A0A087XY96_POEFO Loading...

DNA-binding protein SMUBP-2

5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. Specific to 5'-phosphorylated single-stranded guanine-rich sequences. May play a role in RNA metabolism, ribosome biogenesis or initiation of translation. May play a role in regulation of transcription. Interacts with tRNA-Tyr.

AlphaFold DB , UniProt , Accession A0A087XY96, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 993 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1A58.3Low87.6Confident86 Ų8672.9 Ų72.971%0.71139%0.394SS*.  0-76.5000000113.9A3 L4 E5 D173A1-A3 PolarHBondContact O-N 3.11Å; A1-A3 VanDerWaalsContact O-N 3.14Å; A1-L4 VanDerWaalsContact O-CB 3.27Å; A1-L4 WeakPolarHBondContact O-CB 3.04Å; A1-L4 PolarHBondContact O-N 3.39Å; A1-E5 PolarHBondContact O-N 2.85Å; A1-D173 PolarHBondContact N-OD2 2.81Å
2M67.2Low88.4Confident163 Ų16369.8 Ų69.880%0.80338%0.377SS*.Hα-helixtrans-58-30.5-178.3-78.7-157.6-70.200114.2L4 K6M2-L4 VanDerWaalsContact C-N 3.32Å; M2-L4 PolarHBondContact O-N 3.38Å; M2-K6 WeakPolarHBondContact O-CB 3.44Å; M2-K6 PolarHBondContact O-N 3.47Å; M2-K6 VanDerWaalsContact O-N 3.11Å
3A83.8Confident89Confident50 Ų5074.8 Ų74.841%0.41340%0.397SS..Hα-helixtrans-61.6-38.8174.300000112.8A1 F7A1-A3 PolarHBondContact O-N 3.11Å; A1-A3 VanDerWaalsContact O-N 3.14Å; A3-F7 WeakPolarHBondContact O-CB 3.44Å; A3-F7 PolarHBondContact O-N 2.66Å
4L91Very high89.4Confident21 Ų2170.1 Ų70.111%0.1137%0.371CS..Hα-helixtrans-65.6-49.8179.4-176.964.1000111.5A1 M2 K6 F7 V8 L155 I167 F171A1-L4 VanDerWaalsContact O-CB 3.27Å; A1-L4 WeakPolarHBondContact O-CB 3.04Å; A1-L4 PolarHBondContact O-N 3.39Å; M2-L4 VanDerWaalsContact C-N 3.32Å; M2-L4 PolarHBondContact O-N 3.38Å; L4-K6 PolarHBondContact O-N 2.72Å; L4-F7 WeakPolarHBondContact O-CB 3.25Å; L4-F7 PolarHBondContact O-N 3.24Å; L4-V8 WeakPolarHBondContact O-CG2 3.38Å; L4-V8 PolarHBondContact O-N 3.28Å; L4-L155 HydrophobicContact CD1-CD1 3.9Å; L4-L155 HydrophobicContact CD1-CD2 4.04Å; L4-L155 HydrophobicContact CD1-CG 3.78Å; L4-I167 HydrophobicContact CD1-CG2 4.43Å; L4-I167 HydrophobicContact CD2-CG2 4.41Å; L4-F171 HydrophobicContact CD1-CD1 4.45Å; L4-F171 HydrophobicContact CD1-CD2 3.71Å; L4-F171 HydrophobicContact CD1-CE1 4.07Å; L4-F171 HydrophobicContact CD1-CE2 3.22Å; L4-F171 HydrophobicContact CD1-CG 4.31Å; L4-F171 HydrophobicContact CD1-CZ 3.44Å; L4-F171 VanDerWaalsContact CD1-CZ 3.44Å
5E91.9Very high89.7Confident110 Ų11065.9 Ų65.951%0.51435%0.349SS..Hα-helixtrans-65.4-39.7-178.7-175.3171.1-153.300111.8A1 V8 S9 N156A1-E5 PolarHBondContact O-N 2.85Å; E5-V8 PolarHBondContact O-N 3.12Å; E5-S9 WeakPolarHBondContact O-CB 3.45Å; E5-S9 PolarHBondContact O-N 2.65Å; E5-S9 PolarHBondContact O-OG 3.39Å; E5-N156 WeakPolarHBondContact CA-OD1 3.33Å
6K93.7Very high89.9Confident165 Ų16565.9 Ų65.972%0.71735%0.347SS*.Hα-helixtrans-63.9-42.5172.3-173.7177.1-178.6179.40111.9M2 L4 K10M2-K6 WeakPolarHBondContact O-CB 3.44Å; M2-K6 PolarHBondContact O-N 3.47Å; M2-K6 VanDerWaalsContact O-N 3.11Å; L4-K6 PolarHBondContact O-N 2.72Å; K6-K10 VanDerWaalsContact O-CB 3.29Å; K6-K10 WeakPolarHBondContact O-CB 3.32Å; K6-K10 PolarHBondContact O-N 3.23Å
7F94.8Very high90.1Very high34 Ų3464.7 Ų64.715%0.14934%0.339CS..Hα-helixtrans-62-49.6175.2165.1-95.7000111.6A3 L4 S9 K10 T11 L152 L155 F171 E382 W386A3-F7 WeakPolarHBondContact O-CB 3.44Å; A3-F7 PolarHBondContact O-N 2.66Å; L4-F7 WeakPolarHBondContact O-CB 3.25Å; L4-F7 PolarHBondContact O-N 3.24Å; F7-S9 PolarHBondContact O-N 2.98Å; F7-K10 PolarHBondContact O-N 2.96Å; F7-T11 WeakPolarHBondContact CE2-OG1 3.41Å; F7-T11 VanDerWaalsContact O-CB 3.32Å; F7-T11 WeakPolarHBondContact O-CB 3.36Å; F7-T11 PolarHBondContact O-N 3.12Å; F7-T11 PolarHBondContact O-OG1 2.81Å; F7-L152 HydrophobicContact CE1-CD2 3.86Å; F7-L152 HydrophobicContact CZ-CD2 4.44Å; F7-L155 HydrophobicContact CD1-CD2 4.42Å; F7-L155 HydrophobicContact CE1-CD2 4.07Å; F7-F171 HydrophobicContact CB-CE1 3.76Å; F7-F171 HydrophobicContact CB-CZ 4.46Å; F7-F171 AromaticContact CD1-CE1 3.64Å; F7-F171 HydrophobicContact CD1-CE1 3.64Å; F7-F171 AromaticContact CD1-CZ 3.51Å; F7-F171 HydrophobicContact CD1-CZ 3.51Å; F7-F171 HydrophobicContact CD2-CE1 4.17Å; F7-F171 HydrophobicContact CE1-CE1 4.3Å; F7-F171 AromaticContact CE1-CZ 3.86Å; F7-F171 HydrophobicContact CE1-CZ 3.86Å; F7-F171 AromaticContact CG-CE1 3.57Å; F7-F171 HydrophobicContact CG-CE1 3.57Å; F7-F171 AromaticContact CG-CZ 3.96Å; F7-F171 HydrophobicContact CG-CZ 3.96Å; F7-E382 HydrophobicContact CE2-CG 4.29Å; F7-E382 WeakPolarHBondContact CE2-OE1 3.47Å; F7-E382 HydrophobicContact CZ-CG 3.86Å; F7-E382 VanDerWaalsContact CZ-OE1 3.29Å; F7-E382 WeakPolarHBondContact CZ-OE1 3.3Å; F7-W386 AromaticContact CE1-NE1 3.75Å; F7-W386 AromaticContact CZ-NE1 3.77Å
8V96.1Very high90.2Very high2 Ų261.6 Ų61.61%0.01232%0.322CS..Hα-helixtrans-61.2-48-179.6167.70000110.7L4 E5 K10 T11 L12 L152 L155 N156L4-V8 WeakPolarHBondContact O-CG2 3.38Å; L4-V8 PolarHBondContact O-N 3.28Å; E5-V8 PolarHBondContact O-N 3.12Å; V8-K10 PolarHBondContact O-N 3.39Å; V8-T11 PolarHBondContact O-N 3.3Å; V8-L12 HydrophobicContact CG1-CD1 3.65Å; V8-L12 HydrophobicContact CG1-CG 4.16Å; V8-L12 WeakPolarHBondContact O-CB 2.84Å; V8-L12 VanDerWaalsContact O-CG 3.25Å; V8-L12 WeakPolarHBondContact O-CG 3.33Å; V8-L12 PolarHBondContact O-N 2.68Å; V8-L152 HydrophobicContact CG1-CB 4.16Å; V8-L152 HydrophobicContact CG2-CD2 4.44Å; V8-L155 HydrophobicContact CG2-CD2 4.07Å; V8-L155 HydrophobicContact CG2-CG 4.33Å; V8-N156 HydrophobicContact CB-CB 4.31Å; V8-N156 HydrophobicContact CG1-CB 4.04Å; V8-N156 HydrophobicContact CG2-CB 4.09Å
9S95.9Very high90.2Very high53 Ų5361.6 Ų61.637%0.37132%0.317SS..Hα-helixtrans-58.9-50.8-179.7-55.40000111.2E5 F7 T11 L12 E13E5-S9 WeakPolarHBondContact O-CB 3.45Å; E5-S9 PolarHBondContact O-N 2.65Å; E5-S9 PolarHBondContact O-OG 3.39Å; F7-S9 PolarHBondContact O-N 2.98Å; S9-T11 PolarHBondContact O-N 2.78Å; S9-L12 PolarHBondContact O-N 3.09Å; S9-E13 PolarHBondContact O-N 3.14Å; S9-E13 VanDerWaalsContact O-N 3.15Å
10K96Very high90.1Very high104 Ų10463.9 Ų63.945%0.45233%0.327SS..Hα-helixtrans-58.3-48.7176.2-174.6-172.8176.7-166.40111.9K6 F7 V8 L12 E13 L14 K416K6-K10 VanDerWaalsContact O-CB 3.29Å; K6-K10 WeakPolarHBondContact O-CB 3.32Å; K6-K10 PolarHBondContact O-N 3.23Å; F7-K10 PolarHBondContact O-N 2.96Å; V8-K10 PolarHBondContact O-N 3.39Å; K10-L12 VanDerWaalsContact C-N 3.3Å; K10-L12 PolarHBondContact O-N 3.33Å; K10-E13 PolarHBondContact O-N 2.76Å; K10-L14 HydrophobicContact CG-CD1 4.18Å; K10-L14 WeakPolarHBondContact O-CG 3.4Å; K10-L14 PolarHBondContact O-N 3.29Å; K10-K416 WeakPolarHBondContact CE-O 3.24Å; K10-K416 PolarHBondContact NZ-O 3.42Å
11T95.4Very high90Very high14 Ų1462.3 Ų62.39%0.08632%0.323CS..Hα-helixtrans-67.6-31.5-176.9-58.40000112F7 V8 S9 L15 L152F7-T11 WeakPolarHBondContact CE2-OG1 3.41Å; F7-T11 VanDerWaalsContact O-CB 3.32Å; F7-T11 WeakPolarHBondContact O-CB 3.36Å; F7-T11 PolarHBondContact O-N 3.12Å; F7-T11 PolarHBondContact O-OG1 2.81Å; V8-T11 PolarHBondContact O-N 3.3Å; S9-T11 PolarHBondContact O-N 2.78Å; T11-L15 HydrophobicContact CG2-CD1 4.44Å; T11-L15 HydrophobicContact CG2-CG 4.47Å; T11-L15 WeakPolarHBondContact O-CB 3.36Å; T11-L15 VanDerWaalsContact O-CG 3.3Å; T11-L15 WeakPolarHBondContact O-CG 3.35Å; T11-L15 PolarHBondContact O-N 3Å; T11-L152 HydrophobicContact CG2-CD1 3.75Å; T11-L152 HydrophobicContact CG2-CD2 4.33Å
12L96.3Very high91.2Very high36 Ų3660.4 Ų60.419%0.18830%0.3CS..Hα-helixtrans-67-39.5173.5-75.6173.4000112.7V8 S9 K10 Q16 K149 L152V8-L12 HydrophobicContact CG1-CD1 3.65Å; V8-L12 HydrophobicContact CG1-CG 4.16Å; V8-L12 WeakPolarHBondContact O-CB 2.84Å; V8-L12 VanDerWaalsContact O-CG 3.25Å; V8-L12 WeakPolarHBondContact O-CG 3.33Å; V8-L12 PolarHBondContact O-N 2.68Å; S9-L12 PolarHBondContact O-N 3.09Å; K10-L12 VanDerWaalsContact C-N 3.3Å; K10-L12 PolarHBondContact O-N 3.33Å; L12-Q16 PolarHBondContact O-N 2.84Å; L12-Q16 VanDerWaalsContact O-N 3.12Å; L12-K149 HydrophobicContact CD2-CB 4.05Å; L12-K149 HydrophobicContact CD2-CD 4.19Å; L12-K149 HydrophobicContact CD2-CG 3.69Å; L12-L152 HydrophobicContact CD2-CB 4.11Å; L12-L152 HydrophobicContact CD2-CD1 3.83Å; L12-L152 HydrophobicContact CG-CB 4.38Å; L12-L152 HydrophobicContact CG-CD1 4.12Å
13E96.2Very high91.9Very high135 Ų13555.9 Ų55.963%0.63128%0.278SS*.Hα-helixtrans-63.1-47.9173.2-69.6170.1-173.200111.1S9 K10 L15 Q16 E17S9-E13 PolarHBondContact O-N 3.14Å; S9-E13 VanDerWaalsContact O-N 3.15Å; K10-E13 PolarHBondContact O-N 2.76Å; E13-L15 PolarHBondContact O-N 3.43Å; E13-Q16 WeakPolarHBondContact O-CB 3.3Å; E13-Q16 PolarHBondContact O-N 3.33Å; E13-Q16 VanDerWaalsContact O-N 3.08Å; E13-E17 PolarHBondContact O-N 3.5Å
14L95.8Very high91.9Very high8 Ų857.5 Ų57.54%0.04228%0.277CS..Hα-helixtrans-63.6-38.2179.3-63.5178.6000112.9K10 Q16 E17 E18 A413 K416 L418K10-L14 HydrophobicContact CG-CD1 4.18Å; K10-L14 WeakPolarHBondContact O-CG 3.4Å; K10-L14 PolarHBondContact O-N 3.29Å; L14-Q16 VanDerWaalsContact C-N 3.3Å; L14-Q16 PolarHBondContact O-N 3.04Å; L14-E17 PolarHBondContact O-N 3.11Å; L14-E18 WeakPolarHBondContact O-CB 3.4Å; L14-E18 PolarHBondContact O-N 3.4Å; L14-A413 HydrophobicContact CD2-CB 4.3Å; L14-K416 HydrophobicContact CD1-CB 4.29Å; L14-K416 HydrophobicContact CD2-CB 3.44Å; L14-K416 VanDerWaalsContact CD2-CB 3.44Å; L14-K416 HydrophobicContact CD2-CD 3.48Å; L14-K416 VanDerWaalsContact CD2-CD 3.48Å; L14-K416 HydrophobicContact CD2-CG 4.11Å; L14-L418 HydrophobicContact CB-CB 4.29Å; L14-L418 HydrophobicContact CB-CD1 4.18Å; L14-L418 HydrophobicContact CB-CD2 4.37Å; L14-L418 HydrophobicContact CD1-CB 4.23Å
15L93.8Very high91.2Very high8 Ų858.6 Ų58.64%0.04228%0.282CS..Hα-helixtrans-67.6-29.1173.6-78180000113.1T11 E13 R19 M148 L152 L418T11-L15 HydrophobicContact CG2-CD1 4.44Å; T11-L15 HydrophobicContact CG2-CG 4.47Å; T11-L15 WeakPolarHBondContact O-CB 3.36Å; T11-L15 VanDerWaalsContact O-CG 3.3Å; T11-L15 WeakPolarHBondContact O-CG 3.35Å; T11-L15 PolarHBondContact O-N 3Å; E13-L15 PolarHBondContact O-N 3.43Å; L15-R19 WeakPolarHBondContact O-CB 3.24Å; L15-R19 PolarHBondContact O-N 3.38Å; L15-R19 VanDerWaalsContact O-N 3.11Å; L15-M148 HydrophobicContact CD1-CB 3.9Å; L15-M148 HydrophobicContact CD1-CE 4.43Å; L15-M148 HydrophobicContact CD2-CE 3.64Å; L15-M148 HydrophobicContact CD2-SD 4.36Å; L15-L152 HydrophobicContact CD1-CD1 3.65Å; L15-L418 HydrophobicContact CD2-CD1 4.25Å
16Q93Very high90.4Very high65 Ų6554.9 Ų54.930%0.30427%0.266SS..Hα-helixtrans-73.8-43174.5-176.767.531.200110.6L12 E13 L14 R19 E20L12-Q16 PolarHBondContact O-N 2.84Å; L12-Q16 VanDerWaalsContact O-N 3.12Å; E13-Q16 WeakPolarHBondContact O-CB 3.3Å; E13-Q16 PolarHBondContact O-N 3.33Å; E13-Q16 VanDerWaalsContact O-N 3.08Å; L14-Q16 VanDerWaalsContact C-N 3.3Å; L14-Q16 PolarHBondContact O-N 3.04Å; Q16-R19 PolarHBondContact O-N 3.38Å; Q16-E20 WeakPolarHBondContact CG-OE1 3.35Å; Q16-E20 PolarHBondContact NE2-OE1 3.35Å; Q16-E20 WeakPolarHBondContact O-CB 3.18Å; Q16-E20 WeakPolarHBondContact O-CG 3.46Å; Q16-E20 PolarHBondContact O-N 2.97Å
17E93.4Very high89.6Confident46 Ų4650.4 Ų50.422%0.21525%0.247CC..Hα-helixtrans-61.5-42175.4-174.2175.4-167.200112E13 L14 E20 A21 T412 A413 K416E13-E17 PolarHBondContact O-N 3.5Å; L14-E17 PolarHBondContact O-N 3.11Å; E17-E20 PolarHBondContact O-N 2.88Å; E17-A21 PolarHBondContact O-N 3.27Å; E17-T412 VanDerWaalsContact OE1-CB 3.23Å; E17-T412 WeakPolarHBondContact OE1-CB 3.45Å; E17-T412 PolarHBondContact OE1-OG1 2.84Å; E17-A413 HydrophobicContact CB-CB 4.4Å; E17-A413 HydrophobicContact CG-CB 4.27Å; E17-K416 IonicContact OE1-NZ 3.16Å; E17-K416 PolarHBondContact OE1-NZ 3.45Å; E17-K416 IonicContact OE2-NZ 3.29Å; E17-K416 PolarHBondContact OE2-NZ 3.44Å
18E91.6Very high88.8Confident9 Ų952.6 Ų52.64%0.04226%0.26CS..Hα-helixtrans-64.7-44.3174175.862.2177.100112.4L14 E20 A21 E22 Y145 I408 K409 S410 L418L14-E18 WeakPolarHBondContact O-CB 3.4Å; L14-E18 PolarHBondContact O-N 3.4Å; E18-E20 VanDerWaalsContact C-N 3.33Å; E18-E20 PolarHBondContact O-N 2.89Å; E18-A21 PolarHBondContact O-N 2.95Å; E18-E22 PolarHBondContact O-N 3.42Å; E18-Y145 HydrophobicContact CB-CE1 4.5Å; E18-Y145 HydrophobicContact CG-CE1 4.12Å; E18-I408 WeakPolarHBondContact OE1-CA 3.24Å; E18-I408 VanDerWaalsContact OE2-CG2 3.25Å; E18-I408 WeakPolarHBondContact OE2-CG2 3.07Å; E18-K409 VanDerWaalsContact CD-N 3.35Å; E18-K409 PolarHBondContact OE1-N 3.05Å; E18-K409 PolarHBondContact OE2-N 3.28Å; E18-K409 VanDerWaalsContact OE2-N 3.11Å; E18-S410 VanDerWaalsContact OE2-CB 3.23Å; E18-S410 WeakPolarHBondContact OE2-CB 3.35Å; E18-S410 PolarHBondContact OE2-N 2.99Å; E18-L418 HydrophobicContact CB-CD2 3.8Å; E18-L418 HydrophobicContact CG-CD2 4.15Å
19R89Confident87.7Confident61 Ų6157 Ų5723%0.2328%0.276CS..Hα-helixtrans-61.6-40.2176.8180179.4177.3-87.6-3112.2L15 Q16 I23 D142 Y145L15-R19 WeakPolarHBondContact O-CB 3.24Å; L15-R19 PolarHBondContact O-N 3.38Å; L15-R19 VanDerWaalsContact O-N 3.11Å; Q16-R19 PolarHBondContact O-N 3.38Å; R19-I23 HydrophobicContact CG-CD1 3.97Å; R19-I23 WeakPolarHBondContact O-CB 3.44Å; R19-I23 WeakPolarHBondContact O-CD1 3.38Å; R19-I23 WeakPolarHBondContact O-CG1 3.27Å; R19-I23 PolarHBondContact O-N 2.95Å; R19-I23 VanDerWaalsContact O-N 3.08Å; R19-D142 IonicContact CZ-OD1 2.67Å; R19-D142 VanDerWaalsContact CZ-OD1 3.22Å; R19-D142 IonicContact NE-OD1 2.82Å; R19-D142 PolarHBondContact NE-OD1 3.46Å; R19-D142 IonicContact NH2-OD1 2.89Å; R19-D142 PolarHBondContact NH2-OD1 3.29Å; R19-D142 IonicContact NH2-OD2 3.55Å; R19-D142 PolarHBondContact NH2-OD2 3.42Å; R19-Y145 HydrophobicContact CB-CD1 3.74Å; R19-Y145 HydrophobicContact CB-CD2 4.4Å; R19-Y145 HydrophobicContact CB-CE1 3.69Å; R19-Y145 HydrophobicContact CB-CE2 4.36Å; R19-Y145 HydrophobicContact CB-CG 4.1Å; R19-Y145 HydrophobicContact CG-CD1 4.24Å; R19-Y145 HydrophobicContact CG-CD2 4.14Å; R19-Y145 HydrophobicContact CG-CE1 4.45Å; R19-Y145 HydrophobicContact CG-CE2 4.35Å; R19-Y145 HydrophobicContact CG-CG 4.08Å
20E89.3Confident86.5Confident108 Ų10857.8 Ų57.851%0.50527%0.274SS..Hα-helixtrans-67.4-39176.7-75.9170.6-169.300111.4Q16 E17 E18 I23 E24Q16-E20 WeakPolarHBondContact CG-OE1 3.35Å; Q16-E20 PolarHBondContact NE2-OE1 3.35Å; Q16-E20 WeakPolarHBondContact O-CB 3.18Å; Q16-E20 WeakPolarHBondContact O-CG 3.46Å; Q16-E20 PolarHBondContact O-N 2.97Å; E17-E20 PolarHBondContact O-N 2.88Å; E18-E20 VanDerWaalsContact C-N 3.33Å; E18-E20 PolarHBondContact O-N 2.89Å; E20-I23 PolarHBondContact O-N 3.49Å; E20-E24 WeakPolarHBondContact O-CB 3.33Å; E20-E24 PolarHBondContact O-N 2.9Å
21A87.6Confident85.6Confident31 Ų3159 Ų5926%0.25628%0.281SS..Hα-helixtrans-63.2-45173.400000113E17 E18 I23 E24 E25 K409E17-A21 PolarHBondContact O-N 3.27Å; E18-A21 PolarHBondContact O-N 2.95Å; A21-I23 VanDerWaalsContact C-N 3.34Å; A21-I23 PolarHBondContact O-N 3.4Å; A21-E24 PolarHBondContact O-N 2.88Å; A21-E25 WeakPolarHBondContact O-CB 3.24Å; A21-E25 PolarHBondContact O-N 3.04Å; A21-K409 HydrophobicContact CB-CB 4.39Å
22E83.5Confident84.7Confident45 Ų4564.3 Ų64.321%0.2131%0.309CS..Hα-helixtrans-62.7-39.5176-173.4-173.8153.400111.9E18 T26 A140 N141 Y145E18-E22 PolarHBondContact O-N 3.42Å; E22-T26 WeakPolarHBondContact O-CB 3.15Å; E22-T26 PolarHBondContact O-N 3.34Å; E22-T26 VanDerWaalsContact O-N 3.09Å; E22-T26 PolarHBondContact O-OG1 3.27Å; E22-A140 HydrophobicContact CG-CB 4.15Å; E22-A140 WeakPolarHBondContact OE1-CA 3.36Å; E22-A140 WeakPolarHBondContact OE1-CB 3.35Å; E22-N141 PolarHBondContact OE1-N 2.81Å; E22-Y145 WeakPolarHBondContact OE2-CE2 3.44Å; E22-Y145 VanDerWaalsContact OE2-CZ 3.3Å; E22-Y145 PolarHBondContact OE2-OH 2.76Å
23I82.3Confident83.8Confident69 Ų6964.3 Ų64.335%0.35431%0.309SS..Hα-helixtrans-66.5-45.8177.1-71.1167.2000110.9R19 E20 A21 T26 K27 A140R19-I23 HydrophobicContact CG-CD1 3.97Å; R19-I23 WeakPolarHBondContact O-CB 3.44Å; R19-I23 WeakPolarHBondContact O-CD1 3.38Å; R19-I23 WeakPolarHBondContact O-CG1 3.27Å; R19-I23 PolarHBondContact O-N 2.95Å; R19-I23 VanDerWaalsContact O-N 3.08Å; E20-I23 PolarHBondContact O-N 3.49Å; A21-I23 VanDerWaalsContact C-N 3.34Å; A21-I23 PolarHBondContact O-N 3.4Å; I23-T26 PolarHBondContact O-N 3.21Å; I23-K27 VanDerWaalsContact O-CB 3.31Å; I23-K27 WeakPolarHBondContact O-CB 3.42Å; I23-K27 PolarHBondContact O-N 3.38Å; I23-A140 HydrophobicContact CG1-CB 4.46Å
24E83.6Confident83Confident83 Ų8360.6 Ų60.639%0.38830%0.298SS..Hα-helixtrans-69.9-38.7-178.5-166.260.6-151.600111.7E20 A21 T26 K27 I28E20-E24 WeakPolarHBondContact O-CB 3.33Å; E20-E24 PolarHBondContact O-N 2.9Å; A21-E24 PolarHBondContact O-N 2.88Å; E24-T26 VanDerWaalsContact C-N 3.34Å; E24-T26 PolarHBondContact O-N 3.46Å; E24-K27 VanDerWaalsContact CD-NZ 3.3Å; E24-K27 PolarHBondContact O-N 3.43Å; E24-K27 IonicContact OE1-NZ 3.3Å; E24-K27 PolarHBondContact OE1-NZ 3.31Å; E24-K27 IonicContact OE2-NZ 3.53Å; E24-K27 PolarHBondContact OE2-NZ 2.93Å; E24-I28 HydrophobicContact CG-CD1 4.14Å; E24-I28 HydrophobicContact CG-CG1 4.48Å; E24-I28 WeakPolarHBondContact O-CB 3.39Å; E24-I28 VanDerWaalsContact O-CG1 3.24Å; E24-I28 WeakPolarHBondContact O-CG1 3.46Å; E24-I28 PolarHBondContact O-N 2.92Å
25E77.1Confident82.3Confident45 Ų4563.1 Ų63.121%0.2131%0.311CS..Hα-helixtrans-57.5-47171-175.3-173.5-172.600111.2A21 K27 I28 W29 K409A21-E25 WeakPolarHBondContact O-CB 3.24Å; A21-E25 PolarHBondContact O-N 3.04Å; E25-K27 VanDerWaalsContact C-N 3.32Å; E25-K27 PolarHBondContact O-N 2.94Å; E25-I28 PolarHBondContact O-N 3.45Å; E25-W29 HydrophobicContact CG-CZ2 4.26Å; E25-W29 VanDerWaalsContact O-CD1 3.28Å; E25-W29 PolarHBondContact O-N 2.89Å; E25-W29 VanDerWaalsContact O-N 3.14Å; E25-K409 IonicContact OE1-NZ 3.26Å; E25-K409 PolarHBondContact OE1-NZ 2.88Å; E25-K409 VanDerWaalsContact OE2-CD 3.31Å; E25-K409 WeakPolarHBondContact OE2-CD 3.27Å; E25-K409 WeakPolarHBondContact OE2-CE 3.23Å; E25-K409 IonicContact OE2-NZ 3.6Å; E25-K409 PolarHBondContact OE2-NZ 2.78Å
26T73.9Confident81.6Confident31 Ų3169.5 Ų69.519%0.1934%0.338CS..Hα-helixtrans-62.4-39177.1-56.60000111.7E22 I23 E24 W29 Q30E22-T26 WeakPolarHBondContact O-CB 3.15Å; E22-T26 PolarHBondContact O-N 3.34Å; E22-T26 VanDerWaalsContact O-N 3.09Å; E22-T26 PolarHBondContact O-OG1 3.27Å; I23-T26 PolarHBondContact O-N 3.21Å; E24-T26 VanDerWaalsContact C-N 3.34Å; E24-T26 PolarHBondContact O-N 3.46Å; T26-W29 PolarHBondContact O-N 2.88Å; T26-Q30 WeakPolarHBondContact O-CG 3.48Å; T26-Q30 PolarHBondContact O-N 3.13Å
27K77Confident80.9Confident72 Ų7270 Ų7031%0.31334%0.343SS..Hα-helixtrans-70.8-42.4179.4179.1171.7146.9-104.80112.2I23 E24 E25 W29 Q30 E31I23-K27 VanDerWaalsContact O-CB 3.31Å; I23-K27 WeakPolarHBondContact O-CB 3.42Å; I23-K27 PolarHBondContact O-N 3.38Å; E24-K27 VanDerWaalsContact CD-NZ 3.3Å; E24-K27 PolarHBondContact O-N 3.43Å; E24-K27 IonicContact OE1-NZ 3.3Å; E24-K27 PolarHBondContact OE1-NZ 3.31Å; E24-K27 IonicContact OE2-NZ 3.53Å; E24-K27 PolarHBondContact OE2-NZ 2.93Å; E25-K27 VanDerWaalsContact C-N 3.32Å; E25-K27 PolarHBondContact O-N 2.94Å; K27-W29 PolarHBondContact O-N 3.23Å; K27-Q30 PolarHBondContact O-N 3.24Å; K27-E31 WeakPolarHBondContact CE-OE1 3.4Å; K27-E31 HydrophobicContact CG-CG 4.3Å; K27-E31 PolarHBondContact O-N 3.09Å
28I77.9Confident80.2Confident80 Ų8068 Ų6841%0.4133%0.334SS..Hα-helixtrans-55.8-39.9172.2-71.8164.6000110.4E24 E25 N32E24-I28 HydrophobicContact CG-CD1 4.14Å; E24-I28 HydrophobicContact CG-CG1 4.48Å; E24-I28 WeakPolarHBondContact O-CB 3.39Å; E24-I28 VanDerWaalsContact O-CG1 3.24Å; E24-I28 WeakPolarHBondContact O-CG1 3.46Å; E24-I28 PolarHBondContact O-N 2.92Å; E25-I28 PolarHBondContact O-N 3.45Å; I28-N32 WeakPolarHBondContact O-CB 3.28Å; I28-N32 PolarHBondContact O-N 3.46Å; I28-N32 PolarHBondContact O-ND2 3.05Å; I28-N32 VanDerWaalsContact O-ND2 3.13Å
29W72.2Confident79.7Confident94 Ų9469.5 Ų69.536%0.35634%0.341SS..Hα-helixtrans-68.3-37.1174.6-67.19.3000112.7E25 T26 K27 I33 L38 V43E25-W29 HydrophobicContact CG-CZ2 4.26Å; E25-W29 VanDerWaalsContact O-CD1 3.28Å; E25-W29 PolarHBondContact O-N 2.89Å; E25-W29 VanDerWaalsContact O-N 3.14Å; T26-W29 PolarHBondContact O-N 2.88Å; K27-W29 PolarHBondContact O-N 3.23Å; W29-I33 HydrophobicContact CB-CD1 3.98Å; W29-I33 HydrophobicContact CG-CD1 3.97Å; W29-I33 VanDerWaalsContact O-CB 3.26Å; W29-I33 WeakPolarHBondContact O-CB 3.39Å; W29-I33 PolarHBondContact O-N 3.28Å; W29-L38 HydrophobicContact CB-CD2 4.19Å; W29-V43 HydrophobicContact CZ3-CG1 4.32Å
30Q71.1Confident78.9Confident69 Ų6971.6 Ų71.632%0.32236%0.357SS..Hα-helixtrans-70.3-35.4176.8-72.2175.412.200113.3T26 K27 L137T26-Q30 WeakPolarHBondContact O-CG 3.48Å; T26-Q30 PolarHBondContact O-N 3.13Å; K27-Q30 PolarHBondContact O-N 3.24Å; Q30-L137 HydrophobicContact CG-CD2 4.06Å
31E76.7Confident78.1Confident130 Ų13072 Ų7261%0.60736%0.357SS*.Hα-helixtrans-87.1-37.7-174.6-69.1179.2173.900113.1K27K27-E31 WeakPolarHBondContact CE-OE1 3.4Å; K27-E31 HydrophobicContact CG-CG 4.3Å; K27-E31 PolarHBondContact O-N 3.09Å
32N77.5Confident77.5Confident125 Ų12570.7 Ų70.767%0.66835%0.346SS*.Hα-helixtrans-102.1-9.8-171.9-61.1-66.9000115I28I28-N32 WeakPolarHBondContact O-CB 3.28Å; I28-N32 PolarHBondContact O-N 3.46Å; I28-N32 PolarHBondContact O-ND2 3.05Å; I28-N32 VanDerWaalsContact O-ND2 3.13Å
33I77.1Confident77.4Confident36 Ų3669.6 Ų69.619%0.18534%0.343CS..SBendtrans-114.8134-176-50.4179000109.5W29 D37 L38 K41W29-I33 HydrophobicContact CB-CD1 3.98Å; W29-I33 HydrophobicContact CG-CD1 3.97Å; W29-I33 VanDerWaalsContact O-CB 3.26Å; W29-I33 WeakPolarHBondContact O-CB 3.39Å; W29-I33 PolarHBondContact O-N 3.28Å; I33-D37 HydrophobicContact CG2-CB 3.56Å; I33-L38 HydrophobicContact CB-CD2 3.94Å; I33-L38 HydrophobicContact CB-CG 4.09Å; I33-L38 HydrophobicContact CD1-CD2 4.19Å; I33-L38 HydrophobicContact CG2-CD2 3.87Å; I33-L38 HydrophobicContact CG2-CG 3.89Å; I33-K41 HydrophobicContact CD1-CD 4.43Å
34S80.6Confident77.6Confident57 Ų5766.3 Ų66.340%0.39933%0.326SS..  trans-64.8148.4178.3910000111.1K36 D37 L38S34-K36 PolarHBondContact O-N 3.38Å; S34-K36 PolarHBondContact OG-N 3.24Å; S34-D37 WeakPolarHBondContact CB-OD2 3.34Å; S34-D37 PolarHBondContact O-N 2.96Å; S34-D37 VanDerWaalsContact OG-CG 3.23Å; S34-D37 PolarHBondContact OG-N 2.8Å; S34-D37 PolarHBondContact OG-OD2 3.3Å; S34-L38 PolarHBondContact O-N 3.28Å
35L80.4Confident77.8Confident61 Ų6162.4 Ų62.432%0.31931%0.307SS..Hα-helixtrans-54.6-30.7176.7-65.7179.9000112.8L38 Q39 L46 C96L35-L38 HydrophobicContact CD2-CD1 4.39Å; L35-Q39 PolarHBondContact O-N 3.05Å; L35-L46 HydrophobicContact CB-CD1 4.07Å; L35-L46 HydrophobicContact CB-CD2 4.17Å; L35-L46 HydrophobicContact CD1-CD2 4.45Å; L35-C96 HydrophobicContact CD2-CB 3.86Å
36K78.8Confident78.3Confident142 Ų14261.9 Ų61.962%0.61731%0.306SS*.Hα-helixtrans-72.2-37.4176.9-166.5177.2-177.1-175.90111.7S34 Q39 N40S34-K36 PolarHBondContact O-N 3.38Å; S34-K36 PolarHBondContact OG-N 3.24Å; K36-Q39 WeakPolarHBondContact O-CB 3.04Å; K36-Q39 PolarHBondContact O-N 3.35Å; K36-N40 PolarHBondContact O-N 3.45Å; K36-N40 PolarHBondContact O-ND2 3.22Å; K36-N40 PolarHBondContact O-OD1 3.46Å
37D77.5Confident78.9Confident77 Ų7766.3 Ų66.341%0.41232%0.323SS..Hα-helixtrans-75.4-31.6176.5-58.5-48000111.8I33 S34 Q39 N40 K41I33-D37 HydrophobicContact CG2-CB 3.56Å; S34-D37 WeakPolarHBondContact CB-OD2 3.34Å; S34-D37 PolarHBondContact O-N 2.96Å; S34-D37 VanDerWaalsContact OG-CG 3.23Å; S34-D37 PolarHBondContact OG-N 2.8Å; S34-D37 PolarHBondContact OG-OD2 3.3Å; D37-Q39 VanDerWaalsContact C-N 3.31Å; D37-N40 PolarHBondContact O-N 3.02Å; D37-N40 PolarHBondContact OD1-ND2 3.41Å; D37-K41 WeakPolarHBondContact O-CB 3.42Å; D37-K41 WeakPolarHBondContact O-CG 3.23Å; D37-K41 PolarHBondContact O-N 2.99Å
38L79.1Confident79.4Confident4 Ų463.1 Ų63.12%0.02131%0.309CS..Hα-helixtrans-64.3-34.8167.4-68.5177.2000112.3W29 I33 S34 L35 G42 V43 C44W29-L38 HydrophobicContact CB-CD2 4.19Å; I33-L38 HydrophobicContact CB-CD2 3.94Å; I33-L38 HydrophobicContact CB-CG 4.09Å; I33-L38 HydrophobicContact CD1-CD2 4.19Å; I33-L38 HydrophobicContact CG2-CD2 3.87Å; I33-L38 HydrophobicContact CG2-CG 3.89Å; S34-L38 PolarHBondContact O-N 3.28Å; L35-L38 HydrophobicContact CD2-CD1 4.39Å; L38-G42 PolarHBondContact O-N 3.46Å; L38-G42 VanDerWaalsContact O-N 3.14Å; L38-V43 HydrophobicContact CB-CG2 4.02Å; L38-V43 HydrophobicContact CD2-CG2 3.76Å; L38-V43 HydrophobicContact CG-CG2 4.48Å; L38-V43 WeakPolarHBondContact O-CG2 3.36Å; L38-V43 PolarHBondContact O-N 3.46Å; L38-C44 HydrophobicContact CB-CB 3.94Å; L38-C44 PolarHBondContact O-N 3Å
39Q81.1Confident79.9Confident40 Ų4061.5 Ų61.519%0.18730%0.299CS..Hα-helixtrans-69.8-40171.1-179.6168.560.900112L35 K36 D37 G42 C44 L46 P77L35-Q39 PolarHBondContact O-N 3.05Å; K36-Q39 WeakPolarHBondContact O-CB 3.04Å; K36-Q39 PolarHBondContact O-N 3.35Å; D37-Q39 VanDerWaalsContact C-N 3.31Å; Q39-G42 WeakPolarHBondContact O-CA 3.32Å; Q39-G42 PolarHBondContact O-N 3.35Å; Q39-C44 WeakPolarHBondContact CA-O 3.29Å; Q39-L46 HydrophobicContact CB-CD1 4.42Å; Q39-L46 VanDerWaalsContact NE2-N 3.16Å; Q39-P77 HydrophobicContact CG-CB 4.48Å; Q39-P77 HydrophobicContact CG-CG 4.04Å
40N73.5Confident80.6Confident105 Ų10558.1 Ų58.156%0.56129%0.288SS*.Hα-helixtrans-64.3-37.9173.6-64.6-27.3000112.2K36 D37 G42K36-N40 PolarHBondContact O-N 3.45Å; K36-N40 PolarHBondContact O-ND2 3.22Å; K36-N40 PolarHBondContact O-OD1 3.46Å; D37-N40 PolarHBondContact O-N 3.02Å; D37-N40 PolarHBondContact OD1-ND2 3.41Å; N40-G42 PolarHBondContact O-N 3.09Å
41K70.9Confident81.1Confident117 Ų11756.7 Ų56.751%0.50929%0.292SS..THydrogen-bonded Turntrans-71-7.4170.2-73.2-172.5175.7-164.70113.3I33 D37 V43I33-K41 HydrophobicContact CD1-CD 4.43Å; D37-K41 WeakPolarHBondContact O-CB 3.42Å; D37-K41 WeakPolarHBondContact O-CG 3.23Å; D37-K41 PolarHBondContact O-N 2.99Å; K41-V43 HydrophobicContact CB-CG2 4.45Å; K41-V43 PolarHBondContact O-N 3.4Å
42G75.7Confident81.4Confident3 Ų353.2 Ų53.23%0.03128%0.282CS..THydrogen-bonded Turntrans79.18.6174.900000116.3L38 Q39 N40 N79 S80 F81L38-G42 PolarHBondContact O-N 3.46Å; L38-G42 VanDerWaalsContact O-N 3.14Å; Q39-G42 WeakPolarHBondContact O-CA 3.32Å; Q39-G42 PolarHBondContact O-N 3.35Å; N40-G42 PolarHBondContact O-N 3.09Å; G42-N79 WeakPolarHBondContact O-CA 3.44Å; G42-N79 WeakPolarHBondContact O-CB 3.46Å; G42-S80 PolarHBondContact O-N 3.36Å; G42-S80 PolarHBondContact O-OG 2.69Å; G42-S80 VanDerWaalsContact O-OG 3.12Å; G42-F81 WeakPolarHBondContact O-CE2 3.44Å
43V82.1Confident81.7Confident22 Ų2250.6 Ų50.613%0.13327%0.266CS..SBendtrans-95.8-6.2-177.7-64.30000113.8W29 L38 K41 F81 K138W29-V43 HydrophobicContact CZ3-CG1 4.32Å; L38-V43 HydrophobicContact CB-CG2 4.02Å; L38-V43 HydrophobicContact CD2-CG2 3.76Å; L38-V43 HydrophobicContact CG-CG2 4.48Å; L38-V43 WeakPolarHBondContact O-CG2 3.36Å; L38-V43 PolarHBondContact O-N 3.46Å; K41-V43 HydrophobicContact CB-CG2 4.45Å; K41-V43 PolarHBondContact O-N 3.4Å; V43-F81 VanDerWaalsContact O-CZ 3.24Å; V43-F81 WeakPolarHBondContact O-CZ 3.42Å; V43-K138 WeakPolarHBondContact O-CB 3.49Å; V43-K138 PolarHBondContact O-N 3.22Å; V43-K138 VanDerWaalsContact O-N 3.1Å
44C86.8Confident81.8Confident0 Ų051 Ų510%027%0.272CS..EExtended strand (participates in β ladder)trans-135.8144.6177.9-171.30000111.6L38 Q39 L46 L136 L137L38-C44 HydrophobicContact CB-CB 3.94Å; L38-C44 PolarHBondContact O-N 3Å; Q39-C44 WeakPolarHBondContact CA-O 3.29Å; C44-L46 VanDerWaalsContact SG-CD2 3.54Å; C44-L136 CarbonylContact C-O 3.59Å; C44-L136 WeakPolarHBondContact CA-O 3.1Å; C44-L136 PolarHBondContact SG-O 2.88Å; C44-L137 HydrophobicContact CB-CD1 3.77Å
45L87.5Confident81.7Confident1 Ų148.9 Ų48.91%0.00526%0.257CS..EExtended strand (participates in β ladder)trans-123119.1171.5-62.8171.5000108.9L48 L76 P77 N79 F81 I115 L136L45-L48 HydrophobicContact CB-CD1 3.9Å; L45-L48 HydrophobicContact CB-CD2 4.42Å; L45-L48 HydrophobicContact CB-CG 4.32Å; L45-L48 HydrophobicContact CD1-CD1 4.38Å; L45-L76 HydrophobicContact CD1-CD1 4.46Å; L45-L76 HydrophobicContact CD1-CD2 4.21Å; L45-L76 HydrophobicContact CD2-CD2 4.48Å; L45-P77 HydrophobicContact CD2-CG 3.72Å; L45-N79 HydrophobicContact CD2-CB 4.11Å; L45-F81 HydrophobicContact CD1-CD2 4.25Å; L45-F81 HydrophobicContact CD1-CE2 4.04Å; L45-F81 HydrophobicContact CD1-CZ 4.47Å; L45-F81 HydrophobicContact CG-CD2 4.35Å; L45-F81 HydrophobicContact CG-CE2 3.74Å; L45-F81 HydrophobicContact CG-CZ 4.24Å; L45-I115 HydrophobicContact CD1-CD1 4.14Å; L45-I115 HydrophobicContact CD1-CG2 4.14Å; L45-L136 HydrophobicContact CB-CB 4.29Å; L45-L136 HydrophobicContact CD1-CD2 4.36Å; L45-L136 PolarHBondContact N-O 3.01Å; L45-L136 PolarHBondContact O-N 3.44Å
46L87.4Confident81.2Confident34 Ų3446.6 Ų46.618%0.17825%0.247CC..EExtended strand (participates in β ladder)trans-100147.5-174.8-57.5175.1000112.1L35 Q39 C44 L48 N135L35-L46 HydrophobicContact CB-CD1 4.07Å; L35-L46 HydrophobicContact CB-CD2 4.17Å; L35-L46 HydrophobicContact CD1-CD2 4.45Å; Q39-L46 HydrophobicContact CB-CD1 4.42Å; Q39-L46 VanDerWaalsContact NE2-N 3.16Å; C44-L46 VanDerWaalsContact SG-CD2 3.54Å; L46-L48 PolarHBondContact O-N 3.21Å; L46-N135 WeakPolarHBondContact CA-OD1 3.17Å; L46-N135 HydrophobicContact CD2-CB 4.14Å
47K85.5Confident80.6Confident124 Ų12441.7 Ų41.754%0.53923%0.228SC..EExtended strand (participates in β ladder)trans57.244.9169.5-54.2176.5-178.1178.60114.7Y134 N135K47-Y134 PolarHBondContact N-O 3.24Å; K47-N135 PolarHBondContact N-OD1 3.28Å
48L88Confident80Confident4 Ų441.3 Ų41.32%0.02122%0.221CC..EExtended strand (participates in β ladder)trans-78.3150.5170.6-55.6178.3000110.9L45 L46 L65 E66 L76 I115 L133 Y134 L136L45-L48 HydrophobicContact CB-CD1 3.9Å; L45-L48 HydrophobicContact CB-CD2 4.42Å; L45-L48 HydrophobicContact CB-CG 4.32Å; L45-L48 HydrophobicContact CD1-CD1 4.38Å; L46-L48 PolarHBondContact O-N 3.21Å; L48-L65 HydrophobicContact CB-CB 4.08Å; L48-L65 HydrophobicContact CB-CD2 4.44Å; L48-L65 HydrophobicContact CD1-CB 3.88Å; L48-L65 HydrophobicContact CD1-CD1 4.15Å; L48-E66 CarbonylContact C-O 3.57Å; L48-E66 WeakPolarHBondContact CA-O 3.41Å; L48-L76 HydrophobicContact CD2-CD2 3.61Å; L48-I115 HydrophobicContact CD1-CG2 3.9Å; L48-L133 CarbonylContact O-C 3.51Å; L48-L133 WeakPolarHBondContact O-CA 3.32Å; L48-Y134 PolarHBondContact N-O 3.17Å; L48-Y134 PolarHBondContact O-N 3.18Å; L48-L136 HydrophobicContact CD1-CB 4.06Å
49Q88.3Confident79.4Confident46 Ų4641.2 Ų41.222%0.21522%0.221CC..EExtended strand (participates in β ladder)trans-113.4154.5171.4-177.8172.96.500109.5G51 L65 E66 S130 D131Q49-G51 PolarHBondContact O-N 2.88Å; Q49-L65 CarbonylContact O-C 3.57Å; Q49-L65 VanDerWaalsContact O-CA 3.32Å; Q49-L65 WeakPolarHBondContact O-CA 3.31Å; Q49-E66 PolarHBondContact N-O 3.03Å; Q49-E66 PolarHBondContact O-N 3.21Å; Q49-S130 WeakPolarHBondContact CG-O 3.37Å; Q49-S130 PolarHBondContact NE2-O 3.2Å; Q49-D131 PolarHBondContact NE2-OD1 2.87Å
50I86.8Confident79.2Confident23 Ų2342.7 Ų42.712%0.11823%0.225CC..EExtended strand (participates in β ladder)trans-77.7116173.6-66174.8000110.1I63 L65 F128 Y134I50-I63 HydrophobicContact CB-CG2 4.39Å; I50-I63 HydrophobicContact CD1-CG2 3.92Å; I50-I63 HydrophobicContact CG1-CG2 3.76Å; I50-I63 HydrophobicContact CG2-CG2 3.88Å; I50-L65 HydrophobicContact CG1-CD2 3.67Å; I50-F128 HydrophobicContact CD1-CB 3.25Å; I50-F128 HydrophobicContact CD1-CD1 3.98Å; I50-F128 HydrophobicContact CD1-CG 3.71Å; I50-Y134 HydrophobicContact CD1-CD2 4.26Å; I50-Y134 HydrophobicContact CD1-CE2 3.76Å; I50-Y134 HydrophobicContact CG1-CD2 4.15Å; I50-Y134 HydrophobicContact CG1-CE2 4.04Å
51G82.7Confident79.4Confident39 Ų3938.1 Ų38.140%0.40220%0.2SC..EExtended strand (participates in β ladder)trans-82.8-41.9173.400000112.8Q49 V64Q49-G51 PolarHBondContact O-N 2.88Å; G51-V64 PolarHBondContact N-O 3.48Å
52S82.4Confident80Confident58 Ų5833.5 Ų33.541%0.40618%0.182SC..EExtended strand (participates in β ladder)trans-157163.3176.966.40000113.5V64S52-V64 PolarHBondContact N-O 3.45Å; S52-V64 PolarHBondContact O-N 3.38Å; S52-V64 WeakPolarHBondContact OG-CB 3.33Å; S52-V64 VanDerWaalsContact OG-CG2 3.27Å; S52-V64 WeakPolarHBondContact OG-CG2 3.42Å
53Q82.8Confident80.6Confident69 Ų6933.4 Ų33.432%0.32218%0.181SC..EExtended strand (participates in β ladder)trans-136.4129.8177.8-179.1-177.414.700108.3T61 V62 I63Q53-T61 HydrophobicContact CG-CG2 3.89Å; Q53-V62 WeakPolarHBondContact CA-O 3.31Å; Q53-I63 HydrophobicContact CG-CG1 4.47Å
54S80.1Confident80.9Confident46 Ų4633.4 Ų33.432%0.32218%0.181SC..EExtended strand (participates in β ladder)trans-145.5163.3-177.659.30000112.8V62S54-V62 PolarHBondContact N-O 2.95Å; S54-V62 PolarHBondContact O-N 3.31Å
55T77.5Confident81Confident12 Ų1233.5 Ų33.57%0.07418%0.181CC..EExtended strand (participates in β ladder)trans-86117.1176-54.40000111I300 D301 L330T55-I300 HydrophobicContact CG2-CD1 4.35Å; T55-I300 HydrophobicContact CG2-CG2 4.22Å; T55-I300 VanDerWaalsContact OG1-CG2 3.31Å; T55-I300 WeakPolarHBondContact OG1-CG2 3.35Å; T55-D301 WeakPolarHBondContact CB-OD1 3.37Å; T55-D301 PolarHBondContact N-OD1 3.01Å; T55-D301 PolarHBondContact OG1-OD1 3.48Å; T55-L330 HydrophobicContact CG2-CD2 4.34Å
56G70.6Confident81Confident12 Ų1235.7 Ų35.712%0.12419%0.191CC..  trans-96.4-174.1175.400000113.9G59 R60G56-G59 PolarHBondContact O-N 3.43Å; G56-R60 PolarHBondContact N-O 3.29Å
57L66.2Low80.9Confident39 Ų3934.9 Ų34.920%0.20419%0.189CC..G310 helixtrans-57.4148.3179.6-68.9146.2000112.5G59 R60 D281 L284L57-G59 PolarHBondContact O-N 3.05Å; L57-R60 WeakPolarHBondContact O-CB 3.5Å; L57-R60 WeakPolarHBondContact O-CG 3.27Å; L57-R60 PolarHBondContact O-N 3.06Å; L57-D281 HydrophobicContact CD1-CB 4.13Å; L57-D281 WeakPolarHBondContact CD1-OD1 3.47Å; L57-D281 WeakPolarHBondContact CD1-OD2 3.34Å; L57-L284 HydrophobicContact CD2-CD1 4.36Å
58Y65.9Low80.5Confident70 Ų7034.5 Ų34.528%0.27518%0.184SC..G310 helixtrans60.815.1-174.7-50.9-77.7000114R60 E334 I338Y58-R60 VanDerWaalsContact C-N 3.32Å; Y58-E334 VanDerWaalsContact CA-OE2 3.27Å; Y58-E334 WeakPolarHBondContact CA-OE2 3.25Å; Y58-E334 PolarHBondContact N-OE2 3.24Å; Y58-I338 HydrophobicContact CE1-CD1 3.65Å
59G66.1Low79.4Confident1 Ų141.5 Ų41.51%0.0121%0.214CC..G310 helixtrans76.413.1-174.900000114.6G56 L57G56-G59 PolarHBondContact O-N 3.43Å; L57-G59 PolarHBondContact O-N 3.05Å
60R76.1Confident77.8Confident72 Ų7248.1 Ų48.127%0.27225%0.245SC..  trans-63.6147.2177.5-71.9173.9166.6-179.2-9.8111.4G56 L57 Y58 F119 D120G56-R60 PolarHBondContact N-O 3.29Å; L57-R60 WeakPolarHBondContact O-CB 3.5Å; L57-R60 WeakPolarHBondContact O-CG 3.27Å; L57-R60 PolarHBondContact O-N 3.06Å; Y58-R60 VanDerWaalsContact C-N 3.32Å; R60-F119 WeakPolarHBondContact CB-O 3.03Å; R60-D120 IonicContact CZ-OD1 3.93Å; R60-D120 IonicContact CZ-OD2 3.9Å; R60-D120 IonicContact NE-OD1 3.51Å; R60-D120 PolarHBondContact NE-OD1 3.25Å; R60-D120 IonicContact NE-OD2 3.64Å; R60-D120 VanDerWaalsContact NH2-CG 3.29Å; R60-D120 IonicContact NH2-OD1 3.66Å; R60-D120 PolarHBondContact NH2-OD1 3.17Å; R60-D120 VanDerWaalsContact NH2-OD1 3.12Å; R60-D120 IonicContact NH2-OD2 2.65Å; R60-D120 PolarHBondContact NH2-OD2 3.44Å
61T78.6Confident76.3Confident8 Ų852 Ų525%0.04927%0.265CS..EExtended strand (participates in β ladder)trans-86.3124.3172.4-58.70000109.1Q53 I63 A118 F119Q53-T61 HydrophobicContact CG-CG2 3.89Å; T61-I63 HydrophobicContact CG2-CG1 4.25Å; T61-A118 CarbonylContact O-C 3.55Å; T61-A118 WeakPolarHBondContact O-CA 3.47Å; T61-F119 PolarHBondContact N-O 2.92Å; T61-F119 VanDerWaalsContact N-O 3.14Å; T61-F119 PolarHBondContact O-N 2.83Å
62V83.3Confident74.6Confident21 Ų2153.6 Ų53.613%0.12728%0.282CS..EExtended strand (participates in β ladder)trans-104.8130.2175.3-175.10000109Q53 S54 V117 A118Q53-V62 WeakPolarHBondContact CA-O 3.31Å; S54-V62 PolarHBondContact N-O 2.95Å; S54-V62 PolarHBondContact O-N 3.31Å; V62-V117 WeakPolarHBondContact CA-O 3.43Å; V62-A118 HydrophobicContact CG2-CB 4.17Å
63I87.3Confident73.2Confident1 Ų157.6 Ų57.61%0.00529%0.292CS..EExtended strand (participates in β ladder)trans-119.5128.6179.5-56.7-179000108.3I50 Q53 T61 L65 S116 V117 F119 F128I50-I63 HydrophobicContact CB-CG2 4.39Å; I50-I63 HydrophobicContact CD1-CG2 3.92Å; I50-I63 HydrophobicContact CG1-CG2 3.76Å; I50-I63 HydrophobicContact CG2-CG2 3.88Å; Q53-I63 HydrophobicContact CG-CG1 4.47Å; T61-I63 HydrophobicContact CG2-CG1 4.25Å; I63-L65 HydrophobicContact CG2-CD2 4.29Å; I63-L65 HydrophobicContact CG2-CG 4.4Å; I63-S116 CarbonylContact O-C 3.58Å; I63-S116 WeakPolarHBondContact O-CA 3.42Å; I63-V117 PolarHBondContact N-O 2.91Å; I63-V117 PolarHBondContact O-N 2.82Å; I63-F119 HydrophobicContact CB-CE2 4.1Å; I63-F119 HydrophobicContact CD1-CD2 3.93Å; I63-F119 HydrophobicContact CD1-CE2 3.77Å; I63-F119 HydrophobicContact CG1-CD2 4.09Å; I63-F119 HydrophobicContact CG1-CE2 3.97Å; I63-F128 HydrophobicContact CD1-CD2 3.48Å; I63-F128 VanDerWaalsContact CD1-CD2 3.48Å; I63-F128 HydrophobicContact CD1-CE1 4.32Å; I63-F128 HydrophobicContact CD1-CE2 3.19Å; I63-F128 HydrophobicContact CD1-CG 4.16Å; I63-F128 HydrophobicContact CD1-CZ 3.65Å
64V88.2Confident72.1Confident22 Ų2259.4 Ų59.413%0.13331%0.312CS..EExtended strand (participates in β ladder)trans-97.2121.8173.7-175.50000108.6G51 S52 E66G51-V64 PolarHBondContact N-O 3.48Å; S52-V64 PolarHBondContact N-O 3.45Å; S52-V64 PolarHBondContact O-N 3.38Å; S52-V64 WeakPolarHBondContact OG-CB 3.33Å; S52-V64 VanDerWaalsContact OG-CG2 3.27Å; S52-V64 WeakPolarHBondContact OG-CG2 3.42Å; V64-E66 HydrophobicContact CG1-CG 4.49Å
65L88.9Confident71.7Confident1 Ų160 Ų601%0.00532%0.316CS..EExtended strand (participates in β ladder)trans-106.5132.3178.9-65167.3000110L48 Q49 I50 I63 I90 S114 I115 V117 L136L48-L65 HydrophobicContact CB-CB 4.08Å; L48-L65 HydrophobicContact CB-CD2 4.44Å; L48-L65 HydrophobicContact CD1-CB 3.88Å; L48-L65 HydrophobicContact CD1-CD1 4.15Å; Q49-L65 CarbonylContact O-C 3.57Å; Q49-L65 VanDerWaalsContact O-CA 3.32Å; Q49-L65 WeakPolarHBondContact O-CA 3.31Å; I50-L65 HydrophobicContact CG1-CD2 3.67Å; I63-L65 HydrophobicContact CG2-CD2 4.29Å; I63-L65 HydrophobicContact CG2-CG 4.4Å; L65-I90 HydrophobicContact CD1-CD1 4.06Å; L65-S114 CarbonylContact O-C 3.58Å; L65-S114 VanDerWaalsContact O-CA 3.24Å; L65-S114 WeakPolarHBondContact O-CA 3.06Å; L65-S114 WeakPolarHBondContact O-CB 3.49Å; L65-I115 HydrophobicContact CB-CG2 3.88Å; L65-I115 HydrophobicContact CD1-CG2 4.48Å; L65-I115 PolarHBondContact N-O 3.21Å; L65-I115 PolarHBondContact O-N 2.91Å; L65-V117 HydrophobicContact CD1-CG2 4.33Å; L65-L136 HydrophobicContact CD1-CD1 4.14Å
66E89.1Confident71.7Confident47 Ų4760.1 Ų60.122%0.2232%0.316CS..EExtended strand (participates in β ladder)trans-125.6152.1-175.1-65.1-179.2-175.900111.1L48 Q49 V64 K69L48-E66 CarbonylContact C-O 3.57Å; L48-E66 WeakPolarHBondContact CA-O 3.41Å; Q49-E66 PolarHBondContact N-O 3.03Å; Q49-E66 PolarHBondContact O-N 3.21Å; V64-E66 HydrophobicContact CG1-CG 4.49Å; E66-K69 WeakPolarHBondContact OE2-CE 3.16Å; E66-K69 IonicContact OE2-NZ 3.73Å; E66-K69 PolarHBondContact OE2-NZ 2.74Å
67P85.1Confident71.9Confident18 Ų1862 Ų6212%0.11733%0.326CS..EExtended strand (participates in β ladder)trans-57.7146.6164.6-18.829.1000112K69 L76 A113P67-K69 PolarHBondContact O-N 2.86Å; P67-K69 VanDerWaalsContact O-N 3.13Å; P67-L76 HydrophobicContact CG-CD2 3.96Å; P67-L76 HydrophobicContact CG-CG 4.29Å; P67-A113 WeakPolarHBondContact CD-O 3.15Å
68R76.9Confident72.2Confident116 Ų11664.9 Ų64.944%0.43835%0.35SS..  trans-67.2112.5178.5-165.7-174.2-162.8-172.23.9111.6H70 L71 L133R68-H70 PolarHBondContact O-N 3.39Å; R68-L71 HydrophobicContact CB-CD1 4.3Å; R68-L71 PolarHBondContact O-N 2.7Å; R68-L133 HydrophobicContact CG-CD2 4.45Å
69K65.2Low72.8Confident151 Ų15164 Ų6466%0.65735%0.35SS*.G310 helixtrans-54.5-29-171.6-66.9171.3-178.5163.80115.3E66 P67 L71E66-K69 WeakPolarHBondContact OE2-CE 3.16Å; E66-K69 IonicContact OE2-NZ 3.73Å; E66-K69 PolarHBondContact OE2-NZ 2.74Å; P67-K69 PolarHBondContact O-N 2.86Å; P67-K69 VanDerWaalsContact O-N 3.13Å; K69-L71 PolarHBondContact O-N 3.12Å
70H54.8Low73.1Confident185 Ų18566.7 Ų66.786%0.85637%0.368SS*.G310 helixtrans-80.4-2.2178.7-78.3-69.7000115.9R68R68-H70 PolarHBondContact O-N 3.39Å
71L53.9Low73Confident104 Ų10463.8 Ų63.855%0.54536%0.358SS..G310 helixtrans-96.46.1178.9-86162.1000114.3R68 K69 F73R68-L71 HydrophobicContact CB-CD1 4.3Å; R68-L71 PolarHBondContact O-N 2.7Å; K69-L71 PolarHBondContact O-N 3.12Å; L71-F73 HydrophobicContact CB-CD2 4.08Å; L71-F73 VanDerWaalsContact O-CD2 3.25Å; L71-F73 WeakPolarHBondContact O-CD2 3.22Å; L71-F73 WeakPolarHBondContact O-CE2 3.33Å; L71-F73 PolarHBondContact O-N 3.45Å
72G47.9Very low72.2Confident73 Ų7364.3 Ų64.375%0.75337%0.365SS*.SBendtrans78-3.5177.700000115.5
73F53.1Low70.7Confident141 Ų14166.6 Ų66.662%0.61838%0.38SS*.  trans-91.1110.6174.3-60.3-79.3000110.4L71 S75L71-F73 HydrophobicContact CB-CD2 4.08Å; L71-F73 VanDerWaalsContact O-CD2 3.25Å; L71-F73 WeakPolarHBondContact O-CD2 3.22Å; L71-F73 WeakPolarHBondContact O-CE2 3.33Å; L71-F73 PolarHBondContact O-N 3.45Å; F73-S75 VanDerWaalsContact C-N 3.35Å
74S59.8Low69.2Low108 Ų10866.6 Ų66.676%0.75538%0.38SS*.  trans-86.1-6.9171.753.10000113.5
75S71.5Confident68.1Low58 Ų5866.2 Ų66.241%0.40638%0.381SS..SBendtrans-129.3150.3-17762.40000112.6F73 Q112F73-S75 VanDerWaalsContact C-N 3.35Å; S75-Q112 CarbonylContact C-O 3.45Å; S75-Q112 WeakPolarHBondContact CA-O 3.17Å; S75-Q112 VanDerWaalsContact CB-O 3.3Å; S75-Q112 WeakPolarHBondContact CB-O 2.91Å
76L77.4Confident67.6Low14 Ų1467.3 Ų67.37%0.07339%0.387CS..PPolyproline II helixtrans-62.6145165.5-69.5173.1000110L45 L48 P67 Q112 I115L45-L76 HydrophobicContact CD1-CD1 4.46Å; L45-L76 HydrophobicContact CD1-CD2 4.21Å; L45-L76 HydrophobicContact CD2-CD2 4.48Å; L48-L76 HydrophobicContact CD2-CD2 3.61Å; P67-L76 HydrophobicContact CG-CD2 3.96Å; P67-L76 HydrophobicContact CG-CG 4.29Å; L76-Q112 PolarHBondContact N-O 2.71Å; L76-I115 HydrophobicContact CD1-CB 4.13Å; L76-I115 HydrophobicContact CD1-CG2 4.39Å
77P74.7Confident67.1Low51 Ų5166.2 Ų66.233%0.33138%0.382SS..PPolyproline II helixtrans-64.3156.4170.626.3-32.1000111.3Q39 L45 N79Q39-P77 HydrophobicContact CG-CB 4.48Å; Q39-P77 HydrophobicContact CG-CG 4.04Å; L45-P77 HydrophobicContact CD2-CG 3.72Å; P77-N79 PolarHBondContact O-N 3.04Å; P77-N79 PolarHBondContact O-ND2 3.07Å
78S72.1Confident67.1Low101 Ų10165.3 Ų65.371%0.70638%0.376SS*.SBendtrans-53.1125.5177.851.60000111.1
79N78.1Confident67.6Low52 Ų5259.8 Ų59.828%0.27836%0.356SS..  trans-146.8161.7-169.271.479.6000113.7G42 L45 P77 F81G42-N79 WeakPolarHBondContact O-CA 3.44Å; G42-N79 WeakPolarHBondContact O-CB 3.46Å; L45-N79 HydrophobicContact CD2-CB 4.11Å; P77-N79 PolarHBondContact O-N 3.04Å; P77-N79 PolarHBondContact O-ND2 3.07Å; N79-F81 HydrophobicContact CB-CD2 3.88Å; N79-F81 HydrophobicContact CB-CE2 4.33Å; N79-F81 WeakPolarHBondContact OD1-CD2 3.49Å; N79-F81 PolarHBondContact OD1-N 2.95Å
80S72.3Confident68.6Low56 Ų5652.7 Ų52.739%0.39233%0.325SS..  trans-111.121.9-175.568.60000112.7G42 K138G42-S80 PolarHBondContact O-N 3.36Å; G42-S80 PolarHBondContact O-OG 2.69Å; G42-S80 VanDerWaalsContact O-OG 3.12Å; S80-K138 PolarHBondContact O-NZ 2.72Å
81F74.7Confident70.1Confident11 Ų1144.1 Ų44.15%0.04829%0.285CS..  trans-74.5131.5170.5-64.4-103.3000107.8G42 V43 L45 N79 D86 V88 V107 I110 I115 L136 K138G42-F81 WeakPolarHBondContact O-CE2 3.44Å; V43-F81 VanDerWaalsContact O-CZ 3.24Å; V43-F81 WeakPolarHBondContact O-CZ 3.42Å; L45-F81 HydrophobicContact CD1-CD2 4.25Å; L45-F81 HydrophobicContact CD1-CE2 4.04Å; L45-F81 HydrophobicContact CD1-CZ 4.47Å; L45-F81 HydrophobicContact CG-CD2 4.35Å; L45-F81 HydrophobicContact CG-CE2 3.74Å; L45-F81 HydrophobicContact CG-CZ 4.24Å; N79-F81 HydrophobicContact CB-CD2 3.88Å; N79-F81 HydrophobicContact CB-CE2 4.33Å; N79-F81 WeakPolarHBondContact OD1-CD2 3.49Å; N79-F81 PolarHBondContact OD1-N 2.95Å; F81-D86 WeakPolarHBondContact CA-OD2 3.34Å; F81-V88 HydrophobicContact CD1-CG1 3.67Å; F81-V88 HydrophobicContact CE1-CG1 3.55Å; F81-V107 HydrophobicContact CD1-CG2 4.48Å; F81-I110 VanDerWaalsContact C-CD1 3.49Å; F81-I110 HydrophobicContact CB-CD1 3.41Å; F81-I110 VanDerWaalsContact CB-CD1 3.41Å; F81-I110 WeakPolarHBondContact O-CD1 3.4Å; F81-I115 HydrophobicContact CB-CD1 4.29Å; F81-I115 HydrophobicContact CD1-CD1 4.31Å; F81-I115 HydrophobicContact CG-CD1 4.29Å; F81-L136 HydrophobicContact CE1-CD2 4.13Å; F81-L136 HydrophobicContact CE1-CG 4.36Å; F81-K138 HydrophobicContact CD1-CB 4.23Å; F81-K138 HydrophobicContact CE1-CB 3.77Å; F81-K138 HydrophobicContact CZ-CB 4.17Å
82G62.8Low71.4Confident20 Ų2042.2 Ų42.221%0.20628%0.275CS..  trans-70.8141.617600000110.5A84 D86 I110G82-A84 PolarHBondContact O-N 3.22Å; G82-D86 PolarHBondContact N-OD2 2.93Å; G82-I110 VanDerWaalsContact O-CD1 3.27Å; G82-I110 WeakPolarHBondContact O-CD1 3.48Å
83P50.3Low72.7Confident69 Ų6941.8 Ų41.845%0.44826%0.259SS..SBendtrans-62.4-11.5-172.925.2-35.3000114.6R109 A269P83-R109 VanDerWaalsContact O-CA 3.28Å; P83-R109 WeakPolarHBondContact O-CA 3.48Å; P83-A269 WeakPolarHBondContact CB-O 3.37Å; P83-A269 WeakPolarHBondContact O-CB 3.46Å
84A56.5Low73.3Confident0 Ų039.7 Ų39.70%026%0.262CS..SBendtrans-149.3172.5149.600000112.1G82 D86 V107 H267 A269 R270G82-A84 PolarHBondContact O-N 3.22Å; A84-D86 VanDerWaalsContact C-N 3.32Å; A84-D86 PolarHBondContact O-N 2.9Å; A84-V107 CarbonylContact C-O 3.57Å; A84-V107 VanDerWaalsContact CA-O 3.28Å; A84-V107 WeakPolarHBondContact CA-O 3.42Å; A84-H267 HydrophobicContact CB-CB 3.82Å; A84-A269 HydrophobicContact CB-CB 4.28Å; A84-R270 VanDerWaalsContact C-NE 3.33Å; A84-R270 HydrophobicContact CB-CG 3.9Å; A84-R270 PolarHBondContact O-NE 3.35Å; A84-R270 PolarHBondContact O-NH2 3.46Å
85G65.9Low73.7Confident14 Ų1435.3 Ų35.314%0.14423%0.234CC..  trans71.38.7161.200000117.3V107 R270G85-V107 PolarHBondContact N-O 3.34Å; G85-R270 PolarHBondContact O-NH2 3.47Å; G85-R270 VanDerWaalsContact O-NH2 3.11Å
86D76.9Confident73.1Confident25 Ų2533.3 Ų33.313%0.13422%0.219CC..  trans-71.1140.2162.2-79.3-5.3000109.3F81 G82 A84 V107 K138F81-D86 WeakPolarHBondContact CA-OD2 3.34Å; G82-D86 PolarHBondContact N-OD2 2.93Å; A84-D86 VanDerWaalsContact C-N 3.32Å; A84-D86 PolarHBondContact O-N 2.9Å; D86-V107 HydrophobicContact CB-CG2 4.21Å; D86-V107 PolarHBondContact O-N 3.16Å; D86-K138 IonicContact OD1-NZ 3.16Å; D86-K138 VanDerWaalsContact OD2-CE 3.23Å; D86-K138 WeakPolarHBondContact OD2-CE 3.48Å; D86-K138 IonicContact OD2-NZ 2.65Å; D86-K138 PolarHBondContact OD2-NZ 3.48Å
87I79.2Confident72.4Confident23 Ų2335.6 Ų35.612%0.11824%0.237CC..EExtended strand (participates in β ladder)trans-81.2131.7170-56.5-169.4000107.9L139 N141 V143I87-L139 HydrophobicContact CG2-CB 4.21Å; I87-L139 HydrophobicContact CG2-CD1 4.42Å; I87-L139 PolarHBondContact O-N 3.23Å; I87-N141 VanDerWaalsContact CD1-OD1 3.31Å; I87-N141 WeakPolarHBondContact CD1-OD1 3.46Å; I87-V143 HydrophobicContact CD1-CB 4.19Å; I87-V143 HydrophobicContact CD1-CG2 3.67Å
88V85.1Confident71.8Confident0 Ų037.4 Ų37.40%026%0.256CS..EExtended strand (participates in β ladder)trans-131.1139.2-178.8-67.70000110.5F81 T104 G105 V107 V117 L136 L137F81-V88 HydrophobicContact CD1-CG1 3.67Å; F81-V88 HydrophobicContact CE1-CG1 3.55Å; V88-T104 WeakPolarHBondContact O-CA 3.14Å; V88-G105 PolarHBondContact N-O 3.39Å; V88-G105 PolarHBondContact O-N 3.39Å; V88-V107 HydrophobicContact CB-CG2 4.37Å; V88-V107 HydrophobicContact CG1-CG2 3.52Å; V88-V107 HydrophobicContact CG2-CG2 3.87Å; V88-V117 HydrophobicContact CG2-CB 4.46Å; V88-V117 HydrophobicContact CG2-CG1 3.54Å; V88-V117 HydrophobicContact CG2-CG2 3.99Å; V88-L136 HydrophobicContact CB-CD1 3.83Å; V88-L136 HydrophobicContact CB-CD2 4.42Å; V88-L136 HydrophobicContact CB-CG 4.01Å; V88-L136 HydrophobicContact CG1-CD2 4.36Å; V88-L136 HydrophobicContact CG1-CG 4.32Å; V88-L136 HydrophobicContact CG2-CD1 3.81Å; V88-L136 HydrophobicContact CG2-CG 4.37Å; V88-L137 CarbonylContact C-O 3.59Å; V88-L137 VanDerWaalsContact CA-O 3.27Å; V88-L137 WeakPolarHBondContact CA-O 3.35Å
89G86.6Confident71.1Confident0 Ų037.3 Ų37.30%026%0.262CS..EExtended strand (participates in β ladder)trans-92.4134.4166.900000109.4Y91 C103 L136 L137G89-Y91 VanDerWaalsContact C-CE2 3.47Å; G89-Y91 VanDerWaalsContact O-CD2 3.31Å; G89-Y91 WeakPolarHBondContact O-CD2 3.44Å; G89-Y91 WeakPolarHBondContact O-CE2 3.23Å; G89-C103 WeakPolarHBondContact CA-O 3.37Å; G89-L136 WeakPolarHBondContact O-CA 3.48Å; G89-L137 PolarHBondContact N-O 2.87Å; G89-L137 PolarHBondContact O-N 2.93Å
90I86.8Confident70.8Confident1 Ų135.8 Ų35.81%0.00526%0.255CS..EExtended strand (participates in β ladder)trans-91.2132.7162.4-67.3-174.3000108L65 I102 C103 F119 F128 Y134 N135 L136L65-I90 HydrophobicContact CD1-CD1 4.06Å; I90-I102 HydrophobicContact CG2-CB 4.43Å; I90-I102 HydrophobicContact CG2-CD1 4.24Å; I90-I102 PolarHBondContact O-N 3.19Å; I90-C103 PolarHBondContact N-O 3.01Å; I90-F119 HydrophobicContact CD1-CE1 4.18Å; I90-F119 HydrophobicContact CD1-CE2 4.26Å; I90-F119 HydrophobicContact CD1-CZ 3.45Å; I90-F119 VanDerWaalsContact CD1-CZ 3.45Å; I90-F119 HydrophobicContact CG1-CZ 4.16Å; I90-F128 HydrophobicContact CD1-CE1 4.04Å; I90-F128 HydrophobicContact CD1-CZ 4.44Å; I90-F128 HydrophobicContact CG2-CE1 4.27Å; I90-Y134 HydrophobicContact CG2-CD1 3.79Å; I90-Y134 HydrophobicContact CG2-CG 4.11Å; I90-N135 WeakPolarHBondContact CA-O 3.45Å; I90-L136 HydrophobicContact CD1-CD1 4.47Å; I90-L136 HydrophobicContact CG1-CD1 3.6Å
91Y85.8Confident71.1Confident5 Ų536.2 Ų36.22%0.0225%0.251CS..EExtended strand (participates in β ladder)trans-127.3154.6-179.9-58.8-100.5000110.8G89 G95 C96 S97 S100 Q101 N135 L137G89-Y91 VanDerWaalsContact C-CE2 3.47Å; G89-Y91 VanDerWaalsContact O-CD2 3.31Å; G89-Y91 WeakPolarHBondContact O-CD2 3.44Å; G89-Y91 WeakPolarHBondContact O-CE2 3.23Å; Y91-G95 WeakPolarHBondContact CB-O 3.15Å; Y91-C96 HydrophobicContact CD1-CB 4.23Å; Y91-C96 HydrophobicContact CD2-CB 4.36Å; Y91-C96 HydrophobicContact CG-CB 4.13Å; Y91-S97 WeakPolarHBondContact CD1-O 3.22Å; Y91-S97 VanDerWaalsContact CE1-O 3.24Å; Y91-S97 WeakPolarHBondContact CE1-O 3.3Å; Y91-S100 WeakPolarHBondContact CA-O 3.42Å; Y91-Q101 HydrophobicContact CD1-CB 3.84Å; Y91-Q101 HydrophobicContact CD1-CG 4.26Å; Y91-Q101 HydrophobicContact CE1-CB 3.48Å; Y91-Q101 VanDerWaalsContact CE1-CB 3.48Å; Y91-Q101 HydrophobicContact CE1-CG 3.75Å; Y91-Q101 HydrophobicContact CE2-CG 4.48Å; Y91-Q101 PolarHBondContact OH-OE1 3.1Å; Y91-N135 PolarHBondContact N-O 3.14Å; Y91-N135 PolarHBondContact O-N 2.79Å; Y91-L137 HydrophobicContact CD2-CB 4.13Å; Y91-L137 HydrophobicContact CE2-CB 3.68Å; Y91-L137 HydrophobicContact CE2-CD2 4.29Å
92D81.9Confident71.3Confident65 Ų6538.7 Ų38.735%0.34826%0.264SS..  trans-68.2149.9170.8-176.777000111.8S94 G95 S100 I102 N135D92-S94 PolarHBondContact O-N 3.44Å; D92-S94 WeakPolarHBondContact OD2-CB 3.26Å; D92-S94 PolarHBondContact OD2-N 3.34Å; D92-S94 PolarHBondContact OD2-OG 3.24Å; D92-G95 PolarHBondContact O-N 2.96Å; D92-S100 PolarHBondContact N-O 3.12Å; D92-I102 HydrophobicContact CB-CD1 4.39Å; D92-N135 PolarHBondContact O-ND2 2.8Å
93P74.3Confident72.2Confident63 Ų6338.8 Ų38.841%0.40926%0.261SS..THydrogen-bonded Turntrans-52.5-22.2175.914.4-33.1000115.5G95 L133 N135P93-G95 VanDerWaalsContact C-N 3.26Å; P93-G95 PolarHBondContact O-N 3.16Å; P93-L133 HydrophobicContact CB-CB 4.4Å; P93-L133 WeakPolarHBondContact CD-O 3.46Å; P93-L133 HydrophobicContact CG-CB 4.23Å; P93-N135 WeakPolarHBondContact CA-ND2 3.3Å
94S66.9Low73.7Confident98 Ų9839.5 Ų39.569%0.68526%0.264SS*.THydrogen-bonded Turntrans-63.6-22.3177.1550000114.8D92D92-S94 PolarHBondContact O-N 3.44Å; D92-S94 WeakPolarHBondContact OD2-CB 3.26Å; D92-S94 PolarHBondContact OD2-N 3.34Å; D92-S94 PolarHBondContact OD2-OG 3.24Å
95G67.1Low74.8Confident15 Ų1539.7 Ų39.716%0.15527%0.266CS..  trans165.3173.6174.300000113.4Y91 D92 P93 S100Y91-G95 WeakPolarHBondContact CB-O 3.15Å; D92-G95 PolarHBondContact O-N 2.96Å; P93-G95 VanDerWaalsContact C-N 3.26Å; P93-G95 PolarHBondContact O-N 3.16Å; G95-S100 VanDerWaalsContact C-OG 3.25Å; G95-S100 PolarHBondContact O-OG 2.86Å
96C59.6Low75.5Confident16 Ų1641.6 Ų41.611%0.10827%0.273CS..  trans-112.448.3176.9-56.70000112.3L35 Y91 N135 L137L35-C96 HydrophobicContact CD2-CB 3.86Å; Y91-C96 HydrophobicContact CD1-CB 4.23Å; Y91-C96 HydrophobicContact CD2-CB 4.36Å; Y91-C96 HydrophobicContact CG-CB 4.13Å; C96-N135 VanDerWaalsContact SG-CB 3.58Å; C96-L137 HydrophobicContact CB-CD2 4.18Å
97S63.6Low75.7Confident63 Ų6340.4 Ų40.444%0.44127%0.266SS..SBendtrans-96161.5176.874.50000110.9Y91 A99 S100 Q101Y91-S97 WeakPolarHBondContact CD1-O 3.22Å; Y91-S97 VanDerWaalsContact CE1-O 3.24Å; Y91-S97 WeakPolarHBondContact CE1-O 3.3Å; S97-A99 PolarHBondContact O-N 3.38Å; S97-S100 PolarHBondContact N-OG 2.95Å; S97-S100 VanDerWaalsContact N-OG 3.08Å; S97-S100 PolarHBondContact O-N 3.36Å; S97-S100 PolarHBondContact O-OG 3.04Å; S97-Q101 PolarHBondContact O-N 3.37Å
98A61.2Low75.4Confident88 Ų8840 Ų4073%0.72727%0.265SS*.THydrogen-bonded Turntrans-56.1-24.6177.200000113.6
99A58.2Low74.8Confident100 Ų10047.7 Ų47.783%0.82629%0.294SS*.THydrogen-bonded Turntrans-82-21.617700000114.1S97S97-A99 PolarHBondContact O-N 3.38Å
100S70.9Confident74.3Confident20 Ų2049.5 Ų49.514%0.1430%0.303CS..SBendtrans-98.48.3174.763.40000113.1Y91 D92 G95 S97 I102Y91-S100 WeakPolarHBondContact CA-O 3.42Å; D92-S100 PolarHBondContact N-O 3.12Å; G95-S100 VanDerWaalsContact C-OG 3.25Å; G95-S100 PolarHBondContact O-OG 2.86Å; S97-S100 PolarHBondContact N-OG 2.95Å; S97-S100 VanDerWaalsContact N-OG 3.08Å; S97-S100 PolarHBondContact O-N 3.36Å; S97-S100 PolarHBondContact O-OG 3.04Å; S100-I102 PolarHBondContact O-N 3.41Å
101Q79.2Confident73.8Confident65 Ų6551.5 Ų51.530%0.30432%0.317SS..EExtended strand (participates in β ladder)trans-76114.9178.5-167.71691.100110.9Y91 S97Y91-Q101 HydrophobicContact CD1-CB 3.84Å; Y91-Q101 HydrophobicContact CD1-CG 4.26Å; Y91-Q101 HydrophobicContact CE1-CB 3.48Å; Y91-Q101 VanDerWaalsContact CE1-CB 3.48Å; Y91-Q101 HydrophobicContact CE1-CG 3.75Å; Y91-Q101 HydrophobicContact CE2-CG 4.48Å; Y91-Q101 PolarHBondContact OH-OE1 3.1Å; S97-Q101 PolarHBondContact O-N 3.37Å
102I79.6Confident73.3Confident63 Ų6359.4 Ų59.432%0.32335%0.354SS..EExtended strand (participates in β ladder)trans-78.8-47.1-179.2-57.3179.7000110.1I90 D92 S100 A126 F128 Y134I90-I102 HydrophobicContact CG2-CB 4.43Å; I90-I102 HydrophobicContact CG2-CD1 4.24Å; I90-I102 PolarHBondContact O-N 3.19Å; D92-I102 HydrophobicContact CB-CD1 4.39Å; S100-I102 PolarHBondContact O-N 3.41Å; I102-A126 HydrophobicContact CG2-CB 4.43Å; I102-F128 HydrophobicContact CG2-CE1 4.29Å; I102-Y134 HydrophobicContact CD1-CD1 3.74Å; I102-Y134 HydrophobicContact CD1-CE1 3.57Å
103C80.9Confident73.3Confident22 Ų2258.5 Ų58.515%0.14936%0.356CS..EExtended strand (participates in β ladder)trans-163.2168.7-179.4570000111.9G89 I90 F119G89-C103 WeakPolarHBondContact CA-O 3.37Å; I90-C103 PolarHBondContact N-O 3.01Å; C103-F119 HydrophobicContact CB-CD1 4.36Å; C103-F119 HydrophobicContact CB-CE1 4.33Å; C103-F119 WeakPolarHBondContact SG-CE1 3.45Å
104T81.8Confident73.9Confident84 Ų8456.6 Ų56.652%0.51534%0.344SS..EExtended strand (participates in β ladder)trans-107.5140.8166.247.40000110.3V88 F119 L139V88-T104 WeakPolarHBondContact O-CA 3.14Å; T104-F119 VanDerWaalsContact O-CD1 3.25Å; T104-F119 WeakPolarHBondContact O-CD1 3.44Å; T104-L139 HydrophobicContact CG2-CD1 3.92Å
105G80Confident74.8Confident4 Ų452 Ų524%0.04131%0.311CS..EExtended strand (participates in β ladder)trans-139.9174175.900000111.8V88 A118 F119V88-G105 PolarHBondContact N-O 3.39Å; V88-G105 PolarHBondContact O-N 3.39Å; G105-A118 CarbonylContact C-O 3.57Å; G105-A118 VanDerWaalsContact CA-O 3.29Å; G105-A118 WeakPolarHBondContact CA-O 3.37Å; G105-F119 VanDerWaalsContact CA-CE1 3.47Å
106I79.6Confident75.8Confident54 Ų5451.8 Ų51.828%0.27731%0.308SS..EExtended strand (participates in β ladder)trans-115.4123.1179.6-57.5176000107.5T108 V117 A118I106-T108 PolarHBondContact O-N 3.18Å; I106-V117 CarbonylContact O-C 3.5Å; I106-V117 WeakPolarHBondContact O-CA 3.27Å; I106-A118 PolarHBondContact N-O 2.87Å; I106-A118 PolarHBondContact O-N 3.14Å
107V80.9Confident77.1Confident0 Ų051 Ų510%030%0.303CS..EExtended strand (participates in β ladder)trans-59.2128.4176.1179.50000109.2F81 A84 G85 D86 V88 I110 I115 S116F81-V107 HydrophobicContact CD1-CG2 4.48Å; A84-V107 CarbonylContact C-O 3.57Å; A84-V107 VanDerWaalsContact CA-O 3.28Å; A84-V107 WeakPolarHBondContact CA-O 3.42Å; G85-V107 PolarHBondContact N-O 3.34Å; D86-V107 HydrophobicContact CB-CG2 4.21Å; D86-V107 PolarHBondContact O-N 3.16Å; V88-V107 HydrophobicContact CB-CG2 4.37Å; V88-V107 HydrophobicContact CG1-CG2 3.52Å; V88-V107 HydrophobicContact CG2-CG2 3.87Å; V107-I110 HydrophobicContact CG1-CD1 4.06Å; V107-I110 HydrophobicContact CG1-CG1 3.7Å; V107-I115 HydrophobicContact CG1-CD1 4.08Å; V107-I115 HydrophobicContact CG1-CG1 4.07Å; V107-I115 HydrophobicContact CG2-CD1 4.1Å; V107-S116 CarbonylContact C-O 3.56Å; V107-S116 WeakPolarHBondContact CA-O 3.44Å
108T73.4Confident78Confident14 Ų1448.3 Ų48.39%0.08628%0.284CS..EExtended strand (participates in β ladder)trans-105.7-30.7177.649.90000112.8I106 S116 A118 H267 A269I106-T108 PolarHBondContact O-N 3.18Å; T108-S116 PolarHBondContact N-O 2.95Å; T108-S116 VanDerWaalsContact OG1-CB 3.24Å; T108-S116 WeakPolarHBondContact OG1-CB 3.4Å; T108-S116 PolarHBondContact OG1-O 3.2Å; T108-A118 HydrophobicContact CG2-CB 3.4Å; T108-H267 WeakPolarHBondContact CB-NE2 3.37Å; T108-H267 WeakPolarHBondContact CG2-NE2 3.34Å; T108-H267 PolarHBondContact O-CE1 3.04Å; T108-H267 PolarHBondContact O-ND1 3.06Å; T108-A269 WeakPolarHBondContact O-CB 3.48Å
109R73.5Confident78.9Confident162 Ų16244.3 Ų44.361%0.61125%0.25SS*.EExtended strand (participates in β ladder)trans-155144.5179.4-171.4178.1-179.2-179.21.8109.9P83 S116 A269P83-R109 VanDerWaalsContact O-CA 3.28Å; P83-R109 WeakPolarHBondContact O-CA 3.48Å; R109-S116 PolarHBondContact N-O 3.18Å; R109-S116 PolarHBondContact O-N 3.37Å; R109-A269 HydrophobicContact CB-CB 4.39Å; R109-A269 HydrophobicContact CG-CB 4.42Å
110I75.5Confident79.2Confident38 Ų3844.6 Ų44.620%0.19524%0.238CC..EExtended strand (participates in β ladder)trans-123137.7167-56.7177.5000108F81 G82 V107 I115F81-I110 VanDerWaalsContact C-CD1 3.49Å; F81-I110 HydrophobicContact CB-CD1 3.41Å; F81-I110 VanDerWaalsContact CB-CD1 3.41Å; F81-I110 WeakPolarHBondContact O-CD1 3.4Å; G82-I110 VanDerWaalsContact O-CD1 3.27Å; G82-I110 WeakPolarHBondContact O-CD1 3.48Å; V107-I110 HydrophobicContact CG1-CD1 4.06Å; V107-I110 HydrophobicContact CG1-CG1 3.7Å; I110-I115 HydrophobicContact CD1-CD1 4.05Å; I110-I115 HydrophobicContact CG1-CD1 3.88Å; I110-I115 HydrophobicContact CG1-CG1 4.01Å
111S75.8Confident78.6Confident43 Ų4347.1 Ų47.130%0.30125%0.25SS..  trans-124.6173.9165.778.30000109.2A113 S114S111-A113 PolarHBondContact O-N 2.76Å; S111-A113 PolarHBondContact OG-N 3.22Å; S111-A113 VanDerWaalsContact OG-N 3.16Å; S111-S114 PolarHBondContact N-O 3.45Å; S111-S114 PolarHBondContact OG-N 2.9Å; S111-S114 PolarHBondContact OG-O 3.13Å; S111-S114 PolarHBondContact OG-OG 3.5Å
112Q74.9Confident77.5Confident171 Ų17146.6 Ų46.680%0.79925%0.249SC*.SBendtrans-64.4-20.9172.7-70.3-178.7-13.300113S75 L76S75-Q112 CarbonylContact C-O 3.45Å; S75-Q112 WeakPolarHBondContact CA-O 3.17Å; S75-Q112 VanDerWaalsContact CB-O 3.3Å; S75-Q112 WeakPolarHBondContact CB-O 2.91Å; L76-Q112 PolarHBondContact N-O 2.71Å
113A81.8Confident75.9Confident46 Ų4652.7 Ų52.738%0.3827%0.273SS..SBendtrans-111.6-13-17500000114.4P67 S111P67-A113 WeakPolarHBondContact CD-O 3.15Å; S111-A113 PolarHBondContact O-N 2.76Å; S111-A113 PolarHBondContact OG-N 3.22Å; S111-A113 VanDerWaalsContact OG-N 3.16Å
114S87.1Confident73.9Confident23 Ų2358.9 Ų58.916%0.16131%0.305CS..  trans-158.8153.2-172.666.70000113.5L65 S111L65-S114 CarbonylContact O-C 3.58Å; L65-S114 VanDerWaalsContact O-CA 3.24Å; L65-S114 WeakPolarHBondContact O-CA 3.06Å; L65-S114 WeakPolarHBondContact O-CB 3.49Å; S111-S114 PolarHBondContact N-O 3.45Å; S111-S114 PolarHBondContact OG-N 2.9Å; S111-S114 PolarHBondContact OG-O 3.13Å; S111-S114 PolarHBondContact OG-OG 3.5Å
115I87.3Confident72.1Confident0 Ų058.2 Ų58.20%032%0.315CS..EExtended strand (participates in β ladder)trans-123.7126.4173.6-176.8157.2000109.7L45 L48 L65 L76 F81 V107 I110 V117 L136L45-I115 HydrophobicContact CD1-CD1 4.14Å; L45-I115 HydrophobicContact CD1-CG2 4.14Å; L48-I115 HydrophobicContact CD1-CG2 3.9Å; L65-I115 HydrophobicContact CB-CG2 3.88Å; L65-I115 HydrophobicContact CD1-CG2 4.48Å; L65-I115 PolarHBondContact N-O 3.21Å; L65-I115 PolarHBondContact O-N 2.91Å; L76-I115 HydrophobicContact CD1-CB 4.13Å; L76-I115 HydrophobicContact CD1-CG2 4.39Å; F81-I115 HydrophobicContact CB-CD1 4.29Å; F81-I115 HydrophobicContact CD1-CD1 4.31Å; F81-I115 HydrophobicContact CG-CD1 4.29Å; V107-I115 HydrophobicContact CG1-CD1 4.08Å; V107-I115 HydrophobicContact CG1-CG1 4.07Å; V107-I115 HydrophobicContact CG2-CD1 4.1Å; I110-I115 HydrophobicContact CD1-CD1 4.05Å; I110-I115 HydrophobicContact CG1-CD1 3.88Å; I110-I115 HydrophobicContact CG1-CG1 4.01Å; I115-V117 HydrophobicContact CG1-CG2 4.41Å; I115-L136 HydrophobicContact CD1-CD2 3.67Å; I115-L136 HydrophobicContact CG1-CD2 4.23Å; I115-L136 HydrophobicContact CG2-CD2 4.01Å
116S86.9Confident70.6Confident12 Ų1259.5 Ų59.58%0.08433%0.325CS..EExtended strand (participates in β ladder)trans-99.6134179-51.30000109.8I63 V107 T108 R109I63-S116 CarbonylContact O-C 3.58Å; I63-S116 WeakPolarHBondContact O-CA 3.42Å; V107-S116 CarbonylContact C-O 3.56Å; V107-S116 WeakPolarHBondContact CA-O 3.44Å; T108-S116 PolarHBondContact N-O 2.95Å; T108-S116 VanDerWaalsContact OG1-CB 3.24Å; T108-S116 WeakPolarHBondContact OG1-CB 3.4Å; T108-S116 PolarHBondContact OG1-O 3.2Å; R109-S116 PolarHBondContact N-O 3.18Å; R109-S116 PolarHBondContact O-N 3.37Å
117V86.7Confident69.6Low0 Ų062.2 Ų62.20%035%0.349CS..EExtended strand (participates in β ladder)trans-131.3130.5-178.7-171.40000109.5V62 I63 L65 V88 I106 I115 F119 L136V62-V117 WeakPolarHBondContact CA-O 3.43Å; I63-V117 PolarHBondContact N-O 2.91Å; I63-V117 PolarHBondContact O-N 2.82Å; L65-V117 HydrophobicContact CD1-CG2 4.33Å; V88-V117 HydrophobicContact CG2-CB 4.46Å; V88-V117 HydrophobicContact CG2-CG1 3.54Å; V88-V117 HydrophobicContact CG2-CG2 3.99Å; I106-V117 CarbonylContact O-C 3.5Å; I106-V117 WeakPolarHBondContact O-CA 3.27Å; I115-V117 HydrophobicContact CG1-CG2 4.41Å; V117-F119 HydrophobicContact CB-CE2 3.8Å; V117-F119 HydrophobicContact CB-CZ 3.83Å; V117-F119 HydrophobicContact CG1-CE1 4.07Å; V117-F119 HydrophobicContact CG1-CE2 3.7Å; V117-F119 HydrophobicContact CG1-CZ 3.36Å; V117-F119 WeakPolarHBondContact O-CE2 3.35Å; V117-L136 HydrophobicContact CG2-CD1 4.32Å; V117-L136 HydrophobicContact CG2-CD2 4.41Å
118A81.9Confident68.9Low6 Ų663.7 Ų63.75%0.0536%0.355CS..EExtended strand (participates in β ladder)trans-97.7142.3174.500000112.2T61 V62 G105 I106 T108T61-A118 CarbonylContact O-C 3.55Å; T61-A118 WeakPolarHBondContact O-CA 3.47Å; V62-A118 HydrophobicContact CG2-CB 4.17Å; G105-A118 CarbonylContact C-O 3.57Å; G105-A118 VanDerWaalsContact CA-O 3.29Å; G105-A118 WeakPolarHBondContact CA-O 3.37Å; I106-A118 PolarHBondContact N-O 2.87Å; I106-A118 PolarHBondContact O-N 3.14Å; T108-A118 HydrophobicContact CG2-CB 3.4Å
119F80.8Confident68.6Low3 Ų367.9 Ų67.91%0.01338%0.377CS..EExtended strand (participates in β ladder)trans-121.2125.9179.4-59.5-85.5000109.6R60 T61 I63 I90 C103 T104 G105 V117 D121 L122R60-F119 WeakPolarHBondContact CB-O 3.03Å; T61-F119 PolarHBondContact N-O 2.92Å; T61-F119 VanDerWaalsContact N-O 3.14Å; T61-F119 PolarHBondContact O-N 2.83Å; I63-F119 HydrophobicContact CB-CE2 4.1Å; I63-F119 HydrophobicContact CD1-CD2 3.93Å; I63-F119 HydrophobicContact CD1-CE2 3.77Å; I63-F119 HydrophobicContact CG1-CD2 4.09Å; I63-F119 HydrophobicContact CG1-CE2 3.97Å; I90-F119 HydrophobicContact CD1-CE1 4.18Å; I90-F119 HydrophobicContact CD1-CE2 4.26Å; I90-F119 HydrophobicContact CD1-CZ 3.45Å; I90-F119 VanDerWaalsContact CD1-CZ 3.45Å; I90-F119 HydrophobicContact CG1-CZ 4.16Å; C103-F119 HydrophobicContact CB-CD1 4.36Å; C103-F119 HydrophobicContact CB-CE1 4.33Å; C103-F119 WeakPolarHBondContact SG-CE1 3.45Å; T104-F119 VanDerWaalsContact O-CD1 3.25Å; T104-F119 WeakPolarHBondContact O-CD1 3.44Å; G105-F119 VanDerWaalsContact CA-CE1 3.47Å; V117-F119 HydrophobicContact CB-CE2 3.8Å; V117-F119 HydrophobicContact CB-CZ 3.83Å; V117-F119 HydrophobicContact CG1-CE1 4.07Å; V117-F119 HydrophobicContact CG1-CE2 3.7Å; V117-F119 HydrophobicContact CG1-CZ 3.36Å; V117-F119 WeakPolarHBondContact O-CE2 3.35Å; F119-D121 PolarHBondContact O-N 3.25Å; F119-L122 HydrophobicContact CB-CD2 4.27Å; F119-L122 HydrophobicContact CG-CD2 4.35Å
120D64.3Low68.2Low106 Ų10663.1 Ų63.157%0.56737%0.368SS*.SBendtrans-70.2114162.3-85.5-42.1000107.8R60R60-D120 IonicContact CZ-OD1 3.93Å; R60-D120 IonicContact CZ-OD2 3.9Å; R60-D120 IonicContact NE-OD1 3.51Å; R60-D120 PolarHBondContact NE-OD1 3.25Å; R60-D120 IonicContact NE-OD2 3.64Å; R60-D120 VanDerWaalsContact NH2-CG 3.29Å; R60-D120 IonicContact NH2-OD1 3.66Å; R60-D120 PolarHBondContact NH2-OD1 3.17Å; R60-D120 VanDerWaalsContact NH2-OD1 3.12Å; R60-D120 IonicContact NH2-OD2 2.65Å; R60-D120 PolarHBondContact NH2-OD2 3.44Å
121D58.3Low67.9Low74 Ų7467.5 Ų67.540%0.39639%0.392SS..SBendtrans18.2101.2-179.8-81.6-42.7000115.3F119 K123 R327 R331F119-D121 PolarHBondContact O-N 3.25Å; D121-K123 PolarHBondContact O-N 2.69Å; D121-R327 IonicContact OD1-CZ 2.75Å; D121-R327 IonicContact OD1-NH1 3.46Å; D121-R327 PolarHBondContact OD1-NH1 2.84Å; D121-R331 IonicContact OD2-NH1 2.7Å
122L57.6Low67.8Low54 Ų5466.1 Ų66.128%0.28339%0.385SS..  trans-46.799.4175.4-68.7166.3000110.8F119 D124 A126 F128F119-L122 HydrophobicContact CB-CD2 4.27Å; F119-L122 HydrophobicContact CG-CD2 4.35Å; L122-D124 PolarHBondContact O-N 3.09Å; L122-A126 HydrophobicContact CD2-CB 4.32Å; L122-F128 HydrophobicContact CD1-CD2 4.43Å; L122-F128 HydrophobicContact CD1-CE2 3.9Å; L122-F128 HydrophobicContact CD2-CE2 3.59Å; L122-F128 HydrophobicContact CD2-CZ 3.99Å; L122-F128 HydrophobicContact CG-CE2 4.41Å
123K44.5Very low68.3Low190 Ų19059.8 Ų59.883%0.82636%0.357SS*.  trans-57.2136.1179.7-71.1-171.4176.3-174.70109D121 G125D121-K123 PolarHBondContact O-N 2.69Å; K123-G125 PolarHBondContact O-N 2.98Å
124D40Very low68.6Low152 Ų15258.5 Ų58.581%0.81334%0.342SS*.THydrogen-bonded Turntrans-29.4109.5-162.8-66.3-72.3000116.1L122 K320L122-D124 PolarHBondContact O-N 3.09Å; D124-K320 IonicContact OD1-NZ 3.61Å
125G43.2Very low68.7Low71 Ų7157.7 Ų57.773%0.73234%0.336SS*.THydrogen-bonded Turntrans122.7-16.3160.700000117K123 S127K123-G125 PolarHBondContact O-N 2.98Å; G125-S127 VanDerWaalsContact C-N 3.32Å; G125-S127 PolarHBondContact O-N 3.1Å
126A48.7Very low68.7Low30 Ų3057.7 Ų57.725%0.24834%0.336CS..  trans-73.577.4-179.400000113I102 L122I102-A126 HydrophobicContact CG2-CB 4.43Å; L122-A126 HydrophobicContact CD2-CB 4.32Å
127S57.9Low68.7Low112 Ų11257.4 Ų57.478%0.78333%0.333SS*.  trans-80.6112.2164.858.30000109.8G125G125-S127 VanDerWaalsContact C-N 3.32Å; G125-S127 PolarHBondContact O-N 3.1Å
128F67.1Low68.6Low31 Ų3160.5 Ų60.514%0.13635%0.347CS..  trans-72.8137.5169.2-54.1-91.8000110.7I50 I63 I90 I102 L122 Y134I50-F128 HydrophobicContact CD1-CB 3.25Å; I50-F128 HydrophobicContact CD1-CD1 3.98Å; I50-F128 HydrophobicContact CD1-CG 3.71Å; I63-F128 HydrophobicContact CD1-CD2 3.48Å; I63-F128 VanDerWaalsContact CD1-CD2 3.48Å; I63-F128 HydrophobicContact CD1-CE1 4.32Å; I63-F128 HydrophobicContact CD1-CE2 3.19Å; I63-F128 HydrophobicContact CD1-CG 4.16Å; I63-F128 HydrophobicContact CD1-CZ 3.65Å; I90-F128 HydrophobicContact CD1-CE1 4.04Å; I90-F128 HydrophobicContact CD1-CZ 4.44Å; I90-F128 HydrophobicContact CG2-CE1 4.27Å; I102-F128 HydrophobicContact CG2-CE1 4.29Å; L122-F128 HydrophobicContact CD1-CD2 4.43Å; L122-F128 HydrophobicContact CD1-CE2 3.9Å; L122-F128 HydrophobicContact CD2-CE2 3.59Å; L122-F128 HydrophobicContact CD2-CZ 3.99Å; L122-F128 HydrophobicContact CG-CE2 4.41Å; F128-Y134 HydrophobicContact CD1-CE1 4.15Å; F128-Y134 HydrophobicContact CD1-CE2 4.35Å; F128-Y134 AromaticContact CD1-CZ 3.95Å
129D66.9Low68.4Low102 Ų10261.8 Ų61.855%0.54535%0.353SS..  trans-83143.2170.7-163.7-8.7000109.3D131 G132 Y134D129-D131 PolarHBondContact OD1-N 3.26Å; D129-G132 PolarHBondContact O-N 3.06Å; D129-Y134 PolarHBondContact N-OH 3.18Å
130S66Low68Low61 Ų6163 Ų6343%0.42736%0.363SS..SBendtrans-77.7-25.5-177.6-52.70000111.9Q49Q49-S130 WeakPolarHBondContact CG-O 3.37Å; Q49-S130 PolarHBondContact NE2-O 3.2Å
131D67.4Low68.3Low130 Ų13060 Ų6070%0.69535%0.347SS*.SBendtrans-97.71.5172-71.5-34.9000113.2Q49 D129Q49-D131 PolarHBondContact NE2-OD1 2.87Å; D129-D131 PolarHBondContact OD1-N 3.26Å
132G75.8Confident69Low14 Ų1458.4 Ų58.414%0.14434%0.338CS..  trans-63.7138.4173.300000112D129D129-G132 PolarHBondContact O-N 3.06Å
133L84.6Confident70.1Confident39 Ų3958.3 Ų58.320%0.20434%0.34CS..EExtended strand (participates in β ladder)trans-88.7150.6163.9-65.4177.1000109.2L48 R68 P93L48-L133 CarbonylContact O-C 3.51Å; L48-L133 WeakPolarHBondContact O-CA 3.32Å; R68-L133 HydrophobicContact CG-CD2 4.45Å; P93-L133 HydrophobicContact CB-CB 4.4Å; P93-L133 WeakPolarHBondContact CD-O 3.46Å; P93-L133 HydrophobicContact CG-CB 4.23Å
134Y87.9Confident71.9Confident18 Ų1851.1 Ų51.17%0.07131%0.312CS..EExtended strand (participates in β ladder)trans-142146.2-179.2-63.9-68.9000110.9K47 L48 I50 I90 I102 F128 D129K47-Y134 PolarHBondContact N-O 3.24Å; L48-Y134 PolarHBondContact N-O 3.17Å; L48-Y134 PolarHBondContact O-N 3.18Å; I50-Y134 HydrophobicContact CD1-CD2 4.26Å; I50-Y134 HydrophobicContact CD1-CE2 3.76Å; I50-Y134 HydrophobicContact CG1-CD2 4.15Å; I50-Y134 HydrophobicContact CG1-CE2 4.04Å; I90-Y134 HydrophobicContact CG2-CD1 3.79Å; I90-Y134 HydrophobicContact CG2-CG 4.11Å; I102-Y134 HydrophobicContact CD1-CD1 3.74Å; I102-Y134 HydrophobicContact CD1-CE1 3.57Å; F128-Y134 HydrophobicContact CD1-CE1 4.15Å; F128-Y134 HydrophobicContact CD1-CE2 4.35Å; F128-Y134 AromaticContact CD1-CZ 3.95Å; D129-Y134 PolarHBondContact N-OH 3.18Å
135N88.8Confident74.2Confident6 Ų645.1 Ų45.13%0.03228%0.278CS..EExtended strand (participates in β ladder)trans-103.9141.8168.9-61.8-38.6000109.1L46 K47 I90 Y91 D92 P93 C96L46-N135 WeakPolarHBondContact CA-OD1 3.17Å; L46-N135 HydrophobicContact CD2-CB 4.14Å; K47-N135 PolarHBondContact N-OD1 3.28Å; I90-N135 WeakPolarHBondContact CA-O 3.45Å; Y91-N135 PolarHBondContact N-O 3.14Å; Y91-N135 PolarHBondContact O-N 2.79Å; D92-N135 PolarHBondContact O-ND2 2.8Å; P93-N135 WeakPolarHBondContact CA-ND2 3.3Å; C96-N135 VanDerWaalsContact SG-CB 3.58Å
136L88.2Confident76.3Confident0 Ų047 Ų470%027%0.266CS..EExtended strand (participates in β ladder)trans-118.2125.5177.8-164.276.8000109.4C44 L45 L48 L65 F81 V88 G89 I90 I115 V117C44-L136 CarbonylContact C-O 3.59Å; C44-L136 WeakPolarHBondContact CA-O 3.1Å; C44-L136 PolarHBondContact SG-O 2.88Å; L45-L136 HydrophobicContact CB-CB 4.29Å; L45-L136 HydrophobicContact CD1-CD2 4.36Å; L45-L136 PolarHBondContact N-O 3.01Å; L45-L136 PolarHBondContact O-N 3.44Å; L48-L136 HydrophobicContact CD1-CB 4.06Å; L65-L136 HydrophobicContact CD1-CD1 4.14Å; F81-L136 HydrophobicContact CE1-CD2 4.13Å; F81-L136 HydrophobicContact CE1-CG 4.36Å; V88-L136 HydrophobicContact CB-CD1 3.83Å; V88-L136 HydrophobicContact CB-CD2 4.42Å; V88-L136 HydrophobicContact CB-CG 4.01Å; V88-L136 HydrophobicContact CG1-CD2 4.36Å; V88-L136 HydrophobicContact CG1-CG 4.32Å; V88-L136 HydrophobicContact CG2-CD1 3.81Å; V88-L136 HydrophobicContact CG2-CG 4.37Å; G89-L136 WeakPolarHBondContact O-CA 3.48Å; I90-L136 HydrophobicContact CD1-CD1 4.47Å; I90-L136 HydrophobicContact CG1-CD1 3.6Å; I115-L136 HydrophobicContact CD1-CD2 3.67Å; I115-L136 HydrophobicContact CG1-CD2 4.23Å; I115-L136 HydrophobicContact CG2-CD2 4.01Å; V117-L136 HydrophobicContact CG2-CD1 4.32Å; V117-L136 HydrophobicContact CG2-CD2 4.41Å
137L87.1Confident78.3Confident6 Ų649 Ų493%0.03127%0.267CS..EExtended strand (participates in β ladder)trans-123.9135.2179.4-17566.4000110Q30 C44 V88 G89 Y91 C96 L139Q30-L137 HydrophobicContact CG-CD2 4.06Å; C44-L137 HydrophobicContact CB-CD1 3.77Å; V88-L137 CarbonylContact C-O 3.59Å; V88-L137 VanDerWaalsContact CA-O 3.27Å; V88-L137 WeakPolarHBondContact CA-O 3.35Å; G89-L137 PolarHBondContact N-O 2.87Å; G89-L137 PolarHBondContact O-N 2.93Å; Y91-L137 HydrophobicContact CD2-CB 4.13Å; Y91-L137 HydrophobicContact CE2-CB 3.68Å; Y91-L137 HydrophobicContact CE2-CD2 4.29Å; C96-L137 HydrophobicContact CB-CD2 4.18Å; L137-L139 HydrophobicContact CD2-CD2 4.5Å
138K84.2Confident80Confident66 Ų6643.8 Ų43.829%0.28723%0.231SC..EExtended strand (participates in β ladder)trans-70.8131.9173-175.7161.9169.7156.50110.1V43 S80 F81 D86V43-K138 WeakPolarHBondContact O-CB 3.49Å; V43-K138 PolarHBondContact O-N 3.22Å; V43-K138 VanDerWaalsContact O-N 3.1Å; S80-K138 PolarHBondContact O-NZ 2.72Å; F81-K138 HydrophobicContact CD1-CB 4.23Å; F81-K138 HydrophobicContact CE1-CB 3.77Å; F81-K138 HydrophobicContact CZ-CB 4.17Å; D86-K138 IonicContact OD1-NZ 3.16Å; D86-K138 VanDerWaalsContact OD2-CE 3.23Å; D86-K138 WeakPolarHBondContact OD2-CE 3.48Å; D86-K138 IonicContact OD2-NZ 2.65Å; D86-K138 PolarHBondContact OD2-NZ 3.48Å
139L78.4Confident81.2Confident33 Ų3347.1 Ų47.117%0.17325%0.245CC..EExtended strand (participates in β ladder)trans-115.6153.8-177.6-59.5-179.3000111.5I87 T104 L137I87-L139 HydrophobicContact CG2-CB 4.21Å; I87-L139 HydrophobicContact CG2-CD1 4.42Å; I87-L139 PolarHBondContact O-N 3.23Å; T104-L139 HydrophobicContact CG2-CD1 3.92Å; L137-L139 HydrophobicContact CD2-CD2 4.5Å
140A71.3Confident82.5Confident27 Ų2747.3 Ų47.322%0.22324%0.238CC..  trans-55.7139.3171.800000111.4E22 I23 D142E22-A140 HydrophobicContact CG-CB 4.15Å; E22-A140 WeakPolarHBondContact OE1-CA 3.36Å; E22-A140 WeakPolarHBondContact OE1-CB 3.35Å; I23-A140 HydrophobicContact CG1-CB 4.46Å; A140-D142 PolarHBondContact O-N 3.27Å
141N69.6Low83.8Confident44 Ų4444.8 Ų44.824%0.23522%0.221CC..  trans-8872.2-170.1-167.8-13.5000112.7E22 I87 V143 T144E22-N141 PolarHBondContact OE1-N 2.81Å; I87-N141 VanDerWaalsContact CD1-OD1 3.31Å; I87-N141 WeakPolarHBondContact CD1-OD1 3.46Å; N141-V143 PolarHBondContact O-N 3.4Å; N141-V143 PolarHBondContact OD1-N 2.92Å; N141-T144 WeakPolarHBondContact O-CB 3.37Å; N141-T144 PolarHBondContact O-N 2.82Å
142D74.3Confident85.1Confident41 Ų4138.6 Ų38.622%0.21919%0.188CC..Hα-helixtrans-60-18.1-179.3-164.933.4000113.9R19 A140 K146R19-D142 IonicContact CZ-OD1 2.67Å; R19-D142 VanDerWaalsContact CZ-OD1 3.22Å; R19-D142 IonicContact NE-OD1 2.82Å; R19-D142 PolarHBondContact NE-OD1 3.46Å; R19-D142 IonicContact NH2-OD1 2.89Å; R19-D142 PolarHBondContact NH2-OD1 3.29Å; R19-D142 IonicContact NH2-OD2 3.55Å; R19-D142 PolarHBondContact NH2-OD2 3.42Å; A140-D142 PolarHBondContact O-N 3.27Å; D142-K146 WeakPolarHBondContact O-CB 3.42Å; D142-K146 WeakPolarHBondContact O-CD 3.35Å; D142-K146 VanDerWaalsContact O-CG 3.27Å; D142-K146 WeakPolarHBondContact O-CG 3.29Å; D142-K146 PolarHBondContact O-N 2.8Å; D142-K146 WeakPolarHBondContact OD2-CE 3.29Å; D142-K146 IonicContact OD2-NZ 2.69Å; D142-K146 PolarHBondContact OD2-NZ 3.03Å
143V79.6Confident86Confident52 Ų5241.9 Ų41.932%0.31520%0.202SC..Hα-helixtrans-67.8-35.7175.1174.60000111.3I87 N141 K146 R147I87-V143 HydrophobicContact CD1-CB 4.19Å; I87-V143 HydrophobicContact CD1-CG2 3.67Å; N141-V143 PolarHBondContact O-N 3.4Å; N141-V143 PolarHBondContact OD1-N 2.92Å; V143-K146 PolarHBondContact O-N 2.97Å; V143-R147 HydrophobicContact CG1-CG 4.47Å; V143-R147 VanDerWaalsContact O-CG 3.31Å; V143-R147 WeakPolarHBondContact O-CG 3.5Å; V143-R147 PolarHBondContact O-N 3.34Å
144T83Confident86.4Confident39 Ų3943 Ų4324%0.23921%0.211CC..Hα-helixtrans-63-50.7177.4-63.60000110.9N141 K146 R147 M148 T353N141-T144 WeakPolarHBondContact O-CB 3.37Å; N141-T144 PolarHBondContact O-N 2.82Å; T144-K146 PolarHBondContact O-N 3.49Å; T144-R147 PolarHBondContact O-N 3.29Å; T144-R147 VanDerWaalsContact O-N 3.16Å; T144-M148 HydrophobicContact CG2-CE 3.9Å; T144-M148 HydrophobicContact CG2-SD 4.37Å; T144-M148 PolarHBondContact O-N 2.93Å; T144-T353 HydrophobicContact CG2-CG2 3.86Å
145Y87.5Confident86.7Confident25 Ų2542.2 Ų42.210%0.09821%0.207CC..Hα-helixtrans-60-43.8175.7-63.9-83.6000112.5E18 R19 E22 R147 M148 K149E18-Y145 HydrophobicContact CB-CE1 4.5Å; E18-Y145 HydrophobicContact CG-CE1 4.12Å; R19-Y145 HydrophobicContact CB-CD1 3.74Å; R19-Y145 HydrophobicContact CB-CD2 4.4Å; R19-Y145 HydrophobicContact CB-CE1 3.69Å; R19-Y145 HydrophobicContact CB-CE2 4.36Å; R19-Y145 HydrophobicContact CB-CG 4.1Å; R19-Y145 HydrophobicContact CG-CD1 4.24Å; R19-Y145 HydrophobicContact CG-CD2 4.14Å; R19-Y145 HydrophobicContact CG-CE1 4.45Å; R19-Y145 HydrophobicContact CG-CE2 4.35Å; R19-Y145 HydrophobicContact CG-CG 4.08Å; E22-Y145 WeakPolarHBondContact OE2-CE2 3.44Å; E22-Y145 VanDerWaalsContact OE2-CZ 3.3Å; E22-Y145 PolarHBondContact OE2-OH 2.76Å; Y145-R147 VanDerWaalsContact C-N 3.26Å; Y145-R147 PolarHBondContact O-N 3.3Å; Y145-M148 HydrophobicContact CD1-CE 4Å; Y145-M148 HydrophobicContact CE1-CE 4.41Å; Y145-M148 HydrophobicContact CG-CE 4.45Å; Y145-M148 PolarHBondContact O-N 3.12Å; Y145-K149 VanDerWaalsContact O-CB 3.26Å; Y145-K149 WeakPolarHBondContact O-CB 3.38Å; Y145-K149 PolarHBondContact O-N 2.96Å
146K88.8Confident86.9Confident111 Ų11145.2 Ų45.248%0.48322%0.223SC..Hα-helixtrans-62.8-28.4176.6-76.8167.1173.9161.20113.7D142 V143 T144 R150D142-K146 WeakPolarHBondContact O-CB 3.42Å; D142-K146 WeakPolarHBondContact O-CD 3.35Å; D142-K146 VanDerWaalsContact O-CG 3.27Å; D142-K146 WeakPolarHBondContact O-CG 3.29Å; D142-K146 PolarHBondContact O-N 2.8Å; D142-K146 WeakPolarHBondContact OD2-CE 3.29Å; D142-K146 IonicContact OD2-NZ 2.69Å; D142-K146 PolarHBondContact OD2-NZ 3.03Å; V143-K146 PolarHBondContact O-N 2.97Å; T144-K146 PolarHBondContact O-N 3.49Å; K146-R150 WeakPolarHBondContact O-CB 3.49Å; K146-R150 WeakPolarHBondContact O-CG 3.42Å; K146-R150 PolarHBondContact O-N 3.48Å; K146-R150 PolarHBondContact O-NE 2.65Å
147R90.3Very high86.9Confident71 Ų7147.6 Ų47.627%0.26825%0.248SC..Hα-helixtrans-76.5-48.6173.9-72.4173.5-175.3-173.53.5111.3V143 T144 Y145 K149 R150 A151 T353 C356 I387V143-R147 HydrophobicContact CG1-CG 4.47Å; V143-R147 VanDerWaalsContact O-CG 3.31Å; V143-R147 WeakPolarHBondContact O-CG 3.5Å; V143-R147 PolarHBondContact O-N 3.34Å; T144-R147 PolarHBondContact O-N 3.29Å; T144-R147 VanDerWaalsContact O-N 3.16Å; Y145-R147 VanDerWaalsContact C-N 3.26Å; Y145-R147 PolarHBondContact O-N 3.3Å; R147-K149 PolarHBondContact O-N 3.29Å; R147-R150 PolarHBondContact O-N 2.94Å; R147-A151 PolarHBondContact O-N 2.82Å; R147-T353 VanDerWaalsContact CD-O 3.28Å; R147-T353 WeakPolarHBondContact CD-O 3.33Å; R147-T353 PolarHBondContact NH1-O 3.24Å; R147-C356 HydrophobicContact CG-CB 4.07Å; R147-C356 PolarHBondContact NE-SG 3.49Å; R147-C356 VanDerWaalsContact NE-SG 3.4Å; R147-I387 HydrophobicContact CB-CD1 4.12Å
148M92.8Very high87Confident4 Ų449.5 Ų49.52%0.0226%0.255CS..Hα-helixtrans-60.6-46.2177.1-65-175.5-58.200111.9L15 T144 Y145 R150 A151 L152 L381 S383 I387L15-M148 HydrophobicContact CD1-CB 3.9Å; L15-M148 HydrophobicContact CD1-CE 4.43Å; L15-M148 HydrophobicContact CD2-CE 3.64Å; L15-M148 HydrophobicContact CD2-SD 4.36Å; T144-M148 HydrophobicContact CG2-CE 3.9Å; T144-M148 HydrophobicContact CG2-SD 4.37Å; T144-M148 PolarHBondContact O-N 2.93Å; Y145-M148 HydrophobicContact CD1-CE 4Å; Y145-M148 HydrophobicContact CE1-CE 4.41Å; Y145-M148 HydrophobicContact CG-CE 4.45Å; Y145-M148 PolarHBondContact O-N 3.12Å; M148-R150 VanDerWaalsContact C-N 3.3Å; M148-R150 PolarHBondContact O-N 2.98Å; M148-A151 PolarHBondContact O-N 3.48Å; M148-L152 WeakPolarHBondContact O-CG 3.29Å; M148-L152 PolarHBondContact O-N 3.14Å; M148-L381 HydrophobicContact SD-CD1 4.3Å; M148-S383 PolarHBondContact SD-OG 3.37Å; M148-I387 HydrophobicContact CG-CD1 4.14Å
149K94Very high86.7Confident100 Ų10057 Ų5744%0.43528%0.282SS..Hα-helixtrans-58-39.1175.5176.2155.9-173166.10112.7L12 Y145 R147 N153L12-K149 HydrophobicContact CD2-CB 4.05Å; L12-K149 HydrophobicContact CD2-CD 4.19Å; L12-K149 HydrophobicContact CD2-CG 3.69Å; Y145-K149 VanDerWaalsContact O-CB 3.26Å; Y145-K149 WeakPolarHBondContact O-CB 3.38Å; Y145-K149 PolarHBondContact O-N 2.96Å; R147-K149 PolarHBondContact O-N 3.29Å; K149-N153 PolarHBondContact O-N 3.49Å; K149-N153 PolarHBondContact O-OD1 3.05Å
150R92.9Very high86.8Confident107 Ų10761.5 Ų61.540%0.40431%0.311SS..Hα-helixtrans-71.9-42.2176.6-79.1-177.2-68.6159.46.5112.5K146 R147 M148 L152 N153 V154 D358K146-R150 WeakPolarHBondContact O-CB 3.49Å; K146-R150 WeakPolarHBondContact O-CG 3.42Å; K146-R150 PolarHBondContact O-N 3.48Å; K146-R150 PolarHBondContact O-NE 2.65Å; R147-R150 PolarHBondContact O-N 2.94Å; M148-R150 VanDerWaalsContact C-N 3.3Å; M148-R150 PolarHBondContact O-N 2.98Å; R150-L152 VanDerWaalsContact C-N 3.31Å; R150-L152 PolarHBondContact O-N 2.95Å; R150-N153 PolarHBondContact O-N 3.39Å; R150-V154 WeakPolarHBondContact O-CG2 3.11Å; R150-V154 PolarHBondContact O-N 3.24Å; R150-D358 IonicContact CZ-OD1 2.83Å; R150-D358 IonicContact CZ-OD2 3.45Å; R150-D358 IonicContact NH1-OD1 2.8Å; R150-D358 PolarHBondContact NH1-OD1 2.85Å; R150-D358 IonicContact NH1-OD2 3.57Å; R150-D358 PolarHBondContact NH1-OD2 2.72Å; R150-D358 IonicContact NH2-OD1 2.74Å; R150-D358 IonicContact NH2-OD2 2.79Å; R150-D358 PolarHBondContact NH2-OD2 2.84Å
151A93.5Very high87.5Confident8 Ų861.6 Ų61.67%0.06632%0.315CS..Hα-helixtrans-59.7-41.5174.500000112.1R147 M148 V154 L155 I387R147-A151 PolarHBondContact O-N 2.82Å; M148-A151 PolarHBondContact O-N 3.48Å; A151-V154 PolarHBondContact O-N 3.28Å; A151-L155 VanDerWaalsContact O-CB 3.28Å; A151-L155 WeakPolarHBondContact O-CB 3.39Å; A151-L155 PolarHBondContact O-N 3.44Å; A151-I387 HydrophobicContact CB-CB 4.39Å; A151-I387 HydrophobicContact CB-CG1 3.7Å
152L95.1Very high88.2Confident0 Ų061 Ų610%031%0.313CS..Hα-helixtrans-64.1-39.4174-70.2172000113F7 V8 T11 L12 L15 M148 R150 L155 N156F7-L152 HydrophobicContact CE1-CD2 3.86Å; F7-L152 HydrophobicContact CZ-CD2 4.44Å; V8-L152 HydrophobicContact CG1-CB 4.16Å; V8-L152 HydrophobicContact CG2-CD2 4.44Å; T11-L152 HydrophobicContact CG2-CD1 3.75Å; T11-L152 HydrophobicContact CG2-CD2 4.33Å; L12-L152 HydrophobicContact CD2-CB 4.11Å; L12-L152 HydrophobicContact CD2-CD1 3.83Å; L12-L152 HydrophobicContact CG-CB 4.38Å; L12-L152 HydrophobicContact CG-CD1 4.12Å; L15-L152 HydrophobicContact CD1-CD1 3.65Å; M148-L152 WeakPolarHBondContact O-CG 3.29Å; M148-L152 PolarHBondContact O-N 3.14Å; R150-L152 VanDerWaalsContact C-N 3.31Å; R150-L152 PolarHBondContact O-N 2.95Å; L152-L155 HydrophobicContact CD2-CD2 4.33Å; L152-L155 WeakPolarHBondContact O-CB 3.43Å; L152-L155 PolarHBondContact O-N 3.33Å; L152-N156 PolarHBondContact O-N 3.32Å
153N94.3Very high89Confident82 Ų8259 Ų5944%0.43930%0.303SS..Hα-helixtrans-66.4-40.2174.6-71.6-4.5000112.3K149 R150 N156 G157K149-N153 PolarHBondContact O-N 3.49Å; K149-N153 PolarHBondContact O-OD1 3.05Å; R150-N153 PolarHBondContact O-N 3.39Å; N153-N156 PolarHBondContact O-N 3.14Å; N153-G157 PolarHBondContact O-N 2.98Å
154V92.4Very high89.6Confident64 Ų6458.2 Ų58.239%0.38830%0.299SS..Hα-helixtrans-65-43.4175174.30000110.2R150 A151 N156 G157 Y158 L390R150-V154 WeakPolarHBondContact O-CG2 3.11Å; R150-V154 PolarHBondContact O-N 3.24Å; A151-V154 PolarHBondContact O-N 3.28Å; V154-N156 PolarHBondContact O-N 2.69Å; V154-G157 CarbonylContact O-C 3.6Å; V154-G157 PolarHBondContact O-N 2.97Å; V154-Y158 HydrophobicContact CG1-CD2 4.39Å; V154-Y158 WeakPolarHBondContact O-CB 3.41Å; V154-Y158 PolarHBondContact O-N 3.16Å; V154-L390 HydrophobicContact CB-CD1 4.26Å; V154-L390 HydrophobicContact CG1-CD1 3.96Å
155L94.1Very high90Very high0 Ų059.8 Ų59.80%031%0.312CS..Hα-helixtrans-56.5-46.4174.3174.665.6000111.8L4 F7 V8 A151 L152 G157 Y158 I167 F171 W386 L390L4-L155 HydrophobicContact CD1-CD1 3.9Å; L4-L155 HydrophobicContact CD1-CD2 4.04Å; L4-L155 HydrophobicContact CD1-CG 3.78Å; F7-L155 HydrophobicContact CD1-CD2 4.42Å; F7-L155 HydrophobicContact CE1-CD2 4.07Å; V8-L155 HydrophobicContact CG2-CD2 4.07Å; V8-L155 HydrophobicContact CG2-CG 4.33Å; A151-L155 VanDerWaalsContact O-CB 3.28Å; A151-L155 WeakPolarHBondContact O-CB 3.39Å; A151-L155 PolarHBondContact O-N 3.44Å; L152-L155 HydrophobicContact CD2-CD2 4.33Å; L152-L155 WeakPolarHBondContact O-CB 3.43Å; L152-L155 PolarHBondContact O-N 3.33Å; L155-G157 VanDerWaalsContact C-N 3.26Å; L155-G157 PolarHBondContact O-N 3.44Å; L155-Y158 VanDerWaalsContact O-CB 3.3Å; L155-Y158 WeakPolarHBondContact O-CB 3.39Å; L155-Y158 PolarHBondContact O-N 3.42Å; L155-Y158 VanDerWaalsContact O-N 3.13Å; L155-I167 HydrophobicContact CD1-CD1 3.98Å; L155-I167 HydrophobicContact CD1-CG1 4.04Å; L155-I167 HydrophobicContact CD1-CG2 4.31Å; L155-F171 HydrophobicContact CD1-CE2 4.45Å; L155-F171 HydrophobicContact CD2-CE2 4.43Å; L155-F171 HydrophobicContact CD2-CZ 4.34Å; L155-W386 HydrophobicContact CD1-CD2 4.27Å; L155-W386 HydrophobicContact CD1-CE3 3.81Å; L155-W386 HydrophobicContact CD1-CH2 4.13Å; L155-W386 HydrophobicContact CD1-CZ3 3.74Å; L155-W386 HydrophobicContact CD2-CD2 3.67Å; L155-W386 HydrophobicContact CD2-CE3 4.08Å; L155-W386 HydrophobicContact CD2-CG 3.91Å; L155-W386 HydrophobicContact CD2-CZ2 4.29Å; L155-L390 HydrophobicContact CB-CD1 4.34Å; L155-L390 HydrophobicContact CD1-CD2 3.99Å
156N92.8Very high90.4Very high69 Ų6958.6 Ų58.637%0.36931%0.307SS..Hα-helixtrans-64-31.5178.4-157.341.5000113.1E5 V8 L152 N153 V154E5-N156 WeakPolarHBondContact CA-OD1 3.33Å; V8-N156 HydrophobicContact CB-CB 4.31Å; V8-N156 HydrophobicContact CG1-CB 4.04Å; V8-N156 HydrophobicContact CG2-CB 4.09Å; L152-N156 PolarHBondContact O-N 3.32Å; N153-N156 PolarHBondContact O-N 3.14Å; V154-N156 PolarHBondContact O-N 2.69Å
157G88.5Confident90.7Very high51 Ų5153.9 Ų53.953%0.52629%0.287SS..THydrogen-bonded Turntrans-87.6-1.2175.900000114.7N153 V154 L155 R159N153-G157 PolarHBondContact O-N 2.98Å; V154-G157 CarbonylContact O-C 3.6Å; V154-G157 PolarHBondContact O-N 2.97Å; L155-G157 VanDerWaalsContact C-N 3.26Å; L155-G157 PolarHBondContact O-N 3.44Å; G157-R159 PolarHBondContact O-N 2.84Å; G157-R159 VanDerWaalsContact O-N 3.16Å
158Y89.4Confident90.8Very high45 Ų4554.3 Ų54.318%0.17629%0.292CS..  trans-75.9106.4-169.4-154.1-84000111V154 L155 G161 P162 A163 I167 L390V154-Y158 HydrophobicContact CG1-CD2 4.39Å; V154-Y158 WeakPolarHBondContact O-CB 3.41Å; V154-Y158 PolarHBondContact O-N 3.16Å; L155-Y158 VanDerWaalsContact O-CB 3.3Å; L155-Y158 WeakPolarHBondContact O-CB 3.39Å; L155-Y158 PolarHBondContact O-N 3.42Å; L155-Y158 VanDerWaalsContact O-N 3.13Å; Y158-G161 WeakPolarHBondContact OH-CA 3.34Å; Y158-P162 WeakPolarHBondContact OH-CD 3.33Å; Y158-A163 HydrophobicContact CE1-CB 4.13Å; Y158-A163 WeakPolarHBondContact OH-CB 3.47Å; Y158-A163 PolarHBondContact OH-N 2.94Å; Y158-A163 VanDerWaalsContact OH-N 3.08Å; Y158-I167 HydrophobicContact CD1-CD1 3.39Å; Y158-I167 HydrophobicContact CD2-CD1 4.47Å; Y158-I167 HydrophobicContact CE1-CD1 3.85Å; Y158-I167 HydrophobicContact CG-CD1 3.74Å; Y158-L390 HydrophobicContact CD2-CD2 3.87Å; Y158-L390 HydrophobicContact CE2-CB 4.34Å; Y158-L390 HydrophobicContact CE2-CD2 3.98Å; Y158-L390 HydrophobicContact CG-CD2 4.39Å; Y158-L390 PolarHBondContact OH-O 2.95Å
159R79Confident90.9Very high223 Ų22354.3 Ų54.384%0.84229%0.292SS*.  trans-110.3-34.7-179.6-64.7-172.6-178.6-136.5-0.8113.8G157G157-R159 PolarHBondContact O-N 2.84Å; G157-R159 VanDerWaalsContact O-N 3.16Å
160T80.8Confident90.9Very high129 Ų12949.5 Ų49.579%0.79127%0.271SS*.SBendtrans-145.4137.7-177.446.20000109.3
161G84.3Confident91Very high29 Ų2946 Ų4630%0.29926%0.259SS..SBendtrans150.8172.2-177.700000112.3Y158 A163 S164Y158-G161 WeakPolarHBondContact OH-CA 3.34Å; G161-A163 VanDerWaalsContact C-N 3.25Å; G161-A163 PolarHBondContact O-N 2.79Å; G161-S164 WeakPolarHBondContact O-CB 3.36Å; G161-S164 PolarHBondContact O-N 2.8Å; G161-S164 VanDerWaalsContact O-N 3.13Å
162P84.6Confident90.8Very high30 Ų3047.6 Ų47.620%0.19528%0.276CS..THydrogen-bonded Turntrans-59-32.5-172.521.9-34000113.7Y158 S164 E367 R393Y158-P162 WeakPolarHBondContact OH-CD 3.33Å; P162-S164 VanDerWaalsContact C-N 3.29Å; P162-S164 PolarHBondContact O-N 2.94Å; P162-E367 HydrophobicContact CB-CG 4.36Å; P162-E367 HydrophobicContact CG-CG 4.09Å; P162-R393 VanDerWaalsContact O-CA 3.31Å; P162-R393 WeakPolarHBondContact O-CA 3.46Å; P162-R393 WeakPolarHBondContact O-CB 3.44Å
163A91.9Very high90.6Very high1 Ų151.5 Ų51.51%0.00830%0.297CS..THydrogen-bonded Turntrans-83.14.4-177.800000114.2Y158 G161 L166 I167 A392Y158-A163 HydrophobicContact CE1-CB 4.13Å; Y158-A163 WeakPolarHBondContact OH-CB 3.47Å; Y158-A163 PolarHBondContact OH-N 2.94Å; Y158-A163 VanDerWaalsContact OH-N 3.08Å; G161-A163 VanDerWaalsContact C-N 3.25Å; G161-A163 PolarHBondContact O-N 2.79Å; A163-L166 WeakPolarHBondContact O-CB 3.24Å; A163-L166 PolarHBondContact O-N 2.86Å; A163-I167 HydrophobicContact CB-CD1 4.23Å; A163-I167 HydrophobicContact CB-CG1 4.48Å; A163-I167 WeakPolarHBondContact O-CD1 3.38Å; A163-I167 VanDerWaalsContact O-CG1 3.26Å; A163-I167 WeakPolarHBondContact O-CG1 3.39Å; A163-I167 PolarHBondContact O-N 3.17Å; A163-A392 WeakPolarHBondContact CA-O 3.36Å; A163-A392 WeakPolarHBondContact CB-O 3.36Å
164S91.9Very high90.4Very high34 Ų3449.5 Ų49.524%0.23829%0.292CS..Hα-helixtrans-58.6-53.9-172.9-171.90000112.9G161 P162 L166 I167 H168G161-S164 WeakPolarHBondContact O-CB 3.36Å; G161-S164 PolarHBondContact O-N 2.8Å; G161-S164 VanDerWaalsContact O-N 3.13Å; P162-S164 VanDerWaalsContact C-N 3.29Å; P162-S164 PolarHBondContact O-N 2.94Å; S164-L166 VanDerWaalsContact C-N 3.3Å; S164-L166 PolarHBondContact O-N 2.93Å; S164-I167 PolarHBondContact O-N 3.26Å; S164-H168 PolarHBondContact O-CD2 3.32Å; S164-H168 PolarHBondContact O-N 3.1Å
165S91.9Very high90.3Very high72 Ų7253.2 Ų53.250%0.50331%0.305SS..Hα-helixtrans-60.7-40.2176.7-48.70000112I167 H168 V169S165-I167 PolarHBondContact O-N 2.99Å; S165-H168 PolarHBondContact O-N 3.21Å; S165-V169 PolarHBondContact O-N 2.95Å; S165-V169 VanDerWaalsContact O-N 3.12Å
166L94.4Very high90.2Very high0 Ų054.5 Ų54.50%031%0.313CS..Hα-helixtrans-61.4-43.4177.2176.960.3000111.8A163 S164 H168 V169 L170 E208 L389 C395A163-L166 WeakPolarHBondContact O-CB 3.24Å; A163-L166 PolarHBondContact O-N 2.86Å; S164-L166 VanDerWaalsContact C-N 3.3Å; S164-L166 PolarHBondContact O-N 2.93Å; L166-H168 VanDerWaalsContact C-N 3.34Å; L166-H168 PolarHBondContact O-N 2.91Å; L166-V169 PolarHBondContact O-N 2.84Å; L166-L170 HydrophobicContact CD1-CD1 3.78Å; L166-L170 HydrophobicContact CD1-CD2 4.33Å; L166-L170 HydrophobicContact CD1-CG 3.8Å; L166-L170 HydrophobicContact CD2-CD1 4.31Å; L166-L170 HydrophobicContact CG-CD1 3.69Å; L166-L170 HydrophobicContact CG-CG 4.14Å; L166-L170 WeakPolarHBondContact O-CB 3.16Å; L166-L170 VanDerWaalsContact O-CG 3.22Å; L166-L170 WeakPolarHBondContact O-CG 3.4Å; L166-L170 PolarHBondContact O-N 2.72Å; L166-E208 HydrophobicContact CD1-CB 4.27Å; L166-E208 WeakPolarHBondContact CD1-O 3.43Å; L166-L389 HydrophobicContact CD2-CD2 4.43Å; L166-C395 HydrophobicContact CD1-CB 4.41Å; L166-C395 HydrophobicContact CD2-CB 4.02Å
167I95.2Very high90Very high13 Ų1352.9 Ų52.97%0.06731%0.307CS..Hα-helixtrans-61-43.7176.7-69.3160.1000110.4L4 L155 Y158 A163 S164 S165 V169 L170 F171 W386 L390L4-I167 HydrophobicContact CD1-CG2 4.43Å; L4-I167 HydrophobicContact CD2-CG2 4.41Å; L155-I167 HydrophobicContact CD1-CD1 3.98Å; L155-I167 HydrophobicContact CD1-CG1 4.04Å; L155-I167 HydrophobicContact CD1-CG2 4.31Å; Y158-I167 HydrophobicContact CD1-CD1 3.39Å; Y158-I167 HydrophobicContact CD2-CD1 4.47Å; Y158-I167 HydrophobicContact CE1-CD1 3.85Å; Y158-I167 HydrophobicContact CG-CD1 3.74Å; A163-I167 HydrophobicContact CB-CD1 4.23Å; A163-I167 HydrophobicContact CB-CG1 4.48Å; A163-I167 WeakPolarHBondContact O-CD1 3.38Å; A163-I167 VanDerWaalsContact O-CG1 3.26Å; A163-I167 WeakPolarHBondContact O-CG1 3.39Å; A163-I167 PolarHBondContact O-N 3.17Å; S164-I167 PolarHBondContact O-N 3.26Å; S165-I167 PolarHBondContact O-N 2.99Å; I167-V169 VanDerWaalsContact C-N 3.35Å; I167-V169 PolarHBondContact O-N 3.04Å; I167-L170 PolarHBondContact O-N 2.83Å; I167-F171 HydrophobicContact CG2-CD2 3.92Å; I167-F171 HydrophobicContact CG2-CE2 4.27Å; I167-F171 WeakPolarHBondContact O-CD2 3.14Å; I167-F171 PolarHBondContact O-N 3.44Å; I167-F171 VanDerWaalsContact O-N 3.1Å; I167-W386 HydrophobicContact CG1-CH2 4.22Å; I167-W386 HydrophobicContact CG1-CZ3 3.9Å; I167-L390 HydrophobicContact CD1-CD2 3.88Å; I167-L390 HydrophobicContact CG1-CD2 4.5Å
168H93.1Very high89.8Confident80 Ų8053.6 Ų53.637%0.3730%0.304SS..Hα-helixtrans-60.8-41.9177.7-70.8-63.2000112.6S164 S165 L166 G172 D173 A174S164-H168 PolarHBondContact O-CD2 3.32Å; S164-H168 PolarHBondContact O-N 3.1Å; S165-H168 PolarHBondContact O-N 3.21Å; L166-H168 VanDerWaalsContact C-N 3.34Å; L166-H168 PolarHBondContact O-N 2.91Å; H168-G172 PolarHBondContact O-N 3.12Å; H168-D173 HydrophobicContact CB-CB 4.11Å; H168-D173 IonicContact ND1-OD2 3.01Å; H168-D173 PolarHBondContact O-N 2.8Å; H168-A174 HydrophobicContact CB-CB 3.85Å; H168-A174 PolarHBondContact O-N 3.28Å; H168-A174 VanDerWaalsContact O-N 3.1Å
169V94.5Very high89.2Confident3 Ų355.7 Ų55.72%0.01832%0.315CS..Hα-helixtrans-66.6-45.3173.2176.90000111.3S165 L166 I167 F171 G172 A174 P176 E208 L209 Y430S165-V169 PolarHBondContact O-N 2.95Å; S165-V169 VanDerWaalsContact O-N 3.12Å; L166-V169 PolarHBondContact O-N 2.84Å; I167-V169 VanDerWaalsContact C-N 3.35Å; I167-V169 PolarHBondContact O-N 3.04Å; V169-F171 PolarHBondContact O-N 3.12Å; V169-F171 VanDerWaalsContact O-N 3.08Å; V169-G172 PolarHBondContact O-N 2.69Å; V169-G172 VanDerWaalsContact O-N 3.14Å; V169-A174 HydrophobicContact CG2-CB 4.19Å; V169-P176 HydrophobicContact CG1-CB 3.97Å; V169-E208 HydrophobicContact CB-CB 4.35Å; V169-E208 HydrophobicContact CG2-CB 4.05Å; V169-E208 HydrophobicContact CG2-CG 3.91Å; V169-L209 HydrophobicContact CG1-CB 4.31Å; V169-L209 HydrophobicContact CG1-CD2 4.36Å; V169-Y430 PolarHBondContact O-OH 2.78Å
170L94.9Very high88.3Confident0 Ų050.8 Ų50.80%032%0.315CS..Hα-helixtrans-65.6-16.4-177.8-69.7177000114.5L166 I167 L209 W386 L389 R425 L426L166-L170 HydrophobicContact CD1-CD1 3.78Å; L166-L170 HydrophobicContact CD1-CD2 4.33Å; L166-L170 HydrophobicContact CD1-CG 3.8Å; L166-L170 HydrophobicContact CD2-CD1 4.31Å; L166-L170 HydrophobicContact CG-CD1 3.69Å; L166-L170 HydrophobicContact CG-CG 4.14Å; L166-L170 WeakPolarHBondContact O-CB 3.16Å; L166-L170 VanDerWaalsContact O-CG 3.22Å; L166-L170 WeakPolarHBondContact O-CG 3.4Å; L166-L170 PolarHBondContact O-N 2.72Å; I167-L170 PolarHBondContact O-N 2.83Å; L170-L209 HydrophobicContact CD2-CD1 4.25Å; L170-L209 HydrophobicContact CD2-CD2 4.19Å; L170-W386 HydrophobicContact CB-CH2 3.88Å; L170-W386 HydrophobicContact CB-CZ2 4.24Å; L170-W386 HydrophobicContact CD1-CH2 3.39Å; L170-W386 HydrophobicContact CD1-CZ2 4.08Å; L170-W386 HydrophobicContact CD1-CZ3 3.88Å; L170-W386 HydrophobicContact CG-CH2 4.29Å; L170-L389 HydrophobicContact CD1-CD1 4.21Å; L170-R425 PolarHBondContact O-NH1 2.78Å; L170-R425 PolarHBondContact O-NH2 3.08Å; L170-L426 HydrophobicContact CD2-CD1 3.52Å; L170-L426 HydrophobicContact CD2-CD2 3.84Å; L170-L426 HydrophobicContact CD2-CG 4.31Å
171F94.3Very high87.2Confident33 Ų3351.9 Ų51.915%0.14531%0.311CS..THydrogen-bonded Turntrans-109.71.4175.4-75.9-77.4000114.8L4 F7 L155 I167 V169 D173 W386L4-F171 HydrophobicContact CD1-CD1 4.45Å; L4-F171 HydrophobicContact CD1-CD2 3.71Å; L4-F171 HydrophobicContact CD1-CE1 4.07Å; L4-F171 HydrophobicContact CD1-CE2 3.22Å; L4-F171 HydrophobicContact CD1-CG 4.31Å; L4-F171 HydrophobicContact CD1-CZ 3.44Å; L4-F171 VanDerWaalsContact CD1-CZ 3.44Å; F7-F171 HydrophobicContact CB-CE1 3.76Å; F7-F171 HydrophobicContact CB-CZ 4.46Å; F7-F171 AromaticContact CD1-CE1 3.64Å; F7-F171 HydrophobicContact CD1-CE1 3.64Å; F7-F171 AromaticContact CD1-CZ 3.51Å; F7-F171 HydrophobicContact CD1-CZ 3.51Å; F7-F171 HydrophobicContact CD2-CE1 4.17Å; F7-F171 HydrophobicContact CE1-CE1 4.3Å; F7-F171 AromaticContact CE1-CZ 3.86Å; F7-F171 HydrophobicContact CE1-CZ 3.86Å; F7-F171 AromaticContact CG-CE1 3.57Å; F7-F171 HydrophobicContact CG-CE1 3.57Å; F7-F171 AromaticContact CG-CZ 3.96Å; F7-F171 HydrophobicContact CG-CZ 3.96Å; L155-F171 HydrophobicContact CD1-CE2 4.45Å; L155-F171 HydrophobicContact CD2-CE2 4.43Å; L155-F171 HydrophobicContact CD2-CZ 4.34Å; I167-F171 HydrophobicContact CG2-CD2 3.92Å; I167-F171 HydrophobicContact CG2-CE2 4.27Å; I167-F171 WeakPolarHBondContact O-CD2 3.14Å; I167-F171 PolarHBondContact O-N 3.44Å; I167-F171 VanDerWaalsContact O-N 3.1Å; V169-F171 PolarHBondContact O-N 3.12Å; V169-F171 VanDerWaalsContact O-N 3.08Å; F171-D173 VanDerWaalsContact C-N 3.27Å; F171-D173 PolarHBondContact O-N 3.26Å; F171-W386 HydrophobicContact CD2-CH2 4.32Å; F171-W386 HydrophobicContact CD2-CZ2 4.29Å; F171-W386 AromaticContact CE2-CH2 3.58Å; F171-W386 HydrophobicContact CE2-CH2 3.58Å; F171-W386 AromaticContact CE2-CZ2 3.3Å; F171-W386 HydrophobicContact CE2-CZ2 3.3Å; F171-W386 HydrophobicContact CZ-CH2 4.37Å; F171-W386 AromaticContact CZ-CZ2 3.65Å; F171-W386 HydrophobicContact CZ-CZ2 3.65Å
172G90.1Very high85.9Confident41 Ų4156 Ų5642%0.42334%0.336SS..THydrogen-bonded Turntrans75.29.5-178.900000115.1H168 V169 A174H168-G172 PolarHBondContact O-N 3.12Å; V169-G172 PolarHBondContact O-N 2.69Å; V169-G172 VanDerWaalsContact O-N 3.14Å; G172-A174 PolarHBondContact O-N 2.81Å
173D89.6Confident84.8Confident83 Ų8359.7 Ų59.744%0.44435%0.354SS..SBendtrans-70.3-18.7170.4-78.8-9000110.8A1 H168 F171A1-D173 PolarHBondContact N-OD2 2.81Å; H168-D173 HydrophobicContact CB-CB 4.11Å; H168-D173 IonicContact ND1-OD2 3.01Å; H168-D173 PolarHBondContact O-N 2.8Å; F171-D173 VanDerWaalsContact C-N 3.27Å; F171-D173 PolarHBondContact O-N 3.26Å
174A90.1Very high83.9Confident39 Ų3969.1 Ų69.132%0.32240%0.398SS..SBendtrans-142.1159.7174.400000112.1H168 V169 G172 Y430H168-A174 HydrophobicContact CB-CB 3.85Å; H168-A174 PolarHBondContact O-N 3.28Å; H168-A174 VanDerWaalsContact O-N 3.1Å; V169-A174 HydrophobicContact CG2-CB 4.19Å; G172-A174 PolarHBondContact O-N 2.81Å; A174-Y430 PolarHBondContact O-OH 2.86Å; A174-Y430 VanDerWaalsContact O-OH 3.11Å
175Q91.3Very high83.5Confident143 Ų14369.9 Ų69.967%0.66840%0.397SS*.  trans-88.1145.1173.7-66.4-61.9-27.400111.2
176P90.7Very high83.4Confident27 Ų2773.8 Ų73.818%0.17541%0.407CS..  trans-63.5142.4174.928.4-35.3000110.6V169 Y430 V434V169-P176 HydrophobicContact CG1-CB 3.97Å; P176-Y430 VanDerWaalsContact CD-CE1 3.47Å; P176-Y430 HydrophobicContact CG-CD1 4.11Å; P176-Y430 HydrophobicContact CG-CE1 4.13Å; P176-V434 HydrophobicContact CB-CG1 3.73Å; P176-V434 HydrophobicContact CG-CG1 3.54Å
177S89.4Confident83.4Confident35 Ų3576.6 Ų76.625%0.24542%0.42CS..  trans-123.1150.7-177.976.70000112.9Q206 R207 E208S177-Q206 PolarHBondContact O-OE1 3.15Å; S177-R207 VanDerWaalsContact O-CB 3.29Å; S177-R207 WeakPolarHBondContact O-CB 3.4Å; S177-R207 PolarHBondContact O-N 2.92Å; S177-R207 WeakPolarHBondContact OG-CD 3.43Å; S177-E208 PolarHBondContact N-OE2 2.94Å; S177-E208 PolarHBondContact OG-OE1 3.36Å; S177-E208 PolarHBondContact OG-OE2 3.14Å
178S83.4Confident83.3Confident65 Ų6581.3 Ų81.346%0.45544%0.44SS..BIsolated β-bridgetrans-113.9159.117958.20000111.9
179H77.3Confident83.2Confident89 Ų8979.6 Ų79.641%0.41243%0.433SS..  trans-76.6133.7169.2-64.388.4000110.1Q181 S205 R207H179-Q181 PolarHBondContact O-N 2.93Å; H179-S205 PolarHBondContact N-O 2.81Å; H179-S205 PolarHBondContact ND1-O 3.32Å; H179-R207 WeakPolarHBondContact CE1-CG 3.35Å
180S59.8Low82.9Confident120 Ų12084.1 Ų84.184%0.83947%0.465SS*.SBendtrans-72.5-11.4-177.4-38.80000114.5
181Q59.3Low82.8Confident152 Ų15291.9 Ų91.971%0.7150%0.501SS*.SBendtrans-110.9121.4-178.6-72.7-179.7-24.500110.1H179 N183H179-Q181 PolarHBondContact O-N 2.93Å; Q181-N183 PolarHBondContact O-N 3.16Å
182S56.9Low82.8Confident117 Ų11790.4 Ų90.482%0.81850%0.495SS*.  trans-72.597.3161.450.80000108.2E184S182-E184 PolarHBondContact O-N 3.26Å
183N61.1Low83.1Confident106 Ų10689.2 Ų89.257%0.56748%0.479SS*.  trans-65.3122.6166-69.6-15000107.2Q181 F185Q181-N183 PolarHBondContact O-N 3.16Å; N183-F185 WeakPolarHBondContact O-CD1 3.4Å; N183-F185 PolarHBondContact O-N 2.77Å
184E72.3Confident83.5Confident200 Ų20090.9 Ų90.994%0.93549%0.488SS*.  trans-65.7128.8166.6-68.5-17615900108.5S182S182-E184 PolarHBondContact O-N 3.26Å
185F84.2Confident83.8Confident50 Ų5089.7 Ų89.722%0.21948%0.477CS..  trans-140.9140.6176.566.1-89.2000110.3N183 F187 V200 L204 Q230N183-F185 WeakPolarHBondContact O-CD1 3.4Å; N183-F185 PolarHBondContact O-N 2.77Å; F185-F187 AromaticContact CE2-CD1 3.88Å; F185-F187 HydrophobicContact CE2-CD1 3.88Å; F185-F187 AromaticContact CE2-CE1 3.54Å; F185-F187 HydrophobicContact CE2-CE1 3.54Å; F185-F187 HydrophobicContact CE2-CE2 4.37Å; F185-F187 HydrophobicContact CE2-CG 4.43Å; F185-F187 AromaticContact CE2-CZ 3.81Å; F185-F187 HydrophobicContact CE2-CZ 3.81Å; F185-F187 AromaticContact CZ-CE1 3.98Å; F185-F187 HydrophobicContact CZ-CE1 3.98Å; F185-F187 AromaticContact CZ-CZ 3.99Å; F185-F187 HydrophobicContact CZ-CZ 3.99Å; F185-V200 HydrophobicContact CE2-CG1 3.91Å; F185-V200 HydrophobicContact CZ-CG1 4.03Å; F185-L204 HydrophobicContact CD1-CD1 3.91Å; F185-L204 HydrophobicContact CD2-CD1 4.11Å; F185-L204 HydrophobicContact CE1-CD1 3.62Å; F185-L204 HydrophobicContact CE2-CD1 3.81Å; F185-L204 HydrophobicContact CG-CD1 4.19Å; F185-L204 HydrophobicContact CZ-CD1 3.57Å; F185-Q230 HydrophobicContact CD2-CG 4.21Å; F185-Q230 HydrophobicContact CE2-CG 4.38Å
186E90.3Very high84.1Confident153 Ų15383.2 Ų83.272%0.71545%0.447SS*.  trans-83129172.1-61.7172.8150.900110.1Q230E186-Q230 PolarHBondContact O-NE2 2.81Å
187F93.3Very high84.4Confident60 Ų6085.6 Ų85.626%0.26345%0.452SS..  trans-64139.3171.8-61.9-84.5000111.2F185 L192 R197 V200 E226F185-F187 AromaticContact CE2-CD1 3.88Å; F185-F187 HydrophobicContact CE2-CD1 3.88Å; F185-F187 AromaticContact CE2-CE1 3.54Å; F185-F187 HydrophobicContact CE2-CE1 3.54Å; F185-F187 HydrophobicContact CE2-CE2 4.37Å; F185-F187 HydrophobicContact CE2-CG 4.43Å; F185-F187 AromaticContact CE2-CZ 3.81Å; F185-F187 HydrophobicContact CE2-CZ 3.81Å; F185-F187 AromaticContact CZ-CE1 3.98Å; F185-F187 HydrophobicContact CZ-CE1 3.98Å; F185-F187 AromaticContact CZ-CZ 3.99Å; F185-F187 HydrophobicContact CZ-CZ 3.99Å; F187-L192 HydrophobicContact CD1-CD1 3.8Å; F187-L192 HydrophobicContact CE1-CD1 4.44Å; F187-L192 HydrophobicContact CG-CD1 4.41Å; F187-R197 HydrophobicContact CD1-CG 4.49Å; F187-R197 HydrophobicContact CD2-CG 4.46Å; F187-R197 HydrophobicContact CE1-CB 4.11Å; F187-R197 HydrophobicContact CE1-CG 3.98Å; F187-R197 HydrophobicContact CE2-CB 4.34Å; F187-R197 HydrophobicContact CE2-CG 3.97Å; F187-R197 HydrophobicContact CZ-CB 3.71Å; F187-R197 HydrophobicContact CZ-CG 3.71Å; F187-V200 HydrophobicContact CD1-CG1 4.31Å; F187-V200 HydrophobicContact CE1-CB 3.98Å; F187-V200 HydrophobicContact CE1-CG1 3.85Å; F187-V200 HydrophobicContact CE1-CG2 4.49Å; F187-E226 WeakPolarHBondContact CA-OE1 3.43Å; F187-E226 HydrophobicContact CD1-CG 4.19Å
188F92.6Very high84.7Confident111 Ų11188.7 Ų88.749%0.48746%0.463SS..SBendtrans-72.9-37.1171.9-70.7-88.4000111.4E226 L229 Q230 K233F188-E226 PolarHBondContact N-OE1 2.99Å; F188-E226 PolarHBondContact N-OE2 3.24Å; F188-L229 HydrophobicContact CB-CD1 4.23Å; F188-L229 HydrophobicContact CD2-CB 3.62Å; F188-L229 HydrophobicContact CD2-CD1 4.43Å; F188-L229 HydrophobicContact CE2-CB 3.72Å; F188-L229 HydrophobicContact CG-CB 4.27Å; F188-L229 HydrophobicContact CG-CD1 4.32Å; F188-L229 HydrophobicContact CZ-CB 4.43Å; F188-Q230 HydrophobicContact CD2-CG 4.41Å; F188-Q230 HydrophobicContact CE2-CG 4.44Å; F188-K233 HydrophobicContact CE2-CB 4.12Å; F188-K233 HydrophobicContact CE2-CD 3.85Å; F188-K233 HydrophobicContact CE2-CG 4.46Å; F188-K233 HydrophobicContact CZ-CB 3.96Å; F188-K233 HydrophobicContact CZ-CD 3.7Å; F188-K233 HydrophobicContact CZ-CG 4.06Å
189N91.2Very high85.3Confident44 Ų4485.7 Ų85.724%0.23544%0.442CS..  trans-97.9113.3170.4-175.217.8000111.4E191 L192 E226N189-E191 VanDerWaalsContact C-N 3.33Å; N189-E191 WeakPolarHBondContact OD1-CB 3.24Å; N189-E191 PolarHBondContact OD1-N 2.87Å; N189-L192 HydrophobicContact CB-CD1 4.31Å; N189-L192 HydrophobicContact CB-CD2 4.24Å; N189-L192 HydrophobicContact CB-CG 3.96Å; N189-L192 WeakPolarHBondContact ND2-CD2 3.46Å; N189-L192 WeakPolarHBondContact O-CG 3.46Å; N189-E226 PolarHBondContact N-OE2 2.89Å
190S89.9Confident86.2Confident98 Ų9881.4 Ų81.469%0.68542%0.422SS*.THydrogen-bonded Turntrans-71.4-25.8174.148.70000113.4L192 R197S190-L192 VanDerWaalsContact C-N 3.28Å; S190-L192 PolarHBondContact O-N 2.81Å; S190-R197 PolarHBondContact O-NH1 2.83Å
191E92.3Very high87.9Confident163 Ų16377.9 Ų77.976%0.76240%0.397SS*.THydrogen-bonded Turntrans-82.15.7-173.4-55.4-175.3159.700114.6N189N189-E191 VanDerWaalsContact C-N 3.33Å; N189-E191 WeakPolarHBondContact OD1-CB 3.24Å; N189-E191 PolarHBondContact OD1-N 2.87Å
192L94.8Very high89.6Confident3 Ų371.8 Ų71.82%0.01637%0.369CS..  trans-62.4144.6174.2-61.2172.5000110.5F187 N189 S190 Q196 R197 T222 E226F187-L192 HydrophobicContact CD1-CD1 3.8Å; F187-L192 HydrophobicContact CE1-CD1 4.44Å; F187-L192 HydrophobicContact CG-CD1 4.41Å; N189-L192 HydrophobicContact CB-CD1 4.31Å; N189-L192 HydrophobicContact CB-CD2 4.24Å; N189-L192 HydrophobicContact CB-CG 3.96Å; N189-L192 WeakPolarHBondContact ND2-CD2 3.46Å; N189-L192 WeakPolarHBondContact O-CG 3.46Å; S190-L192 VanDerWaalsContact C-N 3.28Å; S190-L192 PolarHBondContact O-N 2.81Å; L192-Q196 HydrophobicContact CB-CB 4.08Å; L192-Q196 HydrophobicContact CD2-CB 4.22Å; L192-R197 HydrophobicContact CB-CG 4.07Å; L192-R197 PolarHBondContact O-NH1 3.01Å; L192-R197 PolarHBondContact O-NH2 3.03Å; L192-T222 HydrophobicContact CD2-CG2 3.94Å; L192-E226 HydrophobicContact CD1-CB 4.23Å; L192-E226 HydrophobicContact CD1-CG 3.78Å
193D96.3Very high91.4Very high16 Ų1666.2 Ų66.29%0.08633%0.33CS..  trans-80.1171166.765.177.1000112.1S195 Q196 R197 V440 Y442D193-S195 VanDerWaalsContact C-N 3.32Å; D193-S195 PolarHBondContact O-N 2.86Å; D193-S195 WeakPolarHBondContact OD1-CA 3.49Å; D193-S195 VanDerWaalsContact OD1-CB 3.3Å; D193-S195 WeakPolarHBondContact OD1-CB 3.3Å; D193-S195 PolarHBondContact OD1-N 2.79Å; D193-S195 PolarHBondContact OD1-OG 3.42Å; D193-Q196 WeakPolarHBondContact O-CB 3.34Å; D193-Q196 PolarHBondContact O-N 3.02Å; D193-Q196 VanDerWaalsContact O-N 3.12Å; D193-Q196 PolarHBondContact OD1-N 2.83Å; D193-Q196 VanDerWaalsContact OD2-CG 3.23Å; D193-Q196 WeakPolarHBondContact OD2-CG 3.13Å; D193-Q196 PolarHBondContact OD2-NE2 3.39Å; D193-Q196 PolarHBondContact OD2-OE1 2.84Å; D193-R197 WeakPolarHBondContact O-CG 3.33Å; D193-R197 PolarHBondContact O-N 3.45Å; D193-V440 HydrophobicContact CB-CB 4.28Å; D193-V440 HydrophobicContact CB-CG2 4.04Å; D193-Y442 WeakPolarHBondContact CB-OH 3.39Å; D193-Y442 PolarHBondContact OD2-OH 3.31Å; D193-Y442 VanDerWaalsContact OD2-OH 3.11Å
194D96.3Very high93Very high118 Ų11862 Ų6263%0.63131%0.307SS*.Hα-helixtrans-68.1-30.2-174-56.4-34000112.8Q196 R197 E198D194-Q196 VanDerWaalsContact C-N 3.33Å; D194-R197 PolarHBondContact O-N 2.83Å; D194-R197 IonicContact OD1-CZ 3.31Å; D194-R197 IonicContact OD1-NE 2.69Å; D194-R197 PolarHBondContact OD1-NE 3.17Å; D194-R197 IonicContact OD1-NH2 3.59Å; D194-E198 WeakPolarHBondContact O-CB 3.47Å; D194-E198 PolarHBondContact O-N 3.23Å
195S96.9Very high94Very high13 Ų1354.3 Ų54.39%0.09128%0.275CS..Hα-helixtrans-68.6-34.9173.2800000111.6D193 A199 L438 T439D193-S195 VanDerWaalsContact C-N 3.32Å; D193-S195 PolarHBondContact O-N 2.86Å; D193-S195 WeakPolarHBondContact OD1-CA 3.49Å; D193-S195 VanDerWaalsContact OD1-CB 3.3Å; D193-S195 WeakPolarHBondContact OD1-CB 3.3Å; D193-S195 PolarHBondContact OD1-N 2.79Å; D193-S195 PolarHBondContact OD1-OG 3.42Å; S195-A199 VanDerWaalsContact O-CB 3.26Å; S195-A199 WeakPolarHBondContact O-CB 3.32Å; S195-A199 PolarHBondContact O-N 3.1Å; S195-L438 WeakPolarHBondContact O-CD2 3.24Å; S195-T439 WeakPolarHBondContact CB-OG1 3.41Å; S195-T439 PolarHBondContact OG-N 3.13Å; S195-T439 VanDerWaalsContact OG-N 3.13Å
196Q97.8Very high94.4Very high7 Ų752.5 Ų52.53%0.03327%0.267CS..Hα-helixtrans-70.5-43.3172.3-64.8172.91.300111.6L192 D193 D194 A199 V200 T218 T223 L438L192-Q196 HydrophobicContact CB-CB 4.08Å; L192-Q196 HydrophobicContact CD2-CB 4.22Å; D193-Q196 WeakPolarHBondContact O-CB 3.34Å; D193-Q196 PolarHBondContact O-N 3.02Å; D193-Q196 VanDerWaalsContact O-N 3.12Å; D193-Q196 PolarHBondContact OD1-N 2.83Å; D193-Q196 VanDerWaalsContact OD2-CG 3.23Å; D193-Q196 WeakPolarHBondContact OD2-CG 3.13Å; D193-Q196 PolarHBondContact OD2-NE2 3.39Å; D193-Q196 PolarHBondContact OD2-OE1 2.84Å; D194-Q196 VanDerWaalsContact C-N 3.33Å; Q196-A199 PolarHBondContact O-N 3.04Å; Q196-V200 VanDerWaalsContact O-CG2 3.23Å; Q196-V200 WeakPolarHBondContact O-CG2 3.5Å; Q196-V200 PolarHBondContact O-N 3.02Å; Q196-T218 PolarHBondContact NE2-O 3.45Å; Q196-T223 HydrophobicContact CB-CG2 4.29Å; Q196-L438 HydrophobicContact CB-CD2 4.43Å; Q196-L438 HydrophobicContact CG-CD1 4.42Å; Q196-L438 HydrophobicContact CG-CD2 3.95Å
197R96.3Very high94.5Very high77 Ų7750.7 Ų50.729%0.29125%0.254SS..Hα-helixtrans-62-41.9175.8-72.3-169.6-113.7-882.1112.1F187 S190 L192 D193 D194 S201F187-R197 HydrophobicContact CD1-CG 4.49Å; F187-R197 HydrophobicContact CD2-CG 4.46Å; F187-R197 HydrophobicContact CE1-CB 4.11Å; F187-R197 HydrophobicContact CE1-CG 3.98Å; F187-R197 HydrophobicContact CE2-CB 4.34Å; F187-R197 HydrophobicContact CE2-CG 3.97Å; F187-R197 HydrophobicContact CZ-CB 3.71Å; F187-R197 HydrophobicContact CZ-CG 3.71Å; S190-R197 PolarHBondContact O-NH1 2.83Å; L192-R197 HydrophobicContact CB-CG 4.07Å; L192-R197 PolarHBondContact O-NH1 3.01Å; L192-R197 PolarHBondContact O-NH2 3.03Å; D193-R197 WeakPolarHBondContact O-CG 3.33Å; D193-R197 PolarHBondContact O-N 3.45Å; D194-R197 PolarHBondContact O-N 2.83Å; D194-R197 IonicContact OD1-CZ 3.31Å; D194-R197 IonicContact OD1-NE 2.69Å; D194-R197 PolarHBondContact OD1-NE 3.17Å; D194-R197 IonicContact OD1-NH2 3.59Å; R197-S201 WeakPolarHBondContact O-CB 3.23Å; R197-S201 PolarHBondContact O-N 3.13Å; R197-S201 PolarHBondContact O-OG 3.01Å
198E95.4Very high94.6Very high101 Ų10149.1 Ų49.147%0.47225%0.248SC..Hα-helixtrans-63.5-49.4174.6-165.2-160.8166.600110.5D194 V200 S201 F202 R436D194-E198 WeakPolarHBondContact O-CB 3.47Å; D194-E198 PolarHBondContact O-N 3.23Å; E198-V200 VanDerWaalsContact C-N 3.31Å; E198-V200 PolarHBondContact O-N 3.18Å; E198-S201 PolarHBondContact O-N 3.43Å; E198-F202 WeakPolarHBondContact O-CB 3Å; E198-F202 PolarHBondContact O-N 3.2Å; E198-R436 WeakPolarHBondContact OE1-CD 3.36Å; E198-R436 IonicContact OE1-CZ 3.77Å; E198-R436 IonicContact OE1-NE 2.78Å; E198-R436 PolarHBondContact OE1-NE 3.32Å; E198-R436 IonicContact OE1-NH2 3.18Å
199A97.1Very high94.8Very high1 Ų143.9 Ų43.91%0.00822%0.224CC..Hα-helixtrans-59.8-38179.200000112.9S195 Q196 A203 V212 T223 R436 L438S195-A199 VanDerWaalsContact O-CB 3.26Å; S195-A199 WeakPolarHBondContact O-CB 3.32Å; S195-A199 PolarHBondContact O-N 3.1Å; Q196-A199 PolarHBondContact O-N 3.04Å; A199-A203 WeakPolarHBondContact O-CB 3.33Å; A199-A203 PolarHBondContact O-N 3.5Å; A199-V212 HydrophobicContact CB-CG1 4.49Å; A199-T223 HydrophobicContact CB-CG2 3.97Å; A199-R436 HydrophobicContact CB-CB 3.96Å; A199-L438 HydrophobicContact CB-CD2 3.71Å
200V96.7Very high95.1Very high0 Ų041.8 Ų41.80%021%0.213CC..Hα-helixtrans-63.6-55.8172172.90000110.1F185 F187 Q196 E198 F202 A203 L204 T223 E226 I227F185-V200 HydrophobicContact CE2-CG1 3.91Å; F185-V200 HydrophobicContact CZ-CG1 4.03Å; F187-V200 HydrophobicContact CD1-CG1 4.31Å; F187-V200 HydrophobicContact CE1-CB 3.98Å; F187-V200 HydrophobicContact CE1-CG1 3.85Å; F187-V200 HydrophobicContact CE1-CG2 4.49Å; Q196-V200 VanDerWaalsContact O-CG2 3.23Å; Q196-V200 WeakPolarHBondContact O-CG2 3.5Å; Q196-V200 PolarHBondContact O-N 3.02Å; E198-V200 VanDerWaalsContact C-N 3.31Å; E198-V200 PolarHBondContact O-N 3.18Å; V200-F202 VanDerWaalsContact C-N 3.28Å; V200-F202 PolarHBondContact O-N 3.43Å; V200-A203 PolarHBondContact O-N 3.31Å; V200-L204 HydrophobicContact CG1-CD1 4.14Å; V200-L204 HydrophobicContact CG1-CG 4.35Å; V200-L204 WeakPolarHBondContact O-CG 3.42Å; V200-L204 PolarHBondContact O-N 3.06Å; V200-T223 HydrophobicContact CG2-CG2 3.85Å; V200-E226 HydrophobicContact CG1-CG 4.01Å; V200-E226 HydrophobicContact CG2-CB 4Å; V200-E226 HydrophobicContact CG2-CG 3.75Å; V200-I227 HydrophobicContact CB-CG1 4.26Å; V200-I227 HydrophobicContact CG1-CG1 4.32Å; V200-I227 HydrophobicContact CG2-CG1 3.97Å
201S94.7Very high95.5Very high46 Ų4637.1 Ų37.132%0.32218%0.181SC..Hα-helixtrans-56.3-43.4-176.9-53.80000112.1R197 E198 L204 S205R197-S201 WeakPolarHBondContact O-CB 3.23Å; R197-S201 PolarHBondContact O-N 3.13Å; R197-S201 PolarHBondContact O-OG 3.01Å; E198-S201 PolarHBondContact O-N 3.43Å; S201-L204 PolarHBondContact O-N 3.19Å; S201-S205 PolarHBondContact O-N 3.01Å; S201-S205 VanDerWaalsContact O-N 3.08Å
202F95.1Very high95.8Very high24 Ų2429.5 Ų29.511%0.10515%0.145CC..Hα-helixtrans-63.7-49.1173.9-179.2-90.5000112.1E198 V200 L204 S205 Q206 A210 S433 V434 R436E198-F202 WeakPolarHBondContact O-CB 3Å; E198-F202 PolarHBondContact O-N 3.2Å; V200-F202 VanDerWaalsContact C-N 3.28Å; V200-F202 PolarHBondContact O-N 3.43Å; F202-L204 PolarHBondContact O-N 3.23Å; F202-S205 PolarHBondContact O-N 3.29Å; F202-S205 VanDerWaalsContact O-N 3.13Å; F202-S205 PolarHBondContact O-OG 2.7Å; F202-S205 VanDerWaalsContact O-OG 3.06Å; F202-Q206 HydrophobicContact CD1-CG 4.19Å; F202-Q206 HydrophobicContact CE1-CG 3.77Å; F202-Q206 HydrophobicContact CZ-CG 3.98Å; F202-Q206 WeakPolarHBondContact O-CG 3.35Å; F202-Q206 PolarHBondContact O-N 3.48Å; F202-Q206 VanDerWaalsContact O-N 3.13Å; F202-A210 HydrophobicContact CE1-CB 4.38Å; F202-S433 WeakPolarHBondContact CZ-O 3.31Å; F202-V434 WeakPolarHBondContact CE1-O 3.39Å; F202-R436 HydrophobicContact CB-CG 3.89Å; F202-R436 HydrophobicContact CD1-CG 3.7Å; F202-R436 HydrophobicContact CD2-CG 4.15Å; F202-R436 HydrophobicContact CE1-CG 4.27Å; F202-R436 HydrophobicContact CG-CG 3.64Å
203A95.8Very high95.9Very high0 Ų029.6 Ų29.60%015%0.146CC..Hα-helixtrans-63.2-30.8179.800000112.8A199 V200 A210 I227 K394 I396A199-A203 WeakPolarHBondContact O-CB 3.33Å; A199-A203 PolarHBondContact O-N 3.5Å; V200-A203 PolarHBondContact O-N 3.31Å; A203-A210 HydrophobicContact CB-CB 4Å; A203-I227 HydrophobicContact CB-CD1 3.59Å; A203-I227 HydrophobicContact CB-CG1 4.01Å; A203-I227 HydrophobicContact CB-CG2 4.37Å; A203-K394 VanDerWaalsContact O-CE 3.27Å; A203-K394 WeakPolarHBondContact O-CE 3.22Å; A203-K394 PolarHBondContact O-NZ 3.45Å; A203-I396 HydrophobicContact CB-CD1 4.36Å
204L94.1Very high96Very high16 Ų1628.9 Ų28.98%0.08414%0.142CC..Hα-helixtrans-71.4-42.1172.5-60.7-177.1000111.8F185 V200 S201 F202 Q206 Q230 W371 K394F185-L204 HydrophobicContact CD1-CD1 3.91Å; F185-L204 HydrophobicContact CD2-CD1 4.11Å; F185-L204 HydrophobicContact CE1-CD1 3.62Å; F185-L204 HydrophobicContact CE2-CD1 3.81Å; F185-L204 HydrophobicContact CG-CD1 4.19Å; F185-L204 HydrophobicContact CZ-CD1 3.57Å; V200-L204 HydrophobicContact CG1-CD1 4.14Å; V200-L204 HydrophobicContact CG1-CG 4.35Å; V200-L204 WeakPolarHBondContact O-CG 3.42Å; V200-L204 PolarHBondContact O-N 3.06Å; S201-L204 PolarHBondContact O-N 3.19Å; F202-L204 PolarHBondContact O-N 3.23Å; L204-Q206 PolarHBondContact O-N 3.32Å; L204-Q230 HydrophobicContact CD1-CB 3.77Å; L204-Q230 HydrophobicContact CD1-CG 4.08Å; L204-Q230 HydrophobicContact CD2-CB 3.81Å; L204-Q230 HydrophobicContact CG-CB 4.43Å; L204-W371 HydrophobicContact CD2-CH2 3.52Å; L204-W371 HydrophobicContact CD2-CZ3 3.85Å; L204-K394 PolarHBondContact O-NZ 3.29Å; L204-K394 VanDerWaalsContact O-NZ 3.1Å
205S92.9Very high96Very high39 Ų3923.4 Ų23.427%0.27311%0.113SC..Hα-helixtrans-71.7-27.5-176.374.20000114.5H179 S201 F202H179-S205 PolarHBondContact N-O 2.81Å; H179-S205 PolarHBondContact ND1-O 3.32Å; S201-S205 PolarHBondContact O-N 3.01Å; S201-S205 VanDerWaalsContact O-N 3.08Å; F202-S205 PolarHBondContact O-N 3.29Å; F202-S205 VanDerWaalsContact O-N 3.13Å; F202-S205 PolarHBondContact O-OG 2.7Å; F202-S205 VanDerWaalsContact O-OG 3.06Å
206Q93.6Very high95.9Very high12 Ų1223 Ų236%0.05611%0.11CC..BIsolated β-bridgetrans-63145.9176-66.6-58-26.800113S177 F202 L204 L209 A210 K394S177-Q206 PolarHBondContact O-OE1 3.15Å; F202-Q206 HydrophobicContact CD1-CG 4.19Å; F202-Q206 HydrophobicContact CE1-CG 3.77Å; F202-Q206 HydrophobicContact CZ-CG 3.98Å; F202-Q206 WeakPolarHBondContact O-CG 3.35Å; F202-Q206 PolarHBondContact O-N 3.48Å; F202-Q206 VanDerWaalsContact O-N 3.13Å; L204-Q206 PolarHBondContact O-N 3.32Å; Q206-L209 WeakPolarHBondContact CB-O 3.08Å; Q206-L209 WeakPolarHBondContact CG-O 3.1Å; Q206-A210 HydrophobicContact CB-CB 4.16Å; Q206-A210 HydrophobicContact CG-CB 4.05Å; Q206-K394 WeakPolarHBondContact O-CE 3.25Å; Q206-K394 PolarHBondContact O-NZ 2.9Å
207R92.4Very high95.7Very high116 Ų11623.4 Ų23.444%0.43812%0.116SC..SBendtrans-90.2-55176.8-75.7168.6164.4-174.54.2112.5S177 H179 K394S177-R207 VanDerWaalsContact O-CB 3.29Å; S177-R207 WeakPolarHBondContact O-CB 3.4Å; S177-R207 PolarHBondContact O-N 2.92Å; S177-R207 WeakPolarHBondContact OG-CD 3.43Å; H179-R207 WeakPolarHBondContact CE1-CG 3.35Å; R207-K394 VanDerWaalsContact O-CB 3.3Å; R207-K394 WeakPolarHBondContact O-CB 3.3Å; R207-K394 WeakPolarHBondContact O-CD 3.44Å; R207-K394 VanDerWaalsContact O-CG 3.27Å; R207-K394 WeakPolarHBondContact O-CG 3.22Å
208E94.9Very high95.7Very high27 Ų2719.8 Ų19.813%0.12610%0.103CC..SBendtrans-97.7-52.1-175.6-57.378.6-163.900112.8L166 V169 S177 K394 C395L166-E208 HydrophobicContact CD1-CB 4.27Å; L166-E208 WeakPolarHBondContact CD1-O 3.43Å; V169-E208 HydrophobicContact CB-CB 4.35Å; V169-E208 HydrophobicContact CG2-CB 4.05Å; V169-E208 HydrophobicContact CG2-CG 3.91Å; S177-E208 PolarHBondContact N-OE2 2.94Å; S177-E208 PolarHBondContact OG-OE1 3.36Å; S177-E208 PolarHBondContact OG-OE2 3.14Å; E208-K394 CarbonylContact O-C 3.6Å; E208-K394 WeakPolarHBondContact O-CA 3.41Å; E208-C395 PolarHBondContact O-N 3.28Å
209L96.6Very high95.6Very high0 Ų015.9 Ų15.90%09%0.09CC..EExtended strand (participates in β ladder)trans-135.4130.4-166.7172.663.5000111.9V169 L170 Q206 V211 C395 L397 L426 Y430 V434V169-L209 HydrophobicContact CG1-CB 4.31Å; V169-L209 HydrophobicContact CG1-CD2 4.36Å; L170-L209 HydrophobicContact CD2-CD1 4.25Å; L170-L209 HydrophobicContact CD2-CD2 4.19Å; Q206-L209 WeakPolarHBondContact CB-O 3.08Å; Q206-L209 WeakPolarHBondContact CG-O 3.1Å; L209-V211 HydrophobicContact CD1-CG2 3.98Å; L209-V211 HydrophobicContact CG-CG2 4.34Å; L209-C395 VanDerWaalsContact CD1-SG 3.58Å; L209-L397 HydrophobicContact CD1-CD1 4.09Å; L209-L397 HydrophobicContact CD1-CG 4.2Å; L209-L426 HydrophobicContact CD1-CD1 4.18Å; L209-L426 HydrophobicContact CD2-CD1 4.06Å; L209-L426 HydrophobicContact CD2-CD2 4.13Å; L209-L426 HydrophobicContact CD2-CG 4.49Å; L209-Y430 HydrophobicContact CD2-CD2 4.44Å; L209-V434 HydrophobicContact CD2-CB 4.23Å; L209-V434 HydrophobicContact CD2-CG1 4.1Å; L209-V434 HydrophobicContact CD2-CG2 4.21Å; L209-V434 HydrophobicContact CG-CB 4.27Å; L209-V434 HydrophobicContact CG-CG1 4.37Å
210A97.6Very high95.5Very high0 Ų016.7 Ų16.70%09%0.093CC..EExtended strand (participates in β ladder)trans-130.8144.8162.400000110.9F202 A203 Q206 C395 I396 L397F202-A210 HydrophobicContact CE1-CB 4.38Å; A203-A210 HydrophobicContact CB-CB 4Å; Q206-A210 HydrophobicContact CB-CB 4.16Å; Q206-A210 HydrophobicContact CG-CB 4.05Å; A210-C395 PolarHBondContact N-O 3.28Å; A210-C395 VanDerWaalsContact N-O 3.09Å; A210-I396 HydrophobicContact CB-CG1 4.46Å; A210-I396 CarbonylContact O-C 3.55Å; A210-I396 WeakPolarHBondContact O-CA 3.36Å; A210-L397 PolarHBondContact O-N 3.24Å
211V98.3Very high95.3Very high1 Ų117.7 Ų17.71%0.00610%0.099CC..EExtended strand (participates in β ladder)trans-125.4118.3179-177.20000109.9L209 L397 M423 I427 V434 V435 R436L209-V211 HydrophobicContact CD1-CG2 3.98Å; L209-V211 HydrophobicContact CG-CG2 4.34Å; V211-L397 CarbonylContact C-O 3.56Å; V211-L397 VanDerWaalsContact CA-O 3.29Å; V211-L397 WeakPolarHBondContact CA-O 3.4Å; V211-L397 HydrophobicContact CG2-CB 4.37Å; V211-M423 HydrophobicContact CG1-CE 3.74Å; V211-M423 HydrophobicContact CG1-CG 4.05Å; V211-M423 HydrophobicContact CG1-SD 4.49Å; V211-I427 HydrophobicContact CG1-CD1 4.29Å; V211-I427 HydrophobicContact CG1-CG1 4.15Å; V211-V434 WeakPolarHBondContact CB-O 3.21Å; V211-V434 HydrophobicContact CG2-CG2 4.01Å; V211-V434 PolarHBondContact N-O 2.91Å; V211-V435 HydrophobicContact CB-CG2 4Å; V211-V435 HydrophobicContact CG1-CG2 4.15Å; V211-V435 CarbonylContact O-C 3.57Å; V211-V435 WeakPolarHBondContact O-CA 3.34Å; V211-R436 PolarHBondContact O-N 3.39Å
212V98.3Very high95.3Very high3 Ų317.5 Ų17.52%0.01810%0.096CC..EExtended strand (participates in β ladder)trans-99.5102.7173.5-177.30000108.5A199 G214 T223 I227 L397 A398 G399 L438A199-V212 HydrophobicContact CB-CG1 4.49Å; V212-G214 PolarHBondContact O-N 2.76Å; V212-T223 HydrophobicContact CG1-CG2 4.47Å; V212-I227 HydrophobicContact CG2-CD1 3.95Å; V212-L397 PolarHBondContact N-O 3.34Å; V212-A398 HydrophobicContact CB-CB 4.31Å; V212-A398 WeakPolarHBondContact O-CA 3.26Å; V212-G399 PolarHBondContact O-N 3.15Å; V212-L438 HydrophobicContact CG1-CD1 4.13Å; V212-L438 HydrophobicContact CG1-CD2 4.4Å; V212-L438 HydrophobicContact CG1-CG 4.17Å
213H97.9Very high95.4Very high5 Ų516.3 Ų16.32%0.0239%0.091CC..EExtended strand (participates in β ladder)trans-79.8110.8171-176.6-164.8000108.6P215 D400 Y401 M423 V435 R436 M437 L438H213-P215 VanDerWaalsContact O-CD 3.25Å; H213-P215 WeakPolarHBondContact O-CD 3.41Å; H213-D400 IonicContact CD2-OD1 3.79Å; H213-D400 IonicContact CE1-OD1 3.16Å; H213-D400 IonicContact NE2-OD1 2.85Å; H213-D400 PolarHBondContact NE2-OD1 3.08Å; H213-Y401 AromaticContact CE1-CD1 3.84Å; H213-Y401 AromaticContact CE1-CE1 3.41Å; H213-Y401 VanDerWaalsContact CE1-CE1 3.41Å; H213-Y401 WeakPolarHBondContact CE1-CE1 3.47Å; H213-Y401 AromaticContact ND1-CE1 3.71Å; H213-Y401 AromaticContact NE2-CD1 3.84Å; H213-Y401 AromaticContact NE2-CE1 3.9Å; H213-M423 HydrophobicContact CB-CE 4.22Å; H213-V435 HydrophobicContact CB-CG1 4Å; H213-R436 PolarHBondContact N-O 2.67Å; H213-M437 HydrophobicContact CB-CB 4.18Å; H213-M437 HydrophobicContact CB-CG 4.36Å; H213-M437 CarbonylContact O-C 3.42Å; H213-M437 VanDerWaalsContact O-CA 3.31Å; H213-M437 WeakPolarHBondContact O-CA 3.36Å; H213-L438 PolarHBondContact O-N 2.93Å
214G96.6Very high95.5Very high1 Ų116.4 Ų16.41%0.019%0.091CC..  trans-116.688.7-176.600000112.8V212 G399V212-G214 PolarHBondContact O-N 2.76Å; G214-G399 PolarHBondContact N-O 3.01Å
215P96.4Very high95.6Very high3 Ų316.1 Ų16.12%0.0199%0.09CC..  trans-54.6166.9173.9-24.531.9000114.3H213 G217 T218 M437 L438 Y457 L461H213-P215 VanDerWaalsContact O-CD 3.25Å; H213-P215 WeakPolarHBondContact O-CD 3.41Å; P215-G217 PolarHBondContact O-N 3.42Å; P215-T218 HydrophobicContact CB-CG2 3.77Å; P215-T218 HydrophobicContact CG-CG2 4.17Å; P215-T218 WeakPolarHBondContact O-CB 3.27Å; P215-T218 WeakPolarHBondContact O-CG2 3.47Å; P215-T218 PolarHBondContact O-N 2.96Å; P215-T218 VanDerWaalsContact O-N 3.17Å; P215-T218 PolarHBondContact O-OG1 3.12Å; P215-M437 HydrophobicContact CG-CE 3.62Å; P215-M437 HydrophobicContact CG-CG 4.09Å; P215-M437 HydrophobicContact CG-SD 4.48Å; P215-L438 WeakPolarHBondContact CD-O 3.37Å; P215-Y457 HydrophobicContact CB-CD1 4.03Å; P215-Y457 HydrophobicContact CB-CE1 3.79Å; P215-Y457 HydrophobicContact CG-CD1 3.92Å; P215-Y457 HydrophobicContact CG-CE1 4.01Å; P215-L461 HydrophobicContact CB-CD1 4.24Å; P215-L461 HydrophobicContact CB-CD2 3.64Å; P215-L461 HydrophobicContact CG-CD2 3.71Å
216P94.8Very high95.8Very high4 Ų414.5 Ų14.53%0.0268%0.078CC..THydrogen-bonded Turntrans-55.2126.7-177-25.834.8000113.2T218 Q403 M444 Y457 T602P216-T218 VanDerWaalsContact C-N 3.29Å; P216-T218 PolarHBondContact O-N 3.49Å; P216-Q403 HydrophobicContact CG-CG 4.46Å; P216-M444 HydrophobicContact CB-CE 4.27Å; P216-Y457 WeakPolarHBondContact CD-OH 3.14Å; P216-T602 HydrophobicContact CB-CG2 4.13Å; P216-T602 HydrophobicContact CG-CG2 3.91Å
217G93.8Very high96Very high16 Ų1613.9 Ų13.917%0.1658%0.076CC..THydrogen-bonded Turntrans79.3-2177.500000115.9P215 G219 Y442P215-G217 PolarHBondContact O-N 3.42Å; G217-G219 PolarHBondContact O-N 3.41Å; G217-G219 VanDerWaalsContact O-N 3.14Å; G217-Y442 PolarHBondContact O-N 2.75Å
218T96.2Very high96.2Very high1 Ų18.4 Ų8.41%0.0066%0.055CC..SBendtrans-789.6-174.160.20000116.2Q196 P215 P216 K220 L438 V440 Q441 L461Q196-T218 PolarHBondContact NE2-O 3.45Å; P215-T218 HydrophobicContact CB-CG2 3.77Å; P215-T218 HydrophobicContact CG-CG2 4.17Å; P215-T218 WeakPolarHBondContact O-CB 3.27Å; P215-T218 WeakPolarHBondContact O-CG2 3.47Å; P215-T218 PolarHBondContact O-N 2.96Å; P215-T218 VanDerWaalsContact O-N 3.17Å; P215-T218 PolarHBondContact O-OG1 3.12Å; P216-T218 VanDerWaalsContact C-N 3.29Å; P216-T218 PolarHBondContact O-N 3.49Å; T218-K220 VanDerWaalsContact C-N 3.32Å; T218-K220 PolarHBondContact O-N 3.44Å; T218-L438 HydrophobicContact CG2-CB 4.27Å; T218-L438 WeakPolarHBondContact O-CD1 3.44Å; T218-V440 VanDerWaalsContact CA-O 3.24Å; T218-V440 WeakPolarHBondContact CA-O 3.5Å; T218-Q441 HydrophobicContact CG2-CB 4.05Å; T218-L461 HydrophobicContact CG2-CD2 4.39Å
219G93.9Very high96.2Very high19 Ų197.7 Ų7.720%0.1965%0.052CC..  trans7315.2179.800000115.4G217 T221 T222 T223G217-G219 PolarHBondContact O-N 3.41Å; G217-G219 VanDerWaalsContact O-N 3.14Å; G219-T221 VanDerWaalsContact C-N 3.33Å; G219-T221 PolarHBondContact O-N 3.31Å; G219-T221 VanDerWaalsContact O-N 3.07Å; G219-T222 VanDerWaalsContact O-CA 3.25Å; G219-T222 WeakPolarHBondContact O-CA 3.28Å; G219-T222 WeakPolarHBondContact O-CB 3.27Å; G219-T222 PolarHBondContact O-N 3.25Å; G219-T222 PolarHBondContact O-OG1 3.4Å; G219-T223 PolarHBondContact O-N 3.12Å; G219-T223 VanDerWaalsContact O-N 3.13Å; G219-T223 PolarHBondContact O-OG1 2.65Å
220K94.9Very high96.2Very high17 Ų177.8 Ų7.87%0.0745%0.052CC..Hα-helixtrans-32.8-56.6177-174-17668.1-149.10115.5T218 T222 T223 V224 D375 E376 A398 L438T218-K220 VanDerWaalsContact C-N 3.32Å; T218-K220 PolarHBondContact O-N 3.44Å; K220-T222 PolarHBondContact O-N 2.69Å; K220-T223 WeakPolarHBondContact O-CB 3.28Å; K220-T223 PolarHBondContact O-N 2.99Å; K220-V224 WeakPolarHBondContact O-CG2 3.45Å; K220-V224 PolarHBondContact O-N 3.46Å; K220-D375 WeakPolarHBondContact CE-OD1 3.49Å; K220-E376 IonicContact NZ-OE1 2.69Å; K220-E376 PolarHBondContact NZ-OE1 3.17Å; K220-E376 IonicContact NZ-OE2 2.74Å; K220-E376 PolarHBondContact NZ-OE2 2.87Å; K220-A398 HydrophobicContact CD-CB 4.34Å; K220-A398 HydrophobicContact CG-CB 4.28Å; K220-L438 HydrophobicContact CB-CD1 4.34Å
221T92.4Very high96Very high22 Ų227.8 Ų7.814%0.1355%0.052CC..Hα-helixtrans-68.4-21.9-178.7-46.80000112.5G219 V225 L251 D375G219-T221 VanDerWaalsContact C-N 3.33Å; G219-T221 PolarHBondContact O-N 3.31Å; G219-T221 VanDerWaalsContact O-N 3.07Å; T221-V225 WeakPolarHBondContact O-CB 3.26Å; T221-V225 WeakPolarHBondContact O-CG2 3.47Å; T221-V225 PolarHBondContact O-N 3.3Å; T221-V225 VanDerWaalsContact O-N 3.15Å; T221-L251 HydrophobicContact CG2-CD2 3.63Å; T221-L251 HydrophobicContact CG2-CG 4.21Å; T221-D375 PolarHBondContact OG1-OD2 3.47Å
222T95Very high95.8Very high41 Ų419.3 Ų9.325%0.2526%0.061SC..Hα-helixtrans-69.9-49.5169.4-45.60000109.9L192 G219 K220 V224 V225 E226 R254L192-T222 HydrophobicContact CD2-CG2 3.94Å; G219-T222 VanDerWaalsContact O-CA 3.25Å; G219-T222 WeakPolarHBondContact O-CA 3.28Å; G219-T222 WeakPolarHBondContact O-CB 3.27Å; G219-T222 PolarHBondContact O-N 3.25Å; G219-T222 PolarHBondContact O-OG1 3.4Å; K220-T222 PolarHBondContact O-N 2.69Å; T222-V224 VanDerWaalsContact C-N 3.34Å; T222-V224 PolarHBondContact O-N 3.01Å; T222-V225 PolarHBondContact O-N 2.74Å; T222-E226 PolarHBondContact O-N 3.01Å; T222-R254 PolarHBondContact OG1-NH1 2.88Å
223T97.1Very high95.6Very high0 Ų014.6 Ų14.60%08%0.084CC..Hα-helixtrans-57.7-45.5175.5-380000111.7Q196 A199 V200 V212 G219 K220 V225 E226 I227 L438Q196-T223 HydrophobicContact CB-CG2 4.29Å; A199-T223 HydrophobicContact CB-CG2 3.97Å; V200-T223 HydrophobicContact CG2-CG2 3.85Å; V212-T223 HydrophobicContact CG1-CG2 4.47Å; G219-T223 PolarHBondContact O-N 3.12Å; G219-T223 VanDerWaalsContact O-N 3.13Å; G219-T223 PolarHBondContact O-OG1 2.65Å; K220-T223 WeakPolarHBondContact O-CB 3.28Å; K220-T223 PolarHBondContact O-N 2.99Å; T223-V225 VanDerWaalsContact C-N 3.34Å; T223-V225 PolarHBondContact O-N 2.72Å; T223-E226 PolarHBondContact O-N 3.01Å; T223-I227 HydrophobicContact CG2-CD1 4.34Å; T223-I227 VanDerWaalsContact O-CG1 3.31Å; T223-I227 WeakPolarHBondContact O-CG1 3.25Å; T223-I227 PolarHBondContact O-N 3.26Å; T223-L438 HydrophobicContact CG2-CD2 4.25Å; T223-L438 WeakPolarHBondContact OG1-CD1 3.14Å
224V97.3Very high95.3Very high1 Ų118 Ų181%0.00610%0.1CC..Hα-helixtrans-62.4-40.2177.7170.90000111.7K220 T222 I227 I228 L251 V373 A398K220-V224 WeakPolarHBondContact O-CG2 3.45Å; K220-V224 PolarHBondContact O-N 3.46Å; T222-V224 VanDerWaalsContact C-N 3.34Å; T222-V224 PolarHBondContact O-N 3.01Å; V224-I227 PolarHBondContact O-N 2.95Å; V224-I228 HydrophobicContact CG1-CD1 3.78Å; V224-I228 VanDerWaalsContact O-CD1 3.3Å; V224-I228 WeakPolarHBondContact O-CD1 3.37Å; V224-I228 WeakPolarHBondContact O-CG1 3.29Å; V224-I228 PolarHBondContact O-N 2.92Å; V224-L251 HydrophobicContact CG1-CD2 3.84Å; V224-V373 HydrophobicContact CG1-CG1 3.73Å; V224-A398 HydrophobicContact CG2-CB 3.38Å
225V96.9Very high95.1Very high11 Ų1120.9 Ų20.97%0.06713%0.13CC..Hα-helixtrans-64.7-44.5176.2165.10000111.2T221 T222 T223 I227 I228 L229 L251 R254 L255T221-V225 WeakPolarHBondContact O-CB 3.26Å; T221-V225 WeakPolarHBondContact O-CG2 3.47Å; T221-V225 PolarHBondContact O-N 3.3Å; T221-V225 VanDerWaalsContact O-N 3.15Å; T222-V225 PolarHBondContact O-N 2.74Å; T223-V225 VanDerWaalsContact C-N 3.34Å; T223-V225 PolarHBondContact O-N 2.72Å; V225-I227 PolarHBondContact O-N 2.88Å; V225-I228 PolarHBondContact O-N 2.86Å; V225-L229 HydrophobicContact CG1-CD1 3.96Å; V225-L229 HydrophobicContact CG1-CG 4.36Å; V225-L229 VanDerWaalsContact O-CG 3.3Å; V225-L229 WeakPolarHBondContact O-CG 3.34Å; V225-L229 PolarHBondContact O-N 3.28Å; V225-L251 HydrophobicContact CG2-CD2 4.08Å; V225-R254 HydrophobicContact CG1-CB 4.42Å; V225-R254 HydrophobicContact CG2-CB 3.71Å; V225-L255 HydrophobicContact CG1-CD2 4.01Å; V225-L255 HydrophobicContact CG1-CG 4.47Å; V225-L255 HydrophobicContact CG2-CD2 4.41Å; V225-L255 HydrophobicContact CG2-CG 4.24Å
226E96.8Very high95Very high4 Ų422.6 Ų22.62%0.01914%0.138CC..Hα-helixtrans-57.8-48.4174.7-177.467.1-14600111.4F187 F188 N189 L192 V200 T222 T223 I228 L229 Q230F187-E226 WeakPolarHBondContact CA-OE1 3.43Å; F187-E226 HydrophobicContact CD1-CG 4.19Å; F188-E226 PolarHBondContact N-OE1 2.99Å; F188-E226 PolarHBondContact N-OE2 3.24Å; N189-E226 PolarHBondContact N-OE2 2.89Å; L192-E226 HydrophobicContact CD1-CB 4.23Å; L192-E226 HydrophobicContact CD1-CG 3.78Å; V200-E226 HydrophobicContact CG1-CG 4.01Å; V200-E226 HydrophobicContact CG2-CB 4Å; V200-E226 HydrophobicContact CG2-CG 3.75Å; T222-E226 PolarHBondContact O-N 3.01Å; T223-E226 PolarHBondContact O-N 3.01Å; E226-I228 VanDerWaalsContact C-N 3.29Å; E226-I228 PolarHBondContact O-N 2.71Å; E226-L229 PolarHBondContact O-N 2.92Å; E226-L229 VanDerWaalsContact O-N 3.12Å; E226-Q230 HydrophobicContact CG-CG 4.47Å; E226-Q230 WeakPolarHBondContact O-CG 3.38Å; E226-Q230 PolarHBondContact O-N 2.7Å; E226-Q230 PolarHBondContact OE1-NE2 3.29Å
227I96.9Very high95.1Very high0 Ų024.5 Ų24.50%015%0.145CC..Hα-helixtrans-54.3-44.7176.5-71.3165.5000111.5V200 A203 V212 T223 V224 V225 A231 W371 I396V200-I227 HydrophobicContact CB-CG1 4.26Å; V200-I227 HydrophobicContact CG1-CG1 4.32Å; V200-I227 HydrophobicContact CG2-CG1 3.97Å; A203-I227 HydrophobicContact CB-CD1 3.59Å; A203-I227 HydrophobicContact CB-CG1 4.01Å; A203-I227 HydrophobicContact CB-CG2 4.37Å; V212-I227 HydrophobicContact CG2-CD1 3.95Å; T223-I227 HydrophobicContact CG2-CD1 4.34Å; T223-I227 VanDerWaalsContact O-CG1 3.31Å; T223-I227 WeakPolarHBondContact O-CG1 3.25Å; T223-I227 PolarHBondContact O-N 3.26Å; V224-I227 PolarHBondContact O-N 2.95Å; V225-I227 PolarHBondContact O-N 2.88Å; I227-A231 PolarHBondContact O-N 2.86Å; I227-W371 HydrophobicContact CG2-CZ3 4.17Å; I227-I396 HydrophobicContact CG2-CD1 3.38Å
228I97.3Very high95.3Very high0 Ų023.8 Ų23.80%014%0.138CC..Hα-helixtrans-66.4-43.2178.6-66158.2000110.9V224 V225 E226 Q230 A231 V232 V238 C240 L255 V347 V373V224-I228 HydrophobicContact CG1-CD1 3.78Å; V224-I228 VanDerWaalsContact O-CD1 3.3Å; V224-I228 WeakPolarHBondContact O-CD1 3.37Å; V224-I228 WeakPolarHBondContact O-CG1 3.29Å; V224-I228 PolarHBondContact O-N 2.92Å; V225-I228 PolarHBondContact O-N 2.86Å; E226-I228 VanDerWaalsContact C-N 3.29Å; E226-I228 PolarHBondContact O-N 2.71Å; I228-Q230 VanDerWaalsContact C-N 3.35Å; I228-Q230 PolarHBondContact O-N 3.46Å; I228-A231 WeakPolarHBondContact O-CB 3.5Å; I228-A231 PolarHBondContact O-N 3.38Å; I228-V232 HydrophobicContact CG2-CG2 4.48Å; I228-V232 WeakPolarHBondContact O-CG2 3.25Å; I228-V232 PolarHBondContact O-N 2.69Å; I228-V238 HydrophobicContact CG1-CG1 4.45Å; I228-V238 HydrophobicContact CG2-CG1 4.45Å; I228-C240 WeakPolarHBondContact CD1-SG 3.01Å; I228-L255 HydrophobicContact CB-CD2 4.07Å; I228-L255 HydrophobicContact CD1-CD1 4.27Å; I228-L255 HydrophobicContact CG2-CD1 4.33Å; I228-L255 HydrophobicContact CG2-CD2 3.69Å; I228-V347 HydrophobicContact CG2-CG1 4.09Å; I228-V347 HydrophobicContact CG2-CG2 3.61Å; I228-V373 HydrophobicContact CD1-CG1 4.38Å; I228-V373 HydrophobicContact CG1-CG2 4.05Å
229L96.1Very high95.3Very high13 Ų1323.7 Ų23.77%0.06814%0.137CC..Hα-helixtrans-63.8-40179-68172.3000111.9F188 V225 E226 V232 K233 L255 C258 A260F188-L229 HydrophobicContact CB-CD1 4.23Å; F188-L229 HydrophobicContact CD2-CB 3.62Å; F188-L229 HydrophobicContact CD2-CD1 4.43Å; F188-L229 HydrophobicContact CE2-CB 3.72Å; F188-L229 HydrophobicContact CG-CB 4.27Å; F188-L229 HydrophobicContact CG-CD1 4.32Å; F188-L229 HydrophobicContact CZ-CB 4.43Å; V225-L229 HydrophobicContact CG1-CD1 3.96Å; V225-L229 HydrophobicContact CG1-CG 4.36Å; V225-L229 VanDerWaalsContact O-CG 3.3Å; V225-L229 WeakPolarHBondContact O-CG 3.34Å; V225-L229 PolarHBondContact O-N 3.28Å; E226-L229 PolarHBondContact O-N 2.92Å; E226-L229 VanDerWaalsContact O-N 3.12Å; L229-V232 PolarHBondContact O-N 3.06Å; L229-K233 WeakPolarHBondContact O-CB 3.05Å; L229-K233 PolarHBondContact O-N 3.08Å; L229-L255 HydrophobicContact CD2-CD2 4.13Å; L229-L255 HydrophobicContact CG-CD2 4.29Å; L229-C258 HydrophobicContact CD1-CB 3.82Å; L229-C258 HydrophobicContact CD2-CB 3.83Å; L229-C258 HydrophobicContact CG-CB 4.47Å; L229-A260 HydrophobicContact CD2-CB 4.12Å
230Q95.1Very high95.5Very high1 Ų122.9 Ų22.91%0.00513%0.128CC..Hα-helixtrans-65.8-40.3174.7-65.7-63.8-11.900112.1F185 E186 F188 L204 E226 I228 V232 K233 Q234F185-Q230 HydrophobicContact CD2-CG 4.21Å; F185-Q230 HydrophobicContact CE2-CG 4.38Å; E186-Q230 PolarHBondContact O-NE2 2.81Å; F188-Q230 HydrophobicContact CD2-CG 4.41Å; F188-Q230 HydrophobicContact CE2-CG 4.44Å; L204-Q230 HydrophobicContact CD1-CB 3.77Å; L204-Q230 HydrophobicContact CD1-CG 4.08Å; L204-Q230 HydrophobicContact CD2-CB 3.81Å; L204-Q230 HydrophobicContact CG-CB 4.43Å; E226-Q230 HydrophobicContact CG-CG 4.47Å; E226-Q230 WeakPolarHBondContact O-CG 3.38Å; E226-Q230 PolarHBondContact O-N 2.7Å; E226-Q230 PolarHBondContact OE1-NE2 3.29Å; I228-Q230 VanDerWaalsContact C-N 3.35Å; I228-Q230 PolarHBondContact O-N 3.46Å; Q230-V232 PolarHBondContact O-N 2.83Å; Q230-K233 WeakPolarHBondContact O-CB 3.3Å; Q230-K233 PolarHBondContact O-N 3.21Å; Q230-Q234 VanDerWaalsContact O-CG 3.32Å; Q230-Q234 WeakPolarHBondContact O-CG 3.39Å; Q230-Q234 PolarHBondContact O-N 2.82Å
231A94.5Very high95.6Very high0 Ų022 Ų220%013%0.125CC..Hα-helixtrans-60.6-44.5173.200000112I227 I228 Q234 G235 Q236 V238 W371I227-A231 PolarHBondContact O-N 2.86Å; I228-A231 WeakPolarHBondContact O-CB 3.5Å; I228-A231 PolarHBondContact O-N 3.38Å; A231-Q234 CarbonylContact O-C 3.51Å; A231-Q234 WeakPolarHBondContact O-CA 3.38Å; A231-Q234 WeakPolarHBondContact O-CB 3.4Å; A231-Q234 PolarHBondContact O-N 2.83Å; A231-Q234 VanDerWaalsContact O-N 3.16Å; A231-G235 PolarHBondContact O-N 2.85Å; A231-Q236 HydrophobicContact CB-CB 4.26Å; A231-Q236 VanDerWaalsContact O-CB 3.29Å; A231-Q236 WeakPolarHBondContact O-CB 3.26Å; A231-Q236 WeakPolarHBondContact O-CG 3.21Å; A231-Q236 PolarHBondContact O-N 3.34Å; A231-V238 HydrophobicContact CB-CG2 3.9Å; A231-W371 HydrophobicContact CB-CD2 4.02Å; A231-W371 HydrophobicContact CB-CE3 3.57Å; A231-W371 HydrophobicContact CB-CH2 3.95Å; A231-W371 HydrophobicContact CB-CZ2 4.34Å; A231-W371 HydrophobicContact CB-CZ3 3.54Å
232V94.8Very high95.7Very high33 Ų3321 Ų2120%0.212%0.118CC..Hα-helixtrans-65.9-37.4176.4171.50000111.7I228 L229 Q230 Q234 G235 V238 D346 V347I228-V232 HydrophobicContact CG2-CG2 4.48Å; I228-V232 WeakPolarHBondContact O-CG2 3.25Å; I228-V232 PolarHBondContact O-N 2.69Å; L229-V232 PolarHBondContact O-N 3.06Å; Q230-V232 PolarHBondContact O-N 2.83Å; V232-Q234 PolarHBondContact O-N 2.57Å; V232-G235 WeakPolarHBondContact O-CA 3.42Å; V232-G235 PolarHBondContact O-N 2.92Å; V232-V238 HydrophobicContact CG2-CG2 4.28Å; V232-D346 HydrophobicContact CG1-CB 3.87Å; V232-D346 HydrophobicContact CG2-CB 4.16Å; V232-V347 HydrophobicContact CG2-CG2 3.6Å
233K93.4Very high95.5Very high114 Ų11421 Ų2150%0.49612%0.119SC..Hα-helixtrans-59.9-34.5172.2-166.8-176.5-174.71730111.8F188 L229 Q230 G235F188-K233 HydrophobicContact CE2-CB 4.12Å; F188-K233 HydrophobicContact CE2-CD 3.85Å; F188-K233 HydrophobicContact CE2-CG 4.46Å; F188-K233 HydrophobicContact CZ-CB 3.96Å; F188-K233 HydrophobicContact CZ-CD 3.7Å; F188-K233 HydrophobicContact CZ-CG 4.06Å; L229-K233 WeakPolarHBondContact O-CB 3.05Å; L229-K233 PolarHBondContact O-N 3.08Å; Q230-K233 WeakPolarHBondContact O-CB 3.3Å; Q230-K233 PolarHBondContact O-N 3.21Å; K233-G235 PolarHBondContact O-N 3.49Å
234Q91.6Very high95Very high78 Ų7822.9 Ų22.936%0.36413%0.132SC..THydrogen-bonded Turntrans-81.711.2173.4-64.1169.812.800113.5Q230 A231 V232 Q236Q230-Q234 VanDerWaalsContact O-CG 3.32Å; Q230-Q234 WeakPolarHBondContact O-CG 3.39Å; Q230-Q234 PolarHBondContact O-N 2.82Å; A231-Q234 CarbonylContact O-C 3.51Å; A231-Q234 WeakPolarHBondContact O-CA 3.38Å; A231-Q234 WeakPolarHBondContact O-CB 3.4Å; A231-Q234 PolarHBondContact O-N 2.83Å; A231-Q234 VanDerWaalsContact O-N 3.16Å; V232-Q234 PolarHBondContact O-N 2.57Å; Q234-Q236 HydrophobicContact CB-CG 4.24Å; Q234-Q236 PolarHBondContact O-N 2.92Å; Q234-Q236 PolarHBondContact O-NE2 3.01Å
235G92.6Very high94.3Very high61 Ų6124.6 Ų24.663%0.62914%0.141SC*.THydrogen-bonded Turntrans70.79.2178.800000115.2A231 V232 K233A231-G235 PolarHBondContact O-N 2.85Å; V232-G235 WeakPolarHBondContact O-CA 3.42Å; V232-G235 PolarHBondContact O-N 2.92Å; K233-G235 PolarHBondContact O-N 3.49Å
236Q94.7Very high93.6Very high39 Ų3928.2 Ų28.218%0.18216%0.163CC..  trans-74.3143.9179.7-53.9-62.7-79.400110.9A231 Q234 D370 W371 R393A231-Q236 HydrophobicContact CB-CB 4.26Å; A231-Q236 VanDerWaalsContact O-CB 3.29Å; A231-Q236 WeakPolarHBondContact O-CB 3.26Å; A231-Q236 WeakPolarHBondContact O-CG 3.21Å; A231-Q236 PolarHBondContact O-N 3.34Å; Q234-Q236 HydrophobicContact CB-CG 4.24Å; Q234-Q236 PolarHBondContact O-N 2.92Å; Q234-Q236 PolarHBondContact O-NE2 3.01Å; Q236-D370 WeakPolarHBondContact CA-OD2 3.15Å; Q236-D370 HydrophobicContact CB-CB 4.09Å; Q236-D370 VanDerWaalsContact OE1-CB 3.25Å; Q236-D370 VanDerWaalsContact OE1-CG 3.29Å; Q236-D370 PolarHBondContact OE1-OD1 3.31Å; Q236-W371 HydrophobicContact CG-CZ2 4.46Å; Q236-R393 VanDerWaalsContact OE1-NH2 3.08Å
237K95.8Very high93.2Very high44 Ų4428.3 Ų28.319%0.19117%0.165CC..  trans-93.5127.2171.8-66.8-61.2-173.9173.30110.6A345 D346 H368 F369 D370 W371K237-A345 PolarHBondContact NZ-O 3.37Å; K237-D346 IonicContact NZ-OD1 3.63Å; K237-D346 PolarHBondContact NZ-OD1 2.97Å; K237-H368 VanDerWaalsContact CB-O 3.29Å; K237-H368 WeakPolarHBondContact CB-O 3.5Å; K237-F369 HydrophobicContact CB-CD1 4.39Å; K237-D370 PolarHBondContact N-OD2 3.31Å; K237-D370 PolarHBondContact O-N 3.03Å; K237-W371 PolarHBondContact O-N 3.12Å
238V97.6Very high92.9Very high0 Ų028.3 Ų28.30%017%0.165CC..EExtended strand (participates in β ladder)trans-116.7129.1-169-169.10000111.9I228 A231 V232 D346 V347 V348 W371 V373I228-V238 HydrophobicContact CG1-CG1 4.45Å; I228-V238 HydrophobicContact CG2-CG1 4.45Å; A231-V238 HydrophobicContact CB-CG2 3.9Å; V232-V238 HydrophobicContact CG2-CG2 4.28Å; V238-D346 PolarHBondContact N-O 2.92Å; V238-D346 VanDerWaalsContact N-O 3.14Å; V238-V347 HydrophobicContact CB-CG1 4.38Å; V238-V347 WeakPolarHBondContact O-CA 3.4Å; V238-V348 PolarHBondContact O-N 3.45Å; V238-W371 HydrophobicContact CG1-CB 4.45Å; V238-V373 HydrophobicContact CG1-CG2 3.76Å
239L97.5Very high92.5Very high0 Ų028.5 Ų28.50%017%0.166CC..EExtended strand (participates in β ladder)trans-101.4105.8168.8175.656.9000109.6V348 A355 L361 F369 W371 V372 V373 A388 R391L239-V348 WeakPolarHBondContact CA-O 3.26Å; L239-V348 HydrophobicContact CD1-CB 4.41Å; L239-V348 HydrophobicContact CD1-CG1 4.42Å; L239-A355 HydrophobicContact CD2-CB 4.39Å; L239-L361 HydrophobicContact CD1-CD1 4.06Å; L239-L361 HydrophobicContact CD2-CD1 3.98Å; L239-F369 HydrophobicContact CB-CB 4.32Å; L239-F369 HydrophobicContact CB-CD1 3.71Å; L239-F369 HydrophobicContact CB-CD2 4.1Å; L239-F369 HydrophobicContact CB-CE1 3.94Å; L239-F369 HydrophobicContact CB-CE2 4.31Å; L239-F369 HydrophobicContact CB-CG 3.78Å; L239-F369 HydrophobicContact CB-CZ 4.24Å; L239-F369 HydrophobicContact CD1-CZ 4.37Å; L239-F369 HydrophobicContact CD2-CD2 4.16Å; L239-F369 HydrophobicContact CD2-CE2 4.2Å; L239-W371 PolarHBondContact N-O 3.06Å; L239-V372 HydrophobicContact CB-CG2 4Å; L239-V372 HydrophobicContact CD2-CG2 4.08Å; L239-V372 HydrophobicContact CG-CG2 4.28Å; L239-V372 WeakPolarHBondContact O-CA 3.45Å; L239-V373 PolarHBondContact O-N 3.45Å; L239-A388 HydrophobicContact CD2-CB 4.36Å; L239-R391 HydrophobicContact CD2-CB 4.15Å; L239-R391 HydrophobicContact CD2-CG 4.38Å
240C97.6Very high92.1Very high1 Ų130.7 Ų30.71%0.00718%0.177CC..EExtended strand (participates in β ladder)trans-94.2130.8176-580000110.8I228 V347 V348 L349 S350 V373I228-C240 WeakPolarHBondContact CD1-SG 3.01Å; C240-V347 HydrophobicContact CB-CG1 4.32Å; C240-V347 WeakPolarHBondContact SG-CG1 3.22Å; C240-V348 PolarHBondContact N-O 3.45Å; C240-L349 HydrophobicContact CB-CD2 3.84Å; C240-L349 HydrophobicContact CB-CG 3.96Å; C240-L349 WeakPolarHBondContact O-CA 3.43Å; C240-S350 PolarHBondContact O-N 3.18Å; C240-V373 CarbonylContact C-O 3.6Å; C240-V373 WeakPolarHBondContact CA-O 3.27Å
241C96.9Very high92Very high0 Ų030.7 Ų30.70%018%0.177CC..EExtended strand (participates in β ladder)trans-132.4157.5-179-720000111.8S350 N352 V373 I374 D375 A388C241-S350 VanDerWaalsContact CA-O 3.27Å; C241-S350 WeakPolarHBondContact CA-O 3.42Å; C241-N352 WeakPolarHBondContact CB-OD1 3.35Å; C241-V373 PolarHBondContact N-O 2.98Å; C241-I374 HydrophobicContact CB-CG1 4.45Å; C241-I374 CarbonylContact O-C 3.48Å; C241-I374 WeakPolarHBondContact O-CA 3.41Å; C241-D375 PolarHBondContact O-N 3.14Å; C241-A388 HydrophobicContact CB-CB 4.29Å
242A94.6Very high91.9Very high0 Ų030.7 Ų30.70%018%0.177CC..EExtended strand (participates in β ladder)trans-154.2160168.100000109.8S244 A247 V248 S350 T351 N352 D375A242-S244 VanDerWaalsContact C-N 3.35Å; A242-S244 PolarHBondContact O-N 2.94Å; A242-A247 HydrophobicContact CB-CB 3.61Å; A242-V248 HydrophobicContact CB-CG2 3.79Å; A242-S350 PolarHBondContact N-O 2.91Å; A242-T351 CarbonylContact O-C 3.59Å; A242-T351 WeakPolarHBondContact O-CA 3.41Å; A242-N352 WeakPolarHBondContact CA-OD1 3.17Å; A242-N352 PolarHBondContact N-OD1 3.33Å; A242-N352 PolarHBondContact O-N 3.01Å; A242-N352 PolarHBondContact O-OD1 2.82Å; A242-D375 WeakPolarHBondContact CA-O 3.45Å; A242-D375 WeakPolarHBondContact CB-O 3.29Å
243P90.9Very high91.7Very high41 Ų4132 Ų3227%0.26618%0.181SC..SBendtrans-68.5-30.5178.525-32.6000113.4D375 E376 Q379 A380P243-D375 VanDerWaalsContact CD-O 3.23Å; P243-D375 WeakPolarHBondContact CD-O 3.38Å; P243-E376 HydrophobicContact CG-CB 4.15Å; P243-E376 WeakPolarHBondContact CG-O 3.47Å; P243-Q379 HydrophobicContact CG-CB 4.18Å; P243-A380 HydrophobicContact CB-CB 3.98Å; P243-A380 HydrophobicContact CG-CB 4.08Å
244S85.5Confident91.6Very high40 Ų4031 Ų3128%0.2818%0.175SC..SBendtrans-113.2147.7-175.780.30000112.9A242 V246 A247 V248A242-S244 VanDerWaalsContact C-N 3.35Å; A242-S244 PolarHBondContact O-N 2.94Å; S244-V246 VanDerWaalsContact C-N 3.27Å; S244-V246 PolarHBondContact O-N 3.13Å; S244-A247 PolarHBondContact O-N 2.74Å; S244-A247 WeakPolarHBondContact OG-CB 3.3Å; S244-A247 PolarHBondContact OG-N 3.06Å; S244-V248 WeakPolarHBondContact O-CG2 3.39Å; S244-V248 PolarHBondContact O-N 3.28Å
245N83.7Confident91.6Very high36 Ų3627.3 Ų27.319%0.19316%0.157CC..Hα-helixtrans-61.1-36.6176.5-70.4-73.8000112.3A247 V248 D249 R264 T351N245-A247 VanDerWaalsContact C-N 3.35Å; N245-A247 PolarHBondContact O-N 3.13Å; N245-V248 PolarHBondContact O-N 2.75Å; N245-D249 VanDerWaalsContact O-CB 3.26Å; N245-D249 WeakPolarHBondContact O-CB 3.27Å; N245-D249 PolarHBondContact O-N 2.84Å; N245-R264 PolarHBondContact OD1-NH1 3.19Å; N245-T351 WeakPolarHBondContact OD1-CG2 3.26Å
246V82.5Confident91.4Very high87 Ų8725.7 Ų25.753%0.52714%0.138SC..Hα-helixtrans-63-41-179.1-179.10000111.2S244 D249 N250S244-V246 VanDerWaalsContact C-N 3.27Å; S244-V246 PolarHBondContact O-N 3.13Å; V246-D249 PolarHBondContact O-N 3.28Å; V246-N250 WeakPolarHBondContact O-CB 3.5Å; V246-N250 PolarHBondContact O-N 2.84Å; V246-N250 PolarHBondContact O-ND2 2.91Å; V246-N250 PolarHBondContact O-OD1 3.11Å
247A87.6Confident91.1Very high6 Ų632.4 Ų32.45%0.0516%0.162CC..Hα-helixtrans-65.1-44.3176.200000112A242 S244 N245 D249 N250 L251 E376A242-A247 HydrophobicContact CB-CB 3.61Å; S244-A247 PolarHBondContact O-N 2.74Å; S244-A247 WeakPolarHBondContact OG-CB 3.3Å; S244-A247 PolarHBondContact OG-N 3.06Å; N245-A247 VanDerWaalsContact C-N 3.35Å; N245-A247 PolarHBondContact O-N 3.13Å; A247-D249 VanDerWaalsContact C-N 3.33Å; A247-D249 PolarHBondContact O-N 3.38Å; A247-N250 PolarHBondContact O-N 3.33Å; A247-L251 PolarHBondContact O-N 2.97Å; A247-E376 HydrophobicContact CB-CG 4.07Å
248V91.1Very high90.5Very high1 Ų133.4 Ų33.41%0.00617%0.173CC..Hα-helixtrans-60.6-45.1174.9-173.20000110.8A242 S244 N245 N250 L251 V252 L349 S350 T351A242-V248 HydrophobicContact CB-CG2 3.79Å; S244-V248 WeakPolarHBondContact O-CG2 3.39Å; S244-V248 PolarHBondContact O-N 3.28Å; N245-V248 PolarHBondContact O-N 2.75Å; V248-N250 PolarHBondContact O-N 3.03Å; V248-L251 WeakPolarHBondContact O-CB 3.45Å; V248-L251 PolarHBondContact O-N 3.37Å; V248-L251 VanDerWaalsContact O-N 3.14Å; V248-V252 HydrophobicContact CG1-CG2 4.44Å; V248-V252 WeakPolarHBondContact O-CG2 3.45Å; V248-V252 PolarHBondContact O-N 3.4Å; V248-L349 HydrophobicContact CG1-CB 3.89Å; V248-S350 WeakPolarHBondContact CG2-O 3.38Å; V248-T351 HydrophobicContact CG2-CG2 4.06Å
249D88.3Confident89.7Confident4 Ų442.6 Ų42.62%0.02121%0.213CC..Hα-helixtrans-65.7-40-176.6-74.810.3000111.4N245 V246 A247 L251 V252 E253 R264 L271 I275N245-D249 VanDerWaalsContact O-CB 3.26Å; N245-D249 WeakPolarHBondContact O-CB 3.27Å; N245-D249 PolarHBondContact O-N 2.84Å; V246-D249 PolarHBondContact O-N 3.28Å; A247-D249 VanDerWaalsContact C-N 3.33Å; A247-D249 PolarHBondContact O-N 3.38Å; D249-L251 VanDerWaalsContact C-N 3.29Å; D249-L251 PolarHBondContact O-N 3.49Å; D249-V252 PolarHBondContact O-N 3.09Å; D249-V252 VanDerWaalsContact O-N 3.16Å; D249-E253 PolarHBondContact O-N 2.82Å; D249-R264 IonicContact OD1-CZ 3.52Å; D249-R264 VanDerWaalsContact OD1-CZ 3.23Å; D249-R264 IonicContact OD1-NE 2.72Å; D249-R264 PolarHBondContact OD1-NE 3.13Å; D249-R264 IonicContact OD1-NH1 3.64Å; D249-R264 PolarHBondContact OD1-NH1 2.91Å; D249-L271 WeakPolarHBondContact OD1-CD2 3.18Å; D249-L271 WeakPolarHBondContact OD2-CA 3.29Å; D249-I275 HydrophobicContact CB-CD1 3.51Å; D249-I275 WeakPolarHBondContact O-CD1 3.38Å
250N88.2Confident89Confident58 Ų5843.4 Ų43.431%0.3122%0.22SC..Hα-helixtrans-58.4-37.7171.7-71.1-13.3000112.8V246 A247 V248 R254V246-N250 WeakPolarHBondContact O-CB 3.5Å; V246-N250 PolarHBondContact O-N 2.84Å; V246-N250 PolarHBondContact O-ND2 2.91Å; V246-N250 PolarHBondContact O-OD1 3.11Å; A247-N250 PolarHBondContact O-N 3.33Å; V248-N250 PolarHBondContact O-N 3.03Å; N250-R254 WeakPolarHBondContact O-CG 3.49Å; N250-R254 PolarHBondContact O-N 3.38Å
251L92.3Very high88.7Confident1 Ų149.7 Ų49.71%0.00525%0.247CC..Hα-helixtrans-68-45.2173.6-72.3168.4000111.6T221 V224 V225 A247 V248 D249 E253 R254 L255 L349 D375T221-L251 HydrophobicContact CG2-CD2 3.63Å; T221-L251 HydrophobicContact CG2-CG 4.21Å; V224-L251 HydrophobicContact CG1-CD2 3.84Å; V225-L251 HydrophobicContact CG2-CD2 4.08Å; A247-L251 PolarHBondContact O-N 2.97Å; V248-L251 WeakPolarHBondContact O-CB 3.45Å; V248-L251 PolarHBondContact O-N 3.37Å; V248-L251 VanDerWaalsContact O-N 3.14Å; D249-L251 VanDerWaalsContact C-N 3.29Å; D249-L251 PolarHBondContact O-N 3.49Å; L251-E253 VanDerWaalsContact C-N 3.33Å; L251-E253 PolarHBondContact O-N 2.98Å; L251-R254 PolarHBondContact O-N 3.14Å; L251-L255 WeakPolarHBondContact O-CB 3.23Å; L251-L255 WeakPolarHBondContact O-CG 3.33Å; L251-L255 PolarHBondContact O-N 2.86Å; L251-L349 HydrophobicContact CB-CD2 3.74Å; L251-D375 HydrophobicContact CD1-CB 3.91Å
252V92.8Very high88.6Confident0 Ų050 Ų500%025%0.249CC..Hα-helixtrans-58.9-45.8178.5-177.80000110.5V248 D249 R254 A256 V262 R264 I275 H278 L349V248-V252 HydrophobicContact CG1-CG2 4.44Å; V248-V252 WeakPolarHBondContact O-CG2 3.45Å; V248-V252 PolarHBondContact O-N 3.4Å; D249-V252 PolarHBondContact O-N 3.09Å; D249-V252 VanDerWaalsContact O-N 3.16Å; V252-R254 PolarHBondContact O-N 3.07Å; V252-A256 WeakPolarHBondContact O-CB 3.41Å; V252-A256 PolarHBondContact O-N 3.13Å; V252-V262 HydrophobicContact CG1-CG2 4.22Å; V252-R264 HydrophobicContact CG2-CB 4.02Å; V252-R264 HydrophobicContact CG2-CG 4.19Å; V252-I275 HydrophobicContact CB-CG2 4.05Å; V252-I275 HydrophobicContact CG1-CG2 3.76Å; V252-I275 HydrophobicContact CG2-CG2 4.44Å; V252-H278 HydrophobicContact CG1-CB 3.92Å; V252-L349 HydrophobicContact CG2-CB 3.86Å; V252-L349 HydrophobicContact CG2-CD1 4.12Å; V252-L349 HydrophobicContact CG2-CD2 3.83Å; V252-L349 HydrophobicContact CG2-CG 4.13Å
253E90.1Very high88.6Confident60 Ų6050.1 Ų50.128%0.2825%0.25SC..Hα-helixtrans-60-45.4-179.8-176.9175.7-16700112.1D249 L251 R257 I275D249-E253 PolarHBondContact O-N 2.82Å; L251-E253 VanDerWaalsContact C-N 3.33Å; L251-E253 PolarHBondContact O-N 2.98Å; E253-R257 WeakPolarHBondContact O-CG 3.42Å; E253-R257 PolarHBondContact O-N 3.19Å; E253-R257 IonicContact OE1-CZ 3.71Å; E253-R257 IonicContact OE1-NE 2.8Å; E253-R257 IonicContact OE1-NH2 3.98Å; E253-R257 PolarHBondContact OE1-NH2 3.44Å; E253-I275 HydrophobicContact CB-CD1 4.24Å; E253-I275 HydrophobicContact CB-CG1 4.43Å
254R91Very high88.6Confident95 Ų9548.2 Ų48.236%0.35824%0.237SC..Hα-helixtrans-68.1-46.8-178.9-70.7170.1173.1-126.2-1.4112T222 V225 N250 L251 V252 A256 R257 C258T222-R254 PolarHBondContact OG1-NH1 2.88Å; V225-R254 HydrophobicContact CG1-CB 4.42Å; V225-R254 HydrophobicContact CG2-CB 3.71Å; N250-R254 WeakPolarHBondContact O-CG 3.49Å; N250-R254 PolarHBondContact O-N 3.38Å; L251-R254 PolarHBondContact O-N 3.14Å; V252-R254 PolarHBondContact O-N 3.07Å; R254-A256 VanDerWaalsContact C-N 3.34Å; R254-A256 PolarHBondContact O-N 2.9Å; R254-R257 PolarHBondContact O-N 2.87Å; R254-C258 PolarHBondContact O-N 3.03Å; R254-C258 PolarHBondContact O-SG 2.83Å; R254-C258 VanDerWaalsContact O-SG 3.41Å
255L92.6Very high88.8Confident0 Ų046.7 Ų46.70%023%0.226CC..Hα-helixtrans-64.9-36.1177.9-70.1163.8000112.6V225 I228 L229 L251 R257 C258 K259 A260 V262 V347 L349V225-L255 HydrophobicContact CG1-CD2 4.01Å; V225-L255 HydrophobicContact CG1-CG 4.47Å; V225-L255 HydrophobicContact CG2-CD2 4.41Å; V225-L255 HydrophobicContact CG2-CG 4.24Å; I228-L255 HydrophobicContact CB-CD2 4.07Å; I228-L255 HydrophobicContact CD1-CD1 4.27Å; I228-L255 HydrophobicContact CG2-CD1 4.33Å; I228-L255 HydrophobicContact CG2-CD2 3.69Å; L229-L255 HydrophobicContact CD2-CD2 4.13Å; L229-L255 HydrophobicContact CG-CD2 4.29Å; L251-L255 WeakPolarHBondContact O-CB 3.23Å; L251-L255 WeakPolarHBondContact O-CG 3.33Å; L251-L255 PolarHBondContact O-N 2.86Å; L255-R257 PolarHBondContact O-N 2.91Å; L255-C258 CarbonylContact O-C 3.49Å; L255-C258 PolarHBondContact O-N 3.14Å; L255-C258 VanDerWaalsContact O-N 3.16Å; L255-K259 PolarHBondContact O-N 2.87Å; L255-A260 PolarHBondContact O-N 2.76Å; L255-V262 HydrophobicContact CB-CG1 3.5Å; L255-V262 HydrophobicContact CD1-CG1 4.24Å; L255-V262 HydrophobicContact CG-CG1 4.48Å; L255-V347 HydrophobicContact CD1-CG1 4.13Å; L255-L349 HydrophobicContact CD1-CD1 4.35Å; L255-L349 HydrophobicContact CD1-CD2 3.84Å
256A88.3Confident88.4Confident26 Ų2646.4 Ų46.422%0.21523%0.231CC..Hα-helixtrans-64.2-37.517600000112.6V252 R254 C258 K259 V262 H278V252-A256 WeakPolarHBondContact O-CB 3.41Å; V252-A256 PolarHBondContact O-N 3.13Å; R254-A256 VanDerWaalsContact C-N 3.34Å; R254-A256 PolarHBondContact O-N 2.9Å; A256-C258 PolarHBondContact O-N 3.25Å; A256-K259 PolarHBondContact O-N 2.68Å; A256-K259 VanDerWaalsContact O-N 3.13Å; A256-V262 HydrophobicContact CB-CG2 4.18Å; A256-H278 WeakPolarHBondContact CB-NE2 3.34Å
257R87.3Confident87.5Confident181 Ų18145.3 Ų45.368%0.68322%0.22SC*.Hα-helixtrans-61.8-33.7173.4-68.9169.3-173.5-158.74.4111.7E253 R254 L255 K259E253-R257 WeakPolarHBondContact O-CG 3.42Å; E253-R257 PolarHBondContact O-N 3.19Å; E253-R257 IonicContact OE1-CZ 3.71Å; E253-R257 IonicContact OE1-NE 2.8Å; E253-R257 IonicContact OE1-NH2 3.98Å; E253-R257 PolarHBondContact OE1-NH2 3.44Å; R254-R257 PolarHBondContact O-N 2.87Å; L255-R257 PolarHBondContact O-N 2.91Å; R257-K259 PolarHBondContact O-N 3.08Å
258C84.2Confident86.1Confident64 Ų6446.2 Ų46.243%0.43223%0.226SC..THydrogen-bonded Turntrans-81.39.5176.4-57.10000114.2L229 R254 L255 A256 A260L229-C258 HydrophobicContact CD1-CB 3.82Å; L229-C258 HydrophobicContact CD2-CB 3.83Å; L229-C258 HydrophobicContact CG-CB 4.47Å; R254-C258 PolarHBondContact O-N 3.03Å; R254-C258 PolarHBondContact O-SG 2.83Å; R254-C258 VanDerWaalsContact O-SG 3.41Å; L255-C258 CarbonylContact O-C 3.49Å; L255-C258 PolarHBondContact O-N 3.14Å; L255-C258 VanDerWaalsContact O-N 3.16Å; A256-C258 PolarHBondContact O-N 3.25Å; C258-A260 PolarHBondContact O-N 2.71Å
259K80.8Confident84.1Confident194 Ų19447.5 Ų47.584%0.84324%0.237SC*.THydrogen-bonded Turntrans6018.2179.2-55.3-179.3-179.1174.50115.8L255 A256 R257L255-K259 PolarHBondContact O-N 2.87Å; A256-K259 PolarHBondContact O-N 2.68Å; A256-K259 VanDerWaalsContact O-N 3.13Å; R257-K259 PolarHBondContact O-N 3.08Å
260A83.8Confident82.7Confident17 Ų1751.2 Ų51.214%0.1425%0.25CS..  trans-66.8147.2172.600000111.3L229 L255 C258 V262L229-A260 HydrophobicContact CD2-CB 4.12Å; L255-A260 PolarHBondContact O-N 2.76Å; C258-A260 PolarHBondContact O-N 2.71Å; A260-V262 VanDerWaalsContact C-N 3.3Å; A260-V262 HydrophobicContact CB-CG1 4.18Å; A260-V262 PolarHBondContact O-N 3.43Å
261K90.7Very high81.5Confident132 Ų13249 Ų4957%0.57424%0.238SC*.  trans-75.982.9174.7-61.4-177.6-167.7160.10110.5D346 V347K261-D346 HydrophobicContact CB-CB 4.29Å; K261-D346 WeakPolarHBondContact CB-OD2 3.33Å; K261-D346 WeakPolarHBondContact CD-OD2 3.41Å; K261-D346 WeakPolarHBondContact CG-OD2 3.31Å; K261-D346 PolarHBondContact O-N 3.24Å; K261-V347 PolarHBondContact O-N 2.93Å
262V93.8Very high80.2Confident8 Ų853.2 Ų53.25%0.04826%0.261CS..EExtended strand (participates in β ladder)trans-90.5138.2-179.1-64.60000112.6V252 L255 A256 A260 H278 V347 L349V252-V262 HydrophobicContact CG1-CG2 4.22Å; L255-V262 HydrophobicContact CB-CG1 3.5Å; L255-V262 HydrophobicContact CD1-CG1 4.24Å; L255-V262 HydrophobicContact CG-CG1 4.48Å; A256-V262 HydrophobicContact CB-CG2 4.18Å; A260-V262 VanDerWaalsContact C-N 3.3Å; A260-V262 HydrophobicContact CB-CG1 4.18Å; A260-V262 PolarHBondContact O-N 3.43Å; V262-H278 HydrophobicContact CG2-CB 4.2Å; V262-H278 WeakPolarHBondContact CG2-ND1 3.35Å; V262-V347 WeakPolarHBondContact CA-O 3.33Å; V262-V347 HydrophobicContact CG1-CB 4.35Å; V262-L349 HydrophobicContact CB-CD1 3.78Å; V262-L349 HydrophobicContact CG1-CD1 3.93Å
263L94.3Very high79Confident2 Ų261.2 Ų61.21%0.0130%0.298CS..EExtended strand (participates in β ladder)trans-128.2115.6174.4173.362.7000110.4L265 L280 I283 I341 L342 A345 V347 V348 L349L263-L265 HydrophobicContact CD2-CD2 4.15Å; L263-L265 HydrophobicContact CG-CD2 4.03Å; L263-L280 HydrophobicContact CD1-CB 4.12Å; L263-L280 HydrophobicContact CD1-CD1 4.06Å; L263-I283 HydrophobicContact CD1-CD1 3.68Å; L263-I341 HydrophobicContact CD1-CG2 3.88Å; L263-I341 HydrophobicContact CD2-CG2 3.93Å; L263-L342 HydrophobicContact CD2-CD2 3.7Å; L263-L342 HydrophobicContact CD2-CG 4.16Å; L263-A345 HydrophobicContact CB-CB 3.7Å; L263-A345 HydrophobicContact CD2-CB 4.12Å; L263-V347 PolarHBondContact N-O 3.43Å; L263-V348 HydrophobicContact CD2-CG2 4.4Å; L263-V348 WeakPolarHBondContact O-CA 3.49Å; L263-L349 PolarHBondContact O-N 2.98Å
264R92.8Very high78.3Confident1 Ų161.5 Ų61.50%0.00431%0.306CS..EExtended strand (participates in β ladder)trans-92.6112.3178176.754.7161.5114.4-177.4110.9N245 D249 V252 L271 I275 H278 S279 L280 L349N245-R264 PolarHBondContact OD1-NH1 3.19Å; D249-R264 IonicContact OD1-CZ 3.52Å; D249-R264 VanDerWaalsContact OD1-CZ 3.23Å; D249-R264 IonicContact OD1-NE 2.72Å; D249-R264 PolarHBondContact OD1-NE 3.13Å; D249-R264 IonicContact OD1-NH1 3.64Å; D249-R264 PolarHBondContact OD1-NH1 2.91Å; V252-R264 HydrophobicContact CG2-CB 4.02Å; V252-R264 HydrophobicContact CG2-CG 4.19Å; R264-L271 HydrophobicContact CG-CD1 3.91Å; R264-L271 HydrophobicContact CG-CD2 3.79Å; R264-I275 HydrophobicContact CG-CG2 4.49Å; R264-H278 PolarHBondContact N-O 3.13Å; R264-S279 WeakPolarHBondContact O-CA 3.46Å; R264-L280 PolarHBondContact O-N 3.25Å; R264-L349 CarbonylContact C-O 3.6Å; R264-L349 WeakPolarHBondContact CA-O 3.39Å; R264-L349 WeakPolarHBondContact CD-O 3.46Å
265L88.9Confident77.8Confident7 Ų757 Ų574%0.03729%0.29CS..  trans-86.1116.6170.3-50.5-176.1000109.6L263 L280 L342 V348 L349 P360 L361L263-L265 HydrophobicContact CD2-CD2 4.15Å; L263-L265 HydrophobicContact CG-CD2 4.03Å; L265-L280 HydrophobicContact CD2-CB 4.19Å; L265-L280 HydrophobicContact CD2-CD2 4.13Å; L265-L342 HydrophobicContact CD1-CD2 4.36Å; L265-L342 HydrophobicContact CD2-CD2 4.09Å; L265-V348 HydrophobicContact CD1-CG1 3.56Å; L265-V348 HydrophobicContact CD2-CG1 4.31Å; L265-V348 HydrophobicContact CG-CG1 3.68Å; L265-L349 PolarHBondContact N-O 3.34Å; L265-P360 HydrophobicContact CD1-CB 4.21Å; L265-P360 HydrophobicContact CD1-CG 4.39Å; L265-P360 HydrophobicContact CD2-CB 4.16Å; L265-P360 HydrophobicContact CD2-CG 4.27Å; L265-L361 HydrophobicContact CD1-CD2 3.52Å; L265-L361 HydrophobicContact CD1-CG 3.85Å
266G74.2Confident77.2Confident30 Ų3060.6 Ų60.631%0.30931%0.306SS..SBendtrans163.7163.8-178.500000110.7
267H65.6Low77Confident64 Ų6465.2 Ų65.230%0.29632%0.322SS..  trans-74.1129.1179.6-163-80.3000110.7A84 T108 A269 R270A84-H267 HydrophobicContact CB-CB 3.82Å; T108-H267 WeakPolarHBondContact CB-NE2 3.37Å; T108-H267 WeakPolarHBondContact CG2-NE2 3.34Å; T108-H267 PolarHBondContact O-CE1 3.04Å; T108-H267 PolarHBondContact O-ND1 3.06Å; H267-A269 VanDerWaalsContact C-N 3.29Å; H267-A269 PolarHBondContact O-N 2.81Å; H267-A269 VanDerWaalsContact O-N 3.12Å; H267-R270 WeakPolarHBondContact O-CB 3.2Å; H267-R270 PolarHBondContact O-N 3.12Å
268P56.8Low77.1Confident26 Ų2658.4 Ų58.417%0.16930%0.297CS..G310 helixtrans-54.5-36.7-172.3-31.535.6000115.3R270 L271 D281P268-R270 PolarHBondContact O-N 3.26Å; P268-L271 WeakPolarHBondContact O-CB 3.12Å; P268-L271 PolarHBondContact O-N 3.24Å; P268-D281 WeakPolarHBondContact CD-OD2 3.44Å; P268-D281 HydrophobicContact CG-CB 3.68Å; P268-D281 WeakPolarHBondContact CG-OD2 3.3Å
269A49.8Very low77.2Confident28 Ų2855.4 Ų55.423%0.23128%0.277CS..G310 helixtrans-71-4.717800000115P83 A84 T108 R109 H267P83-A269 WeakPolarHBondContact CB-O 3.37Å; P83-A269 WeakPolarHBondContact O-CB 3.46Å; A84-A269 HydrophobicContact CB-CB 4.28Å; T108-A269 WeakPolarHBondContact O-CB 3.48Å; R109-A269 HydrophobicContact CB-CB 4.39Å; R109-A269 HydrophobicContact CG-CB 4.42Å; H267-A269 VanDerWaalsContact C-N 3.29Å; H267-A269 PolarHBondContact O-N 2.81Å; H267-A269 VanDerWaalsContact O-N 3.12Å
270R58.8Low77.4Confident82 Ų8246.3 Ų46.331%0.30924%0.238SC..G310 helixtrans-86.7-12165.4-93.7166.2178.3-164.7-2.9113.2A84 G85 H267 P268A84-R270 VanDerWaalsContact C-NE 3.33Å; A84-R270 HydrophobicContact CB-CG 3.9Å; A84-R270 PolarHBondContact O-NE 3.35Å; A84-R270 PolarHBondContact O-NH2 3.46Å; G85-R270 PolarHBondContact O-NH2 3.47Å; G85-R270 VanDerWaalsContact O-NH2 3.11Å; H267-R270 WeakPolarHBondContact O-CB 3.2Å; H267-R270 PolarHBondContact O-N 3.12Å; P268-R270 PolarHBondContact O-N 3.26Å
271L63.4Low77.2Confident10 Ų1047 Ų475%0.05224%0.239CC..SBendtrans-99.6145.1-170-48.6178.3000111.3D249 R264 P268 I275 Q276D249-L271 WeakPolarHBondContact OD1-CD2 3.18Å; D249-L271 WeakPolarHBondContact OD2-CA 3.29Å; R264-L271 HydrophobicContact CG-CD1 3.91Å; R264-L271 HydrophobicContact CG-CD2 3.79Å; P268-L271 WeakPolarHBondContact O-CB 3.12Å; P268-L271 PolarHBondContact O-N 3.24Å; L271-I275 HydrophobicContact CB-CG2 4.38Å; L271-I275 HydrophobicContact CD1-CG2 4.49Å; L271-Q276 HydrophobicContact CB-CG 4.04Å; L271-Q276 PolarHBondContact O-NE2 2.95Å
272L64Low76.8Confident91 Ų9141.8 Ų41.848%0.47622%0.22SC..  trans-57.4143.5165.8-62.9167.3000110.3S274 I275 Q276L272-S274 VanDerWaalsContact C-N 3.28Å; L272-S274 PolarHBondContact O-N 3.26Å; L272-I275 HydrophobicContact CB-CB 4.5Å; L272-I275 HydrophobicContact CB-CD1 4.04Å; L272-I275 HydrophobicContact CB-CG1 4.35Å; L272-I275 HydrophobicContact CD1-CD1 4.01Å; L272-I275 HydrophobicContact CG-CD1 4.46Å; L272-I275 WeakPolarHBondContact O-CA 3.36Å; L272-I275 WeakPolarHBondContact O-CB 3.23Å; L272-I275 PolarHBondContact O-N 3.47Å; L272-Q276 PolarHBondContact O-N 3.08Å; L272-Q276 VanDerWaalsContact O-N 3.1Å
273E67.9Low76.4Confident167 Ų16743.5 Ų43.578%0.7823%0.229SC*.Hα-helixtrans-57-39.7-175.7-173.9171.9-165.500112.7I275 Q276E273-I275 PolarHBondContact O-N 2.73Å; E273-I275 VanDerWaalsContact O-N 3.14Å; E273-Q276 PolarHBondContact O-N 2.95Å
274S75.3Confident75.9Confident66 Ų6643.9 Ų43.946%0.46223%0.231SC..Hα-helixtrans-58.6-24173.653.90000114.1L272 K277L272-S274 VanDerWaalsContact C-N 3.28Å; L272-S274 PolarHBondContact O-N 3.26Å; S274-K277 WeakPolarHBondContact O-CE 3.36Å
275I81.6Confident75.3Confident2 Ų247.3 Ų47.31%0.0126%0.259CS..Hα-helixtrans-99.9-21.4-176-65172.5000111.7D249 V252 E253 R264 L271 L272 E273 K277 H278D249-I275 HydrophobicContact CB-CD1 3.51Å; D249-I275 WeakPolarHBondContact O-CD1 3.38Å; V252-I275 HydrophobicContact CB-CG2 4.05Å; V252-I275 HydrophobicContact CG1-CG2 3.76Å; V252-I275 HydrophobicContact CG2-CG2 4.44Å; E253-I275 HydrophobicContact CB-CD1 4.24Å; E253-I275 HydrophobicContact CB-CG1 4.43Å; R264-I275 HydrophobicContact CG-CG2 4.49Å; L271-I275 HydrophobicContact CB-CG2 4.38Å; L271-I275 HydrophobicContact CD1-CG2 4.49Å; L272-I275 HydrophobicContact CB-CB 4.5Å; L272-I275 HydrophobicContact CB-CD1 4.04Å; L272-I275 HydrophobicContact CB-CG1 4.35Å; L272-I275 HydrophobicContact CD1-CD1 4.01Å; L272-I275 HydrophobicContact CG-CD1 4.46Å; L272-I275 WeakPolarHBondContact O-CA 3.36Å; L272-I275 WeakPolarHBondContact O-CB 3.23Å; L272-I275 PolarHBondContact O-N 3.47Å; E273-I275 PolarHBondContact O-N 2.73Å; E273-I275 VanDerWaalsContact O-N 3.14Å; I275-K277 PolarHBondContact O-N 3.39Å; I275-K277 VanDerWaalsContact O-N 3.09Å; I275-H278 WeakPolarHBondContact O-CB 3.32Å; I275-H278 PolarHBondContact O-N 3.37Å
276Q79.1Confident74.9Confident74 Ų7453.8 Ų53.835%0.34629%0.289SS..Hα-helixtrans-55.3-34.4-176.3-74.7178.619.500112.9L271 L272 E273 H278 S279 A282L271-Q276 HydrophobicContact CB-CG 4.04Å; L271-Q276 PolarHBondContact O-NE2 2.95Å; L272-Q276 PolarHBondContact O-N 3.08Å; L272-Q276 VanDerWaalsContact O-N 3.1Å; E273-Q276 PolarHBondContact O-N 2.95Å; Q276-H278 PolarHBondContact O-N 3.06Å; Q276-S279 VanDerWaalsContact O-CB 3.26Å; Q276-S279 WeakPolarHBondContact O-CB 3.32Å; Q276-S279 PolarHBondContact O-N 3.18Å; Q276-S279 PolarHBondContact O-OG 3.37Å; Q276-A282 WeakPolarHBondContact O-CB 3.19Å
277K84.8Confident75.2Confident124 Ų12453.7 Ų53.754%0.53928%0.284SS..THydrogen-bonded Turntrans-58.7-22173.462.4175.7174.6167.80115.1S274 I275S274-K277 WeakPolarHBondContact O-CE 3.36Å; I275-K277 PolarHBondContact O-N 3.39Å; I275-K277 VanDerWaalsContact O-N 3.09Å
278H87.6Confident75.6Confident37 Ų3758.1 Ų58.117%0.17131%0.31CS..THydrogen-bonded Turntrans-97.10.3176.5-61.4-67.8000113V252 A256 V262 R264 I275 Q276V252-H278 HydrophobicContact CG1-CB 3.92Å; A256-H278 WeakPolarHBondContact CB-NE2 3.34Å; V262-H278 HydrophobicContact CG2-CB 4.2Å; V262-H278 WeakPolarHBondContact CG2-ND1 3.35Å; R264-H278 PolarHBondContact N-O 3.13Å; I275-H278 WeakPolarHBondContact O-CB 3.32Å; I275-H278 PolarHBondContact O-N 3.37Å; Q276-H278 PolarHBondContact O-N 3.06Å
279S87.7Confident76.5Confident1 Ų159.6 Ų59.61%0.00732%0.316CS..BIsolated β-bridgetrans-71.3148.3175.971.40000111.6R264 Q276 D281 A282 I283R264-S279 WeakPolarHBondContact O-CA 3.46Å; Q276-S279 VanDerWaalsContact O-CB 3.26Å; Q276-S279 WeakPolarHBondContact O-CB 3.32Å; Q276-S279 PolarHBondContact O-N 3.18Å; Q276-S279 PolarHBondContact O-OG 3.37Å; S279-D281 PolarHBondContact O-N 2.87Å; S279-A282 PolarHBondContact O-N 2.76Å; S279-A282 VanDerWaalsContact O-N 3.17Å; S279-A282 WeakPolarHBondContact OG-CB 3.44Å; S279-A282 PolarHBondContact OG-N 2.79Å; S279-I283 WeakPolarHBondContact O-CG1 3.44Å; S279-I283 PolarHBondContact O-N 3.35Å
280L84.9Confident77.8Confident4 Ų459 Ų592%0.02131%0.312CS..Hα-helixtrans-49.8-43.1173.9-179.764.1000111.7L263 R264 L265 I283 L284 I338 I341 P360L263-L280 HydrophobicContact CD1-CB 4.12Å; L263-L280 HydrophobicContact CD1-CD1 4.06Å; R264-L280 PolarHBondContact O-N 3.25Å; L265-L280 HydrophobicContact CD2-CB 4.19Å; L265-L280 HydrophobicContact CD2-CD2 4.13Å; L280-I283 PolarHBondContact O-N 3.27Å; L280-L284 HydrophobicContact CD1-CD1 4.29Å; L280-L284 HydrophobicContact CD1-CG 4.36Å; L280-L284 HydrophobicContact CG-CD1 3.93Å; L280-L284 HydrophobicContact CG-CG 4.45Å; L280-L284 WeakPolarHBondContact O-CB 3.29Å; L280-L284 VanDerWaalsContact O-CG 3.23Å; L280-L284 WeakPolarHBondContact O-CG 3.3Å; L280-L284 PolarHBondContact O-N 2.73Å; L280-I338 HydrophobicContact CD1-CG1 4.31Å; L280-I338 HydrophobicContact CD1-CG2 4.34Å; L280-I338 HydrophobicContact CD2-CG1 4.29Å; L280-I338 HydrophobicContact CD2-CG2 4.26Å; L280-I341 HydrophobicContact CD1-CG2 4.04Å; L280-P360 HydrophobicContact CD2-CB 4.06Å; L280-P360 HydrophobicContact CD2-CG 3.84Å
281D80.2Confident78.8Confident31 Ų3160.9 Ų60.917%0.16633%0.328CS..Hα-helixtrans-69.1-37.8-176-57.3-5.8000112.4L57 P268 S279 A285L57-D281 HydrophobicContact CD1-CB 4.13Å; L57-D281 WeakPolarHBondContact CD1-OD1 3.47Å; L57-D281 WeakPolarHBondContact CD1-OD2 3.34Å; P268-D281 WeakPolarHBondContact CD-OD2 3.44Å; P268-D281 HydrophobicContact CG-CB 3.68Å; P268-D281 WeakPolarHBondContact CG-OD2 3.3Å; S279-D281 PolarHBondContact O-N 2.87Å; D281-A285 WeakPolarHBondContact O-CB 3.36Å; D281-A285 PolarHBondContact O-N 3.3Å
282A81.5Confident79.6Confident22 Ų2263.9 Ų63.918%0.18234%0.343CS..Hα-helixtrans-71.7-39.5176.100000112.1Q276 S279 A285 Q286Q276-A282 WeakPolarHBondContact O-CB 3.19Å; S279-A282 PolarHBondContact O-N 2.76Å; S279-A282 VanDerWaalsContact O-N 3.17Å; S279-A282 WeakPolarHBondContact OG-CB 3.44Å; S279-A282 PolarHBondContact OG-N 2.79Å; A282-A285 PolarHBondContact O-N 2.67Å; A282-Q286 WeakPolarHBondContact O-CG 3.49Å; A282-Q286 PolarHBondContact O-N 3.16Å; A282-Q286 VanDerWaalsContact O-N 3.09Å
283I84.9Confident80.4Confident44 Ų4460 Ų6023%0.22632%0.322CS..Hα-helixtrans-68.3-40.7177.1-63.3165.2000110.1L263 S279 L280 A285 Q286 S287 I341L263-I283 HydrophobicContact CD1-CD1 3.68Å; S279-I283 WeakPolarHBondContact O-CG1 3.44Å; S279-I283 PolarHBondContact O-N 3.35Å; L280-I283 PolarHBondContact O-N 3.27Å; I283-A285 VanDerWaalsContact C-N 3.32Å; I283-A285 PolarHBondContact O-N 3.24Å; I283-Q286 CarbonylContact O-C 3.54Å; I283-Q286 PolarHBondContact O-N 3.26Å; I283-Q286 VanDerWaalsContact O-N 3.14Å; I283-S287 PolarHBondContact O-N 2.93Å; I283-I341 HydrophobicContact CB-CG2 4.47Å; I283-I341 HydrophobicContact CG2-CD1 3.97Å; I283-I341 HydrophobicContact CG2-CG1 4.05Å; I283-I341 HydrophobicContact CG2-CG2 3.78Å
284L84.4Confident81Confident11 Ų1154 Ų546%0.05830%0.301CS..Hα-helixtrans-57.2-44.3170.6-79.6167.4000111.9L57 L280 Q286 S287 A290 A337 I338 I341L57-L284 HydrophobicContact CD2-CD1 4.36Å; L280-L284 HydrophobicContact CD1-CD1 4.29Å; L280-L284 HydrophobicContact CD1-CG 4.36Å; L280-L284 HydrophobicContact CG-CD1 3.93Å; L280-L284 HydrophobicContact CG-CG 4.45Å; L280-L284 WeakPolarHBondContact O-CB 3.29Å; L280-L284 VanDerWaalsContact O-CG 3.23Å; L280-L284 WeakPolarHBondContact O-CG 3.3Å; L280-L284 PolarHBondContact O-N 2.73Å; L284-Q286 PolarHBondContact O-N 3.11Å; L284-S287 PolarHBondContact O-N 3.02Å; L284-S287 PolarHBondContact O-OG 2.92Å; L284-A290 WeakPolarHBondContact O-CB 3.42Å; L284-A337 HydrophobicContact CD2-CB 3.74Å; L284-I338 HydrophobicContact CD1-CD1 4.25Å; L284-I338 HydrophobicContact CD1-CG1 3.78Å; L284-I338 HydrophobicContact CD2-CG1 3.91Å; L284-I338 HydrophobicContact CG-CG1 4.32Å; L284-I341 HydrophobicContact CB-CD1 4.49Å; L284-I341 HydrophobicContact CD2-CD1 3.52Å; L284-I341 HydrophobicContact CG-CD1 3.82Å
285A80.1Confident81.4Confident72 Ų7254.4 Ų54.460%0.59530%0.299SS*.Hα-helixtrans-69.4-15.9178.500000114.2D281 A282 I283 A290D281-A285 WeakPolarHBondContact O-CB 3.36Å; D281-A285 PolarHBondContact O-N 3.3Å; A282-A285 PolarHBondContact O-N 2.67Å; I283-A285 VanDerWaalsContact C-N 3.32Å; I283-A285 PolarHBondContact O-N 3.24Å; A285-A290 WeakPolarHBondContact O-CB 3.34Å
286Q80.1Confident81.5Confident144 Ų14454.8 Ų54.867%0.67330%0.3SS*.Hα-helixtrans-101.3-9.1175.6-69.4172.921.200113.3A282 I283 L284A282-Q286 WeakPolarHBondContact O-CG 3.49Å; A282-Q286 PolarHBondContact O-N 3.16Å; A282-Q286 VanDerWaalsContact O-N 3.09Å; I283-Q286 CarbonylContact O-C 3.54Å; I283-Q286 PolarHBondContact O-N 3.26Å; I283-Q286 VanDerWaalsContact O-N 3.14Å; L284-Q286 PolarHBondContact O-N 3.11Å
287S79.7Confident81.6Confident27 Ų2754.5 Ų54.519%0.18930%0.296CS..SBendtrans-71.3156.9179.671.90000112.6I283 L284 N289 A290I283-S287 PolarHBondContact O-N 2.93Å; L284-S287 PolarHBondContact O-N 3.02Å; L284-S287 PolarHBondContact O-OG 2.92Å; S287-N289 PolarHBondContact O-N 3.44Å; S287-N289 VanDerWaalsContact O-N 3.11Å; S287-A290 WeakPolarHBondContact O-CB 3.43Å; S287-A290 PolarHBondContact O-N 2.95Å
288D75.8Confident81.6Confident158 Ų15853.9 Ų53.985%0.84529%0.294SS*.THydrogen-bonded Turntrans-59.6-27.1178.1-57.3-49000112.7A290D288-A290 VanDerWaalsContact C-N 3.26Å; D288-A290 PolarHBondContact O-N 3.26Å
289N74.6Confident81.4Confident56 Ų5655 Ų5530%0.29930%0.301SS..THydrogen-bonded Turntrans-73.5-11174.5-71-54.8000113.9S287 N291 I292 I293 A337S287-N289 PolarHBondContact O-N 3.44Å; S287-N289 VanDerWaalsContact O-N 3.11Å; N289-N291 PolarHBondContact O-N 2.83Å; N289-I292 PolarHBondContact O-N 2.88Å; N289-I293 HydrophobicContact CB-CD1 4.33Å; N289-I293 WeakPolarHBondContact O-CG1 3.28Å; N289-I293 PolarHBondContact O-N 2.92Å; N289-A337 HydrophobicContact CB-CB 4.41Å
290A76.8Confident81.2Confident17 Ų1755 Ų5514%0.1430%0.301CS..Hα-helixtrans-61.4-40.1-174.600000113.1L284 A285 S287 D288 I292 I293 A294L284-A290 WeakPolarHBondContact O-CB 3.42Å; A285-A290 WeakPolarHBondContact O-CB 3.34Å; S287-A290 WeakPolarHBondContact O-CB 3.43Å; S287-A290 PolarHBondContact O-N 2.95Å; D288-A290 VanDerWaalsContact C-N 3.26Å; D288-A290 PolarHBondContact O-N 3.26Å; A290-I292 VanDerWaalsContact C-N 3.35Å; A290-I292 PolarHBondContact O-N 3.3Å; A290-I293 PolarHBondContact O-N 2.76Å; A290-A294 VanDerWaalsContact O-CB 3.3Å; A290-A294 WeakPolarHBondContact O-CB 3.46Å; A290-A294 PolarHBondContact O-N 3.4Å
291N79.8Confident81Confident121 Ų12157.4 Ų57.465%0.64731%0.314SS*.Hα-helixtrans-60.2-46.7178.6-68.7-39.3000111N289 I293 A294 D295N289-N291 PolarHBondContact O-N 2.83Å; N291-I293 PolarHBondContact O-N 3.06Å; N291-A294 PolarHBondContact O-N 3.4Å; N291-D295 PolarHBondContact O-N 2.89Å
292I81Confident81.1Confident72 Ų7262.2 Ų62.237%0.36933%0.333SS..Hα-helixtrans-64.3-43.3179.2-57.8173.3000110.7N289 A290 A294 D295 I296N289-I292 PolarHBondContact O-N 2.88Å; A290-I292 VanDerWaalsContact C-N 3.35Å; A290-I292 PolarHBondContact O-N 3.3Å; I292-A294 VanDerWaalsContact C-N 3.34Å; I292-D295 PolarHBondContact O-N 3.31Å; I292-I296 HydrophobicContact CG2-CD1 4.42Å; I292-I296 WeakPolarHBondContact O-CG1 3.14Å; I292-I296 PolarHBondContact O-N 3.23Å; I292-I296 VanDerWaalsContact O-N 3.12Å
293I81.4Confident81.1Confident9 Ų961.3 Ų61.35%0.04633%0.326CS..Hα-helixtrans-63.6-40.8176.3-70.7168.3000110.9N289 A290 N291 R297 L330 E334N289-I293 HydrophobicContact CB-CD1 4.33Å; N289-I293 WeakPolarHBondContact O-CG1 3.28Å; N289-I293 PolarHBondContact O-N 2.92Å; A290-I293 PolarHBondContact O-N 2.76Å; N291-I293 PolarHBondContact O-N 3.06Å; I293-R297 WeakPolarHBondContact O-CG 3.28Å; I293-R297 PolarHBondContact O-N 2.98Å; I293-R297 VanDerWaalsContact O-N 3.11Å; I293-L330 HydrophobicContact CG2-CD1 3.9Å; I293-E334 HydrophobicContact CD1-CG 4.25Å; I293-E334 HydrophobicContact CG2-CG 4.4Å
294A79.9Confident80.6Confident41 Ų4160.9 Ų60.934%0.33932%0.324SS..Hα-helixtrans-65.5-38.5177.700000112.2A290 N291 I292 R297 K298A290-A294 VanDerWaalsContact O-CB 3.3Å; A290-A294 WeakPolarHBondContact O-CB 3.46Å; A290-A294 PolarHBondContact O-N 3.4Å; N291-A294 PolarHBondContact O-N 3.4Å; I292-A294 VanDerWaalsContact C-N 3.34Å; A294-R297 PolarHBondContact O-N 2.81Å; A294-K298 WeakPolarHBondContact O-CG 3.47Å; A294-K298 PolarHBondContact O-N 2.84Å
295D84Confident80.3Confident76 Ų7664.1 Ų64.141%0.40634%0.344SS..Hα-helixtrans-69.3-43.7178.2-70.7-25.3000112.2N291 I292 R297 K298 D299N291-D295 PolarHBondContact O-N 2.89Å; I292-D295 PolarHBondContact O-N 3.31Å; D295-R297 VanDerWaalsContact C-N 3.27Å; D295-R297 PolarHBondContact O-N 2.85Å; D295-K298 WeakPolarHBondContact O-CB 3.31Å; D295-K298 PolarHBondContact O-N 2.83Å; D295-K298 VanDerWaalsContact O-N 3.12Å; D295-K298 IonicContact OD1-NZ 3.86Å; D295-K298 PolarHBondContact OD1-NZ 3.39Å; D295-D299 PolarHBondContact O-N 2.87Å
296I82.2Confident80Confident9 Ų961.6 Ų61.65%0.04633%0.325CS..Hα-helixtrans-57.7-41.6172.2-58.8159.3000111I292 D299 I300 L326 E329 L330I292-I296 HydrophobicContact CG2-CD1 4.42Å; I292-I296 WeakPolarHBondContact O-CG1 3.14Å; I292-I296 PolarHBondContact O-N 3.23Å; I292-I296 VanDerWaalsContact O-N 3.12Å; I296-D299 PolarHBondContact O-N 3.18Å; I296-I300 HydrophobicContact CG2-CD1 3.96Å; I296-I300 HydrophobicContact CG2-CG1 4.39Å; I296-I300 WeakPolarHBondContact O-CG1 3.47Å; I296-I300 PolarHBondContact O-N 2.89Å; I296-L326 HydrophobicContact CG2-CB 4.23Å; I296-L326 HydrophobicContact CG2-CD2 4.34Å; I296-E329 HydrophobicContact CD1-CG 4.21Å; I296-L330 HydrophobicContact CB-CD1 4.37Å; I296-L330 HydrophobicContact CG2-CB 3.87Å; I296-L330 HydrophobicContact CG2-CD1 4.35Å
297R81.7Confident79.6Confident69 Ų6957.7 Ų57.726%0.2631%0.307SS..Hα-helixtrans-63.3-42.6177.1-73.3177.6-174.5176.13.6111.9I293 A294 D295 D299 I300 D301 L330 E334I293-R297 WeakPolarHBondContact O-CG 3.28Å; I293-R297 PolarHBondContact O-N 2.98Å; I293-R297 VanDerWaalsContact O-N 3.11Å; A294-R297 PolarHBondContact O-N 2.81Å; D295-R297 VanDerWaalsContact C-N 3.27Å; D295-R297 PolarHBondContact O-N 2.85Å; R297-D299 VanDerWaalsContact C-N 3.28Å; R297-D299 PolarHBondContact O-N 3.03Å; R297-I300 PolarHBondContact O-N 3.08Å; R297-D301 PolarHBondContact O-N 3.03Å; R297-L330 HydrophobicContact CG-CD1 4.11Å; R297-L330 HydrophobicContact CG-CD2 4.16Å; R297-E334 IonicContact CZ-OE1 2.78Å; R297-E334 IonicContact NE-OE1 3.57Å; R297-E334 IonicContact NH2-OE1 2.81Å; R297-E334 PolarHBondContact NH2-OE1 3.21Å
298K84.2Confident79Confident110 Ų11062.3 Ų62.348%0.47832%0.324SS..Hα-helixtrans-58.6-40.5173.5-68.5166.5-160.2161.40111.3A294 D295 D301 K302A294-K298 WeakPolarHBondContact O-CG 3.47Å; A294-K298 PolarHBondContact O-N 2.84Å; D295-K298 WeakPolarHBondContact O-CB 3.31Å; D295-K298 PolarHBondContact O-N 2.83Å; D295-K298 VanDerWaalsContact O-N 3.12Å; D295-K298 IonicContact OD1-NZ 3.86Å; D295-K298 PolarHBondContact OD1-NZ 3.39Å; K298-D301 PolarHBondContact O-N 2.58Å; K298-K302 VanDerWaalsContact O-CG 3.25Å; K298-K302 WeakPolarHBondContact O-CG 3.41Å; K298-K302 PolarHBondContact O-N 3.13Å
299D85.1Confident78.7Confident62 Ų6263.1 Ų63.133%0.33232%0.32SS..Hα-helixtrans-72.3-37.7-178.6-67.5-23000112.5D295 I296 R297 D301 K302 A303 L326D295-D299 PolarHBondContact O-N 2.87Å; I296-D299 PolarHBondContact O-N 3.18Å; R297-D299 VanDerWaalsContact C-N 3.28Å; R297-D299 PolarHBondContact O-N 3.03Å; D299-D301 PolarHBondContact O-N 3.46Å; D299-K302 PolarHBondContact O-N 3.22Å; D299-K302 WeakPolarHBondContact OD1-CE 3.47Å; D299-K302 IonicContact OD1-NZ 3.52Å; D299-K302 PolarHBondContact OD1-NZ 3.21Å; D299-A303 WeakPolarHBondContact O-CB 3.31Å; D299-A303 PolarHBondContact O-N 3.03Å; D299-L326 HydrophobicContact CB-CD1 4.08Å
300I81.9Confident78Confident0 Ų064.9 Ų64.90%033%0.325CS..Hα-helixtrans-59.5-46.4168.8-66.4166.2000110.7T55 I296 R297 A303 L304 I323 L326 R327 L330T55-I300 HydrophobicContact CG2-CD1 4.35Å; T55-I300 HydrophobicContact CG2-CG2 4.22Å; T55-I300 VanDerWaalsContact OG1-CG2 3.31Å; T55-I300 WeakPolarHBondContact OG1-CG2 3.35Å; I296-I300 HydrophobicContact CG2-CD1 3.96Å; I296-I300 HydrophobicContact CG2-CG1 4.39Å; I296-I300 WeakPolarHBondContact O-CG1 3.47Å; I296-I300 PolarHBondContact O-N 2.89Å; R297-I300 PolarHBondContact O-N 3.08Å; I300-A303 PolarHBondContact O-N 2.88Å; I300-L304 HydrophobicContact CG2-CD1 4.02Å; I300-L304 HydrophobicContact CG2-CG 4.45Å; I300-L304 WeakPolarHBondContact O-CG 3.37Å; I300-L304 PolarHBondContact O-N 3.05Å; I300-I323 HydrophobicContact CG2-CG2 4.47Å; I300-L326 HydrophobicContact CD1-CB 4.09Å; I300-L326 HydrophobicContact CG1-CB 3.55Å; I300-L326 HydrophobicContact CG1-CD1 4.12Å; I300-L326 HydrophobicContact CG1-CG 4.47Å; I300-R327 HydrophobicContact CD1-CG 4.08Å; I300-L330 HydrophobicContact CD1-CB 4.45Å; I300-L330 HydrophobicContact CD1-CD2 3.84Å
301D80.8Confident76.7Confident55 Ų5569.6 Ų69.629%0.29436%0.357SS..Hα-helixtrans-68.1-36.1-178.8-71.1-12.1000111.7T55 R297 K298 D299 L304 V305T55-D301 WeakPolarHBondContact CB-OD1 3.37Å; T55-D301 PolarHBondContact N-OD1 3.01Å; T55-D301 PolarHBondContact OG1-OD1 3.48Å; R297-D301 PolarHBondContact O-N 3.03Å; K298-D301 PolarHBondContact O-N 2.58Å; D299-D301 PolarHBondContact O-N 3.46Å; D301-L304 PolarHBondContact O-N 2.99Å; D301-V305 WeakPolarHBondContact O-CG2 3.23Å; D301-V305 PolarHBondContact O-N 2.7Å
302K83.6Confident75.7Confident131 Ų13170.2 Ų70.257%0.5736%0.356SS*.Hα-helixtrans-59.5-48.2169.2-73.1169-160.6163.80111.4K298 D299 L304 V305 G306K298-K302 VanDerWaalsContact O-CG 3.25Å; K298-K302 WeakPolarHBondContact O-CG 3.41Å; K298-K302 PolarHBondContact O-N 3.13Å; D299-K302 PolarHBondContact O-N 3.22Å; D299-K302 WeakPolarHBondContact OD1-CE 3.47Å; D299-K302 IonicContact OD1-NZ 3.52Å; D299-K302 PolarHBondContact OD1-NZ 3.21Å; K302-L304 VanDerWaalsContact C-N 3.34Å; K302-L304 PolarHBondContact O-N 3.04Å; K302-V305 PolarHBondContact O-N 2.91Å; K302-G306 PolarHBondContact O-N 2.92Å
303A80.6Confident74.5Confident3 Ų376.4 Ų76.43%0.02538%0.38CS..Hα-helixtrans-64.4-36.9179.600000112D299 I300 G306 M307 F319 I323D299-A303 WeakPolarHBondContact O-CB 3.31Å; D299-A303 PolarHBondContact O-N 3.03Å; I300-A303 PolarHBondContact O-N 2.88Å; A303-G306 PolarHBondContact O-N 2.83Å; A303-M307 WeakPolarHBondContact O-CB 3.46Å; A303-M307 PolarHBondContact O-N 2.92Å; A303-F319 HydrophobicContact CB-CD1 4.32Å; A303-I323 HydrophobicContact CB-CD1 3.99Å; A303-I323 HydrophobicContact CB-CG1 3.58Å
304L75Confident73.6Confident36 Ų3678.5 Ų78.519%0.18840%0.404CS..Hα-helixtrans-62.6-41.3172.3-75.5169.1000112.4I300 D301 K302 K308 I323I300-L304 HydrophobicContact CG2-CD1 4.02Å; I300-L304 HydrophobicContact CG2-CG 4.45Å; I300-L304 WeakPolarHBondContact O-CG 3.37Å; I300-L304 PolarHBondContact O-N 3.05Å; D301-L304 PolarHBondContact O-N 2.99Å; K302-L304 VanDerWaalsContact C-N 3.34Å; K302-L304 PolarHBondContact O-N 3.04Å; L304-K308 PolarHBondContact O-N 2.93Å; L304-K308 VanDerWaalsContact O-N 3.1Å; L304-I323 HydrophobicContact CD2-CD1 3.91Å; L304-I323 HydrophobicContact CG-CD1 4.1Å
305V77.4Confident73Confident78 Ų7879.7 Ų79.747%0.47340%0.403SS..Hα-helixtrans-67.5-40.8174.5172.40000111.4D301 K302 K308 K309D301-V305 WeakPolarHBondContact O-CG2 3.23Å; D301-V305 PolarHBondContact O-N 2.7Å; K302-V305 PolarHBondContact O-N 2.91Å; V305-K308 PolarHBondContact O-N 2.85Å; V305-K309 HydrophobicContact CG1-CD 4.21Å; V305-K309 PolarHBondContact O-N 3.37Å
306G74.8Confident72.2Confident19 Ų1980.8 Ų80.820%0.19640%0.401CS..Hα-helixtrans-58.3-46.7173.700000112.3K302 A303 K308 K309 K310K302-G306 PolarHBondContact O-N 2.92Å; A303-G306 PolarHBondContact O-N 2.83Å; G306-K308 VanDerWaalsContact C-N 3.32Å; G306-K308 PolarHBondContact O-N 2.8Å; G306-K309 PolarHBondContact O-N 3.24Å; G306-K310 PolarHBondContact O-N 2.81Å
307M71.8Confident71.8Confident63 Ų6381.9 Ų81.931%0.3141%0.414SS..Hα-helixtrans-62.2-32.9176-178.5-178.1145.300113.1A303 R316 F319 I323A303-M307 WeakPolarHBondContact O-CB 3.46Å; A303-M307 PolarHBondContact O-N 2.92Å; M307-R316 VanDerWaalsContact O-CZ 3.3Å; M307-R316 PolarHBondContact O-NH1 2.9Å; M307-F319 HydrophobicContact CB-CB 4.24Å; M307-I323 HydrophobicContact SD-CD1 4.42Å
308K67.2Low71.8Confident123 Ų12383.4 Ų83.454%0.53543%0.428SS..Hα-helixtrans-73.1-39.1174-76.2-173.1-179.3-178.80112.7L304 V305 G306L304-K308 PolarHBondContact O-N 2.93Å; L304-K308 VanDerWaalsContact O-N 3.1Å; V305-K308 PolarHBondContact O-N 2.85Å; G306-K308 VanDerWaalsContact C-N 3.32Å; G306-K308 PolarHBondContact O-N 2.8Å
309K68.1Low71.5Confident176 Ų17680.3 Ų80.377%0.76541%0.414SS*.Hα-helixtrans-76.3-22.7-174-75.7-175.8177-177.90115.4V305 G306V305-K309 HydrophobicContact CG1-CD 4.21Å; V305-K309 PolarHBondContact O-N 3.37Å; G306-K309 PolarHBondContact O-N 3.24Å
310K60.1Low71.1Confident93 Ų9383.9 Ų83.940%0.40443%0.427SS..  trans-112.3134.6-173.5-67-156.8179.8-177.90113.9G306 E315 R316G306-K310 PolarHBondContact O-N 2.81Å; K310-E315 WeakPolarHBondContact CD-OE2 3.24Å; K310-E315 WeakPolarHBondContact CE-OE2 3.45Å; K310-E315 IonicContact NZ-OE1 2.65Å; K310-E315 PolarHBondContact NZ-OE1 3.26Å; K310-E315 IonicContact NZ-OE2 2.68Å; K310-E315 PolarHBondContact NZ-OE2 3.49Å; K310-R316 PolarHBondContact O-NH1 3.12Å
311S50.2Low71.1Confident116 Ų11692.4 Ų92.481%0.81146%0.459SS*.  trans-91.6-16-171.2-160.60000114.6
312E57.9Low71.3Confident133 Ų13393.9 Ų93.962%0.62146%0.464SS*.  trans-73.3133.6-173.2-67.2-165.7169.700113.7G314 R316E312-G314 VanDerWaalsContact C-N 3.27Å; E312-G314 PolarHBondContact O-N 3.2Å; E312-R316 WeakPolarHBondContact O-CG 3.27Å; E312-R316 PolarHBondContact O-N 2.77Å
313K57.1Low71.3Confident203 Ų20388.2 Ų88.288%0.88344%0.44SS*.THydrogen-bonded Turntrans-66.5-27-173.9-155174.7-174.4179.10113.1
314G63Low71.3Confident53 Ų5389.7 Ų89.755%0.54646%0.456SS..THydrogen-bonded Turntrans-75-54176.400000112.9E312 R316 G317 N318E312-G314 VanDerWaalsContact C-N 3.27Å; E312-G314 PolarHBondContact O-N 3.2Å; G314-R316 VanDerWaalsContact C-N 3.33Å; G314-R316 PolarHBondContact O-N 2.85Å; G314-G317 WeakPolarHBondContact O-CA 3.34Å; G314-G317 PolarHBondContact O-N 3.23Å; G314-N318 PolarHBondContact O-N 2.89Å
315E66.1Low71.9Confident66 Ų6694.4 Ų94.431%0.30848%0.477SS..Hα-helixtrans-62.4-36.6-179-67.3-167.2134.200112.7K310 G317 N318 F319K310-E315 WeakPolarHBondContact CD-OE2 3.24Å; K310-E315 WeakPolarHBondContact CE-OE2 3.45Å; K310-E315 IonicContact NZ-OE1 2.65Å; K310-E315 PolarHBondContact NZ-OE1 3.26Å; K310-E315 IonicContact NZ-OE2 2.68Å; K310-E315 PolarHBondContact NZ-OE2 3.49Å; E315-G317 PolarHBondContact O-N 3.17Å; E315-N318 PolarHBondContact O-N 3.24Å; E315-N318 VanDerWaalsContact O-N 3.09Å; E315-F319 HydrophobicContact CB-CE2 4.43Å; E315-F319 VanDerWaalsContact O-CD2 3.24Å; E315-F319 WeakPolarHBondContact O-CD2 3.42Å; E315-F319 PolarHBondContact O-N 3.28Å; E315-F319 VanDerWaalsContact O-N 3.13Å
316R68.7Low72.3Confident99 Ų9992 Ų9237%0.37446%0.461SS..Hα-helixtrans-58.2-29.9172.3-73.4176.7100.398.5-7.8112.9M307 K310 E312 G314 K320M307-R316 VanDerWaalsContact O-CZ 3.3Å; M307-R316 PolarHBondContact O-NH1 2.9Å; K310-R316 PolarHBondContact O-NH1 3.12Å; E312-R316 WeakPolarHBondContact O-CG 3.27Å; E312-R316 PolarHBondContact O-N 2.77Å; G314-R316 VanDerWaalsContact C-N 3.33Å; G314-R316 PolarHBondContact O-N 2.85Å; R316-K320 WeakPolarHBondContact O-CB 3.37Å; R316-K320 PolarHBondContact O-N 3.31Å; R316-K320 VanDerWaalsContact O-N 3.12Å
317G73.4Confident72.7Confident32 Ų3292.9 Ų92.933%0.3346%0.459SS..Hα-helixtrans-68.2-39.7175.100000112.8G314 E315 K320 R321G314-G317 WeakPolarHBondContact O-CA 3.34Å; G314-G317 PolarHBondContact O-N 3.23Å; E315-G317 PolarHBondContact O-N 3.17Å; G317-K320 PolarHBondContact O-N 3.21Å; G317-R321 PolarHBondContact O-N 2.87Å
318N80.6Confident73.3Confident101 Ų10196.1 Ų96.154%0.5447%0.471SS..Hα-helixtrans-68.1-49.2177.9-69.4-9.6000111.1G314 E315 K320 R321 E322G314-N318 PolarHBondContact O-N 2.89Å; E315-N318 PolarHBondContact O-N 3.24Å; E315-N318 VanDerWaalsContact O-N 3.09Å; N318-K320 VanDerWaalsContact C-N 3.27Å; N318-K320 PolarHBondContact O-N 3.44Å; N318-R321 WeakPolarHBondContact O-CB 3.5Å; N318-R321 PolarHBondContact O-N 2.87Å; N318-E322 PolarHBondContact O-N 3.38Å
319F77.6Confident74.2Confident45 Ų4593.9 Ų93.920%0.19746%0.462CS..Hα-helixtrans-58.9-36175-69.6-63.7000112.5A303 M307 E315 R321 E322 I323A303-F319 HydrophobicContact CB-CD1 4.32Å; M307-F319 HydrophobicContact CB-CB 4.24Å; E315-F319 HydrophobicContact CB-CE2 4.43Å; E315-F319 VanDerWaalsContact O-CD2 3.24Å; E315-F319 WeakPolarHBondContact O-CD2 3.42Å; E315-F319 PolarHBondContact O-N 3.28Å; E315-F319 VanDerWaalsContact O-N 3.13Å; F319-R321 VanDerWaalsContact C-N 3.33Å; F319-R321 PolarHBondContact O-N 2.83Å; F319-E322 VanDerWaalsContact CD1-OE2 3.27Å; F319-E322 WeakPolarHBondContact CD1-OE2 3.44Å; F319-I323 WeakPolarHBondContact O-CB 3.31Å; F319-I323 WeakPolarHBondContact O-CD1 3.44Å; F319-I323 WeakPolarHBondContact O-CG1 3.48Å; F319-I323 PolarHBondContact O-N 3.28Å
320K77.7Confident75Confident137 Ų13785.5 Ų85.560%0.59643%0.426SS*.Hα-helixtrans-65.7-33.5175.3-168.7176.5-178.6-178.10112.5D124 R316 G317 N318 G324D124-K320 IonicContact OD1-NZ 3.61Å; R316-K320 WeakPolarHBondContact O-CB 3.37Å; R316-K320 PolarHBondContact O-N 3.31Å; R316-K320 VanDerWaalsContact O-N 3.12Å; G317-K320 PolarHBondContact O-N 3.21Å; N318-K320 VanDerWaalsContact C-N 3.27Å; N318-K320 PolarHBondContact O-N 3.44Å; K320-G324 PolarHBondContact O-N 2.88Å
321R82.1Confident76.1Confident178 Ų17885 Ų8567%0.67242%0.422SS*.Hα-helixtrans-71.9-49.6174.3-71.7176.5177.6175.2-1.5111.5G317 N318 F319 I323 G324 E325G317-R321 PolarHBondContact O-N 2.87Å; N318-R321 WeakPolarHBondContact O-CB 3.5Å; N318-R321 PolarHBondContact O-N 2.87Å; F319-R321 VanDerWaalsContact C-N 3.33Å; F319-R321 PolarHBondContact O-N 2.83Å; R321-I323 PolarHBondContact O-N 2.66Å; R321-G324 CarbonylContact O-C 3.56Å; R321-G324 WeakPolarHBondContact O-CA 3.34Å; R321-G324 PolarHBondContact O-N 2.91Å; R321-E325 PolarHBondContact O-N 3.39Å
322E85.2Confident77.8Confident86 Ų8684.4 Ų84.440%0.40241%0.409SS..Hα-helixtrans-54.9-49.3176.8-177.2-177.7-169.100111.7N318 F319 G324 E325 L326N318-E322 PolarHBondContact O-N 3.38Å; F319-E322 VanDerWaalsContact CD1-OE2 3.27Å; F319-E322 WeakPolarHBondContact CD1-OE2 3.44Å; E322-G324 VanDerWaalsContact C-N 3.26Å; E322-G324 PolarHBondContact O-N 3.17Å; E322-E325 PolarHBondContact O-N 3.23Å; E322-L326 HydrophobicContact CG-CD1 4.07Å; E322-L326 WeakPolarHBondContact O-CB 3.35Å; E322-L326 WeakPolarHBondContact O-CG 3.26Å; E322-L326 PolarHBondContact O-N 2.85Å
323I82.3Confident79.1Confident12 Ų1282.5 Ų82.56%0.06240%0.396CS..Hα-helixtrans-59.1-37.6173.6-69.4164.7000111.4I300 A303 L304 M307 F319 R321 R327I300-I323 HydrophobicContact CG2-CG2 4.47Å; A303-I323 HydrophobicContact CB-CD1 3.99Å; A303-I323 HydrophobicContact CB-CG1 3.58Å; L304-I323 HydrophobicContact CD2-CD1 3.91Å; L304-I323 HydrophobicContact CG-CD1 4.1Å; M307-I323 HydrophobicContact SD-CD1 4.42Å; F319-I323 WeakPolarHBondContact O-CB 3.31Å; F319-I323 WeakPolarHBondContact O-CD1 3.44Å; F319-I323 WeakPolarHBondContact O-CG1 3.48Å; F319-I323 PolarHBondContact O-N 3.28Å; R321-I323 PolarHBondContact O-N 2.66Å; I323-R327 HydrophobicContact CG2-CG 4.34Å; I323-R327 VanDerWaalsContact O-CB 3.22Å; I323-R327 WeakPolarHBondContact O-CB 3.4Å; I323-R327 WeakPolarHBondContact O-CG 3.35Å; I323-R327 PolarHBondContact O-N 3.44Å
324G81.4Confident80.4Confident35 Ų3573 Ų7336%0.36136%0.355SS..Hα-helixtrans-65.8-41.5177.200000113.3K320 R321 E322 K328K320-G324 PolarHBondContact O-N 2.88Å; R321-G324 CarbonylContact O-C 3.56Å; R321-G324 WeakPolarHBondContact O-CA 3.34Å; R321-G324 PolarHBondContact O-N 2.91Å; E322-G324 VanDerWaalsContact C-N 3.26Å; E322-G324 PolarHBondContact O-N 3.17Å; G324-K328 PolarHBondContact O-N 2.9Å; G324-K328 VanDerWaalsContact O-N 3.07Å
325E86.9Confident81.5Confident135 Ų13572.7 Ų72.763%0.63134%0.343SS*.Hα-helixtrans-69.4-50177-72.1172.8-175.100111.2R321 E322 R327 K328 E329R321-E325 PolarHBondContact O-N 3.39Å; E322-E325 PolarHBondContact O-N 3.23Å; E325-R327 VanDerWaalsContact C-N 3.32Å; E325-R327 PolarHBondContact O-N 2.84Å; E325-K328 WeakPolarHBondContact O-CA 3.39Å; E325-K328 WeakPolarHBondContact O-CB 3.47Å; E325-K328 PolarHBondContact O-N 2.84Å; E325-E329 PolarHBondContact O-N 2.73Å
326L86Confident82.5Confident27 Ų2772.5 Ų72.514%0.14135%0.352CS..Hα-helixtrans-58.9-40.2175.1-68.3171.8000112I296 D299 I300 E322 K328 E329 L330I296-L326 HydrophobicContact CG2-CB 4.23Å; I296-L326 HydrophobicContact CG2-CD2 4.34Å; D299-L326 HydrophobicContact CB-CD1 4.08Å; I300-L326 HydrophobicContact CD1-CB 4.09Å; I300-L326 HydrophobicContact CG1-CB 3.55Å; I300-L326 HydrophobicContact CG1-CD1 4.12Å; I300-L326 HydrophobicContact CG1-CG 4.47Å; E322-L326 HydrophobicContact CG-CD1 4.07Å; E322-L326 WeakPolarHBondContact O-CB 3.35Å; E322-L326 WeakPolarHBondContact O-CG 3.26Å; E322-L326 PolarHBondContact O-N 2.85Å; L326-K328 VanDerWaalsContact C-N 3.31Å; L326-K328 PolarHBondContact O-N 3.1Å; L326-E329 PolarHBondContact O-N 3.37Å; L326-L330 VanDerWaalsContact O-CB 3.24Å; L326-L330 WeakPolarHBondContact O-CB 3.46Å; L326-L330 PolarHBondContact O-N 3Å
327R82.6Confident83.5Confident37 Ų3767.8 Ų67.814%0.1434%0.335CS..Hα-helixtrans-65-32.2172.6-77.9177-176.5-167.54.2112.8D121 I300 I323 E325 R331D121-R327 IonicContact OD1-CZ 2.75Å; D121-R327 IonicContact OD1-NH1 3.46Å; D121-R327 PolarHBondContact OD1-NH1 2.84Å; I300-R327 HydrophobicContact CD1-CG 4.08Å; I323-R327 HydrophobicContact CG2-CG 4.34Å; I323-R327 VanDerWaalsContact O-CB 3.22Å; I323-R327 WeakPolarHBondContact O-CB 3.4Å; I323-R327 WeakPolarHBondContact O-CG 3.35Å; I323-R327 PolarHBondContact O-N 3.44Å; E325-R327 VanDerWaalsContact C-N 3.32Å; E325-R327 PolarHBondContact O-N 2.84Å; R327-R331 WeakPolarHBondContact O-CB 3.45Å; R327-R331 VanDerWaalsContact O-CG 3.31Å; R327-R331 WeakPolarHBondContact O-CG 3.21Å; R327-R331 PolarHBondContact O-N 2.83Å; R327-R331 VanDerWaalsContact O-N 3.12Å; R327-R331 PolarHBondContact O-NE 2.97Å
328K84.9Confident84.2Confident132 Ų13266.3 Ų66.357%0.57432%0.319SS*.Hα-helixtrans-70.9-44.9175.4-171-176.9178.3-173.70110.6G324 E325 L326 R331 N332G324-K328 PolarHBondContact O-N 2.9Å; G324-K328 VanDerWaalsContact O-N 3.07Å; E325-K328 WeakPolarHBondContact O-CA 3.39Å; E325-K328 WeakPolarHBondContact O-CB 3.47Å; E325-K328 PolarHBondContact O-N 2.84Å; L326-K328 VanDerWaalsContact C-N 3.31Å; L326-K328 PolarHBondContact O-N 3.1Å; K328-R331 PolarHBondContact O-N 3.06Å; K328-N332 WeakPolarHBondContact O-CB 3.36Å; K328-N332 VanDerWaalsContact O-CG 3.23Å; K328-N332 PolarHBondContact O-N 3.13Å; K328-N332 PolarHBondContact O-OD1 3.16Å
329E86.9Confident84.7Confident75 Ų7562.3 Ų62.335%0.3530%0.3SS..Hα-helixtrans-62.7-46.3175.3-172.2174.7173.800111.9I296 E325 L326 R331 N332 R333I296-E329 HydrophobicContact CD1-CG 4.21Å; E325-E329 PolarHBondContact O-N 2.73Å; L326-E329 PolarHBondContact O-N 3.37Å; E329-R331 PolarHBondContact O-N 2.68Å; E329-N332 PolarHBondContact O-N 3.01Å; E329-R333 PolarHBondContact O-N 2.94Å; E329-R333 IonicContact OE1-CZ 3Å; E329-R333 IonicContact OE1-NH1 2.66Å; E329-R333 PolarHBondContact OE1-NH1 3Å; E329-R333 IonicContact OE1-NH2 2.72Å; E329-R333 PolarHBondContact OE1-NH2 3.14Å
330L84.2Confident85.3Confident0 Ų066.2 Ų66.20%032%0.319CS..Hα-helixtrans-54-52.7174.6-178.964.1000111.3T55 I293 I296 R297 I300 L326 N332 R333 E334T55-L330 HydrophobicContact CG2-CD2 4.34Å; I293-L330 HydrophobicContact CG2-CD1 3.9Å; I296-L330 HydrophobicContact CB-CD1 4.37Å; I296-L330 HydrophobicContact CG2-CB 3.87Å; I296-L330 HydrophobicContact CG2-CD1 4.35Å; R297-L330 HydrophobicContact CG-CD1 4.11Å; R297-L330 HydrophobicContact CG-CD2 4.16Å; I300-L330 HydrophobicContact CD1-CB 4.45Å; I300-L330 HydrophobicContact CD1-CD2 3.84Å; L326-L330 VanDerWaalsContact O-CB 3.24Å; L326-L330 WeakPolarHBondContact O-CB 3.46Å; L326-L330 PolarHBondContact O-N 3Å; L330-N332 VanDerWaalsContact C-N 3.31Å; L330-N332 PolarHBondContact O-N 3.34Å; L330-R333 PolarHBondContact O-N 2.94Å; L330-E334 HydrophobicContact CD1-CG 4.07Å; L330-E334 HydrophobicContact CG-CG 4.33Å; L330-E334 WeakPolarHBondContact O-CB 3.36Å; L330-E334 WeakPolarHBondContact O-CG 3.31Å; L330-E334 PolarHBondContact O-N 3.09Å
331R83.1Confident85.9Confident84 Ų8460.5 Ų60.532%0.31730%0.295SS..Hα-helixtrans-62.2-37179.6-76.5179-65.3-1391.2112.7D121 R327 K328 E329 T335D121-R331 IonicContact OD2-NH1 2.7Å; R327-R331 WeakPolarHBondContact O-CB 3.45Å; R327-R331 VanDerWaalsContact O-CG 3.31Å; R327-R331 WeakPolarHBondContact O-CG 3.21Å; R327-R331 PolarHBondContact O-N 2.83Å; R327-R331 VanDerWaalsContact O-N 3.12Å; R327-R331 PolarHBondContact O-NE 2.97Å; K328-R331 PolarHBondContact O-N 3.06Å; E329-R331 PolarHBondContact O-N 2.68Å; R331-T335 WeakPolarHBondContact O-CB 3.47Å; R331-T335 PolarHBondContact O-N 3.14Å; R331-T335 PolarHBondContact O-OG1 2.99Å
332N86.7Confident86.4Confident102 Ų10252 Ų5255%0.54526%0.263SS..Hα-helixtrans-66.3-46.6177.1-72.7-3.1000111.5K328 E329 L330 T335 A336K328-N332 WeakPolarHBondContact O-CB 3.36Å; K328-N332 VanDerWaalsContact O-CG 3.23Å; K328-N332 PolarHBondContact O-N 3.13Å; K328-N332 PolarHBondContact O-OD1 3.16Å; E329-N332 PolarHBondContact O-N 3.01Å; L330-N332 VanDerWaalsContact C-N 3.31Å; L330-N332 PolarHBondContact O-N 3.34Å; N332-T335 PolarHBondContact O-N 3.21Å; N332-A336 PolarHBondContact O-N 2.93Å
333R85Confident86.8Confident94 Ų9453.7 Ų53.736%0.35527%0.269SS..Hα-helixtrans-68-43.9177.2-72.3-163.217811820.4112.5E329 L330 T335 A336 A337E329-R333 PolarHBondContact O-N 2.94Å; E329-R333 IonicContact OE1-CZ 3Å; E329-R333 IonicContact OE1-NH1 2.66Å; E329-R333 PolarHBondContact OE1-NH1 3Å; E329-R333 IonicContact OE1-NH2 2.72Å; E329-R333 PolarHBondContact OE1-NH2 3.14Å; L330-R333 PolarHBondContact O-N 2.94Å; R333-T335 VanDerWaalsContact C-N 3.32Å; R333-T335 PolarHBondContact O-N 2.77Å; R333-A336 PolarHBondContact O-N 3.39Å; R333-A337 PolarHBondContact O-N 3.04Å
334E84.1Confident87.2Confident2 Ų256.4 Ų56.41%0.00929%0.289CS..Hα-helixtrans-58.2-44.5173.6-75.2-175.3165.100110.8Y58 I293 R297 L330 A336 A337 I338Y58-E334 VanDerWaalsContact CA-OE2 3.27Å; Y58-E334 WeakPolarHBondContact CA-OE2 3.25Å; Y58-E334 PolarHBondContact N-OE2 3.24Å; I293-E334 HydrophobicContact CD1-CG 4.25Å; I293-E334 HydrophobicContact CG2-CG 4.4Å; R297-E334 IonicContact CZ-OE1 2.78Å; R297-E334 IonicContact NE-OE1 3.57Å; R297-E334 IonicContact NH2-OE1 2.81Å; R297-E334 PolarHBondContact NH2-OE1 3.21Å; L330-E334 HydrophobicContact CD1-CG 4.07Å; L330-E334 HydrophobicContact CG-CG 4.33Å; L330-E334 WeakPolarHBondContact O-CB 3.36Å; L330-E334 WeakPolarHBondContact O-CG 3.31Å; L330-E334 PolarHBondContact O-N 3.09Å; E334-A336 PolarHBondContact O-N 3.02Å; E334-A337 PolarHBondContact O-N 3.12Å; E334-I338 HydrophobicContact CB-CD1 4.48Å; E334-I338 VanDerWaalsContact O-CB 3.29Å; E334-I338 WeakPolarHBondContact O-CB 3.34Å; E334-I338 WeakPolarHBondContact O-CD1 3.24Å; E334-I338 WeakPolarHBondContact O-CG1 3.48Å; E334-I338 PolarHBondContact O-N 2.7Å
335T86Confident87.8Confident48 Ų4855.1 Ų55.129%0.29427%0.274SS..Hα-helixtrans-60.7-44.7177.3-670000112.5R331 N332 R333 A339 F363R331-T335 WeakPolarHBondContact O-CB 3.47Å; R331-T335 PolarHBondContact O-N 3.14Å; R331-T335 PolarHBondContact O-OG1 2.99Å; N332-T335 PolarHBondContact O-N 3.21Å; R333-T335 VanDerWaalsContact C-N 3.32Å; R333-T335 PolarHBondContact O-N 2.77Å; T335-A339 WeakPolarHBondContact O-CB 3.35Å; T335-A339 PolarHBondContact O-N 3.42Å; T335-F363 HydrophobicContact CG2-CD1 3.61Å; T335-F363 HydrophobicContact CG2-CE1 3.33Å; T335-F363 HydrophobicContact CG2-CG 4.33Å; T335-F363 HydrophobicContact CG2-CZ 3.85Å
336A87.8Confident88.1Confident61 Ų6150.4 Ų50.450%0.50425%0.254SS..Hα-helixtrans-63.1-48.9178.300000111.8N332 R333 E334 I338 A339 E340N332-A336 PolarHBondContact O-N 2.93Å; R333-A336 PolarHBondContact O-N 3.39Å; E334-A336 PolarHBondContact O-N 3.02Å; A336-I338 PolarHBondContact O-N 3.19Å; A336-A339 PolarHBondContact O-N 2.86Å; A336-E340 PolarHBondContact O-N 3.27Å; A336-E340 VanDerWaalsContact O-N 3.09Å
337A88.1Confident88.6Confident1 Ų149.1 Ų49.11%0.00825%0.247CC..Hα-helixtrans-63.3-41.5178.500000112.3L284 N289 R333 E334 A339 E340 I341L284-A337 HydrophobicContact CD2-CB 3.74Å; N289-A337 HydrophobicContact CB-CB 4.41Å; R333-A337 PolarHBondContact O-N 3.04Å; E334-A337 PolarHBondContact O-N 3.12Å; A337-A339 VanDerWaalsContact C-N 3.34Å; A337-A339 PolarHBondContact O-N 3.18Å; A337-E340 PolarHBondContact O-N 3.42Å; A337-I341 WeakPolarHBondContact O-CB 3.29Å; A337-I341 WeakPolarHBondContact O-CD1 3.36Å; A337-I341 VanDerWaalsContact O-CG1 3.28Å; A337-I341 WeakPolarHBondContact O-CG1 3.35Å; A337-I341 PolarHBondContact O-N 3.35Å
338I89.2Confident89.3Confident1 Ų147.4 Ų47.41%0.00524%0.24CC..Hα-helixtrans-60-44.2174.4-71165.2000110.7Y58 L280 L284 E334 A336 E340 I341 L342 P360 F363Y58-I338 HydrophobicContact CE1-CD1 3.65Å; L280-I338 HydrophobicContact CD1-CG1 4.31Å; L280-I338 HydrophobicContact CD1-CG2 4.34Å; L280-I338 HydrophobicContact CD2-CG1 4.29Å; L280-I338 HydrophobicContact CD2-CG2 4.26Å; L284-I338 HydrophobicContact CD1-CD1 4.25Å; L284-I338 HydrophobicContact CD1-CG1 3.78Å; L284-I338 HydrophobicContact CD2-CG1 3.91Å; L284-I338 HydrophobicContact CG-CG1 4.32Å; E334-I338 HydrophobicContact CB-CD1 4.48Å; E334-I338 VanDerWaalsContact O-CB 3.29Å; E334-I338 WeakPolarHBondContact O-CB 3.34Å; E334-I338 WeakPolarHBondContact O-CD1 3.24Å; E334-I338 WeakPolarHBondContact O-CG1 3.48Å; E334-I338 PolarHBondContact O-N 2.7Å; A336-I338 PolarHBondContact O-N 3.19Å; I338-E340 VanDerWaalsContact C-N 3.33Å; I338-E340 PolarHBondContact O-N 2.95Å; I338-I341 PolarHBondContact O-N 3.17Å; I338-L342 HydrophobicContact CG2-CD1 3.56Å; I338-L342 HydrophobicContact CG2-CG 4.23Å; I338-L342 VanDerWaalsContact O-CB 3.3Å; I338-L342 WeakPolarHBondContact O-CB 3.46Å; I338-L342 WeakPolarHBondContact O-CD1 3.42Å; I338-L342 VanDerWaalsContact O-CG 3.22Å; I338-L342 WeakPolarHBondContact O-CG 3.45Å; I338-L342 PolarHBondContact O-N 3.2Å; I338-P360 HydrophobicContact CG2-CB 4.19Å; I338-F363 HydrophobicContact CB-CD2 4.34Å; I338-F363 HydrophobicContact CD1-CE2 4.5Å; I338-F363 HydrophobicContact CG2-CD2 3.6Å; I338-F363 HydrophobicContact CG2-CE2 4Å
339A90.1Very high89.8Confident17 Ų1741.1 Ų41.114%0.1421%0.213CC..Hα-helixtrans-64.5-37-179.500000112.6T335 A336 A337 K343 F363T335-A339 WeakPolarHBondContact O-CB 3.35Å; T335-A339 PolarHBondContact O-N 3.42Å; A336-A339 PolarHBondContact O-N 2.86Å; A337-A339 VanDerWaalsContact C-N 3.34Å; A337-A339 PolarHBondContact O-N 3.18Å; A339-K343 WeakPolarHBondContact O-CD 3.43Å; A339-K343 VanDerWaalsContact O-CG 3.23Å; A339-K343 WeakPolarHBondContact O-CG 3.39Å; A339-K343 PolarHBondContact O-N 3.44Å; A339-F363 HydrophobicContact CB-CB 3.97Å
340E90.5Very high90.2Very high127 Ų12737.5 Ų37.559%0.59320%0.196SC*.Hα-helixtrans-68.9-48.3175.6-177.2172-158.200112A336 A337 I338 L342 K343 S344A336-E340 PolarHBondContact O-N 3.27Å; A336-E340 VanDerWaalsContact O-N 3.09Å; A337-E340 PolarHBondContact O-N 3.42Å; I338-E340 VanDerWaalsContact C-N 3.33Å; I338-E340 PolarHBondContact O-N 2.95Å; E340-L342 VanDerWaalsContact C-N 3.32Å; E340-L342 PolarHBondContact O-N 2.85Å; E340-K343 PolarHBondContact O-N 3.46Å; E340-S344 PolarHBondContact O-N 2.89Å; E340-S344 PolarHBondContact O-OG 3.18Å
341I91.6Very high90.5Very high17 Ų1738.1 Ų38.19%0.08720%0.2CC..Hα-helixtrans-59.5-42.3176.4-68.9162.5000111.2L263 L280 I283 L284 A337 I338 S344 A345L263-I341 HydrophobicContact CD1-CG2 3.88Å; L263-I341 HydrophobicContact CD2-CG2 3.93Å; L280-I341 HydrophobicContact CD1-CG2 4.04Å; I283-I341 HydrophobicContact CB-CG2 4.47Å; I283-I341 HydrophobicContact CG2-CD1 3.97Å; I283-I341 HydrophobicContact CG2-CG1 4.05Å; I283-I341 HydrophobicContact CG2-CG2 3.78Å; L284-I341 HydrophobicContact CB-CD1 4.49Å; L284-I341 HydrophobicContact CD2-CD1 3.52Å; L284-I341 HydrophobicContact CG-CD1 3.82Å; A337-I341 WeakPolarHBondContact O-CB 3.29Å; A337-I341 WeakPolarHBondContact O-CD1 3.36Å; A337-I341 VanDerWaalsContact O-CG1 3.28Å; A337-I341 WeakPolarHBondContact O-CG1 3.35Å; A337-I341 PolarHBondContact O-N 3.35Å; I338-I341 PolarHBondContact O-N 3.17Å; I341-S344 PolarHBondContact O-N 3.43Å; I341-S344 PolarHBondContact O-OG 3.07Å; I341-S344 VanDerWaalsContact O-OG 3.05Å; I341-A345 PolarHBondContact O-N 3.43Å
342L92.6Very high91Very high0 Ų034.2 Ų34.20%019%0.186CC..Hα-helixtrans-62-42.3176.4-79.6165.3000112.6L263 L265 I338 E340 V348 P360 L361 F363 L364L263-L342 HydrophobicContact CD2-CD2 3.7Å; L263-L342 HydrophobicContact CD2-CG 4.16Å; L265-L342 HydrophobicContact CD1-CD2 4.36Å; L265-L342 HydrophobicContact CD2-CD2 4.09Å; I338-L342 HydrophobicContact CG2-CD1 3.56Å; I338-L342 HydrophobicContact CG2-CG 4.23Å; I338-L342 VanDerWaalsContact O-CB 3.3Å; I338-L342 WeakPolarHBondContact O-CB 3.46Å; I338-L342 WeakPolarHBondContact O-CD1 3.42Å; I338-L342 VanDerWaalsContact O-CG 3.22Å; I338-L342 WeakPolarHBondContact O-CG 3.45Å; I338-L342 PolarHBondContact O-N 3.2Å; E340-L342 VanDerWaalsContact C-N 3.32Å; E340-L342 PolarHBondContact O-N 2.85Å; L342-V348 HydrophobicContact CD2-CG1 4.38Å; L342-P360 HydrophobicContact CD1-CB 4.07Å; L342-P360 WeakPolarHBondContact CD1-O 3.43Å; L342-L361 HydrophobicContact CD2-CD2 4.07Å; L342-F363 HydrophobicContact CD1-CB 4.28Å; L342-F363 HydrophobicContact CD1-CD2 4.48Å; L342-L364 HydrophobicContact CB-CD1 3.99Å; L342-L364 HydrophobicContact CB-CD2 3.83Å; L342-L364 HydrophobicContact CB-CG 3.92Å; L342-L364 HydrophobicContact CD1-CD1 4.46Å; L342-L364 HydrophobicContact CD1-CG 4.26Å; L342-L364 HydrophobicContact CD2-CD1 4.07Å; L342-L364 HydrophobicContact CG-CD1 4.43Å
343K92.2Very high91.1Very high121 Ų12130.9 Ų30.953%0.52617%0.169SC..Hα-helixtrans-70.8-31179.3-72.9169.5-176.4178.90113.1A339 E340 L364A339-K343 WeakPolarHBondContact O-CD 3.43Å; A339-K343 VanDerWaalsContact O-CG 3.23Å; A339-K343 WeakPolarHBondContact O-CG 3.39Å; A339-K343 PolarHBondContact O-N 3.44Å; E340-K343 PolarHBondContact O-N 3.46Å; K343-L364 HydrophobicContact CG-CD2 3.74Å
344S91.3Very high91.2Very high69 Ų6927.2 Ų27.248%0.48316%0.16SC..Hα-helixtrans-79.8-22-177.771.20000113.6E340 I341E340-S344 PolarHBondContact O-N 2.89Å; E340-S344 PolarHBondContact O-OG 3.18Å; I341-S344 PolarHBondContact O-N 3.43Å; I341-S344 PolarHBondContact O-OG 3.07Å; I341-S344 VanDerWaalsContact O-OG 3.05Å
345A93.9Very high91.5Very high7 Ų727.1 Ų27.16%0.05816%0.16CC..  trans-68.2143.917400000111.8K237 L263 I341 V348K237-A345 PolarHBondContact NZ-O 3.37Å; L263-A345 HydrophobicContact CB-CB 3.7Å; L263-A345 HydrophobicContact CD2-CB 4.12Å; I341-A345 PolarHBondContact O-N 3.43Å; A345-V348 HydrophobicContact CB-CG2 4.07Å
346D93.5Very high91.5Very high36 Ų3625.1 Ų25.119%0.19315%0.148CC..SBendtrans-94.7-32.1174.2-61-41.8000111V232 K237 V238 K261V232-D346 HydrophobicContact CG1-CB 3.87Å; V232-D346 HydrophobicContact CG2-CB 4.16Å; K237-D346 IonicContact NZ-OD1 3.63Å; K237-D346 PolarHBondContact NZ-OD1 2.97Å; V238-D346 PolarHBondContact N-O 2.92Å; V238-D346 VanDerWaalsContact N-O 3.14Å; K261-D346 HydrophobicContact CB-CB 4.29Å; K261-D346 WeakPolarHBondContact CB-OD2 3.33Å; K261-D346 WeakPolarHBondContact CD-OD2 3.41Å; K261-D346 WeakPolarHBondContact CG-OD2 3.31Å; K261-D346 PolarHBondContact O-N 3.24Å
347V96.9Very high91.1Very high0 Ų026.1 Ų26.10%015%0.145CC..EExtended strand (participates in β ladder)trans-127.8122.5175.1-168.40000110I228 V232 V238 C240 L255 K261 V262 L263 L349I228-V347 HydrophobicContact CG2-CG1 4.09Å; I228-V347 HydrophobicContact CG2-CG2 3.61Å; V232-V347 HydrophobicContact CG2-CG2 3.6Å; V238-V347 HydrophobicContact CB-CG1 4.38Å; V238-V347 WeakPolarHBondContact O-CA 3.4Å; C240-V347 HydrophobicContact CB-CG1 4.32Å; C240-V347 WeakPolarHBondContact SG-CG1 3.22Å; L255-V347 HydrophobicContact CD1-CG1 4.13Å; K261-V347 PolarHBondContact O-N 2.93Å; V262-V347 WeakPolarHBondContact CA-O 3.33Å; V262-V347 HydrophobicContact CG1-CB 4.35Å; L263-V347 PolarHBondContact N-O 3.43Å; V347-L349 HydrophobicContact CB-CD1 4.2Å; V347-L349 HydrophobicContact CG1-CD1 3.75Å; V347-L349 HydrophobicContact CG1-CG 4.01Å
348V96.8Very high90.7Very high1 Ų129.5 Ų29.51%0.00616%0.163CC..EExtended strand (participates in β ladder)trans-105.5126173.9-176.50000109V238 L239 C240 L263 L265 L342 A345 L361 F369V238-V348 PolarHBondContact O-N 3.45Å; L239-V348 WeakPolarHBondContact CA-O 3.26Å; L239-V348 HydrophobicContact CD1-CB 4.41Å; L239-V348 HydrophobicContact CD1-CG1 4.42Å; C240-V348 PolarHBondContact N-O 3.45Å; L263-V348 HydrophobicContact CD2-CG2 4.4Å; L263-V348 WeakPolarHBondContact O-CA 3.49Å; L265-V348 HydrophobicContact CD1-CG1 3.56Å; L265-V348 HydrophobicContact CD2-CG1 4.31Å; L265-V348 HydrophobicContact CG-CG1 3.68Å; L342-V348 HydrophobicContact CD2-CG1 4.38Å; A345-V348 HydrophobicContact CB-CG2 4.07Å; V348-L361 HydrophobicContact CG1-CD2 4.04Å; V348-F369 HydrophobicContact CB-CE1 3.89Å; V348-F369 HydrophobicContact CB-CZ 3.95Å; V348-F369 HydrophobicContact CG1-CZ 4.46Å; V348-F369 HydrophobicContact CG2-CE1 3.79Å; V348-F369 HydrophobicContact CG2-CZ 3.91Å
349L95.9Very high90.3Very high0 Ų030.2 Ų30.20%017%0.17CC..EExtended strand (participates in β ladder)trans-117.6126.4-171.8-65.3108.4000111.3C240 V248 L251 V252 L255 V262 L263 R264 L265 V347C240-L349 HydrophobicContact CB-CD2 3.84Å; C240-L349 HydrophobicContact CB-CG 3.96Å; C240-L349 WeakPolarHBondContact O-CA 3.43Å; V248-L349 HydrophobicContact CG1-CB 3.89Å; L251-L349 HydrophobicContact CB-CD2 3.74Å; V252-L349 HydrophobicContact CG2-CB 3.86Å; V252-L349 HydrophobicContact CG2-CD1 4.12Å; V252-L349 HydrophobicContact CG2-CD2 3.83Å; V252-L349 HydrophobicContact CG2-CG 4.13Å; L255-L349 HydrophobicContact CD1-CD1 4.35Å; L255-L349 HydrophobicContact CD1-CD2 3.84Å; V262-L349 HydrophobicContact CB-CD1 3.78Å; V262-L349 HydrophobicContact CG1-CD1 3.93Å; L263-L349 PolarHBondContact O-N 2.98Å; R264-L349 CarbonylContact C-O 3.6Å; R264-L349 WeakPolarHBondContact CA-O 3.39Å; R264-L349 WeakPolarHBondContact CD-O 3.46Å; L265-L349 PolarHBondContact N-O 3.34Å; V347-L349 HydrophobicContact CB-CD1 4.2Å; V347-L349 HydrophobicContact CG1-CD1 3.75Å; V347-L349 HydrophobicContact CG1-CG 4.01Å
350S93.9Very high90.1Very high0 Ų030.3 Ų30.30%017%0.169CC..EExtended strand (participates in β ladder)trans-151173177.882.40000112.3C240 C241 A242 V248 A355C240-S350 PolarHBondContact O-N 3.18Å; C241-S350 VanDerWaalsContact CA-O 3.27Å; C241-S350 WeakPolarHBondContact CA-O 3.42Å; A242-S350 PolarHBondContact N-O 2.91Å; V248-S350 WeakPolarHBondContact CG2-O 3.38Å; S350-A355 PolarHBondContact OG-N 3.19Å
351T92.1Very high90.1Very high13 Ų1324.2 Ų24.28%0.0814%0.141CC..EExtended strand (participates in β ladder)trans-7515716556.40000109.9A242 N245 V248 T353 G354 A355A242-T351 CarbonylContact O-C 3.59Å; A242-T351 WeakPolarHBondContact O-CA 3.41Å; N245-T351 WeakPolarHBondContact OD1-CG2 3.26Å; V248-T351 HydrophobicContact CG2-CG2 4.06Å; T351-T353 PolarHBondContact O-N 3.31Å; T351-T353 VanDerWaalsContact O-N 3.08Å; T351-T353 PolarHBondContact OG1-OG1 2.95Å; T351-G354 VanDerWaalsContact O-CA 3.3Å; T351-G354 WeakPolarHBondContact O-CA 3.29Å; T351-G354 PolarHBondContact O-N 3.49Å; T351-G354 PolarHBondContact OG1-N 3.33Å; T351-A355 PolarHBondContact O-N 3.34Å
352N93.1Very high90Very high2 Ų228.5 Ų28.51%0.01116%0.159CC..THydrogen-bonded Turntrans-46.8-45175.8-67.49.2000112.1C241 A242 G354 A380 S384 I387C241-N352 WeakPolarHBondContact CB-OD1 3.35Å; A242-N352 WeakPolarHBondContact CA-OD1 3.17Å; A242-N352 PolarHBondContact N-OD1 3.33Å; A242-N352 PolarHBondContact O-N 3.01Å; A242-N352 PolarHBondContact O-OD1 2.82Å; N352-G354 VanDerWaalsContact C-N 3.33Å; N352-G354 PolarHBondContact O-N 3.05Å; N352-A380 WeakPolarHBondContact ND2-CB 3.34Å; N352-S384 PolarHBondContact ND2-OG 2.83Å; N352-S384 VanDerWaalsContact ND2-OG 3.12Å; N352-I387 WeakPolarHBondContact O-CB 3.45Å; N352-I387 VanDerWaalsContact O-CG2 3.29Å; N352-I387 WeakPolarHBondContact O-CG2 3.26Å
353T88.8Confident89.9Confident32 Ų3230.8 Ų30.820%0.19617%0.169CC..THydrogen-bonded Turntrans-72.8-20.4176.854.20000114.4T144 R147 T351 I387T144-T353 HydrophobicContact CG2-CG2 3.86Å; R147-T353 VanDerWaalsContact CD-O 3.28Å; R147-T353 WeakPolarHBondContact CD-O 3.33Å; R147-T353 PolarHBondContact NH1-O 3.24Å; T351-T353 PolarHBondContact O-N 3.31Å; T351-T353 VanDerWaalsContact O-N 3.08Å; T351-T353 PolarHBondContact OG1-OG1 2.95Å; T353-I387 HydrophobicContact CG2-CD1 4.33Å
354G86.9Confident89.8Confident17 Ų1725.5 Ų25.518%0.17515%0.146CC..THydrogen-bonded Turntrans-78.3-27176.900000113.4T351 N352 C356T351-G354 VanDerWaalsContact O-CA 3.3Å; T351-G354 WeakPolarHBondContact O-CA 3.29Å; T351-G354 PolarHBondContact O-N 3.49Å; T351-G354 PolarHBondContact OG1-N 3.33Å; N352-G354 VanDerWaalsContact C-N 3.33Å; N352-G354 PolarHBondContact O-N 3.05Å; G354-C356 PolarHBondContact O-N 3.21Å
355A90Very high89.7Confident0 Ų025.8 Ų25.80%015%0.147CC..SBendtrans-72.218.5177.600000114.8L239 S350 T351 L361 I387 A388L239-A355 HydrophobicContact CD2-CB 4.39Å; S350-A355 PolarHBondContact OG-N 3.19Å; T351-A355 PolarHBondContact O-N 3.34Å; A355-L361 HydrophobicContact CB-CD1 3.91Å; A355-I387 HydrophobicContact CB-CG2 4.34Å; A355-A388 HydrophobicContact CB-CB 4.23Å
356C85.6Confident89.2Confident6 Ų628.5 Ų28.54%0.04117%0.169CC..  trans-80.6154.4-171.168.40000114.3R147 G354 D358 G359 I387R147-C356 HydrophobicContact CG-CB 4.07Å; R147-C356 PolarHBondContact NE-SG 3.49Å; R147-C356 VanDerWaalsContact NE-SG 3.4Å; G354-C356 PolarHBondContact O-N 3.21Å; C356-D358 PolarHBondContact O-N 3.38Å; C356-D358 VanDerWaalsContact O-N 3.12Å; C356-G359 WeakPolarHBondContact O-CA 3.42Å; C356-G359 PolarHBondContact O-N 3.35Å; C356-I387 HydrophobicContact CB-CG2 4Å
357D80.1Confident88.9Confident81 Ų8133.9 Ų33.943%0.43319%0.193SC..THydrogen-bonded Turntrans-67.3-10.2-177-56.3-25.5000115.6K362 R391D357-K362 WeakPolarHBondContact O-CB 3.35Å; D357-R391 IonicContact OD1-CZ 3.72Å; D357-R391 VanDerWaalsContact OD1-CZ 3.25Å; D357-R391 IonicContact OD1-NE 3.33Å; D357-R391 PolarHBondContact OD1-NE 3Å; D357-R391 IonicContact OD1-NH2 2.86Å; D357-R391 PolarHBondContact OD1-NH2 3.44Å
358D79Confident88.7Confident73 Ų7335.3 Ų35.339%0.3920%0.2SC..THydrogen-bonded Turntrans-86-17168.7-42.6-75.1000113R150 C356 K362R150-D358 IonicContact CZ-OD1 2.83Å; R150-D358 IonicContact CZ-OD2 3.45Å; R150-D358 IonicContact NH1-OD1 2.8Å; R150-D358 PolarHBondContact NH1-OD1 2.85Å; R150-D358 IonicContact NH1-OD2 3.57Å; R150-D358 PolarHBondContact NH1-OD2 2.72Å; R150-D358 IonicContact NH2-OD1 2.74Å; R150-D358 IonicContact NH2-OD2 2.79Å; R150-D358 PolarHBondContact NH2-OD2 2.84Å; C356-D358 PolarHBondContact O-N 3.38Å; C356-D358 VanDerWaalsContact O-N 3.12Å; D358-K362 PolarHBondContact O-NZ 2.87Å
359G82.4Confident88.7Confident15 Ų1535.5 Ų35.516%0.15520%0.2CC..SBendtrans-82.1-163.3-172.900000113.1C356 L361 K362C356-G359 WeakPolarHBondContact O-CA 3.42Å; C356-G359 PolarHBondContact O-N 3.35Å; G359-L361 PolarHBondContact O-N 3.11Å; G359-K362 WeakPolarHBondContact O-CD 3.28Å; G359-K362 VanDerWaalsContact O-CG 3.24Å; G359-K362 WeakPolarHBondContact O-CG 3.4Å; G359-K362 PolarHBondContact O-N 2.99Å
360P85.1Confident88.7Confident19 Ų1937 Ų3712%0.12321%0.208CC..G310 helixtrans-58.8-32.8178.8-2434.4000113.4L265 L280 I338 L342 K362 F363L265-P360 HydrophobicContact CD1-CB 4.21Å; L265-P360 HydrophobicContact CD1-CG 4.39Å; L265-P360 HydrophobicContact CD2-CB 4.16Å; L265-P360 HydrophobicContact CD2-CG 4.27Å; L280-P360 HydrophobicContact CD2-CB 4.06Å; L280-P360 HydrophobicContact CD2-CG 3.84Å; I338-P360 HydrophobicContact CG2-CB 4.19Å; L342-P360 HydrophobicContact CD1-CB 4.07Å; L342-P360 WeakPolarHBondContact CD1-O 3.43Å; P360-K362 PolarHBondContact O-N 3.49Å; P360-F363 WeakPolarHBondContact O-CD2 3.5Å; P360-F363 PolarHBondContact O-N 3.31Å; P360-F363 VanDerWaalsContact O-N 3.1Å
361L90.6Very high88.8Confident0 Ų037.5 Ų37.50%021%0.21CC..G310 helixtrans-64.4-7-177.9-60.4-171000115L239 L265 L342 V348 A355 G359 F363 L364 F369 R391L239-L361 HydrophobicContact CD1-CD1 4.06Å; L239-L361 HydrophobicContact CD2-CD1 3.98Å; L265-L361 HydrophobicContact CD1-CD2 3.52Å; L265-L361 HydrophobicContact CD1-CG 3.85Å; L342-L361 HydrophobicContact CD2-CD2 4.07Å; V348-L361 HydrophobicContact CG1-CD2 4.04Å; A355-L361 HydrophobicContact CB-CD1 3.91Å; G359-L361 PolarHBondContact O-N 3.11Å; L361-F363 VanDerWaalsContact C-N 3.26Å; L361-L364 HydrophobicContact CD2-CD1 4.02Å; L361-F369 HydrophobicContact CD1-CE2 4.42Å; L361-F369 HydrophobicContact CD2-CE2 3.97Å; L361-F369 HydrophobicContact CD2-CZ 3.91Å; L361-R391 PolarHBondContact O-NH1 2.81Å; L361-R391 PolarHBondContact O-NH2 3.26Å
362K89.7Confident89.1Confident106 Ų10636.9 Ų36.946%0.46121%0.206SC..G310 helixtrans-73.3-17.2172.481.9-167.4166.1-164.70114D357 D358 G359 P360 L364D357-K362 WeakPolarHBondContact O-CB 3.35Å; D358-K362 PolarHBondContact O-NZ 2.87Å; G359-K362 WeakPolarHBondContact O-CD 3.28Å; G359-K362 VanDerWaalsContact O-CG 3.24Å; G359-K362 WeakPolarHBondContact O-CG 3.4Å; G359-K362 PolarHBondContact O-N 2.99Å; P360-K362 PolarHBondContact O-N 3.49Å; K362-L364 VanDerWaalsContact C-N 3.27Å
363F89.3Confident89.4Confident48 Ų4836.9 Ų36.921%0.21121%0.206CC..G310 helixtrans-87.3-0178.2-52.7-55.1000112.8T335 I338 A339 L342 P360 L361T335-F363 HydrophobicContact CG2-CD1 3.61Å; T335-F363 HydrophobicContact CG2-CE1 3.33Å; T335-F363 HydrophobicContact CG2-CG 4.33Å; T335-F363 HydrophobicContact CG2-CZ 3.85Å; I338-F363 HydrophobicContact CB-CD2 4.34Å; I338-F363 HydrophobicContact CD1-CE2 4.5Å; I338-F363 HydrophobicContact CG2-CD2 3.6Å; I338-F363 HydrophobicContact CG2-CE2 4Å; A339-F363 HydrophobicContact CB-CB 3.97Å; L342-F363 HydrophobicContact CD1-CB 4.28Å; L342-F363 HydrophobicContact CD1-CD2 4.48Å; P360-F363 WeakPolarHBondContact O-CD2 3.5Å; P360-F363 PolarHBondContact O-N 3.31Å; P360-F363 VanDerWaalsContact O-N 3.1Å; L361-F363 VanDerWaalsContact C-N 3.26Å
364L90.4Very high89.8Confident10 Ų1035.3 Ų35.35%0.05220%0.197CC..SBendtrans-104.4147.8173-70.7172.2000110.4L342 K343 L361 K362 H368 F369L342-L364 HydrophobicContact CB-CD1 3.99Å; L342-L364 HydrophobicContact CB-CD2 3.83Å; L342-L364 HydrophobicContact CB-CG 3.92Å; L342-L364 HydrophobicContact CD1-CD1 4.46Å; L342-L364 HydrophobicContact CD1-CG 4.26Å; L342-L364 HydrophobicContact CD2-CD1 4.07Å; L342-L364 HydrophobicContact CG-CD1 4.43Å; K343-L364 HydrophobicContact CG-CD2 3.74Å; L361-L364 HydrophobicContact CD2-CD1 4.02Å; K362-L364 VanDerWaalsContact C-N 3.27Å; L364-H368 HydrophobicContact CB-CB 4.09Å; L364-F369 HydrophobicContact CD1-CE2 3.82Å; L364-F369 HydrophobicContact CD1-CZ 3.68Å
365P89Confident90.3Very high76 Ų7634.6 Ų34.649%0.49419%0.189SC..  trans-64.1157.1171.927.8-32.4000111.2E367 H368P365-E367 PolarHBondContact O-N 3.16Å; P365-H368 HydrophobicContact CG-CB 4.01Å; P365-H368 VanDerWaalsContact O-CB 3.29Å; P365-H368 WeakPolarHBondContact O-CB 3.3Å; P365-H368 PolarHBondContact O-N 3.44Å; P365-H368 VanDerWaalsContact O-N 3.14Å
366A84.2Confident90.5Very high64 Ų6436.1 Ų36.153%0.52920%0.196SC..THydrogen-bonded Turntrans-60.5-32-176.300000113.4
367E87.1Confident91.1Very high148 Ų14835.8 Ų35.869%0.69219%0.194SC*.THydrogen-bonded Turntrans-94.518.1-178.8-62174.7174.500112.9P162 P365 F369P162-E367 HydrophobicContact CB-CG 4.36Å; P162-E367 HydrophobicContact CG-CG 4.09Å; P365-E367 PolarHBondContact O-N 3.16Å; E367-F369 PolarHBondContact O-N 3.07Å
368H93.2Very high91.8Very high31 Ų3132.1 Ų32.114%0.14418%0.175CC..  trans-68.4-32.6-177-17566.2000114.3K237 L364 P365K237-H368 VanDerWaalsContact CB-O 3.29Å; K237-H368 WeakPolarHBondContact CB-O 3.5Å; L364-H368 HydrophobicContact CB-CB 4.09Å; P365-H368 HydrophobicContact CG-CB 4.01Å; P365-H368 VanDerWaalsContact O-CB 3.29Å; P365-H368 WeakPolarHBondContact O-CB 3.3Å; P365-H368 PolarHBondContact O-N 3.44Å; P365-H368 VanDerWaalsContact O-N 3.14Å
369F96.1Very high92.5Very high4 Ų430.9 Ų30.92%0.01817%0.167CC..  trans-102.9127.7-177.7-62.4-72.8000110.2K237 L239 V348 L361 L364 E367 R391 A392K237-F369 HydrophobicContact CB-CD1 4.39Å; L239-F369 HydrophobicContact CB-CB 4.32Å; L239-F369 HydrophobicContact CB-CD1 3.71Å; L239-F369 HydrophobicContact CB-CD2 4.1Å; L239-F369 HydrophobicContact CB-CE1 3.94Å; L239-F369 HydrophobicContact CB-CE2 4.31Å; L239-F369 HydrophobicContact CB-CG 3.78Å; L239-F369 HydrophobicContact CB-CZ 4.24Å; L239-F369 HydrophobicContact CD1-CZ 4.37Å; L239-F369 HydrophobicContact CD2-CD2 4.16Å; L239-F369 HydrophobicContact CD2-CE2 4.2Å; V348-F369 HydrophobicContact CB-CE1 3.89Å; V348-F369 HydrophobicContact CB-CZ 3.95Å; V348-F369 HydrophobicContact CG1-CZ 4.46Å; V348-F369 HydrophobicContact CG2-CE1 3.79Å; V348-F369 HydrophobicContact CG2-CZ 3.91Å; L361-F369 HydrophobicContact CD1-CE2 4.42Å; L361-F369 HydrophobicContact CD2-CE2 3.97Å; L361-F369 HydrophobicContact CD2-CZ 3.91Å; L364-F369 HydrophobicContact CD1-CE2 3.82Å; L364-F369 HydrophobicContact CD1-CZ 3.68Å; E367-F369 PolarHBondContact O-N 3.07Å; F369-R391 HydrophobicContact CD2-CB 4.33Å; F369-A392 HydrophobicContact CB-CB 4.44Å; F369-A392 WeakPolarHBondContact O-CA 3.37Å
370D95.6Very high93Very high31 Ų3130.2 Ų30.217%0.16616%0.16CC..SBendtrans-76.8-45173-58.7-77.9000110.4Q236 K237 R393 K394Q236-D370 WeakPolarHBondContact CA-OD2 3.15Å; Q236-D370 HydrophobicContact CB-CB 4.09Å; Q236-D370 VanDerWaalsContact OE1-CB 3.25Å; Q236-D370 VanDerWaalsContact OE1-CG 3.29Å; Q236-D370 PolarHBondContact OE1-OD1 3.31Å; K237-D370 PolarHBondContact N-OD2 3.31Å; K237-D370 PolarHBondContact O-N 3.03Å; D370-R393 WeakPolarHBondContact O-CG 3.42Å; D370-R393 PolarHBondContact O-N 3.1Å; D370-R393 IonicContact OD1-CZ 2.86Å; D370-R393 VanDerWaalsContact OD1-CZ 3.31Å; D370-R393 IonicContact OD1-NE 2.78Å; D370-R393 IonicContact OD1-NH2 2.71Å; D370-R393 PolarHBondContact OD1-NH2 3.47Å; D370-K394 PolarHBondContact O-N 3.15Å
371W97Very high93.5Very high12 Ų1230.8 Ų30.85%0.04516%0.161CC..EExtended strand (participates in β ladder)trans-126.1137.2-168.5-63.920.7000110.8L204 I227 A231 Q236 K237 V238 L239 K394 I396L204-W371 HydrophobicContact CD2-CH2 3.52Å; L204-W371 HydrophobicContact CD2-CZ3 3.85Å; I227-W371 HydrophobicContact CG2-CZ3 4.17Å; A231-W371 HydrophobicContact CB-CD2 4.02Å; A231-W371 HydrophobicContact CB-CE3 3.57Å; A231-W371 HydrophobicContact CB-CH2 3.95Å; A231-W371 HydrophobicContact CB-CZ2 4.34Å; A231-W371 HydrophobicContact CB-CZ3 3.54Å; Q236-W371 HydrophobicContact CG-CZ2 4.46Å; K237-W371 PolarHBondContact O-N 3.12Å; V238-W371 HydrophobicContact CG1-CB 4.45Å; L239-W371 PolarHBondContact N-O 3.06Å; W371-K394 WeakPolarHBondContact CA-O 3.47Å; W371-K394 HydrophobicContact CD2-CD 3.99Å; W371-K394 HydrophobicContact CG-CB 4.34Å; W371-K394 HydrophobicContact CG-CD 4.27Å; W371-K394 HydrophobicContact CG-CG 4.5Å; W371-K394 HydrophobicContact CZ2-CD 4.11Å; W371-I396 HydrophobicContact CE3-CD1 3.52Å; W371-I396 HydrophobicContact CZ3-CD1 3.61Å
372V97.9Very high93.8Very high0 Ų031.5 Ų31.50%017%0.165CC..EExtended strand (participates in β ladder)trans-109.4126.1167.3161.20000109.6L239 I374 A388 L389 A392 K394 C395 I396L239-V372 HydrophobicContact CB-CG2 4Å; L239-V372 HydrophobicContact CD2-CG2 4.08Å; L239-V372 HydrophobicContact CG-CG2 4.28Å; L239-V372 WeakPolarHBondContact O-CA 3.45Å; V372-I374 HydrophobicContact CG1-CD1 4.18Å; V372-I374 HydrophobicContact CG1-CG1 3.82Å; V372-A388 HydrophobicContact CG1-CB 3.97Å; V372-A388 WeakPolarHBondContact CG2-O 3.5Å; V372-L389 HydrophobicContact CG1-CD2 4.13Å; V372-A392 HydrophobicContact CB-CB 4.05Å; V372-A392 HydrophobicContact CG2-CB 3.47Å; V372-A392 VanDerWaalsContact CG2-CB 3.47Å; V372-K394 PolarHBondContact N-O 3.19Å; V372-C395 CarbonylContact O-C 3.53Å; V372-C395 WeakPolarHBondContact O-CA 3.13Å; V372-I396 PolarHBondContact O-N 3.31Å
373V98.5Very high94.1Very high1 Ų126.5 Ų26.51%0.00614%0.143CC..EExtended strand (participates in β ladder)trans-111.2126175.3-177.10000108.3V224 I228 V238 L239 C240 C241 I396V224-V373 HydrophobicContact CG1-CG1 3.73Å; I228-V373 HydrophobicContact CD1-CG1 4.38Å; I228-V373 HydrophobicContact CG1-CG2 4.05Å; V238-V373 HydrophobicContact CG1-CG2 3.76Å; L239-V373 PolarHBondContact O-N 3.45Å; C240-V373 CarbonylContact C-O 3.6Å; C240-V373 WeakPolarHBondContact CA-O 3.27Å; C241-V373 PolarHBondContact N-O 2.98Å; V373-I396 CarbonylContact C-O 3.57Å; V373-I396 WeakPolarHBondContact CA-O 3.48Å; V373-I396 HydrophobicContact CG2-CB 4.3Å
374I98.2Very high94.4Very high0 Ų024.7 Ų24.70%014%0.137CC..EExtended strand (participates in β ladder)trans-117.7104.7176.5-52.3-176.1000108.9C241 V372 C377 C385 L389 I396 L397 A398C241-I374 HydrophobicContact CB-CG1 4.45Å; C241-I374 CarbonylContact O-C 3.48Å; C241-I374 WeakPolarHBondContact O-CA 3.41Å; V372-I374 HydrophobicContact CG1-CD1 4.18Å; V372-I374 HydrophobicContact CG1-CG1 3.82Å; I374-C377 HydrophobicContact CB-CB 4.26Å; I374-C377 HydrophobicContact CG2-CB 3.85Å; I374-C385 HydrophobicContact CD1-CB 3.77Å; I374-L389 HydrophobicContact CD1-CD1 4.48Å; I374-L389 HydrophobicContact CD1-CD2 4.06Å; I374-L389 HydrophobicContact CD1-CG 4.04Å; I374-I396 PolarHBondContact N-O 3.03Å; I374-L397 HydrophobicContact CB-CD2 4.04Å; I374-L397 HydrophobicContact CD1-CD2 4.1Å; I374-L397 HydrophobicContact CG1-CD2 4.19Å; I374-A398 PolarHBondContact O-N 3.31Å
375D97.1Very high94.7Very high2 Ų224.2 Ų24.21%0.01113%0.134CC..THydrogen-bonded Turntrans-85.7153.2172-163.111.6000110.9K220 T221 C241 A242 P243 L251 C377 A398K220-D375 WeakPolarHBondContact CE-OD1 3.49Å; T221-D375 PolarHBondContact OG1-OD2 3.47Å; C241-D375 PolarHBondContact O-N 3.14Å; A242-D375 WeakPolarHBondContact CA-O 3.45Å; A242-D375 WeakPolarHBondContact CB-O 3.29Å; P243-D375 VanDerWaalsContact CD-O 3.23Å; P243-D375 WeakPolarHBondContact CD-O 3.38Å; L251-D375 HydrophobicContact CD1-CB 3.91Å; D375-C377 PolarHBondContact O-N 2.65Å; D375-A398 CarbonylContact C-O 3.57Å
376E95.2Very high95Very high31 Ų3120.6 Ų20.615%0.14511%0.111CC..THydrogen-bonded Turntrans47.137.3-165.9-53.6-63-176.200113.9K220 P243 A247 A378 Q379 A398K220-E376 IonicContact NZ-OE1 2.69Å; K220-E376 PolarHBondContact NZ-OE1 3.17Å; K220-E376 IonicContact NZ-OE2 2.74Å; K220-E376 PolarHBondContact NZ-OE2 2.87Å; P243-E376 HydrophobicContact CG-CB 4.15Å; P243-E376 WeakPolarHBondContact CG-O 3.47Å; A247-E376 HydrophobicContact CB-CG 4.07Å; E376-A378 PolarHBondContact O-N 2.95Å; E376-Q379 HydrophobicContact CB-CB 4.42Å; E376-Q379 WeakPolarHBondContact O-CB 3.44Å; E376-Q379 PolarHBondContact O-N 3.2Å; E376-A398 PolarHBondContact N-O 3.03Å
377C96.9Very high95.5Very high0 Ų018 Ų180%09%0.088CC..G310 helixtrans-58.2-32.1-178.3-170.90000113I374 D375 Q379 A380 L397 A398 M423I374-C377 HydrophobicContact CB-CB 4.26Å; I374-C377 HydrophobicContact CG2-CB 3.85Å; D375-C377 PolarHBondContact O-N 2.65Å; C377-Q379 PolarHBondContact O-N 2.94Å; C377-A380 WeakPolarHBondContact O-CB 3.39Å; C377-A380 PolarHBondContact O-N 3.13Å; C377-L397 HydrophobicContact CB-CB 4.21Å; C377-A398 PolarHBondContact N-O 2.96Å; C377-M423 HydrophobicContact CB-CB 4.15Å; C377-M423 HydrophobicContact CB-SD 4.36Å
378A95Very high95.9Very high3 Ų311 Ų113%0.0256%0.055CC..G310 helixtrans-61.5-25.9173.900000114.1E376 D400 S421 M423E376-A378 PolarHBondContact O-N 2.95Å; A378-D400 WeakPolarHBondContact CB-O 3.47Å; A378-S421 WeakPolarHBondContact O-CB 3.4Å; A378-M423 HydrophobicContact CB-SD 3.99Å
379Q93.1Very high96Very high48 Ų489.5 Ų9.522%0.2245%0.048CC..G310 helixtrans-89.5-3.7176.6-156.8-165.50.900112.2P243 E376 C377P243-Q379 HydrophobicContact CG-CB 4.18Å; E376-Q379 HydrophobicContact CB-CB 4.42Å; E376-Q379 WeakPolarHBondContact O-CB 3.44Å; E376-Q379 PolarHBondContact O-N 3.2Å; C377-Q379 PolarHBondContact O-N 2.94Å
380A94.4Very high95.9Very high1 Ų110.1 Ų10.11%0.0085%0.051CC..SBendtrans-97.5134.1-177.200000112.1P243 N352 C377 E382 P406P243-A380 HydrophobicContact CB-CB 3.98Å; P243-A380 HydrophobicContact CG-CB 4.08Å; N352-A380 WeakPolarHBondContact ND2-CB 3.34Å; C377-A380 WeakPolarHBondContact O-CB 3.39Å; C377-A380 PolarHBondContact O-N 3.13Å; A380-E382 PolarHBondContact O-N 2.68Å; A380-P406 VanDerWaalsContact C-CG 3.44Å; A380-P406 WeakPolarHBondContact O-CG 3.25Å
381L94.9Very high95.7Very high31 Ų319.8 Ų9.816%0.1625%0.048CC..BIsolated β-bridgetrans-57.5133.1164.7-67.6174.2000108.9M148 S383 S384 C385 P406 I408 L418M148-L381 HydrophobicContact SD-CD1 4.3Å; L381-S383 PolarHBondContact O-N 2.91Å; L381-S384 WeakPolarHBondContact O-CA 3.35Å; L381-S384 WeakPolarHBondContact O-CB 3.25Å; L381-S384 PolarHBondContact O-N 3.32Å; L381-S384 PolarHBondContact O-OG 3Å; L381-C385 PolarHBondContact O-N 2.94Å; L381-P406 HydrophobicContact CD2-CB 3.59Å; L381-P406 HydrophobicContact CD2-CG 4.17Å; L381-P406 HydrophobicContact CG-CB 3.91Å; L381-I408 HydrophobicContact CD2-CD1 3.99Å; L381-I408 HydrophobicContact CD2-CG1 4.06Å; L381-L418 HydrophobicContact CD2-CD1 4.12Å; L381-L418 HydrophobicContact CD2-CG 3.98Å; L381-L418 WeakPolarHBondContact CD2-O 3.44Å
382E96.7Very high95.6Very high15 Ų159.2 Ų9.27%0.075%0.045CC..Hα-helixtrans-55.1-39.6-178.9175168.4171.500111.9F7 A380 S384 C385 W386 L422 R425F7-E382 HydrophobicContact CE2-CG 4.29Å; F7-E382 WeakPolarHBondContact CE2-OE1 3.47Å; F7-E382 HydrophobicContact CZ-CG 3.86Å; F7-E382 VanDerWaalsContact CZ-OE1 3.29Å; F7-E382 WeakPolarHBondContact CZ-OE1 3.3Å; A380-E382 PolarHBondContact O-N 2.68Å; E382-S384 PolarHBondContact O-N 3.37Å; E382-C385 WeakPolarHBondContact O-CB 3.32Å; E382-C385 PolarHBondContact O-N 3.34Å; E382-W386 PolarHBondContact O-N 3.34Å; E382-W386 PolarHBondContact OE1-NE1 2.99Å; E382-W386 VanDerWaalsContact OE1-NE1 3.12Å; E382-L422 HydrophobicContact CB-CB 4.11Å; E382-L422 HydrophobicContact CG-CB 3.93Å; E382-L422 HydrophobicContact CG-CD1 4.02Å; E382-L422 HydrophobicContact CG-CG 4.49Å; E382-R425 IonicContact OE1-CZ 3.65Å; E382-R425 IonicContact OE1-NE 3.77Å; E382-R425 PolarHBondContact OE1-NE 3.04Å; E382-R425 IonicContact OE1-NH2 3.83Å; E382-R425 PolarHBondContact OE1-NH2 2.75Å; E382-R425 IonicContact OE2-CZ 2.87Å; E382-R425 IonicContact OE2-NE 3.84Å; E382-R425 PolarHBondContact OE2-NE 3.27Å; E382-R425 IonicContact OE2-NH2 3.68Å
383S95.5Very high95.5Very high1 Ų115.4 Ų15.41%0.0077%0.069CC..Hα-helixtrans-60.1-23175.157.40000114.7M148 L381M148-S383 PolarHBondContact SD-OG 3.37Å; L381-S383 PolarHBondContact O-N 2.91Å
384S95.5Very high95.3Very high10 Ų1015.6 Ų15.67%0.077%0.07CC..Hα-helixtrans-80.8-36.317380.10000112.1N352 L381 E382 W386 I387N352-S384 PolarHBondContact ND2-OG 2.83Å; N352-S384 VanDerWaalsContact ND2-OG 3.12Å; L381-S384 WeakPolarHBondContact O-CA 3.35Å; L381-S384 WeakPolarHBondContact O-CB 3.25Å; L381-S384 PolarHBondContact O-N 3.32Å; L381-S384 PolarHBondContact O-OG 3Å; E382-S384 PolarHBondContact O-N 3.37Å; S384-W386 VanDerWaalsContact C-N 3.29Å; S384-W386 PolarHBondContact O-N 2.62Å; S384-I387 WeakPolarHBondContact O-CB 3.39Å; S384-I387 WeakPolarHBondContact O-CG1 3.4Å; S384-I387 PolarHBondContact O-N 2.74Å
385C97.1Very high95.3Very high0 Ų015.6 Ų15.60%07%0.07CC..Hα-helixtrans-63.1-38.3178.8-62.20000111.2I374 L381 E382 I387 A388 L389 L422I374-C385 HydrophobicContact CD1-CB 3.77Å; L381-C385 PolarHBondContact O-N 2.94Å; E382-C385 WeakPolarHBondContact O-CB 3.32Å; E382-C385 PolarHBondContact O-N 3.34Å; C385-I387 PolarHBondContact O-N 3.26Å; C385-A388 PolarHBondContact O-N 3.12Å; C385-L389 HydrophobicContact CB-CD1 3.89Å; C385-L389 WeakPolarHBondContact O-CG 3.44Å; C385-L389 PolarHBondContact O-N 3.45Å; C385-L422 HydrophobicContact CB-CD2 3.87Å
386W96.4Very high95.3Very high0 Ų015.6 Ų15.60%07%0.069CC..Hα-helixtrans-59-16.8176.3-73.9115.4000114.9F7 L155 I167 L170 F171 E382 S384 L389 L390F7-W386 AromaticContact CE1-NE1 3.75Å; F7-W386 AromaticContact CZ-NE1 3.77Å; L155-W386 HydrophobicContact CD1-CD2 4.27Å; L155-W386 HydrophobicContact CD1-CE3 3.81Å; L155-W386 HydrophobicContact CD1-CH2 4.13Å; L155-W386 HydrophobicContact CD1-CZ3 3.74Å; L155-W386 HydrophobicContact CD2-CD2 3.67Å; L155-W386 HydrophobicContact CD2-CE3 4.08Å; L155-W386 HydrophobicContact CD2-CG 3.91Å; L155-W386 HydrophobicContact CD2-CZ2 4.29Å; I167-W386 HydrophobicContact CG1-CH2 4.22Å; I167-W386 HydrophobicContact CG1-CZ3 3.9Å; L170-W386 HydrophobicContact CB-CH2 3.88Å; L170-W386 HydrophobicContact CB-CZ2 4.24Å; L170-W386 HydrophobicContact CD1-CH2 3.39Å; L170-W386 HydrophobicContact CD1-CZ2 4.08Å; L170-W386 HydrophobicContact CD1-CZ3 3.88Å; L170-W386 HydrophobicContact CG-CH2 4.29Å; F171-W386 HydrophobicContact CD2-CH2 4.32Å; F171-W386 HydrophobicContact CD2-CZ2 4.29Å; F171-W386 AromaticContact CE2-CH2 3.58Å; F171-W386 HydrophobicContact CE2-CH2 3.58Å; F171-W386 AromaticContact CE2-CZ2 3.3Å; F171-W386 HydrophobicContact CE2-CZ2 3.3Å; F171-W386 HydrophobicContact CZ-CH2 4.37Å; F171-W386 AromaticContact CZ-CZ2 3.65Å; F171-W386 HydrophobicContact CZ-CZ2 3.65Å; E382-W386 PolarHBondContact O-N 3.34Å; E382-W386 PolarHBondContact OE1-NE1 2.99Å; E382-W386 VanDerWaalsContact OE1-NE1 3.12Å; S384-W386 VanDerWaalsContact C-N 3.29Å; S384-W386 PolarHBondContact O-N 2.62Å; W386-L389 HydrophobicContact CD2-CD1 4.17Å; W386-L389 HydrophobicContact CE3-CB 3.94Å; W386-L389 HydrophobicContact CE3-CD1 4.05Å; W386-L389 HydrophobicContact CZ3-CB 4.21Å; W386-L389 HydrophobicContact CZ3-CD1 4.32Å; W386-L390 HydrophobicContact CE3-CD2 4.17Å; W386-L390 HydrophobicContact CE3-CG 4.39Å; W386-L390 HydrophobicContact CZ3-CD2 4.4Å; W386-L390 WeakPolarHBondContact O-CD1 3.48Å; W386-L390 WeakPolarHBondContact O-CG 3.38Å
387I94.6Very high95.5Very high9 Ų914.1 Ų14.15%0.0466%0.063CC..Hα-helixtrans-66.1-40.1172.2-57.1170.4000110.8R147 M148 A151 N352 T353 A355 C356 S384 C385R147-I387 HydrophobicContact CB-CD1 4.12Å; M148-I387 HydrophobicContact CG-CD1 4.14Å; A151-I387 HydrophobicContact CB-CB 4.39Å; A151-I387 HydrophobicContact CB-CG1 3.7Å; N352-I387 WeakPolarHBondContact O-CB 3.45Å; N352-I387 VanDerWaalsContact O-CG2 3.29Å; N352-I387 WeakPolarHBondContact O-CG2 3.26Å; T353-I387 HydrophobicContact CG2-CD1 4.33Å; A355-I387 HydrophobicContact CB-CG2 4.34Å; C356-I387 HydrophobicContact CB-CG2 4Å; S384-I387 WeakPolarHBondContact O-CB 3.39Å; S384-I387 WeakPolarHBondContact O-CG1 3.4Å; S384-I387 PolarHBondContact O-N 2.74Å; C385-I387 PolarHBondContact O-N 3.26Å
388A94.8Very high95.6Very high0 Ų014.1 Ų14.10%06%0.063CC..Hα-helixtrans-89.3-41.6-179.300000112.4L239 C241 A355 V372 C385 L390 R391L239-A388 HydrophobicContact CD2-CB 4.36Å; C241-A388 HydrophobicContact CB-CB 4.29Å; A355-A388 HydrophobicContact CB-CB 4.23Å; V372-A388 HydrophobicContact CG1-CB 3.97Å; V372-A388 WeakPolarHBondContact CG2-O 3.5Å; C385-A388 PolarHBondContact O-N 3.12Å; A388-L390 PolarHBondContact O-N 3.1Å; A388-L390 VanDerWaalsContact O-N 3.13Å; A388-R391 WeakPolarHBondContact O-CB 3.49Å; A388-R391 PolarHBondContact O-N 3.14Å
389L95.8Very high95.6Very high0 Ų014 Ų140%06%0.061CC..Hα-helixtrans-58.1-30.7-172.3-68.9166.1000114.3L166 L170 V372 I374 C385 W386 R391 C395 L397 L422L166-L389 HydrophobicContact CD2-CD2 4.43Å; L170-L389 HydrophobicContact CD1-CD1 4.21Å; V372-L389 HydrophobicContact CG1-CD2 4.13Å; I374-L389 HydrophobicContact CD1-CD1 4.48Å; I374-L389 HydrophobicContact CD1-CD2 4.06Å; I374-L389 HydrophobicContact CD1-CG 4.04Å; C385-L389 HydrophobicContact CB-CD1 3.89Å; C385-L389 WeakPolarHBondContact O-CG 3.44Å; C385-L389 PolarHBondContact O-N 3.45Å; W386-L389 HydrophobicContact CD2-CD1 4.17Å; W386-L389 HydrophobicContact CE3-CB 3.94Å; W386-L389 HydrophobicContact CE3-CD1 4.05Å; W386-L389 HydrophobicContact CZ3-CB 4.21Å; W386-L389 HydrophobicContact CZ3-CD1 4.32Å; L389-R391 PolarHBondContact O-N 3.37Å; L389-C395 HydrophobicContact CD2-CB 3.34Å; L389-L397 HydrophobicContact CD2-CD2 4.49Å; L389-L422 HydrophobicContact CD1-CD2 3.44Å; L389-L422 VanDerWaalsContact CD1-CD2 3.44Å
390L93.5Very high95.8Very high17 Ų1711.8 Ų11.89%0.0895%0.051CC..THydrogen-bonded Turntrans-70.4-7.9180-63.9174.6000114.1V154 L155 Y158 I167 W386 A388V154-L390 HydrophobicContact CB-CD1 4.26Å; V154-L390 HydrophobicContact CG1-CD1 3.96Å; L155-L390 HydrophobicContact CB-CD1 4.34Å; L155-L390 HydrophobicContact CD1-CD2 3.99Å; Y158-L390 HydrophobicContact CD2-CD2 3.87Å; Y158-L390 HydrophobicContact CE2-CB 4.34Å; Y158-L390 HydrophobicContact CE2-CD2 3.98Å; Y158-L390 HydrophobicContact CG-CD2 4.39Å; Y158-L390 PolarHBondContact OH-O 2.95Å; I167-L390 HydrophobicContact CD1-CD2 3.88Å; I167-L390 HydrophobicContact CG1-CD2 4.5Å; W386-L390 HydrophobicContact CE3-CD2 4.17Å; W386-L390 HydrophobicContact CE3-CG 4.39Å; W386-L390 HydrophobicContact CZ3-CD2 4.4Å; W386-L390 WeakPolarHBondContact O-CD1 3.48Å; W386-L390 WeakPolarHBondContact O-CG 3.38Å; A388-L390 PolarHBondContact O-N 3.1Å; A388-L390 VanDerWaalsContact O-N 3.13Å
391R92.5Very high95.8Very high24 Ų2413.3 Ų13.39%0.0916%0.057CC..THydrogen-bonded Turntrans-94-3.5-177.7-64.4-58.5-160.2117.70.3114.8L239 D357 L361 F369 A388 L389L239-R391 HydrophobicContact CD2-CB 4.15Å; L239-R391 HydrophobicContact CD2-CG 4.38Å; D357-R391 IonicContact OD1-CZ 3.72Å; D357-R391 VanDerWaalsContact OD1-CZ 3.25Å; D357-R391 IonicContact OD1-NE 3.33Å; D357-R391 PolarHBondContact OD1-NE 3Å; D357-R391 IonicContact OD1-NH2 2.86Å; D357-R391 PolarHBondContact OD1-NH2 3.44Å; L361-R391 PolarHBondContact O-NH1 2.81Å; L361-R391 PolarHBondContact O-NH2 3.26Å; F369-R391 HydrophobicContact CD2-CB 4.33Å; A388-R391 WeakPolarHBondContact O-CB 3.49Å; A388-R391 PolarHBondContact O-N 3.14Å; L389-R391 PolarHBondContact O-N 3.37Å
392A94.6Very high95.8Very high0 Ų013.6 Ų13.60%06%0.057CC..  trans-144.9162.2-173.800000113A163 F369 V372A163-A392 WeakPolarHBondContact CA-O 3.36Å; A163-A392 WeakPolarHBondContact CB-O 3.36Å; F369-A392 HydrophobicContact CB-CB 4.44Å; F369-A392 WeakPolarHBondContact O-CA 3.37Å; V372-A392 HydrophobicContact CB-CB 4.05Å; V372-A392 HydrophobicContact CG2-CB 3.47Å; V372-A392 VanDerWaalsContact CG2-CB 3.47Å
393R94.3Very high95.7Very high130 Ų13013.5 Ų13.549%0.4916%0.057SC..SBendtrans-87.6-24.4177.856.5177.4174-166.5-3.1113.9P162 Q236 D370P162-R393 VanDerWaalsContact O-CA 3.31Å; P162-R393 WeakPolarHBondContact O-CA 3.46Å; P162-R393 WeakPolarHBondContact O-CB 3.44Å; Q236-R393 VanDerWaalsContact OE1-NH2 3.08Å; D370-R393 WeakPolarHBondContact O-CG 3.42Å; D370-R393 PolarHBondContact O-N 3.1Å; D370-R393 IonicContact OD1-CZ 2.86Å; D370-R393 VanDerWaalsContact OD1-CZ 3.31Å; D370-R393 IonicContact OD1-NE 2.78Å; D370-R393 IonicContact OD1-NH2 2.71Å; D370-R393 PolarHBondContact OD1-NH2 3.47Å
394K95.6Very high95.5Very high6 Ų613.7 Ų13.73%0.0266%0.057CC..EExtended strand (participates in β ladder)trans-125.4141.1-179.5-179.9171172.8175.70110.1A203 L204 Q206 R207 E208 D370 W371 V372A203-K394 VanDerWaalsContact O-CE 3.27Å; A203-K394 WeakPolarHBondContact O-CE 3.22Å; A203-K394 PolarHBondContact O-NZ 3.45Å; L204-K394 PolarHBondContact O-NZ 3.29Å; L204-K394 VanDerWaalsContact O-NZ 3.1Å; Q206-K394 WeakPolarHBondContact O-CE 3.25Å; Q206-K394 PolarHBondContact O-NZ 2.9Å; R207-K394 VanDerWaalsContact O-CB 3.3Å; R207-K394 WeakPolarHBondContact O-CB 3.3Å; R207-K394 WeakPolarHBondContact O-CD 3.44Å; R207-K394 VanDerWaalsContact O-CG 3.27Å; R207-K394 WeakPolarHBondContact O-CG 3.22Å; E208-K394 CarbonylContact O-C 3.6Å; E208-K394 WeakPolarHBondContact O-CA 3.41Å; D370-K394 PolarHBondContact O-N 3.15Å; W371-K394 WeakPolarHBondContact CA-O 3.47Å; W371-K394 HydrophobicContact CD2-CD 3.99Å; W371-K394 HydrophobicContact CG-CB 4.34Å; W371-K394 HydrophobicContact CG-CD 4.27Å; W371-K394 HydrophobicContact CG-CG 4.5Å; W371-K394 HydrophobicContact CZ2-CD 4.11Å; V372-K394 PolarHBondContact N-O 3.19Å
395C97.4Very high95.3Very high0 Ų014.3 Ų14.30%06%0.062CC..EExtended strand (participates in β ladder)trans-125.1149.2168.682.60000113.8L166 E208 L209 A210 V372 L389L166-C395 HydrophobicContact CD1-CB 4.41Å; L166-C395 HydrophobicContact CD2-CB 4.02Å; E208-C395 PolarHBondContact O-N 3.28Å; L209-C395 VanDerWaalsContact CD1-SG 3.58Å; A210-C395 PolarHBondContact N-O 3.28Å; A210-C395 VanDerWaalsContact N-O 3.09Å; V372-C395 CarbonylContact O-C 3.53Å; V372-C395 WeakPolarHBondContact O-CA 3.13Å; L389-C395 HydrophobicContact CD2-CB 3.34Å
396I98.3Very high94.9Very high1 Ų114.8 Ų14.81%0.0056%0.064CC..EExtended strand (participates in β ladder)trans-126.9115.5175.8-54.3-176.9000107.2A203 A210 I227 W371 V372 V373 I374A203-I396 HydrophobicContact CB-CD1 4.36Å; A210-I396 HydrophobicContact CB-CG1 4.46Å; A210-I396 CarbonylContact O-C 3.55Å; A210-I396 WeakPolarHBondContact O-CA 3.36Å; I227-I396 HydrophobicContact CG2-CD1 3.38Å; W371-I396 HydrophobicContact CE3-CD1 3.52Å; W371-I396 HydrophobicContact CZ3-CD1 3.61Å; V372-I396 PolarHBondContact O-N 3.31Å; V373-I396 CarbonylContact C-O 3.57Å; V373-I396 WeakPolarHBondContact CA-O 3.48Å; V373-I396 HydrophobicContact CG2-CB 4.3Å; I374-I396 PolarHBondContact N-O 3.03Å
397L98.4Very high94.5Very high0 Ų019.7 Ų19.70%09%0.094CC..EExtended strand (participates in β ladder)trans-103.6122.9-178.2-50.8-177.3000108.7L209 A210 V211 V212 I374 C377 L389 L422 L426L209-L397 HydrophobicContact CD1-CD1 4.09Å; L209-L397 HydrophobicContact CD1-CG 4.2Å; A210-L397 PolarHBondContact O-N 3.24Å; V211-L397 CarbonylContact C-O 3.56Å; V211-L397 VanDerWaalsContact CA-O 3.29Å; V211-L397 WeakPolarHBondContact CA-O 3.4Å; V211-L397 HydrophobicContact CG2-CB 4.37Å; V212-L397 PolarHBondContact N-O 3.34Å; I374-L397 HydrophobicContact CB-CD2 4.04Å; I374-L397 HydrophobicContact CD1-CD2 4.1Å; I374-L397 HydrophobicContact CG1-CD2 4.19Å; C377-L397 HydrophobicContact CB-CB 4.21Å; L389-L397 HydrophobicContact CD2-CD2 4.49Å; L397-L422 HydrophobicContact CD1-CD2 3.92Å; L397-L422 HydrophobicContact CD1-CG 3.99Å; L397-L422 HydrophobicContact CD2-CD2 4.36Å; L397-L426 HydrophobicContact CD1-CD1 3.47Å; L397-L426 VanDerWaalsContact CD1-CD1 3.47Å
398A98.1Very high94.1Very high0 Ų020.5 Ų20.50%010%0.099CC..EExtended strand (participates in β ladder)trans-119140.8174.900000110.1V212 K220 V224 I374 D375 E376 C377V212-A398 HydrophobicContact CB-CB 4.31Å; V212-A398 WeakPolarHBondContact O-CA 3.26Å; K220-A398 HydrophobicContact CD-CB 4.34Å; K220-A398 HydrophobicContact CG-CB 4.28Å; V224-A398 HydrophobicContact CG2-CB 3.38Å; I374-A398 PolarHBondContact O-N 3.31Å; D375-A398 CarbonylContact C-O 3.57Å; E376-A398 PolarHBondContact N-O 3.03Å; C377-A398 PolarHBondContact N-O 2.96Å
399G96.5Very high93.8Very high0 Ų025.4 Ų25.40%012%0.12CC..EExtended strand (participates in β ladder)trans168-162.2178.400000112.5V212 G214 M423V212-G399 PolarHBondContact O-N 3.15Å; G214-G399 PolarHBondContact N-O 3.01Å; G399-M423 VanDerWaalsContact C-CE 3.5Å; G399-M423 VanDerWaalsContact CA-SD 3.56Å; G399-M423 WeakPolarHBondContact O-CE 3.39Å
400D96.3Very high93.5Very high3 Ų325.9 Ų25.92%0.01612%0.123CC..  trans-147.9107.4174.4-1762.3000111H213 A378 K402 Q403 Y457H213-D400 IonicContact CD2-OD1 3.79Å; H213-D400 IonicContact CE1-OD1 3.16Å; H213-D400 IonicContact NE2-OD1 2.85Å; H213-D400 PolarHBondContact NE2-OD1 3.08Å; A378-D400 WeakPolarHBondContact CB-O 3.47Å; D400-K402 PolarHBondContact O-N 2.78Å; D400-K402 WeakPolarHBondContact OD1-CB 3.14Å; D400-K402 PolarHBondContact OD1-N 2.65Å; D400-Q403 HydrophobicContact CB-CB 4.35Å; D400-Q403 HydrophobicContact CB-CG 4.27Å; D400-Q403 PolarHBondContact O-N 2.97Å; D400-Q403 VanDerWaalsContact O-N 3.17Å; D400-Q403 WeakPolarHBondContact OD2-CG 3.5Å; D400-Q403 PolarHBondContact OD2-NE2 2.92Å; D400-Y457 PolarHBondContact OD2-OH 3.44Å
401Y94.7Very high93.2Very high32 Ų3232.6 Ų32.613%0.12515%0.154CC..THydrogen-bonded Turntrans-72.9-8.7179.977.5-74.4000113.6H213 E424 I427 R595H213-Y401 AromaticContact CE1-CD1 3.84Å; H213-Y401 AromaticContact CE1-CE1 3.41Å; H213-Y401 VanDerWaalsContact CE1-CE1 3.41Å; H213-Y401 WeakPolarHBondContact CE1-CE1 3.47Å; H213-Y401 AromaticContact ND1-CE1 3.71Å; H213-Y401 AromaticContact NE2-CD1 3.84Å; H213-Y401 AromaticContact NE2-CE1 3.9Å; Y401-E424 HydrophobicContact CD2-CG 3.99Å; Y401-E424 HydrophobicContact CG-CG 4.45Å; Y401-I427 HydrophobicContact CD1-CD1 3.42Å; Y401-I427 VanDerWaalsContact CD1-CD1 3.42Å; Y401-I427 HydrophobicContact CE1-CD1 3.82Å; Y401-I427 HydrophobicContact CE1-CG2 4.06Å; Y401-I427 HydrophobicContact CG-CD1 4.01Å; Y401-R595 PolarHBondContact O-NE 3.34Å; Y401-R595 PolarHBondContact O-NH1 3.13Å
402K95.3Very high93.2Very high38 Ų3835.1 Ų35.117%0.16517%0.173CC..THydrogen-bonded Turntrans-87.3-7.9171.4-59-71.7-172.8141.80112.5D400 M456 Y457 R595 N598D400-K402 PolarHBondContact O-N 2.78Å; D400-K402 WeakPolarHBondContact OD1-CB 3.14Å; D400-K402 PolarHBondContact OD1-N 2.65Å; K402-M456 HydrophobicContact CB-SD 4Å; K402-M456 WeakPolarHBondContact CD-O 3.29Å; K402-M456 HydrophobicContact CD-SD 4.07Å; K402-M456 WeakPolarHBondContact CE-O 3.48Å; K402-M456 PolarHBondContact NZ-O 3.32Å; K402-Y457 HydrophobicContact CB-CD1 4.44Å; K402-Y457 HydrophobicContact CB-CE1 3.62Å; K402-Y457 HydrophobicContact CG-CD1 4.18Å; K402-Y457 HydrophobicContact CG-CE1 3.81Å; K402-R595 WeakPolarHBondContact O-CG 3.31Å; K402-N598 PolarHBondContact O-ND2 3.33Å
403Q93.8Very high93.1Very high13 Ų1335.1 Ų35.16%0.06117%0.173CC..SBendtrans-94.7-174.8169.7-72-178.776.600111.1P216 D400 R595 V599P216-Q403 HydrophobicContact CG-CG 4.46Å; D400-Q403 HydrophobicContact CB-CB 4.35Å; D400-Q403 HydrophobicContact CB-CG 4.27Å; D400-Q403 PolarHBondContact O-N 2.97Å; D400-Q403 VanDerWaalsContact O-N 3.17Å; D400-Q403 WeakPolarHBondContact OD2-CG 3.5Å; D400-Q403 PolarHBondContact OD2-NE2 2.92Å; Q403-R595 WeakPolarHBondContact O-CD 3.47Å; Q403-V599 HydrophobicContact CB-CG2 3.53Å; Q403-V599 HydrophobicContact CG-CG2 3.54Å
404L91.1Very high92.9Very high4 Ų429.8 Ų29.82%0.02116%0.156CC..  trans-56.3130-172-74.5172.3000112.8V564 D565 R596 V599L404-V564 HydrophobicContact CD1-CG1 4.49Å; L404-D565 HydrophobicContact CD1-CB 4.07Å; L404-R596 HydrophobicContact CD2-CB 3.88Å; L404-R596 HydrophobicContact CD2-CG 4.21Å; L404-V599 HydrophobicContact CD1-CG1 4.45Å; L404-V599 HydrophobicContact CG-CB 4.49Å; L404-V599 HydrophobicContact CG-CG2 4.09Å
405P91.6Very high92.7Very high24 Ų2433.8 Ų33.816%0.15619%0.19CC..  trans-71.9178.317334.4-36.4000110.8T407P405-T407 PolarHBondContact O-N 3.34Å
406P90.3Very high92.5Very high9 Ų938.7 Ų38.76%0.05821%0.212CC..  trans-59130.3173.1-20.132.9000111.1A380 L381 I408 S419A380-P406 VanDerWaalsContact C-CG 3.44Å; A380-P406 WeakPolarHBondContact O-CG 3.25Å; L381-P406 HydrophobicContact CD2-CB 3.59Å; L381-P406 HydrophobicContact CD2-CG 4.17Å; L381-P406 HydrophobicContact CG-CB 3.91Å; P406-I408 PolarHBondContact O-N 3.47Å; P406-S419 WeakPolarHBondContact CD-O 3.41Å
407T86.3Confident92.2Very high103 Ų10340.1 Ų40.163%0.63223%0.227SC*.  trans-68.6124.7176.4-46.20000110.3P405P405-T407 PolarHBondContact O-N 3.34Å
408I88.1Confident92Very high26 Ų2640.7 Ų40.713%0.13323%0.23CC..  trans-129.1136.1-177.1-67.5161000108.5E18 L381 P406 S410 A414 L418 S419E18-I408 WeakPolarHBondContact OE1-CA 3.24Å; E18-I408 VanDerWaalsContact OE2-CG2 3.25Å; E18-I408 WeakPolarHBondContact OE2-CG2 3.07Å; L381-I408 HydrophobicContact CD2-CD1 3.99Å; L381-I408 HydrophobicContact CD2-CG1 4.06Å; P406-I408 PolarHBondContact O-N 3.47Å; I408-S410 WeakPolarHBondContact CG2-O 3.42Å; I408-A414 HydrophobicContact CB-CB 4.29Å; I408-A414 HydrophobicContact CD1-CB 4.26Å; I408-A414 HydrophobicContact CG2-CB 3.94Å; I408-L418 HydrophobicContact CD1-CB 3.91Å; I408-L418 HydrophobicContact CD1-CD2 4.24Å; I408-L418 HydrophobicContact CD1-CG 3.8Å; I408-L418 WeakPolarHBondContact CD1-O 3.48Å; I408-L418 HydrophobicContact CG1-CD2 4.35Å; I408-L418 HydrophobicContact CG1-CG 4.35Å; I408-L418 HydrophobicContact CG2-CD2 4.15Å; I408-S419 VanDerWaalsContact CD1-N 3.25Å
409K86.6Confident91.7Very high104 Ų10442.7 Ų42.745%0.45224%0.243SC..SBendtrans-80.9-44179.9-67.1-63.3-164.5151.80112E18 A21 E25 Q411E18-K409 VanDerWaalsContact CD-N 3.35Å; E18-K409 PolarHBondContact OE1-N 3.05Å; E18-K409 PolarHBondContact OE2-N 3.28Å; E18-K409 VanDerWaalsContact OE2-N 3.11Å; A21-K409 HydrophobicContact CB-CB 4.39Å; E25-K409 IonicContact OE1-NZ 3.26Å; E25-K409 PolarHBondContact OE1-NZ 2.88Å; E25-K409 VanDerWaalsContact OE2-CD 3.31Å; E25-K409 WeakPolarHBondContact OE2-CD 3.27Å; E25-K409 WeakPolarHBondContact OE2-CE 3.23Å; E25-K409 IonicContact OE2-NZ 3.6Å; E25-K409 PolarHBondContact OE2-NZ 2.78Å; K409-Q411 PolarHBondContact O-N 2.98Å
410S89.6Confident91.6Very high10 Ų1045.6 Ų45.67%0.0726%0.259CS..  trans-79.2100.4178.9-179.90000110.9E18 I408 T412 A413 A414E18-S410 VanDerWaalsContact OE2-CB 3.23Å; E18-S410 WeakPolarHBondContact OE2-CB 3.35Å; E18-S410 PolarHBondContact OE2-N 2.99Å; I408-S410 WeakPolarHBondContact CG2-O 3.42Å; S410-T412 PolarHBondContact O-N 3.16Å; S410-T412 PolarHBondContact OG-OG1 3.19Å; S410-A413 PolarHBondContact O-N 3.32Å; S410-A413 VanDerWaalsContact O-N 3.08Å; S410-A413 WeakPolarHBondContact OG-CB 3.48Å; S410-A413 PolarHBondContact OG-N 2.64Å; S410-A413 VanDerWaalsContact OG-N 3.15Å; S410-A414 PolarHBondContact O-N 3.11Å
411Q87.8Confident91.7Very high157 Ų15745.4 Ų45.473%0.73426%0.258SS*.Hα-helixtrans-53.9-34.7172.5-72.9-74.5-1.600112.2K409 A415K409-Q411 PolarHBondContact O-N 2.98Å; Q411-A415 WeakPolarHBondContact O-CB 3.47Å; Q411-A415 PolarHBondContact O-N 3.32Å
412T92.1Very high91.8Very high78 Ų7843.9 Ų43.948%0.47925%0.252SS..Hα-helixtrans-71.1-40176.449.30000112.2E17 S410 K416E17-T412 VanDerWaalsContact OE1-CB 3.23Å; E17-T412 WeakPolarHBondContact OE1-CB 3.45Å; E17-T412 PolarHBondContact OE1-OG1 2.84Å; S410-T412 PolarHBondContact O-N 3.16Å; S410-T412 PolarHBondContact OG-OG1 3.19Å; T412-K416 WeakPolarHBondContact O-CB 3.43Å; T412-K416 WeakPolarHBondContact O-CD 3.35Å; T412-K416 WeakPolarHBondContact O-CG 3.38Å; T412-K416 PolarHBondContact O-N 2.94Å
413A93.1Very high91.9Very high0 Ų042.1 Ų42.10%024%0.244CC..Hα-helixtrans-67.2-41174.600000111.8L14 E17 S410 K416 G417 L418L14-A413 HydrophobicContact CD2-CB 4.3Å; E17-A413 HydrophobicContact CB-CB 4.4Å; E17-A413 HydrophobicContact CG-CB 4.27Å; S410-A413 PolarHBondContact O-N 3.32Å; S410-A413 VanDerWaalsContact O-N 3.08Å; S410-A413 WeakPolarHBondContact OG-CB 3.48Å; S410-A413 PolarHBondContact OG-N 2.64Å; S410-A413 VanDerWaalsContact OG-N 3.15Å; A413-K416 PolarHBondContact O-N 3.11Å; A413-G417 PolarHBondContact O-N 3.36Å; A413-L418 HydrophobicContact CB-CB 4.34Å; A413-L418 HydrophobicContact CB-CD2 3.86Å; A413-L418 WeakPolarHBondContact O-CB 3.24Å; A413-L418 PolarHBondContact O-N 2.77Å
414A90.4Very high92Very high17 Ų1742.3 Ų42.314%0.1425%0.245CC..Iπ-helixtrans-57-52.9173.300000111.2I408 S410 K416 G417 S419I408-A414 HydrophobicContact CB-CB 4.29Å; I408-A414 HydrophobicContact CD1-CB 4.26Å; I408-A414 HydrophobicContact CG2-CB 3.94Å; S410-A414 PolarHBondContact O-N 3.11Å; A414-K416 VanDerWaalsContact C-N 3.29Å; A414-K416 PolarHBondContact O-N 2.88Å; A414-G417 WeakPolarHBondContact O-CA 3.38Å; A414-G417 PolarHBondContact O-N 2.99Å; A414-S419 PolarHBondContact O-OG 2.82Å
415A90.4Very high92.2Very high91 Ų9144.2 Ų44.275%0.75225%0.252SS*.Iπ-helixtrans-61.7-31.4179.300000113.8Q411 G417Q411-A415 WeakPolarHBondContact O-CB 3.47Å; Q411-A415 PolarHBondContact O-N 3.32Å; A415-G417 PolarHBondContact O-N 3.22Å
416K93.3Very high92.5Very high103 Ų10343 Ų4345%0.44824%0.244SC..Iπ-helixtrans-73.6-5.6172.8-69.4165.9-170.3171.20113.4K10 L14 E17 T412 A413 A414K10-K416 WeakPolarHBondContact CE-O 3.24Å; K10-K416 PolarHBondContact NZ-O 3.42Å; L14-K416 HydrophobicContact CD1-CB 4.29Å; L14-K416 HydrophobicContact CD2-CB 3.44Å; L14-K416 VanDerWaalsContact CD2-CB 3.44Å; L14-K416 HydrophobicContact CD2-CD 3.48Å; L14-K416 VanDerWaalsContact CD2-CD 3.48Å; L14-K416 HydrophobicContact CD2-CG 4.11Å; E17-K416 IonicContact OE1-NZ 3.16Å; E17-K416 PolarHBondContact OE1-NZ 3.45Å; E17-K416 IonicContact OE2-NZ 3.29Å; E17-K416 PolarHBondContact OE2-NZ 3.44Å; T412-K416 WeakPolarHBondContact O-CB 3.43Å; T412-K416 WeakPolarHBondContact O-CD 3.35Å; T412-K416 WeakPolarHBondContact O-CG 3.38Å; T412-K416 PolarHBondContact O-N 2.94Å; A413-K416 PolarHBondContact O-N 3.11Å; A414-K416 VanDerWaalsContact C-N 3.29Å; A414-K416 PolarHBondContact O-N 2.88Å
417G92.1Very high92.7Very high31 Ų3143.4 Ų43.432%0.3225%0.246SC..Iπ-helixtrans111.313.1172.700000115.7A413 A414 A415 S419 L420A413-G417 PolarHBondContact O-N 3.36Å; A414-G417 WeakPolarHBondContact O-CA 3.38Å; A414-G417 PolarHBondContact O-N 2.99Å; A415-G417 PolarHBondContact O-N 3.22Å; G417-S419 PolarHBondContact O-N 3.24Å; G417-L420 PolarHBondContact O-N 3.14Å
418L93.9Very high93.1Very high12 Ų1244.7 Ų44.76%0.06324%0.244CC..Iπ-helixtrans-66.9-24.4174.8-173.262.2000112.4L14 L15 E18 L381 I408 A413 L420L14-L418 HydrophobicContact CB-CB 4.29Å; L14-L418 HydrophobicContact CB-CD1 4.18Å; L14-L418 HydrophobicContact CB-CD2 4.37Å; L14-L418 HydrophobicContact CD1-CB 4.23Å; L15-L418 HydrophobicContact CD2-CD1 4.25Å; E18-L418 HydrophobicContact CB-CD2 3.8Å; E18-L418 HydrophobicContact CG-CD2 4.15Å; L381-L418 HydrophobicContact CD2-CD1 4.12Å; L381-L418 HydrophobicContact CD2-CG 3.98Å; L381-L418 WeakPolarHBondContact CD2-O 3.44Å; I408-L418 HydrophobicContact CD1-CB 3.91Å; I408-L418 HydrophobicContact CD1-CD2 4.24Å; I408-L418 HydrophobicContact CD1-CG 3.8Å; I408-L418 WeakPolarHBondContact CD1-O 3.48Å; I408-L418 HydrophobicContact CG1-CD2 4.35Å; I408-L418 HydrophobicContact CG1-CG 4.35Å; I408-L418 HydrophobicContact CG2-CD2 4.15Å; A413-L418 HydrophobicContact CB-CB 4.34Å; A413-L418 HydrophobicContact CB-CD2 3.86Å; A413-L418 WeakPolarHBondContact O-CB 3.24Å; A413-L418 PolarHBondContact O-N 2.77Å; L418-L420 VanDerWaalsContact C-N 3.31Å
419S92.8Very high93.3Very high41 Ų4147.3 Ų47.329%0.28726%0.261SS..THydrogen-bonded Turntrans-75.3-15.5177.152.80000114.1P406 I408 A414 G417 S421P406-S419 WeakPolarHBondContact CD-O 3.41Å; I408-S419 VanDerWaalsContact CD1-N 3.25Å; A414-S419 PolarHBondContact O-OG 2.82Å; G417-S419 PolarHBondContact O-N 3.24Å; S419-S421 PolarHBondContact O-N 3.08Å
420L95.1Very high93.7Very high61 Ų6143.4 Ų43.432%0.31924%0.244SC..  trans-72.9110.5178-175.166.2000109.2G417 L418 E424 R425G417-L420 PolarHBondContact O-N 3.14Å; L418-L420 VanDerWaalsContact C-N 3.31Å; L420-E424 HydrophobicContact CD1-CB 3.95Å; L420-E424 HydrophobicContact CD1-CG 3.65Å; L420-R425 HydrophobicContact CD2-CB 3.99Å; L420-R425 HydrophobicContact CD2-CG 4.17Å; L420-R425 HydrophobicContact CG-CB 4.12Å
421S97Very high93.8Very high0 Ų044.2 Ų44.20%025%0.254CS..BIsolated β-bridgetrans-71.5156.217670.80000111.5A378 S419 M423 E424 R425A378-S421 WeakPolarHBondContact O-CB 3.4Å; S419-S421 PolarHBondContact O-N 3.08Å; S421-M423 VanDerWaalsContact C-N 3.26Å; S421-M423 PolarHBondContact O-N 3.42Å; S421-E424 PolarHBondContact O-N 3.19Å; S421-E424 VanDerWaalsContact OG-CB 3.24Å; S421-E424 WeakPolarHBondContact OG-CB 3.16Å; S421-E424 PolarHBondContact OG-N 3.46Å; S421-E424 VanDerWaalsContact OG-N 3.13Å; S421-R425 PolarHBondContact O-N 3.16Å
422L97Very high93.9Very high0 Ų042.4 Ų42.40%025%0.249CC..Hα-helixtrans-55.1-45174.5177.563.5000111.4E382 C385 L389 L397 R425 L426E382-L422 HydrophobicContact CB-CB 4.11Å; E382-L422 HydrophobicContact CG-CB 3.93Å; E382-L422 HydrophobicContact CG-CD1 4.02Å; E382-L422 HydrophobicContact CG-CG 4.49Å; C385-L422 HydrophobicContact CB-CD2 3.87Å; L389-L422 HydrophobicContact CD1-CD2 3.44Å; L389-L422 VanDerWaalsContact CD1-CD2 3.44Å; L397-L422 HydrophobicContact CD1-CD2 3.92Å; L397-L422 HydrophobicContact CD1-CG 3.99Å; L397-L422 HydrophobicContact CD2-CD2 4.36Å; L422-R425 PolarHBondContact O-N 3.1Å; L422-L426 HydrophobicContact CD1-CD1 3.79Å; L422-L426 HydrophobicContact CD1-CG 4.19Å; L422-L426 HydrophobicContact CG-CD1 3.8Å; L422-L426 WeakPolarHBondContact O-CD1 3.47Å; L422-L426 VanDerWaalsContact O-CG 3.24Å; L422-L426 WeakPolarHBondContact O-CG 3.39Å; L422-L426 PolarHBondContact O-N 3.45Å
423M97.1Very high93.9Very high0 Ų041.6 Ų41.60%025%0.247CC..Hα-helixtrans-60.2-48.6179.4177.4172.2-17900111.3V211 H213 C377 A378 G399 S421 L426 I427V211-M423 HydrophobicContact CG1-CE 3.74Å; V211-M423 HydrophobicContact CG1-CG 4.05Å; V211-M423 HydrophobicContact CG1-SD 4.49Å; H213-M423 HydrophobicContact CB-CE 4.22Å; C377-M423 HydrophobicContact CB-CB 4.15Å; C377-M423 HydrophobicContact CB-SD 4.36Å; A378-M423 HydrophobicContact CB-SD 3.99Å; G399-M423 VanDerWaalsContact C-CE 3.5Å; G399-M423 VanDerWaalsContact CA-SD 3.56Å; G399-M423 WeakPolarHBondContact O-CE 3.39Å; S421-M423 VanDerWaalsContact C-N 3.26Å; S421-M423 PolarHBondContact O-N 3.42Å; M423-L426 PolarHBondContact O-N 3.3Å; M423-I427 HydrophobicContact CE-CD1 3.84Å; M423-I427 HydrophobicContact CG-CD1 3.68Å; M423-I427 HydrophobicContact CG-CG1 4.43Å; M423-I427 WeakPolarHBondContact O-CD1 3.25Å; M423-I427 WeakPolarHBondContact O-CG1 3.48Å; M423-I427 PolarHBondContact O-N 2.9Å
424E96.4Very high94Very high18 Ų1841.6 Ų41.68%0.08425%0.247CC..Hα-helixtrans-62.5-44.2179.5-173.4171.3168.300111.8Y401 L420 S421 L426 I427 H428 R595Y401-E424 HydrophobicContact CD2-CG 3.99Å; Y401-E424 HydrophobicContact CG-CG 4.45Å; L420-E424 HydrophobicContact CD1-CB 3.95Å; L420-E424 HydrophobicContact CD1-CG 3.65Å; S421-E424 PolarHBondContact O-N 3.19Å; S421-E424 VanDerWaalsContact OG-CB 3.24Å; S421-E424 WeakPolarHBondContact OG-CB 3.16Å; S421-E424 PolarHBondContact OG-N 3.46Å; S421-E424 VanDerWaalsContact OG-N 3.13Å; E424-L426 VanDerWaalsContact C-N 3.34Å; E424-L426 PolarHBondContact O-N 3.05Å; E424-I427 PolarHBondContact O-N 2.94Å; E424-H428 PolarHBondContact O-CD2 3.01Å; E424-H428 PolarHBondContact O-N 3.05Å; E424-R595 IonicContact OE1-CZ 3.44Å; E424-R595 IonicContact OE1-NH1 3.59Å; E424-R595 PolarHBondContact OE1-NH1 3.05Å; E424-R595 IonicContact OE1-NH2 2.7Å; E424-R595 PolarHBondContact OE1-NH2 3.42Å; E424-R595 IonicContact OE2-CZ 3.95Å; E424-R595 IonicContact OE2-NH1 2.68Å; E424-R595 PolarHBondContact OE2-NH1 2.88Å; E424-R595 IonicContact OE2-NH2 2.72Å
425R96.3Very high94.2Very high43 Ų4341.2 Ų41.216%0.16224%0.243CC..Hα-helixtrans-57.8-44.2175.6-173.9174.864.272.9-12.8112.3L170 E382 L420 S421 L422 H428 T429L170-R425 PolarHBondContact O-NH1 2.78Å; L170-R425 PolarHBondContact O-NH2 3.08Å; E382-R425 IonicContact OE1-CZ 3.65Å; E382-R425 IonicContact OE1-NE 3.77Å; E382-R425 PolarHBondContact OE1-NE 3.04Å; E382-R425 IonicContact OE1-NH2 3.83Å; E382-R425 PolarHBondContact OE1-NH2 2.75Å; E382-R425 IonicContact OE2-CZ 2.87Å; E382-R425 IonicContact OE2-NE 3.84Å; E382-R425 PolarHBondContact OE2-NE 3.27Å; E382-R425 IonicContact OE2-NH2 3.68Å; L420-R425 HydrophobicContact CD2-CB 3.99Å; L420-R425 HydrophobicContact CD2-CG 4.17Å; L420-R425 HydrophobicContact CG-CB 4.12Å; S421-R425 PolarHBondContact O-N 3.16Å; L422-R425 PolarHBondContact O-N 3.1Å; R425-H428 PolarHBondContact O-N 3.43Å; R425-T429 WeakPolarHBondContact O-CB 3.48Å; R425-T429 PolarHBondContact O-N 3.04Å; R425-T429 VanDerWaalsContact O-N 3.11Å; R425-T429 PolarHBondContact O-OG1 2.82Å
426L96.2Very high94.6Very high0 Ų039.6 Ų39.60%022%0.217CC..Hα-helixtrans-72.7-38.1-179-66.2165.9000112.3L170 L209 L397 L422 M423 E424 H428 T429 Y430L170-L426 HydrophobicContact CD2-CD1 3.52Å; L170-L426 HydrophobicContact CD2-CD2 3.84Å; L170-L426 HydrophobicContact CD2-CG 4.31Å; L209-L426 HydrophobicContact CD1-CD1 4.18Å; L209-L426 HydrophobicContact CD2-CD1 4.06Å; L209-L426 HydrophobicContact CD2-CD2 4.13Å; L209-L426 HydrophobicContact CD2-CG 4.49Å; L397-L426 HydrophobicContact CD1-CD1 3.47Å; L397-L426 VanDerWaalsContact CD1-CD1 3.47Å; L422-L426 HydrophobicContact CD1-CD1 3.79Å; L422-L426 HydrophobicContact CD1-CG 4.19Å; L422-L426 HydrophobicContact CG-CD1 3.8Å; L422-L426 WeakPolarHBondContact O-CD1 3.47Å; L422-L426 VanDerWaalsContact O-CG 3.24Å; L422-L426 WeakPolarHBondContact O-CG 3.39Å; L422-L426 PolarHBondContact O-N 3.45Å; M423-L426 PolarHBondContact O-N 3.3Å; E424-L426 VanDerWaalsContact C-N 3.34Å; E424-L426 PolarHBondContact O-N 3.05Å; L426-H428 VanDerWaalsContact C-N 3.3Å; L426-H428 PolarHBondContact O-N 2.94Å; L426-T429 PolarHBondContact O-N 2.75Å; L426-T429 VanDerWaalsContact O-N 3.09Å; L426-Y430 HydrophobicContact CD2-CD2 4.14Å; L426-Y430 HydrophobicContact CD2-CE2 4.05Å; L426-Y430 WeakPolarHBondContact O-CB 3.39Å; L426-Y430 PolarHBondContact O-N 3.1Å
427I95.3Very high94.8Very high17 Ų1735.9 Ų35.99%0.08720%0.202CC..Hα-helixtrans-57.8-45.3173-70166.5000110.2V211 Y401 M423 E424 T429 G431 V435V211-I427 HydrophobicContact CG1-CD1 4.29Å; V211-I427 HydrophobicContact CG1-CG1 4.15Å; Y401-I427 HydrophobicContact CD1-CD1 3.42Å; Y401-I427 VanDerWaalsContact CD1-CD1 3.42Å; Y401-I427 HydrophobicContact CE1-CD1 3.82Å; Y401-I427 HydrophobicContact CE1-CG2 4.06Å; Y401-I427 HydrophobicContact CG-CD1 4.01Å; M423-I427 HydrophobicContact CE-CD1 3.84Å; M423-I427 HydrophobicContact CG-CD1 3.68Å; M423-I427 HydrophobicContact CG-CG1 4.43Å; M423-I427 WeakPolarHBondContact O-CD1 3.25Å; M423-I427 WeakPolarHBondContact O-CG1 3.48Å; M423-I427 PolarHBondContact O-N 2.9Å; E424-I427 PolarHBondContact O-N 2.94Å; I427-T429 VanDerWaalsContact C-N 3.3Å; I427-T429 PolarHBondContact O-N 3.31Å; I427-G431 WeakPolarHBondContact O-CA 3.35Å; I427-G431 PolarHBondContact O-N 2.87Å; I427-V435 HydrophobicContact CB-CG2 4.35Å; I427-V435 HydrophobicContact CG1-CG2 3.68Å
428H93.9Very high95.1Very high130 Ų13034.4 Ų34.460%0.60219%0.187SC*.Hα-helixtrans-68.2-24.9176.1-73.5-57.8000114.5E424 R425 L426E424-H428 PolarHBondContact O-CD2 3.01Å; E424-H428 PolarHBondContact O-N 3.05Å; R425-H428 PolarHBondContact O-N 3.43Å; L426-H428 VanDerWaalsContact C-N 3.3Å; L426-H428 PolarHBondContact O-N 2.94Å
429T93.4Very high95.3Very high80 Ų8035.9 Ų35.949%0.49120%0.196SC..Hα-helixtrans-85-39.9-178.9-55.20000112.1R425 L426 I427R425-T429 WeakPolarHBondContact O-CB 3.48Å; R425-T429 PolarHBondContact O-N 3.04Å; R425-T429 VanDerWaalsContact O-N 3.11Å; R425-T429 PolarHBondContact O-OG1 2.82Å; L426-T429 PolarHBondContact O-N 2.75Å; L426-T429 VanDerWaalsContact O-N 3.09Å; I427-T429 VanDerWaalsContact C-N 3.3Å; I427-T429 PolarHBondContact O-N 3.31Å
430Y94.5Very high95.5Very high23 Ų2335.2 Ų35.29%0.0919%0.19CC..Hα-helixtrans-118.8-22.3-166.1-73.2-63.1000114.7V169 A174 P176 L209 L426 S433 V434V169-Y430 PolarHBondContact O-OH 2.78Å; A174-Y430 PolarHBondContact O-OH 2.86Å; A174-Y430 VanDerWaalsContact O-OH 3.11Å; P176-Y430 VanDerWaalsContact CD-CE1 3.47Å; P176-Y430 HydrophobicContact CG-CD1 4.11Å; P176-Y430 HydrophobicContact CG-CE1 4.13Å; L209-Y430 HydrophobicContact CD2-CD2 4.44Å; L426-Y430 HydrophobicContact CD2-CD2 4.14Å; L426-Y430 HydrophobicContact CD2-CE2 4.05Å; L426-Y430 WeakPolarHBondContact O-CB 3.39Å; L426-Y430 PolarHBondContact O-N 3.1Å; Y430-S433 WeakPolarHBondContact O-CB 3.5Å; Y430-S433 PolarHBondContact O-N 3.35Å; Y430-S433 PolarHBondContact O-OG 3.1Å; Y430-V434 VanDerWaalsContact CB-CG2 3.49Å; Y430-V434 HydrophobicContact CD2-CG2 4.45Å; Y430-V434 HydrophobicContact CG-CG1 4.13Å; Y430-V434 HydrophobicContact CG-CG2 4.26Å
431G92.3Very high95.6Very high27 Ų2732.3 Ų32.328%0.27818%0.175SC..G310 helixtrans50.9-140.4-177.100000113.3I427 S433 V434 V435I427-G431 WeakPolarHBondContact O-CA 3.35Å; I427-G431 PolarHBondContact O-N 2.87Å; G431-S433 PolarHBondContact O-N 2.96Å; G431-V434 PolarHBondContact O-N 3.2Å; G431-V435 WeakPolarHBondContact O-CB 3.42Å; G431-V435 WeakPolarHBondContact O-CG2 3.49Å; G431-V435 PolarHBondContact O-N 3.07Å; G431-V435 VanDerWaalsContact O-N 3.16Å
432D90.1Very high95.6Very high118 Ų11835.7 Ų35.763%0.63119%0.188SC*.G310 helixtrans-66.5-4.3-174.3-55.9-38.1000114.5V434 R436D432-V434 VanDerWaalsContact C-N 3.3Å; D432-R436 PolarHBondContact O-NH1 3.22Å
433S91.7Very high95.6Very high62 Ų6236.8 Ų36.843%0.43419%0.192SC..G310 helixtrans-70.4-24.9172.269.20000113.4F202 Y430 G431F202-S433 WeakPolarHBondContact CZ-O 3.31Å; Y430-S433 WeakPolarHBondContact O-CB 3.5Å; Y430-S433 PolarHBondContact O-N 3.35Å; Y430-S433 PolarHBondContact O-OG 3.1Å; G431-S433 PolarHBondContact O-N 2.96Å
434V94Very high95.6Very high0 Ų036.8 Ų36.80%019%0.192CC..THydrogen-bonded Turntrans-125.8-9.7176.2-55.20000113.5P176 F202 L209 V211 Y430 G431 D432P176-V434 HydrophobicContact CB-CG1 3.73Å; P176-V434 HydrophobicContact CG-CG1 3.54Å; F202-V434 WeakPolarHBondContact CE1-O 3.39Å; L209-V434 HydrophobicContact CD2-CB 4.23Å; L209-V434 HydrophobicContact CD2-CG1 4.1Å; L209-V434 HydrophobicContact CD2-CG2 4.21Å; L209-V434 HydrophobicContact CG-CB 4.27Å; L209-V434 HydrophobicContact CG-CG1 4.37Å; V211-V434 WeakPolarHBondContact CB-O 3.21Å; V211-V434 HydrophobicContact CG2-CG2 4.01Å; V211-V434 PolarHBondContact N-O 2.91Å; Y430-V434 VanDerWaalsContact CB-CG2 3.49Å; Y430-V434 HydrophobicContact CD2-CG2 4.45Å; Y430-V434 HydrophobicContact CG-CG1 4.13Å; Y430-V434 HydrophobicContact CG-CG2 4.26Å; G431-V434 PolarHBondContact O-N 3.2Å; D432-V434 VanDerWaalsContact C-N 3.3Å
435V96.5Very high95.7Very high8 Ų836.3 Ų36.35%0.04819%0.19CC..EExtended strand (participates in β ladder)trans-104.2136.4-173.2-176.40000111.3V211 H213 I427 G431V211-V435 HydrophobicContact CB-CG2 4Å; V211-V435 HydrophobicContact CG1-CG2 4.15Å; V211-V435 CarbonylContact O-C 3.57Å; V211-V435 WeakPolarHBondContact O-CA 3.34Å; H213-V435 HydrophobicContact CB-CG1 4Å; I427-V435 HydrophobicContact CB-CG2 4.35Å; I427-V435 HydrophobicContact CG1-CG2 3.68Å; G431-V435 WeakPolarHBondContact O-CB 3.42Å; G431-V435 WeakPolarHBondContact O-CG2 3.49Å; G431-V435 PolarHBondContact O-N 3.07Å; G431-V435 VanDerWaalsContact O-N 3.16Å
436R97.2Very high95.8Very high58 Ų5836.1 Ų36.122%0.21920%0.196CC..EExtended strand (participates in β ladder)trans-124.1127.5159.6-71.9-63.6179.1-85.69.7110.2E198 A199 F202 V211 H213 D432E198-R436 WeakPolarHBondContact OE1-CD 3.36Å; E198-R436 IonicContact OE1-CZ 3.77Å; E198-R436 IonicContact OE1-NE 2.78Å; E198-R436 PolarHBondContact OE1-NE 3.32Å; E198-R436 IonicContact OE1-NH2 3.18Å; A199-R436 HydrophobicContact CB-CB 3.96Å; F202-R436 HydrophobicContact CB-CG 3.89Å; F202-R436 HydrophobicContact CD1-CG 3.7Å; F202-R436 HydrophobicContact CD2-CG 4.15Å; F202-R436 HydrophobicContact CE1-CG 4.27Å; F202-R436 HydrophobicContact CG-CG 3.64Å; V211-R436 PolarHBondContact O-N 3.39Å; H213-R436 PolarHBondContact N-O 2.67Å; D432-R436 PolarHBondContact O-NH1 3.22Å
437M97.5Very high95.9Very high25 Ų2536.7 Ų36.712%0.12320%0.2CC..EExtended strand (participates in β ladder)trans-100.1127.8179.9-179.1-179.1155.400109.9H213 P215 Y457 R460 L461H213-M437 HydrophobicContact CB-CB 4.18Å; H213-M437 HydrophobicContact CB-CG 4.36Å; H213-M437 CarbonylContact O-C 3.42Å; H213-M437 VanDerWaalsContact O-CA 3.31Å; H213-M437 WeakPolarHBondContact O-CA 3.36Å; P215-M437 HydrophobicContact CG-CE 3.62Å; P215-M437 HydrophobicContact CG-CG 4.09Å; P215-M437 HydrophobicContact CG-SD 4.48Å; M437-Y457 HydrophobicContact CE-CD1 4.13Å; M437-Y457 HydrophobicContact CE-CG 4.32Å; M437-R460 HydrophobicContact CE-CB 4.07Å; M437-R460 VanDerWaalsContact SD-CZ 3.59Å; M437-R460 PolarHBondContact SD-NH2 2.98Å; M437-L461 HydrophobicContact CE-CD2 3.63Å
438L98.3Very high96Very high0 Ų036 Ų360%020%0.196CC..  trans-76.3134.7172.7-53.1-180000109.6S195 Q196 A199 V212 H213 P215 T218 K220 T223S195-L438 WeakPolarHBondContact O-CD2 3.24Å; Q196-L438 HydrophobicContact CB-CD2 4.43Å; Q196-L438 HydrophobicContact CG-CD1 4.42Å; Q196-L438 HydrophobicContact CG-CD2 3.95Å; A199-L438 HydrophobicContact CB-CD2 3.71Å; V212-L438 HydrophobicContact CG1-CD1 4.13Å; V212-L438 HydrophobicContact CG1-CD2 4.4Å; V212-L438 HydrophobicContact CG1-CG 4.17Å; H213-L438 PolarHBondContact O-N 2.93Å; P215-L438 WeakPolarHBondContact CD-O 3.37Å; T218-L438 HydrophobicContact CG2-CB 4.27Å; T218-L438 WeakPolarHBondContact O-CD1 3.44Å; K220-L438 HydrophobicContact CB-CD1 4.34Å; T223-L438 HydrophobicContact CG2-CD2 4.25Å; T223-L438 WeakPolarHBondContact OG1-CD1 3.14Å
439T97.9Very high96.2Very high43 Ų4330.6 Ų30.626%0.26417%0.172SC..  trans-113-34.8-169.553.70000113.8S195 R460 L461 T462S195-T439 WeakPolarHBondContact CB-OG1 3.41Å; S195-T439 PolarHBondContact OG-N 3.13Å; S195-T439 VanDerWaalsContact OG-N 3.13Å; T439-R460 WeakPolarHBondContact CB-O 3.3Å; T439-L461 WeakPolarHBondContact O-CA 3.46Å; T439-T462 PolarHBondContact O-N 3.06Å
440V98.1Very high96.4Very high26 Ų2631.7 Ų31.716%0.15817%0.171CC..EExtended strand (participates in β ladder)trans-82.1126.7179.3-173.30000110.2D193 T218 Y442 T462 H464D193-V440 HydrophobicContact CB-CB 4.28Å; D193-V440 HydrophobicContact CB-CG2 4.04Å; T218-V440 VanDerWaalsContact CA-O 3.24Å; T218-V440 WeakPolarHBondContact CA-O 3.5Å; V440-Y442 HydrophobicContact CB-CE2 4.15Å; V440-Y442 HydrophobicContact CG1-CE1 4.46Å; V440-Y442 HydrophobicContact CG1-CE2 3.81Å; V440-T462 WeakPolarHBondContact CA-O 3.48Å; V440-H464 HydrophobicContact CG1-CB 3.92Å
441Q97.4Very high96.5Very high0 Ų030.8 Ų30.80%017%0.168CC..EExtended strand (participates in β ladder)trans-114.3142.8177.972.577.222.600113.4T218 M444 M449 T462 H464T218-Q441 HydrophobicContact CG2-CB 4.05Å; Q441-M444 HydrophobicContact CG-CE 4.04Å; Q441-M444 PolarHBondContact NE2-O 3.33Å; Q441-M449 HydrophobicContact CG-CG 3.84Å; Q441-M449 HydrophobicContact CG-SD 3.48Å; Q441-M449 WeakPolarHBondContact CG-SD 3.38Å; Q441-M449 PolarHBondContact NE2-SD 3.25Å; Q441-M449 VanDerWaalsContact NE2-SD 3.36Å; Q441-T462 PolarHBondContact N-O 2.92Å; Q441-H464 WeakPolarHBondContact O-CB 3.26Å; Q441-H464 PolarHBondContact O-N 3.45Å
442Y97.1Very high96.8Very high71 Ų7129.5 Ų29.528%0.27815%0.154SC..SBendtrans-118.722-169.5-60.7-96.2000113.2D193 G217 V440 H464 V467D193-Y442 WeakPolarHBondContact CB-OH 3.39Å; D193-Y442 PolarHBondContact OD2-OH 3.31Å; D193-Y442 VanDerWaalsContact OD2-OH 3.11Å; G217-Y442 PolarHBondContact O-N 2.75Å; V440-Y442 HydrophobicContact CB-CE2 4.15Å; V440-Y442 HydrophobicContact CG1-CE1 4.46Å; V440-Y442 HydrophobicContact CG1-CE2 3.81Å; Y442-H464 HydrophobicContact CD1-CB 3.59Å; Y442-H464 AromaticContact CD1-CG 3.56Å; Y442-H464 AromaticContact CD1-ND1 3.79Å; Y442-H464 HydrophobicContact CE1-CB 3.7Å; Y442-H464 AromaticContact CE1-CD2 3.45Å; Y442-H464 VanDerWaalsContact CE1-CD2 3.45Å; Y442-H464 WeakPolarHBondContact CE1-CD2 3.35Å; Y442-H464 AromaticContact CE1-CG 3.34Å; Y442-H464 AromaticContact CE1-ND1 3.77Å; Y442-H464 AromaticContact CE1-NE2 3.94Å; Y442-H464 HydrophobicContact CG-CB 4.19Å; Y442-V467 WeakPolarHBondContact O-CG1 3.3Å
443R96.6Very high97.1Very high23 Ų2324.1 Ų24.19%0.08713%0.126CC..SBendtrans-116.2-57.5-173.6178.3-175.1-75178.6-4.5112.9H470 E571 T602 R605R443-H470 PolarHBondContact O-CE1 3.36Å; R443-H470 PolarHBondContact O-NE2 3.35Å; R443-E571 IonicContact CZ-OE2 3.65Å; R443-E571 IonicContact NE-OE2 3.89Å; R443-E571 PolarHBondContact NE-OE2 3.48Å; R443-E571 IonicContact NH2-OE2 2.74Å; R443-E571 PolarHBondContact NH2-OE2 3.2Å; R443-T602 WeakPolarHBondContact CD-O 3.2Å; R443-T602 PolarHBondContact NH1-O 3.17Å; R443-R605 HydrophobicContact CG-CG 3.7Å; R443-R605 VanDerWaalsContact O-CA 3.26Å; R443-R605 WeakPolarHBondContact O-CA 3.33Å; R443-R605 VanDerWaalsContact O-CB 3.29Å; R443-R605 WeakPolarHBondContact O-CB 3.47Å; R443-R605 WeakPolarHBondContact O-CG 3.3Å
444M97.8Very high97.4Very high0 Ų027.7 Ų27.70%013%0.134CC..SBendtrans-97.6145.1-160.9-65.5168.4-65.500111.2P216 Q441 I448 M449 V467 T602 A604 R605P216-M444 HydrophobicContact CB-CE 4.27Å; Q441-M444 HydrophobicContact CG-CE 4.04Å; Q441-M444 PolarHBondContact NE2-O 3.33Å; M444-I448 HydrophobicContact CB-CB 4.3Å; M444-I448 HydrophobicContact CB-CG2 4.37Å; M444-I448 HydrophobicContact CG-CG2 4.25Å; M444-I448 HydrophobicContact SD-CG2 4.32Å; M444-M449 HydrophobicContact CB-CB 4.17Å; M444-M449 HydrophobicContact CE-CB 4.23Å; M444-M449 HydrophobicContact CE-CG 4.19Å; M444-V467 WeakPolarHBondContact O-CG2 3.37Å; M444-T602 HydrophobicContact SD-CG2 3.79Å; M444-A604 WeakPolarHBondContact CG-O 3.26Å; M444-R605 CarbonylContact C-O 3.59Å; M444-R605 WeakPolarHBondContact CA-O 3.46Å
445N98.3Very high97.5Very high9 Ų931.1 Ų31.15%0.04815%0.15CC..  trans-55146.4159.3-177.1-74000109.7A447 I448 M449 V467 H470 P487 R605N445-A447 VanDerWaalsContact C-N 3.28Å; N445-A447 PolarHBondContact O-N 3.46Å; N445-A447 WeakPolarHBondContact OD1-CB 3.24Å; N445-A447 PolarHBondContact OD1-N 3.28Å; N445-I448 HydrophobicContact CB-CD1 4.07Å; N445-I448 HydrophobicContact CB-CG1 4.22Å; N445-I448 PolarHBondContact O-N 3.04Å; N445-I448 VanDerWaalsContact O-N 3.08Å; N445-M449 PolarHBondContact O-N 3.11Å; N445-V467 WeakPolarHBondContact CA-O 3.41Å; N445-H470 PolarHBondContact N-NE2 3.2Å; N445-H470 PolarHBondContact ND2-O 2.89Å; N445-P487 HydrophobicContact CB-CB 4.12Å; N445-R605 PolarHBondContact N-O 3.19Å
446S97.8Very high97.5Very high39 Ų3931.3 Ų31.327%0.27315%0.151SC..Hα-helixtrans-55.6-41.2-176.857.70000112.7I448 M449 E450 E468S446-I448 VanDerWaalsContact C-N 3.29Å; S446-I448 PolarHBondContact O-N 3.18Å; S446-M449 WeakPolarHBondContact O-CB 3.36Å; S446-M449 PolarHBondContact O-N 3.25Å; S446-M449 VanDerWaalsContact O-N 3.16Å; S446-E450 WeakPolarHBondContact O-CB 3.34Å; S446-E450 PolarHBondContact O-N 3.12Å; S446-E468 WeakPolarHBondContact CB-O 3.42Å; S446-E468 PolarHBondContact N-O 2.59Å; S446-E468 PolarHBondContact OG-O 3.17Å; S446-E468 VanDerWaalsContact OG-O 3.11Å
447A97.6Very high97.4Very high11 Ų1128.7 Ų28.79%0.09114%0.141CC..Hα-helixtrans-63.8-31179.300000113.5N445 P487 L488 H629 V633N445-A447 VanDerWaalsContact C-N 3.28Å; N445-A447 PolarHBondContact O-N 3.46Å; N445-A447 WeakPolarHBondContact OD1-CB 3.24Å; N445-A447 PolarHBondContact OD1-N 3.28Å; A447-P487 HydrophobicContact CB-CG 3.95Å; A447-L488 HydrophobicContact CB-CD1 4.01Å; A447-L488 HydrophobicContact CB-CG 4.35Å; A447-H629 PolarHBondContact O-NE2 3.44Å; A447-V633 HydrophobicContact CB-CG1 3.85Å
448I97.9Very high97.3Very high2 Ų233.9 Ų33.91%0.0117%0.165CC..Hα-helixtrans-77.5-40.9175.2-56.6175.2000110.1M444 N445 S446 P487 L488 V601 A604 I608M444-I448 HydrophobicContact CB-CB 4.3Å; M444-I448 HydrophobicContact CB-CG2 4.37Å; M444-I448 HydrophobicContact CG-CG2 4.25Å; M444-I448 HydrophobicContact SD-CG2 4.32Å; N445-I448 HydrophobicContact CB-CD1 4.07Å; N445-I448 HydrophobicContact CB-CG1 4.22Å; N445-I448 PolarHBondContact O-N 3.04Å; N445-I448 VanDerWaalsContact O-N 3.08Å; S446-I448 VanDerWaalsContact C-N 3.29Å; S446-I448 PolarHBondContact O-N 3.18Å; I448-P487 HydrophobicContact CD1-CB 4.39Å; I448-P487 HydrophobicContact CG1-CB 4.32Å; I448-L488 HydrophobicContact CG1-CD2 3.86Å; I448-V601 HydrophobicContact CG2-CG1 4.14Å; I448-A604 HydrophobicContact CD1-CB 4.12Å; I448-A604 HydrophobicContact CG2-CB 4.5Å; I448-I608 HydrophobicContact CD1-CG2 4.21Å; I448-I608 HydrophobicContact CG1-CG2 4.13Å; I448-I608 HydrophobicContact CG2-CG2 4.41Å
449M97.8Very high97.3Very high17 Ų1736.3 Ų36.38%0.08419%0.189CC..Hα-helixtrans-66-41.6179-179.9-159.174.800112.2Q441 M444 N445 S446 W451 A452 S453 L461 A463Q441-M449 HydrophobicContact CG-CG 3.84Å; Q441-M449 HydrophobicContact CG-SD 3.48Å; Q441-M449 WeakPolarHBondContact CG-SD 3.38Å; Q441-M449 PolarHBondContact NE2-SD 3.25Å; Q441-M449 VanDerWaalsContact NE2-SD 3.36Å; M444-M449 HydrophobicContact CB-CB 4.17Å; M444-M449 HydrophobicContact CE-CB 4.23Å; M444-M449 HydrophobicContact CE-CG 4.19Å; N445-M449 PolarHBondContact O-N 3.11Å; S446-M449 WeakPolarHBondContact O-CB 3.36Å; S446-M449 PolarHBondContact O-N 3.25Å; S446-M449 VanDerWaalsContact O-N 3.16Å; M449-W451 PolarHBondContact O-N 3.12Å; M449-A452 PolarHBondContact O-N 3.21Å; M449-A452 VanDerWaalsContact O-N 3.15Å; M449-S453 WeakPolarHBondContact O-CB 3.2Å; M449-S453 PolarHBondContact O-N 2.76Å; M449-L461 VanDerWaalsContact CE-O 3.25Å; M449-L461 WeakPolarHBondContact CE-O 3.48Å; M449-L461 HydrophobicContact CG-CB 4.07Å; M449-L461 HydrophobicContact CG-CD1 4.46Å; M449-L461 HydrophobicContact SD-CB 3.97Å; M449-A463 HydrophobicContact CE-CB 4.2Å; M449-A463 HydrophobicContact SD-CB 3.82Å; M449-A463 PolarHBondContact SD-N 3.42Å
450E97.8Very high97.2Very high103 Ų10339.5 Ų39.548%0.48120%0.196SC..Hα-helixtrans-57-48.8-169.7-177.8172.7-161.600112.8S446 A452 S453 K454 H629S446-E450 WeakPolarHBondContact O-CB 3.34Å; S446-E450 PolarHBondContact O-N 3.12Å; E450-A452 PolarHBondContact O-N 2.95Å; E450-S453 WeakPolarHBondContact O-CB 3.33Å; E450-S453 PolarHBondContact O-N 3.47Å; E450-K454 WeakPolarHBondContact O-CB 3.34Å; E450-K454 PolarHBondContact O-N 2.78Å; E450-H629 IonicContact OE2-CE1 2.74Å
451W97.7Very high97.2Very high4 Ų438.5 Ų38.52%0.01519%0.19CC..Hα-helixtrans-56.1-50.7174.8169.979.6000111.9M449 S453 K454 E455 I597 V601 F622 L626 H629M449-W451 PolarHBondContact O-N 3.12Å; W451-S453 VanDerWaalsContact C-N 3.33Å; W451-S453 PolarHBondContact O-N 3.34Å; W451-K454 PolarHBondContact O-N 2.86Å; W451-E455 WeakPolarHBondContact O-CB 3.38Å; W451-E455 WeakPolarHBondContact O-CG 3.24Å; W451-E455 PolarHBondContact O-N 3Å; W451-I597 HydrophobicContact CH2-CG2 4.03Å; W451-I597 HydrophobicContact CZ2-CG2 4.46Å; W451-V601 HydrophobicContact CE3-CB 4.22Å; W451-V601 HydrophobicContact CE3-CG1 3.79Å; W451-V601 HydrophobicContact CE3-CG2 4.35Å; W451-V601 HydrophobicContact CH2-CB 4.45Å; W451-V601 HydrophobicContact CH2-CG2 4.09Å; W451-V601 HydrophobicContact CZ3-CB 3.65Å; W451-V601 HydrophobicContact CZ3-CG1 3.77Å; W451-V601 HydrophobicContact CZ3-CG2 3.72Å; W451-F622 AromaticContact CH2-CE1 3.53Å; W451-F622 HydrophobicContact CH2-CE1 3.53Å; W451-F622 AromaticContact CH2-CZ 3.52Å; W451-F622 HydrophobicContact CH2-CZ 3.52Å; W451-F622 HydrophobicContact CZ2-CD1 4.18Å; W451-F622 AromaticContact CZ2-CE1 3.39Å; W451-F622 HydrophobicContact CZ2-CE1 3.39Å; W451-F622 HydrophobicContact CZ2-CE2 4.21Å; W451-F622 AromaticContact CZ2-CZ 3.4Å; W451-F622 HydrophobicContact CZ2-CZ 3.4Å; W451-F622 VanDerWaalsContact CZ2-CZ 3.4Å; W451-L626 HydrophobicContact CD2-CD1 3.74Å; W451-L626 HydrophobicContact CE3-CD1 4.13Å; W451-L626 HydrophobicContact CG-CD1 4.15Å; W451-L626 HydrophobicContact CH2-CD1 4.44Å; W451-L626 HydrophobicContact CZ2-CB 3.83Å; W451-L626 HydrophobicContact CZ2-CD1 4.06Å; W451-L626 HydrophobicContact CZ2-CD2 4.41Å; W451-L626 HydrophobicContact CZ2-CG 4.31Å; W451-L626 HydrophobicContact CZ3-CD1 4.48Å; W451-L626 VanDerWaalsContact NE1-CA 3.28Å; W451-H629 HydrophobicContact CB-CB 4.44Å; W451-H629 HydrophobicContact CG-CB 4.49Å
452A97Very high97.2Very high0 Ų042.1 Ų42.10%021%0.212CC..Hα-helixtrans-63.8-41.8179.700000111M449 E450 M456 Y457 T602M449-A452 PolarHBondContact O-N 3.21Å; M449-A452 VanDerWaalsContact O-N 3.15Å; E450-A452 PolarHBondContact O-N 2.95Å; A452-M456 WeakPolarHBondContact O-CB 3.43Å; A452-M456 PolarHBondContact O-N 3.47Å; A452-Y457 HydrophobicContact CB-CE2 4.5Å; A452-Y457 VanDerWaalsContact O-CD2 3.22Å; A452-Y457 WeakPolarHBondContact O-CD2 3.42Å; A452-T602 HydrophobicContact CB-CG2 3.75Å
453S97.8Very high97.2Very high6 Ų639.9 Ų39.94%0.04221%0.209CC..Hα-helixtrans-55.9-53.8176.9-168.60000110.9M449 E450 W451 Y457 H458 G459 R460 L461M449-S453 WeakPolarHBondContact O-CB 3.2Å; M449-S453 PolarHBondContact O-N 2.76Å; E450-S453 WeakPolarHBondContact O-CB 3.33Å; E450-S453 PolarHBondContact O-N 3.47Å; W451-S453 VanDerWaalsContact C-N 3.33Å; W451-S453 PolarHBondContact O-N 3.34Å; S453-Y457 CarbonylContact O-C 3.44Å; S453-Y457 WeakPolarHBondContact O-CA 3.33Å; S453-Y457 PolarHBondContact O-N 3.4Å; S453-H458 PolarHBondContact O-N 3.19Å; S453-G459 PolarHBondContact O-N 3.35Å; S453-G459 WeakPolarHBondContact OG-CA 3.37Å; S453-G459 PolarHBondContact OG-O 3.18Å; S453-R460 PolarHBondContact OG-N 2.98Å; S453-L461 WeakPolarHBondContact OG-CB 3.39Å; S453-L461 PolarHBondContact OG-N 2.98Å; S453-L461 PolarHBondContact OG-O 3.32Å
454K97.3Very high97.3Very high136 Ų13641.8 Ų41.859%0.59122%0.218SC*.Hα-helixtrans-60.5-55.6-179.5-175.6179.2178.4-179.60112E450 W451E450-K454 WeakPolarHBondContact O-CB 3.34Å; E450-K454 PolarHBondContact O-N 2.78Å; W451-K454 PolarHBondContact O-N 2.86Å
455E96.4Very high97.2Very high72 Ų7246.2 Ų46.234%0.33625%0.25SC..Hα-helixtrans-79.8-30.8-168.8-58.1-70.7114.100113.6W451 F622 S625W451-E455 WeakPolarHBondContact O-CB 3.38Å; W451-E455 WeakPolarHBondContact O-CG 3.24Å; W451-E455 PolarHBondContact O-N 3Å; E455-F622 HydrophobicContact CB-CD2 4.34Å; E455-F622 HydrophobicContact CB-CE2 3.67Å; E455-F622 HydrophobicContact CB-CZ 4.43Å; E455-S625 VanDerWaalsContact CD-OG 3.3Å; E455-S625 WeakPolarHBondContact OE2-CB 3.34Å; E455-S625 PolarHBondContact OE2-OG 2.87Å
456M96Very high97.1Very high13 Ų1349.6 Ų49.66%0.06427%0.274CS..Hα-helixtrans-110.5-30.6-174.7-78.9-84.1169.900114.6K402 A452 D594 N598 F622K402-M456 HydrophobicContact CB-SD 4Å; K402-M456 WeakPolarHBondContact CD-O 3.29Å; K402-M456 HydrophobicContact CD-SD 4.07Å; K402-M456 WeakPolarHBondContact CE-O 3.48Å; K402-M456 PolarHBondContact NZ-O 3.32Å; A452-M456 WeakPolarHBondContact O-CB 3.43Å; A452-M456 PolarHBondContact O-N 3.47Å; M456-D594 VanDerWaalsContact CE-C 3.49Å; M456-D594 HydrophobicContact CE-CB 3.32Å; M456-N598 HydrophobicContact CE-CB 4.03Å; M456-N598 HydrophobicContact CG-CB 3.93Å; M456-N598 HydrophobicContact SD-CB 4.22Å; M456-F622 HydrophobicContact CE-CD2 4.41Å; M456-F622 HydrophobicContact CE-CE1 4.26Å; M456-F622 HydrophobicContact CE-CE2 3.53Å; M456-F622 HydrophobicContact CE-CZ 3.46Å; M456-F622 VanDerWaalsContact CE-CZ 3.46Å; M456-F622 HydrophobicContact CG-CE2 4.11Å; M456-F622 HydrophobicContact CG-CZ 4.05Å
457Y96.6Very high97.1Very high2 Ų248 Ų481%0.00826%0.262CS..Hα-helixtrans-122.915.3-168-53.1-78.4000114.2P215 P216 D400 K402 M437 A452 S453 G459 R460 L461 N598P215-Y457 HydrophobicContact CB-CD1 4.03Å; P215-Y457 HydrophobicContact CB-CE1 3.79Å; P215-Y457 HydrophobicContact CG-CD1 3.92Å; P215-Y457 HydrophobicContact CG-CE1 4.01Å; P216-Y457 WeakPolarHBondContact CD-OH 3.14Å; D400-Y457 PolarHBondContact OD2-OH 3.44Å; K402-Y457 HydrophobicContact CB-CD1 4.44Å; K402-Y457 HydrophobicContact CB-CE1 3.62Å; K402-Y457 HydrophobicContact CG-CD1 4.18Å; K402-Y457 HydrophobicContact CG-CE1 3.81Å; M437-Y457 HydrophobicContact CE-CD1 4.13Å; M437-Y457 HydrophobicContact CE-CG 4.32Å; A452-Y457 HydrophobicContact CB-CE2 4.5Å; A452-Y457 VanDerWaalsContact O-CD2 3.22Å; A452-Y457 WeakPolarHBondContact O-CD2 3.42Å; S453-Y457 CarbonylContact O-C 3.44Å; S453-Y457 WeakPolarHBondContact O-CA 3.33Å; S453-Y457 PolarHBondContact O-N 3.4Å; Y457-G459 VanDerWaalsContact C-N 3.32Å; Y457-G459 PolarHBondContact O-N 2.82Å; Y457-R460 WeakPolarHBondContact O-CB 3.23Å; Y457-R460 PolarHBondContact O-N 3.14Å; Y457-L461 HydrophobicContact CD2-CD1 3.55Å; Y457-L461 HydrophobicContact CD2-CG 4.16Å; Y457-L461 HydrophobicContact CE2-CD1 4.07Å; Y457-L461 HydrophobicContact CG-CD1 4.03Å; Y457-L461 HydrophobicContact CG-CD2 4.37Å; Y457-L461 HydrophobicContact CG-CG 4.18Å; Y457-N598 PolarHBondContact OH-ND2 2.9Å
458H95.3Very high97Very high135 Ų13550.6 Ų50.663%0.62527%0.273SS*.THydrogen-bonded Turntrans60.434.8176.3-50.4-80.9000114.1S453 R460S453-H458 PolarHBondContact O-N 3.19Å; H458-R460 PolarHBondContact O-N 3.12Å
459G96.6Very high97Very high50 Ų5057.4 Ų57.452%0.51530%0.302SS..THydrogen-bonded Turntrans73.44.9179.700000115.1S453 Y457 L461S453-G459 PolarHBondContact O-N 3.35Å; S453-G459 WeakPolarHBondContact OG-CA 3.37Å; S453-G459 PolarHBondContact OG-O 3.18Å; Y457-G459 VanDerWaalsContact C-N 3.32Å; Y457-G459 PolarHBondContact O-N 2.82Å; G459-L461 PolarHBondContact O-N 3.4Å
460R96.7Very high97Very high110 Ų11057.1 Ų57.142%0.41530%0.301SS..  trans-81.4-4.6-170.6-61.5-170.3-68.9-177.2-1.1115.8M437 T439 S453 Y457 H458M437-R460 HydrophobicContact CE-CB 4.07Å; M437-R460 VanDerWaalsContact SD-CZ 3.59Å; M437-R460 PolarHBondContact SD-NH2 2.98Å; T439-R460 WeakPolarHBondContact CB-O 3.3Å; S453-R460 PolarHBondContact OG-N 2.98Å; Y457-R460 WeakPolarHBondContact O-CB 3.23Å; Y457-R460 PolarHBondContact O-N 3.14Å; H458-R460 PolarHBondContact O-N 3.12Å
461L97.9Very high97Very high6 Ų653.3 Ų53.33%0.03128%0.284CS..  trans-85.5135.4177.3-52-176.8000111.7P215 T218 M437 T439 M449 S453 Y457 G459P215-L461 HydrophobicContact CB-CD1 4.24Å; P215-L461 HydrophobicContact CB-CD2 3.64Å; P215-L461 HydrophobicContact CG-CD2 3.71Å; T218-L461 HydrophobicContact CG2-CD2 4.39Å; M437-L461 HydrophobicContact CE-CD2 3.63Å; T439-L461 WeakPolarHBondContact O-CA 3.46Å; M449-L461 VanDerWaalsContact CE-O 3.25Å; M449-L461 WeakPolarHBondContact CE-O 3.48Å; M449-L461 HydrophobicContact CG-CB 4.07Å; M449-L461 HydrophobicContact CG-CD1 4.46Å; M449-L461 HydrophobicContact SD-CB 3.97Å; S453-L461 WeakPolarHBondContact OG-CB 3.39Å; S453-L461 PolarHBondContact OG-N 2.98Å; S453-L461 PolarHBondContact OG-O 3.32Å; Y457-L461 HydrophobicContact CD2-CD1 3.55Å; Y457-L461 HydrophobicContact CD2-CG 4.16Å; Y457-L461 HydrophobicContact CE2-CD1 4.07Å; Y457-L461 HydrophobicContact CG-CD1 4.03Å; Y457-L461 HydrophobicContact CG-CD2 4.37Å; Y457-L461 HydrophobicContact CG-CG 4.18Å; G459-L461 PolarHBondContact O-N 3.4Å
462T97.9Very high97Very high75 Ų7553.1 Ų53.146%0.4628%0.283SS..EExtended strand (participates in β ladder)trans-119.9141.6174.257.90000110.6T439 V440 Q441T439-T462 PolarHBondContact O-N 3.06Å; V440-T462 WeakPolarHBondContact CA-O 3.48Å; Q441-T462 PolarHBondContact N-O 2.92Å
463A97.6Very high96.9Very high25 Ų2556.9 Ų56.921%0.20730%0.299CS..EExtended strand (participates in β ladder)trans-85.7129.2179.500000110.1M449 E468M449-A463 HydrophobicContact CE-CB 4.2Å; M449-A463 HydrophobicContact SD-CB 3.82Å; M449-A463 PolarHBondContact SD-N 3.42Å; A463-E468 HydrophobicContact CB-CB 4.14Å; A463-E468 HydrophobicContact CB-CG 4.23Å
464H98Very high96.8Very high62 Ų6260.8 Ų60.829%0.28732%0.32SS..  trans-64.4144.8170.6-173-102.4000110.4V440 Q441 Y442 S466 V467 E468V440-H464 HydrophobicContact CG1-CB 3.92Å; Q441-H464 WeakPolarHBondContact O-CB 3.26Å; Q441-H464 PolarHBondContact O-N 3.45Å; Y442-H464 HydrophobicContact CD1-CB 3.59Å; Y442-H464 AromaticContact CD1-CG 3.56Å; Y442-H464 AromaticContact CD1-ND1 3.79Å; Y442-H464 HydrophobicContact CE1-CB 3.7Å; Y442-H464 AromaticContact CE1-CD2 3.45Å; Y442-H464 VanDerWaalsContact CE1-CD2 3.45Å; Y442-H464 WeakPolarHBondContact CE1-CD2 3.35Å; Y442-H464 AromaticContact CE1-CG 3.34Å; Y442-H464 AromaticContact CE1-ND1 3.77Å; Y442-H464 AromaticContact CE1-NE2 3.94Å; Y442-H464 HydrophobicContact CG-CB 4.19Å; H464-S466 WeakPolarHBondContact ND1-CB 3.41Å; H464-S466 PolarHBondContact ND1-N 3.08Å; H464-S466 PolarHBondContact ND1-OG 3.32Å; H464-S466 PolarHBondContact O-N 3.39Å; H464-V467 HydrophobicContact CB-CG2 4.4Å; H464-V467 WeakPolarHBondContact O-CG2 3.47Å; H464-V467 PolarHBondContact O-N 3.12Å; H464-E468 PolarHBondContact O-N 3.25Å
465S96.6Very high96.8Very high94 Ų9455.6 Ų55.666%0.65730%0.298SS*.THydrogen-bonded Turntrans-55.5-28.1-175.757.90000114V467S465-V467 VanDerWaalsContact C-N 3.27Å; S465-V467 PolarHBondContact O-N 3.03Å
466S95.9Very high96.6Very high80 Ų8057.3 Ų57.356%0.55932%0.315SS*.THydrogen-bonded Turntrans-70.7-15.6176.466.90000115.2H464H464-S466 WeakPolarHBondContact ND1-CB 3.41Å; H464-S466 PolarHBondContact ND1-N 3.08Å; H464-S466 PolarHBondContact ND1-OG 3.32Å; H464-S466 PolarHBondContact O-N 3.39Å
467V96.9Very high96.5Very high4 Ų460.1 Ų60.12%0.02435%0.347CS..THydrogen-bonded Turntrans-125.2-19.2179.3-64.10000114Y442 M444 N445 H464 S465 K469 H470Y442-V467 WeakPolarHBondContact O-CG1 3.3Å; M444-V467 WeakPolarHBondContact O-CG2 3.37Å; N445-V467 WeakPolarHBondContact CA-O 3.41Å; H464-V467 HydrophobicContact CB-CG2 4.4Å; H464-V467 WeakPolarHBondContact O-CG2 3.47Å; H464-V467 PolarHBondContact O-N 3.12Å; S465-V467 VanDerWaalsContact C-N 3.27Å; S465-V467 PolarHBondContact O-N 3.03Å; V467-K469 PolarHBondContact O-N 2.89Å; V467-H470 PolarHBondContact O-CD2 2.97Å; V467-H470 PolarHBondContact O-N 3.3Å; V467-H470 PolarHBondContact O-NE2 2.96Å
468E96.5Very high96.5Very high67 Ų6761 Ų6131%0.31335%0.353SS..THydrogen-bonded Turntrans-42.3-49.5-176.5-168.8-151.2161.400113.1S446 A463 H464S446-E468 WeakPolarHBondContact CB-O 3.42Å; S446-E468 PolarHBondContact N-O 2.59Å; S446-E468 PolarHBondContact OG-O 3.17Å; S446-E468 VanDerWaalsContact OG-O 3.11Å; A463-E468 HydrophobicContact CB-CB 4.14Å; A463-E468 HydrophobicContact CB-CG 4.23Å; H464-E468 PolarHBondContact O-N 3.25Å
469K96.9Very high96.4Very high144 Ų14457 Ų5763%0.62634%0.343SS*.THydrogen-bonded Turntrans-1149.6-172.1-64.2178.9175.297.80114.6V467V467-K469 PolarHBondContact O-N 2.89Å
470H97.6Very high96.3Very high12 Ų1259.1 Ų59.16%0.05635%0.349CS..  trans-73139.7-172.876.4163.6000113R443 N445 V467 R605 R606R443-H470 PolarHBondContact O-CE1 3.36Å; R443-H470 PolarHBondContact O-NE2 3.35Å; N445-H470 PolarHBondContact N-NE2 3.2Å; N445-H470 PolarHBondContact ND2-O 2.89Å; V467-H470 PolarHBondContact O-CD2 2.97Å; V467-H470 PolarHBondContact O-N 3.3Å; V467-H470 PolarHBondContact O-NE2 2.96Å; H470-R605 PolarHBondContact NE2-O 2.86Å; H470-R606 HydrophobicContact CB-CG 4.44Å
471L97.7Very high96.2Very high23 Ų2356.3 Ų56.312%0.1234%0.344CS..  trans-133166.4-175.2-67.7170000110.8K473 D474 S485 P487 R606L471-K473 VanDerWaalsContact C-N 3.32Å; L471-K473 HydrophobicContact CB-CG 4.12Å; L471-K473 PolarHBondContact O-N 3.15Å; L471-D474 PolarHBondContact N-OD2 2.74Å; L471-D474 PolarHBondContact O-N 3.38Å; L471-S485 WeakPolarHBondContact CD1-O 3.43Å; L471-P487 HydrophobicContact CD2-CB 3.91Å; L471-P487 HydrophobicContact CD2-CG 4.17Å; L471-R606 WeakPolarHBondContact O-CD 3.35Å; L471-R606 PolarHBondContact O-NH1 3.04Å
472L97.4Very high95.8Very high0 Ų061.9 Ų61.90%037%0.37CS..G310 helixtrans-65.3-35.4-178.9-72.9176.7000112.5D474 L475 V478 T484 L525 V530 E573 A574 R606 H607L472-D474 PolarHBondContact O-N 2.94Å; L472-D474 VanDerWaalsContact O-N 3.14Å; L472-L475 HydrophobicContact CD2-CD1 3.86Å; L472-L475 VanDerWaalsContact O-CB 3.3Å; L472-L475 WeakPolarHBondContact O-CB 3.26Å; L472-L475 PolarHBondContact O-N 2.82Å; L472-V478 WeakPolarHBondContact O-CB 3.32Å; L472-V478 WeakPolarHBondContact O-CG1 3.21Å; L472-T484 HydrophobicContact CB-CG2 4.24Å; L472-T484 PolarHBondContact N-O 2.58Å; L472-L525 HydrophobicContact CD1-CD2 3.85Å; L472-V530 HydrophobicContact CD1-CG2 4.37Å; L472-E573 HydrophobicContact CD2-CB 4.09Å; L472-A574 HydrophobicContact CD1-CB 4.12Å; L472-A574 HydrophobicContact CD2-CB 4.07Å; L472-R606 HydrophobicContact CD2-CB 3.95Å; L472-R606 HydrophobicContact CG-CB 4.17Å; L472-H607 HydrophobicContact CD1-CB 3.41Å; L472-H607 VanDerWaalsContact CD1-CB 3.41Å; L472-H607 HydrophobicContact CD2-CB 4.32Å; L472-H607 HydrophobicContact CG-CB 3.63Å
473K96Very high95.5Very high79 Ų7959.5 Ų59.534%0.34335%0.354SS..G310 helixtrans-59.9-19.6176.369.3-177.5179.7-170.10114.3L471 L475 C480 T484L471-K473 VanDerWaalsContact C-N 3.32Å; L471-K473 HydrophobicContact CB-CG 4.12Å; L471-K473 PolarHBondContact O-N 3.15Å; K473-L475 VanDerWaalsContact C-N 3.26Å; K473-C480 HydrophobicContact CB-CB 4.4Å; K473-T484 PolarHBondContact N-O 3.43Å; K473-T484 VanDerWaalsContact N-O 3.1Å
474D95.9Very high95.3Very high88 Ų8858.3 Ų58.347%0.47134%0.344SS..G310 helixtrans-83.4-4.2177.9-38.4-39.1000112.2L471 L472 R606L471-D474 PolarHBondContact N-OD2 2.74Å; L471-D474 PolarHBondContact O-N 3.38Å; L472-D474 PolarHBondContact O-N 2.94Å; L472-D474 VanDerWaalsContact O-N 3.14Å; D474-R606 IonicContact OD2-NH1 2.77Å
475L95.6Very high95.2Very high27 Ų2757.3 Ų57.314%0.14134%0.344CS..SBendtrans-77.2142.2175.1-69.7171.2000111.1L472 K473 G477 V478 E573L472-L475 HydrophobicContact CD2-CD1 3.86Å; L472-L475 VanDerWaalsContact O-CB 3.3Å; L472-L475 WeakPolarHBondContact O-CB 3.26Å; L472-L475 PolarHBondContact O-N 2.82Å; K473-L475 VanDerWaalsContact C-N 3.26Å; L475-G477 PolarHBondContact O-N 3.05Å; L475-G477 VanDerWaalsContact O-N 3.12Å; L475-V478 HydrophobicContact CB-CB 4.34Å; L475-V478 HydrophobicContact CB-CG2 3.66Å; L475-V478 PolarHBondContact O-N 3.39Å; L475-V478 VanDerWaalsContact O-N 3.12Å; L475-E573 HydrophobicContact CD1-CB 3.96Å; L475-E573 HydrophobicContact CD1-CG 4.02Å; L475-E573 HydrophobicContact CD2-CG 4.34Å
476P94.1Very high95.1Very high107 Ų10753.6 Ų53.670%0.69532%0.317SS*.THydrogen-bonded Turntrans-65.7116.1-175.926.3-34.7000111.7
477G92.3Very high95.2Very high72 Ų7250.8 Ų50.874%0.74230%0.297SS*.THydrogen-bonded Turntrans93.27.518000000115.1L475L475-G477 PolarHBondContact O-N 3.05Å; L475-G477 VanDerWaalsContact O-N 3.12Å
478V96.3Very high95.2Very high20 Ų2050.8 Ų50.812%0.12130%0.297CS..  trans-91.5131.9174.1-178.50000110.4L472 L475 T484 A528 V530L472-V478 WeakPolarHBondContact O-CB 3.32Å; L472-V478 WeakPolarHBondContact O-CG1 3.21Å; L475-V478 HydrophobicContact CB-CB 4.34Å; L475-V478 HydrophobicContact CB-CG2 3.66Å; L475-V478 PolarHBondContact O-N 3.39Å; L475-V478 VanDerWaalsContact O-N 3.12Å; V478-T484 HydrophobicContact CG1-CG2 3.62Å; V478-A528 CarbonylContact C-O 3.59Å; V478-A528 WeakPolarHBondContact CA-O 3.49Å; V478-V530 HydrophobicContact CG1-CG2 3.84Å; V478-V530 HydrophobicContact CG2-CG2 3.95Å
479A95.1Very high95.3Very high51 Ų5147.6 Ų47.642%0.42128%0.282SS..  trans-78.4144.1176.400000111.1V481 T484 A528A479-V481 PolarHBondContact O-N 3.17Å; A479-T484 PolarHBondContact O-OG1 3.36Å; A479-A528 PolarHBondContact N-O 3.45Å
480C94.3Very high95.3Very high95 Ų9540.9 Ų40.964%0.64225%0.253SS*.  trans-78.184.7176.4-173.70000111.1K473K473-C480 HydrophobicContact CB-CB 4.4Å
481V93.5Very high95.3Very high52 Ų5240.3 Ų40.332%0.31525%0.25SS..  trans-106.8170.5169.7-590000110.9A479 E483 T484 S485 A528A479-V481 PolarHBondContact O-N 3.17Å; V481-E483 HydrophobicContact CG2-CB 4.44Å; V481-E483 WeakPolarHBondContact CG2-OE2 3.47Å; V481-E483 PolarHBondContact O-N 2.9Å; V481-T484 HydrophobicContact CG2-CG2 3.61Å; V481-T484 WeakPolarHBondContact CG2-OG1 3.43Å; V481-T484 PolarHBondContact N-OG1 2.98Å; V481-T484 PolarHBondContact O-N 2.92Å; V481-T484 PolarHBondContact O-OG1 3.08Å; V481-S485 WeakPolarHBondContact O-CB 3.29Å; V481-S485 PolarHBondContact O-N 3.39Å; V481-S485 VanDerWaalsContact O-N 3.1Å; V481-S485 PolarHBondContact O-OG 3.42Å; V481-A528 HydrophobicContact CG2-CB 3.7Å
482E90.8Very high95.3Very high122 Ų12240.6 Ų40.657%0.5725%0.252SS*.Hα-helixtrans-53.9-52.4-179.1-63.6174.2169.400111.3T484 S485 T486 R637E482-T484 PolarHBondContact O-N 3.31Å; E482-T484 VanDerWaalsContact O-N 3.11Å; E482-S485 PolarHBondContact O-N 3.41Å; E482-T486 PolarHBondContact O-N 3.34Å; E482-R637 VanDerWaalsContact CB-NH2 3.31Å; E482-R637 IonicContact OE2-CZ 3.8Å; E482-R637 IonicContact OE2-NH2 2.76Å; E482-R637 PolarHBondContact OE2-NH2 3.07Å
483E90.3Very high95.2Very high26 Ų2640.7 Ų40.712%0.12125%0.252CS..Hα-helixtrans-58.8-30.8-178.8-62.479.8-17700113.3V481 L525 H607 R637V481-E483 HydrophobicContact CG2-CB 4.44Å; V481-E483 WeakPolarHBondContact CG2-OE2 3.47Å; V481-E483 PolarHBondContact O-N 2.9Å; E483-L525 HydrophobicContact CB-CD2 4.01Å; E483-H607 PolarHBondContact O-CE1 2.93Å; E483-H607 VanDerWaalsContact O-CE1 3.25Å; E483-H607 PolarHBondContact O-ND1 3.06Å; E483-R637 IonicContact OE1-CZ 3.52Å; E483-R637 IonicContact OE1-NH1 3.48Å; E483-R637 PolarHBondContact OE1-NH1 3.27Å; E483-R637 IonicContact OE1-NH2 3.13Å
484T94.6Very high95Very high0 Ų037.8 Ų37.80%024%0.244CC..Hα-helixtrans-89.4-10.9-179.6620000113.9L472 K473 V478 A479 V481 E482 A528 V530L472-T484 HydrophobicContact CB-CG2 4.24Å; L472-T484 PolarHBondContact N-O 2.58Å; K473-T484 PolarHBondContact N-O 3.43Å; K473-T484 VanDerWaalsContact N-O 3.1Å; V478-T484 HydrophobicContact CG1-CG2 3.62Å; A479-T484 PolarHBondContact O-OG1 3.36Å; V481-T484 HydrophobicContact CG2-CG2 3.61Å; V481-T484 WeakPolarHBondContact CG2-OG1 3.43Å; V481-T484 PolarHBondContact N-OG1 2.98Å; V481-T484 PolarHBondContact O-N 2.92Å; V481-T484 PolarHBondContact O-OG1 3.08Å; E482-T484 PolarHBondContact O-N 3.31Å; E482-T484 VanDerWaalsContact O-N 3.11Å; T484-A528 HydrophobicContact CG2-CB 3.93Å; T484-V530 HydrophobicContact CG2-CG2 4.37Å
485S95.2Very high94.5Very high40 Ų4036.7 Ų36.728%0.2825%0.253SS..Hα-helixtrans-98.4-14-176.6-61.40000113.2L471 V481 E482L471-S485 WeakPolarHBondContact CD1-O 3.43Å; V481-S485 WeakPolarHBondContact O-CB 3.29Å; V481-S485 PolarHBondContact O-N 3.39Å; V481-S485 VanDerWaalsContact O-N 3.1Å; V481-S485 PolarHBondContact O-OG 3.42Å; E482-S485 PolarHBondContact O-N 3.41Å
486T94.8Very high94.1Very high17 Ų1735.8 Ų35.810%0.10425%0.249CC..  trans-104.4139.5174.5-177.90000112.3E482 L488 L489 H607 E635E482-T486 PolarHBondContact O-N 3.34Å; T486-L488 PolarHBondContact OG1-N 3.42Å; T486-L488 PolarHBondContact OG1-O 3.41Å; T486-L489 HydrophobicContact CG2-CB 4.36Å; T486-H607 PolarHBondContact O-ND1 3.05Å; T486-E635 HydrophobicContact CG2-CB 4.36Å
487P96.8Very high93.6Very high21 Ų2133.7 Ų33.714%0.13625%0.247CC..SBendtrans-83-20.2171.433.6-32.9000113.4N445 A447 I448 L471 R606 H607 I608N445-P487 HydrophobicContact CB-CB 4.12Å; A447-P487 HydrophobicContact CB-CG 3.95Å; I448-P487 HydrophobicContact CD1-CB 4.39Å; I448-P487 HydrophobicContact CG1-CB 4.32Å; L471-P487 HydrophobicContact CD2-CB 3.91Å; L471-P487 HydrophobicContact CD2-CG 4.17Å; P487-R606 WeakPolarHBondContact CA-O 3.42Å; P487-H607 WeakPolarHBondContact O-CA 3.18Å; P487-I608 PolarHBondContact O-N 3.49Å
488L98Very high93.4Very high4 Ų431.5 Ų31.52%0.02122%0.218CC..EExtended strand (participates in β ladder)trans-130.5122.3-175-65.8177.7000109.7A447 I448 T486 I608 M630 V633 E635A447-L488 HydrophobicContact CB-CD1 4.01Å; A447-L488 HydrophobicContact CB-CG 4.35Å; I448-L488 HydrophobicContact CG1-CD2 3.86Å; T486-L488 PolarHBondContact OG1-N 3.42Å; T486-L488 PolarHBondContact OG1-O 3.41Å; L488-I608 HydrophobicContact CD2-CG2 3.54Å; L488-M630 HydrophobicContact CB-CE 4.28Å; L488-M630 HydrophobicContact CD2-CE 4.44Å; L488-V633 HydrophobicContact CD1-CB 4.13Å; L488-V633 HydrophobicContact CD1-CG1 4.14Å; L488-E635 PolarHBondContact O-N 3.32Å
489L98Very high93Very high0 Ų033.9 Ų33.90%024%0.235CC..EExtended strand (participates in β ladder)trans-131.1117.6175.517865.8000110.9T486 I491 H521 I608 A609 V610 M630 E635 R637T486-L489 HydrophobicContact CG2-CB 4.36Å; L489-I491 HydrophobicContact CD2-CD1 4.08Å; L489-I491 HydrophobicContact CD2-CG1 4.17Å; L489-I491 HydrophobicContact CG-CD1 4.47Å; L489-I491 HydrophobicContact CG-CG1 4.03Å; L489-H521 WeakPolarHBondContact CD2-CE1 3.39Å; L489-I608 PolarHBondContact N-O 2.74Å; L489-A609 HydrophobicContact CB-CB 4.24Å; L489-A609 HydrophobicContact CD2-CB 4.25Å; L489-A609 CarbonylContact O-C 3.54Å; L489-A609 WeakPolarHBondContact O-CA 3.28Å; L489-V610 PolarHBondContact O-N 3.41Å; L489-M630 VanDerWaalsContact C-CE 3.4Å; L489-M630 VanDerWaalsContact O-CE 3.23Å; L489-M630 WeakPolarHBondContact O-CE 3.42Å; L489-E635 CarbonylContact C-O 3.58Å; L489-E635 WeakPolarHBondContact CA-O 3.48Å; L489-E635 HydrophobicContact CD1-CB 3.98Å; L489-E635 HydrophobicContact CD1-CG 4.12Å; L489-R637 HydrophobicContact CD1-CG 4.02Å
490L98.1Very high92.6Very high2 Ų232.6 Ų32.61%0.0122%0.221CC..EExtended strand (participates in β ladder)trans-98.4123.9171.3179.964000109.1V610 T614 V627 M630 E635 V636 R637L490-V610 HydrophobicContact CD1-CB 4.29Å; L490-V610 HydrophobicContact CD1-CG1 4.36Å; L490-T614 HydrophobicContact CD2-CG2 4.21Å; L490-V627 HydrophobicContact CD2-CG1 4.04Å; L490-M630 HydrophobicContact CB-CB 4.23Å; L490-M630 HydrophobicContact CB-CE 4.27Å; L490-E635 PolarHBondContact N-O 3.25Å; L490-V636 HydrophobicContact CB-CG1 4.38Å; L490-V636 HydrophobicContact CB-CG2 4.24Å; L490-V636 HydrophobicContact CD2-CG1 4.13Å; L490-V636 HydrophobicContact CD2-CG2 4.26Å; L490-V636 HydrophobicContact CG-CG1 4.35Å; L490-V636 WeakPolarHBondContact O-CA 3.27Å; L490-R637 PolarHBondContact O-N 3.23Å
491I97.3Very high92.2Very high0 Ų031.6 Ų31.60%021%0.207CC..EExtended strand (participates in β ladder)trans-111.7100.2173.4-50.9171.4000108.4L489 I517 H521 V610 V611 C612 R637 Y642L489-I491 HydrophobicContact CD2-CD1 4.08Å; L489-I491 HydrophobicContact CD2-CG1 4.17Å; L489-I491 HydrophobicContact CG-CD1 4.47Å; L489-I491 HydrophobicContact CG-CG1 4.03Å; I491-I517 HydrophobicContact CB-CG2 4.36Å; I491-I517 HydrophobicContact CD1-CG2 4.02Å; I491-I517 HydrophobicContact CG2-CG2 3.68Å; I491-H521 HydrophobicContact CD1-CB 4.36Å; I491-V610 PolarHBondContact N-O 3.29Å; I491-V611 HydrophobicContact CB-CG1 4.46Å; I491-V611 HydrophobicContact CB-CG2 4.3Å; I491-V611 HydrophobicContact CD1-CG2 4.17Å; I491-V611 WeakPolarHBondContact O-CA 3.26Å; I491-C612 PolarHBondContact O-N 2.83Å; I491-R637 CarbonylContact C-O 3.54Å; I491-R637 WeakPolarHBondContact CA-O 3.09Å; I491-Y642 HydrophobicContact CD1-CE1 4.22Å; I491-Y642 HydrophobicContact CD1-CE2 3.97Å; I491-Y642 WeakPolarHBondContact CD1-OH 3.29Å; I491-Y642 HydrophobicContact CG1-CE2 4.12Å; I491-Y642 HydrophobicContact CG2-CD2 3.89Å; I491-Y642 HydrophobicContact CG2-CE2 3.71Å
492D96.9Very high91.1Very high30 Ų3038.2 Ų38.216%0.1624%0.235CC..EExtended strand (participates in β ladder)trans-82.8125.2-174.7-169.57.4000112.1A494 C612 T614 R637 A639D492-A494 WeakPolarHBondContact OD1-CB 3.5Å; D492-A494 PolarHBondContact OD1-N 3.02Å; D492-C612 WeakPolarHBondContact CA-O 3.49Å; D492-T614 HydrophobicContact CB-CG2 4Å; D492-T614 VanDerWaalsContact CG-OG1 3.23Å; D492-T614 VanDerWaalsContact OD1-CG2 3.32Å; D492-T614 WeakPolarHBondContact OD1-CG2 3.38Å; D492-T614 PolarHBondContact OD1-N 2.93Å; D492-T614 PolarHBondContact OD1-OG1 3.41Å; D492-T614 WeakPolarHBondContact OD2-CG2 3.42Å; D492-T614 PolarHBondContact OD2-OG1 2.88Å; D492-R637 PolarHBondContact N-O 2.77Å; D492-A639 WeakPolarHBondContact O-CB 3.37Å; D492-A639 PolarHBondContact O-N 3.03Å
493T94.8Very high90Very high1 Ų136.1 Ų36.11%0.00623%0.227CC..  trans-98.20.1176.169.20000113.5C496 L498 E514 I517 V611 C612 D613 A639T493-C496 VanDerWaalsContact O-CB 3.27Å; T493-C496 WeakPolarHBondContact O-CB 3.35Å; T493-C496 PolarHBondContact O-N 3.09Å; T493-L498 HydrophobicContact CG2-CD1 4.07Å; T493-E514 HydrophobicContact CG2-CG 4.23Å; T493-I517 HydrophobicContact CG2-CD1 3.57Å; T493-V611 HydrophobicContact CG2-CG1 3.93Å; T493-C612 PolarHBondContact N-O 2.99Å; T493-C612 PolarHBondContact OG1-O 3.24Å; T493-D613 VanDerWaalsContact OG1-CA 3.25Å; T493-D613 WeakPolarHBondContact OG1-CA 3.16Å; T493-D613 WeakPolarHBondContact OG1-CB 3.46Å; T493-D613 PolarHBondContact OG1-N 2.98Å; T493-D613 VanDerWaalsContact OG1-N 3.08Å; T493-A639 HydrophobicContact CG2-CB 4.21Å
494A92.5Very high88.2Confident19 Ų1940 Ų4016%0.15726%0.264CS..THydrogen-bonded Turntrans-55.2141.4175.700000111.6D492 C496 D613 Q615D492-A494 WeakPolarHBondContact OD1-CB 3.5Å; D492-A494 PolarHBondContact OD1-N 3.02Å; A494-C496 PolarHBondContact O-N 3.43Å; A494-C496 PolarHBondContact O-SG 3.44Å; A494-D613 WeakPolarHBondContact CA-OD1 3.38Å; A494-D613 WeakPolarHBondContact CB-OD1 3.38Å; A494-Q615 HydrophobicContact CB-CB 4.15Å
495G85.5Confident86.2Confident65 Ų6544.7 Ų44.767%0.6729%0.289SS*.THydrogen-bonded Turntrans67.4-7.7-178.500000116.2G497G495-G497 PolarHBondContact O-N 3.11Å
496C86.9Confident84.4Confident8 Ų851.4 Ų51.45%0.05432%0.315CS..THydrogen-bonded Turntrans-86.4-3.2-174.4-59.70000114T493 A494 L498 A639 F640 I646T493-C496 VanDerWaalsContact O-CB 3.27Å; T493-C496 WeakPolarHBondContact O-CB 3.35Å; T493-C496 PolarHBondContact O-N 3.09Å; A494-C496 PolarHBondContact O-N 3.43Å; A494-C496 PolarHBondContact O-SG 3.44Å; C496-L498 VanDerWaalsContact C-N 3.27Å; C496-L498 HydrophobicContact CB-CD1 4.08Å; C496-L498 HydrophobicContact CB-CG 3.94Å; C496-L498 PolarHBondContact O-N 2.79Å; C496-A639 HydrophobicContact CB-CB 4.23Å; C496-F640 HydrophobicContact CB-CE2 4.5Å; C496-F640 HydrophobicContact CB-CZ 4.45Å; C496-F640 VanDerWaalsContact SG-CD2 3.54Å; C496-F640 WeakPolarHBondContact SG-CE2 3.29Å; C496-I646 HydrophobicContact CB-CD1 4.03Å
497G83.6Confident82.8Confident63 Ų6358.8 Ų58.865%0.64935%0.349SS*.THydrogen-bonded Turntrans75.29.6-179.300000115G495 S499G495-G497 PolarHBondContact O-N 3.11Å; G497-S499 VanDerWaalsContact C-N 3.25Å; G497-S499 PolarHBondContact O-N 3.31Å
498L87.9Confident81.9Confident26 Ų2658.9 Ų58.914%0.13635%0.35CS..  trans-82.664.9-177.7-53.8-179.9000111T493 C496 N511 I517 S582 A639 L643 I646T493-L498 HydrophobicContact CG2-CD1 4.07Å; C496-L498 VanDerWaalsContact C-N 3.27Å; C496-L498 HydrophobicContact CB-CD1 4.08Å; C496-L498 HydrophobicContact CB-CG 3.94Å; C496-L498 PolarHBondContact O-N 2.79Å; L498-N511 PolarHBondContact O-ND2 2.96Å; L498-I517 HydrophobicContact CD1-CD1 3.62Å; L498-S582 WeakPolarHBondContact O-CB 3.42Å; L498-A639 HydrophobicContact CD1-CB 3.9Å; L498-L643 HydrophobicContact CD1-CD1 3.88Å; L498-L643 HydrophobicContact CD2-CD1 4.25Å; L498-I646 HydrophobicContact CD1-CD1 4.4Å; L498-I646 HydrophobicContact CD2-CD1 4.22Å; L498-I646 HydrophobicContact CG-CD1 4.48Å
499S87.7Confident81.4Confident69 Ų6961 Ų6148%0.48336%0.359SS..PPolyproline II helixtrans-77.5157.4-174.7-55.70000113.5G497G497-S499 VanDerWaalsContact C-N 3.25Å; G497-S499 PolarHBondContact O-N 3.31Å
500E88.4Confident81.1Confident25 Ų2561 Ų6112%0.11736%0.359CS..PPolyproline II helixtrans-63.7148.9173.772.5-173.8-120.900112.8K509 R581 S582 N583E500-K509 WeakPolarHBondContact OE1-CD 3.38Å; E500-K509 VanDerWaalsContact OE1-CE 3.32Å; E500-K509 WeakPolarHBondContact OE1-CE 3.41Å; E500-K509 IonicContact OE1-NZ 2.68Å; E500-K509 PolarHBondContact OE1-NZ 3.45Å; E500-R581 IonicContact OE1-CZ 2.68Å; E500-R581 IonicContact OE1-NE 2.65Å; E500-R581 PolarHBondContact OE1-NE 2.96Å; E500-R581 IonicContact OE1-NH2 3.37Å; E500-R581 PolarHBondContact OE1-NH2 3.24Å; E500-R581 IonicContact OE2-CZ 2.72Å; E500-R581 IonicContact OE2-NE 3.89Å; E500-R581 PolarHBondContact OE2-NE 3.39Å; E500-R581 IonicContact OE2-NH2 2.62Å; E500-R581 PolarHBondContact OE2-NH2 3.07Å; E500-S582 WeakPolarHBondContact CG-O 3.37Å; E500-S582 PolarHBondContact N-O 3Å; E500-N583 HydrophobicContact CG-CB 4.37Å; E500-N583 PolarHBondContact OE2-ND2 3.08Å
501M85.7Confident80.9Confident74 Ų7461 Ų6137%0.36536%0.359SS..PPolyproline II helixtrans-75.8128.2178.5-64.4177.37100111.6I503 G510 L547M501-I503 HydrophobicContact CB-CD1 4.12Å; M501-I503 HydrophobicContact CB-CG1 4.39Å; M501-I503 HydrophobicContact CE-CD1 4.28Å; M501-I503 PolarHBondContact O-N 2.83Å; M501-G510 WeakPolarHBondContact CB-O 3.4Å; M501-G510 WeakPolarHBondContact CG-O 3.33Å; M501-G510 PolarHBondContact N-O 3.15Å; M501-L547 HydrophobicContact SD-CD1 4.01Å
502E69.1Low80.6Confident191 Ų19164.9 Ų64.989%0.89338%0.377SS*.  trans-81.5109.7168.6-66.4-175.7173.800110.1
503I68.8Low80.5Confident77 Ų7763.9 Ų63.940%0.39537%0.374SS..  trans-124.8146.4177.2-66.8162.1000107.8M501 D505 L543M501-I503 HydrophobicContact CB-CD1 4.12Å; M501-I503 HydrophobicContact CB-CG1 4.39Å; M501-I503 HydrophobicContact CE-CD1 4.28Å; M501-I503 PolarHBondContact O-N 2.83Å; I503-D505 HydrophobicContact CG2-CB 4.25Å; I503-D505 PolarHBondContact O-N 3.25Å; I503-D505 VanDerWaalsContact O-N 3.15Å; I503-L543 HydrophobicContact CD1-CD2 3.23Å
504A51.8Low80.5Confident109 Ų10963.8 Ų63.890%0.90137%0.373SS*.SBendtrans-68-9.9-176.100000114.5
505D53.1Low80.7Confident98 Ų9862.9 Ų62.952%0.52437%0.366SS..  trans-95.996175-167-11.1000108.3I503 Q507I503-D505 HydrophobicContact CG2-CB 4.25Å; I503-D505 PolarHBondContact O-N 3.25Å; I503-D505 VanDerWaalsContact O-N 3.15Å; D505-Q507 PolarHBondContact O-N 2.78Å; D505-Q507 VanDerWaalsContact O-N 3.09Å
506E57.2Low81.1Confident180 Ų18062.1 Ų62.184%0.84135%0.346SS*.THydrogen-bonded Turntrans-64.1-14.9-172.2-63.6-172.9157.900113.6S508E506-S508 PolarHBondContact O-N 3.44Å
507Q61.1Low81.5Confident173 Ų17361.7 Ų61.781%0.80834%0.344SS*.THydrogen-bonded Turntrans-79.7-9.2-173.2-60.9-156.7-9.800114.9D505D505-Q507 PolarHBondContact O-N 2.78Å; D505-Q507 VanDerWaalsContact O-N 3.09Å
508S77.8Confident82.1Confident23 Ų2358.7 Ų58.716%0.16131%0.313CS..  trans-142152.2176.3-144.70000113.6E506 N542 L543E506-S508 PolarHBondContact O-N 3.44Å; S508-N542 PolarHBondContact OG-N 3.47Å; S508-L543 PolarHBondContact OG-N 2.77Å; S508-L543 VanDerWaalsContact OG-N 3.12Å
509K87.9Confident82.5Confident49 Ų4957.8 Ų57.821%0.21331%0.309CS..  trans-125.9152.6-178.6-62.5-67.2-176.21550110.3E500 Y541 Q544 V580E500-K509 WeakPolarHBondContact OE1-CD 3.38Å; E500-K509 VanDerWaalsContact OE1-CE 3.32Å; E500-K509 WeakPolarHBondContact OE1-CE 3.41Å; E500-K509 IonicContact OE1-NZ 2.68Å; E500-K509 PolarHBondContact OE1-NZ 3.45Å; K509-Y541 HydrophobicContact CB-CD1 3.87Å; K509-Y541 HydrophobicContact CB-CD2 4.15Å; K509-Y541 HydrophobicContact CB-CE1 4.07Å; K509-Y541 HydrophobicContact CB-CE2 4.34Å; K509-Y541 HydrophobicContact CB-CG 3.9Å; K509-Y541 HydrophobicContact CG-CD1 4.17Å; K509-Y541 HydrophobicContact CG-CE1 3.93Å; K509-Y541 WeakPolarHBondContact O-CB 3.4Å; K509-Q544 PolarHBondContact O-N 3.43Å; K509-V580 HydrophobicContact CB-CG1 3.96Å
510G90.3Very high82.8Confident0 Ų057.5 Ų57.50%030%0.301CS..  trans-146.4153176.800000110.1M501M501-G510 WeakPolarHBondContact CB-O 3.4Å; M501-G510 WeakPolarHBondContact CG-O 3.33Å; M501-G510 PolarHBondContact N-O 3.15Å
511N94.1Very high83.2Confident1 Ų156.3 Ų56.31%0.00530%0.296CS..  trans-142.2103.9179.6-174.3-22.7000108.7L498 G513 E514 V515 Q544 V580L498-N511 PolarHBondContact O-ND2 2.96Å; N511-G513 VanDerWaalsContact C-N 3.26Å; N511-G513 PolarHBondContact O-N 3.05Å; N511-G513 PolarHBondContact OD1-N 3.5Å; N511-E514 HydrophobicContact CB-CB 4.22Å; N511-E514 HydrophobicContact CB-CG 4.2Å; N511-E514 PolarHBondContact ND2-OE1 3.39Å; N511-E514 PolarHBondContact O-N 3.36Å; N511-E514 PolarHBondContact OD1-N 3.1Å; N511-V515 WeakPolarHBondContact O-CG2 3.49Å; N511-V515 PolarHBondContact O-N 2.98Å; N511-V515 VanDerWaalsContact O-N 3.14Å; N511-Q544 PolarHBondContact O-NE2 3.18Å; N511-Q544 VanDerWaalsContact O-NE2 3.09Å; N511-Q544 PolarHBondContact O-OE1 3.41Å; N511-V580 HydrophobicContact CB-CG1 3.97Å; N511-V580 PolarHBondContact ND2-O 2.94Å
512Q92.6Very high83.7Confident81 Ų8152.8 Ų52.838%0.37928%0.278SS..Hα-helixtrans-64.2-31.4-178.3-173.458.854.100112.4V515 D516Q512-V515 WeakPolarHBondContact O-CB 3.29Å; Q512-V515 PolarHBondContact O-N 3.14Å; Q512-D516 PolarHBondContact NE2-OD1 3.25Å; Q512-D516 PolarHBondContact O-N 3.4Å
513G93.2Very high84.9Confident9 Ų948 Ų489%0.09326%0.255CS..Hα-helixtrans-64.5-4417700000112.3N511 D516 I517N511-G513 VanDerWaalsContact C-N 3.26Å; N511-G513 PolarHBondContact O-N 3.05Å; N511-G513 PolarHBondContact OD1-N 3.5Å; G513-D516 PolarHBondContact O-N 2.98Å; G513-I517 WeakPolarHBondContact O-CG1 3.45Å; G513-I517 PolarHBondContact O-N 2.92Å
514E95.8Very high86.1Confident0 Ų046.2 Ų46.20%025%0.249CC..Hα-helixtrans-64.2-40.4172.9-70.4-177.1-142.300112.1T493 N511 D516 I517 V518 S578 L579 V580 V611T493-E514 HydrophobicContact CG2-CG 4.23Å; N511-E514 HydrophobicContact CB-CB 4.22Å; N511-E514 HydrophobicContact CB-CG 4.2Å; N511-E514 PolarHBondContact ND2-OE1 3.39Å; N511-E514 PolarHBondContact O-N 3.36Å; N511-E514 PolarHBondContact OD1-N 3.1Å; E514-D516 PolarHBondContact O-N 2.8Å; E514-I517 PolarHBondContact O-N 2.83Å; E514-V518 VanDerWaalsContact O-CB 3.3Å; E514-V518 WeakPolarHBondContact O-CB 3.47Å; E514-V518 WeakPolarHBondContact O-CG2 3.32Å; E514-V518 PolarHBondContact O-N 3.45Å; E514-S578 WeakPolarHBondContact OE2-CB 3.49Å; E514-S578 PolarHBondContact OE2-OG 2.77Å; E514-L579 PolarHBondContact OE2-N 3.25Å; E514-V580 VanDerWaalsContact CD-N 3.32Å; E514-V580 WeakPolarHBondContact OE1-CA 3.38Å; E514-V580 PolarHBondContact OE1-N 3.13Å; E514-V580 WeakPolarHBondContact OE2-CA 3.39Å; E514-V580 PolarHBondContact OE2-N 2.71Å; E514-V611 HydrophobicContact CB-CG1 4.26Å; E514-V611 HydrophobicContact CG-CG1 3.94Å
515V95.6Very high88.2Confident0 Ų041 Ų410%021%0.206CC..Hα-helixtrans-57.4-35.1173.7172.10000111.4N511 Q512 S519 L547 L548 K551N511-V515 WeakPolarHBondContact O-CG2 3.49Å; N511-V515 PolarHBondContact O-N 2.98Å; N511-V515 VanDerWaalsContact O-N 3.14Å; Q512-V515 WeakPolarHBondContact O-CB 3.29Å; Q512-V515 PolarHBondContact O-N 3.14Å; V515-S519 VanDerWaalsContact O-CB 3.26Å; V515-S519 WeakPolarHBondContact O-CB 3.35Å; V515-S519 PolarHBondContact O-N 3.36Å; V515-S519 VanDerWaalsContact O-N 3.15Å; V515-L547 HydrophobicContact CG2-CB 3.84Å; V515-L548 HydrophobicContact CB-CD2 4.31Å; V515-L548 HydrophobicContact CG1-CD2 4.28Å; V515-L548 HydrophobicContact CG2-CD2 4.03Å; V515-L548 HydrophobicContact CG2-CG 4.09Å; V515-K551 HydrophobicContact CG1-CB 4.11Å; V515-K551 HydrophobicContact CG1-CD 3.67Å
516D94.5Very high90.2Very high48 Ų4837.9 Ų37.926%0.25719%0.191SC..Hα-helixtrans-72.8-45.6179.2-63.9-20.8000112.3Q512 G513 E514 S519 L520 K551 L643Q512-D516 PolarHBondContact NE2-OD1 3.25Å; Q512-D516 PolarHBondContact O-N 3.4Å; G513-D516 PolarHBondContact O-N 2.98Å; E514-D516 PolarHBondContact O-N 2.8Å; D516-S519 PolarHBondContact O-N 3.19Å; D516-L520 WeakPolarHBondContact O-CG 3.35Å; D516-L520 PolarHBondContact O-N 2.83Å; D516-K551 IonicContact OD1-NZ 3.6Å; D516-K551 PolarHBondContact OD1-NZ 3.27Å; D516-L643 HydrophobicContact CB-CD2 4.3Å
517I95.7Very high92Very high0 Ų035.6 Ų35.60%018%0.18CC..Hα-helixtrans-63.3-49.5175.5-65.4162.8000111.6I491 T493 L498 G513 E514 S519 L520 H521 V611 A639 Y642 L643I491-I517 HydrophobicContact CB-CG2 4.36Å; I491-I517 HydrophobicContact CD1-CG2 4.02Å; I491-I517 HydrophobicContact CG2-CG2 3.68Å; T493-I517 HydrophobicContact CG2-CD1 3.57Å; L498-I517 HydrophobicContact CD1-CD1 3.62Å; G513-I517 WeakPolarHBondContact O-CG1 3.45Å; G513-I517 PolarHBondContact O-N 2.92Å; E514-I517 PolarHBondContact O-N 2.83Å; I517-S519 PolarHBondContact O-N 3.48Å; I517-L520 WeakPolarHBondContact O-CA 3.48Å; I517-L520 WeakPolarHBondContact O-CB 3.38Å; I517-L520 PolarHBondContact O-N 2.93Å; I517-H521 PolarHBondContact O-N 3.21Å; I517-V611 HydrophobicContact CB-CG1 4.14Å; I517-V611 HydrophobicContact CD1-CG1 4.15Å; I517-V611 HydrophobicContact CG2-CG1 3.8Å; I517-V611 HydrophobicContact CG2-CG2 4.17Å; I517-A639 HydrophobicContact CD1-CB 3.49Å; I517-A639 VanDerWaalsContact CD1-CB 3.49Å; I517-A639 HydrophobicContact CG1-CB 4.4Å; I517-Y642 HydrophobicContact CG2-CD1 4.39Å; I517-Y642 HydrophobicContact CG2-CG 4.31Å; I517-L643 HydrophobicContact CD1-CD1 4.22Å; I517-L643 HydrophobicContact CG1-CD1 3.85Å; I517-L643 HydrophobicContact CG1-CG 4.28Å
518V96.6Very high93.6Very high0 Ų027.8 Ų27.80%015%0.145CC..Hα-helixtrans-56.3-41.1177.7168.40000110.4E514 L520 H521 I522 V537 L548 L552 V576 V611E514-V518 VanDerWaalsContact O-CB 3.3Å; E514-V518 WeakPolarHBondContact O-CB 3.47Å; E514-V518 WeakPolarHBondContact O-CG2 3.32Å; E514-V518 PolarHBondContact O-N 3.45Å; V518-L520 VanDerWaalsContact C-N 3.29Å; V518-L520 PolarHBondContact O-N 2.79Å; V518-H521 PolarHBondContact O-N 3.48Å; V518-I522 HydrophobicContact CG1-CD1 3.56Å; V518-I522 HydrophobicContact CG1-CG1 4.43Å; V518-I522 WeakPolarHBondContact O-CB 3.34Å; V518-I522 VanDerWaalsContact O-CD1 3.32Å; V518-I522 WeakPolarHBondContact O-CD1 3.49Å; V518-I522 WeakPolarHBondContact O-CG1 3.5Å; V518-I522 PolarHBondContact O-N 3.11Å; V518-V537 HydrophobicContact CG1-CG1 3.72Å; V518-L548 HydrophobicContact CB-CD2 4.06Å; V518-L548 HydrophobicContact CG1-CD2 3.69Å; V518-L552 HydrophobicContact CG1-CD1 4.39Å; V518-V576 HydrophobicContact CB-CG1 4.4Å; V518-V576 HydrophobicContact CG1-CG1 3.97Å; V518-V576 HydrophobicContact CG2-CG1 3.93Å; V518-V611 HydrophobicContact CG2-CB 4.23Å; V518-V611 HydrophobicContact CG2-CG2 3.71Å
519S95.6Very high94.4Very high7 Ų728.1 Ų28.15%0.04915%0.152CC..Hα-helixtrans-67.8-24.4176.41790000114.4V515 D516 I517V515-S519 VanDerWaalsContact O-CB 3.26Å; V515-S519 WeakPolarHBondContact O-CB 3.35Å; V515-S519 PolarHBondContact O-N 3.36Å; V515-S519 VanDerWaalsContact O-N 3.15Å; D516-S519 PolarHBondContact O-N 3.19Å; I517-S519 PolarHBondContact O-N 3.48Å
520L94.7Very high94.8Very high63 Ų6326 Ų2633%0.3314%0.143SC..Hα-helixtrans-81.3-43.9174-70.2167.8000110.7D516 I517 V518 I522 K523 S524 Y642 L643D516-L520 WeakPolarHBondContact O-CG 3.35Å; D516-L520 PolarHBondContact O-N 2.83Å; I517-L520 WeakPolarHBondContact O-CA 3.48Å; I517-L520 WeakPolarHBondContact O-CB 3.38Å; I517-L520 PolarHBondContact O-N 2.93Å; V518-L520 VanDerWaalsContact C-N 3.29Å; V518-L520 PolarHBondContact O-N 2.79Å; L520-I522 PolarHBondContact O-N 2.94Å; L520-K523 WeakPolarHBondContact O-CA 3.22Å; L520-K523 VanDerWaalsContact O-CB 3.26Å; L520-K523 WeakPolarHBondContact O-CB 3.34Å; L520-K523 PolarHBondContact O-N 2.85Å; L520-S524 PolarHBondContact O-N 2.74Å; L520-S524 PolarHBondContact O-OG 2.93Å; L520-Y642 HydrophobicContact CB-CD1 3.98Å; L520-Y642 HydrophobicContact CD1-CD1 4.48Å; L520-Y642 VanDerWaalsContact CD1-O 3.3Å; L520-Y642 WeakPolarHBondContact CD1-O 3.36Å; L520-L643 HydrophobicContact CD1-CD2 4.01Å
521H95.9Very high95.1Very high0 Ų031.2 Ų31.20%017%0.166CC..Hα-helixtrans-61.4-43.8177.4-169.353.1000112.6L489 I491 I517 V518 K523 S524 L525 H607 A609 Y642L489-H521 WeakPolarHBondContact CD2-CE1 3.39Å; I491-H521 HydrophobicContact CD1-CB 4.36Å; I517-H521 PolarHBondContact O-N 3.21Å; V518-H521 PolarHBondContact O-N 3.48Å; H521-K523 PolarHBondContact O-N 3.47Å; H521-S524 WeakPolarHBondContact O-CB 3.17Å; H521-S524 PolarHBondContact O-N 2.8Å; H521-S524 VanDerWaalsContact O-N 3.14Å; H521-L525 WeakPolarHBondContact O-CG 3.39Å; H521-L525 PolarHBondContact O-N 2.83Å; H521-H607 AromaticContact CE1-NE2 3.85Å; H521-H607 AromaticContact NE2-CE1 3.95Å; H521-H607 AromaticContact NE2-NE2 3.12Å; H521-H607 PolarHBondContact NE2-NE2 3.37Å; H521-H607 VanDerWaalsContact NE2-NE2 3.12Å; H521-A609 WeakPolarHBondContact NE2-CB 3.34Å; H521-Y642 HydrophobicContact CB-CE1 4.43Å
522I95.8Very high95Very high0 Ų031.9 Ų31.90%017%0.172CC..Hα-helixtrans-61.2-35.2174.1-66.9162.4000111.3V518 L520 T526 V537 L552 M559 V576V518-I522 HydrophobicContact CG1-CD1 3.56Å; V518-I522 HydrophobicContact CG1-CG1 4.43Å; V518-I522 WeakPolarHBondContact O-CB 3.34Å; V518-I522 VanDerWaalsContact O-CD1 3.32Å; V518-I522 WeakPolarHBondContact O-CD1 3.49Å; V518-I522 WeakPolarHBondContact O-CG1 3.5Å; V518-I522 PolarHBondContact O-N 3.11Å; L520-I522 PolarHBondContact O-N 2.94Å; I522-T526 HydrophobicContact CG2-CG2 4.41Å; I522-T526 WeakPolarHBondContact O-CB 3.27Å; I522-T526 WeakPolarHBondContact O-CG2 3.46Å; I522-T526 PolarHBondContact O-N 3.13Å; I522-T526 PolarHBondContact O-OG1 3.41Å; I522-V537 HydrophobicContact CD1-CG2 3.43Å; I522-V537 VanDerWaalsContact CD1-CG2 3.43Å; I522-V537 HydrophobicContact CG1-CG2 4.45Å; I522-L552 HydrophobicContact CD1-CD1 3.65Å; I522-L552 HydrophobicContact CD1-CD2 4.24Å; I522-M559 HydrophobicContact CD1-CE 3.92Å; I522-M559 HydrophobicContact CD1-SD 4.01Å; I522-M559 HydrophobicContact CG1-SD 4.39Å; I522-M559 HydrophobicContact CG2-CE 4.25Å; I522-M559 HydrophobicContact CG2-SD 3.78Å; I522-V576 HydrophobicContact CG1-CG2 4.26Å
523K94.1Very high95.1Very high90 Ų9032.8 Ų32.839%0.39117%0.174SC..Hα-helixtrans-63.6-48.3173.9-168.1-171.7176.2-96.70110.4L520 H521 L525 T526 E527L520-K523 WeakPolarHBondContact O-CA 3.22Å; L520-K523 VanDerWaalsContact O-CB 3.26Å; L520-K523 WeakPolarHBondContact O-CB 3.34Å; L520-K523 PolarHBondContact O-N 2.85Å; H521-K523 PolarHBondContact O-N 3.47Å; K523-L525 PolarHBondContact O-N 2.94Å; K523-T526 PolarHBondContact O-N 2.91Å; K523-T526 PolarHBondContact O-OG1 3.35Å; K523-T526 VanDerWaalsContact O-OG1 3.11Å; K523-E527 WeakPolarHBondContact CE-OE1 3.36Å; K523-E527 HydrophobicContact CG-CG 4.28Å; K523-E527 IonicContact NZ-OE1 2.69Å; K523-E527 PolarHBondContact NZ-OE1 3.08Å; K523-E527 IonicContact NZ-OE2 2.63Å; K523-E527 PolarHBondContact NZ-OE2 2.88Å; K523-E527 WeakPolarHBondContact O-CB 3.49Å; K523-E527 WeakPolarHBondContact O-CG 3.19Å; K523-E527 PolarHBondContact O-N 3Å
524S94.4Very high95.2Very high39 Ų3934.4 Ų34.427%0.27318%0.181SC..Hα-helixtrans-57-47176-57.20000112.3L520 H521 T526 E527 A528L520-S524 PolarHBondContact O-N 2.74Å; L520-S524 PolarHBondContact O-OG 2.93Å; H521-S524 WeakPolarHBondContact O-CB 3.17Å; H521-S524 PolarHBondContact O-N 2.8Å; H521-S524 VanDerWaalsContact O-N 3.14Å; S524-T526 PolarHBondContact O-N 2.74Å; S524-E527 PolarHBondContact O-N 2.94Å; S524-A528 VanDerWaalsContact O-CB 3.3Å; S524-A528 WeakPolarHBondContact O-CB 3.32Å; S524-A528 PolarHBondContact O-N 3.26Å
525L95.8Very high95.2Very high0 Ų034.4 Ų34.40%018%0.181CC..Hα-helixtrans-62-42178.2-67.1179.1000112.6L472 E483 H521 K523 A528 G529 V530 I535 A574L472-L525 HydrophobicContact CD1-CD2 3.85Å; E483-L525 HydrophobicContact CB-CD2 4.01Å; H521-L525 WeakPolarHBondContact O-CG 3.39Å; H521-L525 PolarHBondContact O-N 2.83Å; K523-L525 PolarHBondContact O-N 2.94Å; L525-A528 PolarHBondContact O-N 3.32Å; L525-G529 PolarHBondContact O-N 3.39Å; L525-V530 HydrophobicContact CB-CB 4.3Å; L525-V530 HydrophobicContact CB-CG2 4.36Å; L525-V530 VanDerWaalsContact O-CB 3.25Å; L525-V530 WeakPolarHBondContact O-CB 3.47Å; L525-V530 WeakPolarHBondContact O-CG2 3.37Å; L525-V530 PolarHBondContact O-N 2.88Å; L525-I535 HydrophobicContact CB-CD1 4.1Å; L525-I535 HydrophobicContact CD1-CD1 4.44Å; L525-A574 HydrophobicContact CD1-CB 4.31Å
526T95Very high95.2Very high33 Ų3334.4 Ų34.420%0.20218%0.181CC..Hα-helixtrans-75.1-34.5-18052.20000113I522 K523 S524 A528 G529 I535I522-T526 HydrophobicContact CG2-CG2 4.41Å; I522-T526 WeakPolarHBondContact O-CB 3.27Å; I522-T526 WeakPolarHBondContact O-CG2 3.46Å; I522-T526 PolarHBondContact O-N 3.13Å; I522-T526 PolarHBondContact O-OG1 3.41Å; K523-T526 PolarHBondContact O-N 2.91Å; K523-T526 PolarHBondContact O-OG1 3.35Å; K523-T526 VanDerWaalsContact O-OG1 3.11Å; S524-T526 PolarHBondContact O-N 2.74Å; T526-A528 VanDerWaalsContact C-N 3.3Å; T526-G529 PolarHBondContact O-N 2.95Å; T526-I535 HydrophobicContact CG2-CD1 3.88Å
527E94.9Very high95.4Very high131 Ų13132.1 Ų32.161%0.61217%0.168SC*.Hα-helixtrans-67.8-30.2170.8-72.9-176.6148.200112.1K523 S524 G529K523-E527 WeakPolarHBondContact CE-OE1 3.36Å; K523-E527 HydrophobicContact CG-CG 4.28Å; K523-E527 IonicContact NZ-OE1 2.69Å; K523-E527 PolarHBondContact NZ-OE1 3.08Å; K523-E527 IonicContact NZ-OE2 2.63Å; K523-E527 PolarHBondContact NZ-OE2 2.88Å; K523-E527 WeakPolarHBondContact O-CB 3.49Å; K523-E527 WeakPolarHBondContact O-CG 3.19Å; K523-E527 PolarHBondContact O-N 3Å; S524-E527 PolarHBondContact O-N 2.94Å; E527-G529 PolarHBondContact O-N 2.87Å
528A95.1Very high95.4Very high9 Ų932.1 Ų32.17%0.07417%0.168CC..THydrogen-bonded Turntrans-75.90.3169.100000113.9V478 A479 V481 T484 S524 L525 T526V478-A528 CarbonylContact C-O 3.59Å; V478-A528 WeakPolarHBondContact CA-O 3.49Å; A479-A528 PolarHBondContact N-O 3.45Å; V481-A528 HydrophobicContact CG2-CB 3.7Å; T484-A528 HydrophobicContact CG2-CB 3.93Å; S524-A528 VanDerWaalsContact O-CB 3.3Å; S524-A528 WeakPolarHBondContact O-CB 3.32Å; S524-A528 PolarHBondContact O-N 3.26Å; L525-A528 PolarHBondContact O-N 3.32Å; T526-A528 VanDerWaalsContact C-N 3.3Å
529G95.4Very high95.2Very high30 Ų3032.1 Ų32.131%0.30917%0.168SC..THydrogen-bonded Turntrans95.22.1174.600000116L525 T526 E527 K531L525-G529 PolarHBondContact O-N 3.39Å; T526-G529 PolarHBondContact O-N 2.95Å; E527-G529 PolarHBondContact O-N 2.87Å; G529-K531 PolarHBondContact O-N 3.31Å
530V96Very high94.9Very high5 Ų532 Ų323%0.0317%0.168CC..  trans-69125.8173.8-1730000109.3L472 V478 T484 L525 I535L472-V530 HydrophobicContact CD1-CG2 4.37Å; V478-V530 HydrophobicContact CG1-CG2 3.84Å; V478-V530 HydrophobicContact CG2-CG2 3.95Å; T484-V530 HydrophobicContact CG2-CG2 4.37Å; L525-V530 HydrophobicContact CB-CB 4.3Å; L525-V530 HydrophobicContact CB-CG2 4.36Å; L525-V530 VanDerWaalsContact O-CB 3.25Å; L525-V530 WeakPolarHBondContact O-CB 3.47Å; L525-V530 WeakPolarHBondContact O-CG2 3.37Å; L525-V530 PolarHBondContact O-N 2.88Å; V530-I535 HydrophobicContact CB-CD1 4.34Å; V530-I535 HydrophobicContact CG1-CD1 3.98Å; V530-I535 HydrophobicContact CG1-CG1 3.76Å
531K95.5Very high94.6Very high109 Ų10929.7 Ų29.747%0.47416%0.155SC..  trans-74.5136.5-175-60.6167.4-173.5162.50110.3G529 K533 D534G529-K531 PolarHBondContact O-N 3.31Å; K531-K533 HydrophobicContact CB-CG 4.08Å; K531-K533 PolarHBondContact O-N 3.46Å; K531-K533 VanDerWaalsContact O-N 3.13Å; K531-D534 WeakPolarHBondContact CB-OD2 3.4Å; K531-D534 WeakPolarHBondContact O-CB 3.48Å; K531-D534 PolarHBondContact O-N 3.49Å
532A93.3Very high94Very high16 Ų1634.6 Ų34.613%0.13218%0.181CC..G310 helixtrans-53.4-37.5-177.900000114D534 I535 H556 M559A532-D534 PolarHBondContact O-N 3.49Å; A532-I535 PolarHBondContact O-N 2.89Å; A532-H556 HydrophobicContact CB-CB 4.06Å; A532-M559 HydrophobicContact CB-CB 4.36Å; A532-M559 WeakPolarHBondContact O-CA 3.46Å
533K93.6Very high93.6Very high99 Ų9936.8 Ų36.843%0.4319%0.192SC..G310 helixtrans-63-23.4175.664.8166.9-162.5168.80114.8K531 E558 K572K531-K533 HydrophobicContact CB-CG 4.08Å; K531-K533 PolarHBondContact O-N 3.46Å; K531-K533 VanDerWaalsContact O-N 3.13Å; K533-E558 HydrophobicContact CB-CB 4.12Å; K533-K572 WeakPolarHBondContact O-CD 3.22Å; K533-K572 WeakPolarHBondContact O-CE 3.23Å; K533-K572 PolarHBondContact O-NZ 2.96Å
534D96Very high93.5Very high43 Ų4332.5 Ų32.523%0.2317%0.174CC..G310 helixtrans-95.30.7-176.8-58.7-36.5000111.3K531 A532 E573 A574K531-D534 WeakPolarHBondContact CB-OD2 3.4Å; K531-D534 WeakPolarHBondContact O-CB 3.48Å; K531-D534 PolarHBondContact O-N 3.49Å; A532-D534 PolarHBondContact O-N 3.49Å; D534-E573 HydrophobicContact CB-CB 4.26Å; D534-E573 HydrophobicContact CB-CG 4.07Å; D534-E573 PolarHBondContact O-N 3.3Å; D534-E573 VanDerWaalsContact O-N 3.09Å; D534-A574 PolarHBondContact O-N 3.38Å; D534-A574 VanDerWaalsContact O-N 3.14Å
535I96.5Very high93.2Very high0 Ų030.7 Ų30.70%016%0.161CC..EExtended strand (participates in β ladder)trans-106143.6173.8-53.1174.9000109.3L525 T526 V530 A532 M559 A574L525-I535 HydrophobicContact CB-CD1 4.1Å; L525-I535 HydrophobicContact CD1-CD1 4.44Å; T526-I535 HydrophobicContact CG2-CD1 3.88Å; V530-I535 HydrophobicContact CB-CD1 4.34Å; V530-I535 HydrophobicContact CG1-CD1 3.98Å; V530-I535 HydrophobicContact CG1-CG1 3.76Å; A532-I535 PolarHBondContact O-N 2.89Å; I535-M559 HydrophobicContact CB-CG 4.37Å; I535-M559 HydrophobicContact CB-SD 4.33Å; I535-M559 HydrophobicContact CG2-CG 4.45Å; I535-M559 HydrophobicContact CG2-SD 4.01Å; I535-A574 WeakPolarHBondContact CA-O 3.44Å; I535-A574 HydrophobicContact CG1-CB 4.26Å
536A95.6Very high92.7Very high0 Ų034 Ų340%018%0.179CC..EExtended strand (participates in β ladder)trans-128151.6160.700000112.4E560 F567 K572 A574 V575 V576A536-E560 CarbonylContact C-O 3.18Å; A536-E560 VanDerWaalsContact CA-O 3.32Å; A536-E560 WeakPolarHBondContact CA-O 3.45Å; A536-E560 HydrophobicContact CB-CB 4.37Å; A536-F567 HydrophobicContact CB-CD2 4.42Å; A536-F567 HydrophobicContact CB-CE1 4.2Å; A536-F567 HydrophobicContact CB-CE2 3.45Å; A536-F567 VanDerWaalsContact CB-CE2 3.45Å; A536-F567 HydrophobicContact CB-CZ 3.32Å; A536-K572 HydrophobicContact CB-CB 4.32Å; A536-K572 HydrophobicContact CB-CG 3.62Å; A536-A574 PolarHBondContact N-O 3.44Å; A536-V575 CarbonylContact O-C 3.58Å; A536-V575 WeakPolarHBondContact O-CA 3.3Å; A536-V576 PolarHBondContact O-N 3.07Å
537V96.7Very high92.3Very high0 Ų033.5 Ų33.50%018%0.175CC..EExtended strand (participates in β ladder)trans-114.5124.9171.1-165.50000108.7V518 I522 L548 M559 E560 I561 K562 V576V518-V537 HydrophobicContact CG1-CG1 3.72Å; I522-V537 HydrophobicContact CD1-CG2 3.43Å; I522-V537 VanDerWaalsContact CD1-CG2 3.43Å; I522-V537 HydrophobicContact CG1-CG2 4.45Å; V537-L548 HydrophobicContact CG1-CD1 3.71Å; V537-L548 HydrophobicContact CG1-CD2 4.23Å; V537-L548 HydrophobicContact CG1-CG 4.5Å; V537-M559 HydrophobicContact CG2-CE 3.88Å; V537-M559 HydrophobicContact CG2-SD 3.92Å; V537-E560 PolarHBondContact N-O 3.11Å; V537-I561 HydrophobicContact CB-CG1 4.16Å; V537-I561 HydrophobicContact CB-CG2 4.27Å; V537-I561 HydrophobicContact CG2-CG1 4.17Å; V537-I561 WeakPolarHBondContact O-CA 3.2Å; V537-K562 PolarHBondContact O-N 2.95Å; V537-K562 VanDerWaalsContact O-N 3.08Å; V537-V576 CarbonylContact C-O 3.56Å; V537-V576 WeakPolarHBondContact CA-O 3.23Å
538I95.7Very high92.1Very high0 Ų027.3 Ų27.30%015%0.146CC..EExtended strand (participates in β ladder)trans-119.7134.4-176.7-57.1-177000108.6K562 V564 F567 V575 V576 L577 S578 A600 R603I538-K562 WeakPolarHBondContact CA-O 3.47Å; I538-V564 HydrophobicContact CG2-CB 4.26Å; I538-V564 HydrophobicContact CG2-CG2 3.56Å; I538-F567 HydrophobicContact CD1-CB 4.18Å; I538-F567 HydrophobicContact CD1-CD1 3.9Å; I538-F567 HydrophobicContact CD1-CD2 4.43Å; I538-F567 HydrophobicContact CD1-CE1 4.47Å; I538-F567 HydrophobicContact CD1-CG 3.89Å; I538-F567 HydrophobicContact CG1-CD2 4.41Å; I538-F567 HydrophobicContact CG1-CG 4.31Å; I538-V575 HydrophobicContact CD1-CG1 3.74Å; I538-V575 HydrophobicContact CG1-CG1 4.07Å; I538-V576 PolarHBondContact N-O 3.3Å; I538-L577 HydrophobicContact CB-CD1 4.21Å; I538-L577 HydrophobicContact CG2-CD1 4.06Å; I538-L577 WeakPolarHBondContact O-CA 3.42Å; I538-L577 WeakPolarHBondContact O-CD1 3.43Å; I538-S578 PolarHBondContact O-N 3.46Å; I538-A600 HydrophobicContact CG2-CB 4.35Å; I538-R603 HydrophobicContact CD1-CB 3.99Å; I538-R603 HydrophobicContact CD1-CG 3.74Å
539A94Very high91.8Very high0 Ų031.6 Ų31.60%016%0.16CC..  trans-140.7141.8170.100000110.2Y541 Q544 V545 L548 K562 S563A539-Y541 VanDerWaalsContact C-N 3.25Å; A539-Y541 PolarHBondContact O-N 3.49Å; A539-Q544 HydrophobicContact CB-CB 3.95Å; A539-Q544 HydrophobicContact CB-CG 3.72Å; A539-V545 HydrophobicContact CB-CG2 3.99Å; A539-L548 HydrophobicContact CB-CD1 4.16Å; A539-K562 PolarHBondContact N-O 3.48Å; A539-S563 VanDerWaalsContact O-CA 3.29Å; A539-S563 WeakPolarHBondContact O-CA 3.03Å
540P89.4Confident91.3Very high6 Ų637.6 Ų37.64%0.03918%0.18CC..SBendtrans-66.8-25.5-179.2-2.17.8000113.6S578 F590 L591P540-S578 WeakPolarHBondContact CD-O 3.45Å; P540-F590 HydrophobicContact CB-CD1 4.19Å; P540-F590 HydrophobicContact CB-CE1 4.43Å; P540-F590 WeakPolarHBondContact O-CE1 3.34Å; P540-L591 HydrophobicContact CB-CD2 4.13Å; P540-L591 HydrophobicContact CG-CD2 3.32Å; P540-L591 HydrophobicContact CG-CG 4.43Å
541Y87.4Confident91Very high14 Ų1440.5 Ų40.56%0.05519%0.192CC..SBendtrans-106129-172.2-64.2-82.4000112.4K509 A539 L543 Q544 V545 V580 R581 V588 F590 L591K509-Y541 HydrophobicContact CB-CD1 3.87Å; K509-Y541 HydrophobicContact CB-CD2 4.15Å; K509-Y541 HydrophobicContact CB-CE1 4.07Å; K509-Y541 HydrophobicContact CB-CE2 4.34Å; K509-Y541 HydrophobicContact CB-CG 3.9Å; K509-Y541 HydrophobicContact CG-CD1 4.17Å; K509-Y541 HydrophobicContact CG-CE1 3.93Å; K509-Y541 WeakPolarHBondContact O-CB 3.4Å; A539-Y541 VanDerWaalsContact C-N 3.25Å; A539-Y541 PolarHBondContact O-N 3.49Å; Y541-L543 VanDerWaalsContact C-N 3.31Å; Y541-L543 PolarHBondContact O-N 3.02Å; Y541-Q544 WeakPolarHBondContact O-CB 3.36Å; Y541-Q544 PolarHBondContact O-N 2.8Å; Y541-Q544 VanDerWaalsContact O-N 3.07Å; Y541-V545 WeakPolarHBondContact O-CG2 3.38Å; Y541-V545 PolarHBondContact O-N 3.38Å; Y541-V545 VanDerWaalsContact O-N 3.1Å; Y541-V580 HydrophobicContact CD2-CB 3.8Å; Y541-V580 HydrophobicContact CD2-CG1 4.22Å; Y541-V580 HydrophobicContact CD2-CG2 3.87Å; Y541-V580 HydrophobicContact CE2-CB 4.28Å; Y541-R581 HydrophobicContact CE2-CG 3.94Å; Y541-R581 WeakPolarHBondContact OH-CD 3.36Å; Y541-V588 PolarHBondContact OH-O 3.45Å; Y541-F590 HydrophobicContact CE1-CB 3.98Å; Y541-F590 HydrophobicContact CE1-CD1 4.44Å; Y541-L591 HydrophobicContact CE2-CG 4.45Å
542N84.6Confident90.7Very high102 Ų10235.4 Ų35.455%0.54517%0.17SC..Hα-helixtrans-57.8-39.3-178.6-68.6-34.7000113.2S508 Q544 V545 D546S508-N542 PolarHBondContact OG-N 3.47Å; N542-Q544 PolarHBondContact O-N 2.81Å; N542-V545 WeakPolarHBondContact O-CB 3.45Å; N542-V545 PolarHBondContact O-N 2.95Å; N542-D546 PolarHBondContact O-N 3.05Å
543L86.6Confident90.2Very high46 Ų4637 Ų3724%0.24118%0.181CC..Hα-helixtrans-60.4-43.2175.617366.3000112.1I503 S508 Y541 V545 D546 L547I503-L543 HydrophobicContact CD1-CD2 3.23Å; S508-L543 PolarHBondContact OG-N 2.77Å; S508-L543 VanDerWaalsContact OG-N 3.12Å; Y541-L543 VanDerWaalsContact C-N 3.31Å; Y541-L543 PolarHBondContact O-N 3.02Å; L543-V545 VanDerWaalsContact C-N 3.33Å; L543-V545 PolarHBondContact O-N 3.42Å; L543-D546 PolarHBondContact O-N 3.15Å; L543-L547 HydrophobicContact CD1-CG 4.36Å; L543-L547 HydrophobicContact CG-CD1 4.31Å; L543-L547 WeakPolarHBondContact O-CG 3.35Å; L543-L547 PolarHBondContact O-N 3.31Å
544Q91.1Very high89.6Confident0 Ų036.9 Ų36.90%020%0.198CC..Hα-helixtrans-62.1-42.4175.4-172.874.8-20.800111.6K509 N511 A539 Y541 N542 D546 L547 L548 S578 V580K509-Q544 PolarHBondContact O-N 3.43Å; N511-Q544 PolarHBondContact O-NE2 3.18Å; N511-Q544 VanDerWaalsContact O-NE2 3.09Å; N511-Q544 PolarHBondContact O-OE1 3.41Å; A539-Q544 HydrophobicContact CB-CB 3.95Å; A539-Q544 HydrophobicContact CB-CG 3.72Å; Y541-Q544 WeakPolarHBondContact O-CB 3.36Å; Y541-Q544 PolarHBondContact O-N 2.8Å; Y541-Q544 VanDerWaalsContact O-N 3.07Å; N542-Q544 PolarHBondContact O-N 2.81Å; Q544-D546 VanDerWaalsContact C-N 3.25Å; Q544-D546 PolarHBondContact O-N 3.26Å; Q544-L547 PolarHBondContact O-N 2.78Å; Q544-L548 HydrophobicContact CG-CD1 3.97Å; Q544-L548 HydrophobicContact CG-CG 4.39Å; Q544-L548 WeakPolarHBondContact O-CB 3.44Å; Q544-L548 WeakPolarHBondContact O-CD1 3.49Å; Q544-L548 VanDerWaalsContact O-CG 3.23Å; Q544-L548 WeakPolarHBondContact O-CG 3.42Å; Q544-L548 PolarHBondContact O-N 3.4Å; Q544-S578 PolarHBondContact NE2-OG 2.69Å; Q544-V580 HydrophobicContact CB-CG1 4.44Å; Q544-V580 HydrophobicContact CB-CG2 3.64Å; Q544-V580 HydrophobicContact CG-CG2 3.49Å; Q544-V580 VanDerWaalsContact CG-CG2 3.49Å
545V88.6Confident89.1Confident2 Ų242.7 Ų42.71%0.01222%0.217CC..Hα-helixtrans-57.3-40.8175.2174.70000110.9A539 Y541 N542 L543 R549 I561 K562A539-V545 HydrophobicContact CB-CG2 3.99Å; Y541-V545 WeakPolarHBondContact O-CG2 3.38Å; Y541-V545 PolarHBondContact O-N 3.38Å; Y541-V545 VanDerWaalsContact O-N 3.1Å; N542-V545 WeakPolarHBondContact O-CB 3.45Å; N542-V545 PolarHBondContact O-N 2.95Å; L543-V545 VanDerWaalsContact C-N 3.33Å; L543-V545 PolarHBondContact O-N 3.42Å; V545-R549 WeakPolarHBondContact O-CB 3.32Å; V545-R549 VanDerWaalsContact O-CG 3.24Å; V545-R549 WeakPolarHBondContact O-CG 3.36Å; V545-R549 PolarHBondContact O-N 3.18Å; V545-I561 HydrophobicContact CG1-CG2 4.25Å; V545-K562 VanDerWaalsContact CG2-C 3.48Å
546D85.1Confident88.6Confident68 Ų6844.3 Ų44.336%0.36422%0.224SC..Hα-helixtrans-74.1-37.2179.1-68.4-26000113.1N542 L543 Q544 R549 Q550N542-D546 PolarHBondContact O-N 3.05Å; L543-D546 PolarHBondContact O-N 3.15Å; Q544-D546 VanDerWaalsContact C-N 3.25Å; Q544-D546 PolarHBondContact O-N 3.26Å; D546-R549 PolarHBondContact O-N 3.06Å; D546-R549 IonicContact OD1-CZ 3.18Å; D546-R549 IonicContact OD1-NH1 2.71Å; D546-R549 PolarHBondContact OD1-NH1 3.25Å; D546-Q550 VanDerWaalsContact O-CG 3.29Å; D546-Q550 WeakPolarHBondContact O-CG 3.25Å; D546-Q550 PolarHBondContact O-N 3.22Å
547L88.1Confident87.8Confident24 Ų2449.6 Ų49.613%0.12626%0.259CS..Hα-helixtrans-62-44.2171.1-68.2172000111.5M501 V515 L543 Q544 Q550 K551M501-L547 HydrophobicContact SD-CD1 4.01Å; V515-L547 HydrophobicContact CG2-CB 3.84Å; L543-L547 HydrophobicContact CD1-CG 4.36Å; L543-L547 HydrophobicContact CG-CD1 4.31Å; L543-L547 WeakPolarHBondContact O-CG 3.35Å; L543-L547 PolarHBondContact O-N 3.31Å; Q544-L547 PolarHBondContact O-N 2.78Å; L547-Q550 PolarHBondContact O-N 2.96Å; L547-K551 PolarHBondContact O-N 2.85Å; L547-K551 VanDerWaalsContact O-N 3.15Å
548L90.2Very high87.2Confident0 Ų055.9 Ų55.90%029%0.288CS..Hα-helixtrans-60.4-45.6174.8-73.2165.6000111.3V515 V518 V537 A539 Q544 K551 L552 I561V515-L548 HydrophobicContact CB-CD2 4.31Å; V515-L548 HydrophobicContact CG1-CD2 4.28Å; V515-L548 HydrophobicContact CG2-CD2 4.03Å; V515-L548 HydrophobicContact CG2-CG 4.09Å; V518-L548 HydrophobicContact CB-CD2 4.06Å; V518-L548 HydrophobicContact CG1-CD2 3.69Å; V537-L548 HydrophobicContact CG1-CD1 3.71Å; V537-L548 HydrophobicContact CG1-CD2 4.23Å; V537-L548 HydrophobicContact CG1-CG 4.5Å; A539-L548 HydrophobicContact CB-CD1 4.16Å; Q544-L548 HydrophobicContact CG-CD1 3.97Å; Q544-L548 HydrophobicContact CG-CG 4.39Å; Q544-L548 WeakPolarHBondContact O-CB 3.44Å; Q544-L548 WeakPolarHBondContact O-CD1 3.49Å; Q544-L548 VanDerWaalsContact O-CG 3.23Å; Q544-L548 WeakPolarHBondContact O-CG 3.42Å; Q544-L548 PolarHBondContact O-N 3.4Å; L548-K551 PolarHBondContact O-N 2.89Å; L548-L552 HydrophobicContact CB-CD1 4.45Å; L548-L552 HydrophobicContact CD2-CD1 4.04Å; L548-L552 VanDerWaalsContact O-CB 3.25Å; L548-L552 WeakPolarHBondContact O-CB 3.49Å; L548-L552 WeakPolarHBondContact O-CG 3.2Å; L548-L552 PolarHBondContact O-N 2.93Å; L548-I561 HydrophobicContact CB-CG2 3.67Å; L548-I561 HydrophobicContact CD1-CG2 4.38Å
549R87.8Confident86.9Confident99 Ų9956.3 Ų56.337%0.37429%0.29SS..Hα-helixtrans-59.8-47.6175.4-75.7167-177.6160.8-1.8112.4V545 D546 K551 L552 S553 I561V545-R549 WeakPolarHBondContact O-CB 3.32Å; V545-R549 VanDerWaalsContact O-CG 3.24Å; V545-R549 WeakPolarHBondContact O-CG 3.36Å; V545-R549 PolarHBondContact O-N 3.18Å; D546-R549 PolarHBondContact O-N 3.06Å; D546-R549 IonicContact OD1-CZ 3.18Å; D546-R549 IonicContact OD1-NH1 2.71Å; D546-R549 PolarHBondContact OD1-NH1 3.25Å; R549-K551 PolarHBondContact O-N 3Å; R549-L552 PolarHBondContact O-N 3.08Å; R549-S553 WeakPolarHBondContact CA-OG 3.31Å; R549-S553 VanDerWaalsContact O-CB 3.23Å; R549-S553 WeakPolarHBondContact O-CB 3.47Å; R549-S553 PolarHBondContact O-N 2.89Å; R549-S553 PolarHBondContact O-OG 2.98Å; R549-I561 HydrophobicContact CG-CB 3.95Å; R549-I561 HydrophobicContact CG-CD1 4.29Å; R549-I561 HydrophobicContact CG-CG2 3.93Å; R549-I561 PolarHBondContact NE-O 2.96Å; R549-I561 VanDerWaalsContact NE-O 3.13Å; R549-I561 PolarHBondContact NH2-O 3.43Å
550Q86.4Confident86.6Confident156 Ų15658.1 Ų58.173%0.72930%0.299SS*.Hα-helixtrans-57-38.1178.6-74.4174.129.600111.9D546 L547D546-Q550 VanDerWaalsContact O-CG 3.29Å; D546-Q550 WeakPolarHBondContact O-CG 3.25Å; D546-Q550 PolarHBondContact O-N 3.22Å; L547-Q550 PolarHBondContact O-N 2.96Å
551K88.8Confident86.6Confident67 Ų6758.3 Ų58.329%0.29130%0.299SS..Hα-helixtrans-81.4-36.9179.7-166.6172.2-174.9-176.40114.1V515 D516 L547 L548 R549V515-K551 HydrophobicContact CG1-CB 4.11Å; V515-K551 HydrophobicContact CG1-CD 3.67Å; D516-K551 IonicContact OD1-NZ 3.6Å; D516-K551 PolarHBondContact OD1-NZ 3.27Å; L547-K551 PolarHBondContact O-N 2.85Å; L547-K551 VanDerWaalsContact O-N 3.15Å; L548-K551 PolarHBondContact O-N 2.89Å; R549-K551 PolarHBondContact O-N 3Å
552L89.1Confident86.6Confident1 Ų159.8 Ų59.81%0.00531%0.306CS..Hα-helixtrans-107.1-34-165.4-66.6164.8000114.8V518 I522 L548 R549 A554 R555 H556 M559 I561V518-L552 HydrophobicContact CG1-CD1 4.39Å; I522-L552 HydrophobicContact CD1-CD1 3.65Å; I522-L552 HydrophobicContact CD1-CD2 4.24Å; L548-L552 HydrophobicContact CB-CD1 4.45Å; L548-L552 HydrophobicContact CD2-CD1 4.04Å; L548-L552 VanDerWaalsContact O-CB 3.25Å; L548-L552 WeakPolarHBondContact O-CB 3.49Å; L548-L552 WeakPolarHBondContact O-CG 3.2Å; L548-L552 PolarHBondContact O-N 2.93Å; R549-L552 PolarHBondContact O-N 3.08Å; L552-A554 PolarHBondContact O-N 2.94Å; L552-A554 VanDerWaalsContact O-N 3.17Å; L552-R555 PolarHBondContact O-N 2.55Å; L552-H556 PolarHBondContact O-N 3.32Å; L552-M559 HydrophobicContact CB-CE 3.74Å; L552-M559 HydrophobicContact CD1-CE 3.92Å; L552-M559 HydrophobicContact CD2-CE 4.38Å; L552-M559 HydrophobicContact CG-CE 4.23Å; L552-I561 HydrophobicContact CB-CD1 3.69Å; L552-I561 HydrophobicContact CD1-CD1 4.16Å
553S82.7Confident86.8Confident50 Ų5056 Ų5635%0.3529%0.288SS..THydrogen-bonded Turntrans-63.6-26.7-172.6-63.10000113.4R549 R555 P557R549-S553 WeakPolarHBondContact CA-OG 3.31Å; R549-S553 VanDerWaalsContact O-CB 3.23Å; R549-S553 WeakPolarHBondContact O-CB 3.47Å; R549-S553 PolarHBondContact O-N 2.89Å; R549-S553 PolarHBondContact O-OG 2.98Å; S553-R555 VanDerWaalsContact C-N 3.32Å; S553-P557 WeakPolarHBondContact O-CA 3.38Å
554A81.2Confident86.8Confident97 Ų9754 Ų5480%0.80228%0.277SS*.THydrogen-bonded Turntrans-72.1-22.5174.300000113.8L552L552-A554 PolarHBondContact O-N 2.94Å; L552-A554 VanDerWaalsContact O-N 3.17Å
555R84.8Confident86.4Confident164 Ų16456.3 Ų56.362%0.61929%0.289SS*.THydrogen-bonded Turntrans-97.2-35.2177.9-65.7-179.2178.5176.8-0.5112.4L552 S553L552-R555 PolarHBondContact O-N 2.55Å; S553-R555 VanDerWaalsContact C-N 3.32Å
556H86.3Confident85.9Confident35 Ų3557.9 Ų57.916%0.16231%0.306CS..  trans-133.973.7-173.8-54.8-67000110.3A532 L552 E558 M559A532-H556 HydrophobicContact CB-CB 4.06Å; L552-H556 PolarHBondContact O-N 3.32Å; H556-E558 PolarHBondContact O-N 3.11Å; H556-M559 HydrophobicContact CB-CB 3.93Å; H556-M559 HydrophobicContact CB-CE 4.22Å; H556-M559 WeakPolarHBondContact O-CB 3.3Å; H556-M559 PolarHBondContact O-N 2.79Å; H556-M559 VanDerWaalsContact O-N 3.16Å
557P79Confident85.7Confident111 Ų11154.7 Ų54.772%0.72129%0.289SS*.THydrogen-bonded Turntrans-66.9-21.8-174.626.6-35.5000114S553S553-P557 WeakPolarHBondContact O-CA 3.38Å
558E83.9Confident85.2Confident131 Ų13155.1 Ų55.161%0.61229%0.291SS*.THydrogen-bonded Turntrans-82.4-11.1176.3-58.4-172161.500113.9K533 H556K533-E558 HydrophobicContact CB-CB 4.12Å; H556-E558 PolarHBondContact O-N 3.11Å
559M89.4Confident84.2Confident10 Ų1057.4 Ų57.45%0.04931%0.314CS..SBendtrans-80.2133.9-175.7-173.6173.767.100111.3I522 A532 I535 V537 L552 H556 I561I522-M559 HydrophobicContact CD1-CE 3.92Å; I522-M559 HydrophobicContact CD1-SD 4.01Å; I522-M559 HydrophobicContact CG1-SD 4.39Å; I522-M559 HydrophobicContact CG2-CE 4.25Å; I522-M559 HydrophobicContact CG2-SD 3.78Å; A532-M559 HydrophobicContact CB-CB 4.36Å; A532-M559 WeakPolarHBondContact O-CA 3.46Å; I535-M559 HydrophobicContact CB-CG 4.37Å; I535-M559 HydrophobicContact CB-SD 4.33Å; I535-M559 HydrophobicContact CG2-CG 4.45Å; I535-M559 HydrophobicContact CG2-SD 4.01Å; V537-M559 HydrophobicContact CG2-CE 3.88Å; V537-M559 HydrophobicContact CG2-SD 3.92Å; L552-M559 HydrophobicContact CB-CE 3.74Å; L552-M559 HydrophobicContact CD1-CE 3.92Å; L552-M559 HydrophobicContact CD2-CE 4.38Å; L552-M559 HydrophobicContact CG-CE 4.23Å; H556-M559 HydrophobicContact CB-CB 3.93Å; H556-M559 HydrophobicContact CB-CE 4.22Å; H556-M559 WeakPolarHBondContact O-CB 3.3Å; H556-M559 PolarHBondContact O-N 2.79Å; H556-M559 VanDerWaalsContact O-N 3.16Å; M559-I561 HydrophobicContact CE-CD1 3.81Å; M559-I561 HydrophobicContact CE-CG1 4Å; M559-I561 PolarHBondContact O-N 2.74Å
560E87.6Confident84.1Confident38 Ų3857.4 Ų57.418%0.17831%0.314CS..EExtended strand (participates in β ladder)trans-86.4116.6-179.4-67.3-169.1-124.500111.8A536 V537 K562 F567 R570 K572A536-E560 CarbonylContact C-O 3.18Å; A536-E560 VanDerWaalsContact CA-O 3.32Å; A536-E560 WeakPolarHBondContact CA-O 3.45Å; A536-E560 HydrophobicContact CB-CB 4.37Å; V537-E560 PolarHBondContact N-O 3.11Å; E560-K562 VanDerWaalsContact OE2-CE 3.28Å; E560-K562 WeakPolarHBondContact OE2-CE 3.43Å; E560-K562 IonicContact OE2-NZ 3.77Å; E560-K562 PolarHBondContact OE2-NZ 3.3Å; E560-F567 HydrophobicContact CB-CE2 3.79Å; E560-R570 IonicContact OE1-NH1 3.17Å; E560-R570 IonicContact OE2-CZ 2.69Å; E560-R570 IonicContact OE2-NE 3.23Å; E560-R570 IonicContact OE2-NH1 3.01Å; E560-R570 PolarHBondContact OE2-NH1 3.29Å; E560-K572 WeakPolarHBondContact OE1-CE 3.18Å; E560-K572 IonicContact OE1-NZ 3.25Å; E560-K572 PolarHBondContact OE1-NZ 3.1Å
561I90.3Very high84.4Confident9 Ų953.8 Ų53.85%0.04630%0.297CS..EExtended strand (participates in β ladder)trans-117.4111.4176.5-52.1173.7000109.1V537 V545 L548 R549 L552 M559V537-I561 HydrophobicContact CB-CG1 4.16Å; V537-I561 HydrophobicContact CB-CG2 4.27Å; V537-I561 HydrophobicContact CG2-CG1 4.17Å; V537-I561 WeakPolarHBondContact O-CA 3.2Å; V545-I561 HydrophobicContact CG1-CG2 4.25Å; L548-I561 HydrophobicContact CB-CG2 3.67Å; L548-I561 HydrophobicContact CD1-CG2 4.38Å; R549-I561 HydrophobicContact CG-CB 3.95Å; R549-I561 HydrophobicContact CG-CD1 4.29Å; R549-I561 HydrophobicContact CG-CG2 3.93Å; R549-I561 PolarHBondContact NE-O 2.96Å; R549-I561 VanDerWaalsContact NE-O 3.13Å; R549-I561 PolarHBondContact NH2-O 3.43Å; L552-I561 HydrophobicContact CB-CD1 3.69Å; L552-I561 HydrophobicContact CD1-CD1 4.16Å; M559-I561 HydrophobicContact CE-CD1 3.81Å; M559-I561 HydrophobicContact CE-CG1 4Å; M559-I561 PolarHBondContact O-N 2.74Å
562K87.8Confident84.7Confident45 Ų4552.2 Ų52.220%0.19629%0.291CS..EExtended strand (participates in β ladder)trans-148166.8-171.5-56.4-167.1-173.1-177.90113.8V537 I538 A539 V545 E560 G566 F567V537-K562 PolarHBondContact O-N 2.95Å; V537-K562 VanDerWaalsContact O-N 3.08Å; I538-K562 WeakPolarHBondContact CA-O 3.47Å; A539-K562 PolarHBondContact N-O 3.48Å; V545-K562 VanDerWaalsContact CG2-C 3.48Å; E560-K562 VanDerWaalsContact OE2-CE 3.28Å; E560-K562 WeakPolarHBondContact OE2-CE 3.43Å; E560-K562 IonicContact OE2-NZ 3.77Å; E560-K562 PolarHBondContact OE2-NZ 3.3Å; K562-G566 WeakPolarHBondContact CD-O 3.5Å; K562-F567 HydrophobicContact CB-CD2 4.17Å; K562-F567 HydrophobicContact CD-CD2 4.05Å; K562-F567 HydrophobicContact CG-CD2 4.29Å
563S88.4Confident85.1Confident24 Ų2453.4 Ų53.417%0.16830%0.296CS..  trans-69.3160.6161.259.70000111.2A539 D565 G566 F567A539-S563 VanDerWaalsContact O-CA 3.29Å; A539-S563 WeakPolarHBondContact O-CA 3.03Å; S563-D565 VanDerWaalsContact C-N 3.32Å; S563-D565 PolarHBondContact O-N 3.15Å; S563-G566 CarbonylContact O-C 3.48Å; S563-G566 PolarHBondContact O-N 3.08Å; S563-G566 VanDerWaalsContact O-N 3.12Å; S563-G566 PolarHBondContact OG-N 3.12Å; S563-F567 PolarHBondContact O-N 3.29Å
564V87.1Confident85.8Confident2 Ų251 Ų511%0.01228%0.279CS..SBendtrans-55.3-49.8177-175.90000110.9L404 I538 G566 F567 Q568 R596 V599 A600L404-V564 HydrophobicContact CD1-CG1 4.49Å; I538-V564 HydrophobicContact CG2-CB 4.26Å; I538-V564 HydrophobicContact CG2-CG2 3.56Å; V564-G566 VanDerWaalsContact C-N 3.26Å; V564-G566 PolarHBondContact O-N 3.36Å; V564-F567 WeakPolarHBondContact O-CA 3.34Å; V564-F567 WeakPolarHBondContact O-CB 3.25Å; V564-F567 PolarHBondContact O-N 3.06Å; V564-Q568 PolarHBondContact O-N 3.18Å; V564-R596 HydrophobicContact CB-CG 3.69Å; V564-R596 HydrophobicContact CG1-CG 3.67Å; V564-R596 WeakPolarHBondContact CG1-O 3.36Å; V564-R596 HydrophobicContact CG2-CG 3.8Å; V564-V599 HydrophobicContact CG1-CB 3.99Å; V564-V599 HydrophobicContact CG1-CG1 3.67Å; V564-A600 HydrophobicContact CG1-CB 4.03Å; V564-A600 HydrophobicContact CG2-CB 3.95Å
565D82.8Confident86.6Confident49 Ų4946.4 Ų46.426%0.26224%0.241SC..G310 helixtrans-57.6-38.5177.4-53.4-120.2000111.5L404 S563 F567 R596L404-D565 HydrophobicContact CD1-CB 4.07Å; S563-D565 VanDerWaalsContact C-N 3.32Å; S563-D565 PolarHBondContact O-N 3.15Å; D565-F567 PolarHBondContact O-N 3.25Å; D565-R596 IonicContact OD1-NH2 3.6Å; D565-R596 IonicContact OD2-NE 3.83Å; D565-R596 PolarHBondContact OD2-NE 2.98Å
566G76.8Confident87.3Confident36 Ų3638.6 Ų38.637%0.37121%0.212SC..G310 helixtrans-72.9-7.9174.400000115.4K562 S563 V564K562-G566 WeakPolarHBondContact CD-O 3.5Å; S563-G566 CarbonylContact O-C 3.48Å; S563-G566 PolarHBondContact O-N 3.08Å; S563-G566 VanDerWaalsContact O-N 3.12Å; S563-G566 PolarHBondContact OG-N 3.12Å; V564-G566 VanDerWaalsContact C-N 3.26Å; V564-G566 PolarHBondContact O-N 3.36Å
567F80.9Confident87.8Confident1 Ų137 Ų370%0.00420%0.204CC..G310 helixtrans-109.50.2179.9-141.7-88.9000113.8A536 I538 E560 K562 S563 V564 D565 R570 K572 R603A536-F567 HydrophobicContact CB-CD2 4.42Å; A536-F567 HydrophobicContact CB-CE1 4.2Å; A536-F567 HydrophobicContact CB-CE2 3.45Å; A536-F567 VanDerWaalsContact CB-CE2 3.45Å; A536-F567 HydrophobicContact CB-CZ 3.32Å; I538-F567 HydrophobicContact CD1-CB 4.18Å; I538-F567 HydrophobicContact CD1-CD1 3.9Å; I538-F567 HydrophobicContact CD1-CD2 4.43Å; I538-F567 HydrophobicContact CD1-CE1 4.47Å; I538-F567 HydrophobicContact CD1-CG 3.89Å; I538-F567 HydrophobicContact CG1-CD2 4.41Å; I538-F567 HydrophobicContact CG1-CG 4.31Å; E560-F567 HydrophobicContact CB-CE2 3.79Å; K562-F567 HydrophobicContact CB-CD2 4.17Å; K562-F567 HydrophobicContact CD-CD2 4.05Å; K562-F567 HydrophobicContact CG-CD2 4.29Å; S563-F567 PolarHBondContact O-N 3.29Å; V564-F567 WeakPolarHBondContact O-CA 3.34Å; V564-F567 WeakPolarHBondContact O-CB 3.25Å; V564-F567 PolarHBondContact O-N 3.06Å; D565-F567 PolarHBondContact O-N 3.25Å; F567-R570 HydrophobicContact CD1-CB 3.66Å; F567-R570 HydrophobicContact CE1-CB 3.49Å; F567-R570 VanDerWaalsContact CE1-CB 3.49Å; F567-R570 HydrophobicContact CG-CB 4.33Å; F567-R570 HydrophobicContact CZ-CB 4.01Å; F567-R570 WeakPolarHBondContact O-CB 3.42Å; F567-R570 PolarHBondContact O-N 2.98Å; F567-R570 VanDerWaalsContact O-N 3.14Å; F567-K572 HydrophobicContact CE1-CG 4.3Å; F567-K572 HydrophobicContact CZ-CG 3.77Å; F567-R603 HydrophobicContact CD1-CB 4.03Å; F567-R603 HydrophobicContact CD1-CG 3.65Å; F567-R603 HydrophobicContact CE1-CB 4.17Å; F567-R603 HydrophobicContact CE1-CG 4.3Å
568Q77.1Confident88.7Confident33 Ų3331.7 Ų31.715%0.15417%0.17CC..THydrogen-bonded Turntrans-57.6143176.7-170.5166.51.200111.6V564 R570V564-Q568 PolarHBondContact O-N 3.18Å; Q568-R570 PolarHBondContact O-N 3.14Å
569G71.1Confident89.2Confident48 Ų4825.5 Ų25.550%0.49514%0.141SC..THydrogen-bonded Turntrans72.9-3.8-175.400000115.8
570R84.8Confident89.4Confident99 Ų9925 Ų2537%0.37414%0.139SC..  trans-100.1171.3176.3-56.3-179.9-177.3-117.2-22.3111.9E560 F567 Q568 R603E560-R570 IonicContact OE1-NH1 3.17Å; E560-R570 IonicContact OE2-CZ 2.69Å; E560-R570 IonicContact OE2-NE 3.23Å; E560-R570 IonicContact OE2-NH1 3.01Å; E560-R570 PolarHBondContact OE2-NH1 3.29Å; F567-R570 HydrophobicContact CD1-CB 3.66Å; F567-R570 HydrophobicContact CE1-CB 3.49Å; F567-R570 VanDerWaalsContact CE1-CB 3.49Å; F567-R570 HydrophobicContact CG-CB 4.33Å; F567-R570 HydrophobicContact CZ-CB 4.01Å; F567-R570 WeakPolarHBondContact O-CB 3.42Å; F567-R570 PolarHBondContact O-N 2.98Å; F567-R570 VanDerWaalsContact O-N 3.14Å; Q568-R570 PolarHBondContact O-N 3.14Å; R570-R603 WeakPolarHBondContact O-CD 3.23Å; R570-R603 PolarHBondContact O-NH1 2.69Å
571E91.9Very high89.7Confident80 Ų8023.8 Ų23.837%0.37413%0.132SC..  trans-154.9158.7173.657.6-175.7-122.600110.3R443 R603 R605R443-E571 IonicContact CZ-OE2 3.65Å; R443-E571 IonicContact NE-OE2 3.89Å; R443-E571 PolarHBondContact NE-OE2 3.48Å; R443-E571 IonicContact NH2-OE2 2.74Å; R443-E571 PolarHBondContact NH2-OE2 3.2Å; E571-R603 VanDerWaalsContact CA-O 3.29Å; E571-R603 WeakPolarHBondContact CA-O 3.39Å; E571-R605 IonicContact OE1-NE 3.2Å
572K95.9Very high89.8Confident34 Ų3423.9 Ų23.915%0.14813%0.134CC..EExtended strand (participates in β ladder)trans-146.5160176.1-71.9-63.2-177.9-1770111.5K533 A536 E560 F567 A574 V575 R603 A604 R605K533-K572 WeakPolarHBondContact O-CD 3.22Å; K533-K572 WeakPolarHBondContact O-CE 3.23Å; K533-K572 PolarHBondContact O-NZ 2.96Å; A536-K572 HydrophobicContact CB-CB 4.32Å; A536-K572 HydrophobicContact CB-CG 3.62Å; E560-K572 WeakPolarHBondContact OE1-CE 3.18Å; E560-K572 IonicContact OE1-NZ 3.25Å; E560-K572 PolarHBondContact OE1-NZ 3.1Å; F567-K572 HydrophobicContact CE1-CG 4.3Å; F567-K572 HydrophobicContact CZ-CG 3.77Å; K572-A574 WeakPolarHBondContact CB-O 3.4Å; K572-V575 HydrophobicContact CB-CG2 4.25Å; K572-R603 PolarHBondContact N-O 3.41Å; K572-A604 CarbonylContact O-C 3.57Å; K572-R605 WeakPolarHBondContact O-CB 3.21Å; K572-R605 WeakPolarHBondContact O-CG 3.45Å; K572-R605 PolarHBondContact O-N 2.83Å
573E97.4Very high90Very high26 Ų2623 Ų2312%0.12113%0.131CC..EExtended strand (participates in β ladder)trans-64.4-45.7176.1-59-65.3-179.900111L472 L475 D534 R605 R606 H607L472-E573 HydrophobicContact CD2-CB 4.09Å; L475-E573 HydrophobicContact CD1-CB 3.96Å; L475-E573 HydrophobicContact CD1-CG 4.02Å; L475-E573 HydrophobicContact CD2-CG 4.34Å; D534-E573 HydrophobicContact CB-CB 4.26Å; D534-E573 HydrophobicContact CB-CG 4.07Å; D534-E573 PolarHBondContact O-N 3.3Å; D534-E573 VanDerWaalsContact O-N 3.09Å; E573-R605 IonicContact OE1-CZ 3.51Å; E573-R605 IonicContact OE1-NH1 3.82Å; E573-R605 PolarHBondContact OE1-NH1 3.1Å; E573-R605 IonicContact OE1-NH2 2.72Å; E573-R605 IonicContact OE2-CZ 2.69Å; E573-R605 IonicContact OE2-NE 3.5Å; E573-R605 IonicContact OE2-NH1 3.62Å; E573-R606 PolarHBondContact O-N 3.45Å; E573-R606 WeakPolarHBondContact OE2-CD 3.46Å; E573-R606 IonicContact OE2-NE 3.12Å; E573-R606 PolarHBondContact OE2-NE 3.18Å; E573-H607 PolarHBondContact O-N 3.32Å
574A97.9Very high89.9Confident0 Ų034.4 Ų34.40%017%0.17CC..EExtended strand (participates in β ladder)trans-118.9139.517300000112L472 L525 D534 I535 A536 K572 H607L472-A574 HydrophobicContact CD1-CB 4.12Å; L472-A574 HydrophobicContact CD2-CB 4.07Å; L525-A574 HydrophobicContact CD1-CB 4.31Å; D534-A574 PolarHBondContact O-N 3.38Å; D534-A574 VanDerWaalsContact O-N 3.14Å; I535-A574 WeakPolarHBondContact CA-O 3.44Å; I535-A574 HydrophobicContact CG1-CB 4.26Å; A536-A574 PolarHBondContact N-O 3.44Å; K572-A574 WeakPolarHBondContact CB-O 3.4Å; A574-H607 WeakPolarHBondContact CA-O 3.44Å
575V98.1Very high89.9Confident0 Ų041.7 Ų41.70%020%0.202CC..EExtended strand (participates in β ladder)trans-125.8134.9171.1173.70000110A536 I538 K572 R603 A604 H607 I608 A609A536-V575 CarbonylContact O-C 3.58Å; A536-V575 WeakPolarHBondContact O-CA 3.3Å; I538-V575 HydrophobicContact CD1-CG1 3.74Å; I538-V575 HydrophobicContact CG1-CG1 4.07Å; K572-V575 HydrophobicContact CB-CG2 4.25Å; V575-R603 HydrophobicContact CG2-CB 4Å; V575-A604 HydrophobicContact CB-CB 4.07Å; V575-A604 HydrophobicContact CG2-CB 4.02Å; V575-H607 PolarHBondContact N-O 2.89Å; V575-I608 WeakPolarHBondContact O-CA 3.42Å; V575-A609 PolarHBondContact O-N 3.05Å
576V98.1Very high90.1Very high0 Ų040.1 Ų40.10%020%0.198CC..EExtended strand (participates in β ladder)trans-114.7117.5171.5-170.50000108.7V518 I522 A536 V537 I538 A609 V611V518-V576 HydrophobicContact CB-CG1 4.4Å; V518-V576 HydrophobicContact CG1-CG1 3.97Å; V518-V576 HydrophobicContact CG2-CG1 3.93Å; I522-V576 HydrophobicContact CG1-CG2 4.26Å; A536-V576 PolarHBondContact O-N 3.07Å; V537-V576 CarbonylContact C-O 3.56Å; V537-V576 WeakPolarHBondContact CA-O 3.23Å; I538-V576 PolarHBondContact N-O 3.3Å; V576-A609 CarbonylContact C-O 3.49Å; V576-A609 WeakPolarHBondContact CA-O 3.45Å; V576-A609 HydrophobicContact CG1-CB 4.27Å; V576-A609 HydrophobicContact CG2-CB 4.43Å; V576-V611 HydrophobicContact CG1-CG2 4.36Å
577L97.8Very high90.6Very high1 Ų142.8 Ų42.81%0.00520%0.2CC..EExtended strand (participates in β ladder)trans-105.5122.5-177.4178.257.7000110.2I538 L579 A600 A609 V610 V611I538-L577 HydrophobicContact CB-CD1 4.21Å; I538-L577 HydrophobicContact CG2-CD1 4.06Å; I538-L577 WeakPolarHBondContact O-CA 3.42Å; I538-L577 WeakPolarHBondContact O-CD1 3.43Å; L577-L579 HydrophobicContact CD1-CD2 4.11Å; L577-L579 HydrophobicContact CD2-CD2 3.84Å; L577-L579 HydrophobicContact CG-CD2 3.75Å; L577-A600 HydrophobicContact CD1-CB 4.07Å; L577-A600 HydrophobicContact CD2-CB 4.04Å; L577-A609 PolarHBondContact N-O 2.95Å; L577-V610 HydrophobicContact CB-CG2 4.33Å; L577-V610 HydrophobicContact CD2-CG2 4.29Å; L577-V610 WeakPolarHBondContact O-CA 3.42Å; L577-V611 PolarHBondContact O-N 3.12Å
578S97.2Very high90.7Very high0 Ų043.4 Ų43.40%020%0.204CC..EExtended strand (participates in β ladder)trans-105.7118.3173164.50000109.1E514 I538 P540 Q544E514-S578 WeakPolarHBondContact OE2-CB 3.49Å; E514-S578 PolarHBondContact OE2-OG 2.77Å; I538-S578 PolarHBondContact O-N 3.46Å; P540-S578 WeakPolarHBondContact CD-O 3.45Å; Q544-S578 PolarHBondContact NE2-OG 2.69Å
579L95.3Very high91Very high1 Ų143.9 Ų43.91%0.00522%0.218CC..  trans-85.6-16.9-177.1-62.6-169.8000113.7E514 L577 R581 L591 I597 V610 V611 C612 V617 L623E514-L579 PolarHBondContact OE2-N 3.25Å; L577-L579 HydrophobicContact CD1-CD2 4.11Å; L577-L579 HydrophobicContact CD2-CD2 3.84Å; L577-L579 HydrophobicContact CG-CD2 3.75Å; L579-R581 PolarHBondContact O-N 2.98Å; L579-L591 HydrophobicContact CB-CD1 4.18Å; L579-L591 HydrophobicContact CB-CD2 4.4Å; L579-L591 HydrophobicContact CD2-CD2 3.97Å; L579-I597 HydrophobicContact CD2-CD1 4.43Å; L579-V610 HydrophobicContact CD1-CG1 4.1Å; L579-V610 HydrophobicContact CG-CG1 4.16Å; L579-V611 PolarHBondContact N-O 3.41Å; L579-C612 HydrophobicContact CB-CB 3.77Å; L579-C612 HydrophobicContact CD1-CB 3.63Å; L579-C612 HydrophobicContact CG-CB 3.84Å; L579-V617 HydrophobicContact CD1-CG1 3.93Å; L579-V617 HydrophobicContact CD1-CG2 4.08Å; L579-L623 HydrophobicContact CD1-CD2 4.44Å
580V94Very high91.3Very high0 Ų045.8 Ų45.80%021%0.213CC..  trans70.8-38.3171-165.40000115.8K509 N511 E514 Y541 Q544 S582K509-V580 HydrophobicContact CB-CG1 3.96Å; N511-V580 HydrophobicContact CB-CG1 3.97Å; N511-V580 PolarHBondContact ND2-O 2.94Å; E514-V580 VanDerWaalsContact CD-N 3.32Å; E514-V580 WeakPolarHBondContact OE1-CA 3.38Å; E514-V580 PolarHBondContact OE1-N 3.13Å; E514-V580 WeakPolarHBondContact OE2-CA 3.39Å; E514-V580 PolarHBondContact OE2-N 2.71Å; Y541-V580 HydrophobicContact CD2-CB 3.8Å; Y541-V580 HydrophobicContact CD2-CG1 4.22Å; Y541-V580 HydrophobicContact CD2-CG2 3.87Å; Y541-V580 HydrophobicContact CE2-CB 4.28Å; Q544-V580 HydrophobicContact CB-CG1 4.44Å; Q544-V580 HydrophobicContact CB-CG2 3.64Å; Q544-V580 HydrophobicContact CG-CG2 3.49Å; Q544-V580 VanDerWaalsContact CG-CG2 3.49Å; V580-S582 PolarHBondContact O-N 3.44Å
581R93.2Very high91.1Very high12 Ų1241.1 Ų41.15%0.04520%0.195CC..  trans-76.2110.2-171.9-59.9-54.1-58.1-85.76.2111.1E500 Y541 L579 N583 E587 V588 L591 T616E500-R581 IonicContact OE1-CZ 2.68Å; E500-R581 IonicContact OE1-NE 2.65Å; E500-R581 PolarHBondContact OE1-NE 2.96Å; E500-R581 IonicContact OE1-NH2 3.37Å; E500-R581 PolarHBondContact OE1-NH2 3.24Å; E500-R581 IonicContact OE2-CZ 2.72Å; E500-R581 IonicContact OE2-NE 3.89Å; E500-R581 PolarHBondContact OE2-NE 3.39Å; E500-R581 IonicContact OE2-NH2 2.62Å; E500-R581 PolarHBondContact OE2-NH2 3.07Å; Y541-R581 HydrophobicContact CE2-CG 3.94Å; Y541-R581 WeakPolarHBondContact OH-CD 3.36Å; L579-R581 PolarHBondContact O-N 2.98Å; R581-N583 PolarHBondContact NH2-ND2 2.72Å; R581-E587 PolarHBondContact NH1-O 3.46Å; R581-E587 PolarHBondContact NH2-O 3.33Å; R581-E587 VanDerWaalsContact NH2-O 3.08Å; R581-V588 WeakPolarHBondContact CG-O 3.43Å; R581-V588 PolarHBondContact NH1-O 3.42Å; R581-L591 HydrophobicContact CB-CD1 3.82Å; R581-L591 HydrophobicContact CG-CD1 3.49Å; R581-L591 VanDerWaalsContact CG-CD1 3.49Å; R581-L591 HydrophobicContact CG-CG 4.11Å; R581-T616 HydrophobicContact CB-CG2 4.13Å; R581-T616 WeakPolarHBondContact O-CB 3.08Å; R581-T616 WeakPolarHBondContact O-CG2 3.31Å
582S93.1Very high90.7Very high10 Ų1039.4 Ų39.47%0.0720%0.195CC..  trans-138.5106.9168.5178.40000108.7L498 E500 V580 D613 T616L498-S582 WeakPolarHBondContact O-CB 3.42Å; E500-S582 WeakPolarHBondContact CG-O 3.37Å; E500-S582 PolarHBondContact N-O 3Å; V580-S582 PolarHBondContact O-N 3.44Å; S582-D613 VanDerWaalsContact CA-OD2 3.31Å; S582-D613 WeakPolarHBondContact CA-OD2 3.46Å; S582-D613 VanDerWaalsContact CB-OD2 3.26Å; S582-D613 WeakPolarHBondContact CB-OD2 3.21Å; S582-D613 PolarHBondContact OG-OD2 3.06Å; S582-T616 WeakPolarHBondContact CA-OG1 3.46Å
583N90.9Very high90.4Very high28 Ų2840.8 Ų40.815%0.1520%0.202CC..  trans-152.6150.1-177.562.577.4000112.7E500 R581 K585 G586 E587 T616E500-N583 HydrophobicContact CG-CB 4.37Å; E500-N583 PolarHBondContact OE2-ND2 3.08Å; R581-N583 PolarHBondContact NH2-ND2 2.72Å; N583-K585 PolarHBondContact O-N 3.48Å; N583-K585 PolarHBondContact OD1-N 2.97Å; N583-G586 PolarHBondContact O-N 2.9Å; N583-G586 VanDerWaalsContact O-N 3.17Å; N583-G586 PolarHBondContact OD1-N 2.93Å; N583-G586 VanDerWaalsContact OD1-N 3.13Å; N583-E587 PolarHBondContact ND2-O 2.63Å; N583-E587 PolarHBondContact OD1-N 3.44Å; N583-T616 PolarHBondContact N-OG1 2.69Å; N583-T616 PolarHBondContact O-OG1 3.34Å
584R87.2Confident90.2Very high262 Ų26242 Ų4299%0.98921%0.209SC*.THydrogen-bonded Turntrans-65.7-7.1-176.8-63.1-176.9-178.8179.90.2115.2
585K86.9Confident90Very high156 Ų15645.1 Ų45.168%0.67822%0.221SC*.THydrogen-bonded Turntrans-94.7-13.5179.4-58.4-176.8-178.4174.90113.1N583 E587N583-K585 PolarHBondContact O-N 3.48Å; N583-K585 PolarHBondContact OD1-N 2.97Å; K585-E587 VanDerWaalsContact C-N 3.28Å; K585-E587 HydrophobicContact CB-CG 3.91Å; K585-E587 VanDerWaalsContact CD-CD 3.42Å; K585-E587 HydrophobicContact CD-CG 4.16Å; K585-E587 WeakPolarHBondContact CD-OE1 3.39Å; K585-E587 IonicContact NZ-OE1 3.87Å; K585-E587 PolarHBondContact NZ-OE1 3.09Å; K585-E587 IonicContact NZ-OE2 3.16Å
586G86.1Confident89.7Confident16 Ų1645.7 Ų45.717%0.16522%0.223CC..  trans72.417.4-172.300000114.2N583 V588 N619N583-G586 PolarHBondContact O-N 2.9Å; N583-G586 VanDerWaalsContact O-N 3.17Å; N583-G586 PolarHBondContact OD1-N 2.93Å; N583-G586 VanDerWaalsContact OD1-N 3.13Å; G586-V588 PolarHBondContact O-N 3.14Å; G586-N619 VanDerWaalsContact CA-ND2 3.3Å; G586-N619 WeakPolarHBondContact CA-ND2 3.41Å
587E87.4Confident89.5Confident92 Ų9245.8 Ų45.843%0.4322%0.223SC..  trans-79.2118.5-177.3-73.8173.9-170.900111.1R581 N583 K585R581-E587 PolarHBondContact NH1-O 3.46Å; R581-E587 PolarHBondContact NH2-O 3.33Å; R581-E587 VanDerWaalsContact NH2-O 3.08Å; N583-E587 PolarHBondContact ND2-O 2.63Å; N583-E587 PolarHBondContact OD1-N 3.44Å; K585-E587 VanDerWaalsContact C-N 3.28Å; K585-E587 HydrophobicContact CB-CG 3.91Å; K585-E587 VanDerWaalsContact CD-CD 3.42Å; K585-E587 HydrophobicContact CD-CG 4.16Å; K585-E587 WeakPolarHBondContact CD-OE1 3.39Å; K585-E587 IonicContact NZ-OE1 3.87Å; K585-E587 PolarHBondContact NZ-OE1 3.09Å; K585-E587 IonicContact NZ-OE2 3.16Å
588V84.2Confident89.4Confident13 Ų1345.7 Ų45.78%0.07922%0.223CC..  trans-93.1-25175.9-54.90000113.4Y541 R581 G586 F590 L591 A592 T616 H620 L623Y541-V588 PolarHBondContact OH-O 3.45Å; R581-V588 WeakPolarHBondContact CG-O 3.43Å; R581-V588 PolarHBondContact NH1-O 3.42Å; G586-V588 PolarHBondContact O-N 3.14Å; V588-F590 PolarHBondContact O-N 3.19Å; V588-L591 HydrophobicContact CB-CB 3.99Å; V588-L591 HydrophobicContact CB-CD1 4.23Å; V588-L591 HydrophobicContact CG2-CB 4.37Å; V588-L591 PolarHBondContact O-N 2.82Å; V588-A592 HydrophobicContact CG2-CB 4.04Å; V588-T616 WeakPolarHBondContact CG1-O 3.37Å; V588-H620 HydrophobicContact CG1-CB 4.3Å; V588-H620 HydrophobicContact CG2-CB 3.91Å; V588-L623 HydrophobicContact CB-CD1 4.26Å; V588-L623 HydrophobicContact CG1-CD1 4.19Å; V588-L623 HydrophobicContact CG2-CD1 4.43Å
589G83.2Confident89.3Confident44 Ų4445.7 Ų45.745%0.45422%0.223SC..G310 helixtrans56.2-126.2177.400000113.3L591 A592G589-L591 PolarHBondContact O-N 2.91Å; G589-A592 VanDerWaalsContact O-CB 3.24Å; G589-A592 WeakPolarHBondContact O-CB 3.24Å; G589-A592 PolarHBondContact O-N 3.4Å
590F75.8Confident89.3Confident88 Ų8845.7 Ų45.739%0.38622%0.223SC..G310 helixtrans-56-14-179-172.4-110.1000115.8P540 Y541 V588 A592 R596P540-F590 HydrophobicContact CB-CD1 4.19Å; P540-F590 HydrophobicContact CB-CE1 4.43Å; P540-F590 WeakPolarHBondContact O-CE1 3.34Å; Y541-F590 HydrophobicContact CE1-CB 3.98Å; Y541-F590 HydrophobicContact CE1-CD1 4.44Å; V588-F590 PolarHBondContact O-N 3.19Å; F590-A592 VanDerWaalsContact C-N 3.29Å; F590-R596 VanDerWaalsContact CE1-CZ 3.5Å; F590-R596 VanDerWaalsContact CZ-NH1 3.32Å; F590-R596 PolarHBondContact O-NH1 2.91Å
591L81.1Confident89.4Confident1 Ų145.8 Ų45.81%0.00522%0.224CC..G310 helixtrans-70.9-18.1169.1-73.3178.2000114.2P540 Y541 L579 R581 V588 G589 E593 I597 L623P540-L591 HydrophobicContact CB-CD2 4.13Å; P540-L591 HydrophobicContact CG-CD2 3.32Å; P540-L591 HydrophobicContact CG-CG 4.43Å; Y541-L591 HydrophobicContact CE2-CG 4.45Å; L579-L591 HydrophobicContact CB-CD1 4.18Å; L579-L591 HydrophobicContact CB-CD2 4.4Å; L579-L591 HydrophobicContact CD2-CD2 3.97Å; R581-L591 HydrophobicContact CB-CD1 3.82Å; R581-L591 HydrophobicContact CG-CD1 3.49Å; R581-L591 VanDerWaalsContact CG-CD1 3.49Å; R581-L591 HydrophobicContact CG-CG 4.11Å; V588-L591 HydrophobicContact CB-CB 3.99Å; V588-L591 HydrophobicContact CB-CD1 4.23Å; V588-L591 HydrophobicContact CG2-CB 4.37Å; V588-L591 PolarHBondContact O-N 2.82Å; G589-L591 PolarHBondContact O-N 2.91Å; L591-E593 PolarHBondContact O-N 2.86Å; L591-E593 VanDerWaalsContact O-N 3.13Å; L591-I597 HydrophobicContact CD2-CD1 3.89Å; L591-L623 HydrophobicContact CB-CD1 3.91Å; L591-L623 HydrophobicContact CD1-CD1 4.32Å
592A84.2Confident89.5Confident43 Ų4345.2 Ų45.236%0.35522%0.222SC..G310 helixtrans-71.52.5-178.700000114.1V588 G589 F590 D594V588-A592 HydrophobicContact CG2-CB 4.04Å; G589-A592 VanDerWaalsContact O-CB 3.24Å; G589-A592 WeakPolarHBondContact O-CB 3.24Å; G589-A592 PolarHBondContact O-N 3.4Å; F590-A592 VanDerWaalsContact C-N 3.29Å; A592-D594 PolarHBondContact O-N 2.99Å
593E88.9Confident89.6Confident63 Ų6345 Ų4529%0.29422%0.219SC..  trans-92.692.6174.7-168.5-177154.500110L591 R595 R596L591-E593 PolarHBondContact O-N 2.86Å; L591-E593 VanDerWaalsContact O-N 3.13Å; E593-R595 PolarHBondContact O-N 3.28Å; E593-R595 VanDerWaalsContact O-N 3.1Å; E593-R596 HydrophobicContact CB-CB 4.47Å; E593-R596 VanDerWaalsContact O-CB 3.28Å; E593-R596 WeakPolarHBondContact O-CB 3.45Å; E593-R596 PolarHBondContact O-N 3.19Å; E593-R596 IonicContact OE1-NH2 2.68Å; E593-R596 IonicContact OE2-CZ 3.61Å; E593-R596 IonicContact OE2-NH1 3.66Å; E593-R596 PolarHBondContact OE2-NH1 2.7Å; E593-R596 IonicContact OE2-NH2 2.67Å; E593-R596 PolarHBondContact OE2-NH2 3.39Å
594D94.3Very high90Very high53 Ų5343.6 Ų43.628%0.28321%0.212SC..Hα-helixtrans-52.8-37.1-172.7-55.8-26.2000113.8M456 A592 R596 I597 N598 H620 F622M456-D594 VanDerWaalsContact CE-C 3.49Å; M456-D594 HydrophobicContact CE-CB 3.32Å; A592-D594 PolarHBondContact O-N 2.99Å; D594-R596 PolarHBondContact O-N 2.95Å; D594-I597 PolarHBondContact O-N 3.21Å; D594-I597 VanDerWaalsContact O-N 3.08Å; D594-N598 WeakPolarHBondContact O-CB 3.16Å; D594-N598 PolarHBondContact O-N 3.27Å; D594-H620 IonicContact OD1-CE1 3.77Å; D594-H620 PolarHBondContact OD1-CE1 3.3Å; D594-H620 IonicContact OD1-ND1 2.73Å; D594-F622 HydrophobicContact CB-CB 4.39Å; D594-F622 HydrophobicContact CB-CD1 3.65Å; D594-F622 HydrophobicContact CB-CD2 3.94Å; D594-F622 HydrophobicContact CB-CE1 3.83Å; D594-F622 HydrophobicContact CB-CE2 4.08Å; D594-F622 HydrophobicContact CB-CG 3.72Å; D594-F622 HydrophobicContact CB-CZ 4.05Å; D594-F622 WeakPolarHBondContact OD1-CB 3.13Å; D594-F622 WeakPolarHBondContact OD1-CD1 3.23Å; D594-F622 VanDerWaalsContact OD1-CG 3.27Å; D594-F622 WeakPolarHBondContact OD1-CG 3.47Å
595R93.3Very high90.5Very high64 Ų6434 Ų3424%0.24218%0.176CC..Hα-helixtrans-59-33.8177.6-57.7-167.6-165.9-1792.9112.1Y401 K402 Q403 E424 E593 V599Y401-R595 PolarHBondContact O-NE 3.34Å; Y401-R595 PolarHBondContact O-NH1 3.13Å; K402-R595 WeakPolarHBondContact O-CG 3.31Å; Q403-R595 WeakPolarHBondContact O-CD 3.47Å; E424-R595 IonicContact OE1-CZ 3.44Å; E424-R595 IonicContact OE1-NH1 3.59Å; E424-R595 PolarHBondContact OE1-NH1 3.05Å; E424-R595 IonicContact OE1-NH2 2.7Å; E424-R595 PolarHBondContact OE1-NH2 3.42Å; E424-R595 IonicContact OE2-CZ 3.95Å; E424-R595 IonicContact OE2-NH1 2.68Å; E424-R595 PolarHBondContact OE2-NH1 2.88Å; E424-R595 IonicContact OE2-NH2 2.72Å; E593-R595 PolarHBondContact O-N 3.28Å; E593-R595 VanDerWaalsContact O-N 3.1Å; R595-V599 VanDerWaalsContact O-CG2 3.3Å; R595-V599 WeakPolarHBondContact O-CG2 3.26Å; R595-V599 PolarHBondContact O-N 3.46Å
596R91.6Very high91Very high12 Ų1228.1 Ų28.15%0.04515%0.149CC..Hα-helixtrans-68.8-42.8175.6-172.4173.7-70.194.518.8110.8L404 V564 D565 F590 E593 D594 V599 A600L404-R596 HydrophobicContact CD2-CB 3.88Å; L404-R596 HydrophobicContact CD2-CG 4.21Å; V564-R596 HydrophobicContact CB-CG 3.69Å; V564-R596 HydrophobicContact CG1-CG 3.67Å; V564-R596 WeakPolarHBondContact CG1-O 3.36Å; V564-R596 HydrophobicContact CG2-CG 3.8Å; D565-R596 IonicContact OD1-NH2 3.6Å; D565-R596 IonicContact OD2-NE 3.83Å; D565-R596 PolarHBondContact OD2-NE 2.98Å; F590-R596 VanDerWaalsContact CE1-CZ 3.5Å; F590-R596 VanDerWaalsContact CZ-NH1 3.32Å; F590-R596 PolarHBondContact O-NH1 2.91Å; E593-R596 HydrophobicContact CB-CB 4.47Å; E593-R596 VanDerWaalsContact O-CB 3.28Å; E593-R596 WeakPolarHBondContact O-CB 3.45Å; E593-R596 PolarHBondContact O-N 3.19Å; E593-R596 IonicContact OE1-NH2 2.68Å; E593-R596 IonicContact OE2-CZ 3.61Å; E593-R596 IonicContact OE2-NH1 3.66Å; E593-R596 PolarHBondContact OE2-NH1 2.7Å; E593-R596 IonicContact OE2-NH2 2.67Å; E593-R596 PolarHBondContact OE2-NH2 3.39Å; D594-R596 PolarHBondContact O-N 2.95Å; R596-V599 PolarHBondContact O-N 3.02Å; R596-A600 WeakPolarHBondContact O-CB 3.4Å; R596-A600 PolarHBondContact O-N 3.4Å
597I94.1Very high91.6Very high2 Ų227.4 Ų27.41%0.0114%0.141CC..Hα-helixtrans-69-43.7179.3-53.2-60.7000110.9W451 L579 L591 D594 V599 A600 V601 F622 L623 L626W451-I597 HydrophobicContact CH2-CG2 4.03Å; W451-I597 HydrophobicContact CZ2-CG2 4.46Å; L579-I597 HydrophobicContact CD2-CD1 4.43Å; L591-I597 HydrophobicContact CD2-CD1 3.89Å; D594-I597 PolarHBondContact O-N 3.21Å; D594-I597 VanDerWaalsContact O-N 3.08Å; I597-V599 VanDerWaalsContact C-N 3.34Å; I597-V599 PolarHBondContact O-N 2.96Å; I597-A600 PolarHBondContact O-N 2.89Å; I597-A600 VanDerWaalsContact O-N 3.13Å; I597-V601 HydrophobicContact CG2-CG2 4.41Å; I597-V601 WeakPolarHBondContact O-CG2 3.44Å; I597-V601 PolarHBondContact O-N 2.96Å; I597-F622 HydrophobicContact CB-CD1 4.33Å; I597-F622 HydrophobicContact CB-CE1 3.9Å; I597-F622 HydrophobicContact CG2-CD1 4.47Å; I597-F622 HydrophobicContact CG2-CE1 4.03Å; I597-L623 HydrophobicContact CB-CD2 4.47Å; I597-L623 HydrophobicContact CD1-CD2 3.92Å; I597-L623 HydrophobicContact CG1-CD2 3.77Å; I597-L623 HydrophobicContact CG2-CD2 4Å; I597-L626 HydrophobicContact CG2-CD2 3.91Å
598N95.6Very high92.1Very high0 Ų023.1 Ų23.10%012%0.121CC..Hα-helixtrans-52.9-49.117017428000111.5K402 M456 Y457 D594 A600 T602K402-N598 PolarHBondContact O-ND2 3.33Å; M456-N598 HydrophobicContact CE-CB 4.03Å; M456-N598 HydrophobicContact CG-CB 3.93Å; M456-N598 HydrophobicContact SD-CB 4.22Å; Y457-N598 PolarHBondContact OH-ND2 2.9Å; D594-N598 WeakPolarHBondContact O-CB 3.16Å; D594-N598 PolarHBondContact O-N 3.27Å; N598-A600 PolarHBondContact O-N 3.15Å; N598-T602 WeakPolarHBondContact O-CB 3.5Å; N598-T602 WeakPolarHBondContact O-CG2 3.4Å; N598-T602 PolarHBondContact O-N 3.29Å; N598-T602 PolarHBondContact O-OG1 2.99Å
599V94.9Very high92.8Very high0 Ų022.5 Ų22.50%012%0.118CC..Hα-helixtrans-58.6-49.7174.8169.40000111.1Q403 L404 V564 R595 R596 I597 V601 T602 R603Q403-V599 HydrophobicContact CB-CG2 3.53Å; Q403-V599 HydrophobicContact CG-CG2 3.54Å; L404-V599 HydrophobicContact CD1-CG1 4.45Å; L404-V599 HydrophobicContact CG-CB 4.49Å; L404-V599 HydrophobicContact CG-CG2 4.09Å; V564-V599 HydrophobicContact CG1-CB 3.99Å; V564-V599 HydrophobicContact CG1-CG1 3.67Å; R595-V599 VanDerWaalsContact O-CG2 3.3Å; R595-V599 WeakPolarHBondContact O-CG2 3.26Å; R595-V599 PolarHBondContact O-N 3.46Å; R596-V599 PolarHBondContact O-N 3.02Å; I597-V599 VanDerWaalsContact C-N 3.34Å; I597-V599 PolarHBondContact O-N 2.96Å; V599-V601 PolarHBondContact O-N 3.26Å; V599-T602 PolarHBondContact O-N 3.35Å; V599-T602 PolarHBondContact O-OG1 3.13Å; V599-R603 WeakPolarHBondContact O-CD 3.37Å; V599-R603 VanDerWaalsContact O-CG 3.23Å; V599-R603 WeakPolarHBondContact O-CG 3.49Å; V599-R603 PolarHBondContact O-N 2.95Å; V599-R603 PolarHBondContact O-NE 3.48Å
600A94.8Very high93.5Very high0 Ų020.5 Ų20.50%010%0.097CC..Hα-helixtrans-58.4-47.6-177.300000113.1I538 V564 L577 R596 I597 N598I538-A600 HydrophobicContact CG2-CB 4.35Å; V564-A600 HydrophobicContact CG1-CB 4.03Å; V564-A600 HydrophobicContact CG2-CB 3.95Å; L577-A600 HydrophobicContact CD1-CB 4.07Å; L577-A600 HydrophobicContact CD2-CB 4.04Å; R596-A600 WeakPolarHBondContact O-CB 3.4Å; R596-A600 PolarHBondContact O-N 3.4Å; I597-A600 PolarHBondContact O-N 2.89Å; I597-A600 VanDerWaalsContact O-N 3.13Å; N598-A600 PolarHBondContact O-N 3.15Å
601V96.3Very high94.5Very high3 Ų316.3 Ų16.32%0.0188%0.078CC..Hα-helixtrans-65.2-46.5179.6173.80000111I448 W451 I597 V599 R603 A604 I608 L626I448-V601 HydrophobicContact CG2-CG1 4.14Å; W451-V601 HydrophobicContact CE3-CB 4.22Å; W451-V601 HydrophobicContact CE3-CG1 3.79Å; W451-V601 HydrophobicContact CE3-CG2 4.35Å; W451-V601 HydrophobicContact CH2-CB 4.45Å; W451-V601 HydrophobicContact CH2-CG2 4.09Å; W451-V601 HydrophobicContact CZ3-CB 3.65Å; W451-V601 HydrophobicContact CZ3-CG1 3.77Å; W451-V601 HydrophobicContact CZ3-CG2 3.72Å; I597-V601 HydrophobicContact CG2-CG2 4.41Å; I597-V601 WeakPolarHBondContact O-CG2 3.44Å; I597-V601 PolarHBondContact O-N 2.96Å; V599-V601 PolarHBondContact O-N 3.26Å; V601-R603 PolarHBondContact O-N 3.45Å; V601-A604 PolarHBondContact O-N 2.86Å; V601-I608 HydrophobicContact CB-CD1 4.11Å; V601-I608 HydrophobicContact CG1-CD1 4.07Å; V601-I608 HydrophobicContact CG2-CD1 4.03Å; V601-L626 HydrophobicContact CG2-CD1 4.17Å; V601-L626 HydrophobicContact CG2-CD2 4.02Å
602T96.4Very high95.3Very high0 Ų016.2 Ų16.20%08%0.078CC..THydrogen-bonded Turntrans-7513.1-175.762.10000114.7P216 R443 M444 A452 N598 V599P216-T602 HydrophobicContact CB-CG2 4.13Å; P216-T602 HydrophobicContact CG-CG2 3.91Å; R443-T602 WeakPolarHBondContact CD-O 3.2Å; R443-T602 PolarHBondContact NH1-O 3.17Å; M444-T602 HydrophobicContact SD-CG2 3.79Å; A452-T602 HydrophobicContact CB-CG2 3.75Å; N598-T602 WeakPolarHBondContact O-CB 3.5Å; N598-T602 WeakPolarHBondContact O-CG2 3.4Å; N598-T602 PolarHBondContact O-N 3.29Å; N598-T602 PolarHBondContact O-OG1 2.99Å; V599-T602 PolarHBondContact O-N 3.35Å; V599-T602 PolarHBondContact O-OG1 3.13Å
603R95.6Very high95.8Very high4 Ų414.6 Ų14.62%0.0156%0.063CC..THydrogen-bonded Turntrans-85.6-23168.5-58.4-47.687.5179.815.3112.6I538 F567 R570 E571 K572 V575 V599 V601I538-R603 HydrophobicContact CD1-CB 3.99Å; I538-R603 HydrophobicContact CD1-CG 3.74Å; F567-R603 HydrophobicContact CD1-CB 4.03Å; F567-R603 HydrophobicContact CD1-CG 3.65Å; F567-R603 HydrophobicContact CE1-CB 4.17Å; F567-R603 HydrophobicContact CE1-CG 4.3Å; R570-R603 WeakPolarHBondContact O-CD 3.23Å; R570-R603 PolarHBondContact O-NH1 2.69Å; E571-R603 VanDerWaalsContact CA-O 3.29Å; E571-R603 WeakPolarHBondContact CA-O 3.39Å; K572-R603 PolarHBondContact N-O 3.41Å; V575-R603 HydrophobicContact CG2-CB 4Å; V599-R603 WeakPolarHBondContact O-CD 3.37Å; V599-R603 VanDerWaalsContact O-CG 3.23Å; V599-R603 WeakPolarHBondContact O-CG 3.49Å; V599-R603 PolarHBondContact O-N 2.95Å; V599-R603 PolarHBondContact O-NE 3.48Å; V601-R603 PolarHBondContact O-N 3.45Å
604A97.3Very high96.2Very high0 Ų012.5 Ų12.50%06%0.055CC..EExtended strand (participates in β ladder)trans-72.2150.317900000111.6M444 I448 K572 V575 V601 I608M444-A604 WeakPolarHBondContact CG-O 3.26Å; I448-A604 HydrophobicContact CD1-CB 4.12Å; I448-A604 HydrophobicContact CG2-CB 4.5Å; K572-A604 CarbonylContact O-C 3.57Å; V575-A604 HydrophobicContact CB-CB 4.07Å; V575-A604 HydrophobicContact CG2-CB 4.02Å; V601-A604 PolarHBondContact O-N 2.86Å; A604-I608 HydrophobicContact CB-CB 3.9Å
605R97.9Very high96.1Very high60 Ų6016.8 Ų16.823%0.2267%0.073CC..EExtended strand (participates in β ladder)trans-105.5-61.8168.1-66.8-17965.7-153.1-12110.9R443 M444 N445 H470 E571 K572 E573R443-R605 HydrophobicContact CG-CG 3.7Å; R443-R605 VanDerWaalsContact O-CA 3.26Å; R443-R605 WeakPolarHBondContact O-CA 3.33Å; R443-R605 VanDerWaalsContact O-CB 3.29Å; R443-R605 WeakPolarHBondContact O-CB 3.47Å; R443-R605 WeakPolarHBondContact O-CG 3.3Å; M444-R605 CarbonylContact C-O 3.59Å; M444-R605 WeakPolarHBondContact CA-O 3.46Å; N445-R605 PolarHBondContact N-O 3.19Å; H470-R605 PolarHBondContact NE2-O 2.86Å; E571-R605 IonicContact OE1-NE 3.2Å; K572-R605 WeakPolarHBondContact O-CB 3.21Å; K572-R605 WeakPolarHBondContact O-CG 3.45Å; K572-R605 PolarHBondContact O-N 2.83Å; E573-R605 IonicContact OE1-CZ 3.51Å; E573-R605 IonicContact OE1-NH1 3.82Å; E573-R605 PolarHBondContact OE1-NH1 3.1Å; E573-R605 IonicContact OE1-NH2 2.72Å; E573-R605 IonicContact OE2-CZ 2.69Å; E573-R605 IonicContact OE2-NE 3.5Å; E573-R605 IonicContact OE2-NH1 3.62Å
606R98.1Very high96.2Very high33 Ų3313.9 Ų13.913%0.1256%0.063CC..EExtended strand (participates in β ladder)trans-104.9-32-170.9-67.9166.6-175.2-87.5-10.2113.8H470 L471 L472 D474 P487 E573H470-R606 HydrophobicContact CB-CG 4.44Å; L471-R606 WeakPolarHBondContact O-CD 3.35Å; L471-R606 PolarHBondContact O-NH1 3.04Å; L472-R606 HydrophobicContact CD2-CB 3.95Å; L472-R606 HydrophobicContact CG-CB 4.17Å; D474-R606 IonicContact OD2-NH1 2.77Å; P487-R606 WeakPolarHBondContact CA-O 3.42Å; E573-R606 PolarHBondContact O-N 3.45Å; E573-R606 WeakPolarHBondContact OE2-CD 3.46Å; E573-R606 IonicContact OE2-NE 3.12Å; E573-R606 PolarHBondContact OE2-NE 3.18Å
607H98.2Very high96.3Very high0 Ų013.4 Ų13.40%06%0.061CC..EExtended strand (participates in β ladder)trans-147.8136.2-175.2176.291000111.8L472 E483 T486 P487 H521 E573 A574 V575L472-H607 HydrophobicContact CD1-CB 3.41Å; L472-H607 VanDerWaalsContact CD1-CB 3.41Å; L472-H607 HydrophobicContact CD2-CB 4.32Å; L472-H607 HydrophobicContact CG-CB 3.63Å; E483-H607 PolarHBondContact O-CE1 2.93Å; E483-H607 VanDerWaalsContact O-CE1 3.25Å; E483-H607 PolarHBondContact O-ND1 3.06Å; T486-H607 PolarHBondContact O-ND1 3.05Å; P487-H607 WeakPolarHBondContact O-CA 3.18Å; H521-H607 AromaticContact CE1-NE2 3.85Å; H521-H607 AromaticContact NE2-CE1 3.95Å; H521-H607 AromaticContact NE2-NE2 3.12Å; H521-H607 PolarHBondContact NE2-NE2 3.37Å; H521-H607 VanDerWaalsContact NE2-NE2 3.12Å; E573-H607 PolarHBondContact O-N 3.32Å; A574-H607 WeakPolarHBondContact CA-O 3.44Å; V575-H607 PolarHBondContact N-O 2.89Å
608I98.2Very high96.3Very high2 Ų218.9 Ų18.91%0.018%0.081CC..EExtended strand (participates in β ladder)trans-126.5128.9164.6-177.7168.6000111I448 P487 L488 L489 V575 V601 A604 V610I448-I608 HydrophobicContact CD1-CG2 4.21Å; I448-I608 HydrophobicContact CG1-CG2 4.13Å; I448-I608 HydrophobicContact CG2-CG2 4.41Å; P487-I608 PolarHBondContact O-N 3.49Å; L488-I608 HydrophobicContact CD2-CG2 3.54Å; L489-I608 PolarHBondContact N-O 2.74Å; V575-I608 WeakPolarHBondContact O-CA 3.42Å; V601-I608 HydrophobicContact CB-CD1 4.11Å; V601-I608 HydrophobicContact CG1-CD1 4.07Å; V601-I608 HydrophobicContact CG2-CD1 4.03Å; A604-I608 HydrophobicContact CB-CB 3.9Å; I608-V610 HydrophobicContact CD1-CG2 4.18Å; I608-V610 HydrophobicContact CG1-CG2 4.13Å
609A98.3Very high96.2Very high0 Ų023.9 Ų23.90%011%0.108CC..EExtended strand (participates in β ladder)trans-105.7128167.200000110L489 H521 V575 V576 L577L489-A609 HydrophobicContact CB-CB 4.24Å; L489-A609 HydrophobicContact CD2-CB 4.25Å; L489-A609 CarbonylContact O-C 3.54Å; L489-A609 WeakPolarHBondContact O-CA 3.28Å; H521-A609 WeakPolarHBondContact NE2-CB 3.34Å; V575-A609 PolarHBondContact O-N 3.05Å; V576-A609 CarbonylContact C-O 3.49Å; V576-A609 WeakPolarHBondContact CA-O 3.45Å; V576-A609 HydrophobicContact CG1-CB 4.27Å; V576-A609 HydrophobicContact CG2-CB 4.43Å; L577-A609 PolarHBondContact N-O 2.95Å
610V98.3Very high96.2Very high2 Ų226.1 Ų26.11%0.01212%0.118CC..EExtended strand (participates in β ladder)trans-111.3121174.8-179.50000108.7L489 L490 I491 L577 L579 I608 C612 M630L489-V610 PolarHBondContact O-N 3.41Å; L490-V610 HydrophobicContact CD1-CB 4.29Å; L490-V610 HydrophobicContact CD1-CG1 4.36Å; I491-V610 PolarHBondContact N-O 3.29Å; L577-V610 HydrophobicContact CB-CG2 4.33Å; L577-V610 HydrophobicContact CD2-CG2 4.29Å; L577-V610 WeakPolarHBondContact O-CA 3.42Å; L579-V610 HydrophobicContact CD1-CG1 4.1Å; L579-V610 HydrophobicContact CG-CG1 4.16Å; I608-V610 HydrophobicContact CD1-CG2 4.18Å; I608-V610 HydrophobicContact CG1-CG2 4.13Å; V610-C612 HydrophobicContact CG1-CB 4.43Å; V610-M630 HydrophobicContact CB-CE 4.07Å; V610-M630 HydrophobicContact CB-SD 3.94Å; V610-M630 HydrophobicContact CG2-CE 3.8Å; V610-M630 HydrophobicContact CG2-SD 3.53Å; V610-M630 VanDerWaalsContact CG2-SD 3.53Å
611V97.9Very high96.2Very high0 Ų029.9 Ų29.90%015%0.15CC..EExtended strand (participates in β ladder)trans-106.2117.8175.1-167.20000108.3I491 T493 E514 I517 V518 V576 L577 L579I491-V611 HydrophobicContact CB-CG1 4.46Å; I491-V611 HydrophobicContact CB-CG2 4.3Å; I491-V611 HydrophobicContact CD1-CG2 4.17Å; I491-V611 WeakPolarHBondContact O-CA 3.26Å; T493-V611 HydrophobicContact CG2-CG1 3.93Å; E514-V611 HydrophobicContact CB-CG1 4.26Å; E514-V611 HydrophobicContact CG-CG1 3.94Å; I517-V611 HydrophobicContact CB-CG1 4.14Å; I517-V611 HydrophobicContact CD1-CG1 4.15Å; I517-V611 HydrophobicContact CG2-CG1 3.8Å; I517-V611 HydrophobicContact CG2-CG2 4.17Å; V518-V611 HydrophobicContact CG2-CB 4.23Å; V518-V611 HydrophobicContact CG2-CG2 3.71Å; V576-V611 HydrophobicContact CG1-CG2 4.36Å; L577-V611 PolarHBondContact O-N 3.12Å; L579-V611 PolarHBondContact N-O 3.41Å
612C96.6Very high96.2Very high0 Ų030.5 Ų30.50%015%0.152CC..EExtended strand (participates in β ladder)trans-163.2160.6-176.3670000113.7I491 D492 T493 L579 V610 T614 V617I491-C612 PolarHBondContact O-N 2.83Å; D492-C612 WeakPolarHBondContact CA-O 3.49Å; T493-C612 PolarHBondContact N-O 2.99Å; T493-C612 PolarHBondContact OG1-O 3.24Å; L579-C612 HydrophobicContact CB-CB 3.77Å; L579-C612 HydrophobicContact CD1-CB 3.63Å; L579-C612 HydrophobicContact CG-CB 3.84Å; V610-C612 HydrophobicContact CG1-CB 4.43Å; C612-T614 PolarHBondContact O-N 2.87Å; C612-V617 HydrophobicContact CB-CG2 4.1Å
613D96.2Very high96.2Very high8 Ų830.5 Ų30.54%0.04315%0.152CC..  trans-85.6103.6168.1170.48.5000109.7T493 A494 S582 Q615 T616 V617T493-D613 VanDerWaalsContact OG1-CA 3.25Å; T493-D613 WeakPolarHBondContact OG1-CA 3.16Å; T493-D613 WeakPolarHBondContact OG1-CB 3.46Å; T493-D613 PolarHBondContact OG1-N 2.98Å; T493-D613 VanDerWaalsContact OG1-N 3.08Å; A494-D613 WeakPolarHBondContact CA-OD1 3.38Å; A494-D613 WeakPolarHBondContact CB-OD1 3.38Å; S582-D613 VanDerWaalsContact CA-OD2 3.31Å; S582-D613 WeakPolarHBondContact CA-OD2 3.46Å; S582-D613 VanDerWaalsContact CB-OD2 3.26Å; S582-D613 WeakPolarHBondContact CB-OD2 3.21Å; S582-D613 PolarHBondContact OG-OD2 3.06Å; D613-Q615 PolarHBondContact O-N 2.97Å; D613-Q615 VanDerWaalsContact OD1-CB 3.32Å; D613-Q615 WeakPolarHBondContact OD1-CB 3.37Å; D613-Q615 PolarHBondContact OD1-N 3.22Å; D613-T616 PolarHBondContact O-N 3.43Å; D613-T616 VanDerWaalsContact O-N 3.16Å; D613-T616 PolarHBondContact OD1-N 3.13Å; D613-T616 WeakPolarHBondContact OD2-CB 3.39Å; D613-T616 PolarHBondContact OD2-OG1 2.95Å; D613-V617 VanDerWaalsContact O-CB 3.31Å; D613-V617 WeakPolarHBondContact O-CB 3.29Å; D613-V617 VanDerWaalsContact O-CG2 3.31Å; D613-V617 WeakPolarHBondContact O-CG2 3.46Å; D613-V617 PolarHBondContact O-N 2.81Å
614T95.5Very high96.2Very high19 Ų1934.7 Ų34.712%0.11717%0.17CC..Hα-helixtrans-61.3-28.8-178.364.90000112.8L490 D492 C612 V617 R618 V627L490-T614 HydrophobicContact CD2-CG2 4.21Å; D492-T614 HydrophobicContact CB-CG2 4Å; D492-T614 VanDerWaalsContact CG-OG1 3.23Å; D492-T614 VanDerWaalsContact OD1-CG2 3.32Å; D492-T614 WeakPolarHBondContact OD1-CG2 3.38Å; D492-T614 PolarHBondContact OD1-N 2.93Å; D492-T614 PolarHBondContact OD1-OG1 3.41Å; D492-T614 WeakPolarHBondContact OD2-CG2 3.42Å; D492-T614 PolarHBondContact OD2-OG1 2.88Å; C612-T614 PolarHBondContact O-N 2.87Å; T614-V617 PolarHBondContact O-N 2.82Å; T614-R618 VanDerWaalsContact O-CB 3.27Å; T614-R618 WeakPolarHBondContact O-CB 3.48Å; T614-R618 WeakPolarHBondContact O-CG 3.33Å; T614-R618 PolarHBondContact O-N 3.29Å; T614-V627 HydrophobicContact CG2-CG1 3.82Å; T614-V627 HydrophobicContact CG2-CG2 4.43Å
615Q94.1Very high96.2Very high144 Ų14435.8 Ų35.867%0.67318%0.178SC*.Hα-helixtrans-68.9-35.5178.8-171.8177.215.900111.8A494 D613 N619A494-Q615 HydrophobicContact CB-CB 4.15Å; D613-Q615 PolarHBondContact O-N 2.97Å; D613-Q615 VanDerWaalsContact OD1-CB 3.32Å; D613-Q615 WeakPolarHBondContact OD1-CB 3.37Å; D613-Q615 PolarHBondContact OD1-N 3.22Å; Q615-N619 PolarHBondContact O-ND2 3.05Å
616T93.8Very high96.2Very high3 Ų333.2 Ų33.22%0.01817%0.169CC..Hα-helixtrans-78.7-43.2173.8-63.60000111.3R581 S582 N583 V588 D613 N619R581-T616 HydrophobicContact CB-CG2 4.13Å; R581-T616 WeakPolarHBondContact O-CB 3.08Å; R581-T616 WeakPolarHBondContact O-CG2 3.31Å; S582-T616 WeakPolarHBondContact CA-OG1 3.46Å; N583-T616 PolarHBondContact N-OG1 2.69Å; N583-T616 PolarHBondContact O-OG1 3.34Å; V588-T616 WeakPolarHBondContact CG1-O 3.37Å; D613-T616 PolarHBondContact O-N 3.43Å; D613-T616 VanDerWaalsContact O-N 3.16Å; D613-T616 PolarHBondContact OD1-N 3.13Å; D613-T616 WeakPolarHBondContact OD2-CB 3.39Å; D613-T616 PolarHBondContact OD2-OG1 2.95Å; T616-N619 PolarHBondContact O-ND2 3.15Å
617V93.9Very high96.1Very high1 Ų132 Ų321%0.00617%0.165CC..Hα-helixtrans-75.2-35.3-169.1168.40000113.4L579 C612 D613 T614 N619 H620 L623 V627L579-V617 HydrophobicContact CD1-CG1 3.93Å; L579-V617 HydrophobicContact CD1-CG2 4.08Å; C612-V617 HydrophobicContact CB-CG2 4.1Å; D613-V617 VanDerWaalsContact O-CB 3.31Å; D613-V617 WeakPolarHBondContact O-CB 3.29Å; D613-V617 VanDerWaalsContact O-CG2 3.31Å; D613-V617 WeakPolarHBondContact O-CG2 3.46Å; D613-V617 PolarHBondContact O-N 2.81Å; T614-V617 PolarHBondContact O-N 2.82Å; V617-N619 PolarHBondContact O-N 3.34Å; V617-N619 VanDerWaalsContact O-N 3.1Å; V617-H620 PolarHBondContact O-N 2.97Å; V617-L623 HydrophobicContact CG1-CB 3.59Å; V617-L623 HydrophobicContact CG1-CD1 4.05Å; V617-L623 HydrophobicContact CG1-CD2 4.43Å; V617-L623 HydrophobicContact CG1-CG 4.23Å; V617-V627 HydrophobicContact CG1-CG2 4.11Å
618R94.7Very high96.1Very high117 Ų11733.6 Ų33.644%0.44217%0.174SC..THydrogen-bonded Turntrans-68.6-5.8179.9-69.1176.692.6-168.95.6114.7T614 H620 K624 V627 D628T614-R618 VanDerWaalsContact O-CB 3.27Å; T614-R618 WeakPolarHBondContact O-CB 3.48Å; T614-R618 WeakPolarHBondContact O-CG 3.33Å; T614-R618 PolarHBondContact O-N 3.29Å; R618-H620 PolarHBondContact O-N 2.9Å; R618-K624 HydrophobicContact CB-CB 4.33Å; R618-K624 HydrophobicContact CB-CG 4.06Å; R618-K624 HydrophobicContact CG-CB 4.49Å; R618-K624 HydrophobicContact CG-CG 4.12Å; R618-V627 HydrophobicContact CG-CB 4.23Å; R618-V627 HydrophobicContact CG-CG1 3.98Å; R618-V627 HydrophobicContact CG-CG2 4.5Å; R618-D628 IonicContact CZ-OD1 3.42Å; R618-D628 VanDerWaalsContact CZ-OD1 3.29Å; R618-D628 IonicContact NE-OD1 2.86Å; R618-D628 PolarHBondContact NE-OD1 3.02Å; R618-D628 VanDerWaalsContact NE-OD1 3.16Å; R618-D628 IonicContact NH2-OD1 2.88Å; R618-D628 PolarHBondContact NH2-OD1 3.37Å; R618-D628 IonicContact NH2-OD2 3.41Å
619N93.9Very high96Very high106 Ų10634.3 Ų34.357%0.56718%0.177SC*.THydrogen-bonded Turntrans-72.4-12.7172.7-58.8-64.4000112.9G586 Q615 T616 V617G586-N619 VanDerWaalsContact CA-ND2 3.3Å; G586-N619 WeakPolarHBondContact CA-ND2 3.41Å; Q615-N619 PolarHBondContact O-ND2 3.05Å; T616-N619 PolarHBondContact O-ND2 3.15Å; V617-N619 PolarHBondContact O-N 3.34Å; V617-N619 VanDerWaalsContact O-N 3.1Å
620H94.8Very high96Very high46 Ų4634.4 Ų34.421%0.21318%0.178CC..SBendtrans-105.6126.2172.7-166.2-96.1000110.8V588 D594 V617 R618 F622 L623 K624V588-H620 HydrophobicContact CG1-CB 4.3Å; V588-H620 HydrophobicContact CG2-CB 3.91Å; D594-H620 IonicContact OD1-CE1 3.77Å; D594-H620 PolarHBondContact OD1-CE1 3.3Å; D594-H620 IonicContact OD1-ND1 2.73Å; V617-H620 PolarHBondContact O-N 2.97Å; R618-H620 PolarHBondContact O-N 2.9Å; H620-F622 PolarHBondContact O-N 3.2Å; H620-L623 HydrophobicContact CB-CB 4.16Å; H620-L623 HydrophobicContact CB-CD1 3.88Å; H620-L623 HydrophobicContact CB-CG 4.21Å; H620-L623 PolarHBondContact O-N 3.18Å; H620-L623 VanDerWaalsContact O-N 3.12Å; H620-K624 WeakPolarHBondContact O-CB 3.42Å; H620-K624 PolarHBondContact O-N 3.04Å
621A95.3Very high95.9Very high80 Ų8038 Ų3866%0.66120%0.2SC*.Hα-helixtrans-56.4-46.7-170.500000113.8L623 K624 S625A621-L623 PolarHBondContact O-N 3.05Å; A621-K624 WeakPolarHBondContact O-CB 3.43Å; A621-K624 PolarHBondContact O-N 2.85Å; A621-S625 PolarHBondContact O-N 3.24Å
622F95.4Very high95.8Very high15 Ų1545.4 Ų45.47%0.06623%0.234CC..Hα-helixtrans-69.9-29.1179.8-172.4-95.2000113.9W451 E455 M456 D594 I597 H620 S625 L626W451-F622 AromaticContact CH2-CE1 3.53Å; W451-F622 HydrophobicContact CH2-CE1 3.53Å; W451-F622 AromaticContact CH2-CZ 3.52Å; W451-F622 HydrophobicContact CH2-CZ 3.52Å; W451-F622 HydrophobicContact CZ2-CD1 4.18Å; W451-F622 AromaticContact CZ2-CE1 3.39Å; W451-F622 HydrophobicContact CZ2-CE1 3.39Å; W451-F622 HydrophobicContact CZ2-CE2 4.21Å; W451-F622 AromaticContact CZ2-CZ 3.4Å; W451-F622 HydrophobicContact CZ2-CZ 3.4Å; W451-F622 VanDerWaalsContact CZ2-CZ 3.4Å; E455-F622 HydrophobicContact CB-CD2 4.34Å; E455-F622 HydrophobicContact CB-CE2 3.67Å; E455-F622 HydrophobicContact CB-CZ 4.43Å; M456-F622 HydrophobicContact CE-CD2 4.41Å; M456-F622 HydrophobicContact CE-CE1 4.26Å; M456-F622 HydrophobicContact CE-CE2 3.53Å; M456-F622 HydrophobicContact CE-CZ 3.46Å; M456-F622 VanDerWaalsContact CE-CZ 3.46Å; M456-F622 HydrophobicContact CG-CE2 4.11Å; M456-F622 HydrophobicContact CG-CZ 4.05Å; D594-F622 HydrophobicContact CB-CB 4.39Å; D594-F622 HydrophobicContact CB-CD1 3.65Å; D594-F622 HydrophobicContact CB-CD2 3.94Å; D594-F622 HydrophobicContact CB-CE1 3.83Å; D594-F622 HydrophobicContact CB-CE2 4.08Å; D594-F622 HydrophobicContact CB-CG 3.72Å; D594-F622 HydrophobicContact CB-CZ 4.05Å; D594-F622 WeakPolarHBondContact OD1-CB 3.13Å; D594-F622 WeakPolarHBondContact OD1-CD1 3.23Å; D594-F622 VanDerWaalsContact OD1-CG 3.27Å; D594-F622 WeakPolarHBondContact OD1-CG 3.47Å; I597-F622 HydrophobicContact CB-CD1 4.33Å; I597-F622 HydrophobicContact CB-CE1 3.9Å; I597-F622 HydrophobicContact CG2-CD1 4.47Å; I597-F622 HydrophobicContact CG2-CE1 4.03Å; H620-F622 PolarHBondContact O-N 3.2Å; F622-S625 PolarHBondContact O-OG 3.15Å; F622-L626 PolarHBondContact O-N 3.08Å
623L95.6Very high95.7Very high1 Ų148.7 Ų48.71%0.00525%0.254CS..Hα-helixtrans-79.1-32.7174.4-68.9172000111.1L579 V588 L591 I597 V617 H620 A621 L626 V627L579-L623 HydrophobicContact CD1-CD2 4.44Å; V588-L623 HydrophobicContact CB-CD1 4.26Å; V588-L623 HydrophobicContact CG1-CD1 4.19Å; V588-L623 HydrophobicContact CG2-CD1 4.43Å; L591-L623 HydrophobicContact CB-CD1 3.91Å; L591-L623 HydrophobicContact CD1-CD1 4.32Å; I597-L623 HydrophobicContact CB-CD2 4.47Å; I597-L623 HydrophobicContact CD1-CD2 3.92Å; I597-L623 HydrophobicContact CG1-CD2 3.77Å; I597-L623 HydrophobicContact CG2-CD2 4Å; V617-L623 HydrophobicContact CG1-CB 3.59Å; V617-L623 HydrophobicContact CG1-CD1 4.05Å; V617-L623 HydrophobicContact CG1-CD2 4.43Å; V617-L623 HydrophobicContact CG1-CG 4.23Å; H620-L623 HydrophobicContact CB-CB 4.16Å; H620-L623 HydrophobicContact CB-CD1 3.88Å; H620-L623 HydrophobicContact CB-CG 4.21Å; H620-L623 PolarHBondContact O-N 3.18Å; H620-L623 VanDerWaalsContact O-N 3.12Å; A621-L623 PolarHBondContact O-N 3.05Å; L623-L626 PolarHBondContact O-N 3.01Å; L623-V627 WeakPolarHBondContact O-CG2 3.47Å; L623-V627 PolarHBondContact O-N 2.67Å
624K96.5Very high95.6Very high91 Ų9149.4 Ų49.440%0.39626%0.263SS..Hα-helixtrans-61.2-45.6171.5-169.9-163.8171.9-150.90110.6R618 H620 A621 L626 V627 D628R618-K624 HydrophobicContact CB-CB 4.33Å; R618-K624 HydrophobicContact CB-CG 4.06Å; R618-K624 HydrophobicContact CG-CB 4.49Å; R618-K624 HydrophobicContact CG-CG 4.12Å; H620-K624 WeakPolarHBondContact O-CB 3.42Å; H620-K624 PolarHBondContact O-N 3.04Å; A621-K624 WeakPolarHBondContact O-CB 3.43Å; A621-K624 PolarHBondContact O-N 2.85Å; K624-L626 VanDerWaalsContact C-N 3.3Å; K624-L626 PolarHBondContact O-N 2.85Å; K624-V627 PolarHBondContact O-N 2.82Å; K624-D628 WeakPolarHBondContact CE-OD2 3.2Å; K624-D628 WeakPolarHBondContact CG-OD2 3.35Å; K624-D628 IonicContact NZ-OD2 3.2Å; K624-D628 WeakPolarHBondContact O-CB 3.15Å; K624-D628 PolarHBondContact O-N 2.62Å
625S97.3Very high95.6Very high24 Ų2451.2 Ų51.217%0.16827%0.27CS..Hα-helixtrans-63.6-33.3177.666.50000113.1E455 A621 F622 H629E455-S625 VanDerWaalsContact CD-OG 3.3Å; E455-S625 WeakPolarHBondContact OE2-CB 3.34Å; E455-S625 PolarHBondContact OE2-OG 2.87Å; A621-S625 PolarHBondContact O-N 3.24Å; F622-S625 PolarHBondContact O-OG 3.15Å; S625-H629 VanDerWaalsContact O-CB 3.26Å; S625-H629 WeakPolarHBondContact O-CB 3.34Å; S625-H629 PolarHBondContact O-N 3.09Å
626L97Very high95.7Very high6 Ų647.5 Ų47.53%0.03126%0.257CS..Hα-helixtrans-64.5-48.7170.4178.961.7000112.3W451 I597 V601 F622 L623 K624 H629 M630W451-L626 HydrophobicContact CD2-CD1 3.74Å; W451-L626 HydrophobicContact CE3-CD1 4.13Å; W451-L626 HydrophobicContact CG-CD1 4.15Å; W451-L626 HydrophobicContact CH2-CD1 4.44Å; W451-L626 HydrophobicContact CZ2-CB 3.83Å; W451-L626 HydrophobicContact CZ2-CD1 4.06Å; W451-L626 HydrophobicContact CZ2-CD2 4.41Å; W451-L626 HydrophobicContact CZ2-CG 4.31Å; W451-L626 HydrophobicContact CZ3-CD1 4.48Å; W451-L626 VanDerWaalsContact NE1-CA 3.28Å; I597-L626 HydrophobicContact CG2-CD2 3.91Å; V601-L626 HydrophobicContact CG2-CD1 4.17Å; V601-L626 HydrophobicContact CG2-CD2 4.02Å; F622-L626 PolarHBondContact O-N 3.08Å; L623-L626 PolarHBondContact O-N 3.01Å; K624-L626 VanDerWaalsContact C-N 3.3Å; K624-L626 PolarHBondContact O-N 2.85Å; L626-H629 PolarHBondContact O-N 3.22Å; L626-M630 HydrophobicContact CD1-CG 4.15Å; L626-M630 HydrophobicContact CD1-SD 4.01Å; L626-M630 HydrophobicContact CG-SD 4.26Å; L626-M630 WeakPolarHBondContact O-CB 3.45Å; L626-M630 VanDerWaalsContact O-CG 3.3Å; L626-M630 WeakPolarHBondContact O-CG 3.17Å; L626-M630 PolarHBondContact O-N 3.38Å
627V97Very high95.8Very high6 Ų648.3 Ų48.34%0.03626%0.26CS..Hα-helixtrans-63-43.6178.9167.80000111.3L490 T614 V617 R618 L623 K624 M630 T631L490-V627 HydrophobicContact CD2-CG1 4.04Å; T614-V627 HydrophobicContact CG2-CG1 3.82Å; T614-V627 HydrophobicContact CG2-CG2 4.43Å; V617-V627 HydrophobicContact CG1-CG2 4.11Å; R618-V627 HydrophobicContact CG-CB 4.23Å; R618-V627 HydrophobicContact CG-CG1 3.98Å; R618-V627 HydrophobicContact CG-CG2 4.5Å; L623-V627 WeakPolarHBondContact O-CG2 3.47Å; L623-V627 PolarHBondContact O-N 2.67Å; K624-V627 PolarHBondContact O-N 2.82Å; V627-M630 PolarHBondContact O-N 2.82Å; V627-T631 WeakPolarHBondContact O-CB 3.41Å; V627-T631 PolarHBondContact O-N 2.89Å; V627-T631 PolarHBondContact O-OG1 3.26Å
628D97.6Very high95.8Very high35 Ų3550.5 Ų50.519%0.18727%0.273CS..Hα-helixtrans-64.8-47.3179.3-65.3-7.1000109.8R618 K624 M630 T631 E632R618-D628 IonicContact CZ-OD1 3.42Å; R618-D628 VanDerWaalsContact CZ-OD1 3.29Å; R618-D628 IonicContact NE-OD1 2.86Å; R618-D628 PolarHBondContact NE-OD1 3.02Å; R618-D628 VanDerWaalsContact NE-OD1 3.16Å; R618-D628 IonicContact NH2-OD1 2.88Å; R618-D628 PolarHBondContact NH2-OD1 3.37Å; R618-D628 IonicContact NH2-OD2 3.41Å; K624-D628 WeakPolarHBondContact CE-OD2 3.2Å; K624-D628 WeakPolarHBondContact CG-OD2 3.35Å; K624-D628 IonicContact NZ-OD2 3.2Å; K624-D628 WeakPolarHBondContact O-CB 3.15Å; K624-D628 PolarHBondContact O-N 2.62Å; D628-M630 PolarHBondContact O-N 3.44Å; D628-T631 WeakPolarHBondContact O-CA 3.38Å; D628-T631 WeakPolarHBondContact O-CB 3.48Å; D628-T631 PolarHBondContact O-N 2.85Å; D628-E632 WeakPolarHBondContact O-CG 3.33Å; D628-E632 PolarHBondContact O-N 3.3Å
629H97.4Very high95.7Very high17 Ų1744.9 Ų44.98%0.07925%0.252CS..Hα-helixtrans-59.4-43.5174.7-17892.2000113.3A447 E450 W451 S625 L626 T631 E632 V633A447-H629 PolarHBondContact O-NE2 3.44Å; E450-H629 IonicContact OE2-CE1 2.74Å; W451-H629 HydrophobicContact CB-CB 4.44Å; W451-H629 HydrophobicContact CG-CB 4.49Å; S625-H629 VanDerWaalsContact O-CB 3.26Å; S625-H629 WeakPolarHBondContact O-CB 3.34Å; S625-H629 PolarHBondContact O-N 3.09Å; L626-H629 PolarHBondContact O-N 3.22Å; H629-T631 PolarHBondContact O-N 3.33Å; H629-E632 PolarHBondContact O-N 3.33Å; H629-V633 PolarHBondContact O-N 3.37Å
630M97.1Very high95.5Very high2 Ų244.1 Ų44.11%0.0124%0.244CC..Hα-helixtrans-68.1-22.3176.2-69.5-172.977.500113.1L488 L489 L490 V610 L626 V627 D628 G634L488-M630 HydrophobicContact CB-CE 4.28Å; L488-M630 HydrophobicContact CD2-CE 4.44Å; L489-M630 VanDerWaalsContact C-CE 3.4Å; L489-M630 VanDerWaalsContact O-CE 3.23Å; L489-M630 WeakPolarHBondContact O-CE 3.42Å; L490-M630 HydrophobicContact CB-CB 4.23Å; L490-M630 HydrophobicContact CB-CE 4.27Å; V610-M630 HydrophobicContact CB-CE 4.07Å; V610-M630 HydrophobicContact CB-SD 3.94Å; V610-M630 HydrophobicContact CG2-CE 3.8Å; V610-M630 HydrophobicContact CG2-SD 3.53Å; V610-M630 VanDerWaalsContact CG2-SD 3.53Å; L626-M630 HydrophobicContact CD1-CG 4.15Å; L626-M630 HydrophobicContact CD1-SD 4.01Å; L626-M630 HydrophobicContact CG-SD 4.26Å; L626-M630 WeakPolarHBondContact O-CB 3.45Å; L626-M630 VanDerWaalsContact O-CG 3.3Å; L626-M630 WeakPolarHBondContact O-CG 3.17Å; L626-M630 PolarHBondContact O-N 3.38Å; V627-M630 PolarHBondContact O-N 2.82Å; D628-M630 PolarHBondContact O-N 3.44Å; M630-G634 CarbonylContact O-C 3.58Å; M630-G634 WeakPolarHBondContact O-CA 3.38Å; M630-G634 PolarHBondContact O-N 3.08Å; M630-G634 VanDerWaalsContact O-N 3.13Å
631T96.6Very high95.2Very high77 Ų7747.5 Ų47.547%0.47226%0.26SS..Hα-helixtrans-81.1-32.5174.2-55.70000112.1V627 D628 H629 V636V627-T631 WeakPolarHBondContact O-CB 3.41Å; V627-T631 PolarHBondContact O-N 2.89Å; V627-T631 PolarHBondContact O-OG1 3.26Å; D628-T631 WeakPolarHBondContact O-CA 3.38Å; D628-T631 WeakPolarHBondContact O-CB 3.48Å; D628-T631 PolarHBondContact O-N 2.85Å; H629-T631 PolarHBondContact O-N 3.33Å; T631-V636 HydrophobicContact CG2-CG2 4.22Å
632E95.8Very high94.8Very high156 Ų15645.1 Ų45.173%0.72923%0.234SC*.Hα-helixtrans-80-41.5179.2-71.8171.2-170.800113D628 H629D628-E632 WeakPolarHBondContact O-CG 3.33Å; D628-E632 PolarHBondContact O-N 3.3Å; H629-E632 PolarHBondContact O-N 3.33Å
633V94.4Very high94.2Very high69 Ų6946 Ų4642%0.41824%0.239SC..Hα-helixtrans-109.5-23.3-170.8-174.20000113A447 L488 H629A447-V633 HydrophobicContact CB-CG1 3.85Å; L488-V633 HydrophobicContact CD1-CB 4.13Å; L488-V633 HydrophobicContact CD1-CG1 4.14Å; H629-V633 PolarHBondContact O-N 3.37Å
634G93.5Very high92.8Very high22 Ų2255.2 Ų55.223%0.22728%0.282CS..SBendtrans-101.9-174-173.900000114.8M630M630-G634 CarbonylContact O-C 3.58Å; M630-G634 WeakPolarHBondContact O-CA 3.38Å; M630-G634 PolarHBondContact O-N 3.08Å; M630-G634 VanDerWaalsContact O-N 3.13Å
635E95.9Very high91Very high57 Ų5758.3 Ų58.327%0.26630%0.303SS..EExtended strand (participates in β ladder)trans-94.9136.9168.8-170.2-179166.200109.7T486 L488 L489 L490 R637T486-E635 HydrophobicContact CG2-CB 4.36Å; L488-E635 PolarHBondContact O-N 3.32Å; L489-E635 CarbonylContact C-O 3.58Å; L489-E635 WeakPolarHBondContact CA-O 3.48Å; L489-E635 HydrophobicContact CD1-CB 3.98Å; L489-E635 HydrophobicContact CD1-CG 4.12Å; L490-E635 PolarHBondContact N-O 3.25Å; E635-R637 IonicContact OE1-CZ 3.9Å; E635-R637 IonicContact OE1-NE 2.79Å; E635-R637 PolarHBondContact OE1-NE 3.2Å; E635-R637 IonicContact OE1-NH2 3.92Å; E635-R637 PolarHBondContact OE1-NH2 3.28Å; E635-R637 IonicContact OE2-NH2 2.71Å
636V96.5Very high89.1Confident67 Ų6758.9 Ų58.941%0.40630%0.304SS..EExtended strand (participates in β ladder)trans-117.2125.9176.1-172.80000109.8L490 T631L490-V636 HydrophobicContact CB-CG1 4.38Å; L490-V636 HydrophobicContact CB-CG2 4.24Å; L490-V636 HydrophobicContact CD2-CG1 4.13Å; L490-V636 HydrophobicContact CD2-CG2 4.26Å; L490-V636 HydrophobicContact CG-CG1 4.35Å; L490-V636 WeakPolarHBondContact O-CA 3.27Å; T631-V636 HydrophobicContact CG2-CG2 4.22Å
637R95.1Very high86.6Confident20 Ų2064.1 Ų64.18%0.07534%0.336CS..EExtended strand (participates in β ladder)trans-122.5151.4174.8-63.3-177-175.2-166-9.8110.1E482 E483 L489 L490 I491 D492 E635 E641 Y642E482-R637 VanDerWaalsContact CB-NH2 3.31Å; E482-R637 IonicContact OE2-CZ 3.8Å; E482-R637 IonicContact OE2-NH2 2.76Å; E482-R637 PolarHBondContact OE2-NH2 3.07Å; E483-R637 IonicContact OE1-CZ 3.52Å; E483-R637 IonicContact OE1-NH1 3.48Å; E483-R637 PolarHBondContact OE1-NH1 3.27Å; E483-R637 IonicContact OE1-NH2 3.13Å; L489-R637 HydrophobicContact CD1-CG 4.02Å; L490-R637 PolarHBondContact O-N 3.23Å; I491-R637 CarbonylContact C-O 3.54Å; I491-R637 WeakPolarHBondContact CA-O 3.09Å; D492-R637 PolarHBondContact N-O 2.77Å; E635-R637 IonicContact OE1-CZ 3.9Å; E635-R637 IonicContact OE1-NE 2.79Å; E635-R637 PolarHBondContact OE1-NE 3.2Å; E635-R637 IonicContact OE1-NH2 3.92Å; E635-R637 PolarHBondContact OE1-NH2 3.28Å; E635-R637 IonicContact OE2-NH2 2.71Å; R637-E641 WeakPolarHBondContact CA-OE1 3.32Å; R637-Y642 HydrophobicContact CB-CE2 4.07Å
638T94.5Very high84Confident46 Ų4667.6 Ų67.628%0.28236%0.359SS..EExtended strand (participates in β ladder)trans-97.2147.3171.8-178.80000111.6F640 E641T638-F640 HydrophobicContact CG2-CB 3.99Å; T638-F640 HydrophobicContact CG2-CD2 4.31Å; T638-F640 PolarHBondContact O-N 2.8Å; T638-F640 WeakPolarHBondContact OG1-CD2 3.43Å; T638-E641 HydrophobicContact CG2-CG 4.02Å; T638-E641 WeakPolarHBondContact CG2-OE1 3.43Å; T638-E641 PolarHBondContact N-OE1 2.62Å; T638-E641 WeakPolarHBondContact O-CB 3.33Å; T638-E641 PolarHBondContact O-N 2.78Å
639A91.9Very high81.2Confident0 Ų074.3 Ų74.30%039%0.389CS..Hα-helixtrans-57.5-21175.800000114.3D492 T493 C496 L498 I517 E641 Y642 L643D492-A639 WeakPolarHBondContact O-CB 3.37Å; D492-A639 PolarHBondContact O-N 3.03Å; T493-A639 HydrophobicContact CG2-CB 4.21Å; C496-A639 HydrophobicContact CB-CB 4.23Å; L498-A639 HydrophobicContact CD1-CB 3.9Å; I517-A639 HydrophobicContact CD1-CB 3.49Å; I517-A639 VanDerWaalsContact CD1-CB 3.49Å; I517-A639 HydrophobicContact CG1-CB 4.4Å; A639-E641 PolarHBondContact O-N 2.96Å; A639-Y642 PolarHBondContact O-N 2.71Å; A639-Y642 VanDerWaalsContact O-N 3.15Å; A639-L643 PolarHBondContact O-N 3.27Å
640F89.4Confident78.3Confident90 Ų9080.8 Ų80.840%0.39542%0.424SS..Hα-helixtrans-60.2-27171-70.2-70.6000113.5C496 T638 Y642 I646C496-F640 HydrophobicContact CB-CE2 4.5Å; C496-F640 HydrophobicContact CB-CZ 4.45Å; C496-F640 VanDerWaalsContact SG-CD2 3.54Å; C496-F640 WeakPolarHBondContact SG-CE2 3.29Å; T638-F640 HydrophobicContact CG2-CB 3.99Å; T638-F640 HydrophobicContact CG2-CD2 4.31Å; T638-F640 PolarHBondContact O-N 2.8Å; T638-F640 WeakPolarHBondContact OG1-CD2 3.43Å; F640-Y642 VanDerWaalsContact C-N 3.34Å; F640-I646 HydrophobicContact CD1-CB 4.11Å; F640-I646 HydrophobicContact CD1-CG2 4.09Å; F640-I646 HydrophobicContact CE1-CB 4.09Å; F640-I646 HydrophobicContact CE1-CG2 3.56Å; F640-I646 HydrophobicContact CZ-CG2 4.46Å
641E88.8Confident75.3Confident116 Ų11690.8 Ų90.854%0.54246%0.463SS..Hα-helixtrans-72.4-30.3176.5-64.8166.1-12100112R637 T638 A639R637-E641 WeakPolarHBondContact CA-OE1 3.32Å; T638-E641 HydrophobicContact CG2-CG 4.02Å; T638-E641 WeakPolarHBondContact CG2-OE1 3.43Å; T638-E641 PolarHBondContact N-OE1 2.62Å; T638-E641 WeakPolarHBondContact O-CB 3.33Å; T638-E641 PolarHBondContact O-N 2.78Å; A639-E641 PolarHBondContact O-N 2.96Å
642Y87.3Confident72.1Confident31 Ų3193.1 Ų93.112%0.12248%0.478CS..Hα-helixtrans-86.9-33-178.7-71.8-95.7000112.6I491 I517 L520 H521 R637 A639 F640I491-Y642 HydrophobicContact CD1-CE1 4.22Å; I491-Y642 HydrophobicContact CD1-CE2 3.97Å; I491-Y642 WeakPolarHBondContact CD1-OH 3.29Å; I491-Y642 HydrophobicContact CG1-CE2 4.12Å; I491-Y642 HydrophobicContact CG2-CD2 3.89Å; I491-Y642 HydrophobicContact CG2-CE2 3.71Å; I517-Y642 HydrophobicContact CG2-CD1 4.39Å; I517-Y642 HydrophobicContact CG2-CG 4.31Å; L520-Y642 HydrophobicContact CB-CD1 3.98Å; L520-Y642 HydrophobicContact CD1-CD1 4.48Å; L520-Y642 VanDerWaalsContact CD1-O 3.3Å; L520-Y642 WeakPolarHBondContact CD1-O 3.36Å; H521-Y642 HydrophobicContact CB-CE1 4.43Å; R637-Y642 HydrophobicContact CB-CE2 4.07Å; A639-Y642 PolarHBondContact O-N 2.71Å; A639-Y642 VanDerWaalsContact O-N 3.15Å; F640-Y642 VanDerWaalsContact C-N 3.34Å
643L83.4Confident68.8Low34 Ų3497.2 Ų97.218%0.17849%0.486CS..  trans-119.193.4-167.9-64.1173.5000112L498 D516 I517 L520 A639 D645 I646L498-L643 HydrophobicContact CD1-CD1 3.88Å; L498-L643 HydrophobicContact CD2-CD1 4.25Å; D516-L643 HydrophobicContact CB-CD2 4.3Å; I517-L643 HydrophobicContact CD1-CD1 4.22Å; I517-L643 HydrophobicContact CG1-CD1 3.85Å; I517-L643 HydrophobicContact CG1-CG 4.28Å; L520-L643 HydrophobicContact CD1-CD2 4.01Å; A639-L643 PolarHBondContact O-N 3.27Å; L643-D645 PolarHBondContact O-N 3.03Å; L643-I646 HydrophobicContact CB-CD1 3.65Å; L643-I646 HydrophobicContact CB-CG1 3.68Å; L643-I646 HydrophobicContact CD1-CD1 3.83Å; L643-I646 HydrophobicContact CD1-CG1 4.41Å; L643-I646 HydrophobicContact CG-CD1 4.38Å; L643-I646 PolarHBondContact O-N 2.97Å
644Q66.6Low65.6Low193 Ų193101.6 Ų101.690%0.90251%0.507SS*.THydrogen-bonded Turntrans-63.5-20.3-178.2-63.2-179.80.400114.2
645D58.7Low62.4Low156 Ų156111.8 Ų111.883%0.83454%0.539SS*.THydrogen-bonded Turntrans-91.10.5-176.6-66.5-41.4000114.3L643 V647L643-D645 PolarHBondContact O-N 3.03Å; D645-V647 VanDerWaalsContact C-N 3.31Å; D645-V647 PolarHBondContact O-N 2.99Å
646I57Low59.3Low36 Ų36118.7 Ų118.719%0.18557%0.568CS.*  trans-74.685.3176.6-53.2-177.6000110C496 L498 F640 L643 P648C496-I646 HydrophobicContact CB-CD1 4.03Å; L498-I646 HydrophobicContact CD1-CD1 4.4Å; L498-I646 HydrophobicContact CD2-CD1 4.22Å; L498-I646 HydrophobicContact CG-CD1 4.48Å; F640-I646 HydrophobicContact CD1-CB 4.11Å; F640-I646 HydrophobicContact CD1-CG2 4.09Å; F640-I646 HydrophobicContact CE1-CB 4.09Å; F640-I646 HydrophobicContact CE1-CG2 3.56Å; F640-I646 HydrophobicContact CZ-CG2 4.46Å; L643-I646 HydrophobicContact CB-CD1 3.65Å; L643-I646 HydrophobicContact CB-CG1 3.68Å; L643-I646 HydrophobicContact CD1-CD1 3.83Å; L643-I646 HydrophobicContact CD1-CG1 4.41Å; L643-I646 HydrophobicContact CG-CD1 4.38Å; L643-I646 PolarHBondContact O-N 2.97Å; I646-P648 VanDerWaalsContact O-CD 3.27Å; I646-P648 WeakPolarHBondContact O-CD 3.44Å
647V44.6Very low56.1Low117 Ų117123.1 Ų123.171%0.70959%0.59SS**  trans-66.4119.6168.5-1780000109.1D645 Q649D645-V647 VanDerWaalsContact C-N 3.31Å; D645-V647 PolarHBondContact O-N 2.99Å; V647-Q649 PolarHBondContact O-N 2.81Å
648P41.7Very low52.7Low79 Ų79128 Ų12851%0.51362%0.622SS.*  trans-65.5111.4177.4-20.433.5000110.5I646 N650I646-P648 VanDerWaalsContact O-CD 3.27Å; I646-P648 WeakPolarHBondContact O-CD 3.44Å; P648-N650 PolarHBondContact O-N 3.19Å
649Q40Very low49.4Very low176 Ų176136 Ų13682%0.82265%0.652SS**G310 helixtrans-66.9-1.2-177.9-67.3-173.9-3.800114.2V647V647-Q649 PolarHBondContact O-N 2.81Å
650N35.4Very low46.1Very low153 Ų153141.5 Ų141.582%0.81869%0.686SS**G310 helixtrans-937.2-171.6-67.7-18.3000115.2P648P648-N650 PolarHBondContact O-N 3.19Å
651Y33.4Very low42.9Very low212 Ų212144 Ų14483%0.83170%0.704SS**G310 helixtrans-117.76.9-176.9-89.2-79.2000116.9R653Y651-R653 PolarHBondContact O-N 3.37Å; Y651-R653 VanDerWaalsContact O-N 3.14Å
652T30.3Very low39.8Very low126 Ų126145.5 Ų145.577%0.77372%0.721SS**  trans-82.889167.8480000111.3D654T652-D654 PolarHBondContact O-N 3.01Å; T652-D654 VanDerWaalsContact O-N 3.16Å
653R27.5Very low36.7Very low242 Ų242149 Ų14991%0.91375%0.75SS**  trans-68.3103.3174.5-168.5177.4-170.9167.63.6110.3Y651 R655Y651-R653 PolarHBondContact O-N 3.37Å; Y651-R653 VanDerWaalsContact O-N 3.14Å; R653-R655 PolarHBondContact O-N 3.4Å; R653-R655 VanDerWaalsContact O-N 3.09Å
654D25.5Very low33.8Very low161 Ų161153.5 Ų153.586%0.86178%0.784SS**  trans-54.5112.5-177.7-103-26.7000112.6T652T652-D654 PolarHBondContact O-N 3.01Å; T652-D654 VanDerWaalsContact O-N 3.16Å
655R27.6Very low31.7Very low236 Ų236150.7 Ų150.789%0.89178%0.78SS**  trans-9399.4174.4-129.1-178.8-179.3-179.6-0.9108.6R653 D657R653-R655 PolarHBondContact O-N 3.4Å; R653-R655 VanDerWaalsContact O-N 3.09Å; R655-D657 PolarHBondContact O-N 3.37Å; R655-D657 VanDerWaalsContact O-N 3.15Å
656K29.9Very low30Very low201 Ų201148.7 Ų148.787%0.87478%0.779SS**  trans-64.3109.1169.9-75.2179.5176.7174.10109.8
657D30.2Very low28.4Very low161 Ų161152 Ų15286%0.86181%0.805SS**  trans-85133.1163.3-96-33.5000111.1R655R655-D657 PolarHBondContact O-N 3.37Å; R655-D657 VanDerWaalsContact O-N 3.15Å
658T23.8Very low27.3Very low122 Ų122156.5 Ų156.575%0.74882%0.815SS**  trans-90.5132.6-171.2-33.10000111
659K24.9Very low26.4Very low213 Ų213161.2 Ų161.293%0.92683%0.83SS**  trans-158.798159.4-111.2161.5-167.6175.90113.2
660T21.6Very low25.7Very low116 Ų116162.6 Ų162.671%0.71283%0.834SS**  trans-105.6157.3149.245.20000106.7
661N23.5Very low25.1Very low144 Ų144162.5 Ų162.577%0.7783%0.833SS**  cis-159.9146.8-2.9-111.8-10.8000106.7
662T23.4Very low24.6Very low147 Ų147163.2 Ų163.290%0.90283%0.834SS**  trans-154.1120.614410.80000112
663S22.1Very low24.3Very low105 Ų105163.1 Ų163.173%0.73483%0.829SS**  trans-54.1146.9178.549.30000117.3
664S22.8Very low24.1Very low127 Ų127159.6 Ų159.689%0.88882%0.823SS**  -146.4118.1129.160.30000111.5
665T22Very low23.9Very low134 Ų134156.3 Ų156.382%0.82282%0.818SS**  trans-104.7136.4178.9-14.80000109.5
666S23.1Very low24.4Very low114 Ų114151.4 Ų151.480%0.79782%0.817SS**  trans169.6155.5150.839.40000110.9
667S23.2Very low24.1Very low105 Ų105145.7 Ų145.773%0.73482%0.815SS**  cis-170.7151.4-36.445.50000107.3Q669S667-Q669 PolarHBondContact O-N 3.03Å
668K22.1Very low23.7Very low212 Ų212148.3 Ų148.392%0.92282%0.819SS**  trans-62.4131.4161.8-82.1179174.2175.80109.1
669Q22.7Very low23.7Very low179 Ų179147.1 Ų147.184%0.83682%0.821SS**  trans-67.4142.2159.9-70.5170.9-48.100109.9S667S667-Q669 PolarHBondContact O-N 3.03Å
670K24.3Very low23.6Very low205 Ų205144.9 Ų144.989%0.89181%0.811SS**  -162.3160116.5-108.9179.3-179.9-171.40112.1
671N24.4Very low23.7Very low151 Ų151147.1 Ų147.181%0.80781%0.813SS**  trans-73160.4-158.4-60.8-13.1000115.3
672R21.9Very low23.7Very low226 Ų226143.6 Ų143.685%0.85381%0.811SS**  trans-55.2150.4147.4-74.6170.6140.2174.4-8.9109.6
673D23.3Very low23.9Very low125 Ų125145.8 Ų145.867%0.66881%0.811SS**  -161.2150.972.5-98.9-52.4000115.1
674Q23.8Very low23.9Very low168 Ų168149.5 Ų149.579%0.78581%0.814SS**  trans38.5112.7143.9-62.4165.960.200119.7
675A22.1Very low23.9Very low92 Ų92148.8 Ų148.876%0.7681%0.805SS**  99.5174.169.200000112.1
676P38Very low24Very low133 Ų133148.6 Ų148.686%0.86480%0.803SS**  -128.7168.4-94.737-19.5000116.2
677G22.3Very low23.9Very low80 Ų80147.6 Ų147.683%0.82580%0.796SS**  trans-177.1150.8171.500000115.4
678K22.7Very low23.8Very low217 Ų217148 Ų14894%0.94380%0.799SS**  trans-116.7149.4-172.8-65.9173.7174.2175.70113.8
679A22.9Very low23.8Very low96 Ų96142.7 Ų142.779%0.79379%0.789SS**  trans-174.4118.1143.400000108.5
680K23.9Very low23.8Very low166 Ų166142.8 Ų142.872%0.72279%0.786SS**  90.3114.373.3-102.1-171.8172-92.90115.1
681E23.8Very low23.7Very low163 Ų163138.8 Ų138.876%0.76278%0.775SS**  trans52.8146.6132.7-65.3161.8172.600121.4
682G23.4Very low23.7Very low70 Ų70138.4 Ų138.472%0.72277%0.773SS**  cis-163156.22.100000111
683Q27Very low23.7Very low193 Ų193133.6 Ų133.690%0.90277%0.768SS**  98.9116.482.8-123-164.319.600115.6
684K22.6Very low23.7Very low184 Ų184132.2 Ų132.280%0.877%0.774SS**  179.1112.8129-102.6-178179.2-178.10111
685T22.9Very low23.7Very low112 Ų112128 Ų12869%0.68778%0.777SS**  64.5136.2104.660.80000114.8
686T22.6Very low23.8Very low129 Ų129128.5 Ų128.579%0.79177%0.774SS**  cis-173.8169.83.8160000107
687S22Very low23.2Very low94 Ų94130.7 Ų130.766%0.65777%0.773SS**  cis-171.1171-7.145.20000109.5
688S21.5Very low23.3Very low113 Ų113133 Ų13379%0.7977%0.766SS**  trans61.6143163.343.80000118.6
689S21.6Very low23.4Very low100 Ų100130.8 Ų130.870%0.69976%0.759SS**  cis-171148.3-0.3400000111.7
690K23Very low23.5Very low182 Ų182131.6 Ų131.679%0.79175%0.754SS**  trans54144.8141.4-70-172.7172.8-169.50120.4
691D22.6Very low23.5Very low120 Ų120133 Ų13364%0.64276%0.76SS**  cis-145.9145.3-2.5-89.4-41.8000106.8
692N22.9Very low23.7Very low144 Ų144130.2 Ų130.277%0.7776%0.758SS**  45.4127.181.6-74.9-22.5000113.3
693T23.4Very low24.3Very low124 Ų124135.9 Ų135.976%0.76177%0.766SS**  cis-149.7146.336.833.10000110.3
694A23.2Very low24.7Very low96 Ų96132.3 Ų132.379%0.79376%0.757SS**  54.2134.575.600000113.9
695G23.1Very low25.2Very low81 Ų81127.6 Ų127.684%0.83575%0.748SS**  cis-153.7-178.829.700000117.2
696S24Very low25.8Very low101 Ų101126.5 Ų126.571%0.70675%0.75SS**  trans-102.2154.8-1721740000111.1
697Q24.8Very low26.4Very low180 Ų180128.1 Ų128.184%0.84175%0.749SS**  -171.4136.5120-101.9171.93200115.2
698N25.3Very low27.1Very low127 Ų127130 Ų13068%0.67975%0.745SS**  trans-6.9136.7156-56.4-25.9000119.3
699H24.3Very low28.2Very low172 Ų172129.7 Ų129.780%0.79674%0.735SS**  -172.6138.797.8-104.5-76.8000114.6
700T25.1Very low29.3Very low112 Ų112132.9 Ų132.969%0.68774%0.739SS**  trans-10.7129.5154.747.30000119.5
701K25.3Very low30.4Very low197 Ų197132 Ų13286%0.85774%0.735SS**  177.5152.3119.7-98.4164.5-174.9176.80116.3
702S26.6Very low31.9Very low103 Ų103129.9 Ų129.972%0.7272%0.723SS**  trans62.2126.7148.156.40000123.2
703H36.4Very low33.5Very low189 Ų189127.2 Ų127.288%0.87571%0.709SS**  trans-50.6133.6150-71.2-96.5000112.4
704T34.6Very low35.3Very low118 Ų118129.5 Ų129.572%0.72471%0.708SS**  trans179104.1146.916.50000110.3
705S34Very low37.4Very low85 Ų85128 Ų12859%0.59469%0.692SS**  trans-148.6-26.3174.155.70000116Q707 K708S705-Q707 PolarHBondContact O-N 3Å; S705-Q707 VanDerWaalsContact O-N 3.08Å; S705-K708 WeakPolarHBondContact O-CB 3.47Å; S705-K708 PolarHBondContact O-N 3.29Å
706A35.3Very low39.8Very low90 Ų90129.3 Ų129.374%0.74467%0.672SS**THydrogen-bonded Turntrans-66-12.5178.600000115.2
707Q35.4Very low42.6Very low162 Ų162128 Ų12876%0.75765%0.651SS**THydrogen-bonded Turntrans-96.5-6.2170.6-75.9-178.4-20.100113.4S705S705-Q707 PolarHBondContact O-N 3Å; S705-Q707 VanDerWaalsContact O-N 3.08Å
708K37.3Very low45.2Very low133 Ų133122 Ų12258%0.57863%0.633SS**Hα-helixtrans-77.8-53-179.4-121.4177.6176.9-175.60110.7S705 Q710 K711 D712S705-K708 WeakPolarHBondContact O-CB 3.47Å; S705-K708 PolarHBondContact O-N 3.29Å; K708-Q710 VanDerWaalsContact C-N 3.32Å; K708-Q710 PolarHBondContact O-N 3.47Å; K708-Q710 VanDerWaalsContact O-N 3.15Å; K708-K711 CarbonylContact O-C 3.55Å; K708-K711 WeakPolarHBondContact O-CA 3.46Å; K708-K711 WeakPolarHBondContact O-CB 3.16Å; K708-K711 PolarHBondContact O-N 3.3Å; K708-D712 WeakPolarHBondContact O-CB 3.4Å; K708-D712 VanDerWaalsContact O-CG 3.29Å; K708-D712 PolarHBondContact O-N 3.35Å
709D43.9Very low47.9Very low108 Ų108121.3 Ų121.358%0.57863%0.626SS**Hα-helixtrans-58.5-35.4-174.3-53.8-28.8000114.5N713D709-N713 WeakPolarHBondContact O-CB 3.31Å; D709-N713 PolarHBondContact O-N 2.9Å
710Q44.1Very low50.7Low167 Ų167113.4 Ų113.478%0.7859%0.59SS**Hα-helixtrans-74.3-27.5174.4-78.5-170.2-300113.5K708K708-Q710 VanDerWaalsContact C-N 3.32Å; K708-Q710 PolarHBondContact O-N 3.47Å; K708-Q710 VanDerWaalsContact O-N 3.15Å
711K45.9Very low53.6Low163 Ų163110.3 Ų110.371%0.70957%0.566SS**Hα-helixtrans-79.8-40.6176.1-144.3175.8-174.7-175.20110.1K708 K714 S715K708-K711 CarbonylContact O-C 3.55Å; K708-K711 WeakPolarHBondContact O-CA 3.46Å; K708-K711 WeakPolarHBondContact O-CB 3.16Å; K708-K711 PolarHBondContact O-N 3.3Å; K711-K714 PolarHBondContact O-N 2.94Å; K711-S715 WeakPolarHBondContact O-CB 3.49Å; K711-S715 PolarHBondContact O-N 3.35Å
712D53.9Low56.4Low76 Ų76105.3 Ų105.341%0.40655%0.549SS..Hα-helixtrans-65.6-39.2177.9-65.1-17.7000111.5K708 S715 R716K708-D712 WeakPolarHBondContact O-CB 3.4Å; K708-D712 VanDerWaalsContact O-CG 3.29Å; K708-D712 PolarHBondContact O-N 3.35Å; D712-S715 WeakPolarHBondContact O-CB 3.31Å; D712-S715 PolarHBondContact O-N 3.06Å; D712-R716 WeakPolarHBondContact O-CB 3.25Å; D712-R716 PolarHBondContact O-N 3.46Å
713N57.2Low59.1Low87 Ų87104.7 Ų104.747%0.46553%0.534SS..Hα-helixtrans-65.8-37.8173.3-84-3000113.5D709 Y717D709-N713 WeakPolarHBondContact O-CB 3.31Å; D709-N713 PolarHBondContact O-N 2.9Å; N713-Y717 PolarHBondContact O-N 2.84Å
714K60.7Low61.3Low173 Ų17395.7 Ų95.775%0.75249%0.493SS*.Hα-helixtrans-70.1-35172.7-107.4-173.5174.3-172.60112K711 A718K711-K714 PolarHBondContact O-N 2.94Å; K714-A718 PolarHBondContact O-N 3.16Å
715S67.8Low63.7Low63 Ų6393.1 Ų93.144%0.44147%0.473SS..Hα-helixtrans-64.2-46.5174.5-159.50000111.2K711 D712 Y717 A718 E719K711-S715 WeakPolarHBondContact O-CB 3.49Å; K711-S715 PolarHBondContact O-N 3.35Å; D712-S715 WeakPolarHBondContact O-CB 3.31Å; D712-S715 PolarHBondContact O-N 3.06Å; S715-Y717 PolarHBondContact O-N 3.12Å; S715-A718 CarbonylContact O-C 3.6Å; S715-A718 PolarHBondContact O-N 3.27Å; S715-E719 PolarHBondContact O-N 2.94Å
716R74.6Confident66.1Low109 Ų10992.9 Ų92.941%0.41146%0.464SS..Hα-helixtrans-57.7-46.1177.1-113.1174.5157.878.42.9113.1D712 A718 E719 I720 D746D712-R716 WeakPolarHBondContact O-CB 3.25Å; D712-R716 PolarHBondContact O-N 3.46Å; R716-A718 VanDerWaalsContact C-N 3.33Å; R716-A718 PolarHBondContact O-N 3.15Å; R716-E719 PolarHBondContact O-N 3.44Å; R716-I720 WeakPolarHBondContact O-CG1 3.33Å; R716-I720 PolarHBondContact O-N 3Å; R716-D746 WeakPolarHBondContact CD-OD1 3.47Å; R716-D746 IonicContact CZ-OD2 3.35Å; R716-D746 VanDerWaalsContact NE-CG 3.33Å; R716-D746 IonicContact NE-OD1 3.15Å; R716-D746 PolarHBondContact NE-OD1 3.45Å; R716-D746 VanDerWaalsContact NE-OD1 3.15Å; R716-D746 IonicContact NE-OD2 2.85Å; R716-D746 PolarHBondContact NE-OD2 3.09Å; R716-D746 IonicContact NH2-OD2 2.95Å; R716-D746 PolarHBondContact NH2-OD2 3.06Å
717Y81.6Confident68.4Low73 Ų7388.8 Ų88.829%0.28643%0.43SS..Hα-helixtrans-60.6-44176.5179.3-88.4000111N713 S715 K721 L749 I753 E756N713-Y717 PolarHBondContact O-N 2.84Å; S715-Y717 PolarHBondContact O-N 3.12Å; Y717-K721 HydrophobicContact CE1-CD 3.89Å; Y717-K721 WeakPolarHBondContact O-CB 3.42Å; Y717-K721 PolarHBondContact O-N 2.66Å; Y717-L749 HydrophobicContact CD2-CD1 4.2Å; Y717-L749 HydrophobicContact CD2-CD2 3.92Å; Y717-L749 HydrophobicContact CD2-CG 4.5Å; Y717-L749 HydrophobicContact CE2-CD2 4.43Å; Y717-I753 HydrophobicContact CD2-CD1 3.83Å; Y717-I753 HydrophobicContact CD2-CG1 4.26Å; Y717-I753 HydrophobicContact CE2-CD1 3.72Å; Y717-I753 HydrophobicContact CE2-CG1 3.62Å; Y717-I753 HydrophobicContact CG-CD1 4.45Å; Y717-E756 PolarHBondContact OH-OE1 3.16Å; Y717-E756 PolarHBondContact OH-OE2 3.01Å; Y717-E756 VanDerWaalsContact OH-OE2 3.12Å
718A80.1Confident70.4Confident56 Ų5684.7 Ų84.746%0.46341%0.412SS..Hα-helixtrans-66.2-37.9176.400000113K714 S715 R716 L722K714-A718 PolarHBondContact O-N 3.16Å; S715-A718 CarbonylContact O-C 3.6Å; S715-A718 PolarHBondContact O-N 3.27Å; R716-A718 VanDerWaalsContact C-N 3.33Å; R716-A718 PolarHBondContact O-N 3.15Å; A718-L722 VanDerWaalsContact O-CB 3.24Å; A718-L722 WeakPolarHBondContact O-CB 3.5Å; A718-L722 PolarHBondContact O-N 2.97Å
719E81.3Confident72.4Confident111 Ų11185 Ų8552%0.51941%0.413SS..Hα-helixtrans-64.2-49.2175.5-104.6175.8158.700112.3S715 R716 K721 L722 Q723S715-E719 PolarHBondContact O-N 2.94Å; R716-E719 PolarHBondContact O-N 3.44Å; E719-K721 VanDerWaalsContact C-N 3.34Å; E719-L722 PolarHBondContact O-N 2.87Å; E719-Q723 WeakPolarHBondContact O-CG 3.24Å; E719-Q723 PolarHBondContact O-N 3.16Å
720I82.8Confident73.9Confident7 Ų784 Ų844%0.03641%0.407CS..Hα-helixtrans-63.9-43178.1-66169.2000109.8R716 Q723 V724 F738 F742 D746 I750 I753R716-I720 WeakPolarHBondContact O-CG1 3.33Å; R716-I720 PolarHBondContact O-N 3Å; I720-Q723 PolarHBondContact O-N 3.22Å; I720-V724 WeakPolarHBondContact O-CG2 3.27Å; I720-V724 PolarHBondContact O-N 2.92Å; I720-F738 HydrophobicContact CG2-CE1 4.43Å; I720-F738 HydrophobicContact CG2-CZ 4.48Å; I720-F742 HydrophobicContact CD1-CE1 4.19Å; I720-F742 HydrophobicContact CG1-CE1 4.43Å; I720-D746 HydrophobicContact CD1-CB 4.43Å; I720-I750 HydrophobicContact CG2-CG1 3.68Å; I720-I753 HydrophobicContact CB-CD1 4.14Å; I720-I753 HydrophobicContact CG2-CD1 3.76Å
721K86.2Confident75.1Confident46 Ų4681.4 Ų81.420%0.240%0.403CS..Hα-helixtrans-62.7-43.3176.9-170155.3-171.6154.40112Y717 E719 Q723 V724 E725 I753 E756Y717-K721 HydrophobicContact CE1-CD 3.89Å; Y717-K721 WeakPolarHBondContact O-CB 3.42Å; Y717-K721 PolarHBondContact O-N 2.66Å; E719-K721 VanDerWaalsContact C-N 3.34Å; K721-Q723 VanDerWaalsContact C-N 3.33Å; K721-Q723 PolarHBondContact O-N 3.2Å; K721-V724 PolarHBondContact O-N 2.85Å; K721-E725 WeakPolarHBondContact CE-OE1 3.21Å; K721-E725 HydrophobicContact CG-CG 4.38Å; K721-E725 WeakPolarHBondContact CG-OE1 3.41Å; K721-E725 WeakPolarHBondContact O-CB 3.4Å; K721-E725 WeakPolarHBondContact O-CG 3.26Å; K721-E725 PolarHBondContact O-N 2.88Å; K721-I753 HydrophobicContact CB-CD1 4.1Å; K721-I753 HydrophobicContact CB-CG2 4.24Å; K721-I753 HydrophobicContact CG-CG2 4.14Å; K721-E756 IonicContact NZ-OE2 3.45Å; K721-E756 PolarHBondContact NZ-OE2 3.22Å
722L85.8Confident76.1Confident92 Ų9280.8 Ų80.848%0.48241%0.407SS..Hα-helixtrans-64.1-35.5175.5-169.571.1000112.5A718 E719 N726A718-L722 VanDerWaalsContact O-CB 3.24Å; A718-L722 WeakPolarHBondContact O-CB 3.5Å; A718-L722 PolarHBondContact O-N 2.97Å; E719-L722 PolarHBondContact O-N 2.87Å; L722-N726 VanDerWaalsContact O-CB 3.26Å; L722-N726 WeakPolarHBondContact O-CB 3.31Å; L722-N726 PolarHBondContact O-N 2.97Å; L722-N726 PolarHBondContact O-ND2 3.47Å
723Q83.1Confident76.9Confident90 Ų9081.1 Ų81.142%0.42141%0.407SS..Hα-helixtrans-65.4-43174.5-73.7173.712.100112E719 I720 K721 F727E719-Q723 WeakPolarHBondContact O-CG 3.24Å; E719-Q723 PolarHBondContact O-N 3.16Å; I720-Q723 PolarHBondContact O-N 3.22Å; K721-Q723 VanDerWaalsContact C-N 3.33Å; K721-Q723 PolarHBondContact O-N 3.2Å; Q723-F727 PolarHBondContact O-N 3.28Å
724V82.8Confident77.6Confident0 Ų085.3 Ų85.30%042%0.422CS..Hα-helixtrans-68.9-41.8176179.50000111.4I720 K721 N726 F727 M728 L736 F738 I753 T754 L757 L759I720-V724 WeakPolarHBondContact O-CG2 3.27Å; I720-V724 PolarHBondContact O-N 2.92Å; K721-V724 PolarHBondContact O-N 2.85Å; V724-N726 PolarHBondContact O-N 3.08Å; V724-F727 WeakPolarHBondContact O-CB 3.39Å; V724-F727 PolarHBondContact O-N 3.31Å; V724-M728 WeakPolarHBondContact O-CG 3.46Å; V724-M728 PolarHBondContact O-N 2.87Å; V724-L736 HydrophobicContact CG2-CD2 4.38Å; V724-F738 HydrophobicContact CG2-CE2 4.38Å; V724-F738 HydrophobicContact CG2-CZ 4.03Å; V724-I753 HydrophobicContact CB-CG2 4.2Å; V724-I753 HydrophobicContact CG1-CG2 4.4Å; V724-I753 HydrophobicContact CG2-CG2 4.21Å; V724-T754 HydrophobicContact CG1-CG2 4Å; V724-T754 HydrophobicContact CG2-CG2 4.15Å; V724-L757 HydrophobicContact CB-CD1 4.37Å; V724-L757 HydrophobicContact CG1-CD1 3.71Å; V724-L759 HydrophobicContact CG1-CD1 3.51Å
725E83.9Confident78.5Confident65 Ų6581.5 Ų81.530%0.30441%0.41SS..Hα-helixtrans-65.5-35175.8-74.4177.7-167.400112.9K721 M728 K729 L757K721-E725 WeakPolarHBondContact CE-OE1 3.21Å; K721-E725 HydrophobicContact CG-CG 4.38Å; K721-E725 WeakPolarHBondContact CG-OE1 3.41Å; K721-E725 WeakPolarHBondContact O-CB 3.4Å; K721-E725 WeakPolarHBondContact O-CG 3.26Å; K721-E725 PolarHBondContact O-N 2.88Å; E725-M728 PolarHBondContact O-N 3.37Å; E725-K729 WeakPolarHBondContact O-CG 3.49Å; E725-K729 PolarHBondContact O-N 3.22Å; E725-K729 VanDerWaalsContact O-N 3.17Å; E725-L757 HydrophobicContact CG-CD1 4.31Å
726N83.6Confident79.3Confident79 Ų7979.7 Ų79.742%0.42240%0.395SS..Hα-helixtrans-69.5-38.4173.5-74.7-15.3000111.4L722 V724 M728 K729 D730L722-N726 VanDerWaalsContact O-CB 3.26Å; L722-N726 WeakPolarHBondContact O-CB 3.31Å; L722-N726 PolarHBondContact O-N 2.97Å; L722-N726 PolarHBondContact O-ND2 3.47Å; V724-N726 PolarHBondContact O-N 3.08Å; N726-M728 VanDerWaalsContact C-N 3.27Å; N726-M728 PolarHBondContact O-N 3.07Å; N726-K729 PolarHBondContact O-N 2.92Å; N726-D730 PolarHBondContact O-N 3.33Å
727F83.8Confident79.8Confident4 Ų480.7 Ų80.72%0.01840%0.404CS..Hα-helixtrans-61.1-32.5170.7167.4-102.7000112.8Q723 V724 M733 L736 L759 V774 R776Q723-F727 PolarHBondContact O-N 3.28Å; V724-F727 WeakPolarHBondContact O-CB 3.39Å; V724-F727 PolarHBondContact O-N 3.31Å; F727-M733 HydrophobicContact CD2-CB 4.05Å; F727-M733 HydrophobicContact CD2-CG 3.99Å; F727-M733 HydrophobicContact CD2-SD 4.09Å; F727-M733 HydrophobicContact CE2-CB 4.25Å; F727-M733 HydrophobicContact CE2-CG 4.21Å; F727-M733 WeakPolarHBondContact CE2-O 3.43Å; F727-L736 HydrophobicContact CB-CB 4.29Å; F727-L736 HydrophobicContact CB-CD2 3.93Å; F727-L736 HydrophobicContact CD1-CB 4.33Å; F727-L736 HydrophobicContact CD2-CB 3.71Å; F727-L736 HydrophobicContact CE2-CB 4.05Å; F727-L736 HydrophobicContact CG-CB 3.85Å; F727-L736 HydrophobicContact CG-CD2 4.31Å; F727-L759 HydrophobicContact CD1-CD1 4.33Å; F727-L759 HydrophobicContact CE1-CD1 4.44Å; F727-V774 HydrophobicContact CE1-CG1 4.32Å; F727-R776 HydrophobicContact CE1-CG 4.01Å; F727-R776 HydrophobicContact CZ-CG 4.09Å; F727-R776 PolarHBondContact O-NH2 3.48Å
728M78.8Confident80Confident76 Ų7677.5 Ų77.537%0.37439%0.392SS..Hα-helixtrans-69.8-31.6171.5-67.117877.300113V724 E725 N726 L757 L759 R776V724-M728 WeakPolarHBondContact O-CG 3.46Å; V724-M728 PolarHBondContact O-N 2.87Å; E725-M728 PolarHBondContact O-N 3.37Å; N726-M728 VanDerWaalsContact C-N 3.27Å; N726-M728 PolarHBondContact O-N 3.07Å; M728-L757 HydrophobicContact SD-CB 4.09Å; M728-L757 HydrophobicContact SD-CD1 4.08Å; M728-L757 HydrophobicContact SD-CD2 4.36Å; M728-L757 HydrophobicContact SD-CG 4.41Å; M728-L759 HydrophobicContact CG-CD1 3.9Å; M728-L759 HydrophobicContact CG-CD2 4.43Å; M728-L759 HydrophobicContact SD-CD1 4.11Å; M728-R776 VanDerWaalsContact C-NH2 3.28Å; M728-R776 PolarHBondContact O-NH2 3.19Å
729K78.5Confident79.9Confident141 Ų14178.1 Ų78.161%0.61339%0.391SS*.Hα-helixtrans-78.7-33.4178.9-69.8165.5-171.1161.60113.1E725 N726 V731E725-K729 WeakPolarHBondContact O-CG 3.49Å; E725-K729 PolarHBondContact O-N 3.22Å; E725-K729 VanDerWaalsContact O-N 3.17Å; N726-K729 PolarHBondContact O-N 2.92Å; K729-V731 PolarHBondContact O-N 3.48Å
730D76.4Confident79.5Confident85 Ų8575.2 Ų75.246%0.45538%0.383SS..  trans-86.598.3-179.7-162.5-20.3000111.7N726 N732 M733 R776N726-D730 PolarHBondContact O-N 3.33Å; D730-N732 PolarHBondContact O-N 3.36Å; D730-N732 PolarHBondContact OD1-N 2.74Å; D730-M733 HydrophobicContact CB-CB 4.49Å; D730-M733 PolarHBondContact O-N 3.39Å; D730-R776 PolarHBondContact O-NH2 3.28Å
731V68.9Low79.1Confident114 Ų11479.7 Ų79.769%0.69142%0.415SS*.THydrogen-bonded Turntrans-65.8-20.6-173.7-174.60000112.8K729K729-V731 PolarHBondContact O-N 3.48Å
732N66Low78.7Confident149 Ų14979.7 Ų79.780%0.79742%0.415SS*.THydrogen-bonded Turntrans-83.5-14.3-179.3-70.5-33.3000113.4D730D730-N732 PolarHBondContact O-N 3.36Å; D730-N732 PolarHBondContact OD1-N 2.74Å
733M72.1Confident78.1Confident83 Ų8378.9 Ų78.941%0.40941%0.411SS..  trans-91.3108.7-177.3-156.3174.5-170.300110.4F727 D730 L736F727-M733 HydrophobicContact CD2-CB 4.05Å; F727-M733 HydrophobicContact CD2-CG 3.99Å; F727-M733 HydrophobicContact CD2-SD 4.09Å; F727-M733 HydrophobicContact CE2-CB 4.25Å; F727-M733 HydrophobicContact CE2-CG 4.21Å; F727-M733 WeakPolarHBondContact CE2-O 3.43Å; D730-M733 HydrophobicContact CB-CB 4.49Å; D730-M733 PolarHBondContact O-N 3.39Å; M733-L736 HydrophobicContact CE-CD1 4.13Å
734K71.8Confident77.6Confident176 Ų17679.7 Ų79.777%0.76543%0.427SS*.  trans-77.7-37.3-175.8-67.6-170.2176.8-173.30114.3
735N79.1Confident77.3Confident93 Ų9384 Ų8450%0.49745%0.447SS..EExtended strand (participates in β ladder)trans-137.8139.9-178.1-63.8-41.7000110.5T773 V774 S775N735-T773 HydrophobicContact CB-CG2 3.97Å; N735-V774 CarbonylContact C-O 3.48Å; N735-V774 WeakPolarHBondContact CA-O 3.26Å; N735-S775 VanDerWaalsContact OD1-CB 3.24Å; N735-S775 WeakPolarHBondContact OD1-CB 3.49Å
736L85.2Confident77.1Confident25 Ų2581 Ų8113%0.13143%0.433CS..EExtended strand (participates in β ladder)trans-108.9130.6169.6-179.667.3000109.4V724 F727 M733 F738 T773 V774V724-L736 HydrophobicContact CG2-CD2 4.38Å; F727-L736 HydrophobicContact CB-CB 4.29Å; F727-L736 HydrophobicContact CB-CD2 3.93Å; F727-L736 HydrophobicContact CD1-CB 4.33Å; F727-L736 HydrophobicContact CD2-CB 3.71Å; F727-L736 HydrophobicContact CE2-CB 4.05Å; F727-L736 HydrophobicContact CG-CB 3.85Å; F727-L736 HydrophobicContact CG-CD2 4.31Å; M733-L736 HydrophobicContact CE-CD1 4.13Å; L736-F738 HydrophobicContact CD2-CE2 3.65Å; L736-F738 HydrophobicContact CD2-CZ 3.62Å; L736-F738 HydrophobicContact CG-CE2 3.96Å; L736-F738 HydrophobicContact CG-CZ 4.24Å; L736-T773 CarbonylContact O-C 3.57Å; L736-T773 WeakPolarHBondContact O-CA 3.48Å; L736-V774 HydrophobicContact CB-CB 4.4Å; L736-V774 PolarHBondContact N-O 3.46Å; L736-V774 PolarHBondContact O-N 3.06Å
737Q83.4Confident77.1Confident130 Ų13079.5 Ų79.561%0.60742%0.421SS*.EExtended strand (participates in β ladder)trans-118.9126.3-176.1-168.2-17816.700111.6C771 I772Q737-C771 HydrophobicContact CG-CB 4.22Å; Q737-C771 PolarHBondContact NE2-SG 3.24Å; Q737-I772 WeakPolarHBondContact CA-O 3.36Å
738F86Confident76.9Confident6 Ų683.7 Ų83.73%0.02644%0.444CS..EExtended strand (participates in β ladder)trans-98.9131.8175.3-66.8-89.1000111I720 V724 L736 F742 I750 C771 I772 V774I720-F738 HydrophobicContact CG2-CE1 4.43Å; I720-F738 HydrophobicContact CG2-CZ 4.48Å; V724-F738 HydrophobicContact CG2-CE2 4.38Å; V724-F738 HydrophobicContact CG2-CZ 4.03Å; L736-F738 HydrophobicContact CD2-CE2 3.65Å; L736-F738 HydrophobicContact CD2-CZ 3.62Å; L736-F738 HydrophobicContact CG-CE2 3.96Å; L736-F738 HydrophobicContact CG-CZ 4.24Å; F738-F742 AromaticContact CD1-CE1 3.9Å; F738-F742 HydrophobicContact CD1-CE1 3.9Å; F738-F742 HydrophobicContact CD1-CZ 4.04Å; F738-I750 HydrophobicContact CB-CD1 3.78Å; F738-I750 HydrophobicContact CD1-CD1 3.65Å; F738-I750 HydrophobicContact CD1-CG1 4.27Å; F738-I750 HydrophobicContact CD2-CD1 3.98Å; F738-I750 HydrophobicContact CD2-CG1 4.36Å; F738-I750 HydrophobicContact CD2-CG2 3.96Å; F738-I750 HydrophobicContact CE1-CD1 4.2Å; F738-I750 HydrophobicContact CE1-CG1 4.32Å; F738-I750 HydrophobicContact CE2-CD1 4.49Å; F738-I750 HydrophobicContact CE2-CG1 4.42Å; F738-I750 HydrophobicContact CE2-CG2 3.98Å; F738-I750 HydrophobicContact CG-CD1 3.52Å; F738-I750 HydrophobicContact CG-CG1 4.28Å; F738-I750 HydrophobicContact CZ-CG1 4.4Å; F738-C771 WeakPolarHBondContact O-CB 3.5Å; F738-I772 HydrophobicContact CB-CB 4.45Å; F738-I772 PolarHBondContact N-O 3.08Å; F738-I772 PolarHBondContact O-N 2.99Å; F738-V774 HydrophobicContact CD2-CG2 4.19Å; F738-V774 HydrophobicContact CE2-CG2 3.87Å
739P77.8Confident77.1Confident68 Ų6880.8 Ų80.844%0.44243%0.429SS..  trans-73.4158.6-171.529.1-34.9000113.3S741 F742P739-S741 PolarHBondContact O-N 3.34Å; P739-S741 VanDerWaalsContact O-N 3.13Å; P739-F742 HydrophobicContact CG-CD2 3.8Å; P739-F742 HydrophobicContact CG-CE2 3.68Å; P739-F742 PolarHBondContact O-N 3.17Å
740S74.3Confident77.3Confident50 Ų5074.1 Ų74.135%0.3540%0.4SS..THydrogen-bonded Turntrans-67.9-13.9-175.464.80000114.9F742 R747 G768 R770S740-F742 PolarHBondContact O-N 2.82Å; S740-R747 PolarHBondContact O-NH2 3.39Å; S740-G768 WeakPolarHBondContact CB-O 3.42Å; S740-G768 PolarHBondContact OG-O 2.63Å; S740-R770 WeakPolarHBondContact CA-O 3.37Å; S740-R770 VanDerWaalsContact CB-O 3.23Å; S740-R770 WeakPolarHBondContact CB-O 3.27Å
741S72.9Confident77.6Confident102 Ų10272.1 Ų72.171%0.71339%0.388SS*.THydrogen-bonded Turntrans-67-10.617553.70000114.6P739P739-S741 PolarHBondContact O-N 3.34Å; P739-S741 VanDerWaalsContact O-N 3.13Å
742F77.9Confident78.3Confident46 Ų4670.8 Ų70.820%0.20238%0.375CS..  trans-68.9131.1176.8-84.1-129.9000110.9I720 F738 P739 S740 D746 R747 I750I720-F742 HydrophobicContact CD1-CE1 4.19Å; I720-F742 HydrophobicContact CG1-CE1 4.43Å; F738-F742 AromaticContact CD1-CE1 3.9Å; F738-F742 HydrophobicContact CD1-CE1 3.9Å; F738-F742 HydrophobicContact CD1-CZ 4.04Å; P739-F742 HydrophobicContact CG-CD2 3.8Å; P739-F742 HydrophobicContact CG-CE2 3.68Å; P739-F742 PolarHBondContact O-N 3.17Å; S740-F742 PolarHBondContact O-N 2.82Å; F742-D746 HydrophobicContact CB-CB 4.26Å; F742-D746 HydrophobicContact CD1-CB 3.64Å; F742-D746 HydrophobicContact CE1-CB 4.39Å; F742-D746 HydrophobicContact CG-CB 4.29Å; F742-R747 HydrophobicContact CB-CG 4.16Å; F742-R747 PolarHBondContact O-NE 2.92Å; F742-I750 HydrophobicContact CD1-CD1 3.64Å; F742-I750 HydrophobicContact CE1-CD1 3.95Å
743N74.6Confident79.2Confident75 Ų7563.7 Ų63.740%0.40134%0.337SS..  trans-73.2169.4179.971.757.7000111.6H745 D746 R747N743-H745 PolarHBondContact O-N 3.48Å; N743-H745 VanDerWaalsContact O-N 3.17Å; N743-H745 WeakPolarHBondContact OD1-CA 3.48Å; N743-H745 WeakPolarHBondContact OD1-CB 3.32Å; N743-H745 PolarHBondContact OD1-N 2.98Å; N743-D746 VanDerWaalsContact ND2-CG 3.27Å; N743-D746 PolarHBondContact ND2-OD1 3.15Å; N743-D746 PolarHBondContact ND2-OD2 3.49Å; N743-D746 PolarHBondContact O-N 2.72Å; N743-D746 PolarHBondContact OD1-N 2.87Å; N743-R747 WeakPolarHBondContact O-CG 3.3Å; N743-R747 PolarHBondContact O-N 2.97Å
744S72Confident79.7Confident107 Ų10759.8 Ų59.875%0.74832%0.317SS*.Hα-helixtrans-58.8-29.5-176.1-44.20000114.6L748S744-L748 PolarHBondContact O-N 2.91Å
745H76.4Confident80.2Confident89 Ų8958.3 Ų58.341%0.41231%0.313SS..Hα-helixtrans-78.4-45.4177.5177-85.7000111.2N743 R747 L748 L749N743-H745 PolarHBondContact O-N 3.48Å; N743-H745 VanDerWaalsContact O-N 3.17Å; N743-H745 WeakPolarHBondContact OD1-CA 3.48Å; N743-H745 WeakPolarHBondContact OD1-CB 3.32Å; N743-H745 PolarHBondContact OD1-N 2.98Å; H745-R747 PolarHBondContact O-N 2.97Å; H745-L748 WeakPolarHBondContact O-CB 3.46Å; H745-L748 PolarHBondContact O-N 2.96Å; H745-L748 VanDerWaalsContact O-N 3.11Å; H745-L749 WeakPolarHBondContact O-CG 3.32Å; H745-L749 PolarHBondContact O-N 3.11Å
746D80.4Confident80.4Confident3 Ų359.3 Ų59.32%0.01632%0.315CS..Hα-helixtrans-61.6-35.7176.5-61.8-10.1000110.9R716 I720 F742 N743 L749 I750R716-D746 WeakPolarHBondContact CD-OD1 3.47Å; R716-D746 IonicContact CZ-OD2 3.35Å; R716-D746 VanDerWaalsContact NE-CG 3.33Å; R716-D746 IonicContact NE-OD1 3.15Å; R716-D746 PolarHBondContact NE-OD1 3.45Å; R716-D746 VanDerWaalsContact NE-OD1 3.15Å; R716-D746 IonicContact NE-OD2 2.85Å; R716-D746 PolarHBondContact NE-OD2 3.09Å; R716-D746 IonicContact NH2-OD2 2.95Å; R716-D746 PolarHBondContact NH2-OD2 3.06Å; I720-D746 HydrophobicContact CD1-CB 4.43Å; F742-D746 HydrophobicContact CB-CB 4.26Å; F742-D746 HydrophobicContact CD1-CB 3.64Å; F742-D746 HydrophobicContact CE1-CB 4.39Å; F742-D746 HydrophobicContact CG-CB 4.29Å; N743-D746 VanDerWaalsContact ND2-CG 3.27Å; N743-D746 PolarHBondContact ND2-OD1 3.15Å; N743-D746 PolarHBondContact ND2-OD2 3.49Å; N743-D746 PolarHBondContact O-N 2.72Å; N743-D746 PolarHBondContact OD1-N 2.87Å; D746-L749 PolarHBondContact O-N 3.45Å; D746-I750 WeakPolarHBondContact O-CG1 3.4Å; D746-I750 PolarHBondContact O-N 2.78Å; D746-I750 VanDerWaalsContact O-N 3.13Å
747R82Confident80.2Confident47 Ų4760.4 Ų60.418%0.17732%0.321CS..Hα-helixtrans-64.1-43.1172.2-70.2173.7-178.2-102.15.9112.9S740 F742 N743 H745 L749 I750 H751 R770 I772S740-R747 PolarHBondContact O-NH2 3.39Å; F742-R747 HydrophobicContact CB-CG 4.16Å; F742-R747 PolarHBondContact O-NE 2.92Å; N743-R747 WeakPolarHBondContact O-CG 3.3Å; N743-R747 PolarHBondContact O-N 2.97Å; H745-R747 PolarHBondContact O-N 2.97Å; R747-L749 VanDerWaalsContact C-N 3.33Å; R747-I750 PolarHBondContact O-N 2.88Å; R747-H751 PolarHBondContact O-CD2 2.9Å; R747-H751 PolarHBondContact O-N 3.47Å; R747-R770 PolarHBondContact NH1-O 3.37Å; R747-R770 PolarHBondContact NH2-O 3.29Å; R747-I772 HydrophobicContact CB-CD1 3.86Å; R747-I772 HydrophobicContact CG-CD1 3.84Å
748L80.3Confident80Confident93 Ų9356.8 Ų56.849%0.48732%0.318SS..Hα-helixtrans-61.4-42.3175.7-175.372.8000111.2S744 H745 I750 H751 Q752S744-L748 PolarHBondContact O-N 2.91Å; H745-L748 WeakPolarHBondContact O-CB 3.46Å; H745-L748 PolarHBondContact O-N 2.96Å; H745-L748 VanDerWaalsContact O-N 3.11Å; L748-I750 PolarHBondContact O-N 2.96Å; L748-H751 PolarHBondContact O-N 3.03Å; L748-Q752 WeakPolarHBondContact O-CG 3.31Å; L748-Q752 PolarHBondContact O-N 3.08Å
749L83.3Confident79.8Confident15 Ų1557.4 Ų57.48%0.07932%0.321CS..Hα-helixtrans-63.1-39.9177.4-68.2-173.4000112.6Y717 H745 D746 R747 H751 Q752 I753Y717-L749 HydrophobicContact CD2-CD1 4.2Å; Y717-L749 HydrophobicContact CD2-CD2 3.92Å; Y717-L749 HydrophobicContact CD2-CG 4.5Å; Y717-L749 HydrophobicContact CE2-CD2 4.43Å; H745-L749 WeakPolarHBondContact O-CG 3.32Å; H745-L749 PolarHBondContact O-N 3.11Å; D746-L749 PolarHBondContact O-N 3.45Å; R747-L749 VanDerWaalsContact C-N 3.33Å; L749-H751 PolarHBondContact O-N 2.97Å; L749-Q752 PolarHBondContact O-N 2.95Å; L749-I753 HydrophobicContact CB-CD1 4.44Å; L749-I753 WeakPolarHBondContact O-CB 3.48Å; L749-I753 WeakPolarHBondContact O-CD1 3.43Å; L749-I753 WeakPolarHBondContact O-CG1 3.39Å; L749-I753 PolarHBondContact O-N 3.38Å
750I83.6Confident80.1Confident0 Ų057.7 Ų57.70%032%0.322CS..Hα-helixtrans-60-46.9176-67.9159000110.4I720 F738 F742 D746 R747 L748 I753 T754 I772 V774I720-I750 HydrophobicContact CG2-CG1 3.68Å; F738-I750 HydrophobicContact CB-CD1 3.78Å; F738-I750 HydrophobicContact CD1-CD1 3.65Å; F738-I750 HydrophobicContact CD1-CG1 4.27Å; F738-I750 HydrophobicContact CD2-CD1 3.98Å; F738-I750 HydrophobicContact CD2-CG1 4.36Å; F738-I750 HydrophobicContact CD2-CG2 3.96Å; F738-I750 HydrophobicContact CE1-CD1 4.2Å; F738-I750 HydrophobicContact CE1-CG1 4.32Å; F738-I750 HydrophobicContact CE2-CD1 4.49Å; F738-I750 HydrophobicContact CE2-CG1 4.42Å; F738-I750 HydrophobicContact CE2-CG2 3.98Å; F738-I750 HydrophobicContact CG-CD1 3.52Å; F738-I750 HydrophobicContact CG-CG1 4.28Å; F738-I750 HydrophobicContact CZ-CG1 4.4Å; F742-I750 HydrophobicContact CD1-CD1 3.64Å; F742-I750 HydrophobicContact CE1-CD1 3.95Å; D746-I750 WeakPolarHBondContact O-CG1 3.4Å; D746-I750 PolarHBondContact O-N 2.78Å; D746-I750 VanDerWaalsContact O-N 3.13Å; R747-I750 PolarHBondContact O-N 2.88Å; L748-I750 PolarHBondContact O-N 2.96Å; I750-I753 PolarHBondContact O-N 2.91Å; I750-T754 WeakPolarHBondContact O-CB 3.33Å; I750-T754 WeakPolarHBondContact O-CG2 3.21Å; I750-T754 PolarHBondContact O-N 3.25Å; I750-T754 PolarHBondContact O-OG1 3.22Å; I750-I772 HydrophobicContact CB-CD1 4.44Å; I750-I772 HydrophobicContact CD1-CD1 4.33Å; I750-I772 HydrophobicContact CG2-CD1 4.46Å; I750-I772 HydrophobicContact CG2-CG2 3.87Å; I750-V774 HydrophobicContact CG2-CG2 4.19Å
751H82.7Confident80.7Confident44 Ų4458.5 Ų58.520%0.20432%0.32CS..Hα-helixtrans-59.5-50.5176.8-74.3-62.8000111.7R747 L748 L749 I753 T754 E755 H761R747-H751 PolarHBondContact O-CD2 2.9Å; R747-H751 PolarHBondContact O-N 3.47Å; L748-H751 PolarHBondContact O-N 3.03Å; L749-H751 PolarHBondContact O-N 2.97Å; H751-I753 PolarHBondContact O-N 3.29Å; H751-T754 PolarHBondContact O-N 3.14Å; H751-T754 PolarHBondContact O-OG1 3.21Å; H751-T754 VanDerWaalsContact O-OG1 3.12Å; H751-E755 WeakPolarHBondContact O-CB 3.49Å; H751-E755 PolarHBondContact O-N 3Å; H751-H761 AromaticContact CE1-CE1 3.97Å; H751-H761 AromaticContact CE1-CG 3.95Å; H751-H761 AromaticContact CE1-ND1 3.56Å; H751-H761 AromaticContact ND1-CD2 3.5Å; H751-H761 AromaticContact ND1-CE1 3.22Å; H751-H761 PolarHBondContact ND1-CE1 2.86Å; H751-H761 AromaticContact ND1-CG 3.27Å; H751-H761 VanDerWaalsContact ND1-CG 3.27Å; H751-H761 AromaticContact ND1-ND1 3.08Å; H751-H761 PolarHBondContact ND1-ND1 3.33Å; H751-H761 AromaticContact ND1-NE2 3.42Å; H751-H761 PolarHBondContact ND1-NE2 2.98Å
752Q83.4Confident81.1Confident86 Ų8658 Ų5840%0.40231%0.306SS..Hα-helixtrans-60-44.6178.5-71.4-179.1-36.600113.2L748 L749 T754 E756L748-Q752 WeakPolarHBondContact O-CG 3.31Å; L748-Q752 PolarHBondContact O-N 3.08Å; L749-Q752 PolarHBondContact O-N 2.95Å; Q752-T754 VanDerWaalsContact C-N 3.33Å; Q752-T754 PolarHBondContact O-N 3.19Å; Q752-E756 VanDerWaalsContact O-CB 3.32Å; Q752-E756 WeakPolarHBondContact O-CB 3.42Å; Q752-E756 VanDerWaalsContact O-CG 3.31Å; Q752-E756 WeakPolarHBondContact O-CG 3.26Å; Q752-E756 PolarHBondContact O-N 3.16Å
753I84.7Confident81.2Confident0 Ų057.6 Ų57.60%031%0.309CS..Hα-helixtrans-67.2-34.7-179.8-70.3164000111.5Y717 I720 K721 V724 L749 I750 H751 L757Y717-I753 HydrophobicContact CD2-CD1 3.83Å; Y717-I753 HydrophobicContact CD2-CG1 4.26Å; Y717-I753 HydrophobicContact CE2-CD1 3.72Å; Y717-I753 HydrophobicContact CE2-CG1 3.62Å; Y717-I753 HydrophobicContact CG-CD1 4.45Å; I720-I753 HydrophobicContact CB-CD1 4.14Å; I720-I753 HydrophobicContact CG2-CD1 3.76Å; K721-I753 HydrophobicContact CB-CD1 4.1Å; K721-I753 HydrophobicContact CB-CG2 4.24Å; K721-I753 HydrophobicContact CG-CG2 4.14Å; V724-I753 HydrophobicContact CB-CG2 4.2Å; V724-I753 HydrophobicContact CG1-CG2 4.4Å; V724-I753 HydrophobicContact CG2-CG2 4.21Å; L749-I753 HydrophobicContact CB-CD1 4.44Å; L749-I753 WeakPolarHBondContact O-CB 3.48Å; L749-I753 WeakPolarHBondContact O-CD1 3.43Å; L749-I753 WeakPolarHBondContact O-CG1 3.39Å; L749-I753 PolarHBondContact O-N 3.38Å; I750-I753 PolarHBondContact O-N 2.91Å; H751-I753 PolarHBondContact O-N 3.29Å; I753-L757 HydrophobicContact CG2-CD1 3.95Å; I753-L757 WeakPolarHBondContact O-CB 3.19Å; I753-L757 WeakPolarHBondContact O-CD1 3.46Å; I753-L757 VanDerWaalsContact O-CG 3.24Å; I753-L757 WeakPolarHBondContact O-CG 3.27Å; I753-L757 PolarHBondContact O-N 3.47Å
754T82.1Confident81.1Confident0 Ų060.8 Ų60.80%032%0.316CS..Hα-helixtrans-79.1-34.6-179.445.20000112.3V724 I750 H751 Q752 L757 G758 L759 H761 V774V724-T754 HydrophobicContact CG1-CG2 4Å; V724-T754 HydrophobicContact CG2-CG2 4.15Å; I750-T754 WeakPolarHBondContact O-CB 3.33Å; I750-T754 WeakPolarHBondContact O-CG2 3.21Å; I750-T754 PolarHBondContact O-N 3.25Å; I750-T754 PolarHBondContact O-OG1 3.22Å; H751-T754 PolarHBondContact O-N 3.14Å; H751-T754 PolarHBondContact O-OG1 3.21Å; H751-T754 VanDerWaalsContact O-OG1 3.12Å; Q752-T754 VanDerWaalsContact C-N 3.33Å; Q752-T754 PolarHBondContact O-N 3.19Å; T754-L757 CarbonylContact O-C 3.59Å; T754-L757 PolarHBondContact O-N 3.14Å; T754-G758 PolarHBondContact O-N 3.07Å; T754-G758 VanDerWaalsContact O-N 3.13Å; T754-L759 PolarHBondContact O-N 3.1Å; T754-H761 PolarHBondContact OG1-CD2 3.22Å; T754-V774 HydrophobicContact CG2-CB 4.25Å; T754-V774 HydrophobicContact CG2-CG1 3.47Å; T754-V774 VanDerWaalsContact CG2-CG1 3.47Å; T754-V774 HydrophobicContact CG2-CG2 3.7Å
755E83.2Confident80.9Confident146 Ų14658.2 Ų58.268%0.68231%0.306SS*.Hα-helixtrans-65.1-45.3168.6-169.3173.3-154.200111.5H751 L757 G758H751-E755 WeakPolarHBondContact O-CB 3.49Å; H751-E755 PolarHBondContact O-N 3Å; E755-L757 PolarHBondContact O-N 2.68Å; E755-G758 PolarHBondContact O-N 2.98Å
756E83.1Confident79.6Confident114 Ų11462.8 Ų62.853%0.53333%0.328SS..Hα-helixtrans-55.6-30.4172.4-84.4178.8-160.400113.5Y717 K721 Q752Y717-E756 PolarHBondContact OH-OE1 3.16Å; Y717-E756 PolarHBondContact OH-OE2 3.01Å; Y717-E756 VanDerWaalsContact OH-OE2 3.12Å; K721-E756 IonicContact NZ-OE2 3.45Å; K721-E756 PolarHBondContact NZ-OE2 3.22Å; Q752-E756 VanDerWaalsContact O-CB 3.32Å; Q752-E756 WeakPolarHBondContact O-CB 3.42Å; Q752-E756 VanDerWaalsContact O-CG 3.31Å; Q752-E756 WeakPolarHBondContact O-CG 3.26Å; Q752-E756 PolarHBondContact O-N 3.16Å
757L80.1Confident78.8Confident48 Ų4865.9 Ų65.925%0.25136%0.36SS..THydrogen-bonded Turntrans-102.95.6-176-67.1173.9000113.6V724 E725 M728 I753 T754 E755 L759V724-L757 HydrophobicContact CB-CD1 4.37Å; V724-L757 HydrophobicContact CG1-CD1 3.71Å; E725-L757 HydrophobicContact CG-CD1 4.31Å; M728-L757 HydrophobicContact SD-CB 4.09Å; M728-L757 HydrophobicContact SD-CD1 4.08Å; M728-L757 HydrophobicContact SD-CD2 4.36Å; M728-L757 HydrophobicContact SD-CG 4.41Å; I753-L757 HydrophobicContact CG2-CD1 3.95Å; I753-L757 WeakPolarHBondContact O-CB 3.19Å; I753-L757 WeakPolarHBondContact O-CD1 3.46Å; I753-L757 VanDerWaalsContact O-CG 3.24Å; I753-L757 WeakPolarHBondContact O-CG 3.27Å; I753-L757 PolarHBondContact O-N 3.47Å; T754-L757 CarbonylContact O-C 3.59Å; T754-L757 PolarHBondContact O-N 3.14Å; E755-L757 PolarHBondContact O-N 2.68Å; L757-L759 VanDerWaalsContact C-N 3.33Å; L757-L759 HydrophobicContact CB-CD1 4.48Å; L757-L759 HydrophobicContact CB-CG 4.47Å; L757-L759 PolarHBondContact O-N 3.39Å
758G78.8Confident77.5Confident54 Ų5467.1 Ų67.156%0.55739%0.388SS*.THydrogen-bonded Turntrans67.328.1177.200000114.8T754 E755T754-G758 PolarHBondContact O-N 3.07Å; T754-G758 VanDerWaalsContact O-N 3.13Å; E755-G758 PolarHBondContact O-N 2.98Å
759L82.9Confident76.5Confident18 Ų1865.1 Ų65.19%0.09439%0.39CS..  trans-101.1150.1178.9-63.5175.1000111.4V724 F727 M728 T754 L757 V774 R776V724-L759 HydrophobicContact CG1-CD1 3.51Å; F727-L759 HydrophobicContact CD1-CD1 4.33Å; F727-L759 HydrophobicContact CE1-CD1 4.44Å; M728-L759 HydrophobicContact CG-CD1 3.9Å; M728-L759 HydrophobicContact CG-CD2 4.43Å; M728-L759 HydrophobicContact SD-CD1 4.11Å; T754-L759 PolarHBondContact O-N 3.1Å; L757-L759 VanDerWaalsContact C-N 3.33Å; L757-L759 HydrophobicContact CB-CD1 4.48Å; L757-L759 HydrophobicContact CB-CG 4.47Å; L757-L759 PolarHBondContact O-N 3.39Å; L759-V774 HydrophobicContact CB-CG1 3.98Å; L759-V774 HydrophobicContact CD1-CG1 4Å; L759-R776 HydrophobicContact CD2-CG 4.24Å
760V83.8Confident76Confident75 Ų7570 Ų7046%0.45541%0.407SS..EExtended strand (participates in β ladder)trans-82.4132.7177.9-178.40000109.2V774 S775 P777V760-V774 WeakPolarHBondContact O-CA 3.43Å; V760-S775 PolarHBondContact N-O 3Å; V760-S775 PolarHBondContact O-N 2.99Å; V760-P777 HydrophobicContact CG2-CB 4.27Å
761H85.9Confident75.9Confident66 Ų6670.8 Ų70.831%0.30641%0.412SS..EExtended strand (participates in β ladder)trans-124.7135.2179.464.549.2000111.9H751 T754 T773H751-H761 AromaticContact CE1-CE1 3.97Å; H751-H761 AromaticContact CE1-CG 3.95Å; H751-H761 AromaticContact CE1-ND1 3.56Å; H751-H761 AromaticContact ND1-CD2 3.5Å; H751-H761 AromaticContact ND1-CE1 3.22Å; H751-H761 PolarHBondContact ND1-CE1 2.86Å; H751-H761 AromaticContact ND1-CG 3.27Å; H751-H761 VanDerWaalsContact ND1-CG 3.27Å; H751-H761 AromaticContact ND1-ND1 3.08Å; H751-H761 PolarHBondContact ND1-ND1 3.33Å; H751-H761 AromaticContact ND1-NE2 3.42Å; H751-H761 PolarHBondContact ND1-NE2 2.98Å; T754-H761 PolarHBondContact OG1-CD2 3.22Å; H761-T773 WeakPolarHBondContact CA-O 3.38Å
762E81.4Confident76Confident92 Ų9268.8 Ų68.843%0.4340%0.403SS..EExtended strand (participates in β ladder)trans-135.5132.7179-160.7-171.9167.800111.4R764 I772 T773E762-R764 VanDerWaalsContact CD-NE 3.3Å; E762-R764 HydrophobicContact CG-CG 4.18Å; E762-R764 IonicContact OE1-NE 2.75Å; E762-R764 PolarHBondContact OE1-NE 3.47Å; E762-R764 IonicContact OE1-NH2 2.83Å; E762-R764 IonicContact OE2-CZ 3.22Å; E762-R764 IonicContact OE2-NE 3.57Å; E762-R764 PolarHBondContact OE2-NE 3.49Å; E762-R764 IonicContact OE2-NH2 2.74Å; E762-R764 PolarHBondContact OE2-NH2 2.96Å; E762-I772 WeakPolarHBondContact O-CA 3.32Å; E762-T773 PolarHBondContact N-O 3.41Å; E762-T773 PolarHBondContact O-N 3.3Å
763S81.1Confident76.1Confident37 Ų3765.9 Ų65.926%0.25939%0.391SS..EExtended strand (participates in β ladder)trans-87.5108.5169.6-89.40000109.7R770 C771S763-R770 VanDerWaalsContact CB-NH2 3.33Å; S763-R770 PolarHBondContact OG-NE 2.99Å; S763-R770 PolarHBondContact OG-NH2 2.81Å; S763-C771 WeakPolarHBondContact CA-O 3.32Å
764R71.8Confident76.1Confident142 Ų14265.9 Ų65.954%0.53639%0.391SS..EExtended strand (participates in β ladder)trans-106.1139.3178.3-68.5-169.5178.6-164.8-1.9112.6E762 R770 C771E762-R764 VanDerWaalsContact CD-NE 3.3Å; E762-R764 HydrophobicContact CG-CG 4.18Å; E762-R764 IonicContact OE1-NE 2.75Å; E762-R764 PolarHBondContact OE1-NE 3.47Å; E762-R764 IonicContact OE1-NH2 2.83Å; E762-R764 IonicContact OE2-CZ 3.22Å; E762-R764 IonicContact OE2-NE 3.57Å; E762-R764 PolarHBondContact OE2-NE 3.49Å; E762-R764 IonicContact OE2-NH2 2.74Å; E762-R764 PolarHBondContact OE2-NH2 2.96Å; R764-R770 WeakPolarHBondContact O-CA 3.3Å; R764-C771 PolarHBondContact N-O 3.49Å; R764-C771 PolarHBondContact O-N 2.83Å; R764-C771 PolarHBondContact O-SG 3.17Å; R764-C771 VanDerWaalsContact O-SG 3.36Å
765G67.3Low76.3Confident53 Ų5367.5 Ų67.555%0.54640%0.402SS..SBendtrans93.8157175.500000115R770G765-R770 WeakPolarHBondContact O-CB 3.47Å; G765-R770 WeakPolarHBondContact O-CG 3.47Å
766E50.5Low76.2Confident186 Ų18664.5 Ų64.587%0.86939%0.385SS*.SBendtrans-101.7153.8-178.7-63.3-171.2159.700112.7G768 G769E766-G768 PolarHBondContact O-N 2.63Å; E766-G769 PolarHBondContact O-N 3.23Å
767G63.4Low75.6Confident68 Ų6862.9 Ų62.970%0.70138%0.384SS*.G310 helixtrans55.4-135.9175.400000114.3G769 R770G767-G769 PolarHBondContact O-N 2.99Å; G767-R770 WeakPolarHBondContact O-CB 3.4Å; G767-R770 PolarHBondContact O-N 3.13Å
768G54.4Low74.7Confident73 Ų7367.1 Ų67.175%0.75341%0.412SS*.G310 helixtrans-66.7-11.3-178.200000115.3S740 E766S740-G768 WeakPolarHBondContact CB-O 3.42Å; S740-G768 PolarHBondContact OG-O 2.63Å; E766-G768 PolarHBondContact O-N 2.63Å
769G59.4Low72.9Confident51 Ų5168.9 Ų68.953%0.52642%0.421SS..G310 helixtrans-87.4-6.4175.600000114.6E766 G767 C771E766-G769 PolarHBondContact O-N 3.23Å; G767-G769 PolarHBondContact O-N 2.99Å; G769-C771 PolarHBondContact O-N 2.85Å; G769-C771 VanDerWaalsContact O-N 3.11Å
770R72.8Confident70.6Confident116 Ų11673.6 Ų73.644%0.43846%0.455SS..  trans-65.5110.2-171.6-175.3178.3168.1170.60.7112.9S740 R747 S763 R764 G765 G767S740-R770 WeakPolarHBondContact CA-O 3.37Å; S740-R770 VanDerWaalsContact CB-O 3.23Å; S740-R770 WeakPolarHBondContact CB-O 3.27Å; R747-R770 PolarHBondContact NH1-O 3.37Å; R747-R770 PolarHBondContact NH2-O 3.29Å; S763-R770 VanDerWaalsContact CB-NH2 3.33Å; S763-R770 PolarHBondContact OG-NE 2.99Å; S763-R770 PolarHBondContact OG-NH2 2.81Å; R764-R770 WeakPolarHBondContact O-CA 3.3Å; G765-R770 WeakPolarHBondContact O-CB 3.47Å; G765-R770 WeakPolarHBondContact O-CG 3.47Å; G767-R770 WeakPolarHBondContact O-CB 3.4Å; G767-R770 PolarHBondContact O-N 3.13Å
771C81.6Confident68Low17 Ų1778 Ų7812%0.11547%0.471CS..EExtended strand (participates in β ladder)trans-104.5165.7176.162.70000111.3Q737 F738 S763 R764 G769Q737-C771 HydrophobicContact CG-CB 4.22Å; Q737-C771 PolarHBondContact NE2-SG 3.24Å; F738-C771 WeakPolarHBondContact O-CB 3.5Å; S763-C771 WeakPolarHBondContact CA-O 3.32Å; R764-C771 PolarHBondContact N-O 3.49Å; R764-C771 PolarHBondContact O-N 2.83Å; R764-C771 PolarHBondContact O-SG 3.17Å; R764-C771 VanDerWaalsContact O-SG 3.36Å; G769-C771 PolarHBondContact O-N 2.85Å; G769-C771 VanDerWaalsContact O-N 3.11Å
772I84.1Confident65.5Low3 Ų381 Ų812%0.01550%0.496CS..EExtended strand (participates in β ladder)trans-113.9126.6170.3-60.6172.7000107.9Q737 F738 R747 I750 E762 V774Q737-I772 WeakPolarHBondContact CA-O 3.36Å; F738-I772 HydrophobicContact CB-CB 4.45Å; F738-I772 PolarHBondContact N-O 3.08Å; F738-I772 PolarHBondContact O-N 2.99Å; R747-I772 HydrophobicContact CB-CD1 3.86Å; R747-I772 HydrophobicContact CG-CD1 3.84Å; I750-I772 HydrophobicContact CB-CD1 4.44Å; I750-I772 HydrophobicContact CD1-CD1 4.33Å; I750-I772 HydrophobicContact CG2-CD1 4.46Å; I750-I772 HydrophobicContact CG2-CG2 3.87Å; E762-I772 WeakPolarHBondContact O-CA 3.32Å; I772-V774 HydrophobicContact CG2-CG2 4.49Å
773T85.1Confident63Low25 Ų2583.4 Ų83.415%0.15352%0.517CS..EExtended strand (participates in β ladder)trans-108.1134.3174-550000109.1N735 L736 H761 E762N735-T773 HydrophobicContact CB-CG2 3.97Å; L736-T773 CarbonylContact O-C 3.57Å; L736-T773 WeakPolarHBondContact O-CA 3.48Å; H761-T773 WeakPolarHBondContact CA-O 3.38Å; E762-T773 PolarHBondContact N-O 3.41Å; E762-T773 PolarHBondContact O-N 3.3Å
774V86.3Confident60.5Low0 Ų090.2 Ų90.20%055%0.545CS..EExtended strand (participates in β ladder)trans-115.2130.2176.7-176.30000107.9F727 N735 L736 F738 I750 T754 L759 V760 I772F727-V774 HydrophobicContact CE1-CG1 4.32Å; N735-V774 CarbonylContact C-O 3.48Å; N735-V774 WeakPolarHBondContact CA-O 3.26Å; L736-V774 HydrophobicContact CB-CB 4.4Å; L736-V774 PolarHBondContact N-O 3.46Å; L736-V774 PolarHBondContact O-N 3.06Å; F738-V774 HydrophobicContact CD2-CG2 4.19Å; F738-V774 HydrophobicContact CE2-CG2 3.87Å; I750-V774 HydrophobicContact CG2-CG2 4.19Å; T754-V774 HydrophobicContact CG2-CB 4.25Å; T754-V774 HydrophobicContact CG2-CG1 3.47Å; T754-V774 VanDerWaalsContact CG2-CG1 3.47Å; T754-V774 HydrophobicContact CG2-CG2 3.7Å; L759-V774 HydrophobicContact CB-CG1 3.98Å; L759-V774 HydrophobicContact CD1-CG1 4Å; V760-V774 WeakPolarHBondContact O-CA 3.43Å; I772-V774 HydrophobicContact CG2-CG2 4.49Å
775S84.6Confident58.4Low33 Ų3392.2 Ų92.223%0.23156%0.56CS.*EExtended strand (participates in β ladder)trans-133.2158.7-179.761.20000111N735 V760N735-S775 VanDerWaalsContact OD1-CB 3.24Å; N735-S775 WeakPolarHBondContact OD1-CB 3.49Å; V760-S775 PolarHBondContact N-O 3Å; V760-S775 PolarHBondContact O-N 2.99Å
776R81.2Confident56.7Low83 Ų8395.5 Ų95.531%0.31357%0.572SS.*PPolyproline II helixtrans-79.6141.6173-57.9-178.3-173.7-1530.8109.2F727 M728 D730 L759 V778F727-R776 HydrophobicContact CE1-CG 4.01Å; F727-R776 HydrophobicContact CZ-CG 4.09Å; F727-R776 PolarHBondContact O-NH2 3.48Å; M728-R776 VanDerWaalsContact C-NH2 3.28Å; M728-R776 PolarHBondContact O-NH2 3.19Å; D730-R776 PolarHBondContact O-NH2 3.28Å; L759-R776 HydrophobicContact CD2-CG 4.24Å; R776-V778 PolarHBondContact O-N 3.42Å
777P71.8Confident55.4Low80 Ų8093.3 Ų93.352%0.51957%0.571SS.*PPolyproline II helixtrans-60.512917125.7-33000109.6V760V760-P777 HydrophobicContact CG2-CB 4.27Å
778V60Low53.7Low138 Ų13899.1 Ų99.184%0.83658%0.58SS**PPolyproline II helixtrans-80.9127.6176.5-178.90000107.9R776 S780R776-V778 PolarHBondContact O-N 3.42Å; V778-S780 PolarHBondContact O-N 3.26Å
779A41.7Very low52.4Low91 Ų91105 Ų10575%0.75259%0.588SS**PPolyproline II helixtrans-67.4125.2170.100000108.9E781A779-E781 PolarHBondContact O-N 3.24Å
780S34.4Very low50.8Low116 Ų116111.4 Ų111.481%0.81160%0.604SS**  trans-73.9112.7179.651.10000111V778V778-S780 PolarHBondContact O-N 3.26Å
781E29.9Very low48.4Very low169 Ų169111.8 Ų111.879%0.7962%0.62SS**PPolyproline II helixtrans-67150.2155.6-71.9-178.2158.200109.4A779 V783A779-E781 PolarHBondContact O-N 3.24Å; E781-V783 PolarHBondContact O-N 2.95Å
782P32.9Very low45.6Very low127 Ų127118 Ų11883%0.82565%0.647SS**PPolyproline II helixtrans-70.5125.9-179.929.5-33.3000109.9
783V29.1Very low42.8Very low143 Ų143125 Ų12587%0.86768%0.679SS**PPolyproline II helixtrans-97.9129.9175.1177.30000109.3E781E781-V783 PolarHBondContact O-N 2.95Å
784E28.6Very low40Very low181 Ų181131.7 Ų131.785%0.84671%0.709SS**PPolyproline II helixtrans-67.4159.4-177.7-62.2160.513900112.5
785E28Very low37.1Very low184 Ų184139.8 Ų139.886%0.8675%0.747SS**PPolyproline II helixtrans-68.3148.2175.8-64.6-175.714800111.8T787E785-T787 PolarHBondContact O-N 2.84Å
786P31Very low34.1Very low121 Ų121144.1 Ų144.179%0.78677%0.772SS**PPolyproline II helixtrans-75.5120.4-179.330.1-33.4000111.7Q788P786-Q788 PolarHBondContact O-N 3.04Å
787T23.7Very low32Very low140 Ų140144.7 Ų144.786%0.85979%0.787SS**PPolyproline II helixtrans-55.2126.7166.443.40000111.6E785E785-T787 PolarHBondContact O-N 2.84Å
788Q28Very low29.8Very low190 Ų190149 Ų14989%0.88880%0.8SS**PPolyproline II helixtrans-89.5143.3161.1-67.5-176.9-8.700109.4P786P786-Q788 PolarHBondContact O-N 3.04Å
789E26.6Very low28.2Very low198 Ų198150 Ų15093%0.92580%0.796SS**PPolyproline II helixtrans-74.7156.1177.1-69.4179.8148.900111.9
790E25.1Very low27.5Very low184 Ų184154.1 Ų154.186%0.8680%0.799SS**PPolyproline II helixtrans-70.7147.8-164-54.5167.8147.700114.2
791T23.1Very low26.8Very low124 Ų124154.9 Ų154.976%0.76180%0.799SS**  trans-164110130.83.40000113.7
792Q23.2Very low27Very low149 Ų149151.6 Ų151.670%0.69679%0.792SS**  trans57.3124.5138-68.7178.7-70.600123.6
793E25.1Very low26.6Very low148 Ų148154.3 Ų154.369%0.69279%0.794SS**  94.5117.8129.1-73.7160.8-155.900122.9
794E25.8Very low26.4Very low167 Ų167157 Ų15778%0.7880%0.797SS**  trans78.4107.3139.1-63.2-176.3169.100124.3
795E26.2Very low26.3Very low169 Ų169157 Ų15779%0.7980%0.797SS**  58.1106.1124.1-60-166168.400123.9
796T20.3Very low26.2Very low125 Ų125154.5 Ų154.577%0.76780%0.797SS**  35.2162.8119.942.30000124.2
797P38.3Very low25.9Very low94 Ų94152.9 Ų152.961%0.6179%0.794SS**  cis-139.8-166.8-16.935.8-13.6000115.7
798E25Very low26.3Very low170 Ų170152 Ų15279%0.79479%0.79SS**  trans73147.1156.6-76.3147.3-148.900118.1
799E26.3Very low26.1Very low161 Ų161147.9 Ų147.975%0.75279%0.789SS**  cis-156.8147.732.1-142.7166.1-144.700113.7
800E26Very low26.1Very low177 Ų177146.6 Ų146.683%0.82779%0.787SS**  trans58.1147.6148-72.4179.9-179.500128
801T20.6Very low26.1Very low131 Ų131147.3 Ų147.380%0.80479%0.791SS**  trans-108.8-167-178.451.60000110.2
802P35.2Very low26.3Very low100 Ų100146.8 Ų146.865%0.64979%0.792SS**  cis-144.6169.47.643.8-22.7000120.3
803E23.9Very low26.4Very low184 Ų184148.2 Ų148.286%0.8680%0.799SS**  trans43.2129.1137.2-63.5170.1-177.600124.1
804E25.6Very low26.7Very low199 Ų199146.9 Ų146.993%0.9380%0.803SS**  -161.5161.2107.2-109.8-177.3-178.800112.1
805E25Very low27Very low182 Ų182144.5 Ų144.585%0.8580%0.802SS**  trans-80.2170.2-162.4-43.1-176.6130.100115.9
806P26.4Very low27.2Very low131 Ų131142.1 Ų142.185%0.85180%0.801SS**  -148.1159.88238.4-20.2000117.4
807A24.6Very low27.9Very low87 Ų87141.9 Ų141.972%0.71981%0.805SS**  trans-126.2172.3162.100000109.8
808P31.3Very low27.5Very low121 Ų121146.1 Ų146.179%0.78682%0.816SS**  cis-124.9159.3-4.239.3-25000114.4
809A25Very low28Very low105 Ų105143.3 Ų143.387%0.86881%0.813SS**PPolyproline II helixtrans-84127170.700000111.9
810L26Very low28.4Very low170 Ų170141.5 Ų141.589%0.8982%0.818SS**PPolyproline II helixtrans-90140.7165.9-93.5159.3000110.5
811Q25.6Very low29.2Very low199 Ų199137.4 Ų137.493%0.9381%0.805SS**PPolyproline II helixtrans-70.8134.1-175.5-64.4166.6-12.900111.7
812S26.4Very low30.4Very low113 Ų113135.4 Ų135.479%0.7979%0.79SS**  trans-135.4131.1162.662.60000109.8
813E26.9Very low30.7Very low180 Ų180137.3 Ų137.384%0.84179%0.793SS**PPolyproline II helixtrans-60.6151.6-175.5-59.8178.4141.800113.2
814P31Very low31.7Very low119 Ų119136 Ų13677%0.77379%0.785SS**PPolyproline II helixtrans-67.1137.5172.828.8-34.2000110.8
815P31.7Very low32.7Very low118 Ų118130.2 Ų130.277%0.76676%0.763SS**PPolyproline II helixtrans-68.6147.6-179.628.6-34.8000111.5
816P31.2Very low33.8Very low118 Ų118126 Ų12677%0.76675%0.746SS**PPolyproline II helixtrans-66.5138.2-179.427.5-34.5000111.6Q818P816-Q818 PolarHBondContact O-N 3.36Å
817S33.1Very low35.2Very low121 Ų121125.4 Ų125.485%0.84673%0.732SS**PPolyproline II helixtrans-58.8117.1174.144.80000110.9
818Q31.5Very low36.3Very low182 Ų182125.6 Ų125.685%0.8572%0.72SS**PPolyproline II helixtrans-68.9139.4174.1-67.8-173.2-5.100110.1P816P816-Q818 PolarHBondContact O-N 3.36Å
819P34.1Very low37.4Very low111 Ų111124.5 Ų124.572%0.72170%0.704SS**PPolyproline II helixtrans-67.8150.3178.729.1-34.8000111V821P819-V821 PolarHBondContact O-N 3.25Å
820S36Very low38.7Very low123 Ų123127.9 Ų127.986%0.8670%0.695SS**PPolyproline II helixtrans-57.6123.4175.2450000110.9D822S820-D822 PolarHBondContact O-N 2.92Å
821V41.8Very low39.9Very low92 Ų92124.5 Ų124.556%0.55868%0.676SS**  trans-74.3110.5-172.8179.60000109.9P819 L823 L826P819-V821 PolarHBondContact O-N 3.25Å; V821-L823 PolarHBondContact O-N 3.31Å; V821-L826 HydrophobicContact CG1-CD1 3.33Å; V821-L826 HydrophobicContact CG1-CG 4.34Å
822D47Very low41.3Very low89 Ų89122.3 Ų122.348%0.47666%0.659SS.*  trans-69.1101.4171.8177.517.7000110.2S820 K824 T825 L826S820-D822 PolarHBondContact O-N 2.92Å; D822-K824 PolarHBondContact O-N 3.47Å; D822-K824 WeakPolarHBondContact OD1-CB 3.26Å; D822-K824 PolarHBondContact OD1-N 3.06Å; D822-T825 WeakPolarHBondContact CB-OG1 3.46Å; D822-T825 PolarHBondContact O-N 2.99Å; D822-T825 VanDerWaalsContact O-N 3.14Å; D822-T825 PolarHBondContact O-OG1 3.25Å; D822-T825 PolarHBondContact OD2-OG1 2.96Å; D822-L826 PolarHBondContact O-N 3.45Å
823L40.1Very low42.8Very low139 Ų139125.1 Ų125.173%0.72865%0.652SS**Hα-helixtrans-56.5-23.4179-64.8169.4000112.8V821 H827V821-L823 PolarHBondContact O-N 3.31Å; L823-H827 VanDerWaalsContact O-CB 3.26Å; L823-H827 WeakPolarHBondContact O-CB 3.47Å; L823-H827 PolarHBondContact O-N 3.33Å
824K45.2Very low44.1Very low156 Ų156120.7 Ų120.768%0.67863%0.632SS**Hα-helixtrans-73.2-38.8178.4-65.4174.2-179.1166.90112.3D822 H827 L828D822-K824 PolarHBondContact O-N 3.47Å; D822-K824 WeakPolarHBondContact OD1-CB 3.26Å; D822-K824 PolarHBondContact OD1-N 3.06Å; K824-H827 PolarHBondContact O-N 3.5Å; K824-L828 WeakPolarHBondContact O-CB 3.26Å; K824-L828 PolarHBondContact O-N 2.9Å
825T47.1Very low45.3Very low79 Ų79120.6 Ų120.649%0.48562%0.621SS.*Hα-helixtrans-68.4-44.7178.170000111D822 H827 L828 E829D822-T825 WeakPolarHBondContact CB-OG1 3.46Å; D822-T825 PolarHBondContact O-N 2.99Å; D822-T825 VanDerWaalsContact O-N 3.14Å; D822-T825 PolarHBondContact O-OG1 3.25Å; D822-T825 PolarHBondContact OD2-OG1 2.96Å; T825-H827 VanDerWaalsContact C-N 3.34Å; T825-H827 PolarHBondContact O-N 3.43Å; T825-L828 PolarHBondContact O-N 3.36Å; T825-E829 PolarHBondContact O-N 3.14Å
826L48Very low46.6Very low93 Ų93120.5 Ų120.549%0.48761%0.61SS.*Hα-helixtrans-62.7-38.1174.1-79.1174.7000112.8V821 D822 E829 R830V821-L826 HydrophobicContact CG1-CD1 3.33Å; V821-L826 HydrophobicContact CG1-CG 4.34Å; D822-L826 PolarHBondContact O-N 3.45Å; L826-E829 PolarHBondContact O-N 3.36Å; L826-R830 WeakPolarHBondContact O-CB 3.25Å; L826-R830 PolarHBondContact O-N 2.93Å
827H54.8Low48Very low119 Ų119121.6 Ų121.655%0.55160%0.603SS**Hα-helixtrans-63-42.7173.7178.678.1000112.1L823 K824 T825 R830 M831L823-H827 VanDerWaalsContact O-CB 3.26Å; L823-H827 WeakPolarHBondContact O-CB 3.47Å; L823-H827 PolarHBondContact O-N 3.33Å; K824-H827 PolarHBondContact O-N 3.5Å; T825-H827 VanDerWaalsContact C-N 3.34Å; T825-H827 PolarHBondContact O-N 3.43Å; H827-R830 PolarHBondContact O-N 3.15Å; H827-M831 WeakPolarHBondContact O-CB 3.46Å; H827-M831 WeakPolarHBondContact O-CG 3.38Å; H827-M831 PolarHBondContact O-N 2.98Å
828L49Very low49Very low90 Ų90124.3 Ų124.347%0.47159%0.594SS.*Hα-helixtrans-64.4-36.4175-89.4154.3000112.9K824 T825 R832K824-L828 WeakPolarHBondContact O-CB 3.26Å; K824-L828 PolarHBondContact O-N 2.9Å; T825-L828 PolarHBondContact O-N 3.36Å; L828-R832 VanDerWaalsContact O-CG 3.29Å; L828-R832 WeakPolarHBondContact O-CG 3.33Å; L828-R832 PolarHBondContact O-N 3.08Å; L828-R832 VanDerWaalsContact O-N 3.15Å
829E53.5Low50.3Low98 Ų98120.8 Ų120.846%0.45858%0.578SS.*Hα-helixtrans-70.2-41172.9-71.1-164.1145.400112.8T825 L826 R832 R833T825-E829 PolarHBondContact O-N 3.14Å; L826-E829 PolarHBondContact O-N 3.36Å; E829-R832 PolarHBondContact O-N 3.17Å; E829-R833 WeakPolarHBondContact O-CG 2.97Å; E829-R833 PolarHBondContact O-N 3.2Å
830R52.6Low51.4Low176 Ų176120.8 Ų120.866%0.66457%0.568SS**Hα-helixtrans-62.1-45.4175.8-172.2173.2177.7165.70.9111.3L826 H827 R832 R833 E834L826-R830 WeakPolarHBondContact O-CB 3.25Å; L826-R830 PolarHBondContact O-N 2.93Å; H827-R830 PolarHBondContact O-N 3.15Å; R830-R832 VanDerWaalsContact C-N 3.35Å; R830-R832 PolarHBondContact O-N 3.27Å; R830-R833 PolarHBondContact O-N 3.33Å; R830-E834 PolarHBondContact O-N 2.9Å
831M52.5Low52.2Low99 Ų99119.3 Ų119.349%0.48855%0.551SS.*Hα-helixtrans-58-43.3173.8-82-72.7-73.500112.4H827 E834 Q835H827-M831 WeakPolarHBondContact O-CB 3.46Å; H827-M831 WeakPolarHBondContact O-CG 3.38Å; H827-M831 PolarHBondContact O-N 2.98Å; M831-E834 PolarHBondContact O-N 3.16Å; M831-Q835 WeakPolarHBondContact O-CB 3.35Å; M831-Q835 PolarHBondContact O-N 3.32Å
832R53.5Low53.1Low153 Ų153118.8 Ų118.858%0.57755%0.547SS*.Hα-helixtrans-64.1-41.2176.3-75.3169.8179.91590.5112.6L828 E829 R830 Q835 Q836L828-R832 VanDerWaalsContact O-CG 3.29Å; L828-R832 WeakPolarHBondContact O-CG 3.33Å; L828-R832 PolarHBondContact O-N 3.08Å; L828-R832 VanDerWaalsContact O-N 3.15Å; E829-R832 PolarHBondContact O-N 3.17Å; R830-R832 VanDerWaalsContact C-N 3.35Å; R830-R832 PolarHBondContact O-N 3.27Å; R832-Q835 PolarHBondContact O-N 2.88Å; R832-Q836 WeakPolarHBondContact O-CG 3.42Å; R832-Q836 PolarHBondContact O-N 2.99Å
833R58.9Low53.2Low172 Ų172120.4 Ų120.465%0.64955%0.552SS**Hα-helixtrans-65.4-38.1176.5-72.7178.6-179.5175.64112.5E829 R830 K837E829-R833 WeakPolarHBondContact O-CG 2.97Å; E829-R833 PolarHBondContact O-N 3.2Å; R830-R833 PolarHBondContact O-N 3.33Å; R833-K837 PolarHBondContact O-N 2.91Å
834E54.4Low53.6Low88 Ų88119.5 Ų119.541%0.41154%0.544SS..Hα-helixtrans-68.6-36.5173.2-75-169.6-177.100112.6R830 M831 K837 R838R830-E834 PolarHBondContact O-N 2.9Å; M831-E834 PolarHBondContact O-N 3.16Å; E834-K837 PolarHBondContact O-N 3.31Å; E834-R838 WeakPolarHBondContact O-CG 3.47Å; E834-R838 PolarHBondContact O-N 3.3Å
835Q54.5Low53.7Low116 Ų116119.8 Ų119.854%0.54255%0.545SS..Hα-helixtrans-65.3-43.7176.4-159.8164.58.300111.2M831 R832 R838 E839M831-Q835 WeakPolarHBondContact O-CB 3.35Å; M831-Q835 PolarHBondContact O-N 3.32Å; R832-Q835 PolarHBondContact O-N 2.88Å; Q835-R838 PolarHBondContact O-N 3.16Å; Q835-E839 WeakPolarHBondContact O-CG 3.5Å; Q835-E839 PolarHBondContact O-N 2.88Å
836Q59.4Low53.5Low116 Ų116123.4 Ų123.454%0.54256%0.555SS.*Hα-helixtrans-60.7-47.9172.1-74.2175.5-35.400112.3R832 R838 E839 E840R832-Q836 WeakPolarHBondContact O-CG 3.42Å; R832-Q836 PolarHBondContact O-N 2.99Å; Q836-R838 PolarHBondContact O-N 3.1Å; Q836-E839 PolarHBondContact O-N 2.96Å; Q836-E840 WeakPolarHBondContact O-CG 3.3Å; Q836-E840 PolarHBondContact O-N 2.98Å
837K60.7Low53.1Low142 Ų142126.4 Ų126.462%0.61757%0.566SS**Hα-helixtrans-59.4-32.3174.8-86-174172-177.90113.4R833 E834 N841R833-K837 PolarHBondContact O-N 2.91Å; E834-K837 PolarHBondContact O-N 3.31Å; K837-N841 WeakPolarHBondContact O-CB 3.25Å; K837-N841 PolarHBondContact O-N 2.87Å; K837-N841 PolarHBondContact O-ND2 3.22Å
838R54.7Low52.5Low177 Ų177128.5 Ų128.567%0.66858%0.576SS**Hα-helixtrans-71.4-38.9174-76.2177.8179.3-174.83111.7E834 Q835 Q836 V842E834-R838 WeakPolarHBondContact O-CG 3.47Å; E834-R838 PolarHBondContact O-N 3.3Å; Q835-R838 PolarHBondContact O-N 3.16Å; Q836-R838 PolarHBondContact O-N 3.1Å; R838-V842 VanDerWaalsContact O-CG2 3.31Å; R838-V842 WeakPolarHBondContact O-CG2 3.48Å; R838-V842 PolarHBondContact O-N 2.93Å; R838-V842 VanDerWaalsContact O-N 3.08Å
839E58.7Low52.1Low108 Ų108131 Ų13151%0.50559%0.59SS.*Hα-helixtrans-67.5-42.4176.3-72.3175-178.100112.2Q835 Q836 V842 Q843Q835-E839 WeakPolarHBondContact O-CG 3.5Å; Q835-E839 PolarHBondContact O-N 2.88Å; Q836-E839 PolarHBondContact O-N 2.96Å; E839-V842 PolarHBondContact O-N 3.42Å; E839-Q843 WeakPolarHBondContact O-CG 3.39Å; E839-Q843 PolarHBondContact O-N 3.44Å
840E56.6Low50.9Low112 Ų112131.7 Ų131.752%0.52360%0.604SS.*Hα-helixtrans-60-46.1173.7-71.4173.4164.200111.9Q836 V842 Q843 Q844Q836-E840 WeakPolarHBondContact O-CG 3.3Å; Q836-E840 PolarHBondContact O-N 2.98Å; E840-V842 VanDerWaalsContact C-N 3.28Å; E840-V842 PolarHBondContact O-N 3.2Å; E840-Q843 PolarHBondContact O-N 2.83Å; E840-Q843 VanDerWaalsContact O-N 3.12Å; E840-Q844 WeakPolarHBondContact O-CG 3.48Å; E840-Q844 PolarHBondContact O-N 3.46Å
841N53.4Low50.1Low92 Ų92130.8 Ų130.849%0.49261%0.613SS.*Hα-helixtrans-62.7-32.1175.2-84.7-60.5000113.1K837 K845K837-N841 WeakPolarHBondContact O-CB 3.25Å; K837-N841 PolarHBondContact O-N 2.87Å; K837-N841 PolarHBondContact O-ND2 3.22Å; N841-K845 WeakPolarHBondContact O-CG 3.41Å; N841-K845 PolarHBondContact O-N 3.42Å; N841-K845 VanDerWaalsContact O-N 3.14Å
842V60.2Low50.1Low80 Ų80131.8 Ų131.849%0.48563%0.627SS.*Hα-helixtrans-73.6-33.4174168.40000111.6R838 E839 E840 K846R838-V842 VanDerWaalsContact O-CG2 3.31Å; R838-V842 WeakPolarHBondContact O-CG2 3.48Å; R838-V842 PolarHBondContact O-N 2.93Å; R838-V842 VanDerWaalsContact O-N 3.08Å; E839-V842 PolarHBondContact O-N 3.42Å; E840-V842 VanDerWaalsContact C-N 3.28Å; E840-V842 PolarHBondContact O-N 3.2Å; V842-K846 WeakPolarHBondContact O-CG 3.26Å; V842-K846 PolarHBondContact O-N 3.06Å
843Q50.1Low48.8Very low123 Ų123129.4 Ų129.458%0.57564%0.64SS**Hα-helixtrans-70.5-42.8174-69.9-178.519.200112E839 E840 K845 K846 Q847E839-Q843 WeakPolarHBondContact O-CG 3.39Å; E839-Q843 PolarHBondContact O-N 3.44Å; E840-Q843 PolarHBondContact O-N 2.83Å; E840-Q843 VanDerWaalsContact O-N 3.12Å; Q843-K845 PolarHBondContact O-N 2.78Å; Q843-K846 WeakPolarHBondContact O-CB 3.45Å; Q843-K846 PolarHBondContact O-N 2.98Å; Q843-Q847 PolarHBondContact O-N 2.91Å; Q843-Q847 VanDerWaalsContact O-N 3.1Å
844Q48.4Very low47.3Very low120 Ų120125.5 Ų125.556%0.56164%0.644SS**Hα-helixtrans-60.9-42.2174.5-71.2-179.21.800112E840 K846 Q847 Q848E840-Q844 WeakPolarHBondContact O-CG 3.48Å; E840-Q844 PolarHBondContact O-N 3.46Å; Q844-K846 VanDerWaalsContact C-N 3.26Å; Q844-K846 PolarHBondContact O-N 3.3Å; Q844-Q847 PolarHBondContact O-N 3.14Å; Q844-Q847 VanDerWaalsContact O-N 3.15Å; Q844-Q848 PolarHBondContact O-N 2.82Å
845K47.8Very low46.1Very low162 Ų162130.8 Ų130.870%0.70467%0.669SS**Hα-helixtrans-64.1-25.6173.2-79.2-176.4174.9-178.30114.2N841 Q843N841-K845 WeakPolarHBondContact O-CG 3.41Å; N841-K845 PolarHBondContact O-N 3.42Å; N841-K845 VanDerWaalsContact O-N 3.14Å; Q843-K845 PolarHBondContact O-N 2.78Å
846K41.5Very low44.7Very low156 Ų156128.7 Ų128.768%0.67868%0.679SS**Hα-helixtrans-78.4-27.8173.3-77.8175.9177.1178.40112.9V842 Q843 Q844V842-K846 WeakPolarHBondContact O-CG 3.26Å; V842-K846 PolarHBondContact O-N 3.06Å; Q843-K846 WeakPolarHBondContact O-CB 3.45Å; Q843-K846 PolarHBondContact O-N 2.98Å; Q844-K846 VanDerWaalsContact C-N 3.26Å; Q844-K846 PolarHBondContact O-N 3.3Å
847Q40.9Very low43.2Very low155 Ų155130.4 Ų130.472%0.72470%0.697SS**Hα-helixtrans-78.7-22.2178-71.9177.1-8.100113.5Q843 Q844 N849Q843-Q847 PolarHBondContact O-N 2.91Å; Q843-Q847 VanDerWaalsContact O-N 3.1Å; Q844-Q847 PolarHBondContact O-N 3.14Å; Q844-Q847 VanDerWaalsContact O-N 3.15Å; Q847-N849 VanDerWaalsContact C-N 3.35Å
848Q41.7Very low41.7Very low164 Ų164133.2 Ų133.277%0.76671%0.709SS**THydrogen-bonded Turntrans-78.9-9.4176.1-77.3-175.9-2300115.1Q844Q844-Q848 PolarHBondContact O-N 2.82Å
849N40Very low40.5Very low143 Ų143134.7 Ų134.777%0.76572%0.721SS**  trans-114.379.7179.4-97-7.5000112Q847Q847-N849 VanDerWaalsContact C-N 3.35Å
850C29.3Very low38.9Very low112 Ų112135.6 Ų135.676%0.75774%0.739SS**  trans-145.7145.4164.8-87.90000111.6
851N34.2Very low37.6Very low157 Ų157140.3 Ų140.384%0.8476%0.757SS**  trans91144.5164.9-781.5000120.3
852P53Low36.4Very low120 Ų120139.3 Ų139.378%0.77977%0.769SS**  -146.5167.1-112.142.2-23000118.5
853A26.1Very low34.7Very low103 Ų103145.5 Ų145.585%0.85179%0.789SS**  trans-178.7158.5155.500000111
854A27.7Very low34.2Very low89 Ų89149.7 Ų149.774%0.73681%0.806SS**  cis-163.6138.2-28.700000111.3
855Q29.2Very low33.3Very low199 Ų199153.9 Ų153.993%0.9382%0.822SS**  trans55.7130.1149.5-60.8-175.84.200124.6
856G26Very low32.6Very low73 Ų73152.7 Ų152.775%0.75383%0.829SS**  trans107.6135.6153.400000115.5
857T27.4Very low32.5Very low151 Ų151154.4 Ų154.493%0.92684%0.836SS**  cis-149.8-178.90.231.30000111.6
858K27.8Very low32.8Very low202 Ų202149.3 Ų149.388%0.87882%0.821SS**  trans-80.4138.8-164.5-68.1169.6178.6167.80116.1
859K30.4Very low33.2Very low208 Ų208141.7 Ų141.790%0.90479%0.786SS**  trans36.7128.2141-69-180176.3173.90120.6
860S25Very low33.8Very low126 Ų126136 Ų13688%0.88176%0.758SS**  -142.1155.1128.776.80000111.6
861K29.9Very low34.8Very low212 Ų212134.8 Ų134.892%0.92275%0.751SS**  trans-102128.3-177.6-87.6-177.4173.7179.20111.3
862G27.1Very low35.6Very low71 Ų71131.8 Ų131.873%0.73273%0.734SS**  trans95.3125.2131.700000119.4
863K26Very low35.8Very low209 Ų209128.4 Ų128.491%0.90971%0.709SS**  -168.5145121.6-105.7167.8-177.9175.10110.3
864K38.1Very low37.2Very low212 Ų212126.9 Ų126.992%0.92270%0.697SS**  trans-61.9134.1169.7-71.5174.9174.8175.20109.2
865K30.4Very low38.4Very low207 Ų207126.8 Ų126.890%0.970%0.696SS**  trans-126.7149.2159.5-83.9-170.8174.9-178.10110.4
866T33.8Very low39.6Very low138 Ų138120.9 Ų120.985%0.84768%0.681SS**  trans-77.8147.4-166.736.10000113.3A868T866-A868 PolarHBondContact O-N 3.13Å
867K38.6Very low40.9Very low191 Ų191119.7 Ų119.783%0.8366%0.664SS**  trans-74.2109.2172.4-71.3-173.6176.4-175.50110.5K903K867-K903 PolarHBondContact O-NZ 3.4Å
868A46.9Very low42.2Very low49 Ų49116.9 Ų116.941%0.40565%0.647SS.*  trans-85.8169.9175.200000112T866 D872T866-A868 PolarHBondContact O-N 3.13Å; A868-D872 HydrophobicContact CB-CB 3.53Å
869G50.3Low43.4Very low4 Ų4112.9 Ų112.94%0.04164%0.641CS.*  trans-89.5172.5177.900000113.3C871 D872 I873G869-C871 PolarHBondContact O-N 3.5Å; G869-D872 PolarHBondContact N-OD2 3Å; G869-D872 WeakPolarHBondContact O-CA 3.33Å; G869-D872 WeakPolarHBondContact O-CB 3.36Å; G869-D872 PolarHBondContact O-N 3.34Å; G869-I873 WeakPolarHBondContact O-CG1 3.5Å; G869-I873 PolarHBondContact O-N 2.9Å
870A53.7Low44.4Very low22 Ų22110.3 Ų110.318%0.18264%0.637CS.*Hα-helixtrans-56-41.7-17400000114.3D872 I873 A874A870-D872 VanDerWaalsContact C-N 3.33Å; A870-D872 PolarHBondContact O-N 2.96Å; A870-I873 PolarHBondContact O-N 3.41Å; A870-A874 PolarHBondContact O-N 2.9Å; A870-A874 VanDerWaalsContact O-N 3.15Å
871C48.4Very low45.6Very low88 Ų88109.2 Ų109.260%0.59562%0.622SS**Hα-helixtrans-65.1-35174.5-660000113.1G869 I873 A875G869-C871 PolarHBondContact O-N 3.5Å; C871-I873 VanDerWaalsContact C-N 3.32Å; C871-A875 WeakPolarHBondContact O-CB 3.39Å; C871-A875 PolarHBondContact O-N 3.13Å
872D52Low47.2Very low93 Ų93105 Ų10550%0.49761%0.61SS.*Hα-helixtrans-72.3-29.8179.3-47.3-37.3000111.1A868 G869 A870 A876A868-D872 HydrophobicContact CB-CB 3.53Å; G869-D872 PolarHBondContact N-OD2 3Å; G869-D872 WeakPolarHBondContact O-CA 3.33Å; G869-D872 WeakPolarHBondContact O-CB 3.36Å; G869-D872 PolarHBondContact O-N 3.34Å; A870-D872 VanDerWaalsContact C-N 3.33Å; A870-D872 PolarHBondContact O-N 2.96Å; D872-A876 VanDerWaalsContact O-CB 3.32Å; D872-A876 WeakPolarHBondContact O-CB 3.46Å; D872-A876 PolarHBondContact O-N 3.14Å
873I57.8Low48.7Very low49 Ų49109.1 Ų109.125%0.25161%0.608SS.*Hα-helixtrans-71.1-43.9176.1-66.1165.6000110.2G869 A870 C871 A876G869-I873 WeakPolarHBondContact O-CG1 3.5Å; G869-I873 PolarHBondContact O-N 2.9Å; A870-I873 PolarHBondContact O-N 3.41Å; C871-I873 VanDerWaalsContact C-N 3.32Å; I873-A876 PolarHBondContact O-N 3.43Å
874A53.7Low50.6Low71 Ų71104.6 Ų104.659%0.58759%0.593SS**Hα-helixtrans-67.7-36.2176.800000112.9A870 A876A870-A874 PolarHBondContact O-N 2.9Å; A870-A874 VanDerWaalsContact O-N 3.15Å; A874-A876 VanDerWaalsContact C-N 3.27Å; A874-A876 PolarHBondContact O-N 3.16Å
875A54.4Low51.7Low88 Ų8896.9 Ų96.973%0.72757%0.569SS**THydrogen-bonded Turntrans-76.8-9178.400000114.4C871C871-A875 WeakPolarHBondContact O-CB 3.39Å; C871-A875 PolarHBondContact O-N 3.13Å
876A54.2Low53.3Low74 Ų7490.6 Ų90.661%0.61255%0.545SS*.THydrogen-bonded Turntrans-95.4-4.6-178.800000114.2D872 I873 A874D872-A876 VanDerWaalsContact O-CB 3.32Å; D872-A876 WeakPolarHBondContact O-CB 3.46Å; D872-A876 PolarHBondContact O-N 3.14Å; I873-A876 PolarHBondContact O-N 3.43Å; A874-A876 VanDerWaalsContact C-N 3.27Å; A874-A876 PolarHBondContact O-N 3.16Å
877A53.6Low54.8Low49 Ų4988 Ų8841%0.40553%0.525SS..  trans-87.8116.2175.100000110.2
878V55.2Low55.9Low91 Ų9181.8 Ų81.855%0.55251%0.505SS*.  trans-87.1141.4171.1-178.30000107.4D880 D881V878-D880 PolarHBondContact O-N 2.91Å; V878-D881 PolarHBondContact O-N 3.35Å
879P51.2Low56.8Low118 Ų11880.9 Ų80.977%0.76650%0.498SS*.THydrogen-bonded Turntrans-66.4-2.6-16823.2-35.3000117.6
880D52.3Low57.7Low154 Ų15484.6 Ų84.682%0.82452%0.52SS*.THydrogen-bonded Turntrans-100.88.3-177.8-65.9-40.9000114.2V878V878-D880 PolarHBondContact O-N 2.91Å
881D49.9Very low58.5Low104 Ų10488 Ų8856%0.55654%0.538SS*.SBendtrans-84.5148.9179-84.1-34.3000113.8V878V878-D881 PolarHBondContact O-N 3.35Å
882D62.9Low59.4Low124 Ų12489.9 Ų89.966%0.66354%0.536SS*.  trans-52145.3-173.8-157.4-8.7000114.5D884 A885 L886D882-D884 VanDerWaalsContact C-N 3.33Å; D882-D884 PolarHBondContact O-N 2.93Å; D882-A885 HydrophobicContact CB-CB 4.43Å; D882-A885 WeakPolarHBondContact O-CA 3.38Å; D882-A885 VanDerWaalsContact O-CB 3.26Å; D882-A885 WeakPolarHBondContact O-CB 3.48Å; D882-A885 PolarHBondContact O-N 2.94Å; D882-L886 PolarHBondContact O-N 3.5Å; D882-L886 VanDerWaalsContact O-N 3.08Å
883F59.9Low60.1Low157 Ų15786.6 Ų86.669%0.68952%0.522SS*.Hα-helixtrans-61.5-39-166.8-160-98.4000112.6A885 L886 I887F883-A885 VanDerWaalsContact C-N 3.32Å; F883-A885 PolarHBondContact O-N 2.87Å; F883-L886 WeakPolarHBondContact O-CB 3.45Å; F883-L886 PolarHBondContact O-N 2.97Å; F883-I887 HydrophobicContact CD1-CD1 3.74Å; F883-I887 HydrophobicContact CD1-CG1 4.44Å; F883-I887 HydrophobicContact CE1-CD1 3.84Å; F883-I887 WeakPolarHBondContact O-CG1 3.28Å; F883-I887 PolarHBondContact O-N 3.02Å
884D64.7Low60.7Low114 Ų11489.4 Ų89.461%0.6154%0.538SS*.Hα-helixtrans-69.7-26.6175.4-77.4-23.4000113.2D882 S888D882-D884 VanDerWaalsContact C-N 3.33Å; D882-D884 PolarHBondContact O-N 2.93Å; D884-S888 VanDerWaalsContact O-CB 3.24Å; D884-S888 WeakPolarHBondContact O-CB 3.43Å; D884-S888 PolarHBondContact O-N 3.46Å; D884-S888 PolarHBondContact O-OG 3.37Å
885A61Low61.8Low50 Ų5087.2 Ų87.241%0.41352%0.518SS..Hα-helixtrans-71.8-38.9172.800000110.8D882 F883 S888 A889D882-A885 HydrophobicContact CB-CB 4.43Å; D882-A885 WeakPolarHBondContact O-CA 3.38Å; D882-A885 VanDerWaalsContact O-CB 3.26Å; D882-A885 WeakPolarHBondContact O-CB 3.48Å; D882-A885 PolarHBondContact O-N 2.94Å; F883-A885 VanDerWaalsContact C-N 3.32Å; F883-A885 PolarHBondContact O-N 2.87Å; A885-S888 PolarHBondContact O-N 3.28Å; A885-A889 WeakPolarHBondContact O-CB 3.48Å; A885-A889 PolarHBondContact O-N 3.46Å
886L65.8Low63.1Low75 Ų7584.2 Ų84.239%0.39349%0.49SS..Hα-helixtrans-61.5-49.2173-12886.4000111.5D882 F883 S888 A889 V890D882-L886 PolarHBondContact O-N 3.5Å; D882-L886 VanDerWaalsContact O-N 3.08Å; F883-L886 WeakPolarHBondContact O-CB 3.45Å; F883-L886 PolarHBondContact O-N 2.97Å; L886-S888 VanDerWaalsContact C-N 3.3Å; L886-S888 PolarHBondContact O-N 3.27Å; L886-A889 WeakPolarHBondContact O-CB 3.46Å; L886-A889 PolarHBondContact O-N 2.98Å; L886-A889 VanDerWaalsContact O-N 3.08Å; L886-V890 WeakPolarHBondContact O-CG2 3.38Å; L886-V890 PolarHBondContact O-N 3.45Å
887I63.7Low64.5Low82 Ų8280.7 Ų80.742%0.42146%0.461SS..Hα-helixtrans-57.8-45.6175.4-66.9168.2000110.2F883 A889 V890 V891F883-I887 HydrophobicContact CD1-CD1 3.74Å; F883-I887 HydrophobicContact CD1-CG1 4.44Å; F883-I887 HydrophobicContact CE1-CD1 3.84Å; F883-I887 WeakPolarHBondContact O-CG1 3.28Å; F883-I887 PolarHBondContact O-N 3.02Å; I887-A889 VanDerWaalsContact C-N 3.26Å; I887-A889 PolarHBondContact O-N 3.14Å; I887-V890 PolarHBondContact O-N 3.09Å; I887-V891 HydrophobicContact CG2-CG2 4.31Å; I887-V891 WeakPolarHBondContact O-CG2 3.39Å; I887-V891 PolarHBondContact O-N 3.15Å
888S62.8Low65.9Low61 Ų6180.2 Ų80.243%0.42746%0.455SS..Hα-helixtrans-63.4-28.1177.2-66.30000113.9D884 A885 L886 K892D884-S888 VanDerWaalsContact O-CB 3.24Å; D884-S888 WeakPolarHBondContact O-CB 3.43Å; D884-S888 PolarHBondContact O-N 3.46Å; D884-S888 PolarHBondContact O-OG 3.37Å; A885-S888 PolarHBondContact O-N 3.28Å; L886-S888 VanDerWaalsContact C-N 3.3Å; L886-S888 PolarHBondContact O-N 3.27Å; S888-K892 WeakPolarHBondContact O-CB 3.31Å; S888-K892 WeakPolarHBondContact O-CD 3.36Å; S888-K892 VanDerWaalsContact O-CG 3.29Å; S888-K892 WeakPolarHBondContact O-CG 3.32Å; S888-K892 PolarHBondContact O-N 3.03Å
889A66.4Low67.2Low31 Ų3179 Ų7926%0.25644%0.442SS..Hα-helixtrans-76.5-43174.700000111.6A885 L886 I887 K892 A893A885-A889 WeakPolarHBondContact O-CB 3.48Å; A885-A889 PolarHBondContact O-N 3.46Å; L886-A889 WeakPolarHBondContact O-CB 3.46Å; L886-A889 PolarHBondContact O-N 2.98Å; L886-A889 VanDerWaalsContact O-N 3.08Å; I887-A889 VanDerWaalsContact C-N 3.26Å; I887-A889 PolarHBondContact O-N 3.14Å; A889-K892 PolarHBondContact O-N 3.38Å; A889-A893 PolarHBondContact O-N 2.92Å
890V68.3Low68.2Low81 Ų8178 Ų7849%0.49143%0.434SS..Hα-helixtrans-63-48.8176174.30000111.1L886 I887 K892 A893 D894L886-V890 WeakPolarHBondContact O-CG2 3.38Å; L886-V890 PolarHBondContact O-N 3.45Å; I887-V890 PolarHBondContact O-N 3.09Å; V890-K892 PolarHBondContact O-N 3.29Å; V890-A893 WeakPolarHBondContact O-CA 3.49Å; V890-A893 WeakPolarHBondContact O-CB 3.24Å; V890-A893 PolarHBondContact O-N 3.24Å; V890-D894 PolarHBondContact O-N 2.9Å
891V70.8Confident69Low94 Ų9480.1 Ų80.157%0.5744%0.436SS*.Hα-helixtrans-58.4-34.6176.31720000111.7I887 S895I887-V891 HydrophobicContact CG2-CG2 4.31Å; I887-V891 WeakPolarHBondContact O-CG2 3.39Å; I887-V891 PolarHBondContact O-N 3.15Å; V891-S895 WeakPolarHBondContact O-CB 3.45Å; V891-S895 PolarHBondContact O-N 3.28Å
892K66.6Low70.2Confident127 Ų12775.9 Ų75.955%0.55241%0.414SS*.Hα-helixtrans-72-37.9173.2-79170.6-173.61570112.8S888 A889 V890 S895S888-K892 WeakPolarHBondContact O-CB 3.31Å; S888-K892 WeakPolarHBondContact O-CD 3.36Å; S888-K892 VanDerWaalsContact O-CG 3.29Å; S888-K892 WeakPolarHBondContact O-CG 3.32Å; S888-K892 PolarHBondContact O-N 3.03Å; A889-K892 PolarHBondContact O-N 3.38Å; V890-K892 PolarHBondContact O-N 3.29Å; K892-S895 PolarHBondContact O-N 3.14Å; K892-S895 PolarHBondContact O-OG 3.31Å
893A66.6Low70.8Confident24 Ų2476.4 Ų76.420%0.19841%0.411CS..Hα-helixtrans-63.9-45.9176.800000111.6A889 V890 S895 V896A889-A893 PolarHBondContact O-N 2.92Å; V890-A893 WeakPolarHBondContact O-CA 3.49Å; V890-A893 WeakPolarHBondContact O-CB 3.24Å; V890-A893 PolarHBondContact O-N 3.24Å; A893-S895 VanDerWaalsContact C-N 3.27Å; A893-S895 PolarHBondContact O-N 3.06Å; A893-V896 PolarHBondContact O-N 2.99Å
894D70.3Confident71.7Confident109 Ų10970.7 Ų70.758%0.58339%0.393SS*.Hα-helixtrans-69.2-23.7177.9-72.9-22.2000113V890 V896 V906V890-D894 PolarHBondContact O-N 2.9Å; D894-V896 PolarHBondContact O-N 2.91Å; D894-V906 WeakPolarHBondContact O-CG2 3.49Å
895S77.1Confident72.4Confident24 Ų2468.6 Ų68.617%0.16839%0.387CS..THydrogen-bonded Turntrans-71.9-9.7175.376.70000114.7V891 K892 A893 S905 V906V891-S895 WeakPolarHBondContact O-CB 3.45Å; V891-S895 PolarHBondContact O-N 3.28Å; K892-S895 PolarHBondContact O-N 3.14Å; K892-S895 PolarHBondContact O-OG 3.31Å; A893-S895 VanDerWaalsContact C-N 3.27Å; A893-S895 PolarHBondContact O-N 3.06Å; S895-S905 WeakPolarHBondContact O-CA 3.44Å; S895-V906 PolarHBondContact O-N 3.39Å
896V82.5Confident73.3Confident25 Ų2566.3 Ų66.315%0.15237%0.368CS..BIsolated β-bridgetrans-120.2140.1-174.9-178.40000111.1A893 D894 S898A893-V896 PolarHBondContact O-N 2.99Å; D894-V896 PolarHBondContact O-N 2.91Å; V896-S898 PolarHBondContact O-N 3.44Å
897C83.1Confident73.8Confident0 Ų069 Ų690%038%0.382CS..  trans-51.5125.4179.31730000112.7F899 C902 A904 V906 C921C897-F899 PolarHBondContact O-N 3.37Å; C897-C902 HydrophobicContact CB-CB 4.12Å; C897-A904 HydrophobicContact CB-CB 4.49Å; C897-A904 PolarHBondContact N-O 2.94Å; C897-V906 HydrophobicContact CB-CG1 3.81Å; C897-C921 HydrophobicContact CB-CB 4.15Å; C897-C921 PolarHBondContact SG-N 3.42Å; C897-C921 VanDerWaalsContact SG-N 3.36Å
898S83.1Confident74Confident40 Ų4070.9 Ų70.928%0.2840%0.397SS..  trans-71.110.6-177.4-46.10000115.4V896 Q919V896-S898 PolarHBondContact O-N 3.44Å; S898-Q919 PolarHBondContact N-O 2.65Å; S898-Q919 PolarHBondContact OG-O 3.16Å; S898-Q919 VanDerWaalsContact OG-O 3.08Å
899F82.7Confident74.4Confident64 Ų6473.6 Ų73.628%0.28141%0.406SS..SBendtrans-83.3136175.8-171.5-109.2000110.9C897 K901 C902 F920 H924 V929 H930C897-F899 PolarHBondContact O-N 3.37Å; F899-K901 PolarHBondContact O-N 3.38Å; F899-C902 HydrophobicContact CB-CB 4Å; F899-C902 HydrophobicContact CD1-CB 4.41Å; F899-C902 VanDerWaalsContact O-CB 3.31Å; F899-C902 WeakPolarHBondContact O-CB 3.47Å; F899-C902 PolarHBondContact O-N 3.41Å; F899-F920 HydrophobicContact CB-CD1 3.98Å; F899-F920 HydrophobicContact CB-CE1 4.15Å; F899-H924 HydrophobicContact CB-CB 3.83Å; F899-H924 AromaticContact CD1-CD2 3.61Å; F899-H924 AromaticContact CD1-CE1 3.93Å; F899-H924 AromaticContact CD1-CG 3.8Å; F899-H924 AromaticContact CD1-ND1 3.98Å; F899-H924 AromaticContact CD1-NE2 3.73Å; F899-H924 AromaticContact CE1-CD2 3.95Å; F899-H924 HydrophobicContact CG-CB 4.04Å; F899-H924 AromaticContact CG-CG 3.82Å; F899-V929 HydrophobicContact CE2-CG1 4.16Å; F899-V929 VanDerWaalsContact CE2-O 3.25Å; F899-V929 WeakPolarHBondContact CE2-O 3.47Å; F899-V929 HydrophobicContact CZ-CG1 4.28Å; F899-H930 HydrophobicContact CD2-CB 3.91Å; F899-H930 HydrophobicContact CE2-CB 4.35Å
900V71.8Confident75.1Confident99 Ų9973.4 Ų73.460%0.641%0.407SS*.THydrogen-bonded Turntrans-58.2125.5-175.2-178.50000110.2C902V900-C902 VanDerWaalsContact C-N 3.27Å; V900-C902 PolarHBondContact O-N 2.89Å
901K68.5Low75.6Confident197 Ų19773.9 Ų73.986%0.85740%0.404SS*.THydrogen-bonded Turntrans68.93.9-173.8-57.4168.1-177.41780116.4F899F899-K901 PolarHBondContact O-N 3.38Å
902C75.1Confident76.2Confident15 Ų1573.9 Ų73.910%0.10140%0.401CS..  trans-75.9147169.7-164.70000111.6C897 F899 V900 H924C897-C902 HydrophobicContact CB-CB 4.12Å; F899-C902 HydrophobicContact CB-CB 4Å; F899-C902 HydrophobicContact CD1-CB 4.41Å; F899-C902 VanDerWaalsContact O-CB 3.31Å; F899-C902 WeakPolarHBondContact O-CB 3.47Å; F899-C902 PolarHBondContact O-N 3.41Å; V900-C902 VanDerWaalsContact C-N 3.27Å; V900-C902 PolarHBondContact O-N 2.89Å; C902-H924 PolarHBondContact SG-CE1 3.41Å; C902-H924 PolarHBondContact SG-ND1 3.18Å; C902-H924 VanDerWaalsContact SG-ND1 3.43Å
903K77.3Confident77Confident135 Ų13568.1 Ų68.159%0.58738%0.377SS*.  trans-13014.9178.3-58.2-172.4-178-175.50113K867K867-K903 PolarHBondContact O-NZ 3.4Å
904A77.9Confident77.7Confident37 Ų3772.6 Ų72.631%0.30640%0.396SS..  trans-74.7137.3178.400000110.5C897 C921C897-A904 HydrophobicContact CB-CB 4.49Å; C897-A904 PolarHBondContact N-O 2.94Å; A904-C921 HydrophobicContact CB-CB 3.81Å
905S79.7Confident78.4Confident70 Ų7070 Ų7049%0.4938%0.378SS..BIsolated β-bridgetrans-68.4139.3171179.40000110.2S895 L907S895-S905 WeakPolarHBondContact O-CA 3.44Å; S905-L907 PolarHBondContact OG-N 3.33Å
906V79.9Confident78.6Confident3 Ų371 Ų712%0.01838%0.384CS..  trans-109.9-3.2176.2-72.10000113.4D894 S895 C897 T908 G910 Q919 C921D894-V906 WeakPolarHBondContact O-CG2 3.49Å; S895-V906 PolarHBondContact O-N 3.39Å; C897-V906 HydrophobicContact CB-CG1 3.81Å; V906-T908 PolarHBondContact O-N 3.33Å; V906-G910 VanDerWaalsContact O-CA 3.3Å; V906-G910 WeakPolarHBondContact O-CA 3.22Å; V906-G910 PolarHBondContact O-N 3.43Å; V906-Q919 HydrophobicContact CB-CB 4.37Å; V906-Q919 HydrophobicContact CG2-CB 4.11Å; V906-C921 HydrophobicContact CG1-CB 4.29Å
907L75.4Confident78.5Confident130 Ų13075.3 Ų75.368%0.68141%0.407SS*.THydrogen-bonded Turntrans-55.2-28.3-176.6-72.9169.8000115.5S905S905-L907 PolarHBondContact OG-N 3.33Å
908T67.3Low78.4Confident122 Ų12282.8 Ų82.875%0.74844%0.435SS*.THydrogen-bonded Turntrans-117.6-25.7-175.451.20000114.8V906V906-T908 PolarHBondContact O-N 3.33Å
909L72.6Confident78.4Confident118 Ų11884.8 Ų84.862%0.61844%0.44SS*.THydrogen-bonded Turntrans-141.125.8-174.7-67.8174.1000112.2L922L909-L922 HydrophobicContact CB-CD1 4.45Å
910G79.7Confident78.6Confident27 Ų2782 Ų8228%0.27843%0.428SS..  trans-72.5140171.100000111.8V906 F920V906-G910 VanDerWaalsContact O-CA 3.3Å; V906-G910 WeakPolarHBondContact O-CA 3.22Å; V906-G910 PolarHBondContact O-N 3.43Å; G910-F920 WeakPolarHBondContact CA-O 3.33Å
911Q79.1Confident79.3Confident91 Ų9177.9 Ų77.943%0.42540%0.403SS..EExtended strand (participates in β ladder)trans-114.4134.1168-71-169.9-6.200110.2F920 L922 H925Q911-F920 PolarHBondContact N-O 2.92Å; Q911-F920 PolarHBondContact O-N 3.13Å; Q911-L922 HydrophobicContact CG-CD2 4.09Å; Q911-H925 HydrophobicContact CB-CB 3.96Å; Q911-H925 PolarHBondContact OE1-CD2 3.21Å; Q911-H925 PolarHBondContact OE1-NE2 2.98Å
912L84.3Confident79.9Confident95 Ų9572.8 Ų72.850%0.49739%0.385SS..EExtended strand (participates in β ladder)trans-79.1127175.8-16890.7000109.7I914 Q919L912-I914 PolarHBondContact O-N 3.34Å; L912-Q919 HydrophobicContact CD1-CG 4Å
913C83.1Confident80.1Confident6 Ų675.7 Ų75.74%0.04141%0.406CS..EExtended strand (participates in β ladder)trans-78.9114168.4175.90000110.7Y915 C916 N917 R918 F920 H930C913-Y915 PolarHBondContact O-N 3.22Å; C913-Y915 PolarHBondContact SG-N 3.46Å; C913-C916 PolarHBondContact O-N 3.42Å; C913-N917 WeakPolarHBondContact O-CA 3.49Å; C913-N917 PolarHBondContact O-N 3.17Å; C913-R918 PolarHBondContact N-O 3.12Å; C913-F920 HydrophobicContact CB-CD2 4.07Å; C913-F920 HydrophobicContact CB-CE2 3.88Å; C913-H930 WeakPolarHBondContact CB-NE2 3.41Å; C913-H930 PolarHBondContact SG-NE2 3.01Å
914I81.2Confident80.4Confident118 Ų11871.2 Ų71.261%0.60539%0.386SS*.THydrogen-bonded Turntrans-59.9-9.4178.663.5173.3000115.4L912L912-I914 PolarHBondContact O-N 3.34Å
915Y84.7Confident80.6Confident54 Ų5472.3 Ų72.321%0.21239%0.385CS..THydrogen-bonded Turntrans-101.5-13.1-178.2-54.7-67.5000114.4C913 P927 C932 K935 A936 H939C913-Y915 PolarHBondContact O-N 3.22Å; C913-Y915 PolarHBondContact SG-N 3.46Å; Y915-P927 HydrophobicContact CD2-CB 4.15Å; Y915-P927 HydrophobicContact CD2-CG 3.98Å; Y915-P927 HydrophobicContact CE2-CB 4.31Å; Y915-P927 HydrophobicContact CE2-CG 3.85Å; Y915-C932 HydrophobicContact CD2-CB 4.36Å; Y915-C932 HydrophobicContact CG-CB 4.49Å; Y915-K935 HydrophobicContact CD1-CB 3.98Å; Y915-K935 HydrophobicContact CG-CB 4.17Å; Y915-K935 PolarHBondContact O-NZ 3.26Å; Y915-A936 HydrophobicContact CD2-CB 4.25Å; Y915-A936 HydrophobicContact CE2-CB 3.61Å; Y915-H939 HydrophobicContact CE1-CB 4.15Å; Y915-H939 PolarHBondContact OH-ND1 2.84Å
916C81.6Confident80.8Confident44 Ų4472.4 Ų72.430%0.29738%0.38SS..THydrogen-bonded Turntrans-140.5-1.5176.865.40000114.8C913 R918 C932C913-C916 PolarHBondContact O-N 3.42Å; C916-R918 PolarHBondContact O-N 2.94Å; C916-C932 VanDerWaalsContact SG-SG 3.69Å
917N80.3Confident80.9Confident117 Ų11773.6 Ų73.663%0.62639%0.387SS*.THydrogen-bonded Turntrans52.235.4179.2-63.3-3.8000114.7C913C913-N917 WeakPolarHBondContact O-CA 3.49Å; C913-N917 PolarHBondContact O-N 3.17Å
918R81.8Confident81.3Confident156 Ų15672.2 Ų72.259%0.58938%0.377SS*.EExtended strand (participates in β ladder)trans-109.9148.8174-66.9178.6-174.7-169.7-1110.8C913 C916 F920C913-R918 PolarHBondContact N-O 3.12Å; C916-R918 PolarHBondContact O-N 2.94Å; R918-F920 HydrophobicContact CB-CE2 3.68Å; R918-F920 HydrophobicContact CB-CZ 3.88Å; R918-F920 WeakPolarHBondContact O-CD2 3.43Å; R918-F920 WeakPolarHBondContact O-CE2 3.33Å
919Q83.1Confident82Confident82 Ų8269.4 Ų69.438%0.38336%0.36SS..EExtended strand (participates in β ladder)trans-90133.1178-72.3-167.61.900112.2S898 V906 L912S898-Q919 PolarHBondContact N-O 2.65Å; S898-Q919 PolarHBondContact OG-O 3.16Å; S898-Q919 VanDerWaalsContact OG-O 3.08Å; V906-Q919 HydrophobicContact CB-CB 4.37Å; V906-Q919 HydrophobicContact CG2-CB 4.11Å; L912-Q919 HydrophobicContact CD1-CG 4Å
920F86.7Confident82.3Confident6 Ų665.2 Ų65.23%0.02634%0.337CS..EExtended strand (participates in β ladder)trans-129.3149.2179.1-61-85.3000110.8F899 G910 Q911 C913 R918 H924 H925 H930F899-F920 HydrophobicContact CB-CD1 3.98Å; F899-F920 HydrophobicContact CB-CE1 4.15Å; G910-F920 WeakPolarHBondContact CA-O 3.33Å; Q911-F920 PolarHBondContact N-O 2.92Å; Q911-F920 PolarHBondContact O-N 3.13Å; C913-F920 HydrophobicContact CB-CD2 4.07Å; C913-F920 HydrophobicContact CB-CE2 3.88Å; R918-F920 HydrophobicContact CB-CE2 3.68Å; R918-F920 HydrophobicContact CB-CZ 3.88Å; R918-F920 WeakPolarHBondContact O-CD2 3.43Å; R918-F920 WeakPolarHBondContact O-CE2 3.33Å; F920-H924 HydrophobicContact CB-CB 4.32Å; F920-H924 HydrophobicContact CD1-CB 4.27Å; F920-H925 HydrophobicContact CB-CB 4.1Å; F920-H930 HydrophobicContact CD1-CB 4.33Å; F920-H930 AromaticContact CD2-CE1 3.96Å; F920-H930 AromaticContact CD2-ND1 3.96Å; F920-H930 HydrophobicContact CE1-CB 3.64Å; F920-H930 AromaticContact CE1-CG 3.78Å; F920-H930 HydrophobicContact CE2-CB 4.48Å; F920-H930 AromaticContact CE2-CD2 3.64Å; F920-H930 AromaticContact CE2-CE1 3.78Å; F920-H930 AromaticContact CE2-CG 3.74Å; F920-H930 AromaticContact CE2-ND1 3.83Å; F920-H930 AromaticContact CE2-NE2 3.7Å; F920-H930 HydrophobicContact CZ-CB 3.74Å; F920-H930 AromaticContact CZ-CD2 3.53Å; F920-H930 AromaticContact CZ-CG 3.45Å; F920-H930 VanDerWaalsContact CZ-CG 3.45Å; F920-H930 AromaticContact CZ-ND1 3.95Å
921C85.4Confident82.3Confident13 Ų1367.3 Ų67.39%0.08836%0.358CS..  trans-69.4161.5168.961.10000110.4C897 A904 V906 S923 H924 H925C897-C921 HydrophobicContact CB-CB 4.15Å; C897-C921 PolarHBondContact SG-N 3.42Å; C897-C921 VanDerWaalsContact SG-N 3.36Å; A904-C921 HydrophobicContact CB-CB 3.81Å; V906-C921 HydrophobicContact CG1-CB 4.29Å; C921-S923 PolarHBondContact O-N 3.22Å; C921-S923 PolarHBondContact SG-OG 3.12Å; C921-H924 PolarHBondContact O-N 3.08Å; C921-H924 PolarHBondContact SG-ND1 2.89Å; C921-H925 PolarHBondContact O-N 2.86Å
922L81.6Confident82.6Confident90 Ų9063.5 Ų63.547%0.47134%0.342SS..THydrogen-bonded Turntrans-53.8-25.5-174.6-60.4173.7000114.5L909 Q911 H925L909-L922 HydrophobicContact CB-CD1 4.45Å; Q911-L922 HydrophobicContact CG-CD2 4.09Å; L922-H925 PolarHBondContact O-CE1 3.4Å; L922-H925 PolarHBondContact O-ND1 3.47Å
923S79.8Confident82.6Confident76 Ų7659.2 Ų59.253%0.53132%0.321SS..THydrogen-bonded Turntrans-78.2-19.7174.762.90000115.4C921C921-S923 PolarHBondContact O-N 3.22Å; C921-S923 PolarHBondContact SG-OG 3.12Å
924H83.8Confident82.3Confident40 Ų4064.7 Ų64.719%0.18535%0.349CS..THydrogen-bonded Turntrans-122.1-3.5-173.7-56.5126000113.9F899 C902 F920 C921 I926 V929 H930F899-H924 HydrophobicContact CB-CB 3.83Å; F899-H924 AromaticContact CD1-CD2 3.61Å; F899-H924 AromaticContact CD1-CE1 3.93Å; F899-H924 AromaticContact CD1-CG 3.8Å; F899-H924 AromaticContact CD1-ND1 3.98Å; F899-H924 AromaticContact CD1-NE2 3.73Å; F899-H924 AromaticContact CE1-CD2 3.95Å; F899-H924 HydrophobicContact CG-CB 4.04Å; F899-H924 AromaticContact CG-CG 3.82Å; C902-H924 PolarHBondContact SG-CE1 3.41Å; C902-H924 PolarHBondContact SG-ND1 3.18Å; C902-H924 VanDerWaalsContact SG-ND1 3.43Å; F920-H924 HydrophobicContact CB-CB 4.32Å; F920-H924 HydrophobicContact CD1-CB 4.27Å; C921-H924 PolarHBondContact O-N 3.08Å; C921-H924 PolarHBondContact SG-ND1 2.89Å; H924-I926 PolarHBondContact O-N 3.01Å; H924-V929 HydrophobicContact CB-CG1 4.48Å; H924-H930 PolarHBondContact O-ND1 2.91Å
925H82.7Confident82.2Confident61 Ų6164.8 Ų64.828%0.28235%0.346SS..  trans-65.2-19.3179.185-78.3000114.4Q911 F920 C921 L922 H930Q911-H925 HydrophobicContact CB-CB 3.96Å; Q911-H925 PolarHBondContact OE1-CD2 3.21Å; Q911-H925 PolarHBondContact OE1-NE2 2.98Å; F920-H925 HydrophobicContact CB-CB 4.1Å; C921-H925 PolarHBondContact O-N 2.86Å; L922-H925 PolarHBondContact O-CE1 3.4Å; L922-H925 PolarHBondContact O-ND1 3.47Å; H925-H930 PolarHBondContact O-CE1 3.49Å; H925-H930 VanDerWaalsContact O-CE1 3.31Å
926I83.9Confident82Confident72 Ų7262.9 Ų62.937%0.36934%0.341SS..SBendtrans-63.1123.2179.9-63175.2000109H924 E928 V929 H930H924-I926 PolarHBondContact O-N 3.01Å; I926-E928 VanDerWaalsContact C-N 3.25Å; I926-E928 HydrophobicContact CG2-CB 4.23Å; I926-E928 VanDerWaalsContact CG2-OE2 3.25Å; I926-E928 WeakPolarHBondContact CG2-OE2 3.42Å; I926-E928 PolarHBondContact O-N 3.49Å; I926-E928 VanDerWaalsContact O-N 3.15Å; I926-V929 HydrophobicContact CB-CB 4.45Å; I926-V929 HydrophobicContact CB-CG2 3.85Å; I926-V929 HydrophobicContact CG2-CG2 4.08Å; I926-V929 WeakPolarHBondContact O-CB 3.24Å; I926-V929 PolarHBondContact O-N 3.36Å; I926-H930 PolarHBondContact O-CE1 3.43Å; I926-H930 PolarHBondContact O-ND1 2.99Å; I926-H930 VanDerWaalsContact O-ND1 3.14Å
927P82.1Confident81.7Confident27 Ų2765.3 Ų65.318%0.17535%0.346CS..THydrogen-bonded Turntrans-52.6-38.4-175.2-30.337000114.6Y915 V929 G931 C932 G933 A936Y915-P927 HydrophobicContact CD2-CB 4.15Å; Y915-P927 HydrophobicContact CD2-CG 3.98Å; Y915-P927 HydrophobicContact CE2-CB 4.31Å; Y915-P927 HydrophobicContact CE2-CG 3.85Å; P927-V929 VanDerWaalsContact C-N 3.27Å; P927-V929 PolarHBondContact O-N 3.18Å; P927-G931 PolarHBondContact O-N 3.32Å; P927-C932 HydrophobicContact CB-CB 3.95Å; P927-C932 CarbonylContact O-C 3.42Å; P927-C932 WeakPolarHBondContact O-CA 3.42Å; P927-C932 PolarHBondContact O-N 3.11Å; P927-G933 PolarHBondContact O-N 3.26Å; P927-A936 HydrophobicContact CB-CB 3.81Å; P927-A936 HydrophobicContact CG-CB 4.12Å
928E83.6Confident81.3Confident101 Ų10162.9 Ų62.947%0.47234%0.339SS..THydrogen-bonded Turntrans-60.6-33.6177.2-70.172.5-165.700112.8I926I926-E928 VanDerWaalsContact C-N 3.25Å; I926-E928 HydrophobicContact CG2-CB 4.23Å; I926-E928 VanDerWaalsContact CG2-OE2 3.25Å; I926-E928 WeakPolarHBondContact CG2-OE2 3.42Å; I926-E928 PolarHBondContact O-N 3.49Å; I926-E928 VanDerWaalsContact O-N 3.15Å
929V81.9Confident81.1Confident63 Ų6359.2 Ų59.238%0.38233%0.328SS..THydrogen-bonded Turntrans-74.6-38.3-174177.70000111.5F899 H924 I926 P927F899-V929 HydrophobicContact CE2-CG1 4.16Å; F899-V929 VanDerWaalsContact CE2-O 3.25Å; F899-V929 WeakPolarHBondContact CE2-O 3.47Å; F899-V929 HydrophobicContact CZ-CG1 4.28Å; H924-V929 HydrophobicContact CB-CG1 4.48Å; I926-V929 HydrophobicContact CB-CB 4.45Å; I926-V929 HydrophobicContact CB-CG2 3.85Å; I926-V929 HydrophobicContact CG2-CG2 4.08Å; I926-V929 WeakPolarHBondContact O-CB 3.24Å; I926-V929 PolarHBondContact O-N 3.36Å; P927-V929 VanDerWaalsContact C-N 3.27Å; P927-V929 PolarHBondContact O-N 3.18Å
930H77.3Confident80.3Confident31 Ų3157.5 Ų57.514%0.14433%0.328CS..THydrogen-bonded Turntrans-106.521.2-178.265.5-98.6000113.9F899 C913 F920 H924 H925 I926F899-H930 HydrophobicContact CD2-CB 3.91Å; F899-H930 HydrophobicContact CE2-CB 4.35Å; C913-H930 WeakPolarHBondContact CB-NE2 3.41Å; C913-H930 PolarHBondContact SG-NE2 3.01Å; F920-H930 HydrophobicContact CD1-CB 4.33Å; F920-H930 AromaticContact CD2-CE1 3.96Å; F920-H930 AromaticContact CD2-ND1 3.96Å; F920-H930 HydrophobicContact CE1-CB 3.64Å; F920-H930 AromaticContact CE1-CG 3.78Å; F920-H930 HydrophobicContact CE2-CB 4.48Å; F920-H930 AromaticContact CE2-CD2 3.64Å; F920-H930 AromaticContact CE2-CE1 3.78Å; F920-H930 AromaticContact CE2-CG 3.74Å; F920-H930 AromaticContact CE2-ND1 3.83Å; F920-H930 AromaticContact CE2-NE2 3.7Å; F920-H930 HydrophobicContact CZ-CB 3.74Å; F920-H930 AromaticContact CZ-CD2 3.53Å; F920-H930 AromaticContact CZ-CG 3.45Å; F920-H930 VanDerWaalsContact CZ-CG 3.45Å; F920-H930 AromaticContact CZ-ND1 3.95Å; H924-H930 PolarHBondContact O-ND1 2.91Å; H925-H930 PolarHBondContact O-CE1 3.49Å; H925-H930 VanDerWaalsContact O-CE1 3.31Å; I926-H930 PolarHBondContact O-CE1 3.43Å; I926-H930 PolarHBondContact O-ND1 2.99Å; I926-H930 VanDerWaalsContact O-ND1 3.14Å
931G79.9Confident79.5Confident70 Ų7066.2 Ų66.272%0.72236%0.361SS*.THydrogen-bonded Turntrans84.89.7169.800000116.6P927P927-G931 PolarHBondContact O-N 3.32Å
932C85.6Confident78.4Confident11 Ų1172.1 Ų72.17%0.07439%0.388CS..  trans-93.40.3173-74.30000114.2Y915 C916 P927 D934 K935 A936Y915-C932 HydrophobicContact CD2-CB 4.36Å; Y915-C932 HydrophobicContact CG-CB 4.49Å; C916-C932 VanDerWaalsContact SG-SG 3.69Å; P927-C932 HydrophobicContact CB-CB 3.95Å; P927-C932 CarbonylContact O-C 3.42Å; P927-C932 WeakPolarHBondContact O-CA 3.42Å; P927-C932 PolarHBondContact O-N 3.11Å; C932-D934 VanDerWaalsContact C-N 3.28Å; C932-D934 PolarHBondContact O-N 3.33Å; C932-K935 WeakPolarHBondContact O-CB 3.4Å; C932-K935 PolarHBondContact O-N 3.01Å; C932-K935 VanDerWaalsContact O-N 3.08Å; C932-A936 PolarHBondContact O-N 3.25Å; C932-A936 VanDerWaalsContact O-N 3.08Å
933G85.4Confident77.3Confident6 Ų674.5 Ų74.56%0.06239%0.391CS..Hα-helixtrans-54.9-35.2-173.800000115P927 A936 K937P927-G933 PolarHBondContact O-N 3.26Å; G933-A936 PolarHBondContact O-N 3.47Å; G933-K937 WeakPolarHBondContact O-CB 3.39Å; G933-K937 VanDerWaalsContact O-CG 3.26Å; G933-K937 WeakPolarHBondContact O-CG 3.38Å; G933-K937 PolarHBondContact O-N 3.22Å
934D76.8Confident76.3Confident120 Ų12074.5 Ų74.564%0.64239%0.385SS*.Hα-helixtrans-77-27.7-179.6-63.7-31.2000113.2C932 K937 S938C932-D934 VanDerWaalsContact C-N 3.28Å; C932-D934 PolarHBondContact O-N 3.33Å; D934-K937 IonicContact OD1-NZ 2.72Å; D934-K937 PolarHBondContact OD1-NZ 2.86Å; D934-S938 WeakPolarHBondContact O-CB 3.41Å; D934-S938 PolarHBondContact O-N 2.88Å; D934-S938 PolarHBondContact O-OG 2.8Å
935K79.3Confident75.1Confident121 Ų12177.9 Ų77.953%0.52641%0.412SS..Hα-helixtrans-68.6-39.2167.3-67.8-178.6176.9-1780111.3Y915 C932 S938 H939Y915-K935 HydrophobicContact CD1-CB 3.98Å; Y915-K935 HydrophobicContact CG-CB 4.17Å; Y915-K935 PolarHBondContact O-NZ 3.26Å; C932-K935 WeakPolarHBondContact O-CB 3.4Å; C932-K935 PolarHBondContact O-N 3.01Å; C932-K935 VanDerWaalsContact O-N 3.08Å; K935-S938 PolarHBondContact O-OG 2.72Å; K935-H939 WeakPolarHBondContact O-CB 3.41Å; K935-H939 PolarHBondContact O-N 2.74Å
936A78.9Confident73.5Confident13 Ų1383.7 Ų83.711%0.10744%0.437CS..Hα-helixtrans-64.3-44.6174.800000111.7Y915 P927 C932 G933 H939 A940Y915-A936 HydrophobicContact CD2-CB 4.25Å; Y915-A936 HydrophobicContact CE2-CB 3.61Å; P927-A936 HydrophobicContact CB-CB 3.81Å; P927-A936 HydrophobicContact CG-CB 4.12Å; C932-A936 PolarHBondContact O-N 3.25Å; C932-A936 VanDerWaalsContact O-N 3.08Å; G933-A936 PolarHBondContact O-N 3.47Å; A936-H939 PolarHBondContact O-N 3.45Å; A936-A940 WeakPolarHBondContact O-CB 3.34Å; A936-A940 PolarHBondContact O-N 3.42Å
937K75.6Confident72.1Confident95 Ų9585.5 Ų85.541%0.41344%0.444SS..Hα-helixtrans-65.2-39.2176.6-71.1167.3-163.7160.30113.1G933 D934 R941G933-K937 WeakPolarHBondContact O-CB 3.39Å; G933-K937 VanDerWaalsContact O-CG 3.26Å; G933-K937 WeakPolarHBondContact O-CG 3.38Å; G933-K937 PolarHBondContact O-N 3.22Å; D934-K937 IonicContact OD1-NZ 2.72Å; D934-K937 PolarHBondContact OD1-NZ 2.86Å; K937-R941 WeakPolarHBondContact O-CB 3.4Å; K937-R941 VanDerWaalsContact O-CG 3.26Å; K937-R941 WeakPolarHBondContact O-CG 3.44Å; K937-R941 PolarHBondContact O-N 3.27Å
938S73.3Confident70.7Confident67 Ų6786.4 Ų86.447%0.46946%0.458SS..Hα-helixtrans-68.2-42.6177.466.10000111.5D934 K935 R941 M942D934-S938 WeakPolarHBondContact O-CB 3.41Å; D934-S938 PolarHBondContact O-N 2.88Å; D934-S938 PolarHBondContact O-OG 2.8Å; K935-S938 PolarHBondContact O-OG 2.72Å; S938-R941 PolarHBondContact O-N 2.87Å; S938-M942 WeakPolarHBondContact O-CB 3.45Å; S938-M942 PolarHBondContact O-N 2.85Å
939H76Confident69Low79 Ų7986.1 Ų86.137%0.36646%0.463SS..Hα-helixtrans-60.8-44.2173.8-174.8-114.9000112.2Y915 K935 A936 M942 R943Y915-H939 HydrophobicContact CE1-CB 4.15Å; Y915-H939 PolarHBondContact OH-ND1 2.84Å; K935-H939 WeakPolarHBondContact O-CB 3.41Å; K935-H939 PolarHBondContact O-N 2.74Å; A936-H939 PolarHBondContact O-N 3.45Å; H939-M942 PolarHBondContact O-N 3.02Å; H939-R943 PolarHBondContact O-N 3.13Å
940A67.9Low67.3Low46 Ų4686.5 Ų86.538%0.3846%0.463SS..Hα-helixtrans-62.9-42.6175.500000112.8A936 M942 R943 I944A936-A940 WeakPolarHBondContact O-CB 3.34Å; A936-A940 PolarHBondContact O-N 3.42Å; A940-M942 VanDerWaalsContact C-N 3.31Å; A940-M942 PolarHBondContact O-N 3.36Å; A940-R943 PolarHBondContact O-N 3.25Å; A940-I944 VanDerWaalsContact O-CG1 3.3Å; A940-I944 WeakPolarHBondContact O-CG1 3.38Å; A940-I944 PolarHBondContact O-N 3.48Å
941R69.3Low65.9Low189 Ų18994.1 Ų94.171%0.71349%0.492SS*.Hα-helixtrans-61.5-39.6174.2-74.2170.8-177.7-175.71.6111.9K937 S938 I944 S945K937-R941 WeakPolarHBondContact O-CB 3.4Å; K937-R941 VanDerWaalsContact O-CG 3.26Å; K937-R941 WeakPolarHBondContact O-CG 3.44Å; K937-R941 PolarHBondContact O-N 3.27Å; S938-R941 PolarHBondContact O-N 2.87Å; R941-I944 PolarHBondContact O-N 3.46Å; R941-S945 PolarHBondContact O-N 2.86Å
942M62.5Low63.9Low136 Ų13696.4 Ų96.467%0.6750%0.503SS*.Hα-helixtrans-66.3-41.2178.2-164.7177.4-72.400111.7S938 H939 A940 S945 K946S938-M942 WeakPolarHBondContact O-CB 3.45Å; S938-M942 PolarHBondContact O-N 2.85Å; H939-M942 PolarHBondContact O-N 3.02Å; A940-M942 VanDerWaalsContact C-N 3.31Å; A940-M942 PolarHBondContact O-N 3.36Å; M942-S945 PolarHBondContact O-N 2.88Å; M942-K946 WeakPolarHBondContact O-CB 3.42Å; M942-K946 PolarHBondContact O-N 2.94Å
943R57.6Low62.2Low140 Ų14099.8 Ų99.853%0.52854%0.541SS..Hα-helixtrans-61-49.4170.5-91-163.5169.5149.92.9112.9H939 A940 S945 K946 E947H939-R943 PolarHBondContact O-N 3.13Å; A940-R943 PolarHBondContact O-N 3.25Å; R943-S945 PolarHBondContact O-N 2.95Å; R943-K946 WeakPolarHBondContact O-CA 3.2Å; R943-K946 PolarHBondContact O-N 3.23Å; R943-E947 WeakPolarHBondContact CD-OE1 3.42Å; R943-E947 WeakPolarHBondContact CG-OE1 3.36Å; R943-E947 IonicContact NE-OE1 2.74Å; R943-E947 PolarHBondContact NE-OE1 2.98Å; R943-E947 WeakPolarHBondContact O-CB 3.41Å; R943-E947 PolarHBondContact O-N 3.18Å
944I58.2Low60.2Low77 Ų77102.1 Ų102.140%0.39556%0.556SS.*Hα-helixtrans-58.6-35.1179.8-67.3163.6000111.5A940 R941 K946 G948 L950A940-I944 VanDerWaalsContact O-CG1 3.3Å; A940-I944 WeakPolarHBondContact O-CG1 3.38Å; A940-I944 PolarHBondContact O-N 3.48Å; R941-I944 PolarHBondContact O-N 3.46Å; I944-K946 VanDerWaalsContact C-N 3.3Å; I944-K946 PolarHBondContact O-N 3.25Å; I944-G948 PolarHBondContact O-N 2.95Å; I944-L950 HydrophobicContact CG2-CD2 3.9Å
945S59.8Low58.6Low110 Ų11099.4 Ų99.477%0.76956%0.556SS**Hα-helixtrans-70.2-20.9174.3-171.20000114.5R941 M942 R943R941-S945 PolarHBondContact O-N 2.86Å; M942-S945 PolarHBondContact O-N 2.88Å; R943-S945 PolarHBondContact O-N 2.95Å
946K49.5Very low56.8Low184 Ų184103.6 Ų103.680%0.857%0.574SS**Hα-helixtrans-105.6-31-172.7-152.7179.6-173.7-171.10112.7M942 R943 I944M942-K946 WeakPolarHBondContact O-CB 3.42Å; M942-K946 PolarHBondContact O-N 2.94Å; R943-K946 WeakPolarHBondContact O-CA 3.2Å; R943-K946 PolarHBondContact O-N 3.23Å; I944-K946 VanDerWaalsContact C-N 3.3Å; I944-K946 PolarHBondContact O-N 3.25Å
947E54.8Low55.1Low109 Ų109110.2 Ų110.251%0.50960%0.601SS.*Hα-helixtrans-108.5-13.5-173.6-65.4162.4-167.700112.7R943 V949R943-E947 WeakPolarHBondContact CD-OE1 3.42Å; R943-E947 WeakPolarHBondContact CG-OE1 3.36Å; R943-E947 IonicContact NE-OE1 2.74Å; R943-E947 PolarHBondContact NE-OE1 2.98Å; R943-E947 WeakPolarHBondContact O-CB 3.41Å; R943-E947 PolarHBondContact O-N 3.18Å; E947-V949 PolarHBondContact O-N 3.31Å
948G51.6Low53.6Low47 Ų47113.4 Ų113.449%0.48562%0.622SS.*  trans72.1-16.3169.100000117.4I944I944-G948 PolarHBondContact O-N 2.95Å
949V48.2Very low52.3Low95 Ų95119.8 Ų119.858%0.57664%0.641SS**  trans-84.6140-179.9-179.30000111.5E947E947-V949 PolarHBondContact O-N 3.31Å
950L45.8Very low51Low71 Ų71121.5 Ų121.537%0.37266%0.662SS.*  trans-110.1126.2175.6-73.3166.2000109.8I944 S954 K957I944-L950 HydrophobicContact CG2-CD2 3.9Å; L950-S954 WeakPolarHBondContact CD2-OG 3.33Å; L950-K957 HydrophobicContact CD1-CD 4.26Å; L950-K957 HydrophobicContact CD1-CG 3.93Å
951Y47.3Very low50.2Low191 Ų191124.7 Ų124.775%0.74967%0.672SS**  trans-81155.2173.8-74.9-89.3000111.7G953 S954Y951-G953 PolarHBondContact O-N 2.85Å; Y951-S954 PolarHBondContact O-N 3.17Å; Y951-S954 PolarHBondContact O-OG 3.21Å
952A38.4Very low49.8Very low117 Ų117119.4 Ų119.497%0.96766%0.658SS**THydrogen-bonded Turntrans-60.3110.1178.700000111.1
953G49.5Very low49.7Very low83 Ų83117.5 Ų117.586%0.85666%0.656SS**THydrogen-bonded Turntrans137.2-27.2-176.400000113.5Y951Y951-G953 PolarHBondContact O-N 2.85Å
954S43.6Very low50.1Low55 Ų55116.8 Ų116.839%0.38566%0.663SS.*SBendtrans-76.5130.1168.851.70000111L950 Y951L950-S954 WeakPolarHBondContact CD2-OG 3.33Å; Y951-S954 PolarHBondContact O-N 3.17Å; Y951-S954 PolarHBondContact O-OG 3.21Å
955G44.3Very low50.3Low62 Ų62119.2 Ų119.264%0.63967%0.671SS**PPolyproline II helixtrans-58.4161.9179.200000113.9K957G955-K957 PolarHBondContact O-N 2.84Å
956K40.1Very low50.4Low209 Ų209120.3 Ų120.391%0.90966%0.661SS**PPolyproline II helixtrans-56.3136.6-178.2-68-179.1178.7176.90111D958K956-D958 PolarHBondContact O-N 3.29Å
957K44.5Very low51.5Low153 Ų153115.1 Ų115.167%0.66565%0.645SS**PPolyproline II helixtrans-52.8126.9165.9-85.9177.9174.6171.60109.2L950 G955 K959L950-K957 HydrophobicContact CD1-CD 4.26Å; L950-K957 HydrophobicContact CD1-CG 3.93Å; G955-K957 PolarHBondContact O-N 2.84Å; K957-K959 PolarHBondContact O-N 3.27Å
958D42.8Very low52.6Low161 Ų161116.5 Ų116.586%0.86165%0.647SS**PPolyproline II helixtrans-57.5131.5160.6-82.5-43.4000108.6K956 S960K956-D958 PolarHBondContact O-N 3.29Å; D958-S960 PolarHBondContact O-N 3.45Å
959K46.4Very low53.5Low202 Ų202118.6 Ų118.688%0.87865%0.646SS**PPolyproline II helixtrans-63.2127.7173.9-72.6-174.9174.6-173.80107.9K957 L961K957-K959 PolarHBondContact O-N 3.27Å; K959-L961 PolarHBondContact O-N 3.07Å; K959-L961 VanDerWaalsContact O-N 3.14Å
960S48.3Very low54.5Low115 Ų115119.2 Ų119.280%0.80464%0.643SS**PPolyproline II helixtrans-50.5122.3173.851.80000109.7D958 D962D958-S960 PolarHBondContact O-N 3.45Å; S960-D962 PolarHBondContact O-N 3.15Å
961L51.3Low56.1Low112 Ų112124.8 Ų124.859%0.58666%0.659SS**PPolyproline II helixtrans-53.7130.2177.3-86.3159.3000109.9K959K959-L961 PolarHBondContact O-N 3.07Å; K959-L961 VanDerWaalsContact O-N 3.14Å
962D61.2Low57.3Low79 Ų79121.2 Ų121.242%0.42265%0.647SS.*  trans-41126.1172.5176-18.3000110.2S960 N964 K965 K966S960-D962 PolarHBondContact O-N 3.15Å; D962-N964 PolarHBondContact O-N 2.89Å; D962-N964 WeakPolarHBondContact OD1-CB 3.48Å; D962-N964 PolarHBondContact OD1-N 2.86Å; D962-K965 HydrophobicContact CB-CB 4.27Å; D962-K965 HydrophobicContact CB-CG 4.49Å; D962-K965 WeakPolarHBondContact O-CA 3.46Å; D962-K965 WeakPolarHBondContact O-CB 3.43Å; D962-K965 PolarHBondContact O-N 3.08Å; D962-K966 PolarHBondContact O-N 2.97Å
963P60.3Low58.9Low96 Ų96120.5 Ų120.562%0.62363%0.627SS**Hα-helixtrans-48.2-37.9-179.2-29.735.6000113.5K966 V967P963-K966 WeakPolarHBondContact O-CB 3.41Å; P963-K966 PolarHBondContact O-N 2.94Å; P963-V967 WeakPolarHBondContact O-CG2 3.41Å; P963-V967 PolarHBondContact O-N 3.07Å
964N65.5Low60.1Low125 Ų125120.5 Ų120.567%0.66861%0.607SS**Hα-helixtrans-68.9-38179.6-66.3-40.9000112.1D962 Y968D962-N964 PolarHBondContact O-N 2.89Å; D962-N964 WeakPolarHBondContact OD1-CB 3.48Å; D962-N964 PolarHBondContact OD1-N 2.86Å; N964-Y968 WeakPolarHBondContact O-CB 3.38Å; N964-Y968 PolarHBondContact O-N 3.15Å
965K63.7Low61.7Low128 Ų128121 Ų12156%0.55761%0.61SS**Hα-helixtrans-68.8-36.6171.6-80.7-178.5174.7173.20112D962 Y968 L969D962-K965 HydrophobicContact CB-CB 4.27Å; D962-K965 HydrophobicContact CB-CG 4.49Å; D962-K965 WeakPolarHBondContact O-CA 3.46Å; D962-K965 WeakPolarHBondContact O-CB 3.43Å; D962-K965 PolarHBondContact O-N 3.08Å; K965-Y968 PolarHBondContact O-N 3.31Å; K965-L969 WeakPolarHBondContact O-CB 3.47Å; K965-L969 VanDerWaalsContact O-CG 3.28Å; K965-L969 WeakPolarHBondContact O-CG 3.24Å; K965-L969 PolarHBondContact O-N 3.38Å
966K62.3Low63Low132 Ų132125 Ų12557%0.57461%0.61SS**Hα-helixtrans-62.7-48.4175.9-169179.8178.4-1750110.9D962 P963 Y968 L969 Q970D962-K966 PolarHBondContact O-N 2.97Å; P963-K966 WeakPolarHBondContact O-CB 3.41Å; P963-K966 PolarHBondContact O-N 2.94Å; K966-Y968 PolarHBondContact O-N 2.73Å; K966-L969 PolarHBondContact O-N 3.27Å; K966-Q970 WeakPolarHBondContact O-CB 3.1Å; K966-Q970 PolarHBondContact O-N 3.23Å
967V72.3Confident64.6Low76 Ų76119.2 Ų119.246%0.46159%0.589SS.*Hα-helixtrans-63-41.2176.3173.60000111.9P963 Q970 R971P963-V967 WeakPolarHBondContact O-CG2 3.41Å; P963-V967 PolarHBondContact O-N 3.07Å; V967-Q970 PolarHBondContact O-N 3.05Å; V967-R971 WeakPolarHBondContact O-CG 3.34Å; V967-R971 PolarHBondContact O-N 2.81Å
968Y77.8Confident66Low138 Ų138119.5 Ų119.554%0.54159%0.59SS.*Hα-helixtrans-62.2-46.2175.2176.1-95.9000112.5N964 K965 K966 Q970 R971 K972N964-Y968 WeakPolarHBondContact O-CB 3.38Å; N964-Y968 PolarHBondContact O-N 3.15Å; K965-Y968 PolarHBondContact O-N 3.31Å; K966-Y968 PolarHBondContact O-N 2.73Å; Y968-Q970 VanDerWaalsContact C-N 3.31Å; Y968-Q970 PolarHBondContact O-N 2.97Å; Y968-R971 PolarHBondContact O-N 3.36Å; Y968-K972 HydrophobicContact CE1-CD 3.97Å; Y968-K972 WeakPolarHBondContact O-CB 3.26Å; Y968-K972 PolarHBondContact O-N 3.17Å; Y968-K972 PolarHBondContact OH-NZ 2.96Å; Y968-K972 VanDerWaalsContact OH-NZ 3.16Å
969L70Confident67.4Low91 Ų91115.7 Ų115.748%0.47657%0.57SS.*Hα-helixtrans-64-37.2177.1-73.8169.5000111.9K965 K966 K972 L973K965-L969 WeakPolarHBondContact O-CB 3.47Å; K965-L969 VanDerWaalsContact O-CG 3.28Å; K965-L969 WeakPolarHBondContact O-CG 3.24Å; K965-L969 PolarHBondContact O-N 3.38Å; K966-L969 PolarHBondContact O-N 3.27Å; L969-K972 PolarHBondContact O-N 2.88Å; L969-L973 WeakPolarHBondContact O-CB 3.41Å; L969-L973 PolarHBondContact O-N 3.33Å
970Q70.1Confident68.2Low108 Ų108110.7 Ų110.751%0.50555%0.55SS.*Hα-helixtrans-68.6-44.3178.5-161149.9-5.400111.7K966 V967 Y968 K972 L973 D974K966-Q970 WeakPolarHBondContact O-CB 3.1Å; K966-Q970 PolarHBondContact O-N 3.23Å; V967-Q970 PolarHBondContact O-N 3.05Å; Y968-Q970 VanDerWaalsContact C-N 3.31Å; Y968-Q970 PolarHBondContact O-N 2.97Å; Q970-K972 VanDerWaalsContact C-N 3.27Å; Q970-K972 PolarHBondContact O-N 3.25Å; Q970-L973 WeakPolarHBondContact O-CB 3.34Å; Q970-L973 PolarHBondContact O-N 3.35Å; Q970-L973 VanDerWaalsContact O-N 3.14Å; Q970-D974 PolarHBondContact O-N 3.05Å
971R78.6Confident69Low187 Ų187107.9 Ų107.971%0.70653%0.534SS*.Hα-helixtrans-58.1-37.4170-73.7-179.8176.2178.7-0.5112.8V967 Y968 D974 S975V967-R971 WeakPolarHBondContact O-CG 3.34Å; V967-R971 PolarHBondContact O-N 2.81Å; Y968-R971 PolarHBondContact O-N 3.36Å; R971-D974 PolarHBondContact O-N 3.29Å; R971-S975 PolarHBondContact O-N 3.23Å
972K73.1Confident69.5Low116 Ų116106.1 Ų106.150%0.50453%0.531SS..Hα-helixtrans-73-31.4178.5-156.6168.2-169167.30112.4Y968 L969 Q970 K976Y968-K972 HydrophobicContact CE1-CD 3.97Å; Y968-K972 WeakPolarHBondContact O-CB 3.26Å; Y968-K972 PolarHBondContact O-N 3.17Å; Y968-K972 PolarHBondContact OH-NZ 2.96Å; Y968-K972 VanDerWaalsContact OH-NZ 3.16Å; L969-K972 PolarHBondContact O-N 2.88Å; Q970-K972 VanDerWaalsContact C-N 3.27Å; Q970-K972 PolarHBondContact O-N 3.25Å; K972-K976 PolarHBondContact O-N 3.2Å; K972-K976 VanDerWaalsContact O-N 3.14Å
973L70.9Confident69.5Low103 Ų103109.5 Ų109.554%0.53954%0.544SS..Hα-helixtrans-67.4-47.5170.6-172.572000110.8L969 Q970 S975 K976 L977L969-L973 WeakPolarHBondContact O-CB 3.41Å; L969-L973 PolarHBondContact O-N 3.33Å; Q970-L973 WeakPolarHBondContact O-CB 3.34Å; Q970-L973 PolarHBondContact O-N 3.35Å; Q970-L973 VanDerWaalsContact O-N 3.14Å; L973-S975 VanDerWaalsContact C-N 3.31Å; L973-S975 PolarHBondContact O-N 2.93Å; L973-K976 CarbonylContact O-C 3.58Å; L973-K976 PolarHBondContact O-N 3.22Å; L973-K976 VanDerWaalsContact O-N 3.13Å; L973-L977 HydrophobicContact CG-CD1 4.09Å; L973-L977 WeakPolarHBondContact O-CG 3.38Å; L973-L977 PolarHBondContact O-N 3.13Å
974D75.9Confident69.3Low83 Ų83115.1 Ų115.144%0.44455%0.553SS.*Hα-helixtrans-62.8-36.8178.2-65.9-27.4000112.2Q970 R971 L977 K978Q970-D974 PolarHBondContact O-N 3.05Å; R971-D974 PolarHBondContact O-N 3.29Å; D974-L977 PolarHBondContact O-N 3.11Å; D974-K978 WeakPolarHBondContact O-CG 3.37Å; D974-K978 PolarHBondContact O-N 2.84Å
975S75.6Confident68.7Low64 Ų64118.3 Ų118.345%0.44856%0.561SS.*Hα-helixtrans-60.3-51.2170.4-165.10000111.2R971 L973 L977 K978 D979R971-S975 PolarHBondContact O-N 3.23Å; L973-S975 VanDerWaalsContact C-N 3.31Å; L973-S975 PolarHBondContact O-N 2.93Å; S975-L977 VanDerWaalsContact C-N 3.29Å; S975-L977 PolarHBondContact O-N 3.5Å; S975-K978 WeakPolarHBondContact O-CB 3.45Å; S975-K978 PolarHBondContact O-N 2.83Å; S975-K978 VanDerWaalsContact O-N 3.13Å; S975-D979 VanDerWaalsContact O-CG 3.24Å; S975-D979 PolarHBondContact O-N 3.24Å
976K72.1Confident68.1Low147 Ų147116.8 Ų116.864%0.63957%0.567SS**Hα-helixtrans-63.3-32.2177.3-92-159.4168.9-164.70113.6K972 L973 D979 M980K972-K976 PolarHBondContact O-N 3.2Å; K972-K976 VanDerWaalsContact O-N 3.14Å; L973-K976 CarbonylContact O-C 3.58Å; L973-K976 PolarHBondContact O-N 3.22Å; L973-K976 VanDerWaalsContact O-N 3.13Å; K976-D979 PolarHBondContact O-N 3.27Å; K976-M980 WeakPolarHBondContact O-CG 3.23Å; K976-M980 PolarHBondContact O-N 3.18Å
977L73.2Confident67.6Low88 Ų88120.1 Ų120.146%0.46158%0.581SS.*Hα-helixtrans-70.2-36.3174.8-73.8169.9000111.3L973 D974 S975 M980 A981L973-L977 HydrophobicContact CG-CD1 4.09Å; L973-L977 WeakPolarHBondContact O-CG 3.38Å; L973-L977 PolarHBondContact O-N 3.13Å; D974-L977 PolarHBondContact O-N 3.11Å; S975-L977 VanDerWaalsContact C-N 3.29Å; S975-L977 PolarHBondContact O-N 3.5Å; L977-M980 HydrophobicContact CD2-CE 4Å; L977-A981 VanDerWaalsContact O-CB 3.26Å; L977-A981 WeakPolarHBondContact O-CB 3.45Å; L977-A981 PolarHBondContact O-N 2.82Å
978K74.4Confident66.3Low159 Ų159124.6 Ų124.669%0.69160%0.603SS**Hα-helixtrans-65.1-41.7169.1-76.2179.7176.2-179.10112.2D974 S975 A981 S982D974-K978 WeakPolarHBondContact O-CG 3.37Å; D974-K978 PolarHBondContact O-N 2.84Å; S975-K978 WeakPolarHBondContact O-CB 3.45Å; S975-K978 PolarHBondContact O-N 2.83Å; S975-K978 VanDerWaalsContact O-N 3.13Å; K978-A981 PolarHBondContact O-N 2.95Å; K978-A981 VanDerWaalsContact O-N 3.16Å; K978-S982 PolarHBondContact O-N 2.96Å; K978-S982 PolarHBondContact O-OG 2.85Å
979D71.6Confident64.6Low81 Ų81127.8 Ų127.843%0.43362%0.619SS.*Hα-helixtrans-65.2-38.1176.5-61.1-31.5000112.2S975 K976 S982 Q983S975-D979 VanDerWaalsContact O-CG 3.24Å; S975-D979 PolarHBondContact O-N 3.24Å; K976-D979 PolarHBondContact O-N 3.27Å; D979-S982 PolarHBondContact O-OG 2.79Å; D979-Q983 WeakPolarHBondContact O-CB 3.49Å; D979-Q983 VanDerWaalsContact O-CG 3.26Å; D979-Q983 WeakPolarHBondContact O-CG 3.17Å; D979-Q983 PolarHBondContact O-N 2.89Å; D979-Q983 VanDerWaalsContact O-N 3.1Å
980M64.8Low63.2Low96 Ų96132.8 Ų132.847%0.47364%0.64SS.*Hα-helixtrans-74-25.7172.5-71.1-160.4-55.800113.1K976 L977 R984K976-M980 WeakPolarHBondContact O-CG 3.23Å; K976-M980 PolarHBondContact O-N 3.18Å; L977-M980 HydrophobicContact CD2-CE 4Å; M980-R984 WeakPolarHBondContact O-CG 3.35Å; M980-R984 PolarHBondContact O-N 2.8Å
981A65.6Low61.7Low56 Ų56136.8 Ų136.846%0.46366%0.656SS.*Hα-helixtrans-75.2-35.8174.300000112.2L977 K978 R984L977-A981 VanDerWaalsContact O-CB 3.26Å; L977-A981 WeakPolarHBondContact O-CB 3.45Å; L977-A981 PolarHBondContact O-N 2.82Å; K978-A981 PolarHBondContact O-N 2.95Å; K978-A981 VanDerWaalsContact O-N 3.16Å; A981-R984 PolarHBondContact O-N 3.41Å
982S61.6Low59.8Low76 Ų76135 Ų13553%0.53166%0.66SS.*Hα-helixtrans-69.8-39.1172.259.80000111.6K978 D979 R984 K985K978-S982 PolarHBondContact O-N 2.96Å; K978-S982 PolarHBondContact O-OG 2.85Å; D979-S982 PolarHBondContact O-OG 2.79Å; S982-R984 PolarHBondContact O-N 3.31Å; S982-R984 VanDerWaalsContact O-N 3.16Å; S982-K985 PolarHBondContact O-N 2.79Å; S982-K985 VanDerWaalsContact O-N 3.14Å
983Q60.1Low58Low149 Ų149139.4 Ų139.470%0.69670%0.697SS**THydrogen-bonded Turntrans-63.8-14.5171.3-73.4175.71.600114.4D979D979-Q983 WeakPolarHBondContact O-CB 3.49Å; D979-Q983 VanDerWaalsContact O-CG 3.26Å; D979-Q983 WeakPolarHBondContact O-CG 3.17Å; D979-Q983 PolarHBondContact O-N 2.89Å; D979-Q983 VanDerWaalsContact O-N 3.1Å
984R55.9Low57.3Low214 Ų214141.3 Ų141.381%0.80871%0.705SS**THydrogen-bonded Turntrans-95.72175.4-76.1177.5179.5-169.90.1114.3M980 A981 S982M980-R984 WeakPolarHBondContact O-CG 3.35Å; M980-R984 PolarHBondContact O-N 2.8Å; A981-R984 PolarHBondContact O-N 3.41Å; S982-R984 PolarHBondContact O-N 3.31Å; S982-R984 VanDerWaalsContact O-N 3.16Å
985K53.1Low56.4Low192 Ų192144.3 Ų144.384%0.83572%0.719SS**SBendtrans-114.452.1177.5-77.7-167.8173.2-1750113.3S982S982-K985 PolarHBondContact O-N 2.79Å; S982-K985 VanDerWaalsContact O-N 3.14Å
986S51.8Low55.3Low96 Ų96148.8 Ų148.867%0.67173%0.734SS**SBendtrans-155.148.9171.953.70000114.3
987K50.6Low54.3Low202 Ų202148.9 Ų148.988%0.87874%0.74SS**SBendtrans-164.481.7163-112.8167.1-174.1-179.50111.4
988N44.9Very low53.1Low171 Ų171152.7 Ų152.791%0.91476%0.757SS**  trans179.573153.9-96.5-2.3000110
989K42.8Very low51.7Low204 Ų204152.3 Ų152.389%0.88776%0.762SS**  trans-15986.2158-113.6-165.1177.8-168.40106.9
990E39.6Very low50.3Low196 Ų196157.4 Ų157.492%0.91679%0.785SS**  trans175.484.5155.8-103167.2-155.800108.7
991K40.5Very low49.2Very low193 Ų193162.1 Ų162.184%0.83981%0.809SS**  trans-157.3152.2140.8-110.7-178.3-178.2-168.40108.6
992D38Very low47.8Very low148 Ų148170.9 Ų170.979%0.79184%0.838SS**  trans75.281172.7-49.4-6.4000115.5
993T34.8Very low46.6Very low210 Ų210179.5 Ų179.5100%1.28887%0.866SS**  -68.80105.550.70000109.9

Retrieved 993 of 993 residues in 397.5 ms (Link to these results)