A0A087XXJ9_POEFO Loading...

Lysosomal dipeptide transporter MFSD1

Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.

AlphaFold DB , UniProt , Accession A0A087XXJ9, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 462 aa.

Structure Viewer

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	42.6	Very low	36.2	Very low	217 Å²	217	150.5 Å²	150.5	100%	1.069	74%	0.741	S	S	*	*				0	-31.8	0	-78.6	-174.6	-164.8	0	0	112.3	D3 F4	M1-D3 VanDerWaalsContact C-N 3.29Å; M1-D3 PolarHBondContact O-N 2.91Å; M1-F4 PolarHBondContact O-N 3.49Å
2	A	37.4	Very low	35.6	Very low	79 Å²	79	142.7 Å²	142.7	65%	0.653	73%	0.728	S	S	*	*	H	α-helix	trans	-62.8	-31.9	170.2	0	0	0	0	0	113.8	F4 E5 E6	A2-F4 VanDerWaalsContact C-N 3.27Å; A2-F4 PolarHBondContact O-N 3.43Å; A2-E5 PolarHBondContact O-N 2.98Å; A2-E6 PolarHBondContact O-N 2.83Å
3	D	40.4	Very low	35.6	Very low	128 Å²	128	142.4 Å²	142.4	68%	0.684	73%	0.729	S	S	*	*	H	α-helix	trans	-76.8	-9.1	-176.5	-140.5	24.8	0	0	0	114.7	M1	M1-D3 VanDerWaalsContact C-N 3.29Å; M1-D3 PolarHBondContact O-N 2.91Å
4	F	33.5	Very low	35.9	Very low	167 Å²	167	146.1 Å²	146.1	73%	0.732	74%	0.742	S	S	*	*	H	α-helix	trans	-96.9	-20.8	176.8	-141	-91.5	0	0	0	112	M1 A2 R8	M1-F4 PolarHBondContact O-N 3.49Å; A2-F4 VanDerWaalsContact C-N 3.27Å; A2-F4 PolarHBondContact O-N 3.43Å; F4-R8 PolarHBondContact O-N 3.21Å
5	E	34.3	Very low	36.2	Very low	150 Å²	150	146.1 Å²	146.1	70%	0.701	74%	0.744	S	S	*	*	H	α-helix	trans	-79.5	-34.6	173.2	-83.6	175	153.9	0	0	111.6	A2 R8 S9	A2-E5 PolarHBondContact O-N 2.98Å; E5-R8 PolarHBondContact O-N 3.35Å; E5-S9 PolarHBondContact O-N 3.1Å
6	E	36.4	Very low	36.2	Very low	136 Å²	136	147.5 Å²	147.5	64%	0.636	75%	0.747	S	S	*	*	H	α-helix	trans	-72.9	-30.1	177	-155.9	166.1	-164.7	0	0	112.6	A2 R8 S9	A2-E6 PolarHBondContact O-N 2.83Å; E6-R8 VanDerWaalsContact C-N 3.34Å; E6-S9 PolarHBondContact O-OG 3.45Å; E6-S9 VanDerWaalsContact O-OG 3.13Å
7	R	32.5	Very low	36.1	Very low	198 Å²	198	148.4 Å²	148.4	75%	0.747	75%	0.754	S	S	*	*	H	α-helix	trans	-73.4	-23.1	169.5	-94	-175.4	-179	-159	1.7	113.9
8	R	29.7	Very low	36.4	Very low	192 Å²	192	150.6 Å²	150.6	73%	0.725	75%	0.752	S	S	*	*	H	α-helix	trans	-82.5	-22.8	177.6	-147.1	175.7	-174	-179.1	-0.5	112.1	F4 E5 E6 L10	F4-R8 PolarHBondContact O-N 3.21Å; E5-R8 PolarHBondContact O-N 3.35Å; E6-R8 VanDerWaalsContact C-N 3.34Å; R8-L10 PolarHBondContact O-N 3.23Å
9	S	34.6	Very low	36.5	Very low	96 Å²	96	145.6 Å²	145.6	67%	0.671	74%	0.743	S	S	*	*	S	Bend	trans	-74.2	-12.2	170.8	83.3	0	0	0	0	113.7	E5 E6	E5-S9 PolarHBondContact O-N 3.1Å; E6-S9 PolarHBondContact O-OG 3.45Å; E6-S9 VanDerWaalsContact O-OG 3.13Å
10	L	38.8	Very low	36.5	Very low	139 Å²	139	145.8 Å²	145.8	73%	0.728	75%	0.754	S	S	*	*	S	Bend	trans	-100.8	-10.6	178.7	-73	166.9	0	0	0	113.7	R8	R8-L10 PolarHBondContact O-N 3.23Å
11	L	37.5	Very low	36.9	Very low	153 Å²	153	142 Å²	142	80%	0.801	75%	0.75	S	S	*	*	S	Bend	trans	-148.1	79.8	-177.6	-71.4	171.5	0	0	0	110.4
12	G	29.8	Very low	37.2	Very low	57 Å²	57	142.9 Å²	142.9	59%	0.588	74%	0.742	S	S	*	*	S	Bend	trans	144.4	83.4	166.4	0	0	0	0	0	114.8
13	D	35.4	Very low	38	Very low	139 Å²	139	148.6 Å²	148.6	74%	0.743	76%	0.755	S	S	*	*				162.9	80.4	121.8	-88.3	-25.5	0	0	0	108.9	N15	D13-N15 PolarHBondContact O-N 3.1Å
14	E	39.5	Very low	39	Very low	195 Å²	195	146.1 Å²	146.1	91%	0.911	74%	0.741	S	S	*	*	S	Bend	trans	-75.4	9.8	168.3	-82.3	-167.4	148	0	0	112.9
15	N	39.9	Very low	40.9	Very low	145 Å²	145	142 Å²	142	78%	0.775	73%	0.733	S	S	*	*	S	Bend	trans	-142.9	70.7	180	-77.2	-47.9	0	0	0	111.3	D13	D13-N15 PolarHBondContact O-N 3.1Å
16	E	36.5	Very low	42.5	Very low	169 Å²	169	136.5 Å²	136.5	79%	0.79	71%	0.713	S	S	*	*	S	Bend	trans	-154.6	136	149.7	-112.8	163.2	-158.2	0	0	111.3
17	D	35.3	Very low	44.2	Very low	162 Å²	162	134.6 Å²	134.6	87%	0.866	71%	0.707	S	S	*	*			trans	72.6	52.1	178.5	-72.4	-9.3	0	0	0	119.8
18	R	40.8	Very low	46.1	Very low	189 Å²	189	127.3 Å²	127.3	71%	0.713	69%	0.685	S	S	*	*			trans	-91.4	106.7	139	-71.6	-175.9	-179.9	-179.2	1.5	107.9
19	G	38.3	Very low	48.2	Very low	56 Å²	56	119.4 Å²	119.4	58%	0.577	66%	0.658	S	S	*	*			trans	-51.9	173.5	168.1	0	0	0	0	0	111.9	G21	G19-G21 PolarHBondContact O-N 3.3Å
20	P	37.8	Very low	50.1	Low	149 Å²	149	115 Å²	115	97%	0.968	63%	0.627	S	S	*	*	S	Bend	trans	-72.9	65.3	-166.4	32.5	-35.6	0	0	0	112.4
21	G	43.2	Very low	51.7	Low	65 Å²	65	111.4 Å²	111.4	67%	0.67	61%	0.613	S	S	*	*			trans	-95.4	104	170.6	0	0	0	0	0	107.7	G19 Q23	G19-G21 PolarHBondContact O-N 3.3Å; G21-Q23 PolarHBondContact O-N 3.19Å
22	R	49	Very low	53.8	Low	237 Å²	237	107.7 Å²	107.7	89%	0.894	59%	0.591	S	S	*	*			trans	-4.2	107.4	164.2	-145.2	176.4	-170.3	-179.3	2.2	113.4	L24	R22-L24 PolarHBondContact O-N 3.11Å
23	Q	54.8	Low	56.2	Low	198 Å²	198	109.4 Å²	109.4	93%	0.925	59%	0.59	S	S	*	*			trans	-47.5	110.1	173.4	-86.7	177.2	-13.2	0	0	109.1	G21	G21-Q23 PolarHBondContact O-N 3.19Å
24	L	62	Low	58.5	Low	77 Å²	77	107 Å²	107	40%	0.403	58%	0.577	S	S	.	*			trans	-67.8	137.8	178.4	-74.1	164.4	0	0	0	107.9	R22 C28 D29 I236	R22-L24 PolarHBondContact O-N 3.11Å; L24-C28 HydrophobicContact CB-CB 4.4Å; L24-C28 HydrophobicContact CD2-CB 4.37Å; L24-D29 HydrophobicContact CB-CB 4.12Å; L24-I236 HydrophobicContact CD1-CD1 4.12Å; L24-I236 HydrophobicContact CD1-CG2 4.47Å
25	S	72.6	Confident	60.7	Low	79 Å²	79	97.8 Å²	97.8	55%	0.552	53%	0.534	S	S	*	.			trans	-53.4	148.3	170.4	171.9	0	0	0	0	110.1	I27 C28 D29	S25-I27 PolarHBondContact O-N 3.09Å; S25-C28 CarbonylContact O-C 3.53Å; S25-C28 VanDerWaalsContact O-CA 3.29Å; S25-C28 WeakPolarHBondContact O-CA 3.47Å; S25-C28 WeakPolarHBondContact O-CB 3.48Å; S25-C28 PolarHBondContact O-N 3.14Å; S25-D29 PolarHBondContact O-N 3.47Å
26	A	68.9	Low	62.8	Low	36 Å²	36	93.2 Å²	93.2	30%	0.298	51%	0.506	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56.9	-22.3	-176.4	0	0	0	0	0	115.1	H32 L34	A26-H32 WeakPolarHBondContact O-CB 3.4Å; A26-H32 PolarHBondContact O-ND1 3.1Å; A26-L34 HydrophobicContact CB-CD1 3.88Å
27	I	70.9	Confident	65.3	Low	96 Å²	96	88.4 Å²	88.4	49%	0.492	49%	0.488	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.4	-19.5	173.6	-67	167	0	0	0	111.7	S25 L34 H35 V38	S25-I27 PolarHBondContact O-N 3.09Å; I27-L34 HydrophobicContact CG1-CB 4.33Å; I27-H35 PolarHBondContact O-ND1 2.55Å; I27-V38 HydrophobicContact CG2-CG2 4.31Å
28	C	72	Confident	67.9	Low	44 Å²	44	82.7 Å²	82.7	30%	0.297	46%	0.459	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102.7	-11.3	-175.8	-88.3	0	0	0	0	113.5	L24 S25 P30 R232	L24-C28 HydrophobicContact CB-CB 4.4Å; L24-C28 HydrophobicContact CD2-CB 4.37Å; S25-C28 CarbonylContact O-C 3.53Å; S25-C28 VanDerWaalsContact O-CA 3.29Å; S25-C28 WeakPolarHBondContact O-CA 3.47Å; S25-C28 WeakPolarHBondContact O-CB 3.48Å; S25-C28 PolarHBondContact O-N 3.14Å; C28-P30 WeakPolarHBondContact O-CD 3.24Å; C28-R232 PolarHBondContact O-NH2 3.36Å
29	D	75.1	Confident	70.3	Confident	27 Å²	27	73.7 Å²	73.7	14%	0.144	43%	0.425	C	S	.	.			trans	-89.1	113.9	175.4	-176.7	12.9	0	0	0	110.7	L24 S25 S31 H32 H35	L24-D29 HydrophobicContact CB-CB 4.12Å; S25-D29 PolarHBondContact O-N 3.47Å; D29-S31 VanDerWaalsContact CG-OG 3.27Å; D29-S31 PolarHBondContact O-N 3.42Å; D29-S31 PolarHBondContact OD1-N 2.97Å; D29-S31 PolarHBondContact OD1-OG 3.46Å; D29-S31 PolarHBondContact OD2-OG 3.31Å; D29-S31 VanDerWaalsContact OD2-OG 3.05Å; D29-H32 HydrophobicContact CB-CB 3.99Å; D29-H32 WeakPolarHBondContact O-CB 3.34Å; D29-H32 PolarHBondContact O-N 3.13Å; D29-H35 WeakPolarHBondContact O-CB 3.31Å
30	P	74.1	Confident	72.8	Confident	4 Å²	4	72.1 Å²	72.1	3%	0.026	40%	0.403	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61.9	-23.7	-178.3	-22.6	34.8	0	0	0	115.3	C28 H32 H35 A233 I236 L237	C28-P30 WeakPolarHBondContact O-CD 3.24Å; P30-H32 VanDerWaalsContact C-N 3.31Å; P30-H35 VanDerWaalsContact CA-CD2 3.5Å; P30-H35 WeakPolarHBondContact CA-CD2 3.44Å; P30-A233 HydrophobicContact CB-CB 3.78Å; P30-A233 HydrophobicContact CG-CB 4.09Å; P30-I236 HydrophobicContact CG-CB 4.25Å; P30-I236 HydrophobicContact CG-CD1 3.97Å; P30-I236 HydrophobicContact CG-CG2 4.28Å; P30-L237 HydrophobicContact CB-CD1 3.73Å; P30-L237 HydrophobicContact CB-CG 4.09Å
31	S	71.8	Confident	75.4	Confident	62 Å²	62	69.1 Å²	69.1	43%	0.434	38%	0.378	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.7	-17.7	173.6	31.4	0	0	0	0	113.4	D29	D29-S31 VanDerWaalsContact CG-OG 3.27Å; D29-S31 PolarHBondContact O-N 3.42Å; D29-S31 PolarHBondContact OD1-N 2.97Å; D29-S31 PolarHBondContact OD1-OG 3.46Å; D29-S31 PolarHBondContact OD2-OG 3.31Å; D29-S31 VanDerWaalsContact OD2-OG 3.05Å
32	H	83	Confident	77.8	Confident	75 Å²	75	68.8 Å²	68.8	35%	0.347	36%	0.358	S	S	.	.	S	Bend	trans	-84.3	142.4	-173.2	-165.7	-86.1	0	0	0	112.4	A26 D29 P30 L34 H35 R36	A26-H32 WeakPolarHBondContact O-CB 3.4Å; A26-H32 PolarHBondContact O-ND1 3.1Å; D29-H32 HydrophobicContact CB-CB 3.99Å; D29-H32 WeakPolarHBondContact O-CB 3.34Å; D29-H32 PolarHBondContact O-N 3.13Å; P30-H32 VanDerWaalsContact C-N 3.31Å; H32-L34 VanDerWaalsContact C-N 3.28Å; H32-L34 PolarHBondContact ND1-N 3.45Å; H32-L34 PolarHBondContact O-N 3.13Å; H32-H35 WeakPolarHBondContact O-CB 3.33Å; H32-H35 PolarHBondContact O-N 3.29Å; H32-R36 PolarHBondContact O-N 3.18Å
33	V	79.6	Confident	79.8	Confident	94 Å²	94	57.5 Å²	57.5	57%	0.57	32%	0.315	S	S	*	.	H	α-helix	trans	-55.7	-41	-176.8	178.5	0	0	0	0	112.1	H35 R36 V37	V33-H35 VanDerWaalsContact C-N 3.32Å; V33-H35 PolarHBondContact O-N 2.96Å; V33-R36 PolarHBondContact O-N 3.32Å; V33-R36 VanDerWaalsContact O-N 3.17Å; V33-V37 HydrophobicContact CG1-CG2 4.36Å; V33-V37 WeakPolarHBondContact O-CG2 3.49Å; V33-V37 PolarHBondContact O-N 3.2Å
34	L	83.2	Confident	81.5	Confident	87 Å²	87	48.7 Å²	48.7	46%	0.455	28%	0.276	S	S	.	.	H	α-helix	trans	-60.6	-38.6	178.6	-68.2	173.9	0	0	0	112.8	A26 I27 H32 V37 V38	A26-L34 HydrophobicContact CB-CD1 3.88Å; I27-L34 HydrophobicContact CG1-CB 4.33Å; H32-L34 VanDerWaalsContact C-N 3.28Å; H32-L34 PolarHBondContact ND1-N 3.45Å; H32-L34 PolarHBondContact O-N 3.13Å; L34-V37 PolarHBondContact O-N 3.15Å; L34-V38 WeakPolarHBondContact O-CG2 3.43Å; L34-V38 PolarHBondContact O-N 3.41Å
35	H	85.1	Confident	83.1	Confident	2 Å²	2	48.3 Å²	48.3	1%	0.009	27%	0.271	C	S	.	.	H	α-helix	trans	-67.2	-42.8	175.4	-172.8	79.9	0	0	0	111.5	I27 D29 P30 H32 V33 V37 V38 V39 W158	I27-H35 PolarHBondContact O-ND1 2.55Å; D29-H35 WeakPolarHBondContact O-CB 3.31Å; P30-H35 VanDerWaalsContact CA-CD2 3.5Å; P30-H35 WeakPolarHBondContact CA-CD2 3.44Å; H32-H35 WeakPolarHBondContact O-CB 3.33Å; H32-H35 PolarHBondContact O-N 3.29Å; V33-H35 VanDerWaalsContact C-N 3.32Å; V33-H35 PolarHBondContact O-N 2.96Å; H35-V37 VanDerWaalsContact C-N 3.27Å; H35-V37 PolarHBondContact O-N 2.89Å; H35-V38 WeakPolarHBondContact O-CB 3.42Å; H35-V38 PolarHBondContact O-N 3.3Å; H35-V38 VanDerWaalsContact O-N 3.11Å; H35-V39 WeakPolarHBondContact O-CG2 3.25Å; H35-V39 PolarHBondContact O-N 3.14Å; H35-W158 AromaticContact CD2-CH2 3.94Å; H35-W158 AromaticContact CD2-CZ3 3.82Å; H35-W158 AromaticContact NE2-CH2 3.75Å
36	R	85.8	Confident	84.1	Confident	50 Å²	50	44.5 Å²	44.5	19%	0.189	24%	0.244	C	C	.	.	H	α-helix	trans	-60.4	-38.1	176	-62.8	177.8	71.1	-143.6	-3.7	111.3	H32 V33 V39 L40 W158 F159 E163	H32-R36 PolarHBondContact O-N 3.18Å; V33-R36 PolarHBondContact O-N 3.32Å; V33-R36 VanDerWaalsContact O-N 3.17Å; R36-V39 PolarHBondContact O-N 3.35Å; R36-L40 WeakPolarHBondContact O-CB 3.43Å; R36-L40 PolarHBondContact O-N 2.9Å; R36-W158 PolarHBondContact NE-O 2.87Å; R36-W158 PolarHBondContact NH2-O 3.3Å; R36-F159 HydrophobicContact CB-CE1 4.13Å; R36-F159 HydrophobicContact CB-CZ 4.27Å; R36-F159 WeakPolarHBondContact O-CZ 3.43Å; R36-E163 IonicContact CZ-OE2 2.66Å; R36-E163 IonicContact NH1-OE1 2.8Å; R36-E163 IonicContact NH1-OE2 3.17Å; R36-E163 PolarHBondContact NH1-OE2 2.95Å; R36-E163 IonicContact NH2-OE2 2.64Å; R36-E163 PolarHBondContact NH2-OE2 3.49Å
37	V	87.3	Confident	85.1	Confident	68 Å²	68	43 Å²	43	41%	0.412	23%	0.232	S	C	.	.	H	α-helix	trans	-64.1	-43	173.1	171.9	0	0	0	0	111.8	V33 L34 H35 V39 L40 I41	V33-V37 HydrophobicContact CG1-CG2 4.36Å; V33-V37 WeakPolarHBondContact O-CG2 3.49Å; V33-V37 PolarHBondContact O-N 3.2Å; L34-V37 PolarHBondContact O-N 3.15Å; H35-V37 VanDerWaalsContact C-N 3.27Å; H35-V37 PolarHBondContact O-N 2.89Å; V37-V39 VanDerWaalsContact C-N 3.32Å; V37-V39 PolarHBondContact O-N 2.99Å; V37-L40 WeakPolarHBondContact O-CB 3.14Å; V37-L40 PolarHBondContact O-N 3.33Å; V37-I41 HydrophobicContact CG1-CD1 4.24Å; V37-I41 WeakPolarHBondContact O-CG1 3.34Å; V37-I41 PolarHBondContact O-N 3Å
38	V	90.1	Very high	86.2	Confident	42 Å²	42	39.8 Å²	39.8	26%	0.255	22%	0.215	S	C	.	.	H	α-helix	trans	-59.8	-44.7	175.1	170.9	0	0	0	0	111	I27 L34 H35 L40 I41 F42 L229	I27-V38 HydrophobicContact CG2-CG2 4.31Å; L34-V38 WeakPolarHBondContact O-CG2 3.43Å; L34-V38 PolarHBondContact O-N 3.41Å; H35-V38 WeakPolarHBondContact O-CB 3.42Å; H35-V38 PolarHBondContact O-N 3.3Å; H35-V38 VanDerWaalsContact O-N 3.11Å; V38-L40 VanDerWaalsContact C-N 3.34Å; V38-L40 PolarHBondContact O-N 3.46Å; V38-I41 PolarHBondContact O-N 3.47Å; V38-F42 HydrophobicContact CG1-CD2 4.05Å; V38-F42 HydrophobicContact CG1-CE2 3.84Å; V38-F42 VanDerWaalsContact O-CD2 3.28Å; V38-F42 WeakPolarHBondContact O-CD2 3.34Å; V38-F42 PolarHBondContact O-N 3.42Å; V38-L229 HydrophobicContact CG1-CD1 4.4Å
39	V	91.4	Very high	87.3	Confident	0 Å²	0	37.7 Å²	37.7	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-61.5	-43.2	176.1	172.2	0	0	0	0	111	H35 R36 V37 I41 F42 M43 W158 L226 L229	H35-V39 WeakPolarHBondContact O-CG2 3.25Å; H35-V39 PolarHBondContact O-N 3.14Å; R36-V39 PolarHBondContact O-N 3.35Å; V37-V39 VanDerWaalsContact C-N 3.32Å; V37-V39 PolarHBondContact O-N 2.99Å; V39-I41 VanDerWaalsContact C-N 3.32Å; V39-I41 PolarHBondContact O-N 2.71Å; V39-F42 PolarHBondContact O-N 3.48Å; V39-M43 HydrophobicContact CG1-CE 3.91Å; V39-M43 VanDerWaalsContact O-CB 3.29Å; V39-M43 WeakPolarHBondContact O-CB 3.2Å; V39-M43 PolarHBondContact O-N 2.9Å; V39-W158 HydrophobicContact CB-CD2 4.48Å; V39-W158 HydrophobicContact CB-CE3 4.25Å; V39-W158 HydrophobicContact CB-CH2 4.46Å; V39-W158 HydrophobicContact CB-CZ3 4.27Å; V39-W158 HydrophobicContact CG1-CD2 3.69Å; V39-W158 HydrophobicContact CG1-CE3 3.94Å; V39-W158 HydrophobicContact CG1-CG 4.08Å; V39-W158 HydrophobicContact CG1-CH2 4.34Å; V39-W158 HydrophobicContact CG1-CZ2 4.1Å; V39-W158 HydrophobicContact CG1-CZ3 4.29Å; V39-W158 HydrophobicContact CG2-CE3 4.18Å; V39-W158 HydrophobicContact CG2-CH2 3.58Å; V39-W158 HydrophobicContact CG2-CZ2 4Å; V39-W158 HydrophobicContact CG2-CZ3 3.7Å; V39-L226 HydrophobicContact CG1-CD2 3.87Å; V39-L229 HydrophobicContact CG2-CB 4.31Å; V39-L229 HydrophobicContact CG2-CD1 3.88Å
40	L	90.6	Very high	88.3	Confident	23 Å²	23	36.8 Å²	36.8	12%	0.12	20%	0.196	C	C	.	.	H	α-helix	trans	-58.7	-42.3	175.8	-179.9	56.9	0	0	0	112.3	R36 V37 V38 F42 M43 C44 F159 V167 L170	R36-L40 WeakPolarHBondContact O-CB 3.43Å; R36-L40 PolarHBondContact O-N 2.9Å; V37-L40 WeakPolarHBondContact O-CB 3.14Å; V37-L40 PolarHBondContact O-N 3.33Å; V38-L40 VanDerWaalsContact C-N 3.34Å; V38-L40 PolarHBondContact O-N 3.46Å; L40-F42 PolarHBondContact O-N 2.98Å; L40-M43 CarbonylContact O-C 3.32Å; L40-M43 WeakPolarHBondContact O-CB 3.01Å; L40-M43 PolarHBondContact O-N 3.16Å; L40-C44 PolarHBondContact O-N 2.88Å; L40-C44 PolarHBondContact O-SG 2.99Å; L40-C44 VanDerWaalsContact O-SG 3.33Å; L40-F159 HydrophobicContact CB-CE2 4.4Å; L40-F159 HydrophobicContact CB-CZ 3.89Å; L40-F159 HydrophobicContact CD1-CE2 4.44Å; L40-V167 HydrophobicContact CD1-CB 4.12Å; L40-V167 HydrophobicContact CD1-CG1 3.62Å; L40-V167 HydrophobicContact CD1-CG2 3.76Å; L40-V167 HydrophobicContact CD2-CG2 4.21Å; L40-L170 HydrophobicContact CD2-CD1 3.99Å
41	I	92.2	Very high	89.3	Confident	85 Å²	85	39.5 Å²	39.5	44%	0.436	21%	0.206	S	C	.	.	H	α-helix	trans	-58.3	-52.2	178.1	-70.2	166.1	0	0	0	110.4	V37 V38 V39 M43 C44 F45	V37-I41 HydrophobicContact CG1-CD1 4.24Å; V37-I41 WeakPolarHBondContact O-CG1 3.34Å; V37-I41 PolarHBondContact O-N 3Å; V38-I41 PolarHBondContact O-N 3.47Å; V39-I41 VanDerWaalsContact C-N 3.32Å; V39-I41 PolarHBondContact O-N 2.71Å; I41-M43 VanDerWaalsContact C-N 3.26Å; I41-M43 PolarHBondContact O-N 3.43Å; I41-C44 PolarHBondContact O-N 3.31Å; I41-F45 HydrophobicContact CG2-CD2 3.93Å; I41-F45 HydrophobicContact CG2-CE2 4.01Å; I41-F45 VanDerWaalsContact O-CD2 3.27Å; I41-F45 WeakPolarHBondContact O-CD2 3.42Å; I41-F45 PolarHBondContact O-N 3.44Å; I41-F45 VanDerWaalsContact O-N 3.12Å
42	F	93.8	Very high	90.5	Very high	58 Å²	58	37.1 Å²	37.1	25%	0.254	19%	0.188	S	C	.	.	H	α-helix	trans	-63.8	-35.3	177.8	-73.9	-72.4	0	0	0	112.1	V38 V39 L40 F45 L46 C222 V225 L226 L229	V38-F42 HydrophobicContact CG1-CD2 4.05Å; V38-F42 HydrophobicContact CG1-CE2 3.84Å; V38-F42 VanDerWaalsContact O-CD2 3.28Å; V38-F42 WeakPolarHBondContact O-CD2 3.34Å; V38-F42 PolarHBondContact O-N 3.42Å; V39-F42 PolarHBondContact O-N 3.48Å; L40-F42 PolarHBondContact O-N 2.98Å; F42-F45 PolarHBondContact O-N 2.92Å; F42-L46 PolarHBondContact O-N 3.19Å; F42-C222 HydrophobicContact CD1-CB 4.04Å; F42-V225 HydrophobicContact CD1-CB 4.28Å; F42-V225 HydrophobicContact CD1-CG1 4.12Å; F42-V225 HydrophobicContact CD2-CG1 3.91Å; F42-V225 HydrophobicContact CE1-CB 4.23Å; F42-V225 HydrophobicContact CE1-CG1 3.95Å; F42-V225 HydrophobicContact CE1-CG2 4.37Å; F42-V225 HydrophobicContact CE2-CG1 3.74Å; F42-V225 HydrophobicContact CG-CG1 4.12Å; F42-V225 HydrophobicContact CZ-CG1 3.76Å; F42-L226 HydrophobicContact CB-CD1 4.19Å; F42-L226 HydrophobicContact CB-CD2 3.71Å; F42-L226 HydrophobicContact CB-CG 3.7Å; F42-L229 HydrophobicContact CD2-CD1 4.26Å
43	M	92.1	Very high	91.2	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-64.2	-41.2	176.5	-160.4	-178.6	-62.9	0	0	111.5	V39 L40 I41 L46 Q151 Y154 A155 W158 F159 V167 Q171 L226	V39-M43 HydrophobicContact CG1-CE 3.91Å; V39-M43 VanDerWaalsContact O-CB 3.29Å; V39-M43 WeakPolarHBondContact O-CB 3.2Å; V39-M43 PolarHBondContact O-N 2.9Å; L40-M43 CarbonylContact O-C 3.32Å; L40-M43 WeakPolarHBondContact O-CB 3.01Å; L40-M43 PolarHBondContact O-N 3.16Å; I41-M43 VanDerWaalsContact C-N 3.26Å; I41-M43 PolarHBondContact O-N 3.43Å; M43-L46 VanDerWaalsContact O-CB 3.3Å; M43-L46 WeakPolarHBondContact O-CB 3.15Å; M43-L46 PolarHBondContact O-N 2.96Å; M43-Q151 HydrophobicContact CG-CG 4.2Å; M43-Q151 PolarHBondContact O-NE2 3.47Å; M43-Y154 HydrophobicContact CE-CG 4.46Å; M43-A155 VanDerWaalsContact SD-CA 3.54Å; M43-A155 HydrophobicContact SD-CB 3.91Å; M43-A155 PolarHBondContact SD-N 3.49Å; M43-A155 VanDerWaalsContact SD-N 3.37Å; M43-W158 HydrophobicContact CE-CB 4.28Å; M43-W158 HydrophobicContact CE-CG 4.3Å; M43-F159 HydrophobicContact CE-CE2 4.25Å; M43-V167 HydrophobicContact SD-CG1 4.44Å; M43-Q171 VanDerWaalsContact CG-NE2 3.27Å; M43-Q171 PolarHBondContact SD-NE2 3.11Å; M43-L226 HydrophobicContact CB-CD1 4.43Å; M43-L226 HydrophobicContact CB-CD2 4.46Å
44	C	91	Very high	92	Very high	14 Å²	14	30.1 Å²	30.1	10%	0.095	15%	0.149	C	C	.	.	H	α-helix	trans	-65	-38.9	174.9	-70.2	0	0	0	0	112.4	L40 I41 L46 M174	L40-C44 PolarHBondContact O-N 2.88Å; L40-C44 PolarHBondContact O-SG 2.99Å; L40-C44 VanDerWaalsContact O-SG 3.33Å; I41-C44 PolarHBondContact O-N 3.31Å; C44-L46 VanDerWaalsContact C-N 3.33Å; C44-M174 HydrophobicContact CB-CB 4.12Å; C44-M174 HydrophobicContact CB-CG 4.14Å; C44-M174 VanDerWaalsContact O-CG 3.25Å; C44-M174 WeakPolarHBondContact O-CG 3.4Å
45	F	93.8	Very high	92.6	Very high	68 Å²	68	26.1 Å²	26.1	30%	0.298	13%	0.128	S	C	.	.	H	α-helix	trans	-79.5	-12.1	179	-77.8	-64.8	0	0	0	114.6	I41 F42 G47 F48 M174 F218 S219	I41-F45 HydrophobicContact CG2-CD2 3.93Å; I41-F45 HydrophobicContact CG2-CE2 4.01Å; I41-F45 VanDerWaalsContact O-CD2 3.27Å; I41-F45 WeakPolarHBondContact O-CD2 3.42Å; I41-F45 PolarHBondContact O-N 3.44Å; I41-F45 VanDerWaalsContact O-N 3.12Å; F42-F45 PolarHBondContact O-N 2.92Å; F45-G47 VanDerWaalsContact C-N 3.32Å; F45-G47 PolarHBondContact O-N 3Å; F45-F48 HydrophobicContact CD1-CB 4.16Å; F45-F48 HydrophobicContact CD1-CD2 4.36Å; F45-F48 HydrophobicContact CD1-CG 4.27Å; F45-F48 HydrophobicContact CE1-CD2 4.49Å; F45-F48 WeakPolarHBondContact O-CB 3.37Å; F45-F48 PolarHBondContact O-N 2.94Å; F45-F48 VanDerWaalsContact O-N 3.16Å; F45-M174 HydrophobicContact CD1-CG 4.45Å; F45-M174 HydrophobicContact CD1-SD 4.36Å; F45-M174 HydrophobicContact CE1-SD 3.94Å; F45-M174 HydrophobicContact CZ-SD 4.45Å; F45-F218 HydrophobicContact CB-CE1 3.78Å; F45-F218 HydrophobicContact CB-CZ 4.22Å; F45-F218 AromaticContact CD1-CE1 3.67Å; F45-F218 HydrophobicContact CD1-CE1 3.67Å; F45-F218 HydrophobicContact CD1-CZ 4.26Å; F45-F218 HydrophobicContact CE1-CE1 4.43Å; F45-F218 AromaticContact CG-CE1 3.8Å; F45-F218 HydrophobicContact CG-CE1 3.8Å; F45-F218 HydrophobicContact CG-CZ 4.1Å; F45-S219 PolarHBondContact O-OG 3.1Å
46	L	93.7	Very high	93.1	Very high	0 Å²	0	26 Å²	26	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-56.8	-44.3	177.9	-177.9	63.9	0	0	0	112.3	F42 M43 C44 T107 L147 Q151 S219 A223 L226	F42-L46 PolarHBondContact O-N 3.19Å; M43-L46 VanDerWaalsContact O-CB 3.3Å; M43-L46 WeakPolarHBondContact O-CB 3.15Å; M43-L46 PolarHBondContact O-N 2.96Å; C44-L46 VanDerWaalsContact C-N 3.33Å; L46-T107 HydrophobicContact CD1-CG2 3.81Å; L46-T107 HydrophobicContact CD2-CG2 3.66Å; L46-T107 HydrophobicContact CG-CG2 4.31Å; L46-L147 HydrophobicContact CD1-CD1 4.09Å; L46-L147 HydrophobicContact CD2-CD1 4.27Å; L46-L147 HydrophobicContact CG-CD1 4.03Å; L46-Q151 HydrophobicContact CD2-CB 3.96Å; L46-Q151 HydrophobicContact CD2-CG 4.14Å; L46-S219 VanDerWaalsContact O-CB 3.26Å; L46-S219 WeakPolarHBondContact O-CB 3.37Å; L46-S219 PolarHBondContact O-OG 2.66Å; L46-A223 HydrophobicContact CD1-CB 3.53Å; L46-L226 HydrophobicContact CB-CD1 4.27Å; L46-L226 HydrophobicContact CD1-CD1 4.37Å; L46-L226 HydrophobicContact CD2-CD1 4.11Å; L46-L226 HydrophobicContact CG-CD1 4.5Å
47	G	90.9	Very high	93.6	Very high	4 Å²	4	23.6 Å²	23.6	4%	0.041	12%	0.118	C	C	.	.	T	Hydrogen-bonded Turn	trans	-81.9	-15	178.9	0	0	0	0	0	114.4	F45 G49 S50 Y51	F45-G47 VanDerWaalsContact C-N 3.32Å; F45-G47 PolarHBondContact O-N 3Å; G47-G49 PolarHBondContact O-N 3.48Å; G47-S50 WeakPolarHBondContact O-CB 3.43Å; G47-S50 PolarHBondContact O-N 3.28Å; G47-Y51 WeakPolarHBondContact O-CD2 3.37Å; G47-Y51 PolarHBondContact O-N 3.16Å; G47-Y51 VanDerWaalsContact O-N 3.13Å
48	F	94.2	Very high	94	Very high	29 Å²	29	20.4 Å²	20.4	13%	0.127	10%	0.098	C	C	.	.	H	α-helix	trans	-55.2	-50.2	-167.1	-178.3	-88.3	0	0	0	113.3	F45 S50 Y51 F52 M174 G178 V181 T215	F45-F48 HydrophobicContact CD1-CB 4.16Å; F45-F48 HydrophobicContact CD1-CD2 4.36Å; F45-F48 HydrophobicContact CD1-CG 4.27Å; F45-F48 HydrophobicContact CE1-CD2 4.49Å; F45-F48 WeakPolarHBondContact O-CB 3.37Å; F45-F48 PolarHBondContact O-N 2.94Å; F45-F48 VanDerWaalsContact O-N 3.16Å; F48-S50 VanDerWaalsContact C-N 3.3Å; F48-S50 PolarHBondContact O-N 3.43Å; F48-Y51 PolarHBondContact O-N 3.44Å; F48-F52 HydrophobicContact CE1-CB 4.47Å; F48-F52 HydrophobicContact CE1-CD2 4.15Å; F48-F52 HydrophobicContact CZ-CD2 4.33Å; F48-F52 WeakPolarHBondContact O-CB 3.48Å; F48-F52 PolarHBondContact O-N 2.95Å; F48-M174 HydrophobicContact CD2-CG 4.36Å; F48-M174 HydrophobicContact CD2-SD 4Å; F48-M174 HydrophobicContact CE2-SD 4.45Å; F48-G178 VanDerWaalsContact CE2-CA 3.48Å; F48-V181 HydrophobicContact CZ-CB 4.46Å; F48-T215 HydrophobicContact CE1-CG2 4.32Å
49	G	94.6	Very high	94.2	Very high	0 Å²	0	18.4 Å²	18.4	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-65.5	-31.5	179.7	0	0	0	0	0	113.5	G47 C53 S219	G47-G49 PolarHBondContact O-N 3.48Å; G49-C53 VanDerWaalsContact O-CB 3.31Å; G49-C53 WeakPolarHBondContact O-CB 3.42Å; G49-C53 PolarHBondContact O-N 3.15Å; G49-S219 PolarHBondContact N-OG 3.45Å
50	S	95.8	Very high	94.4	Very high	7 Å²	7	18.4 Å²	18.4	5%	0.049	9%	0.086	C	C	.	.	H	α-helix	trans	-64.3	-52	174.8	-174.9	0	0	0	0	110.7	G47 F48 C53 Y54 F140	G47-S50 WeakPolarHBondContact O-CB 3.43Å; G47-S50 PolarHBondContact O-N 3.28Å; F48-S50 VanDerWaalsContact C-N 3.3Å; F48-S50 PolarHBondContact O-N 3.43Å; S50-C53 PolarHBondContact O-N 3.15Å; S50-Y54 VanDerWaalsContact O-CB 3.22Å; S50-Y54 WeakPolarHBondContact O-CB 3.5Å; S50-Y54 PolarHBondContact O-N 2.93Å; S50-F140 WeakPolarHBondContact O-CZ 3.34Å
51	Y	95.1	Very high	94.5	Very high	62 Å²	62	17.3 Å²	17.3	24%	0.243	8%	0.081	C	C	.	.	H	α-helix	trans	-68	-38.1	179.4	-75.3	-84.3	0	0	0	112.9	G47 F48 A175 S179	G47-Y51 WeakPolarHBondContact O-CD2 3.37Å; G47-Y51 PolarHBondContact O-N 3.16Å; G47-Y51 VanDerWaalsContact O-N 3.13Å; F48-Y51 PolarHBondContact O-N 3.44Å; Y51-A175 VanDerWaalsContact CB-O 3.27Å; Y51-A175 WeakPolarHBondContact CB-O 3.4Å; Y51-A175 HydrophobicContact CD1-CB 3.92Å; Y51-A175 HydrophobicContact CD2-CB 3.34Å; Y51-A175 HydrophobicContact CE1-CB 3.86Å; Y51-A175 HydrophobicContact CE2-CB 3.3Å; Y51-A175 HydrophobicContact CG-CB 3.67Å; Y51-S179 PolarHBondContact O-OG 2.93Å
52	F	97.1	Very high	94.5	Very high	11 Å²	11	14.5 Å²	14.5	5%	0.048	7%	0.067	C	C	.	.	H	α-helix	trans	-57.8	-54	173.3	-173.7	-73.1	0	0	0	110.8	F48 D55 G178 V181 N182 M186 A212 T215	F48-F52 HydrophobicContact CE1-CB 4.47Å; F48-F52 HydrophobicContact CE1-CD2 4.15Å; F48-F52 HydrophobicContact CZ-CD2 4.33Å; F48-F52 WeakPolarHBondContact O-CB 3.48Å; F48-F52 PolarHBondContact O-N 2.95Å; F52-D55 PolarHBondContact O-N 2.96Å; F52-G178 WeakPolarHBondContact CD2-O 3.05Å; F52-V181 HydrophobicContact CD2-CB 4.36Å; F52-V181 HydrophobicContact CD2-CG1 4.28Å; F52-V181 HydrophobicContact CE2-CB 4.29Å; F52-V181 HydrophobicContact CE2-CG1 3.83Å; F52-N182 HydrophobicContact CB-CB 4.44Å; F52-N182 HydrophobicContact CD1-CB 3.97Å; F52-N182 HydrophobicContact CD2-CB 3.72Å; F52-N182 HydrophobicContact CE1-CB 4.05Å; F52-N182 WeakPolarHBondContact CE1-OD1 3.24Å; F52-N182 VanDerWaalsContact CE2-CA 3.49Å; F52-N182 HydrophobicContact CE2-CB 3.84Å; F52-N182 HydrophobicContact CG-CB 3.79Å; F52-N182 HydrophobicContact CZ-CB 4Å; F52-N182 WeakPolarHBondContact O-CB 3.43Å; F52-N182 PolarHBondContact O-ND2 3.01Å; F52-N182 PolarHBondContact O-OD1 2.91Å; F52-M186 HydrophobicContact CE1-CG 4.03Å; F52-M186 HydrophobicContact CE1-SD 3.77Å; F52-M186 HydrophobicContact CZ-CG 4.04Å; F52-M186 HydrophobicContact CZ-SD 3.86Å; F52-A212 HydrophobicContact CD1-CB 4.39Å; F52-A212 HydrophobicContact CE1-CB 3.84Å; F52-T215 HydrophobicContact CD1-CG2 4.05Å; F52-T215 HydrophobicContact CD2-CG2 4.14Å; F52-T215 HydrophobicContact CE1-CG2 4.25Å; F52-T215 HydrophobicContact CE2-CG2 4.3Å; F52-T215 HydrophobicContact CG-CG2 4.02Å; F52-T215 HydrophobicContact CZ-CG2 4.37Å
53	C	97.4	Very high	94.6	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-78.4	-24.5	-173.3	-71.6	0	0	0	0	114.2	G49 S50 D55 N56 Q118 R137 F140 A212 T215 C216	G49-C53 VanDerWaalsContact O-CB 3.31Å; G49-C53 WeakPolarHBondContact O-CB 3.42Å; G49-C53 PolarHBondContact O-N 3.15Å; S50-C53 PolarHBondContact O-N 3.15Å; C53-D55 PolarHBondContact O-N 2.99Å; C53-N56 VanDerWaalsContact CA-ND2 3.32Å; C53-N56 WeakPolarHBondContact CA-ND2 3.34Å; C53-N56 WeakPolarHBondContact CB-ND2 3.29Å; C53-N56 WeakPolarHBondContact O-CB 3.3Å; C53-N56 PolarHBondContact O-N 2.93Å; C53-N56 PolarHBondContact O-ND2 3.29Å; C53-Q118 HydrophobicContact CB-CG 4.23Å; C53-R137 PolarHBondContact O-NH1 3.25Å; C53-F140 HydrophobicContact CB-CE2 3.61Å; C53-F140 HydrophobicContact CB-CZ 3.78Å; C53-A212 PolarHBondContact SG-O 3.28Å; C53-A212 VanDerWaalsContact SG-O 3.41Å; C53-T215 PolarHBondContact SG-OG1 3.29Å; C53-C216 PolarHBondContact SG-SG 2.65Å
54	Y	96.4	Very high	94.8	Very high	23 Å²	23	13.2 Å²	13.2	9%	0.09	6%	0.062	C	C	.	.	H	α-helix	trans	-53.9	-41.8	171.4	173.6	-101.8	0	0	0	111.1	S50 P57 Y79 Y82 R137	S50-Y54 VanDerWaalsContact O-CB 3.22Å; S50-Y54 WeakPolarHBondContact O-CB 3.5Å; S50-Y54 PolarHBondContact O-N 2.93Å; Y54-P57 WeakPolarHBondContact O-CD 3.36Å; Y54-Y79 HydrophobicContact CE1-CE1 4.4Å; Y54-Y79 HydrophobicContact CE2-CD1 4.48Å; Y54-Y82 AromaticContact CD2-CD1 3.97Å; Y54-Y82 HydrophobicContact CD2-CD1 3.97Å; Y54-Y82 AromaticContact CD2-CD2 3.93Å; Y54-Y82 HydrophobicContact CD2-CD2 3.93Å; Y54-Y82 AromaticContact CD2-CE1 3.78Å; Y54-Y82 HydrophobicContact CD2-CE1 3.78Å; Y54-Y82 AromaticContact CD2-CE2 3.72Å; Y54-Y82 HydrophobicContact CD2-CE2 3.72Å; Y54-Y82 HydrophobicContact CD2-CG 4.03Å; Y54-Y82 AromaticContact CD2-CZ 3.63Å; Y54-Y82 AromaticContact CE2-CD1 3.43Å; Y54-Y82 HydrophobicContact CE2-CD1 3.43Å; Y54-Y82 VanDerWaalsContact CE2-CD1 3.43Å; Y54-Y82 HydrophobicContact CE2-CD2 4.21Å; Y54-Y82 AromaticContact CE2-CE1 3.42Å; Y54-Y82 HydrophobicContact CE2-CE1 3.42Å; Y54-Y82 VanDerWaalsContact CE2-CE1 3.42Å; Y54-Y82 HydrophobicContact CE2-CE2 4.2Å; Y54-Y82 AromaticContact CE2-CG 3.83Å; Y54-Y82 HydrophobicContact CE2-CG 3.83Å; Y54-Y82 AromaticContact CE2-CZ 3.81Å; Y54-R137 PolarHBondContact O-NH1 2.94Å; Y54-R137 PolarHBondContact O-NH2 3.46Å
55	D	95.8	Very high	95	Very high	2 Å²	2	14.2 Å²	14.2	1%	0.011	7%	0.067	C	C	.	.	T	Hydrogen-bonded Turn	trans	-87.2	0.9	-176.6	-78.8	-47.8	0	0	0	114.3	F52 C53 A58 A59 S179 N182 M183 Y304	F52-D55 PolarHBondContact O-N 2.96Å; C53-D55 PolarHBondContact O-N 2.99Å; D55-A58 PolarHBondContact O-N 3.49Å; D55-A59 PolarHBondContact O-N 2.89Å; D55-A59 VanDerWaalsContact O-N 3.07Å; D55-S179 WeakPolarHBondContact OD2-CB 3.25Å; D55-S179 PolarHBondContact OD2-OG 3.14Å; D55-N182 WeakPolarHBondContact CB-ND2 3.48Å; D55-N182 PolarHBondContact O-ND2 3.2Å; D55-M183 HydrophobicContact CB-CE 3.6Å; D55-Y304 PolarHBondContact OD1-OH 3.42Å
56	N	96.8	Very high	95	Very high	0 Å²	0	17.4 Å²	17.4	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-50.9	-47.1	177.8	-82.7	-30.8	0	0	0	113	C53 A58 A59 L60 Q118 F121 N182 L209	C53-N56 VanDerWaalsContact CA-ND2 3.32Å; C53-N56 WeakPolarHBondContact CA-ND2 3.34Å; C53-N56 WeakPolarHBondContact CB-ND2 3.29Å; C53-N56 WeakPolarHBondContact O-CB 3.3Å; C53-N56 PolarHBondContact O-N 2.93Å; C53-N56 PolarHBondContact O-ND2 3.29Å; N56-A58 PolarHBondContact O-N 3.27Å; N56-A59 PolarHBondContact O-N 3.33Å; N56-L60 PolarHBondContact O-N 3.27Å; N56-L60 VanDerWaalsContact O-N 3.14Å; N56-Q118 PolarHBondContact ND2-NE2 2.8Å; N56-Q118 PolarHBondContact ND2-OE1 3.5Å; N56-F121 HydrophobicContact CB-CE1 4.28Å; N56-N182 PolarHBondContact N-ND2 2.92Å; N56-N182 PolarHBondContact OD1-OD1 3.38Å; N56-L209 HydrophobicContact CB-CD2 3.77Å
57	P	96.3	Very high	95.2	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-61.2	-42.8	-179	-25.3	37	0	0	0	113.1	Y54 L60 Q61 F75 L78 Y79 F121	Y54-P57 WeakPolarHBondContact O-CD 3.36Å; P57-L60 CarbonylContact O-C 3.54Å; P57-L60 VanDerWaalsContact O-C 3.32Å; P57-L60 PolarHBondContact O-N 3.05Å; P57-Q61 WeakPolarHBondContact O-CA 3.43Å; P57-Q61 PolarHBondContact O-N 3.43Å; P57-F75 HydrophobicContact CB-CE2 3.75Å; P57-F75 HydrophobicContact CB-CZ 3.85Å; P57-F75 WeakPolarHBondContact O-CE2 3.02Å; P57-F75 WeakPolarHBondContact O-CZ 3.46Å; P57-L78 HydrophobicContact CB-CD1 4.14Å; P57-L78 HydrophobicContact CG-CB 4.4Å; P57-L78 HydrophobicContact CG-CD1 4.23Å; P57-Y79 HydrophobicContact CB-CE2 3.97Å; P57-F121 HydrophobicContact CG-CE1 4.43Å; P57-F121 HydrophobicContact CG-CZ 3.94Å
58	A	94.8	Very high	95.4	Very high	0 Å²	0	19 Å²	19	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-66.5	-42.5	177.7	0	0	0	0	0	112.7	D55 N56 L60 Q61 Y79 M183 Q282	D55-A58 PolarHBondContact O-N 3.49Å; N56-A58 PolarHBondContact O-N 3.27Å; A58-L60 PolarHBondContact O-N 3.38Å; A58-Q61 WeakPolarHBondContact O-CB 3.48Å; A58-Q61 PolarHBondContact O-N 3.25Å; A58-Y79 WeakPolarHBondContact CB-OH 3.36Å; A58-Y79 PolarHBondContact N-OH 2.92Å; A58-M183 HydrophobicContact CB-CE 3.32Å; A58-M183 HydrophobicContact CB-SD 4.28Å; A58-Q282 PolarHBondContact O-OE1 3.3Å
59	A	94.3	Very high	95.5	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-65.9	-24.4	-179.7	0	0	0	0	0	113.3	D55 N56 N182 M183 M186 Q282 R297	D55-A59 PolarHBondContact O-N 2.89Å; D55-A59 VanDerWaalsContact O-N 3.07Å; N56-A59 PolarHBondContact O-N 3.33Å; A59-N182 VanDerWaalsContact CB-ND2 3.33Å; A59-N182 WeakPolarHBondContact CB-ND2 3.38Å; A59-M183 HydrophobicContact CB-CE 4.46Å; A59-M183 HydrophobicContact CB-SD 3.88Å; A59-M186 HydrophobicContact CB-CB 4.01Å; A59-Q282 PolarHBondContact O-OE1 3.34Å; A59-R297 WeakPolarHBondContact O-CD 3.38Å
60	L	95	Very high	95.6	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	13%	0.126	C	C	.	.	T	Hydrogen-bonded Turn	trans	-118	26.2	178.2	-65.9	179.5	0	0	0	112	N56 P57 A58 T62 Q63 V64 M186 Y190 L205 L209	N56-L60 PolarHBondContact O-N 3.27Å; N56-L60 VanDerWaalsContact O-N 3.14Å; P57-L60 CarbonylContact O-C 3.54Å; P57-L60 VanDerWaalsContact O-C 3.32Å; P57-L60 PolarHBondContact O-N 3.05Å; A58-L60 PolarHBondContact O-N 3.38Å; L60-T62 PolarHBondContact O-N 3.42Å; L60-Q63 HydrophobicContact CB-CB 4.34Å; L60-Q63 HydrophobicContact CD2-CG 4.45Å; L60-Q63 CarbonylContact O-C 3.59Å; L60-Q63 WeakPolarHBondContact O-CB 3.38Å; L60-Q63 PolarHBondContact O-N 3.48Å; L60-Q63 PolarHBondContact O-OE1 2.98Å; L60-V64 HydrophobicContact CB-CG2 4.24Å; L60-V64 WeakPolarHBondContact O-CG2 3.19Å; L60-V64 PolarHBondContact O-N 2.95Å; L60-M186 HydrophobicContact CD1-CB 4.42Å; L60-M186 HydrophobicContact CD1-CE 3.74Å; L60-M186 HydrophobicContact CD2-CB 4.15Å; L60-M186 HydrophobicContact CG-CB 4.07Å; L60-Y190 HydrophobicContact CD2-CD2 4.46Å; L60-Y190 HydrophobicContact CD2-CG 4.4Å; L60-L205 HydrophobicContact CB-CD1 4.45Å; L60-L205 HydrophobicContact CD1-CD1 3.92Å; L60-L209 HydrophobicContact CD1-CD2 4.11Å
61	Q	94.1	Very high	95.6	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-54.2	-50.9	-169.7	-179.9	-178.7	17.4	0	0	112.2	P57 A58 Q63 V64 I65 F75 G279 V283	P57-Q61 WeakPolarHBondContact O-CA 3.43Å; P57-Q61 PolarHBondContact O-N 3.43Å; A58-Q61 WeakPolarHBondContact O-CB 3.48Å; A58-Q61 PolarHBondContact O-N 3.25Å; Q61-Q63 VanDerWaalsContact C-N 3.31Å; Q61-Q63 PolarHBondContact O-N 2.88Å; Q61-V64 PolarHBondContact O-N 3.4Å; Q61-I65 HydrophobicContact CG-CD1 3.98Å; Q61-I65 WeakPolarHBondContact O-CB 3.31Å; Q61-I65 WeakPolarHBondContact O-CG1 3.43Å; Q61-I65 PolarHBondContact O-N 2.93Å; Q61-F75 HydrophobicContact CB-CE2 4.2Å; Q61-F75 HydrophobicContact CB-CZ 3.91Å; Q61-F75 HydrophobicContact CG-CD1 4.36Å; Q61-F75 HydrophobicContact CG-CD2 4.48Å; Q61-F75 HydrophobicContact CG-CE1 3.82Å; Q61-F75 HydrophobicContact CG-CE2 3.95Å; Q61-F75 HydrophobicContact CG-CZ 3.59Å; Q61-G279 PolarHBondContact OE1-O 3.23Å; Q61-V283 HydrophobicContact CB-CG2 4.45Å; Q61-V283 VanDerWaalsContact CD-CG2 3.41Å; Q61-V283 HydrophobicContact CG-CG2 3.8Å
62	T	92.5	Very high	95.6	Very high	26 Å²	26	26.3 Å²	26.3	16%	0.16	13%	0.134	C	C	.	.	H	α-helix	trans	-58.9	-42.9	178.6	-50.8	0	0	0	0	111.6	L60 Q66 Q282	L60-T62 PolarHBondContact O-N 3.42Å; T62-Q66 HydrophobicContact CG2-CG 4.48Å; T62-Q66 VanDerWaalsContact O-CB 3.3Å; T62-Q66 WeakPolarHBondContact O-CB 3.38Å; T62-Q66 WeakPolarHBondContact O-CG 3.37Å; T62-Q66 PolarHBondContact O-N 3.26Å; T62-Q282 PolarHBondContact OG1-NE2 3.14Å; T62-Q282 VanDerWaalsContact OG1-NE2 3.07Å
63	Q	95.1	Very high	95.5	Very high	30 Å²	30	26.7 Å²	26.7	14%	0.14	14%	0.14	C	C	.	.	H	α-helix	trans	-68.5	-43.3	-180	-67.9	71.8	16.9	0	0	111.4	L60 Q61 Q66 D67 Y190 L205	L60-Q63 HydrophobicContact CB-CB 4.34Å; L60-Q63 HydrophobicContact CD2-CG 4.45Å; L60-Q63 CarbonylContact O-C 3.59Å; L60-Q63 WeakPolarHBondContact O-CB 3.38Å; L60-Q63 PolarHBondContact O-N 3.48Å; L60-Q63 PolarHBondContact O-OE1 2.98Å; Q61-Q63 VanDerWaalsContact C-N 3.31Å; Q61-Q63 PolarHBondContact O-N 2.88Å; Q63-Q66 PolarHBondContact O-N 2.83Å; Q63-D67 WeakPolarHBondContact O-CA 3.37Å; Q63-D67 WeakPolarHBondContact O-CB 3.43Å; Q63-D67 PolarHBondContact O-N 3.48Å; Q63-Y190 HydrophobicContact CB-CD2 4.21Å; Q63-Y190 HydrophobicContact CB-CE2 3.87Å; Q63-Y190 HydrophobicContact CG-CD1 3.93Å; Q63-Y190 HydrophobicContact CG-CD2 3.93Å; Q63-Y190 HydrophobicContact CG-CE1 3.84Å; Q63-Y190 HydrophobicContact CG-CE2 3.78Å; Q63-Y190 HydrophobicContact CG-CG 4.01Å; Q63-L205 HydrophobicContact CB-CD1 4.48Å
64	V	96.4	Very high	95.5	Very high	1 Å²	1	30.4 Å²	30.4	1%	0.006	16%	0.157	C	C	.	.	H	α-helix	trans	-61.6	-47.5	177.7	174.8	0	0	0	0	110.4	L60 Q61 M68 L70 F75 L78 M133 L205	L60-V64 HydrophobicContact CB-CG2 4.24Å; L60-V64 WeakPolarHBondContact O-CG2 3.19Å; L60-V64 PolarHBondContact O-N 2.95Å; Q61-V64 PolarHBondContact O-N 3.4Å; V64-M68 VanDerWaalsContact O-CB 3.24Å; V64-M68 WeakPolarHBondContact O-CB 3.49Å; V64-M68 PolarHBondContact O-N 3.46Å; V64-M68 VanDerWaalsContact O-N 3.17Å; V64-L70 HydrophobicContact CG1-CD1 4.1Å; V64-F75 HydrophobicContact CB-CD2 4.18Å; V64-F75 HydrophobicContact CB-CE2 4.2Å; V64-F75 HydrophobicContact CG1-CD2 3.83Å; V64-F75 HydrophobicContact CG1-CE2 4.2Å; V64-L78 HydrophobicContact CG1-CD1 4.08Å; V64-M133 HydrophobicContact CG1-CE 4.33Å; V64-L205 HydrophobicContact CB-CD2 4.49Å; V64-L205 HydrophobicContact CG2-CD1 3.98Å; V64-L205 HydrophobicContact CG2-CD2 4.1Å
65	I	94.9	Very high	95.6	Very high	36 Å²	36	29.3 Å²	29.3	19%	0.185	15%	0.152	C	C	.	.	H	α-helix	trans	-61.1	-46.7	178.7	-72	175	0	0	0	110.9	Q61 N69 L70 F75	Q61-I65 HydrophobicContact CG-CD1 3.98Å; Q61-I65 WeakPolarHBondContact O-CB 3.31Å; Q61-I65 WeakPolarHBondContact O-CG1 3.43Å; Q61-I65 PolarHBondContact O-N 2.93Å; I65-N69 WeakPolarHBondContact O-CA 3.25Å; I65-N69 PolarHBondContact O-N 2.83Å; I65-N69 VanDerWaalsContact O-N 3.14Å; I65-L70 WeakPolarHBondContact CG2-O 3.36Å; I65-L70 PolarHBondContact O-N 2.79Å; I65-F75 HydrophobicContact CD1-CB 4.3Å; I65-F75 HydrophobicContact CD1-CG 4.28Å; I65-F75 HydrophobicContact CG1-CB 3.99Å; I65-F75 HydrophobicContact CG1-CD2 4.11Å; I65-F75 HydrophobicContact CG1-CG 4.14Å
66	Q	94.9	Very high	95.6	Very high	134 Å²	134	29.2 Å²	29.2	63%	0.626	15%	0.152	S	C	*	.	H	α-helix	trans	-74.5	-48.6	-176.5	-71.1	174.8	-11	0	0	112.9	T62 Q63 M68 N69	T62-Q66 HydrophobicContact CG2-CG 4.48Å; T62-Q66 VanDerWaalsContact O-CB 3.3Å; T62-Q66 WeakPolarHBondContact O-CB 3.38Å; T62-Q66 WeakPolarHBondContact O-CG 3.37Å; T62-Q66 PolarHBondContact O-N 3.26Å; Q63-Q66 PolarHBondContact O-N 2.83Å; Q66-M68 PolarHBondContact O-N 2.99Å; Q66-N69 PolarHBondContact O-N 3.13Å
67	D	96.1	Very high	95.7	Very high	25 Å²	25	31.3 Å²	31.3	13%	0.134	16%	0.162	C	C	.	.	H	α-helix	trans	-73.7	-28.6	-172.5	-68.3	-16.2	0	0	0	113	Q63 Y190 G201 L205	Q63-D67 WeakPolarHBondContact O-CA 3.37Å; Q63-D67 WeakPolarHBondContact O-CB 3.43Å; Q63-D67 PolarHBondContact O-N 3.48Å; D67-Y190 VanDerWaalsContact CG-OH 3.28Å; D67-Y190 PolarHBondContact OD1-OH 3.22Å; D67-Y190 WeakPolarHBondContact OD2-CE2 3.14Å; D67-Y190 VanDerWaalsContact OD2-CZ 3.22Å; D67-Y190 PolarHBondContact OD2-OH 3.41Å; D67-G201 VanDerWaalsContact CG-CA 3.47Å; D67-G201 WeakPolarHBondContact OD1-CA 3.34Å; D67-G201 PolarHBondContact OD1-N 2.92Å; D67-L205 HydrophobicContact CB-CB 4.46Å; D67-L205 HydrophobicContact CB-CD2 4.23Å
68	M	96.8	Very high	95.7	Very high	14 Å²	14	31.3 Å²	31.3	7%	0.069	16%	0.162	C	C	.	.	T	Hydrogen-bonded Turn	trans	-99.3	-0.3	176.2	-57.6	-66.4	-56.8	0	0	112.6	V64 Q66 L70 A125 F130 M133 H202 L205	V64-M68 VanDerWaalsContact O-CB 3.24Å; V64-M68 WeakPolarHBondContact O-CB 3.49Å; V64-M68 PolarHBondContact O-N 3.46Å; V64-M68 VanDerWaalsContact O-N 3.17Å; Q66-M68 PolarHBondContact O-N 2.99Å; M68-L70 HydrophobicContact CB-CD1 3.72Å; M68-L70 HydrophobicContact CB-CD2 4.28Å; M68-L70 HydrophobicContact CB-CG 3.69Å; M68-L70 HydrophobicContact CG-CD1 4.5Å; M68-A125 HydrophobicContact SD-CB 4.39Å; M68-F130 HydrophobicContact CE-CB 4.29Å; M68-M133 HydrophobicContact CE-SD 3.56Å; M68-M133 VanDerWaalsContact CE-SD 3.56Å; M68-M133 HydrophobicContact CG-SD 4Å; M68-M133 HydrophobicContact SD-SD 3.87Å; M68-H202 HydrophobicContact SD-CB 4Å; M68-L205 HydrophobicContact CG-CD2 3.84Å; M68-L205 HydrophobicContact SD-CD2 4.26Å
69	N	96	Very high	95.8	Very high	144 Å²	144	31.8 Å²	31.8	77%	0.77	16%	0.164	S	C	*	.	T	Hydrogen-bonded Turn	trans	51.7	56.1	-178.8	-172.4	60.8	0	0	0	113.3	I65 Q66	I65-N69 WeakPolarHBondContact O-CA 3.25Å; I65-N69 PolarHBondContact O-N 2.83Å; I65-N69 VanDerWaalsContact O-N 3.14Å; Q66-N69 PolarHBondContact O-N 3.13Å
70	L	96.2	Very high	96	Very high	22 Å²	22	31.8 Å²	31.8	12%	0.115	16%	0.164	C	C	.	.			trans	-107.2	159.5	-176.5	-55.3	172.6	0	0	0	111.4	V64 I65 M68 E74 F130	V64-L70 HydrophobicContact CG1-CD1 4.1Å; I65-L70 WeakPolarHBondContact CG2-O 3.36Å; I65-L70 PolarHBondContact O-N 2.79Å; M68-L70 HydrophobicContact CB-CD1 3.72Å; M68-L70 HydrophobicContact CB-CD2 4.28Å; M68-L70 HydrophobicContact CB-CG 3.69Å; M68-L70 HydrophobicContact CG-CD1 4.5Å; L70-E74 WeakPolarHBondContact CA-OE2 3.5Å; L70-E74 HydrophobicContact CB-CB 4.11Å; L70-E74 HydrophobicContact CD2-CB 4.21Å; L70-F130 HydrophobicContact CD1-CD2 3.47Å; L70-F130 VanDerWaalsContact CD1-CD2 3.47Å; L70-F130 HydrophobicContact CD1-CE2 3.41Å; L70-F130 VanDerWaalsContact CD1-CE2 3.41Å; L70-F130 HydrophobicContact CD1-CG 4.28Å; L70-F130 HydrophobicContact CD1-CZ 4.2Å; L70-F130 HydrophobicContact CD2-CB 4.27Å; L70-F130 HydrophobicContact CD2-CD1 4.27Å; L70-F130 HydrophobicContact CD2-CD2 3.92Å; L70-F130 HydrophobicContact CD2-CE2 4.36Å; L70-F130 HydrophobicContact CD2-CG 3.87Å; L70-F130 HydrophobicContact CG-CD2 4.34Å
71	N	95.6	Very high	96.1	Very high	69 Å²	69	36.1 Å²	36.1	37%	0.369	18%	0.18	S	C	.	.			trans	-91.3	-179.4	161.2	65.3	40.8	0	0	0	111.8	A73 E74 F75 D407	N71-A73 WeakPolarHBondContact OD1-CA 3.39Å; N71-A73 WeakPolarHBondContact OD1-CB 3.47Å; N71-A73 PolarHBondContact OD1-N 2.92Å; N71-A73 VanDerWaalsContact OD1-N 3.08Å; N71-E74 PolarHBondContact N-OE2 3.01Å; N71-E74 PolarHBondContact ND2-OE2 3.39Å; N71-E74 WeakPolarHBondContact OD1-CB 3.38Å; N71-E74 WeakPolarHBondContact OD1-CG 3.25Å; N71-E74 PolarHBondContact OD1-N 2.74Å; N71-E74 PolarHBondContact OD1-OE2 3.46Å; N71-F75 WeakPolarHBondContact O-CB 3.32Å; N71-F75 PolarHBondContact O-N 3.35Å; N71-D407 PolarHBondContact OD1-OD2 3.35Å
72	T	94.9	Very high	96.3	Very high	16 Å²	16	36.8 Å²	36.8	10%	0.098	18%	0.183	C	C	.	.	H	α-helix	trans	-70.9	-37.5	-178.4	-44.4	0	0	0	0	112	F75 M76 V406 D407	T72-F75 PolarHBondContact O-N 3.17Å; T72-M76 HydrophobicContact CG2-CG 4.42Å; T72-M76 WeakPolarHBondContact O-CG 3.34Å; T72-M76 PolarHBondContact O-N 3.33Å; T72-V406 HydrophobicContact CG2-CB 3.96Å; T72-V406 HydrophobicContact CG2-CG1 3.89Å; T72-V406 HydrophobicContact CG2-CG2 4.49Å; T72-D407 WeakPolarHBondContact CB-OD1 3.23Å; T72-D407 PolarHBondContact N-OD1 3.49Å; T72-D407 VanDerWaalsContact N-OD1 3.12Å; T72-D407 PolarHBondContact N-OD2 2.78Å; T72-D407 PolarHBondContact OG1-OD1 3.33Å
73	A	95.9	Very high	96.5	Very high	19 Å²	19	35.6 Å²	35.6	16%	0.157	18%	0.175	C	C	.	.	H	α-helix	trans	-59.9	-44	176.6	0	0	0	0	0	112.5	N71 M76 Q77 V404 D407	N71-A73 WeakPolarHBondContact OD1-CA 3.39Å; N71-A73 WeakPolarHBondContact OD1-CB 3.47Å; N71-A73 PolarHBondContact OD1-N 2.92Å; N71-A73 VanDerWaalsContact OD1-N 3.08Å; A73-M76 PolarHBondContact O-N 3.04Å; A73-Q77 PolarHBondContact O-N 2.77Å; A73-V404 HydrophobicContact CB-CG2 4.16Å; A73-D407 WeakPolarHBondContact CB-OD2 3.45Å; A73-D407 PolarHBondContact N-OD2 3.47Å
74	E	97	Very high	96.5	Very high	77 Å²	77	38.5 Å²	38.5	36%	0.36	19%	0.185	S	C	.	.	H	α-helix	trans	-64.9	-48.8	174.3	-71	168.5	148.3	0	0	110.5	L70 N71 M76 Q77 F130	L70-E74 WeakPolarHBondContact CA-OE2 3.5Å; L70-E74 HydrophobicContact CB-CB 4.11Å; L70-E74 HydrophobicContact CD2-CB 4.21Å; N71-E74 PolarHBondContact N-OE2 3.01Å; N71-E74 PolarHBondContact ND2-OE2 3.39Å; N71-E74 WeakPolarHBondContact OD1-CB 3.38Å; N71-E74 WeakPolarHBondContact OD1-CG 3.25Å; N71-E74 PolarHBondContact OD1-N 2.74Å; N71-E74 PolarHBondContact OD1-OE2 3.46Å; E74-M76 VanDerWaalsContact C-N 3.26Å; E74-M76 PolarHBondContact O-N 3.46Å; E74-Q77 VanDerWaalsContact O-CB 3.23Å; E74-Q77 WeakPolarHBondContact O-CB 3.43Å; E74-Q77 PolarHBondContact O-N 2.9Å; E74-F130 HydrophobicContact CB-CE1 4.4Å; E74-F130 WeakPolarHBondContact O-CZ 3.33Å
75	F	97.4	Very high	96.5	Very high	0 Å²	0	39 Å²	39	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-53.3	-44	176.1	171	-96.5	0	0	0	112.4	P57 Q61 V64 I65 N71 T72 Q77 L78 Y79	P57-F75 HydrophobicContact CB-CE2 3.75Å; P57-F75 HydrophobicContact CB-CZ 3.85Å; P57-F75 WeakPolarHBondContact O-CE2 3.02Å; P57-F75 WeakPolarHBondContact O-CZ 3.46Å; Q61-F75 HydrophobicContact CB-CE2 4.2Å; Q61-F75 HydrophobicContact CB-CZ 3.91Å; Q61-F75 HydrophobicContact CG-CD1 4.36Å; Q61-F75 HydrophobicContact CG-CD2 4.48Å; Q61-F75 HydrophobicContact CG-CE1 3.82Å; Q61-F75 HydrophobicContact CG-CE2 3.95Å; Q61-F75 HydrophobicContact CG-CZ 3.59Å; V64-F75 HydrophobicContact CB-CD2 4.18Å; V64-F75 HydrophobicContact CB-CE2 4.2Å; V64-F75 HydrophobicContact CG1-CD2 3.83Å; V64-F75 HydrophobicContact CG1-CE2 4.2Å; I65-F75 HydrophobicContact CD1-CB 4.3Å; I65-F75 HydrophobicContact CD1-CG 4.28Å; I65-F75 HydrophobicContact CG1-CB 3.99Å; I65-F75 HydrophobicContact CG1-CD2 4.11Å; I65-F75 HydrophobicContact CG1-CG 4.14Å; N71-F75 WeakPolarHBondContact O-CB 3.32Å; N71-F75 PolarHBondContact O-N 3.35Å; T72-F75 PolarHBondContact O-N 3.17Å; F75-Q77 PolarHBondContact O-N 3.26Å; F75-L78 HydrophobicContact CD2-CD1 4.41Å; F75-L78 WeakPolarHBondContact O-CB 3.34Å; F75-L78 WeakPolarHBondContact O-CG 3.45Å; F75-L78 PolarHBondContact O-N 3.47Å; F75-L78 VanDerWaalsContact O-N 3.12Å; F75-Y79 AromaticContact CE1-CE2 3.99Å; F75-Y79 HydrophobicContact CE1-CE2 3.99Å; F75-Y79 HydrophobicContact CZ-CE2 4.03Å
76	M	97.1	Very high	96.4	Very high	0 Å²	0	37.2 Å²	37.2	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-70.2	-15.9	-179.3	-69.6	-60.3	-91.1	0	0	113.8	T72 A73 E74 L78 Y79 A80 P276 Q280 A399 V402	T72-M76 HydrophobicContact CG2-CG 4.42Å; T72-M76 WeakPolarHBondContact O-CG 3.34Å; T72-M76 PolarHBondContact O-N 3.33Å; A73-M76 PolarHBondContact O-N 3.04Å; E74-M76 VanDerWaalsContact C-N 3.26Å; E74-M76 PolarHBondContact O-N 3.46Å; M76-L78 PolarHBondContact O-N 3.16Å; M76-Y79 PolarHBondContact O-N 3.24Å; M76-Y79 VanDerWaalsContact O-N 3.11Å; M76-Y79 HydrophobicContact SD-CD2 4.01Å; M76-Y79 HydrophobicContact SD-CE2 4.47Å; M76-A80 PolarHBondContact O-N 3.19Å; M76-P276 HydrophobicContact CE-CB 3.93Å; M76-Q280 HydrophobicContact CE-CG 3.73Å; M76-Q280 HydrophobicContact SD-CG 3.77Å; M76-Q280 PolarHBondContact SD-OE1 3.04Å; M76-A399 VanDerWaalsContact CB-O 3.22Å; M76-A399 WeakPolarHBondContact CB-O 3.38Å; M76-A399 HydrophobicContact CE-CB 4.41Å; M76-V402 HydrophobicContact CE-CB 3.96Å; M76-V402 HydrophobicContact CE-CG1 3.52Å
77	Q	97.6	Very high	96.3	Very high	45 Å²	45	32.3 Å²	32.3	21%	0.21	16%	0.158	C	C	.	.	H	α-helix	trans	-60.6	-29.1	169.7	-63	-59.2	-28	0	0	112.1	A73 E74 F75 Y79 A80 W81 F130 E134	A73-Q77 PolarHBondContact O-N 2.77Å; E74-Q77 VanDerWaalsContact O-CB 3.23Å; E74-Q77 WeakPolarHBondContact O-CB 3.43Å; E74-Q77 PolarHBondContact O-N 2.9Å; F75-Q77 PolarHBondContact O-N 3.26Å; Q77-Y79 PolarHBondContact O-N 3.12Å; Q77-A80 PolarHBondContact O-N 3.36Å; Q77-A80 VanDerWaalsContact O-N 3.12Å; Q77-W81 WeakPolarHBondContact O-CB 3.34Å; Q77-W81 VanDerWaalsContact O-CD1 3.23Å; Q77-W81 PolarHBondContact O-N 3.37Å; Q77-F130 HydrophobicContact CB-CZ 4.46Å; Q77-E134 WeakPolarHBondContact CB-OE1 3.29Å
78	L	97.9	Very high	96	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-61.4	-28.8	176.6	-63.1	179	0	0	0	112.8	P57 V64 F75 M76 F121 F130 M133 E134 R137	P57-L78 HydrophobicContact CB-CD1 4.14Å; P57-L78 HydrophobicContact CG-CB 4.4Å; P57-L78 HydrophobicContact CG-CD1 4.23Å; V64-L78 HydrophobicContact CG1-CD1 4.08Å; F75-L78 HydrophobicContact CD2-CD1 4.41Å; F75-L78 WeakPolarHBondContact O-CB 3.34Å; F75-L78 WeakPolarHBondContact O-CG 3.45Å; F75-L78 PolarHBondContact O-N 3.47Å; F75-L78 VanDerWaalsContact O-N 3.12Å; M76-L78 PolarHBondContact O-N 3.16Å; L78-F121 HydrophobicContact CD1-CE2 3.98Å; L78-F121 HydrophobicContact CD1-CZ 4.2Å; L78-F121 HydrophobicContact CD2-CE2 3.84Å; L78-F121 HydrophobicContact CG-CE2 4.47Å; L78-F130 HydrophobicContact CD1-CE2 4.15Å; L78-F130 HydrophobicContact CD2-CE2 3.59Å; L78-F130 HydrophobicContact CD2-CZ 3.86Å; L78-F130 HydrophobicContact CG-CE2 3.82Å; L78-F130 HydrophobicContact CG-CZ 4Å; L78-M133 HydrophobicContact CD1-CE 4.35Å; L78-M133 HydrophobicContact CD2-CB 3.99Å; L78-E134 HydrophobicContact CD2-CG 4.32Å; L78-R137 HydrophobicContact CB-CG 4.19Å; L78-R137 HydrophobicContact CD2-CG 3.99Å; L78-R137 WeakPolarHBondContact O-CG 3.43Å; L78-R137 PolarHBondContact O-NE 3.38Å
79	Y	97.1	Very high	95.5	Very high	9 Å²	9	36.2 Å²	36.2	4%	0.035	18%	0.182	C	C	.	.	H	α-helix	trans	-82.7	-40.1	173	-73	-82.7	0	0	0	111.4	Y54 P57 A58 F75 M76 Q77 W81 Y82 S83	Y54-Y79 HydrophobicContact CE1-CE1 4.4Å; Y54-Y79 HydrophobicContact CE2-CD1 4.48Å; P57-Y79 HydrophobicContact CB-CE2 3.97Å; A58-Y79 WeakPolarHBondContact CB-OH 3.36Å; A58-Y79 PolarHBondContact N-OH 2.92Å; F75-Y79 AromaticContact CE1-CE2 3.99Å; F75-Y79 HydrophobicContact CE1-CE2 3.99Å; F75-Y79 HydrophobicContact CZ-CE2 4.03Å; M76-Y79 PolarHBondContact O-N 3.24Å; M76-Y79 VanDerWaalsContact O-N 3.11Å; M76-Y79 HydrophobicContact SD-CD2 4.01Å; M76-Y79 HydrophobicContact SD-CE2 4.47Å; Q77-Y79 PolarHBondContact O-N 3.12Å; Y79-W81 PolarHBondContact O-N 2.89Å; Y79-Y82 WeakPolarHBondContact O-CB 3.36Å; Y79-Y82 PolarHBondContact O-N 3.08Å; Y79-S83 PolarHBondContact O-N 3.29Å
80	A	97.3	Very high	95	Very high	0 Å²	0	30 Å²	30	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-60.7	-46.7	177.7	0	0	0	0	0	112.4	M76 Q77 Y82 S83 W84 A399 I400	M76-A80 PolarHBondContact O-N 3.19Å; Q77-A80 PolarHBondContact O-N 3.36Å; Q77-A80 VanDerWaalsContact O-N 3.12Å; A80-Y82 VanDerWaalsContact C-N 3.27Å; A80-Y82 PolarHBondContact O-N 2.92Å; A80-S83 PolarHBondContact O-N 3.42Å; A80-W84 PolarHBondContact O-N 3.36Å; A80-A399 HydrophobicContact CB-CB 4.39Å; A80-I400 HydrophobicContact CB-CD1 4.2Å; A80-I400 HydrophobicContact CB-CG1 3.86Å
81	W	97.9	Very high	94.2	Very high	92 Å²	92	30.4 Å²	30.4	35%	0.348	15%	0.151	S	C	.	.	H	α-helix	trans	-63.8	-28.7	178.8	-80	113.4	0	0	0	114	Q77 Y79 P85 E134 R137 F138	Q77-W81 WeakPolarHBondContact O-CB 3.34Å; Q77-W81 VanDerWaalsContact O-CD1 3.23Å; Q77-W81 PolarHBondContact O-N 3.37Å; Y79-W81 PolarHBondContact O-N 2.89Å; W81-P85 VanDerWaalsContact O-CD 3.25Å; W81-P85 WeakPolarHBondContact O-CD 3.49Å; W81-E134 VanDerWaalsContact CD1-OE1 3.3Å; W81-E134 HydrophobicContact CD2-CB 4.49Å; W81-E134 HydrophobicContact CG-CB 3.99Å; W81-E134 HydrophobicContact CG-CG 4.44Å; W81-E134 VanDerWaalsContact NE1-CD 3.31Å; W81-E134 PolarHBondContact NE1-OE1 2.98Å; W81-R137 HydrophobicContact CB-CB 4.14Å; W81-F138 HydrophobicContact CE3-CB 4.22Å; W81-F138 AromaticContact CE3-CD2 3.8Å; W81-F138 HydrophobicContact CE3-CD2 3.8Å; W81-F138 HydrophobicContact CE3-CG 4.36Å; W81-F138 HydrophobicContact CZ3-CD2 4.09Å; W81-F138 VanDerWaalsContact O-CA 3.27Å; W81-F138 WeakPolarHBondContact O-CA 3.5Å
82	Y	97.4	Very high	93.5	Very high	13 Å²	13	30.6 Å²	30.6	5%	0.051	15%	0.151	C	C	.	.	H	α-helix	trans	-66.9	-41.3	170.3	171.3	-87.6	0	0	0	112	Y54 Y79 A80 P85 N86 R137 F140 G141	Y54-Y82 AromaticContact CD2-CD1 3.97Å; Y54-Y82 HydrophobicContact CD2-CD1 3.97Å; Y54-Y82 AromaticContact CD2-CD2 3.93Å; Y54-Y82 HydrophobicContact CD2-CD2 3.93Å; Y54-Y82 AromaticContact CD2-CE1 3.78Å; Y54-Y82 HydrophobicContact CD2-CE1 3.78Å; Y54-Y82 AromaticContact CD2-CE2 3.72Å; Y54-Y82 HydrophobicContact CD2-CE2 3.72Å; Y54-Y82 HydrophobicContact CD2-CG 4.03Å; Y54-Y82 AromaticContact CD2-CZ 3.63Å; Y54-Y82 AromaticContact CE2-CD1 3.43Å; Y54-Y82 HydrophobicContact CE2-CD1 3.43Å; Y54-Y82 VanDerWaalsContact CE2-CD1 3.43Å; Y54-Y82 HydrophobicContact CE2-CD2 4.21Å; Y54-Y82 AromaticContact CE2-CE1 3.42Å; Y54-Y82 HydrophobicContact CE2-CE1 3.42Å; Y54-Y82 VanDerWaalsContact CE2-CE1 3.42Å; Y54-Y82 HydrophobicContact CE2-CE2 4.2Å; Y54-Y82 AromaticContact CE2-CG 3.83Å; Y54-Y82 HydrophobicContact CE2-CG 3.83Å; Y54-Y82 AromaticContact CE2-CZ 3.81Å; Y79-Y82 WeakPolarHBondContact O-CB 3.36Å; Y79-Y82 PolarHBondContact O-N 3.08Å; A80-Y82 VanDerWaalsContact C-N 3.27Å; A80-Y82 PolarHBondContact O-N 2.92Å; Y82-P85 WeakPolarHBondContact O-CD 3.5Å; Y82-P85 WeakPolarHBondContact O-CG 3.42Å; Y82-N86 PolarHBondContact O-ND2 3.22Å; Y82-R137 WeakPolarHBondContact CA-O 3.4Å; Y82-F140 AromaticContact CD2-CD1 3.61Å; Y82-F140 HydrophobicContact CD2-CD1 3.61Å; Y82-F140 HydrophobicContact CD2-CE1 4.18Å; Y82-F140 AromaticContact CE2-CD1 3.47Å; Y82-F140 HydrophobicContact CE2-CD1 3.47Å; Y82-F140 VanDerWaalsContact CE2-CD1 3.47Å; Y82-F140 AromaticContact CE2-CE1 3.71Å; Y82-F140 HydrophobicContact CE2-CE1 3.71Å; Y82-G141 WeakPolarHBondContact O-CA 3.48Å
83	S	96.6	Very high	92.5	Very high	1 Å²	1	29.9 Å²	29.9	1%	0.007	15%	0.147	C	C	.	.	H	α-helix	trans	-82.1	-29.5	-173	-71.9	0	0	0	0	114.3	Y79 A80 N86 V87 N392	Y79-S83 PolarHBondContact O-N 3.29Å; A80-S83 PolarHBondContact O-N 3.42Å; S83-N86 WeakPolarHBondContact O-CB 3.47Å; S83-N86 PolarHBondContact O-N 3.01Å; S83-N86 VanDerWaalsContact O-N 3.08Å; S83-V87 PolarHBondContact O-N 3.18Å; S83-N392 WeakPolarHBondContact CB-O 3.49Å; S83-N392 WeakPolarHBondContact CB-OD1 3.4Å; S83-N392 PolarHBondContact OG-OD1 3.34Å
84	W	96.2	Very high	91.5	Very high	92 Å²	92	29.8 Å²	29.8	35%	0.348	15%	0.148	S	C	.	.	T	Hydrogen-bonded Turn	trans	-50.2	-50.3	178.2	-80.4	124.4	0	0	0	116	A80 N86 V87 L393 A396 V397	A80-W84 PolarHBondContact O-N 3.36Å; W84-N86 PolarHBondContact O-N 3.05Å; W84-V87 HydrophobicContact CE3-CG2 4.18Å; W84-V87 WeakPolarHBondContact O-CB 3.5Å; W84-V87 WeakPolarHBondContact O-CG2 3.47Å; W84-V87 PolarHBondContact O-N 3.23Å; W84-L393 HydrophobicContact CH2-CD1 4.25Å; W84-L393 HydrophobicContact CZ3-CD1 3.84Å; W84-A396 HydrophobicContact CD2-CB 3.97Å; W84-A396 HydrophobicContact CE3-CB 4.35Å; W84-A396 HydrophobicContact CG-CB 4.36Å; W84-A396 HydrophobicContact CZ2-CB 4.16Å; W84-V397 HydrophobicContact CH2-CG2 4.43Å
85	P	94.9	Very high	90.5	Very high	10 Å²	10	29.9 Å²	29.9	7%	0.065	15%	0.147	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.7	-30.6	179.7	25	-34.9	0	0	0	112.1	W81 Y82 V87 V88 L89 F138 I142	W81-P85 VanDerWaalsContact O-CD 3.25Å; W81-P85 WeakPolarHBondContact O-CD 3.49Å; Y82-P85 WeakPolarHBondContact O-CD 3.5Å; Y82-P85 WeakPolarHBondContact O-CG 3.42Å; P85-V87 VanDerWaalsContact C-N 3.31Å; P85-V87 PolarHBondContact O-N 3.02Å; P85-V88 PolarHBondContact O-N 3.29Å; P85-L89 HydrophobicContact CB-CD1 4.07Å; P85-L89 WeakPolarHBondContact O-CB 3.39Å; P85-L89 WeakPolarHBondContact O-CG 3.4Å; P85-L89 PolarHBondContact O-N 3.32Å; P85-F138 HydrophobicContact CB-CD2 4.27Å; P85-F138 HydrophobicContact CB-CE2 3.89Å; P85-F138 HydrophobicContact CB-CZ 4.17Å; P85-F138 HydrophobicContact CG-CD2 4.04Å; P85-F138 HydrophobicContact CG-CE2 4.16Å; P85-I142 HydrophobicContact CB-CG1 3.73Å; P85-I142 HydrophobicContact CG-CG1 4.3Å
86	N	93.6	Very high	89.8	Confident	0 Å²	0	31.8 Å²	31.8	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-75.5	-17.6	-177.3	-65.2	-44.9	0	0	0	113.7	Y82 S83 W84 V88 C90 G141 E145 N392	Y82-N86 PolarHBondContact O-ND2 3.22Å; S83-N86 WeakPolarHBondContact O-CB 3.47Å; S83-N86 PolarHBondContact O-N 3.01Å; S83-N86 VanDerWaalsContact O-N 3.08Å; W84-N86 PolarHBondContact O-N 3.05Å; N86-V88 PolarHBondContact O-N 3.45Å; N86-C90 VanDerWaalsContact O-CB 3.29Å; N86-C90 WeakPolarHBondContact O-CB 3.47Å; N86-C90 PolarHBondContact O-N 3.26Å; N86-C90 PolarHBondContact O-SG 3.41Å; N86-G141 PolarHBondContact ND2-O 3.32Å; N86-G141 PolarHBondContact OD1-O 3.04Å; N86-E145 HydrophobicContact CB-CG 3.86Å; N86-E145 VanDerWaalsContact ND2-CG 3.32Å; N86-E145 WeakPolarHBondContact ND2-CG 3.47Å; N86-E145 WeakPolarHBondContact OD1-CB 3.34Å; N86-E145 WeakPolarHBondContact OD1-CG 3.47Å; N86-N392 HydrophobicContact CB-CB 3.88Å; N86-N392 VanDerWaalsContact CB-CG 3.43Å
87	V	92.9	Very high	89	Confident	30 Å²	30	31.8 Å²	31.8	18%	0.182	16%	0.157	C	C	.	.	H	α-helix	trans	-58	-31.7	170.5	-179	0	0	0	0	111.7	S83 W84 P85 F91 S389 N392 L393	S83-V87 PolarHBondContact O-N 3.18Å; W84-V87 HydrophobicContact CE3-CG2 4.18Å; W84-V87 WeakPolarHBondContact O-CB 3.5Å; W84-V87 WeakPolarHBondContact O-CG2 3.47Å; W84-V87 PolarHBondContact O-N 3.23Å; P85-V87 VanDerWaalsContact C-N 3.31Å; P85-V87 PolarHBondContact O-N 3.02Å; V87-F91 WeakPolarHBondContact O-CE2 3.42Å; V87-S389 WeakPolarHBondContact O-CB 3.33Å; V87-S389 PolarHBondContact O-OG 2.73Å; V87-N392 HydrophobicContact CG2-CB 4.47Å; V87-L393 HydrophobicContact CG1-CB 4.25Å; V87-L393 HydrophobicContact CG1-CD1 4.4Å; V87-L393 HydrophobicContact CG2-CB 3.94Å; V87-L393 HydrophobicContact CG2-CD1 4.28Å
88	V	88.8	Confident	87.8	Confident	89 Å²	89	31 Å²	31	54%	0.539	15%	0.154	S	C	.	.	H	α-helix	trans	-106	-42.8	179.5	-178.3	0	0	0	0	110.9	P85 N86 C90 F91 L92	P85-V88 PolarHBondContact O-N 3.29Å; N86-V88 PolarHBondContact O-N 3.45Å; V88-C90 VanDerWaalsContact C-N 3.31Å; V88-C90 PolarHBondContact O-N 3.36Å; V88-F91 WeakPolarHBondContact O-CB 3.42Å; V88-F91 PolarHBondContact O-N 3.08Å; V88-L92 HydrophobicContact CG1-CD1 4.26Å
89	L	87.5	Confident	86.8	Confident	32 Å²	32	36.3 Å²	36.3	17%	0.168	17%	0.174	C	C	.	.	H	α-helix	trans	-69.8	-24.7	-173.1	-72.3	174.2	0	0	0	113.8	P85 F91 L92 G93 I142	P85-L89 HydrophobicContact CB-CD1 4.07Å; P85-L89 WeakPolarHBondContact O-CB 3.39Å; P85-L89 WeakPolarHBondContact O-CG 3.4Å; P85-L89 PolarHBondContact O-N 3.32Å; L89-F91 PolarHBondContact O-N 3.41Å; L89-L92 CarbonylContact O-C 3.56Å; L89-L92 PolarHBondContact O-N 3.01Å; L89-G93 PolarHBondContact O-N 3.39Å; L89-I142 HydrophobicContact CD1-CB 3.85Å; L89-I142 HydrophobicContact CD1-CG1 3.82Å; L89-I142 HydrophobicContact CD1-CG2 3.7Å
90	C	84.2	Confident	86.1	Confident	13 Å²	13	39.8 Å²	39.8	9%	0.088	20%	0.196	C	C	.	.	H	α-helix	trans	-63.5	-23.1	174.6	-72.3	0	0	0	0	112.7	N86 V88 G385 Q388 S389	N86-C90 VanDerWaalsContact O-CB 3.29Å; N86-C90 WeakPolarHBondContact O-CB 3.47Å; N86-C90 PolarHBondContact O-N 3.26Å; N86-C90 PolarHBondContact O-SG 3.41Å; V88-C90 VanDerWaalsContact C-N 3.31Å; V88-C90 PolarHBondContact O-N 3.36Å; C90-G385 WeakPolarHBondContact O-CA 3.35Å; C90-Q388 HydrophobicContact CB-CB 4.03Å; C90-Q388 HydrophobicContact CB-CG 4.26Å; C90-Q388 VanDerWaalsContact SG-CG 3.51Å; C90-S389 VanDerWaalsContact CB-OG 3.26Å; C90-S389 WeakPolarHBondContact CB-OG 3.28Å
91	F	79.3	Confident	85.5	Confident	32 Å²	32	43.4 Å²	43.4	14%	0.14	21%	0.212	C	C	.	.	H	α-helix	trans	-78.2	-23	169.3	-65.1	-74.7	0	0	0	113.8	V87 V88 L89 I248 L250 F386 S389	V87-F91 WeakPolarHBondContact O-CE2 3.42Å; V88-F91 WeakPolarHBondContact O-CB 3.42Å; V88-F91 PolarHBondContact O-N 3.08Å; L89-F91 PolarHBondContact O-N 3.41Å; F91-I248 WeakPolarHBondContact O-CD1 3.48Å; F91-L250 HydrophobicContact CD1-CD2 3.88Å; F91-L250 HydrophobicContact CE1-CD2 4.14Å; F91-L250 HydrophobicContact CG-CD2 4.19Å; F91-F386 VanDerWaalsContact CE1-CA 3.47Å; F91-F386 HydrophobicContact CE1-CB 3.75Å; F91-F386 AromaticContact CE1-CD2 3.71Å; F91-F386 HydrophobicContact CE1-CD2 3.71Å; F91-F386 HydrophobicContact CE1-CG 4.17Å; F91-F386 HydrophobicContact CZ-CB 4.15Å; F91-F386 AromaticContact CZ-CD2 3.56Å; F91-F386 HydrophobicContact CZ-CD2 3.56Å; F91-F386 HydrophobicContact CZ-CE2 4.3Å; F91-F386 HydrophobicContact CZ-CG 4.17Å; F91-S389 WeakPolarHBondContact CD2-OG 3.29Å; F91-S389 WeakPolarHBondContact CE2-OG 3.14Å
92	L	81.3	Confident	84.9	Confident	73 Å²	73	39.8 Å²	39.8	38%	0.382	20%	0.204	S	C	.	.	H	α-helix	trans	-108.3	-22.2	-170.5	-59.2	-180	0	0	0	112.7	V88 L89 G94 F95 L96	V88-L92 HydrophobicContact CG1-CD1 4.26Å; L89-L92 CarbonylContact O-C 3.56Å; L89-L92 PolarHBondContact O-N 3.01Å; L92-G94 PolarHBondContact O-N 3.33Å; L92-F95 CarbonylContact O-C 3.54Å; L92-F95 WeakPolarHBondContact O-CB 3.35Å; L92-F95 PolarHBondContact O-N 3.42Å; L92-F95 VanDerWaalsContact O-N 3.13Å; L92-L96 HydrophobicContact CB-CD1 4.42Å; L92-L96 WeakPolarHBondContact O-CB 3.4Å; L92-L96 VanDerWaalsContact O-CG 3.26Å; L92-L96 WeakPolarHBondContact O-CG 3.46Å; L92-L96 PolarHBondContact O-N 2.92Å
93	G	75.3	Confident	84.3	Confident	1 Å²	1	40 Å²	40	1%	0.01	21%	0.205	C	C	.	.	H	α-helix	trans	-57.6	-49.8	-172.5	0	0	0	0	0	112.6	L89 L96 I97	L89-G93 PolarHBondContact O-N 3.39Å; G93-L96 PolarHBondContact O-N 3.14Å; G93-I97 VanDerWaalsContact O-CG1 3.32Å; G93-I97 WeakPolarHBondContact O-CG1 3.45Å; G93-I97 PolarHBondContact O-N 3.13Å; G93-I97 VanDerWaalsContact O-N 3.11Å
94	G	73.4	Confident	84	Confident	16 Å²	16	41.7 Å²	41.7	17%	0.165	21%	0.212	C	C	.	.	H	α-helix	trans	-61.4	-45.9	174.5	0	0	0	0	0	112.3	L92 L96 I97 D98	L92-G94 PolarHBondContact O-N 3.33Å; G94-L96 PolarHBondContact O-N 3.11Å; G94-I97 PolarHBondContact O-N 3.22Å; G94-I97 VanDerWaalsContact O-N 3.16Å; G94-D98 WeakPolarHBondContact O-CB 3.36Å; G94-D98 PolarHBondContact O-N 3.07Å
95	F	77.7	Confident	83.8	Confident	80 Å²	80	41.6 Å²	41.6	35%	0.351	22%	0.218	S	C	.	.	H	α-helix	trans	-59.1	-43.8	176.9	172.7	-94.2	0	0	0	113	L92 I97 D98 R99 V100 I248	L92-F95 CarbonylContact O-C 3.54Å; L92-F95 WeakPolarHBondContact O-CB 3.35Å; L92-F95 PolarHBondContact O-N 3.42Å; L92-F95 VanDerWaalsContact O-N 3.13Å; F95-I97 VanDerWaalsContact C-N 3.29Å; F95-I97 PolarHBondContact O-N 3.24Å; F95-D98 PolarHBondContact O-N 3.21Å; F95-R99 HydrophobicContact CD2-CB 4.21Å; F95-R99 HydrophobicContact CD2-CG 3.9Å; F95-R99 HydrophobicContact CE2-CB 3.92Å; F95-R99 HydrophobicContact CE2-CG 3.79Å; F95-R99 HydrophobicContact CZ-CB 4.18Å; F95-R99 WeakPolarHBondContact O-CB 3.26Å; F95-R99 PolarHBondContact O-N 3.29Å; F95-V100 HydrophobicContact CD1-CG2 4.37Å; F95-V100 HydrophobicContact CE1-CG2 3.86Å; F95-V100 HydrophobicContact CZ-CG2 4.49Å; F95-I248 HydrophobicContact CB-CD1 4.39Å
96	L	81	Confident	83.7	Confident	39 Å²	39	41.1 Å²	41.1	20%	0.204	22%	0.215	C	C	.	.	I	π-helix	trans	-62.1	-39.1	177.9	-71.8	174.7	0	0	0	111.2	L92 G93 G94 V100 F101 F110	L92-L96 HydrophobicContact CB-CD1 4.42Å; L92-L96 WeakPolarHBondContact O-CB 3.4Å; L92-L96 VanDerWaalsContact O-CG 3.26Å; L92-L96 WeakPolarHBondContact O-CG 3.46Å; L92-L96 PolarHBondContact O-N 2.92Å; G93-L96 PolarHBondContact O-N 3.14Å; G94-L96 PolarHBondContact O-N 3.11Å; L96-V100 HydrophobicContact CD2-CB 4.34Å; L96-V100 HydrophobicContact CD2-CG2 4.03Å; L96-V100 WeakPolarHBondContact O-CB 3.44Å; L96-V100 PolarHBondContact O-N 2.89Å; L96-F101 HydrophobicContact CB-CD2 3.99Å; L96-F101 HydrophobicContact CB-CE2 3.96Å; L96-F101 HydrophobicContact CD1-CE2 4.4Å; L96-F101 HydrophobicContact CD2-CE2 3.91Å; L96-F101 HydrophobicContact CD2-CZ 4.48Å; L96-F101 HydrophobicContact CG-CE2 4.3Å; L96-F101 WeakPolarHBondContact O-CD2 3.48Å; L96-F101 PolarHBondContact O-N 2.84Å; L96-F110 HydrophobicContact CB-CZ 4.3Å; L96-F110 HydrophobicContact CD1-CZ 4.3Å
97	I	80.3	Confident	83.6	Confident	1 Å²	1	41.1 Å²	41.1	1%	0.005	22%	0.215	C	C	.	.	I	π-helix	trans	-68.4	-49.7	176	-68.3	166.2	0	0	0	110.7	G93 G94 F95 G102 I103 F110 V149 A150	G93-I97 VanDerWaalsContact O-CG1 3.32Å; G93-I97 WeakPolarHBondContact O-CG1 3.45Å; G93-I97 PolarHBondContact O-N 3.13Å; G93-I97 VanDerWaalsContact O-N 3.11Å; G94-I97 PolarHBondContact O-N 3.22Å; G94-I97 VanDerWaalsContact O-N 3.16Å; F95-I97 VanDerWaalsContact C-N 3.29Å; F95-I97 PolarHBondContact O-N 3.24Å; I97-G102 CarbonylContact O-C 3.6Å; I97-G102 VanDerWaalsContact O-C 3.32Å; I97-G102 WeakPolarHBondContact O-CA 3.39Å; I97-G102 PolarHBondContact O-N 3.44Å; I97-I103 HydrophobicContact CG2-CB 4.26Å; I97-I103 HydrophobicContact CG2-CG1 4.25Å; I97-F110 HydrophobicContact CD1-CD2 4.45Å; I97-F110 HydrophobicContact CD1-CE2 3.86Å; I97-F110 HydrophobicContact CG1-CE2 3.65Å; I97-V149 HydrophobicContact CD1-CB 4.37Å; I97-V149 HydrophobicContact CD1-CG1 3.99Å; I97-A150 HydrophobicContact CD1-CB 3.62Å
98	D	74	Confident	83.8	Confident	28 Å²	28	41.9 Å²	41.9	15%	0.15	22%	0.217	C	C	.	.	I	π-helix	trans	-78.6	-32.6	-167.4	-63.5	-18.4	0	0	0	112.9	G94 F95 T244	G94-D98 WeakPolarHBondContact O-CB 3.36Å; G94-D98 PolarHBondContact O-N 3.07Å; F95-D98 PolarHBondContact O-N 3.21Å; D98-T244 PolarHBondContact OD1-OG1 3.2Å; D98-T244 PolarHBondContact OD2-OG1 3.2Å
99	R	75.1	Confident	84.1	Confident	112 Å²	112	39.6 Å²	39.6	42%	0.423	20%	0.201	S	C	.	.	I	π-helix	trans	-112.3	-34.7	-172.2	-62.4	-64.1	-174.2	146.1	-2.7	114.5	F95 G245	F95-R99 HydrophobicContact CD2-CB 4.21Å; F95-R99 HydrophobicContact CD2-CG 3.9Å; F95-R99 HydrophobicContact CE2-CB 3.92Å; F95-R99 HydrophobicContact CE2-CG 3.79Å; F95-R99 HydrophobicContact CZ-CB 4.18Å; F95-R99 WeakPolarHBondContact O-CB 3.26Å; F95-R99 PolarHBondContact O-N 3.29Å; R99-G245 PolarHBondContact NH2-O 3.31Å; R99-G245 VanDerWaalsContact NH2-O 3.12Å
100	V	82.7	Confident	84.5	Confident	82 Å²	82	38.3 Å²	38.3	50%	0.497	20%	0.195	S	C	.	.	I	π-helix	trans	-99.5	-60.4	-168.8	-173.9	0	0	0	0	112	F95 L96	F95-V100 HydrophobicContact CD1-CG2 4.37Å; F95-V100 HydrophobicContact CE1-CG2 3.86Å; F95-V100 HydrophobicContact CZ-CG2 4.49Å; L96-V100 HydrophobicContact CD2-CB 4.34Å; L96-V100 HydrophobicContact CD2-CG2 4.03Å; L96-V100 WeakPolarHBondContact O-CB 3.44Å; L96-V100 PolarHBondContact O-N 2.89Å
101	F	84.8	Confident	85.1	Confident	75 Å²	75	37.8 Å²	37.8	33%	0.329	19%	0.191	S	C	.	.	I	π-helix	trans	-98.4	-26.9	-170.6	-56	-55.7	0	0	0	113.3	L96 L105 I109	L96-F101 HydrophobicContact CB-CD2 3.99Å; L96-F101 HydrophobicContact CB-CE2 3.96Å; L96-F101 HydrophobicContact CD1-CE2 4.4Å; L96-F101 HydrophobicContact CD2-CE2 3.91Å; L96-F101 HydrophobicContact CD2-CZ 4.48Å; L96-F101 HydrophobicContact CG-CE2 4.3Å; L96-F101 WeakPolarHBondContact O-CD2 3.48Å; L96-F101 PolarHBondContact O-N 2.84Å; F101-L105 HydrophobicContact CB-CB 4.36Å; F101-L105 HydrophobicContact CB-CD2 4.49Å; F101-L105 HydrophobicContact CB-CG 4.46Å; F101-L105 HydrophobicContact CD1-CD2 4.46Å; F101-L105 WeakPolarHBondContact O-CB 3.38Å; F101-I109 HydrophobicContact CD1-CD1 3.91Å; F101-I109 HydrophobicContact CD2-CD1 4.49Å; F101-I109 HydrophobicContact CE1-CD1 4.13Å; F101-I109 HydrophobicContact CG-CD1 4.12Å
102	G	84.9	Confident	85.9	Confident	17 Å²	17	40.5 Å²	40.5	18%	0.175	21%	0.206	C	C	.	.	H	α-helix	trans	75.9	160.4	-163.9	0	0	0	0	0	111.6	I97 R104 G106	I97-G102 CarbonylContact O-C 3.6Å; I97-G102 VanDerWaalsContact O-C 3.32Å; I97-G102 WeakPolarHBondContact O-CA 3.39Å; I97-G102 PolarHBondContact O-N 3.44Å; G102-R104 VanDerWaalsContact C-N 3.31Å; G102-R104 PolarHBondContact O-N 3.01Å; G102-G106 PolarHBondContact O-N 3.42Å
103	I	86.1	Confident	86.7	Confident	16 Å²	16	40.7 Å²	40.7	8%	0.082	20%	0.204	C	C	.	.	H	α-helix	trans	-57.4	-39.9	-174.1	-156.2	175	0	0	0	113.8	I97 T107 T153 Y154	I97-I103 HydrophobicContact CG2-CB 4.26Å; I97-I103 HydrophobicContact CG2-CG1 4.25Å; I103-T107 VanDerWaalsContact O-CB 3.29Å; I103-T107 WeakPolarHBondContact O-CB 3.39Å; I103-T107 PolarHBondContact O-N 3.37Å; I103-T107 PolarHBondContact O-OG1 3.25Å; I103-T153 HydrophobicContact CD1-CG2 3.52Å; I103-T153 HydrophobicContact CG1-CG2 4.17Å; I103-Y154 HydrophobicContact CD1-CD1 3.82Å; I103-Y154 HydrophobicContact CD1-CD2 3.95Å; I103-Y154 HydrophobicContact CD1-CE1 4.16Å; I103-Y154 HydrophobicContact CD1-CE2 4.31Å; I103-Y154 HydrophobicContact CD1-CG 3.69Å; I103-Y154 HydrophobicContact CG1-CD1 4.42Å; I103-Y154 HydrophobicContact CG1-CD2 3.9Å; I103-Y154 HydrophobicContact CG1-CE1 4.39Å; I103-Y154 HydrophobicContact CG1-CE2 3.9Å; I103-Y154 HydrophobicContact CG1-CG 4.17Å; I103-Y154 HydrophobicContact CG2-CE1 4.13Å
104	R	91	Very high	87.8	Confident	37 Å²	37	40.8 Å²	40.8	14%	0.14	21%	0.205	C	C	.	.	H	α-helix	trans	-69.2	-56.8	-175.6	-59.2	175.7	-170.2	146.4	6	112	G102 T107 I108 Y154 D230 E234	G102-R104 VanDerWaalsContact C-N 3.31Å; G102-R104 PolarHBondContact O-N 3.01Å; R104-T107 PolarHBondContact O-N 2.95Å; R104-I108 WeakPolarHBondContact O-CG1 3.44Å; R104-I108 PolarHBondContact O-N 3.07Å; R104-Y154 WeakPolarHBondContact CA-OH 3.2Å; R104-Y154 WeakPolarHBondContact CG-OH 3.26Å; R104-D230 HydrophobicContact CG-CB 4.47Å; R104-D230 IonicContact CZ-OD2 3.68Å; R104-D230 IonicContact NE-OD2 3.96Å; R104-D230 PolarHBondContact NE-OD2 3.36Å; R104-D230 PolarHBondContact NH2-O 3.46Å; R104-D230 VanDerWaalsContact NH2-O 3.15Å; R104-D230 IonicContact NH2-OD2 3.06Å; R104-D230 PolarHBondContact NH2-OD2 2.96Å; R104-E234 IonicContact CZ-OE2 2.69Å; R104-E234 IonicContact NH1-OE2 3.56Å; R104-E234 PolarHBondContact NH1-OE2 3.3Å; R104-E234 IonicContact NH2-OE2 2.85Å; R104-E234 PolarHBondContact NH2-OE2 3.07Å
105	L	91.3	Very high	89	Confident	91 Å²	91	40.6 Å²	40.6	48%	0.476	20%	0.201	S	C	.	.	H	α-helix	trans	-69.3	-39.5	-177.3	-177.1	63.6	0	0	0	110.4	F101 T107 I108 I109	F101-L105 HydrophobicContact CB-CB 4.36Å; F101-L105 HydrophobicContact CB-CD2 4.49Å; F101-L105 HydrophobicContact CB-CG 4.46Å; F101-L105 HydrophobicContact CD1-CD2 4.46Å; F101-L105 WeakPolarHBondContact O-CB 3.38Å; L105-T107 PolarHBondContact O-N 3.46Å; L105-I108 PolarHBondContact O-N 3.36Å; L105-I109 HydrophobicContact CD1-CD1 4.14Å; L105-I109 HydrophobicContact CD1-CG1 4.27Å; L105-I109 HydrophobicContact CD2-CD1 4.3Å; L105-I109 HydrophobicContact CG-CD1 3.73Å; L105-I109 HydrophobicContact CG-CG1 4.29Å; L105-I109 WeakPolarHBondContact O-CB 3.4Å; L105-I109 VanDerWaalsContact O-CG1 3.28Å; L105-I109 WeakPolarHBondContact O-CG1 3.38Å; L105-I109 PolarHBondContact O-N 3.16Å
106	G	91.6	Very high	90	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-56.2	-48.5	174.7	0	0	0	0	0	112.2	G102 I108 I109 F110	G102-G106 PolarHBondContact O-N 3.42Å; G106-I108 PolarHBondContact O-N 2.85Å; G106-I109 PolarHBondContact O-N 3.39Å; G106-F110 WeakPolarHBondContact O-CD2 3.3Å; G106-F110 WeakPolarHBondContact O-CG 3.45Å; G106-F110 PolarHBondContact O-N 2.86Å
107	T	93.2	Very high	90.8	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-60.3	-43.2	177.8	-58.2	0	0	0	0	112.6	L46 I103 R104 L105 S111 L147 A150 Y154 A223	L46-T107 HydrophobicContact CD1-CG2 3.81Å; L46-T107 HydrophobicContact CD2-CG2 3.66Å; L46-T107 HydrophobicContact CG-CG2 4.31Å; I103-T107 VanDerWaalsContact O-CB 3.29Å; I103-T107 WeakPolarHBondContact O-CB 3.39Å; I103-T107 PolarHBondContact O-N 3.37Å; I103-T107 PolarHBondContact O-OG1 3.25Å; R104-T107 PolarHBondContact O-N 2.95Å; L105-T107 PolarHBondContact O-N 3.46Å; T107-S111 VanDerWaalsContact O-CB 3.24Å; T107-S111 WeakPolarHBondContact O-CB 3.2Å; T107-S111 PolarHBondContact O-N 3.35Å; T107-L147 HydrophobicContact CG2-CD1 3.93Å; T107-A150 HydrophobicContact CG2-CB 4.49Å; T107-A150 VanDerWaalsContact OG1-CB 3.3Å; T107-A150 WeakPolarHBondContact OG1-CB 3.31Å; T107-Y154 HydrophobicContact CG2-CE2 4.05Å; T107-Y154 WeakPolarHBondContact OG1-CE2 3.29Å; T107-A223 HydrophobicContact CG2-CB 4.09Å
108	I	96.1	Very high	91.7	Very high	45 Å²	45	37.9 Å²	37.9	23%	0.231	19%	0.192	C	C	.	.	H	α-helix	trans	-65	-43.9	178	-66.1	163.1	0	0	0	110.6	R104 L105 G106 S111 L112 L220 A223 L224	R104-I108 WeakPolarHBondContact O-CG1 3.44Å; R104-I108 PolarHBondContact O-N 3.07Å; L105-I108 PolarHBondContact O-N 3.36Å; G106-I108 PolarHBondContact O-N 2.85Å; I108-S111 PolarHBondContact O-N 3.41Å; I108-L112 WeakPolarHBondContact O-CB 3.01Å; I108-L112 PolarHBondContact O-N 2.9Å; I108-L220 HydrophobicContact CG2-CD1 4.46Å; I108-A223 HydrophobicContact CG1-CB 4.41Å; I108-L224 HydrophobicContact CD1-CD2 3.92Å; I108-L224 HydrophobicContact CG1-CD2 4.11Å; I108-L224 HydrophobicContact CG2-CD2 4.09Å
109	I	95.7	Very high	92.8	Very high	41 Å²	41	39.2 Å²	39.2	21%	0.21	20%	0.201	C	C	.	.	H	α-helix	trans	-62.1	-48.7	178.5	-71.7	170.9	0	0	0	110.7	F101 L105 G106 S111 L112 F113	F101-I109 HydrophobicContact CD1-CD1 3.91Å; F101-I109 HydrophobicContact CD2-CD1 4.49Å; F101-I109 HydrophobicContact CE1-CD1 4.13Å; F101-I109 HydrophobicContact CG-CD1 4.12Å; L105-I109 HydrophobicContact CD1-CD1 4.14Å; L105-I109 HydrophobicContact CD1-CG1 4.27Å; L105-I109 HydrophobicContact CD2-CD1 4.3Å; L105-I109 HydrophobicContact CG-CD1 3.73Å; L105-I109 HydrophobicContact CG-CG1 4.29Å; L105-I109 WeakPolarHBondContact O-CB 3.4Å; L105-I109 VanDerWaalsContact O-CG1 3.28Å; L105-I109 WeakPolarHBondContact O-CG1 3.38Å; L105-I109 PolarHBondContact O-N 3.16Å; G106-I109 PolarHBondContact O-N 3.39Å; I109-S111 PolarHBondContact O-N 3.1Å; I109-L112 WeakPolarHBondContact O-CB 3.14Å; I109-L112 PolarHBondContact O-N 3.07Å; I109-F113 HydrophobicContact CG2-CD2 3.78Å; I109-F113 HydrophobicContact CG2-CE2 3.54Å; I109-F113 VanDerWaalsContact O-CD2 3.26Å; I109-F113 WeakPolarHBondContact O-CD2 3.22Å; I109-F113 PolarHBondContact O-N 2.92Å
110	F	95	Very high	94	Very high	6 Å²	6	36.1 Å²	36.1	3%	0.026	19%	0.193	C	C	.	.	H	α-helix	trans	-66.4	-39.1	179.7	-62.5	-45	0	0	0	112.3	L96 I97 G106 L112 F113 V114 G143 S146 L147	L96-F110 HydrophobicContact CB-CZ 4.3Å; L96-F110 HydrophobicContact CD1-CZ 4.3Å; I97-F110 HydrophobicContact CD1-CD2 4.45Å; I97-F110 HydrophobicContact CD1-CE2 3.86Å; I97-F110 HydrophobicContact CG1-CE2 3.65Å; G106-F110 WeakPolarHBondContact O-CD2 3.3Å; G106-F110 WeakPolarHBondContact O-CG 3.45Å; G106-F110 PolarHBondContact O-N 2.86Å; F110-L112 VanDerWaalsContact C-N 3.28Å; F110-L112 PolarHBondContact O-N 2.79Å; F110-F113 HydrophobicContact CD1-CD2 4.48Å; F110-F113 PolarHBondContact O-N 3.37Å; F110-V114 WeakPolarHBondContact O-CG2 3.46Å; F110-V114 PolarHBondContact O-N 3.44Å; F110-G143 WeakPolarHBondContact O-CA 2.99Å; F110-S146 VanDerWaalsContact CD1-CB 3.45Å; F110-S146 VanDerWaalsContact CG-CB 3.5Å; F110-L147 HydrophobicContact CB-CB 4.12Å; F110-L147 HydrophobicContact CB-CD1 4.48Å
111	S	96.6	Very high	94.7	Very high	2 Å²	2	32.3 Å²	32.3	1%	0.014	17%	0.169	C	C	.	.	H	α-helix	trans	-62.8	-36.1	173	-171.6	0	0	0	0	112.1	T107 I108 I109 V114 C115 L220	T107-S111 VanDerWaalsContact O-CB 3.24Å; T107-S111 WeakPolarHBondContact O-CB 3.2Å; T107-S111 PolarHBondContact O-N 3.35Å; I108-S111 PolarHBondContact O-N 3.41Å; I109-S111 PolarHBondContact O-N 3.1Å; S111-V114 PolarHBondContact O-N 2.66Å; S111-C115 WeakPolarHBondContact O-CB 3.38Å; S111-C115 PolarHBondContact O-N 3.19Å; S111-L220 VanDerWaalsContact OG-CA 3.25Å; S111-L220 WeakPolarHBondContact OG-CA 3.11Å; S111-L220 PolarHBondContact OG-N 3.18Å
112	L	97.6	Very high	95.4	Very high	88 Å²	88	28.7 Å²	28.7	46%	0.461	15%	0.153	S	C	.	.	H	α-helix	trans	-65.3	-43	173.5	-175.1	66.9	0	0	0	111.7	I108 I109 F110 V114 C115 V116 L220	I108-L112 WeakPolarHBondContact O-CB 3.01Å; I108-L112 PolarHBondContact O-N 2.9Å; I109-L112 WeakPolarHBondContact O-CB 3.14Å; I109-L112 PolarHBondContact O-N 3.07Å; F110-L112 VanDerWaalsContact C-N 3.28Å; F110-L112 PolarHBondContact O-N 2.79Å; L112-V114 VanDerWaalsContact C-N 3.35Å; L112-V114 PolarHBondContact O-N 3.4Å; L112-C115 PolarHBondContact O-N 3.13Å; L112-V116 HydrophobicContact CD1-CG2 4.01Å; L112-V116 HydrophobicContact CG-CG2 4.13Å; L112-V116 WeakPolarHBondContact O-CB 3.44Å; L112-V116 VanDerWaalsContact O-CG2 3.28Å; L112-V116 WeakPolarHBondContact O-CG2 3.47Å; L112-V116 PolarHBondContact O-N 3.22Å; L112-L220 HydrophobicContact CD1-CD2 4.27Å
113	F	97.8	Very high	96	Very high	78 Å²	78	29.4 Å²	29.4	34%	0.342	16%	0.158	S	C	.	.	H	α-helix	trans	-58.7	-44.2	174	-83	-66.8	0	0	0	112.3	I109 F110 G117 V139 I142	I109-F113 HydrophobicContact CG2-CD2 3.78Å; I109-F113 HydrophobicContact CG2-CE2 3.54Å; I109-F113 VanDerWaalsContact O-CD2 3.26Å; I109-F113 WeakPolarHBondContact O-CD2 3.22Å; I109-F113 PolarHBondContact O-N 2.92Å; F110-F113 HydrophobicContact CD1-CD2 4.48Å; F110-F113 PolarHBondContact O-N 3.37Å; F113-G117 PolarHBondContact O-N 3.43Å; F113-V139 HydrophobicContact CD1-CG1 4.04Å; F113-I142 HydrophobicContact CD1-CG2 4.14Å; F113-I142 HydrophobicContact CD2-CG2 4.13Å; F113-I142 HydrophobicContact CE1-CG2 4.32Å; F113-I142 HydrophobicContact CE2-CG2 4.31Å; F113-I142 HydrophobicContact CG-CG2 4.05Å; F113-I142 HydrophobicContact CZ-CG2 4.4Å
114	V	97.9	Very high	96.6	Very high	3 Å²	3	28.7 Å²	28.7	2%	0.018	15%	0.154	C	C	.	.	H	α-helix	trans	-58.8	-49.3	174.2	172.9	0	0	0	0	110.8	F110 S111 L112 G117 Q118 F140 G143 L147	F110-V114 WeakPolarHBondContact O-CG2 3.46Å; F110-V114 PolarHBondContact O-N 3.44Å; S111-V114 PolarHBondContact O-N 2.66Å; L112-V114 VanDerWaalsContact C-N 3.35Å; L112-V114 PolarHBondContact O-N 3.4Å; V114-G117 PolarHBondContact O-N 3.16Å; V114-Q118 PolarHBondContact O-N 2.85Å; V114-F140 HydrophobicContact CB-CE2 4.49Å; V114-F140 HydrophobicContact CG1-CD2 4.01Å; V114-F140 HydrophobicContact CG1-CE1 4.44Å; V114-F140 HydrophobicContact CG1-CE2 3.48Å; V114-F140 VanDerWaalsContact CG1-CE2 3.48Å; V114-F140 HydrophobicContact CG1-CZ 3.74Å; V114-F140 WeakPolarHBondContact O-CD2 3.34Å; V114-G143 VanDerWaalsContact CG2-C 3.48Å; V114-L147 HydrophobicContact CG2-CD2 4.22Å
115	C	98.3	Very high	96.9	Very high	12 Å²	12	26.9 Å²	26.9	8%	0.081	15%	0.147	C	C	.	.	H	α-helix	trans	-64.3	-47.2	-179	-171	0	0	0	0	112.4	S111 L112 Q118 V119 C216	S111-C115 WeakPolarHBondContact O-CB 3.38Å; S111-C115 PolarHBondContact O-N 3.19Å; L112-C115 PolarHBondContact O-N 3.13Å; C115-Q118 PolarHBondContact O-N 2.63Å; C115-V119 WeakPolarHBondContact O-CG2 3.45Å; C115-V119 PolarHBondContact O-N 3.2Å; C115-C216 HydrophobicContact CB-CB 4.03Å
116	V	98.5	Very high	97.1	Very high	61 Å²	61	28.4 Å²	28.4	37%	0.37	15%	0.147	S	C	.	.	H	α-helix	trans	-64.5	-43.9	178.9	170.8	0	0	0	0	110.5	L112 Q118 V119 I120 V139	L112-V116 HydrophobicContact CD1-CG2 4.01Å; L112-V116 HydrophobicContact CG-CG2 4.13Å; L112-V116 WeakPolarHBondContact O-CB 3.44Å; L112-V116 VanDerWaalsContact O-CG2 3.28Å; L112-V116 WeakPolarHBondContact O-CG2 3.47Å; L112-V116 PolarHBondContact O-N 3.22Å; V116-Q118 VanDerWaalsContact C-N 3.32Å; V116-Q118 PolarHBondContact O-N 2.9Å; V116-V119 PolarHBondContact O-N 3.21Å; V116-I120 HydrophobicContact CG1-CD1 3.68Å; V116-I120 HydrophobicContact CG1-CG1 4.26Å; V116-I120 VanDerWaalsContact O-CG1 3.27Å; V116-I120 WeakPolarHBondContact O-CG1 3.39Å; V116-I120 PolarHBondContact O-N 3.04Å; V116-V139 HydrophobicContact CG1-CG1 4.35Å
117	G	98.5	Very high	97.4	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-58.3	-42.3	176	0	0	0	0	0	112.7	F113 V114 I120 F121 G136	F113-G117 PolarHBondContact O-N 3.43Å; V114-G117 PolarHBondContact O-N 3.16Å; G117-I120 PolarHBondContact O-N 3.35Å; G117-F121 WeakPolarHBondContact O-CB 3.44Å; G117-F121 PolarHBondContact O-N 3.29Å; G117-G136 CarbonylContact C-O 3.32Å; G117-G136 WeakPolarHBondContact CA-O 3.35Å; G117-G136 CarbonylContact O-C 3.44Å; G117-G136 WeakPolarHBondContact O-CA 3.41Å
118	Q	98.6	Very high	97.6	Very high	1 Å²	1	35 Å²	35	1%	0.005	19%	0.186	C	C	.	.	H	α-helix	trans	-66.2	-39.4	175.7	176.4	58.8	23.1	0	0	112.4	C53 N56 V114 C115 V116 F121 A122 F140 L209 A213	C53-Q118 HydrophobicContact CB-CG 4.23Å; N56-Q118 PolarHBondContact ND2-NE2 2.8Å; N56-Q118 PolarHBondContact ND2-OE1 3.5Å; V114-Q118 PolarHBondContact O-N 2.85Å; C115-Q118 PolarHBondContact O-N 2.63Å; V116-Q118 VanDerWaalsContact C-N 3.32Å; V116-Q118 PolarHBondContact O-N 2.9Å; Q118-F121 PolarHBondContact O-N 2.98Å; Q118-A122 WeakPolarHBondContact O-CB 3.07Å; Q118-A122 PolarHBondContact O-N 2.86Å; Q118-F140 HydrophobicContact CB-CD2 3.96Å; Q118-F140 HydrophobicContact CB-CE2 4.06Å; Q118-L209 PolarHBondContact NE2-O 3.03Å; Q118-A213 HydrophobicContact CG-CB 3.74Å
119	V	98.6	Very high	97.6	Very high	57 Å²	57	37.2 Å²	37.2	35%	0.345	20%	0.196	S	C	.	.	H	α-helix	trans	-64.7	-43.1	175.7	169.5	0	0	0	0	110.9	C115 V116 F121 A122 A123 M210 A213	C115-V119 WeakPolarHBondContact O-CG2 3.45Å; C115-V119 PolarHBondContact O-N 3.2Å; V116-V119 PolarHBondContact O-N 3.21Å; V119-F121 VanDerWaalsContact C-N 3.35Å; V119-A122 PolarHBondContact O-N 2.91Å; V119-A123 VanDerWaalsContact O-CB 3.28Å; V119-A123 WeakPolarHBondContact O-CB 3.17Å; V119-A123 PolarHBondContact O-N 3.1Å; V119-M210 HydrophobicContact CG1-CE 4.25Å; V119-M210 HydrophobicContact CG1-SD 4.48Å; V119-M210 HydrophobicContact CG2-SD 4.32Å; V119-A213 HydrophobicContact CG2-CB 4.19Å
120	I	98.7	Very high	97.7	Very high	47 Å²	47	36.9 Å²	36.9	24%	0.241	19%	0.193	C	C	.	.	H	α-helix	trans	-62.3	-44.1	175.3	-66.1	167.2	0	0	0	110.2	V116 G117 A122 A123 G124 L132 V139	V116-I120 HydrophobicContact CG1-CD1 3.68Å; V116-I120 HydrophobicContact CG1-CG1 4.26Å; V116-I120 VanDerWaalsContact O-CG1 3.27Å; V116-I120 WeakPolarHBondContact O-CG1 3.39Å; V116-I120 PolarHBondContact O-N 3.04Å; G117-I120 PolarHBondContact O-N 3.35Å; I120-A122 PolarHBondContact O-N 3.47Å; I120-A123 PolarHBondContact O-N 3.39Å; I120-G124 PolarHBondContact O-N 2.9Å; I120-L132 HydrophobicContact CG2-CD1 3.63Å; I120-L132 HydrophobicContact CG2-CG 4.07Å; I120-L132 WeakPolarHBondContact CG2-O 3.28Å; I120-V139 HydrophobicContact CD1-CB 4.5Å; I120-V139 HydrophobicContact CD1-CG1 4.41Å; I120-V139 HydrophobicContact CD1-CG2 4.29Å
121	F	98.6	Very high	97.9	Very high	1 Å²	1	44 Å²	44	0%	0.004	22%	0.22	C	C	.	.	H	α-helix	trans	-58.7	-47.8	176.8	179	-117.8	0	0	0	111.9	N56 P57 L78 G117 Q118 V119 G124 A125 M133 R137 L209	N56-F121 HydrophobicContact CB-CE1 4.28Å; P57-F121 HydrophobicContact CG-CE1 4.43Å; P57-F121 HydrophobicContact CG-CZ 3.94Å; L78-F121 HydrophobicContact CD1-CE2 3.98Å; L78-F121 HydrophobicContact CD1-CZ 4.2Å; L78-F121 HydrophobicContact CD2-CE2 3.84Å; L78-F121 HydrophobicContact CG-CE2 4.47Å; G117-F121 WeakPolarHBondContact O-CB 3.44Å; G117-F121 PolarHBondContact O-N 3.29Å; Q118-F121 PolarHBondContact O-N 2.98Å; V119-F121 VanDerWaalsContact C-N 3.35Å; F121-G124 PolarHBondContact O-N 3.12Å; F121-A125 PolarHBondContact O-N 3.49Å; F121-M133 HydrophobicContact CD2-CB 3.65Å; F121-M133 HydrophobicContact CD2-CE 4.09Å; F121-M133 HydrophobicContact CD2-CG 4.18Å; F121-M133 WeakPolarHBondContact CD2-O 3.48Å; F121-M133 HydrophobicContact CE2-CB 3.78Å; F121-M133 HydrophobicContact CE2-CE 3.32Å; F121-M133 HydrophobicContact CE2-CG 4.28Å; F121-M133 HydrophobicContact CZ-CE 3.64Å; F121-R137 HydrophobicContact CD2-CG 3.9Å; F121-R137 HydrophobicContact CE2-CG 4.07Å; F121-L209 HydrophobicContact CD1-CD1 4.01Å; F121-L209 HydrophobicContact CD1-CD2 4.3Å; F121-L209 HydrophobicContact CE1-CD1 3.61Å; F121-L209 HydrophobicContact CE1-CD2 3.73Å; F121-L209 HydrophobicContact CE1-CG 4.26Å; F121-L209 HydrophobicContact CZ-CD1 4.12Å
122	A	98.4	Very high	97.9	Very high	0 Å²	0	45.9 Å²	45.9	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-64.4	-39.8	176.2	0	0	0	0	0	112.6	Q118 V119 I120 G124 A125 W126 G206 L209 M210	Q118-A122 WeakPolarHBondContact O-CB 3.07Å; Q118-A122 PolarHBondContact O-N 2.86Å; V119-A122 PolarHBondContact O-N 2.91Å; I120-A122 PolarHBondContact O-N 3.47Å; A122-G124 VanDerWaalsContact C-N 3.34Å; A122-A125 PolarHBondContact O-N 3.33Å; A122-W126 PolarHBondContact O-N 3.02Å; A122-G206 WeakPolarHBondContact O-CA 3.14Å; A122-L209 HydrophobicContact CB-CB 3.63Å; A122-M210 HydrophobicContact CB-CB 4.22Å; A122-M210 HydrophobicContact CB-CE 3.77Å; A122-M210 HydrophobicContact CB-SD 4.36Å
123	A	98.4	Very high	98	Very high	32 Å²	32	41.7 Å²	41.7	26%	0.264	21%	0.207	S	C	.	.	H	α-helix	trans	-67	-34.2	176.8	0	0	0	0	0	112.6	V119 I120 W126 S127	V119-A123 VanDerWaalsContact O-CB 3.28Å; V119-A123 WeakPolarHBondContact O-CB 3.17Å; V119-A123 PolarHBondContact O-N 3.1Å; I120-A123 PolarHBondContact O-N 3.39Å; A123-W126 PolarHBondContact O-N 3.29Å; A123-S127 VanDerWaalsContact O-CB 3.27Å; A123-S127 WeakPolarHBondContact O-CB 3.31Å; A123-S127 PolarHBondContact O-N 3Å; A123-S127 PolarHBondContact O-OG 3.5Å
124	G	97.9	Very high	98	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-61	-47	172.3	0	0	0	0	0	112.2	I120 F121 A122 S127 N128 H129	I120-G124 PolarHBondContact O-N 2.9Å; F121-G124 PolarHBondContact O-N 3.12Å; A122-G124 VanDerWaalsContact C-N 3.34Å; G124-S127 PolarHBondContact O-N 3Å; G124-N128 PolarHBondContact O-N 3.43Å; G124-N128 VanDerWaalsContact O-N 3.09Å; G124-H129 PolarHBondContact O-N 3.33Å
125	A	97.6	Very high	98	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-63	-48	173.7	0	0	0	0	0	111.6	M68 F121 A122 S127 N128 M133 H202 L205 L209	M68-A125 HydrophobicContact SD-CB 4.39Å; F121-A125 PolarHBondContact O-N 3.49Å; A122-A125 PolarHBondContact O-N 3.33Å; A125-S127 VanDerWaalsContact C-N 3.28Å; A125-S127 PolarHBondContact O-N 3.05Å; A125-N128 PolarHBondContact O-N 3.26Å; A125-M133 HydrophobicContact CB-CE 4.1Å; A125-M133 HydrophobicContact CB-CG 4.47Å; A125-M133 HydrophobicContact CB-SD 3.93Å; A125-H202 CarbonylContact C-O 3.48Å; A125-H202 CarbonylContact O-C 3.55Å; A125-H202 WeakPolarHBondContact O-CB 3.48Å; A125-L205 HydrophobicContact CB-CB 4.47Å; A125-L205 HydrophobicContact CB-CD2 3.97Å; A125-L205 HydrophobicContact CB-CG 3.93Å; A125-L209 HydrophobicContact CB-CD1 3.84Å
126	W	96.8	Very high	98	Very high	123 Å²	123	40.8 Å²	40.8	47%	0.466	21%	0.209	S	C	.	.	H	α-helix	trans	-54.2	-47.2	177.7	-171.7	-54.4	0	0	0	111.6	A122 A123 N128 H202 I207	A122-W126 PolarHBondContact O-N 3.02Å; A123-W126 PolarHBondContact O-N 3.29Å; W126-N128 PolarHBondContact O-N 2.95Å; W126-H202 PolarHBondContact O-ND1 3.11Å; W126-I207 HydrophobicContact CE3-CG1 3.72Å; W126-I207 HydrophobicContact CH2-CD1 4.14Å; W126-I207 HydrophobicContact CH2-CG1 3.7Å; W126-I207 HydrophobicContact CZ2-CG1 4.49Å; W126-I207 HydrophobicContact CZ3-CB 4.39Å; W126-I207 HydrophobicContact CZ3-CD1 4.2Å; W126-I207 HydrophobicContact CZ3-CG1 3.27Å
127	S	97.1	Very high	98	Very high	60 Å²	60	37.9 Å²	37.9	42%	0.42	19%	0.191	S	C	.	.	T	Hydrogen-bonded Turn	trans	-81.1	0.3	-176	-48.8	0	0	0	0	113.3	A123 G124 A125 H129	A123-S127 VanDerWaalsContact O-CB 3.27Å; A123-S127 WeakPolarHBondContact O-CB 3.31Å; A123-S127 PolarHBondContact O-N 3Å; A123-S127 PolarHBondContact O-OG 3.5Å; G124-S127 PolarHBondContact O-N 3Å; A125-S127 VanDerWaalsContact C-N 3.28Å; A125-S127 PolarHBondContact O-N 3.05Å; S127-H129 VanDerWaalsContact C-N 3.31Å; S127-H129 PolarHBondContact O-CE1 3.07Å; S127-H129 PolarHBondContact O-N 3.24Å; S127-H129 PolarHBondContact O-ND1 2.92Å
128	N	96.8	Very high	98	Very high	78 Å²	78	41.4 Å²	41.4	42%	0.417	21%	0.207	S	C	.	.	T	Hydrogen-bonded Turn	trans	55.7	38.5	-174.3	-159.8	26	0	0	0	114.4	G124 A125 W126 H202	G124-N128 PolarHBondContact O-N 3.43Å; G124-N128 VanDerWaalsContact O-N 3.09Å; A125-N128 PolarHBondContact O-N 3.26Å; W126-N128 PolarHBondContact O-N 2.95Å; N128-H202 HydrophobicContact CB-CB 4.09Å
129	H	97.7	Very high	98	Very high	92 Å²	92	42.8 Å²	42.8	43%	0.426	22%	0.215	S	C	.	.			trans	-119.2	100.6	178.3	-72.7	86.9	0	0	0	110.3	G124 S127 W131 L132 M133	G124-H129 PolarHBondContact O-N 3.33Å; S127-H129 VanDerWaalsContact C-N 3.31Å; S127-H129 PolarHBondContact O-CE1 3.07Å; S127-H129 PolarHBondContact O-N 3.24Å; S127-H129 PolarHBondContact O-ND1 2.92Å; H129-W131 AromaticContact CD2-NE1 3.46Å; H129-W131 PolarHBondContact CD2-NE1 2.98Å; H129-W131 AromaticContact CG-NE1 3.91Å; H129-W131 PolarHBondContact O-N 3.29Å; H129-L132 HydrophobicContact CB-CB 4.12Å; H129-L132 WeakPolarHBondContact O-CB 3.32Å; H129-L132 PolarHBondContact O-N 2.94Å; H129-L132 VanDerWaalsContact O-N 3.11Å; H129-M133 PolarHBondContact O-N 3.31Å
130	F	97.6	Very high	98	Very high	34 Å²	34	40.1 Å²	40.1	15%	0.149	20%	0.199	C	C	.	.	H	α-helix	trans	-61.9	-39.7	-176.9	-176.6	-110.9	0	0	0	113.4	M68 L70 E74 Q77 L78 L132 M133 E134	M68-F130 HydrophobicContact CE-CB 4.29Å; L70-F130 HydrophobicContact CD1-CD2 3.47Å; L70-F130 VanDerWaalsContact CD1-CD2 3.47Å; L70-F130 HydrophobicContact CD1-CE2 3.41Å; L70-F130 VanDerWaalsContact CD1-CE2 3.41Å; L70-F130 HydrophobicContact CD1-CG 4.28Å; L70-F130 HydrophobicContact CD1-CZ 4.2Å; L70-F130 HydrophobicContact CD2-CB 4.27Å; L70-F130 HydrophobicContact CD2-CD1 4.27Å; L70-F130 HydrophobicContact CD2-CD2 3.92Å; L70-F130 HydrophobicContact CD2-CE2 4.36Å; L70-F130 HydrophobicContact CD2-CG 3.87Å; L70-F130 HydrophobicContact CG-CD2 4.34Å; E74-F130 HydrophobicContact CB-CE1 4.4Å; E74-F130 WeakPolarHBondContact O-CZ 3.33Å; Q77-F130 HydrophobicContact CB-CZ 4.46Å; L78-F130 HydrophobicContact CD1-CE2 4.15Å; L78-F130 HydrophobicContact CD2-CE2 3.59Å; L78-F130 HydrophobicContact CD2-CZ 3.86Å; L78-F130 HydrophobicContact CG-CE2 3.82Å; L78-F130 HydrophobicContact CG-CZ 4Å; F130-L132 PolarHBondContact O-N 2.84Å; F130-L132 VanDerWaalsContact O-N 3.13Å; F130-M133 HydrophobicContact CD2-CB 4.4Å; F130-M133 HydrophobicContact CD2-SD 4.14Å; F130-M133 WeakPolarHBondContact O-CA 3.1Å; F130-M133 WeakPolarHBondContact O-CB 3.44Å; F130-M133 PolarHBondContact O-N 2.95Å; F130-E134 HydrophobicContact CD1-CG 4.12Å; F130-E134 VanDerWaalsContact CE1-CD 3.46Å; F130-E134 HydrophobicContact CE1-CG 3.66Å; F130-E134 WeakPolarHBondContact CE1-OE1 3.45Å; F130-E134 HydrophobicContact CZ-CG 3.9Å; F130-E134 PolarHBondContact O-N 3.26Å
131	W	97.4	Very high	97.9	Very high	156 Å²	156	37.9 Å²	37.9	59%	0.591	19%	0.188	S	C	*	.	H	α-helix	trans	-57.7	-31.1	176.2	72.3	-96.7	0	0	0	112.8	H129 E134 A135	H129-W131 AromaticContact CD2-NE1 3.46Å; H129-W131 PolarHBondContact CD2-NE1 2.98Å; H129-W131 AromaticContact CG-NE1 3.91Å; H129-W131 PolarHBondContact O-N 3.29Å; W131-E134 PolarHBondContact O-N 3.15Å; W131-A135 WeakPolarHBondContact O-CB 3.21Å; W131-A135 PolarHBondContact O-N 3.04Å
132	L	98.3	Very high	97.7	Very high	41 Å²	41	39.5 Å²	39.5	22%	0.215	20%	0.196	C	C	.	.	H	α-helix	trans	-74.7	-32	177	-173.6	60.1	0	0	0	110.7	I120 H129 F130 G136	I120-L132 HydrophobicContact CG2-CD1 3.63Å; I120-L132 HydrophobicContact CG2-CG 4.07Å; I120-L132 WeakPolarHBondContact CG2-O 3.28Å; H129-L132 HydrophobicContact CB-CB 4.12Å; H129-L132 WeakPolarHBondContact O-CB 3.32Å; H129-L132 PolarHBondContact O-N 2.94Å; H129-L132 VanDerWaalsContact O-N 3.11Å; F130-L132 PolarHBondContact O-N 2.84Å; F130-L132 VanDerWaalsContact O-N 3.13Å; L132-G136 PolarHBondContact O-N 3.41Å
133	M	98.5	Very high	97.5	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-62.9	-45.7	169.3	-61.8	178.3	66	0	0	111	V64 M68 L78 F121 A125 H129 F130 G136 R137	V64-M133 HydrophobicContact CG1-CE 4.33Å; M68-M133 HydrophobicContact CE-SD 3.56Å; M68-M133 VanDerWaalsContact CE-SD 3.56Å; M68-M133 HydrophobicContact CG-SD 4Å; M68-M133 HydrophobicContact SD-SD 3.87Å; L78-M133 HydrophobicContact CD1-CE 4.35Å; L78-M133 HydrophobicContact CD2-CB 3.99Å; F121-M133 HydrophobicContact CD2-CB 3.65Å; F121-M133 HydrophobicContact CD2-CE 4.09Å; F121-M133 HydrophobicContact CD2-CG 4.18Å; F121-M133 WeakPolarHBondContact CD2-O 3.48Å; F121-M133 HydrophobicContact CE2-CB 3.78Å; F121-M133 HydrophobicContact CE2-CE 3.32Å; F121-M133 HydrophobicContact CE2-CG 4.28Å; F121-M133 HydrophobicContact CZ-CE 3.64Å; A125-M133 HydrophobicContact CB-CE 4.1Å; A125-M133 HydrophobicContact CB-CG 4.47Å; A125-M133 HydrophobicContact CB-SD 3.93Å; H129-M133 PolarHBondContact O-N 3.31Å; F130-M133 HydrophobicContact CD2-CB 4.4Å; F130-M133 HydrophobicContact CD2-SD 4.14Å; F130-M133 WeakPolarHBondContact O-CA 3.1Å; F130-M133 WeakPolarHBondContact O-CB 3.44Å; F130-M133 PolarHBondContact O-N 2.95Å; M133-G136 WeakPolarHBondContact O-CA 3.49Å; M133-G136 PolarHBondContact O-N 3.17Å; M133-G136 VanDerWaalsContact O-N 3.16Å; M133-R137 WeakPolarHBondContact O-CG 3.45Å; M133-R137 PolarHBondContact O-N 2.87Å
134	E	98.4	Very high	97.2	Very high	36 Å²	36	38.1 Å²	38.1	17%	0.168	19%	0.185	C	C	.	.	H	α-helix	trans	-59.7	-46.7	175.6	-66	-178.9	123	0	0	112	Q77 L78 W81 F130 W131 G136 R137 F138	Q77-E134 WeakPolarHBondContact CB-OE1 3.29Å; L78-E134 HydrophobicContact CD2-CG 4.32Å; W81-E134 VanDerWaalsContact CD1-OE1 3.3Å; W81-E134 HydrophobicContact CD2-CB 4.49Å; W81-E134 HydrophobicContact CG-CB 3.99Å; W81-E134 HydrophobicContact CG-CG 4.44Å; W81-E134 VanDerWaalsContact NE1-CD 3.31Å; W81-E134 PolarHBondContact NE1-OE1 2.98Å; F130-E134 HydrophobicContact CD1-CG 4.12Å; F130-E134 VanDerWaalsContact CE1-CD 3.46Å; F130-E134 HydrophobicContact CE1-CG 3.66Å; F130-E134 WeakPolarHBondContact CE1-OE1 3.45Å; F130-E134 HydrophobicContact CZ-CG 3.9Å; F130-E134 PolarHBondContact O-N 3.26Å; W131-E134 PolarHBondContact O-N 3.15Å; E134-G136 VanDerWaalsContact C-N 3.27Å; E134-G136 PolarHBondContact O-N 3.08Å; E134-R137 PolarHBondContact O-N 3.33Å; E134-R137 VanDerWaalsContact O-N 3.09Å; E134-F138 PolarHBondContact O-N 3.42Å
135	A	98.5	Very high	96.8	Very high	37 Å²	37	39.8 Å²	39.8	31%	0.306	19%	0.193	S	C	.	.	H	α-helix	trans	-58.6	-40.2	174.4	0	0	0	0	0	111.9	W131 F138 V139	W131-A135 WeakPolarHBondContact O-CB 3.21Å; W131-A135 PolarHBondContact O-N 3.04Å; A135-F138 PolarHBondContact O-N 3.42Å; A135-V139 WeakPolarHBondContact O-CG2 3.42Å; A135-V139 PolarHBondContact O-N 2.92Å
136	G	98.4	Very high	96.5	Very high	0 Å²	0	39.9 Å²	39.9	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-60	-43.6	173.2	0	0	0	0	0	112.7	G117 L132 M133 E134 V139 F140	G117-G136 CarbonylContact C-O 3.32Å; G117-G136 WeakPolarHBondContact CA-O 3.35Å; G117-G136 CarbonylContact O-C 3.44Å; G117-G136 WeakPolarHBondContact O-CA 3.41Å; L132-G136 PolarHBondContact O-N 3.41Å; M133-G136 WeakPolarHBondContact O-CA 3.49Å; M133-G136 PolarHBondContact O-N 3.17Å; M133-G136 VanDerWaalsContact O-N 3.16Å; E134-G136 VanDerWaalsContact C-N 3.27Å; E134-G136 PolarHBondContact O-N 3.08Å; G136-V139 PolarHBondContact O-N 2.86Å; G136-F140 WeakPolarHBondContact O-CB 3.27Å; G136-F140 PolarHBondContact O-N 2.92Å
137	R	98.2	Very high	96.2	Very high	1 Å²	1	34.1 Å²	34.1	0%	0.004	17%	0.172	C	C	.	.	H	α-helix	trans	-65.5	-38.8	176.4	-64.2	-67.7	-83.4	-176.1	-6.2	112.2	C53 Y54 L78 W81 Y82 F121 M133 E134 F140 G141	C53-R137 PolarHBondContact O-NH1 3.25Å; Y54-R137 PolarHBondContact O-NH1 2.94Å; Y54-R137 PolarHBondContact O-NH2 3.46Å; L78-R137 HydrophobicContact CB-CG 4.19Å; L78-R137 HydrophobicContact CD2-CG 3.99Å; L78-R137 WeakPolarHBondContact O-CG 3.43Å; L78-R137 PolarHBondContact O-NE 3.38Å; W81-R137 HydrophobicContact CB-CB 4.14Å; Y82-R137 WeakPolarHBondContact CA-O 3.4Å; F121-R137 HydrophobicContact CD2-CG 3.9Å; F121-R137 HydrophobicContact CE2-CG 4.07Å; M133-R137 WeakPolarHBondContact O-CG 3.45Å; M133-R137 PolarHBondContact O-N 2.87Å; E134-R137 PolarHBondContact O-N 3.33Å; E134-R137 VanDerWaalsContact O-N 3.09Å; R137-F140 PolarHBondContact O-N 2.83Å; R137-G141 PolarHBondContact O-N 3.33Å
138	F	98.3	Very high	95.9	Very high	73 Å²	73	31.9 Å²	31.9	32%	0.32	16%	0.157	S	C	.	.	H	α-helix	trans	-61.4	-50.5	173.6	-176.4	-94.4	0	0	0	112	W81 P85 E134 A135 F140 G141 I142	W81-F138 HydrophobicContact CE3-CB 4.22Å; W81-F138 AromaticContact CE3-CD2 3.8Å; W81-F138 HydrophobicContact CE3-CD2 3.8Å; W81-F138 HydrophobicContact CE3-CG 4.36Å; W81-F138 HydrophobicContact CZ3-CD2 4.09Å; W81-F138 VanDerWaalsContact O-CA 3.27Å; W81-F138 WeakPolarHBondContact O-CA 3.5Å; P85-F138 HydrophobicContact CB-CD2 4.27Å; P85-F138 HydrophobicContact CB-CE2 3.89Å; P85-F138 HydrophobicContact CB-CZ 4.17Å; P85-F138 HydrophobicContact CG-CD2 4.04Å; P85-F138 HydrophobicContact CG-CE2 4.16Å; E134-F138 PolarHBondContact O-N 3.42Å; A135-F138 PolarHBondContact O-N 3.42Å; F138-F140 VanDerWaalsContact C-N 3.32Å; F138-F140 PolarHBondContact O-N 2.91Å; F138-G141 PolarHBondContact O-N 2.91Å; F138-G141 VanDerWaalsContact O-N 3.15Å; F138-I142 HydrophobicContact CD1-CD1 4.16Å; F138-I142 HydrophobicContact CE1-CD1 3.86Å; F138-I142 HydrophobicContact CE1-CG1 4.47Å; F138-I142 WeakPolarHBondContact O-CG1 3.42Å; F138-I142 PolarHBondContact O-N 3.22Å
139	V	98.3	Very high	95.4	Very high	31 Å²	31	29.8 Å²	29.8	19%	0.188	15%	0.147	C	C	.	.	H	α-helix	trans	-62.4	-40.4	177.8	175.6	0	0	0	0	111.4	F113 V116 I120 A135 G136 G141 I142	F113-V139 HydrophobicContact CD1-CG1 4.04Å; V116-V139 HydrophobicContact CG1-CG1 4.35Å; I120-V139 HydrophobicContact CD1-CB 4.5Å; I120-V139 HydrophobicContact CD1-CG1 4.41Å; I120-V139 HydrophobicContact CD1-CG2 4.29Å; A135-V139 WeakPolarHBondContact O-CG2 3.42Å; A135-V139 PolarHBondContact O-N 2.92Å; G136-V139 PolarHBondContact O-N 2.86Å; V139-G141 VanDerWaalsContact C-N 3.32Å; V139-G141 PolarHBondContact O-N 3.3Å; V139-I142 WeakPolarHBondContact O-CB 3.47Å; V139-I142 PolarHBondContact O-N 3.39Å
140	F	98.2	Very high	94.9	Very high	1 Å²	1	25.4 Å²	25.4	0%	0.004	13%	0.127	C	C	.	.	H	α-helix	trans	-62	-41.7	175.3	-172	-76.9	0	0	0	111.2	S50 C53 Y82 V114 Q118 G136 R137 F138 I142 G143 G144	S50-F140 WeakPolarHBondContact O-CZ 3.34Å; C53-F140 HydrophobicContact CB-CE2 3.61Å; C53-F140 HydrophobicContact CB-CZ 3.78Å; Y82-F140 AromaticContact CD2-CD1 3.61Å; Y82-F140 HydrophobicContact CD2-CD1 3.61Å; Y82-F140 HydrophobicContact CD2-CE1 4.18Å; Y82-F140 AromaticContact CE2-CD1 3.47Å; Y82-F140 HydrophobicContact CE2-CD1 3.47Å; Y82-F140 VanDerWaalsContact CE2-CD1 3.47Å; Y82-F140 AromaticContact CE2-CE1 3.71Å; Y82-F140 HydrophobicContact CE2-CE1 3.71Å; V114-F140 HydrophobicContact CB-CE2 4.49Å; V114-F140 HydrophobicContact CG1-CD2 4.01Å; V114-F140 HydrophobicContact CG1-CE1 4.44Å; V114-F140 HydrophobicContact CG1-CE2 3.48Å; V114-F140 VanDerWaalsContact CG1-CE2 3.48Å; V114-F140 HydrophobicContact CG1-CZ 3.74Å; V114-F140 WeakPolarHBondContact O-CD2 3.34Å; Q118-F140 HydrophobicContact CB-CD2 3.96Å; Q118-F140 HydrophobicContact CB-CE2 4.06Å; G136-F140 WeakPolarHBondContact O-CB 3.27Å; G136-F140 PolarHBondContact O-N 2.92Å; R137-F140 PolarHBondContact O-N 2.83Å; F138-F140 VanDerWaalsContact C-N 3.32Å; F138-F140 PolarHBondContact O-N 2.91Å; F140-I142 VanDerWaalsContact C-N 3.35Å; F140-I142 PolarHBondContact O-N 2.9Å; F140-G143 PolarHBondContact O-N 3.39Å; F140-G144 PolarHBondContact O-N 2.68Å
141	G	96.2	Very high	94.6	Very high	0 Å²	0	24.2 Å²	24.2	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-57.5	-42.7	177.2	0	0	0	0	0	113.2	Y82 N86 R137 F138 V139 G143 G144	Y82-G141 WeakPolarHBondContact O-CA 3.48Å; N86-G141 PolarHBondContact ND2-O 3.32Å; N86-G141 PolarHBondContact OD1-O 3.04Å; R137-G141 PolarHBondContact O-N 3.33Å; F138-G141 PolarHBondContact O-N 2.91Å; F138-G141 VanDerWaalsContact O-N 3.15Å; V139-G141 VanDerWaalsContact C-N 3.32Å; V139-G141 PolarHBondContact O-N 3.3Å; G141-G143 PolarHBondContact O-N 2.93Å; G141-G144 PolarHBondContact O-N 3.35Å
142	I	95.4	Very high	94	Very high	35 Å²	35	20.1 Å²	20.1	18%	0.179	11%	0.111	C	C	.	.	H	α-helix	trans	-53.4	-41.8	177.2	-65.3	172.1	0	0	0	112	P85 L89 F113 F138 V139 F140 S146	P85-I142 HydrophobicContact CB-CG1 3.73Å; P85-I142 HydrophobicContact CG-CG1 4.3Å; L89-I142 HydrophobicContact CD1-CB 3.85Å; L89-I142 HydrophobicContact CD1-CG1 3.82Å; L89-I142 HydrophobicContact CD1-CG2 3.7Å; F113-I142 HydrophobicContact CD1-CG2 4.14Å; F113-I142 HydrophobicContact CD2-CG2 4.13Å; F113-I142 HydrophobicContact CE1-CG2 4.32Å; F113-I142 HydrophobicContact CE2-CG2 4.31Å; F113-I142 HydrophobicContact CG-CG2 4.05Å; F113-I142 HydrophobicContact CZ-CG2 4.4Å; F138-I142 HydrophobicContact CD1-CD1 4.16Å; F138-I142 HydrophobicContact CE1-CD1 3.86Å; F138-I142 HydrophobicContact CE1-CG1 4.47Å; F138-I142 WeakPolarHBondContact O-CG1 3.42Å; F138-I142 PolarHBondContact O-N 3.22Å; V139-I142 WeakPolarHBondContact O-CB 3.47Å; V139-I142 PolarHBondContact O-N 3.39Å; F140-I142 VanDerWaalsContact C-N 3.35Å; F140-I142 PolarHBondContact O-N 2.9Å; I142-S146 PolarHBondContact O-OG 2.93Å
143	G	93.7	Very high	93.3	Very high	0 Å²	0	19.7 Å²	19.7	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-84.6	-34.2	-179.5	0	0	0	0	0	113.9	F110 V114 F140 G141 L147	F110-G143 WeakPolarHBondContact O-CA 2.99Å; V114-G143 VanDerWaalsContact CG2-C 3.48Å; F140-G143 PolarHBondContact O-N 3.39Å; G141-G143 PolarHBondContact O-N 2.93Å; G143-L147 WeakPolarHBondContact O-CB 3.44Å; G143-L147 PolarHBondContact O-N 3.3Å
144	G	91.8	Very high	92.7	Very high	3 Å²	3	19.8 Å²	19.8	3%	0.031	11%	0.11	C	C	.	.	H	α-helix	trans	-58.4	-59.3	-167.3	0	0	0	0	0	114.4	F140 G141 L147 A148	F140-G144 PolarHBondContact O-N 2.68Å; G141-G144 PolarHBondContact O-N 3.35Å; G144-L147 PolarHBondContact O-N 3.42Å; G144-A148 PolarHBondContact O-N 3.38Å
145	E	90.2	Very high	92.1	Very high	35 Å²	35	18 Å²	18	16%	0.164	10%	0.102	C	C	.	.	H	α-helix	trans	-70.9	-39.8	-178.4	-61.4	-66.8	-179.8	0	0	111.3	N86 L147 A148 V149 Q388 N392	N86-E145 HydrophobicContact CB-CG 3.86Å; N86-E145 VanDerWaalsContact ND2-CG 3.32Å; N86-E145 WeakPolarHBondContact ND2-CG 3.47Å; N86-E145 WeakPolarHBondContact OD1-CB 3.34Å; N86-E145 WeakPolarHBondContact OD1-CG 3.47Å; E145-L147 VanDerWaalsContact C-N 3.28Å; E145-L147 PolarHBondContact O-N 3.4Å; E145-A148 WeakPolarHBondContact O-CB 3.42Å; E145-A148 PolarHBondContact O-N 2.92Å; E145-A148 VanDerWaalsContact O-N 3.13Å; E145-V149 PolarHBondContact O-N 3.06Å; E145-Q388 PolarHBondContact OE2-NE2 3.48Å; E145-N392 PolarHBondContact OE1-ND2 3.37Å
146	S	90.3	Very high	91.3	Very high	2 Å²	2	19.1 Å²	19.1	1%	0.014	11%	0.105	C	C	.	.	H	α-helix	trans	-62.1	-34.8	177.6	-53.2	0	0	0	0	112.5	F110 I142 V149 A150	F110-S146 VanDerWaalsContact CD1-CB 3.45Å; F110-S146 VanDerWaalsContact CG-CB 3.5Å; I142-S146 PolarHBondContact O-OG 2.93Å; S146-V149 PolarHBondContact O-N 3.26Å; S146-A150 PolarHBondContact O-N 3.26Å
147	L	91.9	Very high	90.5	Very high	2 Å²	2	20.2 Å²	20.2	1%	0.01	11%	0.111	C	C	.	.	H	α-helix	trans	-67.6	-38.3	175.1	-177.4	64.1	0	0	0	111.7	L46 T107 F110 V114 G143 G144 E145 A150 Q151	L46-L147 HydrophobicContact CD1-CD1 4.09Å; L46-L147 HydrophobicContact CD2-CD1 4.27Å; L46-L147 HydrophobicContact CG-CD1 4.03Å; T107-L147 HydrophobicContact CG2-CD1 3.93Å; F110-L147 HydrophobicContact CB-CB 4.12Å; F110-L147 HydrophobicContact CB-CD1 4.48Å; V114-L147 HydrophobicContact CG2-CD2 4.22Å; G143-L147 WeakPolarHBondContact O-CB 3.44Å; G143-L147 PolarHBondContact O-N 3.3Å; G144-L147 PolarHBondContact O-N 3.42Å; E145-L147 VanDerWaalsContact C-N 3.28Å; E145-L147 PolarHBondContact O-N 3.4Å; L147-A150 PolarHBondContact O-N 3.23Å; L147-Q151 WeakPolarHBondContact O-CB 3.41Å; L147-Q151 PolarHBondContact O-N 3.11Å
148	A	89.2	Confident	89.9	Confident	13 Å²	13	21.2 Å²	21.2	11%	0.107	12%	0.115	C	C	.	.	H	α-helix	trans	-64.4	-41.1	174.7	0	0	0	0	0	111.4	G144 E145 A150 Q151 N152	G144-A148 PolarHBondContact O-N 3.38Å; E145-A148 WeakPolarHBondContact O-CB 3.42Å; E145-A148 PolarHBondContact O-N 2.92Å; E145-A148 VanDerWaalsContact O-N 3.13Å; A148-A150 VanDerWaalsContact C-N 3.34Å; A148-A150 PolarHBondContact O-N 2.73Å; A148-Q151 PolarHBondContact O-N 3.17Å; A148-N152 PolarHBondContact O-N 2.85Å; A148-N152 PolarHBondContact O-ND2 3.25Å
149	V	86.6	Confident	89.2	Confident	34 Å²	34	18.2 Å²	18.2	21%	0.206	10%	0.102	C	C	.	.	H	α-helix	trans	-58.6	-47.7	172.1	177.5	0	0	0	0	110.4	I97 E145 S146 Q151 N152 T153	I97-V149 HydrophobicContact CD1-CB 4.37Å; I97-V149 HydrophobicContact CD1-CG1 3.99Å; E145-V149 PolarHBondContact O-N 3.06Å; S146-V149 PolarHBondContact O-N 3.26Å; V149-Q151 VanDerWaalsContact C-N 3.34Å; V149-Q151 PolarHBondContact O-N 3.36Å; V149-N152 PolarHBondContact O-N 3.01Å; V149-T153 PolarHBondContact O-N 3.08Å; V149-T153 PolarHBondContact O-OG1 2.95Å; V149-T153 VanDerWaalsContact O-OG1 3.05Å
150	A	88.6	Confident	88.2	Confident	0 Å²	0	23.1 Å²	23.1	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-62.3	-39.1	179.6	0	0	0	0	0	113.3	I97 T107 S146 L147 A148 N152 T153 Y154	I97-A150 HydrophobicContact CD1-CB 3.62Å; T107-A150 HydrophobicContact CG2-CB 4.49Å; T107-A150 VanDerWaalsContact OG1-CB 3.3Å; T107-A150 WeakPolarHBondContact OG1-CB 3.31Å; S146-A150 PolarHBondContact O-N 3.26Å; L147-A150 PolarHBondContact O-N 3.23Å; A148-A150 VanDerWaalsContact C-N 3.34Å; A148-A150 PolarHBondContact O-N 2.73Å; A150-N152 VanDerWaalsContact C-N 3.35Å; A150-T153 PolarHBondContact O-N 2.86Å; A150-Y154 WeakPolarHBondContact O-CD2 3.37Å; A150-Y154 PolarHBondContact O-N 3.38Å
151	Q	89.4	Confident	87.1	Confident	9 Å²	9	26 Å²	26	4%	0.042	15%	0.15	C	C	.	.	H	α-helix	trans	-61.3	-42.7	174.9	-171.7	-178.3	16.5	0	0	111.7	M43 L46 L147 A148 V149 Y154 A155 Q171	M43-Q151 HydrophobicContact CG-CG 4.2Å; M43-Q151 PolarHBondContact O-NE2 3.47Å; L46-Q151 HydrophobicContact CD2-CB 3.96Å; L46-Q151 HydrophobicContact CD2-CG 4.14Å; L147-Q151 WeakPolarHBondContact O-CB 3.41Å; L147-Q151 PolarHBondContact O-N 3.11Å; A148-Q151 PolarHBondContact O-N 3.17Å; V149-Q151 VanDerWaalsContact C-N 3.34Å; V149-Q151 PolarHBondContact O-N 3.36Å; Q151-Y154 WeakPolarHBondContact O-CB 3.36Å; Q151-Y154 PolarHBondContact O-N 2.8Å; Q151-A155 PolarHBondContact O-N 3.17Å; Q151-A155 VanDerWaalsContact O-N 3.12Å; Q151-Q171 HydrophobicContact CG-CG 4.48Å
152	N	85.8	Confident	85.7	Confident	70 Å²	70	35.7 Å²	35.7	37%	0.374	19%	0.192	S	C	.	.	H	α-helix	trans	-66.1	-44.2	176.6	-71	-23.2	0	0	0	111.7	A148 V149 A150 Y154 A155 V156 F168 Q171	A148-N152 PolarHBondContact O-N 2.85Å; A148-N152 PolarHBondContact O-ND2 3.25Å; V149-N152 PolarHBondContact O-N 3.01Å; A150-N152 VanDerWaalsContact C-N 3.35Å; N152-Y154 PolarHBondContact O-N 3.35Å; N152-A155 WeakPolarHBondContact O-CB 3.46Å; N152-A155 PolarHBondContact O-N 3.29Å; N152-A155 VanDerWaalsContact O-N 3.11Å; N152-V156 WeakPolarHBondContact O-CG2 3.47Å; N152-V156 PolarHBondContact O-N 3.18Å; N152-V156 VanDerWaalsContact O-N 3.11Å; N152-F168 HydrophobicContact CB-CE1 3.88Å; N152-F168 WeakPolarHBondContact OD1-CE1 3.44Å; N152-Q171 PolarHBondContact OD1-OE1 2.8Å
153	T	83.3	Confident	84.8	Confident	32 Å²	32	38.2 Å²	38.2	20%	0.196	20%	0.203	C	C	.	.	H	α-helix	trans	-59.7	-37.1	175.9	-50.4	0	0	0	0	111.1	I103 V149 A150 V156 N157	I103-T153 HydrophobicContact CD1-CG2 3.52Å; I103-T153 HydrophobicContact CG1-CG2 4.17Å; V149-T153 PolarHBondContact O-N 3.08Å; V149-T153 PolarHBondContact O-OG1 2.95Å; V149-T153 VanDerWaalsContact O-OG1 3.05Å; A150-T153 PolarHBondContact O-N 2.86Å; T153-V156 PolarHBondContact O-N 3.35Å; T153-N157 WeakPolarHBondContact O-CB 3.19Å; T153-N157 PolarHBondContact O-N 3.42Å
154	Y	86.7	Confident	83.9	Confident	1 Å²	1	39.7 Å²	39.7	0%	0.004	21%	0.211	C	C	.	.	H	α-helix	trans	-64.2	-41.9	176.6	-101.3	-59.1	0	0	0	111.6	M43 I103 R104 T107 A150 Q151 N152 V156 N157 W158 D230	M43-Y154 HydrophobicContact CE-CG 4.46Å; I103-Y154 HydrophobicContact CD1-CD1 3.82Å; I103-Y154 HydrophobicContact CD1-CD2 3.95Å; I103-Y154 HydrophobicContact CD1-CE1 4.16Å; I103-Y154 HydrophobicContact CD1-CE2 4.31Å; I103-Y154 HydrophobicContact CD1-CG 3.69Å; I103-Y154 HydrophobicContact CG1-CD1 4.42Å; I103-Y154 HydrophobicContact CG1-CD2 3.9Å; I103-Y154 HydrophobicContact CG1-CE1 4.39Å; I103-Y154 HydrophobicContact CG1-CE2 3.9Å; I103-Y154 HydrophobicContact CG1-CG 4.17Å; I103-Y154 HydrophobicContact CG2-CE1 4.13Å; R104-Y154 WeakPolarHBondContact CA-OH 3.2Å; R104-Y154 WeakPolarHBondContact CG-OH 3.26Å; T107-Y154 HydrophobicContact CG2-CE2 4.05Å; T107-Y154 WeakPolarHBondContact OG1-CE2 3.29Å; A150-Y154 WeakPolarHBondContact O-CD2 3.37Å; A150-Y154 PolarHBondContact O-N 3.38Å; Q151-Y154 WeakPolarHBondContact O-CB 3.36Å; Q151-Y154 PolarHBondContact O-N 2.8Å; N152-Y154 PolarHBondContact O-N 3.35Å; Y154-V156 PolarHBondContact O-N 3.35Å; Y154-N157 PolarHBondContact O-N 3.35Å; Y154-W158 AromaticContact CD1-CD1 3.97Å; Y154-W158 AromaticContact CD1-NE1 3.96Å; Y154-W158 PolarHBondContact O-N 3.45Å; Y154-D230 HydrophobicContact CE1-CB 3.96Å
155	A	85.6	Confident	83	Confident	0 Å²	0	44.4 Å²	44.4	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-58.7	-48.5	176.1	0	0	0	0	0	111.5	M43 Q151 N152 N157 W158 F159 L164 V167 F168	M43-A155 VanDerWaalsContact SD-CA 3.54Å; M43-A155 HydrophobicContact SD-CB 3.91Å; M43-A155 PolarHBondContact SD-N 3.49Å; M43-A155 VanDerWaalsContact SD-N 3.37Å; Q151-A155 PolarHBondContact O-N 3.17Å; Q151-A155 VanDerWaalsContact O-N 3.12Å; N152-A155 WeakPolarHBondContact O-CB 3.46Å; N152-A155 PolarHBondContact O-N 3.29Å; N152-A155 VanDerWaalsContact O-N 3.11Å; A155-N157 VanDerWaalsContact C-N 3.29Å; A155-N157 PolarHBondContact O-N 2.93Å; A155-W158 PolarHBondContact O-N 3.45Å; A155-F159 WeakPolarHBondContact O-CB 3.45Å; A155-F159 PolarHBondContact O-N 3.12Å; A155-L164 HydrophobicContact CB-CD1 4.04Å; A155-V167 HydrophobicContact CB-CG1 3.63Å; A155-F168 HydrophobicContact CB-CD1 4.5Å; A155-F168 HydrophobicContact CB-CE1 4.05Å; A155-F168 HydrophobicContact CB-CZ 4.4Å
156	V	81.8	Confident	82.5	Confident	59 Å²	59	48.1 Å²	48.1	36%	0.358	26%	0.256	S	S	.	.	H	α-helix	trans	-66.1	-31.3	-179	177.5	0	0	0	0	112.2	N152 T153 Y154 K160 L164 F168	N152-V156 WeakPolarHBondContact O-CG2 3.47Å; N152-V156 PolarHBondContact O-N 3.18Å; N152-V156 VanDerWaalsContact O-N 3.11Å; T153-V156 PolarHBondContact O-N 3.35Å; Y154-V156 PolarHBondContact O-N 3.35Å; V156-K160 WeakPolarHBondContact O-CE 3.32Å; V156-K160 PolarHBondContact O-NZ 3.17Å; V156-L164 HydrophobicContact CG2-CD1 4.2Å; V156-L164 HydrophobicContact CG2-CD2 4.25Å; V156-F168 HydrophobicContact CG2-CE2 4.47Å; V156-F168 HydrophobicContact CG2-CZ 3.82Å
157	N	81.9	Confident	82.2	Confident	24 Å²	24	48.1 Å²	48.1	13%	0.128	26%	0.256	C	S	.	.	H	α-helix	trans	-72.2	-42.1	176.2	-173.4	11.4	0	0	0	111.6	T153 Y154 A155 K239	T153-N157 WeakPolarHBondContact O-CB 3.19Å; T153-N157 PolarHBondContact O-N 3.42Å; Y154-N157 PolarHBondContact O-N 3.35Å; A155-N157 VanDerWaalsContact C-N 3.29Å; A155-N157 PolarHBondContact O-N 2.93Å; N157-K239 PolarHBondContact O-NZ 3.38Å; N157-K239 PolarHBondContact OD1-NZ 2.86Å
158	W	84.1	Confident	81.7	Confident	22 Å²	22	51.4 Å²	51.4	8%	0.083	27%	0.27	C	S	.	.	H	α-helix	trans	-89.8	-23.3	-173	-81.2	81.8	0	0	0	115.4	H35 R36 V39 M43 Y154 A155 D230 A233	H35-W158 AromaticContact CD2-CH2 3.94Å; H35-W158 AromaticContact CD2-CZ3 3.82Å; H35-W158 AromaticContact NE2-CH2 3.75Å; R36-W158 PolarHBondContact NE-O 2.87Å; R36-W158 PolarHBondContact NH2-O 3.3Å; V39-W158 HydrophobicContact CB-CD2 4.48Å; V39-W158 HydrophobicContact CB-CE3 4.25Å; V39-W158 HydrophobicContact CB-CH2 4.46Å; V39-W158 HydrophobicContact CB-CZ3 4.27Å; V39-W158 HydrophobicContact CG1-CD2 3.69Å; V39-W158 HydrophobicContact CG1-CE3 3.94Å; V39-W158 HydrophobicContact CG1-CG 4.08Å; V39-W158 HydrophobicContact CG1-CH2 4.34Å; V39-W158 HydrophobicContact CG1-CZ2 4.1Å; V39-W158 HydrophobicContact CG1-CZ3 4.29Å; V39-W158 HydrophobicContact CG2-CE3 4.18Å; V39-W158 HydrophobicContact CG2-CH2 3.58Å; V39-W158 HydrophobicContact CG2-CZ2 4Å; V39-W158 HydrophobicContact CG2-CZ3 3.7Å; M43-W158 HydrophobicContact CE-CB 4.28Å; M43-W158 HydrophobicContact CE-CG 4.3Å; Y154-W158 AromaticContact CD1-CD1 3.97Å; Y154-W158 AromaticContact CD1-NE1 3.96Å; Y154-W158 PolarHBondContact O-N 3.45Å; A155-W158 PolarHBondContact O-N 3.45Å; W158-D230 HydrophobicContact CZ2-CB 4.19Å; W158-D230 PolarHBondContact NE1-OD1 3.19Å; W158-A233 HydrophobicContact CH2-CB 3.6Å; W158-A233 HydrophobicContact CZ2-CB 3.94Å; W158-A233 HydrophobicContact CZ3-CB 4.48Å
159	F	83.9	Confident	81.3	Confident	10 Å²	10	51.3 Å²	51.3	4%	0.044	27%	0.271	C	S	.	.			trans	-127.9	142.6	-175.6	-58.1	-90.2	0	0	0	110.7	R36 L40 M43 A155 E163 L164 V167	R36-F159 HydrophobicContact CB-CE1 4.13Å; R36-F159 HydrophobicContact CB-CZ 4.27Å; R36-F159 WeakPolarHBondContact O-CZ 3.43Å; L40-F159 HydrophobicContact CB-CE2 4.4Å; L40-F159 HydrophobicContact CB-CZ 3.89Å; L40-F159 HydrophobicContact CD1-CE2 4.44Å; M43-F159 HydrophobicContact CE-CE2 4.25Å; A155-F159 WeakPolarHBondContact O-CB 3.45Å; A155-F159 PolarHBondContact O-N 3.12Å; F159-E163 HydrophobicContact CD1-CB 4.37Å; F159-L164 HydrophobicContact CB-CD1 4.27Å; F159-V167 HydrophobicContact CB-CG2 4.22Å; F159-V167 HydrophobicContact CD1-CG2 3.84Å; F159-V167 HydrophobicContact CD2-CG1 4.24Å; F159-V167 HydrophobicContact CD2-CG2 3.79Å; F159-V167 HydrophobicContact CE1-CG2 4.16Å; F159-V167 HydrophobicContact CE2-CG2 4.1Å; F159-V167 HydrophobicContact CG-CG2 3.67Å; F159-V167 HydrophobicContact CZ-CG2 4.3Å
160	K	77.4	Confident	81.2	Confident	134 Å²	134	53.2 Å²	53.2	58%	0.583	28%	0.28	S	S	*	.			trans	-134.8	154.8	-177.6	-62.7	-63.8	-177.1	-167	0	110.2	V156	V156-K160 WeakPolarHBondContact O-CE 3.32Å; V156-K160 PolarHBondContact O-NZ 3.17Å
161	G	74.2	Confident	81.2	Confident	61 Å²	61	53.5 Å²	53.5	63%	0.629	28%	0.281	S	S	*	.	T	Hydrogen-bonded Turn	trans	61.8	-137.2	176.3	0	0	0	0	0	113.4	E163 L164	G161-E163 PolarHBondContact O-N 3.44Å; G161-L164 WeakPolarHBondContact O-CB 3.21Å; G161-L164 PolarHBondContact O-N 2.68Å
162	K	66.9	Low	80.9	Confident	203 Å²	203	55.4 Å²	55.4	88%	0.883	29%	0.291	S	S	*	.	H	α-helix	trans	-63.6	-22.9	-172.4	-64.6	-176.4	-179.6	178.5	0	114.2	L164	K162-L164 VanDerWaalsContact C-N 3.31Å
163	E	76.4	Confident	81	Confident	89 Å²	89	53 Å²	53	42%	0.416	28%	0.28	S	S	.	.	H	α-helix	trans	-72	-26	179.3	-61.9	179.3	166.2	0	0	112.5	R36 F159 G161 L166 V167	R36-E163 IonicContact CZ-OE2 2.66Å; R36-E163 IonicContact NH1-OE1 2.8Å; R36-E163 IonicContact NH1-OE2 3.17Å; R36-E163 PolarHBondContact NH1-OE2 2.95Å; R36-E163 IonicContact NH2-OE2 2.64Å; R36-E163 PolarHBondContact NH2-OE2 3.49Å; F159-E163 HydrophobicContact CD1-CB 4.37Å; G161-E163 PolarHBondContact O-N 3.44Å; E163-L166 WeakPolarHBondContact O-CB 3.19Å; E163-L166 PolarHBondContact O-N 2.96Å; E163-V167 WeakPolarHBondContact O-CG2 3.5Å; E163-V167 PolarHBondContact O-N 3.39Å; E163-V167 VanDerWaalsContact O-N 3.14Å
164	L	75.8	Confident	81.3	Confident	31 Å²	31	53.2 Å²	53.2	16%	0.162	28%	0.279	C	S	.	.	H	α-helix	trans	-67.2	-40.6	-173.1	-174.8	62.3	0	0	0	112.6	A155 V156 F159 G161 K162 L166 V167 F168	A155-L164 HydrophobicContact CB-CD1 4.04Å; V156-L164 HydrophobicContact CG2-CD1 4.2Å; V156-L164 HydrophobicContact CG2-CD2 4.25Å; F159-L164 HydrophobicContact CB-CD1 4.27Å; G161-L164 WeakPolarHBondContact O-CB 3.21Å; G161-L164 PolarHBondContact O-N 2.68Å; K162-L164 VanDerWaalsContact C-N 3.31Å; L164-L166 VanDerWaalsContact C-N 3.3Å; L164-L166 PolarHBondContact O-N 3.39Å; L164-V167 WeakPolarHBondContact O-CB 3.39Å; L164-V167 PolarHBondContact O-N 3.18Å; L164-V167 VanDerWaalsContact O-N 3.14Å; L164-F168 HydrophobicContact CD1-CD2 4.23Å; L164-F168 HydrophobicContact CD1-CE2 3.74Å; L164-F168 HydrophobicContact CD1-CZ 4.12Å; L164-F168 HydrophobicContact CD2-CE2 3.94Å; L164-F168 HydrophobicContact CG-CD2 3.92Å; L164-F168 HydrophobicContact CG-CE2 3.54Å; L164-F168 HydrophobicContact CG-CZ 4.37Å; L164-F168 WeakPolarHBondContact O-CD2 3.32Å; L164-F168 PolarHBondContact O-N 3.05Å
165	N	73.3	Confident	81.4	Confident	101 Å²	101	53.4 Å²	53.4	54%	0.54	28%	0.281	S	S	.	.	H	α-helix	trans	-63.4	-37.8	177.6	-68	6.9	0	0	0	111.6	V167 G169	N165-V167 VanDerWaalsContact C-N 3.34Å; N165-G169 PolarHBondContact O-N 3.13Å
166	L	79.7	Confident	81.6	Confident	113 Å²	113	54.2 Å²	54.2	59%	0.592	28%	0.284	S	S	*	.	H	α-helix	trans	-63.8	-41.7	174.8	179.1	65.7	0	0	0	111	E163 L164 G169 L170	E163-L166 WeakPolarHBondContact O-CB 3.19Å; E163-L166 PolarHBondContact O-N 2.96Å; L164-L166 VanDerWaalsContact C-N 3.3Å; L164-L166 PolarHBondContact O-N 3.39Å; L166-G169 PolarHBondContact O-N 3.36Å; L166-L170 HydrophobicContact CD1-CD1 4.33Å; L166-L170 HydrophobicContact CD1-CG 4.42Å; L166-L170 HydrophobicContact CG-CD1 4.08Å; L166-L170 WeakPolarHBondContact O-CG 3.16Å; L166-L170 PolarHBondContact O-N 3.49Å
167	V	84.6	Confident	82.1	Confident	3 Å²	3	54.7 Å²	54.7	2%	0.018	28%	0.284	C	S	.	.	H	α-helix	trans	-63.3	-48.2	178.3	171	0	0	0	0	111.4	L40 M43 A155 F159 E163 L164 N165 G169 L170 Q171	L40-V167 HydrophobicContact CD1-CB 4.12Å; L40-V167 HydrophobicContact CD1-CG1 3.62Å; L40-V167 HydrophobicContact CD1-CG2 3.76Å; L40-V167 HydrophobicContact CD2-CG2 4.21Å; M43-V167 HydrophobicContact SD-CG1 4.44Å; A155-V167 HydrophobicContact CB-CG1 3.63Å; F159-V167 HydrophobicContact CB-CG2 4.22Å; F159-V167 HydrophobicContact CD1-CG2 3.84Å; F159-V167 HydrophobicContact CD2-CG1 4.24Å; F159-V167 HydrophobicContact CD2-CG2 3.79Å; F159-V167 HydrophobicContact CE1-CG2 4.16Å; F159-V167 HydrophobicContact CE2-CG2 4.1Å; F159-V167 HydrophobicContact CG-CG2 3.67Å; F159-V167 HydrophobicContact CZ-CG2 4.3Å; E163-V167 WeakPolarHBondContact O-CG2 3.5Å; E163-V167 PolarHBondContact O-N 3.39Å; E163-V167 VanDerWaalsContact O-N 3.14Å; L164-V167 WeakPolarHBondContact O-CB 3.39Å; L164-V167 PolarHBondContact O-N 3.18Å; L164-V167 VanDerWaalsContact O-N 3.14Å; N165-V167 VanDerWaalsContact C-N 3.34Å; V167-G169 VanDerWaalsContact C-N 3.3Å; V167-G169 PolarHBondContact O-N 3.05Å; V167-L170 PolarHBondContact O-N 2.9Å; V167-Q171 HydrophobicContact CG1-CG 4.38Å; V167-Q171 VanDerWaalsContact O-CG 3.31Å; V167-Q171 WeakPolarHBondContact O-CG 3.34Å; V167-Q171 PolarHBondContact O-N 3.34Å
168	F	81.3	Confident	82.7	Confident	70 Å²	70	53.6 Å²	53.6	31%	0.307	28%	0.278	S	S	.	.	H	α-helix	trans	-60.2	-41.4	175.6	-75.4	-52.1	0	0	0	112.2	N152 A155 V156 L164 Q171 L172	N152-F168 HydrophobicContact CB-CE1 3.88Å; N152-F168 WeakPolarHBondContact OD1-CE1 3.44Å; A155-F168 HydrophobicContact CB-CD1 4.5Å; A155-F168 HydrophobicContact CB-CE1 4.05Å; A155-F168 HydrophobicContact CB-CZ 4.4Å; V156-F168 HydrophobicContact CG2-CE2 4.47Å; V156-F168 HydrophobicContact CG2-CZ 3.82Å; L164-F168 HydrophobicContact CD1-CD2 4.23Å; L164-F168 HydrophobicContact CD1-CE2 3.74Å; L164-F168 HydrophobicContact CD1-CZ 4.12Å; L164-F168 HydrophobicContact CD2-CE2 3.94Å; L164-F168 HydrophobicContact CG-CD2 3.92Å; L164-F168 HydrophobicContact CG-CE2 3.54Å; L164-F168 HydrophobicContact CG-CZ 4.37Å; L164-F168 WeakPolarHBondContact O-CD2 3.32Å; L164-F168 PolarHBondContact O-N 3.05Å; F168-Q171 PolarHBondContact O-N 3.01Å; F168-L172 WeakPolarHBondContact O-CB 3.35Å; F168-L172 PolarHBondContact O-N 3.38Å
169	G	80.2	Confident	83.2	Confident	12 Å²	12	52.6 Å²	52.6	12%	0.124	28%	0.275	C	S	.	.	H	α-helix	trans	-58	-50.1	174.3	0	0	0	0	0	112.3	N165 L166 V167 L172 S173	N165-G169 PolarHBondContact O-N 3.13Å; L166-G169 PolarHBondContact O-N 3.36Å; V167-G169 VanDerWaalsContact C-N 3.3Å; V167-G169 PolarHBondContact O-N 3.05Å; G169-L172 PolarHBondContact O-N 3.3Å; G169-S173 PolarHBondContact O-N 3.39Å; G169-S173 PolarHBondContact O-OG 3.11Å
170	L	84.7	Confident	83.6	Confident	74 Å²	74	52.9 Å²	52.9	39%	0.387	28%	0.277	S	S	.	.	H	α-helix	trans	-64.1	-41	179.4	-74.3	170.1	0	0	0	113	L40 L166 V167 S173 M174	L40-L170 HydrophobicContact CD2-CD1 3.99Å; L166-L170 HydrophobicContact CD1-CD1 4.33Å; L166-L170 HydrophobicContact CD1-CG 4.42Å; L166-L170 HydrophobicContact CG-CD1 4.08Å; L166-L170 WeakPolarHBondContact O-CG 3.16Å; L166-L170 PolarHBondContact O-N 3.49Å; V167-L170 PolarHBondContact O-N 2.9Å; L170-S173 PolarHBondContact O-N 3.02Å; L170-M174 WeakPolarHBondContact O-CB 3.17Å; L170-M174 PolarHBondContact O-N 2.71Å
171	Q	87.3	Confident	84.4	Confident	5 Å²	5	48.8 Å²	48.8	2%	0.023	26%	0.263	C	S	.	.	H	α-helix	trans	-61.6	-47.6	175.8	-73.8	177.5	-2.1	0	0	111.3	M43 Q151 N152 V167 F168 M174 A175	M43-Q171 VanDerWaalsContact CG-NE2 3.27Å; M43-Q171 PolarHBondContact SD-NE2 3.11Å; Q151-Q171 HydrophobicContact CG-CG 4.48Å; N152-Q171 PolarHBondContact OD1-OE1 2.8Å; V167-Q171 HydrophobicContact CG1-CG 4.38Å; V167-Q171 VanDerWaalsContact O-CG 3.31Å; V167-Q171 WeakPolarHBondContact O-CG 3.34Å; V167-Q171 PolarHBondContact O-N 3.34Å; F168-Q171 PolarHBondContact O-N 3.01Å; Q171-M174 PolarHBondContact O-N 3.47Å; Q171-M174 VanDerWaalsContact O-N 3.17Å; Q171-A175 PolarHBondContact O-N 3.27Å
172	L	83.6	Confident	85.5	Confident	50 Å²	50	45.9 Å²	45.9	26%	0.262	23%	0.233	S	C	.	.	H	α-helix	trans	-62.6	-44.3	177.7	-175.2	61.6	0	0	0	111.2	F168 G169 M174 A175 R176	F168-L172 WeakPolarHBondContact O-CB 3.35Å; F168-L172 PolarHBondContact O-N 3.38Å; G169-L172 PolarHBondContact O-N 3.3Å; L172-M174 VanDerWaalsContact C-N 3.26Å; L172-M174 PolarHBondContact O-N 3.36Å; L172-A175 WeakPolarHBondContact O-CB 3.23Å; L172-A175 PolarHBondContact O-N 2.91Å; L172-R176 WeakPolarHBondContact O-CG 3.34Å; L172-R176 PolarHBondContact O-N 3.28Å
173	S	87.7	Confident	86.6	Confident	19 Å²	19	36.2 Å²	36.2	13%	0.133	19%	0.191	C	C	.	.	H	α-helix	trans	-57.7	-40.4	174.3	-60.2	0	0	0	0	111.7	G169 L170 R176 L177 A308	G169-S173 PolarHBondContact O-N 3.39Å; G169-S173 PolarHBondContact O-OG 3.11Å; L170-S173 PolarHBondContact O-N 3.02Å; S173-R176 PolarHBondContact O-N 3.29Å; S173-L177 WeakPolarHBondContact O-CG 3.46Å; S173-L177 PolarHBondContact O-N 3.42Å; S173-A308 PolarHBondContact OG-O 3.28Å
174	M	89.4	Confident	87.3	Confident	37 Å²	37	35.3 Å²	35.3	18%	0.182	19%	0.189	C	C	.	.	H	α-helix	trans	-69.4	-36.8	178.8	-163.7	48.7	44	0	0	113.2	C44 F45 F48 L170 Q171 L172 L177 G178	C44-M174 HydrophobicContact CB-CB 4.12Å; C44-M174 HydrophobicContact CB-CG 4.14Å; C44-M174 VanDerWaalsContact O-CG 3.25Å; C44-M174 WeakPolarHBondContact O-CG 3.4Å; F45-M174 HydrophobicContact CD1-CG 4.45Å; F45-M174 HydrophobicContact CD1-SD 4.36Å; F45-M174 HydrophobicContact CE1-SD 3.94Å; F45-M174 HydrophobicContact CZ-SD 4.45Å; F48-M174 HydrophobicContact CD2-CG 4.36Å; F48-M174 HydrophobicContact CD2-SD 4Å; F48-M174 HydrophobicContact CE2-SD 4.45Å; L170-M174 WeakPolarHBondContact O-CB 3.17Å; L170-M174 PolarHBondContact O-N 2.71Å; Q171-M174 PolarHBondContact O-N 3.47Å; Q171-M174 VanDerWaalsContact O-N 3.17Å; L172-M174 VanDerWaalsContact C-N 3.26Å; L172-M174 PolarHBondContact O-N 3.36Å; M174-L177 HydrophobicContact CE-CD1 3.34Å; M174-L177 PolarHBondContact O-N 3.23Å; M174-L177 HydrophobicContact SD-CB 4.13Å; M174-L177 HydrophobicContact SD-CD1 4.04Å; M174-G178 PolarHBondContact O-N 3.01Å
175	A	89.4	Confident	88.2	Confident	5 Å²	5	37.4 Å²	37.4	4%	0.041	20%	0.2	C	C	.	.	H	α-helix	trans	-57.2	-48.2	170.4	0	0	0	0	0	111.6	Y51 Q171 L172 L177 G178 S179	Y51-A175 VanDerWaalsContact CB-O 3.27Å; Y51-A175 WeakPolarHBondContact CB-O 3.4Å; Y51-A175 HydrophobicContact CD1-CB 3.92Å; Y51-A175 HydrophobicContact CD2-CB 3.34Å; Y51-A175 HydrophobicContact CE1-CB 3.86Å; Y51-A175 HydrophobicContact CE2-CB 3.3Å; Y51-A175 HydrophobicContact CG-CB 3.67Å; Q171-A175 PolarHBondContact O-N 3.27Å; L172-A175 WeakPolarHBondContact O-CB 3.23Å; L172-A175 PolarHBondContact O-N 2.91Å; A175-L177 VanDerWaalsContact C-N 3.31Å; A175-L177 PolarHBondContact O-N 3.43Å; A175-G178 PolarHBondContact O-N 3.39Å; A175-S179 PolarHBondContact O-N 3.07Å
176	R	90.4	Very high	89.3	Confident	16 Å²	16	32.7 Å²	32.7	6%	0.06	18%	0.175	C	C	.	.	H	α-helix	trans	-63	-36	176	-59.2	-52.2	169.6	-168.3	-0.1	113.3	L172 S173 S179 T180 A308 Y360	L172-R176 WeakPolarHBondContact O-CG 3.34Å; L172-R176 PolarHBondContact O-N 3.28Å; S173-R176 PolarHBondContact O-N 3.29Å; R176-S179 PolarHBondContact O-N 2.97Å; R176-T180 WeakPolarHBondContact O-CB 3.48Å; R176-T180 PolarHBondContact O-N 3.47Å; R176-T180 PolarHBondContact O-OG1 3.13Å; R176-A308 HydrophobicContact CB-CB 3.67Å; R176-A308 HydrophobicContact CG-CB 4.3Å; R176-Y360 VanDerWaalsContact CZ-CZ 3.5Å; R176-Y360 VanDerWaalsContact NH1-CE1 3.3Å; R176-Y360 PolarHBondContact NH1-OH 3.34Å; R176-Y360 PolarHBondContact NH2-OH 3.4Å
177	L	92.2	Very high	89.9	Confident	70 Å²	70	27.7 Å²	27.7	37%	0.366	15%	0.15	S	C	.	.	H	α-helix	trans	-64.7	-40.6	175.2	-75.6	168.5	0	0	0	111.1	S173 M174 A175 S179 T180 V181	S173-L177 WeakPolarHBondContact O-CG 3.46Å; S173-L177 PolarHBondContact O-N 3.42Å; M174-L177 HydrophobicContact CE-CD1 3.34Å; M174-L177 PolarHBondContact O-N 3.23Å; M174-L177 HydrophobicContact SD-CB 4.13Å; M174-L177 HydrophobicContact SD-CD1 4.04Å; A175-L177 VanDerWaalsContact C-N 3.31Å; A175-L177 PolarHBondContact O-N 3.43Å; L177-S179 PolarHBondContact O-N 3.46Å; L177-T180 WeakPolarHBondContact O-CB 3.35Å; L177-T180 PolarHBondContact O-N 3.14Å; L177-V181 WeakPolarHBondContact O-CB 3.37Å; L177-V181 WeakPolarHBondContact O-CG2 3.11Å; L177-V181 PolarHBondContact O-N 3.22Å
178	G	94.2	Very high	90.4	Very high	0 Å²	0	35 Å²	35	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-52.7	-53.6	173.2	0	0	0	0	0	112.6	F48 F52 M174 A175 T180 V181 N182	F48-G178 VanDerWaalsContact CE2-CA 3.48Å; F52-G178 WeakPolarHBondContact CD2-O 3.05Å; M174-G178 PolarHBondContact O-N 3.01Å; A175-G178 PolarHBondContact O-N 3.39Å; G178-T180 PolarHBondContact O-N 3.4Å; G178-V181 PolarHBondContact O-N 3.44Å; G178-N182 WeakPolarHBondContact O-CB 3.25Å; G178-N182 PolarHBondContact O-N 3.42Å
179	S	93.9	Very high	91.2	Very high	2 Å²	2	32.3 Å²	32.3	1%	0.014	17%	0.167	C	C	.	.	H	α-helix	trans	-59.1	-42.1	175.9	-64.3	0	0	0	0	113.5	Y51 D55 A175 R176 L177 N182 M183 Y304	Y51-S179 PolarHBondContact O-OG 2.93Å; D55-S179 WeakPolarHBondContact OD2-CB 3.25Å; D55-S179 PolarHBondContact OD2-OG 3.14Å; A175-S179 PolarHBondContact O-N 3.07Å; R176-S179 PolarHBondContact O-N 2.97Å; L177-S179 PolarHBondContact O-N 3.46Å; S179-N182 WeakPolarHBondContact O-CB 3.23Å; S179-N182 PolarHBondContact O-N 3.12Å; S179-M183 WeakPolarHBondContact O-CG 3.49Å; S179-M183 PolarHBondContact O-N 3.32Å; S179-M183 VanDerWaalsContact O-N 3.09Å; S179-Y304 VanDerWaalsContact CB-CD2 3.45Å
180	T	93.1	Very high	92	Very high	15 Å²	15	32.5 Å²	32.5	9%	0.092	16%	0.164	C	C	.	.	H	α-helix	trans	-62.4	-48.8	178.5	-63.4	0	0	0	0	111.6	R176 L177 G178 N182 M183 N184 Y304 I305	R176-T180 WeakPolarHBondContact O-CB 3.48Å; R176-T180 PolarHBondContact O-N 3.47Å; R176-T180 PolarHBondContact O-OG1 3.13Å; L177-T180 WeakPolarHBondContact O-CB 3.35Å; L177-T180 PolarHBondContact O-N 3.14Å; G178-T180 PolarHBondContact O-N 3.4Å; T180-N182 VanDerWaalsContact C-N 3.3Å; T180-N182 PolarHBondContact O-N 2.98Å; T180-M183 PolarHBondContact O-N 3.23Å; T180-N184 PolarHBondContact O-N 3.26Å; T180-N184 PolarHBondContact O-ND2 2.75Å; T180-Y304 VanDerWaalsContact OG1-CB 3.31Å; T180-Y304 WeakPolarHBondContact OG1-CB 3.38Å; T180-I305 HydrophobicContact CG2-CD1 3.92Å; T180-I305 HydrophobicContact CG2-CG1 3.34Å
181	V	95.1	Very high	92.5	Very high	48 Å²	48	31.5 Å²	31.5	29%	0.291	16%	0.163	S	C	.	.	H	α-helix	trans	-62.1	-43.6	-179.7	176.5	0	0	0	0	109.1	F48 F52 L177 G178 M183 N184 I185	F48-V181 HydrophobicContact CZ-CB 4.46Å; F52-V181 HydrophobicContact CD2-CB 4.36Å; F52-V181 HydrophobicContact CD2-CG1 4.28Å; F52-V181 HydrophobicContact CE2-CB 4.29Å; F52-V181 HydrophobicContact CE2-CG1 3.83Å; L177-V181 WeakPolarHBondContact O-CB 3.37Å; L177-V181 WeakPolarHBondContact O-CG2 3.11Å; L177-V181 PolarHBondContact O-N 3.22Å; G178-V181 PolarHBondContact O-N 3.44Å; V181-M183 PolarHBondContact O-N 3.49Å; V181-N184 PolarHBondContact O-N 2.76Å; V181-I185 HydrophobicContact CG1-CD1 3.4Å; V181-I185 VanDerWaalsContact CG1-CD1 3.4Å; V181-I185 HydrophobicContact CG1-CG1 4.09Å; V181-I185 VanDerWaalsContact O-CB 3.26Å; V181-I185 WeakPolarHBondContact O-CB 3.4Å; V181-I185 WeakPolarHBondContact O-CG1 3.48Å; V181-I185 PolarHBondContact O-N 2.99Å
182	N	95.9	Very high	92.9	Very high	0 Å²	0	36.8 Å²	36.8	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-55	-53.8	176	175.3	67.1	0	0	0	112.7	F52 D55 N56 A59 G178 S179 T180 N184 I185 M186	F52-N182 HydrophobicContact CB-CB 4.44Å; F52-N182 HydrophobicContact CD1-CB 3.97Å; F52-N182 HydrophobicContact CD2-CB 3.72Å; F52-N182 HydrophobicContact CE1-CB 4.05Å; F52-N182 WeakPolarHBondContact CE1-OD1 3.24Å; F52-N182 VanDerWaalsContact CE2-CA 3.49Å; F52-N182 HydrophobicContact CE2-CB 3.84Å; F52-N182 HydrophobicContact CG-CB 3.79Å; F52-N182 HydrophobicContact CZ-CB 4Å; F52-N182 WeakPolarHBondContact O-CB 3.43Å; F52-N182 PolarHBondContact O-ND2 3.01Å; F52-N182 PolarHBondContact O-OD1 2.91Å; D55-N182 WeakPolarHBondContact CB-ND2 3.48Å; D55-N182 PolarHBondContact O-ND2 3.2Å; N56-N182 PolarHBondContact N-ND2 2.92Å; N56-N182 PolarHBondContact OD1-OD1 3.38Å; A59-N182 VanDerWaalsContact CB-ND2 3.33Å; A59-N182 WeakPolarHBondContact CB-ND2 3.38Å; G178-N182 WeakPolarHBondContact O-CB 3.25Å; G178-N182 PolarHBondContact O-N 3.42Å; S179-N182 WeakPolarHBondContact O-CB 3.23Å; S179-N182 PolarHBondContact O-N 3.12Å; T180-N182 VanDerWaalsContact C-N 3.3Å; T180-N182 PolarHBondContact O-N 2.98Å; N182-N184 PolarHBondContact O-N 2.83Å; N182-I185 PolarHBondContact O-N 3.47Å; N182-M186 WeakPolarHBondContact O-CB 3.45Å; N182-M186 WeakPolarHBondContact O-CG 3.43Å; N182-M186 PolarHBondContact O-N 3.44Å; N182-M186 WeakPolarHBondContact OD1-CG 3.41Å
183	M	90.8	Very high	93.6	Very high	0 Å²	0	35 Å²	35	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-59.2	-32.4	-177.9	-71.1	-71.8	164.9	0	0	113.4	D55 A58 A59 S179 T180 V181 I278 R297	D55-M183 HydrophobicContact CB-CE 3.6Å; A58-M183 HydrophobicContact CB-CE 3.32Å; A58-M183 HydrophobicContact CB-SD 4.28Å; A59-M183 HydrophobicContact CB-CE 4.46Å; A59-M183 HydrophobicContact CB-SD 3.88Å; S179-M183 WeakPolarHBondContact O-CG 3.49Å; S179-M183 PolarHBondContact O-N 3.32Å; S179-M183 VanDerWaalsContact O-N 3.09Å; T180-M183 PolarHBondContact O-N 3.23Å; V181-M183 PolarHBondContact O-N 3.49Å; M183-I278 HydrophobicContact CE-CG2 4.37Å; M183-R297 WeakPolarHBondContact O-CD 3.33Å
184	N	91.8	Very high	94	Very high	71 Å²	71	35 Å²	35	38%	0.38	18%	0.179	S	C	.	.	H	α-helix	trans	-91.5	-27.5	-177.3	-72.4	-81.1	0	0	0	113.1	T180 V181 N182 S301	T180-N184 PolarHBondContact O-N 3.26Å; T180-N184 PolarHBondContact O-ND2 2.75Å; V181-N184 PolarHBondContact O-N 2.76Å; N182-N184 PolarHBondContact O-N 2.83Å; N184-S301 WeakPolarHBondContact ND2-CB 3.22Å; N184-S301 PolarHBondContact ND2-OG 3.31Å
185	I	94.3	Very high	94.3	Very high	75 Å²	75	39 Å²	39	39%	0.385	20%	0.204	S	C	.	.	H	α-helix	trans	-97.7	-37.5	-173.2	-64.6	-170.8	0	0	0	112.9	V181 N182 G187 W188 V189	V181-I185 HydrophobicContact CG1-CD1 3.4Å; V181-I185 VanDerWaalsContact CG1-CD1 3.4Å; V181-I185 HydrophobicContact CG1-CG1 4.09Å; V181-I185 VanDerWaalsContact O-CB 3.26Å; V181-I185 WeakPolarHBondContact O-CB 3.4Å; V181-I185 WeakPolarHBondContact O-CG1 3.48Å; V181-I185 PolarHBondContact O-N 2.99Å; N182-I185 PolarHBondContact O-N 3.47Å; I185-G187 VanDerWaalsContact C-N 3.34Å; I185-G187 PolarHBondContact O-N 3.16Å; I185-W188 WeakPolarHBondContact O-CA 3.29Å; I185-W188 WeakPolarHBondContact O-CB 3.46Å; I185-W188 PolarHBondContact O-N 2.75Å; I185-V189 HydrophobicContact CG2-CG2 3.65Å; I185-V189 PolarHBondContact O-N 3.42Å
186	M	95.6	Very high	94.6	Very high	2 Å²	2	42.9 Å²	42.9	1%	0.01	24%	0.237	C	C	.	.	H	α-helix	trans	-62.8	-37	-169.1	-76.6	-55.1	-65.5	0	0	114	F52 A59 L60 N182 W188 V189 Y190 S208 A212	F52-M186 HydrophobicContact CE1-CG 4.03Å; F52-M186 HydrophobicContact CE1-SD 3.77Å; F52-M186 HydrophobicContact CZ-CG 4.04Å; F52-M186 HydrophobicContact CZ-SD 3.86Å; A59-M186 HydrophobicContact CB-CB 4.01Å; L60-M186 HydrophobicContact CD1-CB 4.42Å; L60-M186 HydrophobicContact CD1-CE 3.74Å; L60-M186 HydrophobicContact CD2-CB 4.15Å; L60-M186 HydrophobicContact CG-CB 4.07Å; N182-M186 WeakPolarHBondContact O-CB 3.45Å; N182-M186 WeakPolarHBondContact O-CG 3.43Å; N182-M186 PolarHBondContact O-N 3.44Å; N182-M186 WeakPolarHBondContact OD1-CG 3.41Å; M186-W188 VanDerWaalsContact C-N 3.29Å; M186-W188 PolarHBondContact O-N 3.21Å; M186-V189 PolarHBondContact O-N 3.27Å; M186-Y190 PolarHBondContact O-N 3.17Å; M186-S208 WeakPolarHBondContact CE-O 3.4Å; M186-A212 HydrophobicContact CE-CB 3.94Å; M186-A212 HydrophobicContact SD-CB 3.95Å
187	G	93.5	Very high	94.7	Very high	8 Å²	8	44.8 Å²	44.8	8%	0.082	25%	0.25	C	S	.	.	H	α-helix	trans	-62.3	-35.7	173.7	0	0	0	0	0	113.1	I185 S191	I185-G187 VanDerWaalsContact C-N 3.34Å; I185-G187 PolarHBondContact O-N 3.16Å; G187-S191 PolarHBondContact O-N 2.86Å; G187-S191 VanDerWaalsContact O-N 3.12Å
188	W	94.6	Very high	94.7	Very high	155 Å²	155	44.7 Å²	44.7	59%	0.587	27%	0.266	S	S	*	.	H	α-helix	trans	-69.9	-43.4	173.9	175.8	89.6	0	0	0	111.4	I185 M186 Y190 S191 K192	I185-W188 WeakPolarHBondContact O-CA 3.29Å; I185-W188 WeakPolarHBondContact O-CB 3.46Å; I185-W188 PolarHBondContact O-N 2.75Å; M186-W188 VanDerWaalsContact C-N 3.29Å; M186-W188 PolarHBondContact O-N 3.21Å; W188-Y190 VanDerWaalsContact C-N 3.33Å; W188-Y190 PolarHBondContact O-N 3.21Å; W188-S191 PolarHBondContact O-N 3.18Å; W188-S191 VanDerWaalsContact O-N 3.17Å; W188-S191 PolarHBondContact O-OG 3.14Å; W188-K192 HydrophobicContact CD2-CG 4.08Å; W188-K192 HydrophobicContact CE3-CG 4.44Å; W188-K192 HydrophobicContact CH2-CG 4.15Å; W188-K192 HydrophobicContact CZ2-CD 4.3Å; W188-K192 HydrophobicContact CZ2-CG 3.76Å; W188-K192 HydrophobicContact CZ3-CG 4.47Å; W188-K192 PolarHBondContact O-N 3.27Å
189	V	96.8	Very high	94.6	Very high	14 Å²	14	48 Å²	48	9%	0.085	29%	0.289	C	S	.	.	H	α-helix	trans	-56.1	-50.5	175.6	172.5	0	0	0	0	109.9	I185 M186 S191 K192 V193 I211	I185-V189 HydrophobicContact CG2-CG2 3.65Å; I185-V189 PolarHBondContact O-N 3.42Å; M186-V189 PolarHBondContact O-N 3.27Å; V189-S191 VanDerWaalsContact C-N 3.32Å; V189-S191 PolarHBondContact O-N 3.47Å; V189-K192 PolarHBondContact O-N 3.2Å; V189-K192 VanDerWaalsContact O-N 3.13Å; V189-V193 HydrophobicContact CG1-CG2 4.25Å; V189-V193 WeakPolarHBondContact O-CG2 3.34Å; V189-V193 PolarHBondContact O-N 3.18Å; V189-I211 HydrophobicContact CG1-CB 4.34Å; V189-I211 HydrophobicContact CG1-CD1 3.96Å; V189-I211 HydrophobicContact CG1-CG2 4.23Å
190	Y	96.9	Very high	94.5	Very high	16 Å²	16	52.1 Å²	52.1	6%	0.063	32%	0.318	C	S	.	.	H	α-helix	trans	-55.6	-47	177	-177	-78.7	0	0	0	111.8	L60 Q63 D67 M186 W188 K192 V193 A194 S200 G201 T204 L205 S208	L60-Y190 HydrophobicContact CD2-CD2 4.46Å; L60-Y190 HydrophobicContact CD2-CG 4.4Å; Q63-Y190 HydrophobicContact CB-CD2 4.21Å; Q63-Y190 HydrophobicContact CB-CE2 3.87Å; Q63-Y190 HydrophobicContact CG-CD1 3.93Å; Q63-Y190 HydrophobicContact CG-CD2 3.93Å; Q63-Y190 HydrophobicContact CG-CE1 3.84Å; Q63-Y190 HydrophobicContact CG-CE2 3.78Å; Q63-Y190 HydrophobicContact CG-CG 4.01Å; D67-Y190 VanDerWaalsContact CG-OH 3.28Å; D67-Y190 PolarHBondContact OD1-OH 3.22Å; D67-Y190 WeakPolarHBondContact OD2-CE2 3.14Å; D67-Y190 VanDerWaalsContact OD2-CZ 3.22Å; D67-Y190 PolarHBondContact OD2-OH 3.41Å; M186-Y190 PolarHBondContact O-N 3.17Å; W188-Y190 VanDerWaalsContact C-N 3.33Å; W188-Y190 PolarHBondContact O-N 3.21Å; Y190-K192 VanDerWaalsContact C-N 3.29Å; Y190-K192 PolarHBondContact O-N 2.91Å; Y190-V193 PolarHBondContact O-N 3.18Å; Y190-A194 HydrophobicContact CE1-CB 4.32Å; Y190-A194 WeakPolarHBondContact O-CB 3.45Å; Y190-A194 PolarHBondContact O-N 3.33Å; Y190-S200 WeakPolarHBondContact OH-CB 3.38Å; Y190-G201 PolarHBondContact OH-N 2.86Å; Y190-T204 HydrophobicContact CD1-CG2 4.28Å; Y190-T204 HydrophobicContact CD2-CG2 3.97Å; Y190-T204 HydrophobicContact CE1-CG2 3.93Å; Y190-T204 HydrophobicContact CE2-CG2 3.65Å; Y190-T204 HydrophobicContact CG-CG2 4.27Å; Y190-L205 HydrophobicContact CE2-CB 4.11Å; Y190-L205 HydrophobicContact CE2-CD1 4.44Å; Y190-S208 WeakPolarHBondContact CA-OG 3.35Å
191	S	95.3	Very high	94.5	Very high	53 Å²	53	52.2 Å²	52.2	37%	0.371	32%	0.322	S	S	.	.	H	α-helix	trans	-61.7	-36.6	-179.9	74.1	0	0	0	0	113.1	G187 W188 V189 V195	G187-S191 PolarHBondContact O-N 2.86Å; G187-S191 VanDerWaalsContact O-N 3.12Å; W188-S191 PolarHBondContact O-N 3.18Å; W188-S191 VanDerWaalsContact O-N 3.17Å; W188-S191 PolarHBondContact O-OG 3.14Å; V189-S191 VanDerWaalsContact C-N 3.32Å; V189-S191 PolarHBondContact O-N 3.47Å; S191-V195 WeakPolarHBondContact O-CG2 3.3Å; S191-V195 PolarHBondContact O-N 2.84Å
192	K	97	Very high	94.6	Very high	117 Å²	117	53 Å²	53	51%	0.509	32%	0.322	S	S	.	.	H	α-helix	trans	-72.5	-39.7	177.3	-69	-62.7	-175.4	-178.7	0	112.2	W188 V189 Y190 A194 V195 A196	W188-K192 HydrophobicContact CD2-CG 4.08Å; W188-K192 HydrophobicContact CE3-CG 4.44Å; W188-K192 HydrophobicContact CH2-CG 4.15Å; W188-K192 HydrophobicContact CZ2-CD 4.3Å; W188-K192 HydrophobicContact CZ2-CG 3.76Å; W188-K192 HydrophobicContact CZ3-CG 4.47Å; W188-K192 PolarHBondContact O-N 3.27Å; V189-K192 PolarHBondContact O-N 3.2Å; V189-K192 VanDerWaalsContact O-N 3.13Å; Y190-K192 VanDerWaalsContact C-N 3.29Å; Y190-K192 PolarHBondContact O-N 2.91Å; K192-A194 VanDerWaalsContact C-N 3.35Å; K192-V195 PolarHBondContact O-N 3.42Å; K192-A196 PolarHBondContact O-N 2.95Å
193	V	97	Very high	94.6	Very high	13 Å²	13	55.1 Å²	55.1	8%	0.079	34%	0.335	C	S	.	.	H	α-helix	trans	-64.6	-42.4	174.5	176.1	0	0	0	0	110.3	V189 Y190 V195 A196 V197 T204 I207 I211	V189-V193 HydrophobicContact CG1-CG2 4.25Å; V189-V193 WeakPolarHBondContact O-CG2 3.34Å; V189-V193 PolarHBondContact O-N 3.18Å; Y190-V193 PolarHBondContact O-N 3.18Å; V193-V195 VanDerWaalsContact C-N 3.28Å; V193-V195 PolarHBondContact O-N 3.31Å; V193-A196 PolarHBondContact O-N 2.86Å; V193-V197 HydrophobicContact CG1-CG2 3.89Å; V193-V197 WeakPolarHBondContact O-CB 3.44Å; V193-V197 WeakPolarHBondContact O-CG2 3.29Å; V193-V197 PolarHBondContact O-N 2.93Å; V193-T204 HydrophobicContact CB-CG2 4.19Å; V193-T204 HydrophobicContact CG1-CG2 3.91Å; V193-I207 HydrophobicContact CG1-CB 3.73Å; V193-I207 HydrophobicContact CG1-CD1 4.37Å; V193-I207 HydrophobicContact CG1-CG2 3.55Å; V193-I207 HydrophobicContact CG2-CG2 4.09Å; V193-I211 HydrophobicContact CG2-CD1 3.69Å
194	A	96.2	Very high	94.9	Very high	19 Å²	19	55.2 Å²	55.2	16%	0.157	34%	0.336	C	S	.	.	H	α-helix	trans	-57.9	-41.9	177.9	0	0	0	0	0	111.8	Y190 K192 G198 S199 T204	Y190-A194 HydrophobicContact CE1-CB 4.32Å; Y190-A194 WeakPolarHBondContact O-CB 3.45Å; Y190-A194 PolarHBondContact O-N 3.33Å; K192-A194 VanDerWaalsContact C-N 3.35Å; A194-G198 WeakPolarHBondContact O-CA 3.27Å; A194-G198 PolarHBondContact O-N 3.43Å; A194-S199 PolarHBondContact O-N 2.9Å; A194-T204 HydrophobicContact CB-CG2 3.73Å
195	V	96.1	Very high	95.2	Very high	119 Å²	119	51.8 Å²	51.8	72%	0.721	32%	0.318	S	S	*	.	H	α-helix	trans	-65.9	-41.7	174.6	172.4	0	0	0	0	111.6	S191 K192 V193 G198	S191-V195 WeakPolarHBondContact O-CG2 3.3Å; S191-V195 PolarHBondContact O-N 2.84Å; K192-V195 PolarHBondContact O-N 3.42Å; V193-V195 VanDerWaalsContact C-N 3.28Å; V193-V195 PolarHBondContact O-N 3.31Å; V195-G198 PolarHBondContact O-N 3.13Å
196	A	95.4	Very high	95.3	Very high	88 Å²	88	48.2 Å²	48.2	73%	0.727	30%	0.299	S	S	*	.	H	α-helix	trans	-69.7	-37.4	-179.5	0	0	0	0	0	113.1	K192 V193	K192-A196 PolarHBondContact O-N 2.95Å; V193-A196 PolarHBondContact O-N 2.86Å
197	V	93.8	Very high	95.4	Very high	56 Å²	56	50.1 Å²	50.1	34%	0.339	31%	0.309	S	S	.	.	H	α-helix	trans	-80.1	-25.5	177.5	176.5	0	0	0	0	111.3	V193 I207	V193-V197 HydrophobicContact CG1-CG2 3.89Å; V193-V197 WeakPolarHBondContact O-CB 3.44Å; V193-V197 WeakPolarHBondContact O-CG2 3.29Å; V193-V197 PolarHBondContact O-N 2.93Å; V197-I207 HydrophobicContact CG2-CD1 3.65Å
198	G	91.9	Very high	95.7	Very high	68 Å²	68	49.7 Å²	49.7	70%	0.701	31%	0.305	S	S	*	.	T	Hydrogen-bonded Turn	trans	83.7	6.2	-178.8	0	0	0	0	0	114.6	A194 V195	A194-G198 WeakPolarHBondContact O-CA 3.27Å; A194-G198 PolarHBondContact O-N 3.43Å; V195-G198 PolarHBondContact O-N 3.13Å
199	S	90.8	Very high	95.8	Very high	68 Å²	68	42.4 Å²	42.4	48%	0.476	28%	0.277	S	S	.	.	S	Bend	trans	-152.9	151.4	176.6	54.8	0	0	0	0	112.1	A194 T204	A194-S199 PolarHBondContact O-N 2.9Å; S199-T204 PolarHBondContact O-OG1 3.41Å
200	S	91.8	Very high	95.9	Very high	90 Å²	90	44.9 Å²	44.9	63%	0.629	29%	0.289	S	S	*	.			trans	-84.9	151.8	161.8	54.7	0	0	0	0	109.8	Y190	Y190-S200 WeakPolarHBondContact OH-CB 3.38Å
201	G	94.9	Very high	95.9	Very high	16 Å²	16	48.6 Å²	48.6	17%	0.165	31%	0.309	C	S	.	.	S	Bend	trans	144.4	-177.6	-178.7	0	0	0	0	0	113.1	D67 Y190 T203 T204 L205	D67-G201 VanDerWaalsContact CG-CA 3.47Å; D67-G201 WeakPolarHBondContact OD1-CA 3.34Å; D67-G201 PolarHBondContact OD1-N 2.92Å; Y190-G201 PolarHBondContact OH-N 2.86Å; G201-T203 PolarHBondContact O-N 3.34Å; G201-T203 VanDerWaalsContact O-N 3.13Å; G201-T204 WeakPolarHBondContact O-CB 3.46Å; G201-T204 PolarHBondContact O-N 3.18Å; G201-L205 PolarHBondContact O-N 3.46Å
202	H	95.9	Very high	96	Very high	64 Å²	64	46.2 Å²	46.2	30%	0.296	29%	0.292	S	S	.	.	H	α-helix	trans	-55.1	-35.1	-173.3	66.4	79.1	0	0	0	113.7	M68 A125 W126 N128 L205 G206	M68-H202 HydrophobicContact SD-CB 4Å; A125-H202 CarbonylContact C-O 3.48Å; A125-H202 CarbonylContact O-C 3.55Å; A125-H202 WeakPolarHBondContact O-CB 3.48Å; W126-H202 PolarHBondContact O-ND1 3.11Å; N128-H202 HydrophobicContact CB-CB 4.09Å; H202-L205 PolarHBondContact O-N 2.79Å; H202-G206 PolarHBondContact O-N 3.38Å
203	T	96.3	Very high	96	Very high	46 Å²	46	40.8 Å²	40.8	28%	0.282	27%	0.269	S	S	.	.	H	α-helix	trans	-64.5	-44.8	175.1	-53.5	0	0	0	0	112.2	G201 G206 I207	G201-T203 PolarHBondContact O-N 3.34Å; G201-T203 VanDerWaalsContact O-N 3.13Å; T203-G206 PolarHBondContact O-N 2.92Å; T203-I207 HydrophobicContact CG2-CD1 3.98Å; T203-I207 WeakPolarHBondContact O-CG1 3.49Å; T203-I207 PolarHBondContact O-N 3.36Å
204	T	97.4	Very high	96.1	Very high	1 Å²	1	42.2 Å²	42.2	1%	0.006	29%	0.286	C	S	.	.	H	α-helix	trans	-66	-40.9	177.5	-69.7	0	0	0	0	110.9	Y190 V193 A194 S199 G201 S208	Y190-T204 HydrophobicContact CD1-CG2 4.28Å; Y190-T204 HydrophobicContact CD2-CG2 3.97Å; Y190-T204 HydrophobicContact CE1-CG2 3.93Å; Y190-T204 HydrophobicContact CE2-CG2 3.65Å; Y190-T204 HydrophobicContact CG-CG2 4.27Å; V193-T204 HydrophobicContact CB-CG2 4.19Å; V193-T204 HydrophobicContact CG1-CG2 3.91Å; A194-T204 HydrophobicContact CB-CG2 3.73Å; S199-T204 PolarHBondContact O-OG1 3.41Å; G201-T204 WeakPolarHBondContact O-CB 3.46Å; G201-T204 PolarHBondContact O-N 3.18Å; T204-S208 WeakPolarHBondContact O-CB 3.27Å; T204-S208 PolarHBondContact O-N 3.05Å; T204-S208 PolarHBondContact O-OG 2.94Å
205	L	97.6	Very high	96.1	Very high	0 Å²	0	42.5 Å²	42.5	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-59.7	-50.2	172.5	-179.7	62	0	0	0	111.3	L60 Q63 V64 D67 M68 A125 Y190 G201 H202 I207 S208 L209	L60-L205 HydrophobicContact CB-CD1 4.45Å; L60-L205 HydrophobicContact CD1-CD1 3.92Å; Q63-L205 HydrophobicContact CB-CD1 4.48Å; V64-L205 HydrophobicContact CB-CD2 4.49Å; V64-L205 HydrophobicContact CG2-CD1 3.98Å; V64-L205 HydrophobicContact CG2-CD2 4.1Å; D67-L205 HydrophobicContact CB-CB 4.46Å; D67-L205 HydrophobicContact CB-CD2 4.23Å; M68-L205 HydrophobicContact CG-CD2 3.84Å; M68-L205 HydrophobicContact SD-CD2 4.26Å; A125-L205 HydrophobicContact CB-CB 4.47Å; A125-L205 HydrophobicContact CB-CD2 3.97Å; A125-L205 HydrophobicContact CB-CG 3.93Å; Y190-L205 HydrophobicContact CE2-CB 4.11Å; Y190-L205 HydrophobicContact CE2-CD1 4.44Å; G201-L205 PolarHBondContact O-N 3.46Å; H202-L205 PolarHBondContact O-N 2.79Å; L205-I207 PolarHBondContact O-N 2.98Å; L205-S208 WeakPolarHBondContact O-CB 3.33Å; L205-S208 PolarHBondContact O-N 3.15Å; L205-L209 HydrophobicContact CD1-CD1 4.07Å; L205-L209 HydrophobicContact CD1-CG 4.26Å; L205-L209 HydrophobicContact CG-CD1 3.99Å; L205-L209 VanDerWaalsContact O-CG 3.32Å; L205-L209 WeakPolarHBondContact O-CG 3.45Å; L205-L209 PolarHBondContact O-N 3.19Å
206	G	97.4	Very high	96.2	Very high	0 Å²	0	36.9 Å²	36.9	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-59.5	-46.2	179.5	0	0	0	0	0	113.4	A122 H202 T203 S208 L209 M210	A122-G206 WeakPolarHBondContact O-CA 3.14Å; H202-G206 PolarHBondContact O-N 3.38Å; T203-G206 PolarHBondContact O-N 2.92Å; G206-S208 VanDerWaalsContact C-N 3.35Å; G206-S208 PolarHBondContact O-N 3.48Å; G206-L209 PolarHBondContact O-N 3.48Å; G206-M210 WeakPolarHBondContact O-CB 3.44Å; G206-M210 PolarHBondContact O-N 3.22Å
207	I	97.8	Very high	96.3	Very high	41 Å²	41	36 Å²	36	21%	0.21	24%	0.237	C	C	.	.	H	α-helix	trans	-62.6	-42.9	175.6	-67.9	163.4	0	0	0	110.7	W126 V193 V197 T203 L205 L209 M210 I211	W126-I207 HydrophobicContact CE3-CG1 3.72Å; W126-I207 HydrophobicContact CH2-CD1 4.14Å; W126-I207 HydrophobicContact CH2-CG1 3.7Å; W126-I207 HydrophobicContact CZ2-CG1 4.49Å; W126-I207 HydrophobicContact CZ3-CB 4.39Å; W126-I207 HydrophobicContact CZ3-CD1 4.2Å; W126-I207 HydrophobicContact CZ3-CG1 3.27Å; V193-I207 HydrophobicContact CG1-CB 3.73Å; V193-I207 HydrophobicContact CG1-CD1 4.37Å; V193-I207 HydrophobicContact CG1-CG2 3.55Å; V193-I207 HydrophobicContact CG2-CG2 4.09Å; V197-I207 HydrophobicContact CG2-CD1 3.65Å; T203-I207 HydrophobicContact CG2-CD1 3.98Å; T203-I207 WeakPolarHBondContact O-CG1 3.49Å; T203-I207 PolarHBondContact O-N 3.36Å; L205-I207 PolarHBondContact O-N 2.98Å; I207-L209 PolarHBondContact O-N 3.27Å; I207-M210 WeakPolarHBondContact O-CB 3.35Å; I207-M210 PolarHBondContact O-N 3.27Å; I207-M210 VanDerWaalsContact O-N 3.14Å; I207-I211 HydrophobicContact CG2-CD1 4.28Å; I207-I211 WeakPolarHBondContact O-CG1 3.25Å; I207-I211 PolarHBondContact O-N 3.23Å
208	S	97.9	Very high	96.5	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-61.2	-45.4	178.5	-57.9	0	0	0	0	111.5	M186 Y190 T204 L205 G206 M210 I211 A212	M186-S208 WeakPolarHBondContact CE-O 3.4Å; Y190-S208 WeakPolarHBondContact CA-OG 3.35Å; T204-S208 WeakPolarHBondContact O-CB 3.27Å; T204-S208 PolarHBondContact O-N 3.05Å; T204-S208 PolarHBondContact O-OG 2.94Å; L205-S208 WeakPolarHBondContact O-CB 3.33Å; L205-S208 PolarHBondContact O-N 3.15Å; G206-S208 VanDerWaalsContact C-N 3.35Å; G206-S208 PolarHBondContact O-N 3.48Å; S208-M210 VanDerWaalsContact C-N 3.3Å; S208-M210 PolarHBondContact O-N 3.29Å; S208-I211 WeakPolarHBondContact O-CB 3.49Å; S208-I211 PolarHBondContact O-N 2.94Å; S208-A212 PolarHBondContact O-N 2.85Å; S208-A212 VanDerWaalsContact O-N 3.13Å
209	L	98.1	Very high	96.7	Very high	1 Å²	1	34.5 Å²	34.5	1%	0.005	21%	0.207	C	C	.	.	H	α-helix	trans	-66.5	-30.6	175.1	-67.5	174.2	0	0	0	112.5	N56 L60 Q118 F121 A122 A125 L205 G206 I207 A212 A213	N56-L209 HydrophobicContact CB-CD2 3.77Å; L60-L209 HydrophobicContact CD1-CD2 4.11Å; Q118-L209 PolarHBondContact NE2-O 3.03Å; F121-L209 HydrophobicContact CD1-CD1 4.01Å; F121-L209 HydrophobicContact CD1-CD2 4.3Å; F121-L209 HydrophobicContact CE1-CD1 3.61Å; F121-L209 HydrophobicContact CE1-CD2 3.73Å; F121-L209 HydrophobicContact CE1-CG 4.26Å; F121-L209 HydrophobicContact CZ-CD1 4.12Å; A122-L209 HydrophobicContact CB-CB 3.63Å; A125-L209 HydrophobicContact CB-CD1 3.84Å; L205-L209 HydrophobicContact CD1-CD1 4.07Å; L205-L209 HydrophobicContact CD1-CG 4.26Å; L205-L209 HydrophobicContact CG-CD1 3.99Å; L205-L209 VanDerWaalsContact O-CG 3.32Å; L205-L209 WeakPolarHBondContact O-CG 3.45Å; L205-L209 PolarHBondContact O-N 3.19Å; G206-L209 PolarHBondContact O-N 3.48Å; I207-L209 PolarHBondContact O-N 3.27Å; L209-A212 WeakPolarHBondContact O-CB 3.49Å; L209-A212 PolarHBondContact O-N 3.31Å; L209-A213 PolarHBondContact O-N 3.12Å; L209-A213 VanDerWaalsContact O-N 3.14Å
210	M	97.9	Very high	96.9	Very high	67 Å²	67	32.7 Å²	32.7	33%	0.33	19%	0.192	S	C	.	.	H	α-helix	trans	-69.8	-36.8	174.1	-166	61.2	69.6	0	0	111.8	V119 A122 G206 I207 S208 A212 A213	V119-M210 HydrophobicContact CG1-CE 4.25Å; V119-M210 HydrophobicContact CG1-SD 4.48Å; V119-M210 HydrophobicContact CG2-SD 4.32Å; A122-M210 HydrophobicContact CB-CB 4.22Å; A122-M210 HydrophobicContact CB-CE 3.77Å; A122-M210 HydrophobicContact CB-SD 4.36Å; G206-M210 WeakPolarHBondContact O-CB 3.44Å; G206-M210 PolarHBondContact O-N 3.22Å; I207-M210 WeakPolarHBondContact O-CB 3.35Å; I207-M210 PolarHBondContact O-N 3.27Å; I207-M210 VanDerWaalsContact O-N 3.14Å; S208-M210 VanDerWaalsContact C-N 3.3Å; S208-M210 PolarHBondContact O-N 3.29Å; M210-A212 VanDerWaalsContact C-N 3.29Å; M210-A212 PolarHBondContact O-N 3.22Å; M210-A213 WeakPolarHBondContact O-CB 3.23Å; M210-A213 PolarHBondContact O-N 3.05Å; M210-A213 VanDerWaalsContact O-N 3.12Å; M210-A213 HydrophobicContact SD-CB 4.35Å
211	I	97.9	Very high	97.2	Very high	94 Å²	94	32.6 Å²	32.6	48%	0.482	18%	0.184	S	C	.	.	H	α-helix	trans	-61.7	-41.5	171.3	-66.7	167.2	0	0	0	110	V189 V193 I207 S208 A213 G214	V189-I211 HydrophobicContact CG1-CB 4.34Å; V189-I211 HydrophobicContact CG1-CD1 3.96Å; V189-I211 HydrophobicContact CG1-CG2 4.23Å; V193-I211 HydrophobicContact CG2-CD1 3.69Å; I207-I211 HydrophobicContact CG2-CD1 4.28Å; I207-I211 WeakPolarHBondContact O-CG1 3.25Å; I207-I211 PolarHBondContact O-N 3.23Å; S208-I211 WeakPolarHBondContact O-CB 3.49Å; S208-I211 PolarHBondContact O-N 2.94Å; I211-A213 PolarHBondContact O-N 3.22Å; I211-G214 PolarHBondContact O-N 2.82Å
212	A	97.5	Very high	97.3	Very high	2 Å²	2	31.8 Å²	31.8	2%	0.017	18%	0.176	C	C	.	.	H	α-helix	trans	-59.5	-32.4	174.6	0	0	0	0	0	112.6	F52 C53 M186 S208 L209 M210 G214 T215	F52-A212 HydrophobicContact CD1-CB 4.39Å; F52-A212 HydrophobicContact CE1-CB 3.84Å; C53-A212 PolarHBondContact SG-O 3.28Å; C53-A212 VanDerWaalsContact SG-O 3.41Å; M186-A212 HydrophobicContact CE-CB 3.94Å; M186-A212 HydrophobicContact SD-CB 3.95Å; S208-A212 PolarHBondContact O-N 2.85Å; S208-A212 VanDerWaalsContact O-N 3.13Å; L209-A212 WeakPolarHBondContact O-CB 3.49Å; L209-A212 PolarHBondContact O-N 3.31Å; M210-A212 VanDerWaalsContact C-N 3.29Å; M210-A212 PolarHBondContact O-N 3.22Å; A212-G214 PolarHBondContact O-N 3.34Å; A212-G214 VanDerWaalsContact O-N 3.12Å; A212-T215 WeakPolarHBondContact O-CB 3.43Å; A212-T215 PolarHBondContact O-N 3.22Å; A212-T215 PolarHBondContact O-OG1 3.03Å
213	A	97.4	Very high	97.3	Very high	4 Å²	4	28.8 Å²	28.8	3%	0.033	16%	0.162	C	C	.	.	H	α-helix	trans	-59.3	-23	175	0	0	0	0	0	113.2	Q118 V119 L209 M210 I211 T215 C216 V217	Q118-A213 HydrophobicContact CG-CB 3.74Å; V119-A213 HydrophobicContact CG2-CB 4.19Å; L209-A213 PolarHBondContact O-N 3.12Å; L209-A213 VanDerWaalsContact O-N 3.14Å; M210-A213 WeakPolarHBondContact O-CB 3.23Å; M210-A213 PolarHBondContact O-N 3.05Å; M210-A213 VanDerWaalsContact O-N 3.12Å; M210-A213 HydrophobicContact SD-CB 4.35Å; I211-A213 PolarHBondContact O-N 3.22Å; A213-T215 PolarHBondContact O-N 3.43Å; A213-C216 WeakPolarHBondContact O-CB 3.49Å; A213-C216 PolarHBondContact O-N 3.18Å; A213-V217 PolarHBondContact O-N 3.05Å
214	G	97.6	Very high	97.3	Very high	42 Å²	42	31 Å²	31	43%	0.433	17%	0.171	S	C	.	.	H	α-helix	trans	-56.8	-31.5	171.1	0	0	0	0	0	113.2	I211 A212 V217 F218	I211-G214 PolarHBondContact O-N 2.82Å; A212-G214 PolarHBondContact O-N 3.34Å; A212-G214 VanDerWaalsContact O-N 3.12Å; G214-V217 PolarHBondContact O-N 3.47Å; G214-F218 WeakPolarHBondContact O-CB 3.5Å; G214-F218 PolarHBondContact O-N 2.66Å
215	T	97.1	Very high	97.2	Very high	25 Å²	25	33 Å²	33	15%	0.153	18%	0.184	C	C	.	.	H	α-helix	trans	-69.9	-36.9	174.6	67.8	0	0	0	0	112.1	F48 F52 C53 A212 A213 F218 S219	F48-T215 HydrophobicContact CE1-CG2 4.32Å; F52-T215 HydrophobicContact CD1-CG2 4.05Å; F52-T215 HydrophobicContact CD2-CG2 4.14Å; F52-T215 HydrophobicContact CE1-CG2 4.25Å; F52-T215 HydrophobicContact CE2-CG2 4.3Å; F52-T215 HydrophobicContact CG-CG2 4.02Å; F52-T215 HydrophobicContact CZ-CG2 4.37Å; C53-T215 PolarHBondContact SG-OG1 3.29Å; A212-T215 WeakPolarHBondContact O-CB 3.43Å; A212-T215 PolarHBondContact O-N 3.22Å; A212-T215 PolarHBondContact O-OG1 3.03Å; A213-T215 PolarHBondContact O-N 3.43Å; T215-F218 PolarHBondContact O-N 2.64Å; T215-S219 PolarHBondContact O-N 3.48Å; T215-S219 PolarHBondContact O-OG 3.09Å
216	C	97.2	Very high	96.9	Very high	2 Å²	2	33.1 Å²	33.1	1%	0.014	18%	0.184	C	C	.	.	H	α-helix	trans	-68.1	-40.4	173.3	-61.5	0	0	0	0	111.8	C53 C115 A213 F218 S219 L220	C53-C216 PolarHBondContact SG-SG 2.65Å; C115-C216 HydrophobicContact CB-CB 4.03Å; A213-C216 WeakPolarHBondContact O-CB 3.49Å; A213-C216 PolarHBondContact O-N 3.18Å; C216-F218 VanDerWaalsContact C-N 3.32Å; C216-F218 PolarHBondContact O-N 3Å; C216-S219 PolarHBondContact O-N 3.42Å; C216-L220 WeakPolarHBondContact O-CB 3.32Å; C216-L220 PolarHBondContact O-N 3.41Å
217	V	97.9	Very high	96.7	Very high	68 Å²	68	33.5 Å²	33.5	41%	0.412	19%	0.188	S	C	.	.	H	α-helix	trans	-61.4	-42.8	174.2	174	0	0	0	0	110.5	A213 G214 L220 I221	A213-V217 PolarHBondContact O-N 3.05Å; G214-V217 PolarHBondContact O-N 3.47Å; V217-L220 WeakPolarHBondContact O-CB 3.48Å; V217-L220 PolarHBondContact O-N 3.24Å; V217-I221 HydrophobicContact CG1-CD1 4.14Å; V217-I221 WeakPolarHBondContact O-CG1 3.3Å; V217-I221 PolarHBondContact O-N 3.28Å
218	F	97.2	Very high	96.4	Very high	91 Å²	91	37.9 Å²	37.9	40%	0.399	21%	0.206	S	C	.	.	H	α-helix	trans	-58.9	-47.8	174	173.9	-107	0	0	0	111.9	F45 G214 T215 C216 L220 I221 C222	F45-F218 HydrophobicContact CB-CE1 3.78Å; F45-F218 HydrophobicContact CB-CZ 4.22Å; F45-F218 AromaticContact CD1-CE1 3.67Å; F45-F218 HydrophobicContact CD1-CE1 3.67Å; F45-F218 HydrophobicContact CD1-CZ 4.26Å; F45-F218 HydrophobicContact CE1-CE1 4.43Å; F45-F218 AromaticContact CG-CE1 3.8Å; F45-F218 HydrophobicContact CG-CE1 3.8Å; F45-F218 HydrophobicContact CG-CZ 4.1Å; G214-F218 WeakPolarHBondContact O-CB 3.5Å; G214-F218 PolarHBondContact O-N 2.66Å; T215-F218 PolarHBondContact O-N 2.64Å; C216-F218 VanDerWaalsContact C-N 3.32Å; C216-F218 PolarHBondContact O-N 3Å; F218-L220 VanDerWaalsContact C-N 3.3Å; F218-L220 PolarHBondContact O-N 3.48Å; F218-I221 WeakPolarHBondContact O-CB 3.35Å; F218-I221 PolarHBondContact O-N 3.11Å; F218-I221 VanDerWaalsContact O-N 3.14Å; F218-C222 PolarHBondContact O-N 3.13Å; F218-C222 PolarHBondContact O-SG 3.15Å
219	S	96.1	Very high	96.1	Very high	2 Å²	2	38.8 Å²	38.8	1%	0.014	21%	0.211	C	C	.	.	H	α-helix	trans	-61	-35.6	174.7	-73.5	0	0	0	0	113.2	F45 L46 G49 T215 C216 C222 A223	F45-S219 PolarHBondContact O-OG 3.1Å; L46-S219 VanDerWaalsContact O-CB 3.26Å; L46-S219 WeakPolarHBondContact O-CB 3.37Å; L46-S219 PolarHBondContact O-OG 2.66Å; G49-S219 PolarHBondContact N-OG 3.45Å; T215-S219 PolarHBondContact O-N 3.48Å; T215-S219 PolarHBondContact O-OG 3.09Å; C216-S219 PolarHBondContact O-N 3.42Å; S219-C222 WeakPolarHBondContact O-CB 3.29Å; S219-C222 PolarHBondContact O-N 2.8Å; S219-A223 PolarHBondContact O-N 3.34Å
220	L	96.8	Very high	95.7	Very high	30 Å²	30	39 Å²	39	16%	0.157	21%	0.212	C	C	.	.	H	α-helix	trans	-66.3	-39.6	173.8	-179.8	62.5	0	0	0	111.9	I108 S111 L112 C216 V217 F218 C222 A223 L224	I108-L220 HydrophobicContact CG2-CD1 4.46Å; S111-L220 VanDerWaalsContact OG-CA 3.25Å; S111-L220 WeakPolarHBondContact OG-CA 3.11Å; S111-L220 PolarHBondContact OG-N 3.18Å; L112-L220 HydrophobicContact CD1-CD2 4.27Å; C216-L220 WeakPolarHBondContact O-CB 3.32Å; C216-L220 PolarHBondContact O-N 3.41Å; V217-L220 WeakPolarHBondContact O-CB 3.48Å; V217-L220 PolarHBondContact O-N 3.24Å; F218-L220 VanDerWaalsContact C-N 3.3Å; F218-L220 PolarHBondContact O-N 3.48Å; L220-C222 VanDerWaalsContact C-N 3.32Å; L220-C222 PolarHBondContact O-N 3.38Å; L220-A223 WeakPolarHBondContact O-CB 3.47Å; L220-A223 PolarHBondContact O-N 3.45Å; L220-L224 WeakPolarHBondContact O-CG 3.06Å; L220-L224 PolarHBondContact O-N 3.12Å
221	I	97.6	Very high	95.2	Very high	88 Å²	88	41.6 Å²	41.6	45%	0.451	22%	0.222	S	C	.	.	H	α-helix	trans	-61.2	-43.7	171.9	-66.9	164.5	0	0	0	109.8	V217 F218 A223 L224 V225	V217-I221 HydrophobicContact CG1-CD1 4.14Å; V217-I221 WeakPolarHBondContact O-CG1 3.3Å; V217-I221 PolarHBondContact O-N 3.28Å; F218-I221 WeakPolarHBondContact O-CB 3.35Å; F218-I221 PolarHBondContact O-N 3.11Å; F218-I221 VanDerWaalsContact O-N 3.14Å; I221-A223 VanDerWaalsContact C-N 3.32Å; I221-A223 PolarHBondContact O-N 3.07Å; I221-L224 PolarHBondContact O-N 3.48Å; I221-V225 HydrophobicContact CG2-CG2 4.35Å; I221-V225 VanDerWaalsContact O-CG2 3.31Å; I221-V225 WeakPolarHBondContact O-CG2 3.21Å; I221-V225 PolarHBondContact O-N 3.04Å
222	C	96.1	Very high	94.8	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-58.9	-42	174.1	-61	0	0	0	0	111.9	F42 F218 S219 L220 V225 L226	F42-C222 HydrophobicContact CD1-CB 4.04Å; F218-C222 PolarHBondContact O-N 3.13Å; F218-C222 PolarHBondContact O-SG 3.15Å; S219-C222 WeakPolarHBondContact O-CB 3.29Å; S219-C222 PolarHBondContact O-N 2.8Å; L220-C222 VanDerWaalsContact C-N 3.32Å; L220-C222 PolarHBondContact O-N 3.38Å; C222-V225 PolarHBondContact O-N 3.41Å; C222-L226 WeakPolarHBondContact O-CB 3.36Å; C222-L226 VanDerWaalsContact O-CG 3.32Å; C222-L226 WeakPolarHBondContact O-CG 3.22Å; C222-L226 PolarHBondContact O-N 3.37Å
223	A	95.6	Very high	94.2	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-60.3	-45.2	175.6	0	0	0	0	0	112.3	L46 T107 I108 S219 L220 I221 L226 G227	L46-A223 HydrophobicContact CD1-CB 3.53Å; T107-A223 HydrophobicContact CG2-CB 4.09Å; I108-A223 HydrophobicContact CG1-CB 4.41Å; S219-A223 PolarHBondContact O-N 3.34Å; L220-A223 WeakPolarHBondContact O-CB 3.47Å; L220-A223 PolarHBondContact O-N 3.45Å; I221-A223 VanDerWaalsContact C-N 3.32Å; I221-A223 PolarHBondContact O-N 3.07Å; A223-L226 PolarHBondContact O-N 3.34Å; A223-G227 PolarHBondContact O-N 2.91Å
224	L	96.4	Very high	93.5	Very high	92 Å²	92	43.1 Å²	43.1	48%	0.482	22%	0.224	S	C	.	.	H	α-helix	trans	-63.8	-43.9	177.6	-69.4	170.6	0	0	0	111.6	I108 L220 I221 G227 F228	I108-L224 HydrophobicContact CD1-CD2 3.92Å; I108-L224 HydrophobicContact CG1-CD2 4.11Å; I108-L224 HydrophobicContact CG2-CD2 4.09Å; L220-L224 WeakPolarHBondContact O-CG 3.06Å; L220-L224 PolarHBondContact O-N 3.12Å; I221-L224 PolarHBondContact O-N 3.48Å; L224-G227 PolarHBondContact O-N 3.28Å; L224-F228 PolarHBondContact O-N 3.08Å
225	V	95.3	Very high	92.9	Very high	44 Å²	44	50 Å²	50	27%	0.267	24%	0.237	S	C	.	.	H	α-helix	trans	-63.4	-46.9	176.7	173.6	0	0	0	0	110.5	F42 I221 C222 G227 F228 L229	F42-V225 HydrophobicContact CD1-CB 4.28Å; F42-V225 HydrophobicContact CD1-CG1 4.12Å; F42-V225 HydrophobicContact CD2-CG1 3.91Å; F42-V225 HydrophobicContact CE1-CB 4.23Å; F42-V225 HydrophobicContact CE1-CG1 3.95Å; F42-V225 HydrophobicContact CE1-CG2 4.37Å; F42-V225 HydrophobicContact CE2-CG1 3.74Å; F42-V225 HydrophobicContact CG-CG1 4.12Å; F42-V225 HydrophobicContact CZ-CG1 3.76Å; I221-V225 HydrophobicContact CG2-CG2 4.35Å; I221-V225 VanDerWaalsContact O-CG2 3.31Å; I221-V225 WeakPolarHBondContact O-CG2 3.21Å; I221-V225 PolarHBondContact O-N 3.04Å; C222-V225 PolarHBondContact O-N 3.41Å; V225-G227 PolarHBondContact O-N 3.3Å; V225-F228 WeakPolarHBondContact O-CB 3.43Å; V225-F228 PolarHBondContact O-N 2.85Å; V225-F228 VanDerWaalsContact O-N 3.15Å; V225-L229 HydrophobicContact CG1-CD1 3.93Å; V225-L229 HydrophobicContact CG1-CG 4.15Å; V225-L229 VanDerWaalsContact O-CG 3.31Å; V225-L229 WeakPolarHBondContact O-CG 3.43Å; V225-L229 PolarHBondContact O-N 2.78Å
226	L	93.1	Very high	92.2	Very high	2 Å²	2	51.5 Å²	51.5	1%	0.01	24%	0.243	C	C	.	.	H	α-helix	trans	-59	-45.1	175.6	-77.1	169.7	0	0	0	112.1	V39 F42 M43 L46 C222 A223 F228 L229 D230	V39-L226 HydrophobicContact CG1-CD2 3.87Å; F42-L226 HydrophobicContact CB-CD1 4.19Å; F42-L226 HydrophobicContact CB-CD2 3.71Å; F42-L226 HydrophobicContact CB-CG 3.7Å; M43-L226 HydrophobicContact CB-CD1 4.43Å; M43-L226 HydrophobicContact CB-CD2 4.46Å; L46-L226 HydrophobicContact CB-CD1 4.27Å; L46-L226 HydrophobicContact CD1-CD1 4.37Å; L46-L226 HydrophobicContact CD2-CD1 4.11Å; L46-L226 HydrophobicContact CG-CD1 4.5Å; C222-L226 WeakPolarHBondContact O-CB 3.36Å; C222-L226 VanDerWaalsContact O-CG 3.32Å; C222-L226 WeakPolarHBondContact O-CG 3.22Å; C222-L226 PolarHBondContact O-N 3.37Å; A223-L226 PolarHBondContact O-N 3.34Å; L226-F228 VanDerWaalsContact C-N 3.26Å; L226-F228 PolarHBondContact O-N 3.42Å; L226-L229 PolarHBondContact O-N 3Å; L226-D230 VanDerWaalsContact O-CB 3.24Å; L226-D230 WeakPolarHBondContact O-CB 3.43Å; L226-D230 PolarHBondContact O-N 3.33Å
227	G	92.1	Very high	91.3	Very high	8 Å²	8	54.5 Å²	54.5	8%	0.082	26%	0.259	C	S	.	.	H	α-helix	trans	-58.5	-39.4	175.9	0	0	0	0	0	112.3	A223 L224 V225 K231	A223-G227 PolarHBondContact O-N 2.91Å; L224-G227 PolarHBondContact O-N 3.28Å; V225-G227 PolarHBondContact O-N 3.3Å; G227-K231 WeakPolarHBondContact O-CB 3.35Å; G227-K231 PolarHBondContact O-N 2.74Å
228	F	92.6	Very high	90.2	Very high	134 Å²	134	59.3 Å²	59.3	59%	0.588	28%	0.277	S	S	*	.	H	α-helix	trans	-68.2	-48.4	174.8	174.4	-98	0	0	0	112.7	L224 V225 L226 D230 K231 R232	L224-F228 PolarHBondContact O-N 3.08Å; V225-F228 WeakPolarHBondContact O-CB 3.43Å; V225-F228 PolarHBondContact O-N 2.85Å; V225-F228 VanDerWaalsContact O-N 3.15Å; L226-F228 VanDerWaalsContact C-N 3.26Å; L226-F228 PolarHBondContact O-N 3.42Å; F228-D230 VanDerWaalsContact C-N 3.31Å; F228-D230 PolarHBondContact O-N 2.93Å; F228-K231 PolarHBondContact O-N 2.98Å; F228-R232 WeakPolarHBondContact O-CB 3.44Å; F228-R232 PolarHBondContact O-N 3.32Å
229	L	90.9	Very high	88.9	Confident	18 Å²	18	59.2 Å²	59.2	9%	0.094	28%	0.276	C	S	.	.	H	α-helix	trans	-61.1	-41.8	179.4	-66.2	179.9	0	0	0	111.1	V38 V39 F42 V225 L226 R232 A233	V38-L229 HydrophobicContact CG1-CD1 4.4Å; V39-L229 HydrophobicContact CG2-CB 4.31Å; V39-L229 HydrophobicContact CG2-CD1 3.88Å; F42-L229 HydrophobicContact CD2-CD1 4.26Å; V225-L229 HydrophobicContact CG1-CD1 3.93Å; V225-L229 HydrophobicContact CG1-CG 4.15Å; V225-L229 VanDerWaalsContact O-CG 3.31Å; V225-L229 WeakPolarHBondContact O-CG 3.43Å; V225-L229 PolarHBondContact O-N 2.78Å; L226-L229 PolarHBondContact O-N 3Å; L229-R232 PolarHBondContact O-N 2.94Å; L229-A233 WeakPolarHBondContact O-CB 3.3Å; L229-A233 PolarHBondContact O-N 3.5Å
230	D	88.8	Confident	87.2	Confident	7 Å²	7	67.5 Å²	67.5	4%	0.037	31%	0.314	C	S	.	.	H	α-helix	trans	-66.6	-43	177.4	-167.4	84.4	0	0	0	112.6	R104 Y154 W158 L226 F228 R232 A233 E234	R104-D230 HydrophobicContact CG-CB 4.47Å; R104-D230 IonicContact CZ-OD2 3.68Å; R104-D230 IonicContact NE-OD2 3.96Å; R104-D230 PolarHBondContact NE-OD2 3.36Å; R104-D230 PolarHBondContact NH2-O 3.46Å; R104-D230 VanDerWaalsContact NH2-O 3.15Å; R104-D230 IonicContact NH2-OD2 3.06Å; R104-D230 PolarHBondContact NH2-OD2 2.96Å; Y154-D230 HydrophobicContact CE1-CB 3.96Å; W158-D230 HydrophobicContact CZ2-CB 4.19Å; W158-D230 PolarHBondContact NE1-OD1 3.19Å; L226-D230 VanDerWaalsContact O-CB 3.24Å; L226-D230 WeakPolarHBondContact O-CB 3.43Å; L226-D230 PolarHBondContact O-N 3.33Å; F228-D230 VanDerWaalsContact C-N 3.31Å; F228-D230 PolarHBondContact O-N 2.93Å; D230-R232 VanDerWaalsContact C-N 3.29Å; D230-R232 PolarHBondContact O-N 3.25Å; D230-A233 PolarHBondContact O-N 3.04Å; D230-E234 PolarHBondContact O-N 2.98Å
231	K	88.6	Confident	85.4	Confident	121 Å²	121	70 Å²	70	53%	0.526	33%	0.325	S	S	.	.	H	α-helix	trans	-61.9	-38.3	173.5	-175.4	175.3	-177.5	175.3	0	112.4	G227 F228 R235	G227-K231 WeakPolarHBondContact O-CB 3.35Å; G227-K231 PolarHBondContact O-N 2.74Å; F228-K231 PolarHBondContact O-N 2.98Å; K231-R235 PolarHBondContact O-N 3.16Å
232	R	88.4	Confident	83.3	Confident	62 Å²	62	68.5 Å²	68.5	23%	0.234	33%	0.332	C	S	.	.	H	α-helix	trans	-68.2	-43.8	176.5	-177.9	-179.2	174.7	-146.7	-4.1	111.1	C28 F228 L229 D230 R235 I236	C28-R232 PolarHBondContact O-NH2 3.36Å; F228-R232 WeakPolarHBondContact O-CB 3.44Å; F228-R232 PolarHBondContact O-N 3.32Å; L229-R232 PolarHBondContact O-N 2.94Å; D230-R232 VanDerWaalsContact C-N 3.29Å; D230-R232 PolarHBondContact O-N 3.25Å; R232-R235 PolarHBondContact O-N 2.87Å; R232-I236 HydrophobicContact CG-CD1 3.7Å; R232-I236 HydrophobicContact CG-CG1 4.5Å; R232-I236 VanDerWaalsContact O-CG1 3.3Å; R232-I236 WeakPolarHBondContact O-CG1 3.29Å; R232-I236 PolarHBondContact O-N 3.32Å; R232-I236 VanDerWaalsContact O-N 3.07Å
233	A	84.8	Confident	81.2	Confident	7 Å²	7	76.9 Å²	76.9	6%	0.058	36%	0.364	C	S	.	.	H	α-helix	trans	-62	-45.3	178	0	0	0	0	0	111.8	P30 W158 L229 D230 R235 I236 L237	P30-A233 HydrophobicContact CB-CB 3.78Å; P30-A233 HydrophobicContact CG-CB 4.09Å; W158-A233 HydrophobicContact CH2-CB 3.6Å; W158-A233 HydrophobicContact CZ2-CB 3.94Å; W158-A233 HydrophobicContact CZ3-CB 4.48Å; L229-A233 WeakPolarHBondContact O-CB 3.3Å; L229-A233 PolarHBondContact O-N 3.5Å; D230-A233 PolarHBondContact O-N 3.04Å; A233-R235 VanDerWaalsContact C-N 3.33Å; A233-R235 PolarHBondContact O-N 3.39Å; A233-I236 PolarHBondContact O-N 2.94Å; A233-L237 VanDerWaalsContact O-CB 3.3Å; A233-L237 WeakPolarHBondContact O-CB 3.35Å; A233-L237 PolarHBondContact O-N 2.78Å
234	E	84.4	Confident	79.2	Confident	62 Å²	62	80.3 Å²	80.3	29%	0.29	38%	0.384	S	S	.	.	H	α-helix	trans	-57.3	-45.8	174.6	174.5	177.2	-143.2	0	0	111.8	R104 D230 I236 H238 K239	R104-E234 IonicContact CZ-OE2 2.69Å; R104-E234 IonicContact NH1-OE2 3.56Å; R104-E234 PolarHBondContact NH1-OE2 3.3Å; R104-E234 IonicContact NH2-OE2 2.85Å; R104-E234 PolarHBondContact NH2-OE2 3.07Å; D230-E234 PolarHBondContact O-N 2.98Å; E234-I236 VanDerWaalsContact C-N 3.33Å; E234-I236 PolarHBondContact O-N 3.12Å; E234-H238 VanDerWaalsContact O-CA 3.32Å; E234-H238 WeakPolarHBondContact O-CA 3.32Å; E234-H238 PolarHBondContact O-N 3.37Å; E234-K239 WeakPolarHBondContact CG-O 3.32Å
235	R	85.1	Confident	76.9	Confident	186 Å²	186	78.6 Å²	78.6	70%	0.702	39%	0.389	S	S	*	.	H	α-helix	trans	-63.5	-37.9	179.8	-175.6	-175.5	-71.7	177.9	-6.4	112.7	K231 R232 A233	K231-R235 PolarHBondContact O-N 3.16Å; R232-R235 PolarHBondContact O-N 2.87Å; A233-R235 VanDerWaalsContact C-N 3.33Å; A233-R235 PolarHBondContact O-N 3.39Å
236	I	81.4	Confident	75.1	Confident	57 Å²	57	79.8 Å²	79.8	29%	0.292	39%	0.392	S	S	.	.	H	α-helix	trans	-82	-39	-175.7	-66.6	170.6	0	0	0	111.4	L24 P30 R232 A233 E234	L24-I236 HydrophobicContact CD1-CD1 4.12Å; L24-I236 HydrophobicContact CD1-CG2 4.47Å; P30-I236 HydrophobicContact CG-CB 4.25Å; P30-I236 HydrophobicContact CG-CD1 3.97Å; P30-I236 HydrophobicContact CG-CG2 4.28Å; R232-I236 HydrophobicContact CG-CD1 3.7Å; R232-I236 HydrophobicContact CG-CG1 4.5Å; R232-I236 VanDerWaalsContact O-CG1 3.3Å; R232-I236 WeakPolarHBondContact O-CG1 3.29Å; R232-I236 PolarHBondContact O-N 3.32Å; R232-I236 VanDerWaalsContact O-N 3.07Å; A233-I236 PolarHBondContact O-N 2.94Å; E234-I236 VanDerWaalsContact C-N 3.33Å; E234-I236 PolarHBondContact O-N 3.12Å
237	L	78.6	Confident	73.6	Confident	65 Å²	65	82.9 Å²	82.9	34%	0.34	41%	0.411	S	S	.	.	H	α-helix	trans	-95	-2.8	-175	-63.5	176.3	0	0	0	113.4	P30 A233 K239	P30-L237 HydrophobicContact CB-CD1 3.73Å; P30-L237 HydrophobicContact CB-CG 4.09Å; A233-L237 VanDerWaalsContact O-CB 3.3Å; A233-L237 WeakPolarHBondContact O-CB 3.35Å; A233-L237 PolarHBondContact O-N 2.78Å; L237-K239 HydrophobicContact CB-CB 4.3Å; L237-K239 PolarHBondContact O-N 2.71Å; L237-K239 VanDerWaalsContact O-N 3.08Å
238	H	75.1	Confident	72.3	Confident	170 Å²	170	84.5 Å²	84.5	79%	0.787	42%	0.417	S	S	*	.	T	Hydrogen-bonded Turn	trans	48.7	34.8	-173.4	-64.5	-74.2	0	0	0	113.2	E234	E234-H238 VanDerWaalsContact O-CA 3.32Å; E234-H238 WeakPolarHBondContact O-CA 3.32Å; E234-H238 PolarHBondContact O-N 3.37Å
239	K	68.6	Low	71.3	Confident	89 Å²	89	83.8 Å²	83.8	39%	0.387	41%	0.414	S	S	.	.			trans	-80.8	123.4	-173.7	-166.9	-176.5	-177.1	-165.8	0	109.7	N157 E234 L237 Q241	N157-K239 PolarHBondContact O-NZ 3.38Å; N157-K239 PolarHBondContact OD1-NZ 2.86Å; E234-K239 WeakPolarHBondContact CG-O 3.32Å; L237-K239 HydrophobicContact CB-CB 4.3Å; L237-K239 PolarHBondContact O-N 2.71Å; L237-K239 VanDerWaalsContact O-N 3.08Å; K239-Q241 PolarHBondContact O-N 2.97Å
240	E	61.7	Low	70.4	Confident	175 Å²	175	88.5 Å²	88.5	82%	0.818	44%	0.439	S	S	*	.			trans	-61.9	137.1	170.4	-68.6	-165.7	154.4	0	0	110.3	G242	E240-G242 PolarHBondContact O-N 3.45Å
241	Q	57.8	Low	69.9	Low	83 Å²	83	92.3 Å²	92.3	39%	0.388	46%	0.462	S	S	.	.			trans	-59.4	115.5	170.2	-83.1	179.6	3.8	0	0	108.6	K239 R243	K239-Q241 PolarHBondContact O-N 2.97Å; Q241-R243 VanDerWaalsContact C-N 3.31Å; Q241-R243 PolarHBondContact O-N 2.92Å
242	G	53.3	Low	69.3	Low	57 Å²	57	87.2 Å²	87.2	59%	0.588	44%	0.44	S	S	*	.			trans	-61.6	93.9	174.6	0	0	0	0	0	109.8	E240 T244	E240-G242 PolarHBondContact O-N 3.45Å; G242-T244 PolarHBondContact O-N 3.26Å
243	R	53	Low	68.9	Low	176 Å²	176	85.4 Å²	85.4	66%	0.664	44%	0.436	S	S	*	.			trans	-77	115	165.7	-75.8	177.2	144.8	153.7	-3	107.2	Q241 G245	Q241-R243 VanDerWaalsContact C-N 3.31Å; Q241-R243 PolarHBondContact O-N 2.92Å; R243-G245 PolarHBondContact O-N 3.41Å; R243-G245 VanDerWaalsContact O-N 3.08Å
244	T	53.8	Low	68.7	Low	71 Å²	71	93.8 Å²	93.8	44%	0.436	47%	0.471	S	S	.	.			trans	-60	109.9	158.2	28.1	0	0	0	0	106.4	D98 G242 E246	D98-T244 PolarHBondContact OD1-OG1 3.2Å; D98-T244 PolarHBondContact OD2-OG1 3.2Å; G242-T244 PolarHBondContact O-N 3.26Å; T244-E246 PolarHBondContact O-N 3Å; T244-E246 VanDerWaalsContact O-N 3.16Å
245	G	48.8	Very low	68.7	Low	57 Å²	57	96.3 Å²	96.3	59%	0.588	49%	0.487	S	S	*	.			trans	-68.1	-8.6	-174	0	0	0	0	0	114	R99 R243 V247	R99-G245 PolarHBondContact NH2-O 3.31Å; R99-G245 VanDerWaalsContact NH2-O 3.12Å; R243-G245 PolarHBondContact O-N 3.41Å; R243-G245 VanDerWaalsContact O-N 3.08Å; G245-V247 PolarHBondContact O-N 3.42Å
246	E	56.6	Low	69	Low	68 Å²	68	88.2 Å²	88.2	32%	0.318	46%	0.457	S	S	.	.			trans	-64.2	129.3	-177.7	-90.9	170.5	-140.2	0	0	112.4	T244 E377 G381	T244-E246 PolarHBondContact O-N 3Å; T244-E246 VanDerWaalsContact O-N 3.16Å; E246-E377 VanDerWaalsContact CD-O 3.26Å; E246-G381 PolarHBondContact OE2-N 3.26Å
247	V	60.6	Low	69.5	Low	68 Å²	68	87.1 Å²	87.1	41%	0.412	45%	0.454	S	S	.	.			trans	-104.5	117.3	170.2	-179.9	0	0	0	0	106	G245 K249	G245-V247 PolarHBondContact O-N 3.42Å; V247-K249 PolarHBondContact O-N 2.69Å; V247-K249 VanDerWaalsContact O-N 3.15Å
248	I	66.4	Low	70.2	Confident	41 Å²	41	88.5 Å²	88.5	21%	0.21	46%	0.461	C	S	.	.			trans	-61.6	117.5	175.5	-62.6	171.5	0	0	0	108	F91 F95 T382	F91-I248 WeakPolarHBondContact O-CD1 3.48Å; F95-I248 HydrophobicContact CB-CD1 4.39Å; I248-T382 HydrophobicContact CG2-CG2 4.29Å
249	K	71.3	Confident	71.1	Confident	119 Å²	119	80.4 Å²	80.4	52%	0.517	42%	0.424	S	S	.	.			trans	-112.2	111	175.1	-66.5	175	-172.2	173.3	0	108.4	V247 T251 D252 T382	V247-K249 PolarHBondContact O-N 2.69Å; V247-K249 VanDerWaalsContact O-N 3.15Å; K249-T251 PolarHBondContact O-N 2.85Å; K249-D252 WeakPolarHBondContact CB-OD1 3.4Å; K249-D252 WeakPolarHBondContact O-CB 3.16Å; K249-D252 PolarHBondContact O-N 3.28Å; K249-T382 PolarHBondContact N-OG1 2.92Å; K249-T382 WeakPolarHBondContact O-CG2 3.31Å
250	L	72.5	Confident	72.3	Confident	118 Å²	118	76.2 Å²	76.2	62%	0.618	41%	0.406	S	S	*	.	G	3₁₀ helix	trans	-58.1	-19.8	176.9	-72.4	162.4	0	0	0	113.2	F91 D252 V253	F91-L250 HydrophobicContact CD1-CD2 3.88Å; F91-L250 HydrophobicContact CE1-CD2 4.14Å; F91-L250 HydrophobicContact CG-CD2 4.19Å; L250-D252 VanDerWaalsContact C-N 3.28Å; L250-D252 PolarHBondContact O-N 2.64Å; L250-V253 WeakPolarHBondContact O-CG2 3.05Å
251	T	76.9	Confident	74	Confident	86 Å²	86	72.2 Å²	72.2	53%	0.528	38%	0.383	S	S	.	.	G	3₁₀ helix	trans	-66.9	-27.4	174.2	48.7	0	0	0	0	113.4	K249 V253 K254	K249-T251 PolarHBondContact O-N 2.85Å; T251-V253 PolarHBondContact O-N 2.75Å; T251-V253 VanDerWaalsContact O-N 3.14Å; T251-K254 WeakPolarHBondContact O-CB 3.12Å; T251-K254 PolarHBondContact O-N 3.37Å; T251-K254 VanDerWaalsContact O-N 3.1Å
252	D	77.3	Confident	75.8	Confident	14 Å²	14	69.3 Å²	69.3	8%	0.075	37%	0.37	C	S	.	.	G	3₁₀ helix	trans	-62.8	-23.4	-177.4	-55.7	-16.5	0	0	0	111.7	K249 L250 K254 D255 F256 Q379 T382	K249-D252 WeakPolarHBondContact CB-OD1 3.4Å; K249-D252 WeakPolarHBondContact O-CB 3.16Å; K249-D252 PolarHBondContact O-N 3.28Å; L250-D252 VanDerWaalsContact C-N 3.28Å; L250-D252 PolarHBondContact O-N 2.64Å; D252-K254 PolarHBondContact O-N 3.44Å; D252-K254 VanDerWaalsContact O-N 3.09Å; D252-D255 PolarHBondContact O-N 3.3Å; D252-F256 HydrophobicContact CB-CE1 4.46Å; D252-F256 VanDerWaalsContact O-CD1 3.25Å; D252-F256 WeakPolarHBondContact O-CD1 3.42Å; D252-F256 WeakPolarHBondContact O-CE1 3.48Å; D252-Q379 HydrophobicContact CB-CG 4.08Å; D252-T382 HydrophobicContact CB-CG2 4.17Å; D252-T382 PolarHBondContact OD2-OG1 3.49Å
253	V	78.3	Confident	77.9	Confident	25 Å²	25	66.6 Å²	66.6	15%	0.152	34%	0.342	C	S	.	.	G	3₁₀ helix	trans	-57.7	-25.9	176.8	-178.4	0	0	0	0	112.2	L250 T251 D255 F256 W261 T382 F386	L250-V253 WeakPolarHBondContact O-CG2 3.05Å; T251-V253 PolarHBondContact O-N 2.75Å; T251-V253 VanDerWaalsContact O-N 3.14Å; V253-D255 VanDerWaalsContact C-N 3.27Å; V253-D255 PolarHBondContact O-N 3.47Å; V253-F256 HydrophobicContact CB-CD2 4.27Å; V253-F256 HydrophobicContact CB-CE2 4.06Å; V253-F256 HydrophobicContact CB-CZ 4.44Å; V253-F256 HydrophobicContact CG1-CD2 3.98Å; V253-F256 HydrophobicContact CG1-CE2 4.01Å; V253-F256 HydrophobicContact CG2-CE2 3.89Å; V253-F256 HydrophobicContact CG2-CZ 4.09Å; V253-W261 HydrophobicContact CG1-CH2 4.12Å; V253-W261 HydrophobicContact CG1-CZ2 4.08Å; V253-T382 HydrophobicContact CG2-CG2 4.17Å; V253-F386 HydrophobicContact CG1-CD2 3.95Å; V253-F386 HydrophobicContact CG1-CE2 3.67Å; V253-F386 HydrophobicContact CG1-CZ 4.24Å; V253-F386 HydrophobicContact CG2-CD2 3.83Å; V253-F386 HydrophobicContact CG2-CE2 4.32Å
254	K	81.3	Confident	80	Confident	182 Å²	182	58.2 Å²	58.2	79%	0.791	31%	0.311	S	S	*	.	G	3₁₀ helix	trans	-71.6	-23	178	-64.9	-179	179.3	179.2	0	113.1	T251 D252	T251-K254 WeakPolarHBondContact O-CB 3.12Å; T251-K254 PolarHBondContact O-N 3.37Å; T251-K254 VanDerWaalsContact O-N 3.1Å; D252-K254 PolarHBondContact O-N 3.44Å; D252-K254 VanDerWaalsContact O-N 3.09Å
255	D	85.4	Confident	82.1	Confident	116 Å²	116	58 Å²	58	62%	0.62	31%	0.306	S	S	*	.	G	3₁₀ helix	trans	-97.8	3.1	-175.1	-57.7	-37.2	0	0	0	112.2	D252 V253 S257	D252-D255 PolarHBondContact O-N 3.3Å; V253-D255 VanDerWaalsContact C-N 3.27Å; V253-D255 PolarHBondContact O-N 3.47Å; D255-S257 PolarHBondContact O-N 2.79Å
256	F	90.1	Very high	84.5	Confident	15 Å²	15	55.2 Å²	55.2	7%	0.066	28%	0.278	C	S	.	.			trans	-64.5	130	-178.6	-73.1	-5.6	0	0	0	112.4	D252 V253 L260 W261 F264 T382 A383 F386	D252-F256 HydrophobicContact CB-CE1 4.46Å; D252-F256 VanDerWaalsContact O-CD1 3.25Å; D252-F256 WeakPolarHBondContact O-CD1 3.42Å; D252-F256 WeakPolarHBondContact O-CE1 3.48Å; V253-F256 HydrophobicContact CB-CD2 4.27Å; V253-F256 HydrophobicContact CB-CE2 4.06Å; V253-F256 HydrophobicContact CB-CZ 4.44Å; V253-F256 HydrophobicContact CG1-CD2 3.98Å; V253-F256 HydrophobicContact CG1-CE2 4.01Å; V253-F256 HydrophobicContact CG2-CE2 3.89Å; V253-F256 HydrophobicContact CG2-CZ 4.09Å; F256-L260 HydrophobicContact CB-CD2 3.88Å; F256-L260 HydrophobicContact CD1-CD2 3.67Å; F256-L260 HydrophobicContact CD2-CD2 3.79Å; F256-L260 HydrophobicContact CE1-CD2 4.07Å; F256-L260 HydrophobicContact CE2-CD2 4.16Å; F256-L260 HydrophobicContact CG-CD2 3.51Å; F256-L260 HydrophobicContact CZ-CD2 4.29Å; F256-W261 HydrophobicContact CD2-CZ2 4.38Å; F256-W261 PolarHBondContact O-NE1 2.91Å; F256-F264 AromaticContact CD2-CE2 3.69Å; F256-F264 HydrophobicContact CD2-CE2 3.69Å; F256-F264 HydrophobicContact CD2-CZ 4.2Å; F256-F264 AromaticContact CE2-CE2 3.8Å; F256-F264 HydrophobicContact CE2-CE2 3.8Å; F256-F264 AromaticContact CE2-CZ 3.99Å; F256-F264 HydrophobicContact CE2-CZ 3.99Å; F256-T382 HydrophobicContact CZ-CG2 4.17Å; F256-A383 HydrophobicContact CE1-CB 4.39Å; F256-A383 HydrophobicContact CZ-CB 4.09Å; F256-F386 HydrophobicContact CE2-CB 4.14Å; F256-F386 HydrophobicContact CE2-CD1 4.42Å; F256-F386 HydrophobicContact CE2-CG 4.11Å
257	S	91.9	Very high	86.4	Confident	34 Å²	34	52 Å²	52	24%	0.238	26%	0.263	C	S	.	.			trans	-67.6	158.3	179.6	77.3	0	0	0	0	112	D255 S259 L260 W261 V374	D255-S257 PolarHBondContact O-N 2.79Å; S257-S259 PolarHBondContact O-N 2.7Å; S257-L260 PolarHBondContact O-N 3Å; S257-L260 VanDerWaalsContact O-N 3.13Å; S257-L260 PolarHBondContact OG-N 3Å; S257-W261 VanDerWaalsContact O-CD1 3.26Å; S257-W261 PolarHBondContact O-N 3.43Å; S257-W261 VanDerWaalsContact O-N 3.13Å; S257-V374 WeakPolarHBondContact OG-CG1 3.5Å
258	L	93.5	Very high	88.1	Confident	94 Å²	94	49.7 Å²	49.7	49%	0.492	25%	0.249	S	C	.	.	H	α-helix	trans	-56.9	-38.2	175	-179.5	61.7	0	0	0	112.3	L260 W261 L262 V435	L258-L260 VanDerWaalsContact C-N 3.31Å; L258-L260 PolarHBondContact O-N 2.92Å; L258-W261 PolarHBondContact O-N 3.18Å; L258-L262 HydrophobicContact CG-CD1 4.13Å; L258-L262 WeakPolarHBondContact O-CG 3.37Å; L258-L262 PolarHBondContact O-N 2.99Å; L258-V435 HydrophobicContact CD2-CG2 3.77Å; L258-V435 HydrophobicContact CG-CG2 4.31Å
259	S	94.6	Very high	89.7	Confident	0 Å²	0	50.6 Å²	50.6	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-61.1	-41.8	177.5	-54.9	0	0	0	0	111.6	S257 L262 I263 V435 E441	S257-S259 PolarHBondContact O-N 2.7Å; S259-L262 PolarHBondContact O-N 3.47Å; S259-I263 VanDerWaalsContact O-CG1 3.31Å; S259-I263 WeakPolarHBondContact O-CG1 3.39Å; S259-I263 PolarHBondContact O-N 3.44Å; S259-V435 WeakPolarHBondContact OG-CG1 3.39Å; S259-E441 WeakPolarHBondContact CB-OE2 3.37Å; S259-E441 PolarHBondContact OG-OE1 2.9Å; S259-E441 PolarHBondContact OG-OE2 3Å
260	L	93.7	Very high	90.9	Very high	1 Å²	1	45 Å²	45	1%	0.005	23%	0.227	C	C	.	.	H	α-helix	trans	-65.6	-41.7	177.3	-171.3	65.3	0	0	0	111.9	F256 S257 L258 L262 I263 F264 V371 V374 V375 A383	F256-L260 HydrophobicContact CB-CD2 3.88Å; F256-L260 HydrophobicContact CD1-CD2 3.67Å; F256-L260 HydrophobicContact CD2-CD2 3.79Å; F256-L260 HydrophobicContact CE1-CD2 4.07Å; F256-L260 HydrophobicContact CE2-CD2 4.16Å; F256-L260 HydrophobicContact CG-CD2 3.51Å; F256-L260 HydrophobicContact CZ-CD2 4.29Å; S257-L260 PolarHBondContact O-N 3Å; S257-L260 VanDerWaalsContact O-N 3.13Å; S257-L260 PolarHBondContact OG-N 3Å; L258-L260 VanDerWaalsContact C-N 3.31Å; L258-L260 PolarHBondContact O-N 2.92Å; L260-L262 VanDerWaalsContact C-N 3.32Å; L260-L262 PolarHBondContact O-N 3.36Å; L260-I263 WeakPolarHBondContact O-CB 3.31Å; L260-I263 PolarHBondContact O-N 3.14Å; L260-F264 HydrophobicContact CD1-CD1 4.46Å; L260-F264 HydrophobicContact CD1-CE1 3.64Å; L260-F264 HydrophobicContact CD1-CZ 3.72Å; L260-F264 HydrophobicContact CD2-CE1 4.46Å; L260-F264 HydrophobicContact CD2-CE2 4.09Å; L260-F264 HydrophobicContact CD2-CZ 3.69Å; L260-F264 HydrophobicContact CG-CE1 3.81Å; L260-F264 HydrophobicContact CG-CE2 3.81Å; L260-F264 HydrophobicContact CG-CZ 3.41Å; L260-F264 VanDerWaalsContact CG-CZ 3.41Å; L260-F264 VanDerWaalsContact O-CG 3.29Å; L260-F264 WeakPolarHBondContact O-CG 3.41Å; L260-F264 PolarHBondContact O-N 3.31Å; L260-V371 HydrophobicContact CD1-CB 4.39Å; L260-V371 HydrophobicContact CD1-CG1 4.06Å; L260-V371 HydrophobicContact CD1-CG2 4.12Å; L260-V374 HydrophobicContact CB-CG1 4.44Å; L260-V375 HydrophobicContact CD1-CG2 3.8Å; L260-V375 HydrophobicContact CD2-CG2 3.48Å; L260-V375 VanDerWaalsContact CD2-CG2 3.48Å; L260-V375 HydrophobicContact CG-CG2 4.2Å; L260-A383 HydrophobicContact CD2-CB 4.23Å
261	W	96.3	Very high	92.1	Very high	91 Å²	91	39.7 Å²	39.7	35%	0.345	20%	0.199	S	C	.	.	H	α-helix	trans	-60.8	-40.1	173.3	-76.9	109.4	0	0	0	112.7	V253 F256 S257 L258 F264 I265 F386	V253-W261 HydrophobicContact CG1-CH2 4.12Å; V253-W261 HydrophobicContact CG1-CZ2 4.08Å; F256-W261 HydrophobicContact CD2-CZ2 4.38Å; F256-W261 PolarHBondContact O-NE1 2.91Å; S257-W261 VanDerWaalsContact O-CD1 3.26Å; S257-W261 PolarHBondContact O-N 3.43Å; S257-W261 VanDerWaalsContact O-N 3.13Å; L258-W261 PolarHBondContact O-N 3.18Å; W261-F264 HydrophobicContact CD2-CD2 4.42Å; W261-F264 AromaticContact CE3-CD2 3.9Å; W261-F264 HydrophobicContact CE3-CD2 3.9Å; W261-F264 HydrophobicContact CZ3-CD2 4.19Å; W261-F264 PolarHBondContact O-N 2.94Å; W261-I265 WeakPolarHBondContact O-CG1 3.41Å; W261-I265 PolarHBondContact O-N 2.63Å; W261-F386 AromaticContact CH2-CE1 3.86Å; W261-F386 HydrophobicContact CH2-CE1 3.86Å; W261-F386 HydrophobicContact CH2-CE2 4.44Å; W261-F386 AromaticContact CH2-CZ 3.58Å; W261-F386 HydrophobicContact CH2-CZ 3.58Å; W261-F386 AromaticContact CZ3-CE1 3.61Å; W261-F386 HydrophobicContact CZ3-CE1 3.61Å; W261-F386 AromaticContact CZ3-CZ 3.7Å; W261-F386 HydrophobicContact CZ3-CZ 3.7Å
262	L	97.1	Very high	93	Very high	22 Å²	22	35.6 Å²	35.6	12%	0.115	17%	0.174	C	C	.	.	H	α-helix	trans	-64.9	-41	174.9	-69.4	166.8	0	0	0	111.4	L258 S259 L260 F264 I265 I266 A428 L432 V435	L258-L262 HydrophobicContact CG-CD1 4.13Å; L258-L262 WeakPolarHBondContact O-CG 3.37Å; L258-L262 PolarHBondContact O-N 2.99Å; S259-L262 PolarHBondContact O-N 3.47Å; L260-L262 VanDerWaalsContact C-N 3.32Å; L260-L262 PolarHBondContact O-N 3.36Å; L262-F264 VanDerWaalsContact C-N 3.3Å; L262-F264 PolarHBondContact O-N 2.85Å; L262-I265 PolarHBondContact O-N 3.32Å; L262-I266 WeakPolarHBondContact O-CD1 3.25Å; L262-I266 WeakPolarHBondContact O-CG1 3.48Å; L262-I266 PolarHBondContact O-N 3.25Å; L262-A428 HydrophobicContact CD2-CB 4.24Å; L262-L432 HydrophobicContact CB-CB 4.2Å; L262-L432 HydrophobicContact CB-CD1 4.24Å; L262-L432 HydrophobicContact CD1-CB 4.28Å; L262-V435 HydrophobicContact CD1-CG2 3.95Å
263	I	96.6	Very high	94	Very high	0 Å²	0	35 Å²	35	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-57.8	-43	172.9	-70	165	0	0	0	110.9	S259 L260 I266 C267 L367 M370 V371 V374 M387 L432	S259-I263 VanDerWaalsContact O-CG1 3.31Å; S259-I263 WeakPolarHBondContact O-CG1 3.39Å; S259-I263 PolarHBondContact O-N 3.44Å; L260-I263 WeakPolarHBondContact O-CB 3.31Å; L260-I263 PolarHBondContact O-N 3.14Å; I263-I266 PolarHBondContact O-N 2.95Å; I263-C267 WeakPolarHBondContact O-CB 3.15Å; I263-C267 PolarHBondContact O-N 3.47Å; I263-L367 HydrophobicContact CG2-CD1 3.91Å; I263-L367 HydrophobicContact CG2-CG 4.3Å; I263-M370 HydrophobicContact CD1-CB 3.78Å; I263-V371 HydrophobicContact CG2-CG2 4.01Å; I263-V374 HydrophobicContact CD1-CG2 4.29Å; I263-M387 HydrophobicContact CG2-CE 4.41Å; I263-M387 HydrophobicContact CG2-SD 4.49Å; I263-L432 HydrophobicContact CG1-CD1 4.3Å; I263-L432 HydrophobicContact CG1-CD2 3.82Å
264	F	96.7	Very high	94.8	Very high	1 Å²	1	33.8 Å²	33.8	0%	0.004	16%	0.163	C	C	.	.	H	α-helix	trans	-64.4	-42.6	176.6	-61.3	-19.9	0	0	0	112.6	F256 L260 W261 L262 C267 V268 F386 M387 I390	F256-F264 AromaticContact CD2-CE2 3.69Å; F256-F264 HydrophobicContact CD2-CE2 3.69Å; F256-F264 HydrophobicContact CD2-CZ 4.2Å; F256-F264 AromaticContact CE2-CE2 3.8Å; F256-F264 HydrophobicContact CE2-CE2 3.8Å; F256-F264 AromaticContact CE2-CZ 3.99Å; F256-F264 HydrophobicContact CE2-CZ 3.99Å; L260-F264 HydrophobicContact CD1-CD1 4.46Å; L260-F264 HydrophobicContact CD1-CE1 3.64Å; L260-F264 HydrophobicContact CD1-CZ 3.72Å; L260-F264 HydrophobicContact CD2-CE1 4.46Å; L260-F264 HydrophobicContact CD2-CE2 4.09Å; L260-F264 HydrophobicContact CD2-CZ 3.69Å; L260-F264 HydrophobicContact CG-CE1 3.81Å; L260-F264 HydrophobicContact CG-CE2 3.81Å; L260-F264 HydrophobicContact CG-CZ 3.41Å; L260-F264 VanDerWaalsContact CG-CZ 3.41Å; L260-F264 VanDerWaalsContact O-CG 3.29Å; L260-F264 WeakPolarHBondContact O-CG 3.41Å; L260-F264 PolarHBondContact O-N 3.31Å; W261-F264 HydrophobicContact CD2-CD2 4.42Å; W261-F264 AromaticContact CE3-CD2 3.9Å; W261-F264 HydrophobicContact CE3-CD2 3.9Å; W261-F264 HydrophobicContact CZ3-CD2 4.19Å; W261-F264 PolarHBondContact O-N 2.94Å; L262-F264 VanDerWaalsContact C-N 3.3Å; L262-F264 PolarHBondContact O-N 2.85Å; F264-C267 WeakPolarHBondContact O-CB 3.18Å; F264-C267 PolarHBondContact O-N 3.45Å; F264-V268 WeakPolarHBondContact O-CG2 3.49Å; F264-V268 PolarHBondContact O-N 3.38Å; F264-F386 AromaticContact CD2-CD1 3.52Å; F264-F386 HydrophobicContact CD2-CD1 3.52Å; F264-F386 AromaticContact CD2-CE1 3.6Å; F264-F386 HydrophobicContact CD2-CE1 3.6Å; F264-F386 AromaticContact CE2-CD1 3.26Å; F264-F386 HydrophobicContact CE2-CD1 3.26Å; F264-F386 AromaticContact CE2-CE1 3.72Å; F264-F386 HydrophobicContact CE2-CE1 3.72Å; F264-F386 HydrophobicContact CE2-CG 4.17Å; F264-F386 HydrophobicContact CG-CD1 4.27Å; F264-F386 HydrophobicContact CG-CE1 4.46Å; F264-F386 HydrophobicContact CZ-CB 4.4Å; F264-F386 AromaticContact CZ-CD1 3.82Å; F264-F386 HydrophobicContact CZ-CD1 3.82Å; F264-F386 HydrophobicContact CZ-CG 4.5Å; F264-M387 HydrophobicContact CD1-CB 3.83Å; F264-M387 HydrophobicContact CD1-CG 3.91Å; F264-M387 HydrophobicContact CE1-CB 3.64Å; F264-M387 HydrophobicContact CE1-CG 4.14Å; F264-I390 HydrophobicContact CB-CG2 4.36Å
265	I	98.1	Very high	95.5	Very high	65 Å²	65	26.4 Å²	26.4	33%	0.333	13%	0.131	S	C	.	.	H	α-helix	trans	-61	-46.9	175.8	-68.3	167.6	0	0	0	110.3	W261 L262 C267 V268 F269 I424 A428	W261-I265 WeakPolarHBondContact O-CG1 3.41Å; W261-I265 PolarHBondContact O-N 2.63Å; L262-I265 PolarHBondContact O-N 3.32Å; I265-C267 VanDerWaalsContact C-N 3.32Å; I265-C267 PolarHBondContact O-N 3Å; I265-V268 PolarHBondContact O-N 3.07Å; I265-F269 HydrophobicContact CG2-CD2 3.73Å; I265-F269 HydrophobicContact CG2-CE2 4.08Å; I265-F269 WeakPolarHBondContact O-CD2 3.42Å; I265-F269 PolarHBondContact O-N 3.46Å; I265-I424 HydrophobicContact CG2-CG2 4.2Å; I265-A428 HydrophobicContact CB-CB 4.16Å; I265-A428 HydrophobicContact CG2-CB 3.64Å
266	I	98.4	Very high	96	Very high	0 Å²	0	21.1 Å²	21.1	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-57.6	-47.7	176.6	-63.4	158.3	0	0	0	110.1	L262 I263 V268 Y270 V328 L363 L367 A428 V429 L432	L262-I266 WeakPolarHBondContact O-CD1 3.25Å; L262-I266 WeakPolarHBondContact O-CG1 3.48Å; L262-I266 PolarHBondContact O-N 3.25Å; I263-I266 PolarHBondContact O-N 2.95Å; I266-V268 PolarHBondContact O-N 3.27Å; I266-Y270 WeakPolarHBondContact O-CB 3.46Å; I266-Y270 PolarHBondContact O-N 3.23Å; I266-V328 HydrophobicContact CG2-CG1 3.88Å; I266-L363 HydrophobicContact CG2-CD1 4.36Å; I266-L367 HydrophobicContact CB-CD1 4.16Å; I266-L367 HydrophobicContact CD1-CD1 4.48Å; I266-L367 HydrophobicContact CG2-CD1 3.84Å; I266-L367 HydrophobicContact CG2-CD2 4.06Å; I266-A428 HydrophobicContact CD1-CB 4.39Å; I266-A428 HydrophobicContact CG1-CB 3.61Å; I266-V429 HydrophobicContact CD1-CB 4.28Å; I266-V429 HydrophobicContact CD1-CG2 3.65Å; I266-V429 HydrophobicContact CG1-CG2 3.73Å; I266-V429 HydrophobicContact CG2-CG2 3.98Å; I266-L432 HydrophobicContact CD1-CB 4.4Å; I266-L432 HydrophobicContact CD1-CD2 3.85Å
267	C	97.3	Very high	96.3	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-55.1	-55.6	179.9	-175.4	0	0	0	0	111.8	I263 F264 I265 Y271 L367 M387	I263-C267 WeakPolarHBondContact O-CB 3.15Å; I263-C267 PolarHBondContact O-N 3.47Å; F264-C267 WeakPolarHBondContact O-CB 3.18Å; F264-C267 PolarHBondContact O-N 3.45Å; I265-C267 VanDerWaalsContact C-N 3.32Å; I265-C267 PolarHBondContact O-N 3Å; C267-Y271 WeakPolarHBondContact O-CD2 3.07Å; C267-Y271 PolarHBondContact O-N 3.42Å; C267-Y271 VanDerWaalsContact SG-CD2 3.59Å; C267-L367 HydrophobicContact CB-CD2 3.89Å; C267-M387 HydrophobicContact CB-CE 3.73Å; C267-M387 HydrophobicContact CB-CG 4.31Å; C267-M387 WeakPolarHBondContact SG-CE 3.37Å
268	V	97.5	Very high	96.4	Very high	19 Å²	19	18.9 Å²	18.9	12%	0.115	9%	0.089	C	C	.	.	H	α-helix	trans	-61.2	-58.1	-176.7	175.4	0	0	0	0	110.4	F264 I265 I266 Y270 Y271 V272 I390	F264-V268 WeakPolarHBondContact O-CG2 3.49Å; F264-V268 PolarHBondContact O-N 3.38Å; I265-V268 PolarHBondContact O-N 3.07Å; I266-V268 PolarHBondContact O-N 3.27Å; V268-Y270 PolarHBondContact O-N 2.92Å; V268-Y271 PolarHBondContact O-N 3.07Å; V268-V272 HydrophobicContact CG1-CG1 4.2Å; V268-V272 VanDerWaalsContact O-CG1 3.22Å; V268-V272 WeakPolarHBondContact O-CG1 3.38Å; V268-V272 WeakPolarHBondContact O-CG2 3.41Å; V268-V272 PolarHBondContact O-N 3.27Å; V268-I390 HydrophobicContact CG2-CB 4.18Å; V268-I390 HydrophobicContact CG2-CD1 4.32Å; V268-I390 HydrophobicContact CG2-CG1 3.86Å; V268-I390 HydrophobicContact CG2-CG2 3.68Å
269	F	98.2	Very high	96.3	Very high	61 Å²	61	14.5 Å²	14.5	27%	0.268	7%	0.066	S	C	.	.	H	α-helix	trans	-67.7	-24.8	-172.2	-79.9	-75.4	0	0	0	113.4	I265 C421 I424 A425	I265-F269 HydrophobicContact CG2-CD2 3.73Å; I265-F269 HydrophobicContact CG2-CE2 4.08Å; I265-F269 WeakPolarHBondContact O-CD2 3.42Å; I265-F269 PolarHBondContact O-N 3.46Å; F269-C421 WeakPolarHBondContact CB-O 3.19Å; F269-C421 HydrophobicContact CD1-CB 4.1Å; F269-I424 HydrophobicContact CB-CB 4.46Å; F269-I424 HydrophobicContact CB-CG2 4.49Å; F269-I424 HydrophobicContact CD1-CB 3.98Å; F269-I424 HydrophobicContact CD1-CD1 3.89Å; F269-I424 HydrophobicContact CD1-CG2 4.05Å; F269-I424 HydrophobicContact CD2-CB 4.29Å; F269-I424 HydrophobicContact CD2-CG2 3.54Å; F269-I424 HydrophobicContact CE1-CB 4.28Å; F269-I424 HydrophobicContact CE1-CD1 3.47Å; F269-I424 VanDerWaalsContact CE1-CD1 3.47Å; F269-I424 HydrophobicContact CE1-CG1 4.48Å; F269-I424 HydrophobicContact CE1-CG2 4.12Å; F269-I424 HydrophobicContact CE2-CG2 3.62Å; F269-I424 HydrophobicContact CG-CB 3.98Å; F269-I424 HydrophobicContact CG-CG2 3.76Å; F269-I424 HydrophobicContact CZ-CD1 3.94Å; F269-I424 HydrophobicContact CZ-CG2 3.91Å; F269-A425 HydrophobicContact CB-CB 4.02Å
270	Y	98.2	Very high	96.3	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-73.1	-56.2	171	-172.9	-91	0	0	0	112	I266 V268 V272 A273 I274 V332 T335 S359 Y360 L363 I422	I266-Y270 WeakPolarHBondContact O-CB 3.46Å; I266-Y270 PolarHBondContact O-N 3.23Å; V268-Y270 PolarHBondContact O-N 2.92Å; Y270-V272 VanDerWaalsContact C-N 3.31Å; Y270-V272 PolarHBondContact O-N 2.99Å; Y270-A273 PolarHBondContact O-N 3.42Å; Y270-A273 VanDerWaalsContact O-N 3.12Å; Y270-I274 HydrophobicContact CD1-CG1 4.12Å; Y270-I274 HydrophobicContact CE1-CD1 4.29Å; Y270-I274 HydrophobicContact CE1-CG1 3.79Å; Y270-I274 PolarHBondContact O-N 3.33Å; Y270-V332 HydrophobicContact CD2-CG2 4Å; Y270-V332 HydrophobicContact CE2-CG2 4.35Å; Y270-T335 HydrophobicContact CE2-CG2 3.87Å; Y270-T335 WeakPolarHBondContact CE2-OG1 3.49Å; Y270-T335 VanDerWaalsContact CZ-OG1 3.28Å; Y270-T335 PolarHBondContact OH-OG1 3.05Å; Y270-S359 PolarHBondContact OH-O 2.96Å; Y270-S359 PolarHBondContact OH-OG 2.94Å; Y270-Y360 HydrophobicContact CE1-CD2 4.32Å; Y270-Y360 VanDerWaalsContact OH-CA 3.29Å; Y270-Y360 WeakPolarHBondContact OH-CA 3.49Å; Y270-Y360 PolarHBondContact OH-N 2.89Å; Y270-Y360 VanDerWaalsContact OH-N 3.16Å; Y270-L363 HydrophobicContact CD1-CB 4.4Å; Y270-L363 HydrophobicContact CD1-CD1 4.07Å; Y270-L363 HydrophobicContact CD1-CD2 3.21Å; Y270-L363 HydrophobicContact CD1-CG 4.03Å; Y270-L363 HydrophobicContact CD2-CD1 3.6Å; Y270-L363 HydrophobicContact CD2-CD2 4.34Å; Y270-L363 HydrophobicContact CD2-CG 4.42Å; Y270-L363 HydrophobicContact CE1-CB 3.85Å; Y270-L363 HydrophobicContact CE1-CD1 4.19Å; Y270-L363 HydrophobicContact CE1-CD2 3.51Å; Y270-L363 HydrophobicContact CE1-CG 4.01Å; Y270-L363 HydrophobicContact CE2-CB 4.35Å; Y270-L363 HydrophobicContact CE2-CD1 3.73Å; Y270-L363 HydrophobicContact CE2-CG 4.39Å; Y270-L363 HydrophobicContact CG-CD1 3.74Å; Y270-L363 HydrophobicContact CG-CD2 3.66Å; Y270-L363 HydrophobicContact CG-CG 4.22Å; Y270-I422 HydrophobicContact CD2-CD1 4.01Å
271	Y	96.9	Very high	96.3	Very high	7 Å²	7	14.4 Å²	14.4	3%	0.027	7%	0.066	C	C	.	.	H	α-helix	trans	-69.2	-28.1	-172.6	-74.9	-60.2	0	0	0	113.6	C267 V268 A273 I274 F275 Y360 L363 W368 Q391	C267-Y271 WeakPolarHBondContact O-CD2 3.07Å; C267-Y271 PolarHBondContact O-N 3.42Å; C267-Y271 VanDerWaalsContact SG-CD2 3.59Å; V268-Y271 PolarHBondContact O-N 3.07Å; Y271-A273 PolarHBondContact O-N 2.92Å; Y271-I274 PolarHBondContact O-N 3.09Å; Y271-I274 VanDerWaalsContact O-N 3.13Å; Y271-F275 HydrophobicContact CD1-CD2 4.16Å; Y271-F275 AromaticContact CD1-CE2 3.56Å; Y271-F275 HydrophobicContact CD1-CE2 3.56Å; Y271-F275 HydrophobicContact CD1-CZ 4.4Å; Y271-F275 HydrophobicContact CE1-CE2 4.31Å; Y271-F275 HydrophobicContact CG-CD2 4.46Å; Y271-F275 HydrophobicContact CG-CE2 4.06Å; Y271-F275 PolarHBondContact O-N 3.35Å; Y271-Y360 AromaticContact CD1-CE2 3.9Å; Y271-Y360 HydrophobicContact CD1-CE2 3.9Å; Y271-Y360 HydrophobicContact CE1-CD2 4.09Å; Y271-Y360 AromaticContact CE1-CE2 3.51Å; Y271-Y360 HydrophobicContact CE1-CE2 3.51Å; Y271-L363 HydrophobicContact CE1-CD2 4.4Å; Y271-L363 HydrophobicContact CE2-CD2 4.12Å; Y271-W368 HydrophobicContact CE2-CZ2 4.32Å; Y271-W368 AromaticContact CE2-NE1 3.67Å; Y271-W368 AromaticContact CZ-NE1 3.69Å; Y271-W368 PolarHBondContact OH-NE1 2.99Å; Y271-Q391 HydrophobicContact CD2-CG 4.22Å; Y271-Q391 VanDerWaalsContact CD2-NE2 3.28Å
272	V	96.6	Very high	96	Very high	1 Å²	1	10.1 Å²	10.1	1%	0.006	5%	0.05	C	C	.	.	H	α-helix	trans	-70.1	-16.1	174.6	-61.1	0	0	0	0	113.7	V268 Y270 P276 G394 L395 I398 F418 C421	V268-V272 HydrophobicContact CG1-CG1 4.2Å; V268-V272 VanDerWaalsContact O-CG1 3.22Å; V268-V272 WeakPolarHBondContact O-CG1 3.38Å; V268-V272 WeakPolarHBondContact O-CG2 3.41Å; V268-V272 PolarHBondContact O-N 3.27Å; Y270-V272 VanDerWaalsContact C-N 3.31Å; Y270-V272 PolarHBondContact O-N 2.99Å; V272-P276 WeakPolarHBondContact O-CD 3.33Å; V272-P276 VanDerWaalsContact O-CG 3.23Å; V272-P276 WeakPolarHBondContact O-CG 3.06Å; V272-G394 VanDerWaalsContact CG1-C 3.42Å; V272-L395 HydrophobicContact CG1-CD2 4.2Å; V272-I398 HydrophobicContact CB-CB 3.99Å; V272-I398 HydrophobicContact CB-CG1 3.86Å; V272-I398 HydrophobicContact CB-CG2 3.98Å; V272-I398 HydrophobicContact CG1-CB 4.2Å; V272-I398 HydrophobicContact CG1-CG1 3.91Å; V272-I398 HydrophobicContact CG2-CG1 4.17Å; V272-F418 WeakPolarHBondContact O-CE1 3.24Å; V272-C421 HydrophobicContact CG2-CB 4.33Å
273	A	96.8	Very high	95.8	Very high	0 Å²	0	10.1 Å²	10.1	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-86.6	-24.8	169.7	0	0	0	0	0	112.4	Y270 Y271 F277 H339 F418 I422	Y270-A273 PolarHBondContact O-N 3.42Å; Y270-A273 VanDerWaalsContact O-N 3.12Å; Y271-A273 PolarHBondContact O-N 2.92Å; A273-F277 WeakPolarHBondContact O-CB 3.4Å; A273-H339 PolarHBondContact O-NE2 2.97Å; A273-F418 HydrophobicContact CB-CB 4.12Å; A273-F418 HydrophobicContact CB-CD1 4.11Å; A273-F418 HydrophobicContact CB-CG 4.35Å; A273-I422 HydrophobicContact CB-CD1 3.47Å; A273-I422 VanDerWaalsContact CB-CD1 3.47Å; A273-I422 HydrophobicContact CB-CG1 3.72Å
274	I	95.9	Very high	95.8	Very high	0 Å²	0	10.2 Å²	10.2	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-85.4	-60.6	-178.1	-56.9	-60.4	0	0	0	111.8	Y270 Y271 F277 I278 T335 L356 Y360	Y270-I274 HydrophobicContact CD1-CG1 4.12Å; Y270-I274 HydrophobicContact CE1-CD1 4.29Å; Y270-I274 HydrophobicContact CE1-CG1 3.79Å; Y270-I274 PolarHBondContact O-N 3.33Å; Y271-I274 PolarHBondContact O-N 3.09Å; Y271-I274 VanDerWaalsContact O-N 3.13Å; I274-F277 WeakPolarHBondContact O-CB 3.43Å; I274-F277 PolarHBondContact O-N 3.48Å; I274-I278 HydrophobicContact CG2-CD1 3.77Å; I274-I278 WeakPolarHBondContact O-CG1 3.35Å; I274-I278 PolarHBondContact O-N 3.39Å; I274-T335 HydrophobicContact CD1-CG2 3.8Å; I274-L356 HydrophobicContact CD1-CD1 3.39Å; I274-L356 HydrophobicContact CD1-CD2 4.39Å; I274-L356 HydrophobicContact CD1-CG 3.95Å; I274-Y360 HydrophobicContact CG1-CD2 4.33Å; I274-Y360 HydrophobicContact CG2-CD2 3.9Å; I274-Y360 HydrophobicContact CG2-CE2 4.03Å
275	F	94.9	Very high	95.8	Very high	28 Å²	28	10.2 Å²	10.2	12%	0.123	5%	0.051	C	C	.	.	H	α-helix	trans	-70	-46.3	-167.8	-69.6	-70.6	0	0	0	113.3	Y271 F277 I278 G279 Y360 L395	Y271-F275 HydrophobicContact CD1-CD2 4.16Å; Y271-F275 AromaticContact CD1-CE2 3.56Å; Y271-F275 HydrophobicContact CD1-CE2 3.56Å; Y271-F275 HydrophobicContact CD1-CZ 4.4Å; Y271-F275 HydrophobicContact CE1-CE2 4.31Å; Y271-F275 HydrophobicContact CG-CD2 4.46Å; Y271-F275 HydrophobicContact CG-CE2 4.06Å; Y271-F275 PolarHBondContact O-N 3.35Å; F275-F277 VanDerWaalsContact C-N 3.25Å; F275-F277 PolarHBondContact O-N 2.96Å; F275-I278 PolarHBondContact O-N 2.87Å; F275-G279 PolarHBondContact O-N 3.16Å; F275-Y360 HydrophobicContact CZ-CE2 4.3Å; F275-Y360 WeakPolarHBondContact CZ-OH 3.48Å; F275-L395 HydrophobicContact CB-CD2 3.82Å; F275-L395 HydrophobicContact CD2-CD1 4.18Å; F275-L395 HydrophobicContact CD2-CD2 3.99Å; F275-L395 HydrophobicContact CG-CD2 4.36Å
276	P	96.3	Very high	95.6	Very high	5 Å²	5	8.9 Å²	8.9	3%	0.032	4%	0.044	C	C	.	.	H	α-helix	trans	-61.1	-34	173.5	-26.1	38.4	0	0	0	113	M76 V272 G279 Q280 L395 I398 V402 F418	M76-P276 HydrophobicContact CE-CB 3.93Å; V272-P276 WeakPolarHBondContact O-CD 3.33Å; V272-P276 VanDerWaalsContact O-CG 3.23Å; V272-P276 WeakPolarHBondContact O-CG 3.06Å; P276-G279 PolarHBondContact O-N 2.94Å; P276-Q280 PolarHBondContact O-N 3.44Å; P276-Q280 VanDerWaalsContact O-N 3.16Å; P276-L395 HydrophobicContact CG-CD2 4.23Å; P276-I398 HydrophobicContact CG-CG2 4.18Å; P276-V402 HydrophobicContact CB-CG2 3.93Å; P276-F418 HydrophobicContact CB-CE1 4.21Å; P276-F418 HydrophobicContact CB-CZ 4.1Å
277	F	96.4	Very high	95.3	Very high	1 Å²	1	15 Å²	15	0%	0.004	7%	0.073	C	C	.	.	H	α-helix	trans	-65.1	-47.5	173.9	173.3	-102.2	0	0	0	111.7	A273 I274 F275 G279 Q280 G281 F284 F285 H339 L342 M353 L356 E415 F418	A273-F277 WeakPolarHBondContact O-CB 3.4Å; I274-F277 WeakPolarHBondContact O-CB 3.43Å; I274-F277 PolarHBondContact O-N 3.48Å; F275-F277 VanDerWaalsContact C-N 3.25Å; F275-F277 PolarHBondContact O-N 2.96Å; F277-G279 PolarHBondContact O-N 2.83Å; F277-Q280 CarbonylContact O-C 3.46Å; F277-Q280 PolarHBondContact O-N 2.96Å; F277-G281 WeakPolarHBondContact O-CA 3.35Å; F277-G281 PolarHBondContact O-N 3.25Å; F277-F284 HydrophobicContact CE2-CD1 4.09Å; F277-F284 HydrophobicContact CE2-CE1 4.3Å; F277-F284 HydrophobicContact CE2-CG 4.42Å; F277-F284 HydrophobicContact CZ-CD1 4.34Å; F277-F284 HydrophobicContact CZ-CE1 4.49Å; F277-F285 HydrophobicContact CE1-CZ 4.49Å; F277-F285 AromaticContact CZ-CZ 3.91Å; F277-F285 HydrophobicContact CZ-CZ 3.91Å; F277-H339 AromaticContact CG-CE1 3.89Å; F277-L342 HydrophobicContact CE1-CD1 4.1Å; F277-L342 HydrophobicContact CE2-CD1 4.16Å; F277-L342 HydrophobicContact CZ-CD1 3.57Å; F277-M353 HydrophobicContact CE1-CE 3.67Å; F277-M353 HydrophobicContact CE1-SD 3.51Å; F277-M353 VanDerWaalsContact CE1-SD 3.51Å; F277-M353 HydrophobicContact CZ-CE 4.4Å; F277-M353 HydrophobicContact CZ-SD 3.97Å; F277-L356 HydrophobicContact CD1-CD2 3.97Å; F277-L356 HydrophobicContact CE1-CD2 3.96Å; F277-E415 WeakPolarHBondContact CD2-OE1 3.34Å; F277-E415 WeakPolarHBondContact CE2-OE1 3.44Å; F277-F418 HydrophobicContact CB-CD2 4.12Å; F277-F418 HydrophobicContact CB-CE2 3.58Å; F277-F418 HydrophobicContact CB-CZ 3.96Å; F277-F418 HydrophobicContact CD2-CD2 4.26Å; F277-F418 AromaticContact CD2-CE2 3.95Å; F277-F418 HydrophobicContact CD2-CE2 3.95Å; F277-F418 HydrophobicContact CG-CE2 4.23Å
278	I	94.2	Very high	95.2	Very high	1 Å²	1	16.9 Å²	16.9	1%	0.005	8%	0.081	C	C	.	.	H	α-helix	trans	-58.3	-38	174.4	-66.4	168.7	0	0	0	110.6	M183 I274 F275 Q280 G281 N300 V303 Y304	M183-I278 HydrophobicContact CE-CG2 4.37Å; I274-I278 HydrophobicContact CG2-CD1 3.77Å; I274-I278 WeakPolarHBondContact O-CG1 3.35Å; I274-I278 PolarHBondContact O-N 3.39Å; F275-I278 PolarHBondContact O-N 2.87Å; I278-Q280 PolarHBondContact O-N 2.91Å; I278-G281 PolarHBondContact O-N 2.89Å; I278-N300 PolarHBondContact O-ND2 2.94Å; I278-V303 HydrophobicContact CD1-CG1 4.09Å; I278-Y304 HydrophobicContact CD1-CE1 3.92Å; I278-Y304 HydrophobicContact CD1-CE2 4.45Å; I278-Y304 HydrophobicContact CG2-CE2 4.01Å
279	G	92.2	Very high	95.1	Very high	1 Å²	1	17.2 Å²	17.2	1%	0.01	8%	0.081	C	C	.	.	H	α-helix	trans	-51.9	-39.7	171.7	0	0	0	0	0	113.9	Q61 F275 P276 F277	Q61-G279 PolarHBondContact OE1-O 3.23Å; F275-G279 PolarHBondContact O-N 3.16Å; P276-G279 PolarHBondContact O-N 2.94Å; F277-G279 PolarHBondContact O-N 2.83Å
280	Q	93.9	Very high	94.9	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-103.8	-7.9	-174.2	-69.8	-67	106.2	0	0	114.5	M76 P276 F277 I278 Q282 V283 F284 V402 L414	M76-Q280 HydrophobicContact CE-CG 3.73Å; M76-Q280 HydrophobicContact SD-CG 3.77Å; M76-Q280 PolarHBondContact SD-OE1 3.04Å; P276-Q280 PolarHBondContact O-N 3.44Å; P276-Q280 VanDerWaalsContact O-N 3.16Å; F277-Q280 CarbonylContact O-C 3.46Å; F277-Q280 PolarHBondContact O-N 2.96Å; I278-Q280 PolarHBondContact O-N 2.91Å; Q280-Q282 VanDerWaalsContact C-N 3.31Å; Q280-Q282 PolarHBondContact O-N 3.5Å; Q280-V283 PolarHBondContact O-N 3.18Å; Q280-F284 WeakPolarHBondContact O-CB 3.46Å; Q280-F284 PolarHBondContact O-N 3.45Å; Q280-F284 VanDerWaalsContact O-N 3.12Å; Q280-V402 HydrophobicContact CG-CG1 3.82Å; Q280-L414 HydrophobicContact CB-CD2 4.48Å
281	G	92.8	Very high	94.8	Very high	0 Å²	0	23 Å²	23	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-61.8	-36.7	-165.8	0	0	0	0	0	112.9	F277 I278 F284 F285	F277-G281 WeakPolarHBondContact O-CA 3.35Å; F277-G281 PolarHBondContact O-N 3.25Å; I278-G281 PolarHBondContact O-N 2.89Å; G281-F284 WeakPolarHBondContact O-CB 3.35Å; G281-F284 PolarHBondContact O-N 3.4Å; G281-F285 WeakPolarHBondContact O-CD2 3.34Å; G281-F285 WeakPolarHBondContact O-CE2 3.26Å; G281-F285 WeakPolarHBondContact O-CG 3.2Å; G281-F285 PolarHBondContact O-N 3.45Å
282	Q	91.7	Very high	94.6	Very high	0 Å²	0	25 Å²	25	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-59.5	-55.8	-178.8	179.5	179.4	-47.4	0	0	111.5	A58 A59 T62 Q280 F284 F285 I286 A296 R297	A58-Q282 PolarHBondContact O-OE1 3.3Å; A59-Q282 PolarHBondContact O-OE1 3.34Å; T62-Q282 PolarHBondContact OG1-NE2 3.14Å; T62-Q282 VanDerWaalsContact OG1-NE2 3.07Å; Q280-Q282 VanDerWaalsContact C-N 3.31Å; Q280-Q282 PolarHBondContact O-N 3.5Å; Q282-F284 VanDerWaalsContact C-N 3.31Å; Q282-F284 PolarHBondContact O-N 3.04Å; Q282-F285 PolarHBondContact O-N 3.49Å; Q282-I286 HydrophobicContact CG-CD1 4.03Å; Q282-I286 VanDerWaalsContact O-CG1 3.31Å; Q282-I286 WeakPolarHBondContact O-CG1 3.28Å; Q282-I286 PolarHBondContact O-N 2.88Å; Q282-A296 HydrophobicContact CG-CB 4.05Å; Q282-A296 WeakPolarHBondContact O-CB 3.39Å; Q282-R297 HydrophobicContact CG-CG 4.19Å
283	V	92.4	Very high	94.3	Very high	23 Å²	23	27.8 Å²	27.8	14%	0.139	15%	0.146	C	C	.	.	H	α-helix	trans	-67.3	-35.9	-179.5	179.7	0	0	0	0	110.7	Q61 Q280 F285 I286 E287 Y411	Q61-V283 HydrophobicContact CB-CG2 4.45Å; Q61-V283 VanDerWaalsContact CD-CG2 3.41Å; Q61-V283 HydrophobicContact CG-CG2 3.8Å; Q280-V283 PolarHBondContact O-N 3.18Å; V283-F285 PolarHBondContact O-N 2.86Å; V283-I286 PolarHBondContact O-N 3.26Å; V283-E287 HydrophobicContact CG1-CG 3.86Å; V283-E287 WeakPolarHBondContact O-CB 3.43Å; V283-E287 WeakPolarHBondContact O-CG 3.48Å; V283-E287 PolarHBondContact O-N 3.08Å; V283-Y411 WeakPolarHBondContact CB-OH 3.37Å; V283-Y411 HydrophobicContact CG1-CE2 4.23Å; V283-Y411 WeakPolarHBondContact CG1-OH 3.39Å
284	F	95.7	Very high	93.9	Very high	2 Å²	2	30.5 Å²	30.5	1%	0.009	17%	0.169	C	C	.	.	H	α-helix	trans	-53.6	-48.7	172.9	171.2	-98.3	0	0	0	112.9	F277 Q280 G281 Q282 K288 F289 L342 Y411 E415	F277-F284 HydrophobicContact CE2-CD1 4.09Å; F277-F284 HydrophobicContact CE2-CE1 4.3Å; F277-F284 HydrophobicContact CE2-CG 4.42Å; F277-F284 HydrophobicContact CZ-CD1 4.34Å; F277-F284 HydrophobicContact CZ-CE1 4.49Å; Q280-F284 WeakPolarHBondContact O-CB 3.46Å; Q280-F284 PolarHBondContact O-N 3.45Å; Q280-F284 VanDerWaalsContact O-N 3.12Å; G281-F284 WeakPolarHBondContact O-CB 3.35Å; G281-F284 PolarHBondContact O-N 3.4Å; Q282-F284 VanDerWaalsContact C-N 3.31Å; Q282-F284 PolarHBondContact O-N 3.04Å; F284-K288 HydrophobicContact CE2-CB 4.43Å; F284-K288 HydrophobicContact CE2-CD 3.88Å; F284-K288 HydrophobicContact CZ-CD 3.72Å; F284-K288 VanDerWaalsContact O-CB 3.3Å; F284-K288 WeakPolarHBondContact O-CB 3.17Å; F284-K288 PolarHBondContact O-N 3.35Å; F284-F289 HydrophobicContact CE1-CD2 4.33Å; F284-F289 AromaticContact CE1-CE2 3.75Å; F284-F289 HydrophobicContact CE1-CE2 3.75Å; F284-F289 HydrophobicContact CZ-CE2 4.05Å; F284-L342 HydrophobicContact CE1-CB 4.37Å; F284-L342 HydrophobicContact CE1-CD2 4.03Å; F284-L342 HydrophobicContact CZ-CB 4.15Å; F284-Y411 HydrophobicContact CB-CD1 3.84Å; F284-Y411 HydrophobicContact CB-CE1 3.88Å; F284-Y411 HydrophobicContact CB-CG 4.5Å; F284-Y411 AromaticContact CD2-CD1 3.62Å; F284-Y411 HydrophobicContact CD2-CD1 3.62Å; F284-Y411 HydrophobicContact CD2-CE1 4.49Å; F284-Y411 AromaticContact CD2-CG 3.79Å; F284-Y411 HydrophobicContact CD2-CG 3.79Å; F284-Y411 HydrophobicContact CG-CD1 4.24Å; F284-E415 HydrophobicContact CE2-CG 3.83Å; F284-E415 HydrophobicContact CZ-CG 4.08Å
285	F	96.4	Very high	93.8	Very high	0 Å²	0	35.1 Å²	35.1	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-70.2	-31.6	-179.6	-64.9	-55.8	0	0	0	113.1	F277 G281 Q282 V283 F289 N290 F291 A296 V299 N300 L342 P349 M353	F277-F285 HydrophobicContact CE1-CZ 4.49Å; F277-F285 AromaticContact CZ-CZ 3.91Å; F277-F285 HydrophobicContact CZ-CZ 3.91Å; G281-F285 WeakPolarHBondContact O-CD2 3.34Å; G281-F285 WeakPolarHBondContact O-CE2 3.26Å; G281-F285 WeakPolarHBondContact O-CG 3.2Å; G281-F285 PolarHBondContact O-N 3.45Å; Q282-F285 PolarHBondContact O-N 3.49Å; V283-F285 PolarHBondContact O-N 2.86Å; F285-F289 AromaticContact CD1-CD2 3.9Å; F285-F289 HydrophobicContact CD1-CD2 3.9Å; F285-F289 HydrophobicContact CD1-CE2 4.22Å; F285-F289 WeakPolarHBondContact O-CA 3.44Å; F285-F289 WeakPolarHBondContact O-CB 3.35Å; F285-F289 PolarHBondContact O-N 3.27Å; F285-F289 VanDerWaalsContact O-N 3.11Å; F285-N290 PolarHBondContact O-N 3.23Å; F285-F291 HydrophobicContact CB-CB 4.42Å; F285-F291 HydrophobicContact CB-CD2 4.25Å; F285-F291 PolarHBondContact O-N 2.78Å; F285-A296 HydrophobicContact CB-CB 3.91Å; F285-V299 HydrophobicContact CB-CG1 4.33Å; F285-V299 HydrophobicContact CD1-CG1 4.17Å; F285-V299 HydrophobicContact CD2-CG1 3.38Å; F285-V299 HydrophobicContact CE1-CG1 4.4Å; F285-V299 HydrophobicContact CE2-CG1 3.68Å; F285-V299 HydrophobicContact CG-CG1 3.7Å; F285-V299 HydrophobicContact CZ-CG1 4.19Å; F285-N300 HydrophobicContact CE2-CB 4.2Å; F285-L342 HydrophobicContact CE1-CD2 3.84Å; F285-L342 HydrophobicContact CZ-CD2 4.41Å; F285-P349 HydrophobicContact CD1-CB 3.91Å; F285-P349 HydrophobicContact CD1-CG 4.28Å; F285-P349 HydrophobicContact CE1-CB 3.64Å; F285-P349 HydrophobicContact CE1-CG 4.47Å; F285-M353 HydrophobicContact CE1-CG 4.28Å; F285-M353 HydrophobicContact CE2-CE 4.01Å; F285-M353 HydrophobicContact CE2-CG 4.41Å; F285-M353 HydrophobicContact CE2-SD 4.42Å; F285-M353 HydrophobicContact CZ-CE 3.87Å; F285-M353 HydrophobicContact CZ-CG 3.63Å; F285-M353 HydrophobicContact CZ-SD 3.68Å
286	I	94.4	Very high	93.7	Very high	38 Å²	38	33.8 Å²	33.8	20%	0.195	19%	0.185	C	C	.	.	H	α-helix	trans	-65.8	-54.3	174.5	-65.2	165.8	0	0	0	109.4	Q282 V283 N290 P293 A296	Q282-I286 HydrophobicContact CG-CD1 4.03Å; Q282-I286 VanDerWaalsContact O-CG1 3.31Å; Q282-I286 WeakPolarHBondContact O-CG1 3.28Å; Q282-I286 PolarHBondContact O-N 2.88Å; V283-I286 PolarHBondContact O-N 3.26Å; I286-N290 VanDerWaalsContact O-CA 3.23Å; I286-N290 WeakPolarHBondContact O-CA 3.32Å; I286-N290 PolarHBondContact O-N 2.83Å; I286-P293 HydrophobicContact CD1-CB 4.32Å; I286-P293 HydrophobicContact CD1-CG 4.2Å; I286-A296 HydrophobicContact CD1-CB 4.31Å; I286-A296 HydrophobicContact CG1-CB 3.76Å
287	E	92.6	Very high	93.4	Very high	127 Å²	127	35.1 Å²	35.1	59%	0.593	19%	0.189	S	C	*	.	H	α-helix	trans	-68	-43.8	-174.5	-69.2	-64.1	143.9	0	0	112.7	V283 Y411	V283-E287 HydrophobicContact CG1-CG 3.86Å; V283-E287 WeakPolarHBondContact O-CB 3.43Å; V283-E287 WeakPolarHBondContact O-CG 3.48Å; V283-E287 PolarHBondContact O-N 3.08Å; E287-Y411 HydrophobicContact CB-CD2 4.41Å; E287-Y411 HydrophobicContact CB-CE2 4.35Å; E287-Y411 HydrophobicContact CG-CE2 4.14Å
288	K	94.8	Very high	93.2	Very high	40 Å²	40	36.2 Å²	36.2	17%	0.174	20%	0.198	C	C	.	.	H	α-helix	trans	-85.6	-40.4	-174.8	-178.2	169.5	176.8	168.2	0	113.7	F284 L342 A343 T345 F346	F284-K288 HydrophobicContact CE2-CB 4.43Å; F284-K288 HydrophobicContact CE2-CD 3.88Å; F284-K288 HydrophobicContact CZ-CD 3.72Å; F284-K288 VanDerWaalsContact O-CB 3.3Å; F284-K288 WeakPolarHBondContact O-CB 3.17Å; F284-K288 PolarHBondContact O-N 3.35Å; K288-L342 WeakPolarHBondContact CE-O 3.44Å; K288-L342 PolarHBondContact NZ-O 3.42Å; K288-A343 VanDerWaalsContact NZ-C 3.34Å; K288-A343 PolarHBondContact NZ-O 3.13Å; K288-T345 WeakPolarHBondContact CE-O 3.4Å; K288-T345 PolarHBondContact NZ-O 3.12Å; K288-F346 HydrophobicContact CG-CE1 4.18Å
289	F	95.3	Very high	93.2	Very high	27 Å²	27	36.1 Å²	36.1	12%	0.118	20%	0.198	C	C	.	.	H	α-helix	trans	-108.2	2	-171	-66.6	-89.8	0	0	0	113.4	F284 F285 F291 W347 P349	F284-F289 HydrophobicContact CE1-CD2 4.33Å; F284-F289 AromaticContact CE1-CE2 3.75Å; F284-F289 HydrophobicContact CE1-CE2 3.75Å; F284-F289 HydrophobicContact CZ-CE2 4.05Å; F285-F289 AromaticContact CD1-CD2 3.9Å; F285-F289 HydrophobicContact CD1-CD2 3.9Å; F285-F289 HydrophobicContact CD1-CE2 4.22Å; F285-F289 WeakPolarHBondContact O-CA 3.44Å; F285-F289 WeakPolarHBondContact O-CB 3.35Å; F285-F289 PolarHBondContact O-N 3.27Å; F285-F289 VanDerWaalsContact O-N 3.11Å; F289-F291 HydrophobicContact CB-CD1 3.74Å; F289-F291 HydrophobicContact CB-CE1 3.89Å; F289-F291 HydrophobicContact CB-CG 4.28Å; F289-F291 WeakPolarHBondContact O-CD1 3.33Å; F289-F291 PolarHBondContact O-N 2.85Å; F289-W347 VanDerWaalsContact CE1-O 3.26Å; F289-W347 WeakPolarHBondContact CE1-O 3.42Å; F289-P349 HydrophobicContact CD1-CG 4.06Å; F289-P349 HydrophobicContact CD2-CB 4.47Å; F289-P349 HydrophobicContact CD2-CG 4.41Å; F289-P349 HydrophobicContact CE1-CB 4.33Å; F289-P349 HydrophobicContact CE1-CG 4.3Å; F289-P349 HydrophobicContact CE2-CB 4.27Å; F289-P349 HydrophobicContact CG-CG 4.11Å; F289-P349 HydrophobicContact CZ-CB 4.2Å
290	N	94.5	Very high	93.3	Very high	145 Å²	145	36.1 Å²	36.1	78%	0.775	20%	0.198	S	C	*	.			trans	54.7	33.7	-175.8	-63.2	-60.6	0	0	0	112.8	F285 I286	F285-N290 PolarHBondContact O-N 3.23Å; I286-N290 VanDerWaalsContact O-CA 3.23Å; I286-N290 WeakPolarHBondContact O-CA 3.32Å; I286-N290 PolarHBondContact O-N 2.83Å
291	F	95.3	Very high	93.4	Very high	37 Å²	37	36.2 Å²	36.2	16%	0.162	20%	0.198	C	C	.	.			trans	-73.4	144.5	176.7	-82	17.3	0	0	0	110.3	F285 F289 Q295 A296 V299 P349 W350	F285-F291 HydrophobicContact CB-CB 4.42Å; F285-F291 HydrophobicContact CB-CD2 4.25Å; F285-F291 PolarHBondContact O-N 2.78Å; F289-F291 HydrophobicContact CB-CD1 3.74Å; F289-F291 HydrophobicContact CB-CE1 3.89Å; F289-F291 HydrophobicContact CB-CG 4.28Å; F289-F291 WeakPolarHBondContact O-CD1 3.33Å; F289-F291 PolarHBondContact O-N 2.85Å; F291-Q295 HydrophobicContact CB-CB 4.02Å; F291-Q295 HydrophobicContact CD2-CB 3.9Å; F291-Q295 HydrophobicContact CG-CB 4.1Å; F291-A296 HydrophobicContact CB-CB 4.3Å; F291-V299 HydrophobicContact CD2-CG1 4.02Å; F291-V299 HydrophobicContact CE2-CB 4.31Å; F291-V299 HydrophobicContact CE2-CG1 4.02Å; F291-P349 HydrophobicContact CD2-CG 4.45Å; F291-P349 HydrophobicContact CE1-CG 4.18Å; F291-P349 HydrophobicContact CE2-CG 3.45Å; F291-P349 VanDerWaalsContact CE2-CG 3.45Å; F291-P349 HydrophobicContact CZ-CG 3.29Å; F291-W350 AromaticContact CE2-NE1 3.89Å
292	S	93.6	Very high	93.5	Very high	48 Å²	48	37.4 Å²	37.4	34%	0.336	20%	0.204	S	C	.	.			trans	-62.5	154.3	165.4	64.2	0	0	0	0	110.3	A294 Q295 A296	S292-A294 PolarHBondContact O-N 3.42Å; S292-A294 VanDerWaalsContact O-N 3.08Å; S292-Q295 PolarHBondContact O-N 3.2Å; S292-Q295 WeakPolarHBondContact OG-CB 3.38Å; S292-Q295 VanDerWaalsContact OG-CG 3.29Å; S292-Q295 WeakPolarHBondContact OG-CG 3.16Å; S292-Q295 PolarHBondContact OG-N 3.07Å; S292-Q295 PolarHBondContact OG-OE1 3.03Å; S292-A296 PolarHBondContact O-N 3.4Å
293	P	89.5	Confident	93.7	Very high	60 Å²	60	37.4 Å²	37.4	39%	0.39	20%	0.204	S	C	.	.	H	α-helix	trans	-54.2	-32.9	176.8	-28.5	35.3	0	0	0	113.7	I286 R297	I286-P293 HydrophobicContact CD1-CB 4.32Å; I286-P293 HydrophobicContact CD1-CG 4.2Å; P293-R297 WeakPolarHBondContact O-CG 3.44Å; P293-R297 PolarHBondContact O-N 3.41Å; P293-R297 VanDerWaalsContact O-N 3.09Å; P293-R297 PolarHBondContact O-NH1 3.41Å
294	A	89.3	Confident	93.7	Very high	58 Å²	58	36.4 Å²	36.4	48%	0.479	20%	0.198	S	C	.	.	H	α-helix	trans	-68.7	-44.8	175.4	0	0	0	0	0	112.3	S292 R297 A298	S292-A294 PolarHBondContact O-N 3.42Å; S292-A294 VanDerWaalsContact O-N 3.08Å; A294-R297 PolarHBondContact O-N 3.21Å; A294-A298 WeakPolarHBondContact O-CB 3.24Å; A294-A298 PolarHBondContact O-N 2.94Å
295	Q	93.2	Very high	93.7	Very high	97 Å²	97	39.6 Å²	39.6	45%	0.453	21%	0.214	S	C	.	.	H	α-helix	trans	-64.6	-41.1	175.7	-73.5	165.5	-48.8	0	0	111.7	F291 S292 A298 V299	F291-Q295 HydrophobicContact CB-CB 4.02Å; F291-Q295 HydrophobicContact CD2-CB 3.9Å; F291-Q295 HydrophobicContact CG-CB 4.1Å; S292-Q295 PolarHBondContact O-N 3.2Å; S292-Q295 WeakPolarHBondContact OG-CB 3.38Å; S292-Q295 VanDerWaalsContact OG-CG 3.29Å; S292-Q295 WeakPolarHBondContact OG-CG 3.16Å; S292-Q295 PolarHBondContact OG-N 3.07Å; S292-Q295 PolarHBondContact OG-OE1 3.03Å; Q295-A298 PolarHBondContact O-N 2.69Å; Q295-V299 WeakPolarHBondContact O-CG1 2.96Å; Q295-V299 PolarHBondContact O-N 2.93Å
296	A	93.1	Very high	93.6	Very high	0 Å²	0	41.4 Å²	41.4	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-61.4	-44.2	177.7	0	0	0	0	0	112.2	Q282 F285 I286 F291 S292 V299 N300	Q282-A296 HydrophobicContact CG-CB 4.05Å; Q282-A296 WeakPolarHBondContact O-CB 3.39Å; F285-A296 HydrophobicContact CB-CB 3.91Å; I286-A296 HydrophobicContact CD1-CB 4.31Å; I286-A296 HydrophobicContact CG1-CB 3.76Å; F291-A296 HydrophobicContact CB-CB 4.3Å; S292-A296 PolarHBondContact O-N 3.4Å; A296-V299 WeakPolarHBondContact O-CG1 3.38Å; A296-N300 VanDerWaalsContact O-CB 3.3Å; A296-N300 WeakPolarHBondContact O-CB 3.39Å; A296-N300 PolarHBondContact O-N 3.32Å
297	R	89.4	Confident	93.5	Very high	32 Å²	32	39.6 Å²	39.6	12%	0.121	21%	0.214	C	C	.	.	H	α-helix	trans	-64.3	-43.8	173.5	-74.9	-170.9	-53.4	-89.2	0.5	112.6	A59 M183 Q282 P293 A294 N300 S301	A59-R297 WeakPolarHBondContact O-CD 3.38Å; M183-R297 WeakPolarHBondContact O-CD 3.33Å; Q282-R297 HydrophobicContact CG-CG 4.19Å; P293-R297 WeakPolarHBondContact O-CG 3.44Å; P293-R297 PolarHBondContact O-N 3.41Å; P293-R297 VanDerWaalsContact O-N 3.09Å; P293-R297 PolarHBondContact O-NH1 3.41Å; A294-R297 PolarHBondContact O-N 3.21Å; R297-N300 PolarHBondContact O-N 3.24Å; R297-S301 WeakPolarHBondContact O-CB 3.41Å; R297-S301 PolarHBondContact O-N 2.91Å; R297-S301 PolarHBondContact O-OG 3.34Å
298	A	92.6	Very high	93.4	Very high	24 Å²	24	33.9 Å²	33.9	20%	0.198	19%	0.189	C	C	.	.	H	α-helix	trans	-61.8	-47.7	-179.5	0	0	0	0	0	111.4	A294 Q295 N300 S301 I302 W350	A294-A298 WeakPolarHBondContact O-CB 3.24Å; A294-A298 PolarHBondContact O-N 2.94Å; Q295-A298 PolarHBondContact O-N 2.69Å; A298-N300 PolarHBondContact O-N 2.68Å; A298-S301 PolarHBondContact O-N 2.95Å; A298-S301 PolarHBondContact O-OG 3.32Å; A298-I302 PolarHBondContact O-N 3.41Å; A298-W350 HydrophobicContact CB-CH2 3.79Å; A298-W350 HydrophobicContact CB-CZ2 4.11Å
299	V	95.4	Very high	93.3	Very high	0 Å²	0	35.4 Å²	35.4	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-68.3	-33.3	178.2	74.7	0	0	0	0	112.2	F285 F291 Q295 A296 I302 P349 W350 M353	F285-V299 HydrophobicContact CB-CG1 4.33Å; F285-V299 HydrophobicContact CD1-CG1 4.17Å; F285-V299 HydrophobicContact CD2-CG1 3.38Å; F285-V299 HydrophobicContact CE1-CG1 4.4Å; F285-V299 HydrophobicContact CE2-CG1 3.68Å; F285-V299 HydrophobicContact CG-CG1 3.7Å; F285-V299 HydrophobicContact CZ-CG1 4.19Å; F291-V299 HydrophobicContact CD2-CG1 4.02Å; F291-V299 HydrophobicContact CE2-CB 4.31Å; F291-V299 HydrophobicContact CE2-CG1 4.02Å; Q295-V299 WeakPolarHBondContact O-CG1 2.96Å; Q295-V299 PolarHBondContact O-N 2.93Å; A296-V299 WeakPolarHBondContact O-CG1 3.38Å; V299-I302 WeakPolarHBondContact O-CG2 3.46Å; V299-I302 PolarHBondContact O-N 2.85Å; V299-P349 HydrophobicContact CG2-CB 4.41Å; V299-P349 HydrophobicContact CG2-CG 4.47Å; V299-W350 HydrophobicContact CB-CD2 4.04Å; V299-W350 HydrophobicContact CB-CE3 4.38Å; V299-W350 HydrophobicContact CB-CH2 4.23Å; V299-W350 HydrophobicContact CB-CZ2 3.87Å; V299-W350 HydrophobicContact CB-CZ3 4.46Å; V299-W350 HydrophobicContact CG2-CB 4.39Å; V299-W350 HydrophobicContact CG2-CD2 3.65Å; V299-W350 HydrophobicContact CG2-CE3 4.05Å; V299-W350 HydrophobicContact CG2-CG 3.79Å; V299-W350 HydrophobicContact CG2-CZ2 4.42Å; V299-M353 HydrophobicContact CG2-CB 4.2Å; V299-M353 HydrophobicContact CG2-CG 3.99Å
300	N	94.5	Very high	93	Very high	1 Å²	1	34.8 Å²	34.8	1%	0.005	20%	0.203	C	C	.	.	H	α-helix	trans	-66.9	-39.6	173.9	-159.9	27.5	0	0	0	111.4	I278 F285 A296 R297 A298 I302	I278-N300 PolarHBondContact O-ND2 2.94Å; F285-N300 HydrophobicContact CE2-CB 4.2Å; A296-N300 VanDerWaalsContact O-CB 3.3Å; A296-N300 WeakPolarHBondContact O-CB 3.39Å; A296-N300 PolarHBondContact O-N 3.32Å; R297-N300 PolarHBondContact O-N 3.24Å; A298-N300 PolarHBondContact O-N 2.68Å; N300-I302 VanDerWaalsContact C-N 3.27Å; N300-I302 PolarHBondContact O-N 3.12Å
301	S	94.4	Very high	92.7	Very high	1 Å²	1	28.1 Å²	28.1	1%	0.007	17%	0.167	C	C	.	.	H	α-helix	trans	-69.9	-18.4	179.8	77.4	0	0	0	0	114.6	N184 R297 A298 V303 Y304 I305	N184-S301 WeakPolarHBondContact ND2-CB 3.22Å; N184-S301 PolarHBondContact ND2-OG 3.31Å; R297-S301 WeakPolarHBondContact O-CB 3.41Å; R297-S301 PolarHBondContact O-N 2.91Å; R297-S301 PolarHBondContact O-OG 3.34Å; A298-S301 PolarHBondContact O-N 2.95Å; A298-S301 PolarHBondContact O-OG 3.32Å; S301-V303 PolarHBondContact O-N 2.86Å; S301-V303 VanDerWaalsContact O-N 3.17Å; S301-Y304 PolarHBondContact O-N 3.44Å; S301-I305 WeakPolarHBondContact O-CG1 3.34Å; S301-I305 PolarHBondContact O-N 3.28Å
302	I	95.6	Very high	92.1	Very high	25 Å²	25	28.9 Å²	28.9	13%	0.128	18%	0.176	C	C	.	.	H	α-helix	trans	-61.4	-28.2	-176.8	-157	59.1	0	0	0	112.3	A298 V299 N300 Y304 I305 I306 W350 M353	A298-I302 PolarHBondContact O-N 3.41Å; V299-I302 WeakPolarHBondContact O-CG2 3.46Å; V299-I302 PolarHBondContact O-N 2.85Å; N300-I302 VanDerWaalsContact C-N 3.27Å; N300-I302 PolarHBondContact O-N 3.12Å; I302-Y304 VanDerWaalsContact C-N 3.3Å; I302-Y304 PolarHBondContact O-N 3.28Å; I302-I305 HydrophobicContact CD1-CB 4.13Å; I302-I305 HydrophobicContact CD1-CD1 4.13Å; I302-I305 HydrophobicContact CD1-CG2 4.11Å; I302-I305 PolarHBondContact O-N 2.85Å; I302-I306 HydrophobicContact CD1-CD1 4.41Å; I302-I306 HydrophobicContact CD1-CG1 4.46Å; I302-I306 HydrophobicContact CG1-CD1 3.79Å; I302-I306 HydrophobicContact CG1-CG1 4.26Å; I302-I306 WeakPolarHBondContact O-CB 3.26Å; I302-I306 WeakPolarHBondContact O-CG1 3.3Å; I302-I306 PolarHBondContact O-N 2.93Å; I302-W350 HydrophobicContact CB-CE3 4.27Å; I302-W350 HydrophobicContact CB-CZ3 4.01Å; I302-W350 HydrophobicContact CD1-CE3 4.46Å; I302-W350 HydrophobicContact CD1-CZ3 4Å; I302-W350 HydrophobicContact CG1-CE3 4.09Å; I302-W350 HydrophobicContact CG1-CZ3 3.98Å; I302-M353 HydrophobicContact CG2-CB 3.43Å; I302-M353 VanDerWaalsContact CG2-CB 3.43Å
303	V	95	Very high	91.9	Very high	0 Å²	0	31.6 Å²	31.6	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-57.6	-46.1	175.8	176.4	0	0	0	0	110.2	I278 S301 S307 M353 L356 Y360	I278-V303 HydrophobicContact CD1-CG1 4.09Å; S301-V303 PolarHBondContact O-N 2.86Å; S301-V303 VanDerWaalsContact O-N 3.17Å; V303-S307 WeakPolarHBondContact O-CB 3.32Å; V303-S307 PolarHBondContact O-N 3.24Å; V303-M353 HydrophobicContact CG2-CB 4.43Å; V303-M353 HydrophobicContact CG2-CE 3.37Å; V303-M353 HydrophobicContact CG2-SD 4.19Å; V303-L356 HydrophobicContact CG2-CB 4.32Å; V303-L356 HydrophobicContact CG2-CD2 4.09Å; V303-L356 HydrophobicContact CG2-CG 4.45Å; V303-Y360 HydrophobicContact CG1-CD1 4.46Å
304	Y	94.1	Very high	92	Very high	3 Å²	3	30.1 Å²	30.1	1%	0.012	17%	0.174	C	C	.	.	H	α-helix	trans	-76.3	-38.1	178.5	-60.8	-45	0	0	0	112.5	D55 S179 T180 I278 S301 I302 I306 S307 A308	D55-Y304 PolarHBondContact OD1-OH 3.42Å; S179-Y304 VanDerWaalsContact CB-CD2 3.45Å; T180-Y304 VanDerWaalsContact OG1-CB 3.31Å; T180-Y304 WeakPolarHBondContact OG1-CB 3.38Å; I278-Y304 HydrophobicContact CD1-CE1 3.92Å; I278-Y304 HydrophobicContact CD1-CE2 4.45Å; I278-Y304 HydrophobicContact CG2-CE2 4.01Å; S301-Y304 PolarHBondContact O-N 3.44Å; I302-Y304 VanDerWaalsContact C-N 3.3Å; I302-Y304 PolarHBondContact O-N 3.28Å; Y304-I306 VanDerWaalsContact C-N 3.32Å; Y304-I306 PolarHBondContact O-N 2.85Å; Y304-S307 PolarHBondContact O-N 3.25Å; Y304-A308 WeakPolarHBondContact O-CB 3.24Å; Y304-A308 PolarHBondContact O-N 3.3Å
305	I	95	Very high	91.8	Very high	69 Å²	69	28 Å²	28	35%	0.354	16%	0.158	S	C	.	.	H	α-helix	trans	-58.1	-45	176.6	-68.8	168.8	0	0	0	111.1	T180 S301 I302 P309	T180-I305 HydrophobicContact CG2-CD1 3.92Å; T180-I305 HydrophobicContact CG2-CG1 3.34Å; S301-I305 WeakPolarHBondContact O-CG1 3.34Å; S301-I305 PolarHBondContact O-N 3.28Å; I302-I305 HydrophobicContact CD1-CB 4.13Å; I302-I305 HydrophobicContact CD1-CD1 4.13Å; I302-I305 HydrophobicContact CD1-CG2 4.11Å; I302-I305 PolarHBondContact O-N 2.85Å; I305-P309 WeakPolarHBondContact O-CD 3.37Å
306	I	95.4	Very high	91.4	Very high	38 Å²	38	29.9 Å²	29.9	20%	0.195	17%	0.165	C	C	.	.	H	α-helix	trans	-74	-42.9	179.2	-71.6	168	0	0	0	110.7	I302 Y304 A308 P309 A310 S354 V358	I302-I306 HydrophobicContact CD1-CD1 4.41Å; I302-I306 HydrophobicContact CD1-CG1 4.46Å; I302-I306 HydrophobicContact CG1-CD1 3.79Å; I302-I306 HydrophobicContact CG1-CG1 4.26Å; I302-I306 WeakPolarHBondContact O-CB 3.26Å; I302-I306 WeakPolarHBondContact O-CG1 3.3Å; I302-I306 PolarHBondContact O-N 2.93Å; Y304-I306 VanDerWaalsContact C-N 3.32Å; Y304-I306 PolarHBondContact O-N 2.85Å; I306-A308 VanDerWaalsContact C-N 3.26Å; I306-A308 PolarHBondContact O-N 3.48Å; I306-P309 VanDerWaalsContact O-CD 3.26Å; I306-P309 WeakPolarHBondContact O-CD 3.08Å; I306-A310 HydrophobicContact CG2-CB 4.47Å; I306-A310 WeakPolarHBondContact O-CB 2.94Å; I306-A310 PolarHBondContact O-N 3.05Å; I306-S354 VanDerWaalsContact CD1-CA 3.49Å; I306-V358 HydrophobicContact CG2-CG2 3.65Å
307	S	91.8	Very high	91.2	Very high	0 Å²	0	32.8 Å²	32.8	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-61.6	-33.6	-178.9	176.6	0	0	0	0	112.7	V303 Y304 A310 S311	V303-S307 WeakPolarHBondContact O-CB 3.32Å; V303-S307 PolarHBondContact O-N 3.24Å; Y304-S307 PolarHBondContact O-N 3.25Å; S307-A310 PolarHBondContact O-N 3.07Å; S307-S311 WeakPolarHBondContact O-CB 3.4Å; S307-S311 PolarHBondContact O-N 2.96Å; S307-S311 PolarHBondContact O-OG 3.43Å
308	A	90.6	Very high	91.1	Very high	7 Å²	7	31.3 Å²	31.3	6%	0.058	18%	0.175	C	C	.	.	H	α-helix	trans	-56.1	-57.4	-178.1	0	0	0	0	0	113.5	S173 R176 Y304 I306 P312	S173-A308 PolarHBondContact OG-O 3.28Å; R176-A308 HydrophobicContact CB-CB 3.67Å; R176-A308 HydrophobicContact CG-CB 4.3Å; Y304-A308 WeakPolarHBondContact O-CB 3.24Å; Y304-A308 PolarHBondContact O-N 3.3Å; I306-A308 VanDerWaalsContact C-N 3.26Å; I306-A308 PolarHBondContact O-N 3.48Å; A308-P312 WeakPolarHBondContact O-CD 3.37Å
309	P	91.3	Very high	90.7	Very high	71 Å²	71	32.5 Å²	32.5	46%	0.461	18%	0.178	S	C	.	.	H	α-helix	trans	-80.5	-26.5	174.4	32.5	-37	0	0	0	113.5	I305 I306 S311 P312 I313	I305-P309 WeakPolarHBondContact O-CD 3.37Å; I306-P309 VanDerWaalsContact O-CD 3.26Å; I306-P309 WeakPolarHBondContact O-CD 3.08Å; P309-S311 VanDerWaalsContact C-N 3.32Å; P309-S311 PolarHBondContact O-N 2.58Å; P309-P312 WeakPolarHBondContact O-CD 3.32Å; P309-P312 WeakPolarHBondContact O-CG 3.27Å; P309-I313 WeakPolarHBondContact O-CD1 3.08Å; P309-I313 WeakPolarHBondContact O-CG1 3.3Å
310	A	90.3	Very high	90.2	Very high	15 Å²	15	39.8 Å²	39.8	12%	0.124	21%	0.209	C	C	.	.	H	α-helix	trans	-67	-34.4	-179.4	0	0	0	0	0	112.1	I306 S307 I313 L314 S361	I306-A310 HydrophobicContact CG2-CB 4.47Å; I306-A310 WeakPolarHBondContact O-CB 2.94Å; I306-A310 PolarHBondContact O-N 3.05Å; S307-A310 PolarHBondContact O-N 3.07Å; A310-I313 PolarHBondContact O-N 3.13Å; A310-L314 HydrophobicContact CB-CD1 4.02Å; A310-L314 VanDerWaalsContact O-CB 3.27Å; A310-L314 WeakPolarHBondContact O-CB 3.25Å; A310-L314 VanDerWaalsContact O-CG 3.29Å; A310-L314 WeakPolarHBondContact O-CG 3.29Å; A310-L314 PolarHBondContact O-N 3.29Å; A310-S361 VanDerWaalsContact C-OG 3.23Å
311	S	87.3	Confident	89.9	Confident	4 Å²	4	42.8 Å²	42.8	3%	0.028	23%	0.228	C	C	.	.	H	α-helix	trans	-58.9	-53.6	-175.9	-59.5	0	0	0	0	113.5	S307 P309 I313 G315 S361 C365	S307-S311 WeakPolarHBondContact O-CB 3.4Å; S307-S311 PolarHBondContact O-N 2.96Å; S307-S311 PolarHBondContact O-OG 3.43Å; P309-S311 VanDerWaalsContact C-N 3.32Å; P309-S311 PolarHBondContact O-N 2.58Å; S311-I313 VanDerWaalsContact C-N 3.31Å; S311-I313 PolarHBondContact O-N 3.4Å; S311-G315 PolarHBondContact O-N 3.25Å; S311-S361 WeakPolarHBondContact CA-OG 3.47Å; S311-S361 PolarHBondContact N-OG 3.43Å; S311-S361 PolarHBondContact OG-OG 3.38Å; S311-C365 PolarHBondContact O-SG 3.2Å
312	P	83.9	Confident	89.4	Confident	54 Å²	54	42.8 Å²	42.8	35%	0.351	23%	0.228	S	C	.	.	H	α-helix	trans	-63.7	-36.1	177.7	23.4	-33.8	0	0	0	112.9	A308 P309 F316	A308-P312 WeakPolarHBondContact O-CD 3.37Å; P309-P312 WeakPolarHBondContact O-CD 3.32Å; P309-P312 WeakPolarHBondContact O-CG 3.27Å; P312-F316 PolarHBondContact O-N 3.4Å; P312-F316 VanDerWaalsContact O-N 3.11Å
313	I	89.4	Confident	89.1	Confident	105 Å²	105	50 Å²	50	54%	0.538	25%	0.253	S	S	.	.	H	α-helix	trans	-69.3	-50.6	-179.2	-61.6	171.2	0	0	0	110.6	P309 A310 S311 F316 I317	P309-I313 WeakPolarHBondContact O-CD1 3.08Å; P309-I313 WeakPolarHBondContact O-CG1 3.3Å; A310-I313 PolarHBondContact O-N 3.13Å; S311-I313 VanDerWaalsContact C-N 3.31Å; S311-I313 PolarHBondContact O-N 3.4Å; I313-F316 PolarHBondContact O-N 2.87Å; I313-I317 HydrophobicContact CG2-CD1 4Å; I313-I317 WeakPolarHBondContact O-CG1 3.45Å; I313-I317 PolarHBondContact O-N 3.38Å
314	L	89.9	Confident	88.9	Confident	28 Å²	28	50 Å²	50	15%	0.147	25%	0.253	C	S	.	.	H	α-helix	trans	-67.7	-38.1	179.8	-67.6	174.7	0	0	0	111.1	A310 F316 I317 V318 V358 L362	A310-L314 HydrophobicContact CB-CD1 4.02Å; A310-L314 VanDerWaalsContact O-CB 3.27Å; A310-L314 WeakPolarHBondContact O-CB 3.25Å; A310-L314 VanDerWaalsContact O-CG 3.29Å; A310-L314 WeakPolarHBondContact O-CG 3.29Å; A310-L314 PolarHBondContact O-N 3.29Å; L314-F316 VanDerWaalsContact C-N 3.35Å; L314-F316 PolarHBondContact O-N 2.7Å; L314-I317 HydrophobicContact CD2-CD1 4.42Å; L314-I317 PolarHBondContact O-N 3.36Å; L314-V318 WeakPolarHBondContact O-CB 3.42Å; L314-V318 WeakPolarHBondContact O-CG2 3.5Å; L314-V318 PolarHBondContact O-N 3.33Å; L314-V358 HydrophobicContact CD1-CG1 4.38Å; L314-L362 HydrophobicContact CB-CD1 4.47Å; L314-L362 HydrophobicContact CD1-CB 4.07Å; L314-L362 HydrophobicContact CD1-CD1 4.49Å; L314-L362 HydrophobicContact CD2-CD1 4.39Å
315	G	85.6	Confident	88.9	Confident	14 Å²	14	50 Å²	50	14%	0.144	25%	0.253	C	S	.	.	H	α-helix	trans	-55.8	-48.5	171.8	0	0	0	0	0	112.1	S311 I317 V318 D319	S311-G315 PolarHBondContact O-N 3.25Å; G315-I317 VanDerWaalsContact C-N 3.34Å; G315-I317 PolarHBondContact O-N 2.83Å; G315-V318 PolarHBondContact O-N 3.4Å; G315-D319 WeakPolarHBondContact O-CB 3.43Å; G315-D319 VanDerWaalsContact O-CG 3.3Å; G315-D319 PolarHBondContact O-N 3.12Å
316	F	84.9	Confident	89	Confident	136 Å²	136	48.5 Å²	48.5	60%	0.596	26%	0.255	S	S	*	.	H	α-helix	trans	-61.2	-40.4	175.7	178.9	-98.6	0	0	0	113	P312 I313 L314 K320	P312-F316 PolarHBondContact O-N 3.4Å; P312-F316 VanDerWaalsContact O-N 3.11Å; I313-F316 PolarHBondContact O-N 2.87Å; L314-F316 VanDerWaalsContact C-N 3.35Å; L314-F316 PolarHBondContact O-N 2.7Å; F316-K320 HydrophobicContact CE1-CD 4.15Å; F316-K320 HydrophobicContact CZ-CD 4.26Å; F316-K320 VanDerWaalsContact O-CB 3.27Å; F316-K320 WeakPolarHBondContact O-CB 3.43Å; F316-K320 PolarHBondContact O-N 3.47Å
317	I	89.6	Confident	89	Confident	62 Å²	62	50.3 Å²	50.3	32%	0.318	26%	0.259	S	S	.	.	H	α-helix	trans	-65.5	-46.1	177.9	-68.5	166	0	0	0	110.8	I313 L314 G315 K320 T321 W327	I313-I317 HydrophobicContact CG2-CD1 4Å; I313-I317 WeakPolarHBondContact O-CG1 3.45Å; I313-I317 PolarHBondContact O-N 3.38Å; L314-I317 HydrophobicContact CD2-CD1 4.42Å; L314-I317 PolarHBondContact O-N 3.36Å; G315-I317 VanDerWaalsContact C-N 3.34Å; G315-I317 PolarHBondContact O-N 2.83Å; I317-K320 PolarHBondContact O-N 3.18Å; I317-T321 HydrophobicContact CG2-CG2 4.21Å; I317-T321 WeakPolarHBondContact O-CB 3.39Å; I317-T321 WeakPolarHBondContact O-CG2 3.46Å; I317-T321 PolarHBondContact O-N 3.35Å; I317-T321 PolarHBondContact O-OG1 3.42Å; I317-W327 HydrophobicContact CG2-CH2 4.01Å; I317-W327 HydrophobicContact CG2-CZ2 3.69Å
318	V	87.7	Confident	89.3	Confident	0 Å²	0	50.3 Å²	50.3	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-61.3	-48.6	178.4	170.9	0	0	0	0	110.3	L314 G315 K320 T321 G322 N324 W327 L362 A366	L314-V318 WeakPolarHBondContact O-CB 3.42Å; L314-V318 WeakPolarHBondContact O-CG2 3.5Å; L314-V318 PolarHBondContact O-N 3.33Å; G315-V318 PolarHBondContact O-N 3.4Å; V318-K320 VanDerWaalsContact C-N 3.29Å; V318-K320 PolarHBondContact O-N 3.21Å; V318-T321 PolarHBondContact O-N 3.32Å; V318-G322 WeakPolarHBondContact O-CA 2.84Å; V318-G322 PolarHBondContact O-N 2.87Å; V318-N324 WeakPolarHBondContact CG1-OD1 3.37Å; V318-W327 HydrophobicContact CG2-CB 4.22Å; V318-W327 HydrophobicContact CG2-CD2 4.19Å; V318-W327 HydrophobicContact CG2-CG 3.81Å; V318-L362 HydrophobicContact CG2-CD1 4.01Å; V318-A366 HydrophobicContact CG1-CB 4.06Å; V318-A366 HydrophobicContact CG2-CB 4.33Å
319	D	84.1	Confident	89.7	Confident	50 Å²	50	53.9 Å²	53.9	27%	0.267	27%	0.274	S	S	.	.	H	α-helix	trans	-57.7	-42.3	177.9	-75.9	-13.4	0	0	0	112.2	G315 A447	G315-D319 WeakPolarHBondContact O-CB 3.43Å; G315-D319 VanDerWaalsContact O-CG 3.3Å; G315-D319 PolarHBondContact O-N 3.12Å; D319-A447 WeakPolarHBondContact O-CB 3.49Å; D319-A447 PolarHBondContact O-N 3.47Å; D319-A447 VanDerWaalsContact O-N 3.07Å
320	K	84.4	Confident	90	Very high	153 Å²	153	52.5 Å²	52.5	67%	0.665	27%	0.269	S	S	*	.	H	α-helix	trans	-75.1	-41	-177.7	-173.4	176	-179.2	179.4	0	112.9	F316 I317 V318	F316-K320 HydrophobicContact CE1-CD 4.15Å; F316-K320 HydrophobicContact CZ-CD 4.26Å; F316-K320 VanDerWaalsContact O-CB 3.27Å; F316-K320 WeakPolarHBondContact O-CB 3.43Å; F316-K320 PolarHBondContact O-N 3.47Å; I317-K320 PolarHBondContact O-N 3.18Å; V318-K320 VanDerWaalsContact C-N 3.29Å; V318-K320 PolarHBondContact O-N 3.21Å
321	T	87.9	Confident	90.4	Very high	64 Å²	64	51.8 Å²	51.8	39%	0.393	26%	0.263	S	S	.	.	H	α-helix	trans	-85.5	-19.7	-176.2	56.3	0	0	0	0	113	I317 V318 W327	I317-T321 HydrophobicContact CG2-CG2 4.21Å; I317-T321 WeakPolarHBondContact O-CB 3.39Å; I317-T321 WeakPolarHBondContact O-CG2 3.46Å; I317-T321 PolarHBondContact O-N 3.35Å; I317-T321 PolarHBondContact O-OG1 3.42Å; V318-T321 PolarHBondContact O-N 3.32Å; T321-W327 HydrophobicContact CG2-CZ2 4.49Å; T321-W327 PolarHBondContact OG1-NE1 3.33Å
322	G	83.4	Confident	90.9	Very high	0 Å²	0	51.6 Å²	51.6	0%	0	26%	0.261	C	S	.	.			trans	63.4	-142	-166.2	0	0	0	0	0	110.6	V318 N324 W327 Q445	V318-G322 WeakPolarHBondContact O-CA 2.84Å; V318-G322 PolarHBondContact O-N 2.87Å; G322-N324 VanDerWaalsContact C-N 3.32Å; G322-N324 PolarHBondContact O-N 2.96Å; G322-W327 PolarHBondContact O-NE1 3.26Å; G322-W327 VanDerWaalsContact O-NE1 3.1Å; G322-Q445 WeakPolarHBondContact CA-O 3.39Å
323	R	90.1	Very high	91.6	Very high	178 Å²	178	52.1 Å²	52.1	67%	0.672	26%	0.26	S	S	*	.			trans	57.7	40.8	177.5	-55.1	178.9	177.5	-172.9	-2	113.5	I325 G326 W327 N444	R323-I325 PolarHBondContact O-N 2.75Å; R323-I325 VanDerWaalsContact O-N 3.16Å; R323-G326 WeakPolarHBondContact O-CA 3.36Å; R323-G326 PolarHBondContact O-N 2.86Å; R323-W327 PolarHBondContact O-N 3.49Å; R323-W327 VanDerWaalsContact O-N 3.07Å; R323-N444 VanDerWaalsContact C-OD1 3.24Å; R323-N444 VanDerWaalsContact CA-OD1 3.25Å; R323-N444 WeakPolarHBondContact CA-OD1 3.34Å; R323-N444 PolarHBondContact N-O 3.01Å
324	N	89.7	Confident	92	Very high	0 Å²	0	48 Å²	48	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-51.4	-42.4	-175.2	-64.8	-61.3	0	0	0	112.5	V318 G322 G326 W327 V328 M370 F373 L443 N444	V318-N324 WeakPolarHBondContact CG1-OD1 3.37Å; G322-N324 VanDerWaalsContact C-N 3.32Å; G322-N324 PolarHBondContact O-N 2.96Å; N324-G326 VanDerWaalsContact C-N 3.33Å; N324-G326 PolarHBondContact O-N 2.97Å; N324-W327 PolarHBondContact O-N 2.82Å; N324-V328 WeakPolarHBondContact O-CG2 3.38Å; N324-V328 PolarHBondContact O-N 3.06Å; N324-M370 HydrophobicContact CB-CE 4.48Å; N324-M370 HydrophobicContact CB-CG 3.73Å; N324-M370 HydrophobicContact CB-SD 3.6Å; N324-F373 WeakPolarHBondContact ND2-CE2 3.38Å; N324-L443 PolarHBondContact ND2-O 3.22Å; N324-N444 PolarHBondContact N-OD1 2.94Å
325	I	95.3	Very high	92.4	Very high	2 Å²	2	46.7 Å²	46.7	1%	0.01	24%	0.236	C	C	.	.	H	α-helix	trans	-63.5	-40.2	178.5	-54.2	-179	0	0	0	111	R323 V328 F329 M370 V429 L432 Y433 D436 L443 N444	R323-I325 PolarHBondContact O-N 2.75Å; R323-I325 VanDerWaalsContact O-N 3.16Å; I325-V328 PolarHBondContact O-N 3.41Å; I325-F329 WeakPolarHBondContact O-CB 3.47Å; I325-F329 PolarHBondContact O-N 3.34Å; I325-M370 HydrophobicContact CG1-SD 4.1Å; I325-V429 HydrophobicContact CG2-CG1 3.99Å; I325-L432 HydrophobicContact CD1-CD2 4.4Å; I325-L432 HydrophobicContact CD1-CG 3.97Å; I325-L432 HydrophobicContact CG1-CD2 4.24Å; I325-L432 HydrophobicContact CG1-CG 4.35Å; I325-Y433 HydrophobicContact CG2-CD2 4.27Å; I325-D436 HydrophobicContact CD1-CB 3.52Å; I325-L443 HydrophobicContact CD1-CB 3.89Å; I325-L443 HydrophobicContact CD1-CD1 3.96Å; I325-L443 HydrophobicContact CG1-CB 4.06Å; I325-L443 HydrophobicContact CG1-CD1 4.44Å; I325-N444 WeakPolarHBondContact CB-OD1 3.33Å; I325-N444 PolarHBondContact N-OD1 3.27Å
326	G	96.2	Very high	93.1	Very high	38 Å²	38	47.2 Å²	47.2	39%	0.392	24%	0.235	S	C	.	.	H	α-helix	trans	-63.4	-39.9	176.6	0	0	0	0	0	113	R323 N324 F329 A330	R323-G326 WeakPolarHBondContact O-CA 3.36Å; R323-G326 PolarHBondContact O-N 2.86Å; N324-G326 VanDerWaalsContact C-N 3.33Å; N324-G326 PolarHBondContact O-N 2.97Å; G326-F329 PolarHBondContact O-N 3.18Å; G326-A330 WeakPolarHBondContact O-CB 3.41Å; G326-A330 PolarHBondContact O-N 3.34Å
327	W	96.4	Very high	93.7	Very high	75 Å²	75	43.3 Å²	43.3	28%	0.284	22%	0.224	S	C	.	.	H	α-helix	trans	-67.9	-41.4	174.9	-70.4	118.8	0	0	0	112.6	I317 V318 T321 G322 R323 N324 F329 A330 A331 L362 A366	I317-W327 HydrophobicContact CG2-CH2 4.01Å; I317-W327 HydrophobicContact CG2-CZ2 3.69Å; V318-W327 HydrophobicContact CG2-CB 4.22Å; V318-W327 HydrophobicContact CG2-CD2 4.19Å; V318-W327 HydrophobicContact CG2-CG 3.81Å; T321-W327 HydrophobicContact CG2-CZ2 4.49Å; T321-W327 PolarHBondContact OG1-NE1 3.33Å; G322-W327 PolarHBondContact O-NE1 3.26Å; G322-W327 VanDerWaalsContact O-NE1 3.1Å; R323-W327 PolarHBondContact O-N 3.49Å; R323-W327 VanDerWaalsContact O-N 3.07Å; N324-W327 PolarHBondContact O-N 2.82Å; W327-F329 VanDerWaalsContact C-N 3.34Å; W327-A330 PolarHBondContact O-N 3.17Å; W327-A331 WeakPolarHBondContact O-CB 3.45Å; W327-A331 PolarHBondContact O-N 3.43Å; W327-L362 HydrophobicContact CB-CD1 4.07Å; W327-L362 HydrophobicContact CB-CG 4.42Å; W327-L362 HydrophobicContact CD2-CD1 4.08Å; W327-L362 HydrophobicContact CE3-CD1 3.67Å; W327-L362 HydrophobicContact CE3-CD2 3.98Å; W327-L362 HydrophobicContact CE3-CG 4.38Å; W327-L362 HydrophobicContact CG-CD1 4.3Å; W327-L362 HydrophobicContact CZ3-CD1 4.4Å; W327-A366 HydrophobicContact CB-CB 3.8Å
328	V	97.6	Very high	94.1	Very high	1 Å²	1	40.4 Å²	40.4	1%	0.006	21%	0.209	C	C	.	.	H	α-helix	trans	-61.6	-44	173	173.4	0	0	0	0	110.6	I266 N324 I325 A330 A331 V332 L363 A366 L367 M370 V429	I266-V328 HydrophobicContact CG2-CG1 3.88Å; N324-V328 WeakPolarHBondContact O-CG2 3.38Å; N324-V328 PolarHBondContact O-N 3.06Å; I325-V328 PolarHBondContact O-N 3.41Å; V328-A330 PolarHBondContact O-N 2.95Å; V328-A331 PolarHBondContact O-N 3.33Å; V328-V332 HydrophobicContact CG1-CG2 4.33Å; V328-V332 VanDerWaalsContact O-CG2 3.31Å; V328-V332 WeakPolarHBondContact O-CG2 3.37Å; V328-V332 PolarHBondContact O-N 3.22Å; V328-L363 HydrophobicContact CG1-CD1 3.93Å; V328-A366 HydrophobicContact CG2-CB 3.69Å; V328-L367 HydrophobicContact CG1-CD1 4.36Å; V328-L367 HydrophobicContact CG2-CB 4.08Å; V328-L367 HydrophobicContact CG2-CD1 4.28Å; V328-M370 HydrophobicContact CG2-CE 3.62Å; V328-V429 HydrophobicContact CG1-CG1 4.27Å; V328-V429 HydrophobicContact CG1-CG2 3.54Å
329	F	98.1	Very high	94.6	Very high	82 Å²	82	40.4 Å²	40.4	36%	0.36	21%	0.209	S	C	.	.	H	α-helix	trans	-58.7	-47.1	176.2	-175.4	-100.1	0	0	0	112	I325 G326 W327 A331 V332 I333 L426 V429 V430	I325-F329 WeakPolarHBondContact O-CB 3.47Å; I325-F329 PolarHBondContact O-N 3.34Å; G326-F329 PolarHBondContact O-N 3.18Å; W327-F329 VanDerWaalsContact C-N 3.34Å; F329-A331 VanDerWaalsContact C-N 3.34Å; F329-A331 PolarHBondContact O-N 3.4Å; F329-V332 PolarHBondContact O-N 3.23Å; F329-I333 HydrophobicContact CD1-CD1 3.75Å; F329-I333 HydrophobicContact CE1-CD1 3.2Å; F329-I333 HydrophobicContact CE1-CG1 4.34Å; F329-I333 HydrophobicContact CE2-CD1 4.19Å; F329-I333 HydrophobicContact CG-CD1 4.46Å; F329-I333 HydrophobicContact CZ-CD1 3.46Å; F329-I333 VanDerWaalsContact CZ-CD1 3.46Å; F329-I333 HydrophobicContact CZ-CG1 4.44Å; F329-I333 WeakPolarHBondContact O-CG1 3.49Å; F329-I333 PolarHBondContact O-N 2.94Å; F329-L426 HydrophobicContact CD2-CD1 3.73Å; F329-L426 HydrophobicContact CE2-CD1 3.49Å; F329-L426 VanDerWaalsContact CE2-CD1 3.49Å; F329-L426 HydrophobicContact CZ-CD1 4.31Å; F329-V429 HydrophobicContact CB-CG1 3.73Å; F329-V429 HydrophobicContact CD2-CG1 3.97Å; F329-V429 HydrophobicContact CG-CG1 4.37Å; F329-V430 HydrophobicContact CD2-CG2 4.31Å; F329-V430 HydrophobicContact CE2-CG2 3.78Å
330	A	98.2	Very high	95.2	Very high	42 Å²	42	42.2 Å²	42.2	35%	0.347	22%	0.217	S	C	.	.	H	α-helix	trans	-61.2	-41.8	176.1	0	0	0	0	0	112.2	G326 W327 V328 A334 L362	G326-A330 WeakPolarHBondContact O-CB 3.41Å; G326-A330 PolarHBondContact O-N 3.34Å; W327-A330 PolarHBondContact O-N 3.17Å; V328-A330 PolarHBondContact O-N 2.95Å; A330-A334 VanDerWaalsContact O-CB 3.29Å; A330-A334 WeakPolarHBondContact O-CB 3.42Å; A330-A334 PolarHBondContact O-N 3.37Å; A330-L362 HydrophobicContact CB-CD2 4.31Å
331	A	98.1	Very high	95.8	Very high	0 Å²	0	36.4 Å²	36.4	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-62.7	-47.3	176.6	0	0	0	0	0	111.9	W327 V328 F329 I333 A334 T335 S359 L362 L363	W327-A331 WeakPolarHBondContact O-CB 3.45Å; W327-A331 PolarHBondContact O-N 3.43Å; V328-A331 PolarHBondContact O-N 3.33Å; F329-A331 VanDerWaalsContact C-N 3.34Å; F329-A331 PolarHBondContact O-N 3.4Å; A331-I333 PolarHBondContact O-N 3.41Å; A331-A334 PolarHBondContact O-N 3.05Å; A331-T335 WeakPolarHBondContact O-CB 3.3Å; A331-T335 PolarHBondContact O-N 2.88Å; A331-T335 PolarHBondContact O-OG1 2.93Å; A331-S359 WeakPolarHBondContact O-CB 3.46Å; A331-L362 HydrophobicContact CB-CB 4.06Å; A331-L362 HydrophobicContact CB-CD2 3.98Å; A331-L362 HydrophobicContact CB-CG 4.02Å; A331-L363 HydrophobicContact CB-CB 3.83Å; A331-L363 HydrophobicContact CB-CD1 4.25Å
332	V	98.6	Very high	96.3	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-62.4	-42.7	179.4	174.4	0	0	0	0	111.4	Y270 V328 F329 T335 L336 L363 I422 A425 L426 V429	Y270-V332 HydrophobicContact CD2-CG2 4Å; Y270-V332 HydrophobicContact CE2-CG2 4.35Å; V328-V332 HydrophobicContact CG1-CG2 4.33Å; V328-V332 VanDerWaalsContact O-CG2 3.31Å; V328-V332 WeakPolarHBondContact O-CG2 3.37Å; V328-V332 PolarHBondContact O-N 3.22Å; F329-V332 PolarHBondContact O-N 3.23Å; V332-T335 PolarHBondContact O-N 3.37Å; V332-L336 WeakPolarHBondContact O-CB 3.31Å; V332-L336 PolarHBondContact O-N 3.47Å; V332-L363 HydrophobicContact CG2-CD1 3.85Å; V332-I422 HydrophobicContact CG1-CG2 3.84Å; V332-I422 WeakPolarHBondContact O-CG2 3.21Å; V332-A425 HydrophobicContact CG1-CB 4.28Å; V332-L426 HydrophobicContact CG1-CB 3.76Å; V332-L426 HydrophobicContact CG1-CD1 4.04Å; V332-L426 HydrophobicContact CG1-CG 4.49Å; V332-V429 HydrophobicContact CG2-CG2 3.98Å
333	I	98.6	Very high	96.9	Very high	64 Å²	64	33.6 Å²	33.6	33%	0.328	18%	0.176	S	C	.	.	H	α-helix	trans	-63.5	-46.1	174.6	-71.3	179.7	0	0	0	111.3	F329 A331 T335 L336 C337 L426	F329-I333 HydrophobicContact CD1-CD1 3.75Å; F329-I333 HydrophobicContact CE1-CD1 3.2Å; F329-I333 HydrophobicContact CE1-CG1 4.34Å; F329-I333 HydrophobicContact CE2-CD1 4.19Å; F329-I333 HydrophobicContact CG-CD1 4.46Å; F329-I333 HydrophobicContact CZ-CD1 3.46Å; F329-I333 VanDerWaalsContact CZ-CD1 3.46Å; F329-I333 HydrophobicContact CZ-CG1 4.44Å; F329-I333 WeakPolarHBondContact O-CG1 3.49Å; F329-I333 PolarHBondContact O-N 2.94Å; A331-I333 PolarHBondContact O-N 3.41Å; I333-T335 VanDerWaalsContact C-N 3.29Å; I333-T335 PolarHBondContact O-N 2.89Å; I333-L336 WeakPolarHBondContact O-CB 3.44Å; I333-L336 PolarHBondContact O-N 3.07Å; I333-C337 PolarHBondContact O-N 3.17Å; I333-C337 PolarHBondContact O-SG 3.22Å; I333-C337 VanDerWaalsContact O-SG 3.33Å; I333-L426 HydrophobicContact CG1-CD1 3.99Å
334	A	98.4	Very high	97.2	Very high	20 Å²	20	31.2 Å²	31.2	17%	0.165	17%	0.17	C	C	.	.	H	α-helix	trans	-59.9	-41.1	178.9	0	0	0	0	0	111.7	A330 A331 C337 A338 L355	A330-A334 VanDerWaalsContact O-CB 3.29Å; A330-A334 WeakPolarHBondContact O-CB 3.42Å; A330-A334 PolarHBondContact O-N 3.37Å; A331-A334 PolarHBondContact O-N 3.05Å; A334-C337 PolarHBondContact O-N 3.32Å; A334-A338 PolarHBondContact O-N 3.06Å; A334-L355 HydrophobicContact CB-CD1 3.82Å; A334-L355 HydrophobicContact CB-CG 4.14Å; A334-L355 VanDerWaalsContact O-CD2 3.3Å; A334-L355 WeakPolarHBondContact O-CD2 3.44Å
335	T	98.4	Very high	97.4	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-65.1	-42	174.1	-58.5	0	0	0	0	112.2	Y270 I274 A331 V332 I333 C337 A338 H339 L356 S359 I422	Y270-T335 HydrophobicContact CE2-CG2 3.87Å; Y270-T335 WeakPolarHBondContact CE2-OG1 3.49Å; Y270-T335 VanDerWaalsContact CZ-OG1 3.28Å; Y270-T335 PolarHBondContact OH-OG1 3.05Å; I274-T335 HydrophobicContact CD1-CG2 3.8Å; A331-T335 WeakPolarHBondContact O-CB 3.3Å; A331-T335 PolarHBondContact O-N 2.88Å; A331-T335 PolarHBondContact O-OG1 2.93Å; V332-T335 PolarHBondContact O-N 3.37Å; I333-T335 VanDerWaalsContact C-N 3.29Å; I333-T335 PolarHBondContact O-N 2.89Å; T335-C337 PolarHBondContact O-N 3.22Å; T335-A338 WeakPolarHBondContact O-CB 3.31Å; T335-A338 PolarHBondContact O-N 2.98Å; T335-H339 PolarHBondContact O-CD2 3.41Å; T335-H339 PolarHBondContact O-N 3.06Å; T335-L356 HydrophobicContact CG2-CD1 3.77Å; T335-S359 VanDerWaalsContact OG1-CB 3.24Å; T335-S359 WeakPolarHBondContact OG1-CB 3.06Å; T335-S359 PolarHBondContact OG1-OG 3.31Å; T335-I422 HydrophobicContact CG2-CD1 3.78Å; T335-I422 HydrophobicContact CG2-CG1 4.02Å
336	L	98.6	Very high	97.3	Very high	24 Å²	24	40.4 Å²	40.4	13%	0.126	21%	0.214	C	C	.	.	H	α-helix	trans	-60.4	-46.7	175.1	-175.2	57.7	0	0	0	111	V332 I333 A338 H339 M340 C419 I422	V332-L336 WeakPolarHBondContact O-CB 3.31Å; V332-L336 PolarHBondContact O-N 3.47Å; I333-L336 WeakPolarHBondContact O-CB 3.44Å; I333-L336 PolarHBondContact O-N 3.07Å; L336-A338 VanDerWaalsContact C-N 3.32Å; L336-A338 PolarHBondContact O-N 3.42Å; L336-H339 PolarHBondContact O-N 3.17Å; L336-M340 HydrophobicContact CD1-CG 4.31Å; L336-M340 HydrophobicContact CD1-SD 4.39Å; L336-M340 HydrophobicContact CG-CG 4.4Å; L336-M340 HydrophobicContact CG-SD 4.04Å; L336-M340 WeakPolarHBondContact O-CB 3.26Å; L336-M340 VanDerWaalsContact O-CG 3.28Å; L336-M340 WeakPolarHBondContact O-CG 3.42Å; L336-M340 PolarHBondContact O-N 3.11Å; L336-C419 HydrophobicContact CD1-CB 3.97Å; L336-I422 HydrophobicContact CB-CG2 3.65Å; L336-I422 HydrophobicContact CD1-CB 4.26Å; L336-I422 HydrophobicContact CD1-CG2 4.1Å; L336-I422 HydrophobicContact CG-CG2 4.37Å
337	C	98.3	Very high	97.1	Very high	55 Å²	55	46.3 Å²	46.3	37%	0.372	22%	0.224	S	C	.	.	H	α-helix	trans	-58.5	-43.8	175.4	-70.8	0	0	0	0	111.5	I333 A334 T335 M340 M341 L355	I333-C337 PolarHBondContact O-N 3.17Å; I333-C337 PolarHBondContact O-SG 3.22Å; I333-C337 VanDerWaalsContact O-SG 3.33Å; A334-C337 PolarHBondContact O-N 3.32Å; T335-C337 PolarHBondContact O-N 3.22Å; C337-M340 PolarHBondContact O-N 3.08Å; C337-M341 WeakPolarHBondContact O-CB 3.38Å; C337-M341 WeakPolarHBondContact O-CG 3.34Å; C337-M341 PolarHBondContact O-N 2.65Å; C337-L355 HydrophobicContact CB-CD2 4.01Å
338	A	98.3	Very high	96.9	Very high	0 Å²	0	46.9 Å²	46.9	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-59.3	-49.4	177.1	0	0	0	0	0	111.8	A334 T335 L336 M341 L342 A352 L355 L356	A334-A338 PolarHBondContact O-N 3.06Å; T335-A338 WeakPolarHBondContact O-CB 3.31Å; T335-A338 PolarHBondContact O-N 2.98Å; L336-A338 VanDerWaalsContact C-N 3.32Å; L336-A338 PolarHBondContact O-N 3.42Å; A338-M341 WeakPolarHBondContact O-CB 3.22Å; A338-M341 PolarHBondContact O-N 2.96Å; A338-L342 VanDerWaalsContact O-CG 3.25Å; A338-L342 WeakPolarHBondContact O-CG 3.26Å; A338-L342 PolarHBondContact O-N 2.92Å; A338-A352 HydrophobicContact CB-CB 4.47Å; A338-A352 WeakPolarHBondContact CB-O 3.3Å; A338-L355 HydrophobicContact CB-CB 4.43Å; A338-L355 HydrophobicContact CB-CD2 4.3Å; A338-L355 HydrophobicContact CB-CG 4.44Å; A338-L356 HydrophobicContact CB-CB 4.21Å; A338-L356 HydrophobicContact CB-CD1 4.12Å
339	H	98.1	Very high	96.8	Very high	0 Å²	0	47 Å²	47	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-65.5	-38.6	176.4	-80.3	-69.4	0	0	0	112.7	A273 F277 T335 L336 M341 L342 A343 E415 F418	A273-H339 PolarHBondContact O-NE2 2.97Å; F277-H339 AromaticContact CG-CE1 3.89Å; T335-H339 PolarHBondContact O-CD2 3.41Å; T335-H339 PolarHBondContact O-N 3.06Å; L336-H339 PolarHBondContact O-N 3.17Å; H339-M341 VanDerWaalsContact C-N 3.34Å; H339-M341 PolarHBondContact O-N 2.97Å; H339-L342 CarbonylContact O-C 3.53Å; H339-L342 PolarHBondContact O-N 3.3Å; H339-A343 VanDerWaalsContact O-CB 3.23Å; H339-A343 WeakPolarHBondContact O-CB 3.02Å; H339-A343 PolarHBondContact O-N 3.33Å; H339-E415 IonicContact CE1-OE2 2.66Å; H339-E415 IonicContact CG-OE2 2.83Å; H339-E415 IonicContact ND1-OE1 2.69Å; H339-E415 IonicContact ND1-OE2 3.89Å; H339-E415 PolarHBondContact ND1-OE2 2.7Å; H339-F418 AromaticContact CE1-CD2 3.83Å
340	M	97.6	Very high	96.7	Very high	88 Å²	88	47.4 Å²	47.4	43%	0.433	23%	0.233	S	C	.	.	H	α-helix	trans	-63.5	-39.9	175	-72.9	-179.3	70.8	0	0	112.1	L336 C337 A343 F344	L336-M340 HydrophobicContact CD1-CG 4.31Å; L336-M340 HydrophobicContact CD1-SD 4.39Å; L336-M340 HydrophobicContact CG-CG 4.4Å; L336-M340 HydrophobicContact CG-SD 4.04Å; L336-M340 WeakPolarHBondContact O-CB 3.26Å; L336-M340 VanDerWaalsContact O-CG 3.28Å; L336-M340 WeakPolarHBondContact O-CG 3.42Å; L336-M340 PolarHBondContact O-N 3.11Å; C337-M340 PolarHBondContact O-N 3.08Å; M340-A343 PolarHBondContact O-N 3.01Å; M340-F344 HydrophobicContact CB-CD2 4.31Å; M340-F344 HydrophobicContact CG-CE2 4.46Å; M340-F344 WeakPolarHBondContact O-CD2 3.49Å; M340-F344 PolarHBondContact O-N 3.23Å
341	M	97	Very high	96.7	Very high	32 Å²	32	49.9 Å²	49.9	16%	0.158	24%	0.239	C	C	.	.	H	α-helix	trans	-61.3	-47	173.1	-70.8	168.5	65.2	0	0	110.5	C337 A338 H339 A343 T345 W347 I351 A352 L355	C337-M341 WeakPolarHBondContact O-CB 3.38Å; C337-M341 WeakPolarHBondContact O-CG 3.34Å; C337-M341 PolarHBondContact O-N 2.65Å; A338-M341 WeakPolarHBondContact O-CB 3.22Å; A338-M341 PolarHBondContact O-N 2.96Å; H339-M341 VanDerWaalsContact C-N 3.34Å; H339-M341 PolarHBondContact O-N 2.97Å; M341-A343 VanDerWaalsContact C-N 3.33Å; M341-A343 PolarHBondContact O-N 3.46Å; M341-T345 WeakPolarHBondContact O-CB 3.46Å; M341-T345 PolarHBondContact O-N 3.11Å; M341-T345 PolarHBondContact O-OG1 3.3Å; M341-W347 HydrophobicContact CE-CE3 3.72Å; M341-W347 HydrophobicContact CE-CZ3 4.21Å; M341-I351 HydrophobicContact CE-CB 4.06Å; M341-I351 HydrophobicContact CE-CG2 3.68Å; M341-A352 HydrophobicContact CB-CB 4.04Å; M341-A352 HydrophobicContact CE-CB 4.16Å; M341-L355 HydrophobicContact SD-CD2 4.49Å
342	L	96.8	Very high	96.6	Very high	1 Å²	1	50 Å²	50	1%	0.005	24%	0.24	C	C	.	.	H	α-helix	trans	-66.1	-32.1	177.7	-67.8	167.9	0	0	0	112.7	F277 F284 F285 K288 A338 H339 P349 A352 M353	F277-L342 HydrophobicContact CE1-CD1 4.1Å; F277-L342 HydrophobicContact CE2-CD1 4.16Å; F277-L342 HydrophobicContact CZ-CD1 3.57Å; F284-L342 HydrophobicContact CE1-CB 4.37Å; F284-L342 HydrophobicContact CE1-CD2 4.03Å; F284-L342 HydrophobicContact CZ-CB 4.15Å; F285-L342 HydrophobicContact CE1-CD2 3.84Å; F285-L342 HydrophobicContact CZ-CD2 4.41Å; K288-L342 WeakPolarHBondContact CE-O 3.44Å; K288-L342 PolarHBondContact NZ-O 3.42Å; A338-L342 VanDerWaalsContact O-CG 3.25Å; A338-L342 WeakPolarHBondContact O-CG 3.26Å; A338-L342 PolarHBondContact O-N 2.92Å; H339-L342 CarbonylContact O-C 3.53Å; H339-L342 PolarHBondContact O-N 3.3Å; L342-P349 HydrophobicContact CD2-CB 4.23Å; L342-A352 HydrophobicContact CD1-CB 4.27Å; L342-A352 HydrophobicContact CD2-CB 3.8Å; L342-A352 HydrophobicContact CG-CB 3.68Å; L342-M353 HydrophobicContact CD1-SD 4.21Å
343	A	96.1	Very high	96.6	Very high	4 Å²	4	50 Å²	50	3%	0.033	24%	0.24	C	C	.	.	H	α-helix	trans	-77.9	-52.9	-179.1	0	0	0	0	0	112.3	K288 H339 M340 M341 L412 E415	K288-A343 VanDerWaalsContact NZ-C 3.34Å; K288-A343 PolarHBondContact NZ-O 3.13Å; H339-A343 VanDerWaalsContact O-CB 3.23Å; H339-A343 WeakPolarHBondContact O-CB 3.02Å; H339-A343 PolarHBondContact O-N 3.33Å; M340-A343 PolarHBondContact O-N 3.01Å; M341-A343 VanDerWaalsContact C-N 3.33Å; M341-A343 PolarHBondContact O-N 3.46Å; A343-L412 HydrophobicContact CB-CD1 4.45Å; A343-L412 VanDerWaalsContact O-CD1 3.25Å; A343-L412 WeakPolarHBondContact O-CD1 3.27Å; A343-E415 HydrophobicContact CB-CB 3.57Å; A343-E415 HydrophobicContact CB-CG 4.31Å
344	F	96.6	Very high	96.5	Very high	127 Å²	127	48.8 Å²	48.8	56%	0.557	24%	0.237	S	C	*	.	H	α-helix	trans	-109.4	-2.8	-161.5	-57.2	-63.1	0	0	0	114.2	M340 L412 V416	M340-F344 HydrophobicContact CB-CD2 4.31Å; M340-F344 HydrophobicContact CG-CE2 4.46Å; M340-F344 WeakPolarHBondContact O-CD2 3.49Å; M340-F344 PolarHBondContact O-N 3.23Å; F344-L412 HydrophobicContact CD1-CD1 4.44Å; F344-L412 HydrophobicContact CE1-CD1 4.41Å; F344-V416 HydrophobicContact CE1-CG2 4.1Å; F344-V416 HydrophobicContact CZ-CG2 3.79Å
345	T	94.5	Very high	96.5	Very high	36 Å²	36	50.6 Å²	50.6	22%	0.221	24%	0.244	C	C	.	.			trans	-123.5	169.1	179.2	84.1	0	0	0	0	111.7	K288 M341 W347	K288-T345 WeakPolarHBondContact CE-O 3.4Å; K288-T345 PolarHBondContact NZ-O 3.12Å; M341-T345 WeakPolarHBondContact O-CB 3.46Å; M341-T345 PolarHBondContact O-N 3.11Å; M341-T345 PolarHBondContact O-OG1 3.3Å; T345-W347 PolarHBondContact OG1-N 3.41Å
346	F	92.3	Very high	96.4	Very high	159 Å²	159	50.6 Å²	50.6	70%	0.697	24%	0.244	S	C	*	.			trans	-115.2	27.2	166.1	-65.3	-86.4	0	0	0	110.6	K288	K288-F346 HydrophobicContact CG-CE1 4.18Å
347	W	92.1	Very high	96.3	Very high	162 Å²	162	49.5 Å²	49.5	61%	0.614	24%	0.238	S	C	*	.	S	Bend	trans	-62.6	157.6	173.1	-73	13.1	0	0	0	110.1	F289 M341 T345 P349	F289-W347 VanDerWaalsContact CE1-O 3.26Å; F289-W347 WeakPolarHBondContact CE1-O 3.42Å; M341-W347 HydrophobicContact CE-CE3 3.72Å; M341-W347 HydrophobicContact CE-CZ3 4.21Å; T345-W347 PolarHBondContact OG1-N 3.41Å; W347-P349 VanDerWaalsContact O-CD 3.3Å; W347-P349 WeakPolarHBondContact O-CD 3.36Å
348	N	93.2	Very high	96.3	Very high	88 Å²	88	49.9 Å²	49.9	47%	0.471	24%	0.239	S	C	.	.			trans	-54.1	114.9	179.1	-174.8	-29.4	0	0	0	110.1	W350 I351	N348-W350 PolarHBondContact O-N 3.37Å; N348-W350 VanDerWaalsContact O-N 3.08Å; N348-W350 VanDerWaalsContact OD1-CB 3.28Å; N348-W350 WeakPolarHBondContact OD1-CB 3.43Å; N348-W350 PolarHBondContact OD1-N 2.87Å; N348-W350 VanDerWaalsContact OD1-N 3.11Å; N348-I351 HydrophobicContact CB-CD1 4.34Å; N348-I351 HydrophobicContact CB-CG1 4.46Å; N348-I351 WeakPolarHBondContact O-CB 3.49Å; N348-I351 PolarHBondContact O-N 3.37Å
349	P	95.3	Very high	96.2	Very high	4 Å²	4	49.9 Å²	49.9	3%	0.026	24%	0.239	C	C	.	.	H	α-helix	trans	-65	-18.4	-171.4	24.6	-34.5	0	0	0	112.8	F285 F289 F291 V299 L342 W347 I351 A352 M353	F285-P349 HydrophobicContact CD1-CB 3.91Å; F285-P349 HydrophobicContact CD1-CG 4.28Å; F285-P349 HydrophobicContact CE1-CB 3.64Å; F285-P349 HydrophobicContact CE1-CG 4.47Å; F289-P349 HydrophobicContact CD1-CG 4.06Å; F289-P349 HydrophobicContact CD2-CB 4.47Å; F289-P349 HydrophobicContact CD2-CG 4.41Å; F289-P349 HydrophobicContact CE1-CB 4.33Å; F289-P349 HydrophobicContact CE1-CG 4.3Å; F289-P349 HydrophobicContact CE2-CB 4.27Å; F289-P349 HydrophobicContact CG-CG 4.11Å; F289-P349 HydrophobicContact CZ-CB 4.2Å; F291-P349 HydrophobicContact CD2-CG 4.45Å; F291-P349 HydrophobicContact CE1-CG 4.18Å; F291-P349 HydrophobicContact CE2-CG 3.45Å; F291-P349 VanDerWaalsContact CE2-CG 3.45Å; F291-P349 HydrophobicContact CZ-CG 3.29Å; V299-P349 HydrophobicContact CG2-CB 4.41Å; V299-P349 HydrophobicContact CG2-CG 4.47Å; L342-P349 HydrophobicContact CD2-CB 4.23Å; W347-P349 VanDerWaalsContact O-CD 3.3Å; W347-P349 WeakPolarHBondContact O-CD 3.36Å; P349-I351 PolarHBondContact O-N 2.9Å; P349-A352 PolarHBondContact O-N 3.25Å; P349-M353 WeakPolarHBondContact O-CB 3.21Å; P349-M353 VanDerWaalsContact O-CG 3.31Å; P349-M353 WeakPolarHBondContact O-CG 3.44Å; P349-M353 PolarHBondContact O-N 2.85Å
350	W	96.8	Very high	96.1	Very high	90 Å²	90	50 Å²	50	34%	0.341	24%	0.24	S	C	.	.	H	α-helix	trans	-57.6	-31.8	172.4	-69.8	87.5	0	0	0	112.5	F291 A298 V299 I302 N348 S354	F291-W350 AromaticContact CE2-NE1 3.89Å; A298-W350 HydrophobicContact CB-CH2 3.79Å; A298-W350 HydrophobicContact CB-CZ2 4.11Å; V299-W350 HydrophobicContact CB-CD2 4.04Å; V299-W350 HydrophobicContact CB-CE3 4.38Å; V299-W350 HydrophobicContact CB-CH2 4.23Å; V299-W350 HydrophobicContact CB-CZ2 3.87Å; V299-W350 HydrophobicContact CB-CZ3 4.46Å; V299-W350 HydrophobicContact CG2-CB 4.39Å; V299-W350 HydrophobicContact CG2-CD2 3.65Å; V299-W350 HydrophobicContact CG2-CE3 4.05Å; V299-W350 HydrophobicContact CG2-CG 3.79Å; V299-W350 HydrophobicContact CG2-CZ2 4.42Å; I302-W350 HydrophobicContact CB-CE3 4.27Å; I302-W350 HydrophobicContact CB-CZ3 4.01Å; I302-W350 HydrophobicContact CD1-CE3 4.46Å; I302-W350 HydrophobicContact CD1-CZ3 4Å; I302-W350 HydrophobicContact CG1-CE3 4.09Å; I302-W350 HydrophobicContact CG1-CZ3 3.98Å; N348-W350 PolarHBondContact O-N 3.37Å; N348-W350 VanDerWaalsContact O-N 3.08Å; N348-W350 VanDerWaalsContact OD1-CB 3.28Å; N348-W350 WeakPolarHBondContact OD1-CB 3.43Å; N348-W350 PolarHBondContact OD1-N 2.87Å; N348-W350 VanDerWaalsContact OD1-N 3.11Å; W350-S354 WeakPolarHBondContact O-CB 3.46Å; W350-S354 PolarHBondContact O-N 3.49Å; W350-S354 PolarHBondContact O-OG 3.39Å
351	I	97	Very high	95.9	Very high	93 Å²	93	45.9 Å²	45.9	48%	0.477	22%	0.219	S	C	.	.	H	α-helix	trans	-68.4	-51.5	177.7	-55.5	173.8	0	0	0	110	M341 N348 P349 M353 S354 L355	M341-I351 HydrophobicContact CE-CB 4.06Å; M341-I351 HydrophobicContact CE-CG2 3.68Å; N348-I351 HydrophobicContact CB-CD1 4.34Å; N348-I351 HydrophobicContact CB-CG1 4.46Å; N348-I351 WeakPolarHBondContact O-CB 3.49Å; N348-I351 PolarHBondContact O-N 3.37Å; P349-I351 PolarHBondContact O-N 2.9Å; I351-M353 PolarHBondContact O-N 3.39Å; I351-S354 PolarHBondContact O-N 3.18Å; I351-L355 PolarHBondContact O-N 2.81Å
352	A	97.2	Very high	95.8	Very high	2 Å²	2	45.1 Å²	45.1	2%	0.017	22%	0.215	C	C	.	.	H	α-helix	trans	-63.4	-42.4	-179.6	0	0	0	0	0	111.5	A338 M341 L342 P349 S354 L355 L356	A338-A352 HydrophobicContact CB-CB 4.47Å; A338-A352 WeakPolarHBondContact CB-O 3.3Å; M341-A352 HydrophobicContact CB-CB 4.04Å; M341-A352 HydrophobicContact CE-CB 4.16Å; L342-A352 HydrophobicContact CD1-CB 4.27Å; L342-A352 HydrophobicContact CD2-CB 3.8Å; L342-A352 HydrophobicContact CG-CB 3.68Å; P349-A352 PolarHBondContact O-N 3.25Å; A352-S354 VanDerWaalsContact C-N 3.34Å; A352-S354 PolarHBondContact O-N 3.48Å; A352-L355 PolarHBondContact O-N 3.25Å; A352-L356 WeakPolarHBondContact O-CB 3.37Å; A352-L356 PolarHBondContact O-N 2.93Å
353	M	97.1	Very high	95.7	Very high	0 Å²	0	45 Å²	45	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-69.4	-31.5	178.5	-66.8	-57.5	-84	0	0	113.2	F277 F285 V299 I302 V303 L342 P349 I351 L356 G357	F277-M353 HydrophobicContact CE1-CE 3.67Å; F277-M353 HydrophobicContact CE1-SD 3.51Å; F277-M353 VanDerWaalsContact CE1-SD 3.51Å; F277-M353 HydrophobicContact CZ-CE 4.4Å; F277-M353 HydrophobicContact CZ-SD 3.97Å; F285-M353 HydrophobicContact CE1-CG 4.28Å; F285-M353 HydrophobicContact CE2-CE 4.01Å; F285-M353 HydrophobicContact CE2-CG 4.41Å; F285-M353 HydrophobicContact CE2-SD 4.42Å; F285-M353 HydrophobicContact CZ-CE 3.87Å; F285-M353 HydrophobicContact CZ-CG 3.63Å; F285-M353 HydrophobicContact CZ-SD 3.68Å; V299-M353 HydrophobicContact CG2-CB 4.2Å; V299-M353 HydrophobicContact CG2-CG 3.99Å; I302-M353 HydrophobicContact CG2-CB 3.43Å; I302-M353 VanDerWaalsContact CG2-CB 3.43Å; V303-M353 HydrophobicContact CG2-CB 4.43Å; V303-M353 HydrophobicContact CG2-CE 3.37Å; V303-M353 HydrophobicContact CG2-SD 4.19Å; L342-M353 HydrophobicContact CD1-SD 4.21Å; P349-M353 WeakPolarHBondContact O-CB 3.21Å; P349-M353 VanDerWaalsContact O-CG 3.31Å; P349-M353 WeakPolarHBondContact O-CG 3.44Å; P349-M353 PolarHBondContact O-N 2.85Å; I351-M353 PolarHBondContact O-N 3.39Å; M353-L356 HydrophobicContact CE-CD2 4.4Å; M353-L356 PolarHBondContact O-N 3.23Å; M353-L356 HydrophobicContact SD-CD2 3.92Å; M353-G357 PolarHBondContact O-N 2.87Å
354	S	97.7	Very high	95.4	Very high	39 Å²	39	45.6 Å²	45.6	27%	0.273	22%	0.22	S	C	.	.	H	α-helix	trans	-68.3	-43.7	172.7	-60.9	0	0	0	0	111.6	I306 W350 I351 A352 L356 G357 V358	I306-S354 VanDerWaalsContact CD1-CA 3.49Å; W350-S354 WeakPolarHBondContact O-CB 3.46Å; W350-S354 PolarHBondContact O-N 3.49Å; W350-S354 PolarHBondContact O-OG 3.39Å; I351-S354 PolarHBondContact O-N 3.18Å; A352-S354 VanDerWaalsContact C-N 3.34Å; A352-S354 PolarHBondContact O-N 3.48Å; S354-L356 VanDerWaalsContact C-N 3.29Å; S354-L356 PolarHBondContact O-N 3.36Å; S354-G357 PolarHBondContact O-N 2.86Å; S354-V358 PolarHBondContact O-N 2.96Å; S354-V358 VanDerWaalsContact O-N 3.07Å
355	L	97.6	Very high	95	Very high	59 Å²	59	40.4 Å²	40.4	31%	0.309	20%	0.199	S	C	.	.	H	α-helix	trans	-60.4	-41.8	173.8	-175.4	61.8	0	0	0	111.1	A334 C337 A338 M341 I351 A352 V358 S359	A334-L355 HydrophobicContact CB-CD1 3.82Å; A334-L355 HydrophobicContact CB-CG 4.14Å; A334-L355 VanDerWaalsContact O-CD2 3.3Å; A334-L355 WeakPolarHBondContact O-CD2 3.44Å; C337-L355 HydrophobicContact CB-CD2 4.01Å; A338-L355 HydrophobicContact CB-CB 4.43Å; A338-L355 HydrophobicContact CB-CD2 4.3Å; A338-L355 HydrophobicContact CB-CG 4.44Å; M341-L355 HydrophobicContact SD-CD2 4.49Å; I351-L355 PolarHBondContact O-N 2.81Å; A352-L355 PolarHBondContact O-N 3.25Å; L355-V358 PolarHBondContact O-N 3.46Å; L355-S359 WeakPolarHBondContact O-CB 3.28Å; L355-S359 PolarHBondContact O-N 3.49Å; L355-S359 PolarHBondContact O-OG 3.43Å; L355-S359 VanDerWaalsContact O-OG 3.13Å
356	L	97.1	Very high	94.9	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-59.2	-48	175.3	-162.7	65.8	0	0	0	111.2	I274 F277 V303 T335 A338 A352 M353 S354 V358 S359 Y360	I274-L356 HydrophobicContact CD1-CD1 3.39Å; I274-L356 HydrophobicContact CD1-CD2 4.39Å; I274-L356 HydrophobicContact CD1-CG 3.95Å; F277-L356 HydrophobicContact CD1-CD2 3.97Å; F277-L356 HydrophobicContact CE1-CD2 3.96Å; V303-L356 HydrophobicContact CG2-CB 4.32Å; V303-L356 HydrophobicContact CG2-CD2 4.09Å; V303-L356 HydrophobicContact CG2-CG 4.45Å; T335-L356 HydrophobicContact CG2-CD1 3.77Å; A338-L356 HydrophobicContact CB-CB 4.21Å; A338-L356 HydrophobicContact CB-CD1 4.12Å; A352-L356 WeakPolarHBondContact O-CB 3.37Å; A352-L356 PolarHBondContact O-N 2.93Å; M353-L356 HydrophobicContact CE-CD2 4.4Å; M353-L356 PolarHBondContact O-N 3.23Å; M353-L356 HydrophobicContact SD-CD2 3.92Å; S354-L356 VanDerWaalsContact C-N 3.29Å; S354-L356 PolarHBondContact O-N 3.36Å; L356-V358 PolarHBondContact O-N 3.03Å; L356-S359 WeakPolarHBondContact CA-OG 3.36Å; L356-S359 PolarHBondContact O-N 3.49Å; L356-S359 PolarHBondContact O-OG 3.26Å; L356-Y360 WeakPolarHBondContact O-CB 3.44Å; L356-Y360 PolarHBondContact O-N 2.99Å
357	G	96.7	Very high	95	Very high	0 Å²	0	31.1 Å²	31.1	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-58.4	-43.7	176.5	0	0	0	0	0	114.4	M353 S354 S361	M353-G357 PolarHBondContact O-N 2.87Å; S354-G357 PolarHBondContact O-N 2.86Å; G357-S361 WeakPolarHBondContact O-CB 3.27Å; G357-S361 PolarHBondContact O-N 3.44Å
358	V	96.8	Very high	94.9	Very high	63 Å²	63	26.2 Å²	26.2	38%	0.382	14%	0.137	S	C	.	.	H	α-helix	trans	-66.2	-47.7	175.6	176.4	0	0	0	0	110.9	I306 L314 S354 L355 L356 Y360 S361 L362	I306-V358 HydrophobicContact CG2-CG2 3.65Å; L314-V358 HydrophobicContact CD1-CG1 4.38Å; S354-V358 PolarHBondContact O-N 2.96Å; S354-V358 VanDerWaalsContact O-N 3.07Å; L355-V358 PolarHBondContact O-N 3.46Å; L356-V358 PolarHBondContact O-N 3.03Å; V358-Y360 VanDerWaalsContact C-N 3.32Å; V358-Y360 PolarHBondContact O-N 3.15Å; V358-S361 WeakPolarHBondContact O-CB 3.35Å; V358-S361 PolarHBondContact O-N 3.02Å; V358-L362 WeakPolarHBondContact O-CB 3.34Å; V358-L362 PolarHBondContact O-N 3.2Å
359	S	97.4	Very high	94.6	Very high	1 Å²	1	23.9 Å²	23.9	1%	0.007	13%	0.126	C	C	.	.	H	α-helix	trans	-61.8	-41.4	-178.9	66.8	0	0	0	0	112.3	Y270 A331 T335 L355 L356 S361 L362 L363	Y270-S359 PolarHBondContact OH-O 2.96Å; Y270-S359 PolarHBondContact OH-OG 2.94Å; A331-S359 WeakPolarHBondContact O-CB 3.46Å; T335-S359 VanDerWaalsContact OG1-CB 3.24Å; T335-S359 WeakPolarHBondContact OG1-CB 3.06Å; T335-S359 PolarHBondContact OG1-OG 3.31Å; L355-S359 WeakPolarHBondContact O-CB 3.28Å; L355-S359 PolarHBondContact O-N 3.49Å; L355-S359 PolarHBondContact O-OG 3.43Å; L355-S359 VanDerWaalsContact O-OG 3.13Å; L356-S359 WeakPolarHBondContact CA-OG 3.36Å; L356-S359 PolarHBondContact O-N 3.49Å; L356-S359 PolarHBondContact O-OG 3.26Å; S359-S361 VanDerWaalsContact C-N 3.34Å; S359-S361 PolarHBondContact O-N 3.34Å; S359-L362 PolarHBondContact O-N 3.48Å; S359-L363 PolarHBondContact O-N 3.25Å
360	Y	95.2	Very high	94.3	Very high	3 Å²	3	23.7 Å²	23.7	1%	0.012	13%	0.125	C	C	.	.	H	α-helix	trans	-59.6	-45.7	177.1	174.8	-118.3	0	0	0	112	R176 Y270 Y271 I274 F275 V303 L356 V358 A364	R176-Y360 VanDerWaalsContact CZ-CZ 3.5Å; R176-Y360 VanDerWaalsContact NH1-CE1 3.3Å; R176-Y360 PolarHBondContact NH1-OH 3.34Å; R176-Y360 PolarHBondContact NH2-OH 3.4Å; Y270-Y360 HydrophobicContact CE1-CD2 4.32Å; Y270-Y360 VanDerWaalsContact OH-CA 3.29Å; Y270-Y360 WeakPolarHBondContact OH-CA 3.49Å; Y270-Y360 PolarHBondContact OH-N 2.89Å; Y270-Y360 VanDerWaalsContact OH-N 3.16Å; Y271-Y360 AromaticContact CD1-CE2 3.9Å; Y271-Y360 HydrophobicContact CD1-CE2 3.9Å; Y271-Y360 HydrophobicContact CE1-CD2 4.09Å; Y271-Y360 AromaticContact CE1-CE2 3.51Å; Y271-Y360 HydrophobicContact CE1-CE2 3.51Å; I274-Y360 HydrophobicContact CG1-CD2 4.33Å; I274-Y360 HydrophobicContact CG2-CD2 3.9Å; I274-Y360 HydrophobicContact CG2-CE2 4.03Å; F275-Y360 HydrophobicContact CZ-CE2 4.3Å; F275-Y360 WeakPolarHBondContact CZ-OH 3.48Å; V303-Y360 HydrophobicContact CG1-CD1 4.46Å; L356-Y360 WeakPolarHBondContact O-CB 3.44Å; L356-Y360 PolarHBondContact O-N 2.99Å; V358-Y360 VanDerWaalsContact C-N 3.32Å; V358-Y360 PolarHBondContact O-N 3.15Å; Y360-A364 WeakPolarHBondContact O-CB 3.38Å; Y360-A364 PolarHBondContact O-N 3.36Å; Y360-A364 VanDerWaalsContact O-N 3.14Å
361	S	93.7	Very high	94	Very high	0 Å²	0	19.4 Å²	19.4	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-64.1	-43.8	175.7	-169.1	0	0	0	0	112.1	A310 S311 G357 V358 S359 A364 C365	A310-S361 VanDerWaalsContact C-OG 3.23Å; S311-S361 WeakPolarHBondContact CA-OG 3.47Å; S311-S361 PolarHBondContact N-OG 3.43Å; S311-S361 PolarHBondContact OG-OG 3.38Å; G357-S361 WeakPolarHBondContact O-CB 3.27Å; G357-S361 PolarHBondContact O-N 3.44Å; V358-S361 WeakPolarHBondContact O-CB 3.35Å; V358-S361 PolarHBondContact O-N 3.02Å; S359-S361 VanDerWaalsContact C-N 3.34Å; S359-S361 PolarHBondContact O-N 3.34Å; S361-A364 PolarHBondContact O-N 3.44Å; S361-C365 PolarHBondContact O-N 3.34Å; S361-C365 PolarHBondContact O-SG 3.38Å
362	L	94.7	Very high	93.4	Very high	16 Å²	16	17 Å²	17	8%	0.084	10%	0.103	C	C	.	.	H	α-helix	trans	-63.8	-45.1	-179.1	-177.3	59.7	0	0	0	111.8	L314 V318 W327 A330 A331 V358 S359 C365 A366	L314-L362 HydrophobicContact CB-CD1 4.47Å; L314-L362 HydrophobicContact CD1-CB 4.07Å; L314-L362 HydrophobicContact CD1-CD1 4.49Å; L314-L362 HydrophobicContact CD2-CD1 4.39Å; V318-L362 HydrophobicContact CG2-CD1 4.01Å; W327-L362 HydrophobicContact CB-CD1 4.07Å; W327-L362 HydrophobicContact CB-CG 4.42Å; W327-L362 HydrophobicContact CD2-CD1 4.08Å; W327-L362 HydrophobicContact CE3-CD1 3.67Å; W327-L362 HydrophobicContact CE3-CD2 3.98Å; W327-L362 HydrophobicContact CE3-CG 4.38Å; W327-L362 HydrophobicContact CG-CD1 4.3Å; W327-L362 HydrophobicContact CZ3-CD1 4.4Å; A330-L362 HydrophobicContact CB-CD2 4.31Å; A331-L362 HydrophobicContact CB-CB 4.06Å; A331-L362 HydrophobicContact CB-CD2 3.98Å; A331-L362 HydrophobicContact CB-CG 4.02Å; V358-L362 WeakPolarHBondContact O-CB 3.34Å; V358-L362 PolarHBondContact O-N 3.2Å; S359-L362 PolarHBondContact O-N 3.48Å; L362-C365 PolarHBondContact O-N 2.87Å; L362-A366 WeakPolarHBondContact O-CB 3.38Å; L362-A366 PolarHBondContact O-N 3.48Å; L362-A366 VanDerWaalsContact O-N 3.08Å
363	L	95.2	Very high	92.8	Very high	0 Å²	0	20 Å²	20	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-64.2	-44.7	178.3	-171.5	116.7	0	0	0	111.5	I266 Y270 Y271 V328 A331 V332 S359 C365 A366 L367	I266-L363 HydrophobicContact CG2-CD1 4.36Å; Y270-L363 HydrophobicContact CD1-CB 4.4Å; Y270-L363 HydrophobicContact CD1-CD1 4.07Å; Y270-L363 HydrophobicContact CD1-CD2 3.21Å; Y270-L363 HydrophobicContact CD1-CG 4.03Å; Y270-L363 HydrophobicContact CD2-CD1 3.6Å; Y270-L363 HydrophobicContact CD2-CD2 4.34Å; Y270-L363 HydrophobicContact CD2-CG 4.42Å; Y270-L363 HydrophobicContact CE1-CB 3.85Å; Y270-L363 HydrophobicContact CE1-CD1 4.19Å; Y270-L363 HydrophobicContact CE1-CD2 3.51Å; Y270-L363 HydrophobicContact CE1-CG 4.01Å; Y270-L363 HydrophobicContact CE2-CB 4.35Å; Y270-L363 HydrophobicContact CE2-CD1 3.73Å; Y270-L363 HydrophobicContact CE2-CG 4.39Å; Y270-L363 HydrophobicContact CG-CD1 3.74Å; Y270-L363 HydrophobicContact CG-CD2 3.66Å; Y270-L363 HydrophobicContact CG-CG 4.22Å; Y271-L363 HydrophobicContact CE1-CD2 4.4Å; Y271-L363 HydrophobicContact CE2-CD2 4.12Å; V328-L363 HydrophobicContact CG1-CD1 3.93Å; A331-L363 HydrophobicContact CB-CB 3.83Å; A331-L363 HydrophobicContact CB-CD1 4.25Å; V332-L363 HydrophobicContact CG2-CD1 3.85Å; S359-L363 PolarHBondContact O-N 3.25Å; L363-C365 VanDerWaalsContact C-N 3.27Å; L363-C365 PolarHBondContact O-N 3.14Å; L363-A366 PolarHBondContact O-N 3.3Å; L363-L367 HydrophobicContact CD2-CB 4.36Å; L363-L367 HydrophobicContact CD2-CD2 3.77Å; L363-L367 HydrophobicContact CG-CB 4.21Å; L363-L367 HydrophobicContact CG-CD2 4.28Å; L363-L367 WeakPolarHBondContact O-CB 3.25Å; L363-L367 PolarHBondContact O-N 3.45Å
364	A	90	Very high	92.3	Very high	15 Å²	15	21.5 Å²	21.5	12%	0.124	12%	0.124	C	C	.	.	H	α-helix	trans	-57.6	-42.6	179.1	0	0	0	0	0	111.8	Y360 S361	Y360-A364 WeakPolarHBondContact O-CB 3.38Å; Y360-A364 PolarHBondContact O-N 3.36Å; Y360-A364 VanDerWaalsContact O-N 3.14Å; S361-A364 PolarHBondContact O-N 3.44Å
365	C	88.5	Confident	91.8	Very high	18 Å²	18	20.2 Å²	20.2	12%	0.122	12%	0.115	C	C	.	.	H	α-helix	trans	-72.9	-31.4	-179.9	-66.1	0	0	0	0	114	S311 S361 L362 L363 P369	S311-C365 PolarHBondContact O-SG 3.2Å; S361-C365 PolarHBondContact O-N 3.34Å; S361-C365 PolarHBondContact O-SG 3.38Å; L362-C365 PolarHBondContact O-N 2.87Å; L363-C365 VanDerWaalsContact C-N 3.27Å; L363-C365 PolarHBondContact O-N 3.14Å; C365-P369 WeakPolarHBondContact O-CD 3.48Å; C365-P369 WeakPolarHBondContact O-CG 3.38Å
366	A	91.6	Very high	91.1	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-93.6	-34	-176.4	0	0	0	0	0	113.8	V318 W327 V328 L362 L363 M370	V318-A366 HydrophobicContact CG1-CB 4.06Å; V318-A366 HydrophobicContact CG2-CB 4.33Å; W327-A366 HydrophobicContact CB-CB 3.8Å; V328-A366 HydrophobicContact CG2-CB 3.69Å; L362-A366 WeakPolarHBondContact O-CB 3.38Å; L362-A366 PolarHBondContact O-N 3.48Å; L362-A366 VanDerWaalsContact O-N 3.08Å; L363-A366 PolarHBondContact O-N 3.3Å; A366-M370 WeakPolarHBondContact O-CE 3.37Å; A366-M370 WeakPolarHBondContact O-CG 3.47Å
367	L	94.1	Very high	90.2	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-79.1	-49.4	-172.6	-173.7	69.8	0	0	0	113.1	I263 I266 C267 V328 L363 M370 M387	I263-L367 HydrophobicContact CG2-CD1 3.91Å; I263-L367 HydrophobicContact CG2-CG 4.3Å; I266-L367 HydrophobicContact CB-CD1 4.16Å; I266-L367 HydrophobicContact CD1-CD1 4.48Å; I266-L367 HydrophobicContact CG2-CD1 3.84Å; I266-L367 HydrophobicContact CG2-CD2 4.06Å; C267-L367 HydrophobicContact CB-CD2 3.89Å; V328-L367 HydrophobicContact CG1-CD1 4.36Å; V328-L367 HydrophobicContact CG2-CB 4.08Å; V328-L367 HydrophobicContact CG2-CD1 4.28Å; L363-L367 HydrophobicContact CD2-CB 4.36Å; L363-L367 HydrophobicContact CD2-CD2 3.77Å; L363-L367 HydrophobicContact CG-CB 4.21Å; L363-L367 HydrophobicContact CG-CD2 4.28Å; L363-L367 WeakPolarHBondContact O-CB 3.25Å; L363-L367 PolarHBondContact O-N 3.45Å; L367-M370 HydrophobicContact CB-CE 4.46Å; L367-M370 HydrophobicContact CD1-CE 3.69Å; L367-M370 WeakPolarHBondContact O-CB 3.45Å; L367-M370 PolarHBondContact O-N 3.43Å; L367-M387 HydrophobicContact CD2-CE 4.03Å; L367-M387 HydrophobicContact CG-CE 4.1Å
368	W	90.3	Very high	89.3	Confident	60 Å²	60	32.9 Å²	32.9	23%	0.227	18%	0.178	C	C	.	.	H	α-helix	trans	-62.9	-45.4	-172.8	-73.7	80.9	0	0	0	113.2	Y271 M370 V371 Y384 M387 Q388	Y271-W368 HydrophobicContact CE2-CZ2 4.32Å; Y271-W368 AromaticContact CE2-NE1 3.67Å; Y271-W368 AromaticContact CZ-NE1 3.69Å; Y271-W368 PolarHBondContact OH-NE1 2.99Å; W368-M370 PolarHBondContact O-N 3.45Å; W368-M370 VanDerWaalsContact O-N 3.14Å; W368-V371 PolarHBondContact O-N 3.4Å; W368-Y384 AromaticContact CE3-CD1 3.91Å; W368-Y384 HydrophobicContact CE3-CD1 3.91Å; W368-Y384 HydrophobicContact CE3-CE1 4.01Å; W368-Y384 HydrophobicContact CZ3-CD1 4.17Å; W368-Y384 WeakPolarHBondContact O-CE1 3.33Å; W368-Y384 PolarHBondContact O-OH 3.41Å; W368-Y384 VanDerWaalsContact O-OH 3.11Å; W368-M387 HydrophobicContact CD2-CE 3.69Å; W368-M387 HydrophobicContact CD2-SD 4.25Å; W368-M387 HydrophobicContact CE3-CE 4.01Å; W368-M387 HydrophobicContact CE3-SD 3.95Å; W368-M387 HydrophobicContact CG-CE 4.06Å; W368-M387 HydrophobicContact CH2-CE 4.4Å; W368-M387 HydrophobicContact CH2-CG 4.45Å; W368-M387 HydrophobicContact CH2-SD 4.48Å; W368-M387 HydrophobicContact CZ2-CE 4.11Å; W368-M387 HydrophobicContact CZ3-CE 4.36Å; W368-M387 HydrophobicContact CZ3-CG 4.43Å; W368-M387 HydrophobicContact CZ3-SD 4.08Å; W368-Q388 HydrophobicContact CH2-CB 4.45Å
369	P	87	Confident	88.5	Confident	38 Å²	38	30.9 Å²	30.9	25%	0.247	16%	0.164	C	C	.	.	H	α-helix	trans	-60.6	-25.7	178.1	-25.9	37	0	0	0	114.1	C365 V371 A372 F373	C365-P369 WeakPolarHBondContact O-CD 3.48Å; C365-P369 WeakPolarHBondContact O-CG 3.38Å; P369-V371 PolarHBondContact O-N 3.03Å; P369-A372 PolarHBondContact O-N 2.91Å; P369-F373 HydrophobicContact CB-CE1 4.4Å; P369-F373 HydrophobicContact CB-CE2 4.01Å; P369-F373 HydrophobicContact CB-CZ 3.68Å; P369-F373 WeakPolarHBondContact O-CD1 3.38Å; P369-F373 PolarHBondContact O-N 3.25Å
370	M	89.1	Confident	87.7	Confident	0 Å²	0	32.7 Å²	32.7	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-62.6	-27.1	179.7	-70.9	-168.3	-74.2	0	0	113.4	I263 N324 I325 V328 A366 L367 W368 A372 F373 V374 L432 L443	I263-M370 HydrophobicContact CD1-CB 3.78Å; N324-M370 HydrophobicContact CB-CE 4.48Å; N324-M370 HydrophobicContact CB-CG 3.73Å; N324-M370 HydrophobicContact CB-SD 3.6Å; I325-M370 HydrophobicContact CG1-SD 4.1Å; V328-M370 HydrophobicContact CG2-CE 3.62Å; A366-M370 WeakPolarHBondContact O-CE 3.37Å; A366-M370 WeakPolarHBondContact O-CG 3.47Å; L367-M370 HydrophobicContact CB-CE 4.46Å; L367-M370 HydrophobicContact CD1-CE 3.69Å; L367-M370 WeakPolarHBondContact O-CB 3.45Å; L367-M370 PolarHBondContact O-N 3.43Å; W368-M370 PolarHBondContact O-N 3.45Å; W368-M370 VanDerWaalsContact O-N 3.14Å; M370-A372 VanDerWaalsContact C-N 3.26Å; M370-A372 PolarHBondContact O-N 2.9Å; M370-F373 HydrophobicContact CB-CD2 4.39Å; M370-F373 HydrophobicContact CG-CD2 4.15Å; M370-F373 HydrophobicContact CG-CE2 4.43Å; M370-F373 PolarHBondContact O-N 2.93Å; M370-V374 WeakPolarHBondContact O-CG2 3.09Å; M370-V374 PolarHBondContact O-N 3.37Å; M370-L432 HydrophobicContact CE-CD2 4.35Å; M370-L432 HydrophobicContact SD-CD2 4.43Å; M370-L443 HydrophobicContact CB-CD2 3.96Å; M370-L443 HydrophobicContact CG-CD2 3.99Å; M370-L443 HydrophobicContact SD-CB 4.45Å; M370-L443 HydrophobicContact SD-CD1 4.49Å; M370-L443 HydrophobicContact SD-CD2 4.17Å
371	V	89.4	Confident	87	Confident	0 Å²	0	33.8 Å²	33.8	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-58.2	-44.5	173.9	175.2	0	0	0	0	110.3	L260 I263 W368 P369 F373 V374 V375 A383 Y384 M387	L260-V371 HydrophobicContact CD1-CB 4.39Å; L260-V371 HydrophobicContact CD1-CG1 4.06Å; L260-V371 HydrophobicContact CD1-CG2 4.12Å; I263-V371 HydrophobicContact CG2-CG2 4.01Å; W368-V371 PolarHBondContact O-N 3.4Å; P369-V371 PolarHBondContact O-N 3.03Å; V371-F373 PolarHBondContact O-N 3.37Å; V371-V374 PolarHBondContact O-N 2.92Å; V371-V375 HydrophobicContact CG1-CG2 4.34Å; V371-V375 WeakPolarHBondContact O-CB 3.49Å; V371-V375 WeakPolarHBondContact O-CG2 3.32Å; V371-V375 PolarHBondContact O-N 3.41Å; V371-V375 VanDerWaalsContact O-N 3.14Å; V371-A383 HydrophobicContact CG1-CB 3.65Å; V371-Y384 HydrophobicContact CB-CD1 4.28Å; V371-Y384 HydrophobicContact CB-CE1 3.76Å; V371-Y384 HydrophobicContact CB-CE2 4.35Å; V371-Y384 HydrophobicContact CG1-CD1 4.2Å; V371-Y384 HydrophobicContact CG1-CD2 4.21Å; V371-Y384 HydrophobicContact CG1-CE1 4.09Å; V371-Y384 HydrophobicContact CG1-CE2 4.1Å; V371-Y384 HydrophobicContact CG1-CG 4.26Å; V371-Y384 HydrophobicContact CG2-CD1 4.49Å; V371-Y384 HydrophobicContact CG2-CE1 4.17Å; V371-M387 HydrophobicContact CG2-SD 3.48Å; V371-M387 WeakPolarHBondContact CG2-SD 3.5Å
372	A	85	Confident	86.5	Confident	43 Å²	43	33.9 Å²	33.9	36%	0.355	19%	0.186	S	C	.	.	H	α-helix	trans	-70.8	-15.3	178.4	0	0	0	0	0	114.2	P369 M370 L380 Y384	P369-A372 PolarHBondContact O-N 2.91Å; M370-A372 VanDerWaalsContact C-N 3.26Å; M370-A372 PolarHBondContact O-N 2.9Å; A372-L380 HydrophobicContact CB-CD2 3.87Å; A372-Y384 HydrophobicContact CB-CE2 4.39Å
373	F	85	Confident	86.2	Confident	65 Å²	65	33.1 Å²	33.1	29%	0.285	18%	0.182	S	C	.	.	H	α-helix	trans	-85.7	-24.2	177.1	-54.9	-22.9	0	0	0	112.6	N324 P369 M370 V371 L443	N324-F373 WeakPolarHBondContact ND2-CE2 3.38Å; P369-F373 HydrophobicContact CB-CE1 4.4Å; P369-F373 HydrophobicContact CB-CE2 4.01Å; P369-F373 HydrophobicContact CB-CZ 3.68Å; P369-F373 WeakPolarHBondContact O-CD1 3.38Å; P369-F373 PolarHBondContact O-N 3.25Å; M370-F373 HydrophobicContact CB-CD2 4.39Å; M370-F373 HydrophobicContact CG-CD2 4.15Å; M370-F373 HydrophobicContact CG-CE2 4.43Å; M370-F373 PolarHBondContact O-N 2.93Å; V371-F373 PolarHBondContact O-N 3.37Å; F373-L443 HydrophobicContact CB-CD2 3.95Å; F373-L443 HydrophobicContact CD2-CD2 4.37Å
374	V	86.6	Confident	85.8	Confident	31 Å²	31	36.4 Å²	36.4	19%	0.188	20%	0.195	C	C	.	.	H	α-helix	trans	-102.7	-24.7	-174.1	-177.3	0	0	0	0	112.2	S257 L260 I263 M370 V371 L443	S257-V374 WeakPolarHBondContact OG-CG1 3.5Å; L260-V374 HydrophobicContact CB-CG1 4.44Å; I263-V374 HydrophobicContact CD1-CG2 4.29Å; M370-V374 WeakPolarHBondContact O-CG2 3.09Å; M370-V374 PolarHBondContact O-N 3.37Å; V371-V374 PolarHBondContact O-N 2.92Å; V374-L443 HydrophobicContact CG2-CD1 4.2Å; V374-L443 HydrophobicContact CG2-CD2 3.4Å; V374-L443 HydrophobicContact CG2-CG 4.1Å
375	V	86.1	Confident	85.7	Confident	12 Å²	12	36 Å²	36	7%	0.073	19%	0.192	C	C	.	.	S	Bend	trans	-105.8	134.7	-171.3	-178.8	0	0	0	0	110.1	L260 V371 Q379 L380 A383	L260-V375 HydrophobicContact CD1-CG2 3.8Å; L260-V375 HydrophobicContact CD2-CG2 3.48Å; L260-V375 VanDerWaalsContact CD2-CG2 3.48Å; L260-V375 HydrophobicContact CG-CG2 4.2Å; V371-V375 HydrophobicContact CG1-CG2 4.34Å; V371-V375 WeakPolarHBondContact O-CB 3.49Å; V371-V375 WeakPolarHBondContact O-CG2 3.32Å; V371-V375 PolarHBondContact O-N 3.41Å; V371-V375 VanDerWaalsContact O-N 3.14Å; V375-Q379 HydrophobicContact CG1-CB 3.46Å; V375-Q379 VanDerWaalsContact CG1-CB 3.46Å; V375-L380 HydrophobicContact CB-CD2 4.21Å; V375-L380 HydrophobicContact CG1-CD2 4.44Å; V375-A383 HydrophobicContact CB-CB 4.41Å; V375-A383 HydrophobicContact CG1-CB 4.01Å; V375-A383 HydrophobicContact CG2-CB 3.95Å
376	P	83.6	Confident	85.8	Confident	61 Å²	61	36.7 Å²	36.7	40%	0.396	19%	0.193	S	C	.	.			trans	-64.4	151.1	175.3	29	-36.3	0	0	0	110.9	H378 Q379	P376-H378 VanDerWaalsContact C-N 3.31Å; P376-H378 VanDerWaalsContact CG-CE1 3.43Å; P376-H378 WeakPolarHBondContact CG-CE1 3.39Å; P376-H378 PolarHBondContact O-N 2.86Å; P376-H378 VanDerWaalsContact O-N 3.15Å; P376-Q379 HydrophobicContact CG-CB 4.29Å; P376-Q379 HydrophobicContact CG-CG 4.13Å; P376-Q379 PolarHBondContact O-N 2.94Å
377	E	78.1	Confident	85.9	Confident	153 Å²	153	36.7 Å²	36.7	72%	0.715	19%	0.193	S	C	*	.	G	3₁₀ helix	trans	-48.3	-51.1	-172.3	-67.9	-174.4	171.3	0	0	112.5	E246 Q379 L380	E246-E377 VanDerWaalsContact CD-O 3.26Å; E377-Q379 PolarHBondContact O-N 2.85Å; E377-L380 HydrophobicContact CB-CD1 4.32Å; E377-L380 HydrophobicContact CG-CD1 4.37Å; E377-L380 VanDerWaalsContact O-CB 3.3Å; E377-L380 WeakPolarHBondContact O-CB 3.34Å; E377-L380 VanDerWaalsContact O-CG 3.25Å; E377-L380 WeakPolarHBondContact O-CG 3.31Å; E377-L380 PolarHBondContact O-N 3.26Å
378	H	78.2	Confident	85.8	Confident	112 Å²	112	38 Å²	38	52%	0.519	20%	0.199	S	C	.	.	G	3₁₀ helix	trans	-59	-12.8	-178.4	73.3	-80.5	0	0	0	116.8	P376	P376-H378 VanDerWaalsContact C-N 3.31Å; P376-H378 VanDerWaalsContact CG-CE1 3.43Å; P376-H378 WeakPolarHBondContact CG-CE1 3.39Å; P376-H378 PolarHBondContact O-N 2.86Å; P376-H378 VanDerWaalsContact O-N 3.15Å
379	Q	80.4	Confident	85.9	Confident	21 Å²	21	35.3 Å²	35.3	10%	0.098	19%	0.19	C	C	.	.	G	3₁₀ helix	trans	-109.6	-0.5	177.6	-63.9	-177.5	-8.2	0	0	113	D252 V375 P376 E377 G381 T382 A383	D252-Q379 HydrophobicContact CB-CG 4.08Å; V375-Q379 HydrophobicContact CG1-CB 3.46Å; V375-Q379 VanDerWaalsContact CG1-CB 3.46Å; P376-Q379 HydrophobicContact CG-CB 4.29Å; P376-Q379 HydrophobicContact CG-CG 4.13Å; P376-Q379 PolarHBondContact O-N 2.94Å; E377-Q379 PolarHBondContact O-N 2.85Å; Q379-G381 PolarHBondContact O-N 2.9Å; Q379-T382 PolarHBondContact O-N 2.62Å; Q379-T382 VanDerWaalsContact O-N 3.16Å; Q379-A383 PolarHBondContact O-N 3.28Å
380	L	80.7	Confident	86.3	Confident	38 Å²	38	35.8 Å²	35.8	20%	0.199	19%	0.189	C	C	.	.	H	α-helix	trans	-59.7	-47.5	-174.5	-73.7	174.2	0	0	0	112.3	A372 V375 E377 T382 A383 Y384	A372-L380 HydrophobicContact CB-CD2 3.87Å; V375-L380 HydrophobicContact CB-CD2 4.21Å; V375-L380 HydrophobicContact CG1-CD2 4.44Å; E377-L380 HydrophobicContact CB-CD1 4.32Å; E377-L380 HydrophobicContact CG-CD1 4.37Å; E377-L380 VanDerWaalsContact O-CB 3.3Å; E377-L380 WeakPolarHBondContact O-CB 3.34Å; E377-L380 VanDerWaalsContact O-CG 3.25Å; E377-L380 WeakPolarHBondContact O-CG 3.31Å; E377-L380 PolarHBondContact O-N 3.26Å; L380-T382 VanDerWaalsContact C-N 3.28Å; L380-T382 PolarHBondContact O-N 3.26Å; L380-A383 PolarHBondContact O-N 3.25Å; L380-Y384 HydrophobicContact CD2-CE2 4.37Å; L380-Y384 WeakPolarHBondContact O-CD2 3.31Å; L380-Y384 PolarHBondContact O-N 2.91Å
381	G	79	Confident	86.6	Confident	26 Å²	26	36.5 Å²	36.5	27%	0.268	19%	0.193	S	C	.	.	H	α-helix	trans	-56.8	-42.8	176.4	0	0	0	0	0	112.4	E246 Q379 G385	E246-G381 PolarHBondContact OE2-N 3.26Å; Q379-G381 PolarHBondContact O-N 2.9Å; G381-G385 PolarHBondContact O-N 3.07Å
382	T	84.1	Confident	86.9	Confident	2 Å²	2	36.6 Å²	36.6	1%	0.012	19%	0.193	C	C	.	.	H	α-helix	trans	-65.5	-43.7	177.4	-51.3	0	0	0	0	111.6	I248 K249 D252 V253 F256 Q379 L380 F386	I248-T382 HydrophobicContact CG2-CG2 4.29Å; K249-T382 PolarHBondContact N-OG1 2.92Å; K249-T382 WeakPolarHBondContact O-CG2 3.31Å; D252-T382 HydrophobicContact CB-CG2 4.17Å; D252-T382 PolarHBondContact OD2-OG1 3.49Å; V253-T382 HydrophobicContact CG2-CG2 4.17Å; F256-T382 HydrophobicContact CZ-CG2 4.17Å; Q379-T382 PolarHBondContact O-N 2.62Å; Q379-T382 VanDerWaalsContact O-N 3.16Å; L380-T382 VanDerWaalsContact C-N 3.28Å; L380-T382 PolarHBondContact O-N 3.26Å; T382-F386 WeakPolarHBondContact O-CB 3.2Å; T382-F386 PolarHBondContact O-N 3.48Å
383	A	88.4	Confident	87.5	Confident	0 Å²	0	37.7 Å²	37.7	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-67.7	-45.5	-177.8	0	0	0	0	0	112.9	F256 L260 V371 V375 Q379 L380 F386 M387	F256-A383 HydrophobicContact CE1-CB 4.39Å; F256-A383 HydrophobicContact CZ-CB 4.09Å; L260-A383 HydrophobicContact CD2-CB 4.23Å; V371-A383 HydrophobicContact CG1-CB 3.65Å; V375-A383 HydrophobicContact CB-CB 4.41Å; V375-A383 HydrophobicContact CG1-CB 4.01Å; V375-A383 HydrophobicContact CG2-CB 3.95Å; Q379-A383 PolarHBondContact O-N 3.28Å; L380-A383 PolarHBondContact O-N 3.25Å; A383-F386 PolarHBondContact O-N 3.16Å; A383-M387 WeakPolarHBondContact O-CB 3.45Å; A383-M387 PolarHBondContact O-N 3.26Å
384	Y	86.9	Confident	88.1	Confident	70 Å²	70	35.1 Å²	35.1	28%	0.275	18%	0.184	S	C	.	.	H	α-helix	trans	-65.9	-41.9	175	-79.7	-66.1	0	0	0	112	W368 V371 A372 L380 F386 M387 Q388	W368-Y384 AromaticContact CE3-CD1 3.91Å; W368-Y384 HydrophobicContact CE3-CD1 3.91Å; W368-Y384 HydrophobicContact CE3-CE1 4.01Å; W368-Y384 HydrophobicContact CZ3-CD1 4.17Å; W368-Y384 WeakPolarHBondContact O-CE1 3.33Å; W368-Y384 PolarHBondContact O-OH 3.41Å; W368-Y384 VanDerWaalsContact O-OH 3.11Å; V371-Y384 HydrophobicContact CB-CD1 4.28Å; V371-Y384 HydrophobicContact CB-CE1 3.76Å; V371-Y384 HydrophobicContact CB-CE2 4.35Å; V371-Y384 HydrophobicContact CG1-CD1 4.2Å; V371-Y384 HydrophobicContact CG1-CD2 4.21Å; V371-Y384 HydrophobicContact CG1-CE1 4.09Å; V371-Y384 HydrophobicContact CG1-CE2 4.1Å; V371-Y384 HydrophobicContact CG1-CG 4.26Å; V371-Y384 HydrophobicContact CG2-CD1 4.49Å; V371-Y384 HydrophobicContact CG2-CE1 4.17Å; A372-Y384 HydrophobicContact CB-CE2 4.39Å; L380-Y384 HydrophobicContact CD2-CE2 4.37Å; L380-Y384 WeakPolarHBondContact O-CD2 3.31Å; L380-Y384 PolarHBondContact O-N 2.91Å; Y384-F386 VanDerWaalsContact C-N 3.31Å; Y384-F386 PolarHBondContact O-N 2.96Å; Y384-M387 PolarHBondContact O-N 3.44Å; Y384-Q388 PolarHBondContact O-N 3.37Å
385	G	88.5	Confident	88.5	Confident	5 Å²	5	34.1 Å²	34.1	5%	0.052	18%	0.178	C	C	.	.	H	α-helix	trans	-59.1	-42.1	174.5	0	0	0	0	0	112.2	C90 G381 S389	C90-G385 WeakPolarHBondContact O-CA 3.35Å; G381-G385 PolarHBondContact O-N 3.07Å; G385-S389 VanDerWaalsContact O-CB 3.31Å; G385-S389 WeakPolarHBondContact O-CB 3.37Å; G385-S389 PolarHBondContact O-N 3.25Å; G385-S389 PolarHBondContact O-OG 2.99Å
386	F	90.9	Very high	89.1	Confident	33 Å²	33	33.6 Å²	33.6	15%	0.145	18%	0.175	C	C	.	.	H	α-helix	trans	-65.2	-46.8	175.3	-169.1	-85.3	0	0	0	112.1	F91 V253 F256 W261 F264 T382 A383 Y384 Q388 S389 I390	F91-F386 VanDerWaalsContact CE1-CA 3.47Å; F91-F386 HydrophobicContact CE1-CB 3.75Å; F91-F386 AromaticContact CE1-CD2 3.71Å; F91-F386 HydrophobicContact CE1-CD2 3.71Å; F91-F386 HydrophobicContact CE1-CG 4.17Å; F91-F386 HydrophobicContact CZ-CB 4.15Å; F91-F386 AromaticContact CZ-CD2 3.56Å; F91-F386 HydrophobicContact CZ-CD2 3.56Å; F91-F386 HydrophobicContact CZ-CE2 4.3Å; F91-F386 HydrophobicContact CZ-CG 4.17Å; V253-F386 HydrophobicContact CG1-CD2 3.95Å; V253-F386 HydrophobicContact CG1-CE2 3.67Å; V253-F386 HydrophobicContact CG1-CZ 4.24Å; V253-F386 HydrophobicContact CG2-CD2 3.83Å; V253-F386 HydrophobicContact CG2-CE2 4.32Å; F256-F386 HydrophobicContact CE2-CB 4.14Å; F256-F386 HydrophobicContact CE2-CD1 4.42Å; F256-F386 HydrophobicContact CE2-CG 4.11Å; W261-F386 AromaticContact CH2-CE1 3.86Å; W261-F386 HydrophobicContact CH2-CE1 3.86Å; W261-F386 HydrophobicContact CH2-CE2 4.44Å; W261-F386 AromaticContact CH2-CZ 3.58Å; W261-F386 HydrophobicContact CH2-CZ 3.58Å; W261-F386 AromaticContact CZ3-CE1 3.61Å; W261-F386 HydrophobicContact CZ3-CE1 3.61Å; W261-F386 AromaticContact CZ3-CZ 3.7Å; W261-F386 HydrophobicContact CZ3-CZ 3.7Å; F264-F386 AromaticContact CD2-CD1 3.52Å; F264-F386 HydrophobicContact CD2-CD1 3.52Å; F264-F386 AromaticContact CD2-CE1 3.6Å; F264-F386 HydrophobicContact CD2-CE1 3.6Å; F264-F386 AromaticContact CE2-CD1 3.26Å; F264-F386 HydrophobicContact CE2-CD1 3.26Å; F264-F386 AromaticContact CE2-CE1 3.72Å; F264-F386 HydrophobicContact CE2-CE1 3.72Å; F264-F386 HydrophobicContact CE2-CG 4.17Å; F264-F386 HydrophobicContact CG-CD1 4.27Å; F264-F386 HydrophobicContact CG-CE1 4.46Å; F264-F386 HydrophobicContact CZ-CB 4.4Å; F264-F386 AromaticContact CZ-CD1 3.82Å; F264-F386 HydrophobicContact CZ-CD1 3.82Å; F264-F386 HydrophobicContact CZ-CG 4.5Å; T382-F386 WeakPolarHBondContact O-CB 3.2Å; T382-F386 PolarHBondContact O-N 3.48Å; A383-F386 PolarHBondContact O-N 3.16Å; Y384-F386 VanDerWaalsContact C-N 3.31Å; Y384-F386 PolarHBondContact O-N 2.96Å; F386-Q388 VanDerWaalsContact C-N 3.31Å; F386-Q388 PolarHBondContact O-N 3.12Å; F386-S389 PolarHBondContact O-N 3.33Å; F386-I390 HydrophobicContact CD1-CG2 4.44Å; F386-I390 HydrophobicContact CE1-CB 4.34Å; F386-I390 HydrophobicContact CE1-CD1 4.19Å; F386-I390 HydrophobicContact CE1-CG2 4.38Å; F386-I390 WeakPolarHBondContact O-CG2 3.38Å; F386-I390 PolarHBondContact O-N 3.5Å
387	M	92.3	Very high	89.7	Confident	0 Å²	0	34.2 Å²	34.2	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-55.7	-45.3	178.1	-173.8	174.5	171.6	0	0	111.9	I263 F264 C267 L367 W368 V371 A383 Y384 I390 Q391	I263-M387 HydrophobicContact CG2-CE 4.41Å; I263-M387 HydrophobicContact CG2-SD 4.49Å; F264-M387 HydrophobicContact CD1-CB 3.83Å; F264-M387 HydrophobicContact CD1-CG 3.91Å; F264-M387 HydrophobicContact CE1-CB 3.64Å; F264-M387 HydrophobicContact CE1-CG 4.14Å; C267-M387 HydrophobicContact CB-CE 3.73Å; C267-M387 HydrophobicContact CB-CG 4.31Å; C267-M387 WeakPolarHBondContact SG-CE 3.37Å; L367-M387 HydrophobicContact CD2-CE 4.03Å; L367-M387 HydrophobicContact CG-CE 4.1Å; W368-M387 HydrophobicContact CD2-CE 3.69Å; W368-M387 HydrophobicContact CD2-SD 4.25Å; W368-M387 HydrophobicContact CE3-CE 4.01Å; W368-M387 HydrophobicContact CE3-SD 3.95Å; W368-M387 HydrophobicContact CG-CE 4.06Å; W368-M387 HydrophobicContact CH2-CE 4.4Å; W368-M387 HydrophobicContact CH2-CG 4.45Å; W368-M387 HydrophobicContact CH2-SD 4.48Å; W368-M387 HydrophobicContact CZ2-CE 4.11Å; W368-M387 HydrophobicContact CZ3-CE 4.36Å; W368-M387 HydrophobicContact CZ3-CG 4.43Å; W368-M387 HydrophobicContact CZ3-SD 4.08Å; V371-M387 HydrophobicContact CG2-SD 3.48Å; V371-M387 WeakPolarHBondContact CG2-SD 3.5Å; A383-M387 WeakPolarHBondContact O-CB 3.45Å; A383-M387 PolarHBondContact O-N 3.26Å; Y384-M387 PolarHBondContact O-N 3.44Å; M387-I390 WeakPolarHBondContact O-CG2 3.45Å; M387-Q391 VanDerWaalsContact O-CB 3.3Å; M387-Q391 WeakPolarHBondContact O-CB 3.38Å; M387-Q391 PolarHBondContact O-N 2.73Å; M387-Q391 VanDerWaalsContact O-N 3.1Å
388	Q	91.9	Very high	90.6	Very high	27 Å²	27	28.2 Å²	28.2	13%	0.126	15%	0.15	C	C	.	.	H	α-helix	trans	-73.1	-33.4	179.9	-161.8	172.8	-1.3	0	0	112.3	C90 E145 W368 Y384 F386 N392	C90-Q388 HydrophobicContact CB-CB 4.03Å; C90-Q388 HydrophobicContact CB-CG 4.26Å; C90-Q388 VanDerWaalsContact SG-CG 3.51Å; E145-Q388 PolarHBondContact OE2-NE2 3.48Å; W368-Q388 HydrophobicContact CH2-CB 4.45Å; Y384-Q388 PolarHBondContact O-N 3.37Å; F386-Q388 VanDerWaalsContact C-N 3.31Å; F386-Q388 PolarHBondContact O-N 3.12Å; Q388-N392 WeakPolarHBondContact O-CB 3.47Å; Q388-N392 PolarHBondContact O-N 3.25Å; Q388-N392 PolarHBondContact O-ND2 2.95Å; Q388-N392 VanDerWaalsContact O-ND2 3.12Å
389	S	93.3	Very high	91.5	Very high	4 Å²	4	22.9 Å²	22.9	3%	0.028	13%	0.126	C	C	.	.	H	α-helix	trans	-66.7	-47.5	176.2	-60.5	0	0	0	0	112.1	V87 C90 F91 G385 F386 Q391 N392 L393	V87-S389 WeakPolarHBondContact O-CB 3.33Å; V87-S389 PolarHBondContact O-OG 2.73Å; C90-S389 VanDerWaalsContact CB-OG 3.26Å; C90-S389 WeakPolarHBondContact CB-OG 3.28Å; F91-S389 WeakPolarHBondContact CD2-OG 3.29Å; F91-S389 WeakPolarHBondContact CE2-OG 3.14Å; G385-S389 VanDerWaalsContact O-CB 3.31Å; G385-S389 WeakPolarHBondContact O-CB 3.37Å; G385-S389 PolarHBondContact O-N 3.25Å; G385-S389 PolarHBondContact O-OG 2.99Å; F386-S389 PolarHBondContact O-N 3.33Å; S389-Q391 VanDerWaalsContact C-N 3.33Å; S389-N392 PolarHBondContact O-N 2.91Å; S389-L393 PolarHBondContact O-N 3.21Å
390	I	94.5	Very high	92.3	Very high	48 Å²	48	24.5 Å²	24.5	25%	0.246	13%	0.134	C	C	.	.	H	α-helix	trans	-69.2	-34.1	178.9	-161.3	176.5	0	0	0	111.4	F264 V268 F386 M387 L393 G394	F264-I390 HydrophobicContact CB-CG2 4.36Å; V268-I390 HydrophobicContact CG2-CB 4.18Å; V268-I390 HydrophobicContact CG2-CD1 4.32Å; V268-I390 HydrophobicContact CG2-CG1 3.86Å; V268-I390 HydrophobicContact CG2-CG2 3.68Å; F386-I390 HydrophobicContact CD1-CG2 4.44Å; F386-I390 HydrophobicContact CE1-CB 4.34Å; F386-I390 HydrophobicContact CE1-CD1 4.19Å; F386-I390 HydrophobicContact CE1-CG2 4.38Å; F386-I390 WeakPolarHBondContact O-CG2 3.38Å; F386-I390 PolarHBondContact O-N 3.5Å; M387-I390 WeakPolarHBondContact O-CG2 3.45Å; I390-L393 PolarHBondContact O-N 3.19Å; I390-G394 PolarHBondContact O-N 3.26Å
391	Q	95.6	Very high	93.1	Very high	16 Å²	16	24.1 Å²	24.1	8%	0.075	14%	0.137	C	C	.	.	H	α-helix	trans	-59.8	-49.1	170.7	-178.3	-171.5	0.1	0	0	111	Y271 M387 S389 L393 G394 L395	Y271-Q391 HydrophobicContact CD2-CG 4.22Å; Y271-Q391 VanDerWaalsContact CD2-NE2 3.28Å; M387-Q391 VanDerWaalsContact O-CB 3.3Å; M387-Q391 WeakPolarHBondContact O-CB 3.38Å; M387-Q391 PolarHBondContact O-N 2.73Å; M387-Q391 VanDerWaalsContact O-N 3.1Å; S389-Q391 VanDerWaalsContact C-N 3.33Å; Q391-L393 VanDerWaalsContact C-N 3.34Å; Q391-L393 PolarHBondContact O-N 3.39Å; Q391-G394 PolarHBondContact O-N 3.47Å; Q391-L395 HydrophobicContact CG-CD1 4.3Å; Q391-L395 WeakPolarHBondContact O-CG 3.31Å; Q391-L395 PolarHBondContact O-N 2.91Å
392	N	95.9	Very high	93.9	Very high	1 Å²	1	22.9 Å²	22.9	1%	0.005	12%	0.124	C	C	.	.	H	α-helix	trans	-64.9	-36.6	178	-91.6	-75.2	0	0	0	112.6	S83 N86 V87 E145 Q388 S389 G394 L395 A396	S83-N392 WeakPolarHBondContact CB-O 3.49Å; S83-N392 WeakPolarHBondContact CB-OD1 3.4Å; S83-N392 PolarHBondContact OG-OD1 3.34Å; N86-N392 HydrophobicContact CB-CB 3.88Å; N86-N392 VanDerWaalsContact CB-CG 3.43Å; V87-N392 HydrophobicContact CG2-CB 4.47Å; E145-N392 PolarHBondContact OE1-ND2 3.37Å; Q388-N392 WeakPolarHBondContact O-CB 3.47Å; Q388-N392 PolarHBondContact O-N 3.25Å; Q388-N392 PolarHBondContact O-ND2 2.95Å; Q388-N392 VanDerWaalsContact O-ND2 3.12Å; S389-N392 PolarHBondContact O-N 2.91Å; N392-G394 VanDerWaalsContact C-N 3.34Å; N392-G394 PolarHBondContact O-N 2.87Å; N392-L395 PolarHBondContact O-N 3.43Å; N392-A396 WeakPolarHBondContact O-CB 3.3Å; N392-A396 PolarHBondContact O-N 3.39Å
393	L	97.2	Very high	94.4	Very high	67 Å²	67	22.8 Å²	22.8	35%	0.351	12%	0.123	S	C	.	.	H	α-helix	trans	-61	-45.8	172.3	178.7	62.2	0	0	0	111	W84 V87 S389 I390 Q391 A396 V397	W84-L393 HydrophobicContact CH2-CD1 4.25Å; W84-L393 HydrophobicContact CZ3-CD1 3.84Å; V87-L393 HydrophobicContact CG1-CB 4.25Å; V87-L393 HydrophobicContact CG1-CD1 4.4Å; V87-L393 HydrophobicContact CG2-CB 3.94Å; V87-L393 HydrophobicContact CG2-CD1 4.28Å; S389-L393 PolarHBondContact O-N 3.21Å; I390-L393 PolarHBondContact O-N 3.19Å; Q391-L393 VanDerWaalsContact C-N 3.34Å; Q391-L393 PolarHBondContact O-N 3.39Å; L393-A396 PolarHBondContact O-N 3.09Å; L393-V397 HydrophobicContact CD1-CG2 4.21Å; L393-V397 WeakPolarHBondContact O-CG2 3.33Å; L393-V397 PolarHBondContact O-N 3.48Å
394	G	97.1	Very high	94.8	Very high	10 Å²	10	25.9 Å²	25.9	10%	0.103	14%	0.142	C	C	.	.	H	α-helix	trans	-57.9	-47.9	174.1	0	0	0	0	0	112	V272 I390 Q391 N392 A396 V397 I398	V272-G394 VanDerWaalsContact CG1-C 3.42Å; I390-G394 PolarHBondContact O-N 3.26Å; Q391-G394 PolarHBondContact O-N 3.47Å; N392-G394 VanDerWaalsContact C-N 3.34Å; N392-G394 PolarHBondContact O-N 2.87Å; G394-A396 PolarHBondContact O-N 2.88Å; G394-V397 PolarHBondContact O-N 3.43Å; G394-I398 WeakPolarHBondContact O-CB 3.2Å; G394-I398 WeakPolarHBondContact O-CG1 3.27Å; G394-I398 PolarHBondContact O-N 3.2Å
395	L	97.1	Very high	95.3	Very high	11 Å²	11	24 Å²	24	6%	0.058	14%	0.136	C	C	.	.	H	α-helix	trans	-61.4	-41.9	178.2	-70.7	174.5	0	0	0	112.2	V272 F275 P276 Q391 N392 A399	V272-L395 HydrophobicContact CG1-CD2 4.2Å; F275-L395 HydrophobicContact CB-CD2 3.82Å; F275-L395 HydrophobicContact CD2-CD1 4.18Å; F275-L395 HydrophobicContact CD2-CD2 3.99Å; F275-L395 HydrophobicContact CG-CD2 4.36Å; P276-L395 HydrophobicContact CG-CD2 4.23Å; Q391-L395 HydrophobicContact CG-CD1 4.3Å; Q391-L395 WeakPolarHBondContact O-CG 3.31Å; Q391-L395 PolarHBondContact O-N 2.91Å; N392-L395 PolarHBondContact O-N 3.43Å; L395-A399 WeakPolarHBondContact O-CB 3.46Å; L395-A399 PolarHBondContact O-N 3.44Å
396	A	96.8	Very high	95.7	Very high	0 Å²	0	24.3 Å²	24.3	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-62.9	-50.3	178.4	0	0	0	0	0	112	W84 N392 L393 G394 I400	W84-A396 HydrophobicContact CD2-CB 3.97Å; W84-A396 HydrophobicContact CE3-CB 4.35Å; W84-A396 HydrophobicContact CG-CB 4.36Å; W84-A396 HydrophobicContact CZ2-CB 4.16Å; N392-A396 WeakPolarHBondContact O-CB 3.3Å; N392-A396 PolarHBondContact O-N 3.39Å; L393-A396 PolarHBondContact O-N 3.09Å; G394-A396 PolarHBondContact O-N 2.88Å; A396-I400 WeakPolarHBondContact O-CG1 3.42Å
397	V	97.7	Very high	95.8	Very high	75 Å²	75	26 Å²	26	46%	0.455	15%	0.148	S	C	.	.	H	α-helix	trans	-68.1	-44.6	-178.5	174.3	0	0	0	0	111.3	W84 L393 G394 I400 A401	W84-V397 HydrophobicContact CH2-CG2 4.43Å; L393-V397 HydrophobicContact CD1-CG2 4.21Å; L393-V397 WeakPolarHBondContact O-CG2 3.33Å; L393-V397 PolarHBondContact O-N 3.48Å; G394-V397 PolarHBondContact O-N 3.43Å; V397-I400 PolarHBondContact O-N 3.03Å; V397-A401 PolarHBondContact O-N 2.97Å; V397-A401 VanDerWaalsContact O-N 3.12Å
398	I	97.1	Very high	96	Very high	26 Å²	26	32 Å²	32	13%	0.133	18%	0.179	C	C	.	.	H	α-helix	trans	-72.2	-33.9	-176.1	-62.9	-72.3	0	0	0	111.2	V272 P276 G394 I400 A401 V402 F417	V272-I398 HydrophobicContact CB-CB 3.99Å; V272-I398 HydrophobicContact CB-CG1 3.86Å; V272-I398 HydrophobicContact CB-CG2 3.98Å; V272-I398 HydrophobicContact CG1-CB 4.2Å; V272-I398 HydrophobicContact CG1-CG1 3.91Å; V272-I398 HydrophobicContact CG2-CG1 4.17Å; P276-I398 HydrophobicContact CG-CG2 4.18Å; G394-I398 WeakPolarHBondContact O-CB 3.2Å; G394-I398 WeakPolarHBondContact O-CG1 3.27Å; G394-I398 PolarHBondContact O-N 3.2Å; I398-I400 VanDerWaalsContact C-N 3.28Å; I398-I400 PolarHBondContact O-N 3Å; I398-A401 PolarHBondContact O-N 3.11Å; I398-V402 HydrophobicContact CG2-CG2 3.86Å; I398-V402 WeakPolarHBondContact O-CB 3.46Å; I398-V402 WeakPolarHBondContact O-CG2 3.46Å; I398-V402 PolarHBondContact O-N 3.02Å; I398-F417 HydrophobicContact CD1-CE1 4.13Å; I398-F417 HydrophobicContact CD1-CZ 3.64Å; I398-F417 HydrophobicContact CG2-CE1 3.92Å; I398-F417 HydrophobicContact CG2-CZ 4.44Å
399	A	96.3	Very high	96.2	Very high	1 Å²	1	39.1 Å²	39.1	1%	0.008	20%	0.204	C	C	.	.	H	α-helix	trans	-56.1	-45	173.1	0	0	0	0	0	111.6	M76 A80 L395 V402 G403	M76-A399 VanDerWaalsContact CB-O 3.22Å; M76-A399 WeakPolarHBondContact CB-O 3.38Å; M76-A399 HydrophobicContact CE-CB 4.41Å; A80-A399 HydrophobicContact CB-CB 4.39Å; L395-A399 WeakPolarHBondContact O-CB 3.46Å; L395-A399 PolarHBondContact O-N 3.44Å; A399-V402 PolarHBondContact O-N 3.06Å; A399-G403 PolarHBondContact O-N 3.11Å; A399-G403 VanDerWaalsContact O-N 3.12Å
400	I	96.5	Very high	96.3	Very high	54 Å²	54	40.1 Å²	40.1	28%	0.277	22%	0.216	S	C	.	.	H	α-helix	trans	-61.3	-48.6	176	-59	171.2	0	0	0	110.5	A80 A396 V397 I398 V402 G403 V404	A80-I400 HydrophobicContact CB-CD1 4.2Å; A80-I400 HydrophobicContact CB-CG1 3.86Å; A396-I400 WeakPolarHBondContact O-CG1 3.42Å; V397-I400 PolarHBondContact O-N 3.03Å; I398-I400 VanDerWaalsContact C-N 3.28Å; I398-I400 PolarHBondContact O-N 3Å; I400-V402 VanDerWaalsContact C-N 3.34Å; I400-V402 PolarHBondContact O-N 3.48Å; I400-G403 PolarHBondContact O-N 2.96Å; I400-V404 WeakPolarHBondContact O-CG2 3.39Å; I400-V404 PolarHBondContact O-N 3.26Å
401	A	97.2	Very high	96.3	Very high	31 Å²	31	39.6 Å²	39.6	26%	0.256	21%	0.211	S	C	.	.	H	α-helix	trans	-60.2	-42.7	179.3	0	0	0	0	0	112.2	V397 I398 G403 V404 I405	V397-A401 PolarHBondContact O-N 2.97Å; V397-A401 VanDerWaalsContact O-N 3.12Å; I398-A401 PolarHBondContact O-N 3.11Å; A401-G403 PolarHBondContact O-N 3.06Å; A401-V404 PolarHBondContact O-N 3.18Å; A401-I405 WeakPolarHBondContact O-CB 3.47Å; A401-I405 WeakPolarHBondContact O-CD1 3.41Å; A401-I405 WeakPolarHBondContact O-CG1 3.09Å; A401-I405 PolarHBondContact O-N 3.3Å
402	V	96.6	Very high	96.3	Very high	0 Å²	0	43.5 Å²	43.5	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-59.9	-47.4	178.7	163.7	0	0	0	0	111.1	M76 P276 Q280 I398 A399 I400 V404 I405 V406 L414 F417 F418	M76-V402 HydrophobicContact CE-CB 3.96Å; M76-V402 HydrophobicContact CE-CG1 3.52Å; P276-V402 HydrophobicContact CB-CG2 3.93Å; Q280-V402 HydrophobicContact CG-CG1 3.82Å; I398-V402 HydrophobicContact CG2-CG2 3.86Å; I398-V402 WeakPolarHBondContact O-CB 3.46Å; I398-V402 WeakPolarHBondContact O-CG2 3.46Å; I398-V402 PolarHBondContact O-N 3.02Å; A399-V402 PolarHBondContact O-N 3.06Å; I400-V402 VanDerWaalsContact C-N 3.34Å; I400-V402 PolarHBondContact O-N 3.48Å; V402-V404 PolarHBondContact O-N 3.49Å; V402-I405 PolarHBondContact O-N 2.91Å; V402-V406 WeakPolarHBondContact O-CG2 3.47Å; V402-V406 PolarHBondContact O-N 3.25Å; V402-L414 HydrophobicContact CB-CD1 3.94Å; V402-L414 HydrophobicContact CG1-CD1 3.54Å; V402-L414 HydrophobicContact CG1-CD2 4.09Å; V402-L414 HydrophobicContact CG1-CG 4.48Å; V402-L414 HydrophobicContact CG2-CD1 3.66Å; V402-F417 HydrophobicContact CG2-CE1 4.36Å; V402-F418 HydrophobicContact CG1-CZ 4.37Å; V402-F418 HydrophobicContact CG2-CE1 3.63Å; V402-F418 HydrophobicContact CG2-CZ 3.65Å
403	G	94.8	Very high	96.3	Very high	0 Å²	0	46.1 Å²	46.1	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-60.8	-44.5	179.1	0	0	0	0	0	112.4	A399 I400 A401 V406 D407	A399-G403 PolarHBondContact O-N 3.11Å; A399-G403 VanDerWaalsContact O-N 3.12Å; I400-G403 PolarHBondContact O-N 2.96Å; A401-G403 PolarHBondContact O-N 3.06Å; G403-V406 PolarHBondContact O-N 3.32Å; G403-D407 PolarHBondContact O-N 3.27Å; G403-D407 VanDerWaalsContact O-N 3.09Å
404	V	96.7	Very high	96.3	Very high	64 Å²	64	43 Å²	43	39%	0.388	23%	0.231	S	C	.	.	H	α-helix	trans	-64	-42.3	175.8	174.6	0	0	0	0	112.2	A73 I400 A401 V402 V406 D407 I408	A73-V404 HydrophobicContact CB-CG2 4.16Å; I400-V404 WeakPolarHBondContact O-CG2 3.39Å; I400-V404 PolarHBondContact O-N 3.26Å; A401-V404 PolarHBondContact O-N 3.18Å; V402-V404 PolarHBondContact O-N 3.49Å; V404-V406 VanDerWaalsContact C-N 3.34Å; V404-V406 PolarHBondContact O-N 3Å; V404-D407 PolarHBondContact O-N 2.91Å; V404-I408 HydrophobicContact CG1-CD1 3.61Å; V404-I408 HydrophobicContact CG1-CG1 4.44Å; V404-I408 WeakPolarHBondContact O-CG1 3.39Å; V404-I408 PolarHBondContact O-N 3Å; V404-I408 VanDerWaalsContact O-N 3.1Å
405	I	97.6	Very high	96.3	Very high	30 Å²	30	42.5 Å²	42.5	15%	0.154	23%	0.226	C	C	.	.	H	α-helix	trans	-61.8	-44.1	178.3	-72	164.1	0	0	0	110.4	A401 V402 R409 G410 V413 L414 F417	A401-I405 WeakPolarHBondContact O-CB 3.47Å; A401-I405 WeakPolarHBondContact O-CD1 3.41Å; A401-I405 WeakPolarHBondContact O-CG1 3.09Å; A401-I405 PolarHBondContact O-N 3.3Å; V402-I405 PolarHBondContact O-N 2.91Å; I405-R409 HydrophobicContact CG2-CB 4.47Å; I405-R409 CarbonylContact O-C 3.59Å; I405-R409 WeakPolarHBondContact O-CA 3.33Å; I405-R409 VanDerWaalsContact O-CB 3.32Å; I405-R409 WeakPolarHBondContact O-CB 3.4Å; I405-R409 PolarHBondContact O-N 3.37Å; I405-G410 PolarHBondContact O-N 2.74Å; I405-V413 HydrophobicContact CG2-CB 4.26Å; I405-V413 HydrophobicContact CG2-CG1 3.97Å; I405-L414 HydrophobicContact CG2-CB 4.14Å; I405-F417 HydrophobicContact CD1-CB 4.15Å; I405-F417 HydrophobicContact CD1-CD1 3.88Å; I405-F417 HydrophobicContact CD1-CD2 3.88Å; I405-F417 HydrophobicContact CD1-CE1 4.2Å; I405-F417 HydrophobicContact CD1-CE2 4.2Å; I405-F417 HydrophobicContact CD1-CG 3.69Å; I405-F417 HydrophobicContact CD1-CZ 4.34Å
406	V	96.1	Very high	96.4	Very high	13 Å²	13	44.9 Å²	44.9	8%	0.079	24%	0.241	C	C	.	.	H	α-helix	trans	-63.7	-48.2	179.5	173.4	0	0	0	0	110.9	T72 V402 G403 V404 I408 G410 Y411 L414	T72-V406 HydrophobicContact CG2-CB 3.96Å; T72-V406 HydrophobicContact CG2-CG1 3.89Å; T72-V406 HydrophobicContact CG2-CG2 4.49Å; V402-V406 WeakPolarHBondContact O-CG2 3.47Å; V402-V406 PolarHBondContact O-N 3.25Å; G403-V406 PolarHBondContact O-N 3.32Å; V404-V406 VanDerWaalsContact C-N 3.34Å; V404-V406 PolarHBondContact O-N 3Å; V406-I408 VanDerWaalsContact C-N 3.31Å; V406-I408 PolarHBondContact O-N 3.22Å; V406-G410 VanDerWaalsContact O-CA 3.29Å; V406-G410 WeakPolarHBondContact O-CA 3.4Å; V406-G410 PolarHBondContact O-N 3.39Å; V406-Y411 HydrophobicContact CG1-CE1 4Å; V406-Y411 HydrophobicContact CG1-CE2 4.06Å; V406-Y411 HydrophobicContact CG2-CD1 4.23Å; V406-Y411 HydrophobicContact CG2-CE1 4.07Å; V406-L414 HydrophobicContact CG2-CB 4.18Å; V406-L414 HydrophobicContact CG2-CD1 4.46Å; V406-L414 HydrophobicContact CG2-CD2 3.58Å; V406-L414 HydrophobicContact CG2-CG 4.27Å
407	D	94.8	Very high	96.4	Very high	69 Å²	69	47.5 Å²	47.5	37%	0.369	25%	0.253	S	S	.	.	H	α-helix	trans	-63.5	-34.8	-177.3	-74.1	-21.1	0	0	0	112.7	N71 T72 A73 G403 V404	N71-D407 PolarHBondContact OD1-OD2 3.35Å; T72-D407 WeakPolarHBondContact CB-OD1 3.23Å; T72-D407 PolarHBondContact N-OD1 3.49Å; T72-D407 VanDerWaalsContact N-OD1 3.12Å; T72-D407 PolarHBondContact N-OD2 2.78Å; T72-D407 PolarHBondContact OG1-OD1 3.33Å; A73-D407 WeakPolarHBondContact CB-OD2 3.45Å; A73-D407 PolarHBondContact N-OD2 3.47Å; G403-D407 PolarHBondContact O-N 3.27Å; G403-D407 VanDerWaalsContact O-N 3.09Å; V404-D407 PolarHBondContact O-N 2.91Å
408	I	96	Very high	96.5	Very high	126 Å²	126	44 Å²	44	65%	0.646	23%	0.231	S	C	*	.	H	α-helix	trans	-95.7	-37.1	-175.4	-58.1	175.1	0	0	0	112.7	V404 V406	V404-I408 HydrophobicContact CG1-CD1 3.61Å; V404-I408 HydrophobicContact CG1-CG1 4.44Å; V404-I408 WeakPolarHBondContact O-CG1 3.39Å; V404-I408 PolarHBondContact O-N 3Å; V404-I408 VanDerWaalsContact O-N 3.1Å; V406-I408 VanDerWaalsContact C-N 3.31Å; V406-I408 PolarHBondContact O-N 3.22Å
409	R	95.7	Very high	96.5	Very high	175 Å²	175	43.3 Å²	43.3	66%	0.66	23%	0.229	S	C	*	.	H	α-helix	trans	-125.2	-8.7	-164.9	-53.7	-70	-84.2	171	-6.3	113.4	I405 V413	I405-R409 HydrophobicContact CG2-CB 4.47Å; I405-R409 CarbonylContact O-C 3.59Å; I405-R409 WeakPolarHBondContact O-CA 3.33Å; I405-R409 VanDerWaalsContact O-CB 3.32Å; I405-R409 WeakPolarHBondContact O-CB 3.4Å; I405-R409 PolarHBondContact O-N 3.37Å; R409-V413 HydrophobicContact CB-CB 3.72Å; R409-V413 HydrophobicContact CB-CG1 3.85Å; R409-V413 HydrophobicContact CB-CG2 3.86Å; R409-V413 HydrophobicContact CG-CG1 4.39Å
410	G	94.6	Very high	96.6	Very high	26 Å²	26	45.6 Å²	45.6	27%	0.268	25%	0.248	S	C	.	.	H	α-helix	trans	73.5	179.7	177.8	0	0	0	0	0	114.8	I405 V406 L412 V413 L414	I405-G410 PolarHBondContact O-N 2.74Å; V406-G410 VanDerWaalsContact O-CA 3.29Å; V406-G410 WeakPolarHBondContact O-CA 3.4Å; V406-G410 PolarHBondContact O-N 3.39Å; G410-L412 PolarHBondContact O-N 2.79Å; G410-V413 PolarHBondContact O-N 3.35Å; G410-L414 PolarHBondContact O-N 3.43Å
411	Y	94.4	Very high	96.7	Very high	37 Å²	37	43.3 Å²	43.3	15%	0.145	24%	0.237	C	C	.	.	H	α-helix	trans	-69.2	-27.2	-169.3	-74.2	-72.9	0	0	0	115.7	V283 F284 E287 V406 L414 E415	V283-Y411 WeakPolarHBondContact CB-OH 3.37Å; V283-Y411 HydrophobicContact CG1-CE2 4.23Å; V283-Y411 WeakPolarHBondContact CG1-OH 3.39Å; F284-Y411 HydrophobicContact CB-CD1 3.84Å; F284-Y411 HydrophobicContact CB-CE1 3.88Å; F284-Y411 HydrophobicContact CB-CG 4.5Å; F284-Y411 AromaticContact CD2-CD1 3.62Å; F284-Y411 HydrophobicContact CD2-CD1 3.62Å; F284-Y411 HydrophobicContact CD2-CE1 4.49Å; F284-Y411 AromaticContact CD2-CG 3.79Å; F284-Y411 HydrophobicContact CD2-CG 3.79Å; F284-Y411 HydrophobicContact CG-CD1 4.24Å; E287-Y411 HydrophobicContact CB-CD2 4.41Å; E287-Y411 HydrophobicContact CB-CE2 4.35Å; E287-Y411 HydrophobicContact CG-CE2 4.14Å; V406-Y411 HydrophobicContact CG1-CE1 4Å; V406-Y411 HydrophobicContact CG1-CE2 4.06Å; V406-Y411 HydrophobicContact CG2-CD1 4.23Å; V406-Y411 HydrophobicContact CG2-CE1 4.07Å; Y411-L414 HydrophobicContact CD1-CD2 4.04Å; Y411-L414 HydrophobicContact CE1-CD2 4.45Å; Y411-L414 WeakPolarHBondContact O-CB 3.49Å; Y411-L414 PolarHBondContact O-N 2.93Å; Y411-E415 PolarHBondContact O-N 3.22Å
412	L	95.4	Very high	96.8	Very high	98 Å²	98	41.9 Å²	41.9	51%	0.513	22%	0.224	S	C	.	.	H	α-helix	trans	-65.2	-45.1	176.9	178	63.1	0	0	0	110.9	A343 F344 G410 L414 E415 V416	A343-L412 HydrophobicContact CB-CD1 4.45Å; A343-L412 VanDerWaalsContact O-CD1 3.25Å; A343-L412 WeakPolarHBondContact O-CD1 3.27Å; F344-L412 HydrophobicContact CD1-CD1 4.44Å; F344-L412 HydrophobicContact CE1-CD1 4.41Å; G410-L412 PolarHBondContact O-N 2.79Å; L412-L414 VanDerWaalsContact C-N 3.27Å; L412-L414 PolarHBondContact O-N 3.37Å; L412-E415 PolarHBondContact O-N 2.89Å; L412-V416 WeakPolarHBondContact O-CG2 3.28Å; L412-V416 PolarHBondContact O-N 3.06Å
413	V	97.1	Very high	96.9	Very high	55 Å²	55	44.3 Å²	44.3	33%	0.333	24%	0.241	S	C	.	.	H	α-helix	trans	-67.8	-33	178.2	178.9	0	0	0	0	110.6	I405 R409 G410 V416 F417	I405-V413 HydrophobicContact CG2-CB 4.26Å; I405-V413 HydrophobicContact CG2-CG1 3.97Å; R409-V413 HydrophobicContact CB-CB 3.72Å; R409-V413 HydrophobicContact CB-CG1 3.85Å; R409-V413 HydrophobicContact CB-CG2 3.86Å; R409-V413 HydrophobicContact CG-CG1 4.39Å; G410-V413 PolarHBondContact O-N 3.35Å; V413-V416 PolarHBondContact O-N 3.09Å; V413-F417 WeakPolarHBondContact O-CB 3.36Å; V413-F417 PolarHBondContact O-N 3.27Å
414	L	96.8	Very high	97	Very high	1 Å²	1	47.2 Å²	47.2	1%	0.005	26%	0.256	C	S	.	.	H	α-helix	trans	-58.5	-50.3	170.8	177.5	64.8	0	0	0	112	Q280 V402 I405 V406 G410 Y411 L412 V416 F417 F418	Q280-L414 HydrophobicContact CB-CD2 4.48Å; V402-L414 HydrophobicContact CB-CD1 3.94Å; V402-L414 HydrophobicContact CG1-CD1 3.54Å; V402-L414 HydrophobicContact CG1-CD2 4.09Å; V402-L414 HydrophobicContact CG1-CG 4.48Å; V402-L414 HydrophobicContact CG2-CD1 3.66Å; I405-L414 HydrophobicContact CG2-CB 4.14Å; V406-L414 HydrophobicContact CG2-CB 4.18Å; V406-L414 HydrophobicContact CG2-CD1 4.46Å; V406-L414 HydrophobicContact CG2-CD2 3.58Å; V406-L414 HydrophobicContact CG2-CG 4.27Å; G410-L414 PolarHBondContact O-N 3.43Å; Y411-L414 HydrophobicContact CD1-CD2 4.04Å; Y411-L414 HydrophobicContact CE1-CD2 4.45Å; Y411-L414 WeakPolarHBondContact O-CB 3.49Å; Y411-L414 PolarHBondContact O-N 2.93Å; L412-L414 VanDerWaalsContact C-N 3.27Å; L412-L414 PolarHBondContact O-N 3.37Å; L414-V416 VanDerWaalsContact C-N 3.32Å; L414-V416 PolarHBondContact O-N 3.35Å; L414-F417 WeakPolarHBondContact O-CB 3.33Å; L414-F417 PolarHBondContact O-N 2.9Å; L414-F417 VanDerWaalsContact O-N 3.13Å; L414-F418 HydrophobicContact CD1-CD2 4.25Å; L414-F418 HydrophobicContact CD1-CE1 4.18Å; L414-F418 HydrophobicContact CD1-CE2 3.59Å; L414-F418 HydrophobicContact CD1-CZ 3.56Å; L414-F418 HydrophobicContact CD2-CE2 3.82Å; L414-F418 HydrophobicContact CD2-CZ 4.32Å; L414-F418 HydrophobicContact CG-CD2 4.04Å; L414-F418 HydrophobicContact CG-CE2 3.5Å; L414-F418 VanDerWaalsContact CG-CE2 3.5Å; L414-F418 HydrophobicContact CG-CZ 4.02Å; L414-F418 PolarHBondContact O-N 3.02Å
415	E	97.8	Very high	97.1	Very high	0 Å²	0	44.2 Å²	44.2	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-63.9	-38	179.5	-73.4	-59.6	124.2	0	0	112.4	F277 F284 H339 A343 Y411 L412 F417 F418 C419	F277-E415 WeakPolarHBondContact CD2-OE1 3.34Å; F277-E415 WeakPolarHBondContact CE2-OE1 3.44Å; F284-E415 HydrophobicContact CE2-CG 3.83Å; F284-E415 HydrophobicContact CZ-CG 4.08Å; H339-E415 IonicContact CE1-OE2 2.66Å; H339-E415 IonicContact CG-OE2 2.83Å; H339-E415 IonicContact ND1-OE1 2.69Å; H339-E415 IonicContact ND1-OE2 3.89Å; H339-E415 PolarHBondContact ND1-OE2 2.7Å; A343-E415 HydrophobicContact CB-CB 3.57Å; A343-E415 HydrophobicContact CB-CG 4.31Å; Y411-E415 PolarHBondContact O-N 3.22Å; L412-E415 PolarHBondContact O-N 2.89Å; E415-F417 VanDerWaalsContact C-N 3.3Å; E415-F417 PolarHBondContact O-N 2.86Å; E415-F418 PolarHBondContact O-N 3.33Å; E415-C419 PolarHBondContact O-N 3.14Å; E415-C419 PolarHBondContact O-SG 3.44Å
416	V	97.9	Very high	97.2	Very high	62 Å²	62	44.6 Å²	44.6	38%	0.376	24%	0.24	S	C	.	.	H	α-helix	trans	-63.2	-38.9	173.9	173.8	0	0	0	0	111.1	F344 L412 V413 L414 C419 A420	F344-V416 HydrophobicContact CE1-CG2 4.1Å; F344-V416 HydrophobicContact CZ-CG2 3.79Å; L412-V416 WeakPolarHBondContact O-CG2 3.28Å; L412-V416 PolarHBondContact O-N 3.06Å; V413-V416 PolarHBondContact O-N 3.09Å; L414-V416 VanDerWaalsContact C-N 3.32Å; L414-V416 PolarHBondContact O-N 3.35Å; V416-C419 WeakPolarHBondContact O-CB 3.28Å; V416-C419 PolarHBondContact O-N 3.49Å; V416-A420 PolarHBondContact O-N 3.17Å
417	F	98.3	Very high	97.3	Very high	55 Å²	55	50 Å²	50	24%	0.241	27%	0.265	C	S	.	.	H	α-helix	trans	-63.7	-41.3	175.2	173	-99.9	0	0	0	112.1	I398 V402 I405 V413 L414 E415 A420 C421	I398-F417 HydrophobicContact CD1-CE1 4.13Å; I398-F417 HydrophobicContact CD1-CZ 3.64Å; I398-F417 HydrophobicContact CG2-CE1 3.92Å; I398-F417 HydrophobicContact CG2-CZ 4.44Å; V402-F417 HydrophobicContact CG2-CE1 4.36Å; I405-F417 HydrophobicContact CD1-CB 4.15Å; I405-F417 HydrophobicContact CD1-CD1 3.88Å; I405-F417 HydrophobicContact CD1-CD2 3.88Å; I405-F417 HydrophobicContact CD1-CE1 4.2Å; I405-F417 HydrophobicContact CD1-CE2 4.2Å; I405-F417 HydrophobicContact CD1-CG 3.69Å; I405-F417 HydrophobicContact CD1-CZ 4.34Å; V413-F417 WeakPolarHBondContact O-CB 3.36Å; V413-F417 PolarHBondContact O-N 3.27Å; L414-F417 WeakPolarHBondContact O-CB 3.33Å; L414-F417 PolarHBondContact O-N 2.9Å; L414-F417 VanDerWaalsContact O-N 3.13Å; E415-F417 VanDerWaalsContact C-N 3.3Å; E415-F417 PolarHBondContact O-N 2.86Å; F417-A420 WeakPolarHBondContact O-CB 3.32Å; F417-A420 PolarHBondContact O-N 2.77Å; F417-C421 PolarHBondContact O-N 3.39Å; F417-C421 PolarHBondContact O-SG 2.96Å; F417-C421 VanDerWaalsContact O-SG 3.33Å
418	F	98.3	Very high	97.4	Very high	0 Å²	0	47 Å²	47	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-64.3	-42.1	172.3	-67.1	-39.4	0	0	0	112.3	V272 A273 P276 F277 H339 V402 L414 E415 A420 C421 I422	V272-F418 WeakPolarHBondContact O-CE1 3.24Å; A273-F418 HydrophobicContact CB-CB 4.12Å; A273-F418 HydrophobicContact CB-CD1 4.11Å; A273-F418 HydrophobicContact CB-CG 4.35Å; P276-F418 HydrophobicContact CB-CE1 4.21Å; P276-F418 HydrophobicContact CB-CZ 4.1Å; F277-F418 HydrophobicContact CB-CD2 4.12Å; F277-F418 HydrophobicContact CB-CE2 3.58Å; F277-F418 HydrophobicContact CB-CZ 3.96Å; F277-F418 HydrophobicContact CD2-CD2 4.26Å; F277-F418 AromaticContact CD2-CE2 3.95Å; F277-F418 HydrophobicContact CD2-CE2 3.95Å; F277-F418 HydrophobicContact CG-CE2 4.23Å; H339-F418 AromaticContact CE1-CD2 3.83Å; V402-F418 HydrophobicContact CG1-CZ 4.37Å; V402-F418 HydrophobicContact CG2-CE1 3.63Å; V402-F418 HydrophobicContact CG2-CZ 3.65Å; L414-F418 HydrophobicContact CD1-CD2 4.25Å; L414-F418 HydrophobicContact CD1-CE1 4.18Å; L414-F418 HydrophobicContact CD1-CE2 3.59Å; L414-F418 HydrophobicContact CD1-CZ 3.56Å; L414-F418 HydrophobicContact CD2-CE2 3.82Å; L414-F418 HydrophobicContact CD2-CZ 4.32Å; L414-F418 HydrophobicContact CG-CD2 4.04Å; L414-F418 HydrophobicContact CG-CE2 3.5Å; L414-F418 VanDerWaalsContact CG-CE2 3.5Å; L414-F418 HydrophobicContact CG-CZ 4.02Å; L414-F418 PolarHBondContact O-N 3.02Å; E415-F418 PolarHBondContact O-N 3.33Å; F418-A420 VanDerWaalsContact C-N 3.27Å; F418-A420 PolarHBondContact O-N 2.88Å; F418-C421 WeakPolarHBondContact O-CB 3.42Å; F418-C421 PolarHBondContact O-N 3.14Å; F418-C421 VanDerWaalsContact O-N 3.15Å; F418-I422 WeakPolarHBondContact O-CG1 3.49Å; F418-I422 PolarHBondContact O-N 3.46Å
419	C	98.4	Very high	97.5	Very high	13 Å²	13	41.1 Å²	41.1	9%	0.088	22%	0.221	C	C	.	.	H	α-helix	trans	-56.4	-42.5	172.8	-66.8	0	0	0	0	111.6	L336 E415 V416 I422 C423	L336-C419 HydrophobicContact CD1-CB 3.97Å; E415-C419 PolarHBondContact O-N 3.14Å; E415-C419 PolarHBondContact O-SG 3.44Å; V416-C419 WeakPolarHBondContact O-CB 3.28Å; V416-C419 PolarHBondContact O-N 3.49Å; C419-I422 PolarHBondContact O-N 3.04Å; C419-C423 PolarHBondContact O-N 2.9Å; C419-C423 PolarHBondContact O-SG 3.2Å
420	A	98.4	Very high	97.6	Very high	49 Å²	49	35.4 Å²	35.4	41%	0.405	21%	0.205	S	C	.	.	H	α-helix	trans	-62.8	-41.9	177.3	0	0	0	0	0	112.4	V416 F417 F418 C423 I424	V416-A420 PolarHBondContact O-N 3.17Å; F417-A420 WeakPolarHBondContact O-CB 3.32Å; F417-A420 PolarHBondContact O-N 2.77Å; F418-A420 VanDerWaalsContact C-N 3.27Å; F418-A420 PolarHBondContact O-N 2.88Å; A420-C423 WeakPolarHBondContact O-CB 3.38Å; A420-C423 PolarHBondContact O-N 3.31Å; A420-I424 WeakPolarHBondContact O-CG1 3.49Å; A420-I424 PolarHBondContact O-N 2.99Å
421	C	98.3	Very high	97.7	Very high	6 Å²	6	35.3 Å²	35.3	4%	0.041	20%	0.204	C	C	.	.	H	α-helix	trans	-60	-47.6	173.7	-64.6	0	0	0	0	111.1	F269 V272 F417 F418 C423 I424 A425	F269-C421 WeakPolarHBondContact CB-O 3.19Å; F269-C421 HydrophobicContact CD1-CB 4.1Å; V272-C421 HydrophobicContact CG2-CB 4.33Å; F417-C421 PolarHBondContact O-N 3.39Å; F417-C421 PolarHBondContact O-SG 2.96Å; F417-C421 VanDerWaalsContact O-SG 3.33Å; F418-C421 WeakPolarHBondContact O-CB 3.42Å; F418-C421 PolarHBondContact O-N 3.14Å; F418-C421 VanDerWaalsContact O-N 3.15Å; C421-C423 VanDerWaalsContact C-N 3.3Å; C421-C423 PolarHBondContact O-N 2.93Å; C421-I424 WeakPolarHBondContact O-CB 3.48Å; C421-I424 PolarHBondContact O-N 3.41Å; C421-A425 PolarHBondContact O-N 3.02Å; C421-A425 VanDerWaalsContact O-N 3.08Å
422	I	98.5	Very high	97.8	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-64.5	-33.5	178.9	-63.5	-54.4	0	0	0	112.3	Y270 A273 V332 T335 L336 F418 C419 I424 A425 L426	Y270-I422 HydrophobicContact CD2-CD1 4.01Å; A273-I422 HydrophobicContact CB-CD1 3.47Å; A273-I422 VanDerWaalsContact CB-CD1 3.47Å; A273-I422 HydrophobicContact CB-CG1 3.72Å; V332-I422 HydrophobicContact CG1-CG2 3.84Å; V332-I422 WeakPolarHBondContact O-CG2 3.21Å; T335-I422 HydrophobicContact CG2-CD1 3.78Å; T335-I422 HydrophobicContact CG2-CG1 4.02Å; L336-I422 HydrophobicContact CB-CG2 3.65Å; L336-I422 HydrophobicContact CD1-CB 4.26Å; L336-I422 HydrophobicContact CD1-CG2 4.1Å; L336-I422 HydrophobicContact CG-CG2 4.37Å; F418-I422 WeakPolarHBondContact O-CG1 3.49Å; F418-I422 PolarHBondContact O-N 3.46Å; C419-I422 PolarHBondContact O-N 3.04Å; I422-I424 VanDerWaalsContact C-N 3.31Å; I422-I424 PolarHBondContact O-N 2.82Å; I422-A425 WeakPolarHBondContact O-CB 3.43Å; I422-A425 PolarHBondContact O-N 2.96Å; I422-L426 WeakPolarHBondContact O-CB 3.35Å; I422-L426 PolarHBondContact O-N 3.24Å
423	C	98.5	Very high	97.8	Very high	52 Å²	52	34.6 Å²	34.6	35%	0.351	20%	0.195	S	C	.	.	H	α-helix	trans	-62.9	-36.3	171.8	-73.4	0	0	0	0	112.4	C419 A420 C421 L426 M427	C419-C423 PolarHBondContact O-N 2.9Å; C419-C423 PolarHBondContact O-SG 3.2Å; A420-C423 WeakPolarHBondContact O-CB 3.38Å; A420-C423 PolarHBondContact O-N 3.31Å; C421-C423 VanDerWaalsContact C-N 3.3Å; C421-C423 PolarHBondContact O-N 2.93Å; C423-L426 WeakPolarHBondContact O-CB 3.3Å; C423-L426 PolarHBondContact O-N 3.14Å; C423-M427 WeakPolarHBondContact O-CG 3.33Å; C423-M427 PolarHBondContact O-N 2.69Å
424	I	98.5	Very high	97.7	Very high	61 Å²	61	37.4 Å²	37.4	31%	0.313	20%	0.203	S	C	.	.	H	α-helix	trans	-65.5	-44.5	173.7	-62.6	166	0	0	0	110.4	I265 F269 A420 C421 I422 L426 M427 A428	I265-I424 HydrophobicContact CG2-CG2 4.2Å; F269-I424 HydrophobicContact CB-CB 4.46Å; F269-I424 HydrophobicContact CB-CG2 4.49Å; F269-I424 HydrophobicContact CD1-CB 3.98Å; F269-I424 HydrophobicContact CD1-CD1 3.89Å; F269-I424 HydrophobicContact CD1-CG2 4.05Å; F269-I424 HydrophobicContact CD2-CB 4.29Å; F269-I424 HydrophobicContact CD2-CG2 3.54Å; F269-I424 HydrophobicContact CE1-CB 4.28Å; F269-I424 HydrophobicContact CE1-CD1 3.47Å; F269-I424 VanDerWaalsContact CE1-CD1 3.47Å; F269-I424 HydrophobicContact CE1-CG1 4.48Å; F269-I424 HydrophobicContact CE1-CG2 4.12Å; F269-I424 HydrophobicContact CE2-CG2 3.62Å; F269-I424 HydrophobicContact CG-CB 3.98Å; F269-I424 HydrophobicContact CG-CG2 3.76Å; F269-I424 HydrophobicContact CZ-CD1 3.94Å; F269-I424 HydrophobicContact CZ-CG2 3.91Å; A420-I424 WeakPolarHBondContact O-CG1 3.49Å; A420-I424 PolarHBondContact O-N 2.99Å; C421-I424 WeakPolarHBondContact O-CB 3.48Å; C421-I424 PolarHBondContact O-N 3.41Å; I422-I424 VanDerWaalsContact C-N 3.31Å; I422-I424 PolarHBondContact O-N 2.82Å; I424-L426 VanDerWaalsContact C-N 3.3Å; I424-L426 PolarHBondContact O-N 3.01Å; I424-M427 HydrophobicContact CB-CE 4.35Å; I424-M427 HydrophobicContact CG1-CE 4Å; I424-M427 PolarHBondContact O-N 3.4Å; I424-A428 PolarHBondContact O-N 3.27Å
425	A	98.3	Very high	97.6	Very high	0 Å²	0	38.3 Å²	38.3	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-57.9	-43.9	173	0	0	0	0	0	111.1	F269 V332 C421 I422 M427 A428 V429	F269-A425 HydrophobicContact CB-CB 4.02Å; V332-A425 HydrophobicContact CG1-CB 4.28Å; C421-A425 PolarHBondContact O-N 3.02Å; C421-A425 VanDerWaalsContact O-N 3.08Å; I422-A425 WeakPolarHBondContact O-CB 3.43Å; I422-A425 PolarHBondContact O-N 2.96Å; A425-M427 PolarHBondContact O-N 3.12Å; A425-A428 WeakPolarHBondContact O-CB 2.98Å; A425-A428 PolarHBondContact O-N 3.01Å; A425-A428 VanDerWaalsContact O-N 3.14Å; A425-V429 WeakPolarHBondContact O-CG2 3.46Å; A425-V429 PolarHBondContact O-N 2.94Å
426	L	98.4	Very high	97.3	Very high	38 Å²	38	38.9 Å²	38.9	20%	0.199	21%	0.211	C	C	.	.	H	α-helix	trans	-61	-45.8	178.6	-175.1	62.3	0	0	0	112.3	F329 V332 I333 I422 C423 I424 A428 V429 V430	F329-L426 HydrophobicContact CD2-CD1 3.73Å; F329-L426 HydrophobicContact CE2-CD1 3.49Å; F329-L426 VanDerWaalsContact CE2-CD1 3.49Å; F329-L426 HydrophobicContact CZ-CD1 4.31Å; V332-L426 HydrophobicContact CG1-CB 3.76Å; V332-L426 HydrophobicContact CG1-CD1 4.04Å; V332-L426 HydrophobicContact CG1-CG 4.49Å; I333-L426 HydrophobicContact CG1-CD1 3.99Å; I422-L426 WeakPolarHBondContact O-CB 3.35Å; I422-L426 PolarHBondContact O-N 3.24Å; C423-L426 WeakPolarHBondContact O-CB 3.3Å; C423-L426 PolarHBondContact O-N 3.14Å; I424-L426 VanDerWaalsContact C-N 3.3Å; I424-L426 PolarHBondContact O-N 3.01Å; L426-A428 VanDerWaalsContact C-N 3.27Å; L426-A428 PolarHBondContact O-N 3.28Å; L426-V429 PolarHBondContact O-N 3.43Å; L426-V430 WeakPolarHBondContact O-CG2 3.43Å; L426-V430 PolarHBondContact O-N 2.95Å
427	M	98.4	Very high	96.9	Very high	126 Å²	126	44.1 Å²	44.1	62%	0.621	23%	0.226	S	C	*	.	H	α-helix	trans	-59.6	-40.2	174.6	-71.6	-175	-67	0	0	111.5	C423 I424 A425 V430 G431	C423-M427 WeakPolarHBondContact O-CG 3.33Å; C423-M427 PolarHBondContact O-N 2.69Å; I424-M427 HydrophobicContact CB-CE 4.35Å; I424-M427 HydrophobicContact CG1-CE 4Å; I424-M427 PolarHBondContact O-N 3.4Å; A425-M427 PolarHBondContact O-N 3.12Å; M427-V430 PolarHBondContact O-N 3.01Å; M427-G431 PolarHBondContact O-N 3.36Å
428	A	98.3	Very high	96.5	Very high	8 Å²	8	48.2 Å²	48.2	7%	0.066	25%	0.249	C	C	.	.	H	α-helix	trans	-67.9	-38.1	177	0	0	0	0	0	112.8	L262 I265 I266 I424 A425 L426 G431 L432	L262-A428 HydrophobicContact CD2-CB 4.24Å; I265-A428 HydrophobicContact CB-CB 4.16Å; I265-A428 HydrophobicContact CG2-CB 3.64Å; I266-A428 HydrophobicContact CD1-CB 4.39Å; I266-A428 HydrophobicContact CG1-CB 3.61Å; I424-A428 PolarHBondContact O-N 3.27Å; A425-A428 WeakPolarHBondContact O-CB 2.98Å; A425-A428 PolarHBondContact O-N 3.01Å; A425-A428 VanDerWaalsContact O-N 3.14Å; L426-A428 VanDerWaalsContact C-N 3.27Å; L426-A428 PolarHBondContact O-N 3.28Å; A428-G431 PolarHBondContact O-N 2.99Å; A428-L432 WeakPolarHBondContact O-CB 3.32Å; A428-L432 PolarHBondContact O-N 3.19Å
429	V	97.8	Very high	95.9	Very high	1 Å²	1	54 Å²	54	1%	0.006	27%	0.274	C	S	.	.	H	α-helix	trans	-63.6	-43.1	173.3	-179.7	0	0	0	0	111.3	I266 I325 V328 F329 V332 A425 L426 G431 L432 Y433	I266-V429 HydrophobicContact CD1-CB 4.28Å; I266-V429 HydrophobicContact CD1-CG2 3.65Å; I266-V429 HydrophobicContact CG1-CG2 3.73Å; I266-V429 HydrophobicContact CG2-CG2 3.98Å; I325-V429 HydrophobicContact CG2-CG1 3.99Å; V328-V429 HydrophobicContact CG1-CG1 4.27Å; V328-V429 HydrophobicContact CG1-CG2 3.54Å; F329-V429 HydrophobicContact CB-CG1 3.73Å; F329-V429 HydrophobicContact CD2-CG1 3.97Å; F329-V429 HydrophobicContact CG-CG1 4.37Å; V332-V429 HydrophobicContact CG2-CG2 3.98Å; A425-V429 WeakPolarHBondContact O-CG2 3.46Å; A425-V429 PolarHBondContact O-N 2.94Å; L426-V429 PolarHBondContact O-N 3.43Å; V429-G431 VanDerWaalsContact C-N 3.34Å; V429-L432 PolarHBondContact O-N 3.25Å; V429-Y433 PolarHBondContact O-N 2.92Å
430	V	97.6	Very high	95	Very high	56 Å²	56	56.3 Å²	56.3	34%	0.339	30%	0.301	S	S	.	.	H	α-helix	trans	-63.2	-43.5	175.9	171.9	0	0	0	0	110.4	F329 L426 M427 L432 Y433 F434	F329-V430 HydrophobicContact CD2-CG2 4.31Å; F329-V430 HydrophobicContact CE2-CG2 3.78Å; L426-V430 WeakPolarHBondContact O-CG2 3.43Å; L426-V430 PolarHBondContact O-N 2.95Å; M427-V430 PolarHBondContact O-N 3.01Å; V430-L432 VanDerWaalsContact C-N 3.34Å; V430-L432 PolarHBondContact O-N 3.3Å; V430-Y433 WeakPolarHBondContact O-CB 3.48Å; V430-Y433 PolarHBondContact O-N 3.07Å; V430-F434 HydrophobicContact CG1-CD2 3.9Å; V430-F434 HydrophobicContact CG1-CE2 3.55Å; V430-F434 WeakPolarHBondContact O-CD2 3.44Å; V430-F434 PolarHBondContact O-N 3.25Å; V430-F434 VanDerWaalsContact O-N 3.15Å
431	G	97.1	Very high	93.9	Very high	23 Å²	23	56.7 Å²	56.7	24%	0.237	29%	0.294	C	S	.	.	H	α-helix	trans	-57.9	-45.5	172.7	0	0	0	0	0	112.3	M427 A428 V429 Y433 F434 V435	M427-G431 PolarHBondContact O-N 3.36Å; A428-G431 PolarHBondContact O-N 2.99Å; V429-G431 VanDerWaalsContact C-N 3.34Å; G431-Y433 VanDerWaalsContact C-N 3.31Å; G431-Y433 PolarHBondContact O-N 3.3Å; G431-F434 PolarHBondContact O-N 2.88Å; G431-V435 WeakPolarHBondContact O-CG2 3.35Å; G431-V435 PolarHBondContact O-N 3.08Å
432	L	96.6	Very high	93.1	Very high	0 Å²	0	57 Å²	57	0%	0	30%	0.299	C	S	.	.	H	α-helix	trans	-61.9	-40.7	179.3	-177.7	63.9	0	0	0	111.2	L262 I263 I266 I325 M370 A428 V429 V430 F434 V435 D436 L443	L262-L432 HydrophobicContact CB-CB 4.2Å; L262-L432 HydrophobicContact CB-CD1 4.24Å; L262-L432 HydrophobicContact CD1-CB 4.28Å; I263-L432 HydrophobicContact CG1-CD1 4.3Å; I263-L432 HydrophobicContact CG1-CD2 3.82Å; I266-L432 HydrophobicContact CD1-CB 4.4Å; I266-L432 HydrophobicContact CD1-CD2 3.85Å; I325-L432 HydrophobicContact CD1-CD2 4.4Å; I325-L432 HydrophobicContact CD1-CG 3.97Å; I325-L432 HydrophobicContact CG1-CD2 4.24Å; I325-L432 HydrophobicContact CG1-CG 4.35Å; M370-L432 HydrophobicContact CE-CD2 4.35Å; M370-L432 HydrophobicContact SD-CD2 4.43Å; A428-L432 WeakPolarHBondContact O-CB 3.32Å; A428-L432 PolarHBondContact O-N 3.19Å; V429-L432 PolarHBondContact O-N 3.25Å; V430-L432 VanDerWaalsContact C-N 3.34Å; V430-L432 PolarHBondContact O-N 3.3Å; L432-F434 PolarHBondContact O-N 2.99Å; L432-V435 PolarHBondContact O-N 3Å; L432-D436 WeakPolarHBondContact O-CB 3.47Å; L432-D436 PolarHBondContact O-N 3.09Å; L432-L443 HydrophobicContact CD1-CD1 3.81Å; L432-L443 HydrophobicContact CD2-CD1 4.5Å; L432-L443 HydrophobicContact CG-CD1 4.23Å
433	Y	95.6	Very high	92.4	Very high	120 Å²	120	57 Å²	57	47%	0.471	30%	0.299	S	S	.	.	H	α-helix	trans	-58.1	-47.3	174.6	179.6	-98	0	0	0	112.1	I325 V429 V430 G431 Y437	I325-Y433 HydrophobicContact CG2-CD2 4.27Å; V429-Y433 PolarHBondContact O-N 2.92Å; V430-Y433 WeakPolarHBondContact O-CB 3.48Å; V430-Y433 PolarHBondContact O-N 3.07Å; G431-Y433 VanDerWaalsContact C-N 3.31Å; G431-Y433 PolarHBondContact O-N 3.3Å; Y433-Y437 VanDerWaalsContact O-CB 3.31Å; Y433-Y437 WeakPolarHBondContact O-CB 3.26Å; Y433-Y437 PolarHBondContact O-N 3.31Å
434	F	95.1	Very high	92	Very high	115 Å²	115	56.6 Å²	56.6	50%	0.504	29%	0.293	S	S	.	.	H	α-helix	trans	-66.8	-39	178.1	-74.9	-65.5	0	0	0	112.5	V430 G431 L432 Y437 L438	V430-F434 HydrophobicContact CG1-CD2 3.9Å; V430-F434 HydrophobicContact CG1-CE2 3.55Å; V430-F434 WeakPolarHBondContact O-CD2 3.44Å; V430-F434 PolarHBondContact O-N 3.25Å; V430-F434 VanDerWaalsContact O-N 3.15Å; G431-F434 PolarHBondContact O-N 2.88Å; L432-F434 PolarHBondContact O-N 2.99Å; F434-Y437 PolarHBondContact O-N 3.28Å; F434-L438 WeakPolarHBondContact O-CB 3.32Å; F434-L438 VanDerWaalsContact O-CG 3.24Å; F434-L438 WeakPolarHBondContact O-CG 3.5Å; F434-L438 PolarHBondContact O-N 3.02Å
435	V	93.9	Very high	91.3	Very high	19 Å²	19	56.7 Å²	56.7	12%	0.115	29%	0.292	C	S	.	.	H	α-helix	trans	-65.2	-45.7	177.7	176.3	0	0	0	0	110.9	L258 S259 L262 G431 L432 Y437 L438 K439	L258-V435 HydrophobicContact CD2-CG2 3.77Å; L258-V435 HydrophobicContact CG-CG2 4.31Å; S259-V435 WeakPolarHBondContact OG-CG1 3.39Å; L262-V435 HydrophobicContact CD1-CG2 3.95Å; G431-V435 WeakPolarHBondContact O-CG2 3.35Å; G431-V435 PolarHBondContact O-N 3.08Å; L432-V435 PolarHBondContact O-N 3Å; V435-Y437 VanDerWaalsContact C-N 3.35Å; V435-Y437 PolarHBondContact O-N 3.13Å; V435-L438 PolarHBondContact O-N 2.83Å; V435-K439 HydrophobicContact CG1-CD 3.83Å; V435-K439 HydrophobicContact CG1-CG 4.37Å; V435-K439 WeakPolarHBondContact O-CB 3.38Å; V435-K439 PolarHBondContact O-N 3.34Å
436	D	91.5	Very high	90.6	Very high	12 Å²	12	57.3 Å²	57.3	6%	0.064	30%	0.296	C	S	.	.	H	α-helix	trans	-61	-43.3	175.6	-177.1	60	0	0	0	111.4	I325 L432 L438 G440 G442 L443 N444	I325-D436 HydrophobicContact CD1-CB 3.52Å; L432-D436 WeakPolarHBondContact O-CB 3.47Å; L432-D436 PolarHBondContact O-N 3.09Å; D436-L438 PolarHBondContact O-N 3.44Å; D436-G440 WeakPolarHBondContact O-CA 3.38Å; D436-G440 PolarHBondContact O-N 3.35Å; D436-G442 PolarHBondContact OD1-N 3.35Å; D436-G442 VanDerWaalsContact OD1-N 3.14Å; D436-L443 HydrophobicContact CB-CD1 4.28Å; D436-L443 WeakPolarHBondContact OD1-CB 3.32Å; D436-L443 PolarHBondContact OD1-N 3Å; D436-N444 PolarHBondContact OD2-ND2 2.97Å
437	Y	89.2	Confident	89.7	Confident	173 Å²	173	57.7 Å²	57.7	68%	0.678	31%	0.305	S	S	*	.	H	α-helix	trans	-62.6	-41.4	178	-178.8	-101.4	0	0	0	112.8	Y433 F434 V435	Y433-Y437 VanDerWaalsContact O-CB 3.31Å; Y433-Y437 WeakPolarHBondContact O-CB 3.26Å; Y433-Y437 PolarHBondContact O-N 3.31Å; F434-Y437 PolarHBondContact O-N 3.28Å; V435-Y437 VanDerWaalsContact C-N 3.35Å; V435-Y437 PolarHBondContact O-N 3.13Å
438	L	89.4	Confident	88.7	Confident	141 Å²	141	55.3 Å²	55.3	74%	0.738	31%	0.306	S	S	*	.	H	α-helix	trans	-78.9	-34.9	-177.9	-69.4	172.7	0	0	0	113.2	F434 V435 D436	F434-L438 WeakPolarHBondContact O-CB 3.32Å; F434-L438 VanDerWaalsContact O-CG 3.24Å; F434-L438 WeakPolarHBondContact O-CG 3.5Å; F434-L438 PolarHBondContact O-N 3.02Å; V435-L438 PolarHBondContact O-N 2.83Å; D436-L438 PolarHBondContact O-N 3.44Å
439	K	86.8	Confident	87.9	Confident	121 Å²	121	59.8 Å²	59.8	53%	0.526	33%	0.325	S	S	.	.	H	α-helix	trans	-95.4	-17.2	-176.7	-66.6	-173.4	178.8	-178.4	0	114.1	V435 E441	V435-K439 HydrophobicContact CG1-CD 3.83Å; V435-K439 HydrophobicContact CG1-CG 4.37Å; V435-K439 WeakPolarHBondContact O-CB 3.38Å; V435-K439 PolarHBondContact O-N 3.34Å; K439-E441 HydrophobicContact CB-CG 3.99Å; K439-E441 WeakPolarHBondContact CD-OE1 3.45Å
440	G	78.6	Confident	87.2	Confident	62 Å²	62	61.4 Å²	61.4	64%	0.639	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	66.7	34.3	-178.8	0	0	0	0	0	113.7	D436 G442	D436-G440 WeakPolarHBondContact O-CA 3.38Å; D436-G440 PolarHBondContact O-N 3.35Å; G440-G442 PolarHBondContact O-N 3.49Å; G440-G442 VanDerWaalsContact O-N 3.1Å
441	E	76.3	Confident	86.3	Confident	56 Å²	56	60.9 Å²	60.9	26%	0.262	33%	0.333	S	S	.	.			trans	-67	-8.8	-177.6	-69.9	-178.6	-177.3	0	0	113.4	S259 K439 L443	S259-E441 WeakPolarHBondContact CB-OE2 3.37Å; S259-E441 PolarHBondContact OG-OE1 2.9Å; S259-E441 PolarHBondContact OG-OE2 3Å; K439-E441 HydrophobicContact CB-CG 3.99Å; K439-E441 WeakPolarHBondContact CD-OE1 3.45Å; E441-L443 VanDerWaalsContact C-N 3.28Å; E441-L443 PolarHBondContact O-N 2.94Å
442	G	81.3	Confident	85.7	Confident	14 Å²	14	65.9 Å²	65.9	14%	0.144	35%	0.348	C	S	.	.			trans	72.6	21.3	171.1	0	0	0	0	0	113.2	D436 G440 N444 Q445 R450	D436-G442 PolarHBondContact OD1-N 3.35Å; D436-G442 VanDerWaalsContact OD1-N 3.14Å; G440-G442 PolarHBondContact O-N 3.49Å; G440-G442 VanDerWaalsContact O-N 3.1Å; G442-N444 PolarHBondContact O-N 2.69Å; G442-N444 VanDerWaalsContact O-N 3.13Å; G442-Q445 VanDerWaalsContact O-CB 3.32Å; G442-Q445 WeakPolarHBondContact O-CB 3.09Å; G442-Q445 WeakPolarHBondContact O-CG 3.47Å; G442-Q445 PolarHBondContact O-N 3.14Å; G442-R450 PolarHBondContact O-NH1 2.91Å
443	L	84.3	Confident	84.9	Confident	0 Å²	0	69.4 Å²	69.4	0%	0	37%	0.366	C	S	.	.	T	Hydrogen-bonded Turn	trans	-59	-29.6	179.6	-75.2	175.8	0	0	0	112.1	N324 I325 M370 F373 V374 L432 D436 E441	N324-L443 PolarHBondContact ND2-O 3.22Å; I325-L443 HydrophobicContact CD1-CB 3.89Å; I325-L443 HydrophobicContact CD1-CD1 3.96Å; I325-L443 HydrophobicContact CG1-CB 4.06Å; I325-L443 HydrophobicContact CG1-CD1 4.44Å; M370-L443 HydrophobicContact CB-CD2 3.96Å; M370-L443 HydrophobicContact CG-CD2 3.99Å; M370-L443 HydrophobicContact SD-CB 4.45Å; M370-L443 HydrophobicContact SD-CD1 4.49Å; M370-L443 HydrophobicContact SD-CD2 4.17Å; F373-L443 HydrophobicContact CB-CD2 3.95Å; F373-L443 HydrophobicContact CD2-CD2 4.37Å; V374-L443 HydrophobicContact CG2-CD1 4.2Å; V374-L443 HydrophobicContact CG2-CD2 3.4Å; V374-L443 HydrophobicContact CG2-CG 4.1Å; L432-L443 HydrophobicContact CD1-CD1 3.81Å; L432-L443 HydrophobicContact CD2-CD1 4.5Å; L432-L443 HydrophobicContact CG-CD1 4.23Å; D436-L443 HydrophobicContact CB-CD1 4.28Å; D436-L443 WeakPolarHBondContact OD1-CB 3.32Å; D436-L443 PolarHBondContact OD1-N 3Å; E441-L443 VanDerWaalsContact C-N 3.28Å; E441-L443 PolarHBondContact O-N 2.94Å
444	N	88.6	Confident	84.1	Confident	42 Å²	42	70.2 Å²	70.2	23%	0.225	37%	0.374	C	S	.	.	T	Hydrogen-bonded Turn	trans	-86.1	2.2	178.8	-71.3	-55.6	0	0	0	115.1	R323 N324 I325 D436 G442	R323-N444 VanDerWaalsContact C-OD1 3.24Å; R323-N444 VanDerWaalsContact CA-OD1 3.25Å; R323-N444 WeakPolarHBondContact CA-OD1 3.34Å; R323-N444 PolarHBondContact N-O 3.01Å; N324-N444 PolarHBondContact N-OD1 2.94Å; I325-N444 WeakPolarHBondContact CB-OD1 3.33Å; I325-N444 PolarHBondContact N-OD1 3.27Å; D436-N444 PolarHBondContact OD2-ND2 2.97Å; G442-N444 PolarHBondContact O-N 2.69Å; G442-N444 VanDerWaalsContact O-N 3.13Å
445	Q	85.1	Confident	83.3	Confident	63 Å²	63	71.5 Å²	71.5	29%	0.294	38%	0.38	S	S	.	.			trans	-68	152.6	175.1	-66.7	174.3	-8.6	0	0	111.4	G322 G442 E449 R450	G322-Q445 WeakPolarHBondContact CA-O 3.39Å; G442-Q445 VanDerWaalsContact O-CB 3.32Å; G442-Q445 WeakPolarHBondContact O-CB 3.09Å; G442-Q445 WeakPolarHBondContact O-CG 3.47Å; G442-Q445 PolarHBondContact O-N 3.14Å; Q445-E449 WeakPolarHBondContact CA-OE2 3.43Å; Q445-E449 HydrophobicContact CB-CB 4.3Å; Q445-R450 HydrophobicContact CB-CG 4.06Å; Q445-R450 PolarHBondContact O-NH1 2.89Å; Q445-R450 PolarHBondContact O-NH2 2.88Å
446	S	83.3	Confident	82.6	Confident	13 Å²	13	74 Å²	74	9%	0.091	39%	0.39	C	S	.	.			trans	-81.2	165.1	170.7	64.3	0	0	0	0	111.7	A448 E449 R450	S446-A448 PolarHBondContact O-N 3.49Å; S446-E449 PolarHBondContact N-OE2 3.45Å; S446-E449 PolarHBondContact O-N 3.48Å; S446-E449 WeakPolarHBondContact OG-CB 3.5Å; S446-E449 VanDerWaalsContact OG-CD 3.25Å; S446-E449 VanDerWaalsContact OG-CG 3.25Å; S446-E449 WeakPolarHBondContact OG-CG 3.36Å; S446-E449 PolarHBondContact OG-N 3.12Å; S446-E449 PolarHBondContact OG-OE2 2.54Å; S446-R450 PolarHBondContact O-N 3.39Å
447	A	79	Confident	82	Confident	47 Å²	47	77.8 Å²	77.8	39%	0.388	41%	0.414	S	S	.	.	H	α-helix	trans	-60.4	-35.8	175.3	0	0	0	0	0	112.6	D319 A451	D319-A447 WeakPolarHBondContact O-CB 3.49Å; D319-A447 PolarHBondContact O-N 3.47Å; D319-A447 VanDerWaalsContact O-N 3.07Å; A447-A451 WeakPolarHBondContact O-CB 3.42Å; A447-A451 PolarHBondContact O-N 3.44Å
448	A	78.3	Confident	81.3	Confident	76 Å²	76	72.2 Å²	72.2	63%	0.628	40%	0.404	S	S	*	.	H	α-helix	trans	-68.5	-41.6	178.4	0	0	0	0	0	112.2	S446 A451 K452	S446-A448 PolarHBondContact O-N 3.49Å; A448-A451 PolarHBondContact O-N 3.12Å; A448-K452 PolarHBondContact O-N 3.39Å
449	E	81.8	Confident	80.5	Confident	102 Å²	102	72 Å²	72	48%	0.477	40%	0.399	S	S	.	.	H	α-helix	trans	-64.7	-45	176.2	-72.6	163.2	157	0	0	111.4	Q445 S446 A451 K452 L453	Q445-E449 WeakPolarHBondContact CA-OE2 3.43Å; Q445-E449 HydrophobicContact CB-CB 4.3Å; S446-E449 PolarHBondContact N-OE2 3.45Å; S446-E449 PolarHBondContact O-N 3.48Å; S446-E449 WeakPolarHBondContact OG-CB 3.5Å; S446-E449 VanDerWaalsContact OG-CD 3.25Å; S446-E449 VanDerWaalsContact OG-CG 3.25Å; S446-E449 WeakPolarHBondContact OG-CG 3.36Å; S446-E449 PolarHBondContact OG-N 3.12Å; S446-E449 PolarHBondContact OG-OE2 2.54Å; E449-A451 PolarHBondContact O-N 3.25Å; E449-K452 WeakPolarHBondContact O-CB 3.2Å; E449-K452 PolarHBondContact O-N 3.25Å; E449-L453 PolarHBondContact O-N 2.94Å
450	R	81.9	Confident	79.6	Confident	34 Å²	34	74.2 Å²	74.2	13%	0.128	41%	0.411	C	S	.	.	H	α-helix	trans	-59.6	-45.3	175.3	-78.8	-168.9	-87.4	-83.1	-8.5	112.3	G442 Q445 S446 K452 L453 Q454	G442-R450 PolarHBondContact O-NH1 2.91Å; Q445-R450 HydrophobicContact CB-CG 4.06Å; Q445-R450 PolarHBondContact O-NH1 2.89Å; Q445-R450 PolarHBondContact O-NH2 2.88Å; S446-R450 PolarHBondContact O-N 3.39Å; R450-K452 VanDerWaalsContact C-N 3.26Å; R450-K452 PolarHBondContact O-N 3.13Å; R450-L453 PolarHBondContact O-N 2.96Å; R450-Q454 WeakPolarHBondContact O-CG 3.46Å; R450-Q454 PolarHBondContact O-N 2.8Å
451	A	79.9	Confident	78.9	Confident	45 Å²	45	75.5 Å²	75.5	37%	0.372	42%	0.415	S	S	.	.	H	α-helix	trans	-63.2	-33	177.7	0	0	0	0	0	112.5	A447 A448 E449 K455	A447-A451 WeakPolarHBondContact O-CB 3.42Å; A447-A451 PolarHBondContact O-N 3.44Å; A448-A451 PolarHBondContact O-N 3.12Å; E449-A451 PolarHBondContact O-N 3.25Å; A451-K455 WeakPolarHBondContact O-CG 3.49Å; A451-K455 PolarHBondContact O-N 2.81Å
452	K	83	Confident	77.5	Confident	128 Å²	128	83.4 Å²	83.4	56%	0.557	45%	0.452	S	S	*	.	H	α-helix	trans	-69.2	-47.8	175.5	-165.9	-172.5	-178	-119.9	0	111.4	A448 E449 R450 Q454 K455 E456	A448-K452 PolarHBondContact O-N 3.39Å; E449-K452 WeakPolarHBondContact O-CB 3.2Å; E449-K452 PolarHBondContact O-N 3.25Å; R450-K452 VanDerWaalsContact C-N 3.26Å; R450-K452 PolarHBondContact O-N 3.13Å; K452-Q454 VanDerWaalsContact C-N 3.33Å; K452-Q454 PolarHBondContact O-N 2.68Å; K452-K455 PolarHBondContact O-N 3.24Å; K452-E456 WeakPolarHBondContact CE-OE1 3.32Å; K452-E456 IonicContact NZ-OE1 3.18Å; K452-E456 PolarHBondContact NZ-OE1 3.25Å; K452-E456 WeakPolarHBondContact O-CG 3.29Å; K452-E456 PolarHBondContact O-N 3.05Å
453	L	80.7	Confident	77.3	Confident	74 Å²	74	86.9 Å²	86.9	39%	0.387	47%	0.468	S	S	.	.	H	α-helix	trans	-59.3	-41.7	176.8	-86.2	150.3	0	0	0	112.5	E449 R450 E456 T457	E449-L453 PolarHBondContact O-N 2.94Å; R450-L453 PolarHBondContact O-N 2.96Å; L453-E456 PolarHBondContact O-N 3.32Å; L453-T457 WeakPolarHBondContact O-CB 3.37Å; L453-T457 PolarHBondContact O-N 2.93Å; L453-T457 PolarHBondContact O-OG1 3.34Å
454	Q	79.3	Confident	76.9	Confident	138 Å²	138	91.5 Å²	91.5	65%	0.645	49%	0.492	S	S	*	.	H	α-helix	trans	-63	-40.9	176.3	-76.1	178.5	-21	0	0	112.1	R450 K452 T457 A458	R450-Q454 WeakPolarHBondContact O-CG 3.46Å; R450-Q454 PolarHBondContact O-N 2.8Å; K452-Q454 VanDerWaalsContact C-N 3.33Å; K452-Q454 PolarHBondContact O-N 2.68Å; Q454-T457 PolarHBondContact O-N 3.31Å; Q454-A458 WeakPolarHBondContact O-CB 3.39Å; Q454-A458 PolarHBondContact O-N 2.83Å
455	K	77.1	Confident	76.3	Confident	141 Å²	141	94.2 Å²	94.2	61%	0.613	51%	0.507	S	S	*	.	H	α-helix	trans	-65.5	-48.3	175.1	-75.3	179.5	176.5	-169.7	0	112.1	A451 K452 T457 A458 E459	A451-K455 WeakPolarHBondContact O-CG 3.49Å; A451-K455 PolarHBondContact O-N 2.81Å; K452-K455 PolarHBondContact O-N 3.24Å; K455-T457 PolarHBondContact O-N 3.13Å; K455-A458 PolarHBondContact O-N 3.17Å; K455-A458 VanDerWaalsContact O-N 3.16Å; K455-E459 WeakPolarHBondContact O-CB 3.33Å; K455-E459 WeakPolarHBondContact O-CG 3.37Å; K455-E459 PolarHBondContact O-N 3.28Å
456	E	80.4	Confident	75.8	Confident	72 Å²	72	96.1 Å²	96.1	34%	0.336	52%	0.52	S	S	.	.	H	α-helix	trans	-59.3	-38.4	177.6	-71.2	171.6	177.7	0	0	111.1	K452 L453 H460	K452-E456 WeakPolarHBondContact CE-OE1 3.32Å; K452-E456 IonicContact NZ-OE1 3.18Å; K452-E456 PolarHBondContact NZ-OE1 3.25Å; K452-E456 WeakPolarHBondContact O-CG 3.29Å; K452-E456 PolarHBondContact O-N 3.05Å; L453-E456 PolarHBondContact O-N 3.32Å; E456-H460 WeakPolarHBondContact O-CB 3.43Å; E456-H460 PolarHBondContact O-CD2 3.23Å; E456-H460 PolarHBondContact O-N 2.87Å
457	T	77.7	Confident	75.3	Confident	92 Å²	92	101.3 Å²	101.3	56%	0.564	55%	0.547	S	S	*	.	H	α-helix	trans	-69.3	-39.3	176.9	-52.3	0	0	0	0	112.2	L453 Q454 K455 H460 A461	L453-T457 WeakPolarHBondContact O-CB 3.37Å; L453-T457 PolarHBondContact O-N 2.93Å; L453-T457 PolarHBondContact O-OG1 3.34Å; Q454-T457 PolarHBondContact O-N 3.31Å; K455-T457 PolarHBondContact O-N 3.13Å; T457-H460 PolarHBondContact O-N 3.04Å; T457-A461 WeakPolarHBondContact O-CB 3.42Å; T457-A461 PolarHBondContact O-N 2.69Å
458	A	74.1	Confident	75.1	Confident	56 Å²	56	104.9 Å²	104.9	46%	0.463	56%	0.557	S	S	.	*	H	α-helix	trans	-67.7	-43.3	177.1	0	0	0	0	0	111.8	Q454 K455 H460 A461 E462	Q454-A458 WeakPolarHBondContact O-CB 3.39Å; Q454-A458 PolarHBondContact O-N 2.83Å; K455-A458 PolarHBondContact O-N 3.17Å; K455-A458 VanDerWaalsContact O-N 3.16Å; A458-H460 PolarHBondContact O-N 3.49Å; A458-A461 PolarHBondContact O-N 3.4Å; A458-A461 VanDerWaalsContact O-N 3.1Å; A458-E462 PolarHBondContact O-N 3.03Å
459	E	73.4	Confident	74.8	Confident	135 Å²	135	106.9 Å²	106.9	63%	0.631	55%	0.552	S	S	*	*	H	α-helix	trans	-65.2	-23.5	176.9	-72.1	173.4	-173.8	0	0	113.1	K455	K455-E459 WeakPolarHBondContact O-CB 3.33Å; K455-E459 WeakPolarHBondContact O-CG 3.37Å; K455-E459 PolarHBondContact O-N 3.28Å
460	H	68.5	Low	74.3	Confident	168 Å²	168	107.3 Å²	107.3	78%	0.778	56%	0.558	S	S	*	*	H	α-helix	trans	-89.2	-13.7	174	-82.4	-56.1	0	0	0	114.2	E456 T457 A458	E456-H460 WeakPolarHBondContact O-CB 3.43Å; E456-H460 PolarHBondContact O-CD2 3.23Å; E456-H460 PolarHBondContact O-N 2.87Å; T457-H460 PolarHBondContact O-N 3.04Å; A458-H460 PolarHBondContact O-N 3.49Å
461	A	63	Low	73.7	Confident	89 Å²	89	113.4 Å²	113.4	74%	0.736	59%	0.594	S	S	*	*	H	α-helix	trans	-93.1	-19.7	178.2	0	0	0	0	0	112.9	T457 A458	T457-A461 WeakPolarHBondContact O-CB 3.42Å; T457-A461 PolarHBondContact O-N 2.69Å; A458-A461 PolarHBondContact O-N 3.4Å; A458-A461 VanDerWaalsContact O-N 3.1Å
462	E	47.1	Very low	73.1	Confident	223 Å²	223	119.6 Å²	119.6	100%	1.042	61%	0.614	S	S	*	*			trans	-79.5	0	163	-68.3	-177.3	167.4	0	0	111.2	A458	A458-E462 PolarHBondContact O-N 3.03Å

Retrieved 462 of 462 residues in 248 ms (Link to these results)

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