6	85%	0.848	86%	0.856	S	S	*	*			trans	-64.6	114.2	161.8	-106.8	115.8	0	0	0	107.6	R5 E9	R5-L7 PolarHBondContact O-N 2.97Å; R5-L7 VanDerWaalsContact O-N 3.15Å; L7-E9 PolarHBondContact O-N 3.07Å
8	M	29.1	Very low	28.2	Very low	185 Å²	185	163.1 Å²	163.1	91%	0.911	83%	0.834	S	S	*	*			trans	-69.9	99	169.6	-158.9	177	-91.7	0	0	107.4	E6 L10	E6-M8 PolarHBondContact O-N 2.9Å; M8-L10 PolarHBondContact O-N 2.71Å
9	E	26.3	Very low	28.3	Very low	181 Å²	181	162.3 Å²	162.3	85%	0.846	83%	0.832	S	S	*	*			trans	-57.8	124.6	178.5	-79	-161.2	147.2	0	0	111	L7 R11	L7-E9 PolarHBondContact O-N 3.07Å; E9-R11 PolarHBondContact O-N 3.33Å
10	L	25	Very low	28.4	Very low	171 Å²	171	162.3 Å²	162.3	90%	0.895	83%	0.834	S	S	*	*			trans	-63.1	101.6	165.7	-101.6	100.4	0	0	0	109.2	M8 R12	M8-L10 PolarHBondContact O-N 2.71Å; L10-R12 PolarHBondContact O-N 2.96Å
11	R	22.5	Very low	28.5	Very low	224 Å²	224	159 Å²	159	85%	0.845	83%	0.825	S	S	*	*			trans	-74.1	106.2	166.3	-164.7	174.4	-166.8	-178.7	3.5	109	E9 V13	E9-R11 PolarHBondContact O-N 3.33Å; R11-V13 HydrophobicContact CG-CG2 4.33Å; R11-V13 PolarHBondContact O-N 3.24Å; R11-V13 VanDerWaalsContact O-N 3.09Å
12	R	23.5	Very low	28.1	Very low	241 Å²	241	154.4 Å²	154.4	91%	0.909	81%	0.811	S	S	*	*			trans	-61	106.9	162.9	-89.7	-172.3	-99.1	172.1	-6.7	108.4	L10	L10-R12 PolarHBondContact O-N 2.96Å
13	V	25.9	Very low	27.9	Very low	113 Å²	113	152.4 Å²	152.4	69%	0.685	81%	0.805	S	S	*	*			trans	-98.3	118.8	165.5	-178.3	0	0	0	0	106.5	R11	R11-V13 HydrophobicContact CG-CG2 4.33Å; R11-V13 PolarHBondContact O-N 3.24Å; R11-V13 VanDerWaalsContact O-N 3.09Å
14	P	24.2	Very low	27.8	Very low	101 Å²	101	154 Å²	154	66%	0.656	80%	0.804	S	S	*	*			trans	-59.3	143.2	173.8	-15.9	28.3	0	0	0	109.7	E16	P14-E16 VanDerWaalsContact C-N 3.29Å; P14-E16 PolarHBondContact O-N 2.87Å
15	M	27	Very low	27.7	Very low	192 Å²	192	155.8 Å²	155.8	95%	0.946	81%	0.808	S	S	*	*			trans	-63.3	99.2	157.4	-82.8	-156.2	-70.7	0	0	107	A17	M15-A17 PolarHBondContact O-N 3.4Å
16	E	27.4	Very low	27.6	Very low	177 Å²	177	153.8 Å²	153.8	83%	0.827	81%	0.809	S	S	*	*			trans	-60.1	123.4	170	-79.1	-179.5	157.3	0	0	108.7	P14 D18	P14-E16 VanDerWaalsContact C-N 3.29Å; P14-E16 PolarHBondContact O-N 2.87Å; E16-D18 PolarHBondContact O-N 2.9Å
17	A	30.2	Very low	27.4	Very low	87 Å²	87	153.3 Å²	153.3	72%	0.719	81%	0.807	S	S	*	*			trans	-65.5	116.7	161.1	0	0	0	0	0	107.1	M15 D19	M15-A17 PolarHBondContact O-N 3.4Å; A17-D19 PolarHBondContact O-N 3.49Å
18	D	29.2	Very low	27.2	Very low	86 Å²	86	154 Å²	154	46%	0.46	81%	0.805	S	S	.	*			trans	-60.8	102.3	162.9	-88.6	-57	0	0	0	106.6	E16 D20 K358	E16-D18 PolarHBondContact O-N 2.9Å; D18-D20 PolarHBondContact O-N 3.26Å; D18-K358 IonicContact OD1-NZ 2.98Å; D18-K358 PolarHBondContact OD1-NZ 3.11Å; D18-K358 IonicContact OD2-NZ 2.61Å
19	D	29.5	Very low	27	Very low	147 Å²	147	154.2 Å²	154.2	79%	0.786	80%	0.801	S	S	*	*			trans	-76.9	111.7	171.6	-145	6.1	0	0	0	107.9	A17	A17-D19 PolarHBondContact O-N 3.49Å
20	D	31.4	Very low	27	Very low	162 Å²	162	157.3 Å²	157.3	87%	0.866	81%	0.805	S	S	*	*			trans	-86.7	101.8	167.8	-100.9	-23.4	0	0	0	107.1	D18	D18-D20 PolarHBondContact O-N 3.26Å
21	S	30.3	Very low	26.9	Very low	94 Å²	94	152.3 Å²	152.3	66%	0.657	80%	0.795	S	S	*	*			trans	-144.5	101.6	162.6	64.5	0	0	0	0	111.8	A23	S21-A23 PolarHBondContact O-N 2.86Å
22	T	31.5	Very low	27.6	Very low	150 Å²	150	146.9 Å²	146.9	92%	0.92	79%	0.789	S	S	*	*			trans	-63.3	113.2	150.6	24.1	0	0	0	0	109.7
23	A	27.3	Very low	27.7	Very low	86 Å²	86	142.2 Å²	142.2	71%	0.711	78%	0.78	S	S	*	*			trans	-155.9	113.8	157	0	0	0	0	0	110.9	S21	S21-A23 PolarHBondContact O-N 2.86Å
24	S	26.9	Very low	27.7	Very low	114 Å²	114	143 Å²	143	80%	0.797	78%	0.78	S	S	*	*			trans	24.5	131.8	147.9	51.1	0	0	0	0	121.9
25	L	28	Very low	27.8	Very low	173 Å²	173	144 Å²	144	91%	0.906	79%	0.785	S	S	*	*			trans	-45.6	131.4	158	-78	114.6	0	0	0	113.4
26	E	25.8	Very low	27.7	Very low	196 Å²	196	143.5 Å²	143.5	92%	0.916	78%	0.78	S	S	*	*			trans	-165	131	135.5	-113.9	171.6	178.3	0	0	111.1
27	E	26.1	Very low	27.7	Very low	178 Å²	178	143.9 Å²	143.9	83%	0.832	78%	0.779	S	S	*	*			trans	-70.6	141.8	172.6	-66.3	174	121.9	0	0	111.5
28	H	24.7	Very low	27.4	Very low	176 Å²	176	144.5 Å²	144.5	82%	0.815	78%	0.778	S	S	*	*				-179.3	147.9	113.3	-124.1	60.9	0	0	0	114.6
29	F	24.9	Very low	27.3	Very low	189 Å²	189	147.4 Å²	147.4	83%	0.829	80%	0.799	S	S	*	*			trans	-58.3	146.1	-179.7	-87.9	-106.3	0	0	0	117.4
30	R	26.3	Very low	27.1	Very low	247 Å²	247	147.9 Å²	147.9	93%	0.932	80%	0.8	S	S	*	*				-177.4	123.9	116.8	-100.3	-179.5	-175.9	-166	1.8	111.3
31	G	23.3	Very low	26.8	Very low	66 Å²	66	144.3 Å²	144.3	68%	0.68	79%	0.793	S	S	*	*			trans	-84.3	-151.2	163.2	0	0	0	0	0	111.6
32	P	36.7	Very low	26.3	Very low	110 Å²	110	145.6 Å²	145.6	71%	0.714	80%	0.802	S	S	*	*			cis	-142.9	-179.3	-12.2	42.6	-24.5	0	0	0	115
33	I	26.2	Very low	26	Very low	142 Å²	142	143.2 Å²	143.2	73%	0.728	79%	0.791	S	S	*	*			trans	71.3	137.7	141	-75.3	161.8	0	0	0	116.9
34	D	25.5	Very low	25.7	Very low	129 Å²	129	148 Å²	148	69%	0.69	80%	0.799	S	S	*	*			cis	-163.5	143	20.2	-108.2	-11.7	0	0	0	109.1
35	V	24.7	Very low	25.5	Very low	124 Å²	124	153.3 Å²	153.3	75%	0.752	80%	0.803	S	S	*	*				68.9	118.3	98.5	-176.2	0	0	0	0	116
36	E	26.7	Very low	25.4	Very low	180 Å²	180	153 Å²	153	84%	0.841	80%	0.801	S	S	*	*				158.1	98.7	126.3	-160.3	165.4	-178.8	0	0	111
37	K	27.4	Very low	25.3	Very low	185 Å²	185	150.2 Å²	150.2	80%	0.804	79%	0.792	S	S	*	*				63.1	102.2	94.7	-108.9	-175.1	-176.5	177.9	0	117.5
38	S	23.6	Very low	25.3	Very low	100 Å²	100	149.7 Å²	149.7	70%	0.699	79%	0.79	S	S	*	*				40.1	124.7	129.6	64.8	0	0	0	0	121.7
39	T	26.2	Very low	25.3	Very low	147 Å²	147	148.9 Å²	148.9	90%	0.902	79%	0.791	S	S	*	*				-155.7	142.1	128.1	-21.9	0	0	0	0	112.5
40	I	25.8	Very low	25.4	Very low	158 Å²	158	147.2 Å²	147.2	81%	0.81	79%	0.791	S	S	*	*			trans	-108.4	148.6	177.6	-70.7	167.6	0	0	0	108.4
41	A	24.1	Very low	25.3	Very low	86 Å²	86	142.8 Å²	142.8	71%	0.711	79%	0.786	S	S	*	*			trans	137.2	108.1	148.5	0	0	0	0	0	110.6
42	S	21.3	Very low	25.6	Very low	122 Å²	122	143.4 Å²	143.4	85%	0.853	79%	0.792	S	S	*	*				70.6	116.8	74.4	-64	0	0	0	0	115.3
43	S	23.5	Very low	25.1	Very low	99 Å²	99	147.1 Å²	147.1	69%	0.692	80%	0.8	S	S	*	*			trans	144	132.6	160	-171.7	0	0	0	0	107
44	Q	23	Very low	25	Very low	186 Å²	186	147 Å²	147	87%	0.869	80%	0.801	S	S	*	*			cis	-171.1	155.8	40.4	-139.7	148.3	-19.3	0	0	109.4
45	Y	22.8	Very low	25.2	Very low	226 Å²	226	148.7 Å²	148.7	89%	0.886	81%	0.81	S	S	*	*			trans	-84.1	173.7	173.8	-90.3	-96.4	0	0	0	113.1
46	I	26	Very low	25.4	Very low	168 Å²	168	153.6 Å²	153.6	86%	0.862	82%	0.815	S	S	*	*			trans	104	140.3	169.8	-56.2	166.4	0	0	0	111.3
47	D	23.2	Very low	25.4	Very low	137 Å²	137	154.8 Å²	154.8	73%	0.733	82%	0.818	S	S	*	*			cis	175.8	165.5	-28	-171.7	11.1	0	0	0	103.9
48	E	25.9	Very low	25.5	Very low	167 Å²	167	153.8 Å²	153.8	78%	0.78	82%	0.82	S	S	*	*			trans	91.2	116.3	163.5	-56.7	-164.9	132.9	0	0	121
49	N	23.6	Very low	25.6	Very low	159 Å²	159	154 Å²	154	85%	0.85	82%	0.822	S	S	*	*			trans	-11.1	139.8	156.3	-57.7	-28.9	0	0	0	119.9
50	D	27.2	Very low	25.6	Very low	153 Å²	153	153.9 Å²	153.9	82%	0.818	82%	0.815	S	S	*	*				-166	149.1	124	-158.2	17.9	0	0	0	111.6
51	D	25.2	Very low	25.7	Very low	155 Å²	155	150.4 Å²	150.4	83%	0.829	82%	0.819	S	S	*	*			trans	-80.8	158.8	-176.3	-58.1	-52.7	0	0	0	112.5
52	G	28.5	Very low	25.9	Very low	79 Å²	79	153.4 Å²	153.4	81%	0.814	82%	0.822	S	S	*	*			trans	158.7	124.5	165.1	0	0	0	0	0	116.4
53	E	26.2	Very low	26.3	Very low	188 Å²	188	155.7 Å²	155.7	88%	0.879	82%	0.822	S	S	*	*			trans	-71.5	161.9	-172.8	-63	171.8	131.5	0	0	116
54	D	25.7	Very low	26.3	Very low	140 Å²	140	160.8 Å²	160.8	75%	0.749	83%	0.831	S	S	*	*			trans	57.1	112.2	152.9	-84.4	-20.2	0	0	0	120.3
55	D	27.9	Very low	26.4	Very low	163 Å²	163	161.2 Å²	161.2	87%	0.872	83%	0.83	S	S	*	*				-159.5	131.1	115.6	-103.9	-28.8	0	0	0	113.5
56	R	30.2	Very low	26.5	Very low	228 Å²	228	158 Å²	158	86%	0.86	82%	0.821	S	S	*	*			trans	-67.1	125.2	177.1	-69.7	170.8	175.8	176.5	-0.6	110.7
57	F	26	Very low	26.4	Very low	204 Å²	204	160 Å²	160	90%	0.895	82%	0.823	S	S	*	*			trans	-139	130.4	153.4	-108.4	-90.1	0	0	0	112.6
58	L	29.3	Very low	26.8	Very low	165 Å²	165	162.2 Å²	162.2	86%	0.864	82%	0.823	S	S	*	*			trans	-53	137.7	-171.9	-65.1	147.7	0	0	0	114
59	S	25.9	Very low	27	Very low	104 Å²	104	163.5 Å²	163.5	73%	0.727	83%	0.829	S	S	*	*			trans	-177.1	118.8	132	-177.7	0	0	0	0	111.3
60	N	27.3	Very low	27.5	Very low	144 Å²	144	165 Å²	165	77%	0.77	83%	0.83	S	S	*	*			trans	39.2	109.5	147.2	-65.2	-21.5	0	0	0	118.2	L62	N60-L62 PolarHBondContact O-N 3.19Å
61	G	27.5	Very low	28.2	Very low	86 Å²	86	163 Å²	163	89%	0.887	82%	0.816	S	S	*	*			trans	-57.8	83.2	159.9	0	0	0	0	0	111.4	M63	G61-M63 PolarHBondContact O-N 2.9Å; G61-M63 VanDerWaalsContact O-N 3.15Å
62	L	28.9	Very low	28.8	Very low	149 Å²	149	163.3 Å²	163.3	78%	0.78	81%	0.813	S	S	*	*			trans	-63.5	110.3	163.5	-164.5	157.7	0	0	0	105.5	N60 K64	N60-L62 PolarHBondContact O-N 3.19Å; L62-K64 PolarHBondContact O-N 3.49Å; L62-K64 VanDerWaalsContact O-N 3.07Å
63	M	27.9	Very low	29.8	Very low	170 Å²	170	166 Å²	166	84%	0.837	80%	0.799	S	S	*	*			trans	-37.2	119.4	172.2	-82.8	-156.3	162	0	0	109.6	G61 K65	G61-M63 PolarHBondContact O-N 2.9Å; G61-M63 VanDerWaalsContact O-N 3.15Å; M63-K65 VanDerWaalsContact C-N 3.3Å; M63-K65 PolarHBondContact O-N 3.01Å
64	K	23.4	Very low	31.2	Very low	206 Å²	206	163.4 Å²	163.4	90%	0.896	79%	0.787	S	S	*	*			trans	-45	99.7	166.1	-85.4	177.6	172.7	173.6	0	108	L62 K66	L62-K64 PolarHBondContact O-N 3.49Å; L62-K64 VanDerWaalsContact O-N 3.07Å; K64-K66 VanDerWaalsContact C-N 3.33Å; K64-K66 PolarHBondContact O-N 3.48Å
65	K	25.6	Very low	33	Very low	195 Å²	195	160.5 Å²	160.5	85%	0.848	78%	0.776	S	S	*	*			trans	-57.4	105.2	164.2	-104.1	-179.3	174.1	176.9	0	104.1	M63 K67	M63-K65 VanDerWaalsContact C-N 3.3Å; M63-K65 PolarHBondContact O-N 3.01Å; K65-K67 PolarHBondContact O-N 3.36Å
66	K	25.3	Very low	35.2	Very low	159 Å²	159	153.5 Å²	153.5	69%	0.691	74%	0.742	S	S	*	*			trans	-51.6	114.1	163.1	-86.6	-177.7	174.8	179.3	0	105.6	K64 Y68	K64-K66 VanDerWaalsContact C-N 3.33Å; K64-K66 PolarHBondContact O-N 3.48Å; K66-Y68 HydrophobicContact CB-CD2 4Å; K66-Y68 HydrophobicContact CB-CE2 3.71Å; K66-Y68 HydrophobicContact CD-CE2 4.36Å; K66-Y68 WeakPolarHBondContact O-CD2 3.43Å; K66-Y68 PolarHBondContact O-N 3.19Å
67	K	24.8	Very low	37.7	Very low	209 Å²	209	150.9 Å²	150.9	91%	0.909	74%	0.739	S	S	*	*			trans	-65.5	88.7	171.7	-157.5	178.3	-174	-177.4	0	105.6	K65	K65-K67 PolarHBondContact O-N 3.36Å
68	Y	31	Very low	40.6	Very low	183 Å²	183	141.6 Å²	141.6	72%	0.718	70%	0.7	S	S	*	*			trans	-73.5	135.2	169.1	-79.2	-82.5	0	0	0	107	K66 E70	K66-Y68 HydrophobicContact CB-CD2 4Å; K66-Y68 HydrophobicContact CB-CE2 3.71Å; K66-Y68 HydrophobicContact CD-CE2 4.36Å; K66-Y68 WeakPolarHBondContact O-CD2 3.43Å; K66-Y68 PolarHBondContact O-N 3.19Å; Y68-E70 PolarHBondContact O-N 3.25Å
69	E	30.7	Very low	43.5	Very low	194 Å²	194	136.6 Å²	136.6	91%	0.907	68%	0.679	S	S	*	*			trans	-47.4	109.5	174.8	-68.4	164.3	157.9	0	0	109.3	E71	E69-E71 PolarHBondContact O-N 3.29Å
70	E	33.5	Very low	46.7	Very low	190 Å²	190	135 Å²	135	89%	0.888	66%	0.659	S	S	*	*			trans	-67.7	114.6	168.6	-75.7	176	167.5	0	0	106.8	Y68 E72	Y68-E70 PolarHBondContact O-N 3.25Å; E70-E72 PolarHBondContact O-N 2.78Å; E70-E72 VanDerWaalsContact O-N 3.09Å
71	E	42.1	Very low	49.8	Very low	111 Å²	111	129.6 Å²	129.6	52%	0.519	64%	0.637	S	S	.	*			trans	-55.1	115.4	173.4	-76.2	176.7	-177.5	0	0	108.4	E69 Y73 S138	E69-E71 PolarHBondContact O-N 3.29Å; E71-Y73 PolarHBondContact O-N 3.18Å; E71-S138 PolarHBondContact OE1-OG 3.43Å
72	E	37.3	Very low	52.8	Low	163 Å²	163	127.5 Å²	127.5	76%	0.762	61%	0.605	S	S	*	*			trans	-58	117	-178	-162	169.7	-174.5	0	0	110.1	E70 H74	E70-E72 PolarHBondContact O-N 2.78Å; E70-E72 VanDerWaalsContact O-N 3.09Å; E72-H74 PolarHBondContact O-N 2.83Å; E72-H74 VanDerWaalsContact O-N 3.11Å
73	Y	48.7	Very low	55.7	Low	135 Å²	135	120.4 Å²	120.4	53%	0.529	57%	0.568	S	S	.	*			trans	-76	98.5	-175.5	179.3	-95.5	0	0	0	110.6	E71 P75	E71-Y73 PolarHBondContact O-N 3.18Å; Y73-P75 HydrophobicContact CE1-CB 4.5Å
74	H	56.5	Low	58.9	Low	134 Å²	134	113 Å²	113	62%	0.62	53%	0.532	S	S	*	.	P	Polyproline II helix	trans	-85.3	124.6	165.8	-66.4	-62.4	0	0	0	110.1	E72 G76	E72-H74 PolarHBondContact O-N 2.83Å; E72-H74 VanDerWaalsContact O-N 3.11Å; H74-G76 PolarHBondContact O-N 3.41Å
75	P	64.4	Low	62.2	Low	79 Å²	79	107.6 Å²	107.6	51%	0.513	51%	0.509	S	S	.	.	P	Polyproline II helix	trans	-64.5	123.7	176.2	24.6	-30.7	0	0	0	110.1	Y73 H77	Y73-P75 HydrophobicContact CE1-CB 4.5Å; P75-H77 PolarHBondContact O-CD2 3.18Å
76	G	73.8	Confident	65.2	Low	16 Å²	16	99.1 Å²	99.1	17%	0.165	47%	0.473	C	S	.	.	P	Polyproline II helix	trans	-63.2	141.8	176.2	0	0	0	0	0	112.2	H74 E351 K353	H74-G76 PolarHBondContact O-N 3.41Å; G76-E351 CarbonylContact C-O 3.42Å; G76-E351 VanDerWaalsContact C-O 3.25Å; G76-E351 WeakPolarHBondContact CA-O 3.31Å; G76-K353 WeakPolarHBondContact O-CA 3.11Å
77	H	82.8	Confident	68.4	Low	172 Å²	172	91.5 Å²	91.5	80%	0.796	44%	0.44	S	S	*	.			trans	-103.5	-11.8	-178.5	-66.1	-79.6	0	0	0	113.6	P75 E351	P75-H77 PolarHBondContact O-CD2 3.18Å; H77-E351 PolarHBondContact N-O 2.89Å; H77-E351 VanDerWaalsContact N-O 3.14Å
78	A	85.1	Confident	71.7	Confident	9 Å²	9	81.7 Å²	81.7	7%	0.074	40%	0.397	C	S	.	.	B	Isolated β-bridge	trans	-74.4	132.3	-175	0	0	0	0	0	111.8	M82 E351 K353	A78-M82 HydrophobicContact CB-SD 4.43Å; A78-E351 HydrophobicContact CB-CB 4.21Å; A78-E351 VanDerWaalsContact CB-O 3.31Å; A78-E351 WeakPolarHBondContact CB-O 3.41Å; A78-E351 PolarHBondContact N-O 3.16Å; A78-K353 WeakPolarHBondContact O-CB 3.44Å; A78-K353 PolarHBondContact O-N 2.89Å
79	S	91.4	Very high	74.5	Confident	60 Å²	60	73.1 Å²	73.1	42%	0.42	36%	0.364	S	S	.	.			trans	-72.1	164.8	176.2	76.7	0	0	0	0	111.8	G81 M82 S83	S79-G81 PolarHBondContact O-N 3.17Å; S79-M82 PolarHBondContact O-N 3.19Å; S79-M82 WeakPolarHBondContact OG-CB 3.38Å; S79-M82 PolarHBondContact OG-N 3.45Å; S79-S83 PolarHBondContact O-N 2.94Å; S79-S83 PolarHBondContact O-OG 3.5Å
80	F	93.3	Very high	77.3	Confident	72 Å²	72	65.4 Å²	65.4	32%	0.316	33%	0.333	S	S	.	.	H	α-helix	trans	-57.3	-48	175.6	177.7	-92.4	0	0	0	111.8	S83 V84 K359 R362 V363 L366	F80-S83 WeakPolarHBondContact O-CB 3.21Å; F80-S83 PolarHBondContact O-N 3.27Å; F80-V84 HydrophobicContact CD1-CG2 4.35Å; F80-V84 HydrophobicContact CE1-CG2 3.98Å; F80-V84 HydrophobicContact CZ-CG2 4.26Å; F80-V84 WeakPolarHBondContact O-CG2 3.45Å; F80-V84 PolarHBondContact O-N 2.97Å; F80-K359 HydrophobicContact CD2-CG 3.98Å; F80-K359 HydrophobicContact CE2-CG 4.38Å; F80-R362 HydrophobicContact CE2-CB 4.14Å; F80-R362 HydrophobicContact CZ-CB 4.34Å; F80-V363 HydrophobicContact CD2-CG2 3.53Å; F80-V363 HydrophobicContact CE2-CB 4.43Å; F80-V363 HydrophobicContact CE2-CG2 3.39Å; F80-V363 HydrophobicContact CG-CG2 4.38Å; F80-V363 HydrophobicContact CZ-CG2 4.14Å; F80-L366 HydrophobicContact CE1-CD2 4.21Å
81	G	91.4	Very high	80.2	Confident	30 Å²	30	56.6 Å²	56.6	31%	0.309	29%	0.292	S	S	.	.	H	α-helix	trans	-65.9	-39.1	179.1	0	0	0	0	0	113.1	S79 S83 V84 F85	S79-G81 PolarHBondContact O-N 3.17Å; G81-S83 VanDerWaalsContact C-N 3.29Å; G81-S83 PolarHBondContact O-N 2.96Å; G81-V84 WeakPolarHBondContact O-CB 3.48Å; G81-V84 PolarHBondContact O-N 2.86Å; G81-F85 WeakPolarHBondContact O-CD2 3.38Å; G81-F85 WeakPolarHBondContact O-CG 3.33Å; G81-F85 PolarHBondContact O-N 3.49Å
82	M	90.1	Very high	82.5	Confident	41 Å²	41	51.3 Å²	51.3	20%	0.202	27%	0.267	C	S	.	.	H	α-helix	trans	-62.2	-38.7	175.1	-174.5	172	-76.2	0	0	111.8	A78 S79 V84 F85 N86 G226 Y227	A78-M82 HydrophobicContact CB-SD 4.43Å; S79-M82 PolarHBondContact O-N 3.19Å; S79-M82 WeakPolarHBondContact OG-CB 3.38Å; S79-M82 PolarHBondContact OG-N 3.45Å; M82-V84 VanDerWaalsContact C-N 3.35Å; M82-F85 PolarHBondContact O-N 3.32Å; M82-N86 WeakPolarHBondContact O-CB 3.3Å; M82-N86 PolarHBondContact O-N 3Å; M82-G226 VanDerWaalsContact CG-CA 3.5Å; M82-Y227 HydrophobicContact CE-CD2 4.4Å; M82-Y227 HydrophobicContact CE-CE1 4.48Å; M82-Y227 HydrophobicContact CE-CE2 3.98Å
83	S	91.5	Very high	84.5	Confident	0 Å²	0	43.9 Å²	43.9	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-66.6	-37	175.8	-53.9	0	0	0	0	112	S79 F80 G81 L87 L352	S79-S83 PolarHBondContact O-N 2.94Å; S79-S83 PolarHBondContact O-OG 3.5Å; F80-S83 WeakPolarHBondContact O-CB 3.21Å; F80-S83 PolarHBondContact O-N 3.27Å; G81-S83 VanDerWaalsContact C-N 3.29Å; G81-S83 PolarHBondContact O-N 2.96Å; S83-L87 WeakPolarHBondContact O-CB 3.33Å; S83-L87 PolarHBondContact O-N 2.94Å; S83-L352 VanDerWaalsContact OG-CD1 3.25Å; S83-L352 WeakPolarHBondContact OG-CD1 3.34Å
84	V	94.2	Very high	86.2	Confident	16 Å²	16	37.6 Å²	37.6	10%	0.097	21%	0.21	C	C	.	.	H	α-helix	trans	-63.7	-44.4	172.4	173	0	0	0	0	110.6	F80 G81 M82 L87 S88 V363 L366 S367	F80-V84 HydrophobicContact CD1-CG2 4.35Å; F80-V84 HydrophobicContact CE1-CG2 3.98Å; F80-V84 HydrophobicContact CZ-CG2 4.26Å; F80-V84 WeakPolarHBondContact O-CG2 3.45Å; F80-V84 PolarHBondContact O-N 2.97Å; G81-V84 WeakPolarHBondContact O-CB 3.48Å; G81-V84 PolarHBondContact O-N 2.86Å; M82-V84 VanDerWaalsContact C-N 3.35Å; V84-L87 PolarHBondContact O-N 3.38Å; V84-S88 WeakPolarHBondContact O-CB 3.4Å; V84-S88 PolarHBondContact O-N 3.29Å; V84-S88 PolarHBondContact O-OG 3.12Å; V84-V363 HydrophobicContact CG2-CB 4.29Å; V84-V363 HydrophobicContact CG2-CG1 3.93Å; V84-V363 HydrophobicContact CG2-CG2 4.26Å; V84-L366 HydrophobicContact CG1-CD2 4.31Å; V84-L366 HydrophobicContact CG1-CG 4.37Å; V84-L366 HydrophobicContact CG2-CD2 4.12Å; V84-S367 PolarHBondContact O-OG 3.48Å
85	F	91.8	Very high	87.5	Confident	92 Å²	92	31.3 Å²	31.3	40%	0.404	18%	0.181	S	C	.	.	H	α-helix	trans	-65.7	-42.3	177.5	-66.9	-40	0	0	0	112.9	G81 M82 S88 N89 L233	G81-F85 WeakPolarHBondContact O-CD2 3.38Å; G81-F85 WeakPolarHBondContact O-CG 3.33Å; G81-F85 PolarHBondContact O-N 3.49Å; M82-F85 PolarHBondContact O-N 3.32Å; F85-S88 PolarHBondContact O-N 3.02Å; F85-N89 WeakPolarHBondContact O-CB 3.46Å; F85-N89 PolarHBondContact O-N 3.08Å; F85-L233 HydrophobicContact CD1-CD2 3.48Å; F85-L233 VanDerWaalsContact CD1-CD2 3.48Å; F85-L233 HydrophobicContact CE1-CD2 3.82Å
86	N	90	Very high	88.7	Confident	16 Å²	16	27.5 Å²	27.5	9%	0.086	16%	0.157	C	C	.	.	H	α-helix	trans	-62.1	-47.2	175.9	-74.1	-7.4	0	0	0	111.4	M82 N89 A90 L225 G226 S229 I348	M82-N86 WeakPolarHBondContact O-CB 3.3Å; M82-N86 PolarHBondContact O-N 3Å; N86-N89 PolarHBondContact O-N 3.18Å; N86-A90 PolarHBondContact O-N 3.43Å; N86-L225 PolarHBondContact OD1-O 3.37Å; N86-G226 VanDerWaalsContact OD1-CA 3.31Å; N86-G226 WeakPolarHBondContact OD1-CA 3.49Å; N86-S229 VanDerWaalsContact OD1-CB 3.31Å; N86-S229 WeakPolarHBondContact OD1-CB 3.47Å; N86-S229 PolarHBondContact OD1-OG 2.93Å; N86-S229 VanDerWaalsContact OD1-OG 3.04Å; N86-I348 HydrophobicContact CB-CD1 3.97Å; N86-I348 HydrophobicContact CB-CG1 4.32Å
87	L	92.7	Very high	89.4	Confident	0 Å²	0	26.8 Å²	26.8	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-68.6	-37.1	179.5	-172.1	62.6	0	0	0	111.9	S83 V84 A90 I91 C341 V345 I348 M360 V363	S83-L87 WeakPolarHBondContact O-CB 3.33Å; S83-L87 PolarHBondContact O-N 2.94Å; V84-L87 PolarHBondContact O-N 3.38Å; L87-A90 PolarHBondContact O-N 3.26Å; L87-I91 HydrophobicContact CG-CD1 4.21Å; L87-I91 WeakPolarHBondContact O-CD1 3.28Å; L87-I91 VanDerWaalsContact O-CG1 3.3Å; L87-I91 WeakPolarHBondContact O-CG1 3.47Å; L87-I91 PolarHBondContact O-N 2.96Å; L87-C341 HydrophobicContact CD1-CB 3.76Å; L87-V345 HydrophobicContact CD1-CG2 4.05Å; L87-I348 HydrophobicContact CB-CD1 3.94Å; L87-I348 HydrophobicContact CD1-CD1 4.06Å; L87-M360 HydrophobicContact CD2-CE 4.32Å; L87-V363 HydrophobicContact CB-CG1 4.47Å; L87-V363 HydrophobicContact CD2-CG1 4.06Å
88	S	93.8	Very high	89.7	Confident	2 Å²	2	18.7 Å²	18.7	1%	0.014	11%	0.112	C	C	.	.	H	α-helix	trans	-62.7	-43.1	173.8	-63.2	0	0	0	0	111.4	V84 F85 A90 I91 M92	V84-S88 WeakPolarHBondContact O-CB 3.4Å; V84-S88 PolarHBondContact O-N 3.29Å; V84-S88 PolarHBondContact O-OG 3.12Å; F85-S88 PolarHBondContact O-N 3.02Å; S88-A90 VanDerWaalsContact C-N 3.31Å; S88-A90 PolarHBondContact O-N 3.04Å; S88-I91 PolarHBondContact O-N 3.3Å; S88-M92 WeakPolarHBondContact O-CB 3.4Å; S88-M92 PolarHBondContact O-N 2.64Å
89	N	90.1	Very high	90.1	Very high	4 Å²	4	18.2 Å²	18.2	2%	0.021	11%	0.108	C	C	.	.	H	α-helix	trans	-64.7	-36.3	176.6	-166.8	54.4	0	0	0	111.9	F85 N86 G93 S232 T422	F85-N89 WeakPolarHBondContact O-CB 3.46Å; F85-N89 PolarHBondContact O-N 3.08Å; N86-N89 PolarHBondContact O-N 3.18Å; N89-G93 PolarHBondContact O-N 2.99Å; N89-S232 VanDerWaalsContact OD1-CB 3.26Å; N89-S232 WeakPolarHBondContact OD1-CB 3.21Å; N89-S232 PolarHBondContact OD1-OG 2.98Å; N89-T422 PolarHBondContact ND2-OG1 2.9Å
90	A	89.7	Confident	90.3	Very high	31 Å²	31	15.4 Å²	15.4	26%	0.256	9%	0.088	S	C	.	.	H	α-helix	trans	-65.6	-37.6	174.4	0	0	0	0	0	112.9	N86 L87 S88 E344	N86-A90 PolarHBondContact O-N 3.43Å; L87-A90 PolarHBondContact O-N 3.26Å; S88-A90 VanDerWaalsContact C-N 3.31Å; S88-A90 PolarHBondContact O-N 3.04Å; A90-E344 HydrophobicContact CB-CB 4.11Å; A90-E344 HydrophobicContact CB-CG 3.9Å
91	I	93.7	Very high	90.3	Very high	5 Å²	5	13 Å²	13	3%	0.026	8%	0.077	C	C	.	.	H	α-helix	trans	-73.6	-54.5	176.3	-63.2	159.5	0	0	0	110	L87 S88 G93 A338 F339 C341 I368 M371 Y375	L87-I91 HydrophobicContact CG-CD1 4.21Å; L87-I91 WeakPolarHBondContact O-CD1 3.28Å; L87-I91 VanDerWaalsContact O-CG1 3.3Å; L87-I91 WeakPolarHBondContact O-CG1 3.47Å; L87-I91 PolarHBondContact O-N 2.96Å; S88-I91 PolarHBondContact O-N 3.3Å; I91-G93 PolarHBondContact O-N 2.7Å; I91-A338 WeakPolarHBondContact CG2-O 3.31Å; I91-F339 HydrophobicContact CG2-CD1 4.13Å; I91-C341 HydrophobicContact CD1-CB 4.37Å; I91-C341 HydrophobicContact CG1-CB 3.55Å; I91-I368 HydrophobicContact CD1-CG1 3.63Å; I91-M371 HydrophobicContact CB-CB 4.48Å; I91-M371 HydrophobicContact CB-CG 3.76Å; I91-M371 HydrophobicContact CD1-CG 4.2Å; I91-M371 HydrophobicContact CG2-CB 3.7Å; I91-M371 HydrophobicContact CG2-CG 3.52Å; I91-Y375 HydrophobicContact CG2-CE2 4.13Å; I91-Y375 PolarHBondContact O-OH 3.22Å
92	M	89.3	Confident	90.5	Very high	1 Å²	1	11.5 Å²	11.5	1%	0.005	6%	0.062	C	C	.	.	H	α-helix	trans	-47.1	-56.5	-172.8	171.6	146.4	-122.5	0	0	113.6	S88 I96 L233 M236 M371 M374 Y375	S88-M92 WeakPolarHBondContact O-CB 3.4Å; S88-M92 PolarHBondContact O-N 2.64Å; M92-I96 HydrophobicContact CE-CD1 3.56Å; M92-L233 HydrophobicContact SD-CD1 3.7Å; M92-M236 HydrophobicContact CE-CB 3.02Å; M92-M236 HydrophobicContact CE-CG 3.52Å; M92-M236 HydrophobicContact CE-SD 4.29Å; M92-M236 HydrophobicContact CG-CG 4.16Å; M92-M236 HydrophobicContact SD-CB 3.31Å; M92-M236 WeakPolarHBondContact SD-CB 3.28Å; M92-M236 HydrophobicContact SD-CG 3.38Å; M92-M236 WeakPolarHBondContact SD-CG 3.48Å; M92-M371 HydrophobicContact CB-SD 3.8Å; M92-M374 HydrophobicContact CE-CE 3.33Å; M92-M374 HydrophobicContact CE-SD 4.26Å; M92-M374 HydrophobicContact SD-CE 3.88Å; M92-Y375 VanDerWaalsContact C-OH 3.3Å; M92-Y375 WeakPolarHBondContact CA-OH 3.41Å; M92-Y375 PolarHBondContact N-OH 2.69Å; M92-Y375 PolarHBondContact O-OH 2.98Å
93	G	80.2	Confident	90.8	Very high	7 Å²	7	9.6 Å²	9.6	7%	0.072	5%	0.053	C	C	.	.	T	Hydrogen-bonded Turn	trans	29.6	-142.9	-178.6	0	0	0	0	0	117.1	N89 I91 G95 Y172	N89-G93 PolarHBondContact O-N 2.99Å; I91-G93 PolarHBondContact O-N 2.7Å; G93-G95 VanDerWaalsContact C-N 3.32Å; G93-Y172 WeakPolarHBondContact CA-OH 3.48Å
94	S	84.3	Confident	90.9	Very high	3 Å²	3	9.8 Å²	9.8	2%	0.021	6%	0.055	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.6	-10.4	176	60	0	0	0	0	112	I96 L97 S171 Y172 F474	S94-I96 PolarHBondContact O-N 2.9Å; S94-L97 PolarHBondContact O-N 3.42Å; S94-S171 WeakPolarHBondContact CB-OG 3.12Å; S94-S171 WeakPolarHBondContact OG-CB 3.32Å; S94-S171 PolarHBondContact OG-OG 3.41Å; S94-Y172 VanDerWaalsContact N-CE1 3.25Å; S94-F474 WeakPolarHBondContact O-CZ 3.17Å; S94-F474 VanDerWaalsContact OG-CE1 3.28Å; S94-F474 WeakPolarHBondContact OG-CE1 3.11Å
95	G	83.2	Confident	90.8	Very high	1 Å²	1	10 Å²	10	1%	0.01	6%	0.055	C	C	.	.	G	3₁₀ helix	trans	-59.4	-35.1	-173.8	0	0	0	0	0	112.2	G93 L97 G98 L99	G93-G95 VanDerWaalsContact C-N 3.32Å; G95-L97 PolarHBondContact O-N 3.33Å; G95-L97 VanDerWaalsContact O-N 3.17Å; G95-G98 PolarHBondContact O-N 3.03Å; G95-G98 VanDerWaalsContact O-N 3.1Å; G95-L99 WeakPolarHBondContact O-CG 3.38Å
96	I	90.3	Very high	90.9	Very high	0 Å²	0	5.6 Å²	5.6	0%	0	4%	0.036	C	C	.	.	G	3₁₀ helix	trans	-54.5	-35	179.4	-165.7	168.9	0	0	0	113.7	M92 S94 G98 L99 M236 F239 Y375	M92-I96 HydrophobicContact CE-CD1 3.56Å; S94-I96 PolarHBondContact O-N 2.9Å; I96-G98 VanDerWaalsContact C-N 3.31Å; I96-G98 PolarHBondContact O-N 3.36Å; I96-L99 PolarHBondContact O-N 3.24Å; I96-M236 HydrophobicContact CG2-SD 4.46Å; I96-F239 HydrophobicContact CD1-CD1 4.2Å; I96-F239 HydrophobicContact CD1-CE1 3.91Å; I96-F239 HydrophobicContact CG1-CE1 4.07Å; I96-F239 HydrophobicContact CG2-CE1 4.43Å; I96-Y375 HydrophobicContact CB-CD1 4.21Å; I96-Y375 HydrophobicContact CB-CE1 3.88Å; I96-Y375 HydrophobicContact CD1-CD1 4.3Å; I96-Y375 HydrophobicContact CD1-CE1 4.46Å; I96-Y375 HydrophobicContact CG1-CD1 4.05Å; I96-Y375 HydrophobicContact CG1-CE1 4.2Å
97	L	87.8	Confident	91.1	Very high	1 Å²	1	4.8 Å²	4.8	1%	0.005	3%	0.032	C	C	.	.	G	3₁₀ helix	trans	-73.3	-22.4	-176.7	-60.6	-173.7	0	0	0	113.4	S94 G95 I175 F239 L394 L395 V415	S94-L97 PolarHBondContact O-N 3.42Å; G95-L97 PolarHBondContact O-N 3.33Å; G95-L97 VanDerWaalsContact O-N 3.17Å; L97-I175 HydrophobicContact CD1-CD1 3.5Å; L97-I175 VanDerWaalsContact CD1-CD1 3.5Å; L97-I175 HydrophobicContact CD1-CG1 3.83Å; L97-I175 HydrophobicContact CD1-CG2 4.36Å; L97-F239 HydrophobicContact CD2-CE1 4.07Å; L97-F239 HydrophobicContact CD2-CE2 4.06Å; L97-F239 HydrophobicContact CD2-CZ 3.5Å; L97-F239 VanDerWaalsContact CD2-CZ 3.5Å; L97-L394 PolarHBondContact O-N 3.24Å; L97-L395 HydrophobicContact CD2-CD1 3.71Å; L97-V415 HydrophobicContact CD1-CG1 4.24Å
98	G	89.5	Confident	91.3	Very high	1 Å²	1	6.2 Å²	6.2	1%	0.01	4%	0.039	C	C	.	.	G	3₁₀ helix	trans	-94.7	-3.6	178.4	0	0	0	0	0	114.4	G95 I96 Y101 A102	G95-G98 PolarHBondContact O-N 3.03Å; G95-G98 VanDerWaalsContact O-N 3.1Å; I96-G98 VanDerWaalsContact C-N 3.31Å; I96-G98 PolarHBondContact O-N 3.36Å; G98-Y101 WeakPolarHBondContact O-CB 3.41Å; G98-A102 PolarHBondContact O-N 3.49Å; G98-A102 VanDerWaalsContact O-N 3.11Å
99	L	94.3	Very high	91.4	Very high	0 Å²	0	8.5 Å²	8.5	0%	0	5%	0.053	C	C	.	.	H	α-helix	trans	-75.4	-35.4	-173.6	-65.6	-179.2	0	0	0	113.7	G95 I96 Y101 A102 M103 F111 I334 L335 A338 Y375 A379	G95-L99 WeakPolarHBondContact O-CG 3.38Å; I96-L99 PolarHBondContact O-N 3.24Å; L99-Y101 VanDerWaalsContact C-N 3.28Å; L99-Y101 PolarHBondContact O-N 3.19Å; L99-A102 PolarHBondContact O-N 2.99Å; L99-M103 PolarHBondContact O-N 3.37Å; L99-F111 HydrophobicContact CB-CZ 4.14Å; L99-F111 HydrophobicContact CD2-CZ 4.31Å; L99-F111 WeakPolarHBondContact O-CE2 3.08Å; L99-I334 HydrophobicContact CD2-CG2 4.43Å; L99-L335 HydrophobicContact CD2-CD2 3.52Å; L99-A338 HydrophobicContact CD2-CB 4.27Å; L99-Y375 HydrophobicContact CD1-CD1 3.52Å; L99-Y375 HydrophobicContact CD1-CD2 3.86Å; L99-Y375 HydrophobicContact CD1-CE1 4.2Å; L99-Y375 HydrophobicContact CD1-CE2 4.49Å; L99-Y375 HydrophobicContact CD1-CG 3.3Å; L99-A379 HydrophobicContact CB-CB 3.87Å
100	S	95.1	Very high	91.6	Very high	0 Å²	0	9.8 Å²	9.8	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-64.4	-37.6	175.3	-51.9	0	0	0	0	111	M103 A104 S378 A379 G382	S100-M103 PolarHBondContact O-N 2.87Å; S100-A104 PolarHBondContact O-N 3.35Å; S100-S378 PolarHBondContact OG-O 2.74Å; S100-S378 VanDerWaalsContact OG-O 3.05Å; S100-A379 PolarHBondContact OG-O 3.24Å; S100-G382 WeakPolarHBondContact OG-CA 3.31Å
101	Y	94.3	Very high	91.9	Very high	21 Å²	21	8.3 Å²	8.3	8%	0.082	5%	0.047	C	C	.	.	H	α-helix	trans	-61.8	-46.7	172	174.6	-101.4	0	0	0	111.7	G98 L99 M103 A104 N105 Q327 I334 V390 E391 A392 R471	G98-Y101 WeakPolarHBondContact O-CB 3.41Å; L99-Y101 VanDerWaalsContact C-N 3.28Å; L99-Y101 PolarHBondContact O-N 3.19Å; Y101-M103 VanDerWaalsContact C-N 3.29Å; Y101-M103 PolarHBondContact O-N 2.93Å; Y101-A104 PolarHBondContact O-N 3.39Å; Y101-N105 WeakPolarHBondContact CD2-ND2 3.42Å; Y101-N105 WeakPolarHBondContact CE2-ND2 3.13Å; Y101-N105 VanDerWaalsContact CZ-ND2 3.26Å; Y101-N105 PolarHBondContact O-N 3.35Å; Y101-N105 VanDerWaalsContact O-N 3.16Å; Y101-N105 PolarHBondContact O-ND2 3.48Å; Y101-Q327 PolarHBondContact OH-OE1 2.92Å; Y101-I334 HydrophobicContact CD1-CD1 4.23Å; Y101-I334 HydrophobicContact CE1-CD1 4.43Å; Y101-V390 WeakPolarHBondContact CD2-O 3.49Å; Y101-E391 WeakPolarHBondContact CB-O 3.1Å; Y101-A392 HydrophobicContact CD2-CB 4.45Å; Y101-A392 HydrophobicContact CG-CB 4.39Å; Y101-R471 HydrophobicContact CE1-CG 4.06Å; Y101-R471 VanDerWaalsContact OH-CD 3.31Å; Y101-R471 WeakPolarHBondContact OH-CD 3.43Å; Y101-R471 PolarHBondContact OH-NH1 2.98Å
102	A	94.7	Very high	92.1	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-60.5	-38.3	176.4	0	0	0	0	0	112.2	G98 L99 N105 T106 F111 T331 I334	G98-A102 PolarHBondContact O-N 3.49Å; G98-A102 VanDerWaalsContact O-N 3.11Å; L99-A102 PolarHBondContact O-N 2.99Å; A102-N105 PolarHBondContact O-N 3.32Å; A102-T106 PolarHBondContact O-N 3.41Å; A102-T106 PolarHBondContact O-OG1 3.05Å; A102-F111 HydrophobicContact CB-CD2 4.18Å; A102-F111 HydrophobicContact CB-CE2 3.78Å; A102-T331 HydrophobicContact CB-CG2 3.98Å; A102-T331 PolarHBondContact O-OG1 3.18Å; A102-I334 HydrophobicContact CB-CG2 4.44Å
103	M	95.8	Very high	92.5	Very high	0 Å²	0	15 Å²	15	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-67.5	-42.8	174.7	-175.4	178.8	-74.5	0	0	112	L99 S100 Y101 N105 T106 G107 I108 F111 M376 A379 L380 Y383	L99-M103 PolarHBondContact O-N 3.37Å; S100-M103 PolarHBondContact O-N 2.87Å; Y101-M103 VanDerWaalsContact C-N 3.29Å; Y101-M103 PolarHBondContact O-N 2.93Å; M103-N105 PolarHBondContact O-N 2.97Å; M103-T106 PolarHBondContact O-N 3.49Å; M103-G107 WeakPolarHBondContact O-CA 3.4Å; M103-G107 PolarHBondContact O-N 2.67Å; M103-I108 HydrophobicContact SD-CG1 4.15Å; M103-F111 HydrophobicContact CB-CB 4.2Å; M103-F111 HydrophobicContact CB-CD1 4.17Å; M103-F111 HydrophobicContact CB-CD2 3.8Å; M103-F111 HydrophobicContact CB-CE2 4.19Å; M103-F111 HydrophobicContact CB-CG 3.77Å; M103-F111 HydrophobicContact CE-CB 4.41Å; M103-F111 HydrophobicContact CE-CD1 3.21Å; M103-F111 HydrophobicContact CE-CE1 3.57Å; M103-F111 HydrophobicContact CE-CG 3.94Å; M103-F111 HydrophobicContact CG-CB 4.03Å; M103-F111 HydrophobicContact CG-CD1 4.26Å; M103-F111 HydrophobicContact CG-CG 4.01Å; M103-M376 HydrophobicContact CE-CE 4.36Å; M103-A379 HydrophobicContact CB-CB 4.43Å; M103-A379 HydrophobicContact CE-CB 3.66Å; M103-A379 HydrophobicContact SD-CB 4.47Å; M103-L380 HydrophobicContact CE-CB 4.19Å; M103-L380 HydrophobicContact SD-CB 4.42Å; M103-L380 HydrophobicContact SD-CD1 4.24Å; M103-Y383 HydrophobicContact CG-CD1 4.12Å; M103-Y383 HydrophobicContact CG-CG 3.98Å; M103-Y383 HydrophobicContact SD-CD1 3.77Å; M103-Y383 HydrophobicContact SD-CG 3.9Å
104	A	93.3	Very high	93.2	Very high	5 Å²	5	16.4 Å²	16.4	4%	0.041	9%	0.089	C	C	.	.	H	α-helix	trans	-57.1	-36.3	176.6	0	0	0	0	0	112.4	S100 Y101 Y383 V390	S100-A104 PolarHBondContact O-N 3.35Å; Y101-A104 PolarHBondContact O-N 3.39Å; A104-Y383 HydrophobicContact CB-CD2 3.79Å; A104-Y383 HydrophobicContact CB-CE2 4.04Å; A104-V390 HydrophobicContact CB-CB 4.1Å; A104-V390 HydrophobicContact CB-CG2 4.23Å
105	N	92.2	Very high	93.8	Very high	19 Å²	19	16.2 Å²	16.2	10%	0.102	9%	0.088	C	C	.	.	T	Hydrogen-bonded Turn	trans	-89.7	-1.7	-177.8	-68.3	-70.7	0	0	0	115.2	Y101 A102 M103 N325 Q327 T328	Y101-N105 WeakPolarHBondContact CD2-ND2 3.42Å; Y101-N105 WeakPolarHBondContact CE2-ND2 3.13Å; Y101-N105 VanDerWaalsContact CZ-ND2 3.26Å; Y101-N105 PolarHBondContact O-N 3.35Å; Y101-N105 VanDerWaalsContact O-N 3.16Å; Y101-N105 PolarHBondContact O-ND2 3.48Å; A102-N105 PolarHBondContact O-N 3.32Å; M103-N105 PolarHBondContact O-N 2.97Å; N105-N325 PolarHBondContact OD1-ND2 3.36Å; N105-Q327 HydrophobicContact CB-CB 4.14Å; N105-Q327 WeakPolarHBondContact OD1-CB 3.33Å; N105-T328 PolarHBondContact O-OG1 2.98Å
106	T	94.1	Very high	94.5	Very high	0 Å²	0	18.9 Å²	18.9	0%	0	10%	0.104	C	C	.	.	T	Hydrogen-bonded Turn	trans	-126	-18.8	177.4	47.7	0	0	0	0	114	A102 M103 L110 F111 L114 V323 T328 T331	A102-T106 PolarHBondContact O-N 3.41Å; A102-T106 PolarHBondContact O-OG1 3.05Å; M103-T106 PolarHBondContact O-N 3.49Å; T106-L110 HydrophobicContact CG2-CD2 4.21Å; T106-L110 WeakPolarHBondContact O-CB 3.24Å; T106-F111 WeakPolarHBondContact OG1-CB 3.42Å; T106-L114 HydrophobicContact CG2-CD1 4.44Å; T106-V323 WeakPolarHBondContact CA-O 3.23Å; T106-V323 PolarHBondContact O-N 3.4Å; T106-T328 HydrophobicContact CG2-CG2 3.72Å; T106-T331 HydrophobicContact CG2-CG2 3.7Å; T106-T331 WeakPolarHBondContact CG2-OG1 3.4Å
107	G	94.6	Very high	94.8	Very high	0 Å²	0	20.8 Å²	20.8	0%	0	12%	0.12	C	C	.	.			trans	79.2	160.6	-169.7	0	0	0	0	0	112.4	M103 V109 F111 K320 Y321	M103-G107 WeakPolarHBondContact O-CA 3.4Å; M103-G107 PolarHBondContact O-N 2.67Å; G107-V109 PolarHBondContact O-N 2.91Å; G107-F111 WeakPolarHBondContact O-CB 3.31Å; G107-F111 PolarHBondContact O-N 3.47Å; G107-K320 CarbonylContact C-O 3.59Å; G107-K320 WeakPolarHBondContact CA-O 3.49Å; G107-Y321 CarbonylContact C-O 3.37Å
108	I	96.1	Very high	95.2	Very high	30 Å²	30	21.1 Å²	21.1	15%	0.154	12%	0.122	C	C	.	.	H	α-helix	trans	-60.2	-44.1	-169.9	-61.1	173.7	0	0	0	112.2	M103 T112 P319 K320 Y321 L380 Y383 L384	M103-I108 HydrophobicContact SD-CG1 4.15Å; I108-T112 WeakPolarHBondContact O-CB 3.41Å; I108-T112 PolarHBondContact O-N 3.09Å; I108-T112 PolarHBondContact O-OG1 3.09Å; I108-P319 HydrophobicContact CD1-CB 3.79Å; I108-K320 PolarHBondContact N-O 2.84Å; I108-Y321 PolarHBondContact N-O 3.03Å; I108-L380 HydrophobicContact CD1-CD1 4.21Å; I108-L380 HydrophobicContact CG1-CD1 4.47Å; I108-L380 HydrophobicContact CG2-CD1 4.33Å; I108-Y383 HydrophobicContact CD1-CD1 4.22Å; I108-Y383 HydrophobicContact CD1-CE1 3.88Å; I108-Y383 HydrophobicContact CG1-CD1 3.92Å; I108-Y383 HydrophobicContact CG1-CE1 3.68Å; I108-L384 HydrophobicContact CD1-CD2 4.43Å
109	V	96	Very high	95.6	Very high	50 Å²	50	21.2 Å²	21.2	30%	0.303	12%	0.122	S	C	.	.	H	α-helix	trans	-71.5	-51.4	-172.7	176.9	0	0	0	0	110.5	G107 F111 T112 I113 Y321 F322	G107-V109 PolarHBondContact O-N 2.91Å; V109-F111 VanDerWaalsContact C-N 3.35Å; V109-F111 PolarHBondContact O-N 2.89Å; V109-T112 PolarHBondContact O-N 2.97Å; V109-I113 HydrophobicContact CG1-CD1 3.92Å; V109-I113 WeakPolarHBondContact O-CG1 3.25Å; V109-I113 PolarHBondContact O-N 2.87Å; V109-Y321 HydrophobicContact CG2-CD1 3.85Å; V109-Y321 HydrophobicContact CG2-CG 4.37Å; V109-Y321 PolarHBondContact N-O 3.44Å; V109-Y321 VanDerWaalsContact N-O 3.09Å; V109-F322 HydrophobicContact CB-CE1 4.1Å; V109-F322 HydrophobicContact CB-CE2 4.26Å; V109-F322 HydrophobicContact CB-CZ 3.84Å; V109-F322 HydrophobicContact CG1-CE1 3.93Å; V109-F322 HydrophobicContact CG1-CE2 4.37Å; V109-F322 HydrophobicContact CG1-CZ 3.59Å; V109-F322 HydrophobicContact CG2-CE2 4.47Å; V109-F322 HydrophobicContact CG2-CZ 4.45Å
110	L	94.8	Very high	95.7	Very high	30 Å²	30	26.1 Å²	26.1	16%	0.157	15%	0.148	C	C	.	.	H	α-helix	trans	-62.9	-43.2	-179.9	-179.1	59.4	0	0	0	111	T106 T112 I113 L114 F322 F324	T106-L110 HydrophobicContact CG2-CD2 4.21Å; T106-L110 WeakPolarHBondContact O-CB 3.24Å; L110-T112 VanDerWaalsContact C-N 3.34Å; L110-T112 PolarHBondContact O-N 2.84Å; L110-I113 PolarHBondContact O-N 2.84Å; L110-L114 HydrophobicContact CD1-CD1 4.1Å; L110-L114 HydrophobicContact CD1-CG 4.11Å; L110-L114 HydrophobicContact CG-CD1 3.9Å; L110-L114 HydrophobicContact CG-CG 4.36Å; L110-L114 WeakPolarHBondContact O-CB 3.48Å; L110-L114 VanDerWaalsContact O-CG 3.25Å; L110-L114 WeakPolarHBondContact O-CG 3.42Å; L110-L114 PolarHBondContact O-N 3.47Å; L110-F322 HydrophobicContact CB-CD1 4.22Å; L110-F324 HydrophobicContact CD2-CD1 4.44Å; L110-F324 HydrophobicContact CD2-CE1 3.69Å; L110-F324 HydrophobicContact CD2-CZ 3.89Å
111	F	97	Very high	95.8	Very high	0 Å²	0	29 Å²	29	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-56.5	-47.8	174.5	-179.1	-92.1	0	0	0	112	L99 A102 M103 T106 G107 V109 I113 L114 L115 L335 M376 A379	L99-F111 HydrophobicContact CB-CZ 4.14Å; L99-F111 HydrophobicContact CD2-CZ 4.31Å; L99-F111 WeakPolarHBondContact O-CE2 3.08Å; A102-F111 HydrophobicContact CB-CD2 4.18Å; A102-F111 HydrophobicContact CB-CE2 3.78Å; M103-F111 HydrophobicContact CB-CB 4.2Å; M103-F111 HydrophobicContact CB-CD1 4.17Å; M103-F111 HydrophobicContact CB-CD2 3.8Å; M103-F111 HydrophobicContact CB-CE2 4.19Å; M103-F111 HydrophobicContact CB-CG 3.77Å; M103-F111 HydrophobicContact CE-CB 4.41Å; M103-F111 HydrophobicContact CE-CD1 3.21Å; M103-F111 HydrophobicContact CE-CE1 3.57Å; M103-F111 HydrophobicContact CE-CG 3.94Å; M103-F111 HydrophobicContact CG-CB 4.03Å; M103-F111 HydrophobicContact CG-CD1 4.26Å; M103-F111 HydrophobicContact CG-CG 4.01Å; T106-F111 WeakPolarHBondContact OG1-CB 3.42Å; G107-F111 WeakPolarHBondContact O-CB 3.31Å; G107-F111 PolarHBondContact O-N 3.47Å; V109-F111 VanDerWaalsContact C-N 3.35Å; V109-F111 PolarHBondContact O-N 2.89Å; F111-I113 PolarHBondContact O-N 2.96Å; F111-L114 PolarHBondContact O-N 3.21Å; F111-L115 HydrophobicContact CE1-CB 4.27Å; F111-L115 HydrophobicContact CE1-CD1 4.37Å; F111-L115 HydrophobicContact CE1-CD2 4.08Å; F111-L115 HydrophobicContact CE1-CG 4.48Å; F111-L115 HydrophobicContact CZ-CD1 4.06Å; F111-L115 HydrophobicContact CZ-CD2 4.49Å; F111-L115 WeakPolarHBondContact O-CB 3.33Å; F111-L115 PolarHBondContact O-N 3.5Å; F111-L335 HydrophobicContact CE2-CD2 3.84Å; F111-L335 HydrophobicContact CZ-CD2 4.18Å; F111-M376 HydrophobicContact CD1-SD 4.3Å; F111-M376 HydrophobicContact CE1-SD 4.06Å; F111-A379 HydrophobicContact CD1-CB 4.42Å; F111-A379 HydrophobicContact CE1-CB 3.49Å; F111-A379 VanDerWaalsContact CE1-CB 3.49Å; F111-A379 HydrophobicContact CZ-CB 3.55Å
112	T	97.6	Very high	95.9	Very high	47 Å²	47	28 Å²	28	29%	0.288	16%	0.159	S	C	.	.	H	α-helix	trans	-60.7	-45.4	-179.1	-56.7	0	0	0	0	111.2	I108 V109 L110 L115 V116 M376	I108-T112 WeakPolarHBondContact O-CB 3.41Å; I108-T112 PolarHBondContact O-N 3.09Å; I108-T112 PolarHBondContact O-OG1 3.09Å; V109-T112 PolarHBondContact O-N 2.97Å; L110-T112 VanDerWaalsContact C-N 3.34Å; L110-T112 PolarHBondContact O-N 2.84Å; T112-L115 PolarHBondContact O-N 3.36Å; T112-V116 WeakPolarHBondContact O-CB 3.46Å; T112-V116 WeakPolarHBondContact O-CG2 3.3Å; T112-V116 PolarHBondContact O-N 3.26Å; T112-M376 HydrophobicContact CG2-CE 3.83Å; T112-M376 HydrophobicContact CG2-SD 4.23Å; T112-M376 VanDerWaalsContact OG1-CE 3.28Å; T112-M376 WeakPolarHBondContact OG1-CE 3.46Å
113	I	96.9	Very high	95.9	Very high	100 Å²	100	30 Å²	30	51%	0.513	17%	0.169	S	C	.	.	H	α-helix	trans	-60.8	-47.7	177.3	-68.2	168.6	0	0	0	110.4	V109 L110 F111 A117	V109-I113 HydrophobicContact CG1-CD1 3.92Å; V109-I113 WeakPolarHBondContact O-CG1 3.25Å; V109-I113 PolarHBondContact O-N 2.87Å; L110-I113 PolarHBondContact O-N 2.84Å; F111-I113 PolarHBondContact O-N 2.96Å; I113-A117 VanDerWaalsContact O-CB 3.22Å; I113-A117 WeakPolarHBondContact O-CB 3.32Å; I113-A117 PolarHBondContact O-N 3.44Å
114	L	95.7	Very high	96	Very high	36 Å²	36	33.1 Å²	33.1	19%	0.188	18%	0.181	C	C	.	.	H	α-helix	trans	-63.9	-42.8	-179.8	-69.8	172.9	0	0	0	111.9	T106 L110 F111 A117 V118 T331 V332 L335	T106-L114 HydrophobicContact CG2-CD1 4.44Å; L110-L114 HydrophobicContact CD1-CD1 4.1Å; L110-L114 HydrophobicContact CD1-CG 4.11Å; L110-L114 HydrophobicContact CG-CD1 3.9Å; L110-L114 HydrophobicContact CG-CG 4.36Å; L110-L114 WeakPolarHBondContact O-CB 3.48Å; L110-L114 VanDerWaalsContact O-CG 3.25Å; L110-L114 WeakPolarHBondContact O-CG 3.42Å; L110-L114 PolarHBondContact O-N 3.47Å; F111-L114 PolarHBondContact O-N 3.21Å; L114-A117 PolarHBondContact O-N 3.05Å; L114-V118 WeakPolarHBondContact O-CG2 3.21Å; L114-V118 PolarHBondContact O-N 3.03Å; L114-T331 HydrophobicContact CD1-CG2 4.14Å; L114-V332 HydrophobicContact CD1-CG2 4.22Å; L114-V332 HydrophobicContact CD2-CG2 4.2Å; L114-L335 HydrophobicContact CB-CD1 3.63Å
115	L	97.1	Very high	96.2	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-63.4	-47.3	179.7	-165.7	80.7	0	0	0	111.4	F111 T112 V118 A119 L335 F339 L372 M376	F111-L115 HydrophobicContact CE1-CB 4.27Å; F111-L115 HydrophobicContact CE1-CD1 4.37Å; F111-L115 HydrophobicContact CE1-CD2 4.08Å; F111-L115 HydrophobicContact CE1-CG 4.48Å; F111-L115 HydrophobicContact CZ-CD1 4.06Å; F111-L115 HydrophobicContact CZ-CD2 4.49Å; F111-L115 WeakPolarHBondContact O-CB 3.33Å; F111-L115 PolarHBondContact O-N 3.5Å; T112-L115 PolarHBondContact O-N 3.36Å; L115-V118 PolarHBondContact O-N 2.89Å; L115-A119 WeakPolarHBondContact O-CB 3.09Å; L115-A119 PolarHBondContact O-N 3.43Å; L115-L335 HydrophobicContact CD1-CD1 4.41Å; L115-L335 HydrophobicContact CD1-CD2 3.45Å; L115-L335 VanDerWaalsContact CD1-CD2 3.45Å; L115-L335 HydrophobicContact CD1-CG 4.42Å; L115-F339 HydrophobicContact CD1-CE2 3.51Å; L115-F339 HydrophobicContact CD1-CZ 4.16Å; L115-F339 HydrophobicContact CG-CE2 3.87Å; L115-F339 HydrophobicContact CG-CZ 4.22Å; L115-L372 HydrophobicContact CD2-CD1 3.61Å; L115-L372 HydrophobicContact CG-CD1 3.78Å; L115-M376 HydrophobicContact CB-SD 4.17Å; L115-M376 HydrophobicContact CD2-CB 4.42Å; L115-M376 HydrophobicContact CD2-CG 3.49Å; L115-M376 VanDerWaalsContact CD2-CG 3.49Å; L115-M376 HydrophobicContact CD2-SD 3.18Å; L115-M376 WeakPolarHBondContact CD2-SD 3.32Å; L115-M376 HydrophobicContact CG-SD 4.26Å
116	V	98.1	Very high	96.4	Very high	57 Å²	57	32 Å²	32	35%	0.345	18%	0.175	S	C	.	.	H	α-helix	trans	-64	-42.3	176.9	172.8	0	0	0	0	110.8	T112 A119 I120 L372	T112-V116 WeakPolarHBondContact O-CB 3.46Å; T112-V116 WeakPolarHBondContact O-CG2 3.3Å; T112-V116 PolarHBondContact O-N 3.26Å; V116-A119 PolarHBondContact O-N 3.17Å; V116-I120 HydrophobicContact CG1-CD1 3.78Å; V116-I120 HydrophobicContact CG1-CG1 4.42Å; V116-I120 VanDerWaalsContact O-CG1 3.31Å; V116-I120 WeakPolarHBondContact O-CG1 3.37Å; V116-I120 PolarHBondContact O-N 3.22Å; V116-L372 HydrophobicContact CG2-CD1 4.39Å
117	A	96.6	Very high	96.5	Very high	39 Å²	39	34.7 Å²	34.7	32%	0.322	19%	0.187	S	C	.	.	H	α-helix	trans	-60.1	-51.2	177.4	0	0	0	0	0	111.6	I113 L114 A119 I120 L121	I113-A117 VanDerWaalsContact O-CB 3.22Å; I113-A117 WeakPolarHBondContact O-CB 3.32Å; I113-A117 PolarHBondContact O-N 3.44Å; L114-A117 PolarHBondContact O-N 3.05Å; A117-A119 VanDerWaalsContact C-N 3.31Å; A117-A119 PolarHBondContact O-N 3.01Å; A117-I120 PolarHBondContact O-N 3.42Å; A117-L121 WeakPolarHBondContact O-CB 3.27Å; A117-L121 WeakPolarHBondContact O-CD1 3.38Å; A117-L121 WeakPolarHBondContact O-CG 3.33Å; A117-L121 PolarHBondContact O-N 3.43Å
118	V	96.1	Very high	96.5	Very high	8 Å²	8	34.8 Å²	34.8	5%	0.048	19%	0.188	C	C	.	.	H	α-helix	trans	-62.8	-37.4	179	175.7	0	0	0	0	111.5	L114 L115 L121 S122 L335 F339	L114-V118 WeakPolarHBondContact O-CG2 3.21Å; L114-V118 PolarHBondContact O-N 3.03Å; L115-V118 PolarHBondContact O-N 2.89Å; V118-L121 PolarHBondContact O-N 2.94Å; V118-S122 VanDerWaalsContact O-CB 3.31Å; V118-S122 WeakPolarHBondContact O-CB 3.48Å; V118-S122 PolarHBondContact O-N 2.9Å; V118-L335 HydrophobicContact CB-CB 4.46Å; V118-L335 HydrophobicContact CG1-CB 4.44Å; V118-L335 HydrophobicContact CG2-CB 4.15Å; V118-F339 HydrophobicContact CB-CD2 4.3Å; V118-F339 HydrophobicContact CG1-CB 4Å; V118-F339 HydrophobicContact CG1-CD2 3.76Å; V118-F339 HydrophobicContact CG1-CG 4.26Å
119	A	96.9	Very high	96.5	Very high	3 Å²	3	33.4 Å²	33.4	3%	0.025	18%	0.181	C	C	.	.	H	α-helix	trans	-63	-44.4	175.2	0	0	0	0	0	112.6	L115 V116 A117 S122 L123 F339 I368 L372	L115-A119 WeakPolarHBondContact O-CB 3.09Å; L115-A119 PolarHBondContact O-N 3.43Å; V116-A119 PolarHBondContact O-N 3.17Å; A117-A119 VanDerWaalsContact C-N 3.31Å; A117-A119 PolarHBondContact O-N 3.01Å; A119-S122 PolarHBondContact O-N 3.35Å; A119-L123 WeakPolarHBondContact O-CG 3.38Å; A119-L123 PolarHBondContact O-N 2.91Å; A119-F339 HydrophobicContact CB-CD1 4.47Å; A119-F339 HydrophobicContact CB-CE1 3.95Å; A119-F339 HydrophobicContact CB-CE2 4.19Å; A119-F339 HydrophobicContact CB-CZ 3.79Å; A119-I368 HydrophobicContact CB-CG2 4.08Å; A119-L372 HydrophobicContact CB-CD1 4.03Å; A119-L372 HydrophobicContact CB-CD2 4.47Å
120	I	97.1	Very high	96.4	Very high	104 Å²	104	31.1 Å²	31.1	53%	0.533	17%	0.167	S	C	.	.	H	α-helix	trans	-63.9	-44.3	176.1	-68.4	168.1	0	0	0	110.8	V116 A117 S122 L123 Y124	V116-I120 HydrophobicContact CG1-CD1 3.78Å; V116-I120 HydrophobicContact CG1-CG1 4.42Å; V116-I120 VanDerWaalsContact O-CG1 3.31Å; V116-I120 WeakPolarHBondContact O-CG1 3.37Å; V116-I120 PolarHBondContact O-N 3.22Å; A117-I120 PolarHBondContact O-N 3.42Å; I120-S122 VanDerWaalsContact C-N 3.33Å; I120-S122 PolarHBondContact O-N 3.15Å; I120-L123 WeakPolarHBondContact O-CB 3.43Å; I120-L123 PolarHBondContact O-N 2.89Å; I120-Y124 PolarHBondContact O-N 3.44Å
121	L	96.1	Very high	96.3	Very high	59 Å²	59	31.6 Å²	31.6	31%	0.309	17%	0.169	S	C	.	.	H	α-helix	trans	-64	-39.8	179.1	-66.8	164	0	0	0	111.1	A117 V118 Y124 S125 F487 F514	A117-L121 WeakPolarHBondContact O-CB 3.27Å; A117-L121 WeakPolarHBondContact O-CD1 3.38Å; A117-L121 WeakPolarHBondContact O-CG 3.33Å; A117-L121 PolarHBondContact O-N 3.43Å; V118-L121 PolarHBondContact O-N 2.94Å; L121-Y124 PolarHBondContact O-N 3.44Å; L121-S125 WeakPolarHBondContact O-CB 3.33Å; L121-S125 PolarHBondContact O-N 3.36Å; L121-F487 HydrophobicContact CB-CE1 4Å; L121-F487 HydrophobicContact CB-CZ 4.4Å; L121-F487 HydrophobicContact CD1-CE1 3.96Å; L121-F487 HydrophobicContact CD1-CZ 4.33Å; L121-F487 HydrophobicContact CG-CE1 4.37Å; L121-F514 HydrophobicContact CB-CE2 3.93Å; L121-F514 HydrophobicContact CB-CZ 4.42Å; L121-F514 HydrophobicContact CD2-CD2 3.94Å; L121-F514 HydrophobicContact CD2-CE2 3.56Å; L121-F514 HydrophobicContact CG-CE2 4.27Å
122	S	96.4	Very high	96.1	Very high	0 Å²	0	31.6 Å²	31.6	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-63.3	-44.1	173.4	-171.5	0	0	0	0	111.8	V118 A119 I120 Y124 S125 V126 F339 H342	V118-S122 VanDerWaalsContact O-CB 3.31Å; V118-S122 WeakPolarHBondContact O-CB 3.48Å; V118-S122 PolarHBondContact O-N 2.9Å; A119-S122 PolarHBondContact O-N 3.35Å; I120-S122 VanDerWaalsContact C-N 3.33Å; I120-S122 PolarHBondContact O-N 3.15Å; S122-Y124 PolarHBondContact O-N 3.43Å; S122-S125 WeakPolarHBondContact O-CB 3.21Å; S122-S125 PolarHBondContact O-N 2.94Å; S122-V126 WeakPolarHBondContact O-CG2 3.49Å; S122-V126 PolarHBondContact O-N 3.39Å; S122-F339 PolarHBondContact OG-O 3.2Å; S122-H342 PolarHBondContact OG-CE1 3.35Å
123	L	96.4	Very high	95.7	Very high	43 Å²	43	29.5 Å²	29.5	23%	0.225	16%	0.156	C	C	.	.	H	α-helix	trans	-60.1	-44.8	175.4	-78.7	166.5	0	0	0	113.1	A119 I120 S125 V126 H127 N365 I368	A119-L123 WeakPolarHBondContact O-CG 3.38Å; A119-L123 PolarHBondContact O-N 2.91Å; I120-L123 WeakPolarHBondContact O-CB 3.43Å; I120-L123 PolarHBondContact O-N 2.89Å; L123-S125 VanDerWaalsContact C-N 3.34Å; L123-V126 PolarHBondContact O-N 3.19Å; L123-H127 PolarHBondContact O-N 3.42Å; L123-H127 VanDerWaalsContact O-N 3.08Å; L123-N365 HydrophobicContact CD2-CB 4.39Å; L123-N365 VanDerWaalsContact CD2-OD1 3.32Å; L123-N365 WeakPolarHBondContact CD2-OD1 3.48Å; L123-I368 HydrophobicContact CD1-CG2 4.09Å; L123-I368 HydrophobicContact CD2-CB 4.05Å; L123-I368 HydrophobicContact CD2-CD1 3.53Å; L123-I368 HydrophobicContact CD2-CG1 4.29Å; L123-I368 HydrophobicContact CD2-CG2 4.34Å; L123-I368 HydrophobicContact CG-CB 4.22Å; L123-I368 HydrophobicContact CG-CD1 3.74Å; L123-I368 HydrophobicContact CG-CG2 3.96Å
124	Y	96.9	Very high	95.4	Very high	65 Å²	65	29.8 Å²	29.8	26%	0.255	15%	0.154	S	C	.	.	H	α-helix	trans	-62.6	-42.7	176.7	176.4	-110.3	0	0	0	111.5	I120 L121 S122 H127 L128 S510 A511 F514	I120-Y124 PolarHBondContact O-N 3.44Å; L121-Y124 PolarHBondContact O-N 3.44Å; S122-Y124 PolarHBondContact O-N 3.43Å; Y124-H127 WeakPolarHBondContact O-CB 3.19Å; Y124-H127 PolarHBondContact O-N 2.9Å; Y124-L128 HydrophobicContact CD1-CD1 4.12Å; Y124-L128 HydrophobicContact CD1-CG 4.46Å; Y124-L128 HydrophobicContact CE1-CD1 3.56Å; Y124-L128 HydrophobicContact CE1-CD2 4.46Å; Y124-L128 HydrophobicContact CE1-CG 4.08Å; Y124-L128 HydrophobicContact CE2-CD2 4.27Å; Y124-L128 HydrophobicContact CE2-CG 4.44Å; Y124-L128 WeakPolarHBondContact O-CG 3.43Å; Y124-L128 PolarHBondContact O-N 2.95Å; Y124-S510 PolarHBondContact OH-OG 3.05Å; Y124-S510 VanDerWaalsContact OH-OG 3.06Å; Y124-A511 PolarHBondContact OH-N 3.47Å; Y124-F514 AromaticContact CD1-CD1 3.96Å; Y124-F514 HydrophobicContact CD1-CD1 3.96Å; Y124-F514 HydrophobicContact CD1-CD2 4.24Å; Y124-F514 HydrophobicContact CD1-CE1 4.09Å; Y124-F514 HydrophobicContact CD1-CE2 4.35Å; Y124-F514 HydrophobicContact CD1-CG 4.06Å; Y124-F514 HydrophobicContact CD1-CZ 4.28Å; Y124-F514 HydrophobicContact CE1-CB 4.08Å; Y124-F514 AromaticContact CE1-CD1 3.86Å; Y124-F514 HydrophobicContact CE1-CD1 3.86Å; Y124-F514 HydrophobicContact CE1-CD2 4.44Å; Y124-F514 HydrophobicContact CE1-CE1 4.42Å; Y124-F514 AromaticContact CE1-CG 3.89Å; Y124-F514 HydrophobicContact CE1-CG 3.89Å
125	S	97.3	Very high	95	Very high	0 Å²	0	32.5 Å²	32.5	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-61.4	-45.4	175.9	172.1	0	0	0	0	113	L121 S122 L123 H127 L128 L129 H342 I486 P490	L121-S125 WeakPolarHBondContact O-CB 3.33Å; L121-S125 PolarHBondContact O-N 3.36Å; S122-S125 WeakPolarHBondContact O-CB 3.21Å; S122-S125 PolarHBondContact O-N 2.94Å; L123-S125 VanDerWaalsContact C-N 3.34Å; S125-H127 PolarHBondContact O-N 3.06Å; S125-L128 WeakPolarHBondContact O-CB 3.25Å; S125-L128 PolarHBondContact O-N 3.43Å; S125-L128 VanDerWaalsContact O-N 3.1Å; S125-L129 PolarHBondContact O-N 2.98Å; S125-H342 WeakPolarHBondContact CB-NE2 3.41Å; S125-H342 PolarHBondContact OG-CD2 3.39Å; S125-H342 PolarHBondContact OG-NE2 3.15Å; S125-I486 WeakPolarHBondContact CB-O 3.42Å; S125-I486 PolarHBondContact OG-O 3.31Å; S125-P490 VanDerWaalsContact OG-CG 3.27Å; S125-P490 WeakPolarHBondContact OG-CG 3.47Å
126	V	96.9	Very high	94.5	Very high	0 Å²	0	33 Å²	33	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-57.7	-40.9	174.3	170.4	0	0	0	0	110.9	S122 L123 L129 L130 V345	S122-V126 WeakPolarHBondContact O-CG2 3.49Å; S122-V126 PolarHBondContact O-N 3.39Å; L123-V126 PolarHBondContact O-N 3.19Å; V126-L129 PolarHBondContact O-N 3.44Å; V126-L130 HydrophobicContact CG1-CD1 4.07Å; V126-L130 HydrophobicContact CG1-CG 4.36Å; V126-L130 WeakPolarHBondContact O-CG 3.4Å; V126-L130 PolarHBondContact O-N 3.47Å; V126-V345 HydrophobicContact CG1-CG1 4.12Å; V126-V345 HydrophobicContact CG1-CG2 4.35Å; V126-V345 HydrophobicContact CG2-CG2 4.11Å
127	H	95.6	Very high	93.9	Very high	57 Å²	57	32.6 Å²	32.6	26%	0.264	18%	0.178	S	C	.	.	H	α-helix	trans	-61.5	-44.4	175.1	174.9	-91.4	0	0	0	112.4	L123 Y124 S125 L129 L130 M131	L123-H127 PolarHBondContact O-N 3.42Å; L123-H127 VanDerWaalsContact O-N 3.08Å; Y124-H127 WeakPolarHBondContact O-CB 3.19Å; Y124-H127 PolarHBondContact O-N 2.9Å; S125-H127 PolarHBondContact O-N 3.06Å; H127-L129 VanDerWaalsContact C-N 3.33Å; H127-L129 PolarHBondContact O-N 3.35Å; H127-L130 PolarHBondContact O-N 3.41Å; H127-M131 WeakPolarHBondContact O-CG 3.29Å; H127-M131 PolarHBondContact O-N 3.32Å
128	L	95.6	Very high	93.5	Very high	3 Å²	3	30.8 Å²	30.8	2%	0.016	16%	0.163	C	C	.	.	H	α-helix	trans	-61.5	-41	174.6	-65.3	-177.4	0	0	0	111.9	Y124 S125 M131 T132 P490 A491 Y494 A511 F514	Y124-L128 HydrophobicContact CD1-CD1 4.12Å; Y124-L128 HydrophobicContact CD1-CG 4.46Å; Y124-L128 HydrophobicContact CE1-CD1 3.56Å; Y124-L128 HydrophobicContact CE1-CD2 4.46Å; Y124-L128 HydrophobicContact CE1-CG 4.08Å; Y124-L128 HydrophobicContact CE2-CD2 4.27Å; Y124-L128 HydrophobicContact CE2-CG 4.44Å; Y124-L128 WeakPolarHBondContact O-CG 3.43Å; Y124-L128 PolarHBondContact O-N 2.95Å; S125-L128 WeakPolarHBondContact O-CB 3.25Å; S125-L128 PolarHBondContact O-N 3.43Å; S125-L128 VanDerWaalsContact O-N 3.1Å; L128-M131 PolarHBondContact O-N 2.74Å; L128-T132 WeakPolarHBondContact O-CG2 3.39Å; L128-T132 PolarHBondContact O-N 2.91Å; L128-T132 PolarHBondContact O-OG1 2.77Å; L128-P490 HydrophobicContact CB-CB 4.29Å; L128-A491 HydrophobicContact CD1-CB 4.39Å; L128-Y494 HydrophobicContact CB-CD2 4.46Å; L128-Y494 HydrophobicContact CD2-CD1 3.99Å; L128-Y494 HydrophobicContact CD2-CD2 3.68Å; L128-Y494 HydrophobicContact CD2-CE1 4.24Å; L128-Y494 HydrophobicContact CD2-CE2 3.96Å; L128-Y494 HydrophobicContact CD2-CG 3.71Å; L128-A511 HydrophobicContact CD1-CB 4.34Å; L128-F514 HydrophobicContact CD1-CD1 4.14Å; L128-F514 HydrophobicContact CD1-CE1 4.5Å
129	L	95.3	Very high	93	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-64.1	-43.3	177.9	-175.1	63.3	0	0	0	112	S125 V126 H127 T132 A133 Y141 L144 H342 V345 L346 P490	S125-L129 PolarHBondContact O-N 2.98Å; V126-L129 PolarHBondContact O-N 3.44Å; H127-L129 VanDerWaalsContact C-N 3.33Å; H127-L129 PolarHBondContact O-N 3.35Å; L129-T132 VanDerWaalsContact C-OG1 3.31Å; L129-T132 VanDerWaalsContact CA-OG1 3.26Å; L129-T132 WeakPolarHBondContact CA-OG1 3.11Å; L129-T132 PolarHBondContact O-N 3.49Å; L129-T132 PolarHBondContact O-OG1 3.1Å; L129-A133 WeakPolarHBondContact O-CB 3.43Å; L129-A133 PolarHBondContact O-N 2.94Å; L129-Y141 HydrophobicContact CD1-CD2 4Å; L129-Y141 HydrophobicContact CD1-CE2 3.53Å; L129-Y141 HydrophobicContact CD2-CD2 4.14Å; L129-Y141 HydrophobicContact CD2-CE2 3.62Å; L129-Y141 HydrophobicContact CG-CE2 4.23Å; L129-L144 HydrophobicContact CD1-CD2 4.07Å; L129-H342 HydrophobicContact CD2-CB 4.34Å; L129-V345 HydrophobicContact CD2-CB 4.32Å; L129-V345 HydrophobicContact CD2-CG1 4.36Å; L129-L346 HydrophobicContact CD1-CD1 4.28Å; L129-L346 HydrophobicContact CD2-CG 4.26Å; L129-L346 HydrophobicContact CG-CD1 4.48Å; L129-L346 HydrophobicContact CG-CD2 4.22Å; L129-L346 HydrophobicContact CG-CG 4.34Å; L129-P490 HydrophobicContact CB-CB 4.48Å
130	L	94.1	Very high	92.5	Very high	2 Å²	2	35.7 Å²	35.7	1%	0.01	19%	0.188	C	C	.	.	H	α-helix	trans	-68.3	-35	177.6	-69.4	175.7	0	0	0	112.3	V126 H127 K134 V345 L346 Y349 R357 M360 Q361	V126-L130 HydrophobicContact CG1-CD1 4.07Å; V126-L130 HydrophobicContact CG1-CG 4.36Å; V126-L130 WeakPolarHBondContact O-CG 3.4Å; V126-L130 PolarHBondContact O-N 3.47Å; H127-L130 PolarHBondContact O-N 3.41Å; L130-K134 PolarHBondContact O-N 2.86Å; L130-V345 HydrophobicContact CD2-CG1 3.93Å; L130-V345 HydrophobicContact CG-CG1 4.36Å; L130-L346 HydrophobicContact CD2-CD2 4.43Å; L130-Y349 HydrophobicContact CD2-CD1 4.05Å; L130-Y349 HydrophobicContact CD2-CG 4.33Å; L130-R357 HydrophobicContact CB-CG 4.06Å; L130-M360 HydrophobicContact CD1-CB 4.18Å; L130-M360 HydrophobicContact CD1-CG 4Å; L130-M360 HydrophobicContact CD2-CB 4.43Å; L130-M360 HydrophobicContact CD2-CG 3.9Å; L130-Q361 HydrophobicContact CD1-CB 4.49Å
131	M	92	Very high	92.1	Very high	40 Å²	40	31.1 Å²	31.1	20%	0.197	16%	0.163	C	C	.	.	H	α-helix	trans	-65.9	-44	173.1	-78.8	-64.9	-169.6	0	0	112.3	H127 L128 A133 K134 E135 R357 Y494	H127-M131 WeakPolarHBondContact O-CG 3.29Å; H127-M131 PolarHBondContact O-N 3.32Å; L128-M131 PolarHBondContact O-N 2.74Å; M131-A133 VanDerWaalsContact C-N 3.35Å; M131-K134 PolarHBondContact O-N 3.09Å; M131-E135 PolarHBondContact O-N 3.48Å; M131-E135 VanDerWaalsContact O-N 3.13Å; M131-R357 PolarHBondContact SD-NH1 2.85Å; M131-R357 VanDerWaalsContact SD-NH1 3.37Å; M131-Y494 HydrophobicContact CB-CD2 4.15Å; M131-Y494 HydrophobicContact CB-CE2 4.04Å
132	T	92.8	Very high	91.9	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-66.5	-37	177.6	45.3	0	0	0	0	112.3	L128 L129 K134 G136 L144 F493 Y494 V498	L128-T132 WeakPolarHBondContact O-CG2 3.39Å; L128-T132 PolarHBondContact O-N 2.91Å; L128-T132 PolarHBondContact O-OG1 2.77Å; L129-T132 VanDerWaalsContact C-OG1 3.31Å; L129-T132 VanDerWaalsContact CA-OG1 3.26Å; L129-T132 WeakPolarHBondContact CA-OG1 3.11Å; L129-T132 PolarHBondContact O-N 3.49Å; L129-T132 PolarHBondContact O-OG1 3.1Å; T132-K134 VanDerWaalsContact C-N 3.3Å; T132-K134 PolarHBondContact O-N 2.85Å; T132-G136 VanDerWaalsContact O-CA 3.32Å; T132-G136 WeakPolarHBondContact O-CA 3.4Å; T132-G136 PolarHBondContact O-N 2.84Å; T132-L144 WeakPolarHBondContact O-CD1 3.23Å; T132-F493 VanDerWaalsContact CG2-C 3.46Å; T132-F493 HydrophobicContact CG2-CB 3.95Å; T132-Y494 HydrophobicContact CG2-CD2 4.2Å; T132-Y494 HydrophobicContact CG2-CG 4.42Å; T132-V498 HydrophobicContact CG2-CG2 4.23Å
133	A	90.9	Very high	91.5	Very high	4 Å²	4	32 Å²	32	3%	0.033	17%	0.169	C	C	.	.	H	α-helix	trans	-61.7	-37.9	174.7	0	0	0	0	0	112.5	L129 M131 G137 S138 L139 L346	L129-A133 WeakPolarHBondContact O-CB 3.43Å; L129-A133 PolarHBondContact O-N 2.94Å; M131-A133 VanDerWaalsContact C-N 3.35Å; A133-G137 WeakPolarHBondContact O-CA 3.41Å; A133-G137 PolarHBondContact O-N 3.46Å; A133-S138 PolarHBondContact O-N 2.99Å; A133-L139 HydrophobicContact CB-CD2 4.18Å; A133-L346 HydrophobicContact CB-CD2 3.73Å
134	K	89.3	Confident	91.3	Very high	106 Å²	106	29.9 Å²	29.9	46%	0.461	16%	0.158	S	C	.	.	H	α-helix	trans	-64.6	-56.3	175.4	-176.5	-176.5	177.8	-176.6	0	111.5	L130 M131 T132 G137	L130-K134 PolarHBondContact O-N 2.86Å; M131-K134 PolarHBondContact O-N 3.09Å; T132-K134 VanDerWaalsContact C-N 3.3Å; T132-K134 PolarHBondContact O-N 2.85Å; K134-G137 PolarHBondContact O-N 3.45Å
135	E	87.9	Confident	91.2	Very high	93 Å²	93	26.8 Å²	26.8	44%	0.435	15%	0.146	S	C	.	.	H	α-helix	trans	-69.6	-34.6	-177.4	-65.8	-62.6	144	0	0	112.4	M131 G137 V498	M131-E135 PolarHBondContact O-N 3.48Å; M131-E135 VanDerWaalsContact O-N 3.13Å; E135-G137 VanDerWaalsContact C-N 3.29Å; E135-V498 HydrophobicContact CB-CG2 4.34Å; E135-V498 HydrophobicContact CG-CG1 4.4Å; E135-V498 HydrophobicContact CG-CG2 4.07Å
136	G	85.8	Confident	91	Very high	10 Å²	10	31.5 Å²	31.5	10%	0.103	17%	0.168	C	C	.	.	H	α-helix	trans	-74.6	-18.1	175.4	0	0	0	0	0	113.2	T132 S138 K147	T132-G136 VanDerWaalsContact O-CA 3.32Å; T132-G136 WeakPolarHBondContact O-CA 3.4Å; T132-G136 PolarHBondContact O-N 2.84Å; G136-S138 VanDerWaalsContact C-N 3.35Å; G136-S138 PolarHBondContact O-N 3.32Å; G136-K147 WeakPolarHBondContact O-CD 3.46Å; G136-K147 WeakPolarHBondContact O-CE 3.19Å; G136-K147 PolarHBondContact O-NZ 3.45Å
137	G	86.8	Confident	90.8	Very high	48 Å²	48	36.2 Å²	36.2	50%	0.495	19%	0.188	S	C	.	.	T	Hydrogen-bonded Turn	trans	56.1	45.3	-179.5	0	0	0	0	0	112.8	A133 K134 E135 K147	A133-G137 WeakPolarHBondContact O-CA 3.41Å; A133-G137 PolarHBondContact O-N 3.46Å; K134-G137 PolarHBondContact O-N 3.45Å; E135-G137 VanDerWaalsContact C-N 3.29Å; G137-K147 PolarHBondContact O-NZ 2.94Å
138	S	86.9	Confident	90.7	Very high	2 Å²	2	33.8 Å²	33.8	1%	0.014	18%	0.179	C	C	.	.			trans	-154.4	142	170.9	-169.4	0	0	0	0	110.3	E71 A133 G136 I140 T143	E71-S138 PolarHBondContact OE1-OG 3.43Å; A133-S138 PolarHBondContact O-N 2.99Å; G136-S138 VanDerWaalsContact C-N 3.35Å; G136-S138 PolarHBondContact O-N 3.32Å; S138-I140 PolarHBondContact OG-N 3.45Å; S138-T143 WeakPolarHBondContact OG-CB 3.21Å; S138-T143 WeakPolarHBondContact OG-CG2 3.37Å
139	L	85.6	Confident	90.7	Very high	30 Å²	30	38 Å²	38	16%	0.157	20%	0.197	C	C	.	.	S	Bend	trans	-100.3	18.8	176.4	-60.5	-177.5	0	0	0	112.5	A133 L346 Y349 R355	A133-L139 HydrophobicContact CB-CD2 4.18Å; L139-L346 VanDerWaalsContact O-CB 3.25Å; L139-L346 WeakPolarHBondContact O-CB 3.35Å; L139-Y349 HydrophobicContact CD1-CD1 4.43Å; L139-Y349 HydrophobicContact CD2-CD1 3.54Å; L139-Y349 HydrophobicContact CD2-CE1 3.75Å; L139-R355 VanDerWaalsContact CD1-NH1 3.26Å
140	I	87.2	Confident	90.7	Very high	84 Å²	84	39.2 Å²	39.2	43%	0.431	21%	0.209	S	C	.	.			trans	-115.5	122.1	177.9	-58.3	171.2	0	0	0	108.2	S138 E142 T143 L144	S138-I140 PolarHBondContact OG-N 3.45Å; I140-E142 VanDerWaalsContact C-N 3.34Å; I140-E142 VanDerWaalsContact CG2-OE2 3.28Å; I140-E142 WeakPolarHBondContact CG2-OE2 3.27Å; I140-E142 PolarHBondContact O-N 3.37Å; I140-T143 PolarHBondContact O-N 2.62Å; I140-L144 PolarHBondContact O-N 2.89Å
141	Y	88.9	Confident	90.6	Very high	7 Å²	7	47.6 Å²	47.6	3%	0.027	24%	0.241	C	C	.	.	H	α-helix	trans	-61.8	-41.3	-172.4	-153	-63.9	0	0	0	111.7	L129 L144 G145 A157 I161 H342 L346 L485 L489 P490 F493	L129-Y141 HydrophobicContact CD1-CD2 4Å; L129-Y141 HydrophobicContact CD1-CE2 3.53Å; L129-Y141 HydrophobicContact CD2-CD2 4.14Å; L129-Y141 HydrophobicContact CD2-CE2 3.62Å; L129-Y141 HydrophobicContact CG-CE2 4.23Å; Y141-L144 WeakPolarHBondContact O-CB 3.34Å; Y141-L144 PolarHBondContact O-N 2.94Å; Y141-G145 PolarHBondContact O-N 3.34Å; Y141-A157 HydrophobicContact CD1-CB 3.78Å; Y141-A157 HydrophobicContact CE1-CB 4.22Å; Y141-I161 HydrophobicContact CD1-CD1 4.16Å; Y141-I161 HydrophobicContact CG-CD1 3.94Å; Y141-H342 HydrophobicContact CE2-CB 4.29Å; Y141-L346 HydrophobicContact CD2-CD1 4.13Å; Y141-L346 HydrophobicContact CG-CD1 4.45Å; Y141-L485 HydrophobicContact CE1-CD2 4.28Å; Y141-L485 HydrophobicContact CE2-CD2 4.43Å; Y141-L489 HydrophobicContact CE1-CB 4.12Å; Y141-L489 HydrophobicContact CE1-CD1 4.01Å; Y141-P490 WeakPolarHBondContact OH-CG 3.42Å; Y141-F493 AromaticContact CD1-CE2 3.9Å; Y141-F493 HydrophobicContact CD1-CE2 3.9Å; Y141-F493 HydrophobicContact CE1-CD2 4.36Å; Y141-F493 AromaticContact CE1-CE2 3.52Å; Y141-F493 HydrophobicContact CE1-CE2 3.52Å; Y141-F493 HydrophobicContact CE1-CZ 4.29Å
142	E	90.5	Very high	90.8	Very high	30 Å²	30	49.7 Å²	49.7	14%	0.14	26%	0.258	C	S	.	.	H	α-helix	trans	-67.8	-36.4	178.4	-57.1	95.2	142	0	0	112.3	I140 L144 G145 H146 K154 F158 S433	I140-E142 VanDerWaalsContact C-N 3.34Å; I140-E142 VanDerWaalsContact CG2-OE2 3.28Å; I140-E142 WeakPolarHBondContact CG2-OE2 3.27Å; I140-E142 PolarHBondContact O-N 3.37Å; E142-L144 VanDerWaalsContact C-N 3.33Å; E142-G145 PolarHBondContact O-N 3.44Å; E142-H146 PolarHBondContact O-N 3.03Å; E142-K154 HydrophobicContact CB-CG 4.25Å; E142-F158 HydrophobicContact CG-CB 4.19Å; E142-S433 PolarHBondContact OE1-OG 3.32Å
143	T	89.6	Confident	90.8	Very high	47 Å²	47	49.9 Å²	49.9	29%	0.288	26%	0.26	S	S	.	.	H	α-helix	trans	-67.1	-38.2	175.5	-60.2	0	0	0	0	110.7	S138 I140 H146 K147	S138-T143 WeakPolarHBondContact OG-CB 3.21Å; S138-T143 WeakPolarHBondContact OG-CG2 3.37Å; I140-T143 PolarHBondContact O-N 2.62Å; T143-H146 WeakPolarHBondContact O-CB 3.36Å; T143-H146 PolarHBondContact O-N 2.75Å; T143-K147 HydrophobicContact CG2-CD 4.4Å; T143-K147 WeakPolarHBondContact O-CG 3.36Å; T143-K147 PolarHBondContact O-N 2.99Å
144	L	91.7	Very high	90.9	Very high	0 Å²	0	52.4 Å²	52.4	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-62.8	-44.3	174.6	-167.7	65.9	0	0	0	111.5	L129 T132 I140 Y141 E142 H146 K147 A148 F493 L497	L129-L144 HydrophobicContact CD1-CD2 4.07Å; T132-L144 WeakPolarHBondContact O-CD1 3.23Å; I140-L144 PolarHBondContact O-N 2.89Å; Y141-L144 WeakPolarHBondContact O-CB 3.34Å; Y141-L144 PolarHBondContact O-N 2.94Å; E142-L144 VanDerWaalsContact C-N 3.33Å; L144-H146 VanDerWaalsContact C-N 3.32Å; L144-H146 PolarHBondContact O-N 3.28Å; L144-K147 PolarHBondContact O-N 3.23Å; L144-A148 PolarHBondContact O-N 3.33Å; L144-F493 HydrophobicContact CB-CD2 4.5Å; L144-F493 HydrophobicContact CD2-CD2 3.82Å; L144-F493 HydrophobicContact CD2-CE2 4.49Å; L144-F493 HydrophobicContact CG-CD2 3.97Å; L144-L497 HydrophobicContact CD1-CD1 3.3Å; L144-L497 HydrophobicContact CG-CD1 3.84Å
145	G	94.1	Very high	91.1	Very high	0 Å²	0	48.6 Å²	48.6	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-60.3	-40.4	173.1	0	0	0	0	0	113	Y141 E142 A148 F149	Y141-G145 PolarHBondContact O-N 3.34Å; E142-G145 PolarHBondContact O-N 3.44Å; G145-A148 PolarHBondContact O-N 3.24Å; G145-F149 PolarHBondContact O-N 2.97Å
146	H	93.6	Very high	91.5	Very high	98 Å²	98	45.8 Å²	45.8	45%	0.454	25%	0.246	S	C	.	.	H	α-helix	trans	-63	-42.3	173.8	-171.1	-93	0	0	0	112.6	E142 T143 L144 A148 G150 K154	E142-H146 PolarHBondContact O-N 3.03Å; T143-H146 WeakPolarHBondContact O-CB 3.36Å; T143-H146 PolarHBondContact O-N 2.75Å; L144-H146 VanDerWaalsContact C-N 3.32Å; L144-H146 PolarHBondContact O-N 3.28Å; H146-A148 VanDerWaalsContact C-N 3.33Å; H146-A148 PolarHBondContact O-N 2.98Å; H146-G150 WeakPolarHBondContact CA-O 3.49Å; H146-G150 WeakPolarHBondContact O-CA 3.36Å; H146-G150 PolarHBondContact O-N 3.26Å; H146-K154 HydrophobicContact CB-CB 4Å; H146-K154 HydrophobicContact CB-CD 4.45Å; H146-K154 HydrophobicContact CB-CG 4.37Å
147	K	92.8	Very high	91.8	Very high	99 Å²	99	45.3 Å²	45.3	43%	0.43	24%	0.241	S	C	.	.	H	α-helix	trans	-66.3	-34.9	177.4	-73.3	177.2	176.3	179.2	0	112.1	G136 G137 T143 L144 L497	G136-K147 WeakPolarHBondContact O-CD 3.46Å; G136-K147 WeakPolarHBondContact O-CE 3.19Å; G136-K147 PolarHBondContact O-NZ 3.45Å; G137-K147 PolarHBondContact O-NZ 2.94Å; T143-K147 HydrophobicContact CG2-CD 4.4Å; T143-K147 WeakPolarHBondContact O-CG 3.36Å; T143-K147 PolarHBondContact O-N 2.99Å; L144-K147 PolarHBondContact O-N 3.23Å; K147-L497 HydrophobicContact CB-CD2 4.17Å
148	A	94.3	Very high	92	Very high	7 Å²	7	44.2 Å²	44.2	6%	0.058	22%	0.223	C	C	.	.	H	α-helix	trans	-76	-52.3	-178.6	0	0	0	0	0	113	L144 G145 H146 F493 R496 L497	L144-A148 PolarHBondContact O-N 3.33Å; G145-A148 PolarHBondContact O-N 3.24Å; H146-A148 VanDerWaalsContact C-N 3.33Å; H146-A148 PolarHBondContact O-N 2.98Å; A148-F493 HydrophobicContact CB-CD1 3.74Å; A148-F493 HydrophobicContact CB-CE1 4.33Å; A148-F493 HydrophobicContact CB-CG 4.35Å; A148-R496 HydrophobicContact CB-CB 4.39Å; A148-R496 HydrophobicContact CB-CG 4.24Å; A148-R496 WeakPolarHBondContact O-CG 3.38Å; A148-R496 PolarHBondContact O-NE 3.49Å; A148-L497 HydrophobicContact CB-CD1 3.98Å; A148-L497 HydrophobicContact CB-CD2 4.14Å; A148-L497 HydrophobicContact CB-CG 3.85Å
149	F	95.8	Very high	92.4	Very high	90 Å²	90	48.8 Å²	48.8	40%	0.395	25%	0.247	S	C	.	.	H	α-helix	trans	-129.5	10.1	-169.2	-63.6	-76.4	0	0	0	113.8	G145 P152 A492 F493 R496	G145-F149 PolarHBondContact O-N 2.97Å; F149-P152 WeakPolarHBondContact O-CD 3.32Å; F149-A492 HydrophobicContact CE2-CB 3.84Å; F149-A492 HydrophobicContact CZ-CB 4.11Å; F149-F493 HydrophobicContact CD2-CD1 4.07Å; F149-F493 HydrophobicContact CD2-CE1 4.11Å; F149-F493 AromaticContact CE2-CD1 3.97Å; F149-F493 HydrophobicContact CE2-CD1 3.97Å; F149-F493 HydrophobicContact CE2-CE1 4.37Å; F149-R496 HydrophobicContact CE1-CB 4.41Å; F149-R496 HydrophobicContact CE1-CG 4.11Å; F149-R496 HydrophobicContact CE2-CB 4.29Å; F149-R496 HydrophobicContact CZ-CB 3.92Å; F149-R496 HydrophobicContact CZ-CG 4.1Å
150	G	94.6	Very high	92.8	Very high	26 Å²	26	47.7 Å²	47.7	27%	0.268	24%	0.241	S	C	.	.	S	Bend	trans	69.1	-145.5	-176.3	0	0	0	0	0	112.2	H146 G153 K154	H146-G150 WeakPolarHBondContact CA-O 3.49Å; H146-G150 WeakPolarHBondContact O-CA 3.36Å; H146-G150 PolarHBondContact O-N 3.26Å; G150-G153 PolarHBondContact O-N 3.46Å; G150-K154 PolarHBondContact O-N 3.27Å; G150-K154 VanDerWaalsContact O-N 3.11Å
151	W	91.8	Very high	93.1	Very high	179 Å²	179	44 Å²	44	68%	0.678	22%	0.223	S	C	*	.	H	α-helix	trans	-57.4	-43.4	-176.2	-174.9	89.6	0	0	0	114.4	G153 K154 M155	W151-G153 PolarHBondContact O-N 3.04Å; W151-K154 WeakPolarHBondContact O-CB 3.39Å; W151-K154 PolarHBondContact O-N 3.42Å; W151-M155 HydrophobicContact CD2-CG 3.77Å; W151-M155 VanDerWaalsContact CE2-CG 3.45Å; W151-M155 HydrophobicContact CE3-CG 4.09Å; W151-M155 HydrophobicContact CG-CG 4.41Å; W151-M155 HydrophobicContact CH2-CG 3.88Å; W151-M155 HydrophobicContact CZ2-CG 3.52Å; W151-M155 HydrophobicContact CZ2-SD 3.97Å; W151-M155 HydrophobicContact CZ3-CG 4.14Å; W151-M155 WeakPolarHBondContact O-CG 3.45Å; W151-M155 PolarHBondContact O-N 2.95Å
152	P	95.4	Very high	93.3	Very high	84 Å²	84	45 Å²	45	55%	0.545	23%	0.228	S	C	.	.	H	α-helix	trans	-57.8	-44.4	176	-26.4	34.6	0	0	0	113.7	F149 K154 M155 A156	F149-P152 WeakPolarHBondContact O-CD 3.32Å; P152-K154 VanDerWaalsContact C-N 3.35Å; P152-K154 PolarHBondContact O-N 3.49Å; P152-M155 PolarHBondContact O-N 3.43Å; P152-A156 WeakPolarHBondContact O-CB 3.27Å; P152-A156 PolarHBondContact O-N 3.26Å
153	G	94.4	Very high	93.5	Very high	4 Å²	4	45.9 Å²	45.9	4%	0.041	23%	0.233	C	C	.	.	H	α-helix	trans	-65.8	-38.3	178.5	0	0	0	0	0	112.6	G150 W151 A157	G150-G153 PolarHBondContact O-N 3.46Å; W151-G153 PolarHBondContact O-N 3.04Å; G153-A157 PolarHBondContact O-N 3.32Å; G153-A157 VanDerWaalsContact O-N 3.12Å
154	K	92.8	Very high	93.8	Very high	57 Å²	57	44 Å²	44	25%	0.248	22%	0.221	C	C	.	.	H	α-helix	trans	-60.6	-48.4	173.7	-172	-175.8	174.1	-179.5	0	111.4	E142 H146 G150 W151 P152 F158	E142-K154 HydrophobicContact CB-CG 4.25Å; H146-K154 HydrophobicContact CB-CB 4Å; H146-K154 HydrophobicContact CB-CD 4.45Å; H146-K154 HydrophobicContact CB-CG 4.37Å; G150-K154 PolarHBondContact O-N 3.27Å; G150-K154 VanDerWaalsContact O-N 3.11Å; W151-K154 WeakPolarHBondContact O-CB 3.39Å; W151-K154 PolarHBondContact O-N 3.42Å; P152-K154 VanDerWaalsContact C-N 3.35Å; P152-K154 PolarHBondContact O-N 3.49Å; K154-F158 VanDerWaalsContact O-CB 3.28Å; K154-F158 WeakPolarHBondContact O-CB 3.49Å; K154-F158 PolarHBondContact O-N 3.23Å
155	M	93.3	Very high	93.9	Very high	26 Å²	26	44.4 Å²	44.4	13%	0.128	22%	0.223	C	C	.	.	H	α-helix	trans	-67.8	-40	-178.9	-67.6	-58.4	96.6	0	0	112	W151 P152 F158 I159 L437	W151-M155 HydrophobicContact CD2-CG 3.77Å; W151-M155 VanDerWaalsContact CE2-CG 3.45Å; W151-M155 HydrophobicContact CE3-CG 4.09Å; W151-M155 HydrophobicContact CG-CG 4.41Å; W151-M155 HydrophobicContact CH2-CG 3.88Å; W151-M155 HydrophobicContact CZ2-CG 3.52Å; W151-M155 HydrophobicContact CZ2-SD 3.97Å; W151-M155 HydrophobicContact CZ3-CG 4.14Å; W151-M155 WeakPolarHBondContact O-CG 3.45Å; W151-M155 PolarHBondContact O-N 2.95Å; P152-M155 PolarHBondContact O-N 3.43Å; M155-F158 PolarHBondContact O-N 2.95Å; M155-I159 WeakPolarHBondContact O-CB 3.28Å; M155-I159 VanDerWaalsContact O-CG1 3.28Å; M155-I159 WeakPolarHBondContact O-CG1 3.3Å; M155-I159 PolarHBondContact O-N 2.81Å; M155-L437 HydrophobicContact CE-CD1 3.87Å
156	A	94.8	Very high	93.9	Very high	33 Å²	33	45.8 Å²	45.8	27%	0.273	23%	0.23	S	C	.	.	H	α-helix	trans	-60.4	-47.3	176.8	0	0	0	0	0	111.8	P152 S160 L489	P152-A156 WeakPolarHBondContact O-CB 3.27Å; P152-A156 PolarHBondContact O-N 3.26Å; A156-S160 VanDerWaalsContact O-CB 3.31Å; A156-S160 WeakPolarHBondContact O-CB 3.36Å; A156-S160 PolarHBondContact O-N 3.46Å; A156-S160 VanDerWaalsContact O-N 3.08Å; A156-S160 PolarHBondContact O-OG 2.86Å; A156-L489 HydrophobicContact CB-CD2 4.08Å
157	A	93.1	Very high	93.9	Very high	0 Å²	0	41.2 Å²	41.2	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-59.4	-50.4	173.9	0	0	0	0	0	111.8	Y141 G153 I159 S160 I161 L489 F493	Y141-A157 HydrophobicContact CD1-CB 3.78Å; Y141-A157 HydrophobicContact CE1-CB 4.22Å; G153-A157 PolarHBondContact O-N 3.32Å; G153-A157 VanDerWaalsContact O-N 3.12Å; A157-I159 PolarHBondContact O-N 3.47Å; A157-S160 PolarHBondContact O-N 3.46Å; A157-I161 WeakPolarHBondContact O-CB 3.23Å; A157-I161 WeakPolarHBondContact O-CD1 3.2Å; A157-I161 VanDerWaalsContact O-CG1 3.23Å; A157-I161 WeakPolarHBondContact O-CG1 3.49Å; A157-I161 PolarHBondContact O-N 2.8Å; A157-L489 HydrophobicContact CB-CD1 4.34Å; A157-F493 HydrophobicContact CB-CZ 4.41Å
158	F	91.8	Very high	94	Very high	26 Å²	26	37 Å²	37	11%	0.114	19%	0.192	C	C	.	.	H	α-helix	trans	-57.7	-51.3	-179.2	174.9	-95.6	0	0	0	112.9	E142 K154 M155 S160 I161 I162 S433 L437	E142-F158 HydrophobicContact CG-CB 4.19Å; K154-F158 VanDerWaalsContact O-CB 3.28Å; K154-F158 WeakPolarHBondContact O-CB 3.49Å; K154-F158 PolarHBondContact O-N 3.23Å; M155-F158 PolarHBondContact O-N 2.95Å; F158-S160 VanDerWaalsContact C-N 3.33Å; F158-S160 PolarHBondContact O-N 2.97Å; F158-I161 PolarHBondContact O-N 3.48Å; F158-I162 HydrophobicContact CD1-CD1 4.22Å; F158-I162 HydrophobicContact CD2-CD1 4.24Å; F158-I162 HydrophobicContact CE1-CD1 3.51Å; F158-I162 HydrophobicContact CE2-CD1 3.55Å; F158-I162 HydrophobicContact CE2-CG1 4.38Å; F158-I162 HydrophobicContact CZ-CD1 3.13Å; F158-I162 HydrophobicContact CZ-CG1 4.29Å; F158-I162 WeakPolarHBondContact O-CG1 3.42Å; F158-I162 PolarHBondContact O-N 3.38Å; F158-S433 WeakPolarHBondContact CE2-O 3.45Å; F158-L437 HydrophobicContact CD1-CD2 4.11Å; F158-L437 HydrophobicContact CE1-CD2 3.43Å; F158-L437 VanDerWaalsContact CE1-CD2 3.43Å; F158-L437 HydrophobicContact CE2-CB 4Å; F158-L437 HydrophobicContact CE2-CD2 3.89Å; F158-L437 HydrophobicContact CZ-CB 4.11Å; F158-L437 HydrophobicContact CZ-CD2 3.28Å; F158-L437 HydrophobicContact CZ-CG 4.29Å
159	I	94.2	Very high	94	Very high	98 Å²	98	36.6 Å²	36.6	50%	0.503	19%	0.189	S	C	.	.	H	α-helix	trans	-63	-42.3	-179.3	-68	168.9	0	0	0	110.3	M155 A157 I162 M163	M155-I159 WeakPolarHBondContact O-CB 3.28Å; M155-I159 VanDerWaalsContact O-CG1 3.28Å; M155-I159 WeakPolarHBondContact O-CG1 3.3Å; M155-I159 PolarHBondContact O-N 2.81Å; A157-I159 PolarHBondContact O-N 3.47Å; I159-I162 PolarHBondContact O-N 3.21Å; I159-M163 WeakPolarHBondContact O-CB 3.38Å; I159-M163 PolarHBondContact O-N 3.29Å
160	S	95.1	Very high	94	Very high	7 Å²	7	32.3 Å²	32.3	5%	0.049	17%	0.171	C	C	.	.	H	α-helix	trans	-66.3	-42.5	-179	-52.5	0	0	0	0	112.1	A156 A157 F158 M163 Q164 M484	A156-S160 VanDerWaalsContact O-CB 3.31Å; A156-S160 WeakPolarHBondContact O-CB 3.36Å; A156-S160 PolarHBondContact O-N 3.46Å; A156-S160 VanDerWaalsContact O-N 3.08Å; A156-S160 PolarHBondContact O-OG 2.86Å; A157-S160 PolarHBondContact O-N 3.46Å; F158-S160 VanDerWaalsContact C-N 3.33Å; F158-S160 PolarHBondContact O-N 2.97Å; S160-M163 PolarHBondContact O-N 3.13Å; S160-Q164 VanDerWaalsContact O-CB 3.28Å; S160-Q164 WeakPolarHBondContact O-CB 3.26Å; S160-Q164 PolarHBondContact O-N 3.38Å; S160-M484 WeakPolarHBondContact OG-CG 3.28Å
161	I	92.8	Very high	94	Very high	7 Å²	7	31.1 Å²	31.1	4%	0.036	16%	0.158	C	C	.	.	H	α-helix	trans	-63.9	-47.1	176.7	-69.4	166.8	0	0	0	110.5	Y141 A157 F158 Q164 N165 P343 L485	Y141-I161 HydrophobicContact CD1-CD1 4.16Å; Y141-I161 HydrophobicContact CG-CD1 3.94Å; A157-I161 WeakPolarHBondContact O-CB 3.23Å; A157-I161 WeakPolarHBondContact O-CD1 3.2Å; A157-I161 VanDerWaalsContact O-CG1 3.23Å; A157-I161 WeakPolarHBondContact O-CG1 3.49Å; A157-I161 PolarHBondContact O-N 2.8Å; F158-I161 PolarHBondContact O-N 3.48Å; I161-Q164 PolarHBondContact O-N 2.92Å; I161-N165 WeakPolarHBondContact CG2-ND2 3.37Å; I161-N165 WeakPolarHBondContact O-CB 3.41Å; I161-N165 PolarHBondContact O-N 2.92Å; I161-N165 PolarHBondContact O-ND2 2.91Å; I161-P343 HydrophobicContact CG1-CB 4.34Å; I161-P343 HydrophobicContact CG1-CG 4.33Å; I161-P343 HydrophobicContact CG2-CB 4.31Å; I161-L485 HydrophobicContact CG1-CD2 3.94Å
162	I	93.4	Very high	94.2	Very high	26 Å²	26	23 Å²	23	13%	0.133	13%	0.127	C	C	.	.	H	α-helix	trans	-62.2	-46.9	177.8	-74.2	-170.5	0	0	0	110.9	F158 I159 Q164 N165 I166 I430 I434	F158-I162 HydrophobicContact CD1-CD1 4.22Å; F158-I162 HydrophobicContact CD2-CD1 4.24Å; F158-I162 HydrophobicContact CE1-CD1 3.51Å; F158-I162 HydrophobicContact CE2-CD1 3.55Å; F158-I162 HydrophobicContact CE2-CG1 4.38Å; F158-I162 HydrophobicContact CZ-CD1 3.13Å; F158-I162 HydrophobicContact CZ-CG1 4.29Å; F158-I162 WeakPolarHBondContact O-CG1 3.42Å; F158-I162 PolarHBondContact O-N 3.38Å; I159-I162 PolarHBondContact O-N 3.21Å; I162-Q164 VanDerWaalsContact C-N 3.35Å; I162-Q164 PolarHBondContact O-N 2.92Å; I162-N165 PolarHBondContact O-N 3.43Å; I162-I166 HydrophobicContact CG2-CD1 3.51Å; I162-I166 HydrophobicContact CG2-CG1 4.19Å; I162-I166 WeakPolarHBondContact O-CB 3.49Å; I162-I166 VanDerWaalsContact O-CG1 3.26Å; I162-I166 WeakPolarHBondContact O-CG1 3.41Å; I162-I166 PolarHBondContact O-N 3.26Å; I162-I430 HydrophobicContact CG1-CG2 4.44Å; I162-I434 HydrophobicContact CD1-CD1 4.47Å; I162-I434 HydrophobicContact CD1-CG1 3.9Å
163	M	94.6	Very high	94.2	Very high	49 Å²	49	19 Å²	19	24%	0.241	10%	0.101	C	C	.	.	H	α-helix	trans	-62	-43.4	-179.9	-171.3	164.5	67	0	0	111.3	I159 S160 G167 F476 I477 S480 A481	I159-M163 WeakPolarHBondContact O-CB 3.38Å; I159-M163 PolarHBondContact O-N 3.29Å; S160-M163 PolarHBondContact O-N 3.13Å; M163-G167 PolarHBondContact O-N 2.9Å; M163-F476 HydrophobicContact SD-CE1 4.14Å; M163-I477 HydrophobicContact CG-CD1 3.85Å; M163-S480 VanDerWaalsContact CE-OG 3.26Å; M163-S480 WeakPolarHBondContact CE-OG 3.17Å; M163-A481 HydrophobicContact CB-CB 3.99Å; M163-A481 HydrophobicContact CE-CB 3.55Å; M163-A481 HydrophobicContact CG-CB 4.01Å
164	Q	94.7	Very high	94.3	Very high	8 Å²	8	19.1 Å²	19.1	4%	0.037	10%	0.101	C	C	.	.	H	α-helix	trans	-60.6	-47.9	175.5	179.5	55.3	54.5	0	0	112.2	S160 I161 I162 G167 A168 F337 V340 A481 L485	S160-Q164 VanDerWaalsContact O-CB 3.28Å; S160-Q164 WeakPolarHBondContact O-CB 3.26Å; S160-Q164 PolarHBondContact O-N 3.38Å; I161-Q164 PolarHBondContact O-N 2.92Å; I162-Q164 VanDerWaalsContact C-N 3.35Å; I162-Q164 PolarHBondContact O-N 2.92Å; Q164-G167 PolarHBondContact O-N 2.74Å; Q164-A168 PolarHBondContact O-N 2.93Å; Q164-F337 VanDerWaalsContact NE2-CE2 3.29Å; Q164-V340 HydrophobicContact CG-CG1 4Å; Q164-V340 HydrophobicContact CG-CG2 4.16Å; Q164-A481 HydrophobicContact CB-CB 3.9Å; Q164-L485 HydrophobicContact CB-CD1 3.68Å; Q164-L485 HydrophobicContact CG-CD1 3.98Å
165	N	93.6	Very high	94.3	Very high	8 Å²	8	16.4 Å²	16.4	4%	0.043	9%	0.089	C	C	.	.	H	α-helix	trans	-71.7	-35	-176.8	-74.1	-30.9	0	0	0	112.3	I161 I162 M169 V426 I430	I161-N165 WeakPolarHBondContact CG2-ND2 3.37Å; I161-N165 WeakPolarHBondContact O-CB 3.41Å; I161-N165 PolarHBondContact O-N 2.92Å; I161-N165 PolarHBondContact O-ND2 2.91Å; I162-N165 PolarHBondContact O-N 3.43Å; N165-M169 VanDerWaalsContact O-CB 3.23Å; N165-M169 WeakPolarHBondContact O-CB 3.32Å; N165-M169 PolarHBondContact O-N 3.01Å; N165-V426 HydrophobicContact CB-CG1 3.7Å; N165-V426 VanDerWaalsContact O-CG1 3.23Å; N165-V426 WeakPolarHBondContact O-CG1 3.3Å; N165-I430 HydrophobicContact CB-CD1 3.57Å; N165-I430 HydrophobicContact CB-CG1 3.37Å
166	I	94.8	Very high	94.4	Very high	30 Å²	30	15.3 Å²	15.3	15%	0.154	8%	0.084	C	C	.	.	H	α-helix	trans	-61.9	-45.5	168.8	-72.5	174.1	0	0	0	109.9	I162 A168 M169 S170 I430 F459 N460 L463	I162-I166 HydrophobicContact CG2-CD1 3.51Å; I162-I166 HydrophobicContact CG2-CG1 4.19Å; I162-I166 WeakPolarHBondContact O-CB 3.49Å; I162-I166 VanDerWaalsContact O-CG1 3.26Å; I162-I166 WeakPolarHBondContact O-CG1 3.41Å; I162-I166 PolarHBondContact O-N 3.26Å; I166-A168 PolarHBondContact O-N 2.81Å; I166-M169 PolarHBondContact O-N 3.4Å; I166-S170 VanDerWaalsContact O-CB 3.22Å; I166-S170 WeakPolarHBondContact O-CB 3.44Å; I166-S170 PolarHBondContact O-N 3.43Å; I166-S170 PolarHBondContact O-OG 3.15Å; I166-I430 HydrophobicContact CG1-CD1 4.14Å; I166-F459 HydrophobicContact CD1-CD1 4.29Å; I166-F459 HydrophobicContact CD1-CE1 3.96Å; I166-F459 HydrophobicContact CG2-CD1 4.44Å; I166-F459 HydrophobicContact CG2-CE1 3.91Å; I166-N460 PolarHBondContact O-OD1 2.91Å; I166-L463 HydrophobicContact CG2-CD1 4.22Å
167	G	94.6	Very high	94.4	Very high	1 Å²	1	14.4 Å²	14.4	1%	0.01	7%	0.074	C	C	.	.	H	α-helix	trans	-58.5	-48.3	177.5	0	0	0	0	0	113.2	M163 Q164 S170 S171	M163-G167 PolarHBondContact O-N 2.9Å; Q164-G167 PolarHBondContact O-N 2.74Å; G167-S170 PolarHBondContact O-N 3.47Å; G167-S171 PolarHBondContact O-N 2.94Å; G167-S171 PolarHBondContact O-OG 3.38Å
168	A	93.9	Very high	94.3	Very high	10 Å²	10	18 Å²	18	8%	0.083	9%	0.088	C	C	.	.	H	α-helix	trans	-64.2	-41.7	176.3	0	0	0	0	0	112.7	Q164 I166 S171 Y172 F337 V426	Q164-A168 PolarHBondContact O-N 2.93Å; I166-A168 PolarHBondContact O-N 2.81Å; A168-S171 PolarHBondContact O-N 2.78Å; A168-S171 PolarHBondContact O-OG 2.99Å; A168-Y172 HydrophobicContact CB-CE2 4.31Å; A168-Y172 WeakPolarHBondContact O-CD2 3.22Å; A168-Y172 WeakPolarHBondContact O-CE2 3.44Å; A168-Y172 VanDerWaalsContact O-CG 3.28Å; A168-Y172 PolarHBondContact O-N 3.29Å; A168-Y172 VanDerWaalsContact O-N 3.17Å; A168-F337 HydrophobicContact CB-CE2 4.45Å; A168-F337 HydrophobicContact CB-CZ 4.29Å; A168-V426 HydrophobicContact CB-CG1 4.26Å
169	M	94.5	Very high	94.3	Very high	0 Å²	0	16.8 Å²	16.8	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-64.5	-42.6	175.7	-177.4	175.6	-41.4	0	0	112.1	N165 I166 Y172 L173 V423 V426 L427 I430 I456 L457 N460	N165-M169 VanDerWaalsContact O-CB 3.23Å; N165-M169 WeakPolarHBondContact O-CB 3.32Å; N165-M169 PolarHBondContact O-N 3.01Å; I166-M169 PolarHBondContact O-N 3.4Å; M169-Y172 PolarHBondContact O-N 3.06Å; M169-L173 HydrophobicContact CG-CD1 4.36Å; M169-L173 WeakPolarHBondContact O-CG 3.26Å; M169-L173 PolarHBondContact O-N 2.88Å; M169-V423 HydrophobicContact CG-CG1 3.82Å; M169-V423 HydrophobicContact SD-CG1 4.09Å; M169-V426 HydrophobicContact CB-CG1 4.4Å; M169-V426 HydrophobicContact CE-CG1 4.48Å; M169-L427 HydrophobicContact CE-CB 3.63Å; M169-L427 HydrophobicContact CE-CD1 4.23Å; M169-L427 HydrophobicContact CE-CG 4.02Å; M169-L427 HydrophobicContact SD-CD1 4.45Å; M169-I430 HydrophobicContact CE-CD1 3.56Å; M169-I456 HydrophobicContact CE-CG2 4.09Å; M169-I456 HydrophobicContact SD-CG2 4.18Å; M169-L457 HydrophobicContact SD-CD1 4.45Å; M169-N460 HydrophobicContact CG-CB 4.23Å; M169-N460 HydrophobicContact SD-CB 4.11Å
170	S	95.4	Very high	94.3	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-62.1	-42.2	177.8	-65.7	0	0	0	0	111.5	I166 G167 L173 F174 N460 V464	I166-S170 VanDerWaalsContact O-CB 3.22Å; I166-S170 WeakPolarHBondContact O-CB 3.44Å; I166-S170 PolarHBondContact O-N 3.43Å; I166-S170 PolarHBondContact O-OG 3.15Å; G167-S170 PolarHBondContact O-N 3.47Å; S170-L173 PolarHBondContact O-N 3.38Å; S170-F174 WeakPolarHBondContact O-CB 3.44Å; S170-F174 PolarHBondContact O-N 2.85Å; S170-N460 PolarHBondContact N-OD1 3.11Å; S170-N460 PolarHBondContact OG-OD1 3.38Å; S170-V464 WeakPolarHBondContact O-CG2 3.2Å
171	S	95.4	Very high	94.2	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-67.2	-36	177	57.6	0	0	0	0	113.2	S94 G167 A168 F174 I175	S94-S171 WeakPolarHBondContact CB-OG 3.12Å; S94-S171 WeakPolarHBondContact OG-CB 3.32Å; S94-S171 PolarHBondContact OG-OG 3.41Å; G167-S171 PolarHBondContact O-N 2.94Å; G167-S171 PolarHBondContact O-OG 3.38Å; A168-S171 PolarHBondContact O-N 2.78Å; A168-S171 PolarHBondContact O-OG 2.99Å; S171-F174 WeakPolarHBondContact O-CB 3.4Å; S171-F174 PolarHBondContact O-N 3.44Å; S171-I175 WeakPolarHBondContact O-CG1 3.29Å; S171-I175 PolarHBondContact O-N 2.9Å; S171-I175 VanDerWaalsContact O-N 3.09Å
172	Y	95.3	Very high	93.9	Very high	8 Å²	8	15.2 Å²	15.2	3%	0.031	7%	0.073	C	C	.	.	H	α-helix	trans	-63.6	-45.1	171.8	-61.9	-42.9	0	0	0	112.5	G93 S94 A168 M169 F174 I175 V176 V419 T422 V423 V426	G93-Y172 WeakPolarHBondContact CA-OH 3.48Å; S94-Y172 VanDerWaalsContact N-CE1 3.25Å; A168-Y172 HydrophobicContact CB-CE2 4.31Å; A168-Y172 WeakPolarHBondContact O-CD2 3.22Å; A168-Y172 WeakPolarHBondContact O-CE2 3.44Å; A168-Y172 VanDerWaalsContact O-CG 3.28Å; A168-Y172 PolarHBondContact O-N 3.29Å; A168-Y172 VanDerWaalsContact O-N 3.17Å; M169-Y172 PolarHBondContact O-N 3.06Å; Y172-F174 VanDerWaalsContact C-N 3.28Å; Y172-F174 PolarHBondContact O-N 3.39Å; Y172-I175 PolarHBondContact O-N 3.31Å; Y172-V176 WeakPolarHBondContact O-CG2 3.34Å; Y172-V176 PolarHBondContact O-N 3.04Å; Y172-V419 HydrophobicContact CD1-CB 3.69Å; Y172-V419 HydrophobicContact CD1-CG1 3.7Å; Y172-V419 HydrophobicContact CE1-CG1 4.25Å; Y172-V419 HydrophobicContact CG-CB 4.14Å; Y172-T422 HydrophobicContact CD2-CG2 4.47Å; Y172-T422 HydrophobicContact CE1-CG2 4.41Å; Y172-T422 HydrophobicContact CE2-CG2 3.67Å; Y172-V423 HydrophobicContact CD2-CG2 3.84Å; Y172-V423 HydrophobicContact CG-CG2 4.07Å; Y172-V426 HydrophobicContact CE2-CG2 3.99Å
173	L	96	Very high	93.8	Very high	0 Å²	0	14.2 Å²	14.2	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-67.1	-31	177.1	-70.2	-179	0	0	0	111.9	M169 S170 V176 K177 V205 I213 L457 N460 V464	M169-L173 HydrophobicContact CG-CD1 4.36Å; M169-L173 WeakPolarHBondContact O-CG 3.26Å; M169-L173 PolarHBondContact O-N 2.88Å; S170-L173 PolarHBondContact O-N 3.38Å; L173-V176 PolarHBondContact O-N 2.83Å; L173-K177 WeakPolarHBondContact O-CB 3.06Å; L173-K177 PolarHBondContact O-N 2.89Å; L173-V205 HydrophobicContact CB-CG2 3.95Å; L173-V205 HydrophobicContact CD2-CG2 4.03Å; L173-V205 HydrophobicContact CG-CG2 4.48Å; L173-V205 WeakPolarHBondContact O-CG2 3.32Å; L173-I213 HydrophobicContact CD2-CD1 3.57Å; L173-L457 HydrophobicContact CD1-CD1 4.08Å; L173-N460 HydrophobicContact CD1-CB 3.81Å; L173-V464 HydrophobicContact CB-CG1 4.46Å; L173-V464 HydrophobicContact CB-CG2 3.94Å
174	F	95.7	Very high	93.6	Very high	8 Å²	8	13.6 Å²	13.6	4%	0.035	7%	0.066	C	C	.	.	H	α-helix	trans	-61.7	-48.3	171.9	-168.2	-76.7	0	0	0	110.7	S170 S171 Y172 V176 K177 Y178 V464 I470 I473	S170-F174 WeakPolarHBondContact O-CB 3.44Å; S170-F174 PolarHBondContact O-N 2.85Å; S171-F174 WeakPolarHBondContact O-CB 3.4Å; S171-F174 PolarHBondContact O-N 3.44Å; Y172-F174 VanDerWaalsContact C-N 3.28Å; Y172-F174 PolarHBondContact O-N 3.39Å; F174-V176 VanDerWaalsContact C-N 3.28Å; F174-V176 PolarHBondContact O-N 3.43Å; F174-K177 WeakPolarHBondContact O-CB 3.47Å; F174-K177 PolarHBondContact O-N 3.38Å; F174-Y178 AromaticContact CD1-CD2 3.55Å; F174-Y178 HydrophobicContact CD1-CD2 3.55Å; F174-Y178 AromaticContact CD1-CE2 3.86Å; F174-Y178 HydrophobicContact CD1-CE2 3.86Å; F174-Y178 HydrophobicContact CD2-CD2 4.43Å; F174-Y178 AromaticContact CD2-CE2 3.98Å; F174-Y178 HydrophobicContact CD2-CE2 3.98Å; F174-Y178 AromaticContact CE1-CD2 3.25Å; F174-Y178 HydrophobicContact CE1-CD2 3.25Å; F174-Y178 AromaticContact CE1-CE2 3.32Å; F174-Y178 HydrophobicContact CE1-CE2 3.32Å; F174-Y178 HydrophobicContact CE1-CG 4.11Å; F174-Y178 HydrophobicContact CE2-CD2 4.2Å; F174-Y178 AromaticContact CE2-CE2 3.47Å; F174-Y178 HydrophobicContact CE2-CE2 3.47Å; F174-Y178 VanDerWaalsContact CE2-CE2 3.47Å; F174-Y178 HydrophobicContact CG-CD2 4.14Å; F174-Y178 HydrophobicContact CG-CE2 4.16Å; F174-Y178 AromaticContact CZ-CD2 3.63Å; F174-Y178 HydrophobicContact CZ-CD2 3.63Å; F174-Y178 AromaticContact CZ-CE2 3.1Å; F174-Y178 HydrophobicContact CZ-CE2 3.1Å; F174-Y178 AromaticContact CZ-CZ 3.72Å; F174-Y178 WeakPolarHBondContact O-CD2 3.22Å; F174-Y178 PolarHBondContact O-N 2.86Å; F174-Y178 VanDerWaalsContact O-N 3.11Å; F174-V464 HydrophobicContact CB-CG1 4.07Å; F174-V464 HydrophobicContact CD2-CG1 4.29Å; F174-I470 HydrophobicContact CB-CD1 4.46Å; F174-I470 HydrophobicContact CD1-CB 3.73Å; F174-I470 HydrophobicContact CD1-CD1 3.99Å; F174-I470 HydrophobicContact CD1-CG1 4.09Å; F174-I470 HydrophobicContact CE1-CB 3.72Å; F174-I470 HydrophobicContact CE1-CG2 4.4Å; F174-I470 HydrophobicContact CG-CB 4.16Å; F174-I470 HydrophobicContact CG-CD1 4.44Å; F174-I470 HydrophobicContact CG-CG1 4.28Å; F174-I470 HydrophobicContact CZ-CB 4.12Å; F174-I473 HydrophobicContact CB-CD1 4.49Å; F174-I473 HydrophobicContact CD2-CD1 4.22Å
175	I	93.9	Very high	93.2	Very high	0 Å²	0	15.3 Å²	15.3	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-57.3	-44.1	175.1	-64.2	160.9	0	0	0	110.4	L97 S171 Y172 K177 Y178 E179 V415 V419 I470	L97-I175 HydrophobicContact CD1-CD1 3.5Å; L97-I175 VanDerWaalsContact CD1-CD1 3.5Å; L97-I175 HydrophobicContact CD1-CG1 3.83Å; L97-I175 HydrophobicContact CD1-CG2 4.36Å; S171-I175 WeakPolarHBondContact O-CG1 3.29Å; S171-I175 PolarHBondContact O-N 2.9Å; S171-I175 VanDerWaalsContact O-N 3.09Å; Y172-I175 PolarHBondContact O-N 3.31Å; I175-K177 VanDerWaalsContact C-N 3.34Å; I175-K177 PolarHBondContact O-N 3.42Å; I175-Y178 PolarHBondContact O-N 3.49Å; I175-E179 HydrophobicContact CG2-CB 4.47Å; I175-E179 HydrophobicContact CG2-CG 4.03Å; I175-E179 VanDerWaalsContact O-CB 3.31Å; I175-E179 WeakPolarHBondContact O-CB 3.19Å; I175-E179 PolarHBondContact O-N 3.27Å; I175-V415 HydrophobicContact CG2-CG1 4.19Å; I175-V419 HydrophobicContact CD1-CG1 4.05Å; I175-V419 HydrophobicContact CG2-CG2 4.29Å; I175-I470 HydrophobicContact CG1-CD1 4.17Å
176	V	95.1	Very high	92.9	Very high	2 Å²	2	15.3 Å²	15.3	1%	0.012	7%	0.073	C	C	.	.	H	α-helix	trans	-60.2	-42.8	175.9	174.7	0	0	0	0	111.8	Y172 L173 F174 Y178 L180 V205 V208 L416 V419	Y172-V176 WeakPolarHBondContact O-CG2 3.34Å; Y172-V176 PolarHBondContact O-N 3.04Å; L173-V176 PolarHBondContact O-N 2.83Å; F174-V176 VanDerWaalsContact C-N 3.28Å; F174-V176 PolarHBondContact O-N 3.43Å; V176-Y178 PolarHBondContact O-N 3.29Å; V176-L180 HydrophobicContact CG1-CD2 4.28Å; V176-L180 WeakPolarHBondContact O-CB 3.03Å; V176-L180 PolarHBondContact O-N 2.93Å; V176-V205 HydrophobicContact CB-CG2 4.46Å; V176-V205 HydrophobicContact CG1-CG2 4.35Å; V176-V208 HydrophobicContact CG1-CB 4.16Å; V176-V208 HydrophobicContact CG1-CG1 4.13Å; V176-V208 HydrophobicContact CG1-CG2 4.17Å; V176-L416 HydrophobicContact CB-CD2 4.4Å; V176-L416 HydrophobicContact CG2-CD2 4.11Å; V176-V419 HydrophobicContact CG2-CG2 4.09Å
177	K	94.5	Very high	92.5	Very high	15 Å²	15	19.7 Å²	19.7	7%	0.065	9%	0.091	C	C	.	.	H	α-helix	trans	-60.2	-40.6	179.1	168.9	179.2	160.7	179.5	0	112.3	L173 F174 I175 P181 G201 N202 V205 V464 I465	L173-K177 WeakPolarHBondContact O-CB 3.06Å; L173-K177 PolarHBondContact O-N 2.89Å; F174-K177 WeakPolarHBondContact O-CB 3.47Å; F174-K177 PolarHBondContact O-N 3.38Å; I175-K177 VanDerWaalsContact C-N 3.34Å; I175-K177 PolarHBondContact O-N 3.42Å; K177-P181 VanDerWaalsContact O-CD 3.25Å; K177-P181 WeakPolarHBondContact O-CD 3.27Å; K177-P181 VanDerWaalsContact O-CG 3.29Å; K177-P181 WeakPolarHBondContact O-CG 3.27Å; K177-G201 WeakPolarHBondContact O-CA 3.39Å; K177-N202 WeakPolarHBondContact CD-OD1 3.31Å; K177-N202 WeakPolarHBondContact CE-OD1 3.48Å; K177-N202 PolarHBondContact NZ-OD1 2.91Å; K177-V205 HydrophobicContact CB-CB 4.09Å; K177-V205 HydrophobicContact CB-CG1 4.38Å; K177-V205 HydrophobicContact CB-CG2 4.42Å; K177-V464 HydrophobicContact CB-CG1 4.22Å; K177-V464 HydrophobicContact CD-CG1 3.8Å; K177-V464 PolarHBondContact NZ-O 3.37Å; K177-I465 PolarHBondContact NZ-O 3.18Å
178	Y	91.7	Very high	92.1	Very high	75 Å²	75	24 Å²	24	29%	0.294	11%	0.114	S	C	.	.	H	α-helix	trans	-93.9	-36.9	-174.4	-74.7	-89.6	0	0	0	113.9	F174 I175 V176	F174-Y178 AromaticContact CD1-CD2 3.55Å; F174-Y178 HydrophobicContact CD1-CD2 3.55Å; F174-Y178 AromaticContact CD1-CE2 3.86Å; F174-Y178 HydrophobicContact CD1-CE2 3.86Å; F174-Y178 HydrophobicContact CD2-CD2 4.43Å; F174-Y178 AromaticContact CD2-CE2 3.98Å; F174-Y178 HydrophobicContact CD2-CE2 3.98Å; F174-Y178 AromaticContact CE1-CD2 3.25Å; F174-Y178 HydrophobicContact CE1-CD2 3.25Å; F174-Y178 AromaticContact CE1-CE2 3.32Å; F174-Y178 HydrophobicContact CE1-CE2 3.32Å; F174-Y178 HydrophobicContact CE1-CG 4.11Å; F174-Y178 HydrophobicContact CE2-CD2 4.2Å; F174-Y178 AromaticContact CE2-CE2 3.47Å; F174-Y178 HydrophobicContact CE2-CE2 3.47Å; F174-Y178 VanDerWaalsContact CE2-CE2 3.47Å; F174-Y178 HydrophobicContact CG-CD2 4.14Å; F174-Y178 HydrophobicContact CG-CE2 4.16Å; F174-Y178 AromaticContact CZ-CD2 3.63Å; F174-Y178 HydrophobicContact CZ-CD2 3.63Å; F174-Y178 AromaticContact CZ-CE2 3.1Å; F174-Y178 HydrophobicContact CZ-CE2 3.1Å; F174-Y178 AromaticContact CZ-CZ 3.72Å; F174-Y178 WeakPolarHBondContact O-CD2 3.22Å; F174-Y178 PolarHBondContact O-N 2.86Å; F174-Y178 VanDerWaalsContact O-N 3.11Å; I175-Y178 PolarHBondContact O-N 3.49Å; V176-Y178 PolarHBondContact O-N 3.29Å
179	E	92.4	Very high	91.5	Very high	0 Å²	0	30.5 Å²	30.5	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-86	-32	-175	-67	-64.3	143.3	0	0	113.4	I175 E182 V183 L395 H396 R412 L416	I175-E179 HydrophobicContact CG2-CB 4.47Å; I175-E179 HydrophobicContact CG2-CG 4.03Å; I175-E179 VanDerWaalsContact O-CB 3.31Å; I175-E179 WeakPolarHBondContact O-CB 3.19Å; I175-E179 PolarHBondContact O-N 3.27Å; E179-E182 PolarHBondContact O-N 2.97Å; E179-V183 WeakPolarHBondContact O-CG2 3.37Å; E179-V183 PolarHBondContact O-N 3.33Å; E179-L395 HydrophobicContact CG-CB 4.46Å; E179-L395 HydrophobicContact CG-CD2 4.2Å; E179-L395 WeakPolarHBondContact OE1-CB 3.43Å; E179-H396 PolarHBondContact OE1-N 3.44Å; E179-R412 WeakPolarHBondContact OE2-CD 3.46Å; E179-R412 WeakPolarHBondContact OE2-CG 3.38Å; E179-R412 IonicContact OE2-NE 3.05Å; E179-R412 PolarHBondContact OE2-NE 2.88Å; E179-L416 HydrophobicContact CB-CD1 4.27Å; E179-L416 HydrophobicContact CB-CD2 3.97Å; E179-L416 HydrophobicContact CB-CG 4.14Å
180	L	93.6	Very high	90.8	Very high	34 Å²	34	33 Å²	33	18%	0.178	16%	0.155	C	C	.	.	H	α-helix	trans	-63	-43.1	-179.1	-176.3	58.7	0	0	0	113.4	V176 E182 V183 I184 L204 V208 L416	V176-L180 HydrophobicContact CG1-CD2 4.28Å; V176-L180 WeakPolarHBondContact O-CB 3.03Å; V176-L180 PolarHBondContact O-N 2.93Å; L180-E182 VanDerWaalsContact C-N 3.29Å; L180-E182 PolarHBondContact O-N 3.49Å; L180-V183 PolarHBondContact O-N 3.38Å; L180-I184 HydrophobicContact CD1-CD1 4.3Å; L180-I184 HydrophobicContact CD1-CG1 4.36Å; L180-I184 HydrophobicContact CG-CD1 4.09Å; L180-I184 WeakPolarHBondContact O-CG1 3.36Å; L180-I184 PolarHBondContact O-N 2.94Å; L180-L204 HydrophobicContact CD2-CB 4.05Å; L180-L204 HydrophobicContact CD2-CD1 4.42Å; L180-L204 HydrophobicContact CG-CD1 4.17Å; L180-V208 HydrophobicContact CD2-CG2 3.48Å; L180-V208 VanDerWaalsContact CD2-CG2 3.48Å; L180-L416 HydrophobicContact CB-CD1 4.34Å; L180-L416 HydrophobicContact CB-CD2 4.41Å; L180-L416 HydrophobicContact CD1-CD1 4.27Å
181	P	91.6	Very high	89.6	Confident	7 Å²	7	40.5 Å²	40.5	5%	0.045	19%	0.19	C	C	.	.	H	α-helix	trans	-52.5	-45.6	170.6	-25	30.1	0	0	0	113.3	K177 V183 I184 R185 L199 L204	K177-P181 VanDerWaalsContact O-CD 3.25Å; K177-P181 WeakPolarHBondContact O-CD 3.27Å; K177-P181 VanDerWaalsContact O-CG 3.29Å; K177-P181 WeakPolarHBondContact O-CG 3.27Å; P181-V183 VanDerWaalsContact C-N 3.33Å; P181-V183 PolarHBondContact O-N 3.41Å; P181-I184 PolarHBondContact O-N 3.45Å; P181-R185 WeakPolarHBondContact O-CG 3.47Å; P181-R185 PolarHBondContact O-N 3.45Å; P181-L199 WeakPolarHBondContact CB-O 3.32Å; P181-L204 HydrophobicContact CB-CD1 4.36Å; P181-L204 HydrophobicContact CG-CD1 3.82Å
182	E	88.2	Confident	88.3	Confident	38 Å²	38	48.3 Å²	48.3	18%	0.178	23%	0.227	C	C	.	.	H	α-helix	trans	-68	-35.1	-176.9	-59.3	-53.2	149	0	0	112.2	E179 L180 R185 A186 T399	E179-E182 PolarHBondContact O-N 2.97Å; L180-E182 VanDerWaalsContact C-N 3.29Å; L180-E182 PolarHBondContact O-N 3.49Å; E182-R185 PolarHBondContact O-N 2.84Å; E182-R185 IonicContact OE1-CZ 3.61Å; E182-R185 IonicContact OE1-NH1 2.63Å; E182-R185 PolarHBondContact OE1-NH1 3.45Å; E182-R185 IonicContact OE2-NH1 2.62Å; E182-R185 PolarHBondContact OE2-NH1 3.02Å; E182-A186 WeakPolarHBondContact O-CB 3.23Å; E182-A186 PolarHBondContact O-N 3.2Å; E182-T399 HydrophobicContact CG-CG2 4.25Å
183	V	91	Very high	86.9	Confident	5 Å²	5	53 Å²	53	3%	0.03	25%	0.252	C	S	.	.	H	α-helix	trans	-63	-46	171.6	170.2	0	0	0	0	110.8	E179 L180 P181 R185 A186 F187 L409 R412 L413 L416	E179-V183 WeakPolarHBondContact O-CG2 3.37Å; E179-V183 PolarHBondContact O-N 3.33Å; L180-V183 PolarHBondContact O-N 3.38Å; P181-V183 VanDerWaalsContact C-N 3.33Å; P181-V183 PolarHBondContact O-N 3.41Å; V183-R185 PolarHBondContact O-N 3.04Å; V183-A186 PolarHBondContact O-N 3.26Å; V183-F187 HydrophobicContact CG1-CD2 3.71Å; V183-F187 HydrophobicContact CG1-CE2 3.6Å; V183-F187 VanDerWaalsContact O-CD2 3.23Å; V183-F187 WeakPolarHBondContact O-CD2 3.25Å; V183-F187 PolarHBondContact O-N 3.37Å; V183-L409 HydrophobicContact CB-CD1 4.24Å; V183-L409 HydrophobicContact CG1-CD1 3.99Å; V183-L409 HydrophobicContact CG2-CD1 4.08Å; V183-R412 HydrophobicContact CG2-CB 3.53Å; V183-R412 HydrophobicContact CG2-CG 4.39Å; V183-L413 HydrophobicContact CG1-CD2 3.61Å; V183-L413 HydrophobicContact CG1-CG 4.11Å; V183-L416 HydrophobicContact CB-CD1 4.34Å; V183-L416 HydrophobicContact CG2-CD1 3.67Å
184	I	90.6	Very high	85.5	Confident	37 Å²	37	56.1 Å²	56.1	19%	0.19	27%	0.274	C	S	.	.	H	α-helix	trans	-62.8	-43	178.4	-65.5	167.5	0	0	0	110.8	L180 P181 A186 F187 L188 Y198 L199 L204	L180-I184 HydrophobicContact CD1-CD1 4.3Å; L180-I184 HydrophobicContact CD1-CG1 4.36Å; L180-I184 HydrophobicContact CG-CD1 4.09Å; L180-I184 WeakPolarHBondContact O-CG1 3.36Å; L180-I184 PolarHBondContact O-N 2.94Å; P181-I184 PolarHBondContact O-N 3.45Å; I184-A186 VanDerWaalsContact C-N 3.33Å; I184-A186 PolarHBondContact O-N 3.48Å; I184-F187 PolarHBondContact O-N 2.99Å; I184-L188 HydrophobicContact CG2-CD1 3.7Å; I184-L188 HydrophobicContact CG2-CG 4.31Å; I184-L188 WeakPolarHBondContact O-CB 3.49Å; I184-L188 WeakPolarHBondContact O-CG 3.29Å; I184-L188 PolarHBondContact O-N 2.89Å; I184-Y198 HydrophobicContact CG2-CD2 4.03Å; I184-Y198 HydrophobicContact CG2-CE2 4.45Å; I184-L199 HydrophobicContact CB-CD2 4.18Å; I184-L199 HydrophobicContact CG2-CD2 3.77Å; I184-L204 HydrophobicContact CD1-CD1 3.75Å; I184-L204 HydrophobicContact CD1-CD2 3.9Å; I184-L204 HydrophobicContact CD1-CG 4.49Å
185	R	86.4	Confident	84.4	Confident	44 Å²	44	58.8 Å²	58.8	17%	0.166	30%	0.304	C	S	.	.	H	α-helix	trans	-60.3	-42.7	175.7	-71.6	-167.3	-168.5	126.1	6.7	112.3	P181 E182 V183 L188 H189 L190 N193 L199	P181-R185 WeakPolarHBondContact O-CG 3.47Å; P181-R185 PolarHBondContact O-N 3.45Å; E182-R185 PolarHBondContact O-N 2.84Å; E182-R185 IonicContact OE1-CZ 3.61Å; E182-R185 IonicContact OE1-NH1 2.63Å; E182-R185 PolarHBondContact OE1-NH1 3.45Å; E182-R185 IonicContact OE2-NH1 2.62Å; E182-R185 PolarHBondContact OE2-NH1 3.02Å; V183-R185 PolarHBondContact O-N 3.04Å; R185-L188 PolarHBondContact O-N 3.24Å; R185-H189 PolarHBondContact O-N 3.4Å; R185-L190 PolarHBondContact O-N 3.02Å; R185-L190 VanDerWaalsContact O-N 3.14Å; R185-N193 PolarHBondContact NH2-ND2 3.5Å; R185-N193 PolarHBondContact NH2-OD1 2.88Å; R185-L199 HydrophobicContact CG-CD1 4.11Å; R185-L199 HydrophobicContact CG-CD2 3.58Å; R185-L199 HydrophobicContact CG-CG 4.44Å
186	A	85.6	Confident	84	Confident	8 Å²	8	62.7 Å²	62.7	7%	0.066	32%	0.322	C	S	.	.	H	α-helix	trans	-64.4	-41.5	178.4	0	0	0	0	0	112	E182 V183 I184 H189 F404 L409	E182-A186 WeakPolarHBondContact O-CB 3.23Å; E182-A186 PolarHBondContact O-N 3.2Å; V183-A186 PolarHBondContact O-N 3.26Å; I184-A186 VanDerWaalsContact C-N 3.33Å; I184-A186 PolarHBondContact O-N 3.48Å; A186-H189 PolarHBondContact O-N 3Å; A186-F404 HydrophobicContact CB-CD1 4.47Å; A186-L409 HydrophobicContact CB-CD1 3.77Å; A186-L409 HydrophobicContact CB-CD2 4.18Å; A186-L409 HydrophobicContact CB-CG 4.5Å
187	F	87.4	Confident	83.5	Confident	122 Å²	122	69.9 Å²	69.9	54%	0.535	35%	0.349	S	S	.	.	H	α-helix	trans	-66.4	-40.8	176.1	-84.7	-67.8	0	0	0	113.1	V183 I184 H189 L409 L413	V183-F187 HydrophobicContact CG1-CD2 3.71Å; V183-F187 HydrophobicContact CG1-CE2 3.6Å; V183-F187 VanDerWaalsContact O-CD2 3.23Å; V183-F187 WeakPolarHBondContact O-CD2 3.25Å; V183-F187 PolarHBondContact O-N 3.37Å; I184-F187 PolarHBondContact O-N 2.99Å; F187-H189 VanDerWaalsContact C-N 3.29Å; F187-H189 PolarHBondContact O-N 3.34Å; F187-H189 PolarHBondContact O-ND1 3.3Å; F187-H189 VanDerWaalsContact O-ND1 3.16Å; F187-L409 HydrophobicContact CD2-CD1 4.49Å; F187-L409 HydrophobicContact CE1-CD2 4.44Å; F187-L409 HydrophobicContact CE2-CD1 4.24Å; F187-L409 HydrophobicContact CE2-CD2 4.39Å; F187-L409 HydrophobicContact CZ-CD2 4.28Å; F187-L413 HydrophobicContact CE2-CD1 3.89Å; F187-L413 HydrophobicContact CE2-CD2 4.18Å; F187-L413 HydrophobicContact CE2-CG 4.44Å; F187-L413 HydrophobicContact CZ-CD1 3.77Å
188	L	86.1	Confident	83.1	Confident	91 Å²	91	72.3 Å²	72.3	48%	0.476	36%	0.358	S	S	.	.	H	α-helix	trans	-83.5	-2.5	-179	-63.5	177.9	0	0	0	113.6	I184 R185 L190 Y198	I184-L188 HydrophobicContact CG2-CD1 3.7Å; I184-L188 HydrophobicContact CG2-CG 4.31Å; I184-L188 WeakPolarHBondContact O-CB 3.49Å; I184-L188 WeakPolarHBondContact O-CG 3.29Å; I184-L188 PolarHBondContact O-N 2.89Å; R185-L188 PolarHBondContact O-N 3.24Å; L188-L190 HydrophobicContact CB-CD1 3.77Å; L188-L190 HydrophobicContact CB-CG 3.68Å; L188-L190 HydrophobicContact CD1-CD1 3.88Å; L188-L190 PolarHBondContact O-N 3.46Å; L188-Y198 HydrophobicContact CD1-CD2 4.29Å; L188-Y198 HydrophobicContact CD1-CE2 3.68Å
189	H	81.6	Confident	83	Confident	147 Å²	147	69.1 Å²	69.1	68%	0.681	35%	0.346	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.2	41.4	-176.5	-62.7	72.5	0	0	0	112.8	R185 A186 F187	R185-H189 PolarHBondContact O-N 3.4Å; A186-H189 PolarHBondContact O-N 3Å; F187-H189 VanDerWaalsContact C-N 3.29Å; F187-H189 PolarHBondContact O-N 3.34Å; F187-H189 PolarHBondContact O-ND1 3.3Å; F187-H189 VanDerWaalsContact O-ND1 3.16Å
190	L	80.1	Confident	82.9	Confident	51 Å²	51	72 Å²	72	27%	0.267	36%	0.361	S	S	.	.			trans	-88.8	115.9	-179.8	-62.5	173.3	0	0	0	109.8	R185 L188 Y198 L199	R185-L190 PolarHBondContact O-N 3.02Å; R185-L190 VanDerWaalsContact O-N 3.14Å; L188-L190 HydrophobicContact CB-CD1 3.77Å; L188-L190 HydrophobicContact CB-CG 3.68Å; L188-L190 HydrophobicContact CD1-CD1 3.88Å; L188-L190 PolarHBondContact O-N 3.46Å; L190-Y198 HydrophobicContact CD1-CE2 4.13Å; L190-L199 HydrophobicContact CD1-CD1 4.09Å
191	E	69.6	Low	82.8	Confident	159 Å²	159	70.9 Å²	70.9	74%	0.743	36%	0.358	S	S	*	.			trans	-82.3	-29.1	178.4	-66.5	-170.1	156.3	0	0	113.1	F404	E191-F404 HydrophobicContact CG-CE2 4.21Å; E191-F404 HydrophobicContact CG-CZ 4.15Å
192	E	68.7	Low	83	Confident	164 Å²	164	73.1 Å²	73.1	77%	0.766	37%	0.37	S	S	*	.	S	Bend	trans	-110.6	146.8	-178	-72	-173.8	167.8	0	0	112.9	S194	E192-S194 PolarHBondContact O-N 2.97Å
193	N	65.3	Low	83.3	Confident	105 Å²	105	77.5 Å²	77.5	56%	0.561	39%	0.386	S	S	*	.			trans	-86.2	90.9	177.2	-160.3	25.3	0	0	0	109.4	R185 G195	R185-N193 PolarHBondContact NH2-ND2 3.5Å; R185-N193 PolarHBondContact NH2-OD1 2.88Å; N193-G195 PolarHBondContact O-N 2.98Å; N193-G195 VanDerWaalsContact O-N 3.09Å
194	S	66.7	Low	83.4	Confident	66 Å²	66	78 Å²	78	46%	0.462	39%	0.388	S	S	.	.			trans	-69.6	0.5	-178.6	44.2	0	0	0	0	114.6	E192 E196	E192-S194 PolarHBondContact O-N 2.97Å; S194-E196 PolarHBondContact O-N 3.37Å; S194-E196 WeakPolarHBondContact OG-CG 3.35Å
195	G	73.1	Confident	83.7	Confident	64 Å²	64	76.2 Å²	76.2	66%	0.66	38%	0.379	S	S	*	.			trans	71.9	12.8	-179.5	0	0	0	0	0	113.9	N193	N193-G195 PolarHBondContact O-N 2.98Å; N193-G195 VanDerWaalsContact O-N 3.09Å
196	E	84.5	Confident	84.2	Confident	82 Å²	82	76.5 Å²	76.5	38%	0.383	39%	0.385	S	S	.	.			trans	-65.8	146.7	-176	-64.9	-66.7	162.1	0	0	112.5	S194 Y198 L199 N200	S194-E196 PolarHBondContact O-N 3.37Å; S194-E196 WeakPolarHBondContact OG-CG 3.35Å; E196-Y198 HydrophobicContact CB-CD1 3.73Å; E196-Y198 HydrophobicContact CB-CE1 3.33Å; E196-Y198 HydrophobicContact CB-CE2 4.4Å; E196-Y198 HydrophobicContact CB-CG 4.41Å; E196-Y198 HydrophobicContact CG-CE1 3.71Å; E196-Y198 PolarHBondContact O-N 3.48Å; E196-Y198 VanDerWaalsContact O-N 3.15Å; E196-L199 PolarHBondContact O-N 3.19Å; E196-N200 PolarHBondContact O-N 2.94Å
197	W	85.9	Confident	84.6	Confident	154 Å²	154	81.7 Å²	81.7	58%	0.583	41%	0.407	S	S	*	.	G	3₁₀ helix	trans	-59.2	-31.2	-175.9	65.8	-88.9	0	0	0	113.2	L199 N200 Y203 F207	W197-L199 VanDerWaalsContact C-N 3.29Å; W197-L199 PolarHBondContact O-N 3.33Å; W197-N200 PolarHBondContact O-N 3.25Å; W197-Y203 HydrophobicContact CB-CD2 4.47Å; W197-F207 HydrophobicContact CE3-CE2 4.13Å; W197-F207 AromaticContact CZ3-CE2 3.99Å; W197-F207 HydrophobicContact CZ3-CE2 3.99Å
198	Y	86.1	Confident	85	Confident	65 Å²	65	76.8 Å²	76.8	26%	0.255	39%	0.387	S	S	.	.	G	3₁₀ helix	trans	-80.3	-5.7	179.7	65.1	-97.2	0	0	0	113.7	I184 L188 L190 E196 L204	I184-Y198 HydrophobicContact CG2-CD2 4.03Å; I184-Y198 HydrophobicContact CG2-CE2 4.45Å; L188-Y198 HydrophobicContact CD1-CD2 4.29Å; L188-Y198 HydrophobicContact CD1-CE2 3.68Å; L190-Y198 HydrophobicContact CD1-CE2 4.13Å; E196-Y198 HydrophobicContact CB-CD1 3.73Å; E196-Y198 HydrophobicContact CB-CE1 3.33Å; E196-Y198 HydrophobicContact CB-CE2 4.4Å; E196-Y198 HydrophobicContact CB-CG 4.41Å; E196-Y198 HydrophobicContact CG-CE1 3.71Å; E196-Y198 PolarHBondContact O-N 3.48Å; E196-Y198 VanDerWaalsContact O-N 3.15Å; Y198-L204 WeakPolarHBondContact O-CD1 3.43Å
199	L	88.1	Confident	85.5	Confident	8 Å²	8	72.5 Å²	72.5	4%	0.042	37%	0.365	C	S	.	.	G	3₁₀ helix	trans	-105.9	-3.8	170.8	-62.7	-179.5	0	0	0	112	P181 I184 R185 L190 E196 W197 G201	P181-L199 WeakPolarHBondContact CB-O 3.32Å; I184-L199 HydrophobicContact CB-CD2 4.18Å; I184-L199 HydrophobicContact CG2-CD2 3.77Å; R185-L199 HydrophobicContact CG-CD1 4.11Å; R185-L199 HydrophobicContact CG-CD2 3.58Å; R185-L199 HydrophobicContact CG-CG 4.44Å; L190-L199 HydrophobicContact CD1-CD1 4.09Å; E196-L199 PolarHBondContact O-N 3.19Å; W197-L199 VanDerWaalsContact C-N 3.29Å; W197-L199 PolarHBondContact O-N 3.33Å; L199-G201 PolarHBondContact O-N 3.2Å
200	N	91.4	Very high	86.2	Confident	60 Å²	60	70.6 Å²	70.6	32%	0.321	36%	0.358	S	S	.	.			trans	-84.1	108.9	178.1	-174.7	-29	0	0	0	110.1	E196 W197 N202 Y203 L204	E196-N200 PolarHBondContact O-N 2.94Å; W197-N200 PolarHBondContact O-N 3.25Å; N200-N202 PolarHBondContact O-N 3.24Å; N200-N202 VanDerWaalsContact O-N 3.13Å; N200-N202 WeakPolarHBondContact OD1-CB 3.44Å; N200-N202 PolarHBondContact OD1-N 3.11Å; N200-Y203 HydrophobicContact CB-CD2 3.71Å; N200-Y203 HydrophobicContact CB-CE2 4.32Å; N200-Y203 PolarHBondContact O-N 2.8Å; N200-L204 PolarHBondContact O-N 3.26Å; N200-L204 VanDerWaalsContact O-N 3.11Å
201	G	91.8	Very high	86.9	Confident	11 Å²	11	70.7 Å²	70.7	11%	0.113	37%	0.371	C	S	.	.	H	α-helix	trans	-52.8	-33.4	-179.8	0	0	0	0	0	114.7	K177 L199 Y203 L204 V205	K177-G201 WeakPolarHBondContact O-CA 3.39Å; L199-G201 PolarHBondContact O-N 3.2Å; G201-Y203 PolarHBondContact O-N 3.49Å; G201-L204 PolarHBondContact O-N 3.43Å; G201-V205 WeakPolarHBondContact O-CG1 3.45Å; G201-V205 PolarHBondContact O-N 2.83Å
202	N	94.1	Very high	88	Confident	55 Å²	55	67.1 Å²	67.1	29%	0.294	36%	0.357	S	S	.	.	H	α-helix	trans	-67.6	-35.1	179.8	-65.9	-27.3	0	0	0	112.2	K177 N200 V205 V206 I465	K177-N202 WeakPolarHBondContact CD-OD1 3.31Å; K177-N202 WeakPolarHBondContact CE-OD1 3.48Å; K177-N202 PolarHBondContact NZ-OD1 2.91Å; N200-N202 PolarHBondContact O-N 3.24Å; N200-N202 VanDerWaalsContact O-N 3.13Å; N200-N202 WeakPolarHBondContact OD1-CB 3.44Å; N200-N202 PolarHBondContact OD1-N 3.11Å; N202-V205 WeakPolarHBondContact O-CG1 3.2Å; N202-V206 WeakPolarHBondContact O-CG2 3.3Å; N202-I465 HydrophobicContact CB-CG1 4.31Å
203	Y	94.4	Very high	89.2	Confident	130 Å²	130	59.3 Å²	59.3	51%	0.51	32%	0.32	S	S	.	.	H	α-helix	trans	-78	-42.4	174.9	-65.9	-54.7	0	0	0	111	W197 N200 G201 V205 V206 F207	W197-Y203 HydrophobicContact CB-CD2 4.47Å; N200-Y203 HydrophobicContact CB-CD2 3.71Å; N200-Y203 HydrophobicContact CB-CE2 4.32Å; N200-Y203 PolarHBondContact O-N 2.8Å; G201-Y203 PolarHBondContact O-N 3.49Å; Y203-V205 PolarHBondContact O-N 3.33Å; Y203-V206 PolarHBondContact O-N 2.91Å; Y203-F207 WeakPolarHBondContact O-CD2 3.48Å; Y203-F207 PolarHBondContact O-N 2.95Å
204	L	94.8	Very high	90.6	Very high	15 Å²	15	55.6 Å²	55.6	8%	0.079	30%	0.3	C	S	.	.	H	α-helix	trans	-60.5	-43.3	-178.6	-70.7	175.8	0	0	0	112.9	L180 P181 I184 Y198 N200 G201 V206 F207 V208	L180-L204 HydrophobicContact CD2-CB 4.05Å; L180-L204 HydrophobicContact CD2-CD1 4.42Å; L180-L204 HydrophobicContact CG-CD1 4.17Å; P181-L204 HydrophobicContact CB-CD1 4.36Å; P181-L204 HydrophobicContact CG-CD1 3.82Å; I184-L204 HydrophobicContact CD1-CD1 3.75Å; I184-L204 HydrophobicContact CD1-CD2 3.9Å; I184-L204 HydrophobicContact CD1-CG 4.49Å; Y198-L204 WeakPolarHBondContact O-CD1 3.43Å; N200-L204 PolarHBondContact O-N 3.26Å; N200-L204 VanDerWaalsContact O-N 3.11Å; G201-L204 PolarHBondContact O-N 3.43Å; L204-V206 VanDerWaalsContact C-N 3.26Å; L204-V206 PolarHBondContact O-N 3.04Å; L204-F207 PolarHBondContact O-N 3.37Å; L204-V208 WeakPolarHBondContact O-CG2 3.49Å; L204-V208 PolarHBondContact O-N 3.36Å
205	V	96.3	Very high	91.8	Very high	0 Å²	0	55.4 Å²	55.4	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-61.3	-36.6	178	69.3	0	0	0	0	111.8	L173 V176 K177 G201 N202 Y203 S209 N461	L173-V205 HydrophobicContact CB-CG2 3.95Å; L173-V205 HydrophobicContact CD2-CG2 4.03Å; L173-V205 HydrophobicContact CG-CG2 4.48Å; L173-V205 WeakPolarHBondContact O-CG2 3.32Å; V176-V205 HydrophobicContact CB-CG2 4.46Å; V176-V205 HydrophobicContact CG1-CG2 4.35Å; K177-V205 HydrophobicContact CB-CB 4.09Å; K177-V205 HydrophobicContact CB-CG1 4.38Å; K177-V205 HydrophobicContact CB-CG2 4.42Å; G201-V205 WeakPolarHBondContact O-CG1 3.45Å; G201-V205 PolarHBondContact O-N 2.83Å; N202-V205 WeakPolarHBondContact O-CG1 3.2Å; Y203-V205 PolarHBondContact O-N 3.33Å; V205-S209 WeakPolarHBondContact O-CB 3.24Å; V205-S209 PolarHBondContact O-N 3.45Å; V205-S209 PolarHBondContact O-OG 3.33Å; V205-N461 PolarHBondContact O-OD1 3Å
206	V	96.3	Very high	92.6	Very high	49 Å²	49	55.2 Å²	55.2	30%	0.297	28%	0.281	S	S	.	.	H	α-helix	trans	-69.2	-43.4	175.7	175.7	0	0	0	0	110.8	N202 Y203 L204 S209 I210 I465	N202-V206 WeakPolarHBondContact O-CG2 3.3Å; Y203-V206 PolarHBondContact O-N 2.91Å; L204-V206 VanDerWaalsContact C-N 3.26Å; L204-V206 PolarHBondContact O-N 3.04Å; V206-S209 WeakPolarHBondContact O-CB 3.12Å; V206-S209 PolarHBondContact O-N 3.15Å; V206-I210 HydrophobicContact CG1-CD1 3.83Å; V206-I210 WeakPolarHBondContact O-CG1 3.45Å; V206-I210 PolarHBondContact O-N 2.68Å; V206-I465 HydrophobicContact CG2-CD1 4.36Å
207	F	95.4	Very high	92.8	Very high	117 Å²	117	51.6 Å²	51.6	51%	0.513	27%	0.265	S	S	.	.	H	α-helix	trans	-63.3	-45.3	177.3	-72.6	-55.8	0	0	0	112.6	W197 Y203 L204 S209 I210 G211	W197-F207 HydrophobicContact CE3-CE2 4.13Å; W197-F207 AromaticContact CZ3-CE2 3.99Å; W197-F207 HydrophobicContact CZ3-CE2 3.99Å; Y203-F207 WeakPolarHBondContact O-CD2 3.48Å; Y203-F207 PolarHBondContact O-N 2.95Å; L204-F207 PolarHBondContact O-N 3.37Å; F207-S209 VanDerWaalsContact C-N 3.29Å; F207-S209 PolarHBondContact O-N 3.25Å; F207-I210 PolarHBondContact O-N 3.15Å; F207-G211 PolarHBondContact O-N 2.97Å
208	V	96	Very high	92.9	Very high	19 Å²	19	46.1 Å²	46.1	12%	0.115	25%	0.247	C	C	.	.	H	α-helix	trans	-62.4	-40.5	174.8	171.7	0	0	0	0	110.8	V176 L180 L204 I210 I212 I213 T420	V176-V208 HydrophobicContact CG1-CB 4.16Å; V176-V208 HydrophobicContact CG1-CG1 4.13Å; V176-V208 HydrophobicContact CG1-CG2 4.17Å; L180-V208 HydrophobicContact CD2-CG2 3.48Å; L180-V208 VanDerWaalsContact CD2-CG2 3.48Å; L204-V208 WeakPolarHBondContact O-CG2 3.49Å; L204-V208 PolarHBondContact O-N 3.36Å; V208-I210 PolarHBondContact O-N 3.43Å; V208-I212 HydrophobicContact CG1-CD1 4.42Å; V208-I212 WeakPolarHBondContact O-CB 3.37Å; V208-I212 PolarHBondContact O-N 3.47Å; V208-I213 HydrophobicContact CG1-CD1 4.09Å; V208-I213 HydrophobicContact CG1-CG1 4.27Å; V208-I213 PolarHBondContact O-N 3.45Å; V208-I213 VanDerWaalsContact O-N 3.1Å; V208-T420 HydrophobicContact CG1-CG2 4.25Å
209	S	96.1	Very high	92.7	Very high	2 Å²	2	47.5 Å²	47.5	1%	0.014	26%	0.258	C	S	.	.	I	π-helix	trans	-59	-48.3	177.2	-69.6	0	0	0	0	112	V205 V206 F207 L214 L457 N461	V205-S209 WeakPolarHBondContact O-CB 3.24Å; V205-S209 PolarHBondContact O-N 3.45Å; V205-S209 PolarHBondContact O-OG 3.33Å; V206-S209 WeakPolarHBondContact O-CB 3.12Å; V206-S209 PolarHBondContact O-N 3.15Å; F207-S209 VanDerWaalsContact C-N 3.29Å; F207-S209 PolarHBondContact O-N 3.25Å; S209-L214 VanDerWaalsContact O-CB 3.3Å; S209-L214 WeakPolarHBondContact O-CB 3.23Å; S209-L214 PolarHBondContact O-N 3.01Å; S209-L457 WeakPolarHBondContact O-CD2 3.26Å; S209-N461 WeakPolarHBondContact CB-ND2 3.45Å; S209-N461 PolarHBondContact OG-ND2 3.37Å; S209-N461 PolarHBondContact OG-OD1 3.44Å
210	I	95.6	Very high	91.8	Very high	106 Å²	106	51.9 Å²	51.9	54%	0.544	28%	0.277	S	S	.	.	I	π-helix	trans	-76.8	-41.2	-178.3	-64.4	170.4	0	0	0	111.7	V206 F207 V208 P215	V206-I210 HydrophobicContact CG1-CD1 3.83Å; V206-I210 WeakPolarHBondContact O-CG1 3.45Å; V206-I210 PolarHBondContact O-N 2.68Å; F207-I210 PolarHBondContact O-N 3.15Å; V208-I210 PolarHBondContact O-N 3.43Å; I210-P215 VanDerWaalsContact O-CD 3.23Å; I210-P215 WeakPolarHBondContact O-CD 3.46Å
211	G	94.6	Very high	90.3	Very high	53 Å²	53	55.5 Å²	55.5	55%	0.546	30%	0.296	S	S	.	.	I	π-helix	trans	-83.3	-28	-171.3	0	0	0	0	0	115	F207	F207-G211 PolarHBondContact O-N 2.97Å
212	I	93.8	Very high	88.7	Confident	85 Å²	85	56.9 Å²	56.9	44%	0.436	30%	0.301	S	S	.	.	I	π-helix	trans	-122.4	-57.2	-174	-56.7	178.6	0	0	0	110.6	V208 P215 L216 T420	V208-I212 HydrophobicContact CG1-CD1 4.42Å; V208-I212 WeakPolarHBondContact O-CB 3.37Å; V208-I212 PolarHBondContact O-N 3.47Å; I212-P215 WeakPolarHBondContact O-CD 3.36Å; I212-L216 HydrophobicContact CG2-CD1 3.83Å; I212-L216 WeakPolarHBondContact O-CB 3.2Å; I212-L216 VanDerWaalsContact O-CG 3.26Å; I212-L216 WeakPolarHBondContact O-CG 3.22Å; I212-L216 PolarHBondContact O-N 2.84Å; I212-T420 HydrophobicContact CG2-CG2 3.82Å
213	I	94.2	Very high	86.9	Confident	0 Å²	0	57.3 Å²	57.3	0%	0	32%	0.318	C	S	.	.	I	π-helix	trans	-68.6	-47.4	-169.8	-63.1	175	0	0	0	111.4	L173 V208 L216 S217 T420 V423 P424 L457	L173-I213 HydrophobicContact CD2-CD1 3.57Å; V208-I213 HydrophobicContact CG1-CD1 4.09Å; V208-I213 HydrophobicContact CG1-CG1 4.27Å; V208-I213 PolarHBondContact O-N 3.45Å; V208-I213 VanDerWaalsContact O-N 3.1Å; I213-L216 PolarHBondContact O-N 2.92Å; I213-S217 WeakPolarHBondContact O-CB 3.46Å; I213-S217 PolarHBondContact O-N 3.32Å; I213-T420 HydrophobicContact CD1-CG2 4.45Å; I213-T420 HydrophobicContact CG1-CG2 3.96Å; I213-V423 HydrophobicContact CD1-CB 4.23Å; I213-V423 HydrophobicContact CD1-CG1 4.19Å; I213-V423 HydrophobicContact CD1-CG2 4.33Å; I213-V423 HydrophobicContact CG2-CB 4.06Å; I213-V423 HydrophobicContact CG2-CG1 3.4Å; I213-V423 VanDerWaalsContact CG2-CG1 3.4Å; I213-P424 HydrophobicContact CG2-CG 4.41Å; I213-L457 HydrophobicContact CB-CD2 4.38Å; I213-L457 HydrophobicContact CG2-CD1 4.03Å; I213-L457 HydrophobicContact CG2-CD2 4.08Å
214	L	93.4	Very high	85.4	Confident	26 Å²	26	59.5 Å²	59.5	14%	0.136	33%	0.326	C	S	.	.	H	α-helix	trans	-60.5	-51.7	-178.7	180	65.9	0	0	0	111.2	S209 L216 S217 L218 L450 A453 A454 L457	S209-L214 VanDerWaalsContact O-CB 3.3Å; S209-L214 WeakPolarHBondContact O-CB 3.23Å; S209-L214 PolarHBondContact O-N 3.01Å; L214-L216 VanDerWaalsContact C-N 3.34Å; L214-L216 PolarHBondContact O-N 3.41Å; L214-S217 PolarHBondContact O-N 3.01Å; L214-S217 VanDerWaalsContact O-N 3.09Å; L214-S217 PolarHBondContact O-OG 2.92Å; L214-L218 HydrophobicContact CG-CD1 4.46Å; L214-L218 VanDerWaalsContact O-CG 3.32Å; L214-L218 WeakPolarHBondContact O-CG 3.25Å; L214-L218 PolarHBondContact O-N 3.49Å; L214-L450 HydrophobicContact CD1-CD1 4.36Å; L214-L450 HydrophobicContact CD2-CD1 4.39Å; L214-A453 HydrophobicContact CD1-CB 4.02Å; L214-A454 HydrophobicContact CD1-CB 4.36Å; L214-L457 HydrophobicContact CB-CD2 3.92Å
215	P	92.6	Very high	83.7	Confident	63 Å²	63	60.5 Å²	60.5	41%	0.409	33%	0.332	S	S	.	.	H	α-helix	trans	-54	-46	174.6	-28.1	34.4	0	0	0	113.7	I210 I212 S217 L218	I210-P215 VanDerWaalsContact O-CD 3.23Å; I210-P215 WeakPolarHBondContact O-CD 3.46Å; I212-P215 WeakPolarHBondContact O-CD 3.36Å; P215-S217 VanDerWaalsContact C-N 3.29Å; P215-S217 PolarHBondContact O-N 2.77Å; P215-L218 PolarHBondContact O-N 3.01Å
216	L	89.6	Confident	82.3	Confident	59 Å²	59	60.8 Å²	60.8	31%	0.309	34%	0.335	S	S	.	.	H	α-helix	trans	-62.8	-36.8	178.2	-71.1	173.8	0	0	0	112	I212 I213 L214 L218 L219 L421 P424	I212-L216 HydrophobicContact CG2-CD1 3.83Å; I212-L216 WeakPolarHBondContact O-CB 3.2Å; I212-L216 VanDerWaalsContact O-CG 3.26Å; I212-L216 WeakPolarHBondContact O-CG 3.22Å; I212-L216 PolarHBondContact O-N 2.84Å; I213-L216 PolarHBondContact O-N 2.92Å; L214-L216 VanDerWaalsContact C-N 3.34Å; L214-L216 PolarHBondContact O-N 3.41Å; L216-L218 VanDerWaalsContact C-N 3.27Å; L216-L218 PolarHBondContact O-N 3.17Å; L216-L219 HydrophobicContact CD2-CD1 4.21Å; L216-L219 WeakPolarHBondContact O-CB 3.17Å; L216-L219 WeakPolarHBondContact O-CG 3.28Å; L216-L219 PolarHBondContact O-N 2.91Å; L216-L421 HydrophobicContact CD1-CD2 4.34Å; L216-P424 HydrophobicContact CB-CB 4.25Å; L216-P424 HydrophobicContact CB-CG 3.69Å; L216-P424 HydrophobicContact CD1-CG 4.38Å
217	S	87.9	Confident	81.5	Confident	6 Å²	6	66.1 Å²	66.1	4%	0.042	35%	0.351	C	S	.	.	H	α-helix	trans	-70.5	-19.8	178.8	78.9	0	0	0	0	114	I213 L214 P215 L219 R431	I213-S217 WeakPolarHBondContact O-CB 3.46Å; I213-S217 PolarHBondContact O-N 3.32Å; L214-S217 PolarHBondContact O-N 3.01Å; L214-S217 VanDerWaalsContact O-N 3.09Å; L214-S217 PolarHBondContact O-OG 2.92Å; P215-S217 VanDerWaalsContact C-N 3.29Å; P215-S217 PolarHBondContact O-N 2.77Å; S217-L219 VanDerWaalsContact C-N 3.31Å; S217-R431 PolarHBondContact O-NH1 3.3Å
218	L	87.9	Confident	81	Confident	39 Å²	39	62.5 Å²	62.5	20%	0.204	34%	0.338	C	S	.	.	T	Hydrogen-bonded Turn	trans	-83.4	-6.3	178.5	-62.3	169.5	0	0	0	113.2	L214 P215 L216 K220 L450 A453	L214-L218 HydrophobicContact CG-CD1 4.46Å; L214-L218 VanDerWaalsContact O-CG 3.32Å; L214-L218 WeakPolarHBondContact O-CG 3.25Å; L214-L218 PolarHBondContact O-N 3.49Å; P215-L218 PolarHBondContact O-N 3.01Å; L216-L218 VanDerWaalsContact C-N 3.27Å; L216-L218 PolarHBondContact O-N 3.17Å; L218-K220 PolarHBondContact O-N 3.4Å; L218-L450 HydrophobicContact CD1-CD1 3.57Å; L218-L450 HydrophobicContact CD2-CB 4.13Å; L218-L450 HydrophobicContact CD2-CD1 3.71Å; L218-L450 HydrophobicContact CG-CD1 4.23Å; L218-A453 HydrophobicContact CD2-CB 4.39Å
219	L	83.1	Confident	80.5	Confident	94 Å²	94	61.8 Å²	61.8	49%	0.492	33%	0.334	S	S	.	.			trans	-63.9	124.8	176.1	-63.8	175.6	0	0	0	109.7	L216 S217	L216-L219 HydrophobicContact CD2-CD1 4.21Å; L216-L219 WeakPolarHBondContact O-CB 3.17Å; L216-L219 WeakPolarHBondContact O-CG 3.28Å; L216-L219 PolarHBondContact O-N 2.91Å; S217-L219 VanDerWaalsContact C-N 3.31Å
220	K	68.3	Low	80.2	Confident	101 Å²	101	62.6 Å²	62.6	44%	0.439	34%	0.343	S	S	.	.	S	Bend	trans	-69.3	-37.4	-176.8	-79.1	180	162.9	174.7	0	113.2	L218 W446	L218-K220 PolarHBondContact O-N 3.4Å; K220-W446 HydrophobicContact CD-CH2 3.77Å; K220-W446 HydrophobicContact CD-CZ2 3.72Å; K220-W446 VanDerWaalsContact CE-CE2 3.47Å; K220-W446 VanDerWaalsContact CE-CH2 3.47Å; K220-W446 HydrophobicContact CG-CH2 3.81Å; K220-W446 HydrophobicContact CG-CZ2 4.28Å; K220-W446 HydrophobicContact CG-CZ3 4.37Å
221	N	59.7	Low	79.9	Confident	136 Å²	136	62.7 Å²	62.7	73%	0.727	34%	0.34	S	S	*	.			trans	-115.8	108	-175.6	-63.2	-29.4	0	0	0	108.1	G223	N221-G223 PolarHBondContact O-N 3.24Å; N221-G223 VanDerWaalsContact O-N 3.16Å
222	L	59.1	Low	79.6	Confident	40 Å²	40	60.2 Å²	60.2	21%	0.209	31%	0.314	C	S	.	.			trans	-81.3	28.1	170.3	-67.7	174.4	0	0	0	111.1	Y224 L225 F428	L222-Y224 PolarHBondContact O-N 3.32Å; L222-L225 HydrophobicContact CB-CB 4.39Å; L222-L225 HydrophobicContact CB-CD1 3.74Å; L222-L225 HydrophobicContact CB-CD2 3.95Å; L222-L225 HydrophobicContact CB-CG 4.24Å; L222-L225 HydrophobicContact CD1-CD1 4.09Å; L222-L225 HydrophobicContact CD1-CD2 3.98Å; L222-L225 HydrophobicContact CD2-CD1 3.68Å; L222-L225 HydrophobicContact CG-CD1 4.02Å; L222-L225 HydrophobicContact CG-CD2 4.5Å; L222-L225 VanDerWaalsContact O-CB 3.26Å; L222-L225 WeakPolarHBondContact O-CB 3.22Å; L222-L225 PolarHBondContact O-N 2.92Å; L222-F428 HydrophobicContact CD1-CB 3.86Å; L222-F428 HydrophobicContact CD1-CD2 3.54Å; L222-F428 HydrophobicContact CD1-CE2 4.26Å; L222-F428 HydrophobicContact CD1-CG 3.76Å; L222-F428 HydrophobicContact CG-CD2 4.48Å
223	G	56.7	Low	79.4	Confident	63 Å²	63	57.2 Å²	57.2	65%	0.649	30%	0.298	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.1	-10.1	-178.8	0	0	0	0	0	114.7	N221	N221-G223 PolarHBondContact O-N 3.24Å; N221-G223 VanDerWaalsContact O-N 3.16Å
224	Y	61.8	Low	79.3	Confident	176 Å²	176	60.9 Å²	60.9	69%	0.69	32%	0.324	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.4	1.8	173.6	-60.8	-78.5	0	0	0	114.2	L222 G226 Y227 T228	L222-Y224 PolarHBondContact O-N 3.32Å; Y224-G226 PolarHBondContact O-N 2.84Å; Y224-Y227 HydrophobicContact CD1-CD2 4.34Å; Y224-Y227 PolarHBondContact O-N 3.24Å; Y224-T228 PolarHBondContact O-N 2.95Å
225	L	59.3	Low	79.3	Confident	37 Å²	37	60.2 Å²	60.2	19%	0.194	32%	0.322	C	S	.	.	H	α-helix	trans	-57.3	-34.6	-175.9	-127.8	52.1	0	0	0	113.2	N86 L222 Y227 T228 S229 I425	N86-L225 PolarHBondContact OD1-O 3.37Å; L222-L225 HydrophobicContact CB-CB 4.39Å; L222-L225 HydrophobicContact CB-CD1 3.74Å; L222-L225 HydrophobicContact CB-CD2 3.95Å; L222-L225 HydrophobicContact CB-CG 4.24Å; L222-L225 HydrophobicContact CD1-CD1 4.09Å; L222-L225 HydrophobicContact CD1-CD2 3.98Å; L222-L225 HydrophobicContact CD2-CD1 3.68Å; L222-L225 HydrophobicContact CG-CD1 4.02Å; L222-L225 HydrophobicContact CG-CD2 4.5Å; L222-L225 VanDerWaalsContact O-CB 3.26Å; L222-L225 WeakPolarHBondContact O-CB 3.22Å; L222-L225 PolarHBondContact O-N 2.92Å; L225-Y227 VanDerWaalsContact C-N 3.28Å; L225-Y227 PolarHBondContact O-N 3.19Å; L225-T228 WeakPolarHBondContact CA-OG1 3.41Å; L225-T228 PolarHBondContact O-N 3.26Å; L225-T228 PolarHBondContact O-OG1 2.89Å; L225-S229 VanDerWaalsContact O-CB 3.29Å; L225-S229 WeakPolarHBondContact O-CB 3.36Å; L225-S229 PolarHBondContact O-N 3.45Å; L225-S229 PolarHBondContact O-OG 2.87Å; L225-I425 HydrophobicContact CD1-CD1 3.92Å; L225-I425 HydrophobicContact CD1-CG1 3.59Å; L225-I425 HydrophobicContact CD2-CG1 4.32Å; L225-I425 HydrophobicContact CD2-CG2 3.91Å; L225-I425 HydrophobicContact CG-CD1 3.89Å; L225-I425 HydrophobicContact CG-CG1 3.92Å; L225-I425 HydrophobicContact CG-CG2 4.32Å
226	G	67.4	Low	79.2	Confident	6 Å²	6	57.5 Å²	57.5	6%	0.062	30%	0.303	C	S	.	.	H	α-helix	trans	-56.8	-42.5	175.3	0	0	0	0	0	113.3	M82 N86 Y224 G230	M82-G226 VanDerWaalsContact CG-CA 3.5Å; N86-G226 VanDerWaalsContact OD1-CA 3.31Å; N86-G226 WeakPolarHBondContact OD1-CA 3.49Å; Y224-G226 PolarHBondContact O-N 2.84Å; G226-G230 PolarHBondContact O-N 3.1Å; G226-G230 VanDerWaalsContact O-N 3.13Å
227	Y	79.8	Confident	79.4	Confident	161 Å²	161	57.9 Å²	57.9	63%	0.631	31%	0.308	S	S	*	.	H	α-helix	trans	-76.5	-39.8	-178.3	-61.6	-76.1	0	0	0	111.6	M82 Y224 L225 G230 F231	M82-Y227 HydrophobicContact CE-CD2 4.4Å; M82-Y227 HydrophobicContact CE-CE1 4.48Å; M82-Y227 HydrophobicContact CE-CE2 3.98Å; Y224-Y227 HydrophobicContact CD1-CD2 4.34Å; Y224-Y227 PolarHBondContact O-N 3.24Å; L225-Y227 VanDerWaalsContact C-N 3.28Å; L225-Y227 PolarHBondContact O-N 3.19Å; Y227-G230 PolarHBondContact O-N 3.32Å; Y227-F231 PolarHBondContact O-N 3.48Å
228	T	83.9	Confident	79.7	Confident	41 Å²	41	61.2 Å²	61.2	25%	0.252	32%	0.322	S	S	.	.	H	α-helix	trans	-65.9	-38.4	176.1	57.1	0	0	0	0	111.8	Y224 L225 F231 S232	Y224-T228 PolarHBondContact O-N 2.95Å; L225-T228 WeakPolarHBondContact CA-OG1 3.41Å; L225-T228 PolarHBondContact O-N 3.26Å; L225-T228 PolarHBondContact O-OG1 2.89Å; T228-F231 PolarHBondContact O-N 3.27Å; T228-S232 WeakPolarHBondContact O-CB 3.29Å; T228-S232 PolarHBondContact O-N 3.2Å
229	S	85.8	Confident	79.9	Confident	3 Å²	3	59.4 Å²	59.4	2%	0.021	31%	0.313	C	S	.	.	H	α-helix	trans	-64.3	-41.4	174	-63.6	0	0	0	0	112	N86 L225 S232 L233	N86-S229 VanDerWaalsContact OD1-CB 3.31Å; N86-S229 WeakPolarHBondContact OD1-CB 3.47Å; N86-S229 PolarHBondContact OD1-OG 2.93Å; N86-S229 VanDerWaalsContact OD1-OG 3.04Å; L225-S229 VanDerWaalsContact O-CB 3.29Å; L225-S229 WeakPolarHBondContact O-CB 3.36Å; L225-S229 PolarHBondContact O-N 3.45Å; L225-S229 PolarHBondContact O-OG 2.87Å; S229-S232 PolarHBondContact O-N 2.71Å; S229-L233 WeakPolarHBondContact O-CB 3.35Å; S229-L233 PolarHBondContact O-N 3.42Å
230	G	88.8	Confident	80.5	Confident	20 Å²	20	55.6 Å²	55.6	21%	0.206	29%	0.293	C	S	.	.	H	α-helix	trans	-63.1	-41.7	174.5	0	0	0	0	0	112.8	G226 Y227 L233 S234	G226-G230 PolarHBondContact O-N 3.1Å; G226-G230 VanDerWaalsContact O-N 3.13Å; Y227-G230 PolarHBondContact O-N 3.32Å; G230-L233 PolarHBondContact O-N 3.25Å; G230-S234 PolarHBondContact O-N 2.96Å
231	F	89.8	Confident	81.7	Confident	108 Å²	108	54.9 Å²	54.9	47%	0.474	30%	0.296	S	S	.	.	H	α-helix	trans	-63.7	-47	174.7	179.1	-99.9	0	0	0	112.1	Y227 T228 L233 S234 C235 T417 L421	Y227-F231 PolarHBondContact O-N 3.48Å; T228-F231 PolarHBondContact O-N 3.27Å; F231-L233 VanDerWaalsContact C-N 3.31Å; F231-L233 PolarHBondContact O-N 3Å; F231-S234 WeakPolarHBondContact O-CB 3.26Å; F231-S234 PolarHBondContact O-N 3.04Å; F231-S234 VanDerWaalsContact O-N 3.11Å; F231-C235 PolarHBondContact O-N 3.08Å; F231-C235 PolarHBondContact O-SG 3.18Å; F231-T417 HydrophobicContact CE1-CG2 3.76Å; F231-T417 HydrophobicContact CZ-CG2 4.46Å; F231-L421 HydrophobicContact CD1-CD1 3.77Å; F231-L421 HydrophobicContact CE1-CD1 4.08Å
232	S	88.9	Confident	83.3	Confident	1 Å²	1	49 Å²	49	1%	0.007	27%	0.266	C	S	.	.	H	α-helix	trans	-54.8	-46.2	174.7	178.8	0	0	0	0	111.8	N89 T228 S229 S234 C235 M236	N89-S232 VanDerWaalsContact OD1-CB 3.26Å; N89-S232 WeakPolarHBondContact OD1-CB 3.21Å; N89-S232 PolarHBondContact OD1-OG 2.98Å; T228-S232 WeakPolarHBondContact O-CB 3.29Å; T228-S232 PolarHBondContact O-N 3.2Å; S229-S232 PolarHBondContact O-N 2.71Å; S232-S234 VanDerWaalsContact C-N 3.35Å; S232-S234 PolarHBondContact O-N 3.37Å; S232-C235 WeakPolarHBondContact O-CB 3.21Å; S232-C235 PolarHBondContact O-N 3.42Å; S232-M236 WeakPolarHBondContact O-CG 3.49Å; S232-M236 PolarHBondContact O-N 3.25Å
233	L	89.4	Confident	84.9	Confident	21 Å²	21	47.3 Å²	47.3	11%	0.11	26%	0.257	C	S	.	.	H	α-helix	trans	-62.7	-41.2	177.1	-176.4	64.5	0	0	0	111.9	F85 M92 S229 G230 F231 C235 M236 V237 M371 M374	F85-L233 HydrophobicContact CD1-CD2 3.48Å; F85-L233 VanDerWaalsContact CD1-CD2 3.48Å; F85-L233 HydrophobicContact CE1-CD2 3.82Å; M92-L233 HydrophobicContact SD-CD1 3.7Å; S229-L233 WeakPolarHBondContact O-CB 3.35Å; S229-L233 PolarHBondContact O-N 3.42Å; G230-L233 PolarHBondContact O-N 3.25Å; F231-L233 VanDerWaalsContact C-N 3.31Å; F231-L233 PolarHBondContact O-N 3Å; L233-C235 PolarHBondContact O-N 3.3Å; L233-M236 PolarHBondContact O-N 3.44Å; L233-V237 WeakPolarHBondContact O-CG2 3.36Å; L233-V237 PolarHBondContact O-N 3.36Å; L233-M371 HydrophobicContact CD1-CE 3.87Å; L233-M374 HydrophobicContact CD1-CE 3.81Å; L233-M374 HydrophobicContact CD1-SD 4.36Å
234	S	92.3	Very high	86.6	Confident	78 Å²	78	46.8 Å²	46.8	55%	0.545	24%	0.238	S	C	.	.	H	α-helix	trans	-61.5	-42.4	175.8	-172.6	0	0	0	0	112.3	G230 F231 S232 M236 V237 F238	G230-S234 PolarHBondContact O-N 2.96Å; F231-S234 WeakPolarHBondContact O-CB 3.26Å; F231-S234 PolarHBondContact O-N 3.04Å; F231-S234 VanDerWaalsContact O-N 3.11Å; S232-S234 VanDerWaalsContact C-N 3.35Å; S232-S234 PolarHBondContact O-N 3.37Å; S234-M236 PolarHBondContact O-N 3.43Å; S234-V237 PolarHBondContact O-N 3.39Å; S234-F238 PolarHBondContact O-N 3.06Å
235	C	92.4	Very high	88	Confident	12 Å²	12	43.5 Å²	43.5	8%	0.081	23%	0.225	C	C	.	.	H	α-helix	trans	-58.1	-36.8	174.8	-72	0	0	0	0	111.9	F231 S232 L233 F238 F239 A414 A418	F231-C235 PolarHBondContact O-N 3.08Å; F231-C235 PolarHBondContact O-SG 3.18Å; S232-C235 WeakPolarHBondContact O-CB 3.21Å; S232-C235 PolarHBondContact O-N 3.42Å; L233-C235 PolarHBondContact O-N 3.3Å; C235-F238 WeakPolarHBondContact O-CB 3.38Å; C235-F238 PolarHBondContact O-N 2.93Å; C235-F239 PolarHBondContact O-N 3.45Å; C235-A414 HydrophobicContact CB-CB 3.92Å; C235-A418 HydrophobicContact CB-CB 4.03Å
236	M	90.9	Very high	89.3	Confident	5 Å²	5	42.4 Å²	42.4	3%	0.025	22%	0.219	C	C	.	.	H	α-helix	trans	-81.7	-30.3	-178	-62.7	-72	-170.5	0	0	113.8	M92 I96 S232 L233 S234 F238 F239 L240 V415 A418 V419	M92-M236 HydrophobicContact CE-CB 3.02Å; M92-M236 HydrophobicContact CE-CG 3.52Å; M92-M236 HydrophobicContact CE-SD 4.29Å; M92-M236 HydrophobicContact CG-CG 4.16Å; M92-M236 HydrophobicContact SD-CB 3.31Å; M92-M236 WeakPolarHBondContact SD-CB 3.28Å; M92-M236 HydrophobicContact SD-CG 3.38Å; M92-M236 WeakPolarHBondContact SD-CG 3.48Å; I96-M236 HydrophobicContact CG2-SD 4.46Å; S232-M236 WeakPolarHBondContact O-CG 3.49Å; S232-M236 PolarHBondContact O-N 3.25Å; L233-M236 PolarHBondContact O-N 3.44Å; S234-M236 PolarHBondContact O-N 3.43Å; M236-F238 VanDerWaalsContact C-N 3.28Å; M236-F239 WeakPolarHBondContact O-CB 3.22Å; M236-F239 PolarHBondContact O-N 3.29Å; M236-L240 PolarHBondContact O-N 2.9Å; M236-V415 HydrophobicContact CE-CG1 4.44Å; M236-V415 HydrophobicContact SD-CG2 4.21Å; M236-A418 HydrophobicContact CE-CB 3.91Å; M236-V419 HydrophobicContact CE-CG1 4.27Å
237	V	93.9	Very high	90.3	Very high	67 Å²	67	44.4 Å²	44.4	41%	0.406	23%	0.226	S	C	.	.	H	α-helix	trans	-61.3	-41.9	166.2	172.5	0	0	0	0	109.9	L233 S234 L240 V241 M374	L233-V237 WeakPolarHBondContact O-CG2 3.36Å; L233-V237 PolarHBondContact O-N 3.36Å; S234-V237 PolarHBondContact O-N 3.39Å; V237-L240 PolarHBondContact O-N 3.41Å; V237-V241 WeakPolarHBondContact O-CG2 3.37Å; V237-V241 PolarHBondContact O-N 2.83Å; V237-M374 HydrophobicContact CG2-SD 3.91Å
238	F	94.4	Very high	90.6	Very high	77 Å²	77	41.6 Å²	41.6	34%	0.338	23%	0.226	S	C	.	.	H	α-helix	trans	-60.4	-46.2	174.2	172.4	-110.1	0	0	0	112.2	S234 C235 M236 L240 V241 V242 L410 V411 A414	S234-F238 PolarHBondContact O-N 3.06Å; C235-F238 WeakPolarHBondContact O-CB 3.38Å; C235-F238 PolarHBondContact O-N 2.93Å; M236-F238 VanDerWaalsContact C-N 3.28Å; F238-L240 VanDerWaalsContact C-N 3.33Å; F238-L240 PolarHBondContact O-N 3.19Å; F238-V241 PolarHBondContact O-N 2.9Å; F238-V242 HydrophobicContact CD2-CG2 4.16Å; F238-V242 HydrophobicContact CE1-CG2 4.29Å; F238-V242 HydrophobicContact CE2-CG2 3.68Å; F238-V242 HydrophobicContact CZ-CG2 3.76Å; F238-V242 WeakPolarHBondContact O-CG2 3.44Å; F238-V242 PolarHBondContact O-N 3.01Å; F238-L410 HydrophobicContact CE1-CB 4.06Å; F238-L410 HydrophobicContact CZ-CB 4.07Å; F238-V411 HydrophobicContact CD1-CG2 4.14Å; F238-V411 HydrophobicContact CE1-CB 4.45Å; F238-V411 HydrophobicContact CE1-CG2 3.65Å; F238-V411 HydrophobicContact CZ-CG2 4.2Å; F238-A414 HydrophobicContact CD1-CB 4.02Å; F238-A414 HydrophobicContact CE1-CB 4.47Å
239	F	92.9	Very high	90.4	Very high	1 Å²	1	41.5 Å²	41.5	0%	0.004	22%	0.222	C	C	.	.	H	α-helix	trans	-52.1	-49.3	171.6	159.1	-108.6	0	0	0	112.1	I96 L97 C235 M236 V241 V242 I243 L394 L395 V411 V415	I96-F239 HydrophobicContact CD1-CD1 4.2Å; I96-F239 HydrophobicContact CD1-CE1 3.91Å; I96-F239 HydrophobicContact CG1-CE1 4.07Å; I96-F239 HydrophobicContact CG2-CE1 4.43Å; L97-F239 HydrophobicContact CD2-CE1 4.07Å; L97-F239 HydrophobicContact CD2-CE2 4.06Å; L97-F239 HydrophobicContact CD2-CZ 3.5Å; L97-F239 VanDerWaalsContact CD2-CZ 3.5Å; C235-F239 PolarHBondContact O-N 3.45Å; M236-F239 WeakPolarHBondContact O-CB 3.22Å; M236-F239 PolarHBondContact O-N 3.29Å; F239-V241 PolarHBondContact O-N 3.34Å; F239-V242 PolarHBondContact O-N 2.89Å; F239-I243 HydrophobicContact CD1-CD1 3.85Å; F239-I243 HydrophobicContact CD2-CD1 3.66Å; F239-I243 HydrophobicContact CD2-CG1 4.02Å; F239-I243 HydrophobicContact CE1-CD1 3.4Å; F239-I243 HydrophobicContact CE2-CD1 3.19Å; F239-I243 HydrophobicContact CE2-CG1 3.74Å; F239-I243 HydrophobicContact CG-CD1 4.01Å; F239-I243 HydrophobicContact CZ-CD1 3.09Å; F239-I243 HydrophobicContact CZ-CG1 4.15Å; F239-I243 WeakPolarHBondContact O-CG1 3.28Å; F239-I243 PolarHBondContact O-N 3.33Å; F239-L394 HydrophobicContact CE2-CD2 4.41Å; F239-L394 HydrophobicContact CZ-CD2 4.01Å; F239-L395 HydrophobicContact CD2-CD1 4.05Å; F239-L395 HydrophobicContact CE2-CD1 3.34Å; F239-L395 HydrophobicContact CZ-CD1 4.09Å; F239-V411 HydrophobicContact CB-CG1 4.19Å; F239-V411 HydrophobicContact CD2-CG1 3.56Å; F239-V411 HydrophobicContact CE2-CG1 4.46Å; F239-V411 HydrophobicContact CG-CG1 4.36Å; F239-V415 HydrophobicContact CB-CG2 4.23Å; F239-V415 HydrophobicContact CD2-CG2 4.25Å; F239-V415 HydrophobicContact CG-CG2 4.29Å
240	L	94.2	Very high	90	Very high	14 Å²	14	41.8 Å²	41.8	7%	0.073	22%	0.224	C	C	.	.	H	α-helix	trans	-60	-46	178.9	175.9	61	0	0	0	112.2	M236 V237 F238 V242 I243 I244 M374 L377	M236-L240 PolarHBondContact O-N 2.9Å; V237-L240 PolarHBondContact O-N 3.41Å; F238-L240 VanDerWaalsContact C-N 3.33Å; F238-L240 PolarHBondContact O-N 3.19Å; L240-V242 VanDerWaalsContact C-N 3.3Å; L240-V242 PolarHBondContact O-N 3.21Å; L240-I243 PolarHBondContact O-N 3.23Å; L240-I244 HydrophobicContact CD1-CD1 4.03Å; L240-I244 HydrophobicContact CD1-CG1 4.3Å; L240-I244 HydrophobicContact CG-CD1 4.03Å; L240-I244 VanDerWaalsContact O-CG1 3.31Å; L240-I244 WeakPolarHBondContact O-CG1 3.45Å; L240-I244 PolarHBondContact O-N 2.93Å; L240-M374 HydrophobicContact CD2-CB 4.34Å; L240-M374 HydrophobicContact CD2-CG 4.18Å; L240-L377 HydrophobicContact CD1-CB 3.75Å; L240-L377 HydrophobicContact CD2-CB 4.16Å; L240-L377 HydrophobicContact CD2-CD1 4.12Å
241	V	95	Very high	89.4	Confident	86 Å²	86	44.9 Å²	44.9	52%	0.521	24%	0.24	S	C	.	.	H	α-helix	trans	-59	-43.6	178	170.7	0	0	0	0	110.8	V237 F238 F239 I244 Y245	V237-V241 WeakPolarHBondContact O-CG2 3.37Å; V237-V241 PolarHBondContact O-N 2.83Å; F238-V241 PolarHBondContact O-N 2.9Å; F239-V241 PolarHBondContact O-N 3.34Å; V241-I244 PolarHBondContact O-N 2.74Å; V241-Y245 WeakPolarHBondContact O-CB 3.46Å; V241-Y245 PolarHBondContact O-N 3.24Å
242	V	92.9	Very high	88.7	Confident	13 Å²	13	41.8 Å²	41.8	8%	0.079	23%	0.232	C	C	.	.	H	α-helix	trans	-68.3	-38.6	179.5	175.1	0	0	0	0	111.9	F238 F239 L240 I244 Y245 K246 M407 V411	F238-V242 HydrophobicContact CD2-CG2 4.16Å; F238-V242 HydrophobicContact CE1-CG2 4.29Å; F238-V242 HydrophobicContact CE2-CG2 3.68Å; F238-V242 HydrophobicContact CZ-CG2 3.76Å; F238-V242 WeakPolarHBondContact O-CG2 3.44Å; F238-V242 PolarHBondContact O-N 3.01Å; F239-V242 PolarHBondContact O-N 2.89Å; L240-V242 VanDerWaalsContact C-N 3.3Å; L240-V242 PolarHBondContact O-N 3.21Å; V242-I244 VanDerWaalsContact C-N 3.34Å; V242-I244 PolarHBondContact O-N 3.27Å; V242-Y245 PolarHBondContact O-N 2.93Å; V242-K246 HydrophobicContact CG1-CG 4.04Å; V242-K246 WeakPolarHBondContact O-CB 3.37Å; V242-K246 VanDerWaalsContact O-CG 3.3Å; V242-K246 WeakPolarHBondContact O-CG 3.46Å; V242-K246 PolarHBondContact O-N 3.23Å; V242-M407 HydrophobicContact CG1-CB 4.47Å; V242-V411 HydrophobicContact CB-CG2 3.5Å; V242-V411 HydrophobicContact CG1-CG2 3.57Å; V242-V411 HydrophobicContact CG2-CG2 3.58Å
243	I	91.7	Very high	88	Confident	4 Å²	4	43.5 Å²	43.5	2%	0.021	24%	0.243	C	C	.	.	H	α-helix	trans	-59.3	-47.4	174.2	-66.3	162	0	0	0	110.8	F239 L240 Y245 K246 K247 F381 L394 F398	F239-I243 HydrophobicContact CD1-CD1 3.85Å; F239-I243 HydrophobicContact CD2-CD1 3.66Å; F239-I243 HydrophobicContact CD2-CG1 4.02Å; F239-I243 HydrophobicContact CE1-CD1 3.4Å; F239-I243 HydrophobicContact CE2-CD1 3.19Å; F239-I243 HydrophobicContact CE2-CG1 3.74Å; F239-I243 HydrophobicContact CG-CD1 4.01Å; F239-I243 HydrophobicContact CZ-CD1 3.09Å; F239-I243 HydrophobicContact CZ-CG1 4.15Å; F239-I243 WeakPolarHBondContact O-CG1 3.28Å; F239-I243 PolarHBondContact O-N 3.33Å; L240-I243 PolarHBondContact O-N 3.23Å; I243-Y245 VanDerWaalsContact C-N 3.32Å; I243-Y245 PolarHBondContact O-N 3.45Å; I243-K246 PolarHBondContact O-N 3.43Å; I243-K247 PolarHBondContact O-N 2.83Å; I243-F381 HydrophobicContact CG2-CB 3.85Å; I243-L394 HydrophobicContact CD1-CD2 3.84Å; I243-L394 HydrophobicContact CG1-CD2 4.39Å; I243-F398 HydrophobicContact CG1-CE2 4.49Å
244	I	93.4	Very high	87.3	Confident	51 Å²	51	42.7 Å²	42.7	26%	0.262	24%	0.238	S	C	.	.	H	α-helix	trans	-60.1	-47.7	179	-65.3	168.8	0	0	0	109.6	L240 V241 V242 K246 K247 T248 F381	L240-I244 HydrophobicContact CD1-CD1 4.03Å; L240-I244 HydrophobicContact CD1-CG1 4.3Å; L240-I244 HydrophobicContact CG-CD1 4.03Å; L240-I244 VanDerWaalsContact O-CG1 3.31Å; L240-I244 WeakPolarHBondContact O-CG1 3.45Å; L240-I244 PolarHBondContact O-N 2.93Å; V241-I244 PolarHBondContact O-N 2.74Å; V242-I244 VanDerWaalsContact C-N 3.34Å; V242-I244 PolarHBondContact O-N 3.27Å; I244-K246 PolarHBondContact O-N 3.02Å; I244-K247 PolarHBondContact O-N 3.46Å; I244-T248 PolarHBondContact O-N 3.39Å; I244-F381 HydrophobicContact CB-CG 4.49Å; I244-F381 HydrophobicContact CD1-CD2 4.16Å; I244-F381 HydrophobicContact CD1-CE2 4.18Å; I244-F381 HydrophobicContact CG1-CB 4.26Å; I244-F381 HydrophobicContact CG1-CD1 4.28Å; I244-F381 HydrophobicContact CG1-CD2 3.56Å; I244-F381 HydrophobicContact CG1-CE2 3.9Å; I244-F381 HydrophobicContact CG1-CG 3.78Å; I244-F381 HydrophobicContact CG1-CZ 4.41Å; I244-F381 HydrophobicContact CG2-CD1 4.41Å; I244-F381 HydrophobicContact CG2-CE1 4.19Å; I244-F381 HydrophobicContact CG2-CZ 4.27Å
245	Y	91.4	Very high	86.2	Confident	108 Å²	108	43.8 Å²	43.8	42%	0.424	24%	0.244	S	C	.	.	H	α-helix	trans	-59.1	-47.6	177.1	176.7	-103.7	0	0	0	111.8	V241 V242 I243 K247 T248 Q249	V241-Y245 WeakPolarHBondContact O-CB 3.46Å; V241-Y245 PolarHBondContact O-N 3.24Å; V242-Y245 PolarHBondContact O-N 2.93Å; I243-Y245 VanDerWaalsContact C-N 3.32Å; I243-Y245 PolarHBondContact O-N 3.45Å; Y245-K247 VanDerWaalsContact C-N 3.34Å; Y245-K247 PolarHBondContact O-N 2.99Å; Y245-T248 PolarHBondContact O-N 3.32Å; Y245-T248 PolarHBondContact O-OG1 3.17Å; Y245-Q249 HydrophobicContact CE1-CG 4.08Å; Y245-Q249 HydrophobicContact CE2-CG 4.44Å; Y245-Q249 PolarHBondContact O-N 2.82Å; Y245-Q249 PolarHBondContact OH-NE2 3.15Å
246	K	86.7	Confident	85.2	Confident	13 Å²	13	45 Å²	45	6%	0.057	25%	0.247	C	C	.	.	H	α-helix	trans	-62.5	-39.5	179.2	-74.1	-63.7	-174.2	-175	0	111.9	V242 I243 I244 T248 Q249 L250 F398 D405	V242-K246 HydrophobicContact CG1-CG 4.04Å; V242-K246 WeakPolarHBondContact O-CB 3.37Å; V242-K246 VanDerWaalsContact O-CG 3.3Å; V242-K246 WeakPolarHBondContact O-CG 3.46Å; V242-K246 PolarHBondContact O-N 3.23Å; I243-K246 PolarHBondContact O-N 3.43Å; I244-K246 PolarHBondContact O-N 3.02Å; K246-T248 PolarHBondContact O-N 3.2Å; K246-T248 VanDerWaalsContact O-N 3.17Å; K246-Q249 PolarHBondContact O-N 2.9Å; K246-L250 HydrophobicContact CB-CD1 3.93Å; K246-L250 VanDerWaalsContact O-CD1 3.23Å; K246-L250 WeakPolarHBondContact O-CD1 3.14Å; K246-L250 PolarHBondContact O-N 3.31Å; K246-F398 HydrophobicContact CB-CE1 4Å; K246-F398 HydrophobicContact CB-CZ 4.46Å; K246-D405 WeakPolarHBondContact CE-OD1 3.45Å; K246-D405 IonicContact NZ-OD1 2.94Å; K246-D405 PolarHBondContact NZ-OD1 3.36Å; K246-D405 IonicContact NZ-OD2 2.61Å; K246-D405 PolarHBondContact NZ-OD2 3.39Å
247	K	87.8	Confident	84.3	Confident	49 Å²	49	44.7 Å²	44.7	21%	0.213	25%	0.246	C	C	.	.	H	α-helix	trans	-56.5	-33.1	173.9	174.5	63.3	-159.8	86.5	0	113.1	I243 I244 Y245 Q249 F381 L384 T385	I243-K247 PolarHBondContact O-N 2.83Å; I244-K247 PolarHBondContact O-N 3.46Å; Y245-K247 VanDerWaalsContact C-N 3.34Å; Y245-K247 PolarHBondContact O-N 2.99Å; K247-Q249 VanDerWaalsContact C-N 3.32Å; K247-F381 HydrophobicContact CB-CD1 4.14Å; K247-F381 HydrophobicContact CG-CD1 3.98Å; K247-L384 HydrophobicContact CD-CB 3.97Å; K247-L384 WeakPolarHBondContact CD-O 3.47Å; K247-L384 WeakPolarHBondContact CE-O 3.44Å; K247-T385 WeakPolarHBondContact CD-OG1 3.33Å
248	T	85.1	Confident	82.8	Confident	101 Å²	101	46 Å²	46	62%	0.62	24%	0.244	S	C	*	.	H	α-helix	trans	-74.9	-22	177.1	67.8	0	0	0	0	113.5	I244 Y245 K246	I244-T248 PolarHBondContact O-N 3.39Å; Y245-T248 PolarHBondContact O-N 3.32Å; Y245-T248 PolarHBondContact O-OG1 3.17Å; K246-T248 PolarHBondContact O-N 3.2Å; K246-T248 VanDerWaalsContact O-N 3.17Å
249	Q	80.7	Confident	80.9	Confident	39 Å²	39	46.5 Å²	46.5	18%	0.182	26%	0.257	C	S	.	.	H	α-helix	trans	-93	-31.2	-178.4	-67.4	-67.5	-15	0	0	112.8	Y245 K246 K247 P251 F284	Y245-Q249 HydrophobicContact CE1-CG 4.08Å; Y245-Q249 HydrophobicContact CE2-CG 4.44Å; Y245-Q249 PolarHBondContact O-N 2.82Å; Y245-Q249 PolarHBondContact OH-NE2 3.15Å; K246-Q249 PolarHBondContact O-N 2.9Å; K247-Q249 VanDerWaalsContact C-N 3.32Å; Q249-P251 WeakPolarHBondContact O-CD 3.42Å; Q249-F284 PolarHBondContact OE1-O 3.28Å
250	L	78.3	Confident	79	Confident	10 Å²	10	49.8 Å²	49.8	5%	0.052	28%	0.281	C	S	.	.			trans	-81.5	112.5	-177.4	-80.8	133.1	0	0	0	111	K246 L254 T385 F398 V401 Y402	K246-L250 HydrophobicContact CB-CD1 3.93Å; K246-L250 VanDerWaalsContact O-CD1 3.23Å; K246-L250 WeakPolarHBondContact O-CD1 3.14Å; K246-L250 PolarHBondContact O-N 3.31Å; L250-L254 HydrophobicContact CB-CD2 4.39Å; L250-L254 HydrophobicContact CD2-CD1 4.11Å; L250-L254 HydrophobicContact CD2-CD2 3.38Å; L250-L254 HydrophobicContact CD2-CG 4.42Å; L250-L254 HydrophobicContact CG-CD2 4.5Å; L250-T385 HydrophobicContact CD1-CG2 3.86Å; L250-F398 HydrophobicContact CD1-CE1 4.05Å; L250-V401 HydrophobicContact CD2-CG1 3.88Å; L250-Y402 HydrophobicContact CD1-CE2 4Å; L250-Y402 HydrophobicContact CD2-CE2 3.79Å; L250-Y402 HydrophobicContact CG-CE2 4.02Å
251	P	75.2	Confident	76.7	Confident	84 Å²	84	54.3 Å²	54.3	55%	0.545	31%	0.305	S	S	.	.			trans	-70.3	151.5	168.2	32.1	-34.2	0	0	0	109.7	Q249 L254	Q249-P251 WeakPolarHBondContact O-CD 3.42Å; P251-L254 WeakPolarHBondContact O-CD2 3.42Å
252	C	74.8	Confident	74.1	Confident	44 Å²	44	55.8 Å²	55.8	30%	0.297	31%	0.309	S	S	.	.	S	Bend	trans	-115	137.3	170.1	-168.9	0	0	0	0	107.6	C317 Y387	C252-C317 HydrophobicContact CB-CB 3.87Å; C252-C317 WeakPolarHBondContact CB-SG 3.45Å; C252-C317 VanDerWaalsContact SG-CA 3.56Å; C252-C317 WeakPolarHBondContact SG-CB 3.36Å; C252-C317 CovalentContact SG-SG 2.03Å; C252-C317 PolarHBondContact SG-SG 2.88Å; C252-Y387 HydrophobicContact CB-CE2 4.35Å; C252-Y387 VanDerWaalsContact SG-CE2 3.56Å
253	P	73.5	Confident	71.6	Confident	37 Å²	37	60 Å²	60	24%	0.24	34%	0.339	C	S	.	.	S	Bend	cis	-79	153.4	4.4	29.5	-34.5	0	0	0	114.8	Y258 D313 C317	P253-Y258 HydrophobicContact CB-CE2 4.17Å; P253-Y258 HydrophobicContact CG-CE2 3.95Å; P253-Y258 WeakPolarHBondContact CG-OH 3.47Å; P253-D313 HydrophobicContact CG-CB 4.29Å; P253-C317 VanDerWaalsContact CA-SG 3.52Å
254	L	75.5	Confident	69.1	Low	4 Å²	4	65.3 Å²	65.3	2%	0.021	37%	0.372	C	S	.	.			trans	-88.5	146.6	179.7	-67.5	170.8	0	0	0	111.8	L250 P251 F256 M257 F386 V401	L250-L254 HydrophobicContact CB-CD2 4.39Å; L250-L254 HydrophobicContact CD2-CD1 4.11Å; L250-L254 HydrophobicContact CD2-CD2 3.38Å; L250-L254 HydrophobicContact CD2-CG 4.42Å; L250-L254 HydrophobicContact CG-CD2 4.5Å; P251-L254 WeakPolarHBondContact O-CD2 3.42Å; L254-F256 VanDerWaalsContact C-N 3.29Å; L254-F256 HydrophobicContact CB-CD1 3.85Å; L254-F256 HydrophobicContact CB-CE1 3.63Å; L254-F256 HydrophobicContact CD1-CE1 3.62Å; L254-F256 HydrophobicContact CD1-CZ 4.31Å; L254-F256 HydrophobicContact CG-CE1 4.25Å; L254-F256 PolarHBondContact O-N 3.04Å; L254-F256 VanDerWaalsContact O-N 3.11Å; L254-M257 HydrophobicContact CB-CE 4.42Å; L254-M257 HydrophobicContact CB-CG 4.11Å; L254-M257 HydrophobicContact CB-SD 4.34Å; L254-M257 HydrophobicContact CD1-CE 4.23Å; L254-M257 WeakPolarHBondContact O-CB 3.3Å; L254-M257 PolarHBondContact O-N 3.18Å; L254-F386 HydrophobicContact CD1-CD1 3.77Å; L254-F386 HydrophobicContact CD1-CE1 3.95Å; L254-V401 HydrophobicContact CD1-CG2 4.26Å
255	P	68.6	Low	66.1	Low	101 Å²	101	68.3 Å²	68.3	66%	0.656	39%	0.389	S	S	*	.	H	α-helix	trans	-55.4	-35.1	-174.4	-28.3	34.7	0	0	0	115.5	M257	P255-M257 VanDerWaalsContact C-N 3.27Å; P255-M257 PolarHBondContact O-N 2.65Å
256	F	72.6	Confident	63.6	Low	36 Å²	36	70 Å²	70	16%	0.158	41%	0.405	C	S	.	.	H	α-helix	trans	-73.7	-17	179.3	77.6	-90.9	0	0	0	113.4	L254 Y258 S259 S260 F386 F389 V401	L254-F256 VanDerWaalsContact C-N 3.29Å; L254-F256 HydrophobicContact CB-CD1 3.85Å; L254-F256 HydrophobicContact CB-CE1 3.63Å; L254-F256 HydrophobicContact CD1-CE1 3.62Å; L254-F256 HydrophobicContact CD1-CZ 4.31Å; L254-F256 HydrophobicContact CG-CE1 4.25Å; L254-F256 PolarHBondContact O-N 3.04Å; L254-F256 VanDerWaalsContact O-N 3.11Å; F256-Y258 VanDerWaalsContact C-N 3.3Å; F256-S259 PolarHBondContact O-N 3.09Å; F256-S259 PolarHBondContact O-OG 3.42Å; F256-S260 PolarHBondContact O-OG 3.31Å; F256-F386 HydrophobicContact CE1-CD1 4.34Å; F256-F386 HydrophobicContact CZ-CD1 4.11Å; F256-F389 HydrophobicContact CE2-CB 4.02Å; F256-F389 HydrophobicContact CE2-CD1 4.47Å; F256-F389 HydrophobicContact CE2-CG 4.31Å; F256-F389 HydrophobicContact CZ-CB 4.3Å; F256-V401 HydrophobicContact CD1-CG2 3.72Å; F256-V401 HydrophobicContact CE1-CG2 3.46Å; F256-V401 VanDerWaalsContact CE1-CG2 3.46Å
257	M	70.9	Confident	61.2	Low	0 Å²	0	73.4 Å²	73.4	0%	0	43%	0.43	C	S	.	.	H	α-helix	trans	-70.7	-32	179	-59.2	-174.9	167	0	0	111	L254 P255 S260 M316 F386 F389	L254-M257 HydrophobicContact CB-CE 4.42Å; L254-M257 HydrophobicContact CB-CG 4.11Å; L254-M257 HydrophobicContact CB-SD 4.34Å; L254-M257 HydrophobicContact CD1-CE 4.23Å; L254-M257 WeakPolarHBondContact O-CB 3.3Å; L254-M257 PolarHBondContact O-N 3.18Å; P255-M257 VanDerWaalsContact C-N 3.27Å; P255-M257 PolarHBondContact O-N 2.65Å; M257-S260 PolarHBondContact O-N 3.31Å; M257-M316 HydrophobicContact CB-CE 3.3Å; M257-M316 HydrophobicContact CG-CE 4.33Å; M257-M316 HydrophobicContact SD-CE 4.26Å; M257-F386 VanDerWaalsContact CE-O 3.25Å; M257-F386 WeakPolarHBondContact CE-O 3.45Å; M257-F389 HydrophobicContact CB-CD2 4.46Å; M257-F389 HydrophobicContact CB-CE2 3.99Å; M257-F389 HydrophobicContact CB-CZ 4.09Å; M257-F389 HydrophobicContact CE-CB 4.34Å; M257-F389 HydrophobicContact CE-CD2 3.5Å; M257-F389 HydrophobicContact CE-CE2 4.17Å; M257-F389 HydrophobicContact CE-CG 4.23Å; M257-F389 HydrophobicContact CG-CD2 3.79Å; M257-F389 HydrophobicContact CG-CE2 3.81Å; M257-F389 HydrophobicContact CG-CG 4.26Å; M257-F389 HydrophobicContact CG-CZ 4.3Å; M257-F389 HydrophobicContact SD-CD2 3.71Å; M257-F389 HydrophobicContact SD-CE2 3.74Å
258	Y	63.3	Low	58.8	Low	93 Å²	93	75.6 Å²	75.6	37%	0.365	45%	0.445	S	S	.	.	H	α-helix	trans	-65	-38.1	173.8	-68.6	-75.6	0	0	0	113.1	P253 F256 S260 N261 L262 D313	P253-Y258 HydrophobicContact CB-CE2 4.17Å; P253-Y258 HydrophobicContact CG-CE2 3.95Å; P253-Y258 WeakPolarHBondContact CG-OH 3.47Å; F256-Y258 VanDerWaalsContact C-N 3.3Å; Y258-S260 PolarHBondContact O-N 3.04Å; Y258-N261 PolarHBondContact O-N 2.64Å; Y258-L262 PolarHBondContact O-N 3.25Å; Y258-D313 WeakPolarHBondContact CE1-OD1 3.32Å; Y258-D313 PolarHBondContact OH-OD1 3.32Å; Y258-D313 PolarHBondContact OH-OD2 3.27Å
259	S	54.4	Low	56.9	Low	88 Å²	88	74.9 Å²	74.9	62%	0.615	44%	0.436	S	S	*	.	H	α-helix	trans	-66.8	-21	177.7	48.9	0	0	0	0	113.6	F256	F256-S259 PolarHBondContact O-N 3.09Å; F256-S259 PolarHBondContact O-OG 3.42Å
260	S	52	Low	54.7	Low	71 Å²	71	77.2 Å²	77.2	50%	0.497	46%	0.456	S	S	.	.	H	α-helix	trans	-81	-23.5	180	-50.1	0	0	0	0	112.5	F256 M257 Y258	F256-S260 PolarHBondContact O-OG 3.31Å; M257-S260 PolarHBondContact O-N 3.31Å; Y258-S260 PolarHBondContact O-N 3.04Å
261	N	45.9	Very low	52.6	Low	108 Å²	108	86 Å²	86	58%	0.578	49%	0.489	S	S	*	.	H	α-helix	trans	-98.3	-12.9	-177.8	-75.1	-11.3	0	0	0	113.4	Y258	Y258-N261 PolarHBondContact O-N 2.64Å
262	L	41.8	Very low	51	Low	117 Å²	117	88 Å²	88	61%	0.613	50%	0.495	S	S	*	.			trans	-98.7	96.3	-175.8	-163.1	70.8	0	0	0	112.1	Y258	Y258-L262 PolarHBondContact O-N 3.25Å
263	S	40.4	Very low	49.3	Very low	102 Å²	102	92.2 Å²	92.2	71%	0.713	51%	0.505	S	S	*	.			trans	-71.7	123.7	155.2	54.9	0	0	0	0	109.4
264	T	39.4	Very low	47.3	Very low	115 Å²	115	93.9 Å²	93.9	71%	0.706	52%	0.522	S	S	*	.	S	Bend	trans	69.2	103.7	166	50	0	0	0	0	119.8
265	N	30.6	Very low	45.6	Very low	115 Å²	115	100.4 Å²	100.4	62%	0.615	56%	0.556	S	S	*	*				167.3	128.1	106.6	-96.5	-9.6	0	0	0	110.8	S267	N265-S267 PolarHBondContact O-N 2.98Å
266	D	37	Very low	44.4	Very low	143 Å²	143	103.7 Å²	103.7	77%	0.765	56%	0.556	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.2	-10.7	-168.9	-130.7	-3.1	0	0	0	115.2
267	S	36.9	Very low	42.4	Very low	84 Å²	84	109.8 Å²	109.8	59%	0.587	58%	0.584	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.5	-22.7	-171.7	52.2	0	0	0	0	115.3	N265	N265-S267 PolarHBondContact O-N 2.98Å
268	D	38.5	Very low	40.3	Very low	96 Å²	96	117.6 Å²	117.6	51%	0.513	63%	0.626	S	S	.	*	T	Hydrogen-bonded Turn	trans	-88	-17.8	178.6	-72.3	-40.1	0	0	0	112.8	S270 R271 L272	D268-S270 PolarHBondContact O-N 3.25Å; D268-R271 PolarHBondContact O-N 2.94Å; D268-L272 PolarHBondContact O-N 3.22Å
269	I	44.1	Very low	38.9	Very low	86 Å²	86	119.4 Å²	119.4	44%	0.441	64%	0.639	S	S	.	*	H	α-helix	trans	-65.3	-37.6	176.8	-64.8	175	0	0	0	111.2	R271 L272 Y273	I269-R271 VanDerWaalsContact C-N 3.3Å; I269-R271 PolarHBondContact O-N 2.91Å; I269-L272 PolarHBondContact O-N 2.94Å; I269-Y273 HydrophobicContact CG2-CD2 3.89Å; I269-Y273 HydrophobicContact CG2-CE2 4.16Å; I269-Y273 PolarHBondContact O-N 3.43Å
270	S	33.9	Very low	37.8	Very low	87 Å²	87	120.7 Å²	120.7	61%	0.608	65%	0.648	S	S	*	*	H	α-helix	trans	-66.5	-27.8	177	-70.7	0	0	0	0	113.6	D268 A274	D268-S270 PolarHBondContact O-N 3.25Å; S270-A274 WeakPolarHBondContact O-CB 3.24Å; S270-A274 PolarHBondContact O-N 2.89Å
271	R	34.4	Very low	36.9	Very low	196 Å²	196	125.9 Å²	125.9	74%	0.74	67%	0.665	S	S	*	*	H	α-helix	trans	-76.5	-35.6	177.3	-77	-173.4	174.8	-178.4	0.3	112.6	D268 I269 A274 L275	D268-R271 PolarHBondContact O-N 2.94Å; I269-R271 VanDerWaalsContact C-N 3.3Å; I269-R271 PolarHBondContact O-N 2.91Å; R271-A274 PolarHBondContact O-N 3.48Å; R271-L275 PolarHBondContact O-N 3.4Å
272	L	41.6	Very low	36.3	Very low	126 Å²	126	126.7 Å²	126.7	66%	0.66	67%	0.669	S	S	*	*	H	α-helix	trans	-70.8	-35.6	171.6	-99.7	100.6	0	0	0	112.5	D268 I269	D268-L272 PolarHBondContact O-N 3.22Å; I269-L272 PolarHBondContact O-N 2.94Å
273	Y	40.1	Very low	35.4	Very low	131 Å²	131	127.6 Å²	127.6	51%	0.514	67%	0.674	S	S	.	*	H	α-helix	trans	-69.8	-31	173.4	-96.8	-89.7	0	0	0	113	I269 L275 R276	I269-Y273 HydrophobicContact CG2-CD2 3.89Å; I269-Y273 HydrophobicContact CG2-CE2 4.16Å; I269-Y273 PolarHBondContact O-N 3.43Å; Y273-L275 VanDerWaalsContact C-N 3.34Å; Y273-L275 PolarHBondContact O-N 3.37Å; Y273-R276 WeakPolarHBondContact O-CB 3.37Å; Y273-R276 PolarHBondContact O-N 3.36Å; Y273-R276 PolarHBondContact OH-NH1 3.11Å
274	A	32.1	Very low	35.2	Very low	73 Å²	73	129.4 Å²	129.4	60%	0.603	67%	0.669	S	S	*	*	H	α-helix	trans	-67.3	-31.2	176.7	0	0	0	0	0	113.2	S270 R271 R276	S270-A274 WeakPolarHBondContact O-CB 3.24Å; S270-A274 PolarHBondContact O-N 2.89Å; R271-A274 PolarHBondContact O-N 3.48Å; A274-R276 PolarHBondContact O-N 3.19Å
275	L	39.3	Very low	34.8	Very low	141 Å²	141	127.3 Å²	127.3	74%	0.738	66%	0.659	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.3	-13.7	171.7	-80.5	166.1	0	0	0	113.2	R271 Y273	R271-L275 PolarHBondContact O-N 3.4Å; Y273-L275 VanDerWaalsContact C-N 3.34Å; Y273-L275 PolarHBondContact O-N 3.37Å
276	R	43.5	Very low	34.8	Very low	170 Å²	170	132.4 Å²	132.4	64%	0.642	67%	0.67	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.6	-20.8	-173.7	-165.2	170.2	179.9	178.7	0.1	114.4	Y273 A274	Y273-R276 WeakPolarHBondContact O-CB 3.37Å; Y273-R276 PolarHBondContact O-N 3.36Å; Y273-R276 PolarHBondContact OH-NH1 3.11Å; A274-R276 PolarHBondContact O-N 3.19Å
277	H	30.7	Very low	34.8	Very low	163 Å²	163	130.4 Å²	130.4	76%	0.755	67%	0.673	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.7	-11	-174.4	-99.2	-69.9	0	0	0	115.8
278	N	27.2	Very low	34.3	Very low	164 Å²	164	133 Å²	133	88%	0.877	68%	0.681	S	S	*	*	T	Hydrogen-bonded Turn	trans	-103.3	4	-179.2	-85.5	-3.4	0	0	0	114.9
279	M	32.5	Very low	34	Very low	132 Å²	132	135.5 Å²	135.5	65%	0.65	70%	0.699	S	S	*	*			trans	-122.9	45.2	-176	-156.4	128	73.2	0	0	112.7	Q281 L282	M279-Q281 PolarHBondContact O-N 2.85Å; M279-L282 HydrophobicContact CG-CD1 3.82Å; M279-L282 HydrophobicContact SD-CD1 3.52Å; M279-L282 VanDerWaalsContact SD-CD1 3.52Å
280	S	30.9	Very low	33.1	Very low	115 Å²	115	136.1 Å²	136.1	80%	0.804	71%	0.711	S	S	*	*	S	Bend	trans	-84.3	14.4	172.7	60.6	0	0	0	0	113.9
281	Q	33.3	Very low	33	Very low	179 Å²	179	137.5 Å²	137.5	84%	0.836	72%	0.718	S	S	*	*			trans	-144.6	93.5	168.6	-86.1	-173.6	-15.1	0	0	109.4	M279	M279-Q281 PolarHBondContact O-N 2.85Å
282	L	33.8	Very low	32.7	Very low	126 Å²	126	135 Å²	135	66%	0.66	72%	0.724	S	S	*	*			trans	-145.6	104.6	153.9	-106.1	137	0	0	0	108.9	M279 F284	M279-L282 HydrophobicContact CG-CD1 3.82Å; M279-L282 HydrophobicContact SD-CD1 3.52Å; M279-L282 VanDerWaalsContact SD-CD1 3.52Å; L282-F284 PolarHBondContact O-N 3.2Å
283	D	24.1	Very low	32.1	Very low	136 Å²	136	134.8 Å²	134.8	73%	0.727	73%	0.728	S	S	*	*			trans	-60.6	113.8	164.2	-170.5	-6.4	0	0	0	107.9	S285	D283-S285 PolarHBondContact O-N 3.25Å; D283-S285 WeakPolarHBondContact OD1-CB 3.4Å; D283-S285 PolarHBondContact OD1-OG 2.98Å
284	F	35.7	Very low	31.3	Very low	139 Å²	139	134.8 Å²	134.8	61%	0.61	74%	0.741	S	S	*	*	S	Bend	trans	-82.1	48.4	-176.4	-128.6	-91.6	0	0	0	111	Q249 L282	Q249-F284 PolarHBondContact OE1-O 3.28Å; L282-F284 PolarHBondContact O-N 3.2Å
285	S	30.1	Very low	30.9	Very low	71 Å²	71	136.6 Å²	136.6	50%	0.497	75%	0.75	S	S	.	*			trans	-128.5	47.8	-174.5	-53.1	0	0	0	0	111.6	D283	D283-S285 PolarHBondContact O-N 3.25Å; D283-S285 WeakPolarHBondContact OD1-CB 3.4Å; D283-S285 PolarHBondContact OD1-OG 2.98Å
286	R	30.7	Very low	30.4	Very low	223 Å²	223	136.9 Å²	136.9	84%	0.842	75%	0.752	S	S	*	*			trans	-176.3	120.2	157	-110.5	166.9	171.5	91.9	-1	110.4	D288	R286-D288 VanDerWaalsContact C-N 3.3Å; R286-D288 PolarHBondContact O-N 2.88Å
287	A	36.9	Very low	29.7	Very low	100 Å²	100	137.4 Å²	137.4	83%	0.826	76%	0.762	S	S	*	*			trans	-68.4	95.9	154.6	0	0	0	0	0	107.3
288	D	27.5	Very low	29.7	Very low	140 Å²	140	133 Å²	133	75%	0.749	76%	0.76	S	S	*	*			trans	-166.5	93.1	155.1	-97.7	-28.4	0	0	0	107.7	R286 S290	R286-D288 VanDerWaalsContact C-N 3.3Å; R286-D288 PolarHBondContact O-N 2.88Å; D288-S290 PolarHBondContact O-N 3.45Å
289	V	32.2	Very low	29.7	Very low	147 Å²	147	133.2 Å²	133.2	89%	0.891	76%	0.761	S	S	*	*			trans	-94.4	89.5	170.3	-176	0	0	0	0	107.4
290	S	25.4	Very low	29.6	Very low	100 Å²	100	135.3 Å²	135.3	70%	0.699	77%	0.769	S	S	*	*	P	Polyproline II helix	trans	-90.1	139.2	154.1	-71.4	0	0	0	0	108.7	D288 V292	D288-S290 PolarHBondContact O-N 3.45Å; S290-V292 PolarHBondContact O-N 3.37Å
291	P	30.8	Very low	29.6	Very low	116 Å²	116	138.6 Å²	138.6	75%	0.753	77%	0.771	S	S	*	*	P	Polyproline II helix	trans	-77.7	126	-172	29.8	-31.1	0	0	0	110.9
292	V	28.1	Very low	29.3	Very low	143 Å²	143	136 Å²	136	87%	0.867	77%	0.768	S	S	*	*	P	Polyproline II helix	trans	-82.6	116.7	168.9	170.9	0	0	0	0	108.8	S290	S290-V292 PolarHBondContact O-N 3.37Å
293	V	28.7	Very low	29	Very low	122 Å²	122	135.9 Å²	135.9	74%	0.739	77%	0.773	S	S	*	*	P	Polyproline II helix	trans	-90.5	130.7	170.8	171.4	0	0	0	0	109.1
294	T	24.2	Very low	29.1	Very low	131 Å²	131	133.3 Å²	133.3	80%	0.804	77%	0.765	S	S	*	*			trans	-161.7	130.8	137.9	31.5	0	0	0	0	106.8
295	S	24.3	Very low	28.9	Very low	111 Å²	111	133 Å²	133	78%	0.776	77%	0.774	S	S	*	*			cis	-163.7	158.6	44.9	48.4	0	0	0	0	113.1
296	N	26.8	Very low	28.5	Very low	146 Å²	146	137 Å²	137	78%	0.781	79%	0.785	S	S	*	*			trans	-23.1	144.5	167.3	-72.1	-9.7	0	0	0	116.3
297	Q	29.6	Very low	28.8	Very low	182 Å²	182	134.1 Å²	134.1	85%	0.85	78%	0.779	S	S	*	*			cis	-168.7	141.4	16.7	-125.4	171.5	-0.7	0	0	107.9
298	G	30	Very low	28.5	Very low	70 Å²	70	137.3 Å²	137.3	72%	0.722	78%	0.776	S	S	*	*	S	Bend	trans	110.3	104.3	156.4	0	0	0	0	0	117.1
299	D	27.6	Very low	29.2	Very low	168 Å²	168	134.3 Å²	134.3	90%	0.898	77%	0.765	S	S	*	*			trans	74.6	103.2	161.7	-59.1	-24.3	0	0	0	119.6	H301	D299-H301 PolarHBondContact O-N 2.95Å
300	H	31.4	Very low	30	Very low	177 Å²	177	133.6 Å²	133.6	82%	0.819	75%	0.751	S	S	*	*			trans	-70.6	106	-175.7	-75.9	-80.3	0	0	0	113.7
301	H	29.7	Very low	31.2	Very low	183 Å²	183	133.4 Å²	133.4	85%	0.847	75%	0.748	S	S	*	*			trans	-124.9	98.6	141.4	-94.9	-68.1	0	0	0	108	D299 T303	D299-H301 PolarHBondContact O-N 2.95Å; H301-T303 PolarHBondContact O-N 3.1Å; H301-T303 VanDerWaalsContact O-N 3.09Å
302	T	27.2	Very low	32.5	Very low	126 Å²	126	132.9 Å²	132.9	77%	0.773	74%	0.739	S	S	*	*			trans	-70.3	98.6	170.4	40.5	0	0	0	0	108.9	S304	T302-S304 VanDerWaalsContact C-N 3.29Å; T302-S304 PolarHBondContact O-N 3.41Å; T302-S304 VanDerWaalsContact O-N 3.12Å
303	T	29.1	Very low	34.1	Very low	123 Å²	123	126.8 Å²	126.8	76%	0.755	70%	0.701	S	S	*	*			trans	-78.6	87.4	162.3	-35.5	0	0	0	0	107.3	H301 V305	H301-T303 PolarHBondContact O-N 3.1Å; H301-T303 VanDerWaalsContact O-N 3.09Å; T303-V305 PolarHBondContact O-N 3Å; T303-V305 VanDerWaalsContact O-N 3.08Å
304	S	25	Very low	35.7	Very low	82 Å²	82	125.9 Å²	125.9	57%	0.573	69%	0.689	S	S	*	*			trans	-59.9	106.7	159.9	51.7	0	0	0	0	107.1	T302 H306	T302-S304 VanDerWaalsContact C-N 3.29Å; T302-S304 PolarHBondContact O-N 3.41Å; T302-S304 VanDerWaalsContact O-N 3.12Å; S304-H306 PolarHBondContact O-N 3.13Å
305	V	30.8	Very low	38	Very low	131 Å²	131	126 Å²	126	79%	0.794	68%	0.681	S	S	*	*			trans	-71.2	91.9	167.7	-176.5	0	0	0	0	106.1	T303 F307	T303-V305 PolarHBondContact O-N 3Å; T303-V305 VanDerWaalsContact O-N 3.08Å; V305-F307 PolarHBondContact O-N 3.08Å
306	H	23.6	Very low	40.4	Very low	157 Å²	157	121.7 Å²	121.7	73%	0.727	65%	0.648	S	S	*	*			trans	-63	111.5	163	-89.6	-78.3	0	0	0	106.8	S304 E308	S304-H306 PolarHBondContact O-N 3.13Å; H306-E308 PolarHBondContact O-N 2.93Å
307	F	35.8	Very low	43.1	Very low	161 Å²	161	116 Å²	116	71%	0.706	62%	0.619	S	S	*	*			trans	-74.3	88.3	162.5	-163.1	-90.8	0	0	0	106	V305 P309	V305-F307 PolarHBondContact O-N 3.08Å; F307-P309 WeakPolarHBondContact O-CD 3.41Å
308	E	31	Very low	45.8	Very low	167 Å²	167	114.2 Å²	114.2	78%	0.78	61%	0.605	S	S	*	*	P	Polyproline II helix	trans	-65.3	120.8	161.6	-98.3	176.6	129.8	0	0	106.5	H306 H310	H306-E308 PolarHBondContact O-N 2.93Å; E308-H310 PolarHBondContact O-N 2.93Å
309	P	42.1	Very low	48.6	Very low	77 Å²	77	113 Å²	113	50%	0.5	58%	0.584	S	S	.	*	P	Polyproline II helix	trans	-56.1	126.9	174.5	-16.2	27.4	0	0	0	108	F307	F307-P309 WeakPolarHBondContact O-CD 3.41Å
310	H	49	Very low	51.7	Low	132 Å²	132	108.8 Å²	108.8	61%	0.611	56%	0.558	S	S	*	*	P	Polyproline II helix	trans	-62	142.4	167.5	-103.5	-30	0	0	0	107.7	E308 D312 D313	E308-H310 PolarHBondContact O-N 2.93Å; H310-D312 PolarHBondContact O-N 3.14Å; H310-D313 PolarHBondContact N-OD2 2.99Å; H310-D313 WeakPolarHBondContact O-CB 3.37Å; H310-D313 PolarHBondContact O-N 3.26Å
311	P	50.6	Low	54.5	Low	97 Å²	97	106.8 Å²	106.8	63%	0.63	54%	0.544	S	S	*	.	H	α-helix	trans	-55.1	-26.6	-178.4	18.7	-29.7	0	0	0	112.9
312	D	59.1	Low	57.5	Low	105 Å²	105	104 Å²	104	56%	0.561	53%	0.53	S	S	*	.	H	α-helix	trans	-69.2	-31.5	175.8	-56.7	-32.3	0	0	0	113	H310 E315 M316	H310-D312 PolarHBondContact O-N 3.14Å; D312-E315 PolarHBondContact O-N 2.89Å; D312-M316 VanDerWaalsContact O-CG 3.29Å; D312-M316 WeakPolarHBondContact O-CG 3.06Å; D312-M316 PolarHBondContact O-N 2.86Å
313	D	60.6	Low	60.5	Low	15 Å²	15	99 Å²	99	8%	0.08	50%	0.499	C	S	.	.	H	α-helix	trans	-68.7	-36.7	179.2	-66.3	-38.2	0	0	0	112	P253 Y258 H310 E315	P253-D313 HydrophobicContact CG-CB 4.29Å; Y258-D313 WeakPolarHBondContact CE1-OD1 3.32Å; Y258-D313 PolarHBondContact OH-OD1 3.32Å; Y258-D313 PolarHBondContact OH-OD2 3.27Å; H310-D313 PolarHBondContact N-OD2 2.99Å; H310-D313 WeakPolarHBondContact O-CB 3.37Å; H310-D313 PolarHBondContact O-N 3.26Å; D313-E315 VanDerWaalsContact C-N 3.31Å
314	E	62.2	Low	63.2	Low	102 Å²	102	100.8 Å²	100.8	48%	0.477	50%	0.497	S	S	.	.	H	α-helix	trans	-68.3	-31.4	175.1	-94.1	-163.3	180	0	0	112.1	R318	E314-R318 VanDerWaalsContact O-CD 3.29Å; E314-R318 WeakPolarHBondContact O-CD 3.48Å; E314-R318 WeakPolarHBondContact O-CG 3Å; E314-R318 PolarHBondContact O-NE 3.45Å; E314-R318 IonicContact OE2-CZ 3.72Å; E314-R318 IonicContact OE2-NH2 3.07Å; E314-R318 PolarHBondContact OE2-NH2 2.81Å
315	E	73	Confident	66	Low	135 Å²	135	99.9 Å²	99.9	63%	0.631	49%	0.486	S	S	*	.	H	α-helix	trans	-73.6	-37.8	179.9	-165	170.4	-179.9	0	0	111.8	D312 D313 C317 R318	D312-E315 PolarHBondContact O-N 2.89Å; D313-E315 VanDerWaalsContact C-N 3.31Å; E315-C317 VanDerWaalsContact C-N 3.25Å; E315-C317 PolarHBondContact O-N 3.37Å; E315-R318 PolarHBondContact O-N 3.17Å
316	M	75.1	Confident	68.4	Low	19 Å²	19	97.1 Å²	97.1	9%	0.094	47%	0.472	C	S	.	.	H	α-helix	trans	-64.7	-27.3	-179.8	-66.8	169	76.2	0	0	113.7	M257 D312 F389	M257-M316 HydrophobicContact CB-CE 3.3Å; M257-M316 HydrophobicContact CG-CE 4.33Å; M257-M316 HydrophobicContact SD-CE 4.26Å; D312-M316 VanDerWaalsContact O-CG 3.29Å; D312-M316 WeakPolarHBondContact O-CG 3.06Å; D312-M316 PolarHBondContact O-N 2.86Å; M316-F389 HydrophobicContact CE-CE2 4.05Å; M316-F389 HydrophobicContact CE-CZ 4.03Å
317	C	82.1	Confident	71.3	Confident	26 Å²	26	91.3 Å²	91.3	18%	0.176	45%	0.445	C	S	.	.	T	Hydrogen-bonded Turn	trans	-104.8	13.3	-177.5	-61.8	0	0	0	0	113.5	C252 P253 E315 Y387	C252-C317 HydrophobicContact CB-CB 3.87Å; C252-C317 WeakPolarHBondContact CB-SG 3.45Å; C252-C317 VanDerWaalsContact SG-CA 3.56Å; C252-C317 WeakPolarHBondContact SG-CB 3.36Å; C252-C317 CovalentContact SG-SG 2.03Å; C252-C317 PolarHBondContact SG-SG 2.88Å; P253-C317 VanDerWaalsContact CA-SG 3.52Å; E315-C317 VanDerWaalsContact C-N 3.25Å; E315-C317 PolarHBondContact O-N 3.37Å; C317-Y387 VanDerWaalsContact C-CE1 3.47Å; C317-Y387 HydrophobicContact CB-CE2 4.47Å; C317-Y387 VanDerWaalsContact O-CE1 3.23Å; C317-Y387 WeakPolarHBondContact O-CE1 3.43Å; C317-Y387 PolarHBondContact O-OH 2.81Å
318	R	86.4	Confident	73.6	Confident	146 Å²	146	84.9 Å²	84.9	55%	0.551	42%	0.419	S	S	*	.	S	Bend	trans	-92.9	126.8	178.4	-87.5	170.4	-170.3	-142.4	7.6	111.6	E314 E315 K320	E314-R318 VanDerWaalsContact O-CD 3.29Å; E314-R318 WeakPolarHBondContact O-CD 3.48Å; E314-R318 WeakPolarHBondContact O-CG 3Å; E314-R318 PolarHBondContact O-NE 3.45Å; E314-R318 IonicContact OE2-CZ 3.72Å; E314-R318 IonicContact OE2-NH2 3.07Å; E314-R318 PolarHBondContact OE2-NH2 2.81Å; E315-R318 PolarHBondContact O-N 3.17Å; R318-K320 PolarHBondContact O-N 3.02Å
319	P	90.1	Very high	76.2	Confident	44 Å²	44	78.1 Å²	78.1	29%	0.286	39%	0.392	S	S	.	.	P	Polyproline II helix	trans	-68.3	128.9	177.5	27.6	-32.9	0	0	0	110.3	I108 Y383 L384 Y387	I108-P319 HydrophobicContact CD1-CB 3.79Å; P319-Y383 HydrophobicContact CB-CE1 4.46Å; P319-L384 HydrophobicContact CB-CD2 4.21Å; P319-Y387 HydrophobicContact CB-CE1 4.36Å
320	K	91.1	Very high	78.5	Confident	79 Å²	79	74.5 Å²	74.5	34%	0.343	37%	0.368	S	S	.	.	P	Polyproline II helix	trans	-89	126.7	173.9	-65.6	177.8	-179.9	163.4	0	109.7	G107 I108 R318 V323 Y383 D388	G107-K320 CarbonylContact C-O 3.59Å; G107-K320 WeakPolarHBondContact CA-O 3.49Å; I108-K320 PolarHBondContact N-O 2.84Å; R318-K320 PolarHBondContact O-N 3.02Å; K320-V323 HydrophobicContact CB-CG2 3.58Å; K320-V323 HydrophobicContact CD-CG2 3.79Å; K320-V323 HydrophobicContact CG-CG2 4.3Å; K320-Y383 PolarHBondContact N-OH 3.4Å; K320-D388 WeakPolarHBondContact CE-OD2 3.25Å; K320-D388 IonicContact NZ-OD1 2.75Å; K320-D388 PolarHBondContact NZ-OD1 2.82Å; K320-D388 IonicContact NZ-OD2 3.77Å; K320-D388 PolarHBondContact NZ-OD2 2.99Å
321	Y	91.8	Very high	80.6	Confident	135 Å²	135	68.2 Å²	68.2	53%	0.529	34%	0.339	S	S	.	.	S	Bend	trans	-86.2	-33.3	-179.8	-64.4	-81.2	0	0	0	112.5	G107 I108 V109	G107-Y321 CarbonylContact C-O 3.37Å; I108-Y321 PolarHBondContact N-O 3.03Å; V109-Y321 HydrophobicContact CG2-CD1 3.85Å; V109-Y321 HydrophobicContact CG2-CG 4.37Å; V109-Y321 PolarHBondContact N-O 3.44Å; V109-Y321 VanDerWaalsContact N-O 3.09Å
322	F	92.1	Very high	82.6	Confident	125 Å²	125	65.6 Å²	65.6	55%	0.548	32%	0.321	S	S	.	.			trans	-135	129.4	176.8	-63.8	-83.4	0	0	0	109.6	V109 L110 F324	V109-F322 HydrophobicContact CB-CE1 4.1Å; V109-F322 HydrophobicContact CB-CE2 4.26Å; V109-F322 HydrophobicContact CB-CZ 3.84Å; V109-F322 HydrophobicContact CG1-CE1 3.93Å; V109-F322 HydrophobicContact CG1-CE2 4.37Å; V109-F322 HydrophobicContact CG1-CZ 3.59Å; V109-F322 HydrophobicContact CG2-CE2 4.47Å; V109-F322 HydrophobicContact CG2-CZ 4.45Å; L110-F322 HydrophobicContact CB-CD1 4.22Å; F322-F324 HydrophobicContact CB-CE2 4.43Å
323	V	89.5	Confident	84.3	Confident	22 Å²	22	60.6 Å²	60.6	13%	0.133	29%	0.294	C	S	.	.			trans	-136.2	132.4	175	-178.1	0	0	0	0	107.9	T106 K320	T106-V323 WeakPolarHBondContact CA-O 3.23Å; T106-V323 PolarHBondContact O-N 3.4Å; K320-V323 HydrophobicContact CB-CG2 3.58Å; K320-V323 HydrophobicContact CD-CG2 3.79Å; K320-V323 HydrophobicContact CG-CG2 4.3Å
324	F	86.9	Confident	85.9	Confident	159 Å²	159	59.9 Å²	59.9	70%	0.697	29%	0.291	S	S	*	.			trans	-127.8	110.8	173.1	-66.2	-79.7	0	0	0	108.1	L110 F322	L110-F324 HydrophobicContact CD2-CD1 4.44Å; L110-F324 HydrophobicContact CD2-CE1 3.69Å; L110-F324 HydrophobicContact CD2-CZ 3.89Å; F322-F324 HydrophobicContact CB-CE2 4.43Å
325	N	84.3	Confident	87.5	Confident	64 Å²	64	55 Å²	55	34%	0.342	27%	0.268	S	S	.	.			trans	-138	178.3	177.1	67.1	21.7	0	0	0	109.9	N105 Q327 T328	N105-N325 PolarHBondContact OD1-ND2 3.36Å; N325-Q327 PolarHBondContact O-N 2.85Å; N325-Q327 VanDerWaalsContact OD1-CA 3.31Å; N325-Q327 WeakPolarHBondContact OD1-CA 3.07Å; N325-Q327 VanDerWaalsContact OD1-CB 3.28Å; N325-Q327 WeakPolarHBondContact OD1-CB 3.42Å; N325-Q327 PolarHBondContact OD1-N 3.49Å; N325-T328 PolarHBondContact N-OG1 3.38Å; N325-T328 VanDerWaalsContact O-CB 3.28Å; N325-T328 WeakPolarHBondContact O-CB 3.31Å; N325-T328 PolarHBondContact O-N 2.91Å; N325-T328 PolarHBondContact O-OG1 3.49Å; N325-T328 PolarHBondContact OD1-N 3.24Å; N325-T328 PolarHBondContact OD1-OG1 3.36Å
326	S	80.4	Confident	88.6	Confident	72 Å²	72	48.7 Å²	48.7	50%	0.503	24%	0.238	S	C	.	.	T	Hydrogen-bonded Turn	trans	-61.6	-30.6	177	52.5	0	0	0	0	112.7	T328 A329	S326-T328 VanDerWaalsContact C-N 3.32Å; S326-T328 PolarHBondContact O-N 3.42Å; S326-A329 WeakPolarHBondContact O-CB 3.33Å; S326-A329 PolarHBondContact O-N 2.99Å
327	Q	83.8	Confident	89.5	Confident	35 Å²	35	48.3 Å²	48.3	16%	0.164	24%	0.236	C	C	.	.	T	Hydrogen-bonded Turn	trans	-73.5	-21	-179.8	-56.1	-57.7	-37.1	0	0	113.3	Y101 N105 N325 A329 Y330 R471	Y101-Q327 PolarHBondContact OH-OE1 2.92Å; N105-Q327 HydrophobicContact CB-CB 4.14Å; N105-Q327 WeakPolarHBondContact OD1-CB 3.33Å; N325-Q327 PolarHBondContact O-N 2.85Å; N325-Q327 VanDerWaalsContact OD1-CA 3.31Å; N325-Q327 WeakPolarHBondContact OD1-CA 3.07Å; N325-Q327 VanDerWaalsContact OD1-CB 3.28Å; N325-Q327 WeakPolarHBondContact OD1-CB 3.42Å; N325-Q327 PolarHBondContact OD1-N 3.49Å; Q327-A329 PolarHBondContact O-N 3.4Å; Q327-A329 VanDerWaalsContact O-N 3.08Å; Q327-Y330 WeakPolarHBondContact O-CB 2.97Å; Q327-Y330 PolarHBondContact O-N 2.97Å; Q327-R471 VanDerWaalsContact CD-NH1 3.33Å
328	T	85.7	Confident	90.1	Very high	27 Å²	27	47.1 Å²	47.1	17%	0.166	23%	0.229	C	C	.	.	H	α-helix	trans	-54.1	-28.8	173.2	-55.2	0	0	0	0	111.8	N105 T106 N325 S326 Y330 T331	N105-T328 PolarHBondContact O-OG1 2.98Å; T106-T328 HydrophobicContact CG2-CG2 3.72Å; N325-T328 PolarHBondContact N-OG1 3.38Å; N325-T328 VanDerWaalsContact O-CB 3.28Å; N325-T328 WeakPolarHBondContact O-CB 3.31Å; N325-T328 PolarHBondContact O-N 2.91Å; N325-T328 PolarHBondContact O-OG1 3.49Å; N325-T328 PolarHBondContact OD1-N 3.24Å; N325-T328 PolarHBondContact OD1-OG1 3.36Å; S326-T328 VanDerWaalsContact C-N 3.32Å; S326-T328 PolarHBondContact O-N 3.42Å; T328-Y330 PolarHBondContact O-N 2.93Å; T328-T331 WeakPolarHBondContact O-CB 3.38Å; T328-T331 PolarHBondContact O-N 3.44Å; T328-T331 VanDerWaalsContact O-N 3.13Å
329	A	85.6	Confident	90.6	Very high	25 Å²	25	40.2 Å²	40.2	21%	0.207	20%	0.202	C	C	.	.	H	α-helix	trans	-59.5	-29.1	176	0	0	0	0	0	113.4	S326 Q327 P333 L528	S326-A329 WeakPolarHBondContact O-CB 3.33Å; S326-A329 PolarHBondContact O-N 2.99Å; Q327-A329 PolarHBondContact O-N 3.4Å; Q327-A329 VanDerWaalsContact O-N 3.08Å; A329-P333 WeakPolarHBondContact O-CD 3.28Å; A329-L528 HydrophobicContact CB-CB 4.04Å; A329-L528 HydrophobicContact CB-CD1 4.08Å
330	Y	90.1	Very high	90.8	Very high	0 Å²	0	38.6 Å²	38.6	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-83.3	-20.1	179.3	-70.2	-96	0	0	0	112.7	Q327 T328 P333 I334 R471 I529 D532	Q327-Y330 WeakPolarHBondContact O-CB 2.97Å; Q327-Y330 PolarHBondContact O-N 2.97Å; T328-Y330 PolarHBondContact O-N 2.93Å; Y330-P333 WeakPolarHBondContact O-CD 3.47Å; Y330-I334 WeakPolarHBondContact O-CB 3.18Å; Y330-I334 VanDerWaalsContact O-CD1 3.31Å; Y330-I334 WeakPolarHBondContact O-CD1 3.48Å; Y330-I334 WeakPolarHBondContact O-CG1 3.34Å; Y330-I334 PolarHBondContact O-N 2.9Å; Y330-R471 HydrophobicContact CD1-CG 3.82Å; Y330-R471 HydrophobicContact CE1-CG 4.42Å; Y330-R471 HydrophobicContact CG-CG 4.08Å; Y330-I529 HydrophobicContact CD1-CG1 4.28Å; Y330-I529 HydrophobicContact CE1-CB 4.48Å; Y330-I529 HydrophobicContact CE1-CD1 4.46Å; Y330-I529 HydrophobicContact CE1-CG1 3.86Å; Y330-I529 HydrophobicContact CE1-CG2 4.1Å; Y330-D532 HydrophobicContact CE2-CB 4.19Å; Y330-D532 WeakPolarHBondContact OH-CB 3.46Å; Y330-D532 PolarHBondContact OH-OD2 3.43Å
331	T	92.4	Very high	90.9	Very high	1 Å²	1	34.9 Å²	34.9	1%	0.006	18%	0.176	C	C	.	.	H	α-helix	trans	-61	-53.5	-175.1	-68	0	0	0	0	112.4	A102 T106 L114 T328 I334 L335	A102-T331 HydrophobicContact CB-CG2 3.98Å; A102-T331 PolarHBondContact O-OG1 3.18Å; T106-T331 HydrophobicContact CG2-CG2 3.7Å; T106-T331 WeakPolarHBondContact CG2-OG1 3.4Å; L114-T331 HydrophobicContact CD1-CG2 4.14Å; T328-T331 WeakPolarHBondContact O-CB 3.38Å; T328-T331 PolarHBondContact O-N 3.44Å; T328-T331 VanDerWaalsContact O-N 3.13Å; T331-I334 WeakPolarHBondContact O-CB 3.45Å; T331-I334 PolarHBondContact O-N 3.28Å; T331-I334 VanDerWaalsContact O-N 3.14Å; T331-L335 HydrophobicContact CG2-CD1 4.2Å; T331-L335 HydrophobicContact CG2-CG 4.33Å; T331-L335 WeakPolarHBondContact O-CG 3.4Å; T331-L335 PolarHBondContact O-N 3.37Å
332	V	92.2	Very high	91	Very high	41 Å²	41	28.5 Å²	28.5	25%	0.248	15%	0.151	C	C	.	.	H	α-helix	trans	-63.8	-42.8	-176.3	-165.7	0	0	0	0	111.8	L114 L335 A336 F521	L114-V332 HydrophobicContact CD1-CG2 4.22Å; L114-V332 HydrophobicContact CD2-CG2 4.2Å; V332-L335 PolarHBondContact O-N 3.43Å; V332-A336 PolarHBondContact O-N 2.97Å; V332-F521 HydrophobicContact CB-CE2 3.59Å; V332-F521 HydrophobicContact CB-CZ 3.71Å; V332-F521 HydrophobicContact CG1-CD2 4.26Å; V332-F521 HydrophobicContact CG1-CE1 4.34Å; V332-F521 HydrophobicContact CG1-CE2 3.23Å; V332-F521 HydrophobicContact CG1-CZ 3.3Å
333	P	94.8	Very high	90.9	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-56.2	-45.2	168.6	-30.9	38.7	0	0	0	114.6	A329 Y330 L335 A336 F337 G475 G478 A479 F521 I529	A329-P333 WeakPolarHBondContact O-CD 3.28Å; Y330-P333 WeakPolarHBondContact O-CD 3.47Å; P333-L335 VanDerWaalsContact C-N 3.28Å; P333-L335 PolarHBondContact O-N 2.89Å; P333-A336 PolarHBondContact O-N 3.19Å; P333-F337 WeakPolarHBondContact O-CB 3.42Å; P333-F337 PolarHBondContact O-N 2.83Å; P333-G475 WeakPolarHBondContact CB-O 3.43Å; P333-G478 VanDerWaalsContact O-CA 3.26Å; P333-G478 WeakPolarHBondContact O-CA 3.49Å; P333-A479 HydrophobicContact CB-CB 4.13Å; P333-A479 HydrophobicContact CG-CB 4.02Å; P333-F521 HydrophobicContact CG-CZ 4.33Å; P333-I529 HydrophobicContact CG-CD1 4.31Å
334	I	95.1	Very high	90.9	Very high	1 Å²	1	23.7 Å²	23.7	1%	0.005	13%	0.13	C	C	.	.	H	α-helix	trans	-58	-43.4	176.3	-70.3	161.3	0	0	0	110.4	L99 Y101 A102 Y330 T331 F337 A338 F474	L99-I334 HydrophobicContact CD2-CG2 4.43Å; Y101-I334 HydrophobicContact CD1-CD1 4.23Å; Y101-I334 HydrophobicContact CE1-CD1 4.43Å; A102-I334 HydrophobicContact CB-CG2 4.44Å; Y330-I334 WeakPolarHBondContact O-CB 3.18Å; Y330-I334 VanDerWaalsContact O-CD1 3.31Å; Y330-I334 WeakPolarHBondContact O-CD1 3.48Å; Y330-I334 WeakPolarHBondContact O-CG1 3.34Å; Y330-I334 PolarHBondContact O-N 2.9Å; T331-I334 WeakPolarHBondContact O-CB 3.45Å; T331-I334 PolarHBondContact O-N 3.28Å; T331-I334 VanDerWaalsContact O-N 3.14Å; I334-F337 PolarHBondContact O-N 2.95Å; I334-A338 WeakPolarHBondContact O-CB 3.18Å; I334-A338 PolarHBondContact O-N 2.8Å; I334-F474 HydrophobicContact CB-CB 4.47Å; I334-F474 HydrophobicContact CG1-CB 3.69Å
335	L	95.5	Very high	91.2	Very high	0 Å²	0	16.1 Å²	16.1	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-66.8	-40.9	177.4	-62.8	-174.3	0	0	0	112.4	L99 F111 L114 L115 V118 T331 V332 P333 F337 A338 F339	L99-L335 HydrophobicContact CD2-CD2 3.52Å; F111-L335 HydrophobicContact CE2-CD2 3.84Å; F111-L335 HydrophobicContact CZ-CD2 4.18Å; L114-L335 HydrophobicContact CB-CD1 3.63Å; L115-L335 HydrophobicContact CD1-CD1 4.41Å; L115-L335 HydrophobicContact CD1-CD2 3.45Å; L115-L335 VanDerWaalsContact CD1-CD2 3.45Å; L115-L335 HydrophobicContact CD1-CG 4.42Å; V118-L335 HydrophobicContact CB-CB 4.46Å; V118-L335 HydrophobicContact CG1-CB 4.44Å; V118-L335 HydrophobicContact CG2-CB 4.15Å; T331-L335 HydrophobicContact CG2-CD1 4.2Å; T331-L335 HydrophobicContact CG2-CG 4.33Å; T331-L335 WeakPolarHBondContact O-CG 3.4Å; T331-L335 PolarHBondContact O-N 3.37Å; V332-L335 PolarHBondContact O-N 3.43Å; P333-L335 VanDerWaalsContact C-N 3.28Å; P333-L335 PolarHBondContact O-N 2.89Å; L335-F337 VanDerWaalsContact C-N 3.33Å; L335-A338 PolarHBondContact O-N 3.45Å; L335-F339 PolarHBondContact O-N 2.69Å; L335-F339 VanDerWaalsContact O-N 3.11Å
336	A	95	Very high	91.5	Very high	1 Å²	1	13.1 Å²	13.1	1%	0.008	8%	0.08	C	C	.	.	H	α-helix	trans	-61.3	-44.2	175.1	0	0	0	0	0	110.9	V332 P333 A338 F339 V340 A482 I486 F521	V332-A336 PolarHBondContact O-N 2.97Å; P333-A336 PolarHBondContact O-N 3.19Å; A336-A338 VanDerWaalsContact C-N 3.34Å; A336-A338 PolarHBondContact O-N 3.09Å; A336-F339 PolarHBondContact O-N 3.21Å; A336-V340 PolarHBondContact O-N 3.49Å; A336-A482 HydrophobicContact CB-CB 4.26Å; A336-I486 HydrophobicContact CB-CD1 4.28Å; A336-I486 WeakPolarHBondContact O-CD1 3.25Å; A336-F521 HydrophobicContact CB-CE1 4.46Å
337	F	95	Very high	91.8	Very high	12 Å²	12	12.2 Å²	12.2	5%	0.053	7%	0.073	C	C	.	.	H	α-helix	trans	-61.1	-40.1	172.8	176.5	-94	0	0	0	112.1	Q164 A168 P333 I334 L335 F339 V340 F474 I477	Q164-F337 VanDerWaalsContact NE2-CE2 3.29Å; A168-F337 HydrophobicContact CB-CE2 4.45Å; A168-F337 HydrophobicContact CB-CZ 4.29Å; P333-F337 WeakPolarHBondContact O-CB 3.42Å; P333-F337 PolarHBondContact O-N 2.83Å; I334-F337 PolarHBondContact O-N 2.95Å; L335-F337 VanDerWaalsContact C-N 3.33Å; F337-F339 VanDerWaalsContact C-N 3.3Å; F337-F339 PolarHBondContact O-N 3.34Å; F337-V340 WeakPolarHBondContact O-CG1 3.47Å; F337-F474 AromaticContact CD1-CD1 3.57Å; F337-F474 HydrophobicContact CD1-CD1 3.57Å; F337-F474 AromaticContact CD1-CE1 3.96Å; F337-F474 HydrophobicContact CD1-CE1 3.96Å; F337-F474 HydrophobicContact CD1-CG 4.21Å; F337-F474 AromaticContact CE1-CD1 3.37Å; F337-F474 HydrophobicContact CE1-CD1 3.37Å; F337-F474 AromaticContact CE1-CE1 3.35Å; F337-F474 HydrophobicContact CE1-CE1 3.35Å; F337-F474 HydrophobicContact CE1-CG 4.39Å; F337-F474 HydrophobicContact CE1-CZ 4.36Å; F337-F474 HydrophobicContact CG-CD1 4.26Å; F337-F474 AromaticContact CZ-CD1 3.9Å; F337-F474 HydrophobicContact CZ-CD1 3.9Å; F337-F474 AromaticContact CZ-CE1 3.91Å; F337-F474 HydrophobicContact CZ-CE1 3.91Å; F337-I477 HydrophobicContact CD2-CB 4.11Å; F337-I477 HydrophobicContact CD2-CG2 3.72Å; F337-I477 HydrophobicContact CE2-CB 4.39Å; F337-I477 HydrophobicContact CE2-CG2 3.91Å
338	A	95.1	Very high	92.1	Very high	1 Å²	1	11.1 Å²	11.1	1%	0.008	7%	0.068	C	C	.	.	H	α-helix	trans	-69.4	-23.2	-179.6	0	0	0	0	0	114.2	I91 L99 I334 L335 A336 Y375	I91-A338 WeakPolarHBondContact CG2-O 3.31Å; L99-A338 HydrophobicContact CD2-CB 4.27Å; I334-A338 WeakPolarHBondContact O-CB 3.18Å; I334-A338 PolarHBondContact O-N 2.8Å; L335-A338 PolarHBondContact O-N 3.45Å; A336-A338 VanDerWaalsContact C-N 3.34Å; A336-A338 PolarHBondContact O-N 3.09Å; A338-Y375 HydrophobicContact CB-CE2 3.95Å; A338-Y375 WeakPolarHBondContact O-CE2 3.12Å; A338-Y375 PolarHBondContact O-OH 3.27Å; A338-Y375 VanDerWaalsContact O-OH 3.1Å
339	F	95.8	Very high	92.3	Very high	0 Å²	0	11.4 Å²	11.4	0%	0	7%	0.066	C	C	.	.	T	Hydrogen-bonded Turn	trans	-109	7.1	-178.4	-80.2	-69	0	0	0	114.6	I91 L115 V118 A119 S122 L335 A336 F337 C341 I368 L372 Y375	I91-F339 HydrophobicContact CG2-CD1 4.13Å; L115-F339 HydrophobicContact CD1-CE2 3.51Å; L115-F339 HydrophobicContact CD1-CZ 4.16Å; L115-F339 HydrophobicContact CG-CE2 3.87Å; L115-F339 HydrophobicContact CG-CZ 4.22Å; V118-F339 HydrophobicContact CB-CD2 4.3Å; V118-F339 HydrophobicContact CG1-CB 4Å; V118-F339 HydrophobicContact CG1-CD2 3.76Å; V118-F339 HydrophobicContact CG1-CG 4.26Å; A119-F339 HydrophobicContact CB-CD1 4.47Å; A119-F339 HydrophobicContact CB-CE1 3.95Å; A119-F339 HydrophobicContact CB-CE2 4.19Å; A119-F339 HydrophobicContact CB-CZ 3.79Å; S122-F339 PolarHBondContact OG-O 3.2Å; L335-F339 PolarHBondContact O-N 2.69Å; L335-F339 VanDerWaalsContact O-N 3.11Å; A336-F339 PolarHBondContact O-N 3.21Å; F337-F339 VanDerWaalsContact C-N 3.3Å; F337-F339 PolarHBondContact O-N 3.34Å; F339-C341 PolarHBondContact O-N 3.37Å; F339-I368 HydrophobicContact CD1-CG2 4.37Å; F339-I368 HydrophobicContact CE1-CG2 4.15Å; F339-L372 HydrophobicContact CZ-CB 4.45Å; F339-L372 HydrophobicContact CZ-CD1 4.07Å; F339-Y375 HydrophobicContact CD1-CE2 4.41Å; F339-Y375 HydrophobicContact CE1-CD2 4.03Å; F339-Y375 HydrophobicContact CE1-CE2 4.1Å; F339-Y375 HydrophobicContact CE2-CD2 4.04Å; F339-Y375 HydrophobicContact CE2-CE2 4.4Å; F339-Y375 AromaticContact CZ-CD2 3.65Å; F339-Y375 HydrophobicContact CZ-CD2 3.65Å; F339-Y375 HydrophobicContact CZ-CE2 4.1Å
340	V	94.8	Very high	92.4	Very high	11 Å²	11	12.3 Å²	12.3	7%	0.067	7%	0.071	C	C	.	.			trans	-78.1	106.7	176.5	67.9	0	0	0	0	110.8	Q164 A336 F337 A482 L485 I486	Q164-V340 HydrophobicContact CG-CG1 4Å; Q164-V340 HydrophobicContact CG-CG2 4.16Å; A336-V340 PolarHBondContact O-N 3.49Å; F337-V340 WeakPolarHBondContact O-CG1 3.47Å; V340-A482 HydrophobicContact CB-CB 3.97Å; V340-A482 HydrophobicContact CG1-CB 4.2Å; V340-A482 HydrophobicContact CG2-CB 4.23Å; V340-L485 HydrophobicContact CG2-CB 4.08Å; V340-L485 HydrophobicContact CG2-CD1 4.12Å; V340-I486 HydrophobicContact CB-CD1 4.02Å; V340-I486 HydrophobicContact CB-CG1 4.32Å; V340-I486 HydrophobicContact CG2-CD1 4.47Å; V340-I486 HydrophobicContact CG2-CG1 4.28Å
341	C	94	Very high	92.2	Very high	1 Å²	1	17.3 Å²	17.3	1%	0.007	9%	0.094	C	C	.	.			trans	-121.8	-3.1	172.8	62.4	0	0	0	0	113.5	L87 I91 F339 E344 V345	L87-C341 HydrophobicContact CD1-CB 3.76Å; I91-C341 HydrophobicContact CD1-CB 4.37Å; I91-C341 HydrophobicContact CG1-CB 3.55Å; F339-C341 PolarHBondContact O-N 3.37Å; C341-E344 PolarHBondContact O-N 3.31Å; C341-V345 PolarHBondContact O-N 3.03Å
342	H	93.9	Very high	92	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-52	-39	-172.4	-61.3	77.8	0	0	0	115.3	S122 S125 L129 Y141 E344 V345 L485	S122-H342 PolarHBondContact OG-CE1 3.35Å; S125-H342 WeakPolarHBondContact CB-NE2 3.41Å; S125-H342 PolarHBondContact OG-CD2 3.39Å; S125-H342 PolarHBondContact OG-NE2 3.15Å; L129-H342 HydrophobicContact CD2-CB 4.34Å; Y141-H342 HydrophobicContact CE2-CB 4.29Å; H342-E344 PolarHBondContact O-N 3.2Å; H342-V345 PolarHBondContact O-N 3.33Å; H342-L485 HydrophobicContact CB-CB 4.33Å; H342-L485 PolarHBondContact CD2-O 2.97Å
343	P	90	Very high	91.8	Very high	13 Å²	13	20.5 Å²	20.5	8%	0.084	11%	0.105	C	C	.	.	H	α-helix	trans	-59.7	-32.8	175.1	-25.9	36.9	0	0	0	113.6	I161 P347 L485	I161-P343 HydrophobicContact CG1-CB 4.34Å; I161-P343 HydrophobicContact CG1-CG 4.33Å; I161-P343 HydrophobicContact CG2-CB 4.31Å; P343-P347 VanDerWaalsContact O-CD 3.22Å; P343-P347 WeakPolarHBondContact O-CD 3.14Å; P343-L485 HydrophobicContact CG-CD1 3.7Å; P343-L485 HydrophobicContact CG-CD2 4.45Å
344	E	89.1	Confident	91.5	Very high	34 Å²	34	26 Å²	26	16%	0.159	13%	0.134	C	C	.	.	H	α-helix	trans	-92.5	-17.9	-174	-57.7	-53.9	134.7	0	0	113	A90 C341 H342 L346 P347 I348	A90-E344 HydrophobicContact CB-CB 4.11Å; A90-E344 HydrophobicContact CB-CG 3.9Å; C341-E344 PolarHBondContact O-N 3.31Å; H342-E344 PolarHBondContact O-N 3.2Å; E344-L346 PolarHBondContact O-N 3.44Å; E344-P347 WeakPolarHBondContact O-CD 3.33Å; E344-I348 HydrophobicContact CB-CD1 4.05Å; E344-I348 WeakPolarHBondContact O-CB 3.19Å; E344-I348 WeakPolarHBondContact O-CD1 3.43Å; E344-I348 WeakPolarHBondContact O-CG1 3.28Å; E344-I348 PolarHBondContact O-N 3.35Å
345	V	92.6	Very high	91.1	Very high	0 Å²	0	29.9 Å²	29.9	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-58.2	-48.1	-178.1	169	0	0	0	0	112	L87 V126 L129 L130 C341 H342 Y349 M360	L87-V345 HydrophobicContact CD1-CG2 4.05Å; V126-V345 HydrophobicContact CG1-CG1 4.12Å; V126-V345 HydrophobicContact CG1-CG2 4.35Å; V126-V345 HydrophobicContact CG2-CG2 4.11Å; L129-V345 HydrophobicContact CD2-CB 4.32Å; L129-V345 HydrophobicContact CD2-CG1 4.36Å; L130-V345 HydrophobicContact CD2-CG1 3.93Å; L130-V345 HydrophobicContact CG-CG1 4.36Å; C341-V345 PolarHBondContact O-N 3.03Å; H342-V345 PolarHBondContact O-N 3.33Å; V345-Y349 VanDerWaalsContact O-CB 3.25Å; V345-Y349 WeakPolarHBondContact O-CB 3.31Å; V345-Y349 PolarHBondContact O-N 3.34Å; V345-M360 HydrophobicContact CB-CE 4.43Å; V345-M360 HydrophobicContact CG1-CE 3.94Å; V345-M360 WeakPolarHBondContact O-CE 3.31Å
346	L	90.5	Very high	90.9	Very high	1 Å²	1	32.2 Å²	32.2	1%	0.005	17%	0.165	C	C	.	.	H	α-helix	trans	-72.1	-43.3	-176.6	-58.4	178.5	0	0	0	113.1	L129 L130 A133 L139 Y141 E344 Y349 S350	L129-L346 HydrophobicContact CD1-CD1 4.28Å; L129-L346 HydrophobicContact CD2-CG 4.26Å; L129-L346 HydrophobicContact CG-CD1 4.48Å; L129-L346 HydrophobicContact CG-CD2 4.22Å; L129-L346 HydrophobicContact CG-CG 4.34Å; L130-L346 HydrophobicContact CD2-CD2 4.43Å; A133-L346 HydrophobicContact CB-CD2 3.73Å; L139-L346 VanDerWaalsContact O-CB 3.25Å; L139-L346 WeakPolarHBondContact O-CB 3.35Å; Y141-L346 HydrophobicContact CD2-CD1 4.13Å; Y141-L346 HydrophobicContact CG-CD1 4.45Å; E344-L346 PolarHBondContact O-N 3.44Å; L346-Y349 WeakPolarHBondContact O-CB 3.42Å; L346-Y349 PolarHBondContact O-N 2.72Å; L346-S350 PolarHBondContact O-N 3.11Å
347	P	87.1	Confident	90.6	Very high	53 Å²	53	35 Å²	35	34%	0.344	18%	0.176	S	C	.	.	H	α-helix	trans	-54.9	-49.9	169.4	-28.2	35.5	0	0	0	113	P343 E344 Y349 S350 E351	P343-P347 VanDerWaalsContact O-CD 3.22Å; P343-P347 WeakPolarHBondContact O-CD 3.14Å; E344-P347 WeakPolarHBondContact O-CD 3.33Å; P347-Y349 VanDerWaalsContact C-N 3.26Å; P347-Y349 PolarHBondContact O-N 3.49Å; P347-S350 WeakPolarHBondContact O-CB 3.48Å; P347-S350 PolarHBondContact O-N 3.05Å; P347-S350 PolarHBondContact O-OG 3.13Å; P347-E351 PolarHBondContact O-N 3Å
348	I	89.3	Confident	90.5	Very high	12 Å²	12	39.7 Å²	39.7	6%	0.062	20%	0.196	C	C	.	.	H	α-helix	trans	-60.9	-38.7	177.8	-67.1	168.8	0	0	0	110.8	N86 L87 E344 S350 E351 L352 M360	N86-I348 HydrophobicContact CB-CD1 3.97Å; N86-I348 HydrophobicContact CB-CG1 4.32Å; L87-I348 HydrophobicContact CB-CD1 3.94Å; L87-I348 HydrophobicContact CD1-CD1 4.06Å; E344-I348 HydrophobicContact CB-CD1 4.05Å; E344-I348 WeakPolarHBondContact O-CB 3.19Å; E344-I348 WeakPolarHBondContact O-CD1 3.43Å; E344-I348 WeakPolarHBondContact O-CG1 3.28Å; E344-I348 PolarHBondContact O-N 3.35Å; I348-S350 VanDerWaalsContact C-N 3.3Å; I348-S350 PolarHBondContact O-N 2.95Å; I348-E351 PolarHBondContact O-N 3.1Å; I348-L352 PolarHBondContact O-N 3.03Å; I348-L352 VanDerWaalsContact O-N 3.09Å; I348-M360 HydrophobicContact CB-CE 4.14Å; I348-M360 HydrophobicContact CG2-CE 3.88Å; I348-M360 HydrophobicContact CG2-SD 4.25Å
349	Y	90.5	Very high	90.5	Very high	32 Å²	32	41.4 Å²	41.4	13%	0.125	20%	0.203	C	C	.	.	H	α-helix	trans	-65	-34.2	176.6	-177	-140	0	0	0	112.8	L130 L139 V345 L346 P347 L352 R355 R357 M360	L130-Y349 HydrophobicContact CD2-CD1 4.05Å; L130-Y349 HydrophobicContact CD2-CG 4.33Å; L139-Y349 HydrophobicContact CD1-CD1 4.43Å; L139-Y349 HydrophobicContact CD2-CD1 3.54Å; L139-Y349 HydrophobicContact CD2-CE1 3.75Å; V345-Y349 VanDerWaalsContact O-CB 3.25Å; V345-Y349 WeakPolarHBondContact O-CB 3.31Å; V345-Y349 PolarHBondContact O-N 3.34Å; L346-Y349 WeakPolarHBondContact O-CB 3.42Å; L346-Y349 PolarHBondContact O-N 2.72Å; P347-Y349 VanDerWaalsContact C-N 3.26Å; P347-Y349 PolarHBondContact O-N 3.49Å; Y349-L352 HydrophobicContact CD2-CD2 4.33Å; Y349-R355 HydrophobicContact CD2-CB 4.23Å; Y349-R355 HydrophobicContact CE2-CB 3.77Å; Y349-R355 HydrophobicContact CE2-CG 4.37Å; Y349-R357 PolarHBondContact OH-N 3.12Å; Y349-M360 HydrophobicContact CD2-CB 3.52Å; Y349-M360 HydrophobicContact CD2-CG 3.75Å; Y349-M360 HydrophobicContact CD2-SD 4.34Å; Y349-M360 HydrophobicContact CE2-CB 3.92Å; Y349-M360 HydrophobicContact CG-CB 4.19Å; Y349-M360 HydrophobicContact CG-CG 3.95Å
350	S	86.8	Confident	90.4	Very high	45 Å²	45	41.4 Å²	41.4	32%	0.315	20%	0.203	S	C	.	.	H	α-helix	trans	-69.3	-32.7	177	77.2	0	0	0	0	112.8	L346 P347 I348	L346-S350 PolarHBondContact O-N 3.11Å; P347-S350 WeakPolarHBondContact O-CB 3.48Å; P347-S350 PolarHBondContact O-N 3.05Å; P347-S350 PolarHBondContact O-OG 3.13Å; I348-S350 VanDerWaalsContact C-N 3.3Å; I348-S350 PolarHBondContact O-N 2.95Å
351	E	86.5	Confident	90.5	Very high	104 Å²	104	42.3 Å²	42.3	49%	0.486	21%	0.207	S	C	.	.	H	α-helix	trans	-86.8	-14	179.3	-65.7	-172.7	170.8	0	0	113.9	G76 H77 A78 P347 I348 K353	G76-E351 CarbonylContact C-O 3.42Å; G76-E351 VanDerWaalsContact C-O 3.25Å; G76-E351 WeakPolarHBondContact CA-O 3.31Å; H77-E351 PolarHBondContact N-O 2.89Å; H77-E351 VanDerWaalsContact N-O 3.14Å; A78-E351 HydrophobicContact CB-CB 4.21Å; A78-E351 VanDerWaalsContact CB-O 3.31Å; A78-E351 WeakPolarHBondContact CB-O 3.41Å; A78-E351 PolarHBondContact N-O 3.16Å; P347-E351 PolarHBondContact O-N 3Å; I348-E351 PolarHBondContact O-N 3.1Å; E351-K353 PolarHBondContact O-N 3.3Å
352	L	89.1	Confident	90.6	Very high	1 Å²	1	49.4 Å²	49.4	1%	0.005	23%	0.233	C	C	.	.	B	Isolated β-bridge	trans	-63.4	123	-177.3	-179.1	64.5	0	0	0	111.5	S83 I348 Y349 R355 K359 M360	S83-L352 VanDerWaalsContact OG-CD1 3.25Å; S83-L352 WeakPolarHBondContact OG-CD1 3.34Å; I348-L352 PolarHBondContact O-N 3.03Å; I348-L352 VanDerWaalsContact O-N 3.09Å; Y349-L352 HydrophobicContact CD2-CD2 4.33Å; L352-R355 HydrophobicContact CB-CB 4.37Å; L352-R355 WeakPolarHBondContact O-CB 3.4Å; L352-R355 PolarHBondContact O-N 3.07Å; L352-K359 HydrophobicContact CD1-CD 4.48Å; L352-K359 HydrophobicContact CD2-CB 4.29Å; L352-K359 HydrophobicContact CD2-CD 4.07Å; L352-K359 HydrophobicContact CD2-CG 4.05Å; L352-K359 HydrophobicContact CG-CD 4.37Å; L352-M360 HydrophobicContact CD2-CB 4.28Å; L352-M360 HydrophobicContact CD2-SD 4.36Å
353	K	87.8	Confident	90.7	Very high	109 Å²	109	49.4 Å²	49.4	47%	0.474	23%	0.233	S	C	.	.	T	Hydrogen-bonded Turn	trans	-60.8	136.5	173.3	-174.4	-178.3	176.7	179.6	0	110.7	G76 A78 E351 R355 K359	G76-K353 WeakPolarHBondContact O-CA 3.11Å; A78-K353 WeakPolarHBondContact O-CB 3.44Å; A78-K353 PolarHBondContact O-N 2.89Å; E351-K353 PolarHBondContact O-N 3.3Å; K353-R355 VanDerWaalsContact C-N 3.34Å; K353-R355 PolarHBondContact O-N 3.32Å; K353-K359 PolarHBondContact O-NZ 3.42Å
354	D	87.8	Confident	91	Very high	114 Å²	114	48.8 Å²	48.8	61%	0.61	23%	0.229	S	C	*	.	T	Hydrogen-bonded Turn	trans	48.8	56.3	-177.4	-49.7	-46.5	0	0	0	110.9	S356 K359	D354-S356 PolarHBondContact O-N 3.33Å; D354-K359 WeakPolarHBondContact O-CD 3.34Å
355	R	86.3	Confident	91.4	Very high	83 Å²	83	50.6 Å²	50.6	31%	0.313	24%	0.24	S	C	.	.			trans	-62.6	130.9	-170.7	71.2	-175.3	-168.6	-170.1	3.5	111.2	L139 Y349 L352 K353	L139-R355 VanDerWaalsContact CD1-NH1 3.26Å; Y349-R355 HydrophobicContact CD2-CB 4.23Å; Y349-R355 HydrophobicContact CE2-CB 3.77Å; Y349-R355 HydrophobicContact CE2-CG 4.37Å; L352-R355 HydrophobicContact CB-CB 4.37Å; L352-R355 WeakPolarHBondContact O-CB 3.4Å; L352-R355 PolarHBondContact O-N 3.07Å; K353-R355 VanDerWaalsContact C-N 3.34Å; K353-R355 PolarHBondContact O-N 3.32Å
356	S	91.3	Very high	91.6	Very high	50 Å²	50	54.5 Å²	54.5	35%	0.35	26%	0.261	S	S	.	.			trans	-145.4	152.4	167.9	79.7	0	0	0	0	110.1	D354 K358 K359 M360	D354-S356 PolarHBondContact O-N 3.33Å; S356-K358 VanDerWaalsContact C-N 3.29Å; S356-K358 PolarHBondContact O-N 3.05Å; S356-K359 PolarHBondContact O-N 3.01Å; S356-K359 VanDerWaalsContact O-N 3.1Å; S356-K359 VanDerWaalsContact OG-CB 3.26Å; S356-K359 WeakPolarHBondContact OG-CB 3.46Å; S356-K359 PolarHBondContact OG-N 3.12Å; S356-K359 VanDerWaalsContact OG-N 3.14Å; S356-M360 PolarHBondContact O-N 3.35Å
357	R	90.7	Very high	91.9	Very high	60 Å²	60	54.5 Å²	54.5	23%	0.226	26%	0.26	C	S	.	.	H	α-helix	trans	-56.8	-46.2	179.4	-167.9	-170.9	79.8	-139.7	-0.3	111.2	L130 M131 Y349 K359 M360 Q361	L130-R357 HydrophobicContact CB-CG 4.06Å; M131-R357 PolarHBondContact SD-NH1 2.85Å; M131-R357 VanDerWaalsContact SD-NH1 3.37Å; Y349-R357 PolarHBondContact OH-N 3.12Å; R357-K359 VanDerWaalsContact C-N 3.29Å; R357-K359 PolarHBondContact O-N 3.09Å; R357-M360 PolarHBondContact O-N 3.43Å; R357-Q361 WeakPolarHBondContact O-CB 3.44Å; R357-Q361 PolarHBondContact O-N 3.37Å
358	K	92.6	Very high	92.4	Very high	110 Å²	110	52 Å²	52	48%	0.478	25%	0.245	S	C	.	.	H	α-helix	trans	-59.1	-39.4	177.6	-67.7	170.1	179.8	159.5	0	111.4	D18 S356 R362	D18-K358 IonicContact OD1-NZ 2.98Å; D18-K358 PolarHBondContact OD1-NZ 3.11Å; D18-K358 IonicContact OD2-NZ 2.61Å; S356-K358 VanDerWaalsContact C-N 3.29Å; S356-K358 PolarHBondContact O-N 3.05Å; K358-R362 WeakPolarHBondContact O-CG 3.49Å; K358-R362 PolarHBondContact O-N 3.32Å; K358-R362 VanDerWaalsContact O-N 3.13Å
359	K	93.8	Very high	92.8	Very high	36 Å²	36	55.9 Å²	55.9	16%	0.157	27%	0.265	C	S	.	.	H	α-helix	trans	-69.1	-46.2	177.6	-166.1	178.6	-175.2	177.5	0	111.7	F80 L352 K353 D354 S356 R357 Q361 R362 V363	F80-K359 HydrophobicContact CD2-CG 3.98Å; F80-K359 HydrophobicContact CE2-CG 4.38Å; L352-K359 HydrophobicContact CD1-CD 4.48Å; L352-K359 HydrophobicContact CD2-CB 4.29Å; L352-K359 HydrophobicContact CD2-CD 4.07Å; L352-K359 HydrophobicContact CD2-CG 4.05Å; L352-K359 HydrophobicContact CG-CD 4.37Å; K353-K359 PolarHBondContact O-NZ 3.42Å; D354-K359 WeakPolarHBondContact O-CD 3.34Å; S356-K359 PolarHBondContact O-N 3.01Å; S356-K359 VanDerWaalsContact O-N 3.1Å; S356-K359 VanDerWaalsContact OG-CB 3.26Å; S356-K359 WeakPolarHBondContact OG-CB 3.46Å; S356-K359 PolarHBondContact OG-N 3.12Å; S356-K359 VanDerWaalsContact OG-N 3.14Å; R357-K359 VanDerWaalsContact C-N 3.29Å; R357-K359 PolarHBondContact O-N 3.09Å; K359-Q361 PolarHBondContact O-N 3.44Å; K359-R362 WeakPolarHBondContact O-CB 3.44Å; K359-R362 PolarHBondContact O-N 2.86Å; K359-V363 WeakPolarHBondContact O-CG2 3.45Å; K359-V363 PolarHBondContact O-N 2.82Å
360	M	94.7	Very high	93	Very high	0 Å²	0	56.1 Å²	56.1	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-66.5	-35.6	177.8	-171.8	59.5	-165.4	0	0	112.8	L87 L130 V345 I348 Y349 L352 S356 R357 R362 V363 S364	L87-M360 HydrophobicContact CD2-CE 4.32Å; L130-M360 HydrophobicContact CD1-CB 4.18Å; L130-M360 HydrophobicContact CD1-CG 4Å; L130-M360 HydrophobicContact CD2-CB 4.43Å; L130-M360 HydrophobicContact CD2-CG 3.9Å; V345-M360 HydrophobicContact CB-CE 4.43Å; V345-M360 HydrophobicContact CG1-CE 3.94Å; V345-M360 WeakPolarHBondContact O-CE 3.31Å; I348-M360 HydrophobicContact CB-CE 4.14Å; I348-M360 HydrophobicContact CG2-CE 3.88Å; I348-M360 HydrophobicContact CG2-SD 4.25Å; Y349-M360 HydrophobicContact CD2-CB 3.52Å; Y349-M360 HydrophobicContact CD2-CG 3.75Å; Y349-M360 HydrophobicContact CD2-SD 4.34Å; Y349-M360 HydrophobicContact CE2-CB 3.92Å; Y349-M360 HydrophobicContact CG-CB 4.19Å; Y349-M360 HydrophobicContact CG-CG 3.95Å; L352-M360 HydrophobicContact CD2-CB 4.28Å; L352-M360 HydrophobicContact CD2-SD 4.36Å; S356-M360 PolarHBondContact O-N 3.35Å; R357-M360 PolarHBondContact O-N 3.43Å; M360-R362 VanDerWaalsContact C-N 3.33Å; M360-R362 PolarHBondContact O-N 3.09Å; M360-V363 WeakPolarHBondContact O-CB 3.47Å; M360-V363 PolarHBondContact O-N 3.28Å; M360-V363 HydrophobicContact SD-CB 4.23Å; M360-V363 HydrophobicContact SD-CG1 4.34Å; M360-S364 PolarHBondContact O-N 3.34Å; M360-S364 PolarHBondContact O-OG 3.32Å
361	Q	95.6	Very high	93.5	Very high	30 Å²	30	54.1 Å²	54.1	14%	0.14	26%	0.259	C	S	.	.	H	α-helix	trans	-62.8	-41.4	172.3	-169.2	66.4	55.3	0	0	111	L130 R357 K359 S364 N365	L130-Q361 HydrophobicContact CD1-CB 4.49Å; R357-Q361 WeakPolarHBondContact O-CB 3.44Å; R357-Q361 PolarHBondContact O-N 3.37Å; K359-Q361 PolarHBondContact O-N 3.44Å; Q361-S364 PolarHBondContact O-N 3.42Å; Q361-N365 PolarHBondContact NE2-OD1 2.91Å; Q361-N365 WeakPolarHBondContact O-CB 3.25Å; Q361-N365 PolarHBondContact O-N 3.02Å; Q361-N365 PolarHBondContact O-OD1 3.45Å
362	R	96.7	Very high	94	Very high	151 Å²	151	50.6 Å²	50.6	57%	0.57	24%	0.243	S	C	*	.	H	α-helix	trans	-63.2	-40.8	173.8	-75.6	-173	-67.2	163.6	-3.1	112.6	F80 K358 K359 M360 S364 N365 L366	F80-R362 HydrophobicContact CE2-CB 4.14Å; F80-R362 HydrophobicContact CZ-CB 4.34Å; K358-R362 WeakPolarHBondContact O-CG 3.49Å; K358-R362 PolarHBondContact O-N 3.32Å; K358-R362 VanDerWaalsContact O-N 3.13Å; K359-R362 WeakPolarHBondContact O-CB 3.44Å; K359-R362 PolarHBondContact O-N 2.86Å; M360-R362 VanDerWaalsContact C-N 3.33Å; M360-R362 PolarHBondContact O-N 3.09Å; R362-S364 VanDerWaalsContact C-N 3.28Å; R362-S364 PolarHBondContact O-N 3.25Å; R362-N365 PolarHBondContact O-N 3.42Å; R362-L366 WeakPolarHBondContact O-CB 3.31Å; R362-L366 PolarHBondContact O-N 3.14Å
363	V	96.6	Very high	94.4	Very high	0 Å²	0	54.9 Å²	54.9	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-56.9	-45.8	172.8	171.5	0	0	0	0	110.1	F80 V84 L87 K359 M360 S367	F80-V363 HydrophobicContact CD2-CG2 3.53Å; F80-V363 HydrophobicContact CE2-CB 4.43Å; F80-V363 HydrophobicContact CE2-CG2 3.39Å; F80-V363 HydrophobicContact CG-CG2 4.38Å; F80-V363 HydrophobicContact CZ-CG2 4.14Å; V84-V363 HydrophobicContact CG2-CB 4.29Å; V84-V363 HydrophobicContact CG2-CG1 3.93Å; V84-V363 HydrophobicContact CG2-CG2 4.26Å; L87-V363 HydrophobicContact CB-CG1 4.47Å; L87-V363 HydrophobicContact CD2-CG1 4.06Å; K359-V363 WeakPolarHBondContact O-CG2 3.45Å; K359-V363 PolarHBondContact O-N 2.82Å; M360-V363 WeakPolarHBondContact O-CB 3.47Å; M360-V363 PolarHBondContact O-N 3.28Å; M360-V363 HydrophobicContact SD-CB 4.23Å; M360-V363 HydrophobicContact SD-CG1 4.34Å; V363-S367 WeakPolarHBondContact O-CB 3.1Å; V363-S367 PolarHBondContact O-N 3.24Å; V363-S367 PolarHBondContact O-OG 3.27Å
364	S	96.9	Very high	94.7	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-67	-46.6	-179.3	-53.2	0	0	0	0	112.7	M360 Q361 R362 L366 S367 I368	M360-S364 PolarHBondContact O-N 3.34Å; M360-S364 PolarHBondContact O-OG 3.32Å; Q361-S364 PolarHBondContact O-N 3.42Å; R362-S364 VanDerWaalsContact C-N 3.28Å; R362-S364 PolarHBondContact O-N 3.25Å; S364-L366 PolarHBondContact O-N 3.03Å; S364-S367 PolarHBondContact O-N 3.45Å; S364-I368 WeakPolarHBondContact O-CB 3.41Å; S364-I368 WeakPolarHBondContact O-CG1 3.33Å; S364-I368 PolarHBondContact O-N 2.97Å
365	N	96.9	Very high	95.2	Very high	71 Å²	71	45.1 Å²	45.1	38%	0.38	22%	0.218	S	C	.	.	H	α-helix	trans	-58.8	-46.7	177.1	-67.4	7.6	0	0	0	111.5	L123 Q361 R362 L369	L123-N365 HydrophobicContact CD2-CB 4.39Å; L123-N365 VanDerWaalsContact CD2-OD1 3.32Å; L123-N365 WeakPolarHBondContact CD2-OD1 3.48Å; Q361-N365 PolarHBondContact NE2-OD1 2.91Å; Q361-N365 WeakPolarHBondContact O-CB 3.25Å; Q361-N365 PolarHBondContact O-N 3.02Å; Q361-N365 PolarHBondContact O-OD1 3.45Å; R362-N365 PolarHBondContact O-N 3.42Å; N365-L369 WeakPolarHBondContact O-CB 3.22Å; N365-L369 PolarHBondContact O-N 2.8Å
366	L	97.3	Very high	95.7	Very high	83 Å²	83	43 Å²	43	44%	0.435	21%	0.212	S	C	.	.	H	α-helix	trans	-67.5	-42	-179.8	-176.1	59.1	0	0	0	111.9	F80 V84 R362 S364 A370	F80-L366 HydrophobicContact CE1-CD2 4.21Å; V84-L366 HydrophobicContact CG1-CD2 4.31Å; V84-L366 HydrophobicContact CG1-CG 4.37Å; V84-L366 HydrophobicContact CG2-CD2 4.12Å; R362-L366 WeakPolarHBondContact O-CB 3.31Å; R362-L366 PolarHBondContact O-N 3.14Å; S364-L366 PolarHBondContact O-N 3.03Å; L366-A370 WeakPolarHBondContact O-CB 3.38Å; L366-A370 PolarHBondContact O-N 3.45Å
367	S	97.1	Very high	96	Very high	0 Å²	0	43.5 Å²	43.5	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-65.2	-48.6	179.4	-52.8	0	0	0	0	111.3	V84 V363 S364 L369 A370 M371	V84-S367 PolarHBondContact O-OG 3.48Å; V363-S367 WeakPolarHBondContact O-CB 3.1Å; V363-S367 PolarHBondContact O-N 3.24Å; V363-S367 PolarHBondContact O-OG 3.27Å; S364-S367 PolarHBondContact O-N 3.45Å; S367-L369 PolarHBondContact O-N 3.09Å; S367-A370 PolarHBondContact O-N 3.45Å; S367-M371 VanDerWaalsContact O-CG 3.3Å; S367-M371 WeakPolarHBondContact O-CG 3.45Å; S367-M371 PolarHBondContact O-N 2.84Å
368	I	96.7	Very high	96.2	Very high	2 Å²	2	40.6 Å²	40.6	1%	0.01	20%	0.2	C	C	.	.	H	α-helix	trans	-65	-39.6	179.3	-69.5	170.7	0	0	0	111.2	I91 A119 L123 F339 S364 M371 L372	I91-I368 HydrophobicContact CD1-CG1 3.63Å; A119-I368 HydrophobicContact CB-CG2 4.08Å; L123-I368 HydrophobicContact CD1-CG2 4.09Å; L123-I368 HydrophobicContact CD2-CB 4.05Å; L123-I368 HydrophobicContact CD2-CD1 3.53Å; L123-I368 HydrophobicContact CD2-CG1 4.29Å; L123-I368 HydrophobicContact CD2-CG2 4.34Å; L123-I368 HydrophobicContact CG-CB 4.22Å; L123-I368 HydrophobicContact CG-CD1 3.74Å; L123-I368 HydrophobicContact CG-CG2 3.96Å; F339-I368 HydrophobicContact CD1-CG2 4.37Å; F339-I368 HydrophobicContact CE1-CG2 4.15Å; S364-I368 WeakPolarHBondContact O-CB 3.41Å; S364-I368 WeakPolarHBondContact O-CG1 3.33Å; S364-I368 PolarHBondContact O-N 2.97Å; I368-M371 PolarHBondContact O-N 3.34Å; I368-L372 VanDerWaalsContact O-CB 3.27Å; I368-L372 WeakPolarHBondContact O-CB 3.23Å; I368-L372 PolarHBondContact O-N 2.86Å
369	L	97.2	Very high	96.3	Very high	93 Å²	93	35.4 Å²	35.4	49%	0.487	18%	0.177	S	C	.	.	H	α-helix	trans	-62.9	-45.8	175.4	178.5	63.8	0	0	0	111.8	N365 S367 M371 L372 I373	N365-L369 WeakPolarHBondContact O-CB 3.22Å; N365-L369 PolarHBondContact O-N 2.8Å; S367-L369 PolarHBondContact O-N 3.09Å; L369-M371 VanDerWaalsContact C-N 3.32Å; L369-M371 PolarHBondContact O-N 3.01Å; L369-L372 PolarHBondContact O-N 3.17Å; L369-I373 HydrophobicContact CD1-CD1 4.41Å; L369-I373 HydrophobicContact CG-CD1 4.39Å; L369-I373 WeakPolarHBondContact O-CG1 3.43Å; L369-I373 PolarHBondContact O-N 3.1Å; L369-I373 VanDerWaalsContact O-N 3.13Å
370	A	95.8	Very high	96.5	Very high	37 Å²	37	35.9 Å²	35.9	31%	0.306	18%	0.181	S	C	.	.	H	α-helix	trans	-60.2	-44.2	177.2	0	0	0	0	0	111.2	L366 S367 I373 M374	L366-A370 WeakPolarHBondContact O-CB 3.38Å; L366-A370 PolarHBondContact O-N 3.45Å; S367-A370 PolarHBondContact O-N 3.45Å; A370-I373 PolarHBondContact O-N 2.98Å; A370-M374 PolarHBondContact O-N 2.71Å; A370-M374 VanDerWaalsContact O-N 3.13Å
371	M	96.1	Very high	96.5	Very high	2 Å²	2	38.4 Å²	38.4	1%	0.01	19%	0.192	C	C	.	.	H	α-helix	trans	-68.4	-39.6	178.1	-64.4	-51.1	99.1	0	0	112.2	I91 M92 L233 S367 I368 L369 I373 M374 Y375	I91-M371 HydrophobicContact CB-CB 4.48Å; I91-M371 HydrophobicContact CB-CG 3.76Å; I91-M371 HydrophobicContact CD1-CG 4.2Å; I91-M371 HydrophobicContact CG2-CB 3.7Å; I91-M371 HydrophobicContact CG2-CG 3.52Å; M92-M371 HydrophobicContact CB-SD 3.8Å; L233-M371 HydrophobicContact CD1-CE 3.87Å; S367-M371 VanDerWaalsContact O-CG 3.3Å; S367-M371 WeakPolarHBondContact O-CG 3.45Å; S367-M371 PolarHBondContact O-N 2.84Å; I368-M371 PolarHBondContact O-N 3.34Å; L369-M371 VanDerWaalsContact C-N 3.32Å; L369-M371 PolarHBondContact O-N 3.01Å; M371-I373 VanDerWaalsContact C-N 3.28Å; M371-I373 PolarHBondContact O-N 3.42Å; M371-M374 HydrophobicContact CE-CE 3.18Å; M371-M374 HydrophobicContact CE-SD 4.43Å; M371-M374 PolarHBondContact O-N 3.1Å; M371-M374 HydrophobicContact SD-CE 3.26Å; M371-M374 WeakPolarHBondContact SD-CE 3.38Å; M371-Y375 HydrophobicContact CB-CE2 4.33Å; M371-Y375 WeakPolarHBondContact O-CB 3.2Å; M371-Y375 PolarHBondContact O-N 2.92Å
372	L	97.1	Very high	96.4	Very high	31 Å²	31	37 Å²	37	16%	0.162	19%	0.185	C	C	.	.	H	α-helix	trans	-55.5	-44.7	175.5	177.5	67.7	0	0	0	111.3	L115 V116 A119 F339 I368 L369 M376	L115-L372 HydrophobicContact CD2-CD1 3.61Å; L115-L372 HydrophobicContact CG-CD1 3.78Å; V116-L372 HydrophobicContact CG2-CD1 4.39Å; A119-L372 HydrophobicContact CB-CD1 4.03Å; A119-L372 HydrophobicContact CB-CD2 4.47Å; F339-L372 HydrophobicContact CZ-CB 4.45Å; F339-L372 HydrophobicContact CZ-CD1 4.07Å; I368-L372 VanDerWaalsContact O-CB 3.27Å; I368-L372 WeakPolarHBondContact O-CB 3.23Å; I368-L372 PolarHBondContact O-N 2.86Å; L369-L372 PolarHBondContact O-N 3.17Å; L372-M376 HydrophobicContact CD1-CG 4.48Å; L372-M376 WeakPolarHBondContact O-CB 3.46Å; L372-M376 WeakPolarHBondContact O-CG 3.4Å; L372-M376 PolarHBondContact O-N 3.49Å
373	I	96.8	Very high	96.3	Very high	91 Å²	91	29.8 Å²	29.8	47%	0.467	16%	0.158	S	C	.	.	H	α-helix	trans	-64	-49.8	177.3	-66.6	167.6	0	0	0	110.5	L369 A370 M371 Y375 M376 L377	L369-I373 HydrophobicContact CD1-CD1 4.41Å; L369-I373 HydrophobicContact CG-CD1 4.39Å; L369-I373 WeakPolarHBondContact O-CG1 3.43Å; L369-I373 PolarHBondContact O-N 3.1Å; L369-I373 VanDerWaalsContact O-N 3.13Å; A370-I373 PolarHBondContact O-N 2.98Å; M371-I373 VanDerWaalsContact C-N 3.28Å; M371-I373 PolarHBondContact O-N 3.42Å; I373-Y375 VanDerWaalsContact C-N 3.31Å; I373-Y375 PolarHBondContact O-N 3.45Å; I373-M376 PolarHBondContact O-N 3.3Å; I373-L377 HydrophobicContact CG2-CD1 3.82Å; I373-L377 HydrophobicContact CG2-CG 4.44Å; I373-L377 VanDerWaalsContact O-CG 3.3Å; I373-L377 WeakPolarHBondContact O-CG 3.39Å; I373-L377 PolarHBondContact O-N 2.68Å
374	M	95.5	Very high	96.1	Very high	18 Å²	18	31.6 Å²	31.6	9%	0.089	17%	0.168	C	C	.	.	H	α-helix	trans	-62.7	-39.7	179.9	-68.9	-163.2	-46.3	0	0	112.4	M92 L233 V237 L240 A370 M371 L377 S378	M92-M374 HydrophobicContact CE-CE 3.33Å; M92-M374 HydrophobicContact CE-SD 4.26Å; M92-M374 HydrophobicContact SD-CE 3.88Å; L233-M374 HydrophobicContact CD1-CE 3.81Å; L233-M374 HydrophobicContact CD1-SD 4.36Å; V237-M374 HydrophobicContact CG2-SD 3.91Å; L240-M374 HydrophobicContact CD2-CB 4.34Å; L240-M374 HydrophobicContact CD2-CG 4.18Å; A370-M374 PolarHBondContact O-N 2.71Å; A370-M374 VanDerWaalsContact O-N 3.13Å; M371-M374 HydrophobicContact CE-CE 3.18Å; M371-M374 HydrophobicContact CE-SD 4.43Å; M371-M374 PolarHBondContact O-N 3.1Å; M371-M374 HydrophobicContact SD-CE 3.26Å; M371-M374 WeakPolarHBondContact SD-CE 3.38Å; M374-L377 PolarHBondContact O-N 3.41Å; M374-S378 WeakPolarHBondContact O-CB 3.14Å; M374-S378 PolarHBondContact O-N 3.14Å
375	Y	97.1	Very high	95.7	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-65	-45.6	177.1	-75.3	-2.7	0	0	0	112.2	I91 M92 I96 L99 A338 F339 M371 I373 A379	I91-Y375 HydrophobicContact CG2-CE2 4.13Å; I91-Y375 PolarHBondContact O-OH 3.22Å; M92-Y375 VanDerWaalsContact C-OH 3.3Å; M92-Y375 WeakPolarHBondContact CA-OH 3.41Å; M92-Y375 PolarHBondContact N-OH 2.69Å; M92-Y375 PolarHBondContact O-OH 2.98Å; I96-Y375 HydrophobicContact CB-CD1 4.21Å; I96-Y375 HydrophobicContact CB-CE1 3.88Å; I96-Y375 HydrophobicContact CD1-CD1 4.3Å; I96-Y375 HydrophobicContact CD1-CE1 4.46Å; I96-Y375 HydrophobicContact CG1-CD1 4.05Å; I96-Y375 HydrophobicContact CG1-CE1 4.2Å; L99-Y375 HydrophobicContact CD1-CD1 3.52Å; L99-Y375 HydrophobicContact CD1-CD2 3.86Å; L99-Y375 HydrophobicContact CD1-CE1 4.2Å; L99-Y375 HydrophobicContact CD1-CE2 4.49Å; L99-Y375 HydrophobicContact CD1-CG 3.3Å; A338-Y375 HydrophobicContact CB-CE2 3.95Å; A338-Y375 WeakPolarHBondContact O-CE2 3.12Å; A338-Y375 PolarHBondContact O-OH 3.27Å; A338-Y375 VanDerWaalsContact O-OH 3.1Å; F339-Y375 HydrophobicContact CD1-CE2 4.41Å; F339-Y375 HydrophobicContact CE1-CD2 4.03Å; F339-Y375 HydrophobicContact CE1-CE2 4.1Å; F339-Y375 HydrophobicContact CE2-CD2 4.04Å; F339-Y375 HydrophobicContact CE2-CE2 4.4Å; F339-Y375 AromaticContact CZ-CD2 3.65Å; F339-Y375 HydrophobicContact CZ-CD2 3.65Å; F339-Y375 HydrophobicContact CZ-CE2 4.1Å; M371-Y375 HydrophobicContact CB-CE2 4.33Å; M371-Y375 WeakPolarHBondContact O-CB 3.2Å; M371-Y375 PolarHBondContact O-N 2.92Å; I373-Y375 VanDerWaalsContact C-N 3.31Å; I373-Y375 PolarHBondContact O-N 3.45Å; Y375-A379 WeakPolarHBondContact O-CB 3.28Å; Y375-A379 PolarHBondContact O-N 2.8Å
376	M	97.3	Very high	95.3	Very high	38 Å²	38	28.4 Å²	28.4	19%	0.187	15%	0.151	C	C	.	.	H	α-helix	trans	-60.2	-47.6	174.8	-80.1	-53.6	-53	0	0	111.8	M103 F111 T112 L115 L372 I373 L380	M103-M376 HydrophobicContact CE-CE 4.36Å; F111-M376 HydrophobicContact CD1-SD 4.3Å; F111-M376 HydrophobicContact CE1-SD 4.06Å; T112-M376 HydrophobicContact CG2-CE 3.83Å; T112-M376 HydrophobicContact CG2-SD 4.23Å; T112-M376 VanDerWaalsContact OG1-CE 3.28Å; T112-M376 WeakPolarHBondContact OG1-CE 3.46Å; L115-M376 HydrophobicContact CB-SD 4.17Å; L115-M376 HydrophobicContact CD2-CB 4.42Å; L115-M376 HydrophobicContact CD2-CG 3.49Å; L115-M376 VanDerWaalsContact CD2-CG 3.49Å; L115-M376 HydrophobicContact CD2-SD 3.18Å; L115-M376 WeakPolarHBondContact CD2-SD 3.32Å; L115-M376 HydrophobicContact CG-SD 4.26Å; L372-M376 HydrophobicContact CD1-CG 4.48Å; L372-M376 WeakPolarHBondContact O-CB 3.46Å; L372-M376 WeakPolarHBondContact O-CG 3.4Å; L372-M376 PolarHBondContact O-N 3.49Å; I373-M376 PolarHBondContact O-N 3.3Å; M376-L380 WeakPolarHBondContact O-CB 3.12Å; M376-L380 PolarHBondContact O-N 3.18Å
377	L	96.9	Very high	95	Very high	60 Å²	60	25.5 Å²	25.5	31%	0.314	13%	0.134	S	C	.	.	H	α-helix	trans	-66.7	-47.1	-179.1	-64.7	170.9	0	0	0	111.1	L240 I373 M374 A379 L380 F381	L240-L377 HydrophobicContact CD1-CB 3.75Å; L240-L377 HydrophobicContact CD2-CB 4.16Å; L240-L377 HydrophobicContact CD2-CD1 4.12Å; I373-L377 HydrophobicContact CG2-CD1 3.82Å; I373-L377 HydrophobicContact CG2-CG 4.44Å; I373-L377 VanDerWaalsContact O-CG 3.3Å; I373-L377 WeakPolarHBondContact O-CG 3.39Å; I373-L377 PolarHBondContact O-N 2.68Å; M374-L377 PolarHBondContact O-N 3.41Å; L377-A379 PolarHBondContact O-N 3.16Å; L377-L380 PolarHBondContact O-N 3.49Å; L377-F381 HydrophobicContact CB-CD2 4.38Å; L377-F381 HydrophobicContact CD2-CD2 4.44Å; L377-F381 HydrophobicContact CD2-CE2 3.9Å; L377-F381 WeakPolarHBondContact O-CB 3.38Å; L377-F381 VanDerWaalsContact O-CD2 3.25Å; L377-F381 WeakPolarHBondContact O-CD2 3.39Å; L377-F381 PolarHBondContact O-N 2.99Å
378	S	95.1	Very high	94.4	Very high	0 Å²	0	29 Å²	29	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-60.5	-45.3	177.9	-172.2	0	0	0	0	111.6	S100 M374 G382	S100-S378 PolarHBondContact OG-O 2.74Å; S100-S378 VanDerWaalsContact OG-O 3.05Å; M374-S378 WeakPolarHBondContact O-CB 3.14Å; M374-S378 PolarHBondContact O-N 3.14Å; S378-G382 PolarHBondContact O-N 3.47Å
379	A	96.3	Very high	93.9	Very high	0 Å²	0	31.4 Å²	31.4	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-62.3	-49	177.7	0	0	0	0	0	111.2	L99 S100 M103 F111 Y375 L377 Y383	L99-A379 HydrophobicContact CB-CB 3.87Å; S100-A379 PolarHBondContact OG-O 3.24Å; M103-A379 HydrophobicContact CB-CB 4.43Å; M103-A379 HydrophobicContact CE-CB 3.66Å; M103-A379 HydrophobicContact SD-CB 4.47Å; F111-A379 HydrophobicContact CD1-CB 4.42Å; F111-A379 HydrophobicContact CE1-CB 3.49Å; F111-A379 VanDerWaalsContact CE1-CB 3.49Å; F111-A379 HydrophobicContact CZ-CB 3.55Å; Y375-A379 WeakPolarHBondContact O-CB 3.28Å; Y375-A379 PolarHBondContact O-N 2.8Å; L377-A379 PolarHBondContact O-N 3.16Å; A379-Y383 WeakPolarHBondContact O-CB 3.26Å; A379-Y383 PolarHBondContact O-N 3.37Å
380	L	96.2	Very high	93.5	Very high	47 Å²	47	27.4 Å²	27.4	25%	0.246	14%	0.143	C	C	.	.	H	α-helix	trans	-63.1	-53.8	-177.9	-178.3	64.9	0	0	0	112.3	M103 I108 M376 L377 Y383 L384	M103-L380 HydrophobicContact CE-CB 4.19Å; M103-L380 HydrophobicContact SD-CB 4.42Å; M103-L380 HydrophobicContact SD-CD1 4.24Å; I108-L380 HydrophobicContact CD1-CD1 4.21Å; I108-L380 HydrophobicContact CG1-CD1 4.47Å; I108-L380 HydrophobicContact CG2-CD1 4.33Å; M376-L380 WeakPolarHBondContact O-CB 3.12Å; M376-L380 PolarHBondContact O-N 3.18Å; L377-L380 PolarHBondContact O-N 3.49Å; L380-Y383 PolarHBondContact O-N 2.82Å; L380-L384 HydrophobicContact CD1-CD1 3.85Å; L380-L384 HydrophobicContact CD1-CG 4.11Å; L380-L384 HydrophobicContact CG-CD1 3.94Å; L380-L384 HydrophobicContact CG-CG 4.47Å; L380-L384 WeakPolarHBondContact O-CB 3.34Å; L380-L384 VanDerWaalsContact O-CG 3.25Å; L380-L384 WeakPolarHBondContact O-CG 3.31Å; L380-L384 PolarHBondContact O-N 2.93Å
381	F	95.2	Very high	93.3	Very high	53 Å²	53	28.1 Å²	28.1	23%	0.232	14%	0.14	C	C	.	.	H	α-helix	trans	-72	-33.2	-177.1	-73.2	-78.8	0	0	0	112.1	I243 I244 K247 L377 T385	I243-F381 HydrophobicContact CG2-CB 3.85Å; I244-F381 HydrophobicContact CB-CG 4.49Å; I244-F381 HydrophobicContact CD1-CD2 4.16Å; I244-F381 HydrophobicContact CD1-CE2 4.18Å; I244-F381 HydrophobicContact CG1-CB 4.26Å; I244-F381 HydrophobicContact CG1-CD1 4.28Å; I244-F381 HydrophobicContact CG1-CD2 3.56Å; I244-F381 HydrophobicContact CG1-CE2 3.9Å; I244-F381 HydrophobicContact CG1-CG 3.78Å; I244-F381 HydrophobicContact CG1-CZ 4.41Å; I244-F381 HydrophobicContact CG2-CD1 4.41Å; I244-F381 HydrophobicContact CG2-CE1 4.19Å; I244-F381 HydrophobicContact CG2-CZ 4.27Å; K247-F381 HydrophobicContact CB-CD1 4.14Å; K247-F381 HydrophobicContact CG-CD1 3.98Å; L377-F381 HydrophobicContact CB-CD2 4.38Å; L377-F381 HydrophobicContact CD2-CD2 4.44Å; L377-F381 HydrophobicContact CD2-CE2 3.9Å; L377-F381 WeakPolarHBondContact O-CB 3.38Å; L377-F381 VanDerWaalsContact O-CD2 3.25Å; L377-F381 WeakPolarHBondContact O-CD2 3.39Å; L377-F381 PolarHBondContact O-N 2.99Å; F381-T385 WeakPolarHBondContact O-CB 3.15Å; F381-T385 PolarHBondContact O-N 3.25Å; F381-T385 PolarHBondContact O-OG1 3.11Å
382	G	93.9	Very high	92.8	Very high	0 Å²	0	29 Å²	29	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-65.3	-43	170.8	0	0	0	0	0	112.4	S100 S378 T385	S100-G382 WeakPolarHBondContact OG-CA 3.31Å; S378-G382 PolarHBondContact O-N 3.47Å; G382-T385 PolarHBondContact O-N 2.92Å
383	Y	94.6	Very high	92.4	Very high	0 Å²	0	28 Å²	28	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-63.5	-51.3	174.8	170	-113.3	0	0	0	111.9	M103 A104 I108 P319 K320 A379 L380 T385 F386 Y387	M103-Y383 HydrophobicContact CG-CD1 4.12Å; M103-Y383 HydrophobicContact CG-CG 3.98Å; M103-Y383 HydrophobicContact SD-CD1 3.77Å; M103-Y383 HydrophobicContact SD-CG 3.9Å; A104-Y383 HydrophobicContact CB-CD2 3.79Å; A104-Y383 HydrophobicContact CB-CE2 4.04Å; I108-Y383 HydrophobicContact CD1-CD1 4.22Å; I108-Y383 HydrophobicContact CD1-CE1 3.88Å; I108-Y383 HydrophobicContact CG1-CD1 3.92Å; I108-Y383 HydrophobicContact CG1-CE1 3.68Å; P319-Y383 HydrophobicContact CB-CE1 4.46Å; K320-Y383 PolarHBondContact N-OH 3.4Å; A379-Y383 WeakPolarHBondContact O-CB 3.26Å; A379-Y383 PolarHBondContact O-N 3.37Å; L380-Y383 PolarHBondContact O-N 2.82Å; Y383-T385 PolarHBondContact O-N 3.01Å; Y383-F386 PolarHBondContact O-N 3.36Å; Y383-F386 VanDerWaalsContact O-N 3.14Å; Y383-Y387 WeakPolarHBondContact O-CA 2.99Å; Y383-Y387 PolarHBondContact O-N 3.48Å
384	L	92.3	Very high	92.1	Very high	37 Å²	37	23.7 Å²	23.7	19%	0.194	12%	0.12	C	C	.	.	H	α-helix	trans	-63.8	-14.3	-179.6	-68.9	176.8	0	0	0	113.5	I108 K247 P319 L380 Y387	I108-L384 HydrophobicContact CD1-CD2 4.43Å; K247-L384 HydrophobicContact CD-CB 3.97Å; K247-L384 WeakPolarHBondContact CD-O 3.47Å; K247-L384 WeakPolarHBondContact CE-O 3.44Å; P319-L384 HydrophobicContact CB-CD2 4.21Å; L380-L384 HydrophobicContact CD1-CD1 3.85Å; L380-L384 HydrophobicContact CD1-CG 4.11Å; L380-L384 HydrophobicContact CG-CD1 3.94Å; L380-L384 HydrophobicContact CG-CG 4.47Å; L380-L384 WeakPolarHBondContact O-CB 3.34Å; L380-L384 VanDerWaalsContact O-CG 3.25Å; L380-L384 WeakPolarHBondContact O-CG 3.31Å; L380-L384 PolarHBondContact O-N 2.93Å; L384-Y387 HydrophobicContact CD2-CE1 4.34Å; L384-Y387 WeakPolarHBondContact O-CE2 3.49Å
385	T	89.3	Confident	91.7	Very high	5 Å²	5	22.9 Å²	22.9	3%	0.031	12%	0.116	C	C	.	.	H	α-helix	trans	-80.3	-36.2	176.7	-59.1	0	0	0	0	111.8	K247 L250 F381 G382 Y383 F398	K247-T385 WeakPolarHBondContact CD-OG1 3.33Å; L250-T385 HydrophobicContact CD1-CG2 3.86Å; F381-T385 WeakPolarHBondContact O-CB 3.15Å; F381-T385 PolarHBondContact O-N 3.25Å; F381-T385 PolarHBondContact O-OG1 3.11Å; G382-T385 PolarHBondContact O-N 2.92Å; Y383-T385 PolarHBondContact O-N 3.01Å; T385-F398 HydrophobicContact CG2-CE1 4.11Å; T385-F398 HydrophobicContact CG2-CZ 4.14Å
386	F	88.1	Confident	91.1	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-127.1	-7.5	-171.4	-54.8	-73.1	0	0	0	115	L254 F256 M257 Y383 D388 F389 V390 L394 T397 F398 V401	L254-F386 HydrophobicContact CD1-CD1 3.77Å; L254-F386 HydrophobicContact CD1-CE1 3.95Å; F256-F386 HydrophobicContact CE1-CD1 4.34Å; F256-F386 HydrophobicContact CZ-CD1 4.11Å; M257-F386 VanDerWaalsContact CE-O 3.25Å; M257-F386 WeakPolarHBondContact CE-O 3.45Å; Y383-F386 PolarHBondContact O-N 3.36Å; Y383-F386 VanDerWaalsContact O-N 3.14Å; F386-D388 PolarHBondContact O-N 3.45Å; F386-F389 WeakPolarHBondContact O-CB 3.32Å; F386-F389 PolarHBondContact O-N 3.03Å; F386-V390 HydrophobicContact CB-CG2 3.76Å; F386-L394 HydrophobicContact CD2-CD1 4.14Å; F386-L394 HydrophobicContact CE2-CD1 4.04Å; F386-T397 HydrophobicContact CB-CG2 4.08Å; F386-T397 HydrophobicContact CD1-CG2 3.65Å; F386-T397 HydrophobicContact CD2-CG2 3.55Å; F386-T397 HydrophobicContact CE1-CG2 3.84Å; F386-T397 HydrophobicContact CE2-CG2 3.75Å; F386-T397 HydrophobicContact CG-CG2 3.48Å; F386-T397 VanDerWaalsContact CG-CG2 3.48Å; F386-T397 HydrophobicContact CZ-CG2 3.89Å; F386-F398 HydrophobicContact CE2-CD1 4.16Å; F386-F398 AromaticContact CE2-CD2 3.81Å; F386-F398 HydrophobicContact CE2-CD2 3.81Å; F386-F398 AromaticContact CE2-CE1 3.99Å; F386-F398 HydrophobicContact CE2-CE1 3.99Å; F386-F398 AromaticContact CE2-CE2 3.64Å; F386-F398 HydrophobicContact CE2-CE2 3.64Å; F386-F398 HydrophobicContact CE2-CG 4.06Å; F386-F398 AromaticContact CE2-CZ 3.72Å; F386-F398 HydrophobicContact CE2-CZ 3.72Å; F386-F398 HydrophobicContact CZ-CB 4.41Å; F386-F398 AromaticContact CZ-CD1 3.59Å; F386-F398 HydrophobicContact CZ-CD1 3.59Å; F386-F398 AromaticContact CZ-CD2 3.98Å; F386-F398 HydrophobicContact CZ-CD2 3.98Å; F386-F398 AromaticContact CZ-CE1 3.69Å; F386-F398 HydrophobicContact CZ-CE1 3.69Å; F386-F398 HydrophobicContact CZ-CE2 4.09Å; F386-F398 AromaticContact CZ-CG 3.72Å; F386-F398 HydrophobicContact CZ-CG 3.72Å; F386-F398 AromaticContact CZ-CZ 3.94Å; F386-F398 HydrophobicContact CZ-CZ 3.94Å; F386-V401 HydrophobicContact CE1-CG2 3.89Å
387	Y	89.8	Confident	90.5	Very high	22 Å²	22	24 Å²	24	9%	0.086	12%	0.121	C	C	.	.	G	3₁₀ helix	trans	51	-118.2	-179.8	-63.6	-95.5	0	0	0	112.7	C252 C317 P319 Y383 L384 F389 V390	C252-Y387 HydrophobicContact CB-CE2 4.35Å; C252-Y387 VanDerWaalsContact SG-CE2 3.56Å; C317-Y387 VanDerWaalsContact C-CE1 3.47Å; C317-Y387 HydrophobicContact CB-CE2 4.47Å; C317-Y387 VanDerWaalsContact O-CE1 3.23Å; C317-Y387 WeakPolarHBondContact O-CE1 3.43Å; C317-Y387 PolarHBondContact O-OH 2.81Å; P319-Y387 HydrophobicContact CB-CE1 4.36Å; Y383-Y387 WeakPolarHBondContact O-CA 2.99Å; Y383-Y387 PolarHBondContact O-N 3.48Å; L384-Y387 HydrophobicContact CD2-CE1 4.34Å; L384-Y387 WeakPolarHBondContact O-CE2 3.49Å; Y387-F389 PolarHBondContact O-N 3.13Å; Y387-V390 WeakPolarHBondContact O-CG2 3.48Å
388	D	84.8	Confident	90	Very high	74 Å²	74	21.4 Å²	21.4	40%	0.396	11%	0.107	S	C	.	.	G	3₁₀ helix	trans	-73.4	-11.5	-178.4	-64.6	-40.3	0	0	0	113.2	K320 F386	K320-D388 WeakPolarHBondContact CE-OD2 3.25Å; K320-D388 IonicContact NZ-OD1 2.75Å; K320-D388 PolarHBondContact NZ-OD1 2.82Å; K320-D388 IonicContact NZ-OD2 3.77Å; K320-D388 PolarHBondContact NZ-OD2 2.99Å; F386-D388 PolarHBondContact O-N 3.45Å
389	F	86.7	Confident	89.3	Confident	52 Å²	52	22.1 Å²	22.1	23%	0.228	11%	0.111	C	C	.	.	G	3₁₀ helix	trans	-94.9	13.2	-175.6	-57.8	-87.2	0	0	0	113.7	F256 M257 M316 F386 Y387 E391	F256-F389 HydrophobicContact CE2-CB 4.02Å; F256-F389 HydrophobicContact CE2-CD1 4.47Å; F256-F389 HydrophobicContact CE2-CG 4.31Å; F256-F389 HydrophobicContact CZ-CB 4.3Å; M257-F389 HydrophobicContact CB-CD2 4.46Å; M257-F389 HydrophobicContact CB-CE2 3.99Å; M257-F389 HydrophobicContact CB-CZ 4.09Å; M257-F389 HydrophobicContact CE-CB 4.34Å; M257-F389 HydrophobicContact CE-CD2 3.5Å; M257-F389 HydrophobicContact CE-CE2 4.17Å; M257-F389 HydrophobicContact CE-CG 4.23Å; M257-F389 HydrophobicContact CG-CD2 3.79Å; M257-F389 HydrophobicContact CG-CE2 3.81Å; M257-F389 HydrophobicContact CG-CG 4.26Å; M257-F389 HydrophobicContact CG-CZ 4.3Å; M257-F389 HydrophobicContact SD-CD2 3.71Å; M257-F389 HydrophobicContact SD-CE2 3.74Å; M316-F389 HydrophobicContact CE-CE2 4.05Å; M316-F389 HydrophobicContact CE-CZ 4.03Å; F386-F389 WeakPolarHBondContact O-CB 3.32Å; F386-F389 PolarHBondContact O-N 3.03Å; Y387-F389 PolarHBondContact O-N 3.13Å; F389-E391 PolarHBondContact O-N 3.18Å
390	V	89.8	Confident	88.3	Confident	9 Å²	9	27.2 Å²	27.2	6%	0.055	13%	0.134	C	C	.	.			trans	-70.1	125	175.6	-177.5	0	0	0	0	109.8	Y101 A104 F386 Y387 L394	Y101-V390 WeakPolarHBondContact CD2-O 3.49Å; A104-V390 HydrophobicContact CB-CB 4.1Å; A104-V390 HydrophobicContact CB-CG2 4.23Å; F386-V390 HydrophobicContact CB-CG2 3.76Å; Y387-V390 WeakPolarHBondContact O-CG2 3.48Å; V390-L394 HydrophobicContact CG1-CD1 4.48Å
391	E	89.8	Confident	87.3	Confident	51 Å²	51	27.1 Å²	27.1	24%	0.238	13%	0.134	C	C	.	.			trans	-85.5	165.7	173.2	-66	177	132.6	0	0	111.9	Y101 F389 E393 H396 T397 K400	Y101-E391 WeakPolarHBondContact CB-O 3.1Å; F389-E391 PolarHBondContact O-N 3.18Å; E391-E393 PolarHBondContact O-N 3.29Å; E391-H396 IonicContact OE1-CE1 2.81Å; E391-H396 IonicContact OE1-ND1 3.87Å; E391-H396 IonicContact OE2-CE1 3.85Å; E391-H396 PolarHBondContact OE2-CE1 3.44Å; E391-H396 IonicContact OE2-CG 2.65Å; E391-H396 IonicContact OE2-ND1 3.47Å; E391-H396 PolarHBondContact OE2-ND1 3.04Å; E391-T397 WeakPolarHBondContact CB-OG1 3.41Å; E391-T397 PolarHBondContact N-OG1 3.35Å; E391-K400 VanDerWaalsContact CD-CE 3.46Å; E391-K400 WeakPolarHBondContact OE1-CE 3.36Å; E391-K400 IonicContact OE1-NZ 3.72Å; E391-K400 PolarHBondContact OE1-NZ 3.35Å; E391-K400 WeakPolarHBondContact OE2-CE 3.47Å; E391-K400 IonicContact OE2-NZ 3.71Å
392	A	86.9	Confident	86.3	Confident	21 Å²	21	28 Å²	28	17%	0.174	14%	0.137	C	C	.	.	S	Bend	trans	-57	-20.5	178.8	0	0	0	0	0	113.8	Y101 I470 R471	Y101-A392 HydrophobicContact CD2-CB 4.45Å; Y101-A392 HydrophobicContact CG-CB 4.39Å; A392-I470 HydrophobicContact CB-CG2 3.95Å; A392-R471 HydrophobicContact CB-CB 3.97Å
393	E	88.8	Confident	85	Confident	10 Å²	10	34.1 Å²	34.1	5%	0.047	16%	0.164	C	C	.	.	S	Bend	trans	-119.9	116	171.2	-178	167.9	-161.9	0	0	110.3	E391 L395 H396 T397 I470	E391-E393 PolarHBondContact O-N 3.29Å; E393-L395 PolarHBondContact O-N 3.47Å; E393-H396 HydrophobicContact CB-CB 4.15Å; E393-H396 HydrophobicContact CG-CB 4.18Å; E393-H396 PolarHBondContact O-N 2.81Å; E393-T397 PolarHBondContact O-N 2.92Å; E393-T397 PolarHBondContact O-OG1 3.09Å; E393-I470 HydrophobicContact CB-CG2 4.48Å
394	L	90.3	Very high	83.9	Confident	0 Å²	0	38.2 Å²	38.2	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-63.4	-40.1	-175	-176.9	63.7	0	0	0	113.3	L97 F239 I243 F386 V390 H396 T397 F398	L97-L394 PolarHBondContact O-N 3.24Å; F239-L394 HydrophobicContact CE2-CD2 4.41Å; F239-L394 HydrophobicContact CZ-CD2 4.01Å; I243-L394 HydrophobicContact CD1-CD2 3.84Å; I243-L394 HydrophobicContact CG1-CD2 4.39Å; F386-L394 HydrophobicContact CD2-CD1 4.14Å; F386-L394 HydrophobicContact CE2-CD1 4.04Å; V390-L394 HydrophobicContact CG1-CD1 4.48Å; L394-H396 VanDerWaalsContact C-N 3.32Å; L394-H396 PolarHBondContact O-N 3.44Å; L394-T397 WeakPolarHBondContact O-CB 3.48Å; L394-T397 PolarHBondContact O-N 3.01Å; L394-T397 VanDerWaalsContact O-N 3.14Å; L394-F398 HydrophobicContact CD1-CD2 4.4Å; L394-F398 HydrophobicContact CD1-CE2 4.02Å; L394-F398 HydrophobicContact CD2-CE2 4.32Å; L394-F398 HydrophobicContact CG-CD2 4.17Å; L394-F398 HydrophobicContact CG-CE2 3.92Å; L394-F398 WeakPolarHBondContact O-CD2 3.5Å; L394-F398 PolarHBondContact O-N 3.33Å
395	L	86.6	Confident	83.4	Confident	1 Å²	1	38.3 Å²	38.3	1%	0.005	18%	0.182	C	C	.	.	H	α-helix	trans	-64.4	-38.8	-179.2	-92.2	63.2	0	0	0	111.7	L97 E179 F239 E393 T397 F398 T399 R412 V415	L97-L395 HydrophobicContact CD2-CD1 3.71Å; E179-L395 HydrophobicContact CG-CB 4.46Å; E179-L395 HydrophobicContact CG-CD2 4.2Å; E179-L395 WeakPolarHBondContact OE1-CB 3.43Å; F239-L395 HydrophobicContact CD2-CD1 4.05Å; F239-L395 HydrophobicContact CE2-CD1 3.34Å; F239-L395 HydrophobicContact CZ-CD1 4.09Å; E393-L395 PolarHBondContact O-N 3.47Å; L395-T397 VanDerWaalsContact C-N 3.26Å; L395-T397 PolarHBondContact O-N 3.47Å; L395-F398 WeakPolarHBondContact O-CB 3.43Å; L395-F398 PolarHBondContact O-N 2.72Å; L395-F398 VanDerWaalsContact O-N 3.12Å; L395-T399 PolarHBondContact O-N 3.03Å; L395-T399 VanDerWaalsContact O-N 3.15Å; L395-T399 PolarHBondContact O-OG1 3.44Å; L395-T399 VanDerWaalsContact O-OG1 3.13Å; L395-R412 HydrophobicContact CD2-CG 3.98Å; L395-V415 HydrophobicContact CD2-CB 4.22Å; L395-V415 HydrophobicContact CD2-CG1 4.28Å; L395-V415 HydrophobicContact CD2-CG2 4.26Å
396	H	85.8	Confident	83.3	Confident	62 Å²	62	42.6 Å²	42.6	29%	0.287	21%	0.209	S	C	.	.	H	α-helix	trans	-61.2	-37	174.5	-173	-90.7	0	0	0	111.7	E179 E391 E393 L394 F398 T399	E179-H396 PolarHBondContact OE1-N 3.44Å; E391-H396 IonicContact OE1-CE1 2.81Å; E391-H396 IonicContact OE1-ND1 3.87Å; E391-H396 IonicContact OE2-CE1 3.85Å; E391-H396 PolarHBondContact OE2-CE1 3.44Å; E391-H396 IonicContact OE2-CG 2.65Å; E391-H396 IonicContact OE2-ND1 3.47Å; E391-H396 PolarHBondContact OE2-ND1 3.04Å; E393-H396 HydrophobicContact CB-CB 4.15Å; E393-H396 HydrophobicContact CG-CB 4.18Å; E393-H396 PolarHBondContact O-N 2.81Å; L394-H396 VanDerWaalsContact C-N 3.32Å; L394-H396 PolarHBondContact O-N 3.44Å; H396-F398 VanDerWaalsContact C-N 3.34Å; H396-F398 PolarHBondContact O-N 3.26Å; H396-T399 VanDerWaalsContact O-CB 3.29Å; H396-T399 WeakPolarHBondContact O-CB 3.3Å; H396-T399 PolarHBondContact O-N 3.42Å; H396-T399 PolarHBondContact O-OG1 2.82Å
397	T	84.6	Confident	83.2	Confident	1 Å²	1	46.9 Å²	46.9	1%	0.006	23%	0.23	C	C	.	.	H	α-helix	trans	-62	-42	174.4	-48.3	0	0	0	0	111.3	F386 E391 E393 L394 L395 T399 K400	F386-T397 HydrophobicContact CB-CG2 4.08Å; F386-T397 HydrophobicContact CD1-CG2 3.65Å; F386-T397 HydrophobicContact CD2-CG2 3.55Å; F386-T397 HydrophobicContact CE1-CG2 3.84Å; F386-T397 HydrophobicContact CE2-CG2 3.75Å; F386-T397 HydrophobicContact CG-CG2 3.48Å; F386-T397 VanDerWaalsContact CG-CG2 3.48Å; F386-T397 HydrophobicContact CZ-CG2 3.89Å; E391-T397 WeakPolarHBondContact CB-OG1 3.41Å; E391-T397 PolarHBondContact N-OG1 3.35Å; E393-T397 PolarHBondContact O-N 2.92Å; E393-T397 PolarHBondContact O-OG1 3.09Å; L394-T397 WeakPolarHBondContact O-CB 3.48Å; L394-T397 PolarHBondContact O-N 3.01Å; L394-T397 VanDerWaalsContact O-N 3.14Å; L395-T397 VanDerWaalsContact C-N 3.26Å; L395-T397 PolarHBondContact O-N 3.47Å; T397-T399 VanDerWaalsContact C-N 3.31Å; T397-T399 PolarHBondContact O-N 3.24Å; T397-K400 PolarHBondContact O-N 3.5Å
398	F	84.8	Confident	83.1	Confident	4 Å²	4	46.1 Å²	46.1	2%	0.018	23%	0.227	C	C	.	.	H	α-helix	trans	-64.5	-31.5	176.3	-83.2	-79	0	0	0	113.2	I243 K246 L250 T385 F386 L394 L395 H396 K400 V401 Y402 L408	I243-F398 HydrophobicContact CG1-CE2 4.49Å; K246-F398 HydrophobicContact CB-CE1 4Å; K246-F398 HydrophobicContact CB-CZ 4.46Å; L250-F398 HydrophobicContact CD1-CE1 4.05Å; T385-F398 HydrophobicContact CG2-CE1 4.11Å; T385-F398 HydrophobicContact CG2-CZ 4.14Å; F386-F398 HydrophobicContact CE2-CD1 4.16Å; F386-F398 AromaticContact CE2-CD2 3.81Å; F386-F398 HydrophobicContact CE2-CD2 3.81Å; F386-F398 AromaticContact CE2-CE1 3.99Å; F386-F398 HydrophobicContact CE2-CE1 3.99Å; F386-F398 AromaticContact CE2-CE2 3.64Å; F386-F398 HydrophobicContact CE2-CE2 3.64Å; F386-F398 HydrophobicContact CE2-CG 4.06Å; F386-F398 AromaticContact CE2-CZ 3.72Å; F386-F398 HydrophobicContact CE2-CZ 3.72Å; F386-F398 HydrophobicContact CZ-CB 4.41Å; F386-F398 AromaticContact CZ-CD1 3.59Å; F386-F398 HydrophobicContact CZ-CD1 3.59Å; F386-F398 AromaticContact CZ-CD2 3.98Å; F386-F398 HydrophobicContact CZ-CD2 3.98Å; F386-F398 AromaticContact CZ-CE1 3.69Å; F386-F398 HydrophobicContact CZ-CE1 3.69Å; F386-F398 HydrophobicContact CZ-CE2 4.09Å; F386-F398 AromaticContact CZ-CG 3.72Å; F386-F398 HydrophobicContact CZ-CG 3.72Å; F386-F398 AromaticContact CZ-CZ 3.94Å; F386-F398 HydrophobicContact CZ-CZ 3.94Å; L394-F398 HydrophobicContact CD1-CD2 4.4Å; L394-F398 HydrophobicContact CD1-CE2 4.02Å; L394-F398 HydrophobicContact CD2-CE2 4.32Å; L394-F398 HydrophobicContact CG-CD2 4.17Å; L394-F398 HydrophobicContact CG-CE2 3.92Å; L394-F398 WeakPolarHBondContact O-CD2 3.5Å; L394-F398 PolarHBondContact O-N 3.33Å; L395-F398 WeakPolarHBondContact O-CB 3.43Å; L395-F398 PolarHBondContact O-N 2.72Å; L395-F398 VanDerWaalsContact O-N 3.12Å; H396-F398 VanDerWaalsContact C-N 3.34Å; H396-F398 PolarHBondContact O-N 3.26Å; F398-K400 PolarHBondContact O-N 3.15Å; F398-V401 PolarHBondContact O-N 3.46Å; F398-V401 VanDerWaalsContact O-N 3.09Å; F398-Y402 PolarHBondContact O-N 2.95Å; F398-L408 HydrophobicContact CB-CD1 3.82Å; F398-L408 HydrophobicContact CB-CD2 3.7Å; F398-L408 HydrophobicContact CB-CG 4.42Å; F398-L408 HydrophobicContact CD1-CD1 4.47Å; F398-L408 HydrophobicContact CG-CD1 4.07Å
399	T	80.8	Confident	83.4	Confident	15 Å²	15	43.9 Å²	43.9	9%	0.092	22%	0.215	C	C	.	.	H	α-helix	trans	-59	-34	176.7	-45.4	0	0	0	0	112.7	E182 L395 H396 T397 V401 R412	E182-T399 HydrophobicContact CG-CG2 4.25Å; L395-T399 PolarHBondContact O-N 3.03Å; L395-T399 VanDerWaalsContact O-N 3.15Å; L395-T399 PolarHBondContact O-OG1 3.44Å; L395-T399 VanDerWaalsContact O-OG1 3.13Å; H396-T399 VanDerWaalsContact O-CB 3.29Å; H396-T399 WeakPolarHBondContact O-CB 3.3Å; H396-T399 PolarHBondContact O-N 3.42Å; H396-T399 PolarHBondContact O-OG1 2.82Å; T397-T399 VanDerWaalsContact C-N 3.31Å; T397-T399 PolarHBondContact O-N 3.24Å; T399-V401 PolarHBondContact O-N 3.04Å; T399-R412 PolarHBondContact OG1-NH2 3.21Å
400	K	75.9	Confident	83.6	Confident	108 Å²	108	45.4 Å²	45.4	47%	0.47	23%	0.225	S	C	.	.	T	Hydrogen-bonded Turn	trans	-63.9	-25.9	178.6	-63.8	-171.4	-179.2	-179	0	112.6	E391 T397 F398	E391-K400 VanDerWaalsContact CD-CE 3.46Å; E391-K400 WeakPolarHBondContact OE1-CE 3.36Å; E391-K400 IonicContact OE1-NZ 3.72Å; E391-K400 PolarHBondContact OE1-NZ 3.35Å; E391-K400 WeakPolarHBondContact OE2-CE 3.47Å; E391-K400 IonicContact OE2-NZ 3.71Å; T397-K400 PolarHBondContact O-N 3.5Å; F398-K400 PolarHBondContact O-N 3.15Å
401	V	74.6	Confident	83.8	Confident	44 Å²	44	45.1 Å²	45.1	27%	0.267	22%	0.223	S	C	.	.	T	Hydrogen-bonded Turn	trans	-98.9	-49.6	-179.5	-171.3	0	0	0	0	111.5	L250 L254 F256 F386 F398 T399	L250-V401 HydrophobicContact CD2-CG1 3.88Å; L254-V401 HydrophobicContact CD1-CG2 4.26Å; F256-V401 HydrophobicContact CD1-CG2 3.72Å; F256-V401 HydrophobicContact CE1-CG2 3.46Å; F256-V401 VanDerWaalsContact CE1-CG2 3.46Å; F386-V401 HydrophobicContact CE1-CG2 3.89Å; F398-V401 PolarHBondContact O-N 3.46Å; F398-V401 VanDerWaalsContact O-N 3.09Å; T399-V401 PolarHBondContact O-N 3.04Å
402	Y	73.9	Confident	83.9	Confident	71 Å²	71	42.8 Å²	42.8	28%	0.278	21%	0.212	S	C	.	.			trans	-120.1	105.8	-175.4	-69.5	-68.8	0	0	0	110.7	L250 F398 D405	L250-Y402 HydrophobicContact CD1-CE2 4Å; L250-Y402 HydrophobicContact CD2-CE2 3.79Å; L250-Y402 HydrophobicContact CG-CE2 4.02Å; F398-Y402 PolarHBondContact O-N 2.95Å; Y402-D405 HydrophobicContact CD1-CB 4.1Å; Y402-D405 HydrophobicContact CG-CB 4.06Å
403	K	67.4	Low	84.2	Confident	130 Å²	130	44.5 Å²	44.5	57%	0.565	22%	0.218	S	C	*	.	S	Bend	trans	-80.3	-40.9	175.3	-69.9	-171.7	175.7	-175.4	0	113.1
404	F	70.3	Confident	84.4	Confident	86 Å²	86	44.7 Å²	44.7	38%	0.377	22%	0.222	S	C	.	.	S	Bend	trans	-122.4	23.2	-170	-57.1	-70.3	0	0	0	114.2	A186 E191 T406	A186-F404 HydrophobicContact CB-CD1 4.47Å; E191-F404 HydrophobicContact CG-CE2 4.21Å; E191-F404 HydrophobicContact CG-CZ 4.15Å; F404-T406 PolarHBondContact O-N 3.26Å
405	D	83	Confident	84.6	Confident	38 Å²	38	44.8 Å²	44.8	20%	0.203	22%	0.222	C	C	.	.			trans	-74.5	120.5	179.5	-173.5	-75.7	0	0	0	111.5	K246 Y402 M407 L408 L409	K246-D405 WeakPolarHBondContact CE-OD1 3.45Å; K246-D405 IonicContact NZ-OD1 2.94Å; K246-D405 PolarHBondContact NZ-OD1 3.36Å; K246-D405 IonicContact NZ-OD2 2.61Å; K246-D405 PolarHBondContact NZ-OD2 3.39Å; Y402-D405 HydrophobicContact CD1-CB 4.1Å; Y402-D405 HydrophobicContact CG-CB 4.06Å; D405-M407 VanDerWaalsContact C-N 3.3Å; D405-M407 PolarHBondContact O-N 3.31Å; D405-M407 WeakPolarHBondContact OD1-CB 3.48Å; D405-M407 PolarHBondContact OD1-N 2.99Å; D405-L408 HydrophobicContact CB-CB 4.12Å; D405-L408 PolarHBondContact O-N 3.09Å; D405-L408 PolarHBondContact OD1-N 2.75Å; D405-L408 VanDerWaalsContact OD1-N 3.15Å; D405-L409 PolarHBondContact O-N 3.35Å
406	T	86.6	Confident	84.9	Confident	96 Å²	96	45.3 Å²	45.3	59%	0.589	23%	0.225	S	C	*	.	H	α-helix	trans	-59.9	-36.7	-176.2	-48.4	0	0	0	0	113	F404 L409 L410	F404-T406 PolarHBondContact O-N 3.26Å; T406-L409 PolarHBondContact O-N 3.11Å; T406-L410 WeakPolarHBondContact O-CG 3.5Å; T406-L410 PolarHBondContact O-N 3.44Å
407	M	87.1	Confident	85.2	Confident	90 Å²	90	45.1 Å²	45.1	44%	0.443	23%	0.228	S	C	.	.	H	α-helix	trans	-68.8	-41.5	179.4	-67.6	-68.1	148.2	0	0	110.8	V242 D405 L410 V411	V242-M407 HydrophobicContact CG1-CB 4.47Å; D405-M407 VanDerWaalsContact C-N 3.3Å; D405-M407 PolarHBondContact O-N 3.31Å; D405-M407 WeakPolarHBondContact OD1-CB 3.48Å; D405-M407 PolarHBondContact OD1-N 2.99Å; M407-L410 PolarHBondContact O-N 2.67Å; M407-V411 WeakPolarHBondContact O-CG2 3.45Å; M407-V411 PolarHBondContact O-N 3.44Å; M407-V411 VanDerWaalsContact O-N 3.08Å
408	L	86.9	Confident	85.6	Confident	6 Å²	6	45.1 Å²	45.1	3%	0.031	23%	0.228	C	C	.	.	H	α-helix	trans	-66.4	-38.5	175.4	-172.1	65.9	0	0	0	111.5	F398 D405 L410 V411 R412	F398-L408 HydrophobicContact CB-CD1 3.82Å; F398-L408 HydrophobicContact CB-CD2 3.7Å; F398-L408 HydrophobicContact CB-CG 4.42Å; F398-L408 HydrophobicContact CD1-CD1 4.47Å; F398-L408 HydrophobicContact CG-CD1 4.07Å; D405-L408 HydrophobicContact CB-CB 4.12Å; D405-L408 PolarHBondContact O-N 3.09Å; D405-L408 PolarHBondContact OD1-N 2.75Å; D405-L408 VanDerWaalsContact OD1-N 3.15Å; L408-L410 PolarHBondContact O-N 3Å; L408-V411 WeakPolarHBondContact O-CB 3.26Å; L408-V411 PolarHBondContact O-N 3.13Å; L408-R412 WeakPolarHBondContact O-CG 3.46Å; L408-R412 PolarHBondContact O-N 2.98Å
409	L	90.4	Very high	86	Confident	27 Å²	27	45 Å²	45	14%	0.141	23%	0.227	C	C	.	.	H	α-helix	trans	-59.7	-45	174.2	-179.9	60.4	0	0	0	112	V183 A186 F187 D405 T406 V411 R412 L413	V183-L409 HydrophobicContact CB-CD1 4.24Å; V183-L409 HydrophobicContact CG1-CD1 3.99Å; V183-L409 HydrophobicContact CG2-CD1 4.08Å; A186-L409 HydrophobicContact CB-CD1 3.77Å; A186-L409 HydrophobicContact CB-CD2 4.18Å; A186-L409 HydrophobicContact CB-CG 4.5Å; F187-L409 HydrophobicContact CD2-CD1 4.49Å; F187-L409 HydrophobicContact CE1-CD2 4.44Å; F187-L409 HydrophobicContact CE2-CD1 4.24Å; F187-L409 HydrophobicContact CE2-CD2 4.39Å; F187-L409 HydrophobicContact CZ-CD2 4.28Å; D405-L409 PolarHBondContact O-N 3.35Å; T406-L409 PolarHBondContact O-N 3.11Å; L409-V411 VanDerWaalsContact C-N 3.31Å; L409-V411 PolarHBondContact O-N 2.99Å; L409-R412 PolarHBondContact O-N 3.23Å; L409-L413 HydrophobicContact CG-CD1 4.38Å; L409-L413 WeakPolarHBondContact O-CG 3.47Å; L409-L413 PolarHBondContact O-N 2.9Å
410	L	91.9	Very high	86.5	Confident	83 Å²	83	45.1 Å²	45.1	44%	0.435	23%	0.228	S	C	.	.	H	α-helix	trans	-61.3	-40	175.4	-71.8	176.3	0	0	0	111.9	F238 T406 M407 L408 L413 A414	F238-L410 HydrophobicContact CE1-CB 4.06Å; F238-L410 HydrophobicContact CZ-CB 4.07Å; T406-L410 WeakPolarHBondContact O-CG 3.5Å; T406-L410 PolarHBondContact O-N 3.44Å; M407-L410 PolarHBondContact O-N 2.67Å; L408-L410 PolarHBondContact O-N 3Å; L410-L413 PolarHBondContact O-N 2.77Å; L410-A414 WeakPolarHBondContact O-CB 3.47Å; L410-A414 PolarHBondContact O-N 3.42Å
411	V	92.4	Very high	87.1	Confident	3 Å²	3	42.2 Å²	42.2	2%	0.018	22%	0.217	C	C	.	.	H	α-helix	trans	-63.4	-45.9	175	165.3	0	0	0	0	111.7	F238 F239 V242 M407 L408 L409 L413 A414 V415	F238-V411 HydrophobicContact CD1-CG2 4.14Å; F238-V411 HydrophobicContact CE1-CB 4.45Å; F238-V411 HydrophobicContact CE1-CG2 3.65Å; F238-V411 HydrophobicContact CZ-CG2 4.2Å; F239-V411 HydrophobicContact CB-CG1 4.19Å; F239-V411 HydrophobicContact CD2-CG1 3.56Å; F239-V411 HydrophobicContact CE2-CG1 4.46Å; F239-V411 HydrophobicContact CG-CG1 4.36Å; V242-V411 HydrophobicContact CB-CG2 3.5Å; V242-V411 HydrophobicContact CG1-CG2 3.57Å; V242-V411 HydrophobicContact CG2-CG2 3.58Å; M407-V411 WeakPolarHBondContact O-CG2 3.45Å; M407-V411 PolarHBondContact O-N 3.44Å; M407-V411 VanDerWaalsContact O-N 3.08Å; L408-V411 WeakPolarHBondContact O-CB 3.26Å; L408-V411 PolarHBondContact O-N 3.13Å; L409-V411 VanDerWaalsContact C-N 3.31Å; L409-V411 PolarHBondContact O-N 2.99Å; V411-L413 VanDerWaalsContact C-N 3.32Å; V411-L413 PolarHBondContact O-N 3.45Å; V411-A414 WeakPolarHBondContact O-CB 3.46Å; V411-A414 PolarHBondContact O-N 3.39Å; V411-A414 VanDerWaalsContact O-N 3.16Å; V411-V415 HydrophobicContact CG1-CG2 4.34Å; V411-V415 WeakPolarHBondContact O-CG2 3.19Å; V411-V415 PolarHBondContact O-N 3.44Å
412	R	92.8	Very high	87.9	Confident	3 Å²	3	40.3 Å²	40.3	1%	0.011	21%	0.206	C	C	.	.	H	α-helix	trans	-58	-45.9	176.7	-71.6	-170.5	176.2	136.9	15.4	111.4	E179 V183 L395 T399 L408 L409 A414 V415 L416	E179-R412 WeakPolarHBondContact OE2-CD 3.46Å; E179-R412 WeakPolarHBondContact OE2-CG 3.38Å; E179-R412 IonicContact OE2-NE 3.05Å; E179-R412 PolarHBondContact OE2-NE 2.88Å; V183-R412 HydrophobicContact CG2-CB 3.53Å; V183-R412 HydrophobicContact CG2-CG 4.39Å; L395-R412 HydrophobicContact CD2-CG 3.98Å; T399-R412 PolarHBondContact OG1-NH2 3.21Å; L408-R412 WeakPolarHBondContact O-CG 3.46Å; L408-R412 PolarHBondContact O-N 2.98Å; L409-R412 PolarHBondContact O-N 3.23Å; R412-A414 VanDerWaalsContact C-N 3.34Å; R412-A414 PolarHBondContact O-N 2.99Å; R412-V415 PolarHBondContact O-N 3.18Å; R412-L416 VanDerWaalsContact O-CB 3.25Å; R412-L416 WeakPolarHBondContact O-CB 3.32Å; R412-L416 VanDerWaalsContact O-CG 3.29Å; R412-L416 WeakPolarHBondContact O-CG 3.35Å; R412-L416 PolarHBondContact O-N 3.38Å
413	L	93.4	Very high	88.7	Confident	57 Å²	57	37 Å²	37	30%	0.298	19%	0.193	S	C	.	.	H	α-helix	trans	-60.8	-42.6	175.8	-75.1	168.2	0	0	0	112.1	V183 F187 L409 L410 V411 T417	V183-L413 HydrophobicContact CG1-CD2 3.61Å; V183-L413 HydrophobicContact CG1-CG 4.11Å; F187-L413 HydrophobicContact CE2-CD1 3.89Å; F187-L413 HydrophobicContact CE2-CD2 4.18Å; F187-L413 HydrophobicContact CE2-CG 4.44Å; F187-L413 HydrophobicContact CZ-CD1 3.77Å; L409-L413 HydrophobicContact CG-CD1 4.38Å; L409-L413 WeakPolarHBondContact O-CG 3.47Å; L409-L413 PolarHBondContact O-N 2.9Å; L410-L413 PolarHBondContact O-N 2.77Å; V411-L413 VanDerWaalsContact C-N 3.32Å; V411-L413 PolarHBondContact O-N 3.45Å; L413-T417 VanDerWaalsContact O-CB 3.32Å; L413-T417 WeakPolarHBondContact O-CB 3.27Å; L413-T417 PolarHBondContact O-N 2.9Å; L413-T417 PolarHBondContact O-OG1 3.47Å
414	A	93.3	Very high	89.8	Confident	14 Å²	14	31.2 Å²	31.2	12%	0.116	17%	0.169	C	C	.	.	H	α-helix	trans	-63.3	-47.5	177.8	0	0	0	0	0	111.6	C235 F238 L410 V411 R412 T417 A418	C235-A414 HydrophobicContact CB-CB 3.92Å; F238-A414 HydrophobicContact CD1-CB 4.02Å; F238-A414 HydrophobicContact CE1-CB 4.47Å; L410-A414 WeakPolarHBondContact O-CB 3.47Å; L410-A414 PolarHBondContact O-N 3.42Å; V411-A414 WeakPolarHBondContact O-CB 3.46Å; V411-A414 PolarHBondContact O-N 3.39Å; V411-A414 VanDerWaalsContact O-N 3.16Å; R412-A414 VanDerWaalsContact C-N 3.34Å; R412-A414 PolarHBondContact O-N 2.99Å; A414-T417 PolarHBondContact O-N 3.42Å; A414-A418 VanDerWaalsContact O-CB 3.31Å; A414-A418 WeakPolarHBondContact O-CB 3.22Å; A414-A418 PolarHBondContact O-N 2.75Å
415	V	92.9	Very high	90.5	Very high	1 Å²	1	28.1 Å²	28.1	1%	0.006	16%	0.156	C	C	.	.	H	α-helix	trans	-63.6	-48.1	177.1	172.6	0	0	0	0	110.7	L97 I175 M236 F239 L395 V411 R412 T417 A418 V419	L97-V415 HydrophobicContact CD1-CG1 4.24Å; I175-V415 HydrophobicContact CG2-CG1 4.19Å; M236-V415 HydrophobicContact CE-CG1 4.44Å; M236-V415 HydrophobicContact SD-CG2 4.21Å; F239-V415 HydrophobicContact CB-CG2 4.23Å; F239-V415 HydrophobicContact CD2-CG2 4.25Å; F239-V415 HydrophobicContact CG-CG2 4.29Å; L395-V415 HydrophobicContact CD2-CB 4.22Å; L395-V415 HydrophobicContact CD2-CG1 4.28Å; L395-V415 HydrophobicContact CD2-CG2 4.26Å; V411-V415 HydrophobicContact CG1-CG2 4.34Å; V411-V415 WeakPolarHBondContact O-CG2 3.19Å; V411-V415 PolarHBondContact O-N 3.44Å; R412-V415 PolarHBondContact O-N 3.18Å; V415-T417 VanDerWaalsContact C-N 3.32Å; V415-T417 PolarHBondContact O-N 3.39Å; V415-A418 PolarHBondContact O-N 2.97Å; V415-V419 HydrophobicContact CG1-CG1 4.35Å; V415-V419 WeakPolarHBondContact O-CG1 3.42Å; V415-V419 WeakPolarHBondContact O-CG2 3.44Å; V415-V419 PolarHBondContact O-N 2.89Å
416	L	94.2	Very high	90.7	Very high	13 Å²	13	27 Å²	27	7%	0.068	15%	0.151	C	C	.	.	H	α-helix	trans	-57.6	-43.6	176.9	-80.2	171.6	0	0	0	112.2	V176 E179 L180 V183 R412 V419 T420	V176-L416 HydrophobicContact CB-CD2 4.4Å; V176-L416 HydrophobicContact CG2-CD2 4.11Å; E179-L416 HydrophobicContact CB-CD1 4.27Å; E179-L416 HydrophobicContact CB-CD2 3.97Å; E179-L416 HydrophobicContact CB-CG 4.14Å; L180-L416 HydrophobicContact CB-CD1 4.34Å; L180-L416 HydrophobicContact CB-CD2 4.41Å; L180-L416 HydrophobicContact CD1-CD1 4.27Å; V183-L416 HydrophobicContact CB-CD1 4.34Å; V183-L416 HydrophobicContact CG2-CD1 3.67Å; R412-L416 VanDerWaalsContact O-CB 3.25Å; R412-L416 WeakPolarHBondContact O-CB 3.32Å; R412-L416 VanDerWaalsContact O-CG 3.29Å; R412-L416 WeakPolarHBondContact O-CG 3.35Å; R412-L416 PolarHBondContact O-N 3.38Å; L416-V419 WeakPolarHBondContact O-CG2 3.43Å; L416-T420 WeakPolarHBondContact O-CB 3.18Å; L416-T420 PolarHBondContact O-N 3.04Å; L416-T420 PolarHBondContact O-OG1 3.32Å
417	T	92.1	Very high	90.8	Very high	58 Å²	58	22.4 Å²	22.4	36%	0.356	12%	0.123	S	C	.	.	H	α-helix	trans	-65.6	-46.3	177.9	-53.8	0	0	0	0	110.5	F231 L413 A414 V415 T420 L421	F231-T417 HydrophobicContact CE1-CG2 3.76Å; F231-T417 HydrophobicContact CZ-CG2 4.46Å; L413-T417 VanDerWaalsContact O-CB 3.32Å; L413-T417 WeakPolarHBondContact O-CB 3.27Å; L413-T417 PolarHBondContact O-N 2.9Å; L413-T417 PolarHBondContact O-OG1 3.47Å; A414-T417 PolarHBondContact O-N 3.42Å; V415-T417 VanDerWaalsContact C-N 3.32Å; V415-T417 PolarHBondContact O-N 3.39Å; T417-T420 PolarHBondContact O-N 3.14Å; T417-L421 HydrophobicContact CG2-CD1 4.03Å; T417-L421 HydrophobicContact CG2-CG 4.43Å; T417-L421 WeakPolarHBondContact O-CB 3.43Å; T417-L421 VanDerWaalsContact O-CG 3.29Å; T417-L421 WeakPolarHBondContact O-CG 3.36Å; T417-L421 PolarHBondContact O-N 3.46Å
418	A	92.3	Very high	90.6	Very high	0 Å²	0	22.1 Å²	22.1	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-59.6	-48.7	179	0	0	0	0	0	112.8	C235 M236 A414 V415 L421 T422	C235-A418 HydrophobicContact CB-CB 4.03Å; M236-A418 HydrophobicContact CE-CB 3.91Å; A414-A418 VanDerWaalsContact O-CB 3.31Å; A414-A418 WeakPolarHBondContact O-CB 3.22Å; A414-A418 PolarHBondContact O-N 2.75Å; V415-A418 PolarHBondContact O-N 2.97Å; A418-L421 PolarHBondContact O-N 3.38Å; A418-T422 WeakPolarHBondContact O-CB 3.18Å; A418-T422 PolarHBondContact O-N 3.44Å; A418-T422 VanDerWaalsContact O-N 3.13Å; A418-T422 PolarHBondContact O-OG1 3.29Å
419	V	92.8	Very high	90.3	Very high	1 Å²	1	22.8 Å²	22.8	1%	0.006	12%	0.124	C	C	.	.	H	α-helix	trans	-68.1	-38.6	179	-58.4	0	0	0	0	111.8	Y172 I175 V176 M236 V415 L416 L421 T422 V423	Y172-V419 HydrophobicContact CD1-CB 3.69Å; Y172-V419 HydrophobicContact CD1-CG1 3.7Å; Y172-V419 HydrophobicContact CE1-CG1 4.25Å; Y172-V419 HydrophobicContact CG-CB 4.14Å; I175-V419 HydrophobicContact CD1-CG1 4.05Å; I175-V419 HydrophobicContact CG2-CG2 4.29Å; V176-V419 HydrophobicContact CG2-CG2 4.09Å; M236-V419 HydrophobicContact CE-CG1 4.27Å; V415-V419 HydrophobicContact CG1-CG1 4.35Å; V415-V419 WeakPolarHBondContact O-CG1 3.42Å; V415-V419 WeakPolarHBondContact O-CG2 3.44Å; V415-V419 PolarHBondContact O-N 2.89Å; L416-V419 WeakPolarHBondContact O-CG2 3.43Å; V419-L421 VanDerWaalsContact C-N 3.34Å; V419-L421 PolarHBondContact O-N 2.65Å; V419-T422 PolarHBondContact O-N 3.39Å; V419-T422 VanDerWaalsContact O-N 3.09Å; V419-V423 PolarHBondContact O-N 2.93Å; V419-V423 VanDerWaalsContact O-N 3.12Å
420	T	92.4	Very high	90	Very high	18 Å²	18	21.6 Å²	21.6	11%	0.11	12%	0.117	C	C	.	.	H	α-helix	trans	-63.4	-40.3	177.7	-59	0	0	0	0	111.7	V208 I212 I213 L416 T417 T422 P424	V208-T420 HydrophobicContact CG1-CG2 4.25Å; I212-T420 HydrophobicContact CG2-CG2 3.82Å; I213-T420 HydrophobicContact CD1-CG2 4.45Å; I213-T420 HydrophobicContact CG1-CG2 3.96Å; L416-T420 WeakPolarHBondContact O-CB 3.18Å; L416-T420 PolarHBondContact O-N 3.04Å; L416-T420 PolarHBondContact O-OG1 3.32Å; T417-T420 PolarHBondContact O-N 3.14Å; T420-T422 VanDerWaalsContact C-N 3.26Å; T420-T422 PolarHBondContact O-N 2.87Å; T420-P424 WeakPolarHBondContact O-CD 3.37Å
421	L	89.1	Confident	89.7	Confident	47 Å²	47	18.2 Å²	18.2	25%	0.246	10%	0.099	C	C	.	.	H	α-helix	trans	-70.9	-22	175.4	-69.3	176.1	0	0	0	113.1	L216 F231 T417 A418 V419	L216-L421 HydrophobicContact CD1-CD2 4.34Å; F231-L421 HydrophobicContact CD1-CD1 3.77Å; F231-L421 HydrophobicContact CE1-CD1 4.08Å; T417-L421 HydrophobicContact CG2-CD1 4.03Å; T417-L421 HydrophobicContact CG2-CG 4.43Å; T417-L421 WeakPolarHBondContact O-CB 3.43Å; T417-L421 VanDerWaalsContact O-CG 3.29Å; T417-L421 WeakPolarHBondContact O-CG 3.36Å; T417-L421 PolarHBondContact O-N 3.46Å; A418-L421 PolarHBondContact O-N 3.38Å; V419-L421 VanDerWaalsContact C-N 3.34Å; V419-L421 PolarHBondContact O-N 2.65Å
422	T	89.9	Confident	89.1	Confident	5 Å²	5	20.7 Å²	20.7	3%	0.031	12%	0.116	C	C	.	.	H	α-helix	trans	-85.7	-26.8	-178.8	-58.1	0	0	0	0	112.3	N89 Y172 A418 V419 T420 I425 V426	N89-T422 PolarHBondContact ND2-OG1 2.9Å; Y172-T422 HydrophobicContact CD2-CG2 4.47Å; Y172-T422 HydrophobicContact CE1-CG2 4.41Å; Y172-T422 HydrophobicContact CE2-CG2 3.67Å; A418-T422 WeakPolarHBondContact O-CB 3.18Å; A418-T422 PolarHBondContact O-N 3.44Å; A418-T422 VanDerWaalsContact O-N 3.13Å; A418-T422 PolarHBondContact O-OG1 3.29Å; V419-T422 PolarHBondContact O-N 3.39Å; V419-T422 VanDerWaalsContact O-N 3.09Å; T420-T422 VanDerWaalsContact C-N 3.26Å; T420-T422 PolarHBondContact O-N 2.87Å; T422-I425 VanDerWaalsContact O-CB 3.28Å; T422-I425 WeakPolarHBondContact O-CB 3.37Å; T422-I425 PolarHBondContact O-N 2.81Å; T422-I425 VanDerWaalsContact O-N 3.12Å; T422-V426 HydrophobicContact CG2-CG2 4.3Å; T422-V426 PolarHBondContact O-N 3.28Å; T422-V426 VanDerWaalsContact O-N 3.15Å
423	V	91.9	Very high	88.5	Confident	0 Å²	0	21 Å²	21	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-57.6	-47.5	178	173	0	0	0	0	113.4	M169 Y172 I213 V419 I425 V426 L427	M169-V423 HydrophobicContact CG-CG1 3.82Å; M169-V423 HydrophobicContact SD-CG1 4.09Å; Y172-V423 HydrophobicContact CD2-CG2 3.84Å; Y172-V423 HydrophobicContact CG-CG2 4.07Å; I213-V423 HydrophobicContact CD1-CB 4.23Å; I213-V423 HydrophobicContact CD1-CG1 4.19Å; I213-V423 HydrophobicContact CD1-CG2 4.33Å; I213-V423 HydrophobicContact CG2-CB 4.06Å; I213-V423 HydrophobicContact CG2-CG1 3.4Å; I213-V423 VanDerWaalsContact CG2-CG1 3.4Å; V419-V423 PolarHBondContact O-N 2.93Å; V419-V423 VanDerWaalsContact O-N 3.12Å; V423-I425 PolarHBondContact O-N 3.18Å; V423-V426 PolarHBondContact O-N 3.06Å; V423-L427 WeakPolarHBondContact O-CB 3.15Å; V423-L427 PolarHBondContact O-N 3.4Å
424	P	88.9	Confident	88.1	Confident	9 Å²	9	20.1 Å²	20.1	6%	0.058	11%	0.114	C	C	.	.	H	α-helix	trans	-58.5	-34	175.9	-26.6	35.5	0	0	0	113.6	I213 L216 T420 L427 F428	I213-P424 HydrophobicContact CG2-CG 4.41Å; L216-P424 HydrophobicContact CB-CB 4.25Å; L216-P424 HydrophobicContact CB-CG 3.69Å; L216-P424 HydrophobicContact CD1-CG 4.38Å; T420-P424 WeakPolarHBondContact O-CD 3.37Å; P424-L427 PolarHBondContact O-N 2.99Å; P424-F428 PolarHBondContact O-N 3.36Å
425	I	85.2	Confident	87.6	Confident	21 Å²	21	21.4 Å²	21.4	11%	0.108	12%	0.121	C	C	.	.	H	α-helix	trans	-63.2	-50.1	177.8	-53.7	-176.5	0	0	0	109.6	L225 T422 V423 L427 F428 P429	L225-I425 HydrophobicContact CD1-CD1 3.92Å; L225-I425 HydrophobicContact CD1-CG1 3.59Å; L225-I425 HydrophobicContact CD2-CG1 4.32Å; L225-I425 HydrophobicContact CD2-CG2 3.91Å; L225-I425 HydrophobicContact CG-CD1 3.89Å; L225-I425 HydrophobicContact CG-CG1 3.92Å; L225-I425 HydrophobicContact CG-CG2 4.32Å; T422-I425 VanDerWaalsContact O-CB 3.28Å; T422-I425 WeakPolarHBondContact O-CB 3.37Å; T422-I425 PolarHBondContact O-N 2.81Å; T422-I425 VanDerWaalsContact O-N 3.12Å; V423-I425 PolarHBondContact O-N 3.18Å; I425-L427 VanDerWaalsContact C-N 3.31Å; I425-L427 PolarHBondContact O-N 3.17Å; I425-F428 WeakPolarHBondContact O-CB 3.39Å; I425-F428 PolarHBondContact O-N 3.46Å; I425-P429 WeakPolarHBondContact O-CD 3.5Å
426	V	87.7	Confident	86.8	Confident	15 Å²	15	25.1 Å²	25.1	9%	0.091	14%	0.143	C	C	.	.	H	α-helix	trans	-71.7	-26	-179.3	177.5	0	0	0	0	112.4	N165 A168 M169 Y172 T422 V423 P429	N165-V426 HydrophobicContact CB-CG1 3.7Å; N165-V426 VanDerWaalsContact O-CG1 3.23Å; N165-V426 WeakPolarHBondContact O-CG1 3.3Å; A168-V426 HydrophobicContact CB-CG1 4.26Å; M169-V426 HydrophobicContact CB-CG1 4.4Å; M169-V426 HydrophobicContact CE-CG1 4.48Å; Y172-V426 HydrophobicContact CE2-CG2 3.99Å; T422-V426 HydrophobicContact CG2-CG2 4.3Å; T422-V426 PolarHBondContact O-N 3.28Å; T422-V426 VanDerWaalsContact O-N 3.15Å; V423-V426 PolarHBondContact O-N 3.06Å; V426-P429 VanDerWaalsContact O-CD 3.31Å; V426-P429 WeakPolarHBondContact O-CD 3.26Å; V426-P429 WeakPolarHBondContact O-CG 3.33Å
427	L	88.7	Confident	86.1	Confident	0 Å²	0	27.7 Å²	27.7	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-68.8	-35.4	174.9	-167.6	150.9	0	0	0	112.1	M169 V423 P424 I425 I430 R431 A453 I456	M169-L427 HydrophobicContact CE-CB 3.63Å; M169-L427 HydrophobicContact CE-CD1 4.23Å; M169-L427 HydrophobicContact CE-CG 4.02Å; M169-L427 HydrophobicContact SD-CD1 4.45Å; V423-L427 WeakPolarHBondContact O-CB 3.15Å; V423-L427 PolarHBondContact O-N 3.4Å; P424-L427 PolarHBondContact O-N 2.99Å; I425-L427 VanDerWaalsContact C-N 3.31Å; I425-L427 PolarHBondContact O-N 3.17Å; L427-I430 PolarHBondContact O-N 3.28Å; L427-R431 HydrophobicContact CD2-CB 4.18Å; L427-R431 PolarHBondContact O-N 3.43Å; L427-A453 HydrophobicContact CD2-CB 4.04Å; L427-I456 HydrophobicContact CD1-CG2 4.44Å; L427-I456 HydrophobicContact CG-CG2 4.39Å
428	F	83	Confident	85.6	Confident	84 Å²	84	30.5 Å²	30.5	37%	0.368	17%	0.169	S	C	.	.	H	α-helix	trans	-53.1	-53.9	-177.5	-176.8	-90.1	0	0	0	114.1	L222 P424 I425 I430 R431 S432	L222-F428 HydrophobicContact CD1-CB 3.86Å; L222-F428 HydrophobicContact CD1-CD2 3.54Å; L222-F428 HydrophobicContact CD1-CE2 4.26Å; L222-F428 HydrophobicContact CD1-CG 3.76Å; L222-F428 HydrophobicContact CG-CD2 4.48Å; P424-F428 PolarHBondContact O-N 3.36Å; I425-F428 WeakPolarHBondContact O-CB 3.39Å; I425-F428 PolarHBondContact O-N 3.46Å; F428-I430 PolarHBondContact O-N 3.05Å; F428-R431 PolarHBondContact O-N 3.34Å; F428-S432 WeakPolarHBondContact O-CB 3.49Å; F428-S432 PolarHBondContact O-N 3.2Å
429	P	79.9	Confident	85.1	Confident	20 Å²	20	33.1 Å²	33.1	13%	0.13	18%	0.181	C	C	.	.	H	α-helix	trans	-63.1	-40.6	178.5	23.8	-33.7	0	0	0	112	I425 V426 R431 S432 S433	I425-P429 WeakPolarHBondContact O-CD 3.5Å; V426-P429 VanDerWaalsContact O-CD 3.31Å; V426-P429 WeakPolarHBondContact O-CD 3.26Å; V426-P429 WeakPolarHBondContact O-CG 3.33Å; P429-R431 VanDerWaalsContact C-N 3.33Å; P429-R431 PolarHBondContact O-N 2.69Å; P429-S432 PolarHBondContact O-N 2.62Å; P429-S433 WeakPolarHBondContact O-CB 3.44Å; P429-S433 PolarHBondContact O-N 3Å; P429-S433 PolarHBondContact O-OG 3.5Å; P429-S433 VanDerWaalsContact O-OG 3.1Å
430	I	85.8	Confident	84.2	Confident	1 Å²	1	41.5 Å²	41.5	1%	0.005	22%	0.217	C	C	.	.	H	α-helix	trans	-57.3	-49.1	176.8	-55.6	173.5	0	0	0	110.4	I162 N165 I166 M169 L427 F428 S432 S433 I434 I456	I162-I430 HydrophobicContact CG1-CG2 4.44Å; N165-I430 HydrophobicContact CB-CD1 3.57Å; N165-I430 HydrophobicContact CB-CG1 3.37Å; I166-I430 HydrophobicContact CG1-CD1 4.14Å; M169-I430 HydrophobicContact CE-CD1 3.56Å; L427-I430 PolarHBondContact O-N 3.28Å; F428-I430 PolarHBondContact O-N 3.05Å; I430-S432 VanDerWaalsContact C-N 3.34Å; I430-S432 PolarHBondContact O-N 3.28Å; I430-S433 PolarHBondContact O-N 3.44Å; I430-I434 HydrophobicContact CG2-CD1 3.81Å; I430-I434 HydrophobicContact CG2-CG1 4.46Å; I430-I434 WeakPolarHBondContact O-CB 3.38Å; I430-I434 WeakPolarHBondContact O-CG1 3.25Å; I430-I434 PolarHBondContact O-N 2.84Å; I430-I456 HydrophobicContact CB-CD1 4.22Å; I430-I456 HydrophobicContact CD1-CG2 4.16Å; I430-I456 HydrophobicContact CG2-CD1 3.66Å; I430-I456 HydrophobicContact CG2-CG1 4.07Å; I430-I456 HydrophobicContact CG2-CG2 4.23Å
431	R	85.8	Confident	83.2	Confident	13 Å²	13	44.6 Å²	44.6	5%	0.049	25%	0.252	C	S	.	.	H	α-helix	trans	-62.5	-43	179.3	-179.7	-175.7	67.5	-162.3	0.6	111.4	S217 L427 F428 P429 I434 T435 H449 I452 I456	S217-R431 PolarHBondContact O-NH1 3.3Å; L427-R431 HydrophobicContact CD2-CB 4.18Å; L427-R431 PolarHBondContact O-N 3.43Å; F428-R431 PolarHBondContact O-N 3.34Å; P429-R431 VanDerWaalsContact C-N 3.33Å; P429-R431 PolarHBondContact O-N 2.69Å; R431-I434 PolarHBondContact O-N 3.37Å; R431-T435 VanDerWaalsContact O-CB 3.27Å; R431-T435 WeakPolarHBondContact O-CB 3.29Å; R431-T435 PolarHBondContact O-N 2.88Å; R431-T435 PolarHBondContact O-OG1 2.91Å; R431-H449 PolarHBondContact NE-CE1 3.37Å; R431-H449 PolarHBondContact NH1-CE1 3.41Å; R431-H449 PolarHBondContact NH1-NE2 3.22Å; R431-H449 PolarHBondContact NH2-CE1 2.67Å; R431-I452 HydrophobicContact CB-CG2 4.38Å; R431-I452 HydrophobicContact CG-CG2 3.9Å; R431-I456 HydrophobicContact CB-CD1 4.27Å
432	S	78.6	Confident	82.6	Confident	55 Å²	55	50.8 Å²	50.8	39%	0.385	27%	0.272	S	S	.	.	H	α-helix	trans	-61.4	-47.7	178.5	-170.2	0	0	0	0	111.3	F428 P429 I430 T435 T436	F428-S432 WeakPolarHBondContact O-CB 3.49Å; F428-S432 PolarHBondContact O-N 3.2Å; P429-S432 PolarHBondContact O-N 2.62Å; I430-S432 VanDerWaalsContact C-N 3.34Å; I430-S432 PolarHBondContact O-N 3.28Å; S432-T435 PolarHBondContact O-N 3.45Å; S432-T436 WeakPolarHBondContact O-CB 3.1Å; S432-T436 PolarHBondContact O-N 2.78Å; S432-T436 PolarHBondContact O-OG1 3.2Å
433	S	80.4	Confident	82.2	Confident	9 Å²	9	57.6 Å²	57.6	6%	0.063	31%	0.309	C	S	.	.	H	α-helix	trans	-61.7	-47.6	177.7	-60.5	0	0	0	0	111.1	E142 F158 P429 I430 T435 T436 L437	E142-S433 PolarHBondContact OE1-OG 3.32Å; F158-S433 WeakPolarHBondContact CE2-O 3.45Å; P429-S433 WeakPolarHBondContact O-CB 3.44Å; P429-S433 PolarHBondContact O-N 3Å; P429-S433 PolarHBondContact O-OG 3.5Å; P429-S433 VanDerWaalsContact O-OG 3.1Å; I430-S433 PolarHBondContact O-N 3.44Å; S433-T435 PolarHBondContact O-N 3.37Å; S433-T436 PolarHBondContact O-N 3.4Å; S433-L437 WeakPolarHBondContact O-CB 3.21Å; S433-L437 PolarHBondContact O-N 3.34Å
434	I	84	Confident	81.7	Confident	38 Å²	38	62.8 Å²	62.8	20%	0.195	33%	0.331	C	S	.	.	H	α-helix	trans	-61.5	-43.7	178.1	-70.7	174.2	0	0	0	111.4	I162 I430 R431 T436 L437 L438 I452 I456	I162-I434 HydrophobicContact CD1-CD1 4.47Å; I162-I434 HydrophobicContact CD1-CG1 3.9Å; I430-I434 HydrophobicContact CG2-CD1 3.81Å; I430-I434 HydrophobicContact CG2-CG1 4.46Å; I430-I434 WeakPolarHBondContact O-CB 3.38Å; I430-I434 WeakPolarHBondContact O-CG1 3.25Å; I430-I434 PolarHBondContact O-N 2.84Å; R431-I434 PolarHBondContact O-N 3.37Å; I434-T436 VanDerWaalsContact C-N 3.32Å; I434-T436 PolarHBondContact O-N 3.05Å; I434-L437 PolarHBondContact O-N 3.33Å; I434-L438 HydrophobicContact CG2-CD1 3.8Å; I434-L438 HydrophobicContact CG2-CG 4.43Å; I434-L438 PolarHBondContact O-N 2.91Å; I434-I452 HydrophobicContact CG2-CG2 4.19Å; I434-I456 HydrophobicContact CD1-CD1 3.98Å; I434-I456 HydrophobicContact CD1-CG1 4.05Å
435	T	82.9	Confident	81.6	Confident	42 Å²	42	64 Å²	64	26%	0.258	34%	0.34	S	S	.	.	H	α-helix	trans	-62.2	-43.1	179.6	-60.6	0	0	0	0	111.1	R431 S432 S433 L437 F439	R431-T435 VanDerWaalsContact O-CB 3.27Å; R431-T435 WeakPolarHBondContact O-CB 3.29Å; R431-T435 PolarHBondContact O-N 2.88Å; R431-T435 PolarHBondContact O-OG1 2.91Å; S432-T435 PolarHBondContact O-N 3.45Å; S433-T435 PolarHBondContact O-N 3.37Å; T435-L437 VanDerWaalsContact C-N 3.33Å; T435-L437 PolarHBondContact O-N 3.42Å; T435-F439 CarbonylContact O-C 3.25Å; T435-F439 WeakPolarHBondContact O-CA 3.4Å; T435-F439 WeakPolarHBondContact O-CB 3.45Å; T435-F439 PolarHBondContact O-N 3.13Å
436	T	77.1	Confident	81.7	Confident	79 Å²	79	69.7 Å²	69.7	49%	0.485	36%	0.36	S	S	.	.	H	α-helix	trans	-67.8	-33.4	178.7	-57.8	0	0	0	0	112.2	S432 S433 I434	S432-T436 WeakPolarHBondContact O-CB 3.1Å; S432-T436 PolarHBondContact O-N 2.78Å; S432-T436 PolarHBondContact O-OG1 3.2Å; S433-T436 PolarHBondContact O-N 3.4Å; I434-T436 VanDerWaalsContact C-N 3.32Å; I434-T436 PolarHBondContact O-N 3.05Å
437	L	78.8	Confident	81.8	Confident	67 Å²	67	73.9 Å²	73.9	35%	0.351	39%	0.386	S	S	.	.	H	α-helix	trans	-77.1	-48.2	179.6	-173	66	0	0	0	112.7	M155 F158 S433 I434 T435	M155-L437 HydrophobicContact CE-CD1 3.87Å; F158-L437 HydrophobicContact CD1-CD2 4.11Å; F158-L437 HydrophobicContact CE1-CD2 3.43Å; F158-L437 VanDerWaalsContact CE1-CD2 3.43Å; F158-L437 HydrophobicContact CE2-CB 4Å; F158-L437 HydrophobicContact CE2-CD2 3.89Å; F158-L437 HydrophobicContact CZ-CB 4.11Å; F158-L437 HydrophobicContact CZ-CD2 3.28Å; F158-L437 HydrophobicContact CZ-CG 4.29Å; S433-L437 WeakPolarHBondContact O-CB 3.21Å; S433-L437 PolarHBondContact O-N 3.34Å; I434-L437 PolarHBondContact O-N 3.33Å; T435-L437 VanDerWaalsContact C-N 3.33Å; T435-L437 PolarHBondContact O-N 3.42Å
438	L	81.6	Confident	81.8	Confident	116 Å²	116	76 Å²	76	61%	0.607	39%	0.394	S	S	*	.	H	α-helix	trans	-90.2	-26.3	-171.7	-63.9	179.3	0	0	0	113.9	I434	I434-L438 HydrophobicContact CG2-CD1 3.8Å; I434-L438 HydrophobicContact CG2-CG 4.43Å; I434-L438 PolarHBondContact O-N 2.91Å
439	F	82.4	Confident	82.1	Confident	56 Å²	56	73 Å²	73	25%	0.246	38%	0.381	C	S	.	.	S	Bend	trans	-133	34.9	-169.2	-55.2	-71.6	0	0	0	113	T435 G441 R442 I452	T435-F439 CarbonylContact O-C 3.25Å; T435-F439 WeakPolarHBondContact O-CA 3.4Å; T435-F439 WeakPolarHBondContact O-CB 3.45Å; T435-F439 PolarHBondContact O-N 3.13Å; F439-G441 PolarHBondContact O-N 3.35Å; F439-R442 PolarHBondContact O-N 3.46Å; F439-I452 HydrophobicContact CD2-CD1 4.36Å; F439-I452 HydrophobicContact CE2-CD1 4.07Å
440	K	74.6	Confident	82.7	Confident	177 Å²	177	75.7 Å²	75.7	77%	0.77	39%	0.394	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.4	123.8	177.9	-167	179.6	179.4	-173.4	0	110.6
441	G	69.8	Low	83	Confident	83 Å²	83	79.5 Å²	79.5	86%	0.856	42%	0.417	S	S	*	.	T	Hydrogen-bonded Turn	trans	80	12.5	175.2	0	0	0	0	0	116	F439	F439-G441 PolarHBondContact O-N 3.35Å
442	R	78.3	Confident	83.3	Confident	176 Å²	176	79.6 Å²	79.6	66%	0.664	42%	0.419	S	S	*	.	P	Polyproline II helix	trans	-96.6	142.6	169.8	-67.1	-165.7	177.9	-176.5	0.1	111.5	F439	F439-R442 PolarHBondContact O-N 3.46Å
443	D	80	Confident	84	Confident	148 Å²	148	77 Å²	77	79%	0.791	40%	0.4	S	S	*	.	P	Polyproline II helix	trans	-58.7	158.4	177.1	-62.1	-40.3	0	0	0	112.8	S445 R448	D443-S445 PolarHBondContact O-N 2.95Å; D443-R448 PolarHBondContact O-NH1 3.13Å
444	F	81.7	Confident	84.7	Confident	110 Å²	110	78.3 Å²	78.3	48%	0.482	41%	0.412	S	S	.	.	P	Polyproline II helix	trans	-62.7	131.4	176.1	179.1	-90.1	0	0	0	110.6	W446 H449	F444-W446 AromaticContact CE1-CD1 3.93Å; F444-W446 AromaticContact CE1-CD2 3.84Å; F444-W446 HydrophobicContact CE1-CD2 3.84Å; F444-W446 HydrophobicContact CE1-CE3 4.41Å; F444-W446 AromaticContact CE1-CG 3.87Å; F444-W446 HydrophobicContact CE1-CG 3.87Å; F444-W446 HydrophobicContact CZ-CD2 4.08Å; F444-W446 HydrophobicContact CZ-CE3 4.19Å; F444-W446 HydrophobicContact CZ-CG 4.45Å; F444-H449 HydrophobicContact CE2-CB 4.21Å; F444-H449 AromaticContact CE2-CE1 3.98Å; F444-H449 AromaticContact CE2-CG 3.96Å; F444-H449 AromaticContact CE2-ND1 3.56Å; F444-H449 HydrophobicContact CZ-CB 4.13Å
445	S	87.6	Confident	85.2	Confident	35 Å²	35	82 Å²	82	25%	0.245	43%	0.431	C	S	.	.			trans	-135.3	128.8	173.8	47.1	0	0	0	0	109.8	D443 T447 R448 H449	D443-S445 PolarHBondContact O-N 2.95Å; S445-T447 VanDerWaalsContact C-N 3.29Å; S445-T447 PolarHBondContact O-N 3.05Å; S445-R448 PolarHBondContact O-N 3.02Å; S445-R448 WeakPolarHBondContact OG-CB 3.37Å; S445-R448 WeakPolarHBondContact OG-CD 3.18Å; S445-R448 PolarHBondContact OG-NH1 2.96Å; S445-H449 WeakPolarHBondContact O-CB 3.29Å; S445-H449 PolarHBondContact O-N 3.32Å
446	W	87.3	Confident	85.8	Confident	139 Å²	139	80.7 Å²	80.7	53%	0.527	42%	0.422	S	S	.	.	H	α-helix	trans	-62.1	-36.2	-178.9	-81.7	111.6	0	0	0	112.8	K220 F444 H449 L450	K220-W446 HydrophobicContact CD-CH2 3.77Å; K220-W446 HydrophobicContact CD-CZ2 3.72Å; K220-W446 VanDerWaalsContact CE-CE2 3.47Å; K220-W446 VanDerWaalsContact CE-CH2 3.47Å; K220-W446 HydrophobicContact CG-CH2 3.81Å; K220-W446 HydrophobicContact CG-CZ2 4.28Å; K220-W446 HydrophobicContact CG-CZ3 4.37Å; F444-W446 AromaticContact CE1-CD1 3.93Å; F444-W446 AromaticContact CE1-CD2 3.84Å; F444-W446 HydrophobicContact CE1-CD2 3.84Å; F444-W446 HydrophobicContact CE1-CE3 4.41Å; F444-W446 AromaticContact CE1-CG 3.87Å; F444-W446 HydrophobicContact CE1-CG 3.87Å; F444-W446 HydrophobicContact CZ-CD2 4.08Å; F444-W446 HydrophobicContact CZ-CE3 4.19Å; F444-W446 HydrophobicContact CZ-CG 4.45Å; W446-H449 WeakPolarHBondContact O-CB 3.47Å; W446-H449 PolarHBondContact O-N 3.46Å; W446-L450 WeakPolarHBondContact O-CB 3.39Å; W446-L450 PolarHBondContact O-N 2.63Å
447	T	89.6	Confident	86.6	Confident	103 Å²	103	77.2 Å²	77.2	63%	0.632	40%	0.401	S	S	*	.	H	α-helix	trans	-63.5	-48.3	178.1	50.4	0	0	0	0	111.6	S445 H449 L450 V451	S445-T447 VanDerWaalsContact C-N 3.29Å; S445-T447 PolarHBondContact O-N 3.05Å; T447-H449 VanDerWaalsContact C-N 3.32Å; T447-H449 PolarHBondContact O-N 2.91Å; T447-L450 PolarHBondContact O-N 2.92Å; T447-V451 WeakPolarHBondContact O-CB 3.45Å; T447-V451 WeakPolarHBondContact O-CG2 3.26Å; T447-V451 PolarHBondContact O-N 2.61Å
448	R	89	Confident	87.4	Confident	45 Å²	45	76.8 Å²	76.8	17%	0.17	41%	0.407	C	S	.	.	H	α-helix	trans	-61	-42.7	173.7	-82.7	174.5	41.3	-125.4	-3.8	111.7	D443 S445 L450 V451 I452	D443-R448 PolarHBondContact O-NH1 3.13Å; S445-R448 PolarHBondContact O-N 3.02Å; S445-R448 WeakPolarHBondContact OG-CB 3.37Å; S445-R448 WeakPolarHBondContact OG-CD 3.18Å; S445-R448 PolarHBondContact OG-NH1 2.96Å; R448-L450 VanDerWaalsContact C-N 3.33Å; R448-L450 PolarHBondContact O-N 3.07Å; R448-V451 PolarHBondContact O-N 3.19Å; R448-I452 WeakPolarHBondContact O-CB 3.43Å; R448-I452 WeakPolarHBondContact O-CD1 3.29Å; R448-I452 WeakPolarHBondContact O-CG1 3.43Å; R448-I452 PolarHBondContact O-N 3.03Å
449	H	88.3	Confident	88.1	Confident	21 Å²	21	76.4 Å²	76.4	10%	0.097	40%	0.401	C	S	.	.	H	α-helix	trans	-59.1	-45.7	179.9	-165.7	84.8	0	0	0	111.9	R431 F444 S445 W446 T447 A453	R431-H449 PolarHBondContact NE-CE1 3.37Å; R431-H449 PolarHBondContact NH1-CE1 3.41Å; R431-H449 PolarHBondContact NH1-NE2 3.22Å; R431-H449 PolarHBondContact NH2-CE1 2.67Å; F444-H449 HydrophobicContact CE2-CB 4.21Å; F444-H449 AromaticContact CE2-CE1 3.98Å; F444-H449 AromaticContact CE2-CG 3.96Å; F444-H449 AromaticContact CE2-ND1 3.56Å; F444-H449 HydrophobicContact CZ-CB 4.13Å; S445-H449 WeakPolarHBondContact O-CB 3.29Å; S445-H449 PolarHBondContact O-N 3.32Å; W446-H449 WeakPolarHBondContact O-CB 3.47Å; W446-H449 PolarHBondContact O-N 3.46Å; T447-H449 VanDerWaalsContact C-N 3.32Å; T447-H449 PolarHBondContact O-N 2.91Å; H449-A453 WeakPolarHBondContact O-CB 3.31Å; H449-A453 PolarHBondContact O-N 3.29Å
450	L	92.6	Very high	88.7	Confident	77 Å²	77	73.8 Å²	73.8	40%	0.403	39%	0.389	S	S	.	.	H	α-helix	trans	-66.2	-50	175.9	176.9	65.3	0	0	0	112.2	L214 L218 W446 T447 R448 I452 A453 A454	L214-L450 HydrophobicContact CD1-CD1 4.36Å; L214-L450 HydrophobicContact CD2-CD1 4.39Å; L218-L450 HydrophobicContact CD1-CD1 3.57Å; L218-L450 HydrophobicContact CD2-CB 4.13Å; L218-L450 HydrophobicContact CD2-CD1 3.71Å; L218-L450 HydrophobicContact CG-CD1 4.23Å; W446-L450 WeakPolarHBondContact O-CB 3.39Å; W446-L450 PolarHBondContact O-N 2.63Å; T447-L450 PolarHBondContact O-N 2.92Å; R448-L450 VanDerWaalsContact C-N 3.33Å; R448-L450 PolarHBondContact O-N 3.07Å; L450-I452 PolarHBondContact O-N 3.46Å; L450-A453 PolarHBondContact O-N 3.05Å; L450-A454 VanDerWaalsContact O-CB 3.31Å; L450-A454 WeakPolarHBondContact O-CB 3.31Å; L450-A454 PolarHBondContact O-N 3.37Å
451	V	93.2	Very high	89.8	Confident	80 Å²	80	65.8 Å²	65.8	49%	0.485	36%	0.355	S	S	.	.	H	α-helix	trans	-62	-43.5	-176.9	169.1	0	0	0	0	111.2	T447 R448 A454 L455	T447-V451 WeakPolarHBondContact O-CB 3.45Å; T447-V451 WeakPolarHBondContact O-CG2 3.26Å; T447-V451 PolarHBondContact O-N 2.61Å; R448-V451 PolarHBondContact O-N 3.19Å; V451-A454 PolarHBondContact O-N 3.2Å; V451-L455 HydrophobicContact CG1-CD1 3.77Å; V451-L455 HydrophobicContact CG1-CG 4.24Å; V451-L455 WeakPolarHBondContact O-CB 3.33Å; V451-L455 VanDerWaalsContact O-CG 3.23Å; V451-L455 WeakPolarHBondContact O-CG 3.33Å; V451-L455 PolarHBondContact O-N 3.42Å
452	I	92.4	Very high	91	Very high	16 Å²	16	67 Å²	67	8%	0.082	34%	0.34	C	S	.	.	H	α-helix	trans	-63.2	-46.9	178.2	-66.4	166.5	0	0	0	110.4	R431 I434 F439 R448 L450 A454 L455 I456	R431-I452 HydrophobicContact CB-CG2 4.38Å; R431-I452 HydrophobicContact CG-CG2 3.9Å; I434-I452 HydrophobicContact CG2-CG2 4.19Å; F439-I452 HydrophobicContact CD2-CD1 4.36Å; F439-I452 HydrophobicContact CE2-CD1 4.07Å; R448-I452 WeakPolarHBondContact O-CB 3.43Å; R448-I452 WeakPolarHBondContact O-CD1 3.29Å; R448-I452 WeakPolarHBondContact O-CG1 3.43Å; R448-I452 PolarHBondContact O-N 3.03Å; L450-I452 PolarHBondContact O-N 3.46Å; I452-A454 PolarHBondContact O-N 2.88Å; I452-L455 PolarHBondContact O-N 3.38Å; I452-I456 HydrophobicContact CG2-CD1 3.7Å; I452-I456 HydrophobicContact CG2-CG1 4.42Å; I452-I456 WeakPolarHBondContact O-CD1 3.38Å; I452-I456 VanDerWaalsContact O-CG1 3.24Å; I452-I456 WeakPolarHBondContact O-CG1 3.11Å; I452-I456 PolarHBondContact O-N 3.43Å
453	A	92.8	Very high	91.7	Very high	0 Å²	0	61 Å²	61	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-61.8	-44.8	178.4	0	0	0	0	0	111.9	L214 L218 L427 H449 L450 I456 L457	L214-A453 HydrophobicContact CD1-CB 4.02Å; L218-A453 HydrophobicContact CD2-CB 4.39Å; L427-A453 HydrophobicContact CD2-CB 4.04Å; H449-A453 WeakPolarHBondContact O-CB 3.31Å; H449-A453 PolarHBondContact O-N 3.29Å; L450-A453 PolarHBondContact O-N 3.05Å; A453-I456 PolarHBondContact O-N 2.66Å; A453-L457 WeakPolarHBondContact O-CB 3.31Å; A453-L457 PolarHBondContact O-N 2.83Å
454	A	94.6	Very high	92.4	Very high	36 Å²	36	54 Å²	54	30%	0.298	28%	0.283	S	S	.	.	H	α-helix	trans	-63	-41.6	177.7	0	0	0	0	0	112.4	L214 L450 V451 I452 L457 A458	L214-A454 HydrophobicContact CD1-CB 4.36Å; L450-A454 VanDerWaalsContact O-CB 3.31Å; L450-A454 WeakPolarHBondContact O-CB 3.31Å; L450-A454 PolarHBondContact O-N 3.37Å; V451-A454 PolarHBondContact O-N 3.2Å; I452-A454 PolarHBondContact O-N 2.88Å; A454-L457 PolarHBondContact O-N 2.7Å; A454-A458 WeakPolarHBondContact O-CB 3.31Å; A454-A458 PolarHBondContact O-N 2.91Å
455	L	95	Very high	93	Very high	116 Å²	116	51.4 Å²	51.4	61%	0.607	27%	0.274	S	S	*	.	H	α-helix	trans	-66.8	-43.6	177.8	-73.9	173.8	0	0	0	112.4	V451 I452 L457 A458 F459	V451-L455 HydrophobicContact CG1-CD1 3.77Å; V451-L455 HydrophobicContact CG1-CG 4.24Å; V451-L455 WeakPolarHBondContact O-CB 3.33Å; V451-L455 VanDerWaalsContact O-CG 3.23Å; V451-L455 WeakPolarHBondContact O-CG 3.33Å; V451-L455 PolarHBondContact O-N 3.42Å; I452-L455 PolarHBondContact O-N 3.38Å; L455-L457 VanDerWaalsContact C-N 3.31Å; L455-L457 PolarHBondContact O-N 3.4Å; L455-A458 PolarHBondContact O-N 2.93Å; L455-F459 WeakPolarHBondContact O-CB 3.12Å; L455-F459 PolarHBondContact O-N 3.42Å
456	I	94.3	Very high	93.2	Very high	14 Å²	14	56.7 Å²	56.7	7%	0.072	29%	0.292	C	S	.	.	H	α-helix	trans	-59.9	-46.6	175.5	-66.6	161.7	0	0	0	109.8	M169 L427 I430 R431 I434 I452 A453 F459 N460	M169-I456 HydrophobicContact CE-CG2 4.09Å; M169-I456 HydrophobicContact SD-CG2 4.18Å; L427-I456 HydrophobicContact CD1-CG2 4.44Å; L427-I456 HydrophobicContact CG-CG2 4.39Å; I430-I456 HydrophobicContact CB-CD1 4.22Å; I430-I456 HydrophobicContact CD1-CG2 4.16Å; I430-I456 HydrophobicContact CG2-CD1 3.66Å; I430-I456 HydrophobicContact CG2-CG1 4.07Å; I430-I456 HydrophobicContact CG2-CG2 4.23Å; R431-I456 HydrophobicContact CB-CD1 4.27Å; I434-I456 HydrophobicContact CD1-CD1 3.98Å; I434-I456 HydrophobicContact CD1-CG1 4.05Å; I452-I456 HydrophobicContact CG2-CD1 3.7Å; I452-I456 HydrophobicContact CG2-CG1 4.42Å; I452-I456 WeakPolarHBondContact O-CD1 3.38Å; I452-I456 VanDerWaalsContact O-CG1 3.24Å; I452-I456 WeakPolarHBondContact O-CG1 3.11Å; I452-I456 PolarHBondContact O-N 3.43Å; A453-I456 PolarHBondContact O-N 2.66Å; I456-F459 PolarHBondContact O-N 3.47Å; I456-N460 PolarHBondContact O-N 2.98Å; I456-N460 PolarHBondContact O-ND2 3.46Å
457	L	95.4	Very high	93.3	Very high	6 Å²	6	51.6 Å²	51.6	3%	0.031	28%	0.276	C	S	.	.	H	α-helix	trans	-68.3	-40.7	-177.8	-171.2	59	0	0	0	111.8	M169 L173 S209 I213 L214 A453 A454 L455 N460 N461	M169-L457 HydrophobicContact SD-CD1 4.45Å; L173-L457 HydrophobicContact CD1-CD1 4.08Å; S209-L457 WeakPolarHBondContact O-CD2 3.26Å; I213-L457 HydrophobicContact CB-CD2 4.38Å; I213-L457 HydrophobicContact CG2-CD1 4.03Å; I213-L457 HydrophobicContact CG2-CD2 4.08Å; L214-L457 HydrophobicContact CB-CD2 3.92Å; A453-L457 WeakPolarHBondContact O-CB 3.31Å; A453-L457 PolarHBondContact O-N 2.83Å; A454-L457 PolarHBondContact O-N 2.7Å; L455-L457 VanDerWaalsContact C-N 3.31Å; L455-L457 PolarHBondContact O-N 3.4Å; L457-N460 PolarHBondContact O-N 2.86Å; L457-N461 PolarHBondContact O-N 2.98Å; L457-N461 PolarHBondContact O-ND2 2.97Å
458	A	95.7	Very high	93	Very high	58 Å²	58	49.7 Å²	49.7	48%	0.479	27%	0.266	S	S	.	.	H	α-helix	trans	-62	-42.9	174.9	0	0	0	0	0	111.8	A454 L455 N461 M462	A454-A458 WeakPolarHBondContact O-CB 3.31Å; A454-A458 PolarHBondContact O-N 2.91Å; L455-A458 PolarHBondContact O-N 2.93Å; A458-N461 PolarHBondContact O-N 3.16Å; A458-M462 PolarHBondContact O-N 3.33Å
459	F	95.8	Very high	93	Very high	109 Å²	109	49.6 Å²	49.6	48%	0.478	27%	0.27	S	S	.	.	H	α-helix	trans	-60.6	-45.5	175.1	176	-99.7	0	0	0	112.2	I166 L455 I456 M462 L463	I166-F459 HydrophobicContact CD1-CD1 4.29Å; I166-F459 HydrophobicContact CD1-CE1 3.96Å; I166-F459 HydrophobicContact CG2-CD1 4.44Å; I166-F459 HydrophobicContact CG2-CE1 3.91Å; L455-F459 WeakPolarHBondContact O-CB 3.12Å; L455-F459 PolarHBondContact O-N 3.42Å; I456-F459 PolarHBondContact O-N 3.47Å; F459-M462 WeakPolarHBondContact O-CB 3.37Å; F459-M462 PolarHBondContact O-N 3.13Å; F459-L463 HydrophobicContact CE1-CD1 4.42Å; F459-L463 PolarHBondContact O-N 3.18Å
460	N	95.7	Very high	93.1	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-66.5	-39.1	177.8	-80.5	-94.3	0	0	0	112.3	I166 M169 S170 L173 I456 L457 M462 L463 V464	I166-N460 PolarHBondContact O-OD1 2.91Å; M169-N460 HydrophobicContact CG-CB 4.23Å; M169-N460 HydrophobicContact SD-CB 4.11Å; S170-N460 PolarHBondContact N-OD1 3.11Å; S170-N460 PolarHBondContact OG-OD1 3.38Å; L173-N460 HydrophobicContact CD1-CB 3.81Å; I456-N460 PolarHBondContact O-N 2.98Å; I456-N460 PolarHBondContact O-ND2 3.46Å; L457-N460 PolarHBondContact O-N 2.86Å; N460-M462 VanDerWaalsContact C-N 3.34Å; N460-M462 PolarHBondContact O-N 3.3Å; N460-L463 PolarHBondContact O-N 3.39Å; N460-V464 WeakPolarHBondContact O-CG2 3.36Å; N460-V464 PolarHBondContact O-N 3.13Å
461	N	95.9	Very high	93.1	Very high	10 Å²	10	47.4 Å²	47.4	5%	0.053	26%	0.256	C	S	.	.	H	α-helix	trans	-61	-44.6	174.2	-86.2	-91.5	0	0	0	111.3	V205 S209 L457 A458 L463 V464 I465	V205-N461 PolarHBondContact O-OD1 3Å; S209-N461 WeakPolarHBondContact CB-ND2 3.45Å; S209-N461 PolarHBondContact OG-ND2 3.37Å; S209-N461 PolarHBondContact OG-OD1 3.44Å; L457-N461 PolarHBondContact O-N 2.98Å; L457-N461 PolarHBondContact O-ND2 2.97Å; A458-N461 PolarHBondContact O-N 3.16Å; N461-L463 VanDerWaalsContact C-N 3.34Å; N461-L463 PolarHBondContact O-N 3.15Å; N461-V464 PolarHBondContact O-N 3.12Å; N461-I465 WeakPolarHBondContact O-CD1 3.32Å; N461-I465 VanDerWaalsContact O-CG1 3.24Å; N461-I465 WeakPolarHBondContact O-CG1 3.42Å; N461-I465 PolarHBondContact O-N 2.97Å
462	M	95.3	Very high	93	Very high	109 Å²	109	44.5 Å²	44.5	54%	0.537	24%	0.238	S	C	.	.	H	α-helix	trans	-57.5	-49.3	175.6	-172	-154.4	169.1	0	0	110.7	A458 F459 N460 V464 I465 F466	A458-M462 PolarHBondContact O-N 3.33Å; F459-M462 WeakPolarHBondContact O-CB 3.37Å; F459-M462 PolarHBondContact O-N 3.13Å; N460-M462 VanDerWaalsContact C-N 3.34Å; N460-M462 PolarHBondContact O-N 3.3Å; M462-V464 PolarHBondContact O-N 3.29Å; M462-I465 PolarHBondContact O-N 3.27Å; M462-F466 HydrophobicContact CE-CD2 3.85Å; M462-F466 HydrophobicContact CE-CE2 3.48Å; M462-F466 VanDerWaalsContact CE-CE2 3.48Å; M462-F466 HydrophobicContact CE-CZ 4.44Å; M462-F466 HydrophobicContact CG-CD2 3.8Å; M462-F466 HydrophobicContact CG-CE2 3.57Å; M462-F466 WeakPolarHBondContact O-CD2 3.26Å; M462-F466 PolarHBondContact O-N 3.33Å; M462-F466 HydrophobicContact SD-CE2 4.41Å
463	L	94	Very high	93.1	Very high	50 Å²	50	44.2 Å²	44.2	26%	0.262	24%	0.236	S	C	.	.	H	α-helix	trans	-55.1	-50.3	178.8	-171.6	161.7	0	0	0	111.1	I166 F459 N460 N461 I465 F466 V467 I473	I166-L463 HydrophobicContact CG2-CD1 4.22Å; F459-L463 HydrophobicContact CE1-CD1 4.42Å; F459-L463 PolarHBondContact O-N 3.18Å; N460-L463 PolarHBondContact O-N 3.39Å; N461-L463 VanDerWaalsContact C-N 3.34Å; N461-L463 PolarHBondContact O-N 3.15Å; L463-I465 VanDerWaalsContact C-N 3.31Å; L463-I465 PolarHBondContact O-N 3.44Å; L463-F466 PolarHBondContact O-N 3.18Å; L463-V467 HydrophobicContact CD2-CB 4.38Å; L463-V467 HydrophobicContact CD2-CG2 3.56Å; L463-V467 HydrophobicContact CG-CG2 4.23Å; L463-V467 WeakPolarHBondContact O-CB 3.49Å; L463-V467 VanDerWaalsContact O-CG2 3.3Å; L463-V467 WeakPolarHBondContact O-CG2 3.42Å; L463-V467 PolarHBondContact O-N 3.38Å; L463-I473 HydrophobicContact CD2-CD1 4.38Å
464	V	94.4	Very high	93.1	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-66.9	-29.6	-177.8	169.9	0	0	0	0	113.5	S170 L173 F174 K177 N460 N461 M462 F466	S170-V464 WeakPolarHBondContact O-CG2 3.2Å; L173-V464 HydrophobicContact CB-CG1 4.46Å; L173-V464 HydrophobicContact CB-CG2 3.94Å; F174-V464 HydrophobicContact CB-CG1 4.07Å; F174-V464 HydrophobicContact CD2-CG1 4.29Å; K177-V464 HydrophobicContact CB-CG1 4.22Å; K177-V464 HydrophobicContact CD-CG1 3.8Å; K177-V464 PolarHBondContact NZ-O 3.37Å; N460-V464 WeakPolarHBondContact O-CG2 3.36Å; N460-V464 PolarHBondContact O-N 3.13Å; N461-V464 PolarHBondContact O-N 3.12Å; M462-V464 PolarHBondContact O-N 3.29Å; V464-F466 VanDerWaalsContact C-N 3.35Å
465	I	93.6	Very high	93	Very high	56 Å²	56	42.6 Å²	42.6	29%	0.287	22%	0.222	S	C	.	.	H	α-helix	trans	-66.6	-40.6	175.4	-71.6	165.4	0	0	0	110.5	K177 N202 V206 N461 M462 L463	K177-I465 PolarHBondContact NZ-O 3.18Å; N202-I465 HydrophobicContact CB-CG1 4.31Å; V206-I465 HydrophobicContact CG2-CD1 4.36Å; N461-I465 WeakPolarHBondContact O-CD1 3.32Å; N461-I465 VanDerWaalsContact O-CG1 3.24Å; N461-I465 WeakPolarHBondContact O-CG1 3.42Å; N461-I465 PolarHBondContact O-N 2.97Å; M462-I465 PolarHBondContact O-N 3.27Å; L463-I465 VanDerWaalsContact C-N 3.31Å; L463-I465 PolarHBondContact O-N 3.44Å
466	F	91.3	Very high	93	Very high	146 Å²	146	40.8 Å²	40.8	64%	0.64	21%	0.21	S	C	*	.	H	α-helix	trans	-88.4	-24.3	-176.8	-68.8	-65.4	0	0	0	114.8	M462 L463 V464 P468	M462-F466 HydrophobicContact CE-CD2 3.85Å; M462-F466 HydrophobicContact CE-CE2 3.48Å; M462-F466 VanDerWaalsContact CE-CE2 3.48Å; M462-F466 HydrophobicContact CE-CZ 4.44Å; M462-F466 HydrophobicContact CG-CD2 3.8Å; M462-F466 HydrophobicContact CG-CE2 3.57Å; M462-F466 WeakPolarHBondContact O-CD2 3.26Å; M462-F466 PolarHBondContact O-N 3.33Å; M462-F466 HydrophobicContact SD-CE2 4.41Å; L463-F466 PolarHBondContact O-N 3.18Å; V464-F466 VanDerWaalsContact C-N 3.35Å; F466-P468 WeakPolarHBondContact O-CD 3.15Å
467	V	89.4	Confident	93.1	Very high	31 Å²	31	40.7 Å²	40.7	19%	0.188	21%	0.209	C	C	.	.			trans	-73.8	124	178.4	169.9	0	0	0	0	110.1	L463 T469 I473	L463-V467 HydrophobicContact CD2-CB 4.38Å; L463-V467 HydrophobicContact CD2-CG2 3.56Å; L463-V467 HydrophobicContact CG-CG2 4.23Å; L463-V467 WeakPolarHBondContact O-CB 3.49Å; L463-V467 VanDerWaalsContact O-CG2 3.3Å; L463-V467 WeakPolarHBondContact O-CG2 3.42Å; L463-V467 PolarHBondContact O-N 3.38Å; V467-T469 WeakPolarHBondContact CG1-O 3.3Å; V467-I473 HydrophobicContact CB-CD1 4.49Å; V467-I473 HydrophobicContact CG1-CD1 3.96Å; V467-I473 HydrophobicContact CG1-CG1 3.68Å
468	P	85.2	Confident	93.1	Very high	64 Å²	64	40.4 Å²	40.4	42%	0.416	21%	0.208	S	C	.	.			trans	-79.2	-32.9	-175.5	30.4	-35.2	0	0	0	112.9	F466 P538	F466-P468 WeakPolarHBondContact O-CD 3.15Å; P468-P538 HydrophobicContact CG-CB 3.87Å
469	T	88.6	Confident	93.1	Very high	42 Å²	42	37.7 Å²	37.7	26%	0.258	19%	0.185	S	C	.	.			trans	-134.4	139.7	-175.8	80.1	0	0	0	0	112.1	V467 R471 D472	V467-T469 WeakPolarHBondContact CG1-O 3.3Å; T469-R471 PolarHBondContact O-N 3.41Å; T469-D472 PolarHBondContact O-N 3.26Å; T469-D472 PolarHBondContact OG1-N 3.5Å; T469-D472 PolarHBondContact OG1-OD2 2.72Å
470	I	90.6	Very high	93.1	Very high	4 Å²	4	33 Å²	33	2%	0.021	17%	0.166	C	C	.	.	H	α-helix	trans	-63.6	-27.6	174.5	-161.3	171.1	0	0	0	112.1	F174 I175 A392 E393 D472 I473 F474	F174-I470 HydrophobicContact CB-CD1 4.46Å; F174-I470 HydrophobicContact CD1-CB 3.73Å; F174-I470 HydrophobicContact CD1-CD1 3.99Å; F174-I470 HydrophobicContact CD1-CG1 4.09Å; F174-I470 HydrophobicContact CE1-CB 3.72Å; F174-I470 HydrophobicContact CE1-CG2 4.4Å; F174-I470 HydrophobicContact CG-CB 4.16Å; F174-I470 HydrophobicContact CG-CD1 4.44Å; F174-I470 HydrophobicContact CG-CG1 4.28Å; F174-I470 HydrophobicContact CZ-CB 4.12Å; I175-I470 HydrophobicContact CG1-CD1 4.17Å; A392-I470 HydrophobicContact CB-CG2 3.95Å; E393-I470 HydrophobicContact CB-CG2 4.48Å; I470-D472 VanDerWaalsContact C-N 3.28Å; I470-D472 PolarHBondContact O-N 3.44Å; I470-I473 WeakPolarHBondContact O-CB 3.32Å; I470-I473 PolarHBondContact O-N 3.22Å; I470-I473 VanDerWaalsContact O-N 3.15Å; I470-F474 HydrophobicContact CD1-CE1 4.18Å; I470-F474 HydrophobicContact CD1-CE2 3.86Å; I470-F474 HydrophobicContact CD1-CZ 3.45Å; I470-F474 VanDerWaalsContact CD1-CZ 3.45Å; I470-F474 HydrophobicContact CG1-CD2 4.33Å; I470-F474 HydrophobicContact CG1-CE1 3.98Å; I470-F474 HydrophobicContact CG1-CE2 3.76Å; I470-F474 HydrophobicContact CG1-CZ 3.57Å; I470-F474 HydrophobicContact CG2-CE2 4.29Å; I470-F474 PolarHBondContact O-N 3.41Å
471	R	91.7	Very high	93.1	Very high	49 Å²	49	33 Å²	33	19%	0.185	17%	0.166	C	C	.	.	H	α-helix	trans	-56.6	-41.8	175.3	178.9	-168.8	63.4	-160.3	-7.2	111.6	Y101 Q327 Y330 A392 T469 I473 F474 G475	Y101-R471 HydrophobicContact CE1-CG 4.06Å; Y101-R471 VanDerWaalsContact OH-CD 3.31Å; Y101-R471 WeakPolarHBondContact OH-CD 3.43Å; Y101-R471 PolarHBondContact OH-NH1 2.98Å; Q327-R471 VanDerWaalsContact CD-NH1 3.33Å; Y330-R471 HydrophobicContact CD1-CG 3.82Å; Y330-R471 HydrophobicContact CE1-CG 4.42Å; Y330-R471 HydrophobicContact CG-CG 4.08Å; A392-R471 HydrophobicContact CB-CB 3.97Å; T469-R471 PolarHBondContact O-N 3.41Å; R471-I473 VanDerWaalsContact C-N 3.29Å; R471-I473 PolarHBondContact O-N 2.97Å; R471-F474 PolarHBondContact O-N 2.93Å; R471-G475 PolarHBondContact O-N 3.41Å
472	D	91.6	Very high	93.1	Very high	18 Å²	18	32.5 Å²	32.5	10%	0.096	16%	0.164	C	C	.	.	H	α-helix	trans	-65.5	-36.1	-179.5	-63.2	-41.4	0	0	0	111.4	T469 I470 F476 W533	T469-D472 PolarHBondContact O-N 3.26Å; T469-D472 PolarHBondContact OG1-N 3.5Å; T469-D472 PolarHBondContact OG1-OD2 2.72Å; I470-D472 VanDerWaalsContact C-N 3.28Å; I470-D472 PolarHBondContact O-N 3.44Å; D472-F476 VanDerWaalsContact O-CB 3.3Å; D472-F476 WeakPolarHBondContact O-CB 3.33Å; D472-F476 PolarHBondContact O-N 3.03Å; D472-W533 HydrophobicContact CB-CZ2 4.32Å; D472-W533 PolarHBondContact OD1-NE1 3.05Å
473	I	93.4	Very high	93.2	Very high	10 Å²	10	27.3 Å²	27.3	5%	0.051	14%	0.138	C	C	.	.	H	α-helix	trans	-63	-53.2	173.7	-51.7	-178.5	0	0	0	109.7	F174 L463 V467 I470 R471 G475 I477	F174-I473 HydrophobicContact CB-CD1 4.49Å; F174-I473 HydrophobicContact CD2-CD1 4.22Å; L463-I473 HydrophobicContact CD2-CD1 4.38Å; V467-I473 HydrophobicContact CB-CD1 4.49Å; V467-I473 HydrophobicContact CG1-CD1 3.96Å; V467-I473 HydrophobicContact CG1-CG1 3.68Å; I470-I473 WeakPolarHBondContact O-CB 3.32Å; I470-I473 PolarHBondContact O-N 3.22Å; I470-I473 VanDerWaalsContact O-N 3.15Å; R471-I473 VanDerWaalsContact C-N 3.29Å; R471-I473 PolarHBondContact O-N 2.97Å; I473-G475 VanDerWaalsContact C-N 3.35Å; I473-G475 PolarHBondContact O-N 3.26Å; I473-I477 HydrophobicContact CG2-CG1 4.2Å; I473-I477 VanDerWaalsContact O-CB 3.28Å; I473-I477 WeakPolarHBondContact O-CB 3.15Å; I473-I477 WeakPolarHBondContact O-CG1 3.48Å; I473-I477 PolarHBondContact O-N 3.29Å
474	F	93.4	Very high	93.3	Very high	2 Å²	2	26.8 Å²	26.8	1%	0.009	14%	0.135	C	C	.	.	H	α-helix	trans	-63.2	-41.2	-178.9	-63.6	-23	0	0	0	112.5	S94 I334 F337 I470 R471 G478	S94-F474 WeakPolarHBondContact O-CZ 3.17Å; S94-F474 VanDerWaalsContact OG-CE1 3.28Å; S94-F474 WeakPolarHBondContact OG-CE1 3.11Å; I334-F474 HydrophobicContact CB-CB 4.47Å; I334-F474 HydrophobicContact CG1-CB 3.69Å; F337-F474 AromaticContact CD1-CD1 3.57Å; F337-F474 HydrophobicContact CD1-CD1 3.57Å; F337-F474 AromaticContact CD1-CE1 3.96Å; F337-F474 HydrophobicContact CD1-CE1 3.96Å; F337-F474 HydrophobicContact CD1-CG 4.21Å; F337-F474 AromaticContact CE1-CD1 3.37Å; F337-F474 HydrophobicContact CE1-CD1 3.37Å; F337-F474 AromaticContact CE1-CE1 3.35Å; F337-F474 HydrophobicContact CE1-CE1 3.35Å; F337-F474 HydrophobicContact CE1-CG 4.39Å; F337-F474 HydrophobicContact CE1-CZ 4.36Å; F337-F474 HydrophobicContact CG-CD1 4.26Å; F337-F474 AromaticContact CZ-CD1 3.9Å; F337-F474 HydrophobicContact CZ-CD1 3.9Å; F337-F474 AromaticContact CZ-CE1 3.91Å; F337-F474 HydrophobicContact CZ-CE1 3.91Å; I470-F474 HydrophobicContact CD1-CE1 4.18Å; I470-F474 HydrophobicContact CD1-CE2 3.86Å; I470-F474 HydrophobicContact CD1-CZ 3.45Å; I470-F474 VanDerWaalsContact CD1-CZ 3.45Å; I470-F474 HydrophobicContact CG1-CD2 4.33Å; I470-F474 HydrophobicContact CG1-CE1 3.98Å; I470-F474 HydrophobicContact CG1-CE2 3.76Å; I470-F474 HydrophobicContact CG1-CZ 3.57Å; I470-F474 HydrophobicContact CG2-CE2 4.29Å; I470-F474 PolarHBondContact O-N 3.41Å; R471-F474 PolarHBondContact O-N 2.93Å; F474-G478 WeakPolarHBondContact O-CA 3.34Å; F474-G478 PolarHBondContact O-N 2.96Å
475	G	93.2	Very high	93.4	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-60.2	-59.1	176.8	0	0	0	0	0	111.7	P333 R471 I473 G478 A479 I529	P333-G475 WeakPolarHBondContact CB-O 3.43Å; R471-G475 PolarHBondContact O-N 3.41Å; I473-G475 VanDerWaalsContact C-N 3.35Å; I473-G475 PolarHBondContact O-N 3.26Å; G475-G478 PolarHBondContact O-N 3.25Å; G475-A479 VanDerWaalsContact O-CB 3.22Å; G475-A479 WeakPolarHBondContact O-CB 3.28Å; G475-A479 PolarHBondContact O-N 3.14Å; G475-I529 VanDerWaalsContact C-CD1 3.48Å; G475-I529 VanDerWaalsContact O-CD1 3.3Å; G475-I529 WeakPolarHBondContact O-CD1 3.37Å
476	F	94.7	Very high	93.6	Very high	79 Å²	79	24.1 Å²	24.1	35%	0.346	12%	0.121	S	C	.	.	H	α-helix	trans	-64.3	-48.4	-175.2	178.7	-99.9	0	0	0	112.2	M163 D472 A479 S480 L526 W533	M163-F476 HydrophobicContact SD-CE1 4.14Å; D472-F476 VanDerWaalsContact O-CB 3.3Å; D472-F476 WeakPolarHBondContact O-CB 3.33Å; D472-F476 PolarHBondContact O-N 3.03Å; F476-A479 PolarHBondContact O-N 3.37Å; F476-S480 WeakPolarHBondContact O-CB 3.4Å; F476-S480 PolarHBondContact O-N 2.84Å; F476-S480 PolarHBondContact O-OG 3Å; F476-L526 HydrophobicContact CD2-CD2 4.15Å; F476-L526 HydrophobicContact CE2-CD2 4.24Å; F476-W533 HydrophobicContact CB-CH2 4.1Å; F476-W533 HydrophobicContact CB-CZ2 4.37Å; F476-W533 AromaticContact CD2-CH2 3.87Å; F476-W533 HydrophobicContact CD2-CH2 3.87Å; F476-W533 HydrophobicContact CD2-CZ3 4.43Å; F476-W533 HydrophobicContact CG-CH2 4.21Å
477	I	95.7	Very high	93.8	Very high	12 Å²	12	17.6 Å²	17.6	6%	0.062	9%	0.092	C	C	.	.	H	α-helix	trans	-69	-37.8	-177.9	-57.5	-68	0	0	0	110.8	M163 F337 I473 S480 A481 A482	M163-I477 HydrophobicContact CG-CD1 3.85Å; F337-I477 HydrophobicContact CD2-CB 4.11Å; F337-I477 HydrophobicContact CD2-CG2 3.72Å; F337-I477 HydrophobicContact CE2-CB 4.39Å; F337-I477 HydrophobicContact CE2-CG2 3.91Å; I473-I477 HydrophobicContact CG2-CG1 4.2Å; I473-I477 VanDerWaalsContact O-CB 3.28Å; I473-I477 WeakPolarHBondContact O-CB 3.15Å; I473-I477 WeakPolarHBondContact O-CG1 3.48Å; I473-I477 PolarHBondContact O-N 3.29Å; I477-S480 PolarHBondContact O-N 3.35Å; I477-A481 HydrophobicContact CG2-CB 4.13Å; I477-A481 PolarHBondContact O-N 2.72Å; I477-A482 PolarHBondContact O-N 3.36Å
478	G	95.3	Very high	94.2	Very high	0 Å²	0	17 Å²	17	0%	0	9%	0.088	C	C	.	.	I	π-helix	trans	-62.1	-48.2	174.4	0	0	0	0	0	113.3	P333 F474 G475 S480 T483	P333-G478 VanDerWaalsContact O-CA 3.26Å; P333-G478 WeakPolarHBondContact O-CA 3.49Å; F474-G478 WeakPolarHBondContact O-CA 3.34Å; F474-G478 PolarHBondContact O-N 2.96Å; G475-G478 PolarHBondContact O-N 3.25Å; G478-S480 VanDerWaalsContact C-N 3.3Å; G478-S480 PolarHBondContact O-N 2.9Å; G478-T483 PolarHBondContact O-N 2.84Å; G478-T483 PolarHBondContact O-OG1 2.66Å
479	A	95.7	Very high	94.7	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	7%	0.07	C	C	.	.	I	π-helix	trans	-69.3	-28.2	-179.3	0	0	0	0	0	112.7	P333 G475 F476 T483 M522 L526 I529	P333-A479 HydrophobicContact CB-CB 4.13Å; P333-A479 HydrophobicContact CG-CB 4.02Å; G475-A479 VanDerWaalsContact O-CB 3.22Å; G475-A479 WeakPolarHBondContact O-CB 3.28Å; G475-A479 PolarHBondContact O-N 3.14Å; F476-A479 PolarHBondContact O-N 3.37Å; A479-T483 WeakPolarHBondContact O-CB 3.14Å; A479-T483 PolarHBondContact O-OG1 3.21Å; A479-M522 WeakPolarHBondContact O-CG 3.36Å; A479-L526 HydrophobicContact CB-CD2 3.83Å; A479-L526 HydrophobicContact CB-CG 3.99Å; A479-I529 HydrophobicContact CB-CD1 3.67Å
480	S	96.6	Very high	95.1	Very high	11 Å²	11	12.3 Å²	12.3	8%	0.077	6%	0.058	C	C	.	.	I	π-helix	trans	-101.3	-84.3	-178.8	60.5	0	0	0	0	112.7	M163 F476 I477 G478 A482 T483 M484	M163-S480 VanDerWaalsContact CE-OG 3.26Å; M163-S480 WeakPolarHBondContact CE-OG 3.17Å; F476-S480 WeakPolarHBondContact O-CB 3.4Å; F476-S480 PolarHBondContact O-N 2.84Å; F476-S480 PolarHBondContact O-OG 3Å; I477-S480 PolarHBondContact O-N 3.35Å; G478-S480 VanDerWaalsContact C-N 3.3Å; G478-S480 PolarHBondContact O-N 2.9Å; S480-A482 PolarHBondContact O-N 3.48Å; S480-T483 PolarHBondContact O-N 2.88Å; S480-M484 WeakPolarHBondContact O-CB 3.32Å; S480-M484 PolarHBondContact O-N 3.44Å
481	A	96.4	Very high	95.4	Very high	0 Å²	0	12.1 Å²	12.1	0%	0	6%	0.057	C	C	.	.	I	π-helix	trans	-62.8	-48	-169.5	0	0	0	0	0	112.1	M163 Q164 I477 T483 M484 L485	M163-A481 HydrophobicContact CB-CB 3.99Å; M163-A481 HydrophobicContact CE-CB 3.55Å; M163-A481 HydrophobicContact CG-CB 4.01Å; Q164-A481 HydrophobicContact CB-CB 3.9Å; I477-A481 HydrophobicContact CG2-CB 4.13Å; I477-A481 PolarHBondContact O-N 2.72Å; A481-T483 VanDerWaalsContact C-N 3.32Å; A481-T483 PolarHBondContact O-N 3.01Å; A481-M484 PolarHBondContact O-N 3.29Å; A481-L485 WeakPolarHBondContact O-CB 3.36Å; A481-L485 VanDerWaalsContact O-CG 3.32Å; A481-L485 WeakPolarHBondContact O-CG 3.42Å; A481-L485 PolarHBondContact O-N 3.03Å
482	A	95.9	Very high	95.6	Very high	0 Å²	0	10.5 Å²	10.5	0%	0	5%	0.054	C	C	.	.	I	π-helix	trans	-63.9	-42.3	-179.4	0	0	0	0	0	110.7	A336 V340 I477 S480 M484 L485 I486	A336-A482 HydrophobicContact CB-CB 4.26Å; V340-A482 HydrophobicContact CB-CB 3.97Å; V340-A482 HydrophobicContact CG1-CB 4.2Å; V340-A482 HydrophobicContact CG2-CB 4.23Å; I477-A482 PolarHBondContact O-N 3.36Å; S480-A482 PolarHBondContact O-N 3.48Å; A482-M484 VanDerWaalsContact C-N 3.33Å; A482-M484 PolarHBondContact O-N 2.89Å; A482-L485 PolarHBondContact O-N 3.28Å; A482-I486 HydrophobicContact CB-CD1 4.28Å; A482-I486 VanDerWaalsContact O-CB 3.29Å; A482-I486 WeakPolarHBondContact O-CB 3.47Å; A482-I486 WeakPolarHBondContact O-CG1 3.29Å; A482-I486 PolarHBondContact O-N 3.42Å
483	T	96.2	Very high	95.8	Very high	0 Å²	0	9.7 Å²	9.7	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-62.2	-42.1	176.9	-62.2	0	0	0	0	112.1	G478 A479 S480 A481 L485 F487 I488 G518 F521 M522	G478-T483 PolarHBondContact O-N 2.84Å; G478-T483 PolarHBondContact O-OG1 2.66Å; A479-T483 WeakPolarHBondContact O-CB 3.14Å; A479-T483 PolarHBondContact O-OG1 3.21Å; S480-T483 PolarHBondContact O-N 2.88Å; A481-T483 VanDerWaalsContact C-N 3.32Å; A481-T483 PolarHBondContact O-N 3.01Å; T483-L485 VanDerWaalsContact C-N 3.33Å; T483-L485 PolarHBondContact O-N 3.14Å; T483-F487 HydrophobicContact CG2-CD2 3.91Å; T483-F487 WeakPolarHBondContact O-CB 3.25Å; T483-F487 PolarHBondContact O-N 3.23Å; T483-I488 PolarHBondContact O-N 3.26Å; T483-G518 WeakPolarHBondContact CG2-O 3.39Å; T483-F521 HydrophobicContact CG2-CD1 3.63Å; T483-F521 HydrophobicContact CG2-CE1 4.3Å; T483-F521 WeakPolarHBondContact OG1-CD1 3.44Å; T483-F521 WeakPolarHBondContact OG1-CE1 3.35Å; T483-M522 HydrophobicContact CG2-CB 3.7Å; T483-M522 HydrophobicContact CG2-CG 4.4Å
484	M	97.1	Very high	95.9	Very high	39 Å²	39	9.6 Å²	9.6	19%	0.192	5%	0.048	C	C	.	.	I	π-helix	trans	-62.4	-40.8	176	-173.6	62	75.2	0	0	111.9	S160 S480 A481 A482 I488 L489 M522	S160-M484 WeakPolarHBondContact OG-CG 3.28Å; S480-M484 WeakPolarHBondContact O-CB 3.32Å; S480-M484 PolarHBondContact O-N 3.44Å; A481-M484 PolarHBondContact O-N 3.29Å; A482-M484 VanDerWaalsContact C-N 3.33Å; A482-M484 PolarHBondContact O-N 2.89Å; M484-I488 HydrophobicContact CE-CD1 4.11Å; M484-I488 PolarHBondContact O-N 3.28Å; M484-I488 HydrophobicContact SD-CB 3.65Å; M484-I488 HydrophobicContact SD-CD1 4.01Å; M484-I488 HydrophobicContact SD-CG1 4.4Å; M484-I488 HydrophobicContact SD-CG2 3.55Å; M484-I488 VanDerWaalsContact SD-CG2 3.55Å; M484-L489 HydrophobicContact CG-CD1 3.79Å; M484-L489 HydrophobicContact CG-CD2 4.42Å; M484-L489 HydrophobicContact CG-CG 3.77Å; M484-L489 WeakPolarHBondContact O-CB 3.41Å; M484-L489 WeakPolarHBondContact O-CG 3.29Å; M484-L489 PolarHBondContact O-N 2.75Å; M484-L489 HydrophobicContact SD-CD1 4.43Å; M484-L489 HydrophobicContact SD-CD2 4Å; M484-L489 HydrophobicContact SD-CG 3.82Å; M484-M522 HydrophobicContact CE-CE 4.21Å; M484-M522 HydrophobicContact CE-SD 3.91Å
485	L	96.4	Very high	95.9	Very high	0 Å²	0	11.3 Å²	11.3	0%	0	6%	0.057	C	C	.	.	I	π-helix	trans	-80.8	-28.5	-177.6	-71	166.9	0	0	0	114.6	Y141 I161 Q164 V340 H342 P343 A481 A482 T483 L489 P490	Y141-L485 HydrophobicContact CE1-CD2 4.28Å; Y141-L485 HydrophobicContact CE2-CD2 4.43Å; I161-L485 HydrophobicContact CG1-CD2 3.94Å; Q164-L485 HydrophobicContact CB-CD1 3.68Å; Q164-L485 HydrophobicContact CG-CD1 3.98Å; V340-L485 HydrophobicContact CG2-CB 4.08Å; V340-L485 HydrophobicContact CG2-CD1 4.12Å; H342-L485 HydrophobicContact CB-CB 4.33Å; H342-L485 PolarHBondContact CD2-O 2.97Å; P343-L485 HydrophobicContact CG-CD1 3.7Å; P343-L485 HydrophobicContact CG-CD2 4.45Å; A481-L485 WeakPolarHBondContact O-CB 3.36Å; A481-L485 VanDerWaalsContact O-CG 3.32Å; A481-L485 WeakPolarHBondContact O-CG 3.42Å; A481-L485 PolarHBondContact O-N 3.03Å; A482-L485 PolarHBondContact O-N 3.28Å; T483-L485 VanDerWaalsContact C-N 3.33Å; T483-L485 PolarHBondContact O-N 3.14Å; L485-L489 HydrophobicContact CD2-CD1 4.16Å; L485-P490 WeakPolarHBondContact O-CD 3.37Å; L485-P490 WeakPolarHBondContact O-CG 3.15Å
486	I	96.4	Very high	95.9	Very high	0 Å²	0	18.4 Å²	18.4	0%	0	8%	0.084	C	C	.	.	I	π-helix	trans	-88.6	-44.9	179.1	-64.9	166.5	0	0	0	110.7	S125 A336 V340 A482 F514	S125-I486 WeakPolarHBondContact CB-O 3.42Å; S125-I486 PolarHBondContact OG-O 3.31Å; A336-I486 HydrophobicContact CB-CD1 4.28Å; A336-I486 WeakPolarHBondContact O-CD1 3.25Å; V340-I486 HydrophobicContact CB-CD1 4.02Å; V340-I486 HydrophobicContact CB-CG1 4.32Å; V340-I486 HydrophobicContact CG2-CD1 4.47Å; V340-I486 HydrophobicContact CG2-CG1 4.28Å; A482-I486 HydrophobicContact CB-CD1 4.28Å; A482-I486 VanDerWaalsContact O-CB 3.29Å; A482-I486 WeakPolarHBondContact O-CB 3.47Å; A482-I486 WeakPolarHBondContact O-CG1 3.29Å; A482-I486 PolarHBondContact O-N 3.42Å; I486-F514 VanDerWaalsContact O-CE1 3.27Å; I486-F514 WeakPolarHBondContact O-CE1 3.31Å; I486-F514 WeakPolarHBondContact O-CZ 3.48Å
487	F	96	Very high	95.7	Very high	9 Å²	9	16 Å²	16	4%	0.039	8%	0.075	C	C	.	.	I	π-helix	trans	-104.2	-52.3	-169.7	-59.4	-89.6	0	0	0	112.2	L121 T483 A491 F514 G518 F521	L121-F487 HydrophobicContact CB-CE1 4Å; L121-F487 HydrophobicContact CB-CZ 4.4Å; L121-F487 HydrophobicContact CD1-CE1 3.96Å; L121-F487 HydrophobicContact CD1-CZ 4.33Å; L121-F487 HydrophobicContact CG-CE1 4.37Å; T483-F487 HydrophobicContact CG2-CD2 3.91Å; T483-F487 WeakPolarHBondContact O-CB 3.25Å; T483-F487 PolarHBondContact O-N 3.23Å; F487-A491 WeakPolarHBondContact O-CB 3.41Å; F487-F514 HydrophobicContact CB-CZ 4.39Å; F487-F514 AromaticContact CD1-CD2 3.95Å; F487-F514 HydrophobicContact CD1-CD2 3.95Å; F487-F514 HydrophobicContact CD1-CE1 4.32Å; F487-F514 AromaticContact CD1-CE2 3.25Å; F487-F514 HydrophobicContact CD1-CE2 3.25Å; F487-F514 AromaticContact CD1-CZ 3.47Å; F487-F514 HydrophobicContact CD1-CZ 3.47Å; F487-F514 VanDerWaalsContact CD1-CZ 3.47Å; F487-F514 HydrophobicContact CE1-CD2 4.46Å; F487-F514 AromaticContact CE1-CE2 3.58Å; F487-F514 HydrophobicContact CE1-CE2 3.58Å; F487-F514 AromaticContact CE1-CZ 4Å; F487-F514 HydrophobicContact CE1-CZ 4Å; F487-F514 HydrophobicContact CG-CE2 4.32Å; F487-F514 HydrophobicContact CG-CZ 4.15Å; F487-G518 VanDerWaalsContact CB-CA 3.47Å; F487-F521 HydrophobicContact CE2-CD1 4.38Å
488	I	97.4	Very high	95.3	Very high	18 Å²	18	15.7 Å²	15.7	9%	0.092	7%	0.074	C	C	.	.	I	π-helix	trans	-81.5	-57.3	-162.6	-58.9	175.9	0	0	0	111.7	T483 M484 A491 A492 L515 V519 M522	T483-I488 PolarHBondContact O-N 3.26Å; M484-I488 HydrophobicContact CE-CD1 4.11Å; M484-I488 PolarHBondContact O-N 3.28Å; M484-I488 HydrophobicContact SD-CB 3.65Å; M484-I488 HydrophobicContact SD-CD1 4.01Å; M484-I488 HydrophobicContact SD-CG1 4.4Å; M484-I488 HydrophobicContact SD-CG2 3.55Å; M484-I488 VanDerWaalsContact SD-CG2 3.55Å; I488-A491 PolarHBondContact O-N 3.45Å; I488-A492 WeakPolarHBondContact O-CB 3.41Å; I488-A492 PolarHBondContact O-N 3Å; I488-L515 HydrophobicContact CB-CD1 4.12Å; I488-L515 HydrophobicContact CG1-CD1 4.46Å; I488-L515 HydrophobicContact CG2-CD1 3.67Å; I488-L515 WeakPolarHBondContact O-CD1 3.23Å; I488-V519 HydrophobicContact CD1-CG2 4.06Å; I488-V519 HydrophobicContact CG1-CG2 4.26Å; I488-M522 HydrophobicContact CD1-CB 4.39Å; I488-M522 HydrophobicContact CD1-CE 3.66Å; I488-M522 HydrophobicContact CD1-SD 3.72Å
489	L	96.5	Very high	94.8	Very high	8 Å²	8	24.1 Å²	24.1	4%	0.042	11%	0.11	C	C	.	.	H	α-helix	trans	-65.8	-47.8	-172.5	-65.2	175.4	0	0	0	113.1	Y141 A156 A157 M484 L485 A491 A492 F493	Y141-L489 HydrophobicContact CE1-CB 4.12Å; Y141-L489 HydrophobicContact CE1-CD1 4.01Å; A156-L489 HydrophobicContact CB-CD2 4.08Å; A157-L489 HydrophobicContact CB-CD1 4.34Å; M484-L489 HydrophobicContact CG-CD1 3.79Å; M484-L489 HydrophobicContact CG-CD2 4.42Å; M484-L489 HydrophobicContact CG-CG 3.77Å; M484-L489 WeakPolarHBondContact O-CB 3.41Å; M484-L489 WeakPolarHBondContact O-CG 3.29Å; M484-L489 PolarHBondContact O-N 2.75Å; M484-L489 HydrophobicContact SD-CD1 4.43Å; M484-L489 HydrophobicContact SD-CD2 4Å; M484-L489 HydrophobicContact SD-CG 3.82Å; L485-L489 HydrophobicContact CD2-CD1 4.16Å; L489-A491 VanDerWaalsContact C-N 3.33Å; L489-A491 PolarHBondContact O-N 3.27Å; L489-A492 PolarHBondContact O-N 3Å; L489-F493 HydrophobicContact CB-CE1 4.5Å; L489-F493 HydrophobicContact CB-CE2 4.16Å; L489-F493 HydrophobicContact CB-CZ 4.08Å; L489-F493 HydrophobicContact CD2-CE1 4Å; L489-F493 HydrophobicContact CD2-CZ 3.89Å; L489-F493 HydrophobicContact CG-CZ 4.42Å; L489-F493 VanDerWaalsContact O-CB 3.32Å; L489-F493 WeakPolarHBondContact O-CB 3.41Å; L489-F493 WeakPolarHBondContact O-CD1 3.46Å; L489-F493 WeakPolarHBondContact O-CD2 3.39Å; L489-F493 WeakPolarHBondContact O-CG 3.39Å; L489-F493 PolarHBondContact O-N 3.48Å
490	P	96.6	Very high	93.8	Very high	0 Å²	0	28 Å²	28	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-60.1	-42.3	178.9	-26.6	39	0	0	0	112.5	S125 L128 L129 Y141 L485 Y494	S125-P490 VanDerWaalsContact OG-CG 3.27Å; S125-P490 WeakPolarHBondContact OG-CG 3.47Å; L128-P490 HydrophobicContact CB-CB 4.29Å; L129-P490 HydrophobicContact CB-CB 4.48Å; Y141-P490 WeakPolarHBondContact OH-CG 3.42Å; L485-P490 WeakPolarHBondContact O-CD 3.37Å; L485-P490 WeakPolarHBondContact O-CG 3.15Å; P490-Y494 VanDerWaalsContact O-CB 3.25Å; P490-Y494 WeakPolarHBondContact O-CB 3.34Å; P490-Y494 PolarHBondContact O-N 2.89Å
491	A	96.8	Very high	92.8	Very high	0 Å²	0	29.8 Å²	29.8	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-67.3	-46.7	177.7	0	0	0	0	0	112.4	L128 F487 I488 L489 F493 Y494 L495 F514 L515	L128-A491 HydrophobicContact CD1-CB 4.39Å; F487-A491 WeakPolarHBondContact O-CB 3.41Å; I488-A491 PolarHBondContact O-N 3.45Å; L489-A491 VanDerWaalsContact C-N 3.33Å; L489-A491 PolarHBondContact O-N 3.27Å; A491-F493 PolarHBondContact O-N 3.45Å; A491-Y494 PolarHBondContact O-N 3.49Å; A491-L495 WeakPolarHBondContact O-CG 3.37Å; A491-L495 PolarHBondContact O-N 3.02Å; A491-F514 HydrophobicContact CB-CD1 4.04Å; A491-L515 HydrophobicContact CB-CB 3.82Å; A491-L515 HydrophobicContact CB-CD1 4.46Å
492	A	96.6	Very high	91.9	Very high	15 Å²	15	34.2 Å²	34.2	12%	0.124	17%	0.174	C	C	.	.	H	α-helix	trans	-63	-42	179.2	0	0	0	0	0	111.7	F149 I488 L489 Y494 R496 L515	F149-A492 HydrophobicContact CE2-CB 3.84Å; F149-A492 HydrophobicContact CZ-CB 4.11Å; I488-A492 WeakPolarHBondContact O-CB 3.41Å; I488-A492 PolarHBondContact O-N 3Å; L489-A492 PolarHBondContact O-N 3Å; A492-Y494 VanDerWaalsContact C-N 3.35Å; A492-R496 WeakPolarHBondContact O-CB 3.5Å; A492-R496 PolarHBondContact O-N 3.08Å; A492-L515 HydrophobicContact CB-CD1 4.27Å
493	F	95.8	Very high	90.9	Very high	1 Å²	1	42.2 Å²	42.2	0%	0.004	21%	0.206	C	C	.	.	H	α-helix	trans	-64.7	-40.9	175.3	-64.1	-8.5	0	0	0	111	T132 Y141 L144 A148 F149 A157 L489 A491 R496 L497	T132-F493 VanDerWaalsContact CG2-C 3.46Å; T132-F493 HydrophobicContact CG2-CB 3.95Å; Y141-F493 AromaticContact CD1-CE2 3.9Å; Y141-F493 HydrophobicContact CD1-CE2 3.9Å; Y141-F493 HydrophobicContact CE1-CD2 4.36Å; Y141-F493 AromaticContact CE1-CE2 3.52Å; Y141-F493 HydrophobicContact CE1-CE2 3.52Å; Y141-F493 HydrophobicContact CE1-CZ 4.29Å; L144-F493 HydrophobicContact CB-CD2 4.5Å; L144-F493 HydrophobicContact CD2-CD2 3.82Å; L144-F493 HydrophobicContact CD2-CE2 4.49Å; L144-F493 HydrophobicContact CG-CD2 3.97Å; A148-F493 HydrophobicContact CB-CD1 3.74Å; A148-F493 HydrophobicContact CB-CE1 4.33Å; A148-F493 HydrophobicContact CB-CG 4.35Å; F149-F493 HydrophobicContact CD2-CD1 4.07Å; F149-F493 HydrophobicContact CD2-CE1 4.11Å; F149-F493 AromaticContact CE2-CD1 3.97Å; F149-F493 HydrophobicContact CE2-CD1 3.97Å; F149-F493 HydrophobicContact CE2-CE1 4.37Å; A157-F493 HydrophobicContact CB-CZ 4.41Å; L489-F493 HydrophobicContact CB-CE1 4.5Å; L489-F493 HydrophobicContact CB-CE2 4.16Å; L489-F493 HydrophobicContact CB-CZ 4.08Å; L489-F493 HydrophobicContact CD2-CE1 4Å; L489-F493 HydrophobicContact CD2-CZ 3.89Å; L489-F493 HydrophobicContact CG-CZ 4.42Å; L489-F493 VanDerWaalsContact O-CB 3.32Å; L489-F493 WeakPolarHBondContact O-CB 3.41Å; L489-F493 WeakPolarHBondContact O-CD1 3.46Å; L489-F493 WeakPolarHBondContact O-CD2 3.39Å; L489-F493 WeakPolarHBondContact O-CG 3.39Å; L489-F493 PolarHBondContact O-N 3.48Å; A491-F493 PolarHBondContact O-N 3.45Å; F493-R496 PolarHBondContact O-N 3.48Å; F493-L497 HydrophobicContact CB-CD1 4.44Å; F493-L497 VanDerWaalsContact O-CB 3.3Å; F493-L497 WeakPolarHBondContact O-CB 3.19Å; F493-L497 PolarHBondContact O-N 3.28Å
494	Y	95.1	Very high	90.1	Very high	7 Å²	7	49.2 Å²	49.2	3%	0.027	24%	0.243	C	C	.	.	H	α-helix	trans	-62.3	-50.2	179.1	-178.8	-92.2	0	0	0	112.2	L128 M131 T132 P490 A491 A492 R496 V498 L501 Q507 K508 A511	L128-Y494 HydrophobicContact CB-CD2 4.46Å; L128-Y494 HydrophobicContact CD2-CD1 3.99Å; L128-Y494 HydrophobicContact CD2-CD2 3.68Å; L128-Y494 HydrophobicContact CD2-CE1 4.24Å; L128-Y494 HydrophobicContact CD2-CE2 3.96Å; L128-Y494 HydrophobicContact CD2-CG 3.71Å; M131-Y494 HydrophobicContact CB-CD2 4.15Å; M131-Y494 HydrophobicContact CB-CE2 4.04Å; T132-Y494 HydrophobicContact CG2-CD2 4.2Å; T132-Y494 HydrophobicContact CG2-CG 4.42Å; P490-Y494 VanDerWaalsContact O-CB 3.25Å; P490-Y494 WeakPolarHBondContact O-CB 3.34Å; P490-Y494 PolarHBondContact O-N 2.89Å; A491-Y494 PolarHBondContact O-N 3.49Å; A492-Y494 VanDerWaalsContact C-N 3.35Å; Y494-R496 PolarHBondContact O-N 3.01Å; Y494-V498 HydrophobicContact CD2-CB 4.24Å; Y494-V498 HydrophobicContact CD2-CG2 3.53Å; Y494-V498 HydrophobicContact CE2-CB 4.13Å; Y494-V498 HydrophobicContact CE2-CG1 4.14Å; Y494-V498 HydrophobicContact CE2-CG2 3.72Å; Y494-V498 HydrophobicContact CG-CG2 4.14Å; Y494-V498 VanDerWaalsContact O-CB 3.29Å; Y494-V498 WeakPolarHBondContact O-CB 3.35Å; Y494-V498 WeakPolarHBondContact O-CG2 3.25Å; Y494-V498 PolarHBondContact O-N 3.44Å; Y494-V498 VanDerWaalsContact O-N 3.09Å; Y494-L501 VanDerWaalsContact OH-CD1 3.29Å; Y494-L501 WeakPolarHBondContact OH-CD1 3.29Å; Y494-Q507 PolarHBondContact OH-OE1 3.21Å; Y494-K508 HydrophobicContact CE1-CG 4.18Å; Y494-A511 HydrophobicContact CD1-CB 3.73Å; Y494-A511 HydrophobicContact CE1-CB 4.19Å
495	L	94.1	Very high	89.6	Confident	38 Å²	38	48.7 Å²	48.7	20%	0.199	24%	0.243	C	C	.	.	H	α-helix	trans	-59.7	-31.2	178.8	-69.1	170.4	0	0	0	112.7	A491 K508 A511 A512 L515	A491-L495 WeakPolarHBondContact O-CG 3.37Å; A491-L495 PolarHBondContact O-N 3.02Å; L495-K508 HydrophobicContact CD2-CB 4.13Å; L495-K508 HydrophobicContact CD2-CG 4.29Å; L495-K508 WeakPolarHBondContact CD2-O 3.48Å; L495-A511 HydrophobicContact CD2-CB 4Å; L495-A511 HydrophobicContact CG-CB 4.18Å; L495-A512 HydrophobicContact CD1-CB 4.16Å; L495-A512 HydrophobicContact CD2-CB 4.41Å; L495-L515 HydrophobicContact CD1-CD2 4.02Å
496	R	92.2	Very high	89.2	Confident	149 Å²	149	58.4 Å²	58.4	56%	0.562	28%	0.28	S	S	*	.	H	α-helix	trans	-90.8	-42.3	-174.4	-171	59.3	172.4	-172.2	1.6	114	A148 F149 A492 F493 Y494	A148-R496 HydrophobicContact CB-CB 4.39Å; A148-R496 HydrophobicContact CB-CG 4.24Å; A148-R496 WeakPolarHBondContact O-CG 3.38Å; A148-R496 PolarHBondContact O-NE 3.49Å; F149-R496 HydrophobicContact CE1-CB 4.41Å; F149-R496 HydrophobicContact CE1-CG 4.11Å; F149-R496 HydrophobicContact CE2-CB 4.29Å; F149-R496 HydrophobicContact CZ-CB 3.92Å; F149-R496 HydrophobicContact CZ-CG 4.1Å; A492-R496 WeakPolarHBondContact O-CB 3.5Å; A492-R496 PolarHBondContact O-N 3.08Å; F493-R496 PolarHBondContact O-N 3.48Å; Y494-R496 PolarHBondContact O-N 3.01Å
497	L	90.4	Very high	88.8	Confident	30 Å²	30	63 Å²	63	16%	0.157	30%	0.301	C	S	.	.	H	α-helix	trans	-90	-33.1	-173.6	-67.6	175.9	0	0	0	112.8	L144 K147 A148 F493 K499	L144-L497 HydrophobicContact CD1-CD1 3.3Å; L144-L497 HydrophobicContact CG-CD1 3.84Å; K147-L497 HydrophobicContact CB-CD2 4.17Å; A148-L497 HydrophobicContact CB-CD1 3.98Å; A148-L497 HydrophobicContact CB-CD2 4.14Å; A148-L497 HydrophobicContact CB-CG 3.85Å; F493-L497 HydrophobicContact CB-CD1 4.44Å; F493-L497 VanDerWaalsContact O-CB 3.3Å; F493-L497 WeakPolarHBondContact O-CB 3.19Å; F493-L497 PolarHBondContact O-N 3.28Å; L497-K499 PolarHBondContact O-N 3.39Å; L497-K499 VanDerWaalsContact O-N 3.09Å
498	V	88.3	Confident	88.5	Confident	5 Å²	5	62.9 Å²	62.9	3%	0.03	30%	0.301	C	S	.	.			trans	-83.5	93.6	-177.6	-174.1	0	0	0	0	109.6	T132 E135 Y494 S500 L501 K508	T132-V498 HydrophobicContact CG2-CG2 4.23Å; E135-V498 HydrophobicContact CB-CG2 4.34Å; E135-V498 HydrophobicContact CG-CG1 4.4Å; E135-V498 HydrophobicContact CG-CG2 4.07Å; Y494-V498 HydrophobicContact CD2-CB 4.24Å; Y494-V498 HydrophobicContact CD2-CG2 3.53Å; Y494-V498 HydrophobicContact CE2-CB 4.13Å; Y494-V498 HydrophobicContact CE2-CG1 4.14Å; Y494-V498 HydrophobicContact CE2-CG2 3.72Å; Y494-V498 HydrophobicContact CG-CG2 4.14Å; Y494-V498 VanDerWaalsContact O-CB 3.29Å; Y494-V498 WeakPolarHBondContact O-CB 3.35Å; Y494-V498 WeakPolarHBondContact O-CG2 3.25Å; Y494-V498 PolarHBondContact O-N 3.44Å; Y494-V498 VanDerWaalsContact O-N 3.09Å; V498-S500 WeakPolarHBondContact CG1-OG 3.25Å; V498-L501 HydrophobicContact CG1-CD1 4.32Å; V498-K508 WeakPolarHBondContact O-CE 3.11Å; V498-K508 PolarHBondContact O-NZ 3.47Å
499	K	83.3	Confident	88.2	Confident	177 Å²	177	65.7 Å²	65.7	77%	0.77	32%	0.315	S	S	*	.			trans	-90.2	-12.9	178.9	-65.3	-176.4	-176.8	177.7	0	113.9	L497 L501	L497-K499 PolarHBondContact O-N 3.39Å; L497-K499 VanDerWaalsContact O-N 3.09Å; K499-L501 PolarHBondContact O-N 3.39Å
500	S	74.9	Confident	88.1	Confident	82 Å²	82	66.9 Å²	66.9	57%	0.573	33%	0.325	S	S	*	.	S	Bend	trans	-62.5	-21.3	-177	52	0	0	0	0	114.3	V498	V498-S500 WeakPolarHBondContact CG1-OG 3.25Å
501	L	77.1	Confident	87.9	Confident	48 Å²	48	66.9 Å²	66.9	25%	0.251	33%	0.325	S	S	.	.	S	Bend	trans	-110.8	138.9	-178.3	-68.6	155.1	0	0	0	111.9	Y494 V498 K499 K508	Y494-L501 VanDerWaalsContact OH-CD1 3.29Å; Y494-L501 WeakPolarHBondContact OH-CD1 3.29Å; V498-L501 HydrophobicContact CG1-CD1 4.32Å; K499-L501 PolarHBondContact O-N 3.39Å; L501-K508 VanDerWaalsContact O-CE 3.3Å; L501-K508 WeakPolarHBondContact O-CE 3.3Å; L501-K508 PolarHBondContact O-NZ 3.25Å
502	P	77.8	Confident	87.9	Confident	92 Å²	92	69 Å²	69	60%	0.597	34%	0.342	S	S	*	.			trans	-63.7	150.6	173.4	27.1	-33.5	0	0	0	111	N504 S505	P502-N504 PolarHBondContact O-N 3.44Å; P502-S505 VanDerWaalsContact O-CB 3.27Å; P502-S505 WeakPolarHBondContact O-CB 3.15Å; P502-S505 PolarHBondContact O-N 2.9Å
503	Y	74.3	Confident	87.8	Confident	169 Å²	169	72.3 Å²	72.3	66%	0.663	36%	0.36	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.3	-27.4	-177.2	-74.1	-79.3	0	0	0	113.9	S505 K508	Y503-S505 VanDerWaalsContact C-N 3.26Å; Y503-S505 PolarHBondContact O-N 2.94Å; Y503-K508 HydrophobicContact CD1-CD 4.16Å
504	N	78.2	Confident	87.8	Confident	147 Å²	147	72.9 Å²	72.9	79%	0.786	36%	0.363	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.2	1.3	176.4	-74.9	14.3	0	0	0	114	P502	P502-N504 PolarHBondContact O-N 3.44Å
505	S	88.1	Confident	87.9	Confident	27 Å²	27	74.5 Å²	74.5	19%	0.189	37%	0.372	C	S	.	.	S	Bend	trans	-63.9	138.4	175	176.5	0	0	0	0	110.4	P502 Y503 Q507 K508 I509	P502-S505 VanDerWaalsContact O-CB 3.27Å; P502-S505 WeakPolarHBondContact O-CB 3.15Å; P502-S505 PolarHBondContact O-N 2.9Å; Y503-S505 VanDerWaalsContact C-N 3.26Å; Y503-S505 PolarHBondContact O-N 2.94Å; S505-Q507 PolarHBondContact O-N 2.89Å; S505-Q507 PolarHBondContact OG-N 3.09Å; S505-K508 PolarHBondContact O-N 3.36Å; S505-I509 PolarHBondContact O-N 3.43Å
506	W	86.9	Confident	88.1	Confident	205 Å²	205	75.3 Å²	75.3	78%	0.777	38%	0.384	S	S	*	.	H	α-helix	trans	-50.3	-34.3	175.1	-176.8	-105.3	0	0	0	112.6	I509 S510	W506-I509 PolarHBondContact O-N 3.03Å; W506-S510 WeakPolarHBondContact O-CB 3.36Å; W506-S510 PolarHBondContact O-N 3.38Å; W506-S510 PolarHBondContact O-OG 3.29Å
507	Q	87.9	Confident	88.2	Confident	95 Å²	95	71.9 Å²	71.9	44%	0.444	38%	0.379	S	S	.	.	H	α-helix	trans	-67.1	-36.4	177.9	-65	-179.7	-13.9	0	0	113.5	Y494 S505 S510 A511	Y494-Q507 PolarHBondContact OH-OE1 3.21Å; S505-Q507 PolarHBondContact O-N 2.89Å; S505-Q507 PolarHBondContact OG-N 3.09Å; Q507-S510 VanDerWaalsContact CA-OG 3.32Å; Q507-S510 WeakPolarHBondContact CA-OG 3.25Å; Q507-S510 PolarHBondContact O-OG 2.96Å; Q507-A511 WeakPolarHBondContact O-CB 3.38Å; Q507-A511 PolarHBondContact O-N 2.79Å; Q507-A511 VanDerWaalsContact O-N 3.15Å
508	K	89.8	Confident	88.4	Confident	7 Å²	7	70.5 Å²	70.5	3%	0.03	37%	0.372	C	S	.	.	H	α-helix	trans	-77.3	-37.5	174.9	-77.4	-169.1	168.5	179.3	0	112	Y494 L495 V498 L501 Y503 S505 A511 A512	Y494-K508 HydrophobicContact CE1-CG 4.18Å; L495-K508 HydrophobicContact CD2-CB 4.13Å; L495-K508 HydrophobicContact CD2-CG 4.29Å; L495-K508 WeakPolarHBondContact CD2-O 3.48Å; V498-K508 WeakPolarHBondContact O-CE 3.11Å; V498-K508 PolarHBondContact O-NZ 3.47Å; L501-K508 VanDerWaalsContact O-CE 3.3Å; L501-K508 WeakPolarHBondContact O-CE 3.3Å; L501-K508 PolarHBondContact O-NZ 3.25Å; Y503-K508 HydrophobicContact CD1-CD 4.16Å; S505-K508 PolarHBondContact O-N 3.36Å; K508-A511 PolarHBondContact O-N 3.03Å; K508-A512 WeakPolarHBondContact O-CB 3.29Å; K508-A512 PolarHBondContact O-N 3.47Å
509	I	92.1	Very high	88.8	Confident	77 Å²	77	72.8 Å²	72.8	40%	0.395	39%	0.386	S	S	.	.	H	α-helix	trans	-62.5	-48.7	175.4	-64	171.6	0	0	0	110	S505 W506 A511 A512 V513	S505-I509 PolarHBondContact O-N 3.43Å; W506-I509 PolarHBondContact O-N 3.03Å; I509-A511 PolarHBondContact O-N 3.41Å; I509-A512 PolarHBondContact O-N 3.4Å; I509-A512 VanDerWaalsContact O-N 3.15Å; I509-V513 WeakPolarHBondContact O-CG2 3.23Å; I509-V513 PolarHBondContact O-N 3Å
510	S	93	Very high	89.4	Confident	34 Å²	34	69.4 Å²	69.4	24%	0.238	38%	0.38	C	S	.	.	H	α-helix	trans	-58	-44.2	175	50.3	0	0	0	0	112.6	Y124 W506 Q507 A512 V513 F514	Y124-S510 PolarHBondContact OH-OG 3.05Å; Y124-S510 VanDerWaalsContact OH-OG 3.06Å; W506-S510 WeakPolarHBondContact O-CB 3.36Å; W506-S510 PolarHBondContact O-N 3.38Å; W506-S510 PolarHBondContact O-OG 3.29Å; Q507-S510 VanDerWaalsContact CA-OG 3.32Å; Q507-S510 WeakPolarHBondContact CA-OG 3.25Å; Q507-S510 PolarHBondContact O-OG 2.96Å; S510-A512 VanDerWaalsContact C-N 3.33Å; S510-A512 PolarHBondContact O-N 3.24Å; S510-V513 PolarHBondContact O-N 3.45Å; S510-F514 VanDerWaalsContact O-CB 3.25Å; S510-F514 WeakPolarHBondContact O-CB 3.39Å; S510-F514 PolarHBondContact O-N 3.25Å
511	A	94.4	Very high	90.3	Very high	0 Å²	0	67.5 Å²	67.5	0%	0	36%	0.361	C	S	.	.	H	α-helix	trans	-63	-37.6	175.5	0	0	0	0	0	112.5	Y124 L128 Y494 L495 Q507 K508 I509 F514 L515	Y124-A511 PolarHBondContact OH-N 3.47Å; L128-A511 HydrophobicContact CD1-CB 4.34Å; Y494-A511 HydrophobicContact CD1-CB 3.73Å; Y494-A511 HydrophobicContact CE1-CB 4.19Å; L495-A511 HydrophobicContact CD2-CB 4Å; L495-A511 HydrophobicContact CG-CB 4.18Å; Q507-A511 WeakPolarHBondContact O-CB 3.38Å; Q507-A511 PolarHBondContact O-N 2.79Å; Q507-A511 VanDerWaalsContact O-N 3.15Å; K508-A511 PolarHBondContact O-N 3.03Å; I509-A511 PolarHBondContact O-N 3.41Å; A511-F514 PolarHBondContact O-N 3.32Å; A511-L515 WeakPolarHBondContact O-CB 3.45Å; A511-L515 PolarHBondContact O-N 2.98Å
512	A	95.3	Very high	91.2	Very high	43 Å²	43	67 Å²	67	36%	0.355	36%	0.358	S	S	.	.	H	α-helix	trans	-67.9	-41.5	176.2	0	0	0	0	0	112.6	L495 K508 I509 S510 L515 A516	L495-A512 HydrophobicContact CD1-CB 4.16Å; L495-A512 HydrophobicContact CD2-CB 4.41Å; K508-A512 WeakPolarHBondContact O-CB 3.29Å; K508-A512 PolarHBondContact O-N 3.47Å; I509-A512 PolarHBondContact O-N 3.4Å; I509-A512 VanDerWaalsContact O-N 3.15Å; S510-A512 VanDerWaalsContact C-N 3.33Å; S510-A512 PolarHBondContact O-N 3.24Å; A512-L515 PolarHBondContact O-N 3.07Å; A512-A516 PolarHBondContact O-N 3.11Å
513	V	95.4	Very high	92	Very high	86 Å²	86	67.3 Å²	67.3	52%	0.521	35%	0.354	S	S	.	.	H	α-helix	trans	-63	-44.7	173	172.9	0	0	0	0	110.4	I509 S510 L515 A516 V517	I509-V513 WeakPolarHBondContact O-CG2 3.23Å; I509-V513 PolarHBondContact O-N 3Å; S510-V513 PolarHBondContact O-N 3.45Å; V513-L515 VanDerWaalsContact C-N 3.33Å; V513-L515 PolarHBondContact O-N 3.39Å; V513-A516 PolarHBondContact O-N 2.92Å; V513-V517 HydrophobicContact CG1-CG2 4.29Å; V513-V517 WeakPolarHBondContact O-CG2 3.14Å; V513-V517 PolarHBondContact O-N 3.33Å
514	F	95.9	Very high	92.9	Very high	12 Å²	12	60.9 Å²	60.9	5%	0.053	34%	0.339	C	S	.	.	H	α-helix	trans	-60	-42	178.2	-172.2	-120.6	0	0	0	112.1	L121 Y124 L128 I486 F487 A491 S510 A511 G518	L121-F514 HydrophobicContact CB-CE2 3.93Å; L121-F514 HydrophobicContact CB-CZ 4.42Å; L121-F514 HydrophobicContact CD2-CD2 3.94Å; L121-F514 HydrophobicContact CD2-CE2 3.56Å; L121-F514 HydrophobicContact CG-CE2 4.27Å; Y124-F514 AromaticContact CD1-CD1 3.96Å; Y124-F514 HydrophobicContact CD1-CD1 3.96Å; Y124-F514 HydrophobicContact CD1-CD2 4.24Å; Y124-F514 HydrophobicContact CD1-CE1 4.09Å; Y124-F514 HydrophobicContact CD1-CE2 4.35Å; Y124-F514 HydrophobicContact CD1-CG 4.06Å; Y124-F514 HydrophobicContact CD1-CZ 4.28Å; Y124-F514 HydrophobicContact CE1-CB 4.08Å; Y124-F514 AromaticContact CE1-CD1 3.86Å; Y124-F514 HydrophobicContact CE1-CD1 3.86Å; Y124-F514 HydrophobicContact CE1-CD2 4.44Å; Y124-F514 HydrophobicContact CE1-CE1 4.42Å; Y124-F514 AromaticContact CE1-CG 3.89Å; Y124-F514 HydrophobicContact CE1-CG 3.89Å; L128-F514 HydrophobicContact CD1-CD1 4.14Å; L128-F514 HydrophobicContact CD1-CE1 4.5Å; I486-F514 VanDerWaalsContact O-CE1 3.27Å; I486-F514 WeakPolarHBondContact O-CE1 3.31Å; I486-F514 WeakPolarHBondContact O-CZ 3.48Å; F487-F514 HydrophobicContact CB-CZ 4.39Å; F487-F514 AromaticContact CD1-CD2 3.95Å; F487-F514 HydrophobicContact CD1-CD2 3.95Å; F487-F514 HydrophobicContact CD1-CE1 4.32Å; F487-F514 AromaticContact CD1-CE2 3.25Å; F487-F514 HydrophobicContact CD1-CE2 3.25Å; F487-F514 AromaticContact CD1-CZ 3.47Å; F487-F514 HydrophobicContact CD1-CZ 3.47Å; F487-F514 VanDerWaalsContact CD1-CZ 3.47Å; F487-F514 HydrophobicContact CE1-CD2 4.46Å; F487-F514 AromaticContact CE1-CE2 3.58Å; F487-F514 HydrophobicContact CE1-CE2 3.58Å; F487-F514 AromaticContact CE1-CZ 4Å; F487-F514 HydrophobicContact CE1-CZ 4Å; F487-F514 HydrophobicContact CG-CE2 4.32Å; F487-F514 HydrophobicContact CG-CZ 4.15Å; A491-F514 HydrophobicContact CB-CD1 4.04Å; S510-F514 VanDerWaalsContact O-CB 3.25Å; S510-F514 WeakPolarHBondContact O-CB 3.39Å; S510-F514 PolarHBondContact O-N 3.25Å; A511-F514 PolarHBondContact O-N 3.32Å; F514-G518 PolarHBondContact O-N 3.29Å
515	L	97.1	Very high	93.6	Very high	42 Å²	42	54.3 Å²	54.3	22%	0.22	30%	0.304	C	S	.	.	H	α-helix	trans	-60.3	-48.7	172.2	177.2	61.7	0	0	0	112.1	I488 A491 A492 L495 A511 A512 V513 G518 V519	I488-L515 HydrophobicContact CB-CD1 4.12Å; I488-L515 HydrophobicContact CG1-CD1 4.46Å; I488-L515 HydrophobicContact CG2-CD1 3.67Å; I488-L515 WeakPolarHBondContact O-CD1 3.23Å; A491-L515 HydrophobicContact CB-CB 3.82Å; A491-L515 HydrophobicContact CB-CD1 4.46Å; A492-L515 HydrophobicContact CB-CD1 4.27Å; L495-L515 HydrophobicContact CD1-CD2 4.02Å; A511-L515 WeakPolarHBondContact O-CB 3.45Å; A511-L515 PolarHBondContact O-N 2.98Å; A512-L515 PolarHBondContact O-N 3.07Å; V513-L515 VanDerWaalsContact C-N 3.33Å; V513-L515 PolarHBondContact O-N 3.39Å; L515-G518 PolarHBondContact O-N 3.25Å; L515-V519 WeakPolarHBondContact O-CG2 3.45Å; L515-V519 PolarHBondContact O-N 2.65Å
516	A	96.8	Very high	93.8	Very high	54 Å²	54	55 Å²	55	45%	0.446	31%	0.306	S	S	.	.	H	α-helix	trans	-62.7	-44.9	-178.8	0	0	0	0	0	112	A512 V513 G518 V519 V520	A512-A516 PolarHBondContact O-N 3.11Å; V513-A516 PolarHBondContact O-N 2.92Å; A516-G518 VanDerWaalsContact C-N 3.3Å; A516-G518 PolarHBondContact O-N 3.4Å; A516-V519 PolarHBondContact O-N 2.03Å; A516-V520 WeakPolarHBondContact O-CG2 3.44Å; A516-V520 PolarHBondContact O-N 3.21Å
517	V	94.6	Very high	94.1	Very high	78 Å²	78	48 Å²	48	47%	0.473	29%	0.288	S	S	.	.	H	α-helix	trans	-59	-43.3	174.2	170.9	0	0	0	0	110.6	V513 V519 V520 F521	V513-V517 HydrophobicContact CG1-CG2 4.29Å; V513-V517 WeakPolarHBondContact O-CG2 3.14Å; V513-V517 PolarHBondContact O-N 3.33Å; V517-V519 PolarHBondContact O-N 3.27Å; V517-V520 PolarHBondContact O-N 3.16Å; V517-F521 VanDerWaalsContact O-CB 3.23Å; V517-F521 WeakPolarHBondContact O-CB 3.38Å; V517-F521 PolarHBondContact O-N 2.96Å
518	G	95.6	Very high	94.3	Very high	0 Å²	0	47.9 Å²	47.9	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-58.6	-43.5	176.1	0	0	0	0	0	113.8	T483 F487 F514 L515 A516 F521 M522	T483-G518 WeakPolarHBondContact CG2-O 3.39Å; F487-G518 VanDerWaalsContact CB-CA 3.47Å; F514-G518 PolarHBondContact O-N 3.29Å; L515-G518 PolarHBondContact O-N 3.25Å; A516-G518 VanDerWaalsContact C-N 3.3Å; A516-G518 PolarHBondContact O-N 3.4Å; G518-F521 PolarHBondContact O-N 3.46Å; G518-M522 WeakPolarHBondContact O-CB 3.3Å; G518-M522 PolarHBondContact O-N 3.45Å
519	V	96.8	Very high	94.3	Very high	54 Å²	54	47.5 Å²	47.5	33%	0.327	29%	0.288	S	S	.	.	H	α-helix	trans	-66.1	-45.6	178.1	172.9	0	0	0	0	111.3	I488 L515 A516 V517 F521 M522 I523	I488-V519 HydrophobicContact CD1-CG2 4.06Å; I488-V519 HydrophobicContact CG1-CG2 4.26Å; L515-V519 WeakPolarHBondContact O-CG2 3.45Å; L515-V519 PolarHBondContact O-N 2.65Å; A516-V519 PolarHBondContact O-N 2.03Å; V517-V519 PolarHBondContact O-N 3.27Å; V519-F521 VanDerWaalsContact C-N 3.32Å; V519-F521 PolarHBondContact O-N 3.45Å; V519-M522 PolarHBondContact O-N 3.48Å; V519-I523 HydrophobicContact CG1-CD1 3.77Å; V519-I523 WeakPolarHBondContact O-CG1 3.31Å; V519-I523 PolarHBondContact O-N 3.19Å
520	V	95.6	Very high	94.2	Very high	106 Å²	106	47 Å²	47	64%	0.642	29%	0.289	S	S	*	.	H	α-helix	trans	-61.1	-44.1	176.4	173.1	0	0	0	0	110.5	A516 V517 I523 G524	A516-V520 WeakPolarHBondContact O-CG2 3.44Å; A516-V520 PolarHBondContact O-N 3.21Å; V517-V520 PolarHBondContact O-N 3.16Å; V520-I523 PolarHBondContact O-N 3.3Å; V520-G524 PolarHBondContact O-N 2.61Å
521	F	93.7	Very high	94	Very high	41 Å²	41	49.4 Å²	49.4	18%	0.18	30%	0.298	C	S	.	.	H	α-helix	trans	-62.8	-44.9	178.8	179.6	-110.5	0	0	0	112.4	V332 P333 A336 T483 F487 V517 G518 V519 S525	V332-F521 HydrophobicContact CB-CE2 3.59Å; V332-F521 HydrophobicContact CB-CZ 3.71Å; V332-F521 HydrophobicContact CG1-CD2 4.26Å; V332-F521 HydrophobicContact CG1-CE1 4.34Å; V332-F521 HydrophobicContact CG1-CE2 3.23Å; V332-F521 HydrophobicContact CG1-CZ 3.3Å; P333-F521 HydrophobicContact CG-CZ 4.33Å; A336-F521 HydrophobicContact CB-CE1 4.46Å; T483-F521 HydrophobicContact CG2-CD1 3.63Å; T483-F521 HydrophobicContact CG2-CE1 4.3Å; T483-F521 WeakPolarHBondContact OG1-CD1 3.44Å; T483-F521 WeakPolarHBondContact OG1-CE1 3.35Å; F487-F521 HydrophobicContact CE2-CD1 4.38Å; V517-F521 VanDerWaalsContact O-CB 3.23Å; V517-F521 WeakPolarHBondContact O-CB 3.38Å; V517-F521 PolarHBondContact O-N 2.96Å; G518-F521 PolarHBondContact O-N 3.46Å; V519-F521 VanDerWaalsContact C-N 3.32Å; V519-F521 PolarHBondContact O-N 3.45Å; F521-S525 WeakPolarHBondContact CD2-OG 3.39Å; F521-S525 WeakPolarHBondContact CE2-OG 3.23Å; F521-S525 WeakPolarHBondContact CZ-OG 3.05Å; F521-S525 WeakPolarHBondContact O-CB 3.2Å; F521-S525 PolarHBondContact O-N 2.94Å; F521-S525 PolarHBondContact O-OG 3.15Å
522	M	95.3	Very high	93.6	Very high	39 Å²	39	50.2 Å²	50.2	19%	0.192	30%	0.303	C	S	.	.	H	α-helix	trans	-60.3	-51	177.4	-174.9	173.5	66.7	0	0	111.3	A479 T483 M484 I488 G518 V519 L526	A479-M522 WeakPolarHBondContact O-CG 3.36Å; T483-M522 HydrophobicContact CG2-CB 3.7Å; T483-M522 HydrophobicContact CG2-CG 4.4Å; M484-M522 HydrophobicContact CE-CE 4.21Å; M484-M522 HydrophobicContact CE-SD 3.91Å; I488-M522 HydrophobicContact CD1-CB 4.39Å; I488-M522 HydrophobicContact CD1-CE 3.66Å; I488-M522 HydrophobicContact CD1-SD 3.72Å; G518-M522 WeakPolarHBondContact O-CB 3.3Å; G518-M522 PolarHBondContact O-N 3.45Å; V519-M522 PolarHBondContact O-N 3.48Å; M522-L526 HydrophobicContact CG-CD1 3.91Å; M522-L526 VanDerWaalsContact O-CB 3.31Å; M522-L526 WeakPolarHBondContact O-CB 3.04Å; M522-L526 WeakPolarHBondContact O-CG 3.04Å; M522-L526 PolarHBondContact O-N 3.36Å
523	I	95.2	Very high	93.2	Very high	98 Å²	98	52.2 Å²	52.2	50%	0.503	30%	0.301	S	S	.	.	H	α-helix	trans	-65.3	-46.7	-178.2	-65.1	169.3	0	0	0	110.4	V519 V520 S527	V519-I523 HydrophobicContact CG1-CD1 3.77Å; V519-I523 WeakPolarHBondContact O-CG1 3.31Å; V519-I523 PolarHBondContact O-N 3.19Å; V520-I523 PolarHBondContact O-N 3.3Å; I523-S527 VanDerWaalsContact O-CB 3.27Å; I523-S527 WeakPolarHBondContact O-CB 3.02Å; I523-S527 PolarHBondContact O-N 2.99Å; I523-S527 PolarHBondContact O-OG 3.38Å
524	G	93.5	Very high	92.8	Very high	33 Å²	33	53.5 Å²	53.5	34%	0.34	30%	0.304	S	S	.	.	H	α-helix	trans	-61.4	-50.5	-180	0	0	0	0	0	112.1	V520 S527 L528	V520-G524 PolarHBondContact O-N 2.61Å; G524-S527 PolarHBondContact O-N 3.48Å; G524-L528 WeakPolarHBondContact O-CG 3.38Å; G524-L528 PolarHBondContact O-N 2.93Å
525	S	92.8	Very high	92.3	Very high	9 Å²	9	59.3 Å²	59.3	6%	0.063	33%	0.331	C	S	.	.	H	α-helix	trans	-65.7	-43.9	-177.8	-56.5	0	0	0	0	112.3	F521 S527 L528 I529	F521-S525 WeakPolarHBondContact CD2-OG 3.39Å; F521-S525 WeakPolarHBondContact CE2-OG 3.23Å; F521-S525 WeakPolarHBondContact CZ-OG 3.05Å; F521-S525 WeakPolarHBondContact O-CB 3.2Å; F521-S525 PolarHBondContact O-N 2.94Å; F521-S525 PolarHBondContact O-OG 3.15Å; S525-S527 VanDerWaalsContact C-N 3.34Å; S525-S527 PolarHBondContact O-N 3.48Å; S525-L528 PolarHBondContact O-N 2.96Å; S525-I529 VanDerWaalsContact O-CG1 3.29Å; S525-I529 WeakPolarHBondContact O-CG1 3.36Å; S525-I529 PolarHBondContact O-N 3.38Å
526	L	93.1	Very high	91.5	Very high	43 Å²	43	62.5 Å²	62.5	23%	0.225	35%	0.345	C	S	.	.	H	α-helix	trans	-64.2	-40	176.5	-74.5	172.4	0	0	0	111.8	F476 A479 M522 L528 I529 V530	F476-L526 HydrophobicContact CD2-CD2 4.15Å; F476-L526 HydrophobicContact CE2-CD2 4.24Å; A479-L526 HydrophobicContact CB-CD2 3.83Å; A479-L526 HydrophobicContact CB-CG 3.99Å; M522-L526 HydrophobicContact CG-CD1 3.91Å; M522-L526 VanDerWaalsContact O-CB 3.31Å; M522-L526 WeakPolarHBondContact O-CB 3.04Å; M522-L526 WeakPolarHBondContact O-CG 3.04Å; M522-L526 PolarHBondContact O-N 3.36Å; L526-L528 PolarHBondContact O-N 2.94Å; L526-I529 PolarHBondContact O-N 2.98Å; L526-V530 WeakPolarHBondContact O-CB 3.18Å; L526-V530 VanDerWaalsContact O-CG2 3.24Å; L526-V530 WeakPolarHBondContact O-CG2 3.48Å; L526-V530 PolarHBondContact O-N 3.06Å
527	S	93	Very high	90.3	Very high	58 Å²	58	62.9 Å²	62.9	41%	0.406	34%	0.342	S	S	.	.	H	α-helix	trans	-62.3	-43.8	177	-57.7	0	0	0	0	111.3	I523 G524 S525 V530 L531	I523-S527 VanDerWaalsContact O-CB 3.27Å; I523-S527 WeakPolarHBondContact O-CB 3.02Å; I523-S527 PolarHBondContact O-N 2.99Å; I523-S527 PolarHBondContact O-OG 3.38Å; G524-S527 PolarHBondContact O-N 3.48Å; S525-S527 VanDerWaalsContact C-N 3.34Å; S525-S527 PolarHBondContact O-N 3.48Å; S527-V530 PolarHBondContact O-N 3.36Å; S527-L531 WeakPolarHBondContact O-CB 3.35Å; S527-L531 WeakPolarHBondContact O-CG 3.43Å; S527-L531 PolarHBondContact O-N 3.46Å
528	L	91.4	Very high	88.5	Confident	91 Å²	91	63.4 Å²	63.4	48%	0.476	35%	0.347	S	S	.	.	H	α-helix	trans	-64.6	-42.5	178.1	-69.4	174	0	0	0	112.5	A329 G524 S525 L526 L531 D532	A329-L528 HydrophobicContact CB-CB 4.04Å; A329-L528 HydrophobicContact CB-CD1 4.08Å; G524-L528 WeakPolarHBondContact O-CG 3.38Å; G524-L528 PolarHBondContact O-N 2.93Å; S525-L528 PolarHBondContact O-N 2.96Å; L526-L528 PolarHBondContact O-N 2.94Å; L528-L531 PolarHBondContact O-N 3.06Å; L528-D532 PolarHBondContact O-N 3.35Å
529	I	90	Very high	86.5	Confident	0 Å²	0	66.2 Å²	66.2	0%	0	38%	0.376	C	S	.	.	H	α-helix	trans	-64.7	-44.1	177.6	-68.5	166.2	0	0	0	110.9	Y330 P333 G475 A479 S525 L526 L531 D532 W533	Y330-I529 HydrophobicContact CD1-CG1 4.28Å; Y330-I529 HydrophobicContact CE1-CB 4.48Å; Y330-I529 HydrophobicContact CE1-CD1 4.46Å; Y330-I529 HydrophobicContact CE1-CG1 3.86Å; Y330-I529 HydrophobicContact CE1-CG2 4.1Å; P333-I529 HydrophobicContact CG-CD1 4.31Å; G475-I529 VanDerWaalsContact C-CD1 3.48Å; G475-I529 VanDerWaalsContact O-CD1 3.3Å; G475-I529 WeakPolarHBondContact O-CD1 3.37Å; A479-I529 HydrophobicContact CB-CD1 3.67Å; S525-I529 VanDerWaalsContact O-CG1 3.29Å; S525-I529 WeakPolarHBondContact O-CG1 3.36Å; S525-I529 PolarHBondContact O-N 3.38Å; L526-I529 PolarHBondContact O-N 2.98Å; I529-L531 VanDerWaalsContact C-N 3.34Å; I529-L531 PolarHBondContact O-N 3.17Å; I529-D532 PolarHBondContact O-N 2.62Å; I529-W533 HydrophobicContact CG2-CD2 4.06Å; I529-W533 HydrophobicContact CG2-CE3 4.46Å; I529-W533 HydrophobicContact CG2-CH2 4.11Å; I529-W533 HydrophobicContact CG2-CZ2 3.66Å; I529-W533 HydrophobicContact CG2-CZ3 4.48Å; I529-W533 PolarHBondContact O-N 3.21Å
530	V	89.7	Confident	84.3	Confident	67 Å²	67	68 Å²	68	41%	0.406	39%	0.387	S	S	.	.	H	α-helix	trans	-64.6	-41	178.1	170.5	0	0	0	0	110.8	L526 S527 D532 W533 I534	L526-V530 WeakPolarHBondContact O-CB 3.18Å; L526-V530 VanDerWaalsContact O-CG2 3.24Å; L526-V530 WeakPolarHBondContact O-CG2 3.48Å; L526-V530 PolarHBondContact O-N 3.06Å; S527-V530 PolarHBondContact O-N 3.36Å; V530-D532 VanDerWaalsContact C-N 3.34Å; V530-W533 PolarHBondContact O-N 3.48Å; V530-I534 HydrophobicContact CG1-CD1 3.86Å; V530-I534 WeakPolarHBondContact O-CD1 3.22Å; V530-I534 VanDerWaalsContact O-CG1 3.25Å; V530-I534 WeakPolarHBondContact O-CG1 3.41Å; V530-I534 PolarHBondContact O-N 2.92Å
531	L	89.2	Confident	81.7	Confident	83 Å²	83	68.2 Å²	68.2	44%	0.435	39%	0.394	S	S	.	.	H	α-helix	trans	-62.3	-41.3	174.5	-74.1	170.3	0	0	0	111.9	S527 L528 I529 I534 H535	S527-L531 WeakPolarHBondContact O-CB 3.35Å; S527-L531 WeakPolarHBondContact O-CG 3.43Å; S527-L531 PolarHBondContact O-N 3.46Å; L528-L531 PolarHBondContact O-N 3.06Å; I529-L531 VanDerWaalsContact C-N 3.34Å; I529-L531 PolarHBondContact O-N 3.17Å; L531-I534 PolarHBondContact O-N 3.18Å; L531-H535 PolarHBondContact O-CD2 2.82Å; L531-H535 PolarHBondContact O-N 2.92Å
532	D	86.3	Confident	78.7	Confident	17 Å²	17	75.5 Å²	75.5	9%	0.091	43%	0.428	C	S	.	.	H	α-helix	trans	-62.3	-44.2	176	-170.2	62.4	0	0	0	111.4	Y330 L528 I529 V530 I534 H535 H536	Y330-D532 HydrophobicContact CE2-CB 4.19Å; Y330-D532 WeakPolarHBondContact OH-CB 3.46Å; Y330-D532 PolarHBondContact OH-OD2 3.43Å; L528-D532 PolarHBondContact O-N 3.35Å; I529-D532 PolarHBondContact O-N 2.62Å; V530-D532 VanDerWaalsContact C-N 3.34Å; D532-I534 VanDerWaalsContact C-N 3.28Å; D532-I534 PolarHBondContact O-N 3.42Å; D532-H535 PolarHBondContact O-N 3.35Å; D532-H536 WeakPolarHBondContact O-CA 3.45Å; D532-H536 WeakPolarHBondContact O-CB 3.35Å; D532-H536 PolarHBondContact O-N 3.06Å; D532-H536 IonicContact OD1-CE1 3.66Å; D532-H536 IonicContact OD1-CG 3.9Å; D532-H536 IonicContact OD1-ND1 2.84Å; D532-H536 PolarHBondContact OD1-ND1 3.08Å
533	W	86.6	Confident	75.4	Confident	85 Å²	85	76.9 Å²	76.9	32%	0.322	45%	0.446	S	S	.	.	H	α-helix	trans	-64	-30.8	175.7	-66.9	-13.8	0	0	0	113.8	D472 F476 I529 V530 P537	D472-W533 HydrophobicContact CB-CZ2 4.32Å; D472-W533 PolarHBondContact OD1-NE1 3.05Å; F476-W533 HydrophobicContact CB-CH2 4.1Å; F476-W533 HydrophobicContact CB-CZ2 4.37Å; F476-W533 AromaticContact CD2-CH2 3.87Å; F476-W533 HydrophobicContact CD2-CH2 3.87Å; F476-W533 HydrophobicContact CD2-CZ3 4.43Å; F476-W533 HydrophobicContact CG-CH2 4.21Å; I529-W533 HydrophobicContact CG2-CD2 4.06Å; I529-W533 HydrophobicContact CG2-CE3 4.46Å; I529-W533 HydrophobicContact CG2-CH2 4.11Å; I529-W533 HydrophobicContact CG2-CZ2 3.66Å; I529-W533 HydrophobicContact CG2-CZ3 4.48Å; I529-W533 PolarHBondContact O-N 3.21Å; V530-W533 PolarHBondContact O-N 3.48Å; W533-P537 WeakPolarHBondContact O-CA 3.37Å
534	I	87.7	Confident	72	Confident	113 Å²	113	84.9 Å²	84.9	58%	0.579	48%	0.48	S	S	*	.	H	α-helix	trans	-72.5	-42.8	176.1	-70	165	0	0	0	110.8	V530 L531 D532	V530-I534 HydrophobicContact CG1-CD1 3.86Å; V530-I534 WeakPolarHBondContact O-CD1 3.22Å; V530-I534 VanDerWaalsContact O-CG1 3.25Å; V530-I534 WeakPolarHBondContact O-CG1 3.41Å; V530-I534 PolarHBondContact O-N 2.92Å; L531-I534 PolarHBondContact O-N 3.18Å; D532-I534 VanDerWaalsContact C-N 3.28Å; D532-I534 PolarHBondContact O-N 3.42Å
535	H	85.3	Confident	71	Confident	134 Å²	134	87.5 Å²	87.5	62%	0.62	49%	0.487	S	S	*	.	H	α-helix	trans	-82.7	-27.2	-177.4	-72.8	-61.8	0	0	0	113.5	L531 D532	L531-H535 PolarHBondContact O-CD2 2.82Å; L531-H535 PolarHBondContact O-N 2.92Å; D532-H535 PolarHBondContact O-N 3.35Å
536	H	80	Confident	69.8	Low	110 Å²	110	91.6 Å²	91.6	51%	0.509	51%	0.51	S	S	.	.	S	Bend	trans	-129.4	72.8	-179.6	-52.3	114.9	0	0	0	109.8	D532	D532-H536 WeakPolarHBondContact O-CA 3.45Å; D532-H536 WeakPolarHBondContact O-CB 3.35Å; D532-H536 PolarHBondContact O-N 3.06Å; D532-H536 IonicContact OD1-CE1 3.66Å; D532-H536 IonicContact OD1-CG 3.9Å; D532-H536 IonicContact OD1-ND1 2.84Å; D532-H536 PolarHBondContact OD1-ND1 3.08Å
537	P	71.9	Confident	68.5	Low	62 Å²	62	94.3 Å²	94.3	40%	0.403	53%	0.526	S	S	.	.			trans	-59.2	133	-175	20.4	-30.5	0	0	0	111.7	W533 G539 T540	W533-P537 WeakPolarHBondContact O-CA 3.37Å; P537-G539 PolarHBondContact O-N 3.45Å; P537-T540 HydrophobicContact CG-CG2 3.9Å; P537-T540 PolarHBondContact O-N 3.46Å; P537-T540 PolarHBondContact O-OG1 3.12Å
538	P	56.4	Low	67.1	Low	88 Å²	88	96.4 Å²	96.4	57%	0.571	53%	0.533	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.6	114.1	-179.4	19.4	-29	0	0	0	110.4	P468	P468-P538 HydrophobicContact CG-CB 3.87Å
539	G	53.9	Low	65.6	Low	59 Å²	59	96.8 Å²	96.8	61%	0.608	54%	0.536	S	S	*	.	T	Hydrogen-bonded Turn	trans	125.4	-11	179.1	0	0	0	0	0	115.6	P537	P537-G539 PolarHBondContact O-N 3.45Å
540	T	48.9	Very low	63.9	Low	91 Å²	91	103.2 Å²	103.2	56%	0.558	57%	0.572	S	S	*	*	G	3₁₀ helix	trans	-83.1	-10.8	178.5	53.1	0	0	0	0	114.6	P537 H542	P537-T540 HydrophobicContact CG-CG2 3.9Å; P537-T540 PolarHBondContact O-N 3.46Å; P537-T540 PolarHBondContact O-OG1 3.12Å; T540-H542 PolarHBondContact O-N 3.09Å
541	S	41.3	Very low	62.1	Low	112 Å²	112	105.8 Å²	105.8	78%	0.783	58%	0.584	S	S	*	*	G	3₁₀ helix	trans	-86.7	10.2	-178.5	-67.8	0	0	0	0	115.7	A543	S541-A543 PolarHBondContact O-N 3.3Å
542	H	32	Very low	60	Low	193 Å²	193	107.5 Å²	107.5	89%	0.894	60%	0.595	S	S	*	*	G	3₁₀ helix	trans	-81.7	7	168	-84.1	-57.2	0	0	0	113.9	T540	T540-H542 PolarHBondContact O-N 3.09Å
543	A	25.5	Very low	57.8	Low	69 Å²	69	115.1 Å²	115.1	57%	0.57	64%	0.637	S	S	*	*			trans	-132.3	69.5	175.6	0	0	0	0	0	109.6	S541	S541-A543 PolarHBondContact O-N 3.3Å
544	H	24.5	Very low	55.2	Low	265 Å²	265	117.8 Å²	117.8	100%	1.227	67%	0.666	S	S	*	*			trans	-162.3	0	147.2	-87.1	-48.1	0	0	0	110.7

Retrieved 544 of 544 residues in 356.8 ms (Link to these results)

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