A0A087Y2P4_POEFO Loading...

dolichyl-phosphate-mannose--protein mannosyltransferase

AlphaFold DB , UniProt , Accession A0A087Y2P4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 741 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M35.6Very low57.4Low220 Ų22092.1 Ų92.1100%1.08448%0.479SS*.  01180-86.1177167.600108.1Q3M1-Q3 PolarHBondContact O-N 2.96Å
2A30.7Very low59.6Low111 Ų11184.6 Ų84.692%0.91744%0.44SS*.  trans-66.5113.8175.100000109
3Q40.9Very low61.4Low93 Ų9380.6 Ų80.644%0.43542%0.423SS..  trans-102.1127.2163.8-81-175.8-900108.3M1M1-Q3 PolarHBondContact O-N 2.96Å
4T45Very low63Low121 Ų12177.4 Ų77.474%0.74241%0.406SS*.  trans-34.5144.1168.221.60000113.4L6 Q378T4-L6 PolarHBondContact O-N 3.49Å; T4-Q378 PolarHBondContact O-NE2 3.33Å; T4-Q378 VanDerWaalsContact O-NE2 3.13Å
5E53Low64.3Low140 Ų14077.7 Ų77.765%0.65441%0.414SS*.  trans-37.3132.2176.6-68.7-170.4141.200112.1Y7 H10E5-Y7 PolarHBondContact O-N 2.93Å; E5-H10 IonicContact OE1-CE1 3.79Å; E5-H10 IonicContact OE1-NE2 2.66Å; E5-H10 IonicContact OE2-CD2 2.78Å; E5-H10 IonicContact OE2-CE1 3.79Å; E5-H10 IonicContact OE2-NE2 3.74Å; E5-H10 PolarHBondContact OE2-NE2 3.03Å
6L59.8Low65.2Low22 Ų2284 Ų8412%0.11544%0.437CS..  trans-56.8102.7174.5-85.3138.9000109.5T4 W8 D9 I130T4-L6 PolarHBondContact O-N 3.49Å; L6-W8 VanDerWaalsContact C-N 3.25Å; L6-W8 HydrophobicContact CD2-CH2 4Å; L6-W8 HydrophobicContact CD2-CZ2 3.35Å; L6-W8 PolarHBondContact O-N 2.78Å; L6-W8 VanDerWaalsContact O-N 3.12Å; L6-D9 HydrophobicContact CB-CB 3.77Å; L6-D9 VanDerWaalsContact O-CB 3.24Å; L6-D9 WeakPolarHBondContact O-CB 3.12Å; L6-D9 PolarHBondContact O-N 3.48Å; L6-I130 HydrophobicContact CD1-CG2 3.57Å; L6-I130 HydrophobicContact CD2-CG2 3.4Å; L6-I130 VanDerWaalsContact CD2-CG2 3.4Å; L6-I130 HydrophobicContact CG-CG2 4.12Å
7Y61.6Low66.3Low145 Ų14581.9 Ų81.957%0.56943%0.426SS*.THydrogen-bonded Turntrans-59.3-34.2-165-173.8-101.6000113.3E5 H11 Y433E5-Y7 PolarHBondContact O-N 2.93Å; Y7-H11 PolarHBondContact O-CD2 2.95Å; Y7-Y433 HydrophobicContact CD1-CE2 4.18Å; Y7-Y433 HydrophobicContact CE1-CD2 4.33Å; Y7-Y433 AromaticContact CE1-CE2 3.47Å; Y7-Y433 HydrophobicContact CE1-CE2 3.47Å; Y7-Y433 VanDerWaalsContact CE1-CE2 3.47Å; Y7-Y433 AromaticContact CE1-CZ 3.66Å
8W70.9Confident67.1Low7 Ų779.4 Ų79.43%0.02742%0.424CS..THydrogen-bonded Turntrans-81-17.8177.158.479.5000114.4L6 H10 H11 Q378 Y426L6-W8 VanDerWaalsContact C-N 3.25Å; L6-W8 HydrophobicContact CD2-CH2 4Å; L6-W8 HydrophobicContact CD2-CZ2 3.35Å; L6-W8 PolarHBondContact O-N 2.78Å; L6-W8 VanDerWaalsContact O-N 3.12Å; W8-H10 VanDerWaalsContact C-N 3.28Å; W8-H10 PolarHBondContact O-N 3.13Å; W8-H11 PolarHBondContact O-N 2.96Å; W8-H11 VanDerWaalsContact O-N 3.08Å; W8-Q378 HydrophobicContact CH2-CB 3.37Å; W8-Q378 HydrophobicContact CZ2-CB 4.29Å; W8-Q378 HydrophobicContact CZ3-CB 3.94Å; W8-Y426 HydrophobicContact CD2-CE2 4.4Å; W8-Y426 AromaticContact CE2-CE2 3.97Å; W8-Y426 AromaticContact CH2-CE2 3.95Å; W8-Y426 HydrophobicContact CH2-CE2 3.95Å; W8-Y426 AromaticContact CZ2-CD2 3.91Å; W8-Y426 HydrophobicContact CZ2-CD2 3.91Å; W8-Y426 AromaticContact CZ2-CE2 3.74Å; W8-Y426 HydrophobicContact CZ2-CE2 3.74Å; W8-Y426 HydrophobicContact CZ3-CE2 4.42Å
9D78.4Confident67.9Low21 Ų2177.8 Ų77.811%0.11242%0.423CS..G310 helixtrans-62.6-38.6-173.9-161.667.8000111L6 H11 I12 K147 T148L6-D9 HydrophobicContact CB-CB 3.77Å; L6-D9 VanDerWaalsContact O-CB 3.24Å; L6-D9 WeakPolarHBondContact O-CB 3.12Å; L6-D9 PolarHBondContact O-N 3.48Å; D9-H11 PolarHBondContact O-N 3.32Å; D9-I12 WeakPolarHBondContact O-CB 3.48Å; D9-I12 PolarHBondContact O-N 2.96Å; D9-I12 VanDerWaalsContact O-N 3.16Å; D9-K147 WeakPolarHBondContact O-CD 3.46Å; D9-K147 PolarHBondContact OD1-N 3.5Å; D9-K147 VanDerWaalsContact OD1-N 3.12Å; D9-K147 PolarHBondContact OD2-N 3.11Å; D9-T148 VanDerWaalsContact OD1-CB 3.31Å; D9-T148 WeakPolarHBondContact OD1-CB 3.41Å; D9-T148 PolarHBondContact OD1-N 2.84Å; D9-T148 PolarHBondContact OD1-OG1 3.29Å
10H75.9Confident68.9Low90 Ų9079.6 Ų79.642%0.41744%0.436SS..G310 helixtrans-58.9-29.2176.7-67.5-56.2000113.7E5 W8E5-H10 IonicContact OE1-CE1 3.79Å; E5-H10 IonicContact OE1-NE2 2.66Å; E5-H10 IonicContact OE2-CD2 2.78Å; E5-H10 IonicContact OE2-CE1 3.79Å; E5-H10 IonicContact OE2-NE2 3.74Å; E5-H10 PolarHBondContact OE2-NE2 3.03Å; W8-H10 VanDerWaalsContact C-N 3.28Å; W8-H10 PolarHBondContact O-N 3.13Å
11H79.4Confident69.9Low43 Ų4381.1 Ų81.120%0.19944%0.44CS..G310 helixtrans-80.8-15.5-177.2-67.1-84000113.5Y7 W8 D9 Y433 K439Y7-H11 PolarHBondContact O-CD2 2.95Å; W8-H11 PolarHBondContact O-N 2.96Å; W8-H11 VanDerWaalsContact O-N 3.08Å; D9-H11 PolarHBondContact O-N 3.32Å; H11-Y433 AromaticContact CD2-CD2 3.6Å; H11-Y433 AromaticContact CE1-CD2 3.93Å; H11-Y433 AromaticContact NE2-CD2 3.54Å; H11-Y433 AromaticContact NE2-CE2 3.99Å; H11-K439 WeakPolarHBondContact O-CE 3.26Å
12I83.8Confident72.5Confident2 Ų270.7 Ų70.71%0.0139%0.389CS..SBendtrans-64.4128.3177.1-63.2177.4000109.2D9 L14 K147 T148 L151D9-I12 WeakPolarHBondContact O-CB 3.48Å; D9-I12 PolarHBondContact O-N 2.96Å; D9-I12 VanDerWaalsContact O-N 3.16Å; I12-L14 HydrophobicContact CG2-CB 4.09Å; I12-L14 HydrophobicContact CG2-CD1 3.98Å; I12-L14 HydrophobicContact CG2-CG 3.9Å; I12-L14 PolarHBondContact O-N 3.12Å; I12-K147 HydrophobicContact CB-CB 4.07Å; I12-K147 HydrophobicContact CB-CD 4.3Å; I12-K147 HydrophobicContact CD1-CB 4.22Å; I12-K147 HydrophobicContact CG2-CB 4.17Å; I12-K147 PolarHBondContact O-NZ 3.05Å; I12-T148 HydrophobicContact CD1-CG2 4.43Å; I12-T148 WeakPolarHBondContact CD1-OG1 3.4Å; I12-L151 HydrophobicContact CG2-CD2 4.11Å
13P82.9Confident75.5Confident33 Ų3368.6 Ų68.621%0.21436%0.359CS..SBendtrans-78.643.5-175.935.5-37.9000112.4C443 L446P13-C443 HydrophobicContact CB-CB 3.87Å; P13-C443 HydrophobicContact CG-CB 3.91Å; P13-L446 HydrophobicContact CG-CD2 4.08Å
14L84.2Confident78.1Confident35 Ų3568 Ų6818%0.18336%0.362CS..SBendtrans-108.7146.3172.1-72.6176.2000110.4I12 K147 L150 L151I12-L14 HydrophobicContact CG2-CB 4.09Å; I12-L14 HydrophobicContact CG2-CD1 3.98Å; I12-L14 HydrophobicContact CG2-CG 3.9Å; I12-L14 PolarHBondContact O-N 3.12Å; L14-K147 HydrophobicContact CB-CD 4.5Å; L14-K147 WeakPolarHBondContact O-CD 3.34Å; L14-K147 WeakPolarHBondContact O-CE 3.47Å; L14-K147 PolarHBondContact O-NZ 3.44Å; L14-L150 HydrophobicContact CD1-CD2 4.37Å; L14-L150 HydrophobicContact CD1-CG 4.42Å; L14-L151 HydrophobicContact CD1-CB 3.77Å; L14-L151 HydrophobicContact CD1-CD1 4.05Å; L14-L151 HydrophobicContact CD1-CG 4.41Å
15P82.6Confident80.5Confident82 Ų8264.8 Ų64.853%0.53234%0.342SS..  trans-63.7149.1170.628.2-33.4000110.2L17P15-L17 HydrophobicContact CB-CD2 4.28Å; P15-L17 HydrophobicContact CG-CD2 4.02Å; P15-L17 HydrophobicContact CG-CG 4.21Å; P15-L17 PolarHBondContact O-N 3.43Å
16K78.6Confident82.6Confident179 Ų17958.1 Ų58.178%0.77831%0.31SS*.  trans-76.3104.9170.7-168.9175.7-176176.20107.3
17L83.3Confident84.4Confident48 Ų4858.2 Ų58.225%0.25131%0.314SS..  trans-94.6148.5-179.8-63.7-178.4000110.8P15 Q21 A22 L150P15-L17 HydrophobicContact CB-CD2 4.28Å; P15-L17 HydrophobicContact CG-CD2 4.02Å; P15-L17 HydrophobicContact CG-CG 4.21Å; P15-L17 PolarHBondContact O-N 3.43Å; L17-Q21 HydrophobicContact CB-CB 4.16Å; L17-Q21 HydrophobicContact CD2-CB 4.48Å; L17-A22 HydrophobicContact CB-CB 4.27Å; L17-L150 HydrophobicContact CD1-CD2 3.8Å; L17-L150 HydrophobicContact CG-CD2 4.34Å
18G81.8Confident86.2Confident38 Ų3854.7 Ų54.739%0.39231%0.308SS..  trans-65.5157.5166.200000111.2V20 Q21 A22G18-V20 VanDerWaalsContact C-N 3.29Å; G18-V20 PolarHBondContact O-N 3.12Å; G18-Q21 PolarHBondContact O-N 2.84Å; G18-A22 WeakPolarHBondContact O-CB 3.37Å; G18-A22 PolarHBondContact O-N 3.18Å
19A81.9Confident87.4Confident49 Ų4955.5 Ų55.541%0.40531%0.314SS..Hα-helixtrans-55.5-42-176.700000112.9K23A19-K23 VanDerWaalsContact O-CG 3.28Å; A19-K23 WeakPolarHBondContact O-CG 3.46Å; A19-K23 PolarHBondContact O-N 2.86Å; A19-K23 VanDerWaalsContact O-N 3.07Å
20V87.5Confident88.4Confident113 Ų11354.5 Ų54.569%0.68531%0.308SS*.Hα-helixtrans-65.7-45.3176.9179.60000111.3G18 A22 K23 V24G18-V20 VanDerWaalsContact C-N 3.29Å; G18-V20 PolarHBondContact O-N 3.12Å; V20-A22 VanDerWaalsContact C-N 3.35Å; V20-A22 PolarHBondContact O-N 3.07Å; V20-K23 PolarHBondContact O-N 2.87Å; V20-V24 HydrophobicContact CG1-CG2 4.34Å; V20-V24 WeakPolarHBondContact O-CG2 3.4Å; V20-V24 PolarHBondContact O-N 3.2Å
21Q90.4Very high89.4Confident112 Ų11253.4 Ų53.452%0.52331%0.305SS..Hα-helixtrans-63-41179-69.1173.2-21.100111.9L17 G18 V24 T25L17-Q21 HydrophobicContact CB-CB 4.16Å; L17-Q21 HydrophobicContact CD2-CB 4.48Å; G18-Q21 PolarHBondContact O-N 2.84Å; Q21-V24 PolarHBondContact O-N 3.34Å; Q21-T25 WeakPolarHBondContact O-CB 3.26Å; Q21-T25 PolarHBondContact O-N 3.12Å; Q21-T25 PolarHBondContact O-OG1 3.35Å
22A91.1Very high90.2Very high0 Ų056.3 Ų56.30%032%0.322CS..Hα-helixtrans-59.9-48.1174.800000111.3L17 G18 V20 T25 V26 I123 A145 L150L17-A22 HydrophobicContact CB-CB 4.27Å; G18-A22 WeakPolarHBondContact O-CB 3.37Å; G18-A22 PolarHBondContact O-N 3.18Å; V20-A22 VanDerWaalsContact C-N 3.35Å; V20-A22 PolarHBondContact O-N 3.07Å; A22-T25 PolarHBondContact O-N 2.91Å; A22-V26 PolarHBondContact O-N 3.29Å; A22-I123 HydrophobicContact CB-CD1 4.34Å; A22-A145 HydrophobicContact CB-CB 4.1Å; A22-L150 HydrophobicContact CB-CD1 4.03Å
23K93.5Very high90.8Very high67 Ų6756.2 Ų56.229%0.29132%0.321SS..Hα-helixtrans-61.6-46.4177.1-70.3-176.7176.5-166.70112A19 V20 T25 V26 A27 V120 I123 D124A19-K23 VanDerWaalsContact O-CG 3.28Å; A19-K23 WeakPolarHBondContact O-CG 3.46Å; A19-K23 PolarHBondContact O-N 2.86Å; A19-K23 VanDerWaalsContact O-N 3.07Å; V20-K23 PolarHBondContact O-N 2.87Å; K23-T25 VanDerWaalsContact C-N 3.33Å; K23-T25 PolarHBondContact O-N 3.39Å; K23-V26 PolarHBondContact O-N 3.08Å; K23-A27 WeakPolarHBondContact O-CB 3.49Å; K23-A27 PolarHBondContact O-N 3.46Å; K23-V120 HydrophobicContact CB-CG1 3.84Å; K23-V120 HydrophobicContact CD-CG1 3.94Å; K23-V120 HydrophobicContact CG-CG1 3.77Å; K23-V120 WeakPolarHBondContact O-CG2 3.38Å; K23-I123 HydrophobicContact CG-CD1 3.96Å; K23-D124 WeakPolarHBondContact CE-OD2 3.36Å; K23-D124 IonicContact NZ-OD1 3.56Å; K23-D124 IonicContact NZ-OD2 3.72Å; K23-D124 PolarHBondContact NZ-OD2 3.37Å
24V95.6Very high91.5Very high82 Ų8254.7 Ų54.750%0.49731%0.311SS..Hα-helixtrans-61.2-42.3176.21720000111.2V20 Q21 V26 A27 V28V20-V24 HydrophobicContact CG1-CG2 4.34Å; V20-V24 WeakPolarHBondContact O-CG2 3.4Å; V20-V24 PolarHBondContact O-N 3.2Å; Q21-V24 PolarHBondContact O-N 3.34Å; V24-V26 PolarHBondContact O-N 3.16Å; V24-A27 PolarHBondContact O-N 3.18Å; V24-V28 HydrophobicContact CG1-CG2 4.3Å; V24-V28 WeakPolarHBondContact O-CG2 3.43Å; V24-V28 PolarHBondContact O-N 2.88Å
25T95.3Very high92.1Very high52 Ų5256.6 Ų56.632%0.31932%0.321SS..Hα-helixtrans-59.6-48.2178.7-580000111.3Q21 A22 K23 A27 V28 V29 I154Q21-T25 WeakPolarHBondContact O-CB 3.26Å; Q21-T25 PolarHBondContact O-N 3.12Å; Q21-T25 PolarHBondContact O-OG1 3.35Å; A22-T25 PolarHBondContact O-N 2.91Å; K23-T25 VanDerWaalsContact C-N 3.33Å; K23-T25 PolarHBondContact O-N 3.39Å; T25-A27 PolarHBondContact O-N 3.42Å; T25-V28 PolarHBondContact O-N 2.88Å; T25-V29 WeakPolarHBondContact O-CG2 3.37Å; T25-V29 PolarHBondContact O-N 2.94Å; T25-I154 HydrophobicContact CG2-CD1 4.45Å
26V96.9Very high92.6Very high0 Ų056.2 Ų56.20%031%0.314CS..Hα-helixtrans-64.4-41178.4173.30000111.7A22 K23 V24 V28 V29 A30 S119 I123 L150 A153 I154 A157A22-V26 PolarHBondContact O-N 3.29Å; K23-V26 PolarHBondContact O-N 3.08Å; V24-V26 PolarHBondContact O-N 3.16Å; V26-V28 PolarHBondContact O-N 3.5Å; V26-V29 PolarHBondContact O-N 3.43Å; V26-A30 WeakPolarHBondContact O-CB 3.21Å; V26-A30 PolarHBondContact O-N 3.19Å; V26-S119 WeakPolarHBondContact CG1-O 3.22Å; V26-I123 HydrophobicContact CB-CD1 4.16Å; V26-I123 HydrophobicContact CG2-CD1 3.7Å; V26-I123 HydrophobicContact CG2-CG1 4.13Å; V26-L150 HydrophobicContact CG2-CD1 3.76Å; V26-A153 HydrophobicContact CG1-CB 4.35Å; V26-A153 HydrophobicContact CG2-CB 4Å; V26-I154 HydrophobicContact CG2-CG1 3.87Å; V26-A157 HydrophobicContact CG1-CB 4.02Å
27A97.8Very high93.4Very high24 Ų2447.8 Ų47.820%0.19828%0.278CS..Hα-helixtrans-60.4-45.4175.700000111.8K23 V24 T25 A30 L31 V120K23-A27 WeakPolarHBondContact O-CB 3.49Å; K23-A27 PolarHBondContact O-N 3.46Å; V24-A27 PolarHBondContact O-N 3.18Å; T25-A27 PolarHBondContact O-N 3.42Å; A27-A30 PolarHBondContact O-N 2.91Å; A27-L31 VanDerWaalsContact O-CG 3.27Å; A27-L31 WeakPolarHBondContact O-CG 3.45Å; A27-L31 PolarHBondContact O-N 2.92Å; A27-V120 HydrophobicContact CB-CG2 3.79Å
28V97.8Very high94Very high72 Ų7250.6 Ų50.644%0.43629%0.286SS..Hα-helixtrans-63-43.4178.1170.80000111.2V24 T25 V26 A30 L31 L32V24-V28 HydrophobicContact CG1-CG2 4.3Å; V24-V28 WeakPolarHBondContact O-CG2 3.43Å; V24-V28 PolarHBondContact O-N 2.88Å; T25-V28 PolarHBondContact O-N 2.88Å; V26-V28 PolarHBondContact O-N 3.5Å; V28-A30 PolarHBondContact O-N 2.9Å; V28-L31 PolarHBondContact O-N 3.31Å; V28-L32 HydrophobicContact CG1-CD1 3.86Å; V28-L32 HydrophobicContact CG1-CG 4.25Å; V28-L32 WeakPolarHBondContact O-CB 3.42Å; V28-L32 VanDerWaalsContact O-CG 3.29Å; V28-L32 WeakPolarHBondContact O-CG 3.48Å; V28-L32 PolarHBondContact O-N 3.25Å
29V97.7Very high94.7Very high23 Ų2351.5 Ų51.514%0.13928%0.282CS..Hα-helixtrans-60.4-46.8176.1171.60000111.1T25 V26 L31 L32 C33 I154 A157 A158T25-V29 WeakPolarHBondContact O-CG2 3.37Å; T25-V29 PolarHBondContact O-N 2.94Å; V26-V29 PolarHBondContact O-N 3.43Å; V29-L31 VanDerWaalsContact C-N 3.33Å; V29-L31 PolarHBondContact O-N 2.89Å; V29-L32 PolarHBondContact O-N 2.86Å; V29-C33 PolarHBondContact O-N 3.3Å; V29-C33 VanDerWaalsContact O-N 3.09Å; V29-C33 PolarHBondContact O-SG 3.49Å; V29-I154 HydrophobicContact CG1-CG2 4.5Å; V29-A157 HydrophobicContact CG1-CB 4.21Å; V29-A158 HydrophobicContact CG1-CB 3.97Å
30A97.9Very high95.4Very high0 Ų049.3 Ų49.30%026%0.264CS..Hα-helixtrans-58.5-44.6177.100000111.6V26 A27 V28 C33 F34 A116 A157V26-A30 WeakPolarHBondContact O-CB 3.21Å; V26-A30 PolarHBondContact O-N 3.19Å; A27-A30 PolarHBondContact O-N 2.91Å; V28-A30 PolarHBondContact O-N 2.9Å; A30-C33 PolarHBondContact O-N 2.96Å; A30-F34 VanDerWaalsContact O-CD2 3.32Å; A30-F34 WeakPolarHBondContact O-CD2 3.29Å; A30-A116 HydrophobicContact CB-CB 4.05Å; A30-A157 HydrophobicContact CB-CB 4.05Å
31L97.1Very high95.8Very high68 Ų6849.5 Ų49.536%0.35626%0.258SS..Hα-helixtrans-62.6-49.1176.9-68.7173.4000111.5A27 V28 V29 C33 F34 I35 I112 A116A27-L31 VanDerWaalsContact O-CG 3.27Å; A27-L31 WeakPolarHBondContact O-CG 3.45Å; A27-L31 PolarHBondContact O-N 2.92Å; V28-L31 PolarHBondContact O-N 3.31Å; V29-L31 VanDerWaalsContact C-N 3.33Å; V29-L31 PolarHBondContact O-N 2.89Å; L31-C33 PolarHBondContact O-N 3.04Å; L31-F34 PolarHBondContact O-N 3.37Å; L31-I35 VanDerWaalsContact O-CB 3.24Å; L31-I35 WeakPolarHBondContact O-CB 3.35Å; L31-I35 PolarHBondContact O-N 3.44Å; L31-I112 HydrophobicContact CD2-CG2 3.64Å; L31-A116 HydrophobicContact CD2-CB 4.38Å
32L96.2Very high96.1Very high104 Ų10445.5 Ų45.555%0.54524%0.238SC..Hα-helixtrans-58.4-33.1-179.9-72.8172.3000113V28 V29V28-L32 HydrophobicContact CG1-CD1 3.86Å; V28-L32 HydrophobicContact CG1-CG 4.25Å; V28-L32 WeakPolarHBondContact O-CB 3.42Å; V28-L32 VanDerWaalsContact O-CG 3.29Å; V28-L32 WeakPolarHBondContact O-CG 3.48Å; V28-L32 PolarHBondContact O-N 3.25Å; V29-L32 PolarHBondContact O-N 2.86Å
33C97.5Very high96.3Very high0 Ų045.5 Ų45.50%024%0.238CC..Hα-helixtrans-67.8-35.6179.7-71.20000113.5V29 A30 L31 C457 A458V29-C33 PolarHBondContact O-N 3.3Å; V29-C33 VanDerWaalsContact O-N 3.09Å; V29-C33 PolarHBondContact O-SG 3.49Å; A30-C33 PolarHBondContact O-N 2.96Å; L31-C33 PolarHBondContact O-N 3.04Å; C33-C457 HydrophobicContact CB-CB 3.64Å; C33-C457 CarbonylContact O-C 3.56Å; C33-C457 WeakPolarHBondContact O-CB 3.24Å; C33-A458 WeakPolarHBondContact O-CA 3.42Å; C33-A458 PolarHBondContact O-N 2.87Å
34F97.4Very high96.2Very high0 Ų043.5 Ų43.50%023%0.23CC..Hα-helixtrans-123-4.9-166.9-58.7-72.2000114.3A30 L31 N36 S37 I112 H115 H162 T163 V166 C457 S461A30-F34 VanDerWaalsContact O-CD2 3.32Å; A30-F34 WeakPolarHBondContact O-CD2 3.29Å; L31-F34 PolarHBondContact O-N 3.37Å; F34-N36 PolarHBondContact O-N 3.23Å; F34-S37 PolarHBondContact O-N 3.07Å; F34-S37 VanDerWaalsContact O-N 3.09Å; F34-S37 PolarHBondContact O-OG 2.89Å; F34-I112 HydrophobicContact CB-CG1 4.15Å; F34-I112 WeakPolarHBondContact O-CD1 3.45Å; F34-H115 AromaticContact CD2-CD2 3.59Å; F34-H115 AromaticContact CE2-CD2 3.51Å; F34-H115 AromaticContact CE2-NE2 3.45Å; F34-H115 WeakPolarHBondContact CE2-NE2 3.34Å; F34-H162 HydrophobicContact CZ-CB 3.95Å; F34-T163 HydrophobicContact CE1-CG2 4.34Å; F34-V166 HydrophobicContact CB-CG1 3.66Å; F34-V166 HydrophobicContact CD1-CB 3.85Å; F34-V166 HydrophobicContact CD1-CG1 3.88Å; F34-V166 HydrophobicContact CD1-CG2 4.4Å; F34-V166 HydrophobicContact CD2-CB 4.4Å; F34-V166 HydrophobicContact CD2-CG1 3.98Å; F34-V166 HydrophobicContact CD2-CG2 4.34Å; F34-V166 HydrophobicContact CE1-CB 4.19Å; F34-V166 HydrophobicContact CE1-CG2 4.37Å; F34-V166 HydrophobicContact CE2-CG2 4.28Å; F34-V166 HydrophobicContact CG-CB 4.01Å; F34-V166 HydrophobicContact CG-CG1 3.55Å; F34-V166 HydrophobicContact CG-CG2 4.44Å; F34-V166 HydrophobicContact CZ-CG2 4.32Å; F34-C457 HydrophobicContact CE1-CB 4.05Å; F34-C457 HydrophobicContact CZ-CB 4.13Å; F34-S461 WeakPolarHBondContact CD1-OG 3.45Å
35I95.7Very high96.1Very high75 Ų7541 Ų4139%0.38521%0.214SC..G310 helixtrans-56.8-30.6-178-166.263.3000112.4L31 S37 Y38L31-I35 VanDerWaalsContact O-CB 3.24Å; L31-I35 WeakPolarHBondContact O-CB 3.35Å; L31-I35 PolarHBondContact O-N 3.44Å; I35-S37 PolarHBondContact O-N 3.27Å; I35-S37 VanDerWaalsContact O-N 3.09Å; I35-Y38 WeakPolarHBondContact O-CB 3.38Å; I35-Y38 WeakPolarHBondContact O-CD1 3.49Å; I35-Y38 PolarHBondContact O-N 3.45Å; I35-Y38 VanDerWaalsContact O-N 3.13Å
36N93.9Very high96.2Very high75 Ų7538.6 Ų38.640%0.40120%0.199SC..G310 helixtrans-65.9-10.5-179.1-71.4-6.6000114.8F34 R465F34-N36 PolarHBondContact O-N 3.23Å; N36-R465 VanDerWaalsContact O-CD 3.24Å; N36-R465 WeakPolarHBondContact O-CD 3.5Å
37S95.4Very high96Very high2 Ų240.1 Ų40.11%0.01421%0.21CC..G310 helixtrans-101.97.6175.362.20000113.9F34 I35 D39 G40F34-S37 PolarHBondContact O-N 3.07Å; F34-S37 VanDerWaalsContact O-N 3.09Å; F34-S37 PolarHBondContact O-OG 2.89Å; I35-S37 PolarHBondContact O-N 3.27Å; I35-S37 VanDerWaalsContact O-N 3.09Å; S37-D39 PolarHBondContact O-N 3.28Å; S37-G40 PolarHBondContact O-N 3.34Å
38Y96.6Very high95.8Very high106 Ų10643.9 Ų43.942%0.41622%0.223SC..THydrogen-bonded Turntrans-62.6-27.5-175.784.1-72.7000114.3I35 V105I35-Y38 WeakPolarHBondContact O-CB 3.38Å; I35-Y38 WeakPolarHBondContact O-CD1 3.49Å; I35-Y38 PolarHBondContact O-N 3.45Å; I35-Y38 VanDerWaalsContact O-N 3.13Å; Y38-V105 HydrophobicContact CD2-CG1 4.27Å; Y38-V105 WeakPolarHBondContact O-CA 3.05Å
39D95.8Very high95.7Very high57 Ų5740.4 Ų40.431%0.30520%0.202SC..THydrogen-bonded Turntrans-110.120.9-17769.8-14.1000113S37 R465S37-D39 PolarHBondContact O-N 3.28Å; D39-R465 IonicContact OD1-CZ 3.67Å; D39-R465 VanDerWaalsContact OD1-CZ 3.29Å; D39-R465 IonicContact OD1-NE 3.23Å; D39-R465 PolarHBondContact OD1-NE 2.91Å; D39-R465 IonicContact OD1-NH2 3.01Å; D39-R465 PolarHBondContact OD1-NH2 2.86Å; D39-R465 IonicContact OD2-CZ 3.77Å; D39-R465 IonicContact OD2-NH2 3.34Å; D39-R465 PolarHBondContact OD2-NH2 3.4Å
40G95.9Very high95.6Very high3 Ų339.4 Ų39.43%0.03120%0.196CC..  trans-63.8159.617500000113.5S37 P104 H108 R465S37-G40 PolarHBondContact O-N 3.34Å; G40-P104 WeakPolarHBondContact O-CB 3.49Å; G40-H108 PolarHBondContact O-CD2 3.5Å; G40-H108 PolarHBondContact O-NE2 2.99Å; G40-R465 WeakPolarHBondContact CA-O 3.31Å
41E96.9Very high95.5Very high118 Ų11841.8 Ų41.855%0.55121%0.21SC*.  trans-81.4167.7169.9-62.5177.6159.200110.8V43 H108 R465E41-V43 HydrophobicContact CB-CG1 4.29Å; E41-V43 PolarHBondContact O-N 3.01Å; E41-H108 PolarHBondContact O-NE2 2.86Å; E41-R465 PolarHBondContact N-O 3.07Å
42F96.7Very high95.4Very high27 Ų2742.9 Ų42.912%0.11822%0.216CC..  trans-70.5115.5164.3-64-58.9000108.7D46 I50 V51 L102 P104 F107 V169F42-D46 HydrophobicContact CB-CB 3.85Å; F42-D46 HydrophobicContact CD1-CB 4.09Å; F42-D46 HydrophobicContact CG-CB 4.43Å; F42-I50 HydrophobicContact CD1-CD1 4.02Å; F42-I50 HydrophobicContact CD1-CG2 4.4Å; F42-I50 HydrophobicContact CE1-CD1 3.98Å; F42-I50 HydrophobicContact CE1-CG2 3.92Å; F42-I50 HydrophobicContact CZ-CG2 4.1Å; F42-V51 HydrophobicContact CB-CG2 3.87Å; F42-V51 HydrophobicContact CD2-CG2 3.58Å; F42-V51 HydrophobicContact CE2-CG2 4.34Å; F42-V51 HydrophobicContact CG-CG2 3.85Å; F42-L102 HydrophobicContact CE2-CB 4.05Å; F42-L102 HydrophobicContact CE2-CD2 4.38Å; F42-L102 HydrophobicContact CZ-CD2 4.46Å; F42-P104 HydrophobicContact CD2-CG 3.85Å; F42-P104 HydrophobicContact CE1-CB 4.33Å; F42-P104 HydrophobicContact CE2-CB 4.26Å; F42-P104 HydrophobicContact CE2-CG 3.63Å; F42-P104 HydrophobicContact CG-CG 4.4Å; F42-P104 HydrophobicContact CZ-CB 4.15Å; F42-P104 HydrophobicContact CZ-CG 4.01Å; F42-F107 HydrophobicContact CE1-CB 4.41Å; F42-F107 HydrophobicContact CE1-CD2 4.21Å; F42-F107 HydrophobicContact CE1-CG 4.19Å; F42-F107 AromaticContact CZ-CD2 3.99Å; F42-F107 HydrophobicContact CZ-CD2 3.99Å; F42-F107 HydrophobicContact CZ-CE2 4.15Å; F42-F107 HydrophobicContact CZ-CG 4.43Å; F42-V169 HydrophobicContact CD1-CG2 4.19Å; F42-V169 HydrophobicContact CE1-CG2 4.25Å
43V94.6Very high95.4Very high0 Ų038 Ų380%019%0.191CC..  trans-121.3147.9-174.5-60.20000111.9E41 D45 D46 W464 E467 L470E41-V43 HydrophobicContact CB-CG1 4.29Å; E41-V43 PolarHBondContact O-N 3.01Å; V43-D45 PolarHBondContact O-N 3.29Å; V43-D45 VanDerWaalsContact O-N 3.17Å; V43-D46 PolarHBondContact N-OD2 3.44Å; V43-D46 VanDerWaalsContact O-CB 3.32Å; V43-D46 WeakPolarHBondContact O-CB 3.35Å; V43-D46 PolarHBondContact O-N 2.88Å; V43-W464 HydrophobicContact CG2-CE3 3.79Å; V43-W464 HydrophobicContact CG2-CZ3 4.28Å; V43-W464 WeakPolarHBondContact CG2-O 3.38Å; V43-E467 HydrophobicContact CB-CG 3.85Å; V43-E467 HydrophobicContact CG1-CG 3.93Å; V43-E467 VanDerWaalsContact CG1-N 3.33Å; V43-L470 HydrophobicContact CB-CD2 4.42Å; V43-L470 HydrophobicContact CG2-CD2 4.08Å
44F92.8Very high95.2Very high26 Ų2644.9 Ų44.911%0.11422%0.221CC..THydrogen-bonded Turntrans56.3-118.5171.4-172-121.6000112.2D46 S47 F336 D337 E467 L470 F471F44-D46 PolarHBondContact O-N 3.29Å; F44-S47 WeakPolarHBondContact O-CB 3.28Å; F44-S47 PolarHBondContact O-N 3.38Å; F44-F336 HydrophobicContact CD1-CD2 4.01Å; F44-F336 AromaticContact CD2-CD2 3.8Å; F44-F336 HydrophobicContact CD2-CD2 3.8Å; F44-F336 AromaticContact CD2-CE2 3.78Å; F44-F336 HydrophobicContact CD2-CE2 3.78Å; F44-F336 AromaticContact CE1-CD2 3.76Å; F44-F336 HydrophobicContact CE1-CD2 3.76Å; F44-F336 HydrophobicContact CE1-CE2 4.42Å; F44-F336 AromaticContact CE2-CD2 3.54Å; F44-F336 HydrophobicContact CE2-CD2 3.54Å; F44-F336 AromaticContact CE2-CE2 3.37Å; F44-F336 HydrophobicContact CE2-CE2 3.37Å; F44-F336 HydrophobicContact CG-CD2 4.03Å; F44-F336 HydrophobicContact CG-CE2 4.46Å; F44-F336 AromaticContact CZ-CD2 3.51Å; F44-F336 HydrophobicContact CZ-CD2 3.51Å; F44-F336 AromaticContact CZ-CE2 3.74Å; F44-F336 HydrophobicContact CZ-CE2 3.74Å; F44-D337 HydrophobicContact CZ-CB 4.39Å; F44-E467 PolarHBondContact N-OE1 2.91Å; F44-L470 HydrophobicContact CB-CD2 3.96Å; F44-F471 HydrophobicContact CB-CE1 4.17Å; F44-F471 HydrophobicContact CB-CZ 4.31Å; F44-F471 AromaticContact CD2-CE1 3.7Å; F44-F471 HydrophobicContact CD2-CE1 3.7Å; F44-F471 AromaticContact CD2-CZ 3.99Å; F44-F471 HydrophobicContact CD2-CZ 3.99Å; F44-F471 HydrophobicContact CG-CE1 4.25Å
45D93.3Very high95.1Very high30 Ų3045 Ų4516%0.1622%0.221CC..Hα-helixtrans-63.6-20.5-178.9-79.7-8.2000112.9V43 S47 E48 A49 W71 V170 R411V43-D45 PolarHBondContact O-N 3.29Å; V43-D45 VanDerWaalsContact O-N 3.17Å; D45-S47 VanDerWaalsContact C-N 3.26Å; D45-S47 PolarHBondContact O-N 2.71Å; D45-E48 PolarHBondContact O-N 2.84Å; D45-A49 WeakPolarHBondContact O-CB 3.38Å; D45-A49 PolarHBondContact O-N 2.99Å; D45-W71 HydrophobicContact CB-CH2 4Å; D45-W71 HydrophobicContact CB-CZ3 4.09Å; D45-V170 HydrophobicContact CB-CG1 4.14Å; D45-V170 HydrophobicContact CB-CG2 3.82Å; D45-R411 IonicContact OD2-NH1 3.97Å; D45-R411 PolarHBondContact OD2-NH1 3.48Å
46D96.1Very high95.1Very high0 Ų041.5 Ų41.50%020%0.204CC..Hα-helixtrans-63.7-33177.8-64.6-21.5000111.9F42 V43 F44 E48 I50 V51 V169 V170F42-D46 HydrophobicContact CB-CB 3.85Å; F42-D46 HydrophobicContact CD1-CB 4.09Å; F42-D46 HydrophobicContact CG-CB 4.43Å; V43-D46 PolarHBondContact N-OD2 3.44Å; V43-D46 VanDerWaalsContact O-CB 3.32Å; V43-D46 WeakPolarHBondContact O-CB 3.35Å; V43-D46 PolarHBondContact O-N 2.88Å; F44-D46 PolarHBondContact O-N 3.29Å; D46-E48 VanDerWaalsContact C-N 3.31Å; D46-E48 PolarHBondContact O-N 3.47Å; D46-I50 HydrophobicContact CB-CD1 4.11Å; D46-I50 WeakPolarHBondContact O-CA 3.01Å; D46-I50 VanDerWaalsContact O-CB 3.23Å; D46-I50 WeakPolarHBondContact O-CB 3.29Å; D46-I50 PolarHBondContact O-N 3.28Å; D46-V51 PolarHBondContact O-N 2.68Å; D46-V169 WeakPolarHBondContact OD1-CA 3.28Å; D46-V169 WeakPolarHBondContact OD1-CB 3.24Å; D46-V169 PolarHBondContact OD1-N 3.33Å; D46-V169 VanDerWaalsContact OD1-N 3.11Å; D46-V169 PolarHBondContact OD2-N 3.4Å; D46-V170 WeakPolarHBondContact OD1-CG1 3.32Å; D46-V170 PolarHBondContact OD1-N 3.07Å
47S93.1Very high95Very high33 Ų3342.4 Ų42.423%0.23120%0.204CC..Iπ-helixtrans-58.4-43.3177.6-66.30000111.6F44 D45 V51 N52F44-S47 WeakPolarHBondContact O-CB 3.28Å; F44-S47 PolarHBondContact O-N 3.38Å; D45-S47 VanDerWaalsContact C-N 3.26Å; D45-S47 PolarHBondContact O-N 2.71Å; S47-V51 WeakPolarHBondContact O-CB 3.5Å; S47-V51 PolarHBondContact O-N 3.12Å; S47-N52 WeakPolarHBondContact O-CB 3.33Å; S47-N52 PolarHBondContact O-N 3.45Å
48E92.9Very high94.7Very high102 Ų10245.7 Ų45.748%0.47723%0.225SC..Iπ-helixtrans-82.4-47179.8-67.9-54.2124.900112.3D45 D46 I50 N52 N53 W71D45-E48 PolarHBondContact O-N 2.84Å; D46-E48 VanDerWaalsContact C-N 3.31Å; D46-E48 PolarHBondContact O-N 3.47Å; E48-I50 VanDerWaalsContact C-N 3.29Å; E48-I50 PolarHBondContact O-N 3.5Å; E48-N52 PolarHBondContact OE1-ND2 2.88Å; E48-N53 PolarHBondContact O-N 2.9Å; E48-W71 HydrophobicContact CB-CE3 3.81Å; E48-W71 HydrophobicContact CB-CZ3 4.07Å
49A95.4Very high94.5Very high0 Ų046.8 Ų46.80%024%0.243CC..Iπ-helixtrans-72.3-21.8-174.100000113.9D45 N53 F70 W71 V170D45-A49 WeakPolarHBondContact O-CB 3.38Å; D45-A49 PolarHBondContact O-N 2.99Å; A49-N53 WeakPolarHBondContact O-CB 3.37Å; A49-N53 PolarHBondContact O-ND2 2.86Å; A49-F70 HydrophobicContact CB-CD1 4.26Å; A49-F70 HydrophobicContact CB-CE1 3.66Å; A49-F70 HydrophobicContact CB-CZ 4.07Å; A49-W71 HydrophobicContact CB-CE3 3.76Å; A49-W71 HydrophobicContact CB-CZ3 3.79Å; A49-V170 HydrophobicContact CB-CG1 3.32Å
50I96.3Very high94.4Very high1 Ų145 Ų451%0.00523%0.234CC..Iπ-helixtrans-123.6-61.2-172.7-49.9176.8000110.8F42 D46 E48 N53 L56 L102 F107 V169F42-I50 HydrophobicContact CD1-CD1 4.02Å; F42-I50 HydrophobicContact CD1-CG2 4.4Å; F42-I50 HydrophobicContact CE1-CD1 3.98Å; F42-I50 HydrophobicContact CE1-CG2 3.92Å; F42-I50 HydrophobicContact CZ-CG2 4.1Å; D46-I50 HydrophobicContact CB-CD1 4.11Å; D46-I50 WeakPolarHBondContact O-CA 3.01Å; D46-I50 VanDerWaalsContact O-CB 3.23Å; D46-I50 WeakPolarHBondContact O-CB 3.29Å; D46-I50 PolarHBondContact O-N 3.28Å; E48-I50 VanDerWaalsContact C-N 3.29Å; E48-I50 PolarHBondContact O-N 3.5Å; I50-N53 PolarHBondContact O-N 3Å; I50-L56 HydrophobicContact CB-CD2 4.19Å; I50-L56 HydrophobicContact CG2-CD2 3.54Å; I50-L102 HydrophobicContact CG2-CD2 3.8Å; I50-F107 HydrophobicContact CG2-CE1 4.14Å; I50-F107 HydrophobicContact CG2-CZ 4.37Å; I50-V169 HydrophobicContact CD1-CB 3.48Å; I50-V169 VanDerWaalsContact CD1-CB 3.48Å; I50-V169 HydrophobicContact CD1-CG1 3.21Å; I50-V169 HydrophobicContact CD1-CG2 4.37Å
51V96Very high94.4Very high51 Ų5148.3 Ų48.331%0.30926%0.255SS..Iπ-helixtrans-67.7-47.2-171.4-178.70000111.3F42 D46 S47 L102F42-V51 HydrophobicContact CB-CG2 3.87Å; F42-V51 HydrophobicContact CD2-CG2 3.58Å; F42-V51 HydrophobicContact CE2-CG2 4.34Å; F42-V51 HydrophobicContact CG-CG2 3.85Å; D46-V51 PolarHBondContact O-N 2.68Å; S47-V51 WeakPolarHBondContact O-CB 3.5Å; S47-V51 PolarHBondContact O-N 3.12Å; V51-L102 HydrophobicContact CB-CD1 4.45Å; V51-L102 HydrophobicContact CG1-CD1 4.18Å
52N94.9Very high94.3Very high90 Ų9047 Ų4748%0.48125%0.251SS..SBendtrans-87.1-10.7-179-67.2-27.2000113.3S47 E48 K54S47-N52 WeakPolarHBondContact O-CB 3.33Å; S47-N52 PolarHBondContact O-N 3.45Å; E48-N52 PolarHBondContact OE1-ND2 2.88Å; N52-K54 PolarHBondContact O-N 3.1Å
53N95.6Very high94.2Very high1 Ų148.7 Ų48.71%0.00527%0.266CS..  trans-74.2113.9-178.7-171.1-17.4000111.8E48 A49 I50 D55 L56 F70 G72E48-N53 PolarHBondContact O-N 2.9Å; A49-N53 WeakPolarHBondContact O-CB 3.37Å; A49-N53 PolarHBondContact O-ND2 2.86Å; I50-N53 PolarHBondContact O-N 3Å; N53-D55 VanDerWaalsContact C-N 3.26Å; N53-D55 PolarHBondContact O-N 3.4Å; N53-D55 WeakPolarHBondContact OD1-CB 3.49Å; N53-D55 PolarHBondContact OD1-N 2.59Å; N53-L56 HydrophobicContact CB-CD1 3.97Å; N53-F70 PolarHBondContact ND2-O 3.5Å; N53-G72 WeakPolarHBondContact OD1-CA 3.19Å
54K94.3Very high94.2Very high145 Ų14550.9 Ų50.963%0.6328%0.278SS*.G310 helixtrans-70.7-21.9-177.6-62.2178.1-174.3172.70113N52 L56 K57 T60N52-K54 PolarHBondContact O-N 3.1Å; K54-L56 PolarHBondContact O-N 3.22Å; K54-K57 WeakPolarHBondContact O-CB 3.31Å; K54-K57 PolarHBondContact O-N 3.13Å; K54-K57 VanDerWaalsContact O-N 3.14Å; K54-T60 VanDerWaalsContact O-CB 3.31Å; K54-T60 WeakPolarHBondContact O-CB 3.47Å; K54-T60 PolarHBondContact O-OG1 2.88Å
55D95.6Very high94.3Very high3 Ų349.8 Ų49.82%0.01627%0.273CS..G310 helixtrans-70.5-18.6-176-70.1-26.4000113.2N53 K57 I65 N68 G72 V89 R93N53-D55 VanDerWaalsContact C-N 3.26Å; N53-D55 PolarHBondContact O-N 3.4Å; N53-D55 WeakPolarHBondContact OD1-CB 3.49Å; N53-D55 PolarHBondContact OD1-N 2.59Å; D55-K57 VanDerWaalsContact C-N 3.3Å; D55-I65 HydrophobicContact CB-CG1 4.26Å; D55-N68 VanDerWaalsContact CG-ND2 3.27Å; D55-N68 PolarHBondContact OD1-ND2 3.33Å; D55-N68 VanDerWaalsContact OD2-CB 3.24Å; D55-N68 WeakPolarHBondContact OD2-CB 3.27Å; D55-N68 PolarHBondContact OD2-ND2 2.73Å; D55-G72 WeakPolarHBondContact OD2-CA 3.13Å; D55-V89 HydrophobicContact CB-CG1 4.14Å; D55-R93 WeakPolarHBondContact O-CD 3.38Å; D55-R93 PolarHBondContact O-NH1 3Å
56L95.1Very high94.4Very high2 Ų254 Ų541%0.0129%0.287CS..G310 helixtrans-75.3-20.9174.9-80.461.5000112.2I50 N53 K54 V89 F92I50-L56 HydrophobicContact CB-CD2 4.19Å; I50-L56 HydrophobicContact CG2-CD2 3.54Å; N53-L56 HydrophobicContact CB-CD1 3.97Å; K54-L56 PolarHBondContact O-N 3.22Å; L56-V89 HydrophobicContact CD1-CG1 4.02Å; L56-F92 HydrophobicContact CD1-CB 4.16Å; L56-F92 HydrophobicContact CD2-CB 3.83Å; L56-F92 HydrophobicContact CG-CB 3.95Å
57K92.6Very high94.3Very high94 Ų9461.9 Ų61.941%0.40932%0.317SS..SBendtrans-76.5140.1-175.2-57.9-174-179.1-175.90111K54 D55 V59 T60K54-K57 WeakPolarHBondContact O-CB 3.31Å; K54-K57 PolarHBondContact O-N 3.13Å; K54-K57 VanDerWaalsContact O-N 3.14Å; D55-K57 VanDerWaalsContact C-N 3.3Å; K57-V59 HydrophobicContact CB-CG2 3.89Å; K57-V59 PolarHBondContact O-N 3.32Å; K57-T60 PolarHBondContact O-N 3.43Å
58P89.3Confident94.3Very high71 Ų7161.1 Ų61.146%0.46131%0.31SS..THydrogen-bonded Turntrans-60.9-31.2-179.1-22.432.3000113.3T60 Y96 L97P58-T60 PolarHBondContact O-N 2.87Å; P58-Y96 VanDerWaalsContact CD-CE1 3.48Å; P58-Y96 HydrophobicContact CG-CD1 4.42Å; P58-Y96 HydrophobicContact CG-CE1 3.79Å; P58-L97 HydrophobicContact CB-CD2 4.3Å; P58-L97 HydrophobicContact CG-CD2 3.85Å
59V92.4Very high94.4Very high129 Ų12956.3 Ų56.378%0.78229%0.288SS*.THydrogen-bonded Turntrans-65.1-21.6178.1-62.40000113.4K57K57-V59 HydrophobicContact CB-CG2 3.89Å; K57-V59 PolarHBondContact O-N 3.32Å
60T93.4Very high94.3Very high19 Ų1956.4 Ų56.412%0.11729%0.288CS..SBendtrans-87.1129.1-179-53.30000109.4K54 K57 P58 N64 R93K54-T60 VanDerWaalsContact O-CB 3.31Å; K54-T60 WeakPolarHBondContact O-CB 3.47Å; K54-T60 PolarHBondContact O-OG1 2.88Å; K57-T60 PolarHBondContact O-N 3.43Å; P58-T60 PolarHBondContact O-N 2.87Å; T60-N64 HydrophobicContact CG2-CB 4.22Å; T60-N64 VanDerWaalsContact CG2-ND2 3.32Å; T60-N64 WeakPolarHBondContact CG2-ND2 3.34Å; T60-R93 PolarHBondContact O-NH1 3.27Å; T60-R93 PolarHBondContact O-NH2 3.33Å
61P95.3Very high94.2Very high72 Ų7259 Ų5947%0.46830%0.298SS..  trans-56.3139.9179.8-26.935000113.2S63 N64P61-S63 PolarHBondContact O-N 3.47Å; P61-N64 WeakPolarHBondContact O-CB 3.35Å; P61-N64 PolarHBondContact O-N 2.83Å; P61-N64 VanDerWaalsContact O-N 3.14Å
62L94.3Very high94.1Very high90 Ų9057.5 Ų57.547%0.47129%0.292SS..G310 helixtrans-62.7-27.8-179.4-168.269.8000112.7N64 I65 L90L62-N64 PolarHBondContact O-N 3.34Å; L62-I65 HydrophobicContact CD1-CD1 3.69Å; L62-I65 PolarHBondContact O-N 3.34Å; L62-L90 HydrophobicContact CD1-CD1 3.84Å
63S94.9Very high93.9Very high63 Ų6355.2 Ų55.244%0.44128%0.284SS..G310 helixtrans-62.7-22.4177.153.50000113.6P61 I65 W66P61-S63 PolarHBondContact O-N 3.47Å; S63-I65 VanDerWaalsContact C-N 3.26Å; S63-I65 PolarHBondContact O-N 2.96Å; S63-W66 PolarHBondContact O-N 2.96Å
64N94.6Very high93.7Very high46 Ų4659.1 Ų59.125%0.24630%0.304CS..G310 helixtrans-64.5-30.7178.7-74.96.4000112.7T60 P61 L62 W66 R67 N68T60-N64 HydrophobicContact CG2-CB 4.22Å; T60-N64 VanDerWaalsContact CG2-ND2 3.32Å; T60-N64 WeakPolarHBondContact CG2-ND2 3.34Å; P61-N64 WeakPolarHBondContact O-CB 3.35Å; P61-N64 PolarHBondContact O-N 2.83Å; P61-N64 VanDerWaalsContact O-N 3.14Å; L62-N64 PolarHBondContact O-N 3.34Å; N64-W66 PolarHBondContact O-N 3.19Å; N64-W66 VanDerWaalsContact O-N 3.08Å; N64-R67 PolarHBondContact O-N 3.31Å; N64-N68 WeakPolarHBondContact O-CB 3.19Å; N64-N68 PolarHBondContact O-N 2.91Å
65I95.4Very high93.5Very high4 Ų452.5 Ų52.52%0.02128%0.276CS..G310 helixtrans-56.3-30.5177.6-64.1-180000111.4D55 L62 S63 P86 V89 L90D55-I65 HydrophobicContact CB-CG1 4.26Å; L62-I65 HydrophobicContact CD1-CD1 3.69Å; L62-I65 PolarHBondContact O-N 3.34Å; S63-I65 VanDerWaalsContact C-N 3.26Å; S63-I65 PolarHBondContact O-N 2.96Å; I65-P86 HydrophobicContact CG2-CB 3.7Å; I65-P86 WeakPolarHBondContact CG2-O 3.19Å; I65-P86 WeakPolarHBondContact O-CB 3.38Å; I65-V89 HydrophobicContact CD1-CG1 4.42Å; I65-V89 HydrophobicContact CG1-CG1 4.22Å; I65-V89 HydrophobicContact CG2-CB 4.2Å; I65-V89 HydrophobicContact CG2-CG1 4.35Å; I65-L90 HydrophobicContact CD1-CB 4.41Å; I65-L90 HydrophobicContact CD1-CD1 4.16Å
66W95.2Very high93Very high117 Ų11757.4 Ų57.444%0.44331%0.31SS..G310 helixtrans-85.6-9.1179.3-58.897.7000114S63 N64 P86 L87 L219S63-W66 PolarHBondContact O-N 2.96Å; N64-W66 PolarHBondContact O-N 3.19Å; N64-W66 VanDerWaalsContact O-N 3.08Å; W66-P86 HydrophobicContact CD2-CB 4.33Å; W66-P86 HydrophobicContact CE3-CB 3.93Å; W66-P86 HydrophobicContact CE3-CG 3.93Å; W66-P86 HydrophobicContact CZ3-CB 4.09Å; W66-P86 HydrophobicContact CZ3-CG 3.81Å; W66-L87 HydrophobicContact CH2-CD2 4.33Å; W66-L219 HydrophobicContact CZ3-CD1 4.29Å; W66-L219 HydrophobicContact CZ3-CD2 4.4Å
67R93.7Very high92.5Very high167 Ų16759.5 Ų59.563%0.6333%0.325SS*.THydrogen-bonded Turntrans-112.7-17.9-178.6-63.2-177.4179.7-175.5-0.6113N64 L75N64-R67 PolarHBondContact O-N 3.31Å; R67-L75 WeakPolarHBondContact O-CB 3.43Å; R67-L75 VanDerWaalsContact O-CG 3.28Å; R67-L75 WeakPolarHBondContact O-CG 3.39Å; R67-L75 PolarHBondContact O-N 2.88Å
68N94.3Very high91.8Very high16 Ų1662.9 Ų62.99%0.08635%0.348CS..BIsolated β-bridgetrans-100.1159.2-179.1-66.4-10.5000111.3D55 N64 S73 N74D55-N68 VanDerWaalsContact CG-ND2 3.27Å; D55-N68 PolarHBondContact OD1-ND2 3.33Å; D55-N68 VanDerWaalsContact OD2-CB 3.24Å; D55-N68 WeakPolarHBondContact OD2-CB 3.27Å; D55-N68 PolarHBondContact OD2-ND2 2.73Å; N64-N68 WeakPolarHBondContact O-CB 3.19Å; N64-N68 PolarHBondContact O-N 2.91Å; N68-S73 CarbonylContact C-O 3.15Å; N68-S73 WeakPolarHBondContact CA-O 3.42Å; N68-S73 WeakPolarHBondContact CB-O 3.46Å; N68-N74 VanDerWaalsContact OD1-CA 3.32Å; N68-N74 WeakPolarHBondContact OD1-CA 3.27Å
69D93.5Very high91Very high2 Ų263.5 Ų63.51%0.01135%0.354CS..  trans-78.2177.416867.819000111.5W71 G72 S73 L75 S80 H81D69-W71 PolarHBondContact O-N 3.4Å; D69-W71 WeakPolarHBondContact OD1-CA 3.47Å; D69-W71 PolarHBondContact OD1-N 2.9Å; D69-G72 PolarHBondContact O-N 2.95Å; D69-G72 PolarHBondContact OD1-N 3.34Å; D69-S73 PolarHBondContact N-O 3.28Å; D69-S73 PolarHBondContact OD1-N 3.45Å; D69-L75 HydrophobicContact CB-CD2 3.91Å; D69-S80 WeakPolarHBondContact OD2-CA 3.46Å; D69-S80 WeakPolarHBondContact OD2-CB 3.3Å; D69-S80 PolarHBondContact OD2-OG 3.07Å; D69-H81 PolarHBondContact OD2-N 3.42Å
70F94.8Very high90.6Very high2 Ų257.9 Ų57.91%0.00932%0.32CS..THydrogen-bonded Turntrans-55.3-24.3-179.3179.6-109.8000113.9A49 N53 S83 R85 T88 V89 F92 V170A49-F70 HydrophobicContact CB-CD1 4.26Å; A49-F70 HydrophobicContact CB-CE1 3.66Å; A49-F70 HydrophobicContact CB-CZ 4.07Å; N53-F70 PolarHBondContact ND2-O 3.5Å; F70-S83 VanDerWaalsContact CB-O 3.28Å; F70-S83 WeakPolarHBondContact CB-O 3.31Å; F70-S83 PolarHBondContact N-O 3.4Å; F70-R85 HydrophobicContact CB-CB 4.3Å; F70-R85 HydrophobicContact CD2-CB 3.85Å; F70-R85 HydrophobicContact CD2-CG 4.42Å; F70-R85 HydrophobicContact CG-CB 4.46Å; F70-T88 HydrophobicContact CE2-CG2 3.86Å; F70-V89 HydrophobicContact CD2-CG2 4.04Å; F70-F92 AromaticContact CE2-CE2 3.66Å; F70-F92 HydrophobicContact CE2-CE2 3.66Å; F70-F92 HydrophobicContact CE2-CZ 4.3Å; F70-F92 AromaticContact CZ-CE2 3.91Å; F70-F92 HydrophobicContact CZ-CE2 3.91Å; F70-F92 HydrophobicContact CZ-CZ 4.35Å; F70-V170 HydrophobicContact CE1-CB 4.22Å; F70-V170 HydrophobicContact CE1-CG1 3.94Å; F70-V170 HydrophobicContact CZ-CB 3.99Å; F70-V170 HydrophobicContact CZ-CG1 3.92Å
71W94.1Very high90Very high55 Ų5562.5 Ų62.521%0.20834%0.34CS..THydrogen-bonded Turntrans-97-0.2-176.5-46.4100.8000112.8D45 E48 A49 D69 H81 S83D45-W71 HydrophobicContact CB-CH2 4Å; D45-W71 HydrophobicContact CB-CZ3 4.09Å; E48-W71 HydrophobicContact CB-CE3 3.81Å; E48-W71 HydrophobicContact CB-CZ3 4.07Å; A49-W71 HydrophobicContact CB-CE3 3.76Å; A49-W71 HydrophobicContact CB-CZ3 3.79Å; D69-W71 PolarHBondContact O-N 3.4Å; D69-W71 WeakPolarHBondContact OD1-CA 3.47Å; D69-W71 PolarHBondContact OD1-N 2.9Å; W71-H81 AromaticContact CD1-CD2 3.69Å; W71-H81 AromaticContact CD1-CG 3.86Å; W71-H81 AromaticContact NE1-CD2 3.76Å; W71-H81 AromaticContact NE1-CG 3.64Å; W71-S83 VanDerWaalsContact CD1-OG 3.28Å; W71-S83 PolarHBondContact NE1-OG 3.34Å
72G92.6Very high89.6Confident19 Ų1960.7 Ų60.720%0.19633%0.325CS..SBendtrans85.714.8-18000000114.4N53 D55 D69N53-G72 WeakPolarHBondContact OD1-CA 3.19Å; D55-G72 WeakPolarHBondContact OD2-CA 3.13Å; D69-G72 PolarHBondContact O-N 2.95Å; D69-G72 PolarHBondContact OD1-N 3.34Å
73S91.3Very high89.3Confident43 Ų4357.3 Ų57.330%0.30131%0.309SS..  trans-93.4141.1173.6-71.80000111.1N68 D69 L75N68-S73 CarbonylContact C-O 3.15Å; N68-S73 WeakPolarHBondContact CA-O 3.42Å; N68-S73 WeakPolarHBondContact CB-O 3.46Å; D69-S73 PolarHBondContact N-O 3.28Å; D69-S73 PolarHBondContact OD1-N 3.45Å; S73-L75 PolarHBondContact O-N 2.75Å
74N91.1Very high89.3Confident82 Ų8254.7 Ų54.744%0.43929%0.29SS..BIsolated β-bridgetrans-61.4127.8178.3-173.7-38.3000110.9N68 S76 S77 S80N68-N74 VanDerWaalsContact OD1-CA 3.32Å; N68-N74 WeakPolarHBondContact OD1-CA 3.27Å; N74-S76 PolarHBondContact O-N 3.3Å; N74-S76 VanDerWaalsContact O-N 3.11Å; N74-S76 WeakPolarHBondContact OD1-CB 3.27Å; N74-S76 PolarHBondContact OD1-N 3.43Å; N74-S77 VanDerWaalsContact O-CB 3.24Å; N74-S77 WeakPolarHBondContact O-CB 3.29Å; N74-S77 PolarHBondContact O-N 2.94Å; N74-S80 WeakPolarHBondContact O-CB 3.49Å
75L89.6Confident89.4Confident7 Ų754 Ų544%0.03728%0.284CS..THydrogen-bonded Turntrans-56.9-27.9-178.8-74.3167.8000113.1R67 D69 S73 S77 K82 Y84 I289R67-L75 WeakPolarHBondContact O-CB 3.43Å; R67-L75 VanDerWaalsContact O-CG 3.28Å; R67-L75 WeakPolarHBondContact O-CG 3.39Å; R67-L75 PolarHBondContact O-N 2.88Å; D69-L75 HydrophobicContact CB-CD2 3.91Å; S73-L75 PolarHBondContact O-N 2.75Å; L75-S77 VanDerWaalsContact C-N 3.27Å; L75-S77 PolarHBondContact O-N 2.9Å; L75-K82 WeakPolarHBondContact O-CE 3.38Å; L75-K82 PolarHBondContact O-NZ 2.98Å; L75-Y84 HydrophobicContact CD1-CD2 3.68Å; L75-Y84 HydrophobicContact CD1-CE2 4.04Å; L75-Y84 HydrophobicContact CD1-CG 4.48Å; L75-I289 HydrophobicContact CD1-CG2 3.83Å
76S86.6Confident89.5Confident105 Ų10553.9 Ų53.973%0.73428%0.283SS*.THydrogen-bonded Turntrans-75.7-13.8177.8-53.50000113.5N74N74-S76 PolarHBondContact O-N 3.3Å; N74-S76 VanDerWaalsContact O-N 3.11Å; N74-S76 WeakPolarHBondContact OD1-CB 3.27Å; N74-S76 PolarHBondContact OD1-N 3.43Å
77S83.8Confident89.6Confident46 Ų4650.1 Ų50.132%0.32227%0.271SS..SBendtrans-73.1145.9178.4-173.30000111.8N74 L75 S79 S80N74-S77 VanDerWaalsContact O-CB 3.24Å; N74-S77 WeakPolarHBondContact O-CB 3.29Å; N74-S77 PolarHBondContact O-N 2.94Å; L75-S77 VanDerWaalsContact C-N 3.27Å; L75-S77 PolarHBondContact O-N 2.9Å; S77-S79 PolarHBondContact O-N 3.5Å; S77-S79 PolarHBondContact OG-N 3.49Å; S77-S79 PolarHBondContact OG-OG 3.33Å; S77-S80 WeakPolarHBondContact O-CB 3.45Å; S77-S80 PolarHBondContact O-N 2.99Å
78N77.4Confident89.8Confident166 Ų16642.1 Ų42.189%0.88824%0.241SC*.THydrogen-bonded Turntrans-68.6-21.9170.4-69.6-11.7000112.5S80N78-S80 VanDerWaalsContact C-N 3.27Å
79S72.9Confident90Very high83 Ų8341.5 Ų41.558%0.5824%0.238SC*.THydrogen-bonded Turntrans-81.1-5.717668.60000113.5S77S77-S79 PolarHBondContact O-N 3.5Å; S77-S79 PolarHBondContact OG-N 3.49Å; S77-S79 PolarHBondContact OG-OG 3.33Å
80S83.4Confident90.2Very high11 Ų1144.5 Ų44.58%0.07725%0.253CS..  trans-75.1139.6-180173.80000110.7D69 N74 S77 N78 K82D69-S80 WeakPolarHBondContact OD2-CA 3.46Å; D69-S80 WeakPolarHBondContact OD2-CB 3.3Å; D69-S80 PolarHBondContact OD2-OG 3.07Å; N74-S80 WeakPolarHBondContact O-CB 3.49Å; S77-S80 WeakPolarHBondContact O-CB 3.45Å; S77-S80 PolarHBondContact O-N 2.99Å; N78-S80 VanDerWaalsContact C-N 3.27Å; S80-K82 PolarHBondContact O-N 3.4Å; S80-K82 PolarHBondContact OG-N 3.29Å
81H80.9Confident90.3Very high117 Ų11746.1 Ų46.154%0.54226%0.263SS..  trans-74.5-4.4171.7-77.4-87.6000112.9D69 W71 S83D69-H81 PolarHBondContact OD2-N 3.42Å; W71-H81 AromaticContact CD1-CD2 3.69Å; W71-H81 AromaticContact CD1-CG 3.86Å; W71-H81 AromaticContact NE1-CD2 3.76Å; W71-H81 AromaticContact NE1-CG 3.64Å; H81-S83 PolarHBondContact O-N 3.3Å
82K87Confident90.5Very high34 Ų3443.5 Ų43.515%0.14825%0.253CS..  trans57.518.7-178.2-50.2-67.1-175.9161.50113.7L75 S80 Y84 M290L75-K82 WeakPolarHBondContact O-CE 3.38Å; L75-K82 PolarHBondContact O-NZ 2.98Å; S80-K82 PolarHBondContact O-N 3.4Å; S80-K82 PolarHBondContact OG-N 3.29Å; K82-Y84 PolarHBondContact O-N 3.09Å; K82-M290 HydrophobicContact CB-CE 4.11Å; K82-M290 WeakPolarHBondContact O-CE 3.44Å
83S89.4Confident90.7Very high19 Ų1943.5 Ų43.513%0.13325%0.248CC..  trans-798118045.10000110.4F70 W71 H81 R85F70-S83 VanDerWaalsContact CB-O 3.28Å; F70-S83 WeakPolarHBondContact CB-O 3.31Å; F70-S83 PolarHBondContact N-O 3.4Å; W71-S83 VanDerWaalsContact CD1-OG 3.28Å; W71-S83 PolarHBondContact NE1-OG 3.34Å; H81-S83 PolarHBondContact O-N 3.3Å; S83-R85 PolarHBondContact O-N 3.21Å
84Y93.6Very high91Very high8 Ų846.3 Ų46.33%0.03126%0.259CS..  trans-77.9104.4-176.1-173-121.4000112.8L75 K82 P86 L219 R286 I289 M290L75-Y84 HydrophobicContact CD1-CD2 3.68Å; L75-Y84 HydrophobicContact CD1-CE2 4.04Å; L75-Y84 HydrophobicContact CD1-CG 4.48Å; K82-Y84 PolarHBondContact O-N 3.09Å; Y84-P86 HydrophobicContact CD2-CG 4.49Å; Y84-P86 HydrophobicContact CE1-CG 4.02Å; Y84-P86 HydrophobicContact CE2-CB 4.32Å; Y84-P86 HydrophobicContact CE2-CG 3.92Å; Y84-L219 HydrophobicContact CD1-CD2 4.5Å; Y84-L219 HydrophobicContact CE1-CD2 3.78Å; Y84-R286 PolarHBondContact O-NH2 3.41Å; Y84-I289 HydrophobicContact CD1-CG2 4.38Å; Y84-I289 HydrophobicContact CD2-CG2 4.24Å; Y84-I289 HydrophobicContact CE1-CD1 3.98Å; Y84-I289 HydrophobicContact CE1-CG2 4.02Å; Y84-I289 HydrophobicContact CE2-CG2 3.86Å; Y84-I289 HydrophobicContact CG-CG2 4.46Å; Y84-M290 HydrophobicContact CG-CG 4.46Å
85R96.3Very high91.2Very high32 Ų3243.1 Ų43.112%0.12124%0.242CC..  trans-140.855.2-175.5-59.6-179.9-177.4164.40.9113.1F70 S83 L87 T88 V89 L219 C220 E222F70-R85 HydrophobicContact CB-CB 4.3Å; F70-R85 HydrophobicContact CD2-CB 3.85Å; F70-R85 HydrophobicContact CD2-CG 4.42Å; F70-R85 HydrophobicContact CG-CB 4.46Å; S83-R85 PolarHBondContact O-N 3.21Å; R85-L87 PolarHBondContact O-N 2.84Å; R85-T88 PolarHBondContact O-N 3.36Å; R85-V89 PolarHBondContact O-N 2.92Å; R85-L219 CarbonylContact C-O 3.6Å; R85-L219 WeakPolarHBondContact CA-O 3.43Å; R85-C220 WeakPolarHBondContact CB-O 3.24Å; R85-C220 VanDerWaalsContact CD-O 3.29Å; R85-C220 WeakPolarHBondContact CD-O 3.24Å; R85-C220 VanDerWaalsContact CG-O 3.24Å; R85-C220 WeakPolarHBondContact CG-O 3.49Å; R85-E222 IonicContact CZ-OE1 2.69Å; R85-E222 IonicContact CZ-OE2 2.73Å; R85-E222 IonicContact NE-OE2 2.78Å; R85-E222 PolarHBondContact NE-OE2 3.32Å; R85-E222 IonicContact NH2-OE1 2.99Å; R85-E222 PolarHBondContact NH2-OE1 3.18Å; R85-E222 IonicContact NH2-OE2 3.45Å
86P97.3Very high91.6Very high1 Ų145.2 Ų45.21%0.00625%0.249CC..Hα-helixtrans-62.9-35.9-168.926.3-37.2000113.8I65 W66 Y84 T88 V89 L90 L219I65-P86 HydrophobicContact CG2-CB 3.7Å; I65-P86 WeakPolarHBondContact CG2-O 3.19Å; I65-P86 WeakPolarHBondContact O-CB 3.38Å; W66-P86 HydrophobicContact CD2-CB 4.33Å; W66-P86 HydrophobicContact CE3-CB 3.93Å; W66-P86 HydrophobicContact CE3-CG 3.93Å; W66-P86 HydrophobicContact CZ3-CB 4.09Å; W66-P86 HydrophobicContact CZ3-CG 3.81Å; Y84-P86 HydrophobicContact CD2-CG 4.49Å; Y84-P86 HydrophobicContact CE1-CG 4.02Å; Y84-P86 HydrophobicContact CE2-CB 4.32Å; Y84-P86 HydrophobicContact CE2-CG 3.92Å; P86-T88 VanDerWaalsContact C-N 3.34Å; P86-T88 PolarHBondContact O-N 3.34Å; P86-V89 PolarHBondContact O-N 3.46Å; P86-L90 WeakPolarHBondContact O-CB 3.46Å; P86-L90 PolarHBondContact O-N 2.9Å; P86-L219 VanDerWaalsContact CD-O 3.3Å; P86-L219 WeakPolarHBondContact CD-O 3.44Å; P86-L219 HydrophobicContact CG-CB 4.25Å; P86-L219 HydrophobicContact CG-CD2 3.77Å
87L97.9Very high92Very high37 Ų3744.4 Ų44.419%0.19424%0.237CC..Hα-helixtrans-68.2-36.4-179.9-71.8-173.9000111.7W66 R85 L90 T91 A216 L219W66-L87 HydrophobicContact CH2-CD2 4.33Å; R85-L87 PolarHBondContact O-N 2.84Å; L87-L90 HydrophobicContact CD2-CD2 4.28Å; L87-L90 WeakPolarHBondContact O-CB 3.29Å; L87-L90 PolarHBondContact O-N 2.96Å; L87-T91 WeakPolarHBondContact O-CG2 3.46Å; L87-T91 PolarHBondContact O-N 2.95Å; L87-A216 HydrophobicContact CD1-CB 4.04Å; L87-L219 HydrophobicContact CB-CB 4.26Å; L87-L219 HydrophobicContact CD1-CB 3.71Å; L87-L219 HydrophobicContact CD1-CD1 4.01Å; L87-L219 HydrophobicContact CG-CB 3.71Å; L87-L219 HydrophobicContact CG-CD1 4.16Å; L87-L219 PolarHBondContact N-O 3.16Å
88T98.1Very high92.6Very high0 Ų048.6 Ų48.60%025%0.254CS..Hα-helixtrans-63.6-48.7175.1-50.80000110.8F70 R85 P86 L90 T91 F92 R172 A173 L176 C220F70-T88 HydrophobicContact CE2-CG2 3.86Å; R85-T88 PolarHBondContact O-N 3.36Å; P86-T88 VanDerWaalsContact C-N 3.34Å; P86-T88 PolarHBondContact O-N 3.34Å; T88-L90 VanDerWaalsContact C-N 3.28Å; T88-L90 PolarHBondContact O-N 2.84Å; T88-T91 PolarHBondContact O-N 3.46Å; T88-T91 PolarHBondContact O-OG1 2.74Å; T88-F92 HydrophobicContact CG2-CE1 4.44Å; T88-F92 HydrophobicContact CG2-CE2 3.88Å; T88-F92 HydrophobicContact CG2-CZ 3.77Å; T88-F92 PolarHBondContact O-N 2.95Å; T88-F92 VanDerWaalsContact O-N 3.12Å; T88-R172 HydrophobicContact CG2-CB 4.28Å; T88-R172 HydrophobicContact CG2-CG 4.44Å; T88-A173 HydrophobicContact CG2-CB 3.98Å; T88-L176 HydrophobicContact CG2-CD1 4.43Å; T88-C220 VanDerWaalsContact OG1-CA 3.32Å; T88-C220 WeakPolarHBondContact OG1-CA 3.41Å; T88-C220 PolarHBondContact OG1-O 3.4Å; T88-C220 VanDerWaalsContact OG1-O 3.09Å
89V97.9Very high93.3Very high3 Ų342.5 Ų42.52%0.01823%0.227CC..Hα-helixtrans-61.2-38.3177.5179.50000111.3D55 L56 I65 F70 R85 P86 T91 F92 R93D55-V89 HydrophobicContact CB-CG1 4.14Å; L56-V89 HydrophobicContact CD1-CG1 4.02Å; I65-V89 HydrophobicContact CD1-CG1 4.42Å; I65-V89 HydrophobicContact CG1-CG1 4.22Å; I65-V89 HydrophobicContact CG2-CB 4.2Å; I65-V89 HydrophobicContact CG2-CG1 4.35Å; F70-V89 HydrophobicContact CD2-CG2 4.04Å; R85-V89 PolarHBondContact O-N 2.92Å; P86-V89 PolarHBondContact O-N 3.46Å; V89-T91 VanDerWaalsContact C-N 3.31Å; V89-T91 PolarHBondContact O-N 2.82Å; V89-F92 WeakPolarHBondContact O-CB 3.41Å; V89-F92 PolarHBondContact O-N 3.43Å; V89-F92 VanDerWaalsContact O-N 3.13Å; V89-R93 PolarHBondContact O-N 3.06Å
90L97.6Very high94.3Very high64 Ų6441.7 Ų41.734%0.33523%0.232SC..Hα-helixtrans-58.9-41.8173.8-179.763.7000111.8L62 I65 P86 L87 T88 F92 R93 L94L62-L90 HydrophobicContact CD1-CD1 3.84Å; I65-L90 HydrophobicContact CD1-CB 4.41Å; I65-L90 HydrophobicContact CD1-CD1 4.16Å; P86-L90 WeakPolarHBondContact O-CB 3.46Å; P86-L90 PolarHBondContact O-N 2.9Å; L87-L90 HydrophobicContact CD2-CD2 4.28Å; L87-L90 WeakPolarHBondContact O-CB 3.29Å; L87-L90 PolarHBondContact O-N 2.96Å; T88-L90 VanDerWaalsContact C-N 3.28Å; T88-L90 PolarHBondContact O-N 2.84Å; L90-F92 VanDerWaalsContact C-N 3.34Å; L90-F92 PolarHBondContact O-N 3.48Å; L90-R93 PolarHBondContact O-N 3.3Å; L90-L94 PolarHBondContact O-N 2.91Å
91T97.9Very high94.8Very high36 Ų3641.6 Ų41.622%0.22123%0.232CC..Hα-helixtrans-66.6-34.6175.471.90000112.7L87 T88 V89 L94 N95 R172 L176L87-T91 WeakPolarHBondContact O-CG2 3.46Å; L87-T91 PolarHBondContact O-N 2.95Å; T88-T91 PolarHBondContact O-N 3.46Å; T88-T91 PolarHBondContact O-OG1 2.74Å; V89-T91 VanDerWaalsContact C-N 3.31Å; V89-T91 PolarHBondContact O-N 2.82Å; T91-L94 PolarHBondContact O-N 3.43Å; T91-N95 WeakPolarHBondContact O-CB 3.4Å; T91-N95 PolarHBondContact O-N 3.41Å; T91-R172 PolarHBondContact O-NH1 3.32Å; T91-R172 WeakPolarHBondContact OG1-CD 3.41Å; T91-L176 HydrophobicContact CG2-CD1 3.63Å
92F97.9Very high95.5Very high0 Ų039 Ų390%022%0.222CC..Hα-helixtrans-64.9-43.7173.6-62.7-35.9000111.5L56 F70 T88 V89 L90 N95 Y96 F107 V169 R172L56-F92 HydrophobicContact CD1-CB 4.16Å; L56-F92 HydrophobicContact CD2-CB 3.83Å; L56-F92 HydrophobicContact CG-CB 3.95Å; F70-F92 AromaticContact CE2-CE2 3.66Å; F70-F92 HydrophobicContact CE2-CE2 3.66Å; F70-F92 HydrophobicContact CE2-CZ 4.3Å; F70-F92 AromaticContact CZ-CE2 3.91Å; F70-F92 HydrophobicContact CZ-CE2 3.91Å; F70-F92 HydrophobicContact CZ-CZ 4.35Å; T88-F92 HydrophobicContact CG2-CE1 4.44Å; T88-F92 HydrophobicContact CG2-CE2 3.88Å; T88-F92 HydrophobicContact CG2-CZ 3.77Å; T88-F92 PolarHBondContact O-N 2.95Å; T88-F92 VanDerWaalsContact O-N 3.12Å; V89-F92 WeakPolarHBondContact O-CB 3.41Å; V89-F92 PolarHBondContact O-N 3.43Å; V89-F92 VanDerWaalsContact O-N 3.13Å; L90-F92 VanDerWaalsContact C-N 3.34Å; L90-F92 PolarHBondContact O-N 3.48Å; F92-N95 WeakPolarHBondContact O-CB 3.28Å; F92-N95 PolarHBondContact O-N 2.92Å; F92-Y96 PolarHBondContact O-N 3.38Å; F92-F107 HydrophobicContact CB-CE1 4.09Å; F92-F107 HydrophobicContact CD1-CD1 4.04Å; F92-F107 HydrophobicContact CD1-CE1 4.09Å; F92-F107 HydrophobicContact CG-CE1 4.47Å; F92-V169 HydrophobicContact CD1-CG1 4.44Å; F92-V169 HydrophobicContact CE1-CG1 3.89Å; F92-R172 HydrophobicContact CE1-CB 3.73Å; F92-R172 HydrophobicContact CE1-CG 4.22Å; F92-R172 HydrophobicContact CZ-CB 4Å
93R97.1Very high95.9Very high20 Ų2042.6 Ų42.68%0.07524%0.239CC..Hα-helixtrans-62.2-43.7176.3-175.7176.1-179.1145.7-3.6111.9D55 T60 V89 L90 N95 Y96 L97D55-R93 WeakPolarHBondContact O-CD 3.38Å; D55-R93 PolarHBondContact O-NH1 3Å; T60-R93 PolarHBondContact O-NH1 3.27Å; T60-R93 PolarHBondContact O-NH2 3.33Å; V89-R93 PolarHBondContact O-N 3.06Å; L90-R93 PolarHBondContact O-N 3.3Å; R93-N95 VanDerWaalsContact C-N 3.3Å; R93-N95 PolarHBondContact O-N 2.99Å; R93-Y96 WeakPolarHBondContact O-CB 3.35Å; R93-Y96 PolarHBondContact O-N 3.34Å; R93-L97 HydrophobicContact CG-CD1 4.38Å; R93-L97 WeakPolarHBondContact O-CG 3.25Å; R93-L97 PolarHBondContact O-N 3.41Å
94L96.6Very high96.2Very high101 Ų10143.3 Ų43.353%0.52924%0.243SC..Hα-helixtrans-61.3-41.9175.5-178.361.1000111.2L90 T91 Y96 L97 I98L90-L94 PolarHBondContact O-N 2.91Å; T91-L94 PolarHBondContact O-N 3.43Å; L94-Y96 PolarHBondContact O-N 3.48Å; L94-L97 PolarHBondContact O-N 2.97Å; L94-I98 HydrophobicContact CD1-CD1 4Å; L94-I98 HydrophobicContact CD1-CG1 4.26Å; L94-I98 HydrophobicContact CD2-CD1 4.49Å; L94-I98 HydrophobicContact CG-CD1 3.81Å; L94-I98 HydrophobicContact CG-CG1 4.47Å; L94-I98 VanDerWaalsContact O-CG1 3.3Å; L94-I98 WeakPolarHBondContact O-CG1 3.41Å; L94-I98 PolarHBondContact O-N 2.9Å
95N96.8Very high96.4Very high16 Ų1646.2 Ų46.29%0.08626%0.262CS..Hα-helixtrans-63.2-41.4177-153.9139.3000112.1T91 F92 R93 A99 G106 F107 R172T91-N95 WeakPolarHBondContact O-CB 3.4Å; T91-N95 PolarHBondContact O-N 3.41Å; F92-N95 WeakPolarHBondContact O-CB 3.28Å; F92-N95 PolarHBondContact O-N 2.92Å; R93-N95 VanDerWaalsContact C-N 3.3Å; R93-N95 PolarHBondContact O-N 2.99Å; N95-A99 WeakPolarHBondContact O-CB 3.29Å; N95-A99 PolarHBondContact O-N 2.9Å; N95-G106 PolarHBondContact OD1-O 3.43Å; N95-F107 HydrophobicContact CB-CD1 4.06Å; N95-F107 HydrophobicContact CB-CE1 3.69Å; N95-F107 HydrophobicContact CB-CE2 4.18Å; N95-F107 HydrophobicContact CB-CG 4.47Å; N95-F107 HydrophobicContact CB-CZ 3.75Å; N95-R172 PolarHBondContact OD1-NH1 3.17Å; N95-R172 PolarHBondContact OD1-NH2 3.29Å
96Y96.6Very high96.4Very high50 Ų5046.3 Ų46.320%0.19627%0.272CS..Hα-helixtrans-59.4-45.7173.7176.6-78.5000111.1P58 F92 R93 L94 A99 G100 G101 L102P58-Y96 VanDerWaalsContact CD-CE1 3.48Å; P58-Y96 HydrophobicContact CG-CD1 4.42Å; P58-Y96 HydrophobicContact CG-CE1 3.79Å; F92-Y96 PolarHBondContact O-N 3.38Å; R93-Y96 WeakPolarHBondContact O-CB 3.35Å; R93-Y96 PolarHBondContact O-N 3.34Å; L94-Y96 PolarHBondContact O-N 3.48Å; Y96-A99 PolarHBondContact O-N 3.39Å; Y96-G100 PolarHBondContact O-N 3.17Å; Y96-G101 PolarHBondContact O-N 3.42Å; Y96-L102 HydrophobicContact CD2-CD2 3.79Å; Y96-L102 HydrophobicContact CD2-CG 3.92Å; Y96-L102 HydrophobicContact CE2-CD2 4.21Å; Y96-L102 HydrophobicContact CE2-CG 3.85Å
97L95.4Very high96.4Very high89 Ų8946.2 Ų46.247%0.46627%0.272SS..Hα-helixtrans-65.6-44.1-179.3-70.5172.2000112.4P58 R93 L94 G100P58-L97 HydrophobicContact CB-CD2 4.3Å; P58-L97 HydrophobicContact CG-CD2 3.85Å; R93-L97 HydrophobicContact CG-CD1 4.38Å; R93-L97 WeakPolarHBondContact O-CG 3.25Å; R93-L97 PolarHBondContact O-N 3.41Å; L94-L97 PolarHBondContact O-N 2.97Å; L97-G100 PolarHBondContact O-N 2.85Å
98I95.4Very high96.4Very high133 Ų13344.5 Ų44.568%0.68226%0.263SS*.Hα-helixtrans-65.1-40.9178.9-68.4168.3000111L94 G100L94-I98 HydrophobicContact CD1-CD1 4Å; L94-I98 HydrophobicContact CD1-CG1 4.26Å; L94-I98 HydrophobicContact CD2-CD1 4.49Å; L94-I98 HydrophobicContact CG-CD1 3.81Å; L94-I98 HydrophobicContact CG-CG1 4.47Å; L94-I98 VanDerWaalsContact O-CG1 3.3Å; L94-I98 WeakPolarHBondContact O-CG1 3.41Å; L94-I98 PolarHBondContact O-N 2.9Å; I98-G100 VanDerWaalsContact C-N 3.3Å; I98-G100 PolarHBondContact O-N 3.47Å
99A93.8Very high96.4Very high39 Ų3947.1 Ų47.132%0.32228%0.278SS..Hα-helixtrans-78.4-13.2-179.900000113.5N95 Y96 G101 H103N95-A99 WeakPolarHBondContact O-CB 3.29Å; N95-A99 PolarHBondContact O-N 2.9Å; Y96-A99 PolarHBondContact O-N 3.39Å; A99-G101 VanDerWaalsContact C-N 3.29Å; A99-H103 HydrophobicContact CB-CB 4.3Å; A99-H103 PolarHBondContact O-CD2 3.26Å; A99-H103 VanDerWaalsContact O-CD2 3.32Å
100G93.1Very high96.4Very high66 Ų6649.8 Ų49.868%0.6829%0.292SS*.THydrogen-bonded Turntrans73.816.2-173.900000114.3Y96 L97 I98Y96-G100 PolarHBondContact O-N 3.17Å; L97-G100 PolarHBondContact O-N 2.85Å; I98-G100 VanDerWaalsContact C-N 3.3Å; I98-G100 PolarHBondContact O-N 3.47Å
101G94.3Very high96.5Very high8 Ų846.8 Ų46.88%0.08228%0.276CS..SBendtrans160.6-167.7-176.400000114.5Y96 A99 H103Y96-G101 PolarHBondContact O-N 3.42Å; A99-G101 VanDerWaalsContact C-N 3.29Å; G101-H103 PolarHBondContact O-N 3.46Å
102L95.1Very high96.5Very high63 Ų6345.3 Ų45.333%0.3327%0.267SS..  trans-84.882175.1-71.8173.7000110.2F42 I50 V51 Y96F42-L102 HydrophobicContact CE2-CB 4.05Å; F42-L102 HydrophobicContact CE2-CD2 4.38Å; F42-L102 HydrophobicContact CZ-CD2 4.46Å; I50-L102 HydrophobicContact CG2-CD2 3.8Å; V51-L102 HydrophobicContact CB-CD1 4.45Å; V51-L102 HydrophobicContact CG1-CD1 4.18Å; Y96-L102 HydrophobicContact CD2-CD2 3.79Å; Y96-L102 HydrophobicContact CD2-CG 3.92Å; Y96-L102 HydrophobicContact CE2-CD2 4.21Å; Y96-L102 HydrophobicContact CE2-CG 3.85Å
103H95.3Very high96.5Very high110 Ų11049.4 Ų49.451%0.50929%0.288SS..  trans-109.8108.6173.9-65.2-68.1000110.3A99 G101 V105 F107A99-H103 HydrophobicContact CB-CB 4.3Å; A99-H103 PolarHBondContact O-CD2 3.26Å; A99-H103 VanDerWaalsContact O-CD2 3.32Å; G101-H103 PolarHBondContact O-N 3.46Å; H103-V105 VanDerWaalsContact C-N 3.33Å; H103-V105 PolarHBondContact O-N 3.44Å; H103-F107 VanDerWaalsContact O-CD2 3.28Å; H103-F107 WeakPolarHBondContact O-CD2 3.4Å
104P96.1Very high96.6Very high33 Ų3349.3 Ų49.321%0.21429%0.289CS..Hα-helixtrans-56-39.4-172-26.532000115G40 F42 G106 F107 H108G40-P104 WeakPolarHBondContact O-CB 3.49Å; F42-P104 HydrophobicContact CD2-CG 3.85Å; F42-P104 HydrophobicContact CE1-CB 4.33Å; F42-P104 HydrophobicContact CE2-CB 4.26Å; F42-P104 HydrophobicContact CE2-CG 3.63Å; F42-P104 HydrophobicContact CG-CG 4.4Å; F42-P104 HydrophobicContact CZ-CB 4.15Å; F42-P104 HydrophobicContact CZ-CG 4.01Å; P104-G106 VanDerWaalsContact C-N 3.35Å; P104-G106 PolarHBondContact O-N 2.93Å; P104-F107 WeakPolarHBondContact O-CA 3.24Å; P104-F107 WeakPolarHBondContact O-CB 3.4Å; P104-F107 PolarHBondContact O-N 2.9Å; P104-H108 PolarHBondContact O-CD2 2.87Å; P104-H108 VanDerWaalsContact O-CD2 3.27Å; P104-H108 PolarHBondContact O-N 2.92Å; P104-H108 VanDerWaalsContact O-N 3.14Å
105V97.2Very high96.7Very high70 Ų7044.5 Ų44.542%0.42426%0.264SS..Hα-helixtrans-52.4-49.1-172.21790000112.7Y38 H103 F107 H108 V109Y38-V105 HydrophobicContact CD2-CG1 4.27Å; Y38-V105 WeakPolarHBondContact O-CA 3.05Å; H103-V105 VanDerWaalsContact C-N 3.33Å; H103-V105 PolarHBondContact O-N 3.44Å; V105-F107 PolarHBondContact O-N 3.14Å; V105-H108 PolarHBondContact O-N 2.93Å; V105-V109 HydrophobicContact CG1-CG2 4.14Å; V105-V109 WeakPolarHBondContact O-CB 3.49Å; V105-V109 VanDerWaalsContact O-CG2 3.27Å; V105-V109 WeakPolarHBondContact O-CG2 3.48Å; V105-V109 PolarHBondContact O-N 3.04Å
106G97Very high96.8Very high33 Ų3344.2 Ų44.234%0.3426%0.264SS..Hα-helixtrans-62.7-30.5-179.400000112.7N95 P104 L110N95-G106 PolarHBondContact OD1-O 3.43Å; P104-G106 VanDerWaalsContact C-N 3.35Å; P104-G106 PolarHBondContact O-N 2.93Å; G106-L110 PolarHBondContact O-N 2.92Å
107F97.9Very high96.9Very high0 Ų045 Ų450%027%0.273CS..Hα-helixtrans-73.2-45.4178.9-71.5-104000112.4F42 I50 F92 N95 H103 P104 V105 L110 N111 V169 R172F42-F107 HydrophobicContact CE1-CB 4.41Å; F42-F107 HydrophobicContact CE1-CD2 4.21Å; F42-F107 HydrophobicContact CE1-CG 4.19Å; F42-F107 AromaticContact CZ-CD2 3.99Å; F42-F107 HydrophobicContact CZ-CD2 3.99Å; F42-F107 HydrophobicContact CZ-CE2 4.15Å; F42-F107 HydrophobicContact CZ-CG 4.43Å; I50-F107 HydrophobicContact CG2-CE1 4.14Å; I50-F107 HydrophobicContact CG2-CZ 4.37Å; F92-F107 HydrophobicContact CB-CE1 4.09Å; F92-F107 HydrophobicContact CD1-CD1 4.04Å; F92-F107 HydrophobicContact CD1-CE1 4.09Å; F92-F107 HydrophobicContact CG-CE1 4.47Å; N95-F107 HydrophobicContact CB-CD1 4.06Å; N95-F107 HydrophobicContact CB-CE1 3.69Å; N95-F107 HydrophobicContact CB-CE2 4.18Å; N95-F107 HydrophobicContact CB-CG 4.47Å; N95-F107 HydrophobicContact CB-CZ 3.75Å; H103-F107 VanDerWaalsContact O-CD2 3.28Å; H103-F107 WeakPolarHBondContact O-CD2 3.4Å; P104-F107 WeakPolarHBondContact O-CA 3.24Å; P104-F107 WeakPolarHBondContact O-CB 3.4Å; P104-F107 PolarHBondContact O-N 2.9Å; V105-F107 PolarHBondContact O-N 3.14Å; F107-L110 PolarHBondContact O-N 3.37Å; F107-N111 PolarHBondContact O-N 3.38Å; F107-V169 HydrophobicContact CB-CB 4.5Å; F107-V169 HydrophobicContact CB-CG1 3.6Å; F107-V169 HydrophobicContact CB-CG2 4.01Å; F107-V169 HydrophobicContact CD1-CG1 3.76Å; F107-V169 HydrophobicContact CG-CG1 4.09Å; F107-R172 VanDerWaalsContact CA-NH2 3.26Å; F107-R172 PolarHBondContact O-NH2 2.71Å
108H98.1Very high97Very high1 Ų140.7 Ų40.71%0.00525%0.251CS..Hα-helixtrans-66.5-44.2177.4-68.3-74.3000111.7G40 E41 P104 V105 L110 N111 I112 A167 V169G40-H108 PolarHBondContact O-CD2 3.5Å; G40-H108 PolarHBondContact O-NE2 2.99Å; E41-H108 PolarHBondContact O-NE2 2.86Å; P104-H108 PolarHBondContact O-CD2 2.87Å; P104-H108 VanDerWaalsContact O-CD2 3.27Å; P104-H108 PolarHBondContact O-N 2.92Å; P104-H108 VanDerWaalsContact O-N 3.14Å; V105-H108 PolarHBondContact O-N 2.93Å; H108-L110 VanDerWaalsContact C-N 3.28Å; H108-L110 PolarHBondContact O-N 3.44Å; H108-N111 PolarHBondContact O-N 3.2Å; H108-N111 VanDerWaalsContact O-N 3.09Å; H108-I112 WeakPolarHBondContact O-CG1 3.39Å; H108-I112 PolarHBondContact O-N 3.41Å; H108-A167 PolarHBondContact CE1-O 3.48Å; H108-A167 PolarHBondContact ND1-O 2.83Å; H108-V169 WeakPolarHBondContact CE1-CG2 3.04Å
109V98.1Very high97.2Very high54 Ų5434.4 Ų34.433%0.32722%0.219SC..Hα-helixtrans-57.4-42.4177.6169.30000111.2V105 N111 I112 I113V105-V109 HydrophobicContact CG1-CG2 4.14Å; V105-V109 WeakPolarHBondContact O-CB 3.49Å; V105-V109 VanDerWaalsContact O-CG2 3.27Å; V105-V109 WeakPolarHBondContact O-CG2 3.48Å; V105-V109 PolarHBondContact O-N 3.04Å; V109-N111 VanDerWaalsContact C-N 3.35Å; V109-N111 PolarHBondContact O-N 3.39Å; V109-I112 PolarHBondContact O-N 3.44Å; V109-I113 HydrophobicContact CG1-CD1 3.74Å; V109-I113 HydrophobicContact CG1-CG1 4.39Å; V109-I113 VanDerWaalsContact O-CG1 3.3Å; V109-I113 WeakPolarHBondContact O-CG1 3.3Å; V109-I113 PolarHBondContact O-N 2.96Å
110L98Very high97.3Very high60 Ų6033.8 Ų33.831%0.31421%0.211SC..Hα-helixtrans-63.3-39.6177.2-17857.4000112.3G106 F107 H108 I113 L114G106-L110 PolarHBondContact O-N 2.92Å; F107-L110 PolarHBondContact O-N 3.37Å; H108-L110 VanDerWaalsContact C-N 3.28Å; H108-L110 PolarHBondContact O-N 3.44Å; L110-I113 PolarHBondContact O-N 2.99Å; L110-L114 HydrophobicContact CD1-CD1 4.49Å; L110-L114 HydrophobicContact CD1-CG 4.28Å; L110-L114 HydrophobicContact CG-CD1 4.17Å; L110-L114 HydrophobicContact CG-CG 4.45Å; L110-L114 WeakPolarHBondContact O-CB 3.32Å; L110-L114 VanDerWaalsContact O-CG 3.25Å; L110-L114 WeakPolarHBondContact O-CG 3.32Å; L110-L114 PolarHBondContact O-N 3.36Å
111N98.4Very high97.4Very high0 Ų032.2 Ų32.20%019%0.187CC..Hα-helixtrans-64.7-42.8176.4-75.413.5000111.6F107 H108 V109 I113 L114 H115 V166 G168 V169 R172 L175F107-N111 PolarHBondContact O-N 3.38Å; H108-N111 PolarHBondContact O-N 3.2Å; H108-N111 VanDerWaalsContact O-N 3.09Å; V109-N111 VanDerWaalsContact C-N 3.35Å; V109-N111 PolarHBondContact O-N 3.39Å; N111-I113 VanDerWaalsContact C-N 3.35Å; N111-I113 PolarHBondContact O-N 2.88Å; N111-L114 PolarHBondContact O-N 2.96Å; N111-H115 PolarHBondContact O-N 2.72Å; N111-V166 VanDerWaalsContact CB-O 3.31Å; N111-V166 WeakPolarHBondContact CB-O 3.45Å; N111-G168 PolarHBondContact ND2-O 2.93Å; N111-G168 VanDerWaalsContact ND2-O 3.13Å; N111-V169 WeakPolarHBondContact ND2-CA 3.27Å; N111-V169 PolarHBondContact ND2-O 3.49Å; N111-V169 VanDerWaalsContact ND2-O 3.13Å; N111-R172 WeakPolarHBondContact OD1-CB 3.42Å; N111-R172 PolarHBondContact OD1-NE 3.45Å; N111-L175 HydrophobicContact CB-CD1 3.59Å; N111-L175 VanDerWaalsContact O-CD1 3.29Å; N111-L175 WeakPolarHBondContact O-CD1 3.37Å
112I98.6Very high97.5Very high6 Ų632 Ų323%0.03118%0.184CC..Hα-helixtrans-60.3-45.2176.1-66164.8000110.7L31 F34 H108 V109 H115 A116 V166L31-I112 HydrophobicContact CD2-CG2 3.64Å; F34-I112 HydrophobicContact CB-CG1 4.15Å; F34-I112 WeakPolarHBondContact O-CD1 3.45Å; H108-I112 WeakPolarHBondContact O-CG1 3.39Å; H108-I112 PolarHBondContact O-N 3.41Å; V109-I112 PolarHBondContact O-N 3.44Å; I112-H115 PolarHBondContact O-N 2.92Å; I112-A116 PolarHBondContact O-N 3.42Å; I112-V166 HydrophobicContact CG1-CG1 4.05Å
113I98.5Very high97.4Very high85 Ų8529 Ų2944%0.43617%0.168SC..Hα-helixtrans-62.8-45.9176.7-68.8168000111V109 L110 N111 H115 A116 V117V109-I113 HydrophobicContact CG1-CD1 3.74Å; V109-I113 HydrophobicContact CG1-CG1 4.39Å; V109-I113 VanDerWaalsContact O-CG1 3.3Å; V109-I113 WeakPolarHBondContact O-CG1 3.3Å; V109-I113 PolarHBondContact O-N 2.96Å; L110-I113 PolarHBondContact O-N 2.99Å; N111-I113 VanDerWaalsContact C-N 3.35Å; N111-I113 PolarHBondContact O-N 2.88Å; I113-H115 VanDerWaalsContact C-N 3.33Å; I113-H115 PolarHBondContact O-N 3.28Å; I113-A116 PolarHBondContact O-N 3.35Å; I113-V117 HydrophobicContact CG2-CG2 4.44Å; I113-V117 WeakPolarHBondContact O-CG2 3.34Å; I113-V117 PolarHBondContact O-N 3.43Å
114L98.7Very high97.2Very high19 Ų1925 Ų2510%0.09915%0.151CC..Hα-helixtrans-57.8-46.7177.5-76.4170.2000110.9L110 N111 A116 V117 I118 R172 L175 L176 L179L110-L114 HydrophobicContact CD1-CD1 4.49Å; L110-L114 HydrophobicContact CD1-CG 4.28Å; L110-L114 HydrophobicContact CG-CD1 4.17Å; L110-L114 HydrophobicContact CG-CG 4.45Å; L110-L114 WeakPolarHBondContact O-CB 3.32Å; L110-L114 VanDerWaalsContact O-CG 3.25Å; L110-L114 WeakPolarHBondContact O-CG 3.32Å; L110-L114 PolarHBondContact O-N 3.36Å; N111-L114 PolarHBondContact O-N 2.96Å; L114-A116 PolarHBondContact O-N 3.13Å; L114-V117 PolarHBondContact O-N 3.09Å; L114-I118 HydrophobicContact CB-CD1 4.48Å; L114-I118 WeakPolarHBondContact O-CB 3.44Å; L114-I118 VanDerWaalsContact O-CD1 3.24Å; L114-I118 WeakPolarHBondContact O-CD1 3.14Å; L114-I118 WeakPolarHBondContact O-CG1 3.33Å; L114-I118 PolarHBondContact O-N 3.42Å; L114-R172 HydrophobicContact CD1-CG 4.14Å; L114-L175 HydrophobicContact CB-CB 4.09Å; L114-L175 HydrophobicContact CB-CD1 4.12Å; L114-L175 HydrophobicContact CD1-CB 4.28Å; L114-L176 HydrophobicContact CD1-CD2 3.95Å; L114-L176 HydrophobicContact CD1-CG 4.28Å; L114-L176 HydrophobicContact CD2-CD2 4.08Å; L114-L179 HydrophobicContact CD2-CD2 3.97Å
115H98.6Very high97Very high0 Ų023.8 Ų23.80%014%0.142CC..Hα-helixtrans-60.3-43.8176.7179.863.6000112.4F34 N111 I112 I113 V117 I118 S119 A157 H162 V166 L175 Y414F34-H115 AromaticContact CD2-CD2 3.59Å; F34-H115 AromaticContact CE2-CD2 3.51Å; F34-H115 AromaticContact CE2-NE2 3.45Å; F34-H115 WeakPolarHBondContact CE2-NE2 3.34Å; N111-H115 PolarHBondContact O-N 2.72Å; I112-H115 PolarHBondContact O-N 2.92Å; I113-H115 VanDerWaalsContact C-N 3.33Å; I113-H115 PolarHBondContact O-N 3.28Å; H115-V117 VanDerWaalsContact C-N 3.35Å; H115-V117 PolarHBondContact O-N 3.38Å; H115-I118 PolarHBondContact O-N 3.22Å; H115-S119 PolarHBondContact CE1-OG 3.11Å; H115-S119 VanDerWaalsContact CE1-OG 3.32Å; H115-S119 PolarHBondContact NE2-OG 3.2Å; H115-S119 WeakPolarHBondContact O-CB 3.14Å; H115-S119 PolarHBondContact O-N 3Å; H115-S119 PolarHBondContact O-OG 3.35Å; H115-S119 VanDerWaalsContact O-OG 3.07Å; H115-A157 PolarHBondContact NE2-O 2.65Å; H115-H162 AromaticContact CE1-ND1 3.25Å; H115-H162 PolarHBondContact CE1-ND1 3.47Å; H115-H162 VanDerWaalsContact CE1-ND1 3.25Å; H115-V166 HydrophobicContact CB-CG1 4.12Å; H115-V166 HydrophobicContact CB-CG2 3.69Å; H115-L175 HydrophobicContact CB-CD2 4.2Å; H115-Y414 AromaticContact ND1-CE2 3.78Å; H115-Y414 AromaticContact ND1-CZ 3.7Å; H115-Y414 PolarHBondContact ND1-OH 3.25Å
116A98.6Very high96.8Very high10 Ų1020.4 Ų20.48%0.08312%0.122CC..Hα-helixtrans-59.5-43.7175.800000112.2A30 L31 I112 I113 L114 S119 V120A30-A116 HydrophobicContact CB-CB 4.05Å; L31-A116 HydrophobicContact CD2-CB 4.38Å; I112-A116 PolarHBondContact O-N 3.42Å; I113-A116 PolarHBondContact O-N 3.35Å; L114-A116 PolarHBondContact O-N 3.13Å; A116-S119 PolarHBondContact O-N 3.31Å; A116-V120 VanDerWaalsContact O-CG2 3.27Å; A116-V120 WeakPolarHBondContact O-CG2 2.94Å; A116-V120 PolarHBondContact O-N 2.99Å
117V98.6Very high96.4Very high65 Ų6519 Ų1939%0.39411%0.107SC..Hα-helixtrans-63.1-46.4176.7171.90000111.5I113 L114 H115 S119 V120 L121 L179I113-V117 HydrophobicContact CG2-CG2 4.44Å; I113-V117 WeakPolarHBondContact O-CG2 3.34Å; I113-V117 PolarHBondContact O-N 3.43Å; L114-V117 PolarHBondContact O-N 3.09Å; H115-V117 VanDerWaalsContact C-N 3.35Å; H115-V117 PolarHBondContact O-N 3.38Å; V117-S119 VanDerWaalsContact C-N 3.31Å; V117-S119 PolarHBondContact O-N 3.25Å; V117-V120 PolarHBondContact O-N 3.43Å; V117-L121 HydrophobicContact CG1-CD1 4.09Å; V117-L121 HydrophobicContact CG1-CG 4.5Å; V117-L121 WeakPolarHBondContact O-CG 3.12Å; V117-L121 PolarHBondContact O-N 3.01Å; V117-L179 HydrophobicContact CG1-CD1 4.04Å
118I98.6Very high95.9Very high0 Ų019.3 Ų19.30%011%0.109CC..Hα-helixtrans-60.6-42.3178.7-67.8161.3000110.7L114 H115 L121 M122 F156 L175 A178 L179 Q182 Y414L114-I118 HydrophobicContact CB-CD1 4.48Å; L114-I118 WeakPolarHBondContact O-CB 3.44Å; L114-I118 VanDerWaalsContact O-CD1 3.24Å; L114-I118 WeakPolarHBondContact O-CD1 3.14Å; L114-I118 WeakPolarHBondContact O-CG1 3.33Å; L114-I118 PolarHBondContact O-N 3.42Å; H115-I118 PolarHBondContact O-N 3.22Å; I118-L121 PolarHBondContact O-N 3.25Å; I118-M122 WeakPolarHBondContact O-CG 3.08Å; I118-M122 PolarHBondContact O-N 3.46Å; I118-M122 VanDerWaalsContact O-N 3.07Å; I118-F156 HydrophobicContact CG2-CE1 4.01Å; I118-F156 HydrophobicContact CG2-CZ 4.31Å; I118-L175 HydrophobicContact CD1-CB 3.92Å; I118-L175 HydrophobicContact CD1-CD2 4.17Å; I118-L175 WeakPolarHBondContact CD1-O 3.3Å; I118-A178 HydrophobicContact CD1-CB 4.33Å; I118-A178 HydrophobicContact CG2-CB 4.25Å; I118-L179 HydrophobicContact CD1-CB 4.26Å; I118-L179 HydrophobicContact CG1-CB 3.96Å; I118-L179 HydrophobicContact CG1-CD1 4.32Å; I118-Q182 PolarHBondContact O-NE2 3.07Å; I118-Q182 PolarHBondContact O-OE1 2.9Å; I118-Y414 HydrophobicContact CG2-CE1 4.17Å
119S98.4Very high95.4Very high0 Ų019.3 Ų19.30%011%0.109CC..Hα-helixtrans-67-38.6177.9-68.20000112.2V26 H115 A116 V117 M122V26-S119 WeakPolarHBondContact CG1-O 3.22Å; H115-S119 PolarHBondContact CE1-OG 3.11Å; H115-S119 VanDerWaalsContact CE1-OG 3.32Å; H115-S119 PolarHBondContact NE2-OG 3.2Å; H115-S119 WeakPolarHBondContact O-CB 3.14Å; H115-S119 PolarHBondContact O-N 3Å; H115-S119 PolarHBondContact O-OG 3.35Å; H115-S119 VanDerWaalsContact O-OG 3.07Å; A116-S119 PolarHBondContact O-N 3.31Å; V117-S119 VanDerWaalsContact C-N 3.31Å; V117-S119 PolarHBondContact O-N 3.25Å; S119-M122 WeakPolarHBondContact O-CB 3.4Å; S119-M122 PolarHBondContact O-N 3.44Å
120V96.8Very high94.8Very high27 Ų2716.9 Ų16.916%0.1649%0.094CC..Hα-helixtrans-63.7-44.5174.2166.20000111.9K23 A27 A116 V117 M122 I123K23-V120 HydrophobicContact CB-CG1 3.84Å; K23-V120 HydrophobicContact CD-CG1 3.94Å; K23-V120 HydrophobicContact CG-CG1 3.77Å; K23-V120 WeakPolarHBondContact O-CG2 3.38Å; A27-V120 HydrophobicContact CB-CG2 3.79Å; A116-V120 VanDerWaalsContact O-CG2 3.27Å; A116-V120 WeakPolarHBondContact O-CG2 2.94Å; A116-V120 PolarHBondContact O-N 2.99Å; V117-V120 PolarHBondContact O-N 3.43Å; V120-M122 VanDerWaalsContact C-N 3.25Å; V120-M122 PolarHBondContact O-N 3.41Å; V120-I123 WeakPolarHBondContact O-CB 3.41Å; V120-I123 PolarHBondContact O-N 3.2Å
121L95.6Very high93.7Very high33 Ų3316 Ų1617%0.17310%0.099CC..Hα-helixtrans-66.1-27.7178-72.4175.4000112.5V117 I118 I123 D124 V125 L179 L183 L186V117-L121 HydrophobicContact CG1-CD1 4.09Å; V117-L121 HydrophobicContact CG1-CG 4.5Å; V117-L121 WeakPolarHBondContact O-CG 3.12Å; V117-L121 PolarHBondContact O-N 3.01Å; I118-L121 PolarHBondContact O-N 3.25Å; L121-I123 PolarHBondContact O-N 3.21Å; L121-D124 PolarHBondContact O-N 2.98Å; L121-V125 PolarHBondContact O-N 3.07Å; L121-L179 HydrophobicContact CD1-CD1 3.67Å; L121-L183 HydrophobicContact CD1-CD2 4.2Å; L121-L186 HydrophobicContact CD2-CD1 4.32Å
122M95.5Very high92.6Very high3 Ų316.4 Ų16.42%0.01510%0.104CC..Hα-helixtrans-61.4-26175.5-84-60.4-178.300113.7I118 S119 V120 D124 V125 F126 F156 Q182 A418I118-M122 WeakPolarHBondContact O-CG 3.08Å; I118-M122 PolarHBondContact O-N 3.46Å; I118-M122 VanDerWaalsContact O-N 3.07Å; S119-M122 WeakPolarHBondContact O-CB 3.4Å; S119-M122 PolarHBondContact O-N 3.44Å; V120-M122 VanDerWaalsContact C-N 3.25Å; V120-M122 PolarHBondContact O-N 3.41Å; M122-D124 VanDerWaalsContact C-N 3.29Å; M122-D124 PolarHBondContact O-N 3.34Å; M122-V125 PolarHBondContact O-N 3.46Å; M122-V125 HydrophobicContact SD-CB 4.03Å; M122-V125 HydrophobicContact SD-CG1 4.15Å; M122-V125 HydrophobicContact SD-CG2 4.33Å; M122-F126 HydrophobicContact CB-CD2 4.17Å; M122-F126 HydrophobicContact CB-CE2 3.83Å; M122-F126 HydrophobicContact CB-CZ 4.4Å; M122-F126 HydrophobicContact CG-CE2 4.36Å; M122-F126 HydrophobicContact CG-CZ 4.46Å; M122-F126 WeakPolarHBondContact O-CB 3.29Å; M122-F126 WeakPolarHBondContact O-CD2 3.32Å; M122-F126 VanDerWaalsContact O-CG 3.28Å; M122-F126 WeakPolarHBondContact O-CG 3.45Å; M122-F126 PolarHBondContact O-N 2.93Å; M122-F126 HydrophobicContact SD-CE1 4.28Å; M122-F126 HydrophobicContact SD-CE2 4.37Å; M122-F126 HydrophobicContact SD-CZ 4.03Å; M122-F156 HydrophobicContact CE-CE2 4.43Å; M122-F156 HydrophobicContact CE-CZ 4.37Å; M122-F156 HydrophobicContact CG-CD1 4.04Å; M122-F156 HydrophobicContact CG-CE1 4.09Å; M122-F156 HydrophobicContact CG-CG 4.39Å; M122-F156 HydrophobicContact CG-CZ 4.48Å; M122-Q182 HydrophobicContact CE-CG 3.9Å; M122-Q182 VanDerWaalsContact CG-NE2 3.31Å; M122-Q182 HydrophobicContact SD-CG 4.45Å; M122-A418 HydrophobicContact CE-CB 3.66Å; M122-A418 HydrophobicContact SD-CB 4.29Å
123I92.8Very high91.1Very high1 Ų118 Ų181%0.00511%0.112CC..Hα-helixtrans-57.6-47.3172.8-59.7175.8000109.9A22 K23 V26 V120 L121 A127 A145 A153A22-I123 HydrophobicContact CB-CD1 4.34Å; K23-I123 HydrophobicContact CG-CD1 3.96Å; V26-I123 HydrophobicContact CB-CD1 4.16Å; V26-I123 HydrophobicContact CG2-CD1 3.7Å; V26-I123 HydrophobicContact CG2-CG1 4.13Å; V120-I123 WeakPolarHBondContact O-CB 3.41Å; V120-I123 PolarHBondContact O-N 3.2Å; L121-I123 PolarHBondContact O-N 3.21Å; I123-A127 VanDerWaalsContact O-CB 3.24Å; I123-A127 WeakPolarHBondContact O-CB 3.18Å; I123-A127 PolarHBondContact O-N 3Å; I123-A145 HydrophobicContact CG2-CB 3.68Å; I123-A153 HydrophobicContact CB-CB 4.49Å; I123-A153 HydrophobicContact CG1-CB 3.5Å
124D90.8Very high89.3Confident26 Ų2618.4 Ų18.414%0.13912%0.115CC..Hα-helixtrans-69.3-40-178.4-68.6-48.3000111.2K23 L121 M122 A127 I128 N143 L186K23-D124 WeakPolarHBondContact CE-OD2 3.36Å; K23-D124 IonicContact NZ-OD1 3.56Å; K23-D124 IonicContact NZ-OD2 3.72Å; K23-D124 PolarHBondContact NZ-OD2 3.37Å; L121-D124 PolarHBondContact O-N 2.98Å; M122-D124 VanDerWaalsContact C-N 3.29Å; M122-D124 PolarHBondContact O-N 3.34Å; D124-A127 PolarHBondContact O-N 3.23Å; D124-I128 VanDerWaalsContact O-CG1 3.29Å; D124-I128 WeakPolarHBondContact O-CG1 3.24Å; D124-I128 PolarHBondContact O-N 3.19Å; D124-N143 PolarHBondContact OD1-ND2 3.1Å; D124-L186 HydrophobicContact CB-CD2 4.25Å
125V92.9Very high87.4Confident6 Ų618.2 Ų18.24%0.03611%0.113CC..Hα-helixtrans-60.7-51.6175176.30000110.7L121 M122 A127 I128 L129 Q182 F185 L186L121-V125 PolarHBondContact O-N 3.07Å; M122-V125 PolarHBondContact O-N 3.46Å; M122-V125 HydrophobicContact SD-CB 4.03Å; M122-V125 HydrophobicContact SD-CG1 4.15Å; M122-V125 HydrophobicContact SD-CG2 4.33Å; V125-A127 PolarHBondContact O-N 3.32Å; V125-I128 PolarHBondContact O-N 3.26Å; V125-L129 HydrophobicContact CG1-CD1 3.86Å; V125-L129 HydrophobicContact CG1-CG 4.43Å; V125-L129 VanDerWaalsContact O-CG 3.27Å; V125-L129 WeakPolarHBondContact O-CG 3.47Å; V125-L129 PolarHBondContact O-N 3.02Å; V125-Q182 HydrophobicContact CG2-CB 4.4Å; V125-Q182 HydrophobicContact CG2-CG 4.3Å; V125-F185 HydrophobicContact CG1-CD1 4.08Å; V125-F185 HydrophobicContact CG1-CE1 4Å; V125-F185 HydrophobicContact CG2-CD1 4.21Å; V125-L186 HydrophobicContact CG2-CD1 4.36Å; V125-L186 HydrophobicContact CG2-CD2 3.95Å; V125-L186 HydrophobicContact CG2-CG 4.1Å
126F92.9Very high85.2Confident0 Ų022.2 Ų22.20%013%0.134CC..Hα-helixtrans-65-39.1179.5-65-39.9000112.3M122 I128 L129 I130 A152 A153 L389 A418 L422M122-F126 HydrophobicContact CB-CD2 4.17Å; M122-F126 HydrophobicContact CB-CE2 3.83Å; M122-F126 HydrophobicContact CB-CZ 4.4Å; M122-F126 HydrophobicContact CG-CE2 4.36Å; M122-F126 HydrophobicContact CG-CZ 4.46Å; M122-F126 WeakPolarHBondContact O-CB 3.29Å; M122-F126 WeakPolarHBondContact O-CD2 3.32Å; M122-F126 VanDerWaalsContact O-CG 3.28Å; M122-F126 WeakPolarHBondContact O-CG 3.45Å; M122-F126 PolarHBondContact O-N 2.93Å; M122-F126 HydrophobicContact SD-CE1 4.28Å; M122-F126 HydrophobicContact SD-CE2 4.37Å; M122-F126 HydrophobicContact SD-CZ 4.03Å; F126-I128 VanDerWaalsContact C-N 3.35Å; F126-I128 PolarHBondContact O-N 3.1Å; F126-L129 PolarHBondContact O-N 3.09Å; F126-I130 WeakPolarHBondContact O-CB 3.24Å; F126-I130 WeakPolarHBondContact O-CD1 3.48Å; F126-I130 WeakPolarHBondContact O-CG1 3.48Å; F126-I130 PolarHBondContact O-N 3.07Å; F126-A152 HydrophobicContact CD2-CB 3.54Å; F126-A152 HydrophobicContact CE2-CB 3.65Å; F126-A152 HydrophobicContact CG-CB 4.1Å; F126-A152 HydrophobicContact CZ-CB 4.29Å; F126-A153 HydrophobicContact CD2-CB 4.31Å; F126-A153 HydrophobicContact CE2-CB 4.43Å; F126-L389 HydrophobicContact CE1-CD1 4.2Å; F126-A418 HydrophobicContact CE1-CB 4.19Å; F126-A418 WeakPolarHBondContact CE1-O 3.45Å; F126-A418 HydrophobicContact CZ-CB 4.01Å; F126-A418 WeakPolarHBondContact CZ-O 3.23Å; F126-L422 HydrophobicContact CD1-CB 4.21Å; F126-L422 HydrophobicContact CD1-CD1 4.19Å; F126-L422 HydrophobicContact CD1-CD2 4.24Å; F126-L422 HydrophobicContact CD1-CG 4.45Å; F126-L422 HydrophobicContact CE1-CB 4.01Å
127A88.4Confident82.9Confident3 Ų330.9 Ų30.93%0.02517%0.173CC..Hα-helixtrans-59.1-45.1175.400000111.8I123 D124 V125 G131 N143I123-A127 VanDerWaalsContact O-CB 3.24Å; I123-A127 WeakPolarHBondContact O-CB 3.18Å; I123-A127 PolarHBondContact O-N 3Å; D124-A127 PolarHBondContact O-N 3.23Å; V125-A127 PolarHBondContact O-N 3.32Å; A127-G131 WeakPolarHBondContact O-CA 3.46Å; A127-G131 PolarHBondContact O-N 2.86Å; A127-N143 HydrophobicContact CB-CB 4.3Å
128I87.8Confident80.5Confident7 Ų735.8 Ų35.84%0.03619%0.189CC..Hα-helixtrans-65.4-42.6177-69.8165.6000111.2D124 V125 F126 G132 L133 F185 L186 C189 F234 R381D124-I128 VanDerWaalsContact O-CG1 3.29Å; D124-I128 WeakPolarHBondContact O-CG1 3.24Å; D124-I128 PolarHBondContact O-N 3.19Å; V125-I128 PolarHBondContact O-N 3.26Å; F126-I128 VanDerWaalsContact C-N 3.35Å; F126-I128 PolarHBondContact O-N 3.1Å; I128-G132 VanDerWaalsContact O-CA 3.29Å; I128-G132 WeakPolarHBondContact O-CA 3.11Å; I128-G132 PolarHBondContact O-N 3.42Å; I128-L133 HydrophobicContact CG1-CD2 4.45Å; I128-L133 HydrophobicContact CG2-CD2 3.92Å; I128-F185 HydrophobicContact CG2-CE1 4.28Å; I128-F185 HydrophobicContact CG2-CZ 4.24Å; I128-L186 HydrophobicContact CD1-CD2 3.65Å; I128-C189 HydrophobicContact CD1-CB 4.48Å; I128-F234 HydrophobicContact CG2-CE2 3.7Å; I128-F234 HydrophobicContact CG2-CZ 4.01Å; I128-R381 PolarHBondContact O-NH2 2.78Å
129L87.5Confident78.1Confident1 Ų139.6 Ų39.61%0.00522%0.216CC..Hα-helixtrans-68.2-36.6-178.2-68.6175.3000112.7V125 F126 F185 F234 R381 F385 L389V125-L129 HydrophobicContact CG1-CD1 3.86Å; V125-L129 HydrophobicContact CG1-CG 4.43Å; V125-L129 VanDerWaalsContact O-CG 3.27Å; V125-L129 WeakPolarHBondContact O-CG 3.47Å; V125-L129 PolarHBondContact O-N 3.02Å; F126-L129 PolarHBondContact O-N 3.09Å; L129-F185 HydrophobicContact CD2-CE1 4.39Å; L129-F185 HydrophobicContact CD2-CE2 4.12Å; L129-F185 HydrophobicContact CD2-CZ 3.56Å; L129-F185 HydrophobicContact CG-CE1 4.48Å; L129-F185 HydrophobicContact CG-CZ 4.1Å; L129-F234 HydrophobicContact CD2-CD2 4.06Å; L129-R381 VanDerWaalsContact O-CZ 3.3Å; L129-R381 PolarHBondContact O-NE 3.4Å; L129-R381 PolarHBondContact O-NH2 3.19Å; L129-F385 HydrophobicContact CB-CB 4.27Å; L129-F385 HydrophobicContact CB-CD2 4.46Å; L129-F385 HydrophobicContact CB-CG 4.39Å; L129-F385 HydrophobicContact CD2-CB 4.23Å; L129-F385 HydrophobicContact CD2-CD1 3.67Å; L129-F385 HydrophobicContact CD2-CD2 4.22Å; L129-F385 HydrophobicContact CD2-CE1 4.04Å; L129-F385 HydrophobicContact CD2-CG 3.79Å; L129-F385 HydrophobicContact CD2-CZ 4.46Å; L129-L389 HydrophobicContact CD1-CD1 3.43Å; L129-L389 VanDerWaalsContact CD1-CD1 3.43Å; L129-L389 HydrophobicContact CD1-CG 4.19Å
130I84.6Confident75.5Confident2 Ų249 Ų491%0.0125%0.251CS..Hα-helixtrans-82.9-54.3179.2-57.8165.9000111.5L6 F126 T148 R381 T382 L422L6-I130 HydrophobicContact CD1-CG2 3.57Å; L6-I130 HydrophobicContact CD2-CG2 3.4Å; L6-I130 VanDerWaalsContact CD2-CG2 3.4Å; L6-I130 HydrophobicContact CG-CG2 4.12Å; F126-I130 WeakPolarHBondContact O-CB 3.24Å; F126-I130 WeakPolarHBondContact O-CD1 3.48Å; F126-I130 WeakPolarHBondContact O-CG1 3.48Å; F126-I130 PolarHBondContact O-N 3.07Å; I130-T148 HydrophobicContact CD1-CG2 3.81Å; I130-R381 PolarHBondContact O-NE 3.25Å; I130-R381 PolarHBondContact O-NH1 3.32Å; I130-R381 PolarHBondContact O-NH2 3.34Å; I130-T382 HydrophobicContact CG1-CG2 4.39Å; I130-L422 HydrophobicContact CD1-CD1 3.59Å; I130-L422 HydrophobicContact CG1-CD1 3.75Å
131G75.3Confident73.2Confident41 Ų4150.4 Ų50.442%0.42326%0.26SS..THydrogen-bonded Turntrans-90.4-40-169.300000113.8A127 R381A127-G131 WeakPolarHBondContact O-CA 3.46Å; A127-G131 PolarHBondContact O-N 2.86Å; G131-R381 VanDerWaalsContact C-NH1 3.32Å; G131-R381 VanDerWaalsContact C-NH2 3.35Å; G131-R381 PolarHBondContact O-NH1 2.98Å
132G74.4Confident70.9Confident10 Ų1050.8 Ų50.810%0.10326%0.264CS..  trans116.5-169.3177.300000111.5I128 D134I128-G132 VanDerWaalsContact O-CA 3.29Å; I128-G132 WeakPolarHBondContact O-CA 3.11Å; I128-G132 PolarHBondContact O-N 3.42Å; G132-D134 PolarHBondContact O-N 3.49Å
133L67.1Low68.7Low38 Ų3851.9 Ų51.920%0.19927%0.27CS..  trans-87.799.2173.5-61.2173.4000108.1I128 Y135 C189 F192 F234 L238 I239I128-L133 HydrophobicContact CG1-CD2 4.45Å; I128-L133 HydrophobicContact CG2-CD2 3.92Å; L133-Y135 HydrophobicContact CB-CE2 3.81Å; L133-C189 HydrophobicContact CD2-CB 3.84Å; L133-F192 HydrophobicContact CD1-CB 3.92Å; L133-F192 HydrophobicContact CD1-CD2 4.39Å; L133-F234 HydrophobicContact CD1-CZ 4.17Å; L133-F234 HydrophobicContact CD2-CZ 4.36Å; L133-F234 HydrophobicContact CG-CZ 4.24Å; L133-L238 HydrophobicContact CG-CD2 4.33Å; L133-I239 HydrophobicContact CD1-CD1 3.88Å
134D61.6Low67Low94 Ų9459.2 Ų59.250%0.50330%0.303SS..  trans-105.2134.5170.4-159.88.6000110.1G132 T141 V142G132-D134 PolarHBondContact O-N 3.49Å; D134-T141 CarbonylContact O-C 3.27Å; D134-T141 WeakPolarHBondContact O-CA 3.27Å; D134-V142 PolarHBondContact O-N 3.13Å
135Y58.7Low65.5Low15 Ų1558.8 Ų58.86%0.05930%0.304CS..BIsolated β-bridgetrans-129.2131.4-173.5-60.7-77.3000110.8L133 W140 T141 F192 N193 K194L133-Y135 HydrophobicContact CB-CE2 3.81Å; Y135-W140 WeakPolarHBondContact CA-O 3.28Å; Y135-T141 HydrophobicContact CD1-CG2 3.85Å; Y135-T141 HydrophobicContact CE1-CG2 3.54Å; Y135-F192 PolarHBondContact OH-O 3.04Å; Y135-N193 HydrophobicContact CE1-CB 4.49Å; Y135-N193 WeakPolarHBondContact CE1-OD1 3.49Å; Y135-N193 PolarHBondContact OH-OD1 3.35Å; Y135-K194 HydrophobicContact CD2-CB 4.31Å; Y135-K194 HydrophobicContact CD2-CG 4.43Å; Y135-K194 PolarHBondContact O-NZ 2.92Å
136D52.1Low64.9Low84 Ų8459.7 Ų59.745%0.44931%0.31SS..  trans-68.6164.2172.7-157.8-1.5000110.6K138 S139 W140 V142D136-K138 PolarHBondContact O-N 2.79Å; D136-S139 PolarHBondContact O-N 2.66Å; D136-W140 PolarHBondContact N-O 3.35Å; D136-V142 VanDerWaalsContact CA-CG2 3.49Å; D136-V142 HydrophobicContact CB-CG2 3.4Å; D136-V142 VanDerWaalsContact CB-CG2 3.4Å
137E49.9Very low64.7Low192 Ų19261.6 Ų61.690%0.89732%0.318SS*.THydrogen-bonded Turntrans-55.4-23.6174.1-66.2-168.716400112.8
138K50Low64.7Low168 Ų16861.4 Ų61.473%0.7332%0.317SS*.THydrogen-bonded Turntrans-89.912.3174.7-64.9-176.4-179.1177.30114.9D136 W140D136-K138 PolarHBondContact O-N 2.79Å; K138-W140 VanDerWaalsContact O-CD1 3.29Å; K138-W140 PolarHBondContact O-N 3.36Å
139S47.5Very low64.9Low80 Ų8061.1 Ų61.156%0.55932%0.315SS*.SBendtrans64.818180-51.50000115.7D136D136-S139 PolarHBondContact O-N 2.66Å
140W44Very low65.1Low198 Ų19861.2 Ų61.275%0.7532%0.316SS*.  trans-92.2140170.1-72.183.4000109.9Y135 D136 K138 V142Y135-W140 WeakPolarHBondContact CA-O 3.28Å; D136-W140 PolarHBondContact N-O 3.35Å; K138-W140 VanDerWaalsContact O-CD1 3.29Å; K138-W140 PolarHBondContact O-N 3.36Å; W140-V142 PolarHBondContact O-N 3.01Å
141T47.7Very low65.6Low57 Ų5761.4 Ų61.435%0.3532%0.317SS..BIsolated β-bridgetrans-64.8120.1176.847.70000110.2D134 Y135 N143D134-T141 CarbonylContact O-C 3.27Å; D134-T141 WeakPolarHBondContact O-CA 3.27Å; Y135-T141 HydrophobicContact CD1-CG2 3.85Å; Y135-T141 HydrophobicContact CE1-CG2 3.54Å; T141-N143 PolarHBondContact O-N 3.35Å
142V47Very low66.5Low40 Ų4059.5 Ų59.524%0.24230%0.297CS..  trans-84.567.6179.5-167.60000108.5D134 D136 W140 H144D134-V142 PolarHBondContact O-N 3.13Å; D136-V142 VanDerWaalsContact CA-CG2 3.49Å; D136-V142 HydrophobicContact CB-CG2 3.4Å; D136-V142 VanDerWaalsContact CB-CG2 3.4Å; W140-V142 PolarHBondContact O-N 3.01Å; V142-H144 VanDerWaalsContact C-N 3.27Å; V142-H144 WeakPolarHBondContact CG1-NE2 3.4Å; V142-H144 PolarHBondContact O-N 3.16Å
143N50.3Low67.6Low26 Ų2659 Ų5914%0.13929%0.292CS..  trans-78.180.2171.4-82-13.2000109.1D124 A127 T141 A145D124-N143 PolarHBondContact OD1-ND2 3.1Å; A127-N143 HydrophobicContact CB-CB 4.3Å; T141-N143 PolarHBondContact O-N 3.35Å; N143-A145 PolarHBondContact O-N 3.03Å
144H55.7Low69.1Low155 Ų15557.8 Ų57.872%0.71829%0.285SS*.  trans-68.179.1163-72.7-51.4000108.7V142 P146V142-H144 VanDerWaalsContact C-N 3.27Å; V142-H144 WeakPolarHBondContact CG1-NE2 3.4Å; V142-H144 PolarHBondContact O-N 3.16Å; H144-P146 WeakPolarHBondContact O-CD 3.12Å
145A60.9Low70.8Confident18 Ų1853.4 Ų53.415%0.14926%0.262CS..  trans-2392-177.700000113.3A22 I123 N143A22-A145 HydrophobicContact CB-CB 4.1Å; I123-A145 HydrophobicContact CG2-CB 3.68Å; N143-A145 PolarHBondContact O-N 3.03Å
146P80Confident72.7Confident24 Ų2452.7 Ų52.716%0.15626%0.259CS..  trans-57.7148.8-177.8-26.934.7000110H144 T148 S149 L150H144-P146 WeakPolarHBondContact O-CD 3.12Å; P146-T148 PolarHBondContact O-N 3.04Å; P146-T148 VanDerWaalsContact O-N 3.1Å; P146-S149 WeakPolarHBondContact CD-OG 3.29Å; P146-S149 VanDerWaalsContact N-OG 3.11Å; P146-S149 WeakPolarHBondContact O-CA 3.41Å; P146-S149 WeakPolarHBondContact O-CB 3.2Å; P146-S149 PolarHBondContact O-N 2.9Å; P146-S149 PolarHBondContact O-OG 3.18Å; P146-L150 PolarHBondContact O-N 3.18Å
147K87.6Confident74.9Confident40 Ų4048.7 Ų48.717%0.17424%0.238CC..Hα-helixtrans-56.7-33.6-178.4-67.2-178-177.9-174.30111.6D9 I12 L14 L150 L151D9-K147 WeakPolarHBondContact O-CD 3.46Å; D9-K147 PolarHBondContact OD1-N 3.5Å; D9-K147 VanDerWaalsContact OD1-N 3.12Å; D9-K147 PolarHBondContact OD2-N 3.11Å; I12-K147 HydrophobicContact CB-CB 4.07Å; I12-K147 HydrophobicContact CB-CD 4.3Å; I12-K147 HydrophobicContact CD1-CB 4.22Å; I12-K147 HydrophobicContact CG2-CB 4.17Å; I12-K147 PolarHBondContact O-NZ 3.05Å; L14-K147 HydrophobicContact CB-CD 4.5Å; L14-K147 WeakPolarHBondContact O-CD 3.34Å; L14-K147 WeakPolarHBondContact O-CE 3.47Å; L14-K147 PolarHBondContact O-NZ 3.44Å; K147-L150 PolarHBondContact O-N 3.03Å; K147-L151 VanDerWaalsContact O-CB 3.27Å; K147-L151 WeakPolarHBondContact O-CB 3.42Å; K147-L151 PolarHBondContact O-N 2.82Å
148T89.1Confident77.2Confident0 Ų039.5 Ų39.50%020%0.195CC..Hα-helixtrans-64.5-43.3175-50.30000111.6D9 I12 I130 P146 L151 A152 A425D9-T148 VanDerWaalsContact OD1-CB 3.31Å; D9-T148 WeakPolarHBondContact OD1-CB 3.41Å; D9-T148 PolarHBondContact OD1-N 2.84Å; D9-T148 PolarHBondContact OD1-OG1 3.29Å; I12-T148 HydrophobicContact CD1-CG2 4.43Å; I12-T148 WeakPolarHBondContact CD1-OG1 3.4Å; I130-T148 HydrophobicContact CD1-CG2 3.81Å; P146-T148 PolarHBondContact O-N 3.04Å; P146-T148 VanDerWaalsContact O-N 3.1Å; T148-L151 PolarHBondContact O-N 3.29Å; T148-A152 WeakPolarHBondContact O-CB 3.42Å; T148-A152 PolarHBondContact O-N 3.42Å; T148-A425 HydrophobicContact CG2-CB 4.12Å
149S91.4Very high79.4Confident0 Ų031.5 Ų31.50%016%0.16CC..Hα-helixtrans-66.2-41.5177.874.10000111.8P146 A152 A153P146-S149 WeakPolarHBondContact CD-OG 3.29Å; P146-S149 VanDerWaalsContact N-OG 3.11Å; P146-S149 WeakPolarHBondContact O-CA 3.41Å; P146-S149 WeakPolarHBondContact O-CB 3.2Å; P146-S149 PolarHBondContact O-N 2.9Å; P146-S149 PolarHBondContact O-OG 3.18Å; S149-A152 PolarHBondContact O-N 2.89Å; S149-A153 VanDerWaalsContact O-CB 3.31Å; S149-A153 WeakPolarHBondContact O-CB 3.36Å; S149-A153 PolarHBondContact O-N 3.29Å
150L92.8Very high81.8Confident4 Ų427.7 Ų27.72%0.02113%0.133CC..Hα-helixtrans-62.7-46.9175.1173.460.6000110.2L14 L17 A22 V26 P146 K147 A153 I154L14-L150 HydrophobicContact CD1-CD2 4.37Å; L14-L150 HydrophobicContact CD1-CG 4.42Å; L17-L150 HydrophobicContact CD1-CD2 3.8Å; L17-L150 HydrophobicContact CG-CD2 4.34Å; A22-L150 HydrophobicContact CB-CD1 4.03Å; V26-L150 HydrophobicContact CG2-CD1 3.76Å; P146-L150 PolarHBondContact O-N 3.18Å; K147-L150 PolarHBondContact O-N 3.03Å; L150-A153 PolarHBondContact O-N 3.35Å; L150-I154 HydrophobicContact CD1-CD1 3.86Å; L150-I154 HydrophobicContact CD1-CG1 4.1Å; L150-I154 HydrophobicContact CG-CD1 3.92Å; L150-I154 WeakPolarHBondContact O-CB 3.32Å; L150-I154 VanDerWaalsContact O-CG1 3.29Å; L150-I154 WeakPolarHBondContact O-CG1 3.19Å; L150-I154 PolarHBondContact O-N 3.4Å
151L94.3Very high84.3Confident6 Ų618.3 Ų18.33%0.03110%0.098CC..Hα-helixtrans-61.4-45.9178.6-17659.7000111.8I12 L14 K147 T148 A153 I154 F155 A425 L446I12-L151 HydrophobicContact CG2-CD2 4.11Å; L14-L151 HydrophobicContact CD1-CB 3.77Å; L14-L151 HydrophobicContact CD1-CD1 4.05Å; L14-L151 HydrophobicContact CD1-CG 4.41Å; K147-L151 VanDerWaalsContact O-CB 3.27Å; K147-L151 WeakPolarHBondContact O-CB 3.42Å; K147-L151 PolarHBondContact O-N 2.82Å; T148-L151 PolarHBondContact O-N 3.29Å; L151-A153 VanDerWaalsContact C-N 3.33Å; L151-A153 PolarHBondContact O-N 3.33Å; L151-I154 PolarHBondContact O-N 2.88Å; L151-F155 HydrophobicContact CD1-CD2 3.95Å; L151-F155 HydrophobicContact CD1-CE2 3.57Å; L151-F155 HydrophobicContact CD1-CZ 4.39Å; L151-F155 HydrophobicContact CD2-CE2 4.28Å; L151-F155 HydrophobicContact CG-CD2 3.93Å; L151-F155 HydrophobicContact CG-CE2 3.75Å; L151-F155 VanDerWaalsContact O-CD2 3.28Å; L151-F155 WeakPolarHBondContact O-CD2 3.49Å; L151-F155 PolarHBondContact O-N 3.31Å; L151-A425 HydrophobicContact CB-CB 4.27Å; L151-A425 HydrophobicContact CD2-CB 4.17Å; L151-A425 HydrophobicContact CG-CB 4.11Å; L151-L446 HydrophobicContact CD1-CD1 3.87Å; L151-L446 HydrophobicContact CD1-CD2 4.18Å; L151-L446 HydrophobicContact CD2-CD1 4.46Å
152A95.6Very high86.7Confident0 Ų015.6 Ų15.60%08%0.081CC..Hα-helixtrans-61.6-41176.500000111.8F126 T148 S149 F155 F156 A425F126-A152 HydrophobicContact CD2-CB 3.54Å; F126-A152 HydrophobicContact CE2-CB 3.65Å; F126-A152 HydrophobicContact CG-CB 4.1Å; F126-A152 HydrophobicContact CZ-CB 4.29Å; T148-A152 WeakPolarHBondContact O-CB 3.42Å; T148-A152 PolarHBondContact O-N 3.42Å; S149-A152 PolarHBondContact O-N 2.89Å; A152-F155 PolarHBondContact O-N 3.43Å; A152-F156 WeakPolarHBondContact O-CB 3.47Å; A152-F156 PolarHBondContact O-N 2.95Å; A152-A425 HydrophobicContact CB-CB 3.77Å
153A96.8Very high89.1Confident0 Ų013.7 Ų13.70%07%0.069CC..Hα-helixtrans-68.9-36.8177.200000112.8V26 I123 F126 S149 L150 L151 F156 A157V26-A153 HydrophobicContact CG1-CB 4.35Å; V26-A153 HydrophobicContact CG2-CB 4Å; I123-A153 HydrophobicContact CB-CB 4.49Å; I123-A153 HydrophobicContact CG1-CB 3.5Å; F126-A153 HydrophobicContact CD2-CB 4.31Å; F126-A153 HydrophobicContact CE2-CB 4.43Å; S149-A153 VanDerWaalsContact O-CB 3.31Å; S149-A153 WeakPolarHBondContact O-CB 3.36Å; S149-A153 PolarHBondContact O-N 3.29Å; L150-A153 PolarHBondContact O-N 3.35Å; L151-A153 VanDerWaalsContact C-N 3.33Å; L151-A153 PolarHBondContact O-N 3.33Å; A153-F156 PolarHBondContact O-N 3Å; A153-A157 VanDerWaalsContact O-CB 3.3Å; A153-A157 WeakPolarHBondContact O-CB 3.46Å; A153-A157 PolarHBondContact O-N 3.34Å
154I97.3Very high91.2Very high13 Ų1313 Ų137%0.0677%0.066CC..Hα-helixtrans-63.4-45.5172.5-72170.7000110.3T25 V26 V29 L150 L151 F156 A157 A158 L450T25-I154 HydrophobicContact CG2-CD1 4.45Å; V26-I154 HydrophobicContact CG2-CG1 3.87Å; V29-I154 HydrophobicContact CG1-CG2 4.5Å; L150-I154 HydrophobicContact CD1-CD1 3.86Å; L150-I154 HydrophobicContact CD1-CG1 4.1Å; L150-I154 HydrophobicContact CG-CD1 3.92Å; L150-I154 WeakPolarHBondContact O-CB 3.32Å; L150-I154 VanDerWaalsContact O-CG1 3.29Å; L150-I154 WeakPolarHBondContact O-CG1 3.19Å; L150-I154 PolarHBondContact O-N 3.4Å; L151-I154 PolarHBondContact O-N 2.88Å; I154-F156 VanDerWaalsContact C-N 3.33Å; I154-F156 PolarHBondContact O-N 2.94Å; I154-A157 PolarHBondContact O-N 3.45Å; I154-A158 WeakPolarHBondContact O-CB 3.24Å; I154-A158 PolarHBondContact O-N 3.5Å; I154-L450 HydrophobicContact CG2-CD1 3.46Å; I154-L450 VanDerWaalsContact CG2-CD1 3.46Å; I154-L450 HydrophobicContact CG2-CD2 3.71Å; I154-L450 HydrophobicContact CG2-CG 4.25Å
155F97.8Very high93.2Very high1 Ų15.6 Ų5.60%0.0043%0.031CC..Hα-helixtrans-63-40.3176-84-57.7000112.4L151 A152 A158 H159 C421 L424 L428 L446 L449 Y453L151-F155 HydrophobicContact CD1-CD2 3.95Å; L151-F155 HydrophobicContact CD1-CE2 3.57Å; L151-F155 HydrophobicContact CD1-CZ 4.39Å; L151-F155 HydrophobicContact CD2-CE2 4.28Å; L151-F155 HydrophobicContact CG-CD2 3.93Å; L151-F155 HydrophobicContact CG-CE2 3.75Å; L151-F155 VanDerWaalsContact O-CD2 3.28Å; L151-F155 WeakPolarHBondContact O-CD2 3.49Å; L151-F155 PolarHBondContact O-N 3.31Å; A152-F155 PolarHBondContact O-N 3.43Å; F155-A158 CarbonylContact O-C 3.45Å; F155-A158 PolarHBondContact O-N 2.73Å; F155-H159 WeakPolarHBondContact O-CB 3.33Å; F155-H159 PolarHBondContact O-N 3.04Å; F155-C421 HydrophobicContact CB-CB 4.1Å; F155-L424 HydrophobicContact CD1-CD2 4.02Å; F155-L424 HydrophobicContact CD2-CD2 4.07Å; F155-L424 HydrophobicContact CD2-CG 4.46Å; F155-L424 HydrophobicContact CE1-CD2 4.05Å; F155-L424 HydrophobicContact CE2-CD2 4.08Å; F155-L424 HydrophobicContact CE2-CG 4.3Å; F155-L424 HydrophobicContact CG-CD2 4.03Å; F155-L424 HydrophobicContact CZ-CD2 4.06Å; F155-L428 HydrophobicContact CE2-CD1 3.57Å; F155-L428 HydrophobicContact CZ-CD1 3.75Å; F155-L446 HydrophobicContact CE2-CD1 3.77Å; F155-L446 HydrophobicContact CZ-CD1 3.46Å; F155-L446 VanDerWaalsContact CZ-CD1 3.46Å; F155-L449 HydrophobicContact CE1-CD2 3.84Å; F155-L449 HydrophobicContact CE1-CG 4.02Å; F155-L449 HydrophobicContact CZ-CD2 3.95Å; F155-Y453 HydrophobicContact CD1-CD2 4.06Å; F155-Y453 HydrophobicContact CD1-CE2 4.04Å
156F98.4Very high94.9Very high0 Ų04.8 Ų4.80%02%0.024CC..Hα-helixtrans-61.4-51174.2-177.1-92000110.5I118 M122 A152 A153 I154 A158 H159 H162 Y414 S417 A418 C421I118-F156 HydrophobicContact CG2-CE1 4.01Å; I118-F156 HydrophobicContact CG2-CZ 4.31Å; M122-F156 HydrophobicContact CE-CE2 4.43Å; M122-F156 HydrophobicContact CE-CZ 4.37Å; M122-F156 HydrophobicContact CG-CD1 4.04Å; M122-F156 HydrophobicContact CG-CE1 4.09Å; M122-F156 HydrophobicContact CG-CG 4.39Å; M122-F156 HydrophobicContact CG-CZ 4.48Å; A152-F156 WeakPolarHBondContact O-CB 3.47Å; A152-F156 PolarHBondContact O-N 2.95Å; A153-F156 PolarHBondContact O-N 3Å; I154-F156 VanDerWaalsContact C-N 3.33Å; I154-F156 PolarHBondContact O-N 2.94Å; F156-A158 PolarHBondContact O-N 3.33Å; F156-A158 VanDerWaalsContact O-N 3.17Å; F156-H159 PolarHBondContact O-N 3.2Å; F156-H159 VanDerWaalsContact O-N 3.16Å; F156-H162 AromaticContact CD1-CE1 3.96Å; F156-H162 AromaticContact CD2-CE1 3.65Å; F156-H162 AromaticContact CE1-CE1 3.85Å; F156-H162 AromaticContact CE2-CE1 3.55Å; F156-H162 AromaticContact CE2-NE2 3.74Å; F156-H162 AromaticContact CG-CE1 3.87Å; F156-H162 AromaticContact CZ-CE1 3.64Å; F156-H162 PolarHBondContact O-CE1 3.02Å; F156-H162 PolarHBondContact O-ND1 2.81Å; F156-Y414 WeakPolarHBondContact CE2-O 3.32Å; F156-Y414 HydrophobicContact CZ-CD1 4.47Å; F156-Y414 AromaticContact CZ-CE1 3.93Å; F156-Y414 HydrophobicContact CZ-CE1 3.93Å; F156-S417 WeakPolarHBondContact CE2-OG 3.49Å; F156-A418 HydrophobicContact CD2-CB 3.95Å; F156-A418 HydrophobicContact CE2-CB 3.88Å; F156-C421 HydrophobicContact CB-CB 4.33Å; F156-C421 PolarHBondContact N-SG 2.95Å
157A98.3Very high95.8Very high0 Ų03.6 Ų3.60%02%0.017CC..Hα-helixtrans-58.3-30178.500000114.1V26 V29 A30 H115 A153 I154V26-A157 HydrophobicContact CG1-CB 4.02Å; V29-A157 HydrophobicContact CG1-CB 4.21Å; A30-A157 HydrophobicContact CB-CB 4.05Å; H115-A157 PolarHBondContact NE2-O 2.65Å; A153-A157 VanDerWaalsContact O-CB 3.3Å; A153-A157 WeakPolarHBondContact O-CB 3.46Å; A153-A157 PolarHBondContact O-N 3.34Å; I154-A157 PolarHBondContact O-N 3.45Å
158A98.1Very high96.2Very high0 Ų01.7 Ų1.70%01%0.009CC..THydrogen-bonded Turntrans-102.58.1-177.900000113.6V29 I154 F155 F156 P160 L450 Y453 V454 C457V29-A158 HydrophobicContact CG1-CB 3.97Å; I154-A158 WeakPolarHBondContact O-CB 3.24Å; I154-A158 PolarHBondContact O-N 3.5Å; F155-A158 CarbonylContact O-C 3.45Å; F155-A158 PolarHBondContact O-N 2.73Å; F156-A158 PolarHBondContact O-N 3.33Å; F156-A158 VanDerWaalsContact O-N 3.17Å; A158-P160 VanDerWaalsContact O-CD 3.29Å; A158-P160 WeakPolarHBondContact O-CD 3.12Å; A158-L450 HydrophobicContact CB-CD1 3.82Å; A158-Y453 WeakPolarHBondContact O-CB 3.4Å; A158-V454 HydrophobicContact CB-CG2 4.11Å; A158-C457 PolarHBondContact O-SG 2.66Å
159H98.1Very high96.5Very high0 Ų01.7 Ų1.70%01%0.009CC..  trans-75.8121.4-172.8-158.5-71.8000111.7F155 F156 V161 H162 L328 Y420 Y453F155-H159 WeakPolarHBondContact O-CB 3.33Å; F155-H159 PolarHBondContact O-N 3.04Å; F156-H159 PolarHBondContact O-N 3.2Å; F156-H159 VanDerWaalsContact O-N 3.16Å; H159-V161 WeakPolarHBondContact ND1-CB 3.47Å; H159-V161 WeakPolarHBondContact ND1-CG1 3.33Å; H159-V161 PolarHBondContact ND1-N 3.31Å; H159-V161 PolarHBondContact O-N 2.79Å; H159-V161 VanDerWaalsContact O-N 3.1Å; H159-H162 WeakPolarHBondContact O-CB 3.3Å; H159-H162 PolarHBondContact O-N 3.16Å; H159-L328 PolarHBondContact NE2-O 3.26Å; H159-Y420 AromaticContact CD2-CE1 3.93Å; H159-Y420 AromaticContact NE2-CD1 3.74Å; H159-Y420 AromaticContact NE2-CE1 3.54Å; H159-Y453 AromaticContact CD2-CE2 3.84Å
160P97.4Very high96.8Very high0 Ų02.4 Ų2.40%01%0.013CC..G310 helixtrans-64.4-22.5-173.9-21.932.4000115.5A158 H162 T163 P331 L334 Y453 R456 C457A158-P160 VanDerWaalsContact O-CD 3.29Å; A158-P160 WeakPolarHBondContact O-CD 3.12Å; P160-H162 PolarHBondContact O-N 3.35Å; P160-H162 VanDerWaalsContact O-N 3.1Å; P160-T163 WeakPolarHBondContact O-CB 3.31Å; P160-T163 PolarHBondContact O-N 3.36Å; P160-T163 VanDerWaalsContact O-N 3.07Å; P160-T163 PolarHBondContact O-OG1 3.42Å; P160-P331 HydrophobicContact CB-CB 3.95Å; P160-P331 HydrophobicContact CB-CG 4.04Å; P160-P331 HydrophobicContact CG-CB 4.18Å; P160-P331 HydrophobicContact CG-CG 3.7Å; P160-L334 HydrophobicContact CB-CD1 3.98Å; P160-Y453 HydrophobicContact CG-CD1 4.49Å; P160-Y453 HydrophobicContact CG-CG 4.38Å; P160-R456 HydrophobicContact CB-CB 3.94Å; P160-R456 HydrophobicContact CG-CB 3.54Å; P160-C457 WeakPolarHBondContact CA-SG 3.4Å
161V96.8Very high97Very high0 Ų02.3 Ų2.30%01%0.013CC..G310 helixtrans-60-14.9172.386.90000113.9H159 L328 E410 L413H159-V161 WeakPolarHBondContact ND1-CB 3.47Å; H159-V161 WeakPolarHBondContact ND1-CG1 3.33Å; H159-V161 PolarHBondContact ND1-N 3.31Å; H159-V161 PolarHBondContact O-N 2.79Å; H159-V161 VanDerWaalsContact O-N 3.1Å; V161-L328 HydrophobicContact CG1-CD2 4.35Å; V161-E410 HydrophobicContact CG2-CB 4.04Å; V161-E410 WeakPolarHBondContact O-CB 3.35Å; V161-L413 HydrophobicContact CG1-CB 4.42Å; V161-L413 HydrophobicContact CG2-CB 3.82Å; V161-L413 HydrophobicContact CG2-CD1 3.86Å; V161-L413 HydrophobicContact CG2-CG 4.43Å
162H97.8Very high97.1Very high0 Ų02 Ų20%01%0.012CC..G310 helixtrans-79.7-10.8176.8-63.3172.2000112.9F34 H115 F156 H159 P160 E164 S165 V166 Y414 S417F34-H162 HydrophobicContact CZ-CB 3.95Å; H115-H162 AromaticContact CE1-ND1 3.25Å; H115-H162 PolarHBondContact CE1-ND1 3.47Å; H115-H162 VanDerWaalsContact CE1-ND1 3.25Å; F156-H162 AromaticContact CD1-CE1 3.96Å; F156-H162 AromaticContact CD2-CE1 3.65Å; F156-H162 AromaticContact CE1-CE1 3.85Å; F156-H162 AromaticContact CE2-CE1 3.55Å; F156-H162 AromaticContact CE2-NE2 3.74Å; F156-H162 AromaticContact CG-CE1 3.87Å; F156-H162 AromaticContact CZ-CE1 3.64Å; F156-H162 PolarHBondContact O-CE1 3.02Å; F156-H162 PolarHBondContact O-ND1 2.81Å; H159-H162 WeakPolarHBondContact O-CB 3.3Å; H159-H162 PolarHBondContact O-N 3.16Å; P160-H162 PolarHBondContact O-N 3.35Å; P160-H162 VanDerWaalsContact O-N 3.1Å; H162-E164 PolarHBondContact O-N 2.95Å; H162-S165 PolarHBondContact O-N 3.35Å; H162-V166 HydrophobicContact CB-CG2 4.21Å; H162-V166 WeakPolarHBondContact O-CG2 3.41Å; H162-V166 PolarHBondContact O-N 3.45Å; H162-Y414 HydrophobicContact CB-CD2 3.98Å; H162-Y414 HydrophobicContact CB-CE2 3.85Å; H162-Y414 AromaticContact CD2-CD2 3.42Å; H162-Y414 VanDerWaalsContact CD2-CD2 3.42Å; H162-Y414 WeakPolarHBondContact CD2-CD2 3.36Å; H162-Y414 AromaticContact CD2-CE2 3.79Å; H162-Y414 AromaticContact CG-CD2 3.66Å; H162-Y414 AromaticContact CG-CE2 3.59Å; H162-Y414 AromaticContact ND1-CE2 3.9Å; H162-S417 PolarHBondContact NE2-OG 2.96Å
163T96.7Very high97.3Very high0 Ų02 Ų20%01%0.012CC..Hα-helixtrans-61.1-43.6-168.3-50.80000113.1F34 P160 S165 V166 A167 R460 S461F34-T163 HydrophobicContact CE1-CG2 4.34Å; P160-T163 WeakPolarHBondContact O-CB 3.31Å; P160-T163 PolarHBondContact O-N 3.36Å; P160-T163 VanDerWaalsContact O-N 3.07Å; P160-T163 PolarHBondContact O-OG1 3.42Å; T163-S165 VanDerWaalsContact C-N 3.31Å; T163-S165 PolarHBondContact O-N 3Å; T163-V166 PolarHBondContact O-N 2.82Å; T163-A167 HydrophobicContact CG2-CB 4.04Å; T163-A167 VanDerWaalsContact O-CB 3.24Å; T163-A167 WeakPolarHBondContact O-CB 3.39Å; T163-A167 PolarHBondContact O-N 2.8Å; T163-R460 HydrophobicContact CG2-CB 3.79Å; T163-R460 HydrophobicContact CG2-CG 3.46Å; T163-R460 VanDerWaalsContact CG2-CG 3.46Å; T163-S461 WeakPolarHBondContact CG2-OG 3.35Å
164E95.5Very high97.3Very high12 Ų122.7 Ų2.76%0.0562%0.015CC..Hα-helixtrans-56.6-44.4173.2-179-177.117800112H162 V166 G168 E410 R411 W464H162-E164 PolarHBondContact O-N 2.95Å; E164-V166 PolarHBondContact O-N 2.92Å; E164-G168 WeakPolarHBondContact O-CA 3.37Å; E164-G168 PolarHBondContact O-N 3.21Å; E164-E410 HydrophobicContact CB-CB 3.84Å; E164-E410 HydrophobicContact CB-CG 4.46Å; E164-E410 WeakPolarHBondContact OE2-CB 2.99Å; E164-E410 PolarHBondContact OE2-N 3.25Å; E164-R411 HydrophobicContact CG-CB 4.27Å; E164-R411 VanDerWaalsContact OE1-CD 3.23Å; E164-R411 WeakPolarHBondContact OE1-CD 3.22Å; E164-R411 WeakPolarHBondContact OE1-CG 3.45Å; E164-R411 IonicContact OE1-CZ 3.95Å; E164-R411 IonicContact OE1-NE 2.68Å; E164-R411 IonicContact OE1-NH1 2.79Å; E164-R411 PolarHBondContact OE2-N 2.85Å; E164-W464 HydrophobicContact CB-CH2 4.36Å; E164-W464 HydrophobicContact CB-CZ2 3.77Å; E164-W464 HydrophobicContact CG-CH2 3.73Å; E164-W464 HydrophobicContact CG-CZ2 3.63Å
165S96.4Very high97.4Very high0 Ų02 Ų20%01%0.012CC..Hα-helixtrans-69.7-29.7-178.5-62.50000113.6H162 T163 G171 L175H162-S165 PolarHBondContact O-N 3.35Å; T163-S165 VanDerWaalsContact C-N 3.31Å; T163-S165 PolarHBondContact O-N 3Å; S165-G171 CarbonylContact O-C 3.48Å; S165-G171 VanDerWaalsContact O-C 3.25Å; S165-G171 WeakPolarHBondContact O-CA 3.41Å; S165-L175 WeakPolarHBondContact O-CD1 3.44Å
166V97.8Very high97.4Very high0 Ų02.7 Ų2.70%02%0.015CC..Hα-helixtrans-94.6-49.3-176.5-1750000112F34 N111 I112 H115 H162 T163 E164 L175F34-V166 HydrophobicContact CB-CG1 3.66Å; F34-V166 HydrophobicContact CD1-CB 3.85Å; F34-V166 HydrophobicContact CD1-CG1 3.88Å; F34-V166 HydrophobicContact CD1-CG2 4.4Å; F34-V166 HydrophobicContact CD2-CB 4.4Å; F34-V166 HydrophobicContact CD2-CG1 3.98Å; F34-V166 HydrophobicContact CD2-CG2 4.34Å; F34-V166 HydrophobicContact CE1-CB 4.19Å; F34-V166 HydrophobicContact CE1-CG2 4.37Å; F34-V166 HydrophobicContact CE2-CG2 4.28Å; F34-V166 HydrophobicContact CG-CB 4.01Å; F34-V166 HydrophobicContact CG-CG1 3.55Å; F34-V166 HydrophobicContact CG-CG2 4.44Å; F34-V166 HydrophobicContact CZ-CG2 4.32Å; N111-V166 VanDerWaalsContact CB-O 3.31Å; N111-V166 WeakPolarHBondContact CB-O 3.45Å; I112-V166 HydrophobicContact CG1-CG1 4.05Å; H115-V166 HydrophobicContact CB-CG1 4.12Å; H115-V166 HydrophobicContact CB-CG2 3.69Å; H162-V166 HydrophobicContact CB-CG2 4.21Å; H162-V166 WeakPolarHBondContact O-CG2 3.41Å; H162-V166 PolarHBondContact O-N 3.45Å; T163-V166 PolarHBondContact O-N 2.82Å; E164-V166 PolarHBondContact O-N 2.92Å; V166-L175 HydrophobicContact CG2-CD2 4.17Å
167A97.1Very high97.4Very high0 Ų02.8 Ų2.80%02%0.016CC..Hα-helixtrans-78.2-38.9-175.700000112.2H108 T163 W464H108-A167 PolarHBondContact CE1-O 3.48Å; H108-A167 PolarHBondContact ND1-O 2.83Å; T163-A167 HydrophobicContact CG2-CB 4.04Å; T163-A167 VanDerWaalsContact O-CB 3.24Å; T163-A167 WeakPolarHBondContact O-CB 3.39Å; T163-A167 PolarHBondContact O-N 2.8Å; A167-W464 HydrophobicContact CB-CB 3.61Å; A167-W464 HydrophobicContact CB-CG 3.86Å
168G96Very high97.4Very high0 Ų02.8 Ų2.80%02%0.016CC..SBendtrans-74.3131172.900000111.2N111 E164 V170 G171N111-G168 PolarHBondContact ND2-O 2.93Å; N111-G168 VanDerWaalsContact ND2-O 3.13Å; E164-G168 WeakPolarHBondContact O-CA 3.37Å; E164-G168 PolarHBondContact O-N 3.21Å; G168-V170 PolarHBondContact O-N 2.96Å; G168-G171 WeakPolarHBondContact O-CA 3.27Å; G168-G171 PolarHBondContact O-N 3.24Å
169V97.2Very high97.4Very high0 Ų04 Ų40%02%0.022CC..G310 helixtrans-66.9-39.9-174.4-177.20000111.3F42 D46 I50 F92 F107 H108 N111 G171 R172F42-V169 HydrophobicContact CD1-CG2 4.19Å; F42-V169 HydrophobicContact CE1-CG2 4.25Å; D46-V169 WeakPolarHBondContact OD1-CA 3.28Å; D46-V169 WeakPolarHBondContact OD1-CB 3.24Å; D46-V169 PolarHBondContact OD1-N 3.33Å; D46-V169 VanDerWaalsContact OD1-N 3.11Å; D46-V169 PolarHBondContact OD2-N 3.4Å; I50-V169 HydrophobicContact CD1-CB 3.48Å; I50-V169 VanDerWaalsContact CD1-CB 3.48Å; I50-V169 HydrophobicContact CD1-CG1 3.21Å; I50-V169 HydrophobicContact CD1-CG2 4.37Å; F92-V169 HydrophobicContact CD1-CG1 4.44Å; F92-V169 HydrophobicContact CE1-CG1 3.89Å; F107-V169 HydrophobicContact CB-CB 4.5Å; F107-V169 HydrophobicContact CB-CG1 3.6Å; F107-V169 HydrophobicContact CB-CG2 4.01Å; F107-V169 HydrophobicContact CD1-CG1 3.76Å; F107-V169 HydrophobicContact CG-CG1 4.09Å; H108-V169 WeakPolarHBondContact CE1-CG2 3.04Å; N111-V169 WeakPolarHBondContact ND2-CA 3.27Å; N111-V169 PolarHBondContact ND2-O 3.49Å; N111-V169 VanDerWaalsContact ND2-O 3.13Å; V169-G171 PolarHBondContact O-N 2.88Å; V169-G171 VanDerWaalsContact O-N 3.1Å; V169-R172 VanDerWaalsContact O-CB 3.26Å; V169-R172 WeakPolarHBondContact O-CB 3.43Å; V169-R172 PolarHBondContact O-N 3.27Å
170V96.4Very high97.5Very high14 Ų146.3 Ų6.39%0.0853%0.032CC..G310 helixtrans-55.9-24.8173.4-72.30000113.7D45 D46 A49 F70 G168 R172 A173D45-V170 HydrophobicContact CB-CG1 4.14Å; D45-V170 HydrophobicContact CB-CG2 3.82Å; D46-V170 WeakPolarHBondContact OD1-CG1 3.32Å; D46-V170 PolarHBondContact OD1-N 3.07Å; A49-V170 HydrophobicContact CB-CG1 3.32Å; F70-V170 HydrophobicContact CE1-CB 4.22Å; F70-V170 HydrophobicContact CE1-CG1 3.94Å; F70-V170 HydrophobicContact CZ-CB 3.99Å; F70-V170 HydrophobicContact CZ-CG1 3.92Å; G168-V170 PolarHBondContact O-N 2.96Å; V170-R172 PolarHBondContact O-N 3.32Å; V170-A173 PolarHBondContact O-N 3.49Å
171G96.7Very high97.5Very high3 Ų36.7 Ų6.73%0.0313%0.034CC..G310 helixtrans-58.9-14173.600000113.9S165 G168 V169 A173 D174 L175S165-G171 CarbonylContact O-C 3.48Å; S165-G171 VanDerWaalsContact O-C 3.25Å; S165-G171 WeakPolarHBondContact O-CA 3.41Å; G168-G171 WeakPolarHBondContact O-CA 3.27Å; G168-G171 PolarHBondContact O-N 3.24Å; V169-G171 PolarHBondContact O-N 2.88Å; V169-G171 VanDerWaalsContact O-N 3.1Å; G171-A173 PolarHBondContact O-N 2.9Å; G171-D174 WeakPolarHBondContact O-CA 3.3Å; G171-D174 VanDerWaalsContact O-CB 3.31Å; G171-D174 WeakPolarHBondContact O-CB 3.27Å; G171-D174 PolarHBondContact O-N 3.5Å; G171-L175 PolarHBondContact O-N 3.28Å
172R98Very high97.5Very high0 Ų06.8 Ų6.80%03%0.034CC..Hα-helixtrans-52.4-30.9171.6-168175.2-64.2-177.3-3.1113.4T88 T91 F92 N95 F107 N111 L114 V169 V170 D174 L175 L176T88-R172 HydrophobicContact CG2-CB 4.28Å; T88-R172 HydrophobicContact CG2-CG 4.44Å; T91-R172 PolarHBondContact O-NH1 3.32Å; T91-R172 WeakPolarHBondContact OG1-CD 3.41Å; F92-R172 HydrophobicContact CE1-CB 3.73Å; F92-R172 HydrophobicContact CE1-CG 4.22Å; F92-R172 HydrophobicContact CZ-CB 4Å; N95-R172 PolarHBondContact OD1-NH1 3.17Å; N95-R172 PolarHBondContact OD1-NH2 3.29Å; F107-R172 VanDerWaalsContact CA-NH2 3.26Å; F107-R172 PolarHBondContact O-NH2 2.71Å; N111-R172 WeakPolarHBondContact OD1-CB 3.42Å; N111-R172 PolarHBondContact OD1-NE 3.45Å; L114-R172 HydrophobicContact CD1-CG 4.14Å; V169-R172 VanDerWaalsContact O-CB 3.26Å; V169-R172 WeakPolarHBondContact O-CB 3.43Å; V169-R172 PolarHBondContact O-N 3.27Å; V170-R172 PolarHBondContact O-N 3.32Å; R172-D174 VanDerWaalsContact C-N 3.27Å; R172-D174 PolarHBondContact O-N 2.96Å; R172-L175 PolarHBondContact O-N 3.32Å; R172-L176 HydrophobicContact CG-CD1 3.8Å; R172-L176 HydrophobicContact CG-CG 3.99Å; R172-L176 WeakPolarHBondContact O-CB 3.34Å; R172-L176 WeakPolarHBondContact O-CG 3.46Å; R172-L176 PolarHBondContact O-N 3Å
173A97.9Very high97.5Very high0 Ų09.4 Ų9.40%05%0.048CC..Hα-helixtrans-57.9-41.717400000112T88 V170 G171 C177T88-A173 HydrophobicContact CG2-CB 3.98Å; V170-A173 PolarHBondContact O-N 3.49Å; G171-A173 PolarHBondContact O-N 2.9Å; A173-C177 WeakPolarHBondContact O-CB 3.25Å; A173-C177 PolarHBondContact O-N 3.48Å; A173-C177 VanDerWaalsContact O-N 3.11Å
174D97.6Very high97.6Very high13 Ų139.4 Ų9.47%0.075%0.048CC..Hα-helixtrans-69.7-44.5177.5-72.2-67000112G171 R172 C177 A178 K221G171-D174 WeakPolarHBondContact O-CA 3.3Å; G171-D174 VanDerWaalsContact O-CB 3.31Å; G171-D174 WeakPolarHBondContact O-CB 3.27Å; G171-D174 PolarHBondContact O-N 3.5Å; R172-D174 VanDerWaalsContact C-N 3.27Å; R172-D174 PolarHBondContact O-N 2.96Å; D174-C177 PolarHBondContact O-N 3.43Å; D174-A178 VanDerWaalsContact O-CB 3.29Å; D174-A178 WeakPolarHBondContact O-CB 3.44Å; D174-A178 PolarHBondContact O-N 3.32Å; D174-K221 WeakPolarHBondContact OD1-CD 3.44Å; D174-K221 WeakPolarHBondContact OD1-CE 3.25Å; D174-K221 IonicContact OD1-NZ 3.44Å; D174-K221 PolarHBondContact OD1-NZ 3.21Å; D174-K221 IonicContact OD2-NZ 2.74Å; D174-K221 PolarHBondContact OD2-NZ 3.39Å
175L98.6Very high97.6Very high0 Ų09 Ų90%05%0.046CC..Hα-helixtrans-64.4-49.2-179.3-57.7179.2000111.7N111 L114 H115 I118 S165 V166 G171 R172 C177 A178 L179 Y414N111-L175 HydrophobicContact CB-CD1 3.59Å; N111-L175 VanDerWaalsContact O-CD1 3.29Å; N111-L175 WeakPolarHBondContact O-CD1 3.37Å; L114-L175 HydrophobicContact CB-CB 4.09Å; L114-L175 HydrophobicContact CB-CD1 4.12Å; L114-L175 HydrophobicContact CD1-CB 4.28Å; H115-L175 HydrophobicContact CB-CD2 4.2Å; I118-L175 HydrophobicContact CD1-CB 3.92Å; I118-L175 HydrophobicContact CD1-CD2 4.17Å; I118-L175 WeakPolarHBondContact CD1-O 3.3Å; S165-L175 WeakPolarHBondContact O-CD1 3.44Å; V166-L175 HydrophobicContact CG2-CD2 4.17Å; G171-L175 PolarHBondContact O-N 3.28Å; R172-L175 PolarHBondContact O-N 3.32Å; L175-C177 PolarHBondContact O-N 3.44Å; L175-A178 PolarHBondContact O-N 3.2Å; L175-L179 WeakPolarHBondContact O-CB 3.13Å; L175-L179 PolarHBondContact O-N 3Å; L175-Y414 HydrophobicContact CD2-CE1 4.27Å; L175-Y414 HydrophobicContact CD2-CE2 3.67Å; L175-Y414 VanDerWaalsContact CD2-OH 3.29Å; L175-Y414 WeakPolarHBondContact CD2-OH 3.35Å
176L98.6Very high97.5Very high15 Ų1510.4 Ų10.48%0.0795%0.053CC..Hα-helixtrans-64.4-41.5177.7-69173.7000111.7T88 T91 L114 R172 A178 L179 F180 C220T88-L176 HydrophobicContact CG2-CD1 4.43Å; T91-L176 HydrophobicContact CG2-CD1 3.63Å; L114-L176 HydrophobicContact CD1-CD2 3.95Å; L114-L176 HydrophobicContact CD1-CG 4.28Å; L114-L176 HydrophobicContact CD2-CD2 4.08Å; R172-L176 HydrophobicContact CG-CD1 3.8Å; R172-L176 HydrophobicContact CG-CG 3.99Å; R172-L176 WeakPolarHBondContact O-CB 3.34Å; R172-L176 WeakPolarHBondContact O-CG 3.46Å; R172-L176 PolarHBondContact O-N 3Å; L176-A178 VanDerWaalsContact C-N 3.34Å; L176-A178 PolarHBondContact O-N 2.98Å; L176-L179 PolarHBondContact O-N 3.27Å; L176-F180 WeakPolarHBondContact O-CD2 3.41Å; L176-F180 PolarHBondContact O-N 3.22Å; L176-C220 HydrophobicContact CB-CB 3.89Å
177C98.4Very high97.3Very high1 Ų111.2 Ų11.21%0.0076%0.059CC..Hα-helixtrans-57.1-48.6173.7179.80000110.9A173 D174 L175 L179 F180 F181 C220 K221 G224A173-C177 WeakPolarHBondContact O-CB 3.25Å; A173-C177 PolarHBondContact O-N 3.48Å; A173-C177 VanDerWaalsContact O-N 3.11Å; D174-C177 PolarHBondContact O-N 3.43Å; L175-C177 PolarHBondContact O-N 3.44Å; C177-L179 PolarHBondContact O-N 2.75Å; C177-F180 PolarHBondContact O-N 3.31Å; C177-F181 WeakPolarHBondContact O-CB 3.29Å; C177-F181 PolarHBondContact O-N 2.9Å; C177-C220 HydrophobicContact CB-CB 4.29Å; C177-K221 HydrophobicContact CB-CB 3.73Å; C177-G224 VanDerWaalsContact SG-CA 3.57Å; C177-G224 PolarHBondContact SG-N 3.16Å; C177-G224 VanDerWaalsContact SG-N 3.4Å
178A98.4Very high97.1Very high0 Ų011.3 Ų11.30%06%0.059CC..Hα-helixtrans-65.8-38.318000000113.2I118 D174 L175 L176 F181 Q182 Y414 L415I118-A178 HydrophobicContact CD1-CB 4.33Å; I118-A178 HydrophobicContact CG2-CB 4.25Å; D174-A178 VanDerWaalsContact O-CB 3.29Å; D174-A178 WeakPolarHBondContact O-CB 3.44Å; D174-A178 PolarHBondContact O-N 3.32Å; L175-A178 PolarHBondContact O-N 3.2Å; L176-A178 VanDerWaalsContact C-N 3.34Å; L176-A178 PolarHBondContact O-N 2.98Å; A178-F181 WeakPolarHBondContact O-CB 3.24Å; A178-F181 PolarHBondContact O-N 3.24Å; A178-Q182 WeakPolarHBondContact O-CG 3.09Å; A178-Q182 PolarHBondContact O-N 3.09Å; A178-Y414 HydrophobicContact CB-CD1 3.86Å; A178-Y414 HydrophobicContact CB-CE1 3.53Å; A178-L415 HydrophobicContact CB-CD2 3.76Å; A178-L415 HydrophobicContact CB-CG 4.25Å
179L98.6Very high96.8Very high25 Ų2511.5 Ų11.513%0.1316%0.06CC..Hα-helixtrans-60.1-53.9174.4178.162.4000111L114 V117 I118 L121 L175 L176 C177 F181 Q182 L183L114-L179 HydrophobicContact CD2-CD2 3.97Å; V117-L179 HydrophobicContact CG1-CD1 4.04Å; I118-L179 HydrophobicContact CD1-CB 4.26Å; I118-L179 HydrophobicContact CG1-CB 3.96Å; I118-L179 HydrophobicContact CG1-CD1 4.32Å; L121-L179 HydrophobicContact CD1-CD1 3.67Å; L175-L179 WeakPolarHBondContact O-CB 3.13Å; L175-L179 PolarHBondContact O-N 3Å; L176-L179 PolarHBondContact O-N 3.27Å; C177-L179 PolarHBondContact O-N 2.75Å; L179-F181 VanDerWaalsContact C-N 3.32Å; L179-F181 PolarHBondContact O-N 3Å; L179-Q182 PolarHBondContact O-N 3.46Å; L179-L183 HydrophobicContact CD1-CD1 4.16Å; L179-L183 HydrophobicContact CD1-CG 4.39Å; L179-L183 HydrophobicContact CG-CD1 4.14Å; L179-L183 VanDerWaalsContact O-CG 3.3Å; L179-L183 WeakPolarHBondContact O-CG 3.29Å; L179-L183 PolarHBondContact O-N 3.48Å
180F98.7Very high96.3Very high50 Ų5016 Ų1622%0.2198%0.08CC..Hα-helixtrans-67.5-32.9179.8-71.1-57.9000112.7L176 C177 L183 S184 L213 A216 A217L176-F180 WeakPolarHBondContact O-CD2 3.41Å; L176-F180 PolarHBondContact O-N 3.22Å; C177-F180 PolarHBondContact O-N 3.31Å; F180-L183 HydrophobicContact CD1-CD1 4.47Å; F180-L183 PolarHBondContact O-N 2.99Å; F180-S184 WeakPolarHBondContact O-CB 3.39Å; F180-S184 PolarHBondContact O-N 2.92Å; F180-L213 HydrophobicContact CD1-CD2 3.85Å; F180-L213 HydrophobicContact CE1-CD2 4.36Å; F180-A216 HydrophobicContact CB-CB 4.44Å; F180-A216 HydrophobicContact CD1-CB 3.95Å; F180-A216 HydrophobicContact CD2-CB 4.03Å; F180-A216 HydrophobicContact CE1-CB 4.18Å; F180-A216 HydrophobicContact CE2-CB 4.26Å; F180-A216 HydrophobicContact CG-CB 3.89Å; F180-A216 HydrophobicContact CZ-CB 4.33Å; F180-A217 HydrophobicContact CB-CB 3.67Å
181F98.4Very high95.8Very high7 Ų715.5 Ų15.53%0.0318%0.077CC..Hα-helixtrans-57.8-50.6171.6178.9-74.4000111C177 A178 L179 S184 F185 T226 V227 V230 P393 L415C177-F181 WeakPolarHBondContact O-CB 3.29Å; C177-F181 PolarHBondContact O-N 2.9Å; A178-F181 WeakPolarHBondContact O-CB 3.24Å; A178-F181 PolarHBondContact O-N 3.24Å; L179-F181 VanDerWaalsContact C-N 3.32Å; L179-F181 PolarHBondContact O-N 3Å; F181-S184 WeakPolarHBondContact O-CB 3.38Å; F181-S184 PolarHBondContact O-N 3.22Å; F181-F185 PolarHBondContact O-N 2.8Å; F181-T226 WeakPolarHBondContact CE2-OG1 3.44Å; F181-V227 HydrophobicContact CD1-CG2 4.24Å; F181-V227 HydrophobicContact CD2-CB 3.52Å; F181-V227 HydrophobicContact CD2-CG2 4.1Å; F181-V227 HydrophobicContact CE1-CG2 4.24Å; F181-V227 HydrophobicContact CE2-CB 3.55Å; F181-V227 HydrophobicContact CE2-CG2 4.13Å; F181-V227 HydrophobicContact CG-CB 4.03Å; F181-V227 HydrophobicContact CG-CG2 4.14Å; F181-V227 HydrophobicContact CZ-CB 4.08Å; F181-V227 HydrophobicContact CZ-CG2 4.18Å; F181-V227 WeakPolarHBondContact O-CG2 3.1Å; F181-V230 HydrophobicContact CZ-CB 4.38Å; F181-V230 HydrophobicContact CZ-CG2 3.83Å; F181-P393 HydrophobicContact CZ-CG 4.44Å; F181-L415 HydrophobicContact CD1-CD2 4.02Å; F181-L415 HydrophobicContact CD2-CD1 3.93Å; F181-L415 HydrophobicContact CD2-CD2 4.5Å; F181-L415 HydrophobicContact CE1-CD2 4.38Å; F181-L415 HydrophobicContact CE2-CD1 4.27Å; F181-L415 HydrophobicContact CG-CD1 4.27Å; F181-L415 HydrophobicContact CG-CD2 4.11Å
182Q97.3Very high95.1Very high2 Ų216.5 Ų16.51%0.0098%0.081CC..Hα-helixtrans-66.2-43.3179.4-71176.213.200111.9I118 M122 V125 A178 L179 S184 F185 L186I118-Q182 PolarHBondContact O-NE2 3.07Å; I118-Q182 PolarHBondContact O-OE1 2.9Å; M122-Q182 HydrophobicContact CE-CG 3.9Å; M122-Q182 VanDerWaalsContact CG-NE2 3.31Å; M122-Q182 HydrophobicContact SD-CG 4.45Å; V125-Q182 HydrophobicContact CG2-CB 4.4Å; V125-Q182 HydrophobicContact CG2-CG 4.3Å; A178-Q182 WeakPolarHBondContact O-CG 3.09Å; A178-Q182 PolarHBondContact O-N 3.09Å; L179-Q182 PolarHBondContact O-N 3.46Å; Q182-S184 VanDerWaalsContact C-N 3.28Å; Q182-S184 PolarHBondContact O-N 2.93Å; Q182-F185 PolarHBondContact O-N 3.31Å; Q182-L186 WeakPolarHBondContact O-CB 3.37Å; Q182-L186 VanDerWaalsContact O-CG 3.29Å; Q182-L186 WeakPolarHBondContact O-CG 3.38Å; Q182-L186 PolarHBondContact O-N 2.81Å
183L97.8Very high93.7Very high56 Ų5619.1 Ų19.129%0.29310%0.095SC..Hα-helixtrans-62.2-38.4176.8-67.2175.2000111.4L121 L179 F180 L186 T187 L213L121-L183 HydrophobicContact CD1-CD2 4.2Å; L179-L183 HydrophobicContact CD1-CD1 4.16Å; L179-L183 HydrophobicContact CD1-CG 4.39Å; L179-L183 HydrophobicContact CG-CD1 4.14Å; L179-L183 VanDerWaalsContact O-CG 3.3Å; L179-L183 WeakPolarHBondContact O-CG 3.29Å; L179-L183 PolarHBondContact O-N 3.48Å; F180-L183 HydrophobicContact CD1-CD1 4.47Å; F180-L183 PolarHBondContact O-N 2.99Å; L183-L186 PolarHBondContact O-N 2.84Å; L183-T187 WeakPolarHBondContact O-CB 3.32Å; L183-T187 VanDerWaalsContact O-CG2 3.27Å; L183-T187 WeakPolarHBondContact O-CG2 3.29Å; L183-T187 PolarHBondContact O-N 3.2Å; L183-T187 PolarHBondContact O-OG1 3.4Å; L183-L213 HydrophobicContact CB-CD1 4.01Å; L183-L213 HydrophobicContact CB-CD2 4.38Å
184S97.9Very high91.6Very high0 Ų025.1 Ų25.10%012%0.12CC..Hα-helixtrans-61.3-44.8174176.40000111.5F180 F181 Q182 T187 Y188 S210F180-S184 WeakPolarHBondContact O-CB 3.39Å; F180-S184 PolarHBondContact O-N 2.92Å; F181-S184 WeakPolarHBondContact O-CB 3.38Å; F181-S184 PolarHBondContact O-N 3.22Å; Q182-S184 VanDerWaalsContact C-N 3.28Å; Q182-S184 PolarHBondContact O-N 2.93Å; S184-T187 PolarHBondContact O-OG1 3.47Å; S184-T187 VanDerWaalsContact O-OG1 3.05Å; S184-Y188 WeakPolarHBondContact O-CB 3.42Å; S184-Y188 PolarHBondContact O-N 2.96Å; S184-S210 WeakPolarHBondContact CB-O 3.5Å; S184-S210 WeakPolarHBondContact O-CB 3.38Å; S184-S210 PolarHBondContact O-OG 2.86Å; S184-S210 PolarHBondContact OG-O 2.85Å; S184-S210 PolarHBondContact OG-OG 2.99Å; S184-S210 VanDerWaalsContact OG-OG 3.04Å
185F96.6Very high89.3Confident4 Ų428.3 Ų28.32%0.01816%0.156CC..Hα-helixtrans-64.9-47.8175.3174.5-97.4000112.6V125 I128 L129 F181 Q182 T187 Y188 C189 V227 V230 N231 F234V125-F185 HydrophobicContact CG1-CD1 4.08Å; V125-F185 HydrophobicContact CG1-CE1 4Å; V125-F185 HydrophobicContact CG2-CD1 4.21Å; I128-F185 HydrophobicContact CG2-CE1 4.28Å; I128-F185 HydrophobicContact CG2-CZ 4.24Å; L129-F185 HydrophobicContact CD2-CE1 4.39Å; L129-F185 HydrophobicContact CD2-CE2 4.12Å; L129-F185 HydrophobicContact CD2-CZ 3.56Å; L129-F185 HydrophobicContact CG-CE1 4.48Å; L129-F185 HydrophobicContact CG-CZ 4.1Å; F181-F185 PolarHBondContact O-N 2.8Å; Q182-F185 PolarHBondContact O-N 3.31Å; F185-T187 PolarHBondContact O-N 3.33Å; F185-Y188 WeakPolarHBondContact O-CB 3.4Å; F185-Y188 PolarHBondContact O-N 3.18Å; F185-C189 PolarHBondContact O-N 3.16Å; F185-C189 PolarHBondContact O-SG 3.19Å; F185-V227 HydrophobicContact CB-CG2 4.18Å; F185-V230 HydrophobicContact CD2-CG1 4.1Å; F185-V230 HydrophobicContact CE2-CG1 4.27Å; F185-N231 VanDerWaalsContact CD2-OD1 3.26Å; F185-N231 WeakPolarHBondContact CD2-OD1 3.48Å; F185-F234 HydrophobicContact CE2-CB 4.05Å; F185-F234 AromaticContact CE2-CD2 3.85Å; F185-F234 HydrophobicContact CE2-CD2 3.85Å; F185-F234 HydrophobicContact CE2-CE2 4.41Å; F185-F234 AromaticContact CE2-CG 3.91Å; F185-F234 HydrophobicContact CE2-CG 3.91Å; F185-F234 AromaticContact CZ-CD2 3.82Å; F185-F234 HydrophobicContact CZ-CD2 3.82Å; F185-F234 HydrophobicContact CZ-CE2 4.01Å; F185-F234 HydrophobicContact CZ-CG 4.32Å
186L93.6Very high86.9Confident28 Ų2831.6 Ų31.615%0.14717%0.174CC..Hα-helixtrans-64.8-37.6-179.4-68.9173.5000112.2L121 D124 V125 I128 Q182 L183 C189 K190L121-L186 HydrophobicContact CD2-CD1 4.32Å; D124-L186 HydrophobicContact CB-CD2 4.25Å; V125-L186 HydrophobicContact CG2-CD1 4.36Å; V125-L186 HydrophobicContact CG2-CD2 3.95Å; V125-L186 HydrophobicContact CG2-CG 4.1Å; I128-L186 HydrophobicContact CD1-CD2 3.65Å; Q182-L186 WeakPolarHBondContact O-CB 3.37Å; Q182-L186 VanDerWaalsContact O-CG 3.29Å; Q182-L186 WeakPolarHBondContact O-CG 3.38Å; Q182-L186 PolarHBondContact O-N 2.81Å; L183-L186 PolarHBondContact O-N 2.84Å; L186-C189 WeakPolarHBondContact O-CB 3.24Å; L186-C189 PolarHBondContact O-N 2.86Å; L186-K190 PolarHBondContact O-N 3.16Å
187T93.5Very high84.4Confident18 Ų1836.3 Ų36.311%0.1120%0.199CC..Hα-helixtrans-72.1-34174.751.90000112.3L183 S184 F185 C189 K190 W206 V209 L213L183-T187 WeakPolarHBondContact O-CB 3.32Å; L183-T187 VanDerWaalsContact O-CG2 3.27Å; L183-T187 WeakPolarHBondContact O-CG2 3.29Å; L183-T187 PolarHBondContact O-N 3.2Å; L183-T187 PolarHBondContact O-OG1 3.4Å; S184-T187 PolarHBondContact O-OG1 3.47Å; S184-T187 VanDerWaalsContact O-OG1 3.05Å; F185-T187 PolarHBondContact O-N 3.33Å; T187-C189 VanDerWaalsContact C-N 3.31Å; T187-C189 PolarHBondContact O-N 2.84Å; T187-K190 WeakPolarHBondContact O-CB 3.45Å; T187-K190 PolarHBondContact O-N 3.37Å; T187-W206 HydrophobicContact CG2-CZ3 4.4Å; T187-V209 HydrophobicContact CG2-CG1 4.2Å; T187-L213 HydrophobicContact CG2-CD1 3.84Å
188Y93.1Very high82Confident1 Ų146 Ų460%0.00424%0.242CC..Hα-helixtrans-60.5-42.1171.1-175.5-104.2000111.5S184 F185 K190 A191 F192 V207 N231 F234 D235 M275S184-Y188 WeakPolarHBondContact O-CB 3.42Å; S184-Y188 PolarHBondContact O-N 2.96Å; F185-Y188 WeakPolarHBondContact O-CB 3.4Å; F185-Y188 PolarHBondContact O-N 3.18Å; Y188-K190 VanDerWaalsContact C-N 3.25Å; Y188-K190 PolarHBondContact O-N 3.33Å; Y188-A191 WeakPolarHBondContact O-CB 3.38Å; Y188-A191 PolarHBondContact O-N 3.16Å; Y188-F192 HydrophobicContact CD1-CE2 4.05Å; Y188-F192 AromaticContact CE1-CE2 3.67Å; Y188-F192 HydrophobicContact CE1-CE2 3.67Å; Y188-F192 HydrophobicContact CE1-CZ 4Å; Y188-F192 AromaticContact CZ-CE2 3.99Å; Y188-F192 AromaticContact CZ-CZ 3.93Å; Y188-V207 HydrophobicContact CD2-CG2 4.29Å; Y188-V207 HydrophobicContact CE2-CG1 4.4Å; Y188-V207 HydrophobicContact CE2-CG2 4.15Å; Y188-N231 HydrophobicContact CD1-CB 3.87Å; Y188-N231 HydrophobicContact CD2-CB 4.49Å; Y188-N231 HydrophobicContact CE1-CB 3.93Å; Y188-N231 HydrophobicContact CG-CB 4.17Å; Y188-F234 HydrophobicContact CD1-CD1 4.25Å; Y188-F234 HydrophobicContact CE1-CD1 4.09Å; Y188-D235 HydrophobicContact CE1-CB 4.44Å; Y188-D235 WeakPolarHBondContact OH-CB 3.32Å; Y188-D235 VanDerWaalsContact OH-CG 3.28Å; Y188-D235 PolarHBondContact OH-OD2 2.96Å; Y188-M275 HydrophobicContact CD2-SD 4.49Å; Y188-M275 HydrophobicContact CE2-CG 4.45Å; Y188-M275 HydrophobicContact CE2-SD 3.57Å; Y188-M275 VanDerWaalsContact CE2-SD 3.57Å
189C89.3Confident79.7Confident4 Ų451 Ų513%0.02727%0.268CS..Hα-helixtrans-58.1-35.8175.8-68.20000112.8I128 L133 F185 L186 T187 A191 F192I128-C189 HydrophobicContact CD1-CB 4.48Å; L133-C189 HydrophobicContact CD2-CB 3.84Å; F185-C189 PolarHBondContact O-N 3.16Å; F185-C189 PolarHBondContact O-SG 3.19Å; L186-C189 WeakPolarHBondContact O-CB 3.24Å; L186-C189 PolarHBondContact O-N 2.86Å; T187-C189 VanDerWaalsContact C-N 3.31Å; T187-C189 PolarHBondContact O-N 2.84Å; C189-A191 PolarHBondContact O-N 3.39Å; C189-F192 PolarHBondContact O-N 3.4Å
190K86.8Confident77.7Confident96 Ų9651.5 Ų51.542%0.41728%0.28SS..G310 helixtrans-67.3-12.3176-67.2-176.5177.8-175.50114L186 T187 Y188 F192 W206L186-K190 PolarHBondContact O-N 3.16Å; T187-K190 WeakPolarHBondContact O-CB 3.45Å; T187-K190 PolarHBondContact O-N 3.37Å; Y188-K190 VanDerWaalsContact C-N 3.25Å; Y188-K190 PolarHBondContact O-N 3.33Å; K190-F192 PolarHBondContact O-N 3.05Å; K190-F192 VanDerWaalsContact O-N 3.16Å; K190-W206 HydrophobicContact CB-CD2 4.06Å; K190-W206 HydrophobicContact CB-CE3 4.44Å; K190-W206 HydrophobicContact CB-CG 4.19Å; K190-W206 HydrophobicContact CD-CH2 4.23Å; K190-W206 HydrophobicContact CD-CZ2 4.39Å; K190-W206 HydrophobicContact CD-CZ3 4.3Å
191A86.8Confident76.3Confident3 Ų357 Ų573%0.02530%0.299CS..G310 helixtrans-65.2-13.8175.300000113Y188 C189 S203 W206 V207Y188-A191 WeakPolarHBondContact O-CB 3.38Å; Y188-A191 PolarHBondContact O-N 3.16Å; C189-A191 PolarHBondContact O-N 3.39Å; A191-S203 PolarHBondContact O-N 3.19Å; A191-W206 HydrophobicContact CB-CB 3.89Å; A191-V207 HydrophobicContact CB-CG2 4Å
192F81.2Confident75.5Confident24 Ų2458.3 Ų58.311%0.10531%0.305CS..G310 helixtrans-115.731.9-171.1-52.3-78.5000114L133 Y135 Y188 C189 K190 F202 F234 I239L133-F192 HydrophobicContact CD1-CB 3.92Å; L133-F192 HydrophobicContact CD1-CD2 4.39Å; Y135-F192 PolarHBondContact OH-O 3.04Å; Y188-F192 HydrophobicContact CD1-CE2 4.05Å; Y188-F192 AromaticContact CE1-CE2 3.67Å; Y188-F192 HydrophobicContact CE1-CE2 3.67Å; Y188-F192 HydrophobicContact CE1-CZ 4Å; Y188-F192 AromaticContact CZ-CE2 3.99Å; Y188-F192 AromaticContact CZ-CZ 3.93Å; C189-F192 PolarHBondContact O-N 3.4Å; K190-F192 PolarHBondContact O-N 3.05Å; K190-F192 VanDerWaalsContact O-N 3.16Å; F192-F202 HydrophobicContact CD1-CB 4.45Å; F192-F202 HydrophobicContact CE1-CB 4.29Å; F192-F234 HydrophobicContact CE2-CE1 4.42Å; F192-I239 HydrophobicContact CB-CD1 4.28Å; F192-I239 HydrophobicContact CD1-CD1 4.13Å; F192-I239 HydrophobicContact CD1-CG1 4.27Å; F192-I239 HydrophobicContact CD1-CG2 3.99Å; F192-I239 HydrophobicContact CD2-CD1 3.95Å; F192-I239 HydrophobicContact CD2-CG1 4.27Å; F192-I239 HydrophobicContact CE1-CD1 4.44Å; F192-I239 HydrophobicContact CE1-CG1 4.08Å; F192-I239 HydrophobicContact CE1-CG2 3.84Å; F192-I239 HydrophobicContact CE2-CD1 4.29Å; F192-I239 HydrophobicContact CE2-CG1 4.1Å; F192-I239 HydrophobicContact CG-CD1 3.87Å; F192-I239 HydrophobicContact CG-CG1 4.36Å; F192-I239 HydrophobicContact CZ-CG1 3.99Å
193N69.2Low75Confident55 Ų5559.5 Ų59.529%0.29431%0.314SS..  trans-67.3142.7178.9-80.413.3000113.5Y135 G195 N196Y135-N193 HydrophobicContact CE1-CB 4.49Å; Y135-N193 WeakPolarHBondContact CE1-OD1 3.49Å; Y135-N193 PolarHBondContact OH-OD1 3.35Å; N193-G195 PolarHBondContact O-N 3.42Å; N193-N196 PolarHBondContact O-N 3.49Å
194K52.8Low74.6Confident125 Ų12560.5 Ų60.554%0.54332%0.322SS..G310 helixtrans-45.6-21.2-171.2-126.2179.8-169.41690118.1Y135 N196Y135-K194 HydrophobicContact CD2-CB 4.31Å; Y135-K194 HydrophobicContact CD2-CG 4.43Å; Y135-K194 PolarHBondContact O-NZ 2.92Å; K194-N196 PolarHBondContact O-N 2.68Å
195G50.1Low74.3Confident80 Ų8067.8 Ų67.883%0.82536%0.356SS*.G310 helixtrans-69-15.6-178.900000114.8N193N193-G195 PolarHBondContact O-N 3.42Å
196N47.7Very low74.1Confident69 Ų6972 Ų7237%0.36937%0.372SS..G310 helixtrans-109.71.9-177.4-86.6-11.3000114.7N193 K194 K198 D199 G200 R201N193-N196 PolarHBondContact O-N 3.49Å; K194-N196 PolarHBondContact O-N 2.68Å; N196-K198 PolarHBondContact O-N 3.33Å; N196-K198 VanDerWaalsContact O-N 3.11Å; N196-D199 PolarHBondContact O-N 3.39Å; N196-G200 PolarHBondContact O-N 3.07Å; N196-R201 HydrophobicContact CB-CB 4.13Å; N196-R201 WeakPolarHBondContact CB-O 3.39Å; N196-R201 PolarHBondContact ND2-O 2.99Å
197D46.3Very low74.1Confident115 Ų11570.8 Ų70.862%0.61537%0.365SS*.THydrogen-bonded Turntrans-66.6-14.6-169.7-89.8-17.1000114.5
198K47.4Very low74.2Confident205 Ų20573.6 Ų73.689%0.89138%0.382SS*.THydrogen-bonded Turntrans-80.6-17.5177.3-71.6-173.5176.7-178.80114.1N196N196-K198 PolarHBondContact O-N 3.33Å; N196-K198 VanDerWaalsContact O-N 3.11Å
199D50.8Low74.4Confident103 Ų10376.6 Ų76.655%0.55140%0.4SS*.THydrogen-bonded Turntrans-126.62.1-172.9-85.43.8000115.2N196 R201N196-D199 PolarHBondContact O-N 3.39Å; D199-R201 HydrophobicContact CB-CG 3.92Å; D199-R201 PolarHBondContact O-N 3.1Å; D199-R201 IonicContact OD2-CZ 2.75Å; D199-R201 IonicContact OD2-NE 2.65Å; D199-R201 PolarHBondContact OD2-NE 2.64Å; D199-R201 IonicContact OD2-NH2 3.7Å; D199-R201 PolarHBondContact OD2-NH2 2.8Å
200G57Low74.8Confident37 Ų3776.5 Ų76.538%0.38140%0.4SS..THydrogen-bonded Turntrans65.922.1-177.200000114.2N196N196-G200 PolarHBondContact O-N 3.07Å
201R69.3Low75.3Confident164 Ų16473 Ų7362%0.61939%0.385SS*.  trans-83120.4179.6-63.5-175.7-158.1-161.57.7110.3N196 D199N196-R201 HydrophobicContact CB-CB 4.13Å; N196-R201 WeakPolarHBondContact CB-O 3.39Å; N196-R201 PolarHBondContact ND2-O 2.99Å; D199-R201 HydrophobicContact CB-CG 3.92Å; D199-R201 PolarHBondContact O-N 3.1Å; D199-R201 IonicContact OD2-CZ 2.75Å; D199-R201 IonicContact OD2-NE 2.65Å; D199-R201 PolarHBondContact OD2-NE 2.64Å; D199-R201 IonicContact OD2-NH2 3.7Å; D199-R201 PolarHBondContact OD2-NH2 2.8Å
202F81.6Confident75.8Confident35 Ų3576 Ų7615%0.15441%0.41CS..  trans-99153.4171.267.1-84.3000110.4F192 V204 V207 K270 R271F192-F202 HydrophobicContact CD1-CB 4.45Å; F192-F202 HydrophobicContact CE1-CB 4.29Å; F202-V204 HydrophobicContact CD2-CG2 4.34Å; F202-V204 HydrophobicContact CE2-CG2 3.7Å; F202-V204 HydrophobicContact CZ-CG2 4.14Å; F202-V204 PolarHBondContact O-N 3.49Å; F202-V207 HydrophobicContact CD2-CG2 3.91Å; F202-V207 HydrophobicContact CE2-CG2 4.16Å; F202-K270 HydrophobicContact CE1-CB 4.13Å; F202-K270 HydrophobicContact CZ-CB 4.18Å; F202-R271 HydrophobicContact CD1-CG 3.7Å; F202-R271 HydrophobicContact CD2-CG 3.81Å; F202-R271 HydrophobicContact CE1-CG 3.62Å; F202-R271 HydrophobicContact CE2-CG 3.73Å; F202-R271 HydrophobicContact CG-CG 3.8Å; F202-R271 HydrophobicContact CZ-CG 3.64Å
203S87.3Confident76.6Confident28 Ų2876.4 Ų76.420%0.19641%0.414CS..  trans-79.8107.6174.8178.50000111.1A191 Q205 W206 V207A191-S203 PolarHBondContact O-N 3.19Å; S203-Q205 PolarHBondContact O-N 3.2Å; S203-W206 PolarHBondContact O-N 2.93Å; S203-V207 PolarHBondContact O-N 3.19Å
204V89.1Confident78Confident76 Ų7673.8 Ų73.846%0.46140%0.4SS..Hα-helixtrans-59.9-34.3174.3178.80000111.2F202 W206 V207 V208 L274F202-V204 HydrophobicContact CD2-CG2 4.34Å; F202-V204 HydrophobicContact CE2-CG2 3.7Å; F202-V204 HydrophobicContact CZ-CG2 4.14Å; F202-V204 PolarHBondContact O-N 3.49Å; V204-W206 PolarHBondContact O-N 3.49Å; V204-V207 PolarHBondContact O-N 3.1Å; V204-V208 HydrophobicContact CG1-CG2 4.19Å; V204-V208 WeakPolarHBondContact O-CG2 3.35Å; V204-V208 PolarHBondContact O-N 3.04Å; V204-L274 HydrophobicContact CG1-CD2 4.06Å
205Q91.9Very high80.2Confident153 Ų15368.7 Ų68.772%0.71538%0.383SS*.Hα-helixtrans-58.3-47.1178.4-68.2178.2-17.800111.6S203 V207 V208 V209S203-Q205 PolarHBondContact O-N 3.2Å; Q205-V207 VanDerWaalsContact C-N 3.33Å; Q205-V207 PolarHBondContact O-N 3.25Å; Q205-V208 PolarHBondContact O-N 2.93Å; Q205-V209 WeakPolarHBondContact O-CG2 3.32Å; Q205-V209 PolarHBondContact O-N 3.38Å
206W92.4Very high82.5Confident94 Ų9465.8 Ų65.836%0.35635%0.35SS..Hα-helixtrans-66.5-34177.9-73.4124.3000112.5T187 K190 A191 S203 V204 V209 S210T187-W206 HydrophobicContact CG2-CZ3 4.4Å; K190-W206 HydrophobicContact CB-CD2 4.06Å; K190-W206 HydrophobicContact CB-CE3 4.44Å; K190-W206 HydrophobicContact CB-CG 4.19Å; K190-W206 HydrophobicContact CD-CH2 4.23Å; K190-W206 HydrophobicContact CD-CZ2 4.39Å; K190-W206 HydrophobicContact CD-CZ3 4.3Å; A191-W206 HydrophobicContact CB-CB 3.89Å; S203-W206 PolarHBondContact O-N 2.93Å; V204-W206 PolarHBondContact O-N 3.49Å; W206-V209 HydrophobicContact CE3-CB 4.5Å; W206-V209 PolarHBondContact O-N 3.1Å; W206-S210 WeakPolarHBondContact O-CB 3.44Å; W206-S210 PolarHBondContact O-N 3.24Å
207V93.5Very high84.9Confident1 Ų162.5 Ų62.51%0.00633%0.333CS..Hα-helixtrans-66.4-41.1173.3-177.40000111.4Y188 A191 F202 S203 V204 Q205 S210 L211 L274 M275Y188-V207 HydrophobicContact CD2-CG2 4.29Å; Y188-V207 HydrophobicContact CE2-CG1 4.4Å; Y188-V207 HydrophobicContact CE2-CG2 4.15Å; A191-V207 HydrophobicContact CB-CG2 4Å; F202-V207 HydrophobicContact CD2-CG2 3.91Å; F202-V207 HydrophobicContact CE2-CG2 4.16Å; S203-V207 PolarHBondContact O-N 3.19Å; V204-V207 PolarHBondContact O-N 3.1Å; Q205-V207 VanDerWaalsContact C-N 3.33Å; Q205-V207 PolarHBondContact O-N 3.25Å; V207-S210 WeakPolarHBondContact O-CB 3.41Å; V207-S210 PolarHBondContact O-N 2.99Å; V207-L211 HydrophobicContact CG1-CD1 4.43Å; V207-L211 WeakPolarHBondContact O-CG 3.44Å; V207-L211 PolarHBondContact O-N 3.26Å; V207-L274 HydrophobicContact CB-CD2 3.95Å; V207-L274 HydrophobicContact CG1-CD2 3.53Å; V207-L274 HydrophobicContact CG1-CG 4.09Å; V207-M275 HydrophobicContact CG1-CG 4.43Å
208V95.2Very high87.3Confident78 Ų7857.5 Ų57.547%0.47331%0.306SS..Hα-helixtrans-65.3-41.6175.9172.30000111.5V204 Q205 S210 L211 A212V204-V208 HydrophobicContact CG1-CG2 4.19Å; V204-V208 WeakPolarHBondContact O-CG2 3.35Å; V204-V208 PolarHBondContact O-N 3.04Å; Q205-V208 PolarHBondContact O-N 2.93Å; V208-S210 VanDerWaalsContact C-N 3.33Å; V208-S210 PolarHBondContact O-N 3.38Å; V208-L211 PolarHBondContact O-N 3.25Å; V208-A212 PolarHBondContact O-N 2.93Å
209V96.7Very high89.6Confident63 Ų6350 Ų5038%0.38228%0.275SS..Hα-helixtrans-60.9-43.5173.5171.30000110.8T187 Q205 W206 L211 A212 L213T187-V209 HydrophobicContact CG2-CG1 4.2Å; Q205-V209 WeakPolarHBondContact O-CG2 3.32Å; Q205-V209 PolarHBondContact O-N 3.38Å; W206-V209 HydrophobicContact CE3-CB 4.5Å; W206-V209 PolarHBondContact O-N 3.1Å; V209-L211 VanDerWaalsContact C-N 3.34Å; V209-L211 PolarHBondContact O-N 3.49Å; V209-A212 PolarHBondContact O-N 3.4Å; V209-L213 HydrophobicContact CG1-CD1 4.06Å; V209-L213 WeakPolarHBondContact O-CG 3.45Å; V209-L213 PolarHBondContact O-N 3.26Å
210S96.9Very high91.9Very high2 Ų245.1 Ų45.11%0.01425%0.249CC..Hα-helixtrans-59.9-42.1175.1178.40000112.3S184 W206 V207 V208 L213 C214 N231S184-S210 WeakPolarHBondContact CB-O 3.5Å; S184-S210 WeakPolarHBondContact O-CB 3.38Å; S184-S210 PolarHBondContact O-OG 2.86Å; S184-S210 PolarHBondContact OG-O 2.85Å; S184-S210 PolarHBondContact OG-OG 2.99Å; S184-S210 VanDerWaalsContact OG-OG 3.04Å; W206-S210 WeakPolarHBondContact O-CB 3.44Å; W206-S210 PolarHBondContact O-N 3.24Å; V207-S210 WeakPolarHBondContact O-CB 3.41Å; V207-S210 PolarHBondContact O-N 2.99Å; V208-S210 VanDerWaalsContact C-N 3.33Å; V208-S210 PolarHBondContact O-N 3.38Å; S210-L213 PolarHBondContact O-N 3.1Å; S210-C214 WeakPolarHBondContact O-CB 3.25Å; S210-C214 PolarHBondContact O-N 2.78Å; S210-N231 PolarHBondContact OG-ND2 3.43Å
211L97.9Very high93.6Very high22 Ų2243.8 Ų43.812%0.11523%0.233CC..Hα-helixtrans-64.8-40.4174.4-73.9172.3000112.5V207 V208 V209 L213 C214 G215 L228 L274V207-L211 HydrophobicContact CG1-CD1 4.43Å; V207-L211 WeakPolarHBondContact O-CG 3.44Å; V207-L211 PolarHBondContact O-N 3.26Å; V208-L211 PolarHBondContact O-N 3.25Å; V209-L211 VanDerWaalsContact C-N 3.34Å; V209-L211 PolarHBondContact O-N 3.49Å; L211-L213 VanDerWaalsContact C-N 3.35Å; L211-L213 PolarHBondContact O-N 3.24Å; L211-C214 WeakPolarHBondContact O-CB 3.32Å; L211-C214 PolarHBondContact O-N 3.26Å; L211-G215 PolarHBondContact O-N 2.81Å; L211-L228 HydrophobicContact CD2-CD2 3.73Å; L211-L274 HydrophobicContact CD1-CG 4.3Å
212A97.9Very high94.7Very high67 Ų6739.1 Ų39.155%0.55422%0.218SC*.Hα-helixtrans-63.1-41.6175.700000111.8V208 V209 G215 A216V208-A212 PolarHBondContact O-N 2.93Å; V209-A212 PolarHBondContact O-N 3.4Å; A212-G215 WeakPolarHBondContact O-CA 3.18Å; A212-G215 PolarHBondContact O-N 2.92Å; A212-G215 VanDerWaalsContact O-N 3.16Å; A212-A216 PolarHBondContact O-N 3.28Å
213L98.4Very high95.2Very high33 Ų3338.3 Ų38.317%0.17322%0.215CC..Hα-helixtrans-67.2-37.1174.7-70.5166.1000112.1F180 L183 T187 V209 S210 L211 G215 A216 A217F180-L213 HydrophobicContact CD1-CD2 3.85Å; F180-L213 HydrophobicContact CE1-CD2 4.36Å; L183-L213 HydrophobicContact CB-CD1 4.01Å; L183-L213 HydrophobicContact CB-CD2 4.38Å; T187-L213 HydrophobicContact CG2-CD1 3.84Å; V209-L213 HydrophobicContact CG1-CD1 4.06Å; V209-L213 WeakPolarHBondContact O-CG 3.45Å; V209-L213 PolarHBondContact O-N 3.26Å; S210-L213 PolarHBondContact O-N 3.1Å; L211-L213 VanDerWaalsContact C-N 3.35Å; L211-L213 PolarHBondContact O-N 3.24Å; L213-G215 VanDerWaalsContact C-N 3.28Å; L213-G215 PolarHBondContact O-N 2.79Å; L213-A216 PolarHBondContact O-N 2.9Å; L213-A217 PolarHBondContact O-N 2.95Å
214C98.3Very high95.6Very high0 Ų037 Ų370%021%0.206CC..Hα-helixtrans-59.7-41.3169.4179.40000110.9S210 L211 A217 M218 V227 L228 M282S210-C214 WeakPolarHBondContact O-CB 3.25Å; S210-C214 PolarHBondContact O-N 2.78Å; L211-C214 WeakPolarHBondContact O-CB 3.32Å; L211-C214 PolarHBondContact O-N 3.26Å; C214-A217 WeakPolarHBondContact O-CB 3.15Å; C214-A217 PolarHBondContact O-N 2.88Å; C214-M218 PolarHBondContact O-N 2.89Å; C214-V227 HydrophobicContact CB-CG1 3.7Å; C214-V227 WeakPolarHBondContact SG-CG1 3.46Å; C214-L228 HydrophobicContact CB-CD2 4.35Å; C214-M282 HydrophobicContact CB-CE 4.2Å; C214-M282 VanDerWaalsContact SG-CE 3.55Å
215G97.9Very high95.9Very high18 Ų1835 Ų3519%0.18619%0.192CC..Hα-helixtrans-57.5-48.4172.200000112.5L211 A212 L213 A217 M218 L219 M282L211-G215 PolarHBondContact O-N 2.81Å; A212-G215 WeakPolarHBondContact O-CA 3.18Å; A212-G215 PolarHBondContact O-N 2.92Å; A212-G215 VanDerWaalsContact O-N 3.16Å; L213-G215 VanDerWaalsContact C-N 3.28Å; L213-G215 PolarHBondContact O-N 2.79Å; G215-A217 PolarHBondContact O-N 3.28Å; G215-M218 WeakPolarHBondContact O-CB 3.43Å; G215-M218 PolarHBondContact O-N 3.36Å; G215-L219 WeakPolarHBondContact O-CG 3.47Å; G215-L219 PolarHBondContact O-N 3.21Å; G215-M282 VanDerWaalsContact CA-CE 3.41Å
216A98.3Very high96.1Very high18 Ų1828.2 Ų28.215%0.14916%0.161CC..Hα-helixtrans-60.6-42.7175.200000112.1L87 F180 A212 L213 M218 L219 C220L87-A216 HydrophobicContact CD1-CB 4.04Å; F180-A216 HydrophobicContact CB-CB 4.44Å; F180-A216 HydrophobicContact CD1-CB 3.95Å; F180-A216 HydrophobicContact CD2-CB 4.03Å; F180-A216 HydrophobicContact CE1-CB 4.18Å; F180-A216 HydrophobicContact CE2-CB 4.26Å; F180-A216 HydrophobicContact CG-CB 3.89Å; F180-A216 HydrophobicContact CZ-CB 4.33Å; A212-A216 PolarHBondContact O-N 3.28Å; L213-A216 PolarHBondContact O-N 2.9Å; A216-M218 PolarHBondContact O-N 2.99Å; A216-L219 PolarHBondContact O-N 2.91Å; A216-C220 PolarHBondContact O-N 3.44Å; A216-C220 VanDerWaalsContact O-N 3.15Å; A216-C220 PolarHBondContact O-SG 3.34Å
217A98.2Very high96.4Very high0 Ų023.8 Ų23.80%014%0.144CC..Hα-helixtrans-58.7-47174.900000111.1F180 L213 C214 G215 L219 C220 K221F180-A217 HydrophobicContact CB-CB 3.67Å; L213-A217 PolarHBondContact O-N 2.95Å; C214-A217 WeakPolarHBondContact O-CB 3.15Å; C214-A217 PolarHBondContact O-N 2.88Å; G215-A217 PolarHBondContact O-N 3.28Å; A217-L219 VanDerWaalsContact C-N 3.33Å; A217-L219 PolarHBondContact O-N 3.13Å; A217-C220 WeakPolarHBondContact O-CA 3.47Å; A217-C220 WeakPolarHBondContact O-CB 3.39Å; A217-C220 PolarHBondContact O-N 2.81Å; A217-K221 PolarHBondContact O-N 2.84Å
218M96.3Very high96.5Very high11 Ų1124.8 Ų24.85%0.05415%0.149CC..Hα-helixtrans-60.8-37.1176.8-92.3-166.862.700113.9C214 G215 A216 C220 K221 I225 M282 L283 R286C214-M218 PolarHBondContact O-N 2.89Å; G215-M218 WeakPolarHBondContact O-CB 3.43Å; G215-M218 PolarHBondContact O-N 3.36Å; A216-M218 PolarHBondContact O-N 2.99Å; M218-C220 PolarHBondContact O-N 3.27Å; M218-K221 VanDerWaalsContact CA-O 3.29Å; M218-K221 WeakPolarHBondContact CA-O 3.18Å; M218-K221 CarbonylContact O-C 3.44Å; M218-I225 HydrophobicContact CG-CB 3.94Å; M218-I225 HydrophobicContact SD-CB 3.69Å; M218-I225 HydrophobicContact SD-CD1 3.62Å; M218-I225 HydrophobicContact SD-CG1 4.02Å; M218-M282 HydrophobicContact CB-CE 4.28Å; M218-M282 HydrophobicContact CG-CE 4.01Å; M218-M282 HydrophobicContact SD-CB 4.08Å; M218-M282 HydrophobicContact SD-CE 3.37Å; M218-M282 WeakPolarHBondContact SD-CE 3.45Å; M218-L283 HydrophobicContact CE-CD2 4.42Å; M218-R286 HydrophobicContact CE-CB 4.16Å; M218-R286 VanDerWaalsContact CE-CD 3.42Å; M218-R286 HydrophobicContact CE-CG 4.42Å; M218-R286 PolarHBondContact O-NH1 3.39Å
219L97.4Very high96.5Very high47 Ų4722.6 Ų22.625%0.24614%0.143CC..Hα-helixtrans-73.6-13.2175.8-67.7172.9000112.8W66 Y84 R85 P86 L87 G215 A216 A217W66-L219 HydrophobicContact CZ3-CD1 4.29Å; W66-L219 HydrophobicContact CZ3-CD2 4.4Å; Y84-L219 HydrophobicContact CD1-CD2 4.5Å; Y84-L219 HydrophobicContact CE1-CD2 3.78Å; R85-L219 CarbonylContact C-O 3.6Å; R85-L219 WeakPolarHBondContact CA-O 3.43Å; P86-L219 VanDerWaalsContact CD-O 3.3Å; P86-L219 WeakPolarHBondContact CD-O 3.44Å; P86-L219 HydrophobicContact CG-CB 4.25Å; P86-L219 HydrophobicContact CG-CD2 3.77Å; L87-L219 HydrophobicContact CB-CB 4.26Å; L87-L219 HydrophobicContact CD1-CB 3.71Å; L87-L219 HydrophobicContact CD1-CD1 4.01Å; L87-L219 HydrophobicContact CG-CB 3.71Å; L87-L219 HydrophobicContact CG-CD1 4.16Å; L87-L219 PolarHBondContact N-O 3.16Å; G215-L219 WeakPolarHBondContact O-CG 3.47Å; G215-L219 PolarHBondContact O-N 3.21Å; A216-L219 PolarHBondContact O-N 2.91Å; A217-L219 VanDerWaalsContact C-N 3.33Å; A217-L219 PolarHBondContact O-N 3.13Å
220C97.6Very high96.5Very high0 Ų019.7 Ų19.70%013%0.125CC..Hα-helixtrans-90.7-44.2169.2-59.30000111.3R85 T88 L176 C177 A216 A217 M218R85-C220 WeakPolarHBondContact CB-O 3.24Å; R85-C220 VanDerWaalsContact CD-O 3.29Å; R85-C220 WeakPolarHBondContact CD-O 3.24Å; R85-C220 VanDerWaalsContact CG-O 3.24Å; R85-C220 WeakPolarHBondContact CG-O 3.49Å; T88-C220 VanDerWaalsContact OG1-CA 3.32Å; T88-C220 WeakPolarHBondContact OG1-CA 3.41Å; T88-C220 PolarHBondContact OG1-O 3.4Å; T88-C220 VanDerWaalsContact OG1-O 3.09Å; L176-C220 HydrophobicContact CB-CB 3.89Å; C177-C220 HydrophobicContact CB-CB 4.29Å; A216-C220 PolarHBondContact O-N 3.44Å; A216-C220 VanDerWaalsContact O-N 3.15Å; A216-C220 PolarHBondContact O-SG 3.34Å; A217-C220 WeakPolarHBondContact O-CA 3.47Å; A217-C220 WeakPolarHBondContact O-CB 3.39Å; A217-C220 PolarHBondContact O-N 2.81Å; M218-C220 PolarHBondContact O-N 3.27Å
221K94.6Very high96.4Very high10 Ų1019.6 Ų19.64%0.04313%0.125CC..  trans-159.3143.1175.5-163.4167-175.9173.30111.5D174 C177 A217 M218 Q223 G224D174-K221 WeakPolarHBondContact OD1-CD 3.44Å; D174-K221 WeakPolarHBondContact OD1-CE 3.25Å; D174-K221 IonicContact OD1-NZ 3.44Å; D174-K221 PolarHBondContact OD1-NZ 3.21Å; D174-K221 IonicContact OD2-NZ 2.74Å; D174-K221 PolarHBondContact OD2-NZ 3.39Å; C177-K221 HydrophobicContact CB-CB 3.73Å; A217-K221 PolarHBondContact O-N 2.84Å; M218-K221 VanDerWaalsContact CA-O 3.29Å; M218-K221 WeakPolarHBondContact CA-O 3.18Å; M218-K221 CarbonylContact O-C 3.44Å; K221-Q223 PolarHBondContact O-N 2.82Å; K221-Q223 VanDerWaalsContact O-N 3.08Å; K221-G224 PolarHBondContact O-N 2.9Å
222E90.5Very high96.1Very high66 Ų6619.8 Ų19.831%0.30813%0.129SC..G310 helixtrans-49.1-35.2178.850.4-76.4174.200114.7R85 G224 I225 R286R85-E222 IonicContact CZ-OE1 2.69Å; R85-E222 IonicContact CZ-OE2 2.73Å; R85-E222 IonicContact NE-OE2 2.78Å; R85-E222 PolarHBondContact NE-OE2 3.32Å; R85-E222 IonicContact NH2-OE1 2.99Å; R85-E222 PolarHBondContact NH2-OE1 3.18Å; R85-E222 IonicContact NH2-OE2 3.45Å; E222-G224 PolarHBondContact O-N 3.48Å; E222-I225 WeakPolarHBondContact O-CG2 3.4Å; E222-I225 PolarHBondContact O-N 2.99Å; E222-R286 IonicContact OE2-NH2 3.32Å; E222-R286 PolarHBondContact OE2-NH2 3.45Å
223Q92.3Very high95.8Very high18 Ų1817.6 Ų17.68%0.08411%0.111CC..G310 helixtrans-57.1-22178.3-74-73.610.300113.6K221 I225 T226 P393K221-Q223 PolarHBondContact O-N 2.82Å; K221-Q223 VanDerWaalsContact O-N 3.08Å; Q223-I225 PolarHBondContact O-N 3.44Å; Q223-I225 VanDerWaalsContact O-N 3.12Å; Q223-T226 WeakPolarHBondContact O-CB 3.39Å; Q223-T226 WeakPolarHBondContact O-CG2 3.31Å; Q223-T226 PolarHBondContact O-N 3.47Å; Q223-T226 VanDerWaalsContact O-N 3.09Å; Q223-T226 PolarHBondContact O-OG1 3.37Å; Q223-P393 VanDerWaalsContact CD-O 3.24Å; Q223-P393 PolarHBondContact NE2-O 3.05Å; Q223-P393 PolarHBondContact OE1-O 3.45Å
224G95.8Very high95.3Very high0 Ų016 Ų160%010%0.103CC..G310 helixtrans-56.9-29.1-17800000114.7C177 K221 E222 T226 V227C177-G224 VanDerWaalsContact SG-CA 3.57Å; C177-G224 PolarHBondContact SG-N 3.16Å; C177-G224 VanDerWaalsContact SG-N 3.4Å; K221-G224 PolarHBondContact O-N 2.9Å; E222-G224 PolarHBondContact O-N 3.48Å; G224-T226 PolarHBondContact O-N 3.49Å; G224-T226 VanDerWaalsContact O-N 3.14Å; G224-V227 WeakPolarHBondContact O-CG1 3.43Å; G224-V227 PolarHBondContact O-N 2.85Å
225I96Very high94.8Very high34 Ų3416 Ų1617%0.17410%0.103CC..G310 helixtrans-61.3-25.1179.4-166.761.7000112.9M218 E222 Q223 V227 L228 M282 L283M218-I225 HydrophobicContact CG-CB 3.94Å; M218-I225 HydrophobicContact SD-CB 3.69Å; M218-I225 HydrophobicContact SD-CD1 3.62Å; M218-I225 HydrophobicContact SD-CG1 4.02Å; E222-I225 WeakPolarHBondContact O-CG2 3.4Å; E222-I225 PolarHBondContact O-N 2.99Å; Q223-I225 PolarHBondContact O-N 3.44Å; Q223-I225 VanDerWaalsContact O-N 3.12Å; I225-V227 PolarHBondContact O-N 3.45Å; I225-V227 VanDerWaalsContact O-N 3.11Å; I225-L228 HydrophobicContact CD1-CD1 3.54Å; I225-L228 HydrophobicContact CD1-CG 4.25Å; I225-L228 HydrophobicContact CG1-CD1 4.45Å; I225-L228 PolarHBondContact O-N 3.42Å; I225-L228 VanDerWaalsContact O-N 3.1Å; I225-M282 HydrophobicContact CD1-CE 4.1Å; I225-L283 HydrophobicContact CG1-CD2 4.48Å
226T96.5Very high94.1Very high11 Ų1117.1 Ų17.17%0.06711%0.106CC..G310 helixtrans-64.8-16.6-176.462.40000112.7F181 Q223 G224 L228 G229 V230 V392 P396F181-T226 WeakPolarHBondContact CE2-OG1 3.44Å; Q223-T226 WeakPolarHBondContact O-CB 3.39Å; Q223-T226 WeakPolarHBondContact O-CG2 3.31Å; Q223-T226 PolarHBondContact O-N 3.47Å; Q223-T226 VanDerWaalsContact O-N 3.09Å; Q223-T226 PolarHBondContact O-OG1 3.37Å; G224-T226 PolarHBondContact O-N 3.49Å; G224-T226 VanDerWaalsContact O-N 3.14Å; T226-L228 PolarHBondContact O-N 2.91Å; T226-G229 PolarHBondContact O-N 3.37Å; T226-V230 PolarHBondContact O-N 3.21Å; T226-V392 WeakPolarHBondContact CG2-O 3.3Å; T226-P396 HydrophobicContact CG2-CG 3.61Å
227V97.6Very high93.1Very high0 Ų017.9 Ų17.90%011%0.108CC..Hα-helixtrans-59.8-31.1173.373.80000111.9F181 F185 C214 G224 I225 G229 V230 N231F181-V227 HydrophobicContact CD1-CG2 4.24Å; F181-V227 HydrophobicContact CD2-CB 3.52Å; F181-V227 HydrophobicContact CD2-CG2 4.1Å; F181-V227 HydrophobicContact CE1-CG2 4.24Å; F181-V227 HydrophobicContact CE2-CB 3.55Å; F181-V227 HydrophobicContact CE2-CG2 4.13Å; F181-V227 HydrophobicContact CG-CB 4.03Å; F181-V227 HydrophobicContact CG-CG2 4.14Å; F181-V227 HydrophobicContact CZ-CB 4.08Å; F181-V227 HydrophobicContact CZ-CG2 4.18Å; F181-V227 WeakPolarHBondContact O-CG2 3.1Å; F185-V227 HydrophobicContact CB-CG2 4.18Å; C214-V227 HydrophobicContact CB-CG1 3.7Å; C214-V227 WeakPolarHBondContact SG-CG1 3.46Å; G224-V227 WeakPolarHBondContact O-CG1 3.43Å; G224-V227 PolarHBondContact O-N 2.85Å; I225-V227 PolarHBondContact O-N 3.45Å; I225-V227 VanDerWaalsContact O-N 3.11Å; V227-G229 VanDerWaalsContact C-N 3.29Å; V227-G229 PolarHBondContact O-N 2.99Å; V227-V230 PolarHBondContact O-N 3.32Å; V227-N231 WeakPolarHBondContact O-CB 3.31Å; V227-N231 VanDerWaalsContact O-CG 3.26Å; V227-N231 PolarHBondContact O-N 3.25Å
228L96.9Very high92.2Very high22 Ų2219.5 Ų19.512%0.11512%0.116CC..Hα-helixtrans-64.9-36.5176.5-57.9-175.1000111.5L211 C214 I225 T226 A232 M275L211-L228 HydrophobicContact CD2-CD2 3.73Å; C214-L228 HydrophobicContact CB-CD2 4.35Å; I225-L228 HydrophobicContact CD1-CD1 3.54Å; I225-L228 HydrophobicContact CD1-CG 4.25Å; I225-L228 HydrophobicContact CG1-CD1 4.45Å; I225-L228 PolarHBondContact O-N 3.42Å; I225-L228 VanDerWaalsContact O-N 3.1Å; T226-L228 PolarHBondContact O-N 2.91Å; L228-A232 VanDerWaalsContact O-CB 3.26Å; L228-A232 WeakPolarHBondContact O-CB 3.31Å; L228-A232 PolarHBondContact O-N 3.3Å; L228-M275 HydrophobicContact CB-CE 4.22Å; L228-M275 HydrophobicContact CD2-CE 4.33Å; L228-M275 WeakPolarHBondContact O-CE 3.23Å
229G95.2Very high91.3Very high33 Ų3321.5 Ų21.534%0.3413%0.126SC..Hα-helixtrans-66.5-40.217400000112T226 V227 A232 A233T226-G229 PolarHBondContact O-N 3.37Å; V227-G229 VanDerWaalsContact C-N 3.29Å; V227-G229 PolarHBondContact O-N 2.99Å; G229-A232 PolarHBondContact O-N 3.33Å; G229-A233 WeakPolarHBondContact O-CB 3.26Å; G229-A233 PolarHBondContact O-N 3.5Å
230V95.5Very high90.2Very high1 Ų120.3 Ų20.31%0.00612%0.121CC..Hα-helixtrans-67-44.8175.4179.60000111.5F181 F185 T226 V227 A232 A233 F234 V388 L389 V392F181-V230 HydrophobicContact CZ-CB 4.38Å; F181-V230 HydrophobicContact CZ-CG2 3.83Å; F185-V230 HydrophobicContact CD2-CG1 4.1Å; F185-V230 HydrophobicContact CE2-CG1 4.27Å; T226-V230 PolarHBondContact O-N 3.21Å; V227-V230 PolarHBondContact O-N 3.32Å; V230-A232 VanDerWaalsContact C-N 3.33Å; V230-A232 PolarHBondContact O-N 3.49Å; V230-A233 PolarHBondContact O-N 3.05Å; V230-F234 VanDerWaalsContact O-CB 3.32Å; V230-F234 WeakPolarHBondContact O-CB 3.39Å; V230-F234 PolarHBondContact O-N 2.94Å; V230-V388 HydrophobicContact CB-CG1 4.39Å; V230-V388 HydrophobicContact CG1-CG1 4.37Å; V230-V388 HydrophobicContact CG2-CG1 4.02Å; V230-L389 HydrophobicContact CG1-CD2 3.95Å; V230-L389 HydrophobicContact CG2-CD2 4.16Å; V230-V392 HydrophobicContact CG2-CB 4.39Å; V230-V392 HydrophobicContact CG2-CG1 4.25Å
231N95Very high89Confident1 Ų125.1 Ų25.11%0.00515%0.147CC..Hα-helixtrans-60.8-41.3175.2-73.3-7.1000111.3F185 Y188 S210 V227 F234 D235 M275F185-N231 VanDerWaalsContact CD2-OD1 3.26Å; F185-N231 WeakPolarHBondContact CD2-OD1 3.48Å; Y188-N231 HydrophobicContact CD1-CB 3.87Å; Y188-N231 HydrophobicContact CD2-CB 4.49Å; Y188-N231 HydrophobicContact CE1-CB 3.93Å; Y188-N231 HydrophobicContact CG-CB 4.17Å; S210-N231 PolarHBondContact OG-ND2 3.43Å; V227-N231 WeakPolarHBondContact O-CB 3.31Å; V227-N231 VanDerWaalsContact O-CG 3.26Å; V227-N231 PolarHBondContact O-N 3.25Å; N231-F234 WeakPolarHBondContact O-CB 3.44Å; N231-F234 PolarHBondContact O-N 3.45Å; N231-D235 WeakPolarHBondContact O-CB 3.4Å; N231-D235 PolarHBondContact O-N 3.43Å; N231-M275 HydrophobicContact CB-CE 3.38Å; N231-M275 HydrophobicContact CB-SD 4.27Å
232A92.6Very high87.8Confident25 Ų2525.7 Ų25.721%0.20715%0.151CC..Hα-helixtrans-66.5-43.517800000111.7L228 G229 V230 F234 D235 V236 L272 M275L228-A232 VanDerWaalsContact O-CB 3.26Å; L228-A232 WeakPolarHBondContact O-CB 3.31Å; L228-A232 PolarHBondContact O-N 3.3Å; G229-A232 PolarHBondContact O-N 3.33Å; V230-A232 VanDerWaalsContact C-N 3.33Å; V230-A232 PolarHBondContact O-N 3.49Å; A232-F234 VanDerWaalsContact C-N 3.31Å; A232-F234 PolarHBondContact O-N 3.29Å; A232-D235 PolarHBondContact O-N 3.22Å; A232-V236 WeakPolarHBondContact O-CG2 3.21Å; A232-V236 PolarHBondContact O-N 3.27Å; A232-L272 HydrophobicContact CB-CD2 3.73Å; A232-M275 HydrophobicContact CB-CE 4.22Å
233A90.2Very high86.7Confident21 Ų2124.5 Ų24.517%0.17415%0.147CC..Hα-helixtrans-62.1-41.2173.500000111.4G229 V230 L237 V388G229-A233 WeakPolarHBondContact O-CB 3.26Å; G229-A233 PolarHBondContact O-N 3.5Å; V230-A233 PolarHBondContact O-N 3.05Å; A233-L237 HydrophobicContact CB-CD1 4.36Å; A233-L237 WeakPolarHBondContact O-CB 3.37Å; A233-L237 WeakPolarHBondContact O-CD1 3.38Å; A233-L237 WeakPolarHBondContact O-CG 3.44Å; A233-L237 PolarHBondContact O-N 3.14Å; A233-V388 HydrophobicContact CB-CG1 3.88Å; A233-V388 HydrophobicContact CB-CG2 3.91Å
234F89.1Confident85.4Confident0 Ų026.5 Ų26.50%016%0.161CC..Hα-helixtrans-60.4-45.4174.6177.5-93.5000112.6I128 L129 L133 F185 Y188 F192 V230 N231 A232 L238 I239 F385I128-F234 HydrophobicContact CG2-CE2 3.7Å; I128-F234 HydrophobicContact CG2-CZ 4.01Å; L129-F234 HydrophobicContact CD2-CD2 4.06Å; L133-F234 HydrophobicContact CD1-CZ 4.17Å; L133-F234 HydrophobicContact CD2-CZ 4.36Å; L133-F234 HydrophobicContact CG-CZ 4.24Å; F185-F234 HydrophobicContact CE2-CB 4.05Å; F185-F234 AromaticContact CE2-CD2 3.85Å; F185-F234 HydrophobicContact CE2-CD2 3.85Å; F185-F234 HydrophobicContact CE2-CE2 4.41Å; F185-F234 AromaticContact CE2-CG 3.91Å; F185-F234 HydrophobicContact CE2-CG 3.91Å; F185-F234 AromaticContact CZ-CD2 3.82Å; F185-F234 HydrophobicContact CZ-CD2 3.82Å; F185-F234 HydrophobicContact CZ-CE2 4.01Å; F185-F234 HydrophobicContact CZ-CG 4.32Å; Y188-F234 HydrophobicContact CD1-CD1 4.25Å; Y188-F234 HydrophobicContact CE1-CD1 4.09Å; F192-F234 HydrophobicContact CE2-CE1 4.42Å; V230-F234 VanDerWaalsContact O-CB 3.32Å; V230-F234 WeakPolarHBondContact O-CB 3.39Å; V230-F234 PolarHBondContact O-N 2.94Å; N231-F234 WeakPolarHBondContact O-CB 3.44Å; N231-F234 PolarHBondContact O-N 3.45Å; A232-F234 VanDerWaalsContact C-N 3.31Å; A232-F234 PolarHBondContact O-N 3.29Å; F234-L238 HydrophobicContact CD2-CB 4.15Å; F234-L238 HydrophobicContact CD2-CD2 4.22Å; F234-L238 HydrophobicContact CE1-CD2 4.19Å; F234-L238 HydrophobicContact CE2-CB 4.11Å; F234-L238 HydrophobicContact CE2-CD2 3.34Å; F234-L238 HydrophobicContact CE2-CG 4.21Å; F234-L238 HydrophobicContact CZ-CB 4.41Å; F234-L238 HydrophobicContact CZ-CD2 3.32Å; F234-L238 HydrophobicContact CZ-CG 4.43Å; F234-L238 WeakPolarHBondContact O-CA 3.22Å; F234-L238 WeakPolarHBondContact O-CB 3.28Å; F234-L238 PolarHBondContact O-N 3.23Å; F234-I239 HydrophobicContact CD1-CG1 4.34Å; F234-I239 HydrophobicContact CE1-CD1 3.97Å; F234-I239 HydrophobicContact CE1-CG1 4.01Å; F234-I239 HydrophobicContact CZ-CD1 4.44Å; F234-I239 PolarHBondContact O-N 2.89Å; F234-F385 HydrophobicContact CB-CE1 4.07Å; F234-F385 HydrophobicContact CB-CZ 4.4Å; F234-F385 HydrophobicContact CD2-CE1 4.27Å; F234-F385 HydrophobicContact CD2-CZ 4.06Å
235D86.9Confident84Confident0 Ų032.3 Ų32.30%018%0.183CC..Iπ-helixtrans-62.7-49.1179.2-161.41.2000111.7Y188 N231 A232 I239 C240 L268 R271Y188-D235 HydrophobicContact CE1-CB 4.44Å; Y188-D235 WeakPolarHBondContact OH-CB 3.32Å; Y188-D235 VanDerWaalsContact OH-CG 3.28Å; Y188-D235 PolarHBondContact OH-OD2 2.96Å; N231-D235 WeakPolarHBondContact O-CB 3.4Å; N231-D235 PolarHBondContact O-N 3.43Å; A232-D235 PolarHBondContact O-N 3.22Å; D235-I239 WeakPolarHBondContact O-CB 3.5Å; D235-I239 PolarHBondContact O-N 3.02Å; D235-C240 PolarHBondContact O-N 2.92Å; D235-L268 HydrophobicContact CB-CD1 4.19Å; D235-L268 WeakPolarHBondContact OD2-CD1 3.47Å; D235-R271 IonicContact OD1-CZ 3.21Å; D235-R271 IonicContact OD1-NE 3.29Å; D235-R271 PolarHBondContact OD1-NE 3.48Å; D235-R271 IonicContact OD1-NH2 2.75Å; D235-R271 PolarHBondContact OD1-NH2 3.26Å; D235-R271 WeakPolarHBondContact OD2-CB 3.38Å; D235-R271 IonicContact OD2-CZ 2.8Å; D235-R271 IonicContact OD2-NE 2.92Å; D235-R271 PolarHBondContact OD2-NE 2.87Å; D235-R271 IonicContact OD2-NH2 3.83Å
236V83.3Confident82.5Confident42 Ų4234.3 Ų34.326%0.25519%0.192SC..Iπ-helixtrans-64.5-47.6180173.20000111.7A232 V242 L268A232-V236 WeakPolarHBondContact O-CG2 3.21Å; A232-V236 PolarHBondContact O-N 3.27Å; V236-V242 HydrophobicContact CG1-CB 4.11Å; V236-V242 HydrophobicContact CG1-CG2 4.4Å; V236-V242 WeakPolarHBondContact O-CB 3.43Å; V236-V242 PolarHBondContact O-N 3.36Å; V236-L268 HydrophobicContact CG2-CD1 4.24Å; V236-L268 HydrophobicContact CG2-CD2 4.35Å
237L78.6Confident81Confident34 Ų3437.1 Ų37.118%0.17821%0.206CC..Iπ-helixtrans-84.5-38.2-170.5-61.4170.3000112.9A233 V244 T384 F385A233-L237 HydrophobicContact CB-CD1 4.36Å; A233-L237 WeakPolarHBondContact O-CB 3.37Å; A233-L237 WeakPolarHBondContact O-CD1 3.38Å; A233-L237 WeakPolarHBondContact O-CG 3.44Å; A233-L237 PolarHBondContact O-N 3.14Å; L237-V244 HydrophobicContact CD2-CG2 3.49Å; L237-V244 VanDerWaalsContact CD2-CG2 3.49Å; L237-T384 HydrophobicContact CD1-CG2 3.39Å; L237-T384 HydrophobicContact CD2-CG2 4.44Å; L237-F385 HydrophobicContact CB-CZ 3.96Å; L237-F385 HydrophobicContact CD1-CE1 4.2Å; L237-F385 HydrophobicContact CD1-CZ 4.31Å
238L78.4Confident79.4Confident33 Ų3338.4 Ų38.417%0.17322%0.22CC..Iπ-helixtrans-95.3-53.3-176.1-16388.6000112.4L133 F234 R381 F385L133-L238 HydrophobicContact CG-CD2 4.33Å; F234-L238 HydrophobicContact CD2-CB 4.15Å; F234-L238 HydrophobicContact CD2-CD2 4.22Å; F234-L238 HydrophobicContact CE1-CD2 4.19Å; F234-L238 HydrophobicContact CE2-CB 4.11Å; F234-L238 HydrophobicContact CE2-CD2 3.34Å; F234-L238 HydrophobicContact CE2-CG 4.21Å; F234-L238 HydrophobicContact CZ-CB 4.41Å; F234-L238 HydrophobicContact CZ-CD2 3.32Å; F234-L238 HydrophobicContact CZ-CG 4.43Å; F234-L238 WeakPolarHBondContact O-CA 3.22Å; F234-L238 WeakPolarHBondContact O-CB 3.28Å; F234-L238 PolarHBondContact O-N 3.23Å; L238-R381 VanDerWaalsContact CD1-NE 3.27Å; L238-F385 HydrophobicContact CB-CZ 4.25Å; L238-F385 HydrophobicContact CD1-CE2 4.35Å
239I77Confident77.8Confident53 Ų5341.9 Ų41.927%0.27224%0.235SC..Iπ-helixtrans-77.1-47.2-170.2-57.2-60000110.5L133 F192 F234 D235 N241L133-I239 HydrophobicContact CD1-CD1 3.88Å; F192-I239 HydrophobicContact CB-CD1 4.28Å; F192-I239 HydrophobicContact CD1-CD1 4.13Å; F192-I239 HydrophobicContact CD1-CG1 4.27Å; F192-I239 HydrophobicContact CD1-CG2 3.99Å; F192-I239 HydrophobicContact CD2-CD1 3.95Å; F192-I239 HydrophobicContact CD2-CG1 4.27Å; F192-I239 HydrophobicContact CE1-CD1 4.44Å; F192-I239 HydrophobicContact CE1-CG1 4.08Å; F192-I239 HydrophobicContact CE1-CG2 3.84Å; F192-I239 HydrophobicContact CE2-CD1 4.29Å; F192-I239 HydrophobicContact CE2-CG1 4.1Å; F192-I239 HydrophobicContact CG-CD1 3.87Å; F192-I239 HydrophobicContact CG-CG1 4.36Å; F192-I239 HydrophobicContact CZ-CG1 3.99Å; F234-I239 HydrophobicContact CD1-CG1 4.34Å; F234-I239 HydrophobicContact CE1-CD1 3.97Å; F234-I239 HydrophobicContact CE1-CG1 4.01Å; F234-I239 HydrophobicContact CZ-CD1 4.44Å; F234-I239 PolarHBondContact O-N 2.89Å; D235-I239 WeakPolarHBondContact O-CB 3.5Å; D235-I239 PolarHBondContact O-N 3.02Å; I239-N241 VanDerWaalsContact C-N 3.28Å
240C74.1Confident76.3Confident22 Ų2244.5 Ų44.515%0.14924%0.235CC..SBendtrans-83.1-6.1176.7-65.90000113.2D235 V242D235-C240 PolarHBondContact O-N 2.92Å; C240-V242 HydrophobicContact CB-CG2 3.69Å; C240-V242 PolarHBondContact O-N 2.97Å; C240-V242 VanDerWaalsContact O-N 3.1Å
241N72.6Confident74.7Confident101 Ų10150.4 Ų50.454%0.5427%0.266SS..  trans48.636.2-179-166.935.8000113.1I239 N243I239-N241 VanDerWaalsContact C-N 3.28Å; N241-N243 PolarHBondContact O-N 2.89Å
242V69.8Low73.2Confident22 Ų2257.2 Ų57.213%0.13330%0.301CS..  trans-75.3117.6-175.5178.50000109.3V236 C240 V244 L247 I263V236-V242 HydrophobicContact CG1-CB 4.11Å; V236-V242 HydrophobicContact CG1-CG2 4.4Å; V236-V242 WeakPolarHBondContact O-CB 3.43Å; V236-V242 PolarHBondContact O-N 3.36Å; C240-V242 HydrophobicContact CB-CG2 3.69Å; C240-V242 PolarHBondContact O-N 2.97Å; C240-V242 VanDerWaalsContact O-N 3.1Å; V242-V244 PolarHBondContact O-N 3.48Å; V242-L247 HydrophobicContact CG1-CB 4.3Å; V242-L247 HydrophobicContact CG1-CD2 3.91Å; V242-I263 HydrophobicContact CG2-CD1 4.2Å; V242-I263 HydrophobicContact CG2-CG1 4.45Å
243N67.4Low72Confident42 Ų4262.8 Ų62.823%0.22532%0.321CS..  trans-78.7104.7171.1-172.7-3000109.9N241 Y245 E246 L247N241-N243 PolarHBondContact O-N 2.89Å; N243-Y245 PolarHBondContact O-N 3.23Å; N243-Y245 PolarHBondContact OD1-N 2.92Å; N243-E246 HydrophobicContact CB-CB 3.92Å; N243-E246 PolarHBondContact O-N 3.45Å; N243-E246 VanDerWaalsContact O-N 3.1Å; N243-L247 PolarHBondContact O-N 3.05Å
244V66Low70.4Confident60 Ų6073 Ų7336%0.36436%0.355SS..Hα-helixtrans-57.4-36.6-176.8-177.20000112.2L237 V242 G248 L372L237-V244 HydrophobicContact CD2-CG2 3.49Å; L237-V244 VanDerWaalsContact CD2-CG2 3.49Å; V242-V244 PolarHBondContact O-N 3.48Å; V244-G248 PolarHBondContact O-N 3.29Å; V244-L372 HydrophobicContact CB-CD2 3.74Å; V244-L372 HydrophobicContact CG1-CD2 3.63Å; V244-L372 HydrophobicContact CG2-CD2 4.41Å
245Y64.6Low68.9Low121 Ų12181 Ų8148%0.47539%0.39SS..Hα-helixtrans-64.5-45.1177.4175.8-97.1000111.6N243 G248 H249 L372 C373N243-Y245 PolarHBondContact O-N 3.23Å; N243-Y245 PolarHBondContact OD1-N 2.92Å; Y245-G248 PolarHBondContact O-N 3.33Å; Y245-H249 VanDerWaalsContact O-CB 3.26Å; Y245-H249 WeakPolarHBondContact O-CB 3.32Å; Y245-H249 PolarHBondContact O-N 3.29Å; Y245-L372 WeakPolarHBondContact CB-O 3.34Å; Y245-C373 HydrophobicContact CD2-CB 4.46Å
246E65.9Low67Low77 Ų7789.2 Ų89.236%0.3643%0.434SS..Hα-helixtrans-69.9-39.2-178.9-168.8155.3-162.200111.8N243 R250N243-E246 HydrophobicContact CB-CB 3.92Å; N243-E246 PolarHBondContact O-N 3.45Å; N243-E246 VanDerWaalsContact O-N 3.1Å; E246-R250 VanDerWaalsContact O-CB 3.31Å; E246-R250 WeakPolarHBondContact O-CB 3.4Å; E246-R250 WeakPolarHBondContact O-CG 3.13Å; E246-R250 PolarHBondContact O-N 3.44Å; E246-R250 IonicContact OE1-CZ 3.39Å; E246-R250 IonicContact OE1-NE 2.75Å; E246-R250 IonicContact OE1-NH2 3.87Å; E246-R250 PolarHBondContact OE1-NH2 3.04Å
247L64.6Low65.6Low69 Ų6990.1 Ų90.136%0.36144%0.442SS..Hα-helixtrans-62.6-48.8172.4-175.867.6000111.5V242 N243 R250 L251V242-L247 HydrophobicContact CG1-CB 4.3Å; V242-L247 HydrophobicContact CG1-CD2 3.91Å; N243-L247 PolarHBondContact O-N 3.05Å; L247-R250 PolarHBondContact O-N 3.47Å; L247-L251 HydrophobicContact CD1-CD1 4.17Å; L247-L251 HydrophobicContact CD1-CG 4.45Å; L247-L251 HydrophobicContact CG-CD1 3.88Å; L247-L251 WeakPolarHBondContact O-CB 3.32Å; L247-L251 VanDerWaalsContact O-CG 3.26Å; L247-L251 WeakPolarHBondContact O-CG 3.37Å; L247-L251 PolarHBondContact O-N 3.15Å
248G62.8Low64.2Low28 Ų2893.7 Ų93.729%0.28947%0.467SS..Hα-helixtrans-63.6-43.918000000112.7V244 Y245 L251 L252V244-G248 PolarHBondContact O-N 3.29Å; Y245-G248 PolarHBondContact O-N 3.33Å; G248-L251 PolarHBondContact O-N 3.13Å; G248-L252 WeakPolarHBondContact O-CB 3.28Å; G248-L252 WeakPolarHBondContact O-CD1 3.45Å; G248-L252 WeakPolarHBondContact O-CG 3.35Å; G248-L252 PolarHBondContact O-N 3.37Å
249H63.5Low63.1Low94 Ų9495.3 Ų95.344%0.43547%0.474SS..Hα-helixtrans-63.2-45.9176.4-165.373.1000111.2Y245 L251 L252 F253Y245-H249 VanDerWaalsContact O-CB 3.26Å; Y245-H249 WeakPolarHBondContact O-CB 3.32Å; Y245-H249 PolarHBondContact O-N 3.29Å; H249-L251 PolarHBondContact O-N 3.13Å; H249-L252 PolarHBondContact O-N 2.87Å; H249-F253 AromaticContact CE1-CD2 3.63Å; H249-F253 AromaticContact CE1-CE2 3.28Å; H249-F253 WeakPolarHBondContact CE1-CE2 3.3Å; H249-F253 AromaticContact ND1-CD2 3.75Å; H249-F253 AromaticContact ND1-CE2 3.5Å; H249-F253 WeakPolarHBondContact ND1-CE2 3.22Å; H249-F253 AromaticContact NE2-CD2 3.85Å; H249-F253 AromaticContact NE2-CE2 3.93Å; H249-F253 WeakPolarHBondContact O-CD2 3.39Å; H249-F253 PolarHBondContact O-N 3.5Å
250R63.8Low62.2Low89 Ų8997.9 Ų97.934%0.33649%0.488SS..Hα-helixtrans-68-33.7179-70.7174.6-175.8-177.60.6113.4E246 L247 F253 R254 K255 E259E246-R250 VanDerWaalsContact O-CB 3.31Å; E246-R250 WeakPolarHBondContact O-CB 3.4Å; E246-R250 WeakPolarHBondContact O-CG 3.13Å; E246-R250 PolarHBondContact O-N 3.44Å; E246-R250 IonicContact OE1-CZ 3.39Å; E246-R250 IonicContact OE1-NE 2.75Å; E246-R250 IonicContact OE1-NH2 3.87Å; E246-R250 PolarHBondContact OE1-NH2 3.04Å; L247-R250 PolarHBondContact O-N 3.47Å; R250-F253 CarbonylContact O-C 3.57Å; R250-R254 PolarHBondContact O-N 2.89Å; R250-K255 PolarHBondContact O-N 2.99Å; R250-E259 IonicContact CZ-OE1 3.94Å; R250-E259 IonicContact CZ-OE2 3.23Å; R250-E259 IonicContact NH1-OE1 2.65Å; R250-E259 PolarHBondContact NH1-OE1 3.11Å; R250-E259 IonicContact NH1-OE2 3.6Å; R250-E259 PolarHBondContact NH1-OE2 3.43Å
251L61.7Low61.3Low124 Ų124100.7 Ų100.765%0.64951%0.508SS*.Hα-helixtrans-68.3-42.7174.4-77.4168.5000112.3L247 G248 H249 F253 R254L247-L251 HydrophobicContact CD1-CD1 4.17Å; L247-L251 HydrophobicContact CD1-CG 4.45Å; L247-L251 HydrophobicContact CG-CD1 3.88Å; L247-L251 WeakPolarHBondContact O-CB 3.32Å; L247-L251 VanDerWaalsContact O-CG 3.26Å; L247-L251 WeakPolarHBondContact O-CG 3.37Å; L247-L251 PolarHBondContact O-N 3.15Å; G248-L251 PolarHBondContact O-N 3.13Å; H249-L251 PolarHBondContact O-N 3.13Å; L251-F253 VanDerWaalsContact C-N 3.31Å; L251-F253 PolarHBondContact O-N 3.47Å; L251-R254 PolarHBondContact O-N 3.26Å
252L64.5Low60.7Low145 Ų145101.7 Ų101.776%0.75951%0.509SS*.Hα-helixtrans-64.7-34.5175.7-78.6160.4000112.2G248 H249G248-L252 WeakPolarHBondContact O-CB 3.28Å; G248-L252 WeakPolarHBondContact O-CD1 3.45Å; G248-L252 WeakPolarHBondContact O-CG 3.35Å; G248-L252 PolarHBondContact O-N 3.37Å; H249-L252 PolarHBondContact O-N 2.87Å
253F67.6Low60.2Low142 Ų142102.3 Ų102.362%0.62351%0.511SS*.THydrogen-bonded Turntrans-100.313.5-179.3-67.8-72.2000114.7H249 R250 L251 K255H249-F253 AromaticContact CE1-CD2 3.63Å; H249-F253 AromaticContact CE1-CE2 3.28Å; H249-F253 WeakPolarHBondContact CE1-CE2 3.3Å; H249-F253 AromaticContact ND1-CD2 3.75Å; H249-F253 AromaticContact ND1-CE2 3.5Å; H249-F253 WeakPolarHBondContact ND1-CE2 3.22Å; H249-F253 AromaticContact NE2-CD2 3.85Å; H249-F253 AromaticContact NE2-CE2 3.93Å; H249-F253 WeakPolarHBondContact O-CD2 3.39Å; H249-F253 PolarHBondContact O-N 3.5Å; R250-F253 CarbonylContact O-C 3.57Å; L251-F253 VanDerWaalsContact C-N 3.31Å; L251-F253 PolarHBondContact O-N 3.47Å; F253-K255 VanDerWaalsContact C-N 3.33Å; F253-K255 PolarHBondContact O-N 2.85Å; F253-K255 VanDerWaalsContact O-N 3.12Å
254R55.8Low59.8Low236 Ų236105 Ų10589%0.89153%0.525SS*.THydrogen-bonded Turntrans4841167.1-117.5-175.5-173.1-177.22.2115.7R250 L251R250-R254 PolarHBondContact O-N 2.89Å; L251-R254 PolarHBondContact O-N 3.26Å
255K58Low59.4Low167 Ų167112.3 Ų112.373%0.72655%0.546SS*.  trans-86.3128.3170.2-84.8-176.4173.8178.50110.7R250 F253R250-K255 PolarHBondContact O-N 2.99Å; F253-K255 VanDerWaalsContact C-N 3.33Å; F253-K255 PolarHBondContact O-N 2.85Å; F253-K255 VanDerWaalsContact O-N 3.12Å
256N48Very low59.4Low172 Ų172108.8 Ų108.892%0.9254%0.538SS*.  trans-60.9132.9172.7-81.2-14.6000110.7
257S52.3Low59.8Low61 Ų61105.7 Ų105.743%0.42753%0.526SS..  trans-119.4130.2-168.858.20000114.3E259S257-E259 VanDerWaalsContact C-N 3.26Å; S257-E259 PolarHBondContact O-N 3.49Å
258P50.7Low60.7Low109 Ų109103 Ų10371%0.70851%0.512SS*.THydrogen-bonded Turntrans-71.2-15.9167.425-29.8000113.8L260 S261P258-L260 PolarHBondContact O-N 3.02Å; P258-S261 PolarHBondContact O-N 2.91Å; P258-S261 PolarHBondContact O-OG 2.98Å
259E54.7Low61.7Low67 Ų67106.8 Ų106.831%0.31353%0.525SS..Hα-helixtrans-65.8-31.5178.8-103.5165.8-166.300114.5R250 S257 S261 E262 I263R250-E259 IonicContact CZ-OE1 3.94Å; R250-E259 IonicContact CZ-OE2 3.23Å; R250-E259 IonicContact NH1-OE1 2.65Å; R250-E259 PolarHBondContact NH1-OE1 3.11Å; R250-E259 IonicContact NH1-OE2 3.6Å; R250-E259 PolarHBondContact NH1-OE2 3.43Å; S257-E259 VanDerWaalsContact C-N 3.26Å; S257-E259 PolarHBondContact O-N 3.49Å; E259-S261 PolarHBondContact O-N 3.29Å; E259-E262 WeakPolarHBondContact O-CB 3.42Å; E259-E262 PolarHBondContact O-N 3.44Å; E259-I263 WeakPolarHBondContact O-CG1 3.38Å; E259-I263 PolarHBondContact O-N 2.84Å
260L56.8Low62.7Low108 Ų108109.9 Ų109.957%0.56554%0.537SS*.Hα-helixtrans-63.5-35.2-179.5-167.672.9000111.1P258 E262 L264P258-L260 PolarHBondContact O-N 3.02Å; L260-E262 VanDerWaalsContact C-N 3.3Å; L260-E262 PolarHBondContact O-N 3.47Å; L260-L264 HydrophobicContact CG-CD1 4.12Å; L260-L264 WeakPolarHBondContact O-CB 3.41Å; L260-L264 VanDerWaalsContact O-CD1 3.27Å; L260-L264 WeakPolarHBondContact O-CD1 3.41Å; L260-L264 PolarHBondContact O-N 3.44Å
261S56.9Low63.9Low81 Ų81105.9 Ų105.957%0.56652%0.522SS*.Hα-helixtrans-65.7-33.7174.480.40000112.2P258 E259 L264 R265P258-S261 PolarHBondContact O-N 2.91Å; P258-S261 PolarHBondContact O-OG 2.98Å; E259-S261 PolarHBondContact O-N 3.29Å; S261-L264 PolarHBondContact O-N 3.04Å; S261-R265 VanDerWaalsContact O-CB 3.27Å; S261-R265 WeakPolarHBondContact O-CB 3.07Å; S261-R265 PolarHBondContact O-N 3.04Å
262E58.5Low65.3Low121 Ų121102.1 Ų102.157%0.56550%0.503SS*.Hα-helixtrans-76.3-38.7179.8-139.2174.8-171.900111.8E259 L260 L264 R265 T266E259-E262 WeakPolarHBondContact O-CB 3.42Å; E259-E262 PolarHBondContact O-N 3.44Å; L260-E262 VanDerWaalsContact C-N 3.3Å; L260-E262 PolarHBondContact O-N 3.47Å; E262-L264 VanDerWaalsContact C-N 3.34Å; E262-R265 PolarHBondContact O-N 2.83Å; E262-T266 WeakPolarHBondContact O-CG2 3.33Å; E262-T266 PolarHBondContact O-N 3.34Å; E262-T266 PolarHBondContact O-OG1 2.71Å
263I60.4Low66.6Low35 Ų3597.1 Ų97.118%0.17949%0.486CS..Hα-helixtrans-64.6-38.9170.9-66.3168.4000110.9V242 E259 T266 L268V242-I263 HydrophobicContact CG2-CD1 4.2Å; V242-I263 HydrophobicContact CG2-CG1 4.45Å; E259-I263 WeakPolarHBondContact O-CG1 3.38Å; E259-I263 PolarHBondContact O-N 2.84Å; I263-T266 PolarHBondContact O-OG1 2.9Å; I263-L268 HydrophobicContact CG2-CB 4.21Å; I263-L268 HydrophobicContact CG2-CD2 3.52Å; I263-L268 HydrophobicContact CG2-CG 4.48Å
264L58.6Low67.8Low100 Ų10092.6 Ų92.652%0.52447%0.468SS..Hα-helixtrans-66.4-38.8171.2-100.1113.9000112.1L260 S261 E262 T266 G267 L269L260-L264 HydrophobicContact CG-CD1 4.12Å; L260-L264 WeakPolarHBondContact O-CB 3.41Å; L260-L264 VanDerWaalsContact O-CD1 3.27Å; L260-L264 WeakPolarHBondContact O-CD1 3.41Å; L260-L264 PolarHBondContact O-N 3.44Å; S261-L264 PolarHBondContact O-N 3.04Å; E262-L264 VanDerWaalsContact C-N 3.34Å; L264-T266 VanDerWaalsContact C-N 3.34Å; L264-T266 PolarHBondContact O-N 3.47Å; L264-G267 PolarHBondContact O-N 2.69Å; L264-L269 HydrophobicContact CD1-CD1 4.13Å; L264-L269 HydrophobicContact CD2-CD1 3.83Å; L264-L269 HydrophobicContact CG-CD1 3.69Å
265R57.3Low69.6Low212 Ų21281.7 Ų81.780%0.843%0.427SS*.Hα-helixtrans-68.2-30.3-179.7-167.9175.7174.8-171.1-2.1112.9S261 E262 G267S261-R265 VanDerWaalsContact O-CB 3.27Å; S261-R265 WeakPolarHBondContact O-CB 3.07Å; S261-R265 PolarHBondContact O-N 3.04Å; E262-R265 PolarHBondContact O-N 2.83Å; R265-G267 PolarHBondContact O-N 2.7Å
266T64.1Low71.3Confident48 Ų4877 Ų7729%0.29442%0.416SS..THydrogen-bonded Turntrans-77.30.8175.448.90000113.9E262 I263 L264 L268 R271E262-T266 WeakPolarHBondContact O-CG2 3.33Å; E262-T266 PolarHBondContact O-N 3.34Å; E262-T266 PolarHBondContact O-OG1 2.71Å; I263-T266 PolarHBondContact O-OG1 2.9Å; L264-T266 VanDerWaalsContact C-N 3.34Å; L264-T266 PolarHBondContact O-N 3.47Å; T266-L268 VanDerWaalsContact C-N 3.33Å; T266-L268 PolarHBondContact O-N 3.15Å; T266-R271 PolarHBondContact O-NH1 3.42Å
267G76.2Confident73.6Confident11 Ų1174.2 Ų74.211%0.11340%0.4CS..THydrogen-bonded Turntrans75.613.9173.800000115.3L264 R265 L269 K270 R271L264-G267 PolarHBondContact O-N 2.69Å; R265-G267 PolarHBondContact O-N 2.7Å; G267-L269 PolarHBondContact O-N 2.73Å; G267-K270 PolarHBondContact O-N 2.99Å; G267-K270 VanDerWaalsContact O-N 3.15Å; G267-R271 PolarHBondContact O-N 3.4Å
268L82.3Confident75.7Confident13 Ų1372 Ų727%0.06839%0.387CS..Hα-helixtrans-55.3-47.6-178.7179.564.5000112.5D235 V236 I263 T266 K270 R271 L272D235-L268 HydrophobicContact CB-CD1 4.19Å; D235-L268 WeakPolarHBondContact OD2-CD1 3.47Å; V236-L268 HydrophobicContact CG2-CD1 4.24Å; V236-L268 HydrophobicContact CG2-CD2 4.35Å; I263-L268 HydrophobicContact CG2-CB 4.21Å; I263-L268 HydrophobicContact CG2-CD2 3.52Å; I263-L268 HydrophobicContact CG2-CG 4.48Å; T266-L268 VanDerWaalsContact C-N 3.33Å; T266-L268 PolarHBondContact O-N 3.15Å; L268-K270 PolarHBondContact O-N 3.4Å; L268-R271 PolarHBondContact O-N 3.32Å; L268-R271 VanDerWaalsContact O-N 3.11Å; L268-L272 HydrophobicContact CD1-CD1 3.84Å; L268-L272 HydrophobicContact CD1-CD2 4.44Å; L268-L272 HydrophobicContact CD1-CG 3.85Å; L268-L272 HydrophobicContact CD2-CD1 4.28Å; L268-L272 HydrophobicContact CG-CD1 3.81Å; L268-L272 HydrophobicContact CG-CG 4.17Å; L268-L272 PolarHBondContact O-N 3.19Å
269L83.3Confident77.8Confident108 Ų10867 Ų6757%0.56536%0.355SS*.Hα-helixtrans-59.9-35.9-179.9-69.2178.3000112.3L264 G267 G273L264-L269 HydrophobicContact CD1-CD1 4.13Å; L264-L269 HydrophobicContact CD2-CD1 3.83Å; L264-L269 HydrophobicContact CG-CD1 3.69Å; G267-L269 PolarHBondContact O-N 2.73Å; L269-G273 WeakPolarHBondContact O-CA 3.49Å; L269-G273 PolarHBondContact O-N 3.18Å
270K86Confident79.8Confident159 Ų15969.4 Ų69.469%0.69137%0.37SS*.Hα-helixtrans-68.1-41.8176.9-67.7-177.9179.4177.50111.1F202 G267 L268 L274F202-K270 HydrophobicContact CE1-CB 4.13Å; F202-K270 HydrophobicContact CZ-CB 4.18Å; G267-K270 PolarHBondContact O-N 2.99Å; G267-K270 VanDerWaalsContact O-N 3.15Å; L268-K270 PolarHBondContact O-N 3.4Å; K270-L274 VanDerWaalsContact O-CB 3.31Å; K270-L274 WeakPolarHBondContact O-CB 3.46Å; K270-L274 PolarHBondContact O-N 3.19Å
271R89.1Confident81.7Confident4 Ų467.3 Ų67.32%0.01536%0.364CS..Hα-helixtrans-67.8-50.4178.3-68.7-168.6-61.2-85.12.1111.9F202 D235 T266 G267 L268 G273 L274 M275F202-R271 HydrophobicContact CD1-CG 3.7Å; F202-R271 HydrophobicContact CD2-CG 3.81Å; F202-R271 HydrophobicContact CE1-CG 3.62Å; F202-R271 HydrophobicContact CE2-CG 3.73Å; F202-R271 HydrophobicContact CG-CG 3.8Å; F202-R271 HydrophobicContact CZ-CG 3.64Å; D235-R271 IonicContact OD1-CZ 3.21Å; D235-R271 IonicContact OD1-NE 3.29Å; D235-R271 PolarHBondContact OD1-NE 3.48Å; D235-R271 IonicContact OD1-NH2 2.75Å; D235-R271 PolarHBondContact OD1-NH2 3.26Å; D235-R271 WeakPolarHBondContact OD2-CB 3.38Å; D235-R271 IonicContact OD2-CZ 2.8Å; D235-R271 IonicContact OD2-NE 2.92Å; D235-R271 PolarHBondContact OD2-NE 2.87Å; D235-R271 IonicContact OD2-NH2 3.83Å; T266-R271 PolarHBondContact O-NH1 3.42Å; G267-R271 PolarHBondContact O-N 3.4Å; L268-R271 PolarHBondContact O-N 3.32Å; L268-R271 VanDerWaalsContact O-N 3.11Å; R271-G273 VanDerWaalsContact C-N 3.3Å; R271-G273 PolarHBondContact O-N 3.24Å; R271-L274 PolarHBondContact O-N 2.96Å; R271-M275 WeakPolarHBondContact O-CB 3.44Å; R271-M275 WeakPolarHBondContact O-CG 3.42Å; R271-M275 PolarHBondContact O-N 3.06Å
272L90.1Very high83.6Confident46 Ų4665.1 Ų65.124%0.24135%0.345CS..Hα-helixtrans-62-39176.1-67.2-178.4000111.5A232 L268 M275 S276A232-L272 HydrophobicContact CB-CD2 3.73Å; L268-L272 HydrophobicContact CD1-CD1 3.84Å; L268-L272 HydrophobicContact CD1-CD2 4.44Å; L268-L272 HydrophobicContact CD1-CG 3.85Å; L268-L272 HydrophobicContact CD2-CD1 4.28Å; L268-L272 HydrophobicContact CG-CD1 3.81Å; L268-L272 HydrophobicContact CG-CG 4.17Å; L268-L272 PolarHBondContact O-N 3.19Å; L272-M275 PolarHBondContact O-N 3.43Å; L272-S276 WeakPolarHBondContact O-CB 3.31Å; L272-S276 PolarHBondContact O-N 3.31Å; L272-S276 PolarHBondContact O-OG 3.11Å
273G91.1Very high85.2Confident39 Ų3963.4 Ų63.440%0.40234%0.339SS..Hα-helixtrans-61.5-47173.600000112.3L269 R271 S276 L277L269-G273 WeakPolarHBondContact O-CA 3.49Å; L269-G273 PolarHBondContact O-N 3.18Å; R271-G273 VanDerWaalsContact C-N 3.3Å; R271-G273 PolarHBondContact O-N 3.24Å; G273-S276 PolarHBondContact O-N 2.96Å; G273-L277 VanDerWaalsContact O-CB 3.31Å; G273-L277 WeakPolarHBondContact O-CB 3.2Å; G273-L277 PolarHBondContact O-N 3.22Å
274L92.9Very high86.8Confident48 Ų4868.2 Ų68.225%0.25136%0.356SS..Hα-helixtrans-62.7-44.5177.3-178.461.2000111.9V204 V207 L211 K270 R271 G278V204-L274 HydrophobicContact CG1-CD2 4.06Å; V207-L274 HydrophobicContact CB-CD2 3.95Å; V207-L274 HydrophobicContact CG1-CD2 3.53Å; V207-L274 HydrophobicContact CG1-CG 4.09Å; L211-L274 HydrophobicContact CD1-CG 4.3Å; K270-L274 VanDerWaalsContact O-CB 3.31Å; K270-L274 WeakPolarHBondContact O-CB 3.46Å; K270-L274 PolarHBondContact O-N 3.19Å; R271-L274 PolarHBondContact O-N 2.96Å; L274-G278 PolarHBondContact O-N 2.87Å
275M94.4Very high88.5Confident7 Ų765.6 Ų65.63%0.03435%0.349CS..Hα-helixtrans-65.8-41.4176.9-71.3172.156.500112.3Y188 V207 L228 N231 A232 R271 L272 G278 G279Y188-M275 HydrophobicContact CD2-SD 4.49Å; Y188-M275 HydrophobicContact CE2-CG 4.45Å; Y188-M275 HydrophobicContact CE2-SD 3.57Å; Y188-M275 VanDerWaalsContact CE2-SD 3.57Å; V207-M275 HydrophobicContact CG1-CG 4.43Å; L228-M275 HydrophobicContact CB-CE 4.22Å; L228-M275 HydrophobicContact CD2-CE 4.33Å; L228-M275 WeakPolarHBondContact O-CE 3.23Å; N231-M275 HydrophobicContact CB-CE 3.38Å; N231-M275 HydrophobicContact CB-SD 4.27Å; A232-M275 HydrophobicContact CB-CE 4.22Å; R271-M275 WeakPolarHBondContact O-CB 3.44Å; R271-M275 WeakPolarHBondContact O-CG 3.42Å; R271-M275 PolarHBondContact O-N 3.06Å; L272-M275 PolarHBondContact O-N 3.43Å; M275-G278 PolarHBondContact O-N 3.48Å; M275-G279 PolarHBondContact O-N 2.84Å
276S94.6Very high90.1Very high69 Ų6957 Ų5748%0.48332%0.317SS..Hα-helixtrans-66.4-44178.3-58.50000111.1L272 G273 G279 L280L272-S276 WeakPolarHBondContact O-CB 3.31Å; L272-S276 PolarHBondContact O-N 3.31Å; L272-S276 PolarHBondContact O-OG 3.11Å; G273-S276 PolarHBondContact O-N 2.96Å; S276-G279 PolarHBondContact O-N 3.46Å; S276-L280 WeakPolarHBondContact O-CB 3.5Å; S276-L280 VanDerWaalsContact O-CG 3.27Å; S276-L280 WeakPolarHBondContact O-CG 3.12Å; S276-L280 PolarHBondContact O-N 3.42Å
277L95.9Very high91.3Very high112 Ų11261.8 Ų61.859%0.58633%0.33SS*.Hα-helixtrans-61.4-45.4175.4-177.366.1000111.2G273 S281G273-L277 VanDerWaalsContact O-CB 3.31Å; G273-L277 WeakPolarHBondContact O-CB 3.2Å; G273-L277 PolarHBondContact O-N 3.22Å; L277-S281 WeakPolarHBondContact O-CB 3.34Å; L277-S281 PolarHBondContact O-N 3.21Å; L277-S281 PolarHBondContact O-OG 3.32Å
278G95.6Very high92Very high15 Ų1570.4 Ų70.416%0.15536%0.358CS..Hα-helixtrans-59.3-49.9174.700000112.5L274 M275 S281 M282L274-G278 PolarHBondContact O-N 2.87Å; M275-G278 PolarHBondContact O-N 3.48Å; G278-S281 WeakPolarHBondContact O-CB 3.46Å; G278-S281 PolarHBondContact O-N 2.8Å; G278-M282 VanDerWaalsContact O-CG 3.26Å; G278-M282 WeakPolarHBondContact O-CG 3.45Å; G278-M282 PolarHBondContact O-N 3.35Å
279G96.1Very high92.3Very high5 Ų573.2 Ų73.25%0.05237%0.373CS..Hα-helixtrans-61-46.3178.100000113.1M275 S276 S281 M282 L283M275-G279 PolarHBondContact O-N 2.84Å; S276-G279 PolarHBondContact O-N 3.46Å; G279-S281 VanDerWaalsContact C-N 3.34Å; G279-S281 PolarHBondContact O-N 2.9Å; G279-M282 PolarHBondContact O-N 3.01Å; G279-L283 WeakPolarHBondContact O-CG 3.38Å; G279-L283 PolarHBondContact O-N 2.97Å
280L96.4Very high92.4Very high117 Ų11770.1 Ų70.161%0.61336%0.356SS*.Hα-helixtrans-61.9-41175.8-73170.4000111.9S276 M282 L283 Y284S276-L280 WeakPolarHBondContact O-CB 3.5Å; S276-L280 VanDerWaalsContact O-CG 3.27Å; S276-L280 WeakPolarHBondContact O-CG 3.12Å; S276-L280 PolarHBondContact O-N 3.42Å; L280-M282 VanDerWaalsContact C-N 3.33Å; L280-M282 PolarHBondContact O-N 2.89Å; L280-L283 PolarHBondContact O-N 2.91Å; L280-Y284 VanDerWaalsContact O-CB 3.3Å; L280-Y284 WeakPolarHBondContact O-CB 3.26Å; L280-Y284 PolarHBondContact O-N 3.48Å
281S96.3Very high92.3Very high64 Ų6464.2 Ų64.245%0.44834%0.341SS..Hα-helixtrans-61.8-41.7176.3-57.10000111.6L277 G278 G279 Y284 A285L277-S281 WeakPolarHBondContact O-CB 3.34Å; L277-S281 PolarHBondContact O-N 3.21Å; L277-S281 PolarHBondContact O-OG 3.32Å; G278-S281 WeakPolarHBondContact O-CB 3.46Å; G278-S281 PolarHBondContact O-N 2.8Å; G279-S281 VanDerWaalsContact C-N 3.34Å; G279-S281 PolarHBondContact O-N 2.9Å; S281-Y284 PolarHBondContact O-N 3.04Å; S281-A285 WeakPolarHBondContact O-CB 3.47Å; S281-A285 PolarHBondContact O-N 3.45Å
282M95.6Very high91.2Very high34 Ų3470 Ų7017%0.16738%0.376CS..Hα-helixtrans-67.4-43.4177.7-69.9166.851.800112.3C214 G215 M218 I225 G278 G279 L280 A285 R286C214-M282 HydrophobicContact CB-CE 4.2Å; C214-M282 VanDerWaalsContact SG-CE 3.55Å; G215-M282 VanDerWaalsContact CA-CE 3.41Å; M218-M282 HydrophobicContact CB-CE 4.28Å; M218-M282 HydrophobicContact CG-CE 4.01Å; M218-M282 HydrophobicContact SD-CB 4.08Å; M218-M282 HydrophobicContact SD-CE 3.37Å; M218-M282 WeakPolarHBondContact SD-CE 3.45Å; I225-M282 HydrophobicContact CD1-CE 4.1Å; G278-M282 VanDerWaalsContact O-CG 3.26Å; G278-M282 WeakPolarHBondContact O-CG 3.45Å; G278-M282 PolarHBondContact O-N 3.35Å; G279-M282 PolarHBondContact O-N 3.01Å; L280-M282 VanDerWaalsContact C-N 3.33Å; L280-M282 PolarHBondContact O-N 2.89Å; M282-A285 PolarHBondContact O-N 3.49Å; M282-R286 WeakPolarHBondContact O-CB 3.42Å; M282-R286 PolarHBondContact O-N 2.75Å
283L93.3Very high89.9Confident85 Ų8569.7 Ų69.745%0.44539%0.385SS..Hα-helixtrans-63.5-42.4175.3-70.7174.4000111.4M218 I225 G279 L280 R286 W287M218-L283 HydrophobicContact CE-CD2 4.42Å; I225-L283 HydrophobicContact CG1-CD2 4.48Å; G279-L283 WeakPolarHBondContact O-CG 3.38Å; G279-L283 PolarHBondContact O-N 2.97Å; L280-L283 PolarHBondContact O-N 2.91Å; L283-R286 PolarHBondContact O-N 2.83Å; L283-W287 WeakPolarHBondContact O-CB 3.27Å; L283-W287 PolarHBondContact O-N 3.34Å
284Y94Very high88.8Confident136 Ų13673 Ų7353%0.53340%0.399SS..Hα-helixtrans-62.4-46.5175.5177-100.2000111.9L280 S281 R286 W287 R288L280-Y284 VanDerWaalsContact O-CB 3.3Å; L280-Y284 WeakPolarHBondContact O-CB 3.26Å; L280-Y284 PolarHBondContact O-N 3.48Å; S281-Y284 PolarHBondContact O-N 3.04Å; Y284-R286 VanDerWaalsContact C-N 3.33Å; Y284-R286 PolarHBondContact O-N 2.98Å; Y284-W287 HydrophobicContact CD2-CE3 4Å; Y284-W287 HydrophobicContact CD2-CZ3 4.29Å; Y284-W287 HydrophobicContact CE2-CE3 4.02Å; Y284-W287 AromaticContact CE2-CZ3 3.9Å; Y284-W287 HydrophobicContact CE2-CZ3 3.9Å; Y284-W287 PolarHBondContact O-N 2.69Å; Y284-R288 WeakPolarHBondContact O-CB 3.33Å; Y284-R288 PolarHBondContact O-N 3.31Å
285A93.1Very high87.6Confident45 Ų4572.9 Ų72.937%0.37240%0.401SS..Hα-helixtrans-59.4-44.9176.400000111.4S281 M282 R288 I289S281-A285 WeakPolarHBondContact O-CB 3.47Å; S281-A285 PolarHBondContact O-N 3.45Å; M282-A285 PolarHBondContact O-N 3.49Å; A285-R288 PolarHBondContact O-N 3.31Å; A285-I289 WeakPolarHBondContact O-CD1 3.47Å; A285-I289 VanDerWaalsContact O-CG1 3.27Å; A285-I289 WeakPolarHBondContact O-CG1 3.31Å; A285-I289 PolarHBondContact O-N 3.02Å; A285-I289 VanDerWaalsContact O-N 3.08Å
286R91.1Very high86.5Confident32 Ų3277.5 Ų77.512%0.12144%0.441CS..Hα-helixtrans-63.8-44.4177.5-174.6171.3-172.4135.13.3112.2Y84 M218 E222 M282 L283 Y284 R288 I289 M290Y84-R286 PolarHBondContact O-NH2 3.41Å; M218-R286 HydrophobicContact CE-CB 4.16Å; M218-R286 VanDerWaalsContact CE-CD 3.42Å; M218-R286 HydrophobicContact CE-CG 4.42Å; M218-R286 PolarHBondContact O-NH1 3.39Å; E222-R286 IonicContact OE2-NH2 3.32Å; E222-R286 PolarHBondContact OE2-NH2 3.45Å; M282-R286 WeakPolarHBondContact O-CB 3.42Å; M282-R286 PolarHBondContact O-N 2.75Å; L283-R286 PolarHBondContact O-N 2.83Å; Y284-R286 VanDerWaalsContact C-N 3.33Å; Y284-R286 PolarHBondContact O-N 2.98Å; R286-R288 VanDerWaalsContact C-N 3.34Å; R286-R288 PolarHBondContact O-N 3.27Å; R286-I289 PolarHBondContact O-N 2.98Å; R286-M290 HydrophobicContact CG-CG 4.36Å; R286-M290 HydrophobicContact CG-SD 3.55Å; R286-M290 VanDerWaalsContact CG-SD 3.55Å; R286-M290 PolarHBondContact NE-SD 3.41Å; R286-M290 WeakPolarHBondContact O-CB 3.5Å; R286-M290 WeakPolarHBondContact O-CG 3.49Å; R286-M290 PolarHBondContact O-N 2.96Å
287W89.2Confident85.8Confident149 Ų14976.7 Ų76.756%0.56443%0.429SS*.Hα-helixtrans-59.7-44.2175.7175.667.1000111.6L283 Y284 I289 M290 G291 T292L283-W287 WeakPolarHBondContact O-CB 3.27Å; L283-W287 PolarHBondContact O-N 3.34Å; Y284-W287 HydrophobicContact CD2-CE3 4Å; Y284-W287 HydrophobicContact CD2-CZ3 4.29Å; Y284-W287 HydrophobicContact CE2-CE3 4.02Å; Y284-W287 AromaticContact CE2-CZ3 3.9Å; Y284-W287 HydrophobicContact CE2-CZ3 3.9Å; Y284-W287 PolarHBondContact O-N 2.69Å; W287-I289 VanDerWaalsContact C-N 3.31Å; W287-I289 PolarHBondContact O-N 3.26Å; W287-M290 PolarHBondContact O-N 3.44Å; W287-G291 PolarHBondContact O-N 3.13Å; W287-T292 HydrophobicContact CZ2-CG2 4.24Å
288R91.1Very high85.3Confident191 Ų19174.8 Ų74.872%0.72142%0.422SS*.Hα-helixtrans-60.7-38.2176.7-169.8-172.5-176.3179.64.3112.8Y284 A285 R286Y284-R288 WeakPolarHBondContact O-CB 3.33Å; Y284-R288 PolarHBondContact O-N 3.31Å; A285-R288 PolarHBondContact O-N 3.31Å; R286-R288 VanDerWaalsContact C-N 3.34Å; R286-R288 PolarHBondContact O-N 3.27Å
289I90.3Very high84.8Confident73 Ų7380 Ų8037%0.37444%0.442SS..Hα-helixtrans-75.3-46.5-179-66.9163.2000111.4L75 Y84 A285 R286 W287 G291L75-I289 HydrophobicContact CD1-CG2 3.83Å; Y84-I289 HydrophobicContact CD1-CG2 4.38Å; Y84-I289 HydrophobicContact CD2-CG2 4.24Å; Y84-I289 HydrophobicContact CE1-CD1 3.98Å; Y84-I289 HydrophobicContact CE1-CG2 4.02Å; Y84-I289 HydrophobicContact CE2-CG2 3.86Å; Y84-I289 HydrophobicContact CG-CG2 4.46Å; A285-I289 WeakPolarHBondContact O-CD1 3.47Å; A285-I289 VanDerWaalsContact O-CG1 3.27Å; A285-I289 WeakPolarHBondContact O-CG1 3.31Å; A285-I289 PolarHBondContact O-N 3.02Å; A285-I289 VanDerWaalsContact O-N 3.08Å; R286-I289 PolarHBondContact O-N 2.98Å; W287-I289 VanDerWaalsContact C-N 3.31Å; W287-I289 PolarHBondContact O-N 3.26Å; I289-G291 VanDerWaalsContact C-N 3.32Å
290M85.4Confident84.3Confident42 Ų4281.7 Ų81.721%0.20745%0.451CS..Hα-helixtrans-75.3-23-176.4-70.1175.549.800112.9K82 Y84 R286 W287K82-M290 HydrophobicContact CB-CE 4.11Å; K82-M290 WeakPolarHBondContact O-CE 3.44Å; Y84-M290 HydrophobicContact CG-CG 4.46Å; R286-M290 HydrophobicContact CG-CG 4.36Å; R286-M290 HydrophobicContact CG-SD 3.55Å; R286-M290 VanDerWaalsContact CG-SD 3.55Å; R286-M290 PolarHBondContact NE-SD 3.41Å; R286-M290 WeakPolarHBondContact O-CB 3.5Å; R286-M290 WeakPolarHBondContact O-CG 3.49Å; R286-M290 PolarHBondContact O-N 2.96Å; W287-M290 PolarHBondContact O-N 3.44Å
291G82.6Confident83.8Confident36 Ų3678.6 Ų78.637%0.37144%0.435SS..  trans77.8-169.1-17600000113.1W287 I289W287-G291 PolarHBondContact O-N 3.13Å; I289-G291 VanDerWaalsContact C-N 3.32Å
292T65.9Low83.5Confident124 Ų12475.6 Ų75.676%0.76141%0.414SS*.SBendtrans-91.1113.5-177.552.70000111W287W287-T292 HydrophobicContact CZ2-CG2 4.24Å
293G64.1Low83.2Confident41 Ų4175.2 Ų75.242%0.42341%0.414SS..  trans143.3117.3171.100000111.9
294P66.3Low83Confident109 Ų10971.1 Ų71.171%0.70839%0.393SS*.  trans-64.4161.8168.530-33.9000110.2A296P294-A296 PolarHBondContact O-N 2.8Å
295P68.8Low82.9Confident45 Ų4564.7 Ų64.729%0.29237%0.368SS..  trans-54.3136.2170.4-17.828.7000110.2F297P295-F297 HydrophobicContact CB-CE1 4.3Å; P295-F297 HydrophobicContact CB-CE2 4.03Å; P295-F297 HydrophobicContact CB-CZ 3.85Å; P295-F297 HydrophobicContact CG-CE2 4.33Å; P295-F297 HydrophobicContact CG-CZ 4.13Å; P295-F297 PolarHBondContact O-N 3.32Å
296A70.9Confident82.8Confident104 Ų10466.1 Ų66.186%0.8637%0.365SS*.  trans-76.7104.9172.600000108.6P294P294-A296 PolarHBondContact O-N 2.8Å
297F80.9Confident82.8Confident52 Ų5266.3 Ų66.323%0.22837%0.368CS..  trans-86.6160169.6-62-66.3000110.2P295 F306 R403P295-F297 HydrophobicContact CB-CE1 4.3Å; P295-F297 HydrophobicContact CB-CE2 4.03Å; P295-F297 HydrophobicContact CB-CZ 3.85Å; P295-F297 HydrophobicContact CG-CE2 4.33Å; P295-F297 HydrophobicContact CG-CZ 4.13Å; P295-F297 PolarHBondContact O-N 3.32Å; F297-F306 HydrophobicContact CB-CE2 4.49Å; F297-F306 WeakPolarHBondContact O-CZ 3.48Å; F297-R403 WeakPolarHBondContact CE2-O 3.33Å
298T83.9Confident82.9Confident72 Ų7267.9 Ų67.944%0.44238%0.381SS..  trans-112.4164175.966.80000111V300 D301 N302 F306T298-V300 PolarHBondContact O-N 2.98Å; T298-D301 PolarHBondContact N-OD2 3.49Å; T298-D301 WeakPolarHBondContact O-CB 3.37Å; T298-D301 PolarHBondContact O-N 3.32Å; T298-D301 PolarHBondContact OG1-OD2 3.09Å; T298-N302 PolarHBondContact O-N 2.94Å; T298-F306 VanDerWaalsContact O-CE2 3.28Å; T298-F306 WeakPolarHBondContact O-CE2 3.43Å
299E85.5Confident83Confident125 Ų12562.7 Ų62.758%0.58437%0.368SS*.THydrogen-bonded Turntrans-56.6-29.5173.8-173.8-176.7172.100112.2D301 N302 P303 F306E299-D301 VanDerWaalsContact C-N 3.31Å; E299-D301 PolarHBondContact O-N 3.45Å; E299-N302 CarbonylContact O-C 3.46Å; E299-P303 HydrophobicContact CG-CB 4.3Å; E299-P303 WeakPolarHBondContact O-CA 3.29Å; E299-P303 WeakPolarHBondContact O-CD 3.42Å; E299-F306 HydrophobicContact CB-CB 4.21Å; E299-F306 HydrophobicContact CB-CD2 4.2Å; E299-F306 HydrophobicContact CB-CG 4.12Å; E299-F306 HydrophobicContact CG-CB 4.15Å
300V85.4Confident83.1Confident39 Ų3964.6 Ų64.624%0.23638%0.378CS..THydrogen-bonded Turntrans-69.1-30.8179.6-178.40000112.1T298 M340T298-V300 PolarHBondContact O-N 2.98Å; V300-M340 HydrophobicContact CG1-CB 4.25Å; V300-M340 HydrophobicContact CG1-CE 3.56Å; V300-M340 HydrophobicContact CG1-CG 3.45Å; V300-M340 VanDerWaalsContact CG1-CG 3.45Å; V300-M340 HydrophobicContact CG1-SD 3.24Å; V300-M340 WeakPolarHBondContact CG1-SD 3.48Å; V300-M340 PolarHBondContact O-N 3.13Å
301D85.9Confident83.5Confident52 Ų5269.5 Ų69.528%0.27840%0.398SS..THydrogen-bonded Turntrans-75.3-50.8176.9-56.5-57.3000110.6T298 E299 G405 V407T298-D301 PolarHBondContact N-OD2 3.49Å; T298-D301 WeakPolarHBondContact O-CB 3.37Å; T298-D301 PolarHBondContact O-N 3.32Å; T298-D301 PolarHBondContact OG1-OD2 3.09Å; E299-D301 VanDerWaalsContact C-N 3.31Å; E299-D301 PolarHBondContact O-N 3.45Å; D301-G405 CarbonylContact C-O 3.55Å; D301-G405 VanDerWaalsContact C-O 3.31Å; D301-V407 WeakPolarHBondContact O-CG2 3.34Å
302N89.7Confident84Confident1 Ų169.2 Ų69.21%0.00539%0.388CS..  trans-142.590.3-178.4-177.9-13.8000111.2T298 E299 A304 S305 F306 N399 V404 V407T298-N302 PolarHBondContact O-N 2.94Å; E299-N302 CarbonylContact O-C 3.46Å; N302-A304 VanDerWaalsContact C-N 3.27Å; N302-A304 PolarHBondContact O-N 3Å; N302-A304 PolarHBondContact OD1-N 3.47Å; N302-S305 PolarHBondContact ND2-OG 3.47Å; N302-S305 PolarHBondContact O-N 3.4Å; N302-S305 PolarHBondContact OD1-N 2.72Å; N302-F306 VanDerWaalsContact O-CD2 3.32Å; N302-F306 WeakPolarHBondContact O-CD2 3.38Å; N302-N399 PolarHBondContact ND2-OD1 3.02Å; N302-V404 PolarHBondContact ND2-O 3.18Å; N302-V407 HydrophobicContact CB-CG2 3.57Å; N302-V407 VanDerWaalsContact CG-CG2 3.49Å
303P89.4Confident85.3Confident26 Ų2665.9 Ų65.917%0.16936%0.361CS..Hα-helixtrans-64-32.2-174.823.6-33.3000112.4E299 S305 F306 E307 L345E299-P303 HydrophobicContact CG-CB 4.3Å; E299-P303 WeakPolarHBondContact O-CA 3.29Å; E299-P303 WeakPolarHBondContact O-CD 3.42Å; P303-S305 VanDerWaalsContact C-N 3.29Å; P303-S305 PolarHBondContact O-N 3.33Å; P303-F306 PolarHBondContact O-N 3.49Å; P303-F306 VanDerWaalsContact O-N 3.14Å; P303-E307 PolarHBondContact O-N 3.42Å; P303-L345 HydrophobicContact CB-CD1 4.12Å; P303-L345 HydrophobicContact CB-CD2 4.22Å; P303-L345 HydrophobicContact CB-CG 4.23Å; P303-L345 HydrophobicContact CG-CD2 4.19Å; P303-L345 HydrophobicContact CG-CG 4.42Å
304A90.6Very high86.7Confident0 Ų068.2 Ų68.20%036%0.363CS..Hα-helixtrans-65.1-34.1-17900000112.3N302 F306 E307 R313 N316 Y317 Y320 L345N302-A304 VanDerWaalsContact C-N 3.27Å; N302-A304 PolarHBondContact O-N 3Å; N302-A304 PolarHBondContact OD1-N 3.47Å; A304-F306 PolarHBondContact O-N 3.34Å; A304-E307 PolarHBondContact O-N 2.78Å; A304-R313 WeakPolarHBondContact O-CG 3.26Å; A304-N316 HydrophobicContact CB-CB 3.56Å; A304-Y317 HydrophobicContact CB-CD1 4.01Å; A304-Y317 HydrophobicContact CB-CE1 3.9Å; A304-Y320 HydrophobicContact CB-CE2 3.55Å; A304-Y320 VanDerWaalsContact CB-OH 3.3Å; A304-Y320 WeakPolarHBondContact CB-OH 3.5Å; A304-L345 HydrophobicContact CB-CD2 3.73Å
305S90.6Very high88.1Confident1 Ų164.2 Ų64.21%0.00734%0.337CS..Hα-helixtrans-67.2-20178-73.20000114.1N302 P303 Y317 R403N302-S305 PolarHBondContact ND2-OG 3.47Å; N302-S305 PolarHBondContact O-N 3.4Å; N302-S305 PolarHBondContact OD1-N 2.72Å; P303-S305 VanDerWaalsContact C-N 3.29Å; P303-S305 PolarHBondContact O-N 3.33Å; S305-Y317 WeakPolarHBondContact CA-OH 3.24Å; S305-Y317 PolarHBondContact OG-OH 3.44Å; S305-R403 PolarHBondContact O-NE 3.48Å
306F90.5Very high89.3Confident74 Ų7462.1 Ų62.133%0.32532%0.323SS..Hα-helixtrans-100.3-10.1179.6-69.5-91.4000113.5F297 T298 E299 N302 P303 A304 E308F297-F306 HydrophobicContact CB-CE2 4.49Å; F297-F306 WeakPolarHBondContact O-CZ 3.48Å; T298-F306 VanDerWaalsContact O-CE2 3.28Å; T298-F306 WeakPolarHBondContact O-CE2 3.43Å; E299-F306 HydrophobicContact CB-CB 4.21Å; E299-F306 HydrophobicContact CB-CD2 4.2Å; E299-F306 HydrophobicContact CB-CG 4.12Å; E299-F306 HydrophobicContact CG-CB 4.15Å; N302-F306 VanDerWaalsContact O-CD2 3.32Å; N302-F306 WeakPolarHBondContact O-CD2 3.38Å; P303-F306 PolarHBondContact O-N 3.49Å; P303-F306 VanDerWaalsContact O-N 3.14Å; A304-F306 PolarHBondContact O-N 3.34Å; F306-E308 PolarHBondContact O-N 3.42Å
307E91.1Very high90.4Very high37 Ų3758.2 Ų58.217%0.17329%0.286CS..  trans-60.7129.5173.3-84.5-68.7177.500112P303 A304 N309 I312 R313 L345 K347P303-E307 PolarHBondContact O-N 3.42Å; A304-E307 PolarHBondContact O-N 2.78Å; E307-N309 PolarHBondContact O-N 2.96Å; E307-I312 HydrophobicContact CB-CG2 4.48Å; E307-I312 HydrophobicContact CG-CG2 4.19Å; E307-R313 PolarHBondContact O-NE 3.35Å; E307-R313 PolarHBondContact O-NH2 3.23Å; E307-L345 HydrophobicContact CG-CD1 3.42Å; E307-L345 VanDerWaalsContact CG-CD1 3.42Å; E307-L345 WeakPolarHBondContact OE1-CD1 3.34Å; E307-K347 WeakPolarHBondContact OE1-CE 3.5Å; E307-K347 IonicContact OE1-NZ 2.75Å
308E91.9Very high91.1Very high181 Ų18156.8 Ų56.885%0.84628%0.281SS*.SBendtrans-68.1-36.6-176.1-63.6-174.9169.600112.1F306 I310F306-E308 PolarHBondContact O-N 3.42Å; E308-I310 PolarHBondContact O-N 3.32Å
309N94.1Very high91.6Very high82 Ų8254.3 Ų54.344%0.43926%0.264SS..  trans-77.1115.4-178.6-172.8-33.5000111.3E307 F311 I312 R313E307-N309 PolarHBondContact O-N 2.96Å; N309-F311 VanDerWaalsContact C-N 3.28Å; N309-F311 PolarHBondContact O-N 2.94Å; N309-F311 WeakPolarHBondContact OD1-CB 3.38Å; N309-F311 PolarHBondContact OD1-N 3.15Å; N309-I312 HydrophobicContact CB-CB 4.13Å; N309-I312 HydrophobicContact CB-CD1 4.03Å; N309-I312 HydrophobicContact CB-CG1 4.1Å; N309-I312 PolarHBondContact O-N 2.86Å; N309-I312 PolarHBondContact OD1-N 3.24Å; N309-R313 WeakPolarHBondContact O-CB 3.27Å; N309-R313 PolarHBondContact O-N 2.79Å
310I92.2Very high92Very high113 Ų11348.5 Ų48.558%0.57924%0.236SC*.Hα-helixtrans-59.1-37.8-179.3-61.4170.3000111.9E308 R313 I314E308-I310 PolarHBondContact O-N 3.32Å; I310-R313 WeakPolarHBondContact O-CB 3.36Å; I310-R313 PolarHBondContact O-N 3.18Å; I310-I314 HydrophobicContact CG2-CD1 3.84Å; I310-I314 HydrophobicContact CG2-CG1 4.4Å; I310-I314 VanDerWaalsContact O-CG1 3.3Å; I310-I314 WeakPolarHBondContact O-CG1 3.27Å; I310-I314 PolarHBondContact O-N 3.25Å
311F93Very high92.4Very high146 Ų14648.4 Ų48.464%0.6423%0.232SC*.Hα-helixtrans-66.1-47.4179.5-178.4-94.7000111.2N309 R313 I314 V315N309-F311 VanDerWaalsContact C-N 3.28Å; N309-F311 PolarHBondContact O-N 2.94Å; N309-F311 WeakPolarHBondContact OD1-CB 3.38Å; N309-F311 PolarHBondContact OD1-N 3.15Å; F311-R313 VanDerWaalsContact C-N 3.28Å; F311-R313 PolarHBondContact O-N 2.96Å; F311-I314 PolarHBondContact O-N 3.27Å; F311-V315 HydrophobicContact CD1-CG2 4.09Å; F311-V315 HydrophobicContact CE1-CG2 3.7Å; F311-V315 HydrophobicContact CE2-CG2 4.49Å; F311-V315 HydrophobicContact CZ-CG2 3.93Å; F311-V315 WeakPolarHBondContact O-CG2 3.42Å; F311-V315 PolarHBondContact O-N 3.42Å
312I93.7Very high92.9Very high30 Ų3046.6 Ų46.615%0.15422%0.223CC..Hα-helixtrans-60-42.2175.8-67.2-179.6000110.1E307 N309 V315 N316E307-I312 HydrophobicContact CB-CG2 4.48Å; E307-I312 HydrophobicContact CG-CG2 4.19Å; N309-I312 HydrophobicContact CB-CB 4.13Å; N309-I312 HydrophobicContact CB-CD1 4.03Å; N309-I312 HydrophobicContact CB-CG1 4.1Å; N309-I312 PolarHBondContact O-N 2.86Å; N309-I312 PolarHBondContact OD1-N 3.24Å; I312-V315 PolarHBondContact O-N 3.31Å; I312-N316 WeakPolarHBondContact CG2-ND2 3.32Å; I312-N316 WeakPolarHBondContact O-CB 3.24Å; I312-N316 PolarHBondContact O-N 2.87Å; I312-N316 PolarHBondContact O-ND2 2.93Å
313R93.5Very high93.1Very high54 Ų5447.2 Ų47.220%0.20423%0.227CC..Hα-helixtrans-58.1-49.6175.4-176.7-179.4-53.8164.93.9112A304 E307 N309 I310 F311 N316 Y317A304-R313 WeakPolarHBondContact O-CG 3.26Å; E307-R313 PolarHBondContact O-NE 3.35Å; E307-R313 PolarHBondContact O-NH2 3.23Å; N309-R313 WeakPolarHBondContact O-CB 3.27Å; N309-R313 PolarHBondContact O-N 2.79Å; I310-R313 WeakPolarHBondContact O-CB 3.36Å; I310-R313 PolarHBondContact O-N 3.18Å; F311-R313 VanDerWaalsContact C-N 3.28Å; F311-R313 PolarHBondContact O-N 2.96Å; R313-N316 PolarHBondContact O-N 3.46Å; R313-Y317 HydrophobicContact CG-CD1 4.47Å; R313-Y317 HydrophobicContact CG-CD2 4.35Å; R313-Y317 HydrophobicContact CG-CE1 3.92Å; R313-Y317 HydrophobicContact CG-CE2 3.81Å; R313-Y317 WeakPolarHBondContact O-CD1 3.37Å; R313-Y317 PolarHBondContact O-N 3.46Å
314I93.2Very high93.3Very high89 Ų8946.4 Ų46.446%0.45622%0.221SC..Hα-helixtrans-62.1-45.2178.8-69.4167.5000111.2I310 F311 N316 Y317 N318I310-I314 HydrophobicContact CG2-CD1 3.84Å; I310-I314 HydrophobicContact CG2-CG1 4.4Å; I310-I314 VanDerWaalsContact O-CG1 3.3Å; I310-I314 WeakPolarHBondContact O-CG1 3.27Å; I310-I314 PolarHBondContact O-N 3.25Å; F311-I314 PolarHBondContact O-N 3.27Å; I314-N316 VanDerWaalsContact C-N 3.33Å; I314-N316 PolarHBondContact O-N 2.94Å; I314-Y317 PolarHBondContact O-N 3.03Å; I314-N318 PolarHBondContact O-N 3.12Å; I314-N318 PolarHBondContact O-ND2 3.42Å
315V95Very high93.5Very high26 Ų2647.7 Ų47.716%0.15823%0.231CC..Hα-helixtrans-57.9-47.5177.41690000110.3F311 I312 N318 Y319 I346 L357F311-V315 HydrophobicContact CD1-CG2 4.09Å; F311-V315 HydrophobicContact CE1-CG2 3.7Å; F311-V315 HydrophobicContact CE2-CG2 4.49Å; F311-V315 HydrophobicContact CZ-CG2 3.93Å; F311-V315 WeakPolarHBondContact O-CG2 3.42Å; F311-V315 PolarHBondContact O-N 3.42Å; I312-V315 PolarHBondContact O-N 3.31Å; V315-N318 PolarHBondContact O-N 2.72Å; V315-Y319 PolarHBondContact O-N 3.03Å; V315-I346 HydrophobicContact CG1-CB 4.2Å; V315-I346 HydrophobicContact CG1-CD1 4.48Å; V315-I346 HydrophobicContact CG1-CG2 3.95Å; V315-L357 HydrophobicContact CG1-CD2 3.81Å; V315-L357 WeakPolarHBondContact O-CD2 3.48Å
316N94.4Very high93.7Very high0 Ų052.6 Ų52.60%025%0.25CS..Hα-helixtrans-68.9-35.8-179.1-77.3-80.4000113.1A304 I312 R313 I314 N318 Y319 Y320 L345 I346A304-N316 HydrophobicContact CB-CB 3.56Å; I312-N316 WeakPolarHBondContact CG2-ND2 3.32Å; I312-N316 WeakPolarHBondContact O-CB 3.24Å; I312-N316 PolarHBondContact O-N 2.87Å; I312-N316 PolarHBondContact O-ND2 2.93Å; R313-N316 PolarHBondContact O-N 3.46Å; I314-N316 VanDerWaalsContact C-N 3.33Å; I314-N316 PolarHBondContact O-N 2.94Å; N316-N318 VanDerWaalsContact C-N 3.33Å; N316-N318 PolarHBondContact O-N 3.3Å; N316-Y319 WeakPolarHBondContact O-CB 3.44Å; N316-Y319 PolarHBondContact O-N 3.34Å; N316-Y320 WeakPolarHBondContact O-CD1 3.41Å; N316-Y320 WeakPolarHBondContact O-CD2 3.39Å; N316-Y320 PolarHBondContact O-N 3Å; N316-L345 HydrophobicContact CB-CD2 4.14Å; N316-L345 WeakPolarHBondContact OD1-CA 3.42Å; N316-I346 PolarHBondContact ND2-O 3.41Å; N316-I346 PolarHBondContact OD1-N 3.47Å
317Y93.9Very high93.9Very high22 Ų2249.2 Ų49.29%0.08624%0.235CC..Hα-helixtrans-60.6-42.7171.4-69.6-5.5000111.9A304 S305 R313 I314 Y319 Y320 Y321 N399A304-Y317 HydrophobicContact CB-CD1 4.01Å; A304-Y317 HydrophobicContact CB-CE1 3.9Å; S305-Y317 WeakPolarHBondContact CA-OH 3.24Å; S305-Y317 PolarHBondContact OG-OH 3.44Å; R313-Y317 HydrophobicContact CG-CD1 4.47Å; R313-Y317 HydrophobicContact CG-CD2 4.35Å; R313-Y317 HydrophobicContact CG-CE1 3.92Å; R313-Y317 HydrophobicContact CG-CE2 3.81Å; R313-Y317 WeakPolarHBondContact O-CD1 3.37Å; R313-Y317 PolarHBondContact O-N 3.46Å; I314-Y317 PolarHBondContact O-N 3.03Å; Y317-Y319 VanDerWaalsContact C-N 3.3Å; Y317-Y319 PolarHBondContact O-N 3.47Å; Y317-Y320 HydrophobicContact CD1-CD2 4.11Å; Y317-Y320 HydrophobicContact CD1-CE2 4.16Å; Y317-Y320 WeakPolarHBondContact O-CB 3.28Å; Y317-Y320 PolarHBondContact O-N 3.41Å; Y317-Y320 VanDerWaalsContact O-N 3.15Å; Y317-Y321 WeakPolarHBondContact O-CD1 3.48Å; Y317-Y321 WeakPolarHBondContact O-CE1 3.41Å; Y317-Y321 VanDerWaalsContact O-CG 3.29Å; Y317-Y321 PolarHBondContact O-N 3.47Å; Y317-N399 HydrophobicContact CD1-CB 4.27Å; Y317-N399 HydrophobicContact CD2-CB 3.93Å; Y317-N399 HydrophobicContact CE1-CB 3.99Å; Y317-N399 HydrophobicContact CE2-CB 3.62Å; Y317-N399 HydrophobicContact CG-CB 4.24Å
318N94.6Very high94.1Very high23 Ų2347.9 Ų47.912%0.12323%0.229CC..Hα-helixtrans-66.4-33.3175.3-77.7-80.5000112.8I314 V315 N316 Y320 Y321 S322 L357 W361I314-N318 PolarHBondContact O-N 3.12Å; I314-N318 PolarHBondContact O-ND2 3.42Å; V315-N318 PolarHBondContact O-N 2.72Å; N316-N318 VanDerWaalsContact C-N 3.33Å; N316-N318 PolarHBondContact O-N 3.3Å; N318-Y320 VanDerWaalsContact C-N 3.34Å; N318-Y321 HydrophobicContact CB-CD2 4.43Å; N318-Y321 PolarHBondContact O-N 3.06Å; N318-S322 PolarHBondContact O-N 3.42Å; N318-S322 PolarHBondContact O-OG 2.93Å; N318-L357 HydrophobicContact CB-CD2 3.98Å; N318-L357 HydrophobicContact CB-CG 4.06Å; N318-W361 VanDerWaalsContact OD1-CE2 3.3Å; N318-W361 VanDerWaalsContact OD1-CZ2 3.28Å; N318-W361 WeakPolarHBondContact OD1-CZ2 3.25Å; N318-W361 PolarHBondContact OD1-NE1 3.05Å
319Y95.1Very high94.2Very high19 Ų1944.2 Ų44.28%0.07522%0.215CC..Hα-helixtrans-63.9-41.6171.2-174.2-129.1000111.4V315 N316 Y317 Y321 S322 L323 V343 I346 R353 L357V315-Y319 PolarHBondContact O-N 3.03Å; N316-Y319 WeakPolarHBondContact O-CB 3.44Å; N316-Y319 PolarHBondContact O-N 3.34Å; Y317-Y319 VanDerWaalsContact C-N 3.3Å; Y317-Y319 PolarHBondContact O-N 3.47Å; Y319-Y321 VanDerWaalsContact C-N 3.3Å; Y319-Y321 PolarHBondContact O-N 3.47Å; Y319-S322 WeakPolarHBondContact O-CA 3.41Å; Y319-S322 VanDerWaalsContact O-CB 3.31Å; Y319-S322 WeakPolarHBondContact O-CB 3.21Å; Y319-S322 PolarHBondContact O-N 3.06Å; Y319-L323 HydrophobicContact CD1-CD1 4.22Å; Y319-L323 HydrophobicContact CE1-CD1 3.89Å; Y319-L323 HydrophobicContact CE1-CG 4.35Å; Y319-L323 HydrophobicContact CE2-CD2 4.35Å; Y319-L323 HydrophobicContact CE2-CG 4.32Å; Y319-L323 PolarHBondContact O-N 3Å; Y319-V343 HydrophobicContact CD1-CG1 3.97Å; Y319-V343 HydrophobicContact CE1-CG1 3.66Å; Y319-I346 HydrophobicContact CD1-CD1 3.9Å; Y319-I346 HydrophobicContact CD1-CG1 4.38Å; Y319-I346 HydrophobicContact CD2-CD1 3.99Å; Y319-I346 HydrophobicContact CE1-CD1 4.46Å; Y319-I346 HydrophobicContact CG-CD1 3.63Å; Y319-R353 HydrophobicContact CD2-CB 4.42Å; Y319-R353 HydrophobicContact CE2-CB 3.87Å; Y319-R353 HydrophobicContact CE2-CG 4.39Å; Y319-R353 WeakPolarHBondContact OH-CD 3.45Å; Y319-L357 HydrophobicContact CD2-CD1 3.57Å; Y319-L357 HydrophobicContact CG-CD1 4.1Å
320Y93.7Very high94.1Very high3 Ų342.5 Ų42.51%0.01221%0.209CC..Hα-helixtrans-61.1-39174-56.3-25000112A304 N316 Y317 N318 S322 L323 N324 V343 V407A304-Y320 HydrophobicContact CB-CE2 3.55Å; A304-Y320 VanDerWaalsContact CB-OH 3.3Å; A304-Y320 WeakPolarHBondContact CB-OH 3.5Å; N316-Y320 WeakPolarHBondContact O-CD1 3.41Å; N316-Y320 WeakPolarHBondContact O-CD2 3.39Å; N316-Y320 PolarHBondContact O-N 3Å; Y317-Y320 HydrophobicContact CD1-CD2 4.11Å; Y317-Y320 HydrophobicContact CD1-CE2 4.16Å; Y317-Y320 WeakPolarHBondContact O-CB 3.28Å; Y317-Y320 PolarHBondContact O-N 3.41Å; Y317-Y320 VanDerWaalsContact O-N 3.15Å; N318-Y320 VanDerWaalsContact C-N 3.34Å; Y320-S322 VanDerWaalsContact C-N 3.28Å; Y320-S322 PolarHBondContact O-N 3.44Å; Y320-L323 PolarHBondContact O-N 3.02Å; Y320-N324 PolarHBondContact O-N 3.12Å; Y320-N324 PolarHBondContact O-ND2 3.22Å; Y320-V343 HydrophobicContact CD1-CG1 4.12Å; Y320-V343 HydrophobicContact CE1-CB 4.18Å; Y320-V343 HydrophobicContact CE1-CG1 3.68Å; Y320-V407 HydrophobicContact CD1-CG1 3.32Å; Y320-V407 HydrophobicContact CD2-CG1 3.48Å; Y320-V407 VanDerWaalsContact CD2-CG1 3.48Å; Y320-V407 HydrophobicContact CE1-CG1 3.26Å; Y320-V407 HydrophobicContact CE2-CB 4.31Å; Y320-V407 HydrophobicContact CE2-CG1 3.39Å; Y320-V407 HydrophobicContact CE2-CG2 4.05Å; Y320-V407 HydrophobicContact CG-CG1 3.42Å; Y320-V407 VanDerWaalsContact CG-CG1 3.42Å
321Y94.5Very high94.1Very high38 Ų3837.5 Ų37.515%0.14918%0.183CC..Hα-helixtrans-62.3-39173.3-51.4-20.8000111.6Y317 N318 Y319 N324 A325 F394 C398Y317-Y321 WeakPolarHBondContact O-CD1 3.48Å; Y317-Y321 WeakPolarHBondContact O-CE1 3.41Å; Y317-Y321 VanDerWaalsContact O-CG 3.29Å; Y317-Y321 PolarHBondContact O-N 3.47Å; N318-Y321 HydrophobicContact CB-CD2 4.43Å; N318-Y321 PolarHBondContact O-N 3.06Å; Y319-Y321 VanDerWaalsContact C-N 3.3Å; Y319-Y321 PolarHBondContact O-N 3.47Å; Y321-N324 PolarHBondContact O-N 3.21Å; Y321-A325 WeakPolarHBondContact O-CB 3.25Å; Y321-A325 PolarHBondContact O-N 3.12Å; Y321-F394 AromaticContact CD1-CE1 3.76Å; Y321-F394 HydrophobicContact CD1-CE1 3.76Å; Y321-F394 HydrophobicContact CD1-CZ 4.18Å; Y321-F394 HydrophobicContact CE1-CE1 4.25Å; Y321-F394 HydrophobicContact CG-CE1 4.42Å; Y321-C398 HydrophobicContact CE1-CB 3.69Å; Y321-C398 WeakPolarHBondContact CE1-O 3.26Å; Y321-C398 PolarHBondContact OH-O 2.97Å
322S95.1Very high93.9Very high13 Ų1338 Ų389%0.09118%0.181CC..Hα-helixtrans-65-40.2178.1-52.10000111.3N318 Y319 Y320 A325 W326 W356 L360N318-S322 PolarHBondContact O-N 3.42Å; N318-S322 PolarHBondContact O-OG 2.93Å; Y319-S322 WeakPolarHBondContact O-CA 3.41Å; Y319-S322 VanDerWaalsContact O-CB 3.31Å; Y319-S322 WeakPolarHBondContact O-CB 3.21Å; Y319-S322 PolarHBondContact O-N 3.06Å; Y320-S322 VanDerWaalsContact C-N 3.28Å; Y320-S322 PolarHBondContact O-N 3.44Å; S322-A325 PolarHBondContact O-N 3.2Å; S322-W326 WeakPolarHBondContact O-CB 3.26Å; S322-W326 PolarHBondContact O-N 3.25Å; S322-W356 PolarHBondContact OG-O 3.02Å; S322-L360 WeakPolarHBondContact OG-CD2 3.41Å
323L94Very high93.7Very high15 Ų1540.6 Ų40.68%0.07919%0.189CC..Hα-helixtrans-65.2-44.4174-69175000112Y319 Y320 A325 W326 L327 W333 V343 V408Y319-L323 HydrophobicContact CD1-CD1 4.22Å; Y319-L323 HydrophobicContact CE1-CD1 3.89Å; Y319-L323 HydrophobicContact CE1-CG 4.35Å; Y319-L323 HydrophobicContact CE2-CD2 4.35Å; Y319-L323 HydrophobicContact CE2-CG 4.32Å; Y319-L323 PolarHBondContact O-N 3Å; Y320-L323 PolarHBondContact O-N 3.02Å; L323-A325 VanDerWaalsContact C-N 3.33Å; L323-A325 PolarHBondContact O-N 3.35Å; L323-W326 WeakPolarHBondContact O-CB 3.35Å; L323-W326 PolarHBondContact O-N 3.02Å; L323-W326 VanDerWaalsContact O-N 3.13Å; L323-L327 WeakPolarHBondContact O-CG 3.38Å; L323-L327 PolarHBondContact O-N 2.95Å; L323-W333 HydrophobicContact CD2-CZ3 4.02Å; L323-V343 HydrophobicContact CD1-CB 4.49Å; L323-V343 HydrophobicContact CD1-CG1 3.63Å; L323-V343 HydrophobicContact CD1-CG2 3.98Å; L323-V408 HydrophobicContact CB-CG2 4.03Å; L323-V408 HydrophobicContact CD1-CG2 4.19Å
324N94.5Very high93.6Very high8 Ų838.6 Ų38.64%0.04318%0.182CC..Hα-helixtrans-62.2-40.4175.5-81-78.5000111.8Y320 Y321 W326 L327 L328 F394 V407 L413Y320-N324 PolarHBondContact O-N 3.12Å; Y320-N324 PolarHBondContact O-ND2 3.22Å; Y321-N324 PolarHBondContact O-N 3.21Å; N324-W326 VanDerWaalsContact C-N 3.32Å; N324-L327 PolarHBondContact O-N 3.19Å; N324-L328 PolarHBondContact O-N 3.01Å; N324-F394 HydrophobicContact CB-CE2 4.24Å; N324-F394 HydrophobicContact CB-CZ 4.11Å; N324-V407 PolarHBondContact ND2-O 3.48Å; N324-L413 HydrophobicContact CB-CD1 4.29Å; N324-L413 HydrophobicContact CB-CD2 4.06Å
325A94.8Very high93.5Very high27 Ų2734.3 Ų34.322%0.22316%0.161CC..Hα-helixtrans-64.1-38.2172.900000111.8Y321 S322 L323 L327 L328 L329 L360Y321-A325 WeakPolarHBondContact O-CB 3.25Å; Y321-A325 PolarHBondContact O-N 3.12Å; S322-A325 PolarHBondContact O-N 3.2Å; L323-A325 VanDerWaalsContact C-N 3.33Å; L323-A325 PolarHBondContact O-N 3.35Å; A325-L327 VanDerWaalsContact C-N 3.35Å; A325-L328 PolarHBondContact O-N 3Å; A325-L329 WeakPolarHBondContact O-CG 3.49Å; A325-L329 PolarHBondContact O-N 3.25Å; A325-L360 HydrophobicContact CB-CD1 3.78Å
326W94.7Very high93.3Very high105 Ų10533.5 Ų33.540%0.39816%0.155SC..Hα-helixtrans-64-37.8174.3-173-106000112.3S322 L323 N324 L328 L329 C330 W356S322-W326 WeakPolarHBondContact O-CB 3.26Å; S322-W326 PolarHBondContact O-N 3.25Å; L323-W326 WeakPolarHBondContact O-CB 3.35Å; L323-W326 PolarHBondContact O-N 3.02Å; L323-W326 VanDerWaalsContact O-N 3.13Å; N324-W326 VanDerWaalsContact C-N 3.32Å; W326-L328 VanDerWaalsContact C-N 3.26Å; W326-L328 PolarHBondContact O-N 3.33Å; W326-L329 PolarHBondContact O-N 3.3Å; W326-C330 HydrophobicContact CD2-CB 4.17Å; W326-C330 HydrophobicContact CH2-CB 4.19Å; W326-C330 HydrophobicContact CZ2-CB 3.69Å; W326-C330 CarbonylContact O-C 3.43Å; W326-C330 WeakPolarHBondContact O-CA 3.48Å; W326-C330 PolarHBondContact O-N 3.5Å; W326-W356 HydrophobicContact CZ3-CZ3 4.48Å
327L94.4Very high93.1Very high2 Ų234.5 Ų34.51%0.0116%0.16CC..Hα-helixtrans-64-29.9174.1-67.8-174.2000113.2L323 N324 A325 P331 W333 L334 W338 V408 L413L323-L327 WeakPolarHBondContact O-CG 3.38Å; L323-L327 PolarHBondContact O-N 2.95Å; N324-L327 PolarHBondContact O-N 3.19Å; A325-L327 VanDerWaalsContact C-N 3.35Å; L327-P331 WeakPolarHBondContact O-CA 3.31Å; L327-P331 VanDerWaalsContact O-CB 3.31Å; L327-P331 WeakPolarHBondContact O-CB 3.31Å; L327-W333 VanDerWaalsContact CD2-O 3.25Å; L327-W333 WeakPolarHBondContact CD2-O 3.46Å; L327-L334 HydrophobicContact CD2-CD2 4.24Å; L327-W338 HydrophobicContact CD2-CZ2 4.4Å; L327-V408 HydrophobicContact CD1-CG1 3.34Å; L327-V408 HydrophobicContact CG-CG1 4.38Å; L327-L413 HydrophobicContact CB-CD1 3.94Å; L327-L413 HydrophobicContact CD1-CD1 4.24Å
328L95Very high92.9Very high9 Ų934.1 Ų34.15%0.04716%0.159CC..Hα-helixtrans-74-39.7172.5-67.3172.4000111.8H159 V161 N324 A325 W326 L390 L413 Y420H159-L328 PolarHBondContact NE2-O 3.26Å; V161-L328 HydrophobicContact CG1-CD2 4.35Å; N324-L328 PolarHBondContact O-N 3.01Å; A325-L328 PolarHBondContact O-N 3Å; W326-L328 VanDerWaalsContact C-N 3.26Å; W326-L328 PolarHBondContact O-N 3.33Å; L328-L390 HydrophobicContact CD1-CD1 3.74Å; L328-L413 HydrophobicContact CD2-CB 4.26Å; L328-L413 HydrophobicContact CD2-CD1 4.49Å; L328-L413 HydrophobicContact CG-CD1 4.34Å; L328-Y420 HydrophobicContact CB-CD1 4.35Å; L328-Y420 HydrophobicContact CB-CD2 4.09Å; L328-Y420 HydrophobicContact CB-CE2 4.42Å; L328-Y420 HydrophobicContact CB-CG 4.06Å; L328-Y420 WeakPolarHBondContact O-CE1 3.24Å; L328-Y420 VanDerWaalsContact O-CZ 3.23Å; L328-Y420 PolarHBondContact O-OH 3.28Å
329L93.8Very high92.5Very high105 Ų10533.5 Ų33.555%0.5516%0.156SC..Hα-helixtrans-77.9-39.9-177.9-71.2166.4000113.6A325 W326 Y420A325-L329 WeakPolarHBondContact O-CG 3.49Å; A325-L329 PolarHBondContact O-N 3.25Å; W326-L329 PolarHBondContact O-N 3.3Å; L329-Y420 HydrophobicContact CD2-CE2 3.74Å; L329-Y420 HydrophobicContact CG-CE2 4.33Å
330C93.6Very high92.1Very high45 Ų4534.1 Ų34.130%0.30416%0.16SC..  trans-140.981-174.9-171.80000109.6W326 W332W326-C330 HydrophobicContact CD2-CB 4.17Å; W326-C330 HydrophobicContact CH2-CB 4.19Å; W326-C330 HydrophobicContact CZ2-CB 3.69Å; W326-C330 CarbonylContact O-C 3.43Å; W326-C330 WeakPolarHBondContact O-CA 3.48Å; W326-C330 PolarHBondContact O-N 3.5Å; C330-W332 PolarHBondContact O-N 2.9Å
331P92.6Very high91.3Very high8 Ų836 Ų365%0.05218%0.181CC..THydrogen-bonded Turntrans-77.844.5-177.734.1-37.7000112.1P160 L327 L334 Y453P160-P331 HydrophobicContact CB-CB 3.95Å; P160-P331 HydrophobicContact CB-CG 4.04Å; P160-P331 HydrophobicContact CG-CB 4.18Å; P160-P331 HydrophobicContact CG-CG 3.7Å; L327-P331 WeakPolarHBondContact O-CA 3.31Å; L327-P331 VanDerWaalsContact O-CB 3.31Å; L327-P331 WeakPolarHBondContact O-CB 3.31Å; P331-L334 HydrophobicContact CB-CD1 4.4Å; P331-L334 HydrophobicContact CB-CD2 4.28Å; P331-L334 WeakPolarHBondContact O-CD1 3.37Å; P331-L334 WeakPolarHBondContact O-CG 3.42Å; P331-Y453 HydrophobicContact CG-CE1 4.36Å
332W88.4Confident90.7Very high157 Ų15735.1 Ų35.160%0.59518%0.18SC*.THydrogen-bonded Turntrans-84.2-34.9174.5-169.7-83.7000111.8C330 L334 R456C330-W332 PolarHBondContact O-N 2.9Å; W332-L334 PolarHBondContact O-N 3.23Å; W332-R456 VanDerWaalsContact CE2-NH1 3.33Å
333W88.5Confident90.3Very high85 Ų8534.9 Ų34.932%0.32218%0.178SC..SBendtrans-96.560.2-171-162.531000110.9L323 L327 W338 V477L323-W333 HydrophobicContact CD2-CZ3 4.02Å; L327-W333 VanDerWaalsContact CD2-O 3.25Å; L327-W333 WeakPolarHBondContact CD2-O 3.46Å; W333-W338 AromaticContact CD2-CH2 3.54Å; W333-W338 HydrophobicContact CD2-CH2 3.54Å; W333-W338 HydrophobicContact CD2-CZ3 4.15Å; W333-W338 AromaticContact CE2-CH2 3.72Å; W333-W338 AromaticContact CE2-CZ3 3.96Å; W333-W338 AromaticContact CE3-CH2 3.69Å; W333-W338 HydrophobicContact CE3-CH2 3.69Å; W333-W338 HydrophobicContact CE3-CZ3 4.12Å; W333-W338 HydrophobicContact CG-CH2 4.04Å; W333-W338 HydrophobicContact CH2-CH2 4.16Å; W333-W338 AromaticContact CH2-CZ3 3.77Å; W333-W338 HydrophobicContact CH2-CZ3 3.77Å; W333-W338 HydrophobicContact CZ2-CH2 4.03Å; W333-W338 AromaticContact CZ2-CZ3 3.78Å; W333-W338 HydrophobicContact CZ2-CZ3 3.78Å; W333-W338 AromaticContact CZ3-CH2 4Å; W333-W338 HydrophobicContact CZ3-CH2 4Å; W333-W338 AromaticContact CZ3-CZ3 3.94Å; W333-W338 HydrophobicContact CZ3-CZ3 3.94Å; W333-W338 WeakPolarHBondContact O-CZ2 3.39Å; W333-V477 PolarHBondContact NE1-O 3.46Å
334L91.9Very high90.1Very high11 Ų1137.7 Ų37.76%0.05820%0.197CC..  trans-94.3128.4-176.9-64.2178.4000110.7P160 L327 P331 W332 E410 R460P160-L334 HydrophobicContact CB-CD1 3.98Å; L327-L334 HydrophobicContact CD2-CD2 4.24Å; P331-L334 HydrophobicContact CB-CD1 4.4Å; P331-L334 HydrophobicContact CB-CD2 4.28Å; P331-L334 WeakPolarHBondContact O-CD1 3.37Å; P331-L334 WeakPolarHBondContact O-CG 3.42Å; W332-L334 PolarHBondContact O-N 3.23Å; L334-E410 WeakPolarHBondContact CB-OE1 3.47Å; L334-E410 HydrophobicContact CD2-CG 3.86Å; L334-R460 HydrophobicContact CD1-CG 3.98Å
335C91.6Very high89.9Confident0 Ų038.5 Ų38.50%020%0.201CC..  trans-134.7144.7-179.9-169.10000110.2D337 W338 E410 V477 C478C335-D337 PolarHBondContact O-N 2.99Å; C335-D337 PolarHBondContact SG-O 3.49Å; C335-W338 HydrophobicContact CB-CD2 4.46Å; C335-W338 HydrophobicContact CB-CZ2 4.1Å; C335-W338 PolarHBondContact O-NE1 3.45Å; C335-E410 PolarHBondContact N-OE1 3.41Å; C335-V477 HydrophobicContact CB-CG2 3.97Å; C335-C478 VanDerWaalsContact SG-SG 3.62Å
336F90.3Very high89.9Confident9 Ų937.4 Ų37.44%0.03919%0.192CC..SBendtrans-71.3-20.5178.275.8-90.3000112.3F44 R460 W464 L470 F471 A474 V484F44-F336 HydrophobicContact CD1-CD2 4.01Å; F44-F336 AromaticContact CD2-CD2 3.8Å; F44-F336 HydrophobicContact CD2-CD2 3.8Å; F44-F336 AromaticContact CD2-CE2 3.78Å; F44-F336 HydrophobicContact CD2-CE2 3.78Å; F44-F336 AromaticContact CE1-CD2 3.76Å; F44-F336 HydrophobicContact CE1-CD2 3.76Å; F44-F336 HydrophobicContact CE1-CE2 4.42Å; F44-F336 AromaticContact CE2-CD2 3.54Å; F44-F336 HydrophobicContact CE2-CD2 3.54Å; F44-F336 AromaticContact CE2-CE2 3.37Å; F44-F336 HydrophobicContact CE2-CE2 3.37Å; F44-F336 HydrophobicContact CG-CD2 4.03Å; F44-F336 HydrophobicContact CG-CE2 4.46Å; F44-F336 AromaticContact CZ-CD2 3.51Å; F44-F336 HydrophobicContact CZ-CD2 3.51Å; F44-F336 AromaticContact CZ-CE2 3.74Å; F44-F336 HydrophobicContact CZ-CE2 3.74Å; F336-R460 VanDerWaalsContact N-NH2 3.2Å; F336-W464 HydrophobicContact CB-CH2 4.16Å; F336-W464 HydrophobicContact CB-CZ2 4.05Å; F336-L470 HydrophobicContact CB-CD1 3.98Å; F336-L470 HydrophobicContact CB-CD2 4.27Å; F336-L470 HydrophobicContact CB-CG 4.17Å; F336-L470 HydrophobicContact CD1-CD1 4.46Å; F336-L470 HydrophobicContact CD1-CG 4.13Å; F336-L470 HydrophobicContact CG-CD1 4.48Å; F336-L470 HydrophobicContact CG-CD2 4.41Å; F336-L470 HydrophobicContact CG-CG 4.2Å; F336-F471 HydrophobicContact CD1-CD1 4.11Å; F336-F471 HydrophobicContact CD2-CD1 4.46Å; F336-F471 HydrophobicContact CD2-CE1 4.24Å; F336-F471 AromaticContact CE1-CD1 3.51Å; F336-F471 HydrophobicContact CE1-CD1 3.51Å; F336-F471 HydrophobicContact CE1-CE1 4.2Å; F336-F471 HydrophobicContact CE1-CG 4.47Å; F336-F471 AromaticContact CE2-CD1 3.93Å; F336-F471 HydrophobicContact CE2-CD1 3.93Å; F336-F471 AromaticContact CE2-CE1 3.78Å; F336-F471 HydrophobicContact CE2-CE1 3.78Å; F336-F471 AromaticContact CZ-CD1 3.42Å; F336-F471 HydrophobicContact CZ-CD1 3.42Å; F336-F471 VanDerWaalsContact CZ-CD1 3.42Å; F336-F471 AromaticContact CZ-CE1 3.77Å; F336-F471 HydrophobicContact CZ-CE1 3.77Å; F336-F471 HydrophobicContact CZ-CG 4.44Å; F336-A474 HydrophobicContact CD1-CB 3.72Å; F336-A474 HydrophobicContact CE1-CB 3.43Å; F336-A474 VanDerWaalsContact CE1-CB 3.43Å; F336-V484 HydrophobicContact CE1-CG2 3.94Å; F336-V484 HydrophobicContact CZ-CG2 4.03Å
337D89.7Confident89.9Confident21 Ų2139.4 Ų39.411%0.11220%0.203CC..  trans-152.9132.9-179.1-162.4-27.4000111.9F44 C335 S339 N481 K483F44-D337 HydrophobicContact CZ-CB 4.39Å; C335-D337 PolarHBondContact O-N 2.99Å; C335-D337 PolarHBondContact SG-O 3.49Å; D337-S339 VanDerWaalsContact CG-OG 3.24Å; D337-S339 VanDerWaalsContact OD1-CB 3.23Å; D337-S339 WeakPolarHBondContact OD1-CB 3.41Å; D337-S339 PolarHBondContact OD1-N 3.42Å; D337-S339 PolarHBondContact OD1-OG 3.33Å; D337-S339 PolarHBondContact OD2-OG 3.49Å; D337-N481 PolarHBondContact O-ND2 2.91Å; D337-K483 VanDerWaalsContact OD2-CD 3.26Å; D337-K483 WeakPolarHBondContact OD2-CD 3.34Å; D337-K483 WeakPolarHBondContact OD2-CE 3.47Å; D337-K483 IonicContact OD2-NZ 2.89Å; D337-K483 PolarHBondContact OD2-NZ 3.04Å
338W89.1Confident89.8Confident13 Ų1342 Ų425%0.04922%0.221CC..  trans-113.411.8-179-67.584.6000113.6L327 W333 C335 C342 V343 V408L327-W338 HydrophobicContact CD2-CZ2 4.4Å; W333-W338 AromaticContact CD2-CH2 3.54Å; W333-W338 HydrophobicContact CD2-CH2 3.54Å; W333-W338 HydrophobicContact CD2-CZ3 4.15Å; W333-W338 AromaticContact CE2-CH2 3.72Å; W333-W338 AromaticContact CE2-CZ3 3.96Å; W333-W338 AromaticContact CE3-CH2 3.69Å; W333-W338 HydrophobicContact CE3-CH2 3.69Å; W333-W338 HydrophobicContact CE3-CZ3 4.12Å; W333-W338 HydrophobicContact CG-CH2 4.04Å; W333-W338 HydrophobicContact CH2-CH2 4.16Å; W333-W338 AromaticContact CH2-CZ3 3.77Å; W333-W338 HydrophobicContact CH2-CZ3 3.77Å; W333-W338 HydrophobicContact CZ2-CH2 4.03Å; W333-W338 AromaticContact CZ2-CZ3 3.78Å; W333-W338 HydrophobicContact CZ2-CZ3 3.78Å; W333-W338 AromaticContact CZ3-CH2 4Å; W333-W338 HydrophobicContact CZ3-CH2 4Å; W333-W338 AromaticContact CZ3-CZ3 3.94Å; W333-W338 HydrophobicContact CZ3-CZ3 3.94Å; W333-W338 WeakPolarHBondContact O-CZ2 3.39Å; C335-W338 HydrophobicContact CB-CD2 4.46Å; C335-W338 HydrophobicContact CB-CZ2 4.1Å; C335-W338 PolarHBondContact O-NE1 3.45Å; W338-C342 HydrophobicContact CE3-CB 4.23Å; W338-C342 WeakPolarHBondContact O-CB 3.18Å; W338-V343 HydrophobicContact CE3-CG2 3.98Å; W338-V343 HydrophobicContact CZ3-CG2 4.48Å; W338-V408 HydrophobicContact CB-CB 4.16Å; W338-V408 HydrophobicContact CD2-CB 3.91Å; W338-V408 HydrophobicContact CD2-CG1 4.03Å; W338-V408 HydrophobicContact CE3-CB 4.43Å; W338-V408 HydrophobicContact CG-CB 3.78Å; W338-V408 HydrophobicContact CG-CG1 4.21Å; W338-V408 HydrophobicContact CZ2-CG1 4.23Å
339S88.1Confident89.5Confident10 Ų1045.9 Ų45.97%0.0726%0.255CS..  trans-75.9-175.617562.40000112.6D337 G341 C342 N481D337-S339 VanDerWaalsContact CG-OG 3.24Å; D337-S339 VanDerWaalsContact OD1-CB 3.23Å; D337-S339 WeakPolarHBondContact OD1-CB 3.41Å; D337-S339 PolarHBondContact OD1-N 3.42Å; D337-S339 PolarHBondContact OD1-OG 3.33Å; D337-S339 PolarHBondContact OD2-OG 3.49Å; S339-G341 PolarHBondContact O-N 3.47Å; S339-C342 PolarHBondContact O-N 3.18Å; S339-C342 PolarHBondContact O-SG 2.89Å; S339-N481 PolarHBondContact O-ND2 3.46Å
340M86.6Confident89.4Confident32 Ų3247 Ų4716%0.15827%0.266CS..THydrogen-bonded Turntrans59.443.8168.6-68-93.4-172.300113.8V300 A482 K483 H512 Y515V300-M340 HydrophobicContact CG1-CB 4.25Å; V300-M340 HydrophobicContact CG1-CE 3.56Å; V300-M340 HydrophobicContact CG1-CG 3.45Å; V300-M340 VanDerWaalsContact CG1-CG 3.45Å; V300-M340 HydrophobicContact CG1-SD 3.24Å; V300-M340 WeakPolarHBondContact CG1-SD 3.48Å; V300-M340 PolarHBondContact O-N 3.13Å; M340-A482 HydrophobicContact CB-CB 4.33Å; M340-A482 HydrophobicContact SD-CB 4.31Å; M340-K483 HydrophobicContact CB-CB 4.37Å; M340-K483 HydrophobicContact CG-CB 3.91Å; M340-H512 HydrophobicContact SD-CB 4.39Å; M340-Y515 HydrophobicContact CE-CD1 4.48Å; M340-Y515 HydrophobicContact CE-CD2 4.19Å; M340-Y515 HydrophobicContact CE-CE1 4.18Å; M340-Y515 HydrophobicContact CE-CE2 3.87Å; M340-Y515 HydrophobicContact CE-CG 4.49Å; M340-Y515 HydrophobicContact SD-CE1 4.48Å
341G75.2Confident89.5Confident44 Ų4446.5 Ų46.545%0.45426%0.26SS..THydrogen-bonded Turntrans83.312.4171.400000115.6S339 V343S339-G341 PolarHBondContact O-N 3.47Å; G341-V343 PolarHBondContact O-N 3.12Å
342C82.9Confident89.6Confident18 Ų1854.2 Ų54.212%0.12229%0.289CS..SBendtrans-56.8-36.7176.3-71.80000113.7W338 S339 P344 N481W338-C342 HydrophobicContact CE3-CB 4.23Å; W338-C342 WeakPolarHBondContact O-CB 3.18Å; S339-C342 PolarHBondContact O-N 3.18Å; S339-C342 PolarHBondContact O-SG 2.89Å; C342-P344 WeakPolarHBondContact O-CD 3.34Å; C342-N481 WeakPolarHBondContact SG-CB 3.33Å; C342-N481 PolarHBondContact SG-ND2 2.94Å
343V87.5Confident90Very high9 Ų948.2 Ų48.26%0.05527%0.266CS..SBendtrans-118.693-177.4-1700000108.5Y319 Y320 L323 W338 G341Y319-V343 HydrophobicContact CD1-CG1 3.97Å; Y319-V343 HydrophobicContact CE1-CG1 3.66Å; Y320-V343 HydrophobicContact CD1-CG1 4.12Å; Y320-V343 HydrophobicContact CE1-CB 4.18Å; Y320-V343 HydrophobicContact CE1-CG1 3.68Å; L323-V343 HydrophobicContact CD1-CB 4.49Å; L323-V343 HydrophobicContact CD1-CG1 3.63Å; L323-V343 HydrophobicContact CD1-CG2 3.98Å; W338-V343 HydrophobicContact CE3-CG2 3.98Å; W338-V343 HydrophobicContact CZ3-CG2 4.48Å; G341-V343 PolarHBondContact O-N 3.12Å
344P88.3Confident90.3Very high73 Ų7345.7 Ų45.747%0.47426%0.26SS..  trans-61.1148.1178.8-22.432.5000111.4C342 R353C342-P344 WeakPolarHBondContact O-CD 3.34Å; P344-R353 PolarHBondContact O-NH1 2.92Å
345L91.8Very high90.4Very high26 Ų2649.5 Ų49.514%0.13628%0.283CS..  trans-69.7142178.9-63.5173.2000112P303 A304 E307 N316 K347 R353P303-L345 HydrophobicContact CB-CD1 4.12Å; P303-L345 HydrophobicContact CB-CD2 4.22Å; P303-L345 HydrophobicContact CB-CG 4.23Å; P303-L345 HydrophobicContact CG-CD2 4.19Å; P303-L345 HydrophobicContact CG-CG 4.42Å; A304-L345 HydrophobicContact CB-CD2 3.73Å; E307-L345 HydrophobicContact CG-CD1 3.42Å; E307-L345 VanDerWaalsContact CG-CD1 3.42Å; E307-L345 WeakPolarHBondContact OE1-CD1 3.34Å; N316-L345 HydrophobicContact CB-CD2 4.14Å; N316-L345 WeakPolarHBondContact OD1-CA 3.42Å; L345-K347 HydrophobicContact CB-CG 4.36Å; L345-R353 PolarHBondContact O-NH2 2.86Å
346I94.3Very high90.5Very high4 Ų453.8 Ų53.82%0.02130%0.3CS..  trans-82112.2165.8-62.3174.5000107.1V315 N316 Y319 S348 D351 R353 V354 L357V315-I346 HydrophobicContact CG1-CB 4.2Å; V315-I346 HydrophobicContact CG1-CD1 4.48Å; V315-I346 HydrophobicContact CG1-CG2 3.95Å; N316-I346 PolarHBondContact ND2-O 3.41Å; N316-I346 PolarHBondContact OD1-N 3.47Å; Y319-I346 HydrophobicContact CD1-CD1 3.9Å; Y319-I346 HydrophobicContact CD1-CG1 4.38Å; Y319-I346 HydrophobicContact CD2-CD1 3.99Å; Y319-I346 HydrophobicContact CE1-CD1 4.46Å; Y319-I346 HydrophobicContact CG-CD1 3.63Å; I346-S348 WeakPolarHBondContact CG2-O 3.34Å; I346-D351 HydrophobicContact CG2-CB 3.9Å; I346-R353 HydrophobicContact CD1-CB 3.74Å; I346-R353 HydrophobicContact CG1-CB 4.21Å; I346-V354 HydrophobicContact CG2-CG2 3.89Å; I346-L357 HydrophobicContact CD1-CD1 4.39Å
347K93.7Very high90.7Very high146 Ų14654.1 Ų54.164%0.63530%0.301SS*.  trans-106.8-12.8-179.9-65.8-170.7174.2-168.20113.9E307 L345E307-K347 WeakPolarHBondContact OE1-CE 3.5Å; E307-K347 IonicContact OE1-NZ 2.75Å; L345-K347 HydrophobicContact CB-CG 4.36Å
348S93.1Very high91Very high57 Ų5758.4 Ų58.440%0.39932%0.324SS..  trans-130.2146.7-178.3-1790000111.3I346 T350 D351I346-S348 WeakPolarHBondContact CG2-O 3.34Å; S348-T350 PolarHBondContact O-N 3.06Å; S348-T350 PolarHBondContact OG-N 3.07Å; S348-T350 PolarHBondContact OG-OG1 2.68Å; S348-D351 VanDerWaalsContact O-CB 3.27Å; S348-D351 WeakPolarHBondContact O-CB 3.47Å; S348-D351 PolarHBondContact O-N 3.4Å
349A88.5Confident91.3Very high90 Ų9062 Ų6274%0.74434%0.344SS*.THydrogen-bonded Turntrans-68.7-18.8171.800000113D351A349-D351 PolarHBondContact O-N 3.36Å
350T92.8Very high91.6Very high130 Ų13062.8 Ų62.880%0.79835%0.347SS*.THydrogen-bonded Turntrans-80.3-4.3175.257.90000113.4S348 W352S348-T350 PolarHBondContact O-N 3.06Å; S348-T350 PolarHBondContact OG-N 3.07Å; S348-T350 PolarHBondContact OG-OG1 2.68Å; T350-W352 PolarHBondContact O-N 3.37Å
351D95.4Very high92Very high33 Ų3366.9 Ų66.918%0.17636%0.361CS..  trans-66.6122175.5-166.5-42.7000109.8I346 S348 A349 R353 V354I346-D351 HydrophobicContact CG2-CB 3.9Å; S348-D351 VanDerWaalsContact O-CB 3.27Å; S348-D351 WeakPolarHBondContact O-CB 3.47Å; S348-D351 PolarHBondContact O-N 3.4Å; A349-D351 PolarHBondContact O-N 3.36Å; D351-R353 PolarHBondContact O-N 3.25Å; D351-R353 VanDerWaalsContact OD1-CB 3.27Å; D351-R353 WeakPolarHBondContact OD1-CB 3.34Å; D351-R353 VanDerWaalsContact OD1-CG 3.27Å; D351-R353 WeakPolarHBondContact OD1-CG 3.39Å; D351-R353 IonicContact OD1-CZ 3.36Å; D351-R353 PolarHBondContact OD1-N 3.46Å; D351-R353 IonicContact OD1-NE 3.56Å; D351-R353 PolarHBondContact OD1-NE 3.15Å; D351-R353 IonicContact OD2-CZ 2.95Å; D351-R353 VanDerWaalsContact OD2-CZ 3.31Å; D351-R353 IonicContact OD2-NE 3.21Å; D351-R353 PolarHBondContact OD2-NE 3.23Å; D351-R353 VanDerWaalsContact OD2-NE 3.14Å; D351-R353 IonicContact OD2-NH2 3.55Å; D351-R353 PolarHBondContact OD2-NH2 3.46Å; D351-V354 HydrophobicContact CB-CG2 4.44Å; D351-V354 WeakPolarHBondContact O-CB 3.09Å; D351-V354 WeakPolarHBondContact O-CG2 3.46Å; D351-V354 PolarHBondContact O-N 3.16Å
352W94.8Very high93.1Very high171 Ų17169 Ų6965%0.64837%0.367SS*.THydrogen-bonded Turntrans-57-24.5-17873.6-87.9000112.8T350 V354 V355 W356T350-W352 PolarHBondContact O-N 3.37Å; W352-V354 PolarHBondContact O-N 3.19Å; W352-V355 WeakPolarHBondContact O-CB 3.32Å; W352-V355 WeakPolarHBondContact O-CG2 3.41Å; W352-V355 PolarHBondContact O-N 2.88Å; W352-V355 VanDerWaalsContact O-N 3.12Å; W352-W356 AromaticContact CE3-NE1 3.92Å; W352-W356 AromaticContact CH2-NE1 3.7Å; W352-W356 AromaticContact CZ3-CD1 4Å; W352-W356 HydrophobicContact CZ3-CZ2 4.36Å; W352-W356 AromaticContact CZ3-NE1 3.11Å
353R95.3Very high93.6Very high30 Ų3071.8 Ų71.811%0.11338%0.384CS..THydrogen-bonded Turntrans-63.7-22179.1-64.2177.4-69.8164.82.4112.7Y319 P344 L345 I346 D351 V355 W356 L357Y319-R353 HydrophobicContact CD2-CB 4.42Å; Y319-R353 HydrophobicContact CE2-CB 3.87Å; Y319-R353 HydrophobicContact CE2-CG 4.39Å; Y319-R353 WeakPolarHBondContact OH-CD 3.45Å; P344-R353 PolarHBondContact O-NH1 2.92Å; L345-R353 PolarHBondContact O-NH2 2.86Å; I346-R353 HydrophobicContact CD1-CB 3.74Å; I346-R353 HydrophobicContact CG1-CB 4.21Å; D351-R353 PolarHBondContact O-N 3.25Å; D351-R353 VanDerWaalsContact OD1-CB 3.27Å; D351-R353 WeakPolarHBondContact OD1-CB 3.34Å; D351-R353 VanDerWaalsContact OD1-CG 3.27Å; D351-R353 WeakPolarHBondContact OD1-CG 3.39Å; D351-R353 IonicContact OD1-CZ 3.36Å; D351-R353 PolarHBondContact OD1-N 3.46Å; D351-R353 IonicContact OD1-NE 3.56Å; D351-R353 PolarHBondContact OD1-NE 3.15Å; D351-R353 IonicContact OD2-CZ 2.95Å; D351-R353 VanDerWaalsContact OD2-CZ 3.31Å; D351-R353 IonicContact OD2-NE 3.21Å; D351-R353 PolarHBondContact OD2-NE 3.23Å; D351-R353 VanDerWaalsContact OD2-NE 3.14Å; D351-R353 IonicContact OD2-NH2 3.55Å; D351-R353 PolarHBondContact OD2-NH2 3.46Å; R353-V355 PolarHBondContact O-N 3.28Å; R353-W356 WeakPolarHBondContact O-CB 3.15Å; R353-W356 PolarHBondContact O-N 2.9Å; R353-W356 VanDerWaalsContact O-N 3.12Å; R353-L357 WeakPolarHBondContact O-CD1 3.38Å
354V94.9Very high94Very high32 Ų3273.1 Ų73.119%0.19439%0.39CS..Hα-helixtrans-58.3-29.3174.3175.70000111.8I346 D351 W352 W356 L357 L358I346-V354 HydrophobicContact CG2-CG2 3.89Å; D351-V354 HydrophobicContact CB-CG2 4.44Å; D351-V354 WeakPolarHBondContact O-CB 3.09Å; D351-V354 WeakPolarHBondContact O-CG2 3.46Å; D351-V354 PolarHBondContact O-N 3.16Å; W352-V354 PolarHBondContact O-N 3.19Å; V354-W356 PolarHBondContact O-N 3.5Å; V354-L357 WeakPolarHBondContact O-CB 3.42Å; V354-L357 PolarHBondContact O-N 3.4Å; V354-L358 PolarHBondContact O-N 3.25Å
355V94.9Very high94.3Very high91 Ų9174.8 Ų74.855%0.55239%0.394SS*.Hα-helixtrans-57.3-35.4177.1176.70000111.8W352 R353 L357 L358 L359W352-V355 WeakPolarHBondContact O-CB 3.32Å; W352-V355 WeakPolarHBondContact O-CG2 3.41Å; W352-V355 PolarHBondContact O-N 2.88Å; W352-V355 VanDerWaalsContact O-N 3.12Å; R353-V355 PolarHBondContact O-N 3.28Å; V355-L357 VanDerWaalsContact C-N 3.32Å; V355-L357 PolarHBondContact O-N 2.89Å; V355-L358 PolarHBondContact O-N 2.91Å; V355-L359 WeakPolarHBondContact O-CB 3.49Å; V355-L359 PolarHBondContact O-N 3.4Å
356W94.7Very high94.4Very high91 Ų9175.2 Ų75.235%0.34541%0.405SS..Hα-helixtrans-66.6-33.1178.6-64.7114.7000113.1S322 W326 W352 R353 V354 L359 L360S322-W356 PolarHBondContact OG-O 3.02Å; W326-W356 HydrophobicContact CZ3-CZ3 4.48Å; W352-W356 AromaticContact CE3-NE1 3.92Å; W352-W356 AromaticContact CH2-NE1 3.7Å; W352-W356 AromaticContact CZ3-CD1 4Å; W352-W356 HydrophobicContact CZ3-CZ2 4.36Å; W352-W356 AromaticContact CZ3-NE1 3.11Å; R353-W356 WeakPolarHBondContact O-CB 3.15Å; R353-W356 PolarHBondContact O-N 2.9Å; R353-W356 VanDerWaalsContact O-N 3.12Å; V354-W356 PolarHBondContact O-N 3.5Å; W356-L359 HydrophobicContact CE3-CD2 3.86Å; W356-L359 HydrophobicContact CZ3-CD2 3.79Å; W356-L359 PolarHBondContact O-N 3.35Å; W356-L360 WeakPolarHBondContact O-CB 3.4Å; W356-L360 PolarHBondContact O-N 3.39Å
357L94.4Very high94.3Very high15 Ų1577.4 Ų77.48%0.07942%0.416CS..Hα-helixtrans-69.2-45.1177.6-69.358.6000109.6V315 N318 Y319 I346 R353 V354 V355 L359 L360 W361V315-L357 HydrophobicContact CG1-CD2 3.81Å; V315-L357 WeakPolarHBondContact O-CD2 3.48Å; N318-L357 HydrophobicContact CB-CD2 3.98Å; N318-L357 HydrophobicContact CB-CG 4.06Å; Y319-L357 HydrophobicContact CD2-CD1 3.57Å; Y319-L357 HydrophobicContact CG-CD1 4.1Å; I346-L357 HydrophobicContact CD1-CD1 4.39Å; R353-L357 WeakPolarHBondContact O-CD1 3.38Å; V354-L357 WeakPolarHBondContact O-CB 3.42Å; V354-L357 PolarHBondContact O-N 3.4Å; V355-L357 VanDerWaalsContact C-N 3.32Å; V355-L357 PolarHBondContact O-N 2.89Å; L357-L359 VanDerWaalsContact C-N 3.34Å; L357-L360 PolarHBondContact O-N 3.02Å; L357-W361 VanDerWaalsContact O-CD1 3.27Å; L357-W361 PolarHBondContact O-N 2.74Å
358L94.3Very high94.2Very high111 Ų11173.5 Ų73.558%0.58141%0.405SS*.Hα-helixtrans-60.5-46.7176.2-62.7177000110.2V354 V355 L360 W361 C362V354-L358 PolarHBondContact O-N 3.25Å; V355-L358 PolarHBondContact O-N 2.91Å; L358-L360 PolarHBondContact O-N 3.26Å; L358-W361 PolarHBondContact O-N 3.1Å; L358-C362 VanDerWaalsContact O-CB 3.32Å; L358-C362 WeakPolarHBondContact O-CB 3.46Å; L358-C362 PolarHBondContact O-N 3.07Å; L358-C362 PolarHBondContact O-SG 3.22Å
359L95.8Very high94Very high90 Ų9073.5 Ų73.547%0.47141%0.405SS..Hα-helixtrans-60.1-46.3177.5-176.964.1000112V355 W356 L357 W361 C362 V363V355-L359 WeakPolarHBondContact O-CB 3.49Å; V355-L359 PolarHBondContact O-N 3.4Å; W356-L359 HydrophobicContact CE3-CD2 3.86Å; W356-L359 HydrophobicContact CZ3-CD2 3.79Å; W356-L359 PolarHBondContact O-N 3.35Å; L357-L359 VanDerWaalsContact C-N 3.34Å; L359-W361 PolarHBondContact O-N 3.09Å; L359-C362 PolarHBondContact O-N 2.88Å; L359-V363 HydrophobicContact CD1-CG2 4.28Å; L359-V363 VanDerWaalsContact O-CG2 3.24Å; L359-V363 WeakPolarHBondContact O-CG2 3.49Å; L359-V363 PolarHBondContact O-N 2.91Å
360L95.5Very high94Very high25 Ų2573 Ų7313%0.13139%0.387CS..Hα-helixtrans-55.4-53.2177.1175.570.7000110.8S322 A325 W356 L357 L358 V363 L364S322-L360 WeakPolarHBondContact OG-CD2 3.41Å; A325-L360 HydrophobicContact CB-CD1 3.78Å; W356-L360 WeakPolarHBondContact O-CB 3.4Å; W356-L360 PolarHBondContact O-N 3.39Å; L357-L360 PolarHBondContact O-N 3.02Å; L358-L360 PolarHBondContact O-N 3.26Å; L360-V363 PolarHBondContact O-N 2.89Å; L360-L364 HydrophobicContact CD1-CD1 3.93Å; L360-L364 HydrophobicContact CD1-CG 4.26Å; L360-L364 HydrophobicContact CD2-CD1 4.5Å; L360-L364 HydrophobicContact CG-CD1 3.91Å; L360-L364 HydrophobicContact CG-CG 4.5Å; L360-L364 WeakPolarHBondContact O-CB 3.1Å; L360-L364 WeakPolarHBondContact O-CG 3.45Å; L360-L364 PolarHBondContact O-N 2.85Å
361W95.4Very high93.7Very high119 Ų11966.9 Ų66.945%0.45135%0.35SS..Hα-helixtrans-69.7-36.8-177.3-77.3109.6000112.6N318 L357 L358 L359 V363 L364 I365N318-W361 VanDerWaalsContact OD1-CE2 3.3Å; N318-W361 VanDerWaalsContact OD1-CZ2 3.28Å; N318-W361 WeakPolarHBondContact OD1-CZ2 3.25Å; N318-W361 PolarHBondContact OD1-NE1 3.05Å; L357-W361 VanDerWaalsContact O-CD1 3.27Å; L357-W361 PolarHBondContact O-N 2.74Å; L358-W361 PolarHBondContact O-N 3.1Å; L359-W361 PolarHBondContact O-N 3.09Å; W361-V363 VanDerWaalsContact C-N 3.33Å; W361-V363 PolarHBondContact O-N 3.23Å; W361-L364 HydrophobicContact CE3-CB 4.5Å; W361-L364 HydrophobicContact CE3-CD1 4.37Å; W361-L364 HydrophobicContact CZ3-CD1 4.47Å; W361-L364 PolarHBondContact O-N 2.87Å; W361-I365 HydrophobicContact CB-CD1 4.44Å; W361-I365 VanDerWaalsContact O-CB 3.22Å; W361-I365 WeakPolarHBondContact O-CB 3.26Å; W361-I365 WeakPolarHBondContact O-CD1 3.4Å; W361-I365 WeakPolarHBondContact O-CG1 3.32Å; W361-I365 PolarHBondContact O-N 2.91Å
362C96.7Very high93Very high87 Ų8768 Ų6859%0.58836%0.355SS*.Hα-helixtrans-58.3-45.4172.4-74.40000111.6L358 L359 G366L358-C362 VanDerWaalsContact O-CB 3.32Å; L358-C362 WeakPolarHBondContact O-CB 3.46Å; L358-C362 PolarHBondContact O-N 3.07Å; L358-C362 PolarHBondContact O-SG 3.22Å; L359-C362 PolarHBondContact O-N 2.88Å; C362-G366 PolarHBondContact O-N 3.49Å
363V95Very high92.4Very high77 Ų7763 Ų6347%0.46735%0.346SS..Hα-helixtrans-67-46.8177.8173.10000111L359 L360 W361 G366 L367L359-V363 HydrophobicContact CD1-CG2 4.28Å; L359-V363 VanDerWaalsContact O-CG2 3.24Å; L359-V363 WeakPolarHBondContact O-CG2 3.49Å; L359-V363 PolarHBondContact O-N 2.91Å; L360-V363 PolarHBondContact O-N 2.89Å; W361-V363 VanDerWaalsContact C-N 3.33Å; W361-V363 PolarHBondContact O-N 3.23Å; V363-G366 PolarHBondContact O-N 3.42Å; V363-L367 HydrophobicContact CG1-CD1 3.98Å; V363-L367 HydrophobicContact CG1-CG 4.38Å; V363-L367 WeakPolarHBondContact O-CG 3.35Å; V363-L367 PolarHBondContact O-N 3.48Å
364L94.4Very high91.8Very high38 Ų3861.9 Ų61.920%0.19934%0.342CS..Hα-helixtrans-63.2-45.5179.5-74.6176.5000111.9L360 W361 G366 L367 V368 L387L360-L364 HydrophobicContact CD1-CD1 3.93Å; L360-L364 HydrophobicContact CD1-CG 4.26Å; L360-L364 HydrophobicContact CD2-CD1 4.5Å; L360-L364 HydrophobicContact CG-CD1 3.91Å; L360-L364 HydrophobicContact CG-CG 4.5Å; L360-L364 WeakPolarHBondContact O-CB 3.1Å; L360-L364 WeakPolarHBondContact O-CG 3.45Å; L360-L364 PolarHBondContact O-N 2.85Å; W361-L364 HydrophobicContact CE3-CB 4.5Å; W361-L364 HydrophobicContact CE3-CD1 4.37Å; W361-L364 HydrophobicContact CZ3-CD1 4.47Å; W361-L364 PolarHBondContact O-N 2.87Å; L364-G366 VanDerWaalsContact C-N 3.3Å; L364-G366 PolarHBondContact O-N 3.11Å; L364-L367 PolarHBondContact O-N 2.82Å; L364-V368 WeakPolarHBondContact O-CB 3.36Å; L364-V368 VanDerWaalsContact O-CG2 3.23Å; L364-V368 WeakPolarHBondContact O-CG2 3.49Å; L364-V368 PolarHBondContact O-N 3.17Å; L364-L387 HydrophobicContact CD2-CD2 4.48Å
365I94.6Very high90.8Very high107 Ų10766.5 Ų66.555%0.54937%0.373SS..Hα-helixtrans-60.8-42.8175.8-69.1165.4000110.1W361 V368 S369W361-I365 HydrophobicContact CB-CD1 4.44Å; W361-I365 VanDerWaalsContact O-CB 3.22Å; W361-I365 WeakPolarHBondContact O-CB 3.26Å; W361-I365 WeakPolarHBondContact O-CD1 3.4Å; W361-I365 WeakPolarHBondContact O-CG1 3.32Å; W361-I365 PolarHBondContact O-N 2.91Å; I365-V368 PolarHBondContact O-N 2.89Å; I365-S369 WeakPolarHBondContact O-CB 3.46Å; I365-S369 PolarHBondContact O-N 3.4Å
366G93.5Very high90.2Very high35 Ų3565.1 Ų65.136%0.36136%0.363SS..Hα-helixtrans-59.9-46.8174.800000112.7C362 V363 L364 S369 Q370C362-G366 PolarHBondContact O-N 3.49Å; V363-G366 PolarHBondContact O-N 3.42Å; L364-G366 VanDerWaalsContact C-N 3.3Å; L364-G366 PolarHBondContact O-N 3.11Å; G366-S369 PolarHBondContact O-N 3.27Å; G366-Q370 VanDerWaalsContact O-CG 3.28Å; G366-Q370 WeakPolarHBondContact O-CG 3.44Å; G366-Q370 PolarHBondContact O-N 2.54Å
367L92.6Very high89.3Confident50 Ų5062.7 Ų62.726%0.26236%0.36SS..Hα-helixtrans-64.7-44.2177.5-72.9173.4000112.1V363 L364 Q370 A371 L387V363-L367 HydrophobicContact CG1-CD1 3.98Å; V363-L367 HydrophobicContact CG1-CG 4.38Å; V363-L367 WeakPolarHBondContact O-CG 3.35Å; V363-L367 PolarHBondContact O-N 3.48Å; L364-L367 PolarHBondContact O-N 2.82Å; L367-Q370 PolarHBondContact O-N 3.05Å; L367-A371 VanDerWaalsContact O-CB 3.22Å; L367-A371 WeakPolarHBondContact O-CB 3.36Å; L367-A371 PolarHBondContact O-N 3.01Å; L367-L387 HydrophobicContact CB-CD1 4.3Å; L367-L387 HydrophobicContact CB-CD2 4.23Å; L367-L387 HydrophobicContact CD1-CD2 4.39Å
368V91.3Very high88.5Confident65 Ų6563.1 Ų63.139%0.39436%0.361SS..Hα-helixtrans-63.1-44.2176.9170.30000110.5L364 I365 Q370 A371 L372 L387L364-V368 WeakPolarHBondContact O-CB 3.36Å; L364-V368 VanDerWaalsContact O-CG2 3.23Å; L364-V368 WeakPolarHBondContact O-CG2 3.49Å; L364-V368 PolarHBondContact O-N 3.17Å; I365-V368 PolarHBondContact O-N 2.89Å; V368-Q370 VanDerWaalsContact C-N 3.33Å; V368-Q370 PolarHBondContact O-N 3.07Å; V368-A371 CarbonylContact O-C 3.53Å; V368-A371 PolarHBondContact O-N 2.65Å; V368-A371 VanDerWaalsContact O-N 3.16Å; V368-L372 HydrophobicContact CG1-CD1 3.76Å; V368-L372 HydrophobicContact CG1-CG 4.35Å; V368-L372 WeakPolarHBondContact O-CB 3.32Å; V368-L372 VanDerWaalsContact O-CG 3.31Å; V368-L372 WeakPolarHBondContact O-CG 3.17Å; V368-L372 PolarHBondContact O-N 3.09Å; V368-L387 HydrophobicContact CG2-CD1 3.93Å
369S88.6Confident88Confident57 Ų5762 Ų6240%0.39935%0.349SS..Hα-helixtrans-58.9-44.6175.5179.50000111.4I365 G366 L372 C373I365-S369 WeakPolarHBondContact O-CB 3.46Å; I365-S369 PolarHBondContact O-N 3.4Å; G366-S369 PolarHBondContact O-N 3.27Å; S369-L372 PolarHBondContact O-N 3.12Å; S369-C373 VanDerWaalsContact O-CB 3.27Å; S369-C373 WeakPolarHBondContact O-CB 3.31Å; S369-C373 PolarHBondContact O-N 3.29Å
370Q88.5Confident87.5Confident78 Ų7859.9 Ų59.936%0.36434%0.335SS..Hα-helixtrans-67.9-37175-67-65.7-34.100112.5G366 L367 V368 L372 S374 R379 L383G366-Q370 VanDerWaalsContact O-CG 3.28Å; G366-Q370 WeakPolarHBondContact O-CG 3.44Å; G366-Q370 PolarHBondContact O-N 2.54Å; L367-Q370 PolarHBondContact O-N 3.05Å; V368-Q370 VanDerWaalsContact C-N 3.33Å; V368-Q370 PolarHBondContact O-N 3.07Å; Q370-L372 PolarHBondContact O-N 3.11Å; Q370-S374 WeakPolarHBondContact O-CB 3.36Å; Q370-S374 PolarHBondContact O-N 3.21Å; Q370-R379 VanDerWaalsContact OE1-CZ 3.23Å; Q370-L383 HydrophobicContact CB-CD1 3.79Å
371A86.9Confident86.9Confident3 Ų360.1 Ų60.13%0.02533%0.334CS..Hα-helixtrans-71.1-14.9177.600000113.6L367 V368 R380 L383 T384 L387L367-A371 VanDerWaalsContact O-CB 3.22Å; L367-A371 WeakPolarHBondContact O-CB 3.36Å; L367-A371 PolarHBondContact O-N 3.01Å; V368-A371 CarbonylContact O-C 3.53Å; V368-A371 PolarHBondContact O-N 2.65Å; V368-A371 VanDerWaalsContact O-N 3.16Å; A371-R380 WeakPolarHBondContact O-CG 3.34Å; A371-L383 HydrophobicContact CB-CB 3.75Å; A371-T384 PolarHBondContact O-OG1 2.94Å; A371-L387 HydrophobicContact CB-CD1 3.76Å
372L81.9Confident86.6Confident55 Ų5554.5 Ų54.529%0.28831%0.313SS..Hα-helixtrans-107.4-44.4177.6-65.4176000111.8V244 Y245 V368 S369 Q370 R380V244-L372 HydrophobicContact CB-CD2 3.74Å; V244-L372 HydrophobicContact CG1-CD2 3.63Å; V244-L372 HydrophobicContact CG2-CD2 4.41Å; Y245-L372 WeakPolarHBondContact CB-O 3.34Å; V368-L372 HydrophobicContact CG1-CD1 3.76Å; V368-L372 HydrophobicContact CG1-CG 4.35Å; V368-L372 WeakPolarHBondContact O-CB 3.32Å; V368-L372 VanDerWaalsContact O-CG 3.31Å; V368-L372 WeakPolarHBondContact O-CG 3.17Å; V368-L372 PolarHBondContact O-N 3.09Å; S369-L372 PolarHBondContact O-N 3.12Å; Q370-L372 PolarHBondContact O-N 3.11Å; L372-R380 WeakPolarHBondContact O-CD 3.25Å
373C81.3Confident86.3Confident68 Ų6850.6 Ų50.646%0.45929%0.286SS..Hα-helixtrans-101.7-1.4-167.4-54.50000114.4Y245 S369Y245-C373 HydrophobicContact CD2-CB 4.46Å; S369-C373 VanDerWaalsContact O-CB 3.27Å; S369-C373 WeakPolarHBondContact O-CB 3.31Å; S369-C373 PolarHBondContact O-N 3.29Å
374S82.2Confident86.1Confident5 Ų548 Ų484%0.03527%0.271CS..  trans-68.8134.8-178.6-167.80000111.8Q370 D376 R379 R380Q370-S374 WeakPolarHBondContact O-CB 3.36Å; Q370-S374 PolarHBondContact O-N 3.21Å; S374-D376 VanDerWaalsContact C-N 3.27Å; S374-D376 PolarHBondContact O-N 3.03Å; S374-R379 WeakPolarHBondContact OG-CD 3.27Å; S374-R380 PolarHBondContact O-NH1 3.23Å
375P74.9Confident86Confident130 Ų13046.2 Ų46.284%0.84426%0.261SS*.SBendtrans-68.5-26.8178.727-34.7000112.5S377P375-S377 PolarHBondContact O-N 3.1Å
376D80.9Confident86Confident62 Ų6241.1 Ų41.133%0.33224%0.235SC..  trans-78.2114.9176.8174.12.7000110.3S374 Q378 R379 R380S374-D376 VanDerWaalsContact C-N 3.27Å; S374-D376 PolarHBondContact O-N 3.03Å; D376-Q378 VanDerWaalsContact C-N 3.34Å; D376-Q378 PolarHBondContact O-N 3.49Å; D376-Q378 PolarHBondContact OD1-N 3.24Å; D376-R379 HydrophobicContact CB-CB 3.81Å; D376-R379 PolarHBondContact O-N 2.95Å; D376-R379 PolarHBondContact OD1-N 3.14Å; D376-R379 WeakPolarHBondContact OD2-CB 3.38Å; D376-R380 WeakPolarHBondContact O-CB 3.45Å; D376-R380 PolarHBondContact O-N 3.08Å
377S76.1Confident86.1Confident39 Ų3940.4 Ų40.427%0.27322%0.223SC..Hα-helixtrans-61-39.3-179.9-167.20000112.7P375 R380 R381P375-S377 PolarHBondContact O-N 3.1Å; S377-R380 PolarHBondContact OG-NH2 2.68Å; S377-R381 WeakPolarHBondContact O-CB 3.14Å; S377-R381 PolarHBondContact O-N 3.45Å
378Q78.7Confident86.2Confident25 Ų2539 Ų3912%0.11722%0.217CC..Hα-helixtrans-71.3-40.6-179.7-65.2-173.7-20.200110.9T4 W8 D376 T382T4-Q378 PolarHBondContact O-NE2 3.33Å; T4-Q378 VanDerWaalsContact O-NE2 3.13Å; W8-Q378 HydrophobicContact CH2-CB 3.37Å; W8-Q378 HydrophobicContact CZ2-CB 4.29Å; W8-Q378 HydrophobicContact CZ3-CB 3.94Å; D376-Q378 VanDerWaalsContact C-N 3.34Å; D376-Q378 PolarHBondContact O-N 3.49Å; D376-Q378 PolarHBondContact OD1-N 3.24Å; Q378-T382 WeakPolarHBondContact O-CB 3.16Å; Q378-T382 PolarHBondContact O-N 3.48Å; Q378-T382 PolarHBondContact O-OG1 3.06Å
379R83.5Confident86.4Confident87 Ų8736.2 Ų36.233%0.32820%0.199SC..Hα-helixtrans-60.7-50.3173.8169.3165.9-174.5-173.93.9111.2Q370 S374 D376 R381 T382 L383 Y426Q370-R379 VanDerWaalsContact OE1-CZ 3.23Å; S374-R379 WeakPolarHBondContact OG-CD 3.27Å; D376-R379 HydrophobicContact CB-CB 3.81Å; D376-R379 PolarHBondContact O-N 2.95Å; D376-R379 PolarHBondContact OD1-N 3.14Å; D376-R379 WeakPolarHBondContact OD2-CB 3.38Å; R379-R381 VanDerWaalsContact C-N 3.34Å; R379-R381 PolarHBondContact O-N 3.49Å; R379-T382 PolarHBondContact O-N 3.05Å; R379-L383 HydrophobicContact CG-CD1 3.83Å; R379-L383 HydrophobicContact CG-CG 4.44Å; R379-L383 WeakPolarHBondContact O-CB 3.12Å; R379-L383 VanDerWaalsContact O-CG 3.3Å; R379-L383 WeakPolarHBondContact O-CG 3.21Å; R379-L383 PolarHBondContact O-N 3.25Å; R379-Y426 WeakPolarHBondContact CD-OH 3.31Å; R379-Y426 WeakPolarHBondContact CG-OH 3.5Å; R379-Y426 PolarHBondContact NE-OH 2.91Å
380R84.5Confident86.8Confident45 Ų4535 Ų3517%0.1719%0.188CC..Hα-helixtrans-53.3-55.3178.5-168.4174.552.6-108.22.3109.6A371 L372 S374 D376 S377 T382 L383 T384A371-R380 WeakPolarHBondContact O-CG 3.34Å; L372-R380 WeakPolarHBondContact O-CD 3.25Å; S374-R380 PolarHBondContact O-NH1 3.23Å; D376-R380 WeakPolarHBondContact O-CB 3.45Å; D376-R380 PolarHBondContact O-N 3.08Å; S377-R380 PolarHBondContact OG-NH2 2.68Å; R380-T382 PolarHBondContact O-N 3.31Å; R380-L383 PolarHBondContact O-N 3.24Å; R380-T384 PolarHBondContact O-N 3.46Å; R380-T384 PolarHBondContact O-OG1 3.18Å
381R84.3Confident87.2Confident31 Ų3134.4 Ų34.412%0.11719%0.19CC..Hα-helixtrans-55.1-51.6179.3179179.3168.7-174-4.7113.8I128 L129 I130 G131 L238 S377 R379 L383 T384 F385I128-R381 PolarHBondContact O-NH2 2.78Å; L129-R381 VanDerWaalsContact O-CZ 3.3Å; L129-R381 PolarHBondContact O-NE 3.4Å; L129-R381 PolarHBondContact O-NH2 3.19Å; I130-R381 PolarHBondContact O-NE 3.25Å; I130-R381 PolarHBondContact O-NH1 3.32Å; I130-R381 PolarHBondContact O-NH2 3.34Å; G131-R381 VanDerWaalsContact C-NH1 3.32Å; G131-R381 VanDerWaalsContact C-NH2 3.35Å; G131-R381 PolarHBondContact O-NH1 2.98Å; L238-R381 VanDerWaalsContact CD1-NE 3.27Å; S377-R381 WeakPolarHBondContact O-CB 3.14Å; S377-R381 PolarHBondContact O-N 3.45Å; R379-R381 VanDerWaalsContact C-N 3.34Å; R379-R381 PolarHBondContact O-N 3.49Å; R381-L383 VanDerWaalsContact C-N 3.34Å; R381-L383 PolarHBondContact O-N 3.31Å; R381-T384 PolarHBondContact O-N 3.32Å; R381-F385 HydrophobicContact CG-CD2 3.8Å; R381-F385 HydrophobicContact CG-CE2 3.85Å; R381-F385 WeakPolarHBondContact O-CD2 3.48Å; R381-F385 PolarHBondContact O-N 3.45Å
382T87.8Confident87.6Confident1 Ų135.8 Ų35.81%0.00620%0.198CC..Hα-helixtrans-62.7-42.8-177.7-55.20000111I130 Q378 R379 R380 G386 L422 Y426I130-T382 HydrophobicContact CG1-CG2 4.39Å; Q378-T382 WeakPolarHBondContact O-CB 3.16Å; Q378-T382 PolarHBondContact O-N 3.48Å; Q378-T382 PolarHBondContact O-OG1 3.06Å; R379-T382 PolarHBondContact O-N 3.05Å; R380-T382 PolarHBondContact O-N 3.31Å; T382-G386 PolarHBondContact O-N 3.23Å; T382-L422 HydrophobicContact CG2-CD1 4.3Å; T382-L422 HydrophobicContact CG2-CG 4.4Å; T382-Y426 HydrophobicContact CG2-CD2 3.85Å; T382-Y426 HydrophobicContact CG2-CG 4.01Å
383L90.9Very high88.2Confident5 Ų533.2 Ų33.23%0.02618%0.184CC..Hα-helixtrans-67.3-42.5177.4-67.7177.2000112Q370 A371 R379 R380 R381 G386 L387 L423 Y426Q370-L383 HydrophobicContact CB-CD1 3.79Å; A371-L383 HydrophobicContact CB-CB 3.75Å; R379-L383 HydrophobicContact CG-CD1 3.83Å; R379-L383 HydrophobicContact CG-CG 4.44Å; R379-L383 WeakPolarHBondContact O-CB 3.12Å; R379-L383 VanDerWaalsContact O-CG 3.3Å; R379-L383 WeakPolarHBondContact O-CG 3.21Å; R379-L383 PolarHBondContact O-N 3.25Å; R380-L383 PolarHBondContact O-N 3.24Å; R381-L383 VanDerWaalsContact C-N 3.34Å; R381-L383 PolarHBondContact O-N 3.31Å; L383-G386 PolarHBondContact O-N 3.48Å; L383-L387 WeakPolarHBondContact O-CB 3.38Å; L383-L387 WeakPolarHBondContact O-CG 3.23Å; L383-L387 PolarHBondContact O-N 3.36Å; L383-L423 HydrophobicContact CD2-CD2 3.67Å; L383-Y426 HydrophobicContact CD2-CD1 3.8Å; L383-Y426 HydrophobicContact CD2-CE1 3.8Å; L383-Y426 HydrophobicContact CG-CE1 4.19Å
384T91.1Very high88.8Confident22 Ų2231.5 Ų31.514%0.13517%0.169CC..Hα-helixtrans-62.3-47.6178.3-45.10000111.2L237 A371 R380 R381 L387 V388L237-T384 HydrophobicContact CD1-CG2 3.39Å; L237-T384 HydrophobicContact CD2-CG2 4.44Å; A371-T384 PolarHBondContact O-OG1 2.94Å; R380-T384 PolarHBondContact O-N 3.46Å; R380-T384 PolarHBondContact O-OG1 3.18Å; R381-T384 PolarHBondContact O-N 3.32Å; T384-L387 PolarHBondContact O-N 2.8Å; T384-V388 VanDerWaalsContact O-CG2 3.31Å; T384-V388 WeakPolarHBondContact O-CG2 3.37Å; T384-V388 PolarHBondContact O-N 3.1Å
385F91.8Very high89.3Confident1 Ų134 Ų340%0.00418%0.182CC..Hα-helixtrans-69.6-34.4178.9-76.4-57.5000113.2L129 F234 L237 L238 R381 L387 V388 L389L129-F385 HydrophobicContact CB-CB 4.27Å; L129-F385 HydrophobicContact CB-CD2 4.46Å; L129-F385 HydrophobicContact CB-CG 4.39Å; L129-F385 HydrophobicContact CD2-CB 4.23Å; L129-F385 HydrophobicContact CD2-CD1 3.67Å; L129-F385 HydrophobicContact CD2-CD2 4.22Å; L129-F385 HydrophobicContact CD2-CE1 4.04Å; L129-F385 HydrophobicContact CD2-CG 3.79Å; L129-F385 HydrophobicContact CD2-CZ 4.46Å; F234-F385 HydrophobicContact CB-CE1 4.07Å; F234-F385 HydrophobicContact CB-CZ 4.4Å; F234-F385 HydrophobicContact CD2-CE1 4.27Å; F234-F385 HydrophobicContact CD2-CZ 4.06Å; L237-F385 HydrophobicContact CB-CZ 3.96Å; L237-F385 HydrophobicContact CD1-CE1 4.2Å; L237-F385 HydrophobicContact CD1-CZ 4.31Å; L238-F385 HydrophobicContact CB-CZ 4.25Å; L238-F385 HydrophobicContact CD1-CE2 4.35Å; R381-F385 HydrophobicContact CG-CD2 3.8Å; R381-F385 HydrophobicContact CG-CE2 3.85Å; R381-F385 WeakPolarHBondContact O-CD2 3.48Å; R381-F385 PolarHBondContact O-N 3.45Å; F385-L387 VanDerWaalsContact C-N 3.34Å; F385-V388 PolarHBondContact O-N 3.1Å; F385-L389 WeakPolarHBondContact O-CB 3.3Å; F385-L389 PolarHBondContact O-N 3.04Å
386G94.4Very high90Very high0 Ų029 Ų290%015%0.149CC..Hα-helixtrans-58.4-45.1169.800000112.1T382 L383 L390 G419T382-G386 PolarHBondContact O-N 3.23Å; L383-G386 PolarHBondContact O-N 3.48Å; G386-L390 VanDerWaalsContact O-CB 3.25Å; G386-L390 WeakPolarHBondContact O-CB 3.5Å; G386-L390 PolarHBondContact O-N 3.39Å; G386-G419 VanDerWaalsContact O-CA 3.24Å; G386-G419 WeakPolarHBondContact O-CA 3.11Å
387L95.5Very high90.4Very high19 Ų1926.6 Ų26.610%0.09914%0.138CC..Hα-helixtrans-68.4-40176.2-71.9170.7000112.9L364 L367 V368 A371 L383 T384 F385 L390 V391 L423L364-L387 HydrophobicContact CD2-CD2 4.48Å; L367-L387 HydrophobicContact CB-CD1 4.3Å; L367-L387 HydrophobicContact CB-CD2 4.23Å; L367-L387 HydrophobicContact CD1-CD2 4.39Å; V368-L387 HydrophobicContact CG2-CD1 3.93Å; A371-L387 HydrophobicContact CB-CD1 3.76Å; L383-L387 WeakPolarHBondContact O-CB 3.38Å; L383-L387 WeakPolarHBondContact O-CG 3.23Å; L383-L387 PolarHBondContact O-N 3.36Å; T384-L387 PolarHBondContact O-N 2.8Å; F385-L387 VanDerWaalsContact C-N 3.34Å; L387-L390 PolarHBondContact O-N 3.32Å; L387-V391 WeakPolarHBondContact O-CB 3.45Å; L387-V391 WeakPolarHBondContact O-CG2 3.5Å; L387-V391 PolarHBondContact O-N 2.75Å; L387-L423 HydrophobicContact CD2-CD1 4.38Å
388V95.3Very high91Very high22 Ų2225 Ų2513%0.13313%0.127CC..Hα-helixtrans-60.6-49.2175.9165.20000110.5V230 A233 T384 F385 L390 V392 P393V230-V388 HydrophobicContact CB-CG1 4.39Å; V230-V388 HydrophobicContact CG1-CG1 4.37Å; V230-V388 HydrophobicContact CG2-CG1 4.02Å; A233-V388 HydrophobicContact CB-CG1 3.88Å; A233-V388 HydrophobicContact CB-CG2 3.91Å; T384-V388 VanDerWaalsContact O-CG2 3.31Å; T384-V388 WeakPolarHBondContact O-CG2 3.37Å; T384-V388 PolarHBondContact O-N 3.1Å; F385-V388 PolarHBondContact O-N 3.1Å; V388-L390 VanDerWaalsContact C-N 3.26Å; V388-L390 PolarHBondContact O-N 3.01Å; V388-V392 HydrophobicContact CG1-CG2 4.07Å; V388-V392 VanDerWaalsContact O-CB 3.24Å; V388-V392 WeakPolarHBondContact O-CB 3.13Å; V388-V392 WeakPolarHBondContact O-CG2 3.43Å; V388-V392 PolarHBondContact O-N 2.88Å; V388-P393 WeakPolarHBondContact O-CD 3.32Å
389L96.2Very high91.4Very high5 Ų524.4 Ų24.43%0.02612%0.124CC..Hα-helixtrans-66.9-26.6177.1-76.1-177.5000113.1F126 L129 V230 F385 P393 S416F126-L389 HydrophobicContact CE1-CD1 4.2Å; L129-L389 HydrophobicContact CD1-CD1 3.43Å; L129-L389 VanDerWaalsContact CD1-CD1 3.43Å; L129-L389 HydrophobicContact CD1-CG 4.19Å; V230-L389 HydrophobicContact CG1-CD2 3.95Å; V230-L389 HydrophobicContact CG2-CD2 4.16Å; F385-L389 WeakPolarHBondContact O-CB 3.3Å; F385-L389 PolarHBondContact O-N 3.04Å; L389-P393 WeakPolarHBondContact O-CD 3.41Å; L389-P393 WeakPolarHBondContact O-CG 3.31Å; L389-S416 WeakPolarHBondContact O-CA 3.36Å
390L96.4Very high91.6Very high32 Ų3225.4 Ų25.417%0.16814%0.135CC..Hα-helixtrans-75.5-49.9176.5-178.864.6000111.4L328 G386 L387 V388 S416 L423L328-L390 HydrophobicContact CD1-CD1 3.74Å; G386-L390 VanDerWaalsContact O-CB 3.25Å; G386-L390 WeakPolarHBondContact O-CB 3.5Å; G386-L390 PolarHBondContact O-N 3.39Å; L387-L390 PolarHBondContact O-N 3.32Å; V388-L390 VanDerWaalsContact C-N 3.26Å; V388-L390 PolarHBondContact O-N 3.01Å; L390-S416 WeakPolarHBondContact CD1-O 3.2Å; L390-S416 VanDerWaalsContact O-CB 3.28Å; L390-S416 WeakPolarHBondContact O-CB 3.46Å; L390-S416 PolarHBondContact O-OG 3.3Å; L390-L423 HydrophobicContact CD2-CD1 4.21Å
391V95.5Very high91.5Very high66 Ų6630.2 Ų30.240%0.416%0.158SC..Hα-helixtrans-87.2-46.7-168.9177.20000112.3L387 F394 L395L387-V391 WeakPolarHBondContact O-CB 3.45Å; L387-V391 WeakPolarHBondContact O-CG2 3.5Å; L387-V391 PolarHBondContact O-N 2.75Å; V391-F394 WeakPolarHBondContact O-CA 3.36Å; V391-F394 WeakPolarHBondContact O-CB 3.37Å; V391-F394 PolarHBondContact O-N 3.15Å; V391-L395 HydrophobicContact CG1-CD2 4.33Å; V391-L395 HydrophobicContact CG1-CG 4.48Å; V391-L395 WeakPolarHBondContact O-CG 3.33Å; V391-L395 PolarHBondContact O-N 2.91Å; V391-L395 VanDerWaalsContact O-N 3.15Å
392V95.7Very high91.4Very high31 Ų3134 Ų3419%0.18818%0.175CC..G310 helixtrans-62.8-45.5-170.7176.50000112.3T226 V230 V388 F394 L395T226-V392 WeakPolarHBondContact CG2-O 3.3Å; V230-V392 HydrophobicContact CG2-CB 4.39Å; V230-V392 HydrophobicContact CG2-CG1 4.25Å; V388-V392 HydrophobicContact CG1-CG2 4.07Å; V388-V392 VanDerWaalsContact O-CB 3.24Å; V388-V392 WeakPolarHBondContact O-CB 3.13Å; V388-V392 WeakPolarHBondContact O-CG2 3.43Å; V388-V392 PolarHBondContact O-N 2.88Å; V392-F394 PolarHBondContact O-N 3.44Å; V392-L395 WeakPolarHBondContact O-CB 3.44Å; V392-L395 PolarHBondContact O-N 2.78Å
393P95.3Very high91.2Very high2 Ų239.7 Ų39.71%0.01320%0.197CC..G310 helixtrans-68-16.9172.8-20.835.3000114.4F181 Q223 V388 L389 L415F181-P393 HydrophobicContact CZ-CG 4.44Å; Q223-P393 VanDerWaalsContact CD-O 3.24Å; Q223-P393 PolarHBondContact NE2-O 3.05Å; Q223-P393 PolarHBondContact OE1-O 3.45Å; V388-P393 WeakPolarHBondContact O-CD 3.32Å; L389-P393 WeakPolarHBondContact O-CD 3.41Å; L389-P393 WeakPolarHBondContact O-CG 3.31Å; P393-L415 HydrophobicContact CB-CB 3.68Å; P393-L415 HydrophobicContact CB-CD1 4.44Å; P393-L415 HydrophobicContact CG-CB 4.24Å
394F94.1Very high90.8Very high32 Ų3240.4 Ų40.414%0.1420%0.201CC..G310 helixtrans-84.4-22.3177.4-171.8-114.3000112.6Y321 N324 V391 V392 A397 C398 V412 L413 S416Y321-F394 AromaticContact CD1-CE1 3.76Å; Y321-F394 HydrophobicContact CD1-CE1 3.76Å; Y321-F394 HydrophobicContact CD1-CZ 4.18Å; Y321-F394 HydrophobicContact CE1-CE1 4.25Å; Y321-F394 HydrophobicContact CG-CE1 4.42Å; N324-F394 HydrophobicContact CB-CE2 4.24Å; N324-F394 HydrophobicContact CB-CZ 4.11Å; V391-F394 WeakPolarHBondContact O-CA 3.36Å; V391-F394 WeakPolarHBondContact O-CB 3.37Å; V391-F394 PolarHBondContact O-N 3.15Å; V392-F394 PolarHBondContact O-N 3.44Å; F394-A397 HydrophobicContact CE2-CB 4.46Å; F394-A397 PolarHBondContact O-N 3.24Å; F394-C398 HydrophobicContact CD1-CB 4.09Å; F394-C398 HydrophobicContact CE1-CB 3.93Å; F394-C398 PolarHBondContact O-N 2.74Å; F394-V412 HydrophobicContact CD2-CG1 3.91Å; F394-V412 HydrophobicContact CE2-CG1 3.84Å; F394-L413 HydrophobicContact CD2-CD2 3.97Å; F394-L413 HydrophobicContact CE2-CD2 3.92Å; F394-S416 WeakPolarHBondContact CB-OG 3.34Å; F394-S416 PolarHBondContact N-OG 2.88Å
395L92.4Very high90.2Very high57 Ų5739.6 Ų39.630%0.29820%0.197SC..G310 helixtrans-53.7-41.2-173.3-74.5176.3000114.9V391 V392 A397 C398 F401V391-L395 HydrophobicContact CG1-CD2 4.33Å; V391-L395 HydrophobicContact CG1-CG 4.48Å; V391-L395 WeakPolarHBondContact O-CG 3.33Å; V391-L395 PolarHBondContact O-N 2.91Å; V391-L395 VanDerWaalsContact O-N 3.15Å; V392-L395 WeakPolarHBondContact O-CB 3.44Å; V392-L395 PolarHBondContact O-N 2.78Å; L395-A397 PolarHBondContact O-N 2.8Å; L395-A397 VanDerWaalsContact O-N 3.15Å; L395-C398 PolarHBondContact O-N 3.14Å; L395-C398 PolarHBondContact O-SG 2.92Å; L395-F401 HydrophobicContact CB-CE2 4.28Å
396P89.6Confident89.4Confident25 Ų2544.4 Ų44.416%0.16222%0.218CC..G310 helixtrans-66.4-16.3178.3-25.538.7000114.1T226 F402T226-P396 HydrophobicContact CG2-CG 3.61Å; P396-F402 HydrophobicContact CB-CZ 4.34Å; P396-F402 WeakPolarHBondContact O-CE2 3.28Å; P396-F402 VanDerWaalsContact O-CZ 3.32Å; P396-F402 WeakPolarHBondContact O-CZ 3.27Å
397A88.5Confident88.4Confident12 Ų1244.9 Ų44.910%0.09922%0.221CC..G310 helixtrans-102.1-5.8179.100000113.9F394 L395 N399 V412F394-A397 HydrophobicContact CE2-CB 4.46Å; F394-A397 PolarHBondContact O-N 3.24Å; L395-A397 PolarHBondContact O-N 2.8Å; L395-A397 VanDerWaalsContact O-N 3.15Å; A397-N399 VanDerWaalsContact C-N 3.26Å; A397-N399 PolarHBondContact O-N 2.68Å; A397-N399 PolarHBondContact O-ND2 3.03Å; A397-V412 HydrophobicContact CB-CB 4.42Å; A397-V412 HydrophobicContact CB-CG1 3.26Å; A397-V412 HydrophobicContact CB-CG2 4.27Å
398C88.9Confident87.9Confident5 Ų544.2 Ų44.23%0.03422%0.218CC..SBendtrans-81.57.6-172.670.20000114.6Y321 F394 L395 I400Y321-C398 HydrophobicContact CE1-CB 3.69Å; Y321-C398 WeakPolarHBondContact CE1-O 3.26Å; Y321-C398 PolarHBondContact OH-O 2.97Å; F394-C398 HydrophobicContact CD1-CB 4.09Å; F394-C398 HydrophobicContact CE1-CB 3.93Å; F394-C398 PolarHBondContact O-N 2.74Å; L395-C398 PolarHBondContact O-N 3.14Å; L395-C398 PolarHBondContact O-SG 2.92Å; C398-I400 HydrophobicContact CB-CD1 4.4Å; C398-I400 HydrophobicContact CB-CG1 4.34Å; C398-I400 PolarHBondContact O-N 3.31Å; C398-I400 VanDerWaalsContact SG-CB 3.59Å; C398-I400 WeakPolarHBondContact SG-CD1 3.36Å; C398-I400 WeakPolarHBondContact SG-CG1 3.35Å
399N88.3Confident87.3Confident12 Ų1243.6 Ų43.66%0.06422%0.215CC..SBendtrans59.810.8-178.7-67.6-87.3000115.8N302 Y317 A397 F402 V404N302-N399 PolarHBondContact ND2-OD1 3.02Å; Y317-N399 HydrophobicContact CD1-CB 4.27Å; Y317-N399 HydrophobicContact CD2-CB 3.93Å; Y317-N399 HydrophobicContact CE1-CB 3.99Å; Y317-N399 HydrophobicContact CE2-CB 3.62Å; Y317-N399 HydrophobicContact CG-CB 4.24Å; A397-N399 VanDerWaalsContact C-N 3.26Å; A397-N399 PolarHBondContact O-N 2.68Å; A397-N399 PolarHBondContact O-ND2 3.03Å; N399-F402 WeakPolarHBondContact CA-O 3.27Å; N399-V404 PolarHBondContact OD1-N 3.26Å; N399-V404 PolarHBondContact OD1-O 3.38Å
400I86.8Confident86.8Confident109 Ų10943.3 Ų43.356%0.55921%0.213SC*.SBendtrans-75.5-45.3179.1-67.7177.2000111.3C398C398-I400 HydrophobicContact CB-CD1 4.4Å; C398-I400 HydrophobicContact CB-CG1 4.34Å; C398-I400 PolarHBondContact O-N 3.31Å; C398-I400 VanDerWaalsContact SG-CB 3.59Å; C398-I400 WeakPolarHBondContact SG-CD1 3.36Å; C398-I400 WeakPolarHBondContact SG-CG1 3.35Å
401F82.6Confident86.5Confident146 Ų14643.3 Ų43.364%0.6421%0.211SC*.SBendtrans-88.5-35.7-174.9-61.9-67.6000113.3L395L395-F401 HydrophobicContact CB-CE2 4.28Å
402F81.8Confident86.1Confident111 Ų11141.4 Ų41.449%0.48720%0.2SC..SBendtrans-154.1157.6-178.145.4-93.6000109.6P396 N399 V404P396-F402 HydrophobicContact CB-CZ 4.34Å; P396-F402 WeakPolarHBondContact O-CE2 3.28Å; P396-F402 VanDerWaalsContact O-CZ 3.32Å; P396-F402 WeakPolarHBondContact O-CZ 3.27Å; N399-F402 WeakPolarHBondContact CA-O 3.27Å; F402-V404 HydrophobicContact CD2-CG2 3.66Å; F402-V404 HydrophobicContact CE2-CG2 3.62Å
403R83.6Confident86.1Confident120 Ų12040.1 Ų40.145%0.45319%0.191SC..  trans-68.2132.7175-64.5178.7179.7175.4-1.7109.7F297 S305F297-R403 WeakPolarHBondContact CE2-O 3.33Å; S305-R403 PolarHBondContact O-NE 3.48Å
404V83.6Confident86.2Confident19 Ų1940 Ų4012%0.11519%0.191CC..  trans-123.4130.5178.9-174.60000108.2N302 N399 F402N302-V404 PolarHBondContact ND2-O 3.18Å; N399-V404 PolarHBondContact OD1-N 3.26Å; N399-V404 PolarHBondContact OD1-O 3.38Å; F402-V404 HydrophobicContact CD2-CG2 3.66Å; F402-V404 HydrophobicContact CE2-CG2 3.62Å
405G77.3Confident86.3Confident5 Ų539.4 Ų39.45%0.05219%0.189CC..SBendtrans-72-27-179.700000114.9D301 V407D301-G405 CarbonylContact C-O 3.55Å; D301-G405 VanDerWaalsContact C-O 3.31Å; G405-V407 PolarHBondContact O-N 2.93Å
406F75Confident86.5Confident102 Ų10236.7 Ų36.745%0.44718%0.175SC..  trans-87.198.5-178.6-52.3-71.2000110.9A409F406-A409 HydrophobicContact CB-CB 4.49Å
407V73.7Confident86.8Confident10 Ų1035.5 Ų35.56%0.06117%0.167CC..SBendtrans-66.9-46.4-176.81760000112.9D301 N302 Y320 N324 G405D301-V407 WeakPolarHBondContact O-CG2 3.34Å; N302-V407 HydrophobicContact CB-CG2 3.57Å; N302-V407 VanDerWaalsContact CG-CG2 3.49Å; Y320-V407 HydrophobicContact CD1-CG1 3.32Å; Y320-V407 HydrophobicContact CD2-CG1 3.48Å; Y320-V407 VanDerWaalsContact CD2-CG1 3.48Å; Y320-V407 HydrophobicContact CE1-CG1 3.26Å; Y320-V407 HydrophobicContact CE2-CB 4.31Å; Y320-V407 HydrophobicContact CE2-CG1 3.39Å; Y320-V407 HydrophobicContact CE2-CG2 4.05Å; Y320-V407 HydrophobicContact CG-CG1 3.42Å; Y320-V407 VanDerWaalsContact CG-CG1 3.42Å; N324-V407 PolarHBondContact ND2-O 3.48Å; G405-V407 PolarHBondContact O-N 2.93Å
408V84.9Confident87.3Confident6 Ų635 Ų354%0.03616%0.163CC..SBendtrans-139133.4174.5179.50000106.7L323 L327 W338L323-V408 HydrophobicContact CB-CG2 4.03Å; L323-V408 HydrophobicContact CD1-CG2 4.19Å; L327-V408 HydrophobicContact CD1-CG1 3.34Å; L327-V408 HydrophobicContact CG-CG1 4.38Å; W338-V408 HydrophobicContact CB-CB 4.16Å; W338-V408 HydrophobicContact CD2-CB 3.91Å; W338-V408 HydrophobicContact CD2-CG1 4.03Å; W338-V408 HydrophobicContact CE3-CB 4.43Å; W338-V408 HydrophobicContact CG-CB 3.78Å; W338-V408 HydrophobicContact CG-CG1 4.21Å; W338-V408 HydrophobicContact CZ2-CG1 4.23Å
409A82.3Confident87.7Confident8 Ų834.8 Ų34.87%0.06616%0.161CC..  trans-156.5138.2176.100000110.7F406 R411 V412F406-A409 HydrophobicContact CB-CB 4.49Å; A409-R411 VanDerWaalsContact C-N 3.31Å; A409-R411 HydrophobicContact CB-CG 4.04Å; A409-R411 PolarHBondContact O-N 3.26Å; A409-V412 HydrophobicContact CB-CB 4.46Å; A409-V412 HydrophobicContact CB-CG2 3.97Å; A409-V412 PolarHBondContact O-N 3.23Å
410E87.6Confident88.1Confident0 Ų035.6 Ų35.60%016%0.164CC..G310 helixtrans-61.7-44.9180-51.8177.6-147.200109.7V161 E164 L334 C335 V412 L413 R460V161-E410 HydrophobicContact CG2-CB 4.04Å; V161-E410 WeakPolarHBondContact O-CB 3.35Å; E164-E410 HydrophobicContact CB-CB 3.84Å; E164-E410 HydrophobicContact CB-CG 4.46Å; E164-E410 WeakPolarHBondContact OE2-CB 2.99Å; E164-E410 PolarHBondContact OE2-N 3.25Å; L334-E410 WeakPolarHBondContact CB-OE1 3.47Å; L334-E410 HydrophobicContact CD2-CG 3.86Å; C335-E410 PolarHBondContact N-OE1 3.41Å; E410-V412 PolarHBondContact O-N 3.31Å; E410-V412 VanDerWaalsContact O-N 3.08Å; E410-L413 PolarHBondContact O-N 2.89Å; E410-R460 IonicContact OE1-CZ 2.9Å; E410-R460 IonicContact OE1-NE 3.76Å; E410-R460 PolarHBondContact OE1-NE 2.93Å; E410-R460 IonicContact OE1-NH2 3.26Å; E410-R460 PolarHBondContact OE1-NH2 3.23Å
411R88.5Confident88.6Confident32 Ų3230.4 Ų30.412%0.12114%0.137CC..G310 helixtrans-57.9-23.9178.464.6177.1178.5-151.75.1115.5D45 E164 A409 L413D45-R411 IonicContact OD2-NH1 3.97Å; D45-R411 PolarHBondContact OD2-NH1 3.48Å; E164-R411 HydrophobicContact CG-CB 4.27Å; E164-R411 VanDerWaalsContact OE1-CD 3.23Å; E164-R411 WeakPolarHBondContact OE1-CD 3.22Å; E164-R411 WeakPolarHBondContact OE1-CG 3.45Å; E164-R411 IonicContact OE1-CZ 3.95Å; E164-R411 IonicContact OE1-NE 2.68Å; E164-R411 IonicContact OE1-NH1 2.79Å; E164-R411 PolarHBondContact OE2-N 2.85Å; A409-R411 VanDerWaalsContact C-N 3.31Å; A409-R411 HydrophobicContact CB-CG 4.04Å; A409-R411 PolarHBondContact O-N 3.26Å; R411-L413 VanDerWaalsContact C-N 3.31Å
412V88.2Confident89.2Confident26 Ų2623.4 Ų23.416%0.15811%0.107CC..G310 helixtrans-74.4-27.5177.8168.10000111.2F394 A397 A409 E410F394-V412 HydrophobicContact CD2-CG1 3.91Å; F394-V412 HydrophobicContact CE2-CG1 3.84Å; A397-V412 HydrophobicContact CB-CB 4.42Å; A397-V412 HydrophobicContact CB-CG1 3.26Å; A397-V412 HydrophobicContact CB-CG2 4.27Å; A409-V412 HydrophobicContact CB-CB 4.46Å; A409-V412 HydrophobicContact CB-CG2 3.97Å; A409-V412 PolarHBondContact O-N 3.23Å; E410-V412 PolarHBondContact O-N 3.31Å; E410-V412 VanDerWaalsContact O-N 3.08Å
413L95.1Very high89.8Confident3 Ų318.9 Ų18.92%0.0169%0.087CC..SBendtrans-91.5-2.7-173.1-61.9174.9000113.5V161 N324 L327 L328 F394 E410 R411 L415 S416 S417V161-L413 HydrophobicContact CG1-CB 4.42Å; V161-L413 HydrophobicContact CG2-CB 3.82Å; V161-L413 HydrophobicContact CG2-CD1 3.86Å; V161-L413 HydrophobicContact CG2-CG 4.43Å; N324-L413 HydrophobicContact CB-CD1 4.29Å; N324-L413 HydrophobicContact CB-CD2 4.06Å; L327-L413 HydrophobicContact CB-CD1 3.94Å; L327-L413 HydrophobicContact CD1-CD1 4.24Å; L328-L413 HydrophobicContact CD2-CB 4.26Å; L328-L413 HydrophobicContact CD2-CD1 4.49Å; L328-L413 HydrophobicContact CG-CD1 4.34Å; F394-L413 HydrophobicContact CD2-CD2 3.97Å; F394-L413 HydrophobicContact CE2-CD2 3.92Å; E410-L413 PolarHBondContact O-N 2.89Å; R411-L413 VanDerWaalsContact C-N 3.31Å; L413-L415 PolarHBondContact O-N 3.47Å; L413-S416 PolarHBondContact O-N 3.32Å; L413-S417 VanDerWaalsContact O-CB 3.27Å; L413-S417 WeakPolarHBondContact O-CB 3.27Å; L413-S417 PolarHBondContact O-N 2.98Å; L413-S417 PolarHBondContact O-OG 3.35Å
414Y96.9Very high90.4Very high1 Ų114.5 Ų14.50%0.0047%0.073CC..THydrogen-bonded Turntrans-53.9-55.1-175.6-170.9-88000112.5H115 I118 F156 H162 L175 A178 S417H115-Y414 AromaticContact ND1-CE2 3.78Å; H115-Y414 AromaticContact ND1-CZ 3.7Å; H115-Y414 PolarHBondContact ND1-OH 3.25Å; I118-Y414 HydrophobicContact CG2-CE1 4.17Å; F156-Y414 WeakPolarHBondContact CE2-O 3.32Å; F156-Y414 HydrophobicContact CZ-CD1 4.47Å; F156-Y414 AromaticContact CZ-CE1 3.93Å; F156-Y414 HydrophobicContact CZ-CE1 3.93Å; H162-Y414 HydrophobicContact CB-CD2 3.98Å; H162-Y414 HydrophobicContact CB-CE2 3.85Å; H162-Y414 AromaticContact CD2-CD2 3.42Å; H162-Y414 VanDerWaalsContact CD2-CD2 3.42Å; H162-Y414 WeakPolarHBondContact CD2-CD2 3.36Å; H162-Y414 AromaticContact CD2-CE2 3.79Å; H162-Y414 AromaticContact CG-CD2 3.66Å; H162-Y414 AromaticContact CG-CE2 3.59Å; H162-Y414 AromaticContact ND1-CE2 3.9Å; L175-Y414 HydrophobicContact CD2-CE1 4.27Å; L175-Y414 HydrophobicContact CD2-CE2 3.67Å; L175-Y414 VanDerWaalsContact CD2-OH 3.29Å; L175-Y414 WeakPolarHBondContact CD2-OH 3.35Å; A178-Y414 HydrophobicContact CB-CD1 3.86Å; A178-Y414 HydrophobicContact CB-CE1 3.53Å; Y414-S417 PolarHBondContact O-OG 3.03Å
415L96.1Very high90.8Very high18 Ų1813.6 Ų13.69%0.0947%0.067CC..THydrogen-bonded Turntrans-69.8-44177.1-80.2171.7000112.7A178 F181 P393 L413 S417 A418A178-L415 HydrophobicContact CB-CD2 3.76Å; A178-L415 HydrophobicContact CB-CG 4.25Å; F181-L415 HydrophobicContact CD1-CD2 4.02Å; F181-L415 HydrophobicContact CD2-CD1 3.93Å; F181-L415 HydrophobicContact CD2-CD2 4.5Å; F181-L415 HydrophobicContact CE1-CD2 4.38Å; F181-L415 HydrophobicContact CE2-CD1 4.27Å; F181-L415 HydrophobicContact CG-CD1 4.27Å; F181-L415 HydrophobicContact CG-CD2 4.11Å; P393-L415 HydrophobicContact CB-CB 3.68Å; P393-L415 HydrophobicContact CB-CD1 4.44Å; P393-L415 HydrophobicContact CG-CB 4.24Å; L413-L415 PolarHBondContact O-N 3.47Å; L415-S417 PolarHBondContact O-N 3.31Å; L415-A418 VanDerWaalsContact O-CB 3.25Å; L415-A418 WeakPolarHBondContact O-CB 3.37Å; L415-A418 PolarHBondContact O-N 3Å
416S96.6Very high91.5Very high1 Ų113.9 Ų13.91%0.0077%0.067CC..Hα-helixtrans-61.3-29.6-179.4-70.10000113.7L389 L390 F394 L413 A418 G419 Y420L389-S416 WeakPolarHBondContact O-CA 3.36Å; L390-S416 WeakPolarHBondContact CD1-O 3.2Å; L390-S416 VanDerWaalsContact O-CB 3.28Å; L390-S416 WeakPolarHBondContact O-CB 3.46Å; L390-S416 PolarHBondContact O-OG 3.3Å; F394-S416 WeakPolarHBondContact CB-OG 3.34Å; F394-S416 PolarHBondContact N-OG 2.88Å; L413-S416 PolarHBondContact O-N 3.32Å; S416-A418 PolarHBondContact O-N 3.39Å; S416-G419 PolarHBondContact O-N 2.84Å; S416-G419 VanDerWaalsContact O-N 3.1Å; S416-Y420 PolarHBondContact O-N 3.38Å
417S97.6Very high92.2Very high0 Ų011.7 Ų11.70%06%0.064CC..Hα-helixtrans-61.2-23.9175.473.10000112.8F156 H162 L413 Y414 L415 G419 Y420 C421F156-S417 WeakPolarHBondContact CE2-OG 3.49Å; H162-S417 PolarHBondContact NE2-OG 2.96Å; L413-S417 VanDerWaalsContact O-CB 3.27Å; L413-S417 WeakPolarHBondContact O-CB 3.27Å; L413-S417 PolarHBondContact O-N 2.98Å; L413-S417 PolarHBondContact O-OG 3.35Å; Y414-S417 PolarHBondContact O-OG 3.03Å; L415-S417 PolarHBondContact O-N 3.31Å; S417-G419 VanDerWaalsContact C-N 3.34Å; S417-Y420 PolarHBondContact O-N 2.99Å; S417-C421 WeakPolarHBondContact O-CB 3.44Å; S417-C421 PolarHBondContact O-N 3.44Å; S417-C421 PolarHBondContact O-SG 2.88Å
418A97.5Very high93Very high1 Ų113.3 Ų13.31%0.0087%0.072CC..Hα-helixtrans-63.2-41.8174.300000111.5M122 F126 F156 L415 S416 C421 L422M122-A418 HydrophobicContact CE-CB 3.66Å; M122-A418 HydrophobicContact SD-CB 4.29Å; F126-A418 HydrophobicContact CE1-CB 4.19Å; F126-A418 WeakPolarHBondContact CE1-O 3.45Å; F126-A418 HydrophobicContact CZ-CB 4.01Å; F126-A418 WeakPolarHBondContact CZ-O 3.23Å; F156-A418 HydrophobicContact CD2-CB 3.95Å; F156-A418 HydrophobicContact CE2-CB 3.88Å; L415-A418 VanDerWaalsContact O-CB 3.25Å; L415-A418 WeakPolarHBondContact O-CB 3.37Å; L415-A418 PolarHBondContact O-N 3Å; S416-A418 PolarHBondContact O-N 3.39Å; A418-C421 PolarHBondContact O-N 3.45Å; A418-L422 WeakPolarHBondContact O-CB 3.46Å; A418-L422 PolarHBondContact O-N 2.8Å
419G97Very high93.1Very high0 Ų013 Ų130%07%0.07CC..Hα-helixtrans-63.6-43.6173.800000112.1G386 S416 S417 L422 L423G386-G419 VanDerWaalsContact O-CA 3.24Å; G386-G419 WeakPolarHBondContact O-CA 3.11Å; S416-G419 PolarHBondContact O-N 2.84Å; S416-G419 VanDerWaalsContact O-N 3.1Å; S417-G419 VanDerWaalsContact C-N 3.34Å; G419-L422 PolarHBondContact O-N 3.37Å; G419-L423 VanDerWaalsContact O-CG 3.3Å; G419-L423 WeakPolarHBondContact O-CG 3.41Å; G419-L423 PolarHBondContact O-N 3.37Å
420Y97.1Very high93.3Very high29 Ų2915 Ų1511%0.1148%0.078CC..Hα-helixtrans-59.6-48.5174.1169.1-99.3000112.5H159 L328 L329 S416 S417 L422 L423 L424 Y453H159-Y420 AromaticContact CD2-CE1 3.93Å; H159-Y420 AromaticContact NE2-CD1 3.74Å; H159-Y420 AromaticContact NE2-CE1 3.54Å; L328-Y420 HydrophobicContact CB-CD1 4.35Å; L328-Y420 HydrophobicContact CB-CD2 4.09Å; L328-Y420 HydrophobicContact CB-CE2 4.42Å; L328-Y420 HydrophobicContact CB-CG 4.06Å; L328-Y420 WeakPolarHBondContact O-CE1 3.24Å; L328-Y420 VanDerWaalsContact O-CZ 3.23Å; L328-Y420 PolarHBondContact O-OH 3.28Å; L329-Y420 HydrophobicContact CD2-CE2 3.74Å; L329-Y420 HydrophobicContact CG-CE2 4.33Å; S416-Y420 PolarHBondContact O-N 3.38Å; S417-Y420 PolarHBondContact O-N 2.99Å; Y420-L422 VanDerWaalsContact C-N 3.28Å; Y420-L422 PolarHBondContact O-N 2.82Å; Y420-L423 PolarHBondContact O-N 3.26Å; Y420-L424 HydrophobicContact CE1-CD2 4.02Å; Y420-L424 WeakPolarHBondContact O-CB 3.29Å; Y420-L424 PolarHBondContact O-N 2.86Å; Y420-Y453 PolarHBondContact OH-OH 3.24Å
421C97.4Very high93.3Very high0 Ų017.1 Ų17.10%09%0.093CC..Hα-helixtrans-62.7-36.6-179.2-66.80000111.9F155 F156 S417 A418 A425F155-C421 HydrophobicContact CB-CB 4.1Å; F156-C421 HydrophobicContact CB-CB 4.33Å; F156-C421 PolarHBondContact N-SG 2.95Å; S417-C421 WeakPolarHBondContact O-CB 3.44Å; S417-C421 PolarHBondContact O-N 3.44Å; S417-C421 PolarHBondContact O-SG 2.88Å; A418-C421 PolarHBondContact O-N 3.45Å; C421-A425 WeakPolarHBondContact O-CB 3.37Å; C421-A425 PolarHBondContact O-N 3.37Å
422L95.4Very high93.2Very high0 Ų016 Ų160%09%0.089CC..Hα-helixtrans-64.9-46.9173.7-179.458.9000111.9F126 I130 T382 A418 G419 Y420 L424 A425 Y426F126-L422 HydrophobicContact CD1-CB 4.21Å; F126-L422 HydrophobicContact CD1-CD1 4.19Å; F126-L422 HydrophobicContact CD1-CD2 4.24Å; F126-L422 HydrophobicContact CD1-CG 4.45Å; F126-L422 HydrophobicContact CE1-CB 4.01Å; I130-L422 HydrophobicContact CD1-CD1 3.59Å; I130-L422 HydrophobicContact CG1-CD1 3.75Å; T382-L422 HydrophobicContact CG2-CD1 4.3Å; T382-L422 HydrophobicContact CG2-CG 4.4Å; A418-L422 WeakPolarHBondContact O-CB 3.46Å; A418-L422 PolarHBondContact O-N 2.8Å; G419-L422 PolarHBondContact O-N 3.37Å; Y420-L422 VanDerWaalsContact C-N 3.28Å; Y420-L422 PolarHBondContact O-N 2.82Å; L422-L424 VanDerWaalsContact C-N 3.33Å; L422-L424 PolarHBondContact O-N 3.45Å; L422-A425 PolarHBondContact O-N 3.13Å; L422-Y426 WeakPolarHBondContact O-CB 3.26Å; L422-Y426 PolarHBondContact O-N 3.27Å
423L95.4Very high93Very high15 Ų1518.8 Ų18.88%0.07910%0.098CC..Hα-helixtrans-63.7-38.4177-68.3173000112L383 L387 L390 G419 Y420 S427L383-L423 HydrophobicContact CD2-CD2 3.67Å; L387-L423 HydrophobicContact CD2-CD1 4.38Å; L390-L423 HydrophobicContact CD2-CD1 4.21Å; G419-L423 VanDerWaalsContact O-CG 3.3Å; G419-L423 WeakPolarHBondContact O-CG 3.41Å; G419-L423 PolarHBondContact O-N 3.37Å; Y420-L423 PolarHBondContact O-N 3.26Å; L423-S427 WeakPolarHBondContact O-CB 3.46Å; L423-S427 PolarHBondContact O-N 3.31Å; L423-S427 PolarHBondContact O-OG 3.21Å
424L94.8Very high92.6Very high29 Ų2928.2 Ų28.215%0.15213%0.133CC..Hα-helixtrans-65.1-49.7176.2178.662.3000111.1F155 Y420 L422 Y426 S427 L428F155-L424 HydrophobicContact CD1-CD2 4.02Å; F155-L424 HydrophobicContact CD2-CD2 4.07Å; F155-L424 HydrophobicContact CD2-CG 4.46Å; F155-L424 HydrophobicContact CE1-CD2 4.05Å; F155-L424 HydrophobicContact CE2-CD2 4.08Å; F155-L424 HydrophobicContact CE2-CG 4.3Å; F155-L424 HydrophobicContact CG-CD2 4.03Å; F155-L424 HydrophobicContact CZ-CD2 4.06Å; Y420-L424 HydrophobicContact CE1-CD2 4.02Å; Y420-L424 WeakPolarHBondContact O-CB 3.29Å; Y420-L424 PolarHBondContact O-N 2.86Å; L422-L424 VanDerWaalsContact C-N 3.33Å; L422-L424 PolarHBondContact O-N 3.45Å; L424-Y426 VanDerWaalsContact C-N 3.32Å; L424-Y426 PolarHBondContact O-N 3.4Å; L424-S427 PolarHBondContact O-N 3.08Å; L424-L428 HydrophobicContact CD1-CD1 3.91Å; L424-L428 HydrophobicContact CD1-CG 4.17Å; L424-L428 HydrophobicContact CG-CD1 3.88Å; L424-L428 WeakPolarHBondContact O-CB 3.22Å; L424-L428 VanDerWaalsContact O-CG 3.32Å; L424-L428 WeakPolarHBondContact O-CG 3.29Å; L424-L428 PolarHBondContact O-N 2.88Å
425A92.8Very high92Very high0 Ų034.5 Ų34.50%016%0.157CC..Hα-helixtrans-59.7-43.1178.200000111.8T148 L151 A152 C421 L422 G429T148-A425 HydrophobicContact CG2-CB 4.12Å; L151-A425 HydrophobicContact CB-CB 4.27Å; L151-A425 HydrophobicContact CD2-CB 4.17Å; L151-A425 HydrophobicContact CG-CB 4.11Å; A152-A425 HydrophobicContact CB-CB 3.77Å; C421-A425 WeakPolarHBondContact O-CB 3.37Å; C421-A425 PolarHBondContact O-N 3.37Å; L422-A425 PolarHBondContact O-N 3.13Å; A425-G429 PolarHBondContact O-N 2.92Å
426Y91.1Very high91.3Very high11 Ų1138.2 Ų38.24%0.04318%0.176CC..Hα-helixtrans-60.5-49173.8170.9-97.7000111.9W8 R379 T382 L383 L422 L424 L428 G429 Q430W8-Y426 HydrophobicContact CD2-CE2 4.4Å; W8-Y426 AromaticContact CE2-CE2 3.97Å; W8-Y426 AromaticContact CH2-CE2 3.95Å; W8-Y426 HydrophobicContact CH2-CE2 3.95Å; W8-Y426 AromaticContact CZ2-CD2 3.91Å; W8-Y426 HydrophobicContact CZ2-CD2 3.91Å; W8-Y426 AromaticContact CZ2-CE2 3.74Å; W8-Y426 HydrophobicContact CZ2-CE2 3.74Å; W8-Y426 HydrophobicContact CZ3-CE2 4.42Å; R379-Y426 WeakPolarHBondContact CD-OH 3.31Å; R379-Y426 WeakPolarHBondContact CG-OH 3.5Å; R379-Y426 PolarHBondContact NE-OH 2.91Å; T382-Y426 HydrophobicContact CG2-CD2 3.85Å; T382-Y426 HydrophobicContact CG2-CG 4.01Å; L383-Y426 HydrophobicContact CD2-CD1 3.8Å; L383-Y426 HydrophobicContact CD2-CE1 3.8Å; L383-Y426 HydrophobicContact CG-CE1 4.19Å; L422-Y426 WeakPolarHBondContact O-CB 3.26Å; L422-Y426 PolarHBondContact O-N 3.27Å; L424-Y426 VanDerWaalsContact C-N 3.32Å; L424-Y426 PolarHBondContact O-N 3.4Å; Y426-L428 VanDerWaalsContact C-N 3.33Å; Y426-L428 PolarHBondContact O-N 3.09Å; Y426-G429 PolarHBondContact O-N 3.11Å; Y426-Q430 HydrophobicContact CD1-CG 4.45Å; Y426-Q430 HydrophobicContact CD2-CG 4.39Å; Y426-Q430 HydrophobicContact CE1-CG 3.89Å; Y426-Q430 HydrophobicContact CE2-CG 3.84Å; Y426-Q430 WeakPolarHBondContact O-CG 3.27Å; Y426-Q430 PolarHBondContact O-N 2.94Å; Y426-Q430 PolarHBondContact OH-NE2 3.47Å
427S90.3Very high90.9Very high56 Ų5646.8 Ų46.839%0.39221%0.213SC..Hα-helixtrans-61.4-41.6-178.9-58.80000111.7L423 L424 Q430 C431L423-S427 WeakPolarHBondContact O-CB 3.46Å; L423-S427 PolarHBondContact O-N 3.31Å; L423-S427 PolarHBondContact O-OG 3.21Å; L424-S427 PolarHBondContact O-N 3.08Å; S427-Q430 PolarHBondContact O-N 3.08Å; S427-C431 PolarHBondContact O-N 2.85Å; S427-C431 PolarHBondContact O-SG 3.04Å; S427-C431 VanDerWaalsContact O-SG 3.34Å
428L89.6Confident90.3Very high43 Ų4353 Ų5323%0.22524%0.238CC..Hα-helixtrans-66.5-39.9175.8-71168.4000112.4F155 L424 Y426 Q430 C431 C432 L446F155-L428 HydrophobicContact CE2-CD1 3.57Å; F155-L428 HydrophobicContact CZ-CD1 3.75Å; L424-L428 HydrophobicContact CD1-CD1 3.91Å; L424-L428 HydrophobicContact CD1-CG 4.17Å; L424-L428 HydrophobicContact CG-CD1 3.88Å; L424-L428 WeakPolarHBondContact O-CB 3.22Å; L424-L428 VanDerWaalsContact O-CG 3.32Å; L424-L428 WeakPolarHBondContact O-CG 3.29Å; L424-L428 PolarHBondContact O-N 2.88Å; Y426-L428 VanDerWaalsContact C-N 3.33Å; Y426-L428 PolarHBondContact O-N 3.09Å; L428-Q430 VanDerWaalsContact C-N 3.33Å; L428-Q430 PolarHBondContact O-N 3.48Å; L428-C431 PolarHBondContact O-N 3.45Å; L428-C432 WeakPolarHBondContact O-CB 3.45Å; L428-C432 PolarHBondContact O-N 2.97Å; L428-C432 PolarHBondContact O-SG 2.95Å; L428-L446 HydrophobicContact CD1-CD1 3.77Å
429G87.6Confident89.6Confident0 Ų056.9 Ų56.90%025%0.254CS..Hα-helixtrans-58.7-45.1172.800000111.8A425 Y426 C432 Y433A425-G429 PolarHBondContact O-N 2.92Å; Y426-G429 PolarHBondContact O-N 3.11Å; G429-C432 PolarHBondContact O-N 3.46Å; G429-Y433 WeakPolarHBondContact O-CB 3.47Å; G429-Y433 PolarHBondContact O-N 3.3Å
430Q86.4Confident89.1Confident49 Ų4965.7 Ų65.723%0.22929%0.292CS..Hα-helixtrans-66.1-39.9176.1-69.7-62.4-21.900113.1Y426 S427 L428 Y433 R434Y426-Q430 HydrophobicContact CD1-CG 4.45Å; Y426-Q430 HydrophobicContact CD2-CG 4.39Å; Y426-Q430 HydrophobicContact CE1-CG 3.89Å; Y426-Q430 HydrophobicContact CE2-CG 3.84Å; Y426-Q430 WeakPolarHBondContact O-CG 3.27Å; Y426-Q430 PolarHBondContact O-N 2.94Å; Y426-Q430 PolarHBondContact OH-NE2 3.47Å; S427-Q430 PolarHBondContact O-N 3.08Å; L428-Q430 VanDerWaalsContact C-N 3.33Å; L428-Q430 PolarHBondContact O-N 3.48Å; Q430-Y433 PolarHBondContact O-N 3.22Å; Q430-R434 WeakPolarHBondContact O-CB 3.48Å; Q430-R434 PolarHBondContact O-N 2.67Å
431C87.3Confident88.7Confident45 Ų4569 Ų6930%0.30431%0.311SS..Hα-helixtrans-61.5-43.1173-73.80000111.7S427 L428 Y433 R434 W435S427-C431 PolarHBondContact O-N 2.85Å; S427-C431 PolarHBondContact O-SG 3.04Å; S427-C431 VanDerWaalsContact O-SG 3.34Å; L428-C431 PolarHBondContact O-N 3.45Å; C431-Y433 VanDerWaalsContact C-N 3.3Å; C431-Y433 PolarHBondContact O-N 3.33Å; C431-R434 PolarHBondContact O-N 3.48Å; C431-W435 HydrophobicContact CB-CE3 4.13Å; C431-W435 HydrophobicContact CB-CZ3 4.24Å; C431-W435 WeakPolarHBondContact O-CB 3.34Å; C431-W435 PolarHBondContact O-N 3.37Å
432C86.5Confident88.2Confident8 Ų869.6 Ų69.65%0.05432%0.315CS..Hα-helixtrans-64.7-35.5176.9-67.70000112.3L428 G429 T442L428-C432 WeakPolarHBondContact O-CB 3.45Å; L428-C432 PolarHBondContact O-N 2.97Å; L428-C432 PolarHBondContact O-SG 2.95Å; G429-C432 PolarHBondContact O-N 3.46Å; C432-T442 PolarHBondContact SG-OG1 3.39Å
433Y84.8Confident87.9Confident85 Ų8571.1 Ų71.133%0.33333%0.326SS..Hα-helixtrans-69.4-44.4174.3171.2-113.3000112.7Y7 H11 G429 Q430 C431 I436Y7-Y433 HydrophobicContact CD1-CE2 4.18Å; Y7-Y433 HydrophobicContact CE1-CD2 4.33Å; Y7-Y433 AromaticContact CE1-CE2 3.47Å; Y7-Y433 HydrophobicContact CE1-CE2 3.47Å; Y7-Y433 VanDerWaalsContact CE1-CE2 3.47Å; Y7-Y433 AromaticContact CE1-CZ 3.66Å; H11-Y433 AromaticContact CD2-CD2 3.6Å; H11-Y433 AromaticContact CE1-CD2 3.93Å; H11-Y433 AromaticContact NE2-CD2 3.54Å; H11-Y433 AromaticContact NE2-CE2 3.99Å; G429-Y433 WeakPolarHBondContact O-CB 3.47Å; G429-Y433 PolarHBondContact O-N 3.3Å; Q430-Y433 PolarHBondContact O-N 3.22Å; C431-Y433 VanDerWaalsContact C-N 3.3Å; C431-Y433 PolarHBondContact O-N 3.33Å; Y433-I436 WeakPolarHBondContact O-CD1 3.23Å; Y433-I436 VanDerWaalsContact O-CG1 3.22Å; Y433-I436 WeakPolarHBondContact O-CG1 3.14Å
434R86Confident87.7Confident202 Ų20274.9 Ų74.976%0.76235%0.349SS*.Hα-helixtrans-78.4-27.4-176.4-173.9161.6147.4108.8-6.2113.3Q430 C431Q430-R434 WeakPolarHBondContact O-CB 3.48Å; Q430-R434 PolarHBondContact O-N 2.67Å; C431-R434 PolarHBondContact O-N 3.48Å
435W85.3Confident87.6Confident132 Ų13278.2 Ų78.250%0.537%0.365SS..THydrogen-bonded Turntrans-116.149.3-178.9-60-30.9000112.3C431 K437 Y438 K439C431-W435 HydrophobicContact CB-CE3 4.13Å; C431-W435 HydrophobicContact CB-CZ3 4.24Å; C431-W435 WeakPolarHBondContact O-CB 3.34Å; C431-W435 PolarHBondContact O-N 3.37Å; W435-K437 PolarHBondContact O-N 2.85Å; W435-K437 VanDerWaalsContact O-N 3.12Å; W435-Y438 HydrophobicContact CB-CD2 4.31Å; W435-Y438 CarbonylContact O-C 3.4Å; W435-Y438 WeakPolarHBondContact O-CA 3.49Å; W435-Y438 PolarHBondContact O-N 2.63Å; W435-K439 PolarHBondContact O-N 3.23Å
436I81.8Confident87.5Confident96 Ų9678.9 Ų78.949%0.49237%0.369SS..G310 helixtrans-51.9-38.1-179.2-71.6156.3000112.5Y433 Y438 K439Y433-I436 WeakPolarHBondContact O-CD1 3.23Å; Y433-I436 VanDerWaalsContact O-CG1 3.22Å; Y433-I436 WeakPolarHBondContact O-CG1 3.14Å; I436-Y438 PolarHBondContact O-N 3.31Å; I436-K439 VanDerWaalsContact O-CB 3.26Å; I436-K439 WeakPolarHBondContact O-CB 3.22Å; I436-K439 PolarHBondContact O-N 3.28Å; I436-K439 VanDerWaalsContact O-N 3.12Å
437K86.4Confident87.6Confident181 Ų18182.9 Ų82.979%0.78739%0.39SS*.G310 helixtrans-57.4-31.2176.7-173.4177.1178.8-178.90112.9W435W435-K437 PolarHBondContact O-N 2.85Å; W435-K437 VanDerWaalsContact O-N 3.12Å
438Y85.6Confident87.9Confident131 Ų13183 Ų8351%0.51440%0.395SS..G310 helixtrans-103.717.9-178-57.9-70.9000113W435 I436 K440 L441 T442W435-Y438 HydrophobicContact CB-CD2 4.31Å; W435-Y438 CarbonylContact O-C 3.4Å; W435-Y438 WeakPolarHBondContact O-CA 3.49Å; W435-Y438 PolarHBondContact O-N 2.63Å; I436-Y438 PolarHBondContact O-N 3.31Å; Y438-K440 PolarHBondContact O-N 2.94Å; Y438-K440 VanDerWaalsContact O-N 3.13Å; Y438-L441 WeakPolarHBondContact O-CA 3.23Å; Y438-L441 WeakPolarHBondContact O-CB 3.38Å; Y438-L441 PolarHBondContact O-N 2.87Å; Y438-T442 PolarHBondContact O-N 3.44Å
439K82.9Confident88.1Confident83 Ų8383 Ų8336%0.36140%0.395SS..Hα-helixtrans-54-35.2-176.6-173.5179.3-176.8-179.90114.2H11 W435 I436 T442 C443H11-K439 WeakPolarHBondContact O-CE 3.26Å; W435-K439 PolarHBondContact O-N 3.23Å; I436-K439 VanDerWaalsContact O-CB 3.26Å; I436-K439 WeakPolarHBondContact O-CB 3.22Å; I436-K439 PolarHBondContact O-N 3.28Å; I436-K439 VanDerWaalsContact O-N 3.12Å; K439-T442 WeakPolarHBondContact CA-OG1 3.31Å; K439-T442 PolarHBondContact O-OG1 3.15Å; K439-C443 WeakPolarHBondContact O-CB 3.34Å; K439-C443 PolarHBondContact O-N 2.94Å
440K87Confident88.4Confident184 Ų18484.8 Ų84.880%0.840%0.404SS*.Hα-helixtrans-65.7-45174.8-71.5-174179.5-1790111.4Y438 C443 V444Y438-K440 PolarHBondContact O-N 2.94Å; Y438-K440 VanDerWaalsContact O-N 3.13Å; K440-C443 PolarHBondContact O-N 3.41Å; K440-V444 WeakPolarHBondContact O-CG2 3.35Å; K440-V444 PolarHBondContact O-N 3.26Å
441L89.3Confident88.9Confident98 Ų9886.1 Ų86.151%0.51342%0.418SS..Hα-helixtrans-64.1-43.4177.7-17963000111.1Y438 C443 V444 M445Y438-L441 WeakPolarHBondContact O-CA 3.23Å; Y438-L441 WeakPolarHBondContact O-CB 3.38Å; Y438-L441 PolarHBondContact O-N 2.87Å; L441-C443 VanDerWaalsContact C-N 3.32Å; L441-C443 PolarHBondContact O-N 3.17Å; L441-V444 PolarHBondContact O-N 3.31Å; L441-M445 HydrophobicContact CD1-CG 4.5Å; L441-M445 HydrophobicContact CG-CE 4.17Å; L441-M445 HydrophobicContact CG-SD 4.47Å; L441-M445 WeakPolarHBondContact O-CG 3.32Å; L441-M445 PolarHBondContact O-N 3.19Å
442T86.5Confident89.3Confident13 Ų1388 Ų888%0.0842%0.423CS..Hα-helixtrans-64-36.6176.460.20000112.4C432 Y438 K439 M445 L446C432-T442 PolarHBondContact SG-OG1 3.39Å; Y438-T442 PolarHBondContact O-N 3.44Å; K439-T442 WeakPolarHBondContact CA-OG1 3.31Å; K439-T442 PolarHBondContact O-OG1 3.15Å; T442-M445 HydrophobicContact CG2-CE 4.07Å; T442-M445 PolarHBondContact O-N 2.87Å; T442-L446 VanDerWaalsContact O-CB 3.29Å; T442-L446 WeakPolarHBondContact O-CB 3.44Å; T442-L446 PolarHBondContact O-N 2.94Å
443C88.6Confident89.8Confident33 Ų3387.8 Ų87.822%0.22342%0.421CS..Hα-helixtrans-65-43.7173-1760000112.3P13 K439 K440 L441 L446 L447P13-C443 HydrophobicContact CB-CB 3.87Å; P13-C443 HydrophobicContact CG-CB 3.91Å; K439-C443 WeakPolarHBondContact O-CB 3.34Å; K439-C443 PolarHBondContact O-N 2.94Å; K440-C443 PolarHBondContact O-N 3.41Å; L441-C443 VanDerWaalsContact C-N 3.32Å; L441-C443 PolarHBondContact O-N 3.17Å; C443-L446 WeakPolarHBondContact O-CB 3.47Å; C443-L446 PolarHBondContact O-N 3.34Å; C443-L447 WeakPolarHBondContact O-CG 3.42Å; C443-L447 PolarHBondContact O-N 3.2Å
444V91.6Very high90.4Very high93 Ų9385.5 Ų85.556%0.56442%0.416SS*.Hα-helixtrans-62-45.1175.3171.30000111.1K440 L441 L446 L447 A448K440-V444 WeakPolarHBondContact O-CG2 3.35Å; K440-V444 PolarHBondContact O-N 3.26Å; L441-V444 PolarHBondContact O-N 3.31Å; V444-L446 VanDerWaalsContact C-N 3.33Å; V444-L446 PolarHBondContact O-N 3.41Å; V444-L447 PolarHBondContact O-N 3.24Å; V444-A448 WeakPolarHBondContact O-CB 3.48Å; V444-A448 PolarHBondContact O-N 3.31Å
445M91.9Very high90.9Very high100 Ų10079.7 Ų79.749%0.49340%0.403SS..Hα-helixtrans-62.9-39.4176.4-69.6-172.9-60.800112.1L441 T442 A448 L449L441-M445 HydrophobicContact CD1-CG 4.5Å; L441-M445 HydrophobicContact CG-CE 4.17Å; L441-M445 HydrophobicContact CG-SD 4.47Å; L441-M445 WeakPolarHBondContact O-CG 3.32Å; L441-M445 PolarHBondContact O-N 3.19Å; T442-M445 HydrophobicContact CG2-CE 4.07Å; T442-M445 PolarHBondContact O-N 2.87Å; M445-A448 PolarHBondContact O-N 2.83Å; M445-L449 WeakPolarHBondContact O-CB 3.33Å; M445-L449 PolarHBondContact O-N 3.3Å
446L92Very high91.4Very high14 Ų1476.2 Ų76.27%0.07339%0.39CS..Hα-helixtrans-61.4-49175.5175.372000111.6P13 L151 F155 L428 T442 C443 V444 A448 L449 L450P13-L446 HydrophobicContact CG-CD2 4.08Å; L151-L446 HydrophobicContact CD1-CD1 3.87Å; L151-L446 HydrophobicContact CD1-CD2 4.18Å; L151-L446 HydrophobicContact CD2-CD1 4.46Å; F155-L446 HydrophobicContact CE2-CD1 3.77Å; F155-L446 HydrophobicContact CZ-CD1 3.46Å; F155-L446 VanDerWaalsContact CZ-CD1 3.46Å; L428-L446 HydrophobicContact CD1-CD1 3.77Å; T442-L446 VanDerWaalsContact O-CB 3.29Å; T442-L446 WeakPolarHBondContact O-CB 3.44Å; T442-L446 PolarHBondContact O-N 2.94Å; C443-L446 WeakPolarHBondContact O-CB 3.47Å; C443-L446 PolarHBondContact O-N 3.34Å; V444-L446 VanDerWaalsContact C-N 3.33Å; V444-L446 PolarHBondContact O-N 3.41Å; L446-A448 VanDerWaalsContact C-N 3.34Å; L446-L449 PolarHBondContact O-N 3.32Å; L446-L450 PolarHBondContact O-N 3.06Å
447L93Very high92.1Very high94 Ų9471.7 Ų71.749%0.49237%0.366SS..Hα-helixtrans-63.9-40.6177.8-71.1172.3000111.3C443 V444 L450 C451C443-L447 WeakPolarHBondContact O-CG 3.42Å; C443-L447 PolarHBondContact O-N 3.2Å; V444-L447 PolarHBondContact O-N 3.24Å; L447-L450 PolarHBondContact O-N 3.13Å; L447-C451 WeakPolarHBondContact O-CB 3.37Å; L447-C451 PolarHBondContact O-N 3.48Å; L447-C451 PolarHBondContact O-SG 2.93Å
448A94.9Very high92.5Very high59 Ų5964 Ų6449%0.48834%0.337SS..Hα-helixtrans-62.1-43.3175.700000112V444 M445 L446 C451 M452V444-A448 WeakPolarHBondContact O-CB 3.48Å; V444-A448 PolarHBondContact O-N 3.31Å; M445-A448 PolarHBondContact O-N 2.83Å; L446-A448 VanDerWaalsContact C-N 3.34Å; A448-C451 PolarHBondContact O-N 3.34Å; A448-M452 WeakPolarHBondContact O-CB 3.43Å; A448-M452 PolarHBondContact O-N 3.27Å
449L94.3Very high93Very high44 Ų4462.1 Ų62.123%0.2334%0.335CS..Hα-helixtrans-61.8-45.9175.2179.160.2000111.3F155 M445 L446 M452 Y453F155-L449 HydrophobicContact CE1-CD2 3.84Å; F155-L449 HydrophobicContact CE1-CG 4.02Å; F155-L449 HydrophobicContact CZ-CD2 3.95Å; M445-L449 WeakPolarHBondContact O-CB 3.33Å; M445-L449 PolarHBondContact O-N 3.3Å; L446-L449 PolarHBondContact O-N 3.32Å; L449-M452 HydrophobicContact CD1-CE 3.55Å; L449-M452 WeakPolarHBondContact O-CB 3.32Å; L449-M452 PolarHBondContact O-N 3.01Å; L449-Y453 HydrophobicContact CD1-CD1 3.92Å; L449-Y453 HydrophobicContact CD1-CE1 3.44Å; L449-Y453 VanDerWaalsContact CD1-CE1 3.44Å; L449-Y453 HydrophobicContact CG-CE1 4.26Å; L449-Y453 WeakPolarHBondContact O-CB 3.41Å; L449-Y453 WeakPolarHBondContact O-CD1 3.48Å; L449-Y453 PolarHBondContact O-N 3.44Å
450L94.9Very high93.6Very high37 Ų3758.7 Ų58.719%0.19432%0.32CS..Hα-helixtrans-63.8-45.8177.8-176.462.6000111.8I154 A158 L446 L447 M452 Y453 V454I154-L450 HydrophobicContact CG2-CD1 3.46Å; I154-L450 VanDerWaalsContact CG2-CD1 3.46Å; I154-L450 HydrophobicContact CG2-CD2 3.71Å; I154-L450 HydrophobicContact CG2-CG 4.25Å; A158-L450 HydrophobicContact CB-CD1 3.82Å; L446-L450 PolarHBondContact O-N 3.06Å; L447-L450 PolarHBondContact O-N 3.13Å; L450-M452 VanDerWaalsContact C-N 3.31Å; L450-M452 PolarHBondContact O-N 2.71Å; L450-Y453 WeakPolarHBondContact O-CB 3.35Å; L450-Y453 PolarHBondContact O-N 3.07Å; L450-Y453 VanDerWaalsContact O-N 3.14Å; L450-V454 WeakPolarHBondContact O-CG2 3.34Å; L450-V454 PolarHBondContact O-N 3.46Å
451C96Very high94Very high77 Ų7750 Ų5052%0.5228%0.282SS..Hα-helixtrans-59.6-43175.1-73.70000111.3L447 A448 Y453 V454 V455L447-C451 WeakPolarHBondContact O-CB 3.37Å; L447-C451 PolarHBondContact O-N 3.48Å; L447-C451 PolarHBondContact O-SG 2.93Å; A448-C451 PolarHBondContact O-N 3.34Å; C451-Y453 VanDerWaalsContact C-N 3.31Å; C451-Y453 PolarHBondContact O-N 2.88Å; C451-V454 PolarHBondContact O-N 3.23Å; C451-V455 WeakPolarHBondContact O-CB 3.45Å; C451-V455 VanDerWaalsContact O-CG2 3.25Å; C451-V455 WeakPolarHBondContact O-CG2 3.3Å; C451-V455 PolarHBondContact O-N 3.3Å
452M95.9Very high94.3Very high85 Ų8549.5 Ų49.542%0.41928%0.277SS..Hα-helixtrans-59.5-43.9174.8-177.5-178.264.500110.9A448 L449 L450 V455 R456A448-M452 WeakPolarHBondContact O-CB 3.43Å; A448-M452 PolarHBondContact O-N 3.27Å; L449-M452 HydrophobicContact CD1-CE 3.55Å; L449-M452 WeakPolarHBondContact O-CB 3.32Å; L449-M452 PolarHBondContact O-N 3.01Å; L450-M452 VanDerWaalsContact C-N 3.31Å; L450-M452 PolarHBondContact O-N 2.71Å; M452-V455 PolarHBondContact O-N 3.47Å; M452-R456 HydrophobicContact CG-CG 4.21Å; M452-R456 VanDerWaalsContact O-CB 3.24Å; M452-R456 WeakPolarHBondContact O-CB 3.42Å; M452-R456 WeakPolarHBondContact O-CG 3.38Å; M452-R456 PolarHBondContact O-N 3.35Å
453Y96.8Very high94.8Very high2 Ų251.6 Ų51.61%0.00829%0.286CS..Hα-helixtrans-61.3-50.4177.7-88.230.5000111.7F155 A158 H159 P160 P331 Y420 L449 L450 C451 V455 R456 C457F155-Y453 HydrophobicContact CD1-CD2 4.06Å; F155-Y453 HydrophobicContact CD1-CE2 4.04Å; A158-Y453 WeakPolarHBondContact O-CB 3.4Å; H159-Y453 AromaticContact CD2-CE2 3.84Å; P160-Y453 HydrophobicContact CG-CD1 4.49Å; P160-Y453 HydrophobicContact CG-CG 4.38Å; P331-Y453 HydrophobicContact CG-CE1 4.36Å; Y420-Y453 PolarHBondContact OH-OH 3.24Å; L449-Y453 HydrophobicContact CD1-CD1 3.92Å; L449-Y453 HydrophobicContact CD1-CE1 3.44Å; L449-Y453 VanDerWaalsContact CD1-CE1 3.44Å; L449-Y453 HydrophobicContact CG-CE1 4.26Å; L449-Y453 WeakPolarHBondContact O-CB 3.41Å; L449-Y453 WeakPolarHBondContact O-CD1 3.48Å; L449-Y453 PolarHBondContact O-N 3.44Å; L450-Y453 WeakPolarHBondContact O-CB 3.35Å; L450-Y453 PolarHBondContact O-N 3.07Å; L450-Y453 VanDerWaalsContact O-N 3.14Å; C451-Y453 VanDerWaalsContact C-N 3.31Å; C451-Y453 PolarHBondContact O-N 2.88Å; Y453-V455 PolarHBondContact O-N 3.27Å; Y453-R456 WeakPolarHBondContact O-CB 3.4Å; Y453-R456 PolarHBondContact O-N 2.94Å; Y453-C457 PolarHBondContact O-N 2.89Å; Y453-C457 PolarHBondContact O-SG 2.8Å; Y453-C457 VanDerWaalsContact O-SG 3.35Å
454V97.2Very high95.1Very high37 Ų3750.3 Ų50.322%0.22428%0.276CS..Hα-helixtrans-59.3-46.6176.8177.60000111.6A158 L450 C451 R456 C457 A458A158-V454 HydrophobicContact CB-CG2 4.11Å; L450-V454 WeakPolarHBondContact O-CG2 3.34Å; L450-V454 PolarHBondContact O-N 3.46Å; C451-V454 PolarHBondContact O-N 3.23Å; V454-R456 VanDerWaalsContact C-N 3.31Å; V454-R456 PolarHBondContact O-N 2.91Å; V454-C457 PolarHBondContact O-N 3.33Å; V454-A458 WeakPolarHBondContact O-CB 3.34Å; V454-A458 PolarHBondContact O-N 3.43Å
455V95.9Very high95.3Very high80 Ų8049.7 Ų49.749%0.48526%0.264SS..Hα-helixtrans-62.3-40.8177.8170.20000110.9C451 M452 Y453 A458 L459C451-V455 WeakPolarHBondContact O-CB 3.45Å; C451-V455 VanDerWaalsContact O-CG2 3.25Å; C451-V455 WeakPolarHBondContact O-CG2 3.3Å; C451-V455 PolarHBondContact O-N 3.3Å; M452-V455 PolarHBondContact O-N 3.47Å; Y453-V455 PolarHBondContact O-N 3.27Å; V455-A458 PolarHBondContact O-N 2.79Å; V455-L459 HydrophobicContact CG1-CD1 3.86Å; V455-L459 HydrophobicContact CG1-CG 4.3Å; V455-L459 WeakPolarHBondContact O-CB 3.49Å; V455-L459 VanDerWaalsContact O-CG 3.29Å; V455-L459 WeakPolarHBondContact O-CG 3.32Å; V455-L459 PolarHBondContact O-N 2.96Å
456R95.9Very high95.5Very high60 Ų6046.1 Ų46.123%0.22625%0.249CC..Hα-helixtrans-64.2-44.7177.2-74.8-75.8142.7-178.3-12.7111.7P160 W332 M452 Y453 V454 L459 R460P160-R456 HydrophobicContact CB-CB 3.94Å; P160-R456 HydrophobicContact CG-CB 3.54Å; W332-R456 VanDerWaalsContact CE2-NH1 3.33Å; M452-R456 HydrophobicContact CG-CG 4.21Å; M452-R456 VanDerWaalsContact O-CB 3.24Å; M452-R456 WeakPolarHBondContact O-CB 3.42Å; M452-R456 WeakPolarHBondContact O-CG 3.38Å; M452-R456 PolarHBondContact O-N 3.35Å; Y453-R456 WeakPolarHBondContact O-CB 3.4Å; Y453-R456 PolarHBondContact O-N 2.94Å; V454-R456 VanDerWaalsContact C-N 3.31Å; V454-R456 PolarHBondContact O-N 2.91Å; R456-L459 PolarHBondContact O-N 3.44Å; R456-R460 VanDerWaalsContact O-CB 3.24Å; R456-R460 WeakPolarHBondContact O-CB 3.44Å; R456-R460 PolarHBondContact O-N 3.39Å
457C97.1Very high95.5Very high0 Ų047.4 Ų47.40%025%0.254CS..Hα-helixtrans-57.9-49.3172.5-68.80000111.2C33 F34 A158 P160 Y453 V454 L459 R460 S461C33-C457 HydrophobicContact CB-CB 3.64Å; C33-C457 CarbonylContact O-C 3.56Å; C33-C457 WeakPolarHBondContact O-CB 3.24Å; F34-C457 HydrophobicContact CE1-CB 4.05Å; F34-C457 HydrophobicContact CZ-CB 4.13Å; A158-C457 PolarHBondContact O-SG 2.66Å; P160-C457 WeakPolarHBondContact CA-SG 3.4Å; Y453-C457 PolarHBondContact O-N 2.89Å; Y453-C457 PolarHBondContact O-SG 2.8Å; Y453-C457 VanDerWaalsContact O-SG 3.35Å; V454-C457 PolarHBondContact O-N 3.33Å; C457-L459 PolarHBondContact O-N 3.32Å; C457-R460 PolarHBondContact O-N 3.18Å; C457-S461 WeakPolarHBondContact O-CB 3.47Å; C457-S461 PolarHBondContact O-N 2.84Å; C457-S461 PolarHBondContact O-OG 3.12Å
458A95.9Very high95.6Very high20 Ų2046.8 Ų46.817%0.16525%0.249CC..Hα-helixtrans-62.3-43.2-177.800000112.2C33 V454 V455 H462C33-A458 WeakPolarHBondContact O-CA 3.42Å; C33-A458 PolarHBondContact O-N 2.87Å; V454-A458 WeakPolarHBondContact O-CB 3.34Å; V454-A458 PolarHBondContact O-N 3.43Å; V455-A458 PolarHBondContact O-N 2.79Å; A458-H462 WeakPolarHBondContact O-CB 3.49Å; A458-H462 PolarHBondContact O-N 2.99Å
459L95.3Very high95.6Very high92 Ų9245.4 Ų45.448%0.48224%0.236SC..Hα-helixtrans-66.1-47.6176.5-73.1173.3000111.9V455 R456 C457 S461 H462 Q463V455-L459 HydrophobicContact CG1-CD1 3.86Å; V455-L459 HydrophobicContact CG1-CG 4.3Å; V455-L459 WeakPolarHBondContact O-CB 3.49Å; V455-L459 VanDerWaalsContact O-CG 3.29Å; V455-L459 WeakPolarHBondContact O-CG 3.32Å; V455-L459 PolarHBondContact O-N 2.96Å; R456-L459 PolarHBondContact O-N 3.44Å; C457-L459 PolarHBondContact O-N 3.32Å; L459-S461 VanDerWaalsContact C-N 3.33Å; L459-S461 PolarHBondContact O-N 3.39Å; L459-H462 PolarHBondContact O-N 2.77Å; L459-Q463 WeakPolarHBondContact O-CG 3.44Å; L459-Q463 PolarHBondContact O-N 3.3Å
460R95.7Very high95.6Very high11 Ų1143.3 Ų43.34%0.04223%0.225CC..Hα-helixtrans-64.3-41179.5-17459.2175.5155.63.8110.3T163 L334 F336 E410 R456 C457 H462 Q463 W464 S473T163-R460 HydrophobicContact CG2-CB 3.79Å; T163-R460 HydrophobicContact CG2-CG 3.46Å; T163-R460 VanDerWaalsContact CG2-CG 3.46Å; L334-R460 HydrophobicContact CD1-CG 3.98Å; F336-R460 VanDerWaalsContact N-NH2 3.2Å; E410-R460 IonicContact OE1-CZ 2.9Å; E410-R460 IonicContact OE1-NE 3.76Å; E410-R460 PolarHBondContact OE1-NE 2.93Å; E410-R460 IonicContact OE1-NH2 3.26Å; E410-R460 PolarHBondContact OE1-NH2 3.23Å; R456-R460 VanDerWaalsContact O-CB 3.24Å; R456-R460 WeakPolarHBondContact O-CB 3.44Å; R456-R460 PolarHBondContact O-N 3.39Å; C457-R460 PolarHBondContact O-N 3.18Å; R460-H462 VanDerWaalsContact C-N 3.31Å; R460-H462 PolarHBondContact O-N 3.21Å; R460-Q463 WeakPolarHBondContact O-CB 3.48Å; R460-Q463 PolarHBondContact O-N 2.73Å; R460-W464 VanDerWaalsContact O-CD1 3.28Å; R460-W464 PolarHBondContact O-N 2.68Å; R460-S473 PolarHBondContact NH1-OG 3.2Å
461S96Very high95.6Very high0 Ų041.8 Ų41.80%022%0.217CC..Hα-helixtrans-65.4-37.4179.4-56.70000111.3F34 T163 C457 L459 Q463 W464F34-S461 WeakPolarHBondContact CD1-OG 3.45Å; T163-S461 WeakPolarHBondContact CG2-OG 3.35Å; C457-S461 WeakPolarHBondContact O-CB 3.47Å; C457-S461 PolarHBondContact O-N 2.84Å; C457-S461 PolarHBondContact O-OG 3.12Å; L459-S461 VanDerWaalsContact C-N 3.33Å; L459-S461 PolarHBondContact O-N 3.39Å; S461-Q463 VanDerWaalsContact C-N 3.28Å; S461-Q463 PolarHBondContact O-N 2.85Å; S461-W464 PolarHBondContact O-N 3.28Å; S461-W464 VanDerWaalsContact O-N 3.16Å
462H95.5Very high95.5Very high88 Ų8840.7 Ų40.741%0.40721%0.21SC..Hα-helixtrans-61.9-36.2172.8-174.9-80.3000112.2A458 L459 R460 W464 R465A458-H462 WeakPolarHBondContact O-CB 3.49Å; A458-H462 PolarHBondContact O-N 2.99Å; L459-H462 PolarHBondContact O-N 2.77Å; R460-H462 VanDerWaalsContact C-N 3.31Å; R460-H462 PolarHBondContact O-N 3.21Å; H462-W464 PolarHBondContact O-N 3.03Å; H462-R465 PolarHBondContact NE2-NH1 3.38Å; H462-R465 VanDerWaalsContact NE2-NH1 3.1Å; H462-R465 WeakPolarHBondContact O-CB 3.5Å; H462-R465 WeakPolarHBondContact O-CG 3.5Å; H462-R465 PolarHBondContact O-N 3.36Å; H462-R465 VanDerWaalsContact O-N 3.16Å
463Q95.4Very high95.5Very high58 Ų5837.4 Ų37.427%0.27120%0.195SC..Hα-helixtrans-63.5-30176.5-65.4167.8-10.300112.3L459 R460 S461 R465 S469 L470 S473L459-Q463 WeakPolarHBondContact O-CG 3.44Å; L459-Q463 PolarHBondContact O-N 3.3Å; R460-Q463 WeakPolarHBondContact O-CB 3.48Å; R460-Q463 PolarHBondContact O-N 2.73Å; S461-Q463 VanDerWaalsContact C-N 3.28Å; S461-Q463 PolarHBondContact O-N 2.85Å; Q463-R465 VanDerWaalsContact C-N 3.25Å; Q463-R465 PolarHBondContact O-N 3.23Å; Q463-S469 CarbonylContact O-C 3.36Å; Q463-S469 WeakPolarHBondContact O-CB 3.3Å; Q463-S469 PolarHBondContact O-OG 3.34Å; Q463-L470 VanDerWaalsContact O-CA 3.27Å; Q463-L470 WeakPolarHBondContact O-CA 3.45Å; Q463-L470 WeakPolarHBondContact O-CB 3.38Å; Q463-L470 PolarHBondContact O-N 3.06Å; Q463-S473 PolarHBondContact OE1-OG 3.14Å
464W95.7Very high95.3Very high5 Ų537.3 Ų37.32%0.01920%0.195CC..THydrogen-bonded Turntrans-76.1-3176.7-78.490.7000114.3V43 E164 A167 F336 R460 S461 H462 S466 L470V43-W464 HydrophobicContact CG2-CE3 3.79Å; V43-W464 HydrophobicContact CG2-CZ3 4.28Å; V43-W464 WeakPolarHBondContact CG2-O 3.38Å; E164-W464 HydrophobicContact CB-CH2 4.36Å; E164-W464 HydrophobicContact CB-CZ2 3.77Å; E164-W464 HydrophobicContact CG-CH2 3.73Å; E164-W464 HydrophobicContact CG-CZ2 3.63Å; A167-W464 HydrophobicContact CB-CB 3.61Å; A167-W464 HydrophobicContact CB-CG 3.86Å; F336-W464 HydrophobicContact CB-CH2 4.16Å; F336-W464 HydrophobicContact CB-CZ2 4.05Å; R460-W464 VanDerWaalsContact O-CD1 3.28Å; R460-W464 PolarHBondContact O-N 2.68Å; S461-W464 PolarHBondContact O-N 3.28Å; S461-W464 VanDerWaalsContact O-N 3.16Å; H462-W464 PolarHBondContact O-N 3.03Å; W464-S466 VanDerWaalsContact C-N 3.34Å; W464-S466 PolarHBondContact O-N 3.3Å; W464-L470 HydrophobicContact CD2-CD1 3.74Å; W464-L470 HydrophobicContact CD2-CD2 4.2Å; W464-L470 HydrophobicContact CE3-CD1 4.22Å; W464-L470 HydrophobicContact CE3-CD2 3.8Å; W464-L470 HydrophobicContact CG-CD1 4.02Å; W464-L470 HydrophobicContact CH2-CD2 4.23Å; W464-L470 HydrophobicContact CZ2-CD1 4.11Å; W464-L470 HydrophobicContact CZ3-CD2 3.82Å
465R95.9Very high95.1Very high80 Ų8037.2 Ų37.230%0.30219%0.193SC..THydrogen-bonded Turntrans-69-27-179-69.2175.781.1-159.51.9114.3N36 D39 G40 E41 H462 Q463N36-R465 VanDerWaalsContact O-CD 3.24Å; N36-R465 WeakPolarHBondContact O-CD 3.5Å; D39-R465 IonicContact OD1-CZ 3.67Å; D39-R465 VanDerWaalsContact OD1-CZ 3.29Å; D39-R465 IonicContact OD1-NE 3.23Å; D39-R465 PolarHBondContact OD1-NE 2.91Å; D39-R465 IonicContact OD1-NH2 3.01Å; D39-R465 PolarHBondContact OD1-NH2 2.86Å; D39-R465 IonicContact OD2-CZ 3.77Å; D39-R465 IonicContact OD2-NH2 3.34Å; D39-R465 PolarHBondContact OD2-NH2 3.4Å; G40-R465 WeakPolarHBondContact CA-O 3.31Å; E41-R465 PolarHBondContact N-O 3.07Å; H462-R465 PolarHBondContact NE2-NH1 3.38Å; H462-R465 VanDerWaalsContact NE2-NH1 3.1Å; H462-R465 WeakPolarHBondContact O-CB 3.5Å; H462-R465 WeakPolarHBondContact O-CG 3.5Å; H462-R465 PolarHBondContact O-N 3.36Å; H462-R465 VanDerWaalsContact O-N 3.16Å; Q463-R465 VanDerWaalsContact C-N 3.25Å; Q463-R465 PolarHBondContact O-N 3.23Å
466S95.4Very high94.8Very high25 Ų2538.1 Ų38.118%0.17520%0.203CC..SBendtrans-147.2153.3-179.872.70000111.2W464 Q468 S469 L470W464-S466 VanDerWaalsContact C-N 3.34Å; W464-S466 PolarHBondContact O-N 3.3Å; S466-Q468 PolarHBondContact O-N 3.25Å; S466-S469 PolarHBondContact N-OG 3.37Å; S466-S469 PolarHBondContact O-N 3.11Å; S466-S469 PolarHBondContact O-OG 2.89Å; S466-S469 PolarHBondContact OG-N 3.09Å; S466-S469 VanDerWaalsContact OG-N 3.13Å; S466-S469 PolarHBondContact OG-OG 3.25Å; S466-L470 WeakPolarHBondContact O-CB 3.28Å; S466-L470 PolarHBondContact O-N 3.31Å
467E93.8Very high94.5Very high41 Ų4136.2 Ų36.219%0.19220%0.198CC..Hα-helixtrans-60-35.4176.6-69.6-161.313900111.4V43 F44 L470 F471 N491V43-E467 HydrophobicContact CB-CG 3.85Å; V43-E467 HydrophobicContact CG1-CG 3.93Å; V43-E467 VanDerWaalsContact CG1-N 3.33Å; F44-E467 PolarHBondContact N-OE1 2.91Å; E467-L470 PolarHBondContact O-N 3.35Å; E467-F471 HydrophobicContact CB-CD2 4.14Å; E467-F471 HydrophobicContact CB-CE2 3.71Å; E467-F471 HydrophobicContact CB-CZ 4.25Å; E467-F471 HydrophobicContact CG-CE2 4.17Å; E467-F471 HydrophobicContact CG-CZ 4.32Å; E467-F471 WeakPolarHBondContact O-CB 3.24Å; E467-F471 WeakPolarHBondContact O-CD2 3.37Å; E467-F471 WeakPolarHBondContact O-CG 3.37Å; E467-F471 PolarHBondContact O-N 2.93Å; E467-N491 VanDerWaalsContact C-ND2 3.26Å; E467-N491 PolarHBondContact O-ND2 3.49Å
468Q93.3Very high94.1Very high81 Ų8136.5 Ų36.538%0.37920%0.2SC..Hα-helixtrans-61.4-55177.6-173.8-164.14.800111.3S466 L470 S472 N491S466-Q468 PolarHBondContact O-N 3.25Å; Q468-L470 VanDerWaalsContact C-N 3.28Å; Q468-L470 PolarHBondContact O-N 3.08Å; Q468-S472 VanDerWaalsContact O-CB 3.24Å; Q468-S472 WeakPolarHBondContact O-CB 3.32Å; Q468-S472 PolarHBondContact O-N 3.19Å; Q468-S472 PolarHBondContact O-OG 3.04Å; Q468-S472 VanDerWaalsContact O-OG 3.09Å; Q468-N491 WeakPolarHBondContact CA-ND2 3.48Å; Q468-N491 PolarHBondContact N-ND2 2.81Å
469S94.9Very high93.9Very high31 Ų3138.8 Ų38.822%0.21721%0.213CC..Hα-helixtrans-62.5-38.9-178.9530000111.5Q463 S466 S473Q463-S469 CarbonylContact O-C 3.36Å; Q463-S469 WeakPolarHBondContact O-CB 3.3Å; Q463-S469 PolarHBondContact O-OG 3.34Å; S466-S469 PolarHBondContact N-OG 3.37Å; S466-S469 PolarHBondContact O-N 3.11Å; S466-S469 PolarHBondContact O-OG 2.89Å; S466-S469 PolarHBondContact OG-N 3.09Å; S466-S469 VanDerWaalsContact OG-N 3.13Å; S466-S469 PolarHBondContact OG-OG 3.25Å; S469-S473 VanDerWaalsContact O-CB 3.25Å; S469-S473 WeakPolarHBondContact O-CB 3.5Å; S469-S473 PolarHBondContact O-N 3.02Å; S469-S473 PolarHBondContact O-OG 3.29Å
470L95.5Very high93.6Very high0 Ų039.3 Ų39.30%022%0.216CC..Hα-helixtrans-64.7-53.5-178.9-174.660.7000110.8V43 F44 F336 Q463 W464 S466 E467 Q468 S473 A474V43-L470 HydrophobicContact CB-CD2 4.42Å; V43-L470 HydrophobicContact CG2-CD2 4.08Å; F44-L470 HydrophobicContact CB-CD2 3.96Å; F336-L470 HydrophobicContact CB-CD1 3.98Å; F336-L470 HydrophobicContact CB-CD2 4.27Å; F336-L470 HydrophobicContact CB-CG 4.17Å; F336-L470 HydrophobicContact CD1-CD1 4.46Å; F336-L470 HydrophobicContact CD1-CG 4.13Å; F336-L470 HydrophobicContact CG-CD1 4.48Å; F336-L470 HydrophobicContact CG-CD2 4.41Å; F336-L470 HydrophobicContact CG-CG 4.2Å; Q463-L470 VanDerWaalsContact O-CA 3.27Å; Q463-L470 WeakPolarHBondContact O-CA 3.45Å; Q463-L470 WeakPolarHBondContact O-CB 3.38Å; Q463-L470 PolarHBondContact O-N 3.06Å; W464-L470 HydrophobicContact CD2-CD1 3.74Å; W464-L470 HydrophobicContact CD2-CD2 4.2Å; W464-L470 HydrophobicContact CE3-CD1 4.22Å; W464-L470 HydrophobicContact CE3-CD2 3.8Å; W464-L470 HydrophobicContact CG-CD1 4.02Å; W464-L470 HydrophobicContact CH2-CD2 4.23Å; W464-L470 HydrophobicContact CZ2-CD1 4.11Å; W464-L470 HydrophobicContact CZ3-CD2 3.82Å; S466-L470 WeakPolarHBondContact O-CB 3.28Å; S466-L470 PolarHBondContact O-N 3.31Å; E467-L470 PolarHBondContact O-N 3.35Å; Q468-L470 VanDerWaalsContact C-N 3.28Å; Q468-L470 PolarHBondContact O-N 3.08Å; L470-S473 PolarHBondContact O-N 3.05Å; L470-S473 PolarHBondContact O-OG 2.96Å; L470-A474 PolarHBondContact O-N 3.39Å
471F95.1Very high93.4Very high5 Ų538.8 Ų38.82%0.02221%0.214CC..Hα-helixtrans-71.4-38.5-176.9-56.2-28.9000112.4F44 F336 E467 S473 A474 N487 V488 N491F44-F471 HydrophobicContact CB-CE1 4.17Å; F44-F471 HydrophobicContact CB-CZ 4.31Å; F44-F471 AromaticContact CD2-CE1 3.7Å; F44-F471 HydrophobicContact CD2-CE1 3.7Å; F44-F471 AromaticContact CD2-CZ 3.99Å; F44-F471 HydrophobicContact CD2-CZ 3.99Å; F44-F471 HydrophobicContact CG-CE1 4.25Å; F336-F471 HydrophobicContact CD1-CD1 4.11Å; F336-F471 HydrophobicContact CD2-CD1 4.46Å; F336-F471 HydrophobicContact CD2-CE1 4.24Å; F336-F471 AromaticContact CE1-CD1 3.51Å; F336-F471 HydrophobicContact CE1-CD1 3.51Å; F336-F471 HydrophobicContact CE1-CE1 4.2Å; F336-F471 HydrophobicContact CE1-CG 4.47Å; F336-F471 AromaticContact CE2-CD1 3.93Å; F336-F471 HydrophobicContact CE2-CD1 3.93Å; F336-F471 AromaticContact CE2-CE1 3.78Å; F336-F471 HydrophobicContact CE2-CE1 3.78Å; F336-F471 AromaticContact CZ-CD1 3.42Å; F336-F471 HydrophobicContact CZ-CD1 3.42Å; F336-F471 VanDerWaalsContact CZ-CD1 3.42Å; F336-F471 AromaticContact CZ-CE1 3.77Å; F336-F471 HydrophobicContact CZ-CE1 3.77Å; F336-F471 HydrophobicContact CZ-CG 4.44Å; E467-F471 HydrophobicContact CB-CD2 4.14Å; E467-F471 HydrophobicContact CB-CE2 3.71Å; E467-F471 HydrophobicContact CB-CZ 4.25Å; E467-F471 HydrophobicContact CG-CE2 4.17Å; E467-F471 HydrophobicContact CG-CZ 4.32Å; E467-F471 WeakPolarHBondContact O-CB 3.24Å; E467-F471 WeakPolarHBondContact O-CD2 3.37Å; E467-F471 WeakPolarHBondContact O-CG 3.37Å; E467-F471 PolarHBondContact O-N 2.93Å; F471-S473 VanDerWaalsContact C-N 3.34Å; F471-S473 PolarHBondContact O-N 3.25Å; F471-A474 WeakPolarHBondContact O-CB 3.28Å; F471-A474 PolarHBondContact O-N 3.44Å; F471-N487 HydrophobicContact CB-CB 4.31Å; F471-N487 HydrophobicContact CD1-CB 4.21Å; F471-N487 HydrophobicContact CD2-CB 3.48Å; F471-N487 VanDerWaalsContact CD2-CB 3.48Å; F471-N487 HydrophobicContact CE1-CB 4.41Å; F471-N487 HydrophobicContact CE2-CB 3.72Å; F471-N487 HydrophobicContact CG-CB 3.75Å; F471-N487 HydrophobicContact CZ-CB 4.19Å; F471-V488 HydrophobicContact CB-CG2 3.78Å; F471-N491 WeakPolarHBondContact CD2-ND2 3.32Å
472S94.1Very high93.3Very high53 Ų5338.8 Ų38.837%0.37121%0.214SC..Hα-helixtrans-66.1-35.7175.7-64.30000112.5Q468 A474 L475Q468-S472 VanDerWaalsContact O-CB 3.24Å; Q468-S472 WeakPolarHBondContact O-CB 3.32Å; Q468-S472 PolarHBondContact O-N 3.19Å; Q468-S472 PolarHBondContact O-OG 3.04Å; Q468-S472 VanDerWaalsContact O-OG 3.09Å; S472-A474 PolarHBondContact O-N 3.37Å; S472-L475 WeakPolarHBondContact O-CB 3.34Å; S472-L475 PolarHBondContact O-N 2.93Å
473S94.5Very high93.2Very high16 Ų1637.1 Ų37.111%0.11221%0.205CC..Hα-helixtrans-62-34.5175.174.30000112.3R460 Q463 S469 L470 F471 L475 S476R460-S473 PolarHBondContact NH1-OG 3.2Å; Q463-S473 PolarHBondContact OE1-OG 3.14Å; S469-S473 VanDerWaalsContact O-CB 3.25Å; S469-S473 WeakPolarHBondContact O-CB 3.5Å; S469-S473 PolarHBondContact O-N 3.02Å; S469-S473 PolarHBondContact O-OG 3.29Å; L470-S473 PolarHBondContact O-N 3.05Å; L470-S473 PolarHBondContact O-OG 2.96Å; F471-S473 VanDerWaalsContact C-N 3.34Å; F471-S473 PolarHBondContact O-N 3.25Å; S473-L475 PolarHBondContact O-N 3.43Å; S473-S476 PolarHBondContact O-N 2.81Å; S473-S476 PolarHBondContact O-OG 2.91Å
474A93.2Very high93.2Very high0 Ų034.4 Ų34.40%019%0.192CC..Hα-helixtrans-66-23.8-179.700000113.1F336 L470 F471 S472 S476 V477 C478 V484F336-A474 HydrophobicContact CD1-CB 3.72Å; F336-A474 HydrophobicContact CE1-CB 3.43Å; F336-A474 VanDerWaalsContact CE1-CB 3.43Å; L470-A474 PolarHBondContact O-N 3.39Å; F471-A474 WeakPolarHBondContact O-CB 3.28Å; F471-A474 PolarHBondContact O-N 3.44Å; S472-A474 PolarHBondContact O-N 3.37Å; A474-S476 PolarHBondContact O-N 3.48Å; A474-V477 HydrophobicContact CB-CG2 4.45Å; A474-V477 VanDerWaalsContact O-CG2 3.26Å; A474-V477 WeakPolarHBondContact O-CG2 3.4Å; A474-V477 PolarHBondContact O-N 2.86Å; A474-C478 PolarHBondContact O-N 3.39Å; A474-V484 HydrophobicContact CB-CB 4.43Å; A474-V484 HydrophobicContact CB-CG1 3.77Å; A474-V484 HydrophobicContact CB-CG2 3.7Å
475L92.6Very high93.2Very high35 Ų3535 Ų3518%0.18320%0.196CC..THydrogen-bonded Turntrans-61.9-32.4176.6-70.6170.4000112.7S472 S473 V477 P479 V484 V488 Y504S472-L475 WeakPolarHBondContact O-CB 3.34Å; S472-L475 PolarHBondContact O-N 2.93Å; S473-L475 PolarHBondContact O-N 3.43Å; L475-V477 VanDerWaalsContact C-N 3.32Å; L475-P479 WeakPolarHBondContact O-CA 3.3Å; L475-P479 WeakPolarHBondContact O-CB 3.36Å; L475-V484 HydrophobicContact CD2-CG1 3.64Å; L475-V484 HydrophobicContact CG-CG1 3.87Å; L475-V488 HydrophobicContact CD1-CG1 4.36Å; L475-V488 HydrophobicContact CD1-CG2 4.04Å; L475-V488 HydrophobicContact CG-CG2 4.24Å; L475-Y504 HydrophobicContact CD1-CE1 3.81Å; L475-Y504 HydrophobicContact CD2-CE1 4.17Å
476S90.7Very high93.3Very high99 Ų9932.7 Ų32.769%0.69219%0.187SC*.THydrogen-bonded Turntrans-75.7-20.217966.90000114S473 A474S473-S476 PolarHBondContact O-N 2.81Å; S473-S476 PolarHBondContact O-OG 2.91Å; A474-S476 PolarHBondContact O-N 3.48Å
477V89Confident93.3Very high21 Ų2132.2 Ų32.213%0.12718%0.183CC..THydrogen-bonded Turntrans-107.8-44-174.4-69.50000111.1W333 C335 A474 L475 P479W333-V477 PolarHBondContact NE1-O 3.46Å; C335-V477 HydrophobicContact CB-CG2 3.97Å; A474-V477 HydrophobicContact CB-CG2 4.45Å; A474-V477 VanDerWaalsContact O-CG2 3.26Å; A474-V477 WeakPolarHBondContact O-CG2 3.4Å; A474-V477 PolarHBondContact O-N 2.86Å; L475-V477 VanDerWaalsContact C-N 3.32Å; V477-P479 VanDerWaalsContact O-CD 3.31Å; V477-P479 WeakPolarHBondContact O-CD 3.07Å
478C89.4Confident93.5Very high6 Ų630.5 Ų30.54%0.04118%0.175CC..  trans-123.362.6-179.4-60.80000110.6C335 A474 L480 N481C335-C478 VanDerWaalsContact SG-SG 3.62Å; A474-C478 PolarHBondContact O-N 3.39Å; C478-L480 PolarHBondContact O-N 2.69Å; C478-L480 VanDerWaalsContact O-N 3.1Å; C478-N481 HydrophobicContact CB-CB 3.95Å; C478-N481 VanDerWaalsContact O-CB 3.3Å; C478-N481 WeakPolarHBondContact O-CB 3.3Å; C478-N481 PolarHBondContact O-N 3.26Å
479P90.6Very high93.6Very high68 Ų6826.7 Ų26.744%0.44216%0.157SC..THydrogen-bonded Turntrans-64.9-16-177.126.8-35.4000113.6L475 V477 H485L475-P479 WeakPolarHBondContact O-CA 3.3Å; L475-P479 WeakPolarHBondContact O-CB 3.36Å; V477-P479 VanDerWaalsContact O-CD 3.31Å; V477-P479 WeakPolarHBondContact O-CD 3.07Å; P479-H485 PolarHBondContact O-NE2 2.82Å
480L90Very high93.7Very high103 Ų10328.8 Ų28.854%0.53916%0.162SC..THydrogen-bonded Turntrans-96.36.7177.9-57.6-179.4000113C478 A482 L511C478-L480 PolarHBondContact O-N 2.69Å; C478-L480 VanDerWaalsContact O-N 3.1Å; L480-A482 PolarHBondContact O-N 2.86Å; L480-L511 HydrophobicContact CB-CD2 4.33Å; L480-L511 HydrophobicContact CD2-CD2 3.99Å
481N91.7Very high93.7Very high0 Ų029.7 Ų29.70%017%0.167CC..  trans-83.9112.1177.7-172.7-33.2000110.9D337 S339 C342 C478 K483 V484 H485D337-N481 PolarHBondContact O-ND2 2.91Å; S339-N481 PolarHBondContact O-ND2 3.46Å; C342-N481 WeakPolarHBondContact SG-CB 3.33Å; C342-N481 PolarHBondContact SG-ND2 2.94Å; C478-N481 HydrophobicContact CB-CB 3.95Å; C478-N481 VanDerWaalsContact O-CB 3.3Å; C478-N481 WeakPolarHBondContact O-CB 3.3Å; C478-N481 PolarHBondContact O-N 3.26Å; N481-K483 VanDerWaalsContact C-N 3.29Å; N481-K483 PolarHBondContact O-N 2.79Å; N481-K483 WeakPolarHBondContact OD1-CA 3.26Å; N481-K483 VanDerWaalsContact OD1-CB 3.32Å; N481-K483 WeakPolarHBondContact OD1-CB 3.34Å; N481-K483 PolarHBondContact OD1-N 3.2Å; N481-V484 HydrophobicContact CB-CB 3.98Å; N481-V484 HydrophobicContact CB-CG2 3.63Å; N481-V484 WeakPolarHBondContact O-CB 3.24Å; N481-V484 PolarHBondContact O-N 3.47Å; N481-V484 PolarHBondContact OD1-N 3Å; N481-H485 PolarHBondContact O-CD2 2.85Å; N481-H485 VanDerWaalsContact O-CD2 3.3Å; N481-H485 PolarHBondContact O-N 3.29Å
482A93.9Very high93.7Very high0 Ų031.2 Ų31.20%018%0.175CC..Hα-helixtrans-60.1-35.3178.700000113.5M340 L480 H485 Y486 A508 L511 H512 Y515M340-A482 HydrophobicContact CB-CB 4.33Å; M340-A482 HydrophobicContact SD-CB 4.31Å; L480-A482 PolarHBondContact O-N 2.86Å; A482-H485 PolarHBondContact O-N 2.76Å; A482-Y486 WeakPolarHBondContact O-CB 3.32Å; A482-Y486 PolarHBondContact O-N 3.45Å; A482-A508 WeakPolarHBondContact CB-O 3.41Å; A482-A508 WeakPolarHBondContact O-CB 3.42Å; A482-L511 HydrophobicContact CB-CB 3.92Å; A482-H512 HydrophobicContact CB-CB 3.55Å; A482-Y515 HydrophobicContact CB-CD1 4.08Å; A482-Y515 HydrophobicContact CB-CE1 4.4Å
483K93.6Very high93.8Very high53 Ų5329.9 Ų29.923%0.2317%0.167CC..Hα-helixtrans-69.5-33178.3-177.7174.9178.8-171.60112.6D337 M340 N481 N487 Y515D337-K483 VanDerWaalsContact OD2-CD 3.26Å; D337-K483 WeakPolarHBondContact OD2-CD 3.34Å; D337-K483 WeakPolarHBondContact OD2-CE 3.47Å; D337-K483 IonicContact OD2-NZ 2.89Å; D337-K483 PolarHBondContact OD2-NZ 3.04Å; M340-K483 HydrophobicContact CB-CB 4.37Å; M340-K483 HydrophobicContact CG-CB 3.91Å; N481-K483 VanDerWaalsContact C-N 3.29Å; N481-K483 PolarHBondContact O-N 2.79Å; N481-K483 WeakPolarHBondContact OD1-CA 3.26Å; N481-K483 VanDerWaalsContact OD1-CB 3.32Å; N481-K483 WeakPolarHBondContact OD1-CB 3.34Å; N481-K483 PolarHBondContact OD1-N 3.2Å; K483-N487 VanDerWaalsContact O-CB 3.31Å; K483-N487 WeakPolarHBondContact O-CB 3.49Å; K483-N487 PolarHBondContact O-N 3.18Å; K483-Y515 HydrophobicContact CB-CE1 4.49Å
484V94.6Very high93.7Very high0 Ų034.6 Ų34.60%019%0.191CC..Hα-helixtrans-62.5-51.3172.1172.40000110.3F336 A474 L475 N481 Y486 N487 V488F336-V484 HydrophobicContact CE1-CG2 3.94Å; F336-V484 HydrophobicContact CZ-CG2 4.03Å; A474-V484 HydrophobicContact CB-CB 4.43Å; A474-V484 HydrophobicContact CB-CG1 3.77Å; A474-V484 HydrophobicContact CB-CG2 3.7Å; L475-V484 HydrophobicContact CD2-CG1 3.64Å; L475-V484 HydrophobicContact CG-CG1 3.87Å; N481-V484 HydrophobicContact CB-CB 3.98Å; N481-V484 HydrophobicContact CB-CG2 3.63Å; N481-V484 WeakPolarHBondContact O-CB 3.24Å; N481-V484 PolarHBondContact O-N 3.47Å; N481-V484 PolarHBondContact OD1-N 3Å; V484-Y486 PolarHBondContact O-N 3.32Å; V484-N487 PolarHBondContact O-N 3.32Å; V484-V488 WeakPolarHBondContact O-CG2 3.38Å; V484-V488 PolarHBondContact O-N 2.8Å
485H96.6Very high93.7Very high18 Ų1842 Ų428%0.08322%0.219CC..Hα-helixtrans-60.8-44177.9-73.6-78.5000111.9P479 N481 A482 N487 V488 G489 Y504 A508 L511P479-H485 PolarHBondContact O-NE2 2.82Å; N481-H485 PolarHBondContact O-CD2 2.85Å; N481-H485 VanDerWaalsContact O-CD2 3.3Å; N481-H485 PolarHBondContact O-N 3.29Å; A482-H485 PolarHBondContact O-N 2.76Å; H485-N487 PolarHBondContact O-N 3.23Å; H485-V488 PolarHBondContact O-N 3.25Å; H485-G489 PolarHBondContact O-N 3.34Å; H485-Y504 HydrophobicContact CB-CD1 4.45Å; H485-Y504 AromaticContact ND1-CD1 3.41Å; H485-Y504 WeakPolarHBondContact ND1-CD1 3.46Å; H485-Y504 AromaticContact ND1-CE1 3.86Å; H485-Y504 WeakPolarHBondContact O-CB 3.34Å; H485-A508 HydrophobicContact CB-CB 3.95Å; H485-L511 WeakPolarHBondContact CD2-CD1 3.34Å
486Y96.8Very high93.8Very high31 Ų3143.1 Ų43.112%0.12224%0.239CC..Hα-helixtrans-56.8-49.5175.3166.7-98.8000112.2A482 V484 V488 G489 K490 Y505 Y515 H517 A518 N521A482-Y486 WeakPolarHBondContact O-CB 3.32Å; A482-Y486 PolarHBondContact O-N 3.45Å; V484-Y486 PolarHBondContact O-N 3.32Å; Y486-V488 PolarHBondContact O-N 2.97Å; Y486-G489 PolarHBondContact O-N 3.07Å; Y486-K490 WeakPolarHBondContact O-CB 3.21Å; Y486-K490 PolarHBondContact O-N 3.23Å; Y486-Y505 AromaticContact CD2-CD1 3.94Å; Y486-Y505 HydrophobicContact CD2-CD1 3.94Å; Y486-Y505 AromaticContact CD2-CE1 3.58Å; Y486-Y505 HydrophobicContact CD2-CE1 3.58Å; Y486-Y505 AromaticContact CE2-CE1 3.91Å; Y486-Y505 HydrophobicContact CE2-CE1 3.91Å; Y486-Y505 HydrophobicContact CG-CE1 4.41Å; Y486-Y505 WeakPolarHBondContact O-CE1 3.49Å; Y486-Y515 HydrophobicContact CD1-CE1 4.42Å; Y486-Y515 AromaticContact CD1-CZ 4Å; Y486-Y515 VanDerWaalsContact CD1-OH 3.26Å; Y486-Y515 WeakPolarHBondContact CD1-OH 3.4Å; Y486-Y515 HydrophobicContact CD2-CE1 4.45Å; Y486-Y515 AromaticContact CG-CE1 3.89Å; Y486-Y515 HydrophobicContact CG-CE1 3.89Å; Y486-Y515 AromaticContact CG-CZ 3.84Å; Y486-H517 HydrophobicContact CE2-CB 4.05Å; Y486-A518 HydrophobicContact CD2-CB 3.77Å; Y486-N521 WeakPolarHBondContact CE2-ND2 3.33Å; Y486-N521 PolarHBondContact OH-ND2 2.95Å
487N95.9Very high94Very high16 Ų1642 Ų429%0.08623%0.225CC..Hα-helixtrans-67.6-35.7-177.9-80-15.4000112.5F471 K483 V484 H485 K490 N491F471-N487 HydrophobicContact CB-CB 4.31Å; F471-N487 HydrophobicContact CD1-CB 4.21Å; F471-N487 HydrophobicContact CD2-CB 3.48Å; F471-N487 VanDerWaalsContact CD2-CB 3.48Å; F471-N487 HydrophobicContact CE1-CB 4.41Å; F471-N487 HydrophobicContact CE2-CB 3.72Å; F471-N487 HydrophobicContact CG-CB 3.75Å; F471-N487 HydrophobicContact CZ-CB 4.19Å; K483-N487 VanDerWaalsContact O-CB 3.31Å; K483-N487 WeakPolarHBondContact O-CB 3.49Å; K483-N487 PolarHBondContact O-N 3.18Å; V484-N487 PolarHBondContact O-N 3.32Å; H485-N487 PolarHBondContact O-N 3.23Å; N487-K490 PolarHBondContact O-N 3.36Å; N487-N491 PolarHBondContact O-N 2.84Å; N487-N491 VanDerWaalsContact O-N 3.08Å
488V96.7Very high94.3Very high5 Ų543.1 Ų43.13%0.0323%0.232CC..Hα-helixtrans-65.4-43.9171.5173.20000110.9F471 L475 V484 H485 Y486 K490 N491 L492 Y504F471-V488 HydrophobicContact CB-CG2 3.78Å; L475-V488 HydrophobicContact CD1-CG1 4.36Å; L475-V488 HydrophobicContact CD1-CG2 4.04Å; L475-V488 HydrophobicContact CG-CG2 4.24Å; V484-V488 WeakPolarHBondContact O-CG2 3.38Å; V484-V488 PolarHBondContact O-N 2.8Å; H485-V488 PolarHBondContact O-N 3.25Å; Y486-V488 PolarHBondContact O-N 2.97Å; V488-K490 VanDerWaalsContact C-N 3.33Å; V488-K490 PolarHBondContact O-N 2.77Å; V488-N491 PolarHBondContact O-N 2.75Å; V488-L492 HydrophobicContact CG1-CD1 3.98Å; V488-L492 WeakPolarHBondContact O-CG 3.4Å; V488-L492 PolarHBondContact O-N 3.26Å; V488-Y504 HydrophobicContact CB-CD1 4.29Å; V488-Y504 HydrophobicContact CB-CG 4.45Å; V488-Y504 HydrophobicContact CG1-CD1 3.97Å; V488-Y504 HydrophobicContact CG1-CD2 3.92Å; V488-Y504 HydrophobicContact CG1-CE1 3.9Å; V488-Y504 HydrophobicContact CG1-CE2 3.85Å; V488-Y504 HydrophobicContact CG1-CG 3.99Å
489G97.3Very high94.6Very high0 Ų048 Ų480%026%0.262CS..Hα-helixtrans-59.5-42.4175.400000112.5H485 Y486 L492 A493 A501H485-G489 PolarHBondContact O-N 3.34Å; Y486-G489 PolarHBondContact O-N 3.07Å; G489-L492 PolarHBondContact O-N 3.25Å; G489-A493 WeakPolarHBondContact O-CB 3.33Å; G489-A493 PolarHBondContact O-N 3.27Å; G489-A501 VanDerWaalsContact O-CB 3.23Å; G489-A501 WeakPolarHBondContact O-CB 3.49Å
490K96.4Very high94.9Very high76 Ų7646 Ų4633%0.3325%0.251SS..Hα-helixtrans-59.5-51.7175-172.2-169.9169.5-155.50112Y486 N487 V488 L492 A493 D494 Y505Y486-K490 WeakPolarHBondContact O-CB 3.21Å; Y486-K490 PolarHBondContact O-N 3.23Å; N487-K490 PolarHBondContact O-N 3.36Å; V488-K490 VanDerWaalsContact C-N 3.33Å; V488-K490 PolarHBondContact O-N 2.77Å; K490-L492 PolarHBondContact O-N 3.14Å; K490-A493 PolarHBondContact O-N 3.33Å; K490-A493 VanDerWaalsContact O-N 3.11Å; K490-D494 VanDerWaalsContact O-CG 3.32Å; K490-D494 PolarHBondContact O-N 3.2Å; K490-Y505 WeakPolarHBondContact CA-OH 3.37Å; K490-Y505 PolarHBondContact N-OH 2.95Å
491N94.9Very high95.2Very high18 Ų1841.1 Ų41.110%0.09623%0.226CC..Hα-helixtrans-60-33.7178.1-78.1-7.5000113.4E467 Q468 F471 N487 V488 R495E467-N491 VanDerWaalsContact C-ND2 3.26Å; E467-N491 PolarHBondContact O-ND2 3.49Å; Q468-N491 WeakPolarHBondContact CA-ND2 3.48Å; Q468-N491 PolarHBondContact N-ND2 2.81Å; F471-N491 WeakPolarHBondContact CD2-ND2 3.32Å; N487-N491 PolarHBondContact O-N 2.84Å; N487-N491 VanDerWaalsContact O-N 3.08Å; V488-N491 PolarHBondContact O-N 2.75Å; N491-R495 WeakPolarHBondContact O-CG 3.16Å; N491-R495 PolarHBondContact O-N 2.9Å
492L96.3Very high95.5Very high38 Ų3841.5 Ų41.520%0.19923%0.228CC..Hα-helixtrans-71.7-41.7175.5-72.8165.5000111.9V488 G489 K490 R495 G496 N497 A500 A501 Y504V488-L492 HydrophobicContact CG1-CD1 3.98Å; V488-L492 WeakPolarHBondContact O-CG 3.4Å; V488-L492 PolarHBondContact O-N 3.26Å; G489-L492 PolarHBondContact O-N 3.25Å; K490-L492 PolarHBondContact O-N 3.14Å; L492-R495 PolarHBondContact O-N 3.22Å; L492-G496 PolarHBondContact O-N 3.37Å; L492-N497 HydrophobicContact CD2-CB 4.38Å; L492-N497 PolarHBondContact O-N 3.3Å; L492-A500 HydrophobicContact CD1-CB 3.87Å; L492-A500 HydrophobicContact CD2-CB 4.4Å; L492-A501 HydrophobicContact CB-CB 4.05Å; L492-Y504 HydrophobicContact CD1-CD2 3.41Å; L492-Y504 VanDerWaalsContact CD1-CD2 3.41Å; L492-Y504 HydrophobicContact CD1-CE2 3.57Å
493A95.4Very high95.7Very high24 Ų2449 Ų4920%0.19826%0.261CS..Hα-helixtrans-63.5-44.4176.800000111.6G489 K490 R495 G496 A501 Y505 I525G489-A493 WeakPolarHBondContact O-CB 3.33Å; G489-A493 PolarHBondContact O-N 3.27Å; K490-A493 PolarHBondContact O-N 3.33Å; K490-A493 VanDerWaalsContact O-N 3.11Å; A493-R495 PolarHBondContact O-N 3.29Å; A493-R495 VanDerWaalsContact O-N 3.13Å; A493-G496 PolarHBondContact O-N 2.95Å; A493-A501 HydrophobicContact CB-CB 3.85Å; A493-Y505 HydrophobicContact CB-CE2 4.5Å; A493-I525 HydrophobicContact CB-CD1 4.05Å
494D92.8Very high95.9Very high115 Ų11549.6 Ų49.662%0.61526%0.262SS*.Hα-helixtrans-62.7-21.3178.7-67.6-15.6000112.3K490K490-D494 VanDerWaalsContact O-CG 3.32Å; K490-D494 PolarHBondContact O-N 3.2Å
495R93.2Very high96.1Very high156 Ų15649.8 Ų49.859%0.58926%0.263SS*.THydrogen-bonded Turntrans-954.7174-67.1177.3-179.3-162.43.8114.1N491 L492 A493 N497N491-R495 WeakPolarHBondContact O-CG 3.16Å; N491-R495 PolarHBondContact O-N 2.9Å; L492-R495 PolarHBondContact O-N 3.22Å; A493-R495 PolarHBondContact O-N 3.29Å; A493-R495 VanDerWaalsContact O-N 3.13Å; R495-N497 VanDerWaalsContact C-N 3.34Å; R495-N497 PolarHBondContact O-N 3.38Å
496G93.9Very high96.2Very high58 Ų5853.9 Ų53.960%0.59828%0.277SS*.THydrogen-bonded Turntrans81.42.3-179.500000115.3L492 A493 T498L492-G496 PolarHBondContact O-N 3.37Å; A493-G496 PolarHBondContact O-N 2.95Å; G496-T498 VanDerWaalsContact C-N 3.27Å; G496-T498 PolarHBondContact O-N 2.93Å
497N95.6Very high96.2Very high76 Ų7654.9 Ų54.941%0.40628%0.283SS..  trans-85.869.4175.4-169-13.8000111L492 R495 T499 A500 A501L492-N497 HydrophobicContact CD2-CB 4.38Å; L492-N497 PolarHBondContact O-N 3.3Å; R495-N497 VanDerWaalsContact C-N 3.34Å; R495-N497 PolarHBondContact O-N 3.38Å; N497-T499 PolarHBondContact O-N 2.88Å; N497-A500 PolarHBondContact O-N 3.26Å; N497-A500 VanDerWaalsContact OD1-CB 3.3Å; N497-A500 WeakPolarHBondContact OD1-CB 3.46Å; N497-A500 PolarHBondContact OD1-N 2.94Å; N497-A501 WeakPolarHBondContact O-CB 3.02Å; N497-A501 PolarHBondContact O-N 3.45Å; N497-A501 VanDerWaalsContact O-N 3.09Å
498T94.9Very high96.3Very high44 Ų4454.1 Ų54.127%0.2728%0.279SS..Hα-helixtrans-65.3-35.2-175.855.20000112.6G496 A501 V502 I525G496-T498 VanDerWaalsContact C-N 3.27Å; G496-T498 PolarHBondContact O-N 2.93Å; T498-A501 WeakPolarHBondContact O-CB 3.46Å; T498-A501 PolarHBondContact O-N 3.06Å; T498-V502 WeakPolarHBondContact O-CG2 3.3Å; T498-V502 PolarHBondContact O-N 3.05Å; T498-I525 HydrophobicContact CG2-CG2 4.42Å
499T95.6Very high96.3Very high108 Ų10854.9 Ų54.966%0.66328%0.284SS*.Hα-helixtrans-61.9-46.6178.4-48.60000112.2N497N497-T499 PolarHBondContact O-N 2.88Å
500A96.4Very high96.2Very high27 Ų2762 Ų6222%0.22331%0.311CS..Hα-helixtrans-69-38.4175.900000111.4L492 N497 V502 K503 Y504L492-A500 HydrophobicContact CD1-CB 3.87Å; L492-A500 HydrophobicContact CD2-CB 4.4Å; N497-A500 PolarHBondContact O-N 3.26Å; N497-A500 VanDerWaalsContact OD1-CB 3.3Å; N497-A500 WeakPolarHBondContact OD1-CB 3.46Å; N497-A500 PolarHBondContact OD1-N 2.94Å; A500-V502 VanDerWaalsContact C-N 3.34Å; A500-V502 PolarHBondContact O-N 3.46Å; A500-K503 WeakPolarHBondContact O-CB 3.49Å; A500-K503 PolarHBondContact O-N 3.39Å; A500-Y504 VanDerWaalsContact O-CD2 3.31Å; A500-Y504 WeakPolarHBondContact O-CD2 3.37Å; A500-Y504 PolarHBondContact O-N 3.42Å
501A97.8Very high96.1Very high0 Ų060.4 Ų60.40%031%0.306CS..Hα-helixtrans-57.8-44.1176.900000112.6G489 L492 A493 N497 T498 K503 Y504 Y505 I525G489-A501 VanDerWaalsContact O-CB 3.23Å; G489-A501 WeakPolarHBondContact O-CB 3.49Å; L492-A501 HydrophobicContact CB-CB 4.05Å; A493-A501 HydrophobicContact CB-CB 3.85Å; N497-A501 WeakPolarHBondContact O-CB 3.02Å; N497-A501 PolarHBondContact O-N 3.45Å; N497-A501 VanDerWaalsContact O-N 3.09Å; T498-A501 WeakPolarHBondContact O-CB 3.46Å; T498-A501 PolarHBondContact O-N 3.06Å; A501-K503 VanDerWaalsContact C-N 3.3Å; A501-K503 PolarHBondContact O-N 3.44Å; A501-Y504 PolarHBondContact O-N 3.08Å; A501-Y504 VanDerWaalsContact O-N 3.17Å; A501-Y505 HydrophobicContact CB-CD2 4.38Å; A501-Y505 HydrophobicContact CB-CE2 4.19Å; A501-Y505 WeakPolarHBondContact O-CD2 3.34Å; A501-Y505 PolarHBondContact O-N 3.31Å; A501-I525 HydrophobicContact CB-CD1 4.15Å
502V98.1Very high96Very high9 Ų961.8 Ų61.86%0.05531%0.312CS..Hα-helixtrans-55.9-43.6176.4166.30000111.5T498 A500 Y504 Y505 R506 L522 I525T498-V502 WeakPolarHBondContact O-CG2 3.3Å; T498-V502 PolarHBondContact O-N 3.05Å; A500-V502 VanDerWaalsContact C-N 3.34Å; A500-V502 PolarHBondContact O-N 3.46Å; V502-Y504 PolarHBondContact O-N 2.89Å; V502-Y505 PolarHBondContact O-N 3.28Å; V502-R506 HydrophobicContact CG1-CG 4.38Å; V502-R506 WeakPolarHBondContact O-CB 3.39Å; V502-R506 WeakPolarHBondContact O-CG 3.42Å; V502-R506 PolarHBondContact O-N 2.91Å; V502-L522 HydrophobicContact CB-CD1 4.26Å; V502-L522 HydrophobicContact CG1-CD1 3.97Å; V502-L522 HydrophobicContact CG2-CD1 4.04Å; V502-I525 HydrophobicContact CG2-CB 4.37Å; V502-I525 HydrophobicContact CG2-CG2 3.6Å
503K97.8Very high95.9Very high156 Ų15663 Ų6368%0.67832%0.322SS*.Hα-helixtrans-58.7-47.3177.8-178.2-179176.6-1790111.6A500 A501 E507A500-K503 WeakPolarHBondContact O-CB 3.49Å; A500-K503 PolarHBondContact O-N 3.39Å; A501-K503 VanDerWaalsContact C-N 3.3Å; A501-K503 PolarHBondContact O-N 3.44Å; K503-E507 PolarHBondContact O-N 3.27Å; K503-E507 VanDerWaalsContact O-N 3.07Å
504Y98.1Very high95.8Very high66 Ų6665.9 Ų65.926%0.25933%0.334SS..Hα-helixtrans-70.5-38-179.7-77.6-73.6000112.7L475 H485 V488 L492 A500 A501 V502 E507 A508L475-Y504 HydrophobicContact CD1-CE1 3.81Å; L475-Y504 HydrophobicContact CD2-CE1 4.17Å; H485-Y504 HydrophobicContact CB-CD1 4.45Å; H485-Y504 AromaticContact ND1-CD1 3.41Å; H485-Y504 WeakPolarHBondContact ND1-CD1 3.46Å; H485-Y504 AromaticContact ND1-CE1 3.86Å; H485-Y504 WeakPolarHBondContact O-CB 3.34Å; V488-Y504 HydrophobicContact CB-CD1 4.29Å; V488-Y504 HydrophobicContact CB-CG 4.45Å; V488-Y504 HydrophobicContact CG1-CD1 3.97Å; V488-Y504 HydrophobicContact CG1-CD2 3.92Å; V488-Y504 HydrophobicContact CG1-CE1 3.9Å; V488-Y504 HydrophobicContact CG1-CE2 3.85Å; V488-Y504 HydrophobicContact CG1-CG 3.99Å; L492-Y504 HydrophobicContact CD1-CD2 3.41Å; L492-Y504 VanDerWaalsContact CD1-CD2 3.41Å; L492-Y504 HydrophobicContact CD1-CE2 3.57Å; A500-Y504 VanDerWaalsContact O-CD2 3.31Å; A500-Y504 WeakPolarHBondContact O-CD2 3.37Å; A500-Y504 PolarHBondContact O-N 3.42Å; A501-Y504 PolarHBondContact O-N 3.08Å; A501-Y504 VanDerWaalsContact O-N 3.17Å; V502-Y504 PolarHBondContact O-N 2.89Å; Y504-E507 PolarHBondContact O-N 3Å; Y504-A508 WeakPolarHBondContact O-CB 3.12Å; Y504-A508 PolarHBondContact O-N 2.9Å
505Y98.3Very high95.9Very high4 Ų461.3 Ų61.32%0.01631%0.308CS..Hα-helixtrans-66.8-40.7174.3-70.1-43.3000112.8Y486 K490 A493 A501 V502 E507 A508 V509 N521 L522 I525Y486-Y505 AromaticContact CD2-CD1 3.94Å; Y486-Y505 HydrophobicContact CD2-CD1 3.94Å; Y486-Y505 AromaticContact CD2-CE1 3.58Å; Y486-Y505 HydrophobicContact CD2-CE1 3.58Å; Y486-Y505 AromaticContact CE2-CE1 3.91Å; Y486-Y505 HydrophobicContact CE2-CE1 3.91Å; Y486-Y505 HydrophobicContact CG-CE1 4.41Å; Y486-Y505 WeakPolarHBondContact O-CE1 3.49Å; K490-Y505 WeakPolarHBondContact CA-OH 3.37Å; K490-Y505 PolarHBondContact N-OH 2.95Å; A493-Y505 HydrophobicContact CB-CE2 4.5Å; A501-Y505 HydrophobicContact CB-CD2 4.38Å; A501-Y505 HydrophobicContact CB-CE2 4.19Å; A501-Y505 WeakPolarHBondContact O-CD2 3.34Å; A501-Y505 PolarHBondContact O-N 3.31Å; V502-Y505 PolarHBondContact O-N 3.28Å; Y505-E507 VanDerWaalsContact C-N 3.28Å; Y505-E507 PolarHBondContact O-N 3.03Å; Y505-A508 WeakPolarHBondContact O-CB 3.42Å; Y505-A508 PolarHBondContact O-N 3.26Å; Y505-V509 WeakPolarHBondContact O-CG2 3.34Å; Y505-V509 PolarHBondContact O-N 3.34Å; Y505-N521 HydrophobicContact CE1-CB 4.14Å; Y505-N521 HydrophobicContact CE2-CB 3.95Å; Y505-N521 PolarHBondContact OH-ND2 3.18Å; Y505-L522 HydrophobicContact CD2-CB 4.48Å; Y505-L522 HydrophobicContact CG-CB 4.46Å; Y505-I525 HydrophobicContact CD2-CD1 4.08Å; Y505-I525 HydrophobicContact CE2-CD1 3.69Å
506R98.1Very high96.1Very high104 Ų10454.2 Ų54.239%0.39228%0.282SS..Hα-helixtrans-59.6-41.7173-78.1-175.4174.1143.2-0.2111V502 V509 R510 L522 E531 E534V502-R506 HydrophobicContact CG1-CG 4.38Å; V502-R506 WeakPolarHBondContact O-CB 3.39Å; V502-R506 WeakPolarHBondContact O-CG 3.42Å; V502-R506 PolarHBondContact O-N 2.91Å; R506-V509 PolarHBondContact O-N 3.04Å; R506-R510 WeakPolarHBondContact O-CB 3.32Å; R506-R510 PolarHBondContact O-N 3.14Å; R506-L522 HydrophobicContact CG-CD1 4.39Å; R506-L522 HydrophobicContact CG-CD2 3.77Å; R506-E531 IonicContact NH2-OE2 2.68Å; R506-E534 IonicContact CZ-OE1 3.31Å; R506-E534 IonicContact CZ-OE2 3.68Å; R506-E534 IonicContact NE-OE1 2.97Å; R506-E534 PolarHBondContact NE-OE1 3.23Å; R506-E534 IonicContact NH2-OE1 3.14Å; R506-E534 PolarHBondContact NH2-OE1 3.23Å; R506-E534 IonicContact NH2-OE2 3.92Å; R506-E534 PolarHBondContact NH2-OE2 2.75Å
507E97.5Very high96.2Very high53 Ų5355.2 Ų55.225%0.24827%0.271CS..Hα-helixtrans-66.3-40.2176.2-172.458.9-166.600112.5K503 Y504 Y505 V509 R510 L511K503-E507 PolarHBondContact O-N 3.27Å; K503-E507 VanDerWaalsContact O-N 3.07Å; Y504-E507 PolarHBondContact O-N 3Å; Y505-E507 VanDerWaalsContact C-N 3.28Å; Y505-E507 PolarHBondContact O-N 3.03Å; E507-V509 PolarHBondContact O-N 3.24Å; E507-R510 VanDerWaalsContact CD-NE 3.3Å; E507-R510 WeakPolarHBondContact O-CB 3.38Å; E507-R510 PolarHBondContact O-N 3.29Å; E507-R510 IonicContact OE1-CZ 3.87Å; E507-R510 VanDerWaalsContact OE1-CZ 3.29Å; E507-R510 IonicContact OE1-NE 3.25Å; E507-R510 PolarHBondContact OE1-NE 3.42Å; E507-R510 VanDerWaalsContact OE1-NE 3.12Å; E507-R510 IonicContact OE1-NH2 3.31Å; E507-R510 PolarHBondContact OE1-NH2 3.48Å; E507-R510 IonicContact OE2-CZ 2.54Å; E507-R510 IonicContact OE2-NE 3.57Å; E507-R510 PolarHBondContact OE2-NE 2.96Å; E507-R510 IonicContact OE2-NH2 3.94Å; E507-L511 HydrophobicContact CG-CD1 4.1Å; E507-L511 WeakPolarHBondContact O-CB 3.43Å; E507-L511 WeakPolarHBondContact O-CG 3.06Å; E507-L511 PolarHBondContact O-N 3.48Å
508A96.9Very high96.2Very high0 Ų051.6 Ų51.60%025%0.252CS..Hα-helixtrans-59.8-43.9173.600000112.1A482 H485 Y504 Y505 L511 H512 Y515 A518A482-A508 WeakPolarHBondContact CB-O 3.41Å; A482-A508 WeakPolarHBondContact O-CB 3.42Å; H485-A508 HydrophobicContact CB-CB 3.95Å; Y504-A508 WeakPolarHBondContact O-CB 3.12Å; Y504-A508 PolarHBondContact O-N 2.9Å; Y505-A508 WeakPolarHBondContact O-CB 3.42Å; Y505-A508 PolarHBondContact O-N 3.26Å; A508-L511 PolarHBondContact O-N 3.13Å; A508-H512 PolarHBondContact O-N 2.9Å; A508-Y515 HydrophobicContact CB-CD1 4.36Å; A508-A518 HydrophobicContact CB-CB 4.09Å
509V96.8Very high96.4Very high21 Ų2149.5 Ų49.513%0.12724%0.239CC..Hα-helixtrans-69.3-34.9176.1175.60000111.5Y505 R506 E507 H512 P513 A518 M519 L538Y505-V509 WeakPolarHBondContact O-CG2 3.34Å; Y505-V509 PolarHBondContact O-N 3.34Å; R506-V509 PolarHBondContact O-N 3.04Å; E507-V509 PolarHBondContact O-N 3.24Å; V509-H512 CarbonylContact O-C 3.13Å; V509-P513 WeakPolarHBondContact O-CA 3.39Å; V509-P513 VanDerWaalsContact O-N 3.12Å; V509-A518 HydrophobicContact CG2-CB 3.87Å; V509-M519 HydrophobicContact CG1-CE 4.2Å; V509-M519 HydrophobicContact CG1-CG 4.42Å; V509-M519 HydrophobicContact CG2-CG 3.93Å; V509-L538 HydrophobicContact CG1-CD2 4.38Å
510R96.3Very high96.5Very high148 Ų14845 Ų4556%0.55821%0.211SC*.Hα-helixtrans-63.6-45.1174.6-169.6-165.871.775.3-0.5111.6R506 E507R506-R510 WeakPolarHBondContact O-CB 3.32Å; R506-R510 PolarHBondContact O-N 3.14Å; E507-R510 VanDerWaalsContact CD-NE 3.3Å; E507-R510 WeakPolarHBondContact O-CB 3.38Å; E507-R510 PolarHBondContact O-N 3.29Å; E507-R510 IonicContact OE1-CZ 3.87Å; E507-R510 VanDerWaalsContact OE1-CZ 3.29Å; E507-R510 IonicContact OE1-NE 3.25Å; E507-R510 PolarHBondContact OE1-NE 3.42Å; E507-R510 VanDerWaalsContact OE1-NE 3.12Å; E507-R510 IonicContact OE1-NH2 3.31Å; E507-R510 PolarHBondContact OE1-NH2 3.48Å; E507-R510 IonicContact OE2-CZ 2.54Å; E507-R510 IonicContact OE2-NE 3.57Å; E507-R510 PolarHBondContact OE2-NE 2.96Å; E507-R510 IonicContact OE2-NH2 3.94Å
511L93.3Very high96.6Very high43 Ų4345.7 Ų45.723%0.22521%0.21CC..Hα-helixtrans-71.6-38.7179.7-71.8168.7000112.2L480 A482 H485 E507 A508L480-L511 HydrophobicContact CB-CD2 4.33Å; L480-L511 HydrophobicContact CD2-CD2 3.99Å; A482-L511 HydrophobicContact CB-CB 3.92Å; H485-L511 WeakPolarHBondContact CD2-CD1 3.34Å; E507-L511 HydrophobicContact CG-CD1 4.1Å; E507-L511 WeakPolarHBondContact O-CB 3.43Å; E507-L511 WeakPolarHBondContact O-CG 3.06Å; E507-L511 PolarHBondContact O-N 3.48Å; A508-L511 PolarHBondContact O-N 3.13Å
512H93.1Very high96.6Very high48 Ų4845.8 Ų45.822%0.22221%0.211CC..  trans-129.891.1175-169.258.6000110.9M340 A482 A508 V509 N514 Y515M340-H512 HydrophobicContact SD-CB 4.39Å; A482-H512 HydrophobicContact CB-CB 3.55Å; A508-H512 PolarHBondContact O-N 2.9Å; V509-H512 CarbonylContact O-C 3.13Å; H512-N514 PolarHBondContact O-N 2.88Å; H512-Y515 PolarHBondContact CD2-N 2.98Å; H512-Y515 WeakPolarHBondContact O-CB 3.5Å; H512-Y515 PolarHBondContact O-N 3.46Å
513P94.1Very high96.6Very high64 Ų6445.3 Ų45.342%0.41621%0.208SC..THydrogen-bonded Turntrans-63.1-5.2-175.3-27.236.5000116.5V509 M519 K541V509-P513 WeakPolarHBondContact O-CA 3.39Å; V509-P513 VanDerWaalsContact O-N 3.12Å; P513-M519 WeakPolarHBondContact O-CE 3.46Å; P513-K541 WeakPolarHBondContact O-CE 3.37Å; P513-K541 PolarHBondContact O-NZ 2.96Å
514N93.9Very high96.5Very high84 Ų8440 Ų4045%0.44919%0.187SC..THydrogen-bonded Turntrans-111.713.7176.8-69-10.8000112.1H512 V516 V545H512-N514 PolarHBondContact O-N 2.88Å; N514-V516 WeakPolarHBondContact O-CG1 3.43Å; N514-V516 PolarHBondContact O-N 2.93Å; N514-V545 HydrophobicContact CB-CG1 4Å; N514-V545 HydrophobicContact CB-CG2 4.38Å
515Y94.9Very high96.5Very high18 Ų1837.4 Ų37.47%0.07118%0.178CC..  trans-75.783.7-178.1-158.1173.8000112.6M340 A482 K483 Y486 A508 H512 H517 A518 M519M340-Y515 HydrophobicContact CE-CD1 4.48Å; M340-Y515 HydrophobicContact CE-CD2 4.19Å; M340-Y515 HydrophobicContact CE-CE1 4.18Å; M340-Y515 HydrophobicContact CE-CE2 3.87Å; M340-Y515 HydrophobicContact CE-CG 4.49Å; M340-Y515 HydrophobicContact SD-CE1 4.48Å; A482-Y515 HydrophobicContact CB-CD1 4.08Å; A482-Y515 HydrophobicContact CB-CE1 4.4Å; K483-Y515 HydrophobicContact CB-CE1 4.49Å; Y486-Y515 HydrophobicContact CD1-CE1 4.42Å; Y486-Y515 AromaticContact CD1-CZ 4Å; Y486-Y515 VanDerWaalsContact CD1-OH 3.26Å; Y486-Y515 WeakPolarHBondContact CD1-OH 3.4Å; Y486-Y515 HydrophobicContact CD2-CE1 4.45Å; Y486-Y515 AromaticContact CG-CE1 3.89Å; Y486-Y515 HydrophobicContact CG-CE1 3.89Å; Y486-Y515 AromaticContact CG-CZ 3.84Å; A508-Y515 HydrophobicContact CB-CD1 4.36Å; H512-Y515 PolarHBondContact CD2-N 2.98Å; H512-Y515 WeakPolarHBondContact O-CB 3.5Å; H512-Y515 PolarHBondContact O-N 3.46Å; Y515-H517 VanDerWaalsContact C-N 3.3Å; Y515-H517 HydrophobicContact CD2-CB 4.24Å; Y515-H517 HydrophobicContact CE2-CB 3.91Å; Y515-H517 PolarHBondContact O-N 2.86Å; Y515-A518 HydrophobicContact CD1-CB 3.83Å; Y515-A518 HydrophobicContact CD2-CB 4.48Å; Y515-A518 HydrophobicContact CE1-CB 4.39Å; Y515-A518 HydrophobicContact CG-CB 3.88Å; Y515-A518 PolarHBondContact O-N 3.3Å; Y515-A518 VanDerWaalsContact O-N 3.11Å; Y515-M519 WeakPolarHBondContact O-CG 3.32Å; Y515-M519 PolarHBondContact O-N 2.77Å
516V95.9Very high96.5Very high7 Ų737.2 Ų37.24%0.04218%0.177CC..Hα-helixtrans-59.9-33.7-172.3-57.10000114.3N514 M519 N520 A542 V545 Q546 F549N514-V516 WeakPolarHBondContact O-CG1 3.43Å; N514-V516 PolarHBondContact O-N 2.93Å; V516-M519 PolarHBondContact O-N 2.94Å; V516-N520 WeakPolarHBondContact O-CB 3.18Å; V516-N520 PolarHBondContact O-N 3.5Å; V516-A542 HydrophobicContact CB-CB 4.18Å; V516-A542 HydrophobicContact CG1-CB 4.37Å; V516-A542 WeakPolarHBondContact CG1-O 3.32Å; V516-V545 HydrophobicContact CG1-CB 3.77Å; V516-V545 HydrophobicContact CG1-CG1 3.63Å; V516-Q546 HydrophobicContact CB-CB 4.49Å; V516-Q546 HydrophobicContact CG1-CB 3.91Å; V516-Q546 HydrophobicContact CG2-CB 4.22Å; V516-Q546 VanDerWaalsContact CG2-OE1 3.28Å; V516-F549 HydrophobicContact CB-CD1 4.1Å; V516-F549 HydrophobicContact CB-CE1 4.39Å; V516-F549 HydrophobicContact CG2-CD1 3.96Å; V516-F549 HydrophobicContact CG2-CE1 4.23Å
517H95.9Very high96.4Very high80 Ų8034.5 Ų34.537%0.3717%0.168SC..Hα-helixtrans-68.1-40177.4-61.8-51.5000112.3Y486 Y515 N520 N521 F549Y486-H517 HydrophobicContact CE2-CB 4.05Å; Y515-H517 VanDerWaalsContact C-N 3.3Å; Y515-H517 HydrophobicContact CD2-CB 4.24Å; Y515-H517 HydrophobicContact CE2-CB 3.91Å; Y515-H517 PolarHBondContact O-N 2.86Å; H517-N520 PolarHBondContact O-N 3.32Å; H517-N521 PolarHBondContact O-N 3.08Å; H517-N521 VanDerWaalsContact O-N 3.09Å; H517-F549 AromaticContact ND1-CE1 3.8Å; H517-F549 AromaticContact ND1-CZ 3.54Å
518A96.9Very high96.2Very high0 Ų037.8 Ų37.80%018%0.183CC..Hα-helixtrans-66.7-42.2174.800000111.3Y486 A508 V509 Y515 N520 N521 L522Y486-A518 HydrophobicContact CD2-CB 3.77Å; A508-A518 HydrophobicContact CB-CB 4.09Å; V509-A518 HydrophobicContact CG2-CB 3.87Å; Y515-A518 HydrophobicContact CD1-CB 3.83Å; Y515-A518 HydrophobicContact CD2-CB 4.48Å; Y515-A518 HydrophobicContact CE1-CB 4.39Å; Y515-A518 HydrophobicContact CG-CB 3.88Å; Y515-A518 PolarHBondContact O-N 3.3Å; Y515-A518 VanDerWaalsContact O-N 3.11Å; A518-N520 PolarHBondContact O-N 2.95Å; A518-N521 PolarHBondContact O-N 3.49Å; A518-L522 WeakPolarHBondContact O-CB 3.45Å; A518-L522 PolarHBondContact O-N 2.86Å
519M98.4Very high96.1Very high0 Ų041.2 Ų41.20%020%0.199CC..Hα-helixtrans-60.1-44.9174.7-66.8174.9-177.100112.3V509 P513 Y515 V516 G523 L538 K541 A542V509-M519 HydrophobicContact CG1-CE 4.2Å; V509-M519 HydrophobicContact CG1-CG 4.42Å; V509-M519 HydrophobicContact CG2-CG 3.93Å; P513-M519 WeakPolarHBondContact O-CE 3.46Å; Y515-M519 WeakPolarHBondContact O-CG 3.32Å; Y515-M519 PolarHBondContact O-N 2.77Å; V516-M519 PolarHBondContact O-N 2.94Å; M519-G523 PolarHBondContact O-N 3.12Å; M519-L538 HydrophobicContact CB-CB 4.4Å; M519-L538 HydrophobicContact CG-CD2 4.21Å; M519-K541 HydrophobicContact CE-CD 3.67Å; M519-K541 HydrophobicContact CE-CG 4.03Å; M519-K541 HydrophobicContact SD-CB 4.24Å; M519-K541 HydrophobicContact SD-CD 4.35Å; M519-K541 HydrophobicContact SD-CG 4.19Å; M519-A542 HydrophobicContact CB-CB 4.03Å; M519-A542 HydrophobicContact SD-CB 4.01Å
520N98.1Very high96.1Very high14 Ų1446.1 Ų46.18%0.07523%0.225CC..Hα-helixtrans-62.8-46.8179.717582.3000112V516 H517 A518 G523 N524 L539 F549 A552 N555V516-N520 WeakPolarHBondContact O-CB 3.18Å; V516-N520 PolarHBondContact O-N 3.5Å; H517-N520 PolarHBondContact O-N 3.32Å; A518-N520 PolarHBondContact O-N 2.95Å; N520-G523 PolarHBondContact O-N 3.37Å; N520-N524 PolarHBondContact O-N 3.25Å; N520-L539 HydrophobicContact CB-CD2 4.45Å; N520-F549 HydrophobicContact CB-CE1 3.68Å; N520-F549 HydrophobicContact CB-CZ 4.02Å; N520-A552 WeakPolarHBondContact OD1-CA 3.28Å; N520-N555 PolarHBondContact OD1-ND2 3.35Å
521N98.1Very high96.1Very high40 Ų4043 Ų4321%0.21422%0.217CC..Hα-helixtrans-69.5-39.6-179.7-69.12.5000111.7Y486 Y505 H517 A518 N524 I525Y486-N521 WeakPolarHBondContact CE2-ND2 3.33Å; Y486-N521 PolarHBondContact OH-ND2 2.95Å; Y505-N521 HydrophobicContact CE1-CB 4.14Å; Y505-N521 HydrophobicContact CE2-CB 3.95Å; Y505-N521 PolarHBondContact OH-ND2 3.18Å; H517-N521 PolarHBondContact O-N 3.08Å; H517-N521 VanDerWaalsContact O-N 3.09Å; A518-N521 PolarHBondContact O-N 3.49Å; N521-N524 PolarHBondContact O-N 3.35Å; N521-I525 PolarHBondContact O-N 2.9Å
522L98.3Very high96.3Very high2 Ų242 Ų421%0.0121%0.211CC..Hα-helixtrans-61.6-48.2173.2-18054.6000111.2V502 Y505 R506 A518 N524 I525 L526 L538V502-L522 HydrophobicContact CB-CD1 4.26Å; V502-L522 HydrophobicContact CG1-CD1 3.97Å; V502-L522 HydrophobicContact CG2-CD1 4.04Å; Y505-L522 HydrophobicContact CD2-CB 4.48Å; Y505-L522 HydrophobicContact CG-CB 4.46Å; R506-L522 HydrophobicContact CG-CD1 4.39Å; R506-L522 HydrophobicContact CG-CD2 3.77Å; A518-L522 WeakPolarHBondContact O-CB 3.45Å; A518-L522 PolarHBondContact O-N 2.86Å; L522-N524 VanDerWaalsContact C-N 3.27Å; L522-N524 PolarHBondContact O-N 3.32Å; L522-I525 PolarHBondContact O-N 3.02Å; L522-I525 VanDerWaalsContact O-N 3.15Å; L522-L526 HydrophobicContact CD1-CD1 3.97Å; L522-L526 HydrophobicContact CD1-CD2 4.47Å; L522-L526 HydrophobicContact CD1-CG 3.98Å; L522-L526 HydrophobicContact CG-CD1 3.82Å; L522-L526 HydrophobicContact CG-CG 4.29Å; L522-L526 WeakPolarHBondContact O-CG 3.27Å; L522-L526 PolarHBondContact O-N 3.28Å; L522-L538 HydrophobicContact CB-CD1 4.37Å; L522-L538 HydrophobicContact CD2-CD1 3.58Å; L522-L538 HydrophobicContact CG-CD1 3.72Å
523G97.7Very high96.5Very high0 Ų043.3 Ų43.30%023%0.226CC..Hα-helixtrans-59-37.3177.600000112.7M519 N520 K527 A535M519-G523 PolarHBondContact O-N 3.12Å; N520-G523 PolarHBondContact O-N 3.37Å; G523-K527 VanDerWaalsContact O-CB 3.32Å; G523-K527 WeakPolarHBondContact O-CB 3.41Å; G523-K527 PolarHBondContact O-N 2.61Å; G523-A535 WeakPolarHBondContact O-CB 3.42Å
524N96.6Very high96.7Very high45 Ų4543 Ų4324%0.24122%0.219CC..Hα-helixtrans-64.9-42.8175.3-171.658000112.7N520 N521 L522 K527 E528N520-N524 PolarHBondContact O-N 3.25Å; N521-N524 PolarHBondContact O-N 3.35Å; L522-N524 VanDerWaalsContact C-N 3.27Å; L522-N524 PolarHBondContact O-N 3.32Å; N524-K527 WeakPolarHBondContact O-CB 3.48Å; N524-K527 PolarHBondContact O-N 3.48Å; N524-K527 PolarHBondContact OD1-NZ 3.06Å; N524-E528 PolarHBondContact ND2-OE1 3.49Å; N524-E528 VanDerWaalsContact ND2-OE1 3.12Å; N524-E528 WeakPolarHBondContact O-CG 3.43Å; N524-E528 PolarHBondContact O-N 3.18Å
525I97.2Very high96.9Very high10 Ų1039 Ų395%0.05120%0.198CC..Hα-helixtrans-67.5-44.3177.3-65.2174.4000110.8A493 T498 A501 V502 Y505 N521 L522 K527 E528 Q529A493-I525 HydrophobicContact CB-CD1 4.05Å; T498-I525 HydrophobicContact CG2-CG2 4.42Å; A501-I525 HydrophobicContact CB-CD1 4.15Å; V502-I525 HydrophobicContact CG2-CB 4.37Å; V502-I525 HydrophobicContact CG2-CG2 3.6Å; Y505-I525 HydrophobicContact CD2-CD1 4.08Å; Y505-I525 HydrophobicContact CE2-CD1 3.69Å; N521-I525 PolarHBondContact O-N 2.9Å; L522-I525 PolarHBondContact O-N 3.02Å; L522-I525 VanDerWaalsContact O-N 3.15Å; I525-K527 VanDerWaalsContact C-N 3.28Å; I525-K527 PolarHBondContact O-N 3.39Å; I525-E528 WeakPolarHBondContact O-CB 3.46Å; I525-E528 PolarHBondContact O-N 3.12Å; I525-E528 VanDerWaalsContact O-N 3.07Å; I525-Q529 HydrophobicContact CG2-CG 4.46Å; I525-Q529 WeakPolarHBondContact O-CG 3.25Å; I525-Q529 PolarHBondContact O-N 3.18Å
526L97.6Very high97.1Very high0 Ų039.5 Ų39.50%020%0.201CC..Hα-helixtrans-61.8-38.2178.2-69.7173.1000111.7L522 E528 Q529 N530 E531 E534 A535 L538L522-L526 HydrophobicContact CD1-CD1 3.97Å; L522-L526 HydrophobicContact CD1-CD2 4.47Å; L522-L526 HydrophobicContact CD1-CG 3.98Å; L522-L526 HydrophobicContact CG-CD1 3.82Å; L522-L526 HydrophobicContact CG-CG 4.29Å; L522-L526 WeakPolarHBondContact O-CG 3.27Å; L522-L526 PolarHBondContact O-N 3.28Å; L526-E528 PolarHBondContact O-N 2.69Å; L526-Q529 CarbonylContact O-C 3.41Å; L526-Q529 PolarHBondContact O-N 3.38Å; L526-Q529 VanDerWaalsContact O-N 3.16Å; L526-N530 PolarHBondContact O-N 3.09Å; L526-N530 VanDerWaalsContact O-N 3.1Å; L526-E531 HydrophobicContact CB-CB 4.12Å; L526-E531 HydrophobicContact CD2-CB 4.02Å; L526-E531 HydrophobicContact CD2-CG 4.46Å; L526-E531 PolarHBondContact O-N 2.96Å; L526-E534 HydrophobicContact CD1-CB 4.05Å; L526-E534 HydrophobicContact CD1-CG 3.7Å; L526-A535 HydrophobicContact CB-CB 4Å; L526-L538 HydrophobicContact CD1-CD1 3.66Å
527K95.9Very high97.2Very high47 Ų4745.8 Ų45.820%0.20423%0.229CC..Hα-helixtrans-58.2-45.8171.3175.6-144.371.2-169.60111.7G523 N524 I525 Q529 N530 L532 I558 V559G523-K527 VanDerWaalsContact O-CB 3.32Å; G523-K527 WeakPolarHBondContact O-CB 3.41Å; G523-K527 PolarHBondContact O-N 2.61Å; N524-K527 WeakPolarHBondContact O-CB 3.48Å; N524-K527 PolarHBondContact O-N 3.48Å; N524-K527 PolarHBondContact OD1-NZ 3.06Å; I525-K527 VanDerWaalsContact C-N 3.28Å; I525-K527 PolarHBondContact O-N 3.39Å; K527-Q529 VanDerWaalsContact C-N 3.25Å; K527-Q529 PolarHBondContact O-N 3.2Å; K527-N530 PolarHBondContact O-N 3Å; K527-N530 VanDerWaalsContact O-N 3.08Å; K527-L532 HydrophobicContact CG-CD2 4.21Å; K527-I558 HydrophobicContact CD-CG2 3.8Å; K527-V559 HydrophobicContact CB-CG2 3.94Å; K527-V559 HydrophobicContact CD-CG2 4.4Å; K527-V559 HydrophobicContact CG-CG2 3.91Å
528E94.6Very high97.3Very high123 Ų12343 Ų4358%0.57522%0.217SC*.Hα-helixtrans-65.6-28.9177-70.9166.3-164.700112.6N524 I525 L526 N530N524-E528 PolarHBondContact ND2-OE1 3.49Å; N524-E528 VanDerWaalsContact ND2-OE1 3.12Å; N524-E528 WeakPolarHBondContact O-CG 3.43Å; N524-E528 PolarHBondContact O-N 3.18Å; I525-E528 WeakPolarHBondContact O-CB 3.46Å; I525-E528 PolarHBondContact O-N 3.12Å; I525-E528 VanDerWaalsContact O-N 3.07Å; L526-E528 PolarHBondContact O-N 2.69Å; E528-N530 VanDerWaalsContact C-N 3.27Å
529Q95.3Very high97.4Very high71 Ų7143 Ų4333%0.33222%0.217SC..THydrogen-bonded Turntrans-83.53.1173.3-68.1174.7-1700113.7I525 L526 K527 E531I525-Q529 HydrophobicContact CG2-CG 4.46Å; I525-Q529 WeakPolarHBondContact O-CG 3.25Å; I525-Q529 PolarHBondContact O-N 3.18Å; L526-Q529 CarbonylContact O-C 3.41Å; L526-Q529 PolarHBondContact O-N 3.38Å; L526-Q529 VanDerWaalsContact O-N 3.16Å; K527-Q529 VanDerWaalsContact C-N 3.25Å; K527-Q529 PolarHBondContact O-N 3.2Å; Q529-E531 HydrophobicContact CB-CG 4.47Å; Q529-E531 PolarHBondContact O-N 3.46Å
530N95.3Very high97.4Very high124 Ų12445.1 Ų45.166%0.66323%0.232SC*.THydrogen-bonded Turntrans62.818.7-176-159.954.2000114.7L526 K527 E528 L532L526-N530 PolarHBondContact O-N 3.09Å; L526-N530 VanDerWaalsContact O-N 3.1Å; K527-N530 PolarHBondContact O-N 3Å; K527-N530 VanDerWaalsContact O-N 3.08Å; E528-N530 VanDerWaalsContact C-N 3.27Å; N530-L532 PolarHBondContact O-N 3.45Å
531E97.2Very high97.4Very high83 Ų8348.6 Ų48.639%0.38825%0.247SC..  trans-84.258.6171.7-66.9-173.1-125.900110.5R506 L526 Q529 S533 A535R506-E531 IonicContact NH2-OE2 2.68Å; L526-E531 HydrophobicContact CB-CB 4.12Å; L526-E531 HydrophobicContact CD2-CB 4.02Å; L526-E531 HydrophobicContact CD2-CG 4.46Å; L526-E531 PolarHBondContact O-N 2.96Å; Q529-E531 HydrophobicContact CB-CG 4.47Å; Q529-E531 PolarHBondContact O-N 3.46Å; E531-S533 PolarHBondContact O-N 3.47Å; E531-A535 PolarHBondContact O-N 3.08Å
532L97.6Very high97.3Very high22 Ų2246.7 Ų46.712%0.11524%0.236CC..Hα-helixtrans-64.4-33.9-167.4-60.5178.5000114.1K527 N530 A535 E536 V559 L563K527-L532 HydrophobicContact CG-CD2 4.21Å; N530-L532 PolarHBondContact O-N 3.45Å; L532-A535 PolarHBondContact O-N 3.1Å; L532-E536 WeakPolarHBondContact O-CB 3.39Å; L532-E536 PolarHBondContact O-N 3.3Å; L532-V559 HydrophobicContact CB-CG1 4.34Å; L532-V559 HydrophobicContact CD2-CG1 4.47Å; L532-V559 VanDerWaalsContact O-CG1 3.3Å; L532-V559 WeakPolarHBondContact O-CG1 3.36Å; L532-L563 HydrophobicContact CB-CD1 4.32Å; L532-L563 HydrophobicContact CB-CD2 3.67Å; L532-L563 HydrophobicContact CB-CG 3.94Å; L532-L563 HydrophobicContact CD1-CD2 3.98Å; L532-L563 HydrophobicContact CD1-CG 4.23Å
533S97.4Very high97.3Very high76 Ų7647 Ų4753%0.53124%0.238SC..Hα-helixtrans-68-44.3-177.8-570000113E531 E536 Q537E531-S533 PolarHBondContact O-N 3.47Å; S533-E536 PolarHBondContact O-N 3.41Å; S533-Q537 WeakPolarHBondContact O-CG 3.39Å; S533-Q537 PolarHBondContact O-N 3.22Å
534E97.5Very high97.3Very high57 Ų5750.7 Ų50.727%0.26627%0.269SS..Hα-helixtrans-68-40175.9-174-176.4169.700110.2R506 L526 E536 Q537 L538R506-E534 IonicContact CZ-OE1 3.31Å; R506-E534 IonicContact CZ-OE2 3.68Å; R506-E534 IonicContact NE-OE1 2.97Å; R506-E534 PolarHBondContact NE-OE1 3.23Å; R506-E534 IonicContact NH2-OE1 3.14Å; R506-E534 PolarHBondContact NH2-OE1 3.23Å; R506-E534 IonicContact NH2-OE2 3.92Å; R506-E534 PolarHBondContact NH2-OE2 2.75Å; L526-E534 HydrophobicContact CD1-CB 4.05Å; L526-E534 HydrophobicContact CD1-CG 3.7Å; E534-E536 VanDerWaalsContact C-N 3.35Å; E534-E536 PolarHBondContact O-N 3.16Å; E534-Q537 PolarHBondContact O-N 3.07Å; E534-L538 HydrophobicContact CG-CD1 3.96Å; E534-L538 HydrophobicContact CG-CG 4.45Å; E534-L538 WeakPolarHBondContact O-CG 3.46Å; E534-L538 PolarHBondContact O-N 3.38Å
535A98.4Very high97.3Very high0 Ų051.5 Ų51.50%028%0.275CS..Hα-helixtrans-58.1-45.4175.900000112.1G523 L526 E531 L532 L538 L539 V559G523-A535 WeakPolarHBondContact O-CB 3.42Å; L526-A535 HydrophobicContact CB-CB 4Å; E531-A535 PolarHBondContact O-N 3.08Å; L532-A535 PolarHBondContact O-N 3.1Å; A535-L538 PolarHBondContact O-N 2.95Å; A535-L539 WeakPolarHBondContact O-CB 3.49Å; A535-L539 WeakPolarHBondContact O-CD1 3.5Å; A535-L539 VanDerWaalsContact O-CG 3.27Å; A535-L539 WeakPolarHBondContact O-CG 3.35Å; A535-L539 PolarHBondContact O-N 3.15Å; A535-V559 HydrophobicContact CB-CG1 4.21Å; A535-V559 HydrophobicContact CB-CG2 4.02Å
536E98.4Very high97.2Very high29 Ų2954.1 Ų54.114%0.13629%0.287CS..Hα-helixtrans-61.4-44.7177-173.2-176.3-154.600111.5L532 S533 E534 L539 S540 L556 V559 Q560 L563 K565L532-E536 WeakPolarHBondContact O-CB 3.39Å; L532-E536 PolarHBondContact O-N 3.3Å; S533-E536 PolarHBondContact O-N 3.41Å; E534-E536 VanDerWaalsContact C-N 3.35Å; E534-E536 PolarHBondContact O-N 3.16Å; E536-L539 PolarHBondContact O-N 3.32Å; E536-S540 WeakPolarHBondContact O-CB 3.32Å; E536-S540 PolarHBondContact O-N 3.49Å; E536-S540 PolarHBondContact O-OG 2.91Å; E536-L556 HydrophobicContact CG-CD1 3.98Å; E536-V559 HydrophobicContact CB-CG1 3.85Å; E536-Q560 HydrophobicContact CG-CG 4.46Å; E536-L563 HydrophobicContact CB-CD1 4.15Å; E536-L563 HydrophobicContact CG-CD1 4.42Å; E536-L563 WeakPolarHBondContact OE2-CD1 3.13Å; E536-K565 VanDerWaalsContact OE1-CD 3.27Å; E536-K565 WeakPolarHBondContact OE1-CD 3.37Å; E536-K565 IonicContact OE1-NZ 2.68Å; E536-K565 PolarHBondContact OE1-NZ 2.96Å; E536-K565 IonicContact OE2-NZ 2.74Å; E536-K565 PolarHBondContact OE2-NZ 3.48Å
537Q98.1Very high97.2Very high138 Ų13856.9 Ų56.965%0.64531%0.305SS*.Hα-helixtrans-61.5-46.9179-71.6175.411.300111.9S533 E534 K541S533-Q537 WeakPolarHBondContact O-CG 3.39Å; S533-Q537 PolarHBondContact O-N 3.22Å; E534-Q537 PolarHBondContact O-N 3.07Å; Q537-K541 WeakPolarHBondContact O-CB 3.49Å; Q537-K541 PolarHBondContact O-N 2.85Å
538L98.3Very high97.1Very high23 Ų2359.2 Ų59.212%0.1232%0.32CS..Hα-helixtrans-64.2-45.3179.4-72.7166.3000111.9V509 M519 L522 L526 E534 A535 K541 A542V509-L538 HydrophobicContact CG1-CD2 4.38Å; M519-L538 HydrophobicContact CB-CB 4.4Å; M519-L538 HydrophobicContact CG-CD2 4.21Å; L522-L538 HydrophobicContact CB-CD1 4.37Å; L522-L538 HydrophobicContact CD2-CD1 3.58Å; L522-L538 HydrophobicContact CG-CD1 3.72Å; L526-L538 HydrophobicContact CD1-CD1 3.66Å; E534-L538 HydrophobicContact CG-CD1 3.96Å; E534-L538 HydrophobicContact CG-CG 4.45Å; E534-L538 WeakPolarHBondContact O-CG 3.46Å; E534-L538 PolarHBondContact O-N 3.38Å; A535-L538 PolarHBondContact O-N 2.95Å; L538-K541 PolarHBondContact O-N 2.9Å; L538-A542 WeakPolarHBondContact O-CB 3.19Å; L538-A542 PolarHBondContact O-N 3.06Å
539L98.5Very high97.2Very high0 Ų054.8 Ų54.80%030%0.299CS..Hα-helixtrans-69.9-38.6-179.4-70.9165.1000111.9N520 A535 E536 K541 A542 V543 A552 N555 L556 V559N520-L539 HydrophobicContact CB-CD2 4.45Å; A535-L539 WeakPolarHBondContact O-CB 3.49Å; A535-L539 WeakPolarHBondContact O-CD1 3.5Å; A535-L539 VanDerWaalsContact O-CG 3.27Å; A535-L539 WeakPolarHBondContact O-CG 3.35Å; A535-L539 PolarHBondContact O-N 3.15Å; E536-L539 PolarHBondContact O-N 3.32Å; L539-K541 VanDerWaalsContact C-N 3.31Å; L539-K541 PolarHBondContact O-N 2.81Å; L539-A542 WeakPolarHBondContact O-CB 3.49Å; L539-A542 PolarHBondContact O-N 2.91Å; L539-V543 WeakPolarHBondContact O-CG2 3.12Å; L539-V543 PolarHBondContact O-N 2.91Å; L539-A552 HydrophobicContact CD2-CB 4.46Å; L539-N555 HydrophobicContact CD1-CB 3.98Å; L539-N555 HydrophobicContact CD2-CB 3.84Å; L539-L556 HydrophobicContact CB-CB 4Å; L539-L556 HydrophobicContact CB-CD1 3.92Å; L539-L556 HydrophobicContact CB-CG 4.48Å; L539-V559 HydrophobicContact CD1-CG2 3.82Å
540S98.4Very high97.2Very high44 Ų4451.9 Ų51.931%0.30829%0.287SS..Hα-helixtrans-61-41.8173.3-60.20000111.2E536 V543 A544 L556E536-S540 WeakPolarHBondContact O-CB 3.32Å; E536-S540 PolarHBondContact O-N 3.49Å; E536-S540 PolarHBondContact O-OG 2.91Å; S540-V543 VanDerWaalsContact O-CG2 3.25Å; S540-V543 WeakPolarHBondContact O-CG2 3.28Å; S540-A544 WeakPolarHBondContact O-CB 3.34Å; S540-A544 PolarHBondContact O-N 2.97Å; S540-A544 VanDerWaalsContact O-N 3.09Å; S540-L556 WeakPolarHBondContact OG-CD1 3.47Å
541K98.1Very high97.3Very high87 Ų8747 Ų4738%0.37826%0.264SS..Hα-helixtrans-65.5-41.6173.7-170.8175.9-176.8-170.40111.8P513 M519 Q537 L538 L539 V543 A544 V545P513-K541 WeakPolarHBondContact O-CE 3.37Å; P513-K541 PolarHBondContact O-NZ 2.96Å; M519-K541 HydrophobicContact CE-CD 3.67Å; M519-K541 HydrophobicContact CE-CG 4.03Å; M519-K541 HydrophobicContact SD-CB 4.24Å; M519-K541 HydrophobicContact SD-CD 4.35Å; M519-K541 HydrophobicContact SD-CG 4.19Å; Q537-K541 WeakPolarHBondContact O-CB 3.49Å; Q537-K541 PolarHBondContact O-N 2.85Å; L538-K541 PolarHBondContact O-N 2.9Å; L539-K541 VanDerWaalsContact C-N 3.31Å; L539-K541 PolarHBondContact O-N 2.81Å; K541-V543 PolarHBondContact O-N 3.4Å; K541-A544 PolarHBondContact O-N 3.47Å; K541-V545 HydrophobicContact CG-CG2 4.41Å; K541-V545 WeakPolarHBondContact O-CG2 3.43Å; K541-V545 PolarHBondContact O-N 3.44Å
542A97.9Very high97.4Very high0 Ų043.1 Ų43.10%025%0.246CC..Hα-helixtrans-59.6-44.9179.700000112V516 M519 L538 L539 V545 Q546 A552V516-A542 HydrophobicContact CB-CB 4.18Å; V516-A542 HydrophobicContact CG1-CB 4.37Å; V516-A542 WeakPolarHBondContact CG1-O 3.32Å; M519-A542 HydrophobicContact CB-CB 4.03Å; M519-A542 HydrophobicContact SD-CB 4.01Å; L538-A542 WeakPolarHBondContact O-CB 3.19Å; L538-A542 PolarHBondContact O-N 3.06Å; L539-A542 WeakPolarHBondContact O-CB 3.49Å; L539-A542 PolarHBondContact O-N 2.91Å; A542-V545 PolarHBondContact O-N 3.11Å; A542-Q546 PolarHBondContact O-N 3.21Å; A542-A552 HydrophobicContact CB-CB 4.22Å
543V97.9Very high97.4Very high8 Ų843.8 Ų43.85%0.04825%0.247CC..Hα-helixtrans-74.4-26.1178.5-59.60000113.3L539 S540 K541 Q546 P547 A552 W553 L556L539-V543 WeakPolarHBondContact O-CG2 3.12Å; L539-V543 PolarHBondContact O-N 2.91Å; S540-V543 VanDerWaalsContact O-CG2 3.25Å; S540-V543 WeakPolarHBondContact O-CG2 3.28Å; K541-V543 PolarHBondContact O-N 3.4Å; V543-Q546 CarbonylContact O-C 3.2Å; V543-P547 WeakPolarHBondContact O-CA 3.16Å; V543-A552 HydrophobicContact CG1-CB 3.74Å; V543-W553 HydrophobicContact CB-CD2 3.86Å; V543-W553 HydrophobicContact CB-CE3 4.24Å; V543-W553 HydrophobicContact CB-CG 4.4Å; V543-W553 HydrophobicContact CB-CH2 4.06Å; V543-W553 HydrophobicContact CB-CZ2 3.64Å; V543-W553 HydrophobicContact CB-CZ3 4.34Å; V543-W553 HydrophobicContact CG1-CB 4.38Å; V543-W553 HydrophobicContact CG1-CD2 3.57Å; V543-W553 HydrophobicContact CG1-CE3 4.02Å; V543-W553 HydrophobicContact CG1-CG 3.72Å; V543-W553 HydrophobicContact CG1-CZ2 4.33Å; V543-W553 HydrophobicContact CG2-CD2 4.27Å; V543-W553 HydrophobicContact CG2-CE3 4.15Å; V543-W553 HydrophobicContact CG2-CH2 3.69Å; V543-W553 HydrophobicContact CG2-CZ2 3.81Å; V543-W553 HydrophobicContact CG2-CZ3 3.87Å; V543-L556 HydrophobicContact CG2-CD2 3.92Å
544A97.9Very high97.5Very high78 Ų7841 Ų4165%0.64523%0.226SC*.Hα-helixtrans-69.9-38.5171.800000112.1S540 K541S540-A544 WeakPolarHBondContact O-CB 3.34Å; S540-A544 PolarHBondContact O-N 2.97Å; S540-A544 VanDerWaalsContact O-N 3.09Å; K541-A544 PolarHBondContact O-N 3.47Å
545V95.8Very high97.5Very high62 Ų6239.2 Ų39.238%0.37622%0.218SC..Hα-helixtrans-74-45176.9172.20000111.3N514 V516 K541 A542N514-V545 HydrophobicContact CB-CG1 4Å; N514-V545 HydrophobicContact CB-CG2 4.38Å; V516-V545 HydrophobicContact CG1-CB 3.77Å; V516-V545 HydrophobicContact CG1-CG1 3.63Å; K541-V545 HydrophobicContact CG-CG2 4.41Å; K541-V545 WeakPolarHBondContact O-CG2 3.43Å; K541-V545 PolarHBondContact O-N 3.44Å; A542-V545 PolarHBondContact O-N 3.11Å
546Q95.8Very high97.5Very high64 Ų6439.4 Ų39.430%0.29922%0.219SC..  trans-128.788.3179.6-172.5175.3-14.600110.8V516 A542 V543 D548 F549V516-Q546 HydrophobicContact CB-CB 4.49Å; V516-Q546 HydrophobicContact CG1-CB 3.91Å; V516-Q546 HydrophobicContact CG2-CB 4.22Å; V516-Q546 VanDerWaalsContact CG2-OE1 3.28Å; A542-Q546 PolarHBondContact O-N 3.21Å; V543-Q546 CarbonylContact O-C 3.2Å; Q546-D548 VanDerWaalsContact C-N 3.26Å; Q546-D548 WeakPolarHBondContact CG-OD1 2.81Å; Q546-D548 PolarHBondContact NE2-OD1 2.93Å; Q546-D548 PolarHBondContact O-N 2.77Å; Q546-F549 HydrophobicContact CB-CB 4.28Å; Q546-F549 HydrophobicContact CG-CB 3.99Å; Q546-F549 WeakPolarHBondContact O-CB 3.41Å; Q546-F549 PolarHBondContact O-N 3.4Å
547P96.3Very high97.5Very high58 Ų5838 Ų3838%0.37721%0.212SC..THydrogen-bonded Turntrans-61.2-30.6-177.2-26.935.8000114.3V543 F549 W553 Y579V543-P547 WeakPolarHBondContact O-CA 3.16Å; P547-F549 PolarHBondContact O-N 2.66Å; P547-W553 PolarHBondContact O-NE1 3.43Å; P547-Y579 WeakPolarHBondContact CB-OH 3.5Å; P547-Y579 WeakPolarHBondContact O-CD2 3.22Å; P547-Y579 WeakPolarHBondContact O-CE2 3.26Å; P547-Y579 VanDerWaalsContact O-CZ 3.29Å
548D94.1Very high97.5Very high97 Ų9732.8 Ų32.852%0.51919%0.189SC..THydrogen-bonded Turntrans-80.31-178.871-14.1000114.4Q546 A550 Y579Q546-D548 VanDerWaalsContact C-N 3.26Å; Q546-D548 WeakPolarHBondContact CG-OD1 2.81Å; Q546-D548 PolarHBondContact NE2-OD1 2.93Å; Q546-D548 PolarHBondContact O-N 2.77Å; D548-A550 VanDerWaalsContact C-N 3.33Å; D548-A550 PolarHBondContact O-N 3.23Å; D548-Y579 HydrophobicContact CB-CD1 3.69Å; D548-Y579 HydrophobicContact CB-CE1 3.89Å; D548-Y579 HydrophobicContact CB-CG 4.3Å
549F96.4Very high97.5Very high30 Ų3031.8 Ų31.813%0.13218%0.183CC..  trans-78.578.2179-170-162.2000112V516 H517 N520 Q546 P547 A551 A552 W553V516-F549 HydrophobicContact CB-CD1 4.1Å; V516-F549 HydrophobicContact CB-CE1 4.39Å; V516-F549 HydrophobicContact CG2-CD1 3.96Å; V516-F549 HydrophobicContact CG2-CE1 4.23Å; H517-F549 AromaticContact ND1-CE1 3.8Å; H517-F549 AromaticContact ND1-CZ 3.54Å; N520-F549 HydrophobicContact CB-CE1 3.68Å; N520-F549 HydrophobicContact CB-CZ 4.02Å; Q546-F549 HydrophobicContact CB-CB 4.28Å; Q546-F549 HydrophobicContact CG-CB 3.99Å; Q546-F549 WeakPolarHBondContact O-CB 3.41Å; Q546-F549 PolarHBondContact O-N 3.4Å; P547-F549 PolarHBondContact O-N 2.66Å; F549-A551 HydrophobicContact CD2-CB 4.23Å; F549-A551 HydrophobicContact CE2-CB 3.73Å; F549-A551 HydrophobicContact CZ-CB 4.31Å; F549-A551 PolarHBondContact O-N 2.94Å; F549-A552 HydrophobicContact CB-CB 4.37Å; F549-A552 HydrophobicContact CD1-CB 3.52Å; F549-A552 HydrophobicContact CE1-CB 3.93Å; F549-A552 HydrophobicContact CG-CB 3.97Å; F549-A552 PolarHBondContact O-N 3.43Å; F549-W553 PolarHBondContact O-N 3.34Å
550A96.9Very high97.5Very high9 Ų932.5 Ų32.57%0.07419%0.187CC..Hα-helixtrans-52.9-33.3-174.400000115.1D548 W553 M554 A576 R580 Y583D548-A550 VanDerWaalsContact C-N 3.33Å; D548-A550 PolarHBondContact O-N 3.23Å; A550-W553 PolarHBondContact O-N 3.49Å; A550-M554 PolarHBondContact O-N 3.32Å; A550-M554 VanDerWaalsContact O-N 3.1Å; A550-A576 WeakPolarHBondContact O-CB 3.41Å; A550-R580 HydrophobicContact CB-CB 3.63Å; A550-Y583 HydrophobicContact CB-CE1 4.42Å
551A97.6Very high97.5Very high23 Ų2331.2 Ų31.219%0.1918%0.176CC..Hα-helixtrans-68.1-36.8178.900000112.4F549 M554 N555F549-A551 HydrophobicContact CD2-CB 4.23Å; F549-A551 HydrophobicContact CE2-CB 3.73Å; F549-A551 HydrophobicContact CZ-CB 4.31Å; F549-A551 PolarHBondContact O-N 2.94Å; A551-M554 PolarHBondContact O-N 3.01Å; A551-N555 WeakPolarHBondContact O-CB 3.21Å; A551-N555 PolarHBondContact O-N 2.92Å; A551-N555 PolarHBondContact O-ND2 3.32Å
552A97.9Very high97.4Very high0 Ų030.2 Ų30.20%018%0.18CC..Hα-helixtrans-67.2-39.6176.100000111.5N520 L539 A542 V543 F549 N555 L556N520-A552 WeakPolarHBondContact OD1-CA 3.28Å; L539-A552 HydrophobicContact CD2-CB 4.46Å; A542-A552 HydrophobicContact CB-CB 4.22Å; V543-A552 HydrophobicContact CG1-CB 3.74Å; F549-A552 HydrophobicContact CB-CB 4.37Å; F549-A552 HydrophobicContact CD1-CB 3.52Å; F549-A552 HydrophobicContact CE1-CB 3.93Å; F549-A552 HydrophobicContact CG-CB 3.97Å; F549-A552 PolarHBondContact O-N 3.43Å; A552-N555 PolarHBondContact O-N 3.42Å; A552-L556 WeakPolarHBondContact O-CB 2.84Å; A552-L556 PolarHBondContact O-N 2.96Å
553W98.6Very high97.4Very high37 Ų3732.7 Ų32.714%0.1419%0.193CC..Hα-helixtrans-60.2-46172.6-81.1116.2000112.8V543 P547 F549 A550 N555 L556 G557 N575 A576 Y579V543-W553 HydrophobicContact CB-CD2 3.86Å; V543-W553 HydrophobicContact CB-CE3 4.24Å; V543-W553 HydrophobicContact CB-CG 4.4Å; V543-W553 HydrophobicContact CB-CH2 4.06Å; V543-W553 HydrophobicContact CB-CZ2 3.64Å; V543-W553 HydrophobicContact CB-CZ3 4.34Å; V543-W553 HydrophobicContact CG1-CB 4.38Å; V543-W553 HydrophobicContact CG1-CD2 3.57Å; V543-W553 HydrophobicContact CG1-CE3 4.02Å; V543-W553 HydrophobicContact CG1-CG 3.72Å; V543-W553 HydrophobicContact CG1-CZ2 4.33Å; V543-W553 HydrophobicContact CG2-CD2 4.27Å; V543-W553 HydrophobicContact CG2-CE3 4.15Å; V543-W553 HydrophobicContact CG2-CH2 3.69Å; V543-W553 HydrophobicContact CG2-CZ2 3.81Å; V543-W553 HydrophobicContact CG2-CZ3 3.87Å; P547-W553 PolarHBondContact O-NE1 3.43Å; F549-W553 PolarHBondContact O-N 3.34Å; A550-W553 PolarHBondContact O-N 3.49Å; W553-N555 PolarHBondContact O-N 2.91Å; W553-L556 HydrophobicContact CE3-CD2 4.07Å; W553-L556 HydrophobicContact CZ3-CD2 4Å; W553-L556 PolarHBondContact O-N 3.13Å; W553-G557 PolarHBondContact O-N 3.22Å; W553-N575 HydrophobicContact CD2-CB 3.61Å; W553-N575 HydrophobicContact CE3-CB 3.91Å; W553-N575 HydrophobicContact CG-CB 3.95Å; W553-N575 HydrophobicContact CH2-CB 4.48Å; W553-N575 HydrophobicContact CZ2-CB 4.22Å; W553-N575 HydrophobicContact CZ3-CB 4.33Å; W553-A576 HydrophobicContact CB-CB 3.67Å; W553-Y579 AromaticContact NE1-CE2 3.79Å
554M98.5Very high97.3Very high18 Ų1841.9 Ų41.99%0.08923%0.227CC..Hα-helixtrans-61.8-45.4176.9-175.1-172.471.300111A550 A551 L556 G557 I558 Y573 A576 Y583 D585 C586A550-M554 PolarHBondContact O-N 3.32Å; A550-M554 VanDerWaalsContact O-N 3.1Å; A551-M554 PolarHBondContact O-N 3.01Å; M554-L556 VanDerWaalsContact C-N 3.33Å; M554-L556 PolarHBondContact O-N 3.35Å; M554-G557 PolarHBondContact O-N 3.41Å; M554-I558 HydrophobicContact CG-CD1 4.37Å; M554-I558 WeakPolarHBondContact O-CG1 3.45Å; M554-I558 PolarHBondContact O-N 3.3Å; M554-Y573 HydrophobicContact CG-CD1 4.3Å; M554-Y573 HydrophobicContact CG-CE1 4.15Å; M554-Y573 WeakPolarHBondContact O-CE1 3.09Å; M554-A576 HydrophobicContact CB-CB 4.16Å; M554-Y583 HydrophobicContact CB-CE1 4.15Å; M554-Y583 HydrophobicContact CE-CE2 4.33Å; M554-Y583 WeakPolarHBondContact CE-OH 3.27Å; M554-Y583 HydrophobicContact SD-CE1 3.92Å; M554-Y583 HydrophobicContact SD-CE2 3.83Å; M554-D585 HydrophobicContact SD-CB 4.21Å; M554-C586 HydrophobicContact CG-CB 4.19Å; M554-C586 HydrophobicContact SD-CB 3.98Å
555N98.5Very high97.3Very high18 Ų1842.4 Ų42.410%0.09622%0.215CC..Hα-helixtrans-64.6-37.5178.1-73.6-23000112.3N520 L539 A551 A552 W553 I558 V559N520-N555 PolarHBondContact OD1-ND2 3.35Å; L539-N555 HydrophobicContact CD1-CB 3.98Å; L539-N555 HydrophobicContact CD2-CB 3.84Å; A551-N555 WeakPolarHBondContact O-CB 3.21Å; A551-N555 PolarHBondContact O-N 2.92Å; A551-N555 PolarHBondContact O-ND2 3.32Å; A552-N555 PolarHBondContact O-N 3.42Å; W553-N555 PolarHBondContact O-N 2.91Å; N555-I558 PolarHBondContact O-N 3Å; N555-V559 WeakPolarHBondContact O-CG2 3.4Å; N555-V559 PolarHBondContact O-N 3.35Å; N555-V559 VanDerWaalsContact O-N 3.08Å
556L98.6Very high97.4Very high4 Ų441.8 Ų41.82%0.02121%0.207CC..Hα-helixtrans-60.5-46.1173.7-178.556.7000110.7E536 L539 S540 V543 A552 W553 M554 I558 V559 Q560E536-L556 HydrophobicContact CG-CD1 3.98Å; L539-L556 HydrophobicContact CB-CB 4Å; L539-L556 HydrophobicContact CB-CD1 3.92Å; L539-L556 HydrophobicContact CB-CG 4.48Å; S540-L556 WeakPolarHBondContact OG-CD1 3.47Å; V543-L556 HydrophobicContact CG2-CD2 3.92Å; A552-L556 WeakPolarHBondContact O-CB 2.84Å; A552-L556 PolarHBondContact O-N 2.96Å; W553-L556 HydrophobicContact CE3-CD2 4.07Å; W553-L556 HydrophobicContact CZ3-CD2 4Å; W553-L556 PolarHBondContact O-N 3.13Å; M554-L556 VanDerWaalsContact C-N 3.33Å; M554-L556 PolarHBondContact O-N 3.35Å; L556-I558 VanDerWaalsContact C-N 3.31Å; L556-I558 PolarHBondContact O-N 2.89Å; L556-V559 PolarHBondContact O-N 3.26Å; L556-Q560 HydrophobicContact CD1-CG 4.11Å; L556-Q560 HydrophobicContact CG-CG 4.36Å; L556-Q560 WeakPolarHBondContact O-CB 3.4Å; L556-Q560 VanDerWaalsContact O-CG 3.3Å; L556-Q560 WeakPolarHBondContact O-CG 3.42Å; L556-Q560 PolarHBondContact O-N 3.11Å
557G98.4Very high97.5Very high0 Ų045.7 Ų45.70%023%0.225CC..Hα-helixtrans-60.2-37.8176.100000113.3W553 M554 N561 A569 Y573W553-G557 PolarHBondContact O-N 3.22Å; M554-G557 PolarHBondContact O-N 3.41Å; G557-N561 WeakPolarHBondContact O-CB 3.36Å; G557-N561 PolarHBondContact O-N 2.93Å; G557-A569 WeakPolarHBondContact O-CB 3.27Å; G557-Y573 VanDerWaalsContact C-CZ 3.47Å; G557-Y573 VanDerWaalsContact C-OH 3.24Å; G557-Y573 PolarHBondContact O-OH 3.26Å
558I98.3Very high97.5Very high29 Ų2944.5 Ų44.515%0.14922%0.22CC..Hα-helixtrans-65.1-45176.3-64.6165.5000110.9K527 M554 N555 L556 N561 S562 Y573 N589K527-I558 HydrophobicContact CD-CG2 3.8Å; M554-I558 HydrophobicContact CG-CD1 4.37Å; M554-I558 WeakPolarHBondContact O-CG1 3.45Å; M554-I558 PolarHBondContact O-N 3.3Å; N555-I558 PolarHBondContact O-N 3Å; L556-I558 VanDerWaalsContact C-N 3.31Å; L556-I558 PolarHBondContact O-N 2.89Å; I558-N561 PolarHBondContact O-N 3.47Å; I558-S562 PolarHBondContact O-N 3.11Å; I558-S562 VanDerWaalsContact O-N 3.08Å; I558-S562 PolarHBondContact O-OG 3.48Å; I558-Y573 VanDerWaalsContact CA-OH 3.24Å; I558-Y573 WeakPolarHBondContact CA-OH 3.4Å; I558-Y573 HydrophobicContact CG1-CE1 4.1Å; I558-Y573 WeakPolarHBondContact CG1-OH 3.31Å; I558-Y573 PolarHBondContact N-OH 2.8Å; I558-Y573 VanDerWaalsContact N-OH 3.16Å; I558-N589 HydrophobicContact CG1-CB 4.4Å
559V98.4Very high97.8Very high1 Ų139.9 Ų39.91%0.00620%0.195CC..Hα-helixtrans-65.4-45.4178.3173.40000110.7K527 L532 A535 E536 L539 N555 L556 N561 S562 L563K527-V559 HydrophobicContact CB-CG2 3.94Å; K527-V559 HydrophobicContact CD-CG2 4.4Å; K527-V559 HydrophobicContact CG-CG2 3.91Å; L532-V559 HydrophobicContact CB-CG1 4.34Å; L532-V559 HydrophobicContact CD2-CG1 4.47Å; L532-V559 VanDerWaalsContact O-CG1 3.3Å; L532-V559 WeakPolarHBondContact O-CG1 3.36Å; A535-V559 HydrophobicContact CB-CG1 4.21Å; A535-V559 HydrophobicContact CB-CG2 4.02Å; E536-V559 HydrophobicContact CB-CG1 3.85Å; L539-V559 HydrophobicContact CD1-CG2 3.82Å; N555-V559 WeakPolarHBondContact O-CG2 3.4Å; N555-V559 PolarHBondContact O-N 3.35Å; N555-V559 VanDerWaalsContact O-N 3.08Å; L556-V559 PolarHBondContact O-N 3.26Å; V559-N561 PolarHBondContact O-N 3.21Å; V559-S562 WeakPolarHBondContact O-CB 3.44Å; V559-S562 PolarHBondContact O-N 2.92Å; V559-S562 VanDerWaalsContact O-N 3.15Å; V559-L563 HydrophobicContact CG1-CD1 4.06Å; V559-L563 WeakPolarHBondContact O-CG 3.29Å; V559-L563 PolarHBondContact O-N 3.01Å
560Q98.5Very high97.9Very high16 Ų1640.3 Ų40.38%0.07520%0.198CC..Hα-helixtrans-61.7-41177.1-74.3170.9-27.400112.3E536 L556 S562 L563 R564 K565 A568 A569 S572E536-Q560 HydrophobicContact CG-CG 4.46Å; L556-Q560 HydrophobicContact CD1-CG 4.11Å; L556-Q560 HydrophobicContact CG-CG 4.36Å; L556-Q560 WeakPolarHBondContact O-CB 3.4Å; L556-Q560 VanDerWaalsContact O-CG 3.3Å; L556-Q560 WeakPolarHBondContact O-CG 3.42Å; L556-Q560 PolarHBondContact O-N 3.11Å; Q560-S562 VanDerWaalsContact C-N 3.32Å; Q560-S562 PolarHBondContact O-N 3.27Å; Q560-L563 CarbonylContact O-C 3.56Å; Q560-L563 PolarHBondContact O-N 3.43Å; Q560-R564 PolarHBondContact O-N 3.01Å; Q560-R564 VanDerWaalsContact O-N 3.13Å; Q560-K565 HydrophobicContact CB-CB 4.19Å; Q560-K565 PolarHBondContact O-N 3.49Å; Q560-A568 PolarHBondContact OE1-O 2.61Å; Q560-A569 HydrophobicContact CB-CB 3.81Å; Q560-S572 PolarHBondContact OE1-OG 3.11Å
561N97.7Very high97.9Very high16 Ų1645.8 Ų45.89%0.08622%0.222CC..Hα-helixtrans-61.1-42.8174-172.344.5000111.3G557 I558 V559 L563 R564 F566 A569 L593 D596G557-N561 WeakPolarHBondContact O-CB 3.36Å; G557-N561 PolarHBondContact O-N 2.93Å; I558-N561 PolarHBondContact O-N 3.47Å; V559-N561 PolarHBondContact O-N 3.21Å; N561-L563 PolarHBondContact O-N 2.94Å; N561-R564 WeakPolarHBondContact O-CA 3.39Å; N561-R564 PolarHBondContact O-N 3.49Å; N561-F566 VanDerWaalsContact OD1-CD1 3.3Å; N561-F566 WeakPolarHBondContact OD1-CD1 3.35Å; N561-F566 VanDerWaalsContact OD1-CE1 3.26Å; N561-F566 WeakPolarHBondContact OD1-CE1 3.39Å; N561-A569 HydrophobicContact CB-CB 4.13Å; N561-L593 HydrophobicContact CB-CD1 4.25Å; N561-L593 WeakPolarHBondContact OD1-CD1 3.42Å; N561-D596 PolarHBondContact ND2-OD2 3.1Å
562S96.4Very high98Very high66 Ų6644.9 Ų44.946%0.46221%0.214SC..Hα-helixtrans-64-31.5177.1-53.30000112.3I558 V559 Q560 R564I558-S562 PolarHBondContact O-N 3.11Å; I558-S562 VanDerWaalsContact O-N 3.08Å; I558-S562 PolarHBondContact O-OG 3.48Å; V559-S562 WeakPolarHBondContact O-CB 3.44Å; V559-S562 PolarHBondContact O-N 2.92Å; V559-S562 VanDerWaalsContact O-N 3.15Å; Q560-S562 VanDerWaalsContact C-N 3.32Å; Q560-S562 PolarHBondContact O-N 3.27Å; S562-R564 VanDerWaalsContact C-N 3.26Å; S562-R564 PolarHBondContact O-N 2.9Å
563L96.7Very high98Very high52 Ų5245 Ų4527%0.27222%0.215SC..THydrogen-bonded Turntrans-81.22.4172-69.7170.5000113.8L532 E536 V559 Q560 N561 K565L532-L563 HydrophobicContact CB-CD1 4.32Å; L532-L563 HydrophobicContact CB-CD2 3.67Å; L532-L563 HydrophobicContact CB-CG 3.94Å; L532-L563 HydrophobicContact CD1-CD2 3.98Å; L532-L563 HydrophobicContact CD1-CG 4.23Å; E536-L563 HydrophobicContact CB-CD1 4.15Å; E536-L563 HydrophobicContact CG-CD1 4.42Å; E536-L563 WeakPolarHBondContact OE2-CD1 3.13Å; V559-L563 HydrophobicContact CG1-CD1 4.06Å; V559-L563 WeakPolarHBondContact O-CG 3.29Å; V559-L563 PolarHBondContact O-N 3.01Å; Q560-L563 CarbonylContact O-C 3.56Å; Q560-L563 PolarHBondContact O-N 3.43Å; N561-L563 PolarHBondContact O-N 2.94Å; L563-K565 HydrophobicContact CB-CD 4.25Å; L563-K565 HydrophobicContact CB-CG 4.22Å; L563-K565 HydrophobicContact CD1-CD 4.49Å; L563-K565 PolarHBondContact O-N 3.08Å
564R96Very high98Very high202 Ų20249 Ų4976%0.76223%0.23SC*.THydrogen-bonded Turntrans59.724.5-174.6-55.5-175.2173.3-151-2.2114.8Q560 N561 S562 F566Q560-R564 PolarHBondContact O-N 3.01Å; Q560-R564 VanDerWaalsContact O-N 3.13Å; N561-R564 WeakPolarHBondContact O-CA 3.39Å; N561-R564 PolarHBondContact O-N 3.49Å; S562-R564 VanDerWaalsContact C-N 3.26Å; S562-R564 PolarHBondContact O-N 2.9Å; R564-F566 VanDerWaalsContact C-N 3.27Å; R564-F566 HydrophobicContact CB-CE1 4.47Å; R564-F566 HydrophobicContact CB-CE2 4.29Å; R564-F566 HydrophobicContact CB-CZ 4.09Å; R564-F566 HydrophobicContact CG-CZ 4.21Å; R564-F566 PolarHBondContact O-N 2.85Å
565K97.8Very high98Very high88 Ų8849.4 Ų49.438%0.38323%0.232SC..  trans-87.468.4171.9-64.6175.1173.9179.90109.2E536 Q560 L563 E567 A568 A569E536-K565 VanDerWaalsContact OE1-CD 3.27Å; E536-K565 WeakPolarHBondContact OE1-CD 3.37Å; E536-K565 IonicContact OE1-NZ 2.68Å; E536-K565 PolarHBondContact OE1-NZ 2.96Å; E536-K565 IonicContact OE2-NZ 2.74Å; E536-K565 PolarHBondContact OE2-NZ 3.48Å; Q560-K565 HydrophobicContact CB-CB 4.19Å; Q560-K565 PolarHBondContact O-N 3.49Å; L563-K565 HydrophobicContact CB-CD 4.25Å; L563-K565 HydrophobicContact CB-CG 4.22Å; L563-K565 HydrophobicContact CD1-CD 4.49Å; L563-K565 PolarHBondContact O-N 3.08Å; K565-E567 PolarHBondContact O-N 3.22Å; K565-A568 HydrophobicContact CB-CB 4.31Å; K565-A568 PolarHBondContact O-N 2.88Å; K565-A569 WeakPolarHBondContact O-CB 3.43Å; K565-A569 PolarHBondContact O-N 2.51Å
566F97.6Very high98Very high50 Ų5048.5 Ų48.522%0.21923%0.228CC..Hα-helixtrans-64.6-41-165-66.8-46.2000114.1N561 R564 A569 E570 L593 D596 Q597N561-F566 VanDerWaalsContact OD1-CD1 3.3Å; N561-F566 WeakPolarHBondContact OD1-CD1 3.35Å; N561-F566 VanDerWaalsContact OD1-CE1 3.26Å; N561-F566 WeakPolarHBondContact OD1-CE1 3.39Å; R564-F566 VanDerWaalsContact C-N 3.27Å; R564-F566 HydrophobicContact CB-CE1 4.47Å; R564-F566 HydrophobicContact CB-CE2 4.29Å; R564-F566 HydrophobicContact CB-CZ 4.09Å; R564-F566 HydrophobicContact CG-CZ 4.21Å; R564-F566 PolarHBondContact O-N 2.85Å; F566-A569 PolarHBondContact O-N 3.04Å; F566-E570 PolarHBondContact O-N 3.15Å; F566-L593 HydrophobicContact CB-CD1 4.15Å; F566-L593 HydrophobicContact CD1-CD1 3.56Å; F566-L593 HydrophobicContact CE1-CD1 4.44Å; F566-L593 HydrophobicContact CG-CD1 4.28Å; F566-D596 HydrophobicContact CE1-CB 4.17Å; F566-Q597 HydrophobicContact CB-CG 4.11Å; F566-Q597 HydrophobicContact CD1-CG 4.24Å; F566-Q597 HydrophobicContact CD2-CG 4.14Å; F566-Q597 HydrophobicContact CG-CG 3.92Å
567E97.6Very high97.9Very high145 Ų14548.8 Ų48.868%0.67823%0.229SC*.Hα-helixtrans-66.3-45179.7-62.374.5-164.300110.9K565 A569 E570 E571K565-E567 PolarHBondContact O-N 3.22Å; E567-A569 VanDerWaalsContact C-N 3.33Å; E567-A569 PolarHBondContact O-N 3.07Å; E567-E570 PolarHBondContact O-N 3.4Å; E567-E571 PolarHBondContact O-N 2.89Å
568A98.2Very high97.9Very high33 Ų3357.3 Ų57.327%0.27326%0.261SS..Hα-helixtrans-64.4-38.8176.600000111.7Q560 K565 E571 S572Q560-A568 PolarHBondContact OE1-O 2.61Å; K565-A568 HydrophobicContact CB-CB 4.31Å; K565-A568 PolarHBondContact O-N 2.88Å; A568-E571 PolarHBondContact O-N 3.47Å; A568-S572 WeakPolarHBondContact O-CB 3.34Å; A568-S572 PolarHBondContact O-N 3.46Å; A568-S572 PolarHBondContact O-OG 2.64Å; A568-S572 VanDerWaalsContact O-OG 3.12Å
569A98.5Very high97.8Very high0 Ų060.5 Ų60.50%027%0.272CS..Hα-helixtrans-62.8-43.4175.900000112G557 Q560 N561 K565 F566 E567 S572 Y573 L593G557-A569 WeakPolarHBondContact O-CB 3.27Å; Q560-A569 HydrophobicContact CB-CB 3.81Å; N561-A569 HydrophobicContact CB-CB 4.13Å; K565-A569 WeakPolarHBondContact O-CB 3.43Å; K565-A569 PolarHBondContact O-N 2.51Å; F566-A569 PolarHBondContact O-N 3.04Å; E567-A569 VanDerWaalsContact C-N 3.33Å; E567-A569 PolarHBondContact O-N 3.07Å; A569-S572 PolarHBondContact O-N 2.84Å; A569-Y573 HydrophobicContact CB-CE2 4.38Å; A569-Y573 WeakPolarHBondContact O-CD2 3.45Å; A569-Y573 PolarHBondContact O-N 2.9Å; A569-L593 HydrophobicContact CB-CD1 4Å; A569-L593 HydrophobicContact CB-CD2 4.02Å
570E98.4Very high97.6Very high39 Ų3966.6 Ų66.618%0.18230%0.295CS..Hα-helixtrans-60-48176.3-177.7161.7-167.400111F566 E567 S572 Y573 W574 L590 L593 Y594 R599F566-E570 PolarHBondContact O-N 3.15Å; E567-E570 PolarHBondContact O-N 3.4Å; E570-S572 VanDerWaalsContact C-N 3.34Å; E570-S572 PolarHBondContact O-N 3.45Å; E570-Y573 PolarHBondContact O-N 3.3Å; E570-W574 PolarHBondContact O-N 3.21Å; E570-L590 HydrophobicContact CG-CD1 4.41Å; E570-L593 HydrophobicContact CB-CD2 3.71Å; E570-Y594 HydrophobicContact CG-CE1 4.34Å; E570-Y594 VanDerWaalsContact OE1-CE1 3.26Å; E570-Y594 WeakPolarHBondContact OE1-CE1 3.34Å; E570-Y594 PolarHBondContact OE1-OH 3.07Å; E570-R599 IonicContact OE1-NH1 2.85Å; E570-R599 IonicContact OE1-NH2 3.12Å; E570-R599 IonicContact OE2-CZ 2.84Å; E570-R599 IonicContact OE2-NH1 3.89Å; E570-R599 PolarHBondContact OE2-NH1 3.44Å
571E98.4Very high97.3Very high125 Ų12576 Ų7658%0.58433%0.33SS*.Hα-helixtrans-57.7-46.5176.1-171.8-174.4173.300111.6E567 A568 Y573 W574 N575E567-E571 PolarHBondContact O-N 2.89Å; A568-E571 PolarHBondContact O-N 3.47Å; E571-Y573 PolarHBondContact O-N 3.11Å; E571-W574 PolarHBondContact O-N 3.41Å; E571-N575 PolarHBondContact O-N 3.07Å; E571-N575 PolarHBondContact O-ND2 2.84Å
572S98.6Very high97.2Very high3 Ų383.4 Ų83.42%0.02136%0.361CS..Hα-helixtrans-59.2-43.8178-70.90000112.4Q560 A568 A569 E570 N575 A576Q560-S572 PolarHBondContact OE1-OG 3.11Å; A568-S572 WeakPolarHBondContact O-CB 3.34Å; A568-S572 PolarHBondContact O-N 3.46Å; A568-S572 PolarHBondContact O-OG 2.64Å; A568-S572 VanDerWaalsContact O-OG 3.12Å; A569-S572 PolarHBondContact O-N 2.84Å; E570-S572 VanDerWaalsContact C-N 3.34Å; E570-S572 PolarHBondContact O-N 3.45Å; S572-N575 PolarHBondContact O-N 2.92Å; S572-A576 PolarHBondContact O-N 2.89Å
573Y98.6Very high97.3Very high3 Ų381.1 Ų81.11%0.01234%0.342CS..Hα-helixtrans-65.8-39.8175.8-68.2-48.8000112.6M554 G557 I558 A569 E570 E571 N575 A576 L577 N589 L590 L593M554-Y573 HydrophobicContact CG-CD1 4.3Å; M554-Y573 HydrophobicContact CG-CE1 4.15Å; M554-Y573 WeakPolarHBondContact O-CE1 3.09Å; G557-Y573 VanDerWaalsContact C-CZ 3.47Å; G557-Y573 VanDerWaalsContact C-OH 3.24Å; G557-Y573 PolarHBondContact O-OH 3.26Å; I558-Y573 VanDerWaalsContact CA-OH 3.24Å; I558-Y573 WeakPolarHBondContact CA-OH 3.4Å; I558-Y573 HydrophobicContact CG1-CE1 4.1Å; I558-Y573 WeakPolarHBondContact CG1-OH 3.31Å; I558-Y573 PolarHBondContact N-OH 2.8Å; I558-Y573 VanDerWaalsContact N-OH 3.16Å; A569-Y573 HydrophobicContact CB-CE2 4.38Å; A569-Y573 WeakPolarHBondContact O-CD2 3.45Å; A569-Y573 PolarHBondContact O-N 2.9Å; E570-Y573 PolarHBondContact O-N 3.3Å; E571-Y573 PolarHBondContact O-N 3.11Å; Y573-N575 VanDerWaalsContact C-N 3.34Å; Y573-A576 WeakPolarHBondContact O-CB 3.47Å; Y573-A576 PolarHBondContact O-N 2.93Å; Y573-L577 WeakPolarHBondContact O-CG 3.33Å; Y573-L577 PolarHBondContact O-N 3.34Å; Y573-N589 HydrophobicContact CD1-CB 4.48Å; Y573-N589 HydrophobicContact CE1-CB 3.66Å; Y573-L590 HydrophobicContact CD2-CB 4.38Å; Y573-L590 HydrophobicContact CD2-CD1 3.83Å; Y573-L590 HydrophobicContact CG-CB 4.5Å; Y573-L590 HydrophobicContact CG-CD1 4.24Å; Y573-L593 HydrophobicContact CD2-CD2 3.79Å; Y573-L593 HydrophobicContact CE2-CB 4.03Å; Y573-L593 HydrophobicContact CE2-CD2 3.87Å
574W98.4Very high97.3Very high121 Ų12179.7 Ų79.746%0.45834%0.336SS..Hα-helixtrans-65.8-37.2175.5-77.4117.4000112.3E570 E571 L577 R578 L590E570-W574 PolarHBondContact O-N 3.21Å; E571-W574 PolarHBondContact O-N 3.41Å; W574-L577 HydrophobicContact CE3-CD1 4.01Å; W574-L577 HydrophobicContact CZ3-CD1 4.13Å; W574-L577 PolarHBondContact O-N 3Å; W574-R578 WeakPolarHBondContact O-CB 2.91Å; W574-R578 PolarHBondContact O-N 3.42Å; W574-L590 HydrophobicContact CZ2-CD2 4.09Å
575N98.3Very high97.4Very high26 Ų2673.3 Ų73.314%0.13932%0.317CS..Hα-helixtrans-63.3-43.9171.2-78.9-37.8000111.5W553 E571 S572 Y573 L577 R578 Y579W553-N575 HydrophobicContact CD2-CB 3.61Å; W553-N575 HydrophobicContact CE3-CB 3.91Å; W553-N575 HydrophobicContact CG-CB 3.95Å; W553-N575 HydrophobicContact CH2-CB 4.48Å; W553-N575 HydrophobicContact CZ2-CB 4.22Å; W553-N575 HydrophobicContact CZ3-CB 4.33Å; E571-N575 PolarHBondContact O-N 3.07Å; E571-N575 PolarHBondContact O-ND2 2.84Å; S572-N575 PolarHBondContact O-N 2.92Å; Y573-N575 VanDerWaalsContact C-N 3.34Å; N575-L577 VanDerWaalsContact C-N 3.31Å; N575-L577 PolarHBondContact O-N 2.86Å; N575-R578 WeakPolarHBondContact O-CB 3.47Å; N575-R578 PolarHBondContact O-N 3.33Å; N575-R578 VanDerWaalsContact O-N 3.16Å; N575-Y579 WeakPolarHBondContact O-CD2 3.36Å; N575-Y579 PolarHBondContact O-N 3.37Å; N575-Y579 VanDerWaalsContact O-N 3.16Å
576A98.3Very high97.4Very high0 Ų069.1 Ų69.10%030%0.299CS..Hα-helixtrans-56.4-44.9173.700000112A550 W553 M554 S572 Y573 Y579 R580A550-A576 WeakPolarHBondContact O-CB 3.41Å; W553-A576 HydrophobicContact CB-CB 3.67Å; M554-A576 HydrophobicContact CB-CB 4.16Å; S572-A576 PolarHBondContact O-N 2.89Å; Y573-A576 WeakPolarHBondContact O-CB 3.47Å; Y573-A576 PolarHBondContact O-N 2.93Å; A576-Y579 PolarHBondContact O-N 2.99Å; A576-R580 PolarHBondContact O-N 3.41Å
577L97.6Very high97.4Very high9 Ų968.5 Ų68.55%0.04730%0.296CS..Hα-helixtrans-69.9-30.4178-71169.7000113.3Y573 W574 N575 R580 R581 C586 Y587 L590Y573-L577 WeakPolarHBondContact O-CG 3.33Å; Y573-L577 PolarHBondContact O-N 3.34Å; W574-L577 HydrophobicContact CE3-CD1 4.01Å; W574-L577 HydrophobicContact CZ3-CD1 4.13Å; W574-L577 PolarHBondContact O-N 3Å; N575-L577 VanDerWaalsContact C-N 3.31Å; N575-L577 PolarHBondContact O-N 2.86Å; L577-R580 CarbonylContact O-C 3.44Å; L577-R581 WeakPolarHBondContact O-CA 3.43Å; L577-R581 PolarHBondContact O-N 2.9Å; L577-C586 HydrophobicContact CD2-CB 4.09Å; L577-C586 HydrophobicContact CG-CB 4.38Å; L577-Y587 HydrophobicContact CD1-CD1 4Å; L577-Y587 HydrophobicContact CD1-CE1 3.62Å; L577-Y587 HydrophobicContact CD1-CE2 4.37Å; L577-Y587 HydrophobicContact CD2-CD2 3.81Å; L577-Y587 HydrophobicContact CD2-CE1 4.29Å; L577-Y587 HydrophobicContact CD2-CE2 3.49Å; L577-Y587 VanDerWaalsContact CD2-CE2 3.49Å; L577-Y587 HydrophobicContact CD2-CG 4.34Å; L577-L590 HydrophobicContact CD1-CD2 4.41Å
578R97.4Very high97.5Very high179 Ų17963 Ų6368%0.67527%0.269SS*.Hα-helixtrans-61.2-46.7173.6-179.2-177.8179.6179.20.6111W574 N575W574-R578 WeakPolarHBondContact O-CB 2.91Å; W574-R578 PolarHBondContact O-N 3.42Å; N575-R578 WeakPolarHBondContact O-CB 3.47Å; N575-R578 PolarHBondContact O-N 3.33Å; N575-R578 VanDerWaalsContact O-N 3.16Å
579Y95.3Very high97.5Very high96 Ų9662.2 Ų62.238%0.37626%0.26SS..Hα-helixtrans-81.6-29.2179.5-65.4-69.1000112.9P547 D548 W553 N575 A576P547-Y579 WeakPolarHBondContact CB-OH 3.5Å; P547-Y579 WeakPolarHBondContact O-CD2 3.22Å; P547-Y579 WeakPolarHBondContact O-CE2 3.26Å; P547-Y579 VanDerWaalsContact O-CZ 3.29Å; D548-Y579 HydrophobicContact CB-CD1 3.69Å; D548-Y579 HydrophobicContact CB-CE1 3.89Å; D548-Y579 HydrophobicContact CB-CG 4.3Å; W553-Y579 AromaticContact NE1-CE2 3.79Å; N575-Y579 WeakPolarHBondContact O-CD2 3.36Å; N575-Y579 PolarHBondContact O-N 3.37Å; N575-Y579 VanDerWaalsContact O-N 3.16Å; A576-Y579 PolarHBondContact O-N 2.99Å
580R96.1Very high97.5Very high129 Ų12962.3 Ų62.349%0.48726%0.261SS..  trans-131.891.2175.4-172.2-176.1-119.1178.1-1.1111.4A550 A576 L577 K582 Y583A550-R580 HydrophobicContact CB-CB 3.63Å; A576-R580 PolarHBondContact O-N 3.41Å; L577-R580 CarbonylContact O-C 3.44Å; R580-K582 PolarHBondContact O-N 3.07Å; R580-Y583 HydrophobicContact CB-CD1 4.1Å; R580-Y583 HydrophobicContact CG-CD1 4.17Å; R580-Y583 HydrophobicContact CG-CG 4.23Å; R580-Y583 WeakPolarHBondContact O-CB 3.37Å
581R92.3Very high97.4Very high213 Ų21360.5 Ų60.580%0.80425%0.252SS*.SBendtrans-60.6-38.5-177.7-66.2-176.6178.9-177.4-1.2114.5L577 Y583L577-R581 WeakPolarHBondContact O-CA 3.43Å; L577-R581 PolarHBondContact O-N 2.9Å; R581-Y583 PolarHBondContact O-N 3.49Å
582K95.2Very high97.4Very high173 Ų17359.9 Ų59.975%0.75225%0.245SC*.SBendtrans-95.579.7178.5-66.1-174.2179.3-176.30109.7R580 L613R580-K582 PolarHBondContact O-N 3.07Å; K582-L613 HydrophobicContact CG-CD2 4.24Å
583Y97.3Very high97.4Very high17 Ų1759.8 Ų59.87%0.06724%0.244CC..  trans-13381.2-177.4-154.8173.6000112.2A550 M554 R580 R581 D585 C586 Y587A550-Y583 HydrophobicContact CB-CE1 4.42Å; M554-Y583 HydrophobicContact CB-CE1 4.15Å; M554-Y583 HydrophobicContact CE-CE2 4.33Å; M554-Y583 WeakPolarHBondContact CE-OH 3.27Å; M554-Y583 HydrophobicContact SD-CE1 3.92Å; M554-Y583 HydrophobicContact SD-CE2 3.83Å; R580-Y583 HydrophobicContact CB-CD1 4.1Å; R580-Y583 HydrophobicContact CG-CD1 4.17Å; R580-Y583 HydrophobicContact CG-CG 4.23Å; R580-Y583 WeakPolarHBondContact O-CB 3.37Å; R581-Y583 PolarHBondContact O-N 3.49Å; Y583-D585 VanDerWaalsContact C-N 3.33Å; Y583-D585 HydrophobicContact CD2-CB 4.43Å; Y583-D585 HydrophobicContact CE2-CB 4.23Å; Y583-D585 PolarHBondContact O-N 3.2Å; Y583-C586 HydrophobicContact CD1-CB 3.67Å; Y583-C586 HydrophobicContact CD2-CB 4.21Å; Y583-C586 HydrophobicContact CE1-CB 4.28Å; Y583-C586 HydrophobicContact CG-CB 3.64Å; Y583-C586 WeakPolarHBondContact O-CB 3.24Å; Y583-C586 PolarHBondContact O-N 3.45Å; Y583-C586 VanDerWaalsContact O-N 3.11Å; Y583-Y587 PolarHBondContact O-N 2.95Å
584P97.4Very high97.4Very high22 Ų2260.2 Ų60.214%0.14325%0.245CC..Hα-helixtrans-54.9-45.1-175.9-20.827.8000113.4C586 Y587 Y588 A610 L613 K614P584-C586 PolarHBondContact O-N 3.43Å; P584-Y587 PolarHBondContact O-N 3.46Å; P584-Y588 PolarHBondContact O-N 3.26Å; P584-A610 WeakPolarHBondContact O-CB 3.39Å; P584-L613 HydrophobicContact CB-CB 4.34Å; P584-L613 HydrophobicContact CG-CB 3.79Å; P584-K614 HydrophobicContact CB-CB 3.69Å; P584-K614 HydrophobicContact CB-CD 4.44Å; P584-K614 HydrophobicContact CG-CB 3.69Å
585D97.4Very high97.3Very high68 Ų6855.7 Ų55.736%0.36423%0.233SC..Hα-helixtrans-64.8-30.8-178.2-52.5-44.9000112M554 Y583 Y588 N589 H617M554-D585 HydrophobicContact SD-CB 4.21Å; Y583-D585 VanDerWaalsContact C-N 3.33Å; Y583-D585 HydrophobicContact CD2-CB 4.43Å; Y583-D585 HydrophobicContact CE2-CB 4.23Å; Y583-D585 PolarHBondContact O-N 3.2Å; D585-Y588 WeakPolarHBondContact O-CB 3.2Å; D585-Y588 PolarHBondContact O-N 2.98Å; D585-N589 PolarHBondContact O-N 3.37Å; D585-N589 PolarHBondContact O-ND2 3.48Å; D585-H617 IonicContact OD1-CD2 2.86Å; D585-H617 IonicContact OD1-NE2 3.97Å
586C98.1Very high97.1Very high0 Ų058.5 Ų58.50%025%0.248CC..Hα-helixtrans-69.8-43.5175.1-168.90000111.3M554 L577 Y583 P584 Y588 N589 L590M554-C586 HydrophobicContact CG-CB 4.19Å; M554-C586 HydrophobicContact SD-CB 3.98Å; L577-C586 HydrophobicContact CD2-CB 4.09Å; L577-C586 HydrophobicContact CG-CB 4.38Å; Y583-C586 HydrophobicContact CD1-CB 3.67Å; Y583-C586 HydrophobicContact CD2-CB 4.21Å; Y583-C586 HydrophobicContact CE1-CB 4.28Å; Y583-C586 HydrophobicContact CG-CB 3.64Å; Y583-C586 WeakPolarHBondContact O-CB 3.24Å; Y583-C586 PolarHBondContact O-N 3.45Å; Y583-C586 VanDerWaalsContact O-N 3.11Å; P584-C586 PolarHBondContact O-N 3.43Å; C586-Y588 VanDerWaalsContact C-N 3.28Å; C586-Y588 PolarHBondContact O-N 3.01Å; C586-N589 PolarHBondContact O-N 2.97Å; C586-L590 WeakPolarHBondContact O-CB 3.46Å; C586-L590 PolarHBondContact O-N 2.99Å
587Y98.6Very high97Very high38 Ų3860.7 Ų60.715%0.14926%0.259CS..Hα-helixtrans-62.7-36.6172.3-81.2-64.2000112.2L577 Y583 P584 L590 G591 N609 L613L577-Y587 HydrophobicContact CD1-CD1 4Å; L577-Y587 HydrophobicContact CD1-CE1 3.62Å; L577-Y587 HydrophobicContact CD1-CE2 4.37Å; L577-Y587 HydrophobicContact CD2-CD2 3.81Å; L577-Y587 HydrophobicContact CD2-CE1 4.29Å; L577-Y587 HydrophobicContact CD2-CE2 3.49Å; L577-Y587 VanDerWaalsContact CD2-CE2 3.49Å; L577-Y587 HydrophobicContact CD2-CG 4.34Å; Y583-Y587 PolarHBondContact O-N 2.95Å; P584-Y587 PolarHBondContact O-N 3.46Å; Y587-L590 HydrophobicContact CD1-CD2 4.42Å; Y587-L590 PolarHBondContact O-N 2.99Å; Y587-G591 PolarHBondContact O-N 2.9Å; Y587-N609 HydrophobicContact CD1-CB 3.77Å; Y587-N609 HydrophobicContact CD2-CB 4.13Å; Y587-N609 HydrophobicContact CE1-CB 3.99Å; Y587-N609 HydrophobicContact CE2-CB 4.32Å; Y587-N609 HydrophobicContact CG-CB 3.85Å; Y587-L613 HydrophobicContact CD2-CD1 3.71Å; Y587-L613 HydrophobicContact CE2-CD1 3.72Å
588Y98.5Very high96.8Very high29 Ų2965.9 Ų65.911%0.11429%0.287CS..Hα-helixtrans-59.7-48.2173.9168.5-101.9000112.2P584 D585 C586 G591 R592 W607 H617 L619 A620 N623P584-Y588 PolarHBondContact O-N 3.26Å; D585-Y588 WeakPolarHBondContact O-CB 3.2Å; D585-Y588 PolarHBondContact O-N 2.98Å; C586-Y588 VanDerWaalsContact C-N 3.28Å; C586-Y588 PolarHBondContact O-N 3.01Å; Y588-G591 PolarHBondContact O-N 3.25Å; Y588-R592 HydrophobicContact CE1-CG 4.38Å; Y588-R592 PolarHBondContact O-N 2.89Å; Y588-R592 VanDerWaalsContact O-N 3.08Å; Y588-W607 AromaticContact CD2-CD1 3.93Å; Y588-W607 AromaticContact CD2-NE1 3.84Å; Y588-W607 PolarHBondContact O-NE1 3.17Å; Y588-H617 AromaticContact CD2-CE1 3.53Å; Y588-H617 AromaticContact CG-CE1 3.55Å; Y588-H617 AromaticContact CG-NE2 3.77Å; Y588-L619 HydrophobicContact CD2-CB 4.45Å; Y588-L619 HydrophobicContact CE2-CB 3.68Å; Y588-A620 HydrophobicContact CD2-CB 3.99Å; Y588-N623 WeakPolarHBondContact CE2-ND2 3.35Å
589N98.3Very high96.8Very high17 Ų1761.1 Ų61.19%0.09127%0.269CS..Hα-helixtrans-68.7-35.1178.2-71.6-46.6000112.7I558 Y573 D585 C586 G591 R592 L593I558-N589 HydrophobicContact CG1-CB 4.4Å; Y573-N589 HydrophobicContact CD1-CB 4.48Å; Y573-N589 HydrophobicContact CE1-CB 3.66Å; D585-N589 PolarHBondContact O-N 3.37Å; D585-N589 PolarHBondContact O-ND2 3.48Å; C586-N589 PolarHBondContact O-N 2.97Å; N589-G591 VanDerWaalsContact C-N 3.32Å; N589-G591 PolarHBondContact O-N 3.49Å; N589-R592 WeakPolarHBondContact O-CB 3.42Å; N589-R592 PolarHBondContact O-N 3.49Å; N589-L593 PolarHBondContact O-N 3.47Å
590L98.1Very high96.8Very high2 Ų259.8 Ų59.81%0.0127%0.266CS..Hα-helixtrans-61.8-41.2171.7-173.468.6000111.3E570 Y573 W574 L577 C586 Y587 R592 L593 Y594 A606E570-L590 HydrophobicContact CG-CD1 4.41Å; Y573-L590 HydrophobicContact CD2-CB 4.38Å; Y573-L590 HydrophobicContact CD2-CD1 3.83Å; Y573-L590 HydrophobicContact CG-CB 4.5Å; Y573-L590 HydrophobicContact CG-CD1 4.24Å; W574-L590 HydrophobicContact CZ2-CD2 4.09Å; L577-L590 HydrophobicContact CD1-CD2 4.41Å; C586-L590 WeakPolarHBondContact O-CB 3.46Å; C586-L590 PolarHBondContact O-N 2.99Å; Y587-L590 HydrophobicContact CD1-CD2 4.42Å; Y587-L590 PolarHBondContact O-N 2.99Å; L590-R592 VanDerWaalsContact C-N 3.32Å; L590-R592 PolarHBondContact O-N 3.08Å; L590-L593 HydrophobicContact CD1-CD2 4.18Å; L590-L593 WeakPolarHBondContact O-CB 2.97Å; L590-L593 PolarHBondContact O-N 3.11Å; L590-Y594 HydrophobicContact CD1-CE1 4.28Å; L590-Y594 HydrophobicContact CD1-CE2 3.94Å; L590-Y594 HydrophobicContact CD2-CE2 3.82Å; L590-Y594 HydrophobicContact CG-CD2 4.08Å; L590-Y594 HydrophobicContact CG-CE2 3.49Å; L590-Y594 VanDerWaalsContact CG-CE2 3.49Å; L590-Y594 WeakPolarHBondContact O-CD2 3.43Å; L590-Y594 PolarHBondContact O-N 3.23Å; L590-A606 HydrophobicContact CB-CB 4.43Å; L590-A606 HydrophobicContact CD2-CB 4.42Å; L590-A606 HydrophobicContact CG-CB 4.42Å
591G98Very high96.8Very high0 Ų058.5 Ų58.50%027%0.272CS..Hα-helixtrans-64.8-35174.300000113.2Y587 Y588 N589 Y594 A595 A603 W607Y587-G591 PolarHBondContact O-N 2.9Å; Y588-G591 PolarHBondContact O-N 3.25Å; N589-G591 VanDerWaalsContact C-N 3.32Å; N589-G591 PolarHBondContact O-N 3.49Å; G591-Y594 PolarHBondContact O-N 3.08Å; G591-A595 WeakPolarHBondContact O-CB 3.46Å; G591-A595 PolarHBondContact O-N 3.41Å; G591-A603 WeakPolarHBondContact O-CB 3.38Å; G591-W607 VanDerWaalsContact C-CZ2 3.48Å; G591-W607 WeakPolarHBondContact O-CZ2 3.13Å
592R98.1Very high97Very high113 Ų11351 Ų5143%0.42625%0.248SC..Hα-helixtrans-64.4-45.6171.7-70.7-174.566-173.3-0.1111.9Y588 N589 L590 Y594 A595 D596 W607Y588-R592 HydrophobicContact CE1-CG 4.38Å; Y588-R592 PolarHBondContact O-N 2.89Å; Y588-R592 VanDerWaalsContact O-N 3.08Å; N589-R592 WeakPolarHBondContact O-CB 3.42Å; N589-R592 PolarHBondContact O-N 3.49Å; L590-R592 VanDerWaalsContact C-N 3.32Å; L590-R592 PolarHBondContact O-N 3.08Å; R592-Y594 VanDerWaalsContact C-N 3.33Å; R592-Y594 PolarHBondContact O-N 3.26Å; R592-A595 WeakPolarHBondContact O-CB 3.47Å; R592-A595 PolarHBondContact O-N 3.24Å; R592-D596 PolarHBondContact O-N 3.42Å; R592-W607 HydrophobicContact CG-CZ2 4.28Å
593L98.1Very high97.2Very high0 Ų042.8 Ų42.80%021%0.212CC..Hα-helixtrans-55.6-48174.9170.167.3000111.4N561 F566 A569 E570 Y573 N589 L590 A595 D596 Q597N561-L593 HydrophobicContact CB-CD1 4.25Å; N561-L593 WeakPolarHBondContact OD1-CD1 3.42Å; F566-L593 HydrophobicContact CB-CD1 4.15Å; F566-L593 HydrophobicContact CD1-CD1 3.56Å; F566-L593 HydrophobicContact CE1-CD1 4.44Å; F566-L593 HydrophobicContact CG-CD1 4.28Å; A569-L593 HydrophobicContact CB-CD1 4Å; A569-L593 HydrophobicContact CB-CD2 4.02Å; E570-L593 HydrophobicContact CB-CD2 3.71Å; Y573-L593 HydrophobicContact CD2-CD2 3.79Å; Y573-L593 HydrophobicContact CE2-CB 4.03Å; Y573-L593 HydrophobicContact CE2-CD2 3.87Å; N589-L593 PolarHBondContact O-N 3.47Å; L590-L593 HydrophobicContact CD1-CD2 4.18Å; L590-L593 WeakPolarHBondContact O-CB 2.97Å; L590-L593 PolarHBondContact O-N 3.11Å; L593-A595 VanDerWaalsContact C-N 3.33Å; L593-A595 PolarHBondContact O-N 2.93Å; L593-D596 PolarHBondContact O-N 3.23Å; L593-Q597 WeakPolarHBondContact O-CG 3.48Å; L593-Q597 PolarHBondContact O-N 3.38Å; L593-Q597 VanDerWaalsContact O-N 3.09Å
594Y98.3Very high97.2Very high13 Ų1343.2 Ų43.25%0.05122%0.216CC..Hα-helixtrans-65.8-35.7178-66.6-35.2000113E570 L590 G591 R592 Q597 N598 R599 D602 A606E570-Y594 HydrophobicContact CG-CE1 4.34Å; E570-Y594 VanDerWaalsContact OE1-CE1 3.26Å; E570-Y594 WeakPolarHBondContact OE1-CE1 3.34Å; E570-Y594 PolarHBondContact OE1-OH 3.07Å; L590-Y594 HydrophobicContact CD1-CE1 4.28Å; L590-Y594 HydrophobicContact CD1-CE2 3.94Å; L590-Y594 HydrophobicContact CD2-CE2 3.82Å; L590-Y594 HydrophobicContact CG-CD2 4.08Å; L590-Y594 HydrophobicContact CG-CE2 3.49Å; L590-Y594 VanDerWaalsContact CG-CE2 3.49Å; L590-Y594 WeakPolarHBondContact O-CD2 3.43Å; L590-Y594 PolarHBondContact O-N 3.23Å; G591-Y594 PolarHBondContact O-N 3.08Å; R592-Y594 VanDerWaalsContact C-N 3.33Å; R592-Y594 PolarHBondContact O-N 3.26Å; Y594-Q597 CarbonylContact O-C 3.15Å; Y594-Q597 PolarHBondContact O-N 3.19Å; Y594-N598 PolarHBondContact O-N 2.89Å; Y594-R599 VanDerWaalsContact CE1-NH1 3.32Å; Y594-R599 WeakPolarHBondContact O-CA 3.27Å; Y594-R599 PolarHBondContact O-N 3.41Å; Y594-D602 HydrophobicContact CD1-CB 4.21Å; Y594-D602 VanDerWaalsContact CD2-C 3.49Å; Y594-D602 HydrophobicContact CD2-CB 3.47Å; Y594-D602 VanDerWaalsContact CD2-CB 3.47Å; Y594-D602 HydrophobicContact CE2-CB 3.79Å; Y594-D602 HydrophobicContact CG-CB 3.68Å; Y594-A606 HydrophobicContact CD2-CB 4.22Å; Y594-A606 HydrophobicContact CE2-CB 4.4Å
595A96Very high97.2Very high25 Ų2546.1 Ų46.121%0.20723%0.23CC..Hα-helixtrans-63.7-42.4173.400000111.7G591 R592 L593 Q597 N598 A603 W607G591-A595 WeakPolarHBondContact O-CB 3.46Å; G591-A595 PolarHBondContact O-N 3.41Å; R592-A595 WeakPolarHBondContact O-CB 3.47Å; R592-A595 PolarHBondContact O-N 3.24Å; L593-A595 VanDerWaalsContact C-N 3.33Å; L593-A595 PolarHBondContact O-N 2.93Å; A595-Q597 PolarHBondContact O-N 3.42Å; A595-N598 PolarHBondContact O-N 2.95Å; A595-A603 HydrophobicContact CB-CB 4.23Å; A595-W607 HydrophobicContact CB-CH2 3.82Å; A595-W607 HydrophobicContact CB-CZ2 4.19Å
596D94.9Very high97.2Very high85 Ų8543.1 Ų43.146%0.45521%0.214SC..Hα-helixtrans-63.4-28.8176.3-67-21.8000112.1N561 F566 R592 L593 N598N561-D596 PolarHBondContact ND2-OD2 3.1Å; F566-D596 HydrophobicContact CE1-CB 4.17Å; R592-D596 PolarHBondContact O-N 3.42Å; L593-D596 PolarHBondContact O-N 3.23Å; D596-N598 VanDerWaalsContact C-N 3.35Å
597Q95.4Very high97.3Very high46 Ų4643.5 Ų43.522%0.21522%0.216CC..THydrogen-bonded Turntrans-84.81.1172.7-66.9177.537.500114.2F566 L593 Y594 A595 R599F566-Q597 HydrophobicContact CB-CG 4.11Å; F566-Q597 HydrophobicContact CD1-CG 4.24Å; F566-Q597 HydrophobicContact CD2-CG 4.14Å; F566-Q597 HydrophobicContact CG-CG 3.92Å; L593-Q597 WeakPolarHBondContact O-CG 3.48Å; L593-Q597 PolarHBondContact O-N 3.38Å; L593-Q597 VanDerWaalsContact O-N 3.09Å; Y594-Q597 CarbonylContact O-C 3.15Å; Y594-Q597 PolarHBondContact O-N 3.19Å; A595-Q597 PolarHBondContact O-N 3.42Å; Q597-R599 HydrophobicContact CB-CG 4.16Å; Q597-R599 PolarHBondContact O-N 3.3Å
598N94.5Very high97.2Very high118 Ų11849 Ų4963%0.63124%0.236SC*.THydrogen-bonded Turntrans60.120.1-170.7-55.6-65.8000115.2Y594 A595 D596 H600Y594-N598 PolarHBondContact O-N 2.89Å; A595-N598 PolarHBondContact O-N 2.95Å; D596-N598 VanDerWaalsContact C-N 3.35Å; N598-H600 VanDerWaalsContact C-N 3.29Å; N598-H600 PolarHBondContact O-N 3.37Å
599R96.6Very high97.2Very high79 Ų7950.7 Ų50.730%0.29825%0.247SC..  trans-84.270.2173.9-69.4168.861.6-173.1-2.4110.4E570 Y594 Q597 V601 D602 A603E570-R599 IonicContact OE1-NH1 2.85Å; E570-R599 IonicContact OE1-NH2 3.12Å; E570-R599 IonicContact OE2-CZ 2.84Å; E570-R599 IonicContact OE2-NH1 3.89Å; E570-R599 PolarHBondContact OE2-NH1 3.44Å; Y594-R599 VanDerWaalsContact CE1-NH1 3.32Å; Y594-R599 WeakPolarHBondContact O-CA 3.27Å; Y594-R599 PolarHBondContact O-N 3.41Å; Q597-R599 HydrophobicContact CB-CG 4.16Å; Q597-R599 PolarHBondContact O-N 3.3Å; R599-V601 PolarHBondContact O-N 2.83Å; R599-D602 HydrophobicContact CB-CB 4.22Å; R599-D602 IonicContact CZ-OD2 3.7Å; R599-D602 VanDerWaalsContact CZ-OD2 3.24Å; R599-D602 IonicContact NE-OD2 3.9Å; R599-D602 PolarHBondContact NE-OD2 3.3Å; R599-D602 IonicContact NH2-OD2 3.72Å; R599-D602 PolarHBondContact NH2-OD2 2.64Å; R599-D602 PolarHBondContact O-N 3Å; R599-A603 PolarHBondContact O-N 3.31Å
600H95.8Very high97.2Very high69 Ų6949.9 Ų49.932%0.31924%0.243SC..Hα-helixtrans-61.4-38-168.7-54.8-40.3000114.4N598 A603 L604 L627 T631N598-H600 VanDerWaalsContact C-N 3.29Å; N598-H600 PolarHBondContact O-N 3.37Å; H600-A603 PolarHBondContact O-N 3.5Å; H600-L604 WeakPolarHBondContact O-CG 3.43Å; H600-L604 PolarHBondContact O-N 3.06Å; H600-L627 HydrophobicContact CB-CD1 4.27Å; H600-L627 HydrophobicContact CB-CD2 4.23Å; H600-L627 WeakPolarHBondContact ND1-CD1 3.34Å; H600-T631 HydrophobicContact CB-CG2 4.39Å
601V96Very high97.1Very high102 Ų10250 Ų5062%0.61824%0.244SC*.Hα-helixtrans-65.7-44.6178.8178.30000110.9R599 A603 L604 N605R599-V601 PolarHBondContact O-N 2.83Å; V601-A603 VanDerWaalsContact C-N 3.33Å; V601-A603 PolarHBondContact O-N 2.85Å; V601-L604 PolarHBondContact O-N 3.42Å; V601-N605 PolarHBondContact O-N 3.2Å; V601-N605 PolarHBondContact O-ND2 3.41Å
602D97.3Very high97.1Very high55 Ų5556.4 Ų56.429%0.29428%0.275SS..Hα-helixtrans-65.4-39.6178.2-62.1-29000111.1Y594 R599 L604 N605 A606Y594-D602 HydrophobicContact CD1-CB 4.21Å; Y594-D602 VanDerWaalsContact CD2-C 3.49Å; Y594-D602 HydrophobicContact CD2-CB 3.47Å; Y594-D602 VanDerWaalsContact CD2-CB 3.47Å; Y594-D602 HydrophobicContact CE2-CB 3.79Å; Y594-D602 HydrophobicContact CG-CB 3.68Å; R599-D602 HydrophobicContact CB-CB 4.22Å; R599-D602 IonicContact CZ-OD2 3.7Å; R599-D602 VanDerWaalsContact CZ-OD2 3.24Å; R599-D602 IonicContact NE-OD2 3.9Å; R599-D602 PolarHBondContact NE-OD2 3.3Å; R599-D602 IonicContact NH2-OD2 3.72Å; R599-D602 PolarHBondContact NH2-OD2 2.64Å; R599-D602 PolarHBondContact O-N 3Å; D602-L604 PolarHBondContact O-N 2.79Å; D602-N605 PolarHBondContact O-N 3.19Å; D602-A606 WeakPolarHBondContact O-CB 3.5Å; D602-A606 PolarHBondContact O-N 3.24Å
603A98.1Very high97Very high0 Ų054.4 Ų54.40%027%0.273CS..Hα-helixtrans-59.2-47175.100000112.3G591 A595 R599 H600 V601 A606 W607 L627G591-A603 WeakPolarHBondContact O-CB 3.38Å; A595-A603 HydrophobicContact CB-CB 4.23Å; R599-A603 PolarHBondContact O-N 3.31Å; H600-A603 PolarHBondContact O-N 3.5Å; V601-A603 VanDerWaalsContact C-N 3.33Å; V601-A603 PolarHBondContact O-N 2.85Å; A603-A606 PolarHBondContact O-N 3.48Å; A603-W607 HydrophobicContact CB-CE3 4.48Å; A603-W607 HydrophobicContact CB-CH2 4.31Å; A603-W607 HydrophobicContact CB-CZ3 4.21Å; A603-W607 PolarHBondContact O-N 3.42Å; A603-L627 HydrophobicContact CB-CD2 3.81Å
604L97.5Very high96.9Very high27 Ų2758 Ų5814%0.14129%0.288CS..Hα-helixtrans-61.9-43.8176.2-71.3172.7000111.8H600 V601 D602 W607 R608 M624 L627 L628H600-L604 WeakPolarHBondContact O-CG 3.43Å; H600-L604 PolarHBondContact O-N 3.06Å; V601-L604 PolarHBondContact O-N 3.42Å; D602-L604 PolarHBondContact O-N 2.79Å; L604-W607 PolarHBondContact O-N 3.35Å; L604-R608 VanDerWaalsContact O-CB 3.25Å; L604-R608 WeakPolarHBondContact O-CB 3.49Å; L604-R608 PolarHBondContact O-N 2.73Å; L604-M624 HydrophobicContact CD2-CB 3.94Å; L604-M624 HydrophobicContact CD2-CG 3.89Å; L604-L627 HydrophobicContact CD2-CD2 4.01Å; L604-L627 HydrophobicContact CG-CD2 3.89Å; L604-L628 HydrophobicContact CD1-CD2 3.7Å; L604-L628 HydrophobicContact CD1-CG 4.21Å; L604-L628 HydrophobicContact CD2-CD1 4.24Å; L604-L628 HydrophobicContact CD2-CD2 4.41Å; L604-L628 HydrophobicContact CD2-CG 3.99Å
605N97.8Very high96.8Very high83 Ų8360.5 Ų60.544%0.44431%0.306SS..Hα-helixtrans-63-42.7178.1-72.5-27.8000111.8V601 D602 R608 N609V601-N605 PolarHBondContact O-N 3.2Å; V601-N605 PolarHBondContact O-ND2 3.41Å; D602-N605 PolarHBondContact O-N 3.19Å; N605-R608 PolarHBondContact O-N 2.87Å; N605-N609 PolarHBondContact O-N 3.15Å; N605-N609 PolarHBondContact O-ND2 3.41Å
606A98.1Very high96.7Very high4 Ų463.8 Ų63.83%0.03332%0.32CS..Hα-helixtrans-64.3-47.5177.200000111.8L590 Y594 D602 A603 R608 N609 A610L590-A606 HydrophobicContact CB-CB 4.43Å; L590-A606 HydrophobicContact CD2-CB 4.42Å; L590-A606 HydrophobicContact CG-CB 4.42Å; Y594-A606 HydrophobicContact CD2-CB 4.22Å; Y594-A606 HydrophobicContact CE2-CB 4.4Å; D602-A606 WeakPolarHBondContact O-CB 3.5Å; D602-A606 PolarHBondContact O-N 3.24Å; A603-A606 PolarHBondContact O-N 3.48Å; A606-R608 VanDerWaalsContact C-N 3.32Å; A606-R608 PolarHBondContact O-N 2.95Å; A606-N609 WeakPolarHBondContact O-CB 3.36Å; A606-N609 PolarHBondContact O-N 2.87Å; A606-A610 PolarHBondContact O-N 3.18Å
607W98.5Very high96.8Very high8 Ų860.4 Ų60.43%0.0330%0.302CS..Hα-helixtrans-65.1-34.4176.2-68.6-30.8000113.2Y588 G591 R592 A595 A603 L604 A610 T611 A620 N623 M624 L627Y588-W607 AromaticContact CD2-CD1 3.93Å; Y588-W607 AromaticContact CD2-NE1 3.84Å; Y588-W607 PolarHBondContact O-NE1 3.17Å; G591-W607 VanDerWaalsContact C-CZ2 3.48Å; G591-W607 WeakPolarHBondContact O-CZ2 3.13Å; R592-W607 HydrophobicContact CG-CZ2 4.28Å; A595-W607 HydrophobicContact CB-CH2 3.82Å; A595-W607 HydrophobicContact CB-CZ2 4.19Å; A603-W607 HydrophobicContact CB-CE3 4.48Å; A603-W607 HydrophobicContact CB-CH2 4.31Å; A603-W607 HydrophobicContact CB-CZ3 4.21Å; A603-W607 PolarHBondContact O-N 3.42Å; L604-W607 PolarHBondContact O-N 3.35Å; W607-A610 WeakPolarHBondContact O-CB 3.25Å; W607-A610 PolarHBondContact O-N 3.43Å; W607-T611 WeakPolarHBondContact O-CG2 3.44Å; W607-T611 PolarHBondContact O-N 3.44Å; W607-T611 PolarHBondContact O-OG1 2.9Å; W607-A620 HydrophobicContact CB-CB 4.26Å; W607-A620 HydrophobicContact CG-CB 4.46Å; W607-N623 HydrophobicContact CD2-CB 3.88Å; W607-N623 HydrophobicContact CE3-CB 3.85Å; W607-N623 HydrophobicContact CH2-CB 3.7Å; W607-N623 HydrophobicContact CZ2-CB 3.73Å; W607-N623 HydrophobicContact CZ3-CB 3.75Å; W607-N623 WeakPolarHBondContact CZ3-O 3.46Å; W607-M624 HydrophobicContact CB-CG 3.5Å; W607-M624 HydrophobicContact CB-SD 3.85Å; W607-M624 HydrophobicContact CD2-CG 4.34Å; W607-M624 HydrophobicContact CE3-CG 3.81Å; W607-M624 HydrophobicContact CG-CG 4.28Å; W607-L627 HydrophobicContact CE3-CD2 4.36Å; W607-L627 HydrophobicContact CH2-CD2 4.27Å; W607-L627 HydrophobicContact CZ3-CB 3.89Å; W607-L627 HydrophobicContact CZ3-CD2 3.55Å; W607-L627 HydrophobicContact CZ3-CG 4.33Å
608R97.9Very high96.8Very high154 Ų15459.4 Ų59.458%0.58130%0.3SS*.Hα-helixtrans-63.1-41.3172.4-169.2178-166.6174.45.2111.8L604 N605 A606 A610 T611 M612 M624L604-R608 VanDerWaalsContact O-CB 3.25Å; L604-R608 WeakPolarHBondContact O-CB 3.49Å; L604-R608 PolarHBondContact O-N 2.73Å; N605-R608 PolarHBondContact O-N 2.87Å; A606-R608 VanDerWaalsContact C-N 3.32Å; A606-R608 PolarHBondContact O-N 2.95Å; R608-A610 VanDerWaalsContact C-N 3.31Å; R608-A610 PolarHBondContact O-N 3.03Å; R608-T611 PolarHBondContact O-N 3.3Å; R608-T611 PolarHBondContact O-OG1 2.97Å; R608-T611 VanDerWaalsContact O-OG1 3.1Å; R608-M612 HydrophobicContact CG-SD 4.43Å; R608-M612 WeakPolarHBondContact O-CB 3.23Å; R608-M612 VanDerWaalsContact O-CG 3.28Å; R608-M612 WeakPolarHBondContact O-CG 3.36Å; R608-M612 PolarHBondContact O-N 3.25Å; R608-M624 HydrophobicContact CB-SD 4.28Å
609N97.7Very high97Very high65 Ų6558.2 Ų58.235%0.34829%0.293SS..Hα-helixtrans-62.1-40.4173.2-72.7-26.5000111.5Y587 N605 A606 M612 L613Y587-N609 HydrophobicContact CD1-CB 3.77Å; Y587-N609 HydrophobicContact CD2-CB 4.13Å; Y587-N609 HydrophobicContact CE1-CB 3.99Å; Y587-N609 HydrophobicContact CE2-CB 4.32Å; Y587-N609 HydrophobicContact CG-CB 3.85Å; N605-N609 PolarHBondContact O-N 3.15Å; N605-N609 PolarHBondContact O-ND2 3.41Å; A606-N609 WeakPolarHBondContact O-CB 3.36Å; A606-N609 PolarHBondContact O-N 2.87Å; N609-M612 PolarHBondContact O-N 2.88Å; N609-L613 WeakPolarHBondContact O-CG 3.36Å; N609-L613 PolarHBondContact O-N 3.04Å; N609-L613 VanDerWaalsContact O-N 3.08Å
610A97.9Very high97Very high0 Ų054.4 Ų54.40%028%0.279CS..Hα-helixtrans-60.2-46.5175.500000111.8P584 A606 W607 R608 L613 K614 A620P584-A610 WeakPolarHBondContact O-CB 3.39Å; A606-A610 PolarHBondContact O-N 3.18Å; W607-A610 WeakPolarHBondContact O-CB 3.25Å; W607-A610 PolarHBondContact O-N 3.43Å; R608-A610 VanDerWaalsContact C-N 3.31Å; R608-A610 PolarHBondContact O-N 3.03Å; A610-L613 PolarHBondContact O-N 3.46Å; A610-K614 PolarHBondContact O-N 3.14Å; A610-A620 HydrophobicContact CB-CB 4.17Å
611T97.2Very high97.1Very high5 Ų552.2 Ų52.23%0.03127%0.267CS..Hα-helixtrans-73.8-29.4-179.861.80000113.3W607 R608 K614 P615 A620 W621 M624W607-T611 WeakPolarHBondContact O-CG2 3.44Å; W607-T611 PolarHBondContact O-N 3.44Å; W607-T611 PolarHBondContact O-OG1 2.9Å; R608-T611 PolarHBondContact O-N 3.3Å; R608-T611 PolarHBondContact O-OG1 2.97Å; R608-T611 VanDerWaalsContact O-OG1 3.1Å; T611-K614 WeakPolarHBondContact CA-O 3.45Å; T611-K614 CarbonylContact O-C 3.47Å; T611-K614 PolarHBondContact O-N 2.84Å; T611-P615 WeakPolarHBondContact O-CA 3.33Å; T611-A620 HydrophobicContact CG2-CB 3.69Å; T611-W621 HydrophobicContact CG2-CD2 3.63Å; T611-W621 VanDerWaalsContact CG2-CE2 3.48Å; T611-W621 HydrophobicContact CG2-CE3 4.32Å; T611-W621 HydrophobicContact CG2-CG 3.76Å; T611-W621 HydrophobicContact CG2-CZ2 4.05Å; T611-M624 HydrophobicContact CG2-CE 3.77Å
612M96.8Very high97.2Very high134 Ų13448.2 Ų48.266%0.6624%0.243SC*.Hα-helixtrans-64.7-39.6171-78.4-179.562.900112.1R608 N609R608-M612 HydrophobicContact CG-SD 4.43Å; R608-M612 WeakPolarHBondContact O-CB 3.23Å; R608-M612 VanDerWaalsContact O-CG 3.28Å; R608-M612 WeakPolarHBondContact O-CG 3.36Å; R608-M612 PolarHBondContact O-N 3.25Å; N609-M612 PolarHBondContact O-N 2.88Å
613L96.1Very high97.2Very high71 Ų7147.3 Ų47.337%0.37224%0.238SC..Hα-helixtrans-77.6-32.2177.1-67.2175.1000112.5K582 P584 Y587 N609 A610K582-L613 HydrophobicContact CG-CD2 4.24Å; P584-L613 HydrophobicContact CB-CB 4.34Å; P584-L613 HydrophobicContact CG-CB 3.79Å; Y587-L613 HydrophobicContact CD2-CD1 3.71Å; Y587-L613 HydrophobicContact CE2-CD1 3.72Å; N609-L613 WeakPolarHBondContact O-CG 3.36Å; N609-L613 PolarHBondContact O-N 3.04Å; N609-L613 VanDerWaalsContact O-N 3.08Å; A610-L613 PolarHBondContact O-N 3.46Å
614K96.7Very high97.2Very high75 Ų7547.5 Ų47.533%0.32624%0.239SC..  trans-137.188.8-179.9-174.2177.1178.6-177.80110.1P584 A610 T611 D616 H617P584-K614 HydrophobicContact CB-CB 3.69Å; P584-K614 HydrophobicContact CB-CD 4.44Å; P584-K614 HydrophobicContact CG-CB 3.69Å; A610-K614 PolarHBondContact O-N 3.14Å; T611-K614 WeakPolarHBondContact CA-O 3.45Å; T611-K614 CarbonylContact O-C 3.47Å; T611-K614 PolarHBondContact O-N 2.84Å; K614-D616 VanDerWaalsContact CE-OD1 3.31Å; K614-D616 WeakPolarHBondContact CE-OD1 3.27Å; K614-D616 WeakPolarHBondContact CE-OD2 3.28Å; K614-D616 WeakPolarHBondContact CG-OD1 3.39Å; K614-D616 PolarHBondContact O-N 3.33Å; K614-D616 VanDerWaalsContact O-N 3.14Å; K614-H617 HydrophobicContact CB-CB 4.11Å; K614-H617 HydrophobicContact CD-CB 4.17Å; K614-H617 HydrophobicContact CG-CB 4.03Å; K614-H617 WeakPolarHBondContact O-CB 3.37Å; K614-H617 PolarHBondContact O-N 3.45Å
615P96.1Very high97.2Very high65 Ų6546.2 Ų46.242%0.42223%0.232SC..THydrogen-bonded Turntrans-58.9-26.4-176.7-28.537000114.6T611 H617 W621 L647T611-P615 WeakPolarHBondContact O-CA 3.33Å; P615-H617 VanDerWaalsContact C-N 3.29Å; P615-H617 PolarHBondContact O-N 3.33Å; P615-W621 PolarHBondContact O-NE1 3.36Å; P615-L647 HydrophobicContact CB-CD1 4.15Å
616D94.6Very high97.2Very high95 Ų9545.2 Ų45.251%0.50823%0.226SC..THydrogen-bonded Turntrans-85.59.9176.765.7-42000113.9K614 S618 L648K614-D616 VanDerWaalsContact CE-OD1 3.31Å; K614-D616 WeakPolarHBondContact CE-OD1 3.27Å; K614-D616 WeakPolarHBondContact CE-OD2 3.28Å; K614-D616 WeakPolarHBondContact CG-OD1 3.39Å; K614-D616 PolarHBondContact O-N 3.33Å; K614-D616 VanDerWaalsContact O-N 3.14Å; D616-S618 VanDerWaalsContact C-N 3.27Å; D616-S618 PolarHBondContact O-N 3Å; D616-L648 HydrophobicContact CB-CD2 4.07Å
617H96.4Very high97.1Very high13 Ų1345.8 Ų45.86%0.0623%0.228CC..  trans-7574.2178.8-163.1-47.6000112.4D585 Y588 K614 P615 L619 A620 W621D585-H617 IonicContact OD1-CD2 2.86Å; D585-H617 IonicContact OD1-NE2 3.97Å; Y588-H617 AromaticContact CD2-CE1 3.53Å; Y588-H617 AromaticContact CG-CE1 3.55Å; Y588-H617 AromaticContact CG-NE2 3.77Å; K614-H617 HydrophobicContact CB-CB 4.11Å; K614-H617 HydrophobicContact CD-CB 4.17Å; K614-H617 HydrophobicContact CG-CB 4.03Å; K614-H617 WeakPolarHBondContact O-CB 3.37Å; K614-H617 PolarHBondContact O-N 3.45Å; P615-H617 VanDerWaalsContact C-N 3.29Å; P615-H617 PolarHBondContact O-N 3.33Å; H617-L619 PolarHBondContact O-N 3.2Å; H617-A620 HydrophobicContact CB-CB 4.39Å; H617-A620 WeakPolarHBondContact ND1-CB 3.39Å; H617-A620 PolarHBondContact ND1-N 2.97Å; H617-A620 PolarHBondContact O-N 3.46Å; H617-W621 PolarHBondContact O-N 3.48Å
618S95.9Very high97.1Very high26 Ų2645.5 Ų45.518%0.18223%0.227CC..Hα-helixtrans-45.5-50-177.6168.30000114.6D616 A620 W621 N622 D651D616-S618 VanDerWaalsContact C-N 3.27Å; D616-S618 PolarHBondContact O-N 3Å; S618-A620 VanDerWaalsContact C-N 3.26Å; S618-A620 PolarHBondContact O-N 3.14Å; S618-W621 WeakPolarHBondContact O-CB 3.39Å; S618-W621 PolarHBondContact O-N 2.87Å; S618-N622 WeakPolarHBondContact O-CB 3.48Å; S618-N622 PolarHBondContact O-N 3.09Å; S618-D651 WeakPolarHBondContact CB-OD2 3.35Å; S618-D651 PolarHBondContact OG-OD2 3.46Å
619L97.1Very high96.9Very high92 Ų9239.2 Ų39.248%0.48221%0.205SC..Hα-helixtrans-61.1-32.3-176.8-64.7175.5000113.5Y588 H617 N623Y588-L619 HydrophobicContact CD2-CB 4.45Å; Y588-L619 HydrophobicContact CE2-CB 3.68Å; H617-L619 PolarHBondContact O-N 3.2Å; L619-N623 VanDerWaalsContact O-CB 3.28Å; L619-N623 WeakPolarHBondContact O-CB 3.22Å; L619-N623 PolarHBondContact O-N 3.3Å; L619-N623 PolarHBondContact O-OD1 2.9Å
620A97.4Very high96.7Very high0 Ų041.8 Ų41.80%022%0.219CC..Hα-helixtrans-75.2-43.1179.900000110.3Y588 W607 A610 T611 H617 S618 N623 M624Y588-A620 HydrophobicContact CD2-CB 3.99Å; W607-A620 HydrophobicContact CB-CB 4.26Å; W607-A620 HydrophobicContact CG-CB 4.46Å; A610-A620 HydrophobicContact CB-CB 4.17Å; T611-A620 HydrophobicContact CG2-CB 3.69Å; H617-A620 HydrophobicContact CB-CB 4.39Å; H617-A620 WeakPolarHBondContact ND1-CB 3.39Å; H617-A620 PolarHBondContact ND1-N 2.97Å; H617-A620 PolarHBondContact O-N 3.46Å; S618-A620 VanDerWaalsContact C-N 3.26Å; S618-A620 PolarHBondContact O-N 3.14Å; A620-N623 PolarHBondContact O-N 3Å; A620-M624 WeakPolarHBondContact O-CG 3.31Å; A620-M624 PolarHBondContact O-N 3.44Å
621W98Very high96.5Very high22 Ų2245 Ų458%0.08324%0.239CC..Hα-helixtrans-57-50.7171.5-74.6117.8000111.9T611 P615 H617 S618 N623 M624 V625 I640 A644 L647 I654T611-W621 HydrophobicContact CG2-CD2 3.63Å; T611-W621 VanDerWaalsContact CG2-CE2 3.48Å; T611-W621 HydrophobicContact CG2-CE3 4.32Å; T611-W621 HydrophobicContact CG2-CG 3.76Å; T611-W621 HydrophobicContact CG2-CZ2 4.05Å; P615-W621 PolarHBondContact O-NE1 3.36Å; H617-W621 PolarHBondContact O-N 3.48Å; S618-W621 WeakPolarHBondContact O-CB 3.39Å; S618-W621 PolarHBondContact O-N 2.87Å; W621-N623 VanDerWaalsContact C-N 3.35Å; W621-N623 PolarHBondContact O-N 3.46Å; W621-M624 HydrophobicContact CD2-CE 3.88Å; W621-M624 HydrophobicContact CE3-CE 3.29Å; W621-M624 HydrophobicContact CG-CE 4.47Å; W621-M624 HydrophobicContact CZ3-CE 3.69Å; W621-M624 PolarHBondContact O-N 3.1Å; W621-V625 WeakPolarHBondContact O-CG2 3.32Å; W621-V625 PolarHBondContact O-N 3.49Å; W621-V625 VanDerWaalsContact O-N 3.14Å; W621-I640 HydrophobicContact CE3-CG2 3.75Å; W621-I640 HydrophobicContact CZ3-CG2 3.89Å; W621-A644 HydrophobicContact CB-CB 3.77Å; W621-A644 HydrophobicContact CD2-CB 3.54Å; W621-A644 HydrophobicContact CE3-CB 3.65Å; W621-A644 HydrophobicContact CG-CB 3.61Å; W621-A644 HydrophobicContact CZ3-CB 4.43Å; W621-L647 HydrophobicContact CZ2-CD1 3.86Å; W621-I654 HydrophobicContact CB-CD1 3.76Å; W621-I654 HydrophobicContact CB-CG1 4.41Å; W621-I654 HydrophobicContact CG-CD1 4.49Å
622N97.6Very high96.3Very high19 Ų1947.2 Ų47.210%0.10226%0.263CS..Hα-helixtrans-61.2-43.6-179.1-172.756.6000111.8S618 M624 V625 I626 T653 I654 S657S618-N622 WeakPolarHBondContact O-CB 3.48Å; S618-N622 PolarHBondContact O-N 3.09Å; N622-M624 PolarHBondContact O-N 3.2Å; N622-V625 PolarHBondContact O-N 2.91Å; N622-I626 VanDerWaalsContact ND2-CD1 3.35Å; N622-I626 WeakPolarHBondContact ND2-CD1 3.49Å; N622-I626 WeakPolarHBondContact O-CG1 3.48Å; N622-I626 PolarHBondContact O-N 2.83Å; N622-T653 PolarHBondContact OD1-O 3.09Å; N622-I654 HydrophobicContact CB-CG1 4.09Å; N622-S657 WeakPolarHBondContact OD1-CB 3.44Å; N622-S657 PolarHBondContact OD1-OG 2.68Å
623N98.1Very high96.3Very high35 Ų3544.2 Ų44.219%0.18725%0.25CC..Hα-helixtrans-63.5-37.3177.5-78.76.1000112.9Y588 W607 L619 A620 W621 I626 L627Y588-N623 WeakPolarHBondContact CE2-ND2 3.35Å; W607-N623 HydrophobicContact CD2-CB 3.88Å; W607-N623 HydrophobicContact CE3-CB 3.85Å; W607-N623 HydrophobicContact CH2-CB 3.7Å; W607-N623 HydrophobicContact CZ2-CB 3.73Å; W607-N623 HydrophobicContact CZ3-CB 3.75Å; W607-N623 WeakPolarHBondContact CZ3-O 3.46Å; L619-N623 VanDerWaalsContact O-CB 3.28Å; L619-N623 WeakPolarHBondContact O-CB 3.22Å; L619-N623 PolarHBondContact O-N 3.3Å; L619-N623 PolarHBondContact O-OD1 2.9Å; A620-N623 PolarHBondContact O-N 3Å; W621-N623 VanDerWaalsContact C-N 3.35Å; W621-N623 PolarHBondContact O-N 3.46Å; N623-I626 PolarHBondContact O-N 2.64Å; N623-L627 VanDerWaalsContact O-CB 3.26Å; N623-L627 WeakPolarHBondContact O-CB 3.43Å; N623-L627 PolarHBondContact O-N 3.2Å
624M98.1Very high96.3Very high4 Ų442.6 Ų42.62%0.0224%0.241CC..Hα-helixtrans-62.5-44.5173.6-71.5-174-69.600111.9L604 W607 R608 T611 A620 W621 N622 L627 L628 I640L604-M624 HydrophobicContact CD2-CB 3.94Å; L604-M624 HydrophobicContact CD2-CG 3.89Å; W607-M624 HydrophobicContact CB-CG 3.5Å; W607-M624 HydrophobicContact CB-SD 3.85Å; W607-M624 HydrophobicContact CD2-CG 4.34Å; W607-M624 HydrophobicContact CE3-CG 3.81Å; W607-M624 HydrophobicContact CG-CG 4.28Å; R608-M624 HydrophobicContact CB-SD 4.28Å; T611-M624 HydrophobicContact CG2-CE 3.77Å; A620-M624 WeakPolarHBondContact O-CG 3.31Å; A620-M624 PolarHBondContact O-N 3.44Å; W621-M624 HydrophobicContact CD2-CE 3.88Å; W621-M624 HydrophobicContact CE3-CE 3.29Å; W621-M624 HydrophobicContact CG-CE 4.47Å; W621-M624 HydrophobicContact CZ3-CE 3.69Å; W621-M624 PolarHBondContact O-N 3.1Å; N622-M624 PolarHBondContact O-N 3.2Å; M624-L627 PolarHBondContact O-N 3.07Å; M624-L628 WeakPolarHBondContact O-CB 3.18Å; M624-L628 WeakPolarHBondContact O-CG 3.43Å; M624-L628 PolarHBondContact O-N 3.37Å; M624-I640 HydrophobicContact CB-CD1 4.5Å; M624-I640 HydrophobicContact CB-CG2 4.1Å; M624-I640 HydrophobicContact CE-CG2 4.25Å
625V97.8Very high96.2Very high0 Ų041.2 Ų41.20%025%0.249CC..Hα-helixtrans-62.4-47.2178176.70000110.7W621 N622 L627 L628 D629 I640 V661W621-V625 WeakPolarHBondContact O-CG2 3.32Å; W621-V625 PolarHBondContact O-N 3.49Å; W621-V625 VanDerWaalsContact O-N 3.14Å; N622-V625 PolarHBondContact O-N 2.91Å; V625-L627 PolarHBondContact O-N 3.29Å; V625-L628 PolarHBondContact O-N 3.35Å; V625-D629 WeakPolarHBondContact O-CB 3.48Å; V625-D629 PolarHBondContact O-N 3.3Å; V625-I640 HydrophobicContact CG2-CG2 4.04Å; V625-V661 HydrophobicContact CG1-CG2 4.06Å
626I96.9Very high96.2Very high63 Ų6341.9 Ų41.932%0.32325%0.246SC..Hα-helixtrans-61.8-44178.8-69.3170000111N622 N623 D629 N630N622-I626 VanDerWaalsContact ND2-CD1 3.35Å; N622-I626 WeakPolarHBondContact ND2-CD1 3.49Å; N622-I626 WeakPolarHBondContact O-CG1 3.48Å; N622-I626 PolarHBondContact O-N 2.83Å; N623-I626 PolarHBondContact O-N 2.64Å; I626-D629 PolarHBondContact O-N 2.9Å; I626-N630 WeakPolarHBondContact O-CB 3.35Å; I626-N630 VanDerWaalsContact O-CG 3.23Å; I626-N630 PolarHBondContact O-N 3.2Å; I626-N630 PolarHBondContact O-ND2 3.36Å
627L97Very high96.3Very high15 Ų1537.4 Ų37.48%0.07922%0.222CC..Hα-helixtrans-65-42.9-179.6179.761000112.1H600 A603 L604 W607 N623 M624 V625 D629 N630 T631H600-L627 HydrophobicContact CB-CD1 4.27Å; H600-L627 HydrophobicContact CB-CD2 4.23Å; H600-L627 WeakPolarHBondContact ND1-CD1 3.34Å; A603-L627 HydrophobicContact CB-CD2 3.81Å; L604-L627 HydrophobicContact CD2-CD2 4.01Å; L604-L627 HydrophobicContact CG-CD2 3.89Å; W607-L627 HydrophobicContact CE3-CD2 4.36Å; W607-L627 HydrophobicContact CH2-CD2 4.27Å; W607-L627 HydrophobicContact CZ3-CB 3.89Å; W607-L627 HydrophobicContact CZ3-CD2 3.55Å; W607-L627 HydrophobicContact CZ3-CG 4.33Å; N623-L627 VanDerWaalsContact O-CB 3.26Å; N623-L627 WeakPolarHBondContact O-CB 3.43Å; N623-L627 PolarHBondContact O-N 3.2Å; M624-L627 PolarHBondContact O-N 3.07Å; V625-L627 PolarHBondContact O-N 3.29Å; L627-D629 VanDerWaalsContact C-N 3.33Å; L627-N630 PolarHBondContact O-N 2.89Å; L627-T631 HydrophobicContact CD1-CG2 4.27Å; L627-T631 WeakPolarHBondContact O-CB 3.36Å; L627-T631 WeakPolarHBondContact O-CG2 3.37Å; L627-T631 PolarHBondContact O-N 3.17Å; L627-T631 PolarHBondContact O-OG1 3.02Å
628L96.8Very high96.3Very high2 Ų238 Ų381%0.0123%0.225CC..Hα-helixtrans-67-35.1175.8-72.1166.7000112.3L604 M624 V625 T631 G632 N633 Q636 A637 I640L604-L628 HydrophobicContact CD1-CD2 3.7Å; L604-L628 HydrophobicContact CD1-CG 4.21Å; L604-L628 HydrophobicContact CD2-CD1 4.24Å; L604-L628 HydrophobicContact CD2-CD2 4.41Å; L604-L628 HydrophobicContact CD2-CG 3.99Å; M624-L628 WeakPolarHBondContact O-CB 3.18Å; M624-L628 WeakPolarHBondContact O-CG 3.43Å; M624-L628 PolarHBondContact O-N 3.37Å; V625-L628 PolarHBondContact O-N 3.35Å; L628-T631 WeakPolarHBondContact CA-OG1 3.49Å; L628-T631 PolarHBondContact O-OG1 3.21Å; L628-G632 PolarHBondContact O-N 3.17Å; L628-N633 HydrophobicContact CD2-CB 3.93Å; L628-N633 PolarHBondContact O-N 3.01Å; L628-Q636 HydrophobicContact CD1-CB 4.11Å; L628-Q636 HydrophobicContact CD1-CG 3.78Å; L628-Q636 HydrophobicContact CD2-CB 4.22Å; L628-Q636 HydrophobicContact CD2-CG 4.21Å; L628-A637 HydrophobicContact CB-CB 3.6Å; L628-I640 HydrophobicContact CD1-CD1 3.5Å; L628-I640 VanDerWaalsContact CD1-CD1 3.5Å; L628-I640 HydrophobicContact CD1-CG1 4.28Å
629D95.3Very high96.4Very high22 Ų2241.5 Ų41.512%0.11824%0.241CC..Hα-helixtrans-63.9-46.6173.4-173.531.7000111.6V625 I626 L627 T631 G632 L634 V661 K664V625-D629 WeakPolarHBondContact O-CB 3.48Å; V625-D629 PolarHBondContact O-N 3.3Å; I626-D629 PolarHBondContact O-N 2.9Å; L627-D629 VanDerWaalsContact C-N 3.33Å; D629-T631 VanDerWaalsContact C-N 3.32Å; D629-T631 PolarHBondContact O-N 3.3Å; D629-G632 PolarHBondContact O-N 3.41Å; D629-G632 VanDerWaalsContact O-N 3.16Å; D629-L634 WeakPolarHBondContact OD1-CD2 3.31Å; D629-V661 HydrophobicContact CB-CG2 3.82Å; D629-K664 WeakPolarHBondContact OD1-CD 3.48Å; D629-K664 WeakPolarHBondContact OD1-CE 3.49Å; D629-K664 IonicContact OD1-NZ 3.29Å; D629-K664 PolarHBondContact OD1-NZ 3.4Å; D629-K664 IonicContact OD2-NZ 2.82Å; D629-K664 PolarHBondContact OD2-NZ 2.94Å
630N93.8Very high96.4Very high119 Ų11938 Ų3864%0.63622%0.223SC*.Hα-helixtrans-67.2-31.7179.5-71.1-14000112.8I626 L627 G632I626-N630 WeakPolarHBondContact O-CB 3.35Å; I626-N630 VanDerWaalsContact O-CG 3.23Å; I626-N630 PolarHBondContact O-N 3.2Å; I626-N630 PolarHBondContact O-ND2 3.36Å; L627-N630 PolarHBondContact O-N 2.89Å; N630-G632 VanDerWaalsContact C-N 3.28Å
631T93.3Very high96.3Very high67 Ų6738 Ų3841%0.41122%0.223SC..THydrogen-bonded Turntrans-850.417652.80000113.2H600 L627 L628 D629 N633H600-T631 HydrophobicContact CB-CG2 4.39Å; L627-T631 HydrophobicContact CD1-CG2 4.27Å; L627-T631 WeakPolarHBondContact O-CB 3.36Å; L627-T631 WeakPolarHBondContact O-CG2 3.37Å; L627-T631 PolarHBondContact O-N 3.17Å; L627-T631 PolarHBondContact O-OG1 3.02Å; L628-T631 WeakPolarHBondContact CA-OG1 3.49Å; L628-T631 PolarHBondContact O-OG1 3.21Å; D629-T631 VanDerWaalsContact C-N 3.32Å; D629-T631 PolarHBondContact O-N 3.3Å; T631-N633 VanDerWaalsContact C-N 3.28Å; T631-N633 PolarHBondContact O-N 3.11Å
632G93.1Very high96.3Very high53 Ų5340.6 Ų40.655%0.54623%0.232SC..THydrogen-bonded Turntrans78.43.8177.400000115L628 D629 N630 L634L628-G632 PolarHBondContact O-N 3.17Å; D629-G632 PolarHBondContact O-N 3.41Å; D629-G632 VanDerWaalsContact O-N 3.16Å; N630-G632 VanDerWaalsContact C-N 3.28Å; G632-L634 PolarHBondContact O-N 3.3Å
633N95.3Very high96.2Very high71 Ų7143.6 Ų43.638%0.3825%0.246SC..  trans-83.262.7177.7-166.5-11.9000111.1L628 T631 G635 Q636 A637L628-N633 HydrophobicContact CD2-CB 3.93Å; L628-N633 PolarHBondContact O-N 3.01Å; T631-N633 VanDerWaalsContact C-N 3.28Å; T631-N633 PolarHBondContact O-N 3.11Å; N633-G635 VanDerWaalsContact C-N 3.32Å; N633-G635 PolarHBondContact O-N 3.23Å; N633-Q636 PolarHBondContact ND2-OE1 3.1Å; N633-Q636 PolarHBondContact O-N 3.46Å; N633-Q636 WeakPolarHBondContact OD1-CB 3.15Å; N633-A637 PolarHBondContact O-N 2.91Å
634L95.9Very high96.1Very high36 Ų3641.9 Ų41.919%0.18824%0.237CC..Hα-helixtrans-63.3-34-170.4-59.2-179000113.3D629 G632 A637 E638 V661 K664 L665D629-L634 WeakPolarHBondContact OD1-CD2 3.31Å; G632-L634 PolarHBondContact O-N 3.3Å; L634-A637 PolarHBondContact O-N 3.32Å; L634-E638 PolarHBondContact O-N 2.85Å; L634-V661 HydrophobicContact CB-CG1 4.36Å; L634-V661 HydrophobicContact CD2-CG1 4.43Å; L634-V661 WeakPolarHBondContact O-CG1 3.46Å; L634-K664 HydrophobicContact CD1-CB 3.79Å; L634-K664 HydrophobicContact CD2-CB 4.36Å; L634-K664 HydrophobicContact CD2-CD 4.04Å; L634-L665 HydrophobicContact CB-CD1 4.28Å; L634-L665 HydrophobicContact CB-CD2 3.68Å; L634-L665 HydrophobicContact CB-CG 3.94Å; L634-L665 HydrophobicContact CD1-CD2 4.04Å; L634-L665 HydrophobicContact CD1-CG 4.28Å
635G95.3Very high96.1Very high47 Ų4742.6 Ų42.649%0.48524%0.241SC..Hα-helixtrans-65.2-43.3178.500000112.3N633 E638 L639N633-G635 VanDerWaalsContact C-N 3.32Å; N633-G635 PolarHBondContact O-N 3.23Å; G635-E638 PolarHBondContact O-N 3.48Å; G635-L639 PolarHBondContact O-N 3.4Å; G635-L639 VanDerWaalsContact O-N 3.15Å
636Q95.6Very high96Very high79 Ų7950.7 Ų50.737%0.36928%0.276SS..Hα-helixtrans-70.9-37.4175.5-167.2177.5-7.900111.5L628 N633 E638 L639 I640L628-Q636 HydrophobicContact CD1-CB 4.11Å; L628-Q636 HydrophobicContact CD1-CG 3.78Å; L628-Q636 HydrophobicContact CD2-CB 4.22Å; L628-Q636 HydrophobicContact CD2-CG 4.21Å; N633-Q636 PolarHBondContact ND2-OE1 3.1Å; N633-Q636 PolarHBondContact O-N 3.46Å; N633-Q636 WeakPolarHBondContact OD1-CB 3.15Å; Q636-E638 VanDerWaalsContact C-N 3.3Å; Q636-E638 PolarHBondContact O-N 3.08Å; Q636-L639 PolarHBondContact O-N 3.16Å; Q636-I640 HydrophobicContact CG-CD1 4.28Å; Q636-I640 HydrophobicContact CG-CG1 4.44Å; Q636-I640 WeakPolarHBondContact O-CG1 3.35Å; Q636-I640 PolarHBondContact O-N 3.33Å
637A97.1Very high95.9Very high0 Ų052.3 Ų52.30%028%0.284CS..Hα-helixtrans-58.8-42.4174.800000111.7L628 N633 L634 G641 V661L628-A637 HydrophobicContact CB-CB 3.6Å; N633-A637 PolarHBondContact O-N 2.91Å; L634-A637 PolarHBondContact O-N 3.32Å; A637-G641 PolarHBondContact O-N 3.38Å; A637-V661 HydrophobicContact CB-CB 4.5Å; A637-V661 HydrophobicContact CB-CG1 3.85Å; A637-V661 HydrophobicContact CB-CG2 3.81Å
638E97.6Very high95.8Very high25 Ų2553 Ų5312%0.11729%0.288CS..Hα-helixtrans-62.5-48.1175179.4-179.3-178.800111.6L634 G635 Q636 G641 R642 L658 V661 L662 L665 K667L634-E638 PolarHBondContact O-N 2.85Å; G635-E638 PolarHBondContact O-N 3.48Å; Q636-E638 VanDerWaalsContact C-N 3.3Å; Q636-E638 PolarHBondContact O-N 3.08Å; E638-G641 PolarHBondContact O-N 3.05Å; E638-R642 HydrophobicContact CG-CG 4.49Å; E638-R642 WeakPolarHBondContact O-CG 3.43Å; E638-R642 PolarHBondContact O-N 3.25Å; E638-R642 IonicContact OE1-CZ 3.57Å; E638-R642 VanDerWaalsContact OE1-CZ 3.31Å; E638-R642 IonicContact OE1-NE 3.4Å; E638-R642 PolarHBondContact OE1-NE 2.82Å; E638-R642 IonicContact OE1-NH2 3.45Å; E638-R642 PolarHBondContact OE1-NH2 3.48Å; E638-L658 HydrophobicContact CB-CD1 4.4Å; E638-L658 HydrophobicContact CG-CD1 4.28Å; E638-V661 HydrophobicContact CB-CG1 4.27Å; E638-L662 HydrophobicContact CG-CD2 3.94Å; E638-L665 HydrophobicContact CB-CD1 4.12Å; E638-L665 VanDerWaalsContact OE2-CD1 3.26Å; E638-L665 WeakPolarHBondContact OE2-CD1 3.25Å; E638-K667 IonicContact OE1-NZ 3.79Å; E638-K667 PolarHBondContact OE1-NZ 2.89Å; E638-K667 IonicContact OE2-NZ 2.67Å; E638-K667 PolarHBondContact OE2-NZ 3.26Å
639L97.1Very high95.6Very high100 Ų10056.5 Ų56.552%0.52431%0.311SS..Hα-helixtrans-58.3-52.3-179.5-179.266.6000111.1G635 Q636 G641 R642 E643G635-L639 PolarHBondContact O-N 3.4Å; G635-L639 VanDerWaalsContact O-N 3.15Å; Q636-L639 PolarHBondContact O-N 3.16Å; L639-G641 PolarHBondContact O-N 2.89Å; L639-R642 PolarHBondContact O-N 2.97Å; L639-E643 WeakPolarHBondContact O-CG 3.17Å; L639-E643 PolarHBondContact O-N 3.36Å
640I96.5Very high95.4Very high19 Ų1961.1 Ų61.110%0.09734%0.336CS..Hα-helixtrans-61.7-44.4-179.9-69.3-169.8000111W621 M624 V625 L628 Q636 R642 E643 A644W621-I640 HydrophobicContact CE3-CG2 3.75Å; W621-I640 HydrophobicContact CZ3-CG2 3.89Å; M624-I640 HydrophobicContact CB-CD1 4.5Å; M624-I640 HydrophobicContact CB-CG2 4.1Å; M624-I640 HydrophobicContact CE-CG2 4.25Å; V625-I640 HydrophobicContact CG2-CG2 4.04Å; L628-I640 HydrophobicContact CD1-CD1 3.5Å; L628-I640 VanDerWaalsContact CD1-CD1 3.5Å; L628-I640 HydrophobicContact CD1-CG1 4.28Å; Q636-I640 HydrophobicContact CG-CD1 4.28Å; Q636-I640 HydrophobicContact CG-CG1 4.44Å; Q636-I640 WeakPolarHBondContact O-CG1 3.35Å; Q636-I640 PolarHBondContact O-N 3.33Å; I640-R642 VanDerWaalsContact C-N 3.32Å; I640-R642 PolarHBondContact O-N 3.47Å; I640-E643 PolarHBondContact O-N 2.8Å; I640-A644 WeakPolarHBondContact O-CB 3.28Å; I640-A644 PolarHBondContact O-N 3.29Å
641G96.9Very high95.4Very high0 Ų056.9 Ų56.90%031%0.313CS..Hα-helixtrans-61.8-39.2178.600000112.6A637 E638 L639 A644 L645A637-G641 PolarHBondContact O-N 3.38Å; E638-G641 PolarHBondContact O-N 3.05Å; L639-G641 PolarHBondContact O-N 2.89Å; G641-A644 PolarHBondContact O-N 3.08Å; G641-L645 WeakPolarHBondContact O-CG 3.5Å; G641-L645 PolarHBondContact O-N 3.4Å
642R96.9Very high95.4Very high76 Ų7656.6 Ų56.629%0.28731%0.307SS..Hα-helixtrans-68.9-40.9175.5-71.6-177.8-172.5-82.42.8112.5E638 L639 I640 A644 L645 K646 L658 E670E638-R642 HydrophobicContact CG-CG 4.49Å; E638-R642 WeakPolarHBondContact O-CG 3.43Å; E638-R642 PolarHBondContact O-N 3.25Å; E638-R642 IonicContact OE1-CZ 3.57Å; E638-R642 VanDerWaalsContact OE1-CZ 3.31Å; E638-R642 IonicContact OE1-NE 3.4Å; E638-R642 PolarHBondContact OE1-NE 2.82Å; E638-R642 IonicContact OE1-NH2 3.45Å; E638-R642 PolarHBondContact OE1-NH2 3.48Å; L639-R642 PolarHBondContact O-N 2.97Å; I640-R642 VanDerWaalsContact C-N 3.32Å; I640-R642 PolarHBondContact O-N 3.47Å; R642-A644 VanDerWaalsContact C-N 3.34Å; R642-L645 PolarHBondContact O-N 3.32Å; R642-K646 WeakPolarHBondContact O-CG 3.47Å; R642-K646 PolarHBondContact O-N 3.18Å; R642-L658 HydrophobicContact CG-CD2 4.07Å; R642-E670 IonicContact CZ-OE2 2.76Å; R642-E670 IonicContact NH1-OE2 2.81Å; R642-E670 PolarHBondContact NH1-OE2 2.87Å; R642-E670 IonicContact NH2-OE1 3.24Å; R642-E670 IonicContact NH2-OE2 2.66Å; R642-E670 PolarHBondContact NH2-OE2 3.44Å
643E96.2Very high95.4Very high82 Ų8256.2 Ų56.238%0.38329%0.294SS..Hα-helixtrans-59.9-45.7173.9-74.4-177.1169.900111.4L639 I640 L645 K646 L647L639-E643 WeakPolarHBondContact O-CG 3.17Å; L639-E643 PolarHBondContact O-N 3.36Å; I640-E643 PolarHBondContact O-N 2.8Å; E643-L645 PolarHBondContact O-N 3.34Å; E643-K646 WeakPolarHBondContact O-CB 3.45Å; E643-K646 PolarHBondContact O-N 3.24Å; E643-L647 PolarHBondContact O-N 2.96Å
644A96.6Very high95.5Very high0 Ų052.8 Ų52.80%028%0.276CS..Hα-helixtrans-59.2-44.8177.100000111.9W621 I640 G641 R642 K646 L647 L648 I654W621-A644 HydrophobicContact CB-CB 3.77Å; W621-A644 HydrophobicContact CD2-CB 3.54Å; W621-A644 HydrophobicContact CE3-CB 3.65Å; W621-A644 HydrophobicContact CG-CB 3.61Å; W621-A644 HydrophobicContact CZ3-CB 4.43Å; I640-A644 WeakPolarHBondContact O-CB 3.28Å; I640-A644 PolarHBondContact O-N 3.29Å; G641-A644 PolarHBondContact O-N 3.08Å; R642-A644 VanDerWaalsContact C-N 3.34Å; A644-K646 VanDerWaalsContact C-N 3.32Å; A644-K646 PolarHBondContact O-N 3.48Å; A644-L647 PolarHBondContact O-N 3.34Å; A644-L647 VanDerWaalsContact O-N 3.11Å; A644-L648 WeakPolarHBondContact O-CB 3.49Å; A644-L648 PolarHBondContact O-N 3.18Å; A644-I654 HydrophobicContact CB-CD1 4.09Å; A644-I654 HydrophobicContact CB-CG2 3.96Å
645L96.3Very high95.5Very high19 Ų1951.2 Ų51.210%0.09927%0.267CS..Hα-helixtrans-72.7-18.5179-68.3178.6000114.3G641 R642 E643 L647 L648 P649 I654 M655 L658 F674G641-L645 WeakPolarHBondContact O-CG 3.5Å; G641-L645 PolarHBondContact O-N 3.4Å; R642-L645 PolarHBondContact O-N 3.32Å; E643-L645 PolarHBondContact O-N 3.34Å; L645-L647 VanDerWaalsContact C-N 3.27Å; L645-L648 WeakPolarHBondContact CD2-O 3.44Å; L645-L648 CarbonylContact O-C 3.42Å; L645-P649 WeakPolarHBondContact O-CA 3.41Å; L645-I654 HydrophobicContact CD1-CG2 4.48Å; L645-I654 HydrophobicContact CD2-CB 3.93Å; L645-I654 HydrophobicContact CD2-CG2 3.8Å; L645-I654 HydrophobicContact CG-CB 4.48Å; L645-I654 HydrophobicContact CG-CG2 3.8Å; L645-M655 HydrophobicContact CD1-CG 3.98Å; L645-M655 HydrophobicContact CD2-CE 4.49Å; L645-M655 HydrophobicContact CD2-CG 3.82Å; L645-L658 HydrophobicContact CD1-CD2 3.66Å; L645-F674 HydrophobicContact CD1-CD1 3.99Å; L645-F674 HydrophobicContact CD1-CE1 3.46Å; L645-F674 VanDerWaalsContact CD1-CE1 3.46Å; L645-F674 HydrophobicContact CD1-CZ 4.1Å
646K95.9Very high95.5Very high170 Ų17051.1 Ų51.174%0.73925%0.253SS*.Hα-helixtrans-65.6-35.3167.3-72.4174.1-176176.50111.3R642 E643 A644R642-K646 WeakPolarHBondContact O-CG 3.47Å; R642-K646 PolarHBondContact O-N 3.18Å; E643-K646 WeakPolarHBondContact O-CB 3.45Å; E643-K646 PolarHBondContact O-N 3.24Å; A644-K646 VanDerWaalsContact C-N 3.32Å; A644-K646 PolarHBondContact O-N 3.48Å
647L94.9Very high95.6Very high96 Ų9647.7 Ų47.750%0.50324%0.239SC..Hα-helixtrans-86.4-35.3179.3-61.5171.2000112P615 W621 E643 A644 L645 P649P615-L647 HydrophobicContact CB-CD1 4.15Å; W621-L647 HydrophobicContact CZ2-CD1 3.86Å; E643-L647 PolarHBondContact O-N 2.96Å; A644-L647 PolarHBondContact O-N 3.34Å; A644-L647 VanDerWaalsContact O-N 3.11Å; L645-L647 VanDerWaalsContact C-N 3.27Å; L647-P649 VanDerWaalsContact C-CD 3.49Å; L647-P649 WeakPolarHBondContact O-CD 3.41Å
648L95.6Very high95.6Very high31 Ų3147.7 Ų47.716%0.16224%0.239CC..  trans-124.868.6-174.3-64.9175.1000110.6D616 A644 L645 N650 D651 I654D616-L648 HydrophobicContact CB-CD2 4.07Å; A644-L648 WeakPolarHBondContact O-CB 3.49Å; A644-L648 PolarHBondContact O-N 3.18Å; L645-L648 WeakPolarHBondContact CD2-O 3.44Å; L645-L648 CarbonylContact O-C 3.42Å; L648-N650 PolarHBondContact O-N 3.15Å; L648-N650 VanDerWaalsContact O-N 3.11Å; L648-D651 HydrophobicContact CB-CB 4.01Å; L648-D651 PolarHBondContact O-N 3.46Å; L648-I654 HydrophobicContact CD1-CD1 3.93Å
649P92.7Very high95.6Very high74 Ų7446.5 Ų46.548%0.48123%0.233SC..THydrogen-bonded Turntrans-66.8-17.1-169.226.3-36.2000114.8L645 L647 M655L645-P649 WeakPolarHBondContact O-CA 3.41Å; L647-P649 VanDerWaalsContact C-CD 3.49Å; L647-P649 WeakPolarHBondContact O-CD 3.41Å; P649-M655 WeakPolarHBondContact O-CE 3.43Å
650N91.1Very high95.6Very high120 Ų12043.4 Ų43.464%0.64222%0.217SC*.THydrogen-bonded Turntrans-110.312.3-178.4-64-28.7000112.9L648 H652 I681L648-N650 PolarHBondContact O-N 3.15Å; L648-N650 VanDerWaalsContact O-N 3.11Å; N650-H652 PolarHBondContact O-N 3.46Å; N650-I681 WeakPolarHBondContact O-CD1 3.28Å
651D94Very high95.6Very high30 Ų3042.5 Ų42.516%0.1621%0.212CC..  trans-79.9101.8-179.7-165.8-59.1000111.8S618 L648 T653 I654 M655S618-D651 WeakPolarHBondContact CB-OD2 3.35Å; S618-D651 PolarHBondContact OG-OD2 3.46Å; L648-D651 HydrophobicContact CB-CB 4.01Å; L648-D651 PolarHBondContact O-N 3.46Å; D651-T653 PolarHBondContact O-N 2.86Å; D651-T653 WeakPolarHBondContact OD1-CA 3.24Å; D651-T653 WeakPolarHBondContact OD1-CB 3.35Å; D651-T653 PolarHBondContact OD1-N 3.25Å; D651-T653 PolarHBondContact OD1-OG1 2.74Å; D651-I654 HydrophobicContact CB-CB 4.36Å; D651-I654 HydrophobicContact CB-CD1 3.97Å; D651-I654 HydrophobicContact CB-CG1 4.29Å; D651-I654 PolarHBondContact O-N 3.22Å; D651-I654 PolarHBondContact OD1-N 3.44Å; D651-I654 VanDerWaalsContact OD1-N 3.07Å; D651-M655 VanDerWaalsContact O-CG 3.29Å; D651-M655 WeakPolarHBondContact O-CG 3.39Å; D651-M655 PolarHBondContact O-N 3.04Å; D651-M655 VanDerWaalsContact O-N 3.11Å
652H92.7Very high95.6Very high61 Ų6142.5 Ų42.528%0.28221%0.212SC..Hα-helixtrans-65.5-24.2-177.672.453.4000113.4N650 F656 A678 I681N650-H652 PolarHBondContact O-N 3.46Å; H652-F656 WeakPolarHBondContact O-CB 3.34Å; H652-F656 PolarHBondContact O-N 3.18Å; H652-A678 HydrophobicContact CB-CB 4.21Å; H652-I681 HydrophobicContact CB-CB 4.27Å; H652-I681 HydrophobicContact CB-CD1 4.19Å; H652-I681 HydrophobicContact CB-CG2 4.3Å
653T94.6Very high95.6Very high44 Ų4439 Ų3927%0.2720%0.2SC..Hα-helixtrans-75.1-43.5-177.463.90000110.5N622 D651 F656 S657N622-T653 PolarHBondContact OD1-O 3.09Å; D651-T653 PolarHBondContact O-N 2.86Å; D651-T653 WeakPolarHBondContact OD1-CA 3.24Å; D651-T653 WeakPolarHBondContact OD1-CB 3.35Å; D651-T653 PolarHBondContact OD1-N 3.25Å; D651-T653 PolarHBondContact OD1-OG1 2.74Å; T653-F656 PolarHBondContact O-N 2.86Å; T653-S657 PolarHBondContact O-N 3.02Å; T653-S657 PolarHBondContact O-OG 2.65Å
654I96Very high95.5Very high0 Ų039.1 Ų39.10%020%0.199CC..Hα-helixtrans-67.8-40.6175.7-59.7169.9000110W621 N622 A644 L645 L648 D651 F656 S657 L658W621-I654 HydrophobicContact CB-CD1 3.76Å; W621-I654 HydrophobicContact CB-CG1 4.41Å; W621-I654 HydrophobicContact CG-CD1 4.49Å; N622-I654 HydrophobicContact CB-CG1 4.09Å; A644-I654 HydrophobicContact CB-CD1 4.09Å; A644-I654 HydrophobicContact CB-CG2 3.96Å; L645-I654 HydrophobicContact CD1-CG2 4.48Å; L645-I654 HydrophobicContact CD2-CB 3.93Å; L645-I654 HydrophobicContact CD2-CG2 3.8Å; L645-I654 HydrophobicContact CG-CB 4.48Å; L645-I654 HydrophobicContact CG-CG2 3.8Å; L648-I654 HydrophobicContact CD1-CD1 3.93Å; D651-I654 HydrophobicContact CB-CB 4.36Å; D651-I654 HydrophobicContact CB-CD1 3.97Å; D651-I654 HydrophobicContact CB-CG1 4.29Å; D651-I654 PolarHBondContact O-N 3.22Å; D651-I654 PolarHBondContact OD1-N 3.44Å; D651-I654 VanDerWaalsContact OD1-N 3.07Å; I654-F656 VanDerWaalsContact C-N 3.34Å; I654-F656 PolarHBondContact O-N 3.34Å; I654-S657 PolarHBondContact O-N 3.26Å; I654-L658 VanDerWaalsContact O-CB 3.28Å; I654-L658 WeakPolarHBondContact O-CB 3.32Å; I654-L658 PolarHBondContact O-N 3.32Å
655M96.4Very high95.5Very high2 Ų241.9 Ų41.91%0.0121%0.214CC..Hα-helixtrans-57-47.3173.3-71178.2-167.900111.9L645 P649 D651 L658 A659 F674 H677 A678 I681L645-M655 HydrophobicContact CD1-CG 3.98Å; L645-M655 HydrophobicContact CD2-CE 4.49Å; L645-M655 HydrophobicContact CD2-CG 3.82Å; P649-M655 WeakPolarHBondContact O-CE 3.43Å; D651-M655 VanDerWaalsContact O-CG 3.29Å; D651-M655 WeakPolarHBondContact O-CG 3.39Å; D651-M655 PolarHBondContact O-N 3.04Å; D651-M655 VanDerWaalsContact O-N 3.11Å; M655-L658 PolarHBondContact O-N 2.69Å; M655-A659 VanDerWaalsContact O-CB 3.22Å; M655-A659 WeakPolarHBondContact O-CB 3.17Å; M655-A659 PolarHBondContact O-N 3.39Å; M655-F674 HydrophobicContact CB-CD1 4.32Å; M655-F674 HydrophobicContact CG-CD1 4.03Å; M655-H677 HydrophobicContact SD-CB 3.95Å; M655-A678 HydrophobicContact CB-CB 4.17Å; M655-I681 HydrophobicContact CE-CD1 4.35Å; M655-I681 HydrophobicContact SD-CD1 4.43Å
656F95.9Very high95.4Very high45 Ų4547.3 Ų47.320%0.19724%0.239CC..Hα-helixtrans-60-48.7177.9170.6-94.7000111.5H652 T653 I654 A659 N660 F675 C688 N691H652-F656 WeakPolarHBondContact O-CB 3.34Å; H652-F656 PolarHBondContact O-N 3.18Å; T653-F656 PolarHBondContact O-N 2.86Å; I654-F656 VanDerWaalsContact C-N 3.34Å; I654-F656 PolarHBondContact O-N 3.34Å; F656-A659 PolarHBondContact O-N 2.66Å; F656-N660 WeakPolarHBondContact CE1-ND2 3.46Å; F656-N660 PolarHBondContact O-N 2.95Å; F656-N660 VanDerWaalsContact O-N 3.14Å; F656-N660 PolarHBondContact O-ND2 3.26Å; F656-F675 HydrophobicContact CD2-CD1 4.12Å; F656-F675 AromaticContact CD2-CE1 3.69Å; F656-F675 HydrophobicContact CD2-CE1 3.69Å; F656-F675 AromaticContact CE2-CE1 3.96Å; F656-F675 HydrophobicContact CE2-CE1 3.96Å; F656-C688 HydrophobicContact CD2-CB 4.1Å; F656-C688 HydrophobicContact CE2-CB 4.31Å; F656-N691 HydrophobicContact CE2-CB 3.92Å; F656-N691 HydrophobicContact CZ-CB 4.32Å; F656-N691 WeakPolarHBondContact CZ-ND2 3.4Å
657S97.1Very high95.4Very high8 Ų842.9 Ų42.96%0.05622%0.22CC..Hα-helixtrans-63.7-43.7179.1-62.40000112.4N622 T653 I654 A659 N660 V661N622-S657 WeakPolarHBondContact OD1-CB 3.44Å; N622-S657 PolarHBondContact OD1-OG 2.68Å; T653-S657 PolarHBondContact O-N 3.02Å; T653-S657 PolarHBondContact O-OG 2.65Å; I654-S657 PolarHBondContact O-N 3.26Å; S657-A659 PolarHBondContact O-N 3.14Å; S657-N660 WeakPolarHBondContact O-CB 3.42Å; S657-N660 PolarHBondContact O-N 3.3Å; S657-V661 WeakPolarHBondContact O-CG2 3.3Å; S657-V661 PolarHBondContact O-N 3.26Å
658L97.4Very high95.5Very high0 Ų040.4 Ų40.40%020%0.204CC..Hα-helixtrans-65-38.5175.7179.360.5000112E638 R642 L645 I654 M655 N660 V661 L662 F674E638-L658 HydrophobicContact CB-CD1 4.4Å; E638-L658 HydrophobicContact CG-CD1 4.28Å; R642-L658 HydrophobicContact CG-CD2 4.07Å; L645-L658 HydrophobicContact CD1-CD2 3.66Å; I654-L658 VanDerWaalsContact O-CB 3.28Å; I654-L658 WeakPolarHBondContact O-CB 3.32Å; I654-L658 PolarHBondContact O-N 3.32Å; M655-L658 PolarHBondContact O-N 2.69Å; L658-N660 VanDerWaalsContact C-N 3.31Å; L658-N660 PolarHBondContact O-N 2.75Å; L658-V661 WeakPolarHBondContact O-CB 2.88Å; L658-V661 PolarHBondContact O-N 2.97Å; L658-L662 HydrophobicContact CD1-CD1 4.35Å; L658-L662 HydrophobicContact CD1-CG 4.19Å; L658-L662 HydrophobicContact CG-CD1 3.96Å; L658-L662 HydrophobicContact CG-CG 4.28Å; L658-L662 WeakPolarHBondContact O-CG 3.4Å; L658-L662 PolarHBondContact O-N 3.36Å; L658-F674 HydrophobicContact CD2-CD2 4.39Å; L658-F674 HydrophobicContact CD2-CE1 4.38Å; L658-F674 HydrophobicContact CD2-CE2 3.93Å; L658-F674 HydrophobicContact CD2-CZ 3.92Å
659A97.1Very high95.6Very high0 Ų046.5 Ų46.50%023%0.229CC..Hα-helixtrans-61.4-40.3177.100000111.6M655 F656 S657 L662 G663 S671 F674 F675M655-A659 VanDerWaalsContact O-CB 3.22Å; M655-A659 WeakPolarHBondContact O-CB 3.17Å; M655-A659 PolarHBondContact O-N 3.39Å; F656-A659 PolarHBondContact O-N 2.66Å; S657-A659 PolarHBondContact O-N 3.14Å; A659-L662 PolarHBondContact O-N 3.3Å; A659-G663 PolarHBondContact O-N 3.19Å; A659-S671 WeakPolarHBondContact O-CB 3.27Å; A659-S671 PolarHBondContact O-OG 3.1Å; A659-F674 HydrophobicContact CB-CB 3.81Å; A659-F675 HydrophobicContact CB-CD1 3.79Å; A659-F675 HydrophobicContact CB-CD2 3.62Å; A659-F675 HydrophobicContact CB-CE1 3.72Å; A659-F675 HydrophobicContact CB-CE2 3.56Å; A659-F675 HydrophobicContact CB-CG 3.73Å; A659-F675 HydrophobicContact CB-CZ 3.6Å
660N96.1Very high95.7Very high34 Ų3446.7 Ų46.718%0.18222%0.224CC..Hα-helixtrans-59.1-46.8173.5-68.7-49.6000111.6F656 S657 L658 G663 K664 F675 N691F656-N660 WeakPolarHBondContact CE1-ND2 3.46Å; F656-N660 PolarHBondContact O-N 2.95Å; F656-N660 VanDerWaalsContact O-N 3.14Å; F656-N660 PolarHBondContact O-ND2 3.26Å; S657-N660 WeakPolarHBondContact O-CB 3.42Å; S657-N660 PolarHBondContact O-N 3.3Å; L658-N660 VanDerWaalsContact C-N 3.31Å; L658-N660 PolarHBondContact O-N 2.75Å; N660-G663 PolarHBondContact O-N 3.42Å; N660-K664 PolarHBondContact O-N 2.88Å; N660-K664 VanDerWaalsContact O-N 3.08Å; N660-F675 WeakPolarHBondContact OD1-CZ 3.33Å; N660-N691 PolarHBondContact ND2-ND2 3.23Å; N660-N691 WeakPolarHBondContact OD1-CB 3.26Å; N660-N691 PolarHBondContact OD1-ND2 3.16Å
661V97.3Very high96Very high0 Ų041 Ų410%019%0.193CC..Hα-helixtrans-59.8-48.8177.2173.30000111.2V625 D629 L634 A637 E638 S657 L658 G663 K664 L665V625-V661 HydrophobicContact CG1-CG2 4.06Å; D629-V661 HydrophobicContact CB-CG2 3.82Å; L634-V661 HydrophobicContact CB-CG1 4.36Å; L634-V661 HydrophobicContact CD2-CG1 4.43Å; L634-V661 WeakPolarHBondContact O-CG1 3.46Å; A637-V661 HydrophobicContact CB-CB 4.5Å; A637-V661 HydrophobicContact CB-CG1 3.85Å; A637-V661 HydrophobicContact CB-CG2 3.81Å; E638-V661 HydrophobicContact CB-CG1 4.27Å; S657-V661 WeakPolarHBondContact O-CG2 3.3Å; S657-V661 PolarHBondContact O-N 3.26Å; L658-V661 WeakPolarHBondContact O-CB 2.88Å; L658-V661 PolarHBondContact O-N 2.97Å; V661-G663 VanDerWaalsContact C-N 3.29Å; V661-G663 PolarHBondContact O-N 3.29Å; V661-K664 WeakPolarHBondContact O-CB 3.3Å; V661-K664 PolarHBondContact O-N 2.94Å; V661-K664 VanDerWaalsContact O-N 3.1Å; V661-L665 HydrophobicContact CG1-CD1 4.06Å; V661-L665 PolarHBondContact O-N 3.27Å
662L97.3Very high96.2Very high0 Ų041.2 Ų41.20%019%0.193CC..Hα-helixtrans-62-36.8179-70.1171.1000112.3E638 L658 A659 K664 L665 Q666 K667 E670 F674E638-L662 HydrophobicContact CG-CD2 3.94Å; L658-L662 HydrophobicContact CD1-CD1 4.35Å; L658-L662 HydrophobicContact CD1-CG 4.19Å; L658-L662 HydrophobicContact CG-CD1 3.96Å; L658-L662 HydrophobicContact CG-CG 4.28Å; L658-L662 WeakPolarHBondContact O-CG 3.4Å; L658-L662 PolarHBondContact O-N 3.36Å; A659-L662 PolarHBondContact O-N 3.3Å; L662-K664 VanDerWaalsContact C-N 3.35Å; L662-L665 CarbonylContact O-C 3.4Å; L662-L665 PolarHBondContact O-N 3.4Å; L662-Q666 PolarHBondContact O-N 2.89Å; L662-Q666 VanDerWaalsContact O-N 3.16Å; L662-K667 HydrophobicContact CB-CB 4.29Å; L662-K667 HydrophobicContact CD2-CB 4.13Å; L662-K667 HydrophobicContact CD2-CD 3.68Å; L662-K667 PolarHBondContact O-N 3.49Å; L662-E670 HydrophobicContact CD1-CB 4.12Å; L662-F674 HydrophobicContact CD1-CD2 3.48Å; L662-F674 VanDerWaalsContact CD1-CD2 3.48Å; L662-F674 HydrophobicContact CD1-CE2 3.64Å
663G95.8Very high96.3Very high4 Ų442 Ų424%0.04121%0.205CC..Hα-helixtrans-64.4-38174.300000112.6A659 N660 V661 Q666 L695A659-G663 PolarHBondContact O-N 3.19Å; N660-G663 PolarHBondContact O-N 3.42Å; V661-G663 VanDerWaalsContact C-N 3.29Å; V661-G663 PolarHBondContact O-N 3.29Å; G663-Q666 PolarHBondContact O-N 2.96Å; G663-L695 VanDerWaalsContact CA-CD1 3.48Å
664K94.9Very high96.5Very high83 Ų8341.8 Ų41.836%0.36120%0.201SC..Hα-helixtrans-67.4-35.5172.8-71.1170172.1175.10112.4D629 L634 N660 V661 L662 Q666D629-K664 WeakPolarHBondContact OD1-CD 3.48Å; D629-K664 WeakPolarHBondContact OD1-CE 3.49Å; D629-K664 IonicContact OD1-NZ 3.29Å; D629-K664 PolarHBondContact OD1-NZ 3.4Å; D629-K664 IonicContact OD2-NZ 2.82Å; D629-K664 PolarHBondContact OD2-NZ 2.94Å; L634-K664 HydrophobicContact CD1-CB 3.79Å; L634-K664 HydrophobicContact CD2-CB 4.36Å; L634-K664 HydrophobicContact CD2-CD 4.04Å; N660-K664 PolarHBondContact O-N 2.88Å; N660-K664 VanDerWaalsContact O-N 3.08Å; V661-K664 WeakPolarHBondContact O-CB 3.3Å; V661-K664 PolarHBondContact O-N 2.94Å; V661-K664 VanDerWaalsContact O-N 3.1Å; L662-K664 VanDerWaalsContact C-N 3.35Å; K664-Q666 PolarHBondContact O-N 2.97Å
665L95.7Very high96.5Very high59 Ų5941.9 Ų41.931%0.30920%0.201SC..THydrogen-bonded Turntrans-76.23.5172.6-69171.7000114.3L634 E638 V661 L662 K667L634-L665 HydrophobicContact CB-CD1 4.28Å; L634-L665 HydrophobicContact CB-CD2 3.68Å; L634-L665 HydrophobicContact CB-CG 3.94Å; L634-L665 HydrophobicContact CD1-CD2 4.04Å; L634-L665 HydrophobicContact CD1-CG 4.28Å; E638-L665 HydrophobicContact CB-CD1 4.12Å; E638-L665 VanDerWaalsContact OE2-CD1 3.26Å; E638-L665 WeakPolarHBondContact OE2-CD1 3.25Å; V661-L665 HydrophobicContact CG1-CD1 4.06Å; V661-L665 PolarHBondContact O-N 3.27Å; L662-L665 CarbonylContact O-C 3.4Å; L662-L665 PolarHBondContact O-N 3.4Å; L665-K667 HydrophobicContact CB-CG 4.42Å; L665-K667 PolarHBondContact O-N 3.47Å
666Q95Very high96.5Very high132 Ų13245 Ų4562%0.61722%0.217SC*.THydrogen-bonded Turntrans62.217.3-177.9-48.5-177.620.600114.8L662 G663 K664 Y668L662-Q666 PolarHBondContact O-N 2.89Å; L662-Q666 VanDerWaalsContact O-N 3.16Å; G663-Q666 PolarHBondContact O-N 2.96Å; K664-Q666 PolarHBondContact O-N 2.97Å; Q666-Y668 HydrophobicContact CB-CE1 4.45Å; Q666-Y668 HydrophobicContact CB-CE2 3.86Å; Q666-Y668 VanDerWaalsContact O-CD2 3.29Å; Q666-Y668 WeakPolarHBondContact O-CD2 3.22Å; Q666-Y668 PolarHBondContact O-N 3.08Å
667K96.9Very high96.4Very high78 Ų7846 Ų4634%0.33922%0.223SC..  trans-81.760.5172.3-67.3178.4175173.80110.3E638 L662 L665 K669 E670 S671E638-K667 IonicContact OE1-NZ 3.79Å; E638-K667 PolarHBondContact OE1-NZ 2.89Å; E638-K667 IonicContact OE2-NZ 2.67Å; E638-K667 PolarHBondContact OE2-NZ 3.26Å; L662-K667 HydrophobicContact CB-CB 4.29Å; L662-K667 HydrophobicContact CD2-CB 4.13Å; L662-K667 HydrophobicContact CD2-CD 3.68Å; L662-K667 PolarHBondContact O-N 3.49Å; L665-K667 HydrophobicContact CB-CG 4.42Å; L665-K667 PolarHBondContact O-N 3.47Å; K667-K669 PolarHBondContact O-N 3.25Å; K667-E670 PolarHBondContact O-N 3.39Å; K667-S671 PolarHBondContact O-N 2.97Å
668Y96.6Very high96.3Very high43 Ų4345.8 Ų45.817%0.16922%0.222CC..Hα-helixtrans-61.5-41.2-164.1-58.8-62.7000114.6Q666 E670 S671 E672 L695 R698 W699Q666-Y668 HydrophobicContact CB-CE1 4.45Å; Q666-Y668 HydrophobicContact CB-CE2 3.86Å; Q666-Y668 VanDerWaalsContact O-CD2 3.29Å; Q666-Y668 WeakPolarHBondContact O-CD2 3.22Å; Q666-Y668 PolarHBondContact O-N 3.08Å; Y668-E670 PolarHBondContact O-N 3.34Å; Y668-S671 PolarHBondContact O-N 3.14Å; Y668-E672 WeakPolarHBondContact O-CB 3.41Å; Y668-E672 PolarHBondContact O-N 3.44Å; Y668-L695 HydrophobicContact CD1-CD1 3.72Å; Y668-L695 HydrophobicContact CD1-CG 4.49Å; Y668-L695 HydrophobicContact CE1-CD1 4.42Å; Y668-R698 HydrophobicContact CE1-CB 4.42Å; Y668-W699 VanDerWaalsContact CB-CE3 3.49Å; Y668-W699 HydrophobicContact CD1-CB 3.96Å; Y668-W699 HydrophobicContact CD1-CD2 4.5Å; Y668-W699 HydrophobicContact CD1-CG 4.13Å; Y668-W699 HydrophobicContact CD2-CB 4.33Å; Y668-W699 AromaticContact CD2-CD1 3.53Å; Y668-W699 HydrophobicContact CD2-CD2 4.24Å; Y668-W699 AromaticContact CD2-CG 3.82Å; Y668-W699 HydrophobicContact CD2-CG 3.82Å; Y668-W699 AromaticContact CD2-NE1 3.86Å; Y668-W699 HydrophobicContact CE1-CB 4.27Å; Y668-W699 HydrophobicContact CE2-CG 4.43Å; Y668-W699 HydrophobicContact CG-CB 4Å; Y668-W699 AromaticContact CG-CD1 3.85Å; Y668-W699 AromaticContact CG-CD2 3.82Å; Y668-W699 HydrophobicContact CG-CD2 3.82Å; Y668-W699 HydrophobicContact CG-CE3 4.3Å; Y668-W699 AromaticContact CG-CG 3.65Å; Y668-W699 HydrophobicContact CG-CG 3.65Å
669K96.3Very high96.1Very high159 Ų15946.5 Ų46.569%0.69123%0.225SC*.Hα-helixtrans-63.4-41.2179.1-70.8-178.3177.9-178.70112.5K667 S673 W699K667-K669 PolarHBondContact O-N 3.25Å; K669-S673 PolarHBondContact O-N 3.44Å; K669-S673 VanDerWaalsContact O-N 3.08Å; K669-W699 HydrophobicContact CB-CH2 4.35Å; K669-W699 HydrophobicContact CG-CH2 3.63Å; K669-W699 HydrophobicContact CG-CZ2 3.81Å
670E95.9Very high96Very high79 Ų7956.1 Ų56.137%0.36926%0.261SS..Hα-helixtrans-70.7-42.6178.5-65-175.1-109.300111R642 L662 K667 Y668 E672 S673 F674R642-E670 IonicContact CZ-OE2 2.76Å; R642-E670 IonicContact NH1-OE2 2.81Å; R642-E670 PolarHBondContact NH1-OE2 2.87Å; R642-E670 IonicContact NH2-OE1 3.24Å; R642-E670 IonicContact NH2-OE2 2.66Å; R642-E670 PolarHBondContact NH2-OE2 3.44Å; L662-E670 HydrophobicContact CD1-CB 4.12Å; K667-E670 PolarHBondContact O-N 3.39Å; Y668-E670 PolarHBondContact O-N 3.34Å; E670-E672 PolarHBondContact O-N 3.34Å; E670-S673 WeakPolarHBondContact O-CB 3.35Å; E670-S673 PolarHBondContact O-N 3.48Å; E670-F674 VanDerWaalsContact O-CD2 3.25Å; E670-F674 WeakPolarHBondContact O-CD2 3.36Å; E670-F674 PolarHBondContact O-N 2.9Å; E670-F674 VanDerWaalsContact O-N 3.08Å
671S97.2Very high95.7Very high0 Ų058 Ų580%027%0.271CS..Hα-helixtrans-57.2-47.7173.7-179.30000111.9A659 K667 Y668 S673 F674 F675 L695A659-S671 WeakPolarHBondContact O-CB 3.27Å; A659-S671 PolarHBondContact O-OG 3.1Å; K667-S671 PolarHBondContact O-N 2.97Å; Y668-S671 PolarHBondContact O-N 3.14Å; S671-S673 VanDerWaalsContact C-N 3.34Å; S671-S673 PolarHBondContact O-N 3.42Å; S671-F674 PolarHBondContact O-N 3.32Å; S671-F675 VanDerWaalsContact O-CD2 3.27Å; S671-F675 WeakPolarHBondContact O-CD2 3.33Å; S671-F675 PolarHBondContact O-N 3.49Å; S671-F675 WeakPolarHBondContact OG-CE2 3.48Å; S671-L695 VanDerWaalsContact OG-CD1 3.28Å; S671-L695 WeakPolarHBondContact OG-CD1 3.19Å; S671-L695 WeakPolarHBondContact OG-CD2 3.33Å
672E97.3Very high95.5Very high35 Ų3563.2 Ų63.216%0.16429%0.294CS..Hα-helixtrans-56.7-46.4175.1176.4-180-140.100111.2Y668 E670 F674 F675 L676 L695 Y696 W699 K701Y668-E672 WeakPolarHBondContact O-CB 3.41Å; Y668-E672 PolarHBondContact O-N 3.44Å; E670-E672 PolarHBondContact O-N 3.34Å; E672-F674 PolarHBondContact O-N 3.47Å; E672-F675 PolarHBondContact O-N 3.08Å; E672-L676 HydrophobicContact CG-CD1 3.9Å; E672-L676 HydrophobicContact CG-CG 4.38Å; E672-L676 WeakPolarHBondContact O-CB 3.47Å; E672-L676 VanDerWaalsContact O-CG 3.26Å; E672-L676 WeakPolarHBondContact O-CG 3.28Å; E672-L676 PolarHBondContact O-N 3.36Å; E672-L695 HydrophobicContact CB-CD2 4.08Å; E672-Y696 HydrophobicContact CG-CE1 4.07Å; E672-Y696 WeakPolarHBondContact OE1-CE1 3.29Å; E672-Y696 PolarHBondContact OE1-OH 3.44Å; E672-W699 HydrophobicContact CB-CZ3 4.07Å; E672-W699 HydrophobicContact CG-CZ3 4.46Å; E672-W699 VanDerWaalsContact OE2-CH2 3.23Å; E672-W699 WeakPolarHBondContact OE2-CH2 3.44Å; E672-W699 WeakPolarHBondContact OE2-CZ3 3.33Å; E672-K701 IonicContact OE1-NZ 2.97Å; E672-K701 PolarHBondContact OE1-NZ 2.74Å; E672-K701 IonicContact OE2-NZ 3.88Å; E672-K701 PolarHBondContact OE2-NZ 3.37Å
673S96.4Very high95.2Very high77 Ų7766.9 Ų66.954%0.53832%0.317SS..Hα-helixtrans-56.7-47.5177.5-174.30000112.3K669 E670 S671 L676 H677K669-S673 PolarHBondContact O-N 3.44Å; K669-S673 VanDerWaalsContact O-N 3.08Å; E670-S673 WeakPolarHBondContact O-CB 3.35Å; E670-S673 PolarHBondContact O-N 3.48Å; S671-S673 VanDerWaalsContact C-N 3.34Å; S671-S673 PolarHBondContact O-N 3.42Å; S673-L676 PolarHBondContact O-N 2.92Å; S673-H677 WeakPolarHBondContact O-CB 3.43Å; S673-H677 PolarHBondContact O-N 3.25Å
674F96.9Very high95Very high40 Ų4072.8 Ų72.818%0.17535%0.348CS..Hα-helixtrans-67.3-41.1179.3-78-63.8000113L645 M655 L658 A659 L662 E670 S671 E672 H677 A678L645-F674 HydrophobicContact CD1-CD1 3.99Å; L645-F674 HydrophobicContact CD1-CE1 3.46Å; L645-F674 VanDerWaalsContact CD1-CE1 3.46Å; L645-F674 HydrophobicContact CD1-CZ 4.1Å; M655-F674 HydrophobicContact CB-CD1 4.32Å; M655-F674 HydrophobicContact CG-CD1 4.03Å; L658-F674 HydrophobicContact CD2-CD2 4.39Å; L658-F674 HydrophobicContact CD2-CE1 4.38Å; L658-F674 HydrophobicContact CD2-CE2 3.93Å; L658-F674 HydrophobicContact CD2-CZ 3.92Å; A659-F674 HydrophobicContact CB-CB 3.81Å; L662-F674 HydrophobicContact CD1-CD2 3.48Å; L662-F674 VanDerWaalsContact CD1-CD2 3.48Å; L662-F674 HydrophobicContact CD1-CE2 3.64Å; E670-F674 VanDerWaalsContact O-CD2 3.25Å; E670-F674 WeakPolarHBondContact O-CD2 3.36Å; E670-F674 PolarHBondContact O-N 2.9Å; E670-F674 VanDerWaalsContact O-N 3.08Å; S671-F674 PolarHBondContact O-N 3.32Å; E672-F674 PolarHBondContact O-N 3.47Å; F674-H677 PolarHBondContact O-N 3.44Å; F674-A678 WeakPolarHBondContact O-CB 3.35Å; F674-A678 PolarHBondContact O-N 3.49Å
675F97.1Very high94.8Very high1 Ų169.5 Ų69.50%0.00434%0.337CS..Hα-helixtrans-62-45.3174.1-79.6-57.1000112.1F656 A659 N660 S671 E672 H677 A678 L679 N691 L692 L695F656-F675 HydrophobicContact CD2-CD1 4.12Å; F656-F675 AromaticContact CD2-CE1 3.69Å; F656-F675 HydrophobicContact CD2-CE1 3.69Å; F656-F675 AromaticContact CE2-CE1 3.96Å; F656-F675 HydrophobicContact CE2-CE1 3.96Å; A659-F675 HydrophobicContact CB-CD1 3.79Å; A659-F675 HydrophobicContact CB-CD2 3.62Å; A659-F675 HydrophobicContact CB-CE1 3.72Å; A659-F675 HydrophobicContact CB-CE2 3.56Å; A659-F675 HydrophobicContact CB-CG 3.73Å; A659-F675 HydrophobicContact CB-CZ 3.6Å; N660-F675 WeakPolarHBondContact OD1-CZ 3.33Å; S671-F675 VanDerWaalsContact O-CD2 3.27Å; S671-F675 WeakPolarHBondContact O-CD2 3.33Å; S671-F675 PolarHBondContact O-N 3.49Å; S671-F675 WeakPolarHBondContact OG-CE2 3.48Å; E672-F675 PolarHBondContact O-N 3.08Å; F675-H677 VanDerWaalsContact C-N 3.3Å; F675-H677 PolarHBondContact O-N 3.06Å; F675-A678 PolarHBondContact O-N 2.97Å; F675-L679 WeakPolarHBondContact O-CB 3.33Å; F675-L679 WeakPolarHBondContact O-CG 3.5Å; F675-L679 PolarHBondContact O-N 3.42Å; F675-N691 HydrophobicContact CE1-CB 3.91Å; F675-N691 HydrophobicContact CZ-CB 3.89Å; F675-L692 HydrophobicContact CB-CB 4.23Å; F675-L692 HydrophobicContact CB-CD1 3.82Å; F675-L692 HydrophobicContact CB-CD2 4.24Å; F675-L692 HydrophobicContact CB-CG 4.31Å; F675-L692 HydrophobicContact CD2-CB 4.31Å; F675-L692 HydrophobicContact CD2-CD1 3.83Å; F675-L692 HydrophobicContact CG-CB 4.14Å; F675-L692 HydrophobicContact CG-CD1 4.1Å; F675-L695 HydrophobicContact CD2-CD2 3.89Å; F675-L695 HydrophobicContact CE2-CB 4.19Å; F675-L695 HydrophobicContact CE2-CD2 4.06Å
676L95.6Very high94.7Very high67 Ų6767.3 Ų67.335%0.35133%0.327SS..Hα-helixtrans-63.9-37.5178.1-69.4177.4000111.4E672 S673 L679 R680 L692E672-L676 HydrophobicContact CG-CD1 3.9Å; E672-L676 HydrophobicContact CG-CG 4.38Å; E672-L676 WeakPolarHBondContact O-CB 3.47Å; E672-L676 VanDerWaalsContact O-CG 3.26Å; E672-L676 WeakPolarHBondContact O-CG 3.28Å; E672-L676 PolarHBondContact O-N 3.36Å; S673-L676 PolarHBondContact O-N 2.92Å; L676-L679 PolarHBondContact O-N 2.91Å; L676-R680 WeakPolarHBondContact O-CG 3.46Å; L676-R680 PolarHBondContact O-N 3.42Å; L676-L692 HydrophobicContact CD2-CD2 4.04Å
677H94.4Very high94.5Very high67 Ų6764.5 Ų64.531%0.3132%0.322SS..Hα-helixtrans-65.8-46.6174.3-162.4171.6000111.5M655 S673 F674 F675 L679 R680 I681M655-H677 HydrophobicContact SD-CB 3.95Å; S673-H677 WeakPolarHBondContact O-CB 3.43Å; S673-H677 PolarHBondContact O-N 3.25Å; F674-H677 PolarHBondContact O-N 3.44Å; F675-H677 VanDerWaalsContact C-N 3.3Å; F675-H677 PolarHBondContact O-N 3.06Å; H677-L679 PolarHBondContact O-N 2.96Å; H677-R680 WeakPolarHBondContact O-CB 3.49Å; H677-R680 PolarHBondContact O-N 3.01Å; H677-I681 PolarHBondContact O-N 3.46Å
678A94.3Very high94.4Very high4 Ų461 Ų613%0.03331%0.307CS..Hα-helixtrans-57.1-39174.700000111.9H652 M655 F674 F675 I681 K682H652-A678 HydrophobicContact CB-CB 4.21Å; M655-A678 HydrophobicContact CB-CB 4.17Å; F674-A678 WeakPolarHBondContact O-CB 3.35Å; F674-A678 PolarHBondContact O-N 3.49Å; F675-A678 PolarHBondContact O-N 2.97Å; A678-I681 PolarHBondContact O-N 2.96Å; A678-K682 PolarHBondContact O-N 3.19Å
679L94.5Very high94.4Very high15 Ų1559.7 Ų59.78%0.07930%0.302CS..Hα-helixtrans-71.6-28.3175.7-73.6169.2000114F675 L676 H677 I681 K682 P683 C688 L692F675-L679 WeakPolarHBondContact O-CB 3.33Å; F675-L679 WeakPolarHBondContact O-CG 3.5Å; F675-L679 PolarHBondContact O-N 3.42Å; L676-L679 PolarHBondContact O-N 2.91Å; H677-L679 PolarHBondContact O-N 2.96Å; L679-I681 PolarHBondContact O-N 3.2Å; L679-K682 CarbonylContact O-C 3.57Å; L679-K682 VanDerWaalsContact O-C 3.27Å; L679-P683 WeakPolarHBondContact O-CA 3.47Å; L679-P683 WeakPolarHBondContact O-CD 3.43Å; L679-P683 WeakPolarHBondContact O-CG 3.4Å; L679-C688 HydrophobicContact CD2-CB 3.76Å; L679-C688 HydrophobicContact CG-CB 4.26Å; L679-L692 HydrophobicContact CD1-CD2 3.78Å
680R94.4Very high94.3Very high201 Ų20152.1 Ų52.176%0.75827%0.269SS*.Hα-helixtrans-63.4-36170.8-74.7174.6-173.5174.41.8111.3L676 H677L676-R680 WeakPolarHBondContact O-CG 3.46Å; L676-R680 PolarHBondContact O-N 3.42Å; H677-R680 WeakPolarHBondContact O-CB 3.49Å; H677-R680 PolarHBondContact O-N 3.01Å
681I90.7Very high94.3Very high74 Ų7450.8 Ų50.838%0.37927%0.265SS..Hα-helixtrans-78-45.3178.2-58.3171.9000110.4N650 H652 M655 H677 A678 L679N650-I681 WeakPolarHBondContact O-CD1 3.28Å; H652-I681 HydrophobicContact CB-CB 4.27Å; H652-I681 HydrophobicContact CB-CD1 4.19Å; H652-I681 HydrophobicContact CB-CG2 4.3Å; M655-I681 HydrophobicContact CE-CD1 4.35Å; M655-I681 HydrophobicContact SD-CD1 4.43Å; H677-I681 PolarHBondContact O-N 3.46Å; A678-I681 PolarHBondContact O-N 2.96Å; L679-I681 PolarHBondContact O-N 3.2Å
682K91.6Very high94.3Very high110 Ų11050.8 Ų50.848%0.47827%0.265SS..  trans-12885179.7-163.7174.9-178.3176.30111.4A678 L679 N684 A685A678-K682 PolarHBondContact O-N 3.19Å; L679-K682 CarbonylContact O-C 3.57Å; L679-K682 VanDerWaalsContact O-C 3.27Å; K682-N684 VanDerWaalsContact C-N 3.31Å; K682-N684 PolarHBondContact O-N 3.08Å; K682-A685 HydrophobicContact CB-CB 4.45Å; K682-A685 HydrophobicContact CD-CB 4.24Å; K682-A685 HydrophobicContact CG-CB 4.14Å; K682-A685 WeakPolarHBondContact O-CB 3.36Å; K682-A685 PolarHBondContact O-N 2.94Å
683P90.8Very high94.2Very high76 Ų7649.1 Ų49.149%0.49426%0.257SS..THydrogen-bonded Turntrans-64.7-31-173.9-24.133.7000114.4L679 A685 H689L679-P683 WeakPolarHBondContact O-CA 3.47Å; L679-P683 WeakPolarHBondContact O-CD 3.43Å; L679-P683 WeakPolarHBondContact O-CG 3.4Å; P683-A685 VanDerWaalsContact C-N 3.31Å; P683-A685 PolarHBondContact O-N 3.42Å; P683-H689 PolarHBondContact O-NE2 3Å
684N91.4Very high94.2Very high128 Ų12847.4 Ų47.468%0.68424%0.243SC*.THydrogen-bonded Turntrans-94.525.3-174.7-62.3-17.4000112.8K682 A686 L715K682-N684 VanDerWaalsContact C-N 3.31Å; K682-N684 PolarHBondContact O-N 3.08Å; N684-A686 PolarHBondContact O-N 3.28Å; N684-L715 HydrophobicContact CB-CD2 4.18Å
685A91.9Very high94.2Very high15 Ų1545.8 Ų45.812%0.12424%0.236CC..  trans-83.794.8178.200000110.8K682 P683 S687 C688 H689K682-A685 HydrophobicContact CB-CB 4.45Å; K682-A685 HydrophobicContact CD-CB 4.24Å; K682-A685 HydrophobicContact CG-CB 4.14Å; K682-A685 WeakPolarHBondContact O-CB 3.36Å; K682-A685 PolarHBondContact O-N 2.94Å; P683-A685 VanDerWaalsContact C-N 3.31Å; P683-A685 PolarHBondContact O-N 3.42Å; A685-S687 VanDerWaalsContact C-N 3.34Å; A685-S687 PolarHBondContact O-N 3.49Å; A685-C688 HydrophobicContact CB-CB 3.71Å; A685-C688 WeakPolarHBondContact O-CB 3.42Å; A685-C688 PolarHBondContact O-N 3.45Å; A685-H689 PolarHBondContact O-N 3.41Å; A685-H689 VanDerWaalsContact O-N 3.13Å
686A92.8Very high94.2Very high13 Ų1346 Ų4611%0.10724%0.237CC..Hα-helixtrans-52.3-49.2179.700000112.3N684 C688 H689 G690 S712 L715 D716N684-A686 PolarHBondContact O-N 3.28Å; A686-C688 VanDerWaalsContact C-N 3.26Å; A686-C688 PolarHBondContact O-N 3.34Å; A686-H689 PolarHBondContact O-N 3.2Å; A686-H689 VanDerWaalsContact O-N 3.08Å; A686-G690 PolarHBondContact O-N 2.94Å; A686-S712 PolarHBondContact O-OG 2.96Å; A686-L715 HydrophobicContact CB-CB 3.8Å; A686-D716 HydrophobicContact CB-CB 3.58Å
687S92.2Very high94.1Very high73 Ų7344.2 Ų44.251%0.5123%0.227SC..Hα-helixtrans-57-35.7177.256.90000113.9A685 G690 N691A685-S687 VanDerWaalsContact C-N 3.34Å; A685-S687 PolarHBondContact O-N 3.49Å; S687-G690 PolarHBondContact O-N 3.17Å; S687-N691 PolarHBondContact O-N 3.45Å
688C94.1Very high94Very high5 Ų546.9 Ų46.93%0.03424%0.235CC..Hα-helixtrans-68.3-43.8176.3-163.10000111.5F656 L679 A685 A686 L692F656-C688 HydrophobicContact CD2-CB 4.1Å; F656-C688 HydrophobicContact CE2-CB 4.31Å; L679-C688 HydrophobicContact CD2-CB 3.76Å; L679-C688 HydrophobicContact CG-CB 4.26Å; A685-C688 HydrophobicContact CB-CB 3.71Å; A685-C688 WeakPolarHBondContact O-CB 3.42Å; A685-C688 PolarHBondContact O-N 3.45Å; A686-C688 VanDerWaalsContact C-N 3.26Å; A686-C688 PolarHBondContact O-N 3.34Å; C688-L692 VanDerWaalsContact O-CB 3.27Å; C688-L692 WeakPolarHBondContact O-CB 3.4Å; C688-L692 PolarHBondContact O-N 3.2Å
689H95.8Very high94.1Very high14 Ų1450 Ų507%0.06525%0.246CC..Hα-helixtrans-64-42.2172.9-75.2-53.6000112.7P683 A685 A686 L692 A693 H708 L711P683-H689 PolarHBondContact O-NE2 3Å; A685-H689 PolarHBondContact O-N 3.41Å; A685-H689 VanDerWaalsContact O-N 3.13Å; A686-H689 PolarHBondContact O-N 3.2Å; A686-H689 VanDerWaalsContact O-N 3.08Å; H689-L692 PolarHBondContact O-N 3.28Å; H689-A693 WeakPolarHBondContact O-CB 3.41Å; H689-A693 PolarHBondContact O-N 3.48Å; H689-H708 AromaticContact CE1-ND1 3.85Å; H689-H708 AromaticContact ND1-CE1 3.64Å; H689-H708 AromaticContact ND1-ND1 3.08Å; H689-H708 PolarHBondContact ND1-ND1 2.92Å; H689-L711 WeakPolarHBondContact CE1-CD2 3.45Å; H689-L711 WeakPolarHBondContact NE2-CD2 3.26Å
690G95.1Very high94Very high0 Ų051.6 Ų51.60%027%0.265CS..Hα-helixtrans-59-47.5176.400000112.3A686 S687 A693 V694 S712A686-G690 PolarHBondContact O-N 2.94Å; S687-G690 PolarHBondContact O-N 3.17Å; G690-A693 WeakPolarHBondContact O-CB 3.45Å; G690-A693 PolarHBondContact O-N 2.98Å; G690-V694 WeakPolarHBondContact O-CG2 3.35Å; G690-V694 PolarHBondContact O-N 2.92Å; G690-S712 PolarHBondContact N-OG 3.42Å
691N95.5Very high94Very high51 Ų5145.1 Ų45.127%0.27324%0.242SC..Hα-helixtrans-73.8-33179.9-74.911.5000113.3F656 N660 F675 S687 A693 V694 L695F656-N691 HydrophobicContact CE2-CB 3.92Å; F656-N691 HydrophobicContact CZ-CB 4.32Å; F656-N691 WeakPolarHBondContact CZ-ND2 3.4Å; N660-N691 PolarHBondContact ND2-ND2 3.23Å; N660-N691 WeakPolarHBondContact OD1-CB 3.26Å; N660-N691 PolarHBondContact OD1-ND2 3.16Å; F675-N691 HydrophobicContact CE1-CB 3.91Å; F675-N691 HydrophobicContact CZ-CB 3.89Å; S687-N691 PolarHBondContact O-N 3.45Å; N691-A693 VanDerWaalsContact C-N 3.29Å; N691-A693 PolarHBondContact O-N 2.87Å; N691-V694 WeakPolarHBondContact O-CB 3.38Å; N691-V694 PolarHBondContact O-N 3.21Å; N691-L695 PolarHBondContact O-N 3.26Å
692L96.4Very high94.1Very high0 Ų042.7 Ų42.70%023%0.23CC..Hα-helixtrans-63.6-36.8170179.656.6000111.3F675 L676 L679 C688 H689 L695 Y696F675-L692 HydrophobicContact CB-CB 4.23Å; F675-L692 HydrophobicContact CB-CD1 3.82Å; F675-L692 HydrophobicContact CB-CD2 4.24Å; F675-L692 HydrophobicContact CB-CG 4.31Å; F675-L692 HydrophobicContact CD2-CB 4.31Å; F675-L692 HydrophobicContact CD2-CD1 3.83Å; F675-L692 HydrophobicContact CG-CB 4.14Å; F675-L692 HydrophobicContact CG-CD1 4.1Å; L676-L692 HydrophobicContact CD2-CD2 4.04Å; L679-L692 HydrophobicContact CD1-CD2 3.78Å; C688-L692 VanDerWaalsContact O-CB 3.27Å; C688-L692 WeakPolarHBondContact O-CB 3.4Å; C688-L692 PolarHBondContact O-N 3.2Å; H689-L692 PolarHBondContact O-N 3.28Å; L692-L695 HydrophobicContact CD1-CD2 3.99Å; L692-L695 WeakPolarHBondContact O-CB 3.39Å; L692-L695 PolarHBondContact O-N 2.96Å; L692-Y696 HydrophobicContact CD1-CD2 4.26Å; L692-Y696 HydrophobicContact CD1-CE1 4.22Å; L692-Y696 HydrophobicContact CD1-CE2 3.7Å; L692-Y696 HydrophobicContact CD2-CE2 4.07Å; L692-Y696 HydrophobicContact CG-CD2 4.11Å; L692-Y696 HydrophobicContact CG-CE2 3.6Å; L692-Y696 WeakPolarHBondContact O-CD2 3.48Å; L692-Y696 PolarHBondContact O-N 2.82Å
693A96.4Very high94.2Very high0 Ų043.3 Ų43.30%024%0.235CC..Hα-helixtrans-64.2-42.5172.800000111.9H689 G690 N691 L695 Y696 H697 A705 H708 Y709H689-A693 WeakPolarHBondContact O-CB 3.41Å; H689-A693 PolarHBondContact O-N 3.48Å; G690-A693 WeakPolarHBondContact O-CB 3.45Å; G690-A693 PolarHBondContact O-N 2.98Å; N691-A693 VanDerWaalsContact C-N 3.29Å; N691-A693 PolarHBondContact O-N 2.87Å; A693-L695 VanDerWaalsContact C-N 3.31Å; A693-L695 PolarHBondContact O-N 2.96Å; A693-Y696 PolarHBondContact O-N 3.35Å; A693-H697 WeakPolarHBondContact O-CB 3.41Å; A693-H697 PolarHBondContact O-N 3.16Å; A693-A705 WeakPolarHBondContact CB-O 3.43Å; A693-A705 WeakPolarHBondContact O-CB 3.39Å; A693-H708 HydrophobicContact CB-CB 3.69Å; A693-Y709 HydrophobicContact CB-CD1 3.44Å; A693-Y709 VanDerWaalsContact CB-CD1 3.44Å; A693-Y709 HydrophobicContact CB-CD2 3.75Å; A693-Y709 HydrophobicContact CB-CE1 3.52Å; A693-Y709 HydrophobicContact CB-CE2 3.84Å; A693-Y709 HydrophobicContact CB-CG 3.54Å
694V95.8Very high94.4Very high41 Ų4143 Ų4325%0.24823%0.228CC..Hα-helixtrans-59.3-42.1172.9173.10000111.2G690 N691 H697 R698 Y709 N725G690-V694 WeakPolarHBondContact O-CG2 3.35Å; G690-V694 PolarHBondContact O-N 2.92Å; N691-V694 WeakPolarHBondContact O-CB 3.38Å; N691-V694 PolarHBondContact O-N 3.21Å; V694-H697 PolarHBondContact O-N 2.89Å; V694-R698 WeakPolarHBondContact O-CG 3.39Å; V694-R698 PolarHBondContact O-N 3Å; V694-Y709 VanDerWaalsContact CA-OH 3.31Å; V694-Y709 WeakPolarHBondContact CA-OH 3.3Å; V694-Y709 HydrophobicContact CG2-CE1 4.04Å; V694-Y709 VanDerWaalsContact CG2-OH 3.32Å; V694-Y709 WeakPolarHBondContact CG2-OH 3.06Å; V694-Y709 PolarHBondContact N-OH 2.68Å; V694-N725 HydrophobicContact CG2-CB 4.44Å
695L96.9Very high94.6Very high6 Ų636.9 Ų36.93%0.03120%0.196CC..Hα-helixtrans-57.6-51.7174.2-178.874.5000111.2G663 Y668 S671 E672 F675 N691 L692 A693 H697 R698 W699G663-L695 VanDerWaalsContact CA-CD1 3.48Å; Y668-L695 HydrophobicContact CD1-CD1 3.72Å; Y668-L695 HydrophobicContact CD1-CG 4.49Å; Y668-L695 HydrophobicContact CE1-CD1 4.42Å; S671-L695 VanDerWaalsContact OG-CD1 3.28Å; S671-L695 WeakPolarHBondContact OG-CD1 3.19Å; S671-L695 WeakPolarHBondContact OG-CD2 3.33Å; E672-L695 HydrophobicContact CB-CD2 4.08Å; F675-L695 HydrophobicContact CD2-CD2 3.89Å; F675-L695 HydrophobicContact CE2-CB 4.19Å; F675-L695 HydrophobicContact CE2-CD2 4.06Å; N691-L695 PolarHBondContact O-N 3.26Å; L692-L695 HydrophobicContact CD1-CD2 3.99Å; L692-L695 WeakPolarHBondContact O-CB 3.39Å; L692-L695 PolarHBondContact O-N 2.96Å; A693-L695 VanDerWaalsContact C-N 3.31Å; A693-L695 PolarHBondContact O-N 2.96Å; L695-H697 VanDerWaalsContact C-N 3.32Å; L695-H697 PolarHBondContact O-N 3Å; L695-R698 PolarHBondContact O-N 3.16Å; L695-W699 WeakPolarHBondContact O-CB 3.42Å; L695-W699 PolarHBondContact O-N 3.33Å
696Y97.3Very high94.8Very high7 Ų739.5 Ų39.53%0.02720%0.204CC..Hα-helixtrans-63.7-37.4179.5-71.1-37.7000113.1E672 L692 A693 W699 G700 K701 L704 H708E672-Y696 HydrophobicContact CG-CE1 4.07Å; E672-Y696 WeakPolarHBondContact OE1-CE1 3.29Å; E672-Y696 PolarHBondContact OE1-OH 3.44Å; L692-Y696 HydrophobicContact CD1-CD2 4.26Å; L692-Y696 HydrophobicContact CD1-CE1 4.22Å; L692-Y696 HydrophobicContact CD1-CE2 3.7Å; L692-Y696 HydrophobicContact CD2-CE2 4.07Å; L692-Y696 HydrophobicContact CG-CD2 4.11Å; L692-Y696 HydrophobicContact CG-CE2 3.6Å; L692-Y696 WeakPolarHBondContact O-CD2 3.48Å; L692-Y696 PolarHBondContact O-N 2.82Å; A693-Y696 PolarHBondContact O-N 3.35Å; Y696-W699 HydrophobicContact CD1-CE3 4.09Å; Y696-W699 HydrophobicContact CE1-CE3 4.3Å; Y696-W699 HydrophobicContact CE1-CZ3 4.34Å; Y696-W699 CarbonylContact O-C 3.31Å; Y696-W699 PolarHBondContact O-N 3.32Å; Y696-G700 PolarHBondContact O-N 2.84Å; Y696-K701 HydrophobicContact CD1-CB 4.04Å; Y696-K701 HydrophobicContact CD1-CD 3.61Å; Y696-K701 HydrophobicContact CD1-CG 4.45Å; Y696-K701 HydrophobicContact CE1-CD 3.87Å; Y696-K701 HydrophobicContact CG-CB 4.29Å; Y696-K701 PolarHBondContact O-N 2.94Å; Y696-L704 HydrophobicContact CD1-CB 4.49Å; Y696-L704 HydrophobicContact CD2-CB 3.69Å; Y696-L704 HydrophobicContact CE1-CD1 4.48Å; Y696-L704 HydrophobicContact CE2-CB 3.97Å; Y696-L704 HydrophobicContact CG-CB 3.98Å; Y696-H708 AromaticContact CD2-CD2 3.88Å; Y696-H708 AromaticContact CE2-CD2 3.47Å; Y696-H708 VanDerWaalsContact CE2-CD2 3.47Å; Y696-H708 WeakPolarHBondContact CE2-CD2 3.07Å; Y696-H708 AromaticContact CE2-NE2 3.86Å
697H94.4Very high94.9Very high29 Ų2945.1 Ų45.113%0.13423%0.226CC..Hα-helixtrans-62.1-45.2175.9-170.5179.5000110.5A693 V694 L695 G700 A705 Y709A693-H697 WeakPolarHBondContact O-CB 3.41Å; A693-H697 PolarHBondContact O-N 3.16Å; V694-H697 PolarHBondContact O-N 2.89Å; L695-H697 VanDerWaalsContact C-N 3.32Å; L695-H697 PolarHBondContact O-N 3Å; H697-G700 PolarHBondContact O-N 3.42Å; H697-A705 HydrophobicContact CB-CB 3.98Å; H697-Y709 HydrophobicContact CB-CE2 4.3Å
698R92.7Very high95.1Very high123 Ų12342.6 Ų42.646%0.46421%0.207SC..Hα-helixtrans-66.5-35.3175.5-70.6179.969.1-175.50.2113.1Y668 V694 L695 G700Y668-R698 HydrophobicContact CE1-CB 4.42Å; V694-R698 WeakPolarHBondContact O-CG 3.39Å; V694-R698 PolarHBondContact O-N 3Å; L695-R698 PolarHBondContact O-N 3.16Å; R698-G700 VanDerWaalsContact C-N 3.28Å
699W94.9Very high95.3Very high70 Ų7042.4 Ų42.427%0.26521%0.205SC..Hα-helixtrans-77.5-12.6178.1-167.56.4000113.1Y668 K669 E672 L695 Y696 K701Y668-W699 VanDerWaalsContact CB-CE3 3.49Å; Y668-W699 HydrophobicContact CD1-CB 3.96Å; Y668-W699 HydrophobicContact CD1-CD2 4.5Å; Y668-W699 HydrophobicContact CD1-CG 4.13Å; Y668-W699 HydrophobicContact CD2-CB 4.33Å; Y668-W699 AromaticContact CD2-CD1 3.53Å; Y668-W699 HydrophobicContact CD2-CD2 4.24Å; Y668-W699 AromaticContact CD2-CG 3.82Å; Y668-W699 HydrophobicContact CD2-CG 3.82Å; Y668-W699 AromaticContact CD2-NE1 3.86Å; Y668-W699 HydrophobicContact CE1-CB 4.27Å; Y668-W699 HydrophobicContact CE2-CG 4.43Å; Y668-W699 HydrophobicContact CG-CB 4Å; Y668-W699 AromaticContact CG-CD1 3.85Å; Y668-W699 AromaticContact CG-CD2 3.82Å; Y668-W699 HydrophobicContact CG-CD2 3.82Å; Y668-W699 HydrophobicContact CG-CE3 4.3Å; Y668-W699 AromaticContact CG-CG 3.65Å; Y668-W699 HydrophobicContact CG-CG 3.65Å; K669-W699 HydrophobicContact CB-CH2 4.35Å; K669-W699 HydrophobicContact CG-CH2 3.63Å; K669-W699 HydrophobicContact CG-CZ2 3.81Å; E672-W699 HydrophobicContact CB-CZ3 4.07Å; E672-W699 HydrophobicContact CG-CZ3 4.46Å; E672-W699 VanDerWaalsContact OE2-CH2 3.23Å; E672-W699 WeakPolarHBondContact OE2-CH2 3.44Å; E672-W699 WeakPolarHBondContact OE2-CZ3 3.33Å; L695-W699 WeakPolarHBondContact O-CB 3.42Å; L695-W699 PolarHBondContact O-N 3.33Å; Y696-W699 HydrophobicContact CD1-CE3 4.09Å; Y696-W699 HydrophobicContact CE1-CE3 4.3Å; Y696-W699 HydrophobicContact CE1-CZ3 4.34Å; Y696-W699 CarbonylContact O-C 3.31Å; Y696-W699 PolarHBondContact O-N 3.32Å; W699-K701 HydrophobicContact CD2-CD 3.94Å; W699-K701 HydrophobicContact CD2-CG 4.4Å; W699-K701 HydrophobicContact CE3-CD 3.69Å; W699-K701 HydrophobicContact CZ3-CD 4.04Å
700G92.3Very high95.3Very high47 Ų4745.9 Ų45.949%0.48522%0.221SC..THydrogen-bonded Turntrans85.67.3-178.200000114.9Y696 H697 R698 L702Y696-G700 PolarHBondContact O-N 2.84Å; H697-G700 PolarHBondContact O-N 3.42Å; R698-G700 VanDerWaalsContact C-N 3.28Å; G700-L702 PolarHBondContact O-N 3.27Å
701K95.1Very high95.3Very high65 Ų6548.7 Ų48.728%0.28324%0.236SC..  trans-80.765.9172.6-70.8176.8168.5-178.20110.3E672 Y696 W699 E703 L704 A705E672-K701 IonicContact OE1-NZ 2.97Å; E672-K701 PolarHBondContact OE1-NZ 2.74Å; E672-K701 IonicContact OE2-NZ 3.88Å; E672-K701 PolarHBondContact OE2-NZ 3.37Å; Y696-K701 HydrophobicContact CD1-CB 4.04Å; Y696-K701 HydrophobicContact CD1-CD 3.61Å; Y696-K701 HydrophobicContact CD1-CG 4.45Å; Y696-K701 HydrophobicContact CE1-CD 3.87Å; Y696-K701 HydrophobicContact CG-CB 4.29Å; Y696-K701 PolarHBondContact O-N 2.94Å; W699-K701 HydrophobicContact CD2-CD 3.94Å; W699-K701 HydrophobicContact CD2-CG 4.4Å; W699-K701 HydrophobicContact CE3-CD 3.69Å; W699-K701 HydrophobicContact CZ3-CD 4.04Å; K701-E703 PolarHBondContact O-N 2.95Å; K701-L704 HydrophobicContact CB-CB 4.28Å; K701-L704 HydrophobicContact CB-CD1 4.21Å; K701-L704 HydrophobicContact CD-CD1 3.93Å; K701-L704 HydrophobicContact CG-CD1 4.44Å; K701-L704 PolarHBondContact O-N 2.87Å; K701-A705 PolarHBondContact O-N 3.17Å
702L93.7Very high95.3Very high24 Ų2446.2 Ų46.213%0.12622%0.223CC..Hα-helixtrans-62-39.4-165-54.5-175.5000114.5G700 A705 K706 L729 L733 L736G700-L702 PolarHBondContact O-N 3.27Å; L702-A705 WeakPolarHBondContact O-CB 3.4Å; L702-A705 PolarHBondContact O-N 2.92Å; L702-K706 PolarHBondContact O-N 3.43Å; L702-L729 HydrophobicContact CB-CD1 4.03Å; L702-L729 HydrophobicContact CD2-CD1 3.65Å; L702-L729 HydrophobicContact CG-CD1 4.31Å; L702-L733 HydrophobicContact CB-CD2 3.77Å; L702-L733 HydrophobicContact CB-CG 4.49Å; L702-L733 HydrophobicContact CD1-CD2 3.83Å; L702-L733 HydrophobicContact CG-CD2 4.46Å; L702-L736 HydrophobicContact CD1-CD1 3.38Å
703E92.3Very high95.3Very high123 Ų12347.9 Ų47.958%0.57523%0.232SC*.Hα-helixtrans-67.5-38.4178-68.6-56.4140.700112.5K701 K706 K707K701-E703 PolarHBondContact O-N 2.95Å; E703-K706 PolarHBondContact O-N 3.4Å; E703-K707 PolarHBondContact O-N 3.42Å
704L95.1Very high95.3Very high68 Ų6856.3 Ų56.336%0.35627%0.268SS..Hα-helixtrans-68.5-38.2174.2-72170000111.3Y696 K701 K707 H708Y696-L704 HydrophobicContact CD1-CB 4.49Å; Y696-L704 HydrophobicContact CD2-CB 3.69Å; Y696-L704 HydrophobicContact CE1-CD1 4.48Å; Y696-L704 HydrophobicContact CE2-CB 3.97Å; Y696-L704 HydrophobicContact CG-CB 3.98Å; K701-L704 HydrophobicContact CB-CB 4.28Å; K701-L704 HydrophobicContact CB-CD1 4.21Å; K701-L704 HydrophobicContact CD-CD1 3.93Å; K701-L704 HydrophobicContact CG-CD1 4.44Å; K701-L704 PolarHBondContact O-N 2.87Å; L704-K707 PolarHBondContact O-N 3.46Å; L704-H708 PolarHBondContact O-CD2 3.3Å; L704-H708 PolarHBondContact O-N 2.87Å; L704-H708 VanDerWaalsContact O-N 3.13Å
705A96Very high95.2Very high0 Ų057.5 Ų57.50%027%0.273CS..Hα-helixtrans-59-48.4173.200000111A693 H697 K701 L702 K707 H708 Y709 L729A693-A705 WeakPolarHBondContact CB-O 3.43Å; A693-A705 WeakPolarHBondContact O-CB 3.39Å; H697-A705 HydrophobicContact CB-CB 3.98Å; K701-A705 PolarHBondContact O-N 3.17Å; L702-A705 WeakPolarHBondContact O-CB 3.4Å; L702-A705 PolarHBondContact O-N 2.92Å; A705-K707 PolarHBondContact O-N 3.12Å; A705-H708 PolarHBondContact O-N 2.99Å; A705-Y709 HydrophobicContact CB-CD2 4.44Å; A705-Y709 HydrophobicContact CB-CE2 4.2Å; A705-Y709 WeakPolarHBondContact O-CD2 3.26Å; A705-Y709 PolarHBondContact O-N 3.13Å; A705-L729 HydrophobicContact CB-CD1 4.49Å; A705-L729 HydrophobicContact CB-CD2 3.74Å
706K95.8Very high95.1Very high70 Ų7060.3 Ų60.330%0.30429%0.288SS..Hα-helixtrans-55.1-51.9176.6174.4175.2179.3-166.10111.6L702 E703 H708 Y709 E710 Y726 L729 L733L702-K706 PolarHBondContact O-N 3.43Å; E703-K706 PolarHBondContact O-N 3.4Å; K706-H708 VanDerWaalsContact C-N 3.3Å; K706-H708 PolarHBondContact O-N 2.96Å; K706-Y709 PolarHBondContact O-N 3.47Å; K706-E710 WeakPolarHBondContact CE-OE1 3.5Å; K706-E710 WeakPolarHBondContact O-CG 3.45Å; K706-E710 PolarHBondContact O-N 2.76Å; K706-Y726 HydrophobicContact CB-CE2 4.29Å; K706-Y726 WeakPolarHBondContact CE-OH 3.36Å; K706-Y726 HydrophobicContact CG-CE2 3.87Å; K706-L729 HydrophobicContact CB-CD2 3.96Å; K706-L733 HydrophobicContact CD-CD1 4.43Å
707K96.2Very high94.9Very high131 Ų13164 Ų6457%0.5731%0.312SS*.Hα-helixtrans-54.4-44.8179.5-178.9-179.4178.4-179.80112.3E703 L704 A705 L711E703-K707 PolarHBondContact O-N 3.42Å; L704-K707 PolarHBondContact O-N 3.46Å; A705-K707 PolarHBondContact O-N 3.12Å; K707-L711 WeakPolarHBondContact O-CB 3.36Å; K707-L711 PolarHBondContact O-N 2.75Å
708H96.3Very high94.8Very high21 Ų2169.8 Ų69.810%0.09734%0.34CS..Hα-helixtrans-78.4-29.8-177.8-79.1-71.6000113.7H689 A693 Y696 L704 A705 K706 L711 S712H689-H708 AromaticContact CE1-ND1 3.85Å; H689-H708 AromaticContact ND1-CE1 3.64Å; H689-H708 AromaticContact ND1-ND1 3.08Å; H689-H708 PolarHBondContact ND1-ND1 2.92Å; A693-H708 HydrophobicContact CB-CB 3.69Å; Y696-H708 AromaticContact CD2-CD2 3.88Å; Y696-H708 AromaticContact CE2-CD2 3.47Å; Y696-H708 VanDerWaalsContact CE2-CD2 3.47Å; Y696-H708 WeakPolarHBondContact CE2-CD2 3.07Å; Y696-H708 AromaticContact CE2-NE2 3.86Å; L704-H708 PolarHBondContact O-CD2 3.3Å; L704-H708 PolarHBondContact O-N 2.87Å; L704-H708 VanDerWaalsContact O-N 3.13Å; A705-H708 PolarHBondContact O-N 2.99Å; K706-H708 VanDerWaalsContact C-N 3.3Å; K706-H708 PolarHBondContact O-N 2.96Å; H708-L711 PolarHBondContact O-N 3.32Å; H708-S712 WeakPolarHBondContact O-CB 3.13Å; H708-S712 PolarHBondContact O-N 3.19Å
709Y97.2Very high94.6Very high1 Ų164.2 Ų64.20%0.00432%0.32CS..Hα-helixtrans-62.7-46.1168.9-77.7-52.6000111.4A693 V694 H697 A705 K706 L711 S712 L713 T722 N725 Y726 L729A693-Y709 HydrophobicContact CB-CD1 3.44Å; A693-Y709 VanDerWaalsContact CB-CD1 3.44Å; A693-Y709 HydrophobicContact CB-CD2 3.75Å; A693-Y709 HydrophobicContact CB-CE1 3.52Å; A693-Y709 HydrophobicContact CB-CE2 3.84Å; A693-Y709 HydrophobicContact CB-CG 3.54Å; V694-Y709 VanDerWaalsContact CA-OH 3.31Å; V694-Y709 WeakPolarHBondContact CA-OH 3.3Å; V694-Y709 HydrophobicContact CG2-CE1 4.04Å; V694-Y709 VanDerWaalsContact CG2-OH 3.32Å; V694-Y709 WeakPolarHBondContact CG2-OH 3.06Å; V694-Y709 PolarHBondContact N-OH 2.68Å; H697-Y709 HydrophobicContact CB-CE2 4.3Å; A705-Y709 HydrophobicContact CB-CD2 4.44Å; A705-Y709 HydrophobicContact CB-CE2 4.2Å; A705-Y709 WeakPolarHBondContact O-CD2 3.26Å; A705-Y709 PolarHBondContact O-N 3.13Å; K706-Y709 PolarHBondContact O-N 3.47Å; Y709-L711 VanDerWaalsContact C-N 3.34Å; Y709-L711 PolarHBondContact O-N 2.98Å; Y709-S712 PolarHBondContact O-N 3.1Å; Y709-L713 WeakPolarHBondContact O-CG 3.46Å; Y709-L713 PolarHBondContact O-N 3.43Å; Y709-T722 HydrophobicContact CD1-CG2 3.78Å; Y709-T722 HydrophobicContact CE1-CG2 4.49Å; Y709-N725 HydrophobicContact CE1-CB 3.75Å; Y709-N725 WeakPolarHBondContact OH-CB 3.41Å; Y709-Y726 AromaticContact CD2-CD2 3.69Å; Y709-Y726 HydrophobicContact CD2-CD2 3.69Å; Y709-Y726 HydrophobicContact CD2-CG 4.26Å; Y709-Y726 AromaticContact CG-CD2 3.89Å; Y709-Y726 HydrophobicContact CG-CD2 3.89Å; Y709-Y726 HydrophobicContact CG-CG 4.05Å; Y709-L729 HydrophobicContact CD2-CD2 3.68Å; Y709-L729 HydrophobicContact CE2-CB 4.25Å; Y709-L729 HydrophobicContact CE2-CD2 3.83Å
710E95.8Very high94.1Very high86 Ų8666.6 Ų66.640%0.40234%0.344SS..Hα-helixtrans-62.2-42.1177-71174.5168.800111.7K706 L713 K714 Y726K706-E710 WeakPolarHBondContact CE-OE1 3.5Å; K706-E710 WeakPolarHBondContact O-CG 3.45Å; K706-E710 PolarHBondContact O-N 2.76Å; E710-L713 PolarHBondContact O-N 3.15Å; E710-K714 VanDerWaalsContact O-CB 3.28Å; E710-K714 WeakPolarHBondContact O-CB 3.14Å; E710-K714 PolarHBondContact O-N 3.4Å; E710-Y726 HydrophobicContact CG-CE1 4.03Å; E710-Y726 PolarHBondContact OE1-OH 3.05Å
711L95.8Very high93.7Very high59 Ų5966.1 Ų66.131%0.30934%0.34SS..Hα-helixtrans-66-40.9176.9-173.659.2000112.3H689 K707 H708 Y709 K714 L715H689-L711 WeakPolarHBondContact CE1-CD2 3.45Å; H689-L711 WeakPolarHBondContact NE2-CD2 3.26Å; K707-L711 WeakPolarHBondContact O-CB 3.36Å; K707-L711 PolarHBondContact O-N 2.75Å; H708-L711 PolarHBondContact O-N 3.32Å; Y709-L711 VanDerWaalsContact C-N 3.34Å; Y709-L711 PolarHBondContact O-N 2.98Å; L711-K714 PolarHBondContact O-N 2.96Å; L711-L715 HydrophobicContact CG-CD1 4.35Å; L711-L715 WeakPolarHBondContact O-CG 3.19Å; L711-L715 PolarHBondContact O-N 3.03Å; L711-L715 VanDerWaalsContact O-N 3.09Å
712S96.3Very high93.6Very high0 Ų063.4 Ų63.40%033%0.329CS..Hα-helixtrans-58.5-51.8174.1-176.10000111.1A686 G690 H708 Y709 K714 L715 D716A686-S712 PolarHBondContact O-OG 2.96Å; G690-S712 PolarHBondContact N-OG 3.42Å; H708-S712 WeakPolarHBondContact O-CB 3.13Å; H708-S712 PolarHBondContact O-N 3.19Å; Y709-S712 PolarHBondContact O-N 3.1Å; S712-K714 VanDerWaalsContact C-N 3.28Å; S712-K714 PolarHBondContact O-N 3.26Å; S712-L715 PolarHBondContact O-N 2.66Å; S712-L715 VanDerWaalsContact O-N 3.11Å; S712-D716 PolarHBondContact O-N 3.48Å
713L95.6Very high93.5Very high35 Ų3569.7 Ų69.718%0.18335%0.351CS..Hα-helixtrans-68.5-25-179.7-67.1171.6000113.4Y709 E710 D716 P717 T722 R723 Y726Y709-L713 WeakPolarHBondContact O-CG 3.46Å; Y709-L713 PolarHBondContact O-N 3.43Å; E710-L713 PolarHBondContact O-N 3.15Å; L713-D716 WeakPolarHBondContact CA-O 3.45Å; L713-D716 CarbonylContact O-C 3.25Å; L713-P717 VanDerWaalsContact O-CA 3.3Å; L713-P717 WeakPolarHBondContact O-CA 3.41Å; L713-T722 HydrophobicContact CD1-CG2 4.5Å; L713-T722 HydrophobicContact CD2-CG2 3.92Å; L713-T722 HydrophobicContact CG-CG2 3.85Å; L713-R723 HydrophobicContact CD2-CB 4.21Å; L713-Y726 HydrophobicContact CD1-CD1 3.97Å
714K96.1Very high93.5Very high177 Ų17768.9 Ų68.977%0.7735%0.35SS*.Hα-helixtrans-70.3-37.7171.8-174.6-179.8-179.6-178.50111.7E710 L711 S712E710-K714 VanDerWaalsContact O-CB 3.28Å; E710-K714 WeakPolarHBondContact O-CB 3.14Å; E710-K714 PolarHBondContact O-N 3.4Å; L711-K714 PolarHBondContact O-N 2.96Å; S712-K714 VanDerWaalsContact C-N 3.28Å; S712-K714 PolarHBondContact O-N 3.26Å
715L94.6Very high93.4Very high66 Ų6668.4 Ų68.435%0.34635%0.348SS..Hα-helixtrans-77.7-38178.6-69.5168.7000111.8N684 A686 L711 S712N684-L715 HydrophobicContact CB-CD2 4.18Å; A686-L715 HydrophobicContact CB-CB 3.8Å; L711-L715 HydrophobicContact CG-CD1 4.35Å; L711-L715 WeakPolarHBondContact O-CG 3.19Å; L711-L715 PolarHBondContact O-N 3.03Å; L711-L715 VanDerWaalsContact O-N 3.09Å; S712-L715 PolarHBondContact O-N 2.66Å; S712-L715 VanDerWaalsContact O-N 3.11Å
716D94.8Very high93.4Very high64 Ų6469.6 Ų69.634%0.34235%0.353SS..  trans-144.9101176.9179.27.7000109.8A686 S712 L713 E718 A719A686-D716 HydrophobicContact CB-CB 3.58Å; S712-D716 PolarHBondContact O-N 3.48Å; L713-D716 WeakPolarHBondContact CA-O 3.45Å; L713-D716 CarbonylContact O-C 3.25Å; D716-E718 PolarHBondContact O-N 3.16Å; D716-E718 PolarHBondContact OD1-N 3.44Å; D716-A719 HydrophobicContact CB-CB 4.17Å; D716-A719 VanDerWaalsContact O-CB 3.25Å; D716-A719 WeakPolarHBondContact O-CB 3.43Å; D716-A719 PolarHBondContact O-N 2.98Å; D716-A719 VanDerWaalsContact O-N 3.12Å; D716-A719 PolarHBondContact OD1-N 3.4Å
717P92.6Very high93.2Very high84 Ų8469.1 Ų69.155%0.54535%0.354SS..THydrogen-bonded Turntrans-59.4-24.7179-26.335.7000114.4L713L713-P717 VanDerWaalsContact O-CA 3.3Å; L713-P717 WeakPolarHBondContact O-CA 3.41Å
718E91Very high93Very high151 Ų15168.2 Ų68.271%0.70635%0.353SS*.THydrogen-bonded Turntrans-100.615.1-178.5-61.7-57.7135.400112.2D716 P720D716-E718 PolarHBondContact O-N 3.16Å; D716-E718 PolarHBondContact OD1-N 3.44Å; E718-P720 VanDerWaalsContact O-CD 3.27Å; E718-P720 WeakPolarHBondContact O-CD 3.45Å
719A88.8Confident92.9Very high6 Ų667.2 Ų67.25%0.0535%0.348CS..  trans-51.6114.6-179.100000111.5D716 G721 T722D716-A719 HydrophobicContact CB-CB 4.17Å; D716-A719 VanDerWaalsContact O-CB 3.25Å; D716-A719 WeakPolarHBondContact O-CB 3.43Å; D716-A719 PolarHBondContact O-N 2.98Å; D716-A719 VanDerWaalsContact O-N 3.12Å; D716-A719 PolarHBondContact OD1-N 3.4Å; A719-G721 PolarHBondContact O-N 2.92Å; A719-T722 HydrophobicContact CB-CG2 4.42Å; A719-T722 WeakPolarHBondContact O-CB 3.46Å; A719-T722 PolarHBondContact O-N 3.24Å; A719-T722 VanDerWaalsContact O-N 3.11Å; A719-T722 PolarHBondContact O-OG1 3.02Å
720P84.3Confident92.7Very high120 Ų12073.2 Ų73.278%0.77937%0.371SS*.THydrogen-bonded Turntrans-56.8130.8-170.1-28.734.9000113.1E718 T722E718-P720 VanDerWaalsContact O-CD 3.27Å; E718-P720 WeakPolarHBondContact O-CD 3.45Å; P720-T722 PolarHBondContact O-N 3.19Å
721G85.3Confident92.4Very high38 Ų3877.7 Ų77.739%0.39238%0.384SS..THydrogen-bonded Turntrans65.6-5.9178.700000115.6A719 N725A719-G721 PolarHBondContact O-N 2.92Å; G721-N725 VanDerWaalsContact O-CB 3.31Å; G721-N725 WeakPolarHBondContact O-CB 3.35Å; G721-N725 PolarHBondContact O-N 3.3Å; G721-N725 PolarHBondContact O-ND2 2.87Å
722T92.1Very high92Very high8 Ų879.3 Ų79.35%0.04939%0.388CS..Hα-helixtrans-71.3-44.4-177.6-62.20000110.7Y709 L713 A719 P720 N725 Y726Y709-T722 HydrophobicContact CD1-CG2 3.78Å; Y709-T722 HydrophobicContact CE1-CG2 4.49Å; L713-T722 HydrophobicContact CD1-CG2 4.5Å; L713-T722 HydrophobicContact CD2-CG2 3.92Å; L713-T722 HydrophobicContact CG-CG2 3.85Å; A719-T722 HydrophobicContact CB-CG2 4.42Å; A719-T722 WeakPolarHBondContact O-CB 3.46Å; A719-T722 PolarHBondContact O-N 3.24Å; A719-T722 VanDerWaalsContact O-N 3.11Å; A719-T722 PolarHBondContact O-OG1 3.02Å; P720-T722 PolarHBondContact O-N 3.19Å; T722-N725 PolarHBondContact O-N 3.01Å; T722-Y726 WeakPolarHBondContact O-CB 3.48Å; T722-Y726 PolarHBondContact O-N 2.81Å
723R92.2Very high91.6Very high155 Ų15580.3 Ų80.359%0.58539%0.394SS*.Hα-helixtrans-63.1-43.6179.9-171.9174.1-177.9167.9-1.8112.2L713 Y726 N727L713-R723 HydrophobicContact CD2-CB 4.21Å; R723-Y726 PolarHBondContact O-N 2.98Å; R723-N727 VanDerWaalsContact O-CG 3.25Å; R723-N727 PolarHBondContact O-N 3.37Å; R723-N727 PolarHBondContact O-ND2 3.43Å
724D92.1Very high91.2Very high107 Ų10782.2 Ų82.257%0.57240%0.404SS*.Hα-helixtrans-65.4-47.1179.1-62.3-33.5000111.3Y726 N727 M728D724-Y726 VanDerWaalsContact C-N 3.27Å; D724-Y726 PolarHBondContact O-N 3.41Å; D724-N727 WeakPolarHBondContact O-CB 3.36Å; D724-N727 PolarHBondContact O-N 3.49Å; D724-M728 WeakPolarHBondContact O-CG 3.38Å; D724-M728 PolarHBondContact O-N 3Å
725N93.4Very high90.6Very high57 Ų5780.3 Ų80.331%0.30540%0.398SS..Hα-helixtrans-61-36.8175.3-76.2-42.1000112.3V694 Y709 G721 T722 M728 L729V694-N725 HydrophobicContact CG2-CB 4.44Å; Y709-N725 HydrophobicContact CE1-CB 3.75Å; Y709-N725 WeakPolarHBondContact OH-CB 3.41Å; G721-N725 VanDerWaalsContact O-CB 3.31Å; G721-N725 WeakPolarHBondContact O-CB 3.35Å; G721-N725 PolarHBondContact O-N 3.3Å; G721-N725 PolarHBondContact O-ND2 2.87Å; T722-N725 PolarHBondContact O-N 3.01Å; N725-M728 PolarHBondContact O-N 2.89Å; N725-L729 PolarHBondContact O-N 2.98Å; N725-L729 VanDerWaalsContact O-N 3.09Å
726Y95Very high90Very high25 Ų2581.1 Ų81.110%0.09840%0.402CS..Hα-helixtrans-68.8-40.8175.9-174.6-143.3000112.1K706 Y709 E710 L713 T722 R723 D724 M728 L729 R730K706-Y726 HydrophobicContact CB-CE2 4.29Å; K706-Y726 WeakPolarHBondContact CE-OH 3.36Å; K706-Y726 HydrophobicContact CG-CE2 3.87Å; Y709-Y726 AromaticContact CD2-CD2 3.69Å; Y709-Y726 HydrophobicContact CD2-CD2 3.69Å; Y709-Y726 HydrophobicContact CD2-CG 4.26Å; Y709-Y726 AromaticContact CG-CD2 3.89Å; Y709-Y726 HydrophobicContact CG-CD2 3.89Å; Y709-Y726 HydrophobicContact CG-CG 4.05Å; E710-Y726 HydrophobicContact CG-CE1 4.03Å; E710-Y726 PolarHBondContact OE1-OH 3.05Å; L713-Y726 HydrophobicContact CD1-CD1 3.97Å; T722-Y726 WeakPolarHBondContact O-CB 3.48Å; T722-Y726 PolarHBondContact O-N 2.81Å; R723-Y726 PolarHBondContact O-N 2.98Å; D724-Y726 VanDerWaalsContact C-N 3.27Å; D724-Y726 PolarHBondContact O-N 3.41Å; Y726-M728 VanDerWaalsContact C-N 3.29Å; Y726-M728 PolarHBondContact O-N 3.39Å; Y726-L729 HydrophobicContact CD2-CB 4.47Å; Y726-L729 HydrophobicContact CD2-CD2 4.2Å; Y726-L729 HydrophobicContact CE2-CD2 4.37Å; Y726-L729 WeakPolarHBondContact O-CB 3.25Å; Y726-L729 PolarHBondContact O-N 3.5Å; Y726-L729 VanDerWaalsContact O-N 3.15Å; Y726-R730 HydrophobicContact CD2-CG 4.23Å; Y726-R730 HydrophobicContact CE2-CG 3.83Å; Y726-R730 WeakPolarHBondContact O-CG 3.36Å; Y726-R730 PolarHBondContact O-N 3.35Å
727N92.5Very high89.3Confident60 Ų6085 Ų8532%0.32142%0.416SS..Hα-helixtrans-60.8-39.4174.6-72.6-27.6000111.7R723 D724 R730 R731R723-N727 VanDerWaalsContact O-CG 3.25Å; R723-N727 PolarHBondContact O-N 3.37Å; R723-N727 PolarHBondContact O-ND2 3.43Å; D724-N727 WeakPolarHBondContact O-CB 3.36Å; D724-N727 PolarHBondContact O-N 3.49Å; N727-R730 PolarHBondContact O-N 3.22Å; N727-R731 WeakPolarHBondContact O-CG 3.39Å; N727-R731 PolarHBondContact O-N 3.33Å; N727-R731 VanDerWaalsContact O-N 3.1Å
728M92.4Very high88.2Confident113 Ų11388.9 Ų88.956%0.55743%0.427SS*.Hα-helixtrans-61.9-44173.3-68.617668.900111.9D724 N725 Y726 R730 R731 K732D724-M728 WeakPolarHBondContact O-CG 3.38Å; D724-M728 PolarHBondContact O-N 3Å; N725-M728 PolarHBondContact O-N 2.89Å; Y726-M728 VanDerWaalsContact C-N 3.29Å; Y726-M728 PolarHBondContact O-N 3.39Å; M728-R730 PolarHBondContact O-N 3.27Å; M728-R731 PolarHBondContact O-N 3.47Å; M728-K732 PolarHBondContact O-N 2.81Å; M728-K732 VanDerWaalsContact O-N 3.15Å
729L93.4Very high86.8Confident0 Ų085.7 Ų85.70%042%0.421CS..Hα-helixtrans-60.8-44.2175.6177.867.4000111.5L702 A705 K706 Y709 N725 Y726 K732 L733L702-L729 HydrophobicContact CB-CD1 4.03Å; L702-L729 HydrophobicContact CD2-CD1 3.65Å; L702-L729 HydrophobicContact CG-CD1 4.31Å; A705-L729 HydrophobicContact CB-CD1 4.49Å; A705-L729 HydrophobicContact CB-CD2 3.74Å; K706-L729 HydrophobicContact CB-CD2 3.96Å; Y709-L729 HydrophobicContact CD2-CD2 3.68Å; Y709-L729 HydrophobicContact CE2-CB 4.25Å; Y709-L729 HydrophobicContact CE2-CD2 3.83Å; N725-L729 PolarHBondContact O-N 2.98Å; N725-L729 VanDerWaalsContact O-N 3.09Å; Y726-L729 HydrophobicContact CD2-CB 4.47Å; Y726-L729 HydrophobicContact CD2-CD2 4.2Å; Y726-L729 HydrophobicContact CE2-CD2 4.37Å; Y726-L729 WeakPolarHBondContact O-CB 3.25Å; Y726-L729 PolarHBondContact O-N 3.5Å; Y726-L729 VanDerWaalsContact O-N 3.15Å; L729-K732 WeakPolarHBondContact O-CB 3.48Å; L729-K732 PolarHBondContact O-N 3.29Å; L729-L733 HydrophobicContact CD1-CD1 4.35Å; L729-L733 HydrophobicContact CD1-CG 4.34Å; L729-L733 HydrophobicContact CD2-CD1 4.42Å; L729-L733 HydrophobicContact CG-CD1 3.98Å; L729-L733 HydrophobicContact CG-CG 4.38Å; L729-L733 WeakPolarHBondContact O-CG 3.49Å; L729-L733 PolarHBondContact O-N 3Å
730R91.9Very high85.2Confident127 Ų12790.2 Ų90.248%0.47945%0.448SS..Hα-helixtrans-59.3-48.5179.2-74.7-178.366-176.12.2111.7Y726 N727 M728 K732 L733 D734Y726-R730 HydrophobicContact CD2-CG 4.23Å; Y726-R730 HydrophobicContact CE2-CG 3.83Å; Y726-R730 WeakPolarHBondContact O-CG 3.36Å; Y726-R730 PolarHBondContact O-N 3.35Å; N727-R730 PolarHBondContact O-N 3.22Å; M728-R730 PolarHBondContact O-N 3.27Å; R730-K732 VanDerWaalsContact C-N 3.26Å; R730-K732 PolarHBondContact O-N 2.57Å; R730-L733 PolarHBondContact O-N 3.31Å; R730-D734 VanDerWaalsContact O-CG 3.23Å; R730-D734 PolarHBondContact O-N 3.4Å
731R90.1Very high83.7Confident180 Ų18094 Ų9468%0.67947%0.473SS*.Hα-helixtrans-56.4-41.6175.4-69.6178.1-173.5174.72.7111.9N727 M728 D734 Q735N727-R731 WeakPolarHBondContact O-CG 3.39Å; N727-R731 PolarHBondContact O-N 3.33Å; N727-R731 VanDerWaalsContact O-N 3.1Å; M728-R731 PolarHBondContact O-N 3.47Å; R731-D734 PolarHBondContact O-N 3.07Å; R731-Q735 WeakPolarHBondContact O-CG 3.26Å; R731-Q735 PolarHBondContact O-N 2.93Å
732K87.8Confident83.6Confident92 Ų9296.8 Ų96.840%0.448%0.477SS..Hα-helixtrans-67.2-41.8178.1-172175-177.4176.30112.5M728 L729 R730 D734 Q735 L736M728-K732 PolarHBondContact O-N 2.81Å; M728-K732 VanDerWaalsContact O-N 3.15Å; L729-K732 WeakPolarHBondContact O-CB 3.48Å; L729-K732 PolarHBondContact O-N 3.29Å; R730-K732 VanDerWaalsContact C-N 3.26Å; R730-K732 PolarHBondContact O-N 2.57Å; K732-D734 VanDerWaalsContact C-N 3.34Å; K732-Q735 PolarHBondContact O-N 3.3Å; K732-L736 HydrophobicContact CG-CD1 4.38Å; K732-L736 WeakPolarHBondContact O-CG 3.46Å; K732-L736 PolarHBondContact O-N 3.09Å
733L88.2Confident83.2Confident22 Ų22101.5 Ų101.512%0.11550%0.499CS..Hα-helixtrans-63.6-40.4174.4-76.4170.7000111.6L702 K706 L729 R730 L736 K737L702-L733 HydrophobicContact CB-CD2 3.77Å; L702-L733 HydrophobicContact CB-CG 4.49Å; L702-L733 HydrophobicContact CD1-CD2 3.83Å; L702-L733 HydrophobicContact CG-CD2 4.46Å; K706-L733 HydrophobicContact CD-CD1 4.43Å; L729-L733 HydrophobicContact CD1-CD1 4.35Å; L729-L733 HydrophobicContact CD1-CG 4.34Å; L729-L733 HydrophobicContact CD2-CD1 4.42Å; L729-L733 HydrophobicContact CG-CD1 3.98Å; L729-L733 HydrophobicContact CG-CG 4.38Å; L729-L733 WeakPolarHBondContact O-CG 3.49Å; L729-L733 PolarHBondContact O-N 3Å; R730-L733 PolarHBondContact O-N 3.31Å; L733-L736 PolarHBondContact O-N 3.37Å; L733-K737 WeakPolarHBondContact O-CG 3.35Å; L733-K737 PolarHBondContact O-N 3.4Å; L733-K737 VanDerWaalsContact O-N 3.1Å
734D86.7Confident82.7Confident74 Ų7498.5 Ų98.540%0.39649%0.494SS..Hα-helixtrans-65.6-43.1176.7-65.8-26.3000110.7R730 R731 K732 L736 K737 H738R730-D734 VanDerWaalsContact O-CG 3.23Å; R730-D734 PolarHBondContact O-N 3.4Å; R731-D734 PolarHBondContact O-N 3.07Å; K732-D734 VanDerWaalsContact C-N 3.34Å; D734-L736 VanDerWaalsContact C-N 3.35Å; D734-L736 PolarHBondContact O-N 3.33Å; D734-K737 PolarHBondContact O-N 3.3Å; D734-H738 PolarHBondContact O-N 3.26Å; D734-H738 PolarHBondContact O-ND1 3.27Å
735Q84.1Confident82.1Confident137 Ų13798 Ų9864%0.6449%0.49SS*.Hα-helixtrans-58.3-43.2172.9-75.7173.4-9.400112.7R731 K732 K737 H738 S739R731-Q735 WeakPolarHBondContact O-CG 3.26Å; R731-Q735 PolarHBondContact O-N 2.93Å; K732-Q735 PolarHBondContact O-N 3.3Å; Q735-K737 VanDerWaalsContact C-N 3.3Å; Q735-K737 PolarHBondContact O-N 3.06Å; Q735-H738 PolarHBondContact O-N 3.32Å; Q735-S739 PolarHBondContact O-N 2.81Å; Q735-S739 VanDerWaalsContact O-N 3.14Å; Q735-S739 PolarHBondContact O-OG 2.82Å
736L82.2Confident81.4Confident84 Ų84100.6 Ų100.644%0.4450%0.501SS..Hα-helixtrans-64.6-33.2178.5-75164.6000112.8L702 K732 L733 D734 H738 S739 T740L702-L736 HydrophobicContact CD1-CD1 3.38Å; K732-L736 HydrophobicContact CG-CD1 4.38Å; K732-L736 WeakPolarHBondContact O-CG 3.46Å; K732-L736 PolarHBondContact O-N 3.09Å; L733-L736 PolarHBondContact O-N 3.37Å; D734-L736 VanDerWaalsContact C-N 3.35Å; D734-L736 PolarHBondContact O-N 3.33Å; L736-H738 VanDerWaalsContact C-N 3.35Å; L736-S739 WeakPolarHBondContact CA-OG 3.38Å; L736-S739 PolarHBondContact O-OG 2.89Å; L736-T740 PolarHBondContact O-OG1 2.85Å
737K78.4Confident80.5Confident146 Ų146105.6 Ų105.664%0.63553%0.528SS*.Hα-helixtrans-71.5-26.9174.4-72.7175.7-179.6-179.50113.7L733 D734 Q735L733-K737 WeakPolarHBondContact O-CG 3.35Å; L733-K737 PolarHBondContact O-N 3.4Å; L733-K737 VanDerWaalsContact O-N 3.1Å; D734-K737 PolarHBondContact O-N 3.3Å; Q735-K737 VanDerWaalsContact C-N 3.3Å; Q735-K737 PolarHBondContact O-N 3.06Å
738H71.5Confident79.7Confident165 Ų165108.9 Ų108.976%0.76454%0.543SS*.Hα-helixtrans-93.2-4.8179-67.570.2000113D734 Q735 L736D734-H738 PolarHBondContact O-N 3.26Å; D734-H738 PolarHBondContact O-ND1 3.27Å; Q735-H738 PolarHBondContact O-N 3.32Å; L736-H738 VanDerWaalsContact C-N 3.35Å
739S60.8Low78.7Confident84 Ų84108.5 Ų108.559%0.58754%0.542SS*.SBendtrans-1114.9179.343.90000113.5Q735 L736Q735-S739 PolarHBondContact O-N 2.81Å; Q735-S739 VanDerWaalsContact O-N 3.14Å; Q735-S739 PolarHBondContact O-OG 2.82Å; L736-S739 WeakPolarHBondContact CA-OG 3.38Å; L736-S739 PolarHBondContact O-OG 2.89Å
740T55.3Low77.5Confident100 Ų100117.6 Ų117.661%0.61359%0.587SS**  trans-96.6119.4167.217.80000108L736L736-T740 PolarHBondContact O-OG1 2.85Å
741P52.9Low76.2Confident200 Ų200116.7 Ų116.7100%1.29960%0.597SS**  trans-67.50-178.326.8-32.9000113.5

Retrieved 741 of 741 residues in 3294.4 ms (Link to these results)