A0A087XXK1_POEFO Loading...

Trehalase

AlphaFold DB , UniProt , Accession A0A087XXK1, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 579 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M42.7Very low32.8Very low241 Ų241163.1 Ų163.1100%1.18784%0.835SS**  097.70-89.5169.669.500107.3
2E32Very low33Very low198 Ų198161.4 Ų161.493%0.92583%0.826SS**  trans-138107.1164.3-77.7-169.4160.200107.5
3S31.6Very low33.2Very low121 Ų121157.9 Ų157.985%0.84682%0.817SS**  trans-74.5122.4-179.4-63.80000109.8
4R32.3Very low33.2Very low241 Ų241156.7 Ų156.791%0.90981%0.812SS**  trans-89.4113.7166.5-73.7-173.8175.1-172.1-1.5109
5V34.1Very low33.4Very low115 Ų115159.3 Ų159.370%0.69782%0.815SS**  trans-77.2120.7170.6176.50000108F7V5-F7 HydrophobicContact CG1-CD2 3.98Å; V5-F7 HydrophobicContact CG1-CE2 3.88Å
6V32.4Very low33.6Very low124 Ų124157.6 Ų157.675%0.75281%0.806SS**  trans-94.4114.1172.3176.90000107.7
7F30.8Very low33.8Very low167 Ų167155.2 Ų155.273%0.73281%0.806SS**  trans-84.4110.2169-89.1-89.2000109.2V5 F9V5-F7 HydrophobicContact CG1-CD2 3.98Å; V5-F7 HydrophobicContact CG1-CE2 3.88Å; F7-F9 HydrophobicContact CB-CE2 4.3Å; F7-F9 PolarHBondContact O-N 2.97Å
8C29.7Very low34Very low118 Ų118152.8 Ų152.880%0.79780%0.799SS**  trans-80.4107165.9-82.20000109.2S10C8-S10 PolarHBondContact O-N 3.1Å
9F31.6Very low34.7Very low172 Ų172153.5 Ų153.575%0.75479%0.794SS**  trans-80.4108.7164.6-81-87.7000108.8F7 F11F7-F9 HydrophobicContact CB-CE2 4.3Å; F7-F9 PolarHBondContact O-N 2.97Å; F9-F11 PolarHBondContact O-N 2.97Å
10S31.9Very low35.6Very low107 Ų107151.7 Ų151.775%0.74879%0.794SS**  trans-74.4108.2164.3-76.80000108.5C8 I12C8-S10 PolarHBondContact O-N 3.1Å; S10-I12 PolarHBondContact O-N 2.85Å
11F32.1Very low37.6Very low190 Ų190149.4 Ų149.483%0.83379%0.791SS**  trans-75.3101.4164.2-84.6-89.7000108.1F9 T13F9-F11 PolarHBondContact O-N 2.97Å; F11-T13 PolarHBondContact O-N 3.21Å
12I35.3Very low39.7Very low143 Ų143140.5 Ų140.573%0.73375%0.748SS**  trans-78.398.3162.3-63.3174.7000105.8S10 L14S10-I12 PolarHBondContact O-N 2.85Å; I12-L14 HydrophobicContact CG2-CD1 4.44Å; I12-L14 PolarHBondContact O-N 2.63Å
13T35.5Very low42.6Very low116 Ų116133.1 Ų133.171%0.71272%0.717SS**  trans-70.198.4166.9-0.10000107.7F11 F15F11-T13 PolarHBondContact O-N 3.21Å; T13-F15 PolarHBondContact O-N 2.86Å
14L33.2Very low45.5Very low141 Ų141128.8 Ų128.874%0.73869%0.686SS**  trans-67.1100.8167.7-140.787.8000107I12 I16I12-L14 HydrophobicContact CG2-CD1 4.44Å; I12-L14 PolarHBondContact O-N 2.63Å; L14-I16 VanDerWaalsContact C-N 3.31Å; L14-I16 PolarHBondContact O-N 3.1Å
15F35.6Very low48.5Very low195 Ų195117.3 Ų117.386%0.85564%0.643SS**  trans-66.597.1165.5-92.7-89.3000107.1T13 C17T13-F15 PolarHBondContact O-N 2.86Å; F15-C17 VanDerWaalsContact C-N 3.31Å; F15-C17 PolarHBondContact O-N 2.8Å
16I37.1Very low51.4Low132 Ų132112 Ų11268%0.67761%0.611SS**  trans-64.9102.2162-61.7173.2000104.9L14 V18L14-I16 VanDerWaalsContact C-N 3.31Å; L14-I16 PolarHBondContact O-N 3.1Å; I16-V18 HydrophobicContact CG2-CG2 4.1Å; I16-V18 PolarHBondContact O-N 3.23Å
17C36.8Very low54.4Low118 Ų118114.3 Ų114.380%0.79761%0.607SS**  trans-67.187.7167.9-162.30000106.4F15 K19F15-C17 VanDerWaalsContact C-N 3.31Å; F15-C17 PolarHBondContact O-N 2.8Å; C17-K19 PolarHBondContact O-N 3.48Å
18V38.1Very low57.6Low112 Ų112107.9 Ų107.968%0.67958%0.583SS**  trans-63.4107163.9-179.90000104.2I16 C20I16-V18 HydrophobicContact CG2-CG2 4.1Å; I16-V18 PolarHBondContact O-N 3.23Å; V18-C20 VanDerWaalsContact C-N 3.27Å; V18-C20 PolarHBondContact O-N 2.83Å
19K45.8Very low60.7Low165 Ų165107.8 Ų107.872%0.71757%0.571SS**  trans-53.8103.5162.5-84.4-172.1174.3-171.70104.9C17 S21 E302C17-K19 PolarHBondContact O-N 3.48Å; K19-S21 PolarHBondContact O-N 3.4Å; K19-E302 IonicContact NZ-OE1 3.92Å
20C52.8Low63.9Low117 Ų11799.7 Ų99.779%0.79154%0.535SS*.  trans-65.2109.5175.8-158.90000105.3V18 L22V18-C20 VanDerWaalsContact C-N 3.27Å; V18-C20 PolarHBondContact O-N 2.83Å; C20-L22 PolarHBondContact O-N 2.96Å
21S77.1Confident67Low104 Ų10494.8 Ų94.873%0.72750%0.501SS*.PPolyproline II helixtrans-63.5131.9177.247.30000108.3K19K19-S21 PolarHBondContact O-N 3.4Å
22L88.4Confident70.1Confident54 Ų5485.9 Ų85.928%0.28346%0.462SS..PPolyproline II helixtrans-63.3150.4174.9-71.6170.6000109.4C20 E280 D282 M309C20-L22 PolarHBondContact O-N 2.96Å; L22-E280 HydrophobicContact CD2-CB 4.1Å; L22-D282 HydrophobicContact CB-CB 4.01Å; L22-D282 HydrophobicContact CD1-CB 3.79Å; L22-M309 HydrophobicContact CD1-CE 4.18Å; L22-M309 HydrophobicContact CD1-CG 4.42Å; L22-M309 HydrophobicContact CD1-SD 3.42Å; L22-M309 WeakPolarHBondContact CD1-SD 3.15Å
23P92.4Very high73Confident43 Ų4380.4 Ų80.428%0.27944%0.436SS..PPolyproline II helixtrans-69.7153.4-179.729.2-34.9000111.2E280 A281P23-E280 WeakPolarHBondContact CD-O 3.43Å; P23-E280 WeakPolarHBondContact CG-O 3.23Å; P23-A281 WeakPolarHBondContact O-CA 3.33Å
24P93.3Very high75.9Confident31 Ų3176.3 Ų76.320%0.20142%0.417CS..PPolyproline II helixtrans-66.7165.6171.330.5-36.7000111.5C26 Y27 R219 L283P24-C26 WeakPolarHBondContact CB-O 3.43Å; P24-C26 WeakPolarHBondContact CG-O 3.41Å; P24-C26 PolarHBondContact O-N 2.9Å; P24-C26 VanDerWaalsContact O-N 3.11Å; P24-Y27 HydrophobicContact CG-CD1 4.39Å; P24-R219 PolarHBondContact O-NE 3.3Å; P24-L283 HydrophobicContact CB-CD1 3.87Å
25P94.4Very high78.9Confident0 Ų072 Ų720%040%0.398CS..SBendtrans-52.6-32175.3-2734.2000113.8C32 R219 L283 P286P25-C32 HydrophobicContact CB-CB 4.31Å; P25-R219 WeakPolarHBondContact O-CG 3.31Å; P25-L283 HydrophobicContact CG-CB 4.31Å; P25-P286 HydrophobicContact CB-CG 4.07Å; P25-P286 HydrophobicContact CG-CG 4.18Å
26C95.4Very high81.8Confident2 Ų262.7 Ų62.71%0.01436%0.357CS..SBendtrans-160173.8164.182.60000109.5P24 S28 C32 V215P24-C26 WeakPolarHBondContact CB-O 3.43Å; P24-C26 WeakPolarHBondContact CG-O 3.41Å; P24-C26 PolarHBondContact O-N 2.9Å; P24-C26 VanDerWaalsContact O-N 3.11Å; C26-S28 VanDerWaalsContact C-N 3.28Å; C26-S28 PolarHBondContact O-N 3.27Å; C26-S28 VanDerWaalsContact SG-CB 3.59Å; C26-S28 PolarHBondContact SG-N 3.05Å; C26-S28 VanDerWaalsContact SG-N 3.43Å; C26-C32 HydrophobicContact CB-CB 3.91Å; C26-C32 WeakPolarHBondContact CB-SG 3.4Å; C26-C32 WeakPolarHBondContact O-CB 3.23Å; C26-C32 WeakPolarHBondContact SG-CB 3.46Å; C26-C32 CovalentContact SG-SG 2.02Å; C26-C32 PolarHBondContact SG-SG 3.24Å; C26-V215 HydrophobicContact CB-CB 4.41Å; C26-V215 WeakPolarHBondContact CB-O 3.37Å
27Y95.1Very high84.7Confident173 Ų17356.5 Ų56.568%0.67833%0.325SS*.SBendtrans-81.41.8-177.3-64.9-66.9000114.9P24 E29 R219P24-Y27 HydrophobicContact CG-CD1 4.39Å; Y27-E29 PolarHBondContact O-N 3.25Å; Y27-R219 PolarHBondContact OH-NH2 2.98Å
28S96.9Very high87.6Confident32 Ų3253.8 Ų53.822%0.22430%0.301CS..  trans-74.5116.7175.8-179.20000111.4C26 I30 Y31 C32 S33C26-S28 VanDerWaalsContact C-N 3.28Å; C26-S28 PolarHBondContact O-N 3.27Å; C26-S28 VanDerWaalsContact SG-CB 3.59Å; C26-S28 PolarHBondContact SG-N 3.05Å; C26-S28 VanDerWaalsContact SG-N 3.43Å; S28-I30 PolarHBondContact O-N 2.96Å; S28-I30 PolarHBondContact OG-N 3.3Å; S28-Y31 WeakPolarHBondContact OG-CD2 3.44Å; S28-Y31 PolarHBondContact OG-N 3.45Å; S28-C32 WeakPolarHBondContact O-CB 3.45Å; S28-C32 PolarHBondContact O-N 2.93Å; S28-S33 PolarHBondContact O-N 3.3Å
29E96.7Very high90.4Very high117 Ų11751 Ų5155%0.54728%0.28SS..THydrogen-bonded Turntrans-72.94.1171.7-63.2-177.5-142.300113.8Y27 S33 L65Y27-E29 PolarHBondContact O-N 3.25Å; E29-S33 CarbonylContact C-O 3.36Å; E29-L65 HydrophobicContact CB-CD2 4.36Å
30I98Very high92.8Very high2 Ų243.3 Ų43.31%0.0125%0.246CC..THydrogen-bonded Turntrans-113.4-46.9176.8-58.3-177.9000110.5S28 I36 L37 F52 L57 P61 V64 L65 F93S28-I30 PolarHBondContact O-N 2.96Å; S28-I30 PolarHBondContact OG-N 3.3Å; I30-I36 HydrophobicContact CD1-CD1 4.46Å; I30-I36 HydrophobicContact CG1-CD1 4.16Å; I30-I36 HydrophobicContact CG2-CG2 4.21Å; I30-L37 WeakPolarHBondContact O-CB 3.1Å; I30-F52 HydrophobicContact CG2-CZ 4.38Å; I30-L57 HydrophobicContact CD1-CD1 3.82Å; I30-L57 HydrophobicContact CD1-CD2 4.21Å; I30-L57 HydrophobicContact CG2-CD2 4.29Å; I30-P61 HydrophobicContact CD1-CB 3.89Å; I30-V64 HydrophobicContact CD1-CB 4.29Å; I30-V64 HydrophobicContact CD1-CG1 4.26Å; I30-L65 HydrophobicContact CD1-CD2 4.49Å; I30-L65 HydrophobicContact CD1-CG 4.16Å; I30-L65 HydrophobicContact CG1-CD2 3.97Å; I30-L65 HydrophobicContact CG1-CG 4.14Å; I30-F93 HydrophobicContact CG2-CE1 4.1Å; I30-F93 HydrophobicContact CG2-CZ 3.91Å
31Y97.7Very high94.9Very high4 Ų437.9 Ų37.92%0.01621%0.21CC..THydrogen-bonded Turntrans-97.6-16.9-173-60.8-59.8000114.3S28 M55 L57 F93 L151 V215 P286S28-Y31 WeakPolarHBondContact OG-CD2 3.44Å; S28-Y31 PolarHBondContact OG-N 3.45Å; Y31-M55 WeakPolarHBondContact CE1-O 3.42Å; Y31-M55 PolarHBondContact OH-O 3.25Å; Y31-L57 WeakPolarHBondContact OH-CG 3.38Å; Y31-L57 PolarHBondContact OH-N 3.37Å; Y31-F93 HydrophobicContact CE1-CE1 4.35Å; Y31-L151 PolarHBondContact OH-O 3.44Å; Y31-V215 HydrophobicContact CD2-CG2 4.5Å; Y31-P286 WeakPolarHBondContact O-CB 3.44Å
32C96.9Very high95.8Very high2 Ų238.2 Ų38.21%0.01420%0.2CC..THydrogen-bonded Turntrans-128.4-18.8-172.7-66.40000114.9P25 C26 S28 Y216 P286P25-C32 HydrophobicContact CB-CB 4.31Å; C26-C32 HydrophobicContact CB-CB 3.91Å; C26-C32 WeakPolarHBondContact CB-SG 3.4Å; C26-C32 WeakPolarHBondContact O-CB 3.23Å; C26-C32 WeakPolarHBondContact SG-CB 3.46Å; C26-C32 CovalentContact SG-SG 2.02Å; C26-C32 PolarHBondContact SG-SG 3.24Å; S28-C32 WeakPolarHBondContact O-CB 3.45Å; S28-C32 PolarHBondContact O-N 2.93Å; C32-Y216 VanDerWaalsContact SG-CA 3.59Å; C32-P286 HydrophobicContact CB-CG 4.35Å
33S95.6Very high96.1Very high28 Ų2836.3 Ų36.320%0.19619%0.192CC..SBendtrans-158.8-173.217964.90000109.2S28 E29S28-S33 PolarHBondContact O-N 3.3Å; E29-S33 CarbonylContact C-O 3.36Å
34G95.7Very high96.3Very high31 Ų3139 Ų3932%0.3220%0.199SC..Hα-helixtrans86.2172.4170.200000114.9I36 H38G34-I36 PolarHBondContact O-N 3.02Å; G34-H38 PolarHBondContact O-N 3.07Å
35P96Very high96.4Very high50 Ų5038.9 Ų38.933%0.32520%0.197SC..Hα-helixtrans-72-28.4-170.128.9-35.9000113.1H39 F68 L72P35-H39 PolarHBondContact O-N 3.26Å; P35-H39 VanDerWaalsContact O-N 3.08Å; P35-H39 PolarHBondContact O-ND1 3.12Å; P35-F68 HydrophobicContact CB-CD1 4.45Å; P35-F68 HydrophobicContact CB-CE1 4.08Å; P35-F68 HydrophobicContact CG-CD1 4.42Å; P35-L72 HydrophobicContact CB-CD1 4.09Å; P35-L72 HydrophobicContact CG-CD1 4.33Å
36I97.9Very high96.4Very high0 Ų041.8 Ų41.80%021%0.209CC..Hα-helixtrans-64-54.7177.2-65.8176.4000109.7I30 G34 H38 H39 M40 F52 V64 L65 F68 F88 F93I30-I36 HydrophobicContact CD1-CD1 4.46Å; I30-I36 HydrophobicContact CG1-CD1 4.16Å; I30-I36 HydrophobicContact CG2-CG2 4.21Å; G34-I36 PolarHBondContact O-N 3.02Å; I36-H38 VanDerWaalsContact C-N 3.29Å; I36-H38 PolarHBondContact O-N 3.25Å; I36-H39 PolarHBondContact O-N 2.96Å; I36-M40 HydrophobicContact CG2-CG 4.11Å; I36-M40 WeakPolarHBondContact O-CB 3.21Å; I36-M40 WeakPolarHBondContact O-CG 3.45Å; I36-M40 PolarHBondContact O-N 3.16Å; I36-F52 HydrophobicContact CG2-CE1 4.48Å; I36-F52 HydrophobicContact CG2-CE2 4.4Å; I36-F52 HydrophobicContact CG2-CZ 3.67Å; I36-V64 HydrophobicContact CD1-CG1 4.07Å; I36-L65 HydrophobicContact CD1-CD2 3.87Å; I36-L65 HydrophobicContact CD1-CG 4.49Å; I36-F68 HydrophobicContact CB-CD1 4.42Å; I36-F68 HydrophobicContact CD1-CB 3.73Å; I36-F68 HydrophobicContact CD1-CD1 4.37Å; I36-F68 HydrophobicContact CD1-CG 4.02Å; I36-F68 HydrophobicContact CG1-CB 3.67Å; I36-F68 HydrophobicContact CG1-CD1 3.39Å; I36-F68 HydrophobicContact CG1-CD2 3.97Å; I36-F68 HydrophobicContact CG1-CE1 3.97Å; I36-F68 HydrophobicContact CG1-CE2 4.49Å; I36-F68 HydrophobicContact CG1-CG 3.39Å; I36-F68 HydrophobicContact CG1-CZ 4.49Å; I36-F88 HydrophobicContact CD1-CE1 4.49Å; I36-F88 HydrophobicContact CD1-CZ 4.21Å; I36-F88 HydrophobicContact CG2-CE1 4.42Å; I36-F93 HydrophobicContact CG2-CZ 4.41Å
37L98Very high96.2Very high1 Ų150.3 Ų50.31%0.00526%0.255CS..Hα-helixtrans-52.7-50.8178.6179.663.1000111.1I30 H39 M40 Q41 F52 V53 P286 Y289I30-L37 WeakPolarHBondContact O-CB 3.1Å; L37-H39 PolarHBondContact O-N 3.22Å; L37-M40 PolarHBondContact O-N 3.47Å; L37-Q41 HydrophobicContact CD1-CG 3.69Å; L37-Q41 HydrophobicContact CG-CG 4.3Å; L37-Q41 WeakPolarHBondContact O-CB 3.48Å; L37-Q41 VanDerWaalsContact O-CG 3.24Å; L37-Q41 WeakPolarHBondContact O-CG 3.47Å; L37-Q41 PolarHBondContact O-N 3.01Å; L37-F52 HydrophobicContact CD1-CD1 3.97Å; L37-F52 HydrophobicContact CD1-CE1 3.92Å; L37-V53 HydrophobicContact CD1-CG1 3.65Å; L37-P286 HydrophobicContact CD1-CB 4.47Å; L37-P286 HydrophobicContact CD2-CB 4.17Å; L37-P286 HydrophobicContact CD2-CG 4.47Å; L37-Y289 HydrophobicContact CD2-CD2 3.88Å; L37-Y289 HydrophobicContact CD2-CE2 3.85Å; L37-Y289 HydrophobicContact CG-CD2 4.1Å; L37-Y289 HydrophobicContact CG-CE2 4.13Å
38H96.9Very high96.1Very high62 Ų6244.5 Ų44.529%0.28724%0.236SC..Hα-helixtrans-57-52.3-177.5-179.463.2000112.4G34 I36 M40 E42 Y289G34-H38 PolarHBondContact O-N 3.07Å; I36-H38 VanDerWaalsContact C-N 3.29Å; I36-H38 PolarHBondContact O-N 3.25Å; H38-M40 PolarHBondContact O-N 3.09Å; H38-E42 IonicContact CD2-OE2 2.87Å; H38-E42 IonicContact CE1-OE1 3.87Å; H38-E42 PolarHBondContact CE1-OE1 3.3Å; H38-E42 IonicContact CE1-OE2 2.67Å; H38-E42 PolarHBondContact CE1-OE2 3.11Å; H38-E42 IonicContact ND1-OE2 2.65Å; H38-E42 IonicContact NE2-OE2 3.74Å; H38-E42 PolarHBondContact NE2-OE2 2.99Å; H38-E42 VanDerWaalsContact NE2-OE2 3.15Å; H38-E42 WeakPolarHBondContact O-CB 3.27Å; H38-E42 WeakPolarHBondContact O-CG 3.5Å; H38-E42 PolarHBondContact O-N 3.34Å; H38-Y289 AromaticContact ND1-CE1 3.95Å; H38-Y289 PolarHBondContact ND1-OH 2.87Å
39H97Very high96Very high53 Ų5343.5 Ų43.525%0.24523%0.228CC..Hα-helixtrans-69.2-35.7-177.9-72.479.1000112.8P35 I36 L37 A43 F68 L85P35-H39 PolarHBondContact O-N 3.26Å; P35-H39 VanDerWaalsContact O-N 3.08Å; P35-H39 PolarHBondContact O-ND1 3.12Å; I36-H39 PolarHBondContact O-N 2.96Å; L37-H39 PolarHBondContact O-N 3.22Å; H39-A43 WeakPolarHBondContact O-CB 3.1Å; H39-A43 PolarHBondContact O-N 3.45Å; H39-A43 VanDerWaalsContact O-N 3.12Å; H39-F68 HydrophobicContact CB-CZ 3.79Å; H39-F68 AromaticContact CG-CZ 3.89Å; H39-L85 HydrophobicContact CB-CD2 4.26Å
40M96.7Very high96Very high3 Ų338 Ų382%0.01520%0.202CC..Hα-helixtrans-67.6-43.5179.1-66-58.7152.200111.5I36 L37 H38 L45 F52 F68 L85 F88 L89I36-M40 HydrophobicContact CG2-CG 4.11Å; I36-M40 WeakPolarHBondContact O-CB 3.21Å; I36-M40 WeakPolarHBondContact O-CG 3.45Å; I36-M40 PolarHBondContact O-N 3.16Å; L37-M40 PolarHBondContact O-N 3.47Å; H38-M40 PolarHBondContact O-N 3.09Å; M40-L45 HydrophobicContact SD-CD1 3.87Å; M40-F52 HydrophobicContact CB-CD1 3.91Å; M40-F52 HydrophobicContact CB-CD2 3.9Å; M40-F52 HydrophobicContact CB-CE1 4.04Å; M40-F52 HydrophobicContact CB-CE2 4.02Å; M40-F52 HydrophobicContact CB-CG 3.86Å; M40-F52 HydrophobicContact CB-CZ 4.1Å; M40-F52 HydrophobicContact CG-CD2 3.95Å; M40-F52 HydrophobicContact CG-CE1 4.24Å; M40-F52 HydrophobicContact CG-CE2 3.64Å; M40-F52 HydrophobicContact CG-CG 4.4Å; M40-F52 HydrophobicContact CG-CZ 3.81Å; M40-F68 HydrophobicContact CE-CD2 4.38Å; M40-F68 HydrophobicContact CE-CE2 3.71Å; M40-F68 HydrophobicContact CE-CZ 4.48Å; M40-L85 HydrophobicContact CE-CB 4.1Å; M40-L85 HydrophobicContact CE-CD2 3.64Å; M40-L85 HydrophobicContact CE-CG 4.43Å; M40-L85 HydrophobicContact SD-CB 4.14Å; M40-L85 HydrophobicContact SD-CD2 4.45Å; M40-F88 HydrophobicContact CE-CD1 3.51Å; M40-F88 HydrophobicContact CE-CE1 4.03Å; M40-F88 HydrophobicContact CE-CG 4.42Å; M40-L89 HydrophobicContact CE-CD2 4.36Å; M40-L89 HydrophobicContact CE-CG 4.36Å; M40-L89 HydrophobicContact CG-CD2 4.31Å; M40-L89 HydrophobicContact SD-CD1 3.87Å; M40-L89 HydrophobicContact SD-CD2 3.71Å; M40-L89 HydrophobicContact SD-CG 3.66Å
41Q97Very high96Very high4 Ų441 Ų412%0.01922%0.216CC..Hα-helixtrans-71.9-49.4-179.9-61.8-6641.600111.4L37 A43 K44 D49 P286 Y289 T290L37-Q41 HydrophobicContact CD1-CG 3.69Å; L37-Q41 HydrophobicContact CG-CG 4.3Å; L37-Q41 WeakPolarHBondContact O-CB 3.48Å; L37-Q41 VanDerWaalsContact O-CG 3.24Å; L37-Q41 WeakPolarHBondContact O-CG 3.47Å; L37-Q41 PolarHBondContact O-N 3.01Å; Q41-A43 PolarHBondContact O-N 3.09Å; Q41-K44 WeakPolarHBondContact O-CA 3.42Å; Q41-K44 PolarHBondContact O-N 3.07Å; Q41-D49 PolarHBondContact NE2-O 3.35Å; Q41-P286 PolarHBondContact NE2-O 2.86Å; Q41-Y289 HydrophobicContact CB-CD1 3.47Å; Q41-Y289 VanDerWaalsContact CB-CD1 3.47Å; Q41-Y289 HydrophobicContact CB-CE1 4.23Å; Q41-Y289 HydrophobicContact CB-CG 3.99Å; Q41-Y289 HydrophobicContact CG-CD1 3.89Å; Q41-Y289 HydrophobicContact CG-CG 3.9Å; Q41-T290 VanDerWaalsContact C-CG2 3.48Å; Q41-T290 HydrophobicContact CB-CG2 3.95Å; Q41-T290 WeakPolarHBondContact O-CG2 3.46Å
42E95.6Very high96Very high110 Ų11040.9 Ų40.951%0.51422%0.215SC..Hα-helixtrans-63.5-29179.2-73.8-159.8136.500113.5H38 K44 L293H38-E42 IonicContact CD2-OE2 2.87Å; H38-E42 IonicContact CE1-OE1 3.87Å; H38-E42 PolarHBondContact CE1-OE1 3.3Å; H38-E42 IonicContact CE1-OE2 2.67Å; H38-E42 PolarHBondContact CE1-OE2 3.11Å; H38-E42 IonicContact ND1-OE2 2.65Å; H38-E42 IonicContact NE2-OE2 3.74Å; H38-E42 PolarHBondContact NE2-OE2 2.99Å; H38-E42 VanDerWaalsContact NE2-OE2 3.15Å; H38-E42 WeakPolarHBondContact O-CB 3.27Å; H38-E42 WeakPolarHBondContact O-CG 3.5Å; H38-E42 PolarHBondContact O-N 3.34Å; E42-K44 PolarHBondContact O-N 3.34Å; E42-L293 HydrophobicContact CG-CD1 4.4Å
43A95.6Very high96Very high14 Ų1440.8 Ų40.812%0.11622%0.215CC..THydrogen-bonded Turntrans-68-13.5173.600000113H39 Q41 L45 K82 L85H39-A43 WeakPolarHBondContact O-CB 3.1Å; H39-A43 PolarHBondContact O-N 3.45Å; H39-A43 VanDerWaalsContact O-N 3.12Å; Q41-A43 PolarHBondContact O-N 3.09Å; A43-L45 VanDerWaalsContact C-N 3.26Å; A43-L45 HydrophobicContact CB-CD2 3.89Å; A43-L45 HydrophobicContact CB-CG 3.87Å; A43-L45 PolarHBondContact O-N 2.91Å; A43-K82 WeakPolarHBondContact O-CE 3.38Å; A43-K82 PolarHBondContact O-NZ 2.63Å; A43-L85 HydrophobicContact CB-CD1 3.47Å; A43-L85 VanDerWaalsContact CB-CD1 3.47Å
44K95.4Very high96.1Very high99 Ų9939.7 Ų39.743%0.4321%0.207SC..THydrogen-bonded Turntrans45.852.2-178.4-60.4-170.7177.9-164.30111.1Q41 E42 F46 T290 E294Q41-K44 WeakPolarHBondContact O-CA 3.42Å; Q41-K44 PolarHBondContact O-N 3.07Å; E42-K44 PolarHBondContact O-N 3.34Å; K44-F46 PolarHBondContact O-N 2.87Å; K44-T290 HydrophobicContact CG-CG2 4.39Å; K44-E294 WeakPolarHBondContact CE-OE1 3.44Å; K44-E294 IonicContact NZ-OE1 3.93Å; K44-E294 PolarHBondContact NZ-OE1 3.43Å; K44-E294 IonicContact NZ-OE2 2.85Å
45L95Very high96.2Very high30 Ų3038.8 Ų38.816%0.15719%0.194CC..  trans-70-22.8179.5-60.3-178.8000111.8M40 A43 K82 L85 E86 L89M40-L45 HydrophobicContact SD-CD1 3.87Å; A43-L45 VanDerWaalsContact C-N 3.26Å; A43-L45 HydrophobicContact CB-CD2 3.89Å; A43-L45 HydrophobicContact CB-CG 3.87Å; A43-L45 PolarHBondContact O-N 2.91Å; L45-K82 HydrophobicContact CD2-CB 4.06Å; L45-K82 HydrophobicContact CD2-CD 4.22Å; L45-K82 HydrophobicContact CD2-CG 4.22Å; L45-L85 HydrophobicContact CD1-CB 3.86Å; L45-E86 HydrophobicContact CD1-CG 4.5Å; L45-E86 HydrophobicContact CD2-CG 4.11Å; L45-L89 HydrophobicContact CD1-CD1 3.57Å
46F94.6Very high96.3Very high60 Ų6038.4 Ų38.426%0.26319%0.187SC..SBendtrans-126.1155.8175.7-52.2-70.7000109.4K44 D48 H51 F52 M55 L89K44-F46 PolarHBondContact O-N 2.87Å; F46-D48 PolarHBondContact O-N 2.91Å; F46-H51 HydrophobicContact CB-CB 3.78Å; F46-H51 HydrophobicContact CD1-CB 4.38Å; F46-H51 AromaticContact CD1-CD2 3.45Å; F46-H51 VanDerWaalsContact CD1-CD2 3.45Å; F46-H51 WeakPolarHBondContact CD1-CD2 3.43Å; F46-H51 AromaticContact CD1-CG 3.76Å; F46-H51 AromaticContact CD1-NE2 3.76Å; F46-H51 HydrophobicContact CD2-CB 4.01Å; F46-H51 AromaticContact CD2-CD2 3.61Å; F46-H51 AromaticContact CE1-CD2 3.4Å; F46-H51 VanDerWaalsContact CE1-CD2 3.4Å; F46-H51 WeakPolarHBondContact CE1-CD2 3.31Å; F46-H51 AromaticContact CE1-NE2 3.45Å; F46-H51 WeakPolarHBondContact CE1-NE2 3.36Å; F46-H51 AromaticContact CE2-CD2 3.56Å; F46-H51 HydrophobicContact CG-CB 3.79Å; F46-H51 AromaticContact CG-CD2 3.55Å; F46-H51 AromaticContact CG-CG 3.66Å; F46-H51 AromaticContact CZ-CD2 3.46Å; F46-H51 VanDerWaalsContact CZ-CD2 3.46Å; F46-H51 WeakPolarHBondContact CZ-CD2 3.22Å; F46-H51 AromaticContact CZ-NE2 3.77Å; F46-F52 HydrophobicContact CD2-CB 4.31Å; F46-F52 HydrophobicContact CE2-CB 4.35Å; F46-M55 HydrophobicContact CE2-SD 4.18Å; F46-M55 HydrophobicContact CZ-SD 4.23Å; F46-L89 HydrophobicContact CE2-CD1 3.85Å; F46-L89 HydrophobicContact CZ-CD1 3.97Å
47N92.1Very high96.3Very high181 Ų18138.4 Ų38.497%0.96819%0.188SC*.SBendtrans-76.2-12.8176.6-66.6-16.8000113.3
48D93.1Very high96.3Very high52 Ų5242.8 Ų42.828%0.27821%0.206SC..SBendtrans-130.5117.6-178.3179.9-6.3000107.9F46 K50 H51 R167F46-D48 PolarHBondContact O-N 2.91Å; D48-K50 PolarHBondContact O-N 3.4Å; D48-K50 WeakPolarHBondContact OD1-CB 3.41Å; D48-K50 PolarHBondContact OD1-N 2.91Å; D48-H51 WeakPolarHBondContact O-CB 3.35Å; D48-H51 PolarHBondContact O-N 3.37Å; D48-R167 IonicContact OD1-CZ 2.76Å; D48-R167 IonicContact OD1-NE 3.1Å; D48-R167 IonicContact OD1-NH2 2.67Å; D48-R167 PolarHBondContact OD1-NH2 3.25Å; D48-R167 IonicContact OD2-CZ 3.41Å; D48-R167 IonicContact OD2-NE 3.8Å; D48-R167 PolarHBondContact OD2-NE 3.09Å; D48-R167 IonicContact OD2-NH2 3.51Å; D48-R167 PolarHBondContact OD2-NH2 3.12Å
49D95.4Very high96.3Very high11 Ų1141.6 Ų41.66%0.05921%0.205CC..THydrogen-bonded Turntrans-58.9-27-179.9-78.72.4000112.4Q41 H51 E287 Y289 T290Q41-D49 PolarHBondContact NE2-O 3.35Å; D49-H51 PolarHBondContact O-N 2.94Å; D49-E287 WeakPolarHBondContact CB-O 3.43Å; D49-Y289 PolarHBondContact OD2-N 3.32Å; D49-T290 PolarHBondContact OD1-OG1 2.9Å; D49-T290 WeakPolarHBondContact OD2-CB 3.45Å; D49-T290 PolarHBondContact OD2-N 2.92Å; D49-T290 PolarHBondContact OD2-OG1 3.39Å
50K96.6Very high96.4Very high2 Ų242 Ų421%0.00921%0.212CC..Hα-helixtrans-63.8-22.9174.4-167.9172.2-171.3-69.70112.6D48 F52 V53 D54 R167 E170 Y216 E287D48-K50 PolarHBondContact O-N 3.4Å; D48-K50 WeakPolarHBondContact OD1-CB 3.41Å; D48-K50 PolarHBondContact OD1-N 2.91Å; K50-F52 PolarHBondContact O-N 3.07Å; K50-V53 HydrophobicContact CG-CG2 4.48Å; K50-V53 WeakPolarHBondContact O-CG2 3.49Å; K50-D54 IonicContact NZ-OD1 3.82Å; K50-D54 IonicContact NZ-OD2 3.8Å; K50-D54 PolarHBondContact NZ-OD2 3.13Å; K50-D54 WeakPolarHBondContact O-CB 3.5Å; K50-D54 VanDerWaalsContact O-CG 3.3Å; K50-D54 PolarHBondContact O-N 3.32Å; K50-D54 VanDerWaalsContact O-N 3.14Å; K50-R167 PolarHBondContact NZ-O 2.63Å; K50-E170 WeakPolarHBondContact CE-OE1 3.14Å; K50-E170 VanDerWaalsContact NZ-CD 3.34Å; K50-E170 IonicContact NZ-OE1 2.71Å; K50-E170 PolarHBondContact NZ-OE1 3.16Å; K50-E170 IonicContact NZ-OE2 3.98Å; K50-E170 PolarHBondContact NZ-OE2 3.13Å; K50-E170 VanDerWaalsContact NZ-OE2 3.16Å; K50-Y216 WeakPolarHBondContact CE-OH 3.22Å; K50-E287 HydrophobicContact CB-CB 4.21Å; K50-E287 HydrophobicContact CG-CB 4.23Å; K50-E287 PolarHBondContact N-O 3.25Å
51H96.6Very high96.4Very high64 Ų6443.5 Ų43.530%0.29622%0.222SC..Hα-helixtrans-59.3-50.3-179.5-168.8101.5000111.9F46 D48 D49 D54 M55 P96F46-H51 HydrophobicContact CB-CB 3.78Å; F46-H51 HydrophobicContact CD1-CB 4.38Å; F46-H51 AromaticContact CD1-CD2 3.45Å; F46-H51 VanDerWaalsContact CD1-CD2 3.45Å; F46-H51 WeakPolarHBondContact CD1-CD2 3.43Å; F46-H51 AromaticContact CD1-CG 3.76Å; F46-H51 AromaticContact CD1-NE2 3.76Å; F46-H51 HydrophobicContact CD2-CB 4.01Å; F46-H51 AromaticContact CD2-CD2 3.61Å; F46-H51 AromaticContact CE1-CD2 3.4Å; F46-H51 VanDerWaalsContact CE1-CD2 3.4Å; F46-H51 WeakPolarHBondContact CE1-CD2 3.31Å; F46-H51 AromaticContact CE1-NE2 3.45Å; F46-H51 WeakPolarHBondContact CE1-NE2 3.36Å; F46-H51 AromaticContact CE2-CD2 3.56Å; F46-H51 HydrophobicContact CG-CB 3.79Å; F46-H51 AromaticContact CG-CD2 3.55Å; F46-H51 AromaticContact CG-CG 3.66Å; F46-H51 AromaticContact CZ-CD2 3.46Å; F46-H51 VanDerWaalsContact CZ-CD2 3.46Å; F46-H51 WeakPolarHBondContact CZ-CD2 3.22Å; F46-H51 AromaticContact CZ-NE2 3.77Å; D48-H51 WeakPolarHBondContact O-CB 3.35Å; D48-H51 PolarHBondContact O-N 3.37Å; D49-H51 PolarHBondContact O-N 2.94Å; H51-D54 PolarHBondContact O-N 2.83Å; H51-M55 WeakPolarHBondContact O-CG 3.27Å; H51-M55 PolarHBondContact O-N 3.49Å; H51-P96 VanDerWaalsContact O-CG 3.25Å; H51-P96 WeakPolarHBondContact O-CG 3.33Å
52F97.9Very high96.5Very high1 Ų145.8 Ų45.80%0.00425%0.248CC..Hα-helixtrans-66.7-46.5-177.1169.7-106.7000111.5I30 I36 L37 M40 F46 K50 D54 M55 L89 F93I30-F52 HydrophobicContact CG2-CZ 4.38Å; I36-F52 HydrophobicContact CG2-CE1 4.48Å; I36-F52 HydrophobicContact CG2-CE2 4.4Å; I36-F52 HydrophobicContact CG2-CZ 3.67Å; L37-F52 HydrophobicContact CD1-CD1 3.97Å; L37-F52 HydrophobicContact CD1-CE1 3.92Å; M40-F52 HydrophobicContact CB-CD1 3.91Å; M40-F52 HydrophobicContact CB-CD2 3.9Å; M40-F52 HydrophobicContact CB-CE1 4.04Å; M40-F52 HydrophobicContact CB-CE2 4.02Å; M40-F52 HydrophobicContact CB-CG 3.86Å; M40-F52 HydrophobicContact CB-CZ 4.1Å; M40-F52 HydrophobicContact CG-CD2 3.95Å; M40-F52 HydrophobicContact CG-CE1 4.24Å; M40-F52 HydrophobicContact CG-CE2 3.64Å; M40-F52 HydrophobicContact CG-CG 4.4Å; M40-F52 HydrophobicContact CG-CZ 3.81Å; F46-F52 HydrophobicContact CD2-CB 4.31Å; F46-F52 HydrophobicContact CE2-CB 4.35Å; K50-F52 PolarHBondContact O-N 3.07Å; F52-D54 PolarHBondContact O-N 2.98Å; F52-D54 VanDerWaalsContact O-N 3.16Å; F52-M55 HydrophobicContact CD2-SD 4Å; F52-M55 VanDerWaalsContact O-CB 3.3Å; F52-M55 WeakPolarHBondContact O-CB 3.46Å; F52-M55 WeakPolarHBondContact O-CG 3.44Å; F52-M55 PolarHBondContact O-N 3.36Å; F52-L89 HydrophobicContact CD2-CD2 3.76Å; F52-L89 HydrophobicContact CE2-CD2 3.6Å; F52-F93 HydrophobicContact CE2-CD1 4.34Å; F52-F93 AromaticContact CE2-CE1 3.78Å; F52-F93 HydrophobicContact CE2-CE1 3.78Å; F52-F93 HydrophobicContact CE2-CE2 4.4Å; F52-F93 AromaticContact CE2-CZ 3.84Å; F52-F93 HydrophobicContact CE2-CZ 3.84Å; F52-F93 HydrophobicContact CZ-CE1 4.1Å; F52-F93 HydrophobicContact CZ-CZ 4.06Å
53V97.5Very high96.6Very high0 Ų046.1 Ų46.10%025%0.249CC..Hα-helixtrans-70.3-11.6-177.5-62.60000113.6L37 K50 S153 Y216 P286 E287L37-V53 HydrophobicContact CD1-CG1 3.65Å; K50-V53 HydrophobicContact CG-CG2 4.48Å; K50-V53 WeakPolarHBondContact O-CG2 3.49Å; V53-S153 WeakPolarHBondContact O-CB 3.12Å; V53-S153 PolarHBondContact O-OG 3.31Å; V53-Y216 HydrophobicContact CB-CD1 4.05Å; V53-Y216 HydrophobicContact CB-CE1 3.83Å; V53-Y216 HydrophobicContact CG2-CD1 4.16Å; V53-Y216 HydrophobicContact CG2-CE1 3.63Å; V53-P286 HydrophobicContact CG1-CB 3.9Å; V53-P286 WeakPolarHBondContact CG1-O 3.46Å; V53-E287 HydrophobicContact CG2-CB 4.16Å
54D97.6Very high96.8Very high6 Ų645.5 Ų45.53%0.03224%0.244CC..THydrogen-bonded Turntrans-95.5-4.8172.4-74.1-1.3000113.8K50 H51 F52 P96 R214 Y216K50-D54 IonicContact NZ-OD1 3.82Å; K50-D54 IonicContact NZ-OD2 3.8Å; K50-D54 PolarHBondContact NZ-OD2 3.13Å; K50-D54 WeakPolarHBondContact O-CB 3.5Å; K50-D54 VanDerWaalsContact O-CG 3.3Å; K50-D54 PolarHBondContact O-N 3.32Å; K50-D54 VanDerWaalsContact O-N 3.14Å; H51-D54 PolarHBondContact O-N 2.83Å; F52-D54 PolarHBondContact O-N 2.98Å; F52-D54 VanDerWaalsContact O-N 3.16Å; D54-P96 HydrophobicContact CB-CB 3.87Å; D54-P96 HydrophobicContact CB-CG 4.15Å; D54-R214 IonicContact OD1-CZ 2.67Å; D54-R214 IonicContact OD1-NE 3.21Å; D54-R214 PolarHBondContact OD1-NE 3.45Å; D54-R214 IonicContact OD1-NH1 3.48Å; D54-R214 IonicContact OD1-NH2 3.23Å; D54-R214 IonicContact OD2-CZ 3.26Å; D54-R214 IonicContact OD2-NH2 2.8Å; D54-Y216 PolarHBondContact OD1-OH 2.8Å
55M97.9Very high96.9Very high12 Ų1243 Ų436%0.05924%0.235CC..PPolyproline II helixtrans-66.7152.9174-60.9-176.182.600110.6Y31 F46 H51 F52 L89 F93 D94 P96Y31-M55 WeakPolarHBondContact CE1-O 3.42Å; Y31-M55 PolarHBondContact OH-O 3.25Å; F46-M55 HydrophobicContact CE2-SD 4.18Å; F46-M55 HydrophobicContact CZ-SD 4.23Å; H51-M55 WeakPolarHBondContact O-CG 3.27Å; H51-M55 PolarHBondContact O-N 3.49Å; F52-M55 HydrophobicContact CD2-SD 4Å; F52-M55 VanDerWaalsContact O-CB 3.3Å; F52-M55 WeakPolarHBondContact O-CB 3.46Å; F52-M55 WeakPolarHBondContact O-CG 3.44Å; F52-M55 PolarHBondContact O-N 3.36Å; M55-L89 HydrophobicContact SD-CD2 4.14Å; M55-F93 HydrophobicContact CB-CB 4.12Å; M55-F93 HydrophobicContact CB-CD1 3.7Å; M55-F93 HydrophobicContact CB-CG 4.33Å; M55-F93 HydrophobicContact CE-CB 3.54Å; M55-F93 HydrophobicContact CE-CG 4.46Å; M55-F93 HydrophobicContact SD-CB 4.19Å; M55-D94 WeakPolarHBondContact CB-O 3.09Å; M55-P96 HydrophobicContact CG-CG 3.95Å
56K97.1Very high97.1Very high41 Ų4144.2 Ų44.218%0.17825%0.249CC..EExtended strand (participates in β ladder)trans-103.4141.5177.2166.5-155.3165.4-1550109.3F93 D94 Y152K56-F93 CarbonylContact O-C 3.09Å; K56-F93 WeakPolarHBondContact O-CA 3.41Å; K56-D94 HydrophobicContact CB-CB 4.2Å; K56-D94 HydrophobicContact CD-CB 4.17Å; K56-D94 PolarHBondContact N-O 3.48Å; K56-D94 IonicContact NZ-OD2 3.94Å; K56-D94 PolarHBondContact NZ-OD2 3.34Å; K56-D94 PolarHBondContact O-N 2.97Å; K56-Y152 HydrophobicContact CB-CD1 4.08Å; K56-Y152 HydrophobicContact CB-CE1 4.2Å; K56-Y152 HydrophobicContact CD-CD1 4.16Å; K56-Y152 HydrophobicContact CD-CE1 3.42Å; K56-Y152 VanDerWaalsContact CD-CE1 3.42Å; K56-Y152 VanDerWaalsContact CE-OH 3.29Å; K56-Y152 WeakPolarHBondContact CE-OH 3.17Å; K56-Y152 HydrophobicContact CG-CD1 3.7Å; K56-Y152 HydrophobicContact CG-CE1 3.46Å; K56-Y152 VanDerWaalsContact CG-CE1 3.46Å; K56-Y152 HydrophobicContact CG-CG 4.45Å
57L98.4Very high97.2Very high1 Ų143.1 Ų43.11%0.00525%0.252CS..EExtended strand (participates in β ladder)trans-71.8141.1172.1-52.9-178.5000112.2I30 Y31 S59 P61 V64 F93 L151I30-L57 HydrophobicContact CD1-CD1 3.82Å; I30-L57 HydrophobicContact CD1-CD2 4.21Å; I30-L57 HydrophobicContact CG2-CD2 4.29Å; Y31-L57 WeakPolarHBondContact OH-CG 3.38Å; Y31-L57 PolarHBondContact OH-N 3.37Å; L57-S59 VanDerWaalsContact CB-O 3.32Å; L57-S59 WeakPolarHBondContact CB-O 3.29Å; L57-P61 HydrophobicContact CD1-CB 4.18Å; L57-P61 HydrophobicContact CD1-CG 3.72Å; L57-V64 HydrophobicContact CD2-CG1 4.37Å; L57-V64 HydrophobicContact CD2-CG2 4.35Å; L57-F93 HydrophobicContact CD2-CD1 3.7Å; L57-F93 HydrophobicContact CD2-CE1 3.18Å; L57-F93 HydrophobicContact CD2-CE2 4.25Å; L57-F93 HydrophobicContact CD2-CG 4.45Å; L57-F93 HydrophobicContact CD2-CZ 3.48Å; L57-F93 VanDerWaalsContact CD2-CZ 3.48Å; L57-L151 HydrophobicContact CB-CB 4.24Å; L57-L151 HydrophobicContact CB-CD2 3.97Å; L57-L151 PolarHBondContact N-O 2.93Å
58K98.1Very high97.5Very high92 Ų9234.6 Ų34.640%0.421%0.206SC..SBendtrans-82.3-24171.7-70.4175.9171.5168.90113.1E90 A91 N92 F93 D94K58-E90 PolarHBondContact NZ-O 2.82Å; K58-A91 WeakPolarHBondContact CD-O 3.5Å; K58-N92 WeakPolarHBondContact CB-O 3.13Å; K58-N92 PolarHBondContact N-O 3.02Å; K58-F93 VanDerWaalsContact CE-C 3.49Å; K58-F93 WeakPolarHBondContact CE-O 3.49Å; K58-F93 PolarHBondContact NZ-O 3.04Å; K58-D94 WeakPolarHBondContact CE-OD1 3.44Å
59S97.8Very high97.7Very high38 Ų3836.7 Ų36.727%0.26621%0.214SC..SBendtrans-137.3162.1-178.4-670000111L57 L151L57-S59 VanDerWaalsContact CB-O 3.32Å; L57-S59 WeakPolarHBondContact CB-O 3.29Å; S59-L151 VanDerWaalsContact C-CD2 3.49Å; S59-L151 VanDerWaalsContact O-CD2 3.24Å; S59-L151 WeakPolarHBondContact O-CD2 3.42Å
60P98Very high97.8Very high60 Ų6039.9 Ų39.939%0.3923%0.234SC..  trans-52.2146.1178-27.935.9000113.3G62 E63 V64P60-G62 PolarHBondContact O-N 2.92Å; P60-E63 PolarHBondContact O-N 3.29Å; P60-V64 PolarHBondContact O-N 2.88Å
61P97.9Very high97.8Very high35 Ų3540.5 Ų40.523%0.22724%0.237CC..Hα-helixtrans-50.9-38-176.2-29.833.9000114.7I30 L57 E63 V64 L65 E150I30-P61 HydrophobicContact CD1-CB 3.89Å; L57-P61 HydrophobicContact CD1-CB 4.18Å; L57-P61 HydrophobicContact CD1-CG 3.72Å; P61-E63 VanDerWaalsContact C-N 3.32Å; P61-E63 PolarHBondContact O-N 3.47Å; P61-V64 PolarHBondContact O-N 2.89Å; P61-L65 WeakPolarHBondContact O-CB 3.44Å; P61-L65 WeakPolarHBondContact O-CD1 3.47Å; P61-L65 WeakPolarHBondContact O-CG 3.5Å; P61-L65 PolarHBondContact O-N 2.96Å; P61-E150 HydrophobicContact CG-CB 3.97Å; P61-E150 HydrophobicContact CG-CG 4.19Å; P61-E150 VanDerWaalsContact CG-O 3.28Å; P61-E150 WeakPolarHBondContact CG-O 3.3Å
62G98.2Very high97.7Very high53 Ų5339 Ų3955%0.54623%0.231SC..Hα-helixtrans-62.1-36.2179.300000113.7P60 A66P60-G62 PolarHBondContact O-N 2.92Å; G62-A66 WeakPolarHBondContact O-CB 3.31Å; G62-A66 PolarHBondContact O-N 2.74Å
63E98.4Very high97.5Very high117 Ų11743 Ų4355%0.54725%0.252SS..Hα-helixtrans-71.3-43.2176.2-68179.3-149.200111.1P60 P61 A66 A67P60-E63 PolarHBondContact O-N 3.29Å; P61-E63 VanDerWaalsContact C-N 3.32Å; P61-E63 PolarHBondContact O-N 3.47Å; E63-A66 PolarHBondContact O-N 3.45Å; E63-A67 WeakPolarHBondContact O-CB 3.39Å; E63-A67 PolarHBondContact O-N 3.45Å
64V98.6Very high97.4Very high0 Ų049.2 Ų49.20%028%0.282CS..Hα-helixtrans-64.7-42.4178.7-179.50000110.9I30 I36 L57 P60 P61 A67 F68 F88 N92 F93I30-V64 HydrophobicContact CD1-CB 4.29Å; I30-V64 HydrophobicContact CD1-CG1 4.26Å; I36-V64 HydrophobicContact CD1-CG1 4.07Å; L57-V64 HydrophobicContact CD2-CG1 4.37Å; L57-V64 HydrophobicContact CD2-CG2 4.35Å; P60-V64 PolarHBondContact O-N 2.88Å; P61-V64 PolarHBondContact O-N 2.89Å; V64-A67 PolarHBondContact O-N 3.18Å; V64-F68 PolarHBondContact O-N 3.41Å; V64-F88 HydrophobicContact CG1-CE1 4.35Å; V64-F88 HydrophobicContact CG1-CZ 3.74Å; V64-N92 HydrophobicContact CG1-CB 4.03Å; V64-N92 HydrophobicContact CG2-CB 4.25Å; V64-F93 HydrophobicContact CG1-CE2 3.98Å; V64-F93 HydrophobicContact CG1-CZ 4.16Å
65L98.5Very high97.1Very high46 Ų4652.5 Ų52.524%0.24129%0.294CS..Hα-helixtrans-62.4-43.3174.3-73165.3000111.6E29 I30 I36 P61 F68 Q69E29-L65 HydrophobicContact CB-CD2 4.36Å; I30-L65 HydrophobicContact CD1-CD2 4.49Å; I30-L65 HydrophobicContact CD1-CG 4.16Å; I30-L65 HydrophobicContact CG1-CD2 3.97Å; I30-L65 HydrophobicContact CG1-CG 4.14Å; I36-L65 HydrophobicContact CD1-CD2 3.87Å; I36-L65 HydrophobicContact CD1-CG 4.49Å; P61-L65 WeakPolarHBondContact O-CB 3.44Å; P61-L65 WeakPolarHBondContact O-CD1 3.47Å; P61-L65 WeakPolarHBondContact O-CG 3.5Å; P61-L65 PolarHBondContact O-N 2.96Å; L65-F68 PolarHBondContact O-N 3.34Å; L65-Q69 WeakPolarHBondContact O-CB 3.35Å; L65-Q69 PolarHBondContact O-N 2.92Å
66A98.3Very high96.5Very high56 Ų5658 Ų5846%0.46332%0.323SS..Hα-helixtrans-66-39.9176.900000112.5G62 E63 F68 Q69 T70G62-A66 WeakPolarHBondContact O-CB 3.31Å; G62-A66 PolarHBondContact O-N 2.74Å; E63-A66 PolarHBondContact O-N 3.45Å; A66-F68 VanDerWaalsContact C-N 3.34Å; A66-Q69 PolarHBondContact O-N 3.37Å; A66-T70 PolarHBondContact O-N 2.85Å; A66-T70 PolarHBondContact O-OG1 2.91Å
67A97.9Very high95.9Very high38 Ų3864 Ų6431%0.31436%0.357SS..Hα-helixtrans-62-43.117400000111E63 V64 T70 L71 F88E63-A67 WeakPolarHBondContact O-CB 3.39Å; E63-A67 PolarHBondContact O-N 3.45Å; V64-A67 PolarHBondContact O-N 3.18Å; A67-T70 WeakPolarHBondContact O-CB 3.42Å; A67-T70 PolarHBondContact O-N 2.95Å; A67-L71 PolarHBondContact O-N 3.09Å; A67-L71 VanDerWaalsContact O-N 3.11Å; A67-F88 HydrophobicContact CB-CE2 3.97Å
68F97.9Very high95.4Very high2 Ų267.1 Ų67.11%0.00938%0.378CS..Hα-helixtrans-68.8-37.4177.3-163-108.6000112.6P35 I36 H39 M40 V64 L65 A66 T70 L71 L72 I80 L85 F88P35-F68 HydrophobicContact CB-CD1 4.45Å; P35-F68 HydrophobicContact CB-CE1 4.08Å; P35-F68 HydrophobicContact CG-CD1 4.42Å; I36-F68 HydrophobicContact CB-CD1 4.42Å; I36-F68 HydrophobicContact CD1-CB 3.73Å; I36-F68 HydrophobicContact CD1-CD1 4.37Å; I36-F68 HydrophobicContact CD1-CG 4.02Å; I36-F68 HydrophobicContact CG1-CB 3.67Å; I36-F68 HydrophobicContact CG1-CD1 3.39Å; I36-F68 HydrophobicContact CG1-CD2 3.97Å; I36-F68 HydrophobicContact CG1-CE1 3.97Å; I36-F68 HydrophobicContact CG1-CE2 4.49Å; I36-F68 HydrophobicContact CG1-CG 3.39Å; I36-F68 HydrophobicContact CG1-CZ 4.49Å; H39-F68 HydrophobicContact CB-CZ 3.79Å; H39-F68 AromaticContact CG-CZ 3.89Å; M40-F68 HydrophobicContact CE-CD2 4.38Å; M40-F68 HydrophobicContact CE-CE2 3.71Å; M40-F68 HydrophobicContact CE-CZ 4.48Å; V64-F68 PolarHBondContact O-N 3.41Å; L65-F68 PolarHBondContact O-N 3.34Å; A66-F68 VanDerWaalsContact C-N 3.34Å; F68-T70 PolarHBondContact O-N 3.22Å; F68-L71 HydrophobicContact CD2-CD2 4.09Å; F68-L71 HydrophobicContact CE2-CD2 3.97Å; F68-L71 WeakPolarHBondContact O-CB 3.49Å; F68-L71 PolarHBondContact O-N 3.18Å; F68-L71 VanDerWaalsContact O-N 3.12Å; F68-L72 HydrophobicContact CD1-CD1 3.68Å; F68-L72 HydrophobicContact CD1-CG 3.94Å; F68-L72 HydrophobicContact CE1-CD1 3.72Å; F68-L72 HydrophobicContact CE1-CD2 4Å; F68-L72 HydrophobicContact CE1-CG 3.77Å; F68-L72 HydrophobicContact CZ-CD2 4.47Å; F68-L72 HydrophobicContact CZ-CG 4.47Å; F68-L72 WeakPolarHBondContact O-CG 3.4Å; F68-L72 PolarHBondContact O-N 2.93Å; F68-I80 HydrophobicContact CZ-CD1 4.23Å; F68-L85 HydrophobicContact CE2-CD2 3.93Å; F68-L85 HydrophobicContact CZ-CD2 4.3Å; F68-F88 HydrophobicContact CB-CE1 4.43Å; F68-F88 HydrophobicContact CB-CE2 3.74Å; F68-F88 HydrophobicContact CB-CZ 3.61Å; F68-F88 AromaticContact CD2-CD1 3.95Å; F68-F88 HydrophobicContact CD2-CD1 3.95Å; F68-F88 HydrophobicContact CD2-CD2 4.06Å; F68-F88 AromaticContact CD2-CE1 3.67Å; F68-F88 HydrophobicContact CD2-CE1 3.67Å; F68-F88 AromaticContact CD2-CE2 3.83Å; F68-F88 HydrophobicContact CD2-CE2 3.83Å; F68-F88 HydrophobicContact CD2-CG 4.13Å; F68-F88 AromaticContact CD2-CZ 3.63Å; F68-F88 HydrophobicContact CD2-CZ 3.63Å; F68-F88 HydrophobicContact CE2-CD1 4.4Å; F68-F88 HydrophobicContact CE2-CE1 4.4Å; F68-F88 HydrophobicContact CG-CE1 4.42Å; F68-F88 HydrophobicContact CG-CE2 4.3Å; F68-F88 HydrophobicContact CG-CZ 4.05Å
69Q97.4Very high95Very high96 Ų9667.7 Ų67.745%0.44939%0.394SS..Hα-helixtrans-61.3-35.8174-173.259.845.700111.6L65 A66 L72 N73L65-Q69 WeakPolarHBondContact O-CB 3.35Å; L65-Q69 PolarHBondContact O-N 2.92Å; A66-Q69 PolarHBondContact O-N 3.37Å; Q69-L72 PolarHBondContact O-N 3.41Å; Q69-N73 PolarHBondContact NE2-OD1 3.45Å; Q69-N73 WeakPolarHBondContact O-CB 3.45Å; Q69-N73 PolarHBondContact O-N 2.91Å; Q69-N73 PolarHBondContact O-ND2 3.27Å; Q69-N73 PolarHBondContact O-OD1 3.06Å
70T96.9Very high94.9Very high77 Ų7766.7 Ų66.747%0.47239%0.385SS..Hα-helixtrans-63.6-45.6173.2-56.40000110.8A66 A67 F68 L72 N73 E74A66-T70 PolarHBondContact O-N 2.85Å; A66-T70 PolarHBondContact O-OG1 2.91Å; A67-T70 WeakPolarHBondContact O-CB 3.42Å; A67-T70 PolarHBondContact O-N 2.95Å; F68-T70 PolarHBondContact O-N 3.22Å; T70-L72 PolarHBondContact O-N 2.93Å; T70-N73 WeakPolarHBondContact O-CB 3.45Å; T70-N73 PolarHBondContact O-N 3.44Å; T70-E74 PolarHBondContact O-N 3.28Å; T70-E74 VanDerWaalsContact O-N 3.15Å
71L96.5Very high94.8Very high16 Ų1665.8 Ų65.88%0.08438%0.38CS..Hα-helixtrans-60.5-43.2175179.861.9000112.2A67 F68 N73 E74 W75 I80 K84 L85 F88A67-L71 PolarHBondContact O-N 3.09Å; A67-L71 VanDerWaalsContact O-N 3.11Å; F68-L71 HydrophobicContact CD2-CD2 4.09Å; F68-L71 HydrophobicContact CE2-CD2 3.97Å; F68-L71 WeakPolarHBondContact O-CB 3.49Å; F68-L71 PolarHBondContact O-N 3.18Å; F68-L71 VanDerWaalsContact O-N 3.12Å; L71-N73 VanDerWaalsContact C-N 3.3Å; L71-N73 PolarHBondContact O-N 3.35Å; L71-E74 PolarHBondContact O-N 2.99Å; L71-W75 PolarHBondContact O-N 3.27Å; L71-I80 HydrophobicContact CD1-CG2 4.26Å; L71-I80 HydrophobicContact CD2-CD1 4.32Å; L71-I80 HydrophobicContact CD2-CG2 4.18Å; L71-I80 HydrophobicContact CG-CD1 4.1Å; L71-I80 HydrophobicContact CG-CG2 4.27Å; L71-K84 HydrophobicContact CD1-CB 4.19Å; L71-L85 HydrophobicContact CD2-CD2 4.32Å; L71-F88 HydrophobicContact CD2-CB 4.06Å; L71-F88 HydrophobicContact CD2-CD2 4.35Å; L71-F88 HydrophobicContact CD2-CG 4.3Å
72L95.1Very high94.7Very high32 Ų3269.5 Ų69.517%0.16839%0.392CS..Hα-helixtrans-60.2-40.7175-74.9168.7000111.8P35 F68 Q69 T70 E74 W75 L76 I80P35-L72 HydrophobicContact CB-CD1 4.09Å; P35-L72 HydrophobicContact CG-CD1 4.33Å; F68-L72 HydrophobicContact CD1-CD1 3.68Å; F68-L72 HydrophobicContact CD1-CG 3.94Å; F68-L72 HydrophobicContact CE1-CD1 3.72Å; F68-L72 HydrophobicContact CE1-CD2 4Å; F68-L72 HydrophobicContact CE1-CG 3.77Å; F68-L72 HydrophobicContact CZ-CD2 4.47Å; F68-L72 HydrophobicContact CZ-CG 4.47Å; F68-L72 WeakPolarHBondContact O-CG 3.4Å; F68-L72 PolarHBondContact O-N 2.93Å; Q69-L72 PolarHBondContact O-N 3.41Å; T70-L72 PolarHBondContact O-N 2.93Å; L72-E74 VanDerWaalsContact C-N 3.29Å; L72-E74 PolarHBondContact O-N 3.09Å; L72-W75 CarbonylContact O-C 3.47Å; L72-W75 PolarHBondContact O-N 3.4Å; L72-W75 VanDerWaalsContact O-N 3.15Å; L72-L76 PolarHBondContact O-N 2.79Å; L72-L76 VanDerWaalsContact O-N 3.15Å; L72-I80 HydrophobicContact CD2-CD1 3.82Å; L72-I80 HydrophobicContact CG-CD1 4.47Å
73N94.5Very high94.6Very high84 Ų8470.8 Ų70.845%0.44939%0.389SS..Hα-helixtrans-65.9-31179.8-69.3-17.6000112.7Q69 T70 L71 W75 L76Q69-N73 PolarHBondContact NE2-OD1 3.45Å; Q69-N73 WeakPolarHBondContact O-CB 3.45Å; Q69-N73 PolarHBondContact O-N 2.91Å; Q69-N73 PolarHBondContact O-ND2 3.27Å; Q69-N73 PolarHBondContact O-OD1 3.06Å; T70-N73 WeakPolarHBondContact O-CB 3.45Å; T70-N73 PolarHBondContact O-N 3.44Å; L71-N73 VanDerWaalsContact C-N 3.3Å; L71-N73 PolarHBondContact O-N 3.35Å; N73-W75 VanDerWaalsContact C-N 3.25Å; N73-W75 PolarHBondContact O-N 2.91Å; N73-L76 WeakPolarHBondContact O-CG 3.42Å
74E94.2Very high94.6Very high132 Ų13268.4 Ų68.462%0.61738%0.377SS*.Hα-helixtrans-68.1-25.5175-70.7176.7-173.400112.8T70 L71 L72T70-E74 PolarHBondContact O-N 3.28Å; T70-E74 VanDerWaalsContact O-N 3.15Å; L71-E74 PolarHBondContact O-N 2.99Å; L72-E74 VanDerWaalsContact C-N 3.29Å; L72-E74 PolarHBondContact O-N 3.09Å
75W92.4Very high94.5Very high75 Ų7568.6 Ų68.628%0.28438%0.378SS..THydrogen-bonded Turntrans-119.822.3-173.3-63.285.1000113.5L71 L72 N73 N77 S78 I80 P81 K84L71-W75 PolarHBondContact O-N 3.27Å; L72-W75 CarbonylContact O-C 3.47Å; L72-W75 PolarHBondContact O-N 3.4Å; L72-W75 VanDerWaalsContact O-N 3.15Å; N73-W75 VanDerWaalsContact C-N 3.25Å; N73-W75 PolarHBondContact O-N 2.91Å; W75-N77 PolarHBondContact O-N 3.21Å; W75-S78 VanDerWaalsContact CE3-OG 3.28Å; W75-S78 CarbonylContact O-C 3.53Å; W75-S78 PolarHBondContact O-N 3.23Å; W75-S78 PolarHBondContact O-OG 2.83Å; W75-I80 HydrophobicContact CB-CG1 3.9Å; W75-I80 HydrophobicContact CG-CG1 4.12Å; W75-P81 HydrophobicContact CE3-CG 4.17Å; W75-P81 HydrophobicContact CH2-CG 3.33Å; W75-P81 HydrophobicContact CZ2-CG 3.71Å; W75-P81 HydrophobicContact CZ3-CG 3.59Å; W75-K84 HydrophobicContact CZ2-CG 4.29Å
76L85.2Confident94.5Very high128 Ų12871.1 Ų71.167%0.6739%0.389SS*.THydrogen-bonded Turntrans-47-30.6-174.1-74.7167.1000116.4L72 N73L72-L76 PolarHBondContact O-N 2.79Å; L72-L76 VanDerWaalsContact O-N 3.15Å; N73-L76 WeakPolarHBondContact O-CG 3.42Å
77N84.1Confident94.5Very high167 Ų16773.2 Ų73.289%0.89339%0.389SS*.THydrogen-bonded Turntrans-10914.1-176.5-61.4-43.8000113.3W75W75-N77 PolarHBondContact O-N 3.21Å
78S87.9Confident94.5Very high65 Ų6572.1 Ų72.146%0.45538%0.377SS..SBendtrans-154.5157.1-170.946.60000111.9W75W75-S78 VanDerWaalsContact CE3-OG 3.28Å; W75-S78 CarbonylContact O-C 3.53Å; W75-S78 PolarHBondContact O-N 3.23Å; W75-S78 PolarHBondContact O-OG 2.83Å
79S90.1Very high94.5Very high104 Ų10472.5 Ų72.573%0.72738%0.379SS*.PPolyproline II helixtrans-67.9136171.156.20000110.9P81S79-P81 WeakPolarHBondContact O-CD 3.27Å
80I94.8Very high94.5Very high17 Ų1775 Ų759%0.08739%0.391CS..PPolyproline II helixtrans-63.4125.5171.3-57.7170.2000108.6F68 L71 L72 W75 K84 L85F68-I80 HydrophobicContact CZ-CD1 4.23Å; L71-I80 HydrophobicContact CD1-CG2 4.26Å; L71-I80 HydrophobicContact CD2-CD1 4.32Å; L71-I80 HydrophobicContact CD2-CG2 4.18Å; L71-I80 HydrophobicContact CG-CD1 4.1Å; L71-I80 HydrophobicContact CG-CG2 4.27Å; L72-I80 HydrophobicContact CD2-CD1 3.82Å; L72-I80 HydrophobicContact CG-CD1 4.47Å; W75-I80 HydrophobicContact CB-CG1 3.9Å; W75-I80 HydrophobicContact CG-CG1 4.12Å; I80-K84 HydrophobicContact CG2-CB 3.85Å; I80-L85 HydrophobicContact CB-CD2 4.2Å; I80-L85 HydrophobicContact CB-CG 4.36Å; I80-L85 HydrophobicContact CD1-CD2 4.18Å; I80-L85 HydrophobicContact CG2-CD2 3.72Å; I80-L85 HydrophobicContact CG2-CG 3.79Å
81P95.2Very high94.6Very high42 Ų4274.6 Ų74.627%0.27340%0.395SS..PPolyproline II helixtrans-62.3143.3176-22.332.9000111.7W75 S79 T83 K84 L85W75-P81 HydrophobicContact CE3-CG 4.17Å; W75-P81 HydrophobicContact CH2-CG 3.33Å; W75-P81 HydrophobicContact CZ2-CG 3.71Å; W75-P81 HydrophobicContact CZ3-CG 3.59Å; S79-P81 WeakPolarHBondContact O-CD 3.27Å; P81-T83 PolarHBondContact O-N 3.15Å; P81-T83 VanDerWaalsContact O-N 3.14Å; P81-K84 HydrophobicContact CB-CG 4.46Å; P81-K84 HydrophobicContact CG-CG 4.4Å; P81-K84 WeakPolarHBondContact O-CB 3.32Å; P81-K84 PolarHBondContact O-N 3.25Å; P81-L85 PolarHBondContact O-N 2.9Å
82K95.8Very high94.6Very high113 Ų11374.8 Ų74.849%0.49140%0.396SS..Hα-helixtrans-51-41.1177.6-67.9-163.5-176.9-157.60112.8A43 L45 K84 L85 E86A43-K82 WeakPolarHBondContact O-CE 3.38Å; A43-K82 PolarHBondContact O-NZ 2.63Å; L45-K82 HydrophobicContact CD2-CB 4.06Å; L45-K82 HydrophobicContact CD2-CD 4.22Å; L45-K82 HydrophobicContact CD2-CG 4.22Å; K82-K84 PolarHBondContact O-N 2.97Å; K82-L85 WeakPolarHBondContact O-CB 3.22Å; K82-L85 PolarHBondContact O-N 3.09Å; K82-E86 WeakPolarHBondContact O-CG 3.16Å; K82-E86 PolarHBondContact O-N 3.44Å
83T96.8Very high94.8Very high79 Ų7973.6 Ų73.649%0.48539%0.39SS..Hα-helixtrans-59.9-32.3178.158.40000113.1P81 E86 E87P81-T83 PolarHBondContact O-N 3.15Å; P81-T83 VanDerWaalsContact O-N 3.14Å; T83-E86 WeakPolarHBondContact CA-OE2 3.3Å; T83-E87 VanDerWaalsContact O-CG 3.29Å; T83-E87 WeakPolarHBondContact O-CG 3.34Å; T83-E87 PolarHBondContact O-N 3.41Å
84K97.7Very high95Very high67 Ų6771.7 Ų71.729%0.29138%0.38SS..Hα-helixtrans-76.3-32.8176.1-67.9-49.1-170-1700112.8L71 W75 I80 P81 K82 E87 F88L71-K84 HydrophobicContact CD1-CB 4.19Å; W75-K84 HydrophobicContact CZ2-CG 4.29Å; I80-K84 HydrophobicContact CG2-CB 3.85Å; P81-K84 HydrophobicContact CB-CG 4.46Å; P81-K84 HydrophobicContact CG-CG 4.4Å; P81-K84 WeakPolarHBondContact O-CB 3.32Å; P81-K84 PolarHBondContact O-N 3.25Å; K82-K84 PolarHBondContact O-N 2.97Å; K84-E87 VanDerWaalsContact CD-OE2 3.26Å; K84-E87 WeakPolarHBondContact CD-OE2 3.27Å; K84-E87 IonicContact NZ-OE1 2.87Å; K84-E87 PolarHBondContact NZ-OE1 3.24Å; K84-E87 IonicContact NZ-OE2 3.56Å; K84-E87 PolarHBondContact NZ-OE2 3.35Å; K84-F88 WeakPolarHBondContact O-CB 3.42Å; K84-F88 PolarHBondContact O-N 3.39Å
85L97.8Very high95Very high5 Ų573.3 Ų73.33%0.02639%0.385CS..Hα-helixtrans-68.4-39.3171.4-60.6172.4000111.1H39 M40 A43 L45 F68 L71 I80 P81 K82 F88 L89H39-L85 HydrophobicContact CB-CD2 4.26Å; M40-L85 HydrophobicContact CE-CB 4.1Å; M40-L85 HydrophobicContact CE-CD2 3.64Å; M40-L85 HydrophobicContact CE-CG 4.43Å; M40-L85 HydrophobicContact SD-CB 4.14Å; M40-L85 HydrophobicContact SD-CD2 4.45Å; A43-L85 HydrophobicContact CB-CD1 3.47Å; A43-L85 VanDerWaalsContact CB-CD1 3.47Å; L45-L85 HydrophobicContact CD1-CB 3.86Å; F68-L85 HydrophobicContact CE2-CD2 3.93Å; F68-L85 HydrophobicContact CZ-CD2 4.3Å; L71-L85 HydrophobicContact CD2-CD2 4.32Å; I80-L85 HydrophobicContact CB-CD2 4.2Å; I80-L85 HydrophobicContact CB-CG 4.36Å; I80-L85 HydrophobicContact CD1-CD2 4.18Å; I80-L85 HydrophobicContact CG2-CD2 3.72Å; I80-L85 HydrophobicContact CG2-CG 3.79Å; P81-L85 PolarHBondContact O-N 2.9Å; K82-L85 WeakPolarHBondContact O-CB 3.22Å; K82-L85 PolarHBondContact O-N 3.09Å; L85-F88 WeakPolarHBondContact O-CB 3.23Å; L85-F88 PolarHBondContact O-N 3.12Å; L85-L89 WeakPolarHBondContact O-CG 3.49Å; L85-L89 PolarHBondContact O-N 2.95Å
86E97.9Very high95.1Very high98 Ų9870.6 Ų70.646%0.45838%0.377SS..Hα-helixtrans-61.9-47.7173.6-70168.7164.200111.9L45 K82 T83 F88 L89 E90L45-E86 HydrophobicContact CD1-CG 4.5Å; L45-E86 HydrophobicContact CD2-CG 4.11Å; K82-E86 WeakPolarHBondContact O-CG 3.16Å; K82-E86 PolarHBondContact O-N 3.44Å; T83-E86 WeakPolarHBondContact CA-OE2 3.3Å; E86-F88 VanDerWaalsContact C-N 3.29Å; E86-F88 PolarHBondContact O-N 3.03Å; E86-L89 PolarHBondContact O-N 3.33Å; E86-E90 PolarHBondContact O-N 3.03Å
87E98.1Very high95.4Very high101 Ų10165.6 Ų65.647%0.47236%0.357SS..Hα-helixtrans-57.4-42.3173.5-75.2171.2-153.100111.4T83 K84 E90 A91T83-E87 VanDerWaalsContact O-CG 3.29Å; T83-E87 WeakPolarHBondContact O-CG 3.34Å; T83-E87 PolarHBondContact O-N 3.41Å; K84-E87 VanDerWaalsContact CD-OE2 3.26Å; K84-E87 WeakPolarHBondContact CD-OE2 3.27Å; K84-E87 IonicContact NZ-OE1 2.87Å; K84-E87 PolarHBondContact NZ-OE1 3.24Å; K84-E87 IonicContact NZ-OE2 3.56Å; K84-E87 PolarHBondContact NZ-OE2 3.35Å; E87-E90 PolarHBondContact O-N 3.37Å; E87-A91 WeakPolarHBondContact O-CB 3.47Å; E87-A91 PolarHBondContact O-N 2.87Å
88F98.4Very high95.9Very high15 Ų1560 Ų607%0.06633%0.329CS..Hα-helixtrans-63.6-43.8176.9176.4-92.2000112.2I36 M40 V64 A67 F68 L71 K84 L85 E86 A91 N92 F93I36-F88 HydrophobicContact CD1-CE1 4.49Å; I36-F88 HydrophobicContact CD1-CZ 4.21Å; I36-F88 HydrophobicContact CG2-CE1 4.42Å; M40-F88 HydrophobicContact CE-CD1 3.51Å; M40-F88 HydrophobicContact CE-CE1 4.03Å; M40-F88 HydrophobicContact CE-CG 4.42Å; V64-F88 HydrophobicContact CG1-CE1 4.35Å; V64-F88 HydrophobicContact CG1-CZ 3.74Å; A67-F88 HydrophobicContact CB-CE2 3.97Å; F68-F88 HydrophobicContact CB-CE1 4.43Å; F68-F88 HydrophobicContact CB-CE2 3.74Å; F68-F88 HydrophobicContact CB-CZ 3.61Å; F68-F88 AromaticContact CD2-CD1 3.95Å; F68-F88 HydrophobicContact CD2-CD1 3.95Å; F68-F88 HydrophobicContact CD2-CD2 4.06Å; F68-F88 AromaticContact CD2-CE1 3.67Å; F68-F88 HydrophobicContact CD2-CE1 3.67Å; F68-F88 AromaticContact CD2-CE2 3.83Å; F68-F88 HydrophobicContact CD2-CE2 3.83Å; F68-F88 HydrophobicContact CD2-CG 4.13Å; F68-F88 AromaticContact CD2-CZ 3.63Å; F68-F88 HydrophobicContact CD2-CZ 3.63Å; F68-F88 HydrophobicContact CE2-CD1 4.4Å; F68-F88 HydrophobicContact CE2-CE1 4.4Å; F68-F88 HydrophobicContact CG-CE1 4.42Å; F68-F88 HydrophobicContact CG-CE2 4.3Å; F68-F88 HydrophobicContact CG-CZ 4.05Å; L71-F88 HydrophobicContact CD2-CB 4.06Å; L71-F88 HydrophobicContact CD2-CD2 4.35Å; L71-F88 HydrophobicContact CD2-CG 4.3Å; K84-F88 WeakPolarHBondContact O-CB 3.42Å; K84-F88 PolarHBondContact O-N 3.39Å; L85-F88 WeakPolarHBondContact O-CB 3.23Å; L85-F88 PolarHBondContact O-N 3.12Å; E86-F88 VanDerWaalsContact C-N 3.29Å; E86-F88 PolarHBondContact O-N 3.03Å; F88-A91 PolarHBondContact O-N 3.49Å; F88-N92 WeakPolarHBondContact CD2-ND2 3.47Å; F88-N92 WeakPolarHBondContact CE2-ND2 3.47Å; F88-N92 HydrophobicContact CZ-CB 4.4Å; F88-N92 WeakPolarHBondContact O-CB 3.46Å; F88-N92 PolarHBondContact O-N 3.44Å; F88-N92 PolarHBondContact O-ND2 3.05Å; F88-F93 HydrophobicContact CD1-CE2 4.45Å; F88-F93 AromaticContact CE1-CE2 3.78Å; F88-F93 HydrophobicContact CE1-CE2 3.78Å; F88-F93 HydrophobicContact CZ-CE2 4.5Å
89L97.6Very high96.2Very high9 Ų957 Ų575%0.04731%0.307CS..Hα-helixtrans-62.1-47.4175.9-75.6-179.7000111.3M40 L45 F46 F52 M55 L85 E86 A91 N92 F93M40-L89 HydrophobicContact CE-CD2 4.36Å; M40-L89 HydrophobicContact CE-CG 4.36Å; M40-L89 HydrophobicContact CG-CD2 4.31Å; M40-L89 HydrophobicContact SD-CD1 3.87Å; M40-L89 HydrophobicContact SD-CD2 3.71Å; M40-L89 HydrophobicContact SD-CG 3.66Å; L45-L89 HydrophobicContact CD1-CD1 3.57Å; F46-L89 HydrophobicContact CE2-CD1 3.85Å; F46-L89 HydrophobicContact CZ-CD1 3.97Å; F52-L89 HydrophobicContact CD2-CD2 3.76Å; F52-L89 HydrophobicContact CE2-CD2 3.6Å; M55-L89 HydrophobicContact SD-CD2 4.14Å; L85-L89 WeakPolarHBondContact O-CG 3.49Å; L85-L89 PolarHBondContact O-N 2.95Å; E86-L89 PolarHBondContact O-N 3.33Å; L89-A91 VanDerWaalsContact C-N 3.25Å; L89-A91 PolarHBondContact O-N 3.05Å; L89-N92 PolarHBondContact O-N 2.7Å; L89-F93 HydrophobicContact CD2-CD2 3.7Å; L89-F93 HydrophobicContact CD2-CE2 4.03Å; L89-F93 HydrophobicContact CD2-CG 4.12Å; L89-F93 WeakPolarHBondContact O-CB 3.39Å; L89-F93 PolarHBondContact O-N 3.38Å
90E97.4Very high96.3Very high150 Ų15053 Ų5370%0.70128%0.277SS*.Hα-helixtrans-60.3-37.6178.7-174.9172.7-165.700111.6K58 E86 E87K58-E90 PolarHBondContact NZ-O 2.82Å; E86-E90 PolarHBondContact O-N 3.03Å; E87-E90 PolarHBondContact O-N 3.37Å
91A98.1Very high96.2Very high67 Ų6755.8 Ų55.855%0.55429%0.289SS*.Hα-helixtrans-71.6-35.1177.900000113.6K58 E87 F88 L89K58-A91 WeakPolarHBondContact CD-O 3.5Å; E87-A91 WeakPolarHBondContact O-CB 3.47Å; E87-A91 PolarHBondContact O-N 2.87Å; F88-A91 PolarHBondContact O-N 3.49Å; L89-A91 VanDerWaalsContact C-N 3.25Å; L89-A91 PolarHBondContact O-N 3.05Å
92N98.4Very high95.8Very high21 Ų2160.6 Ų60.611%0.11232%0.318CS..Hα-helixtrans-114.2-13.3-165.6-66.3-82.9000115.3K58 V64 F88 L89K58-N92 WeakPolarHBondContact CB-O 3.13Å; K58-N92 PolarHBondContact N-O 3.02Å; V64-N92 HydrophobicContact CG1-CB 4.03Å; V64-N92 HydrophobicContact CG2-CB 4.25Å; F88-N92 WeakPolarHBondContact CD2-ND2 3.47Å; F88-N92 WeakPolarHBondContact CE2-ND2 3.47Å; F88-N92 HydrophobicContact CZ-CB 4.4Å; F88-N92 WeakPolarHBondContact O-CB 3.46Å; F88-N92 PolarHBondContact O-N 3.44Å; F88-N92 PolarHBondContact O-ND2 3.05Å; L89-N92 PolarHBondContact O-N 2.7Å
93F98.4Very high95.7Very high6 Ų657 Ų573%0.02630%0.302CS..EExtended strand (participates in β ladder)trans-129.3140.9-173.9-64.8-105000112.9I30 Y31 I36 F52 M55 K56 L57 K58 V64 F88 L89I30-F93 HydrophobicContact CG2-CE1 4.1Å; I30-F93 HydrophobicContact CG2-CZ 3.91Å; Y31-F93 HydrophobicContact CE1-CE1 4.35Å; I36-F93 HydrophobicContact CG2-CZ 4.41Å; F52-F93 HydrophobicContact CE2-CD1 4.34Å; F52-F93 AromaticContact CE2-CE1 3.78Å; F52-F93 HydrophobicContact CE2-CE1 3.78Å; F52-F93 HydrophobicContact CE2-CE2 4.4Å; F52-F93 AromaticContact CE2-CZ 3.84Å; F52-F93 HydrophobicContact CE2-CZ 3.84Å; F52-F93 HydrophobicContact CZ-CE1 4.1Å; F52-F93 HydrophobicContact CZ-CZ 4.06Å; M55-F93 HydrophobicContact CB-CB 4.12Å; M55-F93 HydrophobicContact CB-CD1 3.7Å; M55-F93 HydrophobicContact CB-CG 4.33Å; M55-F93 HydrophobicContact CE-CB 3.54Å; M55-F93 HydrophobicContact CE-CG 4.46Å; M55-F93 HydrophobicContact SD-CB 4.19Å; K56-F93 CarbonylContact O-C 3.09Å; K56-F93 WeakPolarHBondContact O-CA 3.41Å; L57-F93 HydrophobicContact CD2-CD1 3.7Å; L57-F93 HydrophobicContact CD2-CE1 3.18Å; L57-F93 HydrophobicContact CD2-CE2 4.25Å; L57-F93 HydrophobicContact CD2-CG 4.45Å; L57-F93 HydrophobicContact CD2-CZ 3.48Å; L57-F93 VanDerWaalsContact CD2-CZ 3.48Å; K58-F93 VanDerWaalsContact CE-C 3.49Å; K58-F93 WeakPolarHBondContact CE-O 3.49Å; K58-F93 PolarHBondContact NZ-O 3.04Å; V64-F93 HydrophobicContact CG1-CE2 3.98Å; V64-F93 HydrophobicContact CG1-CZ 4.16Å; F88-F93 HydrophobicContact CD1-CE2 4.45Å; F88-F93 AromaticContact CE1-CE2 3.78Å; F88-F93 HydrophobicContact CE1-CE2 3.78Å; F88-F93 HydrophobicContact CZ-CE2 4.5Å; L89-F93 HydrophobicContact CD2-CD2 3.7Å; L89-F93 HydrophobicContact CD2-CE2 4.03Å; L89-F93 HydrophobicContact CD2-CG 4.12Å; L89-F93 WeakPolarHBondContact O-CB 3.39Å; L89-F93 PolarHBondContact O-N 3.38Å
94D97.6Very high95.3Very high45 Ų4557.3 Ų57.324%0.24130%0.303CS..EExtended strand (participates in β ladder)trans-88.1155.5164.7-74.5-31.2000110.1M55 K56 K58 T98M55-D94 WeakPolarHBondContact CB-O 3.09Å; K56-D94 HydrophobicContact CB-CB 4.2Å; K56-D94 HydrophobicContact CD-CB 4.17Å; K56-D94 PolarHBondContact N-O 3.48Å; K56-D94 IonicContact NZ-OD2 3.94Å; K56-D94 PolarHBondContact NZ-OD2 3.34Å; K56-D94 PolarHBondContact O-N 2.97Å; K58-D94 WeakPolarHBondContact CE-OD1 3.44Å; D94-T98 HydrophobicContact CB-CG2 4.33Å
95K95.1Very high95.1Very high165 Ų16554.4 Ų54.472%0.71729%0.291SS*.PPolyproline II helixtrans-63.6152.2178.8-67-177.3179.6-179.80111.7T98K95-T98 VanDerWaalsContact O-CG2 3.27Å; K95-T98 WeakPolarHBondContact O-CG2 3.37Å; K95-T98 PolarHBondContact O-OG1 3.26Å
96P94.8Very high94.9Very high18 Ų1860.5 Ų60.512%0.11733%0.329CS..THydrogen-bonded Turntrans-57.1146.3173.1-26.137.3000112H51 D54 M55 R169H51-P96 VanDerWaalsContact O-CG 3.25Å; H51-P96 WeakPolarHBondContact O-CG 3.33Å; D54-P96 HydrophobicContact CB-CB 3.87Å; D54-P96 HydrophobicContact CB-CG 4.15Å; M55-P96 HydrophobicContact CG-CG 3.95Å; P96-R169 PolarHBondContact O-NH1 3.06Å
97G92.1Very high94.8Very high24 Ų2457.2 Ų57.225%0.24732%0.315CS..THydrogen-bonded Turntrans91.8-4.1179.600000114.7E99 F100G97-E99 WeakPolarHBondContact CA-OE2 3.39Å; G97-E99 PolarHBondContact N-OE1 3.45Å; G97-E99 PolarHBondContact N-OE2 2.63Å; G97-E99 PolarHBondContact O-N 2.87Å; G97-F100 PolarHBondContact O-N 3.06Å
98T93.2Very high94.8Very high50 Ų5055.2 Ų55.231%0.30730%0.303SS..THydrogen-bonded Turntrans-73.7-9.8175.2530000113.1D94 K95 F100 Q142D94-T98 HydrophobicContact CB-CG2 4.33Å; K95-T98 VanDerWaalsContact O-CG2 3.27Å; K95-T98 WeakPolarHBondContact O-CG2 3.37Å; K95-T98 PolarHBondContact O-OG1 3.26Å; T98-F100 VanDerWaalsContact C-N 3.31Å; T98-Q142 PolarHBondContact O-NE2 2.89Å
99E93.8Very high94.7Very high1 Ų158.3 Ų58.31%0.00532%0.317CS..THydrogen-bonded Turntrans-77.1-12.4172.664.9-85.9-162.700113.9G97 Q142 V145 Y152 Q154 R214G97-E99 WeakPolarHBondContact CA-OE2 3.39Å; G97-E99 PolarHBondContact N-OE1 3.45Å; G97-E99 PolarHBondContact N-OE2 2.63Å; G97-E99 PolarHBondContact O-N 2.87Å; E99-Q142 PolarHBondContact O-N 3.5Å; E99-V145 HydrophobicContact CB-CG2 4.04Å; E99-Y152 HydrophobicContact CB-CD1 3.83Å; E99-Y152 HydrophobicContact CB-CE1 4.07Å; E99-Q154 HydrophobicContact CB-CB 4.17Å; E99-Q154 HydrophobicContact CB-CG 4.37Å; E99-Q154 HydrophobicContact CG-CB 3.95Å; E99-Q154 HydrophobicContact CG-CG 4.05Å; E99-R214 IonicContact OE1-CZ 3.29Å; E99-R214 IonicContact OE1-NH1 3.07Å; E99-R214 PolarHBondContact OE1-NH1 3.22Å; E99-R214 IonicContact OE1-NH2 3.08Å; E99-R214 PolarHBondContact OE1-NH2 2.8Å
100F93.5Very high94.5Very high20 Ų2063.8 Ų63.89%0.08834%0.343CS..EExtended strand (participates in β ladder)trans-107.9151.2-179.5-55.7-69.8000112G97 T98 R139 K140 I141 Q142 R169G97-F100 PolarHBondContact O-N 3.06Å; T98-F100 VanDerWaalsContact C-N 3.31Å; F100-R139 HydrophobicContact CD1-CB 3.98Å; F100-R139 HydrophobicContact CE1-CB 4.41Å; F100-R139 HydrophobicContact CG-CB 4.45Å; F100-K140 CarbonylContact C-O 3.47Å; F100-K140 VanDerWaalsContact CA-O 3.31Å; F100-K140 WeakPolarHBondContact CA-O 3.39Å; F100-I141 HydrophobicContact CD1-CG1 4.07Å; F100-I141 HydrophobicContact CE1-CG1 3.86Å; F100-Q142 PolarHBondContact O-NE2 2.9Å; F100-R169 WeakPolarHBondContact CE1-O 3.42Å; F100-R169 HydrophobicContact CE2-CB 3.7Å; F100-R169 WeakPolarHBondContact CE2-O 3.43Å; F100-R169 HydrophobicContact CZ-CB 4.19Å; F100-R169 WeakPolarHBondContact CZ-O 3.39Å
101E91.4Very high94.5Very high76 Ų7663.9 Ų63.936%0.35534%0.341SS..EExtended strand (participates in β ladder)trans-112.4155.9163.861.7-177.6-157.600110.3W103 K140 Q142E101-W103 PolarHBondContact O-N 2.85Å; E101-K140 HydrophobicContact CG-CB 3.91Å; E101-K140 HydrophobicContact CG-CD 4.22Å; E101-K140 HydrophobicContact CG-CG 4.03Å; E101-K140 PolarHBondContact N-O 3Å; E101-K140 PolarHBondContact O-N 3.39Å; E101-K140 WeakPolarHBondContact OE1-CD 3.39Å; E101-K140 WeakPolarHBondContact OE1-CE 3.43Å; E101-K140 IonicContact OE1-NZ 2.69Å; E101-K140 PolarHBondContact OE1-NZ 2.86Å; E101-Q142 HydrophobicContact CB-CG 4.1Å; E101-Q142 HydrophobicContact CG-CG 4.44Å
102T87.6Confident94.4Very high142 Ų14260.8 Ų60.887%0.87132%0.315SS*.EExtended strand (participates in β ladder)trans-64.9131.6176.3-59.80000109.1
103W92.8Very high94.4Very high39 Ų3968.7 Ų68.715%0.14834%0.343CS..  trans-137.3136.3177.5172.171.9000110.2E101 P105 K140 P160 T191E101-W103 PolarHBondContact O-N 2.85Å; W103-P105 HydrophobicContact CE3-CG 4.32Å; W103-P105 HydrophobicContact CH2-CB 3.71Å; W103-P105 HydrophobicContact CH2-CG 3.55Å; W103-P105 VanDerWaalsContact CZ2-CA 3.43Å; W103-P105 HydrophobicContact CZ2-CB 3.89Å; W103-P105 HydrophobicContact CZ2-CG 4.11Å; W103-P105 HydrophobicContact CZ3-CB 4.35Å; W103-P105 HydrophobicContact CZ3-CG 3.68Å; W103-K140 HydrophobicContact CB-CB 3.59Å; W103-K140 HydrophobicContact CG-CB 4.04Å; W103-P160 HydrophobicContact CD2-CB 3.38Å; W103-P160 HydrophobicContact CD2-CG 3.81Å; W103-P160 VanDerWaalsContact CE2-CG 3.44Å; W103-P160 HydrophobicContact CE3-CB 3.52Å; W103-P160 HydrophobicContact CE3-CG 4.43Å; W103-P160 HydrophobicContact CG-CB 4.03Å; W103-P160 HydrophobicContact CG-CG 4.13Å; W103-P160 HydrophobicContact CH2-CB 3.69Å; W103-P160 HydrophobicContact CH2-CG 4.4Å; W103-P160 HydrophobicContact CZ2-CB 3.55Å; W103-P160 HydrophobicContact CZ2-CG 3.77Å; W103-P160 HydrophobicContact CZ3-CB 3.67Å; W103-T191 HydrophobicContact CH2-CG2 3.66Å; W103-T191 HydrophobicContact CZ3-CG2 4.47Å
104T88.9Confident94.3Very high84 Ų8469 Ų6952%0.51534%0.344SS..  trans-114.7127171.6-56.80000107.8T106 K135T104-T106 PolarHBondContact O-N 3.18Å; T104-K135 HydrophobicContact CG2-CG 4.47Å
105P93.1Very high94.3Very high6 Ų667.5 Ų67.54%0.03934%0.336CS..  trans-56.7127.6175.8-19.727.4000111.7W103 W108 M188W103-P105 HydrophobicContact CE3-CG 4.32Å; W103-P105 HydrophobicContact CH2-CB 3.71Å; W103-P105 HydrophobicContact CH2-CG 3.55Å; W103-P105 VanDerWaalsContact CZ2-CA 3.43Å; W103-P105 HydrophobicContact CZ2-CB 3.89Å; W103-P105 HydrophobicContact CZ2-CG 4.11Å; W103-P105 HydrophobicContact CZ3-CB 4.35Å; W103-P105 HydrophobicContact CZ3-CG 3.68Å; P105-W108 HydrophobicContact CB-CB 4.2Å; P105-M188 HydrophobicContact CB-CE 3.26Å; P105-M188 HydrophobicContact CG-CE 3.51Å
106T94.3Very high94.4Very high134 Ų13464.7 Ų64.782%0.82234%0.338SS*.THydrogen-bonded Turntrans-80.1-20.2-175.550.20000113.3T104T104-T106 PolarHBondContact O-N 3.18Å
107D96.9Very high94.6Very high29 Ų2965.8 Ų65.816%0.15535%0.352CS..THydrogen-bonded Turntrans-96.74.6178.661-18.3000112.8M188 T189 E190 T191D107-M188 WeakPolarHBondContact OD2-CA 3.27Å; D107-T189 PolarHBondContact OD2-N 3.07Å; D107-E190 HydrophobicContact CB-CB 4.32Å; D107-E190 WeakPolarHBondContact OD2-CA 3.39Å; D107-E190 WeakPolarHBondContact OD2-CB 3.35Å; D107-E190 PolarHBondContact OD2-N 2.91Å; D107-T191 PolarHBondContact OD1-OG1 3.39Å; D107-T191 PolarHBondContact OD2-N 3.09Å; D107-T191 PolarHBondContact OD2-OG1 3.46Å
108W97.1Very high94.9Very high58 Ų5864.7 Ų64.722%0.2234%0.341CS..  trans-69.2133.2172.3-173.794.9000110.5P105 E110 H131 K135 M188P105-W108 HydrophobicContact CB-CB 4.2Å; W108-E110 HydrophobicContact CH2-CB 4.04Å; W108-E110 HydrophobicContact CH2-CG 4.31Å; W108-E110 HydrophobicContact CZ3-CB 4.11Å; W108-H131 AromaticContact CD1-CE1 3.63Å; W108-H131 AromaticContact CD1-NE2 3.75Å; W108-H131 AromaticContact CD2-NE2 3.97Å; W108-H131 AromaticContact CE2-CD2 3.77Å; W108-H131 AromaticContact CE2-CE1 3.87Å; W108-H131 AromaticContact CE2-NE2 3.18Å; W108-H131 AromaticContact CZ2-CD2 3.63Å; W108-H131 AromaticContact CZ2-NE2 3.42Å; W108-H131 WeakPolarHBondContact CZ2-NE2 3.44Å; W108-H131 AromaticContact NE1-CD2 3.62Å; W108-H131 AromaticContact NE1-CE1 3.28Å; W108-H131 PolarHBondContact NE1-CE1 2.86Å; W108-H131 VanDerWaalsContact NE1-CE1 3.28Å; W108-H131 AromaticContact NE1-ND1 3.91Å; W108-H131 AromaticContact NE1-NE2 3.04Å; W108-H131 PolarHBondContact NE1-NE2 3.23Å; W108-H131 PolarHBondContact NE1-O 3.35Å; W108-H131 VanDerWaalsContact NE1-O 3.07Å; W108-K135 HydrophobicContact CD2-CD 3.79Å; W108-K135 HydrophobicContact CD2-CG 4.08Å; W108-K135 HydrophobicContact CE3-CD 4.03Å; W108-K135 HydrophobicContact CG-CD 4.24Å; W108-K135 HydrophobicContact CG-CG 4.02Å; W108-K135 HydrophobicContact CH2-CD 4.43Å; W108-K135 HydrophobicContact CZ2-CD 4.19Å; W108-K135 HydrophobicContact CZ3-CD 4.34Å; W108-M188 HydrophobicContact CB-CE 4.09Å; W108-M188 HydrophobicContact CB-SD 4.3Å; W108-M188 HydrophobicContact CG-SD 4.34Å
109Q95.7Very high95.1Very high80 Ų8065.1 Ų65.137%0.37435%0.349SS..  trans-133.7144.717762175.821.100111K111 P112 H131 E187Q109-K111 VanDerWaalsContact C-N 3.33Å; Q109-K111 PolarHBondContact O-N 3.49Å; Q109-P112 WeakPolarHBondContact O-CD 3.4Å; Q109-H131 PolarHBondContact O-NE2 2.9Å; Q109-E187 PolarHBondContact NE2-OE2 3Å
110E94.9Very high95.3Very high124 Ų12466.6 Ų66.658%0.57936%0.357SS*.SBendtrans-62.6-33.7-168.2-171175.3-158.900114.8W108 P112W108-E110 HydrophobicContact CH2-CB 4.04Å; W108-E110 HydrophobicContact CH2-CG 4.31Å; W108-E110 HydrophobicContact CZ3-CB 4.11Å; E110-P112 WeakPolarHBondContact O-CD 3.43Å
111K95.8Very high95.5Very high153 Ų15372.1 Ų72.167%0.66538%0.383SS*.SBendtrans-128.372.4-172.4-63.9-172.3179.8-177.90111.8Q109Q109-K111 VanDerWaalsContact C-N 3.33Å; Q109-K111 PolarHBondContact O-N 3.49Å
112P97.3Very high95.8Very high2 Ų274.4 Ų74.41%0.01339%0.392CS..  trans-63.3149.2175.429.2-37.3000111.6Q109 E110 F114 L115 E187Q109-P112 WeakPolarHBondContact O-CD 3.4Å; E110-P112 WeakPolarHBondContact O-CD 3.43Å; P112-F114 VanDerWaalsContact C-N 3.29Å; P112-F114 HydrophobicContact CB-CD1 3.84Å; P112-F114 HydrophobicContact CB-CE1 3.9Å; P112-F114 HydrophobicContact CG-CD1 3.77Å; P112-F114 HydrophobicContact CG-CE1 3.34Å; P112-F114 HydrophobicContact CG-CZ 4.34Å; P112-F114 PolarHBondContact O-N 2.88Å; P112-L115 HydrophobicContact CG-CD1 4Å; P112-L115 HydrophobicContact CG-CG 4.13Å; P112-L115 PolarHBondContact O-N 2.91Å; P112-E187 VanDerWaalsContact CA-OE2 3.23Å; P112-E187 WeakPolarHBondContact CA-OE2 3.39Å
113R97.4Very high96.3Very high186 Ų18667.6 Ų67.670%0.70235%0.351SS*.G310 helixtrans-57-36.2-170-77.6-178.4-116.5178.80.2114.4L115 S116 E187R113-L115 PolarHBondContact O-N 3.43Å; R113-L115 VanDerWaalsContact O-N 3.13Å; R113-S116 WeakPolarHBondContact O-CB 3.35Å; R113-S116 PolarHBondContact O-N 2.92Å; R113-S116 PolarHBondContact O-OG 2.87Å; R113-E187 IonicContact CZ-OE1 3.71Å; R113-E187 PolarHBondContact N-OE2 3.38Å; R113-E187 IonicContact NE-OE1 2.75Å; R113-E187 PolarHBondContact NE-OE1 3.13Å; R113-E187 IonicContact NE-OE2 3.73Å; R113-E187 IonicContact NH2-OE1 3.18Å; R113-E187 PolarHBondContact NH2-OE1 3.17Å
114F97.4Very high96.6Very high12 Ų1269.7 Ų69.75%0.05336%0.358CS..G310 helixtrans-58.7-29.1-175.882.7-87.5000112.9P112 S116 G117 I118 A127 L185 L545 D549P112-F114 VanDerWaalsContact C-N 3.29Å; P112-F114 HydrophobicContact CB-CD1 3.84Å; P112-F114 HydrophobicContact CB-CE1 3.9Å; P112-F114 HydrophobicContact CG-CD1 3.77Å; P112-F114 HydrophobicContact CG-CE1 3.34Å; P112-F114 HydrophobicContact CG-CZ 4.34Å; P112-F114 PolarHBondContact O-N 2.88Å; F114-S116 PolarHBondContact O-N 3.38Å; F114-S116 VanDerWaalsContact O-N 3.16Å; F114-G117 PolarHBondContact O-N 2.97Å; F114-I118 HydrophobicContact CD2-CD1 4.33Å; F114-I118 HydrophobicContact CE2-CD1 4.19Å; F114-A127 HydrophobicContact CE2-CB 4.19Å; F114-L185 HydrophobicContact CD1-CB 4.42Å; F114-L185 WeakPolarHBondContact CD1-O 3.47Å; F114-L545 HydrophobicContact CE2-CD2 3.8Å; F114-L545 HydrophobicContact CZ-CD1 4.28Å; F114-L545 HydrophobicContact CZ-CD2 3.66Å; F114-L545 HydrophobicContact CZ-CG 4.43Å; F114-D549 HydrophobicContact CB-CB 4.48Å; F114-D549 WeakPolarHBondContact CB-OD1 3.39Å
115L98.1Very high97Very high14 Ų1470 Ų707%0.07336%0.357CS..G310 helixtrans-58.2-31.8178.2-65.8176.6000112.6P112 R113 G117 I118 R124 A127 E128P112-L115 HydrophobicContact CG-CD1 4Å; P112-L115 HydrophobicContact CG-CG 4.13Å; P112-L115 PolarHBondContact O-N 2.91Å; R113-L115 PolarHBondContact O-N 3.43Å; R113-L115 VanDerWaalsContact O-N 3.13Å; L115-G117 PolarHBondContact O-N 2.93Å; L115-I118 HydrophobicContact CD2-CD1 4.27Å; L115-I118 PolarHBondContact O-N 3.39Å; L115-R124 HydrophobicContact CB-CG 4.44Å; L115-R124 WeakPolarHBondContact O-CD 3.43Å; L115-R124 WeakPolarHBondContact O-CG 3.27Å; L115-R124 PolarHBondContact O-NE 3.45Å; L115-A127 HydrophobicContact CD2-CB 3.55Å; L115-E128 HydrophobicContact CD1-CB 4.32Å
116S97.3Very high97.2Very high106 Ų10669.8 Ų69.874%0.74136%0.355SS*.G310 helixtrans-69.3-21.9178.2690000113.5R113 F114 I118R113-S116 WeakPolarHBondContact O-CB 3.35Å; R113-S116 PolarHBondContact O-N 2.92Å; R113-S116 PolarHBondContact O-OG 2.87Å; F114-S116 PolarHBondContact O-N 3.38Å; F114-S116 VanDerWaalsContact O-N 3.16Å; S116-I118 VanDerWaalsContact C-N 3.35Å
117G97.5Very high97.4Very high41 Ų4163.4 Ų63.442%0.42332%0.316SS..G310 helixtrans-79.8-13.9176.700000114.1F114 L115 G552 A553F114-G117 PolarHBondContact O-N 2.97Å; L115-G117 PolarHBondContact O-N 2.93Å; G117-G552 CarbonylContact O-C 3.53Å; G117-G552 VanDerWaalsContact O-C 3.23Å; G117-A553 PolarHBondContact O-N 3.34Å
118I98.4Very high97.5Very high1 Ų165.1 Ų65.11%0.00532%0.323CS..  trans-83.6118178.3-54.8170.6000108.3F114 L115 S116 L123 R124 A127 L548 G552F114-I118 HydrophobicContact CD2-CD1 4.33Å; F114-I118 HydrophobicContact CE2-CD1 4.19Å; L115-I118 HydrophobicContact CD2-CD1 4.27Å; L115-I118 PolarHBondContact O-N 3.39Å; S116-I118 VanDerWaalsContact C-N 3.35Å; I118-L123 HydrophobicContact CG2-CB 3.93Å; I118-R124 HydrophobicContact CB-CB 4.13Å; I118-R124 HydrophobicContact CB-CG 4.31Å; I118-R124 HydrophobicContact CG2-CB 3.99Å; I118-R124 PolarHBondContact O-NE 3.35Å; I118-R124 PolarHBondContact O-NH2 3.24Å; I118-A127 HydrophobicContact CD1-CB 3.43Å; I118-A127 VanDerWaalsContact CD1-CB 3.43Å; I118-L548 HydrophobicContact CD1-CB 3.97Å; I118-L548 HydrophobicContact CD1-CD1 4.47Å; I118-L548 HydrophobicContact CD1-CD2 4.33Å; I118-L548 HydrophobicContact CG1-CB 4.33Å; I118-L548 HydrophobicContact CG2-CD2 4.47Å; I118-G552 CarbonylContact C-O 3.59Å; I118-G552 WeakPolarHBondContact CA-O 3.33Å
119A98.2Very high97.4Very high59 Ų5966.7 Ų66.749%0.48833%0.333SS..  trans-80.4-43.8-176.700000112.9E121 R124 G552A119-E121 PolarHBondContact O-N 2.89Å; A119-R124 PolarHBondContact O-NH2 2.99Å; A119-G552 PolarHBondContact N-O 3.29Å
120D98.4Very high97.5Very high33 Ų3362.9 Ų62.918%0.17632%0.315CS..SBendtrans-69120.9178.3-176-59.2000110.8K122 L123 R124 T556 S557D120-K122 VanDerWaalsContact C-N 3.34Å; D120-K122 PolarHBondContact O-N 3.35Å; D120-K122 WeakPolarHBondContact OD1-CB 3.14Å; D120-K122 PolarHBondContact OD1-N 2.68Å; D120-L123 HydrophobicContact CB-CB 4.12Å; D120-L123 HydrophobicContact CB-CD1 4.1Å; D120-L123 HydrophobicContact CB-CG 4.05Å; D120-L123 PolarHBondContact O-N 2.96Å; D120-L123 PolarHBondContact OD1-N 3.29Å; D120-L123 VanDerWaalsContact OD1-N 3.07Å; D120-R124 WeakPolarHBondContact O-CB 2.92Å; D120-R124 PolarHBondContact O-N 3.01Å; D120-T556 WeakPolarHBondContact OD2-CA 3.47Å; D120-S557 PolarHBondContact OD1-OG 3.06Å; D120-S557 VanDerWaalsContact OD1-OG 3.1Å; D120-S557 PolarHBondContact OD2-N 2.99Å; D120-S557 PolarHBondContact OD2-OG 3.07Å
121E97.8Very high97.6Very high135 Ų13557 Ų5763%0.63129%0.287SS*.Hα-helixtrans-63.3-36.9-175.3-174.2178.8-176.100113.2A119 R124 L125A119-E121 PolarHBondContact O-N 2.89Å; E121-R124 PolarHBondContact O-N 3.33Å; E121-L125 HydrophobicContact CG-CD1 4.35Å; E121-L125 WeakPolarHBondContact O-CG 3.31Å; E121-L125 PolarHBondContact O-N 3.21Å
122K97.8Very high97.6Very high124 Ų12450.7 Ų50.754%0.53927%0.266SS..Hα-helixtrans-70.2-41.8179.6-64.3-178.3-179.7175.70110.8D120 R124 L125 W126 W504D120-K122 VanDerWaalsContact C-N 3.34Å; D120-K122 PolarHBondContact O-N 3.35Å; D120-K122 WeakPolarHBondContact OD1-CB 3.14Å; D120-K122 PolarHBondContact OD1-N 2.68Å; K122-R124 VanDerWaalsContact C-N 3.3Å; K122-L125 PolarHBondContact O-N 3.15Å; K122-W126 WeakPolarHBondContact O-CB 3.38Å; K122-W126 PolarHBondContact O-N 2.76Å; K122-W504 HydrophobicContact CB-CZ2 4.42Å; K122-W504 HydrophobicContact CD-CZ2 4.12Å
123L98.2Very high97.4Very high0 Ų052.4 Ų52.40%028%0.275CS..Hα-helixtrans-65.5-36.6174.5-63.9-173.6000111.5I118 D120 W126 A127 I500 W504 L548 L555I118-L123 HydrophobicContact CG2-CB 3.93Å; D120-L123 HydrophobicContact CB-CB 4.12Å; D120-L123 HydrophobicContact CB-CD1 4.1Å; D120-L123 HydrophobicContact CB-CG 4.05Å; D120-L123 PolarHBondContact O-N 2.96Å; D120-L123 PolarHBondContact OD1-N 3.29Å; D120-L123 VanDerWaalsContact OD1-N 3.07Å; L123-W126 HydrophobicContact CD2-CE3 4.28Å; L123-W126 PolarHBondContact O-N 3.11Å; L123-A127 WeakPolarHBondContact O-CB 3.31Å; L123-A127 PolarHBondContact O-N 2.89Å; L123-I500 HydrophobicContact CD1-CG2 4.12Å; L123-I500 HydrophobicContact CD2-CG2 4.04Å; L123-W504 HydrophobicContact CD2-CB 4.25Å; L123-W504 HydrophobicContact CD2-CD2 4.39Å; L123-W504 HydrophobicContact CD2-CG 4.04Å; L123-L548 HydrophobicContact CB-CD2 4.08Å; L123-L548 HydrophobicContact CD1-CD2 4.29Å; L123-L555 HydrophobicContact CD1-CB 3.81Å
124R98.3Very high97.3Very high82 Ų8243.6 Ų43.631%0.30924%0.241SC..Hα-helixtrans-63.8-46.5176.3-168.1-174.9-52.1113.10.2112.1L115 I118 A119 D120 E121 K122 W126 A127 E128L115-R124 HydrophobicContact CB-CG 4.44Å; L115-R124 WeakPolarHBondContact O-CD 3.43Å; L115-R124 WeakPolarHBondContact O-CG 3.27Å; L115-R124 PolarHBondContact O-NE 3.45Å; I118-R124 HydrophobicContact CB-CB 4.13Å; I118-R124 HydrophobicContact CB-CG 4.31Å; I118-R124 HydrophobicContact CG2-CB 3.99Å; I118-R124 PolarHBondContact O-NE 3.35Å; I118-R124 PolarHBondContact O-NH2 3.24Å; A119-R124 PolarHBondContact O-NH2 2.99Å; D120-R124 WeakPolarHBondContact O-CB 2.92Å; D120-R124 PolarHBondContact O-N 3.01Å; E121-R124 PolarHBondContact O-N 3.33Å; K122-R124 VanDerWaalsContact C-N 3.3Å; R124-W126 VanDerWaalsContact C-N 3.33Å; R124-W126 PolarHBondContact O-N 3.41Å; R124-A127 WeakPolarHBondContact O-CB 3.45Å; R124-A127 PolarHBondContact O-N 3.34Å; R124-E128 PolarHBondContact O-N 2.82Å
125L97.4Very high97.1Very high92 Ų9247.1 Ų47.148%0.48226%0.257SS..Hα-helixtrans-62.5-41175.8-71.4169.5000111.6E121 K122 E128 Q129E121-L125 HydrophobicContact CG-CD1 4.35Å; E121-L125 WeakPolarHBondContact O-CG 3.31Å; E121-L125 PolarHBondContact O-N 3.21Å; K122-L125 PolarHBondContact O-N 3.15Å; L125-E128 WeakPolarHBondContact O-CB 3.31Å; L125-E128 PolarHBondContact O-N 3.07Å; L125-Q129 WeakPolarHBondContact O-CG 3.22Å; L125-Q129 PolarHBondContact O-N 2.8Å; L125-Q129 VanDerWaalsContact O-N 3.12Å
126W97.7Very high96.7Very high1 Ų149.8 Ų49.80%0.00428%0.276CS..Hα-helixtrans-64.9-39175.1176.257.3000112.5K122 L123 R124 E128 Q129 I130 I500 N503 W504 Y507 M513 A544 L548K122-W126 WeakPolarHBondContact O-CB 3.38Å; K122-W126 PolarHBondContact O-N 2.76Å; L123-W126 HydrophobicContact CD2-CE3 4.28Å; L123-W126 PolarHBondContact O-N 3.11Å; R124-W126 VanDerWaalsContact C-N 3.33Å; R124-W126 PolarHBondContact O-N 3.41Å; W126-E128 VanDerWaalsContact C-N 3.31Å; W126-E128 PolarHBondContact O-N 3.43Å; W126-Q129 WeakPolarHBondContact O-CB 3.27Å; W126-Q129 PolarHBondContact O-N 2.97Å; W126-Q129 VanDerWaalsContact O-N 3.15Å; W126-I130 HydrophobicContact CD2-CD1 3.66Å; W126-I130 HydrophobicContact CD2-CG1 4.48Å; W126-I130 HydrophobicContact CE3-CD1 3.98Å; W126-I130 HydrophobicContact CG-CD1 4.32Å; W126-I130 HydrophobicContact CH2-CD1 3.7Å; W126-I130 HydrophobicContact CZ2-CD1 3.38Å; W126-I130 HydrophobicContact CZ2-CG1 4.37Å; W126-I130 HydrophobicContact CZ3-CD1 3.98Å; W126-I130 WeakPolarHBondContact O-CG1 3.49Å; W126-I130 PolarHBondContact O-N 2.87Å; W126-I500 HydrophobicContact CH2-CD1 4.38Å; W126-I500 HydrophobicContact CZ3-CD1 4.21Å; W126-I500 HydrophobicContact CZ3-CG2 3.98Å; W126-N503 HydrophobicContact CH2-CB 3.67Å; W126-N503 HydrophobicContact CZ2-CB 3.75Å; W126-W504 HydrophobicContact CD2-CB 4.12Å; W126-W504 AromaticContact CD2-CD1 3.86Å; W126-W504 HydrophobicContact CD2-CG 4.4Å; W126-W504 HydrophobicContact CE3-CB 4.1Å; W126-W504 AromaticContact CG-CD1 3.66Å; W126-W504 HydrophobicContact CH2-CB 4.3Å; W126-W504 HydrophobicContact CZ2-CB 4.28Å; W126-W504 HydrophobicContact CZ3-CB 4.21Å; W126-Y507 AromaticContact CD1-CD1 3.35Å; W126-Y507 AromaticContact CD1-CE1 3.82Å; W126-Y507 AromaticContact CD1-CG 3.74Å; W126-Y507 AromaticContact NE1-CD1 3.39Å; W126-Y507 AromaticContact NE1-CD2 3.85Å; W126-Y507 AromaticContact NE1-CG 3.23Å; W126-M513 HydrophobicContact CZ2-CE 3.96Å; W126-M513 HydrophobicContact CZ2-SD 3.83Å; W126-A544 HydrophobicContact CH2-CB 3.96Å; W126-L548 HydrophobicContact CE3-CD1 4.01Å; W126-L548 HydrophobicContact CZ3-CD1 3.79Å; W126-L548 HydrophobicContact CZ3-CG 4.46Å
127A98.2Very high96.5Very high0 Ų045.1 Ų45.10%024%0.243CC..Hα-helixtrans-62.1-38.3174.800000112.4F114 L115 I118 L123 R124 Q129 I130 H131 L545 L548F114-A127 HydrophobicContact CE2-CB 4.19Å; L115-A127 HydrophobicContact CD2-CB 3.55Å; I118-A127 HydrophobicContact CD1-CB 3.43Å; I118-A127 VanDerWaalsContact CD1-CB 3.43Å; L123-A127 WeakPolarHBondContact O-CB 3.31Å; L123-A127 PolarHBondContact O-N 2.89Å; R124-A127 WeakPolarHBondContact O-CB 3.45Å; R124-A127 PolarHBondContact O-N 3.34Å; A127-Q129 VanDerWaalsContact C-N 3.34Å; A127-I130 PolarHBondContact O-N 3.26Å; A127-H131 VanDerWaalsContact O-CB 3.31Å; A127-H131 WeakPolarHBondContact O-CB 3.49Å; A127-H131 PolarHBondContact O-N 3.03Å; A127-L545 HydrophobicContact CB-CD2 4.46Å; A127-L548 HydrophobicContact CB-CD1 3.81Å
128E97.7Very high96.3Very high65 Ų6543.3 Ų43.330%0.30423%0.225SC..Hα-helixtrans-62.3-41173.1-175.5175.5-174.700111.4L115 R124 L125 W126 H131 G132L115-E128 HydrophobicContact CD1-CB 4.32Å; R124-E128 PolarHBondContact O-N 2.82Å; L125-E128 WeakPolarHBondContact O-CB 3.31Å; L125-E128 PolarHBondContact O-N 3.07Å; W126-E128 VanDerWaalsContact C-N 3.31Å; W126-E128 PolarHBondContact O-N 3.43Å; E128-H131 PolarHBondContact O-N 3.27Å; E128-G132 PolarHBondContact O-N 3.31Å
129Q96.7Very high96Very high91 Ų9147 Ų4743%0.42524%0.238SC..Hα-helixtrans-63.5-46.5174.4-67.1171.9-36.700112L125 W126 A127 H131 G132 L133 Y507L125-Q129 WeakPolarHBondContact O-CG 3.22Å; L125-Q129 PolarHBondContact O-N 2.8Å; L125-Q129 VanDerWaalsContact O-N 3.12Å; W126-Q129 WeakPolarHBondContact O-CB 3.27Å; W126-Q129 PolarHBondContact O-N 2.97Å; W126-Q129 VanDerWaalsContact O-N 3.15Å; A127-Q129 VanDerWaalsContact C-N 3.34Å; Q129-H131 VanDerWaalsContact C-N 3.35Å; Q129-H131 PolarHBondContact O-N 2.87Å; Q129-G132 WeakPolarHBondContact O-CA 3.33Å; Q129-G132 PolarHBondContact O-N 2.75Å; Q129-G132 VanDerWaalsContact O-N 3.1Å; Q129-L133 PolarHBondContact O-N 3.03Å; Q129-Y507 HydrophobicContact CB-CE1 4.33Å
130I96.7Very high95.8Very high0 Ų047.9 Ų47.90%023%0.231CC..Hα-helixtrans-60.3-45.6176.2-66.9165.4000110.8W126 A127 G132 L133 M513 N541 A544 L545W126-I130 HydrophobicContact CD2-CD1 3.66Å; W126-I130 HydrophobicContact CD2-CG1 4.48Å; W126-I130 HydrophobicContact CE3-CD1 3.98Å; W126-I130 HydrophobicContact CG-CD1 4.32Å; W126-I130 HydrophobicContact CH2-CD1 3.7Å; W126-I130 HydrophobicContact CZ2-CD1 3.38Å; W126-I130 HydrophobicContact CZ2-CG1 4.37Å; W126-I130 HydrophobicContact CZ3-CD1 3.98Å; W126-I130 WeakPolarHBondContact O-CG1 3.49Å; W126-I130 PolarHBondContact O-N 2.87Å; A127-I130 PolarHBondContact O-N 3.26Å; I130-G132 PolarHBondContact O-N 2.99Å; I130-L133 VanDerWaalsContact O-CB 3.24Å; I130-L133 WeakPolarHBondContact O-CB 3.43Å; I130-L133 PolarHBondContact O-N 3.25Å; I130-M513 HydrophobicContact CD1-CE 4.08Å; I130-M513 HydrophobicContact CG1-CE 4.41Å; I130-N541 HydrophobicContact CG2-CB 3.67Å; I130-A544 HydrophobicContact CD1-CB 4.07Å; I130-L545 HydrophobicContact CB-CD2 4.08Å; I130-L545 HydrophobicContact CG2-CD1 4.3Å; I130-L545 HydrophobicContact CG2-CD2 3.82Å; I130-L545 HydrophobicContact CG2-CG 3.92Å
131H96.8Very high95.7Very high0 Ų046.7 Ų46.70%023%0.225CC..Hα-helixtrans-58.7-35.3175.8168.368.3000112.1W108 Q109 A127 E128 Q129 L133 W134 S186W108-H131 AromaticContact CD1-CE1 3.63Å; W108-H131 AromaticContact CD1-NE2 3.75Å; W108-H131 AromaticContact CD2-NE2 3.97Å; W108-H131 AromaticContact CE2-CD2 3.77Å; W108-H131 AromaticContact CE2-CE1 3.87Å; W108-H131 AromaticContact CE2-NE2 3.18Å; W108-H131 AromaticContact CZ2-CD2 3.63Å; W108-H131 AromaticContact CZ2-NE2 3.42Å; W108-H131 WeakPolarHBondContact CZ2-NE2 3.44Å; W108-H131 AromaticContact NE1-CD2 3.62Å; W108-H131 AromaticContact NE1-CE1 3.28Å; W108-H131 PolarHBondContact NE1-CE1 2.86Å; W108-H131 VanDerWaalsContact NE1-CE1 3.28Å; W108-H131 AromaticContact NE1-ND1 3.91Å; W108-H131 AromaticContact NE1-NE2 3.04Å; W108-H131 PolarHBondContact NE1-NE2 3.23Å; W108-H131 PolarHBondContact NE1-O 3.35Å; W108-H131 VanDerWaalsContact NE1-O 3.07Å; Q109-H131 PolarHBondContact O-NE2 2.9Å; A127-H131 VanDerWaalsContact O-CB 3.31Å; A127-H131 WeakPolarHBondContact O-CB 3.49Å; A127-H131 PolarHBondContact O-N 3.03Å; E128-H131 PolarHBondContact O-N 3.27Å; Q129-H131 VanDerWaalsContact C-N 3.35Å; Q129-H131 PolarHBondContact O-N 2.87Å; H131-L133 PolarHBondContact O-N 3.49Å; H131-W134 AromaticContact ND1-CD1 3.84Å; H131-W134 VanDerWaalsContact O-CD1 3.23Å; H131-W134 PolarHBondContact O-N 3.45Å; H131-S186 VanDerWaalsContact ND1-CB 3.29Å; H131-S186 WeakPolarHBondContact ND1-CB 3.44Å; H131-S186 PolarHBondContact ND1-OG 2.93Å; H131-S186 VanDerWaalsContact ND1-OG 3.07Å
132G95.6Very high95.6Very high21 Ų2143 Ų4322%0.21621%0.208CC..Hα-helixtrans-62.2-27.4172.700000114.3E128 Q129 I130 W134 K135E128-G132 PolarHBondContact O-N 3.31Å; Q129-G132 WeakPolarHBondContact O-CA 3.33Å; Q129-G132 PolarHBondContact O-N 2.75Å; Q129-G132 VanDerWaalsContact O-N 3.1Å; I130-G132 PolarHBondContact O-N 2.99Å; G132-W134 VanDerWaalsContact C-N 3.26Å; G132-W134 PolarHBondContact O-N 3.2Å; G132-K135 PolarHBondContact O-N 3.12Å
133L94.8Very high95.5Very high38 Ų3841.1 Ų41.120%0.19921%0.207CC..Hα-helixtrans-66.4-24.4-178.2-61.8176.4000113.1Q129 I130 H131 K135 S136 L137 M513Q129-L133 PolarHBondContact O-N 3.03Å; I130-L133 VanDerWaalsContact O-CB 3.24Å; I130-L133 WeakPolarHBondContact O-CB 3.43Å; I130-L133 PolarHBondContact O-N 3.25Å; H131-L133 PolarHBondContact O-N 3.49Å; L133-K135 PolarHBondContact O-N 3.31Å; L133-K135 VanDerWaalsContact O-N 3.16Å; L133-S136 WeakPolarHBondContact O-CB 3.4Å; L133-S136 PolarHBondContact O-N 3.34Å; L133-S136 PolarHBondContact O-OG 2.69Å; L133-L137 PolarHBondContact O-N 2.94Å; L133-M513 HydrophobicContact CD1-CG 4.09Å
134W95.4Very high95.5Very high0 Ų042.5 Ų42.50%022%0.217CC..Hα-helixtrans-55.8-33.5177.1-61.6137.3000113.2H131 G132 S136 L137 G138 V162 V179 L183 S186 M188 N541 L545H131-W134 AromaticContact ND1-CD1 3.84Å; H131-W134 VanDerWaalsContact O-CD1 3.23Å; H131-W134 PolarHBondContact O-N 3.45Å; G132-W134 VanDerWaalsContact C-N 3.26Å; G132-W134 PolarHBondContact O-N 3.2Å; W134-S136 VanDerWaalsContact C-N 3.26Å; W134-S136 PolarHBondContact O-N 3.09Å; W134-L137 HydrophobicContact CE3-CD1 4.23Å; W134-L137 HydrophobicContact CZ3-CD1 4.26Å; W134-L137 PolarHBondContact O-N 3.32Å; W134-G138 PolarHBondContact O-N 3.31Å; W134-V162 HydrophobicContact CE3-CG1 3.67Å; W134-V162 HydrophobicContact CZ3-CG1 3.86Å; W134-V179 HydrophobicContact CH2-CG1 4.44Å; W134-V179 HydrophobicContact CZ3-CG1 4.07Å; W134-L183 HydrophobicContact CB-CD2 4.37Å; W134-L183 HydrophobicContact CD2-CD2 3.99Å; W134-L183 HydrophobicContact CE3-CD2 4.41Å; W134-L183 HydrophobicContact CG-CD2 3.97Å; W134-S186 PolarHBondContact NE1-OG 2.91Å; W134-M188 HydrophobicContact CB-CE 4.16Å; W134-M188 HydrophobicContact CB-SD 4.01Å; W134-M188 HydrophobicContact CG-SD 4.09Å; W134-N541 HydrophobicContact CH2-CB 3.58Å; W134-N541 HydrophobicContact CZ2-CB 4.04Å; W134-N541 HydrophobicContact CZ3-CB 4.07Å; W134-L545 HydrophobicContact CZ2-CD1 3.9Å
135K92.7Very high95.4Very high87 Ų8738.6 Ų38.638%0.37820%0.202SC..Hα-helixtrans-64.8-30.2175.6-66-178.9-66.8-163.40113T104 W108 G132 L133T104-K135 HydrophobicContact CG2-CG 4.47Å; W108-K135 HydrophobicContact CD2-CD 3.79Å; W108-K135 HydrophobicContact CD2-CG 4.08Å; W108-K135 HydrophobicContact CE3-CD 4.03Å; W108-K135 HydrophobicContact CG-CD 4.24Å; W108-K135 HydrophobicContact CG-CG 4.02Å; W108-K135 HydrophobicContact CH2-CD 4.43Å; W108-K135 HydrophobicContact CZ2-CD 4.19Å; W108-K135 HydrophobicContact CZ3-CD 4.34Å; G132-K135 PolarHBondContact O-N 3.12Å; L133-K135 PolarHBondContact O-N 3.31Å; L133-K135 VanDerWaalsContact O-N 3.16Å
136S90.2Very high95.4Very high69 Ų6940.2 Ų40.248%0.48321%0.205SC..Hα-helixtrans-86.9-25.2-177.576.50000113.1L133 W134 R139L133-S136 WeakPolarHBondContact O-CB 3.4Å; L133-S136 PolarHBondContact O-N 3.34Å; L133-S136 PolarHBondContact O-OG 2.69Å; W134-S136 VanDerWaalsContact C-N 3.26Å; W134-S136 PolarHBondContact O-N 3.09Å; S136-R139 PolarHBondContact O-NH1 2.54Å
137L92.2Very high95.4Very high8 Ų845 Ų454%0.04223%0.23CC..Hα-helixtrans-91.4-9.3-178.9-64.5175.6000113L133 W134 V162 V163L133-L137 PolarHBondContact O-N 2.94Å; W134-L137 HydrophobicContact CE3-CD1 4.23Å; W134-L137 HydrophobicContact CZ3-CD1 4.26Å; W134-L137 PolarHBondContact O-N 3.32Å; L137-V162 HydrophobicContact CB-CG1 3.74Å; L137-V162 HydrophobicContact CD1-CG1 4.5Å; L137-V163 PolarHBondContact O-N 3.29Å; L137-V163 VanDerWaalsContact O-N 3.09Å
138G92.4Very high95.4Very high4 Ų449.5 Ų49.54%0.04125%0.251CS..EExtended strand (participates in β ladder)trans-65131.2175.400000112.8W134 V161W134-G138 PolarHBondContact O-N 3.31Å; G138-V161 CarbonylContact C-O 3.58Å; G138-V161 WeakPolarHBondContact CA-O 3.37Å
139R92.1Very high95.4Very high77 Ų7749.2 Ų49.229%0.29126%0.255SS..EExtended strand (participates in β ladder)trans-131.2143.5172.6-61.8-65.3177.4-84.5-3.8109.4F100 S136 P160 V161 V163F100-R139 HydrophobicContact CD1-CB 3.98Å; F100-R139 HydrophobicContact CE1-CB 4.41Å; F100-R139 HydrophobicContact CG-CB 4.45Å; S136-R139 PolarHBondContact O-NH1 2.54Å; R139-P160 CarbonylContact O-C 3.47Å; R139-P160 WeakPolarHBondContact O-CA 3.21Å; R139-V161 HydrophobicContact CB-CG2 4.07Å; R139-V161 PolarHBondContact N-O 2.54Å; R139-V161 PolarHBondContact O-N 3.25Å; R139-V163 HydrophobicContact CB-CG1 4.11Å; R139-V163 HydrophobicContact CG-CG1 3.63Å; R139-V163 HydrophobicContact CG-CG2 4.1Å
140K95.4Very high95.4Very high78 Ų7848.9 Ų48.934%0.33925%0.254SS..EExtended strand (participates in β ladder)trans-124.1130.5169.3-179.5174171.7-143.80108.8F100 E101 W103 P160F100-K140 CarbonylContact C-O 3.47Å; F100-K140 VanDerWaalsContact CA-O 3.31Å; F100-K140 WeakPolarHBondContact CA-O 3.39Å; E101-K140 HydrophobicContact CG-CB 3.91Å; E101-K140 HydrophobicContact CG-CD 4.22Å; E101-K140 HydrophobicContact CG-CG 4.03Å; E101-K140 PolarHBondContact N-O 3Å; E101-K140 PolarHBondContact O-N 3.39Å; E101-K140 WeakPolarHBondContact OE1-CD 3.39Å; E101-K140 WeakPolarHBondContact OE1-CE 3.43Å; E101-K140 IonicContact OE1-NZ 2.69Å; E101-K140 PolarHBondContact OE1-NZ 2.86Å; W103-K140 HydrophobicContact CB-CB 3.59Å; W103-K140 HydrophobicContact CG-CB 4.04Å; K140-P160 HydrophobicContact CB-CB 4.34Å; K140-P160 HydrophobicContact CB-CG 4.38Å; K140-P160 HydrophobicContact CD-CG 4.24Å; K140-P160 HydrophobicContact CG-CG 4.28Å
141I96.4Very high95.4Very high8 Ų849.9 Ų49.94%0.04126%0.259CS..EExtended strand (participates in β ladder)trans-77.1132.6180-59.9173.6000108.4F100 V145 Q154 I155 F156 T157F100-I141 HydrophobicContact CD1-CG1 4.07Å; F100-I141 HydrophobicContact CE1-CG1 3.86Å; I141-V145 HydrophobicContact CG2-CB 3.66Å; I141-V145 HydrophobicContact CG2-CG1 4.02Å; I141-V145 HydrophobicContact CG2-CG2 3.57Å; I141-Q154 HydrophobicContact CD1-CG 4.26Å; I141-Q154 HydrophobicContact CG2-CG 4.26Å; I141-I155 WeakPolarHBondContact CD1-O 3.4Å; I141-F156 HydrophobicContact CG2-CD2 3.98Å; I141-T157 WeakPolarHBondContact CD1-OG1 3.18Å
142Q96.1Very high95.5Very high59 Ų5950.4 Ų50.428%0.27626%0.261SS..  trans-65.5148.2178-68.8-178.123.100111.4T98 E99 F100 E101 S144 V145T98-Q142 PolarHBondContact O-NE2 2.89Å; E99-Q142 PolarHBondContact O-N 3.5Å; F100-Q142 PolarHBondContact O-NE2 2.9Å; E101-Q142 HydrophobicContact CB-CG 4.1Å; E101-Q142 HydrophobicContact CG-CG 4.44Å; Q142-S144 PolarHBondContact O-N 3.43Å; Q142-V145 WeakPolarHBondContact O-CB 3.46Å; Q142-V145 PolarHBondContact O-N 2.77Å; Q142-V145 VanDerWaalsContact O-N 3.1Å
143T95.6Very high95.6Very high83 Ų8349.5 Ų49.551%0.50925%0.251SS..Hα-helixtrans-62.4-25.4177.9-48.30000112.5V145 K146 D147T143-V145 PolarHBondContact O-N 3.1Å; T143-V145 VanDerWaalsContact O-N 3.16Å; T143-K146 WeakPolarHBondContact O-CA 3.33Å; T143-K146 VanDerWaalsContact O-CB 3.23Å; T143-K146 WeakPolarHBondContact O-CB 3.41Å; T143-K146 PolarHBondContact O-N 3.44Å; T143-D147 PolarHBondContact O-N 2.86Å
144S96.6Very high95.8Very high30 Ų3047.9 Ų47.921%0.2124%0.243CC..Hα-helixtrans-58.4-27.6174.358.10000113.7Q142 K146 D147 H148 Y152Q142-S144 PolarHBondContact O-N 3.43Å; S144-K146 VanDerWaalsContact C-N 3.29Å; S144-D147 PolarHBondContact O-N 2.79Å; S144-H148 WeakPolarHBondContact O-CA 3.46Å; S144-H148 PolarHBondContact O-N 3Å; S144-Y152 VanDerWaalsContact CB-OH 3.24Å; S144-Y152 WeakPolarHBondContact CB-OH 3.44Å; S144-Y152 WeakPolarHBondContact O-CE2 3.32Å; S144-Y152 PolarHBondContact OG-OH 2.96Å
145V97.3Very high95.9Very high0 Ų048 Ų480%024%0.244CC..Hα-helixtrans-69.4-30.6174.3-172.70000111.2E99 I141 Q142 T143 P149 Y152 Q154 F156E99-V145 HydrophobicContact CB-CG2 4.04Å; I141-V145 HydrophobicContact CG2-CB 3.66Å; I141-V145 HydrophobicContact CG2-CG1 4.02Å; I141-V145 HydrophobicContact CG2-CG2 3.57Å; Q142-V145 WeakPolarHBondContact O-CB 3.46Å; Q142-V145 PolarHBondContact O-N 2.77Å; Q142-V145 VanDerWaalsContact O-N 3.1Å; T143-V145 PolarHBondContact O-N 3.1Å; T143-V145 VanDerWaalsContact O-N 3.16Å; V145-P149 VanDerWaalsContact O-CA 3.29Å; V145-P149 WeakPolarHBondContact O-CA 3.47Å; V145-P149 WeakPolarHBondContact O-CB 3.24Å; V145-Y152 HydrophobicContact CB-CD2 4.32Å; V145-Y152 HydrophobicContact CB-CG 4.45Å; V145-Y152 HydrophobicContact CG1-CD2 4.31Å; V145-Y152 HydrophobicContact CG1-CG 4.21Å; V145-Y152 HydrophobicContact CG2-CD1 3.84Å; V145-Y152 HydrophobicContact CG2-CD2 4.21Å; V145-Y152 HydrophobicContact CG2-CE1 3.83Å; V145-Y152 HydrophobicContact CG2-CE2 4.25Å; V145-Y152 HydrophobicContact CG2-CG 4.04Å; V145-Q154 HydrophobicContact CG1-CB 4.18Å; V145-Q154 HydrophobicContact CG1-CG 4.13Å; V145-Q154 WeakPolarHBondContact CG1-O 3.35Å; V145-F156 HydrophobicContact CB-CB 4.4Å; V145-F156 HydrophobicContact CB-CD2 4.48Å; V145-F156 HydrophobicContact CG1-CB 4.01Å
146K97Very high96.1Very high125 Ų12545.4 Ų45.454%0.54323%0.232SC..Hα-helixtrans-74.5-44173.1-175-172.5172.8-174.40111.5T143 S144 F156T143-K146 WeakPolarHBondContact O-CA 3.33Å; T143-K146 VanDerWaalsContact O-CB 3.23Å; T143-K146 WeakPolarHBondContact O-CB 3.41Å; T143-K146 PolarHBondContact O-N 3.44Å; S144-K146 VanDerWaalsContact C-N 3.29Å; K146-F156 HydrophobicContact CB-CB 4.37Å; K146-F156 HydrophobicContact CB-CD1 3.89Å; K146-F156 HydrophobicContact CB-CD2 3.66Å; K146-F156 HydrophobicContact CB-CE1 4.06Å; K146-F156 HydrophobicContact CB-CE2 3.84Å; K146-F156 HydrophobicContact CB-CG 3.68Å; K146-F156 HydrophobicContact CB-CZ 4.03Å; K146-F156 HydrophobicContact CD-CD1 4.33Å; K146-F156 HydrophobicContact CD-CE1 3.82Å; K146-F156 HydrophobicContact CD-CZ 3.92Å; K146-F156 HydrophobicContact CG-CD1 3.93Å; K146-F156 HydrophobicContact CG-CE1 3.95Å; K146-F156 HydrophobicContact CG-CG 4.24Å; K146-F156 HydrophobicContact CG-CZ 4.27Å
147D97.8Very high96.4Very high101 Ų10142.2 Ų42.254%0.5421%0.21SC..Hα-helixtrans-79.5-30.6-171.7-61.5-23.5000112.4T143 S144T143-D147 PolarHBondContact O-N 2.86Å; S144-D147 PolarHBondContact O-N 2.79Å
148H97.6Very high96.7Very high95 Ų9544.8 Ų44.844%0.4423%0.227SC..  trans-133.957.7-178.6-61.9-66.2000112S144 E150 L151 Y152S144-H148 WeakPolarHBondContact O-CA 3.46Å; S144-H148 PolarHBondContact O-N 3Å; H148-E150 WeakPolarHBondContact CA-OE2 3.47Å; H148-E150 IonicContact CG-OE1 3.17Å; H148-E150 IonicContact ND1-OE1 3.13Å; H148-E150 PolarHBondContact ND1-OE1 3.44Å; H148-E150 PolarHBondContact O-N 3.07Å; H148-E150 VanDerWaalsContact O-N 3.11Å; H148-L151 HydrophobicContact CB-CD1 3.73Å; H148-L151 HydrophobicContact CB-CG 4.03Å; H148-L151 PolarHBondContact O-N 3.42Å; H148-L151 VanDerWaalsContact O-N 3.09Å; H148-Y152 HydrophobicContact CB-CE2 4.48Å; H148-Y152 WeakPolarHBondContact O-CD2 3.42Å; H148-Y152 VanDerWaalsContact O-CE2 3.29Å; H148-Y152 WeakPolarHBondContact O-CE2 3.25Å
149P97.2Very high96.9Very high60 Ų6047.7 Ų47.739%0.3924%0.239SC..G310 helixtrans-59.7-25.7-174.426.8-35.7000113.2V145 L151 Y152V145-P149 VanDerWaalsContact O-CA 3.29Å; V145-P149 WeakPolarHBondContact O-CA 3.47Å; V145-P149 WeakPolarHBondContact O-CB 3.24Å; P149-L151 PolarHBondContact O-N 3.27Å; P149-Y152 PolarHBondContact O-N 3.03Å
150E97.1Very high97.1Very high83 Ų8345.3 Ų45.339%0.38823%0.234SC..G310 helixtrans-62.8-20.6177.772.9-74.4174.900113.9P61 H148P61-E150 HydrophobicContact CG-CB 3.97Å; P61-E150 HydrophobicContact CG-CG 4.19Å; P61-E150 VanDerWaalsContact CG-O 3.28Å; P61-E150 WeakPolarHBondContact CG-O 3.3Å; H148-E150 WeakPolarHBondContact CA-OE2 3.47Å; H148-E150 IonicContact CG-OE1 3.17Å; H148-E150 IonicContact ND1-OE1 3.13Å; H148-E150 PolarHBondContact ND1-OE1 3.44Å; H148-E150 PolarHBondContact O-N 3.07Å; H148-E150 VanDerWaalsContact O-N 3.11Å
151L98.1Very high97Very high22 Ų2241.8 Ų41.812%0.11522%0.219CC..G310 helixtrans-83.9-11.9179.2-56.9-179.6000113Y31 L57 S59 H148 P149Y31-L151 PolarHBondContact OH-O 3.44Å; L57-L151 HydrophobicContact CB-CB 4.24Å; L57-L151 HydrophobicContact CB-CD2 3.97Å; L57-L151 PolarHBondContact N-O 2.93Å; S59-L151 VanDerWaalsContact C-CD2 3.49Å; S59-L151 VanDerWaalsContact O-CD2 3.24Å; S59-L151 WeakPolarHBondContact O-CD2 3.42Å; H148-L151 HydrophobicContact CB-CD1 3.73Å; H148-L151 HydrophobicContact CB-CG 4.03Å; H148-L151 PolarHBondContact O-N 3.42Å; H148-L151 VanDerWaalsContact O-N 3.09Å; P149-L151 PolarHBondContact O-N 3.27Å
152Y98Very high96.9Very high11 Ų1141.5 Ų41.54%0.04322%0.217CC..  trans-123.4147.8-169.4-55.3-95.9000111.1K56 E99 S144 V145 H148 P149 Q154K56-Y152 HydrophobicContact CB-CD1 4.08Å; K56-Y152 HydrophobicContact CB-CE1 4.2Å; K56-Y152 HydrophobicContact CD-CD1 4.16Å; K56-Y152 HydrophobicContact CD-CE1 3.42Å; K56-Y152 VanDerWaalsContact CD-CE1 3.42Å; K56-Y152 VanDerWaalsContact CE-OH 3.29Å; K56-Y152 WeakPolarHBondContact CE-OH 3.17Å; K56-Y152 HydrophobicContact CG-CD1 3.7Å; K56-Y152 HydrophobicContact CG-CE1 3.46Å; K56-Y152 VanDerWaalsContact CG-CE1 3.46Å; K56-Y152 HydrophobicContact CG-CG 4.45Å; E99-Y152 HydrophobicContact CB-CD1 3.83Å; E99-Y152 HydrophobicContact CB-CE1 4.07Å; S144-Y152 VanDerWaalsContact CB-OH 3.24Å; S144-Y152 WeakPolarHBondContact CB-OH 3.44Å; S144-Y152 WeakPolarHBondContact O-CE2 3.32Å; S144-Y152 PolarHBondContact OG-OH 2.96Å; V145-Y152 HydrophobicContact CB-CD2 4.32Å; V145-Y152 HydrophobicContact CB-CG 4.45Å; V145-Y152 HydrophobicContact CG1-CD2 4.31Å; V145-Y152 HydrophobicContact CG1-CG 4.21Å; V145-Y152 HydrophobicContact CG2-CD1 3.84Å; V145-Y152 HydrophobicContact CG2-CD2 4.21Å; V145-Y152 HydrophobicContact CG2-CE1 3.83Å; V145-Y152 HydrophobicContact CG2-CE2 4.25Å; V145-Y152 HydrophobicContact CG2-CG 4.04Å; H148-Y152 HydrophobicContact CB-CE2 4.48Å; H148-Y152 WeakPolarHBondContact O-CD2 3.42Å; H148-Y152 VanDerWaalsContact O-CE2 3.29Å; H148-Y152 WeakPolarHBondContact O-CE2 3.25Å; P149-Y152 PolarHBondContact O-N 3.03Å; Y152-Q154 VanDerWaalsContact C-N 3.34Å
153S97.8Very high96.7Very high1 Ų138.7 Ų38.71%0.00720%0.204CC..SBendtrans-79.3-22157.663.90000112.1V53 I155 R214 V215V53-S153 WeakPolarHBondContact O-CB 3.12Å; V53-S153 PolarHBondContact O-OG 3.31Å; S153-I155 PolarHBondContact O-N 3.12Å; S153-R214 CarbonylContact O-C 3.55Å; S153-R214 WeakPolarHBondContact O-CA 3.26Å; S153-R214 WeakPolarHBondContact OG-CD 3.42Å; S153-R214 PolarHBondContact OG-NH1 2.88Å; S153-V215 PolarHBondContact O-N 2.92Å
154Q97.9Very high96.3Very high4 Ų435 Ų352%0.01918%0.181CC..BIsolated β-bridgetrans-64.9126.8177.3-178.761.251.200111.2E99 I141 V145 Y152 G213E99-Q154 HydrophobicContact CB-CB 4.17Å; E99-Q154 HydrophobicContact CB-CG 4.37Å; E99-Q154 HydrophobicContact CG-CB 3.95Å; E99-Q154 HydrophobicContact CG-CG 4.05Å; I141-Q154 HydrophobicContact CD1-CG 4.26Å; I141-Q154 HydrophobicContact CG2-CG 4.26Å; V145-Q154 HydrophobicContact CG1-CB 4.18Å; V145-Q154 HydrophobicContact CG1-CG 4.13Å; V145-Q154 WeakPolarHBondContact CG1-O 3.35Å; Y152-Q154 VanDerWaalsContact C-N 3.34Å; Q154-G213 VanDerWaalsContact CD-O 3.3Å; Q154-G213 PolarHBondContact NE2-O 3.22Å
155I97.6Very high95.7Very high4 Ų433.7 Ų33.72%0.02117%0.173CC..PPolyproline II helixtrans-80.6126.6170-61.7170.5000108I141 S153 L202 Y206 G213 R214 V215 E218I141-I155 WeakPolarHBondContact CD1-O 3.4Å; S153-I155 PolarHBondContact O-N 3.12Å; I155-L202 HydrophobicContact CG2-CD2 3.78Å; I155-Y206 HydrophobicContact CD1-CE2 4.11Å; I155-Y206 HydrophobicContact CG2-CE2 4.18Å; I155-G213 PolarHBondContact N-O 2.75Å; I155-R214 VanDerWaalsContact CD1-C 3.49Å; I155-R214 WeakPolarHBondContact CD1-O 3.44Å; I155-V215 HydrophobicContact CG1-CG1 4.1Å; I155-E218 HydrophobicContact CD1-CG 4.28Å
156F97.8Very high95.1Very high32 Ų3236 Ų3614%0.1420%0.197CC..PPolyproline II helixtrans-64.2136.4174.5176.6-101.8000111.7I141 V145 K146 P158 F201I141-F156 HydrophobicContact CG2-CD2 3.98Å; V145-F156 HydrophobicContact CB-CB 4.4Å; V145-F156 HydrophobicContact CB-CD2 4.48Å; V145-F156 HydrophobicContact CG1-CB 4.01Å; K146-F156 HydrophobicContact CB-CB 4.37Å; K146-F156 HydrophobicContact CB-CD1 3.89Å; K146-F156 HydrophobicContact CB-CD2 3.66Å; K146-F156 HydrophobicContact CB-CE1 4.06Å; K146-F156 HydrophobicContact CB-CE2 3.84Å; K146-F156 HydrophobicContact CB-CG 3.68Å; K146-F156 HydrophobicContact CB-CZ 4.03Å; K146-F156 HydrophobicContact CD-CD1 4.33Å; K146-F156 HydrophobicContact CD-CE1 3.82Å; K146-F156 HydrophobicContact CD-CZ 3.92Å; K146-F156 HydrophobicContact CG-CD1 3.93Å; K146-F156 HydrophobicContact CG-CE1 3.95Å; K146-F156 HydrophobicContact CG-CG 4.24Å; K146-F156 HydrophobicContact CG-CZ 4.27Å; F156-P158 HydrophobicContact CE1-CB 4.37Å; F156-F201 VanDerWaalsContact O-CE1 3.28Å; F156-F201 WeakPolarHBondContact O-CE1 3.26Å
157T97.3Very high94.4Very high2 Ų231.6 Ų31.61%0.01218%0.177CC..  trans-131.6143.7165.662.10000110.5I141 H159 L171 N198 L202I141-T157 WeakPolarHBondContact CD1-OG1 3.18Å; T157-H159 PolarHBondContact O-N 3.42Å; T157-L171 HydrophobicContact CG2-CD2 3.61Å; T157-N198 VanDerWaalsContact CB-CG 3.49Å; T157-N198 WeakPolarHBondContact CB-OD1 3.47Å; T157-N198 HydrophobicContact CG2-CB 4.16Å; T157-L202 HydrophobicContact CG2-CD1 4.29Å; T157-L202 HydrophobicContact CG2-CD2 4.2Å; T157-L202 HydrophobicContact CG2-CG 4.24Å
158P96.9Very high93.8Very high62 Ų6227.6 Ų27.640%0.40316%0.155SC..SBendtrans-71.8-25.8-168.424.9-33.4000115.5F156 N198 F201F156-P158 HydrophobicContact CE1-CB 4.37Å; P158-N198 VanDerWaalsContact CD-OD1 3.24Å; P158-N198 WeakPolarHBondContact CD-OD1 3.37Å; P158-F201 HydrophobicContact CG-CB 4.48Å; P158-F201 HydrophobicContact CG-CD2 4.41Å; P158-F201 HydrophobicContact CG-CG 4.33Å
159H97.8Very high93.3Very high65 Ų6527.1 Ų27.130%0.30115%0.149SC..SBendtrans-108.5156.6-178.3-57.1-82.6000111.7T157 G194 Q197 N198T157-H159 PolarHBondContact O-N 3.42Å; H159-G194 WeakPolarHBondContact CB-O 3.48Å; H159-Q197 VanDerWaalsContact CD2-CB 3.43Å; H159-Q197 WeakPolarHBondContact CD2-CB 3.41Å; H159-Q197 WeakPolarHBondContact NE2-CB 3.24Å; H159-N198 WeakPolarHBondContact CA-OD1 3.17Å; H159-N198 WeakPolarHBondContact CB-OD1 3.48Å; H159-N198 PolarHBondContact N-OD1 3.38Å; H159-N198 PolarHBondContact O-ND2 3.06Å
160P96.4Very high93Very high27 Ų2724.2 Ų24.218%0.17513%0.13CC..  trans-58.9158.6168.4-20.833.1000112.6W103 R139 K140 N198W103-P160 HydrophobicContact CD2-CB 3.38Å; W103-P160 HydrophobicContact CD2-CG 3.81Å; W103-P160 VanDerWaalsContact CE2-CG 3.44Å; W103-P160 HydrophobicContact CE3-CB 3.52Å; W103-P160 HydrophobicContact CE3-CG 4.43Å; W103-P160 HydrophobicContact CG-CB 4.03Å; W103-P160 HydrophobicContact CG-CG 4.13Å; W103-P160 HydrophobicContact CH2-CB 3.69Å; W103-P160 HydrophobicContact CH2-CG 4.4Å; W103-P160 HydrophobicContact CZ2-CB 3.55Å; W103-P160 HydrophobicContact CZ2-CG 3.77Å; W103-P160 HydrophobicContact CZ3-CB 3.67Å; R139-P160 CarbonylContact O-C 3.47Å; R139-P160 WeakPolarHBondContact O-CA 3.21Å; K140-P160 HydrophobicContact CB-CB 4.34Å; K140-P160 HydrophobicContact CB-CG 4.38Å; K140-P160 HydrophobicContact CD-CG 4.24Å; K140-P160 HydrophobicContact CG-CG 4.28Å; P160-N198 PolarHBondContact O-ND2 2.82Å
161V93.8Very high92.8Very high4 Ų420.4 Ų20.42%0.02411%0.112CC..EExtended strand (participates in β ladder)trans-130.3154.2-179.5-62.40000110.6G138 R139 V163 L171 N198G138-V161 CarbonylContact C-O 3.58Å; G138-V161 WeakPolarHBondContact CA-O 3.37Å; R139-V161 HydrophobicContact CB-CG2 4.07Å; R139-V161 PolarHBondContact N-O 2.54Å; R139-V161 PolarHBondContact O-N 3.25Å; V161-V163 HydrophobicContact CG2-CG1 3.89Å; V161-L171 HydrophobicContact CB-CB 4.46Å; V161-L171 HydrophobicContact CG1-CB 4.16Å; V161-L171 HydrophobicContact CG1-CD2 4.19Å; V161-N198 WeakPolarHBondContact CG1-ND2 3.4Å
162V94.3Very high92.8Very high1 Ų119.9 Ų19.91%0.00611%0.109CC..EExtended strand (participates in β ladder)trans-103.9118.6164.7174.20000107.1W134 L137 V179 L183 T191 M195W134-V162 HydrophobicContact CE3-CG1 3.67Å; W134-V162 HydrophobicContact CZ3-CG1 3.86Å; L137-V162 HydrophobicContact CB-CG1 3.74Å; L137-V162 HydrophobicContact CD1-CG1 4.5Å; V162-V179 HydrophobicContact CB-CG1 3.65Å; V162-V179 HydrophobicContact CG1-CG1 3.55Å; V162-L183 HydrophobicContact CG2-CD1 4.12Å; V162-L183 HydrophobicContact CG2-CD2 4.21Å; V162-T191 HydrophobicContact CG2-CG2 4.23Å; V162-M195 HydrophobicContact CB-CE 4.35Å; V162-M195 HydrophobicContact CB-SD 3.9Å; V162-M195 HydrophobicContact CG2-SD 4.19Å
163V91.6Very high92.8Very high1 Ų119.4 Ų19.41%0.00611%0.107CC..  trans-90.4163-174.5-54.40000111.2L137 R139 V161 R169L137-V163 PolarHBondContact O-N 3.29Å; L137-V163 VanDerWaalsContact O-N 3.09Å; R139-V163 HydrophobicContact CB-CG1 4.11Å; R139-V163 HydrophobicContact CG-CG1 3.63Å; R139-V163 HydrophobicContact CG-CG2 4.1Å; V161-V163 HydrophobicContact CG2-CG1 3.89Å; V163-R169 WeakPolarHBondContact CG1-O 3.4Å
164P87.1Confident92.8Very high4 Ų419.8 Ų19.83%0.02611%0.109CC..  trans-60.2-49.9176.9-21.332.1000112.7F168 Y172 D175 F537 G538P164-F168 HydrophobicContact CB-CB 4Å; P164-F168 HydrophobicContact CB-CD2 4.37Å; P164-F168 HydrophobicContact CG-CB 3.96Å; P164-Y172 HydrophobicContact CG-CD2 3.77Å; P164-Y172 HydrophobicContact CG-CG 4.31Å; P164-D175 HydrophobicContact CG-CB 4.4Å; P164-F537 HydrophobicContact CB-CD1 4.02Å; P164-F537 HydrophobicContact CB-CD2 4.28Å; P164-F537 HydrophobicContact CB-CE1 3.49Å; P164-F537 VanDerWaalsContact CB-CE1 3.49Å; P164-F537 HydrophobicContact CB-CE2 3.74Å; P164-F537 HydrophobicContact CB-CG 4.44Å; P164-F537 HydrophobicContact CB-CZ 3.34Å; P164-F537 HydrophobicContact CG-CZ 4.4Å; P164-F537 CarbonylContact O-C 3.48Å; P164-F537 VanDerWaalsContact O-CA 3.22Å; P164-F537 WeakPolarHBondContact O-CA 3.29Å; P164-G538 PolarHBondContact O-N 3.11Å
165G83.4Confident92.7Very high3 Ų320 Ų203%0.03111%0.11CC..BIsolated β-bridgetrans132.8163.7-179.800000113.2R167 F168 L535G165-R167 PolarHBondContact O-N 3.38Å; G165-F168 PolarHBondContact O-N 3.32Å; G165-L535 CarbonylContact C-O 3.6Å; G165-L535 WeakPolarHBondContact CA-O 3.48Å
166G83.8Confident92.8Very high49 Ų4920 Ų2051%0.50511%0.11SC..THydrogen-bonded Turntrans64.7-124.6179.700000113.9F168 L535G166-F168 PolarHBondContact O-N 3.38Å; G166-L535 PolarHBondContact N-O 3.21Å
167R83.3Confident92.8Very high33 Ų3318.8 Ų18.813%0.12510%0.104CC..THydrogen-bonded Turntrans-69.3-19.5177.776-174.2-72.3-110.28.2113.7D48 K50 G165 R169 Q534D48-R167 IonicContact OD1-CZ 2.76Å; D48-R167 IonicContact OD1-NE 3.1Å; D48-R167 IonicContact OD1-NH2 2.67Å; D48-R167 PolarHBondContact OD1-NH2 3.25Å; D48-R167 IonicContact OD2-CZ 3.41Å; D48-R167 IonicContact OD2-NE 3.8Å; D48-R167 PolarHBondContact OD2-NE 3.09Å; D48-R167 IonicContact OD2-NH2 3.51Å; D48-R167 PolarHBondContact OD2-NH2 3.12Å; K50-R167 PolarHBondContact NZ-O 2.63Å; G165-R167 PolarHBondContact O-N 3.38Å; R167-R169 PolarHBondContact O-N 2.96Å; R167-Q534 HydrophobicContact CG-CG 4.23Å
168F85.7Confident92.9Very high16 Ų1618.7 Ų18.77%0.0710%0.104CC..BIsolated β-bridgetrans-85.194.8179.2-56.1-58000109.8P164 G165 G166 Y172 Y531 Q534 F537P164-F168 HydrophobicContact CB-CB 4Å; P164-F168 HydrophobicContact CB-CD2 4.37Å; P164-F168 HydrophobicContact CG-CB 3.96Å; G165-F168 PolarHBondContact O-N 3.32Å; G166-F168 PolarHBondContact O-N 3.38Å; F168-Y172 HydrophobicContact CB-CD2 4.18Å; F168-Y172 HydrophobicContact CB-CE2 3.69Å; F168-Y172 HydrophobicContact CD1-CD2 4.45Å; F168-Y172 HydrophobicContact CD1-CE1 4.5Å; F168-Y172 AromaticContact CD1-CE2 3.5Å; F168-Y172 HydrophobicContact CD1-CE2 3.5Å; F168-Y172 VanDerWaalsContact CD1-CE2 3.5Å; F168-Y172 AromaticContact CD1-CZ 3.53Å; F168-Y172 WeakPolarHBondContact CD1-OH 3.44Å; F168-Y172 HydrophobicContact CE1-CE2 4.44Å; F168-Y172 AromaticContact CG-CE2 3.92Å; F168-Y172 HydrophobicContact CG-CE2 3.92Å; F168-Y531 HydrophobicContact CE2-CE2 4.24Å; F168-Y531 HydrophobicContact CZ-CE1 4.44Å; F168-Y531 AromaticContact CZ-CE2 3.9Å; F168-Y531 HydrophobicContact CZ-CE2 3.9Å; F168-Y531 AromaticContact CZ-CZ 3.73Å; F168-Q534 HydrophobicContact CD2-CB 4.46Å; F168-Q534 HydrophobicContact CD2-CG 4.09Å; F168-Q534 HydrophobicContact CE2-CB 4.3Å; F168-Q534 HydrophobicContact CE2-CG 3.66Å; F168-F537 AromaticContact CD2-CE2 3.67Å; F168-F537 HydrophobicContact CD2-CE2 3.67Å; F168-F537 HydrophobicContact CD2-CZ 4.06Å; F168-F537 AromaticContact CE2-CE2 3.89Å; F168-F537 HydrophobicContact CE2-CE2 3.89Å; F168-F537 HydrophobicContact CE2-CZ 4.23Å
169R86.1Confident92.9Very high85 Ų8515.8 Ų15.832%0.3219%0.085SC..  trans-103.3-7.3-172.3-60.2176.8-178.7-1633.4112.7P96 F100 V163 R167P96-R169 PolarHBondContact O-NH1 3.06Å; F100-R169 WeakPolarHBondContact CE1-O 3.42Å; F100-R169 HydrophobicContact CE2-CB 3.7Å; F100-R169 WeakPolarHBondContact CE2-O 3.43Å; F100-R169 HydrophobicContact CZ-CB 4.19Å; F100-R169 WeakPolarHBondContact CZ-O 3.39Å; V163-R169 WeakPolarHBondContact CG1-O 3.4Å; R167-R169 PolarHBondContact O-N 2.96Å
170E91.9Very high93Very high0 Ų012.7 Ų12.70%07%0.071CC..SBendtrans-105.5167.9178.950.2-74.5125.800110.9K50 Y172 R214K50-E170 WeakPolarHBondContact CE-OE1 3.14Å; K50-E170 VanDerWaalsContact NZ-CD 3.34Å; K50-E170 IonicContact NZ-OE1 2.71Å; K50-E170 PolarHBondContact NZ-OE1 3.16Å; K50-E170 IonicContact NZ-OE2 3.98Å; K50-E170 PolarHBondContact NZ-OE2 3.13Å; K50-E170 VanDerWaalsContact NZ-OE2 3.16Å; E170-Y172 HydrophobicContact CG-CD2 4.32Å; E170-Y172 HydrophobicContact CG-CE2 3.74Å; E170-Y172 VanDerWaalsContact OE1-CE2 3.27Å; E170-Y172 WeakPolarHBondContact OE1-CE2 3.2Å; E170-Y172 PolarHBondContact OE1-OH 3.32Å; E170-R214 HydrophobicContact CB-CG 4.49Å; E170-R214 HydrophobicContact CG-CG 4.01Å; E170-R214 IonicContact OE2-CZ 2.65Å; E170-R214 IonicContact OE2-NE 3.38Å; E170-R214 PolarHBondContact OE2-NE 3.25Å; E170-R214 IonicContact OE2-NH2 3.46Å; E170-R214 PolarHBondContact OE2-NH2 2.7Å
171L92.8Very high93.1Very high2 Ų212.4 Ų12.41%0.017%0.068CC..  trans-62.1138.3164.366.196.7000109.5T157 V161 F199 L202 G212 G213T157-L171 HydrophobicContact CG2-CD2 3.61Å; V161-L171 HydrophobicContact CB-CB 4.46Å; V161-L171 HydrophobicContact CG1-CB 4.16Å; V161-L171 HydrophobicContact CG1-CD2 4.19Å; L171-F199 HydrophobicContact CD1-CD1 4.26Å; L171-F199 HydrophobicContact CD1-CE1 3.55Å; L171-F199 HydrophobicContact CD1-CZ 4.28Å; L171-L202 HydrophobicContact CD1-CD1 3.76Å; L171-L202 HydrophobicContact CD2-CD1 4.14Å; L171-G212 CarbonylContact O-C 3.57Å; L171-G212 WeakPolarHBondContact O-CA 3.32Å; L171-G213 PolarHBondContact O-N 3.38Å
172Y97Very high93.3Very high12 Ų1212.2 Ų12.25%0.0477%0.066CC..BIsolated β-bridgetrans-118.2140.6167-81.8-92.9000108.8P164 F168 E170 D175 S176 N211 Y217P164-Y172 HydrophobicContact CG-CD2 3.77Å; P164-Y172 HydrophobicContact CG-CG 4.31Å; F168-Y172 HydrophobicContact CB-CD2 4.18Å; F168-Y172 HydrophobicContact CB-CE2 3.69Å; F168-Y172 HydrophobicContact CD1-CD2 4.45Å; F168-Y172 HydrophobicContact CD1-CE1 4.5Å; F168-Y172 AromaticContact CD1-CE2 3.5Å; F168-Y172 HydrophobicContact CD1-CE2 3.5Å; F168-Y172 VanDerWaalsContact CD1-CE2 3.5Å; F168-Y172 AromaticContact CD1-CZ 3.53Å; F168-Y172 WeakPolarHBondContact CD1-OH 3.44Å; F168-Y172 HydrophobicContact CE1-CE2 4.44Å; F168-Y172 AromaticContact CG-CE2 3.92Å; F168-Y172 HydrophobicContact CG-CE2 3.92Å; E170-Y172 HydrophobicContact CG-CD2 4.32Å; E170-Y172 HydrophobicContact CG-CE2 3.74Å; E170-Y172 VanDerWaalsContact OE1-CE2 3.27Å; E170-Y172 WeakPolarHBondContact OE1-CE2 3.2Å; E170-Y172 PolarHBondContact OE1-OH 3.32Å; Y172-D175 WeakPolarHBondContact CB-OD2 3.39Å; Y172-S176 WeakPolarHBondContact O-CB 3.46Å; Y172-S176 PolarHBondContact O-N 2.96Å; Y172-S176 PolarHBondContact O-OG 3.48Å; Y172-N211 WeakPolarHBondContact CD1-OD1 3.04Å; Y172-N211 WeakPolarHBondContact CE1-OD1 3.28Å; Y172-Y217 HydrophobicContact CE1-CE2 4.28Å; Y172-Y217 PolarHBondContact OH-OH 2.93Å
173Y98.4Very high93.5Very high0 Ų012.1 Ų12.10%07%0.066CC..THydrogen-bonded Turntrans-66.5-67-165.4-179.5-162000112.7D175 S176 F199 V209 N211 Q222 P224 F225 L226 M229 E253Y173-D175 PolarHBondContact O-N 2.9Å; Y173-S176 WeakPolarHBondContact O-CB 3.43Å; Y173-S176 PolarHBondContact O-N 3.47Å; Y173-F199 HydrophobicContact CD2-CD1 4.18Å; Y173-F199 HydrophobicContact CD2-CE1 4.01Å; Y173-F199 HydrophobicContact CD2-CZ 4.45Å; Y173-V209 HydrophobicContact CD1-CB 3.62Å; Y173-V209 HydrophobicContact CD1-CG1 3.72Å; Y173-V209 HydrophobicContact CD1-CG2 4.47Å; Y173-V209 HydrophobicContact CD2-CB 3.97Å; Y173-V209 HydrophobicContact CD2-CG1 3.57Å; Y173-V209 HydrophobicContact CD2-CG2 4.2Å; Y173-V209 HydrophobicContact CE1-CB 3.62Å; Y173-V209 HydrophobicContact CE1-CG1 4.18Å; Y173-V209 HydrophobicContact CE1-CG2 4.1Å; Y173-V209 HydrophobicContact CE2-CB 4.04Å; Y173-V209 HydrophobicContact CE2-CG1 4.11Å; Y173-V209 HydrophobicContact CE2-CG2 3.88Å; Y173-V209 HydrophobicContact CG-CB 3.8Å; Y173-V209 HydrophobicContact CG-CG1 3.38Å; Y173-N211 PolarHBondContact N-O 3.15Å; Y173-N211 VanDerWaalsContact N-O 3.08Å; Y173-Q222 HydrophobicContact CD1-CB 3.9Å; Y173-Q222 HydrophobicContact CG-CB 4.28Å; Y173-P224 HydrophobicContact CE1-CB 4.4Å; Y173-P224 VanDerWaalsContact OH-CA 3.31Å; Y173-P224 WeakPolarHBondContact OH-CA 3.23Å; Y173-F225 PolarHBondContact OH-N 3.36Å; Y173-L226 HydrophobicContact CE2-CB 3.81Å; Y173-L226 WeakPolarHBondContact OH-CB 3.33Å; Y173-L226 PolarHBondContact OH-N 3.11Å; Y173-M229 HydrophobicContact CD2-CE 3.98Å; Y173-M229 HydrophobicContact CE2-CE 3.99Å; Y173-M229 WeakPolarHBondContact O-CE 3.39Å; Y173-E253 WeakPolarHBondContact CE1-OE1 3.41Å; Y173-E253 PolarHBondContact OH-OE1 3.15Å; Y173-E253 PolarHBondContact OH-OE2 3.43Å
174W97.9Very high93.9Very high10 Ų1013.4 Ų13.44%0.0387%0.072CC..THydrogen-bonded Turntrans-72-33.7-171.775.6-34.2000112.8S176 Y177 W178 Q222 P223 F225 G318 W319 W463 W539W174-S176 PolarHBondContact O-N 3.38Å; W174-S176 VanDerWaalsContact O-N 3.15Å; W174-Y177 WeakPolarHBondContact O-CB 3.24Å; W174-Y177 PolarHBondContact O-N 2.9Å; W174-W178 HydrophobicContact CD2-CZ3 4.39Å; W174-W178 HydrophobicContact CE3-CH2 4.19Å; W174-W178 HydrophobicContact CE3-CZ3 4.3Å; W174-W178 WeakPolarHBondContact O-CZ3 3.18Å; W174-Q222 VanDerWaalsContact N-OE1 3.14Å; W174-P223 HydrophobicContact CB-CB 4.17Å; W174-P223 HydrophobicContact CB-CG 4.46Å; W174-P223 HydrophobicContact CD2-CB 4.41Å; W174-P223 HydrophobicContact CD2-CG 3.96Å; W174-P223 HydrophobicContact CE3-CB 3.95Å; W174-P223 HydrophobicContact CE3-CG 3.6Å; W174-P223 HydrophobicContact CG-CG 4.34Å; W174-P223 HydrophobicContact CZ3-CG 4.12Å; W174-F225 HydrophobicContact CB-CD2 3.78Å; W174-F225 HydrophobicContact CB-CE2 4.23Å; W174-F225 HydrophobicContact CE3-CE2 4.19Å; W174-G318 WeakPolarHBondContact CZ2-O 3.41Å; W174-W319 AromaticContact CH2-CD1 3.77Å; W174-W319 AromaticContact CH2-NE1 3.76Å; W174-W463 AromaticContact CH2-CH2 3.44Å; W174-W463 HydrophobicContact CH2-CH2 3.44Å; W174-W463 VanDerWaalsContact CH2-CH2 3.44Å; W174-W463 HydrophobicContact CH2-CZ2 4.02Å; W174-W463 HydrophobicContact CH2-CZ3 4.01Å; W174-W463 AromaticContact CZ2-CH2 3.54Å; W174-W463 HydrophobicContact CZ2-CH2 3.54Å; W174-W463 AromaticContact CZ2-CZ2 3.72Å; W174-W463 HydrophobicContact CZ2-CZ2 3.72Å; W174-W539 AromaticContact CE2-CZ3 3.87Å; W174-W539 HydrophobicContact CZ2-CH2 4.34Å; W174-W539 AromaticContact CZ2-CZ3 3.75Å; W174-W539 HydrophobicContact CZ2-CZ3 3.75Å; W174-W539 AromaticContact NE1-CZ3 3.92Å
175D96.4Very high94.4Very high9 Ų915 Ų155%0.0488%0.081CC..Hα-helixtrans-49.8-41.6173-62.9-110.8000111.4P164 Y172 Y173 Y177 W178 V179P164-D175 HydrophobicContact CG-CB 4.4Å; Y172-D175 WeakPolarHBondContact CB-OD2 3.39Å; Y173-D175 PolarHBondContact O-N 2.9Å; D175-Y177 PolarHBondContact O-N 3.36Å; D175-Y177 VanDerWaalsContact O-N 3.11Å; D175-W178 PolarHBondContact O-N 2.88Å; D175-V179 PolarHBondContact O-N 3.3Å
176S98.3Very high95.1Very high2 Ų214.9 Ų14.91%0.0148%0.079CC..Hα-helixtrans-64.7-18.2-175.1-66.30000112.9Y172 Y173 W174 V179 I180 F199Y172-S176 WeakPolarHBondContact O-CB 3.46Å; Y172-S176 PolarHBondContact O-N 2.96Å; Y172-S176 PolarHBondContact O-OG 3.48Å; Y173-S176 WeakPolarHBondContact O-CB 3.43Å; Y173-S176 PolarHBondContact O-N 3.47Å; W174-S176 PolarHBondContact O-N 3.38Å; W174-S176 VanDerWaalsContact O-N 3.15Å; S176-V179 PolarHBondContact O-N 3.06Å; S176-I180 VanDerWaalsContact O-CB 3.22Å; S176-I180 WeakPolarHBondContact O-CB 3.49Å; S176-I180 WeakPolarHBondContact O-CD1 3.24Å; S176-I180 WeakPolarHBondContact O-CG1 3.14Å; S176-I180 PolarHBondContact O-N 2.88Å; S176-F199 VanDerWaalsContact CB-CE2 3.48Å; S176-F199 VanDerWaalsContact CB-CZ 3.41Å; S176-F199 WeakPolarHBondContact OG-CZ 3.27Å
177Y98.7Very high95.8Very high7 Ų714.6 Ų14.63%0.0277%0.065CC..Hα-helixtrans-62-51.3175.3171.9-113.4000110.6W174 D175 V179 I180 N181 F225 L228 M229W174-Y177 WeakPolarHBondContact O-CB 3.24Å; W174-Y177 PolarHBondContact O-N 2.9Å; D175-Y177 PolarHBondContact O-N 3.36Å; D175-Y177 VanDerWaalsContact O-N 3.11Å; Y177-V179 VanDerWaalsContact C-N 3.33Å; Y177-V179 PolarHBondContact O-N 3.42Å; Y177-I180 PolarHBondContact O-N 3.5Å; Y177-N181 WeakPolarHBondContact CD2-ND2 3.44Å; Y177-N181 WeakPolarHBondContact CE2-ND2 3.43Å; Y177-N181 PolarHBondContact O-N 2.99Å; Y177-N181 VanDerWaalsContact O-N 3.08Å; Y177-N181 PolarHBondContact O-ND2 3.15Å; Y177-F225 AromaticContact CD1-CD1 3.56Å; Y177-F225 HydrophobicContact CD1-CD1 3.56Å; Y177-F225 AromaticContact CD1-CE1 3.72Å; Y177-F225 HydrophobicContact CD1-CE1 3.72Å; Y177-F225 HydrophobicContact CD2-CD1 4.03Å; Y177-F225 HydrophobicContact CE1-CD1 4.12Å; Y177-F225 HydrophobicContact CE1-CE1 4.06Å; Y177-F225 HydrophobicContact CG-CB 4.36Å; Y177-F225 AromaticContact CG-CD1 3.5Å; Y177-F225 HydrophobicContact CG-CD1 3.5Å; Y177-F225 HydrophobicContact CG-CE1 4.16Å; Y177-F225 HydrophobicContact CG-CG 4.26Å; Y177-L228 HydrophobicContact CD2-CB 3.94Å; Y177-L228 HydrophobicContact CE2-CB 3.57Å; Y177-L228 HydrophobicContact CE2-CD2 4.24Å; Y177-M229 HydrophobicContact CD2-CG 4.07Å
178W98.6Very high96.5Very high0 Ų013 Ų130%06%0.059CC..Hα-helixtrans-69.2-34.8179.2-64.5-82.5000111.8W174 D175 N181 G182 F225 P471 H474 M475 W539 G542 V543W174-W178 HydrophobicContact CD2-CZ3 4.39Å; W174-W178 HydrophobicContact CE3-CH2 4.19Å; W174-W178 HydrophobicContact CE3-CZ3 4.3Å; W174-W178 WeakPolarHBondContact O-CZ3 3.18Å; D175-W178 PolarHBondContact O-N 2.88Å; W178-N181 PolarHBondContact O-N 3.09Å; W178-G182 PolarHBondContact O-N 2.93Å; W178-F225 HydrophobicContact CH2-CE1 4.16Å; W178-F225 HydrophobicContact CH2-CE2 4.31Å; W178-F225 AromaticContact CH2-CZ 3.86Å; W178-F225 HydrophobicContact CH2-CZ 3.86Å; W178-F225 HydrophobicContact CZ2-CE1 4.3Å; W178-F225 HydrophobicContact CZ2-CZ 4.27Å; W178-P471 HydrophobicContact CD2-CB 4.15Å; W178-P471 HydrophobicContact CE3-CB 4.06Å; W178-P471 HydrophobicContact CH2-CB 3.15Å; W178-P471 HydrophobicContact CH2-CG 4.4Å; W178-P471 HydrophobicContact CZ2-CB 3.21Å; W178-P471 HydrophobicContact CZ3-CB 3.58Å; W178-H474 AromaticContact CD1-CG 3.99Å; W178-H474 AromaticContact CD1-ND1 3.95Å; W178-H474 AromaticContact NE1-CG 3.59Å; W178-H474 AromaticContact NE1-ND1 3.35Å; W178-H474 PolarHBondContact NE1-ND1 3.29Å; W178-M475 HydrophobicContact CZ2-CG 4.33Å; W178-M475 HydrophobicContact CZ2-SD 4.31Å; W178-W539 HydrophobicContact CB-CB 3.97Å; W178-W539 HydrophobicContact CD2-CB 4.5Å; W178-W539 HydrophobicContact CE3-CB 4.22Å; W178-W539 HydrophobicContact CE3-CE3 4.4Å; W178-W539 HydrophobicContact CG-CB 4.42Å; W178-W539 HydrophobicContact CZ3-CE3 4.41Å; W178-G542 VanDerWaalsContact O-CA 3.27Å; W178-G542 WeakPolarHBondContact O-CA 3.29Å; W178-V543 HydrophobicContact CB-CG2 4.19Å; W178-V543 HydrophobicContact CG-CG2 3.74Å
179V98.4Very high97Very high2 Ų214 Ų141%0.0127%0.066CC..Hα-helixtrans-60.3-51.2173.1175.40000110.8W134 V162 D175 S176 Y177 N181 G182 L183 M195 G538W134-V179 HydrophobicContact CH2-CG1 4.44Å; W134-V179 HydrophobicContact CZ3-CG1 4.07Å; V162-V179 HydrophobicContact CB-CG1 3.65Å; V162-V179 HydrophobicContact CG1-CG1 3.55Å; D175-V179 PolarHBondContact O-N 3.3Å; S176-V179 PolarHBondContact O-N 3.06Å; Y177-V179 VanDerWaalsContact C-N 3.33Å; Y177-V179 PolarHBondContact O-N 3.42Å; V179-N181 VanDerWaalsContact C-N 3.33Å; V179-N181 PolarHBondContact O-N 2.84Å; V179-G182 PolarHBondContact O-N 3.41Å; V179-G182 VanDerWaalsContact O-N 3.12Å; V179-L183 HydrophobicContact CG1-CD1 3.81Å; V179-L183 HydrophobicContact CG1-CG 4.22Å; V179-L183 VanDerWaalsContact O-CG 3.25Å; V179-L183 WeakPolarHBondContact O-CG 3.4Å; V179-L183 PolarHBondContact O-N 3.35Å; V179-M195 HydrophobicContact CG1-CE 4.02Å; V179-M195 HydrophobicContact CG1-SD 4.17Å; V179-G538 VanDerWaalsContact CG2-C 3.46Å
180I98.8Very high97.6Very high0 Ų015.9 Ų15.90%08%0.079CC..Hα-helixtrans-58-43.8179.2-76.3163.2000111.3S176 Y177 L183 I184 A192 M195 I196 F199 M229S176-I180 VanDerWaalsContact O-CB 3.22Å; S176-I180 WeakPolarHBondContact O-CB 3.49Å; S176-I180 WeakPolarHBondContact O-CD1 3.24Å; S176-I180 WeakPolarHBondContact O-CG1 3.14Å; S176-I180 PolarHBondContact O-N 2.88Å; Y177-I180 PolarHBondContact O-N 3.5Å; I180-L183 PolarHBondContact O-N 3.25Å; I180-I184 HydrophobicContact CG2-CD1 3.89Å; I180-I184 VanDerWaalsContact O-CG1 3.29Å; I180-I184 WeakPolarHBondContact O-CG1 3.31Å; I180-I184 PolarHBondContact O-N 3.1Å; I180-A192 HydrophobicContact CG2-CB 4.26Å; I180-M195 HydrophobicContact CD1-CB 4.25Å; I180-M195 HydrophobicContact CG1-CB 4.24Å; I180-M195 HydrophobicContact CG1-CE 4.49Å; I180-M195 HydrophobicContact CG1-SD 4.47Å; I180-I196 HydrophobicContact CD1-CG1 3.74Å; I180-I196 HydrophobicContact CG2-CD1 4.19Å; I180-F199 HydrophobicContact CD1-CE2 4.26Å; I180-M229 HydrophobicContact CD1-CB 4.02Å; I180-M229 HydrophobicContact CD1-CE 4.48Å; I180-M229 HydrophobicContact CD1-CG 3.72Å; I180-M229 HydrophobicContact CD1-SD 3.58Å; I180-M229 VanDerWaalsContact CD1-SD 3.58Å
181N98.8Very high97.9Very high20 Ų2016.3 Ų16.311%0.1078%0.081CC..Hα-helixtrans-65-41.7176.3-73.7-72.9000112.1Y177 W178 V179 L183 I184 L185 S232 Q546Y177-N181 WeakPolarHBondContact CD2-ND2 3.44Å; Y177-N181 WeakPolarHBondContact CE2-ND2 3.43Å; Y177-N181 PolarHBondContact O-N 2.99Å; Y177-N181 VanDerWaalsContact O-N 3.08Å; Y177-N181 PolarHBondContact O-ND2 3.15Å; W178-N181 PolarHBondContact O-N 3.09Å; V179-N181 VanDerWaalsContact C-N 3.33Å; V179-N181 PolarHBondContact O-N 2.84Å; N181-L183 VanDerWaalsContact C-N 3.33Å; N181-L183 PolarHBondContact O-N 2.79Å; N181-I184 PolarHBondContact O-N 3.48Å; N181-L185 WeakPolarHBondContact O-CG 3.46Å; N181-L185 PolarHBondContact O-N 2.95Å; N181-S232 VanDerWaalsContact OD1-CB 3.26Å; N181-S232 WeakPolarHBondContact OD1-CB 3.48Å; N181-S232 PolarHBondContact OD1-OG 2.64Å; N181-Q546 VanDerWaalsContact CB-CD 3.43Å; N181-Q546 HydrophobicContact CB-CG 4.08Å; N181-Q546 VanDerWaalsContact CB-OE1 3.22Å
182G98.4Very high98.2Very high0 Ų016.2 Ų16.20%08%0.081CC..Hα-helixtrans-62.5-37174.200000113.5W178 V179 S186W178-G182 PolarHBondContact O-N 2.93Å; V179-G182 PolarHBondContact O-N 3.41Å; V179-G182 VanDerWaalsContact O-N 3.12Å; G182-S186 VanDerWaalsContact O-CB 3.27Å; G182-S186 WeakPolarHBondContact O-CB 3.21Å; G182-S186 PolarHBondContact O-N 2.73Å; G182-S186 PolarHBondContact O-OG 2.92Å
183L98.6Very high98.2Very high0 Ų019 Ų190%09%0.092CC..Hα-helixtrans-67.4-44174.8-70.2169.9000111.7W134 V162 V179 I180 N181 L185 S186 E187 M188 T191 A192 M195W134-L183 HydrophobicContact CB-CD2 4.37Å; W134-L183 HydrophobicContact CD2-CD2 3.99Å; W134-L183 HydrophobicContact CE3-CD2 4.41Å; W134-L183 HydrophobicContact CG-CD2 3.97Å; V162-L183 HydrophobicContact CG2-CD1 4.12Å; V162-L183 HydrophobicContact CG2-CD2 4.21Å; V179-L183 HydrophobicContact CG1-CD1 3.81Å; V179-L183 HydrophobicContact CG1-CG 4.22Å; V179-L183 VanDerWaalsContact O-CG 3.25Å; V179-L183 WeakPolarHBondContact O-CG 3.4Å; V179-L183 PolarHBondContact O-N 3.35Å; I180-L183 PolarHBondContact O-N 3.25Å; N181-L183 VanDerWaalsContact C-N 3.33Å; N181-L183 PolarHBondContact O-N 2.79Å; L183-L185 PolarHBondContact O-N 3.35Å; L183-S186 CarbonylContact O-C 3.25Å; L183-S186 WeakPolarHBondContact O-CA 3.29Å; L183-S186 WeakPolarHBondContact O-CB 3.43Å; L183-S186 PolarHBondContact O-N 2.64Å; L183-S186 VanDerWaalsContact O-N 3.11Å; L183-E187 PolarHBondContact O-N 3.26Å; L183-M188 HydrophobicContact CB-CB 4.22Å; L183-M188 HydrophobicContact CD2-CB 4.11Å; L183-M188 HydrophobicContact CD2-CE 3.66Å; L183-M188 HydrophobicContact CD2-SD 3.61Å; L183-M188 WeakPolarHBondContact O-CA 3.37Å; L183-M188 WeakPolarHBondContact O-CB 3.46Å; L183-M188 PolarHBondContact O-N 3.04Å; L183-T191 HydrophobicContact CD1-CG2 3.87Å; L183-T191 HydrophobicContact CD2-CG2 4.23Å; L183-A192 HydrophobicContact CB-CB 4.24Å; L183-M195 HydrophobicContact CD1-SD 3.61Å
184I98.7Very high98.2Very high27 Ų2719.2 Ų19.214%0.1389%0.094CC..Hα-helixtrans-59.8-46.7175.9-72.1166.8000110.7I180 N181 S186 E187 A192 A236I180-I184 HydrophobicContact CG2-CD1 3.89Å; I180-I184 VanDerWaalsContact O-CG1 3.29Å; I180-I184 WeakPolarHBondContact O-CG1 3.31Å; I180-I184 PolarHBondContact O-N 3.1Å; N181-I184 PolarHBondContact O-N 3.48Å; I184-S186 PolarHBondContact O-N 2.87Å; I184-E187 PolarHBondContact O-N 3.25Å; I184-A192 HydrophobicContact CD1-CB 4.45Å; I184-A192 HydrophobicContact CG1-CB 3.85Å; I184-A236 HydrophobicContact CG2-CB 3.55Å
185L97.9Very high98.3Very high38 Ų3818.8 Ų18.820%0.1999%0.092CC..Hα-helixtrans-61.1-35.4174.8-71.9174.3000112.2F114 N181 L183 E187 L545 Q546 D549F114-L185 HydrophobicContact CD1-CB 4.42Å; F114-L185 WeakPolarHBondContact CD1-O 3.47Å; N181-L185 WeakPolarHBondContact O-CG 3.46Å; N181-L185 PolarHBondContact O-N 2.95Å; L183-L185 PolarHBondContact O-N 3.35Å; L185-E187 PolarHBondContact O-N 3.35Å; L185-L545 HydrophobicContact CD1-CB 4.48Å; L185-Q546 HydrophobicContact CD1-CB 4.3Å; L185-Q546 HydrophobicContact CD1-CG 3.72Å; L185-D549 HydrophobicContact CD1-CB 3.98Å; L185-D549 HydrophobicContact CD2-CB 4.04Å
186S98.3Very high98.4Very high0 Ų018.4 Ų18.40%09%0.09CC..THydrogen-bonded Turntrans-73.76.2174.7-63.10000114H131 W134 G182 L183 I184 M188H131-S186 VanDerWaalsContact ND1-CB 3.29Å; H131-S186 WeakPolarHBondContact ND1-CB 3.44Å; H131-S186 PolarHBondContact ND1-OG 2.93Å; H131-S186 VanDerWaalsContact ND1-OG 3.07Å; W134-S186 PolarHBondContact NE1-OG 2.91Å; G182-S186 VanDerWaalsContact O-CB 3.27Å; G182-S186 WeakPolarHBondContact O-CB 3.21Å; G182-S186 PolarHBondContact O-N 2.73Å; G182-S186 PolarHBondContact O-OG 2.92Å; L183-S186 CarbonylContact O-C 3.25Å; L183-S186 WeakPolarHBondContact O-CA 3.29Å; L183-S186 WeakPolarHBondContact O-CB 3.43Å; L183-S186 PolarHBondContact O-N 2.64Å; L183-S186 VanDerWaalsContact O-N 3.11Å; I184-S186 PolarHBondContact O-N 2.87Å; S186-M188 PolarHBondContact O-N 3.03Å
187E98.1Very high98.4Very high43 Ų4320.3 Ų20.320%0.20110%0.099CC..THydrogen-bonded Turntrans59.523.1-175.2-65178.196.600113.8Q109 P112 R113 L183 I184 L185 T189Q109-E187 PolarHBondContact NE2-OE2 3Å; P112-E187 VanDerWaalsContact CA-OE2 3.23Å; P112-E187 WeakPolarHBondContact CA-OE2 3.39Å; R113-E187 IonicContact CZ-OE1 3.71Å; R113-E187 PolarHBondContact N-OE2 3.38Å; R113-E187 IonicContact NE-OE1 2.75Å; R113-E187 PolarHBondContact NE-OE1 3.13Å; R113-E187 IonicContact NE-OE2 3.73Å; R113-E187 IonicContact NH2-OE1 3.18Å; R113-E187 PolarHBondContact NH2-OE1 3.17Å; L183-E187 PolarHBondContact O-N 3.26Å; I184-E187 PolarHBondContact O-N 3.25Å; L185-E187 PolarHBondContact O-N 3.35Å; E187-T189 VanDerWaalsContact C-N 3.3Å; E187-T189 PolarHBondContact O-N 3.33Å
188M98.1Very high98.4Very high0 Ų020 Ų200%010%0.098CC..  trans-9554.6177.2-58.3173.466.100111P105 D107 W108 W134 L183 S186 E190 T191 A192P105-M188 HydrophobicContact CB-CE 3.26Å; P105-M188 HydrophobicContact CG-CE 3.51Å; D107-M188 WeakPolarHBondContact OD2-CA 3.27Å; W108-M188 HydrophobicContact CB-CE 4.09Å; W108-M188 HydrophobicContact CB-SD 4.3Å; W108-M188 HydrophobicContact CG-SD 4.34Å; W134-M188 HydrophobicContact CB-CE 4.16Å; W134-M188 HydrophobicContact CB-SD 4.01Å; W134-M188 HydrophobicContact CG-SD 4.09Å; L183-M188 HydrophobicContact CB-CB 4.22Å; L183-M188 HydrophobicContact CD2-CB 4.11Å; L183-M188 HydrophobicContact CD2-CE 3.66Å; L183-M188 HydrophobicContact CD2-SD 3.61Å; L183-M188 WeakPolarHBondContact O-CA 3.37Å; L183-M188 WeakPolarHBondContact O-CB 3.46Å; L183-M188 PolarHBondContact O-N 3.04Å; S186-M188 PolarHBondContact O-N 3.03Å; M188-E190 PolarHBondContact O-N 2.91Å; M188-T191 HydrophobicContact CE-CG2 4.47Å; M188-T191 PolarHBondContact O-N 3.02Å; M188-A192 PolarHBondContact O-N 3.46Å
189T97.8Very high98.4Very high37 Ų3720.1 Ų20.123%0.22710%0.098CC..Hα-helixtrans-68.7-30.7-172.3-53.90000113.2D107 E187 Y193 Y233 T237D107-T189 PolarHBondContact OD2-N 3.07Å; E187-T189 VanDerWaalsContact C-N 3.3Å; E187-T189 PolarHBondContact O-N 3.33Å; T189-Y193 WeakPolarHBondContact O-CB 3.31Å; T189-Y193 PolarHBondContact O-N 2.94Å; T189-Y233 HydrophobicContact CG2-CD2 4.12Å; T189-Y233 HydrophobicContact CG2-CE2 3.55Å; T189-T237 HydrophobicContact CG2-CG2 3.43Å; T189-T237 VanDerWaalsContact CG2-CG2 3.43Å
190E97.9Very high98.5Very high124 Ų12420.2 Ų20.258%0.57910%0.099SC*.Hα-helixtrans-72.5-39.3177.2-64.6-60.513800111D107 M188 Y193 G194D107-E190 HydrophobicContact CB-CB 4.32Å; D107-E190 WeakPolarHBondContact OD2-CA 3.39Å; D107-E190 WeakPolarHBondContact OD2-CB 3.35Å; D107-E190 PolarHBondContact OD2-N 2.91Å; M188-E190 PolarHBondContact O-N 2.91Å; E190-Y193 WeakPolarHBondContact O-CB 3.47Å; E190-Y193 PolarHBondContact O-N 3.36Å; E190-G194 PolarHBondContact O-N 2.72Å
191T98.2Very high98.5Very high10 Ų1023.1 Ų23.16%0.06111%0.112CC..Hα-helixtrans-62.7-46.6172.8-66.50000111W103 D107 V162 L183 M188 Y193 G194 M195W103-T191 HydrophobicContact CH2-CG2 3.66Å; W103-T191 HydrophobicContact CZ3-CG2 4.47Å; D107-T191 PolarHBondContact OD1-OG1 3.39Å; D107-T191 PolarHBondContact OD2-N 3.09Å; D107-T191 PolarHBondContact OD2-OG1 3.46Å; V162-T191 HydrophobicContact CG2-CG2 4.23Å; L183-T191 HydrophobicContact CD1-CG2 3.87Å; L183-T191 HydrophobicContact CD2-CG2 4.23Å; M188-T191 HydrophobicContact CE-CG2 4.47Å; M188-T191 PolarHBondContact O-N 3.02Å; T191-Y193 VanDerWaalsContact C-N 3.35Å; T191-Y193 PolarHBondContact O-N 2.98Å; T191-G194 PolarHBondContact O-N 2.84Å; T191-M195 PolarHBondContact O-N 3.15Å
192A98.4Very high98.4Very high0 Ų022.2 Ų22.20%011%0.107CC..Hα-helixtrans-59.7-44.2175.700000111.9I180 L183 I184 M188 G194 M195 I196I180-A192 HydrophobicContact CG2-CB 4.26Å; L183-A192 HydrophobicContact CB-CB 4.24Å; I184-A192 HydrophobicContact CD1-CB 4.45Å; I184-A192 HydrophobicContact CG1-CB 3.85Å; M188-A192 PolarHBondContact O-N 3.46Å; A192-G194 PolarHBondContact O-N 2.67Å; A192-M195 PolarHBondContact O-N 3.24Å; A192-I196 WeakPolarHBondContact O-CG1 3.44Å; A192-I196 PolarHBondContact O-N 2.84Å; A192-I196 VanDerWaalsContact O-N 3.08Å
193Y98.6Very high98.5Very high70 Ų7022.2 Ų22.228%0.27511%0.107SC..Hα-helixtrans-56.8-49.7174.3175.9-106.7000111.8T189 E190 T191 M195 I196 Q197 Y233 F242T189-Y193 WeakPolarHBondContact O-CB 3.31Å; T189-Y193 PolarHBondContact O-N 2.94Å; E190-Y193 WeakPolarHBondContact O-CB 3.47Å; E190-Y193 PolarHBondContact O-N 3.36Å; T191-Y193 VanDerWaalsContact C-N 3.35Å; T191-Y193 PolarHBondContact O-N 2.98Å; Y193-M195 VanDerWaalsContact C-N 3.35Å; Y193-M195 PolarHBondContact O-N 2.93Å; Y193-I196 PolarHBondContact O-N 3.44Å; Y193-I196 VanDerWaalsContact O-N 3.15Å; Y193-Q197 HydrophobicContact CD1-CG 4.14Å; Y193-Q197 HydrophobicContact CD2-CG 4.38Å; Y193-Q197 HydrophobicContact CE1-CG 3.72Å; Y193-Q197 HydrophobicContact CE2-CG 4.02Å; Y193-Q197 VanDerWaalsContact CE2-NE2 3.27Å; Y193-Q197 HydrophobicContact CG-CG 4.44Å; Y193-Q197 WeakPolarHBondContact O-CG 3.22Å; Y193-Q197 PolarHBondContact O-N 3.09Å; Y193-Q197 PolarHBondContact OH-NE2 2.85Å; Y193-Y233 AromaticContact CD2-CE1 3.77Å; Y193-Y233 HydrophobicContact CD2-CE1 3.77Å; Y193-Y233 HydrophobicContact CD2-CE2 4.04Å; Y193-Y233 AromaticContact CD2-CZ 3.45Å; Y193-Y233 VanDerWaalsContact CD2-CZ 3.45Å; Y193-Y233 VanDerWaalsContact CD2-OH 3.31Å; Y193-Y233 WeakPolarHBondContact CD2-OH 3.17Å; Y193-Y233 HydrophobicContact CE2-CE1 4.41Å; Y193-Y233 HydrophobicContact CG-CE2 4.26Å; Y193-F242 HydrophobicContact CD2-CD2 4.08Å; Y193-F242 HydrophobicContact CD2-CE2 4.42Å; Y193-F242 HydrophobicContact CE2-CB 4.47Å; Y193-F242 AromaticContact CE2-CD2 3.59Å; Y193-F242 HydrophobicContact CE2-CD2 3.59Å; Y193-F242 HydrophobicContact CE2-CE2 4.22Å; Y193-F242 HydrophobicContact CE2-CG 4.28Å
194G98.4Very high98.5Very high4 Ų428.6 Ų28.64%0.04114%0.137CC..Hα-helixtrans-58.9-42.717900000113H159 E190 T191 A192 I196 Q197 N198H159-G194 WeakPolarHBondContact CB-O 3.48Å; E190-G194 PolarHBondContact O-N 2.72Å; T191-G194 PolarHBondContact O-N 2.84Å; A192-G194 PolarHBondContact O-N 2.67Å; G194-I196 PolarHBondContact O-N 3.13Å; G194-Q197 PolarHBondContact O-N 2.74Å; G194-N198 PolarHBondContact O-N 3.21Å
195M98.6Very high98.4Very high2 Ų233.2 Ų33.21%0.0115%0.152CC..Hα-helixtrans-61.4-42.4174.8-72.8-1756800112.1V162 V179 I180 L183 T191 A192 Y193 N198 F199V162-M195 HydrophobicContact CB-CE 4.35Å; V162-M195 HydrophobicContact CB-SD 3.9Å; V162-M195 HydrophobicContact CG2-SD 4.19Å; V179-M195 HydrophobicContact CG1-CE 4.02Å; V179-M195 HydrophobicContact CG1-SD 4.17Å; I180-M195 HydrophobicContact CD1-CB 4.25Å; I180-M195 HydrophobicContact CG1-CB 4.24Å; I180-M195 HydrophobicContact CG1-CE 4.49Å; I180-M195 HydrophobicContact CG1-SD 4.47Å; L183-M195 HydrophobicContact CD1-SD 3.61Å; T191-M195 PolarHBondContact O-N 3.15Å; A192-M195 PolarHBondContact O-N 3.24Å; Y193-M195 VanDerWaalsContact C-N 3.35Å; Y193-M195 PolarHBondContact O-N 2.93Å; M195-N198 WeakPolarHBondContact O-CB 3.19Å; M195-N198 PolarHBondContact O-N 3.17Å; M195-F199 WeakPolarHBondContact O-CD2 3.44Å; M195-F199 PolarHBondContact O-N 2.78Å
196I98.8Very high98.4Very high0 Ų033.7 Ų33.70%015%0.152CC..Hα-helixtrans-65.4-40.7176.5-62.1164.8000111.1I180 A192 Y193 G194 N198 F199 L200 L226 M229 Y233 F242I180-I196 HydrophobicContact CD1-CG1 3.74Å; I180-I196 HydrophobicContact CG2-CD1 4.19Å; A192-I196 WeakPolarHBondContact O-CG1 3.44Å; A192-I196 PolarHBondContact O-N 2.84Å; A192-I196 VanDerWaalsContact O-N 3.08Å; Y193-I196 PolarHBondContact O-N 3.44Å; Y193-I196 VanDerWaalsContact O-N 3.15Å; G194-I196 PolarHBondContact O-N 3.13Å; I196-N198 VanDerWaalsContact C-N 3.28Å; I196-N198 PolarHBondContact O-N 3.03Å; I196-F199 PolarHBondContact O-N 3.49Å; I196-F199 VanDerWaalsContact O-N 3.13Å; I196-L200 HydrophobicContact CG2-CD1 4.23Å; I196-L200 HydrophobicContact CG2-CG 4.39Å; I196-L200 WeakPolarHBondContact O-CG 3.36Å; I196-L200 PolarHBondContact O-N 2.8Å; I196-L226 HydrophobicContact CG2-CD1 4.17Å; I196-M229 HydrophobicContact CD1-CB 4.28Å; I196-M229 WeakPolarHBondContact CD1-O 3.25Å; I196-M229 HydrophobicContact CG1-CB 4.07Å; I196-Y233 HydrophobicContact CD1-CD2 4.42Å; I196-Y233 HydrophobicContact CD1-CG 4.05Å; I196-F242 HydrophobicContact CG2-CE2 3.98Å; I196-F242 HydrophobicContact CG2-CZ 3.69Å
197Q98.8Very high98.4Very high43 Ų4334.8 Ų34.820%0.20116%0.163CC..Hα-helixtrans-60.2-36.9174.5-69.4-58.3-44.400112.3H159 Y193 G194 F199 L200 F201H159-Q197 VanDerWaalsContact CD2-CB 3.43Å; H159-Q197 WeakPolarHBondContact CD2-CB 3.41Å; H159-Q197 WeakPolarHBondContact NE2-CB 3.24Å; Y193-Q197 HydrophobicContact CD1-CG 4.14Å; Y193-Q197 HydrophobicContact CD2-CG 4.38Å; Y193-Q197 HydrophobicContact CE1-CG 3.72Å; Y193-Q197 HydrophobicContact CE2-CG 4.02Å; Y193-Q197 VanDerWaalsContact CE2-NE2 3.27Å; Y193-Q197 HydrophobicContact CG-CG 4.44Å; Y193-Q197 WeakPolarHBondContact O-CG 3.22Å; Y193-Q197 PolarHBondContact O-N 3.09Å; Y193-Q197 PolarHBondContact OH-NE2 2.85Å; G194-Q197 PolarHBondContact O-N 2.74Å; Q197-F199 VanDerWaalsContact C-N 3.34Å; Q197-F199 PolarHBondContact O-N 3.39Å; Q197-L200 PolarHBondContact O-N 3.49Å; Q197-F201 WeakPolarHBondContact O-CB 3.11Å; Q197-F201 PolarHBondContact O-N 2.86Å
198N98.8Very high98.4Very high1 Ų133.5 Ų33.51%0.00516%0.157CC..Hα-helixtrans-61.4-41.9173.6-70.8-24.7000112.2T157 P158 H159 P160 V161 G194 M195 I196 F201 L202T157-N198 VanDerWaalsContact CB-CG 3.49Å; T157-N198 WeakPolarHBondContact CB-OD1 3.47Å; T157-N198 HydrophobicContact CG2-CB 4.16Å; P158-N198 VanDerWaalsContact CD-OD1 3.24Å; P158-N198 WeakPolarHBondContact CD-OD1 3.37Å; H159-N198 WeakPolarHBondContact CA-OD1 3.17Å; H159-N198 WeakPolarHBondContact CB-OD1 3.48Å; H159-N198 PolarHBondContact N-OD1 3.38Å; H159-N198 PolarHBondContact O-ND2 3.06Å; P160-N198 PolarHBondContact O-ND2 2.82Å; V161-N198 WeakPolarHBondContact CG1-ND2 3.4Å; G194-N198 PolarHBondContact O-N 3.21Å; M195-N198 WeakPolarHBondContact O-CB 3.19Å; M195-N198 PolarHBondContact O-N 3.17Å; I196-N198 VanDerWaalsContact C-N 3.28Å; I196-N198 PolarHBondContact O-N 3.03Å; N198-F201 WeakPolarHBondContact O-CB 3.29Å; N198-F201 PolarHBondContact O-N 3.17Å; N198-L202 VanDerWaalsContact O-CG 3.31Å; N198-L202 WeakPolarHBondContact O-CG 3.47Å; N198-L202 PolarHBondContact O-N 2.78Å
199F98.9Very high98.5Very high2 Ų233.5 Ų33.51%0.00916%0.157CC..Hα-helixtrans-67.1-41.8176.4-68.9-56.5000112.6L171 Y173 S176 I180 M195 I196 Q197 F201 L202 V203 V209 L226 M229L171-F199 HydrophobicContact CD1-CD1 4.26Å; L171-F199 HydrophobicContact CD1-CE1 3.55Å; L171-F199 HydrophobicContact CD1-CZ 4.28Å; Y173-F199 HydrophobicContact CD2-CD1 4.18Å; Y173-F199 HydrophobicContact CD2-CE1 4.01Å; Y173-F199 HydrophobicContact CD2-CZ 4.45Å; S176-F199 VanDerWaalsContact CB-CE2 3.48Å; S176-F199 VanDerWaalsContact CB-CZ 3.41Å; S176-F199 WeakPolarHBondContact OG-CZ 3.27Å; I180-F199 HydrophobicContact CD1-CE2 4.26Å; M195-F199 WeakPolarHBondContact O-CD2 3.44Å; M195-F199 PolarHBondContact O-N 2.78Å; I196-F199 PolarHBondContact O-N 3.49Å; I196-F199 VanDerWaalsContact O-N 3.13Å; Q197-F199 VanDerWaalsContact C-N 3.34Å; Q197-F199 PolarHBondContact O-N 3.39Å; F199-F201 VanDerWaalsContact C-N 3.31Å; F199-F201 PolarHBondContact O-N 3.23Å; F199-L202 HydrophobicContact CD1-CD1 4.34Å; F199-L202 PolarHBondContact O-N 2.97Å; F199-L202 VanDerWaalsContact O-N 3.15Å; F199-V203 WeakPolarHBondContact O-CG2 3.38Å; F199-V203 PolarHBondContact O-N 2.84Å; F199-V209 HydrophobicContact CB-CG2 4.15Å; F199-V209 HydrophobicContact CD1-CB 4.47Å; F199-V209 HydrophobicContact CD1-CG1 3.43Å; F199-V209 VanDerWaalsContact CD1-CG1 3.43Å; F199-V209 HydrophobicContact CD1-CG2 4.16Å; F199-V209 HydrophobicContact CE1-CG1 3.81Å; F199-V209 HydrophobicContact CG-CG1 4.5Å; F199-L226 HydrophobicContact CB-CD1 3.45Å; F199-L226 VanDerWaalsContact CB-CD1 3.45Å; F199-L226 HydrophobicContact CB-CD2 4.05Å; F199-L226 HydrophobicContact CB-CG 4.35Å; F199-L226 HydrophobicContact CD2-CD1 4.26Å; F199-L226 HydrophobicContact CG-CD1 4.16Å; F199-M229 HydrophobicContact CD2-CE 4.47Å; F199-M229 HydrophobicContact CD2-SD 3.75Å; F199-M229 HydrophobicContact CE2-CE 4.09Å; F199-M229 HydrophobicContact CE2-SD 3.84Å
200L98.9Very high98.5Very high4 Ų431.7 Ų31.72%0.02115%0.146CC..Hα-helixtrans-59.7-44174.2-64.6171.9000111.1I196 Q197 L202 V203 E204 L226 F242 A246 I249 L250I196-L200 HydrophobicContact CG2-CD1 4.23Å; I196-L200 HydrophobicContact CG2-CG 4.39Å; I196-L200 WeakPolarHBondContact O-CG 3.36Å; I196-L200 PolarHBondContact O-N 2.8Å; Q197-L200 PolarHBondContact O-N 3.49Å; L200-L202 VanDerWaalsContact C-N 3.31Å; L200-L202 PolarHBondContact O-N 3.14Å; L200-V203 PolarHBondContact O-N 2.86Å; L200-E204 WeakPolarHBondContact O-CG 3.46Å; L200-E204 PolarHBondContact O-N 3.34Å; L200-L226 HydrophobicContact CD2-CD2 4.04Å; L200-F242 HydrophobicContact CD1-CE2 3.99Å; L200-A246 HydrophobicContact CD1-CB 3.78Å; L200-A246 HydrophobicContact CD2-CB 4.04Å; L200-I249 HydrophobicContact CB-CD1 4.03Å; L200-I249 HydrophobicContact CB-CG2 4.16Å; L200-I249 HydrophobicContact CD2-CB 3.86Å; L200-I249 HydrophobicContact CD2-CD1 4.31Å; L200-I249 HydrophobicContact CD2-CG2 3.71Å; L200-L250 HydrophobicContact CD2-CD2 4.08Å
201F98.7Very high98.5Very high61 Ų6126.1 Ų26.127%0.26812%0.12SC..Hα-helixtrans-57.9-41173.9171.6-92.1000112.6F156 P158 Q197 N198 F199 E204 R205F156-F201 VanDerWaalsContact O-CE1 3.28Å; F156-F201 WeakPolarHBondContact O-CE1 3.26Å; P158-F201 HydrophobicContact CG-CB 4.48Å; P158-F201 HydrophobicContact CG-CD2 4.41Å; P158-F201 HydrophobicContact CG-CG 4.33Å; Q197-F201 WeakPolarHBondContact O-CB 3.11Å; Q197-F201 PolarHBondContact O-N 2.86Å; N198-F201 WeakPolarHBondContact O-CB 3.29Å; N198-F201 PolarHBondContact O-N 3.17Å; F199-F201 VanDerWaalsContact C-N 3.31Å; F199-F201 PolarHBondContact O-N 3.23Å; F201-E204 PolarHBondContact O-N 2.94Å; F201-R205 WeakPolarHBondContact O-CB 3.43Å; F201-R205 PolarHBondContact O-N 2.83Å; F201-R205 VanDerWaalsContact O-N 3.11Å
202L98.7Very high98.4Very high1 Ų125.6 Ų25.61%0.00512%0.117CC..Hα-helixtrans-67.2-40.2176.7-69.6170.1000111.9I155 T157 L171 N198 F199 L200 R205 Y206 V209I155-L202 HydrophobicContact CG2-CD2 3.78Å; T157-L202 HydrophobicContact CG2-CD1 4.29Å; T157-L202 HydrophobicContact CG2-CD2 4.2Å; T157-L202 HydrophobicContact CG2-CG 4.24Å; L171-L202 HydrophobicContact CD1-CD1 3.76Å; L171-L202 HydrophobicContact CD2-CD1 4.14Å; N198-L202 VanDerWaalsContact O-CG 3.31Å; N198-L202 WeakPolarHBondContact O-CG 3.47Å; N198-L202 PolarHBondContact O-N 2.78Å; F199-L202 HydrophobicContact CD1-CD1 4.34Å; F199-L202 PolarHBondContact O-N 2.97Å; F199-L202 VanDerWaalsContact O-N 3.15Å; L200-L202 VanDerWaalsContact C-N 3.31Å; L200-L202 PolarHBondContact O-N 3.14Å; L202-R205 PolarHBondContact O-N 2.85Å; L202-Y206 HydrophobicContact CD2-CD2 4.19Å; L202-Y206 HydrophobicContact CD2-CE2 3.98Å; L202-Y206 WeakPolarHBondContact O-CB 3.4Å; L202-Y206 WeakPolarHBondContact O-CD2 3.19Å; L202-Y206 PolarHBondContact O-N 2.86Å; L202-V209 HydrophobicContact CD1-CG1 4.48Å
203V98.8Very high98.3Very high0 Ų025.6 Ų25.60%012%0.117CC..Hα-helixtrans-64.4-40.3174.8176.50000111.4F199 L200 R205 G207 V209 L226 I249 T252 E253F199-V203 WeakPolarHBondContact O-CG2 3.38Å; F199-V203 PolarHBondContact O-N 2.84Å; L200-V203 PolarHBondContact O-N 2.86Å; V203-R205 VanDerWaalsContact C-N 3.25Å; V203-R205 PolarHBondContact O-N 2.85Å; V203-G207 WeakPolarHBondContact O-CA 3.11Å; V203-G207 PolarHBondContact O-N 3.15Å; V203-V209 HydrophobicContact CG2-CG2 3.49Å; V203-V209 VanDerWaalsContact CG2-CG2 3.49Å; V203-L226 HydrophobicContact CG2-CD2 3.84Å; V203-I249 HydrophobicContact CB-CG2 3.56Å; V203-I249 HydrophobicContact CG1-CG2 3.53Å; V203-I249 WeakPolarHBondContact CG1-O 3.44Å; V203-I249 HydrophobicContact CG2-CG2 4.42Å; V203-T252 HydrophobicContact CG1-CG2 4.04Å; V203-E253 HydrophobicContact CG1-CB 3.98Å; V203-E253 HydrophobicContact CG2-CB 4.08Å
204E98.4Very high98.3Very high134 Ų13422.4 Ų22.463%0.62610%0.104SC*.Hα-helixtrans-61.9-35.9175.1-72-177.7135.900112.2L200 F201 I249L200-E204 WeakPolarHBondContact O-CG 3.46Å; L200-E204 PolarHBondContact O-N 3.34Å; F201-E204 PolarHBondContact O-N 2.94Å; E204-I249 HydrophobicContact CG-CD1 3.86Å; E204-I249 HydrophobicContact CG-CG1 4.06Å; E204-I249 HydrophobicContact CG-CG2 4.23Å; E204-I249 WeakPolarHBondContact OE1-CD1 3.22Å
205R97.4Very high98.3Very high124 Ų12423.2 Ų23.247%0.46811%0.108SC..Hα-helixtrans-78.9-42.5-179.2-178171.6173.2168.1-1.8113.5F201 L202 V203F201-R205 WeakPolarHBondContact O-CB 3.43Å; F201-R205 PolarHBondContact O-N 2.83Å; F201-R205 VanDerWaalsContact O-N 3.11Å; L202-R205 PolarHBondContact O-N 2.85Å; V203-R205 VanDerWaalsContact C-N 3.25Å; V203-R205 PolarHBondContact O-N 2.85Å
206Y97.7Very high98.2Very high47 Ų4723.1 Ų23.118%0.18411%0.108CC..Hα-helixtrans-113.4-10.8-169-64.9-73.4000113.9I155 L202 F208 P210 E218I155-Y206 HydrophobicContact CD1-CE2 4.11Å; I155-Y206 HydrophobicContact CG2-CE2 4.18Å; L202-Y206 HydrophobicContact CD2-CD2 4.19Å; L202-Y206 HydrophobicContact CD2-CE2 3.98Å; L202-Y206 WeakPolarHBondContact O-CB 3.4Å; L202-Y206 WeakPolarHBondContact O-CD2 3.19Å; L202-Y206 PolarHBondContact O-N 2.86Å; Y206-F208 WeakPolarHBondContact O-CD1 3.27Å; Y206-F208 WeakPolarHBondContact O-CE1 3.27Å; Y206-F208 PolarHBondContact O-N 3.01Å; Y206-P210 HydrophobicContact CD2-CG 3.85Å; Y206-P210 HydrophobicContact CE2-CG 4.28Å; Y206-P210 HydrophobicContact CG-CG 4.22Å; Y206-E218 HydrophobicContact CD1-CG 4.38Å; Y206-E218 HydrophobicContact CE1-CB 4.43Å; Y206-E218 HydrophobicContact CE1-CG 3.62Å; Y206-E218 WeakPolarHBondContact CE1-OE1 3.45Å; Y206-E218 PolarHBondContact OH-OE1 3Å
207G98.4Very high98.2Very high23 Ų2323.6 Ų23.624%0.23711%0.11CC..SBendtrans82.4-7.1-172.900000114.2V203 F256V203-G207 WeakPolarHBondContact O-CA 3.11Å; V203-G207 PolarHBondContact O-N 3.15Å; G207-F256 WeakPolarHBondContact O-CB 3.42Å
208F98.6Very high98Very high16 Ų1623.3 Ų23.37%0.0711%0.109CC..SBendtrans-157.3169.4178.964.8-82.5000109.6Y206 P210 E218 E253 F256Y206-F208 WeakPolarHBondContact O-CD1 3.27Å; Y206-F208 WeakPolarHBondContact O-CE1 3.27Å; Y206-F208 PolarHBondContact O-N 3.01Å; F208-P210 HydrophobicContact CE2-CB 4.49Å; F208-P210 HydrophobicContact CE2-CG 4.45Å; F208-P210 WeakPolarHBondContact O-CD 3.45Å; F208-E218 WeakPolarHBondContact CZ-O 3.11Å; F208-E253 HydrophobicContact CB-CG 4.46Å; F208-F256 HydrophobicContact CB-CB 4.15Å; F208-F256 HydrophobicContact CB-CD1 3.47Å; F208-F256 VanDerWaalsContact CB-CD1 3.47Å; F208-F256 HydrophobicContact CB-CD2 4.03Å; F208-F256 HydrophobicContact CB-CE1 3.75Å; F208-F256 HydrophobicContact CB-CE2 4.27Å; F208-F256 HydrophobicContact CB-CG 3.61Å; F208-F256 HydrophobicContact CB-CZ 4.12Å; F208-F256 HydrophobicContact CD1-CD1 4.45Å; F208-F256 AromaticContact CD1-CD2 3.62Å; F208-F256 HydrophobicContact CD1-CD2 3.62Å; F208-F256 HydrophobicContact CD1-CE1 4.3Å; F208-F256 AromaticContact CD1-CE2 3.42Å; F208-F256 HydrophobicContact CD1-CE2 3.42Å; F208-F256 VanDerWaalsContact CD1-CE2 3.42Å; F208-F256 HydrophobicContact CD1-CG 4.12Å; F208-F256 AromaticContact CD1-CZ 3.79Å; F208-F256 HydrophobicContact CD1-CZ 3.79Å; F208-F256 HydrophobicContact CD2-CE1 4.17Å; F208-F256 HydrophobicContact CD2-CE2 4.49Å; F208-F256 HydrophobicContact CD2-CZ 4.02Å; F208-F256 HydrophobicContact CE1-CD2 4.38Å; F208-F256 AromaticContact CE1-CE2 3.82Å; F208-F256 HydrophobicContact CE1-CE2 3.82Å; F208-F256 HydrophobicContact CE1-CZ 4.19Å; F208-F256 HydrophobicContact CE2-CZ 4.41Å; F208-F256 HydrophobicContact CG-CD1 4.01Å; F208-F256 HydrophobicContact CG-CD2 4.02Å; F208-F256 AromaticContact CG-CE1 3.83Å; F208-F256 HydrophobicContact CG-CE1 3.83Å; F208-F256 AromaticContact CG-CE2 3.82Å; F208-F256 HydrophobicContact CG-CE2 3.82Å; F208-F256 HydrophobicContact CG-CG 4.09Å; F208-F256 AromaticContact CG-CZ 3.71Å; F208-F256 HydrophobicContact CG-CZ 3.71Å; F208-F256 HydrophobicContact CZ-CZ 4.48Å
209V98.8Very high97.9Very high0 Ų026.5 Ų26.50%012%0.12CC..  trans-85117.8170.9-177.90000109.7Y173 F199 L202 V203 S221 L226Y173-V209 HydrophobicContact CD1-CB 3.62Å; Y173-V209 HydrophobicContact CD1-CG1 3.72Å; Y173-V209 HydrophobicContact CD1-CG2 4.47Å; Y173-V209 HydrophobicContact CD2-CB 3.97Å; Y173-V209 HydrophobicContact CD2-CG1 3.57Å; Y173-V209 HydrophobicContact CD2-CG2 4.2Å; Y173-V209 HydrophobicContact CE1-CB 3.62Å; Y173-V209 HydrophobicContact CE1-CG1 4.18Å; Y173-V209 HydrophobicContact CE1-CG2 4.1Å; Y173-V209 HydrophobicContact CE2-CB 4.04Å; Y173-V209 HydrophobicContact CE2-CG1 4.11Å; Y173-V209 HydrophobicContact CE2-CG2 3.88Å; Y173-V209 HydrophobicContact CG-CB 3.8Å; Y173-V209 HydrophobicContact CG-CG1 3.38Å; F199-V209 HydrophobicContact CB-CG2 4.15Å; F199-V209 HydrophobicContact CD1-CB 4.47Å; F199-V209 HydrophobicContact CD1-CG1 3.43Å; F199-V209 VanDerWaalsContact CD1-CG1 3.43Å; F199-V209 HydrophobicContact CD1-CG2 4.16Å; F199-V209 HydrophobicContact CE1-CG1 3.81Å; F199-V209 HydrophobicContact CG-CG1 4.5Å; L202-V209 HydrophobicContact CD1-CG1 4.48Å; V203-V209 HydrophobicContact CG2-CG2 3.49Å; V203-V209 VanDerWaalsContact CG2-CG2 3.49Å; V209-S221 WeakPolarHBondContact O-CA 3.42Å; V209-S221 WeakPolarHBondContact O-CB 3.4Å; V209-S221 PolarHBondContact O-OG 3.07Å; V209-L226 HydrophobicContact CG2-CD2 3.99Å
210P98.5Very high97.8Very high0 Ų026.4 Ų26.40%012%0.12CC..  trans-59.7155.7172.4-21.934.1000112.1Y206 F208 G212 R220Y206-P210 HydrophobicContact CD2-CG 3.85Å; Y206-P210 HydrophobicContact CE2-CG 4.28Å; Y206-P210 HydrophobicContact CG-CG 4.22Å; F208-P210 HydrophobicContact CE2-CB 4.49Å; F208-P210 HydrophobicContact CE2-CG 4.45Å; F208-P210 WeakPolarHBondContact O-CD 3.45Å; P210-G212 PolarHBondContact O-N 3.43Å; P210-G212 VanDerWaalsContact O-N 3.17Å; P210-R220 CarbonylContact C-O 3.59Å; P210-R220 WeakPolarHBondContact CA-O 3.43Å
211N97.8Very high97.8Very high6 Ų626.2 Ų26.23%0.03212%0.119CC..SBendtrans-45.6-49.6178.5-178.2-51.6000112.2Y172 Y173 Y217 R220 S221 Q222 A315Y172-N211 WeakPolarHBondContact CD1-OD1 3.04Å; Y172-N211 WeakPolarHBondContact CE1-OD1 3.28Å; Y173-N211 PolarHBondContact N-O 3.15Å; Y173-N211 VanDerWaalsContact N-O 3.08Å; N211-Y217 HydrophobicContact CB-CD1 3.77Å; N211-Y217 HydrophobicContact CB-CE1 4.37Å; N211-Y217 HydrophobicContact CB-CG 3.91Å; N211-R220 HydrophobicContact CB-CG 4.05Å; N211-R220 PolarHBondContact N-O 2.88Å; N211-S221 WeakPolarHBondContact CA-O 3.25Å; N211-S221 VanDerWaalsContact CB-O 3.26Å; N211-S221 WeakPolarHBondContact CB-O 3.32Å; N211-Q222 HydrophobicContact CB-CG 4.3Å; N211-Q222 PolarHBondContact O-OE1 3.07Å; N211-Q222 PolarHBondContact OD1-NE2 3.43Å; N211-A315 PolarHBondContact ND2-O 3.11Å; N211-A315 VanDerWaalsContact ND2-O 3.08Å
212G96.8Very high97.8Very high0 Ų023.7 Ų23.70%011%0.108CC..BIsolated β-bridgetrans-147.5179.4169.500000112.6L171 P210 R214 Y217L171-G212 CarbonylContact O-C 3.57Å; L171-G212 WeakPolarHBondContact O-CA 3.32Å; P210-G212 PolarHBondContact O-N 3.43Å; P210-G212 VanDerWaalsContact O-N 3.17Å; G212-R214 PolarHBondContact O-N 3.34Å; G212-Y217 WeakPolarHBondContact O-CD2 3.18Å
213G96.6Very high97.8Very high0 Ų024 Ų240%011%0.11CC..SBendtrans-73.640.2-174.900000115.9Q154 I155 L171Q154-G213 VanDerWaalsContact CD-O 3.3Å; Q154-G213 PolarHBondContact NE2-O 3.22Å; I155-G213 PolarHBondContact N-O 2.75Å; L171-G213 PolarHBondContact O-N 3.38Å
214R97.9Very high97.8Very high2 Ų224 Ų241%0.00811%0.11CC..BIsolated β-bridgetrans-129.6146.1-178.8-64.1-86.4-178.1-172.7-2.3111.8D54 E99 S153 I155 E170 G212 Y216 Y217D54-R214 IonicContact OD1-CZ 2.67Å; D54-R214 IonicContact OD1-NE 3.21Å; D54-R214 PolarHBondContact OD1-NE 3.45Å; D54-R214 IonicContact OD1-NH1 3.48Å; D54-R214 IonicContact OD1-NH2 3.23Å; D54-R214 IonicContact OD2-CZ 3.26Å; D54-R214 IonicContact OD2-NH2 2.8Å; E99-R214 IonicContact OE1-CZ 3.29Å; E99-R214 IonicContact OE1-NH1 3.07Å; E99-R214 PolarHBondContact OE1-NH1 3.22Å; E99-R214 IonicContact OE1-NH2 3.08Å; E99-R214 PolarHBondContact OE1-NH2 2.8Å; S153-R214 CarbonylContact O-C 3.55Å; S153-R214 WeakPolarHBondContact O-CA 3.26Å; S153-R214 WeakPolarHBondContact OG-CD 3.42Å; S153-R214 PolarHBondContact OG-NH1 2.88Å; I155-R214 VanDerWaalsContact CD1-C 3.49Å; I155-R214 WeakPolarHBondContact CD1-O 3.44Å; E170-R214 HydrophobicContact CB-CG 4.49Å; E170-R214 HydrophobicContact CG-CG 4.01Å; E170-R214 IonicContact OE2-CZ 2.65Å; E170-R214 IonicContact OE2-NE 3.38Å; E170-R214 PolarHBondContact OE2-NE 3.25Å; E170-R214 IonicContact OE2-NH2 3.46Å; E170-R214 PolarHBondContact OE2-NH2 2.7Å; G212-R214 PolarHBondContact O-N 3.34Å; R214-Y216 HydrophobicContact CB-CD1 3.97Å; R214-Y216 HydrophobicContact CB-CD2 4.01Å; R214-Y216 HydrophobicContact CB-CE1 3.6Å; R214-Y216 HydrophobicContact CB-CE2 3.64Å; R214-Y216 HydrophobicContact CB-CG 4.17Å; R214-Y216 VanDerWaalsContact CB-CZ 3.43Å; R214-Y216 HydrophobicContact CG-CE1 3.89Å; R214-Y216 HydrophobicContact CG-CE2 4.05Å; R214-Y216 WeakPolarHBondContact CG-OH 3.39Å; R214-Y216 PolarHBondContact O-N 3.04Å; R214-Y217 HydrophobicContact CB-CD2 3.69Å; R214-Y217 HydrophobicContact CB-CE2 4.04Å; R214-Y217 HydrophobicContact CG-CD2 4.33Å; R214-Y217 HydrophobicContact CG-CE2 4.26Å; R214-Y217 WeakPolarHBondContact O-CB 3.15Å; R214-Y217 PolarHBondContact O-N 3.19Å
215V97.8Very high97.8Very high22 Ų2217.9 Ų17.913%0.1338%0.081CC..G310 helixtrans-59.4-33.2-178-63.90000112.4C26 Y31 S153 I155 Y217 E218C26-V215 HydrophobicContact CB-CB 4.41Å; C26-V215 WeakPolarHBondContact CB-O 3.37Å; Y31-V215 HydrophobicContact CD2-CG2 4.5Å; S153-V215 PolarHBondContact O-N 2.92Å; I155-V215 HydrophobicContact CG1-CG1 4.1Å; V215-Y217 PolarHBondContact O-N 3.31Å; V215-Y217 VanDerWaalsContact O-N 3.08Å; V215-E218 VanDerWaalsContact O-CB 3.29Å; V215-E218 WeakPolarHBondContact O-CB 3.4Å; V215-E218 WeakPolarHBondContact O-CG 3.43Å; V215-E218 PolarHBondContact O-N 3.1Å
216Y97.4Very high97.9Very high0 Ų012 Ų120%06%0.059CC..G310 helixtrans-69.4-3.217651.8-106.2000114.3C32 K50 V53 D54 R214 R220 E287C32-Y216 VanDerWaalsContact SG-CA 3.59Å; K50-Y216 WeakPolarHBondContact CE-OH 3.22Å; V53-Y216 HydrophobicContact CB-CD1 4.05Å; V53-Y216 HydrophobicContact CB-CE1 3.83Å; V53-Y216 HydrophobicContact CG2-CD1 4.16Å; V53-Y216 HydrophobicContact CG2-CE1 3.63Å; D54-Y216 PolarHBondContact OD1-OH 2.8Å; R214-Y216 HydrophobicContact CB-CD1 3.97Å; R214-Y216 HydrophobicContact CB-CD2 4.01Å; R214-Y216 HydrophobicContact CB-CE1 3.6Å; R214-Y216 HydrophobicContact CB-CE2 3.64Å; R214-Y216 HydrophobicContact CB-CG 4.17Å; R214-Y216 VanDerWaalsContact CB-CZ 3.43Å; R214-Y216 HydrophobicContact CG-CE1 3.89Å; R214-Y216 HydrophobicContact CG-CE2 4.05Å; R214-Y216 WeakPolarHBondContact CG-OH 3.39Å; R214-Y216 PolarHBondContact O-N 3.04Å; Y216-R220 PolarHBondContact O-NH1 3.23Å; Y216-E287 HydrophobicContact CD2-CB 4.43Å; Y216-E287 HydrophobicContact CE2-CB 4.01Å; Y216-E287 HydrophobicContact CE2-CG 4.41Å
217Y97.9Very high97.9Very high10 Ų109.9 Ų9.94%0.0395%0.051CC..G310 helixtrans-98.1-2.4170.6-63.4-48.9000114Y172 N211 G212 R214 V215 R219 R220Y172-Y217 HydrophobicContact CE1-CE2 4.28Å; Y172-Y217 PolarHBondContact OH-OH 2.93Å; N211-Y217 HydrophobicContact CB-CD1 3.77Å; N211-Y217 HydrophobicContact CB-CE1 4.37Å; N211-Y217 HydrophobicContact CB-CG 3.91Å; G212-Y217 WeakPolarHBondContact O-CD2 3.18Å; R214-Y217 HydrophobicContact CB-CD2 3.69Å; R214-Y217 HydrophobicContact CB-CE2 4.04Å; R214-Y217 HydrophobicContact CG-CD2 4.33Å; R214-Y217 HydrophobicContact CG-CE2 4.26Å; R214-Y217 WeakPolarHBondContact O-CB 3.15Å; R214-Y217 PolarHBondContact O-N 3.19Å; V215-Y217 PolarHBondContact O-N 3.31Å; V215-Y217 VanDerWaalsContact O-N 3.08Å; Y217-R219 PolarHBondContact O-N 3.35Å; Y217-R220 PolarHBondContact O-N 2.96Å
218E95.9Very high97.9Very high37 Ų378.8 Ų8.817%0.1734%0.04CC..THydrogen-bonded Turntrans-61.3-7.1-172.9-76.2-178.8166.400116.3I155 Y206 F208 V215I155-E218 HydrophobicContact CD1-CG 4.28Å; Y206-E218 HydrophobicContact CD1-CG 4.38Å; Y206-E218 HydrophobicContact CE1-CB 4.43Å; Y206-E218 HydrophobicContact CE1-CG 3.62Å; Y206-E218 WeakPolarHBondContact CE1-OE1 3.45Å; Y206-E218 PolarHBondContact OH-OE1 3Å; F208-E218 WeakPolarHBondContact CZ-O 3.11Å; V215-E218 VanDerWaalsContact O-CB 3.29Å; V215-E218 WeakPolarHBondContact O-CB 3.4Å; V215-E218 WeakPolarHBondContact O-CG 3.43Å; V215-E218 PolarHBondContact O-N 3.1Å
219R95.9Very high97.9Very high67 Ų678 Ų825%0.2534%0.037SC..THydrogen-bonded Turntrans-109.1-9178.4-60.3-64.6-175-167-1.2114.3P24 P25 Y27 Y217 R261 V279 A281P24-R219 PolarHBondContact O-NE 3.3Å; P25-R219 WeakPolarHBondContact O-CG 3.31Å; Y27-R219 PolarHBondContact OH-NH2 2.98Å; Y217-R219 PolarHBondContact O-N 3.35Å; R219-R261 PolarHBondContact O-NH2 3.47Å; R219-V279 HydrophobicContact CB-CG1 4.21Å; R219-A281 HydrophobicContact CB-CB 4.48Å
220R97.3Very high97.9Very high0 Ų08 Ų80%04%0.037CC..  trans-134.1140.9-176.766.6-178.9172.2-6911111.8P210 N211 Y216 Y217 V279 E287 K312 E316P210-R220 CarbonylContact C-O 3.59Å; P210-R220 WeakPolarHBondContact CA-O 3.43Å; N211-R220 HydrophobicContact CB-CG 4.05Å; N211-R220 PolarHBondContact N-O 2.88Å; Y216-R220 PolarHBondContact O-NH1 3.23Å; Y217-R220 PolarHBondContact O-N 2.96Å; R220-V279 HydrophobicContact CB-CB 4.49Å; R220-V279 HydrophobicContact CB-CG1 4.08Å; R220-V279 HydrophobicContact CB-CG2 3.56Å; R220-E287 IonicContact CZ-OE1 3.37Å; R220-E287 IonicContact NH2-OE1 3.81Å; R220-E287 PolarHBondContact NH2-OE1 2.79Å; R220-E287 IonicContact NH2-OE2 3.63Å; R220-E287 PolarHBondContact NH2-OE2 3.44Å; R220-K312 WeakPolarHBondContact CD-O 3.43Å; R220-E316 WeakPolarHBondContact CA-OE1 3.36Å; R220-E316 HydrophobicContact CB-CB 4.14Å; R220-E316 HydrophobicContact CB-CG 4.27Å
221S98.5Very high98Very high0 Ų011.2 Ų11.20%05%0.052CC..  trans-92-152.8174.8-165.40000110.9V209 N211 E316V209-S221 WeakPolarHBondContact O-CA 3.42Å; V209-S221 WeakPolarHBondContact O-CB 3.4Å; V209-S221 PolarHBondContact O-OG 3.07Å; N211-S221 WeakPolarHBondContact CA-O 3.25Å; N211-S221 VanDerWaalsContact CB-O 3.26Å; N211-S221 WeakPolarHBondContact CB-O 3.32Å; S221-E316 PolarHBondContact N-OE1 3.46Å
222Q98.3Very high98Very high8 Ų812 Ų124%0.0376%0.057CC..  trans-146.5174.9167.3-108.8-176.4-6.700107.4Y173 W174 N211 W257 E316Y173-Q222 HydrophobicContact CD1-CB 3.9Å; Y173-Q222 HydrophobicContact CG-CB 4.28Å; W174-Q222 VanDerWaalsContact N-OE1 3.14Å; N211-Q222 HydrophobicContact CB-CG 4.3Å; N211-Q222 PolarHBondContact O-OE1 3.07Å; N211-Q222 PolarHBondContact OD1-NE2 3.43Å; Q222-W257 VanDerWaalsContact O-CZ2 3.28Å; Q222-W257 WeakPolarHBondContact O-CZ2 3.32Å; Q222-E316 VanDerWaalsContact CA-O 3.26Å; Q222-E316 WeakPolarHBondContact CA-O 3.28Å
223P98.8Very high98.1Very high9 Ų912.4 Ų12.46%0.0586%0.059CC..SBendtrans-48.8129178.1-32.239.7000112.7W174 F225 F277 S317 L353W174-P223 HydrophobicContact CB-CB 4.17Å; W174-P223 HydrophobicContact CB-CG 4.46Å; W174-P223 HydrophobicContact CD2-CB 4.41Å; W174-P223 HydrophobicContact CD2-CG 3.96Å; W174-P223 HydrophobicContact CE3-CB 3.95Å; W174-P223 HydrophobicContact CE3-CG 3.6Å; W174-P223 HydrophobicContact CG-CG 4.34Å; W174-P223 HydrophobicContact CZ3-CG 4.12Å; P223-F225 HydrophobicContact CB-CD2 3.94Å; P223-F225 HydrophobicContact CB-CE2 3.78Å; P223-F225 WeakPolarHBondContact O-CD2 3.38Å; P223-F225 PolarHBondContact O-N 2.77Å; P223-F277 HydrophobicContact CG-CZ 4.34Å; P223-S317 VanDerWaalsContact CG-O 3.24Å; P223-S317 WeakPolarHBondContact CG-O 3.39Å; P223-L353 HydrophobicContact CB-CD2 3.8Å
224P98.6Very high98.2Very high0 Ų014.4 Ų14.40%07%0.067CC..  trans-7983.9-166.928.2-36.2000114.7Y173 W257 L350 L353 L354 N357Y173-P224 HydrophobicContact CE1-CB 4.4Å; Y173-P224 VanDerWaalsContact OH-CA 3.31Å; Y173-P224 WeakPolarHBondContact OH-CA 3.23Å; P224-W257 HydrophobicContact CB-CZ2 4.19Å; P224-W257 HydrophobicContact CG-CD2 4.21Å; P224-W257 HydrophobicContact CG-CZ2 4.04Å; P224-L350 HydrophobicContact CG-CD1 4.35Å; P224-L353 HydrophobicContact CG-CD2 4.04Å; P224-L353 HydrophobicContact CG-CG 4.26Å; P224-L354 HydrophobicContact CG-CD2 3.88Å; P224-L354 HydrophobicContact CG-CG 4.41Å; P224-N357 PolarHBondContact O-ND2 3.04Å
225F98.8Very high98.2Very high4 Ų417.4 Ų17.42%0.01810%0.099CC..  trans-91.9-2.4-179-83.1-98.6000115Y173 W174 Y177 W178 P223 L228 M229 L353 W423 M475Y173-F225 PolarHBondContact OH-N 3.36Å; W174-F225 HydrophobicContact CB-CD2 3.78Å; W174-F225 HydrophobicContact CB-CE2 4.23Å; W174-F225 HydrophobicContact CE3-CE2 4.19Å; Y177-F225 AromaticContact CD1-CD1 3.56Å; Y177-F225 HydrophobicContact CD1-CD1 3.56Å; Y177-F225 AromaticContact CD1-CE1 3.72Å; Y177-F225 HydrophobicContact CD1-CE1 3.72Å; Y177-F225 HydrophobicContact CD2-CD1 4.03Å; Y177-F225 HydrophobicContact CE1-CD1 4.12Å; Y177-F225 HydrophobicContact CE1-CE1 4.06Å; Y177-F225 HydrophobicContact CG-CB 4.36Å; Y177-F225 AromaticContact CG-CD1 3.5Å; Y177-F225 HydrophobicContact CG-CD1 3.5Å; Y177-F225 HydrophobicContact CG-CE1 4.16Å; Y177-F225 HydrophobicContact CG-CG 4.26Å; W178-F225 HydrophobicContact CH2-CE1 4.16Å; W178-F225 HydrophobicContact CH2-CE2 4.31Å; W178-F225 AromaticContact CH2-CZ 3.86Å; W178-F225 HydrophobicContact CH2-CZ 3.86Å; W178-F225 HydrophobicContact CZ2-CE1 4.3Å; W178-F225 HydrophobicContact CZ2-CZ 4.27Å; P223-F225 HydrophobicContact CB-CD2 3.94Å; P223-F225 HydrophobicContact CB-CE2 3.78Å; P223-F225 WeakPolarHBondContact O-CD2 3.38Å; P223-F225 PolarHBondContact O-N 2.77Å; F225-L228 HydrophobicContact CD1-CB 4.46Å; F225-L228 HydrophobicContact CD1-CD2 3.86Å; F225-L228 HydrophobicContact CE1-CD2 4.06Å; F225-L228 WeakPolarHBondContact O-CA 3.39Å; F225-L228 WeakPolarHBondContact O-CB 3.47Å; F225-L228 PolarHBondContact O-N 2.97Å; F225-M229 HydrophobicContact CB-CE 3.99Å; F225-M229 WeakPolarHBondContact O-CG 3.39Å; F225-M229 PolarHBondContact O-N 3.42Å; F225-L353 HydrophobicContact CD1-CD1 4.38Å; F225-L353 HydrophobicContact CD2-CD1 4.38Å; F225-L353 HydrophobicContact CD2-CD2 3.63Å; F225-L353 HydrophobicContact CE1-CD1 4.28Å; F225-L353 HydrophobicContact CE2-CD1 4.26Å; F225-L353 HydrophobicContact CE2-CD2 3.47Å; F225-L353 VanDerWaalsContact CE2-CD2 3.47Å; F225-L353 HydrophobicContact CG-CD1 4.43Å; F225-L353 HydrophobicContact CG-CD2 4.4Å; F225-L353 HydrophobicContact CZ-CD1 4.21Å; F225-L353 HydrophobicContact CZ-CD2 4.14Å; F225-W423 HydrophobicContact CD1-CH2 4.41Å; F225-W423 AromaticContact CE1-CH2 3.48Å; F225-W423 HydrophobicContact CE1-CH2 3.48Å; F225-W423 VanDerWaalsContact CE1-CH2 3.48Å; F225-W423 AromaticContact CE1-CZ2 3.82Å; F225-W423 HydrophobicContact CE1-CZ2 3.82Å; F225-W423 AromaticContact CZ-CH2 3.85Å; F225-W423 HydrophobicContact CZ-CH2 3.85Å; F225-W423 HydrophobicContact CZ-CZ2 4.43Å; F225-M475 HydrophobicContact CZ-SD 4.44Å
226L98.9Very high98.2Very high0 Ų019 Ų190%012%0.115CC..Hα-helixtrans-58.7-40.9-174.9-172.757.2000114.1Y173 I196 F199 L200 V203 V209 L228 M229 A230 L250 E253Y173-L226 HydrophobicContact CE2-CB 3.81Å; Y173-L226 WeakPolarHBondContact OH-CB 3.33Å; Y173-L226 PolarHBondContact OH-N 3.11Å; I196-L226 HydrophobicContact CG2-CD1 4.17Å; F199-L226 HydrophobicContact CB-CD1 3.45Å; F199-L226 VanDerWaalsContact CB-CD1 3.45Å; F199-L226 HydrophobicContact CB-CD2 4.05Å; F199-L226 HydrophobicContact CB-CG 4.35Å; F199-L226 HydrophobicContact CD2-CD1 4.26Å; F199-L226 HydrophobicContact CG-CD1 4.16Å; L200-L226 HydrophobicContact CD2-CD2 4.04Å; V203-L226 HydrophobicContact CG2-CD2 3.84Å; V209-L226 HydrophobicContact CG2-CD2 3.99Å; L226-L228 VanDerWaalsContact C-N 3.26Å; L226-L228 PolarHBondContact O-N 2.99Å; L226-M229 HydrophobicContact CD1-SD 3.99Å; L226-M229 PolarHBondContact O-N 3.02Å; L226-A230 PolarHBondContact O-N 3.17Å; L226-L250 HydrophobicContact CB-CD2 4.24Å; L226-L250 HydrophobicContact CD2-CD2 3.85Å; L226-L250 HydrophobicContact CG-CD2 3.54Å; L226-E253 WeakPolarHBondContact CB-OE2 3.47Å
227P98.8Very high98.3Very high3 Ų321.7 Ų21.72%0.01913%0.131CC..Hα-helixtrans-60.9-33.7173.1-26.337.4000113.4A230 E231 L250 N357 L360P227-A230 PolarHBondContact O-N 3.34Å; P227-E231 PolarHBondContact O-N 3.45Å; P227-L250 HydrophobicContact CG-CD2 4.38Å; P227-N357 HydrophobicContact CG-CB 4.23Å; P227-L360 HydrophobicContact CB-CB 4.43Å; P227-L360 HydrophobicContact CB-CD1 4.05Å
228L98.8Very high98.3Very high0 Ų023.3 Ų23.30%015%0.151CC..Hα-helixtrans-73-35.9176.5-71.378000111.5Y177 F225 L226 A230 E231 S232 L353 R356 N357 L360 W423Y177-L228 HydrophobicContact CD2-CB 3.94Å; Y177-L228 HydrophobicContact CE2-CB 3.57Å; Y177-L228 HydrophobicContact CE2-CD2 4.24Å; F225-L228 HydrophobicContact CD1-CB 4.46Å; F225-L228 HydrophobicContact CD1-CD2 3.86Å; F225-L228 HydrophobicContact CE1-CD2 4.06Å; F225-L228 WeakPolarHBondContact O-CA 3.39Å; F225-L228 WeakPolarHBondContact O-CB 3.47Å; F225-L228 PolarHBondContact O-N 2.97Å; L226-L228 VanDerWaalsContact C-N 3.26Å; L226-L228 PolarHBondContact O-N 2.99Å; L228-A230 VanDerWaalsContact C-N 3.33Å; L228-E231 WeakPolarHBondContact O-CB 3.41Å; L228-E231 PolarHBondContact O-N 3.33Å; L228-S232 PolarHBondContact O-N 3.28Å; L228-S232 PolarHBondContact O-OG 3.38Å; L228-L353 HydrophobicContact CD1-CD1 3.72Å; L228-L353 HydrophobicContact CD2-CD1 4.35Å; L228-R356 HydrophobicContact CD1-CG 4.49Å; L228-R356 VanDerWaalsContact CD2-CZ 3.49Å; L228-N357 WeakPolarHBondContact CD1-OD1 3.35Å; L228-L360 HydrophobicContact CB-CD1 4.46Å; L228-L360 HydrophobicContact CD1-CD1 3.86Å; L228-L360 HydrophobicContact CG-CD1 3.83Å; L228-W423 HydrophobicContact CD2-CH2 3.44Å; L228-W423 VanDerWaalsContact CD2-CH2 3.44Å; L228-W423 HydrophobicContact CD2-CZ2 3.61Å
229M98.9Very high98.4Very high0 Ų024.1 Ų24.10%016%0.156CC..Hα-helixtrans-63.1-42.2172.7-61.5166.9-171.200111.1Y173 Y177 I180 I196 F199 F225 L226 S232 Y233Y173-M229 HydrophobicContact CD2-CE 3.98Å; Y173-M229 HydrophobicContact CE2-CE 3.99Å; Y173-M229 WeakPolarHBondContact O-CE 3.39Å; Y177-M229 HydrophobicContact CD2-CG 4.07Å; I180-M229 HydrophobicContact CD1-CB 4.02Å; I180-M229 HydrophobicContact CD1-CE 4.48Å; I180-M229 HydrophobicContact CD1-CG 3.72Å; I180-M229 HydrophobicContact CD1-SD 3.58Å; I180-M229 VanDerWaalsContact CD1-SD 3.58Å; I196-M229 HydrophobicContact CD1-CB 4.28Å; I196-M229 WeakPolarHBondContact CD1-O 3.25Å; I196-M229 HydrophobicContact CG1-CB 4.07Å; F199-M229 HydrophobicContact CD2-CE 4.47Å; F199-M229 HydrophobicContact CD2-SD 3.75Å; F199-M229 HydrophobicContact CE2-CE 4.09Å; F199-M229 HydrophobicContact CE2-SD 3.84Å; F225-M229 HydrophobicContact CB-CE 3.99Å; F225-M229 WeakPolarHBondContact O-CG 3.39Å; F225-M229 PolarHBondContact O-N 3.42Å; L226-M229 HydrophobicContact CD1-SD 3.99Å; L226-M229 PolarHBondContact O-N 3.02Å; M229-S232 PolarHBondContact O-N 3.23Å; M229-Y233 PolarHBondContact O-N 2.88Å
230A98.8Very high98.4Very high0 Ų025.3 Ų25.30%017%0.165CC..Hα-helixtrans-63.8-38.6173.300000112.3L226 P227 L228 Y234 F242 L250 F364L226-A230 PolarHBondContact O-N 3.17Å; P227-A230 PolarHBondContact O-N 3.34Å; L228-A230 VanDerWaalsContact C-N 3.33Å; A230-Y234 VanDerWaalsContact O-CB 3.24Å; A230-Y234 WeakPolarHBondContact O-CB 3.36Å; A230-Y234 PolarHBondContact O-N 3.2Å; A230-F242 HydrophobicContact CB-CE1 4.12Å; A230-F242 HydrophobicContact CB-CZ 4.21Å; A230-L250 HydrophobicContact CB-CD1 4.01Å; A230-F364 HydrophobicContact CB-CE2 4.43Å; A230-F364 HydrophobicContact CB-CZ 4.49Å
231E98.8Very high98.5Very high68 Ų6833 Ų3332%0.31820%0.2SC..Hα-helixtrans-57.8-52.9171.6178.4-177.1-134.500110.8P227 L228 Y233 Y234 G235 R356 L360 F364P227-E231 PolarHBondContact O-N 3.45Å; L228-E231 WeakPolarHBondContact O-CB 3.41Å; L228-E231 PolarHBondContact O-N 3.33Å; E231-Y233 PolarHBondContact O-N 3.21Å; E231-Y234 PolarHBondContact O-N 2.82Å; E231-G235 PolarHBondContact O-N 3.49Å; E231-R356 IonicContact OE2-NH2 2.72Å; E231-R356 PolarHBondContact OE2-NH2 3.28Å; E231-R356 VanDerWaalsContact OE2-NH2 3.1Å; E231-L360 HydrophobicContact CB-CD1 4.35Å; E231-L360 HydrophobicContact CB-CD2 4.17Å; E231-L360 HydrophobicContact CG-CD2 4.04Å; E231-L360 WeakPolarHBondContact OE1-CD2 3.38Å; E231-F364 HydrophobicContact CB-CE1 4.4Å; E231-F364 HydrophobicContact CB-CZ 3.98Å
232S98.8Very high98.5Very high21 Ų2133.3 Ų33.315%0.14720%0.202CC..Hα-helixtrans-57.6-47.7-179.7-66.40000112.1N181 L228 M229 G235 A236N181-S232 VanDerWaalsContact OD1-CB 3.26Å; N181-S232 WeakPolarHBondContact OD1-CB 3.48Å; N181-S232 PolarHBondContact OD1-OG 2.64Å; L228-S232 PolarHBondContact O-N 3.28Å; L228-S232 PolarHBondContact O-OG 3.38Å; M229-S232 PolarHBondContact O-N 3.23Å; S232-G235 PolarHBondContact O-N 3.05Å; S232-A236 PolarHBondContact O-N 2.97Å
233Y98.8Very high98.5Very high9 Ų932.9 Ų32.94%0.03520%0.2CC..Hα-helixtrans-66.4-42.9179.3179-97.5000112.6T189 Y193 I196 M229 E231 G235 A236 T237 N239 F242T189-Y233 HydrophobicContact CG2-CD2 4.12Å; T189-Y233 HydrophobicContact CG2-CE2 3.55Å; Y193-Y233 AromaticContact CD2-CE1 3.77Å; Y193-Y233 HydrophobicContact CD2-CE1 3.77Å; Y193-Y233 HydrophobicContact CD2-CE2 4.04Å; Y193-Y233 AromaticContact CD2-CZ 3.45Å; Y193-Y233 VanDerWaalsContact CD2-CZ 3.45Å; Y193-Y233 VanDerWaalsContact CD2-OH 3.31Å; Y193-Y233 WeakPolarHBondContact CD2-OH 3.17Å; Y193-Y233 HydrophobicContact CE2-CE1 4.41Å; Y193-Y233 HydrophobicContact CG-CE2 4.26Å; I196-Y233 HydrophobicContact CD1-CD2 4.42Å; I196-Y233 HydrophobicContact CD1-CG 4.05Å; M229-Y233 PolarHBondContact O-N 2.88Å; E231-Y233 PolarHBondContact O-N 3.21Å; Y233-G235 VanDerWaalsContact C-N 3.34Å; Y233-A236 PolarHBondContact O-N 3Å; Y233-T237 HydrophobicContact CD2-CG2 4.12Å; Y233-T237 HydrophobicContact CE1-CG2 4.26Å; Y233-T237 HydrophobicContact CE2-CG2 3.69Å; Y233-T237 WeakPolarHBondContact O-CB 3.42Å; Y233-T237 WeakPolarHBondContact O-CG2 3.46Å; Y233-T237 PolarHBondContact O-N 3.39Å; Y233-T237 PolarHBondContact O-OG1 3.48Å; Y233-N239 HydrophobicContact CE1-CB 4.27Å; Y233-F242 AromaticContact CD1-CD1 3.38Å; Y233-F242 HydrophobicContact CD1-CD1 3.38Å; Y233-F242 HydrophobicContact CD1-CD2 4.45Å; Y233-F242 AromaticContact CD1-CE1 3.52Å; Y233-F242 HydrophobicContact CD1-CE1 3.52Å; Y233-F242 AromaticContact CD1-CG 3.87Å; Y233-F242 HydrophobicContact CD1-CG 3.87Å; Y233-F242 HydrophobicContact CD1-CZ 4.12Å; Y233-F242 HydrophobicContact CE1-CB 4.02Å; Y233-F242 AromaticContact CE1-CD1 3.66Å; Y233-F242 HydrophobicContact CE1-CD1 3.66Å; Y233-F242 HydrophobicContact CE1-CD2 4.27Å; Y233-F242 HydrophobicContact CE1-CE1 4.21Å; Y233-F242 AromaticContact CE1-CG 3.68Å; Y233-F242 HydrophobicContact CE1-CG 3.68Å; Y233-F242 HydrophobicContact CG-CE1 4.4Å
234Y98.6Very high98.5Very high42 Ų4239.9 Ų39.917%0.16523%0.225CC..Hα-helixtrans-63-42175.9177.7-103000111.4A230 E231 A236 T237 G238 Q240 L243 L367A230-Y234 VanDerWaalsContact O-CB 3.24Å; A230-Y234 WeakPolarHBondContact O-CB 3.36Å; A230-Y234 PolarHBondContact O-N 3.2Å; E231-Y234 PolarHBondContact O-N 2.82Å; Y234-A236 VanDerWaalsContact C-N 3.29Å; Y234-A236 PolarHBondContact O-N 2.96Å; Y234-T237 PolarHBondContact O-N 3.12Å; Y234-G238 WeakPolarHBondContact O-CA 3.27Å; Y234-G238 PolarHBondContact O-N 3.46Å; Y234-Q240 HydrophobicContact CE2-CG 3.86Å; Y234-L243 HydrophobicContact CD1-CD2 4.44Å; Y234-L243 HydrophobicContact CD2-CB 4.13Å; Y234-L243 HydrophobicContact CD2-CD2 4.03Å; Y234-L243 HydrophobicContact CE2-CD2 4.16Å; Y234-L243 HydrophobicContact CG-CD2 4.18Å; Y234-L367 HydrophobicContact CD1-CD1 4.49Å; Y234-L367 HydrophobicContact CE1-CD1 3.79Å
235G98.3Very high98.5Very high66 Ų6643 Ų4368%0.6825%0.25SS*.Hα-helixtrans-60-38.4176.400000112.8E231 S232 Y233E231-G235 PolarHBondContact O-N 3.49Å; S232-G235 PolarHBondContact O-N 3.05Å; Y233-G235 VanDerWaalsContact C-N 3.34Å
236A98.1Very high98.5Very high56 Ų5642.8 Ų42.846%0.46325%0.25SC..Hα-helixtrans-75.2-30.5178.800000114I184 S232 Y233 Y234I184-A236 HydrophobicContact CG2-CB 3.55Å; S232-A236 PolarHBondContact O-N 2.97Å; Y233-A236 PolarHBondContact O-N 3Å; Y234-A236 VanDerWaalsContact C-N 3.29Å; Y234-A236 PolarHBondContact O-N 2.96Å
237T98.1Very high98.5Very high55 Ų5543 Ų4334%0.33725%0.251SS..Hα-helixtrans-114.6-22.1-168.461.60000115T189 Y233 Y234 N239T189-T237 HydrophobicContact CG2-CG2 3.43Å; T189-T237 VanDerWaalsContact CG2-CG2 3.43Å; Y233-T237 HydrophobicContact CD2-CG2 4.12Å; Y233-T237 HydrophobicContact CE1-CG2 4.26Å; Y233-T237 HydrophobicContact CE2-CG2 3.69Å; Y233-T237 WeakPolarHBondContact O-CB 3.42Å; Y233-T237 WeakPolarHBondContact O-CG2 3.46Å; Y233-T237 PolarHBondContact O-N 3.39Å; Y233-T237 PolarHBondContact O-OG1 3.48Å; Y234-T237 PolarHBondContact O-N 3.12Å; T237-N239 PolarHBondContact O-N 3.47Å; T237-N239 VanDerWaalsContact OG1-CB 3.32Å; T237-N239 WeakPolarHBondContact OG1-CB 3.26Å; T237-N239 PolarHBondContact OG1-N 2.75Å
238G97.9Very high98.5Very high45 Ų4546.3 Ų46.346%0.46427%0.272SS..  trans6313.3-167.800000114.1Y234 Q240Y234-G238 WeakPolarHBondContact O-CA 3.27Å; Y234-G238 PolarHBondContact O-N 3.46Å; G238-Q240 PolarHBondContact O-N 3.16Å
239N98.1Very high98.5Very high53 Ų5347.3 Ų47.328%0.28328%0.278SS..  trans-73.189.4-170.8-170.8-22.4000112.2Y233 T237 Q241 F242 L243Y233-N239 HydrophobicContact CE1-CB 4.27Å; T237-N239 PolarHBondContact O-N 3.47Å; T237-N239 VanDerWaalsContact OG1-CB 3.32Å; T237-N239 WeakPolarHBondContact OG1-CB 3.26Å; T237-N239 PolarHBondContact OG1-N 2.75Å; N239-Q241 VanDerWaalsContact C-N 3.27Å; N239-Q241 PolarHBondContact O-N 3.1Å; N239-Q241 WeakPolarHBondContact OD1-CB 3.42Å; N239-Q241 PolarHBondContact OD1-N 3.17Å; N239-Q241 VanDerWaalsContact OD1-N 3.12Å; N239-F242 HydrophobicContact CB-CB 4.16Å; N239-F242 PolarHBondContact O-N 3.35Å; N239-F242 PolarHBondContact OD1-N 3.19Å; N239-L243 PolarHBondContact O-N 3.32Å
240Q97.4Very high98.5Very high93 Ų9347.4 Ų47.444%0.43528%0.278SS..Hα-helixtrans-65.9-26.8177.6-69.5-172.2-2.800113.3Y234 G238 L243 R244Y234-Q240 HydrophobicContact CE2-CG 3.86Å; G238-Q240 PolarHBondContact O-N 3.16Å; Q240-L243 PolarHBondContact O-N 2.87Å; Q240-R244 WeakPolarHBondContact O-CB 3.49Å; Q240-R244 PolarHBondContact O-N 3.45Å
241Q98.1Very high98.5Very high160 Ų16049.2 Ų49.275%0.74829%0.286SS*.Hα-helixtrans-68.3-44.9178.4-177.6178.28.600110.8N239 L243 R244 A245N239-Q241 VanDerWaalsContact C-N 3.27Å; N239-Q241 PolarHBondContact O-N 3.1Å; N239-Q241 WeakPolarHBondContact OD1-CB 3.42Å; N239-Q241 PolarHBondContact OD1-N 3.17Å; N239-Q241 VanDerWaalsContact OD1-N 3.12Å; Q241-L243 VanDerWaalsContact C-N 3.34Å; Q241-R244 PolarHBondContact O-N 2.03Å; Q241-A245 PolarHBondContact O-N 2.69Å; Q241-A245 VanDerWaalsContact O-N 3.09Å
242F98.4Very high98.5Very high7 Ų747.9 Ų47.93%0.03128%0.283CS..Hα-helixtrans-55.8-51171161.6-101.3000110.7Y193 I196 L200 A230 Y233 N239 R244 A245 A246Y193-F242 HydrophobicContact CD2-CD2 4.08Å; Y193-F242 HydrophobicContact CD2-CE2 4.42Å; Y193-F242 HydrophobicContact CE2-CB 4.47Å; Y193-F242 AromaticContact CE2-CD2 3.59Å; Y193-F242 HydrophobicContact CE2-CD2 3.59Å; Y193-F242 HydrophobicContact CE2-CE2 4.22Å; Y193-F242 HydrophobicContact CE2-CG 4.28Å; I196-F242 HydrophobicContact CG2-CE2 3.98Å; I196-F242 HydrophobicContact CG2-CZ 3.69Å; L200-F242 HydrophobicContact CD1-CE2 3.99Å; A230-F242 HydrophobicContact CB-CE1 4.12Å; A230-F242 HydrophobicContact CB-CZ 4.21Å; Y233-F242 AromaticContact CD1-CD1 3.38Å; Y233-F242 HydrophobicContact CD1-CD1 3.38Å; Y233-F242 HydrophobicContact CD1-CD2 4.45Å; Y233-F242 AromaticContact CD1-CE1 3.52Å; Y233-F242 HydrophobicContact CD1-CE1 3.52Å; Y233-F242 AromaticContact CD1-CG 3.87Å; Y233-F242 HydrophobicContact CD1-CG 3.87Å; Y233-F242 HydrophobicContact CD1-CZ 4.12Å; Y233-F242 HydrophobicContact CE1-CB 4.02Å; Y233-F242 AromaticContact CE1-CD1 3.66Å; Y233-F242 HydrophobicContact CE1-CD1 3.66Å; Y233-F242 HydrophobicContact CE1-CD2 4.27Å; Y233-F242 HydrophobicContact CE1-CE1 4.21Å; Y233-F242 AromaticContact CE1-CG 3.68Å; Y233-F242 HydrophobicContact CE1-CG 3.68Å; Y233-F242 HydrophobicContact CG-CE1 4.4Å; N239-F242 HydrophobicContact CB-CB 4.16Å; N239-F242 PolarHBondContact O-N 3.35Å; N239-F242 PolarHBondContact OD1-N 3.19Å; F242-R244 VanDerWaalsContact C-N 3.29Å; F242-R244 PolarHBondContact O-N 3.01Å; F242-A245 PolarHBondContact O-N 3.42Å; F242-A246 HydrophobicContact CE1-CB 4.41Å; F242-A246 HydrophobicContact CE2-CB 4.02Å; F242-A246 HydrophobicContact CZ-CB 3.96Å; F242-A246 WeakPolarHBondContact O-CB 3.46Å; F242-A246 PolarHBondContact O-N 3.37Å
243L98.1Very high98.5Very high0 Ų047 Ų470%028%0.277CS..Hα-helixtrans-60.3-41.1-177-171.961.9000111.9Y234 N239 Q240 Q241 A245 A246 L247 F364 L367 L368Y234-L243 HydrophobicContact CD1-CD2 4.44Å; Y234-L243 HydrophobicContact CD2-CB 4.13Å; Y234-L243 HydrophobicContact CD2-CD2 4.03Å; Y234-L243 HydrophobicContact CE2-CD2 4.16Å; Y234-L243 HydrophobicContact CG-CD2 4.18Å; N239-L243 PolarHBondContact O-N 3.32Å; Q240-L243 PolarHBondContact O-N 2.87Å; Q241-L243 VanDerWaalsContact C-N 3.34Å; L243-A245 VanDerWaalsContact C-N 3.32Å; L243-A245 PolarHBondContact O-N 3.4Å; L243-A246 PolarHBondContact O-N 3.31Å; L243-L247 VanDerWaalsContact O-CB 3.32Å; L243-L247 WeakPolarHBondContact O-CB 3.2Å; L243-L247 PolarHBondContact O-N 2.98Å; L243-F364 HydrophobicContact CD1-CB 4.22Å; L243-F364 HydrophobicContact CD1-CD1 3.79Å; L243-F364 HydrophobicContact CD1-CD2 3.86Å; L243-F364 HydrophobicContact CD1-CE1 4.01Å; L243-F364 HydrophobicContact CD1-CE2 4.07Å; L243-F364 HydrophobicContact CD1-CG 3.7Å; L243-F364 HydrophobicContact CD1-CZ 4.14Å; L243-F364 HydrophobicContact CD2-CB 4.2Å; L243-F364 HydrophobicContact CD2-CD1 3.83Å; L243-F364 HydrophobicContact CD2-CE1 4.48Å; L243-F364 HydrophobicContact CD2-CG 4.16Å; L243-F364 HydrophobicContact CG-CB 4.39Å; L243-F364 HydrophobicContact CG-CD1 4.37Å; L243-F364 HydrophobicContact CG-CG 4.33Å; L243-L367 HydrophobicContact CD2-CD1 4.37Å; L243-L368 HydrophobicContact CG-CD1 4.44Å
244R98.6Very high98.5Very high156 Ų15648 Ų4859%0.58928%0.28SS*.Hα-helixtrans-62.1-37.4175.8-172.9179.6-63.5158.93.4112.7Q240 Q241 F242 P248 L368Q240-R244 WeakPolarHBondContact O-CB 3.49Å; Q240-R244 PolarHBondContact O-N 3.45Å; Q241-R244 PolarHBondContact O-N 2.03Å; F242-R244 VanDerWaalsContact C-N 3.29Å; F242-R244 PolarHBondContact O-N 3.01Å; R244-P248 WeakPolarHBondContact O-CD 3.23Å; R244-L368 HydrophobicContact CB-CD1 4.14Å; R244-L368 HydrophobicContact CB-CD2 4.18Å
245A98.6Very high98.5Very high64 Ų6451.7 Ų51.753%0.52929%0.294SS..Hα-helixtrans-74.8-39.4177.400000112.3Q241 F242 L243Q241-A245 PolarHBondContact O-N 2.69Å; Q241-A245 VanDerWaalsContact O-N 3.09Å; F242-A245 PolarHBondContact O-N 3.42Å; L243-A245 VanDerWaalsContact C-N 3.32Å; L243-A245 PolarHBondContact O-N 3.4Å
246A98.8Very high98.5Very high0 Ų049.4 Ų49.40%027%0.266CS..Hα-helixtrans-73.6-36.8-177.600000112.9L200 F242 L243 I249 L250L200-A246 HydrophobicContact CD1-CB 3.78Å; L200-A246 HydrophobicContact CD2-CB 4.04Å; F242-A246 HydrophobicContact CE1-CB 4.41Å; F242-A246 HydrophobicContact CE2-CB 4.02Å; F242-A246 HydrophobicContact CZ-CB 3.96Å; F242-A246 WeakPolarHBondContact O-CB 3.46Å; F242-A246 PolarHBondContact O-N 3.37Å; L243-A246 PolarHBondContact O-N 3.31Å; A246-I249 WeakPolarHBondContact O-CA 3.47Å; A246-I249 WeakPolarHBondContact O-CB 3.24Å; A246-I249 PolarHBondContact O-N 2.63Å; A246-L250 WeakPolarHBondContact O-CG 3.29Å; A246-L250 PolarHBondContact O-N 2.85Å
247L98.8Very high98.5Very high6 Ų646.8 Ų46.83%0.03124%0.244CC..Hα-helixtrans-53.6-47.9-168.6-178.458.4000114.6L243 I249 L250 E251 L361 F364 L368L243-L247 VanDerWaalsContact O-CB 3.32Å; L243-L247 WeakPolarHBondContact O-CB 3.2Å; L243-L247 PolarHBondContact O-N 2.98Å; L247-I249 PolarHBondContact O-N 3.43Å; L247-L250 WeakPolarHBondContact O-CB 3.18Å; L247-L250 PolarHBondContact O-N 2.81Å; L247-L250 VanDerWaalsContact O-N 3.15Å; L247-E251 HydrophobicContact CD1-CG 4.37Å; L247-E251 WeakPolarHBondContact O-CG 3.3Å; L247-E251 PolarHBondContact O-N 2.93Å; L247-L361 HydrophobicContact CD1-CD2 3.64Å; L247-F364 HydrophobicContact CD1-CB 3.91Å; L247-F364 HydrophobicContact CD1-CD2 4.14Å; L247-F364 HydrophobicContact CD2-CB 4.13Å; L247-L368 HydrophobicContact CD2-CD1 3.76Å
248P98.8Very high98.6Very high71 Ų7146.5 Ų46.546%0.46124%0.239SC..Hα-helixtrans-61.4-28.8177.8-2334.7000114R244 T252R244-P248 WeakPolarHBondContact O-CD 3.23Å; P248-T252 PolarHBondContact O-N 2.94Å; P248-T252 VanDerWaalsContact O-N 3.17Å; P248-T252 PolarHBondContact O-OG1 2.58Å
249I98.9Very high98.6Very high22 Ų2250.9 Ų50.911%0.11325%0.247CC..Hα-helixtrans-76.2-42.7177.9-55.7171.2000109.3L200 V203 E204 A246 L247 E251 T252 E253L200-I249 HydrophobicContact CB-CD1 4.03Å; L200-I249 HydrophobicContact CB-CG2 4.16Å; L200-I249 HydrophobicContact CD2-CB 3.86Å; L200-I249 HydrophobicContact CD2-CD1 4.31Å; L200-I249 HydrophobicContact CD2-CG2 3.71Å; V203-I249 HydrophobicContact CB-CG2 3.56Å; V203-I249 HydrophobicContact CG1-CG2 3.53Å; V203-I249 WeakPolarHBondContact CG1-O 3.44Å; V203-I249 HydrophobicContact CG2-CG2 4.42Å; E204-I249 HydrophobicContact CG-CD1 3.86Å; E204-I249 HydrophobicContact CG-CG1 4.06Å; E204-I249 HydrophobicContact CG-CG2 4.23Å; E204-I249 WeakPolarHBondContact OE1-CD1 3.22Å; A246-I249 WeakPolarHBondContact O-CA 3.47Å; A246-I249 WeakPolarHBondContact O-CB 3.24Å; A246-I249 PolarHBondContact O-N 2.63Å; L247-I249 PolarHBondContact O-N 3.43Å; I249-E251 VanDerWaalsContact C-N 3.27Å; I249-E251 PolarHBondContact O-N 3.47Å; I249-T252 WeakPolarHBondContact O-CA 3.44Å; I249-T252 VanDerWaalsContact O-CB 3.26Å; I249-T252 WeakPolarHBondContact O-CB 3.4Å; I249-T252 PolarHBondContact O-N 3.33Å; I249-E253 PolarHBondContact O-N 2.87Å; I249-E253 VanDerWaalsContact O-N 3.12Å
250L98.9Very high98.6Very high1 Ų152.2 Ų52.21%0.00526%0.255CS..Hα-helixtrans-57.3-40.8172.3-57.8180000111.8L200 L226 P227 A230 A246 L247 T252 E253 Y254 L361 F364L200-L250 HydrophobicContact CD2-CD2 4.08Å; L226-L250 HydrophobicContact CB-CD2 4.24Å; L226-L250 HydrophobicContact CD2-CD2 3.85Å; L226-L250 HydrophobicContact CG-CD2 3.54Å; P227-L250 HydrophobicContact CG-CD2 4.38Å; A230-L250 HydrophobicContact CB-CD1 4.01Å; A246-L250 WeakPolarHBondContact O-CG 3.29Å; A246-L250 PolarHBondContact O-N 2.85Å; L247-L250 WeakPolarHBondContact O-CB 3.18Å; L247-L250 PolarHBondContact O-N 2.81Å; L247-L250 VanDerWaalsContact O-N 3.15Å; L250-T252 VanDerWaalsContact C-N 3.26Å; L250-T252 PolarHBondContact O-N 2.86Å; L250-E253 PolarHBondContact O-N 2.98Å; L250-Y254 PolarHBondContact O-N 2.83Å; L250-L361 HydrophobicContact CB-CD2 3.91Å; L250-F364 HydrophobicContact CD1-CD2 4.08Å; L250-F364 HydrophobicContact CD1-CE2 3.87Å
251E98.8Very high98.6Very high39 Ų3948.6 Ų48.618%0.18224%0.237CC..Hα-helixtrans-66.2-29.2175.2-65.7-175114.300112.6L247 I249 R255 L361 H365 Y377L247-E251 HydrophobicContact CD1-CG 4.37Å; L247-E251 WeakPolarHBondContact O-CG 3.3Å; L247-E251 PolarHBondContact O-N 2.93Å; I249-E251 VanDerWaalsContact C-N 3.27Å; I249-E251 PolarHBondContact O-N 3.47Å; E251-R255 WeakPolarHBondContact O-CB 3.32Å; E251-R255 WeakPolarHBondContact O-CG 3.27Å; E251-R255 PolarHBondContact O-N 3.25Å; E251-L361 HydrophobicContact CG-CD2 4.13Å; E251-H365 IonicContact OE1-CD2 2.83Å; E251-H365 IonicContact OE1-CE1 3.74Å; E251-H365 IonicContact OE1-NE2 3.16Å; E251-H365 PolarHBondContact OE1-NE2 3.48Å; E251-H365 IonicContact OE2-CE1 3.49Å; E251-H365 IonicContact OE2-NE2 2.83Å; E251-Y377 HydrophobicContact CG-CE2 4.46Å; E251-Y377 VanDerWaalsContact CG-OH 3.26Å; E251-Y377 WeakPolarHBondContact CG-OH 3.47Å; E251-Y377 WeakPolarHBondContact OE1-CE2 3.46Å; E251-Y377 VanDerWaalsContact OE1-CZ 3.3Å; E251-Y377 PolarHBondContact OE1-OH 3.03Å
252T98.9Very high98.6Very high40 Ų4043.1 Ų43.125%0.24522%0.216CC..Hα-helixtrans-67.6-46.8175.5-63.80000111.2V203 P248 I249 L250 R255 F256V203-T252 HydrophobicContact CG1-CG2 4.04Å; P248-T252 PolarHBondContact O-N 2.94Å; P248-T252 VanDerWaalsContact O-N 3.17Å; P248-T252 PolarHBondContact O-OG1 2.58Å; I249-T252 WeakPolarHBondContact O-CA 3.44Å; I249-T252 VanDerWaalsContact O-CB 3.26Å; I249-T252 WeakPolarHBondContact O-CB 3.4Å; I249-T252 PolarHBondContact O-N 3.33Å; L250-T252 VanDerWaalsContact C-N 3.26Å; L250-T252 PolarHBondContact O-N 2.86Å; T252-R255 PolarHBondContact O-N 3.16Å; T252-R255 PolarHBondContact OG1-NH2 3.32Å; T252-F256 PolarHBondContact O-N 2.64Å; T252-F256 VanDerWaalsContact O-N 3.09Å
253E98.9Very high98.6Very high3 Ų345 Ų451%0.01423%0.226CC..Hα-helixtrans-63.5-42.9174.2-176.3-179.3-149.200111.9Y173 V203 F208 L226 I249 L250 R255 F256 W257Y173-E253 WeakPolarHBondContact CE1-OE1 3.41Å; Y173-E253 PolarHBondContact OH-OE1 3.15Å; Y173-E253 PolarHBondContact OH-OE2 3.43Å; V203-E253 HydrophobicContact CG1-CB 3.98Å; V203-E253 HydrophobicContact CG2-CB 4.08Å; F208-E253 HydrophobicContact CB-CG 4.46Å; L226-E253 WeakPolarHBondContact CB-OE2 3.47Å; I249-E253 PolarHBondContact O-N 2.87Å; I249-E253 VanDerWaalsContact O-N 3.12Å; L250-E253 PolarHBondContact O-N 2.98Å; E253-R255 VanDerWaalsContact C-N 3.28Å; E253-R255 PolarHBondContact O-N 2.9Å; E253-F256 WeakPolarHBondContact O-CB 3.36Å; E253-F256 PolarHBondContact O-N 3.22Å; E253-F256 VanDerWaalsContact O-N 3.08Å; E253-W257 VanDerWaalsContact O-CD1 3.25Å; E253-W257 PolarHBondContact O-N 3.31Å; E253-W257 VanDerWaalsContact O-N 3.16Å
254Y98.9Very high98.6Very high29 Ų2948.6 Ų48.611%0.11425%0.248CC..Hα-helixtrans-58-41.4175.5173.8-101.6000111.9L250 F256 W257 M258 L354 E358 L361 Y377L250-Y254 PolarHBondContact O-N 2.83Å; Y254-F256 VanDerWaalsContact C-N 3.34Å; Y254-F256 PolarHBondContact O-N 3.43Å; Y254-W257 PolarHBondContact O-N 3.05Å; Y254-M258 HydrophobicContact CD1-CG 4.23Å; Y254-M258 HydrophobicContact CD2-CG 4.39Å; Y254-M258 HydrophobicContact CE1-CG 3.69Å; Y254-M258 HydrophobicContact CE2-CG 3.87Å; Y254-M258 HydrophobicContact CE2-SD 4.02Å; Y254-M258 VanDerWaalsContact CZ-CG 3.49Å; Y254-M258 WeakPolarHBondContact O-CG 3.47Å; Y254-M258 PolarHBondContact O-N 3.29Å; Y254-L354 HydrophobicContact CD2-CD2 4.48Å; Y254-E358 HydrophobicContact CD2-CG 4.5Å; Y254-E358 HydrophobicContact CE2-CG 3.53Å; Y254-E358 PolarHBondContact OH-OE1 2.9Å; Y254-L361 HydrophobicContact CD1-CD1 4.22Å; Y254-L361 HydrophobicContact CD2-CD1 4.25Å; Y254-L361 HydrophobicContact CG-CD1 3.85Å; Y254-Y377 AromaticContact CD1-CE1 3.72Å; Y254-Y377 HydrophobicContact CD1-CE1 3.72Å; Y254-Y377 HydrophobicContact CE1-CD1 4.25Å; Y254-Y377 AromaticContact CE1-CE1 3.63Å; Y254-Y377 HydrophobicContact CE1-CE1 3.63Å
255R98.8Very high98.5Very high119 Ų11941.8 Ų41.845%0.44922%0.224SC..Hα-helixtrans-61.8-39.4174.5-77.4-177.2-60.3124.3-2.8112.3E251 T252 E253 W257 M258 Q259E251-R255 WeakPolarHBondContact O-CB 3.32Å; E251-R255 WeakPolarHBondContact O-CG 3.27Å; E251-R255 PolarHBondContact O-N 3.25Å; T252-R255 PolarHBondContact O-N 3.16Å; T252-R255 PolarHBondContact OG1-NH2 3.32Å; E253-R255 VanDerWaalsContact C-N 3.28Å; E253-R255 PolarHBondContact O-N 2.9Å; R255-W257 VanDerWaalsContact C-N 3.35Å; R255-W257 PolarHBondContact O-N 3.43Å; R255-M258 PolarHBondContact O-N 3.26Å; R255-Q259 VanDerWaalsContact O-CB 3.29Å; R255-Q259 WeakPolarHBondContact O-CB 3Å; R255-Q259 VanDerWaalsContact O-CG 3.24Å; R255-Q259 WeakPolarHBondContact O-CG 3.24Å; R255-Q259 PolarHBondContact O-N 2.97Å
256F98.8Very high98.3Very high19 Ų1943.2 Ų43.28%0.08323%0.226CC..Hα-helixtrans-55.8-49.1173.3162.9-93.9000111.4G207 F208 T252 E253 Y254 M258 Q259 N260 R261G207-F256 WeakPolarHBondContact O-CB 3.42Å; F208-F256 HydrophobicContact CB-CB 4.15Å; F208-F256 HydrophobicContact CB-CD1 3.47Å; F208-F256 VanDerWaalsContact CB-CD1 3.47Å; F208-F256 HydrophobicContact CB-CD2 4.03Å; F208-F256 HydrophobicContact CB-CE1 3.75Å; F208-F256 HydrophobicContact CB-CE2 4.27Å; F208-F256 HydrophobicContact CB-CG 3.61Å; F208-F256 HydrophobicContact CB-CZ 4.12Å; F208-F256 HydrophobicContact CD1-CD1 4.45Å; F208-F256 AromaticContact CD1-CD2 3.62Å; F208-F256 HydrophobicContact CD1-CD2 3.62Å; F208-F256 HydrophobicContact CD1-CE1 4.3Å; F208-F256 AromaticContact CD1-CE2 3.42Å; F208-F256 HydrophobicContact CD1-CE2 3.42Å; F208-F256 VanDerWaalsContact CD1-CE2 3.42Å; F208-F256 HydrophobicContact CD1-CG 4.12Å; F208-F256 AromaticContact CD1-CZ 3.79Å; F208-F256 HydrophobicContact CD1-CZ 3.79Å; F208-F256 HydrophobicContact CD2-CE1 4.17Å; F208-F256 HydrophobicContact CD2-CE2 4.49Å; F208-F256 HydrophobicContact CD2-CZ 4.02Å; F208-F256 HydrophobicContact CE1-CD2 4.38Å; F208-F256 AromaticContact CE1-CE2 3.82Å; F208-F256 HydrophobicContact CE1-CE2 3.82Å; F208-F256 HydrophobicContact CE1-CZ 4.19Å; F208-F256 HydrophobicContact CE2-CZ 4.41Å; F208-F256 HydrophobicContact CG-CD1 4.01Å; F208-F256 HydrophobicContact CG-CD2 4.02Å; F208-F256 AromaticContact CG-CE1 3.83Å; F208-F256 HydrophobicContact CG-CE1 3.83Å; F208-F256 AromaticContact CG-CE2 3.82Å; F208-F256 HydrophobicContact CG-CE2 3.82Å; F208-F256 HydrophobicContact CG-CG 4.09Å; F208-F256 AromaticContact CG-CZ 3.71Å; F208-F256 HydrophobicContact CG-CZ 3.71Å; F208-F256 HydrophobicContact CZ-CZ 4.48Å; T252-F256 PolarHBondContact O-N 2.64Å; T252-F256 VanDerWaalsContact O-N 3.09Å; E253-F256 WeakPolarHBondContact O-CB 3.36Å; E253-F256 PolarHBondContact O-N 3.22Å; E253-F256 VanDerWaalsContact O-N 3.08Å; Y254-F256 VanDerWaalsContact C-N 3.34Å; Y254-F256 PolarHBondContact O-N 3.43Å; F256-M258 VanDerWaalsContact C-N 3.32Å; F256-M258 PolarHBondContact O-N 3.13Å; F256-Q259 PolarHBondContact O-N 2.97Å; F256-N260 HydrophobicContact CD2-CB 4.02Å; F256-N260 HydrophobicContact CE2-CB 3.94Å; F256-N260 VanDerWaalsContact O-CB 3.29Å; F256-N260 WeakPolarHBondContact O-CB 3.3Å; F256-N260 PolarHBondContact O-N 2.99Å; F256-N260 PolarHBondContact O-OD1 3.42Å; F256-R261 HydrophobicContact CE1-CG 4.35Å
257W98.9Very high97.8Very high1 Ų144 Ų440%0.00423%0.232CC..Hα-helixtrans-59.6-44.7177.3-73.896.7000111.6Q222 P224 E253 Y254 R255 Q259 R261 S262 N275 F277 E316 L350 L354Q222-W257 VanDerWaalsContact O-CZ2 3.28Å; Q222-W257 WeakPolarHBondContact O-CZ2 3.32Å; P224-W257 HydrophobicContact CB-CZ2 4.19Å; P224-W257 HydrophobicContact CG-CD2 4.21Å; P224-W257 HydrophobicContact CG-CZ2 4.04Å; E253-W257 VanDerWaalsContact O-CD1 3.25Å; E253-W257 PolarHBondContact O-N 3.31Å; E253-W257 VanDerWaalsContact O-N 3.16Å; Y254-W257 PolarHBondContact O-N 3.05Å; R255-W257 VanDerWaalsContact C-N 3.35Å; R255-W257 PolarHBondContact O-N 3.43Å; W257-Q259 PolarHBondContact O-N 2.86Å; W257-R261 HydrophobicContact CD2-CG 4.42Å; W257-R261 HydrophobicContact CE3-CB 3.67Å; W257-R261 HydrophobicContact CE3-CG 3.64Å; W257-R261 HydrophobicContact CZ3-CB 4.14Å; W257-R261 HydrophobicContact CZ3-CG 3.84Å; W257-R261 CarbonylContact O-C 3.46Å; W257-R261 WeakPolarHBondContact O-CA 3.28Å; W257-R261 WeakPolarHBondContact O-CB 2.93Å; W257-R261 PolarHBondContact O-N 2.83Å; W257-S262 PolarHBondContact O-N 2.88Å; W257-N275 PolarHBondContact O-ND2 2.71Å; W257-F277 AromaticContact CH2-CD1 3.97Å; W257-F277 HydrophobicContact CH2-CD1 3.97Å; W257-F277 AromaticContact CH2-CE1 3.75Å; W257-F277 HydrophobicContact CH2-CE1 3.75Å; W257-F277 AromaticContact CZ3-CD1 3.97Å; W257-F277 HydrophobicContact CZ3-CD1 3.97Å; W257-F277 AromaticContact CZ3-CE1 3.95Å; W257-F277 HydrophobicContact CZ3-CE1 3.95Å; W257-E316 HydrophobicContact CH2-CG 4.5Å; W257-L350 HydrophobicContact CE3-CD1 3.91Å; W257-L350 HydrophobicContact CE3-CD2 4.41Å; W257-L350 HydrophobicContact CH2-CD1 4.16Å; W257-L350 HydrophobicContact CZ3-CD1 3.65Å; W257-L350 HydrophobicContact CZ3-CD2 4.01Å; W257-L350 HydrophobicContact CZ3-CG 4.48Å; W257-L354 HydrophobicContact CB-CD1 4.44Å; W257-L354 HydrophobicContact CB-CD2 3.99Å; W257-L354 HydrophobicContact CG-CD2 4.03Å
258M98.8Very high97Very high48 Ų4849.5 Ų49.524%0.23627%0.267CS..Hα-helixtrans-68.6-30.9-179.9-63.8-47.7-63.700113.9Y254 R255 F256 S262 V273 R384Y254-M258 HydrophobicContact CD1-CG 4.23Å; Y254-M258 HydrophobicContact CD2-CG 4.39Å; Y254-M258 HydrophobicContact CE1-CG 3.69Å; Y254-M258 HydrophobicContact CE2-CG 3.87Å; Y254-M258 HydrophobicContact CE2-SD 4.02Å; Y254-M258 VanDerWaalsContact CZ-CG 3.49Å; Y254-M258 WeakPolarHBondContact O-CG 3.47Å; Y254-M258 PolarHBondContact O-N 3.29Å; R255-M258 PolarHBondContact O-N 3.26Å; F256-M258 VanDerWaalsContact C-N 3.32Å; F256-M258 PolarHBondContact O-N 3.13Å; M258-S262 VanDerWaalsContact O-CB 3.27Å; M258-S262 WeakPolarHBondContact O-CB 2.98Å; M258-S262 PolarHBondContact O-OG 2.84Å; M258-V273 HydrophobicContact CE-CG1 4.2Å; M258-R384 PolarHBondContact SD-NH2 2.66Å
259Q98.2Very high96.5Very high137 Ų13749.8 Ų49.864%0.6428%0.282SS*.Hα-helixtrans-90.1-37.1-177.1-70.3176-11.600112.8R255 F256 W257R255-Q259 VanDerWaalsContact O-CB 3.29Å; R255-Q259 WeakPolarHBondContact O-CB 3Å; R255-Q259 VanDerWaalsContact O-CG 3.24Å; R255-Q259 WeakPolarHBondContact O-CG 3.24Å; R255-Q259 PolarHBondContact O-N 2.97Å; F256-Q259 PolarHBondContact O-N 2.97Å; W257-Q259 PolarHBondContact O-N 2.86Å
260N97.9Very high96.2Very high82 Ų8251.6 Ų51.644%0.43930%0.297SS..Hα-helixtrans-110.1-12.4-168.2-60.581.1000113.6F256F256-N260 HydrophobicContact CD2-CB 4.02Å; F256-N260 HydrophobicContact CE2-CB 3.94Å; F256-N260 VanDerWaalsContact O-CB 3.29Å; F256-N260 WeakPolarHBondContact O-CB 3.3Å; F256-N260 PolarHBondContact O-N 2.99Å; F256-N260 PolarHBondContact O-OD1 3.42Å
261R98.2Very high96.1Very high17 Ų1758.7 Ų58.76%0.06433%0.33CS..SBendtrans-129.92.5-174.7-60.3-65.6-176.3-86.50.5113.8R219 F256 W257 N275 R276 N278 E316R219-R261 PolarHBondContact O-NH2 3.47Å; F256-R261 HydrophobicContact CE1-CG 4.35Å; W257-R261 HydrophobicContact CD2-CG 4.42Å; W257-R261 HydrophobicContact CE3-CB 3.67Å; W257-R261 HydrophobicContact CE3-CG 3.64Å; W257-R261 HydrophobicContact CZ3-CB 4.14Å; W257-R261 HydrophobicContact CZ3-CG 3.84Å; W257-R261 CarbonylContact O-C 3.46Å; W257-R261 WeakPolarHBondContact O-CA 3.28Å; W257-R261 WeakPolarHBondContact O-CB 2.93Å; W257-R261 PolarHBondContact O-N 2.83Å; R261-N275 CarbonylContact O-C 3.47Å; R261-N275 WeakPolarHBondContact O-CA 3.21Å; R261-N275 WeakPolarHBondContact O-CB 3.38Å; R261-N275 PolarHBondContact O-ND2 2.81Å; R261-R276 WeakPolarHBondContact CB-O 3.32Å; R261-R276 PolarHBondContact O-N 2.73Å; R261-N278 WeakPolarHBondContact CD-O 3.36Å; R261-N278 PolarHBondContact NE-O 3.2Å; R261-N278 PolarHBondContact NH1-O 3.36Å; R261-N278 VanDerWaalsContact NH1-O 3.16Å; R261-N278 PolarHBondContact NH2-O 2.86Å; R261-E316 IonicContact CZ-OE1 3.09Å; R261-E316 IonicContact CZ-OE2 2.78Å; R261-E316 IonicContact NE-OE1 3.88Å; R261-E316 PolarHBondContact NE-OE1 2.83Å; R261-E316 IonicContact NE-OE2 3.23Å; R261-E316 PolarHBondContact NE-OE2 2.98Å; R261-E316 IonicContact NH2-OE1 3.15Å; R261-E316 PolarHBondContact NH2-OE1 3.43Å; R261-E316 IonicContact NH2-OE2 3.74Å
262S98.3Very high96.1Very high44 Ų4457.4 Ų57.431%0.30832%0.324SS..EExtended strand (participates in β ladder)trans-91.3155178770000112.5W257 M258 L274W257-S262 PolarHBondContact O-N 2.88Å; M258-S262 VanDerWaalsContact O-CB 3.27Å; M258-S262 WeakPolarHBondContact O-CB 2.98Å; M258-S262 PolarHBondContact O-OG 2.84Å; S262-L274 CarbonylContact C-O 3.58Å; S262-L274 VanDerWaalsContact CA-O 3.31Å; S262-L274 WeakPolarHBondContact CA-O 3.12Å
263I98.4Very high96Very high46 Ų4658.5 Ų58.524%0.23633%0.33CS..EExtended strand (participates in β ladder)trans-143.3144.1172.3-173.3168.8000109.4V265 V273 L274 L346 L405I263-V265 HydrophobicContact CG1-CG2 4.5Å; I263-V265 HydrophobicContact CG2-CG2 4.18Å; I263-V273 WeakPolarHBondContact O-CA 3.37Å; I263-L274 PolarHBondContact N-O 3.42Å; I263-L274 PolarHBondContact O-N 2.94Å; I263-L346 HydrophobicContact CG2-CD2 3.61Å; I263-L405 HydrophobicContact CD1-CD1 4.14Å
264T98Very high96Very high76 Ų7658.3 Ų58.347%0.46633%0.33SS..EExtended strand (participates in β ladder)trans-89.4127.7171.5-56.70000109.8E271 H272T264-E271 HydrophobicContact CG2-CB 3.84Å; T264-E271 HydrophobicContact CG2-CG 4.05Å; T264-H272 CarbonylContact C-O 3.49Å; T264-H272 WeakPolarHBondContact CA-O 3.33Å
265V96.9Very high96Very high13 Ų1357 Ų578%0.07932%0.324CS..EExtended strand (participates in β ladder)trans-127.6132177.2-176.50000109.4I263 H272 L346 L391 Y403 L405I263-V265 HydrophobicContact CG1-CG2 4.5Å; I263-V265 HydrophobicContact CG2-CG2 4.18Å; V265-H272 PolarHBondContact N-O 3.06Å; V265-H272 PolarHBondContact O-N 2.87Å; V265-L346 HydrophobicContact CG2-CD1 4.08Å; V265-L391 HydrophobicContact CB-CD1 4.16Å; V265-L391 HydrophobicContact CG1-CD1 4.38Å; V265-L391 HydrophobicContact CG1-CD2 3.89Å; V265-Y403 HydrophobicContact CG1-CE1 4.26Å; V265-L405 HydrophobicContact CG2-CD2 3.74Å
266T94.4Very high96Very high94 Ų9453.5 Ų53.558%0.57731%0.311SS*.EExtended strand (participates in β ladder)trans-87.3119.7176.2-55.20000110.1S270T266-S270 WeakPolarHBondContact CA-O 3.26Å
267A88.3Confident96Very high16 Ų1652.6 Ų52.613%0.13231%0.307CS..EExtended strand (participates in β ladder)trans-139.1144.5173.100000110.3G269 S270 L391A267-G269 PolarHBondContact O-N 3.42Å; A267-S270 PolarHBondContact N-O 2.87Å; A267-S270 PolarHBondContact O-N 2.76Å; A267-L391 HydrophobicContact CB-CD2 3.52Å; A267-L391 HydrophobicContact CB-CG 4.02Å
268T81.8Confident96Very high123 Ų12353.6 Ų53.676%0.75531%0.313SS*.THydrogen-bonded Turntrans53.230.3179.861.40000114.5S270T268-S270 VanDerWaalsContact C-N 3.28Å; T268-S270 PolarHBondContact O-N 3.43Å
269G87.8Confident95.9Very high76 Ų7651.3 Ų51.378%0.78430%0.302SS*.THydrogen-bonded Turntrans76.67.5-179.100000115.3A267A267-G269 PolarHBondContact O-N 3.42Å
270S92.3Very high95.7Very high61 Ų6150.4 Ų50.443%0.42730%0.297SS..EExtended strand (participates in β ladder)trans-123.4150.3176.9-610000111.2T266 A267 T268 H272T266-S270 WeakPolarHBondContact CA-O 3.26Å; A267-S270 PolarHBondContact N-O 2.87Å; A267-S270 PolarHBondContact O-N 2.76Å; T268-S270 VanDerWaalsContact C-N 3.28Å; T268-S270 PolarHBondContact O-N 3.43Å; S270-H272 PolarHBondContact O-CD2 2.98Å
271E96.8Very high95.5Very high150 Ų15046.5 Ų46.570%0.70128%0.276SS*.EExtended strand (participates in β ladder)trans-83.2133171.7-70.2-173162.600110.4T264T264-E271 HydrophobicContact CG2-CB 3.84Å; T264-E271 HydrophobicContact CG2-CG 4.05Å
272H97.9Very high95.2Very high12 Ų1246.6 Ų46.66%0.05628%0.278CS..EExtended strand (participates in β ladder)trans-124.6139.7178.6-66.1-73.1000109.8T264 V265 S270 A387 L391T264-H272 CarbonylContact C-O 3.49Å; T264-H272 WeakPolarHBondContact CA-O 3.33Å; V265-H272 PolarHBondContact N-O 3.06Å; V265-H272 PolarHBondContact O-N 2.87Å; S270-H272 PolarHBondContact O-CD2 2.98Å; H272-A387 HydrophobicContact CB-CB 3.75Å; H272-L391 HydrophobicContact CB-CD1 3.85Å
273V98.4Very high95Very high62 Ų6247.4 Ų47.438%0.37628%0.279SS..EExtended strand (participates in β ladder)trans-107.8120.8176-178.50000108.6M258 I263M258-V273 HydrophobicContact CE-CG1 4.2Å; I263-V273 WeakPolarHBondContact O-CA 3.37Å
274L98.8Very high95Very high0 Ų045.6 Ų45.60%027%0.27CS..EExtended strand (participates in β ladder)trans-131.5172.2172.5-70.4-179.3000109.5S262 I263 L346 N351 R384 A387 M388 L391 L392S262-L274 CarbonylContact C-O 3.58Å; S262-L274 VanDerWaalsContact CA-O 3.31Å; S262-L274 WeakPolarHBondContact CA-O 3.12Å; I263-L274 PolarHBondContact N-O 3.42Å; I263-L274 PolarHBondContact O-N 2.94Å; L274-L346 HydrophobicContact CB-CD1 4.2Å; L274-L346 HydrophobicContact CB-CD2 4.48Å; L274-L346 HydrophobicContact CD1-CD1 3.97Å; L274-N351 WeakPolarHBondContact CB-OD1 3.46Å; L274-N351 HydrophobicContact CD2-CB 4.17Å; L274-N351 WeakPolarHBondContact CD2-OD1 3.45Å; L274-R384 HydrophobicContact CD2-CG 4.16Å; L274-A387 HydrophobicContact CD1-CB 4.45Å; L274-A387 HydrophobicContact CD2-CB 3.66Å; L274-A387 HydrophobicContact CG-CB 3.93Å; L274-M388 HydrophobicContact CD2-CG 3.94Å; L274-L391 HydrophobicContact CD1-CB 4.09Å; L274-L391 HydrophobicContact CD1-CD1 3.61Å; L274-L391 HydrophobicContact CD1-CG 4.49Å; L274-L391 HydrophobicContact CG-CD1 4.29Å; L274-L392 HydrophobicContact CD1-CD1 4.21Å; L274-L392 HydrophobicContact CD1-CD2 4.35Å; L274-L392 HydrophobicContact CD1-CG 4.19Å
275N98.9Very high95Very high0 Ų042 Ų420%025%0.248CC..EExtended strand (participates in β ladder)trans-112.6152.6-178.4-65.576000112W257 R261 P347 L350 N351 L354 R384W257-N275 PolarHBondContact O-ND2 2.71Å; R261-N275 CarbonylContact O-C 3.47Å; R261-N275 WeakPolarHBondContact O-CA 3.21Å; R261-N275 WeakPolarHBondContact O-CB 3.38Å; R261-N275 PolarHBondContact O-ND2 2.81Å; N275-P347 WeakPolarHBondContact O-CD 3.41Å; N275-L350 HydrophobicContact CB-CD2 3.88Å; N275-L350 HydrophobicContact CB-CG 4.22Å; N275-N351 PolarHBondContact N-OD1 2.85Å; N275-N351 PolarHBondContact O-ND2 2.81Å; N275-L354 HydrophobicContact CB-CD1 3.51Å; N275-L354 WeakPolarHBondContact OD1-CD1 3.47Å; N275-R384 PolarHBondContact OD1-NH1 2.93Å; N275-R384 PolarHBondContact OD1-NH2 2.97Å
276R98.6Very high95.1Very high46 Ų4641.4 Ų41.417%0.17424%0.244CC..  trans-136.2153.3174.665.1-172.3-167.3172.5-6.4110R261 N278 S343 I345 L346R261-R276 WeakPolarHBondContact CB-O 3.32Å; R261-R276 PolarHBondContact O-N 2.73Å; R276-N278 HydrophobicContact CG-CB 4.33Å; R276-S343 WeakPolarHBondContact CD-O 3.32Å; R276-S343 VanDerWaalsContact CZ-O 3.22Å; R276-S343 PolarHBondContact NE-O 3.1Å; R276-S343 PolarHBondContact NH1-O 3.36Å; R276-I345 VanDerWaalsContact CB-O 3.3Å; R276-I345 WeakPolarHBondContact CB-O 3.48Å; R276-L346 HydrophobicContact CB-CD2 4.2Å
277F98.7Very high95.2Very high1 Ų137.4 Ų37.40%0.00422%0.219CC..  trans-71.7130.3167.2-60.1-67.7000108.7P223 W257 A313 E316 T342 S343 P347 L350P223-F277 HydrophobicContact CG-CZ 4.34Å; W257-F277 AromaticContact CH2-CD1 3.97Å; W257-F277 HydrophobicContact CH2-CD1 3.97Å; W257-F277 AromaticContact CH2-CE1 3.75Å; W257-F277 HydrophobicContact CH2-CE1 3.75Å; W257-F277 AromaticContact CZ3-CD1 3.97Å; W257-F277 HydrophobicContact CZ3-CD1 3.97Å; W257-F277 AromaticContact CZ3-CE1 3.95Å; W257-F277 HydrophobicContact CZ3-CE1 3.95Å; F277-A313 HydrophobicContact CB-CB 4.2Å; F277-A313 WeakPolarHBondContact CB-O 3.48Å; F277-E316 HydrophobicContact CB-CB 4.41Å; F277-E316 HydrophobicContact CD1-CB 4.19Å; F277-E316 HydrophobicContact CD1-CG 3.81Å; F277-E316 WeakPolarHBondContact CE1-O 3.42Å; F277-T342 HydrophobicContact CB-CG2 4.3Å; F277-S343 WeakPolarHBondContact O-CA 3.23Å; F277-P347 HydrophobicContact CD2-CG 3.75Å; F277-P347 HydrophobicContact CE2-CB 4.2Å; F277-P347 HydrophobicContact CE2-CG 3.89Å; F277-L350 HydrophobicContact CD1-CD2 4.09Å; F277-L350 HydrophobicContact CD2-CD2 4.28Å; F277-L350 HydrophobicContact CE1-CD1 3.89Å; F277-L350 HydrophobicContact CE1-CD2 3.93Å; F277-L350 HydrophobicContact CE1-CG 4.33Å; F277-L350 HydrophobicContact CE2-CB 3.93Å; F277-L350 HydrophobicContact CE2-CD2 4.1Å; F277-L350 HydrophobicContact CE2-CG 4.48Å; F277-L350 HydrophobicContact CG-CD2 4.28Å; F277-L350 HydrophobicContact CZ-CB 3.78Å; F277-L350 HydrophobicContact CZ-CD1 3.91Å; F277-L350 HydrophobicContact CZ-CD2 3.93Å; F277-L350 HydrophobicContact CZ-CG 4.07Å
278N97.8Very high95.6Very high22 Ų2237 Ų3712%0.11822%0.215CC..  trans-158.3113-175-178.147.8000110.4R261 R276 E316R261-N278 WeakPolarHBondContact CD-O 3.36Å; R261-N278 PolarHBondContact NE-O 3.2Å; R261-N278 PolarHBondContact NH1-O 3.36Å; R261-N278 VanDerWaalsContact NH1-O 3.16Å; R261-N278 PolarHBondContact NH2-O 2.86Å; R276-N278 HydrophobicContact CG-CB 4.33Å; N278-E316 PolarHBondContact N-OE2 2.9Å; N278-E316 VanDerWaalsContact N-OE2 3.14Å
279V97.3Very high96.4Very high0 Ų032.5 Ų32.50%019%0.185CC..  trans-118112.9-175.3-178.30000109.8R219 R220 A281 M309 K312 A313 E316R219-V279 HydrophobicContact CB-CG1 4.21Å; R220-V279 HydrophobicContact CB-CB 4.49Å; R220-V279 HydrophobicContact CB-CG1 4.08Å; R220-V279 HydrophobicContact CB-CG2 3.56Å; V279-A281 VanDerWaalsContact C-N 3.3Å; V279-A281 HydrophobicContact CG1-CB 4.34Å; V279-A281 PolarHBondContact O-N 2.89Å; V279-M309 WeakPolarHBondContact O-CB 3.23Å; V279-M309 VanDerWaalsContact O-CG 3.31Å; V279-M309 WeakPolarHBondContact O-CG 3.3Å; V279-K312 HydrophobicContact CB-CB 3.73Å; V279-K312 HydrophobicContact CG1-CB 3.75Å; V279-K312 HydrophobicContact CG1-CD 3.91Å; V279-K312 HydrophobicContact CG1-CG 4.47Å; V279-K312 HydrophobicContact CG2-CB 4.1Å; V279-A313 HydrophobicContact CG2-CB 4.43Å; V279-E316 HydrophobicContact CG2-CB 3.98Å; V279-E316 HydrophobicContact CG2-CG 4.38Å
280E94Very high96.8Very high117 Ų11729.2 Ų29.255%0.54715%0.15SC..  trans-84.868.1-178.4-66.1-175.2159.900111.1L22 P23L22-E280 HydrophobicContact CD2-CB 4.1Å; P23-E280 WeakPolarHBondContact CD-O 3.43Å; P23-E280 WeakPolarHBondContact CG-O 3.23Å
281A94.5Very high97Very high0 Ų029.2 Ų29.20%015%0.145CC..  trans-145.7120.3173.400000110.9P23 R219 V279 K312P23-A281 WeakPolarHBondContact O-CA 3.33Å; R219-A281 HydrophobicContact CB-CB 4.48Å; V279-A281 VanDerWaalsContact C-N 3.3Å; V279-A281 HydrophobicContact CG1-CB 4.34Å; V279-A281 PolarHBondContact O-N 2.89Å; A281-K312 HydrophobicContact CB-CD 4Å; A281-K312 WeakPolarHBondContact O-CE 3.1Å; A281-K312 PolarHBondContact O-NZ 3.16Å
282D90.6Very high97Very high20 Ų2022 Ų2211%0.10711%0.111CC..  trans-107.818.3-162.775-27.6000114.9L22 Q305 Y308L22-D282 HydrophobicContact CB-CB 4.01Å; L22-D282 HydrophobicContact CD1-CB 3.79Å; D282-Q305 HydrophobicContact CB-CB 4.09Å; D282-Q305 HydrophobicContact CB-CG 3.95Å; D282-Q305 PolarHBondContact OD2-NE2 3.37Å; D282-Y308 VanDerWaalsContact O-CD2 3.23Å; D282-Y308 WeakPolarHBondContact O-CD2 3.34Å
283L95.7Very high97Very high60 Ų6023.6 Ų23.631%0.31412%0.12SC..SBendtrans-104.6158.5168.7-58.6-179.2000110.4P24 P25 K312P24-L283 HydrophobicContact CB-CD1 3.87Å; P25-L283 HydrophobicContact CG-CB 4.31Å; L283-K312 WeakPolarHBondContact O-CE 3.47Å; L283-K312 PolarHBondContact O-NZ 3.47Å
284P97.4Very high96.9Very high9 Ų925.4 Ų25.46%0.05812%0.124CC..  trans-50151.7173.8-2734.5000113.5P286 Y289 D292 L293 Y308P284-P286 WeakPolarHBondContact O-CD 3.49Å; P284-Y289 HydrophobicContact CB-CD2 3.67Å; P284-Y289 HydrophobicContact CB-CE2 3.92Å; P284-Y289 HydrophobicContact CB-CG 4.25Å; P284-Y289 HydrophobicContact CG-CD2 4.23Å; P284-Y289 HydrophobicContact CG-CE2 3.98Å; P284-D292 HydrophobicContact CB-CB 3.78Å; P284-L293 HydrophobicContact CG-CD2 3.62Å; P284-L293 HydrophobicContact CG-CG 3.99Å; P284-Y308 HydrophobicContact CG-CE1 4.09Å; P284-Y308 HydrophobicContact CG-CE2 4Å
285R98.3Very high96.9Very high1 Ų127.2 Ų27.20%0.00413%0.133CC..  trans-60122.2167.7-73.2177.5-65154.71.5109E287 S288 Y289 D292 K312 E530R285-E287 PolarHBondContact O-N 3Å; R285-S288 PolarHBondContact NH1-OG 3.26Å; R285-S288 CarbonylContact O-C 3.51Å; R285-S288 VanDerWaalsContact O-C 3.25Å; R285-S288 PolarHBondContact O-N 3.19Å; R285-S288 VanDerWaalsContact O-N 3.16Å; R285-Y289 WeakPolarHBondContact O-CA 3.49Å; R285-Y289 PolarHBondContact O-N 3.49Å; R285-D292 WeakPolarHBondContact CB-OD2 3.43Å; R285-D292 WeakPolarHBondContact CG-OD2 3.47Å; R285-D292 IonicContact CZ-OD1 3.85Å; R285-D292 VanDerWaalsContact CZ-OD1 3.29Å; R285-D292 PolarHBondContact N-OD2 3.16Å; R285-D292 IonicContact NE-OD1 2.73Å; R285-D292 PolarHBondContact NE-OD1 3.31Å; R285-D292 VanDerWaalsContact NE-OD1 3.08Å; R285-D292 IonicContact NE-OD2 2.81Å; R285-D292 PolarHBondContact NE-OD2 3.28Å; R285-D292 IonicContact NH2-OD1 3.16Å; R285-D292 PolarHBondContact NH2-OD1 3.24Å; R285-K312 HydrophobicContact CG-CG 3.73Å; R285-E530 IonicContact CZ-OE1 2.61Å; R285-E530 IonicContact CZ-OE2 3.43Å; R285-E530 IonicContact NH1-OE2 3.49Å; R285-E530 PolarHBondContact NH1-OE2 2.82Å; R285-E530 VanDerWaalsContact NH2-CD 3.32Å; R285-E530 IonicContact NH2-OE1 2.84Å; R285-E530 PolarHBondContact NH2-OE1 2.89Å; R285-E530 IonicContact NH2-OE2 3.33Å; R285-E530 PolarHBondContact NH2-OE2 3.09Å
286P98.1Very high96.8Very high0 Ų027.3 Ų27.30%014%0.135CC..G310 helixtrans-61.2-29.6-178.4-26.336.9000114P25 Y31 C32 L37 Q41 V53 P284P25-P286 HydrophobicContact CB-CG 4.07Å; P25-P286 HydrophobicContact CG-CG 4.18Å; Y31-P286 WeakPolarHBondContact O-CB 3.44Å; C32-P286 HydrophobicContact CB-CG 4.35Å; L37-P286 HydrophobicContact CD1-CB 4.47Å; L37-P286 HydrophobicContact CD2-CB 4.17Å; L37-P286 HydrophobicContact CD2-CG 4.47Å; Q41-P286 PolarHBondContact NE2-O 2.86Å; V53-P286 HydrophobicContact CG1-CB 3.9Å; V53-P286 WeakPolarHBondContact CG1-O 3.46Å; P284-P286 WeakPolarHBondContact O-CD 3.49Å
287E97.6Very high96.7Very high9 Ų932.2 Ų32.24%0.04216%0.159CC..G310 helixtrans-84.1-5.5179.979.4-73.8-176.400115.3D49 K50 V53 Y216 R220 R285D49-E287 WeakPolarHBondContact CB-O 3.43Å; K50-E287 HydrophobicContact CB-CB 4.21Å; K50-E287 HydrophobicContact CG-CB 4.23Å; K50-E287 PolarHBondContact N-O 3.25Å; V53-E287 HydrophobicContact CG2-CB 4.16Å; Y216-E287 HydrophobicContact CD2-CB 4.43Å; Y216-E287 HydrophobicContact CE2-CB 4.01Å; Y216-E287 HydrophobicContact CE2-CG 4.41Å; R220-E287 IonicContact CZ-OE1 3.37Å; R220-E287 IonicContact NH2-OE1 3.81Å; R220-E287 PolarHBondContact NH2-OE1 2.79Å; R220-E287 IonicContact NH2-OE2 3.63Å; R220-E287 PolarHBondContact NH2-OE2 3.44Å; R285-E287 PolarHBondContact O-N 3Å
288S97.4Very high96.6Very high8 Ų835.9 Ų35.96%0.05620%0.197CC..G310 helixtrans-143.642.5176.4-59.90000109.4R285 D292 E530R285-S288 PolarHBondContact NH1-OG 3.26Å; R285-S288 CarbonylContact O-C 3.51Å; R285-S288 VanDerWaalsContact O-C 3.25Å; R285-S288 PolarHBondContact O-N 3.19Å; R285-S288 VanDerWaalsContact O-N 3.16Å; S288-D292 WeakPolarHBondContact O-CB 3.5Å; S288-D292 PolarHBondContact O-N 2.75Å; S288-E530 PolarHBondContact OG-OE2 2.84Å
289Y97.8Very high96.5Very high28 Ų2836.6 Ų36.611%0.1120%0.201CC..Hα-helixtrans-66.7-47.3-163.7-174-90.1000112.6L37 H38 Q41 D49 P284 R285 L293L37-Y289 HydrophobicContact CD2-CD2 3.88Å; L37-Y289 HydrophobicContact CD2-CE2 3.85Å; L37-Y289 HydrophobicContact CG-CD2 4.1Å; L37-Y289 HydrophobicContact CG-CE2 4.13Å; H38-Y289 AromaticContact ND1-CE1 3.95Å; H38-Y289 PolarHBondContact ND1-OH 2.87Å; Q41-Y289 HydrophobicContact CB-CD1 3.47Å; Q41-Y289 VanDerWaalsContact CB-CD1 3.47Å; Q41-Y289 HydrophobicContact CB-CE1 4.23Å; Q41-Y289 HydrophobicContact CB-CG 3.99Å; Q41-Y289 HydrophobicContact CG-CD1 3.89Å; Q41-Y289 HydrophobicContact CG-CG 3.9Å; D49-Y289 PolarHBondContact OD2-N 3.32Å; P284-Y289 HydrophobicContact CB-CD2 3.67Å; P284-Y289 HydrophobicContact CB-CE2 3.92Å; P284-Y289 HydrophobicContact CB-CG 4.25Å; P284-Y289 HydrophobicContact CG-CD2 4.23Å; P284-Y289 HydrophobicContact CG-CE2 3.98Å; R285-Y289 WeakPolarHBondContact O-CA 3.49Å; R285-Y289 PolarHBondContact O-N 3.49Å; Y289-L293 HydrophobicContact CD1-CD1 3.73Å; Y289-L293 HydrophobicContact CD1-CG 4.26Å; Y289-L293 HydrophobicContact CE1-CD1 3.28Å; Y289-L293 HydrophobicContact CE1-CG 4.04Å; Y289-L293 WeakPolarHBondContact O-CG 3.46Å; Y289-L293 PolarHBondContact O-N 3.39Å
290T96.4Very high96.4Very high8 Ų839.2 Ų39.25%0.04922%0.219CC..Hα-helixtrans-68.7-42.2179.258.20000111.6Q41 K44 D49 D292 L293 E294Q41-T290 VanDerWaalsContact C-CG2 3.48Å; Q41-T290 HydrophobicContact CB-CG2 3.95Å; Q41-T290 WeakPolarHBondContact O-CG2 3.46Å; K44-T290 HydrophobicContact CG-CG2 4.39Å; D49-T290 PolarHBondContact OD1-OG1 2.9Å; D49-T290 WeakPolarHBondContact OD2-CB 3.45Å; D49-T290 PolarHBondContact OD2-N 2.92Å; D49-T290 PolarHBondContact OD2-OG1 3.39Å; T290-D292 VanDerWaalsContact C-N 3.34Å; T290-D292 PolarHBondContact O-N 3.32Å; T290-L293 PolarHBondContact O-N 3.07Å; T290-E294 WeakPolarHBondContact O-CB 3.35Å; T290-E294 VanDerWaalsContact O-CG 3.3Å; T290-E294 WeakPolarHBondContact O-CG 3.27Å; T290-E294 PolarHBondContact O-N 3.37Å
291D95.9Very high96.4Very high60 Ų6037.9 Ų37.932%0.32122%0.216SC..Hα-helixtrans-58.5-46.5175.9-64.8-35.4000111.3L295D291-L295 VanDerWaalsContact O-CB 3.23Å; D291-L295 WeakPolarHBondContact O-CB 3.38Å; D291-L295 PolarHBondContact O-N 3.48Å
292D97.9Very high96.4Very high0 Ų043 Ų430%024%0.239CC..Hα-helixtrans-62.8-44.6177-82.912.6000111.6P284 R285 S288 T290 A296 Y308 L311P284-D292 HydrophobicContact CB-CB 3.78Å; R285-D292 WeakPolarHBondContact CB-OD2 3.43Å; R285-D292 WeakPolarHBondContact CG-OD2 3.47Å; R285-D292 IonicContact CZ-OD1 3.85Å; R285-D292 VanDerWaalsContact CZ-OD1 3.29Å; R285-D292 PolarHBondContact N-OD2 3.16Å; R285-D292 IonicContact NE-OD1 2.73Å; R285-D292 PolarHBondContact NE-OD1 3.31Å; R285-D292 VanDerWaalsContact NE-OD1 3.08Å; R285-D292 IonicContact NE-OD2 2.81Å; R285-D292 PolarHBondContact NE-OD2 3.28Å; R285-D292 IonicContact NH2-OD1 3.16Å; R285-D292 PolarHBondContact NH2-OD1 3.24Å; S288-D292 WeakPolarHBondContact O-CB 3.5Å; S288-D292 PolarHBondContact O-N 2.75Å; T290-D292 VanDerWaalsContact C-N 3.34Å; T290-D292 PolarHBondContact O-N 3.32Å; D292-A296 WeakPolarHBondContact O-CB 3.48Å; D292-A296 PolarHBondContact O-N 2.81Å; D292-A296 VanDerWaalsContact O-N 3.09Å; D292-Y308 HydrophobicContact CB-CD1 4.28Å; D292-Y308 HydrophobicContact CB-CE1 4.03Å; D292-Y308 WeakPolarHBondContact O-CE1 3.32Å; D292-L311 HydrophobicContact CB-CD1 4.49Å; D292-L311 WeakPolarHBondContact OD1-CD1 3.38Å
293L96.8Very high96.6Very high45 Ų4545.9 Ų45.924%0.23626%0.255CS..Hα-helixtrans-61.5-48.7178.3-78.5-176000112.1E42 P284 Y289 T290 A296 E297 Y308E42-L293 HydrophobicContact CG-CD1 4.4Å; P284-L293 HydrophobicContact CG-CD2 3.62Å; P284-L293 HydrophobicContact CG-CG 3.99Å; Y289-L293 HydrophobicContact CD1-CD1 3.73Å; Y289-L293 HydrophobicContact CD1-CG 4.26Å; Y289-L293 HydrophobicContact CE1-CD1 3.28Å; Y289-L293 HydrophobicContact CE1-CG 4.04Å; Y289-L293 WeakPolarHBondContact O-CG 3.46Å; Y289-L293 PolarHBondContact O-N 3.39Å; T290-L293 PolarHBondContact O-N 3.07Å; L293-A296 PolarHBondContact O-N 2.67Å; L293-E297 PolarHBondContact O-N 3.22Å; L293-Y308 WeakPolarHBondContact CD2-OH 3.31Å
294E97.1Very high96.6Very high99 Ų9947.2 Ų47.246%0.46326%0.255SS..Hα-helixtrans-63.3-42.9-179.8-72.6176.8-175.300110.8K44 T290 A296 E297K44-E294 WeakPolarHBondContact CE-OE1 3.44Å; K44-E294 IonicContact NZ-OE1 3.93Å; K44-E294 PolarHBondContact NZ-OE1 3.43Å; K44-E294 IonicContact NZ-OE2 2.85Å; T290-E294 WeakPolarHBondContact O-CB 3.35Å; T290-E294 VanDerWaalsContact O-CG 3.3Å; T290-E294 WeakPolarHBondContact O-CG 3.27Å; T290-E294 PolarHBondContact O-N 3.37Å; E294-A296 PolarHBondContact O-N 3.44Å; E294-E297 WeakPolarHBondContact O-CB 3.29Å; E294-E297 PolarHBondContact O-N 3.35Å; E294-E297 VanDerWaalsContact O-N 3.17Å
295L97.1Very high96.6Very high38 Ų3850.2 Ų50.220%0.19927%0.269CS..Hα-helixtrans-61.5-35.5177-172.568.4000112.3D291 E297 L307 L311 L337 R338D291-L295 VanDerWaalsContact O-CB 3.23Å; D291-L295 WeakPolarHBondContact O-CB 3.38Å; D291-L295 PolarHBondContact O-N 3.48Å; L295-E297 VanDerWaalsContact C-N 3.35Å; L295-L307 HydrophobicContact CD2-CD1 4.29Å; L295-L307 HydrophobicContact CD2-CD2 4.13Å; L295-L307 HydrophobicContact CG-CD2 4.09Å; L295-L311 HydrophobicContact CD2-CD1 4.05Å; L295-L311 HydrophobicContact CD2-CD2 4.06Å; L295-L337 HydrophobicContact CD1-CB 4.41Å; L295-L337 HydrophobicContact CD1-CD2 4.5Å; L295-L337 HydrophobicContact CD1-CG 4.38Å; L295-L337 HydrophobicContact CD2-CB 4.48Å; L295-L337 HydrophobicContact CD2-CD2 3.99Å; L295-L337 HydrophobicContact CD2-CG 3.69Å; L295-R338 HydrophobicContact CD1-CB 3.86Å; L295-R338 HydrophobicContact CD1-CG 4.49Å; L295-R338 HydrophobicContact CG-CB 4.32Å; L295-R338 PolarHBondContact O-NH1 2.83Å
296A97.2Very high96.5Very high3 Ų352.7 Ų52.73%0.02528%0.28CS..THydrogen-bonded Turntrans-83.2-4.7-18000000114.7D292 L293 E294 G298 L299 R304 L307 Y308D292-A296 WeakPolarHBondContact O-CB 3.48Å; D292-A296 PolarHBondContact O-N 2.81Å; D292-A296 VanDerWaalsContact O-N 3.09Å; L293-A296 PolarHBondContact O-N 2.67Å; E294-A296 PolarHBondContact O-N 3.44Å; A296-G298 PolarHBondContact O-N 2.76Å; A296-L299 HydrophobicContact CB-CD1 4.39Å; A296-L299 WeakPolarHBondContact O-CB 3.5Å; A296-L299 WeakPolarHBondContact O-CG 3.25Å; A296-L299 PolarHBondContact O-N 3.08Å; A296-L299 VanDerWaalsContact O-N 3.1Å; A296-R304 HydrophobicContact CB-CG 3.86Å; A296-L307 HydrophobicContact CB-CD2 4.1Å; A296-Y308 HydrophobicContact CB-CE1 3.68Å; A296-Y308 WeakPolarHBondContact CB-OH 3.42Å
297E96.8Very high96.4Very high149 Ų14952.7 Ų52.770%0.69628%0.28SS*.THydrogen-bonded Turntrans-57.8132.3-175.4-168179.6-176.200111.6L293 E294 L295 L299 R338L293-E297 PolarHBondContact O-N 3.22Å; E294-E297 WeakPolarHBondContact O-CB 3.29Å; E294-E297 PolarHBondContact O-N 3.35Å; E294-E297 VanDerWaalsContact O-N 3.17Å; L295-E297 VanDerWaalsContact C-N 3.35Å; E297-L299 VanDerWaalsContact C-N 3.27Å; E297-L299 PolarHBondContact O-N 3.39Å; E297-R338 VanDerWaalsContact O-CZ 3.24Å; E297-R338 PolarHBondContact O-NH1 3.41Å; E297-R338 PolarHBondContact O-NH2 3.15Å
298G96.3Very high96.5Very high77 Ų7752.6 Ų52.679%0.79428%0.28SS*.THydrogen-bonded Turntrans75.72.9-179.300000115.7A296A296-G298 PolarHBondContact O-N 2.76Å
299L96.3Very high96.5Very high37 Ų3753.4 Ų53.419%0.19428%0.283CS..  trans-76153.5168.7-65.9-179.1000111.6A296 E297 L303 R304 L307A296-L299 HydrophobicContact CB-CD1 4.39Å; A296-L299 WeakPolarHBondContact O-CB 3.5Å; A296-L299 WeakPolarHBondContact O-CG 3.25Å; A296-L299 PolarHBondContact O-N 3.08Å; A296-L299 VanDerWaalsContact O-N 3.1Å; E297-L299 VanDerWaalsContact C-N 3.27Å; E297-L299 PolarHBondContact O-N 3.39Å; L299-L303 HydrophobicContact CB-CB 4.14Å; L299-L303 HydrophobicContact CD1-CB 4.41Å; L299-L303 HydrophobicContact CD2-CB 4.25Å; L299-L303 HydrophobicContact CD2-CD1 4.33Å; L299-R304 HydrophobicContact CB-CB 4.18Å; L299-L307 HydrophobicContact CD1-CB 4.36Å; L299-L307 HydrophobicContact CD1-CD2 3.67Å
300S96Very high96.5Very high55 Ų5552.1 Ų52.139%0.38528%0.278SS..  trans-66.2160.5165.876.50000110.6E302 L303 R304S300-E302 VanDerWaalsContact C-N 3.26Å; S300-E302 PolarHBondContact O-N 3.38Å; S300-E302 PolarHBondContact OG-OE2 3.32Å; S300-L303 PolarHBondContact O-N 3.43Å; S300-L303 PolarHBondContact OG-N 2.83Å; S300-R304 VanDerWaalsContact O-CB 3.29Å; S300-R304 WeakPolarHBondContact O-CB 3.07Å; S300-R304 PolarHBondContact O-N 3.44Å
301D94.3Very high96.6Very high90 Ų9051.7 Ų51.748%0.48128%0.275SS..Hα-helixtrans-54.5-43.1179.2-70.1-12.6000111.8R304 Q305D301-R304 PolarHBondContact O-N 3.25Å; D301-R304 IonicContact OD1-CZ 2.97Å; D301-R304 IonicContact OD1-NH1 3.04Å; D301-R304 PolarHBondContact OD1-NH1 3.23Å; D301-R304 IonicContact OD1-NH2 3.88Å; D301-R304 PolarHBondContact OD1-NH2 2.91Å; D301-Q305 WeakPolarHBondContact O-CB 3.36Å; D301-Q305 VanDerWaalsContact O-CG 3.27Å; D301-Q305 WeakPolarHBondContact O-CG 3.26Å; D301-Q305 PolarHBondContact O-N 3.11Å
302E93.9Very high96.7Very high106 Ų10648.9 Ų48.950%0.49526%0.26SS..Hα-helixtrans-64.6-45.2179.2-64.274.8-161.400112.6K19 S300 R304 Q306K19-E302 IonicContact NZ-OE1 3.92Å; S300-E302 VanDerWaalsContact C-N 3.26Å; S300-E302 PolarHBondContact O-N 3.38Å; S300-E302 PolarHBondContact OG-OE2 3.32Å; E302-R304 VanDerWaalsContact C-N 3.34Å; E302-Q306 WeakPolarHBondContact O-CB 3.22Å; E302-Q306 PolarHBondContact O-N 3.01Å
303L94.6Very high96.8Very high82 Ų8248.9 Ų48.943%0.42926%0.26SS..Hα-helixtrans-69.1-35.5179.4-71.1176.8000111.6L299 S300 L307L299-L303 HydrophobicContact CB-CB 4.14Å; L299-L303 HydrophobicContact CD1-CB 4.41Å; L299-L303 HydrophobicContact CD2-CB 4.25Å; L299-L303 HydrophobicContact CD2-CD1 4.33Å; S300-L303 PolarHBondContact O-N 3.43Å; S300-L303 PolarHBondContact OG-N 2.83Å; L303-L307 VanDerWaalsContact O-CB 3.32Å; L303-L307 WeakPolarHBondContact O-CB 3.2Å; L303-L307 PolarHBondContact O-N 3.44Å
304R96.4Very high96.8Very high87 Ų8746.7 Ų46.733%0.32825%0.249SC..Hα-helixtrans-65.2-48.9175.3176.2171.176.8-140.8-7111.5A296 L299 S300 D301 E302 Q306 L307 Y308A296-R304 HydrophobicContact CB-CG 3.86Å; L299-R304 HydrophobicContact CB-CB 4.18Å; S300-R304 VanDerWaalsContact O-CB 3.29Å; S300-R304 WeakPolarHBondContact O-CB 3.07Å; S300-R304 PolarHBondContact O-N 3.44Å; D301-R304 PolarHBondContact O-N 3.25Å; D301-R304 IonicContact OD1-CZ 2.97Å; D301-R304 IonicContact OD1-NH1 3.04Å; D301-R304 PolarHBondContact OD1-NH1 3.23Å; D301-R304 IonicContact OD1-NH2 3.88Å; D301-R304 PolarHBondContact OD1-NH2 2.91Å; E302-R304 VanDerWaalsContact C-N 3.34Å; R304-Q306 VanDerWaalsContact C-N 3.32Å; R304-Q306 PolarHBondContact O-N 3.4Å; R304-L307 PolarHBondContact O-N 3.27Å; R304-Y308 WeakPolarHBondContact CD-OH 3.4Å; R304-Y308 HydrophobicContact CG-CD2 3.92Å; R304-Y308 HydrophobicContact CG-CE1 4.3Å; R304-Y308 HydrophobicContact CG-CE2 3.27Å; R304-Y308 VanDerWaalsContact CG-CZ 3.47Å; R304-Y308 WeakPolarHBondContact O-CD2 3.4Å; R304-Y308 PolarHBondContact O-N 3.24Å
305Q95.6Very high96.9Very high72 Ų7242.1 Ų42.134%0.33623%0.228SC..Hα-helixtrans-58.8-45.1176-74.3179.9-28.500111.4D282 D301 Y308 M309D282-Q305 HydrophobicContact CB-CB 4.09Å; D282-Q305 HydrophobicContact CB-CG 3.95Å; D282-Q305 PolarHBondContact OD2-NE2 3.37Å; D301-Q305 WeakPolarHBondContact O-CB 3.36Å; D301-Q305 VanDerWaalsContact O-CG 3.27Å; D301-Q305 WeakPolarHBondContact O-CG 3.26Å; D301-Q305 PolarHBondContact O-N 3.11Å; Q305-Y308 PolarHBondContact O-N 2.74Å; Q305-M309 WeakPolarHBondContact O-CG 3.47Å; Q305-M309 PolarHBondContact O-N 2.79Å; Q305-M309 VanDerWaalsContact O-N 3.1Å
306Q96.2Very high97Very high53 Ų5340.3 Ų40.325%0.24822%0.218CC..Hα-helixtrans-61.3-45.7177-173.759.45600111.8E302 R304 Y308 M309 D310 S343E302-Q306 WeakPolarHBondContact O-CB 3.22Å; E302-Q306 PolarHBondContact O-N 3.01Å; R304-Q306 VanDerWaalsContact C-N 3.32Å; R304-Q306 PolarHBondContact O-N 3.4Å; Q306-Y308 PolarHBondContact O-N 3.15Å; Q306-M309 PolarHBondContact O-N 3.29Å; Q306-D310 PolarHBondContact NE2-OD2 2.94Å; Q306-D310 WeakPolarHBondContact O-CB 3.22Å; Q306-D310 PolarHBondContact O-N 2.93Å; Q306-S343 PolarHBondContact NE2-OG 3.23Å
307L97.6Very high97.1Very high0 Ų040.1 Ų40.10%022%0.217CC..Hα-helixtrans-57.6-47.4176.5177.561.6000111.2L295 A296 L299 L303 R304 M309 D310 L311L295-L307 HydrophobicContact CD2-CD1 4.29Å; L295-L307 HydrophobicContact CD2-CD2 4.13Å; L295-L307 HydrophobicContact CG-CD2 4.09Å; A296-L307 HydrophobicContact CB-CD2 4.1Å; L299-L307 HydrophobicContact CD1-CB 4.36Å; L299-L307 HydrophobicContact CD1-CD2 3.67Å; L303-L307 VanDerWaalsContact O-CB 3.32Å; L303-L307 WeakPolarHBondContact O-CB 3.2Å; L303-L307 PolarHBondContact O-N 3.44Å; R304-L307 PolarHBondContact O-N 3.27Å; L307-M309 VanDerWaalsContact C-N 3.33Å; L307-M309 PolarHBondContact O-N 3.47Å; L307-D310 PolarHBondContact O-N 3.22Å; L307-D310 VanDerWaalsContact O-N 3.15Å; L307-L311 HydrophobicContact CD1-CD1 4.03Å; L307-L311 HydrophobicContact CD1-CD2 4.29Å; L307-L311 HydrophobicContact CD1-CG 3.94Å; L307-L311 HydrophobicContact CG-CD1 3.84Å; L307-L311 HydrophobicContact CG-CG 4.23Å; L307-L311 VanDerWaalsContact O-CG 3.26Å; L307-L311 WeakPolarHBondContact O-CG 3.37Å; L307-L311 PolarHBondContact O-N 3.49Å
308Y98.1Very high97.1Very high8 Ų833.2 Ų33.23%0.03119%0.185CC..Hα-helixtrans-62.4-37.3179.2-64.6-30.3000113.7D282 P284 D292 L293 A296 R304 Q305 Q306 L311 K312D282-Y308 VanDerWaalsContact O-CD2 3.23Å; D282-Y308 WeakPolarHBondContact O-CD2 3.34Å; P284-Y308 HydrophobicContact CG-CE1 4.09Å; P284-Y308 HydrophobicContact CG-CE2 4Å; D292-Y308 HydrophobicContact CB-CD1 4.28Å; D292-Y308 HydrophobicContact CB-CE1 4.03Å; D292-Y308 WeakPolarHBondContact O-CE1 3.32Å; L293-Y308 WeakPolarHBondContact CD2-OH 3.31Å; A296-Y308 HydrophobicContact CB-CE1 3.68Å; A296-Y308 WeakPolarHBondContact CB-OH 3.42Å; R304-Y308 WeakPolarHBondContact CD-OH 3.4Å; R304-Y308 HydrophobicContact CG-CD2 3.92Å; R304-Y308 HydrophobicContact CG-CE1 4.3Å; R304-Y308 HydrophobicContact CG-CE2 3.27Å; R304-Y308 VanDerWaalsContact CG-CZ 3.47Å; R304-Y308 WeakPolarHBondContact O-CD2 3.4Å; R304-Y308 PolarHBondContact O-N 3.24Å; Q305-Y308 PolarHBondContact O-N 2.74Å; Q306-Y308 PolarHBondContact O-N 3.15Å; Y308-L311 HydrophobicContact CD1-CD1 4.4Å; Y308-K312 PolarHBondContact O-N 2.93Å; Y308-K312 PolarHBondContact O-NZ 3.21Å
309M98.1Very high97.2Very high25 Ų2529.6 Ų29.612%0.12315%0.148CC..Hα-helixtrans-66.1-43.3173.5-70.4-170.8-68.500111.3L22 V279 Q305 Q306 L307 K312 A313L22-M309 HydrophobicContact CD1-CE 4.18Å; L22-M309 HydrophobicContact CD1-CG 4.42Å; L22-M309 HydrophobicContact CD1-SD 3.42Å; L22-M309 WeakPolarHBondContact CD1-SD 3.15Å; V279-M309 WeakPolarHBondContact O-CB 3.23Å; V279-M309 VanDerWaalsContact O-CG 3.31Å; V279-M309 WeakPolarHBondContact O-CG 3.3Å; Q305-M309 WeakPolarHBondContact O-CG 3.47Å; Q305-M309 PolarHBondContact O-N 2.79Å; Q305-M309 VanDerWaalsContact O-N 3.1Å; Q306-M309 PolarHBondContact O-N 3.29Å; L307-M309 VanDerWaalsContact C-N 3.33Å; L307-M309 PolarHBondContact O-N 3.47Å; M309-K312 PolarHBondContact O-N 3.49Å; M309-A313 WeakPolarHBondContact O-CB 3.36Å; M309-A313 PolarHBondContact O-N 2.99Å
310D98.4Very high97.2Very high0 Ų029.3 Ų29.30%015%0.146CC..Hα-helixtrans-70.5-33.3-178.7-80.6-43000113.4Q306 L307 A313 G314 T340 T342 S343Q306-D310 PolarHBondContact NE2-OD2 2.94Å; Q306-D310 WeakPolarHBondContact O-CB 3.22Å; Q306-D310 PolarHBondContact O-N 2.93Å; L307-D310 PolarHBondContact O-N 3.22Å; L307-D310 VanDerWaalsContact O-N 3.15Å; D310-A313 PolarHBondContact O-N 3.36Å; D310-G314 PolarHBondContact O-N 3.48Å; D310-T340 HydrophobicContact CB-CG2 4.08Å; D310-T340 WeakPolarHBondContact CB-O 3.31Å; D310-T342 PolarHBondContact O-OG1 3.3Å; D310-T342 PolarHBondContact OD1-N 2.86Å; D310-S343 WeakPolarHBondContact OD1-CB 3.39Å; D310-S343 PolarHBondContact OD1-N 3.18Å; D310-S343 PolarHBondContact OD1-OG 3.36Å
311L98.6Very high97.3Very high0 Ų026.7 Ų26.70%013%0.128CC..Hα-helixtrans-64.6-43.7171.4-69.1168.5000110.9D292 L295 L307 Y308 G314 A315 F321 L337D292-L311 HydrophobicContact CB-CD1 4.49Å; D292-L311 WeakPolarHBondContact OD1-CD1 3.38Å; L295-L311 HydrophobicContact CD2-CD1 4.05Å; L295-L311 HydrophobicContact CD2-CD2 4.06Å; L307-L311 HydrophobicContact CD1-CD1 4.03Å; L307-L311 HydrophobicContact CD1-CD2 4.29Å; L307-L311 HydrophobicContact CD1-CG 3.94Å; L307-L311 HydrophobicContact CG-CD1 3.84Å; L307-L311 HydrophobicContact CG-CG 4.23Å; L307-L311 VanDerWaalsContact O-CG 3.26Å; L307-L311 WeakPolarHBondContact O-CG 3.37Å; L307-L311 PolarHBondContact O-N 3.49Å; Y308-L311 HydrophobicContact CD1-CD1 4.4Å; L311-G314 WeakPolarHBondContact O-CA 3.34Å; L311-G314 PolarHBondContact O-N 3.38Å; L311-G314 VanDerWaalsContact O-N 3.17Å; L311-A315 PolarHBondContact O-N 3.27Å; L311-F321 HydrophobicContact CB-CE1 4.31Å; L311-F321 HydrophobicContact CB-CZ 4.14Å; L311-F321 HydrophobicContact CD2-CD1 4.37Å; L311-F321 HydrophobicContact CD2-CE1 3.67Å; L311-F321 HydrophobicContact CD2-CE2 4.18Å; L311-F321 HydrophobicContact CD2-CZ 3.54Å; L311-F321 HydrophobicContact CG-CZ 4.44Å; L311-L337 HydrophobicContact CD2-CD1 3.93Å; L311-L337 HydrophobicContact CD2-CG 4.38Å
312K98.4Very high97.5Very high0 Ų022.4 Ų22.40%011%0.105CC..Hα-helixtrans-66.7-36.7174.3-74.7-179.7-150.270.10113R220 V279 A281 L283 R285 Y308 M309 G314 A315 E316R220-K312 WeakPolarHBondContact CD-O 3.43Å; V279-K312 HydrophobicContact CB-CB 3.73Å; V279-K312 HydrophobicContact CG1-CB 3.75Å; V279-K312 HydrophobicContact CG1-CD 3.91Å; V279-K312 HydrophobicContact CG1-CG 4.47Å; V279-K312 HydrophobicContact CG2-CB 4.1Å; A281-K312 HydrophobicContact CB-CD 4Å; A281-K312 WeakPolarHBondContact O-CE 3.1Å; A281-K312 PolarHBondContact O-NZ 3.16Å; L283-K312 WeakPolarHBondContact O-CE 3.47Å; L283-K312 PolarHBondContact O-NZ 3.47Å; R285-K312 HydrophobicContact CG-CG 3.73Å; Y308-K312 PolarHBondContact O-N 2.93Å; Y308-K312 PolarHBondContact O-NZ 3.21Å; M309-K312 PolarHBondContact O-N 3.49Å; K312-G314 VanDerWaalsContact C-N 3.3Å; K312-A315 PolarHBondContact O-N 3.46Å; K312-E316 WeakPolarHBondContact O-CB 3.38Å; K312-E316 PolarHBondContact O-N 3.08Å
313A98.6Very high97.7Very high0 Ų017.4 Ų17.40%08%0.082CC..Hα-helixtrans-66.5-34.6172.100000111.3F277 V279 M309 D310 E316 S317 T342F277-A313 HydrophobicContact CB-CB 4.2Å; F277-A313 WeakPolarHBondContact CB-O 3.48Å; V279-A313 HydrophobicContact CG2-CB 4.43Å; M309-A313 WeakPolarHBondContact O-CB 3.36Å; M309-A313 PolarHBondContact O-N 2.99Å; D310-A313 PolarHBondContact O-N 3.36Å; A313-E316 WeakPolarHBondContact O-CB 3.26Å; A313-E316 PolarHBondContact O-N 3.33Å; A313-S317 PolarHBondContact O-N 2.93Å; A313-T342 HydrophobicContact CB-CG2 4.06Å
314G98.4Very high97.8Very high0 Ų013.5 Ų13.50%06%0.061CC..Hα-helixtrans-57.9-49.2169.100000111.5D310 L311 K312 E316 S317D310-G314 PolarHBondContact O-N 3.48Å; L311-G314 WeakPolarHBondContact O-CA 3.34Å; L311-G314 PolarHBondContact O-N 3.38Å; L311-G314 VanDerWaalsContact O-N 3.17Å; K312-G314 VanDerWaalsContact C-N 3.3Å; G314-E316 PolarHBondContact O-N 3.27Å; G314-S317 WeakPolarHBondContact O-CB 3.46Å; G314-S317 PolarHBondContact O-N 3.14Å; G314-S317 VanDerWaalsContact O-N 3.13Å; G314-S317 PolarHBondContact O-OG 3.11Å
315A98.4Very high97.9Very high2 Ų29.3 Ų9.32%0.0175%0.046CC..Hα-helixtrans-64.7-35.8173.300000113.5N211 L311 K312 S317 G318 D320N211-A315 PolarHBondContact ND2-O 3.11Å; N211-A315 VanDerWaalsContact ND2-O 3.08Å; L311-A315 PolarHBondContact O-N 3.27Å; K312-A315 PolarHBondContact O-N 3.46Å; A315-S317 PolarHBondContact O-N 3.46Å; A315-G318 PolarHBondContact O-N 3.41Å; A315-G318 VanDerWaalsContact O-N 3.11Å; A315-D320 HydrophobicContact CB-CB 4.24Å
316E98.8Very high97.9Very high0 Ų06 Ų60%03%0.03CC..Hα-helixtrans-63.7-26.4173.4-167.6174.3-114.100112.2R220 S221 Q222 W257 R261 F277 N278 V279 K312 A313 G314 G318R220-E316 WeakPolarHBondContact CA-OE1 3.36Å; R220-E316 HydrophobicContact CB-CB 4.14Å; R220-E316 HydrophobicContact CB-CG 4.27Å; S221-E316 PolarHBondContact N-OE1 3.46Å; Q222-E316 VanDerWaalsContact CA-O 3.26Å; Q222-E316 WeakPolarHBondContact CA-O 3.28Å; W257-E316 HydrophobicContact CH2-CG 4.5Å; R261-E316 IonicContact CZ-OE1 3.09Å; R261-E316 IonicContact CZ-OE2 2.78Å; R261-E316 IonicContact NE-OE1 3.88Å; R261-E316 PolarHBondContact NE-OE1 2.83Å; R261-E316 IonicContact NE-OE2 3.23Å; R261-E316 PolarHBondContact NE-OE2 2.98Å; R261-E316 IonicContact NH2-OE1 3.15Å; R261-E316 PolarHBondContact NH2-OE1 3.43Å; R261-E316 IonicContact NH2-OE2 3.74Å; F277-E316 HydrophobicContact CB-CB 4.41Å; F277-E316 HydrophobicContact CD1-CB 4.19Å; F277-E316 HydrophobicContact CD1-CG 3.81Å; F277-E316 WeakPolarHBondContact CE1-O 3.42Å; N278-E316 PolarHBondContact N-OE2 2.9Å; N278-E316 VanDerWaalsContact N-OE2 3.14Å; V279-E316 HydrophobicContact CG2-CB 3.98Å; V279-E316 HydrophobicContact CG2-CG 4.38Å; K312-E316 WeakPolarHBondContact O-CB 3.38Å; K312-E316 PolarHBondContact O-N 3.08Å; A313-E316 WeakPolarHBondContact O-CB 3.26Å; A313-E316 PolarHBondContact O-N 3.33Å; G314-E316 PolarHBondContact O-N 3.27Å; E316-G318 VanDerWaalsContact C-N 3.25Å; E316-G318 PolarHBondContact O-N 3.42Å
317S98.8Very high97.8Very high0 Ų03.7 Ų3.70%02%0.02CC..THydrogen-bonded Turntrans-74.3-17.3175.381.40000113.7P223 A313 G314 A315 W319 W325P223-S317 VanDerWaalsContact CG-O 3.24Å; P223-S317 WeakPolarHBondContact CG-O 3.39Å; A313-S317 PolarHBondContact O-N 2.93Å; G314-S317 WeakPolarHBondContact O-CB 3.46Å; G314-S317 PolarHBondContact O-N 3.14Å; G314-S317 VanDerWaalsContact O-N 3.13Å; G314-S317 PolarHBondContact O-OG 3.11Å; A315-S317 PolarHBondContact O-N 3.46Å; S317-W319 PolarHBondContact O-N 2.63Å; S317-W319 PolarHBondContact OG-N 2.77Å; S317-W325 WeakPolarHBondContact OG-CZ2 3.49Å
318G98.2Very high97.4Very high3 Ų35 Ų53%0.0313%0.027CC..THydrogen-bonded Turntrans75.8-2.7-167.300000114.1W174 A315 E316 W463W174-G318 WeakPolarHBondContact CZ2-O 3.41Å; A315-G318 PolarHBondContact O-N 3.41Å; A315-G318 VanDerWaalsContact O-N 3.11Å; E316-G318 VanDerWaalsContact C-N 3.25Å; E316-G318 PolarHBondContact O-N 3.42Å; G318-W463 WeakPolarHBondContact O-CZ2 3.24Å; G318-W463 PolarHBondContact O-NE1 3.08Å; G318-W463 VanDerWaalsContact O-NE1 3.16Å
319W98.3Very high96.8Very high1 Ų110.6 Ų10.60%0.0047%0.067CC..  trans-110.860.5178.9-66.244.1000111.4W174 S317 F321 T322 W325 Y415 T454 W463 L472W174-W319 AromaticContact CH2-CD1 3.77Å; W174-W319 AromaticContact CH2-NE1 3.76Å; S317-W319 PolarHBondContact O-N 2.63Å; S317-W319 PolarHBondContact OG-N 2.77Å; W319-F321 WeakPolarHBondContact O-CA 3.45Å; W319-T322 HydrophobicContact CB-CG2 3.86Å; W319-T322 HydrophobicContact CE3-CG2 3.93Å; W319-W325 HydrophobicContact CB-CZ2 4.08Å; W319-W325 PolarHBondContact O-NE1 3.49Å; W319-Y415 HydrophobicContact CZ3-CD1 4.06Å; W319-T454 HydrophobicContact CD2-CG2 4.44Å; W319-T454 HydrophobicContact CE3-CG2 3.62Å; W319-T454 HydrophobicContact CH2-CG2 3.54Å; W319-T454 HydrophobicContact CZ2-CG2 4.35Å; W319-T454 HydrophobicContact CZ3-CG2 3.12Å; W319-W463 VanDerWaalsContact CA-CD1 3.47Å; W319-W463 HydrophobicContact CB-CB 4.09Å; W319-W463 HydrophobicContact CB-CD2 4.06Å; W319-W463 HydrophobicContact CB-CE3 4.44Å; W319-W463 HydrophobicContact CB-CG 3.89Å; W319-W463 AromaticContact CD1-CE3 3.93Å; W319-W463 HydrophobicContact CD2-CB 4.33Å; W319-W463 HydrophobicContact CD2-CD2 4.12Å; W319-W463 AromaticContact CD2-CE3 3.63Å; W319-W463 HydrophobicContact CD2-CE3 3.63Å; W319-W463 HydrophobicContact CD2-CG 4.43Å; W319-W463 HydrophobicContact CD2-CZ3 4.29Å; W319-W463 AromaticContact CE2-CE3 3.83Å; W319-W463 HydrophobicContact CE3-CB 4.03Å; W319-W463 HydrophobicContact CE3-CE3 4.15Å; W319-W463 HydrophobicContact CG-CB 4.38Å; W319-W463 AromaticContact CG-CD2 3.85Å; W319-W463 HydrophobicContact CG-CD2 3.85Å; W319-W463 AromaticContact CG-CE3 3.74Å; W319-W463 HydrophobicContact CG-CE3 3.74Å; W319-W463 HydrophobicContact CG-CG 4.13Å; W319-W463 HydrophobicContact CG-CZ3 4.31Å; W319-W463 AromaticContact NE1-CE3 3.95Å; W319-W463 AromaticContact NE1-CZ3 3.84Å; W319-L472 HydrophobicContact CH2-CD1 3.8Å; W319-L472 HydrophobicContact CH2-CD2 4.37Å; W319-L472 HydrophobicContact CZ2-CD1 3.58Å; W319-L472 HydrophobicContact CZ2-CD2 3.47Å; W319-L472 VanDerWaalsContact CZ2-CD2 3.47Å; W319-L472 HydrophobicContact CZ2-CG 4.17Å
320D96.1Very high96.1Very high31 Ų3113.8 Ų13.817%0.1669%0.088CC..  trans-96.5100.5174.951.8-51.1000110.9A315 Q462A315-D320 HydrophobicContact CB-CB 4.24Å; D320-Q462 WeakPolarHBondContact O-CG 3.23Å; D320-Q462 PolarHBondContact O-NE2 3.29Å
321F97.7Very high95.4Very high1 Ų114.4 Ų14.40%0.0049%0.094CC..SBendcis-124.3169.9-4.8-61.8-75.8000112.7L311 W319 F326 L337 Q461 W463 E530L311-F321 HydrophobicContact CB-CE1 4.31Å; L311-F321 HydrophobicContact CB-CZ 4.14Å; L311-F321 HydrophobicContact CD2-CD1 4.37Å; L311-F321 HydrophobicContact CD2-CE1 3.67Å; L311-F321 HydrophobicContact CD2-CE2 4.18Å; L311-F321 HydrophobicContact CD2-CZ 3.54Å; L311-F321 HydrophobicContact CG-CZ 4.44Å; W319-F321 WeakPolarHBondContact O-CA 3.45Å; F321-F326 HydrophobicContact CB-CE1 4.34Å; F321-F326 HydrophobicContact CB-CZ 4.17Å; F321-L337 HydrophobicContact CB-CD1 3.56Å; F321-L337 HydrophobicContact CD1-CD1 3.76Å; F321-L337 HydrophobicContact CD2-CD1 3.51Å; F321-L337 HydrophobicContact CD2-CD2 4.19Å; F321-L337 HydrophobicContact CE1-CD1 4.35Å; F321-L337 HydrophobicContact CE2-CD1 4.13Å; F321-L337 HydrophobicContact CG-CD1 3.29Å; F321-Q461 HydrophobicContact CB-CG 4.5Å; F321-Q461 WeakPolarHBondContact O-CB 3.14Å; F321-W463 WeakPolarHBondContact O-CB 3.32Å; F321-W463 PolarHBondContact O-N 3.05Å; F321-E530 VanDerWaalsContact CE2-OE1 3.26Å; F321-E530 WeakPolarHBondContact CE2-OE1 3.47Å
322T98.1Very high94.7Very high0 Ų019.8 Ų19.80%012%0.119CC..  trans-151.6148-177.6173.90000109.9W319 R324 W325 F326 W463 D464W319-T322 HydrophobicContact CB-CG2 3.86Å; W319-T322 HydrophobicContact CE3-CG2 3.93Å; T322-R324 HydrophobicContact CG2-CB 3.46Å; T322-R324 VanDerWaalsContact CG2-CB 3.46Å; T322-R324 PolarHBondContact O-N 3.04Å; T322-R324 VanDerWaalsContact O-N 3.09Å; T322-R324 WeakPolarHBondContact OG1-CB 3.37Å; T322-R324 PolarHBondContact OG1-N 3.04Å; T322-R324 VanDerWaalsContact OG1-N 3.15Å; T322-W325 HydrophobicContact CG2-CD2 4.13Å; T322-W325 HydrophobicContact CG2-CG 3.94Å; T322-W325 HydrophobicContact CG2-CZ2 4.4Å; T322-W325 PolarHBondContact O-N 2.97Å; T322-W325 VanDerWaalsContact O-N 3.13Å; T322-F326 WeakPolarHBondContact O-CD1 3.47Å; T322-F326 WeakPolarHBondContact O-CE1 3.23Å; T322-F326 WeakPolarHBondContact O-CZ 3.3Å; T322-W463 WeakPolarHBondContact CB-O 3.11Å; T322-W463 HydrophobicContact CG2-CB 4.32Å; T322-W463 PolarHBondContact OG1-O 2.93Å; T322-D464 PolarHBondContact OG1-OD1 3.21Å
323S97.4Very high94.1Very high0 Ų020.9 Ų20.90%013%0.125CC..G310 helixtrans-58-16.217065.70000114W325 F326 Y415 D464S323-W325 PolarHBondContact O-N 2.98Å; S323-F326 PolarHBondContact O-N 3.26Å; S323-Y415 VanDerWaalsContact C-OH 3.31Å; S323-Y415 PolarHBondContact OG-OH 2.92Å; S323-Y415 VanDerWaalsContact OG-OH 3.1Å; S323-D464 WeakPolarHBondContact CB-OD2 3.41Å; S323-D464 PolarHBondContact N-OD2 3.16Å; S323-D464 VanDerWaalsContact OG-CG 3.25Å; S323-D464 PolarHBondContact OG-OD1 3.04Å; S323-D464 PolarHBondContact OG-OD2 3.08Å
324R97.6Very high93.6Very high0 Ų025.1 Ų25.10%015%0.148CC..G310 helixtrans-51.5-35.4170.2-164.3179.1175.2-161.8-9.5112.4T322 N333 I345 D349 D402 Y415 S417T322-R324 HydrophobicContact CG2-CB 3.46Å; T322-R324 VanDerWaalsContact CG2-CB 3.46Å; T322-R324 PolarHBondContact O-N 3.04Å; T322-R324 VanDerWaalsContact O-N 3.09Å; T322-R324 WeakPolarHBondContact OG1-CB 3.37Å; T322-R324 PolarHBondContact OG1-N 3.04Å; T322-R324 VanDerWaalsContact OG1-N 3.15Å; R324-N333 PolarHBondContact O-ND2 2.67Å; R324-I345 WeakPolarHBondContact O-CD1 3.5Å; R324-D349 IonicContact CZ-OD1 3.53Å; R324-D349 IonicContact CZ-OD2 3.22Å; R324-D349 IonicContact NH1-OD1 3.24Å; R324-D349 IonicContact NH1-OD2 3.46Å; R324-D349 PolarHBondContact NH1-OD2 3.08Å; R324-D349 IonicContact NH2-OD1 3.61Å; R324-D349 PolarHBondContact NH2-OD1 2.95Å; R324-D349 IonicContact NH2-OD2 3.53Å; R324-D349 PolarHBondContact NH2-OD2 3.33Å; R324-D402 WeakPolarHBondContact CG-OD2 3.47Å; R324-D402 IonicContact CZ-OD1 2.64Å; R324-D402 IonicContact CZ-OD2 3.1Å; R324-D402 IonicContact NE-OD1 2.85Å; R324-D402 IonicContact NE-OD2 2.84Å; R324-D402 PolarHBondContact NE-OD2 3.26Å; R324-D402 IonicContact NH2-OD1 3.75Å; R324-D402 PolarHBondContact NH2-OD1 3.17Å; R324-D402 IonicContact NH2-OD2 3.37Å; R324-D402 PolarHBondContact NH2-OD2 3.13Å; R324-Y415 VanDerWaalsContact CA-CZ 3.44Å; R324-Y415 VanDerWaalsContact CA-OH 3.28Å; R324-Y415 WeakPolarHBondContact CA-OH 3.44Å; R324-Y415 HydrophobicContact CB-CD1 4.02Å; R324-Y415 HydrophobicContact CB-CE1 3.55Å; R324-Y415 HydrophobicContact CB-CE2 4.18Å; R324-Y415 HydrophobicContact CG-CD1 4.17Å; R324-Y415 HydrophobicContact CG-CD2 4.11Å; R324-Y415 HydrophobicContact CG-CE1 4.09Å; R324-Y415 HydrophobicContact CG-CE2 4.03Å; R324-Y415 HydrophobicContact CG-CG 4.19Å; R324-Y415 PolarHBondContact N-OH 3.43Å; R324-S417 VanDerWaalsContact CZ-OG 3.22Å; R324-S417 PolarHBondContact NH1-OG 3.39Å; R324-S417 PolarHBondContact NH2-OG 3.26Å
325W98.1Very high93.4Very high0 Ų025.5 Ų25.50%015%0.151CC..G310 helixtrans-96.1-8.2-174.7-46.5137.4000114.5S317 W319 T322 S323 I327 T340 R341 T342 I345 P347S317-W325 WeakPolarHBondContact OG-CZ2 3.49Å; W319-W325 HydrophobicContact CB-CZ2 4.08Å; W319-W325 PolarHBondContact O-NE1 3.49Å; T322-W325 HydrophobicContact CG2-CD2 4.13Å; T322-W325 HydrophobicContact CG2-CG 3.94Å; T322-W325 HydrophobicContact CG2-CZ2 4.4Å; T322-W325 PolarHBondContact O-N 2.97Å; T322-W325 VanDerWaalsContact O-N 3.13Å; S323-W325 PolarHBondContact O-N 2.98Å; W325-I327 PolarHBondContact O-N 2.81Å; W325-T340 HydrophobicContact CB-CG2 3.95Å; W325-T340 WeakPolarHBondContact O-CA 3.47Å; W325-R341 PolarHBondContact O-N 3.21Å; W325-T342 HydrophobicContact CD2-CG2 3.87Å; W325-T342 HydrophobicContact CE3-CG2 4.06Å; W325-T342 HydrophobicContact CG-CG2 4.19Å; W325-T342 HydrophobicContact CZ3-CG2 4.46Å; W325-I345 HydrophobicContact CE3-CB 4.49Å; W325-I345 HydrophobicContact CE3-CD1 3.7Å; W325-I345 HydrophobicContact CE3-CG2 4.39Å; W325-I345 HydrophobicContact CZ3-CB 4.43Å; W325-I345 HydrophobicContact CZ3-CD1 4.38Å; W325-I345 HydrophobicContact CZ3-CG2 3.99Å; W325-P347 HydrophobicContact CH2-CB 4.26Å; W325-P347 HydrophobicContact CH2-CG 4.34Å; W325-P347 HydrophobicContact CZ3-CG 4.39Å
326F96.9Very high93.2Very high3 Ų329.3 Ų29.31%0.01317%0.174CC..BIsolated β-bridgetrans-88.195.6-168.5-58.9-11.9000110.7F321 T322 S323 N333 T336 L337 T340 Q461F321-F326 HydrophobicContact CB-CE1 4.34Å; F321-F326 HydrophobicContact CB-CZ 4.17Å; T322-F326 WeakPolarHBondContact O-CD1 3.47Å; T322-F326 WeakPolarHBondContact O-CE1 3.23Å; T322-F326 WeakPolarHBondContact O-CZ 3.3Å; S323-F326 PolarHBondContact O-N 3.26Å; F326-N333 CarbonylContact O-C 3.56Å; F326-N333 VanDerWaalsContact O-CA 3.24Å; F326-N333 WeakPolarHBondContact O-CA 3.26Å; F326-T336 WeakPolarHBondContact CB-O 3.37Å; F326-T336 WeakPolarHBondContact CD1-O 3.39Å; F326-T336 VanDerWaalsContact CG-C 3.49Å; F326-T336 WeakPolarHBondContact CG-O 3.39Å; F326-L337 HydrophobicContact CE1-CB 4.26Å; F326-L337 HydrophobicContact CE1-CD1 3.71Å; F326-L337 HydrophobicContact CE2-CB 4.46Å; F326-L337 HydrophobicContact CZ-CB 3.9Å; F326-L337 HydrophobicContact CZ-CD1 3.8Å; F326-L337 HydrophobicContact CZ-CG 4.48Å; F326-T340 WeakPolarHBondContact CD1-OG1 3.45Å; F326-T340 VanDerWaalsContact CE1-OG1 3.26Å; F326-T340 WeakPolarHBondContact CE1-OG1 3.41Å; F326-Q461 HydrophobicContact CE2-CG 3.85Å; F326-Q461 HydrophobicContact CZ-CG 3.78Å
327I94.3Very high93.1Very high4 Ų430.4 Ų30.42%0.02118%0.18CC..  trans-103109.4179.5-57.5173.5000108.5W325 Q332 D339 R341 I345 N404 L406W325-I327 PolarHBondContact O-N 2.81Å; I327-Q332 WeakPolarHBondContact CA-O 3.41Å; I327-D339 PolarHBondContact N-O 2.81Å; I327-R341 HydrophobicContact CB-CB 3.99Å; I327-R341 HydrophobicContact CB-CG 4.07Å; I327-R341 HydrophobicContact CD1-CB 3.87Å; I327-R341 HydrophobicContact CG1-CB 4.14Å; I327-I345 HydrophobicContact CD1-CD1 3.74Å; I327-I345 HydrophobicContact CD1-CG1 3.68Å; I327-I345 HydrophobicContact CG1-CD1 4.21Å; I327-N404 WeakPolarHBondContact CD1-ND2 3.34Å; I327-L406 HydrophobicContact CD1-CD1 4.41Å; I327-L406 HydrophobicContact CG2-CD1 4.09Å
328N89.2Confident93Very high28 Ų2834.6 Ų34.615%0.1520%0.196CC..  trans-66.1178.617980.10.7000112T330 G331 Q332 D334N328-T330 PolarHBondContact ND2-OG1 3.07Å; N328-T330 VanDerWaalsContact ND2-OG1 3.09Å; N328-T330 PolarHBondContact O-N 3.07Å; N328-T330 VanDerWaalsContact O-N 3.15Å; N328-T330 WeakPolarHBondContact OD1-CA 3.44Å; N328-T330 PolarHBondContact OD1-N 2.92Å; N328-T330 PolarHBondContact OD1-OG1 3.15Å; N328-G331 PolarHBondContact O-N 2.8Å; N328-G331 PolarHBondContact OD1-N 3.35Å; N328-Q332 PolarHBondContact N-O 2.74Å; N328-Q332 PolarHBondContact OD1-N 3.38Å; N328-Q332 PolarHBondContact OD1-O 2.96Å; N328-D334 VanDerWaalsContact CG-OD1 3.26Å; N328-D334 PolarHBondContact ND2-OD1 3.24Å
329S84.8Confident92.9Very high125 Ų12536.6 Ų36.687%0.87421%0.206SC*.THydrogen-bonded Turntrans-63.7-18.5179.859.70000115.3
330T83.9Confident92.9Very high92 Ų9236.6 Ų36.656%0.56421%0.206SC*.THydrogen-bonded Turntrans-93.41175.467.60000113N328 Q332N328-T330 PolarHBondContact ND2-OG1 3.07Å; N328-T330 VanDerWaalsContact ND2-OG1 3.09Å; N328-T330 PolarHBondContact O-N 3.07Å; N328-T330 VanDerWaalsContact O-N 3.15Å; N328-T330 WeakPolarHBondContact OD1-CA 3.44Å; N328-T330 PolarHBondContact OD1-N 2.92Å; N328-T330 PolarHBondContact OD1-OG1 3.15Å; T330-Q332 PolarHBondContact OG1-OE1 3.46Å
331G82.6Confident92.9Very high12 Ų1237.4 Ų37.412%0.12421%0.207CC..SBendtrans84.410.1-178.500000114.2N328 N404 T407N328-G331 PolarHBondContact O-N 2.8Å; N328-G331 PolarHBondContact OD1-N 3.35Å; G331-N404 PolarHBondContact O-ND2 3.41Å; G331-N404 VanDerWaalsContact O-ND2 3.15Å; G331-T407 WeakPolarHBondContact O-CG2 3.46Å
332Q85.1Confident93Very high113 Ų11337.4 Ų37.453%0.52821%0.207SC..  trans-95.2149.8-179.4-63179-42.700111.9I327 N328 T330 D334I327-Q332 WeakPolarHBondContact CA-O 3.41Å; N328-Q332 PolarHBondContact N-O 2.74Å; N328-Q332 PolarHBondContact OD1-N 3.38Å; N328-Q332 PolarHBondContact OD1-O 2.96Å; T330-Q332 PolarHBondContact OG1-OE1 3.46Å; Q332-D334 PolarHBondContact O-N 2.89Å; Q332-D334 VanDerWaalsContact O-N 3.12Å
333N85.4Confident92.9Very high23 Ų2337.5 Ų37.512%0.12321%0.207CC..THydrogen-bonded Turntrans-86.845.8-178.6-75.770.8000113.1R324 F326 H411 R457R324-N333 PolarHBondContact O-ND2 2.67Å; F326-N333 CarbonylContact O-C 3.56Å; F326-N333 VanDerWaalsContact O-CA 3.24Å; F326-N333 WeakPolarHBondContact O-CA 3.26Å; N333-H411 WeakPolarHBondContact CB-CE1 3.34Å; N333-H411 WeakPolarHBondContact CB-NE2 3.46Å; N333-H411 VanDerWaalsContact CG-CE1 3.43Å; N333-H411 PolarHBondContact ND2-CE1 2.98Å; N333-H411 PolarHBondContact ND2-ND1 2.62Å; N333-R457 PolarHBondContact O-NH1 3.3Å
334D87.9Confident92.9Very high90 Ų9039.5 Ų39.548%0.48122%0.217SC..THydrogen-bonded Turntrans-118.68.9177.168.4-2.9000112.8N328 Q332 R457N328-D334 VanDerWaalsContact CG-OD1 3.26Å; N328-D334 PolarHBondContact ND2-OD1 3.24Å; Q332-D334 PolarHBondContact O-N 2.89Å; Q332-D334 VanDerWaalsContact O-N 3.12Å; D334-R457 VanDerWaalsContact C-NH2 3.31Å; D334-R457 VanDerWaalsContact CA-NH1 3.33Å; D334-R457 PolarHBondContact O-NH2 3.1Å
335G93.5Very high93Very high7 Ų739.7 Ų39.77%0.07222%0.218CC..  trans-71-167.1178.900000114.6R457G335-R457 PolarHBondContact O-NH2 3.39Å
336T95.4Very high93Very high82 Ų8239.7 Ų39.750%0.50322%0.218SC..  trans-116.9179.2-179.967.10000111.4F326 R338 D339F326-T336 WeakPolarHBondContact CB-O 3.37Å; F326-T336 WeakPolarHBondContact CD1-O 3.39Å; F326-T336 VanDerWaalsContact CG-C 3.49Å; F326-T336 WeakPolarHBondContact CG-O 3.39Å; T336-R338 PolarHBondContact O-N 3.44Å; T336-R338 VanDerWaalsContact O-N 3.17Å; T336-R338 PolarHBondContact OG1-N 3.04Å; T336-D339 PolarHBondContact N-OD2 2.88Å; T336-D339 WeakPolarHBondContact O-CA 3.49Å; T336-D339 WeakPolarHBondContact O-CB 3.35Å; T336-D339 PolarHBondContact O-N 2.95Å; T336-D339 PolarHBondContact OG1-OD2 3.13Å
337L96.8Very high93.1Very high24 Ų2439.6 Ų39.613%0.12622%0.217CC..G310 helixtrans-55.7-32.9176.3-176.860.7000113.1L295 L311 F321 F326 D339 T340L295-L337 HydrophobicContact CD1-CB 4.41Å; L295-L337 HydrophobicContact CD1-CD2 4.5Å; L295-L337 HydrophobicContact CD1-CG 4.38Å; L295-L337 HydrophobicContact CD2-CB 4.48Å; L295-L337 HydrophobicContact CD2-CD2 3.99Å; L295-L337 HydrophobicContact CD2-CG 3.69Å; L311-L337 HydrophobicContact CD2-CD1 3.93Å; L311-L337 HydrophobicContact CD2-CG 4.38Å; F321-L337 HydrophobicContact CB-CD1 3.56Å; F321-L337 HydrophobicContact CD1-CD1 3.76Å; F321-L337 HydrophobicContact CD2-CD1 3.51Å; F321-L337 HydrophobicContact CD2-CD2 4.19Å; F321-L337 HydrophobicContact CE1-CD1 4.35Å; F321-L337 HydrophobicContact CE2-CD1 4.13Å; F321-L337 HydrophobicContact CG-CD1 3.29Å; F326-L337 HydrophobicContact CE1-CB 4.26Å; F326-L337 HydrophobicContact CE1-CD1 3.71Å; F326-L337 HydrophobicContact CE2-CB 4.46Å; F326-L337 HydrophobicContact CZ-CB 3.9Å; F326-L337 HydrophobicContact CZ-CD1 3.8Å; F326-L337 HydrophobicContact CZ-CG 4.48Å; L337-D339 PolarHBondContact O-N 3.09Å; L337-T340 WeakPolarHBondContact O-CB 3.17Å; L337-T340 PolarHBondContact O-N 3.33Å; L337-T340 VanDerWaalsContact O-N 3.16Å; L337-T340 PolarHBondContact O-OG1 3.26Å
338R96.4Very high93.3Very high87 Ų8739.4 Ų39.433%0.32822%0.216SC..G310 helixtrans-67-19.6175.8-169.1173.8172.8125.9-10.5113.1L295 E297 T336 T340L295-R338 HydrophobicContact CD1-CB 3.86Å; L295-R338 HydrophobicContact CD1-CG 4.49Å; L295-R338 HydrophobicContact CG-CB 4.32Å; L295-R338 PolarHBondContact O-NH1 2.83Å; E297-R338 VanDerWaalsContact O-CZ 3.24Å; E297-R338 PolarHBondContact O-NH1 3.41Å; E297-R338 PolarHBondContact O-NH2 3.15Å; T336-R338 PolarHBondContact O-N 3.44Å; T336-R338 VanDerWaalsContact O-N 3.17Å; T336-R338 PolarHBondContact OG1-N 3.04Å; R338-T340 VanDerWaalsContact C-N 3.35Å
339D95.9Very high93.8Very high46 Ų4639 Ų3925%0.24621%0.214CC..G310 helixtrans-95.214.4178.1-52.7-65.3000112.3I327 T336 L337 R341I327-D339 PolarHBondContact N-O 2.81Å; T336-D339 PolarHBondContact N-OD2 2.88Å; T336-D339 WeakPolarHBondContact O-CA 3.49Å; T336-D339 WeakPolarHBondContact O-CB 3.35Å; T336-D339 PolarHBondContact O-N 2.95Å; T336-D339 PolarHBondContact OG1-OD2 3.13Å; L337-D339 PolarHBondContact O-N 3.09Å; D339-R341 PolarHBondContact O-N 2.94Å
340T97.3Very high94.4Very high0 Ų033.1 Ų33.10%017%0.173CC..BIsolated β-bridgetrans-58.9127.7178.4-60.90000110.9D310 W325 F326 L337 R338 T342D310-T340 HydrophobicContact CB-CG2 4.08Å; D310-T340 WeakPolarHBondContact CB-O 3.31Å; W325-T340 HydrophobicContact CB-CG2 3.95Å; W325-T340 WeakPolarHBondContact O-CA 3.47Å; F326-T340 WeakPolarHBondContact CD1-OG1 3.45Å; F326-T340 VanDerWaalsContact CE1-OG1 3.26Å; F326-T340 WeakPolarHBondContact CE1-OG1 3.41Å; L337-T340 WeakPolarHBondContact O-CB 3.17Å; L337-T340 PolarHBondContact O-N 3.33Å; L337-T340 VanDerWaalsContact O-N 3.16Å; L337-T340 PolarHBondContact O-OG1 3.26Å; R338-T340 VanDerWaalsContact C-N 3.35Å; T340-T342 VanDerWaalsContact CG2-OG1 3.23Å; T340-T342 WeakPolarHBondContact CG2-OG1 3.33Å
341R97.3Very high95.1Very high49 Ų4928.8 Ų28.819%0.18515%0.146CC..  trans-137.444.7-180-67.9-64.8-178.1-86.6-5.3111.1W325 I327 D339 S343 Q344W325-R341 PolarHBondContact O-N 3.21Å; I327-R341 HydrophobicContact CB-CB 3.99Å; I327-R341 HydrophobicContact CB-CG 4.07Å; I327-R341 HydrophobicContact CD1-CB 3.87Å; I327-R341 HydrophobicContact CG1-CB 4.14Å; D339-R341 PolarHBondContact O-N 2.94Å; R341-S343 PolarHBondContact O-N 2.89Å; R341-Q344 HydrophobicContact CB-CB 4.25Å; R341-Q344 HydrophobicContact CB-CG 4.3Å; R341-Q344 WeakPolarHBondContact O-CA 3.45Å; R341-Q344 WeakPolarHBondContact O-CB 3.33Å; R341-Q344 PolarHBondContact O-N 2.88Å
342T98.3Very high95.9Very high0 Ų028.2 Ų28.20%014%0.14CC..G310 helixtrans-53.5-39.3-176.2-41.60000112.7F277 D310 A313 W325 T340 Q344 I345F277-T342 HydrophobicContact CB-CG2 4.3Å; D310-T342 PolarHBondContact O-OG1 3.3Å; D310-T342 PolarHBondContact OD1-N 2.86Å; A313-T342 HydrophobicContact CB-CG2 4.06Å; W325-T342 HydrophobicContact CD2-CG2 3.87Å; W325-T342 HydrophobicContact CE3-CG2 4.06Å; W325-T342 HydrophobicContact CG-CG2 4.19Å; W325-T342 HydrophobicContact CZ3-CG2 4.46Å; T340-T342 VanDerWaalsContact CG2-OG1 3.23Å; T340-T342 WeakPolarHBondContact CG2-OG1 3.33Å; T342-Q344 PolarHBondContact O-N 3.18Å; T342-Q344 VanDerWaalsContact O-N 3.13Å; T342-I345 PolarHBondContact O-N 3.17Å
343S97.4Very high96.6Very high2 Ų223 Ų231%0.01412%0.116CC..G310 helixtrans-66.8-9.5176.967.20000114R276 F277 Q306 D310 R341R276-S343 WeakPolarHBondContact CD-O 3.32Å; R276-S343 VanDerWaalsContact CZ-O 3.22Å; R276-S343 PolarHBondContact NE-O 3.1Å; R276-S343 PolarHBondContact NH1-O 3.36Å; F277-S343 WeakPolarHBondContact O-CA 3.23Å; Q306-S343 PolarHBondContact NE2-OG 3.23Å; D310-S343 WeakPolarHBondContact OD1-CB 3.39Å; D310-S343 PolarHBondContact OD1-N 3.18Å; D310-S343 PolarHBondContact OD1-OG 3.36Å; R341-S343 PolarHBondContact O-N 2.89Å
344Q97.4Very high97.2Very high43 Ų4322 Ų2220%0.20111%0.11CC..G310 helixtrans-102.912.4178.2-56.2-57.3-4200113R341 T342 L405 L406R341-Q344 HydrophobicContact CB-CB 4.25Å; R341-Q344 HydrophobicContact CB-CG 4.3Å; R341-Q344 WeakPolarHBondContact O-CA 3.45Å; R341-Q344 WeakPolarHBondContact O-CB 3.33Å; R341-Q344 PolarHBondContact O-N 2.88Å; T342-Q344 PolarHBondContact O-N 3.18Å; T342-Q344 VanDerWaalsContact O-N 3.13Å; Q344-L405 VanDerWaalsContact O-CB 3.32Å; Q344-L405 WeakPolarHBondContact O-CB 3.45Å; Q344-L405 WeakPolarHBondContact O-CG 3.13Å; Q344-L405 PolarHBondContact O-N 3.27Å; Q344-L406 HydrophobicContact CB-CD1 4.12Å; Q344-L406 HydrophobicContact CB-CD2 4.39Å; Q344-L406 HydrophobicContact CB-CG 3.9Å; Q344-L406 HydrophobicContact CG-CD1 4.17Å; Q344-L406 HydrophobicContact CG-CD2 4.04Å; Q344-L406 HydrophobicContact CG-CG 4.05Å
345I98.4Very high97.8Very high4 Ų417.7 Ų17.72%0.0219%0.088CC..EExtended strand (participates in β ladder)trans-120.6135-178-64.6166.9000109R276 R324 W325 I327 T342 P347 D402 Y403R276-I345 VanDerWaalsContact CB-O 3.3Å; R276-I345 WeakPolarHBondContact CB-O 3.48Å; R324-I345 WeakPolarHBondContact O-CD1 3.5Å; W325-I345 HydrophobicContact CE3-CB 4.49Å; W325-I345 HydrophobicContact CE3-CD1 3.7Å; W325-I345 HydrophobicContact CE3-CG2 4.39Å; W325-I345 HydrophobicContact CZ3-CB 4.43Å; W325-I345 HydrophobicContact CZ3-CD1 4.38Å; W325-I345 HydrophobicContact CZ3-CG2 3.99Å; I327-I345 HydrophobicContact CD1-CD1 3.74Å; I327-I345 HydrophobicContact CD1-CG1 3.68Å; I327-I345 HydrophobicContact CG1-CD1 4.21Å; T342-I345 PolarHBondContact O-N 3.17Å; I345-P347 VanDerWaalsContact O-CD 3.23Å; I345-P347 WeakPolarHBondContact O-CD 3.37Å; I345-D402 HydrophobicContact CG2-CB 3.64Å; I345-Y403 WeakPolarHBondContact CA-O 3.15Å
346L98.7Very high98Very high0 Ų018.4 Ų18.40%09%0.088CC..EExtended strand (participates in β ladder)trans-90.2104.3165.8-57-176.3000108.7I263 V265 L274 R276 L391 L392 D402 Y403 L405I263-L346 HydrophobicContact CG2-CD2 3.61Å; V265-L346 HydrophobicContact CG2-CD1 4.08Å; L274-L346 HydrophobicContact CB-CD1 4.2Å; L274-L346 HydrophobicContact CB-CD2 4.48Å; L274-L346 HydrophobicContact CD1-CD1 3.97Å; R276-L346 HydrophobicContact CB-CD2 4.2Å; L346-L391 HydrophobicContact CD1-CD1 4.28Å; L346-L392 HydrophobicContact CB-CD2 4.23Å; L346-D402 WeakPolarHBondContact O-CA 3.39Å; L346-Y403 HydrophobicContact CD1-CD1 4.13Å; L346-Y403 PolarHBondContact N-O 3.07Å; L346-Y403 PolarHBondContact O-N 2.91Å; L346-L405 HydrophobicContact CD1-CD2 4.06Å; L346-L405 HydrophobicContact CD2-CD1 4.05Å; L346-L405 HydrophobicContact CD2-CD2 4.15Å; L346-L405 HydrophobicContact CD2-CG 4.37Å; L346-L405 HydrophobicContact CG-CD1 4.43Å; L346-L405 HydrophobicContact CG-CD2 3.9Å; L346-L405 HydrophobicContact CG-CG 4.21Å
347P98.7Very high98.2Very high0 Ų014.7 Ų14.70%07%0.065CC..  trans-79.2134.7-172.9-14.533.1000111.2N275 F277 W325 I345 D349 L350 N351 D402N275-P347 WeakPolarHBondContact O-CD 3.41Å; F277-P347 HydrophobicContact CD2-CG 3.75Å; F277-P347 HydrophobicContact CE2-CB 4.2Å; F277-P347 HydrophobicContact CE2-CG 3.89Å; W325-P347 HydrophobicContact CH2-CB 4.26Å; W325-P347 HydrophobicContact CH2-CG 4.34Å; W325-P347 HydrophobicContact CZ3-CG 4.39Å; I345-P347 VanDerWaalsContact O-CD 3.23Å; I345-P347 WeakPolarHBondContact O-CD 3.37Å; P347-D349 WeakPolarHBondContact CB-OD1 3.4Å; P347-L350 HydrophobicContact CB-CB 4.12Å; P347-L350 HydrophobicContact CG-CB 4.38Å; P347-N351 PolarHBondContact O-N 2.71Å; P347-N351 PolarHBondContact O-ND2 3.27Å; P347-D402 VanDerWaalsContact CA-OD1 3.31Å; P347-D402 WeakPolarHBondContact CA-OD1 3.33Å
348V98.8Very high98.3Very high0 Ų013.7 Ų13.70%06%0.06CC..Hα-helixtrans-60.3-46.7177.8171.90000111.8N351 A352 L392 W400 F401 D402 S417 P421V348-N351 PolarHBondContact O-N 3.34Å; V348-A352 VanDerWaalsContact O-CB 3.28Å; V348-A352 WeakPolarHBondContact O-CB 3.35Å; V348-A352 PolarHBondContact O-N 2.59Å; V348-L392 HydrophobicContact CG2-CB 4.26Å; V348-L392 HydrophobicContact CG2-CD1 4.17Å; V348-W400 HydrophobicContact CB-CB 4.46Å; V348-W400 HydrophobicContact CG1-CB 3.61Å; V348-W400 HydrophobicContact CG1-CG 4.44Å; V348-W400 HydrophobicContact CG2-CB 3.91Å; V348-F401 WeakPolarHBondContact CG2-O 3.49Å; V348-D402 WeakPolarHBondContact CG2-OD1 3.49Å; V348-D402 PolarHBondContact N-OD1 3.44Å; V348-S417 VanDerWaalsContact CG1-O 3.27Å; V348-S417 WeakPolarHBondContact CG1-O 3.29Å; V348-P421 HydrophobicContact CG1-CG 3.56Å
349D98.8Very high98.4Very high20 Ų2013.3 Ų13.311%0.1076%0.061CC..Hα-helixtrans-63.2-46.8-17949.3-4.7000113.3R324 P347 N351 A352 L353 A420R324-D349 IonicContact CZ-OD1 3.53Å; R324-D349 IonicContact CZ-OD2 3.22Å; R324-D349 IonicContact NH1-OD1 3.24Å; R324-D349 IonicContact NH1-OD2 3.46Å; R324-D349 PolarHBondContact NH1-OD2 3.08Å; R324-D349 IonicContact NH2-OD1 3.61Å; R324-D349 PolarHBondContact NH2-OD1 2.95Å; R324-D349 IonicContact NH2-OD2 3.53Å; R324-D349 PolarHBondContact NH2-OD2 3.33Å; P347-D349 WeakPolarHBondContact CB-OD1 3.4Å; D349-N351 VanDerWaalsContact C-N 3.3Å; D349-N351 PolarHBondContact O-N 3.34Å; D349-A352 PolarHBondContact O-N 2.81Å; D349-L353 VanDerWaalsContact O-CB 3.3Å; D349-L353 WeakPolarHBondContact O-CB 3.42Å; D349-L353 PolarHBondContact O-N 2.77Å; D349-A420 HydrophobicContact CB-CB 3.95Å
350L98.9Very high98.5Very high2 Ų211.6 Ų11.61%0.015%0.052CC..Hα-helixtrans-58-45.2176.7176.957.9000111.4P224 W257 N275 F277 P347 L353 L354P224-L350 HydrophobicContact CG-CD1 4.35Å; W257-L350 HydrophobicContact CE3-CD1 3.91Å; W257-L350 HydrophobicContact CE3-CD2 4.41Å; W257-L350 HydrophobicContact CH2-CD1 4.16Å; W257-L350 HydrophobicContact CZ3-CD1 3.65Å; W257-L350 HydrophobicContact CZ3-CD2 4.01Å; W257-L350 HydrophobicContact CZ3-CG 4.48Å; N275-L350 HydrophobicContact CB-CD2 3.88Å; N275-L350 HydrophobicContact CB-CG 4.22Å; F277-L350 HydrophobicContact CD1-CD2 4.09Å; F277-L350 HydrophobicContact CD2-CD2 4.28Å; F277-L350 HydrophobicContact CE1-CD1 3.89Å; F277-L350 HydrophobicContact CE1-CD2 3.93Å; F277-L350 HydrophobicContact CE1-CG 4.33Å; F277-L350 HydrophobicContact CE2-CB 3.93Å; F277-L350 HydrophobicContact CE2-CD2 4.1Å; F277-L350 HydrophobicContact CE2-CG 4.48Å; F277-L350 HydrophobicContact CG-CD2 4.28Å; F277-L350 HydrophobicContact CZ-CB 3.78Å; F277-L350 HydrophobicContact CZ-CD1 3.91Å; F277-L350 HydrophobicContact CZ-CD2 3.93Å; F277-L350 HydrophobicContact CZ-CG 4.07Å; P347-L350 HydrophobicContact CB-CB 4.12Å; P347-L350 HydrophobicContact CG-CB 4.38Å; L350-L353 PolarHBondContact O-N 2.7Å; L350-L354 HydrophobicContact CD1-CD1 4.05Å; L350-L354 HydrophobicContact CD1-CG 4.24Å; L350-L354 HydrophobicContact CG-CD1 4.17Å; L350-L354 WeakPolarHBondContact O-CG 3.11Å; L350-L354 PolarHBondContact O-N 2.96Å
351N98.9Very high98.6Very high0 Ų011.6 Ų11.60%05%0.052CC..Hα-helixtrans-74.8-33-178-72-75.8000112.3L274 N275 P347 V348 D349 C355 R384 M388 L392L274-N351 WeakPolarHBondContact CB-OD1 3.46Å; L274-N351 HydrophobicContact CD2-CB 4.17Å; L274-N351 WeakPolarHBondContact CD2-OD1 3.45Å; N275-N351 PolarHBondContact N-OD1 2.85Å; N275-N351 PolarHBondContact O-ND2 2.81Å; P347-N351 PolarHBondContact O-N 2.71Å; P347-N351 PolarHBondContact O-ND2 3.27Å; V348-N351 PolarHBondContact O-N 3.34Å; D349-N351 VanDerWaalsContact C-N 3.3Å; D349-N351 PolarHBondContact O-N 3.34Å; N351-C355 WeakPolarHBondContact O-CB 3.48Å; N351-C355 PolarHBondContact O-N 3.48Å; N351-R384 WeakPolarHBondContact O-CD 3.4Å; N351-R384 PolarHBondContact OD1-NH1 2.87Å; N351-M388 VanDerWaalsContact C-SD 3.58Å; N351-M388 HydrophobicContact CB-CE 4.28Å; N351-M388 HydrophobicContact CB-CG 3.99Å; N351-M388 HydrophobicContact CB-SD 3.93Å; N351-L392 HydrophobicContact CB-CD1 4.39Å
352A98.9Very high98.7Very high0 Ų09.4 Ų9.40%04%0.044CC..Hα-helixtrans-61.9-45169.800000111.4V348 D349 C355 R356 M388 A420 P421 A424V348-A352 VanDerWaalsContact O-CB 3.28Å; V348-A352 WeakPolarHBondContact O-CB 3.35Å; V348-A352 PolarHBondContact O-N 2.59Å; D349-A352 PolarHBondContact O-N 2.81Å; A352-C355 WeakPolarHBondContact O-CB 3.32Å; A352-C355 PolarHBondContact O-N 3.33Å; A352-R356 PolarHBondContact O-N 3.42Å; A352-M388 HydrophobicContact CB-CE 3.94Å; A352-A420 HydrophobicContact CB-CB 4.06Å; A352-P421 HydrophobicContact CB-CB 4.49Å; A352-P421 HydrophobicContact CB-CG 4.09Å; A352-A424 HydrophobicContact CB-CB 3.87Å; A352-A424 VanDerWaalsContact O-CB 3.32Å; A352-A424 WeakPolarHBondContact O-CB 3.42Å
353L98.9Very high98.7Very high5 Ų511.9 Ų11.93%0.0266%0.061CC..Hα-helixtrans-65.1-44.3178.8-177.756.9000111.9P223 P224 F225 L228 D349 L350 C355 R356 N357 W423P223-L353 HydrophobicContact CB-CD2 3.8Å; P224-L353 HydrophobicContact CG-CD2 4.04Å; P224-L353 HydrophobicContact CG-CG 4.26Å; F225-L353 HydrophobicContact CD1-CD1 4.38Å; F225-L353 HydrophobicContact CD2-CD1 4.38Å; F225-L353 HydrophobicContact CD2-CD2 3.63Å; F225-L353 HydrophobicContact CE1-CD1 4.28Å; F225-L353 HydrophobicContact CE2-CD1 4.26Å; F225-L353 HydrophobicContact CE2-CD2 3.47Å; F225-L353 VanDerWaalsContact CE2-CD2 3.47Å; F225-L353 HydrophobicContact CG-CD1 4.43Å; F225-L353 HydrophobicContact CG-CD2 4.4Å; F225-L353 HydrophobicContact CZ-CD1 4.21Å; F225-L353 HydrophobicContact CZ-CD2 4.14Å; L228-L353 HydrophobicContact CD1-CD1 3.72Å; L228-L353 HydrophobicContact CD2-CD1 4.35Å; D349-L353 VanDerWaalsContact O-CB 3.3Å; D349-L353 WeakPolarHBondContact O-CB 3.42Å; D349-L353 PolarHBondContact O-N 2.77Å; L350-L353 PolarHBondContact O-N 2.7Å; L353-C355 VanDerWaalsContact C-N 3.31Å; L353-C355 PolarHBondContact O-N 3.28Å; L353-R356 CarbonylContact O-C 3.23Å; L353-R356 WeakPolarHBondContact O-CB 3.39Å; L353-R356 PolarHBondContact O-N 2.85Å; L353-R356 VanDerWaalsContact O-N 3.14Å; L353-N357 PolarHBondContact O-N 3.03Å; L353-N357 PolarHBondContact O-OD1 3.43Å; L353-W423 HydrophobicContact CD1-CH2 3.89Å; L353-W423 HydrophobicContact CD1-CZ3 3.99Å
354L98.9Very high98.8Very high0 Ų012 Ų120%06%0.061CC..Hα-helixtrans-65-34.7175.2-72.1172.1000112.5P224 Y254 W257 N275 L350 R356 N357 E358P224-L354 HydrophobicContact CG-CD2 3.88Å; P224-L354 HydrophobicContact CG-CG 4.41Å; Y254-L354 HydrophobicContact CD2-CD2 4.48Å; W257-L354 HydrophobicContact CB-CD1 4.44Å; W257-L354 HydrophobicContact CB-CD2 3.99Å; W257-L354 HydrophobicContact CG-CD2 4.03Å; N275-L354 HydrophobicContact CB-CD1 3.51Å; N275-L354 WeakPolarHBondContact OD1-CD1 3.47Å; L350-L354 HydrophobicContact CD1-CD1 4.05Å; L350-L354 HydrophobicContact CD1-CG 4.24Å; L350-L354 HydrophobicContact CG-CD1 4.17Å; L350-L354 WeakPolarHBondContact O-CG 3.11Å; L350-L354 PolarHBondContact O-N 2.96Å; L354-R356 VanDerWaalsContact C-N 3.34Å; L354-N357 PolarHBondContact O-N 3.47Å; L354-E358 VanDerWaalsContact O-CG 3.28Å; L354-E358 WeakPolarHBondContact O-CG 3.44Å; L354-E358 PolarHBondContact O-N 3.32Å
355C98.9Very high98.8Very high0 Ų010.4 Ų10.40%05%0.054CC..Hα-helixtrans-62.8-42.4171.7168.90000111.3N351 A352 L353 E358 K359 R384 M388 C426N351-C355 WeakPolarHBondContact O-CB 3.48Å; N351-C355 PolarHBondContact O-N 3.48Å; A352-C355 WeakPolarHBondContact O-CB 3.32Å; A352-C355 PolarHBondContact O-N 3.33Å; L353-C355 VanDerWaalsContact C-N 3.31Å; L353-C355 PolarHBondContact O-N 3.28Å; C355-E358 PolarHBondContact O-N 2.79Å; C355-K359 WeakPolarHBondContact O-CG 3.35Å; C355-K359 PolarHBondContact O-N 3.2Å; C355-K359 VanDerWaalsContact O-N 3.11Å; C355-R384 HydrophobicContact CB-CG 4.26Å; C355-R384 VanDerWaalsContact N-CD 3.35Å; C355-M388 HydrophobicContact CB-SD 4.4Å; C355-C426 VanDerWaalsContact C-SG 3.54Å; C355-C426 HydrophobicContact CB-CB 3.73Å; C355-C426 WeakPolarHBondContact CB-SG 3.4Å; C355-C426 WeakPolarHBondContact SG-CB 3.24Å; C355-C426 CovalentContact SG-SG 2.03Å; C355-C426 PolarHBondContact SG-SG 2.81Å
356R98.8Very high98.8Very high23 Ų2316 Ų169%0.0878%0.075CC..Hα-helixtrans-63-42.1173.4-175.5166.8175.5177.7-1.1111.2L228 E231 A352 L353 L354 E358 K359 L360 A424L228-R356 HydrophobicContact CD1-CG 4.49Å; L228-R356 VanDerWaalsContact CD2-CZ 3.49Å; E231-R356 IonicContact OE2-NH2 2.72Å; E231-R356 PolarHBondContact OE2-NH2 3.28Å; E231-R356 VanDerWaalsContact OE2-NH2 3.1Å; A352-R356 PolarHBondContact O-N 3.42Å; L353-R356 CarbonylContact O-C 3.23Å; L353-R356 WeakPolarHBondContact O-CB 3.39Å; L353-R356 PolarHBondContact O-N 2.85Å; L353-R356 VanDerWaalsContact O-N 3.14Å; L354-R356 VanDerWaalsContact C-N 3.34Å; R356-E358 PolarHBondContact O-N 3.09Å; R356-K359 WeakPolarHBondContact O-CB 3.34Å; R356-K359 PolarHBondContact O-N 3.04Å; R356-L360 HydrophobicContact CG-CD1 4.35Å; R356-L360 HydrophobicContact CG-CG 4.5Å; R356-L360 WeakPolarHBondContact O-CG 3.24Å; R356-L360 PolarHBondContact O-N 3.31Å; R356-A424 HydrophobicContact CB-CB 4.16Å
357N98.9Very high98.8Very high4 Ų419.7 Ų19.72%0.0219%0.094CC..Hα-helixtrans-61-44.1176.5-70.6-4000112P224 P227 L228 L353 L354 K359 L360 L361P224-N357 PolarHBondContact O-ND2 3.04Å; P227-N357 HydrophobicContact CG-CB 4.23Å; L228-N357 WeakPolarHBondContact CD1-OD1 3.35Å; L353-N357 PolarHBondContact O-N 3.03Å; L353-N357 PolarHBondContact O-OD1 3.43Å; L354-N357 PolarHBondContact O-N 3.47Å; N357-K359 VanDerWaalsContact C-N 3.32Å; N357-K359 PolarHBondContact O-N 3.06Å; N357-L360 PolarHBondContact O-N 2.79Å; N357-L360 VanDerWaalsContact O-N 3.16Å; N357-L361 VanDerWaalsContact O-CG 3.31Å; N357-L361 WeakPolarHBondContact O-CG 3.48Å; N357-L361 PolarHBondContact O-N 3.03Å
358E98.9Very high98.8Very high3 Ų321.7 Ų21.71%0.01411%0.105CC..Hα-helixtrans-59.6-42.3175.6-70.9158.1171.200111.3Y254 L354 C355 R356 L360 L361 A362 Y377 A380 A381 R384Y254-E358 HydrophobicContact CD2-CG 4.5Å; Y254-E358 HydrophobicContact CE2-CG 3.53Å; Y254-E358 PolarHBondContact OH-OE1 2.9Å; L354-E358 VanDerWaalsContact O-CG 3.28Å; L354-E358 WeakPolarHBondContact O-CG 3.44Å; L354-E358 PolarHBondContact O-N 3.32Å; C355-E358 PolarHBondContact O-N 2.79Å; R356-E358 PolarHBondContact O-N 3.09Å; E358-L360 PolarHBondContact O-N 3.08Å; E358-L361 PolarHBondContact O-N 3.21Å; E358-A362 WeakPolarHBondContact O-CB 3.27Å; E358-A362 PolarHBondContact O-N 2.83Å; E358-Y377 WeakPolarHBondContact O-CB 3.16Å; E358-A380 HydrophobicContact CB-CB 4.5Å; E358-A380 HydrophobicContact CG-CB 4.03Å; E358-A381 HydrophobicContact CB-CB 3.84Å; E358-A381 VanDerWaalsContact OE2-CA 3.23Å; E358-A381 WeakPolarHBondContact OE2-CA 3.47Å; E358-A381 PolarHBondContact OE2-N 2.75Å; E358-R384 IonicContact OE1-CZ 3.24Å; E358-R384 VanDerWaalsContact OE1-CZ 3.23Å; E358-R384 IonicContact OE1-NE 2.74Å; E358-R384 PolarHBondContact OE1-NE 2.61Å; E358-R384 IonicContact OE1-NH2 3.45Å; E358-R384 PolarHBondContact OE1-NH2 3.12Å; E358-R384 WeakPolarHBondContact OE2-CB 3.41Å; E358-R384 WeakPolarHBondContact OE2-CD 3.31Å; E358-R384 IonicContact OE2-NE 2.79Å; E358-R384 PolarHBondContact OE2-NE 3.21Å; E358-R384 VanDerWaalsContact OE2-NE 3.07Å
359K98.9Very high98.7Very high78 Ų7824.4 Ų24.434%0.33913%0.133SC..Hα-helixtrans-63.4-39.8174.3-69.6179177.1-167.90112.7C355 R356 N357 A362 S363 A381 Q425C355-K359 WeakPolarHBondContact O-CG 3.35Å; C355-K359 PolarHBondContact O-N 3.2Å; C355-K359 VanDerWaalsContact O-N 3.11Å; R356-K359 WeakPolarHBondContact O-CB 3.34Å; R356-K359 PolarHBondContact O-N 3.04Å; N357-K359 VanDerWaalsContact C-N 3.32Å; N357-K359 PolarHBondContact O-N 3.06Å; K359-A362 PolarHBondContact O-N 2.77Å; K359-S363 WeakPolarHBondContact O-CB 3.02Å; K359-S363 PolarHBondContact O-N 3.22Å; K359-A381 HydrophobicContact CG-CB 3.96Å; K359-Q425 PolarHBondContact NZ-O 3.37Å
360L98.8Very high98.7Very high11 Ų1126.3 Ų26.36%0.05814%0.143CC..Hα-helixtrans-67.4-45.9177.4-69.3177.6000112P227 L228 E231 R356 N357 E358 A362 S363 F364P227-L360 HydrophobicContact CB-CB 4.43Å; P227-L360 HydrophobicContact CB-CD1 4.05Å; L228-L360 HydrophobicContact CB-CD1 4.46Å; L228-L360 HydrophobicContact CD1-CD1 3.86Å; L228-L360 HydrophobicContact CG-CD1 3.83Å; E231-L360 HydrophobicContact CB-CD1 4.35Å; E231-L360 HydrophobicContact CB-CD2 4.17Å; E231-L360 HydrophobicContact CG-CD2 4.04Å; E231-L360 WeakPolarHBondContact OE1-CD2 3.38Å; R356-L360 HydrophobicContact CG-CD1 4.35Å; R356-L360 HydrophobicContact CG-CG 4.5Å; R356-L360 WeakPolarHBondContact O-CG 3.24Å; R356-L360 PolarHBondContact O-N 3.31Å; N357-L360 PolarHBondContact O-N 2.79Å; N357-L360 VanDerWaalsContact O-N 3.16Å; E358-L360 PolarHBondContact O-N 3.08Å; L360-A362 VanDerWaalsContact C-N 3.28Å; L360-A362 PolarHBondContact O-N 3.36Å; L360-S363 WeakPolarHBondContact O-CB 3.12Å; L360-S363 PolarHBondContact O-N 2.92Å; L360-S363 VanDerWaalsContact O-N 3.09Å; L360-F364 HydrophobicContact CB-CE2 4.13Å; L360-F364 HydrophobicContact CB-CZ 4.23Å; L360-F364 WeakPolarHBondContact O-CB 3.49Å; L360-F364 WeakPolarHBondContact O-CD2 3.16Å; L360-F364 WeakPolarHBondContact O-CG 3.42Å; L360-F364 PolarHBondContact O-N 3.2Å
361L98.9Very high98.6Very high0 Ų031.2 Ų31.20%017%0.169CC..Hα-helixtrans-58.6-42.4175.7-68.3173.4000111L247 L250 E251 Y254 N357 E358 F364 H365 Y377L247-L361 HydrophobicContact CD1-CD2 3.64Å; L250-L361 HydrophobicContact CB-CD2 3.91Å; E251-L361 HydrophobicContact CG-CD2 4.13Å; Y254-L361 HydrophobicContact CD1-CD1 4.22Å; Y254-L361 HydrophobicContact CD2-CD1 4.25Å; Y254-L361 HydrophobicContact CG-CD1 3.85Å; N357-L361 VanDerWaalsContact O-CG 3.31Å; N357-L361 WeakPolarHBondContact O-CG 3.48Å; N357-L361 PolarHBondContact O-N 3.03Å; E358-L361 PolarHBondContact O-N 3.21Å; L361-F364 PolarHBondContact O-N 2.98Å; L361-H365 WeakPolarHBondContact O-CB 3.45Å; L361-H365 PolarHBondContact O-CD2 3.16Å; L361-H365 VanDerWaalsContact O-CD2 3.22Å; L361-H365 PolarHBondContact O-N 2.83Å; L361-Y377 HydrophobicContact CB-CD1 3.91Å; L361-Y377 HydrophobicContact CB-CD2 3.88Å; L361-Y377 HydrophobicContact CB-CE1 4.18Å; L361-Y377 HydrophobicContact CB-CE2 4.16Å; L361-Y377 HydrophobicContact CB-CG 3.77Å; L361-Y377 HydrophobicContact CD1-CD1 3.84Å; L361-Y377 HydrophobicContact CD1-CE1 3.51Å; L361-Y377 HydrophobicContact CG-CE1 4.47Å
362A98.9Very high98.6Very high3 Ų339 Ų393%0.02521%0.205CC..Hα-helixtrans-59.5-46.8173.200000112.6E358 K359 L360 H365 R366 A374 E378E358-A362 WeakPolarHBondContact O-CB 3.27Å; E358-A362 PolarHBondContact O-N 2.83Å; K359-A362 PolarHBondContact O-N 2.77Å; L360-A362 VanDerWaalsContact C-N 3.28Å; L360-A362 PolarHBondContact O-N 3.36Å; A362-H365 PolarHBondContact O-N 3.35Å; A362-R366 WeakPolarHBondContact O-CB 3.35Å; A362-R366 PolarHBondContact O-N 3.25Å; A362-A374 WeakPolarHBondContact O-CB 3.41Å; A362-E378 HydrophobicContact CB-CG 3.74Å
363S98.8Very high98.6Very high52 Ų5240.5 Ų40.536%0.36422%0.216SC..Hα-helixtrans-61.5-46.8178.4-174.60000112K359 L360 H365 R366 L367K359-S363 WeakPolarHBondContact O-CB 3.02Å; K359-S363 PolarHBondContact O-N 3.22Å; L360-S363 WeakPolarHBondContact O-CB 3.12Å; L360-S363 PolarHBondContact O-N 2.92Å; L360-S363 VanDerWaalsContact O-N 3.09Å; S363-H365 PolarHBondContact O-N 3.27Å; S363-R366 WeakPolarHBondContact O-CB 3.43Å; S363-R366 PolarHBondContact O-N 2.67Å; S363-L367 WeakPolarHBondContact O-CB 3.49Å; S363-L367 WeakPolarHBondContact O-CG 3.5Å; S363-L367 PolarHBondContact O-N 3.01Å
364F98.8Very high98.6Very high4 Ų440.2 Ų40.22%0.01822%0.215CC..Hα-helixtrans-62.2-44.2178.9-62.6-22000112A230 E231 L243 L247 L250 L360 L361 R366 L367 L368A230-F364 HydrophobicContact CB-CE2 4.43Å; A230-F364 HydrophobicContact CB-CZ 4.49Å; E231-F364 HydrophobicContact CB-CE1 4.4Å; E231-F364 HydrophobicContact CB-CZ 3.98Å; L243-F364 HydrophobicContact CD1-CB 4.22Å; L243-F364 HydrophobicContact CD1-CD1 3.79Å; L243-F364 HydrophobicContact CD1-CD2 3.86Å; L243-F364 HydrophobicContact CD1-CE1 4.01Å; L243-F364 HydrophobicContact CD1-CE2 4.07Å; L243-F364 HydrophobicContact CD1-CG 3.7Å; L243-F364 HydrophobicContact CD1-CZ 4.14Å; L243-F364 HydrophobicContact CD2-CB 4.2Å; L243-F364 HydrophobicContact CD2-CD1 3.83Å; L243-F364 HydrophobicContact CD2-CE1 4.48Å; L243-F364 HydrophobicContact CD2-CG 4.16Å; L243-F364 HydrophobicContact CG-CB 4.39Å; L243-F364 HydrophobicContact CG-CD1 4.37Å; L243-F364 HydrophobicContact CG-CG 4.33Å; L247-F364 HydrophobicContact CD1-CB 3.91Å; L247-F364 HydrophobicContact CD1-CD2 4.14Å; L247-F364 HydrophobicContact CD2-CB 4.13Å; L250-F364 HydrophobicContact CD1-CD2 4.08Å; L250-F364 HydrophobicContact CD1-CE2 3.87Å; L360-F364 HydrophobicContact CB-CE2 4.13Å; L360-F364 HydrophobicContact CB-CZ 4.23Å; L360-F364 WeakPolarHBondContact O-CB 3.49Å; L360-F364 WeakPolarHBondContact O-CD2 3.16Å; L360-F364 WeakPolarHBondContact O-CG 3.42Å; L360-F364 PolarHBondContact O-N 3.2Å; L361-F364 PolarHBondContact O-N 2.98Å; F364-R366 VanDerWaalsContact C-N 3.34Å; F364-R366 PolarHBondContact O-N 3Å; F364-L367 HydrophobicContact CD1-CD1 4.42Å; F364-L367 PolarHBondContact O-N 3.48Å; F364-L368 WeakPolarHBondContact O-CG 3.48Å; F364-L368 PolarHBondContact O-N 3.2Å
365H98.8Very high98.6Very high10 Ų1041.9 Ų41.95%0.04623%0.228CC..Hα-helixtrans-60.3-43.6174.1-86.7-63.6000111.9E251 L361 A362 S363 L368 G369 N370 S373 A374 Y377E251-H365 IonicContact OE1-CD2 2.83Å; E251-H365 IonicContact OE1-CE1 3.74Å; E251-H365 IonicContact OE1-NE2 3.16Å; E251-H365 PolarHBondContact OE1-NE2 3.48Å; E251-H365 IonicContact OE2-CE1 3.49Å; E251-H365 IonicContact OE2-NE2 2.83Å; L361-H365 WeakPolarHBondContact O-CB 3.45Å; L361-H365 PolarHBondContact O-CD2 3.16Å; L361-H365 VanDerWaalsContact O-CD2 3.22Å; L361-H365 PolarHBondContact O-N 2.83Å; A362-H365 PolarHBondContact O-N 3.35Å; S363-H365 PolarHBondContact O-N 3.27Å; H365-L368 CarbonylContact O-C 3.58Å; H365-L368 PolarHBondContact O-N 2.86Å; H365-G369 PolarHBondContact O-N 3.18Å; H365-G369 VanDerWaalsContact O-N 3.12Å; H365-N370 HydrophobicContact CB-CB 4.28Å; H365-N370 PolarHBondContact ND1-ND2 2.91Å; H365-N370 PolarHBondContact O-N 3.33Å; H365-S373 VanDerWaalsContact CG-CB 3.46Å; H365-S373 WeakPolarHBondContact ND1-CB 3.33Å; H365-A374 HydrophobicContact CB-CB 4.03Å; H365-Y377 AromaticContact CD2-CD2 3.75Å; H365-Y377 AromaticContact CD2-CE2 3.64Å; H365-Y377 AromaticContact NE2-CE2 3.63Å
366R98.4Very high98.6Very high120 Ų12046 Ų4645%0.45325%0.25SC..Hα-helixtrans-62.5-45176.4-178.6170.3-69.7131.13112.4A362 S363 F364 L368 G369 A374 E378A362-R366 WeakPolarHBondContact O-CB 3.35Å; A362-R366 PolarHBondContact O-N 3.25Å; S363-R366 WeakPolarHBondContact O-CB 3.43Å; S363-R366 PolarHBondContact O-N 2.67Å; F364-R366 VanDerWaalsContact C-N 3.34Å; F364-R366 PolarHBondContact O-N 3Å; R366-L368 PolarHBondContact O-N 3.34Å; R366-G369 PolarHBondContact O-N 2.91Å; R366-A374 HydrophobicContact CB-CB 4.17Å; R366-E378 IonicContact CZ-OE1 3.42Å; R366-E378 IonicContact NH1-OE1 3.86Å; R366-E378 PolarHBondContact NH1-OE1 2.98Å; R366-E378 IonicContact NH2-OE1 2.63Å; R366-E378 PolarHBondContact NH2-OE1 3.48Å; R366-E378 IonicContact NH2-OE2 3.67Å; R366-E378 PolarHBondContact NH2-OE2 2.81Å
367L98.1Very high98.6Very high78 Ų7845.6 Ų45.641%0.40825%0.248SC..Hα-helixtrans-59.4-33.2176.5-74.7169.2000112.3Y234 L243 S363 F364Y234-L367 HydrophobicContact CD1-CD1 4.49Å; Y234-L367 HydrophobicContact CE1-CD1 3.79Å; L243-L367 HydrophobicContact CD2-CD1 4.37Å; S363-L367 WeakPolarHBondContact O-CB 3.49Å; S363-L367 WeakPolarHBondContact O-CG 3.5Å; S363-L367 PolarHBondContact O-N 3.01Å; F364-L367 HydrophobicContact CD1-CD1 4.42Å; F364-L367 PolarHBondContact O-N 3.48Å
368L98.1Very high98.6Very high42 Ų4249.3 Ų49.322%0.2227%0.265CS..THydrogen-bonded Turntrans-90.34.7177.5-62.7177.1000113.7L243 R244 L247 F364 H365 R366L243-L368 HydrophobicContact CG-CD1 4.44Å; R244-L368 HydrophobicContact CB-CD1 4.14Å; R244-L368 HydrophobicContact CB-CD2 4.18Å; L247-L368 HydrophobicContact CD2-CD1 3.76Å; F364-L368 WeakPolarHBondContact O-CG 3.48Å; F364-L368 PolarHBondContact O-N 3.2Å; H365-L368 CarbonylContact O-C 3.58Å; H365-L368 PolarHBondContact O-N 2.86Å; R366-L368 PolarHBondContact O-N 3.34Å
369G97.9Very high98.6Very high57 Ų5755.8 Ų55.859%0.58829%0.29SS*.THydrogen-bonded Turntrans84.18.917600000115.6H365 R366 N371H365-G369 PolarHBondContact O-N 3.18Å; H365-G369 VanDerWaalsContact O-N 3.12Å; R366-G369 PolarHBondContact O-N 2.91Å; G369-N371 PolarHBondContact O-N 3.24Å
370N97.9Very high98.6Very high60 Ų6052.4 Ų52.432%0.32128%0.276SS..  trans-94.580.9178-173.3-4.6000111.7H365 E372 S373 A374H365-N370 HydrophobicContact CB-CB 4.28Å; H365-N370 PolarHBondContact ND1-ND2 2.91Å; H365-N370 PolarHBondContact O-N 3.33Å; N370-E372 VanDerWaalsContact C-N 3.31Å; N370-E372 PolarHBondContact O-N 3.14Å; N370-E372 PolarHBondContact OD1-N 2.92Å; N370-S373 VanDerWaalsContact ND2-CB 3.3Å; N370-S373 WeakPolarHBondContact ND2-CB 3.43Å; N370-S373 PolarHBondContact ND2-OG 2.69Å; N370-S373 PolarHBondContact OD1-N 3.17Å; N370-S373 VanDerWaalsContact OD1-N 3.16Å; N370-A374 WeakPolarHBondContact O-CB 3.45Å; N370-A374 PolarHBondContact O-N 3.48Å; N370-A374 VanDerWaalsContact O-N 3.1Å
371N98.1Very high98.6Very high105 Ų10552.1 Ų52.156%0.56128%0.276SS*.Hα-helixtrans-68.2-26.6-177.8-70.7-43.2000114.1G369 A375G369-N371 PolarHBondContact O-N 3.24Å; N371-A375 WeakPolarHBondContact O-CB 3.46Å; N371-A375 PolarHBondContact O-N 2.84Å
372E98.3Very high98.5Very high164 Ų16454.9 Ų54.977%0.76630%0.298SS*.Hα-helixtrans-69.9-51180-176177.7-179.400111.1N370 A374 A375 L376N370-E372 VanDerWaalsContact C-N 3.31Å; N370-E372 PolarHBondContact O-N 3.14Å; N370-E372 PolarHBondContact OD1-N 2.92Å; E372-A374 VanDerWaalsContact C-N 3.29Å; E372-A374 PolarHBondContact O-N 2.98Å; E372-A375 PolarHBondContact O-N 2.92Å; E372-L376 PolarHBondContact O-N 3.5Å; E372-L376 VanDerWaalsContact O-N 3.08Å
373S98.4Very high98.5Very high31 Ų3161.6 Ų61.622%0.21732%0.323CS..Hα-helixtrans-64.5-35.4174.4-64.80000111.6H365 N370 A375 L376 Y377H365-S373 VanDerWaalsContact CG-CB 3.46Å; H365-S373 WeakPolarHBondContact ND1-CB 3.33Å; N370-S373 VanDerWaalsContact ND2-CB 3.3Å; N370-S373 WeakPolarHBondContact ND2-CB 3.43Å; N370-S373 PolarHBondContact ND2-OG 2.69Å; N370-S373 PolarHBondContact OD1-N 3.17Å; N370-S373 VanDerWaalsContact OD1-N 3.16Å; S373-A375 PolarHBondContact O-N 2.63Å; S373-L376 VanDerWaalsContact O-CB 3.32Å; S373-L376 WeakPolarHBondContact O-CB 3.4Å; S373-L376 PolarHBondContact O-N 3.08Å; S373-L376 VanDerWaalsContact O-N 3.16Å; S373-Y377 VanDerWaalsContact O-CD2 3.23Å; S373-Y377 WeakPolarHBondContact O-CD2 3.35Å; S373-Y377 PolarHBondContact O-N 2.85Å
374A98.8Very high98.5Very high0 Ų059.4 Ų59.40%031%0.307CS..Hα-helixtrans-57-49.1173.100000111.7A362 H365 R366 N370 E372 L376 Y377 E378A362-A374 WeakPolarHBondContact O-CB 3.41Å; H365-A374 HydrophobicContact CB-CB 4.03Å; R366-A374 HydrophobicContact CB-CB 4.17Å; N370-A374 WeakPolarHBondContact O-CB 3.45Å; N370-A374 PolarHBondContact O-N 3.48Å; N370-A374 VanDerWaalsContact O-N 3.1Å; E372-A374 VanDerWaalsContact C-N 3.29Å; E372-A374 PolarHBondContact O-N 2.98Å; A374-L376 VanDerWaalsContact C-N 3.26Å; A374-L376 PolarHBondContact O-N 3.28Å; A374-Y377 PolarHBondContact O-N 3.09Å; A374-E378 WeakPolarHBondContact O-CG 3.33Å; A374-E378 PolarHBondContact O-N 3.22Å
375A98.8Very high98.5Very high35 Ų3560.5 Ų60.529%0.28931%0.313SS..Hα-helixtrans-65.2-26.5177.800000113.5N371 E372 S373 R379N371-A375 WeakPolarHBondContact O-CB 3.46Å; N371-A375 PolarHBondContact O-N 2.84Å; E372-A375 PolarHBondContact O-N 2.92Å; S373-A375 PolarHBondContact O-N 2.63Å; A375-R379 WeakPolarHBondContact O-CG 3.16Å; A375-R379 PolarHBondContact O-N 3.02Å; A375-R379 PolarHBondContact O-NE 2.74Å
376L98.7Very high98.4Very high86 Ų8665.7 Ų65.745%0.4534%0.337SS..Hα-helixtrans-63.3-51.8172.1-178.975.1000111.1E372 S373 A374 R379 A380E372-L376 PolarHBondContact O-N 3.5Å; E372-L376 VanDerWaalsContact O-N 3.08Å; S373-L376 VanDerWaalsContact O-CB 3.32Å; S373-L376 WeakPolarHBondContact O-CB 3.4Å; S373-L376 PolarHBondContact O-N 3.08Å; S373-L376 VanDerWaalsContact O-N 3.16Å; A374-L376 VanDerWaalsContact C-N 3.26Å; A374-L376 PolarHBondContact O-N 3.28Å; L376-R379 PolarHBondContact O-N 3.17Å; L376-A380 PolarHBondContact O-N 2.71Å
377Y98.8Very high98.4Very high15 Ų1560 Ų606%0.05932%0.316CS..Hα-helixtrans-73.4-30-177.9-71.2-71.1000113.1E251 Y254 E358 L361 H365 S373 A374 R379 A380 A381E251-Y377 HydrophobicContact CG-CE2 4.46Å; E251-Y377 VanDerWaalsContact CG-OH 3.26Å; E251-Y377 WeakPolarHBondContact CG-OH 3.47Å; E251-Y377 WeakPolarHBondContact OE1-CE2 3.46Å; E251-Y377 VanDerWaalsContact OE1-CZ 3.3Å; E251-Y377 PolarHBondContact OE1-OH 3.03Å; Y254-Y377 AromaticContact CD1-CE1 3.72Å; Y254-Y377 HydrophobicContact CD1-CE1 3.72Å; Y254-Y377 HydrophobicContact CE1-CD1 4.25Å; Y254-Y377 AromaticContact CE1-CE1 3.63Å; Y254-Y377 HydrophobicContact CE1-CE1 3.63Å; E358-Y377 WeakPolarHBondContact O-CB 3.16Å; L361-Y377 HydrophobicContact CB-CD1 3.91Å; L361-Y377 HydrophobicContact CB-CD2 3.88Å; L361-Y377 HydrophobicContact CB-CE1 4.18Å; L361-Y377 HydrophobicContact CB-CE2 4.16Å; L361-Y377 HydrophobicContact CB-CG 3.77Å; L361-Y377 HydrophobicContact CD1-CD1 3.84Å; L361-Y377 HydrophobicContact CD1-CE1 3.51Å; L361-Y377 HydrophobicContact CG-CE1 4.47Å; H365-Y377 AromaticContact CD2-CD2 3.75Å; H365-Y377 AromaticContact CD2-CE2 3.64Å; H365-Y377 AromaticContact NE2-CE2 3.63Å; S373-Y377 VanDerWaalsContact O-CD2 3.23Å; S373-Y377 WeakPolarHBondContact O-CD2 3.35Å; S373-Y377 PolarHBondContact O-N 2.85Å; A374-Y377 PolarHBondContact O-N 3.09Å; Y377-R379 VanDerWaalsContact C-N 3.31Å; Y377-R379 PolarHBondContact O-N 3.37Å; Y377-A380 WeakPolarHBondContact O-CB 3.16Å; Y377-A380 PolarHBondContact O-N 3.49Å; Y377-A380 VanDerWaalsContact O-N 3.12Å; Y377-A381 PolarHBondContact O-N 3.03Å
378E98.8Very high98.4Very high81 Ų8156.4 Ų56.438%0.37930%0.296SS..Hα-helixtrans-60.9-41.6170.2-73.6176.8154.700111.9A362 R366 A374 A380 A381 A382A362-E378 HydrophobicContact CB-CG 3.74Å; R366-E378 IonicContact CZ-OE1 3.42Å; R366-E378 IonicContact NH1-OE1 3.86Å; R366-E378 PolarHBondContact NH1-OE1 2.98Å; R366-E378 IonicContact NH2-OE1 2.63Å; R366-E378 PolarHBondContact NH2-OE1 3.48Å; R366-E378 IonicContact NH2-OE2 3.67Å; R366-E378 PolarHBondContact NH2-OE2 2.81Å; A374-E378 WeakPolarHBondContact O-CG 3.33Å; A374-E378 PolarHBondContact O-N 3.22Å; E378-A380 VanDerWaalsContact C-N 3.32Å; E378-A381 PolarHBondContact O-N 3.36Å; E378-A382 WeakPolarHBondContact O-CB 3.15Å; E378-A382 PolarHBondContact O-N 2.85Å
379R98.8Very high98.4Very high139 Ų13956.7 Ų56.753%0.52530%0.297SS..Hα-helixtrans-67.5-33.5173.8-71.7179-68.5-1681112.1A375 L376 Y377 R383A375-R379 WeakPolarHBondContact O-CG 3.16Å; A375-R379 PolarHBondContact O-N 3.02Å; A375-R379 PolarHBondContact O-NE 2.74Å; L376-R379 PolarHBondContact O-N 3.17Å; Y377-R379 VanDerWaalsContact C-N 3.31Å; Y377-R379 PolarHBondContact O-N 3.37Å; R379-R383 WeakPolarHBondContact O-CG 3.38Å; R379-R383 PolarHBondContact O-N 2.65Å; R379-R383 VanDerWaalsContact O-N 3.07Å
380A98.8Very high98.4Very high7 Ų755 Ų556%0.05828%0.277CS..Hα-helixtrans-64.2-50.8173.700000111.2E358 L376 Y377 E378 A382 R383 R384E358-A380 HydrophobicContact CB-CB 4.5Å; E358-A380 HydrophobicContact CG-CB 4.03Å; L376-A380 PolarHBondContact O-N 2.71Å; Y377-A380 WeakPolarHBondContact O-CB 3.16Å; Y377-A380 PolarHBondContact O-N 3.49Å; Y377-A380 VanDerWaalsContact O-N 3.12Å; E378-A380 VanDerWaalsContact C-N 3.32Å; A380-A382 VanDerWaalsContact C-N 3.32Å; A380-A382 PolarHBondContact O-N 3.47Å; A380-R383 PolarHBondContact O-N 3.27Å; A380-R383 VanDerWaalsContact O-N 3.15Å; A380-R384 PolarHBondContact O-N 3.23Å
381A98.8Very high98.4Very high5 Ų552.2 Ų52.24%0.04126%0.262CS..Hα-helixtrans-56.6-43.817600000112.4E358 K359 Y377 E378 R384 M385E358-A381 HydrophobicContact CB-CB 3.84Å; E358-A381 VanDerWaalsContact OE2-CA 3.23Å; E358-A381 WeakPolarHBondContact OE2-CA 3.47Å; E358-A381 PolarHBondContact OE2-N 2.75Å; K359-A381 HydrophobicContact CG-CB 3.96Å; Y377-A381 PolarHBondContact O-N 3.03Å; E378-A381 PolarHBondContact O-N 3.36Å; A381-R384 PolarHBondContact O-N 2.87Å; A381-M385 WeakPolarHBondContact O-CB 3.31Å; A381-M385 PolarHBondContact O-N 3.44Å
382A98.6Very high98.4Very high58 Ų5847.2 Ų47.248%0.47924%0.235SC..Hα-helixtrans-62.8-44.4177.200000112.4E378 A380 M385 Q386E378-A382 WeakPolarHBondContact O-CB 3.15Å; E378-A382 PolarHBondContact O-N 2.85Å; A380-A382 VanDerWaalsContact C-N 3.32Å; A380-A382 PolarHBondContact O-N 3.47Å; A382-M385 PolarHBondContact O-N 2.86Å; A382-Q386 PolarHBondContact O-N 3.19Å
383R98.3Very high98.4Very high144 Ų14440.7 Ų40.754%0.54320%0.204SC..Hα-helixtrans-64.3-41.3176.7-76-171.6-59.8-94.1-1.2112.2R379 A380 Q386 A387R379-R383 WeakPolarHBondContact O-CG 3.38Å; R379-R383 PolarHBondContact O-N 2.65Å; R379-R383 VanDerWaalsContact O-N 3.07Å; A380-R383 PolarHBondContact O-N 3.27Å; A380-R383 VanDerWaalsContact O-N 3.15Å; R383-Q386 PolarHBondContact O-N 3.23Å; R383-A387 WeakPolarHBondContact O-CB 3.49Å; R383-A387 PolarHBondContact O-N 3.05Å
384R98.8Very high98.4Very high6 Ų640 Ų402%0.02320%0.198CC..Hα-helixtrans-65.7-44.3177.9-174.2176.2-59-85.6-1111.6M258 L274 N275 N351 C355 E358 A380 A381 Q386 A387 M388M258-R384 PolarHBondContact SD-NH2 2.66Å; L274-R384 HydrophobicContact CD2-CG 4.16Å; N275-R384 PolarHBondContact OD1-NH1 2.93Å; N275-R384 PolarHBondContact OD1-NH2 2.97Å; N351-R384 WeakPolarHBondContact O-CD 3.4Å; N351-R384 PolarHBondContact OD1-NH1 2.87Å; C355-R384 HydrophobicContact CB-CG 4.26Å; C355-R384 VanDerWaalsContact N-CD 3.35Å; E358-R384 IonicContact OE1-CZ 3.24Å; E358-R384 VanDerWaalsContact OE1-CZ 3.23Å; E358-R384 IonicContact OE1-NE 2.74Å; E358-R384 PolarHBondContact OE1-NE 2.61Å; E358-R384 IonicContact OE1-NH2 3.45Å; E358-R384 PolarHBondContact OE1-NH2 3.12Å; E358-R384 WeakPolarHBondContact OE2-CB 3.41Å; E358-R384 WeakPolarHBondContact OE2-CD 3.31Å; E358-R384 IonicContact OE2-NE 2.79Å; E358-R384 PolarHBondContact OE2-NE 3.21Å; E358-R384 VanDerWaalsContact OE2-NE 3.07Å; A380-R384 PolarHBondContact O-N 3.23Å; A381-R384 PolarHBondContact O-N 2.87Å; R384-Q386 VanDerWaalsContact C-N 3.32Å; R384-Q386 PolarHBondContact O-N 3.05Å; R384-A387 WeakPolarHBondContact O-CB 3.49Å; R384-A387 PolarHBondContact O-N 3.44Å; R384-A387 VanDerWaalsContact O-N 3.13Å; R384-M388 HydrophobicContact CG-CG 4.31Å; R384-M388 HydrophobicContact CG-SD 4.15Å; R384-M388 WeakPolarHBondContact O-CG 3.43Å; R384-M388 PolarHBondContact O-N 3.12Å
385M98.2Very high98.3Very high28 Ų2843.3 Ų43.314%0.13823%0.225CC..Hα-helixtrans-57.8-45.8176-171-178-54.900111.2A381 A382 A387 M388 E389 S428A381-M385 WeakPolarHBondContact O-CB 3.31Å; A381-M385 PolarHBondContact O-N 3.44Å; A382-M385 PolarHBondContact O-N 2.86Å; M385-A387 VanDerWaalsContact C-N 3.35Å; M385-A387 PolarHBondContact O-N 3.3Å; M385-M388 PolarHBondContact O-N 3.22Å; M385-E389 WeakPolarHBondContact O-CG 3.47Å; M385-E389 PolarHBondContact O-N 2.97Å; M385-S428 PolarHBondContact SD-N 2.98Å; M385-S428 VanDerWaalsContact SD-N 3.44Å
386Q97.5Very high98.3Very high119 Ų11949.5 Ų49.556%0.55625%0.248SC*.Hα-helixtrans-59.4-43.6174.2-173.2-175.121.700112.3A382 R383 R384 E389 A390A382-Q386 PolarHBondContact O-N 3.19Å; R383-Q386 PolarHBondContact O-N 3.23Å; R384-Q386 VanDerWaalsContact C-N 3.32Å; R384-Q386 PolarHBondContact O-N 3.05Å; Q386-E389 PolarHBondContact O-N 2.72Å; Q386-A390 WeakPolarHBondContact O-CB 3.36Å; Q386-A390 PolarHBondContact O-N 3.24Å
387A98.4Very high98.2Very high1 Ų150 Ų501%0.00824%0.244CC..Hα-helixtrans-64.6-42.2177.500000112.7H272 L274 R383 R384 M385 E389 A390 L391H272-A387 HydrophobicContact CB-CB 3.75Å; L274-A387 HydrophobicContact CD1-CB 4.45Å; L274-A387 HydrophobicContact CD2-CB 3.66Å; L274-A387 HydrophobicContact CG-CB 3.93Å; R383-A387 WeakPolarHBondContact O-CB 3.49Å; R383-A387 PolarHBondContact O-N 3.05Å; R384-A387 WeakPolarHBondContact O-CB 3.49Å; R384-A387 PolarHBondContact O-N 3.44Å; R384-A387 VanDerWaalsContact O-N 3.13Å; M385-A387 VanDerWaalsContact C-N 3.35Å; M385-A387 PolarHBondContact O-N 3.3Å; A387-E389 VanDerWaalsContact C-N 3.33Å; A387-E389 PolarHBondContact O-N 2.86Å; A387-A390 PolarHBondContact O-N 3.24Å; A387-L391 WeakPolarHBondContact O-CB 3.48Å; A387-L391 PolarHBondContact O-N 2.88Å
388M98.5Very high98.2Very high1 Ų149.4 Ų49.41%0.00524%0.243CC..Hα-helixtrans-63.3-39.1175.5-70177.468.300111.6L274 N351 A352 C355 R384 M385 L392 W393 P421L274-M388 HydrophobicContact CD2-CG 3.94Å; N351-M388 VanDerWaalsContact C-SD 3.58Å; N351-M388 HydrophobicContact CB-CE 4.28Å; N351-M388 HydrophobicContact CB-CG 3.99Å; N351-M388 HydrophobicContact CB-SD 3.93Å; A352-M388 HydrophobicContact CB-CE 3.94Å; C355-M388 HydrophobicContact CB-SD 4.4Å; R384-M388 HydrophobicContact CG-CG 4.31Å; R384-M388 HydrophobicContact CG-SD 4.15Å; R384-M388 WeakPolarHBondContact O-CG 3.43Å; R384-M388 PolarHBondContact O-N 3.12Å; M385-M388 PolarHBondContact O-N 3.22Å; M388-L392 HydrophobicContact CB-CD1 4.29Å; M388-L392 HydrophobicContact CE-CD1 4.5Å; M388-L392 HydrophobicContact CG-CD1 4.03Å; M388-L392 CarbonylContact O-C 3.56Å; M388-L392 WeakPolarHBondContact O-CA 3.48Å; M388-L392 VanDerWaalsContact O-CB 3.25Å; M388-L392 WeakPolarHBondContact O-CB 3.46Å; M388-L392 PolarHBondContact O-N 2.99Å; M388-W393 PolarHBondContact O-N 3.16Å; M388-P421 HydrophobicContact CE-CB 4.27Å; M388-P421 HydrophobicContact CE-CG 3.78Å
389E97.4Very high98.2Very high49 Ų4945.6 Ų45.623%0.22923%0.225CC..Hα-helixtrans-69.8-34.6176.4-72.5176.8-167.400112.8M385 Q386 A387 W393 S428 M432M385-E389 WeakPolarHBondContact O-CG 3.47Å; M385-E389 PolarHBondContact O-N 2.97Å; Q386-E389 PolarHBondContact O-N 2.72Å; A387-E389 VanDerWaalsContact C-N 3.33Å; A387-E389 PolarHBondContact O-N 2.86Å; E389-W393 WeakPolarHBondContact O-CB 3.26Å; E389-S428 WeakPolarHBondContact OE1-CB 3.39Å; E389-S428 PolarHBondContact OE1-N 3.38Å; E389-S428 PolarHBondContact OE1-OG 3.47Å; E389-S428 PolarHBondContact OE2-OG 3.15Å; E389-M432 HydrophobicContact CG-CE 3.93Å
390A97.3Very high98.2Very high21 Ų2139 Ų3917%0.17420%0.2CC..Hα-helixtrans-70.8-45.8176.400000112.3Q386 A387 R410Q386-A390 WeakPolarHBondContact O-CB 3.36Å; Q386-A390 PolarHBondContact O-N 3.24Å; A387-A390 PolarHBondContact O-N 3.24Å; A390-R410 PolarHBondContact O-NH2 3.05Å; A390-R410 VanDerWaalsContact O-NH2 3.14Å
391L98.1Very high98.2Very high1 Ų138.6 Ų38.61%0.00520%0.197CC..Hα-helixtrans-95.8-40.1-169.8-74.2162.3000113.4V265 A267 H272 L274 L346 A387 Y403 R410V265-L391 HydrophobicContact CB-CD1 4.16Å; V265-L391 HydrophobicContact CG1-CD1 4.38Å; V265-L391 HydrophobicContact CG1-CD2 3.89Å; A267-L391 HydrophobicContact CB-CD2 3.52Å; A267-L391 HydrophobicContact CB-CG 4.02Å; H272-L391 HydrophobicContact CB-CD1 3.85Å; L274-L391 HydrophobicContact CD1-CB 4.09Å; L274-L391 HydrophobicContact CD1-CD1 3.61Å; L274-L391 HydrophobicContact CD1-CG 4.49Å; L274-L391 HydrophobicContact CG-CD1 4.29Å; L346-L391 HydrophobicContact CD1-CD1 4.28Å; A387-L391 WeakPolarHBondContact O-CB 3.48Å; A387-L391 PolarHBondContact O-N 2.88Å; L391-Y403 HydrophobicContact CD2-CD1 4.35Å; L391-Y403 HydrophobicContact CD2-CD2 4.1Å; L391-Y403 HydrophobicContact CD2-CE1 4.11Å; L391-Y403 HydrophobicContact CD2-CE2 3.85Å; L391-Y403 HydrophobicContact CD2-CG 4.33Å; L391-Y403 WeakPolarHBondContact O-CD2 3.39Å; L391-R410 WeakPolarHBondContact O-CG 3.33Å; L391-R410 PolarHBondContact O-NE 3.47Å
392L98.5Very high98.2Very high0 Ų038.6 Ų38.60%020%0.196CC..THydrogen-bonded Turntrans-105.2-28.9-166.2-47.5-177.4000113L274 L346 V348 N351 M388 W400 F401L274-L392 HydrophobicContact CD1-CD1 4.21Å; L274-L392 HydrophobicContact CD1-CD2 4.35Å; L274-L392 HydrophobicContact CD1-CG 4.19Å; L346-L392 HydrophobicContact CB-CD2 4.23Å; V348-L392 HydrophobicContact CG2-CB 4.26Å; V348-L392 HydrophobicContact CG2-CD1 4.17Å; N351-L392 HydrophobicContact CB-CD1 4.39Å; M388-L392 HydrophobicContact CB-CD1 4.29Å; M388-L392 HydrophobicContact CE-CD1 4.5Å; M388-L392 HydrophobicContact CG-CD1 4.03Å; M388-L392 CarbonylContact O-C 3.56Å; M388-L392 WeakPolarHBondContact O-CA 3.48Å; M388-L392 VanDerWaalsContact O-CB 3.25Å; M388-L392 WeakPolarHBondContact O-CB 3.46Å; M388-L392 PolarHBondContact O-N 2.99Å; L392-W400 HydrophobicContact CB-CB 4.47Å; L392-W400 CarbonylContact O-C 3.55Å; L392-W400 VanDerWaalsContact O-CA 3.27Å; L392-W400 WeakPolarHBondContact O-CA 3.37Å; L392-F401 WeakPolarHBondContact CA-O 3.03Å; L392-F401 WeakPolarHBondContact CB-O 3.15Å; L392-F401 PolarHBondContact O-N 3.07Å
393W98.4Very high98.1Very high28 Ų2837 Ų3711%0.10618%0.178CC..EExtended strand (participates in β ladder)trans-77.6134.1-179.3176.5-111000112.8M388 E389 G398 A399 W400 R410 M432 K435M388-W393 PolarHBondContact O-N 3.16Å; E389-W393 WeakPolarHBondContact O-CB 3.26Å; W393-G398 WeakPolarHBondContact CH2-O 3.41Å; W393-G398 WeakPolarHBondContact CZ3-O 3.41Å; W393-A399 VanDerWaalsContact CE3-C 3.45Å; W393-A399 VanDerWaalsContact CZ3-CA 3.48Å; W393-W400 HydrophobicContact CD2-CZ2 4.46Å; W393-W400 AromaticContact CE3-CD2 3.5Å; W393-W400 HydrophobicContact CE3-CD2 3.5Å; W393-W400 AromaticContact CE3-CE2 3.37Å; W393-W400 AromaticContact CE3-CE3 3.89Å; W393-W400 HydrophobicContact CE3-CE3 3.89Å; W393-W400 AromaticContact CE3-CG 3.97Å; W393-W400 HydrophobicContact CE3-CG 3.97Å; W393-W400 AromaticContact CE3-CH2 4Å; W393-W400 HydrophobicContact CE3-CH2 4Å; W393-W400 AromaticContact CE3-CZ2 3.62Å; W393-W400 HydrophobicContact CE3-CZ2 3.62Å; W393-W400 HydrophobicContact CE3-CZ3 4.13Å; W393-W400 AromaticContact CE3-NE1 3.78Å; W393-W400 HydrophobicContact CH2-CH2 4.41Å; W393-W400 AromaticContact CZ3-CD2 3.86Å; W393-W400 HydrophobicContact CZ3-CD2 3.86Å; W393-W400 AromaticContact CZ3-CE2 3.85Å; W393-W400 AromaticContact CZ3-CE3 3.74Å; W393-W400 HydrophobicContact CZ3-CE3 3.74Å; W393-W400 AromaticContact CZ3-CH2 3.59Å; W393-W400 HydrophobicContact CZ3-CH2 3.59Å; W393-W400 AromaticContact CZ3-CZ2 3.71Å; W393-W400 HydrophobicContact CZ3-CZ2 3.71Å; W393-W400 AromaticContact CZ3-CZ3 3.61Å; W393-W400 HydrophobicContact CZ3-CZ3 3.61Å; W393-R410 PolarHBondContact O-NE 2.79Å; W393-R410 PolarHBondContact O-NH1 2.79Å; W393-R410 PolarHBondContact O-NH2 2.84Å; W393-M432 HydrophobicContact CB-CE 4.36Å; W393-M432 HydrophobicContact CD2-CE 3.33Å; W393-M432 VanDerWaalsContact CE2-CE 3.44Å; W393-M432 HydrophobicContact CE3-CE 3.71Å; W393-M432 HydrophobicContact CG-CE 3.64Å; W393-M432 HydrophobicContact CH2-CB 3.92Å; W393-M432 HydrophobicContact CH2-CE 4.2Å; W393-M432 HydrophobicContact CH2-CG 4.22Å; W393-M432 HydrophobicContact CZ2-CB 4.19Å; W393-M432 HydrophobicContact CZ2-CE 3.9Å; W393-M432 HydrophobicContact CZ2-CG 3.97Å; W393-M432 HydrophobicContact CZ3-CB 4.41Å; W393-M432 HydrophobicContact CZ3-CE 4.11Å; W393-K435 HydrophobicContact CH2-CB 4.04Å; W393-K435 HydrophobicContact CH2-CD 4.45Å; W393-K435 HydrophobicContact CZ2-CB 4.49Å; W393-K435 HydrophobicContact CZ2-CD 4.09Å
394D98.4Very high98Very high17 Ų1730.3 Ų30.39%0.09115%0.153CC..EExtended strand (participates in β ladder)trans-116.5109.6169.6-167.2-105.9000110.2E396 R397 G398 A399 F401 R410 F412D394-E396 VanDerWaalsContact C-N 3.31Å; D394-E396 PolarHBondContact O-N 3.14Å; D394-R397 HydrophobicContact CB-CB 4.38Å; D394-R397 PolarHBondContact O-N 3.18Å; D394-R397 WeakPolarHBondContact OD1-CB 3.44Å; D394-R397 WeakPolarHBondContact OD1-CD 3.35Å; D394-R397 WeakPolarHBondContact OD1-CG 3.28Å; D394-R397 IonicContact OD1-CZ 3.83Å; D394-R397 PolarHBondContact OD1-N 2.75Å; D394-R397 IonicContact OD1-NH1 2.79Å; D394-R397 PolarHBondContact OD1-NH1 2.97Å; D394-G398 WeakPolarHBondContact O-CA 3.34Å; D394-G398 PolarHBondContact O-N 3.09Å; D394-A399 PolarHBondContact N-O 2.9Å; D394-A399 PolarHBondContact O-N 2.76Å; D394-F401 HydrophobicContact CB-CD2 3.77Å; D394-F401 HydrophobicContact CB-CE2 3.78Å; D394-R410 IonicContact OD2-NH1 2.7Å; D394-R410 PolarHBondContact OD2-NH1 3.3Å; D394-F412 HydrophobicContact CB-CE1 4.15Å
395A97.4Very high97.9Very high68 Ų6831.2 Ų31.256%0.56216%0.158SC*.THydrogen-bonded Turntrans-69.5-26.4-174.400000113.8
396E97.4Very high97.7Very high165 Ų16534.2 Ų34.277%0.77117%0.174SC*.THydrogen-bonded Turntrans-70.6-48177.7-177.5-174.2-157.200110.7D394D394-E396 VanDerWaalsContact C-N 3.31Å; D394-E396 PolarHBondContact O-N 3.14Å
397R97.9Very high97.5Very high96 Ų9631.1 Ų31.136%0.36216%0.164SC..THydrogen-bonded Turntrans-78.4-24.3177.2-72.4162-17564.88.5113.1D394 F401 Y439D394-R397 HydrophobicContact CB-CB 4.38Å; D394-R397 PolarHBondContact O-N 3.18Å; D394-R397 WeakPolarHBondContact OD1-CB 3.44Å; D394-R397 WeakPolarHBondContact OD1-CD 3.35Å; D394-R397 WeakPolarHBondContact OD1-CG 3.28Å; D394-R397 IonicContact OD1-CZ 3.83Å; D394-R397 PolarHBondContact OD1-N 2.75Å; D394-R397 IonicContact OD1-NH1 2.79Å; D394-R397 PolarHBondContact OD1-NH1 2.97Å; R397-F401 HydrophobicContact CB-CE2 3.82Å; R397-F401 HydrophobicContact CB-CZ 3.94Å; R397-F401 HydrophobicContact CG-CE2 4.47Å; R397-F401 HydrophobicContact CG-CZ 4.41Å; R397-Y439 WeakPolarHBondContact O-CB 3.21Å
398G98.2Very high97.3Very high4 Ų436 Ų364%0.04119%0.189CC..THydrogen-bonded Turntrans74.631.1-179.600000113.8W393 D394 K435 A436W393-G398 WeakPolarHBondContact CH2-O 3.41Å; W393-G398 WeakPolarHBondContact CZ3-O 3.41Å; D394-G398 WeakPolarHBondContact O-CA 3.34Å; D394-G398 PolarHBondContact O-N 3.09Å; G398-K435 CarbonylContact O-C 3.56Å; G398-K435 VanDerWaalsContact O-C 3.22Å; G398-A436 WeakPolarHBondContact O-CA 3.33Å; G398-A436 PolarHBondContact O-N 3.3Å
399A98.6Very high97.1Very high0 Ų038.5 Ų38.50%021%0.207CC..EExtended strand (participates in β ladder)trans-147.1169.2179.800000112.4W393 D394 F401 L419 Y439W393-A399 VanDerWaalsContact CE3-C 3.45Å; W393-A399 VanDerWaalsContact CZ3-CA 3.48Å; D394-A399 PolarHBondContact N-O 2.9Å; D394-A399 PolarHBondContact O-N 2.76Å; A399-F401 HydrophobicContact CB-CE2 3.83Å; A399-F401 HydrophobicContact CB-CZ 3.87Å; A399-F401 WeakPolarHBondContact O-CD2 3.42Å; A399-F401 WeakPolarHBondContact O-CE2 3.11Å; A399-L419 HydrophobicContact CB-CD2 4.43Å; A399-Y439 HydrophobicContact CB-CD1 3.44Å; A399-Y439 VanDerWaalsContact CB-CD1 3.44Å; A399-Y439 HydrophobicContact CB-CD2 3.92Å; A399-Y439 HydrophobicContact CB-CE1 3.73Å; A399-Y439 HydrophobicContact CB-CE2 4.21Å; A399-Y439 HydrophobicContact CB-CG 3.51Å
400W98.8Very high97Very high0 Ų039.5 Ų39.50%021%0.209CC..EExtended strand (participates in β ladder)trans-95.5142.4173.3-62.7-98000110.9V348 L392 W393 N418 P421 V422 F427 M432 A436V348-W400 HydrophobicContact CB-CB 4.46Å; V348-W400 HydrophobicContact CG1-CB 3.61Å; V348-W400 HydrophobicContact CG1-CG 4.44Å; V348-W400 HydrophobicContact CG2-CB 3.91Å; L392-W400 HydrophobicContact CB-CB 4.47Å; L392-W400 CarbonylContact O-C 3.55Å; L392-W400 VanDerWaalsContact O-CA 3.27Å; L392-W400 WeakPolarHBondContact O-CA 3.37Å; W393-W400 HydrophobicContact CD2-CZ2 4.46Å; W393-W400 AromaticContact CE3-CD2 3.5Å; W393-W400 HydrophobicContact CE3-CD2 3.5Å; W393-W400 AromaticContact CE3-CE2 3.37Å; W393-W400 AromaticContact CE3-CE3 3.89Å; W393-W400 HydrophobicContact CE3-CE3 3.89Å; W393-W400 AromaticContact CE3-CG 3.97Å; W393-W400 HydrophobicContact CE3-CG 3.97Å; W393-W400 AromaticContact CE3-CH2 4Å; W393-W400 HydrophobicContact CE3-CH2 4Å; W393-W400 AromaticContact CE3-CZ2 3.62Å; W393-W400 HydrophobicContact CE3-CZ2 3.62Å; W393-W400 HydrophobicContact CE3-CZ3 4.13Å; W393-W400 AromaticContact CE3-NE1 3.78Å; W393-W400 HydrophobicContact CH2-CH2 4.41Å; W393-W400 AromaticContact CZ3-CD2 3.86Å; W393-W400 HydrophobicContact CZ3-CD2 3.86Å; W393-W400 AromaticContact CZ3-CE2 3.85Å; W393-W400 AromaticContact CZ3-CE3 3.74Å; W393-W400 HydrophobicContact CZ3-CE3 3.74Å; W393-W400 AromaticContact CZ3-CH2 3.59Å; W393-W400 HydrophobicContact CZ3-CH2 3.59Å; W393-W400 AromaticContact CZ3-CZ2 3.71Å; W393-W400 HydrophobicContact CZ3-CZ2 3.71Å; W393-W400 AromaticContact CZ3-CZ3 3.61Å; W393-W400 HydrophobicContact CZ3-CZ3 3.61Å; W400-N418 WeakPolarHBondContact O-CA 3.27Å; W400-N418 WeakPolarHBondContact O-CB 3.36Å; W400-N418 VanDerWaalsContact O-CG 3.31Å; W400-N418 PolarHBondContact O-ND2 3.02Å; W400-P421 HydrophobicContact CB-CG 4.07Å; W400-P421 HydrophobicContact CD2-CB 3.72Å; W400-P421 HydrophobicContact CD2-CG 3.52Å; W400-P421 HydrophobicContact CE3-CB 3.82Å; W400-P421 HydrophobicContact CE3-CG 3.79Å; W400-P421 HydrophobicContact CG-CB 4.32Å; W400-P421 HydrophobicContact CG-CG 3.65Å; W400-P421 HydrophobicContact CH2-CB 4.13Å; W400-P421 HydrophobicContact CZ2-CB 4.02Å; W400-P421 HydrophobicContact CZ3-CB 4.02Å; W400-P421 HydrophobicContact CZ3-CG 4.47Å; W400-V422 HydrophobicContact CZ3-CG2 3.94Å; W400-F427 HydrophobicContact CH2-CB 3.97Å; W400-F427 HydrophobicContact CH2-CD1 4.21Å; W400-F427 HydrophobicContact CH2-CG 4.23Å; W400-F427 HydrophobicContact CZ2-CB 3.58Å; W400-F427 HydrophobicContact CZ2-CG 4.33Å; W400-M432 HydrophobicContact CH2-CB 4.02Å; W400-M432 HydrophobicContact CH2-CE 4.36Å; W400-M432 HydrophobicContact CZ2-CB 4.26Å; W400-M432 HydrophobicContact CZ2-CE 3.51Å; W400-A436 HydrophobicContact CZ3-CB 3.89Å
401F98.7Very high96.7Very high0 Ų040 Ų400%021%0.207CC..  trans-133.9144.4-176.3-63.9-79.9000109.7V348 L392 D394 R397 A399 R410 H411 F412 N418 Y439V348-F401 WeakPolarHBondContact CG2-O 3.49Å; L392-F401 WeakPolarHBondContact CA-O 3.03Å; L392-F401 WeakPolarHBondContact CB-O 3.15Å; L392-F401 PolarHBondContact O-N 3.07Å; D394-F401 HydrophobicContact CB-CD2 3.77Å; D394-F401 HydrophobicContact CB-CE2 3.78Å; R397-F401 HydrophobicContact CB-CE2 3.82Å; R397-F401 HydrophobicContact CB-CZ 3.94Å; R397-F401 HydrophobicContact CG-CE2 4.47Å; R397-F401 HydrophobicContact CG-CZ 4.41Å; A399-F401 HydrophobicContact CB-CE2 3.83Å; A399-F401 HydrophobicContact CB-CZ 3.87Å; A399-F401 WeakPolarHBondContact O-CD2 3.42Å; A399-F401 WeakPolarHBondContact O-CE2 3.11Å; F401-R410 HydrophobicContact CB-CB 3.97Å; F401-R410 HydrophobicContact CB-CG 4.41Å; F401-H411 WeakPolarHBondContact CB-O 3.46Å; F401-H411 WeakPolarHBondContact CD1-O 3.43Å; F401-F412 HydrophobicContact CD1-CD1 4.16Å; F401-F412 AromaticContact CD2-CD1 3.91Å; F401-F412 HydrophobicContact CD2-CD1 3.91Å; F401-F412 HydrophobicContact CD2-CE1 4.22Å; F401-F412 HydrophobicContact CE1-CD1 4.33Å; F401-F412 HydrophobicContact CE2-CD1 4.12Å; F401-F412 AromaticContact CG-CD1 3.93Å; F401-F412 HydrophobicContact CG-CD1 3.93Å; F401-F412 HydrophobicContact CZ-CD1 4.31Å; F401-N418 WeakPolarHBondContact CD1-ND2 3.48Å; F401-Y439 HydrophobicContact CE1-CE2 4.17Å; F401-Y439 AromaticContact CE1-CZ 3.94Å; F401-Y439 WeakPolarHBondContact CE1-OH 3.38Å; F401-Y439 HydrophobicContact CZ-CD2 4.44Å; F401-Y439 AromaticContact CZ-CE2 3.73Å; F401-Y439 HydrophobicContact CZ-CE2 3.73Å; F401-Y439 AromaticContact CZ-CZ 3.88Å
402D98.4Very high96.6Very high4 Ų444.2 Ų44.22%0.02123%0.226CC..  trans-61.7146.4175.3-61.3-31.3000110R324 I345 L346 P347 V348 R410 H411R324-D402 WeakPolarHBondContact CG-OD2 3.47Å; R324-D402 IonicContact CZ-OD1 2.64Å; R324-D402 IonicContact CZ-OD2 3.1Å; R324-D402 IonicContact NE-OD1 2.85Å; R324-D402 IonicContact NE-OD2 2.84Å; R324-D402 PolarHBondContact NE-OD2 3.26Å; R324-D402 IonicContact NH2-OD1 3.75Å; R324-D402 PolarHBondContact NH2-OD1 3.17Å; R324-D402 IonicContact NH2-OD2 3.37Å; R324-D402 PolarHBondContact NH2-OD2 3.13Å; I345-D402 HydrophobicContact CG2-CB 3.64Å; L346-D402 WeakPolarHBondContact O-CA 3.39Å; P347-D402 VanDerWaalsContact CA-OD1 3.31Å; P347-D402 WeakPolarHBondContact CA-OD1 3.33Å; V348-D402 WeakPolarHBondContact CG2-OD1 3.49Å; V348-D402 PolarHBondContact N-OD1 3.44Å; D402-R410 WeakPolarHBondContact O-CA 3.31Å; D402-H411 PolarHBondContact O-N 3.45Å
403Y97.8Very high96.4Very high24 Ų2446 Ų469%0.09424%0.24CC..EExtended strand (participates in β ladder)trans-106.6122.1-179.9-172-88.2000110.5V265 I345 L346 L391 L405 N408 R410V265-Y403 HydrophobicContact CG1-CE1 4.26Å; I345-Y403 WeakPolarHBondContact CA-O 3.15Å; L346-Y403 HydrophobicContact CD1-CD1 4.13Å; L346-Y403 PolarHBondContact N-O 3.07Å; L346-Y403 PolarHBondContact O-N 2.91Å; L391-Y403 HydrophobicContact CD2-CD1 4.35Å; L391-Y403 HydrophobicContact CD2-CD2 4.1Å; L391-Y403 HydrophobicContact CD2-CE1 4.11Å; L391-Y403 HydrophobicContact CD2-CE2 3.85Å; L391-Y403 HydrophobicContact CD2-CG 4.33Å; L391-Y403 WeakPolarHBondContact O-CD2 3.39Å; Y403-L405 HydrophobicContact CD1-CD2 4.18Å; Y403-L405 HydrophobicContact CE1-CD2 4.36Å; Y403-N408 VanDerWaalsContact CZ-C 3.42Å; Y403-N408 VanDerWaalsContact OH-C 3.27Å; Y403-N408 VanDerWaalsContact OH-CA 3.27Å; Y403-N408 WeakPolarHBondContact OH-CA 3.33Å; Y403-N408 WeakPolarHBondContact OH-CB 3.14Å; Y403-N408 PolarHBondContact OH-O 2.83Å; Y403-R410 HydrophobicContact CD2-CG 4.13Å
404N96.2Very high96.4Very high4 Ų445.4 Ų45.42%0.02124%0.239CC..EExtended strand (participates in β ladder)trans-84.7118178.4-178.9-16.7000109.6I327 G331 L406 T407 N408 S409I327-N404 WeakPolarHBondContact CD1-ND2 3.34Å; G331-N404 PolarHBondContact O-ND2 3.41Å; G331-N404 VanDerWaalsContact O-ND2 3.15Å; N404-L406 VanDerWaalsContact C-N 3.32Å; N404-L406 VanDerWaalsContact OD1-CB 3.31Å; N404-L406 WeakPolarHBondContact OD1-CB 3.33Å; N404-L406 PolarHBondContact OD1-N 3.33Å; N404-T407 WeakPolarHBondContact CB-OG1 3.36Å; N404-T407 VanDerWaalsContact CG-OG1 3.29Å; N404-T407 PolarHBondContact ND2-OG1 3.03Å; N404-T407 PolarHBondContact OD1-N 3.27Å; N404-N408 VanDerWaalsContact O-CA 3.26Å; N404-N408 WeakPolarHBondContact O-CA 3.49Å; N404-N408 PolarHBondContact O-N 2.81Å; N404-S409 PolarHBondContact N-O 3.16Å; N404-S409 PolarHBondContact O-N 2.6Å
405L95.9Very high96.4Very high25 Ų2544.8 Ų44.813%0.13124%0.235CC..THydrogen-bonded Turntrans-74-21.2-178.3-64.2172000113.1I263 V265 Q344 L346 Y403I263-L405 HydrophobicContact CD1-CD1 4.14Å; V265-L405 HydrophobicContact CG2-CD2 3.74Å; Q344-L405 VanDerWaalsContact O-CB 3.32Å; Q344-L405 WeakPolarHBondContact O-CB 3.45Å; Q344-L405 WeakPolarHBondContact O-CG 3.13Å; Q344-L405 PolarHBondContact O-N 3.27Å; L346-L405 HydrophobicContact CD1-CD2 4.06Å; L346-L405 HydrophobicContact CD2-CD1 4.05Å; L346-L405 HydrophobicContact CD2-CD2 4.15Å; L346-L405 HydrophobicContact CD2-CG 4.37Å; L346-L405 HydrophobicContact CG-CD1 4.43Å; L346-L405 HydrophobicContact CG-CD2 3.9Å; L346-L405 HydrophobicContact CG-CG 4.21Å; Y403-L405 HydrophobicContact CD1-CD2 4.18Å; Y403-L405 HydrophobicContact CE1-CD2 4.36Å
406L93.9Very high96.4Very high92 Ų9242 Ų4248%0.48221%0.213SC..THydrogen-bonded Turntrans-75.4-42.4177.4-60.4172.5000111.2I327 Q344 N404I327-L406 HydrophobicContact CD1-CD1 4.41Å; I327-L406 HydrophobicContact CG2-CD1 4.09Å; Q344-L406 HydrophobicContact CB-CD1 4.12Å; Q344-L406 HydrophobicContact CB-CD2 4.39Å; Q344-L406 HydrophobicContact CB-CG 3.9Å; Q344-L406 HydrophobicContact CG-CD1 4.17Å; Q344-L406 HydrophobicContact CG-CD2 4.04Å; Q344-L406 HydrophobicContact CG-CG 4.05Å; N404-L406 VanDerWaalsContact C-N 3.32Å; N404-L406 VanDerWaalsContact OD1-CB 3.31Å; N404-L406 WeakPolarHBondContact OD1-CB 3.33Å; N404-L406 PolarHBondContact OD1-N 3.33Å
407T93.4Very high96.5Very high54 Ų5434.3 Ų34.333%0.33118%0.177SC..THydrogen-bonded Turntrans-97.5-11.3-177.358.60000113.5G331 N404 S409G331-T407 WeakPolarHBondContact O-CG2 3.46Å; N404-T407 WeakPolarHBondContact CB-OG1 3.36Å; N404-T407 VanDerWaalsContact CG-OG1 3.29Å; N404-T407 PolarHBondContact ND2-OG1 3.03Å; N404-T407 PolarHBondContact OD1-N 3.27Å; T407-S409 VanDerWaalsContact C-N 3.29Å; T407-S409 WeakPolarHBondContact CB-OG 3.47Å; T407-S409 PolarHBondContact O-N 3.03Å; T407-S409 PolarHBondContact OG1-OG 3.43Å
408N94.1Very high96.5Very high102 Ų10229.8 Ų29.855%0.54516%0.16SC..THydrogen-bonded Turntrans53.545.9-171.4-67.8-60.5000112.3Y403 N404Y403-N408 VanDerWaalsContact CZ-C 3.42Å; Y403-N408 VanDerWaalsContact OH-C 3.27Å; Y403-N408 VanDerWaalsContact OH-CA 3.27Å; Y403-N408 WeakPolarHBondContact OH-CA 3.33Å; Y403-N408 WeakPolarHBondContact OH-CB 3.14Å; Y403-N408 PolarHBondContact OH-O 2.83Å; N404-N408 VanDerWaalsContact O-CA 3.26Å; N404-N408 WeakPolarHBondContact O-CA 3.49Å; N404-N408 PolarHBondContact O-N 2.81Å
409S93.8Very high96.5Very high54 Ų5430 Ų3038%0.37816%0.16SC..EExtended strand (participates in β ladder)trans-144.4159.2-177.766.30000112.4N404 T407N404-S409 PolarHBondContact N-O 3.16Å; N404-S409 PolarHBondContact O-N 2.6Å; T407-S409 VanDerWaalsContact C-N 3.29Å; T407-S409 WeakPolarHBondContact CB-OG 3.47Å; T407-S409 PolarHBondContact O-N 3.03Å; T407-S409 PolarHBondContact OG1-OG 3.43Å
410R95Very high96.5Very high71 Ų7130.2 Ų30.227%0.26816%0.162SC..EExtended strand (participates in β ladder)trans-79.7145.2174.5-66.5173.1-154.8125.23.7110.9A390 L391 W393 D394 F401 D402 Y403 F412A390-R410 PolarHBondContact O-NH2 3.05Å; A390-R410 VanDerWaalsContact O-NH2 3.14Å; L391-R410 WeakPolarHBondContact O-CG 3.33Å; L391-R410 PolarHBondContact O-NE 3.47Å; W393-R410 PolarHBondContact O-NE 2.79Å; W393-R410 PolarHBondContact O-NH1 2.79Å; W393-R410 PolarHBondContact O-NH2 2.84Å; D394-R410 IonicContact OD2-NH1 2.7Å; D394-R410 PolarHBondContact OD2-NH1 3.3Å; F401-R410 HydrophobicContact CB-CB 3.97Å; F401-R410 HydrophobicContact CB-CG 4.41Å; D402-R410 WeakPolarHBondContact O-CA 3.31Å; Y403-R410 HydrophobicContact CD2-CG 4.13Å; R410-F412 HydrophobicContact CB-CD1 4.3Å; R410-F412 HydrophobicContact CB-CE1 3.75Å; R410-F412 HydrophobicContact CB-CZ 4.09Å
411H91.6Very high96.5Very high31 Ų3130.2 Ų30.214%0.14416%0.162CC..  trans-95.6111.8172.3177.9-142.6000110.9N333 F401 D402 A413 Y415N333-H411 WeakPolarHBondContact CB-CE1 3.34Å; N333-H411 WeakPolarHBondContact CB-NE2 3.46Å; N333-H411 VanDerWaalsContact CG-CE1 3.43Å; N333-H411 PolarHBondContact ND2-CE1 2.98Å; N333-H411 PolarHBondContact ND2-ND1 2.62Å; F401-H411 WeakPolarHBondContact CB-O 3.46Å; F401-H411 WeakPolarHBondContact CD1-O 3.43Å; D402-H411 PolarHBondContact O-N 3.45Å; H411-A413 VanDerWaalsContact CE1-CB 3.41Å; H411-A413 WeakPolarHBondContact CE1-CB 3.4Å; H411-A413 WeakPolarHBondContact NE2-CB 3.27Å; H411-A413 PolarHBondContact O-N 3.35Å; H411-Y415 AromaticContact CE1-CE2 3.53Å; H411-Y415 AromaticContact ND1-CE2 3.73Å
412F95.4Very high96.5Very high89 Ų8930.6 Ų30.639%0.3916%0.164SC..  trans-87.27.8-170.6-60.3-54.7000116.1D394 F401 R410D394-F412 HydrophobicContact CB-CE1 4.15Å; F401-F412 HydrophobicContact CD1-CD1 4.16Å; F401-F412 AromaticContact CD2-CD1 3.91Å; F401-F412 HydrophobicContact CD2-CD1 3.91Å; F401-F412 HydrophobicContact CD2-CE1 4.22Å; F401-F412 HydrophobicContact CE1-CD1 4.33Å; F401-F412 HydrophobicContact CE2-CD1 4.12Å; F401-F412 AromaticContact CG-CD1 3.93Å; F401-F412 HydrophobicContact CG-CD1 3.93Å; F401-F412 HydrophobicContact CZ-CD1 4.31Å; R410-F412 HydrophobicContact CB-CD1 4.3Å; R410-F412 HydrophobicContact CB-CE1 3.75Å; R410-F412 HydrophobicContact CB-CZ 4.09Å
413A95.3Very high96.5Very high37 Ų3730.5 Ų30.531%0.30616%0.163SC..SBendtrans-70.2150.5173.800000111H411 Y415 N418H411-A413 VanDerWaalsContact CE1-CB 3.41Å; H411-A413 WeakPolarHBondContact CE1-CB 3.4Å; H411-A413 WeakPolarHBondContact NE2-CB 3.27Å; H411-A413 PolarHBondContact O-N 3.35Å; A413-Y415 HydrophobicContact CB-CE2 3.88Å; A413-Y415 PolarHBondContact O-N 3.44Å; A413-N418 PolarHBondContact O-OD1 3.42Å
414F98.1Very high96.6Very high16 Ų1629.6 Ų29.67%0.0716%0.16CC..  trans-72.4125.6176.3178.9-88.1000111N418 Y439 L440 S443 A445 V452 S455 L456F414-N418 WeakPolarHBondContact CA-OD1 3.45Å; F414-Y439 AromaticContact CD2-CE1 3.79Å; F414-Y439 HydrophobicContact CD2-CE1 3.79Å; F414-Y439 AromaticContact CD2-CZ 3.9Å; F414-Y439 HydrophobicContact CE2-CE1 4.08Å; F414-L440 HydrophobicContact CE2-CD1 3.95Å; F414-L440 HydrophobicContact CZ-CD1 4.05Å; F414-S443 WeakPolarHBondContact CD2-OG 3.36Å; F414-S443 WeakPolarHBondContact CE2-OG 3.23Å; F414-A445 HydrophobicContact CD1-CB 3.88Å; F414-A445 HydrophobicContact CD2-CB 4.2Å; F414-A445 HydrophobicContact CE1-CB 3.31Å; F414-A445 HydrophobicContact CE2-CB 3.68Å; F414-A445 HydrophobicContact CG-CB 4.3Å; F414-A445 HydrophobicContact CZ-CB 3.2Å; F414-V452 HydrophobicContact CE1-CG1 4.26Å; F414-V452 HydrophobicContact CZ-CG1 4.04Å; F414-S455 WeakPolarHBondContact O-CA 3.21Å; F414-L456 HydrophobicContact CB-CD1 3.88Å; F414-L456 HydrophobicContact CB-CG 4.18Å; F414-L456 HydrophobicContact CD1-CD1 4.25Å; F414-L456 HydrophobicContact CD1-CG 3.91Å; F414-L456 HydrophobicContact CG-CD1 4.15Å; F414-L456 HydrophobicContact CG-CG 4.29Å
415Y98.4Very high96.6Very high4 Ų434 Ų342%0.01618%0.181CC..BIsolated β-bridgetrans-132.7145.6160.7-62.8-83.2000108.7W319 S323 R324 H411 A413 S417 N418 T454 S455W319-Y415 HydrophobicContact CZ3-CD1 4.06Å; S323-Y415 VanDerWaalsContact C-OH 3.31Å; S323-Y415 PolarHBondContact OG-OH 2.92Å; S323-Y415 VanDerWaalsContact OG-OH 3.1Å; R324-Y415 VanDerWaalsContact CA-CZ 3.44Å; R324-Y415 VanDerWaalsContact CA-OH 3.28Å; R324-Y415 WeakPolarHBondContact CA-OH 3.44Å; R324-Y415 HydrophobicContact CB-CD1 4.02Å; R324-Y415 HydrophobicContact CB-CE1 3.55Å; R324-Y415 HydrophobicContact CB-CE2 4.18Å; R324-Y415 HydrophobicContact CG-CD1 4.17Å; R324-Y415 HydrophobicContact CG-CD2 4.11Å; R324-Y415 HydrophobicContact CG-CE1 4.09Å; R324-Y415 HydrophobicContact CG-CE2 4.03Å; R324-Y415 HydrophobicContact CG-CG 4.19Å; R324-Y415 PolarHBondContact N-OH 3.43Å; H411-Y415 AromaticContact CE1-CE2 3.53Å; H411-Y415 AromaticContact ND1-CE2 3.73Å; A413-Y415 HydrophobicContact CB-CE2 3.88Å; A413-Y415 PolarHBondContact O-N 3.44Å; Y415-S417 WeakPolarHBondContact CB-OG 3.46Å; Y415-S417 PolarHBondContact O-N 3.18Å; Y415-N418 PolarHBondContact N-OD1 3.1Å; Y415-N418 VanDerWaalsContact O-CB 3.24Å; Y415-N418 WeakPolarHBondContact O-CB 3.42Å; Y415-N418 PolarHBondContact O-N 3.49Å; Y415-N418 PolarHBondContact O-OD1 2.65Å; Y415-T454 VanDerWaalsContact CA-O 3.3Å; Y415-T454 WeakPolarHBondContact CA-O 3.44Å; Y415-S455 VanDerWaalsContact CD1-CB 3.47Å; Y415-S455 VanDerWaalsContact CE1-CB 3.42Å
416A98.3Very high96.6Very high11 Ų1132.9 Ų32.99%0.09118%0.175CC..G310 helixtrans-56.9-27.3177.500000112.7N418 L419 T454 L472A416-N418 PolarHBondContact O-N 2.87Å; A416-L419 PolarHBondContact O-N 3.39Å; A416-T454 PolarHBondContact N-O 3.33Å; A416-L472 HydrophobicContact CB-CB 4.23Å; A416-L472 HydrophobicContact CB-CD1 4.23Å
417S98.3Very high96.7Very high3 Ų330.4 Ų30.42%0.02116%0.16CC..G310 helixtrans-62.7-19.9174.457.70000114.2R324 V348 Y415 L419 A420R324-S417 VanDerWaalsContact CZ-OG 3.22Å; R324-S417 PolarHBondContact NH1-OG 3.39Å; R324-S417 PolarHBondContact NH2-OG 3.26Å; V348-S417 VanDerWaalsContact CG1-O 3.27Å; V348-S417 WeakPolarHBondContact CG1-O 3.29Å; Y415-S417 WeakPolarHBondContact CB-OG 3.46Å; Y415-S417 PolarHBondContact O-N 3.18Å; S417-L419 PolarHBondContact O-N 3.32Å; S417-A420 VanDerWaalsContact O-CB 3.29Å; S417-A420 WeakPolarHBondContact O-CB 3.31Å; S417-A420 PolarHBondContact O-N 3.49Å
418N98.7Very high96.8Very high1 Ų130.8 Ų30.81%0.00517%0.165CC..G310 helixtrans-54.3-26.7172.7-64.7139.6000112W400 F401 A413 F414 Y415 A416 Y439W400-N418 WeakPolarHBondContact O-CA 3.27Å; W400-N418 WeakPolarHBondContact O-CB 3.36Å; W400-N418 VanDerWaalsContact O-CG 3.31Å; W400-N418 PolarHBondContact O-ND2 3.02Å; F401-N418 WeakPolarHBondContact CD1-ND2 3.48Å; A413-N418 PolarHBondContact O-OD1 3.42Å; F414-N418 WeakPolarHBondContact CA-OD1 3.45Å; Y415-N418 PolarHBondContact N-OD1 3.1Å; Y415-N418 VanDerWaalsContact O-CB 3.24Å; Y415-N418 WeakPolarHBondContact O-CB 3.42Å; Y415-N418 PolarHBondContact O-N 3.49Å; Y415-N418 PolarHBondContact O-OD1 2.65Å; A416-N418 PolarHBondContact O-N 2.87Å; N418-Y439 HydrophobicContact CB-CE1 4.1Å; N418-Y439 PolarHBondContact OD1-OH 3.44Å
419L98.5Very high96.9Very high9 Ų931 Ų315%0.04716%0.163CC..G310 helixtrans-103.63.2-177.7-51.1-161.5000114.1A399 A416 S417 V422 A436 Y439 L440 L476A399-L419 HydrophobicContact CB-CD2 4.43Å; A416-L419 PolarHBondContact O-N 3.39Å; S417-L419 PolarHBondContact O-N 3.32Å; L419-V422 VanDerWaalsContact O-CB 3.32Å; L419-V422 WeakPolarHBondContact O-CB 3.18Å; L419-V422 PolarHBondContact O-N 2.85Å; L419-A436 HydrophobicContact CD2-CB 4Å; L419-Y439 HydrophobicContact CD2-CD1 3.87Å; L419-Y439 HydrophobicContact CD2-CE1 4.22Å; L419-L440 HydrophobicContact CD1-CB 3.79Å; L419-L440 HydrophobicContact CD1-CD1 4.05Å; L419-L440 HydrophobicContact CD1-CD2 3.87Å; L419-L440 HydrophobicContact CD1-CG 4.1Å; L419-L476 HydrophobicContact CB-CD1 4.28Å; L419-L476 HydrophobicContact CD1-CD1 3.68Å; L419-L476 HydrophobicContact CG-CD1 4.5Å
420A98.6Very high96.8Very high4 Ų433.2 Ų33.23%0.03318%0.176CC..Hα-helixtrans-52.9-33.4175.200000114D349 A352 S417 V422 W423 A424 M475D349-A420 HydrophobicContact CB-CB 3.95Å; A352-A420 HydrophobicContact CB-CB 4.06Å; S417-A420 VanDerWaalsContact O-CB 3.29Å; S417-A420 WeakPolarHBondContact O-CB 3.31Å; S417-A420 PolarHBondContact O-N 3.49Å; A420-V422 VanDerWaalsContact C-N 3.25Å; A420-V422 PolarHBondContact O-N 2.93Å; A420-W423 WeakPolarHBondContact O-CB 2.92Å; A420-W423 PolarHBondContact O-N 3.39Å; A420-A424 WeakPolarHBondContact O-CB 3.47Å; A420-A424 PolarHBondContact O-N 2.91Å; A420-M475 HydrophobicContact CB-CE 4.18Å
421P98.8Very high96.8Very high0 Ų032.7 Ų32.70%018%0.178CC..Hα-helixtrans-64.5-27.4175.3-2639.1000113.7V348 A352 M388 W400 Q425 C426 F427V348-P421 HydrophobicContact CG1-CG 3.56Å; A352-P421 HydrophobicContact CB-CB 4.49Å; A352-P421 HydrophobicContact CB-CG 4.09Å; M388-P421 HydrophobicContact CE-CB 4.27Å; M388-P421 HydrophobicContact CE-CG 3.78Å; W400-P421 HydrophobicContact CB-CG 4.07Å; W400-P421 HydrophobicContact CD2-CB 3.72Å; W400-P421 HydrophobicContact CD2-CG 3.52Å; W400-P421 HydrophobicContact CE3-CB 3.82Å; W400-P421 HydrophobicContact CE3-CG 3.79Å; W400-P421 HydrophobicContact CG-CB 4.32Å; W400-P421 HydrophobicContact CG-CG 3.65Å; W400-P421 HydrophobicContact CH2-CB 4.13Å; W400-P421 HydrophobicContact CZ2-CB 4.02Å; W400-P421 HydrophobicContact CZ3-CB 4.02Å; W400-P421 HydrophobicContact CZ3-CG 4.47Å; P421-Q425 WeakPolarHBondContact O-CA 3.48Å; P421-Q425 PolarHBondContact O-N 3.12Å; P421-C426 PolarHBondContact O-N 3.35Å; P421-F427 WeakPolarHBondContact O-CD1 3.2Å
422V98.6Very high97.1Very high7 Ų731.5 Ų31.54%0.04217%0.173CC..Hα-helixtrans-65.7-49174.1-175.60000109.9W400 L419 A420 Q425 A436 L483W400-V422 HydrophobicContact CZ3-CG2 3.94Å; L419-V422 VanDerWaalsContact O-CB 3.32Å; L419-V422 WeakPolarHBondContact O-CB 3.18Å; L419-V422 PolarHBondContact O-N 2.85Å; A420-V422 VanDerWaalsContact C-N 3.25Å; A420-V422 PolarHBondContact O-N 2.93Å; V422-Q425 PolarHBondContact O-N 3.49Å; V422-Q425 VanDerWaalsContact O-N 3.13Å; V422-A436 HydrophobicContact CG2-CB 3.72Å; V422-L483 HydrophobicContact CG1-CD2 3.87Å; V422-L483 HydrophobicContact CG1-CG 4.24Å
423W98.5Very high97.2Very high3 Ų327.3 Ų27.31%0.01116%0.155CC..Hα-helixtrans-59.9-45.6174.7170.576.7000113.1F225 L228 L353 A420 Q425 M475 E478F225-W423 HydrophobicContact CD1-CH2 4.41Å; F225-W423 AromaticContact CE1-CH2 3.48Å; F225-W423 HydrophobicContact CE1-CH2 3.48Å; F225-W423 VanDerWaalsContact CE1-CH2 3.48Å; F225-W423 AromaticContact CE1-CZ2 3.82Å; F225-W423 HydrophobicContact CE1-CZ2 3.82Å; F225-W423 AromaticContact CZ-CH2 3.85Å; F225-W423 HydrophobicContact CZ-CH2 3.85Å; F225-W423 HydrophobicContact CZ-CZ2 4.43Å; L228-W423 HydrophobicContact CD2-CH2 3.44Å; L228-W423 VanDerWaalsContact CD2-CH2 3.44Å; L228-W423 HydrophobicContact CD2-CZ2 3.61Å; L353-W423 HydrophobicContact CD1-CH2 3.89Å; L353-W423 HydrophobicContact CD1-CZ3 3.99Å; A420-W423 WeakPolarHBondContact O-CB 2.92Å; A420-W423 PolarHBondContact O-N 3.39Å; W423-Q425 PolarHBondContact O-N 2.88Å; W423-M475 HydrophobicContact CB-CB 4.27Å; W423-M475 WeakPolarHBondContact CB-O 3.24Å; W423-M475 HydrophobicContact CD2-CB 4.25Å; W423-M475 HydrophobicContact CD2-CE 3.81Å; W423-M475 HydrophobicContact CD2-CG 3.94Å; W423-M475 HydrophobicContact CE3-CE 3.47Å; W423-M475 VanDerWaalsContact CE3-CE 3.47Å; W423-M475 HydrophobicContact CG-CB 3.88Å; W423-M475 HydrophobicContact CG-CE 4.41Å; W423-M475 HydrophobicContact CG-CG 4.09Å; W423-M475 HydrophobicContact CH2-CE 4.3Å; W423-M475 HydrophobicContact CZ2-CG 4.31Å; W423-M475 HydrophobicContact CZ3-CE 3.74Å; W423-E478 VanDerWaalsContact CD1-OE2 3.31Å; W423-E478 PolarHBondContact NE1-OE2 3.09Å
424A98.3Very high97.3Very high4 Ų427.5 Ų27.53%0.03315%0.149CC..Hα-helixtrans-70.9-11.1178.100000113.2A352 R356 A420 C426A352-A424 HydrophobicContact CB-CB 3.87Å; A352-A424 VanDerWaalsContact O-CB 3.32Å; A352-A424 WeakPolarHBondContact O-CB 3.42Å; R356-A424 HydrophobicContact CB-CB 4.16Å; A420-A424 WeakPolarHBondContact O-CB 3.47Å; A420-A424 PolarHBondContact O-N 2.91Å; A424-C426 HydrophobicContact CB-CB 4.01Å; A424-C426 PolarHBondContact O-N 3.48Å; A424-C426 PolarHBondContact O-SG 3.25Å
425Q97.1Very high97.3Very high98 Ų9830.8 Ų30.846%0.45816%0.163SC..THydrogen-bonded Turntrans50.943.3-169.6-63.3179.981.400111.9K359 P421 V422 W423 K482K359-Q425 PolarHBondContact NZ-O 3.37Å; P421-Q425 WeakPolarHBondContact O-CA 3.48Å; P421-Q425 PolarHBondContact O-N 3.12Å; V422-Q425 PolarHBondContact O-N 3.49Å; V422-Q425 VanDerWaalsContact O-N 3.13Å; W423-Q425 PolarHBondContact O-N 2.88Å; Q425-K482 HydrophobicContact CG-CD 4.45Å
426C96.3Very high97.3Very high1 Ų130.6 Ų30.61%0.00716%0.163CC..  trans-112.669-172-83.50000111.9C355 P421 A424C355-C426 VanDerWaalsContact C-SG 3.54Å; C355-C426 HydrophobicContact CB-CB 3.73Å; C355-C426 WeakPolarHBondContact CB-SG 3.4Å; C355-C426 WeakPolarHBondContact SG-CB 3.24Å; C355-C426 CovalentContact SG-SG 2.03Å; C355-C426 PolarHBondContact SG-SG 2.81Å; P421-C426 PolarHBondContact O-N 3.35Å; A424-C426 HydrophobicContact CB-CB 4.01Å; A424-C426 PolarHBondContact O-N 3.48Å; A424-C426 PolarHBondContact O-SG 3.25Å
427F96.3Very high97.3Very high39 Ų3930.1 Ų30.117%0.17116%0.159CC..  trans-155.1148.3178.952.3-93.1000109.6W400 P421 Q429 M432W400-F427 HydrophobicContact CH2-CB 3.97Å; W400-F427 HydrophobicContact CH2-CD1 4.21Å; W400-F427 HydrophobicContact CH2-CG 4.23Å; W400-F427 HydrophobicContact CZ2-CB 3.58Å; W400-F427 HydrophobicContact CZ2-CG 4.33Å; P421-F427 WeakPolarHBondContact O-CD1 3.2Å; F427-Q429 VanDerWaalsContact CD2-O 3.27Å; F427-Q429 WeakPolarHBondContact CD2-O 3.36Å; F427-M432 HydrophobicContact CB-CB 4.35Å; F427-M432 HydrophobicContact CB-CE 4.43Å; F427-M432 HydrophobicContact CB-SD 4.05Å; F427-M432 HydrophobicContact CD2-CB 4.27Å; F427-M432 HydrophobicContact CG-CB 4.48Å
428S95.3Very high97.3Very high62 Ų6233.9 Ų33.943%0.43418%0.176SC..SBendtrans-83.6-28.6-169.663.70000113.9M385 E389M385-S428 PolarHBondContact SD-N 2.98Å; M385-S428 VanDerWaalsContact SD-N 3.44Å; E389-S428 WeakPolarHBondContact OE1-CB 3.39Å; E389-S428 PolarHBondContact OE1-N 3.38Å; E389-S428 PolarHBondContact OE1-OG 3.47Å; E389-S428 PolarHBondContact OE2-OG 3.15Å
429Q95.5Very high97.3Very high108 Ų10835.2 Ų35.251%0.50518%0.181SC..SBendtrans-118.1127-176.3-53.9-17923.700111.2F427 D431 M432F427-Q429 VanDerWaalsContact CD2-O 3.27Å; F427-Q429 WeakPolarHBondContact CD2-O 3.36Å; Q429-D431 WeakPolarHBondContact CB-OD1 3.25Å; Q429-D431 PolarHBondContact O-N 3.41Å; Q429-D431 VanDerWaalsContact O-N 3.12Å; Q429-M432 HydrophobicContact CB-CG 4.1Å; Q429-M432 HydrophobicContact CB-SD 4.22Å; Q429-M432 WeakPolarHBondContact O-CB 3.39Å; Q429-M432 WeakPolarHBondContact O-CG 3.48Å; Q429-M432 PolarHBondContact O-N 2.9Å
430P91.9Very high97.3Very high99 Ų9934.8 Ų34.864%0.64318%0.179SC*.Hα-helixtrans-53.7-32-179.4-3036.4000115.2M432 G433P430-M432 PolarHBondContact O-N 3.25Å; P430-G433 PolarHBondContact O-N 3.23Å
431D95.8Very high97.3Very high60 Ų6038.7 Ų38.732%0.32120%0.195SC..Hα-helixtrans-67.8-19.7179.373.4-48.8000113.2Q429 G433 E434 K435Q429-D431 WeakPolarHBondContact CB-OD1 3.25Å; Q429-D431 PolarHBondContact O-N 3.41Å; Q429-D431 VanDerWaalsContact O-N 3.12Å; D431-G433 VanDerWaalsContact C-N 3.32Å; D431-G433 PolarHBondContact O-N 3.42Å; D431-E434 PolarHBondContact O-N 3.37Å; D431-K435 WeakPolarHBondContact O-CG 3.48Å; D431-K435 PolarHBondContact O-N 2.81Å; D431-K435 WeakPolarHBondContact OD2-CE 3.4Å; D431-K435 IonicContact OD2-NZ 3.05Å; D431-K435 PolarHBondContact OD2-NZ 3.26Å
432M98.1Very high97.3Very high7 Ų743 Ų433%0.03423%0.231CC..Hα-helixtrans-63.8-38.3174.9-64.5176.276.900111.7E389 W393 W400 F427 Q429 P430 E434 K435 A436E389-M432 HydrophobicContact CG-CE 3.93Å; W393-M432 HydrophobicContact CB-CE 4.36Å; W393-M432 HydrophobicContact CD2-CE 3.33Å; W393-M432 VanDerWaalsContact CE2-CE 3.44Å; W393-M432 HydrophobicContact CE3-CE 3.71Å; W393-M432 HydrophobicContact CG-CE 3.64Å; W393-M432 HydrophobicContact CH2-CB 3.92Å; W393-M432 HydrophobicContact CH2-CE 4.2Å; W393-M432 HydrophobicContact CH2-CG 4.22Å; W393-M432 HydrophobicContact CZ2-CB 4.19Å; W393-M432 HydrophobicContact CZ2-CE 3.9Å; W393-M432 HydrophobicContact CZ2-CG 3.97Å; W393-M432 HydrophobicContact CZ3-CB 4.41Å; W393-M432 HydrophobicContact CZ3-CE 4.11Å; W400-M432 HydrophobicContact CH2-CB 4.02Å; W400-M432 HydrophobicContact CH2-CE 4.36Å; W400-M432 HydrophobicContact CZ2-CB 4.26Å; W400-M432 HydrophobicContact CZ2-CE 3.51Å; F427-M432 HydrophobicContact CB-CB 4.35Å; F427-M432 HydrophobicContact CB-CE 4.43Å; F427-M432 HydrophobicContact CB-SD 4.05Å; F427-M432 HydrophobicContact CD2-CB 4.27Å; F427-M432 HydrophobicContact CG-CB 4.48Å; Q429-M432 HydrophobicContact CB-CG 4.1Å; Q429-M432 HydrophobicContact CB-SD 4.22Å; Q429-M432 WeakPolarHBondContact O-CB 3.39Å; Q429-M432 WeakPolarHBondContact O-CG 3.48Å; Q429-M432 PolarHBondContact O-N 2.9Å; P430-M432 PolarHBondContact O-N 3.25Å; M432-E434 VanDerWaalsContact C-N 3.33Å; M432-K435 PolarHBondContact O-N 3.3Å; M432-A436 WeakPolarHBondContact O-CB 3.38Å; M432-A436 PolarHBondContact O-N 2.71Å
433G97.6Very high97.3Very high0 Ų044 Ų440%024%0.238CC..Hα-helixtrans-63.3-39.917400000112.1P430 D431 A436 L437P430-G433 PolarHBondContact O-N 3.23Å; D431-G433 VanDerWaalsContact C-N 3.32Å; D431-G433 PolarHBondContact O-N 3.42Å; G433-A436 WeakPolarHBondContact O-CB 3.32Å; G433-A436 PolarHBondContact O-N 3.43Å; G433-L437 PolarHBondContact O-N 2.88Å
434E97Very high97.2Very high41 Ų4144.8 Ų44.819%0.19225%0.247CC..Hα-helixtrans-70.1-36.7176.7-57.7-58.5160.100112.2D431 M432 A436 L437 Q438 S485D431-E434 PolarHBondContact O-N 3.37Å; M432-E434 VanDerWaalsContact C-N 3.33Å; E434-A436 VanDerWaalsContact C-N 3.35Å; E434-L437 WeakPolarHBondContact O-CB 3.03Å; E434-L437 PolarHBondContact O-N 2.87Å; E434-Q438 WeakPolarHBondContact O-CG 3.37Å; E434-Q438 PolarHBondContact O-N 2.98Å; E434-S485 VanDerWaalsContact CD-OG 3.25Å; E434-S485 VanDerWaalsContact OE1-CB 3.3Å; E434-S485 WeakPolarHBondContact OE1-CB 3.12Å; E434-S485 PolarHBondContact OE1-N 2.94Å; E434-S485 PolarHBondContact OE1-OG 3.43Å; E434-S485 WeakPolarHBondContact OE2-CB 3.36Å; E434-S485 PolarHBondContact OE2-OG 2.82Å
435K98.4Very high97.2Very high85 Ų8544.6 Ų44.637%0.3725%0.245SC..Hα-helixtrans-62.5-42171.6-77.1168.7175.9158.40111.6W393 G398 D431 M432 L437 Q438 Y439W393-K435 HydrophobicContact CH2-CB 4.04Å; W393-K435 HydrophobicContact CH2-CD 4.45Å; W393-K435 HydrophobicContact CZ2-CB 4.49Å; W393-K435 HydrophobicContact CZ2-CD 4.09Å; G398-K435 CarbonylContact O-C 3.56Å; G398-K435 VanDerWaalsContact O-C 3.22Å; D431-K435 WeakPolarHBondContact O-CG 3.48Å; D431-K435 PolarHBondContact O-N 2.81Å; D431-K435 WeakPolarHBondContact OD2-CE 3.4Å; D431-K435 IonicContact OD2-NZ 3.05Å; D431-K435 PolarHBondContact OD2-NZ 3.26Å; M432-K435 PolarHBondContact O-N 3.3Å; K435-L437 VanDerWaalsContact C-N 3.31Å; K435-L437 PolarHBondContact O-N 3.47Å; K435-Q438 PolarHBondContact O-N 3.37Å; K435-Q438 VanDerWaalsContact O-N 3.09Å; K435-Y439 PolarHBondContact O-N 2.97Å
436A98.5Very high97.2Very high0 Ų041 Ų410%023%0.229CC..Hα-helixtrans-63.6-36.5176.200000112.5G398 W400 L419 V422 M432 G433 E434 Y439 L440G398-A436 WeakPolarHBondContact O-CA 3.33Å; G398-A436 PolarHBondContact O-N 3.3Å; W400-A436 HydrophobicContact CZ3-CB 3.89Å; L419-A436 HydrophobicContact CD2-CB 4Å; V422-A436 HydrophobicContact CG2-CB 3.72Å; M432-A436 WeakPolarHBondContact O-CB 3.38Å; M432-A436 PolarHBondContact O-N 2.71Å; G433-A436 WeakPolarHBondContact O-CB 3.32Å; G433-A436 PolarHBondContact O-N 3.43Å; E434-A436 VanDerWaalsContact C-N 3.35Å; A436-Y439 WeakPolarHBondContact O-CB 3.3Å; A436-Y439 PolarHBondContact O-N 3.37Å; A436-L440 PolarHBondContact O-N 3.38Å
437L98.4Very high97.3Very high1 Ų147.2 Ų47.21%0.00526%0.262CS..Hα-helixtrans-61-44.6169.6167.564000111.7G433 E434 K435 L440 K441 L480 L483 E487 L491G433-L437 PolarHBondContact O-N 2.88Å; E434-L437 WeakPolarHBondContact O-CB 3.03Å; E434-L437 PolarHBondContact O-N 2.87Å; K435-L437 VanDerWaalsContact C-N 3.31Å; K435-L437 PolarHBondContact O-N 3.47Å; L437-L440 WeakPolarHBondContact O-CB 3.36Å; L437-L440 PolarHBondContact O-N 3.13Å; L437-K441 HydrophobicContact CD1-CD 4.19Å; L437-K441 HydrophobicContact CD1-CG 4.44Å; L437-K441 HydrophobicContact CG-CD 4.38Å; L437-K441 WeakPolarHBondContact O-CG 3.43Å; L437-K441 PolarHBondContact O-N 3.23Å; L437-K441 VanDerWaalsContact O-N 3.11Å; L437-L480 HydrophobicContact CB-CD2 4.43Å; L437-L480 HydrophobicContact CD1-CD2 3.94Å; L437-L483 HydrophobicContact CB-CD1 4.01Å; L437-L483 HydrophobicContact CD2-CD1 4.22Å; L437-E487 HydrophobicContact CD2-CB 4.26Å; L437-E487 HydrophobicContact CD2-CG 4.11Å; L437-L491 HydrophobicContact CD1-CB 4.48Å; L437-L491 HydrophobicContact CD1-CD2 3.43Å; L437-L491 VanDerWaalsContact CD1-CD2 3.43Å
438Q98.4Very high97.3Very high82 Ų8246.8 Ų46.838%0.38326%0.261SS..Hα-helixtrans-67.1-37.5177.2-59.3-48.7-43.900112.2E434 K435 K441 A442 E487E434-Q438 WeakPolarHBondContact O-CG 3.37Å; E434-Q438 PolarHBondContact O-N 2.98Å; K435-Q438 PolarHBondContact O-N 3.37Å; K435-Q438 VanDerWaalsContact O-N 3.09Å; Q438-K441 PolarHBondContact O-N 3.46Å; Q438-A442 WeakPolarHBondContact O-CB 3.45Å; Q438-A442 PolarHBondContact O-N 3.12Å; Q438-E487 PolarHBondContact NE2-OE2 3.31Å
439Y98.6Very high97.3Very high29 Ų2947.1 Ų47.111%0.11426%0.261CS..Hα-helixtrans-56.8-48.9171.2167.5-101.4000111.7R397 A399 F401 F414 N418 L419 K435 A436 K441 A442 S443R397-Y439 WeakPolarHBondContact O-CB 3.21Å; A399-Y439 HydrophobicContact CB-CD1 3.44Å; A399-Y439 VanDerWaalsContact CB-CD1 3.44Å; A399-Y439 HydrophobicContact CB-CD2 3.92Å; A399-Y439 HydrophobicContact CB-CE1 3.73Å; A399-Y439 HydrophobicContact CB-CE2 4.21Å; A399-Y439 HydrophobicContact CB-CG 3.51Å; F401-Y439 HydrophobicContact CE1-CE2 4.17Å; F401-Y439 AromaticContact CE1-CZ 3.94Å; F401-Y439 WeakPolarHBondContact CE1-OH 3.38Å; F401-Y439 HydrophobicContact CZ-CD2 4.44Å; F401-Y439 AromaticContact CZ-CE2 3.73Å; F401-Y439 HydrophobicContact CZ-CE2 3.73Å; F401-Y439 AromaticContact CZ-CZ 3.88Å; F414-Y439 AromaticContact CD2-CE1 3.79Å; F414-Y439 HydrophobicContact CD2-CE1 3.79Å; F414-Y439 AromaticContact CD2-CZ 3.9Å; F414-Y439 HydrophobicContact CE2-CE1 4.08Å; N418-Y439 HydrophobicContact CB-CE1 4.1Å; N418-Y439 PolarHBondContact OD1-OH 3.44Å; L419-Y439 HydrophobicContact CD2-CD1 3.87Å; L419-Y439 HydrophobicContact CD2-CE1 4.22Å; K435-Y439 PolarHBondContact O-N 2.97Å; A436-Y439 WeakPolarHBondContact O-CB 3.3Å; A436-Y439 PolarHBondContact O-N 3.37Å; Y439-K441 VanDerWaalsContact C-N 3.29Å; Y439-K441 PolarHBondContact O-N 3.03Å; Y439-A442 CarbonylContact O-C 3.48Å; Y439-A442 PolarHBondContact O-N 2.82Å; Y439-A442 VanDerWaalsContact O-N 3.09Å; Y439-S443 WeakPolarHBondContact O-CB 3.44Å; Y439-S443 PolarHBondContact O-N 3.44Å
440L98.6Very high97.3Very high1 Ų142.4 Ų42.41%0.00524%0.239CC..Hα-helixtrans-57.4-42.7178.1-17858.7000112.3F414 L419 A436 L437 A442 S443 A445 L446 L476 L480 L491F414-L440 HydrophobicContact CE2-CD1 3.95Å; F414-L440 HydrophobicContact CZ-CD1 4.05Å; L419-L440 HydrophobicContact CD1-CB 3.79Å; L419-L440 HydrophobicContact CD1-CD1 4.05Å; L419-L440 HydrophobicContact CD1-CD2 3.87Å; L419-L440 HydrophobicContact CD1-CG 4.1Å; A436-L440 PolarHBondContact O-N 3.38Å; L437-L440 WeakPolarHBondContact O-CB 3.36Å; L437-L440 PolarHBondContact O-N 3.13Å; L440-A442 VanDerWaalsContact C-N 3.3Å; L440-A442 PolarHBondContact O-N 3.47Å; L440-S443 PolarHBondContact O-N 3.05Å; L440-S443 PolarHBondContact O-OG 3.3Å; L440-A445 HydrophobicContact CD1-CB 4.36Å; L440-L446 HydrophobicContact CD1-CD2 4.09Å; L440-L446 HydrophobicContact CD1-CG 4.36Å; L440-L446 HydrophobicContact CD2-CD2 4.1Å; L440-L446 HydrophobicContact CG-CD1 4.16Å; L440-L446 HydrophobicContact CG-CD2 3.91Å; L440-L446 HydrophobicContact CG-CG 4.03Å; L440-L476 HydrophobicContact CD2-CD1 3.84Å; L440-L476 HydrophobicContact CD2-CD2 4.32Å; L440-L476 HydrophobicContact CD2-CG 4.47Å; L440-L480 HydrophobicContact CD2-CD1 3.96Å; L440-L491 HydrophobicContact CD2-CD2 3.98Å
441K98.3Very high97.4Very high86 Ų8637.7 Ų37.737%0.37421%0.209SC..Hα-helixtrans-66.8-32.9178.1-71.5169.260.8-157.80112.6L437 Q438 Y439 L446 E487 L491L437-K441 HydrophobicContact CD1-CD 4.19Å; L437-K441 HydrophobicContact CD1-CG 4.44Å; L437-K441 HydrophobicContact CG-CD 4.38Å; L437-K441 WeakPolarHBondContact O-CG 3.43Å; L437-K441 PolarHBondContact O-N 3.23Å; L437-K441 VanDerWaalsContact O-N 3.11Å; Q438-K441 PolarHBondContact O-N 3.46Å; Y439-K441 VanDerWaalsContact C-N 3.29Å; Y439-K441 PolarHBondContact O-N 3.03Å; K441-L446 HydrophobicContact CB-CD1 4.42Å; K441-L446 HydrophobicContact CG-CD1 3.91Å; K441-E487 WeakPolarHBondContact CE-OE1 3.28Å; K441-E487 IonicContact NZ-OE1 2.65Å; K441-E487 PolarHBondContact NZ-OE1 3.06Å; K441-E487 IonicContact NZ-OE2 2.74Å; K441-L491 HydrophobicContact CG-CD2 4.45Å
442A98.1Very high97.6Very high90 Ų9034.9 Ų34.974%0.74419%0.194SC*.Hα-helixtrans-86.2-13.8-179.700000113.7Q438 Y439 L440 G444Q438-A442 WeakPolarHBondContact O-CB 3.45Å; Q438-A442 PolarHBondContact O-N 3.12Å; Y439-A442 CarbonylContact O-C 3.48Å; Y439-A442 PolarHBondContact O-N 2.82Å; Y439-A442 VanDerWaalsContact O-N 3.09Å; L440-A442 VanDerWaalsContact C-N 3.3Å; L440-A442 PolarHBondContact O-N 3.47Å; A442-G444 VanDerWaalsContact C-N 3.33Å; A442-G444 PolarHBondContact O-N 3.03Å
443S97.8Very high97.6Very high28 Ų2834.6 Ų34.620%0.19619%0.193CC..SBendtrans-76.1-17.9-171.771.60000114.4F414 Y439 L440 A445 L456F414-S443 WeakPolarHBondContact CD2-OG 3.36Å; F414-S443 WeakPolarHBondContact CE2-OG 3.23Å; Y439-S443 WeakPolarHBondContact O-CB 3.44Å; Y439-S443 PolarHBondContact O-N 3.44Å; L440-S443 PolarHBondContact O-N 3.05Å; L440-S443 PolarHBondContact O-OG 3.3Å; S443-A445 VanDerWaalsContact C-N 3.26Å; S443-A445 VanDerWaalsContact OG-CB 3.23Å; S443-A445 WeakPolarHBondContact OG-CB 3.49Å; S443-A445 PolarHBondContact OG-N 3.16Å; S443-A445 VanDerWaalsContact OG-N 3.16Å; S443-L456 WeakPolarHBondContact O-CD1 3.41Å
444G97.5Very high97.6Very high19 Ų1934.6 Ų34.620%0.19619%0.193CC..SBendtrans82.7-3.7-169.400000113.9A442 L446 D447A442-G444 VanDerWaalsContact C-N 3.33Å; A442-G444 PolarHBondContact O-N 3.03Å; G444-L446 PolarHBondContact O-N 2.64Å; G444-D447 WeakPolarHBondContact O-CB 3.49Å; G444-D447 PolarHBondContact O-N 2.59Å
445A97.7Very high97.7Very high0 Ų032.6 Ų32.60%018%0.183CC..THydrogen-bonded Turntrans-72.5-10.7-179.100000114.1F414 L440 S443 V452 L456F414-A445 HydrophobicContact CD1-CB 3.88Å; F414-A445 HydrophobicContact CD2-CB 4.2Å; F414-A445 HydrophobicContact CE1-CB 3.31Å; F414-A445 HydrophobicContact CE2-CB 3.68Å; F414-A445 HydrophobicContact CG-CB 4.3Å; F414-A445 HydrophobicContact CZ-CB 3.2Å; L440-A445 HydrophobicContact CD1-CB 4.36Å; S443-A445 VanDerWaalsContact C-N 3.26Å; S443-A445 VanDerWaalsContact OG-CB 3.23Å; S443-A445 WeakPolarHBondContact OG-CB 3.49Å; S443-A445 PolarHBondContact OG-N 3.16Å; S443-A445 VanDerWaalsContact OG-N 3.16Å; A445-V452 HydrophobicContact CB-CG1 3.88Å; A445-L456 HydrophobicContact CB-CD2 4.37Å
446L98Very high97.6Very high24 Ų2432 Ų3213%0.12618%0.184CC..THydrogen-bonded Turntrans-93.7-2176.5-61.2-176.2000113.7L440 K441 G444 F448 V452 L491 L495 R498L440-L446 HydrophobicContact CD1-CD2 4.09Å; L440-L446 HydrophobicContact CD1-CG 4.36Å; L440-L446 HydrophobicContact CD2-CD2 4.1Å; L440-L446 HydrophobicContact CG-CD1 4.16Å; L440-L446 HydrophobicContact CG-CD2 3.91Å; L440-L446 HydrophobicContact CG-CG 4.03Å; K441-L446 HydrophobicContact CB-CD1 4.42Å; K441-L446 HydrophobicContact CG-CD1 3.91Å; G444-L446 PolarHBondContact O-N 2.64Å; L446-F448 PolarHBondContact O-N 3.23Å; L446-V452 HydrophobicContact CD2-CG2 3.89Å; L446-L491 HydrophobicContact CD1-CD1 3.96Å; L446-L491 HydrophobicContact CD1-CD2 3.88Å; L446-L491 HydrophobicContact CD2-CD1 4.4Å; L446-L495 HydrophobicContact CD2-CD1 4.31Å; L446-L495 HydrophobicContact CD2-CD2 4.05Å; L446-R498 PolarHBondContact O-NH1 3.32Å
447D96.9Very high97.5Very high131 Ų13135.7 Ų35.770%0.70120%0.198SC*.  trans-76.4-3.9-174.5-65.8-17.2000112.9G444G444-D447 WeakPolarHBondContact O-CB 3.49Å; G444-D447 PolarHBondContact O-N 2.59Å
448F96.6Very high97.3Very high30 Ų3041 Ų4113%0.13223%0.226CC..  trans-96.6142.8-176.3-54.1-79.5000112.9L446 P453 L456 Y465 R498 V519 N520L446-F448 PolarHBondContact O-N 3.23Å; F448-P453 VanDerWaalsContact CD2-CD 3.46Å; F448-P453 HydrophobicContact CD2-CG 3.74Å; F448-P453 HydrophobicContact CE2-CG 3.61Å; F448-P453 HydrophobicContact CZ-CG 4.37Å; F448-L456 HydrophobicContact CE2-CD2 3.74Å; F448-L456 HydrophobicContact CZ-CD2 4.14Å; F448-Y465 HydrophobicContact CD1-CE2 4.28Å; F448-Y465 HydrophobicContact CE1-CD2 4.25Å; F448-Y465 AromaticContact CE1-CE2 3.46Å; F448-Y465 HydrophobicContact CE1-CE2 3.46Å; F448-Y465 VanDerWaalsContact CE1-CE2 3.46Å; F448-Y465 HydrophobicContact CZ-CD2 4.1Å; F448-Y465 AromaticContact CZ-CE2 3.72Å; F448-Y465 HydrophobicContact CZ-CE2 3.72Å; F448-R498 PolarHBondContact O-NH1 2.85Å; F448-V519 HydrophobicContact CB-CB 3.79Å; F448-V519 HydrophobicContact CB-CG2 3.91Å; F448-V519 HydrophobicContact CD1-CB 4.35Å; F448-V519 HydrophobicContact CD1-CG2 3.53Å; F448-V519 HydrophobicContact CD2-CG2 4.28Å; F448-V519 HydrophobicContact CE1-CG2 4.13Å; F448-V519 HydrophobicContact CG-CB 4.07Å; F448-V519 HydrophobicContact CG-CG2 3.62Å; F448-N520 WeakPolarHBondContact CD1-OD1 3.21Å
449P94.8Very high97.2Very high69 Ų6938.6 Ų38.645%0.44822%0.219SC..THydrogen-bonded Turntrans-74-30.1-176.927.3-35.1000114V519P449-V519 WeakPolarHBondContact CD-O 3.42Å; P449-V519 WeakPolarHBondContact CG-O 3.21Å
450N95.4Very high97Very high8 Ų839.2 Ų39.24%0.04323%0.234CC..THydrogen-bonded Turntrans-111.521.4-162.8-58.3-36.3000114.5T502 V519 N520 G521 G523N450-T502 VanDerWaalsContact CA-OG1 3.27Å; N450-T502 WeakPolarHBondContact CA-OG1 3.49Å; N450-T502 HydrophobicContact CB-CG2 3.7Å; N450-T502 WeakPolarHBondContact CB-OG1 3.4Å; N450-T502 PolarHBondContact OD1-OG1 3.2Å; N450-V519 WeakPolarHBondContact CB-O 3.46Å; N450-V519 PolarHBondContact N-O 2.8Å; N450-N520 PolarHBondContact ND2-O 2.86Å; N450-G521 PolarHBondContact ND2-O 2.83Å; N450-G523 WeakPolarHBondContact ND2-CA 3.12Å; N450-G523 PolarHBondContact ND2-N 2.97Å
451G95.8Very high96.9Very high1 Ų140.7 Ų40.71%0.0124%0.241CC..  trans130.3-172.6-178.900000111.6
452V98.3Very high96.9Very high1 Ų136.7 Ų36.71%0.00622%0.223CC..  trans-103.2123.6174.9179.90000108.3F414 A445 L446 A468 Q473 L476 L495F414-V452 HydrophobicContact CE1-CG1 4.26Å; F414-V452 HydrophobicContact CZ-CG1 4.04Å; A445-V452 HydrophobicContact CB-CG1 3.88Å; L446-V452 HydrophobicContact CD2-CG2 3.89Å; V452-A468 WeakPolarHBondContact O-CB 3.09Å; V452-Q473 PolarHBondContact O-NE2 3.15Å; V452-L476 HydrophobicContact CB-CD2 3.88Å; V452-L476 HydrophobicContact CG1-CD2 4.04Å; V452-L476 HydrophobicContact CG2-CD2 3.58Å; V452-L495 HydrophobicContact CG2-CD1 4.3Å; V452-L495 HydrophobicContact CG2-CD2 3.79Å
453P98.3Very high96.9Very high0 Ų032.6 Ų32.60%019%0.188CC..  trans-68.1156.2-178.130.3-36.4000110.7F448 S455 L456 Y465 N467 V519F448-P453 VanDerWaalsContact CD2-CD 3.46Å; F448-P453 HydrophobicContact CD2-CG 3.74Å; F448-P453 HydrophobicContact CE2-CG 3.61Å; F448-P453 HydrophobicContact CZ-CG 4.37Å; P453-S455 VanDerWaalsContact CB-O 3.27Å; P453-S455 WeakPolarHBondContact CB-O 3.33Å; P453-S455 WeakPolarHBondContact CG-O 3.32Å; P453-S455 PolarHBondContact O-N 2.99Å; P453-L456 HydrophobicContact CG-CD2 4.04Å; P453-Y465 HydrophobicContact CB-CD2 4.21Å; P453-Y465 HydrophobicContact CG-CD2 4.45Å; P453-N467 WeakPolarHBondContact CA-O 3.34Å; P453-V519 HydrophobicContact CB-CG1 3.86Å; P453-V519 HydrophobicContact CB-CG2 4.01Å; P453-V519 HydrophobicContact CG-CG2 4.4Å
454T98.4Very high96.9Very high0 Ų031.2 Ų31.20%018%0.179CC..SBendtrans-57.8-39.6179-62.70000112.2W319 Y415 A416 W463 N467 L472W319-T454 HydrophobicContact CD2-CG2 4.44Å; W319-T454 HydrophobicContact CE3-CG2 3.62Å; W319-T454 HydrophobicContact CH2-CG2 3.54Å; W319-T454 HydrophobicContact CZ2-CG2 4.35Å; W319-T454 HydrophobicContact CZ3-CG2 3.12Å; Y415-T454 VanDerWaalsContact CA-O 3.3Å; Y415-T454 WeakPolarHBondContact CA-O 3.44Å; A416-T454 PolarHBondContact N-O 3.33Å; T454-W463 VanDerWaalsContact CG2-C 3.47Å; T454-W463 HydrophobicContact CG2-CB 4.18Å; T454-W463 HydrophobicContact CG2-CE3 4.1Å; T454-W463 WeakPolarHBondContact CG2-O 3.39Å; T454-N467 PolarHBondContact N-O 3.41Å; T454-N467 PolarHBondContact OG1-O 2.66Å; T454-L472 HydrophobicContact CG2-CD1 3.75Å
455S98.1Very high96.9Very high0 Ų033.2 Ų33.20%018%0.181CC..BIsolated β-bridgetrans-143.4-178.8173.580.70000110F414 Y415 P453 R457 D464 Y465F414-S455 WeakPolarHBondContact O-CA 3.21Å; Y415-S455 VanDerWaalsContact CD1-CB 3.47Å; Y415-S455 VanDerWaalsContact CE1-CB 3.42Å; P453-S455 VanDerWaalsContact CB-O 3.27Å; P453-S455 WeakPolarHBondContact CB-O 3.33Å; P453-S455 WeakPolarHBondContact CG-O 3.32Å; P453-S455 PolarHBondContact O-N 2.99Å; S455-R457 PolarHBondContact OG-N 3.15Å; S455-R457 VanDerWaalsContact OG-N 3.12Å; S455-R457 PolarHBondContact OG-O 2.78Å; S455-D464 WeakPolarHBondContact CB-OD1 3.29Å; S455-D464 WeakPolarHBondContact OG-CA 3.47Å; S455-D464 PolarHBondContact OG-OD1 2.87Å; S455-Y465 WeakPolarHBondContact O-CB 3.29Å; S455-Y465 PolarHBondContact OG-N 3.4Å
456L97.4Very high96.8Very high73 Ų7334.7 Ų34.738%0.38219%0.191SC..SBendtrans-104.810.7170.1-65.2174.3000113.1F414 S443 A445 F448 P453F414-L456 HydrophobicContact CB-CD1 3.88Å; F414-L456 HydrophobicContact CB-CG 4.18Å; F414-L456 HydrophobicContact CD1-CD1 4.25Å; F414-L456 HydrophobicContact CD1-CG 3.91Å; F414-L456 HydrophobicContact CG-CD1 4.15Å; F414-L456 HydrophobicContact CG-CG 4.29Å; S443-L456 WeakPolarHBondContact O-CD1 3.41Å; A445-L456 HydrophobicContact CB-CD2 4.37Å; F448-L456 HydrophobicContact CE2-CD2 3.74Å; F448-L456 HydrophobicContact CZ-CD2 4.14Å; P453-L456 HydrophobicContact CG-CD2 4.04Å
457R95.5Very high96.9Very high77 Ų7733.7 Ų33.729%0.29119%0.185SC..  trans-106.7123.8-178-178.6169177.4-156-3.9110N333 D334 G335 S455 S459 D464 Y465N333-R457 PolarHBondContact O-NH1 3.3Å; D334-R457 VanDerWaalsContact C-NH2 3.31Å; D334-R457 VanDerWaalsContact CA-NH1 3.33Å; D334-R457 PolarHBondContact O-NH2 3.1Å; G335-R457 PolarHBondContact O-NH2 3.39Å; S455-R457 PolarHBondContact OG-N 3.15Å; S455-R457 VanDerWaalsContact OG-N 3.12Å; S455-R457 PolarHBondContact OG-O 2.78Å; R457-S459 PolarHBondContact O-N 2.89Å; R457-D464 WeakPolarHBondContact O-CB 3.41Å; R457-Y465 PolarHBondContact O-N 2.99Å
458D95.6Very high96.9Very high111 Ų11127.4 Ų27.459%0.59415%0.152SC*.BIsolated β-bridgetrans-80.9101168.8-164.9-19.2000109.2G460 Y465D458-G460 PolarHBondContact OD1-N 3.23Å; D458-Y465 HydrophobicContact CB-CD1 3.85Å; D458-Y465 HydrophobicContact CB-CE1 4.45Å
459S95.1Very high97Very high33 Ų3326 Ų2623%0.23115%0.146CC..  trans-106.5-4.7179.571.70000113.2R457 Q461 D464R457-S459 PolarHBondContact O-N 2.89Å; S459-Q461 PolarHBondContact O-N 3.14Å; S459-Q461 VanDerWaalsContact OG-CB 3.26Å; S459-Q461 WeakPolarHBondContact OG-CB 3.5Å; S459-Q461 WeakPolarHBondContact OG-CG 3.26Å; S459-Q461 PolarHBondContact OG-N 2.9Å; S459-Q461 VanDerWaalsContact OG-N 3.09Å; S459-D464 VanDerWaalsContact CB-OD2 3.25Å; S459-D464 WeakPolarHBondContact CB-OD2 3.24Å; S459-D464 WeakPolarHBondContact OG-CB 3.39Å; S459-D464 PolarHBondContact OG-OD2 3.33Å
460G95.4Very high97.2Very high42 Ų4222.8 Ų22.843%0.43313%0.125SC..SBendtrans72.5-2.6-165.700000114.9D458 G528 G529D458-G460 PolarHBondContact OD1-N 3.23Å; G460-G528 WeakPolarHBondContact O-CA 3.23Å; G460-G529 PolarHBondContact O-N 3.02Å
461Q97Very high97.3Very high32 Ų3222.4 Ų22.415%0.1512%0.123CC..SBendtrans-89.3155.8178.2-54.6-64.3-39.600111.9F321 F326 S459 W463F321-Q461 HydrophobicContact CB-CG 4.5Å; F321-Q461 WeakPolarHBondContact O-CB 3.14Å; F326-Q461 HydrophobicContact CE2-CG 3.85Å; F326-Q461 HydrophobicContact CZ-CG 3.78Å; S459-Q461 PolarHBondContact O-N 3.14Å; S459-Q461 VanDerWaalsContact OG-CB 3.26Å; S459-Q461 WeakPolarHBondContact OG-CB 3.5Å; S459-Q461 WeakPolarHBondContact OG-CG 3.26Å; S459-Q461 PolarHBondContact OG-N 2.9Å; S459-Q461 VanDerWaalsContact OG-N 3.09Å; Q461-W463 PolarHBondContact O-N 3.07Å
462Q96.2Very high97.4Very high2 Ų222.8 Ų22.81%0.00912%0.124CC..THydrogen-bonded Turntrans-73.4-27.7-170.566.5175.2-28.800114.6D320 D464 N467 W469 K516 G528 Y531D320-Q462 WeakPolarHBondContact O-CG 3.23Å; D320-Q462 PolarHBondContact O-NE2 3.29Å; Q462-D464 VanDerWaalsContact C-N 3.29Å; Q462-D464 PolarHBondContact O-N 2.8Å; Q462-N467 WeakPolarHBondContact CA-ND2 3.07Å; Q462-N467 WeakPolarHBondContact O-CB 3.34Å; Q462-N467 PolarHBondContact O-ND2 3.16Å; Q462-W469 HydrophobicContact CB-CZ2 3.93Å; Q462-W469 HydrophobicContact CG-CH2 4.36Å; Q462-W469 HydrophobicContact CG-CZ2 3.87Å; Q462-W469 PolarHBondContact O-NE1 3Å; Q462-K516 HydrophobicContact CB-CD 4.43Å; Q462-G528 WeakPolarHBondContact CB-O 3.41Å; Q462-Y531 PolarHBondContact NE2-OH 3.11Å; Q462-Y531 PolarHBondContact OE1-OH 2.87Å
463W98.1Very high97.5Very high3 Ų322.9 Ų22.91%0.01113%0.125CC..THydrogen-bonded Turntrans-9645.7176.8-69.994.4000111.8W174 G318 W319 F321 T322 T454 Q461 W469 P471 L472 W539W174-W463 AromaticContact CH2-CH2 3.44Å; W174-W463 HydrophobicContact CH2-CH2 3.44Å; W174-W463 VanDerWaalsContact CH2-CH2 3.44Å; W174-W463 HydrophobicContact CH2-CZ2 4.02Å; W174-W463 HydrophobicContact CH2-CZ3 4.01Å; W174-W463 AromaticContact CZ2-CH2 3.54Å; W174-W463 HydrophobicContact CZ2-CH2 3.54Å; W174-W463 AromaticContact CZ2-CZ2 3.72Å; W174-W463 HydrophobicContact CZ2-CZ2 3.72Å; G318-W463 WeakPolarHBondContact O-CZ2 3.24Å; G318-W463 PolarHBondContact O-NE1 3.08Å; G318-W463 VanDerWaalsContact O-NE1 3.16Å; W319-W463 VanDerWaalsContact CA-CD1 3.47Å; W319-W463 HydrophobicContact CB-CB 4.09Å; W319-W463 HydrophobicContact CB-CD2 4.06Å; W319-W463 HydrophobicContact CB-CE3 4.44Å; W319-W463 HydrophobicContact CB-CG 3.89Å; W319-W463 AromaticContact CD1-CE3 3.93Å; W319-W463 HydrophobicContact CD2-CB 4.33Å; W319-W463 HydrophobicContact CD2-CD2 4.12Å; W319-W463 AromaticContact CD2-CE3 3.63Å; W319-W463 HydrophobicContact CD2-CE3 3.63Å; W319-W463 HydrophobicContact CD2-CG 4.43Å; W319-W463 HydrophobicContact CD2-CZ3 4.29Å; W319-W463 AromaticContact CE2-CE3 3.83Å; W319-W463 HydrophobicContact CE3-CB 4.03Å; W319-W463 HydrophobicContact CE3-CE3 4.15Å; W319-W463 HydrophobicContact CG-CB 4.38Å; W319-W463 AromaticContact CG-CD2 3.85Å; W319-W463 HydrophobicContact CG-CD2 3.85Å; W319-W463 AromaticContact CG-CE3 3.74Å; W319-W463 HydrophobicContact CG-CE3 3.74Å; W319-W463 HydrophobicContact CG-CG 4.13Å; W319-W463 HydrophobicContact CG-CZ3 4.31Å; W319-W463 AromaticContact NE1-CE3 3.95Å; W319-W463 AromaticContact NE1-CZ3 3.84Å; F321-W463 WeakPolarHBondContact O-CB 3.32Å; F321-W463 PolarHBondContact O-N 3.05Å; T322-W463 WeakPolarHBondContact CB-O 3.11Å; T322-W463 HydrophobicContact CG2-CB 4.32Å; T322-W463 PolarHBondContact OG1-O 2.93Å; T454-W463 VanDerWaalsContact CG2-C 3.47Å; T454-W463 HydrophobicContact CG2-CB 4.18Å; T454-W463 HydrophobicContact CG2-CE3 4.1Å; T454-W463 WeakPolarHBondContact CG2-O 3.39Å; Q461-W463 PolarHBondContact O-N 3.07Å; W463-W469 HydrophobicContact CD2-CD2 4.03Å; W463-W469 AromaticContact CD2-CE2 3.68Å; W463-W469 HydrophobicContact CD2-CG 4.36Å; W463-W469 AromaticContact CD2-CZ2 3.94Å; W463-W469 HydrophobicContact CD2-CZ2 3.94Å; W463-W469 AromaticContact CD2-NE1 3.88Å; W463-W469 AromaticContact CE2-CD2 3.86Å; W463-W469 AromaticContact CE2-CE2 3.67Å; W463-W469 AromaticContact CE2-CE3 3.96Å; W463-W469 AromaticContact CE2-CH2 3.71Å; W463-W469 AromaticContact CE2-CZ2 3.59Å; W463-W469 AromaticContact CE2-CZ3 3.87Å; W463-W469 HydrophobicContact CE3-CB 4.42Å; W463-W469 AromaticContact CE3-CD1 3.86Å; W463-W469 AromaticContact CE3-CD2 3.94Å; W463-W469 HydrophobicContact CE3-CD2 3.94Å; W463-W469 AromaticContact CE3-CE2 3.96Å; W463-W469 AromaticContact CE3-CG 3.82Å; W463-W469 HydrophobicContact CE3-CG 3.82Å; W463-W469 AromaticContact CE3-NE1 3.91Å; W463-W469 HydrophobicContact CG-CZ2 4.17Å; W463-W469 HydrophobicContact CH2-CB 4.02Å; W463-W469 AromaticContact CH2-CD2 3.5Å; W463-W469 HydrophobicContact CH2-CD2 3.5Å; W463-W469 AromaticContact CH2-CE3 3.45Å; W463-W469 HydrophobicContact CH2-CE3 3.45Å; W463-W469 VanDerWaalsContact CH2-CE3 3.45Å; W463-W469 AromaticContact CH2-CG 3.79Å; W463-W469 HydrophobicContact CH2-CG 3.79Å; W463-W469 HydrophobicContact CH2-CZ3 4.04Å; W463-W469 AromaticContact CZ2-CD2 3.61Å; W463-W469 HydrophobicContact CZ2-CD2 3.61Å; W463-W469 AromaticContact CZ2-CE2 3.92Å; W463-W469 AromaticContact CZ2-CE3 3.36Å; W463-W469 HydrophobicContact CZ2-CE3 3.36Å; W463-W469 HydrophobicContact CZ2-CG 4.34Å; W463-W469 AromaticContact CZ2-CH2 3.79Å; W463-W469 HydrophobicContact CZ2-CH2 3.79Å; W463-W469 HydrophobicContact CZ2-CZ2 4.01Å; W463-W469 AromaticContact CZ2-CZ3 3.44Å; W463-W469 HydrophobicContact CZ2-CZ3 3.44Å; W463-W469 VanDerWaalsContact CZ2-CZ3 3.44Å; W463-W469 HydrophobicContact CZ3-CB 3.72Å; W463-W469 AromaticContact CZ3-CD2 3.69Å; W463-W469 HydrophobicContact CZ3-CD2 3.69Å; W463-W469 HydrophobicContact CZ3-CE3 4.13Å; W463-W469 AromaticContact CZ3-CG 3.51Å; W463-W469 HydrophobicContact CZ3-CG 3.51Å; W463-W469 AromaticContact NE1-CH2 3.7Å; W463-W469 AromaticContact NE1-CZ2 3.63Å; W463-P471 HydrophobicContact CH2-CG 4.29Å; W463-L472 HydrophobicContact CE3-CD1 4.11Å; W463-L472 HydrophobicContact CZ3-CD1 3.85Å; W463-L472 HydrophobicContact CZ3-CD2 4.49Å; W463-L472 HydrophobicContact CZ3-CG 4.09Å; W463-W539 AromaticContact CH2-CH2 3.89Å; W463-W539 HydrophobicContact CH2-CH2 3.89Å; W463-W539 HydrophobicContact CH2-CZ3 4.22Å; W463-W539 AromaticContact CZ2-CH2 3.84Å; W463-W539 HydrophobicContact CZ2-CH2 3.84Å; W463-W539 HydrophobicContact CZ2-CZ3 4.45Å
464D98.1Very high97.5Very high0 Ų023.1 Ų23.10%013%0.126CC..SBendtrans-147.2174.4178.2-93.5-35.7000110.5T322 S323 S455 R457 S459 Q462 N467T322-D464 PolarHBondContact OG1-OD1 3.21Å; S323-D464 WeakPolarHBondContact CB-OD2 3.41Å; S323-D464 PolarHBondContact N-OD2 3.16Å; S323-D464 VanDerWaalsContact OG-CG 3.25Å; S323-D464 PolarHBondContact OG-OD1 3.04Å; S323-D464 PolarHBondContact OG-OD2 3.08Å; S455-D464 WeakPolarHBondContact CB-OD1 3.29Å; S455-D464 WeakPolarHBondContact OG-CA 3.47Å; S455-D464 PolarHBondContact OG-OD1 2.87Å; R457-D464 WeakPolarHBondContact O-CB 3.41Å; S459-D464 VanDerWaalsContact CB-OD2 3.25Å; S459-D464 WeakPolarHBondContact CB-OD2 3.24Å; S459-D464 WeakPolarHBondContact OG-CB 3.39Å; S459-D464 PolarHBondContact OG-OD2 3.33Å; Q462-D464 VanDerWaalsContact C-N 3.29Å; Q462-D464 PolarHBondContact O-N 2.8Å; D464-N467 WeakPolarHBondContact O-CB 3.36Å; D464-N467 PolarHBondContact O-N 2.98Å
465Y97.6Very high97.5Very high60 Ų6024.2 Ų24.224%0.23513%0.131CC..BIsolated β-bridgetrans-54.2136.7170.2175.4-90.6000110.4F448 P453 S455 R457 D458 V519 N520F448-Y465 HydrophobicContact CD1-CE2 4.28Å; F448-Y465 HydrophobicContact CE1-CD2 4.25Å; F448-Y465 AromaticContact CE1-CE2 3.46Å; F448-Y465 HydrophobicContact CE1-CE2 3.46Å; F448-Y465 VanDerWaalsContact CE1-CE2 3.46Å; F448-Y465 HydrophobicContact CZ-CD2 4.1Å; F448-Y465 AromaticContact CZ-CE2 3.72Å; F448-Y465 HydrophobicContact CZ-CE2 3.72Å; P453-Y465 HydrophobicContact CB-CD2 4.21Å; P453-Y465 HydrophobicContact CG-CD2 4.45Å; S455-Y465 WeakPolarHBondContact O-CB 3.29Å; S455-Y465 PolarHBondContact OG-N 3.4Å; R457-Y465 PolarHBondContact O-N 2.99Å; D458-Y465 HydrophobicContact CB-CD1 3.85Å; D458-Y465 HydrophobicContact CB-CE1 4.45Å; Y465-V519 HydrophobicContact CD2-CG2 4.27Å; Y465-V519 HydrophobicContact CE2-CG2 4.03Å; Y465-N520 PolarHBondContact OH-ND2 3.4Å
466P97.3Very high97.5Very high31 Ų3124.8 Ų24.820%0.20113%0.134CC..THydrogen-bonded Turncis-95.314.41039-37.6000115.2V519 N520P466-V519 HydrophobicContact CB-CG2 4.46Å; P466-V519 WeakPolarHBondContact O-CG2 3.4Å; P466-V519 PolarHBondContact O-N 3.29Å; P466-N520 WeakPolarHBondContact CB-ND2 3.38Å
467N98.2Very high97.6Very high3 Ų321.4 Ų21.42%0.01612%0.116CC..EExtended strand (participates in β ladder)trans-80.9140.3-172.7-62-44.2000112.5P453 T454 Q462 D464 Y517 G526 G527P453-N467 WeakPolarHBondContact CA-O 3.34Å; T454-N467 PolarHBondContact N-O 3.41Å; T454-N467 PolarHBondContact OG1-O 2.66Å; Q462-N467 WeakPolarHBondContact CA-ND2 3.07Å; Q462-N467 WeakPolarHBondContact O-CB 3.34Å; Q462-N467 PolarHBondContact O-ND2 3.16Å; D464-N467 WeakPolarHBondContact O-CB 3.36Å; D464-N467 PolarHBondContact O-N 2.98Å; N467-Y517 CarbonylContact C-O 3.46Å; N467-Y517 WeakPolarHBondContact CA-O 3.46Å; N467-G526 WeakPolarHBondContact OD1-CA 3.24Å; N467-G527 PolarHBondContact ND2-O 3.08Å; N467-G527 PolarHBondContact OD1-N 3.2Å
468A97.9Very high97.7Very high0 Ų018.8 Ų18.80%011%0.108CC..EExtended strand (participates in β ladder)trans-114.7137.1163.200000110.2V452 W499 Y517 V519V452-A468 WeakPolarHBondContact O-CB 3.09Å; A468-W499 HydrophobicContact CB-CH2 4.26Å; A468-W499 HydrophobicContact CB-CZ3 3.84Å; A468-Y517 PolarHBondContact N-O 3.37Å; A468-Y517 PolarHBondContact O-N 3.19Å; A468-V519 HydrophobicContact CB-CG1 3.38Å
469W98.4Very high97.9Very high1 Ų113.6 Ų13.60%0.0048%0.08CC..  trans-113.4131.3-176.2-69.372.1000110.7Q462 W463 P471 L472 Q473 E515 K516 W539Q462-W469 HydrophobicContact CB-CZ2 3.93Å; Q462-W469 HydrophobicContact CG-CH2 4.36Å; Q462-W469 HydrophobicContact CG-CZ2 3.87Å; Q462-W469 PolarHBondContact O-NE1 3Å; W463-W469 HydrophobicContact CD2-CD2 4.03Å; W463-W469 AromaticContact CD2-CE2 3.68Å; W463-W469 HydrophobicContact CD2-CG 4.36Å; W463-W469 AromaticContact CD2-CZ2 3.94Å; W463-W469 HydrophobicContact CD2-CZ2 3.94Å; W463-W469 AromaticContact CD2-NE1 3.88Å; W463-W469 AromaticContact CE2-CD2 3.86Å; W463-W469 AromaticContact CE2-CE2 3.67Å; W463-W469 AromaticContact CE2-CE3 3.96Å; W463-W469 AromaticContact CE2-CH2 3.71Å; W463-W469 AromaticContact CE2-CZ2 3.59Å; W463-W469 AromaticContact CE2-CZ3 3.87Å; W463-W469 HydrophobicContact CE3-CB 4.42Å; W463-W469 AromaticContact CE3-CD1 3.86Å; W463-W469 AromaticContact CE3-CD2 3.94Å; W463-W469 HydrophobicContact CE3-CD2 3.94Å; W463-W469 AromaticContact CE3-CE2 3.96Å; W463-W469 AromaticContact CE3-CG 3.82Å; W463-W469 HydrophobicContact CE3-CG 3.82Å; W463-W469 AromaticContact CE3-NE1 3.91Å; W463-W469 HydrophobicContact CG-CZ2 4.17Å; W463-W469 HydrophobicContact CH2-CB 4.02Å; W463-W469 AromaticContact CH2-CD2 3.5Å; W463-W469 HydrophobicContact CH2-CD2 3.5Å; W463-W469 AromaticContact CH2-CE3 3.45Å; W463-W469 HydrophobicContact CH2-CE3 3.45Å; W463-W469 VanDerWaalsContact CH2-CE3 3.45Å; W463-W469 AromaticContact CH2-CG 3.79Å; W463-W469 HydrophobicContact CH2-CG 3.79Å; W463-W469 HydrophobicContact CH2-CZ3 4.04Å; W463-W469 AromaticContact CZ2-CD2 3.61Å; W463-W469 HydrophobicContact CZ2-CD2 3.61Å; W463-W469 AromaticContact CZ2-CE2 3.92Å; W463-W469 AromaticContact CZ2-CE3 3.36Å; W463-W469 HydrophobicContact CZ2-CE3 3.36Å; W463-W469 HydrophobicContact CZ2-CG 4.34Å; W463-W469 AromaticContact CZ2-CH2 3.79Å; W463-W469 HydrophobicContact CZ2-CH2 3.79Å; W463-W469 HydrophobicContact CZ2-CZ2 4.01Å; W463-W469 AromaticContact CZ2-CZ3 3.44Å; W463-W469 HydrophobicContact CZ2-CZ3 3.44Å; W463-W469 VanDerWaalsContact CZ2-CZ3 3.44Å; W463-W469 HydrophobicContact CZ3-CB 3.72Å; W463-W469 AromaticContact CZ3-CD2 3.69Å; W463-W469 HydrophobicContact CZ3-CD2 3.69Å; W463-W469 HydrophobicContact CZ3-CE3 4.13Å; W463-W469 AromaticContact CZ3-CG 3.51Å; W463-W469 HydrophobicContact CZ3-CG 3.51Å; W463-W469 AromaticContact NE1-CH2 3.7Å; W463-W469 AromaticContact NE1-CZ2 3.63Å; W469-P471 VanDerWaalsContact C-CD 3.41Å; W469-P471 HydrophobicContact CB-CG 4.16Å; W469-L472 HydrophobicContact CB-CD1 4.28Å; W469-L472 HydrophobicContact CB-CG 4.21Å; W469-L472 PolarHBondContact O-N 3.44Å; W469-Q473 WeakPolarHBondContact O-CG 3.34Å; W469-Q473 PolarHBondContact O-N 3.47Å; W469-Q473 VanDerWaalsContact O-N 3.11Å; W469-E515 HydrophobicContact CE3-CG 4.22Å; W469-E515 HydrophobicContact CH2-CG 3.95Å; W469-E515 HydrophobicContact CZ3-CG 3.44Å; W469-E515 VanDerWaalsContact CZ3-CG 3.44Å; W469-K516 HydrophobicContact CD2-CB 3.82Å; W469-K516 HydrophobicContact CD2-CD 4.43Å; W469-K516 HydrophobicContact CE3-CB 4.08Å; W469-K516 HydrophobicContact CG-CB 4.28Å; W469-K516 HydrophobicContact CH2-CB 4.41Å; W469-K516 HydrophobicContact CH2-CD 3.53Å; W469-K516 HydrophobicContact CZ2-CB 4.13Å; W469-K516 HydrophobicContact CZ2-CD 3.17Å; W469-K516 HydrophobicContact CZ2-CG 4.27Å; W469-K516 HydrophobicContact CZ3-CB 4.38Å; W469-K516 HydrophobicContact CZ3-CD 4.28Å; W469-W539 HydrophobicContact CD2-CZ2 4.45Å; W469-W539 AromaticContact CE3-CH2 3.3Å; W469-W539 HydrophobicContact CE3-CH2 3.3Å; W469-W539 AromaticContact CE3-CZ2 3.12Å; W469-W539 HydrophobicContact CE3-CZ2 3.12Å; W469-W539 HydrophobicContact CE3-CZ3 4.45Å; W469-W539 AromaticContact CZ3-CH2 3.37Å; W469-W539 HydrophobicContact CZ3-CH2 3.37Å; W469-W539 AromaticContact CZ3-CZ2 3.21Å; W469-W539 HydrophobicContact CZ3-CZ2 3.21Å
470P98.3Very high98Very high0 Ų012.2 Ų12.20%07%0.07CC..Hα-helixtrans-45-47.1178.5-19.822.7000115.4L472 Q473 H474 W499 E515 W539 T540 V543P470-L472 VanDerWaalsContact C-N 3.31Å; P470-L472 PolarHBondContact O-N 3.49Å; P470-Q473 PolarHBondContact O-N 3.38Å; P470-H474 WeakPolarHBondContact O-CB 3.31Å; P470-H474 PolarHBondContact O-N 3.32Å; P470-W499 HydrophobicContact CB-CZ2 3.98Å; P470-W499 HydrophobicContact CG-CZ2 3.85Å; P470-E515 VanDerWaalsContact CD-O 3.22Å; P470-E515 WeakPolarHBondContact CD-O 3.14Å; P470-W539 HydrophobicContact CB-CG 4.41Å; P470-W539 HydrophobicContact CG-CG 4.39Å; P470-T540 HydrophobicContact CG-CG2 3.97Å; P470-T540 WeakPolarHBondContact CG-OG1 3.46Å; P470-V543 HydrophobicContact CB-CB 4.07Å; P470-V543 HydrophobicContact CB-CG1 4.34Å; P470-V543 HydrophobicContact CB-CG2 3.9Å
471P98.5Very high98.2Very high0 Ų011.5 Ų11.50%06%0.059CC..Hα-helixtrans-59.2-41.1179.724-38.4000113W178 W463 W469 H474 M475 W539W178-P471 HydrophobicContact CD2-CB 4.15Å; W178-P471 HydrophobicContact CE3-CB 4.06Å; W178-P471 HydrophobicContact CH2-CB 3.15Å; W178-P471 HydrophobicContact CH2-CG 4.4Å; W178-P471 HydrophobicContact CZ2-CB 3.21Å; W178-P471 HydrophobicContact CZ3-CB 3.58Å; W463-P471 HydrophobicContact CH2-CG 4.29Å; W469-P471 VanDerWaalsContact C-CD 3.41Å; W469-P471 HydrophobicContact CB-CG 4.16Å; P471-H474 PolarHBondContact O-N 3.32Å; P471-M475 WeakPolarHBondContact O-CB 2.95Å; P471-M475 VanDerWaalsContact O-CG 3.25Å; P471-M475 WeakPolarHBondContact O-CG 3.27Å; P471-M475 PolarHBondContact O-N 3.35Å; P471-W539 HydrophobicContact CB-CE3 4.24Å; P471-W539 HydrophobicContact CG-CD2 4.16Å; P471-W539 HydrophobicContact CG-CE3 3.61Å; P471-W539 HydrophobicContact CG-CH2 4.34Å; P471-W539 HydrophobicContact CG-CZ3 3.7Å
472L98.8Very high98.1Very high9 Ų913.8 Ų13.85%0.0477%0.068CC..Hα-helixtrans-69.9-38.1-180-54.7-175.7000111.6W319 A416 T454 W463 W469 P470 L476W319-L472 HydrophobicContact CH2-CD1 3.8Å; W319-L472 HydrophobicContact CH2-CD2 4.37Å; W319-L472 HydrophobicContact CZ2-CD1 3.58Å; W319-L472 HydrophobicContact CZ2-CD2 3.47Å; W319-L472 VanDerWaalsContact CZ2-CD2 3.47Å; W319-L472 HydrophobicContact CZ2-CG 4.17Å; A416-L472 HydrophobicContact CB-CB 4.23Å; A416-L472 HydrophobicContact CB-CD1 4.23Å; T454-L472 HydrophobicContact CG2-CD1 3.75Å; W463-L472 HydrophobicContact CE3-CD1 4.11Å; W463-L472 HydrophobicContact CZ3-CD1 3.85Å; W463-L472 HydrophobicContact CZ3-CD2 4.49Å; W463-L472 HydrophobicContact CZ3-CG 4.09Å; W469-L472 HydrophobicContact CB-CD1 4.28Å; W469-L472 HydrophobicContact CB-CG 4.21Å; W469-L472 PolarHBondContact O-N 3.44Å; P470-L472 VanDerWaalsContact C-N 3.31Å; P470-L472 PolarHBondContact O-N 3.49Å; L472-L476 VanDerWaalsContact O-CB 3.24Å; L472-L476 WeakPolarHBondContact O-CB 3.48Å; L472-L476 PolarHBondContact O-N 3.08Å
473Q98.8Very high98.1Very high3 Ų314.2 Ų14.21%0.0147%0.07CC..Hα-helixtrans-62.8-47.8174.6-54.2-44.3-67.700110.6V452 W469 P470 L476 I477 W499V452-Q473 PolarHBondContact O-NE2 3.15Å; W469-Q473 WeakPolarHBondContact O-CG 3.34Å; W469-Q473 PolarHBondContact O-N 3.47Å; W469-Q473 VanDerWaalsContact O-N 3.11Å; P470-Q473 PolarHBondContact O-N 3.38Å; Q473-L476 PolarHBondContact O-N 3.01Å; Q473-I477 HydrophobicContact CB-CD1 4.42Å; Q473-I477 WeakPolarHBondContact O-CB 3.37Å; Q473-I477 WeakPolarHBondContact O-CD1 3.43Å; Q473-I477 WeakPolarHBondContact O-CG1 3.48Å; Q473-I477 PolarHBondContact O-N 3.26Å; Q473-W499 HydrophobicContact CB-CD2 4.05Å; Q473-W499 HydrophobicContact CB-CE3 4.49Å; Q473-W499 HydrophobicContact CB-CG 4.24Å; Q473-W499 HydrophobicContact CG-CD2 3.61Å; Q473-W499 HydrophobicContact CG-CE3 3.61Å; Q473-W499 HydrophobicContact CG-CG 4.28Å; Q473-W499 HydrophobicContact CG-CH2 3.8Å; Q473-W499 HydrophobicContact CG-CZ2 3.85Å; Q473-W499 HydrophobicContact CG-CZ3 3.69Å
474H98.8Very high97.9Very high5 Ų518.7 Ų18.72%0.02310%0.102CC..Hα-helixtrans-61.1-50.1179.8-178.3-93.8000111.9W178 P470 P471 L476 I477 E478 V543 Q546W178-H474 AromaticContact CD1-CG 3.99Å; W178-H474 AromaticContact CD1-ND1 3.95Å; W178-H474 AromaticContact NE1-CG 3.59Å; W178-H474 AromaticContact NE1-ND1 3.35Å; W178-H474 PolarHBondContact NE1-ND1 3.29Å; P470-H474 WeakPolarHBondContact O-CB 3.31Å; P470-H474 PolarHBondContact O-N 3.32Å; P471-H474 PolarHBondContact O-N 3.32Å; H474-L476 VanDerWaalsContact C-N 3.28Å; H474-L476 PolarHBondContact O-N 3.41Å; H474-I477 PolarHBondContact O-N 3.36Å; H474-E478 IonicContact CE1-OE2 3.98Å; H474-E478 PolarHBondContact CE1-OE2 3.47Å; H474-E478 IonicContact ND1-OE2 3.04Å; H474-E478 WeakPolarHBondContact O-CB 3.49Å; H474-E478 PolarHBondContact O-N 3.04Å; H474-V543 HydrophobicContact CB-CB 4.45Å; H474-V543 HydrophobicContact CB-CG1 3.91Å; H474-V543 HydrophobicContact CB-CG2 3.73Å; H474-Q546 PolarHBondContact NE2-OE1 2.95Å
475M98.7Very high97.8Very high23 Ų2320 Ų2011%0.11311%0.111CC..Hα-helixtrans-58.8-42.5179-71170.771.400111.4W178 F225 A420 W423 P471 G479W178-M475 HydrophobicContact CZ2-CG 4.33Å; W178-M475 HydrophobicContact CZ2-SD 4.31Å; F225-M475 HydrophobicContact CZ-SD 4.44Å; A420-M475 HydrophobicContact CB-CE 4.18Å; W423-M475 HydrophobicContact CB-CB 4.27Å; W423-M475 WeakPolarHBondContact CB-O 3.24Å; W423-M475 HydrophobicContact CD2-CB 4.25Å; W423-M475 HydrophobicContact CD2-CE 3.81Å; W423-M475 HydrophobicContact CD2-CG 3.94Å; W423-M475 HydrophobicContact CE3-CE 3.47Å; W423-M475 VanDerWaalsContact CE3-CE 3.47Å; W423-M475 HydrophobicContact CG-CB 3.88Å; W423-M475 HydrophobicContact CG-CE 4.41Å; W423-M475 HydrophobicContact CG-CG 4.09Å; W423-M475 HydrophobicContact CH2-CE 4.3Å; W423-M475 HydrophobicContact CZ2-CG 4.31Å; W423-M475 HydrophobicContact CZ3-CE 3.74Å; P471-M475 WeakPolarHBondContact O-CB 2.95Å; P471-M475 VanDerWaalsContact O-CG 3.25Å; P471-M475 WeakPolarHBondContact O-CG 3.27Å; P471-M475 PolarHBondContact O-N 3.35Å; M475-G479 PolarHBondContact O-N 3.24Å
476L98.6Very high97.7Very high13 Ų1323.5 Ų23.57%0.06813%0.13CC..Hα-helixtrans-63.3-52177.6-177.360.2000112L419 L440 V452 L472 Q473 H474 G479 L480 L495L419-L476 HydrophobicContact CB-CD1 4.28Å; L419-L476 HydrophobicContact CD1-CD1 3.68Å; L419-L476 HydrophobicContact CG-CD1 4.5Å; L440-L476 HydrophobicContact CD2-CD1 3.84Å; L440-L476 HydrophobicContact CD2-CD2 4.32Å; L440-L476 HydrophobicContact CD2-CG 4.47Å; V452-L476 HydrophobicContact CB-CD2 3.88Å; V452-L476 HydrophobicContact CG1-CD2 4.04Å; V452-L476 HydrophobicContact CG2-CD2 3.58Å; L472-L476 VanDerWaalsContact O-CB 3.24Å; L472-L476 WeakPolarHBondContact O-CB 3.48Å; L472-L476 PolarHBondContact O-N 3.08Å; Q473-L476 PolarHBondContact O-N 3.01Å; H474-L476 VanDerWaalsContact C-N 3.28Å; H474-L476 PolarHBondContact O-N 3.41Å; L476-G479 PolarHBondContact O-N 3.24Å; L476-L480 HydrophobicContact CD1-CD1 4.06Å; L476-L480 HydrophobicContact CD1-CG 4.28Å; L476-L480 HydrophobicContact CG-CD1 4.11Å; L476-L480 WeakPolarHBondContact O-CB 3.38Å; L476-L480 VanDerWaalsContact O-CG 3.22Å; L476-L480 WeakPolarHBondContact O-CG 3.42Å; L476-L480 PolarHBondContact O-N 2.83Å; L476-L495 HydrophobicContact CD2-CD1 3.93Å; L476-L495 HydrophobicContact CG-CD1 4.18Å
477I98.9Very high97.7Very high1 Ų126.2 Ų26.21%0.00514%0.14CC..Hα-helixtrans-61.2-50.1-179.9-68.9161.1000110.6Q473 H474 G479 L480 S481 A492 L495 A496 L547 Y551Q473-I477 HydrophobicContact CB-CD1 4.42Å; Q473-I477 WeakPolarHBondContact O-CB 3.37Å; Q473-I477 WeakPolarHBondContact O-CD1 3.43Å; Q473-I477 WeakPolarHBondContact O-CG1 3.48Å; Q473-I477 PolarHBondContact O-N 3.26Å; H474-I477 PolarHBondContact O-N 3.36Å; I477-G479 PolarHBondContact O-N 3.46Å; I477-L480 PolarHBondContact O-N 3.22Å; I477-S481 WeakPolarHBondContact O-CB 3.22Å; I477-S481 PolarHBondContact O-N 2.84Å; I477-A492 HydrophobicContact CG2-CB 4.32Å; I477-A492 WeakPolarHBondContact O-CB 3.31Å; I477-L495 HydrophobicContact CD1-CB 4.18Å; I477-L495 HydrophobicContact CG1-CB 3.7Å; I477-A496 HydrophobicContact CD1-CB 4.27Å; I477-A496 HydrophobicContact CG2-CB 4.16Å; I477-L547 HydrophobicContact CB-CD2 4.35Å; I477-L547 HydrophobicContact CD1-CD1 3.93Å; I477-L547 HydrophobicContact CD1-CD2 4.12Å; I477-L547 HydrophobicContact CG2-CD2 3.7Å; I477-Y551 HydrophobicContact CG2-CE2 3.92Å
478E98.5Very high97.7Very high23 Ų2326.1 Ų26.111%0.10714%0.139CC..Hα-helixtrans-62-44-179.5-174.8-167.4167.100110.6W423 H474 S481 K482W423-E478 VanDerWaalsContact CD1-OE2 3.31Å; W423-E478 PolarHBondContact NE1-OE2 3.09Å; H474-E478 IonicContact CE1-OE2 3.98Å; H474-E478 PolarHBondContact CE1-OE2 3.47Å; H474-E478 IonicContact ND1-OE2 3.04Å; H474-E478 WeakPolarHBondContact O-CB 3.49Å; H474-E478 PolarHBondContact O-N 3.04Å; E478-S481 PolarHBondContact O-N 2.67Å; E478-S481 PolarHBondContact O-OG 2.85Å; E478-K482 WeakPolarHBondContact O-CG 3.44Å; E478-K482 PolarHBondContact O-N 2.83Å; E478-K482 WeakPolarHBondContact OE1-CE 3.37Å; E478-K482 IonicContact OE1-NZ 3.78Å; E478-K482 PolarHBondContact OE1-NZ 3.15Å
479G98.2Very high97.7Very high2 Ų230 Ų302%0.02116%0.156CC..Hα-helixtrans-60.3-48.5176.600000112.7M475 L476 I477 S481 K482M475-G479 PolarHBondContact O-N 3.24Å; L476-G479 PolarHBondContact O-N 3.24Å; I477-G479 PolarHBondContact O-N 3.46Å; G479-S481 VanDerWaalsContact C-N 3.3Å; G479-S481 PolarHBondContact O-N 2.92Å; G479-K482 PolarHBondContact O-N 2.84Å
480L98.6Very high97.7Very high3 Ų336.6 Ų36.62%0.01619%0.185CC..Hα-helixtrans-62.9-36.2176.9-70175.1000112.3L437 L440 L476 I477 K482 L483 G488 L491 A492 L495L437-L480 HydrophobicContact CB-CD2 4.43Å; L437-L480 HydrophobicContact CD1-CD2 3.94Å; L440-L480 HydrophobicContact CD2-CD1 3.96Å; L476-L480 HydrophobicContact CD1-CD1 4.06Å; L476-L480 HydrophobicContact CD1-CG 4.28Å; L476-L480 HydrophobicContact CG-CD1 4.11Å; L476-L480 WeakPolarHBondContact O-CB 3.38Å; L476-L480 VanDerWaalsContact O-CG 3.22Å; L476-L480 WeakPolarHBondContact O-CG 3.42Å; L476-L480 PolarHBondContact O-N 2.83Å; I477-L480 PolarHBondContact O-N 3.22Å; L480-K482 PolarHBondContact O-N 3.39Å; L480-L483 HydrophobicContact CD2-CD1 3.8Å; L480-L483 WeakPolarHBondContact O-CB 3.1Å; L480-L483 PolarHBondContact O-N 3.3Å; L480-L483 VanDerWaalsContact O-N 3.15Å; L480-G488 CarbonylContact O-C 3.41Å; L480-L491 HydrophobicContact CD1-CD2 3.94Å; L480-L491 HydrophobicContact CD1-CG 4.01Å; L480-A492 HydrophobicContact CB-CB 3.76Å; L480-L495 HydrophobicContact CD1-CD1 3.84Å
481S98.1Very high97.8Very high27 Ų2737.5 Ų37.519%0.18919%0.189CC..Hα-helixtrans-65.1-22.2178.879.70000113.7I477 E478 G479 Y551I477-S481 WeakPolarHBondContact O-CB 3.22Å; I477-S481 PolarHBondContact O-N 2.84Å; E478-S481 PolarHBondContact O-N 2.67Å; E478-S481 PolarHBondContact O-OG 2.85Å; G479-S481 VanDerWaalsContact C-N 3.3Å; G479-S481 PolarHBondContact O-N 2.92Å; S481-Y551 WeakPolarHBondContact CB-OH 3.33Å
482K96.3Very high97.8Very high81 Ų8137.5 Ų37.535%0.35219%0.189SC..THydrogen-bonded Turntrans-91.3-5.7178.8-66.9174.7-174.5173.40113.2Q425 E478 G479 L480Q425-K482 HydrophobicContact CG-CD 4.45Å; E478-K482 WeakPolarHBondContact O-CG 3.44Å; E478-K482 PolarHBondContact O-N 2.83Å; E478-K482 WeakPolarHBondContact OE1-CE 3.37Å; E478-K482 IonicContact OE1-NZ 3.78Å; E478-K482 PolarHBondContact OE1-NZ 3.15Å; G479-K482 PolarHBondContact O-N 2.84Å; L480-K482 PolarHBondContact O-N 3.39Å
483L96.2Very high97.8Very high10 Ų1039 Ų395%0.05220%0.196CC..SBendtrans-65.6148.8171.6-66.6-179.4000110.6V422 L437 L480 S485 K489V422-L483 HydrophobicContact CG1-CD2 3.87Å; V422-L483 HydrophobicContact CG1-CG 4.24Å; L437-L483 HydrophobicContact CB-CD1 4.01Å; L437-L483 HydrophobicContact CD2-CD1 4.22Å; L480-L483 HydrophobicContact CD2-CD1 3.8Å; L480-L483 WeakPolarHBondContact O-CB 3.1Å; L480-L483 PolarHBondContact O-N 3.3Å; L480-L483 VanDerWaalsContact O-N 3.15Å; L483-S485 VanDerWaalsContact C-N 3.31Å; L483-K489 VanDerWaalsContact O-CE 3.32Å; L483-K489 WeakPolarHBondContact O-CE 3.44Å
484S93Very high97.7Very high98 Ų9841.9 Ų41.969%0.68521%0.211SC*.SBendtrans-75.8-25.9-179.264.80000111.8
485S95.5Very high97.7Very high26 Ų2641.8 Ų41.818%0.18221%0.211CC..SBendtrans-69.5137.9178.269.60000113.3E434 L483 E487 G488 K489E434-S485 VanDerWaalsContact CD-OG 3.25Å; E434-S485 VanDerWaalsContact OE1-CB 3.3Å; E434-S485 WeakPolarHBondContact OE1-CB 3.12Å; E434-S485 PolarHBondContact OE1-N 2.94Å; E434-S485 PolarHBondContact OE1-OG 3.43Å; E434-S485 WeakPolarHBondContact OE2-CB 3.36Å; E434-S485 PolarHBondContact OE2-OG 2.82Å; L483-S485 VanDerWaalsContact C-N 3.31Å; S485-E487 PolarHBondContact O-N 2.85Å; S485-G488 PolarHBondContact O-N 2.93Å; S485-G488 PolarHBondContact OG-N 3.39Å; S485-G488 VanDerWaalsContact OG-N 3.09Å; S485-K489 PolarHBondContact O-N 2.94Å
486E97Very high97.7Very high135 Ų13540.7 Ų40.763%0.63121%0.206SC*.Hα-helixtrans-63.1-26.1170.2-67.3-55.5124.500111.8K489 K490E486-K489 IonicContact OE1-NZ 2.63Å; E486-K489 PolarHBondContact OE1-NZ 3.09Å; E486-K490 VanDerWaalsContact O-CB 3.23Å; E486-K490 WeakPolarHBondContact O-CB 3.33Å; E486-K490 PolarHBondContact O-N 3.22Å
487E97.4Very high97.7Very high88 Ų8841.8 Ų41.841%0.41121%0.21SC..Hα-helixtrans-63.8-47.6173.4-172.7173.9-147.900111.7L437 Q438 K441 S485 K490 L491L437-E487 HydrophobicContact CD2-CB 4.26Å; L437-E487 HydrophobicContact CD2-CG 4.11Å; Q438-E487 PolarHBondContact NE2-OE2 3.31Å; K441-E487 WeakPolarHBondContact CE-OE1 3.28Å; K441-E487 IonicContact NZ-OE1 2.65Å; K441-E487 PolarHBondContact NZ-OE1 3.06Å; K441-E487 IonicContact NZ-OE2 2.74Å; S485-E487 PolarHBondContact O-N 2.85Å; E487-K490 PolarHBondContact O-N 2.64Å; E487-L491 PolarHBondContact O-N 2.89Å
488G97.9Very high97.6Very high0 Ų045.1 Ų45.10%022%0.223CC..Hα-helixtrans-60.9-46.6176.700000112.3L480 S485 K490 L491 A492L480-G488 CarbonylContact O-C 3.41Å; S485-G488 PolarHBondContact O-N 2.93Å; S485-G488 PolarHBondContact OG-N 3.39Å; S485-G488 VanDerWaalsContact OG-N 3.09Å; G488-K490 PolarHBondContact O-N 3.29Å; G488-L491 PolarHBondContact O-N 3.45Å; G488-A492 WeakPolarHBondContact O-CB 3.49Å; G488-A492 PolarHBondContact O-N 2.96Å
489K98.3Very high97.6Very high81 Ų8144 Ų4435%0.35222%0.218SC..Hα-helixtrans-62.5-40.6177.4-64.2176-163.6161.90112.7L483 S485 E486 A492 F493L483-K489 VanDerWaalsContact O-CE 3.32Å; L483-K489 WeakPolarHBondContact O-CE 3.44Å; S485-K489 PolarHBondContact O-N 2.94Å; E486-K489 IonicContact OE1-NZ 2.63Å; E486-K489 PolarHBondContact OE1-NZ 3.09Å; K489-A492 WeakPolarHBondContact O-CB 3.35Å; K489-A492 PolarHBondContact O-N 3.01Å; K489-F493 PolarHBondContact O-N 3.39Å; K489-F493 VanDerWaalsContact O-N 3.09Å
490K98.4Very high97.6Very high140 Ų14044 Ų4461%0.60922%0.217SC*.Hα-helixtrans-64.5-45.4176.5-177179.8176.5-175.40111.2E486 E487 G488 A492 F493 D494E486-K490 VanDerWaalsContact O-CB 3.23Å; E486-K490 WeakPolarHBondContact O-CB 3.33Å; E486-K490 PolarHBondContact O-N 3.22Å; E487-K490 PolarHBondContact O-N 2.64Å; G488-K490 PolarHBondContact O-N 3.29Å; K490-A492 VanDerWaalsContact C-N 3.31Å; K490-A492 PolarHBondContact O-N 2.77Å; K490-F493 PolarHBondContact O-N 3.4Å; K490-D494 PolarHBondContact O-N 3.39Å
491L98.5Very high97.5Very high19 Ų1947 Ų4710%0.09923%0.23CC..Hα-helixtrans-63.2-39.4177.1-178.560.1000111.6L437 L440 K441 L446 L480 E487 G488 F493 D494 L495L437-L491 HydrophobicContact CD1-CB 4.48Å; L437-L491 HydrophobicContact CD1-CD2 3.43Å; L437-L491 VanDerWaalsContact CD1-CD2 3.43Å; L440-L491 HydrophobicContact CD2-CD2 3.98Å; K441-L491 HydrophobicContact CG-CD2 4.45Å; L446-L491 HydrophobicContact CD1-CD1 3.96Å; L446-L491 HydrophobicContact CD1-CD2 3.88Å; L446-L491 HydrophobicContact CD2-CD1 4.4Å; L480-L491 HydrophobicContact CD1-CD2 3.94Å; L480-L491 HydrophobicContact CD1-CG 4.01Å; E487-L491 PolarHBondContact O-N 2.89Å; G488-L491 PolarHBondContact O-N 3.45Å; L491-F493 VanDerWaalsContact C-N 3.34Å; L491-F493 PolarHBondContact O-N 3.01Å; L491-D494 PolarHBondContact O-N 3.28Å; L491-L495 HydrophobicContact CD1-CD1 4.37Å; L491-L495 HydrophobicContact CD1-CG 4.14Å; L491-L495 HydrophobicContact CG-CD1 4.18Å; L491-L495 HydrophobicContact CG-CG 4.39Å; L491-L495 WeakPolarHBondContact O-CB 3.46Å; L491-L495 WeakPolarHBondContact O-CG 3.26Å; L491-L495 PolarHBondContact O-N 3Å
492A98.8Very high97.4Very high0 Ų045.8 Ų45.80%022%0.221CC..Hα-helixtrans-56.3-48.1174.100000111.6I477 L480 G488 K489 K490 L495 A496I477-A492 HydrophobicContact CG2-CB 4.32Å; I477-A492 WeakPolarHBondContact O-CB 3.31Å; L480-A492 HydrophobicContact CB-CB 3.76Å; G488-A492 WeakPolarHBondContact O-CB 3.49Å; G488-A492 PolarHBondContact O-N 2.96Å; K489-A492 WeakPolarHBondContact O-CB 3.35Å; K489-A492 PolarHBondContact O-N 3.01Å; K490-A492 VanDerWaalsContact C-N 3.31Å; K490-A492 PolarHBondContact O-N 2.77Å; A492-L495 PolarHBondContact O-N 3.01Å; A492-A496 WeakPolarHBondContact O-CB 3.29Å; A492-A496 PolarHBondContact O-N 3.46Å
493F98.6Very high97.4Very high42 Ų4242 Ų4218%0.18421%0.205CC..Hα-helixtrans-63.4-44.6176.1175-102.2000112.5K489 K490 L491 L495 A496 Q497 Y551 T554 L555K489-F493 PolarHBondContact O-N 3.39Å; K489-F493 VanDerWaalsContact O-N 3.09Å; K490-F493 PolarHBondContact O-N 3.4Å; L491-F493 VanDerWaalsContact C-N 3.34Å; L491-F493 PolarHBondContact O-N 3.01Å; F493-L495 VanDerWaalsContact C-N 3.27Å; F493-L495 PolarHBondContact O-N 2.65Å; F493-A496 WeakPolarHBondContact O-CB 3.4Å; F493-A496 PolarHBondContact O-N 2.87Å; F493-Q497 WeakPolarHBondContact O-CB 3.49Å; F493-Q497 PolarHBondContact O-N 3.01Å; F493-Y551 HydrophobicContact CB-CE1 4.26Å; F493-Y551 AromaticContact CD2-CD1 3.69Å; F493-Y551 HydrophobicContact CD2-CD1 3.69Å; F493-Y551 HydrophobicContact CD2-CE1 4.2Å; F493-Y551 HydrophobicContact CD2-CG 4.11Å; F493-Y551 HydrophobicContact CE2-CD1 4.48Å; F493-T554 WeakPolarHBondContact CE2-OG1 3.47Å; F493-L555 HydrophobicContact CE2-CD2 4.18Å; F493-L555 HydrophobicContact CE2-CG 4.45Å
494D98.3Very high97.4Very high63 Ų6343.2 Ų43.234%0.33721%0.209SC..Hα-helixtrans-59.9-40.2179-74.1-18.1000111.3K490 L491 R498K490-D494 PolarHBondContact O-N 3.39Å; L491-D494 PolarHBondContact O-N 3.28Å; D494-R498 WeakPolarHBondContact O-CG 3.42Å; D494-R498 PolarHBondContact O-N 3.23Å
495L98.6Very high97.4Very high3 Ų343.9 Ų43.92%0.01620%0.196CC..Hα-helixtrans-68.6-42175-71.7178.6000112.2L446 V452 L476 I477 L480 L491 A492 F493 Q497 R498 W499L446-L495 HydrophobicContact CD2-CD1 4.31Å; L446-L495 HydrophobicContact CD2-CD2 4.05Å; V452-L495 HydrophobicContact CG2-CD1 4.3Å; V452-L495 HydrophobicContact CG2-CD2 3.79Å; L476-L495 HydrophobicContact CD2-CD1 3.93Å; L476-L495 HydrophobicContact CG-CD1 4.18Å; I477-L495 HydrophobicContact CD1-CB 4.18Å; I477-L495 HydrophobicContact CG1-CB 3.7Å; L480-L495 HydrophobicContact CD1-CD1 3.84Å; L491-L495 HydrophobicContact CD1-CD1 4.37Å; L491-L495 HydrophobicContact CD1-CG 4.14Å; L491-L495 HydrophobicContact CG-CD1 4.18Å; L491-L495 HydrophobicContact CG-CG 4.39Å; L491-L495 WeakPolarHBondContact O-CB 3.46Å; L491-L495 WeakPolarHBondContact O-CG 3.26Å; L491-L495 PolarHBondContact O-N 3Å; A492-L495 PolarHBondContact O-N 3.01Å; F493-L495 VanDerWaalsContact C-N 3.27Å; F493-L495 PolarHBondContact O-N 2.65Å; L495-Q497 VanDerWaalsContact C-N 3.33Å; L495-Q497 PolarHBondContact O-N 2.91Å; L495-R498 PolarHBondContact O-N 2.84Å; L495-W499 WeakPolarHBondContact O-CB 3.49Å; L495-W499 PolarHBondContact O-N 3.36Å
496A98.7Very high97.3Very high0 Ų042.7 Ų42.70%019%0.188CC..Hα-helixtrans-59.2-43.9173.700000111.8I477 A492 F493 W499 I500 L547 Y551I477-A496 HydrophobicContact CD1-CB 4.27Å; I477-A496 HydrophobicContact CG2-CB 4.16Å; A492-A496 WeakPolarHBondContact O-CB 3.29Å; A492-A496 PolarHBondContact O-N 3.46Å; F493-A496 WeakPolarHBondContact O-CB 3.4Å; F493-A496 PolarHBondContact O-N 2.87Å; A496-W499 PolarHBondContact O-N 3.22Å; A496-I500 WeakPolarHBondContact O-CB 3.32Å; A496-I500 WeakPolarHBondContact O-CG1 3.44Å; A496-I500 PolarHBondContact O-N 2.89Å; A496-L547 HydrophobicContact CB-CD2 4.18Å; A496-Y551 HydrophobicContact CB-CD2 3.61Å; A496-Y551 HydrophobicContact CB-CE2 3.73Å; A496-Y551 HydrophobicContact CB-CG 4.4Å
497Q98.2Very high97.1Very high35 Ų3537.8 Ų37.816%0.16416%0.164CC..Hα-helixtrans-63.6-40.3177176.961.492.200112.3F493 L495 K501 L555 T556F493-Q497 WeakPolarHBondContact O-CB 3.49Å; F493-Q497 PolarHBondContact O-N 3.01Å; L495-Q497 VanDerWaalsContact C-N 3.33Å; L495-Q497 PolarHBondContact O-N 2.91Å; Q497-K501 WeakPolarHBondContact O-CB 3.37Å; Q497-K501 PolarHBondContact O-N 3Å; Q497-L555 HydrophobicContact CB-CD2 3.95Å; Q497-T556 PolarHBondContact NE2-O 3.04Å; Q497-T556 PolarHBondContact OE1-O 3.4Å; Q497-T556 PolarHBondContact OE1-OG1 3.27Å
498R96.9Very high96.9Very high72 Ų7238.7 Ų38.727%0.27217%0.168SC..Hα-helixtrans-64.2-49.1173.9-73.2-177.3-140.3-173.75.4111.5L446 F448 D494 L495 K501 T502L446-R498 PolarHBondContact O-NH1 3.32Å; F448-R498 PolarHBondContact O-NH1 2.85Å; D494-R498 WeakPolarHBondContact O-CG 3.42Å; D494-R498 PolarHBondContact O-N 3.23Å; L495-R498 PolarHBondContact O-N 2.84Å; R498-K501 PolarHBondContact O-N 3.42Å; R498-T502 WeakPolarHBondContact O-CB 3.41Å; R498-T502 PolarHBondContact O-N 3.44Å; R498-T502 PolarHBondContact O-OG1 3.22Å
499W98Very high96.6Very high0 Ų043.9 Ų43.90%019%0.192CC..Hα-helixtrans-64.7-50-175.7-172.8-112.2000112.5A468 P470 Q473 L495 A496 K501 T502 N503 Y517 L547A468-W499 HydrophobicContact CB-CH2 4.26Å; A468-W499 HydrophobicContact CB-CZ3 3.84Å; P470-W499 HydrophobicContact CB-CZ2 3.98Å; P470-W499 HydrophobicContact CG-CZ2 3.85Å; Q473-W499 HydrophobicContact CB-CD2 4.05Å; Q473-W499 HydrophobicContact CB-CE3 4.49Å; Q473-W499 HydrophobicContact CB-CG 4.24Å; Q473-W499 HydrophobicContact CG-CD2 3.61Å; Q473-W499 HydrophobicContact CG-CE3 3.61Å; Q473-W499 HydrophobicContact CG-CG 4.28Å; Q473-W499 HydrophobicContact CG-CH2 3.8Å; Q473-W499 HydrophobicContact CG-CZ2 3.85Å; Q473-W499 HydrophobicContact CG-CZ3 3.69Å; L495-W499 WeakPolarHBondContact O-CB 3.49Å; L495-W499 PolarHBondContact O-N 3.36Å; A496-W499 PolarHBondContact O-N 3.22Å; W499-K501 VanDerWaalsContact C-N 3.3Å; W499-K501 PolarHBondContact O-N 2.81Å; W499-T502 VanDerWaalsContact O-CB 3.29Å; W499-T502 WeakPolarHBondContact O-CB 3.46Å; W499-T502 PolarHBondContact O-N 2.72Å; W499-T502 VanDerWaalsContact O-N 3.09Å; W499-N503 VanDerWaalsContact CD1-OD1 3.29Å; W499-N503 PolarHBondContact NE1-OD1 3.11Å; W499-N503 PolarHBondContact O-N 2.84Å; W499-N503 PolarHBondContact O-OD1 3.39Å; W499-Y517 AromaticContact CH2-CD2 3.55Å; W499-Y517 HydrophobicContact CH2-CD2 3.55Å; W499-Y517 HydrophobicContact CH2-CE2 4.37Å; W499-Y517 HydrophobicContact CH2-CG 4.09Å; W499-Y517 AromaticContact CZ2-CD2 3.98Å; W499-Y517 HydrophobicContact CZ2-CD2 3.98Å; W499-Y517 HydrophobicContact CZ2-CE2 4.37Å; W499-Y517 HydrophobicContact CZ3-CD2 4.35Å; W499-Y517 HydrophobicContact CZ3-CG 4.47Å; W499-L547 HydrophobicContact CG-CD1 4.49Å
500I98.1Very high96.2Very high0 Ų044.4 Ų44.40%019%0.193CC..Hα-helixtrans-60.6-40.9177.6-72.3-59000111.6L123 W126 A496 T502 N503 W504 A544 L547 L548 L555L123-I500 HydrophobicContact CD1-CG2 4.12Å; L123-I500 HydrophobicContact CD2-CG2 4.04Å; W126-I500 HydrophobicContact CH2-CD1 4.38Å; W126-I500 HydrophobicContact CZ3-CD1 4.21Å; W126-I500 HydrophobicContact CZ3-CG2 3.98Å; A496-I500 WeakPolarHBondContact O-CB 3.32Å; A496-I500 WeakPolarHBondContact O-CG1 3.44Å; A496-I500 PolarHBondContact O-N 2.89Å; I500-T502 VanDerWaalsContact C-N 3.3Å; I500-T502 PolarHBondContact O-N 2.88Å; I500-N503 PolarHBondContact O-N 3.04Å; I500-W504 VanDerWaalsContact O-CB 3.22Å; I500-W504 WeakPolarHBondContact O-CB 3.26Å; I500-W504 PolarHBondContact O-N 2.92Å; I500-A544 HydrophobicContact CD1-CB 4.1Å; I500-L547 HydrophobicContact CD1-CB 3.93Å; I500-L547 HydrophobicContact CD1-CD1 4.36Å; I500-L547 HydrophobicContact CG1-CB 4.01Å; I500-L547 HydrophobicContact CG1-CD1 4.38Å; I500-L548 HydrophobicContact CD1-CG 4.04Å; I500-L548 HydrophobicContact CG2-CD2 4.14Å; I500-L555 HydrophobicContact CB-CD1 4.45Å; I500-L555 HydrophobicContact CG1-CD1 3.98Å; I500-L555 HydrophobicContact CG2-CD1 4.37Å
501K96.3Very high95.8Very high67 Ų6745.8 Ų45.829%0.29120%0.201SC..Hα-helixtrans-65.2-36.6177-174.9176.7179.3-174.90112.2Q497 R498 W499 R505Q497-K501 WeakPolarHBondContact O-CB 3.37Å; Q497-K501 PolarHBondContact O-N 3Å; R498-K501 PolarHBondContact O-N 3.42Å; W499-K501 VanDerWaalsContact C-N 3.3Å; W499-K501 PolarHBondContact O-N 2.81Å; K501-R505 WeakPolarHBondContact O-CB 3.44Å; K501-R505 WeakPolarHBondContact O-CG 3.38Å; K501-R505 PolarHBondContact O-N 3.12Å
502T96.1Very high95.4Very high2 Ų245.7 Ų45.71%0.01220%0.203CC..Hα-helixtrans-63-55.6175.1-59.70000110.2N450 R498 W499 I500 W504 R505 A506 Y517N450-T502 VanDerWaalsContact CA-OG1 3.27Å; N450-T502 WeakPolarHBondContact CA-OG1 3.49Å; N450-T502 HydrophobicContact CB-CG2 3.7Å; N450-T502 WeakPolarHBondContact CB-OG1 3.4Å; N450-T502 PolarHBondContact OD1-OG1 3.2Å; R498-T502 WeakPolarHBondContact O-CB 3.41Å; R498-T502 PolarHBondContact O-N 3.44Å; R498-T502 PolarHBondContact O-OG1 3.22Å; W499-T502 VanDerWaalsContact O-CB 3.29Å; W499-T502 WeakPolarHBondContact O-CB 3.46Å; W499-T502 PolarHBondContact O-N 2.72Å; W499-T502 VanDerWaalsContact O-N 3.09Å; I500-T502 VanDerWaalsContact C-N 3.3Å; I500-T502 PolarHBondContact O-N 2.88Å; T502-W504 VanDerWaalsContact C-N 3.33Å; T502-W504 PolarHBondContact O-N 3.43Å; T502-R505 PolarHBondContact O-N 3.2Å; T502-A506 WeakPolarHBondContact O-CB 3.48Å; T502-A506 PolarHBondContact O-N 2.91Å; T502-Y517 HydrophobicContact CG2-CD1 4.2Å
503N96.6Very high95.2Very high0 Ų045.8 Ų45.80%020%0.204CC..Hα-helixtrans-61.5-42.4-179.4-57.2149.5000111.7W126 W499 I500 Y507 M513 Y517W126-N503 HydrophobicContact CH2-CB 3.67Å; W126-N503 HydrophobicContact CZ2-CB 3.75Å; W499-N503 VanDerWaalsContact CD1-OD1 3.29Å; W499-N503 PolarHBondContact NE1-OD1 3.11Å; W499-N503 PolarHBondContact O-N 2.84Å; W499-N503 PolarHBondContact O-OD1 3.39Å; I500-N503 PolarHBondContact O-N 3.04Å; N503-Y507 VanDerWaalsContact O-CB 3.27Å; N503-Y507 WeakPolarHBondContact O-CB 3.39Å; N503-Y507 PolarHBondContact O-N 3.48Å; N503-M513 HydrophobicContact CB-CE 4.34Å; N503-Y517 VanDerWaalsContact ND2-CE2 3.33Å; N503-Y517 WeakPolarHBondContact ND2-CE2 3.46Å; N503-Y517 VanDerWaalsContact ND2-CZ 3.32Å
504W95.8Very high95Very high37 Ų3744.2 Ų44.214%0.1420%0.197CC..Hα-helixtrans-61-46.6177.1172.564.4000111.8K122 L123 W126 I500 T502 Y507 Q508 S557K122-W504 HydrophobicContact CB-CZ2 4.42Å; K122-W504 HydrophobicContact CD-CZ2 4.12Å; L123-W504 HydrophobicContact CD2-CB 4.25Å; L123-W504 HydrophobicContact CD2-CD2 4.39Å; L123-W504 HydrophobicContact CD2-CG 4.04Å; W126-W504 HydrophobicContact CD2-CB 4.12Å; W126-W504 AromaticContact CD2-CD1 3.86Å; W126-W504 HydrophobicContact CD2-CG 4.4Å; W126-W504 HydrophobicContact CE3-CB 4.1Å; W126-W504 AromaticContact CG-CD1 3.66Å; W126-W504 HydrophobicContact CH2-CB 4.3Å; W126-W504 HydrophobicContact CZ2-CB 4.28Å; W126-W504 HydrophobicContact CZ3-CB 4.21Å; I500-W504 VanDerWaalsContact O-CB 3.22Å; I500-W504 WeakPolarHBondContact O-CB 3.26Å; I500-W504 PolarHBondContact O-N 2.92Å; T502-W504 VanDerWaalsContact C-N 3.33Å; T502-W504 PolarHBondContact O-N 3.43Å; W504-Y507 PolarHBondContact O-N 2.94Å; W504-Q508 HydrophobicContact CD2-CG 4.41Å; W504-Q508 HydrophobicContact CZ2-CG 4.18Å; W504-Q508 VanDerWaalsContact O-CG 3.31Å; W504-Q508 WeakPolarHBondContact O-CG 3.41Å; W504-Q508 PolarHBondContact O-N 2.96Å; W504-S557 WeakPolarHBondContact CZ3-O 3.45Å
505R93.4Very high94.7Very high112 Ų11241.4 Ų41.442%0.42318%0.182SC..Hα-helixtrans-63-48.2178.6-78172.8170.2-165.4-11.4112.3K501 T502 Y507 Q508 E509K501-R505 WeakPolarHBondContact O-CB 3.44Å; K501-R505 WeakPolarHBondContact O-CG 3.38Å; K501-R505 PolarHBondContact O-N 3.12Å; T502-R505 PolarHBondContact O-N 3.2Å; R505-Y507 VanDerWaalsContact C-N 3.25Å; R505-Y507 PolarHBondContact O-N 2.94Å; R505-Q508 PolarHBondContact O-N 3.17Å; R505-Q508 VanDerWaalsContact O-N 3.13Å; R505-E509 WeakPolarHBondContact O-CB 3.48Å; R505-E509 PolarHBondContact O-N 3.02Å
506A93.1Very high94.5Very high1 Ų141.2 Ų41.21%0.00818%0.181CC..Hα-helixtrans-58.9-40.617600000111.1T502 Q508 E509 Y510 Y517T502-A506 WeakPolarHBondContact O-CB 3.48Å; T502-A506 PolarHBondContact O-N 2.91Å; A506-Q508 PolarHBondContact O-N 3.16Å; A506-E509 PolarHBondContact O-N 3.43Å; A506-Y510 HydrophobicContact CB-CD2 4.44Å; A506-Y510 WeakPolarHBondContact O-CB 3.3Å; A506-Y510 VanDerWaalsContact O-CD2 3.31Å; A506-Y510 WeakPolarHBondContact O-CD2 3.48Å; A506-Y510 PolarHBondContact O-N 3.47Å; A506-Y517 HydrophobicContact CB-CD1 4.2Å; A506-Y517 HydrophobicContact CB-CE1 3.66Å
507Y93.4Very high94.5Very high31 Ų3141.2 Ų41.212%0.12218%0.181CC..Hα-helixtrans-65-39.5175.7-170-91.6000112.8W126 Q129 N503 W504 R505 E509 E511 M513W126-Y507 AromaticContact CD1-CD1 3.35Å; W126-Y507 AromaticContact CD1-CE1 3.82Å; W126-Y507 AromaticContact CD1-CG 3.74Å; W126-Y507 AromaticContact NE1-CD1 3.39Å; W126-Y507 AromaticContact NE1-CD2 3.85Å; W126-Y507 AromaticContact NE1-CG 3.23Å; Q129-Y507 HydrophobicContact CB-CE1 4.33Å; N503-Y507 VanDerWaalsContact O-CB 3.27Å; N503-Y507 WeakPolarHBondContact O-CB 3.39Å; N503-Y507 PolarHBondContact O-N 3.48Å; W504-Y507 PolarHBondContact O-N 2.94Å; R505-Y507 VanDerWaalsContact C-N 3.25Å; R505-Y507 PolarHBondContact O-N 2.94Å; Y507-E509 VanDerWaalsContact C-N 3.31Å; Y507-E509 PolarHBondContact O-N 2.02Å; Y507-E511 WeakPolarHBondContact O-CA 3.01Å; Y507-E511 PolarHBondContact O-N 2.94Å; Y507-M513 HydrophobicContact CD2-CG 3.7Å; Y507-M513 HydrophobicContact CD2-SD 3.76Å; Y507-M513 HydrophobicContact CE2-CG 4.05Å; Y507-M513 HydrophobicContact CG-SD 4.37Å
508Q92.6Very high94.4Very high108 Ų10840.6 Ų40.651%0.50518%0.178SC..Hα-helixtrans-67.6-31.7176.3-68-60.8-73.300112.8W504 R505 A506W504-Q508 HydrophobicContact CD2-CG 4.41Å; W504-Q508 HydrophobicContact CZ2-CG 4.18Å; W504-Q508 VanDerWaalsContact O-CG 3.31Å; W504-Q508 WeakPolarHBondContact O-CG 3.41Å; W504-Q508 PolarHBondContact O-N 2.96Å; R505-Q508 PolarHBondContact O-N 3.17Å; R505-Q508 VanDerWaalsContact O-N 3.13Å; A506-Q508 PolarHBondContact O-N 3.16Å
509E92.4Very high94.3Very high108 Ų10837.1 Ų37.151%0.50517%0.166SC..Hα-helixtrans-85-42.8-177.4-175.4172.9172.100112.6R505 A506 Y507R505-E509 WeakPolarHBondContact O-CB 3.48Å; R505-E509 PolarHBondContact O-N 3.02Å; A506-E509 PolarHBondContact O-N 3.43Å; Y507-E509 VanDerWaalsContact C-N 3.31Å; Y507-E509 PolarHBondContact O-N 2.02Å
510Y89.6Confident94.1Very high93 Ų9339.3 Ų39.337%0.36518%0.177SC..Hα-helixtrans-109.9-0.7-171.7-57.9-84.4000113.8A506 A512 F514 K524A506-Y510 HydrophobicContact CB-CD2 4.44Å; A506-Y510 WeakPolarHBondContact O-CB 3.3Å; A506-Y510 VanDerWaalsContact O-CD2 3.31Å; A506-Y510 WeakPolarHBondContact O-CD2 3.48Å; A506-Y510 PolarHBondContact O-N 3.47Å; Y510-A512 PolarHBondContact O-N 2.77Å; Y510-A512 VanDerWaalsContact O-N 3.09Å; Y510-F514 HydrophobicContact CD2-CE2 4.33Å; Y510-F514 HydrophobicContact CD2-CZ 4.49Å; Y510-F514 HydrophobicContact CG-CE2 4.26Å; Y510-F514 HydrophobicContact CG-CZ 4.02Å; Y510-K524 HydrophobicContact CE2-CB 4.44Å
511E89.9Confident93.6Very high168 Ų16842.4 Ų42.479%0.78521%0.209SC*.SBendtrans55.625.5179.6-57.1-171.6142.200114.2Y507Y507-E511 WeakPolarHBondContact O-CA 3.01Å; Y507-E511 PolarHBondContact O-N 2.94Å
512A90.6Very high92.9Very high17 Ų1742.5 Ų42.514%0.1421%0.213CC..SBendtrans-147.9156.9-176.600000112.5Y510 F514 L535Y510-A512 PolarHBondContact O-N 2.77Å; Y510-A512 VanDerWaalsContact O-N 3.09Å; A512-F514 HydrophobicContact CB-CE1 4.43Å; A512-F514 HydrophobicContact CB-CE2 4.26Å; A512-F514 HydrophobicContact CB-CZ 3.95Å; A512-F514 VanDerWaalsContact O-CE2 3.27Å; A512-F514 WeakPolarHBondContact O-CE2 3.29Å; A512-L535 HydrophobicContact CB-CD2 3.9Å
513M94.4Very high92.1Very high2 Ų242.4 Ų42.41%0.0121%0.212CC..  trans-99.7138.1166.8-64.4-69.1-8200108.7W126 I130 L133 N503 Y507 G536 F537 T540 N541 A544W126-M513 HydrophobicContact CZ2-CE 3.96Å; W126-M513 HydrophobicContact CZ2-SD 3.83Å; I130-M513 HydrophobicContact CD1-CE 4.08Å; I130-M513 HydrophobicContact CG1-CE 4.41Å; L133-M513 HydrophobicContact CD1-CG 4.09Å; N503-M513 HydrophobicContact CB-CE 4.34Å; Y507-M513 HydrophobicContact CD2-CG 3.7Å; Y507-M513 HydrophobicContact CD2-SD 3.76Å; Y507-M513 HydrophobicContact CE2-CG 4.05Å; Y507-M513 HydrophobicContact CG-SD 4.37Å; M513-G536 CarbonylContact O-C 3.22Å; M513-G536 PolarHBondContact O-N 3.25Å; M513-F537 PolarHBondContact O-N 3.09Å; M513-T540 HydrophobicContact CE-CG2 3.49Å; M513-T540 VanDerWaalsContact CE-CG2 3.49Å; M513-N541 VanDerWaalsContact CB-OD1 3.27Å; M513-N541 WeakPolarHBondContact CB-OD1 3.39Å; M513-N541 VanDerWaalsContact CG-OD1 3.29Å; M513-N541 WeakPolarHBondContact CG-OD1 3.17Å; M513-A544 HydrophobicContact CE-CB 4.15Å
514F93.8Very high91.7Very high9 Ų946.9 Ų46.94%0.03923%0.232CC..BIsolated β-bridgetrans-109.2156.7-174.1-59.4-85.8000112.2Y510 A512 K516 Y517 P525 V533 L535 T540Y510-F514 HydrophobicContact CD2-CE2 4.33Å; Y510-F514 HydrophobicContact CD2-CZ 4.49Å; Y510-F514 HydrophobicContact CG-CE2 4.26Å; Y510-F514 HydrophobicContact CG-CZ 4.02Å; A512-F514 HydrophobicContact CB-CE1 4.43Å; A512-F514 HydrophobicContact CB-CE2 4.26Å; A512-F514 HydrophobicContact CB-CZ 3.95Å; A512-F514 VanDerWaalsContact O-CE2 3.27Å; A512-F514 WeakPolarHBondContact O-CE2 3.29Å; F514-K516 VanDerWaalsContact C-N 3.31Å; F514-K516 PolarHBondContact O-N 3.01Å; F514-Y517 HydrophobicContact CB-CE1 4.28Å; F514-Y517 HydrophobicContact CB-CE2 4.19Å; F514-Y517 AromaticContact CD2-CE1 3.93Å; F514-Y517 HydrophobicContact CD2-CE1 3.93Å; F514-Y517 PolarHBondContact N-OH 3.11Å; F514-Y517 WeakPolarHBondContact O-CE2 3.12Å; F514-P525 HydrophobicContact CB-CB 4.47Å; F514-P525 HydrophobicContact CD1-CB 3.59Å; F514-P525 HydrophobicContact CD1-CG 3.44Å; F514-P525 VanDerWaalsContact CD1-CG 3.44Å; F514-P525 HydrophobicContact CD2-CB 4.42Å; F514-P525 HydrophobicContact CD2-CG 3.82Å; F514-P525 HydrophobicContact CE1-CB 3.86Å; F514-P525 HydrophobicContact CE1-CG 3.22Å; F514-P525 HydrophobicContact CE2-CG 3.66Å; F514-P525 HydrophobicContact CG-CB 3.89Å; F514-P525 HydrophobicContact CG-CG 3.72Å; F514-P525 HydrophobicContact CZ-CB 4.41Å; F514-P525 HydrophobicContact CZ-CG 3.36Å; F514-V533 HydrophobicContact CB-CG2 4.47Å; F514-V533 HydrophobicContact CD1-CG2 4.28Å; F514-L535 HydrophobicContact CD1-CD2 3.6Å; F514-L535 HydrophobicContact CE1-CD2 3.2Å; F514-L535 HydrophobicContact CZ-CD2 4.05Å; F514-T540 WeakPolarHBondContact O-CB 3.14Å; F514-T540 PolarHBondContact O-OG1 3.47Å
515E92.5Very high91.4Very high4 Ų446.4 Ų46.42%0.01923%0.233CC..SBendtrans-55.5-44.2171.7-179.3-178.8-137.700112.7W469 P470 Y531 Q534 F537 W539W469-E515 HydrophobicContact CE3-CG 4.22Å; W469-E515 HydrophobicContact CH2-CG 3.95Å; W469-E515 HydrophobicContact CZ3-CG 3.44Å; W469-E515 VanDerWaalsContact CZ3-CG 3.44Å; P470-E515 VanDerWaalsContact CD-O 3.22Å; P470-E515 WeakPolarHBondContact CD-O 3.14Å; E515-Y531 PolarHBondContact OE1-OH 3.45Å; E515-Q534 HydrophobicContact CB-CB 4.4Å; E515-Q534 PolarHBondContact N-O 2.77Å; E515-Q534 VanDerWaalsContact N-O 3.15Å; E515-F537 HydrophobicContact CB-CD2 3.58Å; E515-F537 HydrophobicContact CB-CE2 3.69Å; E515-F537 HydrophobicContact CB-CG 4.06Å; E515-F537 HydrophobicContact CB-CZ 4.25Å; E515-F537 HydrophobicContact CG-CD2 4.05Å; E515-F537 HydrophobicContact CG-CE1 4.32Å; E515-F537 HydrophobicContact CG-CE2 3.64Å; E515-F537 HydrophobicContact CG-CZ 3.77Å; E515-W539 HydrophobicContact CG-CZ2 3.79Å; E515-W539 PolarHBondContact O-NE1 3.19Å
516K95.2Very high91.2Very high0 Ų041.4 Ų41.40%022%0.216CC..  trans-151.6158.7-173.167.3-157.3179.4-134.80111.3Q462 W469 F514 G526 G527 V533Q462-K516 HydrophobicContact CB-CD 4.43Å; W469-K516 HydrophobicContact CD2-CB 3.82Å; W469-K516 HydrophobicContact CD2-CD 4.43Å; W469-K516 HydrophobicContact CE3-CB 4.08Å; W469-K516 HydrophobicContact CG-CB 4.28Å; W469-K516 HydrophobicContact CH2-CB 4.41Å; W469-K516 HydrophobicContact CH2-CD 3.53Å; W469-K516 HydrophobicContact CZ2-CB 4.13Å; W469-K516 HydrophobicContact CZ2-CD 3.17Å; W469-K516 HydrophobicContact CZ2-CG 4.27Å; W469-K516 HydrophobicContact CZ3-CB 4.38Å; W469-K516 HydrophobicContact CZ3-CD 4.28Å; F514-K516 VanDerWaalsContact C-N 3.31Å; F514-K516 PolarHBondContact O-N 3.01Å; K516-G526 PolarHBondContact O-N 3.16Å; K516-G527 WeakPolarHBondContact CE-O 3.46Å; K516-V533 HydrophobicContact CG-CG2 4.49Å
517Y96.8Very high91.1Very high0 Ų043 Ų430%023%0.233CC..EExtended strand (participates in β ladder)trans-130.2145.6-172.4-65.2-98.1000111.2N467 A468 W499 T502 N503 A506 F514 G523 T540N467-Y517 CarbonylContact C-O 3.46Å; N467-Y517 WeakPolarHBondContact CA-O 3.46Å; A468-Y517 PolarHBondContact N-O 3.37Å; A468-Y517 PolarHBondContact O-N 3.19Å; W499-Y517 AromaticContact CH2-CD2 3.55Å; W499-Y517 HydrophobicContact CH2-CD2 3.55Å; W499-Y517 HydrophobicContact CH2-CE2 4.37Å; W499-Y517 HydrophobicContact CH2-CG 4.09Å; W499-Y517 AromaticContact CZ2-CD2 3.98Å; W499-Y517 HydrophobicContact CZ2-CD2 3.98Å; W499-Y517 HydrophobicContact CZ2-CE2 4.37Å; W499-Y517 HydrophobicContact CZ3-CD2 4.35Å; W499-Y517 HydrophobicContact CZ3-CG 4.47Å; T502-Y517 HydrophobicContact CG2-CD1 4.2Å; N503-Y517 VanDerWaalsContact ND2-CE2 3.33Å; N503-Y517 WeakPolarHBondContact ND2-CE2 3.46Å; N503-Y517 VanDerWaalsContact ND2-CZ 3.32Å; A506-Y517 HydrophobicContact CB-CD1 4.2Å; A506-Y517 HydrophobicContact CB-CE1 3.66Å; F514-Y517 HydrophobicContact CB-CE1 4.28Å; F514-Y517 HydrophobicContact CB-CE2 4.19Å; F514-Y517 AromaticContact CD2-CE1 3.93Å; F514-Y517 HydrophobicContact CD2-CE1 3.93Å; F514-Y517 PolarHBondContact N-OH 3.11Å; F514-Y517 WeakPolarHBondContact O-CE2 3.12Å; Y517-G523 WeakPolarHBondContact CD1-O 3.39Å; Y517-T540 HydrophobicContact CE2-CG2 3.64Å
518D96.3Very high90.8Very high21 Ų2143.4 Ų43.411%0.11225%0.247CC..EExtended strand (participates in β ladder)trans-73.3127.5170.8-169.5-30.9000109.5N520 K524D518-N520 PolarHBondContact O-N 3.41Å; D518-N520 WeakPolarHBondContact OD1-CA 3.05Å; D518-N520 VanDerWaalsContact OD1-CB 3.27Å; D518-N520 WeakPolarHBondContact OD1-CB 3.45Å; D518-N520 PolarHBondContact OD1-N 2.89Å; D518-N520 PolarHBondContact OD1-ND2 3.04Å; D518-N520 VanDerWaalsContact OD1-ND2 3.12Å; D518-K524 HydrophobicContact CB-CG 4.01Å; D518-K524 PolarHBondContact N-O 2.89Å; D518-K524 VanDerWaalsContact OD2-CE 3.27Å; D518-K524 WeakPolarHBondContact OD2-CE 3.29Å
519V96.3Very high90.5Very high0 Ų039.8 Ų39.80%024%0.238CC..SBendtrans-70.2-15.2179.2-62.20000113.4F448 P449 N450 P453 Y465 P466 A468F448-V519 HydrophobicContact CB-CB 3.79Å; F448-V519 HydrophobicContact CB-CG2 3.91Å; F448-V519 HydrophobicContact CD1-CB 4.35Å; F448-V519 HydrophobicContact CD1-CG2 3.53Å; F448-V519 HydrophobicContact CD2-CG2 4.28Å; F448-V519 HydrophobicContact CE1-CG2 4.13Å; F448-V519 HydrophobicContact CG-CB 4.07Å; F448-V519 HydrophobicContact CG-CG2 3.62Å; P449-V519 WeakPolarHBondContact CD-O 3.42Å; P449-V519 WeakPolarHBondContact CG-O 3.21Å; N450-V519 WeakPolarHBondContact CB-O 3.46Å; N450-V519 PolarHBondContact N-O 2.8Å; P453-V519 HydrophobicContact CB-CG1 3.86Å; P453-V519 HydrophobicContact CB-CG2 4.01Å; P453-V519 HydrophobicContact CG-CG2 4.4Å; Y465-V519 HydrophobicContact CD2-CG2 4.27Å; Y465-V519 HydrophobicContact CE2-CG2 4.03Å; P466-V519 HydrophobicContact CB-CG2 4.46Å; P466-V519 WeakPolarHBondContact O-CG2 3.4Å; P466-V519 PolarHBondContact O-N 3.29Å; A468-V519 HydrophobicContact CB-CG1 3.38Å
520N93.4Very high89.8Confident46 Ų4637 Ų3725%0.24623%0.226CC..SBendtrans-96.1172.2-179.8-55.8-70.5000112.3F448 N450 Y465 P466 D518 D522 G523F448-N520 WeakPolarHBondContact CD1-OD1 3.21Å; N450-N520 PolarHBondContact ND2-O 2.86Å; Y465-N520 PolarHBondContact OH-ND2 3.4Å; P466-N520 WeakPolarHBondContact CB-ND2 3.38Å; D518-N520 PolarHBondContact O-N 3.41Å; D518-N520 WeakPolarHBondContact OD1-CA 3.05Å; D518-N520 VanDerWaalsContact OD1-CB 3.27Å; D518-N520 WeakPolarHBondContact OD1-CB 3.45Å; D518-N520 PolarHBondContact OD1-N 2.89Å; D518-N520 PolarHBondContact OD1-ND2 3.04Å; D518-N520 VanDerWaalsContact OD1-ND2 3.12Å; N520-D522 PolarHBondContact O-N 3.05Å; N520-G523 PolarHBondContact O-N 2.98Å
521G86.6Confident89.4Confident65 Ų6534.6 Ų34.667%0.6722%0.216SC*.THydrogen-bonded Turntrans60.3-131.4170.500000113.4N450N450-G521 PolarHBondContact ND2-O 2.83Å
522D82.1Confident88.8Confident68 Ų6834.3 Ų34.336%0.36422%0.215SC..THydrogen-bonded Turntrans-87.3-6.1-178.453.86.4000114.2N520 K524N520-D522 PolarHBondContact O-N 3.05Å; D522-K524 VanDerWaalsContact OD1-CB 3.31Å; D522-K524 WeakPolarHBondContact OD1-CB 3.19Å; D522-K524 PolarHBondContact OD1-N 2.87Å
523G79.3Confident88.4Confident0 Ų035.4 Ų35.40%022%0.22CC..  trans80.530.2-174.600000112.7N450 Y517 N520N450-G523 WeakPolarHBondContact ND2-CA 3.12Å; N450-G523 PolarHBondContact ND2-N 2.97Å; Y517-G523 WeakPolarHBondContact CD1-O 3.39Å; N520-G523 PolarHBondContact O-N 2.98Å
524K88.9Confident88Confident95 Ų9536.6 Ų36.641%0.41323%0.225SC..  trans-51.2164.1169.866.3177.5-178.2175.90112.5Y510 D518 D522 G526Y510-K524 HydrophobicContact CE2-CB 4.44Å; D518-K524 HydrophobicContact CB-CG 4.01Å; D518-K524 PolarHBondContact N-O 2.89Å; D518-K524 VanDerWaalsContact OD2-CE 3.27Å; D518-K524 WeakPolarHBondContact OD2-CE 3.29Å; D522-K524 VanDerWaalsContact OD1-CB 3.31Å; D522-K524 WeakPolarHBondContact OD1-CB 3.19Å; D522-K524 PolarHBondContact OD1-N 2.87Å; K524-G526 PolarHBondContact O-N 3.1Å
525P89.3Confident87.3Confident27 Ų2740.6 Ų40.618%0.17525%0.246CC..BIsolated β-bridgetrans-52.6134.5174.2-25.536.6000111.2F514 V533F514-P525 HydrophobicContact CB-CB 4.47Å; F514-P525 HydrophobicContact CD1-CB 3.59Å; F514-P525 HydrophobicContact CD1-CG 3.44Å; F514-P525 VanDerWaalsContact CD1-CG 3.44Å; F514-P525 HydrophobicContact CD2-CB 4.42Å; F514-P525 HydrophobicContact CD2-CG 3.82Å; F514-P525 HydrophobicContact CE1-CB 3.86Å; F514-P525 HydrophobicContact CE1-CG 3.22Å; F514-P525 HydrophobicContact CE2-CG 3.66Å; F514-P525 HydrophobicContact CG-CB 3.89Å; F514-P525 HydrophobicContact CG-CG 3.72Å; F514-P525 HydrophobicContact CZ-CB 4.41Å; F514-P525 HydrophobicContact CZ-CG 3.36Å; P525-V533 HydrophobicContact CB-CG1 3.97Å; P525-V533 HydrophobicContact CB-CG2 4.07Å
526G88.7Confident86.7Confident6 Ų641.1 Ų41.16%0.06225%0.253CS..  trans-69.3175.2174.200000112N467 K516 K524 V533N467-G526 WeakPolarHBondContact OD1-CA 3.24Å; K516-G526 PolarHBondContact O-N 3.16Å; K524-G526 PolarHBondContact O-N 3.1Å; G526-V533 WeakPolarHBondContact O-CB 3.42Å
527G91.6Very high86.5Confident36 Ų3641.2 Ų41.237%0.37125%0.253SS..  trans-145.5-160.2-175.100000113.8N467 K516N467-G527 PolarHBondContact ND2-O 3.08Å; N467-G527 PolarHBondContact OD1-N 3.2Å; K516-G527 WeakPolarHBondContact CE-O 3.46Å
528G86.8Confident86.4Confident39 Ų3941.2 Ų41.240%0.40225%0.253SS..  trans77.3174177.900000114.4G460 Q462G460-G528 WeakPolarHBondContact O-CA 3.23Å; Q462-G528 WeakPolarHBondContact CB-O 3.41Å
529G86.2Confident86.4Confident32 Ų3240.4 Ų40.433%0.3325%0.249SC..SBendtrans80.5-159.3-173.300000113.8G460G460-G529 PolarHBondContact O-N 3.02Å
530E78.7Confident86.5Confident50 Ų5040.4 Ų40.423%0.23425%0.249CC..SBendtrans-90-7.1-170.3-60.4179159.200113.7R285 S288 F321R285-E530 IonicContact CZ-OE1 2.61Å; R285-E530 IonicContact CZ-OE2 3.43Å; R285-E530 IonicContact NH1-OE2 3.49Å; R285-E530 PolarHBondContact NH1-OE2 2.82Å; R285-E530 VanDerWaalsContact NH2-CD 3.32Å; R285-E530 IonicContact NH2-OE1 2.84Å; R285-E530 PolarHBondContact NH2-OE1 2.89Å; R285-E530 IonicContact NH2-OE2 3.33Å; R285-E530 PolarHBondContact NH2-OE2 3.09Å; S288-E530 PolarHBondContact OG-OE2 2.84Å; F321-E530 VanDerWaalsContact CE2-OE1 3.26Å; F321-E530 WeakPolarHBondContact CE2-OE1 3.47Å
531Y80.7Confident86.7Confident41 Ų4138.2 Ų38.216%0.16124%0.237CC..SBendtrans-148.4158-176.859.1-94.6000113.5F168 Q462 E515 Q534F168-Y531 HydrophobicContact CE2-CE2 4.24Å; F168-Y531 HydrophobicContact CZ-CE1 4.44Å; F168-Y531 AromaticContact CZ-CE2 3.9Å; F168-Y531 HydrophobicContact CZ-CE2 3.9Å; F168-Y531 AromaticContact CZ-CZ 3.73Å; Q462-Y531 PolarHBondContact NE2-OH 3.11Å; Q462-Y531 PolarHBondContact OE1-OH 2.87Å; E515-Y531 PolarHBondContact OE1-OH 3.45Å; Y531-Q534 HydrophobicContact CD2-CG 4.31Å; Y531-Q534 HydrophobicContact CE2-CG 4.17Å
532E77.6Confident87.2Confident163 Ų16335.1 Ų35.176%0.76221%0.205SC*.PPolyproline II helixtrans-63.9149.9177.7-67.4-62.6156.100112.6Q534E532-Q534 PolarHBondContact O-N 2.82Å; E532-Q534 PolarHBondContact O-NE2 3.18Å
533V80.6Confident88Confident40 Ų4031.9 Ų31.924%0.24219%0.188CC..PPolyproline II helixtrans-58.3137.3-179.466.70000112.7F514 K516 P525 G526F514-V533 HydrophobicContact CB-CG2 4.47Å; F514-V533 HydrophobicContact CD1-CG2 4.28Å; K516-V533 HydrophobicContact CG-CG2 4.49Å; P525-V533 HydrophobicContact CB-CG1 3.97Å; P525-V533 HydrophobicContact CB-CG2 4.07Å; G526-V533 WeakPolarHBondContact O-CB 3.42Å
534Q86.3Confident88.9Confident26 Ų2631.9 Ų31.912%0.12119%0.188CC..PPolyproline II helixtrans-98147.5-175.4-59.1-60.4-55.700113.2R167 F168 E515 Y531 E532 F537R167-Q534 HydrophobicContact CG-CG 4.23Å; F168-Q534 HydrophobicContact CD2-CB 4.46Å; F168-Q534 HydrophobicContact CD2-CG 4.09Å; F168-Q534 HydrophobicContact CE2-CB 4.3Å; F168-Q534 HydrophobicContact CE2-CG 3.66Å; E515-Q534 HydrophobicContact CB-CB 4.4Å; E515-Q534 PolarHBondContact N-O 2.77Å; E515-Q534 VanDerWaalsContact N-O 3.15Å; Y531-Q534 HydrophobicContact CD2-CG 4.31Å; Y531-Q534 HydrophobicContact CE2-CG 4.17Å; E532-Q534 PolarHBondContact O-N 2.82Å; E532-Q534 PolarHBondContact O-NE2 3.18Å; Q534-F537 HydrophobicContact CB-CD2 4.06Å; Q534-F537 HydrophobicContact CB-CE2 4.04Å
535L80.7Confident89.4Confident94 Ų9427.4 Ų27.449%0.49217%0.168SC..BIsolated β-bridgetrans-100.4142.5179.4-55.1178.2000111.4G165 G166 A512 F514G165-L535 CarbonylContact C-O 3.6Å; G165-L535 WeakPolarHBondContact CA-O 3.48Å; G166-L535 PolarHBondContact N-O 3.21Å; A512-L535 HydrophobicContact CB-CD2 3.9Å; F514-L535 HydrophobicContact CD1-CD2 3.6Å; F514-L535 HydrophobicContact CE1-CD2 3.2Å; F514-L535 HydrophobicContact CZ-CD2 4.05Å
536G79.5Confident89.8Confident15 Ų1527.2 Ų27.216%0.15517%0.165CC..SBendtrans158-63.4171.600000112M513 N541M513-G536 CarbonylContact O-C 3.22Å; M513-G536 PolarHBondContact O-N 3.25Å; G536-N541 PolarHBondContact O-ND2 3.12Å; G536-N541 PolarHBondContact O-OD1 3.37Å
537F90.6Very high90.3Very high1 Ų127 Ų270%0.00416%0.162CC..  cis-109.3132.4-44.8-168.2-75.4000107.3P164 F168 M513 E515 Q534 W539 T540 N541P164-F537 HydrophobicContact CB-CD1 4.02Å; P164-F537 HydrophobicContact CB-CD2 4.28Å; P164-F537 HydrophobicContact CB-CE1 3.49Å; P164-F537 VanDerWaalsContact CB-CE1 3.49Å; P164-F537 HydrophobicContact CB-CE2 3.74Å; P164-F537 HydrophobicContact CB-CG 4.44Å; P164-F537 HydrophobicContact CB-CZ 3.34Å; P164-F537 HydrophobicContact CG-CZ 4.4Å; P164-F537 CarbonylContact O-C 3.48Å; P164-F537 VanDerWaalsContact O-CA 3.22Å; P164-F537 WeakPolarHBondContact O-CA 3.29Å; F168-F537 AromaticContact CD2-CE2 3.67Å; F168-F537 HydrophobicContact CD2-CE2 3.67Å; F168-F537 HydrophobicContact CD2-CZ 4.06Å; F168-F537 AromaticContact CE2-CE2 3.89Å; F168-F537 HydrophobicContact CE2-CE2 3.89Å; F168-F537 HydrophobicContact CE2-CZ 4.23Å; M513-F537 PolarHBondContact O-N 3.09Å; E515-F537 HydrophobicContact CB-CD2 3.58Å; E515-F537 HydrophobicContact CB-CE2 3.69Å; E515-F537 HydrophobicContact CB-CG 4.06Å; E515-F537 HydrophobicContact CB-CZ 4.25Å; E515-F537 HydrophobicContact CG-CD2 4.05Å; E515-F537 HydrophobicContact CG-CE1 4.32Å; E515-F537 HydrophobicContact CG-CE2 3.64Å; E515-F537 HydrophobicContact CG-CZ 3.77Å; Q534-F537 HydrophobicContact CB-CD2 4.06Å; Q534-F537 HydrophobicContact CB-CE2 4.04Å; F537-W539 AromaticContact CD1-CD1 3.09Å; F537-W539 HydrophobicContact CD1-CD2 4.26Å; F537-W539 AromaticContact CD1-CE2 3.79Å; F537-W539 AromaticContact CD1-CG 3.84Å; F537-W539 HydrophobicContact CD1-CG 3.84Å; F537-W539 HydrophobicContact CD1-CZ2 4.49Å; F537-W539 AromaticContact CD1-NE1 3.16Å; F537-W539 AromaticContact CE1-CD1 3.44Å; F537-W539 VanDerWaalsContact CE1-CD1 3.44Å; F537-W539 AromaticContact CE1-CD2 3.81Å; F537-W539 HydrophobicContact CE1-CD2 3.81Å; F537-W539 AromaticContact CE1-CE2 3.34Å; F537-W539 AromaticContact CE1-CG 3.84Å; F537-W539 HydrophobicContact CE1-CG 3.84Å; F537-W539 AromaticContact CE1-CZ2 3.74Å; F537-W539 HydrophobicContact CE1-CZ2 3.74Å; F537-W539 AromaticContact CE1-NE1 3.23Å; F537-W539 HydrophobicContact CZ-CZ2 4.11Å; F537-W539 PolarHBondContact O-N 3.33Å; F537-T540 WeakPolarHBondContact O-CB 3.48Å; F537-T540 PolarHBondContact O-N 3.31Å; F537-N541 PolarHBondContact N-OD1 3.25Å; F537-N541 VanDerWaalsContact O-CG 3.27Å; F537-N541 PolarHBondContact O-N 3.4Å; F537-N541 PolarHBondContact O-OD1 3.38Å
538G93.8Very high90.7Very high0 Ų025.2 Ų25.20%014%0.144CC..Hα-helixtrans-47.4-52-165.700000115P164 V179 T540 G542P164-G538 PolarHBondContact O-N 3.11Å; V179-G538 VanDerWaalsContact CG2-C 3.46Å; G538-T540 VanDerWaalsContact C-N 3.3Å; G538-T540 PolarHBondContact O-N 3.47Å; G538-G542 PolarHBondContact O-N 2.93Å
539W96.9Very high91.2Very high5 Ų527.1 Ų27.12%0.01915%0.145CC..Hα-helixtrans-68.6-25.9179.4656.4000114.1W174 W178 W463 W469 P470 P471 E515 F537 G542 V543W174-W539 AromaticContact CE2-CZ3 3.87Å; W174-W539 HydrophobicContact CZ2-CH2 4.34Å; W174-W539 AromaticContact CZ2-CZ3 3.75Å; W174-W539 HydrophobicContact CZ2-CZ3 3.75Å; W174-W539 AromaticContact NE1-CZ3 3.92Å; W178-W539 HydrophobicContact CB-CB 3.97Å; W178-W539 HydrophobicContact CD2-CB 4.5Å; W178-W539 HydrophobicContact CE3-CB 4.22Å; W178-W539 HydrophobicContact CE3-CE3 4.4Å; W178-W539 HydrophobicContact CG-CB 4.42Å; W178-W539 HydrophobicContact CZ3-CE3 4.41Å; W463-W539 AromaticContact CH2-CH2 3.89Å; W463-W539 HydrophobicContact CH2-CH2 3.89Å; W463-W539 HydrophobicContact CH2-CZ3 4.22Å; W463-W539 AromaticContact CZ2-CH2 3.84Å; W463-W539 HydrophobicContact CZ2-CH2 3.84Å; W463-W539 HydrophobicContact CZ2-CZ3 4.45Å; W469-W539 HydrophobicContact CD2-CZ2 4.45Å; W469-W539 AromaticContact CE3-CH2 3.3Å; W469-W539 HydrophobicContact CE3-CH2 3.3Å; W469-W539 AromaticContact CE3-CZ2 3.12Å; W469-W539 HydrophobicContact CE3-CZ2 3.12Å; W469-W539 HydrophobicContact CE3-CZ3 4.45Å; W469-W539 AromaticContact CZ3-CH2 3.37Å; W469-W539 HydrophobicContact CZ3-CH2 3.37Å; W469-W539 AromaticContact CZ3-CZ2 3.21Å; W469-W539 HydrophobicContact CZ3-CZ2 3.21Å; P470-W539 HydrophobicContact CB-CG 4.41Å; P470-W539 HydrophobicContact CG-CG 4.39Å; P471-W539 HydrophobicContact CB-CE3 4.24Å; P471-W539 HydrophobicContact CG-CD2 4.16Å; P471-W539 HydrophobicContact CG-CE3 3.61Å; P471-W539 HydrophobicContact CG-CH2 4.34Å; P471-W539 HydrophobicContact CG-CZ3 3.7Å; E515-W539 HydrophobicContact CG-CZ2 3.79Å; E515-W539 PolarHBondContact O-NE1 3.19Å; F537-W539 AromaticContact CD1-CD1 3.09Å; F537-W539 HydrophobicContact CD1-CD2 4.26Å; F537-W539 AromaticContact CD1-CE2 3.79Å; F537-W539 AromaticContact CD1-CG 3.84Å; F537-W539 HydrophobicContact CD1-CG 3.84Å; F537-W539 HydrophobicContact CD1-CZ2 4.49Å; F537-W539 AromaticContact CD1-NE1 3.16Å; F537-W539 AromaticContact CE1-CD1 3.44Å; F537-W539 VanDerWaalsContact CE1-CD1 3.44Å; F537-W539 AromaticContact CE1-CD2 3.81Å; F537-W539 HydrophobicContact CE1-CD2 3.81Å; F537-W539 AromaticContact CE1-CE2 3.34Å; F537-W539 AromaticContact CE1-CG 3.84Å; F537-W539 HydrophobicContact CE1-CG 3.84Å; F537-W539 AromaticContact CE1-CZ2 3.74Å; F537-W539 HydrophobicContact CE1-CZ2 3.74Å; F537-W539 AromaticContact CE1-NE1 3.23Å; F537-W539 HydrophobicContact CZ-CZ2 4.11Å; F537-W539 PolarHBondContact O-N 3.33Å; W539-G542 PolarHBondContact O-N 3.39Å; W539-V543 VanDerWaalsContact O-CB 3.31Å; W539-V543 WeakPolarHBondContact O-CB 3.41Å; W539-V543 WeakPolarHBondContact O-CG2 3.4Å; W539-V543 PolarHBondContact O-N 3.35Å
540T97.8Very high91.8Very high0 Ų029.5 Ų29.50%015%0.148CC..Hα-helixtrans-77-42.5-175.1-52.60000106.8P470 M513 F514 Y517 F537 G538 V543 A544P470-T540 HydrophobicContact CG-CG2 3.97Å; P470-T540 WeakPolarHBondContact CG-OG1 3.46Å; M513-T540 HydrophobicContact CE-CG2 3.49Å; M513-T540 VanDerWaalsContact CE-CG2 3.49Å; F514-T540 WeakPolarHBondContact O-CB 3.14Å; F514-T540 PolarHBondContact O-OG1 3.47Å; Y517-T540 HydrophobicContact CE2-CG2 3.64Å; F537-T540 WeakPolarHBondContact O-CB 3.48Å; F537-T540 PolarHBondContact O-N 3.31Å; G538-T540 VanDerWaalsContact C-N 3.3Å; G538-T540 PolarHBondContact O-N 3.47Å; T540-V543 PolarHBondContact O-N 3.43Å; T540-A544 WeakPolarHBondContact O-CB 3.28Å; T540-A544 PolarHBondContact O-N 2.83Å
541N97.8Very high92.7Very high0 Ų028.5 Ų28.50%014%0.142CC..Hα-helixtrans-59-52.2171.4-57.5-3000109.1I130 W134 M513 G536 F537 V543 A544 L545I130-N541 HydrophobicContact CG2-CB 3.67Å; W134-N541 HydrophobicContact CH2-CB 3.58Å; W134-N541 HydrophobicContact CZ2-CB 4.04Å; W134-N541 HydrophobicContact CZ3-CB 4.07Å; M513-N541 VanDerWaalsContact CB-OD1 3.27Å; M513-N541 WeakPolarHBondContact CB-OD1 3.39Å; M513-N541 VanDerWaalsContact CG-OD1 3.29Å; M513-N541 WeakPolarHBondContact CG-OD1 3.17Å; G536-N541 PolarHBondContact O-ND2 3.12Å; G536-N541 PolarHBondContact O-OD1 3.37Å; F537-N541 PolarHBondContact N-OD1 3.25Å; F537-N541 VanDerWaalsContact O-CG 3.27Å; F537-N541 PolarHBondContact O-N 3.4Å; F537-N541 PolarHBondContact O-OD1 3.38Å; N541-V543 PolarHBondContact O-N 3.5Å; N541-A544 PolarHBondContact O-N 3.26Å; N541-L545 VanDerWaalsContact O-CG 3.3Å; N541-L545 WeakPolarHBondContact O-CG 3.32Å; N541-L545 PolarHBondContact O-N 3.15Å
542G98.3Very high93.5Very high0 Ų026.6 Ų26.60%014%0.135CC..Hα-helixtrans-58.6-44.3178.700000114.3W178 G538 W539 Q546W178-G542 VanDerWaalsContact O-CA 3.27Å; W178-G542 WeakPolarHBondContact O-CA 3.29Å; G538-G542 PolarHBondContact O-N 2.93Å; W539-G542 PolarHBondContact O-N 3.39Å; G542-Q546 VanDerWaalsContact O-CG 3.32Å; G542-Q546 WeakPolarHBondContact O-CG 3.38Å; G542-Q546 PolarHBondContact O-N 2.86Å; G542-Q546 VanDerWaalsContact O-N 3.09Å; G542-Q546 PolarHBondContact O-NE2 2.87Å
543V98.7Very high94.5Very high0 Ų022.4 Ų22.40%013%0.129CC..Hα-helixtrans-67.4-45.3177.4167.50000111.3W178 P470 H474 W539 T540 N541 L545 Q546 L547W178-V543 HydrophobicContact CB-CG2 4.19Å; W178-V543 HydrophobicContact CG-CG2 3.74Å; P470-V543 HydrophobicContact CB-CB 4.07Å; P470-V543 HydrophobicContact CB-CG1 4.34Å; P470-V543 HydrophobicContact CB-CG2 3.9Å; H474-V543 HydrophobicContact CB-CB 4.45Å; H474-V543 HydrophobicContact CB-CG1 3.91Å; H474-V543 HydrophobicContact CB-CG2 3.73Å; W539-V543 VanDerWaalsContact O-CB 3.31Å; W539-V543 WeakPolarHBondContact O-CB 3.41Å; W539-V543 WeakPolarHBondContact O-CG2 3.4Å; W539-V543 PolarHBondContact O-N 3.35Å; T540-V543 PolarHBondContact O-N 3.43Å; N541-V543 PolarHBondContact O-N 3.5Å; V543-L545 PolarHBondContact O-N 3.4Å; V543-Q546 PolarHBondContact O-N 2.98Å; V543-L547 HydrophobicContact CG1-CD1 3.94Å; V543-L547 HydrophobicContact CG1-CG 4.43Å; V543-L547 WeakPolarHBondContact O-CG 3.39Å; V543-L547 PolarHBondContact O-N 3.36Å
544A98.6Very high95.3Very high0 Ų024.4 Ų24.40%014%0.141CC..Hα-helixtrans-60.4-46178.700000111.1W126 I130 I500 M513 T540 N541 Q546 L547 L548W126-A544 HydrophobicContact CH2-CB 3.96Å; I130-A544 HydrophobicContact CD1-CB 4.07Å; I500-A544 HydrophobicContact CD1-CB 4.1Å; M513-A544 HydrophobicContact CE-CB 4.15Å; T540-A544 WeakPolarHBondContact O-CB 3.28Å; T540-A544 PolarHBondContact O-N 2.83Å; N541-A544 PolarHBondContact O-N 3.26Å; A544-Q546 PolarHBondContact O-N 3.15Å; A544-L547 PolarHBondContact O-N 3.44Å; A544-L548 VanDerWaalsContact O-CB 3.31Å; A544-L548 WeakPolarHBondContact O-CB 3.43Å; A544-L548 WeakPolarHBondContact O-CD1 3.47Å; A544-L548 VanDerWaalsContact O-CG 3.22Å; A544-L548 WeakPolarHBondContact O-CG 3.5Å; A544-L548 PolarHBondContact O-N 3.06Å
545L98.6Very high95.8Very high0 Ų023.3 Ų23.30%014%0.136CC..Hα-helixtrans-62.5-41.7177.3-65.5-171.1000112.2F114 A127 I130 W134 L185 N541 V543 L548 D549F114-L545 HydrophobicContact CE2-CD2 3.8Å; F114-L545 HydrophobicContact CZ-CD1 4.28Å; F114-L545 HydrophobicContact CZ-CD2 3.66Å; F114-L545 HydrophobicContact CZ-CG 4.43Å; A127-L545 HydrophobicContact CB-CD2 4.46Å; I130-L545 HydrophobicContact CB-CD2 4.08Å; I130-L545 HydrophobicContact CG2-CD1 4.3Å; I130-L545 HydrophobicContact CG2-CD2 3.82Å; I130-L545 HydrophobicContact CG2-CG 3.92Å; W134-L545 HydrophobicContact CZ2-CD1 3.9Å; L185-L545 HydrophobicContact CD1-CB 4.48Å; N541-L545 VanDerWaalsContact O-CG 3.3Å; N541-L545 WeakPolarHBondContact O-CG 3.32Å; N541-L545 PolarHBondContact O-N 3.15Å; V543-L545 PolarHBondContact O-N 3.4Å; L545-L548 PolarHBondContact O-N 3.49Å; L545-D549 WeakPolarHBondContact O-CB 3.33Å; L545-D549 PolarHBondContact O-N 3.33Å
546Q98.6Very high96.5Very high24 Ų2421.3 Ų21.311%0.11213%0.127CC..Hα-helixtrans-62.5-44.4176.7-77.5172.1104.400112.7N181 L185 H474 G542 V543 A544 D549 Q550N181-Q546 VanDerWaalsContact CB-CD 3.43Å; N181-Q546 HydrophobicContact CB-CG 4.08Å; N181-Q546 VanDerWaalsContact CB-OE1 3.22Å; L185-Q546 HydrophobicContact CD1-CB 4.3Å; L185-Q546 HydrophobicContact CD1-CG 3.72Å; H474-Q546 PolarHBondContact NE2-OE1 2.95Å; G542-Q546 VanDerWaalsContact O-CG 3.32Å; G542-Q546 WeakPolarHBondContact O-CG 3.38Å; G542-Q546 PolarHBondContact O-N 2.86Å; G542-Q546 VanDerWaalsContact O-N 3.09Å; G542-Q546 PolarHBondContact O-NE2 2.87Å; V543-Q546 PolarHBondContact O-N 2.98Å; A544-Q546 PolarHBondContact O-N 3.15Å; Q546-D549 PolarHBondContact O-N 2.95Å; Q546-Q550 VanDerWaalsContact O-CB 3.31Å; Q546-Q550 WeakPolarHBondContact O-CB 3.24Å; Q546-Q550 PolarHBondContact O-N 3.05Å
547L98.8Very high97.1Very high0 Ų020.9 Ų20.90%012%0.122CC..Hα-helixtrans-70.1-34.2178.3-67.8175.3000112.3I477 A496 W499 I500 V543 A544 Y551 L555I477-L547 HydrophobicContact CB-CD2 4.35Å; I477-L547 HydrophobicContact CD1-CD1 3.93Å; I477-L547 HydrophobicContact CD1-CD2 4.12Å; I477-L547 HydrophobicContact CG2-CD2 3.7Å; A496-L547 HydrophobicContact CB-CD2 4.18Å; W499-L547 HydrophobicContact CG-CD1 4.49Å; I500-L547 HydrophobicContact CD1-CB 3.93Å; I500-L547 HydrophobicContact CD1-CD1 4.36Å; I500-L547 HydrophobicContact CG1-CB 4.01Å; I500-L547 HydrophobicContact CG1-CD1 4.38Å; V543-L547 HydrophobicContact CG1-CD1 3.94Å; V543-L547 HydrophobicContact CG1-CG 4.43Å; V543-L547 WeakPolarHBondContact O-CG 3.39Å; V543-L547 PolarHBondContact O-N 3.36Å; A544-L547 PolarHBondContact O-N 3.44Å; L547-Y551 HydrophobicContact CD2-CD2 4.29Å; L547-Y551 HydrophobicContact CD2-CE2 4.16Å; L547-Y551 WeakPolarHBondContact O-CB 3.39Å; L547-Y551 PolarHBondContact O-N 2.86Å; L547-L555 WeakPolarHBondContact O-CD1 3.49Å
548L98.6Very high96.6Very high0 Ų023.1 Ų23.10%015%0.146CC..Hα-helixtrans-68.8-34.4173.4-75.8165.7000112.4I118 L123 W126 A127 I500 A544 L545 G552 L555I118-L548 HydrophobicContact CD1-CB 3.97Å; I118-L548 HydrophobicContact CD1-CD1 4.47Å; I118-L548 HydrophobicContact CD1-CD2 4.33Å; I118-L548 HydrophobicContact CG1-CB 4.33Å; I118-L548 HydrophobicContact CG2-CD2 4.47Å; L123-L548 HydrophobicContact CB-CD2 4.08Å; L123-L548 HydrophobicContact CD1-CD2 4.29Å; W126-L548 HydrophobicContact CE3-CD1 4.01Å; W126-L548 HydrophobicContact CZ3-CD1 3.79Å; W126-L548 HydrophobicContact CZ3-CG 4.46Å; A127-L548 HydrophobicContact CB-CD1 3.81Å; I500-L548 HydrophobicContact CD1-CG 4.04Å; I500-L548 HydrophobicContact CG2-CD2 4.14Å; A544-L548 VanDerWaalsContact O-CB 3.31Å; A544-L548 WeakPolarHBondContact O-CB 3.43Å; A544-L548 WeakPolarHBondContact O-CD1 3.47Å; A544-L548 VanDerWaalsContact O-CG 3.22Å; A544-L548 WeakPolarHBondContact O-CG 3.5Å; A544-L548 PolarHBondContact O-N 3.06Å; L545-L548 PolarHBondContact O-N 3.49Å; L548-G552 WeakPolarHBondContact O-CA 3.21Å; L548-G552 PolarHBondContact O-N 2.85Å; L548-L555 HydrophobicContact CD2-CD1 4.17Å
549D98.3Very high94.5Very high79 Ų7927.4 Ų27.442%0.42219%0.189SC..Hα-helixtrans-68.5-49.8171.5-179.269.6000110.7F114 L185 L545 Q546 Y551F114-D549 HydrophobicContact CB-CB 4.48Å; F114-D549 WeakPolarHBondContact CB-OD1 3.39Å; L185-D549 HydrophobicContact CD1-CB 3.98Å; L185-D549 HydrophobicContact CD2-CB 4.04Å; L545-D549 WeakPolarHBondContact O-CB 3.33Å; L545-D549 PolarHBondContact O-N 3.33Å; Q546-D549 PolarHBondContact O-N 2.95Å; D549-Y551 PolarHBondContact O-N 3.28Å
550Q98.1Very high91.6Very high82 Ų8229.8 Ų29.838%0.38322%0.216SC..Hα-helixtrans-64.6-40.2-176.5-174.6176.72.200113.5Q546Q546-Q550 VanDerWaalsContact O-CB 3.31Å; Q546-Q550 WeakPolarHBondContact O-CB 3.24Å; Q546-Q550 PolarHBondContact O-N 3.05Å
551Y98.4Very high88.7Confident28 Ų2841.4 Ų41.411%0.1126%0.26CS..Hα-helixtrans-121.610.1-172.9-59.6-71.9000113.6I477 S481 F493 A496 L547 D549 A553 T554 L555I477-Y551 HydrophobicContact CG2-CE2 3.92Å; S481-Y551 WeakPolarHBondContact CB-OH 3.33Å; F493-Y551 HydrophobicContact CB-CE1 4.26Å; F493-Y551 AromaticContact CD2-CD1 3.69Å; F493-Y551 HydrophobicContact CD2-CD1 3.69Å; F493-Y551 HydrophobicContact CD2-CE1 4.2Å; F493-Y551 HydrophobicContact CD2-CG 4.11Å; F493-Y551 HydrophobicContact CE2-CD1 4.48Å; A496-Y551 HydrophobicContact CB-CD2 3.61Å; A496-Y551 HydrophobicContact CB-CE2 3.73Å; A496-Y551 HydrophobicContact CB-CG 4.4Å; L547-Y551 HydrophobicContact CD2-CD2 4.29Å; L547-Y551 HydrophobicContact CD2-CE2 4.16Å; L547-Y551 WeakPolarHBondContact O-CB 3.39Å; L547-Y551 PolarHBondContact O-N 2.86Å; D549-Y551 PolarHBondContact O-N 3.28Å; Y551-A553 PolarHBondContact O-N 3.39Å; Y551-A553 VanDerWaalsContact O-N 3.07Å; Y551-T554 PolarHBondContact O-N 3.01Å; Y551-T554 PolarHBondContact O-OG1 3.05Å; Y551-L555 WeakPolarHBondContact O-CG 3.47Å; Y551-L555 PolarHBondContact O-N 3.15Å
552G97.4Very high85.8Confident1 Ų147.7 Ų47.71%0.0130%0.298CS..THydrogen-bonded Turntrans-56.4-30.6-173.100000114.9G117 I118 A119 L548 T554G117-G552 CarbonylContact O-C 3.53Å; G117-G552 VanDerWaalsContact O-C 3.23Å; I118-G552 CarbonylContact C-O 3.59Å; I118-G552 WeakPolarHBondContact CA-O 3.33Å; A119-G552 PolarHBondContact N-O 3.29Å; L548-G552 WeakPolarHBondContact O-CA 3.21Å; L548-G552 PolarHBondContact O-N 2.85Å; G552-T554 PolarHBondContact O-N 3.17Å
553A97.7Very high82.7Confident76 Ų7657.5 Ų57.563%0.62834%0.335SS*.THydrogen-bonded Turntrans-67.4-21.9178.100000113.5G117 Y551G117-A553 PolarHBondContact O-N 3.34Å; Y551-A553 PolarHBondContact O-N 3.39Å; Y551-A553 VanDerWaalsContact O-N 3.07Å
554T97.2Very high79.7Confident81 Ų8162.5 Ų62.550%0.49737%0.37SS..THydrogen-bonded Turntrans-124.2-21.6-172.453.50000114.3F493 Y551 G552F493-T554 WeakPolarHBondContact CE2-OG1 3.47Å; Y551-T554 PolarHBondContact O-N 3.01Å; Y551-T554 PolarHBondContact O-OG1 3.05Å; G552-T554 PolarHBondContact O-N 3.17Å
555L97.8Very high76.6Confident3 Ų367.7 Ų67.72%0.01640%0.398CS..  trans-61.5145.1174.4-74.7171.1000111.8L123 F493 Q497 I500 L547 L548 Y551L123-L555 HydrophobicContact CD1-CB 3.81Å; F493-L555 HydrophobicContact CE2-CD2 4.18Å; F493-L555 HydrophobicContact CE2-CG 4.45Å; Q497-L555 HydrophobicContact CB-CD2 3.95Å; I500-L555 HydrophobicContact CB-CD1 4.45Å; I500-L555 HydrophobicContact CG1-CD1 3.98Å; I500-L555 HydrophobicContact CG2-CD1 4.37Å; L547-L555 WeakPolarHBondContact O-CD1 3.49Å; L548-L555 HydrophobicContact CD2-CD1 4.17Å; Y551-L555 WeakPolarHBondContact O-CG 3.47Å; Y551-L555 PolarHBondContact O-N 3.15Å
556T95.8Very high73.7Confident52 Ų5275.7 Ų75.732%0.31944%0.439SS..  trans-131.9145.3178.473.20000112D120 Q497D120-T556 WeakPolarHBondContact OD2-CA 3.47Å; Q497-T556 PolarHBondContact NE2-O 3.04Å; Q497-T556 PolarHBondContact OE1-O 3.4Å; Q497-T556 PolarHBondContact OE1-OG1 3.27Å
557S91.3Very high70.8Confident7 Ų782.4 Ų82.45%0.04948%0.475CS..SBendtrans-76.2-24.7171.9570000112.2D120 W504D120-S557 PolarHBondContact OD1-OG 3.06Å; D120-S557 VanDerWaalsContact OD1-OG 3.1Å; D120-S557 PolarHBondContact OD2-N 2.99Å; D120-S557 PolarHBondContact OD2-OG 3.07Å; W504-S557 WeakPolarHBondContact CZ3-O 3.45Å
558G81.2Confident67.5Low48 Ų4889.8 Ų89.850%0.49551%0.514SS..SBendtrans150150.4167.700000114.9
559G49.7Very low64.6Low89 Ų8994.7 Ų94.792%0.91855%0.546SS*.  trans128.1-11.4167.400000117.1
560G36.3Very low61.4Low56 Ų5699.8 Ų99.858%0.57757%0.572SS**  trans-116.8113178.200000111.9V562G560-V562 PolarHBondContact O-N 3.26Å
561R35.4Very low58.4Low244 Ų244101.9 Ų101.992%0.92159%0.59SS**  trans-51.8125.4147.8-85.2178.8174175.4-2.1105.8R563R561-R563 VanDerWaalsContact C-N 3.32Å; R561-R563 PolarHBondContact O-N 3.32Å
562V37.4Very low55.2Low131 Ų131104.8 Ų104.879%0.79462%0.62SS**  trans-52.7107159.4177.20000105.3G560 S564G560-V562 PolarHBondContact O-N 3.26Å; V562-S564 PolarHBondContact O-N 3.23Å; V562-S564 VanDerWaalsContact O-N 3.1Å
563R32.7Very low52Low207 Ų207110.8 Ų110.878%0.78166%0.662SS**  trans-62.6115.4171.5-92.2-175.5173.3175.6-2.4105.7R561 D565R561-R563 VanDerWaalsContact C-N 3.32Å; R561-R563 PolarHBondContact O-N 3.32Å; R563-D565 PolarHBondContact O-N 3.43Å
564S36.3Very low49.2Very low105 Ų105114.1 Ų114.173%0.73467%0.674SS**SBendtrans-63.910.8169.245.30000113.9V562V562-S564 PolarHBondContact O-N 3.23Å; V562-S564 VanDerWaalsContact O-N 3.1Å
565D32.8Very low46.1Very low109 Ų109114.3 Ų114.358%0.58368%0.684SS**THydrogen-bonded Turntrans-102.715.4-164.3-59.5-18.5000114.2R563R563-D565 PolarHBondContact O-N 3.43Å
566L38.1Very low43Very low167 Ų167122.4 Ų122.487%0.87473%0.726SS**THydrogen-bonded Turntrans-99.117.4174.1-104.7148.3000114.3
567L38.1Very low39.9Very low165 Ų165129.2 Ų129.286%0.86476%0.756SS**  trans-131.575.4167.5-72.1169.5000110.2
568L30Very low37.2Very low155 Ų155136.9 Ų136.981%0.81280%0.796SS**  trans-104.1130.5158.9-93158.5000108.8
569P35.9Very low34.9Very low103 Ų103150 Ų15067%0.66983%0.831SS**  trans-76.5138.3-177.331.3-31.4000110.6V571P569-V571 HydrophobicContact CB-CG2 4.45Å; P569-V571 PolarHBondContact O-N 3.45Å
570L32.9Very low34.2Very low187 Ų187153 Ų15398%0.97983%0.826SS**  trans-66.291.3169.6-126.2123.2000109
571V35Very low34.1Very low126 Ų126158.1 Ų158.176%0.76484%0.839SS**  trans-139.7137.7169.6-1740000109.7P569P569-V571 HydrophobicContact CB-CG2 4.45Å; P569-V571 PolarHBondContact O-N 3.45Å
572A30.2Very low34Very low88 Ų88153.3 Ų153.373%0.72784%0.835SS**  trans89.389.917100000117.2
573S30.2Very low33.8Very low128 Ų128154.6 Ų154.690%0.89584%0.837SS**  trans-146.876.3142.5-71.80000109.5
574V38.3Very low33.9Very low145 Ų145151.4 Ų151.488%0.87984%0.841SS**  trans-133.4136.8157.6178.20000107.1
575A32.9Very low33.7Very low86 Ų86154.5 Ų154.571%0.71185%0.848SS**  trans95.694.917400000116.1
576L31.9Very low33.8Very low172 Ų172157.7 Ų157.790%0.90187%0.867SS**  172.584123.4-96.5139000110.1
577M30.3Very low33.5Very low195 Ų195157 Ų15796%0.96187%0.866SS**  trans-125.491151.1-84.1-162.3-178.300108.1
578L35.8Very low33.1Very low168 Ų168156.3 Ų156.388%0.8887%0.866SS**  trans-140.783.5154.2-92171.3000106.5
579R33.5Very low33.4Very low323 Ų323156.5 Ų156.5100%1.21987%0.871SS**  trans-172.30136.1-102.9178.9-171.7-153.92.2110.2

Retrieved 579 of 579 residues in 366 ms (Link to these results)