A0A087XYG0_POEFO Loading...

Vasopressin V2 receptor

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.

AlphaFold DB , UniProt , Accession A0A087XYG0, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 497 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	30.2	Very low	24.7	Very low	217 Å²	217	161.7 Å²	161.7	100%	1.069	80%	0.804	S	S	*	*				0	136.2	0	-61.7	92.8	168.9	0	0	108.2
2	E	28.1	Very low	24.6	Very low	162 Å²	162	154.4 Å²	154.4	76%	0.757	80%	0.8	S	S	*	*			cis	-163	124.6	-24.6	-110.2	144.2	134.6	0	0	105.2
3	R	23.3	Very low	24.5	Very low	216 Å²	216	156.7 Å²	156.7	82%	0.815	81%	0.813	S	S	*	*				58.1	130.3	87.3	-112.2	-142	-74.3	-162.6	-0.7	115.6
4	I	24	Very low	24.5	Very low	141 Å²	141	150.7 Å²	150.7	72%	0.723	81%	0.809	S	S	*	*			trans	74.2	150.1	152	-78.2	173.1	0	0	0	117.4
5	S	23.7	Very low	24.4	Very low	95 Å²	95	151.9 Å²	151.9	66%	0.664	81%	0.814	S	S	*	*				-177.8	-165.6	-53	52.3	0	0	0	0	109.6
6	V	24.9	Very low	24.4	Very low	125 Å²	125	148.5 Å²	148.5	76%	0.758	81%	0.805	S	S	*	*			trans	90.5	138.3	160.1	-157.7	0	0	0	0	118.2
7	E	24.7	Very low	24.4	Very low	173 Å²	173	146.5 Å²	146.5	81%	0.808	81%	0.805	S	S	*	*			trans	-70.3	158.6	171.5	-62.8	130.4	95.1	0	0	115
8	T	25.8	Very low	24.9	Very low	135 Å²	135	145.1 Å²	145.1	83%	0.828	80%	0.804	S	S	*	*			trans	-167.5	126.4	130.7	28.5	0	0	0	0	105.7
9	D	21.1	Very low	24.8	Very low	146 Å²	146	141.2 Å²	141.2	78%	0.781	80%	0.8	S	S	*	*				94	160.2	60.3	-159.6	23.1	0	0	0	112.2
10	W	22.5	Very low	24.8	Very low	215 Å²	215	139 Å²	139	81%	0.814	80%	0.8	S	S	*	*			trans	-95.2	167.4	-141.4	-83.3	76.9	0	0	0	119.4
11	D	23.7	Very low	24.8	Very low	154 Å²	154	139 Å²	139	82%	0.824	80%	0.803	S	S	*	*			trans	72.9	138	152.3	-73	-40.4	0	0	0	122.2
12	G	23.7	Very low	25	Very low	74 Å²	74	132.3 Å²	132.3	76%	0.763	79%	0.79	S	S	*	*			trans	160.8	90.8	170.4	0	0	0	0	0	117.1
13	L	22.7	Very low	25.1	Very low	184 Å²	184	135.2 Å²	135.2	96%	0.963	79%	0.794	S	S	*	*			trans	-28.8	140.3	161.9	-51.3	162.6	0	0	0	114.7
14	G	24.5	Very low	25.5	Very low	73 Å²	73	130.7 Å²	130.7	75%	0.753	79%	0.785	S	S	*	*			cis	128.4	122	6.7	0	0	0	0	0	111.7
15	L	24	Very low	25.7	Very low	169 Å²	169	130.5 Å²	130.5	89%	0.885	79%	0.786	S	S	*	*			trans	-160.5	117.9	176.6	-110	164.4	0	0	0	115.7
16	S	23.5	Very low	26.1	Very low	97 Å²	97	131.5 Å²	131.5	68%	0.678	79%	0.788	S	S	*	*			trans	37.6	109.8	148.6	64	0	0	0	0	124.3
17	S	24.2	Very low	26.2	Very low	114 Å²	114	128.7 Å²	128.7	80%	0.797	77%	0.774	S	S	*	*				68.6	161.6	113.2	-134.8	0	0	0	0	121.6
18	P	34.6	Very low	26.3	Very low	121 Å²	121	123.7 Å²	123.7	79%	0.786	76%	0.758	S	S	*	*				-132.2	159.7	-59.4	37.3	-23.5	0	0	0	114.1
19	G	22	Very low	26.6	Very low	71 Å²	71	123.5 Å²	123.5	73%	0.732	75%	0.746	S	S	*	*			trans	159.8	126.7	155.9	0	0	0	0	0	117.9
20	A	24.6	Very low	27.1	Very low	98 Å²	98	120 Å²	120	81%	0.81	73%	0.73	S	S	*	*			trans	60.8	147	155.6	0	0	0	0	0	118.9
21	T	25.3	Very low	27.4	Very low	140 Å²	140	114.3 Å²	114.3	86%	0.859	72%	0.718	S	S	*	*			cis	-152.2	158.7	-14.4	9.2	0	0	0	0	108.9	R23	T21-R23 PolarHBondContact O-N 3.26Å
22	G	34.2	Very low	27.7	Very low	76 Å²	76	111.9 Å²	111.9	78%	0.784	70%	0.702	S	S	*	*			trans	-63.9	123.1	-165.4	0	0	0	0	0	117.3
23	R	30.1	Very low	28	Very low	223 Å²	223	111.1 Å²	111.1	84%	0.842	68%	0.681	S	S	*	*			trans	-163.1	166.1	145.3	-103.5	158.2	178	151.5	-1.3	107.8	T21	T21-R23 PolarHBondContact O-N 3.26Å
24	N	31.2	Very low	28.2	Very low	120 Å²	120	109 Å²	109	64%	0.642	67%	0.67	S	S	*	*			trans	95	-6.8	176.4	-52.1	-9.4	0	0	0	119.5	V26 S27 S28	N24-V26 PolarHBondContact O-N 3.25Å; N24-V26 VanDerWaalsContact O-N 3.15Å; N24-S27 PolarHBondContact O-N 3.05Å; N24-S27 PolarHBondContact O-OG 3.06Å; N24-S28 PolarHBondContact O-N 3.24Å
25	N	28.9	Very low	28.2	Very low	137 Å²	137	109.6 Å²	109.6	73%	0.733	66%	0.663	S	S	*	*	H	α-helix	trans	-58.3	-31.5	174.6	-69.2	42.3	0	0	0	113.3	F29	N25-F29 VanDerWaalsContact O-CB 3.27Å; N25-F29 WeakPolarHBondContact O-CB 3.41Å; N25-F29 PolarHBondContact O-N 3Å
26	V	31.6	Very low	28.3	Very low	117 Å²	117	105.3 Å²	105.3	71%	0.709	64%	0.637	S	S	*	*	H	α-helix	trans	-71.4	-40.8	179.5	-175	0	0	0	0	111.8	N24 V30	N24-V26 PolarHBondContact O-N 3.25Å; N24-V26 VanDerWaalsContact O-N 3.15Å; V26-V30 WeakPolarHBondContact O-CB 3.47Å; V26-V30 VanDerWaalsContact O-CG2 3.25Å; V26-V30 WeakPolarHBondContact O-CG2 3.26Å; V26-V30 PolarHBondContact O-N 2.85Å
27	S	27.5	Very low	28.4	Very low	65 Å²	65	106.3 Å²	106.3	46%	0.455	64%	0.635	S	S	.	*	H	α-helix	trans	-72.9	-36	176.2	44.9	0	0	0	0	112	N24 T31	N24-S27 PolarHBondContact O-N 3.05Å; N24-S27 PolarHBondContact O-OG 3.06Å; S27-T31 WeakPolarHBondContact O-CB 3.48Å; S27-T31 PolarHBondContact O-N 3.31Å; S27-T31 PolarHBondContact O-OG1 3.14Å
28	S	27.6	Very low	28.7	Very low	69 Å²	69	101.9 Å²	101.9	48%	0.483	60%	0.602	S	S	.	*	H	α-helix	trans	-57.6	-53.2	171.5	-166.9	0	0	0	0	111.2	N24 V30 T31 E32	N24-S28 PolarHBondContact O-N 3.24Å; S28-V30 PolarHBondContact O-N 3.37Å; S28-T31 PolarHBondContact O-N 3.3Å; S28-T31 VanDerWaalsContact O-N 3.11Å; S28-E32 PolarHBondContact O-N 3.08Å
29	F	31.5	Very low	28.4	Very low	131 Å²	131	98.2 Å²	98.2	58%	0.575	58%	0.579	S	S	*	*	H	α-helix	trans	-62.4	-39.5	-178.8	-172.2	-108.6	0	0	0	112.6	N25 T31 L33	N25-F29 VanDerWaalsContact O-CB 3.27Å; N25-F29 WeakPolarHBondContact O-CB 3.41Å; N25-F29 PolarHBondContact O-N 3Å; F29-T31 VanDerWaalsContact C-N 3.35Å; F29-L33 HydrophobicContact CD1-CD1 3.8Å; F29-L33 HydrophobicContact CE1-CD1 3.73Å; F29-L33 HydrophobicContact CZ-CD1 4.4Å; F29-L33 WeakPolarHBondContact O-CB 3.36Å; F29-L33 WeakPolarHBondContact O-CD1 3.49Å; F29-L33 WeakPolarHBondContact O-CG 3.44Å; F29-L33 PolarHBondContact O-N 2.98Å
30	V	30.4	Very low	29.1	Very low	73 Å²	73	99.3 Å²	99.3	44%	0.442	56%	0.561	S	S	.	*	H	α-helix	trans	-70.5	-28.3	175.4	170.4	0	0	0	0	112.6	V26 S28 N34	V26-V30 WeakPolarHBondContact O-CB 3.47Å; V26-V30 VanDerWaalsContact O-CG2 3.25Å; V26-V30 WeakPolarHBondContact O-CG2 3.26Å; V26-V30 PolarHBondContact O-N 2.85Å; S28-V30 PolarHBondContact O-N 3.37Å; V30-N34 PolarHBondContact O-ND2 3.14Å
31	T	29.3	Very low	29.2	Very low	94 Å²	94	96.8 Å²	96.8	58%	0.577	55%	0.545	S	S	*	.	H	α-helix	trans	-77	-40.8	174.7	-57.5	0	0	0	0	111.8	S27 S28 F29 L33 N34	S27-T31 WeakPolarHBondContact O-CB 3.48Å; S27-T31 PolarHBondContact O-N 3.31Å; S27-T31 PolarHBondContact O-OG1 3.14Å; S28-T31 PolarHBondContact O-N 3.3Å; S28-T31 VanDerWaalsContact O-N 3.11Å; F29-T31 VanDerWaalsContact C-N 3.35Å; T31-L33 VanDerWaalsContact C-N 3.32Å; T31-L33 PolarHBondContact O-N 3.47Å; T31-N34 PolarHBondContact O-N 3.21Å; T31-N34 VanDerWaalsContact O-N 3.13Å
32	E	30.3	Very low	29.3	Very low	104 Å²	104	92.4 Å²	92.4	49%	0.486	53%	0.527	S	S	.	.	H	α-helix	trans	-59.3	-42.8	171.2	-72.4	179.4	125.8	0	0	111.4	S28 N34 S35 F36	S28-E32 PolarHBondContact O-N 3.08Å; E32-N34 PolarHBondContact O-N 2.87Å; E32-N34 VanDerWaalsContact O-N 3.08Å; E32-S35 PolarHBondContact O-N 3.03Å; E32-S35 VanDerWaalsContact O-N 3.08Å; E32-S35 PolarHBondContact O-OG 2.82Å; E32-F36 HydrophobicContact CB-CE2 4.27Å; E32-F36 WeakPolarHBondContact O-CD2 3.28Å; E32-F36 VanDerWaalsContact O-CE2 3.27Å; E32-F36 WeakPolarHBondContact O-CE2 3.15Å
33	L	30.1	Very low	29.5	Very low	58 Å²	58	89.9 Å²	89.9	30%	0.304	50%	0.501	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.1	-21.3	175.8	-79.2	168.5	0	0	0	114.3	F29 T31 V433	F29-L33 HydrophobicContact CD1-CD1 3.8Å; F29-L33 HydrophobicContact CE1-CD1 3.73Å; F29-L33 HydrophobicContact CZ-CD1 4.4Å; F29-L33 WeakPolarHBondContact O-CB 3.36Å; F29-L33 WeakPolarHBondContact O-CD1 3.49Å; F29-L33 WeakPolarHBondContact O-CG 3.44Å; F29-L33 PolarHBondContact O-N 2.98Å; T31-L33 VanDerWaalsContact C-N 3.32Å; T31-L33 PolarHBondContact O-N 3.47Å; L33-V433 HydrophobicContact CD2-CB 4.06Å; L33-V433 HydrophobicContact CD2-CG1 3.71Å; L33-V433 HydrophobicContact CD2-CG2 4.09Å
34	N	27.3	Very low	30.2	Very low	138 Å²	138	80.5 Å²	80.5	74%	0.738	47%	0.47	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.8	-10.8	178.6	-74.8	-19.6	0	0	0	114	V30 T31 E32	V30-N34 PolarHBondContact O-ND2 3.14Å; T31-N34 PolarHBondContact O-N 3.21Å; T31-N34 VanDerWaalsContact O-N 3.13Å; E32-N34 PolarHBondContact O-N 2.87Å; E32-N34 VanDerWaalsContact O-N 3.08Å
35	S	24.1	Very low	30.8	Very low	87 Å²	87	75.3 Å²	75.3	61%	0.608	44%	0.442	S	S	*	.	T	Hydrogen-bonded Turn	trans	-99.2	-8.8	-175.1	52.8	0	0	0	0	115.4	E32 N37	E32-S35 PolarHBondContact O-N 3.03Å; E32-S35 VanDerWaalsContact O-N 3.08Å; E32-S35 PolarHBondContact O-OG 2.82Å; S35-N37 PolarHBondContact O-N 2.73Å
36	F	26.5	Very low	31.7	Very low	78 Å²	78	69 Å²	69	34%	0.342	41%	0.408	S	S	.	.			trans	-81.9	100.6	-179.2	-68.4	-71.5	0	0	0	111.8	E32 I38 V433	E32-F36 HydrophobicContact CB-CE2 4.27Å; E32-F36 WeakPolarHBondContact O-CD2 3.28Å; E32-F36 VanDerWaalsContact O-CE2 3.27Å; E32-F36 WeakPolarHBondContact O-CE2 3.15Å; F36-I38 HydrophobicContact CB-CD1 3.51Å; F36-I38 HydrophobicContact CB-CG1 3.8Å; F36-I38 WeakPolarHBondContact O-CD1 3.49Å; F36-I38 WeakPolarHBondContact O-CG1 3.41Å; F36-I38 PolarHBondContact O-N 2.68Å; F36-V433 HydrophobicContact CB-CG2 4.26Å; F36-V433 HydrophobicContact CD2-CG2 4.47Å
37	N	24.9	Very low	32.5	Very low	118 Å²	118	65 Å²	65	63%	0.631	39%	0.39	S	S	*	.			trans	-85.7	91.7	174.5	-165.8	-14.4	0	0	0	109.9	S35	S35-N37 PolarHBondContact O-N 2.73Å
38	I	31.6	Very low	33.3	Very low	21 Å²	21	62.5 Å²	62.5	11%	0.108	37%	0.371	C	S	.	.			trans	-98.1	139.3	-160.2	-70.7	153.6	0	0	0	111.5	F36 L71 Q431 V433	F36-I38 HydrophobicContact CB-CD1 3.51Å; F36-I38 HydrophobicContact CB-CG1 3.8Å; F36-I38 WeakPolarHBondContact O-CD1 3.49Å; F36-I38 WeakPolarHBondContact O-CG1 3.41Å; F36-I38 PolarHBondContact O-N 2.68Å; I38-L71 HydrophobicContact CB-CD2 4.29Å; I38-L71 HydrophobicContact CD1-CD1 3.79Å; I38-L71 HydrophobicContact CD1-CD2 3.46Å; I38-L71 VanDerWaalsContact CD1-CD2 3.46Å; I38-L71 HydrophobicContact CD1-CG 4.12Å; I38-L71 HydrophobicContact CG1-CD2 3.79Å; I38-L71 HydrophobicContact CG2-CD2 3.52Å; I38-Q431 WeakPolarHBondContact CB-O 3.39Å; I38-Q431 VanDerWaalsContact CG2-O 3.27Å; I38-Q431 WeakPolarHBondContact CG2-O 3.3Å; I38-V433 HydrophobicContact CD1-CG2 3.75Å
39	S	26.9	Very low	33.7	Very low	44 Å²	44	61.7 Å²	61.7	31%	0.308	36%	0.362	S	S	.	.			trans	-147.5	131.2	177.3	-160.8	0	0	0	0	113.5	R65	S39-R65 VanDerWaalsContact CB-CD 3.48Å; S39-R65 WeakPolarHBondContact OG-CD 3.41Å
40	R	36.9	Very low	33.9	Very low	95 Å²	95	58.2 Å²	58.2	36%	0.358	35%	0.348	S	S	.	.			trans	29.3	110.1	162.4	-74	-168.4	169.6	137.7	10.2	118.9	I50 E51	R40-I50 PolarHBondContact NH2-O 2.97Å; R40-E51 IonicContact CZ-OE1 3.52Å; R40-E51 IonicContact NE-OE1 3.81Å; R40-E51 VanDerWaalsContact NH1-CD 3.29Å; R40-E51 IonicContact NH1-OE1 2.67Å; R40-E51 PolarHBondContact NH1-OE1 3.06Å
41	G	26.4	Very low	33.9	Very low	45 Å²	45	59.9 Å²	59.9	46%	0.464	35%	0.351	S	S	.	.			trans	167.7	98.4	159	0	0	0	0	0	110	R67	G41-R67 WeakPolarHBondContact O-CD 3.38Å; G41-R67 PolarHBondContact O-NE 3.41Å; G41-R67 PolarHBondContact O-NH1 3.03Å
42	G	29	Very low	33.9	Very low	47 Å²	47	61.8 Å²	61.8	49%	0.485	36%	0.358	S	S	.	.	S	Bend	trans	137.6	154.8	-169.6	0	0	0	0	0	111.2	S44	G42-S44 PolarHBondContact O-N 3.17Å
43	G	36.8	Very low	34	Very low	23 Å²	23	60.4 Å²	60.4	24%	0.237	37%	0.371	C	S	.	.			trans	-70	132.1	-177.4	0	0	0	0	0	110	L45 Q129 D133	G43-L45 PolarHBondContact O-N 3.02Å; G43-Q129 PolarHBondContact O-NE2 2.71Å; G43-D133 PolarHBondContact N-OD1 3.5Å
44	S	45.4	Very low	33.9	Very low	27 Å²	27	63 Å²	63	19%	0.189	40%	0.395	C	S	.	.			trans	-59.1	139.5	158	161.3	0	0	0	0	108	G42 F46 G47 Q129	G42-S44 PolarHBondContact O-N 3.17Å; S44-F46 CarbonylContact O-C 3.44Å; S44-F46 PolarHBondContact O-N 3.24Å; S44-F46 PolarHBondContact OG-N 3.44Å; S44-G47 PolarHBondContact O-N 3.46Å; S44-G47 PolarHBondContact OG-N 2.99Å; S44-Q129 PolarHBondContact O-OE1 3.34Å
45	L	43	Very low	34.1	Very low	10 Å²	10	63.7 Å²	63.7	5%	0.052	40%	0.398	C	S	.	.	S	Bend	trans	-49.1	-12.4	175.6	-137.8	165.4	0	0	0	114	G43 Q125 Q129 Q152 M439 L440	G43-L45 PolarHBondContact O-N 3.02Å; L45-Q125 HydrophobicContact CD2-CG 4.03Å; L45-Q129 VanDerWaalsContact CA-OE1 3.32Å; L45-Q129 HydrophobicContact CG-CG 4.42Å; L45-Q152 PolarHBondContact O-NE2 3.02Å; L45-M439 HydrophobicContact CB-CE 4.18Å; L45-M439 HydrophobicContact CD1-CB 4.38Å; L45-L440 HydrophobicContact CD1-CD2 3.96Å; L45-L440 HydrophobicContact CD1-CG 4.4Å
46	F	49.4	Very low	34.5	Very low	6 Å²	6	65.7 Å²	65.7	3%	0.026	41%	0.407	C	S	.	.	S	Bend	trans	-126.8	-13.9	164.8	-98.7	-78	0	0	0	117.4	S44 I48 K149 Q152 I153 M156 F415	S44-F46 CarbonylContact O-C 3.44Å; S44-F46 PolarHBondContact O-N 3.24Å; S44-F46 PolarHBondContact OG-N 3.44Å; F46-I48 HydrophobicContact CB-CB 4.36Å; F46-I48 HydrophobicContact CB-CD1 3.57Å; F46-I48 HydrophobicContact CB-CG1 3.84Å; F46-I48 HydrophobicContact CD1-CD1 4.46Å; F46-I48 HydrophobicContact CG-CD1 4.13Å; F46-K149 PolarHBondContact O-NZ 2.9Å; F46-Q152 HydrophobicContact CD1-CG 4.4Å; F46-Q152 HydrophobicContact CE1-CG 3.63Å; F46-Q152 VanDerWaalsContact CE1-NE2 3.3Å; F46-Q152 HydrophobicContact CZ-CG 3.95Å; F46-I153 HydrophobicContact CD1-CD1 3.97Å; F46-I153 HydrophobicContact CE1-CD1 3.26Å; F46-I153 HydrophobicContact CE1-CG1 3.8Å; F46-I153 HydrophobicContact CZ-CD1 4.04Å; F46-M156 HydrophobicContact CE2-CE 3.44Å; F46-M156 VanDerWaalsContact CE2-CE 3.44Å; F46-M156 HydrophobicContact CE2-SD 3.74Å; F46-M156 HydrophobicContact CZ-CE 3.37Å; F46-M156 HydrophobicContact CZ-SD 3.49Å; F46-M156 WeakPolarHBondContact CZ-SD 3.25Å; F46-F415 HydrophobicContact CD2-CE1 4.47Å; F46-F415 AromaticContact CD2-CE2 3.89Å; F46-F415 HydrophobicContact CD2-CE2 3.89Å; F46-F415 AromaticContact CD2-CZ 3.41Å; F46-F415 HydrophobicContact CD2-CZ 3.41Å; F46-F415 VanDerWaalsContact CD2-CZ 3.41Å; F46-F415 HydrophobicContact CE2-CE1 4.47Å; F46-F415 HydrophobicContact CE2-CE2 4.37Å; F46-F415 AromaticContact CE2-CZ 3.74Å; F46-F415 HydrophobicContact CE2-CZ 3.74Å; F46-F415 HydrophobicContact CG-CZ 4.4Å
47	G	47.9	Very low	34.5	Very low	31 Å²	31	69 Å²	69	32%	0.32	43%	0.433	S	S	.	.	S	Bend	trans	71	44.1	-168.6	0	0	0	0	0	112.3	S44	S44-G47 PolarHBondContact O-N 3.46Å; S44-G47 PolarHBondContact OG-N 2.99Å
48	I	44.5	Very low	35.1	Very low	13 Å²	13	67.4 Å²	67.4	7%	0.067	44%	0.437	C	S	.	.			trans	-108.7	-16.4	-174.6	-79.2	174.8	0	0	0	113.3	F46 I50 L233 Y236 V237	F46-I48 HydrophobicContact CB-CB 4.36Å; F46-I48 HydrophobicContact CB-CD1 3.57Å; F46-I48 HydrophobicContact CB-CG1 3.84Å; F46-I48 HydrophobicContact CD1-CD1 4.46Å; F46-I48 HydrophobicContact CG-CD1 4.13Å; I48-I50 PolarHBondContact O-N 3.22Å; I48-L233 HydrophobicContact CG2-CD1 4.32Å; I48-Y236 HydrophobicContact CD1-CD1 4.44Å; I48-Y236 HydrophobicContact CD1-CE1 3.64Å; I48-Y236 HydrophobicContact CG1-CE1 3.87Å; I48-V237 HydrophobicContact CD1-CG2 4.46Å; I48-V237 HydrophobicContact CG2-CG2 3.63Å
49	L	36.3	Very low	35.4	Very low	53 Å²	53	75.3 Å²	75.3	28%	0.277	47%	0.473	S	S	.	.			trans	-78	105.3	177.3	-102.4	166.2	0	0	0	110.8	F435	L49-F435 HydrophobicContact CD1-CE1 4.01Å; L49-F435 HydrophobicContact CD1-CZ 3.86Å
50	I	34.8	Very low	35.5	Very low	58 Å²	58	79.6 Å²	79.6	30%	0.297	50%	0.497	S	S	.	.			trans	-74.4	144.5	175.1	-70.6	-170.8	0	0	0	111.2	R40 I48 F227 L233	R40-I50 PolarHBondContact NH2-O 2.97Å; I48-I50 PolarHBondContact O-N 3.22Å; I50-F227 HydrophobicContact CD1-CD2 4.02Å; I50-L233 HydrophobicContact CD1-CB 4.16Å; I50-L233 HydrophobicContact CD1-CD1 4.17Å; I50-L233 HydrophobicContact CD1-CD2 3.85Å; I50-L233 HydrophobicContact CD1-CG 4.27Å; I50-L233 HydrophobicContact CG1-CD1 4.35Å; I50-L233 HydrophobicContact CG1-CD2 4.02Å
51	E	31.1	Very low	35.1	Very low	108 Å²	108	81.1 Å²	81.1	51%	0.505	52%	0.517	S	S	.	.			trans	-93.6	109.2	163	-178.3	135.4	-123.7	0	0	109.8	R40 G53	R40-E51 IonicContact CZ-OE1 3.52Å; R40-E51 IonicContact NE-OE1 3.81Å; R40-E51 VanDerWaalsContact NH1-CD 3.29Å; R40-E51 IonicContact NH1-OE1 2.67Å; R40-E51 PolarHBondContact NH1-OE1 3.06Å; E51-G53 PolarHBondContact O-N 3.07Å
52	N	29.5	Very low	35.2	Very low	134 Å²	134	84.4 Å²	84.4	72%	0.717	53%	0.53	S	S	*	.			trans	-70.2	99.6	177.4	-78	-9.2	0	0	0	110.5	S54	N52-S54 PolarHBondContact O-N 3.1Å
53	G	31.6	Very low	35.1	Very low	74 Å²	74	90.2 Å²	90.2	76%	0.763	55%	0.545	S	S	*	.			trans	-75.2	96.8	167.8	0	0	0	0	0	111.3	E51	E51-G53 PolarHBondContact O-N 3.07Å
54	S	28.3	Very low	34.9	Very low	114 Å²	114	94.2 Å²	94.2	80%	0.797	57%	0.567	S	S	*	*			trans	-85.8	135.8	171.2	60.4	0	0	0	0	111.3	N52	N52-S54 PolarHBondContact O-N 3.1Å
55	N	32.1	Very low	34.5	Very low	152 Å²	152	100.7 Å²	100.7	81%	0.813	59%	0.587	S	S	*	*			trans	-80.6	127.5	-175.7	-80.4	-41.9	0	0	0	112.8
56	T	31.7	Very low	34.6	Very low	129 Å²	129	106.3 Å²	106.3	79%	0.791	62%	0.621	S	S	*	*			trans	56.9	111.9	156	48.5	0	0	0	0	119.6
57	T	26.4	Very low	34.6	Very low	146 Å²	146	109.1 Å²	109.1	90%	0.896	63%	0.632	S	S	*	*				-144.3	159	103.1	22.1	0	0	0	0	109.8
58	A	38.4	Very low	35.4	Very low	85 Å²	85	110.3 Å²	110.3	70%	0.702	63%	0.631	S	S	*	*			trans	-84.3	164.4	-174	0	0	0	0	0	113.7
59	H	36.5	Very low	36.4	Very low	187 Å²	187	113.2 Å²	113.2	87%	0.866	65%	0.65	S	S	*	*	S	Bend	trans	73.9	51.3	172.5	-63.5	-77.4	0	0	0	118.6
60	T	28.5	Very low	38.1	Very low	134 Å²	134	112.9 Å²	112.9	82%	0.822	66%	0.66	S	S	*	*			trans	-143.9	134.2	133.3	-32.1	0	0	0	0	109.6	P62	T60-P62 WeakPolarHBondContact O-CD 3.46Å
61	V	29.3	Very low	39.6	Very low	127 Å²	127	111.3 Å²	111.3	77%	0.77	65%	0.652	S	S	*	*	P	Polyproline II helix	trans	-75.6	124.2	170.5	177.2	0	0	0	0	107.6	Q63	V61-Q63 PolarHBondContact O-N 3.36Å
62	P	29.7	Very low	41.4	Very low	114 Å²	114	106.8 Å²	106.8	74%	0.74	63%	0.633	S	S	*	*	P	Polyproline II helix	trans	-62.1	122.6	173.4	-21.1	33.5	0	0	0	109.8	T60	T60-P62 WeakPolarHBondContact O-CD 3.46Å
63	Q	25.4	Very low	43.7	Very low	169 Å²	169	109.1 Å²	109.1	79%	0.79	63%	0.632	S	S	*	*	P	Polyproline II helix	trans	-60.9	130.8	171.5	-78.8	-73.6	8.7	0	0	109.3	V61 R65	V61-Q63 PolarHBondContact O-N 3.36Å; Q63-R65 PolarHBondContact O-N 2.85Å; Q63-R65 VanDerWaalsContact O-N 3.11Å
64	P	32.6	Very low	45.8	Very low	108 Å²	108	107.8 Å²	107.8	70%	0.701	61%	0.614	S	S	*	*	P	Polyproline II helix	trans	-59.8	116.8	172.3	-21.1	32.7	0	0	0	109.4	V66	P64-V66 PolarHBondContact O-N 2.96Å
65	R	37.8	Very low	48	Very low	162 Å²	162	104 Å²	104	61%	0.611	58%	0.584	S	S	*	*	P	Polyproline II helix	trans	-67.6	122.6	176.8	-63.1	-164.7	-176.1	98.3	-7.7	108.7	S39 Q63 R67	S39-R65 VanDerWaalsContact CB-CD 3.48Å; S39-R65 WeakPolarHBondContact OG-CD 3.41Å; Q63-R65 PolarHBondContact O-N 2.85Å; Q63-R65 VanDerWaalsContact O-N 3.11Å; R65-R67 PolarHBondContact O-N 3.47Å
66	V	43.8	Very low	50.4	Low	128 Å²	128	99 Å²	99	78%	0.776	56%	0.556	S	S	*	*	P	Polyproline II helix	trans	-77.3	117.9	-178	179.2	0	0	0	0	109	P64 D68	P64-V66 PolarHBondContact O-N 2.96Å; V66-D68 PolarHBondContact O-N 3.36Å
67	R	51.1	Low	52.9	Low	65 Å²	65	95.7 Å²	95.7	25%	0.245	54%	0.541	C	S	.	.			trans	-68.9	115.2	174.5	176.9	149	103	127.6	2.4	109.8	G41 R65 P69 A72 D133 E136	G41-R67 WeakPolarHBondContact O-CD 3.38Å; G41-R67 PolarHBondContact O-NE 3.41Å; G41-R67 PolarHBondContact O-NH1 3.03Å; R65-R67 PolarHBondContact O-N 3.47Å; R67-P69 VanDerWaalsContact O-CD 3.27Å; R67-P69 WeakPolarHBondContact O-CD 3.2Å; R67-P69 VanDerWaalsContact O-N 3.1Å; R67-A72 HydrophobicContact CG-CB 4.42Å; R67-D133 PolarHBondContact NH2-O 3.44Å; R67-E136 IonicContact CZ-OE1 3.24Å; R67-E136 VanDerWaalsContact CZ-OE1 3.24Å; R67-E136 IonicContact NE-OE1 3.1Å; R67-E136 PolarHBondContact NE-OE1 3.32Å; R67-E136 VanDerWaalsContact NE-OE1 3.1Å; R67-E136 IonicContact NH2-OE1 2.68Å; R67-E136 PolarHBondContact NH2-OE1 2.97Å
68	D	63.2	Low	55.6	Low	56 Å²	56	92.4 Å²	92.4	30%	0.299	52%	0.518	S	S	.	.			trans	-57.9	111.7	179.3	-92.3	-41.3	0	0	0	111.3	V66 G70 L71 A72	V66-D68 PolarHBondContact O-N 3.36Å; D68-G70 PolarHBondContact O-N 3.39Å; D68-L71 HydrophobicContact CB-CB 4.22Å; D68-L71 PolarHBondContact O-N 3.14Å; D68-A72 PolarHBondContact O-N 3.33Å
69	P	67.4	Low	57.6	Low	74 Å²	74	88.4 Å²	88.4	48%	0.481	49%	0.485	S	S	.	.	H	α-helix	trans	-71.6	-18.5	-172.3	28.9	-35.3	0	0	0	112.5	R67 R73	R67-P69 VanDerWaalsContact O-CD 3.27Å; R67-P69 WeakPolarHBondContact O-CD 3.2Å; R67-P69 VanDerWaalsContact O-N 3.1Å; P69-R73 WeakPolarHBondContact O-CD 3.46Å; P69-R73 WeakPolarHBondContact O-CG 3.38Å; P69-R73 PolarHBondContact O-NE 3.31Å
70	G	71.8	Confident	60.1	Low	46 Å²	46	80.8 Å²	80.8	47%	0.474	46%	0.456	S	S	.	.	H	α-helix	trans	-69.4	-45.6	171.7	0	0	0	0	0	112.3	D68 A74	D68-G70 PolarHBondContact O-N 3.39Å; G70-A74 PolarHBondContact O-N 3.45Å; G70-A74 VanDerWaalsContact O-N 3.15Å
71	L	66.3	Low	62.9	Low	25 Å²	25	78.4 Å²	78.4	13%	0.131	44%	0.442	C	S	.	.	H	α-helix	trans	-66.9	-50.6	-179.5	-175.3	78.9	0	0	0	111.7	I38 D68 R73 A74 E75 V433	I38-L71 HydrophobicContact CB-CD2 4.29Å; I38-L71 HydrophobicContact CD1-CD1 3.79Å; I38-L71 HydrophobicContact CD1-CD2 3.46Å; I38-L71 VanDerWaalsContact CD1-CD2 3.46Å; I38-L71 HydrophobicContact CD1-CG 4.12Å; I38-L71 HydrophobicContact CG1-CD2 3.79Å; I38-L71 HydrophobicContact CG2-CD2 3.52Å; D68-L71 HydrophobicContact CB-CB 4.22Å; D68-L71 PolarHBondContact O-N 3.14Å; L71-R73 PolarHBondContact O-N 3Å; L71-A74 CarbonylContact O-C 3.59Å; L71-A74 WeakPolarHBondContact O-CA 3.4Å; L71-A74 WeakPolarHBondContact O-CB 3.44Å; L71-A74 PolarHBondContact O-N 2.88Å; L71-E75 PolarHBondContact O-N 3.5Å; L71-V433 HydrophobicContact CD1-CB 4.35Å; L71-V433 HydrophobicContact CD1-CG1 3.93Å; L71-V433 HydrophobicContact CD1-CG2 3.93Å
72	A	67.4	Low	65.7	Low	13 Å²	13	72.7 Å²	72.7	11%	0.107	41%	0.407	C	S	.	.	H	α-helix	trans	-57	-38.3	-177.7	0	0	0	0	0	111.4	R67 D68 I76	R67-A72 HydrophobicContact CG-CB 4.42Å; D68-A72 PolarHBondContact O-N 3.33Å; A72-I76 VanDerWaalsContact O-CB 3.31Å; A72-I76 WeakPolarHBondContact O-CB 3.39Å; A72-I76 WeakPolarHBondContact O-CD1 3.43Å; A72-I76 WeakPolarHBondContact O-CG1 3.36Å; A72-I76 PolarHBondContact O-N 3.17Å
73	R	77.5	Confident	68.6	Low	183 Å²	183	68.5 Å²	68.5	69%	0.691	38%	0.378	S	S	*	.	H	α-helix	trans	-64.9	-39.4	172.9	-70.4	170.5	-170.6	175	2.8	112.8	P69 L71 A77	P69-R73 WeakPolarHBondContact O-CD 3.46Å; P69-R73 WeakPolarHBondContact O-CG 3.38Å; P69-R73 PolarHBondContact O-NE 3.31Å; L71-R73 PolarHBondContact O-N 3Å; R73-A77 WeakPolarHBondContact O-CB 3.27Å; R73-A77 PolarHBondContact O-N 3.28Å
74	A	77.1	Confident	71.8	Confident	46 Å²	46	62.5 Å²	62.5	38%	0.38	36%	0.357	S	S	.	.	H	α-helix	trans	-67.7	-43.8	177.3	0	0	0	0	0	112	G70 L71 A77 I78	G70-A74 PolarHBondContact O-N 3.45Å; G70-A74 VanDerWaalsContact O-N 3.15Å; L71-A74 CarbonylContact O-C 3.59Å; L71-A74 WeakPolarHBondContact O-CA 3.4Å; L71-A74 WeakPolarHBondContact O-CB 3.44Å; L71-A74 PolarHBondContact O-N 2.88Å; A74-A77 PolarHBondContact O-N 3.36Å; A74-I78 WeakPolarHBondContact O-CD1 3.27Å; A74-I78 VanDerWaalsContact O-CG1 3.23Å; A74-I78 WeakPolarHBondContact O-CG1 3.38Å; A74-I78 PolarHBondContact O-N 2.82Å
75	E	74.1	Confident	74.6	Confident	36 Å²	36	61.7 Å²	61.7	17%	0.168	35%	0.347	C	S	.	.	H	α-helix	trans	-62.6	-50	176.8	-179.4	160.3	-142.9	0	0	111.7	L71 A77 I78 L79 T436	L71-E75 PolarHBondContact O-N 3.5Å; E75-A77 VanDerWaalsContact C-N 3.29Å; E75-A77 PolarHBondContact O-N 2.92Å; E75-I78 PolarHBondContact O-N 2.92Å; E75-L79 HydrophobicContact CG-CD1 3.91Å; E75-L79 WeakPolarHBondContact O-CB 3.33Å; E75-L79 WeakPolarHBondContact O-CG 3.33Å; E75-L79 PolarHBondContact O-N 3.24Å; E75-T436 HydrophobicContact CG-CG2 4.16Å; E75-T436 WeakPolarHBondContact OE1-CG2 3.44Å
76	I	81.7	Confident	77.1	Confident	47 Å²	47	54 Å²	54	24%	0.241	32%	0.318	C	S	.	.	H	α-helix	trans	-56.9	-42	174.2	-70.7	166.2	0	0	0	111.2	A72 G80 L130 D133 I134	A72-I76 VanDerWaalsContact O-CB 3.31Å; A72-I76 WeakPolarHBondContact O-CB 3.39Å; A72-I76 WeakPolarHBondContact O-CD1 3.43Å; A72-I76 WeakPolarHBondContact O-CG1 3.36Å; A72-I76 PolarHBondContact O-N 3.17Å; I76-G80 PolarHBondContact O-N 2.92Å; I76-L130 HydrophobicContact CB-CD1 4.4Å; I76-L130 HydrophobicContact CG2-CD1 3.9Å; I76-L130 WeakPolarHBondContact O-CD1 3.33Å; I76-D133 HydrophobicContact CG1-CB 4.04Å; I76-I134 HydrophobicContact CD1-CG1 3.93Å; I76-I134 HydrophobicContact CG1-CG1 4.15Å; I76-I134 HydrophobicContact CG2-CD1 4.1Å; I76-I134 HydrophobicContact CG2-CG1 4Å
77	A	84.6	Confident	79.4	Confident	58 Å²	58	49.6 Å²	49.6	48%	0.479	29%	0.291	S	S	.	.	H	α-helix	trans	-66.6	-43	177.6	0	0	0	0	0	112.6	R73 A74 E75 G80 V81	R73-A77 WeakPolarHBondContact O-CB 3.27Å; R73-A77 PolarHBondContact O-N 3.28Å; A74-A77 PolarHBondContact O-N 3.36Å; E75-A77 VanDerWaalsContact C-N 3.29Å; E75-A77 PolarHBondContact O-N 2.92Å; A77-G80 PolarHBondContact O-N 3.28Å; A77-V81 WeakPolarHBondContact O-CG2 3.35Å; A77-V81 PolarHBondContact O-N 2.93Å
78	I	82.4	Confident	81.4	Confident	78 Å²	78	52.5 Å²	52.5	40%	0.4	31%	0.311	S	S	.	.	H	α-helix	trans	-66	-46	177.9	-66.2	160.9	0	0	0	110.4	A74 E75 G80 V81 V82 L440	A74-I78 WeakPolarHBondContact O-CD1 3.27Å; A74-I78 VanDerWaalsContact O-CG1 3.23Å; A74-I78 WeakPolarHBondContact O-CG1 3.38Å; A74-I78 PolarHBondContact O-N 2.82Å; E75-I78 PolarHBondContact O-N 2.92Å; I78-G80 VanDerWaalsContact C-N 3.34Å; I78-G80 PolarHBondContact O-N 3.35Å; I78-V81 PolarHBondContact O-N 3.09Å; I78-V82 HydrophobicContact CG2-CG2 4.3Å; I78-V82 WeakPolarHBondContact O-CB 3.47Å; I78-V82 VanDerWaalsContact O-CG2 3.3Å; I78-V82 WeakPolarHBondContact O-CG2 3.36Å; I78-V82 PolarHBondContact O-N 3.16Å; I78-L440 HydrophobicContact CB-CD1 4.49Å; I78-L440 HydrophobicContact CG2-CD1 3.94Å
79	L	81.1	Confident	82.7	Confident	1 Å²	1	50.8 Å²	50.8	1%	0.005	31%	0.306	C	S	.	.	H	α-helix	trans	-59.8	-42.6	175.4	-76.3	167	0	0	0	111.9	E75 V82 L83 V126 Q129 L130 D133 L440	E75-L79 HydrophobicContact CG-CD1 3.91Å; E75-L79 WeakPolarHBondContact O-CB 3.33Å; E75-L79 WeakPolarHBondContact O-CG 3.33Å; E75-L79 PolarHBondContact O-N 3.24Å; L79-V82 PolarHBondContact O-N 2.97Å; L79-L83 VanDerWaalsContact O-CB 3.28Å; L79-L83 WeakPolarHBondContact O-CB 3.33Å; L79-L83 PolarHBondContact O-N 3.46Å; L79-V126 HydrophobicContact CD2-CG1 4.31Å; L79-Q129 HydrophobicContact CD1-CG 3.89Å; L79-Q129 HydrophobicContact CD2-CG 4.08Å; L79-L130 HydrophobicContact CB-CB 4.47Å; L79-L130 HydrophobicContact CB-CD1 3.97Å; L79-D133 WeakPolarHBondContact CD1-OD2 3.42Å; L79-L440 HydrophobicContact CD2-CD2 3.53Å; L79-L440 HydrophobicContact CG-CD2 3.93Å
80	G	88.6	Confident	83.9	Confident	26 Å²	26	47.2 Å²	47.2	27%	0.268	28%	0.283	S	S	.	.	H	α-helix	trans	-61	-42.9	174.6	0	0	0	0	0	113.2	I76 A77 I78 A84	I76-G80 PolarHBondContact O-N 2.92Å; A77-G80 PolarHBondContact O-N 3.28Å; I78-G80 VanDerWaalsContact C-N 3.34Å; I78-G80 PolarHBondContact O-N 3.35Å; G80-A84 WeakPolarHBondContact O-CB 3.21Å; G80-A84 PolarHBondContact O-N 2.85Å
81	V	89	Confident	84.8	Confident	85 Å²	85	47.7 Å²	47.7	52%	0.515	28%	0.279	S	S	.	.	H	α-helix	trans	-66.8	-43.9	175.4	170.1	0	0	0	0	111.4	A77 I78 L83 A84 L85	A77-V81 WeakPolarHBondContact O-CG2 3.35Å; A77-V81 PolarHBondContact O-N 2.93Å; I78-V81 PolarHBondContact O-N 3.09Å; V81-L83 VanDerWaalsContact C-N 3.35Å; V81-L83 PolarHBondContact O-N 3.23Å; V81-A84 PolarHBondContact O-N 2.79Å; V81-L85 HydrophobicContact CG1-CD1 3.82Å; V81-L85 HydrophobicContact CG1-CG 4.28Å; V81-L85 WeakPolarHBondContact O-CB 3.34Å; V81-L85 VanDerWaalsContact O-CG 3.3Å; V81-L85 WeakPolarHBondContact O-CG 3.48Å; V81-L85 PolarHBondContact O-N 3.49Å
82	V	87.1	Confident	85.9	Confident	7 Å²	7	50.5 Å²	50.5	4%	0.042	29%	0.29	C	S	.	.	H	α-helix	trans	-60.9	-43	176.1	164.9	0	0	0	0	111.2	I78 L79 T86 V126 L444	I78-V82 HydrophobicContact CG2-CG2 4.3Å; I78-V82 WeakPolarHBondContact O-CB 3.47Å; I78-V82 VanDerWaalsContact O-CG2 3.3Å; I78-V82 WeakPolarHBondContact O-CG2 3.36Å; I78-V82 PolarHBondContact O-N 3.16Å; L79-V82 PolarHBondContact O-N 2.97Å; V82-T86 WeakPolarHBondContact O-CB 3.42Å; V82-T86 PolarHBondContact O-N 2.93Å; V82-T86 PolarHBondContact O-OG1 3.45Å; V82-V126 HydrophobicContact CG1-CG1 4.18Å; V82-L444 HydrophobicContact CG2-CD2 4.16Å
83	L	90.4	Very high	86.9	Confident	25 Å²	25	50 Å²	50	13%	0.131	29%	0.286	C	S	.	.	H	α-helix	trans	-61.8	-48.3	175.2	-179.2	62.8	0	0	0	111.3	L79 V81 T86 T87 A122 V126 L127 L130	L79-L83 VanDerWaalsContact O-CB 3.28Å; L79-L83 WeakPolarHBondContact O-CB 3.33Å; L79-L83 PolarHBondContact O-N 3.46Å; V81-L83 VanDerWaalsContact C-N 3.35Å; V81-L83 PolarHBondContact O-N 3.23Å; L83-T86 PolarHBondContact O-N 2.84Å; L83-T87 HydrophobicContact CD1-CG2 3.92Å; L83-T87 HydrophobicContact CG-CG2 4.48Å; L83-T87 WeakPolarHBondContact O-CB 3.42Å; L83-T87 WeakPolarHBondContact O-CG2 3.3Å; L83-T87 PolarHBondContact O-N 3.01Å; L83-T87 PolarHBondContact O-OG1 3.37Å; L83-A122 HydrophobicContact CD1-CB 4.19Å; L83-A122 VanDerWaalsContact CD1-O 3.29Å; L83-A122 WeakPolarHBondContact CD1-O 3.43Å; L83-V126 HydrophobicContact CB-CG1 3.87Å; L83-V126 HydrophobicContact CD1-CB 4.19Å; L83-V126 HydrophobicContact CD1-CG1 4.27Å; L83-L127 HydrophobicContact CD1-CB 4.06Å; L83-L127 HydrophobicContact CD2-CB 4.22Å; L83-L127 HydrophobicContact CD2-CD1 4.02Å; L83-L130 HydrophobicContact CD2-CD2 3.74Å
84	A	92.6	Very high	87.5	Confident	43 Å²	43	42.6 Å²	42.6	36%	0.355	26%	0.26	S	S	.	.	H	α-helix	trans	-62.1	-46.2	178.9	0	0	0	0	0	112.1	G80 V81 T87 L88	G80-A84 WeakPolarHBondContact O-CB 3.21Å; G80-A84 PolarHBondContact O-N 2.85Å; V81-A84 PolarHBondContact O-N 2.79Å; A84-T87 PolarHBondContact O-OG1 3.36Å; A84-L88 VanDerWaalsContact O-CB 3.22Å; A84-L88 WeakPolarHBondContact O-CB 3.38Å; A84-L88 WeakPolarHBondContact O-CG 3.47Å; A84-L88 PolarHBondContact O-N 3.06Å
85	L	90.9	Very high	88	Confident	92 Å²	92	46.4 Å²	46.4	48%	0.482	27%	0.265	S	S	.	.	H	α-helix	trans	-64	-44.1	177.8	-70.6	174.5	0	0	0	112.1	V81 G89	V81-L85 HydrophobicContact CG1-CD1 3.82Å; V81-L85 HydrophobicContact CG1-CG 4.28Å; V81-L85 WeakPolarHBondContact O-CB 3.34Å; V81-L85 VanDerWaalsContact O-CG 3.3Å; V81-L85 WeakPolarHBondContact O-CG 3.48Å; V81-L85 PolarHBondContact O-N 3.49Å; L85-G89 WeakPolarHBondContact O-CA 3.48Å; L85-G89 PolarHBondContact O-N 2.99Å
86	T	90.3	Very high	88.5	Confident	1 Å²	1	45.2 Å²	45.2	1%	0.006	26%	0.26	C	S	.	.	H	α-helix	trans	-67	-47	-179.4	-51.9	0	0	0	0	111.4	V82 L83 N90 A122 C447	V82-T86 WeakPolarHBondContact O-CB 3.42Å; V82-T86 PolarHBondContact O-N 2.93Å; V82-T86 PolarHBondContact O-OG1 3.45Å; L83-T86 PolarHBondContact O-N 2.84Å; T86-N90 WeakPolarHBondContact O-CB 3.4Å; T86-N90 PolarHBondContact O-N 3.2Å; T86-N90 VanDerWaalsContact O-N 3.1Å; T86-N90 PolarHBondContact O-ND2 3.32Å; T86-N90 VanDerWaalsContact O-ND2 3.09Å; T86-A122 HydrophobicContact CG2-CB 3.9Å; T86-C447 PolarHBondContact OG1-SG 3.14Å
87	T	92.9	Very high	88.5	Confident	34 Å²	34	43.5 Å²	43.5	21%	0.209	25%	0.251	C	S	.	.	H	α-helix	trans	-67.4	-52.7	-178.9	52.2	0	0	0	0	112.2	L83 A84 S91 A122	L83-T87 HydrophobicContact CD1-CG2 3.92Å; L83-T87 HydrophobicContact CG-CG2 4.48Å; L83-T87 WeakPolarHBondContact O-CB 3.42Å; L83-T87 WeakPolarHBondContact O-CG2 3.3Å; L83-T87 PolarHBondContact O-N 3.01Å; L83-T87 PolarHBondContact O-OG1 3.37Å; A84-T87 PolarHBondContact O-OG1 3.36Å; T87-S91 WeakPolarHBondContact O-CB 3.28Å; T87-S91 PolarHBondContact O-N 3.49Å; T87-S91 PolarHBondContact O-OG 2.97Å; T87-A122 HydrophobicContact CG2-CB 3.68Å
88	L	93	Very high	88.5	Confident	126 Å²	126	46.1 Å²	46.1	66%	0.66	26%	0.257	S	S	*	.	H	α-helix	trans	-66.6	-44	-178.4	-63	173	0	0	0	111.5	A84 F92	A84-L88 VanDerWaalsContact O-CB 3.22Å; A84-L88 WeakPolarHBondContact O-CB 3.38Å; A84-L88 WeakPolarHBondContact O-CG 3.47Å; A84-L88 PolarHBondContact O-N 3.06Å; L88-F92 VanDerWaalsContact O-CB 3.24Å; L88-F92 WeakPolarHBondContact O-CB 3.26Å; L88-F92 PolarHBondContact O-N 3.47Å
89	G	90.5	Very high	88.5	Confident	20 Å²	20	50.5 Å²	50.5	21%	0.206	27%	0.268	C	S	.	.	H	α-helix	trans	-62.4	-52.6	-179.8	0	0	0	0	0	112.8	L85 F92 V93	L85-G89 WeakPolarHBondContact O-CA 3.48Å; L85-G89 PolarHBondContact O-N 2.99Å; G89-F92 PolarHBondContact O-N 3.49Å; G89-V93 WeakPolarHBondContact O-CG2 3.34Å; G89-V93 PolarHBondContact O-N 2.72Å; G89-V93 VanDerWaalsContact O-N 3.09Å
90	N	92.1	Very high	88	Confident	0 Å²	0	56.6 Å²	56.6	0%	0	29%	0.291	C	S	.	.	H	α-helix	trans	-72.5	-34.2	-179.6	-72.7	-66.7	0	0	0	112.4	T86 V93 L94 C115 L119 S446	T86-N90 WeakPolarHBondContact O-CB 3.4Å; T86-N90 PolarHBondContact O-N 3.2Å; T86-N90 VanDerWaalsContact O-N 3.1Å; T86-N90 PolarHBondContact O-ND2 3.32Å; T86-N90 VanDerWaalsContact O-ND2 3.09Å; N90-V93 PolarHBondContact O-N 3.43Å; N90-L94 WeakPolarHBondContact O-CB 3.32Å; N90-L94 PolarHBondContact O-N 3.05Å; N90-C115 HydrophobicContact CB-CB 4.19Å; N90-C115 PolarHBondContact OD1-SG 2.96Å; N90-L119 HydrophobicContact CB-CD2 4.25Å; N90-L119 HydrophobicContact CB-CG 4.06Å; N90-S446 PolarHBondContact ND2-O 3.28Å; N90-S446 VanDerWaalsContact ND2-O 3.12Å
91	S	91.9	Very high	86.8	Confident	55 Å²	55	66.9 Å²	66.9	39%	0.385	32%	0.322	S	S	.	.	H	α-helix	trans	-64.3	-42	173.8	-60.1	0	0	0	0	112.3	T87 W95	T87-S91 WeakPolarHBondContact O-CB 3.28Å; T87-S91 PolarHBondContact O-N 3.49Å; T87-S91 PolarHBondContact O-OG 2.97Å; S91-W95 WeakPolarHBondContact O-CB 3.45Å; S91-W95 PolarHBondContact O-N 2.73Å
92	F	89.3	Confident	85.5	Confident	84 Å²	84	72 Å²	72	37%	0.368	34%	0.337	S	S	.	.	H	α-helix	trans	-63.7	-48.3	176.6	175.9	-97.4	0	0	0	111.7	L88 G89 W95 V96 L464 L467	L88-F92 VanDerWaalsContact O-CB 3.24Å; L88-F92 WeakPolarHBondContact O-CB 3.26Å; L88-F92 PolarHBondContact O-N 3.47Å; G89-F92 PolarHBondContact O-N 3.49Å; F92-W95 PolarHBondContact O-N 3.1Å; F92-V96 HydrophobicContact CD1-CG2 4.44Å; F92-V96 HydrophobicContact CE1-CG2 3.98Å; F92-V96 HydrophobicContact CE2-CG2 4.26Å; F92-V96 HydrophobicContact CZ-CG2 3.89Å; F92-V96 WeakPolarHBondContact O-CG2 3.28Å; F92-V96 PolarHBondContact O-N 2.91Å; F92-L464 HydrophobicContact CE1-CD1 4.02Å; F92-L464 HydrophobicContact CZ-CD1 3.95Å; F92-L467 HydrophobicContact CZ-CD1 4.29Å
93	V	87.6	Confident	83.9	Confident	3 Å²	3	78.7 Å²	78.7	2%	0.018	37%	0.368	C	S	.	.	H	α-helix	trans	-62.8	-44.3	177.6	172.7	0	0	0	0	111.1	G89 N90 W95 V96 L97 P450 Y453	G89-V93 WeakPolarHBondContact O-CG2 3.34Å; G89-V93 PolarHBondContact O-N 2.72Å; G89-V93 VanDerWaalsContact O-N 3.09Å; N90-V93 PolarHBondContact O-N 3.43Å; V93-W95 VanDerWaalsContact C-N 3.34Å; V93-W95 PolarHBondContact O-N 2.92Å; V93-V96 PolarHBondContact O-N 2.9Å; V93-L97 HydrophobicContact CG1-CD1 3.7Å; V93-L97 HydrophobicContact CG1-CG 4.17Å; V93-L97 WeakPolarHBondContact O-CB 3.27Å; V93-L97 VanDerWaalsContact O-CG 3.26Å; V93-L97 WeakPolarHBondContact O-CG 3.42Å; V93-L97 PolarHBondContact O-N 3.23Å; V93-P450 HydrophobicContact CG2-CB 3.97Å; V93-Y453 HydrophobicContact CG1-CD2 4Å
94	L	89.7	Confident	82.2	Confident	28 Å²	28	82.1 Å²	82.1	15%	0.147	39%	0.386	C	S	.	.	H	α-helix	trans	-58.4	-44.2	176	-179.1	60.2	0	0	0	111.6	N90 L97 L98 V112 C115 V116 L119	N90-L94 WeakPolarHBondContact O-CB 3.32Å; N90-L94 PolarHBondContact O-N 3.05Å; L94-L97 PolarHBondContact O-N 3Å; L94-L98 HydrophobicContact CD1-CD1 3.95Å; L94-L98 HydrophobicContact CD1-CG 4.02Å; L94-L98 HydrophobicContact CG-CD1 3.9Å; L94-L98 HydrophobicContact CG-CG 4.38Å; L94-L98 WeakPolarHBondContact O-CB 3.07Å; L94-L98 VanDerWaalsContact O-CG 3.25Å; L94-L98 WeakPolarHBondContact O-CG 3.5Å; L94-L98 PolarHBondContact O-N 3Å; L94-V112 HydrophobicContact CD1-CB 4.42Å; L94-V112 HydrophobicContact CD1-CG1 3.86Å; L94-V112 HydrophobicContact CD1-CG2 4.46Å; L94-C115 HydrophobicContact CB-CB 4.22Å; L94-V116 HydrophobicContact CD1-CG2 4.45Å; L94-V116 HydrophobicContact CD2-CG2 4.26Å; L94-L119 HydrophobicContact CD2-CD1 3.85Å
95	W	88	Confident	80.8	Confident	125 Å²	125	83.9 Å²	83.9	47%	0.473	40%	0.401	S	S	.	.	H	α-helix	trans	-62	-45.3	175.6	176.5	87.5	0	0	0	112.7	S91 F92 V93 L97 L98 R99 L467	S91-W95 WeakPolarHBondContact O-CB 3.45Å; S91-W95 PolarHBondContact O-N 2.73Å; F92-W95 PolarHBondContact O-N 3.1Å; V93-W95 VanDerWaalsContact C-N 3.34Å; V93-W95 PolarHBondContact O-N 2.92Å; W95-L97 PolarHBondContact O-N 3.29Å; W95-L98 PolarHBondContact O-N 3Å; W95-R99 VanDerWaalsContact O-CB 3.26Å; W95-R99 WeakPolarHBondContact O-CB 3.28Å; W95-R99 PolarHBondContact O-N 3.4Å; W95-L467 HydrophobicContact CZ3-CD1 4.2Å
96	V	84.3	Confident	79.8	Confident	11 Å²	11	81.2 Å²	81.2	7%	0.067	39%	0.389	C	S	.	.	H	α-helix	trans	-60.5	-45	175.3	173	0	0	0	0	111	F92 V93 R99 R100 E463 L467	F92-V96 HydrophobicContact CD1-CG2 4.44Å; F92-V96 HydrophobicContact CE1-CG2 3.98Å; F92-V96 HydrophobicContact CE2-CG2 4.26Å; F92-V96 HydrophobicContact CZ-CG2 3.89Å; F92-V96 WeakPolarHBondContact O-CG2 3.28Å; F92-V96 PolarHBondContact O-N 2.91Å; V93-V96 PolarHBondContact O-N 2.9Å; V96-R99 PolarHBondContact O-N 3.06Å; V96-R100 PolarHBondContact O-N 3.19Å; V96-E463 HydrophobicContact CG1-CB 4.34Å; V96-E463 HydrophobicContact CG1-CG 4Å; V96-L467 HydrophobicContact CG2-CD1 4.14Å
97	L	83	Confident	79	Confident	11 Å²	11	82.1 Å²	82.1	6%	0.058	39%	0.393	C	S	.	.	H	α-helix	trans	-64.8	-47.6	179.7	-70.4	171.1	0	0	0	111.8	V93 L94 W95 R99 R100 H108 M111 V112 V460	V93-L97 HydrophobicContact CG1-CD1 3.7Å; V93-L97 HydrophobicContact CG1-CG 4.17Å; V93-L97 WeakPolarHBondContact O-CB 3.27Å; V93-L97 VanDerWaalsContact O-CG 3.26Å; V93-L97 WeakPolarHBondContact O-CG 3.42Å; V93-L97 PolarHBondContact O-N 3.23Å; L94-L97 PolarHBondContact O-N 3Å; W95-L97 PolarHBondContact O-N 3.29Å; L97-R99 VanDerWaalsContact C-N 3.3Å; L97-R99 PolarHBondContact O-N 3.02Å; L97-R100 PolarHBondContact O-N 3.26Å; L97-H108 PolarHBondContact O-CE1 2.71Å; L97-H108 PolarHBondContact O-NE2 3.16Å; L97-M111 HydrophobicContact CD1-CB 3.63Å; L97-M111 HydrophobicContact CD2-SD 4.27Å; L97-V112 HydrophobicContact CB-CG2 3.84Å; L97-V112 HydrophobicContact CD1-CG2 4.03Å; L97-V460 HydrophobicContact CD2-CG2 4.26Å
98	L	84.8	Confident	78.4	Confident	114 Å²	114	82.8 Å²	82.8	60%	0.597	39%	0.394	S	S	*	.	H	α-helix	trans	-62.9	-36.1	178.7	-72.6	174.1	0	0	0	112.1	L94 W95 R100	L94-L98 HydrophobicContact CD1-CD1 3.95Å; L94-L98 HydrophobicContact CD1-CG 4.02Å; L94-L98 HydrophobicContact CG-CD1 3.9Å; L94-L98 HydrophobicContact CG-CG 4.38Å; L94-L98 WeakPolarHBondContact O-CB 3.07Å; L94-L98 VanDerWaalsContact O-CG 3.25Å; L94-L98 WeakPolarHBondContact O-CG 3.5Å; L94-L98 PolarHBondContact O-N 3Å; W95-L98 PolarHBondContact O-N 3Å; L98-R100 VanDerWaalsContact C-N 3.28Å; L98-R100 PolarHBondContact O-N 3.36Å
99	R	81.9	Confident	78	Confident	169 Å²	169	79.1 Å²	79.1	64%	0.638	38%	0.375	S	S	*	.	H	α-helix	trans	-72	-16.3	-179.7	-164.5	171.9	-173.7	-171.7	1	113.8	W95 V96 L97	W95-R99 VanDerWaalsContact O-CB 3.26Å; W95-R99 WeakPolarHBondContact O-CB 3.28Å; W95-R99 PolarHBondContact O-N 3.4Å; V96-R99 PolarHBondContact O-N 3.06Å; L97-R99 VanDerWaalsContact C-N 3.3Å; L97-R99 PolarHBondContact O-N 3.02Å
100	R	70.4	Confident	77.8	Confident	129 Å²	129	78.3 Å²	78.3	49%	0.487	37%	0.366	S	S	.	.			trans	-120.3	82.4	-177.1	-68.3	-61.9	-157.9	146.2	10.9	112.5	V96 L97 L98 K102 E463	V96-R100 PolarHBondContact O-N 3.19Å; L97-R100 PolarHBondContact O-N 3.26Å; L98-R100 VanDerWaalsContact C-N 3.28Å; L98-R100 PolarHBondContact O-N 3.36Å; R100-K102 PolarHBondContact O-N 3.5Å; R100-E463 IonicContact CZ-OE1 3.87Å; R100-E463 IonicContact CZ-OE2 3.5Å; R100-E463 IonicContact NE-OE1 3.69Å; R100-E463 PolarHBondContact NE-OE1 2.84Å; R100-E463 IonicContact NE-OE2 2.71Å; R100-E463 IonicContact NH2-OE1 3.93Å; R100-E463 PolarHBondContact NH2-OE1 2.76Å; R100-E463 IonicContact NH2-OE2 2.72Å; R100-E463 PolarHBondContact NH2-OE2 2.81Å
101	R	64.3	Low	77.5	Confident	243 Å²	243	78.5 Å²	78.5	92%	0.917	37%	0.366	S	S	*	.			trans	-65.6	121.9	167.6	-92.6	-175.1	169.2	-176	-2.2	110.9
102	K	61.2	Low	77.4	Confident	192 Å²	192	77 Å²	77	84%	0.835	36%	0.355	S	S	*	.			trans	66.9	145.2	-171.5	-62.3	-176.4	177.4	-179.1	0	112.6	R100	R100-K102 PolarHBondContact O-N 3.5Å
103	H	52.6	Low	77.5	Confident	148 Å²	148	74.3 Å²	74.3	69%	0.685	34%	0.344	S	S	*	.	S	Bend	cis	-112.3	167.5	17.7	-149.2	-96.7	0	0	0	113.4
104	N	54.7	Low	77.6	Confident	97 Å²	97	74.5 Å²	74.5	52%	0.519	35%	0.345	S	S	.	.			trans	72	68.8	-177.5	-51.8	-13	0	0	0	115.4	H108	N104-H108 PolarHBondContact O-N 3.32Å
105	A	64.5	Low	77.8	Confident	80 Å²	80	73.1 Å²	73.1	66%	0.661	34%	0.338	S	S	*	.	H	α-helix	trans	-50.5	-52.3	-171.6	0	0	0	0	0	117.6	L109	A105-L109 PolarHBondContact O-N 2.99Å
106	P	68.4	Low	78.1	Confident	35 Å²	35	69.8 Å²	69.8	23%	0.227	33%	0.331	C	S	.	.	H	α-helix	trans	-70.1	-42.8	-173.8	25.7	-33.5	0	0	0	112.2	H108 L109 F110 W189	P106-H108 VanDerWaalsContact C-N 3.31Å; P106-H108 PolarHBondContact O-N 3.47Å; P106-L109 PolarHBondContact O-N 2.94Å; P106-F110 WeakPolarHBondContact O-CD2 3.45Å; P106-F110 PolarHBondContact O-N 2.96Å; P106-W189 HydrophobicContact CB-CE3 4.21Å
107	M	74.1	Confident	78.5	Confident	20 Å²	20	69.2 Å²	69.2	10%	0.099	33%	0.328	C	S	.	.	H	α-helix	trans	-65.1	-36.6	-177	-157	-170.6	177.3	0	0	112	F110 M111 M166 R170 M400	M107-F110 PolarHBondContact O-N 3.37Å; M107-M111 HydrophobicContact CE-CE 3.61Å; M107-M111 HydrophobicContact CG-CE 3.79Å; M107-M111 WeakPolarHBondContact O-CG 3.3Å; M107-M111 PolarHBondContact O-N 2.87Å; M107-M111 HydrophobicContact SD-CE 3.84Å; M107-M166 HydrophobicContact CE-CE 4.08Å; M107-R170 PolarHBondContact SD-NH1 3.22Å; M107-M400 HydrophobicContact CE-CE 4.1Å; M107-M400 HydrophobicContact CE-SD 3.41Å; M107-M400 WeakPolarHBondContact CE-SD 3.45Å
108	H	79.4	Confident	79	Confident	48 Å²	48	68.7 Å²	68.7	22%	0.222	33%	0.325	C	S	.	.	H	α-helix	trans	-63.5	-43.7	175.4	-180	-82.2	0	0	0	111.8	L97 N104 P106 F110 M111 V112	L97-H108 PolarHBondContact O-CE1 2.71Å; L97-H108 PolarHBondContact O-NE2 3.16Å; N104-H108 PolarHBondContact O-N 3.32Å; P106-H108 VanDerWaalsContact C-N 3.31Å; P106-H108 PolarHBondContact O-N 3.47Å; H108-F110 VanDerWaalsContact C-N 3.35Å; H108-F110 PolarHBondContact O-N 3.3Å; H108-M111 PolarHBondContact O-N 3.39Å; H108-V112 WeakPolarHBondContact O-CG2 3.43Å; H108-V112 PolarHBondContact O-N 3.47Å
109	L	85.1	Confident	79.4	Confident	50 Å²	50	64.5 Å²	64.5	26%	0.262	30%	0.303	S	S	.	.	H	α-helix	trans	-60.6	-41.4	177.4	-176.6	67	0	0	0	112.4	A105 P106 N113 N190 V193	A105-L109 PolarHBondContact O-N 2.99Å; P106-L109 PolarHBondContact O-N 2.94Å; L109-N113 WeakPolarHBondContact CD1-ND2 3.37Å; L109-N113 PolarHBondContact O-N 2.87Å; L109-N113 VanDerWaalsContact O-N 3.1Å; L109-N113 PolarHBondContact O-ND2 3.35Å; L109-N190 WeakPolarHBondContact CD2-OD1 3.41Å; L109-V193 HydrophobicContact CD2-CG2 4.1Å; L109-V193 HydrophobicContact CG-CG2 4.28Å
110	F	86.3	Confident	80	Confident	3 Å²	3	57.8 Å²	57.8	1%	0.013	28%	0.281	C	S	.	.	H	α-helix	trans	-63.6	-42.9	175.5	-68.9	-67.2	0	0	0	112.2	P106 M107 H108 N113 L114 M162 A165 M166 D169 P192 V193	P106-F110 WeakPolarHBondContact O-CD2 3.45Å; P106-F110 PolarHBondContact O-N 2.96Å; M107-F110 PolarHBondContact O-N 3.37Å; H108-F110 VanDerWaalsContact C-N 3.35Å; H108-F110 PolarHBondContact O-N 3.3Å; F110-N113 PolarHBondContact O-N 3.19Å; F110-L114 PolarHBondContact O-N 3.14Å; F110-M162 HydrophobicContact CB-CE 4.22Å; F110-M162 HydrophobicContact CD1-CE 3.68Å; F110-M162 HydrophobicContact CG-CE 4.44Å; F110-M162 WeakPolarHBondContact O-CE 3.45Å; F110-A165 HydrophobicContact CD1-CB 4.39Å; F110-A165 HydrophobicContact CE1-CB 3.8Å; F110-M166 HydrophobicContact CB-CB 4.38Å; F110-M166 HydrophobicContact CD1-CB 4.42Å; F110-M166 HydrophobicContact CG-CB 4.29Å; F110-D169 HydrophobicContact CE2-CB 3.63Å; F110-D169 HydrophobicContact CZ-CB 3.83Å; F110-P192 HydrophobicContact CE1-CB 4.26Å; F110-P192 HydrophobicContact CE1-CG 4.21Å; F110-P192 HydrophobicContact CZ-CB 4.17Å; F110-P192 HydrophobicContact CZ-CG 3.77Å; F110-V193 HydrophobicContact CD1-CG2 3.77Å; F110-V193 HydrophobicContact CE1-CG2 3.57Å; F110-V193 HydrophobicContact CZ-CG2 4.37Å
111	M	85.7	Confident	80.9	Confident	4 Å²	4	51.9 Å²	51.9	2%	0.02	26%	0.259	C	S	.	.	H	α-helix	trans	-62.5	-45.3	176.9	-62.3	-178.7	-161.7	0	0	112.2	L97 M107 H108 N113 L114 C115 M400 Y453	L97-M111 HydrophobicContact CD1-CB 3.63Å; L97-M111 HydrophobicContact CD2-SD 4.27Å; M107-M111 HydrophobicContact CE-CE 3.61Å; M107-M111 HydrophobicContact CG-CE 3.79Å; M107-M111 WeakPolarHBondContact O-CG 3.3Å; M107-M111 PolarHBondContact O-N 2.87Å; M107-M111 HydrophobicContact SD-CE 3.84Å; H108-M111 PolarHBondContact O-N 3.39Å; M111-N113 VanDerWaalsContact C-N 3.33Å; M111-N113 PolarHBondContact O-N 2.91Å; M111-L114 PolarHBondContact O-N 3.31Å; M111-C115 PolarHBondContact O-N 2.84Å; M111-M400 HydrophobicContact CE-CE 4.46Å; M111-Y453 HydrophobicContact CB-CE1 4.31Å; M111-Y453 HydrophobicContact CB-CE2 4.29Å; M111-Y453 HydrophobicContact CE-CD1 4.38Å; M111-Y453 HydrophobicContact CG-CD1 3.98Å; M111-Y453 HydrophobicContact CG-CE1 3.59Å; M111-Y453 HydrophobicContact CG-CE2 4.41Å; M111-Y453 HydrophobicContact SD-CD1 3.95Å; M111-Y453 HydrophobicContact SD-CE1 4.19Å; M111-Y453 HydrophobicContact SD-CG 4.36Å
112	V	89.3	Confident	82.2	Confident	23 Å²	23	40.3 Å²	40.3	14%	0.139	22%	0.215	C	C	.	.	H	α-helix	trans	-58.9	-45.2	177.9	167.6	0	0	0	0	111	L94 L97 H108 V116	L94-V112 HydrophobicContact CD1-CB 4.42Å; L94-V112 HydrophobicContact CD1-CG1 3.86Å; L94-V112 HydrophobicContact CD1-CG2 4.46Å; L97-V112 HydrophobicContact CB-CG2 3.84Å; L97-V112 HydrophobicContact CD1-CG2 4.03Å; H108-V112 WeakPolarHBondContact O-CG2 3.43Å; H108-V112 PolarHBondContact O-N 3.47Å; V112-V116 WeakPolarHBondContact O-CG2 3.44Å; V112-V116 PolarHBondContact O-N 3.23Å; V112-V116 VanDerWaalsContact O-N 3.1Å
113	N	92.2	Very high	83.6	Confident	28 Å²	28	35.3 Å²	35.3	15%	0.15	20%	0.197	C	C	.	.	H	α-helix	trans	-71.3	-33.7	-179.9	-81	-94.6	0	0	0	112.8	L109 F110 M111 V116 A117 M162 V193 W197	L109-N113 WeakPolarHBondContact CD1-ND2 3.37Å; L109-N113 PolarHBondContact O-N 2.87Å; L109-N113 VanDerWaalsContact O-N 3.1Å; L109-N113 PolarHBondContact O-ND2 3.35Å; F110-N113 PolarHBondContact O-N 3.19Å; M111-N113 VanDerWaalsContact C-N 3.33Å; M111-N113 PolarHBondContact O-N 2.91Å; N113-V116 PolarHBondContact O-N 3.41Å; N113-A117 PolarHBondContact O-N 2.89Å; N113-M162 HydrophobicContact CB-CE 3.32Å; N113-M162 HydrophobicContact CB-SD 3.89Å; N113-V193 HydrophobicContact CB-CG1 4.31Å; N113-V193 WeakPolarHBondContact OD1-CG1 3.33Å; N113-W197 PolarHBondContact OD1-NE1 3.28Å
114	L	90	Very high	85.3	Confident	6 Å²	6	31.3 Å²	31.3	3%	0.031	18%	0.178	C	C	.	.	H	α-helix	trans	-68.4	-43.9	174.7	-164.8	70.6	0	0	0	111.4	F110 M111 V116 A117 D118 S159 M162 I163 N449 Y453	F110-L114 PolarHBondContact O-N 3.14Å; M111-L114 PolarHBondContact O-N 3.31Å; L114-V116 PolarHBondContact O-N 3.46Å; L114-A117 PolarHBondContact O-N 3.35Å; L114-A117 VanDerWaalsContact O-N 3.08Å; L114-D118 PolarHBondContact O-N 3.5Å; L114-S159 WeakPolarHBondContact CD1-O 3.19Å; L114-M162 HydrophobicContact CD1-CB 3.62Å; L114-I163 HydrophobicContact CD1-CG1 4.17Å; L114-I163 HydrophobicContact CD2-CG1 4.24Å; L114-N449 HydrophobicContact CD2-CB 4.34Å; L114-N449 WeakPolarHBondContact CD2-ND2 3.48Å; L114-Y453 WeakPolarHBondContact CB-OH 3.31Å; L114-Y453 WeakPolarHBondContact CD2-OH 3.31Å
115	C	92.9	Very high	86.7	Confident	0 Å²	0	26.9 Å²	26.9	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-60.5	-32.6	173.4	-70.3	0	0	0	0	112.5	N90 L94 M111 L119	N90-C115 HydrophobicContact CB-CB 4.19Å; N90-C115 PolarHBondContact OD1-SG 2.96Å; L94-C115 HydrophobicContact CB-CB 4.22Å; M111-C115 PolarHBondContact O-N 2.84Å; C115-L119 WeakPolarHBondContact O-CB 3.41Å; C115-L119 WeakPolarHBondContact O-CD1 3.2Å; C115-L119 WeakPolarHBondContact O-CG 3.39Å; C115-L119 PolarHBondContact O-N 3.03Å
116	V	94.1	Very high	87.6	Confident	54 Å²	54	23.1 Å²	23.1	33%	0.327	12%	0.123	S	C	.	.	H	α-helix	trans	-68.3	-44.2	171.6	169.3	0	0	0	0	111.5	L94 V112 N113 L114 L119 V120 W197	L94-V116 HydrophobicContact CD1-CG2 4.45Å; L94-V116 HydrophobicContact CD2-CG2 4.26Å; V112-V116 WeakPolarHBondContact O-CG2 3.44Å; V112-V116 PolarHBondContact O-N 3.23Å; V112-V116 VanDerWaalsContact O-N 3.1Å; N113-V116 PolarHBondContact O-N 3.41Å; L114-V116 PolarHBondContact O-N 3.46Å; V116-L119 PolarHBondContact O-N 2.77Å; V116-V120 WeakPolarHBondContact O-CG2 3.24Å; V116-V120 PolarHBondContact O-N 2.88Å; V116-W197 HydrophobicContact CG1-CH2 4.24Å; V116-W197 HydrophobicContact CG1-CZ2 4.08Å
117	A	93.9	Very high	88.5	Confident	0 Å²	0	24.4 Å²	24.4	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-62.3	-42.5	176.3	0	0	0	0	0	112.4	N113 L114 L119 V120 V121 A158	N113-A117 PolarHBondContact O-N 2.89Å; L114-A117 PolarHBondContact O-N 3.35Å; L114-A117 VanDerWaalsContact O-N 3.08Å; A117-L119 VanDerWaalsContact C-N 3.31Å; A117-L119 PolarHBondContact O-N 3.22Å; A117-V120 WeakPolarHBondContact O-CB 3.35Å; A117-V120 PolarHBondContact O-N 3.32Å; A117-V120 VanDerWaalsContact O-N 3.14Å; A117-V121 PolarHBondContact O-N 3.45Å; A117-A158 HydrophobicContact CB-CB 3.79Å
118	D	93.3	Very high	88.9	Confident	0 Å²	0	24.1 Å²	24.1	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-68.2	-28.7	176.8	-70	-26.1	0	0	0	112.6	L114 A122 S159 S446 N449	L114-D118 PolarHBondContact O-N 3.5Å; D118-A122 WeakPolarHBondContact O-CB 3.5Å; D118-A122 PolarHBondContact O-N 3.29Å; D118-S159 PolarHBondContact OD1-OG 3.41Å; D118-S446 WeakPolarHBondContact OD1-CB 3.48Å; D118-S446 PolarHBondContact OD1-OG 3.37Å; D118-N449 PolarHBondContact OD2-ND2 3.44Å
119	L	94.1	Very high	88.9	Confident	26 Å²	26	22.5 Å²	22.5	14%	0.136	12%	0.12	C	C	.	.	H	α-helix	trans	-73.4	-33.6	169.5	-73.5	169.5	0	0	0	112.4	N90 L94 C115 V116 A117 A122 L123	N90-L119 HydrophobicContact CB-CD2 4.25Å; N90-L119 HydrophobicContact CB-CG 4.06Å; L94-L119 HydrophobicContact CD2-CD1 3.85Å; C115-L119 WeakPolarHBondContact O-CB 3.41Å; C115-L119 WeakPolarHBondContact O-CD1 3.2Å; C115-L119 WeakPolarHBondContact O-CG 3.39Å; C115-L119 PolarHBondContact O-N 3.03Å; V116-L119 PolarHBondContact O-N 2.77Å; A117-L119 VanDerWaalsContact C-N 3.31Å; A117-L119 PolarHBondContact O-N 3.22Å; L119-A122 PolarHBondContact O-N 2.99Å; L119-L123 WeakPolarHBondContact O-CB 3.31Å; L119-L123 VanDerWaalsContact O-CG 3.28Å; L119-L123 WeakPolarHBondContact O-CG 3.39Å; L119-L123 PolarHBondContact O-N 3.45Å
120	V	92.5	Very high	88.7	Confident	27 Å²	27	21.1 Å²	21.1	16%	0.164	11%	0.113	C	C	.	.	H	α-helix	trans	-64	-43.1	169.6	171.8	0	0	0	0	110.4	V116 A117 L123 F124	V116-V120 WeakPolarHBondContact O-CG2 3.24Å; V116-V120 PolarHBondContact O-N 2.88Å; A117-V120 WeakPolarHBondContact O-CB 3.35Å; A117-V120 PolarHBondContact O-N 3.32Å; A117-V120 VanDerWaalsContact O-N 3.14Å; V120-L123 PolarHBondContact O-N 2.87Å; V120-F124 HydrophobicContact CG1-CD2 3.96Å; V120-F124 WeakPolarHBondContact O-CB 3.35Å; V120-F124 WeakPolarHBondContact O-CD2 3.26Å; V120-F124 PolarHBondContact O-N 3.2Å
121	V	90.1	Very high	88.5	Confident	5 Å²	5	25 Å²	25	3%	0.03	13%	0.133	C	C	.	.	H	α-helix	trans	-57.7	-49	171.2	167.3	0	0	0	0	110.9	A117 L123 Q125 V126	A117-V121 PolarHBondContact O-N 3.45Å; V121-L123 VanDerWaalsContact C-N 3.35Å; V121-L123 PolarHBondContact O-N 2.95Å; V121-Q125 HydrophobicContact CG1-CB 4.29Å; V121-Q125 WeakPolarHBondContact O-CA 3.42Å; V121-Q125 WeakPolarHBondContact O-CB 3.37Å; V121-Q125 PolarHBondContact O-N 3.39Å; V121-V126 HydrophobicContact CG1-CG2 4.34Å; V121-V126 PolarHBondContact O-N 3.15Å
122	A	90.8	Very high	88.1	Confident	0 Å²	0	26.8 Å²	26.8	0%	0	14%	0.139	C	C	.	.	I	π-helix	trans	-59.1	-43.4	178.7	0	0	0	0	0	113.1	L83 T86 T87 D118 L119 L127	L83-A122 HydrophobicContact CD1-CB 4.19Å; L83-A122 VanDerWaalsContact CD1-O 3.29Å; L83-A122 WeakPolarHBondContact CD1-O 3.43Å; T86-A122 HydrophobicContact CG2-CB 3.9Å; T87-A122 HydrophobicContact CG2-CB 3.68Å; D118-A122 WeakPolarHBondContact O-CB 3.5Å; D118-A122 PolarHBondContact O-N 3.29Å; L119-A122 PolarHBondContact O-N 2.99Å; A122-L127 WeakPolarHBondContact O-CB 3.07Å; A122-L127 PolarHBondContact O-N 3.5Å
123	L	91.2	Very high	87.3	Confident	88 Å²	88	25.8 Å²	25.8	46%	0.461	13%	0.133	S	C	.	.	I	π-helix	trans	-83	-28.3	-174.4	-68.4	172	0	0	0	114.8	L119 V120 V121 L127 P128	L119-L123 WeakPolarHBondContact O-CB 3.31Å; L119-L123 VanDerWaalsContact O-CG 3.28Å; L119-L123 WeakPolarHBondContact O-CG 3.39Å; L119-L123 PolarHBondContact O-N 3.45Å; V120-L123 PolarHBondContact O-N 2.87Å; V121-L123 VanDerWaalsContact C-N 3.35Å; V121-L123 PolarHBondContact O-N 2.95Å; L123-L127 HydrophobicContact CD2-CD2 4.33Å; L123-P128 WeakPolarHBondContact O-CD 3.36Å
124	F	87.9	Confident	86.6	Confident	64 Å²	64	29.3 Å²	29.3	28%	0.281	15%	0.151	S	C	.	.	I	π-helix	trans	-117.7	-14.3	-174.3	-63.5	-78.9	0	0	0	114.7	V120 P128 L151	V120-F124 HydrophobicContact CG1-CD2 3.96Å; V120-F124 WeakPolarHBondContact O-CB 3.35Å; V120-F124 WeakPolarHBondContact O-CD2 3.26Å; V120-F124 PolarHBondContact O-N 3.2Å; F124-P128 WeakPolarHBondContact O-CG 3.49Å; F124-L151 HydrophobicContact CB-CB 3.8Å; F124-L151 HydrophobicContact CD1-CB 3.85Å; F124-L151 HydrophobicContact CD1-CD1 3.73Å; F124-L151 HydrophobicContact CD1-CG 4.45Å; F124-L151 HydrophobicContact CD2-CB 4.05Å; F124-L151 HydrophobicContact CD2-CD1 4.3Å; F124-L151 HydrophobicContact CE1-CB 4.46Å; F124-L151 HydrophobicContact CE1-CD1 3.49Å; F124-L151 VanDerWaalsContact CE1-CD1 3.49Å; F124-L151 HydrophobicContact CE2-CD1 4.08Å; F124-L151 HydrophobicContact CG-CB 3.61Å; F124-L151 HydrophobicContact CG-CD1 4.13Å; F124-L151 HydrophobicContact CZ-CD1 3.68Å
125	Q	84.4	Confident	85.9	Confident	3 Å²	3	31.8 Å²	31.8	1%	0.014	17%	0.166	C	C	.	.	I	π-helix	trans	-104.5	-60.2	169.5	-176.2	179.7	-14.7	0	0	111	L45 V121 Q129 Q152	L45-Q125 HydrophobicContact CD2-CG 4.03Å; V121-Q125 HydrophobicContact CG1-CB 4.29Å; V121-Q125 WeakPolarHBondContact O-CA 3.42Å; V121-Q125 WeakPolarHBondContact O-CB 3.37Å; V121-Q125 PolarHBondContact O-N 3.39Å; Q125-Q129 VanDerWaalsContact O-CB 3.23Å; Q125-Q129 WeakPolarHBondContact O-CB 3.48Å; Q125-Q129 PolarHBondContact O-N 3.47Å; Q125-Q152 HydrophobicContact CB-CB 4.5Å; Q125-Q152 HydrophobicContact CB-CG 3.89Å; Q125-Q152 HydrophobicContact CG-CG 3.95Å
126	V	84.4	Confident	84.7	Confident	1 Å²	1	36.9 Å²	36.9	1%	0.006	19%	0.19	C	C	.	.	I	π-helix	trans	-76.9	-44.2	-168.6	-170.2	0	0	0	0	112.4	L79 V82 L83 V121 L130	L79-V126 HydrophobicContact CD2-CG1 4.31Å; V82-V126 HydrophobicContact CG1-CG1 4.18Å; L83-V126 HydrophobicContact CB-CG1 3.87Å; L83-V126 HydrophobicContact CD1-CB 4.19Å; L83-V126 HydrophobicContact CD1-CG1 4.27Å; V121-V126 HydrophobicContact CG1-CG2 4.34Å; V121-V126 PolarHBondContact O-N 3.15Å; V126-L130 WeakPolarHBondContact O-CB 3.4Å; V126-L130 PolarHBondContact O-N 3.09Å
127	L	86.9	Confident	83.4	Confident	62 Å²	62	39.7 Å²	39.7	33%	0.325	20%	0.195	S	C	.	.	H	α-helix	trans	-63.8	-47	178.2	171.2	65.2	0	0	0	112.8	L83 A122 L123 L130 I131	L83-L127 HydrophobicContact CD1-CB 4.06Å; L83-L127 HydrophobicContact CD2-CB 4.22Å; L83-L127 HydrophobicContact CD2-CD1 4.02Å; A122-L127 WeakPolarHBondContact O-CB 3.07Å; A122-L127 PolarHBondContact O-N 3.5Å; L123-L127 HydrophobicContact CD2-CD2 4.33Å; L127-L130 PolarHBondContact O-N 3.23Å; L127-I131 HydrophobicContact CD1-CD1 3.93Å; L127-I131 HydrophobicContact CD1-CG1 4.25Å; L127-I131 HydrophobicContact CG-CD1 4.04Å; L127-I131 WeakPolarHBondContact O-CG1 3.2Å; L127-I131 PolarHBondContact O-N 3.48Å
128	P	82.9	Confident	82.3	Confident	15 Å²	15	40.7 Å²	40.7	10%	0.097	20%	0.199	C	C	.	.	H	α-helix	trans	-66.2	-39.6	178.3	-24.5	38.2	0	0	0	112.1	L123 F124 L130 I131 W132 V148	L123-P128 WeakPolarHBondContact O-CD 3.36Å; F124-P128 WeakPolarHBondContact O-CG 3.49Å; P128-L130 PolarHBondContact O-N 3.31Å; P128-I131 WeakPolarHBondContact O-CB 3.35Å; P128-I131 PolarHBondContact O-N 2.83Å; P128-I131 VanDerWaalsContact O-N 3.16Å; P128-W132 HydrophobicContact CB-CE3 4.11Å; P128-W132 HydrophobicContact CB-CZ3 4.01Å; P128-W132 PolarHBondContact O-N 3.4Å; P128-V148 HydrophobicContact CB-CG1 3.81Å; P128-V148 HydrophobicContact CG-CG1 3.89Å; P128-V148 HydrophobicContact CG-CG2 4.49Å
129	Q	78	Confident	81.3	Confident	13 Å²	13	49 Å²	49	6%	0.061	24%	0.238	C	C	.	.	H	α-helix	trans	-53.3	-54.1	172.5	176.7	64.2	32.1	0	0	111.3	G43 S44 L45 L79 Q125 I131 W132 D133	G43-Q129 PolarHBondContact O-NE2 2.71Å; S44-Q129 PolarHBondContact O-OE1 3.34Å; L45-Q129 VanDerWaalsContact CA-OE1 3.32Å; L45-Q129 HydrophobicContact CG-CG 4.42Å; L79-Q129 HydrophobicContact CD1-CG 3.89Å; L79-Q129 HydrophobicContact CD2-CG 4.08Å; Q125-Q129 VanDerWaalsContact O-CB 3.23Å; Q125-Q129 WeakPolarHBondContact O-CB 3.48Å; Q125-Q129 PolarHBondContact O-N 3.47Å; Q129-I131 VanDerWaalsContact C-N 3.25Å; Q129-I131 PolarHBondContact O-N 3.42Å; Q129-W132 WeakPolarHBondContact O-CB 3.35Å; Q129-W132 PolarHBondContact O-N 3.09Å; Q129-D133 VanDerWaalsContact NE2-CG 3.33Å; Q129-D133 PolarHBondContact NE2-OD1 3.43Å; Q129-D133 PolarHBondContact NE2-OD2 3.48Å; Q129-D133 PolarHBondContact O-N 2.92Å
130	L	81.5	Confident	80.5	Confident	22 Å²	22	48 Å²	48	12%	0.115	23%	0.234	C	C	.	.	H	α-helix	trans	-58.1	-36.1	177.9	179	63.9	0	0	0	112.6	I76 L79 L83 V126 L127 P128 I134	I76-L130 HydrophobicContact CB-CD1 4.4Å; I76-L130 HydrophobicContact CG2-CD1 3.9Å; I76-L130 WeakPolarHBondContact O-CD1 3.33Å; L79-L130 HydrophobicContact CB-CB 4.47Å; L79-L130 HydrophobicContact CB-CD1 3.97Å; L83-L130 HydrophobicContact CD2-CD2 3.74Å; V126-L130 WeakPolarHBondContact O-CB 3.4Å; V126-L130 PolarHBondContact O-N 3.09Å; L127-L130 PolarHBondContact O-N 3.23Å; P128-L130 PolarHBondContact O-N 3.31Å; L130-I134 HydrophobicContact CD1-CD1 3.92Å; L130-I134 HydrophobicContact CG-CD1 4.03Å; L130-I134 VanDerWaalsContact O-CD1 3.3Å; L130-I134 WeakPolarHBondContact O-CD1 3.3Å; L130-I134 WeakPolarHBondContact O-CG1 3.25Å; L130-I134 PolarHBondContact O-N 2.81Å
131	I	82.7	Confident	80.2	Confident	83 Å²	83	50.6 Å²	50.6	43%	0.426	25%	0.251	S	S	.	.	H	α-helix	trans	-65.3	-49.5	173.4	-68.9	164.9	0	0	0	110.2	L127 P128 Q129 D133 I134 T135	L127-I131 HydrophobicContact CD1-CD1 3.93Å; L127-I131 HydrophobicContact CD1-CG1 4.25Å; L127-I131 HydrophobicContact CG-CD1 4.04Å; L127-I131 WeakPolarHBondContact O-CG1 3.2Å; L127-I131 PolarHBondContact O-N 3.48Å; P128-I131 WeakPolarHBondContact O-CB 3.35Å; P128-I131 PolarHBondContact O-N 2.83Å; P128-I131 VanDerWaalsContact O-N 3.16Å; Q129-I131 VanDerWaalsContact C-N 3.25Å; Q129-I131 PolarHBondContact O-N 3.42Å; I131-D133 VanDerWaalsContact C-N 3.31Å; I131-D133 PolarHBondContact O-N 2.9Å; I131-I134 PolarHBondContact O-N 3.3Å; I131-I134 VanDerWaalsContact O-N 3.15Å; I131-T135 HydrophobicContact CG2-CG2 4.02Å; I131-T135 PolarHBondContact O-N 3.4Å; I131-T135 PolarHBondContact O-OG1 3.47Å
132	W	76.4	Confident	80	Confident	43 Å²	43	52.9 Å²	52.9	16%	0.163	26%	0.264	C	S	.	.	H	α-helix	trans	-57.1	-41.1	179.8	-109.4	-74.5	0	0	0	112.9	P128 Q129 I134 E136 F138 V148 C223	P128-W132 HydrophobicContact CB-CE3 4.11Å; P128-W132 HydrophobicContact CB-CZ3 4.01Å; P128-W132 PolarHBondContact O-N 3.4Å; Q129-W132 WeakPolarHBondContact O-CB 3.35Å; Q129-W132 PolarHBondContact O-N 3.09Å; W132-I134 VanDerWaalsContact C-N 3.3Å; W132-I134 PolarHBondContact O-N 2.96Å; W132-E136 WeakPolarHBondContact O-CA 3.26Å; W132-E136 PolarHBondContact O-N 3Å; W132-F138 AromaticContact CE2-CD2 3.93Å; W132-F138 AromaticContact CH2-CD2 3.38Å; W132-F138 HydrophobicContact CH2-CD2 3.38Å; W132-F138 AromaticContact CH2-CE2 3.65Å; W132-F138 HydrophobicContact CH2-CE2 3.65Å; W132-F138 HydrophobicContact CH2-CG 4.17Å; W132-F138 HydrophobicContact CZ2-CB 3.66Å; W132-F138 AromaticContact CZ2-CD2 3.17Å; W132-F138 HydrophobicContact CZ2-CD2 3.17Å; W132-F138 AromaticContact CZ2-CE2 3.92Å; W132-F138 HydrophobicContact CZ2-CE2 3.92Å; W132-F138 AromaticContact CZ2-CG 3.55Å; W132-F138 HydrophobicContact CZ2-CG 3.55Å; W132-F138 HydrophobicContact CZ3-CD2 4.28Å; W132-V148 HydrophobicContact CZ3-CG1 4.28Å; W132-C223 HydrophobicContact CH2-CB 4.02Å; W132-C223 HydrophobicContact CZ2-CB 3.63Å
133	D	72.4	Confident	80	Confident	1 Å²	1	59.4 Å²	59.4	1%	0.005	30%	0.298	C	S	.	.	H	α-helix	trans	-73	-23.6	-178.8	-61	-34.2	0	0	0	113.2	G43 R67 I76 L79 Q129 I131	G43-D133 PolarHBondContact N-OD1 3.5Å; R67-D133 PolarHBondContact NH2-O 3.44Å; I76-D133 HydrophobicContact CG1-CB 4.04Å; L79-D133 WeakPolarHBondContact CD1-OD2 3.42Å; Q129-D133 VanDerWaalsContact NE2-CG 3.33Å; Q129-D133 PolarHBondContact NE2-OD1 3.43Å; Q129-D133 PolarHBondContact NE2-OD2 3.48Å; Q129-D133 PolarHBondContact O-N 2.92Å; I131-D133 VanDerWaalsContact C-N 3.31Å; I131-D133 PolarHBondContact O-N 2.9Å
134	I	77.9	Confident	79.8	Confident	102 Å²	102	59 Å²	59	52%	0.523	30%	0.296	S	S	.	.	H	α-helix	trans	-86.9	-42.8	175.6	-68.7	169.6	0	0	0	112	I76 L130 I131 W132	I76-I134 HydrophobicContact CD1-CG1 3.93Å; I76-I134 HydrophobicContact CG1-CG1 4.15Å; I76-I134 HydrophobicContact CG2-CD1 4.1Å; I76-I134 HydrophobicContact CG2-CG1 4Å; L130-I134 HydrophobicContact CD1-CD1 3.92Å; L130-I134 HydrophobicContact CG-CD1 4.03Å; L130-I134 VanDerWaalsContact O-CD1 3.3Å; L130-I134 WeakPolarHBondContact O-CD1 3.3Å; L130-I134 WeakPolarHBondContact O-CG1 3.25Å; L130-I134 PolarHBondContact O-N 2.81Å; I131-I134 PolarHBondContact O-N 3.3Å; I131-I134 VanDerWaalsContact O-N 3.15Å; W132-I134 VanDerWaalsContact C-N 3.3Å; W132-I134 PolarHBondContact O-N 2.96Å
135	T	75.2	Confident	79.6	Confident	58 Å²	58	56 Å²	56	36%	0.356	28%	0.282	S	S	.	.	H	α-helix	trans	-87.7	-16.1	-175.9	61.1	0	0	0	0	113.6	I131 R137	I131-T135 HydrophobicContact CG2-CG2 4.02Å; I131-T135 PolarHBondContact O-N 3.4Å; I131-T135 PolarHBondContact O-OG1 3.47Å; T135-R137 PolarHBondContact O-N 3.46Å; T135-R137 PolarHBondContact OG1-O 3.45Å
136	E	66.9	Low	79.8	Confident	107 Å²	107	59.3 Å²	59.3	50%	0.5	30%	0.295	S	S	.	.	S	Bend	trans	55.8	3.6	-174.4	-57.3	-174	153.9	0	0	114.8	R67 W132	R67-E136 IonicContact CZ-OE1 3.24Å; R67-E136 VanDerWaalsContact CZ-OE1 3.24Å; R67-E136 IonicContact NE-OE1 3.1Å; R67-E136 PolarHBondContact NE-OE1 3.32Å; R67-E136 VanDerWaalsContact NE-OE1 3.1Å; R67-E136 IonicContact NH2-OE1 2.68Å; R67-E136 PolarHBondContact NH2-OE1 2.97Å; W132-E136 WeakPolarHBondContact O-CA 3.26Å; W132-E136 PolarHBondContact O-N 3Å
137	R	67.9	Low	80	Confident	114 Å²	114	61.1 Å²	61.1	43%	0.43	31%	0.307	S	S	.	.	S	Bend	trans	-152.1	151.8	-173.7	-73.4	-176.2	174.2	75.4	-4.9	112.2	T135 E220	T135-R137 PolarHBondContact O-N 3.46Å; T135-R137 PolarHBondContact OG1-O 3.45Å; R137-E220 WeakPolarHBondContact CD-OE2 3.43Å; R137-E220 IonicContact CZ-OE1 3.34Å; R137-E220 IonicContact CZ-OE2 3.77Å; R137-E220 IonicContact NE-OE1 3.14Å; R137-E220 PolarHBondContact NE-OE1 3.4Å; R137-E220 VanDerWaalsContact NE-OE1 3.14Å; R137-E220 IonicContact NE-OE2 2.82Å; R137-E220 PolarHBondContact NE-OE2 3.12Å; R137-E220 IonicContact NH2-OE1 2.69Å; R137-E220 PolarHBondContact NH2-OE1 3.1Å; R137-E220 IonicContact NH2-OE2 3.86Å
138	F	71.4	Confident	80	Confident	20 Å²	20	58.7 Å²	58.7	9%	0.088	30%	0.295	C	S	.	.			trans	-94.6	108.8	174.7	-179.5	-115.4	0	0	0	112.7	W132 G140 L144 C145 C223	W132-F138 AromaticContact CE2-CD2 3.93Å; W132-F138 AromaticContact CH2-CD2 3.38Å; W132-F138 HydrophobicContact CH2-CD2 3.38Å; W132-F138 AromaticContact CH2-CE2 3.65Å; W132-F138 HydrophobicContact CH2-CE2 3.65Å; W132-F138 HydrophobicContact CH2-CG 4.17Å; W132-F138 HydrophobicContact CZ2-CB 3.66Å; W132-F138 AromaticContact CZ2-CD2 3.17Å; W132-F138 HydrophobicContact CZ2-CD2 3.17Å; W132-F138 AromaticContact CZ2-CE2 3.92Å; W132-F138 HydrophobicContact CZ2-CE2 3.92Å; W132-F138 AromaticContact CZ2-CG 3.55Å; W132-F138 HydrophobicContact CZ2-CG 3.55Å; W132-F138 HydrophobicContact CZ3-CD2 4.28Å; F138-G140 VanDerWaalsContact C-N 3.34Å; F138-G140 WeakPolarHBondContact CE1-O 3.13Å; F138-G140 VanDerWaalsContact CZ-CA 3.41Å; F138-G140 PolarHBondContact O-N 3.33Å; F138-L144 HydrophobicContact CE2-CD2 4.45Å; F138-L144 HydrophobicContact CZ-CB 4.35Å; F138-L144 HydrophobicContact CZ-CG 4.44Å; F138-C145 HydrophobicContact CE1-CB 3.75Å; F138-C145 HydrophobicContact CZ-CB 3.7Å; F138-C223 HydrophobicContact CD1-CB 4.25Å; F138-C223 HydrophobicContact CE1-CB 4.47Å; F138-C223 HydrophobicContact CG-CB 4.39Å
139	Q	70.6	Confident	80	Confident	175 Å²	175	58.8 Å²	58.8	82%	0.818	29%	0.294	S	S	*	.			trans	-91.5	16.6	179.9	-58.6	-170.3	6.3	0	0	114.2
140	G	77.9	Confident	80.6	Confident	6 Å²	6	60.5 Å²	60.5	6%	0.062	30%	0.3	C	S	.	.	S	Bend	trans	-98.1	164.1	-171.8	0	0	0	0	0	116.2	F138 R213	F138-G140 VanDerWaalsContact C-N 3.34Å; F138-G140 WeakPolarHBondContact CE1-O 3.13Å; F138-G140 VanDerWaalsContact CZ-CA 3.41Å; F138-G140 PolarHBondContact O-N 3.33Å; G140-R213 PolarHBondContact O-NH1 3.03Å
141	P	86.8	Confident	81	Confident	80 Å²	80	61.8 Å²	61.8	52%	0.519	31%	0.307	S	S	.	.			trans	-74	162	167.3	32.4	-35.7	0	0	0	111.8	L143 L144 C145	P141-L143 VanDerWaalsContact C-N 3.31Å; P141-L143 PolarHBondContact O-N 3.48Å; P141-L144 HydrophobicContact CG-CB 3.86Å; P141-L144 WeakPolarHBondContact O-CB 3.4Å; P141-L144 PolarHBondContact O-N 3.46Å; P141-C145 PolarHBondContact O-N 2.91Å
142	D	86.4	Confident	81.3	Confident	54 Å²	54	58.3 Å²	58.3	29%	0.289	29%	0.289	S	S	.	.	H	α-helix	trans	-54.6	-43	179.3	-178.9	53.8	0	0	0	113.2	L144 C145 R146 S212 R213	D142-L144 PolarHBondContact O-N 3.18Å; D142-C145 WeakPolarHBondContact O-CB 3.27Å; D142-C145 PolarHBondContact O-N 3.49Å; D142-C145 VanDerWaalsContact O-N 3.13Å; D142-R146 PolarHBondContact O-N 3.02Å; D142-R146 IonicContact OD1-CZ 3.19Å; D142-R146 IonicContact OD1-NE 3.14Å; D142-R146 PolarHBondContact OD1-NE 2.88Å; D142-R146 IonicContact OD1-NH2 2.77Å; D142-R146 PolarHBondContact OD1-NH2 2.86Å; D142-R146 IonicContact OD2-CZ 3.13Å; D142-R146 VanDerWaalsContact OD2-CZ 3.25Å; D142-R146 IonicContact OD2-NE 3.74Å; D142-R146 PolarHBondContact OD2-NE 3.23Å; D142-R146 IonicContact OD2-NH2 3.82Å; D142-R146 PolarHBondContact OD2-NH2 3.19Å; D142-S212 WeakPolarHBondContact OD1-CA 3.35Å; D142-S212 WeakPolarHBondContact OD1-CB 3.08Å; D142-R213 HydrophobicContact CB-CB 4.03Å; D142-R213 PolarHBondContact OD1-N 2.93Å
143	L	89.6	Confident	81.8	Confident	137 Å²	137	56.3 Å²	56.3	72%	0.717	28%	0.282	S	S	*	.	H	α-helix	trans	-57.7	-36.3	176.7	-178.4	61.7	0	0	0	112.5	P141 S147	P141-L143 VanDerWaalsContact C-N 3.31Å; P141-L143 PolarHBondContact O-N 3.48Å; L143-S147 VanDerWaalsContact O-CB 3.29Å; L143-S147 WeakPolarHBondContact O-CB 3.31Å; L143-S147 PolarHBondContact O-N 2.87Å; L143-S147 PolarHBondContact O-OG 2.86Å
144	L	87.1	Confident	82.7	Confident	79 Å²	79	56.4 Å²	56.4	41%	0.414	28%	0.282	S	S	.	.	H	α-helix	trans	-69.7	-45.4	177.4	-177	62.5	0	0	0	110.5	F138 P141 D142 R146 S147 V148	F138-L144 HydrophobicContact CE2-CD2 4.45Å; F138-L144 HydrophobicContact CZ-CB 4.35Å; F138-L144 HydrophobicContact CZ-CG 4.44Å; P141-L144 HydrophobicContact CG-CB 3.86Å; P141-L144 WeakPolarHBondContact O-CB 3.4Å; P141-L144 PolarHBondContact O-N 3.46Å; D142-L144 PolarHBondContact O-N 3.18Å; L144-R146 PolarHBondContact O-N 3.35Å; L144-S147 WeakPolarHBondContact CA-OG 3.43Å; L144-S147 PolarHBondContact O-N 2.89Å; L144-S147 PolarHBondContact O-OG 3.22Å; L144-V148 HydrophobicContact CD1-CG2 4.12Å; L144-V148 HydrophobicContact CG-CG2 4.41Å; L144-V148 WeakPolarHBondContact O-CG2 3.49Å; L144-V148 PolarHBondContact O-N 3.08Å
145	C	84.9	Confident	83.3	Confident	0 Å²	0	51.6 Å²	51.6	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-53.2	-53.8	174.4	163.8	0	0	0	0	111.2	F138 P141 D142 S147 V148 K149 C223	F138-C145 HydrophobicContact CE1-CB 3.75Å; F138-C145 HydrophobicContact CZ-CB 3.7Å; P141-C145 PolarHBondContact O-N 2.91Å; D142-C145 WeakPolarHBondContact O-CB 3.27Å; D142-C145 PolarHBondContact O-N 3.49Å; D142-C145 VanDerWaalsContact O-N 3.13Å; C145-S147 PolarHBondContact O-N 3.27Å; C145-V148 PolarHBondContact O-N 3.33Å; C145-K149 PolarHBondContact O-N 3.43Å; C145-C223 VanDerWaalsContact CA-SG 3.53Å; C145-C223 HydrophobicContact CB-CB 3.77Å; C145-C223 WeakPolarHBondContact CB-SG 3.12Å; C145-C223 WeakPolarHBondContact SG-CA 3.18Å; C145-C223 WeakPolarHBondContact SG-CB 3.43Å; C145-C223 CovalentContact SG-SG 2.03Å; C145-C223 PolarHBondContact SG-SG 3.31Å
146	R	88.1	Confident	84	Confident	73 Å²	73	48.9 Å²	48.9	28%	0.275	24%	0.241	S	C	.	.	H	α-helix	trans	-59.3	-45	177	-64.8	-171.8	-157.4	-100.6	-3.5	112.3	D142 L144 V148 Y150 V208 F211	D142-R146 PolarHBondContact O-N 3.02Å; D142-R146 IonicContact OD1-CZ 3.19Å; D142-R146 IonicContact OD1-NE 3.14Å; D142-R146 PolarHBondContact OD1-NE 2.88Å; D142-R146 IonicContact OD1-NH2 2.77Å; D142-R146 PolarHBondContact OD1-NH2 2.86Å; D142-R146 IonicContact OD2-CZ 3.13Å; D142-R146 VanDerWaalsContact OD2-CZ 3.25Å; D142-R146 IonicContact OD2-NE 3.74Å; D142-R146 PolarHBondContact OD2-NE 3.23Å; D142-R146 IonicContact OD2-NH2 3.82Å; D142-R146 PolarHBondContact OD2-NH2 3.19Å; L144-R146 PolarHBondContact O-N 3.35Å; R146-V148 PolarHBondContact O-N 2.99Å; R146-Y150 WeakPolarHBondContact O-CB 3.42Å; R146-Y150 PolarHBondContact O-N 2.86Å; R146-V208 PolarHBondContact NH1-O 2.9Å; R146-F211 WeakPolarHBondContact CG-O 3.26Å
147	S	89.1	Confident	85.2	Confident	39 Å²	39	43.8 Å²	43.8	27%	0.273	22%	0.217	S	C	.	.	H	α-helix	trans	-64.9	-38.1	-179.2	73.7	0	0	0	0	112.9	L143 L144 C145 L151	L143-S147 VanDerWaalsContact O-CB 3.29Å; L143-S147 WeakPolarHBondContact O-CB 3.31Å; L143-S147 PolarHBondContact O-N 2.87Å; L143-S147 PolarHBondContact O-OG 2.86Å; L144-S147 WeakPolarHBondContact CA-OG 3.43Å; L144-S147 PolarHBondContact O-N 2.89Å; L144-S147 PolarHBondContact O-OG 3.22Å; C145-S147 PolarHBondContact O-N 3.27Å; S147-L151 VanDerWaalsContact O-CB 3.26Å; S147-L151 WeakPolarHBondContact O-CB 3.23Å; S147-L151 VanDerWaalsContact O-CG 3.24Å; S147-L151 WeakPolarHBondContact O-CG 3.49Å; S147-L151 PolarHBondContact O-N 3.09Å
148	V	85.6	Confident	86.5	Confident	12 Å²	12	38.3 Å²	38.3	7%	0.073	20%	0.197	C	C	.	.	H	α-helix	trans	-68.5	-52.4	178.8	168	0	0	0	0	109.5	P128 W132 L144 C145 R146 Y150 L151 Q152	P128-V148 HydrophobicContact CB-CG1 3.81Å; P128-V148 HydrophobicContact CG-CG1 3.89Å; P128-V148 HydrophobicContact CG-CG2 4.49Å; W132-V148 HydrophobicContact CZ3-CG1 4.28Å; L144-V148 HydrophobicContact CD1-CG2 4.12Å; L144-V148 HydrophobicContact CG-CG2 4.41Å; L144-V148 WeakPolarHBondContact O-CG2 3.49Å; L144-V148 PolarHBondContact O-N 3.08Å; C145-V148 PolarHBondContact O-N 3.33Å; R146-V148 PolarHBondContact O-N 2.99Å; V148-Y150 VanDerWaalsContact C-N 3.31Å; V148-Y150 PolarHBondContact O-N 3.46Å; V148-L151 PolarHBondContact O-N 3.47Å; V148-Q152 WeakPolarHBondContact O-CB 3.31Å; V148-Q152 PolarHBondContact O-N 2.89Å
149	K	84.6	Confident	87.5	Confident	17 Å²	17	37.4 Å²	37.4	7%	0.074	19%	0.193	C	C	.	.	H	α-helix	trans	-61	-37.5	178.9	-67.6	-66.9	-172.7	-174.3	0	112.7	F46 C145 I153 F211	F46-K149 PolarHBondContact O-NZ 2.9Å; C145-K149 PolarHBondContact O-N 3.43Å; K149-I153 VanDerWaalsContact O-CG1 3.3Å; K149-I153 WeakPolarHBondContact O-CG1 3.48Å; K149-F211 HydrophobicContact CB-CB 4.03Å; K149-F211 HydrophobicContact CB-CD2 4.13Å; K149-F211 HydrophobicContact CB-CG 4.08Å; K149-F211 HydrophobicContact CD-CD1 4.1Å; K149-F211 HydrophobicContact CD-CD2 4.43Å; K149-F211 HydrophobicContact CD-CE1 4.32Å; K149-F211 HydrophobicContact CD-CG 4.16Å; K149-F211 HydrophobicContact CG-CB 3.85Å; K149-F211 HydrophobicContact CG-CD1 4.07Å; K149-F211 HydrophobicContact CG-CD2 4.23Å; K149-F211 HydrophobicContact CG-CG 3.78Å
150	Y	89.3	Confident	88.5	Confident	48 Å²	48	29.1 Å²	29.1	19%	0.188	15%	0.154	C	C	.	.	H	α-helix	trans	-65.5	-54.3	172.6	-179.1	-106.6	0	0	0	112.1	R146 V148 Q152 I153 V154 L201 S204 Q207 V208	R146-Y150 WeakPolarHBondContact O-CB 3.42Å; R146-Y150 PolarHBondContact O-N 2.86Å; V148-Y150 VanDerWaalsContact C-N 3.31Å; V148-Y150 PolarHBondContact O-N 3.46Å; Y150-Q152 PolarHBondContact O-N 3.4Å; Y150-I153 PolarHBondContact O-N 2.99Å; Y150-I153 VanDerWaalsContact O-N 3.11Å; Y150-V154 HydrophobicContact CD1-CG2 3.93Å; Y150-V154 HydrophobicContact CD2-CG2 4.33Å; Y150-V154 HydrophobicContact CE1-CG2 3.53Å; Y150-V154 HydrophobicContact CE2-CG2 3.97Å; Y150-V154 HydrophobicContact CG-CG2 4.3Å; Y150-V154 WeakPolarHBondContact O-CG2 3.45Å; Y150-V154 PolarHBondContact O-N 3.29Å; Y150-L201 HydrophobicContact CE1-CD2 4.46Å; Y150-L201 WeakPolarHBondContact OH-CD2 3.44Å; Y150-L201 PolarHBondContact OH-O 3.03Å; Y150-S204 VanDerWaalsContact CD2-O 3.32Å; Y150-S204 WeakPolarHBondContact CD2-O 3.41Å; Y150-S204 VanDerWaalsContact CE2-CB 3.41Å; Y150-Q207 HydrophobicContact CD2-CB 4.43Å; Y150-V208 HydrophobicContact CD2-CG2 3.69Å; Y150-V208 HydrophobicContact CE2-CG2 4.38Å; Y150-V208 HydrophobicContact CG-CG2 4.07Å
151	L	89.8	Confident	89.3	Confident	50 Å²	50	29.6 Å²	29.6	26%	0.262	15%	0.154	S	C	.	.	H	α-helix	trans	-70.2	-30.3	-174.3	-68.8	171.5	0	0	0	113.5	F124 S147 V148 I153 V154 G155	F124-L151 HydrophobicContact CB-CB 3.8Å; F124-L151 HydrophobicContact CD1-CB 3.85Å; F124-L151 HydrophobicContact CD1-CD1 3.73Å; F124-L151 HydrophobicContact CD1-CG 4.45Å; F124-L151 HydrophobicContact CD2-CB 4.05Å; F124-L151 HydrophobicContact CD2-CD1 4.3Å; F124-L151 HydrophobicContact CE1-CB 4.46Å; F124-L151 HydrophobicContact CE1-CD1 3.49Å; F124-L151 VanDerWaalsContact CE1-CD1 3.49Å; F124-L151 HydrophobicContact CE2-CD1 4.08Å; F124-L151 HydrophobicContact CG-CB 3.61Å; F124-L151 HydrophobicContact CG-CD1 4.13Å; F124-L151 HydrophobicContact CZ-CD1 3.68Å; S147-L151 VanDerWaalsContact O-CB 3.26Å; S147-L151 WeakPolarHBondContact O-CB 3.23Å; S147-L151 VanDerWaalsContact O-CG 3.24Å; S147-L151 WeakPolarHBondContact O-CG 3.49Å; S147-L151 PolarHBondContact O-N 3.09Å; V148-L151 PolarHBondContact O-N 3.47Å; L151-I153 VanDerWaalsContact C-N 3.28Å; L151-I153 PolarHBondContact O-N 2.82Å; L151-V154 PolarHBondContact O-N 3.16Å; L151-G155 PolarHBondContact O-N 2.93Å
152	Q	88.5	Confident	89.6	Confident	9 Å²	9	25.9 Å²	25.9	4%	0.042	13%	0.13	C	C	.	.	H	α-helix	trans	-51.9	-48	167.1	173.8	170.7	8.4	0	0	111.3	L45 F46 Q125 V148 Y150 M156	L45-Q152 PolarHBondContact O-NE2 3.02Å; F46-Q152 HydrophobicContact CD1-CG 4.4Å; F46-Q152 HydrophobicContact CE1-CG 3.63Å; F46-Q152 VanDerWaalsContact CE1-NE2 3.3Å; F46-Q152 HydrophobicContact CZ-CG 3.95Å; Q125-Q152 HydrophobicContact CB-CB 4.5Å; Q125-Q152 HydrophobicContact CB-CG 3.89Å; Q125-Q152 HydrophobicContact CG-CG 3.95Å; V148-Q152 WeakPolarHBondContact O-CB 3.31Å; V148-Q152 PolarHBondContact O-N 2.89Å; Y150-Q152 PolarHBondContact O-N 3.4Å; Q152-M156 PolarHBondContact O-N 3.5Å
153	I	87.1	Confident	89.7	Confident	1 Å²	1	23.4 Å²	23.4	1%	0.005	12%	0.117	C	C	.	.	H	α-helix	trans	-79	-36.2	-177.1	-64.7	-93.7	0	0	0	111.1	F46 K149 Y150 L151 M156 F157 S204 Q207 M240	F46-I153 HydrophobicContact CD1-CD1 3.97Å; F46-I153 HydrophobicContact CE1-CD1 3.26Å; F46-I153 HydrophobicContact CE1-CG1 3.8Å; F46-I153 HydrophobicContact CZ-CD1 4.04Å; K149-I153 VanDerWaalsContact O-CG1 3.3Å; K149-I153 WeakPolarHBondContact O-CG1 3.48Å; Y150-I153 PolarHBondContact O-N 2.99Å; Y150-I153 VanDerWaalsContact O-N 3.11Å; L151-I153 VanDerWaalsContact C-N 3.28Å; L151-I153 PolarHBondContact O-N 2.82Å; I153-M156 WeakPolarHBondContact O-CB 3.25Å; I153-M156 PolarHBondContact O-N 3.03Å; I153-F157 HydrophobicContact CG2-CD2 3.57Å; I153-F157 HydrophobicContact CG2-CE2 3.44Å; I153-F157 VanDerWaalsContact CG2-CE2 3.44Å; I153-F157 WeakPolarHBondContact O-CD2 3.25Å; I153-F157 PolarHBondContact O-N 3.48Å; I153-S204 WeakPolarHBondContact CG2-OG 3.44Å; I153-Q207 HydrophobicContact CB-CG 3.85Å; I153-Q207 HydrophobicContact CD1-CG 4.49Å; I153-Q207 VanDerWaalsContact CD1-NE2 3.32Å; I153-Q207 VanDerWaalsContact CG1-CD 3.47Å; I153-Q207 HydrophobicContact CG1-CG 3.72Å; I153-Q207 HydrophobicContact CG2-CG 3.99Å; I153-M240 HydrophobicContact CD1-CE 3.35Å; I153-M240 HydrophobicContact CD1-SD 4.03Å; I153-M240 HydrophobicContact CG2-CE 4.19Å
154	V	93	Very high	89.9	Confident	4 Å²	4	17.6 Å²	17.6	2%	0.024	9%	0.086	C	C	.	.	H	α-helix	trans	-60	-46.5	172.3	172.8	0	0	0	0	110.9	Y150 L151 M156 F157 A158 W197 L201 S204	Y150-V154 HydrophobicContact CD1-CG2 3.93Å; Y150-V154 HydrophobicContact CD2-CG2 4.33Å; Y150-V154 HydrophobicContact CE1-CG2 3.53Å; Y150-V154 HydrophobicContact CE2-CG2 3.97Å; Y150-V154 HydrophobicContact CG-CG2 4.3Å; Y150-V154 WeakPolarHBondContact O-CG2 3.45Å; Y150-V154 PolarHBondContact O-N 3.29Å; L151-V154 PolarHBondContact O-N 3.16Å; V154-M156 VanDerWaalsContact C-N 3.3Å; V154-M156 PolarHBondContact O-N 3.36Å; V154-F157 PolarHBondContact O-N 3.39Å; V154-A158 WeakPolarHBondContact O-CB 3.28Å; V154-A158 PolarHBondContact O-N 3Å; V154-W197 HydrophobicContact CG1-CZ3 4.26Å; V154-L201 HydrophobicContact CG1-CD2 3.9Å; V154-L201 HydrophobicContact CG2-CD2 4.13Å; V154-S204 WeakPolarHBondContact CA-OG 3.4Å; V154-S204 VanDerWaalsContact CG2-CB 3.48Å; V154-S204 VanDerWaalsContact CG2-OG 3.27Å; V154-S204 WeakPolarHBondContact CG2-OG 3.21Å; V154-S204 PolarHBondContact N-OG 2.87Å
155	G	90.2	Very high	90.1	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-59.6	-42	177.4	0	0	0	0	0	112.3	L151 A158 S159	L151-G155 PolarHBondContact O-N 2.93Å; G155-A158 PolarHBondContact O-N 3.48Å; G155-S159 WeakPolarHBondContact O-CB 3.29Å; G155-S159 PolarHBondContact O-N 2.99Å
156	M	89.2	Confident	90.2	Very high	1 Å²	1	14.6 Å²	14.6	1%	0.005	7%	0.072	C	C	.	.	H	α-helix	trans	-62.9	-53.4	177.5	-171.6	151.7	-59.8	0	0	112.9	F46 Q152 I153 V154 A158 S159 S160 V244 W412	F46-M156 HydrophobicContact CE2-CE 3.44Å; F46-M156 VanDerWaalsContact CE2-CE 3.44Å; F46-M156 HydrophobicContact CE2-SD 3.74Å; F46-M156 HydrophobicContact CZ-CE 3.37Å; F46-M156 HydrophobicContact CZ-SD 3.49Å; F46-M156 WeakPolarHBondContact CZ-SD 3.25Å; Q152-M156 PolarHBondContact O-N 3.5Å; I153-M156 WeakPolarHBondContact O-CB 3.25Å; I153-M156 PolarHBondContact O-N 3.03Å; V154-M156 VanDerWaalsContact C-N 3.3Å; V154-M156 PolarHBondContact O-N 3.36Å; M156-A158 VanDerWaalsContact C-N 3.32Å; M156-A158 PolarHBondContact O-N 3.04Å; M156-S159 PolarHBondContact O-N 3.15Å; M156-S160 PolarHBondContact O-N 3.37Å; M156-S160 VanDerWaalsContact O-N 3.1Å; M156-S160 PolarHBondContact O-OG 2.93Å; M156-V244 HydrophobicContact CG-CG1 3.67Å; M156-V244 HydrophobicContact CG-CG2 4.22Å; M156-V244 HydrophobicContact SD-CG1 4.15Å; M156-W412 HydrophobicContact CE-CH2 3.36Å; M156-W412 HydrophobicContact CE-CZ3 3.75Å; M156-W412 HydrophobicContact CG-CH2 3.77Å; M156-W412 HydrophobicContact CG-CZ2 4.39Å; M156-W412 HydrophobicContact CG-CZ3 4.26Å; M156-W412 HydrophobicContact SD-CH2 3.56Å; M156-W412 VanDerWaalsContact SD-CH2 3.56Å; M156-W412 HydrophobicContact SD-CZ3 3.57Å; M156-W412 VanDerWaalsContact SD-CZ3 3.57Å
157	F	92.9	Very high	90.2	Very high	0 Å²	0	11.1 Å²	11.1	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-63.4	-38.6	175.8	-78	-59.5	0	0	0	111.8	I153 V154 S160 Y161 A200 L203 S204 M240 A243 V244	I153-F157 HydrophobicContact CG2-CD2 3.57Å; I153-F157 HydrophobicContact CG2-CE2 3.44Å; I153-F157 VanDerWaalsContact CG2-CE2 3.44Å; I153-F157 WeakPolarHBondContact O-CD2 3.25Å; I153-F157 PolarHBondContact O-N 3.48Å; V154-F157 PolarHBondContact O-N 3.39Å; F157-S160 PolarHBondContact O-N 3.47Å; F157-Y161 HydrophobicContact CB-CD2 4.12Å; F157-Y161 HydrophobicContact CB-CE2 4.31Å; F157-Y161 HydrophobicContact CD1-CD2 4.22Å; F157-Y161 AromaticContact CD1-CE2 3.61Å; F157-Y161 HydrophobicContact CD1-CE2 3.61Å; F157-Y161 HydrophobicContact CE1-CE2 4.32Å; F157-Y161 HydrophobicContact CG-CE2 4.32Å; F157-Y161 WeakPolarHBondContact O-CB 3.3Å; F157-Y161 VanDerWaalsContact O-CD2 3.22Å; F157-Y161 WeakPolarHBondContact O-CD2 3.34Å; F157-Y161 PolarHBondContact O-N 3.46Å; F157-A200 HydrophobicContact CB-CB 3.64Å; F157-L203 HydrophobicContact CD1-CD1 4.44Å; F157-L203 HydrophobicContact CD2-CB 4.1Å; F157-L203 HydrophobicContact CE1-CB 4.22Å; F157-L203 HydrophobicContact CE1-CD1 4.38Å; F157-L203 HydrophobicContact CE2-CB 3.79Å; F157-L203 HydrophobicContact CG-CB 4.45Å; F157-L203 HydrophobicContact CZ-CB 3.86Å; F157-S204 WeakPolarHBondContact CD2-OG 3.11Å; F157-M240 HydrophobicContact CE2-CE 4.23Å; F157-M240 HydrophobicContact CE2-SD 4.26Å; F157-M240 HydrophobicContact CZ-CE 4.11Å; F157-M240 HydrophobicContact CZ-SD 4.03Å; F157-A243 HydrophobicContact CE1-CB 3.66Å; F157-A243 HydrophobicContact CZ-CB 4.02Å; F157-V244 HydrophobicContact CD1-CG2 3.66Å; F157-V244 HydrophobicContact CE1-CB 4.3Å; F157-V244 HydrophobicContact CE1-CG2 3.33Å; F157-V244 HydrophobicContact CE2-CG2 4.46Å; F157-V244 HydrophobicContact CG-CG2 4.37Å; F157-V244 HydrophobicContact CZ-CG2 3.78Å
158	A	94.5	Very high	90.2	Very high	0 Å²	0	11.2 Å²	11.2	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-62	-47.1	178.1	0	0	0	0	0	110.9	A117 V154 G155 M156 M162 W197 A200	A117-A158 HydrophobicContact CB-CB 3.79Å; V154-A158 WeakPolarHBondContact O-CB 3.28Å; V154-A158 PolarHBondContact O-N 3Å; G155-A158 PolarHBondContact O-N 3.48Å; M156-A158 VanDerWaalsContact C-N 3.32Å; M156-A158 PolarHBondContact O-N 3.04Å; A158-M162 WeakPolarHBondContact O-CB 3.45Å; A158-M162 WeakPolarHBondContact O-CG 3.29Å; A158-M162 PolarHBondContact O-N 2.93Å; A158-W197 HydrophobicContact CB-CE3 4.1Å; A158-W197 HydrophobicContact CB-CH2 4.07Å; A158-W197 HydrophobicContact CB-CZ3 3.82Å; A158-A200 HydrophobicContact CB-CB 4.02Å
159	S	91.7	Very high	90.1	Very high	1 Å²	1	11.9 Å²	11.9	1%	0.007	6%	0.061	C	C	.	.	H	α-helix	trans	-61.1	-47.6	177.8	-165.9	0	0	0	0	111.1	L114 D118 G155 M156 M162 I163	L114-S159 WeakPolarHBondContact CD1-O 3.19Å; D118-S159 PolarHBondContact OD1-OG 3.41Å; G155-S159 WeakPolarHBondContact O-CB 3.29Å; G155-S159 PolarHBondContact O-N 2.99Å; M156-S159 PolarHBondContact O-N 3.15Å; S159-M162 PolarHBondContact O-N 3.07Å; S159-I163 WeakPolarHBondContact O-CG1 3.5Å; S159-I163 PolarHBondContact O-N 3.36Å; S159-I163 VanDerWaalsContact O-N 3.17Å
160	S	92.6	Very high	90	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-62.4	-50.3	177.2	-63.2	0	0	0	0	113.7	M156 F157 M162 I163 V164 Y408	M156-S160 PolarHBondContact O-N 3.37Å; M156-S160 VanDerWaalsContact O-N 3.1Å; M156-S160 PolarHBondContact O-OG 2.93Å; F157-S160 PolarHBondContact O-N 3.47Å; S160-M162 VanDerWaalsContact C-N 3.34Å; S160-M162 PolarHBondContact O-N 2.9Å; S160-I163 WeakPolarHBondContact O-CB 3.41Å; S160-I163 PolarHBondContact O-N 2.99Å; S160-V164 WeakPolarHBondContact O-CG2 3.48Å; S160-V164 PolarHBondContact O-N 2.88Å; S160-Y408 PolarHBondContact OG-OH 2.92Å
161	Y	94.6	Very high	89.8	Confident	16 Å²	16	10.7 Å²	10.7	6%	0.063	6%	0.056	C	C	.	.	H	α-helix	trans	-72.7	-24.1	-179.4	-74	-63.9	0	0	0	113.3	F157 V164 A165 L199 L203 A243 P248	F157-Y161 HydrophobicContact CB-CD2 4.12Å; F157-Y161 HydrophobicContact CB-CE2 4.31Å; F157-Y161 HydrophobicContact CD1-CD2 4.22Å; F157-Y161 AromaticContact CD1-CE2 3.61Å; F157-Y161 HydrophobicContact CD1-CE2 3.61Å; F157-Y161 HydrophobicContact CE1-CE2 4.32Å; F157-Y161 HydrophobicContact CG-CE2 4.32Å; F157-Y161 WeakPolarHBondContact O-CB 3.3Å; F157-Y161 VanDerWaalsContact O-CD2 3.22Å; F157-Y161 WeakPolarHBondContact O-CD2 3.34Å; F157-Y161 PolarHBondContact O-N 3.46Å; Y161-V164 HydrophobicContact CD1-CG2 4.38Å; Y161-V164 PolarHBondContact O-N 3.38Å; Y161-A165 VanDerWaalsContact O-CB 3.26Å; Y161-A165 WeakPolarHBondContact O-CB 3.42Å; Y161-A165 PolarHBondContact O-N 2.93Å; Y161-L199 HydrophobicContact CD1-CD1 4.39Å; Y161-L199 HydrophobicContact CD2-CB 4.33Å; Y161-L199 HydrophobicContact CE1-CD1 4.48Å; Y161-L199 HydrophobicContact CE2-CB 4.48Å; Y161-L203 HydrophobicContact CD2-CD1 4.48Å; Y161-L203 HydrophobicContact CE2-CD1 3.45Å; Y161-L203 VanDerWaalsContact CE2-CD1 3.45Å; Y161-L203 WeakPolarHBondContact OH-CD1 3.36Å; Y161-A243 PolarHBondContact OH-O 3.25Å; Y161-A243 VanDerWaalsContact OH-O 3.04Å; Y161-P248 HydrophobicContact CE1-CG 4.2Å
162	M	92.5	Very high	89.5	Confident	3 Å²	3	13 Å²	13	2%	0.015	7%	0.066	C	C	.	.	H	α-helix	trans	-68	-35.7	169.5	-78.4	-62.8	-52.6	0	0	112.2	F110 N113 L114 A158 S159 S160 M166 V193 A196	F110-M162 HydrophobicContact CB-CE 4.22Å; F110-M162 HydrophobicContact CD1-CE 3.68Å; F110-M162 HydrophobicContact CG-CE 4.44Å; F110-M162 WeakPolarHBondContact O-CE 3.45Å; N113-M162 HydrophobicContact CB-CE 3.32Å; N113-M162 HydrophobicContact CB-SD 3.89Å; L114-M162 HydrophobicContact CD1-CB 3.62Å; A158-M162 WeakPolarHBondContact O-CB 3.45Å; A158-M162 WeakPolarHBondContact O-CG 3.29Å; A158-M162 PolarHBondContact O-N 2.93Å; S159-M162 PolarHBondContact O-N 3.07Å; S160-M162 VanDerWaalsContact C-N 3.34Å; S160-M162 PolarHBondContact O-N 2.9Å; M162-M166 VanDerWaalsContact O-CB 3.31Å; M162-M166 WeakPolarHBondContact O-CB 3.47Å; M162-M166 PolarHBondContact O-N 3.46Å; M162-V193 HydrophobicContact CE-CG2 4.35Å; M162-V193 HydrophobicContact SD-CG1 4.19Å; M162-V193 HydrophobicContact SD-CG2 4.45Å; M162-A196 HydrophobicContact CG-CB 4.48Å; M162-A196 HydrophobicContact SD-CB 4.04Å
163	I	90.1	Very high	89	Confident	2 Å²	2	14.6 Å²	14.6	1%	0.01	8%	0.08	C	C	.	.	H	α-helix	trans	-67	-41.3	171	-67.8	166.8	0	0	0	111	L114 S159 S160 M166 T167 I252 I404 Y408	L114-I163 HydrophobicContact CD1-CG1 4.17Å; L114-I163 HydrophobicContact CD2-CG1 4.24Å; S159-I163 WeakPolarHBondContact O-CG1 3.5Å; S159-I163 PolarHBondContact O-N 3.36Å; S159-I163 VanDerWaalsContact O-N 3.17Å; S160-I163 WeakPolarHBondContact O-CB 3.41Å; S160-I163 PolarHBondContact O-N 2.99Å; I163-M166 PolarHBondContact O-N 3.33Å; I163-T167 WeakPolarHBondContact O-CG2 3.44Å; I163-T167 PolarHBondContact O-N 2.7Å; I163-T167 PolarHBondContact O-OG1 2.9Å; I163-I252 HydrophobicContact CG2-CD1 3.68Å; I163-I252 HydrophobicContact CG2-CG1 4.39Å; I163-I404 HydrophobicContact CD1-CG2 4.33Å; I163-I404 HydrophobicContact CG1-CG2 4.24Å; I163-I404 HydrophobicContact CG2-CG2 3.5Å; I163-I404 VanDerWaalsContact CG2-CG2 3.5Å; I163-Y408 HydrophobicContact CD1-CD2 3.83Å; I163-Y408 HydrophobicContact CD1-CE2 4.39Å
164	V	93.1	Very high	88.6	Confident	14 Å²	14	15.5 Å²	15.5	9%	0.085	9%	0.085	C	C	.	.	H	α-helix	trans	-59.8	-51.1	172.5	176.1	0	0	0	0	110.7	S160 Y161 M166 T167 V168 P248 I251 I252	S160-V164 WeakPolarHBondContact O-CG2 3.48Å; S160-V164 PolarHBondContact O-N 2.88Å; Y161-V164 HydrophobicContact CD1-CG2 4.38Å; Y161-V164 PolarHBondContact O-N 3.38Å; V164-M166 VanDerWaalsContact C-N 3.32Å; V164-M166 PolarHBondContact O-N 2.93Å; V164-T167 PolarHBondContact O-N 2.87Å; V164-T167 VanDerWaalsContact O-N 3.16Å; V164-T167 PolarHBondContact O-OG1 3.49Å; V164-V168 HydrophobicContact CG1-CG2 4.22Å; V164-V168 WeakPolarHBondContact O-CB 3.32Å; V164-V168 VanDerWaalsContact O-CG2 3.31Å; V164-V168 WeakPolarHBondContact O-CG2 3.46Å; V164-V168 PolarHBondContact O-N 3.43Å; V164-P248 HydrophobicContact CG2-CB 3.61Å; V164-P248 HydrophobicContact CG2-CG 4.23Å; V164-I251 HydrophobicContact CG1-CB 4.3Å; V164-I251 HydrophobicContact CG1-CD1 4.31Å; V164-I251 HydrophobicContact CG1-CG2 3.71Å; V164-I252 HydrophobicContact CG2-CD1 4.05Å; V164-I252 HydrophobicContact CG2-CG1 4.05Å
165	A	91	Very high	88	Confident	10 Å²	10	16.4 Å²	16.4	8%	0.083	9%	0.091	C	C	.	.	H	α-helix	trans	-59.4	-41.8	-179.7	0	0	0	0	0	112.2	F110 Y161 D169 P192 A196	F110-A165 HydrophobicContact CD1-CB 4.39Å; F110-A165 HydrophobicContact CE1-CB 3.8Å; Y161-A165 VanDerWaalsContact O-CB 3.26Å; Y161-A165 WeakPolarHBondContact O-CB 3.42Å; Y161-A165 PolarHBondContact O-N 2.93Å; A165-D169 WeakPolarHBondContact O-CB 3.49Å; A165-D169 PolarHBondContact O-N 2.9Å; A165-P192 HydrophobicContact CB-CB 4.25Å; A165-A196 HydrophobicContact CB-CB 4.27Å
166	M	87.2	Confident	87.4	Confident	6 Å²	6	18.4 Å²	18.4	3%	0.03	10%	0.104	C	C	.	.	H	α-helix	trans	-63.8	-46.3	174	179.5	176.3	168.3	0	0	112	M107 F110 M162 I163 V164 V168 D169 R170 M400 I404	M107-M166 HydrophobicContact CE-CE 4.08Å; F110-M166 HydrophobicContact CB-CB 4.38Å; F110-M166 HydrophobicContact CD1-CB 4.42Å; F110-M166 HydrophobicContact CG-CB 4.29Å; M162-M166 VanDerWaalsContact O-CB 3.31Å; M162-M166 WeakPolarHBondContact O-CB 3.47Å; M162-M166 PolarHBondContact O-N 3.46Å; I163-M166 PolarHBondContact O-N 3.33Å; V164-M166 VanDerWaalsContact C-N 3.32Å; V164-M166 PolarHBondContact O-N 2.93Å; M166-V168 PolarHBondContact O-N 2.91Å; M166-D169 PolarHBondContact O-N 2.96Å; M166-R170 VanDerWaalsContact O-CG 3.31Å; M166-R170 WeakPolarHBondContact O-CG 3.21Å; M166-R170 PolarHBondContact O-N 3.5Å; M166-M400 HydrophobicContact CE-CE 3.89Å; M166-M400 HydrophobicContact CE-SD 4.03Å; M166-I404 HydrophobicContact CE-CD1 3.88Å; M166-I404 HydrophobicContact SD-CD1 4.23Å
167	T	88	Confident	86.4	Confident	1 Å²	1	21.8 Å²	21.8	1%	0.006	13%	0.126	C	C	.	.	H	α-helix	trans	-69.8	-31.5	-179.2	51.4	0	0	0	0	113	I163 V164 R170 H171 I252 T401	I163-T167 WeakPolarHBondContact O-CG2 3.44Å; I163-T167 PolarHBondContact O-N 2.7Å; I163-T167 PolarHBondContact O-OG1 2.9Å; V164-T167 PolarHBondContact O-N 2.87Å; V164-T167 VanDerWaalsContact O-N 3.16Å; V164-T167 PolarHBondContact O-OG1 3.49Å; T167-R170 PolarHBondContact O-N 3.01Å; T167-H171 WeakPolarHBondContact O-CB 3.33Å; T167-H171 PolarHBondContact O-N 3.42Å; T167-I252 HydrophobicContact CG2-CG2 4.45Å; T167-T401 HydrophobicContact CG2-CG2 4.25Å
168	V	88.1	Confident	84.9	Confident	40 Å²	40	28.3 Å²	28.3	24%	0.242	16%	0.16	C	C	.	.	H	α-helix	trans	-68.6	-43.2	171.8	169.4	0	0	0	0	111.7	V164 M166 R170 H171 H172 I251	V164-V168 HydrophobicContact CG1-CG2 4.22Å; V164-V168 WeakPolarHBondContact O-CB 3.32Å; V164-V168 VanDerWaalsContact O-CG2 3.31Å; V164-V168 WeakPolarHBondContact O-CG2 3.46Å; V164-V168 PolarHBondContact O-N 3.43Å; M166-V168 PolarHBondContact O-N 2.91Å; V168-R170 VanDerWaalsContact C-N 3.34Å; V168-R170 PolarHBondContact O-N 3.19Å; V168-H171 WeakPolarHBondContact O-CB 3.27Å; V168-H171 PolarHBondContact O-N 2.9Å; V168-H171 VanDerWaalsContact O-N 3.15Å; V168-H172 PolarHBondContact O-CD2 3.18Å; V168-H172 PolarHBondContact O-N 3.4Å; V168-I251 HydrophobicContact CG2-CG2 4.18Å
169	D	84.6	Confident	83.4	Confident	26 Å²	26	33.7 Å²	33.7	14%	0.139	19%	0.185	C	C	.	.	H	α-helix	trans	-57.4	-45.1	171.6	159.1	96.7	0	0	0	111.6	F110 A165 M166 H171 H172 A173	F110-D169 HydrophobicContact CE2-CB 3.63Å; F110-D169 HydrophobicContact CZ-CB 3.83Å; A165-D169 WeakPolarHBondContact O-CB 3.49Å; A165-D169 PolarHBondContact O-N 2.9Å; M166-D169 PolarHBondContact O-N 2.96Å; D169-H171 VanDerWaalsContact C-N 3.35Å; D169-H171 PolarHBondContact O-N 2.88Å; D169-H172 PolarHBondContact O-N 3.1Å; D169-A173 WeakPolarHBondContact O-CB 3.07Å; D169-A173 PolarHBondContact O-N 3.24Å
170	R	82	Confident	81.7	Confident	30 Å²	30	36.2 Å²	36.2	11%	0.113	21%	0.206	C	C	.	.	H	α-helix	trans	-62.7	-39.5	174.2	-63.6	-60.3	99.5	159.6	3.5	112.2	M107 M166 T167 V168 A173 I174 I259 T397 T401	M107-R170 PolarHBondContact SD-NH1 3.22Å; M166-R170 VanDerWaalsContact O-CG 3.31Å; M166-R170 WeakPolarHBondContact O-CG 3.21Å; M166-R170 PolarHBondContact O-N 3.5Å; T167-R170 PolarHBondContact O-N 3.01Å; V168-R170 VanDerWaalsContact C-N 3.34Å; V168-R170 PolarHBondContact O-N 3.19Å; R170-A173 PolarHBondContact O-N 2.6Å; R170-I174 WeakPolarHBondContact O-CB 3.32Å; R170-I174 VanDerWaalsContact O-CG1 3.31Å; R170-I174 WeakPolarHBondContact O-CG1 3.5Å; R170-I174 PolarHBondContact O-N 2.9Å; R170-I174 VanDerWaalsContact O-N 3.09Å; R170-I259 HydrophobicContact CB-CD1 4.42Å; R170-T397 HydrophobicContact CG-CG2 4.2Å; R170-T401 HydrophobicContact CB-CG2 4.22Å; R170-T401 HydrophobicContact CG-CG2 3.82Å
171	H	84.8	Confident	80	Confident	10 Å²	10	45.8 Å²	45.8	5%	0.046	24%	0.244	C	C	.	.	H	α-helix	trans	-61.8	-47.6	176.1	174	54.2	0	0	0	111.9	T167 V168 D169 A173 I174 C175 C255 R258 I259	T167-H171 WeakPolarHBondContact O-CB 3.33Å; T167-H171 PolarHBondContact O-N 3.42Å; V168-H171 WeakPolarHBondContact O-CB 3.27Å; V168-H171 PolarHBondContact O-N 2.9Å; V168-H171 VanDerWaalsContact O-N 3.15Å; D169-H171 VanDerWaalsContact C-N 3.35Å; D169-H171 PolarHBondContact O-N 2.88Å; H171-A173 PolarHBondContact O-N 3.27Å; H171-I174 PolarHBondContact O-N 3.3Å; H171-C175 VanDerWaalsContact CE1-CB 3.48Å; H171-C175 WeakPolarHBondContact CE1-CB 3.22Å; H171-C175 PolarHBondContact ND1-SG 3.34Å; H171-C175 VanDerWaalsContact O-CB 3.3Å; H171-C175 WeakPolarHBondContact O-CB 3.39Å; H171-C175 PolarHBondContact O-N 2.95Å; H171-C255 HydrophobicContact CB-CB 4.2Å; H171-R258 PolarHBondContact CE1-NE 3.22Å; H171-R258 PolarHBondContact NE2-NH1 3.3Å; H171-R258 VanDerWaalsContact NE2-NH1 3.19Å; H171-I259 HydrophobicContact CB-CD1 4.04Å; H171-I259 HydrophobicContact CB-CG1 4.17Å
172	H	83	Confident	78.2	Confident	100 Å²	100	55.2 Å²	55.2	46%	0.463	28%	0.279	S	S	.	.	H	α-helix	trans	-64.1	-41.1	177	-72.9	-63.5	0	0	0	112.7	V168 D169 I174 C176	V168-H172 PolarHBondContact O-CD2 3.18Å; V168-H172 PolarHBondContact O-N 3.4Å; D169-H172 PolarHBondContact O-N 3.1Å; H172-I174 VanDerWaalsContact C-N 3.3Å; H172-I174 PolarHBondContact O-N 3.23Å; H172-C176 CarbonylContact O-C 3.57Å; H172-C176 WeakPolarHBondContact O-CA 3.37Å; H172-C176 WeakPolarHBondContact O-CB 3.41Å; H172-C176 PolarHBondContact O-N 3.03Å
173	A	79.2	Confident	76.4	Confident	41 Å²	41	59.9 Å²	59.9	34%	0.339	31%	0.308	S	S	.	.	H	α-helix	trans	-66.3	-28.7	179.7	0	0	0	0	0	113.9	D169 R170 H171	D169-A173 WeakPolarHBondContact O-CB 3.07Å; D169-A173 PolarHBondContact O-N 3.24Å; R170-A173 PolarHBondContact O-N 2.6Å; H171-A173 PolarHBondContact O-N 3.27Å
174	I	79	Confident	74.5	Confident	21 Å²	21	62.4 Å²	62.4	11%	0.108	34%	0.335	C	S	.	.	H	α-helix	trans	-95.8	-48.4	-178.5	-64.8	168.6	0	0	0	111.5	R170 H171 H172 I259 I263 M394 V398	R170-I174 WeakPolarHBondContact O-CB 3.32Å; R170-I174 VanDerWaalsContact O-CG1 3.31Å; R170-I174 WeakPolarHBondContact O-CG1 3.5Å; R170-I174 PolarHBondContact O-N 2.9Å; R170-I174 VanDerWaalsContact O-N 3.09Å; H171-I174 PolarHBondContact O-N 3.3Å; H172-I174 VanDerWaalsContact C-N 3.3Å; H172-I174 PolarHBondContact O-N 3.23Å; I174-I259 HydrophobicContact CD1-CG2 3.96Å; I174-I263 HydrophobicContact CG2-CD1 4.23Å; I174-I263 HydrophobicContact CG2-CG1 4.05Å; I174-M394 HydrophobicContact CG1-SD 4.04Å; I174-V398 HydrophobicContact CD1-CG2 3.72Å
175	C	80.8	Confident	72.5	Confident	23 Å²	23	65.2 Å²	65.2	16%	0.155	36%	0.359	C	S	.	.	H	α-helix	trans	-93.2	-10	-171.8	-56.3	0	0	0	0	114.4	H171 P177 E262	H171-C175 VanDerWaalsContact CE1-CB 3.48Å; H171-C175 WeakPolarHBondContact CE1-CB 3.22Å; H171-C175 PolarHBondContact ND1-SG 3.34Å; H171-C175 VanDerWaalsContact O-CB 3.3Å; H171-C175 WeakPolarHBondContact O-CB 3.39Å; H171-C175 PolarHBondContact O-N 2.95Å; C175-P177 VanDerWaalsContact C-CD 3.49Å; C175-E262 HydrophobicContact CB-CG 4.44Å
176	C	76.5	Confident	70.4	Confident	42 Å²	42	72.4 Å²	72.4	28%	0.284	39%	0.393	S	S	.	.			trans	-135	48.4	179.4	-58.9	0	0	0	0	112.9	H172 L178 Q179 A180	H172-C176 CarbonylContact O-C 3.57Å; H172-C176 WeakPolarHBondContact O-CA 3.37Å; H172-C176 WeakPolarHBondContact O-CB 3.41Å; H172-C176 PolarHBondContact O-N 3.03Å; C176-L178 VanDerWaalsContact C-N 3.31Å; C176-L178 PolarHBondContact O-N 2.95Å; C176-Q179 HydrophobicContact CB-CB 4.09Å; C176-Q179 WeakPolarHBondContact O-CB 3.37Å; C176-Q179 PolarHBondContact O-N 3.48Å; C176-A180 PolarHBondContact O-N 2.83Å
177	P	69.2	Low	68.7	Low	71 Å²	71	77.1 Å²	77.1	46%	0.461	43%	0.427	S	S	.	.	H	α-helix	trans	-60.7	-35.9	-171.1	25.5	-35.2	0	0	0	113.4	C175 Q179 A180 Y181	C175-P177 VanDerWaalsContact C-CD 3.49Å; P177-Q179 VanDerWaalsContact C-N 3.32Å; P177-Q179 PolarHBondContact O-N 3.21Å; P177-A180 PolarHBondContact O-N 3.07Å; P177-Y181 PolarHBondContact O-N 3.22Å
178	L	59.5	Low	67.6	Low	137 Å²	137	86 Å²	86	72%	0.717	46%	0.46	S	S	*	.	H	α-helix	trans	-67.2	-31.1	176.1	-67.2	175	0	0	0	112.8	C176 R182	C176-L178 VanDerWaalsContact C-N 3.31Å; C176-L178 PolarHBondContact O-N 2.95Å; L178-R182 WeakPolarHBondContact O-CB 3.39Å; L178-R182 PolarHBondContact O-N 3.45Å
179	Q	63.6	Low	66.6	Low	113 Å²	113	90.1 Å²	90.1	53%	0.528	47%	0.471	S	S	.	.	H	α-helix	trans	-75.3	-41.6	174.5	-164.9	67.6	4.3	0	0	110.6	C176 P177 Y181 R182 V183	C176-Q179 HydrophobicContact CB-CB 4.09Å; C176-Q179 WeakPolarHBondContact O-CB 3.37Å; C176-Q179 PolarHBondContact O-N 3.48Å; P177-Q179 VanDerWaalsContact C-N 3.32Å; P177-Q179 PolarHBondContact O-N 3.21Å; Q179-Y181 PolarHBondContact O-N 3.37Å; Q179-R182 PolarHBondContact O-N 3.22Å; Q179-V183 HydrophobicContact CG-CG2 4.07Å; Q179-V183 VanDerWaalsContact O-CB 3.27Å; Q179-V183 WeakPolarHBondContact O-CB 3.5Å; Q179-V183 WeakPolarHBondContact O-CG2 3.5Å; Q179-V183 PolarHBondContact O-N 2.87Å
180	A	57.4	Low	66.3	Low	54 Å²	54	93.4 Å²	93.4	45%	0.446	49%	0.489	S	S	.	.	H	α-helix	trans	-59.6	-31.6	173.6	0	0	0	0	0	112.7	C176 P177	C176-A180 PolarHBondContact O-N 2.83Å; P177-A180 PolarHBondContact O-N 3.07Å
181	Y	56.7	Low	66.5	Low	202 Å²	202	94.6 Å²	94.6	79%	0.792	50%	0.5	S	S	*	.	H	α-helix	trans	-78.3	-50.2	173.4	-168.8	-103.4	0	0	0	112.7	P177 Q179 V183 G184	P177-Y181 PolarHBondContact O-N 3.22Å; Q179-Y181 PolarHBondContact O-N 3.37Å; Y181-V183 VanDerWaalsContact C-N 3.27Å; Y181-V183 PolarHBondContact O-N 3.45Å; Y181-G184 PolarHBondContact O-N 3.38Å
182	R	55.1	Low	66.6	Low	213 Å²	213	96.3 Å²	96.3	80%	0.804	51%	0.511	S	S	*	.	H	α-helix	trans	-61.8	-29.1	178.7	-84.1	-175.1	173.5	166	-1.9	114.1	L178 Q179 G184	L178-R182 WeakPolarHBondContact O-CB 3.39Å; L178-R182 PolarHBondContact O-N 3.45Å; Q179-R182 PolarHBondContact O-N 3.22Å; R182-G184 PolarHBondContact O-N 3.17Å
183	V	55.1	Low	67	Low	101 Å²	101	92 Å²	92	61%	0.612	49%	0.492	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.2	6.7	179.9	175.4	0	0	0	0	112.8	Q179 Y181 A185	Q179-V183 HydrophobicContact CG-CG2 4.07Å; Q179-V183 VanDerWaalsContact O-CB 3.27Å; Q179-V183 WeakPolarHBondContact O-CB 3.5Å; Q179-V183 WeakPolarHBondContact O-CG2 3.5Å; Q179-V183 PolarHBondContact O-N 2.87Å; Y181-V183 VanDerWaalsContact C-N 3.27Å; Y181-V183 PolarHBondContact O-N 3.45Å; V183-A185 PolarHBondContact O-N 3.46Å; V183-A185 VanDerWaalsContact O-N 3.16Å
184	G	49.7	Very low	67.5	Low	56 Å²	56	95 Å²	95	58%	0.577	50%	0.502	S	S	*	.			trans	55.5	51.1	138.3	0	0	0	0	0	116.8	Y181 R182	Y181-G184 PolarHBondContact O-N 3.38Å; R182-G184 PolarHBondContact O-N 3.17Å
185	A	51.3	Low	68.2	Low	72 Å²	72	97.6 Å²	97.6	60%	0.595	52%	0.518	S	S	*	.	S	Bend	trans	28.7	95.1	162.4	0	0	0	0	0	118.3	V183	V183-A185 PolarHBondContact O-N 3.46Å; V183-A185 VanDerWaalsContact O-N 3.16Å
186	M	47.2	Very low	68.9	Low	162 Å²	162	96.7 Å²	96.7	80%	0.798	51%	0.512	S	S	*	.	S	Bend		-179.8	-42.6	117.5	-99.1	-59.1	178.5	0	0	113.9	R188 W189	M186-R188 PolarHBondContact O-N 2.77Å; M186-W189 VanDerWaalsContact O-CD1 3.32Å
187	S	51.5	Low	69.8	Low	105 Å²	105	97.3 Å²	97.3	73%	0.734	51%	0.509	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.7	-27.3	-154.9	175.5	0	0	0	0	117.3
188	R	65.3	Low	71.1	Confident	188 Å²	188	96.2 Å²	96.2	71%	0.709	51%	0.505	S	S	*	.	T	Hydrogen-bonded Turn	trans	-126.4	15.8	-162.5	-69.7	-165.2	176.2	103.7	-0.1	117.5	M186 N190 T191	M186-R188 PolarHBondContact O-N 2.77Å; R188-N190 PolarHBondContact O-N 3.35Å; R188-T191 WeakPolarHBondContact CB-OG1 3.11Å; R188-T191 WeakPolarHBondContact CG-OG1 3.31Å; R188-T191 VanDerWaalsContact O-CB 3.28Å; R188-T191 WeakPolarHBondContact O-CB 3.48Å; R188-T191 PolarHBondContact O-N 3.45Å; R188-T191 PolarHBondContact O-OG1 3.24Å
189	W	67.1	Low	72.9	Confident	126 Å²	126	93.1 Å²	93.1	48%	0.477	49%	0.489	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.3	-29.8	175.8	-58.8	104.3	0	0	0	113.6	P106 M186	P106-W189 HydrophobicContact CB-CE3 4.21Å; M186-W189 VanDerWaalsContact O-CD1 3.32Å
190	N	79.1	Confident	74.4	Confident	94 Å²	94	87.7 Å²	87.7	50%	0.503	46%	0.464	S	S	.	.	T	Hydrogen-bonded Turn	trans	-82.5	-16.1	176.8	-62.9	4.3	0	0	0	112.9	L109 R188 V193 I194	L109-N190 WeakPolarHBondContact CD2-OD1 3.41Å; R188-N190 PolarHBondContact O-N 3.35Å; N190-V193 WeakPolarHBondContact O-CB 3.19Å; N190-V193 PolarHBondContact O-N 2.94Å; N190-V193 VanDerWaalsContact O-N 3.09Å; N190-I194 HydrophobicContact CB-CD1 3.92Å; N190-I194 HydrophobicContact CB-CG1 4.46Å; N190-I194 WeakPolarHBondContact O-CG1 3.29Å; N190-I194 PolarHBondContact O-N 3.27Å
191	T	84.7	Confident	76.3	Confident	56 Å²	56	88.7 Å²	88.7	34%	0.344	46%	0.461	S	S	.	.	H	α-helix	trans	-55	-47.4	-176.6	-59.7	0	0	0	0	114	R188 V193 I194 V195	R188-T191 WeakPolarHBondContact CB-OG1 3.11Å; R188-T191 WeakPolarHBondContact CG-OG1 3.31Å; R188-T191 VanDerWaalsContact O-CB 3.28Å; R188-T191 WeakPolarHBondContact O-CB 3.48Å; R188-T191 PolarHBondContact O-N 3.45Å; R188-T191 PolarHBondContact O-OG1 3.24Å; T191-V193 VanDerWaalsContact C-N 3.27Å; T191-V193 PolarHBondContact O-N 2.87Å; T191-I194 PolarHBondContact O-N 2.84Å; T191-V195 HydrophobicContact CG2-CG2 4.24Å; T191-V195 WeakPolarHBondContact O-CB 3.29Å; T191-V195 VanDerWaalsContact O-CG2 3.3Å; T191-V195 WeakPolarHBondContact O-CG2 3.3Å; T191-V195 PolarHBondContact O-N 3.47Å
192	P	87.8	Confident	78.2	Confident	45 Å²	45	83.4 Å²	83.4	29%	0.292	45%	0.45	S	S	.	.	H	α-helix	trans	-61.8	-32.4	176.5	23.3	-34.7	0	0	0	113.5	F110 A165 A196	F110-P192 HydrophobicContact CE1-CB 4.26Å; F110-P192 HydrophobicContact CE1-CG 4.21Å; F110-P192 HydrophobicContact CZ-CB 4.17Å; F110-P192 HydrophobicContact CZ-CG 3.77Å; A165-P192 HydrophobicContact CB-CB 4.25Å; P192-A196 WeakPolarHBondContact O-CB 3.31Å; P192-A196 PolarHBondContact O-N 3.06Å
193	V	90.2	Very high	80	Confident	10 Å²	10	74.7 Å²	74.7	6%	0.061	42%	0.419	C	S	.	.	H	α-helix	trans	-72.2	-44.1	175.4	176.6	0	0	0	0	111.1	L109 F110 N113 M162 N190 T191 V195 A196 W197	L109-V193 HydrophobicContact CD2-CG2 4.1Å; L109-V193 HydrophobicContact CG-CG2 4.28Å; F110-V193 HydrophobicContact CD1-CG2 3.77Å; F110-V193 HydrophobicContact CE1-CG2 3.57Å; F110-V193 HydrophobicContact CZ-CG2 4.37Å; N113-V193 HydrophobicContact CB-CG1 4.31Å; N113-V193 WeakPolarHBondContact OD1-CG1 3.33Å; M162-V193 HydrophobicContact CE-CG2 4.35Å; M162-V193 HydrophobicContact SD-CG1 4.19Å; M162-V193 HydrophobicContact SD-CG2 4.45Å; N190-V193 WeakPolarHBondContact O-CB 3.19Å; N190-V193 PolarHBondContact O-N 2.94Å; N190-V193 VanDerWaalsContact O-N 3.09Å; T191-V193 VanDerWaalsContact C-N 3.27Å; T191-V193 PolarHBondContact O-N 2.87Å; V193-V195 VanDerWaalsContact C-N 3.33Å; V193-V195 PolarHBondContact O-N 3.39Å; V193-A196 PolarHBondContact O-N 2.73Å; V193-W197 PolarHBondContact O-N 3.05Å
194	I	91.7	Very high	81.9	Confident	105 Å²	105	69.9 Å²	69.9	54%	0.538	39%	0.39	S	S	.	.	H	α-helix	trans	-61.9	-41.7	176.4	-67.1	163.5	0	0	0	110.6	N190 T191 A198	N190-I194 HydrophobicContact CB-CD1 3.92Å; N190-I194 HydrophobicContact CB-CG1 4.46Å; N190-I194 WeakPolarHBondContact O-CG1 3.29Å; N190-I194 PolarHBondContact O-N 3.27Å; T191-I194 PolarHBondContact O-N 2.84Å; I194-A198 WeakPolarHBondContact O-CB 3.14Å; I194-A198 PolarHBondContact O-N 2.69Å
195	V	93.4	Very high	83.9	Confident	75 Å²	75	71 Å²	71	46%	0.455	38%	0.381	S	S	.	.	H	α-helix	trans	-65.3	-43.4	175.9	169.8	0	0	0	0	111.2	T191 V193 A198 L199	T191-V195 HydrophobicContact CG2-CG2 4.24Å; T191-V195 WeakPolarHBondContact O-CB 3.29Å; T191-V195 VanDerWaalsContact O-CG2 3.3Å; T191-V195 WeakPolarHBondContact O-CG2 3.3Å; T191-V195 PolarHBondContact O-N 3.47Å; V193-V195 VanDerWaalsContact C-N 3.33Å; V193-V195 PolarHBondContact O-N 3.39Å; V195-A198 PolarHBondContact O-N 3.35Å; V195-L199 HydrophobicContact CG1-CD1 3.82Å; V195-L199 HydrophobicContact CG1-CG 4.32Å; V195-L199 WeakPolarHBondContact O-CB 3.42Å; V195-L199 VanDerWaalsContact O-CG 3.27Å; V195-L199 WeakPolarHBondContact O-CG 3.41Å; V195-L199 PolarHBondContact O-N 3.07Å
196	A	94.4	Very high	85.7	Confident	3 Å²	3	69.9 Å²	69.9	3%	0.025	37%	0.368	C	S	.	.	H	α-helix	trans	-60.8	-46.6	176.6	0	0	0	0	0	112.5	M162 A165 P192 V193 A200	M162-A196 HydrophobicContact CG-CB 4.48Å; M162-A196 HydrophobicContact SD-CB 4.04Å; A165-A196 HydrophobicContact CB-CB 4.27Å; P192-A196 WeakPolarHBondContact O-CB 3.31Å; P192-A196 PolarHBondContact O-N 3.06Å; V193-A196 PolarHBondContact O-N 2.73Å; A196-A200 WeakPolarHBondContact O-CB 3.37Å; A196-A200 PolarHBondContact O-N 2.94Å
197	W	96.4	Very high	87.6	Confident	56 Å²	56	62.3 Å²	62.3	21%	0.212	33%	0.331	C	S	.	.	H	α-helix	trans	-66.8	-41.1	175.9	-81.9	108.8	0	0	0	112.9	N113 V116 V154 A158 V193 A200 L201	N113-W197 PolarHBondContact OD1-NE1 3.28Å; V116-W197 HydrophobicContact CG1-CH2 4.24Å; V116-W197 HydrophobicContact CG1-CZ2 4.08Å; V154-W197 HydrophobicContact CG1-CZ3 4.26Å; A158-W197 HydrophobicContact CB-CE3 4.1Å; A158-W197 HydrophobicContact CB-CH2 4.07Å; A158-W197 HydrophobicContact CB-CZ3 3.82Å; V193-W197 PolarHBondContact O-N 3.05Å; W197-A200 PolarHBondContact O-N 3.4Å; W197-L201 WeakPolarHBondContact O-CB 3.3Å; W197-L201 VanDerWaalsContact O-CG 3.29Å; W197-L201 WeakPolarHBondContact O-CG 3.47Å; W197-L201 PolarHBondContact O-N 3.35Å
198	A	96.4	Very high	89.4	Confident	47 Å²	47	59.8 Å²	59.8	39%	0.388	31%	0.311	S	S	.	.	H	α-helix	trans	-63.9	-44	177.6	0	0	0	0	0	111.7	I194 V195 L201 V202	I194-A198 WeakPolarHBondContact O-CB 3.14Å; I194-A198 PolarHBondContact O-N 2.69Å; V195-A198 PolarHBondContact O-N 3.35Å; A198-L201 PolarHBondContact O-N 3.34Å; A198-V202 WeakPolarHBondContact O-CB 3.27Å; A198-V202 VanDerWaalsContact O-CG2 3.25Å; A198-V202 WeakPolarHBondContact O-CG2 3.14Å; A198-V202 PolarHBondContact O-N 3.05Å
199	L	95.8	Very high	90.5	Very high	72 Å²	72	58.5 Å²	58.5	38%	0.377	31%	0.311	S	S	.	.	H	α-helix	trans	-59.9	-47.7	172.3	-73.4	170.7	0	0	0	110.9	Y161 V195 L201 V202 L203	Y161-L199 HydrophobicContact CD1-CD1 4.39Å; Y161-L199 HydrophobicContact CD2-CB 4.33Å; Y161-L199 HydrophobicContact CE1-CD1 4.48Å; Y161-L199 HydrophobicContact CE2-CB 4.48Å; V195-L199 HydrophobicContact CG1-CD1 3.82Å; V195-L199 HydrophobicContact CG1-CG 4.32Å; V195-L199 WeakPolarHBondContact O-CB 3.42Å; V195-L199 VanDerWaalsContact O-CG 3.27Å; V195-L199 WeakPolarHBondContact O-CG 3.41Å; V195-L199 PolarHBondContact O-N 3.07Å; L199-L201 PolarHBondContact O-N 3.33Å; L199-V202 PolarHBondContact O-N 2.77Å; L199-L203 HydrophobicContact CB-CD1 4.15Å; L199-L203 HydrophobicContact CD2-CD1 4.49Å; L199-L203 VanDerWaalsContact O-CB 3.26Å; L199-L203 WeakPolarHBondContact O-CB 3.43Å; L199-L203 WeakPolarHBondContact O-CD1 3.38Å; L199-L203 WeakPolarHBondContact O-CG 3.29Å; L199-L203 PolarHBondContact O-N 3.5Å
200	A	96.7	Very high	91.2	Very high	0 Å²	0	53.9 Å²	53.9	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-59.2	-45.7	178.8	0	0	0	0	0	112.8	F157 A158 A196 W197 S204	F157-A200 HydrophobicContact CB-CB 3.64Å; A158-A200 HydrophobicContact CB-CB 4.02Å; A196-A200 WeakPolarHBondContact O-CB 3.37Å; A196-A200 PolarHBondContact O-N 2.94Å; W197-A200 PolarHBondContact O-N 3.4Å; A200-S204 WeakPolarHBondContact O-CB 3.48Å; A200-S204 PolarHBondContact O-N 3.16Å; A200-S204 PolarHBondContact O-OG 3.44Å
201	L	96.1	Very high	91.5	Very high	75 Å²	75	49.5 Å²	49.5	39%	0.393	27%	0.272	S	S	.	.	H	α-helix	trans	-65.1	-41.2	178.5	-70.7	166.7	0	0	0	112.5	Y150 V154 W197 A198 L199	Y150-L201 HydrophobicContact CE1-CD2 4.46Å; Y150-L201 WeakPolarHBondContact OH-CD2 3.44Å; Y150-L201 PolarHBondContact OH-O 3.03Å; V154-L201 HydrophobicContact CG1-CD2 3.9Å; V154-L201 HydrophobicContact CG2-CD2 4.13Å; W197-L201 WeakPolarHBondContact O-CB 3.3Å; W197-L201 VanDerWaalsContact O-CG 3.29Å; W197-L201 WeakPolarHBondContact O-CG 3.47Å; W197-L201 PolarHBondContact O-N 3.35Å; A198-L201 PolarHBondContact O-N 3.34Å; L199-L201 PolarHBondContact O-N 3.33Å
202	V	96.5	Very high	91.5	Very high	90 Å²	90	47.8 Å²	47.8	55%	0.545	26%	0.262	S	S	.	.	H	α-helix	trans	-74.4	-45.4	-178	170.7	0	0	0	0	112.1	A198 L199 S204 I205	A198-V202 WeakPolarHBondContact O-CB 3.27Å; A198-V202 VanDerWaalsContact O-CG2 3.25Å; A198-V202 WeakPolarHBondContact O-CG2 3.14Å; A198-V202 PolarHBondContact O-N 3.05Å; L199-V202 PolarHBondContact O-N 2.77Å; V202-S204 PolarHBondContact O-N 3.37Å; V202-I205 HydrophobicContact CB-CD1 4.44Å; V202-I205 HydrophobicContact CG1-CD1 4.37Å; V202-I205 WeakPolarHBondContact O-CB 3.46Å; V202-I205 VanDerWaalsContact O-CG1 3.3Å; V202-I205 WeakPolarHBondContact O-CG1 3.15Å; V202-I205 PolarHBondContact O-N 2.89Å; V202-I205 VanDerWaalsContact O-N 3.08Å
203	L	94.3	Very high	91.2	Very high	30 Å²	30	49.9 Å²	49.9	16%	0.157	26%	0.264	C	S	.	.	H	α-helix	trans	-68.2	-17.7	179.8	-61.4	167.2	0	0	0	112.3	F157 Y161 L199 W239	F157-L203 HydrophobicContact CD1-CD1 4.44Å; F157-L203 HydrophobicContact CD2-CB 4.1Å; F157-L203 HydrophobicContact CE1-CB 4.22Å; F157-L203 HydrophobicContact CE1-CD1 4.38Å; F157-L203 HydrophobicContact CE2-CB 3.79Å; F157-L203 HydrophobicContact CG-CB 4.45Å; F157-L203 HydrophobicContact CZ-CB 3.86Å; Y161-L203 HydrophobicContact CD2-CD1 4.48Å; Y161-L203 HydrophobicContact CE2-CD1 3.45Å; Y161-L203 VanDerWaalsContact CE2-CD1 3.45Å; Y161-L203 WeakPolarHBondContact OH-CD1 3.36Å; L199-L203 HydrophobicContact CB-CD1 4.15Å; L199-L203 HydrophobicContact CD2-CD1 4.49Å; L199-L203 VanDerWaalsContact O-CB 3.26Å; L199-L203 WeakPolarHBondContact O-CB 3.43Å; L199-L203 WeakPolarHBondContact O-CD1 3.38Å; L199-L203 WeakPolarHBondContact O-CG 3.29Å; L199-L203 PolarHBondContact O-N 3.5Å; L203-W239 HydrophobicContact CB-CZ2 4.47Å; L203-W239 HydrophobicContact CD2-CH2 3.63Å; L203-W239 HydrophobicContact CD2-CZ2 3.52Å
204	S	93.3	Very high	90.6	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	27%	0.268	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.7	-12.4	173	-56.3	0	0	0	0	114.5	Y150 I153 V154 F157 A200 V202 P206 Q207	Y150-S204 VanDerWaalsContact CD2-O 3.32Å; Y150-S204 WeakPolarHBondContact CD2-O 3.41Å; Y150-S204 VanDerWaalsContact CE2-CB 3.41Å; I153-S204 WeakPolarHBondContact CG2-OG 3.44Å; V154-S204 WeakPolarHBondContact CA-OG 3.4Å; V154-S204 VanDerWaalsContact CG2-CB 3.48Å; V154-S204 VanDerWaalsContact CG2-OG 3.27Å; V154-S204 WeakPolarHBondContact CG2-OG 3.21Å; V154-S204 PolarHBondContact N-OG 2.87Å; F157-S204 WeakPolarHBondContact CD2-OG 3.11Å; A200-S204 WeakPolarHBondContact O-CB 3.48Å; A200-S204 PolarHBondContact O-N 3.16Å; A200-S204 PolarHBondContact O-OG 3.44Å; V202-S204 PolarHBondContact O-N 3.37Å; S204-P206 VanDerWaalsContact C-N 3.35Å; S204-Q207 WeakPolarHBondContact O-CB 3.37Å; S204-Q207 WeakPolarHBondContact O-CG 3.26Å; S204-Q207 PolarHBondContact O-N 3.42Å
205	I	92.8	Very high	90	Very high	79 Å²	79	50.9 Å²	50.9	41%	0.405	27%	0.268	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.6	-39.8	-174.7	-71.5	172.5	0	0	0	114.4	V202 Q207 V208 F209	V202-I205 HydrophobicContact CB-CD1 4.44Å; V202-I205 HydrophobicContact CG1-CD1 4.37Å; V202-I205 WeakPolarHBondContact O-CB 3.46Å; V202-I205 VanDerWaalsContact O-CG1 3.3Å; V202-I205 WeakPolarHBondContact O-CG1 3.15Å; V202-I205 PolarHBondContact O-N 2.89Å; V202-I205 VanDerWaalsContact O-N 3.08Å; I205-Q207 PolarHBondContact O-N 2.98Å; I205-V208 PolarHBondContact O-N 3.25Å; I205-F209 HydrophobicContact CG2-CD2 4.38Å; I205-F209 HydrophobicContact CG2-CE2 3.76Å
206	P	89.5	Confident	89.2	Confident	49 Å²	49	51 Å²	51	32%	0.318	27%	0.269	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.7	-27.1	-179.5	-29.5	37.3	0	0	0	115.2	S204 V208 F209 I210	S204-P206 VanDerWaalsContact C-N 3.35Å; P206-V208 VanDerWaalsContact C-N 3.26Å; P206-V208 PolarHBondContact O-N 3.44Å; P206-F209 PolarHBondContact O-N 3.45Å; P206-F209 VanDerWaalsContact O-N 3.12Å; P206-I210 HydrophobicContact CB-CD1 4Å; P206-I210 WeakPolarHBondContact O-CG1 3.45Å; P206-I210 PolarHBondContact O-N 3.21Å
207	Q	86.7	Confident	88.3	Confident	3 Å²	3	53.1 Å²	53.1	1%	0.014	29%	0.286	C	S	.	.	H	α-helix	trans	-58.8	-36.7	-178.3	-58	-57.9	-31.6	0	0	113.3	Y150 I153 S204 I205 F209 F211 Y236	Y150-Q207 HydrophobicContact CD2-CB 4.43Å; I153-Q207 HydrophobicContact CB-CG 3.85Å; I153-Q207 HydrophobicContact CD1-CG 4.49Å; I153-Q207 VanDerWaalsContact CD1-NE2 3.32Å; I153-Q207 VanDerWaalsContact CG1-CD 3.47Å; I153-Q207 HydrophobicContact CG1-CG 3.72Å; I153-Q207 HydrophobicContact CG2-CG 3.99Å; S204-Q207 WeakPolarHBondContact O-CB 3.37Å; S204-Q207 WeakPolarHBondContact O-CG 3.26Å; S204-Q207 PolarHBondContact O-N 3.42Å; I205-Q207 PolarHBondContact O-N 2.98Å; Q207-F209 PolarHBondContact O-N 2.99Å; Q207-F211 PolarHBondContact O-N 2.92Å; Q207-F211 VanDerWaalsContact OE1-CD2 3.28Å; Q207-Y236 VanDerWaalsContact NE2-CE2 3.33Å; Q207-Y236 PolarHBondContact NE2-OH 3.05Å; Q207-Y236 PolarHBondContact OE1-OH 2.94Å
208	V	88.8	Confident	87.1	Confident	53 Å²	53	56.5 Å²	56.5	32%	0.321	32%	0.315	S	S	.	.	H	α-helix	trans	-69	-23	-177	-173.2	0	0	0	0	111.7	R146 Y150 I205 P206	R146-V208 PolarHBondContact NH1-O 2.9Å; Y150-V208 HydrophobicContact CD2-CG2 3.69Å; Y150-V208 HydrophobicContact CE2-CG2 4.38Å; Y150-V208 HydrophobicContact CG-CG2 4.07Å; I205-V208 PolarHBondContact O-N 3.25Å; P206-V208 VanDerWaalsContact C-N 3.26Å; P206-V208 PolarHBondContact O-N 3.44Å
209	F	88.6	Confident	86	Confident	160 Å²	160	56.7 Å²	56.7	70%	0.702	32%	0.323	S	S	*	.	H	α-helix	trans	-97.8	-34.8	179.4	-59.1	-72.9	0	0	0	113.1	I205 P206 Q207	I205-F209 HydrophobicContact CG2-CD2 4.38Å; I205-F209 HydrophobicContact CG2-CE2 3.76Å; P206-F209 PolarHBondContact O-N 3.45Å; P206-F209 VanDerWaalsContact O-N 3.12Å; Q207-F209 PolarHBondContact O-N 2.99Å
210	I	82.8	Confident	85.1	Confident	29 Å²	29	56.8 Å²	56.8	15%	0.149	32%	0.321	C	S	.	.	H	α-helix	trans	-75.4	-46	-179.9	-66	166.5	0	0	0	111.3	P206 H226 F227 Y236	P206-I210 HydrophobicContact CB-CD1 4Å; P206-I210 WeakPolarHBondContact O-CG1 3.45Å; P206-I210 PolarHBondContact O-N 3.21Å; I210-H226 PolarHBondContact O-N 2.87Å; I210-F227 HydrophobicContact CD1-CE1 4.49Å; I210-F227 HydrophobicContact CG2-CD1 4.11Å; I210-F227 HydrophobicContact CG2-CE1 3.54Å; I210-F227 HydrophobicContact CG2-CE2 4.36Å; I210-F227 HydrophobicContact CG2-CZ 3.69Å; I210-Y236 HydrophobicContact CD1-CD2 3.85Å; I210-Y236 HydrophobicContact CD1-CE2 4.16Å; I210-Y236 HydrophobicContact CD1-CG 4.43Å
211	F	84.8	Confident	84.2	Confident	2 Å²	2	60.1 Å²	60.1	1%	0.009	34%	0.335	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.9	137.6	-174.1	-68.4	-84.6	0	0	0	112.4	R146 K149 Q207 W224 F227	R146-F211 WeakPolarHBondContact CG-O 3.26Å; K149-F211 HydrophobicContact CB-CB 4.03Å; K149-F211 HydrophobicContact CB-CD2 4.13Å; K149-F211 HydrophobicContact CB-CG 4.08Å; K149-F211 HydrophobicContact CD-CD1 4.1Å; K149-F211 HydrophobicContact CD-CD2 4.43Å; K149-F211 HydrophobicContact CD-CE1 4.32Å; K149-F211 HydrophobicContact CD-CG 4.16Å; K149-F211 HydrophobicContact CG-CB 3.85Å; K149-F211 HydrophobicContact CG-CD1 4.07Å; K149-F211 HydrophobicContact CG-CD2 4.23Å; K149-F211 HydrophobicContact CG-CG 3.78Å; Q207-F211 PolarHBondContact O-N 2.92Å; Q207-F211 VanDerWaalsContact OE1-CD2 3.28Å; F211-W224 WeakPolarHBondContact CA-O 3.41Å; F211-F227 HydrophobicContact CZ-CZ 4.26Å
212	S	84.4	Confident	83.2	Confident	20 Å²	20	60 Å²	60	14%	0.14	33%	0.333	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-155.9	165.9	172.4	62.7	0	0	0	0	110.8	D142 S214 C223 W224 H226	D142-S212 WeakPolarHBondContact OD1-CA 3.35Å; D142-S212 WeakPolarHBondContact OD1-CB 3.08Å; S212-S214 PolarHBondContact O-N 3.08Å; S212-C223 CarbonylContact O-C 3.41Å; S212-W224 PolarHBondContact N-O 2.99Å; S212-W224 VanDerWaalsContact N-O 3.11Å; S212-W224 PolarHBondContact O-N 3.21Å; S212-H226 PolarHBondContact OG-CE1 3.03Å; S212-H226 VanDerWaalsContact OG-CE1 3.25Å; S212-H226 PolarHBondContact OG-ND1 3.47Å
213	R	82.1	Confident	82.5	Confident	90 Å²	90	56.4 Å²	56.4	34%	0.34	31%	0.312	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-67.9	129.4	167.1	177.6	172	164	160.5	-3.9	109.6	G140 D142 F221 E222	G140-R213 PolarHBondContact O-NH1 3.03Å; D142-R213 HydrophobicContact CB-CB 4.03Å; D142-R213 PolarHBondContact OD1-N 2.93Å; R213-F221 HydrophobicContact CG-CB 4.31Å; R213-F221 HydrophobicContact CG-CD1 4.24Å; R213-E222 CarbonylContact C-O 3.57Å; R213-E222 VanDerWaalsContact CA-O 3.24Å; R213-E222 WeakPolarHBondContact CA-O 3.37Å
214	S	76.4	Confident	81.7	Confident	21 Å²	21	59.3 Å²	59.3	15%	0.147	32%	0.321	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-130.5	163.3	172.4	62.9	0	0	0	0	110.6	S212 F221 E222 W224	S212-S214 PolarHBondContact O-N 3.08Å; S214-F221 VanDerWaalsContact O-CA 3.28Å; S214-F221 WeakPolarHBondContact O-CA 3.47Å; S214-E222 PolarHBondContact N-O 3.37Å; S214-E222 PolarHBondContact O-N 3.41Å; S214-W224 WeakPolarHBondContact OG-CB 3.23Å
215	E	80.8	Confident	81	Confident	114 Å²	114	59.8 Å²	59.8	53%	0.533	33%	0.325	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.7	124.6	166.7	-170.9	168.7	-175	0	0	107.6	A217 P218 G219 E220 F221	E215-A217 VanDerWaalsContact CG-O 3.28Å; E215-A217 WeakPolarHBondContact CG-O 3.43Å; E215-P218 WeakPolarHBondContact OE1-CA 3.39Å; E215-G219 PolarHBondContact OE1-N 2.82Å; E215-E220 WeakPolarHBondContact CA-O 3.48Å; E215-F221 HydrophobicContact CB-CD1 4.07Å; E215-F221 HydrophobicContact CB-CE1 3.88Å; E215-F221 HydrophobicContact CG-CE1 4.28Å; E215-F221 HydrophobicContact CG-CZ 4.5Å
216	V	75.9	Confident	80.1	Confident	77 Å²	77	60.8 Å²	60.8	47%	0.467	33%	0.328	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-104.2	-32.6	-175.7	-179.5	0	0	0	0	111	E220 E222 W224	V216-E220 PolarHBondContact N-O 3.43Å; V216-E222 HydrophobicContact CG2-CB 3.9Å; V216-E222 HydrophobicContact CG2-CG 4.08Å; V216-W224 HydrophobicContact CG2-CE3 4.3Å
217	A	74.4	Confident	79.7	Confident	48 Å²	48	60.2 Å²	60.2	40%	0.397	32%	0.32	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-140	163.2	166.8	0	0	0	0	0	108.6	E215 G219 E220	E215-A217 VanDerWaalsContact CG-O 3.28Å; E215-A217 WeakPolarHBondContact CG-O 3.43Å; A217-G219 PolarHBondContact O-N 3.37Å; A217-E220 HydrophobicContact CB-CB 4.21Å; A217-E220 HydrophobicContact CB-CG 4.49Å; A217-E220 PolarHBondContact O-N 3.28Å
218	P	71	Confident	79.3	Confident	127 Å²	127	64.3 Å²	64.3	83%	0.825	35%	0.346	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.3	112.5	-173.8	-27.9	36.5	0	0	0	113.4	E215 E220	E215-P218 WeakPolarHBondContact OE1-CA 3.39Å; P218-E220 VanDerWaalsContact C-N 3.34Å
219	G	74.7	Confident	78.8	Confident	52 Å²	52	70.1 Å²	70.1	54%	0.536	37%	0.369	S	S	.	.	T	Hydrogen-bonded Turn	trans	82.7	-6.7	-175.7	0	0	0	0	0	116.4	E215 A217 F221	E215-G219 PolarHBondContact OE1-N 2.82Å; A217-G219 PolarHBondContact O-N 3.37Å; G219-F221 WeakPolarHBondContact O-CD2 3.11Å
220	E	75.9	Confident	78.3	Confident	74 Å²	74	68.1 Å²	68.1	35%	0.346	37%	0.373	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.8	120	-179	-67.5	-75.7	-164.7	0	0	110.9	R137 E215 V216 A217 P218	R137-E220 WeakPolarHBondContact CD-OE2 3.43Å; R137-E220 IonicContact CZ-OE1 3.34Å; R137-E220 IonicContact CZ-OE2 3.77Å; R137-E220 IonicContact NE-OE1 3.14Å; R137-E220 PolarHBondContact NE-OE1 3.4Å; R137-E220 VanDerWaalsContact NE-OE1 3.14Å; R137-E220 IonicContact NE-OE2 2.82Å; R137-E220 PolarHBondContact NE-OE2 3.12Å; R137-E220 IonicContact NH2-OE1 2.69Å; R137-E220 PolarHBondContact NH2-OE1 3.1Å; R137-E220 IonicContact NH2-OE2 3.86Å; E215-E220 WeakPolarHBondContact CA-O 3.48Å; V216-E220 PolarHBondContact N-O 3.43Å; A217-E220 HydrophobicContact CB-CB 4.21Å; A217-E220 HydrophobicContact CB-CG 4.49Å; A217-E220 PolarHBondContact O-N 3.28Å; P218-E220 VanDerWaalsContact C-N 3.34Å
221	F	77.5	Confident	78.2	Confident	69 Å²	69	74.1 Å²	74.1	30%	0.303	39%	0.394	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.5	133.2	-173.1	-65.8	-88.6	0	0	0	113	R213 S214 E215 G219	R213-F221 HydrophobicContact CG-CB 4.31Å; R213-F221 HydrophobicContact CG-CD1 4.24Å; S214-F221 VanDerWaalsContact O-CA 3.28Å; S214-F221 WeakPolarHBondContact O-CA 3.47Å; E215-F221 HydrophobicContact CB-CD1 4.07Å; E215-F221 HydrophobicContact CB-CE1 3.88Å; E215-F221 HydrophobicContact CG-CE1 4.28Å; E215-F221 HydrophobicContact CG-CZ 4.5Å; G219-F221 WeakPolarHBondContact O-CD2 3.11Å
222	E	76.3	Confident	77.9	Confident	73 Å²	73	74.5 Å²	74.5	34%	0.341	40%	0.398	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-130.8	173.6	176.9	-61.7	-158.6	167	0	0	112.7	R213 S214 V216	R213-E222 CarbonylContact C-O 3.57Å; R213-E222 VanDerWaalsContact CA-O 3.24Å; R213-E222 WeakPolarHBondContact CA-O 3.37Å; S214-E222 PolarHBondContact N-O 3.37Å; S214-E222 PolarHBondContact O-N 3.41Å; V216-E222 HydrophobicContact CG2-CB 3.9Å; V216-E222 HydrophobicContact CG2-CG 4.08Å
223	C	80.9	Confident	77.6	Confident	14 Å²	14	74.8 Å²	74.8	10%	0.095	40%	0.398	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.5	84.3	176.1	-178.6	0	0	0	0	109.3	W132 F138 C145 S212	W132-C223 HydrophobicContact CH2-CB 4.02Å; W132-C223 HydrophobicContact CZ2-CB 3.63Å; F138-C223 HydrophobicContact CD1-CB 4.25Å; F138-C223 HydrophobicContact CE1-CB 4.47Å; F138-C223 HydrophobicContact CG-CB 4.39Å; C145-C223 VanDerWaalsContact CA-SG 3.53Å; C145-C223 HydrophobicContact CB-CB 3.77Å; C145-C223 WeakPolarHBondContact CB-SG 3.12Å; C145-C223 WeakPolarHBondContact SG-CA 3.18Å; C145-C223 WeakPolarHBondContact SG-CB 3.43Å; C145-C223 CovalentContact SG-SG 2.03Å; C145-C223 PolarHBondContact SG-SG 3.31Å; S212-C223 CarbonylContact O-C 3.41Å
224	W	77.8	Confident	77.6	Confident	92 Å²	92	74 Å²	74	35%	0.348	40%	0.397	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.1	152.7	-166.2	-166.4	-97.1	0	0	0	113.4	F211 S212 S214 V216	F211-W224 WeakPolarHBondContact CA-O 3.41Å; S212-W224 PolarHBondContact N-O 2.99Å; S212-W224 VanDerWaalsContact N-O 3.11Å; S212-W224 PolarHBondContact O-N 3.21Å; S214-W224 WeakPolarHBondContact OG-CB 3.23Å; V216-W224 HydrophobicContact CG2-CE3 4.3Å
225	G	78.1	Confident	78.1	Confident	9 Å²	9	75.2 Å²	75.2	9%	0.093	41%	0.408	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.6	117.6	177.2	0	0	0	0	0	112.2	F227	G225-F227 WeakPolarHBondContact O-CD2 3.23Å; G225-F227 PolarHBondContact O-N 2.85Å
226	H	75.1	Confident	78.3	Confident	100 Å²	100	70.3 Å²	70.3	46%	0.463	38%	0.384	S	S	.	.			trans	-92.8	95.8	179.7	-61.7	77.7	0	0	0	109.6	I210 S212	I210-H226 PolarHBondContact O-N 2.87Å; S212-H226 PolarHBondContact OG-CE1 3.03Å; S212-H226 VanDerWaalsContact OG-CE1 3.25Å; S212-H226 PolarHBondContact OG-ND1 3.47Å
227	F	80.2	Confident	78.7	Confident	37 Å²	37	66.8 Å²	66.8	16%	0.162	36%	0.363	C	S	.	.			trans	-99.6	138.5	-178.8	-61.9	-79.1	0	0	0	111.7	I50 I210 F211 G225 E229 L233 Y236	I50-F227 HydrophobicContact CD1-CD2 4.02Å; I210-F227 HydrophobicContact CD1-CE1 4.49Å; I210-F227 HydrophobicContact CG2-CD1 4.11Å; I210-F227 HydrophobicContact CG2-CE1 3.54Å; I210-F227 HydrophobicContact CG2-CE2 4.36Å; I210-F227 HydrophobicContact CG2-CZ 3.69Å; F211-F227 HydrophobicContact CZ-CZ 4.26Å; G225-F227 WeakPolarHBondContact O-CD2 3.23Å; G225-F227 PolarHBondContact O-N 2.85Å; F227-E229 PolarHBondContact O-N 3.26Å; F227-L233 HydrophobicContact CD2-CD1 4.22Å; F227-L233 HydrophobicContact CE1-CD1 4.24Å; F227-L233 HydrophobicContact CE2-CD1 3.9Å; F227-L233 HydrophobicContact CG-CB 4.41Å; F227-L233 HydrophobicContact CZ-CD1 3.92Å; F227-Y236 AromaticContact CE1-CD1 3.51Å; F227-Y236 HydrophobicContact CE1-CD1 3.51Å; F227-Y236 HydrophobicContact CE1-CE1 4.23Å; F227-Y236 AromaticContact CE1-CG 3.75Å; F227-Y236 HydrophobicContact CE1-CG 3.75Å; F227-Y236 AromaticContact CZ-CD1 3.83Å; F227-Y236 HydrophobicContact CZ-CD1 3.83Å; F227-Y236 HydrophobicContact CZ-CE1 4.19Å; F227-Y236 HydrophobicContact CZ-CG 4.49Å
228	T	78.6	Confident	79.4	Confident	90 Å²	90	66.7 Å²	66.7	55%	0.552	36%	0.358	S	S	*	.			trans	-71.4	110.1	173.4	-49.1	0	0	0	0	110.5	W231 G232	T228-W231 HydrophobicContact CG2-CZ2 4.13Å; T228-W231 PolarHBondContact O-N 3.07Å; T228-G232 VanDerWaalsContact O-CA 3.3Å; T228-G232 WeakPolarHBondContact O-CA 3.49Å; T228-G232 PolarHBondContact O-N 2.89Å
229	E	78.7	Confident	80.3	Confident	174 Å²	174	65.7 Å²	65.7	81%	0.813	34%	0.337	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.2	152.3	175.7	-65.1	-172.2	167.9	0	0	112.4	F227	F227-E229 PolarHBondContact O-N 3.26Å
230	P	78.1	Confident	80.9	Confident	118 Å²	118	63.6 Å²	63.6	77%	0.766	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	cis	-88.9	0.5	-8.7	35.8	-37.7	0	0	0	113.9
231	W	80.9	Confident	81.6	Confident	156 Å²	156	60.5 Å²	60.5	59%	0.591	30%	0.3	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106.5	-16.4	-164.8	59	-95.2	0	0	0	115.1	T228 L233 K234 A235	T228-W231 HydrophobicContact CG2-CZ2 4.13Å; T228-W231 PolarHBondContact O-N 3.07Å; W231-L233 PolarHBondContact O-N 3.43Å; W231-K234 PolarHBondContact O-N 3.11Å; W231-K234 VanDerWaalsContact O-N 3.16Å; W231-A235 HydrophobicContact CE3-CB 3.8Å; W231-A235 HydrophobicContact CZ3-CB 4.13Å; W231-A235 WeakPolarHBondContact O-CB 3.33Å; W231-A235 PolarHBondContact O-N 2.81Å
232	G	78.8	Confident	82.3	Confident	9 Å²	9	60.3 Å²	60.3	9%	0.093	30%	0.304	C	S	.	.	H	α-helix	trans	-59	-47.2	-169.5	0	0	0	0	0	114.2	T228 Y236	T228-G232 VanDerWaalsContact O-CA 3.3Å; T228-G232 WeakPolarHBondContact O-CA 3.49Å; T228-G232 PolarHBondContact O-N 2.89Å; G232-Y236 VanDerWaalsContact O-CB 3.23Å; G232-Y236 WeakPolarHBondContact O-CB 3.43Å; G232-Y236 PolarHBondContact O-N 3.08Å
233	L	78.3	Confident	83.1	Confident	27 Å²	27	57 Å²	57	14%	0.141	29%	0.289	C	S	.	.	H	α-helix	trans	-62.3	-45.3	175.9	-175	73.7	0	0	0	111.2	I48 I50 F227 W231 A235 Y236 V237	I48-L233 HydrophobicContact CG2-CD1 4.32Å; I50-L233 HydrophobicContact CD1-CB 4.16Å; I50-L233 HydrophobicContact CD1-CD1 4.17Å; I50-L233 HydrophobicContact CD1-CD2 3.85Å; I50-L233 HydrophobicContact CD1-CG 4.27Å; I50-L233 HydrophobicContact CG1-CD1 4.35Å; I50-L233 HydrophobicContact CG1-CD2 4.02Å; F227-L233 HydrophobicContact CD2-CD1 4.22Å; F227-L233 HydrophobicContact CE1-CD1 4.24Å; F227-L233 HydrophobicContact CE2-CD1 3.9Å; F227-L233 HydrophobicContact CG-CB 4.41Å; F227-L233 HydrophobicContact CZ-CD1 3.92Å; W231-L233 PolarHBondContact O-N 3.43Å; L233-A235 PolarHBondContact O-N 3.42Å; L233-Y236 PolarHBondContact O-N 2.96Å; L233-V237 HydrophobicContact CD1-CG2 4.23Å; L233-V237 HydrophobicContact CG-CG2 4.33Å; L233-V237 WeakPolarHBondContact O-CG2 3.35Å; L233-V237 PolarHBondContact O-N 2.89Å
234	K	81.1	Confident	83.6	Confident	74 Å²	74	56.3 Å²	56.3	32%	0.322	28%	0.284	S	S	.	.	H	α-helix	trans	-62.6	-46.3	-177.8	-51.6	-152.6	177.7	-164.2	0	110.9	W231 T238 A423 W424	W231-K234 PolarHBondContact O-N 3.11Å; W231-K234 VanDerWaalsContact O-N 3.16Å; K234-T238 VanDerWaalsContact O-CB 3.27Å; K234-T238 WeakPolarHBondContact O-CB 3.42Å; K234-T238 PolarHBondContact O-N 3.31Å; K234-T238 PolarHBondContact O-OG1 3.48Å; K234-T238 VanDerWaalsContact O-OG1 3.05Å; K234-A423 WeakPolarHBondContact CD-O 3.3Å; K234-A423 WeakPolarHBondContact CE-O 3.42Å; K234-A423 WeakPolarHBondContact CG-O 3.28Å; K234-W424 HydrophobicContact CB-CZ2 4.15Å; K234-W424 HydrophobicContact CD-CD2 4.11Å; K234-W424 HydrophobicContact CD-CE3 4.23Å; K234-W424 HydrophobicContact CD-CG 4.49Å; K234-W424 PolarHBondContact NZ-O 3.42Å; K234-W424 VanDerWaalsContact NZ-O 3.07Å
235	A	87.4	Confident	84.2	Confident	45 Å²	45	52.9 Å²	52.9	37%	0.372	27%	0.272	S	S	.	.	H	α-helix	trans	-62.6	-43.3	175	0	0	0	0	0	112.1	W231 L233 W239	W231-A235 HydrophobicContact CE3-CB 3.8Å; W231-A235 HydrophobicContact CZ3-CB 4.13Å; W231-A235 WeakPolarHBondContact O-CB 3.33Å; W231-A235 PolarHBondContact O-N 2.81Å; L233-A235 PolarHBondContact O-N 3.42Å; A235-W239 WeakPolarHBondContact O-CB 3.07Å; A235-W239 PolarHBondContact O-N 3.27Å
236	Y	84.4	Confident	85	Confident	12 Å²	12	56.6 Å²	56.6	5%	0.047	29%	0.289	C	S	.	.	H	α-helix	trans	-63	-49.8	178.6	173.2	-115.6	0	0	0	112.6	I48 Q207 I210 F227 G232 L233 W239 M240	I48-Y236 HydrophobicContact CD1-CD1 4.44Å; I48-Y236 HydrophobicContact CD1-CE1 3.64Å; I48-Y236 HydrophobicContact CG1-CE1 3.87Å; Q207-Y236 VanDerWaalsContact NE2-CE2 3.33Å; Q207-Y236 PolarHBondContact NE2-OH 3.05Å; Q207-Y236 PolarHBondContact OE1-OH 2.94Å; I210-Y236 HydrophobicContact CD1-CD2 3.85Å; I210-Y236 HydrophobicContact CD1-CE2 4.16Å; I210-Y236 HydrophobicContact CD1-CG 4.43Å; F227-Y236 AromaticContact CE1-CD1 3.51Å; F227-Y236 HydrophobicContact CE1-CD1 3.51Å; F227-Y236 HydrophobicContact CE1-CE1 4.23Å; F227-Y236 AromaticContact CE1-CG 3.75Å; F227-Y236 HydrophobicContact CE1-CG 3.75Å; F227-Y236 AromaticContact CZ-CD1 3.83Å; F227-Y236 HydrophobicContact CZ-CD1 3.83Å; F227-Y236 HydrophobicContact CZ-CE1 4.19Å; F227-Y236 HydrophobicContact CZ-CG 4.49Å; G232-Y236 VanDerWaalsContact O-CB 3.23Å; G232-Y236 WeakPolarHBondContact O-CB 3.43Å; G232-Y236 PolarHBondContact O-N 3.08Å; L233-Y236 PolarHBondContact O-N 2.96Å; Y236-W239 WeakPolarHBondContact O-CB 3.32Å; Y236-W239 PolarHBondContact O-N 2.98Å; Y236-M240 HydrophobicContact CD2-CG 4.15Å; Y236-M240 HydrophobicContact CE1-CG 4.45Å; Y236-M240 HydrophobicContact CE2-CG 3.64Å; Y236-M240 HydrophobicContact CE2-SD 4.05Å; Y236-M240 WeakPolarHBondContact O-CG 3.46Å; Y236-M240 PolarHBondContact O-N 2.84Å
237	V	84.1	Confident	85.9	Confident	3 Å²	3	55.3 Å²	55.3	2%	0.018	29%	0.286	C	S	.	.	H	α-helix	trans	-66.9	-43.8	-180	174.5	0	0	0	0	111	I48 L233 W239 M240 T241 Q419 A423	I48-V237 HydrophobicContact CD1-CG2 4.46Å; I48-V237 HydrophobicContact CG2-CG2 3.63Å; L233-V237 HydrophobicContact CD1-CG2 4.23Å; L233-V237 HydrophobicContact CG-CG2 4.33Å; L233-V237 WeakPolarHBondContact O-CG2 3.35Å; L233-V237 PolarHBondContact O-N 2.89Å; V237-W239 VanDerWaalsContact C-N 3.34Å; V237-W239 PolarHBondContact O-N 2.82Å; V237-M240 PolarHBondContact O-N 2.88Å; V237-T241 PolarHBondContact O-N 3.1Å; V237-T241 PolarHBondContact O-OG1 2.92Å; V237-Q419 HydrophobicContact CG1-CB 4.23Å; V237-Q419 WeakPolarHBondContact CG1-O 3.23Å; V237-A423 HydrophobicContact CB-CB 3.81Å; V237-A423 HydrophobicContact CG1-CB 3.86Å; V237-A423 HydrophobicContact CG2-CB 3.9Å
238	T	88.9	Confident	86.6	Confident	46 Å²	46	53.6 Å²	53.6	28%	0.282	28%	0.278	S	S	.	.	H	α-helix	trans	-61.5	-41.1	174.8	-64.7	0	0	0	0	111.8	K234 T241 V242 L420 W424	K234-T238 VanDerWaalsContact O-CB 3.27Å; K234-T238 WeakPolarHBondContact O-CB 3.42Å; K234-T238 PolarHBondContact O-N 3.31Å; K234-T238 PolarHBondContact O-OG1 3.48Å; K234-T238 VanDerWaalsContact O-OG1 3.05Å; T238-T241 PolarHBondContact O-N 3.4Å; T238-V242 HydrophobicContact CG2-CG2 4.44Å; T238-V242 WeakPolarHBondContact O-CB 3.14Å; T238-V242 VanDerWaalsContact O-CG2 3.28Å; T238-V242 WeakPolarHBondContact O-CG2 3.38Å; T238-V242 PolarHBondContact O-N 3.45Å; T238-L420 WeakPolarHBondContact OG1-CD1 3.4Å; T238-W424 PolarHBondContact OG1-NE1 2.86Å; T238-W424 VanDerWaalsContact OG1-NE1 3.08Å
239	W	90.6	Very high	87.3	Confident	105 Å²	105	50 Å²	50	40%	0.398	26%	0.258	S	S	.	.	H	α-helix	trans	-58.7	-48.6	172.9	165.8	-105.8	0	0	0	112	L203 A235 Y236 V237 V242 A243	L203-W239 HydrophobicContact CB-CZ2 4.47Å; L203-W239 HydrophobicContact CD2-CH2 3.63Å; L203-W239 HydrophobicContact CD2-CZ2 3.52Å; A235-W239 WeakPolarHBondContact O-CB 3.07Å; A235-W239 PolarHBondContact O-N 3.27Å; Y236-W239 WeakPolarHBondContact O-CB 3.32Å; Y236-W239 PolarHBondContact O-N 2.98Å; V237-W239 VanDerWaalsContact C-N 3.34Å; V237-W239 PolarHBondContact O-N 2.82Å; W239-V242 PolarHBondContact O-N 3Å; W239-A243 HydrophobicContact CD2-CB 4.34Å; W239-A243 HydrophobicContact CE3-CB 4.5Å; W239-A243 HydrophobicContact CH2-CB 4.41Å; W239-A243 HydrophobicContact CZ2-CB 4.23Å; W239-A243 VanDerWaalsContact O-CB 3.29Å; W239-A243 WeakPolarHBondContact O-CB 3.34Å; W239-A243 PolarHBondContact O-N 3.38Å
240	M	87	Confident	88.1	Confident	9 Å²	9	46.7 Å²	46.7	4%	0.044	25%	0.245	C	C	.	.	H	α-helix	trans	-61.4	-45.3	178.5	-72	-57.3	-57.1	0	0	111.9	I153 F157 Y236 V237 V242 A243 V244 F416	I153-M240 HydrophobicContact CD1-CE 3.35Å; I153-M240 HydrophobicContact CD1-SD 4.03Å; I153-M240 HydrophobicContact CG2-CE 4.19Å; F157-M240 HydrophobicContact CE2-CE 4.23Å; F157-M240 HydrophobicContact CE2-SD 4.26Å; F157-M240 HydrophobicContact CZ-CE 4.11Å; F157-M240 HydrophobicContact CZ-SD 4.03Å; Y236-M240 HydrophobicContact CD2-CG 4.15Å; Y236-M240 HydrophobicContact CE1-CG 4.45Å; Y236-M240 HydrophobicContact CE2-CG 3.64Å; Y236-M240 HydrophobicContact CE2-SD 4.05Å; Y236-M240 WeakPolarHBondContact O-CG 3.46Å; Y236-M240 PolarHBondContact O-N 2.84Å; V237-M240 PolarHBondContact O-N 2.88Å; M240-V242 PolarHBondContact O-N 2.95Å; M240-A243 PolarHBondContact O-N 3.3Å; M240-V244 HydrophobicContact CE-CG2 3.47Å; M240-V244 VanDerWaalsContact CE-CG2 3.47Å; M240-V244 VanDerWaalsContact O-CB 3.29Å; M240-V244 WeakPolarHBondContact O-CB 3.33Å; M240-V244 PolarHBondContact O-N 3.28Å; M240-F416 HydrophobicContact CB-CE1 4.34Å
241	T	90.1	Very high	88.8	Confident	8 Å²	8	43.7 Å²	43.7	5%	0.049	22%	0.222	C	C	.	.	I	π-helix	trans	-59.6	-43.2	174.6	-63.2	0	0	0	0	112.3	V237 T238 F245 L246 F416	V237-T241 PolarHBondContact O-N 3.1Å; V237-T241 PolarHBondContact O-OG1 2.92Å; T238-T241 PolarHBondContact O-N 3.4Å; T241-F245 WeakPolarHBondContact O-CB 3.42Å; T241-F245 PolarHBondContact O-N 3.43Å; T241-L246 HydrophobicContact CG2-CD1 4.03Å; T241-L246 HydrophobicContact CG2-CG 4.15Å; T241-L246 PolarHBondContact O-N 3.32Å; T241-F416 HydrophobicContact CG2-CB 4.1Å; T241-F416 HydrophobicContact CG2-CD1 4.38Å; T241-F416 HydrophobicContact CG2-CG 4.42Å; T241-F416 VanDerWaalsContact OG1-CD1 3.23Å; T241-F416 WeakPolarHBondContact OG1-CD1 3.37Å
242	V	94	Very high	89.4	Confident	65 Å²	65	36.3 Å²	36.3	39%	0.394	19%	0.194	S	C	.	.	I	π-helix	trans	-66.8	-51.1	178.1	169.3	0	0	0	0	111.3	T238 W239 M240 L246 L247	T238-V242 HydrophobicContact CG2-CG2 4.44Å; T238-V242 WeakPolarHBondContact O-CB 3.14Å; T238-V242 VanDerWaalsContact O-CG2 3.28Å; T238-V242 WeakPolarHBondContact O-CG2 3.38Å; T238-V242 PolarHBondContact O-N 3.45Å; W239-V242 PolarHBondContact O-N 3Å; M240-V242 PolarHBondContact O-N 2.95Å; V242-L246 HydrophobicContact CG2-CD1 4.17Å; V242-L246 PolarHBondContact O-N 2.86Å; V242-L247 VanDerWaalsContact O-CB 3.25Å; V242-L247 WeakPolarHBondContact O-CB 3.15Å; V242-L247 PolarHBondContact O-N 3.31Å
243	A	92.8	Very high	89.9	Confident	3 Å²	3	38.7 Å²	38.7	3%	0.025	21%	0.207	C	C	.	.	I	π-helix	trans	-81	-34.6	-169.3	0	0	0	0	0	113.7	F157 Y161 W239 M240 P248	F157-A243 HydrophobicContact CE1-CB 3.66Å; F157-A243 HydrophobicContact CZ-CB 4.02Å; Y161-A243 PolarHBondContact OH-O 3.25Å; Y161-A243 VanDerWaalsContact OH-O 3.04Å; W239-A243 HydrophobicContact CD2-CB 4.34Å; W239-A243 HydrophobicContact CE3-CB 4.5Å; W239-A243 HydrophobicContact CH2-CB 4.41Å; W239-A243 HydrophobicContact CZ2-CB 4.23Å; W239-A243 VanDerWaalsContact O-CB 3.29Å; W239-A243 WeakPolarHBondContact O-CB 3.34Å; W239-A243 PolarHBondContact O-N 3.38Å; M240-A243 PolarHBondContact O-N 3.3Å; A243-P248 WeakPolarHBondContact O-CD 3.4Å
244	V	89.9	Confident	90.6	Very high	0 Å²	0	41.6 Å²	41.6	0%	0	22%	0.222	C	C	.	.	I	π-helix	trans	-84.1	-41.6	177	178.3	0	0	0	0	111.3	M156 F157 M240 P248 Y408 F416	M156-V244 HydrophobicContact CG-CG1 3.67Å; M156-V244 HydrophobicContact CG-CG2 4.22Å; M156-V244 HydrophobicContact SD-CG1 4.15Å; F157-V244 HydrophobicContact CD1-CG2 3.66Å; F157-V244 HydrophobicContact CE1-CB 4.3Å; F157-V244 HydrophobicContact CE1-CG2 3.33Å; F157-V244 HydrophobicContact CE2-CG2 4.46Å; F157-V244 HydrophobicContact CG-CG2 4.37Å; F157-V244 HydrophobicContact CZ-CG2 3.78Å; M240-V244 HydrophobicContact CE-CG2 3.47Å; M240-V244 VanDerWaalsContact CE-CG2 3.47Å; M240-V244 VanDerWaalsContact O-CB 3.29Å; M240-V244 WeakPolarHBondContact O-CB 3.33Å; M240-V244 PolarHBondContact O-N 3.28Å; V244-P248 VanDerWaalsContact O-CG 3.3Å; V244-P248 WeakPolarHBondContact O-CG 3.05Å; V244-Y408 PolarHBondContact O-OH 3.45Å; V244-F416 HydrophobicContact CB-CE1 4.5Å; V244-F416 HydrophobicContact CB-CE2 3.98Å; V244-F416 HydrophobicContact CB-CZ 3.56Å; V244-F416 HydrophobicContact CG1-CE2 3.69Å; V244-F416 HydrophobicContact CG1-CZ 3.62Å; V244-F416 HydrophobicContact CG2-CZ 4.23Å
245	F	91.4	Very high	91.1	Very high	20 Å²	20	38.5 Å²	38.5	9%	0.088	21%	0.209	C	C	.	.	I	π-helix	trans	-109.2	-63.3	-169.6	173	-121.6	0	0	0	114	T241 L247 A249 Y408 W412 F416	T241-F245 WeakPolarHBondContact O-CB 3.42Å; T241-F245 PolarHBondContact O-N 3.43Å; F245-L247 PolarHBondContact O-N 2.87Å; F245-A249 HydrophobicContact CD2-CB 4.47Å; F245-A249 HydrophobicContact CE2-CB 4.36Å; F245-A249 WeakPolarHBondContact O-CB 3.28Å; F245-A249 PolarHBondContact O-N 3.23Å; F245-Y408 HydrophobicContact CD2-CE1 4.09Å; F245-W412 HydrophobicContact CD2-CB 3.57Å; F245-W412 HydrophobicContact CE2-CB 3.99Å; F245-W412 HydrophobicContact CG-CB 4.31Å; F245-F416 HydrophobicContact CB-CD2 3.37Å; F245-F416 HydrophobicContact CB-CE2 3.63Å; F245-F416 HydrophobicContact CB-CG 4.07Å; F245-F416 HydrophobicContact CD1-CB 4.21Å; F245-F416 HydrophobicContact CD1-CD2 4.31Å; F245-F416 AromaticContact CG-CD2 3.9Å; F245-F416 HydrophobicContact CG-CD2 3.9Å
246	L	94.4	Very high	91.2	Very high	87 Å²	87	37 Å²	37	46%	0.455	20%	0.195	S	C	.	.	I	π-helix	trans	-64.9	-44.2	-168.5	-61.1	175.1	0	0	0	112.9	T241 V242 L250	T241-L246 HydrophobicContact CG2-CD1 4.03Å; T241-L246 HydrophobicContact CG2-CG 4.15Å; T241-L246 PolarHBondContact O-N 3.32Å; V242-L246 HydrophobicContact CG2-CD1 4.17Å; V242-L246 PolarHBondContact O-N 2.86Å; L246-L250 VanDerWaalsContact O-CB 3.25Å; L246-L250 WeakPolarHBondContact O-CB 3.25Å; L246-L250 PolarHBondContact O-N 3.26Å
247	L	95.1	Very high	91.4	Very high	74 Å²	74	40.4 Å²	40.4	39%	0.387	21%	0.213	S	C	.	.	H	α-helix	trans	-66.6	-50.9	179.7	172.9	65.8	0	0	0	111.8	V242 F245 A249 L250 I251	V242-L247 VanDerWaalsContact O-CB 3.25Å; V242-L247 WeakPolarHBondContact O-CB 3.15Å; V242-L247 PolarHBondContact O-N 3.31Å; F245-L247 PolarHBondContact O-N 2.87Å; L247-A249 PolarHBondContact O-N 2.8Å; L247-L250 PolarHBondContact O-N 3.45Å; L247-I251 HydrophobicContact CD1-CD1 3.8Å; L247-I251 HydrophobicContact CD1-CG1 4.24Å; L247-I251 HydrophobicContact CG-CD1 4.01Å; L247-I251 VanDerWaalsContact O-CG1 3.31Å; L247-I251 WeakPolarHBondContact O-CG1 3.46Å; L247-I251 PolarHBondContact O-N 2.88Å; L247-I251 VanDerWaalsContact O-N 3.07Å
248	P	94.6	Very high	91.7	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-56.5	-47.2	170.7	-33.5	42.2	0	0	0	113.8	Y161 V164 A243 V244 L250 I251 I252 Y408	Y161-P248 HydrophobicContact CE1-CG 4.2Å; V164-P248 HydrophobicContact CG2-CB 3.61Å; V164-P248 HydrophobicContact CG2-CG 4.23Å; A243-P248 WeakPolarHBondContact O-CD 3.4Å; V244-P248 VanDerWaalsContact O-CG 3.3Å; V244-P248 WeakPolarHBondContact O-CG 3.05Å; P248-L250 VanDerWaalsContact C-N 3.32Å; P248-L250 PolarHBondContact O-N 3Å; P248-I251 PolarHBondContact O-N 3.16Å; P248-I252 HydrophobicContact CB-CD1 4.32Å; P248-I252 VanDerWaalsContact O-CB 3.25Å; P248-I252 WeakPolarHBondContact O-CB 3.38Å; P248-I252 VanDerWaalsContact O-CD1 3.31Å; P248-I252 WeakPolarHBondContact O-CD1 3.32Å; P248-I252 WeakPolarHBondContact O-CG1 3.33Å; P248-I252 PolarHBondContact O-N 3.04Å; P248-Y408 WeakPolarHBondContact CB-OH 3.36Å
249	A	93.4	Very high	91.6	Very high	15 Å²	15	44.6 Å²	44.6	12%	0.124	22%	0.223	C	C	.	.	H	α-helix	trans	-59.6	-41.1	179.9	0	0	0	0	0	112.1	F245 L247 T253 Y408	F245-A249 HydrophobicContact CD2-CB 4.47Å; F245-A249 HydrophobicContact CE2-CB 4.36Å; F245-A249 WeakPolarHBondContact O-CB 3.28Å; F245-A249 PolarHBondContact O-N 3.23Å; L247-A249 PolarHBondContact O-N 2.8Å; A249-T253 WeakPolarHBondContact O-CB 3.42Å; A249-T253 PolarHBondContact O-N 3.47Å; A249-T253 PolarHBondContact O-OG1 3.44Å; A249-Y408 HydrophobicContact CB-CE1 4.33Å
250	L	94.2	Very high	91.3	Very high	105 Å²	105	45.4 Å²	45.4	55%	0.55	23%	0.23	S	C	.	.	H	α-helix	trans	-62.5	-50.3	175.3	179.9	62.6	0	0	0	111.8	L246 L247 P248 I252 T253 I254	L246-L250 VanDerWaalsContact O-CB 3.25Å; L246-L250 WeakPolarHBondContact O-CB 3.25Å; L246-L250 PolarHBondContact O-N 3.26Å; L247-L250 PolarHBondContact O-N 3.45Å; P248-L250 VanDerWaalsContact C-N 3.32Å; P248-L250 PolarHBondContact O-N 3Å; L250-I252 PolarHBondContact O-N 3.08Å; L250-T253 PolarHBondContact O-N 2.92Å; L250-I254 HydrophobicContact CD1-CD1 3.8Å; L250-I254 HydrophobicContact CD1-CG1 4.28Å; L250-I254 HydrophobicContact CG-CD1 3.9Å; L250-I254 WeakPolarHBondContact O-CB 3.38Å; L250-I254 VanDerWaalsContact O-CG1 3.29Å; L250-I254 WeakPolarHBondContact O-CG1 3.36Å; L250-I254 PolarHBondContact O-N 3.35Å
251	I	94.3	Very high	91.3	Very high	55 Å²	55	53.1 Å²	53.1	28%	0.282	26%	0.258	S	S	.	.	H	α-helix	trans	-62	-47	180	-62.6	162.5	0	0	0	110.6	V164 V168 L247 P248 T253 I254 C255	V164-I251 HydrophobicContact CG1-CB 4.3Å; V164-I251 HydrophobicContact CG1-CD1 4.31Å; V164-I251 HydrophobicContact CG1-CG2 3.71Å; V168-I251 HydrophobicContact CG2-CG2 4.18Å; L247-I251 HydrophobicContact CD1-CD1 3.8Å; L247-I251 HydrophobicContact CD1-CG1 4.24Å; L247-I251 HydrophobicContact CG-CD1 4.01Å; L247-I251 VanDerWaalsContact O-CG1 3.31Å; L247-I251 WeakPolarHBondContact O-CG1 3.46Å; L247-I251 PolarHBondContact O-N 2.88Å; L247-I251 VanDerWaalsContact O-N 3.07Å; P248-I251 PolarHBondContact O-N 3.16Å; I251-T253 VanDerWaalsContact C-N 3.34Å; I251-T253 PolarHBondContact O-N 3.36Å; I251-I254 PolarHBondContact O-N 3.43Å; I251-C255 WeakPolarHBondContact O-CB 3.26Å; I251-C255 PolarHBondContact O-N 2.98Å; I251-C255 PolarHBondContact O-SG 3.48Å
252	I	92	Very high	91	Very high	0 Å²	0	55.9 Å²	55.9	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-58	-47	177.8	-72.1	163	0	0	0	110.3	I163 V164 T167 P248 L250 C255 Q256 V405 Y408	I163-I252 HydrophobicContact CG2-CD1 3.68Å; I163-I252 HydrophobicContact CG2-CG1 4.39Å; V164-I252 HydrophobicContact CG2-CD1 4.05Å; V164-I252 HydrophobicContact CG2-CG1 4.05Å; T167-I252 HydrophobicContact CG2-CG2 4.45Å; P248-I252 HydrophobicContact CB-CD1 4.32Å; P248-I252 VanDerWaalsContact O-CB 3.25Å; P248-I252 WeakPolarHBondContact O-CB 3.38Å; P248-I252 VanDerWaalsContact O-CD1 3.31Å; P248-I252 WeakPolarHBondContact O-CD1 3.32Å; P248-I252 WeakPolarHBondContact O-CG1 3.33Å; P248-I252 PolarHBondContact O-N 3.04Å; L250-I252 PolarHBondContact O-N 3.08Å; I252-C255 WeakPolarHBondContact O-CB 3.47Å; I252-C255 PolarHBondContact O-N 2.93Å; I252-Q256 WeakPolarHBondContact O-CG 3.48Å; I252-Q256 PolarHBondContact O-N 3.3Å; I252-V405 HydrophobicContact CG2-CB 4.01Å; I252-V405 HydrophobicContact CG2-CG1 3.79Å; I252-V405 HydrophobicContact CG2-CG2 3.26Å; I252-Y408 HydrophobicContact CD1-CD1 4.5Å; I252-Y408 HydrophobicContact CD1-CE1 4.43Å
253	T	91.1	Very high	90.4	Very high	60 Å²	60	54.2 Å²	54.2	37%	0.368	26%	0.259	S	S	.	.	H	α-helix	trans	-65.7	-45.3	-179	-61.3	0	0	0	0	111.9	A249 L250 I251 C255 Q256 I257	A249-T253 WeakPolarHBondContact O-CB 3.42Å; A249-T253 PolarHBondContact O-N 3.47Å; A249-T253 PolarHBondContact O-OG1 3.44Å; L250-T253 PolarHBondContact O-N 2.92Å; I251-T253 VanDerWaalsContact C-N 3.34Å; I251-T253 PolarHBondContact O-N 3.36Å; T253-C255 VanDerWaalsContact C-N 3.3Å; T253-C255 PolarHBondContact O-N 2.69Å; T253-Q256 PolarHBondContact O-N 3.1Å; T253-I257 HydrophobicContact CG2-CD1 3.86Å; T253-I257 HydrophobicContact CG2-CG1 4.44Å; T253-I257 WeakPolarHBondContact O-CG1 3.45Å; T253-I257 PolarHBondContact O-N 3.44Å
254	I	92.3	Very high	89.9	Confident	87 Å²	87	59 Å²	59	45%	0.446	28%	0.281	S	S	.	.	H	α-helix	trans	-58.9	-43.3	174.5	-69.3	167.6	0	0	0	110.4	L250 I251 I257 R258	L250-I254 HydrophobicContact CD1-CD1 3.8Å; L250-I254 HydrophobicContact CD1-CG1 4.28Å; L250-I254 HydrophobicContact CG-CD1 3.9Å; L250-I254 WeakPolarHBondContact O-CB 3.38Å; L250-I254 VanDerWaalsContact O-CG1 3.29Å; L250-I254 WeakPolarHBondContact O-CG1 3.36Å; L250-I254 PolarHBondContact O-N 3.35Å; I251-I254 PolarHBondContact O-N 3.43Å; I254-I257 PolarHBondContact O-N 3.49Å; I254-R258 WeakPolarHBondContact O-CG 3.41Å; I254-R258 PolarHBondContact O-N 3.34Å; I254-R258 VanDerWaalsContact O-N 3.09Å
255	C	91.4	Very high	89.5	Confident	10 Å²	10	62.8 Å²	62.8	7%	0.068	30%	0.301	C	S	.	.	H	α-helix	trans	-61.6	-45.9	175.2	-70.1	0	0	0	0	111.9	H171 I251 I252 T253 R258 I259	H171-C255 HydrophobicContact CB-CB 4.2Å; I251-C255 WeakPolarHBondContact O-CB 3.26Å; I251-C255 PolarHBondContact O-N 2.98Å; I251-C255 PolarHBondContact O-SG 3.48Å; I252-C255 WeakPolarHBondContact O-CB 3.47Å; I252-C255 PolarHBondContact O-N 2.93Å; T253-C255 VanDerWaalsContact C-N 3.3Å; T253-C255 PolarHBondContact O-N 2.69Å; C255-R258 PolarHBondContact O-N 3.19Å; C255-I259 WeakPolarHBondContact O-CB 3.29Å; C255-I259 WeakPolarHBondContact O-CD1 3.13Å; C255-I259 WeakPolarHBondContact O-CG1 3.24Å; C255-I259 PolarHBondContact O-N 2.93Å
256	Q	88.8	Confident	88.9	Confident	13 Å²	13	64.8 Å²	64.8	6%	0.061	31%	0.313	C	S	.	.	H	α-helix	trans	-63.6	-41.6	177.5	-64.4	-38	-71.2	0	0	112.7	I252 T253 R258 I259 F260 T401 L402 V405	I252-Q256 WeakPolarHBondContact O-CG 3.48Å; I252-Q256 PolarHBondContact O-N 3.3Å; T253-Q256 PolarHBondContact O-N 3.1Å; Q256-R258 VanDerWaalsContact C-N 3.32Å; Q256-R258 PolarHBondContact O-N 3.07Å; Q256-I259 PolarHBondContact O-N 3.43Å; Q256-F260 VanDerWaalsContact O-CB 3.3Å; Q256-F260 WeakPolarHBondContact O-CB 3.26Å; Q256-F260 PolarHBondContact O-N 3.42Å; Q256-T401 VanDerWaalsContact OE1-CB 3.24Å; Q256-T401 PolarHBondContact OE1-OG1 3.14Å; Q256-L402 HydrophobicContact CB-CD2 4.34Å; Q256-L402 HydrophobicContact CG-CD2 4.27Å; Q256-V405 HydrophobicContact CG-CG2 3.44Å; Q256-V405 VanDerWaalsContact CG-CG2 3.44Å
257	I	89.3	Confident	88.1	Confident	83 Å²	83	65.1 Å²	65.1	43%	0.426	31%	0.314	S	S	.	.	H	α-helix	trans	-61.3	-42	177.9	-69.1	167.1	0	0	0	110.5	T253 I254 R261	T253-I257 HydrophobicContact CG2-CD1 3.86Å; T253-I257 HydrophobicContact CG2-CG1 4.44Å; T253-I257 WeakPolarHBondContact O-CG1 3.45Å; T253-I257 PolarHBondContact O-N 3.44Å; I254-I257 PolarHBondContact O-N 3.49Å; I257-R261 WeakPolarHBondContact O-CB 3.43Å; I257-R261 VanDerWaalsContact O-CG 3.31Å; I257-R261 WeakPolarHBondContact O-CG 3.43Å; I257-R261 PolarHBondContact O-N 3.05Å
258	R	90	Very high	87	Confident	138 Å²	138	68 Å²	68	52%	0.521	32%	0.32	S	S	.	.	H	α-helix	trans	-67.7	-45.4	176	-67.8	-174.4	74.4	-174.5	3.2	112.2	H171 I254 C255 Q256 F260 R261 E262	H171-R258 PolarHBondContact CE1-NE 3.22Å; H171-R258 PolarHBondContact NE2-NH1 3.3Å; H171-R258 VanDerWaalsContact NE2-NH1 3.19Å; I254-R258 WeakPolarHBondContact O-CG 3.41Å; I254-R258 PolarHBondContact O-N 3.34Å; I254-R258 VanDerWaalsContact O-N 3.09Å; C255-R258 PolarHBondContact O-N 3.19Å; Q256-R258 VanDerWaalsContact C-N 3.32Å; Q256-R258 PolarHBondContact O-N 3.07Å; R258-F260 PolarHBondContact O-N 2.91Å; R258-R261 PolarHBondContact O-N 3.25Å; R258-E262 WeakPolarHBondContact O-CB 3.46Å; R258-E262 PolarHBondContact O-N 2.99Å
259	I	87.1	Confident	86	Confident	0 Å²	0	72.1 Å²	72.1	0%	0	34%	0.342	C	S	.	.	H	α-helix	trans	-57	-48.4	175.5	-72.5	163.9	0	0	0	110.6	R170 H171 I174 C255 Q256 E262 I263 V398	R170-I259 HydrophobicContact CB-CD1 4.42Å; H171-I259 HydrophobicContact CB-CD1 4.04Å; H171-I259 HydrophobicContact CB-CG1 4.17Å; I174-I259 HydrophobicContact CD1-CG2 3.96Å; C255-I259 WeakPolarHBondContact O-CB 3.29Å; C255-I259 WeakPolarHBondContact O-CD1 3.13Å; C255-I259 WeakPolarHBondContact O-CG1 3.24Å; C255-I259 PolarHBondContact O-N 2.93Å; Q256-I259 PolarHBondContact O-N 3.43Å; I259-E262 PolarHBondContact O-N 2.98Å; I259-I263 HydrophobicContact CG2-CD1 3.61Å; I259-I263 WeakPolarHBondContact O-CB 3.11Å; I259-I263 WeakPolarHBondContact O-CD1 3.3Å; I259-I263 VanDerWaalsContact O-CG1 3.24Å; I259-I263 WeakPolarHBondContact O-CG1 3.44Å; I259-I263 PolarHBondContact O-N 3.39Å; I259-V398 HydrophobicContact CG2-CG1 4.1Å; I259-V398 HydrophobicContact CG2-CG2 3.97Å
260	F	84.9	Confident	85.1	Confident	122 Å²	122	75.8 Å²	75.8	54%	0.535	36%	0.355	S	S	.	.	H	α-helix	trans	-65.3	-46	-178.9	-177	-94	0	0	0	112.2	Q256 R258 E262 I263 H264	Q256-F260 VanDerWaalsContact O-CB 3.3Å; Q256-F260 WeakPolarHBondContact O-CB 3.26Å; Q256-F260 PolarHBondContact O-N 3.42Å; R258-F260 PolarHBondContact O-N 2.91Å; F260-E262 PolarHBondContact O-N 2.97Å; F260-I263 PolarHBondContact O-N 3.5Å; F260-H264 WeakPolarHBondContact O-CB 3.45Å; F260-H264 PolarHBondContact O-N 3.48Å
261	R	86	Confident	84.3	Confident	170 Å²	170	74.6 Å²	74.6	64%	0.642	36%	0.356	S	S	*	.	H	α-helix	trans	-59.6	-46	175.9	-76.5	177.6	176.2	-174.3	-0.6	111.9	I257 R258 I263 H264 N265	I257-R261 WeakPolarHBondContact O-CB 3.43Å; I257-R261 VanDerWaalsContact O-CG 3.31Å; I257-R261 WeakPolarHBondContact O-CG 3.43Å; I257-R261 PolarHBondContact O-N 3.05Å; R258-R261 PolarHBondContact O-N 3.25Å; R261-I263 VanDerWaalsContact C-N 3.35Å; R261-I263 PolarHBondContact O-N 2.86Å; R261-H264 PolarHBondContact O-N 3.41Å; R261-N265 WeakPolarHBondContact O-CB 3.42Å; R261-N265 PolarHBondContact O-N 2.87Å; R261-N265 PolarHBondContact O-OD1 3.44Å
262	E	84.9	Confident	83.4	Confident	67 Å²	67	75.3 Å²	75.3	31%	0.313	36%	0.358	S	S	.	.	H	α-helix	trans	-61.8	-43.1	178.5	-173.7	60.9	-152.7	0	0	111.8	C175 R258 I259 F260 N265 N266	C175-E262 HydrophobicContact CB-CG 4.44Å; R258-E262 WeakPolarHBondContact O-CB 3.46Å; R258-E262 PolarHBondContact O-N 2.99Å; I259-E262 PolarHBondContact O-N 2.98Å; F260-E262 PolarHBondContact O-N 2.97Å; E262-N265 PolarHBondContact O-N 3.02Å; E262-N266 WeakPolarHBondContact O-CB 3.47Å; E262-N266 PolarHBondContact O-N 3.46Å; E262-N266 PolarHBondContact O-ND2 2.79Å; E262-N266 PolarHBondContact OE1-ND2 3.13Å
263	I	81.6	Confident	82.8	Confident	30 Å²	30	81.9 Å²	81.9	15%	0.154	38%	0.383	C	S	.	.	H	α-helix	trans	-66.2	-44.2	177.7	-72.2	164.3	0	0	0	111.3	I174 I259 F260 R261 N265 N266 I267 I390 V398	I174-I263 HydrophobicContact CG2-CD1 4.23Å; I174-I263 HydrophobicContact CG2-CG1 4.05Å; I259-I263 HydrophobicContact CG2-CD1 3.61Å; I259-I263 WeakPolarHBondContact O-CB 3.11Å; I259-I263 WeakPolarHBondContact O-CD1 3.3Å; I259-I263 VanDerWaalsContact O-CG1 3.24Å; I259-I263 WeakPolarHBondContact O-CG1 3.44Å; I259-I263 PolarHBondContact O-N 3.39Å; F260-I263 PolarHBondContact O-N 3.5Å; R261-I263 VanDerWaalsContact C-N 3.35Å; R261-I263 PolarHBondContact O-N 2.86Å; I263-N265 VanDerWaalsContact C-N 3.35Å; I263-N265 PolarHBondContact O-N 2.74Å; I263-N266 PolarHBondContact O-N 2.78Å; I263-I267 HydrophobicContact CG2-CD1 3.72Å; I263-I267 HydrophobicContact CG2-CG1 4.38Å; I263-I267 WeakPolarHBondContact O-CB 3.39Å; I263-I267 VanDerWaalsContact O-CG1 3.26Å; I263-I267 WeakPolarHBondContact O-CG1 3.21Å; I263-I267 PolarHBondContact O-N 3.24Å; I263-I390 HydrophobicContact CG2-CD1 4.35Å; I263-V398 HydrophobicContact CD1-CB 4.07Å; I263-V398 HydrophobicContact CD1-CG1 3.8Å; I263-V398 HydrophobicContact CD1-CG2 3.25Å
264	H	81.4	Confident	82.2	Confident	103 Å²	103	83.2 Å²	83.2	48%	0.477	39%	0.387	S	S	.	.	H	α-helix	trans	-58.8	-47.7	176.4	-176.9	-87.3	0	0	0	111	F260 R261 N266 I267 Y268	F260-H264 WeakPolarHBondContact O-CB 3.45Å; F260-H264 PolarHBondContact O-N 3.48Å; R261-H264 PolarHBondContact O-N 3.41Å; H264-N266 PolarHBondContact O-N 3.49Å; H264-I267 PolarHBondContact O-N 2.96Å; H264-Y268 WeakPolarHBondContact O-CB 3.38Å; H264-Y268 PolarHBondContact O-N 3.3Å
265	N	82.3	Confident	81.5	Confident	80 Å²	80	84.4 Å²	84.4	43%	0.428	39%	0.392	S	S	.	.	H	α-helix	trans	-60.9	-44.4	176.9	-67.3	-4.2	0	0	0	111.7	R261 E262 I263 I267 Y268 L269	R261-N265 WeakPolarHBondContact O-CB 3.42Å; R261-N265 PolarHBondContact O-N 2.87Å; R261-N265 PolarHBondContact O-OD1 3.44Å; E262-N265 PolarHBondContact O-N 3.02Å; I263-N265 VanDerWaalsContact C-N 3.35Å; I263-N265 PolarHBondContact O-N 2.74Å; N265-I267 PolarHBondContact O-N 2.73Å; N265-Y268 PolarHBondContact O-N 2.82Å; N265-L269 VanDerWaalsContact O-CB 3.26Å; N265-L269 WeakPolarHBondContact O-CB 3.48Å; N265-L269 VanDerWaalsContact O-CG 3.28Å; N265-L269 WeakPolarHBondContact O-CG 3.24Å; N265-L269 PolarHBondContact O-N 2.83Å
266	N	77.5	Confident	81	Confident	62 Å²	62	89 Å²	89	33%	0.332	41%	0.413	S	S	.	.	H	α-helix	trans	-67.8	-30.7	176.9	-82.5	-82.1	0	0	0	113.4	E262 I263 H264 K270 I390	E262-N266 WeakPolarHBondContact O-CB 3.47Å; E262-N266 PolarHBondContact O-N 3.46Å; E262-N266 PolarHBondContact O-ND2 2.79Å; E262-N266 PolarHBondContact OE1-ND2 3.13Å; I263-N266 PolarHBondContact O-N 2.78Å; H264-N266 PolarHBondContact O-N 3.49Å; N266-K270 WeakPolarHBondContact O-CB 3.37Å; N266-K270 PolarHBondContact O-N 3.29Å; N266-I390 HydrophobicContact CB-CD1 4.01Å
267	I	77.3	Confident	80.7	Confident	94 Å²	94	91.2 Å²	91.2	48%	0.482	43%	0.434	S	S	.	.	H	α-helix	trans	-69.7	-49.4	172.3	-70.3	169.2	0	0	0	110	I263 H264 N265 K270 S271 I390	I263-I267 HydrophobicContact CG2-CD1 3.72Å; I263-I267 HydrophobicContact CG2-CG1 4.38Å; I263-I267 WeakPolarHBondContact O-CB 3.39Å; I263-I267 VanDerWaalsContact O-CG1 3.26Å; I263-I267 WeakPolarHBondContact O-CG1 3.21Å; I263-I267 PolarHBondContact O-N 3.24Å; H264-I267 PolarHBondContact O-N 2.96Å; N265-I267 PolarHBondContact O-N 2.73Å; I267-K270 PolarHBondContact O-N 2.94Å; I267-S271 PolarHBondContact O-N 2.89Å; I267-I390 HydrophobicContact CD1-CD1 4.31Å; I267-I390 HydrophobicContact CG1-CD1 3.56Å
268	Y	73.7	Confident	80.3	Confident	133 Å²	133	91.9 Å²	91.9	52%	0.522	44%	0.435	S	S	.	.	H	α-helix	trans	-61.2	-54.9	-179.2	-175.7	-92.8	0	0	0	111.8	H264 N265 K270 S271 E272	H264-Y268 WeakPolarHBondContact O-CB 3.38Å; H264-Y268 PolarHBondContact O-N 3.3Å; N265-Y268 PolarHBondContact O-N 2.82Å; Y268-K270 PolarHBondContact O-N 3.22Å; Y268-K270 VanDerWaalsContact O-N 3.14Å; Y268-S271 WeakPolarHBondContact O-CA 3.27Å; Y268-S271 WeakPolarHBondContact O-CB 3.35Å; Y268-S271 PolarHBondContact O-N 3.47Å; Y268-E272 HydrophobicContact CE1-CG 4.13Å; Y268-E272 WeakPolarHBondContact CE1-OE2 3.19Å; Y268-E272 PolarHBondContact O-N 3.34Å
269	L	73.8	Confident	80.1	Confident	87 Å²	87	90.7 Å²	90.7	46%	0.455	44%	0.438	S	S	.	.	H	α-helix	trans	-64.7	-17.5	177.2	-66.7	169.2	0	0	0	113.2	N265 R273	N265-L269 VanDerWaalsContact O-CB 3.26Å; N265-L269 WeakPolarHBondContact O-CB 3.48Å; N265-L269 VanDerWaalsContact O-CG 3.28Å; N265-L269 WeakPolarHBondContact O-CG 3.24Å; N265-L269 PolarHBondContact O-N 2.83Å; L269-R273 WeakPolarHBondContact O-CG 3.47Å; L269-R273 PolarHBondContact O-NE 3.27Å; L269-R273 PolarHBondContact O-NH2 3.28Å
270	K	74.3	Confident	80.2	Confident	93 Å²	93	97.2 Å²	97.2	40%	0.404	47%	0.467	S	S	.	.	H	α-helix	trans	-82.1	-40.1	168.8	179.9	-177.5	174.3	-170.8	0	111.2	N266 I267 Y268 R273 I274	N266-K270 WeakPolarHBondContact O-CB 3.37Å; N266-K270 PolarHBondContact O-N 3.29Å; I267-K270 PolarHBondContact O-N 2.94Å; Y268-K270 PolarHBondContact O-N 3.22Å; Y268-K270 VanDerWaalsContact O-N 3.14Å; K270-R273 PolarHBondContact O-N 3.44Å; K270-I274 HydrophobicContact CD-CD1 4.43Å; K270-I274 HydrophobicContact CG-CD1 3.88Å; K270-I274 HydrophobicContact CG-CG1 4.47Å; K270-I274 WeakPolarHBondContact O-CG1 3.33Å; K270-I274 PolarHBondContact O-N 3.46Å
271	S	75.7	Confident	80.3	Confident	79 Å²	79	98.8 Å²	98.8	55%	0.552	47%	0.469	S	S	*	.	H	α-helix	trans	-59.8	-48.6	177.1	-159.9	0	0	0	0	111.1	I267 Y268 R273 I274 M275	I267-S271 PolarHBondContact O-N 2.89Å; Y268-S271 WeakPolarHBondContact O-CA 3.27Å; Y268-S271 WeakPolarHBondContact O-CB 3.35Å; Y268-S271 PolarHBondContact O-N 3.47Å; S271-R273 PolarHBondContact O-N 2.96Å; S271-I274 PolarHBondContact O-N 3.35Å; S271-M275 WeakPolarHBondContact O-CB 3.29Å; S271-M275 PolarHBondContact O-N 3.42Å
272	E	76.4	Confident	80.3	Confident	71 Å²	71	93.4 Å²	93.4	33%	0.332	46%	0.458	S	S	.	.	H	α-helix	trans	-60.5	-46.4	175.2	-69.1	-166	107.5	0	0	112.5	Y268 I274 M275 M276	Y268-E272 HydrophobicContact CE1-CG 4.13Å; Y268-E272 WeakPolarHBondContact CE1-OE2 3.19Å; Y268-E272 PolarHBondContact O-N 3.34Å; E272-I274 VanDerWaalsContact C-N 3.3Å; E272-I274 PolarHBondContact O-N 2.91Å; E272-M275 PolarHBondContact O-N 3.35Å; E272-M276 WeakPolarHBondContact O-CB 3.33Å; E272-M276 VanDerWaalsContact O-CG 3.27Å; E272-M276 WeakPolarHBondContact O-CG 3.47Å; E272-M276 PolarHBondContact O-N 2.89Å
273	R	79.7	Confident	80.5	Confident	137 Å²	137	95 Å²	95	52%	0.517	47%	0.465	S	S	.	.	H	α-helix	trans	-63.5	-33.3	178.8	-79.5	-177.6	-70.4	175.4	-4.2	113.2	L269 K270 S271 A277	L269-R273 WeakPolarHBondContact O-CG 3.47Å; L269-R273 PolarHBondContact O-NE 3.27Å; L269-R273 PolarHBondContact O-NH2 3.28Å; K270-R273 PolarHBondContact O-N 3.44Å; S271-R273 PolarHBondContact O-N 2.96Å; R273-A277 VanDerWaalsContact O-CB 3.28Å; R273-A277 WeakPolarHBondContact O-CB 3.43Å; R273-A277 PolarHBondContact O-N 2.9Å; R273-A277 VanDerWaalsContact O-N 3.14Å
274	I	77.1	Confident	81	Confident	89 Å²	89	97.5 Å²	97.5	46%	0.456	48%	0.478	S	S	.	.	H	α-helix	trans	-70.4	-46.3	172.9	-70.9	170.7	0	0	0	110.4	K270 S271 E272 M276 A277 E278	K270-I274 HydrophobicContact CD-CD1 4.43Å; K270-I274 HydrophobicContact CG-CD1 3.88Å; K270-I274 HydrophobicContact CG-CG1 4.47Å; K270-I274 WeakPolarHBondContact O-CG1 3.33Å; K270-I274 PolarHBondContact O-N 3.46Å; S271-I274 PolarHBondContact O-N 3.35Å; E272-I274 VanDerWaalsContact C-N 3.3Å; E272-I274 PolarHBondContact O-N 2.91Å; I274-M276 PolarHBondContact O-N 3.31Å; I274-A277 PolarHBondContact O-N 3.26Å; I274-E278 PolarHBondContact O-N 3.25Å
275	M	79.1	Confident	81.2	Confident	111 Å²	111	96.9 Å²	96.9	55%	0.547	48%	0.478	S	S	.	.	H	α-helix	trans	-58.4	-47.5	178	-174.9	-178.8	70.5	0	0	111.7	S271 E272 A277 E278 L279	S271-M275 WeakPolarHBondContact O-CB 3.29Å; S271-M275 PolarHBondContact O-N 3.42Å; E272-M275 PolarHBondContact O-N 3.35Å; M275-A277 VanDerWaalsContact C-N 3.33Å; M275-A277 PolarHBondContact O-N 2.99Å; M275-E278 PolarHBondContact O-N 3.44Å; M275-L279 WeakPolarHBondContact O-CB 3.37Å; M275-L279 PolarHBondContact O-N 2.92Å
276	M	79.9	Confident	81.3	Confident	107 Å²	107	98.4 Å²	98.4	53%	0.527	49%	0.485	S	S	.	.	H	α-helix	trans	-65.1	-34.4	177.5	-67	-65.9	-178.8	0	0	112.5	E272 I274 K280	E272-M276 WeakPolarHBondContact O-CB 3.33Å; E272-M276 VanDerWaalsContact O-CG 3.27Å; E272-M276 WeakPolarHBondContact O-CG 3.47Å; E272-M276 PolarHBondContact O-N 2.89Å; I274-M276 PolarHBondContact O-N 3.31Å; M276-K280 WeakPolarHBondContact O-CB 3.39Å; M276-K280 PolarHBondContact O-N 2.85Å
277	A	82.3	Confident	81.7	Confident	59 Å²	59	103.7 Å²	103.7	49%	0.488	50%	0.5	S	S	.	.	H	α-helix	trans	-68.6	-45.3	175.8	0	0	0	0	0	112.3	R273 I274 M275 K280 R281	R273-A277 VanDerWaalsContact O-CB 3.28Å; R273-A277 WeakPolarHBondContact O-CB 3.43Å; R273-A277 PolarHBondContact O-N 2.9Å; R273-A277 VanDerWaalsContact O-N 3.14Å; I274-A277 PolarHBondContact O-N 3.26Å; M275-A277 VanDerWaalsContact C-N 3.33Å; M275-A277 PolarHBondContact O-N 2.99Å; A277-K280 PolarHBondContact O-N 2.82Å; A277-R281 VanDerWaalsContact O-CB 3.27Å; A277-R281 WeakPolarHBondContact O-CB 3.12Å; A277-R281 PolarHBondContact O-N 3.24Å
278	E	82.3	Confident	82.2	Confident	97 Å²	97	106 Å²	106	45%	0.453	51%	0.507	S	S	.	.	H	α-helix	trans	-68.6	-34.8	175.7	-66.7	-66.6	176.3	0	0	111.8	I274 M275 R281 S282	I274-E278 PolarHBondContact O-N 3.25Å; M275-E278 PolarHBondContact O-N 3.44Å; E278-R281 PolarHBondContact O-N 3.43Å; E278-R281 IonicContact OE1-NH1 3.49Å; E278-R281 PolarHBondContact OE1-NH1 3.11Å; E278-R281 WeakPolarHBondContact OE2-CD 3.39Å; E278-R281 IonicContact OE2-CZ 3.04Å; E278-R281 IonicContact OE2-NE 3.41Å; E278-R281 IonicContact OE2-NH1 2.78Å; E278-R281 PolarHBondContact OE2-NH1 3.05Å; E278-S282 WeakPolarHBondContact O-CB 3.49Å; E278-S282 PolarHBondContact O-N 3.36Å
279	L	85.6	Confident	82.6	Confident	113 Å²	113	104.1 Å²	104.1	59%	0.592	50%	0.503	S	S	*	.	H	α-helix	trans	-60.4	-52.6	173.1	-163.5	82.5	0	0	0	110.9	M275 R281 S282 E283	M275-L279 WeakPolarHBondContact O-CB 3.37Å; M275-L279 PolarHBondContact O-N 2.92Å; L279-R281 VanDerWaalsContact C-N 3.29Å; L279-R281 PolarHBondContact O-N 2.88Å; L279-S282 PolarHBondContact O-N 2.85Å; L279-S282 VanDerWaalsContact O-N 3.1Å; L279-S282 PolarHBondContact O-OG 3.26Å; L279-E283 PolarHBondContact O-N 2.91Å
280	K	88.2	Confident	83	Confident	137 Å²	137	101.5 Å²	101.5	60%	0.596	50%	0.497	S	S	*	.	H	α-helix	trans	-63.3	-34	178.1	-168.3	167.8	-172.6	170.7	0	112.6	M276 A277 I284	M276-K280 WeakPolarHBondContact O-CB 3.39Å; M276-K280 PolarHBondContact O-N 2.85Å; A277-K280 PolarHBondContact O-N 2.82Å; K280-I284 HydrophobicContact CG-CD1 4.24Å; K280-I284 WeakPolarHBondContact O-CD1 3.34Å; K280-I284 VanDerWaalsContact O-CG1 3.26Å; K280-I284 WeakPolarHBondContact O-CG1 3.4Å; K280-I284 PolarHBondContact O-N 3.34Å
281	R	88.3	Confident	83.5	Confident	156 Å²	156	102.2 Å²	102.2	59%	0.589	51%	0.505	S	S	*	.	H	α-helix	trans	-64.9	-41.4	172.5	-175.3	-164.6	-177.5	-171.5	-0.1	111.7	A277 E278 L279 I284 L285	A277-R281 VanDerWaalsContact O-CB 3.27Å; A277-R281 WeakPolarHBondContact O-CB 3.12Å; A277-R281 PolarHBondContact O-N 3.24Å; E278-R281 PolarHBondContact O-N 3.43Å; E278-R281 IonicContact OE1-NH1 3.49Å; E278-R281 PolarHBondContact OE1-NH1 3.11Å; E278-R281 WeakPolarHBondContact OE2-CD 3.39Å; E278-R281 IonicContact OE2-CZ 3.04Å; E278-R281 IonicContact OE2-NE 3.41Å; E278-R281 IonicContact OE2-NH1 2.78Å; E278-R281 PolarHBondContact OE2-NH1 3.05Å; L279-R281 VanDerWaalsContact C-N 3.29Å; L279-R281 PolarHBondContact O-N 2.88Å; R281-I284 PolarHBondContact O-N 3.14Å; R281-L285 WeakPolarHBondContact O-CB 3.32Å; R281-L285 PolarHBondContact O-N 3.3Å
282	S	85.9	Confident	84	Confident	57 Å²	57	105.9 Å²	105.9	40%	0.399	51%	0.507	S	S	.	.	H	α-helix	trans	-67.6	-39	177.4	74.8	0	0	0	0	112.1	E278 L279 L285 L286	E278-S282 WeakPolarHBondContact O-CB 3.49Å; E278-S282 PolarHBondContact O-N 3.36Å; L279-S282 PolarHBondContact O-N 2.85Å; L279-S282 VanDerWaalsContact O-N 3.1Å; L279-S282 PolarHBondContact O-OG 3.26Å; S282-L285 PolarHBondContact O-N 2.94Å; S282-L286 WeakPolarHBondContact O-CB 3.22Å; S282-L286 WeakPolarHBondContact O-CG 3.14Å; S282-L286 PolarHBondContact O-N 3.29Å
283	E	89.3	Confident	84.4	Confident	100 Å²	100	108 Å²	108	47%	0.467	52%	0.515	S	S	.	.	H	α-helix	trans	-59.7	-48.4	172.3	-167.5	-157.9	154.8	0	0	112.1	L279 L285 L286 R287	L279-E283 PolarHBondContact O-N 2.91Å; E283-L285 VanDerWaalsContact C-N 3.33Å; E283-L285 PolarHBondContact O-N 2.88Å; E283-L286 PolarHBondContact O-N 3.41Å; E283-R287 PolarHBondContact O-N 3.08Å; E283-R287 IonicContact OE1-NE 3.44Å
284	I	90.8	Very high	84.5	Confident	82 Å²	82	106.5 Å²	106.5	42%	0.421	51%	0.514	S	S	.	.	H	α-helix	trans	-59.9	-44	176.5	-70.6	164.5	0	0	0	110.7	K280 R281 L286 R287 F288	K280-I284 HydrophobicContact CG-CD1 4.24Å; K280-I284 WeakPolarHBondContact O-CD1 3.34Å; K280-I284 VanDerWaalsContact O-CG1 3.26Å; K280-I284 WeakPolarHBondContact O-CG1 3.4Å; K280-I284 PolarHBondContact O-N 3.34Å; R281-I284 PolarHBondContact O-N 3.14Å; I284-L286 PolarHBondContact O-N 3.44Å; I284-R287 PolarHBondContact O-N 3.07Å; I284-F288 HydrophobicContact CG2-CD2 3.81Å; I284-F288 HydrophobicContact CG2-CE2 3.9Å; I284-F288 WeakPolarHBondContact O-CD2 3.31Å; I284-F288 PolarHBondContact O-N 2.92Å
285	L	85	Confident	84.6	Confident	91 Å²	91	105 Å²	105	48%	0.476	51%	0.507	S	S	.	.	H	α-helix	trans	-66.6	-36.1	180	-169.4	141.8	0	0	0	112.2	R281 S282 E283 Q289	R281-L285 WeakPolarHBondContact O-CB 3.32Å; R281-L285 PolarHBondContact O-N 3.3Å; S282-L285 PolarHBondContact O-N 2.94Å; E283-L285 VanDerWaalsContact C-N 3.33Å; E283-L285 PolarHBondContact O-N 2.88Å; L285-Q289 HydrophobicContact CD2-CG 4.48Å; L285-Q289 WeakPolarHBondContact O-CG 3.48Å; L285-Q289 PolarHBondContact O-N 2.76Å
286	L	85.1	Confident	84.7	Confident	111 Å²	111	103.4 Å²	103.4	58%	0.581	50%	0.498	S	S	*	.	H	α-helix	trans	-66.2	-43.1	171.7	-74.6	167.4	0	0	0	112.1	S282 E283 I284 F288 Q289 G290	S282-L286 WeakPolarHBondContact O-CB 3.22Å; S282-L286 WeakPolarHBondContact O-CG 3.14Å; S282-L286 PolarHBondContact O-N 3.29Å; E283-L286 PolarHBondContact O-N 3.41Å; I284-L286 PolarHBondContact O-N 3.44Å; L286-F288 PolarHBondContact O-N 3.23Å; L286-Q289 PolarHBondContact O-N 2.74Å; L286-G290 PolarHBondContact O-N 3.31Å
287	R	86.9	Confident	84.7	Confident	173 Å²	173	105.7 Å²	105.7	65%	0.653	50%	0.501	S	S	*	.	H	α-helix	trans	-58.4	-46.9	173.4	-83.1	-177.9	172.5	-100.6	3.4	111.9	E283 I284 Q289 G290 L291	E283-R287 PolarHBondContact O-N 3.08Å; E283-R287 IonicContact OE1-NE 3.44Å; I284-R287 PolarHBondContact O-N 3.07Å; R287-Q289 VanDerWaalsContact C-N 3.34Å; R287-Q289 PolarHBondContact O-N 3.49Å; R287-G290 PolarHBondContact O-N 3.31Å; R287-G290 VanDerWaalsContact O-N 3.17Å; R287-L291 WeakPolarHBondContact O-CG 3.34Å; R287-L291 PolarHBondContact O-N 3.15Å
288	F	87.1	Confident	84.6	Confident	142 Å²	142	109 Å²	109	62%	0.623	51%	0.506	S	S	*	.	H	α-helix	trans	-62.9	-37.1	176.1	-89.2	-73.4	0	0	0	112.9	I284 L286 R292	I284-F288 HydrophobicContact CG2-CD2 3.81Å; I284-F288 HydrophobicContact CG2-CE2 3.9Å; I284-F288 WeakPolarHBondContact O-CD2 3.31Å; I284-F288 PolarHBondContact O-N 2.92Å; L286-F288 PolarHBondContact O-N 3.23Å; F288-R292 WeakPolarHBondContact O-CB 3.42Å; F288-R292 PolarHBondContact O-N 2.85Å
289	Q	82.1	Confident	84.3	Confident	95 Å²	95	111.5 Å²	111.5	44%	0.444	51%	0.511	S	S	.	.	H	α-helix	trans	-69.3	-30.6	173.6	-74.7	-176.1	5.1	0	0	113.3	L285 L286 R287 K293	L285-Q289 HydrophobicContact CD2-CG 4.48Å; L285-Q289 WeakPolarHBondContact O-CG 3.48Å; L285-Q289 PolarHBondContact O-N 2.76Å; L286-Q289 PolarHBondContact O-N 2.74Å; R287-Q289 VanDerWaalsContact C-N 3.34Å; R287-Q289 PolarHBondContact O-N 3.49Å; Q289-K293 WeakPolarHBondContact O-CG 3.19Å; Q289-K293 PolarHBondContact O-N 2.93Å
290	G	82	Confident	83.8	Confident	32 Å²	32	112.1 Å²	112.1	33%	0.33	51%	0.511	S	S	.	.	H	α-helix	trans	-63.2	-59.1	171.2	0	0	0	0	0	111.2	L286 R287 R292 K293 E294	L286-G290 PolarHBondContact O-N 3.31Å; R287-G290 PolarHBondContact O-N 3.31Å; R287-G290 VanDerWaalsContact O-N 3.17Å; G290-R292 VanDerWaalsContact C-N 3.28Å; G290-R292 PolarHBondContact O-N 3.31Å; G290-K293 WeakPolarHBondContact O-CA 3.37Å; G290-K293 WeakPolarHBondContact O-CB 3.5Å; G290-K293 PolarHBondContact O-N 3.27Å; G290-E294 PolarHBondContact O-N 3.21Å
291	L	85	Confident	83.1	Confident	108 Å²	108	114.1 Å²	114.1	57%	0.565	52%	0.515	S	S	*	.	H	α-helix	trans	-55.2	-40.7	179.6	-67.4	170.2	0	0	0	112.4	R287 K293 E294 D295	R287-L291 WeakPolarHBondContact O-CG 3.34Å; R287-L291 PolarHBondContact O-N 3.15Å; L291-K293 VanDerWaalsContact C-N 3.35Å; L291-K293 PolarHBondContact O-N 2.97Å; L291-E294 PolarHBondContact O-N 2.95Å; L291-D295 PolarHBondContact O-N 3.45Å
292	R	85.2	Confident	82.1	Confident	156 Å²	156	108.5 Å²	108.5	59%	0.589	51%	0.506	S	S	*	.	H	α-helix	trans	-66.7	-33.9	177.5	-151.1	-164.8	83.4	-166	4.4	113	F288 G290 E294 E296	F288-R292 WeakPolarHBondContact O-CB 3.42Å; F288-R292 PolarHBondContact O-N 2.85Å; G290-R292 VanDerWaalsContact C-N 3.28Å; G290-R292 PolarHBondContact O-N 3.31Å; R292-E294 VanDerWaalsContact C-N 3.33Å; R292-E296 IonicContact CZ-OE1 2.99Å; R292-E296 IonicContact NE-OE1 2.68Å; R292-E296 PolarHBondContact NE-OE1 3.46Å; R292-E296 IonicContact NH2-OE1 3.79Å; R292-E296 PolarHBondContact NH2-OE1 3.04Å; R292-E296 IonicContact NH2-OE2 3.25Å; R292-E296 WeakPolarHBondContact O-CB 3.09Å; R292-E296 WeakPolarHBondContact O-CG 3.24Å; R292-E296 PolarHBondContact O-N 3.44Å
293	K	84.8	Confident	81.2	Confident	114 Å²	114	115 Å²	115	50%	0.496	52%	0.521	S	S	.	.	H	α-helix	trans	-72.4	-27	174.4	-76.8	174.1	178.6	176.1	0	112.5	Q289 G290 L291 R297	Q289-K293 WeakPolarHBondContact O-CG 3.19Å; Q289-K293 PolarHBondContact O-N 2.93Å; G290-K293 WeakPolarHBondContact O-CA 3.37Å; G290-K293 WeakPolarHBondContact O-CB 3.5Å; G290-K293 PolarHBondContact O-N 3.27Å; L291-K293 VanDerWaalsContact C-N 3.35Å; L291-K293 PolarHBondContact O-N 2.97Å; K293-R297 WeakPolarHBondContact O-CB 3.38Å; K293-R297 VanDerWaalsContact O-CD 3.28Å; K293-R297 WeakPolarHBondContact O-CD 3.28Å; K293-R297 WeakPolarHBondContact O-CG 3.38Å; K293-R297 PolarHBondContact O-N 3.31Å; K293-R297 VanDerWaalsContact O-N 3.1Å
294	E	81.6	Confident	79.9	Confident	107 Å²	107	117.5 Å²	117.5	50%	0.5	53%	0.533	S	S	.	.	H	α-helix	trans	-73.8	-48	174.3	-70.1	171.1	150.6	0	0	110.2	G290 L291 R292 E296 R297 E298	G290-E294 PolarHBondContact O-N 3.21Å; L291-E294 PolarHBondContact O-N 2.95Å; R292-E294 VanDerWaalsContact C-N 3.33Å; E294-E296 VanDerWaalsContact C-N 3.33Å; E294-E296 PolarHBondContact O-N 3.3Å; E294-R297 PolarHBondContact O-N 2.79Å; E294-R297 VanDerWaalsContact O-N 3.07Å; E294-E298 WeakPolarHBondContact O-CG 3.3Å; E294-E298 PolarHBondContact O-N 3.38Å
295	D	81.1	Confident	78.4	Confident	58 Å²	58	116.6 Å²	116.6	31%	0.31	54%	0.538	S	S	.	.	H	α-helix	trans	-56.5	-41.1	171.1	179	42.3	0	0	0	113	L291 R299	L291-D295 PolarHBondContact O-N 3.45Å; D295-R299 VanDerWaalsContact CG-NH1 3.3Å; D295-R299 WeakPolarHBondContact O-CG 3.49Å; D295-R299 PolarHBondContact O-N 3.5Å; D295-R299 VanDerWaalsContact O-N 3.14Å; D295-R299 IonicContact OD1-CZ 2.73Å; D295-R299 IonicContact OD1-NE 2.82Å; D295-R299 PolarHBondContact OD1-NE 2.98Å; D295-R299 IonicContact OD1-NH1 3.89Å; D295-R299 PolarHBondContact OD1-NH1 3.29Å; D295-R299 IonicContact OD1-NH2 2.73Å; D295-R299 PolarHBondContact OD1-NH2 2.95Å; D295-R299 IonicContact OD2-CZ 2.74Å; D295-R299 IonicContact OD2-NH1 2.87Å; D295-R299 PolarHBondContact OD2-NH1 3.23Å; D295-R299 IonicContact OD2-NH2 2.82Å; D295-R299 PolarHBondContact OD2-NH2 3.42Å
296	E	80.5	Confident	77	Confident	77 Å²	77	117.3 Å²	117.3	36%	0.36	55%	0.546	S	S	.	.	H	α-helix	trans	-60.4	-47.9	171.4	-77.8	164.8	-169.1	0	0	112.1	R292 E294 R299 E300	R292-E296 IonicContact CZ-OE1 2.99Å; R292-E296 IonicContact NE-OE1 2.68Å; R292-E296 PolarHBondContact NE-OE1 3.46Å; R292-E296 IonicContact NH2-OE1 3.79Å; R292-E296 PolarHBondContact NH2-OE1 3.04Å; R292-E296 IonicContact NH2-OE2 3.25Å; R292-E296 WeakPolarHBondContact O-CB 3.09Å; R292-E296 WeakPolarHBondContact O-CG 3.24Å; R292-E296 PolarHBondContact O-N 3.44Å; E294-E296 VanDerWaalsContact C-N 3.33Å; E294-E296 PolarHBondContact O-N 3.3Å; E296-R299 PolarHBondContact O-N 3.34Å; E296-E300 WeakPolarHBondContact O-CG 3.43Å; E296-E300 PolarHBondContact O-N 3.31Å
297	R	80.3	Confident	75.5	Confident	154 Å²	154	115.1 Å²	115.1	58%	0.581	55%	0.55	S	S	*	*	H	α-helix	trans	-66.7	-36.3	179.7	-76.1	165.3	173.2	179.1	-4.7	113.4	K293 E294 E300 R301	K293-R297 WeakPolarHBondContact O-CB 3.38Å; K293-R297 VanDerWaalsContact O-CD 3.28Å; K293-R297 WeakPolarHBondContact O-CD 3.28Å; K293-R297 WeakPolarHBondContact O-CG 3.38Å; K293-R297 PolarHBondContact O-N 3.31Å; K293-R297 VanDerWaalsContact O-N 3.1Å; E294-R297 PolarHBondContact O-N 2.79Å; E294-R297 VanDerWaalsContact O-N 3.07Å; R297-E300 PolarHBondContact O-N 3.35Å; R297-R301 WeakPolarHBondContact O-CG 3.47Å; R297-R301 PolarHBondContact O-N 3.06Å
298	E	79	Confident	73.6	Confident	130 Å²	130	118 Å²	118	61%	0.607	56%	0.561	S	S	*	*	H	α-helix	trans	-68.9	-39.4	177	-71.9	-169.7	155.9	0	0	111.3	E294 E300 R301 G302	E294-E298 WeakPolarHBondContact O-CG 3.3Å; E294-E298 PolarHBondContact O-N 3.38Å; E298-E300 VanDerWaalsContact C-N 3.34Å; E298-E300 PolarHBondContact O-N 2.91Å; E298-R301 PolarHBondContact O-N 3.26Å; E298-G302 PolarHBondContact O-N 3.12Å
299	R	76.6	Confident	71.7	Confident	148 Å²	148	115 Å²	115	56%	0.558	56%	0.563	S	S	*	*	H	α-helix	trans	-63.8	-36.4	170.9	-71.2	-179.6	-173.8	126.5	13.6	112.9	D295 E296 R303	D295-R299 VanDerWaalsContact CG-NH1 3.3Å; D295-R299 WeakPolarHBondContact O-CG 3.49Å; D295-R299 PolarHBondContact O-N 3.5Å; D295-R299 VanDerWaalsContact O-N 3.14Å; D295-R299 IonicContact OD1-CZ 2.73Å; D295-R299 IonicContact OD1-NE 2.82Å; D295-R299 PolarHBondContact OD1-NE 2.98Å; D295-R299 IonicContact OD1-NH1 3.89Å; D295-R299 PolarHBondContact OD1-NH1 3.29Å; D295-R299 IonicContact OD1-NH2 2.73Å; D295-R299 PolarHBondContact OD1-NH2 2.95Å; D295-R299 IonicContact OD2-CZ 2.74Å; D295-R299 IonicContact OD2-NH1 2.87Å; D295-R299 PolarHBondContact OD2-NH1 3.23Å; D295-R299 IonicContact OD2-NH2 2.82Å; D295-R299 PolarHBondContact OD2-NH2 3.42Å; E296-R299 PolarHBondContact O-N 3.34Å; R299-R303 WeakPolarHBondContact O-CB 3.24Å; R299-R303 WeakPolarHBondContact O-CG 3.06Å; R299-R303 PolarHBondContact O-N 3.48Å
300	E	75.7	Confident	69.9	Low	126 Å²	126	114.3 Å²	114.3	59%	0.589	58%	0.581	S	S	*	*	H	α-helix	trans	-66.5	-44.4	173.3	-74.4	-175.9	157.2	0	0	112.3	E296 R297 E298 R303 Q304	E296-E300 WeakPolarHBondContact O-CG 3.43Å; E296-E300 PolarHBondContact O-N 3.31Å; R297-E300 PolarHBondContact O-N 3.35Å; E298-E300 VanDerWaalsContact C-N 3.34Å; E298-E300 PolarHBondContact O-N 2.91Å; E300-R303 PolarHBondContact O-N 3.01Å; E300-Q304 PolarHBondContact O-N 2.74Å
301	R	73	Confident	68.2	Low	180 Å²	180	116.4 Å²	116.4	68%	0.679	60%	0.602	S	S	*	*	H	α-helix	trans	-60.6	-45.1	173.6	-75.2	176.4	176.4	175.1	-1.3	112	R297 E298 R303 Q304 A305	R297-R301 WeakPolarHBondContact O-CG 3.47Å; R297-R301 PolarHBondContact O-N 3.06Å; E298-R301 PolarHBondContact O-N 3.26Å; R301-R303 VanDerWaalsContact C-N 3.34Å; R301-R303 PolarHBondContact O-N 3.47Å; R301-Q304 PolarHBondContact O-N 3.28Å; R301-A305 PolarHBondContact O-N 3.12Å
302	G	68.1	Low	66	Low	38 Å²	38	114.8 Å²	114.8	39%	0.392	61%	0.612	S	S	.	*	H	α-helix	trans	-58.4	-44.8	175.6	0	0	0	0	0	112.1	E298 A305 T306	E298-G302 PolarHBondContact O-N 3.12Å; G302-A305 PolarHBondContact O-N 2.95Å; G302-T306 PolarHBondContact O-N 3.38Å; G302-T306 PolarHBondContact O-OG1 2.92Å
303	R	67	Low	63.7	Low	193 Å²	193	115.7 Å²	115.7	73%	0.728	62%	0.623	S	S	*	*	H	α-helix	trans	-61.4	-43.9	173.9	-79.1	175.4	168.6	168.9	-3.2	112.6	R299 E300 R301 A305 T306 G307	R299-R303 WeakPolarHBondContact O-CB 3.24Å; R299-R303 WeakPolarHBondContact O-CG 3.06Å; R299-R303 PolarHBondContact O-N 3.48Å; E300-R303 PolarHBondContact O-N 3.01Å; R301-R303 VanDerWaalsContact C-N 3.34Å; R301-R303 PolarHBondContact O-N 3.47Å; R303-A305 PolarHBondContact O-N 2.96Å; R303-T306 WeakPolarHBondContact CA-OG1 3.28Å; R303-T306 PolarHBondContact O-N 2.68Å; R303-T306 PolarHBondContact O-OG1 3.49Å; R303-G307 PolarHBondContact O-N 2.96Å
304	Q	60.3	Low	61.8	Low	152 Å²	152	118.3 Å²	118.3	71%	0.71	64%	0.642	S	S	*	*	H	α-helix	trans	-65.7	-35.3	176.4	-74.5	-173.6	-10	0	0	112.9	E300 R301 G307 R308	E300-Q304 PolarHBondContact O-N 2.74Å; R301-Q304 PolarHBondContact O-N 3.28Å; Q304-G307 PolarHBondContact O-N 3.5Å; Q304-R308 PolarHBondContact O-N 2.93Å; Q304-R308 VanDerWaalsContact O-N 3.14Å
305	A	59.4	Low	59.6	Low	64 Å²	64	120.1 Å²	120.1	53%	0.529	65%	0.654	S	S	.	*	H	α-helix	trans	-62.9	-49.9	172.7	0	0	0	0	0	111.2	R301 G302 R303 G307 R308 A309	R301-A305 PolarHBondContact O-N 3.12Å; G302-A305 PolarHBondContact O-N 2.95Å; R303-A305 PolarHBondContact O-N 2.96Å; A305-G307 VanDerWaalsContact C-N 3.26Å; A305-G307 PolarHBondContact O-N 3.14Å; A305-R308 PolarHBondContact O-N 3.22Å; A305-R308 VanDerWaalsContact O-N 3.08Å; A305-A309 PolarHBondContact O-N 3Å; A305-A309 VanDerWaalsContact O-N 3.14Å
306	T	56.5	Low	57.6	Low	106 Å²	106	126.1 Å²	126.1	65%	0.65	68%	0.677	S	S	*	*	H	α-helix	trans	-62.5	-31.4	175.3	52.9	0	0	0	0	113.2	G302 R303 R308	G302-T306 PolarHBondContact O-N 3.38Å; G302-T306 PolarHBondContact O-OG1 2.92Å; R303-T306 WeakPolarHBondContact CA-OG1 3.28Å; R303-T306 PolarHBondContact O-N 2.68Å; R303-T306 PolarHBondContact O-OG1 3.49Å; T306-R308 VanDerWaalsContact C-N 3.3Å; T306-R308 PolarHBondContact O-N 2.95Å
307	G	52.3	Low	55.2	Low	64 Å²	64	129.9 Å²	129.9	66%	0.66	70%	0.7	S	S	*	*	H	α-helix	trans	-75	-14.2	175.8	0	0	0	0	0	114.7	R303 Q304 A305	R303-G307 PolarHBondContact O-N 2.96Å; Q304-G307 PolarHBondContact O-N 3.5Å; A305-G307 VanDerWaalsContact C-N 3.26Å; A305-G307 PolarHBondContact O-N 3.14Å
308	R	47.8	Very low	53.3	Low	233 Å²	233	129.9 Å²	129.9	88%	0.879	71%	0.711	S	S	*	*	H	α-helix	trans	-104.1	-18.3	178.8	-150.9	170.8	-169	167.3	2.6	113.3	Q304 A305 T306 G310	Q304-R308 PolarHBondContact O-N 2.93Å; Q304-R308 VanDerWaalsContact O-N 3.14Å; A305-R308 PolarHBondContact O-N 3.22Å; A305-R308 VanDerWaalsContact O-N 3.08Å; T306-R308 VanDerWaalsContact C-N 3.3Å; T306-R308 PolarHBondContact O-N 2.95Å; R308-G310 PolarHBondContact O-N 3.33Å
309	A	47.3	Very low	50.9	Low	81 Å²	81	131.7 Å²	131.7	67%	0.669	73%	0.725	S	S	*	*			trans	-76.7	36.3	167.7	0	0	0	0	0	113	A305 G311	A305-A309 PolarHBondContact O-N 3Å; A305-A309 VanDerWaalsContact O-N 3.14Å; A309-G311 PolarHBondContact O-N 2.9Å
310	G	44.9	Very low	49.1	Very low	79 Å²	79	128.4 Å²	128.4	81%	0.814	73%	0.73	S	S	*	*			trans	-79.9	44.1	-175.7	0	0	0	0	0	114.5	R308	R308-G310 PolarHBondContact O-N 3.33Å
311	G	45.2	Very low	47	Very low	76 Å²	76	131.3 Å²	131.3	78%	0.784	74%	0.743	S	S	*	*	S	Bend	trans	161.6	102.7	178.6	0	0	0	0	0	113.5	A309	A309-G311 PolarHBondContact O-N 2.9Å
312	G	38.6	Very low	44.9	Very low	75 Å²	75	130.1 Å²	130.1	77%	0.773	75%	0.75	S	S	*	*			trans	155	115.1	175	0	0	0	0	0	112.9
313	Q	37.8	Very low	42.9	Very low	174 Å²	174	134 Å²	134	81%	0.813	77%	0.77	S	S	*	*			trans	17.8	123.8	163.8	-125.9	73.7	0.2	0	0	120.5	L315	Q313-L315 PolarHBondContact O-N 3.41Å
314	L	45.2	Very low	40.9	Very low	169 Å²	169	133.8 Å²	133.8	89%	0.885	78%	0.777	S	S	*	*			trans	-56.2	117.7	151.6	174.9	81.9	0	0	0	110.2
315	L	34.4	Very low	39.5	Very low	145 Å²	145	133 Å²	133	76%	0.759	78%	0.782	S	S	*	*			trans	-142.1	128.8	157.2	-106	164.5	0	0	0	108.9	Q313	Q313-L315 PolarHBondContact O-N 3.41Å
316	K	40.2	Very low	37.8	Very low	184 Å²	184	133.3 Å²	133.3	80%	0.8	79%	0.792	S	S	*	*			trans	-81.8	140.5	160.3	-80.5	176.5	168.5	-179.7	0	107
317	D	29.7	Very low	36.4	Very low	156 Å²	156	135.7 Å²	135.7	83%	0.834	80%	0.795	S	S	*	*			trans	-140.8	145.7	136.3	-86.9	-49.9	0	0	0	108.9
318	N	39.3	Very low	35	Very low	154 Å²	154	140.2 Å²	140.2	82%	0.824	80%	0.799	S	S	*	*			trans	-93.3	135.2	161.2	-60.1	-41.4	0	0	0	105.9
319	D	29.7	Very low	33.9	Very low	169 Å²	169	137.3 Å²	137.3	90%	0.904	79%	0.789	S	S	*	*			trans	-155.7	166.6	142.1	-118.8	-36.9	0	0	0	112.4
320	A	39.3	Very low	32.9	Very low	78 Å²	78	140 Å²	140	65%	0.645	79%	0.792	S	S	*	*			trans	-77	167.6	-170.7	0	0	0	0	0	114.1
321	H	30.3	Very low	32	Very low	187 Å²	187	145.3 Å²	145.3	87%	0.866	79%	0.789	S	S	*	*			trans	-131.9	113.8	160.9	-103	34.7	0	0	0	109.9
322	D	29.2	Very low	31.2	Very low	155 Å²	155	148 Å²	148	83%	0.829	79%	0.791	S	S	*	*			trans	-70.8	155.8	160.6	-74.5	-55.5	0	0	0	110.7
323	C	25.9	Very low	30.7	Very low	121 Å²	121	149.5 Å²	149.5	82%	0.818	79%	0.786	S	S	*	*			trans	-142	83.9	173.9	-82.6	0	0	0	0	111.1
324	E	26.3	Very low	30.2	Very low	188 Å²	188	146.4 Å²	146.4	88%	0.879	78%	0.784	S	S	*	*			trans	-88.9	118.9	154.9	-71.8	-167.4	120.3	0	0	107.7
325	V	30.4	Very low	29.4	Very low	135 Å²	135	144.7 Å²	144.7	82%	0.818	78%	0.78	S	S	*	*				86.1	135.1	73.1	168.1	0	0	0	0	112.8
326	G	24.2	Very low	29.1	Very low	70 Å²	70	144.8 Å²	144.8	72%	0.722	78%	0.78	S	S	*	*			trans	137.8	67.4	-173.7	0	0	0	0	0	111.8
327	E	25.8	Very low	28.4	Very low	156 Å²	156	145.2 Å²	145.2	73%	0.729	79%	0.785	S	S	*	*				66.6	112	85.9	-66.6	-139	127.6	0	0	116
328	H	23.6	Very low	28.2	Very low	159 Å²	159	148.3 Å²	148.3	74%	0.736	79%	0.786	S	S	*	*				-169.1	125.2	110.1	-123.8	-105.1	0	0	0	114.1
329	Y	25.4	Very low	27.7	Very low	172 Å²	172	146.5 Å²	146.5	68%	0.675	79%	0.786	S	S	*	*			trans	34.2	139.4	134.5	-68.3	-102.3	0	0	0	121.4
330	D	26.1	Very low	27.6	Very low	138 Å²	138	144.1 Å²	144.1	74%	0.738	78%	0.782	S	S	*	*			cis	-167.2	176.1	-2.5	-154	-8.6	0	0	0	112.7
331	Y	24.6	Very low	26.9	Very low	190 Å²	190	145.6 Å²	145.6	75%	0.745	79%	0.787	S	S	*	*			trans	77.4	103.9	154.1	-148.5	-93.3	0	0	0	120.6	P333	Y331-P333 HydrophobicContact CE1-CG 4.43Å
332	V	28.4	Very low	26.7	Very low	134 Å²	134	142.7 Å²	142.7	81%	0.812	79%	0.786	S	S	*	*			trans	-134.8	136.5	160.4	178.3	0	0	0	0	109.3
333	P	28.7	Very low	26.6	Very low	105 Å²	105	138.7 Å²	138.7	68%	0.682	78%	0.782	S	S	*	*			trans	-69.3	146.4	-177.7	-20.1	33.1	0	0	0	114.6	Y331	Y331-P333 HydrophobicContact CE1-CG 4.43Å
334	S	28.1	Very low	26.6	Very low	109 Å²	109	141.6 Å²	141.6	76%	0.762	78%	0.783	S	S	*	*			trans	-74.3	152.2	179.4	57.4	0	0	0	0	114.6
335	V	27.6	Very low	26.6	Very low	134 Å²	134	141.6 Å²	141.6	81%	0.812	78%	0.783	S	S	*	*				178.4	155.2	121.8	145.3	0	0	0	0	111.2
336	I	28.1	Very low	26.5	Very low	147 Å²	147	144.1 Å²	144.1	75%	0.754	79%	0.786	S	S	*	*			trans	79.7	110.5	-173.6	-44.5	-166.5	0	0	0	114.5
337	Q	25.9	Very low	26.5	Very low	193 Å²	193	147.1 Å²	147.1	90%	0.902	79%	0.79	S	S	*	*			trans	-107.8	127.8	-176.4	-179	179.1	6.1	0	0	108.7
338	Y	26.4	Very low	26.6	Very low	220 Å²	220	144.6 Å²	144.6	86%	0.863	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-97.1	131.8	172.3	-91	-90.2	0	0	0	110.4
339	S	27.5	Very low	26.7	Very low	116 Å²	116	141.4 Å²	141.4	81%	0.811	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-82.9	122.6	175.3	53.3	0	0	0	0	111.1
340	S	27.7	Very low	26.6	Very low	119 Å²	119	139.8 Å²	139.8	83%	0.832	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-84.1	143.1	170	-163.5	0	0	0	0	111.4
341	C	25.2	Very low	26.5	Very low	110 Å²	110	138 Å²	138	74%	0.743	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-73.9	158.6	155.4	-64	0	0	0	0	108.8
342	C	26	Very low	26.5	Very low	126 Å²	126	136.6 Å²	136.6	85%	0.851	81%	0.808	S	S	*	*			cis	-156	151.3	1.3	-132.2	0	0	0	0	110.2
343	G	26.8	Very low	26.3	Very low	71 Å²	71	135.9 Å²	135.9	73%	0.732	80%	0.804	S	S	*	*			trans	74.7	153.1	165.1	0	0	0	0	0	117.1
344	E	25.4	Very low	26	Very low	182 Å²	182	138.4 Å²	138.4	85%	0.85	81%	0.807	S	S	*	*			cis	-149.2	139.3	-14.3	-72	-171.6	84.3	0	0	109.5
345	H	26.8	Very low	25.8	Very low	187 Å²	187	139.8 Å²	139.8	87%	0.866	80%	0.801	S	S	*	*				172.7	141.5	126	-105.7	-82	0	0	0	110.6
346	Q	28.1	Very low	25.7	Very low	188 Å²	188	141.4 Å²	141.4	88%	0.879	80%	0.8	S	S	*	*			trans	-120.6	127.4	-175.6	-171.1	176.8	24.8	0	0	110.3
347	T	25.1	Very low	25.6	Very low	134 Å²	134	142.3 Å²	142.3	82%	0.822	81%	0.805	S	S	*	*			trans	-154.5	151.5	173	10.3	0	0	0	0	111.3
348	A	26.9	Very low	26.3	Very low	102 Å²	102	138.2 Å²	138.2	84%	0.843	80%	0.795	S	S	*	*			trans	67.8	135.3	-178.1	0	0	0	0	0	116.7
349	A	26.5	Very low	26.1	Very low	93 Å²	93	136.2 Å²	136.2	77%	0.769	80%	0.799	S	S	*	*				180	133.1	-66.9	0	0	0	0	0	109.9
350	T	23.5	Very low	26	Very low	137 Å²	137	134.1 Å²	134.1	84%	0.84	80%	0.796	S	S	*	*			trans	-161.4	129.7	155.6	6.9	0	0	0	0	111.4
351	S	23.4	Very low	25.8	Very low	102 Å²	102	133.3 Å²	133.3	71%	0.713	79%	0.791	S	S	*	*			trans	41.7	123.4	151.2	57	0	0	0	0	120.1
352	L	23.9	Very low	25.7	Very low	159 Å²	159	135.2 Å²	135.2	83%	0.832	79%	0.793	S	S	*	*			cis	-150.4	-166.8	3.8	-78.7	136.9	0	0	0	106.8
353	T	23.8	Very low	25.7	Very low	119 Å²	119	138.1 Å²	138.1	73%	0.73	79%	0.792	S	S	*	*			cis	-158.8	148.6	11.8	-24.9	0	0	0	0	111.1
354	Q	23.4	Very low	25.8	Very low	158 Å²	158	146.1 Å²	146.1	74%	0.738	80%	0.8	S	S	*	*			trans	39.5	112.6	145.7	-169.1	155.2	5.7	0	0	122.8
355	E	24.5	Very low	25.8	Very low	138 Å²	138	146 Å²	146	65%	0.645	80%	0.799	S	S	*	*			trans	86.3	145.3	137.9	-95	-175.8	88.7	0	0	126.2
356	Q	25	Very low	25.7	Very low	169 Å²	169	142 Å²	142	79%	0.79	79%	0.792	S	S	*	*			trans	85.3	169.6	153.2	-73.3	174.2	32.9	0	0	120.9
357	I	26.8	Very low	25.6	Very low	165 Å²	165	139.5 Å²	139.5	85%	0.846	79%	0.794	S	S	*	*			trans	-128.1	156.5	-134.8	-90.8	172.6	0	0	0	111.6
358	P	39.1	Very low	26	Very low	108 Å²	108	136.8 Å²	136.8	70%	0.701	79%	0.786	S	S	*	*			trans	-104.6	170.1	-147.5	39.9	-36	0	0	0	116.1
359	N	23.1	Very low	26.1	Very low	177 Å²	177	141.5 Å²	141.5	95%	0.947	79%	0.787	S	S	*	*			trans	-171	157.9	153	-100.4	-37.4	0	0	0	110.6
360	G	24.4	Very low	26.3	Very low	73 Å²	73	142.6 Å²	142.6	75%	0.753	79%	0.789	S	S	*	*			trans	139.6	88.9	163.8	0	0	0	0	0	117.8
361	S	23.6	Very low	26.4	Very low	102 Å²	102	142.4 Å²	142.4	71%	0.713	79%	0.787	S	S	*	*			trans	-29	153.3	158.2	51.1	0	0	0	0	120.7
362	D	24.6	Very low	26.6	Very low	150 Å²	150	148.3 Å²	148.3	80%	0.802	79%	0.794	S	S	*	*			trans	59.5	129.4	147.1	-55.8	-32.8	0	0	0	119.3
363	F	25	Very low	26.8	Very low	186 Å²	186	146.9 Å²	146.9	82%	0.816	80%	0.796	S	S	*	*				-155.6	165.7	64.2	-151.7	-105.1	0	0	0	113.4
364	R	28.4	Very low	26.9	Very low	239 Å²	239	146.4 Å²	146.4	90%	0.902	80%	0.797	S	S	*	*			trans	-125.8	113.7	-179.2	177.6	-166.1	-174.6	-166.8	4.5	110.4
365	E	26.5	Very low	27.7	Very low	180 Å²	180	147 Å²	147	84%	0.841	81%	0.805	S	S	*	*			trans	-140.5	159	169.4	-161.4	153.4	-149.5	0	0	112.9
366	S	25.1	Very low	28.1	Very low	103 Å²	103	147.4 Å²	147.4	72%	0.72	81%	0.811	S	S	*	*			trans	-109.3	121.4	-157.3	-175.7	0	0	0	0	113.3	A368	S366-A368 PolarHBondContact O-N 3.17Å
367	C	24.7	Very low	28.3	Very low	136 Å²	136	148.9 Å²	148.9	92%	0.919	81%	0.811	S	S	*	*			trans	-90.6	79	173.4	-164.3	0	0	0	0	111.5
368	A	33.3	Very low	28.7	Very low	77 Å²	77	145.2 Å²	145.2	64%	0.636	81%	0.805	S	S	*	*			trans	-118.9	89.4	173.2	0	0	0	0	0	111.1	S366	S366-A368 PolarHBondContact O-N 3.17Å
369	K	29.2	Very low	28.7	Very low	201 Å²	201	145.2 Å²	145.2	87%	0.874	81%	0.805	S	S	*	*			trans	-160.4	133.8	159.9	-106.8	140.4	-169.3	172.4	0	112.7
370	S	30.1	Very low	29.4	Very low	115 Å²	115	141.6 Å²	141.6	80%	0.804	79%	0.791	S	S	*	*			trans	-62.8	140.5	173.2	176.3	0	0	0	0	111.5
371	V	27.4	Very low	30.2	Very low	134 Å²	134	143.9 Å²	143.9	81%	0.812	79%	0.793	S	S	*	*			trans	-116.2	121.5	161.5	179	0	0	0	0	108.6
372	R	27.9	Very low	31	Very low	226 Å²	226	147.8 Å²	147.8	85%	0.853	80%	0.8	S	S	*	*			trans	-73.3	122.4	177.5	176.8	177.7	-69.1	157	-2	109.3	S374	R372-S374 PolarHBondContact O-N 3.43Å
373	C	27.7	Very low	31.3	Very low	128 Å²	128	149.2 Å²	149.2	87%	0.865	80%	0.801	S	S	*	*			trans	-58.9	112.1	177.3	-63.7	0	0	0	0	110.6
374	S	25.7	Very low	32	Very low	109 Å²	109	146.7 Å²	146.7	76%	0.762	80%	0.801	S	S	*	*			trans	-82.8	119.2	174.9	-163.9	0	0	0	0	109.2	R372 D376	R372-S374 PolarHBondContact O-N 3.43Å; S374-D376 VanDerWaalsContact C-N 3.35Å; S374-D376 PolarHBondContact O-N 3Å
375	L	38.8	Very low	32.3	Very low	172 Å²	172	140.9 Å²	140.9	90%	0.901	79%	0.792	S	S	*	*			trans	-79.3	82.3	175.2	-177.6	106	0	0	0	109.6
376	D	33.8	Very low	33.1	Very low	146 Å²	146	137.5 Å²	137.5	78%	0.781	79%	0.786	S	S	*	*			trans	-151.8	155.5	169.7	-124.1	-40.1	0	0	0	113.5	S374	S374-D376 VanDerWaalsContact C-N 3.35Å; S374-D376 PolarHBondContact O-N 3Å
377	Y	29.3	Very low	34.2	Very low	200 Å²	200	136.6 Å²	136.6	78%	0.784	78%	0.777	S	S	*	*			trans	59.6	72	177.6	-125.6	-84.9	0	0	0	117.9
378	A	35.5	Very low	35.3	Very low	88 Å²	88	136 Å²	136	73%	0.727	77%	0.772	S	S	*	*	P	Polyproline II helix	trans	-62	133.6	151.7	0	0	0	0	0	109.5
379	P	38.1	Very low	36	Very low	108 Å²	108	135.5 Å²	135.5	70%	0.701	76%	0.764	S	S	*	*	P	Polyproline II helix	trans	-63	146.9	178.2	26.6	-34.2	0	0	0	110.7
380	P	38.7	Very low	37.3	Very low	100 Å²	100	128.6 Å²	128.6	65%	0.649	74%	0.736	S	S	*	*	P	Polyproline II helix	trans	-59.4	135.9	-179.9	25.4	-34.2	0	0	0	109.8	H382	P380-H382 PolarHBondContact O-N 2.95Å; P380-H382 VanDerWaalsContact O-N 3.16Å
381	P	41	Very low	38.7	Very low	121 Å²	121	126.3 Å²	126.3	79%	0.786	72%	0.717	S	S	*	*	P	Polyproline II helix	trans	-59.6	125.1	-176.8	24	-33.5	0	0	0	109.7	Q383	P381-Q383 PolarHBondContact O-N 3.46Å; P381-Q383 VanDerWaalsContact O-N 3.09Å
382	H	40.6	Very low	40.1	Very low	185 Å²	185	129.4 Å²	129.4	86%	0.856	72%	0.72	S	S	*	*	P	Polyproline II helix	trans	-49.4	122.5	173.2	-88	-74.3	0	0	0	108.9	P380 V384	P380-H382 PolarHBondContact O-N 2.95Å; P380-H382 VanDerWaalsContact O-N 3.16Å; H382-V384 PolarHBondContact O-N 2.03Å
383	Q	29.9	Very low	41.5	Very low	180 Å²	180	121.6 Å²	121.6	84%	0.841	70%	0.703	S	S	*	*			trans	-62.9	102.6	-179.9	-68.1	-175	7.7	0	0	108.8	P381 T385	P381-Q383 PolarHBondContact O-N 3.46Å; P381-Q383 VanDerWaalsContact O-N 3.09Å; Q383-T385 VanDerWaalsContact C-N 3.28Å; Q383-T385 PolarHBondContact O-N 2.92Å
384	V	39.4	Very low	43.4	Very low	132 Å²	132	119 Å²	119	80%	0.8	68%	0.68	S	S	*	*			trans	-60.9	98.1	165.4	178.3	0	0	0	0	106	H382 P386	H382-V384 PolarHBondContact O-N 2.03Å; V384-P386 WeakPolarHBondContact O-CD 3.05Å
385	T	36.5	Very low	45.2	Very low	118 Å²	118	117.2 Å²	117.2	72%	0.724	67%	0.667	S	S	*	*	P	Polyproline II helix	trans	-54.9	117.3	178.4	45	0	0	0	0	107.6	Q383	Q383-T385 VanDerWaalsContact C-N 3.28Å; Q383-T385 PolarHBondContact O-N 2.92Å
386	P	43.3	Very low	46.7	Very low	108 Å²	108	111.4 Å²	111.4	70%	0.701	64%	0.635	S	S	*	*	P	Polyproline II helix	trans	-60.4	136.1	-171.5	22.2	-32.6	0	0	0	109.1	V384	V384-P386 WeakPolarHBondContact O-CD 3.05Å
387	P	47.6	Very low	48.4	Very low	84 Å²	84	105.6 Å²	105.6	55%	0.545	60%	0.604	S	S	.	*	P	Polyproline II helix	trans	-53.9	139.6	179.2	23.7	-34	0	0	0	109	S389	P387-S389 PolarHBondContact O-N 2.88Å
388	P	47.6	Very low	50.4	Low	124 Å²	124	96.8 Å²	96.8	81%	0.805	57%	0.571	S	S	*	*			trans	-53.1	105.6	-160.7	19.5	-33.2	0	0	0	110.5	I390	P388-I390 PolarHBondContact O-N 2.92Å
389	S	47.4	Very low	52.4	Low	67 Å²	67	99.6 Å²	99.6	47%	0.469	56%	0.563	S	S	.	*			trans	-60	141.6	-176.3	70.1	0	0	0	0	109.1	P387 T391	P387-S389 PolarHBondContact O-N 2.88Å; S389-T391 PolarHBondContact O-N 3.06Å; S389-T391 WeakPolarHBondContact OG-CG2 3.49Å
390	I	56.9	Low	54.3	Low	56 Å²	56	94.5 Å²	94.5	29%	0.287	53%	0.53	S	S	.	.			trans	-62.5	88.7	160.5	-64.3	171.1	0	0	0	105.9	I263 N266 I267 P388 M394	I263-I390 HydrophobicContact CG2-CD1 4.35Å; N266-I390 HydrophobicContact CB-CD1 4.01Å; I267-I390 HydrophobicContact CD1-CD1 4.31Å; I267-I390 HydrophobicContact CG1-CD1 3.56Å; P388-I390 PolarHBondContact O-N 2.92Å; I390-M394 HydrophobicContact CG2-CB 4.02Å
391	T	60.5	Low	56.3	Low	67 Å²	67	89.8 Å²	89.8	41%	0.411	50%	0.499	S	S	.	.			trans	-64	155.5	178.6	45.2	0	0	0	0	108.6	S389 A393 M394 S395	S389-T391 PolarHBondContact O-N 3.06Å; S389-T391 WeakPolarHBondContact OG-CG2 3.49Å; T391-A393 PolarHBondContact O-N 3.36Å; T391-M394 WeakPolarHBondContact O-CB 3.48Å; T391-M394 PolarHBondContact O-N 3.36Å; T391-S395 PolarHBondContact O-N 3.1Å
392	K	56.9	Low	58.3	Low	198 Å²	198	87.9 Å²	87.9	86%	0.861	48%	0.482	S	S	*	.	H	α-helix	trans	-54.6	-25.4	174.1	-62.4	-179.1	-180	179.7	0	111.6	K396	K392-K396 WeakPolarHBondContact O-CB 3.29Å; K392-K396 PolarHBondContact O-N 3.09Å
393	A	57.3	Low	60.4	Low	62 Å²	62	81.3 Å²	81.3	51%	0.512	46%	0.455	S	S	.	.	H	α-helix	trans	-64	-46.4	170.3	0	0	0	0	0	114.3	T391 K396 T397	T391-A393 PolarHBondContact O-N 3.36Å; A393-K396 PolarHBondContact O-N 2.95Å; A393-T397 WeakPolarHBondContact O-CB 3.37Å; A393-T397 PolarHBondContact O-N 2.86Å; A393-T397 PolarHBondContact O-OG1 3.05Å
394	M	65.7	Low	63	Low	74 Å²	74	73 Å²	73	37%	0.365	42%	0.416	S	S	.	.	H	α-helix	trans	-58.7	-51.3	177	-73.2	-66.1	-159.4	0	0	111	I174 I390 T391 K396 T397 V398	I174-M394 HydrophobicContact CG1-SD 4.04Å; I390-M394 HydrophobicContact CG2-CB 4.02Å; T391-M394 WeakPolarHBondContact O-CB 3.48Å; T391-M394 PolarHBondContact O-N 3.36Å; M394-K396 PolarHBondContact O-N 3.09Å; M394-T397 WeakPolarHBondContact O-CB 3.37Å; M394-T397 PolarHBondContact O-N 3.12Å; M394-T397 VanDerWaalsContact O-N 3.15Å; M394-V398 VanDerWaalsContact O-CG2 3.23Å; M394-V398 WeakPolarHBondContact O-CG2 3.35Å; M394-V398 PolarHBondContact O-N 2.93Å
395	S	65.4	Low	65.1	Low	71 Å²	71	67.7 Å²	67.7	50%	0.497	38%	0.384	S	S	.	.	H	α-helix	trans	-60.5	-42.2	177.8	177.5	0	0	0	0	112.4	T391 T397 V398 R399	T391-S395 PolarHBondContact O-N 3.1Å; S395-T397 VanDerWaalsContact C-N 3.31Å; S395-T397 PolarHBondContact O-N 3.47Å; S395-V398 PolarHBondContact O-N 2.85Å; S395-R399 WeakPolarHBondContact O-CB 3.42Å; S395-R399 PolarHBondContact O-N 3.26Å
396	K	70.3	Confident	67.6	Low	51 Å²	51	67.6 Å²	67.6	22%	0.222	38%	0.378	C	S	.	.	H	α-helix	trans	-60.9	-40.1	175.4	-161.1	-177.6	-165.5	-146.4	0	112	K392 A393 M394 M400 A455 F456	K392-K396 WeakPolarHBondContact O-CB 3.29Å; K392-K396 PolarHBondContact O-N 3.09Å; A393-K396 PolarHBondContact O-N 2.95Å; M394-K396 PolarHBondContact O-N 3.09Å; K396-M400 PolarHBondContact O-N 3.3Å; K396-A455 WeakPolarHBondContact CE-O 3.19Å; K396-A455 PolarHBondContact NZ-O 2.88Å; K396-F456 VanDerWaalsContact CD-O 3.23Å; K396-F456 WeakPolarHBondContact CD-O 3.25Å; K396-F456 WeakPolarHBondContact CE-O 3.33Å; K396-F456 HydrophobicContact CG-CD1 4.48Å; K396-F456 VanDerWaalsContact NZ-C 3.26Å; K396-F456 PolarHBondContact NZ-O 3.14Å
397	T	68.3	Low	69.7	Low	24 Å²	24	63.7 Å²	63.7	15%	0.147	35%	0.352	C	S	.	.	H	α-helix	trans	-68.3	-36.8	179.4	-58.4	0	0	0	0	112.4	R170 A393 M394 S395 M400 T401	R170-T397 HydrophobicContact CG-CG2 4.2Å; A393-T397 WeakPolarHBondContact O-CB 3.37Å; A393-T397 PolarHBondContact O-N 2.86Å; A393-T397 PolarHBondContact O-OG1 3.05Å; M394-T397 WeakPolarHBondContact O-CB 3.37Å; M394-T397 PolarHBondContact O-N 3.12Å; M394-T397 VanDerWaalsContact O-N 3.15Å; S395-T397 VanDerWaalsContact C-N 3.31Å; S395-T397 PolarHBondContact O-N 3.47Å; T397-M400 VanDerWaalsContact O-CB 3.29Å; T397-M400 WeakPolarHBondContact O-CB 3.33Å; T397-M400 PolarHBondContact O-N 3.45Å; T397-T401 PolarHBondContact O-N 3.37Å
398	V	71.3	Confident	71.8	Confident	15 Å²	15	59.7 Å²	59.7	9%	0.091	33%	0.326	C	S	.	.	H	α-helix	trans	-75.1	-39.8	179.8	174.1	0	0	0	0	111	I174 I259 I263 M394 S395 M400 T401 L402	I174-V398 HydrophobicContact CD1-CG2 3.72Å; I259-V398 HydrophobicContact CG2-CG1 4.1Å; I259-V398 HydrophobicContact CG2-CG2 3.97Å; I263-V398 HydrophobicContact CD1-CB 4.07Å; I263-V398 HydrophobicContact CD1-CG1 3.8Å; I263-V398 HydrophobicContact CD1-CG2 3.25Å; M394-V398 VanDerWaalsContact O-CG2 3.23Å; M394-V398 WeakPolarHBondContact O-CG2 3.35Å; M394-V398 PolarHBondContact O-N 2.93Å; S395-V398 PolarHBondContact O-N 2.85Å; V398-M400 PolarHBondContact O-N 2.73Å; V398-T401 PolarHBondContact O-N 2.78Å; V398-T401 PolarHBondContact O-OG1 3.36Å; V398-T401 VanDerWaalsContact O-OG1 3.06Å; V398-L402 HydrophobicContact CG1-CD1 4.38Å; V398-L402 WeakPolarHBondContact O-CG 3.31Å; V398-L402 PolarHBondContact O-N 3.13Å
399	R	78.7	Confident	73.7	Confident	146 Å²	146	56.2 Å²	56.2	55%	0.551	30%	0.303	S	S	*	.	H	α-helix	trans	-61.8	-32.8	171	-166.1	172.6	62	159.9	11.4	111.7	S395 V403 F456	S395-R399 WeakPolarHBondContact O-CB 3.42Å; S395-R399 PolarHBondContact O-N 3.26Å; R399-V403 WeakPolarHBondContact O-CG2 3.36Å; R399-V403 PolarHBondContact O-N 3.05Å; R399-F456 HydrophobicContact CB-CE1 4.23Å; R399-F456 HydrophobicContact CG-CE1 3.87Å; R399-F456 HydrophobicContact CG-CZ 4.48Å
400	M	77.4	Confident	75.7	Confident	1 Å²	1	57.3 Å²	57.3	1%	0.005	31%	0.307	C	S	.	.	H	α-helix	trans	-65.8	-49.8	172.7	-171.2	-179.4	-175.2	0	0	112.4	M107 M111 M166 K396 T397 V398 L402 V403 I404 I452 Y453 F456	M107-M400 HydrophobicContact CE-CE 4.1Å; M107-M400 HydrophobicContact CE-SD 3.41Å; M107-M400 WeakPolarHBondContact CE-SD 3.45Å; M111-M400 HydrophobicContact CE-CE 4.46Å; M166-M400 HydrophobicContact CE-CE 3.89Å; M166-M400 HydrophobicContact CE-SD 4.03Å; K396-M400 PolarHBondContact O-N 3.3Å; T397-M400 VanDerWaalsContact O-CB 3.29Å; T397-M400 WeakPolarHBondContact O-CB 3.33Å; T397-M400 PolarHBondContact O-N 3.45Å; V398-M400 PolarHBondContact O-N 2.73Å; M400-L402 VanDerWaalsContact C-N 3.34Å; M400-L402 PolarHBondContact O-N 3.21Å; M400-V403 PolarHBondContact O-N 3.16Å; M400-I404 HydrophobicContact CE-CD1 4.39Å; M400-I404 HydrophobicContact CG-CD1 4.04Å; M400-I404 WeakPolarHBondContact O-CG1 3.25Å; M400-I404 PolarHBondContact O-N 2.97Å; M400-I452 HydrophobicContact CE-CG2 3.96Å; M400-I452 HydrophobicContact CG-CG2 4.04Å; M400-Y453 HydrophobicContact CE-CD1 3.5Å; M400-Y453 HydrophobicContact CE-CE1 3.74Å; M400-F456 HydrophobicContact CB-CB 3.59Å; M400-F456 HydrophobicContact CB-CD1 4Å; M400-F456 HydrophobicContact CB-CD2 4.29Å; M400-F456 HydrophobicContact CB-CG 3.68Å; M400-F456 HydrophobicContact CE-CB 4.23Å; M400-F456 HydrophobicContact CG-CB 3.39Å; M400-F456 HydrophobicContact CG-CD2 4.08Å; M400-F456 HydrophobicContact CG-CG 3.77Å; M400-F456 HydrophobicContact SD-CB 3.61Å
401	T	80.4	Confident	77.2	Confident	1 Å²	1	55.1 Å²	55.1	1%	0.006	30%	0.296	C	S	.	.	H	α-helix	trans	-64.3	-39.7	-179.1	52.6	0	0	0	0	111.8	T167 R170 Q256 T397 V398 V403 I404 V405	T167-T401 HydrophobicContact CG2-CG2 4.25Å; R170-T401 HydrophobicContact CB-CG2 4.22Å; R170-T401 HydrophobicContact CG-CG2 3.82Å; Q256-T401 VanDerWaalsContact OE1-CB 3.24Å; Q256-T401 PolarHBondContact OE1-OG1 3.14Å; T397-T401 PolarHBondContact O-N 3.37Å; V398-T401 PolarHBondContact O-N 2.78Å; V398-T401 PolarHBondContact O-OG1 3.36Å; V398-T401 VanDerWaalsContact O-OG1 3.06Å; T401-V403 PolarHBondContact O-N 3.42Å; T401-I404 PolarHBondContact O-N 2.72Å; T401-V405 WeakPolarHBondContact O-CG2 3.23Å; T401-V405 PolarHBondContact O-N 3.43Å
402	L	82.8	Confident	78.6	Confident	81 Å²	81	52.2 Å²	52.2	42%	0.424	28%	0.278	S	S	.	.	H	α-helix	trans	-59.3	-43.1	173.9	-71.5	174.7	0	0	0	112.9	Q256 V398 M400 V405 L406	Q256-L402 HydrophobicContact CB-CD2 4.34Å; Q256-L402 HydrophobicContact CG-CD2 4.27Å; V398-L402 HydrophobicContact CG1-CD1 4.38Å; V398-L402 WeakPolarHBondContact O-CG 3.31Å; V398-L402 PolarHBondContact O-N 3.13Å; M400-L402 VanDerWaalsContact C-N 3.34Å; M400-L402 PolarHBondContact O-N 3.21Å; L402-V405 PolarHBondContact O-N 3.06Å; L402-L406 PolarHBondContact O-N 3.13Å; L402-L406 VanDerWaalsContact O-N 3.1Å
403	V	85.6	Confident	80.2	Confident	47 Å²	47	44.3 Å²	44.3	29%	0.285	25%	0.248	S	C	.	.	H	α-helix	trans	-64.7	-40.6	175.1	168	0	0	0	0	111.5	R399 M400 T401 V405 L406 V407 I452 F456	R399-V403 WeakPolarHBondContact O-CG2 3.36Å; R399-V403 PolarHBondContact O-N 3.05Å; M400-V403 PolarHBondContact O-N 3.16Å; T401-V403 PolarHBondContact O-N 3.42Å; V403-V405 VanDerWaalsContact C-N 3.33Å; V403-V405 PolarHBondContact O-N 2.85Å; V403-L406 PolarHBondContact O-N 3.36Å; V403-V407 HydrophobicContact CG1-CG2 4.11Å; V403-V407 WeakPolarHBondContact O-CB 3.16Å; V403-V407 WeakPolarHBondContact O-CG2 3.19Å; V403-V407 PolarHBondContact O-N 3.01Å; V403-I452 HydrophobicContact CG1-CD1 4.41Å; V403-I452 HydrophobicContact CG1-CG1 4.21Å; V403-F456 HydrophobicContact CB-CE2 4.09Å; V403-F456 HydrophobicContact CB-CZ 4.34Å; V403-F456 HydrophobicContact CG1-CE2 4.04Å; V403-F456 HydrophobicContact CG2-CE2 4.03Å; V403-F456 HydrophobicContact CG2-CZ 3.81Å
404	I	82.9	Confident	81.6	Confident	7 Å²	7	42.6 Å²	42.6	4%	0.036	23%	0.231	C	C	.	.	H	α-helix	trans	-59.4	-44.3	175.3	-66.6	163.4	0	0	0	110.6	I163 M166 M400 T401 L406 Y408 I452	I163-I404 HydrophobicContact CD1-CG2 4.33Å; I163-I404 HydrophobicContact CG1-CG2 4.24Å; I163-I404 HydrophobicContact CG2-CG2 3.5Å; I163-I404 VanDerWaalsContact CG2-CG2 3.5Å; M166-I404 HydrophobicContact CE-CD1 3.88Å; M166-I404 HydrophobicContact SD-CD1 4.23Å; M400-I404 HydrophobicContact CE-CD1 4.39Å; M400-I404 HydrophobicContact CG-CD1 4.04Å; M400-I404 WeakPolarHBondContact O-CG1 3.25Å; M400-I404 PolarHBondContact O-N 2.97Å; T401-I404 PolarHBondContact O-N 2.72Å; I404-L406 PolarHBondContact O-N 3.31Å; I404-Y408 WeakPolarHBondContact O-CB 3.5Å; I404-Y408 PolarHBondContact O-N 3.23Å; I404-I452 HydrophobicContact CD1-CG2 4.18Å; I404-I452 HydrophobicContact CG1-CD1 4.07Å; I404-I452 HydrophobicContact CG1-CG2 3.77Å
405	V	84.4	Confident	82.5	Confident	20 Å²	20	39.3 Å²	39.3	12%	0.121	22%	0.215	C	C	.	.	H	α-helix	trans	-61	-45.9	177.4	-170.9	0	0	0	0	111.8	I252 Q256 T401 L402 V403 T409	I252-V405 HydrophobicContact CG2-CB 4.01Å; I252-V405 HydrophobicContact CG2-CG1 3.79Å; I252-V405 HydrophobicContact CG2-CG2 3.26Å; Q256-V405 HydrophobicContact CG-CG2 3.44Å; Q256-V405 VanDerWaalsContact CG-CG2 3.44Å; T401-V405 WeakPolarHBondContact O-CG2 3.23Å; T401-V405 PolarHBondContact O-N 3.43Å; L402-V405 PolarHBondContact O-N 3.06Å; V403-V405 VanDerWaalsContact C-N 3.33Å; V403-V405 PolarHBondContact O-N 2.85Å; V405-T409 VanDerWaalsContact O-CB 3.32Å; V405-T409 WeakPolarHBondContact O-CB 3.11Å; V405-T409 PolarHBondContact O-N 2.81Å; V405-T409 PolarHBondContact O-OG1 2.97Å
406	L	87.9	Confident	83.4	Confident	115 Å²	115	36.3 Å²	36.3	60%	0.602	19%	0.193	S	C	*	.	H	α-helix	trans	-65.1	-48.7	-177.9	-176.5	149.8	0	0	0	111.2	L402 V403 I404 T409 V410	L402-L406 PolarHBondContact O-N 3.13Å; L402-L406 VanDerWaalsContact O-N 3.1Å; V403-L406 PolarHBondContact O-N 3.36Å; I404-L406 PolarHBondContact O-N 3.31Å; L406-T409 PolarHBondContact O-N 2.81Å; L406-V410 HydrophobicContact CD2-CG2 4.37Å; L406-V410 WeakPolarHBondContact O-CB 3.33Å; L406-V410 VanDerWaalsContact O-CG2 3.28Å; L406-V410 WeakPolarHBondContact O-CG2 3.49Å; L406-V410 PolarHBondContact O-N 2.82Å
407	V	89.4	Confident	84.2	Confident	26 Å²	26	38.7 Å²	38.7	16%	0.158	21%	0.207	C	C	.	.	H	α-helix	trans	-59.3	-51.2	177.5	168.1	0	0	0	0	110.6	V403 T409 V410 C411 T448 I452	V403-V407 HydrophobicContact CG1-CG2 4.11Å; V403-V407 WeakPolarHBondContact O-CB 3.16Å; V403-V407 WeakPolarHBondContact O-CG2 3.19Å; V403-V407 PolarHBondContact O-N 3.01Å; V407-T409 VanDerWaalsContact C-N 3.34Å; V407-T409 PolarHBondContact O-N 2.82Å; V407-V410 PolarHBondContact O-N 3.32Å; V407-C411 WeakPolarHBondContact O-CB 3.43Å; V407-C411 PolarHBondContact O-N 3.44Å; V407-C411 PolarHBondContact O-SG 3.45Å; V407-C411 VanDerWaalsContact O-SG 3.35Å; V407-T448 HydrophobicContact CG1-CG2 4.4Å; V407-T448 WeakPolarHBondContact CG1-OG1 3.44Å; V407-I452 HydrophobicContact CB-CD1 4.41Å; V407-I452 HydrophobicContact CG1-CD1 4.36Å; V407-I452 HydrophobicContact CG2-CD1 4.31Å
408	Y	89.8	Confident	84.8	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-54.5	-48.7	177.3	179	-90.9	0	0	0	111.9	S160 I163 V244 F245 P248 A249 I252 I404 V410 C411 W412	S160-Y408 PolarHBondContact OG-OH 2.92Å; I163-Y408 HydrophobicContact CD1-CD2 3.83Å; I163-Y408 HydrophobicContact CD1-CE2 4.39Å; V244-Y408 PolarHBondContact O-OH 3.45Å; F245-Y408 HydrophobicContact CD2-CE1 4.09Å; P248-Y408 WeakPolarHBondContact CB-OH 3.36Å; A249-Y408 HydrophobicContact CB-CE1 4.33Å; I252-Y408 HydrophobicContact CD1-CD1 4.5Å; I252-Y408 HydrophobicContact CD1-CE1 4.43Å; I404-Y408 WeakPolarHBondContact O-CB 3.5Å; I404-Y408 PolarHBondContact O-N 3.23Å; Y408-V410 PolarHBondContact O-N 3.16Å; Y408-C411 PolarHBondContact O-N 3.21Å; Y408-W412 AromaticContact CD2-CD1 3.31Å; Y408-W412 AromaticContact CD2-NE1 3.49Å; Y408-W412 AromaticContact CE2-CD1 3.26Å; Y408-W412 HydrophobicContact CE2-CG 4.29Å; Y408-W412 AromaticContact CE2-NE1 3.35Å; Y408-W412 VanDerWaalsContact CE2-NE1 3.35Å; Y408-W412 AromaticContact CG-CD1 3.75Å; Y408-W412 AromaticContact CZ-CD1 3.64Å; Y408-W412 WeakPolarHBondContact O-CB 3.46Å; Y408-W412 PolarHBondContact O-N 3.28Å
409	T	89.4	Confident	85.1	Confident	52 Å²	52	37.6 Å²	37.6	32%	0.319	20%	0.2	S	C	.	.	H	α-helix	trans	-66.2	-41.1	-177.7	-52.2	0	0	0	0	111.8	V405 L406 V407 S413	V405-T409 VanDerWaalsContact O-CB 3.32Å; V405-T409 WeakPolarHBondContact O-CB 3.11Å; V405-T409 PolarHBondContact O-N 2.81Å; V405-T409 PolarHBondContact O-OG1 2.97Å; L406-T409 PolarHBondContact O-N 2.81Å; V407-T409 VanDerWaalsContact C-N 3.34Å; V407-T409 PolarHBondContact O-N 2.82Å; T409-S413 WeakPolarHBondContact O-CB 3.12Å; T409-S413 PolarHBondContact O-N 3.42Å
410	V	88.9	Confident	85.3	Confident	89 Å²	89	33.5 Å²	33.5	54%	0.539	19%	0.189	S	C	.	.	H	α-helix	trans	-70.7	-34.2	179.4	171.1	0	0	0	0	112.3	L406 V407 Y408 P414	L406-V410 HydrophobicContact CD2-CG2 4.37Å; L406-V410 WeakPolarHBondContact O-CB 3.33Å; L406-V410 VanDerWaalsContact O-CG2 3.28Å; L406-V410 WeakPolarHBondContact O-CG2 3.49Å; L406-V410 PolarHBondContact O-N 2.82Å; V407-V410 PolarHBondContact O-N 3.32Å; Y408-V410 PolarHBondContact O-N 3.16Å; V410-P414 WeakPolarHBondContact O-CD 3.44Å; V410-P414 WeakPolarHBondContact O-CG 3.28Å
411	C	88.8	Confident	85.5	Confident	10 Å²	10	39.2 Å²	39.2	7%	0.068	21%	0.21	C	C	.	.	H	α-helix	trans	-75.8	-41.6	176.8	-70.5	0	0	0	0	113.1	V407 Y408 L441 A442 N445	V407-C411 WeakPolarHBondContact O-CB 3.43Å; V407-C411 PolarHBondContact O-N 3.44Å; V407-C411 PolarHBondContact O-SG 3.45Å; V407-C411 VanDerWaalsContact O-SG 3.35Å; Y408-C411 PolarHBondContact O-N 3.21Å; C411-L441 WeakPolarHBondContact CB-O 3.31Å; C411-L441 CarbonylContact O-C 3.39Å; C411-A442 WeakPolarHBondContact O-CA 3.48Å; C411-A442 PolarHBondContact O-N 3.24Å; C411-N445 HydrophobicContact CB-CB 3.86Å
412	W	88.7	Confident	85.2	Confident	6 Å²	6	40.3 Å²	40.3	2%	0.023	22%	0.22	C	C	.	.	H	α-helix	trans	-88.4	-35.5	-173.3	-72.4	112.1	0	0	0	115.1	M156 F245 Y408 F415 F416 A442 N445	M156-W412 HydrophobicContact CE-CH2 3.36Å; M156-W412 HydrophobicContact CE-CZ3 3.75Å; M156-W412 HydrophobicContact CG-CH2 3.77Å; M156-W412 HydrophobicContact CG-CZ2 4.39Å; M156-W412 HydrophobicContact CG-CZ3 4.26Å; M156-W412 HydrophobicContact SD-CH2 3.56Å; M156-W412 VanDerWaalsContact SD-CH2 3.56Å; M156-W412 HydrophobicContact SD-CZ3 3.57Å; M156-W412 VanDerWaalsContact SD-CZ3 3.57Å; F245-W412 HydrophobicContact CD2-CB 3.57Å; F245-W412 HydrophobicContact CE2-CB 3.99Å; F245-W412 HydrophobicContact CG-CB 4.31Å; Y408-W412 AromaticContact CD2-CD1 3.31Å; Y408-W412 AromaticContact CD2-NE1 3.49Å; Y408-W412 AromaticContact CE2-CD1 3.26Å; Y408-W412 HydrophobicContact CE2-CG 4.29Å; Y408-W412 AromaticContact CE2-NE1 3.35Å; Y408-W412 VanDerWaalsContact CE2-NE1 3.35Å; Y408-W412 AromaticContact CG-CD1 3.75Å; Y408-W412 AromaticContact CZ-CD1 3.64Å; Y408-W412 WeakPolarHBondContact O-CB 3.46Å; Y408-W412 PolarHBondContact O-N 3.28Å; W412-F415 HydrophobicContact CE3-CD1 4.22Å; W412-F415 HydrophobicContact CZ3-CD1 4.31Å; W412-F415 PolarHBondContact O-N 3.38Å; W412-F416 HydrophobicContact CB-CD2 4.26Å; W412-F416 HydrophobicContact CD2-CE2 4.19Å; W412-F416 HydrophobicContact CE3-CD2 4.02Å; W412-F416 AromaticContact CE3-CE2 3.42Å; W412-F416 HydrophobicContact CE3-CE2 3.42Å; W412-F416 VanDerWaalsContact CE3-CE2 3.42Å; W412-F416 HydrophobicContact CE3-CZ 4.29Å; W412-F416 HydrophobicContact CZ3-CE2 4.03Å; W412-F416 HydrophobicContact CZ3-CZ 4.49Å; W412-F416 WeakPolarHBondContact O-CD2 3.43Å; W412-F416 PolarHBondContact O-N 2.93Å; W412-F416 VanDerWaalsContact O-N 3.08Å; W412-A442 HydrophobicContact CE3-CB 3.88Å; W412-A442 HydrophobicContact CH2-CB 4.05Å; W412-A442 HydrophobicContact CZ3-CB 3.55Å; W412-N445 HydrophobicContact CZ2-CB 4.39Å
413	S	90.1	Very high	84.8	Confident	33 Å²	33	36.9 Å²	36.9	23%	0.231	20%	0.203	C	C	.	.	H	α-helix	trans	-56.9	-47.7	-175.8	-172	0	0	0	0	112.9	T409 F415 F416 I417	T409-S413 WeakPolarHBondContact O-CB 3.12Å; T409-S413 PolarHBondContact O-N 3.42Å; S413-F415 PolarHBondContact O-N 3Å; S413-F416 PolarHBondContact O-N 3.16Å; S413-I417 WeakPolarHBondContact O-CB 3.47Å; S413-I417 WeakPolarHBondContact O-CD1 3.17Å; S413-I417 WeakPolarHBondContact O-CG1 3.44Å; S413-I417 PolarHBondContact O-N 3.48Å; S413-I417 WeakPolarHBondContact OG-CD1 3.21Å
414	P	87.6	Confident	84.5	Confident	26 Å²	26	41.4 Å²	41.4	17%	0.169	22%	0.215	C	C	.	.	H	α-helix	trans	-65	-44.3	-176.5	-21.4	35.7	0	0	0	112.7	V410 F416 I417 V418 L438 L441	V410-P414 WeakPolarHBondContact O-CD 3.44Å; V410-P414 WeakPolarHBondContact O-CG 3.28Å; P414-F416 PolarHBondContact O-N 2.88Å; P414-I417 PolarHBondContact O-N 3.02Å; P414-V418 WeakPolarHBondContact O-CB 3.33Å; P414-V418 WeakPolarHBondContact O-CG2 3.44Å; P414-V418 PolarHBondContact O-N 3.38Å; P414-L438 HydrophobicContact CB-CB 4.39Å; P414-L438 HydrophobicContact CB-CD2 3.7Å; P414-L441 HydrophobicContact CB-CD1 3.89Å; P414-L441 HydrophobicContact CG-CD1 3.73Å
415	F	83.5	Confident	84.2	Confident	4 Å²	4	44.2 Å²	44.2	2%	0.018	23%	0.23	C	C	.	.	H	α-helix	trans	-56.7	-50.6	174.9	168.9	-92.3	0	0	0	111.4	F46 W412 S413 V418 Q419 M439 A442	F46-F415 HydrophobicContact CD2-CE1 4.47Å; F46-F415 AromaticContact CD2-CE2 3.89Å; F46-F415 HydrophobicContact CD2-CE2 3.89Å; F46-F415 AromaticContact CD2-CZ 3.41Å; F46-F415 HydrophobicContact CD2-CZ 3.41Å; F46-F415 VanDerWaalsContact CD2-CZ 3.41Å; F46-F415 HydrophobicContact CE2-CE1 4.47Å; F46-F415 HydrophobicContact CE2-CE2 4.37Å; F46-F415 AromaticContact CE2-CZ 3.74Å; F46-F415 HydrophobicContact CE2-CZ 3.74Å; F46-F415 HydrophobicContact CG-CZ 4.4Å; W412-F415 HydrophobicContact CE3-CD1 4.22Å; W412-F415 HydrophobicContact CZ3-CD1 4.31Å; W412-F415 PolarHBondContact O-N 3.38Å; S413-F415 PolarHBondContact O-N 3Å; F415-V418 PolarHBondContact O-N 2.8Å; F415-Q419 HydrophobicContact CD1-CG 4.43Å; F415-Q419 HydrophobicContact CD2-CG 4.22Å; F415-Q419 HydrophobicContact CE1-CG 4.12Å; F415-Q419 HydrophobicContact CE2-CG 3.9Å; F415-Q419 HydrophobicContact CG-CG 4.46Å; F415-Q419 HydrophobicContact CZ-CG 3.82Å; F415-Q419 WeakPolarHBondContact O-CB 3.37Å; F415-Q419 WeakPolarHBondContact O-CG 3.22Å; F415-Q419 PolarHBondContact O-N 2.94Å; F415-M439 HydrophobicContact CD2-CE 4.1Å; F415-M439 HydrophobicContact CD2-SD 3.57Å; F415-M439 VanDerWaalsContact CD2-SD 3.57Å; F415-M439 HydrophobicContact CE2-CE 3.7Å; F415-M439 HydrophobicContact CE2-SD 3.78Å; F415-A442 HydrophobicContact CB-CB 3.96Å; F415-A442 HydrophobicContact CD1-CB 4.46Å; F415-A442 HydrophobicContact CD2-CB 4.1Å; F415-A442 HydrophobicContact CG-CB 3.92Å
416	F	85.6	Confident	83.3	Confident	8 Å²	8	48 Å²	48	4%	0.035	26%	0.255	C	S	.	.	H	α-helix	trans	-74	-27.7	-177.5	-79.2	-63.3	0	0	0	114.2	M240 T241 V244 F245 W412 S413 P414 L420	M240-F416 HydrophobicContact CB-CE1 4.34Å; T241-F416 HydrophobicContact CG2-CB 4.1Å; T241-F416 HydrophobicContact CG2-CD1 4.38Å; T241-F416 HydrophobicContact CG2-CG 4.42Å; T241-F416 VanDerWaalsContact OG1-CD1 3.23Å; T241-F416 WeakPolarHBondContact OG1-CD1 3.37Å; V244-F416 HydrophobicContact CB-CE1 4.5Å; V244-F416 HydrophobicContact CB-CE2 3.98Å; V244-F416 HydrophobicContact CB-CZ 3.56Å; V244-F416 HydrophobicContact CG1-CE2 3.69Å; V244-F416 HydrophobicContact CG1-CZ 3.62Å; V244-F416 HydrophobicContact CG2-CZ 4.23Å; F245-F416 HydrophobicContact CB-CD2 3.37Å; F245-F416 HydrophobicContact CB-CE2 3.63Å; F245-F416 HydrophobicContact CB-CG 4.07Å; F245-F416 HydrophobicContact CD1-CB 4.21Å; F245-F416 HydrophobicContact CD1-CD2 4.31Å; F245-F416 AromaticContact CG-CD2 3.9Å; F245-F416 HydrophobicContact CG-CD2 3.9Å; W412-F416 HydrophobicContact CB-CD2 4.26Å; W412-F416 HydrophobicContact CD2-CE2 4.19Å; W412-F416 HydrophobicContact CE3-CD2 4.02Å; W412-F416 AromaticContact CE3-CE2 3.42Å; W412-F416 HydrophobicContact CE3-CE2 3.42Å; W412-F416 VanDerWaalsContact CE3-CE2 3.42Å; W412-F416 HydrophobicContact CE3-CZ 4.29Å; W412-F416 HydrophobicContact CZ3-CE2 4.03Å; W412-F416 HydrophobicContact CZ3-CZ 4.49Å; W412-F416 WeakPolarHBondContact O-CD2 3.43Å; W412-F416 PolarHBondContact O-N 2.93Å; W412-F416 VanDerWaalsContact O-N 3.08Å; S413-F416 PolarHBondContact O-N 3.16Å; P414-F416 PolarHBondContact O-N 2.88Å; F416-L420 WeakPolarHBondContact O-CB 3.22Å; F416-L420 PolarHBondContact O-N 3.25Å
417	I	86.6	Confident	82	Confident	102 Å²	102	49.1 Å²	49.1	52%	0.523	26%	0.261	S	S	.	.	H	α-helix	trans	-64.2	-51.2	170.2	-72.3	165.9	0	0	0	109.9	S413 P414 Q419 L420 W421	S413-I417 WeakPolarHBondContact O-CB 3.47Å; S413-I417 WeakPolarHBondContact O-CD1 3.17Å; S413-I417 WeakPolarHBondContact O-CG1 3.44Å; S413-I417 PolarHBondContact O-N 3.48Å; S413-I417 WeakPolarHBondContact OG-CD1 3.21Å; P414-I417 PolarHBondContact O-N 3.02Å; I417-Q419 PolarHBondContact O-N 2.98Å; I417-L420 PolarHBondContact O-N 2.71Å; I417-W421 VanDerWaalsContact O-CB 3.31Å; I417-W421 WeakPolarHBondContact O-CB 3.35Å; I417-W421 PolarHBondContact O-N 2.97Å
418	V	79.9	Confident	80.6	Confident	11 Å²	11	50.1 Å²	50.1	7%	0.067	27%	0.269	C	S	.	.	H	α-helix	trans	-61	-45.8	179.9	169.5	0	0	0	0	111.4	P414 F415 W421 A422 F435 L438 M439	P414-V418 WeakPolarHBondContact O-CB 3.33Å; P414-V418 WeakPolarHBondContact O-CG2 3.44Å; P414-V418 PolarHBondContact O-N 3.38Å; F415-V418 PolarHBondContact O-N 2.8Å; V418-W421 PolarHBondContact O-N 3.03Å; V418-A422 WeakPolarHBondContact O-CB 3.44Å; V418-A422 PolarHBondContact O-N 3Å; V418-F435 HydrophobicContact CG1-CD2 3.68Å; V418-F435 HydrophobicContact CG1-CE1 4.37Å; V418-F435 HydrophobicContact CG1-CE2 3.25Å; V418-F435 HydrophobicContact CG1-CG 4.4Å; V418-F435 HydrophobicContact CG1-CZ 3.64Å; V418-L438 HydrophobicContact CG2-CB 4.01Å; V418-L438 HydrophobicContact CG2-CD1 3.91Å; V418-M439 HydrophobicContact CG1-SD 4.24Å
419	Q	77.9	Confident	79	Confident	4 Å²	4	52.9 Å²	52.9	2%	0.019	29%	0.286	C	S	.	.	H	α-helix	trans	-65.3	-43.5	179.4	-68.2	-83.4	79	0	0	112.1	V237 F415 I417 W421 A423 M439	V237-Q419 HydrophobicContact CG1-CB 4.23Å; V237-Q419 WeakPolarHBondContact CG1-O 3.23Å; F415-Q419 HydrophobicContact CD1-CG 4.43Å; F415-Q419 HydrophobicContact CD2-CG 4.22Å; F415-Q419 HydrophobicContact CE1-CG 4.12Å; F415-Q419 HydrophobicContact CE2-CG 3.9Å; F415-Q419 HydrophobicContact CG-CG 4.46Å; F415-Q419 HydrophobicContact CZ-CG 3.82Å; F415-Q419 WeakPolarHBondContact O-CB 3.37Å; F415-Q419 WeakPolarHBondContact O-CG 3.22Å; F415-Q419 PolarHBondContact O-N 2.94Å; I417-Q419 PolarHBondContact O-N 2.98Å; Q419-W421 VanDerWaalsContact C-N 3.35Å; Q419-A423 WeakPolarHBondContact O-CB 3.41Å; Q419-A423 PolarHBondContact O-N 3.04Å; Q419-A423 VanDerWaalsContact O-N 3.12Å; Q419-M439 HydrophobicContact CG-CE 4.24Å; Q419-M439 HydrophobicContact CG-SD 3.85Å
420	L	82.9	Confident	77.3	Confident	61 Å²	61	56.2 Å²	56.2	32%	0.319	30%	0.302	S	S	.	.	H	α-helix	trans	-65.1	-39.8	177.1	-174	69.2	0	0	0	111.3	T238 F416 I417 A423 W424	T238-L420 WeakPolarHBondContact OG1-CD1 3.4Å; F416-L420 WeakPolarHBondContact O-CB 3.22Å; F416-L420 PolarHBondContact O-N 3.25Å; I417-L420 PolarHBondContact O-N 2.71Å; L420-A423 PolarHBondContact O-N 3.45Å; L420-W424 VanDerWaalsContact O-CD1 3.26Å; L420-W424 PolarHBondContact O-N 3.48Å
421	W	81.9	Confident	75.8	Confident	121 Å²	121	53.8 Å²	53.8	46%	0.458	29%	0.285	S	S	.	.	H	α-helix	trans	-61.9	-54.2	176.3	-174.9	18.9	0	0	0	111.3	I417 V418 Q419 A423 W424 D425 P429	I417-W421 VanDerWaalsContact O-CB 3.31Å; I417-W421 WeakPolarHBondContact O-CB 3.35Å; I417-W421 PolarHBondContact O-N 2.97Å; V418-W421 PolarHBondContact O-N 3.03Å; Q419-W421 VanDerWaalsContact C-N 3.35Å; W421-A423 PolarHBondContact O-N 2.84Å; W421-A423 VanDerWaalsContact O-N 3.12Å; W421-W424 PolarHBondContact O-N 3.38Å; W421-D425 VanDerWaalsContact CD1-CB 3.5Å; W421-D425 PolarHBondContact NE1-OD2 3.28Å; W421-D425 WeakPolarHBondContact O-CB 3.22Å; W421-D425 PolarHBondContact O-N 2.93Å; W421-P429 HydrophobicContact CE3-CG 4.46Å; W421-P429 HydrophobicContact CH2-CB 4.29Å; W421-P429 VanDerWaalsContact CH2-CD 3.45Å; W421-P429 HydrophobicContact CH2-CG 3.45Å; W421-P429 VanDerWaalsContact CH2-CG 3.45Å; W421-P429 HydrophobicContact CZ2-CG 4.14Å; W421-P429 HydrophobicContact CZ3-CG 3.62Å
422	A	74.3	Confident	74.3	Confident	24 Å²	24	53.9 Å²	53.9	20%	0.198	29%	0.288	C	S	.	.	H	α-helix	trans	-64	-16.7	179.8	0	0	0	0	0	114.6	V418	V418-A422 WeakPolarHBondContact O-CB 3.44Å; V418-A422 PolarHBondContact O-N 3Å
423	A	74.9	Confident	73.1	Confident	8 Å²	8	54.6 Å²	54.6	7%	0.066	29%	0.293	C	S	.	.	H	α-helix	trans	-88.7	-22.7	173	0	0	0	0	0	113.4	K234 V237 Q419 L420 W421	K234-A423 WeakPolarHBondContact CD-O 3.3Å; K234-A423 WeakPolarHBondContact CE-O 3.42Å; K234-A423 WeakPolarHBondContact CG-O 3.28Å; V237-A423 HydrophobicContact CB-CB 3.81Å; V237-A423 HydrophobicContact CG1-CB 3.86Å; V237-A423 HydrophobicContact CG2-CB 3.9Å; Q419-A423 WeakPolarHBondContact O-CB 3.41Å; Q419-A423 PolarHBondContact O-N 3.04Å; Q419-A423 VanDerWaalsContact O-N 3.12Å; L420-A423 PolarHBondContact O-N 3.45Å; W421-A423 PolarHBondContact O-N 2.84Å; W421-A423 VanDerWaalsContact O-N 3.12Å
424	W	79.7	Confident	71.9	Confident	143 Å²	143	56.2 Å²	56.2	54%	0.542	31%	0.308	S	S	.	.	H	α-helix	trans	-106.2	-35.5	-172.6	-82	81.3	0	0	0	114.1	K234 T238 L420 W421	K234-W424 HydrophobicContact CB-CZ2 4.15Å; K234-W424 HydrophobicContact CD-CD2 4.11Å; K234-W424 HydrophobicContact CD-CE3 4.23Å; K234-W424 HydrophobicContact CD-CG 4.49Å; K234-W424 PolarHBondContact NZ-O 3.42Å; K234-W424 VanDerWaalsContact NZ-O 3.07Å; T238-W424 PolarHBondContact OG1-NE1 2.86Å; T238-W424 VanDerWaalsContact OG1-NE1 3.08Å; L420-W424 VanDerWaalsContact O-CD1 3.26Å; L420-W424 PolarHBondContact O-N 3.48Å; W421-W424 PolarHBondContact O-N 3.38Å
425	D	76.1	Confident	70.9	Confident	66 Å²	66	56.5 Å²	56.5	35%	0.353	31%	0.307	S	S	.	.			trans	-94.1	128.4	-177	-161.7	-5.6	0	0	0	111.3	W421	W421-D425 VanDerWaalsContact CD1-CB 3.5Å; W421-D425 PolarHBondContact NE1-OD2 3.28Å; W421-D425 WeakPolarHBondContact O-CB 3.22Å; W421-D425 PolarHBondContact O-N 2.93Å
426	P	64.8	Low	70	Confident	100 Å²	100	57.2 Å²	57.2	65%	0.649	31%	0.311	S	S	*	.	S	Bend	trans	-69.2	-26.9	180	26.7	-36.6	0	0	0	114.8	P428	P426-P428 WeakPolarHBondContact O-CD 3.42Å
427	D	61.7	Low	69.2	Low	137 Å²	137	60.6 Å²	60.6	73%	0.733	33%	0.329	S	S	*	.	S	Bend	trans	-116.1	67.5	-176.9	-66.9	-56.5	0	0	0	111.2
428	P	59.9	Low	68.5	Low	48 Å²	48	58.8 Å²	58.8	31%	0.312	32%	0.32	S	S	.	.			trans	-63.1	149.3	174.5	29.7	-35.4	0	0	0	110.7	P426	P426-P428 WeakPolarHBondContact O-CD 3.42Å
429	P	55.2	Low	67.9	Low	58 Å²	58	58.7 Å²	58.7	38%	0.377	32%	0.319	S	S	.	.			trans	-66.4	164.6	-175.9	32.5	-40.4	0	0	0	112.2	W421 Q431	W421-P429 HydrophobicContact CE3-CG 4.46Å; W421-P429 HydrophobicContact CH2-CB 4.29Å; W421-P429 VanDerWaalsContact CH2-CD 3.45Å; W421-P429 HydrophobicContact CH2-CG 3.45Å; W421-P429 VanDerWaalsContact CH2-CG 3.45Å; W421-P429 HydrophobicContact CZ2-CG 4.14Å; W421-P429 HydrophobicContact CZ3-CG 3.62Å; P429-Q431 PolarHBondContact O-N 2.89Å
430	D	54.3	Low	67.6	Low	121 Å²	121	59 Å²	59	65%	0.647	32%	0.321	S	S	*	.			trans	-45.5	132.2	176.3	-57.5	-49.9	0	0	0	111.5	G432	D430-G432 PolarHBondContact O-N 3.31Å
431	Q	56.6	Low	67.3	Low	38 Å²	38	58.1 Å²	58.1	18%	0.178	32%	0.316	C	S	.	.			trans	-79.4	40.4	-169.4	-62.7	179.4	-17.6	0	0	112.3	I38 P429	I38-Q431 WeakPolarHBondContact CB-O 3.39Å; I38-Q431 VanDerWaalsContact CG2-O 3.27Å; I38-Q431 WeakPolarHBondContact CG2-O 3.3Å; P429-Q431 PolarHBondContact O-N 2.89Å
432	G	59	Low	67	Low	13 Å²	13	52.4 Å²	52.4	13%	0.134	30%	0.295	C	S	.	.			trans	-64.3	176.1	-175.6	0	0	0	0	0	114.3	D430 A434 F435	D430-G432 PolarHBondContact O-N 3.31Å; G432-A434 PolarHBondContact O-N 2.98Å; G432-F435 VanDerWaalsContact O-CB 3.31Å; G432-F435 WeakPolarHBondContact O-CB 3.26Å; G432-F435 PolarHBondContact O-N 3.46Å
433	V	62.3	Low	67.1	Low	20 Å²	20	51.4 Å²	51.4	12%	0.121	29%	0.286	C	S	.	.	H	α-helix	trans	-53.5	-31.9	-173.5	-157.1	0	0	0	0	113.2	L33 F36 I38 L71 F435 T436 I437	L33-V433 HydrophobicContact CD2-CB 4.06Å; L33-V433 HydrophobicContact CD2-CG1 3.71Å; L33-V433 HydrophobicContact CD2-CG2 4.09Å; F36-V433 HydrophobicContact CB-CG2 4.26Å; F36-V433 HydrophobicContact CD2-CG2 4.47Å; I38-V433 HydrophobicContact CD1-CG2 3.75Å; L71-V433 HydrophobicContact CD1-CB 4.35Å; L71-V433 HydrophobicContact CD1-CG1 3.93Å; L71-V433 HydrophobicContact CD1-CG2 3.93Å; V433-F435 PolarHBondContact O-N 3.06Å; V433-T436 PolarHBondContact O-N 2.76Å; V433-I437 HydrophobicContact CG1-CD1 3.99Å; V433-I437 HydrophobicContact CG1-CG1 4.39Å; V433-I437 WeakPolarHBondContact O-CB 3.41Å; V433-I437 VanDerWaalsContact O-CG1 3.28Å; V433-I437 WeakPolarHBondContact O-CG1 3.22Å; V433-I437 PolarHBondContact O-N 3.22Å
434	A	65.3	Low	67.3	Low	67 Å²	67	54.1 Å²	54.1	55%	0.554	30%	0.299	S	S	*	.	H	α-helix	trans	-58.3	-42.6	174	0	0	0	0	0	112.9	G432 I437 L438	G432-A434 PolarHBondContact O-N 2.98Å; A434-I437 PolarHBondContact O-N 2.67Å; A434-L438 WeakPolarHBondContact O-CB 3.31Å; A434-L438 WeakPolarHBondContact O-CD1 3.48Å; A434-L438 WeakPolarHBondContact O-CG 3.27Å; A434-L438 PolarHBondContact O-N 2.82Å
435	F	65.8	Low	67.4	Low	32 Å²	32	47.4 Å²	47.4	14%	0.14	27%	0.274	C	S	.	.	H	α-helix	trans	-60.6	-50.2	177.5	-173.2	-81.1	0	0	0	110.8	L49 V418 G432 V433 I437 L438 M439	L49-F435 HydrophobicContact CD1-CE1 4.01Å; L49-F435 HydrophobicContact CD1-CZ 3.86Å; V418-F435 HydrophobicContact CG1-CD2 3.68Å; V418-F435 HydrophobicContact CG1-CE1 4.37Å; V418-F435 HydrophobicContact CG1-CE2 3.25Å; V418-F435 HydrophobicContact CG1-CG 4.4Å; V418-F435 HydrophobicContact CG1-CZ 3.64Å; G432-F435 VanDerWaalsContact O-CB 3.31Å; G432-F435 WeakPolarHBondContact O-CB 3.26Å; G432-F435 PolarHBondContact O-N 3.46Å; V433-F435 PolarHBondContact O-N 3.06Å; F435-I437 PolarHBondContact O-N 2.74Å; F435-L438 PolarHBondContact O-N 2.97Å; F435-M439 HydrophobicContact CD1-CG 4.1Å; F435-M439 HydrophobicContact CE1-CG 3.91Å; F435-M439 VanDerWaalsContact O-CG 3.31Å; F435-M439 WeakPolarHBondContact O-CG 3.38Å; F435-M439 PolarHBondContact O-N 3.36Å
436	T	65.7	Low	67.8	Low	19 Å²	19	44.4 Å²	44.4	12%	0.117	26%	0.258	C	S	.	.	H	α-helix	trans	-58.8	-45.1	176.3	-59.1	0	0	0	0	111.9	E75 V433 M439 L440	E75-T436 HydrophobicContact CG-CG2 4.16Å; E75-T436 WeakPolarHBondContact OE1-CG2 3.44Å; V433-T436 PolarHBondContact O-N 2.76Å; T436-M439 PolarHBondContact O-N 2.93Å; T436-L440 HydrophobicContact CG2-CD1 3.76Å; T436-L440 HydrophobicContact CG2-CG 4.44Å; T436-L440 WeakPolarHBondContact O-CB 3.49Å; T436-L440 WeakPolarHBondContact O-CD1 3.28Å; T436-L440 VanDerWaalsContact O-CG 3.26Å; T436-L440 WeakPolarHBondContact O-CG 3.35Å; T436-L440 PolarHBondContact O-N 3.37Å
437	I	69.2	Low	68.7	Low	80 Å²	80	40.1 Å²	40.1	41%	0.41	23%	0.23	S	C	.	.	H	α-helix	trans	-60.5	-48.3	176.7	-71.1	166.1	0	0	0	111.1	V433 A434 F435 M439 L440 L441	V433-I437 HydrophobicContact CG1-CD1 3.99Å; V433-I437 HydrophobicContact CG1-CG1 4.39Å; V433-I437 WeakPolarHBondContact O-CB 3.41Å; V433-I437 VanDerWaalsContact O-CG1 3.28Å; V433-I437 WeakPolarHBondContact O-CG1 3.22Å; V433-I437 PolarHBondContact O-N 3.22Å; A434-I437 PolarHBondContact O-N 2.67Å; F435-I437 PolarHBondContact O-N 2.74Å; I437-M439 VanDerWaalsContact C-N 3.25Å; I437-M439 PolarHBondContact O-N 3.39Å; I437-L440 PolarHBondContact O-N 2.79Å; I437-L440 VanDerWaalsContact O-N 3.13Å; I437-L441 WeakPolarHBondContact O-CG 3.49Å; I437-L441 PolarHBondContact O-N 2.84Å; I437-L441 VanDerWaalsContact O-N 3.16Å
438	L	71.4	Confident	69.8	Low	63 Å²	63	35.5 Å²	35.5	33%	0.33	21%	0.208	S	C	.	.	H	α-helix	trans	-61.6	-34.3	-179.8	-67	162.5	0	0	0	112	P414 V418 A434 F435 L441	P414-L438 HydrophobicContact CB-CB 4.39Å; P414-L438 HydrophobicContact CB-CD2 3.7Å; V418-L438 HydrophobicContact CG2-CB 4.01Å; V418-L438 HydrophobicContact CG2-CD1 3.91Å; A434-L438 WeakPolarHBondContact O-CB 3.31Å; A434-L438 WeakPolarHBondContact O-CD1 3.48Å; A434-L438 WeakPolarHBondContact O-CG 3.27Å; A434-L438 PolarHBondContact O-N 2.82Å; F435-L438 PolarHBondContact O-N 2.97Å; L438-L441 HydrophobicContact CD2-CD1 4.37Å
439	M	68	Low	70.9	Confident	9 Å²	9	33.4 Å²	33.4	4%	0.044	19%	0.194	C	C	.	.	H	α-helix	trans	-69.6	-41.7	173.8	-70.8	-71.5	-78	0	0	112.4	L45 F415 V418 Q419 F435 T436 I437 L441	L45-M439 HydrophobicContact CB-CE 4.18Å; L45-M439 HydrophobicContact CD1-CB 4.38Å; F415-M439 HydrophobicContact CD2-CE 4.1Å; F415-M439 HydrophobicContact CD2-SD 3.57Å; F415-M439 VanDerWaalsContact CD2-SD 3.57Å; F415-M439 HydrophobicContact CE2-CE 3.7Å; F415-M439 HydrophobicContact CE2-SD 3.78Å; V418-M439 HydrophobicContact CG1-SD 4.24Å; Q419-M439 HydrophobicContact CG-CE 4.24Å; Q419-M439 HydrophobicContact CG-SD 3.85Å; F435-M439 HydrophobicContact CD1-CG 4.1Å; F435-M439 HydrophobicContact CE1-CG 3.91Å; F435-M439 VanDerWaalsContact O-CG 3.31Å; F435-M439 WeakPolarHBondContact O-CG 3.38Å; F435-M439 PolarHBondContact O-N 3.36Å; T436-M439 PolarHBondContact O-N 2.93Å; I437-M439 VanDerWaalsContact C-N 3.25Å; I437-M439 PolarHBondContact O-N 3.39Å; M439-L441 VanDerWaalsContact C-N 3.29Å; M439-L441 PolarHBondContact O-N 3.46Å
440	L	70.3	Confident	72.3	Confident	11 Å²	11	31.1 Å²	31.1	6%	0.058	18%	0.179	C	C	.	.	H	α-helix	trans	-68.4	-21.5	179.8	-72	164.5	0	0	0	113.8	L45 I78 L79 T436 I437 A442 S443	L45-L440 HydrophobicContact CD1-CD2 3.96Å; L45-L440 HydrophobicContact CD1-CG 4.4Å; I78-L440 HydrophobicContact CB-CD1 4.49Å; I78-L440 HydrophobicContact CG2-CD1 3.94Å; L79-L440 HydrophobicContact CD2-CD2 3.53Å; L79-L440 HydrophobicContact CG-CD2 3.93Å; T436-L440 HydrophobicContact CG2-CD1 3.76Å; T436-L440 HydrophobicContact CG2-CG 4.44Å; T436-L440 WeakPolarHBondContact O-CB 3.49Å; T436-L440 WeakPolarHBondContact O-CD1 3.28Å; T436-L440 VanDerWaalsContact O-CG 3.26Å; T436-L440 WeakPolarHBondContact O-CG 3.35Å; T436-L440 PolarHBondContact O-N 3.37Å; I437-L440 PolarHBondContact O-N 2.79Å; I437-L440 VanDerWaalsContact O-N 3.13Å; L440-A442 PolarHBondContact O-N 3.02Å; L440-S443 WeakPolarHBondContact O-CB 3.34Å; L440-S443 PolarHBondContact O-N 3.03Å; L440-S443 VanDerWaalsContact O-N 3.13Å
441	L	76.9	Confident	73.6	Confident	43 Å²	43	34 Å²	34	23%	0.225	18%	0.181	C	C	.	.	G	3₁₀ helix	trans	-58.3	-31.3	178.8	-72.4	178.4	0	0	0	113.5	C411 P414 I437 L438 M439 S443 L444	C411-L441 WeakPolarHBondContact CB-O 3.31Å; C411-L441 CarbonylContact O-C 3.39Å; P414-L441 HydrophobicContact CB-CD1 3.89Å; P414-L441 HydrophobicContact CG-CD1 3.73Å; I437-L441 WeakPolarHBondContact O-CG 3.49Å; I437-L441 PolarHBondContact O-N 2.84Å; I437-L441 VanDerWaalsContact O-N 3.16Å; L438-L441 HydrophobicContact CD2-CD1 4.37Å; M439-L441 VanDerWaalsContact C-N 3.29Å; M439-L441 PolarHBondContact O-N 3.46Å; L441-S443 VanDerWaalsContact C-N 3.29Å; L441-S443 PolarHBondContact O-N 3.15Å; L441-L444 HydrophobicContact CD2-CD1 3.77Å; L441-L444 WeakPolarHBondContact O-CB 3.21Å; L441-L444 PolarHBondContact O-N 3.34Å; L441-L444 VanDerWaalsContact O-N 3.14Å
442	A	76	Confident	74.7	Confident	1 Å²	1	32.6 Å²	32.6	1%	0.008	17%	0.174	C	C	.	.	G	3₁₀ helix	trans	-57.1	-42	176.1	0	0	0	0	0	112.1	C411 W412 F415 L440 L444 N445	C411-A442 WeakPolarHBondContact O-CA 3.48Å; C411-A442 PolarHBondContact O-N 3.24Å; W412-A442 HydrophobicContact CE3-CB 3.88Å; W412-A442 HydrophobicContact CH2-CB 4.05Å; W412-A442 HydrophobicContact CZ3-CB 3.55Å; F415-A442 HydrophobicContact CB-CB 3.96Å; F415-A442 HydrophobicContact CD1-CB 4.46Å; F415-A442 HydrophobicContact CD2-CB 4.1Å; F415-A442 HydrophobicContact CG-CB 3.92Å; L440-A442 PolarHBondContact O-N 3.02Å; A442-L444 PolarHBondContact O-N 2.82Å; A442-N445 VanDerWaalsContact O-CB 3.29Å; A442-N445 WeakPolarHBondContact O-CB 3.4Å; A442-N445 PolarHBondContact O-N 2.82Å
443	S	75.3	Confident	75.5	Confident	2 Å²	2	32.1 Å²	32.1	1%	0.014	17%	0.168	C	C	.	.	G	3₁₀ helix	trans	-67	-23.9	-179.6	-53.8	0	0	0	0	113	L440 L441 N445 S446 C447	L440-S443 WeakPolarHBondContact O-CB 3.34Å; L440-S443 PolarHBondContact O-N 3.03Å; L440-S443 VanDerWaalsContact O-N 3.13Å; L441-S443 VanDerWaalsContact C-N 3.29Å; L441-S443 PolarHBondContact O-N 3.15Å; S443-N445 PolarHBondContact O-N 3.26Å; S443-S446 PolarHBondContact O-N 2.94Å; S443-C447 PolarHBondContact O-N 3.02Å
444	L	79.5	Confident	76.1	Confident	65 Å²	65	32.7 Å²	32.7	34%	0.34	17%	0.172	S	C	.	.	H	α-helix	trans	-69.3	-18.6	177.6	-59.3	-176.8	0	0	0	113.3	V82 L441 A442 S446 C447 T448	V82-L444 HydrophobicContact CG2-CD2 4.16Å; L441-L444 HydrophobicContact CD2-CD1 3.77Å; L441-L444 WeakPolarHBondContact O-CB 3.21Å; L441-L444 PolarHBondContact O-N 3.34Å; L441-L444 VanDerWaalsContact O-N 3.14Å; A442-L444 PolarHBondContact O-N 2.82Å; L444-S446 VanDerWaalsContact C-N 3.3Å; L444-S446 PolarHBondContact O-N 3.44Å; L444-C447 HydrophobicContact CD2-CB 4.47Å; L444-C447 PolarHBondContact O-N 2.91Å; L444-T448 WeakPolarHBondContact O-CB 2.96Å; L444-T448 WeakPolarHBondContact O-CG2 3.3Å; L444-T448 PolarHBondContact O-N 2.82Å; L444-T448 PolarHBondContact O-OG1 2.99Å
445	N	83.1	Confident	76.5	Confident	2 Å²	2	32 Å²	32	1%	0.011	17%	0.167	C	C	.	.	H	α-helix	trans	-57.9	-44	172.5	-176.4	76.1	0	0	0	110.9	C411 W412 A442 S443 T448 N449	C411-N445 HydrophobicContact CB-CB 3.86Å; W412-N445 HydrophobicContact CZ2-CB 4.39Å; A442-N445 VanDerWaalsContact O-CB 3.29Å; A442-N445 WeakPolarHBondContact O-CB 3.4Å; A442-N445 PolarHBondContact O-N 2.82Å; S443-N445 PolarHBondContact O-N 3.26Å; N445-T448 PolarHBondContact O-OG1 2.89Å; N445-N449 PolarHBondContact O-ND2 3.01Å
446	S	84.7	Confident	76.6	Confident	3 Å²	3	32 Å²	32	2%	0.021	17%	0.167	C	C	.	.	H	α-helix	trans	-77.8	-28.4	178.2	-61.5	0	0	0	0	113.2	N90 D118 S443 L444 T448	N90-S446 PolarHBondContact ND2-O 3.28Å; N90-S446 VanDerWaalsContact ND2-O 3.12Å; D118-S446 WeakPolarHBondContact OD1-CB 3.48Å; D118-S446 PolarHBondContact OD1-OG 3.37Å; S443-S446 PolarHBondContact O-N 2.94Å; L444-S446 VanDerWaalsContact C-N 3.3Å; L444-S446 PolarHBondContact O-N 3.44Å; S446-T448 VanDerWaalsContact C-N 3.34Å
447	C	83.2	Confident	76.8	Confident	10 Å²	10	31.7 Å²	31.7	7%	0.068	17%	0.165	C	C	.	.	H	α-helix	trans	-66.2	-32.4	172.2	-67.5	0	0	0	0	113.4	T86 S443 L444	T86-C447 PolarHBondContact OG1-SG 3.14Å; S443-C447 PolarHBondContact O-N 3.02Å; L444-C447 HydrophobicContact CD2-CB 4.47Å; L444-C447 PolarHBondContact O-N 2.91Å
448	T	84	Confident	76.6	Confident	41 Å²	41	31.3 Å²	31.3	25%	0.252	17%	0.169	S	C	.	.	H	α-helix	trans	-87.9	-23.8	-170.6	44.9	0	0	0	0	113.7	V407 L444 N445 S446 W451 I452	V407-T448 HydrophobicContact CG1-CG2 4.4Å; V407-T448 WeakPolarHBondContact CG1-OG1 3.44Å; L444-T448 WeakPolarHBondContact O-CB 2.96Å; L444-T448 WeakPolarHBondContact O-CG2 3.3Å; L444-T448 PolarHBondContact O-N 2.82Å; L444-T448 PolarHBondContact O-OG1 2.99Å; N445-T448 PolarHBondContact O-OG1 2.89Å; S446-T448 VanDerWaalsContact C-N 3.34Å; T448-W451 WeakPolarHBondContact O-CB 3.17Å; T448-W451 PolarHBondContact O-N 2.87Å; T448-I452 PolarHBondContact O-N 3.25Å
449	N	84	Confident	76.3	Confident	3 Å²	3	31.6 Å²	31.6	2%	0.016	18%	0.177	C	C	.	.	H	α-helix	trans	-52.7	-45.6	-179.8	-74.3	-31.2	0	0	0	114.4	L114 D118 N445 W451 I452 Y453	L114-N449 HydrophobicContact CD2-CB 4.34Å; L114-N449 WeakPolarHBondContact CD2-ND2 3.48Å; D118-N449 PolarHBondContact OD2-ND2 3.44Å; N445-N449 PolarHBondContact O-ND2 3.01Å; N449-W451 VanDerWaalsContact C-N 3.29Å; N449-W451 PolarHBondContact O-N 3.46Å; N449-I452 PolarHBondContact O-N 3.43Å; N449-Y453 HydrophobicContact CB-CE2 4.32Å; N449-Y453 WeakPolarHBondContact O-CD2 3.48Å; N449-Y453 PolarHBondContact O-N 2.81Å
450	P	83.9	Confident	76.2	Confident	10 Å²	10	31.3 Å²	31.3	7%	0.065	18%	0.176	C	C	.	.	H	α-helix	trans	-55	-38.2	172.7	-29.7	37	0	0	0	114.6	V93 Y453 T454	V93-P450 HydrophobicContact CG2-CB 3.97Å; P450-Y453 PolarHBondContact O-N 3.32Å; P450-T454 WeakPolarHBondContact O-CG2 3.23Å; P450-T454 PolarHBondContact O-N 2.87Å; P450-T454 PolarHBondContact O-OG1 3.34Å
451	W	80.7	Confident	76.1	Confident	182 Å²	182	32.1 Å²	32.1	69%	0.689	18%	0.182	S	C	*	.	H	α-helix	trans	-74	-36.1	179.4	-59.9	96.4	0	0	0	112.4	T448 N449 Y453 T454 A455	T448-W451 WeakPolarHBondContact O-CB 3.17Å; T448-W451 PolarHBondContact O-N 2.87Å; N449-W451 VanDerWaalsContact C-N 3.29Å; N449-W451 PolarHBondContact O-N 3.46Å; W451-Y453 VanDerWaalsContact C-N 3.27Å; W451-Y453 PolarHBondContact O-N 2.89Å; W451-T454 WeakPolarHBondContact CA-OG1 3.41Å; W451-T454 PolarHBondContact O-N 3.29Å; W451-T454 PolarHBondContact O-OG1 3.47Å; W451-A455 WeakPolarHBondContact O-CB 3.36Å; W451-A455 PolarHBondContact O-N 2.69Å
452	I	80.7	Confident	75.7	Confident	9 Å²	9	33.3 Å²	33.3	5%	0.046	19%	0.191	C	C	.	.	H	α-helix	trans	-61.3	-41	170.2	-61.6	173.1	0	0	0	109.3	M400 V403 I404 V407 T448 N449 F456	M400-I452 HydrophobicContact CE-CG2 3.96Å; M400-I452 HydrophobicContact CG-CG2 4.04Å; V403-I452 HydrophobicContact CG1-CD1 4.41Å; V403-I452 HydrophobicContact CG1-CG1 4.21Å; I404-I452 HydrophobicContact CD1-CG2 4.18Å; I404-I452 HydrophobicContact CG1-CD1 4.07Å; I404-I452 HydrophobicContact CG1-CG2 3.77Å; V407-I452 HydrophobicContact CB-CD1 4.41Å; V407-I452 HydrophobicContact CG1-CD1 4.36Å; V407-I452 HydrophobicContact CG2-CD1 4.31Å; T448-I452 PolarHBondContact O-N 3.25Å; N449-I452 PolarHBondContact O-N 3.43Å; I452-F456 HydrophobicContact CG2-CD2 3.96Å; I452-F456 WeakPolarHBondContact O-CB 3.19Å; I452-F456 VanDerWaalsContact O-CD2 3.27Å; I452-F456 WeakPolarHBondContact O-CD2 3.48Å; I452-F456 PolarHBondContact O-N 3.21Å
453	Y	76.3	Confident	75.5	Confident	2 Å²	2	34.6 Å²	34.6	1%	0.008	20%	0.197	C	C	.	.	H	α-helix	trans	-68.3	-43	177.1	-61.7	-36.2	0	0	0	113.6	V93 M111 L114 M400 N449 P450 W451 S457	V93-Y453 HydrophobicContact CG1-CD2 4Å; M111-Y453 HydrophobicContact CB-CE1 4.31Å; M111-Y453 HydrophobicContact CB-CE2 4.29Å; M111-Y453 HydrophobicContact CE-CD1 4.38Å; M111-Y453 HydrophobicContact CG-CD1 3.98Å; M111-Y453 HydrophobicContact CG-CE1 3.59Å; M111-Y453 HydrophobicContact CG-CE2 4.41Å; M111-Y453 HydrophobicContact SD-CD1 3.95Å; M111-Y453 HydrophobicContact SD-CE1 4.19Å; M111-Y453 HydrophobicContact SD-CG 4.36Å; L114-Y453 WeakPolarHBondContact CB-OH 3.31Å; L114-Y453 WeakPolarHBondContact CD2-OH 3.31Å; M400-Y453 HydrophobicContact CE-CD1 3.5Å; M400-Y453 HydrophobicContact CE-CE1 3.74Å; N449-Y453 HydrophobicContact CB-CE2 4.32Å; N449-Y453 WeakPolarHBondContact O-CD2 3.48Å; N449-Y453 PolarHBondContact O-N 2.81Å; P450-Y453 PolarHBondContact O-N 3.32Å; W451-Y453 VanDerWaalsContact C-N 3.27Å; W451-Y453 PolarHBondContact O-N 2.89Å; Y453-S457 WeakPolarHBondContact O-CA 3.31Å; Y453-S457 WeakPolarHBondContact O-CB 3.21Å; Y453-S457 PolarHBondContact O-N 2.68Å
454	T	74.8	Confident	75.2	Confident	33 Å²	33	36.8 Å²	36.8	20%	0.202	21%	0.208	C	C	.	.	H	α-helix	trans	-68.5	-34.4	177	55.9	0	0	0	0	112.8	P450 W451 V460 S461 L464	P450-T454 WeakPolarHBondContact O-CG2 3.23Å; P450-T454 PolarHBondContact O-N 2.87Å; P450-T454 PolarHBondContact O-OG1 3.34Å; W451-T454 WeakPolarHBondContact CA-OG1 3.41Å; W451-T454 PolarHBondContact O-N 3.29Å; W451-T454 PolarHBondContact O-OG1 3.47Å; T454-V460 HydrophobicContact CG2-CG1 4.01Å; T454-S461 VanDerWaalsContact O-CB 3.24Å; T454-S461 WeakPolarHBondContact O-CB 3.48Å; T454-L464 HydrophobicContact CG2-CD2 3.83Å
455	A	72.3	Confident	74.7	Confident	53 Å²	53	38.5 Å²	38.5	44%	0.438	22%	0.215	S	C	.	.	H	α-helix	trans	-72.1	-46.6	175	0	0	0	0	0	112.5	K396 W451	K396-A455 WeakPolarHBondContact CE-O 3.19Å; K396-A455 PolarHBondContact NZ-O 2.88Å; W451-A455 WeakPolarHBondContact O-CB 3.36Å; W451-A455 PolarHBondContact O-N 2.69Å
456	F	69.7	Low	74.1	Confident	31 Å²	31	42 Å²	42	14%	0.136	23%	0.233	C	C	.	.	H	α-helix	trans	-102.9	-29.6	-166.5	-62.8	-73.4	0	0	0	115.2	K396 R399 M400 V403 I452 S458	K396-F456 VanDerWaalsContact CD-O 3.23Å; K396-F456 WeakPolarHBondContact CD-O 3.25Å; K396-F456 WeakPolarHBondContact CE-O 3.33Å; K396-F456 HydrophobicContact CG-CD1 4.48Å; K396-F456 VanDerWaalsContact NZ-C 3.26Å; K396-F456 PolarHBondContact NZ-O 3.14Å; R399-F456 HydrophobicContact CB-CE1 4.23Å; R399-F456 HydrophobicContact CG-CE1 3.87Å; R399-F456 HydrophobicContact CG-CZ 4.48Å; M400-F456 HydrophobicContact CB-CB 3.59Å; M400-F456 HydrophobicContact CB-CD1 4Å; M400-F456 HydrophobicContact CB-CD2 4.29Å; M400-F456 HydrophobicContact CB-CG 3.68Å; M400-F456 HydrophobicContact CE-CB 4.23Å; M400-F456 HydrophobicContact CG-CB 3.39Å; M400-F456 HydrophobicContact CG-CD2 4.08Å; M400-F456 HydrophobicContact CG-CG 3.77Å; M400-F456 HydrophobicContact SD-CB 3.61Å; V403-F456 HydrophobicContact CB-CE2 4.09Å; V403-F456 HydrophobicContact CB-CZ 4.34Å; V403-F456 HydrophobicContact CG1-CE2 4.04Å; V403-F456 HydrophobicContact CG2-CE2 4.03Å; V403-F456 HydrophobicContact CG2-CZ 3.81Å; I452-F456 HydrophobicContact CG2-CD2 3.96Å; I452-F456 WeakPolarHBondContact O-CB 3.19Å; I452-F456 VanDerWaalsContact O-CD2 3.27Å; I452-F456 WeakPolarHBondContact O-CD2 3.48Å; I452-F456 PolarHBondContact O-N 3.21Å; F456-S458 PolarHBondContact O-N 3.1Å
457	S	69.6	Low	73.4	Confident	13 Å²	13	44.9 Å²	44.9	9%	0.091	25%	0.248	C	C	.	.			trans	-82.2	107.8	172.5	-172.2	0	0	0	0	110.7	Y453 S459 V460 S461	Y453-S457 WeakPolarHBondContact O-CA 3.31Å; Y453-S457 WeakPolarHBondContact O-CB 3.21Å; Y453-S457 PolarHBondContact O-N 2.68Å; S457-S459 PolarHBondContact O-N 3.19Å; S457-V460 PolarHBondContact O-N 3.4Å; S457-V460 VanDerWaalsContact O-N 3.08Å; S457-S461 PolarHBondContact O-N 2.89Å
458	S	63.8	Low	72.7	Confident	71 Å²	71	50.6 Å²	50.6	50%	0.497	28%	0.277	S	S	.	.	H	α-helix	trans	-61	-28.9	175.2	39.8	0	0	0	0	112.9	F456 V460 S461 T462	F456-S458 PolarHBondContact O-N 3.1Å; S458-V460 VanDerWaalsContact C-N 3.31Å; S458-V460 PolarHBondContact O-N 3.3Å; S458-S461 WeakPolarHBondContact CA-OG 3.27Å; S458-S461 PolarHBondContact O-OG 2.99Å; S458-T462 WeakPolarHBondContact O-CB 3.41Å; S458-T462 PolarHBondContact O-N 3.15Å; S458-T462 VanDerWaalsContact O-N 3.15Å; S458-T462 PolarHBondContact O-OG1 3.24Å
459	S	64.7	Low	72.2	Confident	69 Å²	69	55.3 Å²	55.3	48%	0.483	30%	0.297	S	S	.	.	H	α-helix	trans	-69.2	-28.6	175.6	-165.8	0	0	0	0	112.9	S457 E463	S457-S459 PolarHBondContact O-N 3.19Å; S459-E463 WeakPolarHBondContact O-CB 3.46Å
460	V	65.9	Low	70.7	Confident	4 Å²	4	60 Å²	60	2%	0.024	33%	0.329	C	S	.	.	H	α-helix	trans	-86.6	-43.5	176.9	179.9	0	0	0	0	110	L97 T454 S457 S458 T462 E463 L464	L97-V460 HydrophobicContact CD2-CG2 4.26Å; T454-V460 HydrophobicContact CG2-CG1 4.01Å; S457-V460 PolarHBondContact O-N 3.4Å; S457-V460 VanDerWaalsContact O-N 3.08Å; S458-V460 VanDerWaalsContact C-N 3.31Å; S458-V460 PolarHBondContact O-N 3.3Å; V460-T462 PolarHBondContact O-N 3.25Å; V460-E463 PolarHBondContact O-N 3.18Å; V460-L464 WeakPolarHBondContact O-CB 3.39Å; V460-L464 PolarHBondContact O-N 3.21Å
461	S	69.8	Low	69.1	Low	28 Å²	28	70.3 Å²	70.3	20%	0.196	37%	0.366	C	S	.	.	H	α-helix	trans	-59.3	-45.9	-179.8	71.4	0	0	0	0	112.6	T454 S457 S458 Q465	T454-S461 VanDerWaalsContact O-CB 3.24Å; T454-S461 WeakPolarHBondContact O-CB 3.48Å; S457-S461 PolarHBondContact O-N 2.89Å; S458-S461 WeakPolarHBondContact CA-OG 3.27Å; S458-S461 PolarHBondContact O-OG 2.99Å; S461-Q465 VanDerWaalsContact O-CG 3.31Å; S461-Q465 WeakPolarHBondContact O-CG 3.41Å; S461-Q465 PolarHBondContact O-N 3.23Å
462	T	67.9	Low	67.4	Low	68 Å²	68	66.9 Å²	66.9	42%	0.417	37%	0.37	S	S	.	.	H	α-helix	trans	-74.1	-29.6	-179.1	-62.8	0	0	0	0	112.2	S458 V460 Q465 N466	S458-T462 WeakPolarHBondContact O-CB 3.41Å; S458-T462 PolarHBondContact O-N 3.15Å; S458-T462 VanDerWaalsContact O-N 3.15Å; S458-T462 PolarHBondContact O-OG1 3.24Å; V460-T462 PolarHBondContact O-N 3.25Å; T462-Q465 PolarHBondContact O-N 2.98Å; T462-N466 PolarHBondContact O-N 3.08Å; T462-N466 PolarHBondContact O-ND2 3.13Å
463	E	70.6	Confident	65.8	Low	27 Å²	27	77.8 Å²	77.8	13%	0.126	41%	0.411	C	S	.	.	H	α-helix	trans	-76.8	-36.4	175	-169.8	70.1	160.6	0	0	112.3	V96 R100 S459 V460 Q465 N466 L467	V96-E463 HydrophobicContact CG1-CB 4.34Å; V96-E463 HydrophobicContact CG1-CG 4Å; R100-E463 IonicContact CZ-OE1 3.87Å; R100-E463 IonicContact CZ-OE2 3.5Å; R100-E463 IonicContact NE-OE1 3.69Å; R100-E463 PolarHBondContact NE-OE1 2.84Å; R100-E463 IonicContact NE-OE2 2.71Å; R100-E463 IonicContact NH2-OE1 3.93Å; R100-E463 PolarHBondContact NH2-OE1 2.76Å; R100-E463 IonicContact NH2-OE2 2.72Å; R100-E463 PolarHBondContact NH2-OE2 2.81Å; S459-E463 WeakPolarHBondContact O-CB 3.46Å; V460-E463 PolarHBondContact O-N 3.18Å; E463-Q465 VanDerWaalsContact C-N 3.27Å; E463-Q465 PolarHBondContact O-N 3.11Å; E463-N466 WeakPolarHBondContact O-CB 3.16Å; E463-N466 PolarHBondContact O-N 3.28Å; E463-N466 PolarHBondContact OE2-ND2 3.46Å; E463-L467 HydrophobicContact CG-CD1 4.33Å; E463-L467 WeakPolarHBondContact O-CB 3.27Å; E463-L467 VanDerWaalsContact O-CG 3.3Å; E463-L467 WeakPolarHBondContact O-CG 3.14Å; E463-L467 PolarHBondContact O-N 3.03Å
464	L	69.5	Low	64.2	Low	48 Å²	48	85.6 Å²	85.6	25%	0.251	45%	0.451	S	S	.	.	H	α-helix	trans	-58.7	-42.2	168.6	179.1	59.9	0	0	0	110.6	F92 T454 V460 L467 L468	F92-L464 HydrophobicContact CE1-CD1 4.02Å; F92-L464 HydrophobicContact CZ-CD1 3.95Å; T454-L464 HydrophobicContact CG2-CD2 3.83Å; V460-L464 WeakPolarHBondContact O-CB 3.39Å; V460-L464 PolarHBondContact O-N 3.21Å; L464-L467 PolarHBondContact O-N 2.94Å; L464-L468 HydrophobicContact CD1-CD1 3.84Å; L464-L468 HydrophobicContact CD1-CG 4.05Å; L464-L468 HydrophobicContact CG-CD1 3.85Å; L464-L468 HydrophobicContact CG-CG 4.45Å; L464-L468 WeakPolarHBondContact O-CB 3.05Å; L464-L468 VanDerWaalsContact O-CG 3.25Å; L464-L468 WeakPolarHBondContact O-CG 3.21Å; L464-L468 PolarHBondContact O-N 2.87Å
465	Q	69.4	Low	62.8	Low	102 Å²	102	87.4 Å²	87.4	48%	0.477	48%	0.477	S	S	.	.	H	α-helix	trans	-61.8	-46.4	171.6	-73.1	169.1	-24.3	0	0	112.2	S461 T462 E463 L467 L468 Q469	S461-Q465 VanDerWaalsContact O-CG 3.31Å; S461-Q465 WeakPolarHBondContact O-CG 3.41Å; S461-Q465 PolarHBondContact O-N 3.23Å; T462-Q465 PolarHBondContact O-N 2.98Å; E463-Q465 VanDerWaalsContact C-N 3.27Å; E463-Q465 PolarHBondContact O-N 3.11Å; Q465-L467 VanDerWaalsContact C-N 3.29Å; Q465-L467 PolarHBondContact O-N 3.41Å; Q465-L468 PolarHBondContact O-N 2.96Å; Q465-Q469 WeakPolarHBondContact O-CB 3.27Å; Q465-Q469 WeakPolarHBondContact O-CG 3.39Å; Q465-Q469 PolarHBondContact O-N 3.08Å
466	N	71.3	Confident	61.2	Low	74 Å²	74	96.9 Å²	96.9	40%	0.396	50%	0.501	S	S	.	.	H	α-helix	trans	-58.9	-38	177.1	-69.8	-31.5	0	0	0	113	T462 E463	T462-N466 PolarHBondContact O-N 3.08Å; T462-N466 PolarHBondContact O-ND2 3.13Å; E463-N466 WeakPolarHBondContact O-CB 3.16Å; E463-N466 PolarHBondContact O-N 3.28Å; E463-N466 PolarHBondContact OE2-ND2 3.46Å
467	L	69.1	Low	59.7	Low	64 Å²	64	106.7 Å²	106.7	34%	0.335	54%	0.537	S	S	.	.	H	α-helix	trans	-73.2	-46.8	178.8	-70.2	168.6	0	0	0	111.4	F92 W95 V96 E463 L464 Q465 Q469 C470	F92-L467 HydrophobicContact CZ-CD1 4.29Å; W95-L467 HydrophobicContact CZ3-CD1 4.2Å; V96-L467 HydrophobicContact CG2-CD1 4.14Å; E463-L467 HydrophobicContact CG-CD1 4.33Å; E463-L467 WeakPolarHBondContact O-CB 3.27Å; E463-L467 VanDerWaalsContact O-CG 3.3Å; E463-L467 WeakPolarHBondContact O-CG 3.14Å; E463-L467 PolarHBondContact O-N 3.03Å; L464-L467 PolarHBondContact O-N 2.94Å; Q465-L467 VanDerWaalsContact C-N 3.29Å; Q465-L467 PolarHBondContact O-N 3.41Å; L467-Q469 VanDerWaalsContact C-N 3.3Å; L467-Q469 PolarHBondContact O-N 3.04Å; L467-C470 PolarHBondContact O-N 3.21Å
468	L	68.8	Low	58.4	Low	130 Å²	130	109.5 Å²	109.5	68%	0.681	57%	0.568	S	S	*	*	H	α-helix	trans	-67.6	-27	177	-68.9	172.1	0	0	0	113.2	L464 Q465 C470	L464-L468 HydrophobicContact CD1-CD1 3.84Å; L464-L468 HydrophobicContact CD1-CG 4.05Å; L464-L468 HydrophobicContact CG-CD1 3.85Å; L464-L468 HydrophobicContact CG-CG 4.45Å; L464-L468 WeakPolarHBondContact O-CB 3.05Å; L464-L468 VanDerWaalsContact O-CG 3.25Å; L464-L468 WeakPolarHBondContact O-CG 3.21Å; L464-L468 PolarHBondContact O-N 2.87Å; Q465-L468 PolarHBondContact O-N 2.96Å; L468-C470 VanDerWaalsContact C-N 3.26Å; L468-C470 PolarHBondContact O-N 3.48Å
469	Q	73.1	Confident	56.9	Low	140 Å²	140	111.5 Å²	111.5	65%	0.654	58%	0.582	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.6	7.5	176.3	-69.5	173.3	3	0	0	113.5	Q465 L467 R471	Q465-Q469 WeakPolarHBondContact O-CB 3.27Å; Q465-Q469 WeakPolarHBondContact O-CG 3.39Å; Q465-Q469 PolarHBondContact O-N 3.08Å; L467-Q469 VanDerWaalsContact C-N 3.3Å; L467-Q469 PolarHBondContact O-N 3.04Å; Q469-R471 VanDerWaalsContact C-N 3.26Å; Q469-R471 PolarHBondContact O-N 3.05Å
470	C	53.6	Low	55.7	Low	102 Å²	102	116 Å²	116	69%	0.689	60%	0.6	S	S	*	*	T	Hydrogen-bonded Turn	trans	47.3	38.6	168.1	-73.1	0	0	0	0	115.8	L467 L468 S472	L467-C470 PolarHBondContact O-N 3.21Å; L468-C470 VanDerWaalsContact C-N 3.26Å; L468-C470 PolarHBondContact O-N 3.48Å; C470-S472 PolarHBondContact O-N 3.11Å
471	R	50.4	Low	54.5	Low	227 Å²	227	121.3 Å²	121.3	86%	0.857	64%	0.635	S	S	*	*			trans	-72.4	83.3	166.5	-106	-168.9	174.5	-156.7	-2.9	109.7	Q469 R473	Q469-R471 VanDerWaalsContact C-N 3.26Å; Q469-R471 PolarHBondContact O-N 3.05Å; R471-R473 VanDerWaalsContact C-N 3.3Å; R471-R473 PolarHBondContact O-N 3.15Å
472	S	43.2	Very low	52.8	Low	110 Å²	110	128.2 Å²	128.2	77%	0.769	67%	0.669	S	S	*	*			trans	-57.9	84.8	175.2	45.3	0	0	0	0	111.4	C470 L474	C470-S472 PolarHBondContact O-N 3.11Å; S472-L474 PolarHBondContact O-N 3Å
473	R	47.3	Very low	51.3	Low	238 Å²	238	131.4 Å²	131.4	90%	0.898	68%	0.684	S	S	*	*			trans	-71.5	70.1	165.3	-69.5	-166.1	-177	-141.6	3.4	110	R471	R471-R473 VanDerWaalsContact C-N 3.3Å; R471-R473 PolarHBondContact O-N 3.15Å
474	L	44.4	Very low	49.6	Very low	165 Å²	165	135.3 Å²	135.3	86%	0.864	71%	0.714	S	S	*	*			trans	-54	137.8	154.2	-137.4	73.5	0	0	0	107.4	S472 R476	S472-L474 PolarHBondContact O-N 3Å; L474-R476 PolarHBondContact O-N 3.03Å; L474-R476 VanDerWaalsContact O-N 3.14Å
475	G	45.3	Very low	48	Very low	71 Å²	71	139.6 Å²	139.6	73%	0.732	74%	0.743	S	S	*	*			trans	-69.6	112.8	-151.5	0	0	0	0	0	114.7	R477	G475-R477 PolarHBondContact O-N 3.37Å
476	R	38.3	Very low	46.4	Very low	252 Å²	252	139 Å²	139	95%	0.951	76%	0.755	S	S	*	*			trans	-75.2	72.8	155	-160.2	178.2	-163	-161	4.2	109.3	L474	L474-R476 PolarHBondContact O-N 3.03Å; L474-R476 VanDerWaalsContact O-N 3.14Å
477	R	37.7	Very low	44.6	Very low	238 Å²	238	141.9 Å²	141.9	90%	0.898	78%	0.775	S	S	*	*	P	Polyproline II helix	trans	-60.7	135	163.2	-165.5	176.1	-171.7	173.9	1.4	106.9	G475	G475-R477 PolarHBondContact O-N 3.37Å
478	G	42.9	Very low	42.9	Very low	71 Å²	71	147.4 Å²	147.4	73%	0.732	80%	0.799	S	S	*	*	P	Polyproline II helix	trans	-71.6	131.9	-171.9	0	0	0	0	0	112.7
479	S	32.1	Very low	41.2	Very low	114 Å²	114	146.7 Å²	146.7	80%	0.797	80%	0.8	S	S	*	*	P	Polyproline II helix	trans	-101.3	144	144.4	54.6	0	0	0	0	107.8
480	L	38.6	Very low	39.1	Very low	162 Å²	162	145 Å²	145	85%	0.848	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-74.9	164.6	174.6	-87.1	92.6	0	0	0	110.9
481	P	41.6	Very low	38.1	Very low	117 Å²	117	146.6 Å²	146.6	76%	0.76	81%	0.81	S	S	*	*	P	Polyproline II helix	trans	-71.2	132.2	164.9	31	-33.3	0	0	0	110.1
482	D	34.1	Very low	37.3	Very low	173 Å²	173	141.6 Å²	141.6	93%	0.925	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-83.2	118.9	154.1	-92.5	-47	0	0	0	107.6
483	D	35.6	Very low	36.9	Very low	134 Å²	134	144.3 Å²	144.3	72%	0.717	80%	0.803	S	S	*	*			trans	-151.1	126.4	164.5	-150.6	-28	0	0	0	110.8
484	S	36.4	Very low	36.3	Very low	109 Å²	109	138 Å²	138	76%	0.762	79%	0.788	S	S	*	*			trans	45.4	106.8	157.9	-60.1	0	0	0	0	119.5
485	T	35.6	Very low	35.7	Very low	139 Å²	139	137 Å²	137	85%	0.853	78%	0.783	S	S	*	*			trans	-118.9	138.2	164.4	-65.6	0	0	0	0	111.7
486	A	35.1	Very low	35.2	Very low	90 Å²	90	140.6 Å²	140.6	74%	0.744	79%	0.785	S	S	*	*			trans	62.5	96.4	166	0	0	0	0	0	118.9
487	T	33	Very low	35	Very low	133 Å²	133	142.7 Å²	142.7	82%	0.816	80%	0.795	S	S	*	*			trans	-58.8	134.1	147.6	-50.7	0	0	0	0	110.3
488	H	33.8	Very low	34.8	Very low	181 Å²	181	137.9 Å²	137.9	84%	0.838	79%	0.789	S	S	*	*			trans	-145.5	159	152.6	-119.4	-86.2	0	0	0	111.6
489	T	33.7	Very low	34.4	Very low	115 Å²	115	141.4 Å²	141.4	71%	0.706	79%	0.792	S	S	*	*			trans	-101.8	145.8	-155.9	50.5	0	0	0	0	115.7
490	S	29	Very low	34.5	Very low	103 Å²	103	142.9 Å²	142.9	72%	0.72	79%	0.792	S	S	*	*			trans	64.1	116.7	147.7	-166.1	0	0	0	0	118.8
491	T	31.3	Very low	34.3	Very low	136 Å²	136	141.8 Å²	141.8	83%	0.834	79%	0.789	S	S	*	*				-164.7	165.6	102.3	17.4	0	0	0	0	112.5
492	T	34.8	Very low	33.9	Very low	122 Å²	122	143.4 Å²	143.4	75%	0.748	79%	0.791	S	S	*	*			trans	-73.2	159.6	-176.3	43.1	0	0	0	0	116.1
493	K	33.4	Very low	33.8	Very low	167 Å²	167	141.4 Å²	141.4	73%	0.726	78%	0.782	S	S	*	*			trans	99.3	133.9	136.6	-91.8	169.5	152.9	-91.3	0	121.5
494	D	34.8	Very low	33.7	Very low	107 Å²	107	141.9 Å²	141.9	57%	0.572	79%	0.786	S	S	*	*			trans	67.7	100.1	136.5	-56	-17.5	0	0	0	122.1
495	N	33.8	Very low	33.5	Very low	143 Å²	143	144.5 Å²	144.5	77%	0.765	79%	0.788	S	S	*	*				80.8	147.8	123	-68.7	-38.1	0	0	0	123.9
496	L	33.4	Very low	33.3	Very low	146 Å²	146	144.9 Å²	144.9	76%	0.764	78%	0.783	S	S	*	*			trans	84.9	125	147.8	-79.2	154.8	0	0	0	121.2
497	Y	33.8	Very low	33.2	Very low	296 Å²	296	149.9 Å²	149.9	100%	1.161	79%	0.786	S	S	*	*			trans	64.5	0	167.3	-74.7	-73.2	0	0	0	119

Retrieved 497 of 497 residues in 175 ms (Link to these results)

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