A0A087Y1D8_POEFO Loading...

RNA helicase

AlphaFold DB , UniProt , Accession A0A087Y1D8, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 681 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M36.4Very low79.3Confident224 Ų22478.5 Ų78.5100%1.10341%0.407SS*.  0119.20-78.6165.2108.300107.1
2G42.1Very low80.8Confident73 Ų7374.3 Ų74.375%0.75338%0.384SS*.  trans-71.9141.5176.500000110.5F4G2-F4 PolarHBondContact O-N 3.03Å
3E55.3Low82.1Confident180 Ų18068.8 Ų68.884%0.84136%0.356SS*.  trans-59.7127.4179.4-158.2167.9-168.900110.3E5E3-E5 VanDerWaalsContact C-N 3.28Å; E3-E5 PolarHBondContact O-N 3.34Å
4F77.6Confident83.2Confident26 Ų2664 Ų6411%0.11433%0.331CS..  trans-76.882.2177.8-178.6-102.1000109.5G2 V38 Y39 Y74G2-F4 PolarHBondContact O-N 3.03Å; F4-V38 HydrophobicContact CE2-CB 4.43Å; F4-V38 HydrophobicContact CE2-CG1 3.92Å; F4-V38 HydrophobicContact CZ-CB 4.02Å; F4-V38 HydrophobicContact CZ-CG1 3.65Å; F4-Y39 AromaticContact CD1-CD2 3.96Å; F4-Y39 HydrophobicContact CD1-CD2 3.96Å; F4-Y39 AromaticContact CE1-CD2 3.5Å; F4-Y39 HydrophobicContact CE1-CD2 3.5Å; F4-Y39 VanDerWaalsContact CE1-CD2 3.5Å; F4-Y39 AromaticContact CE1-CG 4Å; F4-Y39 HydrophobicContact CE1-CG 4Å; F4-Y74 HydrophobicContact CB-CD1 4.26Å; F4-Y74 AromaticContact CD2-CD1 3.28Å; F4-Y74 HydrophobicContact CD2-CD1 3.28Å; F4-Y74 AromaticContact CD2-CD2 3.75Å; F4-Y74 HydrophobicContact CD2-CD2 3.75Å; F4-Y74 AromaticContact CD2-CE1 3.71Å; F4-Y74 HydrophobicContact CD2-CE1 3.71Å; F4-Y74 HydrophobicContact CD2-CE2 4.23Å; F4-Y74 AromaticContact CD2-CG 3.33Å; F4-Y74 HydrophobicContact CD2-CG 3.33Å; F4-Y74 AromaticContact CE2-CD1 3.92Å; F4-Y74 HydrophobicContact CE2-CD1 3.92Å; F4-Y74 AromaticContact CE2-CD2 3.49Å; F4-Y74 HydrophobicContact CE2-CD2 3.49Å; F4-Y74 VanDerWaalsContact CE2-CD2 3.49Å; F4-Y74 HydrophobicContact CE2-CE1 4.42Å; F4-Y74 HydrophobicContact CE2-CE2 4.14Å; F4-Y74 AromaticContact CE2-CG 3.45Å; F4-Y74 HydrophobicContact CE2-CG 3.45Å; F4-Y74 VanDerWaalsContact CE2-CG 3.45Å; F4-Y74 HydrophobicContact CG-CD1 4.13Å; F4-Y74 HydrophobicContact CG-CG 4.36Å
5E85.8Confident84.1Confident122 Ų12266.7 Ų66.757%0.5734%0.341SS*.  trans-107.8134-179.8-154.1-176.1177.100112.4E3 K11E3-E5 VanDerWaalsContact C-N 3.28Å; E3-E5 PolarHBondContact O-N 3.34Å; E5-K11 IonicContact OE1-NZ 3.74Å; E5-K11 PolarHBondContact OE1-NZ 2.92Å
6L93.4Very high85Confident5 Ų567.9 Ų67.93%0.02634%0.341CS..  trans-85.4146.4170.3-70.1-172.6000110.8Q10 K11 V14 R35 Y39L6-Q10 HydrophobicContact CB-CB 4.03Å; L6-Q10 HydrophobicContact CD1-CB 4.3Å; L6-Q10 HydrophobicContact CD2-CB 4.23Å; L6-Q10 HydrophobicContact CG-CB 4.43Å; L6-K11 HydrophobicContact CB-CG 3.71Å; L6-K11 HydrophobicContact CD1-CG 4.44Å; L6-K11 WeakPolarHBondContact O-CE 3.29Å; L6-K11 PolarHBondContact O-NZ 3.04Å; L6-V14 HydrophobicContact CD1-CG2 4.07Å; L6-R35 HydrophobicContact CD2-CG 3.82Å; L6-Y39 HydrophobicContact CD1-CD1 3.71Å; L6-Y39 HydrophobicContact CD1-CD2 3.73Å; L6-Y39 HydrophobicContact CD1-CE1 4.32Å; L6-Y39 HydrophobicContact CD1-CE2 4.35Å; L6-Y39 HydrophobicContact CD1-CG 3.41Å; L6-Y39 VanDerWaalsContact CD1-CG 3.41Å; L6-Y39 HydrophobicContact CD2-CG 4.46Å; L6-Y39 HydrophobicContact CG-CD2 3.75Å; L6-Y39 HydrophobicContact CG-CE2 4.46Å; L6-Y39 HydrophobicContact CG-CG 3.88Å
7R94.9Very high85.7Confident98 Ų9864.1 Ų64.137%0.3732%0.322SS..  trans-64.7159.8167.3-65.6178.2-172.3147.30.7111.1Y9 Q10 K11 E209R7-Y9 HydrophobicContact CB-CD1 3.93Å; R7-Y9 HydrophobicContact CB-CE1 3.67Å; R7-Y9 WeakPolarHBondContact CD-OH 3.49Å; R7-Y9 HydrophobicContact CG-CE1 4.18Å; R7-Y9 PolarHBondContact NH1-OH 2.91Å; R7-Y9 PolarHBondContact O-N 3.48Å; R7-Q10 HydrophobicContact CB-CB 4.45Å; R7-Q10 HydrophobicContact CB-CG 4.11Å; R7-Q10 WeakPolarHBondContact O-CA 3.43Å; R7-Q10 WeakPolarHBondContact O-CB 3.48Å; R7-Q10 PolarHBondContact O-N 3.49Å; R7-K11 PolarHBondContact O-N 3.47Å; R7-E209 WeakPolarHBondContact CB-OE1 3.23Å
8S96.6Very high86.4Confident41 Ų4164.6 Ų64.629%0.28733%0.325SS..Hα-helixtrans-63.4-42.9-173.6-30.30000111.8Q10 K11 E12 Y206 E209S8-Q10 PolarHBondContact O-N 3.17Å; S8-K11 WeakPolarHBondContact O-CB 3.38Å; S8-K11 PolarHBondContact O-N 3.17Å; S8-K11 VanDerWaalsContact O-N 3.17Å; S8-E12 PolarHBondContact O-N 3.08Å; S8-Y206 VanDerWaalsContact CB-CD1 3.48Å; S8-E209 WeakPolarHBondContact CB-OE2 3.45Å; S8-E209 PolarHBondContact N-OE1 3.08Å; S8-E209 PolarHBondContact N-OE2 3.13Å; S8-E209 PolarHBondContact OG-OE2 3.31Å
9Y96.8Very high86.9Confident0 Ų069.2 Ų69.20%034%0.343CS..Hα-helixtrans-63.5-28.5174.774-102.2000113R7 V13 L27 G31 E209 L210R7-Y9 HydrophobicContact CB-CD1 3.93Å; R7-Y9 HydrophobicContact CB-CE1 3.67Å; R7-Y9 WeakPolarHBondContact CD-OH 3.49Å; R7-Y9 HydrophobicContact CG-CE1 4.18Å; R7-Y9 PolarHBondContact NH1-OH 2.91Å; R7-Y9 PolarHBondContact O-N 3.48Å; Y9-V13 PolarHBondContact O-N 3.44Å; Y9-L27 HydrophobicContact CD2-CD1 4.29Å; Y9-L27 HydrophobicContact CD2-CD2 3.96Å; Y9-L27 HydrophobicContact CE2-CD1 4.06Å; Y9-L27 HydrophobicContact CE2-CD2 4.32Å; Y9-G31 VanDerWaalsContact CE2-O 3.25Å; Y9-G31 WeakPolarHBondContact CE2-O 3.47Å; Y9-G31 PolarHBondContact OH-O 2.77Å; Y9-E209 HydrophobicContact CD1-CG 4.22Å; Y9-L210 HydrophobicContact CD1-CB 4.16Å; Y9-L210 HydrophobicContact CD1-CD1 4.33Å; Y9-L210 HydrophobicContact CD2-CD1 3.96Å; Y9-L210 HydrophobicContact CE1-CD1 4.07Å; Y9-L210 HydrophobicContact CE2-CD1 3.7Å; Y9-L210 HydrophobicContact CG-CB 4.25Å; Y9-L210 HydrophobicContact CG-CD1 4.29Å
10Q97.1Very high87.4Confident7 Ų768.2 Ų68.23%0.03335%0.351CS..Hα-helixtrans-75.2-40.5175.5-65.5176.1-45.200110.6L6 R7 S8 E12 V13 V14 G31 G32L6-Q10 HydrophobicContact CB-CB 4.03Å; L6-Q10 HydrophobicContact CD1-CB 4.3Å; L6-Q10 HydrophobicContact CD2-CB 4.23Å; L6-Q10 HydrophobicContact CG-CB 4.43Å; R7-Q10 HydrophobicContact CB-CB 4.45Å; R7-Q10 HydrophobicContact CB-CG 4.11Å; R7-Q10 WeakPolarHBondContact O-CA 3.43Å; R7-Q10 WeakPolarHBondContact O-CB 3.48Å; R7-Q10 PolarHBondContact O-N 3.49Å; S8-Q10 PolarHBondContact O-N 3.17Å; Q10-E12 VanDerWaalsContact C-N 3.32Å; Q10-V13 WeakPolarHBondContact O-CG2 3.45Å; Q10-V13 PolarHBondContact O-N 3.26Å; Q10-V14 WeakPolarHBondContact O-CG1 3.45Å; Q10-V14 WeakPolarHBondContact O-CG2 3.36Å; Q10-V14 PolarHBondContact O-N 3.45Å; Q10-G31 PolarHBondContact NE2-O 3.46Å; Q10-G32 PolarHBondContact NE2-O 3.1Å
11K96.5Very high87.9Confident87 Ų8767.9 Ų67.938%0.37835%0.348SS..Hα-helixtrans-57.5-46.6173.5-69.6173.4176.6160.80110.1E5 L6 R7 S8 V13 V14 E15E5-K11 IonicContact OE1-NZ 3.74Å; E5-K11 PolarHBondContact OE1-NZ 2.92Å; L6-K11 HydrophobicContact CB-CG 3.71Å; L6-K11 HydrophobicContact CD1-CG 4.44Å; L6-K11 WeakPolarHBondContact O-CE 3.29Å; L6-K11 PolarHBondContact O-NZ 3.04Å; R7-K11 PolarHBondContact O-N 3.47Å; S8-K11 WeakPolarHBondContact O-CB 3.38Å; S8-K11 PolarHBondContact O-N 3.17Å; S8-K11 VanDerWaalsContact O-N 3.17Å; K11-V13 PolarHBondContact O-N 3.34Å; K11-V14 VanDerWaalsContact O-CG2 3.24Å; K11-V14 WeakPolarHBondContact O-CG2 3.48Å; K11-V14 PolarHBondContact O-N 3.05Å; K11-E15 VanDerWaalsContact O-CG 3.32Å; K11-E15 WeakPolarHBondContact O-CG 3.3Å
12E97.3Very high90.8Very high29 Ų2958.6 Ų58.614%0.13630%0.302CS..Hα-helixtrans-56.7-48.7178.7-177-178.5-168.200112.7S8 Q10 V14 T203 K204 N205 Y206S8-E12 PolarHBondContact O-N 3.08Å; Q10-E12 VanDerWaalsContact C-N 3.32Å; E12-V14 VanDerWaalsContact C-N 3.34Å; E12-V14 PolarHBondContact O-N 3.14Å; E12-T203 VanDerWaalsContact OE2-CA 3.29Å; E12-T203 WeakPolarHBondContact OE2-CA 3.49Å; E12-T203 WeakPolarHBondContact OE2-CB 2.97Å; E12-T203 PolarHBondContact OE2-OG1 3.43Å; E12-K204 PolarHBondContact OE1-N 3.2Å; E12-K204 PolarHBondContact OE2-N 3.01Å; E12-N205 PolarHBondContact OE1-N 3.18Å; E12-N205 VanDerWaalsContact OE1-N 3.09Å; E12-N205 PolarHBondContact OE1-ND2 3.46Å; E12-N205 PolarHBondContact OE2-N 2.66Å; E12-Y206 HydrophobicContact CB-CD2 4.1Å; E12-Y206 HydrophobicContact CB-CE2 4.31Å; E12-Y206 WeakPolarHBondContact OE2-CD2 3.35Å
13V97.1Very high93.5Very high2 Ų255.1 Ų55.11%0.01227%0.267CS..Hα-helixtrans-76.4-17.8-174.2-61.40000114.2Y9 Q10 K11 I25 L27 V201Y9-V13 PolarHBondContact O-N 3.44Å; Q10-V13 WeakPolarHBondContact O-CG2 3.45Å; Q10-V13 PolarHBondContact O-N 3.26Å; K11-V13 PolarHBondContact O-N 3.34Å; V13-I25 HydrophobicContact CB-CG2 4.25Å; V13-I25 HydrophobicContact CG2-CD1 4.42Å; V13-I25 HydrophobicContact CG2-CG2 3.81Å; V13-L27 HydrophobicContact CG1-CD2 4.09Å; V13-L27 HydrophobicContact CG2-CD1 4.03Å; V13-L27 HydrophobicContact CG2-CD2 4.46Å; V13-L27 HydrophobicContact CG2-CG 4.37Å; V13-V201 HydrophobicContact CB-CG2 4.11Å; V13-V201 WeakPolarHBondContact O-CG2 3.06Å
14V97.7Very high95.6Very high2 Ų246.6 Ų46.61%0.01223%0.227CC..Hα-helixtrans-88.5-14.1178.2-61.50000113.3L6 Q10 K11 E12 R16 A17 L18 I25 A36 Y39 V40L6-V14 HydrophobicContact CD1-CG2 4.07Å; Q10-V14 WeakPolarHBondContact O-CG1 3.45Å; Q10-V14 WeakPolarHBondContact O-CG2 3.36Å; Q10-V14 PolarHBondContact O-N 3.45Å; K11-V14 VanDerWaalsContact O-CG2 3.24Å; K11-V14 WeakPolarHBondContact O-CG2 3.48Å; K11-V14 PolarHBondContact O-N 3.05Å; E12-V14 VanDerWaalsContact C-N 3.34Å; E12-V14 PolarHBondContact O-N 3.14Å; V14-R16 VanDerWaalsContact C-N 3.3Å; V14-R16 PolarHBondContact O-N 3.08Å; V14-R16 VanDerWaalsContact O-N 3.16Å; V14-A17 WeakPolarHBondContact O-CA 3.49Å; V14-A17 WeakPolarHBondContact O-CB 3.2Å; V14-A17 PolarHBondContact O-N 2.96Å; V14-L18 HydrophobicContact CB-CG 4.45Å; V14-L18 HydrophobicContact CG2-CD1 3.87Å; V14-L18 HydrophobicContact CG2-CG 4.33Å; V14-L18 WeakPolarHBondContact O-CG 3.42Å; V14-L18 PolarHBondContact O-N 2.78Å; V14-I25 HydrophobicContact CG1-CD1 3.91Å; V14-A36 HydrophobicContact CG1-CB 3.75Å; V14-Y39 HydrophobicContact CG2-CD1 4.3Å; V14-V40 HydrophobicContact CB-CG2 3.76Å; V14-V40 HydrophobicContact CG1-CG2 3.72Å
15E97.3Very high96.6Very high104 Ų10445.4 Ų45.449%0.48622%0.222SC..Hα-helixtrans-53.6-42.8-170.6-66.9-175.1175.900114K11 L18 K19K11-E15 VanDerWaalsContact O-CG 3.32Å; K11-E15 WeakPolarHBondContact O-CG 3.3Å; E15-L18 PolarHBondContact O-N 3Å; E15-K19 WeakPolarHBondContact O-CG 3.46Å; E15-K19 PolarHBondContact O-N 3.34Å
16R97.6Very high97.1Very high87 Ų8742.4 Ų42.433%0.32821%0.205SC..Hα-helixtrans-69.5-38.7178.7-67.8-173.474.4173.12.2112V14 L18 K19 E21 V23V14-R16 VanDerWaalsContact C-N 3.3Å; V14-R16 PolarHBondContact O-N 3.08Å; V14-R16 VanDerWaalsContact O-N 3.16Å; R16-L18 VanDerWaalsContact C-N 3.3Å; R16-L18 PolarHBondContact O-N 3.25Å; R16-K19 WeakPolarHBondContact O-CB 3.21Å; R16-K19 PolarHBondContact O-N 3.49Å; R16-K19 VanDerWaalsContact O-N 3.12Å; R16-E21 HydrophobicContact CB-CB 4.35Å; R16-E21 IonicContact CZ-OE2 3.06Å; R16-E21 VanDerWaalsContact CZ-OE2 3.24Å; R16-E21 IonicContact NE-OE1 3.48Å; R16-E21 PolarHBondContact NE-OE1 2.96Å; R16-E21 IonicContact NE-OE2 3.82Å; R16-E21 PolarHBondContact NE-OE2 3.29Å; R16-E21 IonicContact NH2-OE2 3.42Å; R16-E21 PolarHBondContact NH2-OE2 3.44Å; R16-E21 WeakPolarHBondContact O-CB 3.26Å; R16-E21 PolarHBondContact O-N 3.11Å; R16-E21 VanDerWaalsContact O-N 3.14Å; R16-V23 HydrophobicContact CB-CG2 3.68Å
17A97.9Very high97.2Very high3 Ų342.2 Ų42.23%0.02520%0.204CC..Hα-helixtrans-64.5-37.7175.700000111V14 K19 G20 V23 V40 Q166 L168V14-A17 WeakPolarHBondContact O-CA 3.49Å; V14-A17 WeakPolarHBondContact O-CB 3.2Å; V14-A17 PolarHBondContact O-N 2.96Å; A17-K19 PolarHBondContact O-N 3.11Å; A17-G20 PolarHBondContact O-N 2.99Å; A17-V23 HydrophobicContact CB-CB 4.33Å; A17-V23 HydrophobicContact CB-CG2 4.28Å; A17-V40 HydrophobicContact CB-CG1 4.04Å; A17-V40 HydrophobicContact CB-CG2 4.01Å; A17-Q166 PolarHBondContact O-NE2 2.97Å; A17-L168 HydrophobicContact CB-CD1 4.1Å
18L97.6Very high97.1Very high72 Ų7239.4 Ų39.438%0.37720%0.199SC..Hα-helixtrans-66.1-21.3175.1-63174.5000113.7V14 E15 R16 G20 Y39 V40 R43V14-L18 HydrophobicContact CB-CG 4.45Å; V14-L18 HydrophobicContact CG2-CD1 3.87Å; V14-L18 HydrophobicContact CG2-CG 4.33Å; V14-L18 WeakPolarHBondContact O-CG 3.42Å; V14-L18 PolarHBondContact O-N 2.78Å; E15-L18 PolarHBondContact O-N 3Å; R16-L18 VanDerWaalsContact C-N 3.3Å; R16-L18 PolarHBondContact O-N 3.25Å; L18-G20 VanDerWaalsContact C-N 3.26Å; L18-Y39 HydrophobicContact CD1-CD1 4.42Å; L18-Y39 HydrophobicContact CD1-CE1 3.73Å; L18-Y39 HydrophobicContact CD2-CD1 4.13Å; L18-Y39 HydrophobicContact CD2-CE1 3.91Å; L18-Y39 HydrophobicContact CG-CE1 4.42Å; L18-V40 HydrophobicContact CD2-CG2 4.36Å; L18-R43 HydrophobicContact CD2-CB 3.61Å; L18-R43 HydrophobicContact CD2-CG 3.71Å
19K97.1Very high96.6Very high153 Ų15338.1 Ų38.167%0.66519%0.189SC*.THydrogen-bonded Turntrans-84.93.4172.9-66.1170.6-173.71730113E15 R16 A17E15-K19 WeakPolarHBondContact O-CG 3.46Å; E15-K19 PolarHBondContact O-N 3.34Å; R16-K19 WeakPolarHBondContact O-CB 3.21Å; R16-K19 PolarHBondContact O-N 3.49Å; R16-K19 VanDerWaalsContact O-N 3.12Å; A17-K19 PolarHBondContact O-N 3.11Å
20G95.9Very high96.1Very high48 Ų4839.5 Ų39.550%0.49520%0.204SC..THydrogen-bonded Turntrans83.710-178.500000114.5A17 L18 Q166A17-G20 PolarHBondContact O-N 2.99Å; L18-G20 VanDerWaalsContact C-N 3.26Å; G20-Q166 VanDerWaalsContact C-NE2 3.33Å
21E97.6Very high95.7Very high62 Ų6239.2 Ų39.229%0.2920%0.202SC..  trans-79148.7176.5-58.3-176.1-112.600111.6R16 V23 Q166R16-E21 HydrophobicContact CB-CB 4.35Å; R16-E21 IonicContact CZ-OE2 3.06Å; R16-E21 VanDerWaalsContact CZ-OE2 3.24Å; R16-E21 IonicContact NE-OE1 3.48Å; R16-E21 PolarHBondContact NE-OE1 2.96Å; R16-E21 IonicContact NE-OE2 3.82Å; R16-E21 PolarHBondContact NE-OE2 3.29Å; R16-E21 IonicContact NH2-OE2 3.42Å; R16-E21 PolarHBondContact NH2-OE2 3.44Å; R16-E21 WeakPolarHBondContact O-CB 3.26Å; R16-E21 PolarHBondContact O-N 3.11Å; R16-E21 VanDerWaalsContact O-N 3.14Å; E21-V23 HydrophobicContact CB-CG2 4.24Å; E21-Q166 PolarHBondContact O-NE2 3.25Å
22N98.5Very high95.5Very high29 Ų2936.2 Ų36.216%0.15520%0.196CC..  trans-76.2123172.1-71.8-9.3000110.5Y153 Q166 I167 D197 S198 V199N22-Y153 PolarHBondContact ND2-OH 3.27Å; N22-Y153 VanDerWaalsContact ND2-OH 3.09Å; N22-Q166 WeakPolarHBondContact OD1-CA 3.31Å; N22-I167 WeakPolarHBondContact CA-O 3.38Å; N22-I167 HydrophobicContact CB-CB 4.23Å; N22-I167 PolarHBondContact OD1-N 3.49Å; N22-D197 WeakPolarHBondContact CB-O 3.32Å; N22-D197 PolarHBondContact ND2-O 2.89Å; N22-D197 VanDerWaalsContact ND2-O 3.1Å; N22-D197 PolarHBondContact ND2-OD2 3.32Å; N22-S198 WeakPolarHBondContact O-CA 3.4Å; N22-V199 VanDerWaalsContact O-CG2 3.3Å; N22-V199 WeakPolarHBondContact O-CG2 3.44Å; N22-V199 PolarHBondContact O-N 3.02Å
23V98.4Very high95.3Very high0 Ų035.6 Ų35.60%019%0.193CC..EExtended strand (participates in β ladder)trans-137.3140.9-166.7175.90000112.1R16 A17 E21 I25 I167 L168 G169 V199 V201R16-V23 HydrophobicContact CB-CG2 3.68Å; A17-V23 HydrophobicContact CB-CB 4.33Å; A17-V23 HydrophobicContact CB-CG2 4.28Å; E21-V23 HydrophobicContact CB-CG2 4.24Å; V23-I25 HydrophobicContact CG1-CG1 4.17Å; V23-I167 PolarHBondContact N-O 3.11Å; V23-L168 HydrophobicContact CB-CD1 4.41Å; V23-L168 CarbonylContact O-C 3.27Å; V23-L168 WeakPolarHBondContact O-CA 3.35Å; V23-G169 PolarHBondContact O-N 2.98Å; V23-V199 CarbonylContact C-O 3.56Å; V23-V199 WeakPolarHBondContact CA-O 3.18Å; V23-V199 HydrophobicContact CG2-CG2 4.03Å; V23-V201 HydrophobicContact CG1-CB 4.19Å; V23-V201 HydrophobicContact CG1-CG1 3.84Å; V23-V201 HydrophobicContact CG1-CG2 3.3Å
24I98.8Very high95.2Very high2 Ų236.8 Ų36.81%0.0120%0.2CC..EExtended strand (participates in β ladder)trans-103.4112.7163.3-61.9163000108.2W26 G169 T171 I192 L196 V199 I200 V201I24-W26 PolarHBondContact O-N 3.3Å; I24-G169 CarbonylContact C-O 3.6Å; I24-G169 WeakPolarHBondContact CA-O 3.49Å; I24-T171 HydrophobicContact CG2-CG2 3.86Å; I24-I192 HydrophobicContact CD1-CG2 4.13Å; I24-L196 HydrophobicContact CD1-CB 4.15Å; I24-L196 HydrophobicContact CD1-CD1 3.64Å; I24-L196 HydrophobicContact CG1-CB 4.39Å; I24-L196 HydrophobicContact CG1-CD1 3.83Å; I24-V199 PolarHBondContact N-O 3.44Å; I24-I200 HydrophobicContact CB-CB 4.3Å; I24-I200 HydrophobicContact CB-CG1 4.22Å; I24-I200 HydrophobicContact CG2-CD1 4.26Å; I24-I200 HydrophobicContact CG2-CG1 4.11Å; I24-I200 WeakPolarHBondContact O-CA 3.42Å; I24-V201 WeakPolarHBondContact O-CG2 3.13Å; I24-V201 PolarHBondContact O-N 2.82Å
25I98.5Very high95Very high0 Ų039.1 Ų39.10%021%0.209CC..EExtended strand (participates in β ladder)trans-80114.5172.4-64.5179.5000109.1V13 V14 V23 L27 A36 L168 G169 L170 T171 V201V13-I25 HydrophobicContact CB-CG2 4.25Å; V13-I25 HydrophobicContact CG2-CD1 4.42Å; V13-I25 HydrophobicContact CG2-CG2 3.81Å; V14-I25 HydrophobicContact CG1-CD1 3.91Å; V23-I25 HydrophobicContact CG1-CG1 4.17Å; I25-L27 HydrophobicContact CG2-CD1 3.91Å; I25-L27 HydrophobicContact CG2-CG 3.82Å; I25-A36 HydrophobicContact CD1-CB 4.4Å; I25-L168 HydrophobicContact CD1-CD1 3.79Å; I25-L168 HydrophobicContact CG1-CD1 3.95Å; I25-G169 PolarHBondContact N-O 3.15Å; I25-L170 HydrophobicContact CB-CD2 4.13Å; I25-L170 HydrophobicContact CD1-CD2 4.21Å; I25-T171 PolarHBondContact O-N 3.03Å; I25-T171 VanDerWaalsContact O-N 3.1Å; I25-V201 HydrophobicContact CG1-CG2 4.17Å
26W97.5Very high95Very high59 Ų5934.2 Ų34.222%0.22319%0.186CC..EExtended strand (participates in β ladder)trans-102.1104.4173.3179.543.2000110.8I24 T171 A172 I200 V201 I509I24-W26 PolarHBondContact O-N 3.3Å; W26-T171 WeakPolarHBondContact CA-O 3.36Å; W26-A172 VanDerWaalsContact CD1-O 3.27Å; W26-A172 PolarHBondContact NE1-O 2.89Å; W26-I200 HydrophobicContact CB-CD1 4.06Å; W26-I200 HydrophobicContact CB-CG1 4.01Å; W26-I200 HydrophobicContact CG-CD1 4.47Å; W26-V201 WeakPolarHBondContact CB-O 3.45Å; W26-V201 PolarHBondContact N-O 3.22Å; W26-I509 HydrophobicContact CD2-CD1 3.5Å; W26-I509 HydrophobicContact CE3-CB 4.24Å; W26-I509 HydrophobicContact CE3-CD1 3.5Å; W26-I509 VanDerWaalsContact CE3-CD1 3.5Å; W26-I509 HydrophobicContact CE3-CG1 4.44Å; W26-I509 HydrophobicContact CE3-CG2 3.61Å; W26-I509 HydrophobicContact CG-CD1 4.21Å; W26-I509 HydrophobicContact CH2-CD1 3.76Å; W26-I509 HydrophobicContact CZ2-CD1 3.73Å; W26-I509 HydrophobicContact CZ3-CB 3.99Å; W26-I509 HydrophobicContact CZ3-CD1 3.64Å; W26-I509 HydrophobicContact CZ3-CG1 4.44Å; W26-I509 HydrophobicContact CZ3-CG2 3.69Å
27L95.4Very high94.9Very high1 Ų130.1 Ų30.11%0.00517%0.17CC..  trans-138.2146.9174.8-66.7176000109.8Y9 V13 I25 K33 T171 A172 T203Y9-L27 HydrophobicContact CD2-CD1 4.29Å; Y9-L27 HydrophobicContact CD2-CD2 3.96Å; Y9-L27 HydrophobicContact CE2-CD1 4.06Å; Y9-L27 HydrophobicContact CE2-CD2 4.32Å; V13-L27 HydrophobicContact CG1-CD2 4.09Å; V13-L27 HydrophobicContact CG2-CD1 4.03Å; V13-L27 HydrophobicContact CG2-CD2 4.46Å; V13-L27 HydrophobicContact CG2-CG 4.37Å; I25-L27 HydrophobicContact CG2-CD1 3.91Å; I25-L27 HydrophobicContact CG2-CG 3.82Å; L27-K33 HydrophobicContact CB-CD 4.28Å; L27-K33 HydrophobicContact CB-CG 3.77Å; L27-K33 HydrophobicContact CD1-CG 4.22Å; L27-K33 HydrophobicContact CG-CG 4.46Å; L27-K33 WeakPolarHBondContact O-CD 3.38Å; L27-K33 PolarHBondContact O-NZ 3.4Å; L27-T171 PolarHBondContact N-O 3.32Å; L27-A172 VanDerWaalsContact O-CA 3.25Å; L27-A172 WeakPolarHBondContact O-CA 3.23Å; L27-T203 HydrophobicContact CD2-CG2 4.43Å
28P91.3Very high94.9Very high39 Ų3930 Ų3025%0.25317%0.169SC..  trans-58.3161.9179.726-35.5000112.9G30 G31 K33 L210 V214P28-G30 PolarHBondContact O-N 2.98Å; P28-G31 PolarHBondContact O-N 2.97Å; P28-K33 PolarHBondContact O-NZ 2.85Å; P28-L210 HydrophobicContact CG-CD1 3.85Å; P28-L210 HydrophobicContact CG-CD2 3.94Å; P28-L210 HydrophobicContact CG-CG 4.14Å; P28-V214 HydrophobicContact CB-CG1 4.37Å; P28-V214 HydrophobicContact CG-CG1 4.2Å
29T87.4Confident94.9Very high14 Ų1428.4 Ų28.49%0.08616%0.159CC..THydrogen-bonded Turntrans-59.3133.5171.8-55.40000109.5G31 A172 V214 Q469 G472T29-G31 VanDerWaalsContact C-N 3.29Å; T29-G31 PolarHBondContact O-N 3.33Å; T29-A172 WeakPolarHBondContact OG1-CB 3.25Å; T29-V214 VanDerWaalsContact O-CG1 3.23Å; T29-V214 WeakPolarHBondContact O-CG1 3.24Å; T29-Q469 PolarHBondContact OG1-OE1 2.89Å; T29-G472 VanDerWaalsContact CG2-O 3.27Å; T29-G472 WeakPolarHBondContact CG2-O 3.3Å
30G85.4Confident95Very high30 Ų3021.2 Ų21.231%0.30913%0.127SC..THydrogen-bonded Turntrans84.5-9.8-170.600000115P28 G32P28-G30 PolarHBondContact O-N 2.98Å; G30-G32 PolarHBondContact O-N 3.33Å
31G89.6Confident95.1Very high0 Ų018.9 Ų18.90%010%0.104CC..SBendtrans-680.7177.600000115.8Y9 Q10 P28 T29Y9-G31 VanDerWaalsContact CE2-O 3.25Å; Y9-G31 WeakPolarHBondContact CE2-O 3.47Å; Y9-G31 PolarHBondContact OH-O 2.77Å; Q10-G31 PolarHBondContact NE2-O 3.46Å; P28-G31 PolarHBondContact O-N 2.97Å; T29-G31 VanDerWaalsContact C-N 3.29Å; T29-G31 PolarHBondContact O-N 3.33Å
32G91.3Very high95.1Very high24 Ų2418.4 Ų18.425%0.24710%0.099CC..  trans72.540.1178.200000113.9Q10 G30 T34 R35 A36Q10-G32 PolarHBondContact NE2-O 3.1Å; G30-G32 PolarHBondContact O-N 3.33Å; G32-T34 VanDerWaalsContact C-N 3.34Å; G32-T34 PolarHBondContact O-N 3.35Å; G32-R35 WeakPolarHBondContact O-CB 3.45Å; G32-R35 PolarHBondContact O-N 2.97Å; G32-A36 PolarHBondContact O-N 3.04Å; G32-A36 VanDerWaalsContact O-N 3.12Å
33K94.4Very high95Very high17 Ų1721.8 Ų21.87%0.07411%0.11CC..Hα-helixtrans-55.9-45.8175.5-70.9-175.8-72.4-76.80112.5L27 P28 R35 A36 A37 L170 T171L27-K33 HydrophobicContact CB-CD 4.28Å; L27-K33 HydrophobicContact CB-CG 3.77Å; L27-K33 HydrophobicContact CD1-CG 4.22Å; L27-K33 HydrophobicContact CG-CG 4.46Å; L27-K33 WeakPolarHBondContact O-CD 3.38Å; L27-K33 PolarHBondContact O-NZ 3.4Å; P28-K33 PolarHBondContact O-NZ 2.85Å; K33-R35 VanDerWaalsContact C-N 3.33Å; K33-R35 PolarHBondContact O-N 3.41Å; K33-A36 WeakPolarHBondContact O-CB 3.33Å; K33-A36 PolarHBondContact O-N 3.39Å; K33-A37 PolarHBondContact O-N 2.87Å; K33-L170 HydrophobicContact CB-CB 4.39Å; K33-L170 HydrophobicContact CD-CB 4.4Å; K33-T171 WeakPolarHBondContact CD-O 3.38Å
34T93.4Very high95Very high26 Ų2622.7 Ų22.716%0.1611%0.114CC..Hα-helixtrans-62-41.7179.4-43.20000111.4G32 A36 A37 V38 H66 E70 F71G32-T34 VanDerWaalsContact C-N 3.34Å; G32-T34 PolarHBondContact O-N 3.35Å; T34-A36 PolarHBondContact O-N 3.36Å; T34-A37 WeakPolarHBondContact O-CA 3.27Å; T34-A37 WeakPolarHBondContact O-CB 3.31Å; T34-A37 PolarHBondContact O-N 2.74Å; T34-A37 VanDerWaalsContact O-N 3.11Å; T34-V38 WeakPolarHBondContact O-CG2 3.44Å; T34-V38 PolarHBondContact O-N 2.9Å; T34-H66 HydrophobicContact CG2-CB 4.47Å; T34-E70 HydrophobicContact CG2-CB 3.9Å; T34-E70 HydrophobicContact CG2-CG 3.75Å; T34-F71 HydrophobicContact CG2-CE2 4.14Å
35R94.3Very high94.9Very high52 Ų5223.3 Ų23.320%0.19612%0.117CC..Hα-helixtrans-59.6-44.2174.8-178.25856.9111.76.4112.5L6 G32 K33 A37 V38 Y39 E70 Y74L6-R35 HydrophobicContact CD2-CG 3.82Å; G32-R35 WeakPolarHBondContact O-CB 3.45Å; G32-R35 PolarHBondContact O-N 2.97Å; K33-R35 VanDerWaalsContact C-N 3.33Å; K33-R35 PolarHBondContact O-N 3.41Å; R35-A37 VanDerWaalsContact C-N 3.3Å; R35-A37 PolarHBondContact O-N 3.09Å; R35-V38 PolarHBondContact O-N 3.37Å; R35-Y39 PolarHBondContact O-N 3.17Å; R35-Y39 VanDerWaalsContact O-N 3.12Å; R35-E70 IonicContact CZ-OE2 2.65Å; R35-E70 IonicContact NE-OE1 3.42Å; R35-E70 IonicContact NE-OE2 3.61Å; R35-E70 PolarHBondContact NE-OE2 2.89Å; R35-E70 IonicContact NH2-OE1 2.8Å; R35-E70 PolarHBondContact NH2-OE1 3.43Å; R35-E70 IonicContact NH2-OE2 3.48Å; R35-E70 PolarHBondContact NH2-OE2 2.87Å; R35-E70 VanDerWaalsContact NH2-OE2 3.15Å; R35-Y74 VanDerWaalsContact CZ-OH 3.24Å; R35-Y74 PolarHBondContact NH1-OH 2.98Å; R35-Y74 PolarHBondContact NH2-OH 3.26Å
36A96.2Very high94.8Very high0 Ų027.7 Ų27.70%014%0.138CC..Hα-helixtrans-61.1-40.2174.600000111.4V14 I25 G32 K33 T34 Y39 V40V14-A36 HydrophobicContact CG1-CB 3.75Å; I25-A36 HydrophobicContact CD1-CB 4.4Å; G32-A36 PolarHBondContact O-N 3.04Å; G32-A36 VanDerWaalsContact O-N 3.12Å; K33-A36 WeakPolarHBondContact O-CB 3.33Å; K33-A36 PolarHBondContact O-N 3.39Å; T34-A36 PolarHBondContact O-N 3.36Å; A36-Y39 WeakPolarHBondContact O-CB 3.31Å; A36-Y39 PolarHBondContact O-N 2.88Å; A36-V40 WeakPolarHBondContact O-CG2 3.32Å; A36-V40 PolarHBondContact O-N 2.89Å
37A97.4Very high94.7Very high1 Ų130.1 Ų30.11%0.00816%0.16CC..Hα-helixtrans-65.3-40.3176.200000113.1K33 T34 R35 Y39 V40 A41 I133 L168 L170K33-A37 PolarHBondContact O-N 2.87Å; T34-A37 WeakPolarHBondContact O-CA 3.27Å; T34-A37 WeakPolarHBondContact O-CB 3.31Å; T34-A37 PolarHBondContact O-N 2.74Å; T34-A37 VanDerWaalsContact O-N 3.11Å; R35-A37 VanDerWaalsContact C-N 3.3Å; R35-A37 PolarHBondContact O-N 3.09Å; A37-Y39 VanDerWaalsContact C-N 3.27Å; A37-Y39 PolarHBondContact O-N 2.82Å; A37-V40 PolarHBondContact O-N 2.84Å; A37-A41 WeakPolarHBondContact O-CB 3.35Å; A37-A41 PolarHBondContact O-N 2.93Å; A37-I133 HydrophobicContact CB-CD1 4.32Å; A37-I133 HydrophobicContact CB-CG2 4.09Å; A37-L168 HydrophobicContact CB-CD2 4.01Å; A37-L170 HydrophobicContact CB-CD1 3.68Å; A37-L170 HydrophobicContact CB-CD2 4.06Å; A37-L170 HydrophobicContact CB-CG 4.44Å
38V97.7Very high94.7Very high0 Ų032.4 Ų32.40%017%0.174CC..Hα-helixtrans-60.2-39.6173175.70000110.7F4 T34 R35 A41 R42 E70 F71 Y74 L75F4-V38 HydrophobicContact CE2-CB 4.43Å; F4-V38 HydrophobicContact CE2-CG1 3.92Å; F4-V38 HydrophobicContact CZ-CB 4.02Å; F4-V38 HydrophobicContact CZ-CG1 3.65Å; T34-V38 WeakPolarHBondContact O-CG2 3.44Å; T34-V38 PolarHBondContact O-N 2.9Å; R35-V38 PolarHBondContact O-N 3.37Å; V38-A41 PolarHBondContact O-N 3.06Å; V38-R42 WeakPolarHBondContact O-CB 3.4Å; V38-R42 PolarHBondContact O-N 3.1Å; V38-E70 HydrophobicContact CG2-CB 3.95Å; V38-F71 HydrophobicContact CG2-CD1 4.09Å; V38-F71 HydrophobicContact CG2-CD2 3.73Å; V38-F71 HydrophobicContact CG2-CE1 4.05Å; V38-F71 HydrophobicContact CG2-CE2 3.69Å; V38-F71 HydrophobicContact CG2-CG 3.93Å; V38-F71 HydrophobicContact CG2-CZ 3.85Å; V38-Y74 HydrophobicContact CG1-CD2 4.31Å; V38-L75 HydrophobicContact CG1-CD1 4.29Å; V38-L75 HydrophobicContact CG1-CG 4.19Å
39Y97.6Very high94.8Very high39 Ų3934.8 Ų34.815%0.15320%0.196CC..Hα-helixtrans-64.7-44176.7-176.3-82.6000112.2F4 L6 V14 L18 R35 A36 A37 R42 R43F4-Y39 AromaticContact CD1-CD2 3.96Å; F4-Y39 HydrophobicContact CD1-CD2 3.96Å; F4-Y39 AromaticContact CE1-CD2 3.5Å; F4-Y39 HydrophobicContact CE1-CD2 3.5Å; F4-Y39 VanDerWaalsContact CE1-CD2 3.5Å; F4-Y39 AromaticContact CE1-CG 4Å; F4-Y39 HydrophobicContact CE1-CG 4Å; L6-Y39 HydrophobicContact CD1-CD1 3.71Å; L6-Y39 HydrophobicContact CD1-CD2 3.73Å; L6-Y39 HydrophobicContact CD1-CE1 4.32Å; L6-Y39 HydrophobicContact CD1-CE2 4.35Å; L6-Y39 HydrophobicContact CD1-CG 3.41Å; L6-Y39 VanDerWaalsContact CD1-CG 3.41Å; L6-Y39 HydrophobicContact CD2-CG 4.46Å; L6-Y39 HydrophobicContact CG-CD2 3.75Å; L6-Y39 HydrophobicContact CG-CE2 4.46Å; L6-Y39 HydrophobicContact CG-CG 3.88Å; V14-Y39 HydrophobicContact CG2-CD1 4.3Å; L18-Y39 HydrophobicContact CD1-CD1 4.42Å; L18-Y39 HydrophobicContact CD1-CE1 3.73Å; L18-Y39 HydrophobicContact CD2-CD1 4.13Å; L18-Y39 HydrophobicContact CD2-CE1 3.91Å; L18-Y39 HydrophobicContact CG-CE1 4.42Å; R35-Y39 PolarHBondContact O-N 3.17Å; R35-Y39 VanDerWaalsContact O-N 3.12Å; A36-Y39 WeakPolarHBondContact O-CB 3.31Å; A36-Y39 PolarHBondContact O-N 2.88Å; A37-Y39 VanDerWaalsContact C-N 3.27Å; A37-Y39 PolarHBondContact O-N 2.82Å; Y39-R42 PolarHBondContact O-N 3.46Å; Y39-R43 HydrophobicContact CD1-CG 4.1Å; Y39-R43 HydrophobicContact CE1-CG 3.66Å; Y39-R43 WeakPolarHBondContact O-CG 3.27Å; Y39-R43 PolarHBondContact O-N 2.8Å; Y39-R43 PolarHBondContact OH-NE 2.81Å; Y39-R43 VanDerWaalsContact OH-NE 3.14Å; Y39-R43 PolarHBondContact OH-NH2 3.36Å
40V98.2Very high95Very high2 Ų241.7 Ų41.71%0.01223%0.233CC..Hα-helixtrans-61.5-46.7174.7176.30000110.5V14 A17 L18 A36 A37 R42 R43 H44 L131 L168V14-V40 HydrophobicContact CB-CG2 3.76Å; V14-V40 HydrophobicContact CG1-CG2 3.72Å; A17-V40 HydrophobicContact CB-CG1 4.04Å; A17-V40 HydrophobicContact CB-CG2 4.01Å; L18-V40 HydrophobicContact CD2-CG2 4.36Å; A36-V40 WeakPolarHBondContact O-CG2 3.32Å; A36-V40 PolarHBondContact O-N 2.89Å; A37-V40 PolarHBondContact O-N 2.84Å; V40-R42 VanDerWaalsContact C-N 3.35Å; V40-R42 PolarHBondContact O-N 3.49Å; V40-R43 PolarHBondContact O-N 3.46Å; V40-H44 VanDerWaalsContact O-CB 3.29Å; V40-H44 WeakPolarHBondContact O-CB 3.15Å; V40-H44 PolarHBondContact O-N 2.98Å; V40-L131 HydrophobicContact CG1-CD2 4.25Å; V40-L168 HydrophobicContact CB-CD2 3.97Å; V40-L168 HydrophobicContact CG1-CD2 4.01Å; V40-L168 HydrophobicContact CG2-CD2 4.22Å
41A98.2Very high95.6Very high0 Ų040.7 Ų40.70%022%0.222CC..Hα-helixtrans-57.7-46177.400000112A37 V38 R43 H44 L45 V53 F71 L75 L131 I133A37-A41 WeakPolarHBondContact O-CB 3.35Å; A37-A41 PolarHBondContact O-N 2.93Å; V38-A41 PolarHBondContact O-N 3.06Å; A41-R43 PolarHBondContact O-N 2.89Å; A41-H44 PolarHBondContact O-N 3.19Å; A41-L45 WeakPolarHBondContact O-CB 3.44Å; A41-L45 WeakPolarHBondContact O-CD1 3.06Å; A41-L45 VanDerWaalsContact O-CG 3.26Å; A41-L45 WeakPolarHBondContact O-CG 3.41Å; A41-L45 PolarHBondContact O-N 2.88Å; A41-V53 HydrophobicContact CB-CG1 4.07Å; A41-V53 HydrophobicContact CB-CG2 4.45Å; A41-F71 HydrophobicContact CB-CE1 4.21Å; A41-L75 HydrophobicContact CB-CD1 4.38Å; A41-L131 HydrophobicContact CB-CD2 4.47Å; A41-I133 HydrophobicContact CB-CD1 4.08Å
42R97Very high96Very high52 Ų5242.2 Ų42.220%0.19623%0.228CC..Hα-helixtrans-57.3-52177-166.9178.460.7171.4-0.3111.6V38 Y39 V40 H44 L45 E46 L75V38-R42 WeakPolarHBondContact O-CB 3.4Å; V38-R42 PolarHBondContact O-N 3.1Å; Y39-R42 PolarHBondContact O-N 3.46Å; V40-R42 VanDerWaalsContact C-N 3.35Å; V40-R42 PolarHBondContact O-N 3.49Å; R42-H44 VanDerWaalsContact C-N 3.3Å; R42-H44 PolarHBondContact O-N 3.34Å; R42-L45 PolarHBondContact O-N 2.81Å; R42-E46 WeakPolarHBondContact CG-OE1 3.37Å; R42-E46 IonicContact NE-OE1 3.76Å; R42-E46 VanDerWaalsContact O-CG 3.32Å; R42-E46 WeakPolarHBondContact O-CG 3.33Å; R42-E46 PolarHBondContact O-N 3.14Å; R42-L75 HydrophobicContact CB-CD2 3.62Å; R42-L75 HydrophobicContact CG-CD2 3.65Å
43R97.1Very high96.3Very high100 Ų10041 Ų4138%0.37722%0.216SC..Hα-helixtrans-63.6-39.1-179.1-69.5-54.1-164.4168.15.4111.6L18 Y39 V40 A41 E46 T47L18-R43 HydrophobicContact CD2-CB 3.61Å; L18-R43 HydrophobicContact CD2-CG 3.71Å; Y39-R43 HydrophobicContact CD1-CG 4.1Å; Y39-R43 HydrophobicContact CE1-CG 3.66Å; Y39-R43 WeakPolarHBondContact O-CG 3.27Å; Y39-R43 PolarHBondContact O-N 2.8Å; Y39-R43 PolarHBondContact OH-NE 2.81Å; Y39-R43 VanDerWaalsContact OH-NE 3.14Å; Y39-R43 PolarHBondContact OH-NH2 3.36Å; V40-R43 PolarHBondContact O-N 3.46Å; A41-R43 PolarHBondContact O-N 2.89Å; R43-E46 WeakPolarHBondContact CD-OE2 3.47Å; R43-E46 IonicContact CZ-OE2 3.02Å; R43-E46 IonicContact NE-OE2 3.36Å; R43-E46 IonicContact NH1-OE2 3.1Å; R43-E46 PolarHBondContact NH1-OE2 2.86Å; R43-E46 PolarHBondContact O-N 3.2Å; R43-T47 WeakPolarHBondContact O-CG2 3.23Å; R43-T47 PolarHBondContact O-N 2.63Å; R43-T47 PolarHBondContact O-OG1 3.44Å
44H98Very high96.5Very high18 Ų1840.2 Ų40.28%0.08321%0.213CC..Hα-helixtrans-61.7-45.3176-173.183.8000112.1V40 A41 R42 E46 T47 T48 T130 L131V40-H44 VanDerWaalsContact O-CB 3.29Å; V40-H44 WeakPolarHBondContact O-CB 3.15Å; V40-H44 PolarHBondContact O-N 2.98Å; A41-H44 PolarHBondContact O-N 3.19Å; R42-H44 VanDerWaalsContact C-N 3.3Å; R42-H44 PolarHBondContact O-N 3.34Å; H44-E46 VanDerWaalsContact C-N 3.35Å; H44-T47 PolarHBondContact O-N 3.44Å; H44-T48 WeakPolarHBondContact O-CB 3.35Å; H44-T48 PolarHBondContact O-N 3.35Å; H44-T48 PolarHBondContact O-OG1 3.33Å; H44-T130 WeakPolarHBondContact NE2-CB 3.37Å; H44-T130 PolarHBondContact NE2-OG1 2.95Å; H44-L131 HydrophobicContact CB-CD2 3.92Å
45L97.7Very high96.8Very high15 Ų1539.1 Ų39.18%0.07921%0.206CC..Hα-helixtrans-63.5-38.2175.6-70.2159.1000112.4A41 R42 A51 V53 L75 Y79 D102 V103A41-L45 WeakPolarHBondContact O-CB 3.44Å; A41-L45 WeakPolarHBondContact O-CD1 3.06Å; A41-L45 VanDerWaalsContact O-CG 3.26Å; A41-L45 WeakPolarHBondContact O-CG 3.41Å; A41-L45 PolarHBondContact O-N 2.88Å; R42-L45 PolarHBondContact O-N 2.81Å; L45-A51 HydrophobicContact CD2-CB 3.82Å; L45-A51 HydrophobicContact CG-CB 4.47Å; L45-V53 HydrophobicContact CD1-CG2 4.27Å; L45-V53 HydrophobicContact CD2-CG2 3.96Å; L45-V53 HydrophobicContact CG-CG2 3.88Å; L45-L75 HydrophobicContact CD1-CD1 4.33Å; L45-Y79 HydrophobicContact CB-CD1 4.29Å; L45-Y79 HydrophobicContact CB-CE1 3.62Å; L45-Y79 HydrophobicContact CB-CE2 4.13Å; L45-Y79 HydrophobicContact CD1-CD1 4.15Å; L45-Y79 HydrophobicContact CD1-CD2 3.96Å; L45-Y79 HydrophobicContact CD1-CE1 4.26Å; L45-Y79 HydrophobicContact CD1-CE2 4.06Å; L45-Y79 HydrophobicContact CD1-CG 3.99Å; L45-Y79 HydrophobicContact CD2-CD1 4.11Å; L45-Y79 HydrophobicContact CD2-CE1 4.19Å; L45-Y79 HydrophobicContact CG-CD1 4.43Å; L45-Y79 HydrophobicContact CG-CE1 4.24Å; L45-D102 HydrophobicContact CD2-CB 4.09Å; L45-V103 HydrophobicContact CD1-CG2 3.69Å; L45-V103 HydrophobicContact CD2-CG2 4.39Å
46E95.9Very high97Very high92 Ų9236.7 Ų36.743%0.4320%0.197SC..Hα-helixtrans-67.5-34177.4-73.8168.1-173.100112.9R42 R43 H44R42-E46 WeakPolarHBondContact CG-OE1 3.37Å; R42-E46 IonicContact NE-OE1 3.76Å; R42-E46 VanDerWaalsContact O-CG 3.32Å; R42-E46 WeakPolarHBondContact O-CG 3.33Å; R42-E46 PolarHBondContact O-N 3.14Å; R43-E46 WeakPolarHBondContact CD-OE2 3.47Å; R43-E46 IonicContact CZ-OE2 3.02Å; R43-E46 IonicContact NE-OE2 3.36Å; R43-E46 IonicContact NH1-OE2 3.1Å; R43-E46 PolarHBondContact NH1-OE2 2.86Å; R43-E46 PolarHBondContact O-N 3.2Å; H44-E46 VanDerWaalsContact C-N 3.35Å
47T96.2Very high96.9Very high111 Ų11136.7 Ų36.768%0.68120%0.197SC*.Hα-helixtrans-107.1-13.5-169.462.30000114.6R43 H44R43-T47 WeakPolarHBondContact O-CG2 3.23Å; R43-T47 PolarHBondContact O-N 2.63Å; R43-T47 PolarHBondContact O-OG1 3.44Å; H44-T47 PolarHBondContact O-N 3.44Å
48T95.6Very high96.5Very high49 Ų4939 Ų3930%0.30121%0.209SC..SBendtrans-111.2122.5-175.7-570000110.8H44 A51H44-T48 WeakPolarHBondContact O-CB 3.35Å; H44-T48 PolarHBondContact O-N 3.35Å; H44-T48 PolarHBondContact O-OG1 3.33Å; T48-A51 HydrophobicContact CG2-CB 4.35Å; T48-A51 VanDerWaalsContact O-CB 3.3Å; T48-A51 WeakPolarHBondContact O-CB 3.38Å; T48-A51 PolarHBondContact O-N 3.21Å
49A92.3Very high95.9Very high88 Ų8841 Ų4173%0.72722%0.218SC*.THydrogen-bonded Turntrans-64.8136.5175.400000111.4A51A49-A51 PolarHBondContact O-N 2.9Å
50N92.3Very high95.1Very high160 Ų16040.8 Ų40.886%0.85622%0.221SC*.THydrogen-bonded Turntrans52.736.5-176.3-55.4-38.1000112.8K52N50-K52 PolarHBondContact O-N 3.05Å
51A96.9Very high94.2Very high9 Ų942.2 Ų42.27%0.07423%0.227CC..  trans-57.8135.1179.900000111.5L45 T48 A49L45-A51 HydrophobicContact CD2-CB 3.82Å; L45-A51 HydrophobicContact CG-CB 4.47Å; T48-A51 HydrophobicContact CG2-CB 4.35Å; T48-A51 VanDerWaalsContact O-CB 3.3Å; T48-A51 WeakPolarHBondContact O-CB 3.38Å; T48-A51 PolarHBondContact O-N 3.21Å; A49-A51 PolarHBondContact O-N 2.9Å
52K98.1Very high93.8Very high31 Ų3142.2 Ų42.214%0.13523%0.227CC..  trans-131.6118.2174.3-164.5134.6-59.7-167.50109.5N50 V98 Q99 N101 I104 D128 T130 L131N50-K52 PolarHBondContact O-N 3.05Å; K52-V98 HydrophobicContact CD-CG1 3.71Å; K52-V98 VanDerWaalsContact CD-O 3.27Å; K52-V98 WeakPolarHBondContact CD-O 3.35Å; K52-V98 VanDerWaalsContact CE-O 3.31Å; K52-V98 WeakPolarHBondContact CE-O 3.38Å; K52-V98 PolarHBondContact NZ-O 3.07Å; K52-Q99 PolarHBondContact NZ-O 2.93Å; K52-N101 WeakPolarHBondContact CE-O 3.17Å; K52-N101 PolarHBondContact NZ-O 3.14Å; K52-I104 HydrophobicContact CG-CD1 4.43Å; K52-D128 VanDerWaalsContact CB-O 3.23Å; K52-D128 WeakPolarHBondContact CB-O 3.33Å; K52-D128 WeakPolarHBondContact CD-O 3.41Å; K52-D128 WeakPolarHBondContact CG-O 3.37Å; K52-T130 PolarHBondContact N-OG1 3.12Å; K52-T130 PolarHBondContact O-N 3.02Å; K52-T130 PolarHBondContact O-OG1 2.98Å; K52-L131 PolarHBondContact O-N 3.03Å; K52-L131 VanDerWaalsContact O-N 3.09Å
53V98.6Very high93.4Very high0 Ų039.8 Ų39.80%022%0.218CC..EExtended strand (participates in β ladder)trans-108.8125-178.1-176.40000109.4A41 L45 V55 D102 V103 I104 L131 I133A41-V53 HydrophobicContact CB-CG1 4.07Å; A41-V53 HydrophobicContact CB-CG2 4.45Å; L45-V53 HydrophobicContact CD1-CG2 4.27Å; L45-V53 HydrophobicContact CD2-CG2 3.96Å; L45-V53 HydrophobicContact CG-CG2 3.88Å; V53-V55 HydrophobicContact CG1-CG2 4.33Å; V53-D102 PolarHBondContact N-O 2.89Å; V53-V103 HydrophobicContact CB-CG1 4.41Å; V53-V103 HydrophobicContact CB-CG2 4.19Å; V53-V103 CarbonylContact O-C 3.38Å; V53-V103 WeakPolarHBondContact O-CA 3.42Å; V53-I104 PolarHBondContact O-N 2.99Å; V53-L131 WeakPolarHBondContact CA-O 3.33Å; V53-L131 HydrophobicContact CG1-CB 4.5Å; V53-L131 HydrophobicContact CG1-CD2 4.09Å; V53-L131 HydrophobicContact CG1-CG 4.33Å; V53-L131 HydrophobicContact CG2-CB 4.28Å; V53-L131 HydrophobicContact CG2-CD2 4.22Å; V53-I133 HydrophobicContact CG1-CD1 3.92Å; V53-I133 HydrophobicContact CG1-CG1 4.29Å
54M98.6Very high93Very high0 Ų038.2 Ų38.20%022%0.217CC..EExtended strand (participates in β ladder)trans-115.1127.1175.6-176.870.86500109.4L56 F94 V98 I104 C106 L111 I129 L131 L132 I133M54-L56 HydrophobicContact CG-CD2 3.8Å; M54-L56 HydrophobicContact SD-CD2 4.4Å; M54-F94 HydrophobicContact CE-CE1 4.18Å; M54-F94 HydrophobicContact CE-CZ 3.88Å; M54-F94 HydrophobicContact SD-CZ 4.15Å; M54-V98 HydrophobicContact CE-CG2 3.68Å; M54-I104 CarbonylContact C-O 3.49Å; M54-I104 WeakPolarHBondContact CA-O 3.49Å; M54-I104 HydrophobicContact CE-CB 4Å; M54-I104 HydrophobicContact CE-CD1 4.44Å; M54-I104 HydrophobicContact CE-CG2 4.22Å; M54-I104 HydrophobicContact SD-CB 3.78Å; M54-I104 HydrophobicContact SD-CG2 3.82Å; M54-C106 VanDerWaalsContact SD-SG 3.64Å; M54-L111 HydrophobicContact CE-CD1 4.47Å; M54-L111 HydrophobicContact CG-CD2 4.21Å; M54-I129 HydrophobicContact CB-CD1 4.02Å; M54-I129 HydrophobicContact CB-CG1 4.37Å; M54-I129 HydrophobicContact CB-CG2 3.77Å; M54-I129 HydrophobicContact CE-CD1 4.14Å; M54-I129 HydrophobicContact CG-CD1 4.18Å; M54-L131 PolarHBondContact N-O 2.98Å; M54-L132 HydrophobicContact CB-CD1 3.77Å; M54-L132 HydrophobicContact CG-CD1 3.74Å; M54-L132 WeakPolarHBondContact O-CA 3.45Å; M54-I133 PolarHBondContact O-N 3.35Å
55V98.7Very high92.5Very high3 Ų338.3 Ų38.32%0.01822%0.218CC..EExtended strand (participates in β ladder)trans-112.8114.4179-1710000109V53 F71 I104 I105 C106 I133V53-V55 HydrophobicContact CG1-CG2 4.33Å; V55-F71 HydrophobicContact CB-CZ 4.49Å; V55-F71 HydrophobicContact CG1-CE2 4.31Å; V55-F71 HydrophobicContact CG1-CZ 4.18Å; V55-F71 HydrophobicContact CG2-CD1 4.44Å; V55-F71 HydrophobicContact CG2-CE1 3.65Å; V55-F71 HydrophobicContact CG2-CE2 4.27Å; V55-F71 HydrophobicContact CG2-CZ 3.55Å; V55-I104 PolarHBondContact N-O 3.19Å; V55-I105 HydrophobicContact CB-CB 4.37Å; V55-I105 HydrophobicContact CB-CG1 4.06Å; V55-I105 HydrophobicContact CB-CG2 4.26Å; V55-I105 HydrophobicContact CG1-CG2 4.39Å; V55-I105 HydrophobicContact CG2-CG1 4.16Å; V55-I105 WeakPolarHBondContact O-CA 3.44Å; V55-C106 PolarHBondContact O-N 2.87Å; V55-I133 CarbonylContact C-O 3.56Å; V55-I133 WeakPolarHBondContact CA-O 2.99Å; V55-I133 HydrophobicContact CG1-CB 4.31Å; V55-I133 HydrophobicContact CG1-CG2 4.31Å; V55-I133 HydrophobicContact CG2-CB 4.29Å; V55-I133 HydrophobicContact CG2-CD1 4.25Å
56L98.3Very high92.3Very high0 Ų038 Ų380%022%0.216CC..EExtended strand (participates in β ladder)trans-97.6131.8179-54.3-172.5000111.2M54 C106 L111 L132 I133 I134 D135 Y146 I149M54-L56 HydrophobicContact CG-CD2 3.8Å; M54-L56 HydrophobicContact SD-CD2 4.4Å; L56-C106 WeakPolarHBondContact CA-O 3.47Å; L56-L111 HydrophobicContact CD1-CD2 4.06Å; L56-L111 HydrophobicContact CD2-CB 4.06Å; L56-L111 HydrophobicContact CD2-CD2 3.85Å; L56-L111 HydrophobicContact CG-CD2 4.45Å; L56-L132 HydrophobicContact CD1-CD1 3.87Å; L56-L132 HydrophobicContact CD1-CD2 4.44Å; L56-L132 HydrophobicContact CD1-CG 4.43Å; L56-L132 HydrophobicContact CD2-CD1 4.3Å; L56-L132 HydrophobicContact CG-CD1 3.76Å; L56-I133 PolarHBondContact N-O 2.9Å; L56-I134 HydrophobicContact CD1-CG1 4.34Å; L56-D135 WeakPolarHBondContact O-CB 3.4Å; L56-D135 PolarHBondContact O-N 2.93Å; L56-Y146 HydrophobicContact CB-CD1 4.48Å; L56-Y146 HydrophobicContact CB-CE1 3.8Å; L56-Y146 HydrophobicContact CD1-CD1 4.38Å; L56-Y146 HydrophobicContact CD1-CE1 4.48Å; L56-Y146 PolarHBondContact O-OH 3.23Å; L56-I149 HydrophobicContact CD1-CD1 3.74Å
57V94.9Very high92.2Very high0 Ų035.5 Ų35.50%020%0.202CC..EExtended strand (participates in β ladder)trans-122.5157.2172.2-59.40000111.6K59 L62 V63 H66 C106 T107 A108 D135 Y146V57-K59 VanDerWaalsContact CG2-O 3.32Å; V57-K59 WeakPolarHBondContact CG2-O 3.2Å; V57-L62 HydrophobicContact CB-CB 3.77Å; V57-L62 HydrophobicContact CB-CD1 4.24Å; V57-L62 HydrophobicContact CG1-CB 3.89Å; V57-L62 HydrophobicContact CG2-CB 3.98Å; V57-V63 HydrophobicContact CG2-CB 4.49Å; V57-V63 HydrophobicContact CG2-CG2 3.42Å; V57-V63 VanDerWaalsContact CG2-CG2 3.42Å; V57-H66 VanDerWaalsContact CG1-CD2 3.47Å; V57-H66 WeakPolarHBondContact CG1-CD2 3.27Å; V57-C106 PolarHBondContact N-O 2.81Å; V57-T107 HydrophobicContact CG2-CG2 4.27Å; V57-T107 WeakPolarHBondContact O-CA 3.5Å; V57-A108 PolarHBondContact O-N 3.46Å; V57-A108 VanDerWaalsContact O-N 3.1Å; V57-D135 HydrophobicContact CG1-CB 4.21Å; V57-Y146 VanDerWaalsContact CA-OH 3.23Å; V57-Y146 WeakPolarHBondContact CA-OH 3.49Å
58N88.9Confident92Very high51 Ų5133.8 Ų33.827%0.27319%0.192SC..SBendtrans-91.7-12.3-178.368-16.8000113.5L62 H139 Y146 E445N58-L62 VanDerWaalsContact OD1-CD1 3.31Å; N58-L62 WeakPolarHBondContact OD1-CD1 3.47Å; N58-H139 PolarHBondContact ND2-CD2 3.1Å; N58-H139 VanDerWaalsContact ND2-CD2 3.35Å; N58-H139 PolarHBondContact ND2-NE2 2.92Å; N58-Y146 HydrophobicContact CB-CE2 4.4Å; N58-Y146 PolarHBondContact N-OH 3.42Å; N58-E445 PolarHBondContact ND2-OE2 2.97Å
59K84.6Confident91.6Very high41 Ų4135.1 Ų35.118%0.17819%0.194CC..SBendtrans-135147.1-177.9-61.8-178.6-170.1175.20111.1V57 H61 L62 V442 E445V57-K59 VanDerWaalsContact CG2-O 3.32Å; V57-K59 WeakPolarHBondContact CG2-O 3.2Å; K59-H61 WeakPolarHBondContact CD-CE1 3.26Å; K59-L62 HydrophobicContact CB-CD1 4.14Å; K59-L62 HydrophobicContact CB-CG 4.27Å; K59-L62 WeakPolarHBondContact O-CB 3.4Å; K59-L62 PolarHBondContact O-N 2.8Å; K59-V442 PolarHBondContact NZ-O 2.94Å; K59-E445 PolarHBondContact NZ-O 3.44Å
60V81.6Confident91.6Very high35 Ų3532.8 Ų32.821%0.21217%0.168CC..Hα-helixtrans-65.1-44.3-176.8178.60000112.5L62 V63 S85 T107 Q419V60-L62 PolarHBondContact O-N 2.69Å; V60-V63 VanDerWaalsContact O-CB 3.24Å; V60-V63 WeakPolarHBondContact O-CB 3.2Å; V60-V63 WeakPolarHBondContact O-CG2 3.47Å; V60-V63 PolarHBondContact O-N 3.22Å; V60-S85 VanDerWaalsContact CG1-CB 3.5Å; V60-T107 HydrophobicContact CB-CG2 4.43Å; V60-T107 HydrophobicContact CG2-CG2 3.83Å; V60-Q419 VanDerWaalsContact CB-OE1 3.28Å
61H79.9Confident91.8Very high31 Ų3125.3 Ų25.314%0.14413%0.128CC..Hα-helixtrans-60.2-20.6-179.866.4-104.2000113.8K59 V63 Q65K59-H61 WeakPolarHBondContact CD-CE1 3.26Å; H61-V63 VanDerWaalsContact C-N 3.32Å; H61-Q65 VanDerWaalsContact O-CB 3.32Å; H61-Q65 WeakPolarHBondContact O-CB 3.19Å; H61-Q65 PolarHBondContact O-N 3.49Å; H61-Q65 VanDerWaalsContact O-N 3.16Å
62L88Confident91.7Very high0 Ų028.8 Ų28.80%014%0.143CC..Hα-helixtrans-72.3-26.9175-72.9176.1000112.6V57 N58 K59 V60 Q65 H66 G446V57-L62 HydrophobicContact CB-CB 3.77Å; V57-L62 HydrophobicContact CB-CD1 4.24Å; V57-L62 HydrophobicContact CG1-CB 3.89Å; V57-L62 HydrophobicContact CG2-CB 3.98Å; N58-L62 VanDerWaalsContact OD1-CD1 3.31Å; N58-L62 WeakPolarHBondContact OD1-CD1 3.47Å; K59-L62 HydrophobicContact CB-CD1 4.14Å; K59-L62 HydrophobicContact CB-CG 4.27Å; K59-L62 WeakPolarHBondContact O-CB 3.4Å; K59-L62 PolarHBondContact O-N 2.8Å; V60-L62 PolarHBondContact O-N 2.69Å; L62-Q65 PolarHBondContact O-N 3.07Å; L62-H66 WeakPolarHBondContact O-CB 3.31Å; L62-H66 VanDerWaalsContact O-CG 3.29Å; L62-H66 PolarHBondContact O-N 2.92Å; L62-G446 VanDerWaalsContact CD2-O 3.22Å; L62-G446 WeakPolarHBondContact CD2-O 3.48Å
63V90.4Very high91.6Very high2 Ų230.5 Ų30.51%0.01216%0.157CC..Hα-helixtrans-59.8-55.9175.8176.50000109.3V57 V60 H61 Q65 Y67 K83 I105 T107V57-V63 HydrophobicContact CG2-CB 4.49Å; V57-V63 HydrophobicContact CG2-CG2 3.42Å; V57-V63 VanDerWaalsContact CG2-CG2 3.42Å; V60-V63 VanDerWaalsContact O-CB 3.24Å; V60-V63 WeakPolarHBondContact O-CB 3.2Å; V60-V63 WeakPolarHBondContact O-CG2 3.47Å; V60-V63 PolarHBondContact O-N 3.22Å; H61-V63 VanDerWaalsContact C-N 3.32Å; V63-Q65 VanDerWaalsContact C-N 3.35Å; V63-Q65 PolarHBondContact O-N 3.29Å; V63-Y67 VanDerWaalsContact O-CB 3.26Å; V63-Y67 WeakPolarHBondContact O-CB 3.49Å; V63-Y67 PolarHBondContact O-N 2.88Å; V63-K83 HydrophobicContact CG1-CB 3.66Å; V63-I105 HydrophobicContact CG1-CG2 4.22Å; V63-T107 HydrophobicContact CG2-CG2 3.95Å
64D87.5Confident91.3Very high67 Ų6734 Ų3436%0.35817%0.17SC..Hα-helixtrans-65.2-39179.1-70.9-51.4000112.4T68 K83D64-T68 WeakPolarHBondContact O-CB 3.41Å; D64-T68 PolarHBondContact O-N 3.14Å; D64-T68 PolarHBondContact O-OG1 3.3Å; D64-K83 WeakPolarHBondContact OD1-CD 3.32Å; D64-K83 WeakPolarHBondContact OD1-CE 3.44Å; D64-K83 IonicContact OD1-NZ 3.82Å; D64-K83 PolarHBondContact OD1-NZ 3.31Å
65Q87.7Confident91.2Very high20 Ų2034.1 Ų34.19%0.09317%0.171CC..Hα-helixtrans-62.7-50.2180-175177.9-69.100111.6H61 L62 V63 K69 G446H61-Q65 VanDerWaalsContact O-CB 3.32Å; H61-Q65 WeakPolarHBondContact O-CB 3.19Å; H61-Q65 PolarHBondContact O-N 3.49Å; H61-Q65 VanDerWaalsContact O-N 3.16Å; L62-Q65 PolarHBondContact O-N 3.07Å; V63-Q65 VanDerWaalsContact C-N 3.35Å; V63-Q65 PolarHBondContact O-N 3.29Å; Q65-K69 HydrophobicContact CG-CD 4.12Å; Q65-K69 VanDerWaalsContact O-CB 3.28Å; Q65-K69 WeakPolarHBondContact O-CB 3.49Å; Q65-K69 PolarHBondContact O-N 3.27Å; Q65-G446 PolarHBondContact NE2-O 3.11Å; Q65-G446 PolarHBondContact OE1-O 2.67Å
66H93.1Very high90.9Very high8 Ų835.8 Ų35.84%0.03719%0.189CC..Hα-helixtrans-70.2-37.8-179.2-67-19.8000111.3T34 V57 L62 E70 F71 I105 D135T34-H66 HydrophobicContact CG2-CB 4.47Å; V57-H66 VanDerWaalsContact CG1-CD2 3.47Å; V57-H66 WeakPolarHBondContact CG1-CD2 3.27Å; L62-H66 WeakPolarHBondContact O-CB 3.31Å; L62-H66 VanDerWaalsContact O-CG 3.29Å; L62-H66 PolarHBondContact O-N 2.92Å; H66-E70 WeakPolarHBondContact O-CB 3.41Å; H66-E70 PolarHBondContact O-N 3.44Å; H66-F71 HydrophobicContact CB-CD2 4.25Å; H66-F71 HydrophobicContact CB-CE2 4.46Å; H66-F71 PolarHBondContact O-N 3.3Å; H66-I105 HydrophobicContact CB-CD1 4.43Å; H66-D135 IonicContact CD2-OD2 3.91Å; H66-D135 IonicContact CE1-OD2 3.44Å; H66-D135 IonicContact NE2-OD2 2.63Å; H66-D135 PolarHBondContact NE2-OD2 3.41Å
67Y94.3Very high90.6Very high39 Ų3941 Ų4115%0.15323%0.225CC..Iπ-helixtrans-58.4-60.6174.5-171.4-85.2000111.1V63 F71 E72 L81 K83 I105V63-Y67 VanDerWaalsContact O-CB 3.26Å; V63-Y67 WeakPolarHBondContact O-CB 3.49Å; V63-Y67 PolarHBondContact O-N 2.88Å; Y67-F71 PolarHBondContact O-N 3.41Å; Y67-E72 HydrophobicContact CD1-CB 3.98Å; Y67-E72 HydrophobicContact CE1-CB 3.82Å; Y67-E72 HydrophobicContact CE1-CG 4.02Å; Y67-E72 WeakPolarHBondContact O-CB 3.5Å; Y67-E72 PolarHBondContact O-N 3.32Å; Y67-L81 HydrophobicContact CE2-CB 3.75Å; Y67-L81 PolarHBondContact OH-O 2.94Å; Y67-K83 HydrophobicContact CD1-CD 4.22Å; Y67-K83 HydrophobicContact CD2-CB 3.73Å; Y67-K83 HydrophobicContact CD2-CD 4.34Å; Y67-K83 HydrophobicContact CD2-CG 4.21Å; Y67-K83 HydrophobicContact CE2-CB 4.22Å; Y67-K83 HydrophobicContact CE2-CG 4.37Å; Y67-K83 HydrophobicContact CG-CB 4.16Å; Y67-K83 HydrophobicContact CG-CD 4.07Å; Y67-K83 HydrophobicContact CG-CG 4.44Å; Y67-I105 HydrophobicContact CD2-CD1 4.14Å
68T91.1Very high90.5Very high76 Ų7643.6 Ų43.647%0.46625%0.252SS..Iπ-helixtrans-74-35.3-168.4-43.50000113D64 P73D64-T68 WeakPolarHBondContact O-CB 3.41Å; D64-T68 PolarHBondContact O-N 3.14Å; D64-T68 PolarHBondContact O-OG1 3.3Å; T68-P73 WeakPolarHBondContact O-CD 3.37Å; T68-P73 WeakPolarHBondContact O-CG 3.36Å
69K88.1Confident90.9Very high77 Ų7744.1 Ų44.134%0.33525%0.251SS..Iπ-helixtrans-91.8-27.6-175.1-67.7-173.1166-174.60114.1Q65 D448Q65-K69 HydrophobicContact CG-CD 4.12Å; Q65-K69 VanDerWaalsContact O-CB 3.28Å; Q65-K69 WeakPolarHBondContact O-CB 3.49Å; Q65-K69 PolarHBondContact O-N 3.27Å; K69-D448 IonicContact NZ-OD2 3.02Å; K69-D448 PolarHBondContact NZ-OD2 3Å
70E92.4Very high91.5Very high39 Ų3948.4 Ų48.418%0.18227%0.269CS..Iπ-helixtrans-124.8-61.1-167.1-64.4-69.3161.200111.5T34 R35 V38 H66 Y74T34-E70 HydrophobicContact CG2-CB 3.9Å; T34-E70 HydrophobicContact CG2-CG 3.75Å; R35-E70 IonicContact CZ-OE2 2.65Å; R35-E70 IonicContact NE-OE1 3.42Å; R35-E70 IonicContact NE-OE2 3.61Å; R35-E70 PolarHBondContact NE-OE2 2.89Å; R35-E70 IonicContact NH2-OE1 2.8Å; R35-E70 PolarHBondContact NH2-OE1 3.43Å; R35-E70 IonicContact NH2-OE2 3.48Å; R35-E70 PolarHBondContact NH2-OE2 2.87Å; R35-E70 VanDerWaalsContact NH2-OE2 3.15Å; V38-E70 HydrophobicContact CG2-CB 3.95Å; H66-E70 WeakPolarHBondContact O-CB 3.41Å; H66-E70 PolarHBondContact O-N 3.44Å; E70-Y74 WeakPolarHBondContact O-CD2 3.4Å
71F95.8Very high92.2Very high2 Ų247.6 Ų47.61%0.00926%0.264CS..Iπ-helixtrans-75.5-50.4-171.2-78.3-99.2000113.7T34 V38 A41 V55 H66 Y67 Y74 L75 L81 V103 I105 I133T34-F71 HydrophobicContact CG2-CE2 4.14Å; V38-F71 HydrophobicContact CG2-CD1 4.09Å; V38-F71 HydrophobicContact CG2-CD2 3.73Å; V38-F71 HydrophobicContact CG2-CE1 4.05Å; V38-F71 HydrophobicContact CG2-CE2 3.69Å; V38-F71 HydrophobicContact CG2-CG 3.93Å; V38-F71 HydrophobicContact CG2-CZ 3.85Å; A41-F71 HydrophobicContact CB-CE1 4.21Å; V55-F71 HydrophobicContact CB-CZ 4.49Å; V55-F71 HydrophobicContact CG1-CE2 4.31Å; V55-F71 HydrophobicContact CG1-CZ 4.18Å; V55-F71 HydrophobicContact CG2-CD1 4.44Å; V55-F71 HydrophobicContact CG2-CE1 3.65Å; V55-F71 HydrophobicContact CG2-CE2 4.27Å; V55-F71 HydrophobicContact CG2-CZ 3.55Å; H66-F71 HydrophobicContact CB-CD2 4.25Å; H66-F71 HydrophobicContact CB-CE2 4.46Å; H66-F71 PolarHBondContact O-N 3.3Å; Y67-F71 PolarHBondContact O-N 3.41Å; F71-Y74 PolarHBondContact O-N 3.31Å; F71-L75 HydrophobicContact CD1-CD1 3.89Å; F71-L75 WeakPolarHBondContact O-CB 3.49Å; F71-L75 PolarHBondContact O-N 3.16Å; F71-L81 VanDerWaalsContact C-CD2 3.49Å; F71-L81 HydrophobicContact CB-CD2 3.93Å; F71-L81 WeakPolarHBondContact O-CD2 3.33Å; F71-V103 HydrophobicContact CD1-CG1 3.92Å; F71-V103 HydrophobicContact CE1-CG1 4.32Å; F71-I105 HydrophobicContact CB-CD1 3.7Å; F71-I105 HydrophobicContact CD1-CD1 4.37Å; F71-I105 HydrophobicContact CD2-CD1 3.69Å; F71-I105 HydrophobicContact CE2-CD1 4.43Å; F71-I105 HydrophobicContact CG-CD1 3.66Å; F71-I133 HydrophobicContact CZ-CD1 4.39Å
72E95.8Very high93Very high83 Ų8348 Ų4839%0.38827%0.266SS..Hα-helixtrans-59.7-48.1-178.3178.3-161.2-136.600112.6Y67 Y74 G76 L81Y67-E72 HydrophobicContact CD1-CB 3.98Å; Y67-E72 HydrophobicContact CE1-CB 3.82Å; Y67-E72 HydrophobicContact CE1-CG 4.02Å; Y67-E72 WeakPolarHBondContact O-CB 3.5Å; Y67-E72 PolarHBondContact O-N 3.32Å; E72-Y74 PolarHBondContact O-N 2.84Å; E72-Y74 VanDerWaalsContact O-N 3.12Å; E72-G76 WeakPolarHBondContact O-CA 3.32Å; E72-G76 PolarHBondContact O-N 3.42Å; E72-L81 HydrophobicContact CB-CD2 4.32Å
73P94.6Very high93.3Very high67 Ų6751.5 Ų51.544%0.43528%0.281SS..Hα-helixtrans-62-24.7-177.7-26.136.6000115.1T68T68-P73 WeakPolarHBondContact O-CD 3.37Å; T68-P73 WeakPolarHBondContact O-CG 3.36Å
74Y93.9Very high93.4Very high73 Ų7351.4 Ų51.429%0.28628%0.281SS..Hα-helixtrans-110.6-18.8-174.8-57.7-58.8000114.5F4 R35 V38 E70 F71 E72F4-Y74 HydrophobicContact CB-CD1 4.26Å; F4-Y74 AromaticContact CD2-CD1 3.28Å; F4-Y74 HydrophobicContact CD2-CD1 3.28Å; F4-Y74 AromaticContact CD2-CD2 3.75Å; F4-Y74 HydrophobicContact CD2-CD2 3.75Å; F4-Y74 AromaticContact CD2-CE1 3.71Å; F4-Y74 HydrophobicContact CD2-CE1 3.71Å; F4-Y74 HydrophobicContact CD2-CE2 4.23Å; F4-Y74 AromaticContact CD2-CG 3.33Å; F4-Y74 HydrophobicContact CD2-CG 3.33Å; F4-Y74 AromaticContact CE2-CD1 3.92Å; F4-Y74 HydrophobicContact CE2-CD1 3.92Å; F4-Y74 AromaticContact CE2-CD2 3.49Å; F4-Y74 HydrophobicContact CE2-CD2 3.49Å; F4-Y74 VanDerWaalsContact CE2-CD2 3.49Å; F4-Y74 HydrophobicContact CE2-CE1 4.42Å; F4-Y74 HydrophobicContact CE2-CE2 4.14Å; F4-Y74 AromaticContact CE2-CG 3.45Å; F4-Y74 HydrophobicContact CE2-CG 3.45Å; F4-Y74 VanDerWaalsContact CE2-CG 3.45Å; F4-Y74 HydrophobicContact CG-CD1 4.13Å; F4-Y74 HydrophobicContact CG-CG 4.36Å; R35-Y74 VanDerWaalsContact CZ-OH 3.24Å; R35-Y74 PolarHBondContact NH1-OH 2.98Å; R35-Y74 PolarHBondContact NH2-OH 3.26Å; V38-Y74 HydrophobicContact CG1-CD2 4.31Å; E70-Y74 WeakPolarHBondContact O-CD2 3.4Å; F71-Y74 PolarHBondContact O-N 3.31Å; E72-Y74 PolarHBondContact O-N 2.84Å; E72-Y74 VanDerWaalsContact O-N 3.12Å
75L95.4Very high93.3Very high3 Ų348.9 Ų48.92%0.01627%0.268CS..Hα-helixtrans-121.1-20.5-178.7-57.9-179.8000113.8V38 A41 R42 L45 F71 S77 G78 Y79 L81 V103V38-L75 HydrophobicContact CG1-CD1 4.29Å; V38-L75 HydrophobicContact CG1-CG 4.19Å; A41-L75 HydrophobicContact CB-CD1 4.38Å; R42-L75 HydrophobicContact CB-CD2 3.62Å; R42-L75 HydrophobicContact CG-CD2 3.65Å; L45-L75 HydrophobicContact CD1-CD1 4.33Å; F71-L75 HydrophobicContact CD1-CD1 3.89Å; F71-L75 WeakPolarHBondContact O-CB 3.49Å; F71-L75 PolarHBondContact O-N 3.16Å; L75-S77 PolarHBondContact O-N 3.5Å; L75-S77 VanDerWaalsContact O-N 3.14Å; L75-G78 PolarHBondContact O-N 2.93Å; L75-Y79 HydrophobicContact CB-CD2 4.26Å; L75-Y79 HydrophobicContact CD2-CD2 4.31Å; L75-Y79 HydrophobicContact CD2-CE2 4.47Å; L75-Y79 PolarHBondContact O-N 3.15Å; L75-L81 HydrophobicContact CB-CD1 3.98Å; L75-L81 HydrophobicContact CB-CD2 4.15Å; L75-V103 HydrophobicContact CD1-CG2 4.36Å
76G92Very high92.6Very high37 Ų3748.7 Ų48.738%0.38127%0.272SS..THydrogen-bonded Turntrans-65.2-19.5-171.300000115.3E72E72-G76 WeakPolarHBondContact O-CA 3.32Å; E72-G76 PolarHBondContact O-N 3.42Å
77S91.9Very high91.5Very high110 Ų11052.1 Ų52.177%0.76929%0.29SS*.THydrogen-bonded Turntrans-79.2-20.1175.260.30000113.7L75L75-S77 PolarHBondContact O-N 3.5Å; L75-S77 VanDerWaalsContact O-N 3.14Å
78G93.3Very high90.7Very high55 Ų5551.4 Ų51.457%0.56729%0.291SS*.THydrogen-bonded Turntrans-116.2-18.3-17500000114.8L75L75-G78 PolarHBondContact O-N 2.93Å
79Y96.8Very high90.1Very high61 Ų6155.6 Ų55.624%0.23931%0.305CS..SBendtrans-139.5153.5-171-59.5-75.7000111.3L45 L75 L81 D102L45-Y79 HydrophobicContact CB-CD1 4.29Å; L45-Y79 HydrophobicContact CB-CE1 3.62Å; L45-Y79 HydrophobicContact CB-CE2 4.13Å; L45-Y79 HydrophobicContact CD1-CD1 4.15Å; L45-Y79 HydrophobicContact CD1-CD2 3.96Å; L45-Y79 HydrophobicContact CD1-CE1 4.26Å; L45-Y79 HydrophobicContact CD1-CE2 4.06Å; L45-Y79 HydrophobicContact CD1-CG 3.99Å; L45-Y79 HydrophobicContact CD2-CD1 4.11Å; L45-Y79 HydrophobicContact CD2-CE1 4.19Å; L45-Y79 HydrophobicContact CG-CD1 4.43Å; L45-Y79 HydrophobicContact CG-CE1 4.24Å; L75-Y79 HydrophobicContact CB-CD2 4.26Å; L75-Y79 HydrophobicContact CD2-CD2 4.31Å; L75-Y79 HydrophobicContact CD2-CE2 4.47Å; L75-Y79 PolarHBondContact O-N 3.15Å; Y79-L81 VanDerWaalsContact O-CD1 3.29Å; Y79-L81 WeakPolarHBondContact O-CD1 3.41Å; Y79-D102 WeakPolarHBondContact CA-OD2 3.41Å; Y79-D102 HydrophobicContact CD1-CB 4.26Å
80K97.3Very high89.9Confident132 Ų13255.4 Ų55.457%0.57431%0.306SS*.  trans-83.1116174.5-66.7180-178.71790110.3D100 N101 D102 V103K80-D100 VanDerWaalsContact CD-O 3.23Å; K80-D100 WeakPolarHBondContact CD-O 3.43Å; K80-N101 HydrophobicContact CB-CB 4.5Å; K80-D102 PolarHBondContact N-OD2 3.36Å; K80-D102 PolarHBondContact O-N 2.78Å; K80-V103 PolarHBondContact O-N 2.89Å; K80-V103 VanDerWaalsContact O-N 3.11Å
81L97.3Very high89.3Confident17 Ų1755.4 Ų55.49%0.08931%0.305CS..EExtended strand (participates in β ladder)trans-111.5130.4-177.6-85.362.7000110.6Y67 F71 E72 L75 Y79 V103Y67-L81 HydrophobicContact CE2-CB 3.75Å; Y67-L81 PolarHBondContact OH-O 2.94Å; F71-L81 VanDerWaalsContact C-CD2 3.49Å; F71-L81 HydrophobicContact CB-CD2 3.93Å; F71-L81 WeakPolarHBondContact O-CD2 3.33Å; E72-L81 HydrophobicContact CB-CD2 4.32Å; L75-L81 HydrophobicContact CB-CD1 3.98Å; L75-L81 HydrophobicContact CB-CD2 4.15Å; Y79-L81 VanDerWaalsContact O-CD1 3.29Å; Y79-L81 WeakPolarHBondContact O-CD1 3.41Å; L81-V103 WeakPolarHBondContact CA-O 3.43Å; L81-V103 HydrophobicContact CD1-CB 4.03Å; L81-V103 HydrophobicContact CD1-CG2 4.1Å; L81-V103 HydrophobicContact CG-CB 3.9Å; L81-V103 HydrophobicContact CG-CG1 4.32Å; L81-V103 HydrophobicContact CG-CG2 4.45Å
82M96Very high88.4Confident41 Ų4158.1 Ų58.120%0.20232%0.32CS..EExtended strand (participates in β ladder)trans-124141.5173.4-165.265.8-13200112.2V84 E90 V97 N101 V103 I104 I105M82-V84 HydrophobicContact CG-CG2 3.97Å; M82-E90 HydrophobicContact CE-CG 3.95Å; M82-V97 HydrophobicContact CB-CG1 4.15Å; M82-V97 HydrophobicContact CG-CG1 3.75Å; M82-N101 HydrophobicContact CB-CB 4.28Å; M82-V103 PolarHBondContact N-O 3.01Å; M82-I104 WeakPolarHBondContact O-CA 3.29Å; M82-I105 PolarHBondContact O-N 3.12Å
83K94.6Very high88Confident73 Ų7359.7 Ų59.732%0.31733%0.326SS..EExtended strand (participates in β ladder)trans-108.3130.7169.959.1178.3-172.4175.10110.6V63 D64 Y67 I105V63-K83 HydrophobicContact CG1-CB 3.66Å; D64-K83 WeakPolarHBondContact OD1-CD 3.32Å; D64-K83 WeakPolarHBondContact OD1-CE 3.44Å; D64-K83 IonicContact OD1-NZ 3.82Å; D64-K83 PolarHBondContact OD1-NZ 3.31Å; Y67-K83 HydrophobicContact CD1-CD 4.22Å; Y67-K83 HydrophobicContact CD2-CB 3.73Å; Y67-K83 HydrophobicContact CD2-CD 4.34Å; Y67-K83 HydrophobicContact CD2-CG 4.21Å; Y67-K83 HydrophobicContact CE2-CB 4.22Å; Y67-K83 HydrophobicContact CE2-CG 4.37Å; Y67-K83 HydrophobicContact CG-CB 4.16Å; Y67-K83 HydrophobicContact CG-CD 4.07Å; Y67-K83 HydrophobicContact CG-CG 4.44Å; K83-I105 WeakPolarHBondContact CA-O 3.34Å
84V91.8Very high87.9Confident0 Ų056.7 Ų56.70%031%0.306CS..EExtended strand (participates in β ladder)trans-133.8122-178.8-171.80000110.6M82 E90 K91 F94 V97 I104 I105 C106 I110M82-V84 HydrophobicContact CG-CG2 3.97Å; V84-E90 HydrophobicContact CG1-CB 4.46Å; V84-E90 HydrophobicContact CG2-CB 4.18Å; V84-K91 HydrophobicContact CG1-CB 3.91Å; V84-F94 HydrophobicContact CB-CD2 4.37Å; V84-F94 HydrophobicContact CB-CE2 4.05Å; V84-F94 HydrophobicContact CG1-CD2 4.02Å; V84-F94 HydrophobicContact CG1-CE2 4.14Å; V84-F94 HydrophobicContact CG2-CD2 4.22Å; V84-F94 HydrophobicContact CG2-CE2 4Å; V84-V97 HydrophobicContact CG2-CG1 4.09Å; V84-I104 HydrophobicContact CG2-CG2 4.33Å; V84-I105 PolarHBondContact N-O 3.27Å; V84-C106 HydrophobicContact CB-CB 4.1Å; V84-C106 WeakPolarHBondContact O-CA 3.49Å; V84-C106 VanDerWaalsContact O-CB 3.25Å; V84-C106 WeakPolarHBondContact O-CB 3.42Å; V84-I110 HydrophobicContact CG1-CG2 4.11Å
85S85.6Confident87.8Confident13 Ų1353.3 Ų53.39%0.09129%0.293CS..  trans-121.6-179.8174.881.60000111.5V60 D87 S88V60-S85 VanDerWaalsContact CG1-CB 3.5Å; S85-D87 PolarHBondContact O-N 2.61Å; S85-D87 VanDerWaalsContact O-N 3.14Å; S85-D87 PolarHBondContact OG-N 3.17Å; S85-S88 PolarHBondContact N-OG 3.37Å; S85-S88 WeakPolarHBondContact O-CB 3.3Å; S85-S88 PolarHBondContact O-N 3.1Å
86G74.1Confident87.6Confident17 Ų1756.3 Ų56.318%0.17531%0.309CS..THydrogen-bonded Turntrans-61.9-16174.100000114.4K91 R600G86-K91 PolarHBondContact O-NZ 3.29Å; G86-R600 PolarHBondContact O-NH1 3.27Å
87D69.4Low87.7Confident79 Ų7955.3 Ų55.342%0.42230%0.295SS..THydrogen-bonded Turntrans-104.6-11.7-175.6-62.4-5.2000112.4S85 Q419S85-D87 PolarHBondContact O-N 2.61Å; S85-D87 VanDerWaalsContact O-N 3.14Å; S85-D87 PolarHBondContact OG-N 3.17Å; D87-Q419 PolarHBondContact OD1-NE2 2.84Å; D87-Q419 PolarHBondContact OD2-NE2 2.92Å; D87-Q419 PolarHBondContact OD2-OE1 3.26Å; D87-Q419 VanDerWaalsContact OD2-OE1 3.04Å
88S77.3Confident87.9Confident24 Ų2450.2 Ų50.217%0.16826%0.259CS..  trans-67.6142.9172.6-66.70000111.9S85 E90 K91S85-S88 PolarHBondContact N-OG 3.37Å; S85-S88 WeakPolarHBondContact O-CB 3.3Å; S85-S88 PolarHBondContact O-N 3.1Å; S88-E90 VanDerWaalsContact C-N 3.3Å; S88-E90 WeakPolarHBondContact CB-OE2 3.47Å; S88-K91 WeakPolarHBondContact O-CD 3.39Å; S88-K91 VanDerWaalsContact O-CE 3.31Å; S88-K91 WeakPolarHBondContact O-CE 3.47Å; S88-K91 VanDerWaalsContact O-CG 3.26Å; S88-K91 WeakPolarHBondContact O-CG 3.41Å
89Q78.3Confident87.9Confident164 Ų16453.9 Ų53.977%0.76626%0.261SS*.SBendtrans-75.5-26.3170.6-68.9-176.9-7.200111K91 D92Q89-K91 PolarHBondContact O-N 2.88Å; Q89-K91 VanDerWaalsContact O-N 3.07Å; Q89-D92 WeakPolarHBondContact O-CB 3.46Å; Q89-D92 PolarHBondContact O-N 3.33Å
90E84.1Confident87.8Confident73 Ų7355.6 Ų55.634%0.34128%0.275SS..G310 helixtrans-59-22.4179.4-64.885.2171.500113M82 V84 S88 D92 F93 F94 V97M82-E90 HydrophobicContact CE-CG 3.95Å; V84-E90 HydrophobicContact CG1-CB 4.46Å; V84-E90 HydrophobicContact CG2-CB 4.18Å; S88-E90 VanDerWaalsContact C-N 3.3Å; S88-E90 WeakPolarHBondContact CB-OE2 3.47Å; E90-D92 PolarHBondContact O-N 2.72Å; E90-F93 CarbonylContact O-C 3.47Å; E90-F93 PolarHBondContact O-N 3.07Å; E90-F94 PolarHBondContact O-N 3.43Å; E90-V97 HydrophobicContact CB-CG2 3.99Å; E90-V97 WeakPolarHBondContact O-CG2 3.32Å
91K79.2Confident87.8Confident39 Ų3950.5 Ų50.517%0.1725%0.254CS..G310 helixtrans-63-26.5175.676.4-168.3172.5-159.10112.7V84 G86 S88 Q89 F93 F94 I110V84-K91 HydrophobicContact CG1-CB 3.91Å; G86-K91 PolarHBondContact O-NZ 3.29Å; S88-K91 WeakPolarHBondContact O-CD 3.39Å; S88-K91 VanDerWaalsContact O-CE 3.31Å; S88-K91 WeakPolarHBondContact O-CE 3.47Å; S88-K91 VanDerWaalsContact O-CG 3.26Å; S88-K91 WeakPolarHBondContact O-CG 3.41Å; Q89-K91 PolarHBondContact O-N 2.88Å; Q89-K91 VanDerWaalsContact O-N 3.07Å; K91-F93 PolarHBondContact O-N 3.32Å; K91-F94 WeakPolarHBondContact O-CB 3.12Å; K91-F94 PolarHBondContact O-N 2.89Å; K91-I110 HydrophobicContact CB-CD1 3.92Å
92D78.7Confident87.9Confident59 Ų5952.1 Ų52.132%0.31626%0.263SS..G310 helixtrans-80.2-11.7-174.5-58.4-42.1000111.4Q89 E90 K122Q89-D92 WeakPolarHBondContact O-CB 3.46Å; Q89-D92 PolarHBondContact O-N 3.33Å; E90-D92 PolarHBondContact O-N 2.72Å; D92-K122 WeakPolarHBondContact O-CE 3.32Å; D92-K122 WeakPolarHBondContact O-CG 3.43Å
93F86.9Confident88Confident117 Ų11750.2 Ų50.251%0.51325%0.253SS..G310 helixtrans-128.235.4174.1-57.6-81000110.8E90 K91 G95 I96 V97 A121E90-F93 CarbonylContact O-C 3.47Å; E90-F93 PolarHBondContact O-N 3.07Å; K91-F93 PolarHBondContact O-N 3.32Å; F93-G95 PolarHBondContact O-N 3.36Å; F93-G95 VanDerWaalsContact O-N 3.11Å; F93-I96 HydrophobicContact CB-CB 4.39Å; F93-I96 HydrophobicContact CB-CD1 4.29Å; F93-I96 HydrophobicContact CD1-CD1 4.15Å; F93-I96 WeakPolarHBondContact O-CB 3.44Å; F93-I96 PolarHBondContact O-N 3.45Å; F93-V97 WeakPolarHBondContact O-CG2 3.2Å; F93-V97 PolarHBondContact O-N 2.93Å; F93-A121 CarbonylContact C-O 3.52Å; F93-A121 WeakPolarHBondContact CA-O 3.45Å; F93-A121 HydrophobicContact CD1-CB 4.17Å
94F92.1Very high88.2Confident3 Ų346.8 Ų46.81%0.01324%0.238CC..Hα-helixtrans-59-30.2-168.9-167.6-109.5000113.4M54 V84 E90 K91 V97 V98 I104 C106 I110 L111 A114 V124M54-F94 HydrophobicContact CE-CE1 4.18Å; M54-F94 HydrophobicContact CE-CZ 3.88Å; M54-F94 HydrophobicContact SD-CZ 4.15Å; V84-F94 HydrophobicContact CB-CD2 4.37Å; V84-F94 HydrophobicContact CB-CE2 4.05Å; V84-F94 HydrophobicContact CG1-CD2 4.02Å; V84-F94 HydrophobicContact CG1-CE2 4.14Å; V84-F94 HydrophobicContact CG2-CD2 4.22Å; V84-F94 HydrophobicContact CG2-CE2 4Å; E90-F94 PolarHBondContact O-N 3.43Å; K91-F94 WeakPolarHBondContact O-CB 3.12Å; K91-F94 PolarHBondContact O-N 2.89Å; F94-V97 PolarHBondContact O-N 3.44Å; F94-V98 HydrophobicContact CD1-CG2 4.02Å; F94-V98 HydrophobicContact CE1-CG2 3.72Å; F94-V98 HydrophobicContact CE2-CG2 4.39Å; F94-V98 HydrophobicContact CZ-CG2 3.93Å; F94-V98 WeakPolarHBondContact O-CB 3.47Å; F94-V98 VanDerWaalsContact O-CG2 3.27Å; F94-V98 WeakPolarHBondContact O-CG2 3.22Å; F94-V98 PolarHBondContact O-N 3.37Å; F94-I104 HydrophobicContact CE2-CG2 3.97Å; F94-I104 HydrophobicContact CZ-CG2 4.16Å; F94-C106 HydrophobicContact CE2-CB 4.35Å; F94-C106 HydrophobicContact CZ-CB 4.42Å; F94-I110 HydrophobicContact CD1-CG2 4.1Å; F94-I110 HydrophobicContact CD2-CG2 3.52Å; F94-I110 HydrophobicContact CE1-CG2 4.09Å; F94-I110 HydrophobicContact CE2-CG2 3.52Å; F94-I110 HydrophobicContact CG-CG2 3.81Å; F94-I110 HydrophobicContact CZ-CG2 3.8Å; F94-L111 HydrophobicContact CE1-CD1 4.24Å; F94-A114 HydrophobicContact CD1-CB 3.52Å; F94-A114 HydrophobicContact CE1-CB 4.13Å; F94-A114 HydrophobicContact CG-CB 4.49Å; F94-V124 HydrophobicContact CD1-CG2 3.82Å; F94-V124 HydrophobicContact CE1-CG2 4.21Å
95G91.6Very high88.5Confident2 Ų246.8 Ų46.82%0.02124%0.238CC..Hα-helixtrans-62.1-47.6174.100000111.9F93 V98 Q99 A121 H123F93-G95 PolarHBondContact O-N 3.36Å; F93-G95 VanDerWaalsContact O-N 3.11Å; G95-V98 PolarHBondContact O-N 3.41Å; G95-Q99 WeakPolarHBondContact O-CG 3.26Å; G95-Q99 PolarHBondContact O-N 3.11Å; G95-A121 WeakPolarHBondContact CA-O 3.47Å; G95-A121 PolarHBondContact N-O 2.78Å; G95-H123 WeakPolarHBondContact CA-O 3.44Å
96I92.1Very high89Confident67 Ų6746.2 Ų46.234%0.34423%0.234SC..Hα-helixtrans-64-44.6176.4-56.6177.4000110.4F93 V98 Q99 D100 A121F93-I96 HydrophobicContact CB-CB 4.39Å; F93-I96 HydrophobicContact CB-CD1 4.29Å; F93-I96 HydrophobicContact CD1-CD1 4.15Å; F93-I96 WeakPolarHBondContact O-CB 3.44Å; F93-I96 PolarHBondContact O-N 3.45Å; I96-V98 VanDerWaalsContact C-N 3.28Å; I96-V98 PolarHBondContact O-N 2.77Å; I96-Q99 WeakPolarHBondContact O-CA 2.98Å; I96-Q99 WeakPolarHBondContact O-CB 3.43Å; I96-Q99 PolarHBondContact O-N 2.94Å; I96-D100 PolarHBondContact O-N 2.85Å; I96-A121 HydrophobicContact CD1-CB 4.15Å; I96-A121 PolarHBondContact N-O 2.72Å
97V94Very high90Very high16 Ų1646.2 Ų46.210%0.09723%0.231CC..Hα-helixtrans-58.5-42.9177.3172.20000111.3M82 V84 E90 F93 F94 Q99 D100 N101M82-V97 HydrophobicContact CB-CG1 4.15Å; M82-V97 HydrophobicContact CG-CG1 3.75Å; V84-V97 HydrophobicContact CG2-CG1 4.09Å; E90-V97 HydrophobicContact CB-CG2 3.99Å; E90-V97 WeakPolarHBondContact O-CG2 3.32Å; F93-V97 WeakPolarHBondContact O-CG2 3.2Å; F93-V97 PolarHBondContact O-N 2.93Å; F94-V97 PolarHBondContact O-N 3.44Å; V97-Q99 VanDerWaalsContact C-N 3.34Å; V97-D100 PolarHBondContact O-N 2.85Å; V97-N101 WeakPolarHBondContact O-CB 3.25Å; V97-N101 PolarHBondContact O-N 3.2Å; V97-N101 PolarHBondContact O-ND2 3.06Å
98V95.6Very high91.2Very high2 Ų242.8 Ų42.81%0.01221%0.213CC..Hα-helixtrans-63.1-43.1175.3168.80000110K52 M54 F94 G95 I96 D100 I104 V124K52-V98 HydrophobicContact CD-CG1 3.71Å; K52-V98 VanDerWaalsContact CD-O 3.27Å; K52-V98 WeakPolarHBondContact CD-O 3.35Å; K52-V98 VanDerWaalsContact CE-O 3.31Å; K52-V98 WeakPolarHBondContact CE-O 3.38Å; K52-V98 PolarHBondContact NZ-O 3.07Å; M54-V98 HydrophobicContact CE-CG2 3.68Å; F94-V98 HydrophobicContact CD1-CG2 4.02Å; F94-V98 HydrophobicContact CE1-CG2 3.72Å; F94-V98 HydrophobicContact CE2-CG2 4.39Å; F94-V98 HydrophobicContact CZ-CG2 3.93Å; F94-V98 WeakPolarHBondContact O-CB 3.47Å; F94-V98 VanDerWaalsContact O-CG2 3.27Å; F94-V98 WeakPolarHBondContact O-CG2 3.22Å; F94-V98 PolarHBondContact O-N 3.37Å; G95-V98 PolarHBondContact O-N 3.41Å; I96-V98 VanDerWaalsContact C-N 3.28Å; I96-V98 PolarHBondContact O-N 2.77Å; V98-D100 PolarHBondContact O-N 3.33Å; V98-I104 HydrophobicContact CG2-CD1 4.46Å; V98-V124 HydrophobicContact CB-CG2 4.12Å; V98-V124 HydrophobicContact CG1-CG1 4.32Å; V98-V124 HydrophobicContact CG1-CG2 4.43Å; V98-V124 HydrophobicContact CG2-CG2 3.89Å
99Q93.4Very high91.9Very high132 Ų13245.5 Ų45.562%0.61722%0.223SC*.Hα-helixtrans-61.2-44177.9-70.9174.32.100113K52 G95 I96 V97 N101K52-Q99 PolarHBondContact NZ-O 2.93Å; G95-Q99 WeakPolarHBondContact O-CG 3.26Å; G95-Q99 PolarHBondContact O-N 3.11Å; I96-Q99 WeakPolarHBondContact O-CA 2.98Å; I96-Q99 WeakPolarHBondContact O-CB 3.43Å; I96-Q99 PolarHBondContact O-N 2.94Å; V97-Q99 VanDerWaalsContact C-N 3.34Å; Q99-N101 PolarHBondContact O-N 3.05Å
100D95.3Very high92.6Very high98 Ų9838.5 Ų38.552%0.52419%0.191SC..Hα-helixtrans-80.9-12.7-171.7-73.7-18.8000115.6K80 I96 V97 V98K80-D100 VanDerWaalsContact CD-O 3.23Å; K80-D100 WeakPolarHBondContact CD-O 3.43Å; I96-D100 PolarHBondContact O-N 2.85Å; V97-D100 PolarHBondContact O-N 2.85Å; V98-D100 PolarHBondContact O-N 3.33Å
101N97.4Very high93.1Very high25 Ų2535 Ų3513%0.13418%0.175CC..  trans-120.4149.9-174.6-65-84.7000112.5K52 K80 M82 V97 Q99 I104K52-N101 WeakPolarHBondContact CE-O 3.17Å; K52-N101 PolarHBondContact NZ-O 3.14Å; K80-N101 HydrophobicContact CB-CB 4.5Å; M82-N101 HydrophobicContact CB-CB 4.28Å; V97-N101 WeakPolarHBondContact O-CB 3.25Å; V97-N101 PolarHBondContact O-N 3.2Å; V97-N101 PolarHBondContact O-ND2 3.06Å; Q99-N101 PolarHBondContact O-N 3.05Å; N101-I104 HydrophobicContact CB-CD1 4.09Å; N101-I104 HydrophobicContact CB-CG1 4.08Å
102D98.1Very high93.9Very high51 Ų5135.1 Ų35.127%0.27318%0.175SC..SBendtrans-87.3-36.1179.3-54.2-54.9000111.3L45 V53 Y79 K80L45-D102 HydrophobicContact CD2-CB 4.09Å; V53-D102 PolarHBondContact N-O 2.89Å; Y79-D102 WeakPolarHBondContact CA-OD2 3.41Å; Y79-D102 HydrophobicContact CD1-CB 4.26Å; K80-D102 PolarHBondContact N-OD2 3.36Å; K80-D102 PolarHBondContact O-N 2.78Å
103V98.5Very high94.5Very high1 Ų136.2 Ų36.21%0.00618%0.18CC..EExtended strand (participates in β ladder)trans-130.7124-178-176.40000110.1L45 V53 F71 L75 K80 L81 M82L45-V103 HydrophobicContact CD1-CG2 3.69Å; L45-V103 HydrophobicContact CD2-CG2 4.39Å; V53-V103 HydrophobicContact CB-CG1 4.41Å; V53-V103 HydrophobicContact CB-CG2 4.19Å; V53-V103 CarbonylContact O-C 3.38Å; V53-V103 WeakPolarHBondContact O-CA 3.42Å; F71-V103 HydrophobicContact CD1-CG1 3.92Å; F71-V103 HydrophobicContact CE1-CG1 4.32Å; L75-V103 HydrophobicContact CD1-CG2 4.36Å; K80-V103 PolarHBondContact O-N 2.89Å; K80-V103 VanDerWaalsContact O-N 3.11Å; L81-V103 WeakPolarHBondContact CA-O 3.43Å; L81-V103 HydrophobicContact CD1-CB 4.03Å; L81-V103 HydrophobicContact CD1-CG2 4.1Å; L81-V103 HydrophobicContact CG-CB 3.9Å; L81-V103 HydrophobicContact CG-CG1 4.32Å; L81-V103 HydrophobicContact CG-CG2 4.45Å; M82-V103 PolarHBondContact N-O 3.01Å
104I98.3Very high94.8Very high0 Ų031 Ų310%016%0.158CC..EExtended strand (participates in β ladder)trans-121.7125.1179.4-57.489.7000109.3K52 V53 M54 V55 M82 V84 F94 V98 N101 C106K52-I104 HydrophobicContact CG-CD1 4.43Å; V53-I104 PolarHBondContact O-N 2.99Å; M54-I104 CarbonylContact C-O 3.49Å; M54-I104 WeakPolarHBondContact CA-O 3.49Å; M54-I104 HydrophobicContact CE-CB 4Å; M54-I104 HydrophobicContact CE-CD1 4.44Å; M54-I104 HydrophobicContact CE-CG2 4.22Å; M54-I104 HydrophobicContact SD-CB 3.78Å; M54-I104 HydrophobicContact SD-CG2 3.82Å; V55-I104 PolarHBondContact N-O 3.19Å; M82-I104 WeakPolarHBondContact O-CA 3.29Å; V84-I104 HydrophobicContact CG2-CG2 4.33Å; F94-I104 HydrophobicContact CE2-CG2 3.97Å; F94-I104 HydrophobicContact CZ-CG2 4.16Å; V98-I104 HydrophobicContact CG2-CD1 4.46Å; N101-I104 HydrophobicContact CB-CD1 4.09Å; N101-I104 HydrophobicContact CB-CG1 4.08Å; I104-C106 HydrophobicContact CG2-CB 4.46Å
105I98.3Very high94.8Very high1 Ų132 Ų321%0.00516%0.164CC..EExtended strand (participates in β ladder)trans-107.3118.2173.6-51.3177.7000108V55 V63 H66 Y67 F71 M82 K83 V84V55-I105 HydrophobicContact CB-CB 4.37Å; V55-I105 HydrophobicContact CB-CG1 4.06Å; V55-I105 HydrophobicContact CB-CG2 4.26Å; V55-I105 HydrophobicContact CG1-CG2 4.39Å; V55-I105 HydrophobicContact CG2-CG1 4.16Å; V55-I105 WeakPolarHBondContact O-CA 3.44Å; V63-I105 HydrophobicContact CG1-CG2 4.22Å; H66-I105 HydrophobicContact CB-CD1 4.43Å; Y67-I105 HydrophobicContact CD2-CD1 4.14Å; F71-I105 HydrophobicContact CB-CD1 3.7Å; F71-I105 HydrophobicContact CD1-CD1 4.37Å; F71-I105 HydrophobicContact CD2-CD1 3.69Å; F71-I105 HydrophobicContact CE2-CD1 4.43Å; F71-I105 HydrophobicContact CG-CD1 3.66Å; M82-I105 PolarHBondContact O-N 3.12Å; K83-I105 WeakPolarHBondContact CA-O 3.34Å; V84-I105 PolarHBondContact N-O 3.27Å
106C96.9Very high94.7Very high0 Ų036.7 Ų36.70%019%0.188CC..EExtended strand (participates in β ladder)trans-146.4162.1-177.772.60000114M54 V55 L56 V57 V84 F94 I104 I110M54-C106 VanDerWaalsContact SD-SG 3.64Å; V55-C106 PolarHBondContact O-N 2.87Å; L56-C106 WeakPolarHBondContact CA-O 3.47Å; V57-C106 PolarHBondContact N-O 2.81Å; V84-C106 HydrophobicContact CB-CB 4.1Å; V84-C106 WeakPolarHBondContact O-CA 3.49Å; V84-C106 VanDerWaalsContact O-CB 3.25Å; V84-C106 WeakPolarHBondContact O-CB 3.42Å; F94-C106 HydrophobicContact CE2-CB 4.35Å; F94-C106 HydrophobicContact CZ-CB 4.42Å; I104-C106 HydrophobicContact CG2-CB 4.46Å; C106-I110 HydrophobicContact CB-CB 4.43Å
107T93.8Very high94.4Very high17 Ų1735.7 Ų35.710%0.10418%0.183CC..EExtended strand (participates in β ladder)trans-70.9140.6168.458.70000110.5V57 V60 V63 Q109 I110V57-T107 HydrophobicContact CG2-CG2 4.27Å; V57-T107 WeakPolarHBondContact O-CA 3.5Å; V60-T107 HydrophobicContact CB-CG2 4.43Å; V60-T107 HydrophobicContact CG2-CG2 3.83Å; V63-T107 HydrophobicContact CG2-CG2 3.95Å; T107-Q109 PolarHBondContact O-N 2.79Å; T107-I110 WeakPolarHBondContact O-CB 3.37Å; T107-I110 PolarHBondContact O-N 2.92Å; T107-I110 WeakPolarHBondContact OG1-CG1 3.42Å
108A95.4Very high93.9Very high7 Ų744.4 Ų44.46%0.05822%0.22CC..Hα-helixtrans-47.8-37.2-177.200000115V57 I110 L111 Y112 V145 Y146 I149V57-A108 PolarHBondContact O-N 3.46Å; V57-A108 VanDerWaalsContact O-N 3.1Å; A108-I110 PolarHBondContact O-N 2.9Å; A108-L111 PolarHBondContact O-N 3.41Å; A108-Y112 PolarHBondContact O-N 3.41Å; A108-V145 HydrophobicContact CB-CB 4.01Å; A108-V145 HydrophobicContact CB-CG1 3.67Å; A108-Y146 HydrophobicContact CB-CD1 3.49Å; A108-Y146 VanDerWaalsContact CB-CD1 3.49Å; A108-Y146 HydrophobicContact CB-CE1 3.44Å; A108-Y146 VanDerWaalsContact CB-CE1 3.44Å; A108-I149 HydrophobicContact CB-CD1 4.28Å; A108-I149 WeakPolarHBondContact O-CD1 3.47Å
109Q91.6Very high93.3Very high81 Ų8149.3 Ų49.338%0.37924%0.243SC..Hα-helixtrans-64.1-29.7-177.2-170.164.75600112.5T107 N113 V145T107-Q109 PolarHBondContact O-N 2.79Å; Q109-N113 PolarHBondContact NE2-OD1 3.12Å; Q109-N113 WeakPolarHBondContact O-CB 3.46Å; Q109-N113 PolarHBondContact O-N 2.75Å; Q109-N113 PolarHBondContact O-OD1 3.02Å; Q109-V145 VanDerWaalsContact OE1-CG2 3.22Å
110I92.6Very high92.7Very high17 Ų1751.5 Ų51.59%0.08725%0.253CS..Hα-helixtrans-65.7-51.9177.6-60.6-66.5000109.7V84 K91 F94 C106 T107 A108 Y112 N113 A114V84-I110 HydrophobicContact CG1-CG2 4.11Å; K91-I110 HydrophobicContact CB-CD1 3.92Å; F94-I110 HydrophobicContact CD1-CG2 4.1Å; F94-I110 HydrophobicContact CD2-CG2 3.52Å; F94-I110 HydrophobicContact CE1-CG2 4.09Å; F94-I110 HydrophobicContact CE2-CG2 3.52Å; F94-I110 HydrophobicContact CG-CG2 3.81Å; F94-I110 HydrophobicContact CZ-CG2 3.8Å; C106-I110 HydrophobicContact CB-CB 4.43Å; T107-I110 WeakPolarHBondContact O-CB 3.37Å; T107-I110 PolarHBondContact O-N 2.92Å; T107-I110 WeakPolarHBondContact OG1-CG1 3.42Å; A108-I110 PolarHBondContact O-N 2.9Å; I110-Y112 VanDerWaalsContact C-N 3.35Å; I110-Y112 PolarHBondContact O-N 3.34Å; I110-N113 PolarHBondContact O-N 2.86Å; I110-A114 PolarHBondContact O-N 3.26Å
111L96.3Very high92.2Very high0 Ų048.4 Ų48.40%024%0.241CC..Hα-helixtrans-60.8-44.5175.917961.7000111.4M54 L56 F94 A108 N113 A114 L115 V124 I129 L132 I149M54-L111 HydrophobicContact CE-CD1 4.47Å; M54-L111 HydrophobicContact CG-CD2 4.21Å; L56-L111 HydrophobicContact CD1-CD2 4.06Å; L56-L111 HydrophobicContact CD2-CB 4.06Å; L56-L111 HydrophobicContact CD2-CD2 3.85Å; L56-L111 HydrophobicContact CG-CD2 4.45Å; F94-L111 HydrophobicContact CE1-CD1 4.24Å; A108-L111 PolarHBondContact O-N 3.41Å; L111-N113 VanDerWaalsContact C-N 3.3Å; L111-N113 PolarHBondContact O-N 3.24Å; L111-A114 PolarHBondContact O-N 3.39Å; L111-A114 VanDerWaalsContact O-N 3.15Å; L111-L115 HydrophobicContact CD1-CD2 4.46Å; L111-L115 HydrophobicContact CD1-CG 4.21Å; L111-L115 HydrophobicContact CG-CD1 4.22Å; L111-L115 HydrophobicContact CG-CG 4.29Å; L111-L115 VanDerWaalsContact O-CG 3.32Å; L111-L115 WeakPolarHBondContact O-CG 3.31Å; L111-L115 PolarHBondContact O-N 3.06Å; L111-V124 HydrophobicContact CD1-CG1 4.13Å; L111-I129 HydrophobicContact CD1-CD1 3.98Å; L111-I129 HydrophobicContact CD2-CD1 4.1Å; L111-L132 HydrophobicContact CD2-CD1 4.12Å; L111-I149 HydrophobicContact CB-CD1 4.39Å; L111-I149 HydrophobicContact CD2-CD1 4.28Å; L111-I149 HydrophobicContact CD2-CG2 4.21Å; L111-I149 HydrophobicContact CG-CD1 4.45Å
112Y95.3Very high91.8Very high42 Ų4249.7 Ų49.717%0.16525%0.245CC..Hα-helixtrans-61.3-39.1179.3-176.2-115.1000112.7A108 I110 L116 V145 K148 I149A108-Y112 PolarHBondContact O-N 3.41Å; I110-Y112 VanDerWaalsContact C-N 3.35Å; I110-Y112 PolarHBondContact O-N 3.34Å; Y112-L116 HydrophobicContact CD1-CD1 4.24Å; Y112-L116 HydrophobicContact CE1-CD1 3.64Å; Y112-L116 HydrophobicContact CE2-CD1 4.08Å; Y112-L116 HydrophobicContact CE2-CG 4.31Å; Y112-L116 WeakPolarHBondContact O-CG 3.48Å; Y112-L116 PolarHBondContact O-N 3.06Å; Y112-V145 HydrophobicContact CD1-CG1 4.49Å; Y112-V145 HydrophobicContact CG-CG1 4.2Å; Y112-K148 HydrophobicContact CD2-CB 3.95Å; Y112-K148 HydrophobicContact CE1-CD 3.85Å; Y112-K148 HydrophobicContact CE2-CB 3.56Å; Y112-K148 HydrophobicContact CE2-CD 4.22Å; Y112-K148 HydrophobicContact CE2-CG 4.44Å; Y112-I149 HydrophobicContact CD2-CG1 4.08Å; Y112-I149 HydrophobicContact CG-CG1 4.43Å
113N90.8Very high91.5Very high82 Ų8250.2 Ų50.244%0.43925%0.246SC..Hα-helixtrans-64.5-43174.3-71.6-5.3000111.4Q109 I110 L111 L115 L116 N117Q109-N113 PolarHBondContact NE2-OD1 3.12Å; Q109-N113 WeakPolarHBondContact O-CB 3.46Å; Q109-N113 PolarHBondContact O-N 2.75Å; Q109-N113 PolarHBondContact O-OD1 3.02Å; I110-N113 PolarHBondContact O-N 2.86Å; L111-N113 VanDerWaalsContact C-N 3.3Å; L111-N113 PolarHBondContact O-N 3.24Å; N113-L115 PolarHBondContact O-N 2.9Å; N113-L116 PolarHBondContact O-N 3.07Å; N113-L116 VanDerWaalsContact O-N 3.16Å; N113-N117 WeakPolarHBondContact O-CB 3.49Å; N113-N117 PolarHBondContact O-N 3.32Å
114A93.1Very high91.3Very high6 Ų650.2 Ų50.25%0.0525%0.246CC..Hα-helixtrans-63.4-39.3178.600000113F94 I110 L111 L116 N117 K122 H123 V124F94-A114 HydrophobicContact CD1-CB 3.52Å; F94-A114 HydrophobicContact CE1-CB 4.13Å; F94-A114 HydrophobicContact CG-CB 4.49Å; I110-A114 PolarHBondContact O-N 3.26Å; L111-A114 PolarHBondContact O-N 3.39Å; L111-A114 VanDerWaalsContact O-N 3.15Å; A114-L116 PolarHBondContact O-N 2.97Å; A114-N117 PolarHBondContact O-N 2.94Å; A114-K122 VanDerWaalsContact CB-O 3.31Å; A114-K122 WeakPolarHBondContact CB-O 3.46Å; A114-H123 PolarHBondContact O-ND1 2.78Å; A114-V124 HydrophobicContact CB-CB 4.05Å; A114-V124 HydrophobicContact CB-CG2 3.95Å; A114-V124 PolarHBondContact O-N 2.9Å
115L93.7Very high91.1Very high24 Ų2453 Ų5313%0.12626%0.259CS..Hα-helixtrans-62.5-25.1174.6-69.3173.7000113.3L111 N113 V124 L126 I149L111-L115 HydrophobicContact CD1-CD2 4.46Å; L111-L115 HydrophobicContact CD1-CG 4.21Å; L111-L115 HydrophobicContact CG-CD1 4.22Å; L111-L115 HydrophobicContact CG-CG 4.29Å; L111-L115 VanDerWaalsContact O-CG 3.32Å; L111-L115 WeakPolarHBondContact O-CG 3.31Å; L111-L115 PolarHBondContact O-N 3.06Å; N113-L115 PolarHBondContact O-N 2.9Å; L115-V124 WeakPolarHBondContact CD2-O 3.36Å; L115-L126 HydrophobicContact CD1-CD2 4.28Å; L115-L126 HydrophobicContact CD2-CD2 4.07Å; L115-L126 HydrophobicContact CD2-CG 3.87Å; L115-I149 HydrophobicContact CD1-CB 4.5Å; L115-I149 HydrophobicContact CD1-CG1 4.18Å; L115-I149 HydrophobicContact CD1-CG2 4.12Å
116L88.5Confident91Very high102 Ų10253 Ų5353%0.53426%0.259SS..Hα-helixtrans-98.9-17.3-179.7-64.8-179000113.4Y112 N113 A114Y112-L116 HydrophobicContact CD1-CD1 4.24Å; Y112-L116 HydrophobicContact CE1-CD1 3.64Å; Y112-L116 HydrophobicContact CE2-CD1 4.08Å; Y112-L116 HydrophobicContact CE2-CG 4.31Å; Y112-L116 WeakPolarHBondContact O-CG 3.48Å; Y112-L116 PolarHBondContact O-N 3.06Å; N113-L116 PolarHBondContact O-N 3.07Å; N113-L116 VanDerWaalsContact O-N 3.16Å; A114-L116 PolarHBondContact O-N 2.97Å
117N85.1Confident91Very high45 Ų4555 Ų5524%0.24127%0.274CS..  trans-72.6146.3-176.3-157.2-46.7000110.3N113 A114 E119 K122 H123N113-N117 WeakPolarHBondContact O-CB 3.49Å; N113-N117 PolarHBondContact O-N 3.32Å; A114-N117 PolarHBondContact O-N 2.94Å; N117-E119 WeakPolarHBondContact OD1-CB 3.4Å; N117-E119 PolarHBondContact OD1-N 2.93Å; N117-K122 HydrophobicContact CB-CB 4.19Å; N117-K122 WeakPolarHBondContact ND2-CD 3.3Å; N117-H123 PolarHBondContact O-ND1 2.94Å
118K83.4Confident91Very high199 Ų19957.8 Ų57.887%0.86529%0.288SS*.  trans-104-15.2177.4-62.5-178.2-178.81760113.1E120K118-E120 PolarHBondContact O-N 3.31Å
119E83.3Confident91.2Very high106 Ų10657.6 Ų57.650%0.49529%0.286SS..SBendtrans-70.7123174.9-66.6169.8-14600109.6N117 A121 K122 H123N117-E119 WeakPolarHBondContact OD1-CB 3.4Å; N117-E119 PolarHBondContact OD1-N 2.93Å; E119-A121 VanDerWaalsContact C-N 3.26Å; E119-A121 PolarHBondContact O-N 2.98Å; E119-K122 HydrophobicContact CB-CB 4.49Å; E119-K122 PolarHBondContact O-N 2.8Å; E119-K122 IonicContact OE1-NZ 3.73Å; E119-K122 WeakPolarHBondContact OE2-CD 3.45Å; E119-K122 WeakPolarHBondContact OE2-CE 3.42Å; E119-K122 IonicContact OE2-NZ 3.87Å; E119-K122 PolarHBondContact OE2-NZ 2.9Å; E119-H123 WeakPolarHBondContact O-CB 3.46Å; E119-H123 PolarHBondContact O-N 2.9Å
120E82.1Confident91.5Very high177 Ų17755.4 Ų55.483%0.82728%0.278SS*.THydrogen-bonded Turntrans-54.8-40.2-175.1-172.4174.1-171.400112.8K118 K122 H123K118-E120 PolarHBondContact O-N 3.31Å; E120-K122 PolarHBondContact O-N 3.36Å; E120-H123 PolarHBondContact O-N 3Å
121A85Confident91.8Very high33 Ų3354.6 Ų54.627%0.27327%0.274SS..THydrogen-bonded Turntrans-64.2-21.7179.500000114.3F93 G95 I96 E119F93-A121 CarbonylContact C-O 3.52Å; F93-A121 WeakPolarHBondContact CA-O 3.45Å; F93-A121 HydrophobicContact CD1-CB 4.17Å; G95-A121 WeakPolarHBondContact CA-O 3.47Å; G95-A121 PolarHBondContact N-O 2.78Å; I96-A121 HydrophobicContact CD1-CB 4.15Å; I96-A121 PolarHBondContact N-O 2.72Å; E119-A121 VanDerWaalsContact C-N 3.26Å; E119-A121 PolarHBondContact O-N 2.98Å
122K87.2Confident91.9Very high52 Ų5254.6 Ų54.623%0.22627%0.274CS..THydrogen-bonded Turntrans-109.7-22.6-177.8-70.3173.5-172.6153.20112.9D92 A114 N117 E119 E120D92-K122 WeakPolarHBondContact O-CE 3.32Å; D92-K122 WeakPolarHBondContact O-CG 3.43Å; A114-K122 VanDerWaalsContact CB-O 3.31Å; A114-K122 WeakPolarHBondContact CB-O 3.46Å; N117-K122 HydrophobicContact CB-CB 4.19Å; N117-K122 WeakPolarHBondContact ND2-CD 3.3Å; E119-K122 HydrophobicContact CB-CB 4.49Å; E119-K122 PolarHBondContact O-N 2.8Å; E119-K122 IonicContact OE1-NZ 3.73Å; E119-K122 WeakPolarHBondContact OE2-CD 3.45Å; E119-K122 WeakPolarHBondContact OE2-CE 3.42Å; E119-K122 IonicContact OE2-NZ 3.87Å; E119-K122 PolarHBondContact OE2-NZ 2.9Å; E120-K122 PolarHBondContact O-N 3.36Å
123H92.5Very high92.1Very high63 Ų6352.7 Ų52.729%0.29227%0.266SS..  trans-69.9140.6-172.9-176.465.3000111.7G95 A114 N117 E119 E120 E125G95-H123 WeakPolarHBondContact CA-O 3.44Å; A114-H123 PolarHBondContact O-ND1 2.78Å; N117-H123 PolarHBondContact O-ND1 2.94Å; E119-H123 WeakPolarHBondContact O-CB 3.46Å; E119-H123 PolarHBondContact O-N 2.9Å; E120-H123 PolarHBondContact O-N 3Å; H123-E125 IonicContact CE1-OE1 3.78Å; H123-E125 IonicContact NE2-OE1 3.16Å; H123-E125 PolarHBondContact NE2-OE1 2.91Å
124V94.5Very high92.4Very high1 Ų148.8 Ų48.81%0.00625%0.245CC..  trans-138138.8173.9174.80000107.3F94 V98 L111 A114 L115 D128F94-V124 HydrophobicContact CD1-CG2 3.82Å; F94-V124 HydrophobicContact CE1-CG2 4.21Å; V98-V124 HydrophobicContact CB-CG2 4.12Å; V98-V124 HydrophobicContact CG1-CG1 4.32Å; V98-V124 HydrophobicContact CG1-CG2 4.43Å; V98-V124 HydrophobicContact CG2-CG2 3.89Å; L111-V124 HydrophobicContact CD1-CG1 4.13Å; A114-V124 HydrophobicContact CB-CB 4.05Å; A114-V124 HydrophobicContact CB-CG2 3.95Å; A114-V124 PolarHBondContact O-N 2.9Å; L115-V124 WeakPolarHBondContact CD2-O 3.36Å; V124-D128 HydrophobicContact CG1-CB 4.45Å
125E94.8Very high92.6Very high58 Ų5848.8 Ų48.827%0.27124%0.244SC..  trans-102151.3169.2-82.1-67.3164.500111H123 S127 D128 K156H123-E125 IonicContact CE1-OE1 3.78Å; H123-E125 IonicContact NE2-OE1 3.16Å; H123-E125 PolarHBondContact NE2-OE1 2.91Å; E125-S127 PolarHBondContact O-N 2.78Å; E125-S127 VanDerWaalsContact O-N 3.14Å; E125-D128 PolarHBondContact N-OD2 2.77Å; E125-D128 WeakPolarHBondContact O-CB 3.5Å; E125-D128 PolarHBondContact O-N 2.77Å; E125-K156 IonicContact OE1-NZ 3.87Å; E125-K156 IonicContact OE2-NZ 2.75Å; E125-K156 PolarHBondContact OE2-NZ 2.97Å
126L96.1Very high92.7Very high0 Ų048 Ų480%024%0.24CC..G310 helixtrans-60-27.2174.4-74.7175.8000112L115 D128 I129 I149 C152 K156 P165L115-L126 HydrophobicContact CD1-CD2 4.28Å; L115-L126 HydrophobicContact CD2-CD2 4.07Å; L115-L126 HydrophobicContact CD2-CG 3.87Å; L126-D128 PolarHBondContact O-N 2.84Å; L126-I129 PolarHBondContact O-N 3.44Å; L126-I149 HydrophobicContact CD2-CG2 4.39Å; L126-C152 HydrophobicContact CD1-CB 4.16Å; L126-K156 HydrophobicContact CB-CD 4.42Å; L126-K156 HydrophobicContact CD1-CD 4.17Å; L126-P165 WeakPolarHBondContact O-CD 3.33Å
127S95.2Very high93.1Very high44 Ų4443.2 Ų43.231%0.30822%0.215SC..G310 helixtrans-69.3-15176.150.60000114.3E125 R163E125-S127 PolarHBondContact O-N 2.78Å; E125-S127 VanDerWaalsContact O-N 3.14Å; S127-R163 WeakPolarHBondContact CB-O 3.44Å
128D95.6Very high93.6Very high75 Ų7541.2 Ų41.240%0.40120%0.204SC..G310 helixtrans-77.9-14.3175.1-54.8-29.6000111.3K52 V124 E125 L126K52-D128 VanDerWaalsContact CB-O 3.23Å; K52-D128 WeakPolarHBondContact CB-O 3.33Å; K52-D128 WeakPolarHBondContact CD-O 3.41Å; K52-D128 WeakPolarHBondContact CG-O 3.37Å; V124-D128 HydrophobicContact CG1-CB 4.45Å; E125-D128 PolarHBondContact N-OD2 2.77Å; E125-D128 WeakPolarHBondContact O-CB 3.5Å; E125-D128 PolarHBondContact O-N 2.77Å; L126-D128 PolarHBondContact O-N 2.84Å
129I97.9Very high94.1Very high3 Ų334.1 Ų34.12%0.01517%0.174CC..  trans-105134-179-53.2170.7000108.4M54 L111 L126 L131 L132 P165M54-I129 HydrophobicContact CB-CD1 4.02Å; M54-I129 HydrophobicContact CB-CG1 4.37Å; M54-I129 HydrophobicContact CB-CG2 3.77Å; M54-I129 HydrophobicContact CE-CD1 4.14Å; M54-I129 HydrophobicContact CG-CD1 4.18Å; L111-I129 HydrophobicContact CD1-CD1 3.98Å; L111-I129 HydrophobicContact CD2-CD1 4.1Å; L126-I129 PolarHBondContact O-N 3.44Å; I129-L131 WeakPolarHBondContact CG2-O 3.36Å; I129-L132 HydrophobicContact CG2-CB 4.45Å; I129-P165 HydrophobicContact CB-CB 4.22Å; I129-P165 HydrophobicContact CB-CG 4.48Å; I129-P165 HydrophobicContact CG2-CB 3.96Å; I129-P165 WeakPolarHBondContact O-CB 3.48Å
130T98.2Very high94.7Very high35 Ų3529.1 Ų29.122%0.21515%0.151CC..SBendtrans-103.5-26.8177.363.80000112.9H44 K52 P165 Q166H44-T130 WeakPolarHBondContact NE2-CB 3.37Å; H44-T130 PolarHBondContact NE2-OG1 2.95Å; K52-T130 PolarHBondContact N-OG1 3.12Å; K52-T130 PolarHBondContact O-N 3.02Å; K52-T130 PolarHBondContact O-OG1 2.98Å; T130-P165 WeakPolarHBondContact O-CA 3.42Å; T130-Q166 PolarHBondContact O-N 3.41Å
131L98.8Very high95.2Very high0 Ų023.2 Ų23.20%012%0.123CC..EExtended strand (participates in β ladder)trans-139.6124.2174.3173.964.4000109.6V40 A41 H44 K52 V53 M54 I129 I133 Q166 L168V40-L131 HydrophobicContact CG1-CD2 4.25Å; A41-L131 HydrophobicContact CB-CD2 4.47Å; H44-L131 HydrophobicContact CB-CD2 3.92Å; K52-L131 PolarHBondContact O-N 3.03Å; K52-L131 VanDerWaalsContact O-N 3.09Å; V53-L131 WeakPolarHBondContact CA-O 3.33Å; V53-L131 HydrophobicContact CG1-CB 4.5Å; V53-L131 HydrophobicContact CG1-CD2 4.09Å; V53-L131 HydrophobicContact CG1-CG 4.33Å; V53-L131 HydrophobicContact CG2-CB 4.28Å; V53-L131 HydrophobicContact CG2-CD2 4.22Å; M54-L131 PolarHBondContact N-O 2.98Å; I129-L131 WeakPolarHBondContact CG2-O 3.36Å; L131-I133 HydrophobicContact CD1-CG1 4.46Å; L131-I133 HydrophobicContact CD2-CD1 4.11Å; L131-I133 HydrophobicContact CD2-CG1 4.17Å; L131-I133 HydrophobicContact CG-CD1 4.48Å; L131-I133 HydrophobicContact CG-CG1 4Å; L131-Q166 CarbonylContact C-O 3.52Å; L131-Q166 WeakPolarHBondContact CA-O 3.49Å; L131-Q166 HydrophobicContact CD1-CB 3.94Å; L131-Q166 HydrophobicContact CD1-CG 4.04Å; L131-L168 HydrophobicContact CD1-CB 4.22Å
132L98.8Very high95.4Very high0 Ų028.6 Ų28.60%014%0.14CC..EExtended strand (participates in β ladder)trans-111.1109.8175.9-173.864.7000109.8M54 L56 L111 I129 I134 I149 M150 P165 Q166 I167 L168M54-L132 HydrophobicContact CB-CD1 3.77Å; M54-L132 HydrophobicContact CG-CD1 3.74Å; M54-L132 WeakPolarHBondContact O-CA 3.45Å; L56-L132 HydrophobicContact CD1-CD1 3.87Å; L56-L132 HydrophobicContact CD1-CD2 4.44Å; L56-L132 HydrophobicContact CD1-CG 4.43Å; L56-L132 HydrophobicContact CD2-CD1 4.3Å; L56-L132 HydrophobicContact CG-CD1 3.76Å; L111-L132 HydrophobicContact CD2-CD1 4.12Å; I129-L132 HydrophobicContact CG2-CB 4.45Å; L132-I134 HydrophobicContact CD2-CD1 4.13Å; L132-I134 HydrophobicContact CD2-CG1 4.4Å; L132-I134 HydrophobicContact CG-CD1 4.36Å; L132-I134 HydrophobicContact CG-CG1 4.11Å; L132-I149 HydrophobicContact CD2-CG2 4.29Å; L132-M150 HydrophobicContact CD2-SD 4.17Å; L132-P165 HydrophobicContact CB-CB 4.14Å; L132-P165 HydrophobicContact CB-CG 4.22Å; L132-Q166 PolarHBondContact N-O 3.14Å; L132-I167 HydrophobicContact CB-CD1 3.89Å; L132-I167 HydrophobicContact CD2-CD1 4.04Å; L132-I167 HydrophobicContact CG-CD1 4.47Å; L132-L168 PolarHBondContact O-N 3.16Å
133I98.8Very high95.5Very high1 Ų130.3 Ų30.31%0.00515%0.149CC..EExtended strand (participates in β ladder)trans-95.4125.5176.4-52.6-176.8000108.3A37 A41 V53 M54 V55 L56 F71 L131 L168 L170A37-I133 HydrophobicContact CB-CD1 4.32Å; A37-I133 HydrophobicContact CB-CG2 4.09Å; A41-I133 HydrophobicContact CB-CD1 4.08Å; V53-I133 HydrophobicContact CG1-CD1 3.92Å; V53-I133 HydrophobicContact CG1-CG1 4.29Å; M54-I133 PolarHBondContact O-N 3.35Å; V55-I133 CarbonylContact C-O 3.56Å; V55-I133 WeakPolarHBondContact CA-O 2.99Å; V55-I133 HydrophobicContact CG1-CB 4.31Å; V55-I133 HydrophobicContact CG1-CG2 4.31Å; V55-I133 HydrophobicContact CG2-CB 4.29Å; V55-I133 HydrophobicContact CG2-CD1 4.25Å; L56-I133 PolarHBondContact N-O 2.9Å; F71-I133 HydrophobicContact CZ-CD1 4.39Å; L131-I133 HydrophobicContact CD1-CG1 4.46Å; L131-I133 HydrophobicContact CD2-CD1 4.11Å; L131-I133 HydrophobicContact CD2-CG1 4.17Å; L131-I133 HydrophobicContact CG-CD1 4.48Å; L131-I133 HydrophobicContact CG-CG1 4Å; I133-L168 CarbonylContact C-O 3.52Å; I133-L168 VanDerWaalsContact CA-O 3.31Å; I133-L168 WeakPolarHBondContact CA-O 3.44Å; I133-L168 HydrophobicContact CD1-CD2 4.24Å; I133-L168 HydrophobicContact CG1-CB 4.24Å; I133-L168 HydrophobicContact CG1-CD2 4.19Å; I133-L168 HydrophobicContact CG2-CD2 4.32Å; I133-L170 HydrophobicContact CG2-CD1 4Å; I133-L170 HydrophobicContact CG2-CG 4.32Å
134I98.6Very high95.5Very high0 Ų028.8 Ų28.80%015%0.146CC..EExtended strand (participates in β ladder)trans-117.8107.6-178.8-55.7178.9000108.6L56 L132 C137 Y146 M150 L168 L170 L196L56-I134 HydrophobicContact CD1-CG1 4.34Å; L132-I134 HydrophobicContact CD2-CD1 4.13Å; L132-I134 HydrophobicContact CD2-CG1 4.4Å; L132-I134 HydrophobicContact CG-CD1 4.36Å; L132-I134 HydrophobicContact CG-CG1 4.11Å; I134-C137 HydrophobicContact CB-CB 4.2Å; I134-C137 HydrophobicContact CG2-CB 3.91Å; I134-C137 WeakPolarHBondContact O-CB 3.34Å; I134-Y146 HydrophobicContact CG2-CD1 3.98Å; I134-Y146 HydrophobicContact CG2-CD2 3.7Å; I134-Y146 HydrophobicContact CG2-CE1 3.93Å; I134-Y146 HydrophobicContact CG2-CE2 3.66Å; I134-Y146 HydrophobicContact CG2-CG 3.87Å; I134-M150 HydrophobicContact CD1-CG 4.08Å; I134-M150 HydrophobicContact CD1-SD 3.76Å; I134-L168 PolarHBondContact N-O 3.42Å; I134-L170 PolarHBondContact O-N 3.26Å; I134-L196 HydrophobicContact CD1-CD2 3.63Å
135D97.3Very high95.5Very high6 Ų630.5 Ų30.53%0.03216%0.156CC..THydrogen-bonded Turntrans-78.7145176-167.636.1000111.4L56 V57 H66 C137 Y146L56-D135 WeakPolarHBondContact O-CB 3.4Å; L56-D135 PolarHBondContact O-N 2.93Å; V57-D135 HydrophobicContact CG1-CB 4.21Å; H66-D135 IonicContact CD2-OD2 3.91Å; H66-D135 IonicContact CE1-OD2 3.44Å; H66-D135 IonicContact NE2-OD2 2.63Å; H66-D135 PolarHBondContact NE2-OD2 3.41Å; D135-C137 VanDerWaalsContact C-N 3.27Å; D135-C137 PolarHBondContact O-N 3.24Å; D135-Y146 WeakPolarHBondContact O-CE2 3.33Å; D135-Y146 VanDerWaalsContact O-CZ 3.3Å; D135-Y146 PolarHBondContact O-OH 3.06Å
136E95.3Very high95.7Very high9 Ų928 Ų284%0.04214%0.144CC..THydrogen-bonded Turntrans47.950.1-171.4-57.9-63.4-178.200112.1H138 H139 L170 Q469E136-H138 PolarHBondContact O-N 3.37Å; E136-H138 IonicContact OE2-CE1 3.15Å; E136-H138 PolarHBondContact OE2-CE1 3.06Å; E136-H138 IonicContact OE2-ND1 2.79Å; E136-H138 PolarHBondContact OE2-ND1 2.91Å; E136-H139 PolarHBondContact O-CD2 3.09Å; E136-H139 VanDerWaalsContact O-CD2 3.24Å; E136-H139 PolarHBondContact O-N 3.4Å; E136-H139 VanDerWaalsContact O-N 3.13Å; E136-L170 CarbonylContact C-O 3.58Å; E136-L170 VanDerWaalsContact CA-O 3.27Å; E136-L170 WeakPolarHBondContact CA-O 3.49Å; E136-L170 PolarHBondContact N-O 3.31Å; E136-Q469 PolarHBondContact OE1-NE2 2.95Å; E136-Q469 PolarHBondContact OE2-NE2 3.49Å
137C97Very high95.7Very high0 Ų028.2 Ų28.20%015%0.145CC..G310 helixtrans-64.9-10-16975.30000114.5I134 D135 H139 T140 L170 L196I134-C137 HydrophobicContact CB-CB 4.2Å; I134-C137 HydrophobicContact CG2-CB 3.91Å; I134-C137 WeakPolarHBondContact O-CB 3.34Å; D135-C137 VanDerWaalsContact C-N 3.27Å; D135-C137 PolarHBondContact O-N 3.24Å; C137-H139 PolarHBondContact O-N 3.13Å; C137-T140 WeakPolarHBondContact O-CB 3.48Å; C137-T140 PolarHBondContact O-N 3.02Å; C137-T140 PolarHBondContact O-OG1 2.89Å; C137-L170 PolarHBondContact N-O 3.1Å; C137-L196 HydrophobicContact CB-CD1 3.7Å; C137-L196 HydrophobicContact CB-CD2 4.37Å
138H95Very high95.8Very high4 Ų429 Ų292%0.01914%0.143CC..G310 helixtrans-61.6-18.6172.161.8-98.5000112.6E136 T140 H141 T171 S173 E445E136-H138 PolarHBondContact O-N 3.37Å; E136-H138 IonicContact OE2-CE1 3.15Å; E136-H138 PolarHBondContact OE2-CE1 3.06Å; E136-H138 IonicContact OE2-ND1 2.79Å; E136-H138 PolarHBondContact OE2-ND1 2.91Å; H138-T140 PolarHBondContact O-N 2.65Å; H138-H141 PolarHBondContact O-ND1 3.49Å; H138-T171 PolarHBondContact ND1-OG1 2.71Å; H138-S173 WeakPolarHBondContact CB-O 3.5Å; H138-E445 IonicContact NE2-OE1 3Å; H138-E445 PolarHBondContact NE2-OE1 3.39Å
139H94.6Very high95.9Very high50 Ų5025.4 Ų25.423%0.23112%0.124CC..G310 helixtrans-69.2-7.3169.7-69.5-59.5000113.7N58 E136 C137 H141 S144 Y146 E445N58-H139 PolarHBondContact ND2-CD2 3.1Å; N58-H139 VanDerWaalsContact ND2-CD2 3.35Å; N58-H139 PolarHBondContact ND2-NE2 2.92Å; E136-H139 PolarHBondContact O-CD2 3.09Å; E136-H139 VanDerWaalsContact O-CD2 3.24Å; E136-H139 PolarHBondContact O-N 3.4Å; E136-H139 VanDerWaalsContact O-N 3.13Å; C137-H139 PolarHBondContact O-N 3.13Å; H139-H141 PolarHBondContact O-N 2.84Å; H139-S144 WeakPolarHBondContact O-CB 3.44Å; H139-S144 PolarHBondContact O-OG 3.31Å; H139-Y146 HydrophobicContact CB-CD2 3.72Å; H139-Y146 HydrophobicContact CB-CE2 4.01Å; H139-E445 IonicContact CD2-OE2 2.65Å; H139-E445 IonicContact CE1-OE1 3.47Å; H139-E445 IonicContact CE1-OE2 3.45Å; H139-E445 IonicContact NE2-OE1 2.98Å; H139-E445 PolarHBondContact NE2-OE1 3.38Å; H139-E445 IonicContact NE2-OE2 3.52Å; H139-E445 PolarHBondContact NE2-OE2 2.96Å
140T96.3Very high95.9Very high0 Ų025.3 Ų25.30%012%0.123CC..  trans-77.762179.8-42.60000111.7C137 H138 N147 M150 N195 L196C137-T140 WeakPolarHBondContact O-CB 3.48Å; C137-T140 PolarHBondContact O-N 3.02Å; C137-T140 PolarHBondContact O-OG1 2.89Å; H138-T140 PolarHBondContact O-N 2.65Å; T140-N147 HydrophobicContact CG2-CB 4.22Å; T140-M150 HydrophobicContact CG2-CB 4.07Å; T140-M150 HydrophobicContact CG2-CG 3.76Å; T140-N195 HydrophobicContact CG2-CB 4.05Å; T140-N195 WeakPolarHBondContact O-CB 3.4Å; T140-N195 PolarHBondContact O-ND2 3.24Å; T140-L196 HydrophobicContact CG2-CD2 3.94Å; T140-L196 HydrophobicContact CG2-CG 3.99Å
141H91Very high95.7Very high53 Ų5325.7 Ų25.725%0.24512%0.121CC..SBendtrans-147.1162177.768.6-82000110.2H138 H139 E143 S144 I192H138-H141 PolarHBondContact O-ND1 3.49Å; H139-H141 PolarHBondContact O-N 2.84Å; H141-E143 PolarHBondContact O-N 3.48Å; H141-S144 WeakPolarHBondContact O-CB 3.44Å; H141-S144 PolarHBondContact O-N 3.12Å; H141-S144 PolarHBondContact O-OG 2.65Å; H141-I192 HydrophobicContact CB-CD1 3.95Å
142K89.6Confident95.5Very high147 Ų14727.6 Ų27.664%0.63913%0.133SC*.THydrogen-bonded Turntrans52.4-137.6179.4-64.3168.9-173.4167.50112S144 N147 R151K142-S144 VanDerWaalsContact C-N 3.34Å; K142-N147 PolarHBondContact O-ND2 3.39Å; K142-R151 PolarHBondContact O-NH2 2.81Å
143E89.1Confident95.5Very high87 Ų8727.9 Ų27.941%0.40714%0.135SC..THydrogen-bonded Turntrans-95.622.6-175.8-65.2-65114.900113.2H141 K148 R151H141-E143 PolarHBondContact O-N 3.48Å; E143-K148 WeakPolarHBondContact O-CE 3.29Å; E143-R151 IonicContact OE1-CZ 3.97Å; E143-R151 IonicContact OE1-NH1 2.72Å; E143-R151 PolarHBondContact OE1-NH1 3.15Å; E143-R151 IonicContact OE1-NH2 3.54Å; E143-R151 PolarHBondContact OE1-NH2 3.24Å; E143-R151 IonicContact OE2-NH1 2.61Å
144S93.3Very high95.4Very high32 Ų3228.1 Ų28.122%0.22414%0.136CC..  trans-64.5157.917679.40000111.5H139 H141 K142 Y146 N147 K148H139-S144 WeakPolarHBondContact O-CB 3.44Å; H139-S144 PolarHBondContact O-OG 3.31Å; H141-S144 WeakPolarHBondContact O-CB 3.44Å; H141-S144 PolarHBondContact O-N 3.12Å; H141-S144 PolarHBondContact O-OG 2.65Å; K142-S144 VanDerWaalsContact C-N 3.34Å; S144-Y146 VanDerWaalsContact C-N 3.35Å; S144-Y146 PolarHBondContact O-N 2.61Å; S144-N147 PolarHBondContact O-N 3.02Å; S144-N147 WeakPolarHBondContact OG-CB 3.33Å; S144-N147 PolarHBondContact OG-N 2.82Å; S144-N147 VanDerWaalsContact OG-N 3.15Å; S144-K148 WeakPolarHBondContact O-CG 3.48Å; S144-K148 PolarHBondContact O-N 2.85Å
145V95.2Very high95.2Very high36 Ų3631.1 Ų31.122%0.21815%0.15CC..Hα-helixtrans-64.2-41.3-179.8-174.20000111.2A108 Q109 Y112 N147 K148 I149A108-V145 HydrophobicContact CB-CB 4.01Å; A108-V145 HydrophobicContact CB-CG1 3.67Å; Q109-V145 VanDerWaalsContact OE1-CG2 3.22Å; Y112-V145 HydrophobicContact CD1-CG1 4.49Å; Y112-V145 HydrophobicContact CG-CG1 4.2Å; V145-N147 VanDerWaalsContact C-N 3.32Å; V145-N147 PolarHBondContact O-N 2.94Å; V145-K148 PolarHBondContact O-N 3.49Å; V145-I149 HydrophobicContact CG1-CD1 4.25Å; V145-I149 WeakPolarHBondContact O-CG1 3.48Å; V145-I149 PolarHBondContact O-N 3.06Å; V145-I149 VanDerWaalsContact O-N 3.07Å
146Y98Very high95.1Very high6 Ų632.9 Ų32.92%0.02416%0.157CC..Hα-helixtrans-55.3-47.8172.9-67.3-22.8000111.7L56 V57 N58 A108 I134 D135 H139 S144 K148 I149 M150L56-Y146 HydrophobicContact CB-CD1 4.48Å; L56-Y146 HydrophobicContact CB-CE1 3.8Å; L56-Y146 HydrophobicContact CD1-CD1 4.38Å; L56-Y146 HydrophobicContact CD1-CE1 4.48Å; L56-Y146 PolarHBondContact O-OH 3.23Å; V57-Y146 VanDerWaalsContact CA-OH 3.23Å; V57-Y146 WeakPolarHBondContact CA-OH 3.49Å; N58-Y146 HydrophobicContact CB-CE2 4.4Å; N58-Y146 PolarHBondContact N-OH 3.42Å; A108-Y146 HydrophobicContact CB-CD1 3.49Å; A108-Y146 VanDerWaalsContact CB-CD1 3.49Å; A108-Y146 HydrophobicContact CB-CE1 3.44Å; A108-Y146 VanDerWaalsContact CB-CE1 3.44Å; I134-Y146 HydrophobicContact CG2-CD1 3.98Å; I134-Y146 HydrophobicContact CG2-CD2 3.7Å; I134-Y146 HydrophobicContact CG2-CE1 3.93Å; I134-Y146 HydrophobicContact CG2-CE2 3.66Å; I134-Y146 HydrophobicContact CG2-CG 3.87Å; D135-Y146 WeakPolarHBondContact O-CE2 3.33Å; D135-Y146 VanDerWaalsContact O-CZ 3.3Å; D135-Y146 PolarHBondContact O-OH 3.06Å; H139-Y146 HydrophobicContact CB-CD2 3.72Å; H139-Y146 HydrophobicContact CB-CE2 4.01Å; S144-Y146 VanDerWaalsContact C-N 3.35Å; S144-Y146 PolarHBondContact O-N 2.61Å; Y146-K148 VanDerWaalsContact C-N 3.28Å; Y146-K148 PolarHBondContact O-N 2.78Å; Y146-I149 PolarHBondContact O-N 3.18Å; Y146-M150 WeakPolarHBondContact O-CG 3.33Å; Y146-M150 PolarHBondContact O-N 3.47Å
147N97.1Very high95.1Very high4 Ų435 Ų352%0.02117%0.166CC..Hα-helixtrans-67.8-30.3-178.5-157.233.7000112.2T140 K142 S144 V145 M150 R151T140-N147 HydrophobicContact CG2-CB 4.22Å; K142-N147 PolarHBondContact O-ND2 3.39Å; S144-N147 PolarHBondContact O-N 3.02Å; S144-N147 WeakPolarHBondContact OG-CB 3.33Å; S144-N147 PolarHBondContact OG-N 2.82Å; S144-N147 VanDerWaalsContact OG-N 3.15Å; V145-N147 VanDerWaalsContact C-N 3.32Å; V145-N147 PolarHBondContact O-N 2.94Å; N147-M150 PolarHBondContact O-N 3.16Å; N147-R151 PolarHBondContact ND2-NE 2.9Å; N147-R151 WeakPolarHBondContact O-CB 3.43Å; N147-R151 WeakPolarHBondContact O-CD 3.28Å; N147-R151 WeakPolarHBondContact O-CG 3.32Å; N147-R151 PolarHBondContact O-N 3.32Å
148K95.8Very high95Very high61 Ų6138.5 Ų38.527%0.26519%0.185SC..Hα-helixtrans-66.1-44.7173.8-69.7172.6177.1-172.10112.2Y112 E143 S144 V145 Y146 M150 R151 C152Y112-K148 HydrophobicContact CD2-CB 3.95Å; Y112-K148 HydrophobicContact CE1-CD 3.85Å; Y112-K148 HydrophobicContact CE2-CB 3.56Å; Y112-K148 HydrophobicContact CE2-CD 4.22Å; Y112-K148 HydrophobicContact CE2-CG 4.44Å; E143-K148 WeakPolarHBondContact O-CE 3.29Å; S144-K148 WeakPolarHBondContact O-CG 3.48Å; S144-K148 PolarHBondContact O-N 2.85Å; V145-K148 PolarHBondContact O-N 3.49Å; Y146-K148 VanDerWaalsContact C-N 3.28Å; Y146-K148 PolarHBondContact O-N 2.78Å; K148-M150 VanDerWaalsContact C-N 3.34Å; K148-R151 PolarHBondContact O-N 3.04Å; K148-C152 PolarHBondContact O-N 3.07Å; K148-C152 PolarHBondContact O-SG 2.71Å
149I97.6Very high94.9Very high0 Ų045.3 Ų45.30%022%0.215CC..Hα-helixtrans-60.1-48174.2-65164000109.7L56 A108 L111 Y112 L115 L126 L132 V145 Y146 R151 C152 Y153L56-I149 HydrophobicContact CD1-CD1 3.74Å; A108-I149 HydrophobicContact CB-CD1 4.28Å; A108-I149 WeakPolarHBondContact O-CD1 3.47Å; L111-I149 HydrophobicContact CB-CD1 4.39Å; L111-I149 HydrophobicContact CD2-CD1 4.28Å; L111-I149 HydrophobicContact CD2-CG2 4.21Å; L111-I149 HydrophobicContact CG-CD1 4.45Å; Y112-I149 HydrophobicContact CD2-CG1 4.08Å; Y112-I149 HydrophobicContact CG-CG1 4.43Å; L115-I149 HydrophobicContact CD1-CB 4.5Å; L115-I149 HydrophobicContact CD1-CG1 4.18Å; L115-I149 HydrophobicContact CD1-CG2 4.12Å; L126-I149 HydrophobicContact CD2-CG2 4.39Å; L132-I149 HydrophobicContact CD2-CG2 4.29Å; V145-I149 HydrophobicContact CG1-CD1 4.25Å; V145-I149 WeakPolarHBondContact O-CG1 3.48Å; V145-I149 PolarHBondContact O-N 3.06Å; V145-I149 VanDerWaalsContact O-N 3.07Å; Y146-I149 PolarHBondContact O-N 3.18Å; I149-R151 VanDerWaalsContact C-N 3.33Å; I149-R151 PolarHBondContact O-N 3.01Å; I149-C152 WeakPolarHBondContact O-CB 3.47Å; I149-C152 PolarHBondContact O-N 2.89Å; I149-C152 VanDerWaalsContact O-N 3.13Å; I149-Y153 PolarHBondContact O-N 3.47Å
150M98.1Very high94.8Very high1 Ų145.7 Ų45.71%0.00523%0.232CC..Hα-helixtrans-68.8-28.2-179.1-70.5-47.2-60.600113.8L132 I134 T140 Y146 N147 K148 Y153 V154 I167 N195 L196L132-M150 HydrophobicContact CD2-SD 4.17Å; I134-M150 HydrophobicContact CD1-CG 4.08Å; I134-M150 HydrophobicContact CD1-SD 3.76Å; T140-M150 HydrophobicContact CG2-CB 4.07Å; T140-M150 HydrophobicContact CG2-CG 3.76Å; Y146-M150 WeakPolarHBondContact O-CG 3.33Å; Y146-M150 PolarHBondContact O-N 3.47Å; N147-M150 PolarHBondContact O-N 3.16Å; K148-M150 VanDerWaalsContact C-N 3.34Å; M150-Y153 HydrophobicContact CE-CD1 3.59Å; M150-Y153 HydrophobicContact CE-CD2 4.39Å; M150-Y153 HydrophobicContact CE-CE1 4.18Å; M150-Y153 HydrophobicContact CE-CG 3.73Å; M150-Y153 WeakPolarHBondContact O-CB 3.35Å; M150-Y153 PolarHBondContact O-N 3.4Å; M150-V154 WeakPolarHBondContact O-CG2 3.37Å; M150-V154 PolarHBondContact O-N 2.84Å; M150-I167 HydrophobicContact CE-CD1 3.82Å; M150-I167 HydrophobicContact CE-CG1 3.87Å; M150-I167 HydrophobicContact CE-CG2 4.39Å; M150-I167 HydrophobicContact SD-CD1 4.1Å; M150-N195 VanDerWaalsContact CB-O 3.23Å; M150-N195 WeakPolarHBondContact CB-O 3.24Å; M150-L196 HydrophobicContact CG-CD2 4.19Å
151R95.4Very high94.6Very high43 Ų4349.1 Ų49.116%0.16225%0.248CC..Hα-helixtrans-64.1-40.9169.7-77.6165.8-176.6-179.62111.6K142 E143 N147 K148 I149 Y153 V154 E155K142-R151 PolarHBondContact O-NH2 2.81Å; E143-R151 IonicContact OE1-CZ 3.97Å; E143-R151 IonicContact OE1-NH1 2.72Å; E143-R151 PolarHBondContact OE1-NH1 3.15Å; E143-R151 IonicContact OE1-NH2 3.54Å; E143-R151 PolarHBondContact OE1-NH2 3.24Å; E143-R151 IonicContact OE2-NH1 2.61Å; N147-R151 PolarHBondContact ND2-NE 2.9Å; N147-R151 WeakPolarHBondContact O-CB 3.43Å; N147-R151 WeakPolarHBondContact O-CD 3.28Å; N147-R151 WeakPolarHBondContact O-CG 3.32Å; N147-R151 PolarHBondContact O-N 3.32Å; K148-R151 PolarHBondContact O-N 3.04Å; I149-R151 VanDerWaalsContact C-N 3.33Å; I149-R151 PolarHBondContact O-N 3.01Å; R151-Y153 VanDerWaalsContact C-N 3.29Å; R151-Y153 PolarHBondContact O-N 2.79Å; R151-V154 PolarHBondContact O-N 2.79Å; R151-E155 WeakPolarHBondContact O-CB 3.32Å; R151-E155 PolarHBondContact O-N 3.11Å
152C94.8Very high94.3Very high39 Ų3958.2 Ų58.226%0.26428%0.28SS..Hα-helixtrans-61-41.4172.6-62.50000111L126 K148 I149 K156L126-C152 HydrophobicContact CD1-CB 4.16Å; K148-C152 PolarHBondContact O-N 3.07Å; K148-C152 PolarHBondContact O-SG 2.71Å; I149-C152 WeakPolarHBondContact O-CB 3.47Å; I149-C152 PolarHBondContact O-N 2.89Å; I149-C152 VanDerWaalsContact O-N 3.13Å; C152-K156 WeakPolarHBondContact O-CG 3.4Å; C152-K156 PolarHBondContact O-N 3.46Å; C152-K156 VanDerWaalsContact O-N 3.1Å
153Y97.3Very high94.3Very high6 Ų660.9 Ų60.92%0.02429%0.286CS..Hα-helixtrans-59.9-53.2174173.4-81.2000112N22 I149 M150 R151 E155 K156 K157 I164 P165 I167 D197N22-Y153 PolarHBondContact ND2-OH 3.27Å; N22-Y153 VanDerWaalsContact ND2-OH 3.09Å; I149-Y153 PolarHBondContact O-N 3.47Å; M150-Y153 HydrophobicContact CE-CD1 3.59Å; M150-Y153 HydrophobicContact CE-CD2 4.39Å; M150-Y153 HydrophobicContact CE-CE1 4.18Å; M150-Y153 HydrophobicContact CE-CG 3.73Å; M150-Y153 WeakPolarHBondContact O-CB 3.35Å; M150-Y153 PolarHBondContact O-N 3.4Å; R151-Y153 VanDerWaalsContact C-N 3.29Å; R151-Y153 PolarHBondContact O-N 2.79Å; Y153-E155 VanDerWaalsContact C-N 3.3Å; Y153-E155 PolarHBondContact O-N 3.35Å; Y153-K156 PolarHBondContact O-N 2.96Å; Y153-K157 PolarHBondContact O-N 2.8Å; Y153-I164 HydrophobicContact CD2-CB 4.17Å; Y153-I164 HydrophobicContact CE1-CD1 4.29Å; Y153-I164 HydrophobicContact CE2-CB 3.74Å; Y153-I164 HydrophobicContact CE2-CD1 3.8Å; Y153-I164 HydrophobicContact CE2-CG1 3.88Å; Y153-P165 HydrophobicContact CD2-CG 4.13Å; Y153-P165 HydrophobicContact CE2-CG 4.19Å; Y153-P165 VanDerWaalsContact CE2-O 3.3Å; Y153-P165 WeakPolarHBondContact CE2-O 3.47Å; Y153-I167 HydrophobicContact CD2-CD1 4.02Å; Y153-I167 HydrophobicContact CE1-CG1 4.49Å; Y153-I167 HydrophobicContact CE2-CD1 3.82Å; Y153-I167 HydrophobicContact CE2-CG1 4.01Å; Y153-D197 HydrophobicContact CD1-CB 4.37Å; Y153-D197 HydrophobicContact CE1-CB 3.61Å; Y153-D197 WeakPolarHBondContact CE1-OD2 3.39Å; Y153-D197 PolarHBondContact OH-OD2 3.19Å; Y153-D197 VanDerWaalsContact OH-OD2 3.12Å
154V96.8Very high94.5Very high6 Ų658.7 Ų58.74%0.03628%0.277CS..Hα-helixtrans-62.3-38.8-178.7169.70000110.9M150 R151 K157 L158 Q528 I532M150-V154 WeakPolarHBondContact O-CG2 3.37Å; M150-V154 PolarHBondContact O-N 2.84Å; R151-V154 PolarHBondContact O-N 2.79Å; V154-K157 WeakPolarHBondContact O-CB 3.32Å; V154-K157 PolarHBondContact O-N 3.43Å; V154-L158 HydrophobicContact CG1-CD1 3.97Å; V154-L158 HydrophobicContact CG1-CG 4.24Å; V154-L158 WeakPolarHBondContact O-CB 3.5Å; V154-L158 WeakPolarHBondContact O-CG 3.39Å; V154-L158 PolarHBondContact O-N 3.47Å; V154-Q528 HydrophobicContact CG1-CB 3.69Å; V154-Q528 HydrophobicContact CG1-CG 3.79Å; V154-Q528 HydrophobicContact CG2-CG 4.2Å; V154-I532 HydrophobicContact CG1-CD1 4.28Å; V154-I532 HydrophobicContact CG1-CG1 4.06Å
155E94.8Very high94.7Very high64 Ų6457.2 Ų57.230%0.29927%0.266SS..Hα-helixtrans-62.3-44.9175.9-170.1179.4172.500111.9R151 Y153 L158 K159 I532R151-E155 WeakPolarHBondContact O-CB 3.32Å; R151-E155 PolarHBondContact O-N 3.11Å; Y153-E155 VanDerWaalsContact C-N 3.3Å; Y153-E155 PolarHBondContact O-N 3.35Å; E155-L158 PolarHBondContact O-N 3.44Å; E155-K159 HydrophobicContact CG-CD 4.25Å; E155-K159 WeakPolarHBondContact O-CB 3.36Å; E155-K159 VanDerWaalsContact O-CG 3.32Å; E155-K159 WeakPolarHBondContact O-CG 3.43Å; E155-K159 PolarHBondContact O-N 3.12Å; E155-K159 WeakPolarHBondContact OE1-CE 3.38Å; E155-K159 IonicContact OE1-NZ 2.97Å; E155-K159 PolarHBondContact OE1-NZ 3.38Å; E155-I532 HydrophobicContact CB-CD1 4.08Å
156K95.2Very high94.9Very high42 Ų4256.4 Ų56.418%0.18326%0.26CS..Hα-helixtrans-64-41.3175.4-71.6-179.7-172.3-1010111.6E125 L126 C152 Y153 K159 G160 Q161 I164E125-K156 IonicContact OE1-NZ 3.87Å; E125-K156 IonicContact OE2-NZ 2.75Å; E125-K156 PolarHBondContact OE2-NZ 2.97Å; L126-K156 HydrophobicContact CB-CD 4.42Å; L126-K156 HydrophobicContact CD1-CD 4.17Å; C152-K156 WeakPolarHBondContact O-CG 3.4Å; C152-K156 PolarHBondContact O-N 3.46Å; C152-K156 VanDerWaalsContact O-N 3.1Å; Y153-K156 PolarHBondContact O-N 2.96Å; K156-K159 PolarHBondContact O-N 3.29Å; K156-G160 PolarHBondContact O-N 3.21Å; K156-Q161 HydrophobicContact CB-CB 4.13Å; K156-Q161 VanDerWaalsContact O-CB 3.27Å; K156-Q161 WeakPolarHBondContact O-CB 3.12Å; K156-Q161 PolarHBondContact O-N 3.42Å; K156-I164 HydrophobicContact CB-CG2 4.27Å
157K95.4Very high94.9Very high53 Ų5356.1 Ų56.123%0.2326%0.259CS..Hα-helixtrans-57.4-51.9174.2179.8-163.9171.6-167.10111.5Y153 V154 K159 G160 I164 D197Y153-K157 PolarHBondContact O-N 2.8Å; V154-K157 WeakPolarHBondContact O-CB 3.32Å; V154-K157 PolarHBondContact O-N 3.43Å; K157-K159 PolarHBondContact O-N 3.43Å; K157-G160 PolarHBondContact O-N 2.98Å; K157-I164 HydrophobicContact CB-CD1 3.93Å; K157-I164 HydrophobicContact CG-CD1 4.24Å; K157-D197 WeakPolarHBondContact CD-OD2 3.47Å; K157-D197 IonicContact NZ-OD1 3.28Å; K157-D197 PolarHBondContact NZ-OD1 3.15Å; K157-D197 IonicContact NZ-OD2 2.7Å
158L94.4Very high95Very high74 Ų7456 Ų5639%0.38726%0.258SS..Hα-helixtrans-66.9-25.3-178.7-68.2178000112.8V154 E155 G160 I532V154-L158 HydrophobicContact CG1-CD1 3.97Å; V154-L158 HydrophobicContact CG1-CG 4.24Å; V154-L158 WeakPolarHBondContact O-CB 3.5Å; V154-L158 WeakPolarHBondContact O-CG 3.39Å; V154-L158 PolarHBondContact O-N 3.47Å; E155-L158 PolarHBondContact O-N 3.44Å; L158-G160 PolarHBondContact O-N 2.91Å; L158-I532 HydrophobicContact CD1-CG1 4.03Å
159K94Very high95.1Very high148 Ų14853 Ų5364%0.64325%0.245SC*.THydrogen-bonded Turntrans-76.9-1.6170.3-73.9170.5172.2170.70113.7E155 K156 K157E155-K159 HydrophobicContact CG-CD 4.25Å; E155-K159 WeakPolarHBondContact O-CB 3.36Å; E155-K159 VanDerWaalsContact O-CG 3.32Å; E155-K159 WeakPolarHBondContact O-CG 3.43Å; E155-K159 PolarHBondContact O-N 3.12Å; E155-K159 WeakPolarHBondContact OE1-CE 3.38Å; E155-K159 IonicContact OE1-NZ 2.97Å; E155-K159 PolarHBondContact OE1-NZ 3.38Å; K156-K159 PolarHBondContact O-N 3.29Å; K157-K159 PolarHBondContact O-N 3.43Å
160G92.6Very high95.2Very high57 Ų5753.2 Ų53.259%0.58825%0.246SC*.THydrogen-bonded Turntrans79.418.8178.600000114.6K156 K157 L158 R162K156-G160 PolarHBondContact O-N 3.21Å; K157-G160 PolarHBondContact O-N 2.98Å; L158-G160 PolarHBondContact O-N 2.91Å; G160-R162 PolarHBondContact O-N 3.01Å
161Q92.1Very high95Very high72 Ų7253.1 Ų53.134%0.33625%0.246SC..  trans-67.2125177-169.8164.8-10.800110.3K156 I164K156-Q161 HydrophobicContact CB-CB 4.13Å; K156-Q161 VanDerWaalsContact O-CB 3.27Å; K156-Q161 WeakPolarHBondContact O-CB 3.12Å; K156-Q161 PolarHBondContact O-N 3.42Å; Q161-I164 HydrophobicContact CG-CG2 4.48Å
162R84Confident94.9Very high244 Ų24451.1 Ų51.192%0.92124%0.238SC*.SBendtrans-82.8-32-172.8-66.4-173.8177.8-176.4-0.6114.5G160 I164G160-R162 PolarHBondContact O-N 3.01Å; R162-I164 PolarHBondContact O-N 3.15Å
163R88.9Confident94.8Very high203 Ų20349.3 Ų49.377%0.76623%0.226SC*.  trans-95.289.1-178.9-68.2-172.7179.3-175.6-0.2109.8S127S127-R163 WeakPolarHBondContact CB-O 3.44Å
164I94.3Very high94.5Very high41 Ų4149.1 Ų49.121%0.2123%0.226CC..  trans-133.6149.5173.460.3-178.5000108.8Y153 K156 K157 Q161 R162Y153-I164 HydrophobicContact CD2-CB 4.17Å; Y153-I164 HydrophobicContact CE1-CD1 4.29Å; Y153-I164 HydrophobicContact CE2-CB 3.74Å; Y153-I164 HydrophobicContact CE2-CD1 3.8Å; Y153-I164 HydrophobicContact CE2-CG1 3.88Å; K156-I164 HydrophobicContact CB-CG2 4.27Å; K157-I164 HydrophobicContact CB-CD1 3.93Å; K157-I164 HydrophobicContact CG-CD1 4.24Å; Q161-I164 HydrophobicContact CG-CG2 4.48Å; R162-I164 PolarHBondContact O-N 3.15Å
165P97.6Very high94.4Very high1 Ų148.8 Ų48.81%0.00622%0.224CC..  trans-69.9149.3-172.924.8-32.6000112.2L126 I129 T130 L132 Y153 I167L126-P165 WeakPolarHBondContact O-CD 3.33Å; I129-P165 HydrophobicContact CB-CB 4.22Å; I129-P165 HydrophobicContact CB-CG 4.48Å; I129-P165 HydrophobicContact CG2-CB 3.96Å; I129-P165 WeakPolarHBondContact O-CB 3.48Å; T130-P165 WeakPolarHBondContact O-CA 3.42Å; L132-P165 HydrophobicContact CB-CB 4.14Å; L132-P165 HydrophobicContact CB-CG 4.22Å; Y153-P165 HydrophobicContact CD2-CG 4.13Å; Y153-P165 HydrophobicContact CE2-CG 4.19Å; Y153-P165 VanDerWaalsContact CE2-O 3.3Å; Y153-P165 WeakPolarHBondContact CE2-O 3.47Å; P165-I167 HydrophobicContact CG-CD1 4.27Å
166Q98.5Very high94.3Very high20 Ų2045.8 Ų45.89%0.09321%0.21CC..EExtended strand (participates in β ladder)trans-61.3142.4160.4-175.4-176.26.200109.5A17 G20 E21 N22 T130 L131 L132A17-Q166 PolarHBondContact O-NE2 2.97Å; G20-Q166 VanDerWaalsContact C-NE2 3.33Å; E21-Q166 PolarHBondContact O-NE2 3.25Å; N22-Q166 WeakPolarHBondContact OD1-CA 3.31Å; T130-Q166 PolarHBondContact O-N 3.41Å; L131-Q166 CarbonylContact C-O 3.52Å; L131-Q166 WeakPolarHBondContact CA-O 3.49Å; L131-Q166 HydrophobicContact CD1-CB 3.94Å; L131-Q166 HydrophobicContact CD1-CG 4.04Å; L132-Q166 PolarHBondContact N-O 3.14Å
167I98.8Very high94Very high0 Ų046.5 Ų46.50%023%0.229CC..EExtended strand (participates in β ladder)trans-107.2129.8179.6-51.9-57.8000110.9N22 V23 L132 M150 Y153 P165 L196N22-I167 WeakPolarHBondContact CA-O 3.38Å; N22-I167 HydrophobicContact CB-CB 4.23Å; N22-I167 PolarHBondContact OD1-N 3.49Å; V23-I167 PolarHBondContact N-O 3.11Å; L132-I167 HydrophobicContact CB-CD1 3.89Å; L132-I167 HydrophobicContact CD2-CD1 4.04Å; L132-I167 HydrophobicContact CG-CD1 4.47Å; M150-I167 HydrophobicContact CE-CD1 3.82Å; M150-I167 HydrophobicContact CE-CG1 3.87Å; M150-I167 HydrophobicContact CE-CG2 4.39Å; M150-I167 HydrophobicContact SD-CD1 4.1Å; Y153-I167 HydrophobicContact CD2-CD1 4.02Å; Y153-I167 HydrophobicContact CE1-CG1 4.49Å; Y153-I167 HydrophobicContact CE2-CD1 3.82Å; Y153-I167 HydrophobicContact CE2-CG1 4.01Å; P165-I167 HydrophobicContact CG-CD1 4.27Å; I167-L196 HydrophobicContact CG2-CD2 4.22Å; I167-L196 WeakPolarHBondContact CG2-O 3.2Å
168L98.8Very high93.8Very high0 Ų046.3 Ų46.30%024%0.242CC..EExtended strand (participates in β ladder)trans-125101.8170.7-178.165.4000110.4A17 V23 I25 A37 V40 L131 L132 I133 I134 L170A17-L168 HydrophobicContact CB-CD1 4.1Å; V23-L168 HydrophobicContact CB-CD1 4.41Å; V23-L168 CarbonylContact O-C 3.27Å; V23-L168 WeakPolarHBondContact O-CA 3.35Å; I25-L168 HydrophobicContact CD1-CD1 3.79Å; I25-L168 HydrophobicContact CG1-CD1 3.95Å; A37-L168 HydrophobicContact CB-CD2 4.01Å; V40-L168 HydrophobicContact CB-CD2 3.97Å; V40-L168 HydrophobicContact CG1-CD2 4.01Å; V40-L168 HydrophobicContact CG2-CD2 4.22Å; L131-L168 HydrophobicContact CD1-CB 4.22Å; L132-L168 PolarHBondContact O-N 3.16Å; I133-L168 CarbonylContact C-O 3.52Å; I133-L168 VanDerWaalsContact CA-O 3.31Å; I133-L168 WeakPolarHBondContact CA-O 3.44Å; I133-L168 HydrophobicContact CD1-CD2 4.24Å; I133-L168 HydrophobicContact CG1-CB 4.24Å; I133-L168 HydrophobicContact CG1-CD2 4.19Å; I133-L168 HydrophobicContact CG2-CD2 4.32Å; I134-L168 PolarHBondContact N-O 3.42Å; L168-L170 HydrophobicContact CD2-CD2 4.38Å; L168-L170 HydrophobicContact CG-CD2 4.15Å
169G98.6Very high93.7Very high0 Ų043.3 Ų43.30%023%0.228CC..EExtended strand (participates in β ladder)trans-86.7139.4173.300000112.2V23 I24 I25V23-G169 PolarHBondContact O-N 2.98Å; I24-G169 CarbonylContact C-O 3.6Å; I24-G169 WeakPolarHBondContact CA-O 3.49Å; I25-G169 PolarHBondContact N-O 3.15Å
170L98.1Very high93.7Very high3 Ų342.7 Ų42.72%0.01623%0.225CC..EExtended strand (participates in β ladder)trans-118.9126.4174.7-49.2175.6000109.6I25 K33 A37 I133 I134 E136 C137 L168I25-L170 HydrophobicContact CB-CD2 4.13Å; I25-L170 HydrophobicContact CD1-CD2 4.21Å; K33-L170 HydrophobicContact CB-CB 4.39Å; K33-L170 HydrophobicContact CD-CB 4.4Å; A37-L170 HydrophobicContact CB-CD1 3.68Å; A37-L170 HydrophobicContact CB-CD2 4.06Å; A37-L170 HydrophobicContact CB-CG 4.44Å; I133-L170 HydrophobicContact CG2-CD1 4Å; I133-L170 HydrophobicContact CG2-CG 4.32Å; I134-L170 PolarHBondContact O-N 3.26Å; E136-L170 CarbonylContact C-O 3.58Å; E136-L170 VanDerWaalsContact CA-O 3.27Å; E136-L170 WeakPolarHBondContact CA-O 3.49Å; E136-L170 PolarHBondContact N-O 3.31Å; C137-L170 PolarHBondContact N-O 3.1Å; L168-L170 HydrophobicContact CD2-CD2 4.38Å; L168-L170 HydrophobicContact CG-CD2 4.15Å
171T95.6Very high93.9Very high0 Ų043.5 Ų43.50%022%0.219CC..EExtended strand (participates in β ladder)trans-152.1147.7174-172.10000113I24 I25 W26 L27 K33 H138 S173I24-T171 HydrophobicContact CG2-CG2 3.86Å; I25-T171 PolarHBondContact O-N 3.03Å; I25-T171 VanDerWaalsContact O-N 3.1Å; W26-T171 WeakPolarHBondContact CA-O 3.36Å; L27-T171 PolarHBondContact N-O 3.32Å; K33-T171 WeakPolarHBondContact CD-O 3.38Å; H138-T171 PolarHBondContact ND1-OG1 2.71Å; T171-S173 VanDerWaalsContact OG1-C 3.3Å; T171-S173 PolarHBondContact OG1-N 2.95Å; T171-S173 PolarHBondContact OG1-O 3.38Å
172A92.5Very high94.2Very high0 Ų043.1 Ų43.10%022%0.219CC..SBendtrans-81.6-23.9165.500000113.1W26 L27 T29 Q468W26-A172 VanDerWaalsContact CD1-O 3.27Å; W26-A172 PolarHBondContact NE1-O 2.89Å; L27-A172 VanDerWaalsContact O-CA 3.25Å; L27-A172 WeakPolarHBondContact O-CA 3.23Å; T29-A172 WeakPolarHBondContact OG1-CB 3.25Å; A172-Q468 PolarHBondContact O-NE2 2.83Å
173S91.8Very high94.8Very high1 Ų137.1 Ų37.11%0.00720%0.201CC..  trans-160118.6-175.1-160.10000110.5H138 T171 Q468H138-S173 WeakPolarHBondContact CB-O 3.5Å; T171-S173 VanDerWaalsContact OG1-C 3.3Å; T171-S173 PolarHBondContact OG1-N 2.95Å; T171-S173 PolarHBondContact OG1-O 3.38Å; S173-Q468 PolarHBondContact OG-OE1 2.94Å
174P92.5Very high95.2Very high2 Ų232.7 Ų32.71%0.01319%0.189CC..  trans-73.8-15.9167.729.8-32.5000112.6H188 V189 I200 T505 I509P174-H188 PolarHBondContact O-NE2 3.35Å; P174-V189 HydrophobicContact CG-CG2 4.36Å; P174-I200 HydrophobicContact CG-CD1 4.13Å; P174-T505 HydrophobicContact CG-CG2 3.9Å; P174-I509 HydrophobicContact CG-CD1 3.58Å; P174-I509 HydrophobicContact CG-CG1 4.09Å
175G93.4Very high95.4Very high0 Ų030.8 Ų30.80%018%0.179CC..  trans68.2-170.5-176.300000114H188 E464G175-H188 PolarHBondContact O-CD2 2.81Å; G175-E464 WeakPolarHBondContact CA-OE1 3.39Å
176T93.5Very high95.4Very high1 Ų130.9 Ų30.91%0.00618%0.18CC..  trans-111.9-0.3178.172.60000113.7G178 A179 A185 H188 E464 L501 L504 T505T176-G178 PolarHBondContact O-N 3.37Å; T176-G178 PolarHBondContact OG1-N 3.17Å; T176-A179 WeakPolarHBondContact CB-O 3.44Å; T176-A179 WeakPolarHBondContact O-CB 3.24Å; T176-A179 PolarHBondContact O-N 3.31Å; T176-A179 PolarHBondContact OG1-N 3.41Å; T176-A179 PolarHBondContact OG1-O 3.44Å; T176-A185 HydrophobicContact CG2-CB 4.08Å; T176-H188 VanDerWaalsContact C-CD2 3.41Å; T176-E464 PolarHBondContact N-OE1 3.21Å; T176-L501 HydrophobicContact CG2-CB 4.28Å; T176-L501 HydrophobicContact CG2-CD2 4.27Å; T176-L501 WeakPolarHBondContact CG2-O 3.42Å; T176-L504 HydrophobicContact CG2-CB 4.34Å; T176-L504 HydrophobicContact CG2-CD2 4.31Å; T176-L504 HydrophobicContact CG2-CG 4.46Å; T176-T505 VanDerWaalsContact CG2-OG1 3.23Å; T176-T505 WeakPolarHBondContact CG2-OG1 3.39Å
177G89.6Confident95.3Very high57 Ų5734.2 Ų34.259%0.58820%0.199SC*.THydrogen-bonded Turntrans68.111.7-173.700000113.7H188G177-H188 VanDerWaalsContact CA-CE1 3.47Å; G177-H188 WeakPolarHBondContact CA-CE1 3.49Å; G177-H188 VanDerWaalsContact CA-ND1 3.32Å; G177-H188 WeakPolarHBondContact CA-ND1 3.45Å; G177-H188 PolarHBondContact N-CD2 3.31Å; G177-H188 PolarHBondContact N-CE1 3.03Å; G177-H188 PolarHBondContact N-ND1 3.44Å; G177-H188 PolarHBondContact N-NE2 2.82Å
178G89.8Confident95.3Very high49 Ų4935.5 Ų35.551%0.50520%0.204SC..THydrogen-bonded Turntrans91.7-1.6-172.300000114.1T176T176-G178 PolarHBondContact O-N 3.37Å; T176-G178 PolarHBondContact OG1-N 3.17Å
179A93.7Very high95.2Very high11 Ų1135.5 Ų35.59%0.09121%0.205CC..  trans-61.2138.3173.200000110.9T176 E184 A185 L501T176-A179 WeakPolarHBondContact CB-O 3.44Å; T176-A179 WeakPolarHBondContact O-CB 3.24Å; T176-A179 PolarHBondContact O-N 3.31Å; T176-A179 PolarHBondContact OG1-N 3.41Å; T176-A179 PolarHBondContact OG1-O 3.44Å; A179-E184 HydrophobicContact CB-CB 3.47Å; A179-E184 VanDerWaalsContact CB-CB 3.47Å; A179-A185 HydrophobicContact CB-CB 4.35Å; A179-L501 WeakPolarHBondContact O-CD2 3.42Å
180K94.2Very high95.2Very high135 Ų13535.7 Ų35.759%0.58721%0.205SC*.  trans-109-0.2179.1-61.4-178.9-176175.60113.1Y500K180-Y500 WeakPolarHBondContact O-CE1 3.34Å; K180-Y500 PolarHBondContact O-OH 2.98Å; K180-Y500 VanDerWaalsContact O-OH 3.09Å
181V96.8Very high95.2Very high74 Ų7439.2 Ų39.245%0.44822%0.222SC..SBendtrans-126.6151.4-179.4-60.20000109.9E183 E184 A185V181-E183 PolarHBondContact O-N 3.03Å; V181-E184 HydrophobicContact CG2-CB 3.75Å; V181-E184 VanDerWaalsContact CG2-CD 3.46Å; V181-E184 HydrophobicContact CG2-CG 3.55Å; V181-E184 PolarHBondContact O-N 3.49Å; V181-A185 PolarHBondContact O-N 3.07Å
182L97.3Very high95.3Very high64 Ų6439.4 Ų39.434%0.33522%0.223SC..Hα-helixtrans-61.6-45.7-170.1179.460.7000112.9E184 A185 V186 L504 K507 A508L182-E184 VanDerWaalsContact C-N 3.35Å; L182-E184 PolarHBondContact O-N 3.17Å; L182-A185 PolarHBondContact O-N 2.79Å; L182-A185 VanDerWaalsContact O-N 3.16Å; L182-V186 HydrophobicContact CD1-CG2 4.15Å; L182-V186 HydrophobicContact CG-CG2 4.34Å; L182-V186 VanDerWaalsContact O-CG2 3.3Å; L182-V186 WeakPolarHBondContact O-CG2 3.45Å; L182-V186 PolarHBondContact O-N 2.82Å; L182-L504 HydrophobicContact CB-CD1 3.95Å; L182-L504 HydrophobicContact CD1-CD1 4.05Å; L182-K507 HydrophobicContact CD1-CB 3.7Å; L182-A508 HydrophobicContact CD1-CB 4.25Å
183E97.1Very high95.6Very high117 Ų11739.4 Ų39.455%0.54722%0.223SC..Hα-helixtrans-61.4-42.1-178.2-67.9-59.4140.900112.2V181 V186 N187V181-E183 PolarHBondContact O-N 3.03Å; E183-V186 PolarHBondContact O-N 2.78Å; E183-N187 VanDerWaalsContact O-CG 3.25Å; E183-N187 PolarHBondContact O-N 3.37Å; E183-N187 PolarHBondContact O-ND2 3.33Å
184E97.1Very high95.9Very high110 Ų11039.4 Ų39.451%0.51422%0.223SC..Hα-helixtrans-67.6-37.8175.2-70.3177.7-174.900111.9A179 V181 L182 N187 H188A179-E184 HydrophobicContact CB-CB 3.47Å; A179-E184 VanDerWaalsContact CB-CB 3.47Å; V181-E184 HydrophobicContact CG2-CB 3.75Å; V181-E184 VanDerWaalsContact CG2-CD 3.46Å; V181-E184 HydrophobicContact CG2-CG 3.55Å; V181-E184 PolarHBondContact O-N 3.49Å; L182-E184 VanDerWaalsContact C-N 3.35Å; L182-E184 PolarHBondContact O-N 3.17Å; E184-N187 PolarHBondContact O-N 3.4Å; E184-H188 PolarHBondContact O-N 3.13Å
185A97.4Very high96.2Very high1 Ų140 Ų401%0.00823%0.226CC..Hα-helixtrans-65.7-38.1174.500000111.9T176 A179 V181 L182 H188 V189 L504 A508T176-A185 HydrophobicContact CG2-CB 4.08Å; A179-A185 HydrophobicContact CB-CB 4.35Å; V181-A185 PolarHBondContact O-N 3.07Å; L182-A185 PolarHBondContact O-N 2.79Å; L182-A185 VanDerWaalsContact O-N 3.16Å; A185-H188 PolarHBondContact O-N 3.28Å; A185-V189 WeakPolarHBondContact O-CG2 3.31Å; A185-V189 PolarHBondContact O-N 3.23Å; A185-L504 HydrophobicContact CB-CD2 4Å; A185-L504 HydrophobicContact CB-CG 3.92Å; A185-A508 HydrophobicContact CB-CB 3.91Å
186V98.3Very high96.4Very high3 Ų340 Ų402%0.01823%0.226CC..Hα-helixtrans-61.5-44.9172.3169.10000110.5L182 E183 H188 V189 L190 A508 R511 V512 M515L182-V186 HydrophobicContact CD1-CG2 4.15Å; L182-V186 HydrophobicContact CG-CG2 4.34Å; L182-V186 VanDerWaalsContact O-CG2 3.3Å; L182-V186 WeakPolarHBondContact O-CG2 3.45Å; L182-V186 PolarHBondContact O-N 2.82Å; E183-V186 PolarHBondContact O-N 2.78Å; V186-H188 VanDerWaalsContact C-N 3.32Å; V186-H188 PolarHBondContact O-N 3.18Å; V186-V189 PolarHBondContact O-N 3.15Å; V186-L190 HydrophobicContact CG1-CD1 4.06Å; V186-L190 HydrophobicContact CG1-CG 4.48Å; V186-L190 WeakPolarHBondContact O-CB 3.32Å; V186-L190 WeakPolarHBondContact O-CG 3.38Å; V186-L190 PolarHBondContact O-N 3.2Å; V186-A508 HydrophobicContact CG2-CB 3.91Å; V186-R511 HydrophobicContact CG1-CG 4.43Å; V186-R511 HydrophobicContact CG2-CB 3.84Å; V186-R511 HydrophobicContact CG2-CG 3.87Å; V186-V512 HydrophobicContact CG1-CG2 4.02Å; V186-M515 HydrophobicContact CG1-CE 3.74Å
187N97.6Very high96.6Very high91 Ų9141.1 Ų41.149%0.48723%0.232SC..Hα-helixtrans-61.1-40.5176.2-69-25.5000112E183 E184 L190 E191E183-N187 VanDerWaalsContact O-CG 3.25Å; E183-N187 PolarHBondContact O-N 3.37Å; E183-N187 PolarHBondContact O-ND2 3.33Å; E184-N187 PolarHBondContact O-N 3.4Å; N187-L190 PolarHBondContact O-N 2.73Å; N187-E191 PolarHBondContact O-N 3.01Å
188H97.1Very high97Very high26 Ų2638.6 Ų38.612%0.1221%0.205CC..Hα-helixtrans-63.7-44.5174.7175.379.8000112.3P174 G175 T176 G177 E184 A185 V186 L190 E191 I192P174-H188 PolarHBondContact O-NE2 3.35Å; G175-H188 PolarHBondContact O-CD2 2.81Å; T176-H188 VanDerWaalsContact C-CD2 3.41Å; G177-H188 VanDerWaalsContact CA-CE1 3.47Å; G177-H188 WeakPolarHBondContact CA-CE1 3.49Å; G177-H188 VanDerWaalsContact CA-ND1 3.32Å; G177-H188 WeakPolarHBondContact CA-ND1 3.45Å; G177-H188 PolarHBondContact N-CD2 3.31Å; G177-H188 PolarHBondContact N-CE1 3.03Å; G177-H188 PolarHBondContact N-ND1 3.44Å; G177-H188 PolarHBondContact N-NE2 2.82Å; E184-H188 PolarHBondContact O-N 3.13Å; A185-H188 PolarHBondContact O-N 3.28Å; V186-H188 VanDerWaalsContact C-N 3.32Å; V186-H188 PolarHBondContact O-N 3.18Å; H188-L190 VanDerWaalsContact C-N 3.31Å; H188-L190 PolarHBondContact O-N 3.18Å; H188-E191 WeakPolarHBondContact O-CB 3.32Å; H188-E191 PolarHBondContact O-N 3.45Å; H188-E191 VanDerWaalsContact O-N 3.16Å; H188-I192 PolarHBondContact O-N 3.05Å
189V97.9Very high97.4Very high1 Ų137.4 Ų37.41%0.00619%0.188CC..Hα-helixtrans-61.8-41.5175.41750000110.8P174 A185 V186 E191 I192 C193 I200 A508 I509 V512P174-V189 HydrophobicContact CG-CG2 4.36Å; A185-V189 WeakPolarHBondContact O-CG2 3.31Å; A185-V189 PolarHBondContact O-N 3.23Å; V186-V189 PolarHBondContact O-N 3.15Å; V189-E191 VanDerWaalsContact C-N 3.33Å; V189-E191 PolarHBondContact O-N 2.76Å; V189-I192 PolarHBondContact O-N 2.75Å; V189-C193 PolarHBondContact O-N 3.4Å; V189-C193 PolarHBondContact O-SG 3.28Å; V189-I200 HydrophobicContact CG1-CG2 4.5Å; V189-A508 HydrophobicContact CG2-CB 3.97Å; V189-I509 HydrophobicContact CG1-CG1 4.23Å; V189-I509 HydrophobicContact CG2-CG1 4.17Å; V189-V512 HydrophobicContact CB-CG2 4.15Å; V189-V512 HydrophobicContact CG1-CB 4.25Å; V189-V512 HydrophobicContact CG1-CG1 4.4Å; V189-V512 HydrophobicContact CG1-CG2 3.84Å
190L98.4Very high97.6Very high3 Ų337.3 Ų37.32%0.01619%0.186CC..Hα-helixtrans-62.4-38173.9-73.7170.5000112.4V186 N187 H188 C193 A194 V512 M515 F520 K523 I527V186-L190 HydrophobicContact CG1-CD1 4.06Å; V186-L190 HydrophobicContact CG1-CG 4.48Å; V186-L190 WeakPolarHBondContact O-CB 3.32Å; V186-L190 WeakPolarHBondContact O-CG 3.38Å; V186-L190 PolarHBondContact O-N 3.2Å; N187-L190 PolarHBondContact O-N 2.73Å; H188-L190 VanDerWaalsContact C-N 3.31Å; H188-L190 PolarHBondContact O-N 3.18Å; L190-C193 PolarHBondContact O-N 2.95Å; L190-A194 VanDerWaalsContact O-CB 3.27Å; L190-A194 WeakPolarHBondContact O-CB 3.33Å; L190-A194 PolarHBondContact O-N 2.74Å; L190-V512 HydrophobicContact CD2-CG1 4.12Å; L190-V512 HydrophobicContact CD2-CG2 4.1Å; L190-V512 HydrophobicContact CG-CG2 4.01Å; L190-M515 HydrophobicContact CD1-CE 4.2Å; L190-M515 HydrophobicContact CD2-SD 4.1Å; L190-F520 HydrophobicContact CD2-CD2 4.02Å; L190-F520 HydrophobicContact CD2-CE2 4.05Å; L190-K523 HydrophobicContact CD1-CD 3.88Å; L190-I527 HydrophobicContact CB-CD1 3.92Å
191E97.8Very high97.7Very high78 Ų7831.7 Ų31.736%0.36416%0.163SC..Hα-helixtrans-62-45.5174.9-169.5-170.9159.600111.1N187 H188 V189 A194 N195N187-E191 PolarHBondContact O-N 3.01Å; H188-E191 WeakPolarHBondContact O-CB 3.32Å; H188-E191 PolarHBondContact O-N 3.45Å; H188-E191 VanDerWaalsContact O-N 3.16Å; V189-E191 VanDerWaalsContact C-N 3.33Å; V189-E191 PolarHBondContact O-N 2.76Å; E191-A194 PolarHBondContact O-N 3.41Å; E191-N195 WeakPolarHBondContact O-CB 3.34Å; E191-N195 PolarHBondContact O-N 2.85Å; E191-N195 PolarHBondContact O-ND2 3.23Å; E191-N195 PolarHBondContact O-OD1 2.91Å
192I97.9Very high97.7Very high3 Ų329.1 Ų29.12%0.01515%0.148CC..Hα-helixtrans-62.2-45.2175.8-63-62.8000111.1I24 H141 H188 V189 A194 N195 L196I24-I192 HydrophobicContact CD1-CG2 4.13Å; H141-I192 HydrophobicContact CB-CD1 3.95Å; H188-I192 PolarHBondContact O-N 3.05Å; V189-I192 PolarHBondContact O-N 2.75Å; I192-A194 VanDerWaalsContact C-N 3.28Å; I192-A194 PolarHBondContact O-N 3.19Å; I192-N195 PolarHBondContact O-N 3.29Å; I192-L196 HydrophobicContact CG2-CD1 3.98Å; I192-L196 WeakPolarHBondContact O-CB 3.32Å; I192-L196 PolarHBondContact O-N 2.82Å
193C98.5Very high97.6Very high1 Ų126.7 Ų26.71%0.00714%0.136CC..Hα-helixtrans-58.7-40.2173.9-71.60000111.9V189 L190 D197 S198 F520 I524V189-C193 PolarHBondContact O-N 3.4Å; V189-C193 PolarHBondContact O-SG 3.28Å; L190-C193 PolarHBondContact O-N 2.95Å; C193-D197 CarbonylContact O-C 3.58Å; C193-D197 WeakPolarHBondContact O-CA 3.48Å; C193-D197 PolarHBondContact O-N 3.18Å; C193-S198 WeakPolarHBondContact CA-O 3.38Å; C193-S198 WeakPolarHBondContact CB-O 3.41Å; C193-S198 PolarHBondContact O-N 3.08Å; C193-F520 HydrophobicContact CB-CE2 4.14Å; C193-F520 HydrophobicContact CB-CZ 3.95Å; C193-I524 HydrophobicContact CB-CD1 3.72Å
194A98.4Very high97.4Very high1 Ų127.1 Ų27.11%0.00814%0.136CC..Hα-helixtrans-70.7-42.3179.800000112L190 E191 I192 L196 D197 I524 I527 Q528L190-A194 VanDerWaalsContact O-CB 3.27Å; L190-A194 WeakPolarHBondContact O-CB 3.33Å; L190-A194 PolarHBondContact O-N 2.74Å; E191-A194 PolarHBondContact O-N 3.41Å; I192-A194 VanDerWaalsContact C-N 3.28Å; I192-A194 PolarHBondContact O-N 3.19Å; A194-L196 VanDerWaalsContact C-N 3.3Å; A194-L196 PolarHBondContact O-N 2.92Å; A194-D197 PolarHBondContact O-N 3.4Å; A194-I524 HydrophobicContact CB-CD1 3.81Å; A194-I524 HydrophobicContact CB-CG2 4.3Å; A194-I527 HydrophobicContact CB-CB 3.76Å; A194-I527 HydrophobicContact CB-CD1 4.28Å; A194-I527 HydrophobicContact CB-CG2 3.48Å; A194-I527 VanDerWaalsContact CB-CG2 3.48Å; A194-Q528 HydrophobicContact CB-CG 4.23Å; A194-Q528 WeakPolarHBondContact O-CG 3.31Å; A194-Q528 PolarHBondContact O-NE2 3.24Å
195N98.1Very high97.3Very high15 Ų1527.8 Ų27.88%0.0814%0.143CC..Hα-helixtrans-61.8-39.7176-68.1-19.1000111.1T140 M150 E191 I192T140-N195 HydrophobicContact CG2-CB 4.05Å; T140-N195 WeakPolarHBondContact O-CB 3.4Å; T140-N195 PolarHBondContact O-ND2 3.24Å; M150-N195 VanDerWaalsContact CB-O 3.23Å; M150-N195 WeakPolarHBondContact CB-O 3.24Å; E191-N195 WeakPolarHBondContact O-CB 3.34Å; E191-N195 PolarHBondContact O-N 2.85Å; E191-N195 PolarHBondContact O-ND2 3.23Å; E191-N195 PolarHBondContact O-OD1 2.91Å; I192-N195 PolarHBondContact O-N 3.29Å
196L98.3Very high97.2Very high0 Ų032.6 Ų32.60%016%0.162CC..THydrogen-bonded Turntrans-89.2-1178.6-74.2162.7000114.1I24 I134 C137 T140 M150 I167 I192 A194 S198I24-L196 HydrophobicContact CD1-CB 4.15Å; I24-L196 HydrophobicContact CD1-CD1 3.64Å; I24-L196 HydrophobicContact CG1-CB 4.39Å; I24-L196 HydrophobicContact CG1-CD1 3.83Å; I134-L196 HydrophobicContact CD1-CD2 3.63Å; C137-L196 HydrophobicContact CB-CD1 3.7Å; C137-L196 HydrophobicContact CB-CD2 4.37Å; T140-L196 HydrophobicContact CG2-CD2 3.94Å; T140-L196 HydrophobicContact CG2-CG 3.99Å; M150-L196 HydrophobicContact CG-CD2 4.19Å; I167-L196 HydrophobicContact CG2-CD2 4.22Å; I167-L196 WeakPolarHBondContact CG2-O 3.2Å; I192-L196 HydrophobicContact CG2-CD1 3.98Å; I192-L196 WeakPolarHBondContact O-CB 3.32Å; I192-L196 PolarHBondContact O-N 2.82Å; A194-L196 VanDerWaalsContact C-N 3.3Å; A194-L196 PolarHBondContact O-N 2.92Å; L196-S198 PolarHBondContact O-N 3.02Å; L196-S198 PolarHBondContact O-OG 2.93Å
197D97.9Very high97Very high24 Ų2436 Ų3613%0.12818%0.18CC..THydrogen-bonded Turntrans48.840.4-173.2-165.843000113.6N22 Y153 K157 C193 A194 Q528N22-D197 WeakPolarHBondContact CB-O 3.32Å; N22-D197 PolarHBondContact ND2-O 2.89Å; N22-D197 VanDerWaalsContact ND2-O 3.1Å; N22-D197 PolarHBondContact ND2-OD2 3.32Å; Y153-D197 HydrophobicContact CD1-CB 4.37Å; Y153-D197 HydrophobicContact CE1-CB 3.61Å; Y153-D197 WeakPolarHBondContact CE1-OD2 3.39Å; Y153-D197 PolarHBondContact OH-OD2 3.19Å; Y153-D197 VanDerWaalsContact OH-OD2 3.12Å; K157-D197 WeakPolarHBondContact CD-OD2 3.47Å; K157-D197 IonicContact NZ-OD1 3.28Å; K157-D197 PolarHBondContact NZ-OD1 3.15Å; K157-D197 IonicContact NZ-OD2 2.7Å; C193-D197 CarbonylContact O-C 3.58Å; C193-D197 WeakPolarHBondContact O-CA 3.48Å; C193-D197 PolarHBondContact O-N 3.18Å; A194-D197 PolarHBondContact O-N 3.4Å; D197-Q528 PolarHBondContact OD1-NE2 3.45Å
198S98.1Very high96.8Very high3 Ų336.2 Ų36.22%0.02119%0.185CC..  trans-136.7148.7-163.9-67.50000112.6N22 C193 L196N22-S198 WeakPolarHBondContact O-CA 3.4Å; C193-S198 WeakPolarHBondContact CA-O 3.38Å; C193-S198 WeakPolarHBondContact CB-O 3.41Å; C193-S198 PolarHBondContact O-N 3.08Å; L196-S198 PolarHBondContact O-N 3.02Å; L196-S198 PolarHBondContact O-OG 2.93Å
199V97.7Very high96.7Very high25 Ų2537 Ų3715%0.15219%0.189CC..EExtended strand (participates in β ladder)trans-85.2145.4167.3-70.60000110.7N22 V23 I24 F520N22-V199 VanDerWaalsContact O-CG2 3.3Å; N22-V199 WeakPolarHBondContact O-CG2 3.44Å; N22-V199 PolarHBondContact O-N 3.02Å; V23-V199 CarbonylContact C-O 3.56Å; V23-V199 WeakPolarHBondContact CA-O 3.18Å; V23-V199 HydrophobicContact CG2-CG2 4.03Å; I24-V199 PolarHBondContact N-O 3.44Å; V199-F520 HydrophobicContact CB-CZ 4.49Å; V199-F520 HydrophobicContact CG1-CD1 4.09Å; V199-F520 HydrophobicContact CG1-CE1 3.46Å; V199-F520 VanDerWaalsContact CG1-CE1 3.46Å; V199-F520 HydrophobicContact CG1-CZ 3.85Å
200I97.8Very high96.5Very high9 Ų937.8 Ų37.85%0.04619%0.193CC..EExtended strand (participates in β ladder)trans-92.2130175.7-169.1163.9000111.8I24 W26 P174 V189 I509 V512 Q513I24-I200 HydrophobicContact CB-CB 4.3Å; I24-I200 HydrophobicContact CB-CG1 4.22Å; I24-I200 HydrophobicContact CG2-CD1 4.26Å; I24-I200 HydrophobicContact CG2-CG1 4.11Å; I24-I200 WeakPolarHBondContact O-CA 3.42Å; W26-I200 HydrophobicContact CB-CD1 4.06Å; W26-I200 HydrophobicContact CB-CG1 4.01Å; W26-I200 HydrophobicContact CG-CD1 4.47Å; P174-I200 HydrophobicContact CG-CD1 4.13Å; V189-I200 HydrophobicContact CG1-CG2 4.5Å; I200-I509 HydrophobicContact CD1-CD1 3.96Å; I200-I509 HydrophobicContact CD1-CG1 4.02Å; I200-I509 HydrophobicContact CD1-CG2 4.12Å; I200-I509 HydrophobicContact CG1-CG2 4.32Å; I200-I509 HydrophobicContact CG2-CG2 3.97Å; I200-V512 HydrophobicContact CG2-CG1 4.2Å; I200-Q513 HydrophobicContact CG2-CG 4.14Å; I200-Q513 WeakPolarHBondContact O-CG 3.38Å; I200-Q513 PolarHBondContact O-NE2 3.4Å; I200-Q513 VanDerWaalsContact O-NE2 3.14Å
201V97.2Very high96.1Very high16 Ų1643.4 Ų43.410%0.09722%0.22CC..EExtended strand (participates in β ladder)trans-122.6148.5-179.2-57.90000111.4V13 V23 I24 I25 W26V13-V201 HydrophobicContact CB-CG2 4.11Å; V13-V201 WeakPolarHBondContact O-CG2 3.06Å; V23-V201 HydrophobicContact CG1-CB 4.19Å; V23-V201 HydrophobicContact CG1-CG1 3.84Å; V23-V201 HydrophobicContact CG1-CG2 3.3Å; I24-V201 WeakPolarHBondContact O-CG2 3.13Å; I24-V201 PolarHBondContact O-N 2.82Å; I25-V201 HydrophobicContact CG1-CG2 4.17Å; W26-V201 WeakPolarHBondContact CB-O 3.45Å; W26-V201 PolarHBondContact N-O 3.22Å
202S96Very high95.7Very high21 Ų2146 Ų4615%0.14723%0.232CC..  trans-149.3158.6178.456.20000110.3K204 Q513S202-K204 PolarHBondContact O-N 3.01Å; S202-Q513 PolarHBondContact OG-NE2 3.41Å; S202-Q513 PolarHBondContact OG-OE1 3.43Å
203T94.9Very high95.3Very high13 Ų1350.2 Ų50.28%0.0825%0.25CC..  trans-64.6133.2174.6177.70000110.3E12 L27 Y206 I207 L210E12-T203 VanDerWaalsContact OE2-CA 3.29Å; E12-T203 WeakPolarHBondContact OE2-CA 3.49Å; E12-T203 WeakPolarHBondContact OE2-CB 2.97Å; E12-T203 PolarHBondContact OE2-OG1 3.43Å; L27-T203 HydrophobicContact CD2-CG2 4.43Å; T203-Y206 PolarHBondContact OG1-N 2.96Å; T203-I207 HydrophobicContact CG2-CG1 4.31Å; T203-L210 HydrophobicContact CG2-CB 4.38Å; T203-L210 HydrophobicContact CG2-CD2 3.47Å; T203-L210 VanDerWaalsContact CG2-CD2 3.47Å
204K92.5Very high94.7Very high126 Ų12651.1 Ų51.155%0.54826%0.255SS..SBendtrans-119-39.9173.6-64.8-177-179.1-179.40110.5E12 S202E12-K204 PolarHBondContact OE1-N 3.2Å; E12-K204 PolarHBondContact OE2-N 3.01Å; S202-K204 PolarHBondContact O-N 3.01Å
205N95.3Very high94Very high124 Ų12453.8 Ų53.866%0.66327%0.273SS*.SBendtrans-86.4-24.1-173.8-61.4-43.4000113.1E12E12-N205 PolarHBondContact OE1-N 3.18Å; E12-N205 VanDerWaalsContact OE1-N 3.09Å; E12-N205 PolarHBondContact OE1-ND2 3.46Å; E12-N205 PolarHBondContact OE2-N 2.66Å
206Y96.1Very high93.3Very high102 Ų10262.2 Ų62.240%0.430%0.303SS..  trans-119.132.6-172.8-57.3-76000113.4S8 E12 T203 E209 L210S8-Y206 VanDerWaalsContact CB-CD1 3.48Å; E12-Y206 HydrophobicContact CB-CD2 4.1Å; E12-Y206 HydrophobicContact CB-CE2 4.31Å; E12-Y206 WeakPolarHBondContact OE2-CD2 3.35Å; T203-Y206 PolarHBondContact OG1-N 2.96Å; Y206-E209 PolarHBondContact O-N 2.87Å; Y206-L210 PolarHBondContact O-N 3.45Å; Y206-L210 VanDerWaalsContact O-N 3.07Å
207I93.5Very high92.8Very high75 Ų7563.1 Ų63.139%0.38531%0.309SS..Hα-helixtrans-56.8-45.1175.8-63.3171.4000112.1T203 E209 L210 E211T203-I207 HydrophobicContact CG2-CG1 4.31Å; I207-E209 VanDerWaalsContact C-N 3.34Å; I207-E209 PolarHBondContact O-N 3.11Å; I207-L210 WeakPolarHBondContact O-CB 3.23Å; I207-L210 PolarHBondContact O-N 2.96Å; I207-L210 VanDerWaalsContact O-N 3.11Å; I207-E211 HydrophobicContact CG2-CG 4.29Å; I207-E211 PolarHBondContact O-N 3.43Å
208P94.3Very high92.4Very high94 Ų9468.9 Ų68.961%0.6134%0.335SS*.Hα-helixtrans-61-40179.4-24.935.6000113.3L210 E211 E212P208-L210 VanDerWaalsContact C-N 3.35Å; P208-E211 PolarHBondContact O-N 3.05Å; P208-E212 PolarHBondContact O-N 2.88Å; P208-E212 VanDerWaalsContact O-N 3.08Å
209E94.9Very high92Very high42 Ų4271.6 Ų71.620%0.19635%0.347CS..Hα-helixtrans-64.2-41.4175.3-173.6-169.9163.100110.9R7 S8 Y9 Y206 I207 E212 K213R7-E209 WeakPolarHBondContact CB-OE1 3.23Å; S8-E209 WeakPolarHBondContact CB-OE2 3.45Å; S8-E209 PolarHBondContact N-OE1 3.08Å; S8-E209 PolarHBondContact N-OE2 3.13Å; S8-E209 PolarHBondContact OG-OE2 3.31Å; Y9-E209 HydrophobicContact CD1-CG 4.22Å; Y206-E209 PolarHBondContact O-N 2.87Å; I207-E209 VanDerWaalsContact C-N 3.34Å; I207-E209 PolarHBondContact O-N 3.11Å; E209-E212 PolarHBondContact O-N 2.92Å; E209-K213 HydrophobicContact CG-CG 4.43Å; E209-K213 VanDerWaalsContact O-CG 3.32Å; E209-K213 WeakPolarHBondContact O-CG 3.5Å; E209-K213 PolarHBondContact O-N 3.15Å
210L92.9Very high91.7Very high18 Ų1871.8 Ų71.89%0.09435%0.348CS..Hα-helixtrans-61.8-45.517817763.7000111.8Y9 P28 T203 Y206 I207 P208 E212 K213 V214Y9-L210 HydrophobicContact CD1-CB 4.16Å; Y9-L210 HydrophobicContact CD1-CD1 4.33Å; Y9-L210 HydrophobicContact CD2-CD1 3.96Å; Y9-L210 HydrophobicContact CE1-CD1 4.07Å; Y9-L210 HydrophobicContact CE2-CD1 3.7Å; Y9-L210 HydrophobicContact CG-CB 4.25Å; Y9-L210 HydrophobicContact CG-CD1 4.29Å; P28-L210 HydrophobicContact CG-CD1 3.85Å; P28-L210 HydrophobicContact CG-CD2 3.94Å; P28-L210 HydrophobicContact CG-CG 4.14Å; T203-L210 HydrophobicContact CG2-CB 4.38Å; T203-L210 HydrophobicContact CG2-CD2 3.47Å; T203-L210 VanDerWaalsContact CG2-CD2 3.47Å; Y206-L210 PolarHBondContact O-N 3.45Å; Y206-L210 VanDerWaalsContact O-N 3.07Å; I207-L210 WeakPolarHBondContact O-CB 3.23Å; I207-L210 PolarHBondContact O-N 2.96Å; I207-L210 VanDerWaalsContact O-N 3.11Å; P208-L210 VanDerWaalsContact C-N 3.35Å; L210-E212 VanDerWaalsContact C-N 3.34Å; L210-K213 PolarHBondContact O-N 2.95Å; L210-V214 HydrophobicContact CD1-CB 4.45Å; L210-V214 HydrophobicContact CD1-CG2 3.78Å; L210-V214 WeakPolarHBondContact O-CB 3.38Å; L210-V214 PolarHBondContact O-N 3.29Å
211E90Very high91.3Very high122 Ų12274 Ų7457%0.5736%0.358SS*.Hα-helixtrans-65.8-36.4179.7-69.9-179.5159.200112.2I207 P208I207-E211 HydrophobicContact CG2-CG 4.29Å; I207-E211 PolarHBondContact O-N 3.43Å; P208-E211 PolarHBondContact O-N 3.05Å
212E89.5Confident90.9Very high132 Ų13274 Ų7462%0.61736%0.357SS*.Hα-helixtrans-65.8-41.8174.5-168.6-152.5128.600112.1P208 E209 L210P208-E212 PolarHBondContact O-N 2.88Å; P208-E212 VanDerWaalsContact O-N 3.08Å; E209-E212 PolarHBondContact O-N 2.92Å; L210-E212 VanDerWaalsContact C-N 3.34Å
213K88.8Confident90.5Very high92 Ų9276.8 Ų76.840%0.437%0.369SS..Hα-helixtrans-83.6-17.6-176.6-62.2-50.6-178.7-152.90114E209 L210E209-K213 HydrophobicContact CG-CG 4.43Å; E209-K213 VanDerWaalsContact O-CG 3.32Å; E209-K213 WeakPolarHBondContact O-CG 3.5Å; E209-K213 PolarHBondContact O-N 3.15Å; L210-K213 PolarHBondContact O-N 2.95Å
214V87.4Confident90.3Very high20 Ų2076.8 Ų76.812%0.12137%0.369CS..SBendtrans-129.278.3-178-169.80000109.2P28 T29 L210P28-V214 HydrophobicContact CB-CG1 4.37Å; P28-V214 HydrophobicContact CG-CG1 4.2Å; T29-V214 VanDerWaalsContact O-CG1 3.23Å; T29-V214 WeakPolarHBondContact O-CG1 3.24Å; L210-V214 HydrophobicContact CD1-CB 4.45Å; L210-V214 HydrophobicContact CD1-CG2 3.78Å; L210-V214 WeakPolarHBondContact O-CB 3.38Å; L210-V214 PolarHBondContact O-N 3.29Å
215P82.3Confident90.1Very high57 Ų5776.2 Ų76.237%0.3737%0.368SS..PPolyproline II helixtrans-64.2142.4178.727.9-34.3000110.4
216R84.1Confident89.7Confident192 Ų19277.5 Ų77.573%0.72537%0.368SS*.PPolyproline II helixtrans-90.2138.2172.9-63.7-173.9-175.2-153.12.2109.6E502R216-E502 IonicContact NH1-OE1 3.57Å
217P88.1Confident89.2Confident19 Ų1974.3 Ų74.312%0.12336%0.355CS..PPolyproline II helixtrans-65.9150.2175.928.5-35.4000111.2K219 S471 A474 S479P217-K219 PolarHBondContact O-N 3.19Å; P217-S471 VanDerWaalsContact CG-OG 3.26Å; P217-S471 WeakPolarHBondContact CG-OG 3.42Å; P217-A474 HydrophobicContact CB-CB 3.83Å; P217-A474 HydrophobicContact CG-CB 4.13Å; P217-S479 CarbonylContact C-O 3.4Å; P217-S479 WeakPolarHBondContact CA-O 3.3Å; P217-S479 WeakPolarHBondContact CB-O 3.38Å
218Q89.3Confident88.8Confident144 Ų14478 Ų7867%0.67338%0.381SS*.EExtended strand (participates in β ladder)trans-70.7117.2171.7-172.7178.88.200109.4S479 Y481Q218-S479 PolarHBondContact N-O 2.76Å; Q218-Y481 PolarHBondContact O-N 2.98Å
219K90.4Very high88.7Confident60 Ų6076 Ų7626%0.26137%0.37SS..EExtended strand (participates in β ladder)trans-82.6126.4178.1180158.7-174.1176.50111.3P217 F221 Y481 E495 E499P217-K219 PolarHBondContact O-N 3.19Å; K219-F221 HydrophobicContact CD-CE2 4.45Å; K219-F221 HydrophobicContact CG-CE2 4.28Å; K219-Y481 CarbonylContact C-O 3.52Å; K219-Y481 VanDerWaalsContact CA-O 3.3Å; K219-Y481 WeakPolarHBondContact CA-O 3.36Å; K219-Y481 HydrophobicContact CB-CD1 4.21Å; K219-Y481 HydrophobicContact CD-CD1 3.89Å; K219-Y481 HydrophobicContact CD-CE1 3.93Å; K219-Y481 HydrophobicContact CG-CD1 3.81Å; K219-Y481 HydrophobicContact CG-CE1 4.25Å; K219-E495 WeakPolarHBondContact CE-OE1 3.3Å; K219-E495 IonicContact NZ-OE1 2.82Å; K219-E495 PolarHBondContact NZ-OE1 3.19Å; K219-E499 VanDerWaalsContact CD-OE1 3.31Å; K219-E499 WeakPolarHBondContact CD-OE1 2.99Å; K219-E499 WeakPolarHBondContact CE-OE1 3.47Å; K219-E499 IonicContact NZ-OE1 2.69Å; K219-E499 PolarHBondContact NZ-OE1 3.08Å
220T90.6Very high88.7Confident30 Ų3075.7 Ų75.718%0.18437%0.369CS..EExtended strand (participates in β ladder)trans-124.3135.2176.3610000111.4D222 Q480 Y481 V483T220-D222 PolarHBondContact OG1-OD2 3.44Å; T220-Q480 HydrophobicContact CG2-CG 4.43Å; T220-Q480 PolarHBondContact OG1-NE2 3.45Å; T220-Y481 PolarHBondContact N-O 3Å; T220-V483 PolarHBondContact O-N 3Å
221F88.6Confident88.9Confident56 Ų5675.8 Ų75.825%0.24637%0.371CS..EExtended strand (participates in β ladder)trans-96.9106.1171.6-70.3-89.2000109.1K219 I223 V483 E495 Y496K219-F221 HydrophobicContact CD-CE2 4.45Å; K219-F221 HydrophobicContact CG-CE2 4.28Å; F221-I223 HydrophobicContact CB-CD1 4.31Å; F221-I223 HydrophobicContact CB-CG1 4.06Å; F221-I223 PolarHBondContact O-N 3.43Å; F221-I223 VanDerWaalsContact O-N 3.17Å; F221-V483 HydrophobicContact CD1-CB 4.28Å; F221-E495 HydrophobicContact CE1-CB 3.93Å; F221-E495 HydrophobicContact CE1-CG 3.76Å; F221-E495 HydrophobicContact CZ-CB 4.47Å; F221-E495 HydrophobicContact CZ-CG 4.01Å; F221-Y496 HydrophobicContact CE1-CE1 4.31Å; F221-Y496 AromaticContact CE2-CE1 3.96Å; F221-Y496 HydrophobicContact CE2-CE1 3.96Å; F221-Y496 HydrophobicContact CZ-CD1 4.11Å; F221-Y496 AromaticContact CZ-CE1 3.7Å; F221-Y496 HydrophobicContact CZ-CE1 3.7Å
222D88.6Confident89.2Confident15 Ų1570 Ų708%0.0834%0.344CS..EExtended strand (participates in β ladder)trans-90.776.8-178.9-77.3-57.2000109.1T220 K357 S482 V483 V484 A485T220-D222 PolarHBondContact OG1-OD2 3.44Å; D222-K357 HydrophobicContact CB-CD 4.3Å; D222-K357 HydrophobicContact CB-CG 3.95Å; D222-K357 WeakPolarHBondContact OD1-CE 3.5Å; D222-K357 IonicContact OD1-NZ 3.21Å; D222-K357 PolarHBondContact OD1-NZ 3.07Å; D222-S482 WeakPolarHBondContact OD2-CB 3.44Å; D222-S482 PolarHBondContact OD2-OG 3.29Å; D222-V483 PolarHBondContact N-O 3.42Å; D222-V484 HydrophobicContact CB-CG2 4.05Å; D222-A485 PolarHBondContact O-N 2.84Å; D222-A485 VanDerWaalsContact O-N 3.15Å
223I88.9Confident89.5Confident80 Ų8063.7 Ų63.741%0.4132%0.315SS..EExtended strand (participates in β ladder)trans-80.6129.8-172.6-55178.6000110.7F221 A485 K487 I492F221-I223 HydrophobicContact CB-CD1 4.31Å; F221-I223 HydrophobicContact CB-CG1 4.06Å; F221-I223 PolarHBondContact O-N 3.43Å; F221-I223 VanDerWaalsContact O-N 3.17Å; I223-A485 CarbonylContact C-O 2.96Å; I223-A485 VanDerWaalsContact CA-O 3.31Å; I223-A485 WeakPolarHBondContact CA-O 3.44Å; I223-K487 HydrophobicContact CG2-CB 3.63Å; I223-K487 HydrophobicContact CG2-CG 4.17Å; I223-I492 HydrophobicContact CB-CD1 4.44Å; I223-I492 HydrophobicContact CD1-CD1 3.82Å; I223-I492 HydrophobicContact CG1-CD1 3.71Å; I223-I492 HydrophobicContact CG2-CD1 4.02Å
224V90.6Very high89.9Confident13 Ų1363.5 Ų63.58%0.07932%0.318CS..EExtended strand (participates in β ladder)trans-114.6149.7173-56.80000111.9P353 K354 K357 A485 Q486 K487V224-P353 HydrophobicContact CB-CB 4.16Å; V224-P353 HydrophobicContact CB-CG 4.49Å; V224-P353 HydrophobicContact CG2-CB 4.38Å; V224-P353 HydrophobicContact CG2-CG 4.26Å; V224-K354 HydrophobicContact CG2-CB 4.49Å; V224-K354 HydrophobicContact CG2-CG 3.63Å; V224-K357 HydrophobicContact CG1-CB 3.38Å; V224-K357 HydrophobicContact CG1-CD 4.43Å; V224-K357 HydrophobicContact CG1-CG 3.69Å; V224-A485 PolarHBondContact N-O 3.2Å; V224-Q486 HydrophobicContact CG2-CB 4.48Å; V224-Q486 CarbonylContact O-C 3.59Å; V224-Q486 WeakPolarHBondContact O-CA 3.24Å; V224-K487 PolarHBondContact O-N 3.33Å
225E89Confident90.5Very high113 Ų11363.6 Ų63.653%0.52832%0.317SS..PPolyproline II helixtrans-71.2158.1170-65.1-64.2166.400110.9P353 K487E225-P353 VanDerWaalsContact O-CG 3.28Å; E225-P353 WeakPolarHBondContact O-CG 3.41Å; E225-K487 WeakPolarHBondContact OE1-CD 3.34Å; E225-K487 IonicContact OE1-NZ 2.76Å; E225-K487 PolarHBondContact OE1-NZ 3.01Å; E225-K487 VanDerWaalsContact OE2-CD 3.29Å; E225-K487 WeakPolarHBondContact OE2-CD 3.41Å; E225-K487 IonicContact OE2-NZ 3.83Å
226K85.1Confident91.2Very high151 Ų15160.9 Ų60.966%0.65730%0.3SS*.PPolyproline II helixtrans-65.9151.7172.8-167.1176178.2-176.10109.5T228K226-T228 PolarHBondContact O-N 3.14Å
227R87Confident91.9Very high36 Ų3655 Ų5514%0.13628%0.279CS..PPolyproline II helixtrans-51.4133.8166.5-63-176.8-166.3176.90.4109.7S229 D230 N299 N352 P353R227-S229 VanDerWaalsContact C-N 3.27Å; R227-D230 IonicContact CZ-OD1 3.88Å; R227-D230 IonicContact NH1-OD1 2.76Å; R227-D230 PolarHBondContact NH1-OD1 3.35Å; R227-N299 PolarHBondContact NH1-ND2 3.42Å; R227-N299 PolarHBondContact NH1-OD1 3.35Å; R227-N299 PolarHBondContact NH2-O 3.36Å; R227-N299 PolarHBondContact NH2-OD1 2.97Å; R227-N352 VanDerWaalsContact NH2-CB 3.31Å; R227-N352 PolarHBondContact NH2-ND2 2.92Å; R227-P353 HydrophobicContact CG-CG 4.41Å
228T84.9Confident92.4Very high151 Ų15159.1 Ų59.193%0.92629%0.292SS*.SBendtrans-67.2-32.4174.9490000111.5K226K226-T228 PolarHBondContact O-N 3.14Å
229S91.8Very high92.8Very high52 Ų5252.2 Ų52.236%0.36426%0.26SS..  trans-146.6141.5175.7-177.30000109.8R227R227-S229 VanDerWaalsContact C-N 3.27Å
230D94.6Very high93.2Very high36 Ų3649.4 Ų49.419%0.19325%0.248CC..  trans-134.866.3179.3-174.727.3000110.8R227 F232 G233 D234 N299R227-D230 IonicContact CZ-OD1 3.88Å; R227-D230 IonicContact NH1-OD1 2.76Å; R227-D230 PolarHBondContact NH1-OD1 3.35Å; D230-F232 PolarHBondContact O-N 3.37Å; D230-G233 PolarHBondContact O-N 2.93Å; D230-G233 PolarHBondContact OD1-N 3.47Å; D230-D234 PolarHBondContact O-N 3.38Å; D230-N299 PolarHBondContact OD1-ND2 3.37Å; D230-N299 PolarHBondContact OD2-ND2 3.48Å
231P96.8Very high93.4Very high20 Ų2053.6 Ų53.613%0.1327%0.265CS..Hα-helixtrans-61.6-31.5-174.325.8-34.3000112.5H235 F344 Y350P231-H235 WeakPolarHBondContact O-CB 3.44Å; P231-H235 PolarHBondContact O-N 3.43Å; P231-F344 HydrophobicContact CB-CD1 3.89Å; P231-F344 HydrophobicContact CB-CE1 3.94Å; P231-F344 HydrophobicContact CB-CG 4.21Å; P231-F344 HydrophobicContact CB-CZ 4.26Å; P231-F344 HydrophobicContact CG-CD1 4Å; P231-F344 HydrophobicContact CG-CE1 4.44Å; P231-F344 HydrophobicContact CG-CG 4.38Å; P231-Y350 HydrophobicContact CG-CD1 3.92Å; P231-Y350 HydrophobicContact CG-CD2 3.54Å; P231-Y350 HydrophobicContact CG-CE1 3.91Å; P231-Y350 HydrophobicContact CG-CE2 3.56Å; P231-Y350 HydrophobicContact CG-CG 3.73Å
232F97.4Very high93.9Very high0 Ų054.6 Ų54.60%027%0.271CS..Hα-helixtrans-62.2-49.9173.1-179.8-92.8000111.8D230 H235 I236 N299 M304 A307 L341 F344 A345D230-F232 PolarHBondContact O-N 3.37Å; F232-H235 PolarHBondContact O-N 2.92Å; F232-I236 HydrophobicContact CD1-CD1 3.96Å; F232-I236 HydrophobicContact CE1-CD1 3.28Å; F232-I236 HydrophobicContact CE1-CG1 4.32Å; F232-I236 HydrophobicContact CE2-CD1 4.4Å; F232-I236 HydrophobicContact CZ-CD1 3.56Å; F232-I236 HydrophobicContact CZ-CG1 4.47Å; F232-I236 PolarHBondContact O-N 3.46Å; F232-N299 HydrophobicContact CD1-CB 4.22Å; F232-N299 HydrophobicContact CE1-CB 4.17Å; F232-M304 HydrophobicContact CB-CG 4.01Å; F232-M304 HydrophobicContact CB-SD 3.51Å; F232-M304 VanDerWaalsContact CB-SD 3.51Å; F232-M304 HydrophobicContact CD1-CB 4.27Å; F232-M304 HydrophobicContact CD1-CG 4.1Å; F232-M304 HydrophobicContact CD2-CB 4.42Å; F232-M304 HydrophobicContact CG-CB 4.16Å; F232-M304 HydrophobicContact CG-CG 4.04Å; F232-M304 HydrophobicContact CG-SD 4.14Å; F232-A307 HydrophobicContact CE1-CB 3.59Å; F232-A307 HydrophobicContact CZ-CB 3.81Å; F232-L341 HydrophobicContact CD2-CD2 3.96Å; F232-L341 HydrophobicContact CE2-CB 4.33Å; F232-L341 HydrophobicContact CE2-CD2 3.83Å; F232-F344 HydrophobicContact CB-CB 3.99Å; F232-F344 HydrophobicContact CD2-CB 4.29Å; F232-A345 HydrophobicContact CD2-CB 3.99Å; F232-A345 HydrophobicContact CE2-CB 3.98Å
233G96.6Very high94.3Very high0 Ų053.9 Ų53.90%027%0.267CS..Hα-helixtrans-64.6-39.917800000112.7D230 I236 K237D230-G233 PolarHBondContact O-N 2.93Å; D230-G233 PolarHBondContact OD1-N 3.47Å; G233-I236 PolarHBondContact O-N 3.07Å; G233-K237 WeakPolarHBondContact O-CG 3.35Å; G233-K237 PolarHBondContact O-N 2.94Å
234D97.3Very high94.6Very high89 Ų8951.8 Ų51.848%0.47626%0.255SS..Hα-helixtrans-66.8-40177.6-67.2-27.2000111.8D230 K237 W238D230-D234 PolarHBondContact O-N 3.38Å; D234-K237 PolarHBondContact O-N 3.46Å; D234-K237 IonicContact OD1-NZ 3.66Å; D234-W238 PolarHBondContact O-N 3.18Å
235H98.1Very high94.7Very high22 Ų2253.9 Ų53.910%0.10228%0.28CS..Hα-helixtrans-65.4-42.5175.4-17093.8000111.9P231 F232 K237 W238 M239 N337 E340 L341 F344P231-H235 WeakPolarHBondContact O-CB 3.44Å; P231-H235 PolarHBondContact O-N 3.43Å; F232-H235 PolarHBondContact O-N 2.92Å; H235-K237 VanDerWaalsContact C-N 3.33Å; H235-K237 PolarHBondContact O-N 3.38Å; H235-W238 WeakPolarHBondContact O-CB 3.5Å; H235-W238 PolarHBondContact O-N 3.28Å; H235-M239 WeakPolarHBondContact O-CG 3.27Å; H235-M239 PolarHBondContact O-N 3.07Å; H235-N337 PolarHBondContact CE1-OD1 3.48Å; H235-N337 VanDerWaalsContact CE1-OD1 3.23Å; H235-N337 WeakPolarHBondContact NE2-CB 3.47Å; H235-N337 PolarHBondContact NE2-OD1 3.4Å; H235-N337 VanDerWaalsContact NE2-OD1 3.12Å; H235-E340 IonicContact CE1-OE2 3.06Å; H235-E340 PolarHBondContact CE1-OE2 2.95Å; H235-E340 IonicContact ND1-OE2 3.57Å; H235-L341 HydrophobicContact CB-CD2 4.4Å; H235-F344 HydrophobicContact CB-CD2 4.27Å; H235-F344 HydrophobicContact CB-CE2 4.03Å
236I98.2Very high95Very high0 Ų052 Ų520%027%0.27CS..Hα-helixtrans-59.2-44.5172.6-72.2179.2000111.2F232 G233 W238 M239 M240 Y292 A295 L296 L311 L341F232-I236 HydrophobicContact CD1-CD1 3.96Å; F232-I236 HydrophobicContact CE1-CD1 3.28Å; F232-I236 HydrophobicContact CE1-CG1 4.32Å; F232-I236 HydrophobicContact CE2-CD1 4.4Å; F232-I236 HydrophobicContact CZ-CD1 3.56Å; F232-I236 HydrophobicContact CZ-CG1 4.47Å; F232-I236 PolarHBondContact O-N 3.46Å; G233-I236 PolarHBondContact O-N 3.07Å; I236-W238 VanDerWaalsContact C-N 3.29Å; I236-W238 PolarHBondContact O-N 3.5Å; I236-M239 PolarHBondContact O-N 3.32Å; I236-M240 HydrophobicContact CG2-CG 4.31Å; I236-M240 HydrophobicContact CG2-SD 3.95Å; I236-M240 VanDerWaalsContact O-CG 3.31Å; I236-M240 WeakPolarHBondContact O-CG 3.44Å; I236-M240 PolarHBondContact O-N 3.1Å; I236-Y292 HydrophobicContact CG2-CD1 3.87Å; I236-Y292 HydrophobicContact CG2-CG 4.35Å; I236-A295 HydrophobicContact CD1-CB 4.03Å; I236-L296 HydrophobicContact CB-CD2 3.92Å; I236-L296 HydrophobicContact CB-CG 4.37Å; I236-L296 HydrophobicContact CD1-CD2 4.44Å; I236-L296 HydrophobicContact CG2-CD1 4.06Å; I236-L296 HydrophobicContact CG2-CD2 3.81Å; I236-L296 HydrophobicContact CG2-CG 3.68Å; I236-L311 HydrophobicContact CD1-CD1 3.89Å; I236-L311 HydrophobicContact CG1-CD1 4.41Å; I236-L341 HydrophobicContact CG1-CD2 3.92Å
237K98.2Very high95.4Very high67 Ų6745.3 Ų45.329%0.29124%0.241SC..Hα-helixtrans-61.6-38.4177.9-72.5169.8-173.2169.50111.8G233 D234 H235 M240 Q241 C258 L296G233-K237 WeakPolarHBondContact O-CG 3.35Å; G233-K237 PolarHBondContact O-N 2.94Å; D234-K237 PolarHBondContact O-N 3.46Å; D234-K237 IonicContact OD1-NZ 3.66Å; H235-K237 VanDerWaalsContact C-N 3.33Å; H235-K237 PolarHBondContact O-N 3.38Å; K237-M240 WeakPolarHBondContact O-CB 3.21Å; K237-M240 PolarHBondContact O-N 3.03Å; K237-Q241 WeakPolarHBondContact O-CG 3.45Å; K237-Q241 PolarHBondContact O-N 3.37Å; K237-C258 HydrophobicContact CG-CB 4.3Å; K237-L296 HydrophobicContact CG-CD1 4.02Å; K237-L296 HydrophobicContact CG-CD2 4.47Å
238W98.1Very high95.1Very high106 Ų10648.3 Ų48.340%0.40227%0.267SS..Hα-helixtrans-62.1-45.4173.5171.783000111.9D234 H235 I236 M240 Q241 Q242 N337D234-W238 PolarHBondContact O-N 3.18Å; H235-W238 WeakPolarHBondContact O-CB 3.5Å; H235-W238 PolarHBondContact O-N 3.28Å; I236-W238 VanDerWaalsContact C-N 3.29Å; I236-W238 PolarHBondContact O-N 3.5Å; W238-M240 VanDerWaalsContact C-N 3.29Å; W238-M240 PolarHBondContact O-N 3.38Å; W238-Q241 WeakPolarHBondContact O-CA 3.43Å; W238-Q241 WeakPolarHBondContact O-CB 3.26Å; W238-Q241 PolarHBondContact O-N 2.99Å; W238-Q242 HydrophobicContact CD2-CG 4.28Å; W238-Q242 HydrophobicContact CH2-CG 4.06Å; W238-Q242 HydrophobicContact CZ2-CG 3.79Å; W238-Q242 HydrophobicContact CZ3-CG 4.42Å; W238-Q242 PolarHBondContact O-N 3.22Å; W238-N337 WeakPolarHBondContact CZ3-OD1 3.23Å
239M98.3Very high95.1Very high0 Ų043.9 Ų43.90%024%0.238CC..Hα-helixtrans-60.5-40.1174.8-63.2174.877.800111.7H235 I236 Q241 Q242 I243 Y292 L333 F334 N337 L341H235-M239 WeakPolarHBondContact O-CG 3.27Å; H235-M239 PolarHBondContact O-N 3.07Å; I236-M239 PolarHBondContact O-N 3.32Å; M239-Q241 VanDerWaalsContact C-N 3.29Å; M239-Q241 PolarHBondContact O-N 3.12Å; M239-Q242 WeakPolarHBondContact O-CB 3.36Å; M239-Q242 PolarHBondContact O-N 2.9Å; M239-Q242 VanDerWaalsContact O-N 3.15Å; M239-I243 WeakPolarHBondContact O-CG1 3.3Å; M239-I243 PolarHBondContact O-N 3.34Å; M239-I243 VanDerWaalsContact O-N 3.12Å; M239-Y292 HydrophobicContact CB-CE1 4.45Å; M239-Y292 HydrophobicContact CE-CE1 3.82Å; M239-Y292 WeakPolarHBondContact CE-OH 3.46Å; M239-Y292 HydrophobicContact SD-CE1 3.99Å; M239-L333 HydrophobicContact CB-CD2 4.38Å; M239-L333 HydrophobicContact CE-CG 4.01Å; M239-L333 WeakPolarHBondContact CE-O 3.11Å; M239-F334 HydrophobicContact CE-CD2 4.5Å; M239-N337 HydrophobicContact CE-CB 3.79Å; M239-N337 HydrophobicContact SD-CB 3.97Å; M239-L341 HydrophobicContact CE-CD1 4.43Å; M239-L341 HydrophobicContact SD-CD1 3.84Å; M239-L341 HydrophobicContact SD-CG 4.43Å
240M98.1Very high94.8Very high0 Ų042.4 Ų42.40%023%0.227CC..Hα-helixtrans-61.3-37.3174.4-67.3173.676.300111.9I236 K237 W238 I243 H244 C258 Y263 L289 Y292 N293 L296I236-M240 HydrophobicContact CG2-CG 4.31Å; I236-M240 HydrophobicContact CG2-SD 3.95Å; I236-M240 VanDerWaalsContact O-CG 3.31Å; I236-M240 WeakPolarHBondContact O-CG 3.44Å; I236-M240 PolarHBondContact O-N 3.1Å; K237-M240 WeakPolarHBondContact O-CB 3.21Å; K237-M240 PolarHBondContact O-N 3.03Å; W238-M240 VanDerWaalsContact C-N 3.29Å; W238-M240 PolarHBondContact O-N 3.38Å; M240-I243 PolarHBondContact O-N 3.38Å; M240-H244 VanDerWaalsContact O-CG 3.32Å; M240-H244 PolarHBondContact O-N 2.83Å; M240-H244 PolarHBondContact O-ND1 2.98Å; M240-C258 HydrophobicContact CE-CB 3.78Å; M240-C258 WeakPolarHBondContact CE-SG 3.38Å; M240-C258 HydrophobicContact SD-CB 3.97Å; M240-Y263 HydrophobicContact CE-CD1 4.12Å; M240-Y263 HydrophobicContact CE-CE1 3.25Å; M240-Y263 HydrophobicContact CE-CE2 4.45Å; M240-Y263 VanDerWaalsContact CE-CZ 3.44Å; M240-Y263 VanDerWaalsContact CE-OH 3.28Å; M240-Y263 WeakPolarHBondContact CE-OH 3.36Å; M240-L289 HydrophobicContact CB-CD2 3.8Å; M240-L289 HydrophobicContact CE-CD2 4.23Å; M240-L289 HydrophobicContact CG-CD2 3.98Å; M240-Y292 HydrophobicContact CG-CG 4.1Å; M240-N293 HydrophobicContact CE-CB 4.21Å; M240-L296 HydrophobicContact SD-CD1 3.67Å
241Q96.4Very high94.4Very high119 Ų11946 Ų4656%0.55625%0.252SS*.Hα-helixtrans-65.6-37.2173.6-69.9169.4-7.100112.4K237 W238 M239 I243 H244 G245K237-Q241 WeakPolarHBondContact O-CG 3.45Å; K237-Q241 PolarHBondContact O-N 3.37Å; W238-Q241 WeakPolarHBondContact O-CA 3.43Å; W238-Q241 WeakPolarHBondContact O-CB 3.26Å; W238-Q241 PolarHBondContact O-N 2.99Å; M239-Q241 VanDerWaalsContact C-N 3.29Å; M239-Q241 PolarHBondContact O-N 3.12Å; Q241-I243 VanDerWaalsContact C-N 3.29Å; Q241-I243 PolarHBondContact O-N 2.68Å; Q241-H244 WeakPolarHBondContact O-CB 3.36Å; Q241-H244 PolarHBondContact O-N 3.37Å; Q241-G245 PolarHBondContact O-N 2.74Å
242Q97.4Very high94Very high76 Ų7650.2 Ų50.236%0.35527%0.274SS..Hα-helixtrans-61.1-41.1173.7-59.7-48.6-57.700111.1W238 M239 G245 F246 L333W238-Q242 HydrophobicContact CD2-CG 4.28Å; W238-Q242 HydrophobicContact CH2-CG 4.06Å; W238-Q242 HydrophobicContact CZ2-CG 3.79Å; W238-Q242 HydrophobicContact CZ3-CG 4.42Å; W238-Q242 PolarHBondContact O-N 3.22Å; M239-Q242 WeakPolarHBondContact O-CB 3.36Å; M239-Q242 PolarHBondContact O-N 2.9Å; M239-Q242 VanDerWaalsContact O-N 3.15Å; Q242-G245 PolarHBondContact O-N 3.06Å; Q242-F246 PolarHBondContact O-N 3.06Å; Q242-L333 HydrophobicContact CB-CD1 4.28Å; Q242-L333 HydrophobicContact CB-CD2 4.08Å; Q242-L333 HydrophobicContact CG-CD1 4.37Å
243I97.3Very high93.7Very high0 Ų051.3 Ų51.30%028%0.28CS..Hα-helixtrans-67-39175.9-60.7169.9000111.3M239 M240 Q241 G245 F246 M247 C285 L289 Y292 F329 L330 L333M239-I243 WeakPolarHBondContact O-CG1 3.3Å; M239-I243 PolarHBondContact O-N 3.34Å; M239-I243 VanDerWaalsContact O-N 3.12Å; M240-I243 PolarHBondContact O-N 3.38Å; Q241-I243 VanDerWaalsContact C-N 3.29Å; Q241-I243 PolarHBondContact O-N 2.68Å; I243-G245 VanDerWaalsContact C-N 3.33Å; I243-G245 PolarHBondContact O-N 3.39Å; I243-F246 PolarHBondContact O-N 3.37Å; I243-M247 HydrophobicContact CG2-CE 4.24Å; I243-M247 WeakPolarHBondContact O-CG 3.36Å; I243-M247 PolarHBondContact O-N 3.19Å; I243-C285 HydrophobicContact CG2-CB 3.76Å; I243-L289 HydrophobicContact CB-CD2 3.89Å; I243-L289 HydrophobicContact CB-CG 4.35Å; I243-L289 HydrophobicContact CD1-CD2 4.2Å; I243-L289 HydrophobicContact CG2-CD1 4.16Å; I243-L289 HydrophobicContact CG2-CD2 3.9Å; I243-L289 HydrophobicContact CG2-CG 3.78Å; I243-Y292 HydrophobicContact CD1-CD2 3.8Å; I243-Y292 HydrophobicContact CD1-CE2 3.51Å; I243-F329 HydrophobicContact CG1-CE1 4.26Å; I243-L330 HydrophobicContact CD1-CD2 3.86Å; I243-L330 HydrophobicContact CG1-CD2 3.82Å; I243-L330 HydrophobicContact CG2-CD2 4.03Å; I243-L333 HydrophobicContact CD1-CD2 4.12Å; I243-L333 HydrophobicContact CG1-CD2 3.68Å
244H95.2Very high93.4Very high37 Ų3760.3 Ų60.317%0.17131%0.314CS..Hα-helixtrans-60-42.4172.8-69.1156.7000112.4M240 Q241 M247 L249 L255 Y263 L289M240-H244 VanDerWaalsContact O-CG 3.32Å; M240-H244 PolarHBondContact O-N 2.83Å; M240-H244 PolarHBondContact O-ND1 2.98Å; Q241-H244 WeakPolarHBondContact O-CB 3.36Å; Q241-H244 PolarHBondContact O-N 3.37Å; H244-M247 WeakPolarHBondContact O-CG 3.36Å; H244-L249 HydrophobicContact CB-CD1 3.96Å; H244-L255 VanDerWaalsContact NE2-CD1 3.33Å; H244-L255 WeakPolarHBondContact NE2-CD1 3.26Å; H244-Y263 PolarHBondContact CE1-OH 2.92Å; H244-Y263 VanDerWaalsContact CE1-OH 3.23Å; H244-Y263 AromaticContact NE2-CZ 3.9Å; H244-Y263 PolarHBondContact NE2-OH 2.87Å; H244-L289 WeakPolarHBondContact NE2-CD1 3.38Å
245G93.5Very high93.2Very high57 Ų5758 Ų5859%0.58830%0.302SS*.Hα-helixtrans-63.3-44.617500000112.3Q241 Q242 I243 M247Q241-G245 PolarHBondContact O-N 2.74Å; Q242-G245 PolarHBondContact O-N 3.06Å; I243-G245 VanDerWaalsContact C-N 3.33Å; I243-G245 PolarHBondContact O-N 3.39Å; G245-M247 PolarHBondContact O-N 2.83Å
246F95.3Very high93.1Very high72 Ų7262.7 Ų62.732%0.31632%0.319SS..Hα-helixtrans-63.5-41.2178.7-179-99000112.9Q242 I243 S248 L281 T326 F329Q242-F246 PolarHBondContact O-N 3.06Å; I243-F246 PolarHBondContact O-N 3.37Å; F246-S248 VanDerWaalsContact C-N 3.32Å; F246-S248 PolarHBondContact O-N 2.83Å; F246-L281 HydrophobicContact CD1-CD2 4.37Å; F246-L281 HydrophobicContact CE1-CD1 3.95Å; F246-L281 HydrophobicContact CE1-CD2 4.19Å; F246-L281 HydrophobicContact CE1-CG 3.95Å; F246-L281 HydrophobicContact CZ-CD1 4.27Å; F246-T326 HydrophobicContact CE1-CG2 3.94Å; F246-F329 HydrophobicContact CB-CD1 4.06Å; F246-F329 HydrophobicContact CB-CE1 3.43Å; F246-F329 VanDerWaalsContact CB-CE1 3.43Å; F246-F329 HydrophobicContact CB-CE2 4.4Å; F246-F329 HydrophobicContact CB-CZ 3.63Å; F246-F329 AromaticContact CD1-CD1 3.6Å; F246-F329 HydrophobicContact CD1-CD1 3.6Å; F246-F329 AromaticContact CD1-CE1 3.82Å; F246-F329 HydrophobicContact CD1-CE1 3.82Å; F246-F329 HydrophobicContact CD1-CG 4.34Å; F246-F329 HydrophobicContact CD2-CB 4.49Å; F246-F329 AromaticContact CD2-CD1 3.79Å; F246-F329 HydrophobicContact CD2-CD1 3.79Å; F246-F329 HydrophobicContact CD2-CD2 4.01Å; F246-F329 AromaticContact CD2-CE1 3.98Å; F246-F329 HydrophobicContact CD2-CE1 3.98Å; F246-F329 HydrophobicContact CD2-CE2 4.17Å; F246-F329 AromaticContact CD2-CG 3.81Å; F246-F329 HydrophobicContact CD2-CG 3.81Å; F246-F329 HydrophobicContact CD2-CZ 4.16Å; F246-F329 AromaticContact CE1-CD1 3.94Å; F246-F329 HydrophobicContact CE1-CD1 3.94Å; F246-F329 HydrophobicContact CE1-CG 4.4Å; F246-F329 HydrophobicContact CE2-CB 4.05Å; F246-F329 HydrophobicContact CE2-CD1 4.11Å; F246-F329 HydrophobicContact CE2-CD2 4.3Å; F246-F329 AromaticContact CE2-CG 3.87Å; F246-F329 HydrophobicContact CE2-CG 3.87Å; F246-F329 AromaticContact CG-CD1 3.52Å; F246-F329 HydrophobicContact CG-CD1 3.52Å; F246-F329 HydrophobicContact CG-CD2 4.47Å; F246-F329 AromaticContact CG-CE1 3.46Å; F246-F329 HydrophobicContact CG-CE1 3.46Å; F246-F329 VanDerWaalsContact CG-CE1 3.46Å; F246-F329 HydrophobicContact CG-CE2 4.41Å; F246-F329 HydrophobicContact CG-CG 4.05Å; F246-F329 AromaticContact CG-CZ 3.93Å; F246-F329 HydrophobicContact CG-CZ 3.93Å; F246-F329 HydrophobicContact CZ-CB 4.07Å; F246-F329 HydrophobicContact CZ-CD1 4.17Å; F246-F329 HydrophobicContact CZ-CG 4.18Å
247M92.1Very high93Very high12 Ų1269.4 Ų69.46%0.05935%0.35CS..Hα-helixtrans-75-16.3-175.369.916846.200115.5I243 H244 G245 L249 L270 L281 L282 C285 L289I243-M247 HydrophobicContact CG2-CE 4.24Å; I243-M247 WeakPolarHBondContact O-CG 3.36Å; I243-M247 PolarHBondContact O-N 3.19Å; H244-M247 WeakPolarHBondContact O-CG 3.36Å; G245-M247 PolarHBondContact O-N 2.83Å; M247-L249 HydrophobicContact CG-CG 4.21Å; M247-L249 HydrophobicContact SD-CD1 4.27Å; M247-L249 HydrophobicContact SD-CD2 4.16Å; M247-L249 HydrophobicContact SD-CG 3.68Å; M247-L270 HydrophobicContact CE-CD2 4.23Å; M247-L270 HydrophobicContact SD-CD2 3.99Å; M247-L281 HydrophobicContact CB-CD2 4.01Å; M247-L282 HydrophobicContact CE-CD1 4.47Å; M247-L282 HydrophobicContact SD-CD1 4.13Å; M247-C285 HydrophobicContact CB-CB 4.13Å; M247-C285 HydrophobicContact CE-CB 3.22Å; M247-L289 HydrophobicContact CE-CD1 3.47Å; M247-L289 VanDerWaalsContact CE-CD1 3.47Å; M247-L289 HydrophobicContact SD-CD1 4.43Å
248S81.1Confident92.9Very high98 Ų9867.5 Ų67.569%0.68535%0.345SS*.THydrogen-bonded Turntrans49.170.1-171.1-63.10000112F246F246-S248 VanDerWaalsContact C-N 3.32Å; F246-S248 PolarHBondContact O-N 2.83Å
249L85.9Confident92.6Very high58 Ų5863.3 Ų63.330%0.30434%0.335SS..  trans-42.1130.2-177.3-99.1146.4000112.9H244 M247 V253 L255 L270H244-L249 HydrophobicContact CB-CD1 3.96Å; M247-L249 HydrophobicContact CG-CG 4.21Å; M247-L249 HydrophobicContact SD-CD1 4.27Å; M247-L249 HydrophobicContact SD-CD2 4.16Å; M247-L249 HydrophobicContact SD-CG 3.68Å; L249-V253 HydrophobicContact CD2-CB 4.13Å; L249-V253 HydrophobicContact CD2-CG1 3.71Å; L249-L255 HydrophobicContact CD1-CD1 4.06Å; L249-L255 HydrophobicContact CD2-CD1 3.84Å; L249-L255 HydrophobicContact CD2-CG 3.95Å; L249-L270 HydrophobicContact CD2-CD2 4.35Å
250P84.8Confident92.2Very high21 Ų2164 Ų6414%0.13634%0.339CS..  trans-55.4137.3176.7-25.833.6000111.5D252 V253 L282P250-D252 VanDerWaalsContact CB-OD1 3.28Å; P250-D252 WeakPolarHBondContact CB-OD1 3.27Å; P250-D252 PolarHBondContact O-N 3.43Å; P250-V253 HydrophobicContact CB-CB 4.47Å; P250-V253 HydrophobicContact CB-CG2 3.92Å; P250-V253 HydrophobicContact CG-CG2 4.17Å; P250-V253 PolarHBondContact O-N 2.78Å; P250-L282 HydrophobicContact CG-CD2 4.42Å
251P85.6Confident91.8Very high111 Ų11167 Ų6772%0.72135%0.353SS*.THydrogen-bonded Turntrans-59.8-23.6-172.9-2633.9000114.8R254P251-R254 PolarHBondContact O-NH1 3.31Å; P251-R254 PolarHBondContact O-NH2 2.93Å
252D90.1Very high91.6Very high109 Ų10965 Ų6558%0.58334%0.343SS*.THydrogen-bonded Turntrans-85.5-10.517965.2-58.2000113.5P250 R273P250-D252 VanDerWaalsContact CB-OD1 3.28Å; P250-D252 WeakPolarHBondContact CB-OD1 3.27Å; P250-D252 PolarHBondContact O-N 3.43Å; D252-R273 IonicContact OD1-CZ 2.66Å; D252-R273 IonicContact OD1-NH1 3.23Å; D252-R273 PolarHBondContact OD1-NH1 3.36Å; D252-R273 IonicContact OD1-NH2 3.49Å; D252-R273 PolarHBondContact OD1-NH2 2.93Å; D252-R273 IonicContact OD2-CZ 2.82Å; D252-R273 IonicContact OD2-NH1 3.78Å; D252-R273 PolarHBondContact OD2-NH1 3.1Å; D252-R273 IonicContact OD2-NH2 3.15Å; D252-R273 PolarHBondContact OD2-NH2 3.34Å
253V89Confident91.5Very high24 Ų2461.3 Ų61.315%0.14533%0.326CS..  trans-90.1134.7-180176.60000110.2L249 P250 L255 L270 R273L249-V253 HydrophobicContact CD2-CB 4.13Å; L249-V253 HydrophobicContact CD2-CG1 3.71Å; P250-V253 HydrophobicContact CB-CB 4.47Å; P250-V253 HydrophobicContact CB-CG2 3.92Å; P250-V253 HydrophobicContact CG-CG2 4.17Å; P250-V253 PolarHBondContact O-N 2.78Å; V253-L255 HydrophobicContact CG1-CD2 3.77Å; V253-L255 HydrophobicContact CG1-CG 4.19Å; V253-L270 HydrophobicContact CG1-CD1 4.19Å; V253-L270 HydrophobicContact CG2-CD1 4.13Å; V253-R273 VanDerWaalsContact CG2-NH1 3.27Å
254R91.7Very high91.4Very high188 Ų18863.3 Ų63.371%0.70934%0.336SS*.  trans-126.3113.6170-65.2-67.7178.6-85.4-4.4108.1P251P251-R254 PolarHBondContact O-NH1 3.31Å; P251-R254 PolarHBondContact O-NH2 2.93Å
255L93.6Very high91.4Very high42 Ų4263.6 Ų63.622%0.2234%0.344CS..  trans-87.5139.5175.2-57.5-177.7000109.4H244 L249 V253 Y263 D266 L270H244-L255 VanDerWaalsContact NE2-CD1 3.33Å; H244-L255 WeakPolarHBondContact NE2-CD1 3.26Å; L249-L255 HydrophobicContact CD1-CD1 4.06Å; L249-L255 HydrophobicContact CD2-CD1 3.84Å; L249-L255 HydrophobicContact CD2-CG 3.95Å; V253-L255 HydrophobicContact CG1-CD2 3.77Å; V253-L255 HydrophobicContact CG1-CG 4.19Å; L255-Y263 HydrophobicContact CB-CD2 4.15Å; L255-Y263 HydrophobicContact CB-CE2 3.91Å; L255-Y263 HydrophobicContact CD1-CE2 3.98Å; L255-D266 HydrophobicContact CD2-CB 3.67Å; L255-L270 HydrophobicContact CD2-CD2 4.42Å
256R95.6Very high91.5Very high120 Ų12062 Ų6245%0.45332%0.322SS..  trans-78.1-170.9176.2-69.9170.2-72.9177.2-2.8111.3E262 Y263 D266R256-E262 HydrophobicContact CB-CB 4.21Å; R256-E262 VanDerWaalsContact CZ-O 3.28Å; R256-E262 PolarHBondContact NE-O 2.72Å; R256-E262 PolarHBondContact NH2-O 2.87Å; R256-Y263 WeakPolarHBondContact O-CD2 3.41Å; R256-D266 VanDerWaalsContact CB-OD2 3.31Å; R256-D266 WeakPolarHBondContact CB-OD2 2.99Å; R256-D266 WeakPolarHBondContact CG-OD2 3.17Å; R256-D266 IonicContact CZ-OD1 3.99Å; R256-D266 VanDerWaalsContact CZ-OD1 3.22Å; R256-D266 IonicContact CZ-OD2 3.98Å; R256-D266 PolarHBondContact N-OD2 2.93Å; R256-D266 VanDerWaalsContact NE-CG 3.33Å; R256-D266 IonicContact NE-OD1 2.64Å; R256-D266 PolarHBondContact NE-OD1 3.47Å; R256-D266 VanDerWaalsContact NE-OD1 3.12Å; R256-D266 IonicContact NE-OD2 2.85Å; R256-D266 PolarHBondContact NE-OD2 3.18Å; R256-D266 IonicContact NH2-OD1 3.09Å; R256-D266 PolarHBondContact NH2-OD1 3.36Å; R256-D266 IonicContact NH2-OD2 3.98Å
257E94.9Very high91.6Very high141 Ų14158.6 Ų58.666%0.65931%0.307SS*.  trans-68.1132.1-174.9-171.9-176.6178.500112.4T260 Y263E257-T260 HydrophobicContact CB-CG2 4.06Å; E257-T260 HydrophobicContact CG-CG2 4.44Å; E257-T260 WeakPolarHBondContact O-CB 3.42Å; E257-T260 VanDerWaalsContact O-CG2 3.26Å; E257-T260 WeakPolarHBondContact O-CG2 3.38Å; E257-T260 PolarHBondContact O-OG1 3.46Å; E257-Y263 WeakPolarHBondContact O-CB 3.33Å
258C95.9Very high91.7Very high26 Ų2659.5 Ų59.518%0.17631%0.314CS..THydrogen-bonded Turntrans-62.2145.3175.5-62.10000111.5K237 M240 Y263 L296K237-C258 HydrophobicContact CG-CB 4.3Å; M240-C258 HydrophobicContact CE-CB 3.78Å; M240-C258 WeakPolarHBondContact CE-SG 3.38Å; M240-C258 HydrophobicContact SD-CB 3.97Å; C258-Y263 VanDerWaalsContact SG-CE2 3.57Å; C258-L296 HydrophobicContact CB-CD1 4Å
259G92.6Very high92.4Very high19 Ų1959.8 Ų59.820%0.19631%0.307CS..THydrogen-bonded Turntrans82.823.4-175.100000113.3N293 L297G259-N293 VanDerWaalsContact CA-OD1 3.28Å; G259-N293 WeakPolarHBondContact CA-OD1 3.44Å; G259-N293 PolarHBondContact N-OD1 3.15Å; G259-L297 VanDerWaalsContact O-CD2 3.29Å; G259-L297 WeakPolarHBondContact O-CD2 3.49Å
260T90.7Very high92.8Very high13 Ų1357.2 Ų57.28%0.0829%0.293CS..SBendtrans-126.4161.1-17971.80000111.8E257 E262 Y263 E264 N293E257-T260 HydrophobicContact CB-CG2 4.06Å; E257-T260 HydrophobicContact CG-CG2 4.44Å; E257-T260 WeakPolarHBondContact O-CB 3.42Å; E257-T260 VanDerWaalsContact O-CG2 3.26Å; E257-T260 WeakPolarHBondContact O-CG2 3.38Å; E257-T260 PolarHBondContact O-OG1 3.46Å; T260-E262 VanDerWaalsContact C-N 3.27Å; T260-E262 WeakPolarHBondContact CB-OE2 3.49Å; T260-Y263 WeakPolarHBondContact OG1-CB 3.33Å; T260-Y263 PolarHBondContact OG1-N 2.88Å; T260-E264 PolarHBondContact O-N 3.42Å; T260-N293 PolarHBondContact N-OD1 3.28Å; T260-N293 PolarHBondContact O-ND2 2.95Å; T260-N293 PolarHBondContact O-OD1 2.97Å
261Q88.2Confident93.3Very high65 Ų6557.4 Ų57.430%0.30429%0.292SS..Hα-helixtrans-72.1-31.6175-64.8-177.51100110.7E264 A265 R379Q261-E264 WeakPolarHBondContact O-CB 3.4Å; Q261-E264 PolarHBondContact O-N 3.06Å; Q261-A265 PolarHBondContact O-N 3.18Å; Q261-R379 VanDerWaalsContact NE2-CZ 3.32Å
262E92.4Very high93.7Very high75 Ų7554.9 Ų54.935%0.3527%0.271SS..Hα-helixtrans-59.7-46.8175.3-68.283.6176.600110.6R256 T260 A265 D266 R490R256-E262 HydrophobicContact CB-CB 4.21Å; R256-E262 VanDerWaalsContact CZ-O 3.28Å; R256-E262 PolarHBondContact NE-O 2.72Å; R256-E262 PolarHBondContact NH2-O 2.87Å; T260-E262 VanDerWaalsContact C-N 3.27Å; T260-E262 WeakPolarHBondContact CB-OE2 3.49Å; E262-A265 WeakPolarHBondContact O-CB 3.41Å; E262-A265 PolarHBondContact O-N 3.23Å; E262-D266 VanDerWaalsContact O-CG 3.28Å; E262-D266 PolarHBondContact O-N 3.22Å; E262-R490 IonicContact OE1-NH1 3.46Å; E262-R490 IonicContact OE2-NH1 3.55Å; E262-R490 PolarHBondContact OE2-NH1 3Å
263Y95.8Very high93.9Very high0 Ų052.6 Ų52.60%025%0.254CS..Hα-helixtrans-66.3-39.9173.5-176.4-87.7000112.8M240 H244 L255 R256 E257 C258 T260 A265 D266 V267 L289 N293M240-Y263 HydrophobicContact CE-CD1 4.12Å; M240-Y263 HydrophobicContact CE-CE1 3.25Å; M240-Y263 HydrophobicContact CE-CE2 4.45Å; M240-Y263 VanDerWaalsContact CE-CZ 3.44Å; M240-Y263 VanDerWaalsContact CE-OH 3.28Å; M240-Y263 WeakPolarHBondContact CE-OH 3.36Å; H244-Y263 PolarHBondContact CE1-OH 2.92Å; H244-Y263 VanDerWaalsContact CE1-OH 3.23Å; H244-Y263 AromaticContact NE2-CZ 3.9Å; H244-Y263 PolarHBondContact NE2-OH 2.87Å; L255-Y263 HydrophobicContact CB-CD2 4.15Å; L255-Y263 HydrophobicContact CB-CE2 3.91Å; L255-Y263 HydrophobicContact CD1-CE2 3.98Å; R256-Y263 WeakPolarHBondContact O-CD2 3.41Å; E257-Y263 WeakPolarHBondContact O-CB 3.33Å; C258-Y263 VanDerWaalsContact SG-CE2 3.57Å; T260-Y263 WeakPolarHBondContact OG1-CB 3.33Å; T260-Y263 PolarHBondContact OG1-N 2.88Å; Y263-A265 PolarHBondContact O-N 2.84Å; Y263-D266 WeakPolarHBondContact O-CB 2.95Å; Y263-D266 PolarHBondContact O-N 2.86Å; Y263-V267 HydrophobicContact CD1-CG1 3.91Å; Y263-V267 HydrophobicContact CD1-CG2 4.47Å; Y263-V267 HydrophobicContact CE1-CG1 3.37Å; Y263-V267 HydrophobicContact CE1-CG2 4.4Å; Y263-V267 HydrophobicContact CE2-CG1 4.26Å; Y263-V267 WeakPolarHBondContact O-CG2 3.44Å; Y263-V267 PolarHBondContact O-N 3.02Å; Y263-L289 HydrophobicContact CE1-CB 4.39Å; Y263-L289 WeakPolarHBondContact OH-CD2 3.48Å; Y263-N293 HydrophobicContact CD1-CB 3.81Å; Y263-N293 VanDerWaalsContact CD1-OD1 3.27Å; Y263-N293 WeakPolarHBondContact CD1-OD1 3.48Å; Y263-N293 HydrophobicContact CE1-CB 4.05Å
264E95.3Very high94.2Very high41 Ų4151.4 Ų51.419%0.19225%0.247CC..Hα-helixtrans-53.8-45.4173.3-166.3-166.2154.600110.7T260 Q261 V267 V268 R290T260-E264 PolarHBondContact O-N 3.42Å; Q261-E264 WeakPolarHBondContact O-CB 3.4Å; Q261-E264 PolarHBondContact O-N 3.06Å; E264-V267 WeakPolarHBondContact O-CG2 3.4Å; E264-V268 WeakPolarHBondContact O-CB 3.46Å; E264-V268 VanDerWaalsContact O-CG2 3.24Å; E264-V268 WeakPolarHBondContact O-CG2 3.23Å; E264-V268 PolarHBondContact O-N 3.28Å; E264-R290 HydrophobicContact CG-CG 4.23Å; E264-R290 IonicContact OE1-CZ 3.4Å; E264-R290 IonicContact OE1-NE 3.53Å; E264-R290 IonicContact OE1-NH2 2.72Å; E264-R290 PolarHBondContact OE1-NH2 3.48Å; E264-R290 VanDerWaalsContact OE1-NH2 3.16Å
265A94.7Very high94.3Very high43 Ų4342.5 Ų42.536%0.35521%0.213SC..Hα-helixtrans-63.7-41.3176.600000112.2Q261 E262 Y263 V268 I269Q261-A265 PolarHBondContact O-N 3.18Å; E262-A265 WeakPolarHBondContact O-CB 3.41Å; E262-A265 PolarHBondContact O-N 3.23Å; Y263-A265 PolarHBondContact O-N 2.84Å; A265-V268 PolarHBondContact O-N 3.26Å; A265-I269 VanDerWaalsContact O-CG1 3.31Å; A265-I269 WeakPolarHBondContact O-CG1 3.31Å; A265-I269 PolarHBondContact O-N 3.28Å
266D96.3Very high94.3Very high23 Ų2342.9 Ų42.912%0.12322%0.22CC..Hα-helixtrans-61.9-47.4178.9-65.1-25.5000111.6L255 R256 E262 Y263 V268 I269 L270L255-D266 HydrophobicContact CD2-CB 3.67Å; R256-D266 VanDerWaalsContact CB-OD2 3.31Å; R256-D266 WeakPolarHBondContact CB-OD2 2.99Å; R256-D266 WeakPolarHBondContact CG-OD2 3.17Å; R256-D266 IonicContact CZ-OD1 3.99Å; R256-D266 VanDerWaalsContact CZ-OD1 3.22Å; R256-D266 IonicContact CZ-OD2 3.98Å; R256-D266 PolarHBondContact N-OD2 2.93Å; R256-D266 VanDerWaalsContact NE-CG 3.33Å; R256-D266 IonicContact NE-OD1 2.64Å; R256-D266 PolarHBondContact NE-OD1 3.47Å; R256-D266 VanDerWaalsContact NE-OD1 3.12Å; R256-D266 IonicContact NE-OD2 2.85Å; R256-D266 PolarHBondContact NE-OD2 3.18Å; R256-D266 IonicContact NH2-OD1 3.09Å; R256-D266 PolarHBondContact NH2-OD1 3.36Å; R256-D266 IonicContact NH2-OD2 3.98Å; E262-D266 VanDerWaalsContact O-CG 3.28Å; E262-D266 PolarHBondContact O-N 3.22Å; Y263-D266 WeakPolarHBondContact O-CB 2.95Å; Y263-D266 PolarHBondContact O-N 2.86Å; D266-V268 VanDerWaalsContact C-N 3.34Å; D266-V268 PolarHBondContact O-N 2.82Å; D266-I269 PolarHBondContact O-N 2.76Å; D266-L270 WeakPolarHBondContact O-CB 3.49Å; D266-L270 PolarHBondContact O-N 3.48Å
267V96.8Very high94.3Very high1 Ų142.3 Ų42.31%0.00622%0.222CC..Hα-helixtrans-71.5-28.3-179.6-60.40000112.6Y263 E264 L270 E271 L289 R290Y263-V267 HydrophobicContact CD1-CG1 3.91Å; Y263-V267 HydrophobicContact CD1-CG2 4.47Å; Y263-V267 HydrophobicContact CE1-CG1 3.37Å; Y263-V267 HydrophobicContact CE1-CG2 4.4Å; Y263-V267 HydrophobicContact CE2-CG1 4.26Å; Y263-V267 WeakPolarHBondContact O-CG2 3.44Å; Y263-V267 PolarHBondContact O-N 3.02Å; E264-V267 WeakPolarHBondContact O-CG2 3.4Å; V267-L270 PolarHBondContact O-N 3.33Å; V267-E271 WeakPolarHBondContact O-CB 3.32Å; V267-E271 PolarHBondContact O-N 2.96Å; V267-L289 HydrophobicContact CG1-CB 4Å; V267-L289 HydrophobicContact CG1-CD1 4.35Å; V267-R290 HydrophobicContact CG2-CB 3.72Å; V267-R290 HydrophobicContact CG2-CG 4.2Å
268V95.1Very high94.2Very high31 Ų3139.9 Ų39.919%0.18821%0.214CC..Hα-helixtrans-66.7-39.5170.91680000111.4E264 A265 D266 Q272E264-V268 WeakPolarHBondContact O-CB 3.46Å; E264-V268 VanDerWaalsContact O-CG2 3.24Å; E264-V268 WeakPolarHBondContact O-CG2 3.23Å; E264-V268 PolarHBondContact O-N 3.28Å; A265-V268 PolarHBondContact O-N 3.26Å; D266-V268 VanDerWaalsContact C-N 3.34Å; D266-V268 PolarHBondContact O-N 2.82Å; V268-Q272 VanDerWaalsContact O-CG 3.31Å; V268-Q272 WeakPolarHBondContact O-CG 3.25Å; V268-Q272 PolarHBondContact O-N 3.3Å
269I94.8Very high94.1Very high105 Ų10541.7 Ų41.754%0.53822%0.221SC..Hα-helixtrans-68.1-40.5174.6-67.6164.6000110A265 D266 E271 Q272 R273A265-I269 VanDerWaalsContact O-CG1 3.31Å; A265-I269 WeakPolarHBondContact O-CG1 3.31Å; A265-I269 PolarHBondContact O-N 3.28Å; D266-I269 PolarHBondContact O-N 2.76Å; I269-E271 VanDerWaalsContact C-N 3.35Å; I269-E271 PolarHBondContact O-N 3.09Å; I269-Q272 PolarHBondContact O-N 3.02Å; I269-R273 PolarHBondContact O-N 2.86Å
270L95.6Very high94.2Very high4 Ų442 Ų422%0.02122%0.217CC..Hα-helixtrans-62.8-41.1178-166.863.9000112M247 L249 V253 L255 D266 V267 R273 G274 L282 A286M247-L270 HydrophobicContact CE-CD2 4.23Å; M247-L270 HydrophobicContact SD-CD2 3.99Å; L249-L270 HydrophobicContact CD2-CD2 4.35Å; V253-L270 HydrophobicContact CG1-CD1 4.19Å; V253-L270 HydrophobicContact CG2-CD1 4.13Å; L255-L270 HydrophobicContact CD2-CD2 4.42Å; D266-L270 WeakPolarHBondContact O-CB 3.49Å; D266-L270 PolarHBondContact O-N 3.48Å; V267-L270 PolarHBondContact O-N 3.33Å; L270-R273 WeakPolarHBondContact O-CB 3.39Å; L270-R273 PolarHBondContact O-N 2.87Å; L270-G274 PolarHBondContact O-N 3.1Å; L270-L282 HydrophobicContact CD1-CD1 3.85Å; L270-L282 HydrophobicContact CD1-CD2 4.06Å; L270-L282 HydrophobicContact CD1-CG 4.21Å; L270-L282 HydrophobicContact CD2-CD1 3.97Å; L270-L282 HydrophobicContact CG-CD1 3.79Å; L270-L282 HydrophobicContact CG-CD2 4.47Å; L270-L282 HydrophobicContact CG-CG 4.11Å; L270-A286 HydrophobicContact CB-CB 4.06Å; L270-A286 HydrophobicContact CD2-CB 4.18Å; L270-A286 HydrophobicContact CG-CB 4.15Å
271E95.4Very high94.4Very high24 Ų2444 Ų4411%0.11223%0.227CC..Hα-helixtrans-62-45.6174-179.6-86.5167.600111.1V267 I269 R273 G274 V275 A283 A286 R559V267-E271 WeakPolarHBondContact O-CB 3.32Å; V267-E271 PolarHBondContact O-N 2.96Å; I269-E271 VanDerWaalsContact C-N 3.35Å; I269-E271 PolarHBondContact O-N 3.09Å; E271-R273 VanDerWaalsContact C-N 3.29Å; E271-R273 PolarHBondContact O-N 3.35Å; E271-G274 PolarHBondContact O-N 3.24Å; E271-G274 VanDerWaalsContact O-N 3.16Å; E271-V275 WeakPolarHBondContact O-CG2 3.41Å; E271-V275 PolarHBondContact O-N 3.17Å; E271-V275 WeakPolarHBondContact OE1-CG2 3.42Å; E271-A283 HydrophobicContact CG-CB 4.44Å; E271-A286 HydrophobicContact CB-CB 3.77Å; E271-R559 VanDerWaalsContact CD-NH2 3.28Å; E271-R559 IonicContact OE1-CZ 3.64Å; E271-R559 VanDerWaalsContact OE1-CZ 3.32Å; E271-R559 IonicContact OE1-NE 3.99Å; E271-R559 PolarHBondContact OE1-NE 2.96Å; E271-R559 IonicContact OE1-NH2 2.73Å; E271-R559 PolarHBondContact OE1-NH2 3Å; E271-R559 IonicContact OE2-CZ 2.79Å; E271-R559 IonicContact OE2-NE 2.79Å; E271-R559 IonicContact OE2-NH2 3.86Å; E271-R559 PolarHBondContact OE2-NH2 3.31Å
272Q94.3Very high94.8Very high58 Ų5841 Ų4127%0.27121%0.213SC..Hα-helixtrans-60.8-39.5176.8-71.2169.120.700112V268 I269 V275 S276V268-Q272 VanDerWaalsContact O-CG 3.31Å; V268-Q272 WeakPolarHBondContact O-CG 3.25Å; V268-Q272 PolarHBondContact O-N 3.3Å; I269-Q272 PolarHBondContact O-N 3.02Å; Q272-V275 PolarHBondContact O-N 2.84Å; Q272-S276 PolarHBondContact O-N 3.25Å; Q272-S276 PolarHBondContact O-OG 2.85Å
273R94.2Very high94.9Very high61 Ų6137.6 Ų37.623%0.2320%0.197CC..Hα-helixtrans-62-48.9173.6178.6175175.2166.5-2.7110.9D252 V253 I269 L270 E271 V275 S276 Q277 L282D252-R273 IonicContact OD1-CZ 2.66Å; D252-R273 IonicContact OD1-NH1 3.23Å; D252-R273 PolarHBondContact OD1-NH1 3.36Å; D252-R273 IonicContact OD1-NH2 3.49Å; D252-R273 PolarHBondContact OD1-NH2 2.93Å; D252-R273 IonicContact OD2-CZ 2.82Å; D252-R273 IonicContact OD2-NH1 3.78Å; D252-R273 PolarHBondContact OD2-NH1 3.1Å; D252-R273 IonicContact OD2-NH2 3.15Å; D252-R273 PolarHBondContact OD2-NH2 3.34Å; V253-R273 VanDerWaalsContact CG2-NH1 3.27Å; I269-R273 PolarHBondContact O-N 2.86Å; L270-R273 WeakPolarHBondContact O-CB 3.39Å; L270-R273 PolarHBondContact O-N 2.87Å; E271-R273 VanDerWaalsContact C-N 3.29Å; E271-R273 PolarHBondContact O-N 3.35Å; R273-V275 VanDerWaalsContact C-N 3.27Å; R273-V275 PolarHBondContact O-N 2.71Å; R273-S276 WeakPolarHBondContact CA-OG 3.46Å; R273-S276 PolarHBondContact O-N 2.94Å; R273-S276 VanDerWaalsContact O-N 3.11Å; R273-S276 PolarHBondContact O-OG 2.56Å; R273-Q277 HydrophobicContact CG-CG 4.28Å; R273-Q277 WeakPolarHBondContact O-CB 3.39Å; R273-Q277 WeakPolarHBondContact O-CG 3.22Å; R273-Q277 PolarHBondContact O-N 3.13Å; R273-L282 HydrophobicContact CG-CD2 4.45Å
274G94.8Very high94.9Very high0 Ų037.9 Ų37.90%020%0.199CC..Hα-helixtrans-54.3-45.1175.700000112L270 E271 Q277 D278 N279L270-G274 PolarHBondContact O-N 3.1Å; E271-G274 PolarHBondContact O-N 3.24Å; E271-G274 VanDerWaalsContact O-N 3.16Å; G274-Q277 PolarHBondContact O-N 3.17Å; G274-D278 PolarHBondContact O-N 2.9Å; G274-N279 CarbonylContact C-O 3.54Å; G274-N279 CarbonylContact O-C 3.55Å; G274-N279 PolarHBondContact O-N 3.09Å
275V94.2Very high95Very high0 Ų036 Ų360%019%0.19CC..Hα-helixtrans-61-50.8174.2178.40000111.6E271 Q272 R273 Q277 D278 A283 R559 F562 A643 R650 T652E271-V275 WeakPolarHBondContact O-CG2 3.41Å; E271-V275 PolarHBondContact O-N 3.17Å; E271-V275 WeakPolarHBondContact OE1-CG2 3.42Å; Q272-V275 PolarHBondContact O-N 2.84Å; R273-V275 VanDerWaalsContact C-N 3.27Å; R273-V275 PolarHBondContact O-N 2.71Å; V275-Q277 PolarHBondContact O-N 2.97Å; V275-D278 PolarHBondContact O-N 3.44Å; V275-A283 HydrophobicContact CG2-CB 4.13Å; V275-R559 HydrophobicContact CG2-CG 4.12Å; V275-F562 HydrophobicContact CB-CE1 4.27Å; V275-F562 HydrophobicContact CB-CZ 4.37Å; V275-F562 HydrophobicContact CG1-CE1 3.99Å; V275-F562 HydrophobicContact CG2-CE1 4.01Å; V275-F562 HydrophobicContact CG2-CZ 4.17Å; V275-A643 HydrophobicContact CG1-CB 3.47Å; V275-A643 VanDerWaalsContact CG1-CB 3.47Å; V275-R650 WeakPolarHBondContact O-CD 3.28Å; V275-T652 HydrophobicContact CB-CG2 3.89Å; V275-T652 HydrophobicContact CG1-CG2 3.39Å; V275-T652 HydrophobicContact CG2-CG2 4.43Å
276S93.6Very high95.1Very high51 Ų5134 Ų3436%0.35717%0.173SC..Hα-helixtrans-62.7-27.1-178.264.80000114.7Q272 R273 R650Q272-S276 PolarHBondContact O-N 3.25Å; Q272-S276 PolarHBondContact O-OG 2.85Å; R273-S276 WeakPolarHBondContact CA-OG 3.46Å; R273-S276 PolarHBondContact O-N 2.94Å; R273-S276 VanDerWaalsContact O-N 3.11Å; R273-S276 PolarHBondContact O-OG 2.56Å; S276-R650 WeakPolarHBondContact CA-O 3.45Å; S276-R650 VanDerWaalsContact CB-O 3.26Å; S276-R650 WeakPolarHBondContact CB-O 3.34Å
277Q93.9Very high95.1Very high107 Ų10735.1 Ų35.150%0.518%0.179SC..THydrogen-bonded Turntrans-97.39-177.9-66.8-176.2-27.800112.9R273 G274 V275 N279R273-Q277 HydrophobicContact CG-CG 4.28Å; R273-Q277 WeakPolarHBondContact O-CB 3.39Å; R273-Q277 WeakPolarHBondContact O-CG 3.22Å; R273-Q277 PolarHBondContact O-N 3.13Å; G274-Q277 PolarHBondContact O-N 3.17Å; V275-Q277 PolarHBondContact O-N 2.97Å; Q277-N279 HydrophobicContact CB-CB 4.36Å; Q277-N279 PolarHBondContact O-N 2.94Å; Q277-N279 VanDerWaalsContact O-N 3.15Å
278D93.5Very high95.1Very high91 Ų9135.3 Ų35.349%0.48718%0.18SC..THydrogen-bonded Turntrans54.629.5-172.8-153.58.7000113.6G274 V275 F562 R650G274-D278 PolarHBondContact O-N 2.9Å; V275-D278 PolarHBondContact O-N 3.44Å; D278-F562 WeakPolarHBondContact OD1-CD2 3.39Å; D278-R650 IonicContact OD1-CZ 3.67Å; D278-R650 IonicContact OD1-NH1 2.61Å; D278-R650 PolarHBondContact OD1-NH1 2.87Å; D278-R650 IonicContact OD1-NH2 2.94Å; D278-R650 PolarHBondContact OD1-NH2 3.49Å; D278-R650 IonicContact OD2-CZ 3.23Å; D278-R650 IonicContact OD2-NH1 2.68Å; D278-R650 IonicContact OD2-NH2 3.32Å; D278-R650 PolarHBondContact OD2-NH2 3.26Å
279N94.4Very high95.2Very high63 Ų6333.8 Ų33.834%0.33717%0.171SC..  trans-102.587-178.2-173.2-20.7000109.6G274 Q277 L281 L282 A283G274-N279 CarbonylContact C-O 3.54Å; G274-N279 CarbonylContact O-C 3.55Å; G274-N279 PolarHBondContact O-N 3.09Å; Q277-N279 HydrophobicContact CB-CB 4.36Å; Q277-N279 PolarHBondContact O-N 2.94Å; Q277-N279 VanDerWaalsContact O-N 3.15Å; N279-L281 VanDerWaalsContact C-N 3.29Å; N279-L281 PolarHBondContact O-N 3.29Å; N279-L281 PolarHBondContact OD1-N 3.27Å; N279-L282 HydrophobicContact CB-CB 4.14Å; N279-L282 PolarHBondContact O-N 3.37Å; N279-L282 WeakPolarHBondContact OD1-CB 3.31Å; N279-L282 PolarHBondContact OD1-N 3.49Å; N279-A283 PolarHBondContact O-N 3.19Å; N279-A283 VanDerWaalsContact O-N 3.11Å
280R94.1Very high95.3Very high26 Ų2633.3 Ų33.310%0.09816%0.162CC..Hα-helixtrans-61.6-40-178.3-174.3-179.9-179.8-78.6-5.4111.5L282 A283 Q284 D324 D327 N560 F562R280-L282 VanDerWaalsContact C-N 3.35Å; R280-L282 PolarHBondContact O-N 2.78Å; R280-A283 PolarHBondContact O-N 3.44Å; R280-Q284 HydrophobicContact CG-CG 4Å; R280-Q284 WeakPolarHBondContact O-CG 3.38Å; R280-Q284 PolarHBondContact O-N 3.09Å; R280-D324 WeakPolarHBondContact CD-OD2 3.25Å; R280-D324 IonicContact CZ-OD2 3.64Å; R280-D324 IonicContact NE-OD2 2.96Å; R280-D324 IonicContact NH1-OD1 3.22Å; R280-D324 PolarHBondContact NH1-OD1 3.09Å; R280-D324 IonicContact NH1-OD2 2.63Å; R280-D324 PolarHBondContact NH1-OD2 3.23Å; R280-D327 IonicContact CZ-OD1 3.81Å; R280-D327 IonicContact CZ-OD2 3.61Å; R280-D327 IonicContact NH1-OD1 3.64Å; R280-D327 PolarHBondContact NH1-OD1 3.4Å; R280-D327 IonicContact NH1-OD2 3.18Å; R280-D327 PolarHBondContact NH1-OD2 3.09Å; R280-D327 VanDerWaalsContact NH2-CG 3.28Å; R280-D327 IonicContact NH2-OD1 2.97Å; R280-D327 PolarHBondContact NH2-OD1 3Å; R280-D327 IonicContact NH2-OD2 2.77Å; R280-D327 PolarHBondContact NH2-OD2 3.49Å; R280-N560 PolarHBondContact NE-O 2.97Å; R280-F562 HydrophobicContact CB-CD2 4.18Å; R280-F562 HydrophobicContact CB-CE2 3.73Å; R280-F562 HydrophobicContact CB-CZ 4.47Å; R280-F562 HydrophobicContact CG-CE2 4.44Å
281L95.8Very high95.4Very high55 Ų5534.6 Ų34.629%0.28817%0.168SC..Hα-helixtrans-56.1-51.2179.2-173.1159.4000110.5F246 M247 N279 A283 Q284 C285 T326F246-L281 HydrophobicContact CD1-CD2 4.37Å; F246-L281 HydrophobicContact CE1-CD1 3.95Å; F246-L281 HydrophobicContact CE1-CD2 4.19Å; F246-L281 HydrophobicContact CE1-CG 3.95Å; F246-L281 HydrophobicContact CZ-CD1 4.27Å; M247-L281 HydrophobicContact CB-CD2 4.01Å; N279-L281 VanDerWaalsContact C-N 3.29Å; N279-L281 PolarHBondContact O-N 3.29Å; N279-L281 PolarHBondContact OD1-N 3.27Å; L281-A283 PolarHBondContact O-N 2.94Å; L281-Q284 PolarHBondContact O-N 2.79Å; L281-C285 WeakPolarHBondContact O-CB 3.01Å; L281-C285 PolarHBondContact O-N 3.41Å; L281-C285 PolarHBondContact O-SG 3.14Å; L281-T326 HydrophobicContact CG-CG2 4.23Å
282L95.8Very high95.5Very high3 Ų333.4 Ų33.42%0.01616%0.163CC..Hα-helixtrans-61.5-43.6178.1-173.263.4000111.8M247 P250 L270 R273 N279 R280 A286M247-L282 HydrophobicContact CE-CD1 4.47Å; M247-L282 HydrophobicContact SD-CD1 4.13Å; P250-L282 HydrophobicContact CG-CD2 4.42Å; L270-L282 HydrophobicContact CD1-CD1 3.85Å; L270-L282 HydrophobicContact CD1-CD2 4.06Å; L270-L282 HydrophobicContact CD1-CG 4.21Å; L270-L282 HydrophobicContact CD2-CD1 3.97Å; L270-L282 HydrophobicContact CG-CD1 3.79Å; L270-L282 HydrophobicContact CG-CD2 4.47Å; L270-L282 HydrophobicContact CG-CG 4.11Å; R273-L282 HydrophobicContact CG-CD2 4.45Å; N279-L282 HydrophobicContact CB-CB 4.14Å; N279-L282 PolarHBondContact O-N 3.37Å; N279-L282 WeakPolarHBondContact OD1-CB 3.31Å; N279-L282 PolarHBondContact OD1-N 3.49Å; R280-L282 VanDerWaalsContact C-N 3.35Å; R280-L282 PolarHBondContact O-N 2.78Å; L282-A286 WeakPolarHBondContact O-CB 3.36Å; L282-A286 PolarHBondContact O-N 3.01Å
283A95.1Very high95.6Very high3 Ų330.7 Ų30.73%0.02515%0.15CC..Hα-helixtrans-63.1-45.4-179.700000112.6E271 V275 N279 R280 L281 L287 F562E271-A283 HydrophobicContact CG-CB 4.44Å; V275-A283 HydrophobicContact CG2-CB 4.13Å; N279-A283 PolarHBondContact O-N 3.19Å; N279-A283 VanDerWaalsContact O-N 3.11Å; R280-A283 PolarHBondContact O-N 3.44Å; L281-A283 PolarHBondContact O-N 2.94Å; A283-L287 WeakPolarHBondContact O-CB 3.27Å; A283-L287 PolarHBondContact O-N 2.93Å; A283-F562 HydrophobicContact CB-CZ 4.32Å
284Q95.4Very high95.6Very high6 Ų629.8 Ų29.83%0.02815%0.149CC..Hα-helixtrans-70.1-44.9179.9-66.4-55.6-36.300111.8R280 L281 A286 L287 H288 T326 L330 N560R280-Q284 HydrophobicContact CG-CG 4Å; R280-Q284 WeakPolarHBondContact O-CG 3.38Å; R280-Q284 PolarHBondContact O-N 3.09Å; L281-Q284 PolarHBondContact O-N 2.79Å; Q284-A286 VanDerWaalsContact C-N 3.31Å; Q284-A286 PolarHBondContact O-N 2.92Å; Q284-L287 WeakPolarHBondContact O-CB 3.21Å; Q284-L287 PolarHBondContact O-N 2.96Å; Q284-L287 VanDerWaalsContact O-N 3.16Å; Q284-H288 PolarHBondContact O-CD2 2.96Å; Q284-H288 PolarHBondContact O-N 3.19Å; Q284-T326 HydrophobicContact CB-CG2 3.99Å; Q284-L330 HydrophobicContact CB-CD1 4.16Å; Q284-N560 PolarHBondContact NE2-O 3.43Å; Q284-N560 PolarHBondContact NE2-OD1 3.28Å
285C97.3Very high95.6Very high0 Ų029.8 Ų29.80%015%0.149CC..Hα-helixtrans-60.2-42.4176.4-69.50000111.5I243 M247 L281 L287 H288 L289I243-C285 HydrophobicContact CG2-CB 3.76Å; M247-C285 HydrophobicContact CB-CB 4.13Å; M247-C285 HydrophobicContact CE-CB 3.22Å; L281-C285 WeakPolarHBondContact O-CB 3.01Å; L281-C285 PolarHBondContact O-N 3.41Å; L281-C285 PolarHBondContact O-SG 3.14Å; C285-L287 PolarHBondContact O-N 3.49Å; C285-H288 PolarHBondContact O-N 2.81Å; C285-L289 WeakPolarHBondContact O-CB 3.49Å; C285-L289 VanDerWaalsContact O-CG 3.25Å; C285-L289 WeakPolarHBondContact O-CG 3.18Å; C285-L289 PolarHBondContact O-N 3.39Å
286A97.1Very high95.7Very high1 Ų130.3 Ų30.31%0.00815%0.152CC..Hα-helixtrans-63.3-39.4175.400000112.9L270 E271 L282 Q284 R290L270-A286 HydrophobicContact CB-CB 4.06Å; L270-A286 HydrophobicContact CD2-CB 4.18Å; L270-A286 HydrophobicContact CG-CB 4.15Å; E271-A286 HydrophobicContact CB-CB 3.77Å; L282-A286 WeakPolarHBondContact O-CB 3.36Å; L282-A286 PolarHBondContact O-N 3.01Å; Q284-A286 VanDerWaalsContact C-N 3.31Å; Q284-A286 PolarHBondContact O-N 2.92Å; A286-R290 PolarHBondContact O-N 3.34Å
287L95.3Very high95.6Very high48 Ų4829.3 Ų29.325%0.25114%0.143SC..Hα-helixtrans-61-44173.7179.168000112A283 Q284 C285 R290 Q291A283-L287 WeakPolarHBondContact O-CB 3.27Å; A283-L287 PolarHBondContact O-N 2.93Å; Q284-L287 WeakPolarHBondContact O-CB 3.21Å; Q284-L287 PolarHBondContact O-N 2.96Å; Q284-L287 VanDerWaalsContact O-N 3.16Å; C285-L287 PolarHBondContact O-N 3.49Å; L287-R290 WeakPolarHBondContact O-CB 3.44Å; L287-R290 PolarHBondContact O-N 3.35Å; L287-Q291 PolarHBondContact O-N 3.31Å
288H96.8Very high95.5Very high4 Ų425 Ų252%0.01912%0.123CC..Hα-helixtrans-71.6-40.2179.5-77.4-122000111.9Q284 C285 R290 Q291 Y292 F314 Y315 L330Q284-H288 PolarHBondContact O-CD2 2.96Å; Q284-H288 PolarHBondContact O-N 3.19Å; C285-H288 PolarHBondContact O-N 2.81Å; H288-R290 PolarHBondContact O-N 3.38Å; H288-Q291 WeakPolarHBondContact O-CB 3.29Å; H288-Q291 PolarHBondContact O-N 3.29Å; H288-Y292 VanDerWaalsContact O-CD2 3.22Å; H288-Y292 WeakPolarHBondContact O-CD2 3.26Å; H288-Y292 PolarHBondContact O-N 3.4Å; H288-F314 AromaticContact CE1-CE1 3.67Å; H288-F314 AromaticContact ND1-CE1 3.73Å; H288-F314 AromaticContact NE2-CE1 3.94Å; H288-F314 AromaticContact NE2-CZ 3.92Å; H288-Y315 AromaticContact CE1-CE1 3.62Å; H288-Y315 AromaticContact ND1-CE1 3.49Å; H288-Y315 WeakPolarHBondContact ND1-CE1 3.27Å; H288-Y315 AromaticContact ND1-CZ 3.49Å; H288-Y315 PolarHBondContact ND1-OH 2.95Å; H288-L330 HydrophobicContact CB-CD1 4.3Å; H288-L330 HydrophobicContact CB-CD2 4.09Å
289L98.1Very high95.5Very high0 Ų020.7 Ų20.70%010%0.1CC..Hα-helixtrans-58-37.3172.8-74.9171.9000112.1M240 I243 H244 M247 Y263 V267 C285 Q291 Y292 N293M240-L289 HydrophobicContact CB-CD2 3.8Å; M240-L289 HydrophobicContact CE-CD2 4.23Å; M240-L289 HydrophobicContact CG-CD2 3.98Å; I243-L289 HydrophobicContact CB-CD2 3.89Å; I243-L289 HydrophobicContact CB-CG 4.35Å; I243-L289 HydrophobicContact CD1-CD2 4.2Å; I243-L289 HydrophobicContact CG2-CD1 4.16Å; I243-L289 HydrophobicContact CG2-CD2 3.9Å; I243-L289 HydrophobicContact CG2-CG 3.78Å; H244-L289 WeakPolarHBondContact NE2-CD1 3.38Å; M247-L289 HydrophobicContact CE-CD1 3.47Å; M247-L289 VanDerWaalsContact CE-CD1 3.47Å; M247-L289 HydrophobicContact SD-CD1 4.43Å; Y263-L289 HydrophobicContact CE1-CB 4.39Å; Y263-L289 WeakPolarHBondContact OH-CD2 3.48Å; V267-L289 HydrophobicContact CG1-CB 4Å; V267-L289 HydrophobicContact CG1-CD1 4.35Å; C285-L289 WeakPolarHBondContact O-CB 3.49Å; C285-L289 VanDerWaalsContact O-CG 3.25Å; C285-L289 WeakPolarHBondContact O-CG 3.18Å; C285-L289 PolarHBondContact O-N 3.39Å; L289-Q291 VanDerWaalsContact C-N 3.34Å; L289-Y292 PolarHBondContact O-N 3.01Å; L289-N293 WeakPolarHBondContact O-CB 3.49Å; L289-N293 PolarHBondContact O-N 3.02Å
290R97.3Very high95.2Very high95 Ų9520.9 Ų20.936%0.35810%0.101SC..Hα-helixtrans-59.9-45.4172.1-172.7-172.2176-179.24.1111.4E264 V267 A286 L287 H288 Y292 N293 D294E264-R290 HydrophobicContact CG-CG 4.23Å; E264-R290 IonicContact OE1-CZ 3.4Å; E264-R290 IonicContact OE1-NE 3.53Å; E264-R290 IonicContact OE1-NH2 2.72Å; E264-R290 PolarHBondContact OE1-NH2 3.48Å; E264-R290 VanDerWaalsContact OE1-NH2 3.16Å; V267-R290 HydrophobicContact CG2-CB 3.72Å; V267-R290 HydrophobicContact CG2-CG 4.2Å; A286-R290 PolarHBondContact O-N 3.34Å; L287-R290 WeakPolarHBondContact O-CB 3.44Å; L287-R290 PolarHBondContact O-N 3.35Å; H288-R290 PolarHBondContact O-N 3.38Å; R290-Y292 PolarHBondContact O-N 3.31Å; R290-N293 WeakPolarHBondContact O-CB 3.29Å; R290-N293 PolarHBondContact O-N 3.16Å; R290-D294 PolarHBondContact O-N 2.85Å
291Q96.3Very high94.9Very high30 Ų3020.9 Ų20.914%0.1410%0.104CC..Hα-helixtrans-63.7-40.7179.3-172.467.116.100112.3L287 H288 L289 D294 A295 S310 L311 F314L287-Q291 PolarHBondContact O-N 3.31Å; H288-Q291 WeakPolarHBondContact O-CB 3.29Å; H288-Q291 PolarHBondContact O-N 3.29Å; L289-Q291 VanDerWaalsContact C-N 3.34Å; Q291-D294 PolarHBondContact O-N 3.42Å; Q291-A295 PolarHBondContact O-N 3.19Å; Q291-S310 PolarHBondContact NE2-O 3.01Å; Q291-S310 PolarHBondContact NE2-OG 3.17Å; Q291-L311 HydrophobicContact CG-CD2 3.84Å; Q291-F314 HydrophobicContact CB-CD1 4.34Å; Q291-F314 HydrophobicContact CB-CE1 4.31Å; Q291-F314 HydrophobicContact CB-CE2 4.48Å; Q291-F314 HydrophobicContact CB-CG 4.43Å; Q291-F314 HydrophobicContact CB-CZ 4.38Å; Q291-F314 HydrophobicContact CG-CB 3.92Å; Q291-F314 HydrophobicContact CG-CD1 3.79Å; Q291-F314 HydrophobicContact CG-CD2 3.96Å; Q291-F314 HydrophobicContact CG-CE1 4.25Å; Q291-F314 HydrophobicContact CG-CE2 4.41Å; Q291-F314 HydrophobicContact CG-CG 3.62Å
292Y98Very high94.7Very high0 Ų018.3 Ų18.30%09%0.09CC..Hα-helixtrans-64.8-39.5172.9-75.5-71.1000112.3I236 M239 M240 I243 H288 L289 R290 A295 L296 L311 Y315I236-Y292 HydrophobicContact CG2-CD1 3.87Å; I236-Y292 HydrophobicContact CG2-CG 4.35Å; M239-Y292 HydrophobicContact CB-CE1 4.45Å; M239-Y292 HydrophobicContact CE-CE1 3.82Å; M239-Y292 WeakPolarHBondContact CE-OH 3.46Å; M239-Y292 HydrophobicContact SD-CE1 3.99Å; M240-Y292 HydrophobicContact CG-CG 4.1Å; I243-Y292 HydrophobicContact CD1-CD2 3.8Å; I243-Y292 HydrophobicContact CD1-CE2 3.51Å; H288-Y292 VanDerWaalsContact O-CD2 3.22Å; H288-Y292 WeakPolarHBondContact O-CD2 3.26Å; H288-Y292 PolarHBondContact O-N 3.4Å; L289-Y292 PolarHBondContact O-N 3.01Å; R290-Y292 PolarHBondContact O-N 3.31Å; Y292-A295 WeakPolarHBondContact O-CB 3.42Å; Y292-A295 PolarHBondContact O-N 2.69Å; Y292-L296 PolarHBondContact O-N 3.46Å; Y292-L311 HydrophobicContact CD1-CD1 3.97Å; Y292-L311 HydrophobicContact CD1-CD2 3.7Å; Y292-L311 HydrophobicContact CE1-CD1 4.06Å; Y292-L311 HydrophobicContact CE1-CD2 3.9Å; Y292-L311 HydrophobicContact CG-CD2 4.22Å; Y292-Y315 HydrophobicContact CE2-CE2 4.4Å; Y292-Y315 WeakPolarHBondContact CE2-OH 3.36Å; Y292-Y315 PolarHBondContact OH-OH 3.02Å; Y292-Y315 VanDerWaalsContact OH-OH 3.11Å
293N97.4Very high94.6Very high0 Ų020 Ų200%010%0.096CC..Hα-helixtrans-63.5-41.3174.3-172.578.7000112M240 G259 T260 Y263 L289 R290 A295 L296 L297M240-N293 HydrophobicContact CE-CB 4.21Å; G259-N293 VanDerWaalsContact CA-OD1 3.28Å; G259-N293 WeakPolarHBondContact CA-OD1 3.44Å; G259-N293 PolarHBondContact N-OD1 3.15Å; T260-N293 PolarHBondContact N-OD1 3.28Å; T260-N293 PolarHBondContact O-ND2 2.95Å; T260-N293 PolarHBondContact O-OD1 2.97Å; Y263-N293 HydrophobicContact CD1-CB 3.81Å; Y263-N293 VanDerWaalsContact CD1-OD1 3.27Å; Y263-N293 WeakPolarHBondContact CD1-OD1 3.48Å; Y263-N293 HydrophobicContact CE1-CB 4.05Å; L289-N293 WeakPolarHBondContact O-CB 3.49Å; L289-N293 PolarHBondContact O-N 3.02Å; R290-N293 WeakPolarHBondContact O-CB 3.29Å; R290-N293 PolarHBondContact O-N 3.16Å; N293-A295 VanDerWaalsContact C-N 3.29Å; N293-A295 PolarHBondContact O-N 3.44Å; N293-L296 WeakPolarHBondContact O-CB 3.09Å; N293-L296 PolarHBondContact O-N 3.42Å; N293-L297 WeakPolarHBondContact O-CG 3.21Å; N293-L297 PolarHBondContact O-N 3.34Å
294D93.7Very high94.6Very high42 Ų4220.2 Ų20.223%0.22510%0.097CC..Hα-helixtrans-61.2-39.8174.4-72.5-9.9000110.8R290 Q291 L297 I298R290-D294 PolarHBondContact O-N 2.85Å; Q291-D294 PolarHBondContact O-N 3.42Å; D294-L297 PolarHBondContact O-N 3.07Å; D294-I298 VanDerWaalsContact O-CG1 3.26Å; D294-I298 WeakPolarHBondContact O-CG1 3.35Å; D294-I298 PolarHBondContact O-N 2.95Å
295A95.4Very high94.6Very high0 Ų021.7 Ų21.70%010%0.104CC..Hα-helixtrans-63.9-39.6173.600000112.5I236 Q291 Y292 N293 I298 N299 A307 L311I236-A295 HydrophobicContact CD1-CB 4.03Å; Q291-A295 PolarHBondContact O-N 3.19Å; Y292-A295 WeakPolarHBondContact O-CB 3.42Å; Y292-A295 PolarHBondContact O-N 2.69Å; N293-A295 VanDerWaalsContact C-N 3.29Å; N293-A295 PolarHBondContact O-N 3.44Å; A295-I298 PolarHBondContact O-N 3.33Å; A295-N299 WeakPolarHBondContact O-CB 3.49Å; A295-N299 PolarHBondContact O-N 3.21Å; A295-A307 HydrophobicContact CB-CB 4.28Å; A295-A307 WeakPolarHBondContact O-CB 3.41Å; A295-L311 HydrophobicContact CB-CD1 3.72Å; A295-L311 HydrophobicContact CB-CD2 4.06Å; A295-L311 HydrophobicContact CB-CG 3.74Å
296L95.6Very high94.4Very high11 Ų1121.8 Ų21.86%0.05811%0.105CC..Hα-helixtrans-63-41.2172.8-72174.5000112.3I236 K237 M240 C258 Y292 N293 N299 D300I236-L296 HydrophobicContact CB-CD2 3.92Å; I236-L296 HydrophobicContact CB-CG 4.37Å; I236-L296 HydrophobicContact CD1-CD2 4.44Å; I236-L296 HydrophobicContact CG2-CD1 4.06Å; I236-L296 HydrophobicContact CG2-CD2 3.81Å; I236-L296 HydrophobicContact CG2-CG 3.68Å; K237-L296 HydrophobicContact CG-CD1 4.02Å; K237-L296 HydrophobicContact CG-CD2 4.47Å; M240-L296 HydrophobicContact SD-CD1 3.67Å; C258-L296 HydrophobicContact CB-CD1 4Å; Y292-L296 PolarHBondContact O-N 3.46Å; N293-L296 WeakPolarHBondContact O-CB 3.09Å; N293-L296 PolarHBondContact O-N 3.42Å; L296-N299 WeakPolarHBondContact O-CB 3.36Å; L296-N299 PolarHBondContact O-N 2.96Å; L296-D300 PolarHBondContact O-N 2.86Å
297L91.4Very high94.4Very high31 Ų3121.8 Ų21.816%0.16211%0.105CC..Hα-helixtrans-65.6-39.2176.4-68.1173.5000111.9G259 N293 D294 T301G259-L297 VanDerWaalsContact O-CD2 3.29Å; G259-L297 WeakPolarHBondContact O-CD2 3.49Å; N293-L297 WeakPolarHBondContact O-CG 3.21Å; N293-L297 PolarHBondContact O-N 3.34Å; D294-L297 PolarHBondContact O-N 3.07Å; L297-T301 PolarHBondContact O-N 2.92Å; L297-T301 PolarHBondContact O-OG1 3.1Å
298I91.4Very high94.4Very high15 Ų1519.7 Ų19.78%0.0779%0.094CC..Hα-helixtrans-64.1-44172.1-66.9163.1000109.8D294 A295 D300 T301 L302 D306 A307D294-I298 VanDerWaalsContact O-CG1 3.26Å; D294-I298 WeakPolarHBondContact O-CG1 3.35Å; D294-I298 PolarHBondContact O-N 2.95Å; A295-I298 PolarHBondContact O-N 3.33Å; I298-D300 PolarHBondContact O-N 3.31Å; I298-T301 PolarHBondContact O-N 2.72Å; I298-L302 HydrophobicContact CG2-CB 4.27Å; I298-L302 HydrophobicContact CG2-CD1 4.23Å; I298-L302 WeakPolarHBondContact O-CA 3.43Å; I298-L302 WeakPolarHBondContact O-CB 3.47Å; I298-L302 PolarHBondContact O-N 3.01Å; I298-D306 HydrophobicContact CG2-CB 3.88Å; I298-A307 HydrophobicContact CB-CB 4.08Å; I298-A307 HydrophobicContact CG2-CB 3.89Å
299N93.3Very high94.3Very high2 Ų223.4 Ų23.41%0.01111%0.107CC..Hα-helixtrans-59.8-46.3178.5-177.940.1000111.6R227 D230 F232 A295 L296 T301 M304 A307 N352R227-N299 PolarHBondContact NH1-ND2 3.42Å; R227-N299 PolarHBondContact NH1-OD1 3.35Å; R227-N299 PolarHBondContact NH2-O 3.36Å; R227-N299 PolarHBondContact NH2-OD1 2.97Å; D230-N299 PolarHBondContact OD1-ND2 3.37Å; D230-N299 PolarHBondContact OD2-ND2 3.48Å; F232-N299 HydrophobicContact CD1-CB 4.22Å; F232-N299 HydrophobicContact CE1-CB 4.17Å; A295-N299 WeakPolarHBondContact O-CB 3.49Å; A295-N299 PolarHBondContact O-N 3.21Å; L296-N299 WeakPolarHBondContact O-CB 3.36Å; L296-N299 PolarHBondContact O-N 2.96Å; N299-T301 PolarHBondContact O-N 3.21Å; N299-M304 WeakPolarHBondContact OD1-CG 3.43Å; N299-A307 HydrophobicContact CB-CB 4.09Å; N299-N352 PolarHBondContact O-ND2 2.87Å; N299-N352 VanDerWaalsContact O-ND2 3.08Å
300D89.3Confident94.1Very high66 Ų6623.5 Ų23.535%0.35311%0.108SC..Hα-helixtrans-62-30.4178.8-175.975.6000112.8L296 I298 N352 K354L296-D300 PolarHBondContact O-N 2.86Å; I298-D300 PolarHBondContact O-N 3.31Å; D300-N352 PolarHBondContact O-ND2 3.48Å; D300-K354 PolarHBondContact O-NZ 3.31Å; D300-K354 IonicContact OD1-NZ 3.96Å; D300-K354 IonicContact OD2-NZ 2.75Å; D300-K354 PolarHBondContact OD2-NZ 3.01Å
301T86.8Confident94Very high26 Ų2619 Ų1916%0.169%0.091CC..Hα-helixtrans-96-39.8-175.1-49.20000112.9L297 I298 N299 Y458L297-T301 PolarHBondContact O-N 2.92Å; L297-T301 PolarHBondContact O-OG1 3.1Å; I298-T301 PolarHBondContact O-N 2.72Å; N299-T301 PolarHBondContact O-N 3.21Å; T301-Y458 HydrophobicContact CG2-CD1 3.97Å; T301-Y458 HydrophobicContact CG2-CE1 3.79Å; T301-Y458 WeakPolarHBondContact O-CE1 3.03Å; T301-Y458 VanDerWaalsContact O-CZ 3.27Å; T301-Y458 PolarHBondContact O-OH 2.9Å
302L92.1Very high94Very high1 Ų119.8 Ų19.81%0.00510%0.095CC..SBendtrans-125.5-156.7-166.9-62.1172.6000111.1I298 D306 N352 M355 C386 L387 Y458I298-L302 HydrophobicContact CG2-CB 4.27Å; I298-L302 HydrophobicContact CG2-CD1 4.23Å; I298-L302 WeakPolarHBondContact O-CA 3.43Å; I298-L302 WeakPolarHBondContact O-CB 3.47Å; I298-L302 PolarHBondContact O-N 3.01Å; L302-D306 HydrophobicContact CB-CB 4.48Å; L302-N352 VanDerWaalsContact O-CB 3.3Å; L302-N352 WeakPolarHBondContact O-CB 3.29Å; L302-N352 PolarHBondContact O-ND2 3.49Å; L302-M355 HydrophobicContact CD2-SD 4.15Å; L302-C386 HydrophobicContact CD1-CB 3.69Å; L302-L387 HydrophobicContact CD2-CD1 4.25Å; L302-L387 HydrophobicContact CD2-CD2 3.47Å; L302-L387 VanDerWaalsContact CD2-CD2 3.47Å; L302-L387 HydrophobicContact CD2-CG 3.61Å; L302-Y458 HydrophobicContact CD2-CE1 3.87Å
303R93.4Very high93.7Very high38 Ų3824.9 Ų24.914%0.14312%0.119CC..  trans-77.9146.7176.6-53171.7-67.1-176.82110.2M305 D306 A307 M355 C386 D389R303-M305 PolarHBondContact O-N 3.37Å; R303-D306 WeakPolarHBondContact CB-OD2 3.48Å; R303-D306 IonicContact CZ-OD1 2.81Å; R303-D306 IonicContact CZ-OD2 3.12Å; R303-D306 PolarHBondContact N-OD2 3.34Å; R303-D306 IonicContact NE-OD1 2.89Å; R303-D306 IonicContact NE-OD2 3.23Å; R303-D306 PolarHBondContact NE-OD2 2.93Å; R303-D306 IonicContact NH2-OD1 2.98Å; R303-D306 PolarHBondContact NH2-OD1 2.9Å; R303-D306 IonicContact NH2-OD2 2.89Å; R303-D306 PolarHBondContact NH2-OD2 2.98Å; R303-D306 WeakPolarHBondContact O-CB 3.43Å; R303-D306 PolarHBondContact O-N 2.7Å; R303-A307 PolarHBondContact O-N 3.35Å; R303-M355 HydrophobicContact CG-CE 3.98Å; R303-M355 HydrophobicContact CG-CG 4.34Å; R303-C386 PolarHBondContact NH2-O 2.76Å; R303-D389 IonicContact CZ-OD2 3.41Å; R303-D389 IonicContact NH1-OD2 3.6Å; R303-D389 PolarHBondContact NH1-OD2 3.42Å; R303-D389 IonicContact NH2-OD2 2.69Å; R303-D389 PolarHBondContact NH2-OD2 3.06Å
304M95.1Very high93.4Very high8 Ų826.5 Ų26.54%0.03913%0.126CC..Hα-helixtrans-55.7-38.4171.7-69.9177.8-66.200111.9F232 N299 D306 A307 Y308 F344 A345 Y350F232-M304 HydrophobicContact CB-CG 4.01Å; F232-M304 HydrophobicContact CB-SD 3.51Å; F232-M304 VanDerWaalsContact CB-SD 3.51Å; F232-M304 HydrophobicContact CD1-CB 4.27Å; F232-M304 HydrophobicContact CD1-CG 4.1Å; F232-M304 HydrophobicContact CD2-CB 4.42Å; F232-M304 HydrophobicContact CG-CB 4.16Å; F232-M304 HydrophobicContact CG-CG 4.04Å; F232-M304 HydrophobicContact CG-SD 4.14Å; N299-M304 WeakPolarHBondContact OD1-CG 3.43Å; M304-D306 PolarHBondContact O-N 3.27Å; M304-A307 WeakPolarHBondContact O-CA 3.29Å; M304-A307 WeakPolarHBondContact O-CB 3.27Å; M304-A307 PolarHBondContact O-N 2.79Å; M304-Y308 PolarHBondContact O-N 2.8Å; M304-F344 VanDerWaalsContact CE-O 3.23Å; M304-F344 WeakPolarHBondContact CE-O 3.25Å; M304-A345 HydrophobicContact CB-CB 3.85Å; M304-Y350 WeakPolarHBondContact CE-O 3.37Å
305M95Very high93.4Very high37 Ų3724.7 Ų24.718%0.18212%0.116CC..Hα-helixtrans-60.4-31177.5-167.256.654.400113.1R303 Y308 R309 A345 A346R303-M305 PolarHBondContact O-N 3.37Å; M305-Y308 HydrophobicContact SD-CD1 3.91Å; M305-R309 WeakPolarHBondContact O-CB 3.34Å; M305-R309 VanDerWaalsContact O-CG 3.31Å; M305-R309 WeakPolarHBondContact O-CG 3.34Å; M305-R309 PolarHBondContact O-N 3.38Å; M305-A345 VanDerWaalsContact CE-C 3.49Å; M305-A345 HydrophobicContact CE-CB 3.64Å; M305-A345 HydrophobicContact SD-CB 4.47Å; M305-A346 HydrophobicContact CE-CB 3.93Å
306D94.6Very high93.2Very high3 Ų329.3 Ų29.32%0.01614%0.14CC..Hα-helixtrans-71.4-36.2175.3-64.9-49.7000111.6I298 L302 R303 M304 S310 C386I298-D306 HydrophobicContact CG2-CB 3.88Å; L302-D306 HydrophobicContact CB-CB 4.48Å; R303-D306 WeakPolarHBondContact CB-OD2 3.48Å; R303-D306 IonicContact CZ-OD1 2.81Å; R303-D306 IonicContact CZ-OD2 3.12Å; R303-D306 PolarHBondContact N-OD2 3.34Å; R303-D306 IonicContact NE-OD1 2.89Å; R303-D306 IonicContact NE-OD2 3.23Å; R303-D306 PolarHBondContact NE-OD2 2.93Å; R303-D306 IonicContact NH2-OD1 2.98Å; R303-D306 PolarHBondContact NH2-OD1 2.9Å; R303-D306 IonicContact NH2-OD2 2.89Å; R303-D306 PolarHBondContact NH2-OD2 2.98Å; R303-D306 WeakPolarHBondContact O-CB 3.43Å; R303-D306 PolarHBondContact O-N 2.7Å; M304-D306 PolarHBondContact O-N 3.27Å; D306-S310 PolarHBondContact O-N 2.66Å; D306-C386 HydrophobicContact CB-CB 4.07Å
307A95.4Very high92.6Very high0 Ų033.1 Ų33.10%017%0.165CC..Hα-helixtrans-69.2-41.717400000111.6F232 A295 I298 N299 R303 M304 S310 L311F232-A307 HydrophobicContact CE1-CB 3.59Å; F232-A307 HydrophobicContact CZ-CB 3.81Å; A295-A307 HydrophobicContact CB-CB 4.28Å; A295-A307 WeakPolarHBondContact O-CB 3.41Å; I298-A307 HydrophobicContact CB-CB 4.08Å; I298-A307 HydrophobicContact CG2-CB 3.89Å; N299-A307 HydrophobicContact CB-CB 4.09Å; R303-A307 PolarHBondContact O-N 3.35Å; M304-A307 WeakPolarHBondContact O-CA 3.29Å; M304-A307 WeakPolarHBondContact O-CB 3.27Å; M304-A307 PolarHBondContact O-N 2.79Å; A307-S310 VanDerWaalsContact O-CB 3.23Å; A307-S310 WeakPolarHBondContact O-CB 3.32Å; A307-S310 PolarHBondContact O-N 2.88Å; A307-L311 PolarHBondContact O-N 2.99Å
308Y96.8Very high92.2Very high4 Ų433.4 Ų33.42%0.01616%0.164CC..Hα-helixtrans-59.2-52.6174.5171.4-101.1000111.8M304 M305 S310 L311 E312 Q338 L341 K342M304-Y308 PolarHBondContact O-N 2.8Å; M305-Y308 HydrophobicContact SD-CD1 3.91Å; Y308-S310 PolarHBondContact O-N 3.15Å; Y308-S310 VanDerWaalsContact O-N 3.15Å; Y308-L311 PolarHBondContact O-N 2.8Å; Y308-E312 HydrophobicContact CE1-CB 4.4Å; Y308-E312 PolarHBondContact O-N 3.36Å; Y308-E312 PolarHBondContact OH-OE1 3.32Å; Y308-Q338 HydrophobicContact CE2-CG 4.02Å; Y308-Q338 WeakPolarHBondContact CE2-O 3.23Å; Y308-Q338 VanDerWaalsContact OH-CG 3.24Å; Y308-Q338 WeakPolarHBondContact OH-CG 3.41Å; Y308-Q338 PolarHBondContact OH-NE2 2.86Å; Y308-L341 HydrophobicContact CD2-CB 3.98Å; Y308-L341 HydrophobicContact CE2-CB 4.21Å; Y308-K342 HydrophobicContact CD2-CB 4.43Å; Y308-K342 HydrophobicContact CE1-CB 4.28Å; Y308-K342 HydrophobicContact CE1-CD 4.23Å; Y308-K342 HydrophobicContact CE1-CG 4.06Å; Y308-K342 HydrophobicContact CE2-CB 3.84Å
309R94.9Very high91.5Very high82 Ų8236 Ų3631%0.30918%0.181SC..Hα-helixtrans-57.7-30.7177.2-72.9177.6-172.4159.57112.3M305 L311 E312 E313 D389M305-R309 WeakPolarHBondContact O-CB 3.34Å; M305-R309 VanDerWaalsContact O-CG 3.31Å; M305-R309 WeakPolarHBondContact O-CG 3.34Å; M305-R309 PolarHBondContact O-N 3.38Å; R309-L311 VanDerWaalsContact C-N 3.34Å; R309-E312 PolarHBondContact O-N 2.78Å; R309-E313 WeakPolarHBondContact O-CB 3.38Å; R309-E313 VanDerWaalsContact O-CG 3.24Å; R309-E313 WeakPolarHBondContact O-CG 3.4Å; R309-E313 PolarHBondContact O-N 2.92Å; R309-D389 IonicContact NH1-OD2 3.38Å; R309-D389 PolarHBondContact NH1-OD2 3.34Å
310S93.2Very high90.7Very high2 Ų242.7 Ų42.71%0.01422%0.215CC..Hα-helixtrans-63.1-37.6172.9-172.10000114.3Q291 D306 A307 Y308 R382Q291-S310 PolarHBondContact NE2-O 3.01Å; Q291-S310 PolarHBondContact NE2-OG 3.17Å; D306-S310 PolarHBondContact O-N 2.66Å; A307-S310 VanDerWaalsContact O-CB 3.23Å; A307-S310 WeakPolarHBondContact O-CB 3.32Å; A307-S310 PolarHBondContact O-N 2.88Å; Y308-S310 PolarHBondContact O-N 3.15Å; Y308-S310 VanDerWaalsContact O-N 3.15Å; S310-R382 PolarHBondContact OG-NE 2.93Å; S310-R382 PolarHBondContact OG-NH1 2.82Å
311L95.5Very high90.3Very high0 Ų040.6 Ų40.60%021%0.205CC..Hα-helixtrans-77.5-43.5175.9-67.4166000110.4I236 Q291 Y292 A295 A307 Y308 R309 E313 F314 Y315 F334I236-L311 HydrophobicContact CD1-CD1 3.89Å; I236-L311 HydrophobicContact CG1-CD1 4.41Å; Q291-L311 HydrophobicContact CG-CD2 3.84Å; Y292-L311 HydrophobicContact CD1-CD1 3.97Å; Y292-L311 HydrophobicContact CD1-CD2 3.7Å; Y292-L311 HydrophobicContact CE1-CD1 4.06Å; Y292-L311 HydrophobicContact CE1-CD2 3.9Å; Y292-L311 HydrophobicContact CG-CD2 4.22Å; A295-L311 HydrophobicContact CB-CD1 3.72Å; A295-L311 HydrophobicContact CB-CD2 4.06Å; A295-L311 HydrophobicContact CB-CG 3.74Å; A307-L311 PolarHBondContact O-N 2.99Å; Y308-L311 PolarHBondContact O-N 2.8Å; R309-L311 VanDerWaalsContact C-N 3.34Å; L311-E313 PolarHBondContact O-N 2.73Å; L311-F314 WeakPolarHBondContact O-CB 3.28Å; L311-F314 PolarHBondContact O-N 3.17Å; L311-F314 VanDerWaalsContact O-N 3.1Å; L311-Y315 HydrophobicContact CD2-CE2 4.42Å; L311-Y315 WeakPolarHBondContact O-CD2 3.3Å; L311-Y315 PolarHBondContact O-N 3.42Å; L311-F334 HydrophobicContact CB-CD2 4.32Å; L311-F334 HydrophobicContact CB-CE2 3.51Å; L311-F334 HydrophobicContact CB-CZ 3.98Å; L311-F334 HydrophobicContact CD1-CE2 4.48Å
312E95.4Very high90.2Very high47 Ų4739.9 Ų39.922%0.2220%0.201CC..Hα-helixtrans-54.4-55.1177.3-171.1173.5-124.600111.4Y308 R309 F314 Y315 D316 F334 Q338Y308-E312 HydrophobicContact CE1-CB 4.4Å; Y308-E312 PolarHBondContact O-N 3.36Å; Y308-E312 PolarHBondContact OH-OE1 3.32Å; R309-E312 PolarHBondContact O-N 2.78Å; E312-F314 PolarHBondContact O-N 3.06Å; E312-F314 VanDerWaalsContact O-N 3.17Å; E312-Y315 PolarHBondContact O-N 3.42Å; E312-Y315 VanDerWaalsContact O-N 3.16Å; E312-D316 WeakPolarHBondContact O-CB 3.46Å; E312-D316 PolarHBondContact O-N 3.11Å; E312-F334 HydrophobicContact CB-CZ 4.49Å; E312-Q338 PolarHBondContact OE1-NE2 2.84Å
313E92Very high89.9Confident107 Ų10742.7 Ų42.750%0.522%0.216SC..Hα-helixtrans-56.5-35.7176.5-73.4168.2-174.900113.1R309 L311 R382R309-E313 WeakPolarHBondContact O-CB 3.38Å; R309-E313 VanDerWaalsContact O-CG 3.24Å; R309-E313 WeakPolarHBondContact O-CG 3.4Å; R309-E313 PolarHBondContact O-N 2.92Å; L311-E313 PolarHBondContact O-N 2.73Å; E313-R382 IonicContact OE1-NH2 3.53Å; E313-R382 IonicContact OE2-CZ 3.38Å; E313-R382 IonicContact OE2-NH1 3.58Å; E313-R382 IonicContact OE2-NH2 2.81Å; E313-R382 PolarHBondContact OE2-NH2 2.97Å
314F91.8Very high89.8Confident35 Ų3543.2 Ų43.215%0.15422%0.221CC..Hα-helixtrans-70.3-47.2179.1174.8-97.1000111.2H288 Q291 L311 E312 T317 K318H288-F314 AromaticContact CE1-CE1 3.67Å; H288-F314 AromaticContact ND1-CE1 3.73Å; H288-F314 AromaticContact NE2-CE1 3.94Å; H288-F314 AromaticContact NE2-CZ 3.92Å; Q291-F314 HydrophobicContact CB-CD1 4.34Å; Q291-F314 HydrophobicContact CB-CE1 4.31Å; Q291-F314 HydrophobicContact CB-CE2 4.48Å; Q291-F314 HydrophobicContact CB-CG 4.43Å; Q291-F314 HydrophobicContact CB-CZ 4.38Å; Q291-F314 HydrophobicContact CG-CB 3.92Å; Q291-F314 HydrophobicContact CG-CD1 3.79Å; Q291-F314 HydrophobicContact CG-CD2 3.96Å; Q291-F314 HydrophobicContact CG-CE1 4.25Å; Q291-F314 HydrophobicContact CG-CE2 4.41Å; Q291-F314 HydrophobicContact CG-CG 3.62Å; L311-F314 WeakPolarHBondContact O-CB 3.28Å; L311-F314 PolarHBondContact O-N 3.17Å; L311-F314 VanDerWaalsContact O-N 3.1Å; E312-F314 PolarHBondContact O-N 3.06Å; E312-F314 VanDerWaalsContact O-N 3.17Å; F314-T317 PolarHBondContact O-OG1 3.07Å; F314-K318 HydrophobicContact CE1-CG 4.48Å; F314-K318 WeakPolarHBondContact O-CG 3.19Å
315Y93.8Very high89.6Confident3 Ų345.3 Ų45.31%0.01225%0.245CC..Hα-helixtrans-76.6-29.6-176.8-79.1-77.1000113.4H288 Y292 L311 E312 T317 K318 V319 L330 V331 F334H288-Y315 AromaticContact CE1-CE1 3.62Å; H288-Y315 AromaticContact ND1-CE1 3.49Å; H288-Y315 WeakPolarHBondContact ND1-CE1 3.27Å; H288-Y315 AromaticContact ND1-CZ 3.49Å; H288-Y315 PolarHBondContact ND1-OH 2.95Å; Y292-Y315 HydrophobicContact CE2-CE2 4.4Å; Y292-Y315 WeakPolarHBondContact CE2-OH 3.36Å; Y292-Y315 PolarHBondContact OH-OH 3.02Å; Y292-Y315 VanDerWaalsContact OH-OH 3.11Å; L311-Y315 HydrophobicContact CD2-CE2 4.42Å; L311-Y315 WeakPolarHBondContact O-CD2 3.3Å; L311-Y315 PolarHBondContact O-N 3.42Å; E312-Y315 PolarHBondContact O-N 3.42Å; E312-Y315 VanDerWaalsContact O-N 3.16Å; Y315-T317 PolarHBondContact O-N 3.48Å; Y315-K318 WeakPolarHBondContact O-CA 3.47Å; Y315-K318 WeakPolarHBondContact O-CB 3.28Å; Y315-K318 PolarHBondContact O-N 3.41Å; Y315-V319 WeakPolarHBondContact O-CG2 3.44Å; Y315-V319 PolarHBondContact O-N 3.35Å; Y315-V319 VanDerWaalsContact O-N 3.13Å; Y315-L330 WeakPolarHBondContact CE1-O 3.46Å; Y315-V331 HydrophobicContact CD1-CG2 4.17Å; Y315-V331 HydrophobicContact CE1-CG2 4.41Å; Y315-F334 VanDerWaalsContact CB-CD1 3.42Å; Y315-F334 HydrophobicContact CD1-CB 3.91Å; Y315-F334 HydrophobicContact CD1-CD1 4.17Å; Y315-F334 HydrophobicContact CD1-CG 4.18Å; Y315-F334 HydrophobicContact CD2-CB 3.72Å; Y315-F334 AromaticContact CD2-CD1 3.42Å; Y315-F334 HydrophobicContact CD2-CD1 3.42Å; Y315-F334 VanDerWaalsContact CD2-CD1 3.42Å; Y315-F334 AromaticContact CD2-CD2 3.55Å; Y315-F334 HydrophobicContact CD2-CD2 3.55Å; Y315-F334 AromaticContact CD2-CE1 3.86Å; Y315-F334 HydrophobicContact CD2-CE1 3.86Å; Y315-F334 AromaticContact CD2-CE2 4Å; Y315-F334 HydrophobicContact CD2-CE2 4Å; Y315-F334 AromaticContact CD2-CG 3.23Å; Y315-F334 HydrophobicContact CD2-CG 3.23Å; Y315-F334 HydrophobicContact CD2-CZ 4.13Å; Y315-F334 HydrophobicContact CE1-CB 3.84Å; Y315-F334 HydrophobicContact CE1-CG 4.43Å; Y315-F334 HydrophobicContact CE2-CB 3.65Å; Y315-F334 HydrophobicContact CE2-CD1 4.22Å; Y315-F334 AromaticContact CE2-CD2 3.68Å; Y315-F334 HydrophobicContact CE2-CD2 3.68Å; Y315-F334 HydrophobicContact CE2-CE2 4.41Å; Y315-F334 AromaticContact CE2-CG 3.56Å; Y315-F334 HydrophobicContact CE2-CG 3.56Å; Y315-F334 HydrophobicContact CG-CB 3.86Å; Y315-F334 AromaticContact CG-CD1 3.4Å; Y315-F334 HydrophobicContact CG-CD1 3.4Å; Y315-F334 VanDerWaalsContact CG-CD1 3.4Å; Y315-F334 HydrophobicContact CG-CD2 4.36Å; Y315-F334 HydrophobicContact CG-CE1 4.01Å; Y315-F334 AromaticContact CG-CG 3.6Å; Y315-F334 HydrophobicContact CG-CG 3.6Å
316D89.6Confident89.6Confident97 Ų9743.9 Ų43.952%0.51924%0.238SC..Hα-helixtrans-54.9-38.3174.4-76.6-13000111.8E312 K318E312-D316 WeakPolarHBondContact O-CB 3.46Å; E312-D316 PolarHBondContact O-N 3.11Å; D316-K318 VanDerWaalsContact C-N 3.27Å; D316-K318 PolarHBondContact O-N 3.36Å
317T83.1Confident89.6Confident92 Ų9244.3 Ų44.356%0.56424%0.24SC*.THydrogen-bonded Turntrans-74.5-15.3176.468.10000113.9F314 Y315F314-T317 PolarHBondContact O-OG1 3.07Å; Y315-T317 PolarHBondContact O-N 3.48Å
318K83.9Confident89.5Confident37 Ų3751.3 Ų51.316%0.16127%0.268CS..THydrogen-bonded Turntrans-100.7-23.9-171.5-66.8-68.5-175.9179.70114.3F314 Y315 D316 I320 T321 V331F314-K318 HydrophobicContact CE1-CG 4.48Å; F314-K318 WeakPolarHBondContact O-CG 3.19Å; Y315-K318 WeakPolarHBondContact O-CA 3.47Å; Y315-K318 WeakPolarHBondContact O-CB 3.28Å; Y315-K318 PolarHBondContact O-N 3.41Å; D316-K318 VanDerWaalsContact C-N 3.27Å; D316-K318 PolarHBondContact O-N 3.36Å; K318-I320 PolarHBondContact O-N 3.19Å; K318-I320 VanDerWaalsContact O-N 3.11Å; K318-T321 WeakPolarHBondContact CA-OG1 3.22Å; K318-T321 PolarHBondContact O-N 2.99Å; K318-T321 PolarHBondContact O-OG1 2.85Å; K318-V331 HydrophobicContact CB-CG2 4.14Å
319V76.6Confident89.5Confident70 Ų7054 Ų5442%0.42428%0.28SS..THydrogen-bonded Turntrans-52.6-37.2-178.4179.10000112Y315 V331Y315-V319 WeakPolarHBondContact O-CG2 3.44Å; Y315-V319 PolarHBondContact O-N 3.35Å; Y315-V319 VanDerWaalsContact O-N 3.13Å; V319-V331 HydrophobicContact CG2-CG1 4.29Å
320I76.8Confident89.6Confident142 Ų14250.1 Ų50.173%0.72827%0.265SS*.THydrogen-bonded Turntrans-93.6-8-175-49.1171.2000111.8K318K318-I320 PolarHBondContact O-N 3.19Å; K318-I320 VanDerWaalsContact O-N 3.11Å
321T79.8Confident89.7Confident22 Ų2250.6 Ų50.614%0.13527%0.268CS..  trans-110.516.3-172.267.60000114.1K318 I323 N617 N619K318-T321 WeakPolarHBondContact CA-OG1 3.22Å; K318-T321 PolarHBondContact O-N 2.99Å; K318-T321 PolarHBondContact O-OG1 2.85Å; T321-I323 PolarHBondContact O-N 3.46Å; T321-N617 WeakPolarHBondContact CA-O 3.16Å; T321-N617 WeakPolarHBondContact CB-O 3.46Å; T321-N619 HydrophobicContact CG2-CB 4.23Å
322A85.7Confident89.8Confident10 Ų1051.3 Ų51.38%0.08328%0.275CS..  trans-63.3128.6178.900000111D327 Y328 N617A322-D327 HydrophobicContact CB-CB 3.91Å; A322-Y328 HydrophobicContact CB-CD1 4.14Å; A322-Y328 HydrophobicContact CB-CE1 3.83Å; A322-Y328 HydrophobicContact CB-CE2 4.39Å; A322-N617 PolarHBondContact O-ND2 3.12Å
323I86.6Confident89.9Confident60 Ų6049.7 Ų49.731%0.30827%0.268SS..  trans-103.6-47.7-177.5-53.1-174000111.1T321 D327 C561 C618T321-I323 PolarHBondContact O-N 3.46Å; I323-D327 WeakPolarHBondContact CB-OD2 3.43Å; I323-D327 PolarHBondContact N-OD2 2.99Å; I323-C561 HydrophobicContact CD1-CB 3.94Å; I323-C618 HydrophobicContact CD1-CB 3.76Å
324D90.2Very high90.1Very high50 Ų5044.8 Ų44.827%0.26725%0.245SC..SBendtrans-141.2-178.7-173.769.327.8000112.4R280 T326 D327 Y328R280-D324 WeakPolarHBondContact CD-OD2 3.25Å; R280-D324 IonicContact CZ-OD2 3.64Å; R280-D324 IonicContact NE-OD2 2.96Å; R280-D324 IonicContact NH1-OD1 3.22Å; R280-D324 PolarHBondContact NH1-OD1 3.09Å; R280-D324 IonicContact NH1-OD2 2.63Å; R280-D324 PolarHBondContact NH1-OD2 3.23Å; D324-T326 PolarHBondContact O-N 3.15Å; D324-T326 VanDerWaalsContact O-N 3.12Å; D324-T326 WeakPolarHBondContact OD1-CA 3.19Å; D324-T326 WeakPolarHBondContact OD1-CB 3.4Å; D324-T326 PolarHBondContact OD1-N 3.43Å; D324-T326 PolarHBondContact OD1-OG1 2.82Å; D324-D327 PolarHBondContact O-N 3.46Å; D324-D327 PolarHBondContact OD1-N 2.87Å; D324-Y328 WeakPolarHBondContact O-CD2 2.89Å; D324-Y328 PolarHBondContact O-N 2.87Å
325G91.8Very high90.3Very high51 Ų5147.4 Ų47.453%0.52626%0.258SS..Hα-helixtrans-55.4-26.9-179.900000114.8F329G325-F329 WeakPolarHBondContact O-CB 3.29Å; G325-F329 PolarHBondContact O-N 2.8Å
326T94.6Very high90.5Very high8 Ų854.9 Ų54.95%0.04929%0.293CS..Hα-helixtrans-66.4-45.7175.1-50.10000110.5F246 L281 Q284 D324 F329 L330F246-T326 HydrophobicContact CE1-CG2 3.94Å; L281-T326 HydrophobicContact CG-CG2 4.23Å; Q284-T326 HydrophobicContact CB-CG2 3.99Å; D324-T326 PolarHBondContact O-N 3.15Å; D324-T326 VanDerWaalsContact O-N 3.12Å; D324-T326 WeakPolarHBondContact OD1-CA 3.19Å; D324-T326 WeakPolarHBondContact OD1-CB 3.4Å; D324-T326 PolarHBondContact OD1-N 3.43Å; D324-T326 PolarHBondContact OD1-OG1 2.82Å; T326-F329 PolarHBondContact O-N 3.37Å; T326-L330 HydrophobicContact CG2-CD1 3.67Å; T326-L330 HydrophobicContact CG2-CG 4.3Å; T326-L330 WeakPolarHBondContact O-CB 2.88Å; T326-L330 WeakPolarHBondContact O-CG 2.99Å; T326-L330 PolarHBondContact O-N 2.89Å
327D93.7Very high90.9Very high11 Ų1151 Ų516%0.05927%0.272CS..Hα-helixtrans-67-41.3-178.7-61.4-12.4000110.8R280 A322 I323 D324 L330 V331R280-D327 IonicContact CZ-OD1 3.81Å; R280-D327 IonicContact CZ-OD2 3.61Å; R280-D327 IonicContact NH1-OD1 3.64Å; R280-D327 PolarHBondContact NH1-OD1 3.4Å; R280-D327 IonicContact NH1-OD2 3.18Å; R280-D327 PolarHBondContact NH1-OD2 3.09Å; R280-D327 VanDerWaalsContact NH2-CG 3.28Å; R280-D327 IonicContact NH2-OD1 2.97Å; R280-D327 PolarHBondContact NH2-OD1 3Å; R280-D327 IonicContact NH2-OD2 2.77Å; R280-D327 PolarHBondContact NH2-OD2 3.49Å; A322-D327 HydrophobicContact CB-CB 3.91Å; I323-D327 WeakPolarHBondContact CB-OD2 3.43Å; I323-D327 PolarHBondContact N-OD2 2.99Å; D324-D327 PolarHBondContact O-N 3.46Å; D324-D327 PolarHBondContact OD1-N 2.87Å; D327-L330 PolarHBondContact O-N 2.85Å; D327-V331 WeakPolarHBondContact O-CB 3.42Å; D327-V331 VanDerWaalsContact O-CG2 3.26Å; D327-V331 WeakPolarHBondContact O-CG2 3.32Å; D327-V331 PolarHBondContact O-N 3.06Å
328Y94.5Very high91.5Very high147 Ų14749 Ų4958%0.57626%0.257SS*.Hα-helixtrans-60.9-44.4175.5-69.4-68.8000112A322 D324 G332A322-Y328 HydrophobicContact CB-CD1 4.14Å; A322-Y328 HydrophobicContact CB-CE1 3.83Å; A322-Y328 HydrophobicContact CB-CE2 4.39Å; D324-Y328 WeakPolarHBondContact O-CD2 2.89Å; D324-Y328 PolarHBondContact O-N 2.87Å; Y328-G332 WeakPolarHBondContact O-CA 3.03Å; Y328-G332 PolarHBondContact O-N 3.34Å
329F96.8Very high92.1Very high62 Ų6252.1 Ų52.127%0.27228%0.278SS..Hα-helixtrans-60.7-49.8175.2168.9-101.5000111.7I243 F246 G325 T326 G332 L333I243-F329 HydrophobicContact CG1-CE1 4.26Å; F246-F329 HydrophobicContact CB-CD1 4.06Å; F246-F329 HydrophobicContact CB-CE1 3.43Å; F246-F329 VanDerWaalsContact CB-CE1 3.43Å; F246-F329 HydrophobicContact CB-CE2 4.4Å; F246-F329 HydrophobicContact CB-CZ 3.63Å; F246-F329 AromaticContact CD1-CD1 3.6Å; F246-F329 HydrophobicContact CD1-CD1 3.6Å; F246-F329 AromaticContact CD1-CE1 3.82Å; F246-F329 HydrophobicContact CD1-CE1 3.82Å; F246-F329 HydrophobicContact CD1-CG 4.34Å; F246-F329 HydrophobicContact CD2-CB 4.49Å; F246-F329 AromaticContact CD2-CD1 3.79Å; F246-F329 HydrophobicContact CD2-CD1 3.79Å; F246-F329 HydrophobicContact CD2-CD2 4.01Å; F246-F329 AromaticContact CD2-CE1 3.98Å; F246-F329 HydrophobicContact CD2-CE1 3.98Å; F246-F329 HydrophobicContact CD2-CE2 4.17Å; F246-F329 AromaticContact CD2-CG 3.81Å; F246-F329 HydrophobicContact CD2-CG 3.81Å; F246-F329 HydrophobicContact CD2-CZ 4.16Å; F246-F329 AromaticContact CE1-CD1 3.94Å; F246-F329 HydrophobicContact CE1-CD1 3.94Å; F246-F329 HydrophobicContact CE1-CG 4.4Å; F246-F329 HydrophobicContact CE2-CB 4.05Å; F246-F329 HydrophobicContact CE2-CD1 4.11Å; F246-F329 HydrophobicContact CE2-CD2 4.3Å; F246-F329 AromaticContact CE2-CG 3.87Å; F246-F329 HydrophobicContact CE2-CG 3.87Å; F246-F329 AromaticContact CG-CD1 3.52Å; F246-F329 HydrophobicContact CG-CD1 3.52Å; F246-F329 HydrophobicContact CG-CD2 4.47Å; F246-F329 AromaticContact CG-CE1 3.46Å; F246-F329 HydrophobicContact CG-CE1 3.46Å; F246-F329 VanDerWaalsContact CG-CE1 3.46Å; F246-F329 HydrophobicContact CG-CE2 4.41Å; F246-F329 HydrophobicContact CG-CG 4.05Å; F246-F329 AromaticContact CG-CZ 3.93Å; F246-F329 HydrophobicContact CG-CZ 3.93Å; F246-F329 HydrophobicContact CZ-CB 4.07Å; F246-F329 HydrophobicContact CZ-CD1 4.17Å; F246-F329 HydrophobicContact CZ-CG 4.18Å; G325-F329 WeakPolarHBondContact O-CB 3.29Å; G325-F329 PolarHBondContact O-N 2.8Å; T326-F329 PolarHBondContact O-N 3.37Å; F329-G332 PolarHBondContact O-N 2.95Å; F329-L333 HydrophobicContact CE1-CD2 4.47Å; F329-L333 HydrophobicContact CZ-CD2 4.26Å; F329-L333 VanDerWaalsContact O-CB 3.28Å; F329-L333 WeakPolarHBondContact O-CB 3.29Å; F329-L333 PolarHBondContact O-N 2.94Å
330L96.8Very high93.1Very high0 Ų052.9 Ų52.90%028%0.277CS..Hα-helixtrans-66.7-41.5-175.4-69.2169.1000112.7I243 Q284 H288 Y315 T326 D327 F334I243-L330 HydrophobicContact CD1-CD2 3.86Å; I243-L330 HydrophobicContact CG1-CD2 3.82Å; I243-L330 HydrophobicContact CG2-CD2 4.03Å; Q284-L330 HydrophobicContact CB-CD1 4.16Å; H288-L330 HydrophobicContact CB-CD1 4.3Å; H288-L330 HydrophobicContact CB-CD2 4.09Å; Y315-L330 WeakPolarHBondContact CE1-O 3.46Å; T326-L330 HydrophobicContact CG2-CD1 3.67Å; T326-L330 HydrophobicContact CG2-CG 4.3Å; T326-L330 WeakPolarHBondContact O-CB 2.88Å; T326-L330 WeakPolarHBondContact O-CG 2.99Å; T326-L330 PolarHBondContact O-N 2.89Å; D327-L330 PolarHBondContact O-N 2.85Å; L330-F334 PolarHBondContact O-N 2.99Å
331V95.6Very high94Very high12 Ų1246.1 Ų46.17%0.07324%0.242CC..Hα-helixtrans-70.3-44.7176.5174.30000110.5Y315 K318 V319 D327 L333 F334 Q335Y315-V331 HydrophobicContact CD1-CG2 4.17Å; Y315-V331 HydrophobicContact CE1-CG2 4.41Å; K318-V331 HydrophobicContact CB-CG2 4.14Å; V319-V331 HydrophobicContact CG2-CG1 4.29Å; D327-V331 WeakPolarHBondContact O-CB 3.42Å; D327-V331 VanDerWaalsContact O-CG2 3.26Å; D327-V331 WeakPolarHBondContact O-CG2 3.32Å; D327-V331 PolarHBondContact O-N 3.06Å; V331-L333 PolarHBondContact O-N 2.91Å; V331-F334 PolarHBondContact O-N 2.91Å; V331-Q335 HydrophobicContact CG1-CG 4.27Å; V331-Q335 WeakPolarHBondContact O-CG 3.27Å; V331-Q335 PolarHBondContact O-N 2.95Å
332G96.3Very high94.9Very high15 Ų1549.9 Ų49.916%0.15526%0.257CS..Hα-helixtrans-58.8-46.5177.300000112.1Y328 F329 F334 Q335 E336Y328-G332 WeakPolarHBondContact O-CA 3.03Å; Y328-G332 PolarHBondContact O-N 3.34Å; F329-G332 PolarHBondContact O-N 2.95Å; G332-F334 VanDerWaalsContact C-N 3.27Å; G332-F334 PolarHBondContact O-N 2.87Å; G332-Q335 PolarHBondContact O-N 3.15Å; G332-Q335 VanDerWaalsContact O-N 3.11Å; G332-E336 WeakPolarHBondContact O-CB 2.85Å; G332-E336 WeakPolarHBondContact O-CG 3.25Å; G332-E336 PolarHBondContact O-N 2.87Å
333L97.6Very high95.4Very high12 Ų1254.4 Ų54.46%0.06328%0.28CS..Hα-helixtrans-55.5-41.7176179.965.4000111.9M239 Q242 I243 F329 V331 N337M239-L333 HydrophobicContact CB-CD2 4.38Å; M239-L333 HydrophobicContact CE-CG 4.01Å; M239-L333 WeakPolarHBondContact CE-O 3.11Å; Q242-L333 HydrophobicContact CB-CD1 4.28Å; Q242-L333 HydrophobicContact CB-CD2 4.08Å; Q242-L333 HydrophobicContact CG-CD1 4.37Å; I243-L333 HydrophobicContact CD1-CD2 4.12Å; I243-L333 HydrophobicContact CG1-CD2 3.68Å; F329-L333 HydrophobicContact CE1-CD2 4.47Å; F329-L333 HydrophobicContact CZ-CD2 4.26Å; F329-L333 VanDerWaalsContact O-CB 3.28Å; F329-L333 WeakPolarHBondContact O-CB 3.29Å; F329-L333 PolarHBondContact O-N 2.94Å; V331-L333 PolarHBondContact O-N 2.91Å; L333-N337 PolarHBondContact O-ND2 3.05Å
334F97.1Very high95.8Very high4 Ų453.8 Ų53.82%0.01828%0.275CS..Hα-helixtrans-68.6-46.3176178.9-105.5000112.4M239 L311 E312 Y315 L330 V331 G332 E336 N337 Q338 L341M239-F334 HydrophobicContact CE-CD2 4.5Å; L311-F334 HydrophobicContact CB-CD2 4.32Å; L311-F334 HydrophobicContact CB-CE2 3.51Å; L311-F334 HydrophobicContact CB-CZ 3.98Å; L311-F334 HydrophobicContact CD1-CE2 4.48Å; E312-F334 HydrophobicContact CB-CZ 4.49Å; Y315-F334 VanDerWaalsContact CB-CD1 3.42Å; Y315-F334 HydrophobicContact CD1-CB 3.91Å; Y315-F334 HydrophobicContact CD1-CD1 4.17Å; Y315-F334 HydrophobicContact CD1-CG 4.18Å; Y315-F334 HydrophobicContact CD2-CB 3.72Å; Y315-F334 AromaticContact CD2-CD1 3.42Å; Y315-F334 HydrophobicContact CD2-CD1 3.42Å; Y315-F334 VanDerWaalsContact CD2-CD1 3.42Å; Y315-F334 AromaticContact CD2-CD2 3.55Å; Y315-F334 HydrophobicContact CD2-CD2 3.55Å; Y315-F334 AromaticContact CD2-CE1 3.86Å; Y315-F334 HydrophobicContact CD2-CE1 3.86Å; Y315-F334 AromaticContact CD2-CE2 4Å; Y315-F334 HydrophobicContact CD2-CE2 4Å; Y315-F334 AromaticContact CD2-CG 3.23Å; Y315-F334 HydrophobicContact CD2-CG 3.23Å; Y315-F334 HydrophobicContact CD2-CZ 4.13Å; Y315-F334 HydrophobicContact CE1-CB 3.84Å; Y315-F334 HydrophobicContact CE1-CG 4.43Å; Y315-F334 HydrophobicContact CE2-CB 3.65Å; Y315-F334 HydrophobicContact CE2-CD1 4.22Å; Y315-F334 AromaticContact CE2-CD2 3.68Å; Y315-F334 HydrophobicContact CE2-CD2 3.68Å; Y315-F334 HydrophobicContact CE2-CE2 4.41Å; Y315-F334 AromaticContact CE2-CG 3.56Å; Y315-F334 HydrophobicContact CE2-CG 3.56Å; Y315-F334 HydrophobicContact CG-CB 3.86Å; Y315-F334 AromaticContact CG-CD1 3.4Å; Y315-F334 HydrophobicContact CG-CD1 3.4Å; Y315-F334 VanDerWaalsContact CG-CD1 3.4Å; Y315-F334 HydrophobicContact CG-CD2 4.36Å; Y315-F334 HydrophobicContact CG-CE1 4.01Å; Y315-F334 AromaticContact CG-CG 3.6Å; Y315-F334 HydrophobicContact CG-CG 3.6Å; L330-F334 PolarHBondContact O-N 2.99Å; V331-F334 PolarHBondContact O-N 2.91Å; G332-F334 VanDerWaalsContact C-N 3.27Å; G332-F334 PolarHBondContact O-N 2.87Å; F334-E336 PolarHBondContact O-N 2.92Å; F334-N337 CarbonylContact O-C 3.59Å; F334-N337 PolarHBondContact O-N 3.41Å; F334-Q338 HydrophobicContact CE1-CG 4.23Å; F334-Q338 HydrophobicContact CZ-CG 4.25Å; F334-Q338 WeakPolarHBondContact O-CB 3.44Å; F334-Q338 PolarHBondContact O-N 3.12Å; F334-L341 HydrophobicContact CD2-CD1 4.39Å; F334-L341 HydrophobicContact CE2-CD1 4.12Å
335Q95.6Very high96.1Very high91 Ų9151.8 Ų51.843%0.42527%0.265SS..Hα-helixtrans-61.5-43.1-177.6-73.3175.9-24.600112.3V331 G332 N337 Q338V331-Q335 HydrophobicContact CG1-CG 4.27Å; V331-Q335 WeakPolarHBondContact O-CG 3.27Å; V331-Q335 PolarHBondContact O-N 2.95Å; G332-Q335 PolarHBondContact O-N 3.15Å; G332-Q335 VanDerWaalsContact O-N 3.11Å; Q335-N337 PolarHBondContact O-N 2.87Å; Q335-Q338 PolarHBondContact O-N 2.87Å
336E97.1Very high96.2Very high159 Ų15952.6 Ų52.674%0.74327%0.267SS*.Hα-helixtrans-61.4-31.4177.8-72.4172.5-17300112.5G332 F334G332-E336 WeakPolarHBondContact O-CB 2.85Å; G332-E336 WeakPolarHBondContact O-CG 3.25Å; G332-E336 PolarHBondContact O-N 2.87Å; F334-E336 PolarHBondContact O-N 2.92Å
337N97.9Very high96.2Very high15 Ų1553.6 Ų53.68%0.0827%0.272CS..Hα-helixtrans-102.7-1.3-176.5-68.1-77.3000113.5H235 W238 M239 L333 F334 Q335 V339 E340 L341H235-N337 PolarHBondContact CE1-OD1 3.48Å; H235-N337 VanDerWaalsContact CE1-OD1 3.23Å; H235-N337 WeakPolarHBondContact NE2-CB 3.47Å; H235-N337 PolarHBondContact NE2-OD1 3.4Å; H235-N337 VanDerWaalsContact NE2-OD1 3.12Å; W238-N337 WeakPolarHBondContact CZ3-OD1 3.23Å; M239-N337 HydrophobicContact CE-CB 3.79Å; M239-N337 HydrophobicContact SD-CB 3.97Å; L333-N337 PolarHBondContact O-ND2 3.05Å; F334-N337 CarbonylContact O-C 3.59Å; F334-N337 PolarHBondContact O-N 3.41Å; Q335-N337 PolarHBondContact O-N 2.87Å; N337-V339 PolarHBondContact O-N 2.98Å; N337-E340 PolarHBondContact O-N 3.43Å; N337-L341 WeakPolarHBondContact O-CB 3.26Å; N337-L341 WeakPolarHBondContact O-CG 3.27Å; N337-L341 PolarHBondContact O-N 3.4Å
338Q96.2Very high96Very high52 Ų5257.8 Ų57.824%0.24330%0.3CS..Hα-helixtrans-62-41.6-172.1-175.4-179.414.200112.4Y308 E312 F334 Q335 K342Y308-Q338 HydrophobicContact CE2-CG 4.02Å; Y308-Q338 WeakPolarHBondContact CE2-O 3.23Å; Y308-Q338 VanDerWaalsContact OH-CG 3.24Å; Y308-Q338 WeakPolarHBondContact OH-CG 3.41Å; Y308-Q338 PolarHBondContact OH-NE2 2.86Å; E312-Q338 PolarHBondContact OE1-NE2 2.84Å; F334-Q338 HydrophobicContact CE1-CG 4.23Å; F334-Q338 HydrophobicContact CZ-CG 4.25Å; F334-Q338 WeakPolarHBondContact O-CB 3.44Å; F334-Q338 PolarHBondContact O-N 3.12Å; Q335-Q338 PolarHBondContact O-N 2.87Å; Q338-K342 WeakPolarHBondContact O-CB 3.43Å; Q338-K342 PolarHBondContact O-N 3.32Å
339V96.9Very high95.8Very high101 Ų10159.4 Ų59.461%0.61231%0.305SS*.Hα-helixtrans-67.4-44.5-178.91770000110.7N337 K342 N343N337-V339 PolarHBondContact O-N 2.98Å; V339-K342 PolarHBondContact O-N 3.44Å; V339-N343 PolarHBondContact O-N 3.34Å; V339-N343 PolarHBondContact O-ND2 3.27Å
340E96.9Very high95.5Very high86 Ų8658.8 Ų58.840%0.40230%0.301SS..Hα-helixtrans-65.4-46.7179.6-173.8173.2-161.900111.5H235 N337 K342 N343 F344H235-E340 IonicContact CE1-OE2 3.06Å; H235-E340 PolarHBondContact CE1-OE2 2.95Å; H235-E340 IonicContact ND1-OE2 3.57Å; N337-E340 PolarHBondContact O-N 3.43Å; E340-K342 VanDerWaalsContact C-N 3.28Å; E340-K342 PolarHBondContact O-N 2.9Å; E340-N343 WeakPolarHBondContact O-CB 3.38Å; E340-N343 PolarHBondContact O-N 2.83Å; E340-N343 VanDerWaalsContact O-N 3.12Å; E340-F344 HydrophobicContact CG-CD2 4.05Å; E340-F344 HydrophobicContact CG-CE2 3.45Å; E340-F344 VanDerWaalsContact CG-CE2 3.45Å; E340-F344 HydrophobicContact CG-CZ 3.81Å; E340-F344 WeakPolarHBondContact O-CD2 3.48Å; E340-F344 PolarHBondContact O-N 3.16Å; E340-F344 WeakPolarHBondContact OE1-CZ 3.47Å
341L96.9Very high95Very high0 Ų063.6 Ų63.60%032%0.324CS..Hα-helixtrans-55.4-43.1173.4-78.3175.1000112.2F232 H235 I236 M239 Y308 F334 N337 F344 A345F232-L341 HydrophobicContact CD2-CD2 3.96Å; F232-L341 HydrophobicContact CE2-CB 4.33Å; F232-L341 HydrophobicContact CE2-CD2 3.83Å; H235-L341 HydrophobicContact CB-CD2 4.4Å; I236-L341 HydrophobicContact CG1-CD2 3.92Å; M239-L341 HydrophobicContact CE-CD1 4.43Å; M239-L341 HydrophobicContact SD-CD1 3.84Å; M239-L341 HydrophobicContact SD-CG 4.43Å; Y308-L341 HydrophobicContact CD2-CB 3.98Å; Y308-L341 HydrophobicContact CE2-CB 4.21Å; F334-L341 HydrophobicContact CD2-CD1 4.39Å; F334-L341 HydrophobicContact CE2-CD1 4.12Å; N337-L341 WeakPolarHBondContact O-CB 3.26Å; N337-L341 WeakPolarHBondContact O-CG 3.27Å; N337-L341 PolarHBondContact O-N 3.4Å; L341-F344 PolarHBondContact O-N 2.96Å; L341-A345 VanDerWaalsContact O-CB 3.25Å; L341-A345 WeakPolarHBondContact O-CB 3.34Å; L341-A345 PolarHBondContact O-N 3.43Å
342K97.2Very high94.7Very high102 Ų10263.3 Ų63.344%0.44332%0.322SS..Hα-helixtrans-64.6-40.5178.1-170.2174.6-171.31620111.8Y308 Q338 V339 E340 A345 A346Y308-K342 HydrophobicContact CD2-CB 4.43Å; Y308-K342 HydrophobicContact CE1-CB 4.28Å; Y308-K342 HydrophobicContact CE1-CD 4.23Å; Y308-K342 HydrophobicContact CE1-CG 4.06Å; Y308-K342 HydrophobicContact CE2-CB 3.84Å; Q338-K342 WeakPolarHBondContact O-CB 3.43Å; Q338-K342 PolarHBondContact O-N 3.32Å; V339-K342 PolarHBondContact O-N 3.44Å; E340-K342 VanDerWaalsContact C-N 3.28Å; E340-K342 PolarHBondContact O-N 2.9Å; K342-A345 PolarHBondContact O-N 2.97Å; K342-A346 WeakPolarHBondContact O-CB 3.24Å; K342-A346 PolarHBondContact O-N 3.33Å
343N97Very high94.5Very high104 Ų10464.5 Ų64.556%0.55633%0.327SS*.Hα-helixtrans-64.3-47.2177.4-70.2-20.3000111.3V339 E340 A345 A346 D347V339-N343 PolarHBondContact O-N 3.34Å; V339-N343 PolarHBondContact O-ND2 3.27Å; E340-N343 WeakPolarHBondContact O-CB 3.38Å; E340-N343 PolarHBondContact O-N 2.83Å; E340-N343 VanDerWaalsContact O-N 3.12Å; N343-A345 VanDerWaalsContact C-N 3.31Å; N343-A345 PolarHBondContact O-N 3.45Å; N343-A346 PolarHBondContact O-N 2.88Å; N343-D347 PolarHBondContact O-N 3.1Å
344F96.1Very high94.2Very high47 Ų4764 Ų6421%0.20632%0.324CS..Hα-helixtrans-60.4-42.2174.1-66.6-40.6000111.9P231 F232 H235 M304 E340 L341 A346 D347P231-F344 HydrophobicContact CB-CD1 3.89Å; P231-F344 HydrophobicContact CB-CE1 3.94Å; P231-F344 HydrophobicContact CB-CG 4.21Å; P231-F344 HydrophobicContact CB-CZ 4.26Å; P231-F344 HydrophobicContact CG-CD1 4Å; P231-F344 HydrophobicContact CG-CE1 4.44Å; P231-F344 HydrophobicContact CG-CG 4.38Å; F232-F344 HydrophobicContact CB-CB 3.99Å; F232-F344 HydrophobicContact CD2-CB 4.29Å; H235-F344 HydrophobicContact CB-CD2 4.27Å; H235-F344 HydrophobicContact CB-CE2 4.03Å; M304-F344 VanDerWaalsContact CE-O 3.23Å; M304-F344 WeakPolarHBondContact CE-O 3.25Å; E340-F344 HydrophobicContact CG-CD2 4.05Å; E340-F344 HydrophobicContact CG-CE2 3.45Å; E340-F344 VanDerWaalsContact CG-CE2 3.45Å; E340-F344 HydrophobicContact CG-CZ 3.81Å; E340-F344 WeakPolarHBondContact O-CD2 3.48Å; E340-F344 PolarHBondContact O-N 3.16Å; E340-F344 WeakPolarHBondContact OE1-CZ 3.47Å; L341-F344 PolarHBondContact O-N 2.96Å; F344-A346 VanDerWaalsContact C-N 3.27Å; F344-A346 PolarHBondContact O-N 3.11Å; F344-D347 PolarHBondContact O-N 3.14Å
345A94.9Very high94Very high9 Ų964 Ų647%0.07432%0.324CS..Hα-helixtrans-68.3-24.7-178.100000114.1F232 M304 M305 L341 K342 N343F232-A345 HydrophobicContact CD2-CB 3.99Å; F232-A345 HydrophobicContact CE2-CB 3.98Å; M304-A345 HydrophobicContact CB-CB 3.85Å; M305-A345 VanDerWaalsContact CE-C 3.49Å; M305-A345 HydrophobicContact CE-CB 3.64Å; M305-A345 HydrophobicContact SD-CB 4.47Å; L341-A345 VanDerWaalsContact O-CB 3.25Å; L341-A345 WeakPolarHBondContact O-CB 3.34Å; L341-A345 PolarHBondContact O-N 3.43Å; K342-A345 PolarHBondContact O-N 2.97Å; N343-A345 VanDerWaalsContact C-N 3.31Å; N343-A345 PolarHBondContact O-N 3.45Å
346A94.6Very high93.8Very high67 Ų6762.3 Ų62.355%0.55433%0.326SS*.Hα-helixtrans-88.5-11.317900000113.5M305 K342 N343 F344 P348M305-A346 HydrophobicContact CE-CB 3.93Å; K342-A346 WeakPolarHBondContact O-CB 3.24Å; K342-A346 PolarHBondContact O-N 3.33Å; N343-A346 PolarHBondContact O-N 2.88Å; F344-A346 VanDerWaalsContact C-N 3.27Å; F344-A346 PolarHBondContact O-N 3.11Å; A346-P348 WeakPolarHBondContact O-CD 3.45Å
347D93.9Very high93.7Very high30 Ų3057.7 Ų57.716%0.1630%0.303CS..  trans-80.5116-176.3-169.3-26.6000111.5N343 F344 R349 Y350N343-D347 PolarHBondContact O-N 3.1Å; F344-D347 PolarHBondContact O-N 3.14Å; D347-R349 PolarHBondContact O-N 2.99Å; D347-R349 VanDerWaalsContact OD1-CB 3.23Å; D347-R349 WeakPolarHBondContact OD1-CB 3.18Å; D347-R349 VanDerWaalsContact OD1-CG 3.24Å; D347-R349 WeakPolarHBondContact OD1-CG 3.18Å; D347-R349 PolarHBondContact OD1-N 2.99Å; D347-R349 IonicContact OD1-NE 3.32Å; D347-R349 PolarHBondContact OD1-NE 3.26Å; D347-R349 IonicContact OD2-CZ 2.97Å; D347-R349 IonicContact OD2-NE 3.05Å; D347-R349 PolarHBondContact OD2-NE 3.07Å; D347-R349 IonicContact OD2-NH2 3.2Å; D347-R349 PolarHBondContact OD2-NH2 2.68Å; D347-Y350 HydrophobicContact CB-CD2 3.87Å; D347-Y350 HydrophobicContact CB-CE2 4.08Å; D347-Y350 PolarHBondContact O-N 3.13Å; D347-Y350 WeakPolarHBondContact OD2-CE2 3.36Å
348P89.3Confident93.5Very high99 Ų9957 Ų5764%0.64330%0.3SS*.G310 helixtrans-67.7-16.9-177.728.8-35.6000113.3A346 Y350 E351A346-P348 WeakPolarHBondContact O-CD 3.45Å; P348-Y350 PolarHBondContact O-N 2.75Å; P348-E351 WeakPolarHBondContact O-CB 3.47Å; P348-E351 PolarHBondContact O-N 3.1Å
349R91.1Very high93.4Very high180 Ų18056.7 Ų56.768%0.67930%0.298SS*.G310 helixtrans-64.5-24.7-179.5-63.9178.3-66.8172.40.6113.1D347D347-R349 PolarHBondContact O-N 2.99Å; D347-R349 VanDerWaalsContact OD1-CB 3.23Å; D347-R349 WeakPolarHBondContact OD1-CB 3.18Å; D347-R349 VanDerWaalsContact OD1-CG 3.24Å; D347-R349 WeakPolarHBondContact OD1-CG 3.18Å; D347-R349 PolarHBondContact OD1-N 2.99Å; D347-R349 IonicContact OD1-NE 3.32Å; D347-R349 PolarHBondContact OD1-NE 3.26Å; D347-R349 IonicContact OD2-CZ 2.97Å; D347-R349 IonicContact OD2-NE 3.05Å; D347-R349 PolarHBondContact OD2-NE 3.07Å; D347-R349 IonicContact OD2-NH2 3.2Å; D347-R349 PolarHBondContact OD2-NH2 2.68Å
350Y90.1Very high93.3Very high49 Ų4954.6 Ų54.619%0.19229%0.288CS..G310 helixtrans-108.318.5-178.6-43.9-67.2000112.3P231 M304 D347 P348P231-Y350 HydrophobicContact CG-CD1 3.92Å; P231-Y350 HydrophobicContact CG-CD2 3.54Å; P231-Y350 HydrophobicContact CG-CE1 3.91Å; P231-Y350 HydrophobicContact CG-CE2 3.56Å; P231-Y350 HydrophobicContact CG-CG 3.73Å; M304-Y350 WeakPolarHBondContact CE-O 3.37Å; D347-Y350 HydrophobicContact CB-CD2 3.87Å; D347-Y350 HydrophobicContact CB-CE2 4.08Å; D347-Y350 PolarHBondContact O-N 3.13Å; D347-Y350 WeakPolarHBondContact OD2-CE2 3.36Å; P348-Y350 PolarHBondContact O-N 2.75Å
351E86.6Confident93.1Very high102 Ų10250.9 Ų50.948%0.47727%0.271SS..  trans-59.5149.7-179.6-171.6163.7-156.200112P348 P353P348-E351 WeakPolarHBondContact O-CB 3.47Å; P348-E351 PolarHBondContact O-N 3.1Å; E351-P353 WeakPolarHBondContact O-CD 3.42Å
352N90.3Very high93Very high6 Ų650.9 Ų50.93%0.03227%0.271CS..  trans-71.6118.4-176.9-165.5-26.3000111.1R227 N299 D300 L302 K354 M355R227-N352 VanDerWaalsContact NH2-CB 3.31Å; R227-N352 PolarHBondContact NH2-ND2 2.92Å; N299-N352 PolarHBondContact O-ND2 2.87Å; N299-N352 VanDerWaalsContact O-ND2 3.08Å; D300-N352 PolarHBondContact O-ND2 3.48Å; L302-N352 VanDerWaalsContact O-CB 3.3Å; L302-N352 WeakPolarHBondContact O-CB 3.29Å; L302-N352 PolarHBondContact O-ND2 3.49Å; N352-K354 PolarHBondContact O-N 3.48Å; N352-K354 VanDerWaalsContact O-N 3.15Å; N352-K354 WeakPolarHBondContact OD1-CB 3.36Å; N352-K354 PolarHBondContact OD1-N 3.22Å; N352-M355 HydrophobicContact CB-CB 4.46Å; N352-M355 HydrophobicContact CB-CG 3.89Å; N352-M355 WeakPolarHBondContact O-CB 3.36Å; N352-M355 PolarHBondContact O-N 3.35Å
353P91.7Very high92.8Very high40 Ų4048.9 Ų48.926%0.2627%0.265SS..Hα-helixtrans-63.2-24.9179.626.2-35000112.6V224 E225 R227 E351 M355 A356 K357V224-P353 HydrophobicContact CB-CB 4.16Å; V224-P353 HydrophobicContact CB-CG 4.49Å; V224-P353 HydrophobicContact CG2-CB 4.38Å; V224-P353 HydrophobicContact CG2-CG 4.26Å; E225-P353 VanDerWaalsContact O-CG 3.28Å; E225-P353 WeakPolarHBondContact O-CG 3.41Å; R227-P353 HydrophobicContact CG-CG 4.41Å; E351-P353 WeakPolarHBondContact O-CD 3.42Å; P353-M355 PolarHBondContact O-N 3.33Å; P353-A356 PolarHBondContact O-N 3.48Å; P353-K357 WeakPolarHBondContact O-CB 3.31Å; P353-K357 PolarHBondContact O-N 3.23Å
354K91.4Very high92.5Very high2 Ų246.9 Ų46.91%0.00927%0.269CS..Hα-helixtrans-60.8-33.8172.4-62.6-178.6-169.7173.40111.4V224 D300 N352 L358 Y458 V484 E491V224-K354 HydrophobicContact CG2-CB 4.49Å; V224-K354 HydrophobicContact CG2-CG 3.63Å; D300-K354 PolarHBondContact O-NZ 3.31Å; D300-K354 IonicContact OD1-NZ 3.96Å; D300-K354 IonicContact OD2-NZ 2.75Å; D300-K354 PolarHBondContact OD2-NZ 3.01Å; N352-K354 PolarHBondContact O-N 3.48Å; N352-K354 VanDerWaalsContact O-N 3.15Å; N352-K354 WeakPolarHBondContact OD1-CB 3.36Å; N352-K354 PolarHBondContact OD1-N 3.22Å; K354-L358 WeakPolarHBondContact O-CB 3.44Å; K354-L358 PolarHBondContact O-N 3.46Å; K354-Y458 VanDerWaalsContact C-OH 3.28Å; K354-Y458 HydrophobicContact CB-CE2 4.02Å; K354-Y458 VanDerWaalsContact CB-OH 3.28Å; K354-Y458 WeakPolarHBondContact CB-OH 3.27Å; K354-Y458 WeakPolarHBondContact O-CE2 3.06Å; K354-Y458 PolarHBondContact O-OH 3.32Å; K354-V484 HydrophobicContact CB-CG1 4.3Å; K354-E491 IonicContact NZ-OE1 2.68Å; K354-E491 PolarHBondContact NZ-OE1 3.38Å
355M92.4Very high92.2Very high2 Ų246.7 Ų46.71%0.0127%0.269CS..Hα-helixtrans-70.9-45.6179.5-66.1-66.6-59.900111.3L302 R303 N352 P353 K357 L358 E359 L387 W390 Y458L302-M355 HydrophobicContact CD2-SD 4.15Å; R303-M355 HydrophobicContact CG-CE 3.98Å; R303-M355 HydrophobicContact CG-CG 4.34Å; N352-M355 HydrophobicContact CB-CB 4.46Å; N352-M355 HydrophobicContact CB-CG 3.89Å; N352-M355 WeakPolarHBondContact O-CB 3.36Å; N352-M355 PolarHBondContact O-N 3.35Å; P353-M355 PolarHBondContact O-N 3.33Å; M355-K357 VanDerWaalsContact C-N 3.29Å; M355-K357 PolarHBondContact O-N 3.38Å; M355-L358 PolarHBondContact O-N 3.29Å; M355-E359 PolarHBondContact O-N 2.96Å; M355-L387 HydrophobicContact CE-CD2 4.41Å; M355-L387 HydrophobicContact SD-CD2 4.39Å; M355-W390 HydrophobicContact CE-CB 4.06Å; M355-W390 HydrophobicContact CE-CD2 3.25Å; M355-W390 VanDerWaalsContact CE-CE2 3.42Å; M355-W390 HydrophobicContact CE-CE3 3.81Å; M355-W390 HydrophobicContact CE-CG 3.33Å; M355-W390 HydrophobicContact CE-CZ2 4.07Å; M355-W390 HydrophobicContact CE-CZ3 4.42Å; M355-Y458 PolarHBondContact N-OH 2.92Å; M355-Y458 HydrophobicContact SD-CE1 4.46Å; M355-Y458 PolarHBondContact SD-OH 3.33Å
356A91.9Very high92.1Very high57 Ų5746.7 Ų46.747%0.47127%0.267SS..Hα-helixtrans-61.5-39.6175.100000111.7P353 E359 S360P353-A356 PolarHBondContact O-N 3.48Å; A356-E359 WeakPolarHBondContact O-CB 3.41Å; A356-E359 PolarHBondContact O-N 3.02Å; A356-S360 PolarHBondContact O-N 3.2Å
357K93.5Very high91.8Very high62 Ų6244.1 Ų44.127%0.2725%0.247SC..Hα-helixtrans-66.7-43.8176-173.563.3-174.9161.70112D222 V224 P353 M355 E359 S360 T361 V484D222-K357 HydrophobicContact CB-CD 4.3Å; D222-K357 HydrophobicContact CB-CG 3.95Å; D222-K357 WeakPolarHBondContact OD1-CE 3.5Å; D222-K357 IonicContact OD1-NZ 3.21Å; D222-K357 PolarHBondContact OD1-NZ 3.07Å; V224-K357 HydrophobicContact CG1-CB 3.38Å; V224-K357 HydrophobicContact CG1-CD 4.43Å; V224-K357 HydrophobicContact CG1-CG 3.69Å; P353-K357 WeakPolarHBondContact O-CB 3.31Å; P353-K357 PolarHBondContact O-N 3.23Å; M355-K357 VanDerWaalsContact C-N 3.29Å; M355-K357 PolarHBondContact O-N 3.38Å; K357-E359 VanDerWaalsContact C-N 3.3Å; K357-E359 PolarHBondContact O-N 2.93Å; K357-S360 PolarHBondContact O-N 2.98Å; K357-S360 VanDerWaalsContact O-N 3.17Å; K357-S360 PolarHBondContact O-OG 3.25Å; K357-T361 PolarHBondContact O-N 3.44Å; K357-T361 PolarHBondContact O-OG1 3.32Å; K357-V484 HydrophobicContact CB-CG1 4.31Å; K357-V484 HydrophobicContact CG-CG1 4.24Å
358L94.3Very high91.1Very high0 Ų047.7 Ų47.70%027%0.272CS..Hα-helixtrans-57.6-42.6173.3176.262.5000111.8K354 M355 S360 T361 L362 L376 L387 W390 V456 Y458K354-L358 WeakPolarHBondContact O-CB 3.44Å; K354-L358 PolarHBondContact O-N 3.46Å; M355-L358 PolarHBondContact O-N 3.29Å; L358-S360 PolarHBondContact O-N 3.06Å; L358-T361 PolarHBondContact O-N 3.46Å; L358-L362 HydrophobicContact CD1-CD1 4.35Å; L358-L362 HydrophobicContact CD1-CG 4.27Å; L358-L362 HydrophobicContact CG-CD1 4.28Å; L358-L362 WeakPolarHBondContact O-CG 3.42Å; L358-L362 PolarHBondContact O-N 2.85Å; L358-L376 HydrophobicContact CD1-CD1 3.77Å; L358-L376 HydrophobicContact CD1-CD2 4.33Å; L358-L376 HydrophobicContact CD2-CD1 4.34Å; L358-L376 HydrophobicContact CD2-CD2 3.99Å; L358-L387 HydrophobicContact CD2-CD2 3.87Å; L358-W390 HydrophobicContact CB-CH2 4.4Å; L358-W390 HydrophobicContact CD2-CE3 4.45Å; L358-W390 HydrophobicContact CD2-CH2 3.99Å; L358-W390 HydrophobicContact CD2-CZ3 3.65Å; L358-W390 HydrophobicContact CG-CH2 3.93Å; L358-W390 HydrophobicContact CG-CZ3 4.01Å; L358-V456 HydrophobicContact CD1-CG1 3.77Å; L358-Y458 HydrophobicContact CB-CD2 4.2Å; L358-Y458 HydrophobicContact CB-CE2 3.76Å; L358-Y458 HydrophobicContact CD1-CD2 4.2Å; L358-Y458 HydrophobicContact CD2-CD2 3.91Å; L358-Y458 HydrophobicContact CD2-CE2 3.8Å; L358-Y458 HydrophobicContact CD2-CG 4.36Å; L358-Y458 HydrophobicContact CG-CD2 4.33Å; L358-Y458 HydrophobicContact CG-CE2 4.25Å
359E95.1Very high90.6Very high45 Ų4550.7 Ų50.721%0.2128%0.283CS..Hα-helixtrans-56.4-50.5173.7-172.6167.5-179.500111.3M355 A356 K357 T361 L362 L363 W390 N394 T396 L397M355-E359 PolarHBondContact O-N 2.96Å; A356-E359 WeakPolarHBondContact O-CB 3.41Å; A356-E359 PolarHBondContact O-N 3.02Å; K357-E359 VanDerWaalsContact C-N 3.3Å; K357-E359 PolarHBondContact O-N 2.93Å; E359-T361 VanDerWaalsContact C-N 3.32Å; E359-T361 PolarHBondContact O-N 3.34Å; E359-L362 PolarHBondContact O-N 3.04Å; E359-L363 HydrophobicContact CG-CD1 3.81Å; E359-L363 HydrophobicContact CG-CG 4.38Å; E359-L363 WeakPolarHBondContact O-CB 3.49Å; E359-L363 VanDerWaalsContact O-CG 3.31Å; E359-L363 WeakPolarHBondContact O-CG 3.47Å; E359-L363 PolarHBondContact O-N 3.17Å; E359-W390 HydrophobicContact CB-CH2 4.16Å; E359-W390 HydrophobicContact CB-CZ2 3.92Å; E359-W390 HydrophobicContact CG-CZ2 4.48Å; E359-N394 PolarHBondContact OE1-ND2 2.97Å; E359-N394 PolarHBondContact OE1-OD1 2.73Å; E359-N394 PolarHBondContact OE2-ND2 3.41Å; E359-N394 VanDerWaalsContact OE2-ND2 3.08Å; E359-T396 WeakPolarHBondContact OE1-CB 3.18Å; E359-T396 PolarHBondContact OE1-OG1 3.12Å; E359-L397 HydrophobicContact CG-CD2 4.1Å; E359-L397 HydrophobicContact CG-CG 4.43Å
360S94.1Very high90.2Very high57 Ų5745.9 Ų45.940%0.39927%0.273SS..Hα-helixtrans-61.8-38.4178.974.20000113A356 K357 L358 L363 G364A356-S360 PolarHBondContact O-N 3.2Å; K357-S360 PolarHBondContact O-N 2.98Å; K357-S360 VanDerWaalsContact O-N 3.17Å; K357-S360 PolarHBondContact O-OG 3.25Å; L358-S360 PolarHBondContact O-N 3.06Å; S360-L363 PolarHBondContact O-N 2.83Å; S360-G364 PolarHBondContact O-N 3.11Å
361T93.2Very high89.9Confident8 Ų852.3 Ų52.35%0.04931%0.305CS..Hα-helixtrans-65.7-42177-62.30000111.1K357 L358 E359 G364 L454 V456K357-T361 PolarHBondContact O-N 3.44Å; K357-T361 PolarHBondContact O-OG1 3.32Å; L358-T361 PolarHBondContact O-N 3.46Å; E359-T361 VanDerWaalsContact C-N 3.32Å; E359-T361 PolarHBondContact O-N 3.34Å; T361-G364 PolarHBondContact O-N 3.39Å; T361-L454 HydrophobicContact CG2-CD1 4.42Å; T361-V456 HydrophobicContact CG2-CG2 3.97Å
362L94.4Very high90Very high0 Ų047.5 Ų47.50%028%0.283CS..Hα-helixtrans-65.3-48.5175.3-68.2174.1000110.7L358 E359 G364 Q365 F366 W390 L397 I402 L436 L454L358-L362 HydrophobicContact CD1-CD1 4.35Å; L358-L362 HydrophobicContact CD1-CG 4.27Å; L358-L362 HydrophobicContact CG-CD1 4.28Å; L358-L362 WeakPolarHBondContact O-CG 3.42Å; L358-L362 PolarHBondContact O-N 2.85Å; E359-L362 PolarHBondContact O-N 3.04Å; L362-G364 PolarHBondContact O-N 2.91Å; L362-Q365 PolarHBondContact O-N 3.43Å; L362-Q365 VanDerWaalsContact O-N 3.08Å; L362-F366 HydrophobicContact CB-CD2 4.42Å; L362-F366 HydrophobicContact CD2-CD2 4.31Å; L362-F366 HydrophobicContact CD2-CE2 3.98Å; L362-F366 WeakPolarHBondContact O-CB 3.43Å; L362-F366 VanDerWaalsContact O-CD2 3.28Å; L362-F366 WeakPolarHBondContact O-CD2 3.21Å; L362-F366 PolarHBondContact O-N 3.38Å; L362-W390 HydrophobicContact CD1-CH2 4.16Å; L362-W390 HydrophobicContact CD1-CZ3 4.02Å; L362-L397 HydrophobicContact CB-CD2 3.93Å; L362-L397 HydrophobicContact CD1-CD1 4.16Å; L362-L397 HydrophobicContact CD1-CD2 4.19Å; L362-I402 HydrophobicContact CB-CD1 4.12Å; L362-L436 HydrophobicContact CD1-CD2 4.3Å; L362-L436 HydrophobicContact CD2-CD1 4.07Å; L362-L436 HydrophobicContact CD2-CD2 4.22Å; L362-L454 HydrophobicContact CD2-CD2 4.04Å
363L93.7Very high90.1Very high61 Ų6148.9 Ų48.932%0.31929%0.287SS..Hα-helixtrans-65.2-23.8179.7-66.8173.2000113.6E359 S360 Q365 F366 T396 L397 A400E359-L363 HydrophobicContact CG-CD1 3.81Å; E359-L363 HydrophobicContact CG-CG 4.38Å; E359-L363 WeakPolarHBondContact O-CB 3.49Å; E359-L363 VanDerWaalsContact O-CG 3.31Å; E359-L363 WeakPolarHBondContact O-CG 3.47Å; E359-L363 PolarHBondContact O-N 3.17Å; S360-L363 PolarHBondContact O-N 2.83Å; L363-Q365 VanDerWaalsContact C-N 3.28Å; L363-Q365 PolarHBondContact O-N 2.99Å; L363-F366 VanDerWaalsContact O-O 3.14Å; L363-T396 HydrophobicContact CD1-CG2 3.56Å; L363-T396 HydrophobicContact CD2-CG2 3.98Å; L363-T396 HydrophobicContact CG-CG2 4.43Å; L363-L397 HydrophobicContact CD2-CD2 3.9Å; L363-L397 HydrophobicContact CG-CD2 3.94Å; L363-A400 HydrophobicContact CD2-CB 3.62Å
364G90.7Very high90.2Very high61 Ų6147 Ų4763%0.62928%0.275SS*.Hα-helixtrans-69.4-24.5174.100000113.7S360 T361 L362S360-G364 PolarHBondContact O-N 3.11Å; T361-G364 PolarHBondContact O-N 3.39Å; L362-G364 PolarHBondContact O-N 2.91Å
365Q89.6Confident90.4Very high44 Ų4446.9 Ų46.921%0.20628%0.275CS..Hα-helixtrans-109.9-29-179.4-69.5-66.4-20.600112.9L362 L363 S372 L454L362-Q365 PolarHBondContact O-N 3.43Å; L362-Q365 VanDerWaalsContact O-N 3.08Å; L363-Q365 VanDerWaalsContact C-N 3.28Å; L363-Q365 PolarHBondContact O-N 2.99Å; Q365-S372 VanDerWaalsContact O-CB 3.25Å; Q365-S372 WeakPolarHBondContact O-CB 3.5Å; Q365-S372 PolarHBondContact O-OG 3.29Å; Q365-L454 HydrophobicContact CB-CB 4.43Å; Q365-L454 HydrophobicContact CB-CD2 3.98Å; Q365-L454 HydrophobicContact CG-CB 4.27Å; Q365-L454 HydrophobicContact CG-CD1 4.11Å; Q365-L454 HydrophobicContact CG-CD2 4.04Å; Q365-L454 HydrophobicContact CG-CG 4.34Å
366F91.9Very high90.5Very high8 Ų846.8 Ų46.84%0.03527%0.274CS..  trans-99.5135.1179.8-70.3-89.8000111.2L362 L363 A400 I402 N435 L436 L454L362-F366 HydrophobicContact CB-CD2 4.42Å; L362-F366 HydrophobicContact CD2-CD2 4.31Å; L362-F366 HydrophobicContact CD2-CE2 3.98Å; L362-F366 WeakPolarHBondContact O-CB 3.43Å; L362-F366 VanDerWaalsContact O-CD2 3.28Å; L362-F366 WeakPolarHBondContact O-CD2 3.21Å; L362-F366 PolarHBondContact O-N 3.38Å; L363-F366 VanDerWaalsContact O-O 3.14Å; F366-A400 HydrophobicContact CB-CB 4.39Å; F366-I402 HydrophobicContact CB-CD1 3.89Å; F366-I402 HydrophobicContact CB-CG1 3.8Å; F366-I402 HydrophobicContact CD1-CD1 4.4Å; F366-I402 HydrophobicContact CD1-CG1 3.85Å; F366-I402 HydrophobicContact CD2-CD1 3.94Å; F366-I402 HydrophobicContact CD2-CG1 4.29Å; F366-I402 HydrophobicContact CE1-CG1 4.48Å; F366-I402 HydrophobicContact CG-CD1 3.83Å; F366-I402 HydrophobicContact CG-CG1 3.73Å; F366-N435 HydrophobicContact CE1-CB 4.06Å; F366-N435 VanDerWaalsContact CE1-O 3.29Å; F366-N435 WeakPolarHBondContact CE1-O 3.44Å; F366-N435 VanDerWaalsContact CZ-O 3.25Å; F366-N435 WeakPolarHBondContact CZ-O 3.3Å; F366-L436 HydrophobicContact CE2-CD1 4.4Å; F366-L436 HydrophobicContact CZ-CB 4.3Å; F366-L436 HydrophobicContact CZ-CD1 4.29Å; F366-L454 HydrophobicContact CE2-CD2 4.02Å
367G87.4Confident90.6Very high14 Ų1444.1 Ų44.114%0.14425%0.252CS..BIsolated β-bridgetrans-152.1164.7172.700000111D369 V370 A400G367-D369 PolarHBondContact O-N 3.44Å; G367-D369 VanDerWaalsContact O-N 3.11Å; G367-V370 PolarHBondContact O-N 2.99Å; G367-A400 CarbonylContact C-O 3.53Å
368P79.4Confident90.4Very high105 Ų10541.3 Ų41.368%0.68224%0.24SC*.THydrogen-bonded Turntrans-53.4-35.8-174.7-26.133.8000114.1
369D79.8Confident89.9Confident161 Ų16147.3 Ų47.386%0.86126%0.263SS*.THydrogen-bonded Turntrans-110.510.6-177.6-55.8-55.1000113.1G367G367-D369 PolarHBondContact O-N 3.44Å; G367-D369 VanDerWaalsContact O-N 3.11Å
370V82.1Confident89.4Confident80 Ų8047.8 Ų47.849%0.48527%0.269SS..BIsolated β-bridgetrans-101.9116.8-179.3-171.60000109.3G367 S372G367-V370 PolarHBondContact O-N 2.99Å; V370-S372 VanDerWaalsContact CG1-OG 3.3Å; V370-S372 WeakPolarHBondContact CG1-OG 3.38Å; V370-S372 PolarHBondContact O-N 3.08Å
371Q83.6Confident89Confident183 Ų18348.3 Ų48.386%0.85526%0.262SS*.  trans-78.167.5174.5-66.3-164.82.100111.7
372S89.1Confident88.6Confident2 Ų251.3 Ų51.31%0.01427%0.273CS..  trans-88.8149.1176.8-75.90000112.3Q365 V370 N435 N453Q365-S372 VanDerWaalsContact O-CB 3.25Å; Q365-S372 WeakPolarHBondContact O-CB 3.5Å; Q365-S372 PolarHBondContact O-OG 3.29Å; V370-S372 VanDerWaalsContact CG1-OG 3.3Å; V370-S372 WeakPolarHBondContact CG1-OG 3.38Å; V370-S372 PolarHBondContact O-N 3.08Å; S372-N435 WeakPolarHBondContact O-CB 3.21Å; S372-N453 PolarHBondContact OG-ND2 3.48Å
373R92.1Very high88.4Confident34 Ų3451.8 Ų51.813%0.12828%0.276CS..  trans-134.6117.1173-62-171.8-151.4-156.413.1109.4F429 R430 N435 E451 C452 N453 L454R373-F429 HydrophobicContact CB-CE1 4.3Å; R373-F429 HydrophobicContact CB-CZ 3.84Å; R373-F429 PolarHBondContact NH1-O 3.47Å; R373-R430 VanDerWaalsContact NH1-C 3.3Å; R373-R430 PolarHBondContact NH1-O 3.42Å; R373-N435 WeakPolarHBondContact CA-O 3.41Å; R373-E451 IonicContact NH2-OE1 3.4Å; R373-C452 WeakPolarHBondContact O-CA 3.24Å; R373-C452 PolarHBondContact O-SG 3.05Å; R373-N453 PolarHBondContact N-OD1 2.8Å; R373-N453 PolarHBondContact O-N 3.11Å; R373-N453 PolarHBondContact O-OD1 3.42Å; R373-L454 PolarHBondContact O-N 2.86Å
374G94.1Very high88.3Confident0 Ų048.9 Ų48.90%026%0.26CS..EExtended strand (participates in β ladder)trans-115.3148-173.800000113.2F429 N435 L436 L437 L454G374-F429 WeakPolarHBondContact O-CZ 3.42Å; G374-N435 PolarHBondContact N-O 3.38Å; G374-L436 WeakPolarHBondContact O-CA 3.26Å; G374-L437 PolarHBondContact O-N 3.42Å; G374-L454 CarbonylContact C-O 3.57Å; G374-L454 VanDerWaalsContact CA-O 3.24Å; G374-L454 WeakPolarHBondContact CA-O 3Å
375I95Very high88.3Confident1 Ų151.1 Ų51.11%0.00525%0.25CS..EExtended strand (participates in β ladder)trans-120.4119.2165.2-53.7177.3000108.9F377 F429 L437 L447 I449 L454 V455 V456 R473I375-F377 HydrophobicContact CB-CE2 4.2Å; I375-F377 HydrophobicContact CG2-CD1 4.28Å; I375-F377 HydrophobicContact CG2-CD2 3.91Å; I375-F377 HydrophobicContact CG2-CE1 3.94Å; I375-F377 HydrophobicContact CG2-CE2 3.53Å; I375-F377 HydrophobicContact CG2-CG 4.27Å; I375-F377 HydrophobicContact CG2-CZ 3.55Å; I375-F429 HydrophobicContact CG1-CZ 4.45Å; I375-L437 CarbonylContact C-O 3.57Å; I375-L437 WeakPolarHBondContact CA-O 3.22Å; I375-L437 HydrophobicContact CG1-CB 4.39Å; I375-L437 HydrophobicContact CG2-CB 4.43Å; I375-L447 HydrophobicContact CD1-CD2 4.43Å; I375-I449 HydrophobicContact CD1-CD1 4.37Å; I375-L454 PolarHBondContact N-O 3.36Å; I375-V455 CarbonylContact O-C 3.52Å; I375-V455 WeakPolarHBondContact O-CA 3.25Å; I375-V456 PolarHBondContact O-N 2.84Å; I375-R473 HydrophobicContact CD1-CB 3.96Å; I375-R473 HydrophobicContact CD1-CG 4.36Å
376L95.3Very high88.4Confident0 Ų049.7 Ų49.70%024%0.244CC..EExtended strand (participates in β ladder)trans-100.2106.5173.2173.758.5000109.1L358 L387 L436 L437 I438 S439 V456 Y458L358-L376 HydrophobicContact CD1-CD1 3.77Å; L358-L376 HydrophobicContact CD1-CD2 4.33Å; L358-L376 HydrophobicContact CD2-CD1 4.34Å; L358-L376 HydrophobicContact CD2-CD2 3.99Å; L376-L387 HydrophobicContact CD2-CB 4.48Å; L376-L387 HydrophobicContact CD2-CD1 4.01Å; L376-L387 HydrophobicContact CD2-CD2 4.3Å; L376-L387 HydrophobicContact CG-CD1 4.34Å; L376-L436 HydrophobicContact CB-CD1 4.21Å; L376-L437 PolarHBondContact N-O 2.92Å; L376-I438 HydrophobicContact CB-CG1 4.48Å; L376-I438 HydrophobicContact CD2-CG1 4.33Å; L376-I438 HydrophobicContact CD2-CG2 4.4Å; L376-I438 CarbonylContact O-C 3.49Å; L376-I438 WeakPolarHBondContact O-CA 3.37Å; L376-S439 PolarHBondContact O-N 3.15Å; L376-V456 HydrophobicContact CD1-CB 3.79Å; L376-V456 HydrophobicContact CD1-CG1 3.79Å; L376-Y458 HydrophobicContact CD1-CG 4.35Å
377F93.1Very high88.5Confident0 Ų049.3 Ų49.30%024%0.243CC..EExtended strand (participates in β ladder)trans-86.7131.1177.2-70.3-75.6000111.7I375 S439 T440 A443 E444 V455 V456 Y458 L460 A470I375-F377 HydrophobicContact CB-CE2 4.2Å; I375-F377 HydrophobicContact CG2-CD1 4.28Å; I375-F377 HydrophobicContact CG2-CD2 3.91Å; I375-F377 HydrophobicContact CG2-CE1 3.94Å; I375-F377 HydrophobicContact CG2-CE2 3.53Å; I375-F377 HydrophobicContact CG2-CG 4.27Å; I375-F377 HydrophobicContact CG2-CZ 3.55Å; F377-S439 CarbonylContact C-O 3.6Å; F377-S439 VanDerWaalsContact CA-O 3.3Å; F377-S439 WeakPolarHBondContact CA-O 3.44Å; F377-T440 WeakPolarHBondContact CD1-O 3.36Å; F377-A443 HydrophobicContact CE1-CB 3.78Å; F377-A443 HydrophobicContact CZ-CB 4.11Å; F377-E444 HydrophobicContact CD1-CG 3.87Å; F377-E444 HydrophobicContact CE1-CB 4.3Å; F377-E444 HydrophobicContact CE1-CG 3.51Å; F377-E444 HydrophobicContact CZ-CB 4.44Å; F377-E444 HydrophobicContact CZ-CG 3.89Å; F377-V455 HydrophobicContact CD2-CG1 3.87Å; F377-V455 HydrophobicContact CE2-CG1 3.86Å; F377-V456 PolarHBondContact N-O 3.38Å; F377-Y458 PolarHBondContact O-N 2.94Å; F377-L460 HydrophobicContact CB-CD1 3.44Å; F377-L460 VanDerWaalsContact CB-CD1 3.44Å; F377-A470 HydrophobicContact CD2-CB 4.21Å; F377-A470 HydrophobicContact CE2-CB 3.88Å; F377-A470 HydrophobicContact CZ-CB 4.46Å
378S89.8Confident88.9Confident3 Ų350 Ų502%0.02124%0.243CC..  trans-134.1153.5174.9-167.60000111.6S383 S439 T440S378-S383 WeakPolarHBondContact OG-CB 3.46Å; S378-S439 PolarHBondContact N-O 2.82Å; S378-T440 WeakPolarHBondContact O-CA 3.19Å
379R83.4Confident89.6Confident127 Ų12746.7 Ų46.748%0.47922%0.22SC..SBendtrans-69.1-43.3-168-173.5179.6177.9-157.80113.2Q261 L460Q261-R379 VanDerWaalsContact NE2-CZ 3.32Å; R379-L460 HydrophobicContact CB-CD2 3.81Å; R379-L460 VanDerWaalsContact N-CD2 3.34Å
380T84.9Confident90.3Very high55 Ų5539.6 Ų39.634%0.33718%0.181SC..SBendtrans-119151.4-168.583.10000111.6R382 S383 T384T380-R382 PolarHBondContact O-N 2.9Å; T380-R382 PolarHBondContact OG1-N 3.42Å; T380-S383 WeakPolarHBondContact O-CB 3.21Å; T380-S383 PolarHBondContact O-N 2.88Å; T380-S383 VanDerWaalsContact O-N 3.11Å; T380-S383 WeakPolarHBondContact OG1-CB 3.43Å; T380-S383 PolarHBondContact OG1-N 3.05Å; T380-S383 PolarHBondContact OG1-OG 3.44Å; T380-T384 PolarHBondContact O-N 3.28Å
381R85.7Confident90.9Very high67 Ų6736 Ų3625%0.25316%0.159SC..Hα-helixtrans-58.3-37.7174.1-60.7-177.5-178.5161.2-6111.7T384 R385 T408 G409 T440R381-T384 PolarHBondContact O-N 3.2Å; R381-T384 PolarHBondContact O-OG1 3.37Å; R381-R385 PolarHBondContact O-N 2.76Å; R381-T408 HydrophobicContact CB-CG2 4.24Å; R381-T408 HydrophobicContact CG-CG2 3.92Å; R381-G409 PolarHBondContact NH2-O 3.33Å; R381-T440 HydrophobicContact CG-CG2 4.33Å
382R85.6Confident91.4Very high72 Ų7232.4 Ų32.427%0.27214%0.142SC..Hα-helixtrans-60.1-49.1174.5-172.5-177-174.9106.637.7110.8S310 E313 T380 T384 R385 C386S310-R382 PolarHBondContact OG-NE 2.93Å; S310-R382 PolarHBondContact OG-NH1 2.82Å; E313-R382 IonicContact OE1-NH2 3.53Å; E313-R382 IonicContact OE2-CZ 3.38Å; E313-R382 IonicContact OE2-NH1 3.58Å; E313-R382 IonicContact OE2-NH2 2.81Å; E313-R382 PolarHBondContact OE2-NH2 2.97Å; T380-R382 PolarHBondContact O-N 2.9Å; T380-R382 PolarHBondContact OG1-N 3.42Å; R382-T384 VanDerWaalsContact C-N 3.29Å; R382-T384 PolarHBondContact O-N 3.12Å; R382-R385 WeakPolarHBondContact O-CB 3.43Å; R382-R385 PolarHBondContact O-N 3.47Å; R382-C386 PolarHBondContact O-N 2.96Å; R382-C386 PolarHBondContact O-SG 3.03Å
383S89.3Confident91.6Very high9 Ų938 Ų386%0.06317%0.166CC..Hα-helixtrans-59.1-39.7178.3-55.20000112.3S378 T380 R385 C386 L387S378-S383 WeakPolarHBondContact OG-CB 3.46Å; T380-S383 WeakPolarHBondContact O-CB 3.21Å; T380-S383 PolarHBondContact O-N 2.88Å; T380-S383 VanDerWaalsContact O-N 3.11Å; T380-S383 WeakPolarHBondContact OG1-CB 3.43Å; T380-S383 PolarHBondContact OG1-N 3.05Å; T380-S383 PolarHBondContact OG1-OG 3.44Å; S383-R385 VanDerWaalsContact C-N 3.28Å; S383-R385 PolarHBondContact O-N 2.66Å; S383-C386 PolarHBondContact O-N 3.5Å; S383-L387 WeakPolarHBondContact O-CB 3.24Å; S383-L387 VanDerWaalsContact O-CG 3.3Å; S383-L387 WeakPolarHBondContact O-CG 3.43Å; S383-L387 PolarHBondContact O-N 3.4Å
384T91.9Very high91.7Very high0 Ų037.4 Ų37.40%017%0.166CC..Hα-helixtrans-61.7-34.3175.760.20000113.1T380 R381 R382 L388 T408 I438 T440T380-T384 PolarHBondContact O-N 3.28Å; R381-T384 PolarHBondContact O-N 3.2Å; R381-T384 PolarHBondContact O-OG1 3.37Å; R382-T384 VanDerWaalsContact C-N 3.29Å; R382-T384 PolarHBondContact O-N 3.12Å; T384-L388 WeakPolarHBondContact O-CB 3.36Å; T384-L388 PolarHBondContact O-N 2.78Å; T384-T408 HydrophobicContact CG2-CG2 4.45Å; T384-I438 HydrophobicContact CG2-CG2 4.07Å; T384-T440 HydrophobicContact CG2-CG2 3.9Å
385R90.6Very high91.7Very high109 Ų10946.9 Ų46.941%0.41120%0.201SC..Hα-helixtrans-72.4-44.2176.1-68.1171.2170.4-156.8-12.8112.8R381 R382 S383 L387 L388 D389 I406 I414 T415R381-R385 PolarHBondContact O-N 2.76Å; R382-R385 WeakPolarHBondContact O-CB 3.43Å; R382-R385 PolarHBondContact O-N 3.47Å; S383-R385 VanDerWaalsContact C-N 3.28Å; S383-R385 PolarHBondContact O-N 2.66Å; R385-L387 VanDerWaalsContact C-N 3.29Å; R385-L387 PolarHBondContact O-N 3.37Å; R385-L388 PolarHBondContact O-N 3.18Å; R385-D389 WeakPolarHBondContact O-CB 3.27Å; R385-D389 PolarHBondContact O-N 3.44Å; R385-I406 HydrophobicContact CB-CD1 4.16Å; R385-I406 HydrophobicContact CG-CD1 3.58Å; R385-I414 PolarHBondContact NH2-O 3.03Å; R385-I414 VanDerWaalsContact NH2-O 3.1Å; R385-T415 VanDerWaalsContact NH2-CB 3.28Å
386C91.7Very high91.7Very high13 Ų1350 Ų509%0.08822%0.221CC..Hα-helixtrans-59.1-42.9174.5-67.10000111.3L302 R303 D306 R382 S383 D389 W390L302-C386 HydrophobicContact CD1-CB 3.69Å; R303-C386 PolarHBondContact NH2-O 2.76Å; D306-C386 HydrophobicContact CB-CB 4.07Å; R382-C386 PolarHBondContact O-N 2.96Å; R382-C386 PolarHBondContact O-SG 3.03Å; S383-C386 PolarHBondContact O-N 3.5Å; C386-D389 PolarHBondContact O-N 2.96Å; C386-W390 WeakPolarHBondContact O-CB 3.13Å; C386-W390 PolarHBondContact O-N 3.2Å
387L94.4Very high91.7Very high0 Ų050 Ų500%022%0.221CC..Hα-helixtrans-64.7-41.7174.8-73168.6000112L302 M355 L358 L376 S383 R385 W390 V391 I438 Y458L302-L387 HydrophobicContact CD2-CD1 4.25Å; L302-L387 HydrophobicContact CD2-CD2 3.47Å; L302-L387 VanDerWaalsContact CD2-CD2 3.47Å; L302-L387 HydrophobicContact CD2-CG 3.61Å; M355-L387 HydrophobicContact CE-CD2 4.41Å; M355-L387 HydrophobicContact SD-CD2 4.39Å; L358-L387 HydrophobicContact CD2-CD2 3.87Å; L376-L387 HydrophobicContact CD2-CB 4.48Å; L376-L387 HydrophobicContact CD2-CD1 4.01Å; L376-L387 HydrophobicContact CD2-CD2 4.3Å; L376-L387 HydrophobicContact CG-CD1 4.34Å; S383-L387 WeakPolarHBondContact O-CB 3.24Å; S383-L387 VanDerWaalsContact O-CG 3.3Å; S383-L387 WeakPolarHBondContact O-CG 3.43Å; S383-L387 PolarHBondContact O-N 3.4Å; R385-L387 VanDerWaalsContact C-N 3.29Å; R385-L387 PolarHBondContact O-N 3.37Å; L387-W390 HydrophobicContact CD2-CE3 4.38Å; L387-W390 PolarHBondContact O-N 3.24Å; L387-V391 WeakPolarHBondContact O-CG2 3.19Å; L387-V391 PolarHBondContact O-N 3.1Å; L387-I438 HydrophobicContact CB-CD1 4.15Å; L387-I438 HydrophobicContact CB-CG2 3.86Å; L387-I438 HydrophobicContact CD1-CG2 4.08Å; L387-Y458 HydrophobicContact CD1-CD1 4.47Å; L387-Y458 HydrophobicContact CD2-CE1 4.36Å
388L95.3Very high91.7Very high29 Ų2955 Ų5515%0.15224%0.244CC..Hα-helixtrans-61.5-47.8175-178.466.6000111.5T384 R385 W390 V391 Q392 A404 I406 I438T384-L388 WeakPolarHBondContact O-CB 3.36Å; T384-L388 PolarHBondContact O-N 2.78Å; R385-L388 PolarHBondContact O-N 3.18Å; L388-W390 VanDerWaalsContact C-N 3.27Å; L388-W390 PolarHBondContact O-N 3.02Å; L388-V391 PolarHBondContact O-N 2.75Å; L388-Q392 HydrophobicContact CD1-CG 4.1Å; L388-Q392 HydrophobicContact CG-CG 4.28Å; L388-Q392 WeakPolarHBondContact O-CB 3.4Å; L388-Q392 VanDerWaalsContact O-CG 3.29Å; L388-Q392 WeakPolarHBondContact O-CG 3.43Å; L388-Q392 PolarHBondContact O-N 3.06Å; L388-A404 HydrophobicContact CD1-CB 3.83Å; L388-A404 WeakPolarHBondContact CD1-O 3.28Å; L388-I406 HydrophobicContact CB-CD1 3.87Å; L388-I406 HydrophobicContact CB-CG1 3.92Å; L388-I406 HydrophobicContact CD2-CD1 3.63Å; L388-I406 HydrophobicContact CD2-CG1 3.83Å; L388-I406 HydrophobicContact CG-CD1 4.36Å; L388-I406 HydrophobicContact CG-CG1 4.36Å; L388-I438 HydrophobicContact CB-CD1 4.03Å; L388-I438 HydrophobicContact CD1-CD1 4.2Å
389D94.4Very high91.9Very high35 Ų3563 Ų6319%0.18728%0.278CS..Hα-helixtrans-57.6-41.8176.2179.373.6000111.5R303 R309 R385 C386 K393R303-D389 IonicContact CZ-OD2 3.41Å; R303-D389 IonicContact NH1-OD2 3.6Å; R303-D389 PolarHBondContact NH1-OD2 3.42Å; R303-D389 IonicContact NH2-OD2 2.69Å; R303-D389 PolarHBondContact NH2-OD2 3.06Å; R309-D389 IonicContact NH1-OD2 3.38Å; R309-D389 PolarHBondContact NH1-OD2 3.34Å; R385-D389 WeakPolarHBondContact O-CB 3.27Å; R385-D389 PolarHBondContact O-N 3.44Å; C386-D389 PolarHBondContact O-N 2.96Å; D389-K393 WeakPolarHBondContact O-CB 3.41Å; D389-K393 WeakPolarHBondContact O-CG 3.12Å; D389-K393 PolarHBondContact O-N 2.82Å; D389-K393 VanDerWaalsContact O-N 3.08Å; D389-K393 WeakPolarHBondContact OD1-CE 3.21Å; D389-K393 IonicContact OD1-NZ 3.94Å; D389-K393 PolarHBondContact OD1-NZ 3.21Å; D389-K393 IonicContact OD2-NZ 3.28Å; D389-K393 PolarHBondContact OD2-NZ 3.02Å
390W94.3Very high92.4Very high13 Ų1357.4 Ų57.45%0.04926%0.259CS..Hα-helixtrans-63.4-50.917517072.6000112.4M355 L358 E359 L362 C386 L387 L388 Q392 K393 N394 L397M355-W390 HydrophobicContact CE-CB 4.06Å; M355-W390 HydrophobicContact CE-CD2 3.25Å; M355-W390 VanDerWaalsContact CE-CE2 3.42Å; M355-W390 HydrophobicContact CE-CE3 3.81Å; M355-W390 HydrophobicContact CE-CG 3.33Å; M355-W390 HydrophobicContact CE-CZ2 4.07Å; M355-W390 HydrophobicContact CE-CZ3 4.42Å; L358-W390 HydrophobicContact CB-CH2 4.4Å; L358-W390 HydrophobicContact CD2-CE3 4.45Å; L358-W390 HydrophobicContact CD2-CH2 3.99Å; L358-W390 HydrophobicContact CD2-CZ3 3.65Å; L358-W390 HydrophobicContact CG-CH2 3.93Å; L358-W390 HydrophobicContact CG-CZ3 4.01Å; E359-W390 HydrophobicContact CB-CH2 4.16Å; E359-W390 HydrophobicContact CB-CZ2 3.92Å; E359-W390 HydrophobicContact CG-CZ2 4.48Å; L362-W390 HydrophobicContact CD1-CH2 4.16Å; L362-W390 HydrophobicContact CD1-CZ3 4.02Å; C386-W390 WeakPolarHBondContact O-CB 3.13Å; C386-W390 PolarHBondContact O-N 3.2Å; L387-W390 HydrophobicContact CD2-CE3 4.38Å; L387-W390 PolarHBondContact O-N 3.24Å; L388-W390 VanDerWaalsContact C-N 3.27Å; L388-W390 PolarHBondContact O-N 3.02Å; W390-Q392 VanDerWaalsContact C-N 3.31Å; W390-Q392 PolarHBondContact O-N 3.35Å; W390-K393 PolarHBondContact O-N 3.03Å; W390-K393 VanDerWaalsContact O-N 3.16Å; W390-N394 WeakPolarHBondContact O-CB 3.46Å; W390-N394 PolarHBondContact O-N 3.3Å; W390-L397 HydrophobicContact CE3-CD1 4.34Å; W390-L397 HydrophobicContact CH2-CD1 3.61Å; W390-L397 HydrophobicContact CZ2-CD1 3.95Å; W390-L397 HydrophobicContact CZ3-CD1 3.81Å
391V95.4Very high92.8Very high4 Ų456.2 Ų56.22%0.02426%0.258CS..Hα-helixtrans-58.6-45178.3172.40000110.7L387 L388 K393 N394 L397 I402 A404 L436 I438L387-V391 WeakPolarHBondContact O-CG2 3.19Å; L387-V391 PolarHBondContact O-N 3.1Å; L388-V391 PolarHBondContact O-N 2.75Å; V391-K393 VanDerWaalsContact C-N 3.27Å; V391-K393 PolarHBondContact O-N 3.16Å; V391-N394 PolarHBondContact O-N 3.29Å; V391-L397 HydrophobicContact CB-CD1 4.43Å; V391-L397 HydrophobicContact CG1-CD1 4.39Å; V391-L397 HydrophobicContact CG2-CD1 4.13Å; V391-I402 HydrophobicContact CG1-CG2 3.79Å; V391-A404 HydrophobicContact CB-CB 4.44Å; V391-A404 HydrophobicContact CG1-CB 3.81Å; V391-L436 HydrophobicContact CG1-CD2 4.44Å; V391-L436 HydrophobicContact CG2-CD2 4.22Å; V391-I438 HydrophobicContact CG2-CD1 4.11Å
392Q94.4Very high93.2Very high107 Ų10753.7 Ų53.750%0.525%0.249SC..Hα-helixtrans-67.9-23-179.3-73.9179.2-18.800113.5L388 W390 Q398L388-Q392 HydrophobicContact CD1-CG 4.1Å; L388-Q392 HydrophobicContact CG-CG 4.28Å; L388-Q392 WeakPolarHBondContact O-CB 3.4Å; L388-Q392 VanDerWaalsContact O-CG 3.29Å; L388-Q392 WeakPolarHBondContact O-CG 3.43Å; L388-Q392 PolarHBondContact O-N 3.06Å; W390-Q392 VanDerWaalsContact C-N 3.31Å; W390-Q392 PolarHBondContact O-N 3.35Å; Q392-Q398 PolarHBondContact O-NE2 3.34Å
393K93.7Very high93.7Very high120 Ų12056.2 Ų56.252%0.52226%0.262SS..Hα-helixtrans-97.6-15.6178-72.6173176.3164.10113.5D389 W390 V391 R395D389-K393 WeakPolarHBondContact O-CB 3.41Å; D389-K393 WeakPolarHBondContact O-CG 3.12Å; D389-K393 PolarHBondContact O-N 2.82Å; D389-K393 VanDerWaalsContact O-N 3.08Å; D389-K393 WeakPolarHBondContact OD1-CE 3.21Å; D389-K393 IonicContact OD1-NZ 3.94Å; D389-K393 PolarHBondContact OD1-NZ 3.21Å; D389-K393 IonicContact OD2-NZ 3.28Å; D389-K393 PolarHBondContact OD2-NZ 3.02Å; W390-K393 PolarHBondContact O-N 3.03Å; W390-K393 VanDerWaalsContact O-N 3.16Å; V391-K393 VanDerWaalsContact C-N 3.27Å; V391-K393 PolarHBondContact O-N 3.16Å; K393-R395 PolarHBondContact O-N 3.25Å
394N94.1Very high94Very high21 Ų2156.5 Ų56.511%0.11227%0.266CS..  trans-79.4111.1-179.9-173.9-43.4000111.1E359 W390 V391 T396 L397 Q398E359-N394 PolarHBondContact OE1-ND2 2.97Å; E359-N394 PolarHBondContact OE1-OD1 2.73Å; E359-N394 PolarHBondContact OE2-ND2 3.41Å; E359-N394 VanDerWaalsContact OE2-ND2 3.08Å; W390-N394 WeakPolarHBondContact O-CB 3.46Å; W390-N394 PolarHBondContact O-N 3.3Å; V391-N394 PolarHBondContact O-N 3.29Å; N394-T396 VanDerWaalsContact C-N 3.31Å; N394-T396 PolarHBondContact O-N 2.84Å; N394-T396 WeakPolarHBondContact OD1-CA 3.42Å; N394-T396 WeakPolarHBondContact OD1-CB 3.17Å; N394-T396 PolarHBondContact OD1-N 2.89Å; N394-T396 PolarHBondContact OD1-OG1 3.37Å; N394-L397 HydrophobicContact CB-CB 4.17Å; N394-L397 HydrophobicContact CB-CD1 3.91Å; N394-L397 HydrophobicContact CB-CG 4.03Å; N394-L397 PolarHBondContact O-N 3.2Å; N394-L397 PolarHBondContact OD1-N 2.91Å; N394-L397 VanDerWaalsContact OD1-N 3.13Å; N394-Q398 WeakPolarHBondContact O-CG 3.11Å; N394-Q398 PolarHBondContact O-N 3Å
395R94.2Very high94.2Very high199 Ų19957.4 Ų57.475%0.75127%0.273SS*.Hα-helixtrans-63.9-31.5-178.8-68.4-174.5178.3-173.1-0.5113.5K393 K399K393-R395 PolarHBondContact O-N 3.25Å; R395-K399 WeakPolarHBondContact O-CB 3.33Å; R395-K399 VanDerWaalsContact O-CG 3.28Å; R395-K399 WeakPolarHBondContact O-CG 3.22Å; R395-K399 PolarHBondContact O-N 2.96Å
396T94.8Very high94.3Very high68 Ų6853.5 Ų53.542%0.41726%0.26SS..Hα-helixtrans-69.3-45.2179.6-41.10000110.4E359 L363 N394 Q398 K399 A400E359-T396 WeakPolarHBondContact OE1-CB 3.18Å; E359-T396 PolarHBondContact OE1-OG1 3.12Å; L363-T396 HydrophobicContact CD1-CG2 3.56Å; L363-T396 HydrophobicContact CD2-CG2 3.98Å; L363-T396 HydrophobicContact CG-CG2 4.43Å; N394-T396 VanDerWaalsContact C-N 3.31Å; N394-T396 PolarHBondContact O-N 2.84Å; N394-T396 WeakPolarHBondContact OD1-CA 3.42Å; N394-T396 WeakPolarHBondContact OD1-CB 3.17Å; N394-T396 PolarHBondContact OD1-N 2.89Å; N394-T396 PolarHBondContact OD1-OG1 3.37Å; T396-Q398 PolarHBondContact O-N 2.92Å; T396-K399 PolarHBondContact O-N 2.76Å; T396-A400 PolarHBondContact O-N 2.86Å
397L94.9Very high94.3Very high0 Ų053 Ų530%026%0.257CS..Hα-helixtrans-64.8-38.9175.9-63-178.4000112.1E359 L362 L363 W390 V391 N394 A400 G401 I402E359-L397 HydrophobicContact CG-CD2 4.1Å; E359-L397 HydrophobicContact CG-CG 4.43Å; L362-L397 HydrophobicContact CB-CD2 3.93Å; L362-L397 HydrophobicContact CD1-CD1 4.16Å; L362-L397 HydrophobicContact CD1-CD2 4.19Å; L363-L397 HydrophobicContact CD2-CD2 3.9Å; L363-L397 HydrophobicContact CG-CD2 3.94Å; W390-L397 HydrophobicContact CE3-CD1 4.34Å; W390-L397 HydrophobicContact CH2-CD1 3.61Å; W390-L397 HydrophobicContact CZ2-CD1 3.95Å; W390-L397 HydrophobicContact CZ3-CD1 3.81Å; V391-L397 HydrophobicContact CB-CD1 4.43Å; V391-L397 HydrophobicContact CG1-CD1 4.39Å; V391-L397 HydrophobicContact CG2-CD1 4.13Å; N394-L397 HydrophobicContact CB-CB 4.17Å; N394-L397 HydrophobicContact CB-CD1 3.91Å; N394-L397 HydrophobicContact CB-CG 4.03Å; N394-L397 PolarHBondContact O-N 3.2Å; N394-L397 PolarHBondContact OD1-N 2.91Å; N394-L397 VanDerWaalsContact OD1-N 3.13Å; L397-A400 PolarHBondContact O-N 2.86Å; L397-G401 PolarHBondContact O-N 3.23Å; L397-I402 HydrophobicContact CB-CD1 4.09Å; L397-I402 HydrophobicContact CD2-CD1 3.75Å; L397-I402 HydrophobicContact CG-CD1 4.42Å; L397-I402 WeakPolarHBondContact O-CB 3.32Å; L397-I402 PolarHBondContact O-N 2.97Å
398Q93.6Very high93.9Very high105 Ų10553.2 Ų53.249%0.49126%0.257SS..Hα-helixtrans-61-45.1172.7-72176.8-2.200112.1Q392 N394 T396 A400 G401Q392-Q398 PolarHBondContact O-NE2 3.34Å; N394-Q398 WeakPolarHBondContact O-CG 3.11Å; N394-Q398 PolarHBondContact O-N 3Å; T396-Q398 PolarHBondContact O-N 2.92Å; Q398-A400 PolarHBondContact O-N 3.04Å; Q398-G401 PolarHBondContact O-N 3.25Å
399K93.3Very high93Very high170 Ų17052.5 Ų52.574%0.73926%0.257SS*.Hα-helixtrans-63.8-30.4177-76.5176.4179.5-174.90112.7R395 T396 G401R395-K399 WeakPolarHBondContact O-CB 3.33Å; R395-K399 VanDerWaalsContact O-CG 3.28Å; R395-K399 WeakPolarHBondContact O-CG 3.22Å; R395-K399 PolarHBondContact O-N 2.96Å; T396-K399 PolarHBondContact O-N 2.76Å; K399-G401 PolarHBondContact O-N 2.91Å
400A93.4Very high91.6Very high9 Ų953.8 Ų53.87%0.07427%0.273CS..THydrogen-bonded Turntrans-742.4172.200000113.6L363 F366 G367 T396 L397 Q398 I402L363-A400 HydrophobicContact CD2-CB 3.62Å; F366-A400 HydrophobicContact CB-CB 4.39Å; G367-A400 CarbonylContact C-O 3.53Å; T396-A400 PolarHBondContact O-N 2.86Å; L397-A400 PolarHBondContact O-N 2.86Å; Q398-A400 PolarHBondContact O-N 3.04Å; A400-I402 HydrophobicContact CB-CG1 4.44Å
401G93.2Very high89.9Confident30 Ų3054.2 Ų54.231%0.30928%0.282SS..THydrogen-bonded Turntrans80.116.317600000114.4L397 Q398 K399 K403 N435L397-G401 PolarHBondContact O-N 3.23Å; Q398-G401 PolarHBondContact O-N 3.25Å; K399-G401 PolarHBondContact O-N 2.91Å; G401-K403 PolarHBondContact O-N 2.83Å; G401-N435 PolarHBondContact O-ND2 2.88Å
402I95.3Very high87.6Confident15 Ų1562 Ų628%0.07732%0.323CS..  trans-72.3123-177.7-60.9-178.1000110.9L362 F366 V391 L397 A400 A404 N435 L436L362-I402 HydrophobicContact CB-CD1 4.12Å; F366-I402 HydrophobicContact CB-CD1 3.89Å; F366-I402 HydrophobicContact CB-CG1 3.8Å; F366-I402 HydrophobicContact CD1-CD1 4.4Å; F366-I402 HydrophobicContact CD1-CG1 3.85Å; F366-I402 HydrophobicContact CD2-CD1 3.94Å; F366-I402 HydrophobicContact CD2-CG1 4.29Å; F366-I402 HydrophobicContact CE1-CG1 4.48Å; F366-I402 HydrophobicContact CG-CD1 3.83Å; F366-I402 HydrophobicContact CG-CG1 3.73Å; V391-I402 HydrophobicContact CG1-CG2 3.79Å; L397-I402 HydrophobicContact CB-CD1 4.09Å; L397-I402 HydrophobicContact CD2-CD1 3.75Å; L397-I402 HydrophobicContact CG-CD1 4.42Å; L397-I402 WeakPolarHBondContact O-CB 3.32Å; L397-I402 PolarHBondContact O-N 2.97Å; A400-I402 HydrophobicContact CB-CG1 4.44Å; I402-A404 HydrophobicContact CG2-CB 4.42Å; I402-N435 WeakPolarHBondContact CA-OD1 3.4Å; I402-L436 HydrophobicContact CG2-CB 3.83Å; I402-L436 HydrophobicContact CG2-CD2 3.7Å; I402-L436 HydrophobicContact CG2-CG 4.43Å
403K95Very high85.4Confident124 Ų12459 Ų5954%0.53932%0.32SS..  trans-119.399.1175.3-63.5175.7-172.4173.50108.2G401 I433 N435 L436G401-K403 PolarHBondContact O-N 2.83Å; K403-I433 WeakPolarHBondContact CD-O 3.38Å; K403-N435 PolarHBondContact N-OD1 3.17Å; K403-N435 PolarHBondContact O-N 2.91Å; K403-N435 PolarHBondContact O-OD1 3.4Å; K403-L436 PolarHBondContact O-N 3.28Å
404A96.2Very high82.9Confident16 Ų1661.2 Ų61.213%0.13234%0.336CS..EExtended strand (participates in β ladder)trans-102.4147-172.200000113.3L388 V391 I402 L436 I438L388-A404 HydrophobicContact CD1-CB 3.83Å; L388-A404 WeakPolarHBondContact CD1-O 3.28Å; V391-A404 HydrophobicContact CB-CB 4.44Å; V391-A404 HydrophobicContact CG1-CB 3.81Å; I402-A404 HydrophobicContact CG2-CB 4.42Å; A404-L436 VanDerWaalsContact CA-O 3.23Å; A404-L436 WeakPolarHBondContact CA-O 3.38Å; A404-L436 HydrophobicContact CB-CB 4.04Å; A404-L436 HydrophobicContact CB-CD2 4.1Å; A404-L436 HydrophobicContact CB-CG 4.26Å; A404-I438 HydrophobicContact CB-CD1 4.16Å
405A95.6Very high81Confident19 Ų1962.3 Ų62.316%0.15734%0.344CS..EExtended strand (participates in β ladder)trans-140.7160.5166.100000111T425 L434 L436 I438A405-T425 HydrophobicContact CB-CG2 4.03Å; A405-L434 HydrophobicContact CB-CD1 3.52Å; A405-L434 HydrophobicContact CB-CD2 3.96Å; A405-L434 HydrophobicContact CB-CG 4.35Å; A405-L436 PolarHBondContact N-O 2.88Å; A405-L436 VanDerWaalsContact N-O 3.12Å; A405-I438 PolarHBondContact O-N 2.83Å
406I94Very high79.8Confident27 Ų2756.6 Ų56.614%0.13832%0.323CS..EExtended strand (participates in β ladder)trans-85.8146.5177.1-68.8164.6000110R385 L388 T408 M417 I438R385-I406 HydrophobicContact CB-CD1 4.16Å; R385-I406 HydrophobicContact CG-CD1 3.58Å; L388-I406 HydrophobicContact CB-CD1 3.87Å; L388-I406 HydrophobicContact CB-CG1 3.92Å; L388-I406 HydrophobicContact CD2-CD1 3.63Å; L388-I406 HydrophobicContact CD2-CG1 3.83Å; L388-I406 HydrophobicContact CG-CD1 4.36Å; L388-I406 HydrophobicContact CG-CG1 4.36Å; I406-T408 HydrophobicContact CG2-CG2 3.4Å; I406-T408 VanDerWaalsContact CG2-CG2 3.4Å; I406-M417 HydrophobicContact CG2-SD 4.11Å; I406-M417 WeakPolarHBondContact O-CE 3.49Å; I406-I438 CarbonylContact C-O 3.57Å; I406-I438 VanDerWaalsContact CA-O 3.25Å; I406-I438 WeakPolarHBondContact CA-O 3.21Å
407L90.5Very high78.8Confident3 Ų354.4 Ų54.42%0.01631%0.308CS..EExtended strand (participates in β ladder)trans-129.7105.8166.2-174.859.1000110.3M417 Q422 I426 L437 I438 S439 T440 A443 L447L407-M417 VanDerWaalsContact CA-SD 3.59Å; L407-M417 HydrophobicContact CD1-CE 4.38Å; L407-Q422 HydrophobicContact CD1-CB 3.95Å; L407-Q422 HydrophobicContact CD1-CG 3.85Å; L407-I426 HydrophobicContact CD1-CD1 4.36Å; L407-I426 HydrophobicContact CD1-CG1 4.25Å; L407-I426 HydrophobicContact CD2-CD1 4.25Å; L407-I426 HydrophobicContact CD2-CG1 3.9Å; L407-L437 HydrophobicContact CD2-CD1 4.14Å; L407-I438 PolarHBondContact N-O 3.49Å; L407-S439 VanDerWaalsContact O-CA 3.24Å; L407-S439 WeakPolarHBondContact O-CA 3.41Å; L407-S439 PolarHBondContact O-OG 3.23Å; L407-S439 VanDerWaalsContact O-OG 3.07Å; L407-T440 PolarHBondContact O-N 3.36Å; L407-A443 HydrophobicContact CD2-CB 3.91Å; L407-L447 HydrophobicContact CD2-CD2 4.17Å
408T87.1Confident77.7Confident3 Ų355 Ų552%0.01831%0.312CS..  trans-126.7161-179.562.90000111.2R381 T384 I406 M417 Q422 T440R381-T408 HydrophobicContact CB-CG2 4.24Å; R381-T408 HydrophobicContact CG-CG2 3.92Å; T384-T408 HydrophobicContact CG2-CG2 4.45Å; I406-T408 HydrophobicContact CG2-CG2 3.4Å; I406-T408 VanDerWaalsContact CG2-CG2 3.4Å; T408-M417 PolarHBondContact N-SD 3.11Å; T408-Q422 VanDerWaalsContact O-CD 3.31Å; T408-Q422 PolarHBondContact O-NE2 2.84Å; T408-T440 HydrophobicContact CG2-CG2 4.03Å
409G75.4Confident76.7Confident14 Ų1452.5 Ų52.514%0.14430%0.3CS..  trans-79150.5-175.500000113.4R381 G411R381-G409 PolarHBondContact NH2-O 3.33Å; G409-G411 PolarHBondContact O-N 2.66Å
410A65Low75.8Confident62 Ų6249.6 Ų49.651%0.51229%0.293SS..  trans-62.7120.317100000110.3M417A410-M417 WeakPolarHBondContact CA-O 3.26Å
411G58.6Low75.3Confident23 Ų2353.2 Ų53.224%0.23731%0.308CS..  trans-171.9167.4173.400000110.7G409 Y416G409-G411 PolarHBondContact O-N 2.66Å; G411-Y416 WeakPolarHBondContact O-CB 3.46Å; G411-Y416 WeakPolarHBondContact O-CD1 3.23Å
412N46.4Very low74.8Confident167 Ų16752.6 Ų52.689%0.89330%0.297SS*.SBendtrans-78.5134.2-165.2-56.6-4.9000112.9
413G48.6Very low74.1Confident43 Ų4354.1 Ų54.144%0.44331%0.312SS..SBendtrans147.5177.4174.900000113.9T415 Y416G413-T415 PolarHBondContact O-N 3.33Å; G413-Y416 WeakPolarHBondContact O-CD1 3.45Å; G413-Y416 WeakPolarHBondContact O-CE1 3.08Å
414I41.8Very low73.7Confident168 Ų16851.4 Ų51.486%0.86230%0.303SS*.THydrogen-bonded Turntrans-69.83.8-179.7-57.6165.4000112.2R385R385-I414 PolarHBondContact NH2-O 3.03Å; R385-I414 VanDerWaalsContact NH2-O 3.1Å
415T54.7Low73.4Confident44 Ų4451.6 Ų51.627%0.2730%0.303SS..THydrogen-bonded Turntrans-133.814.3-162.574.40000118.1R385 G413R385-T415 VanDerWaalsContact NH2-CB 3.28Å; G413-T415 PolarHBondContact O-N 3.33Å
416Y69.1Low73Confident79 Ų7951 Ų5131%0.3130%0.297SS..PPolyproline II helixtrans-86.4156.4174.362.5-90.4000112.5G411 G413 T418G411-Y416 WeakPolarHBondContact O-CB 3.46Å; G411-Y416 WeakPolarHBondContact O-CD1 3.23Å; G413-Y416 WeakPolarHBondContact O-CD1 3.45Å; G413-Y416 WeakPolarHBondContact O-CE1 3.08Å; Y416-T418 HydrophobicContact CD2-CG2 4.01Å; Y416-T418 HydrophobicContact CE2-CG2 3.67Å
417M72.3Confident72.6Confident22 Ų2256 Ų5611%0.10831%0.314CS..PPolyproline II helixtrans-99.5136.4161.4-68.3173.172.400109.4I406 L407 T408 A410 E421 Q422 T425I406-M417 HydrophobicContact CG2-SD 4.11Å; I406-M417 WeakPolarHBondContact O-CE 3.49Å; L407-M417 VanDerWaalsContact CA-SD 3.59Å; L407-M417 HydrophobicContact CD1-CE 4.38Å; T408-M417 PolarHBondContact N-SD 3.11Å; A410-M417 WeakPolarHBondContact CA-O 3.26Å; M417-E421 WeakPolarHBondContact CA-OE2 3.29Å; M417-E421 HydrophobicContact CB-CB 4.29Å; M417-E421 HydrophobicContact CE-CB 4.2Å; M417-Q422 HydrophobicContact CB-CG 3.86Å; M417-Q422 HydrophobicContact CE-CG 4.44Å; M417-Q422 PolarHBondContact O-NE2 3.33Å; M417-T425 HydrophobicContact CE-CG2 4.44Å; M417-T425 VanDerWaalsContact CE-OG1 3.28Å; M417-T425 WeakPolarHBondContact CE-OG1 3.25Å
418T73Confident72.7Confident12 Ų1258.1 Ų58.17%0.07433%0.326CS..PPolyproline II helixtrans-75.2168.4176.281.40000109.7Y416 N420 E421 Q422 E599Y416-T418 HydrophobicContact CD2-CG2 4.01Å; Y416-T418 HydrophobicContact CE2-CG2 3.67Å; T418-N420 VanDerWaalsContact C-N 3.29Å; T418-N420 PolarHBondContact O-N 3.36Å; T418-E421 PolarHBondContact N-OE2 2.89Å; T418-E421 PolarHBondContact O-N 2.83Å; T418-E421 WeakPolarHBondContact OG1-CG 3.48Å; T418-E421 PolarHBondContact OG1-N 2.87Å; T418-Q422 VanDerWaalsContact O-CG 3.23Å; T418-Q422 WeakPolarHBondContact O-CG 3.15Å; T418-Q422 PolarHBondContact O-N 2.79Å; T418-E599 WeakPolarHBondContact CB-OE2 3.33Å; T418-E599 HydrophobicContact CG2-CG 4.16Å; T418-E599 WeakPolarHBondContact CG2-OE1 3.41Å; T418-E599 WeakPolarHBondContact CG2-OE2 3.24Å; T418-E599 PolarHBondContact OG1-OE2 2.94Å
419Q71.4Confident72.9Confident53 Ų5358 Ų5825%0.24833%0.325CS..Hα-helixtrans-66.2-37.7-176.7-62.8-176.942.500111.3V60 D87 Q422 A423V60-Q419 VanDerWaalsContact CB-OE1 3.28Å; D87-Q419 PolarHBondContact OD1-NE2 2.84Å; D87-Q419 PolarHBondContact OD2-NE2 2.92Å; D87-Q419 PolarHBondContact OD2-OE1 3.26Å; D87-Q419 VanDerWaalsContact OD2-OE1 3.04Å; Q419-Q422 PolarHBondContact O-N 2.89Å; Q419-A423 WeakPolarHBondContact O-CB 3.3Å; Q419-A423 PolarHBondContact O-N 2.82Å
420N75.7Confident73.4Confident109 Ų10960.5 Ų60.558%0.58333%0.33SS*.Hα-helixtrans-63.9-45.5174.7-68.7-23.2000111.2T418 Q422 A423 D424T418-N420 VanDerWaalsContact C-N 3.29Å; T418-N420 PolarHBondContact O-N 3.36Å; N420-Q422 VanDerWaalsContact C-N 3.3Å; N420-Q422 PolarHBondContact O-N 3.37Å; N420-A423 PolarHBondContact O-N 2.99Å; N420-D424 WeakPolarHBondContact O-CB 3.46Å; N420-D424 PolarHBondContact O-N 3.23Å
421E82.6Confident74.4Confident84 Ų8462.8 Ų62.839%0.39333%0.334SS..Hα-helixtrans-61.9-37.8175.7-67.5177.3140.200112.3M417 T418 T425M417-E421 WeakPolarHBondContact CA-OE2 3.29Å; M417-E421 HydrophobicContact CB-CB 4.29Å; M417-E421 HydrophobicContact CE-CB 4.2Å; T418-E421 PolarHBondContact N-OE2 2.89Å; T418-E421 PolarHBondContact O-N 2.83Å; T418-E421 WeakPolarHBondContact OG1-CG 3.48Å; T418-E421 PolarHBondContact OG1-N 2.87Å; E421-T425 VanDerWaalsContact O-CB 3.27Å; E421-T425 WeakPolarHBondContact O-CB 3.23Å; E421-T425 PolarHBondContact O-N 3.11Å; E421-T425 PolarHBondContact O-OG1 3.43Å
422Q83Confident75.8Confident17 Ų1763.5 Ų63.58%0.07934%0.341CS..Hα-helixtrans-64.8-47.3174.3-71.2173.733.500110.8L407 T408 M417 T418 Q419 N420 T425 I426L407-Q422 HydrophobicContact CD1-CB 3.95Å; L407-Q422 HydrophobicContact CD1-CG 3.85Å; T408-Q422 VanDerWaalsContact O-CD 3.31Å; T408-Q422 PolarHBondContact O-NE2 2.84Å; M417-Q422 HydrophobicContact CB-CG 3.86Å; M417-Q422 HydrophobicContact CE-CG 4.44Å; M417-Q422 PolarHBondContact O-NE2 3.33Å; T418-Q422 VanDerWaalsContact O-CG 3.23Å; T418-Q422 WeakPolarHBondContact O-CG 3.15Å; T418-Q422 PolarHBondContact O-N 2.79Å; Q419-Q422 PolarHBondContact O-N 2.89Å; N420-Q422 VanDerWaalsContact C-N 3.3Å; N420-Q422 PolarHBondContact O-N 3.37Å; Q422-T425 PolarHBondContact O-N 2.98Å; Q422-I426 WeakPolarHBondContact O-CB 3.47Å; Q422-I426 WeakPolarHBondContact O-CD1 3.43Å; Q422-I426 WeakPolarHBondContact O-CG1 3.25Å; Q422-I426 PolarHBondContact O-N 3.1Å
423A80.6Confident78Confident48 Ų4860 Ų6040%0.39732%0.321SS..Hα-helixtrans-61.7-44.8179.300000111.8Q419 N420 I426 R427Q419-A423 WeakPolarHBondContact O-CB 3.3Å; Q419-A423 PolarHBondContact O-N 2.82Å; N420-A423 PolarHBondContact O-N 2.99Å; A423-I426 PolarHBondContact O-N 3.16Å; A423-R427 VanDerWaalsContact O-CB 3.31Å; A423-R427 WeakPolarHBondContact O-CB 3.41Å; A423-R427 PolarHBondContact O-N 2.65Å
424D86.4Confident80.1Confident67 Ų6759 Ų5936%0.35831%0.306SS..Hα-helixtrans-63.1-44.1176.5-76.8-24.5000111.5N420 R427 N428N420-D424 WeakPolarHBondContact O-CB 3.46Å; N420-D424 PolarHBondContact O-N 3.23Å; D424-R427 PolarHBondContact O-N 2.96Å; D424-R427 IonicContact OD1-CZ 3.11Å; D424-R427 VanDerWaalsContact OD1-CZ 3.23Å; D424-R427 IonicContact OD1-NH1 3.24Å; D424-R427 PolarHBondContact OD1-NH1 2.77Å; D424-R427 IonicContact OD1-NH2 2.72Å; D424-R427 PolarHBondContact OD1-NH2 3.25Å; D424-N428 WeakPolarHBondContact O-CB 3.47Å; D424-N428 PolarHBondContact O-N 3.39Å; D424-N428 PolarHBondContact O-ND2 3.15Å
425T89.8Confident82.6Confident19 Ų1952.3 Ų52.312%0.11727%0.271CS..Hα-helixtrans-60.4-47.2175.8-60.60000111.5A405 M417 E421 Q422 R427 N428 F429 L434 L437A405-T425 HydrophobicContact CB-CG2 4.03Å; M417-T425 HydrophobicContact CE-CG2 4.44Å; M417-T425 VanDerWaalsContact CE-OG1 3.28Å; M417-T425 WeakPolarHBondContact CE-OG1 3.25Å; E421-T425 VanDerWaalsContact O-CB 3.27Å; E421-T425 WeakPolarHBondContact O-CB 3.23Å; E421-T425 PolarHBondContact O-N 3.11Å; E421-T425 PolarHBondContact O-OG1 3.43Å; Q422-T425 PolarHBondContact O-N 2.98Å; T425-R427 VanDerWaalsContact C-N 3.34Å; T425-R427 PolarHBondContact O-N 3.43Å; T425-N428 PolarHBondContact O-N 3.06Å; T425-F429 WeakPolarHBondContact O-CB 3.43Å; T425-F429 PolarHBondContact O-N 3.14Å; T425-L434 HydrophobicContact CG2-CD1 4.12Å; T425-L437 HydrophobicContact CG2-CD2 3.72Å
426I87.1Confident84.6Confident8 Ų850.2 Ų50.24%0.04126%0.259CS..Hα-helixtrans-63-41.9178-70164.6000110.6L407 Q422 A423 F429 R430 L447L407-I426 HydrophobicContact CD1-CD1 4.36Å; L407-I426 HydrophobicContact CD1-CG1 4.25Å; L407-I426 HydrophobicContact CD2-CD1 4.25Å; L407-I426 HydrophobicContact CD2-CG1 3.9Å; Q422-I426 WeakPolarHBondContact O-CB 3.47Å; Q422-I426 WeakPolarHBondContact O-CD1 3.43Å; Q422-I426 WeakPolarHBondContact O-CG1 3.25Å; Q422-I426 PolarHBondContact O-N 3.1Å; A423-I426 PolarHBondContact O-N 3.16Å; I426-F429 PolarHBondContact O-N 3.36Å; I426-R430 HydrophobicContact CG2-CG 4.49Å; I426-R430 WeakPolarHBondContact O-CB 3.29Å; I426-R430 WeakPolarHBondContact O-CG 3.37Å; I426-R430 PolarHBondContact O-N 3.15Å; I426-L447 HydrophobicContact CB-CD1 4.35Å; I426-L447 HydrophobicContact CD1-CD1 3.75Å; I426-L447 HydrophobicContact CG1-CD1 3.76Å; I426-L447 HydrophobicContact CG2-CD1 3.64Å
427R86.5Confident85.8Confident130 Ų13046.5 Ų46.549%0.49124%0.244SC..Hα-helixtrans-62.6-47.7176.7-176.1-179.667.3-148.2-9.4111.2A423 D424 T425 F429 R430 N431A423-R427 VanDerWaalsContact O-CB 3.31Å; A423-R427 WeakPolarHBondContact O-CB 3.41Å; A423-R427 PolarHBondContact O-N 2.65Å; D424-R427 PolarHBondContact O-N 2.96Å; D424-R427 IonicContact OD1-CZ 3.11Å; D424-R427 VanDerWaalsContact OD1-CZ 3.23Å; D424-R427 IonicContact OD1-NH1 3.24Å; D424-R427 PolarHBondContact OD1-NH1 2.77Å; D424-R427 IonicContact OD1-NH2 2.72Å; D424-R427 PolarHBondContact OD1-NH2 3.25Å; T425-R427 VanDerWaalsContact C-N 3.34Å; T425-R427 PolarHBondContact O-N 3.43Å; R427-F429 VanDerWaalsContact C-N 3.27Å; R427-F429 PolarHBondContact O-N 3.26Å; R427-R430 PolarHBondContact O-N 3.25Å; R427-N431 WeakPolarHBondContact O-CB 3.24Å; R427-N431 PolarHBondContact O-N 3.34Å
428N91.4Very high86.9Confident49 Ų4945.4 Ų45.426%0.26224%0.239SC..Hα-helixtrans-62.8-35.7178.6-70.3-13.8000111.8D424 T425 G432 I433 L434D424-N428 WeakPolarHBondContact O-CB 3.47Å; D424-N428 PolarHBondContact O-N 3.39Å; D424-N428 PolarHBondContact O-ND2 3.15Å; T425-N428 PolarHBondContact O-N 3.06Å; N428-G432 PolarHBondContact O-N 3.37Å; N428-I433 HydrophobicContact CB-CB 4.16Å; N428-I433 HydrophobicContact CB-CG2 4.43Å; N428-I433 WeakPolarHBondContact O-CB 3.45Å; N428-I433 PolarHBondContact O-N 2.9Å; N428-L434 HydrophobicContact CB-CD1 3.74Å; N428-L434 HydrophobicContact CB-CG 3.96Å; N428-L434 PolarHBondContact O-N 3.46Å; N428-L434 VanDerWaalsContact O-N 3.1Å
429F90.8Very high87.9Confident0 Ų044.9 Ų44.90%024%0.235CC..Hα-helixtrans-69.3-41.9173.4-169.1-105.2000113.3R373 G374 I375 T425 I426 R427 N431 G432 L434 N435 L437 I449R373-F429 HydrophobicContact CB-CE1 4.3Å; R373-F429 HydrophobicContact CB-CZ 3.84Å; R373-F429 PolarHBondContact NH1-O 3.47Å; G374-F429 WeakPolarHBondContact O-CZ 3.42Å; I375-F429 HydrophobicContact CG1-CZ 4.45Å; T425-F429 WeakPolarHBondContact O-CB 3.43Å; T425-F429 PolarHBondContact O-N 3.14Å; I426-F429 PolarHBondContact O-N 3.36Å; R427-F429 VanDerWaalsContact C-N 3.27Å; R427-F429 PolarHBondContact O-N 3.26Å; F429-N431 VanDerWaalsContact C-N 3.29Å; F429-N431 PolarHBondContact O-N 3.39Å; F429-G432 PolarHBondContact O-N 3.17Å; F429-L434 HydrophobicContact CB-CB 4.27Å; F429-L434 HydrophobicContact CD2-CB 3.97Å; F429-L434 WeakPolarHBondContact CD2-O 3.11Å; F429-N435 WeakPolarHBondContact CE2-O 3.39Å; F429-L437 HydrophobicContact CB-CD1 4.14Å; F429-L437 HydrophobicContact CB-CD2 4.02Å; F429-L437 HydrophobicContact CB-CG 4.15Å; F429-L437 HydrophobicContact CD1-CD1 3.61Å; F429-L437 HydrophobicContact CD1-CG 3.96Å; F429-L437 HydrophobicContact CD2-CD1 4.09Å; F429-L437 HydrophobicContact CD2-CD2 3.87Å; F429-L437 HydrophobicContact CD2-CG 3.47Å; F429-L437 VanDerWaalsContact CD2-CG 3.47Å; F429-L437 HydrophobicContact CE1-CD1 3.95Å; F429-L437 HydrophobicContact CE1-CG 4.17Å; F429-L437 HydrophobicContact CE2-CB 4.35Å; F429-L437 HydrophobicContact CE2-CD1 4.34Å; F429-L437 HydrophobicContact CE2-CD2 4.47Å; F429-L437 HydrophobicContact CE2-CG 3.66Å; F429-L437 HydrophobicContact CG-CD1 3.67Å; F429-L437 HydrophobicContact CG-CD2 3.97Å; F429-L437 HydrophobicContact CG-CG 3.58Å; F429-L437 HydrophobicContact CZ-CD1 4.28Å; F429-L437 HydrophobicContact CZ-CG 4.01Å; F429-I449 HydrophobicContact CD1-CD1 3.5Å; F429-I449 VanDerWaalsContact CD1-CD1 3.5Å; F429-I449 HydrophobicContact CD1-CG1 4.11Å; F429-I449 HydrophobicContact CD1-CG2 4.25Å; F429-I449 HydrophobicContact CE1-CD1 3.54Å; F429-I449 HydrophobicContact CE1-CG1 4.27Å; F429-I449 HydrophobicContact CE1-CG2 3.93Å
430R85.8Confident88.7Confident66 Ų6642.9 Ų42.925%0.24923%0.227CC..Hα-helixtrans-63.7-33.6174.7-78177.3174158.94112.8R373 I426 R427 G432 D448 I449R373-R430 VanDerWaalsContact NH1-C 3.3Å; R373-R430 PolarHBondContact NH1-O 3.42Å; I426-R430 HydrophobicContact CG2-CG 4.49Å; I426-R430 WeakPolarHBondContact O-CB 3.29Å; I426-R430 WeakPolarHBondContact O-CG 3.37Å; I426-R430 PolarHBondContact O-N 3.15Å; R427-R430 PolarHBondContact O-N 3.25Å; R430-G432 VanDerWaalsContact C-N 3.28Å; R430-G432 PolarHBondContact O-N 3.24Å; R430-D448 PolarHBondContact NE-O 2.7Å; R430-D448 PolarHBondContact NH2-O 2.91Å; R430-I449 HydrophobicContact CG-CG1 4.3Å
431N87.8Confident89.2Confident111 Ų11141 Ų4159%0.59422%0.222SC*.THydrogen-bonded Turntrans-85.20.9178.8-65.6-8.6000113.3R427 F429 I433R427-N431 WeakPolarHBondContact O-CB 3.24Å; R427-N431 PolarHBondContact O-N 3.34Å; F429-N431 VanDerWaalsContact C-N 3.29Å; F429-N431 PolarHBondContact O-N 3.39Å; N431-I433 HydrophobicContact CB-CD1 4.4Å; N431-I433 HydrophobicContact CB-CG1 4.38Å; N431-I433 PolarHBondContact O-N 3.16Å
432G87.1Confident89.3Confident37 Ų3738.1 Ų38.138%0.38121%0.21SC..THydrogen-bonded Turntrans74.37.418000000114.7N428 F429 R430 L434N428-G432 PolarHBondContact O-N 3.37Å; F429-G432 PolarHBondContact O-N 3.17Å; R430-G432 VanDerWaalsContact C-N 3.28Å; R430-G432 PolarHBondContact O-N 3.24Å; G432-L434 VanDerWaalsContact C-N 3.28Å
433I92.3Very high89.4Confident93 Ų9337.4 Ų37.448%0.47721%0.207SC..SBendtrans-64.4-41.4171.2-61.6170.7000109.2K403 N428 N431K403-I433 WeakPolarHBondContact CD-O 3.38Å; N428-I433 HydrophobicContact CB-CB 4.16Å; N428-I433 HydrophobicContact CB-CG2 4.43Å; N428-I433 WeakPolarHBondContact O-CB 3.45Å; N428-I433 PolarHBondContact O-N 2.9Å; N431-I433 HydrophobicContact CB-CD1 4.4Å; N431-I433 HydrophobicContact CB-CG1 4.38Å; N431-I433 PolarHBondContact O-N 3.16Å
434L93.9Very high89.5Confident24 Ų2435.8 Ų35.813%0.12619%0.191CC..  trans-105.7144.4168.2-58.6168.9000108.9A405 T425 N428 F429 G432A405-L434 HydrophobicContact CB-CD1 3.52Å; A405-L434 HydrophobicContact CB-CD2 3.96Å; A405-L434 HydrophobicContact CB-CG 4.35Å; T425-L434 HydrophobicContact CG2-CD1 4.12Å; N428-L434 HydrophobicContact CB-CD1 3.74Å; N428-L434 HydrophobicContact CB-CG 3.96Å; N428-L434 PolarHBondContact O-N 3.46Å; N428-L434 VanDerWaalsContact O-N 3.1Å; F429-L434 HydrophobicContact CB-CB 4.27Å; F429-L434 HydrophobicContact CD2-CB 3.97Å; F429-L434 WeakPolarHBondContact CD2-O 3.11Å; G432-L434 VanDerWaalsContact C-N 3.28Å
435N93.7Very high89.3Confident26 Ų2633.5 Ų33.514%0.13918%0.178CC..  trans-128.4-3.6178.565.36.4000113.4F366 S372 R373 G374 G401 I402 K403 F429F366-N435 HydrophobicContact CE1-CB 4.06Å; F366-N435 VanDerWaalsContact CE1-O 3.29Å; F366-N435 WeakPolarHBondContact CE1-O 3.44Å; F366-N435 VanDerWaalsContact CZ-O 3.25Å; F366-N435 WeakPolarHBondContact CZ-O 3.3Å; S372-N435 WeakPolarHBondContact O-CB 3.21Å; R373-N435 WeakPolarHBondContact CA-O 3.41Å; G374-N435 PolarHBondContact N-O 3.38Å; G401-N435 PolarHBondContact O-ND2 2.88Å; I402-N435 WeakPolarHBondContact CA-OD1 3.4Å; K403-N435 PolarHBondContact N-OD1 3.17Å; K403-N435 PolarHBondContact O-N 2.91Å; K403-N435 PolarHBondContact O-OD1 3.4Å; F429-N435 WeakPolarHBondContact CE2-O 3.39Å
436L95.9Very high88.4Confident1 Ų132.9 Ų32.91%0.00518%0.176CC..EExtended strand (participates in β ladder)trans-130.3124167-177.863.7000111.7L362 F366 G374 L376 V391 I402 K403 A404 A405 I438L362-L436 HydrophobicContact CD1-CD2 4.3Å; L362-L436 HydrophobicContact CD2-CD1 4.07Å; L362-L436 HydrophobicContact CD2-CD2 4.22Å; F366-L436 HydrophobicContact CE2-CD1 4.4Å; F366-L436 HydrophobicContact CZ-CB 4.3Å; F366-L436 HydrophobicContact CZ-CD1 4.29Å; G374-L436 WeakPolarHBondContact O-CA 3.26Å; L376-L436 HydrophobicContact CB-CD1 4.21Å; V391-L436 HydrophobicContact CG1-CD2 4.44Å; V391-L436 HydrophobicContact CG2-CD2 4.22Å; I402-L436 HydrophobicContact CG2-CB 3.83Å; I402-L436 HydrophobicContact CG2-CD2 3.7Å; I402-L436 HydrophobicContact CG2-CG 4.43Å; K403-L436 PolarHBondContact O-N 3.28Å; A404-L436 VanDerWaalsContact CA-O 3.23Å; A404-L436 WeakPolarHBondContact CA-O 3.38Å; A404-L436 HydrophobicContact CB-CB 4.04Å; A404-L436 HydrophobicContact CB-CD2 4.1Å; A404-L436 HydrophobicContact CB-CG 4.26Å; A405-L436 PolarHBondContact N-O 2.88Å; A405-L436 VanDerWaalsContact N-O 3.12Å; L436-I438 HydrophobicContact CD2-CG1 4.49Å; L436-I438 HydrophobicContact CG-CG1 4.39Å
437L95.6Very high87.9Confident0 Ų032.6 Ų32.60%018%0.175CC..EExtended strand (participates in β ladder)trans-98.9128.3167.3-70179.4000110.5G374 I375 L376 L407 T425 F429 L447 I449G374-L437 PolarHBondContact O-N 3.42Å; I375-L437 CarbonylContact C-O 3.57Å; I375-L437 WeakPolarHBondContact CA-O 3.22Å; I375-L437 HydrophobicContact CG1-CB 4.39Å; I375-L437 HydrophobicContact CG2-CB 4.43Å; L376-L437 PolarHBondContact N-O 2.92Å; L407-L437 HydrophobicContact CD2-CD1 4.14Å; T425-L437 HydrophobicContact CG2-CD2 3.72Å; F429-L437 HydrophobicContact CB-CD1 4.14Å; F429-L437 HydrophobicContact CB-CD2 4.02Å; F429-L437 HydrophobicContact CB-CG 4.15Å; F429-L437 HydrophobicContact CD1-CD1 3.61Å; F429-L437 HydrophobicContact CD1-CG 3.96Å; F429-L437 HydrophobicContact CD2-CD1 4.09Å; F429-L437 HydrophobicContact CD2-CD2 3.87Å; F429-L437 HydrophobicContact CD2-CG 3.47Å; F429-L437 VanDerWaalsContact CD2-CG 3.47Å; F429-L437 HydrophobicContact CE1-CD1 3.95Å; F429-L437 HydrophobicContact CE1-CG 4.17Å; F429-L437 HydrophobicContact CE2-CB 4.35Å; F429-L437 HydrophobicContact CE2-CD1 4.34Å; F429-L437 HydrophobicContact CE2-CD2 4.47Å; F429-L437 HydrophobicContact CE2-CG 3.66Å; F429-L437 HydrophobicContact CG-CD1 3.67Å; F429-L437 HydrophobicContact CG-CD2 3.97Å; F429-L437 HydrophobicContact CG-CG 3.58Å; F429-L437 HydrophobicContact CZ-CD1 4.28Å; F429-L437 HydrophobicContact CZ-CG 4.01Å; L437-L447 HydrophobicContact CD1-CD2 4.06Å; L437-I449 HydrophobicContact CD1-CD1 4.46Å
438I95.4Very high87.3Confident0 Ų028 Ų280%016%0.16CC..EExtended strand (participates in β ladder)trans-103.8102.2172.1-52.7177.2000107.5L376 T384 L387 L388 V391 A404 A405 I406 L407 L436L376-I438 HydrophobicContact CB-CG1 4.48Å; L376-I438 HydrophobicContact CD2-CG1 4.33Å; L376-I438 HydrophobicContact CD2-CG2 4.4Å; L376-I438 CarbonylContact O-C 3.49Å; L376-I438 WeakPolarHBondContact O-CA 3.37Å; T384-I438 HydrophobicContact CG2-CG2 4.07Å; L387-I438 HydrophobicContact CB-CD1 4.15Å; L387-I438 HydrophobicContact CB-CG2 3.86Å; L387-I438 HydrophobicContact CD1-CG2 4.08Å; L388-I438 HydrophobicContact CB-CD1 4.03Å; L388-I438 HydrophobicContact CD1-CD1 4.2Å; V391-I438 HydrophobicContact CG2-CD1 4.11Å; A404-I438 HydrophobicContact CB-CD1 4.16Å; A405-I438 PolarHBondContact O-N 2.83Å; I406-I438 CarbonylContact C-O 3.57Å; I406-I438 VanDerWaalsContact CA-O 3.25Å; I406-I438 WeakPolarHBondContact CA-O 3.21Å; L407-I438 PolarHBondContact N-O 3.49Å; L436-I438 HydrophobicContact CD2-CG1 4.49Å; L436-I438 HydrophobicContact CG-CG1 4.39Å
439S92.3Very high86.5Confident0 Ų025.9 Ų25.90%015%0.149CC..EExtended strand (participates in β ladder)trans-121.2150.3-165.4-1760000113.4L376 F377 S378 L407 A443L376-S439 PolarHBondContact O-N 3.15Å; F377-S439 CarbonylContact C-O 3.6Å; F377-S439 VanDerWaalsContact CA-O 3.3Å; F377-S439 WeakPolarHBondContact CA-O 3.44Å; S378-S439 PolarHBondContact N-O 2.82Å; L407-S439 VanDerWaalsContact O-CA 3.24Å; L407-S439 WeakPolarHBondContact O-CA 3.41Å; L407-S439 PolarHBondContact O-OG 3.23Å; L407-S439 VanDerWaalsContact O-OG 3.07Å; S439-A443 WeakPolarHBondContact OG-CB 2.86Å; S439-A443 PolarHBondContact OG-N 2.73Å
440T89.9Confident85.8Confident11 Ų1129.1 Ų29.17%0.06717%0.17CC..  trans-80.1-166.4157.560.40000110.2F377 S378 R381 T384 L407 T408 V442 A443F377-T440 WeakPolarHBondContact CD1-O 3.36Å; S378-T440 WeakPolarHBondContact O-CA 3.19Å; R381-T440 HydrophobicContact CG-CG2 4.33Å; T384-T440 HydrophobicContact CG2-CG2 3.9Å; L407-T440 PolarHBondContact O-N 3.36Å; T408-T440 HydrophobicContact CG2-CG2 4.03Å; T440-V442 PolarHBondContact O-N 3.44Å; T440-A443 PolarHBondContact O-N 3.34Å
441S85.6Confident85.6Confident70 Ų7030.1 Ų30.149%0.4918%0.177SC..G310 helixtrans-59.5-4.2176.458.40000115.6A443 E444S441-A443 VanDerWaalsContact C-N 3.27Å; S441-A443 PolarHBondContact O-N 3.11Å; S441-E444 VanDerWaalsContact CA-CD 3.46Å; S441-E444 VanDerWaalsContact CB-CD 3.49Å; S441-E444 WeakPolarHBondContact CB-OE2 3.32Å; S441-E444 WeakPolarHBondContact O-CB 3.36Å; S441-E444 PolarHBondContact O-N 3.27Å; S441-E444 VanDerWaalsContact O-N 3.17Å
442V84.5Confident85.6Confident24 Ų2424.8 Ų24.815%0.14515%0.149CC..G310 helixtrans-64.6-31.1-179171.70000112.3K59 T440K59-V442 PolarHBondContact NZ-O 2.94Å; T440-V442 PolarHBondContact O-N 3.44Å
443A84.1Confident85.8Confident1 Ų124.1 Ų24.11%0.00814%0.136CC..G310 helixtrans-94.6-1.8175.400000114.6F377 L407 S439 T440 S441 E445 L447F377-A443 HydrophobicContact CE1-CB 3.78Å; F377-A443 HydrophobicContact CZ-CB 4.11Å; L407-A443 HydrophobicContact CD2-CB 3.91Å; S439-A443 WeakPolarHBondContact OG-CB 2.86Å; S439-A443 PolarHBondContact OG-N 2.73Å; T440-A443 PolarHBondContact O-N 3.34Å; S441-A443 VanDerWaalsContact C-N 3.27Å; S441-A443 PolarHBondContact O-N 3.11Å; A443-E445 VanDerWaalsContact C-N 3.32Å; A443-E445 PolarHBondContact O-N 2.91Å; A443-L447 HydrophobicContact CB-CD2 3.81Å
444E83.9Confident85.8Confident15 Ų1519.7 Ų19.77%0.0711%0.114CC..THydrogen-bonded Turntrans-65.2-39-178.2-73.2173.7176.600111.2F377 S441 Q469 A470 R473F377-E444 HydrophobicContact CD1-CG 3.87Å; F377-E444 HydrophobicContact CE1-CB 4.3Å; F377-E444 HydrophobicContact CE1-CG 3.51Å; F377-E444 HydrophobicContact CZ-CB 4.44Å; F377-E444 HydrophobicContact CZ-CG 3.89Å; S441-E444 VanDerWaalsContact CA-CD 3.46Å; S441-E444 VanDerWaalsContact CB-CD 3.49Å; S441-E444 WeakPolarHBondContact CB-OE2 3.32Å; S441-E444 WeakPolarHBondContact O-CB 3.36Å; S441-E444 PolarHBondContact O-N 3.27Å; S441-E444 VanDerWaalsContact O-N 3.17Å; E444-Q469 CarbonylContact O-C 3.51Å; E444-Q469 VanDerWaalsContact O-C 3.27Å; E444-Q469 WeakPolarHBondContact O-CB 3.48Å; E444-Q469 VanDerWaalsContact O-O 3.09Å; E444-A470 HydrophobicContact CG-CB 4.28Å; E444-R473 PolarHBondContact O-NE 2.9Å; E444-R473 PolarHBondContact O-NH2 2.89Å
445E82.1Confident85.8Confident18 Ų1818.6 Ų18.68%0.08411%0.108CC..SBendtrans-116.3147.4179.9-69.2173-157.500111.3N58 K59 H138 H139 A443 L447 Q469N58-E445 PolarHBondContact ND2-OE2 2.97Å; K59-E445 PolarHBondContact NZ-O 3.44Å; H138-E445 IonicContact NE2-OE1 3Å; H138-E445 PolarHBondContact NE2-OE1 3.39Å; H139-E445 IonicContact CD2-OE2 2.65Å; H139-E445 IonicContact CE1-OE1 3.47Å; H139-E445 IonicContact CE1-OE2 3.45Å; H139-E445 IonicContact NE2-OE1 2.98Å; H139-E445 PolarHBondContact NE2-OE1 3.38Å; H139-E445 IonicContact NE2-OE2 3.52Å; H139-E445 PolarHBondContact NE2-OE2 2.96Å; A443-E445 VanDerWaalsContact C-N 3.32Å; A443-E445 PolarHBondContact O-N 2.91Å; E445-L447 PolarHBondContact O-N 3.16Å; E445-L447 VanDerWaalsContact O-N 3.15Å; E445-Q469 HydrophobicContact CG-CB 3.98Å; E445-Q469 HydrophobicContact CG-CG 3.81Å
446G70.3Confident85.9Confident7 Ų717.4 Ų17.47%0.07210%0.101CC..SBendtrans81.5-2416800000116.3L62 Q65 D448L62-G446 VanDerWaalsContact CD2-O 3.22Å; L62-G446 WeakPolarHBondContact CD2-O 3.48Å; Q65-G446 PolarHBondContact NE2-O 3.11Å; Q65-G446 PolarHBondContact OE1-O 2.67Å; G446-D448 PolarHBondContact O-N 3.33Å
447L76.4Confident85.6Confident2 Ų217.5 Ų17.51%0.0110%0.102CC..  trans-74114.7-178.1-167.164.3000111.8I375 L407 I426 L437 A443 E445 I449 R473I375-L447 HydrophobicContact CD1-CD2 4.43Å; L407-L447 HydrophobicContact CD2-CD2 4.17Å; I426-L447 HydrophobicContact CB-CD1 4.35Å; I426-L447 HydrophobicContact CD1-CD1 3.75Å; I426-L447 HydrophobicContact CG1-CD1 3.76Å; I426-L447 HydrophobicContact CG2-CD1 3.64Å; L437-L447 HydrophobicContact CD1-CD2 4.06Å; A443-L447 HydrophobicContact CB-CD2 3.81Å; E445-L447 PolarHBondContact O-N 3.16Å; E445-L447 VanDerWaalsContact O-N 3.15Å; L447-I449 HydrophobicContact CD1-CD1 4.2Å; L447-I449 HydrophobicContact CD2-CD1 3.34Å; L447-I449 HydrophobicContact CD2-CG1 4.49Å; L447-I449 HydrophobicContact CG-CD1 3.46Å; L447-I449 VanDerWaalsContact CG-CD1 3.46Å; L447-I449 HydrophobicContact CG-CG1 4.13Å; L447-R473 WeakPolarHBondContact O-CD 3.46Å; L447-R473 PolarHBondContact O-NH1 2.88Å
448D73.6Confident85.2Confident34 Ų3417.5 Ų17.518%0.18210%0.102CC..  trans-98.4107178.3-179.648.5000112.2K69 R430 G446 R475K69-D448 IonicContact NZ-OD2 3.02Å; K69-D448 PolarHBondContact NZ-OD2 3Å; R430-D448 PolarHBondContact NE-O 2.7Å; R430-D448 PolarHBondContact NH2-O 2.91Å; G446-D448 PolarHBondContact O-N 3.33Å; D448-R475 IonicContact OD1-CZ 2.61Å; D448-R475 IonicContact OD1-NH1 3.34Å; D448-R475 PolarHBondContact OD1-NH1 3.38Å; D448-R475 IonicContact OD1-NH2 3.23Å
449I76.1Confident84.1Confident4 Ų418.2 Ų18.22%0.02111%0.109CC..  trans-138.494177.2-58147.5000108.7I375 F429 R430 L437 L447 E451 C452I375-I449 HydrophobicContact CD1-CD1 4.37Å; F429-I449 HydrophobicContact CD1-CD1 3.5Å; F429-I449 VanDerWaalsContact CD1-CD1 3.5Å; F429-I449 HydrophobicContact CD1-CG1 4.11Å; F429-I449 HydrophobicContact CD1-CG2 4.25Å; F429-I449 HydrophobicContact CE1-CD1 3.54Å; F429-I449 HydrophobicContact CE1-CG1 4.27Å; F429-I449 HydrophobicContact CE1-CG2 3.93Å; R430-I449 HydrophobicContact CG-CG1 4.3Å; L437-I449 HydrophobicContact CD1-CD1 4.46Å; L447-I449 HydrophobicContact CD1-CD1 4.2Å; L447-I449 HydrophobicContact CD2-CD1 3.34Å; L447-I449 HydrophobicContact CD2-CG1 4.49Å; L447-I449 HydrophobicContact CG-CD1 3.46Å; L447-I449 VanDerWaalsContact CG-CD1 3.46Å; L447-I449 HydrophobicContact CG-CG1 4.13Å; I449-E451 VanDerWaalsContact C-N 3.27Å; I449-E451 PolarHBondContact O-N 3.08Å; I449-C452 HydrophobicContact CB-CB 4.26Å; I449-C452 HydrophobicContact CG2-CB 3.99Å; I449-C452 WeakPolarHBondContact O-CB 3.42Å; I449-C452 PolarHBondContact O-N 3.2Å
450P74.9Confident83.6Confident68 Ų6818.8 Ų18.844%0.44211%0.112SC..THydrogen-bonded Turntrans-59.4-33.1-178.8-26.736.1000114.5C452 A476P450-C452 VanDerWaalsContact C-N 3.26Å; P450-C452 PolarHBondContact O-N 3.49Å; P450-A476 PolarHBondContact O-N 3.33Å
451E82.4Confident83.2Confident86 Ų8621.4 Ų21.440%0.40213%0.125SC..THydrogen-bonded Turntrans-82.4-0.3-174.8-52.887167.400113.6R373 I449 N453R373-E451 IonicContact NH2-OE1 3.4Å; I449-E451 VanDerWaalsContact C-N 3.27Å; I449-E451 PolarHBondContact O-N 3.08Å; E451-N453 PolarHBondContact O-N 3.38Å
452C88.2Confident83.2Confident0 Ų019.3 Ų19.30%011%0.109CC..  trans-69.2117.8178.1-176.50000110.1R373 I449 P450 R473 A474 R475 A476R373-C452 WeakPolarHBondContact O-CA 3.24Å; R373-C452 PolarHBondContact O-SG 3.05Å; I449-C452 HydrophobicContact CB-CB 4.26Å; I449-C452 HydrophobicContact CG2-CB 3.99Å; I449-C452 WeakPolarHBondContact O-CB 3.42Å; I449-C452 PolarHBondContact O-N 3.2Å; P450-C452 VanDerWaalsContact C-N 3.26Å; P450-C452 PolarHBondContact O-N 3.49Å; C452-R473 WeakPolarHBondContact CB-O 3.24Å; C452-R473 PolarHBondContact SG-O 3.28Å; C452-A474 WeakPolarHBondContact O-CA 3.39Å; C452-R475 PolarHBondContact O-N 3.28Å; C452-A476 PolarHBondContact O-N 2.71Å
453N90.4Very high83.3Confident23 Ų2321.5 Ų21.512%0.12312%0.12CC..  trans-115.2-8.5-176.169.1-21.6000113.6S372 R373 E451 A476 S479 Q480S372-N453 PolarHBondContact OG-ND2 3.48Å; R373-N453 PolarHBondContact N-OD1 2.8Å; R373-N453 PolarHBondContact O-N 3.11Å; R373-N453 PolarHBondContact O-OD1 3.42Å; E451-N453 PolarHBondContact O-N 3.38Å; N453-A476 HydrophobicContact CB-CB 3.79Å; N453-S479 CarbonylContact O-C 3.58Å; N453-S479 WeakPolarHBondContact O-CA 3.28Å; N453-S479 WeakPolarHBondContact O-CB 3.45Å; N453-Q480 PolarHBondContact O-N 2.65Å
454L93.3Very high83.6Confident0 Ų021.7 Ų21.70%012%0.121CC..EExtended strand (participates in β ladder)trans-132.5130.5174.117763.5000111.5T361 L362 Q365 F366 R373 G374 I375 V456 Q480T361-L454 HydrophobicContact CG2-CD1 4.42Å; L362-L454 HydrophobicContact CD2-CD2 4.04Å; Q365-L454 HydrophobicContact CB-CB 4.43Å; Q365-L454 HydrophobicContact CB-CD2 3.98Å; Q365-L454 HydrophobicContact CG-CB 4.27Å; Q365-L454 HydrophobicContact CG-CD1 4.11Å; Q365-L454 HydrophobicContact CG-CD2 4.04Å; Q365-L454 HydrophobicContact CG-CG 4.34Å; F366-L454 HydrophobicContact CE2-CD2 4.02Å; R373-L454 PolarHBondContact O-N 2.86Å; G374-L454 CarbonylContact C-O 3.57Å; G374-L454 VanDerWaalsContact CA-O 3.24Å; G374-L454 WeakPolarHBondContact CA-O 3Å; I375-L454 PolarHBondContact N-O 3.36Å; L454-V456 HydrophobicContact CD1-CG2 3.79Å; L454-V456 HydrophobicContact CD2-CG2 3.8Å; L454-V456 HydrophobicContact CG-CG2 3.77Å; L454-Q480 WeakPolarHBondContact CA-O 3.47Å; L454-Q480 HydrophobicContact CD1-CB 4.05Å; L454-Q480 HydrophobicContact CD1-CG 4.32Å
455V94.1Very high83.9Confident0 Ų021.8 Ų21.80%012%0.122CC..EExtended strand (participates in β ladder)trans-122.7123.5164.2171.80000108.5I375 F377 R457 R473 A474 Q480 Y481 S482I375-V455 CarbonylContact O-C 3.52Å; I375-V455 WeakPolarHBondContact O-CA 3.25Å; F377-V455 HydrophobicContact CD2-CG1 3.87Å; F377-V455 HydrophobicContact CE2-CG1 3.86Å; V455-R457 HydrophobicContact CG1-CG 4.49Å; V455-R473 HydrophobicContact CG2-CB 3.92Å; V455-A474 HydrophobicContact CB-CB 4.32Å; V455-A474 HydrophobicContact CG2-CB 3.75Å; V455-Q480 PolarHBondContact N-O 3.39Å; V455-Y481 HydrophobicContact CB-CD2 3.99Å; V455-Y481 HydrophobicContact CG1-CD2 3.72Å; V455-Y481 HydrophobicContact CG1-CE2 3.99Å; V455-Y481 CarbonylContact O-C 3.55Å; V455-Y481 WeakPolarHBondContact O-CA 3.4Å; V455-S482 PolarHBondContact O-N 2.96Å
456V94.4Very high84.1Confident1 Ų121.2 Ų21.21%0.00612%0.12CC..EExtended strand (participates in β ladder)trans-113.5125.2175.3-173.60000109.2L358 T361 I375 L376 F377 L454 S482 V484L358-V456 HydrophobicContact CD1-CG1 3.77Å; T361-V456 HydrophobicContact CG2-CG2 3.97Å; I375-V456 PolarHBondContact O-N 2.84Å; L376-V456 HydrophobicContact CD1-CB 3.79Å; L376-V456 HydrophobicContact CD1-CG1 3.79Å; F377-V456 PolarHBondContact N-O 3.38Å; L454-V456 HydrophobicContact CD1-CG2 3.79Å; L454-V456 HydrophobicContact CD2-CG2 3.8Å; L454-V456 HydrophobicContact CG-CG2 3.77Å; V456-S482 WeakPolarHBondContact CA-O 3.39Å; V456-V484 HydrophobicContact CG1-CG2 3.9Å
457R90.9Very high85Confident3 Ų321.2 Ų21.21%0.01112%0.118CC..EExtended strand (participates in β ladder)trans-103.8110.8172.1-68.2-171.974.9-145.7-11.2109.8V455 L460 T462 Y481 S482 V484 E495V455-R457 HydrophobicContact CG1-CG 4.49Å; R457-L460 HydrophobicContact CB-CD1 4.06Å; R457-L460 HydrophobicContact CG-CD1 4.18Å; R457-T462 VanDerWaalsContact NH2-CG2 3.26Å; R457-T462 PolarHBondContact NH2-OG1 3.04Å; R457-Y481 VanDerWaalsContact CD-CZ 3.45Å; R457-Y481 WeakPolarHBondContact CD-OH 3.31Å; R457-Y481 HydrophobicContact CG-CE2 3.95Å; R457-Y481 PolarHBondContact NH1-OH 3.16Å; R457-Y481 VanDerWaalsContact NH1-OH 3.09Å; R457-S482 PolarHBondContact N-O 3.26Å; R457-V484 PolarHBondContact O-N 2.87Å; R457-E495 IonicContact CZ-OE2 3.77Å; R457-E495 IonicContact NH1-OE1 3.69Å; R457-E495 IonicContact NH1-OE2 3.42Å; R457-E495 PolarHBondContact NH1-OE2 3.37Å
458Y86Confident85.5Confident1 Ų122.4 Ų22.40%0.00412%0.124CC..EExtended strand (participates in β ladder)trans-110.2105.7-168.6-167.8-100.6000111.5T301 L302 K354 M355 L358 L376 F377 L387 L460 V484T301-Y458 HydrophobicContact CG2-CD1 3.97Å; T301-Y458 HydrophobicContact CG2-CE1 3.79Å; T301-Y458 WeakPolarHBondContact O-CE1 3.03Å; T301-Y458 VanDerWaalsContact O-CZ 3.27Å; T301-Y458 PolarHBondContact O-OH 2.9Å; L302-Y458 HydrophobicContact CD2-CE1 3.87Å; K354-Y458 VanDerWaalsContact C-OH 3.28Å; K354-Y458 HydrophobicContact CB-CE2 4.02Å; K354-Y458 VanDerWaalsContact CB-OH 3.28Å; K354-Y458 WeakPolarHBondContact CB-OH 3.27Å; K354-Y458 WeakPolarHBondContact O-CE2 3.06Å; K354-Y458 PolarHBondContact O-OH 3.32Å; M355-Y458 PolarHBondContact N-OH 2.92Å; M355-Y458 HydrophobicContact SD-CE1 4.46Å; M355-Y458 PolarHBondContact SD-OH 3.33Å; L358-Y458 HydrophobicContact CB-CD2 4.2Å; L358-Y458 HydrophobicContact CB-CE2 3.76Å; L358-Y458 HydrophobicContact CD1-CD2 4.2Å; L358-Y458 HydrophobicContact CD2-CD2 3.91Å; L358-Y458 HydrophobicContact CD2-CE2 3.8Å; L358-Y458 HydrophobicContact CD2-CG 4.36Å; L358-Y458 HydrophobicContact CG-CD2 4.33Å; L358-Y458 HydrophobicContact CG-CE2 4.25Å; L376-Y458 HydrophobicContact CD1-CG 4.35Å; F377-Y458 PolarHBondContact O-N 2.94Å; L387-Y458 HydrophobicContact CD1-CD1 4.47Å; L387-Y458 HydrophobicContact CD2-CE1 4.36Å; Y458-L460 VanDerWaalsContact C-N 3.3Å; Y458-L460 PolarHBondContact O-N 3.44Å; Y458-V484 HydrophobicContact CD2-CB 3.82Å; Y458-V484 HydrophobicContact CD2-CG1 4.02Å; Y458-V484 HydrophobicContact CD2-CG2 4.25Å; Y458-V484 HydrophobicContact CE2-CB 4.16Å; Y458-V484 HydrophobicContact CE2-CG1 3.81Å
459G73.9Confident86.2Confident14 Ų1420.8 Ų20.814%0.14412%0.115CC..SBendtrans65.230.4178.700000113.9
460L80.6Confident86.7Confident13 Ų1320.6 Ų20.67%0.06811%0.114CC..  trans-98.1134.1-174.4-66.8-179.9000112.8F377 R379 R457 Y458 T462F377-L460 HydrophobicContact CB-CD1 3.44Å; F377-L460 VanDerWaalsContact CB-CD1 3.44Å; R379-L460 HydrophobicContact CB-CD2 3.81Å; R379-L460 VanDerWaalsContact N-CD2 3.34Å; R457-L460 HydrophobicContact CB-CD1 4.06Å; R457-L460 HydrophobicContact CG-CD1 4.18Å; Y458-L460 VanDerWaalsContact C-N 3.3Å; Y458-L460 PolarHBondContact O-N 3.44Å; L460-T462 HydrophobicContact CB-CG2 4.43Å
461L80.9Confident87.3Confident65 Ų6518.7 Ų18.734%0.3410%0.103SC..  trans-120.387.4171.5-61.8173.6000108.3R490 E491 R494L461-R490 HydrophobicContact CD1-CB 4.31Å; L461-R490 HydrophobicContact CD2-CB 4.15Å; L461-R490 WeakPolarHBondContact CD2-O 3.43Å; L461-E491 HydrophobicContact CD2-CB 4.36Å; L461-E491 HydrophobicContact CD2-CG 4.17Å; L461-R494 HydrophobicContact CD2-CB 3.64Å; L461-R494 HydrophobicContact CD2-CG 4.05Å
462T85.4Confident87.4Confident27 Ų2715.2 Ų15.217%0.1669%0.09CC..  trans-114.5178.7179.772.20000111.4R457 L460 A466 R494 N498R457-T462 VanDerWaalsContact NH2-CG2 3.26Å; R457-T462 PolarHBondContact NH2-OG1 3.04Å; L460-T462 HydrophobicContact CB-CG2 4.43Å; T462-A466 HydrophobicContact CG2-CB 4.24Å; T462-R494 PolarHBondContact O-NE 2.87Å; T462-R494 PolarHBondContact O-NH2 2.83Å; T462-R494 VanDerWaalsContact O-NH2 3.14Å; T462-N498 PolarHBondContact O-ND2 2.55Å; T462-N498 VanDerWaalsContact O-ND2 3.1Å; T462-N498 PolarHBondContact O-OD1 2.83Å
463N87.9Confident87.3Confident69 Ų6915.7 Ų15.737%0.3699%0.092SC..  trans-78.7172.1168.367.33.2000112.6I465 A466 Q467N463-I465 VanDerWaalsContact C-N 3.3Å; N463-I465 PolarHBondContact O-N 3.45Å; N463-A466 PolarHBondContact O-N 3.11Å; N463-A466 WeakPolarHBondContact OD1-CB 3.38Å; N463-A466 PolarHBondContact OD1-N 3.13Å; N463-Q467 PolarHBondContact O-N 3.4Å; N463-Q467 VanDerWaalsContact O-N 3.11Å
464E90.6Very high87Confident6 Ų614.7 Ų14.73%0.0289%0.086CC..Hα-helixtrans-61.4-35.9179.673.2-70.417400112.3G175 T176 Q467 Q468 N498 L501G175-E464 WeakPolarHBondContact CA-OE1 3.39Å; T176-E464 PolarHBondContact N-OE1 3.21Å; E464-Q467 WeakPolarHBondContact O-CB 3.23Å; E464-Q467 PolarHBondContact O-N 2.84Å; E464-Q468 WeakPolarHBondContact O-CB 3.45Å; E464-Q468 PolarHBondContact O-N 2.88Å; E464-N498 HydrophobicContact CB-CB 4.16Å; E464-N498 PolarHBondContact N-OD1 3.34Å; E464-L501 HydrophobicContact CB-CB 3.9Å; E464-L501 HydrophobicContact CG-CB 3.97Å
465I89.1Confident86.2Confident16 Ų1617.5 Ų17.58%0.08210%0.097CC..Hα-helixtrans-62.8-52.1176.9-58178.3000110N463 Q467 Q468 Q469N463-I465 VanDerWaalsContact C-N 3.3Å; N463-I465 PolarHBondContact O-N 3.45Å; I465-Q467 VanDerWaalsContact C-N 3.29Å; I465-Q467 PolarHBondContact O-N 2.92Å; I465-Q468 PolarHBondContact O-N 3.45Å; I465-Q469 HydrophobicContact CG2-CG 4.13Å; I465-Q469 WeakPolarHBondContact O-CB 3.41Å; I465-Q469 WeakPolarHBondContact O-CG 3.33Å; I465-Q469 PolarHBondContact O-N 3.17Å
466A87.8Confident85.6Confident7 Ų718.5 Ų18.56%0.05811%0.106CC..Hα-helixtrans-63.1-36.2179.800000112.1T462 N463 A470T462-A466 HydrophobicContact CG2-CB 4.24Å; N463-A466 PolarHBondContact O-N 3.11Å; N463-A466 WeakPolarHBondContact OD1-CB 3.38Å; N463-A466 PolarHBondContact OD1-N 3.13Å; A466-A470 WeakPolarHBondContact O-CB 3.36Å; A466-A470 PolarHBondContact O-N 3.49Å
467Q88.7Confident84.7Confident6 Ų628.7 Ų28.73%0.02814%0.144CC..Hα-helixtrans-58.7-53.2172.1169.8177.7-48.200111.3N463 E464 I465 Q469 A470 S471 Y481 E495 N498N463-Q467 PolarHBondContact O-N 3.4Å; N463-Q467 VanDerWaalsContact O-N 3.11Å; E464-Q467 WeakPolarHBondContact O-CB 3.23Å; E464-Q467 PolarHBondContact O-N 2.84Å; I465-Q467 VanDerWaalsContact C-N 3.29Å; I465-Q467 PolarHBondContact O-N 2.92Å; Q467-Q469 VanDerWaalsContact C-N 3.32Å; Q467-Q469 PolarHBondContact O-N 3.1Å; Q467-A470 PolarHBondContact O-N 2.79Å; Q467-S471 VanDerWaalsContact O-CB 3.32Å; Q467-S471 WeakPolarHBondContact O-CB 3.42Å; Q467-S471 PolarHBondContact O-N 3.39Å; Q467-Y481 WeakPolarHBondContact CG-OH 3.46Å; Q467-E495 WeakPolarHBondContact CG-OE1 3.35Å; Q467-E495 PolarHBondContact OE1-OE1 2.87Å; Q467-E495 PolarHBondContact OE1-OE2 3.16Å; Q467-E495 VanDerWaalsContact OE1-OE2 3.13Å; Q467-N498 PolarHBondContact OE1-ND2 3.21Å
468Q86.9Confident84.3Confident27 Ų2736 Ų3613%0.12618%0.183CC..Hα-helixtrans-65.1-38.4-176.8-166.6-174.7-19.300111.5A172 S173 E464 I465 G472A172-Q468 PolarHBondContact O-NE2 2.83Å; S173-Q468 PolarHBondContact OG-OE1 2.94Å; E464-Q468 WeakPolarHBondContact O-CB 3.45Å; E464-Q468 PolarHBondContact O-N 2.88Å; I465-Q468 PolarHBondContact O-N 3.45Å; Q468-G472 PolarHBondContact O-N 3.16Å
469Q88.5Confident84.4Confident0 Ų036.1 Ų36.10%018%0.184CC..Hα-helixtrans-67.7-43.1177.4-70.9-72.94.900112.3T29 E136 E444 E445 I465 Q467 G472 R473T29-Q469 PolarHBondContact OG1-OE1 2.89Å; E136-Q469 PolarHBondContact OE1-NE2 2.95Å; E136-Q469 PolarHBondContact OE2-NE2 3.49Å; E444-Q469 CarbonylContact O-C 3.51Å; E444-Q469 VanDerWaalsContact O-C 3.27Å; E444-Q469 WeakPolarHBondContact O-CB 3.48Å; E444-Q469 VanDerWaalsContact O-O 3.09Å; E445-Q469 HydrophobicContact CG-CB 3.98Å; E445-Q469 HydrophobicContact CG-CG 3.81Å; I465-Q469 HydrophobicContact CG2-CG 4.13Å; I465-Q469 WeakPolarHBondContact O-CB 3.41Å; I465-Q469 WeakPolarHBondContact O-CG 3.33Å; I465-Q469 PolarHBondContact O-N 3.17Å; Q467-Q469 VanDerWaalsContact C-N 3.32Å; Q467-Q469 PolarHBondContact O-N 3.1Å; Q469-G472 PolarHBondContact O-N 2.73Å; Q469-R473 PolarHBondContact O-NE 2.82Å; Q469-R473 VanDerWaalsContact O-NE 3.11Å
470A86.7Confident85.2Confident0 Ų037.1 Ų37.10%019%0.185CC..Hα-helixtrans-65-45.9175.100000111.6F377 E444 A466 Q467 G472 R473F377-A470 HydrophobicContact CD2-CB 4.21Å; F377-A470 HydrophobicContact CE2-CB 3.88Å; F377-A470 HydrophobicContact CZ-CB 4.46Å; E444-A470 HydrophobicContact CG-CB 4.28Å; A466-A470 WeakPolarHBondContact O-CB 3.36Å; A466-A470 PolarHBondContact O-N 3.49Å; Q467-A470 PolarHBondContact O-N 2.79Å; A470-G472 VanDerWaalsContact C-N 3.28Å; A470-G472 PolarHBondContact O-N 3.43Å; A470-R473 WeakPolarHBondContact O-CB 3.1Å; A470-R473 WeakPolarHBondContact O-CG 3.48Å; A470-R473 PolarHBondContact O-N 2.96Å
471S86.6Confident85.8Confident29 Ų2936.6 Ų36.620%0.20318%0.182CC..Hα-helixtrans-56.7-43.8175.7-179.20000111.4P217 Q467 R473 A474P217-S471 VanDerWaalsContact CG-OG 3.26Å; P217-S471 WeakPolarHBondContact CG-OG 3.42Å; Q467-S471 VanDerWaalsContact O-CB 3.32Å; Q467-S471 WeakPolarHBondContact O-CB 3.42Å; Q467-S471 PolarHBondContact O-N 3.39Å; S471-R473 PolarHBondContact O-N 3.06Å; S471-A474 PolarHBondContact O-N 2.85Å
472G84.4Confident86.3Confident13 Ų1333.5 Ų33.513%0.13417%0.166CC..THydrogen-bonded Turntrans-66.11.4176.500000116.3T29 Q468 Q469 A470 R475T29-G472 VanDerWaalsContact CG2-O 3.27Å; T29-G472 WeakPolarHBondContact CG2-O 3.3Å; Q468-G472 PolarHBondContact O-N 3.16Å; Q469-G472 PolarHBondContact O-N 2.73Å; A470-G472 VanDerWaalsContact C-N 3.28Å; A470-G472 PolarHBondContact O-N 3.43Å; G472-R475 VanDerWaalsContact O-CG 3.28Å; G472-R475 WeakPolarHBondContact O-CG 3.34Å; G472-R475 PolarHBondContact O-NE 3.27Å
473R86.3Confident86.6Confident10 Ų1032.5 Ų32.54%0.03816%0.16CC..THydrogen-bonded Turntrans-82.9-28.4168.5-54-60135.6-156-5.1112I375 E444 L447 C452 V455 Q469 A470 S471 R475I375-R473 HydrophobicContact CD1-CB 3.96Å; I375-R473 HydrophobicContact CD1-CG 4.36Å; E444-R473 PolarHBondContact O-NE 2.9Å; E444-R473 PolarHBondContact O-NH2 2.89Å; L447-R473 WeakPolarHBondContact O-CD 3.46Å; L447-R473 PolarHBondContact O-NH1 2.88Å; C452-R473 WeakPolarHBondContact CB-O 3.24Å; C452-R473 PolarHBondContact SG-O 3.28Å; V455-R473 HydrophobicContact CG2-CB 3.92Å; Q469-R473 PolarHBondContact O-NE 2.82Å; Q469-R473 VanDerWaalsContact O-NE 3.11Å; A470-R473 WeakPolarHBondContact O-CB 3.1Å; A470-R473 WeakPolarHBondContact O-CG 3.48Å; A470-R473 PolarHBondContact O-N 2.96Å; S471-R473 PolarHBondContact O-N 3.06Å; R473-R475 PolarHBondContact O-N 2.87Å
474A85Confident86.6Confident1 Ų129.2 Ų29.21%0.00814%0.142CC..  trans-78.8102.5169.400000108.7P217 C452 V455 S471P217-A474 HydrophobicContact CB-CB 3.83Å; P217-A474 HydrophobicContact CG-CB 4.13Å; C452-A474 WeakPolarHBondContact O-CA 3.39Å; V455-A474 HydrophobicContact CB-CB 4.32Å; V455-A474 HydrophobicContact CG2-CB 3.75Å; S471-A474 PolarHBondContact O-N 2.85Å
475R76.1Confident86.4Confident59 Ų5929 Ų2922%0.22314%0.142CC..  trans-123.7-14.3-173.4-59.7-171.6-163162.512.2114.2D448 C452 G472 R473D448-R475 IonicContact OD1-CZ 2.61Å; D448-R475 IonicContact OD1-NH1 3.34Å; D448-R475 PolarHBondContact OD1-NH1 3.38Å; D448-R475 IonicContact OD1-NH2 3.23Å; C452-R475 PolarHBondContact O-N 3.28Å; G472-R475 VanDerWaalsContact O-CG 3.28Å; G472-R475 WeakPolarHBondContact O-CG 3.34Å; G472-R475 PolarHBondContact O-NE 3.27Å; R473-R475 PolarHBondContact O-N 2.87Å
476A81.3Confident86.3Confident22 Ų2230 Ų3018%0.18215%0.146CC..SBendtrans-60.8153.2172.900000110.1P450 C452 N453 S479P450-A476 PolarHBondContact O-N 3.33Å; C452-A476 PolarHBondContact O-N 2.71Å; N453-A476 HydrophobicContact CB-CB 3.79Å; A476-S479 WeakPolarHBondContact O-CB 3.42Å; A476-S479 PolarHBondContact O-N 3.27Å; A476-S479 PolarHBondContact O-OG 3.09Å
477R75.2Confident86.2Confident214 Ų21435.5 Ų35.581%0.80817%0.169SC*.THydrogen-bonded Turntrans-58.5145.4167.2-70.4-175.7176.8-176.9-2.1108.9S479R477-S479 PolarHBondContact O-N 2.79Å; R477-S479 VanDerWaalsContact O-N 3.17Å
478D81.6Confident86Confident158 Ų15837.6 Ų37.685%0.84519%0.192SC*.THydrogen-bonded Turntrans58.925.1-177.8-47.9-47.7000114
479S88.2Confident85.8Confident3 Ų337 Ų372%0.02119%0.192CC..  trans-71.4146.2178.858.80000112.5P217 Q218 N453 A476 R477P217-S479 CarbonylContact C-O 3.4Å; P217-S479 WeakPolarHBondContact CA-O 3.3Å; P217-S479 WeakPolarHBondContact CB-O 3.38Å; Q218-S479 PolarHBondContact N-O 2.76Å; N453-S479 CarbonylContact O-C 3.58Å; N453-S479 WeakPolarHBondContact O-CA 3.28Å; N453-S479 WeakPolarHBondContact O-CB 3.45Å; A476-S479 WeakPolarHBondContact O-CB 3.42Å; A476-S479 PolarHBondContact O-N 3.27Å; A476-S479 PolarHBondContact O-OG 3.09Å; R477-S479 PolarHBondContact O-N 2.79Å; R477-S479 VanDerWaalsContact O-N 3.17Å
480Q91.6Very high85.5Confident34 Ų3441.7 Ų41.716%0.15921%0.21CC..EExtended strand (participates in β ladder)trans-111.3136.4-177-171.71771400111.1T220 N453 L454 V455T220-Q480 HydrophobicContact CG2-CG 4.43Å; T220-Q480 PolarHBondContact OG1-NE2 3.45Å; N453-Q480 PolarHBondContact O-N 2.65Å; L454-Q480 WeakPolarHBondContact CA-O 3.47Å; L454-Q480 HydrophobicContact CD1-CB 4.05Å; L454-Q480 HydrophobicContact CD1-CG 4.32Å; V455-Q480 PolarHBondContact N-O 3.39Å
481Y92.4Very high85.4Confident2 Ų242.5 Ų42.51%0.00821%0.214CC..EExtended strand (participates in β ladder)trans-115.7105.7169174.7-93.3000108.8Q218 K219 T220 V455 R457 Q467 V483 E495Q218-Y481 PolarHBondContact O-N 2.98Å; K219-Y481 CarbonylContact C-O 3.52Å; K219-Y481 VanDerWaalsContact CA-O 3.3Å; K219-Y481 WeakPolarHBondContact CA-O 3.36Å; K219-Y481 HydrophobicContact CB-CD1 4.21Å; K219-Y481 HydrophobicContact CD-CD1 3.89Å; K219-Y481 HydrophobicContact CD-CE1 3.93Å; K219-Y481 HydrophobicContact CG-CD1 3.81Å; K219-Y481 HydrophobicContact CG-CE1 4.25Å; T220-Y481 PolarHBondContact N-O 3Å; V455-Y481 HydrophobicContact CB-CD2 3.99Å; V455-Y481 HydrophobicContact CG1-CD2 3.72Å; V455-Y481 HydrophobicContact CG1-CE2 3.99Å; V455-Y481 CarbonylContact O-C 3.55Å; V455-Y481 WeakPolarHBondContact O-CA 3.4Å; R457-Y481 VanDerWaalsContact CD-CZ 3.45Å; R457-Y481 WeakPolarHBondContact CD-OH 3.31Å; R457-Y481 HydrophobicContact CG-CE2 3.95Å; R457-Y481 PolarHBondContact NH1-OH 3.16Å; R457-Y481 VanDerWaalsContact NH1-OH 3.09Å; Q467-Y481 WeakPolarHBondContact CG-OH 3.46Å; Y481-V483 HydrophobicContact CD1-CG2 4.26Å; Y481-V483 HydrophobicContact CE1-CG2 3.59Å; Y481-E495 WeakPolarHBondContact CE1-OE1 3.38Å; Y481-E495 PolarHBondContact OH-OE1 3.3Å
482S92.6Very high85.4Confident0 Ų041.7 Ų41.70%021%0.207CC..EExtended strand (participates in β ladder)trans-103.2133.2-174.6164.90000111.4D222 V455 V456 R457D222-S482 WeakPolarHBondContact OD2-CB 3.44Å; D222-S482 PolarHBondContact OD2-OG 3.29Å; V455-S482 PolarHBondContact O-N 2.96Å; V456-S482 WeakPolarHBondContact CA-O 3.39Å; R457-S482 PolarHBondContact N-O 3.26Å
483V90.6Very high85.6Confident6 Ų649 Ų494%0.03623%0.231CC..EExtended strand (participates in β ladder)trans-113.5104172.1-177.10000108.3T220 F221 D222 Y481 A485 E495T220-V483 PolarHBondContact O-N 3Å; F221-V483 HydrophobicContact CD1-CB 4.28Å; D222-V483 PolarHBondContact N-O 3.42Å; Y481-V483 HydrophobicContact CD1-CG2 4.26Å; Y481-V483 HydrophobicContact CE1-CG2 3.59Å; V483-A485 HydrophobicContact CG1-CB 4.45Å; V483-E495 HydrophobicContact CG1-CG 4.47Å; V483-E495 HydrophobicContact CG2-CG 4.08Å
484V88.5Confident85.7Confident1 Ų152 Ų521%0.00624%0.242CC..EExtended strand (participates in β ladder)trans-85.8117.3176.4-176.90000108.6D222 K354 K357 V456 R457 Y458D222-V484 HydrophobicContact CB-CG2 4.05Å; K354-V484 HydrophobicContact CB-CG1 4.3Å; K357-V484 HydrophobicContact CB-CG1 4.31Å; K357-V484 HydrophobicContact CG-CG1 4.24Å; V456-V484 HydrophobicContact CG1-CG2 3.9Å; R457-V484 PolarHBondContact O-N 2.87Å; Y458-V484 HydrophobicContact CD2-CB 3.82Å; Y458-V484 HydrophobicContact CD2-CG1 4.02Å; Y458-V484 HydrophobicContact CD2-CG2 4.25Å; Y458-V484 HydrophobicContact CE2-CB 4.16Å; Y458-V484 HydrophobicContact CE2-CG1 3.81Å
485A86.5Confident85.9Confident1 Ų152 Ų521%0.00824%0.242CC..EExtended strand (participates in β ladder)trans-150.1159.3-172.200000112.5D222 I223 V224 V483 E491 I492D222-A485 PolarHBondContact O-N 2.84Å; D222-A485 VanDerWaalsContact O-N 3.15Å; I223-A485 CarbonylContact C-O 2.96Å; I223-A485 VanDerWaalsContact CA-O 3.31Å; I223-A485 WeakPolarHBondContact CA-O 3.44Å; V224-A485 PolarHBondContact N-O 3.2Å; V483-A485 HydrophobicContact CG1-CB 4.45Å; A485-E491 HydrophobicContact CB-CB 3.79Å; A485-I492 HydrophobicContact CB-CD1 4.1Å; A485-I492 HydrophobicContact CB-CG1 3.4Å; A485-I492 VanDerWaalsContact CB-CG1 3.4Å
486Q86.6Confident86.6Confident37 Ų3754.9 Ų54.917%0.17325%0.254CS..EExtended strand (participates in β ladder)trans-84.6144.2174.8-172.5-179-41.200111.1V224 G488 G489 I492V224-Q486 HydrophobicContact CG2-CB 4.48Å; V224-Q486 CarbonylContact O-C 3.59Å; V224-Q486 WeakPolarHBondContact O-CA 3.24Å; Q486-G488 PolarHBondContact O-N 3.48Å; Q486-G489 WeakPolarHBondContact O-CA 3.36Å; Q486-G489 PolarHBondContact O-N 2.79Å; Q486-I492 WeakPolarHBondContact O-CD1 3.3Å
487K87Confident87.1Confident123 Ų12356.8 Ų56.854%0.53526%0.26SS..THydrogen-bonded Turntrans-55.5126.5175.1-169.4179.1-172.81780111.3I223 V224 E225 G489I223-K487 HydrophobicContact CG2-CB 3.63Å; I223-K487 HydrophobicContact CG2-CG 4.17Å; V224-K487 PolarHBondContact O-N 3.33Å; E225-K487 WeakPolarHBondContact OE1-CD 3.34Å; E225-K487 IonicContact OE1-NZ 2.76Å; E225-K487 PolarHBondContact OE1-NZ 3.01Å; E225-K487 VanDerWaalsContact OE2-CD 3.29Å; E225-K487 WeakPolarHBondContact OE2-CD 3.41Å; E225-K487 IonicContact OE2-NZ 3.83Å; K487-G489 PolarHBondContact O-N 3.13Å; K487-G489 VanDerWaalsContact O-N 3.12Å
488G83.5Confident87.9Confident50 Ų5046.6 Ų46.652%0.51522%0.222SC..THydrogen-bonded Turntrans67.63.4-175.700000114.7Q486Q486-G488 PolarHBondContact O-N 3.48Å
489G83Confident88.4Confident13 Ų1342.1 Ų42.113%0.13420%0.196CC..  trans-67.8168.4-179.100000113.6Q486 K487 E491Q486-G489 WeakPolarHBondContact O-CA 3.36Å; Q486-G489 PolarHBondContact O-N 2.79Å; K487-G489 PolarHBondContact O-N 3.13Å; K487-G489 VanDerWaalsContact O-N 3.12Å; G489-E491 VanDerWaalsContact C-N 3.27Å; G489-E491 PolarHBondContact O-N 2.79Å
490R82.7Confident88.7Confident99 Ų9947.2 Ų47.237%0.37422%0.215SC..Hα-helixtrans-68.3-30.9-177.3-68.2-175.6-75.9-169-7.8111.7E262 L461 R494E262-R490 IonicContact OE1-NH1 3.46Å; E262-R490 IonicContact OE2-NH1 3.55Å; E262-R490 PolarHBondContact OE2-NH1 3Å; L461-R490 HydrophobicContact CD1-CB 4.31Å; L461-R490 HydrophobicContact CD2-CB 4.15Å; L461-R490 WeakPolarHBondContact CD2-O 3.43Å; R490-R494 VanDerWaalsContact O-CB 3.29Å; R490-R494 WeakPolarHBondContact O-CB 3.42Å; R490-R494 PolarHBondContact O-N 2.73Å
491E83.6Confident88.9Confident17 Ų1745.7 Ų45.78%0.07921%0.208CC..Hα-helixtrans-63.7-48.1-177.6-55.595133.400111.3K354 L461 A485 G489 R494 E495K354-E491 IonicContact NZ-OE1 2.68Å; K354-E491 PolarHBondContact NZ-OE1 3.38Å; L461-E491 HydrophobicContact CD2-CB 4.36Å; L461-E491 HydrophobicContact CD2-CG 4.17Å; A485-E491 HydrophobicContact CB-CB 3.79Å; G489-E491 VanDerWaalsContact C-N 3.27Å; G489-E491 PolarHBondContact O-N 2.79Å; E491-R494 PolarHBondContact O-N 3.28Å; E491-E495 WeakPolarHBondContact O-CB 3.23Å; E491-E495 PolarHBondContact O-N 2.66Å
492I86.8Confident88.9Confident13 Ų1348.1 Ų48.17%0.06722%0.22CC..Hα-helixtrans-62.5-49.3177.9-57.4-178.1000110.6I223 A485 Q486 R494 E495 Y496I223-I492 HydrophobicContact CB-CD1 4.44Å; I223-I492 HydrophobicContact CD1-CD1 3.82Å; I223-I492 HydrophobicContact CG1-CD1 3.71Å; I223-I492 HydrophobicContact CG2-CD1 4.02Å; A485-I492 HydrophobicContact CB-CD1 4.1Å; A485-I492 HydrophobicContact CB-CG1 3.4Å; A485-I492 VanDerWaalsContact CB-CG1 3.4Å; Q486-I492 WeakPolarHBondContact O-CD1 3.3Å; I492-R494 VanDerWaalsContact C-N 3.25Å; I492-R494 PolarHBondContact O-N 2.94Å; I492-E495 PolarHBondContact O-N 3.44Å; I492-Y496 HydrophobicContact CG2-CD2 3.75Å; I492-Y496 HydrophobicContact CG2-CE2 3.29Å; I492-Y496 WeakPolarHBondContact O-CD2 3.41Å; I492-Y496 PolarHBondContact O-N 3.01Å
493R88.2Confident89Confident165 Ų16553.2 Ų53.262%0.62324%0.244SC*.Hα-helixtrans-58.5-41.6179.3-66.6179.9-173.5-176.11.6111.1I497R493-I497 WeakPolarHBondContact O-CD1 3.41Å; R493-I497 VanDerWaalsContact O-CG1 3.26Å; R493-I497 WeakPolarHBondContact O-CG1 3.11Å; R493-I497 PolarHBondContact O-N 3.37Å; R493-I497 VanDerWaalsContact O-N 3.09Å
494R89.3Confident89.3Confident73 Ų7353.3 Ų53.328%0.27524%0.244SC..Hα-helixtrans-66.7-40.4179.6-177.154.8176.81692.9111.9L461 T462 R490 E491 I492 I497 N498L461-R494 HydrophobicContact CD2-CB 3.64Å; L461-R494 HydrophobicContact CD2-CG 4.05Å; T462-R494 PolarHBondContact O-NE 2.87Å; T462-R494 PolarHBondContact O-NH2 2.83Å; T462-R494 VanDerWaalsContact O-NH2 3.14Å; R490-R494 VanDerWaalsContact O-CB 3.29Å; R490-R494 WeakPolarHBondContact O-CB 3.42Å; R490-R494 PolarHBondContact O-N 2.73Å; E491-R494 PolarHBondContact O-N 3.28Å; I492-R494 VanDerWaalsContact C-N 3.25Å; I492-R494 PolarHBondContact O-N 2.94Å; R494-I497 PolarHBondContact O-N 3.23Å; R494-N498 VanDerWaalsContact CZ-OD1 3.3Å; R494-N498 PolarHBondContact NE-OD1 3.37Å; R494-N498 VanDerWaalsContact O-CG 3.25Å; R494-N498 PolarHBondContact O-N 3.05Å
495E89.1Confident89.6Confident3 Ų353.3 Ų53.31%0.01424%0.244CC..Hα-helixtrans-66.2-40.7179.3-164.574.4-175.700112K219 F221 R457 Q467 Y481 V483 E491 I492 N498 E499K219-E495 WeakPolarHBondContact CE-OE1 3.3Å; K219-E495 IonicContact NZ-OE1 2.82Å; K219-E495 PolarHBondContact NZ-OE1 3.19Å; F221-E495 HydrophobicContact CE1-CB 3.93Å; F221-E495 HydrophobicContact CE1-CG 3.76Å; F221-E495 HydrophobicContact CZ-CB 4.47Å; F221-E495 HydrophobicContact CZ-CG 4.01Å; R457-E495 IonicContact CZ-OE2 3.77Å; R457-E495 IonicContact NH1-OE1 3.69Å; R457-E495 IonicContact NH1-OE2 3.42Å; R457-E495 PolarHBondContact NH1-OE2 3.37Å; Q467-E495 WeakPolarHBondContact CG-OE1 3.35Å; Q467-E495 PolarHBondContact OE1-OE1 2.87Å; Q467-E495 PolarHBondContact OE1-OE2 3.16Å; Q467-E495 VanDerWaalsContact OE1-OE2 3.13Å; Y481-E495 WeakPolarHBondContact CE1-OE1 3.38Å; Y481-E495 PolarHBondContact OH-OE1 3.3Å; V483-E495 HydrophobicContact CG1-CG 4.47Å; V483-E495 HydrophobicContact CG2-CG 4.08Å; E491-E495 WeakPolarHBondContact O-CB 3.23Å; E491-E495 PolarHBondContact O-N 2.66Å; I492-E495 PolarHBondContact O-N 3.44Å; E495-N498 PolarHBondContact O-N 3.07Å; E495-E499 PolarHBondContact O-N 3.03Å
496Y90.6Very high90Very high118 Ų11854.4 Ų54.446%0.46326%0.255SS..Hα-helixtrans-63.9-39.7172.2-71.6-48.6000112.8F221 I492 N498 E499 Y500F221-Y496 HydrophobicContact CE1-CE1 4.31Å; F221-Y496 AromaticContact CE2-CE1 3.96Å; F221-Y496 HydrophobicContact CE2-CE1 3.96Å; F221-Y496 HydrophobicContact CZ-CD1 4.11Å; F221-Y496 AromaticContact CZ-CE1 3.7Å; F221-Y496 HydrophobicContact CZ-CE1 3.7Å; I492-Y496 HydrophobicContact CG2-CD2 3.75Å; I492-Y496 HydrophobicContact CG2-CE2 3.29Å; I492-Y496 WeakPolarHBondContact O-CD2 3.41Å; I492-Y496 PolarHBondContact O-N 3.01Å; Y496-N498 VanDerWaalsContact C-N 3.3Å; Y496-N498 PolarHBondContact O-N 3.28Å; Y496-E499 PolarHBondContact O-N 3.47Å; Y496-Y500 PolarHBondContact O-N 3.49Å; Y496-Y500 VanDerWaalsContact O-N 3.11Å
497I92.1Very high90.5Very high62 Ų6257.7 Ų57.732%0.31827%0.269SS..Hα-helixtrans-60.4-44.8174.4-71.7164.9000109.9R493 R494 E499 Y500 L501R493-I497 WeakPolarHBondContact O-CD1 3.41Å; R493-I497 VanDerWaalsContact O-CG1 3.26Å; R493-I497 WeakPolarHBondContact O-CG1 3.11Å; R493-I497 PolarHBondContact O-N 3.37Å; R493-I497 VanDerWaalsContact O-N 3.09Å; R494-I497 PolarHBondContact O-N 3.23Å; I497-E499 PolarHBondContact O-N 3.46Å; I497-Y500 WeakPolarHBondContact O-CB 3.35Å; I497-Y500 PolarHBondContact O-N 2.94Å; I497-L501 HydrophobicContact CG2-CD1 3.98Å; I497-L501 HydrophobicContact CG2-CG 4.17Å; I497-L501 VanDerWaalsContact O-CG 3.27Å; I497-L501 WeakPolarHBondContact O-CG 3.31Å; I497-L501 PolarHBondContact O-N 3.45Å
498N92.4Very high91.1Very high0 Ų051.9 Ų51.90%024%0.243CC..Hα-helixtrans-65-36.8-179.3-73.1-12.9000112.6T462 E464 Q467 R494 E495 Y496 L501 E502T462-N498 PolarHBondContact O-ND2 2.55Å; T462-N498 VanDerWaalsContact O-ND2 3.1Å; T462-N498 PolarHBondContact O-OD1 2.83Å; E464-N498 HydrophobicContact CB-CB 4.16Å; E464-N498 PolarHBondContact N-OD1 3.34Å; Q467-N498 PolarHBondContact OE1-ND2 3.21Å; R494-N498 VanDerWaalsContact CZ-OD1 3.3Å; R494-N498 PolarHBondContact NE-OD1 3.37Å; R494-N498 VanDerWaalsContact O-CG 3.25Å; R494-N498 PolarHBondContact O-N 3.05Å; E495-N498 PolarHBondContact O-N 3.07Å; Y496-N498 VanDerWaalsContact C-N 3.3Å; Y496-N498 PolarHBondContact O-N 3.28Å; N498-L501 PolarHBondContact O-N 2.98Å; N498-E502 PolarHBondContact O-N 3.33Å
499E91.4Very high91.7Very high65 Ų6549.5 Ų49.530%0.30422%0.219SC..Hα-helixtrans-60.2-45.5171.6-72.8173.1175.600111.8K219 E495 Y496 I497 L501 E502 E503K219-E499 VanDerWaalsContact CD-OE1 3.31Å; K219-E499 WeakPolarHBondContact CD-OE1 2.99Å; K219-E499 WeakPolarHBondContact CE-OE1 3.47Å; K219-E499 IonicContact NZ-OE1 2.69Å; K219-E499 PolarHBondContact NZ-OE1 3.08Å; E495-E499 PolarHBondContact O-N 3.03Å; Y496-E499 PolarHBondContact O-N 3.47Å; I497-E499 PolarHBondContact O-N 3.46Å; E499-L501 VanDerWaalsContact C-N 3.32Å; E499-L501 PolarHBondContact O-N 3.25Å; E499-E502 WeakPolarHBondContact O-CB 3.37Å; E499-E502 PolarHBondContact O-N 3.11Å; E499-E503 PolarHBondContact O-N 2.98Å; E499-E503 VanDerWaalsContact O-N 3.15Å
500Y94.6Very high92.4Very high109 Ų10951.4 Ų51.443%0.42723%0.234SC..Hα-helixtrans-60.2-41.4173.7169-102.3000112.2K180 Y496 I497 E502 E503 L504K180-Y500 WeakPolarHBondContact O-CE1 3.34Å; K180-Y500 PolarHBondContact O-OH 2.98Å; K180-Y500 VanDerWaalsContact O-OH 3.09Å; Y496-Y500 PolarHBondContact O-N 3.49Å; Y496-Y500 VanDerWaalsContact O-N 3.11Å; I497-Y500 WeakPolarHBondContact O-CB 3.35Å; I497-Y500 PolarHBondContact O-N 2.94Å; Y500-E502 VanDerWaalsContact C-N 3.35Å; Y500-E503 PolarHBondContact O-N 3.35Å; Y500-L504 HydrophobicContact CE1-CD2 4.21Å; Y500-L504 WeakPolarHBondContact O-CB 3.35Å; Y500-L504 PolarHBondContact O-N 3.4Å
501L94.9Very high93.1Very high2 Ų252.3 Ų52.31%0.0124%0.237CC..Hα-helixtrans-68-32177.9-67.3-177.9000112.8T176 A179 E464 I497 N498 E499 L504 T505T176-L501 HydrophobicContact CG2-CB 4.28Å; T176-L501 HydrophobicContact CG2-CD2 4.27Å; T176-L501 WeakPolarHBondContact CG2-O 3.42Å; A179-L501 WeakPolarHBondContact O-CD2 3.42Å; E464-L501 HydrophobicContact CB-CB 3.9Å; E464-L501 HydrophobicContact CG-CB 3.97Å; I497-L501 HydrophobicContact CG2-CD1 3.98Å; I497-L501 HydrophobicContact CG2-CG 4.17Å; I497-L501 VanDerWaalsContact O-CG 3.27Å; I497-L501 WeakPolarHBondContact O-CG 3.31Å; I497-L501 PolarHBondContact O-N 3.45Å; N498-L501 PolarHBondContact O-N 2.98Å; E499-L501 VanDerWaalsContact C-N 3.32Å; E499-L501 PolarHBondContact O-N 3.25Å; L501-L504 HydrophobicContact CD2-CD2 4.19Å; L501-L504 PolarHBondContact O-N 3.41Å; L501-T505 WeakPolarHBondContact O-CB 3.09Å; L501-T505 PolarHBondContact O-N 3.44Å; L501-T505 PolarHBondContact O-OG1 2.88Å
502E92.9Very high93.8Very high53 Ų5351.8 Ų51.825%0.24824%0.235CC..Hα-helixtrans-63.8-46.3172.7-173.9-179.5159.500110.8R216 N498 E499 Y500 L504 T505 G506R216-E502 IonicContact NH1-OE1 3.57Å; N498-E502 PolarHBondContact O-N 3.33Å; E499-E502 WeakPolarHBondContact O-CB 3.37Å; E499-E502 PolarHBondContact O-N 3.11Å; Y500-E502 VanDerWaalsContact C-N 3.35Å; E502-L504 VanDerWaalsContact C-N 3.34Å; E502-L504 PolarHBondContact O-N 3.3Å; E502-T505 WeakPolarHBondContact O-CB 3.46Å; E502-T505 PolarHBondContact O-N 3.24Å; E502-G506 PolarHBondContact O-N 3.43Å; E502-G506 VanDerWaalsContact O-N 3.15Å
503E94.3Very high94.3Very high108 Ų10853.5 Ų53.551%0.50524%0.243SC..Hα-helixtrans-61.7-43.4174.4-168-164.4149.800111.6E499 Y500 T505 G506 K507E499-E503 PolarHBondContact O-N 2.98Å; E499-E503 VanDerWaalsContact O-N 3.15Å; Y500-E503 PolarHBondContact O-N 3.35Å; E503-T505 VanDerWaalsContact C-N 3.29Å; E503-T505 PolarHBondContact O-N 2.88Å; E503-G506 PolarHBondContact O-N 3.48Å; E503-K507 PolarHBondContact O-N 3.39Å; E503-K507 VanDerWaalsContact OE1-CE 3.23Å; E503-K507 WeakPolarHBondContact OE1-CE 3.41Å; E503-K507 IonicContact OE1-NZ 3.72Å; E503-K507 PolarHBondContact OE1-NZ 3.04Å
504L96.6Very high94.7Very high7 Ų749.3 Ų49.34%0.03724%0.239CC..Hα-helixtrans-61.8-38177.5-167.964.5000111.8T176 L182 A185 Y500 L501 E502 K507 A508T176-L504 HydrophobicContact CG2-CB 4.34Å; T176-L504 HydrophobicContact CG2-CD2 4.31Å; T176-L504 HydrophobicContact CG2-CG 4.46Å; L182-L504 HydrophobicContact CB-CD1 3.95Å; L182-L504 HydrophobicContact CD1-CD1 4.05Å; A185-L504 HydrophobicContact CB-CD2 4Å; A185-L504 HydrophobicContact CB-CG 3.92Å; Y500-L504 HydrophobicContact CE1-CD2 4.21Å; Y500-L504 WeakPolarHBondContact O-CB 3.35Å; Y500-L504 PolarHBondContact O-N 3.4Å; L501-L504 HydrophobicContact CD2-CD2 4.19Å; L501-L504 PolarHBondContact O-N 3.41Å; E502-L504 VanDerWaalsContact C-N 3.34Å; E502-L504 PolarHBondContact O-N 3.3Å; L504-K507 PolarHBondContact O-N 2.85Å; L504-A508 WeakPolarHBondContact O-CB 3.02Å; L504-A508 PolarHBondContact O-N 3.11Å
505T95.6Very high95Very high2 Ų246.9 Ų46.91%0.01223%0.231CC..Hα-helixtrans-60.7-46.7174.7-58.90000110.6P174 T176 L501 E502 E503 K507 A508 I509P174-T505 HydrophobicContact CG-CG2 3.9Å; T176-T505 VanDerWaalsContact CG2-OG1 3.23Å; T176-T505 WeakPolarHBondContact CG2-OG1 3.39Å; L501-T505 WeakPolarHBondContact O-CB 3.09Å; L501-T505 PolarHBondContact O-N 3.44Å; L501-T505 PolarHBondContact O-OG1 2.88Å; E502-T505 WeakPolarHBondContact O-CB 3.46Å; E502-T505 PolarHBondContact O-N 3.24Å; E503-T505 VanDerWaalsContact C-N 3.29Å; E503-T505 PolarHBondContact O-N 2.88Å; T505-K507 VanDerWaalsContact C-N 3.35Å; T505-K507 PolarHBondContact O-N 3.23Å; T505-A508 PolarHBondContact O-N 3.31Å; T505-I509 HydrophobicContact CG2-CD1 3.92Å; T505-I509 HydrophobicContact CG2-CG1 4.49Å; T505-I509 VanDerWaalsContact O-CG1 3.29Å; T505-I509 WeakPolarHBondContact O-CG1 3.45Å; T505-I509 PolarHBondContact O-N 3.46Å
506G95.7Very high95.4Very high24 Ų2450 Ų5025%0.24725%0.253CS..Hα-helixtrans-59.1-43.7176.400000112.9E502 E503 I509 A510E502-G506 PolarHBondContact O-N 3.43Å; E502-G506 VanDerWaalsContact O-N 3.15Å; E503-G506 PolarHBondContact O-N 3.48Å; G506-I509 PolarHBondContact O-N 3.39Å; G506-A510 PolarHBondContact O-N 3.07Å
507K97.3Very high95.7Very high106 Ų10649.7 Ų49.746%0.46126%0.256SS..Hα-helixtrans-62.9-42.9175.4-72.2171.3170.1168.10112.4L182 E503 L504 T505 A510 R511L182-K507 HydrophobicContact CD1-CB 3.7Å; E503-K507 PolarHBondContact O-N 3.39Å; E503-K507 VanDerWaalsContact OE1-CE 3.23Å; E503-K507 WeakPolarHBondContact OE1-CE 3.41Å; E503-K507 IonicContact OE1-NZ 3.72Å; E503-K507 PolarHBondContact OE1-NZ 3.04Å; L504-K507 PolarHBondContact O-N 2.85Å; T505-K507 VanDerWaalsContact C-N 3.35Å; T505-K507 PolarHBondContact O-N 3.23Å; K507-A510 PolarHBondContact O-N 3.06Å; K507-R511 PolarHBondContact O-N 3.32Å
508A97.9Very high95.9Very high0 Ų054 Ų540%027%0.274CS..Hα-helixtrans-63-44.3178.100000111.7L182 A185 V186 V189 L504 T505 R511 V512L182-A508 HydrophobicContact CD1-CB 4.25Å; A185-A508 HydrophobicContact CB-CB 3.91Å; V186-A508 HydrophobicContact CG2-CB 3.91Å; V189-A508 HydrophobicContact CG2-CB 3.97Å; L504-A508 WeakPolarHBondContact O-CB 3.02Å; L504-A508 PolarHBondContact O-N 3.11Å; T505-A508 PolarHBondContact O-N 3.31Å; A508-R511 WeakPolarHBondContact O-CB 3.32Å; A508-R511 PolarHBondContact O-N 3.33Å; A508-V512 WeakPolarHBondContact O-CG2 3.39Å; A508-V512 PolarHBondContact O-N 2.69Å
509I97.4Very high96.1Very high0 Ų056.6 Ų56.60%029%0.286CS..Hα-helixtrans-63-44.5177-64.4168.5000110.9W26 P174 V189 I200 T505 G506 R511 V512 Q513W26-I509 HydrophobicContact CD2-CD1 3.5Å; W26-I509 HydrophobicContact CE3-CB 4.24Å; W26-I509 HydrophobicContact CE3-CD1 3.5Å; W26-I509 VanDerWaalsContact CE3-CD1 3.5Å; W26-I509 HydrophobicContact CE3-CG1 4.44Å; W26-I509 HydrophobicContact CE3-CG2 3.61Å; W26-I509 HydrophobicContact CG-CD1 4.21Å; W26-I509 HydrophobicContact CH2-CD1 3.76Å; W26-I509 HydrophobicContact CZ2-CD1 3.73Å; W26-I509 HydrophobicContact CZ3-CB 3.99Å; W26-I509 HydrophobicContact CZ3-CD1 3.64Å; W26-I509 HydrophobicContact CZ3-CG1 4.44Å; W26-I509 HydrophobicContact CZ3-CG2 3.69Å; P174-I509 HydrophobicContact CG-CD1 3.58Å; P174-I509 HydrophobicContact CG-CG1 4.09Å; V189-I509 HydrophobicContact CG1-CG1 4.23Å; V189-I509 HydrophobicContact CG2-CG1 4.17Å; I200-I509 HydrophobicContact CD1-CD1 3.96Å; I200-I509 HydrophobicContact CD1-CG1 4.02Å; I200-I509 HydrophobicContact CD1-CG2 4.12Å; I200-I509 HydrophobicContact CG1-CG2 4.32Å; I200-I509 HydrophobicContact CG2-CG2 3.97Å; T505-I509 HydrophobicContact CG2-CD1 3.92Å; T505-I509 HydrophobicContact CG2-CG1 4.49Å; T505-I509 VanDerWaalsContact O-CG1 3.29Å; T505-I509 WeakPolarHBondContact O-CG1 3.45Å; T505-I509 PolarHBondContact O-N 3.46Å; G506-I509 PolarHBondContact O-N 3.39Å; I509-R511 VanDerWaalsContact C-N 3.26Å; I509-R511 PolarHBondContact O-N 2.95Å; I509-V512 PolarHBondContact O-N 3.38Å; I509-V512 VanDerWaalsContact O-N 3.16Å; I509-Q513 HydrophobicContact CG2-CG 4.12Å; I509-Q513 WeakPolarHBondContact O-CB 3.43Å; I509-Q513 WeakPolarHBondContact O-CG 3.29Å; I509-Q513 PolarHBondContact O-N 3.26Å
510A97Very high96.4Very high54 Ų5454.6 Ų54.645%0.44628%0.277SS..Hα-helixtrans-59.6-37.9176.200000112.1G506 K507 S514G506-A510 PolarHBondContact O-N 3.07Å; K507-A510 PolarHBondContact O-N 3.06Å; A510-S514 WeakPolarHBondContact O-CB 3.46Å; A510-S514 PolarHBondContact O-N 3.36Å; A510-S514 VanDerWaalsContact O-N 3.11Å; A510-S514 PolarHBondContact O-OG 2.95Å
511R97.7Very high96.5Very high117 Ų11756.5 Ų56.544%0.44228%0.283SS..Hα-helixtrans-66.4-41.9175.3-174.961.1172.4130.8-1.2112V186 K507 A508 I509 S514 M515V186-R511 HydrophobicContact CG1-CG 4.43Å; V186-R511 HydrophobicContact CG2-CB 3.84Å; V186-R511 HydrophobicContact CG2-CG 3.87Å; K507-R511 PolarHBondContact O-N 3.32Å; A508-R511 WeakPolarHBondContact O-CB 3.32Å; A508-R511 PolarHBondContact O-N 3.33Å; I509-R511 VanDerWaalsContact C-N 3.26Å; I509-R511 PolarHBondContact O-N 2.95Å; R511-S514 WeakPolarHBondContact CA-OG 3.22Å; R511-S514 PolarHBondContact O-N 2.89Å; R511-S514 PolarHBondContact O-OG 2.61Å; R511-M515 HydrophobicContact CG-CE 4.42Å; R511-M515 WeakPolarHBondContact O-CG 3.46Å; R511-M515 PolarHBondContact O-N 3.09Å
512V97.8Very high96.6Very high6 Ų662.1 Ų62.14%0.03630%0.304CS..Hα-helixtrans-66.4-43.2175.91730000111.2V186 V189 L190 I200 A508 I509 S514 M515 F520V186-V512 HydrophobicContact CG1-CG2 4.02Å; V189-V512 HydrophobicContact CB-CG2 4.15Å; V189-V512 HydrophobicContact CG1-CB 4.25Å; V189-V512 HydrophobicContact CG1-CG1 4.4Å; V189-V512 HydrophobicContact CG1-CG2 3.84Å; L190-V512 HydrophobicContact CD2-CG1 4.12Å; L190-V512 HydrophobicContact CD2-CG2 4.1Å; L190-V512 HydrophobicContact CG-CG2 4.01Å; I200-V512 HydrophobicContact CG2-CG1 4.2Å; A508-V512 WeakPolarHBondContact O-CG2 3.39Å; A508-V512 PolarHBondContact O-N 2.69Å; I509-V512 PolarHBondContact O-N 3.38Å; I509-V512 VanDerWaalsContact O-N 3.16Å; V512-S514 PolarHBondContact O-N 3.01Å; V512-M515 HydrophobicContact CG2-CE 4.3Å; V512-M515 WeakPolarHBondContact O-CB 3.49Å; V512-M515 PolarHBondContact O-N 3.25Å; V512-F520 HydrophobicContact CG1-CD2 4.14Å; V512-F520 HydrophobicContact CG1-CE2 3.85Å
513Q96.8Very high96.9Very high49 Ų4962 Ų6223%0.22930%0.303CS..Hα-helixtrans-67.9-19.6178.8-74.3-177.7-1400114.5I200 S202 I509I200-Q513 HydrophobicContact CG2-CG 4.14Å; I200-Q513 WeakPolarHBondContact O-CG 3.38Å; I200-Q513 PolarHBondContact O-NE2 3.4Å; I200-Q513 VanDerWaalsContact O-NE2 3.14Å; S202-Q513 PolarHBondContact OG-NE2 3.41Å; S202-Q513 PolarHBondContact OG-OE1 3.43Å; I509-Q513 HydrophobicContact CG2-CG 4.12Å; I509-Q513 WeakPolarHBondContact O-CB 3.43Å; I509-Q513 WeakPolarHBondContact O-CG 3.29Å; I509-Q513 PolarHBondContact O-N 3.26Å
514S96.7Very high97.1Very high78 Ų7857.2 Ų57.255%0.54528%0.281SS..THydrogen-bonded Turntrans-93.5-3.5175.453.50000113.6A510 R511 V512A510-S514 WeakPolarHBondContact O-CB 3.46Å; A510-S514 PolarHBondContact O-N 3.36Å; A510-S514 VanDerWaalsContact O-N 3.11Å; A510-S514 PolarHBondContact O-OG 2.95Å; R511-S514 WeakPolarHBondContact CA-OG 3.22Å; R511-S514 PolarHBondContact O-N 2.89Å; R511-S514 PolarHBondContact O-OG 2.61Å; V512-S514 PolarHBondContact O-N 3.01Å
515M97.3Very high97.1Very high21 Ų2160.4 Ų60.410%0.10330%0.298CS..SBendtrans-65144.8173.9-67.1-177.3-175.700110.7V186 L190 R511 V512 F520 K523V186-M515 HydrophobicContact CG1-CE 3.74Å; L190-M515 HydrophobicContact CD1-CE 4.2Å; L190-M515 HydrophobicContact CD2-SD 4.1Å; R511-M515 HydrophobicContact CG-CE 4.42Å; R511-M515 WeakPolarHBondContact O-CG 3.46Å; R511-M515 PolarHBondContact O-N 3.09Å; V512-M515 HydrophobicContact CG2-CE 4.3Å; V512-M515 WeakPolarHBondContact O-CB 3.49Å; V512-M515 PolarHBondContact O-N 3.25Å; M515-F520 HydrophobicContact CB-CB 4.43Å; M515-K523 HydrophobicContact SD-CD 4.34Å
516S97.5Very high97.2Very high69 Ų6964.4 Ų64.448%0.48332%0.317SS..  trans-63148.5169.571.60000110.1H518 E519 F520S516-H518 PolarHBondContact O-N 3.5Å; S516-E519 PolarHBondContact O-N 3.07Å; S516-E519 VanDerWaalsContact O-N 3.15Å; S516-E519 VanDerWaalsContact OG-CB 3.3Å; S516-E519 WeakPolarHBondContact OG-CB 3.48Å; S516-E519 PolarHBondContact OG-N 3.13Å; S516-F520 PolarHBondContact O-N 3.38Å
517E95Very high97.3Very high112 Ų11265.2 Ų65.252%0.52332%0.315SS..Hα-helixtrans-56.9-37.3179.1-178.6171.6-158.800112.3R521E517-R521 HydrophobicContact CG-CG 4.43Å; E517-R521 WeakPolarHBondContact O-CB 3.43Å; E517-R521 VanDerWaalsContact O-CG 3.26Å; E517-R521 WeakPolarHBondContact O-CG 3.41Å; E517-R521 PolarHBondContact O-N 3.47Å; E517-R521 IonicContact OE1-CZ 3.78Å; E517-R521 IonicContact OE1-NE 3.62Å; E517-R521 PolarHBondContact OE1-NE 3.02Å; E517-R521 IonicContact OE1-NH2 2.74Å; E517-R521 PolarHBondContact OE1-NH2 3.08Å
518H96.5Very high97.3Very high151 Ų15160.3 Ų60.370%0.69929%0.293SS*.Hα-helixtrans-65-47.5176.7-177.474.6000112.3S516 R522S516-H518 PolarHBondContact O-N 3.5Å; H518-R522 WeakPolarHBondContact O-CB 3.31Å; H518-R522 PolarHBondContact O-N 2.97Å
519E97.4Very high97.2Very high55 Ų5563.2 Ų63.226%0.25731%0.311SS..Hα-helixtrans-61.8-46177.9-174.5-168.816700111.3S516 R522 K523S516-E519 PolarHBondContact O-N 3.07Å; S516-E519 VanDerWaalsContact O-N 3.15Å; S516-E519 VanDerWaalsContact OG-CB 3.3Å; S516-E519 WeakPolarHBondContact OG-CB 3.48Å; S516-E519 PolarHBondContact OG-N 3.13Å; E519-R522 PolarHBondContact O-N 2.89Å; E519-K523 HydrophobicContact CG-CD 4.3Å; E519-K523 PolarHBondContact O-N 3.46Å; E519-K523 WeakPolarHBondContact OE1-CE 3.42Å; E519-K523 IonicContact OE1-NZ 2.71Å; E519-K523 PolarHBondContact OE1-NZ 3.48Å
520F97.6Very high97.2Very high24 Ų2469.6 Ų69.611%0.10534%0.341CS..Hα-helixtrans-58.9-54.2179.1-179.6-96.7000110.8L190 C193 V199 V512 M515 S516 R522 K523 I524L190-F520 HydrophobicContact CD2-CD2 4.02Å; L190-F520 HydrophobicContact CD2-CE2 4.05Å; C193-F520 HydrophobicContact CB-CE2 4.14Å; C193-F520 HydrophobicContact CB-CZ 3.95Å; V199-F520 HydrophobicContact CB-CZ 4.49Å; V199-F520 HydrophobicContact CG1-CD1 4.09Å; V199-F520 HydrophobicContact CG1-CE1 3.46Å; V199-F520 VanDerWaalsContact CG1-CE1 3.46Å; V199-F520 HydrophobicContact CG1-CZ 3.85Å; V512-F520 HydrophobicContact CG1-CD2 4.14Å; V512-F520 HydrophobicContact CG1-CE2 3.85Å; M515-F520 HydrophobicContact CB-CB 4.43Å; S516-F520 PolarHBondContact O-N 3.38Å; F520-R522 VanDerWaalsContact C-N 3.29Å; F520-R522 PolarHBondContact O-N 2.86Å; F520-K523 PolarHBondContact O-N 3.36Å; F520-I524 HydrophobicContact CD1-CG1 3.93Å; F520-I524 HydrophobicContact CD2-CG1 4.35Å; F520-I524 HydrophobicContact CE1-CD1 4.15Å; F520-I524 HydrophobicContact CE1-CG1 3.59Å; F520-I524 HydrophobicContact CE2-CD1 3.93Å; F520-I524 HydrophobicContact CE2-CG1 4.05Å; F520-I524 HydrophobicContact CG-CG1 4.31Å; F520-I524 HydrophobicContact CZ-CD1 3.68Å; F520-I524 HydrophobicContact CZ-CG1 3.65Å; F520-I524 VanDerWaalsContact O-CG1 3.27Å; F520-I524 WeakPolarHBondContact O-CG1 3.49Å; F520-I524 PolarHBondContact O-N 3.08Å
521R96.5Very high97Very high149 Ų14968.8 Ų68.856%0.56233%0.334SS*.Hα-helixtrans-57.7-40.2179.9-73.4175.9-180-160.8-0.5112.5E517 N525E517-R521 HydrophobicContact CG-CG 4.43Å; E517-R521 WeakPolarHBondContact O-CB 3.43Å; E517-R521 VanDerWaalsContact O-CG 3.26Å; E517-R521 WeakPolarHBondContact O-CG 3.41Å; E517-R521 PolarHBondContact O-N 3.47Å; E517-R521 IonicContact OE1-CZ 3.78Å; E517-R521 IonicContact OE1-NE 3.62Å; E517-R521 PolarHBondContact OE1-NE 3.02Å; E517-R521 IonicContact OE1-NH2 2.74Å; E517-R521 PolarHBondContact OE1-NH2 3.08Å; R521-N525 PolarHBondContact O-N 3.46Å; R521-N525 VanDerWaalsContact O-N 3.07Å; R521-N525 PolarHBondContact O-ND2 3.38Å
522R97.9Very high96.8Very high119 Ų11964.1 Ų64.145%0.44932%0.318SS..Hα-helixtrans-60.4-51.8176.5-174.3-177.666.989.5-4.4111.3H518 E519 F520 I524 N525 E526H518-R522 WeakPolarHBondContact O-CB 3.31Å; H518-R522 PolarHBondContact O-N 2.97Å; E519-R522 PolarHBondContact O-N 2.89Å; F520-R522 VanDerWaalsContact C-N 3.29Å; F520-R522 PolarHBondContact O-N 2.86Å; R522-I524 PolarHBondContact O-N 3.24Å; R522-N525 PolarHBondContact O-N 3.37Å; R522-E526 WeakPolarHBondContact CG-OE1 3.5Å; R522-E526 IonicContact CZ-OE1 3.57Å; R522-E526 IonicContact NH1-OE1 2.76Å; R522-E526 PolarHBondContact NH1-OE1 3.38Å; R522-E526 IonicContact NH1-OE2 2.73Å; R522-E526 PolarHBondContact NH1-OE2 2.81Å; R522-E526 WeakPolarHBondContact O-CG 3.47Å; R522-E526 PolarHBondContact O-N 3.02Å
523K98Very high96.5Very high51 Ų5168.6 Ų68.622%0.22234%0.341CS..Hα-helixtrans-61.4-42.3179.4-74.8178.1167.5173.70112.3L190 M515 E519 F520 N525 E526 I527L190-K523 HydrophobicContact CD1-CD 3.88Å; M515-K523 HydrophobicContact SD-CD 4.34Å; E519-K523 HydrophobicContact CG-CD 4.3Å; E519-K523 PolarHBondContact O-N 3.46Å; E519-K523 WeakPolarHBondContact OE1-CE 3.42Å; E519-K523 IonicContact OE1-NZ 2.71Å; E519-K523 PolarHBondContact OE1-NZ 3.48Å; F520-K523 PolarHBondContact O-N 3.36Å; K523-N525 PolarHBondContact O-N 3.19Å; K523-E526 PolarHBondContact O-N 3.24Å; K523-I527 VanDerWaalsContact O-CG1 3.28Å; K523-I527 WeakPolarHBondContact O-CG1 3.33Å; K523-I527 PolarHBondContact O-N 3.39Å
524I98Very high96.3Very high7 Ų771.8 Ų71.84%0.03636%0.357CS..Hα-helixtrans-60.3-47177.4-65.5-60.9000111.4C193 A194 F520 R522 E526 I527 Q528C193-I524 HydrophobicContact CB-CD1 3.72Å; A194-I524 HydrophobicContact CB-CD1 3.81Å; A194-I524 HydrophobicContact CB-CG2 4.3Å; F520-I524 HydrophobicContact CD1-CG1 3.93Å; F520-I524 HydrophobicContact CD2-CG1 4.35Å; F520-I524 HydrophobicContact CE1-CD1 4.15Å; F520-I524 HydrophobicContact CE1-CG1 3.59Å; F520-I524 HydrophobicContact CE2-CD1 3.93Å; F520-I524 HydrophobicContact CE2-CG1 4.05Å; F520-I524 HydrophobicContact CG-CG1 4.31Å; F520-I524 HydrophobicContact CZ-CD1 3.68Å; F520-I524 HydrophobicContact CZ-CG1 3.65Å; F520-I524 VanDerWaalsContact O-CG1 3.27Å; F520-I524 WeakPolarHBondContact O-CG1 3.49Å; F520-I524 PolarHBondContact O-N 3.08Å; R522-I524 PolarHBondContact O-N 3.24Å; I524-E526 PolarHBondContact O-N 3.47Å; I524-I527 PolarHBondContact O-N 2.92Å; I524-Q528 HydrophobicContact CG2-CG 4.31Å; I524-Q528 WeakPolarHBondContact O-CB 3.36Å; I524-Q528 VanDerWaalsContact O-CG 3.3Å; I524-Q528 WeakPolarHBondContact O-CG 3.46Å; I524-Q528 PolarHBondContact O-N 3.01Å
525N97.1Very high95.9Very high74 Ų7469.7 Ų69.740%0.39634%0.34SS..Hα-helixtrans-64.1-39178.7-73.7-22.5000112.5R521 R522 K523 T529R521-N525 PolarHBondContact O-N 3.46Å; R521-N525 VanDerWaalsContact O-N 3.07Å; R521-N525 PolarHBondContact O-ND2 3.38Å; R522-N525 PolarHBondContact O-N 3.37Å; K523-N525 PolarHBondContact O-N 3.19Å; N525-T529 WeakPolarHBondContact O-CB 3.33Å; N525-T529 PolarHBondContact O-N 3.2Å; N525-T529 PolarHBondContact O-OG1 3.3Å
526E97.8Very high95.5Very high87 Ų8774.2 Ų74.241%0.40736%0.359SS..Hα-helixtrans-60.5-50.4175.3-74.5169-171.700111.2R522 K523 I524 T529 Q530R522-E526 WeakPolarHBondContact CG-OE1 3.5Å; R522-E526 IonicContact CZ-OE1 3.57Å; R522-E526 IonicContact NH1-OE1 2.76Å; R522-E526 PolarHBondContact NH1-OE1 3.38Å; R522-E526 IonicContact NH1-OE2 2.73Å; R522-E526 PolarHBondContact NH1-OE2 2.81Å; R522-E526 WeakPolarHBondContact O-CG 3.47Å; R522-E526 PolarHBondContact O-N 3.02Å; K523-E526 PolarHBondContact O-N 3.24Å; I524-E526 PolarHBondContact O-N 3.47Å; E526-T529 PolarHBondContact O-N 2.96Å; E526-Q530 WeakPolarHBondContact O-CG 3.28Å; E526-Q530 PolarHBondContact O-N 2.92Å
527I97.8Very high95.2Very high40 Ų4073.8 Ų73.821%0.20535%0.353CS..Hα-helixtrans-62.4-46.9179.3-64.9165.5000110.9L190 A194 K523 I524 T529 Q530 A531L190-I527 HydrophobicContact CB-CD1 3.92Å; A194-I527 HydrophobicContact CB-CB 3.76Å; A194-I527 HydrophobicContact CB-CD1 4.28Å; A194-I527 HydrophobicContact CB-CG2 3.48Å; A194-I527 VanDerWaalsContact CB-CG2 3.48Å; K523-I527 VanDerWaalsContact O-CG1 3.28Å; K523-I527 WeakPolarHBondContact O-CG1 3.33Å; K523-I527 PolarHBondContact O-N 3.39Å; I524-I527 PolarHBondContact O-N 2.92Å; I527-T529 PolarHBondContact O-N 3.46Å; I527-Q530 PolarHBondContact O-N 2.77Å; I527-A531 WeakPolarHBondContact O-CB 3.31Å; I527-A531 PolarHBondContact O-N 3.41Å
528Q97.8Very high94.9Very high3 Ų371.7 Ų71.71%0.01435%0.345CS..Hα-helixtrans-59-45.5178.6-77.9177.7-1000111.7V154 A194 D197 I524 A531 I532V154-Q528 HydrophobicContact CG1-CB 3.69Å; V154-Q528 HydrophobicContact CG1-CG 3.79Å; V154-Q528 HydrophobicContact CG2-CG 4.2Å; A194-Q528 HydrophobicContact CB-CG 4.23Å; A194-Q528 WeakPolarHBondContact O-CG 3.31Å; A194-Q528 PolarHBondContact O-NE2 3.24Å; D197-Q528 PolarHBondContact OD1-NE2 3.45Å; I524-Q528 HydrophobicContact CG2-CG 4.31Å; I524-Q528 WeakPolarHBondContact O-CB 3.36Å; I524-Q528 VanDerWaalsContact O-CG 3.3Å; I524-Q528 WeakPolarHBondContact O-CG 3.46Å; I524-Q528 PolarHBondContact O-N 3.01Å; Q528-A531 PolarHBondContact O-N 3.36Å; Q528-I532 WeakPolarHBondContact O-CG1 3.49Å; Q528-I532 PolarHBondContact O-N 3.5Å; Q528-I532 VanDerWaalsContact O-N 3.14Å
529T96.6Very high94.4Very high61 Ų6168.5 Ų68.537%0.37433%0.33SS..Hα-helixtrans-63.8-46.5-179.8-57.10000111.2N525 E526 I527 A531 I532 I533N525-T529 WeakPolarHBondContact O-CB 3.33Å; N525-T529 PolarHBondContact O-N 3.2Å; N525-T529 PolarHBondContact O-OG1 3.3Å; E526-T529 PolarHBondContact O-N 2.96Å; I527-T529 PolarHBondContact O-N 3.46Å; T529-A531 PolarHBondContact O-N 2.91Å; T529-I532 PolarHBondContact O-N 3.27Å; T529-I533 HydrophobicContact CG2-CD1 4Å; T529-I533 WeakPolarHBondContact O-CG1 3.31Å; T529-I533 PolarHBondContact O-N 3.16Å; T529-I533 VanDerWaalsContact O-N 3.1Å
530Q95.5Very high93.9Very high135 Ų13570.5 Ų70.563%0.63134%0.343SS*.Hα-helixtrans-61.7-42.4177.2-73.3-179.8-8.500112.1E526 I527 I532 I533 M534E526-Q530 WeakPolarHBondContact O-CG 3.28Å; E526-Q530 PolarHBondContact O-N 2.92Å; I527-Q530 PolarHBondContact O-N 2.77Å; Q530-I532 VanDerWaalsContact C-N 3.34Å; Q530-I532 PolarHBondContact O-N 2.95Å; Q530-I533 PolarHBondContact O-N 2.91Å; Q530-M534 WeakPolarHBondContact O-CB 3.37Å; Q530-M534 PolarHBondContact O-N 2.93Å
531A93.6Very high93.5Very high37 Ų3777 Ų7731%0.30637%0.367SS..Hα-helixtrans-61-41178.900000112.4I527 Q528 T529 N535I527-A531 WeakPolarHBondContact O-CB 3.31Å; I527-A531 PolarHBondContact O-N 3.41Å; Q528-A531 PolarHBondContact O-N 3.36Å; T529-A531 PolarHBondContact O-N 2.91Å; A531-N535 WeakPolarHBondContact O-CB 3.34Å; A531-N535 PolarHBondContact O-N 3.15Å
532I92.7Very high93Very high18 Ų1874.3 Ų74.39%0.09236%0.359CS..Hα-helixtrans-68.2-44.5177.2-65.9-59.4000111.6V154 E155 L158 Q528 T529 Q530 N535 K536V154-I532 HydrophobicContact CG1-CD1 4.28Å; V154-I532 HydrophobicContact CG1-CG1 4.06Å; E155-I532 HydrophobicContact CB-CD1 4.08Å; L158-I532 HydrophobicContact CD1-CG1 4.03Å; Q528-I532 WeakPolarHBondContact O-CG1 3.49Å; Q528-I532 PolarHBondContact O-N 3.5Å; Q528-I532 VanDerWaalsContact O-N 3.14Å; T529-I532 PolarHBondContact O-N 3.27Å; Q530-I532 VanDerWaalsContact C-N 3.34Å; Q530-I532 PolarHBondContact O-N 2.95Å; I532-N535 PolarHBondContact O-N 3.22Å; I532-K536 PolarHBondContact O-N 3.04Å; I532-K536 VanDerWaalsContact O-N 3.08Å
533I92.9Very high92.4Very high100 Ų10072.2 Ų72.251%0.51336%0.36SS..Hα-helixtrans-60.5-49.4177.2-67.2167.9000110.3T529 Q530 N535 K536 V537T529-I533 HydrophobicContact CG2-CD1 4Å; T529-I533 WeakPolarHBondContact O-CG1 3.31Å; T529-I533 PolarHBondContact O-N 3.16Å; T529-I533 VanDerWaalsContact O-N 3.1Å; Q530-I533 PolarHBondContact O-N 2.91Å; I533-N535 VanDerWaalsContact C-N 3.29Å; I533-N535 PolarHBondContact O-N 3.19Å; I533-K536 PolarHBondContact O-N 3.42Å; I533-V537 WeakPolarHBondContact O-CG2 3.32Å; I533-V537 PolarHBondContact O-N 2.72Å; I533-V537 VanDerWaalsContact O-N 3.12Å
534M91.4Very high91.9Very high117 Ų11776.2 Ų76.258%0.57638%0.379SS*.Hα-helixtrans-59.6-41179.2-175.263.473.100111.6Q530 V537 L538Q530-M534 WeakPolarHBondContact O-CB 3.37Å; Q530-M534 PolarHBondContact O-N 2.93Å; M534-V537 PolarHBondContact O-N 3.28Å; M534-L538 HydrophobicContact CG-CD1 4.05Å; M534-L538 HydrophobicContact CG-CG 4.44Å; M534-L538 WeakPolarHBondContact O-CB 3.49Å; M534-L538 VanDerWaalsContact O-CG 3.27Å; M534-L538 WeakPolarHBondContact O-CG 3.34Å; M534-L538 PolarHBondContact O-N 2.87Å; M534-L538 HydrophobicContact SD-CG 4.49Å
535N89.1Confident91.3Very high33 Ų3380.7 Ų80.718%0.17640%0.398CS..Hα-helixtrans-61.8-45.6176.9-173.54.4000111.5A531 I532 I533 V537 L538 Q539A531-N535 WeakPolarHBondContact O-CB 3.34Å; A531-N535 PolarHBondContact O-N 3.15Å; I532-N535 PolarHBondContact O-N 3.22Å; I533-N535 VanDerWaalsContact C-N 3.29Å; I533-N535 PolarHBondContact O-N 3.19Å; N535-V537 PolarHBondContact O-N 2.87Å; N535-L538 PolarHBondContact O-N 3.37Å; N535-L538 VanDerWaalsContact O-N 3.15Å; N535-Q539 WeakPolarHBondContact O-CG 3.19Å; N535-Q539 PolarHBondContact O-N 2.52Å; N535-Q539 PolarHBondContact OD1-NE2 2.87Å
536K88.8Confident90.7Very high116 Ų11681.4 Ų81.450%0.50440%0.398SS..Hα-helixtrans-56.2-50.8176.6-71.3-179.2179.2-177.10111.6I532 I533 L538 Q539 D540I532-K536 PolarHBondContact O-N 3.04Å; I532-K536 VanDerWaalsContact O-N 3.08Å; I533-K536 PolarHBondContact O-N 3.42Å; K536-L538 VanDerWaalsContact C-N 3.29Å; K536-L538 PolarHBondContact O-N 3.41Å; K536-Q539 PolarHBondContact O-N 3.34Å; K536-D540 VanDerWaalsContact O-CG 3.3Å; K536-D540 PolarHBondContact O-N 2.91Å
537V91.7Very high90.2Very high60 Ų6082 Ų8236%0.36440%0.404SS..Hα-helixtrans-58.2-40.8176.9175.80000112I533 M534 N535 D540 R541I533-V537 WeakPolarHBondContact O-CG2 3.32Å; I533-V537 PolarHBondContact O-N 2.72Å; I533-V537 VanDerWaalsContact O-N 3.12Å; M534-V537 PolarHBondContact O-N 3.28Å; N535-V537 PolarHBondContact O-N 2.87Å; V537-D540 PolarHBondContact O-N 3.4Å; V537-R541 WeakPolarHBondContact O-CG 3.45Å; V537-R541 PolarHBondContact O-N 3.11Å
538L88.1Confident89.9Confident69 Ų6987.6 Ų87.636%0.36142%0.422SS..Hα-helixtrans-68.9-32.6177.2-73.1172.8000113M534 N535 K536 K542M534-L538 HydrophobicContact CG-CD1 4.05Å; M534-L538 HydrophobicContact CG-CG 4.44Å; M534-L538 WeakPolarHBondContact O-CB 3.49Å; M534-L538 VanDerWaalsContact O-CG 3.27Å; M534-L538 WeakPolarHBondContact O-CG 3.34Å; M534-L538 PolarHBondContact O-N 2.87Å; M534-L538 HydrophobicContact SD-CG 4.49Å; N535-L538 PolarHBondContact O-N 3.37Å; N535-L538 VanDerWaalsContact O-N 3.15Å; K536-L538 VanDerWaalsContact C-N 3.29Å; K536-L538 PolarHBondContact O-N 3.41Å; L538-K542 VanDerWaalsContact O-CG 3.26Å; L538-K542 WeakPolarHBondContact O-CG 3.39Å; L538-K542 PolarHBondContact O-N 2.95Å; L538-K542 VanDerWaalsContact O-N 3.13Å
539Q86.2Confident89.6Confident83 Ų8388.7 Ų88.739%0.38843%0.427SS..Hα-helixtrans-69.1-43.7173.4-65.7-60-2100110.8N535 K536 R541 K542 T543N535-Q539 WeakPolarHBondContact O-CG 3.19Å; N535-Q539 PolarHBondContact O-N 2.52Å; N535-Q539 PolarHBondContact OD1-NE2 2.87Å; K536-Q539 PolarHBondContact O-N 3.34Å; Q539-R541 PolarHBondContact O-N 2.97Å; Q539-K542 WeakPolarHBondContact O-CB 3.5Å; Q539-K542 PolarHBondContact O-N 3.18Å; Q539-K542 VanDerWaalsContact O-N 3.08Å; Q539-T543 PolarHBondContact O-N 2.81Å; Q539-T543 PolarHBondContact O-OG1 3.44Å; Q539-T543 VanDerWaalsContact O-OG1 3.06Å
540D87.9Confident89.5Confident97 Ų9788.6 Ų88.652%0.51943%0.433SS..Hα-helixtrans-59-48.1178-62.3-22.2000110.7K536 V537 K542 T543 E544K536-D540 VanDerWaalsContact O-CG 3.3Å; K536-D540 PolarHBondContact O-N 2.91Å; V537-D540 PolarHBondContact O-N 3.4Å; D540-K542 VanDerWaalsContact C-N 3.31Å; D540-K542 PolarHBondContact O-N 2.96Å; D540-T543 WeakPolarHBondContact O-CB 3.38Å; D540-T543 PolarHBondContact O-N 3.36Å; D540-T543 VanDerWaalsContact O-N 3.11Å; D540-E544 WeakPolarHBondContact O-CG 3.44Å; D540-E544 PolarHBondContact O-N 3.23Å
541R88.4Confident89.4Confident162 Ų16283.3 Ų83.361%0.61141%0.412SS*.Hα-helixtrans-60.5-35.2174.5-73.3-179.1179.2-177.70.9113.7V537 Q539 K545V537-R541 WeakPolarHBondContact O-CG 3.45Å; V537-R541 PolarHBondContact O-N 3.11Å; Q539-R541 PolarHBondContact O-N 2.97Å; R541-K545 WeakPolarHBondContact O-CB 3.45Å; R541-K545 PolarHBondContact O-N 3.01Å
542K85.6Confident89.5Confident92 Ų9285.6 Ų85.640%0.443%0.426SS..Hα-helixtrans-67.8-40.7175.7-79170.2-173.9168.20110.8L538 Q539 D540 K545 K546L538-K542 VanDerWaalsContact O-CG 3.26Å; L538-K542 WeakPolarHBondContact O-CG 3.39Å; L538-K542 PolarHBondContact O-N 2.95Å; L538-K542 VanDerWaalsContact O-N 3.13Å; Q539-K542 WeakPolarHBondContact O-CB 3.5Å; Q539-K542 PolarHBondContact O-N 3.18Å; Q539-K542 VanDerWaalsContact O-N 3.08Å; D540-K542 VanDerWaalsContact C-N 3.31Å; D540-K542 PolarHBondContact O-N 2.96Å; K542-K545 PolarHBondContact O-N 3.24Å; K542-K546 WeakPolarHBondContact O-CG 3.03Å; K542-K546 PolarHBondContact O-N 3.19Å
543T85Confident89.6Confident75 Ų7587.1 Ų87.146%0.4644%0.438SS..Hα-helixtrans-65-46.7176.7-56.10000110.6Q539 D540 K545 K546 N547Q539-T543 PolarHBondContact O-N 2.81Å; Q539-T543 PolarHBondContact O-OG1 3.44Å; Q539-T543 VanDerWaalsContact O-OG1 3.06Å; D540-T543 WeakPolarHBondContact O-CB 3.38Å; D540-T543 PolarHBondContact O-N 3.36Å; D540-T543 VanDerWaalsContact O-N 3.11Å; T543-K545 VanDerWaalsContact C-N 3.35Å; T543-K545 PolarHBondContact O-N 3.47Å; T543-K546 PolarHBondContact O-N 2.91Å; T543-N547 WeakPolarHBondContact O-CB 3.28Å; T543-N547 PolarHBondContact O-N 3.26Å; T543-N547 PolarHBondContact O-ND2 3.15Å
544E87.1Confident89.8Confident135 Ų13582.4 Ų82.463%0.63141%0.414SS*.Hα-helixtrans-56.8-46.7173.3-72.8174.4173.400111.8D540 K546 N547 R548D540-E544 WeakPolarHBondContact O-CG 3.44Å; D540-E544 PolarHBondContact O-N 3.23Å; E544-K546 VanDerWaalsContact C-N 3.33Å; E544-K546 PolarHBondContact O-N 2.92Å; E544-N547 CarbonylContact O-C 3.59Å; E544-N547 PolarHBondContact O-N 3.29Å; E544-N547 VanDerWaalsContact O-N 3.08Å; E544-R548 PolarHBondContact O-N 2.85Å; E544-R548 VanDerWaalsContact O-N 3.15Å
545K85.8Confident90.1Very high100 Ų10082.5 Ų82.544%0.43541%0.408SS..Hα-helixtrans-61-41.4178.5-175.2-178.1173.3-169.60112.2R541 K542 T543 N547 R548 D658 P660R541-K545 WeakPolarHBondContact O-CB 3.45Å; R541-K545 PolarHBondContact O-N 3.01Å; K542-K545 PolarHBondContact O-N 3.24Å; T543-K545 VanDerWaalsContact C-N 3.35Å; T543-K545 PolarHBondContact O-N 3.47Å; K545-N547 PolarHBondContact O-N 3.25Å; K545-R548 WeakPolarHBondContact O-CB 3.46Å; K545-R548 PolarHBondContact O-N 2.93Å; K545-D658 VanDerWaalsContact CE-O 3.29Å; K545-D658 WeakPolarHBondContact CE-O 3.41Å; K545-D658 PolarHBondContact NZ-O 2.9Å; K545-P660 CarbonylContact O-C 3.43Å; K545-P660 WeakPolarHBondContact O-CA 3.34Å
546K85.6Confident90.5Very high90 Ų9080.9 Ų80.939%0.39140%0.399SS..Hα-helixtrans-68-24.6176.3-76.3-178.9175.1-171.40112.6K542 T543 E544 F661 M662K542-K546 WeakPolarHBondContact O-CG 3.03Å; K542-K546 PolarHBondContact O-N 3.19Å; T543-K546 PolarHBondContact O-N 2.91Å; E544-K546 VanDerWaalsContact C-N 3.33Å; E544-K546 PolarHBondContact O-N 2.92Å; K546-F661 CarbonylContact O-C 3.5Å; K546-F661 WeakPolarHBondContact O-CA 3.49Å; K546-M662 PolarHBondContact O-N 3.34Å
547N87.6Confident90.9Very high98 Ų9875.7 Ų75.752%0.52438%0.377SS..THydrogen-bonded Turntrans-99.112.1-179.8-64.1-13.7000112.6T543 E544 K545T543-N547 WeakPolarHBondContact O-CB 3.28Å; T543-N547 PolarHBondContact O-N 3.26Å; T543-N547 PolarHBondContact O-ND2 3.15Å; E544-N547 CarbonylContact O-C 3.59Å; E544-N547 PolarHBondContact O-N 3.29Å; E544-N547 VanDerWaalsContact O-N 3.08Å; K545-N547 PolarHBondContact O-N 3.25Å
548R89.8Confident91.2Very high159 Ų15972.8 Ų72.860%0.636%0.36SS*.SBendtrans-67.8-38.4-175.8-172.2-177.5178.3135-1.3112.6E544 K545 D648E544-R548 PolarHBondContact O-N 2.85Å; E544-R548 VanDerWaalsContact O-N 3.15Å; K545-R548 WeakPolarHBondContact O-CB 3.46Å; K545-R548 PolarHBondContact O-N 2.93Å; R548-D648 IonicContact CZ-OD2 2.79Å; R548-D648 IonicContact NE-OD2 3.13Å; R548-D648 PolarHBondContact NE-OD2 3.03Å; R548-D648 IonicContact NH2-OD2 2.66Å; R548-D648 PolarHBondContact NH2-OD2 3.24Å
549H93.2Very high91.5Very high26 Ų2671.4 Ų71.412%0.1235%0.35CS..SBendtrans-133.9148.7-179.7-55.3-57.7000111I554 D648 P660 F661H549-I554 HydrophobicContact CB-CD1 3.71Å; H549-I554 HydrophobicContact CB-CG1 4.32Å; H549-D648 IonicContact CE1-OD1 2.65Å; H549-D648 IonicContact CE1-OD2 3.64Å; H549-D648 PolarHBondContact CE1-OD2 3.22Å; H549-D648 VanDerWaalsContact CE1-OD2 3.28Å; H549-D648 IonicContact NE2-OD2 3.24Å; H549-D648 PolarHBondContact NE2-OD2 3.01Å; H549-P660 PolarHBondContact N-O 3.36Å; H549-F661 WeakPolarHBondContact O-CB 3.45Å
550A93.4Very high91.8Very high59 Ų5967.8 Ų67.849%0.48833%0.333SS..  trans-65.6140.7168.400000109.9S552 S553A550-S552 PolarHBondContact O-N 2.96Å; A550-S553 PolarHBondContact O-N 3.42Å; A550-S553 PolarHBondContact O-OG 3.42Å
551A93.8Very high92.1Very high23 Ų2364.1 Ų64.119%0.1932%0.315CS..G310 helixtrans-58.1-34.7-179.800000112.4S553 I554 G568 S569 F661A551-S553 VanDerWaalsContact C-N 3.29Å; A551-S553 PolarHBondContact O-N 3.12Å; A551-I554 PolarHBondContact O-N 3.36Å; A551-G568 CarbonylContact O-C 3.56Å; A551-G568 WeakPolarHBondContact O-CA 3.09Å; A551-G568 PolarHBondContact O-N 3.17Å; A551-S569 PolarHBondContact O-N 3.06Å; A551-F661 HydrophobicContact CB-CD2 3.6Å; A551-F661 HydrophobicContact CB-CE2 4.18Å; A551-F661 HydrophobicContact CB-CG 4.37Å
552S94.8Very high92.4Very high85 Ų8557.5 Ų57.559%0.59429%0.29SS*.G310 helixtrans-70-18.8177.654.90000114.6A550 I554A550-S552 PolarHBondContact O-N 2.96Å; S552-I554 VanDerWaalsContact C-N 3.32Å
553S95.6Very high92.9Very high51 Ų5154.2 Ų54.236%0.35728%0.28SS..G310 helixtrans-88.9-1.317671.40000113.2A550 A551A550-S553 PolarHBondContact O-N 3.42Å; A550-S553 PolarHBondContact O-OG 3.42Å; A551-S553 VanDerWaalsContact C-N 3.29Å; A551-S553 PolarHBondContact O-N 3.12Å
554I96.9Very high93.4Very high0 Ų055.1 Ų55.10%028%0.279CS..PPolyproline II helixtrans-99.5122.9178.3-55.2-53.4000109.3H549 A551 S552 I556 S567 G568 L644 E645 T646 F661H549-I554 HydrophobicContact CB-CD1 3.71Å; H549-I554 HydrophobicContact CB-CG1 4.32Å; A551-I554 PolarHBondContact O-N 3.36Å; S552-I554 VanDerWaalsContact C-N 3.32Å; I554-I556 HydrophobicContact CG2-CD1 3.96Å; I554-S567 CarbonylContact O-C 3.5Å; I554-G568 PolarHBondContact O-N 2.62Å; I554-L644 HydrophobicContact CG2-CB 4.15Å; I554-L644 HydrophobicContact CG2-CD2 4.45Å; I554-E645 WeakPolarHBondContact CA-O 3.34Å; I554-T646 HydrophobicContact CD1-CG2 3.83Å; I554-F661 HydrophobicContact CB-CD1 4.32Å; I554-F661 HydrophobicContact CB-CE1 4.47Å; I554-F661 HydrophobicContact CG1-CB 4.27Å; I554-F661 HydrophobicContact CG1-CD1 3.82Å; I554-F661 HydrophobicContact CG1-CE1 4.44Å; I554-F661 HydrophobicContact CG1-CG 4.2Å; I554-F661 HydrophobicContact CG2-CD1 4.26Å; I554-F661 HydrophobicContact CG2-CE1 4.08Å
555R97.6Very high93.9Very high119 Ų11949.2 Ų49.245%0.44925%0.252SS..EExtended strand (participates in β ladder)trans-99.2132.1172-56-179.5-73.1162.9-8.9110E564 E645R555-E564 HydrophobicContact CB-CG 4.36Å; R555-E564 WeakPolarHBondContact CD-OE2 3.4Å; R555-E564 IonicContact NH1-OE2 3.61Å; R555-E564 PolarHBondContact NH1-OE2 2.75Å; R555-E564 VanDerWaalsContact NH1-OE2 3.15Å; R555-E645 HydrophobicContact CB-CB 4.05Å; R555-E645 PolarHBondContact N-O 3Å; R555-E645 PolarHBondContact O-N 3.43Å
556I97.5Very high94.4Very high0 Ų044.7 Ų44.70%023%0.234CC..EExtended strand (participates in β ladder)trans-95.6123.3179.1-49.8-59.3000108I554 V565 A566 F571 F642 L644I554-I556 HydrophobicContact CG2-CD1 3.96Å; I556-V565 HydrophobicContact CB-CG2 4.33Å; I556-V565 HydrophobicContact CG2-CG2 4.03Å; I556-V565 VanDerWaalsContact O-CG2 3.24Å; I556-V565 WeakPolarHBondContact O-CG2 3.49Å; I556-V565 PolarHBondContact O-N 3.45Å; I556-A566 WeakPolarHBondContact CA-O 3.37Å; I556-A566 HydrophobicContact CB-CB 4.13Å; I556-A566 WeakPolarHBondContact CB-O 3.43Å; I556-A566 HydrophobicContact CG1-CB 4.32Å; I556-A566 PolarHBondContact N-O 3Å; I556-A566 PolarHBondContact O-N 3.25Å; I556-F571 HydrophobicContact CG1-CD2 4.42Å; I556-F571 HydrophobicContact CG1-CE2 3.76Å; I556-F642 HydrophobicContact CG2-CB 3.79Å; I556-F642 HydrophobicContact CG2-CD1 3.57Å; I556-F642 HydrophobicContact CG2-CE1 4.33Å; I556-F642 HydrophobicContact CG2-CG 3.75Å; I556-L644 HydrophobicContact CD1-CD2 3.23Å
557L97.8Very high95Very high6 Ų641.6 Ų41.63%0.03122%0.224CC..EExtended strand (participates in β ladder)trans-116.1142.9-176.2-57.3173.8000110.2R559 A563 E564 F642 A643 E645 R650L557-R559 PolarHBondContact O-N 3.31Å; L557-A563 CarbonylContact C-O 3.48Å; L557-A563 WeakPolarHBondContact CA-O 3.34Å; L557-E564 VanDerWaalsContact CD2-CA 3.46Å; L557-E564 HydrophobicContact CD2-CB 3.68Å; L557-E564 HydrophobicContact CD2-CG 4.12Å; L557-F642 CarbonylContact O-C 3.59Å; L557-F642 WeakPolarHBondContact O-CA 3.48Å; L557-F642 WeakPolarHBondContact O-CB 3.23Å; L557-A643 HydrophobicContact CB-CB 4.27Å; L557-A643 PolarHBondContact N-O 2.94Å; L557-A643 PolarHBondContact O-N 2.89Å; L557-E645 HydrophobicContact CD1-CB 4.1Å; L557-R650 HydrophobicContact CD1-CG 4.43Å; L557-R650 VanDerWaalsContact CD1-NE 3.26Å
558C96.9Very high95.4Very high0 Ų037 Ų370%020%0.199CC..EExtended strand (participates in β ladder)trans-62.3123.8170.1-178.50000110.3N560 F562 A563 V565 C618 W622C558-N560 PolarHBondContact O-N 2.99Å; C558-F562 WeakPolarHBondContact O-CA 3.47Å; C558-F562 PolarHBondContact O-N 3Å; C558-A563 PolarHBondContact N-O 3Å; C558-V565 HydrophobicContact CB-CG1 4.29Å; C558-C618 VanDerWaalsContact SG-SG 3.7Å; C558-W622 HydrophobicContact CB-CZ2 3.75Å; C558-W622 PolarHBondContact SG-NE1 3.12Å
559R95Very high95.6Very high40 Ų4032 Ų3215%0.15119%0.188CC..THydrogen-bonded Turntrans-63.2-18.8-177.6-172.1173.9-179.7149.510.9114.3E271 V275 L557 F562 K640 N641E271-R559 VanDerWaalsContact CD-NH2 3.28Å; E271-R559 IonicContact OE1-CZ 3.64Å; E271-R559 VanDerWaalsContact OE1-CZ 3.32Å; E271-R559 IonicContact OE1-NE 3.99Å; E271-R559 PolarHBondContact OE1-NE 2.96Å; E271-R559 IonicContact OE1-NH2 2.73Å; E271-R559 PolarHBondContact OE1-NH2 3Å; E271-R559 IonicContact OE2-CZ 2.79Å; E271-R559 IonicContact OE2-NE 2.79Å; E271-R559 IonicContact OE2-NH2 3.86Å; E271-R559 PolarHBondContact OE2-NH2 3.31Å; V275-R559 HydrophobicContact CG2-CG 4.12Å; L557-R559 PolarHBondContact O-N 3.31Å; R559-F562 VanDerWaalsContact O-CE1 3.24Å; R559-F562 WeakPolarHBondContact O-CE1 3.26Å; R559-K640 VanDerWaalsContact CD-O 3.22Å; R559-K640 WeakPolarHBondContact CD-O 3.33Å; R559-K640 PolarHBondContact NH1-O 3.34Å; R559-N641 WeakPolarHBondContact CB-O 3.37Å; R559-N641 PolarHBondContact N-O 3.37Å; R559-N641 VanDerWaalsContact N-O 3.12Å
560N93.2Very high95.8Very high6 Ų631.8 Ų31.83%0.03219%0.188CC..THydrogen-bonded Turntrans-95.5-37.8-175.4-169.766.6000114.2R280 Q284 C558 C618 K620R280-N560 PolarHBondContact NE-O 2.97Å; Q284-N560 PolarHBondContact NE2-O 3.43Å; Q284-N560 PolarHBondContact NE2-OD1 3.28Å; C558-N560 PolarHBondContact O-N 2.99Å; N560-C618 PolarHBondContact ND2-SG 3.4Å; N560-K620 HydrophobicContact CB-CB 3.79Å; N560-K620 HydrophobicContact CB-CD 3.99Å; N560-K620 HydrophobicContact CB-CG 3.84Å
561C93.9Very high95.9Very high21 Ų2129.2 Ų29.214%0.14217%0.166CC..THydrogen-bonded Turntrans-119.60.4-177.969.40000113.9I323 A563 N615 C618I323-C561 HydrophobicContact CD1-CB 3.94Å; C561-A563 PolarHBondContact O-N 2.88Å; C561-N615 PolarHBondContact SG-ND2 2.88Å; C561-N615 VanDerWaalsContact SG-ND2 3.42Å; C561-C618 HydrophobicContact CB-CB 3.91Å; C561-C618 VanDerWaalsContact CB-SG 3.6Å
562F95.1Very high96Very high23 Ų2329.9 Ų29.910%0.10117%0.165CC..  trans57.29-179.9-53.2-30.5000116.5V275 D278 R280 A283 C558 R559V275-F562 HydrophobicContact CB-CE1 4.27Å; V275-F562 HydrophobicContact CB-CZ 4.37Å; V275-F562 HydrophobicContact CG1-CE1 3.99Å; V275-F562 HydrophobicContact CG2-CE1 4.01Å; V275-F562 HydrophobicContact CG2-CZ 4.17Å; D278-F562 WeakPolarHBondContact OD1-CD2 3.39Å; R280-F562 HydrophobicContact CB-CD2 4.18Å; R280-F562 HydrophobicContact CB-CE2 3.73Å; R280-F562 HydrophobicContact CB-CZ 4.47Å; R280-F562 HydrophobicContact CG-CE2 4.44Å; A283-F562 HydrophobicContact CB-CZ 4.32Å; C558-F562 WeakPolarHBondContact O-CA 3.47Å; C558-F562 PolarHBondContact O-N 3Å; R559-F562 VanDerWaalsContact O-CE1 3.24Å; R559-F562 WeakPolarHBondContact O-CE1 3.26Å
563A95.6Very high95.9Very high23 Ų2327.1 Ų27.119%0.1914%0.143CC..  trans-61.8138.2171.300000110.6L557 C558 C561 V565 N615L557-A563 CarbonylContact C-O 3.48Å; L557-A563 WeakPolarHBondContact CA-O 3.34Å; C558-A563 PolarHBondContact N-O 3Å; C561-A563 PolarHBondContact O-N 2.88Å; A563-V565 WeakPolarHBondContact O-CG1 3.15Å; A563-N615 HydrophobicContact CB-CB 4.02Å
564E96.3Very high95.5Very high93 Ų9324.9 Ų24.944%0.43513%0.127SC..EExtended strand (participates in β ladder)trans-71.3131.3172.8-171.5175.7150.400110.4R555 L557R555-E564 HydrophobicContact CB-CG 4.36Å; R555-E564 WeakPolarHBondContact CD-OE2 3.4Å; R555-E564 IonicContact NH1-OE2 3.61Å; R555-E564 PolarHBondContact NH1-OE2 2.75Å; R555-E564 VanDerWaalsContact NH1-OE2 3.15Å; L557-E564 VanDerWaalsContact CD2-CA 3.46Å; L557-E564 HydrophobicContact CD2-CB 3.68Å; L557-E564 HydrophobicContact CD2-CG 4.12Å
565V96.6Very high94.6Very high11 Ų1129.1 Ų29.17%0.06715%0.147CC..EExtended strand (participates in β ladder)trans-127.6-26.6-170.4-62.10000113.6I556 C558 A563 F586 W622 F642I556-V565 HydrophobicContact CB-CG2 4.33Å; I556-V565 HydrophobicContact CG2-CG2 4.03Å; I556-V565 VanDerWaalsContact O-CG2 3.24Å; I556-V565 WeakPolarHBondContact O-CG2 3.49Å; I556-V565 PolarHBondContact O-N 3.45Å; C558-V565 HydrophobicContact CB-CG1 4.29Å; A563-V565 WeakPolarHBondContact O-CG1 3.15Å; V565-F586 HydrophobicContact CB-CE2 4.24Å; V565-F586 VanDerWaalsContact O-CD2 3.26Å; V565-F586 WeakPolarHBondContact O-CD2 3.38Å; V565-F586 VanDerWaalsContact O-CE2 3.29Å; V565-F586 WeakPolarHBondContact O-CE2 3.34Å; V565-W622 HydrophobicContact CB-CH2 3.87Å; V565-W622 HydrophobicContact CB-CZ2 4.42Å; V565-W622 HydrophobicContact CB-CZ3 4.37Å; V565-W622 HydrophobicContact CG1-CH2 3.28Å; V565-W622 HydrophobicContact CG1-CZ2 3.63Å; V565-W622 HydrophobicContact CG1-CZ3 4.22Å; V565-W622 HydrophobicContact CG2-CH2 4.38Å; V565-F642 HydrophobicContact CG2-CD1 3.95Å; V565-F642 HydrophobicContact CG2-CE1 3.85Å
566A96.9Very high93.6Very high6 Ų629.2 Ų29.25%0.0516%0.156CC..EExtended strand (participates in β ladder)trans-162164.2179.700000111.3I556 F571 F586I556-A566 WeakPolarHBondContact CA-O 3.37Å; I556-A566 HydrophobicContact CB-CB 4.13Å; I556-A566 WeakPolarHBondContact CB-O 3.43Å; I556-A566 HydrophobicContact CG1-CB 4.32Å; I556-A566 PolarHBondContact N-O 3Å; I556-A566 PolarHBondContact O-N 3.25Å; A566-F571 HydrophobicContact CB-CE2 3.77Å; A566-F571 HydrophobicContact CB-CZ 4.18Å; A566-F586 HydrophobicContact CB-CD2 4.13Å; A566-F586 HydrophobicContact CB-CE2 4.01Å
567S97.1Very high92.7Very high25 Ų2532.1 Ų32.118%0.17518%0.18CC..EExtended strand (participates in β ladder)trans-88153.3162.6172.70000110.5I554 S569 D570 F571I554-S567 CarbonylContact O-C 3.5Å; S567-S569 WeakPolarHBondContact CB-OG 3.26Å; S567-S569 PolarHBondContact O-N 3.18Å; S567-S569 PolarHBondContact OG-N 2.93Å; S567-S569 PolarHBondContact OG-OG 3.09Å; S567-D570 PolarHBondContact N-OD2 2.92Å; S567-D570 WeakPolarHBondContact O-CB 3.22Å; S567-D570 PolarHBondContact O-N 3.06Å; S567-D570 VanDerWaalsContact O-N 3.13Å; S567-F571 WeakPolarHBondContact O-CD2 3.22Å
568G95.6Very high92.3Very high1 Ų133.4 Ų33.41%0.0119%0.186CC..G310 helixtrans-59.6-29.1170.100000112.7A551 I554 D570 F571 F661A551-G568 CarbonylContact O-C 3.56Å; A551-G568 WeakPolarHBondContact O-CA 3.09Å; A551-G568 PolarHBondContact O-N 3.17Å; I554-G568 PolarHBondContact O-N 2.62Å; G568-D570 PolarHBondContact O-N 3.2Å; G568-F571 PolarHBondContact O-N 2.82Å; G568-F661 WeakPolarHBondContact O-CE2 3.43Å
569S95.4Very high92.2Very high53 Ų5335.4 Ų35.437%0.37119%0.194SC..G310 helixtrans-68.3-17.8176.259.60000114.1A551 S567 F571A551-S569 PolarHBondContact O-N 3.06Å; S567-S569 WeakPolarHBondContact CB-OG 3.26Å; S567-S569 PolarHBondContact O-N 3.18Å; S567-S569 PolarHBondContact OG-N 2.93Å; S567-S569 PolarHBondContact OG-OG 3.09Å; S569-F571 PolarHBondContact O-N 3.32Å
570D96Very high92.2Very high23 Ų2333.5 Ų33.512%0.12319%0.187CC..G310 helixtrans-75.1-10.5179.4-60.3-32.6000112.4S567 G568 N581 V582 N583S567-D570 PolarHBondContact N-OD2 2.92Å; S567-D570 WeakPolarHBondContact O-CB 3.22Å; S567-D570 PolarHBondContact O-N 3.06Å; S567-D570 VanDerWaalsContact O-N 3.13Å; G568-D570 PolarHBondContact O-N 3.2Å; D570-N581 VanDerWaalsContact CB-ND2 3.32Å; D570-N581 WeakPolarHBondContact CB-ND2 3.25Å; D570-N581 CarbonylContact O-C 3.55Å; D570-N581 WeakPolarHBondContact O-CA 3.49Å; D570-V582 WeakPolarHBondContact O-CG2 3.44Å; D570-V582 PolarHBondContact O-N 3.25Å; D570-N583 HydrophobicContact CB-CB 3.95Å; D570-N583 PolarHBondContact OD1-ND2 3.41Å
571F96.3Very high92.3Very high4 Ų433.3 Ų33.32%0.01819%0.186CC..EExtended strand (participates in β ladder)trans-98.4134.1-174.6-69.4-87.5000112.4I556 A566 S567 G568 S569 V580 N581 L637 W656 V663I556-F571 HydrophobicContact CG1-CD2 4.42Å; I556-F571 HydrophobicContact CG1-CE2 3.76Å; A566-F571 HydrophobicContact CB-CE2 3.77Å; A566-F571 HydrophobicContact CB-CZ 4.18Å; S567-F571 WeakPolarHBondContact O-CD2 3.22Å; G568-F571 PolarHBondContact O-N 2.82Å; S569-F571 PolarHBondContact O-N 3.32Å; F571-V580 CarbonylContact C-O 3.51Å; F571-V580 VanDerWaalsContact CA-O 3.31Å; F571-V580 WeakPolarHBondContact CA-O 3.29Å; F571-N581 HydrophobicContact CD1-CB 4.39Å; F571-N581 HydrophobicContact CE1-CB 4.02Å; F571-N581 HydrophobicContact CZ-CB 4.33Å; F571-L637 HydrophobicContact CE1-CB 4.15Å; F571-L637 HydrophobicContact CE1-CD1 3.56Å; F571-L637 HydrophobicContact CE1-CG 4.06Å; F571-L637 HydrophobicContact CZ-CD1 3.67Å; F571-W656 HydrophobicContact CB-CH2 4.25Å; F571-W656 HydrophobicContact CB-CZ3 4.39Å; F571-W656 AromaticContact CD1-CH2 3.34Å; F571-W656 HydrophobicContact CD1-CH2 3.34Å; F571-W656 AromaticContact CD1-CZ2 3.86Å; F571-W656 HydrophobicContact CD1-CZ2 3.86Å; F571-W656 HydrophobicContact CD1-CZ3 4.26Å; F571-W656 HydrophobicContact CD2-CH2 4.18Å; F571-W656 AromaticContact CE1-CH2 3.63Å; F571-W656 HydrophobicContact CE1-CH2 3.63Å; F571-W656 AromaticContact CE1-CZ2 3.94Å; F571-W656 HydrophobicContact CE1-CZ2 3.94Å; F571-W656 HydrophobicContact CE2-CH2 4.45Å; F571-W656 AromaticContact CG-CH2 3.63Å; F571-W656 HydrophobicContact CG-CH2 3.63Å; F571-W656 HydrophobicContact CG-CZ3 4.18Å; F571-W656 HydrophobicContact CZ-CH2 4.19Å; F571-V663 HydrophobicContact CB-CG1 4.39Å; F571-V663 WeakPolarHBondContact O-CG1 3.45Å
572K95.4Very high92.4Very high38 Ų3833.6 Ų33.617%0.16519%0.187CC..EExtended strand (participates in β ladder)trans-124.7152.5172-57.4-63.9-173.5-170.90111.1Y579 V580 V582 E664 F666K572-Y579 WeakPolarHBondContact O-CA 3.46Å; K572-V580 HydrophobicContact CB-CG2 4.31Å; K572-V580 PolarHBondContact N-O 2.77Å; K572-V580 WeakPolarHBondContact O-CG2 3.48Å; K572-V580 PolarHBondContact O-N 3.48Å; K572-V582 HydrophobicContact CB-CG1 4.2Å; K572-V582 HydrophobicContact CG-CG1 3.82Å; K572-V582 HydrophobicContact CG-CG2 3.98Å; K572-E664 CarbonylContact C-O 3.55Å; K572-E664 VanDerWaalsContact CA-O 3.3Å; K572-E664 WeakPolarHBondContact CA-O 3.35Å; K572-E664 HydrophobicContact CD-CB 3.95Å; K572-E664 IonicContact NZ-OE2 3.84Å; K572-E664 PolarHBondContact NZ-OE2 3.07Å; K572-F666 HydrophobicContact CB-CB 3.81Å; K572-F666 HydrophobicContact CB-CD2 4.24Å
573L93Very high92.2Very high26 Ų2634.9 Ų34.914%0.13620%0.195CC..EExtended strand (participates in β ladder)trans-93.8111176.6179.660.3000109.9H578 Y579 V663 E664 F666L573-H578 CarbonylContact C-O 3.18Å; L573-H578 WeakPolarHBondContact CA-O 3.38Å; L573-Y579 HydrophobicContact CD1-CD1 4.3Å; L573-Y579 HydrophobicContact CD1-CD2 4.16Å; L573-Y579 HydrophobicContact CD1-CE1 3.91Å; L573-Y579 HydrophobicContact CD1-CE2 3.74Å; L573-Y579 HydrophobicContact CD1-CG 4.42Å; L573-V663 HydrophobicContact CB-CG1 4.18Å; L573-E664 PolarHBondContact N-O 2.63Å; L573-F666 PolarHBondContact O-N 3.22Å
574L87.9Confident91.9Very high4 Ų437 Ų372%0.02121%0.206CC..EExtended strand (participates in β ladder)trans-97.6131.3176.9176.669.1000110.5N576 A577 H578 V580 M626 Y628 F666L574-N576 PolarHBondContact O-N 3.12Å; L574-N576 VanDerWaalsContact O-N 3.07Å; L574-A577 PolarHBondContact O-N 2.89Å; L574-H578 HydrophobicContact CB-CB 4.14Å; L574-H578 PolarHBondContact N-O 3.39Å; L574-H578 PolarHBondContact O-N 3.23Å; L574-V580 HydrophobicContact CB-CG1 4.4Å; L574-V580 HydrophobicContact CB-CG2 4.15Å; L574-V580 HydrophobicContact CD2-CG1 4.2Å; L574-M626 HydrophobicContact CD2-CE 3.8Å; L574-M626 HydrophobicContact CD2-SD 4.43Å; L574-Y628 HydrophobicContact CD1-CD2 3.94Å; L574-Y628 HydrophobicContact CD1-CE2 3.62Å; L574-Y628 HydrophobicContact CD2-CD2 3.77Å; L574-Y628 HydrophobicContact CD2-CE2 4.22Å; L574-Y628 HydrophobicContact CD2-CG 4.42Å; L574-Y628 HydrophobicContact CG-CD2 4.4Å; L574-Y628 HydrophobicContact CG-CE2 4.37Å; L574-F666 HydrophobicContact CB-CB 4.19Å; L574-F666 HydrophobicContact CD1-CB 4.25Å; L574-F666 HydrophobicContact CD1-CD1 3.43Å; L574-F666 VanDerWaalsContact CD1-CD1 3.43Å; L574-F666 HydrophobicContact CD1-CE1 4.05Å; L574-F666 HydrophobicContact CD1-CG 4.06Å
575E78.5Confident91.7Very high89 Ų8937.3 Ų37.342%0.41621%0.211SC..THydrogen-bonded Turntrans49.833.2178-64.6178.5-172.700114.2A577E575-A577 PolarHBondContact O-N 2.93Å
576N74.7Confident91.6Very high122 Ų12237 Ų3765%0.65221%0.209SC*.THydrogen-bonded Turntrans56.814.4-177.1-71.2-52.2000115.6L574L574-N576 PolarHBondContact O-N 3.12Å; L574-N576 VanDerWaalsContact O-N 3.07Å
577A79.5Confident91.4Very high61 Ų6143 Ų4350%0.50423%0.234SC..THydrogen-bonded Turntrans-137.5-36-171.800000114.1L574 E575L574-A577 PolarHBondContact O-N 2.89Å; E575-A577 PolarHBondContact O-N 2.93Å
578H88.8Confident91.2Very high32 Ų3246.2 Ų46.215%0.14825%0.249CC..EExtended strand (participates in β ladder)trans-106.6135.1-169.9-60.9-75.9000110.7L573 L574 W605 M626L573-H578 CarbonylContact C-O 3.18Å; L573-H578 WeakPolarHBondContact CA-O 3.38Å; L574-H578 HydrophobicContact CB-CB 4.14Å; L574-H578 PolarHBondContact N-O 3.39Å; L574-H578 PolarHBondContact O-N 3.23Å; H578-W605 AromaticContact CE1-CZ2 3.73Å; H578-W605 AromaticContact NE2-CZ2 3.76Å; H578-M626 HydrophobicContact CB-CE 3.91Å; H578-M626 HydrophobicContact CB-SD 3.75Å
579Y94.7Very high91.2Very high43 Ų4352.8 Ų52.817%0.16927%0.273CS..EExtended strand (participates in β ladder)trans-112.6100.7-177.6-68.7-100.8000107.8K572 L573 N636 L637 W656 V663K572-Y579 WeakPolarHBondContact O-CA 3.46Å; L573-Y579 HydrophobicContact CD1-CD1 4.3Å; L573-Y579 HydrophobicContact CD1-CD2 4.16Å; L573-Y579 HydrophobicContact CD1-CE1 3.91Å; L573-Y579 HydrophobicContact CD1-CE2 3.74Å; L573-Y579 HydrophobicContact CD1-CG 4.42Å; Y579-N636 PolarHBondContact N-OD1 3.12Å; Y579-N636 VanDerWaalsContact N-OD1 3.15Å; Y579-N636 WeakPolarHBondContact O-CA 3.35Å; Y579-N636 PolarHBondContact O-OD1 3.31Å; Y579-L637 PolarHBondContact O-N 3.31Å; Y579-L637 VanDerWaalsContact O-N 3.09Å; Y579-W656 HydrophobicContact CD1-CB 3.8Å; Y579-W656 AromaticContact CD1-CD2 3.4Å; Y579-W656 HydrophobicContact CD1-CD2 3.4Å; Y579-W656 AromaticContact CD1-CE2 3.97Å; Y579-W656 AromaticContact CD1-CE3 3.53Å; Y579-W656 HydrophobicContact CD1-CE3 3.53Å; Y579-W656 AromaticContact CD1-CG 3.56Å; Y579-W656 HydrophobicContact CD1-CG 3.56Å; Y579-W656 HydrophobicContact CD1-CZ3 4.21Å; Y579-W656 HydrophobicContact CD2-CB 3.79Å; Y579-W656 AromaticContact CD2-CD1 3.28Å; Y579-W656 HydrophobicContact CD2-CD2 4.03Å; Y579-W656 AromaticContact CD2-CG 3.45Å; Y579-W656 HydrophobicContact CD2-CG 3.45Å; Y579-W656 VanDerWaalsContact CD2-CG 3.45Å; Y579-W656 AromaticContact CD2-NE1 3.78Å; Y579-W656 HydrophobicContact CE1-CB 3.45Å; Y579-W656 VanDerWaalsContact CE1-CB 3.45Å; Y579-W656 AromaticContact CE1-CD2 3.98Å; Y579-W656 HydrophobicContact CE1-CD2 3.98Å; Y579-W656 HydrophobicContact CE1-CE3 4.04Å; Y579-W656 AromaticContact CE1-CG 3.77Å; Y579-W656 HydrophobicContact CE1-CG 3.77Å; Y579-W656 HydrophobicContact CE2-CB 3.44Å; Y579-W656 VanDerWaalsContact CE2-CB 3.44Å; Y579-W656 AromaticContact CE2-CD1 3.81Å; Y579-W656 AromaticContact CE2-CG 3.69Å; Y579-W656 HydrophobicContact CE2-CG 3.69Å; Y579-W656 HydrophobicContact CG-CB 3.96Å; Y579-W656 AromaticContact CG-CD1 3.47Å; Y579-W656 VanDerWaalsContact CG-CD1 3.47Å; Y579-W656 AromaticContact CG-CD2 3.43Å; Y579-W656 HydrophobicContact CG-CD2 3.43Å; Y579-W656 VanDerWaalsContact CG-CD2 3.43Å; Y579-W656 AromaticContact CG-CE2 3.58Å; Y579-W656 HydrophobicContact CG-CE3 4.04Å; Y579-W656 AromaticContact CG-CG 3.39Å; Y579-W656 HydrophobicContact CG-CG 3.39Å; Y579-W656 HydrophobicContact CG-CZ2 4.3Å; Y579-W656 AromaticContact CG-NE1 3.59Å; Y579-W656 AromaticContact CZ-CG 3.83Å; Y579-V663 HydrophobicContact CD1-CB 4.43Å; Y579-V663 HydrophobicContact CD1-CG1 4Å; Y579-V663 HydrophobicContact CD1-CG2 4.24Å; Y579-V663 HydrophobicContact CE1-CB 4.21Å; Y579-V663 HydrophobicContact CE1-CG1 4.2Å; Y579-V663 HydrophobicContact CE1-CG2 4.11Å
580V95.6Very high91.3Very high0 Ų051.4 Ų51.40%026%0.26CS..EExtended strand (participates in β ladder)trans-104.1139.9-169.9-68.40000110.7F571 K572 L574 V582 M626 L634 P635 N636 F666F571-V580 CarbonylContact C-O 3.51Å; F571-V580 VanDerWaalsContact CA-O 3.31Å; F571-V580 WeakPolarHBondContact CA-O 3.29Å; K572-V580 HydrophobicContact CB-CG2 4.31Å; K572-V580 PolarHBondContact N-O 2.77Å; K572-V580 WeakPolarHBondContact O-CG2 3.48Å; K572-V580 PolarHBondContact O-N 3.48Å; L574-V580 HydrophobicContact CB-CG1 4.4Å; L574-V580 HydrophobicContact CB-CG2 4.15Å; L574-V580 HydrophobicContact CD2-CG1 4.2Å; V580-V582 HydrophobicContact CG2-CG1 4.28Å; V580-M626 HydrophobicContact CG1-SD 4.05Å; V580-L634 HydrophobicContact CB-CB 3.97Å; V580-L634 HydrophobicContact CG1-CB 3.91Å; V580-L634 HydrophobicContact CG2-CD1 4.27Å; V580-P635 WeakPolarHBondContact CA-O 3.49Å; V580-N636 HydrophobicContact CG1-CB 4.22Å; V580-F666 HydrophobicContact CG2-CD2 4.33Å
581N96.1Very high91.2Very high2 Ų253.8 Ų53.81%0.01127%0.27CS..EExtended strand (participates in β ladder)trans-85.1125.8167.8-171.5-63.3000109.1D570 F571 N583 F586 P635D570-N581 VanDerWaalsContact CB-ND2 3.32Å; D570-N581 WeakPolarHBondContact CB-ND2 3.25Å; D570-N581 CarbonylContact O-C 3.55Å; D570-N581 WeakPolarHBondContact O-CA 3.49Å; F571-N581 HydrophobicContact CD1-CB 4.39Å; F571-N581 HydrophobicContact CE1-CB 4.02Å; F571-N581 HydrophobicContact CZ-CB 4.33Å; N581-N583 VanDerWaalsContact OD1-CB 3.31Å; N581-N583 WeakPolarHBondContact OD1-CB 3.37Å; N581-N583 PolarHBondContact OD1-N 3.41Å; N581-F586 HydrophobicContact CB-CD1 3.91Å; N581-F586 HydrophobicContact CB-CE1 4.24Å; N581-F586 HydrophobicContact CB-CG 4.23Å; N581-F586 WeakPolarHBondContact OD1-CB 3.19Å; N581-P635 PolarHBondContact N-O 2.97Å; N581-P635 WeakPolarHBondContact O-CD 3.26Å
582V94.4Very high91.2Very high26 Ų2658.5 Ų58.516%0.15830%0.295CS..  trans-102.8-1.4-178.6-600000113.3D570 K572 V580 L634 F666 F675D570-V582 WeakPolarHBondContact O-CG2 3.44Å; D570-V582 PolarHBondContact O-N 3.25Å; K572-V582 HydrophobicContact CB-CG1 4.2Å; K572-V582 HydrophobicContact CG-CG1 3.82Å; K572-V582 HydrophobicContact CG-CG2 3.98Å; V580-V582 HydrophobicContact CG2-CG1 4.28Å; V582-L634 HydrophobicContact CG1-CD2 4.25Å; V582-F666 HydrophobicContact CG1-CD2 3.88Å; V582-F666 HydrophobicContact CG1-CE2 4Å; V582-F675 WeakPolarHBondContact O-CZ 3.23Å
583N92.4Very high90.9Very high51 Ų5158.5 Ų58.527%0.27331%0.305SS..  trans-75.3123.3-178.3-175.4-36.3000110.5D570 N581 D585 F586D570-N583 HydrophobicContact CB-CB 3.95Å; D570-N583 PolarHBondContact OD1-ND2 3.41Å; N581-N583 VanDerWaalsContact OD1-CB 3.31Å; N581-N583 WeakPolarHBondContact OD1-CB 3.37Å; N581-N583 PolarHBondContact OD1-N 3.41Å; N583-D585 PolarHBondContact O-N 3.17Å; N583-D585 WeakPolarHBondContact OD1-CB 3.48Å; N583-D585 PolarHBondContact OD1-N 3.03Å; N583-F586 HydrophobicContact CB-CB 4.43Å; N583-F586 WeakPolarHBondContact O-CB 3.41Å; N583-F586 PolarHBondContact O-N 3.46Å; N583-F586 VanDerWaalsContact O-N 3.11Å
584P88.5Confident90.7Very high66 Ų6659.7 Ų59.743%0.42932%0.323SS..G310 helixtrans-65.9-26.2-174.729.9-38.8000113.1F586 K587 F675P584-F586 VanDerWaalsContact C-N 3.27Å; P584-F586 PolarHBondContact O-N 2.69Å; P584-K587 WeakPolarHBondContact O-CD 3.26Å; P584-K587 VanDerWaalsContact O-CG 3.31Å; P584-K587 WeakPolarHBondContact O-CG 3.38Å; P584-F675 HydrophobicContact CB-CE1 4.06Å; P584-F675 HydrophobicContact CG-CE1 3.71Å; P584-F675 HydrophobicContact CG-CZ 4.41Å
585D91.4Very high90.7Very high100 Ų10067.1 Ų67.154%0.53536%0.356SS..G310 helixtrans-80.7-11.6179.9-67.7-33.5000112.5N583 K587 N588N583-D585 PolarHBondContact O-N 3.17Å; N583-D585 WeakPolarHBondContact OD1-CB 3.48Å; N583-D585 PolarHBondContact OD1-N 3.03Å; D585-K587 PolarHBondContact O-N 3Å; D585-K587 VanDerWaalsContact O-N 3.15Å; D585-N588 WeakPolarHBondContact O-CB 3.27Å; D585-N588 PolarHBondContact O-N 2.9Å; D585-N588 PolarHBondContact O-ND2 3.11Å
586F94.7Very high91Very high5 Ų564 Ų642%0.02234%0.343CS..G310 helixtrans-61.4-24.9178-169.8-109.4000112.3V565 A566 N581 N583 P584 N588 R589 Y590 W622 P635 L637V565-F586 HydrophobicContact CB-CE2 4.24Å; V565-F586 VanDerWaalsContact O-CD2 3.26Å; V565-F586 WeakPolarHBondContact O-CD2 3.38Å; V565-F586 VanDerWaalsContact O-CE2 3.29Å; V565-F586 WeakPolarHBondContact O-CE2 3.34Å; A566-F586 HydrophobicContact CB-CD2 4.13Å; A566-F586 HydrophobicContact CB-CE2 4.01Å; N581-F586 HydrophobicContact CB-CD1 3.91Å; N581-F586 HydrophobicContact CB-CE1 4.24Å; N581-F586 HydrophobicContact CB-CG 4.23Å; N581-F586 WeakPolarHBondContact OD1-CB 3.19Å; N583-F586 HydrophobicContact CB-CB 4.43Å; N583-F586 WeakPolarHBondContact O-CB 3.41Å; N583-F586 PolarHBondContact O-N 3.46Å; N583-F586 VanDerWaalsContact O-N 3.11Å; P584-F586 VanDerWaalsContact C-N 3.27Å; P584-F586 PolarHBondContact O-N 2.69Å; F586-N588 PolarHBondContact O-N 3.33Å; F586-N588 VanDerWaalsContact O-N 3.1Å; F586-R589 HydrophobicContact CD2-CB 4.11Å; F586-R589 HydrophobicContact CD2-CG 4.28Å; F586-R589 HydrophobicContact CE2-CB 4.14Å; F586-R589 WeakPolarHBondContact O-CB 3.47Å; F586-R589 PolarHBondContact O-N 2.97Å; F586-Y590 AromaticContact CD1-CD1 3.63Å; F586-Y590 HydrophobicContact CD1-CD1 3.63Å; F586-Y590 AromaticContact CD1-CE1 3.7Å; F586-Y590 HydrophobicContact CD1-CE1 3.7Å; F586-Y590 AromaticContact CE1-CD1 3.61Å; F586-Y590 HydrophobicContact CE1-CD1 3.61Å; F586-Y590 HydrophobicContact CE1-CE1 4.05Å; F586-Y590 HydrophobicContact CG-CD1 4.46Å; F586-Y590 HydrophobicContact CZ-CD1 4.43Å; F586-Y590 WeakPolarHBondContact O-CD1 3.39Å; F586-Y590 WeakPolarHBondContact O-CE1 3.48Å; F586-W622 HydrophobicContact CE2-CZ3 4.42Å; F586-W622 HydrophobicContact CZ-CE3 4.09Å; F586-W622 AromaticContact CZ-CZ3 3.96Å; F586-W622 HydrophobicContact CZ-CZ3 3.96Å; F586-P635 HydrophobicContact CD1-CB 4.12Å; F586-P635 HydrophobicContact CD1-CG 3.99Å; F586-P635 HydrophobicContact CE1-CB 3.96Å; F586-P635 HydrophobicContact CE1-CG 4.31Å; F586-L637 HydrophobicContact CE1-CD1 3.74Å; F586-L637 HydrophobicContact CE1-CD2 4.28Å; F586-L637 HydrophobicContact CE1-CG 4.5Å; F586-L637 HydrophobicContact CE2-CD1 4.42Å; F586-L637 HydrophobicContact CZ-CD1 3.47Å; F586-L637 VanDerWaalsContact CZ-CD1 3.47Å
587K92.7Very high91.2Very high131 Ų13163.5 Ų63.557%0.5734%0.344SS*.G310 helixtrans-54.7-26.5172.173.4-170.2174.5-1750113.9P584 D585 R589 Y590P584-K587 WeakPolarHBondContact O-CD 3.26Å; P584-K587 VanDerWaalsContact O-CG 3.31Å; P584-K587 WeakPolarHBondContact O-CG 3.38Å; D585-K587 PolarHBondContact O-N 3Å; D585-K587 VanDerWaalsContact O-N 3.15Å; K587-R589 VanDerWaalsContact C-N 3.27Å; K587-R589 PolarHBondContact O-N 3.29Å; K587-Y590 VanDerWaalsContact CA-CE1 3.45Å; K587-Y590 HydrophobicContact CB-CE1 4.36Å
588N94.1Very high90.9Very high94 Ų9463.1 Ų63.150%0.50333%0.333SS..G310 helixtrans-78.7-13.8178-58.4-38.4000112.3D585 F586 N614D585-N588 WeakPolarHBondContact O-CB 3.27Å; D585-N588 PolarHBondContact O-N 2.9Å; D585-N588 PolarHBondContact O-ND2 3.11Å; F586-N588 PolarHBondContact O-N 3.33Å; F586-N588 VanDerWaalsContact O-N 3.1Å; N588-N614 PolarHBondContact O-ND2 3.24Å
589R95.9Very high89.7Confident138 Ų13867.1 Ų67.152%0.52135%0.352SS..THydrogen-bonded Turntrans-97.2-13.1-174-56.1-63.1-172.91741.4113.7F586 K587 N614 W622F586-R589 HydrophobicContact CD2-CB 4.11Å; F586-R589 HydrophobicContact CD2-CG 4.28Å; F586-R589 HydrophobicContact CE2-CB 4.14Å; F586-R589 WeakPolarHBondContact O-CB 3.47Å; F586-R589 PolarHBondContact O-N 2.97Å; K587-R589 VanDerWaalsContact C-N 3.27Å; K587-R589 PolarHBondContact O-N 3.29Å; R589-N614 VanDerWaalsContact C-CB 3.43Å; R589-N614 VanDerWaalsContact O-CB 3.23Å; R589-N614 WeakPolarHBondContact O-CB 3.34Å; R589-N614 PolarHBondContact O-N 3.02Å; R589-W622 VanDerWaalsContact O-CH2 3.26Å; R589-W622 WeakPolarHBondContact O-CH2 3.31Å; R589-W622 VanDerWaalsContact O-CZ3 3.27Å; R589-W622 WeakPolarHBondContact O-CZ3 3.31Å
590Y96.4Very high88.3Confident25 Ų2570.6 Ų70.610%0.09837%0.365CS..EExtended strand (participates in β ladder)trans-127.7156.8178.270-93.6000113.5F586 K587 L592 V611 S612 E625 P635F586-Y590 AromaticContact CD1-CD1 3.63Å; F586-Y590 HydrophobicContact CD1-CD1 3.63Å; F586-Y590 AromaticContact CD1-CE1 3.7Å; F586-Y590 HydrophobicContact CD1-CE1 3.7Å; F586-Y590 AromaticContact CE1-CD1 3.61Å; F586-Y590 HydrophobicContact CE1-CD1 3.61Å; F586-Y590 HydrophobicContact CE1-CE1 4.05Å; F586-Y590 HydrophobicContact CG-CD1 4.46Å; F586-Y590 HydrophobicContact CZ-CD1 4.43Å; F586-Y590 WeakPolarHBondContact O-CD1 3.39Å; F586-Y590 WeakPolarHBondContact O-CE1 3.48Å; K587-Y590 VanDerWaalsContact CA-CE1 3.45Å; K587-Y590 HydrophobicContact CB-CE1 4.36Å; Y590-L592 HydrophobicContact CD2-CD2 4.26Å; Y590-L592 HydrophobicContact CE2-CD2 3.68Å; Y590-L592 HydrophobicContact CE2-CG 4.45Å; Y590-V611 HydrophobicContact CD2-CB 3.62Å; Y590-V611 HydrophobicContact CD2-CG1 3.44Å; Y590-V611 VanDerWaalsContact CD2-CG1 3.44Å; Y590-V611 HydrophobicContact CE2-CB 4.23Å; Y590-V611 HydrophobicContact CE2-CG1 3.52Å; Y590-V611 HydrophobicContact CG-CB 3.99Å; Y590-V611 HydrophobicContact CG-CG1 4.17Å; Y590-S612 CarbonylContact C-O 3.53Å; Y590-S612 WeakPolarHBondContact CA-O 3.48Å; Y590-S612 VanDerWaalsContact CB-O 3.29Å; Y590-S612 WeakPolarHBondContact CB-O 2.82Å; Y590-E625 PolarHBondContact OH-OE1 2.91Å; Y590-P635 HydrophobicContact CD1-CG 4.47Å; Y590-P635 HydrophobicContact CE1-CB 4.31Å; Y590-P635 HydrophobicContact CE1-CG 3.58Å
591K94.9Very high87Confident73 Ų7381.8 Ų81.832%0.31741%0.407SS..EExtended strand (participates in β ladder)trans-105.8149.5170.8-62.3176.4-172.6165.70109.5V611 S612 N614 G616 N619K591-V611 WeakPolarHBondContact O-CA 3.36Å; K591-S612 PolarHBondContact N-O 3.18Å; K591-S612 PolarHBondContact O-N 3.19Å; K591-N614 WeakPolarHBondContact CE-OD1 3.38Å; K591-N614 HydrophobicContact CG-CB 3.95Å; K591-N614 VanDerWaalsContact CG-OD1 3.25Å; K591-N614 WeakPolarHBondContact CG-OD1 3.47Å; K591-G616 PolarHBondContact NZ-O 3.17Å; K591-N619 PolarHBondContact NZ-OD1 2.75Å
592L94.8Very high85.9Confident103 Ų10384.2 Ų84.254%0.53942%0.417SS..EExtended strand (participates in β ladder)trans-85.9134.3173.5-62176.3000110.6Y590 C609 T610 V611 E625Y590-L592 HydrophobicContact CD2-CD2 4.26Å; Y590-L592 HydrophobicContact CE2-CD2 3.68Å; Y590-L592 HydrophobicContact CE2-CG 4.45Å; L592-C609 HydrophobicContact CB-CB 4.33Å; L592-C609 HydrophobicContact CD2-CB 4.06Å; L592-T610 WeakPolarHBondContact CA-O 3.17Å; L592-V611 HydrophobicContact CD2-CG1 4.35Å; L592-E625 HydrophobicContact CD2-CG 4.12Å; L592-E625 VanDerWaalsContact CD2-OE1 3.32Å; L592-E625 WeakPolarHBondContact CD2-OE1 3.28Å
593G90.9Very high84.8Confident38 Ų3891.6 Ų91.639%0.39245%0.45SS..EExtended strand (participates in β ladder)trans-107.1-145.5169.700000112.3T610G593-T610 VanDerWaalsContact CA-OG1 3.29Å; G593-T610 WeakPolarHBondContact CA-OG1 3.08Å; G593-T610 PolarHBondContact N-O 2.81Å
594G88.2Confident84.3Confident50 Ų5091.2 Ų91.252%0.51545%0.448SS..EExtended strand (participates in β ladder)trans-67.5155.2-179.500000113.2V596 C609 T610G594-V596 PolarHBondContact O-N 3.03Å; G594-C609 WeakPolarHBondContact O-CA 3.49Å; G594-T610 PolarHBondContact N-OG1 3.48Å; G594-T610 PolarHBondContact O-N 3.15Å
595K88.6Confident84.2Confident160 Ų16088.6 Ų88.670%0.69643%0.43SS*.EExtended strand (participates in β ladder)trans-62.8130.3173.7-172.2175.4-178.8179.10110
596V83.9Confident84Confident25 Ų2588.3 Ų88.315%0.15243%0.425CS..PPolyproline II helixtrans-82.2125173.8177.40000108.7G594 L598 P607 G608 T610 F624G594-V596 PolarHBondContact O-N 3.03Å; V596-L598 HydrophobicContact CG1-CD2 3.97Å; V596-L598 HydrophobicContact CG1-CG 4.05Å; V596-P607 HydrophobicContact CB-CB 4.03Å; V596-P607 HydrophobicContact CG1-CB 3.96Å; V596-P607 WeakPolarHBondContact O-CG 3.42Å; V596-G608 WeakPolarHBondContact CB-O 3.49Å; V596-G608 PolarHBondContact N-O 3.35Å; V596-T610 HydrophobicContact CG2-CG2 3.49Å; V596-T610 VanDerWaalsContact CG2-CG2 3.49Å; V596-F624 HydrophobicContact CB-CB 4.49Å; V596-F624 HydrophobicContact CG2-CB 3.66Å; V596-F624 HydrophobicContact CG2-CG 4.28Å
597V78.4Confident83.7Confident110 Ų11089.1 Ų89.167%0.66743%0.431SS*.  trans-106.5116.1173.1-177.60000107.5
598L73.4Confident83.6Confident54 Ų5483 Ų8328%0.28341%0.405SS..  trans-104.8130.3168.5-58.4177.5000107.1V596 R600 F602 W605 P607V596-L598 HydrophobicContact CG1-CD2 3.97Å; V596-L598 HydrophobicContact CG1-CG 4.05Å; L598-R600 PolarHBondContact O-N 3.02Å; L598-F602 HydrophobicContact CB-CE2 4.34Å; L598-F602 HydrophobicContact CD1-CE2 3.68Å; L598-F602 HydrophobicContact CD1-CZ 4.29Å; L598-W605 HydrophobicContact CD1-CH2 3.46Å; L598-W605 VanDerWaalsContact CD1-CH2 3.46Å; L598-W605 HydrophobicContact CD1-CZ3 3.81Å; L598-P607 HydrophobicContact CB-CG 4.12Å; L598-P607 HydrophobicContact CD1-CB 3.88Å; L598-P607 HydrophobicContact CD1-CG 3.99Å; L598-P607 HydrophobicContact CG-CB 4.01Å; L598-P607 HydrophobicContact CG-CG 3.87Å
599E63.3Low83.5Confident116 Ų11680.1 Ų80.154%0.54239%0.392SS..SBendtrans-68.1-26.8175.5-66.5-169179.400112T418T418-E599 WeakPolarHBondContact CB-OE2 3.33Å; T418-E599 HydrophobicContact CG2-CG 4.16Å; T418-E599 WeakPolarHBondContact CG2-OE1 3.41Å; T418-E599 WeakPolarHBondContact CG2-OE2 3.24Å; T418-E599 PolarHBondContact OG1-OE2 2.94Å
600R66.3Low83.4Confident116 Ų11675.8 Ų75.844%0.43838%0.381SS..SBendtrans-80.3132.9176.3-177.6167.5171.2175.5-5.9110.5G86 L598 F602G86-R600 PolarHBondContact O-NH1 3.27Å; L598-R600 PolarHBondContact O-N 3.02Å; R600-F602 HydrophobicContact CB-CE2 4.22Å; R600-F602 HydrophobicContact CB-CZ 4.05Å; R600-F602 HydrophobicContact CG-CE1 4.08Å; R600-F602 HydrophobicContact CG-CE2 4.24Å; R600-F602 HydrophobicContact CG-CZ 3.89Å; R600-F602 VanDerWaalsContact O-CE2 3.29Å; R600-F602 WeakPolarHBondContact O-CE2 3.25Å
601R67.1Low83.4Confident235 Ų23574.6 Ų74.689%0.88738%0.376SS*.  trans-87.7141.6168.3-62-175.8-177.5-174.70.7109.8
602F73.9Confident83.4Confident53 Ų5371.9 Ų71.923%0.23237%0.366CS..  trans-117.3145.8174.2-52.3-92.7000107.9L598 R600 W605L598-F602 HydrophobicContact CB-CE2 4.34Å; L598-F602 HydrophobicContact CD1-CE2 3.68Å; L598-F602 HydrophobicContact CD1-CZ 4.29Å; R600-F602 HydrophobicContact CB-CE2 4.22Å; R600-F602 HydrophobicContact CB-CZ 4.05Å; R600-F602 HydrophobicContact CG-CE1 4.08Å; R600-F602 HydrophobicContact CG-CE2 4.24Å; R600-F602 HydrophobicContact CG-CZ 3.89Å; R600-F602 VanDerWaalsContact O-CE2 3.29Å; R600-F602 WeakPolarHBondContact O-CE2 3.25Å; F602-W605 HydrophobicContact CB-CD2 4.03Å; F602-W605 HydrophobicContact CB-CG 4.03Å; F602-W605 HydrophobicContact CB-CZ2 4.31Å; F602-W605 WeakPolarHBondContact CB-O 3.36Å; F602-W605 AromaticContact CD1-CE2 3.69Å; F602-W605 AromaticContact CD1-CZ2 3.6Å; F602-W605 HydrophobicContact CD1-CZ2 3.6Å; F602-W605 AromaticContact CD1-NE1 3.64Å; F602-W605 HydrophobicContact CD2-CD2 4.06Å; F602-W605 AromaticContact CD2-CE2 3.55Å; F602-W605 HydrophobicContact CD2-CE3 4.31Å; F602-W605 AromaticContact CD2-CH2 3.65Å; F602-W605 HydrophobicContact CD2-CH2 3.65Å; F602-W605 AromaticContact CD2-CZ2 3.34Å; F602-W605 HydrophobicContact CD2-CZ2 3.34Å; F602-W605 HydrophobicContact CD2-CZ3 4.11Å; F602-W605 HydrophobicContact CE1-CH2 4.44Å; F602-W605 AromaticContact CE1-CZ2 3.62Å; F602-W605 HydrophobicContact CE1-CZ2 3.62Å; F602-W605 AromaticContact CE2-CH2 3.46Å; F602-W605 HydrophobicContact CE2-CH2 3.46Å; F602-W605 VanDerWaalsContact CE2-CH2 3.46Å; F602-W605 AromaticContact CE2-CZ2 3.39Å; F602-W605 HydrophobicContact CE2-CZ2 3.39Å; F602-W605 HydrophobicContact CE2-CZ3 4.23Å; F602-W605 HydrophobicContact CG-CD2 4.05Å; F602-W605 AromaticContact CG-CE2 3.33Å; F602-W605 HydrophobicContact CG-CH2 4.24Å; F602-W605 AromaticContact CG-CZ2 3.47Å; F602-W605 HydrophobicContact CG-CZ2 3.47Å; F602-W605 VanDerWaalsContact CG-CZ2 3.47Å; F602-W605 AromaticContact CG-NE1 3.48Å; F602-W605 AromaticContact CZ-CH2 3.89Å; F602-W605 HydrophobicContact CZ-CH2 3.89Å; F602-W605 AromaticContact CZ-CZ2 3.53Å; F602-W605 HydrophobicContact CZ-CZ2 3.53Å
603E70.7Confident83.5Confident180 Ų18067 Ų6784%0.84134%0.341SS*.SBendtrans-66.2-52.7-173.8-179.4174.4-169.100111
604D81.4Confident83.6Confident44 Ų4468.4 Ų68.424%0.23534%0.34CS..SBendtrans-94.6-5.1-173.4-78-45.7000113.7Y628 R629D604-Y628 HydrophobicContact CB-CD2 3.99Å; D604-Y628 HydrophobicContact CB-CE2 3.29Å; D604-Y628 CarbonylContact O-C 3.53Å; D604-Y628 WeakPolarHBondContact O-CA 3.16Å; D604-Y628 WeakPolarHBondContact O-CD2 3.42Å; D604-Y628 PolarHBondContact OD2-OH 2.99Å; D604-R629 HydrophobicContact CB-CG 4.37Å; D604-R629 PolarHBondContact O-N 3.44Å; D604-R629 IonicContact OD1-NE 3.25Å; D604-R629 PolarHBondContact OD1-NE 2.85Å; D604-R629 IonicContact OD1-NH2 2.66Å; D604-R629 IonicContact OD2-NH2 3.83Å
605W86.4Confident83.9Confident10 Ų1070 Ų704%0.03834%0.336CS..EExtended strand (participates in β ladder)trans-150.7156.3-177.869.8-88.5000116.2H578 L598 F602 P607 F624 M626 K627 Y628H578-W605 AromaticContact CE1-CZ2 3.73Å; H578-W605 AromaticContact NE2-CZ2 3.76Å; L598-W605 HydrophobicContact CD1-CH2 3.46Å; L598-W605 VanDerWaalsContact CD1-CH2 3.46Å; L598-W605 HydrophobicContact CD1-CZ3 3.81Å; F602-W605 HydrophobicContact CB-CD2 4.03Å; F602-W605 HydrophobicContact CB-CG 4.03Å; F602-W605 HydrophobicContact CB-CZ2 4.31Å; F602-W605 WeakPolarHBondContact CB-O 3.36Å; F602-W605 AromaticContact CD1-CE2 3.69Å; F602-W605 AromaticContact CD1-CZ2 3.6Å; F602-W605 HydrophobicContact CD1-CZ2 3.6Å; F602-W605 AromaticContact CD1-NE1 3.64Å; F602-W605 HydrophobicContact CD2-CD2 4.06Å; F602-W605 AromaticContact CD2-CE2 3.55Å; F602-W605 HydrophobicContact CD2-CE3 4.31Å; F602-W605 AromaticContact CD2-CH2 3.65Å; F602-W605 HydrophobicContact CD2-CH2 3.65Å; F602-W605 AromaticContact CD2-CZ2 3.34Å; F602-W605 HydrophobicContact CD2-CZ2 3.34Å; F602-W605 HydrophobicContact CD2-CZ3 4.11Å; F602-W605 HydrophobicContact CE1-CH2 4.44Å; F602-W605 AromaticContact CE1-CZ2 3.62Å; F602-W605 HydrophobicContact CE1-CZ2 3.62Å; F602-W605 AromaticContact CE2-CH2 3.46Å; F602-W605 HydrophobicContact CE2-CH2 3.46Å; F602-W605 VanDerWaalsContact CE2-CH2 3.46Å; F602-W605 AromaticContact CE2-CZ2 3.39Å; F602-W605 HydrophobicContact CE2-CZ2 3.39Å; F602-W605 HydrophobicContact CE2-CZ3 4.23Å; F602-W605 HydrophobicContact CG-CD2 4.05Å; F602-W605 AromaticContact CG-CE2 3.33Å; F602-W605 HydrophobicContact CG-CH2 4.24Å; F602-W605 AromaticContact CG-CZ2 3.47Å; F602-W605 HydrophobicContact CG-CZ2 3.47Å; F602-W605 VanDerWaalsContact CG-CZ2 3.47Å; F602-W605 AromaticContact CG-NE1 3.48Å; F602-W605 AromaticContact CZ-CH2 3.89Å; F602-W605 HydrophobicContact CZ-CH2 3.89Å; F602-W605 AromaticContact CZ-CZ2 3.53Å; F602-W605 HydrophobicContact CZ-CZ2 3.53Å; W605-P607 HydrophobicContact CZ3-CB 4.18Å; W605-F624 HydrophobicContact CH2-CE2 4.08Å; W605-F624 HydrophobicContact CH2-CZ 4.3Å; W605-F624 AromaticContact CZ3-CE2 3.86Å; W605-F624 HydrophobicContact CZ3-CE2 3.86Å; W605-M626 HydrophobicContact CB-CE 4.48Å; W605-M626 HydrophobicContact CD2-CE 3.26Å; W605-M626 HydrophobicContact CD2-CG 4.45Å; W605-M626 HydrophobicContact CE3-CB 4.12Å; W605-M626 HydrophobicContact CE3-CE 3.68Å; W605-M626 HydrophobicContact CE3-CG 3.9Å; W605-M626 HydrophobicContact CG-CE 3.63Å; W605-M626 HydrophobicContact CH2-CE 4.07Å; W605-M626 HydrophobicContact CZ2-CE 3.68Å; W605-M626 HydrophobicContact CZ3-CE 4.08Å; W605-M626 HydrophobicContact CZ3-CG 4Å; W605-K627 VanDerWaalsContact CA-O 3.22Å; W605-K627 WeakPolarHBondContact CA-O 3.28Å; W605-K627 WeakPolarHBondContact CB-O 3.38Å; W605-Y628 HydrophobicContact CB-CD2 3.99Å
606E87.3Confident83.8Confident94 Ų9464.7 Ų64.744%0.43933%0.327SS..EExtended strand (participates in β ladder)trans-124.5147170.964.5171.8-152.400111.6K627E606-K627 HydrophobicContact CG-CB 3.73Å; E606-K627 HydrophobicContact CG-CD 3.85Å; E606-K627 HydrophobicContact CG-CG 4.36Å; E606-K627 PolarHBondContact N-O 3.49Å; E606-K627 PolarHBondContact O-N 3.08Å; E606-K627 WeakPolarHBondContact OE1-CD 3.38Å; E606-K627 IonicContact OE1-NZ 3.86Å; E606-K627 PolarHBondContact OE1-NZ 2.98Å; E606-K627 VanDerWaalsContact OE1-NZ 3.11Å
607P89Confident84.1Confident22 Ų2267.6 Ų67.614%0.14334%0.342CS..EExtended strand (participates in β ladder)trans-67.7135174.928.5-35.1000111.2V596 L598 W605 F624V596-P607 HydrophobicContact CB-CB 4.03Å; V596-P607 HydrophobicContact CG1-CB 3.96Å; V596-P607 WeakPolarHBondContact O-CG 3.42Å; L598-P607 HydrophobicContact CB-CG 4.12Å; L598-P607 HydrophobicContact CD1-CB 3.88Å; L598-P607 HydrophobicContact CD1-CG 3.99Å; L598-P607 HydrophobicContact CG-CB 4.01Å; L598-P607 HydrophobicContact CG-CG 3.87Å; W605-P607 HydrophobicContact CZ3-CB 4.18Å; P607-F624 HydrophobicContact CB-CD2 4.49Å
608G90.4Very high84.6Confident3 Ų362.6 Ų62.63%0.03131%0.311CS..EExtended strand (participates in β ladder)trans-93.2-134.217000000111.9V596 E625V596-G608 WeakPolarHBondContact CB-O 3.49Å; V596-G608 PolarHBondContact N-O 3.35Å; G608-E625 PolarHBondContact N-O 2.7Å
609C92.8Very high85.4Confident33 Ų3362.5 Ų62.522%0.22331%0.311CS..EExtended strand (participates in β ladder)trans-97.5162.2179.9-670000112.3L592 G594 F624 E625L592-C609 HydrophobicContact CB-CB 4.33Å; L592-C609 HydrophobicContact CD2-CB 4.06Å; G594-C609 WeakPolarHBondContact O-CA 3.49Å; C609-F624 CarbonylContact O-C 3.6Å; C609-F624 VanDerWaalsContact O-CA 3.25Å; C609-F624 WeakPolarHBondContact O-CA 3.42Å; C609-F624 WeakPolarHBondContact O-CB 3.44Å; C609-E625 PolarHBondContact N-OE2 2.94Å; C609-E625 PolarHBondContact O-N 2.92Å
610T93.4Very high86.8Confident48 Ų4859.7 Ų59.729%0.29430%0.297SS..EExtended strand (participates in β ladder)trans-64.4146169570000110.2L592 G593 G594 V596L592-T610 WeakPolarHBondContact CA-O 3.17Å; G593-T610 VanDerWaalsContact CA-OG1 3.29Å; G593-T610 WeakPolarHBondContact CA-OG1 3.08Å; G593-T610 PolarHBondContact N-O 2.81Å; G594-T610 PolarHBondContact N-OG1 3.48Å; G594-T610 PolarHBondContact O-N 3.15Å; V596-T610 HydrophobicContact CG2-CG2 3.49Å; V596-T610 VanDerWaalsContact CG2-CG2 3.49Å
611V95.7Very high88Confident0 Ų059.2 Ų59.20%030%0.303CS..EExtended strand (participates in β ladder)trans-116.6131.8176.9-57.10000110.8Y590 K591 L592 W622 G623 E625 L637Y590-V611 HydrophobicContact CD2-CB 3.62Å; Y590-V611 HydrophobicContact CD2-CG1 3.44Å; Y590-V611 VanDerWaalsContact CD2-CG1 3.44Å; Y590-V611 HydrophobicContact CE2-CB 4.23Å; Y590-V611 HydrophobicContact CE2-CG1 3.52Å; Y590-V611 HydrophobicContact CG-CB 3.99Å; Y590-V611 HydrophobicContact CG-CG1 4.17Å; K591-V611 WeakPolarHBondContact O-CA 3.36Å; L592-V611 HydrophobicContact CD2-CG1 4.35Å; V611-W622 HydrophobicContact CG2-CB 4.26Å; V611-W622 PolarHBondContact O-N 3.25Å; V611-G623 VanDerWaalsContact CG2-C 3.5Å; V611-G623 PolarHBondContact N-O 2.87Å; V611-G623 PolarHBondContact O-N 3.45Å; V611-E625 HydrophobicContact CG1-CG 3.68Å; V611-L637 HydrophobicContact CG2-CD2 3.71Å
612S95.4Very high89.4Confident15 Ų1548 Ų4811%0.10526%0.261CS..EExtended strand (participates in β ladder)trans-134.4159.7-179.467.10000112.1Y590 K591 N614 K620Y590-S612 CarbonylContact C-O 3.53Å; Y590-S612 WeakPolarHBondContact CA-O 3.48Å; Y590-S612 VanDerWaalsContact CB-O 3.29Å; Y590-S612 WeakPolarHBondContact CB-O 2.82Å; K591-S612 PolarHBondContact N-O 3.18Å; K591-S612 PolarHBondContact O-N 3.19Å; S612-N614 PolarHBondContact O-N 2.77Å; S612-K620 CarbonylContact C-O 3.56Å; S612-K620 VanDerWaalsContact CA-O 3.27Å; S612-K620 WeakPolarHBondContact CA-O 3.3Å
613C96Very high90.3Very high0 Ų046.6 Ų46.60%026%0.261CS..EExtended strand (participates in β ladder)trans-56.1127.6-176.8-175.60000113.4N615 C618 N619 K620 W622C613-N615 VanDerWaalsContact C-N 3.35Å; C613-N615 VanDerWaalsContact SG-CB 3.54Å; C613-N615 PolarHBondContact SG-N 2.98Å; C613-N615 VanDerWaalsContact SG-N 3.36Å; C613-C618 HydrophobicContact CB-CB 4.19Å; C613-C618 VanDerWaalsContact SG-SG 3.64Å; C613-N619 PolarHBondContact O-N 2.91Å; C613-K620 HydrophobicContact CB-CB 4.09Å; C613-K620 PolarHBondContact N-O 2.93Å; C613-W622 VanDerWaalsContact CA-CZ2 3.45Å; C613-W622 HydrophobicContact CB-CH2 3.95Å; C613-W622 HydrophobicContact CB-CZ2 3.31Å; C613-W622 WeakPolarHBondContact SG-CZ2 3.28Å
614N94.7Very high91.4Very high69 Ų6940 Ų4037%0.36923%0.23SC..  trans-89.410175-164.224.8000114.4N588 R589 K591 S612 G616N588-N614 PolarHBondContact O-ND2 3.24Å; R589-N614 VanDerWaalsContact C-CB 3.43Å; R589-N614 VanDerWaalsContact O-CB 3.23Å; R589-N614 WeakPolarHBondContact O-CB 3.34Å; R589-N614 PolarHBondContact O-N 3.02Å; K591-N614 WeakPolarHBondContact CE-OD1 3.38Å; K591-N614 HydrophobicContact CG-CB 3.95Å; K591-N614 VanDerWaalsContact CG-OD1 3.25Å; K591-N614 WeakPolarHBondContact CG-OD1 3.47Å; S612-N614 PolarHBondContact O-N 2.77Å; N614-G616 PolarHBondContact O-N 3.03Å
615N92.8Very high92Very high82 Ų8238.7 Ų38.744%0.43922%0.222SC..SBendtrans-85.493.7-179.5-169.552.9000111.6C561 A563 C613 N617 C618C561-N615 PolarHBondContact SG-ND2 2.88Å; C561-N615 VanDerWaalsContact SG-ND2 3.42Å; A563-N615 HydrophobicContact CB-CB 4.02Å; C613-N615 VanDerWaalsContact C-N 3.35Å; C613-N615 VanDerWaalsContact SG-CB 3.54Å; C613-N615 PolarHBondContact SG-N 2.98Å; C613-N615 VanDerWaalsContact SG-N 3.36Å; N615-N617 PolarHBondContact O-N 3.15Å; N615-C618 WeakPolarHBondContact O-CB 3.39Å; N615-C618 PolarHBondContact O-N 2.89Å; N615-C618 VanDerWaalsContact O-N 3.11Å
616G88.4Confident92.3Very high49 Ų4938.2 Ų38.251%0.50522%0.22SC..THydrogen-bonded Turntrans57.4-126.6179.100000112.6K591 N614 C618K591-G616 PolarHBondContact NZ-O 3.17Å; N614-G616 PolarHBondContact O-N 3.03Å; G616-C618 VanDerWaalsContact C-N 3.32Å
617N88.8Confident92.5Very high87 Ų8737 Ų3747%0.46521%0.214SC..THydrogen-bonded Turntrans-864.3-179.8-69.3-11.1000114.2T321 A322 N615 N619T321-N617 WeakPolarHBondContact CA-O 3.16Å; T321-N617 WeakPolarHBondContact CB-O 3.46Å; A322-N617 PolarHBondContact O-ND2 3.12Å; N615-N617 PolarHBondContact O-N 3.15Å; N617-N619 PolarHBondContact O-N 3.37Å; N617-N619 PolarHBondContact O-ND2 3.31Å
618C90.1Very high92.5Very high4 Ų436.7 Ų36.73%0.02721%0.21CC..  trans-60.7-49.6-171.4178.80000113.7I323 C558 N560 C561 C613 N615 G616 K620I323-C618 HydrophobicContact CD1-CB 3.76Å; C558-C618 VanDerWaalsContact SG-SG 3.7Å; N560-C618 PolarHBondContact ND2-SG 3.4Å; C561-C618 HydrophobicContact CB-CB 3.91Å; C561-C618 VanDerWaalsContact CB-SG 3.6Å; C613-C618 HydrophobicContact CB-CB 4.19Å; C613-C618 VanDerWaalsContact SG-SG 3.64Å; N615-C618 WeakPolarHBondContact O-CB 3.39Å; N615-C618 PolarHBondContact O-N 2.89Å; N615-C618 VanDerWaalsContact O-N 3.11Å; G616-C618 VanDerWaalsContact C-N 3.32Å; C618-K620 PolarHBondContact O-N 3.19Å
619N90.1Very high92.3Very high52 Ų5241.6 Ų41.628%0.27823%0.227SC..  trans4725.5175.3-57.5-42.6000115.1T321 K591 C613 N617 D621T321-N619 HydrophobicContact CG2-CB 4.23Å; K591-N619 PolarHBondContact NZ-OD1 2.75Å; C613-N619 PolarHBondContact O-N 2.91Å; N617-N619 PolarHBondContact O-N 3.37Å; N617-N619 PolarHBondContact O-ND2 3.31Å; N619-D621 PolarHBondContact O-N 3.4Å
620K91.6Very high91.8Very high58 Ų5849 Ų4925%0.25226%0.256SS..  trans-66.8124-179179.364174.7-176.50110N560 S612 C613 C618 W622N560-K620 HydrophobicContact CB-CB 3.79Å; N560-K620 HydrophobicContact CB-CD 3.99Å; N560-K620 HydrophobicContact CB-CG 3.84Å; S612-K620 CarbonylContact C-O 3.56Å; S612-K620 VanDerWaalsContact CA-O 3.27Å; S612-K620 WeakPolarHBondContact CA-O 3.3Å; C613-K620 HydrophobicContact CB-CB 4.09Å; C613-K620 PolarHBondContact N-O 2.93Å; C618-K620 PolarHBondContact O-N 3.19Å; K620-W622 VanDerWaalsContact O-CD1 3.26Å; K620-W622 PolarHBondContact O-N 2.87Å
621D92.4Very high91.2Very high105 Ų10550.6 Ų50.656%0.56127%0.265SS*.EExtended strand (participates in β ladder)trans-60.7131.9174-66-29.3000111.8N619 N641N619-D621 PolarHBondContact O-N 3.4Å; D621-N641 PolarHBondContact O-ND2 3.03Å; D621-N641 VanDerWaalsContact O-ND2 3.09Å
622W95.3Very high90.7Very high1 Ų150.6 Ų50.60%0.00427%0.265CS..EExtended strand (participates in β ladder)trans-115.6-37-177.8-73.4-10.5000112.9C558 V565 F586 R589 V611 C613 K620 L637 A638 N641 F642C558-W622 HydrophobicContact CB-CZ2 3.75Å; C558-W622 PolarHBondContact SG-NE1 3.12Å; V565-W622 HydrophobicContact CB-CH2 3.87Å; V565-W622 HydrophobicContact CB-CZ2 4.42Å; V565-W622 HydrophobicContact CB-CZ3 4.37Å; V565-W622 HydrophobicContact CG1-CH2 3.28Å; V565-W622 HydrophobicContact CG1-CZ2 3.63Å; V565-W622 HydrophobicContact CG1-CZ3 4.22Å; V565-W622 HydrophobicContact CG2-CH2 4.38Å; F586-W622 HydrophobicContact CE2-CZ3 4.42Å; F586-W622 HydrophobicContact CZ-CE3 4.09Å; F586-W622 AromaticContact CZ-CZ3 3.96Å; F586-W622 HydrophobicContact CZ-CZ3 3.96Å; R589-W622 VanDerWaalsContact O-CH2 3.26Å; R589-W622 WeakPolarHBondContact O-CH2 3.31Å; R589-W622 VanDerWaalsContact O-CZ3 3.27Å; R589-W622 WeakPolarHBondContact O-CZ3 3.31Å; V611-W622 HydrophobicContact CG2-CB 4.26Å; V611-W622 PolarHBondContact O-N 3.25Å; C613-W622 VanDerWaalsContact CA-CZ2 3.45Å; C613-W622 HydrophobicContact CB-CH2 3.95Å; C613-W622 HydrophobicContact CB-CZ2 3.31Å; C613-W622 WeakPolarHBondContact SG-CZ2 3.28Å; K620-W622 VanDerWaalsContact O-CD1 3.26Å; K620-W622 PolarHBondContact O-N 2.87Å; W622-L637 HydrophobicContact CB-CD2 4.23Å; W622-A638 PolarHBondContact O-N 3.35Å; W622-N641 PolarHBondContact O-ND2 3.42Å; W622-N641 VanDerWaalsContact O-ND2 3.15Å; W622-F642 HydrophobicContact CB-CE1 4.46Å; W622-F642 HydrophobicContact CB-CE2 4.19Å; W622-F642 HydrophobicContact CB-CZ 3.61Å; W622-F642 AromaticContact CD1-CE1 3.86Å; W622-F642 AromaticContact CD1-CZ 3.72Å; W622-F642 AromaticContact CD2-CE1 3.59Å; W622-F642 HydrophobicContact CD2-CE1 3.59Å; W622-F642 AromaticContact CD2-CZ 3.61Å; W622-F642 HydrophobicContact CD2-CZ 3.61Å; W622-F642 AromaticContact CE2-CE1 3.67Å; W622-F642 HydrophobicContact CE3-CE1 4.11Å; W622-F642 HydrophobicContact CE3-CZ 4.13Å; W622-F642 AromaticContact CG-CE1 3.75Å; W622-F642 HydrophobicContact CG-CE1 3.75Å; W622-F642 HydrophobicContact CG-CE2 4.2Å; W622-F642 AromaticContact CG-CZ 3.35Å; W622-F642 HydrophobicContact CG-CZ 3.35Å; W622-F642 HydrophobicContact CZ2-CE1 4.28Å; W622-F642 AromaticContact NE1-CE1 3.8Å
623G94Very high90.5Very high22 Ų2254.3 Ų54.323%0.22728%0.283CS..EExtended strand (participates in β ladder)trans169.6-140.8-175.600000112.2V611 N636V611-G623 VanDerWaalsContact CG2-C 3.5Å; V611-G623 PolarHBondContact N-O 2.87Å; V611-G623 PolarHBondContact O-N 3.45Å; G623-N636 WeakPolarHBondContact CA-O 3.47Å
624F94Very high90.4Very high42 Ų4254.3 Ų54.318%0.18428%0.283CS..EExtended strand (participates in β ladder)trans-150.9160.217662.9-84.2000111.6V596 W605 P607 C609 M626 N636V596-F624 HydrophobicContact CB-CB 4.49Å; V596-F624 HydrophobicContact CG2-CB 3.66Å; V596-F624 HydrophobicContact CG2-CG 4.28Å; W605-F624 HydrophobicContact CH2-CE2 4.08Å; W605-F624 HydrophobicContact CH2-CZ 4.3Å; W605-F624 AromaticContact CZ3-CE2 3.86Å; W605-F624 HydrophobicContact CZ3-CE2 3.86Å; P607-F624 HydrophobicContact CB-CD2 4.49Å; C609-F624 CarbonylContact O-C 3.6Å; C609-F624 VanDerWaalsContact O-CA 3.25Å; C609-F624 WeakPolarHBondContact O-CA 3.42Å; C609-F624 WeakPolarHBondContact O-CB 3.44Å; F624-M626 HydrophobicContact CD2-CG 4.36Å; F624-M626 HydrophobicContact CE2-CG 3.79Å; F624-N636 WeakPolarHBondContact CZ-ND2 3.44Å; F624-N636 PolarHBondContact N-O 3.32Å; F624-N636 PolarHBondContact O-N 3.22Å
625E94.5Very high90.4Very high17 Ų1751.4 Ų51.48%0.07927%0.267CS..EExtended strand (participates in β ladder)trans-74.6140.4174-63.8178.2132.500111.7Y590 L592 G608 C609 V611 I633Y590-E625 PolarHBondContact OH-OE1 2.91Å; L592-E625 HydrophobicContact CD2-CG 4.12Å; L592-E625 VanDerWaalsContact CD2-OE1 3.32Å; L592-E625 WeakPolarHBondContact CD2-OE1 3.28Å; G608-E625 PolarHBondContact N-O 2.7Å; C609-E625 PolarHBondContact N-OE2 2.94Å; C609-E625 PolarHBondContact O-N 2.92Å; V611-E625 HydrophobicContact CG1-CG 3.68Å; E625-I633 HydrophobicContact CB-CG2 4.17Å; E625-I633 HydrophobicContact CG-CG2 4.15Å; E625-I633 WeakPolarHBondContact OE1-CG2 3.28Å
626M92.1Very high90.5Very high0 Ų048.4 Ų48.40%025%0.252CS..EExtended strand (participates in β ladder)trans-110.6124.3167.1-65.4175.371.700108.4L574 H578 V580 W605 F624 Y628 L634 N636L574-M626 HydrophobicContact CD2-CE 3.8Å; L574-M626 HydrophobicContact CD2-SD 4.43Å; H578-M626 HydrophobicContact CB-CE 3.91Å; H578-M626 HydrophobicContact CB-SD 3.75Å; V580-M626 HydrophobicContact CG1-SD 4.05Å; W605-M626 HydrophobicContact CB-CE 4.48Å; W605-M626 HydrophobicContact CD2-CE 3.26Å; W605-M626 HydrophobicContact CD2-CG 4.45Å; W605-M626 HydrophobicContact CE3-CB 4.12Å; W605-M626 HydrophobicContact CE3-CE 3.68Å; W605-M626 HydrophobicContact CE3-CG 3.9Å; W605-M626 HydrophobicContact CG-CE 3.63Å; W605-M626 HydrophobicContact CH2-CE 4.07Å; W605-M626 HydrophobicContact CZ2-CE 3.68Å; W605-M626 HydrophobicContact CZ3-CE 4.08Å; W605-M626 HydrophobicContact CZ3-CG 4Å; F624-M626 HydrophobicContact CD2-CG 4.36Å; F624-M626 HydrophobicContact CE2-CG 3.79Å; M626-Y628 PolarHBondContact O-N 3.33Å; M626-L634 PolarHBondContact N-O 3.4Å; M626-L634 PolarHBondContact O-N 3.04Å; M626-N636 HydrophobicContact CG-CB 3.76Å; M626-N636 HydrophobicContact SD-CB 3.39Å; M626-N636 WeakPolarHBondContact SD-CB 3.31Å
627K90.9Very high90.9Very high69 Ų6946.2 Ų46.230%0.323%0.228SC..EExtended strand (participates in β ladder)trans-93.195.9172.5-61.7175.1-178178.90108.6W605 E606 A632 I633W605-K627 VanDerWaalsContact CA-O 3.22Å; W605-K627 WeakPolarHBondContact CA-O 3.28Å; W605-K627 WeakPolarHBondContact CB-O 3.38Å; E606-K627 HydrophobicContact CG-CB 3.73Å; E606-K627 HydrophobicContact CG-CD 3.85Å; E606-K627 HydrophobicContact CG-CG 4.36Å; E606-K627 PolarHBondContact N-O 3.49Å; E606-K627 PolarHBondContact O-N 3.08Å; E606-K627 WeakPolarHBondContact OE1-CD 3.38Å; E606-K627 IonicContact OE1-NZ 3.86Å; E606-K627 PolarHBondContact OE1-NZ 2.98Å; E606-K627 VanDerWaalsContact OE1-NZ 3.11Å; K627-A632 CarbonylContact C-O 3.15Å; K627-A632 WeakPolarHBondContact CA-O 3.43Å; K627-I633 HydrophobicContact CG-CG1 4.44Å
628Y89.9Confident91.1Very high15 Ų1543.8 Ų43.86%0.05922%0.22CC..EExtended strand (participates in β ladder)trans-88130.1-177-170.2-97.1000110.9L574 D604 W605 M626 K630 V631 A632 F666 F668L574-Y628 HydrophobicContact CD1-CD2 3.94Å; L574-Y628 HydrophobicContact CD1-CE2 3.62Å; L574-Y628 HydrophobicContact CD2-CD2 3.77Å; L574-Y628 HydrophobicContact CD2-CE2 4.22Å; L574-Y628 HydrophobicContact CD2-CG 4.42Å; L574-Y628 HydrophobicContact CG-CD2 4.4Å; L574-Y628 HydrophobicContact CG-CE2 4.37Å; D604-Y628 HydrophobicContact CB-CD2 3.99Å; D604-Y628 HydrophobicContact CB-CE2 3.29Å; D604-Y628 CarbonylContact O-C 3.53Å; D604-Y628 WeakPolarHBondContact O-CA 3.16Å; D604-Y628 WeakPolarHBondContact O-CD2 3.42Å; D604-Y628 PolarHBondContact OD2-OH 2.99Å; W605-Y628 HydrophobicContact CB-CD2 3.99Å; M626-Y628 PolarHBondContact O-N 3.33Å; Y628-K630 PolarHBondContact O-N 3.23Å; Y628-V631 PolarHBondContact O-N 3.48Å; Y628-A632 PolarHBondContact N-O 3.49Å; Y628-A632 PolarHBondContact O-N 3.38Å; Y628-F666 HydrophobicContact CD1-CE1 4.05Å; Y628-F666 AromaticContact CE1-CE1 3.97Å; Y628-F666 HydrophobicContact CE1-CE1 3.97Å; Y628-F668 AromaticContact CD1-CD2 3.75Å; Y628-F668 HydrophobicContact CD1-CD2 3.75Å; Y628-F668 HydrophobicContact CD1-CE2 4.15Å; Y628-F668 HydrophobicContact CE1-CB 4.21Å; Y628-F668 AromaticContact CE1-CD2 3.74Å; Y628-F668 HydrophobicContact CE1-CD2 3.74Å; Y628-F668 HydrophobicContact CE1-CE2 4.45Å; Y628-F668 HydrophobicContact CE1-CG 4.17Å
629R86Confident91.4Very high105 Ų10543.8 Ų43.840%0.39622%0.22SC..THydrogen-bonded Turntrans46.628.3-175.1-67.6-177.1173.6178.12.6114.4D604 V631 F668D604-R629 HydrophobicContact CB-CG 4.37Å; D604-R629 PolarHBondContact O-N 3.44Å; D604-R629 IonicContact OD1-NE 3.25Å; D604-R629 PolarHBondContact OD1-NE 2.85Å; D604-R629 IonicContact OD1-NH2 2.66Å; D604-R629 IonicContact OD2-NH2 3.83Å; R629-V631 PolarHBondContact O-N 3.29Å; R629-V631 VanDerWaalsContact O-N 3.08Å; R629-F668 HydrophobicContact CB-CE2 4.16Å; R629-F668 HydrophobicContact CB-CZ 4.13Å
630K80.9Confident91.6Very high190 Ų19047.1 Ų47.183%0.82623%0.232SC*.THydrogen-bonded Turntrans60.46.3-174.9-53.2175.7179.9173.20115.3Y628Y628-K630 PolarHBondContact O-N 3.23Å
631V80.9Confident91.8Very high80 Ų8045.6 Ų45.649%0.48523%0.226SC..THydrogen-bonded Turntrans-113.8-47-175.5176.90000111Y628 R629 F668 F676Y628-V631 PolarHBondContact O-N 3.48Å; R629-V631 PolarHBondContact O-N 3.29Å; R629-V631 VanDerWaalsContact O-N 3.08Å; V631-F668 HydrophobicContact CB-CZ 4.45Å; V631-F676 HydrophobicContact CG1-CE2 4.19Å; V631-F676 HydrophobicContact CG1-CZ 4.32Å
632A85.4Confident92Very high0 Ų040.6 Ų40.60%020%0.2CC..EExtended strand (participates in β ladder)trans-95.5125.2-174.700000111.1K627 Y628 L634 Y671K627-A632 CarbonylContact C-O 3.15Å; K627-A632 WeakPolarHBondContact CA-O 3.43Å; Y628-A632 PolarHBondContact N-O 3.49Å; Y628-A632 PolarHBondContact O-N 3.38Å; A632-L634 HydrophobicContact CB-CD1 4.17Å; A632-L634 HydrophobicContact CB-CD2 4.32Å; A632-L634 HydrophobicContact CB-CG 3.98Å; A632-Y671 HydrophobicContact CB-CD1 4.08Å; A632-Y671 HydrophobicContact CB-CE1 3.41Å; A632-Y671 VanDerWaalsContact CB-CE1 3.41Å
633I90.9Very high92.1Very high93 Ų9340.6 Ų40.648%0.47720%0.2SC..EExtended strand (participates in β ladder)trans-99.3107.5171.3-56.2-179.9000107.9E625 K627E625-I633 HydrophobicContact CB-CG2 4.17Å; E625-I633 HydrophobicContact CG-CG2 4.15Å; E625-I633 WeakPolarHBondContact OE1-CG2 3.28Å; K627-I633 HydrophobicContact CG-CG1 4.44Å
634L94.1Very high92.2Very high1 Ų139.6 Ų39.61%0.00519%0.189CC..EExtended strand (participates in β ladder)trans-119.4110.4-169.2-63.6179.8000110.5V580 V582 M626 A632 N636 F666 Y671V580-L634 HydrophobicContact CB-CB 3.97Å; V580-L634 HydrophobicContact CG1-CB 3.91Å; V580-L634 HydrophobicContact CG2-CD1 4.27Å; V582-L634 HydrophobicContact CG1-CD2 4.25Å; M626-L634 PolarHBondContact N-O 3.4Å; M626-L634 PolarHBondContact O-N 3.04Å; A632-L634 HydrophobicContact CB-CD1 4.17Å; A632-L634 HydrophobicContact CB-CD2 4.32Å; A632-L634 HydrophobicContact CB-CG 3.98Å; L634-N636 PolarHBondContact O-N 2.73Å; L634-F666 HydrophobicContact CD1-CD2 4.4Å; L634-F666 HydrophobicContact CD1-CE1 4.45Å; L634-F666 HydrophobicContact CD1-CE2 3.76Å; L634-F666 HydrophobicContact CD1-CZ 3.79Å; L634-Y671 HydrophobicContact CD2-CE2 3.91Å
635P95.8Very high92.3Very high7 Ų739.4 Ų39.45%0.04519%0.189CC..EExtended strand (participates in β ladder)trans-67114.4176.7-25.438.4000111.5V580 N581 F586 Y590 L637V580-P635 WeakPolarHBondContact CA-O 3.49Å; N581-P635 PolarHBondContact N-O 2.97Å; N581-P635 WeakPolarHBondContact O-CD 3.26Å; F586-P635 HydrophobicContact CD1-CB 4.12Å; F586-P635 HydrophobicContact CD1-CG 3.99Å; F586-P635 HydrophobicContact CE1-CB 3.96Å; F586-P635 HydrophobicContact CE1-CG 4.31Å; Y590-P635 HydrophobicContact CD1-CG 4.47Å; Y590-P635 HydrophobicContact CE1-CB 4.31Å; Y590-P635 HydrophobicContact CE1-CG 3.58Å; P635-L637 HydrophobicContact CB-CD2 4.04Å
636N95.1Very high92.4Very high20 Ų2039.1 Ų39.111%0.10719%0.188CC..EExtended strand (participates in β ladder)trans-92.4115.7175.7173.640.1000110.4Y579 V580 G623 F624 M626 L634Y579-N636 PolarHBondContact N-OD1 3.12Å; Y579-N636 VanDerWaalsContact N-OD1 3.15Å; Y579-N636 WeakPolarHBondContact O-CA 3.35Å; Y579-N636 PolarHBondContact O-OD1 3.31Å; V580-N636 HydrophobicContact CG1-CB 4.22Å; G623-N636 WeakPolarHBondContact CA-O 3.47Å; F624-N636 WeakPolarHBondContact CZ-ND2 3.44Å; F624-N636 PolarHBondContact N-O 3.32Å; F624-N636 PolarHBondContact O-N 3.22Å; M626-N636 HydrophobicContact CG-CB 3.76Å; M626-N636 HydrophobicContact SD-CB 3.39Å; M626-N636 WeakPolarHBondContact SD-CB 3.31Å; L634-N636 PolarHBondContact O-N 2.73Å
637L95.3Very high92.5Very high3 Ų343.2 Ų43.22%0.01622%0.215CC..EExtended strand (participates in β ladder)trans-111.3140.1-166.5-53.8-171.2000112.2F571 Y579 F586 V611 W622 P635 F642 W656F571-L637 HydrophobicContact CE1-CB 4.15Å; F571-L637 HydrophobicContact CE1-CD1 3.56Å; F571-L637 HydrophobicContact CE1-CG 4.06Å; F571-L637 HydrophobicContact CZ-CD1 3.67Å; Y579-L637 PolarHBondContact O-N 3.31Å; Y579-L637 VanDerWaalsContact O-N 3.09Å; F586-L637 HydrophobicContact CE1-CD1 3.74Å; F586-L637 HydrophobicContact CE1-CD2 4.28Å; F586-L637 HydrophobicContact CE1-CG 4.5Å; F586-L637 HydrophobicContact CE2-CD1 4.42Å; F586-L637 HydrophobicContact CZ-CD1 3.47Å; F586-L637 VanDerWaalsContact CZ-CD1 3.47Å; V611-L637 HydrophobicContact CG2-CD2 3.71Å; W622-L637 HydrophobicContact CB-CD2 4.23Å; P635-L637 HydrophobicContact CB-CD2 4.04Å; L637-F642 HydrophobicContact CB-CE2 3.83Å; L637-F642 HydrophobicContact CB-CZ 4.13Å; L637-F642 HydrophobicContact CD1-CE1 4.47Å; L637-F642 HydrophobicContact CD1-CE2 4.2Å; L637-F642 HydrophobicContact CD1-CZ 3.7Å; L637-F642 HydrophobicContact CG-CZ 4.35Å; L637-W656 PolarHBondContact O-NE1 3.04Å
638A94.4Very high92.6Very high35 Ų3544.8 Ų44.829%0.28923%0.226SC..  trans-91.3110174.800000110.5W622 K640 N641 F642W622-A638 PolarHBondContact O-N 3.35Å; A638-K640 HydrophobicContact CB-CG 4.29Å; A638-K640 PolarHBondContact O-N 3.29Å; A638-N641 WeakPolarHBondContact O-CB 3.4Å; A638-N641 PolarHBondContact O-N 3.34Å; A638-F642 WeakPolarHBondContact O-CD2 3.36Å
639I95.4Very high92.7Very high4 Ų445.4 Ų45.42%0.02124%0.237CC..G310 helixtrans-52.9-28.9-173.9-160.759.3000114.9N641 F642 L644 V653 K655 W656 V659I639-N641 PolarHBondContact O-N 3.3Å; I639-F642 PolarHBondContact O-N 3.35Å; I639-L644 HydrophobicContact CD1-CD2 3.87Å; I639-V653 HydrophobicContact CB-CG2 4.36Å; I639-V653 HydrophobicContact CG1-CG2 3.41Å; I639-V653 VanDerWaalsContact CG1-CG2 3.41Å; I639-V653 HydrophobicContact CG2-CG2 4Å; I639-K655 VanDerWaalsContact CG2-C 3.41Å; I639-W656 HydrophobicContact CB-CD2 3.77Å; I639-W656 HydrophobicContact CB-CE3 4.37Å; I639-W656 HydrophobicContact CB-CG 3.99Å; I639-W656 HydrophobicContact CB-CZ2 4.15Å; I639-W656 HydrophobicContact CD1-CD2 4.23Å; I639-W656 HydrophobicContact CD1-CE3 4.03Å; I639-W656 HydrophobicContact CD1-CH2 3.67Å; I639-W656 HydrophobicContact CD1-CZ2 3.89Å; I639-W656 HydrophobicContact CD1-CZ3 3.75Å; I639-W656 HydrophobicContact CG1-CD2 4.17Å; I639-W656 HydrophobicContact CG1-CE3 4.26Å; I639-W656 HydrophobicContact CG1-CZ3 4.48Å; I639-W656 HydrophobicContact CG2-CD2 4.39Å; I639-W656 HydrophobicContact CG2-CG 4.11Å; I639-V659 HydrophobicContact CD1-CG1 4.41Å; I639-V659 HydrophobicContact CG1-CG1 4.11Å
640K93.9Very high93.2Very high122 Ų12241.7 Ų41.753%0.5322%0.223SC..G310 helixtrans-58.9-20176.968178.2-177.8177.40113.5R559 A638 F642R559-K640 VanDerWaalsContact CD-O 3.22Å; R559-K640 WeakPolarHBondContact CD-O 3.33Å; R559-K640 PolarHBondContact NH1-O 3.34Å; A638-K640 HydrophobicContact CB-CG 4.29Å; A638-K640 PolarHBondContact O-N 3.29Å; K640-F642 VanDerWaalsContact C-N 3.29Å
641N95.5Very high93.8Very high26 Ų2635.6 Ų35.614%0.13920%0.199CC..G310 helixtrans-87.82.2179.4-63.6-30.7000112.9R559 D621 W622 A638 I639R559-N641 WeakPolarHBondContact CB-O 3.37Å; R559-N641 PolarHBondContact N-O 3.37Å; R559-N641 VanDerWaalsContact N-O 3.12Å; D621-N641 PolarHBondContact O-ND2 3.03Å; D621-N641 VanDerWaalsContact O-ND2 3.09Å; W622-N641 PolarHBondContact O-ND2 3.42Å; W622-N641 VanDerWaalsContact O-ND2 3.15Å; A638-N641 WeakPolarHBondContact O-CB 3.4Å; A638-N641 PolarHBondContact O-N 3.34Å; I639-N641 PolarHBondContact O-N 3.3Å
642F96.9Very high94.4Very high1 Ų133.3 Ų33.30%0.00419%0.186CC..EExtended strand (participates in β ladder)trans-126.2159-177.1-56.6-86.7000111.9I556 L557 V565 W622 L637 A638 I639 K640I556-F642 HydrophobicContact CG2-CB 3.79Å; I556-F642 HydrophobicContact CG2-CD1 3.57Å; I556-F642 HydrophobicContact CG2-CE1 4.33Å; I556-F642 HydrophobicContact CG2-CG 3.75Å; L557-F642 CarbonylContact O-C 3.59Å; L557-F642 WeakPolarHBondContact O-CA 3.48Å; L557-F642 WeakPolarHBondContact O-CB 3.23Å; V565-F642 HydrophobicContact CG2-CD1 3.95Å; V565-F642 HydrophobicContact CG2-CE1 3.85Å; W622-F642 HydrophobicContact CB-CE1 4.46Å; W622-F642 HydrophobicContact CB-CE2 4.19Å; W622-F642 HydrophobicContact CB-CZ 3.61Å; W622-F642 AromaticContact CD1-CE1 3.86Å; W622-F642 AromaticContact CD1-CZ 3.72Å; W622-F642 AromaticContact CD2-CE1 3.59Å; W622-F642 HydrophobicContact CD2-CE1 3.59Å; W622-F642 AromaticContact CD2-CZ 3.61Å; W622-F642 HydrophobicContact CD2-CZ 3.61Å; W622-F642 AromaticContact CE2-CE1 3.67Å; W622-F642 HydrophobicContact CE3-CE1 4.11Å; W622-F642 HydrophobicContact CE3-CZ 4.13Å; W622-F642 AromaticContact CG-CE1 3.75Å; W622-F642 HydrophobicContact CG-CE1 3.75Å; W622-F642 HydrophobicContact CG-CE2 4.2Å; W622-F642 AromaticContact CG-CZ 3.35Å; W622-F642 HydrophobicContact CG-CZ 3.35Å; W622-F642 HydrophobicContact CZ2-CE1 4.28Å; W622-F642 AromaticContact NE1-CE1 3.8Å; L637-F642 HydrophobicContact CB-CE2 3.83Å; L637-F642 HydrophobicContact CB-CZ 4.13Å; L637-F642 HydrophobicContact CD1-CE1 4.47Å; L637-F642 HydrophobicContact CD1-CE2 4.2Å; L637-F642 HydrophobicContact CD1-CZ 3.7Å; L637-F642 HydrophobicContact CG-CZ 4.35Å; A638-F642 WeakPolarHBondContact O-CD2 3.36Å; I639-F642 PolarHBondContact O-N 3.35Å; K640-F642 VanDerWaalsContact C-N 3.29Å
643A97.1Very high94.7Very high0 Ų034 Ų340%019%0.189CC..EExtended strand (participates in β ladder)trans-107.7153162.700000108.9V275 L557 R650 T652V275-A643 HydrophobicContact CG1-CB 3.47Å; V275-A643 VanDerWaalsContact CG1-CB 3.47Å; L557-A643 HydrophobicContact CB-CB 4.27Å; L557-A643 PolarHBondContact N-O 2.94Å; L557-A643 PolarHBondContact O-N 2.89Å; A643-R650 HydrophobicContact CB-CG 4.13Å; A643-T652 HydrophobicContact CB-CG2 4.4Å
644L96.8Very high94.7Very high1 Ų136.8 Ų36.81%0.00520%0.198CC..EExtended strand (participates in β ladder)trans-114.7115.9179.6-48.1178.3000108.2I554 I556 I639 T646 R650 I651 V653 V659I554-L644 HydrophobicContact CG2-CB 4.15Å; I554-L644 HydrophobicContact CG2-CD2 4.45Å; I556-L644 HydrophobicContact CD1-CD2 3.23Å; I639-L644 HydrophobicContact CD1-CD2 3.87Å; L644-T646 HydrophobicContact CB-CG2 4.41Å; L644-R650 CarbonylContact O-C 3.53Å; L644-R650 VanDerWaalsContact O-CA 3.31Å; L644-R650 WeakPolarHBondContact O-CA 3.49Å; L644-I651 HydrophobicContact CB-CG1 3.9Å; L644-I651 HydrophobicContact CD1-CD1 4.39Å; L644-I651 HydrophobicContact CD1-CG1 4.36Å; L644-I651 HydrophobicContact CG-CG1 4.49Å; L644-I651 PolarHBondContact N-O 3.48Å; L644-I651 PolarHBondContact O-N 2.96Å; L644-V653 HydrophobicContact CD1-CG1 4.25Å; L644-V653 HydrophobicContact CD1-CG2 3.93Å; L644-V659 HydrophobicContact CD1-CB 4.49Å; L644-V659 HydrophobicContact CD1-CG1 4.07Å
645E97.1Very high94.6Very high38 Ų3842.5 Ų42.518%0.17822%0.223CC..EExtended strand (participates in β ladder)trans-83.3113.8167.8-161.773.4-122.900107.6I554 R555 L557 R650I554-E645 WeakPolarHBondContact CA-O 3.34Å; R555-E645 HydrophobicContact CB-CB 4.05Å; R555-E645 PolarHBondContact N-O 3Å; R555-E645 PolarHBondContact O-N 3.43Å; L557-E645 HydrophobicContact CD1-CB 4.1Å; E645-R650 IonicContact OE2-CZ 2.74Å; E645-R650 IonicContact OE2-NE 3.39Å; E645-R650 PolarHBondContact OE2-NE 2.85Å; E645-R650 IonicContact OE2-NH2 3.85Å; E645-R650 PolarHBondContact OE2-NH2 3.12Å; E645-R650 VanDerWaalsContact OE2-NH2 3.1Å
646T95.3Very high94.4Very high12 Ų1243.3 Ų43.37%0.07423%0.225CC..EExtended strand (participates in β ladder)trans-110.1168.4176.5910000110.1I554 L644 D648 G649 I651 P660I554-T646 HydrophobicContact CD1-CG2 3.83Å; L644-T646 HydrophobicContact CB-CG2 4.41Å; T646-D648 PolarHBondContact O-N 3.2Å; T646-D648 VanDerWaalsContact O-N 3.13Å; T646-D648 PolarHBondContact OG1-N 3.23Å; T646-D648 VanDerWaalsContact OG1-N 3.07Å; T646-G649 PolarHBondContact N-O 3.35Å; T646-G649 VanDerWaalsContact N-O 3.1Å; T646-G649 PolarHBondContact O-N 3.34Å; T646-G649 PolarHBondContact OG1-O 2.98Å; T646-G649 VanDerWaalsContact OG1-O 3.14Å; T646-I651 HydrophobicContact CG2-CD1 3.99Å; T646-I651 HydrophobicContact CG2-CG1 4.01Å; T646-P660 HydrophobicContact CG2-CG 4.15Å
647P94.3Very high94Very high86 Ų8648.4 Ų48.456%0.55825%0.246SC*.THydrogen-bonded Turntrans-56.1-25.1171.7-26.936.1000114.3
648D92.7Very high93.8Very high101 Ų10150.9 Ų50.954%0.5426%0.26SS..THydrogen-bonded Turntrans-91-2.9179.8-60.7-22.7000112.6R548 H549 T646R548-D648 IonicContact CZ-OD2 2.79Å; R548-D648 IonicContact NE-OD2 3.13Å; R548-D648 PolarHBondContact NE-OD2 3.03Å; R548-D648 IonicContact NH2-OD2 2.66Å; R548-D648 PolarHBondContact NH2-OD2 3.24Å; H549-D648 IonicContact CE1-OD1 2.65Å; H549-D648 IonicContact CE1-OD2 3.64Å; H549-D648 PolarHBondContact CE1-OD2 3.22Å; H549-D648 VanDerWaalsContact CE1-OD2 3.28Å; H549-D648 IonicContact NE2-OD2 3.24Å; H549-D648 PolarHBondContact NE2-OD2 3.01Å; T646-D648 PolarHBondContact O-N 3.2Å; T646-D648 VanDerWaalsContact O-N 3.13Å; T646-D648 PolarHBondContact OG1-N 3.23Å; T646-D648 VanDerWaalsContact OG1-N 3.07Å
649G93.1Very high93.8Very high28 Ų2849.4 Ų49.429%0.28925%0.247SC..EExtended strand (participates in β ladder)trans117.3179.6-178.200000113.9T646T646-G649 PolarHBondContact N-O 3.35Å; T646-G649 VanDerWaalsContact N-O 3.1Å; T646-G649 PolarHBondContact O-N 3.34Å; T646-G649 PolarHBondContact OG1-O 2.98Å; T646-G649 VanDerWaalsContact OG1-O 3.14Å
650R95.6Very high93.7Very high27 Ų2749.5 Ų49.510%0.10225%0.248CC..EExtended strand (participates in β ladder)trans-82.4130-174.5-166.2-175.7-69.8175.28.5112.6V275 S276 D278 L557 A643 L644 E645V275-R650 WeakPolarHBondContact O-CD 3.28Å; S276-R650 WeakPolarHBondContact CA-O 3.45Å; S276-R650 VanDerWaalsContact CB-O 3.26Å; S276-R650 WeakPolarHBondContact CB-O 3.34Å; D278-R650 IonicContact OD1-CZ 3.67Å; D278-R650 IonicContact OD1-NH1 2.61Å; D278-R650 PolarHBondContact OD1-NH1 2.87Å; D278-R650 IonicContact OD1-NH2 2.94Å; D278-R650 PolarHBondContact OD1-NH2 3.49Å; D278-R650 IonicContact OD2-CZ 3.23Å; D278-R650 IonicContact OD2-NH1 2.68Å; D278-R650 IonicContact OD2-NH2 3.32Å; D278-R650 PolarHBondContact OD2-NH2 3.26Å; L557-R650 HydrophobicContact CD1-CG 4.43Å; L557-R650 VanDerWaalsContact CD1-NE 3.26Å; A643-R650 HydrophobicContact CB-CG 4.13Å; L644-R650 CarbonylContact O-C 3.53Å; L644-R650 VanDerWaalsContact O-CA 3.31Å; L644-R650 WeakPolarHBondContact O-CA 3.49Å; E645-R650 IonicContact OE2-CZ 2.74Å; E645-R650 IonicContact OE2-NE 3.39Å; E645-R650 PolarHBondContact OE2-NE 2.85Å; E645-R650 IonicContact OE2-NH2 3.85Å; E645-R650 PolarHBondContact OE2-NH2 3.12Å; E645-R650 VanDerWaalsContact OE2-NH2 3.1Å
651I94.2Very high93.8Very high62 Ų6243.8 Ų43.832%0.31822%0.223SC..EExtended strand (participates in β ladder)trans-128164.4179.366.9172.8000112.1L644 T646 V653 P660L644-I651 HydrophobicContact CB-CG1 3.9Å; L644-I651 HydrophobicContact CD1-CD1 4.39Å; L644-I651 HydrophobicContact CD1-CG1 4.36Å; L644-I651 HydrophobicContact CG-CG1 4.49Å; L644-I651 PolarHBondContact N-O 3.48Å; L644-I651 PolarHBondContact O-N 2.96Å; T646-I651 HydrophobicContact CG2-CD1 3.99Å; T646-I651 HydrophobicContact CG2-CG1 4.01Å; I651-V653 HydrophobicContact CD1-CG1 4.35Å; I651-P660 HydrophobicContact CD1-CG 4.01Å
652T93.4Very high93.6Very high33 Ų3348.3 Ų48.320%0.20225%0.245CC..  trans-121.6147.1166.463.80000110.3V275 A643V275-T652 HydrophobicContact CB-CG2 3.89Å; V275-T652 HydrophobicContact CG1-CG2 3.39Å; V275-T652 HydrophobicContact CG2-CG2 4.43Å; A643-T652 HydrophobicContact CB-CG2 4.4Å
653V92.4Very high93.4Very high13 Ų1349.3 Ų49.38%0.07925%0.251CS..  trans-130.4148.7175.1-61.40000110.1I639 L644 I651 D658 V659I639-V653 HydrophobicContact CB-CG2 4.36Å; I639-V653 HydrophobicContact CG1-CG2 3.41Å; I639-V653 VanDerWaalsContact CG1-CG2 3.41Å; I639-V653 HydrophobicContact CG2-CG2 4Å; L644-V653 HydrophobicContact CD1-CG1 4.25Å; L644-V653 HydrophobicContact CD1-CG2 3.93Å; I651-V653 HydrophobicContact CD1-CG1 4.35Å; V653-D658 HydrophobicContact CB-CB 4.36Å; V653-D658 HydrophobicContact CG1-CB 4.47Å; V653-V659 HydrophobicContact CG2-CG1 3.93Å
654K90.6Very high93.2Very high152 Ų15254.8 Ų54.866%0.66128%0.277SS*.SBendtrans-87-28.7-179.9-69.6-175.8179.9177.70112.8
655K91.4Very high92.9Very high122 Ų12260.9 Ų60.953%0.5331%0.305SS..SBendtrans-139.6148.4-174.6-59.6179.7176-175.90110.3I639 K657 D658I639-K655 VanDerWaalsContact CG2-C 3.41Å; K655-K657 VanDerWaalsContact C-N 3.25Å; K655-K657 HydrophobicContact CB-CG 3.97Å; K655-K657 PolarHBondContact O-N 3.23Å; K655-D658 WeakPolarHBondContact O-CB 3.48Å; K655-D658 PolarHBondContact O-N 3.45Å
656W92.4Very high92.7Very high23 Ų2360.2 Ų60.29%0.08730%0.302CS..G310 helixtrans-59.6-36-178.8-80.6108.2000113F571 Y579 L637 I639 D658 V659 F661 V663F571-W656 HydrophobicContact CB-CH2 4.25Å; F571-W656 HydrophobicContact CB-CZ3 4.39Å; F571-W656 AromaticContact CD1-CH2 3.34Å; F571-W656 HydrophobicContact CD1-CH2 3.34Å; F571-W656 AromaticContact CD1-CZ2 3.86Å; F571-W656 HydrophobicContact CD1-CZ2 3.86Å; F571-W656 HydrophobicContact CD1-CZ3 4.26Å; F571-W656 HydrophobicContact CD2-CH2 4.18Å; F571-W656 AromaticContact CE1-CH2 3.63Å; F571-W656 HydrophobicContact CE1-CH2 3.63Å; F571-W656 AromaticContact CE1-CZ2 3.94Å; F571-W656 HydrophobicContact CE1-CZ2 3.94Å; F571-W656 HydrophobicContact CE2-CH2 4.45Å; F571-W656 AromaticContact CG-CH2 3.63Å; F571-W656 HydrophobicContact CG-CH2 3.63Å; F571-W656 HydrophobicContact CG-CZ3 4.18Å; F571-W656 HydrophobicContact CZ-CH2 4.19Å; Y579-W656 HydrophobicContact CD1-CB 3.8Å; Y579-W656 AromaticContact CD1-CD2 3.4Å; Y579-W656 HydrophobicContact CD1-CD2 3.4Å; Y579-W656 AromaticContact CD1-CE2 3.97Å; Y579-W656 AromaticContact CD1-CE3 3.53Å; Y579-W656 HydrophobicContact CD1-CE3 3.53Å; Y579-W656 AromaticContact CD1-CG 3.56Å; Y579-W656 HydrophobicContact CD1-CG 3.56Å; Y579-W656 HydrophobicContact CD1-CZ3 4.21Å; Y579-W656 HydrophobicContact CD2-CB 3.79Å; Y579-W656 AromaticContact CD2-CD1 3.28Å; Y579-W656 HydrophobicContact CD2-CD2 4.03Å; Y579-W656 AromaticContact CD2-CG 3.45Å; Y579-W656 HydrophobicContact CD2-CG 3.45Å; Y579-W656 VanDerWaalsContact CD2-CG 3.45Å; Y579-W656 AromaticContact CD2-NE1 3.78Å; Y579-W656 HydrophobicContact CE1-CB 3.45Å; Y579-W656 VanDerWaalsContact CE1-CB 3.45Å; Y579-W656 AromaticContact CE1-CD2 3.98Å; Y579-W656 HydrophobicContact CE1-CD2 3.98Å; Y579-W656 HydrophobicContact CE1-CE3 4.04Å; Y579-W656 AromaticContact CE1-CG 3.77Å; Y579-W656 HydrophobicContact CE1-CG 3.77Å; Y579-W656 HydrophobicContact CE2-CB 3.44Å; Y579-W656 VanDerWaalsContact CE2-CB 3.44Å; Y579-W656 AromaticContact CE2-CD1 3.81Å; Y579-W656 AromaticContact CE2-CG 3.69Å; Y579-W656 HydrophobicContact CE2-CG 3.69Å; Y579-W656 HydrophobicContact CG-CB 3.96Å; Y579-W656 AromaticContact CG-CD1 3.47Å; Y579-W656 VanDerWaalsContact CG-CD1 3.47Å; Y579-W656 AromaticContact CG-CD2 3.43Å; Y579-W656 HydrophobicContact CG-CD2 3.43Å; Y579-W656 VanDerWaalsContact CG-CD2 3.43Å; Y579-W656 AromaticContact CG-CE2 3.58Å; Y579-W656 HydrophobicContact CG-CE3 4.04Å; Y579-W656 AromaticContact CG-CG 3.39Å; Y579-W656 HydrophobicContact CG-CG 3.39Å; Y579-W656 HydrophobicContact CG-CZ2 4.3Å; Y579-W656 AromaticContact CG-NE1 3.59Å; Y579-W656 AromaticContact CZ-CG 3.83Å; L637-W656 PolarHBondContact O-NE1 3.04Å; I639-W656 HydrophobicContact CB-CD2 3.77Å; I639-W656 HydrophobicContact CB-CE3 4.37Å; I639-W656 HydrophobicContact CB-CG 3.99Å; I639-W656 HydrophobicContact CB-CZ2 4.15Å; I639-W656 HydrophobicContact CD1-CD2 4.23Å; I639-W656 HydrophobicContact CD1-CE3 4.03Å; I639-W656 HydrophobicContact CD1-CH2 3.67Å; I639-W656 HydrophobicContact CD1-CZ2 3.89Å; I639-W656 HydrophobicContact CD1-CZ3 3.75Å; I639-W656 HydrophobicContact CG1-CD2 4.17Å; I639-W656 HydrophobicContact CG1-CE3 4.26Å; I639-W656 HydrophobicContact CG1-CZ3 4.48Å; I639-W656 HydrophobicContact CG2-CD2 4.39Å; I639-W656 HydrophobicContact CG2-CG 4.11Å; W656-D658 PolarHBondContact O-N 3.03Å; W656-V659 HydrophobicContact CE3-CG1 4Å; W656-V659 WeakPolarHBondContact O-CG1 3.21Å; W656-V659 WeakPolarHBondContact O-CG2 3.42Å; W656-V659 PolarHBondContact O-N 3.43Å; W656-V659 VanDerWaalsContact O-N 3.09Å; W656-F661 HydrophobicContact CZ3-CZ 4.32Å; W656-V663 HydrophobicContact CE3-CG2 4.38Å; W656-V663 HydrophobicContact CZ3-CG2 4.49Å
657K87.1Confident92.3Very high127 Ų12762.3 Ų62.355%0.55232%0.315SS*.G310 helixtrans-58.6-15.3174.868.4170.9-1681690115K655K655-K657 VanDerWaalsContact C-N 3.25Å; K655-K657 HydrophobicContact CB-CG 3.97Å; K655-K657 PolarHBondContact O-N 3.23Å
658D90.6Very high91.9Very high55 Ų5559.9 Ų59.929%0.29430%0.296SS..G310 helixtrans-99.3-0.1-177-55.4-43.1000112.7K545 V653 K655 W656K545-D658 VanDerWaalsContact CE-O 3.29Å; K545-D658 WeakPolarHBondContact CE-O 3.41Å; K545-D658 PolarHBondContact NZ-O 2.9Å; V653-D658 HydrophobicContact CB-CB 4.36Å; V653-D658 HydrophobicContact CG1-CB 4.47Å; K655-D658 WeakPolarHBondContact O-CB 3.48Å; K655-D658 PolarHBondContact O-N 3.45Å; W656-D658 PolarHBondContact O-N 3.03Å
659V93.7Very high91.5Very high5 Ų560.8 Ų60.83%0.0330%0.296CS..  trans-65.3149.3176.8-62.30000111.6I639 L644 V653 W656 F661 V663I639-V659 HydrophobicContact CD1-CG1 4.41Å; I639-V659 HydrophobicContact CG1-CG1 4.11Å; L644-V659 HydrophobicContact CD1-CB 4.49Å; L644-V659 HydrophobicContact CD1-CG1 4.07Å; V653-V659 HydrophobicContact CG2-CG1 3.93Å; W656-V659 HydrophobicContact CE3-CG1 4Å; W656-V659 WeakPolarHBondContact O-CG1 3.21Å; W656-V659 WeakPolarHBondContact O-CG2 3.42Å; W656-V659 PolarHBondContact O-N 3.43Å; W656-V659 VanDerWaalsContact O-N 3.09Å; V659-F661 VanDerWaalsContact C-N 3.25Å; V659-F661 HydrophobicContact CB-CD1 3.9Å; V659-F661 HydrophobicContact CB-CE1 3.74Å; V659-F661 HydrophobicContact CB-CZ 4.49Å; V659-F661 HydrophobicContact CG1-CE1 4.12Å; V659-F661 HydrophobicContact CG2-CD1 4.06Å; V659-F661 HydrophobicContact CG2-CE1 4.01Å; V659-F661 HydrophobicContact CG2-CG 4.47Å; V659-F661 HydrophobicContact CG2-CZ 4.38Å; V659-F661 WeakPolarHBondContact CG2-O 3.38Å; V659-F661 PolarHBondContact O-N 2.93Å; V659-V663 HydrophobicContact CG2-CG2 4.32Å
660P94.5Very high91.1Very high6 Ų664.2 Ų64.24%0.03931%0.305CS..SBendtrans-9023.6-17639.2-39.1000113.6K545 H549 T646 I651K545-P660 CarbonylContact O-C 3.43Å; K545-P660 WeakPolarHBondContact O-CA 3.34Å; H549-P660 PolarHBondContact N-O 3.36Å; T646-P660 HydrophobicContact CG2-CG 4.15Å; I651-P660 HydrophobicContact CD1-CG 4.01Å
661F94.3Very high90.6Very high1 Ų164.4 Ų64.40%0.00431%0.306CS..SBendtrans-142.5159.3179.167.8-84.2000110K546 H549 A551 I554 G568 W656 V659 V663K546-F661 CarbonylContact O-C 3.5Å; K546-F661 WeakPolarHBondContact O-CA 3.49Å; H549-F661 WeakPolarHBondContact O-CB 3.45Å; A551-F661 HydrophobicContact CB-CD2 3.6Å; A551-F661 HydrophobicContact CB-CE2 4.18Å; A551-F661 HydrophobicContact CB-CG 4.37Å; I554-F661 HydrophobicContact CB-CD1 4.32Å; I554-F661 HydrophobicContact CB-CE1 4.47Å; I554-F661 HydrophobicContact CG1-CB 4.27Å; I554-F661 HydrophobicContact CG1-CD1 3.82Å; I554-F661 HydrophobicContact CG1-CE1 4.44Å; I554-F661 HydrophobicContact CG1-CG 4.2Å; I554-F661 HydrophobicContact CG2-CD1 4.26Å; I554-F661 HydrophobicContact CG2-CE1 4.08Å; G568-F661 WeakPolarHBondContact O-CE2 3.43Å; W656-F661 HydrophobicContact CZ3-CZ 4.32Å; V659-F661 VanDerWaalsContact C-N 3.25Å; V659-F661 HydrophobicContact CB-CD1 3.9Å; V659-F661 HydrophobicContact CB-CE1 3.74Å; V659-F661 HydrophobicContact CB-CZ 4.49Å; V659-F661 HydrophobicContact CG1-CE1 4.12Å; V659-F661 HydrophobicContact CG2-CD1 4.06Å; V659-F661 HydrophobicContact CG2-CE1 4.01Å; V659-F661 HydrophobicContact CG2-CG 4.47Å; V659-F661 HydrophobicContact CG2-CZ 4.38Å; V659-F661 WeakPolarHBondContact CG2-O 3.38Å; V659-F661 PolarHBondContact O-N 2.93Å; F661-V663 HydrophobicContact CD2-CG2 4.27Å; F661-V663 HydrophobicContact CE2-CG2 3.73Å; F661-V663 HydrophobicContact CZ-CG2 4.28Å
662M92.4Very high90.2Very high121 Ų12162 Ų6260%0.59629%0.294SS*.PPolyproline II helixtrans-83129175.8-168.5170.9-141.500109.6K546K546-M662 PolarHBondContact O-N 3.34Å
663V92.9Very high89.6Confident23 Ų2363.4 Ų63.414%0.13931%0.306CS..PPolyproline II helixtrans-96.4119.9170.5-176.20000107.2F571 L573 Y579 W656 V659 F661F571-V663 HydrophobicContact CB-CG1 4.39Å; F571-V663 WeakPolarHBondContact O-CG1 3.45Å; L573-V663 HydrophobicContact CB-CG1 4.18Å; Y579-V663 HydrophobicContact CD1-CB 4.43Å; Y579-V663 HydrophobicContact CD1-CG1 4Å; Y579-V663 HydrophobicContact CD1-CG2 4.24Å; Y579-V663 HydrophobicContact CE1-CB 4.21Å; Y579-V663 HydrophobicContact CE1-CG1 4.2Å; Y579-V663 HydrophobicContact CE1-CG2 4.11Å; W656-V663 HydrophobicContact CE3-CG2 4.38Å; W656-V663 HydrophobicContact CZ3-CG2 4.49Å; V659-V663 HydrophobicContact CG2-CG2 4.32Å; F661-V663 HydrophobicContact CD2-CG2 4.27Å; F661-V663 HydrophobicContact CE2-CG2 3.73Å; F661-V663 HydrophobicContact CZ-CG2 4.28Å
664E92.3Very high89.2Confident115 Ų11567.7 Ų67.754%0.53733%0.328SS..EExtended strand (participates in β ladder)trans-72.6153.4179.8-67.7173.8-169.600111.6K572 L573K572-E664 CarbonylContact C-O 3.55Å; K572-E664 VanDerWaalsContact CA-O 3.3Å; K572-E664 WeakPolarHBondContact CA-O 3.35Å; K572-E664 HydrophobicContact CD-CB 3.95Å; K572-E664 IonicContact NZ-OE2 3.84Å; K572-E664 PolarHBondContact NZ-OE2 3.07Å; L573-E664 PolarHBondContact N-O 2.63Å
665E91.9Very high88.6Confident129 Ų12964 Ų6460%0.60331%0.312SS*.EExtended strand (participates in β ladder)trans-68.4144.2174.9-68.8-173.9177.800111
666F90.9Very high88Confident23 Ų2362 Ų6210%0.10130%0.304CS..PPolyproline II helixtrans-79.6127.6172.2177-90.8000109.7K572 L573 L574 V580 V582 Y628 L634 F668 Y671K572-F666 HydrophobicContact CB-CB 3.81Å; K572-F666 HydrophobicContact CB-CD2 4.24Å; L573-F666 PolarHBondContact O-N 3.22Å; L574-F666 HydrophobicContact CB-CB 4.19Å; L574-F666 HydrophobicContact CD1-CB 4.25Å; L574-F666 HydrophobicContact CD1-CD1 3.43Å; L574-F666 VanDerWaalsContact CD1-CD1 3.43Å; L574-F666 HydrophobicContact CD1-CE1 4.05Å; L574-F666 HydrophobicContact CD1-CG 4.06Å; V580-F666 HydrophobicContact CG2-CD2 4.33Å; V582-F666 HydrophobicContact CG1-CD2 3.88Å; V582-F666 HydrophobicContact CG1-CE2 4Å; Y628-F666 HydrophobicContact CD1-CE1 4.05Å; Y628-F666 AromaticContact CE1-CE1 3.97Å; Y628-F666 HydrophobicContact CE1-CE1 3.97Å; L634-F666 HydrophobicContact CD1-CD2 4.4Å; L634-F666 HydrophobicContact CD1-CE1 4.45Å; L634-F666 HydrophobicContact CD1-CE2 3.76Å; L634-F666 HydrophobicContact CD1-CZ 3.79Å; F666-F668 HydrophobicContact CE1-CB 4.17Å; F666-F668 HydrophobicContact CE1-CD2 4.33Å; F666-F668 HydrophobicContact CZ-CD2 4.39Å; F666-Y671 AromaticContact CE2-CD2 3.89Å; F666-Y671 HydrophobicContact CE2-CD2 3.89Å; F666-Y671 AromaticContact CE2-CG 3.96Å; F666-Y671 HydrophobicContact CE2-CG 3.96Å; F666-Y671 HydrophobicContact CZ-CD2 4.3Å; F666-Y671 AromaticContact CZ-CG 3.95Å; F666-Y671 HydrophobicContact CZ-CG 3.95Å
667T88.1Confident87Confident56 Ų5664.1 Ų64.134%0.34432%0.32SS..  trans-117.7128.7170.851.80000109.3E669 Q670 Y671T667-E669 VanDerWaalsContact C-N 3.31Å; T667-E669 PolarHBondContact O-N 3.06Å; T667-Q670 PolarHBondContact O-N 3.03Å; T667-Q670 WeakPolarHBondContact OG1-CB 3.47Å; T667-Q670 PolarHBondContact OG1-OE1 2.81Å; T667-Y671 PolarHBondContact O-N 3.2Å; T667-Y671 VanDerWaalsContact O-N 3.1Å
668F85.6Confident86.3Confident36 Ų3664.7 Ų64.716%0.15833%0.329CS..Hα-helixtrans-69.4-34.6-176.3-174.7-109.1000111.3Y628 R629 V631 F666 Y671 C672Y628-F668 AromaticContact CD1-CD2 3.75Å; Y628-F668 HydrophobicContact CD1-CD2 3.75Å; Y628-F668 HydrophobicContact CD1-CE2 4.15Å; Y628-F668 HydrophobicContact CE1-CB 4.21Å; Y628-F668 AromaticContact CE1-CD2 3.74Å; Y628-F668 HydrophobicContact CE1-CD2 3.74Å; Y628-F668 HydrophobicContact CE1-CE2 4.45Å; Y628-F668 HydrophobicContact CE1-CG 4.17Å; R629-F668 HydrophobicContact CB-CE2 4.16Å; R629-F668 HydrophobicContact CB-CZ 4.13Å; V631-F668 HydrophobicContact CB-CZ 4.45Å; F666-F668 HydrophobicContact CE1-CB 4.17Å; F666-F668 HydrophobicContact CE1-CD2 4.33Å; F666-F668 HydrophobicContact CZ-CD2 4.39Å; F668-Y671 PolarHBondContact O-N 2.99Å; F668-C672 VanDerWaalsContact CE1-SG 3.53Å; F668-C672 VanDerWaalsContact CZ-SG 3.51Å; F668-C672 WeakPolarHBondContact O-CB 3.35Å; F668-C672 PolarHBondContact O-N 3.42Å; F668-C672 PolarHBondContact O-SG 2.94Å; F668-C672 VanDerWaalsContact O-SG 3.39Å
669E84.4Confident84.9Confident119 Ų11968 Ų6856%0.55635%0.347SS*.Hα-helixtrans-61.6-45.8177.2-60.972.8-157.200111T667 C672 S673T667-E669 VanDerWaalsContact C-N 3.31Å; T667-E669 PolarHBondContact O-N 3.06Å; E669-C672 PolarHBondContact O-N 3.27Å; E669-S673 WeakPolarHBondContact O-CB 3.24Å; E669-S673 PolarHBondContact O-N 2.91Å
670Q84.6Confident83.2Confident101 Ų10173.7 Ų73.747%0.47237%0.371SS..Hα-helixtrans-66.7-43.2177.7-170.7169.51.500111.2T667 C672 S673 D674T667-Q670 PolarHBondContact O-N 3.03Å; T667-Q670 WeakPolarHBondContact OG1-CB 3.47Å; T667-Q670 PolarHBondContact OG1-OE1 2.81Å; Q670-C672 VanDerWaalsContact C-N 3.32Å; Q670-C672 PolarHBondContact O-N 3.03Å; Q670-S673 PolarHBondContact O-N 2.64Å; Q670-D674 WeakPolarHBondContact O-CB 3.33Å; Q670-D674 PolarHBondContact O-N 2.97Å
671Y85.8Confident81.1Confident31 Ų3183.1 Ų83.112%0.12242%0.421CS..Hα-helixtrans-57.5-45.4174.3179.4-93.2000111.8A632 L634 F666 T667 F668 D674 F675 F676A632-Y671 HydrophobicContact CB-CD1 4.08Å; A632-Y671 HydrophobicContact CB-CE1 3.41Å; A632-Y671 VanDerWaalsContact CB-CE1 3.41Å; L634-Y671 HydrophobicContact CD2-CE2 3.91Å; F666-Y671 AromaticContact CE2-CD2 3.89Å; F666-Y671 HydrophobicContact CE2-CD2 3.89Å; F666-Y671 AromaticContact CE2-CG 3.96Å; F666-Y671 HydrophobicContact CE2-CG 3.96Å; F666-Y671 HydrophobicContact CZ-CD2 4.3Å; F666-Y671 AromaticContact CZ-CG 3.95Å; F666-Y671 HydrophobicContact CZ-CG 3.95Å; T667-Y671 PolarHBondContact O-N 3.2Å; T667-Y671 VanDerWaalsContact O-N 3.1Å; F668-Y671 PolarHBondContact O-N 2.99Å; Y671-D674 PolarHBondContact O-N 2.95Å; Y671-F675 AromaticContact CD2-CD2 3.51Å; Y671-F675 HydrophobicContact CD2-CD2 3.51Å; Y671-F675 AromaticContact CD2-CE2 3.65Å; Y671-F675 HydrophobicContact CD2-CE2 3.65Å; Y671-F675 HydrophobicContact CE1-CD2 4.45Å; Y671-F675 AromaticContact CE2-CD2 3.45Å; Y671-F675 HydrophobicContact CE2-CD2 3.45Å; Y671-F675 VanDerWaalsContact CE2-CD2 3.45Å; Y671-F675 AromaticContact CE2-CE2 3.62Å; Y671-F675 HydrophobicContact CE2-CE2 3.62Å; Y671-F675 HydrophobicContact CE2-CG 4.38Å; Y671-F675 HydrophobicContact CG-CD2 4.07Å; Y671-F675 AromaticContact CZ-CD2 3.95Å; Y671-F675 VanDerWaalsContact O-CD2 3.25Å; Y671-F675 WeakPolarHBondContact O-CD2 3.45Å; Y671-F675 PolarHBondContact O-N 2.98Å; Y671-F675 VanDerWaalsContact O-N 3.1Å; Y671-F676 HydrophobicContact CE1-CE2 4.14Å
672C84.3Confident80.5Confident10 Ų1087.2 Ų87.27%0.06844%0.442CS..Hα-helixtrans-65.4-40.8176.6-720000111.9F668 E669 Q670 D674 F676 F680F668-C672 VanDerWaalsContact CE1-SG 3.53Å; F668-C672 VanDerWaalsContact CZ-SG 3.51Å; F668-C672 WeakPolarHBondContact O-CB 3.35Å; F668-C672 PolarHBondContact O-N 3.42Å; F668-C672 PolarHBondContact O-SG 2.94Å; F668-C672 VanDerWaalsContact O-SG 3.39Å; E669-C672 PolarHBondContact O-N 3.27Å; Q670-C672 VanDerWaalsContact C-N 3.32Å; Q670-C672 PolarHBondContact O-N 3.03Å; C672-D674 VanDerWaalsContact C-N 3.32Å; C672-D674 PolarHBondContact O-N 3.3Å; C672-F676 CarbonylContact O-C 3.43Å; C672-F676 VanDerWaalsContact O-CA 3.24Å; C672-F676 WeakPolarHBondContact O-CA 3.38Å; C672-F676 WeakPolarHBondContact O-CB 3.29Å; C672-F676 PolarHBondContact O-N 3.05Å; C672-F680 HydrophobicContact CB-CE2 3.58Å; C672-F680 HydrophobicContact CB-CZ 3.77Å
673S82.5Confident79.9Confident64 Ų6485.4 Ų85.445%0.44843%0.434SS..Hα-helixtrans-63.1-38.7177-1740000112.3E669 Q670E669-S673 WeakPolarHBondContact O-CB 3.24Å; E669-S673 PolarHBondContact O-N 2.91Å; Q670-S673 PolarHBondContact O-N 2.64Å
674D82.4Confident79.1Confident102 Ų10288.9 Ų88.955%0.54545%0.45SS..Hα-helixtrans-75.4-33.5-176.7-69.2-17.6000112.2Q670 Y671 C672Q670-D674 WeakPolarHBondContact O-CB 3.33Å; Q670-D674 PolarHBondContact O-N 2.97Å; Y671-D674 PolarHBondContact O-N 2.95Å; C672-D674 VanDerWaalsContact C-N 3.32Å; C672-D674 PolarHBondContact O-N 3.3Å
675F78.9Confident78.4Confident75 Ų7587.4 Ų87.433%0.32945%0.445SS..Hα-helixtrans-113.5-16.4-171.5-65.5-69.2000115.3V582 P584 Y671V582-F675 WeakPolarHBondContact O-CZ 3.23Å; P584-F675 HydrophobicContact CB-CE1 4.06Å; P584-F675 HydrophobicContact CG-CE1 3.71Å; P584-F675 HydrophobicContact CG-CZ 4.41Å; Y671-F675 AromaticContact CD2-CD2 3.51Å; Y671-F675 HydrophobicContact CD2-CD2 3.51Å; Y671-F675 AromaticContact CD2-CE2 3.65Å; Y671-F675 HydrophobicContact CD2-CE2 3.65Å; Y671-F675 HydrophobicContact CE1-CD2 4.45Å; Y671-F675 AromaticContact CE2-CD2 3.45Å; Y671-F675 HydrophobicContact CE2-CD2 3.45Å; Y671-F675 VanDerWaalsContact CE2-CD2 3.45Å; Y671-F675 AromaticContact CE2-CE2 3.62Å; Y671-F675 HydrophobicContact CE2-CE2 3.62Å; Y671-F675 HydrophobicContact CE2-CG 4.38Å; Y671-F675 HydrophobicContact CG-CD2 4.07Å; Y671-F675 AromaticContact CZ-CD2 3.95Å; Y671-F675 VanDerWaalsContact O-CD2 3.25Å; Y671-F675 WeakPolarHBondContact O-CD2 3.45Å; Y671-F675 PolarHBondContact O-N 2.98Å; Y671-F675 VanDerWaalsContact O-N 3.1Å
676F78.9Confident77.5Confident81 Ų8184.8 Ų84.836%0.35544%0.435SS..  trans-137.258.8178.1-54.7-83000110.3V631 Y671 C672 D678 L679V631-F676 HydrophobicContact CG1-CE2 4.19Å; V631-F676 HydrophobicContact CG1-CZ 4.32Å; Y671-F676 HydrophobicContact CE1-CE2 4.14Å; C672-F676 CarbonylContact O-C 3.43Å; C672-F676 VanDerWaalsContact O-CA 3.24Å; C672-F676 WeakPolarHBondContact O-CA 3.38Å; C672-F676 WeakPolarHBondContact O-CB 3.29Å; C672-F676 PolarHBondContact O-N 3.05Å; F676-D678 PolarHBondContact O-N 3.34Å; F676-L679 HydrophobicContact CB-CD1 3.48Å; F676-L679 VanDerWaalsContact CB-CD1 3.48Å; F676-L679 HydrophobicContact CB-CG 4Å; F676-L679 HydrophobicContact CG-CD1 4.04Å; F676-L679 WeakPolarHBondContact O-CB 3.14Å; F676-L679 PolarHBondContact O-N 2.76Å; F676-L679 VanDerWaalsContact O-N 3.08Å
677P70.8Confident76.6Confident67 Ų6788.9 Ų88.944%0.43546%0.457SS..G310 helixtrans-57.6-34.3-174.923.9-34000112.3L679 F680P677-L679 PolarHBondContact O-N 2.93Å; P677-F680 PolarHBondContact O-N 3.06Å
678D73.4Confident75.8Confident139 Ų13991.2 Ų91.274%0.74347%0.465SS*.G310 helixtrans-65.4-7.5179.9-50.7-27.3000114.5F676F676-D678 PolarHBondContact O-N 3.34Å
679L60.9Low75.1Confident125 Ų12595.5 Ų95.565%0.65449%0.489SS*.G310 helixtrans-83.8-13.9175.7-73.9172.8000113.6F676 P677F676-L679 HydrophobicContact CB-CD1 3.48Å; F676-L679 VanDerWaalsContact CB-CD1 3.48Å; F676-L679 HydrophobicContact CB-CG 4Å; F676-L679 HydrophobicContact CG-CD1 4.04Å; F676-L679 WeakPolarHBondContact O-CB 3.14Å; F676-L679 PolarHBondContact O-N 2.76Å; F676-L679 VanDerWaalsContact O-N 3.08Å; P677-L679 PolarHBondContact O-N 2.93Å
680F57.5Low74.3Confident124 Ų12493.5 Ų93.554%0.54448%0.483SS..  trans-110.32.6-175.5-66-83.1000114C672 P677C672-F680 HydrophobicContact CB-CE2 3.58Å; C672-F680 HydrophobicContact CB-CZ 3.77Å; P677-F680 PolarHBondContact O-N 3.06Å
681D51.3Low73.3Confident203 Ų20392.8 Ų92.8100%1.08648%0.484SS*.  trans-93.30175.4-79.3-23.7000113.3

Retrieved 681 of 681 residues in 1113.6 ms (Link to these results)