A0A087Y3C3_POEFO Loading...

Lysosomal cobalamin transport escort protein LMBD1

AlphaFold DB , UniProt , Accession A0A087Y3C3, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 538 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	41	Very low	49.7	Very low	197 Å²	197	94.7 Å²	94.7	97%	0.97	55%	0.552	S	S	*	*				0	-52.8	0	-77.8	-173.3	-86.8	0	0	112.9	A3 Q4 S5	M1-A3 PolarHBondContact O-N 3.18Å; M1-Q4 PolarHBondContact O-N 3.2Å; M1-Q4 VanDerWaalsContact O-N 3.14Å; M1-S5 PolarHBondContact O-N 2.91Å; M1-S5 VanDerWaalsContact O-N 3.1Å
2	A	38	Very low	51.4	Low	77 Å²	77	93.9 Å²	93.9	64%	0.636	54%	0.542	S	S	*	.	H	α-helix	trans	-61.8	-34.9	177.4	0	0	0	0	0	114.9	Q4 S5 L6	A2-Q4 VanDerWaalsContact C-N 3.35Å; A2-S5 PolarHBondContact O-OG 3.15Å; A2-L6 WeakPolarHBondContact O-CB 3.45Å; A2-L6 PolarHBondContact O-N 3.27Å; A2-L6 VanDerWaalsContact O-N 3.16Å
3	A	37.6	Very low	52.6	Low	74 Å²	74	88.9 Å²	88.9	61%	0.612	52%	0.524	S	S	*	.	H	α-helix	trans	-70.1	-30.2	175	0	0	0	0	0	113.1	M1 L7	M1-A3 PolarHBondContact O-N 3.18Å; A3-L7 WeakPolarHBondContact O-CB 3.41Å; A3-L7 PolarHBondContact O-N 3.15Å; A3-L7 VanDerWaalsContact O-N 3.15Å
4	Q	37.8	Very low	53.9	Low	144 Å²	144	95.4 Å²	95.4	67%	0.673	54%	0.535	S	S	*	.	H	α-helix	trans	-76.8	-36.8	177.3	-84.6	168.5	-36.7	0	0	111.8	M1 A2 L7 S8	M1-Q4 PolarHBondContact O-N 3.2Å; M1-Q4 VanDerWaalsContact O-N 3.14Å; A2-Q4 VanDerWaalsContact C-N 3.35Å; Q4-L7 PolarHBondContact O-N 3.03Å; Q4-S8 PolarHBondContact O-N 3.5Å; Q4-S8 PolarHBondContact O-OG 3.34Å
5	S	48.6	Very low	55.6	Low	53 Å²	53	92.9 Å²	92.9	37%	0.371	53%	0.526	S	S	.	.	H	α-helix	trans	-67.9	-37.2	174.5	59	0	0	0	0	112.1	M1 A2 S8 E9	M1-S5 PolarHBondContact O-N 2.91Å; M1-S5 VanDerWaalsContact O-N 3.1Å; A2-S5 PolarHBondContact O-OG 3.15Å; S5-S8 WeakPolarHBondContact CA-OG 3.48Å; S5-S8 PolarHBondContact O-N 2.99Å; S5-S8 PolarHBondContact O-OG 3.38Å; S5-E9 WeakPolarHBondContact O-CB 3.41Å; S5-E9 WeakPolarHBondContact O-CG 3.26Å; S5-E9 PolarHBondContact O-N 3.01Å
6	L	47.5	Very low	57	Low	98 Å²	98	89.5 Å²	89.5	51%	0.513	51%	0.506	S	S	.	.	H	α-helix	trans	-69.5	-36	176.9	-150.9	149	0	0	0	111.8	A2 S10	A2-L6 WeakPolarHBondContact O-CB 3.45Å; A2-L6 PolarHBondContact O-N 3.27Å; A2-L6 VanDerWaalsContact O-N 3.16Å; L6-S10 VanDerWaalsContact O-CB 3.28Å; L6-S10 WeakPolarHBondContact O-CB 3.31Å; L6-S10 PolarHBondContact O-N 3.11Å; L6-S10 PolarHBondContact O-OG 3.25Å
7	L	48.1	Very low	58.1	Low	113 Å²	113	87.8 Å²	87.8	59%	0.592	49%	0.491	S	S	*	.	H	α-helix	trans	-65.7	-44.1	170	-105.7	149.3	0	0	0	112.1	A3 Q4 S10 V11	A3-L7 WeakPolarHBondContact O-CB 3.41Å; A3-L7 PolarHBondContact O-N 3.15Å; A3-L7 VanDerWaalsContact O-N 3.15Å; Q4-L7 PolarHBondContact O-N 3.03Å; L7-S10 WeakPolarHBondContact CA-OG 3.35Å; L7-S10 PolarHBondContact O-OG 3.43Å; L7-S10 VanDerWaalsContact O-OG 3.06Å; L7-V11 VanDerWaalsContact O-CB 3.3Å; L7-V11 WeakPolarHBondContact O-CB 3.5Å; L7-V11 WeakPolarHBondContact O-CG2 3.42Å; L7-V11 PolarHBondContact O-N 3.09Å
8	S	56.7	Low	59.5	Low	60 Å²	60	86.9 Å²	86.9	42%	0.42	49%	0.489	S	S	.	.	H	α-helix	trans	-66.1	-41.5	177.5	55.9	0	0	0	0	112.6	Q4 S5 V11 I12	Q4-S8 PolarHBondContact O-N 3.5Å; Q4-S8 PolarHBondContact O-OG 3.34Å; S5-S8 WeakPolarHBondContact CA-OG 3.48Å; S5-S8 PolarHBondContact O-N 2.99Å; S5-S8 PolarHBondContact O-OG 3.38Å; S8-V11 PolarHBondContact O-N 3.17Å; S8-I12 WeakPolarHBondContact O-CB 3.42Å; S8-I12 WeakPolarHBondContact O-CD1 3.31Å; S8-I12 WeakPolarHBondContact O-CG1 3.48Å; S8-I12 PolarHBondContact O-N 3.08Å
9	E	61.3	Low	60.9	Low	92 Å²	92	86.9 Å²	86.9	43%	0.43	49%	0.491	S	S	.	.	H	α-helix	trans	-71.1	-38.4	-179.2	-72.8	179.1	-155.2	0	0	112.3	S5 I12 G13 Y72	S5-E9 WeakPolarHBondContact O-CB 3.41Å; S5-E9 WeakPolarHBondContact O-CG 3.26Å; S5-E9 PolarHBondContact O-N 3.01Å; E9-I12 PolarHBondContact O-N 3.49Å; E9-G13 PolarHBondContact O-N 2.87Å; E9-Y72 PolarHBondContact OE2-OH 2.88Å
10	S	60.5	Low	62.1	Low	47 Å²	47	83.8 Å²	83.8	33%	0.329	47%	0.473	S	S	.	.	H	α-helix	trans	-66.8	-42.5	173.2	56.8	0	0	0	0	112.2	L6 L7 I12 G13 W14	L6-S10 VanDerWaalsContact O-CB 3.28Å; L6-S10 WeakPolarHBondContact O-CB 3.31Å; L6-S10 PolarHBondContact O-N 3.11Å; L6-S10 PolarHBondContact O-OG 3.25Å; L7-S10 WeakPolarHBondContact CA-OG 3.35Å; L7-S10 PolarHBondContact O-OG 3.43Å; L7-S10 VanDerWaalsContact O-OG 3.06Å; S10-I12 VanDerWaalsContact C-N 3.31Å; S10-I12 PolarHBondContact O-N 3.39Å; S10-G13 PolarHBondContact O-N 2.93Å; S10-W14 PolarHBondContact O-N 3.04Å
11	V	69.8	Low	63.3	Low	87 Å²	87	82.3 Å²	82.3	53%	0.527	46%	0.464	S	S	.	.	H	α-helix	trans	-61	-40.7	175.6	169.8	0	0	0	0	111.1	L7 S8 S15	L7-V11 VanDerWaalsContact O-CB 3.3Å; L7-V11 WeakPolarHBondContact O-CB 3.5Å; L7-V11 WeakPolarHBondContact O-CG2 3.42Å; L7-V11 PolarHBondContact O-N 3.09Å; S8-V11 PolarHBondContact O-N 3.17Å; V11-S15 VanDerWaalsContact O-CB 3.27Å; V11-S15 WeakPolarHBondContact O-CB 3.34Å; V11-S15 PolarHBondContact O-N 3.43Å; V11-S15 PolarHBondContact O-OG 2.94Å
12	I	70.4	Confident	65.7	Low	85 Å²	85	77.9 Å²	77.9	44%	0.436	44%	0.444	S	S	.	.	H	α-helix	trans	-61.5	-48	174.5	-69.4	162.1	0	0	0	110.4	S8 E9 S10 W14 S15 I16 F363	S8-I12 WeakPolarHBondContact O-CB 3.42Å; S8-I12 WeakPolarHBondContact O-CD1 3.31Å; S8-I12 WeakPolarHBondContact O-CG1 3.48Å; S8-I12 PolarHBondContact O-N 3.08Å; E9-I12 PolarHBondContact O-N 3.49Å; S10-I12 VanDerWaalsContact C-N 3.31Å; S10-I12 PolarHBondContact O-N 3.39Å; I12-W14 PolarHBondContact O-N 3.48Å; I12-S15 PolarHBondContact O-N 3.49Å; I12-S15 PolarHBondContact O-OG 3.48Å; I12-I16 HydrophobicContact CG2-CD1 3.78Å; I12-I16 WeakPolarHBondContact O-CG1 3.46Å; I12-I16 PolarHBondContact O-N 2.77Å; I12-F363 HydrophobicContact CG2-CE1 4.42Å
13	G	66.6	Low	68.1	Low	29 Å²	29	78.6 Å²	78.6	30%	0.299	44%	0.44	S	S	.	.	H	α-helix	trans	-58.4	-48.5	177.6	0	0	0	0	0	113.8	E9 S10 S15 I16 F17	E9-G13 PolarHBondContact O-N 2.87Å; S10-G13 PolarHBondContact O-N 2.93Å; G13-S15 VanDerWaalsContact C-N 3.33Å; G13-S15 PolarHBondContact O-N 2.86Å; G13-I16 PolarHBondContact O-N 3.26Å; G13-F17 PolarHBondContact O-N 3.5Å
14	W	71.1	Confident	70.6	Confident	180 Å²	180	75.9 Å²	75.9	68%	0.682	42%	0.415	S	S	*	.	H	α-helix	trans	-65.3	-35.6	177.1	-73.2	111.7	0	0	0	112.5	S10 I12 T18	S10-W14 PolarHBondContact O-N 3.04Å; I12-W14 PolarHBondContact O-N 3.48Å; W14-T18 WeakPolarHBondContact O-CB 3.41Å; W14-T18 PolarHBondContact O-N 3.06Å; W14-T18 PolarHBondContact O-OG1 2.93Å
15	S	78.4	Confident	73.2	Confident	58 Å²	58	72.5 Å²	72.5	41%	0.406	40%	0.401	S	S	.	.	H	α-helix	trans	-63.9	-43.5	175.3	78	0	0	0	0	111.8	V11 I12 G13 T18 V19	V11-S15 VanDerWaalsContact O-CB 3.27Å; V11-S15 WeakPolarHBondContact O-CB 3.34Å; V11-S15 PolarHBondContact O-N 3.43Å; V11-S15 PolarHBondContact O-OG 2.94Å; I12-S15 PolarHBondContact O-N 3.49Å; I12-S15 PolarHBondContact O-OG 3.48Å; G13-S15 VanDerWaalsContact C-N 3.33Å; G13-S15 PolarHBondContact O-N 2.86Å; S15-T18 PolarHBondContact O-N 3.41Å; S15-V19 VanDerWaalsContact O-CG2 3.31Å; S15-V19 WeakPolarHBondContact O-CG2 3.48Å; S15-V19 PolarHBondContact O-N 3.25Å
16	I	78.2	Confident	75.3	Confident	38 Å²	38	72.3 Å²	72.3	20%	0.195	40%	0.403	C	S	.	.	H	α-helix	trans	-64.5	-46.6	177.9	-67.6	164.5	0	0	0	110.2	I12 G13 T18 V19 V20 F363 P364	I12-I16 HydrophobicContact CG2-CD1 3.78Å; I12-I16 WeakPolarHBondContact O-CG1 3.46Å; I12-I16 PolarHBondContact O-N 2.77Å; G13-I16 PolarHBondContact O-N 3.26Å; I16-T18 VanDerWaalsContact C-N 3.3Å; I16-T18 PolarHBondContact O-N 3.37Å; I16-V19 PolarHBondContact O-N 3Å; I16-V20 HydrophobicContact CG2-CG2 4.33Å; I16-V20 VanDerWaalsContact O-CG2 3.22Å; I16-V20 WeakPolarHBondContact O-CG2 3.48Å; I16-V20 PolarHBondContact O-N 3.11Å; I16-F363 HydrophobicContact CD1-CE1 3.47Å; I16-F363 VanDerWaalsContact CD1-CE1 3.47Å; I16-F363 HydrophobicContact CD1-CZ 3.79Å; I16-P364 HydrophobicContact CD1-CB 4.25Å; I16-P364 HydrophobicContact CD1-CG 4.26Å
17	F	75.9	Confident	77.3	Confident	60 Å²	60	70.3 Å²	70.3	26%	0.263	39%	0.39	S	S	.	.	H	α-helix	trans	-58.6	-42.8	176.9	-177.2	-100.3	0	0	0	112.1	G13 V20 L21 V65	G13-F17 PolarHBondContact O-N 3.5Å; F17-V20 PolarHBondContact O-N 2.97Å; F17-L21 HydrophobicContact CE1-CD1 4.24Å; F17-L21 WeakPolarHBondContact O-CB 3.39Å; F17-L21 PolarHBondContact O-N 3.41Å; F17-V65 HydrophobicContact CD2-CG2 4.38Å
18	T	83.6	Confident	79.4	Confident	73 Å²	73	65 Å²	65	45%	0.448	36%	0.362	S	S	.	.	H	α-helix	trans	-63.1	-44	177	-55.9	0	0	0	0	111.6	W14 S15 I16 V20 L21 L22	W14-T18 WeakPolarHBondContact O-CB 3.41Å; W14-T18 PolarHBondContact O-N 3.06Å; W14-T18 PolarHBondContact O-OG1 2.93Å; S15-T18 PolarHBondContact O-N 3.41Å; I16-T18 VanDerWaalsContact C-N 3.3Å; I16-T18 PolarHBondContact O-N 3.37Å; T18-V20 VanDerWaalsContact C-N 3.35Å; T18-V20 PolarHBondContact O-N 3.4Å; T18-L21 PolarHBondContact O-N 3.35Å; T18-L22 WeakPolarHBondContact O-CG 3.48Å; T18-L22 PolarHBondContact O-N 3.01Å
19	V	86.8	Confident	81.1	Confident	87 Å²	87	67.9 Å²	67.9	53%	0.527	36%	0.364	S	S	.	.	H	α-helix	trans	-61	-44.6	176	170.2	0	0	0	0	110.8	S15 I16 L21 L22 V23	S15-V19 VanDerWaalsContact O-CG2 3.31Å; S15-V19 WeakPolarHBondContact O-CG2 3.48Å; S15-V19 PolarHBondContact O-N 3.25Å; I16-V19 PolarHBondContact O-N 3Å; V19-L21 VanDerWaalsContact C-N 3.34Å; V19-L21 PolarHBondContact O-N 3.07Å; V19-L22 PolarHBondContact O-N 2.81Å; V19-V23 HydrophobicContact CG1-CG2 4.5Å; V19-V23 WeakPolarHBondContact O-CG2 3.45Å; V19-V23 PolarHBondContact O-N 3.39Å
20	V	84.9	Confident	82.5	Confident	23 Å²	23	68.9 Å²	68.9	14%	0.139	37%	0.371	C	S	.	.	H	α-helix	trans	-63.2	-42.4	178.8	174.5	0	0	0	0	111	I16 F17 T18 L22 V23 I24 A61 Y367	I16-V20 HydrophobicContact CG2-CG2 4.33Å; I16-V20 VanDerWaalsContact O-CG2 3.22Å; I16-V20 WeakPolarHBondContact O-CG2 3.48Å; I16-V20 PolarHBondContact O-N 3.11Å; F17-V20 PolarHBondContact O-N 2.97Å; T18-V20 VanDerWaalsContact C-N 3.35Å; T18-V20 PolarHBondContact O-N 3.4Å; V20-L22 VanDerWaalsContact C-N 3.34Å; V20-L22 PolarHBondContact O-N 2.96Å; V20-V23 PolarHBondContact O-N 3.4Å; V20-I24 HydrophobicContact CG1-CD1 3.88Å; V20-I24 HydrophobicContact CG1-CG1 4.41Å; V20-I24 WeakPolarHBondContact O-CG1 3.1Å; V20-I24 PolarHBondContact O-N 3.46Å; V20-A61 HydrophobicContact CG1-CB 4.29Å; V20-Y367 HydrophobicContact CB-CE1 4.37Å; V20-Y367 HydrophobicContact CG1-CE1 4.23Å; V20-Y367 WeakPolarHBondContact CG1-OH 3.46Å; V20-Y367 HydrophobicContact CG2-CD1 4.49Å; V20-Y367 HydrophobicContact CG2-CE1 3.45Å; V20-Y367 VanDerWaalsContact CG2-CE1 3.45Å
21	L	87.1	Confident	83.8	Confident	54 Å²	54	67.2 Å²	67.2	28%	0.283	36%	0.358	S	S	.	.	H	α-helix	trans	-60.8	-42.8	176.2	-173.9	144.2	0	0	0	111.7	F17 T18 V19 I24 L25 I58	F17-L21 HydrophobicContact CE1-CD1 4.24Å; F17-L21 WeakPolarHBondContact O-CB 3.39Å; F17-L21 PolarHBondContact O-N 3.41Å; T18-L21 PolarHBondContact O-N 3.35Å; V19-L21 VanDerWaalsContact C-N 3.34Å; V19-L21 PolarHBondContact O-N 3.07Å; L21-I24 PolarHBondContact O-N 3.18Å; L21-L25 HydrophobicContact CD2-CD1 3.67Å; L21-L25 HydrophobicContact CD2-CG 4.35Å; L21-L25 WeakPolarHBondContact O-CG 3.42Å; L21-L25 PolarHBondContact O-N 3.19Å; L21-I58 HydrophobicContact CD1-CD1 4.25Å; L21-I58 HydrophobicContact CG-CD1 4.46Å
22	L	90.3	Very high	84.8	Confident	104 Å²	104	63.1 Å²	63.1	55%	0.545	33%	0.333	S	S	.	.	H	α-helix	trans	-63.6	-41.1	175	-70.8	176.1	0	0	0	112.3	T18 V19 V20 L25 A26	T18-L22 WeakPolarHBondContact O-CG 3.48Å; T18-L22 PolarHBondContact O-N 3.01Å; V19-L22 PolarHBondContact O-N 2.81Å; V20-L22 VanDerWaalsContact C-N 3.34Å; V20-L22 PolarHBondContact O-N 2.96Å; L22-L25 PolarHBondContact O-N 2.96Å; L22-A26 WeakPolarHBondContact O-CB 3.38Å; L22-A26 PolarHBondContact O-N 3.45Å
23	V	89.6	Confident	85.7	Confident	91 Å²	91	65.9 Å²	65.9	55%	0.552	34%	0.338	S	S	*	.	H	α-helix	trans	-63.4	-42.1	176.2	171.3	0	0	0	0	111	V19 V20 A26 F27	V19-V23 HydrophobicContact CG1-CG2 4.5Å; V19-V23 WeakPolarHBondContact O-CG2 3.45Å; V19-V23 PolarHBondContact O-N 3.39Å; V20-V23 PolarHBondContact O-N 3.4Å; V23-A26 PolarHBondContact O-N 2.85Å; V23-F27 VanDerWaalsContact O-CB 3.31Å; V23-F27 WeakPolarHBondContact O-CB 3.46Å; V23-F27 PolarHBondContact O-N 2.72Å
24	I	90.1	Very high	86.8	Confident	18 Å²	18	70.3 Å²	70.3	9%	0.092	35%	0.349	C	S	.	.	H	α-helix	trans	-60.9	-47.9	175.6	-71.3	167.5	0	0	0	110.6	V20 L21 A26 F27 C28 A54 L57 I58 A61	V20-I24 HydrophobicContact CG1-CD1 3.88Å; V20-I24 HydrophobicContact CG1-CG1 4.41Å; V20-I24 WeakPolarHBondContact O-CG1 3.1Å; V20-I24 PolarHBondContact O-N 3.46Å; L21-I24 PolarHBondContact O-N 3.18Å; I24-A26 PolarHBondContact O-N 3.5Å; I24-F27 PolarHBondContact O-N 2.86Å; I24-C28 PolarHBondContact O-N 2.9Å; I24-C28 PolarHBondContact O-SG 3.24Å; I24-A54 HydrophobicContact CG2-CB 4.37Å; I24-L57 HydrophobicContact CD1-CB 4.25Å; I24-L57 HydrophobicContact CG1-CB 4.28Å; I24-L57 HydrophobicContact CG2-CB 3.63Å; I24-L57 HydrophobicContact CG2-CD1 4.01Å; I24-L57 HydrophobicContact CG2-CG 4.49Å; I24-I58 HydrophobicContact CD1-CG1 4.27Å; I24-I58 HydrophobicContact CG2-CG1 4.33Å; I24-A61 HydrophobicContact CD1-CB 3.94Å
25	L	91.3	Very high	87.4	Confident	73 Å²	73	62.4 Å²	62.4	38%	0.382	32%	0.319	S	S	.	.	H	α-helix	trans	-62.7	-43.4	179	-71	176	0	0	0	112	L21 L22 C28 W29 A54	L21-L25 HydrophobicContact CD2-CD1 3.67Å; L21-L25 HydrophobicContact CD2-CG 4.35Å; L21-L25 WeakPolarHBondContact O-CG 3.42Å; L21-L25 PolarHBondContact O-N 3.19Å; L22-L25 PolarHBondContact O-N 2.96Å; L25-C28 PolarHBondContact O-N 3.29Å; L25-W29 VanDerWaalsContact O-CB 3.29Å; L25-W29 WeakPolarHBondContact O-CB 3.49Å; L25-W29 PolarHBondContact O-N 3.3Å; L25-A54 HydrophobicContact CD2-CB 3.93Å
26	A	92.4	Very high	87.8	Confident	48 Å²	48	61.2 Å²	61.2	40%	0.397	31%	0.307	S	S	.	.	H	α-helix	trans	-61.8	-43.8	175.6	0	0	0	0	0	111.5	L22 V23 I24 W29 I30	L22-A26 WeakPolarHBondContact O-CB 3.38Å; L22-A26 PolarHBondContact O-N 3.45Å; V23-A26 PolarHBondContact O-N 2.85Å; I24-A26 PolarHBondContact O-N 3.5Å; A26-W29 PolarHBondContact O-N 3.27Å; A26-I30 WeakPolarHBondContact O-CB 3.46Å; A26-I30 WeakPolarHBondContact O-CD1 3.31Å; A26-I30 VanDerWaalsContact O-CG1 3.22Å; A26-I30 WeakPolarHBondContact O-CG1 3.38Å; A26-I30 PolarHBondContact O-N 3.26Å
27	F	90.8	Very high	88.1	Confident	57 Å²	57	59.8 Å²	59.8	25%	0.25	30%	0.301	C	S	.	.	H	α-helix	trans	-60.1	-51.5	175.5	173.3	-97.1	0	0	0	111.6	V23 I24 W29 I30 Y31 L57 V378 L379 M382	V23-F27 VanDerWaalsContact O-CB 3.31Å; V23-F27 WeakPolarHBondContact O-CB 3.46Å; V23-F27 PolarHBondContact O-N 2.72Å; I24-F27 PolarHBondContact O-N 2.86Å; F27-W29 VanDerWaalsContact C-N 3.32Å; F27-W29 PolarHBondContact O-N 2.99Å; F27-I30 PolarHBondContact O-N 2.99Å; F27-Y31 WeakPolarHBondContact O-CB 3.3Å; F27-Y31 PolarHBondContact O-N 3.44Å; F27-L57 HydrophobicContact CD1-CD1 3.78Å; F27-L57 HydrophobicContact CE1-CD1 4.01Å; F27-V378 HydrophobicContact CE1-CG1 4.34Å; F27-V378 HydrophobicContact CZ-CG1 4.22Å; F27-L379 HydrophobicContact CE2-CD2 4.27Å; F27-L379 HydrophobicContact CZ-CD2 4.47Å; F27-M382 HydrophobicContact CZ-SD 4.31Å
28	C	91.9	Very high	88.1	Confident	0 Å²	0	64.8 Å²	64.8	0%	0	32%	0.318	C	S	.	.	H	α-helix	trans	-58.9	-43.8	178.5	-69.6	0	0	0	0	111.7	I24 L25 Y31 I32 I50 L53 A54	I24-C28 PolarHBondContact O-N 2.9Å; I24-C28 PolarHBondContact O-SG 3.24Å; L25-C28 PolarHBondContact O-N 3.29Å; C28-Y31 PolarHBondContact O-N 3.43Å; C28-I32 WeakPolarHBondContact O-CB 3.38Å; C28-I32 VanDerWaalsContact O-CG1 3.29Å; C28-I32 WeakPolarHBondContact O-CG1 3.43Å; C28-I32 PolarHBondContact O-N 2.95Å; C28-I50 HydrophobicContact CB-CG2 4.1Å; C28-L53 HydrophobicContact CB-CD2 4.46Å; C28-A54 PolarHBondContact SG-N 3.33Å
29	W	91.8	Very high	87.5	Confident	121 Å²	121	66.7 Å²	66.7	46%	0.458	32%	0.322	S	S	.	.	H	α-helix	trans	-61.2	-53.3	177.9	178.6	-92.5	0	0	0	112.4	L25 A26 F27 Y31 R33 I50	L25-W29 VanDerWaalsContact O-CB 3.29Å; L25-W29 WeakPolarHBondContact O-CB 3.49Å; L25-W29 PolarHBondContact O-N 3.3Å; A26-W29 PolarHBondContact O-N 3.27Å; F27-W29 VanDerWaalsContact C-N 3.32Å; F27-W29 PolarHBondContact O-N 2.99Å; W29-Y31 VanDerWaalsContact C-N 3.28Å; W29-Y31 PolarHBondContact O-N 3.17Å; W29-R33 VanDerWaalsContact CE2-NE 3.31Å; W29-R33 WeakPolarHBondContact O-CB 3.48Å; W29-R33 WeakPolarHBondContact O-CG 3.47Å; W29-R33 PolarHBondContact O-N 3.44Å; W29-I50 HydrophobicContact CE3-CD1 3.67Å; W29-I50 HydrophobicContact CZ3-CD1 4.13Å
30	I	91.3	Very high	86.9	Confident	114 Å²	114	65.8 Å²	65.8	59%	0.585	31%	0.314	S	S	*	.	H	α-helix	trans	-61.2	-42.8	179.4	-68.6	166.8	0	0	0	110	A26 F27 K34	A26-I30 WeakPolarHBondContact O-CB 3.46Å; A26-I30 WeakPolarHBondContact O-CD1 3.31Å; A26-I30 VanDerWaalsContact O-CG1 3.22Å; A26-I30 WeakPolarHBondContact O-CG1 3.38Å; A26-I30 PolarHBondContact O-N 3.26Å; F27-I30 PolarHBondContact O-N 2.99Å; I30-K34 WeakPolarHBondContact O-CB 3.44Å; I30-K34 PolarHBondContact O-N 2.74Å
31	Y	88.1	Confident	86.4	Confident	12 Å²	12	67.1 Å²	67.1	5%	0.047	32%	0.324	C	S	.	.	H	α-helix	trans	-61.9	-55.4	-179	176.3	-109.3	0	0	0	111.6	F27 C28 W29 R33 K34 F35 L53 M382 L413 L417	F27-Y31 WeakPolarHBondContact O-CB 3.3Å; F27-Y31 PolarHBondContact O-N 3.44Å; C28-Y31 PolarHBondContact O-N 3.43Å; W29-Y31 VanDerWaalsContact C-N 3.28Å; W29-Y31 PolarHBondContact O-N 3.17Å; Y31-R33 PolarHBondContact O-N 2.91Å; Y31-K34 WeakPolarHBondContact O-CB 3.35Å; Y31-K34 PolarHBondContact O-N 3.5Å; Y31-K34 VanDerWaalsContact O-N 3.14Å; Y31-F35 AromaticContact CD2-CD2 3.99Å; Y31-F35 HydrophobicContact CD2-CD2 3.99Å; Y31-F35 AromaticContact CD2-CE2 3.82Å; Y31-F35 HydrophobicContact CD2-CE2 3.82Å; Y31-F35 AromaticContact CE2-CD2 3.56Å; Y31-F35 HydrophobicContact CE2-CD2 3.56Å; Y31-F35 AromaticContact CE2-CE2 3.27Å; Y31-F35 HydrophobicContact CE2-CE2 3.27Å; Y31-F35 HydrophobicContact CE2-CZ 4.28Å; Y31-F35 WeakPolarHBondContact O-CD2 3.48Å; Y31-F35 PolarHBondContact O-N 3.4Å; Y31-L53 HydrophobicContact CD1-CD2 3.57Å; Y31-L53 HydrophobicContact CE1-CD2 4.02Å; Y31-M382 HydrophobicContact CD2-CE 3.52Å; Y31-M382 HydrophobicContact CD2-SD 3.85Å; Y31-M382 HydrophobicContact CE2-CE 3.15Å; Y31-M382 HydrophobicContact CE2-CG 4Å; Y31-M382 HydrophobicContact CE2-SD 3.37Å; Y31-M382 WeakPolarHBondContact CE2-SD 3.34Å; Y31-L413 HydrophobicContact CE1-CD2 4.45Å; Y31-L413 VanDerWaalsContact OH-CD2 3.23Å; Y31-L413 WeakPolarHBondContact OH-CD2 3.38Å; Y31-L417 HydrophobicContact CE1-CD1 3.65Å; Y31-L417 WeakPolarHBondContact OH-CD1 3.39Å
32	I	89.9	Confident	86.2	Confident	1 Å²	1	67.7 Å²	67.7	1%	0.005	33%	0.325	C	S	.	.	H	α-helix	trans	-63	-44.4	-177.3	-67.5	-59.6	0	0	0	110.9	C28 K34 F35 Q36 A49 I50 L410	C28-I32 WeakPolarHBondContact O-CB 3.38Å; C28-I32 VanDerWaalsContact O-CG1 3.29Å; C28-I32 WeakPolarHBondContact O-CG1 3.43Å; C28-I32 PolarHBondContact O-N 2.95Å; I32-K34 PolarHBondContact O-N 3.44Å; I32-F35 PolarHBondContact O-N 2.9Å; I32-F35 VanDerWaalsContact O-N 3.11Å; I32-Q36 WeakPolarHBondContact O-CB 3.19Å; I32-Q36 PolarHBondContact O-N 3.09Å; I32-A49 HydrophobicContact CD1-CB 3.73Å; I32-A49 HydrophobicContact CG1-CB 4.21Å; I32-A49 HydrophobicContact CG2-CB 4.36Å; I32-I50 HydrophobicContact CB-CD1 4.46Å; I32-I50 HydrophobicContact CB-CG1 3.79Å; I32-I50 HydrophobicContact CG1-CG1 3.79Å; I32-I50 HydrophobicContact CG2-CD1 4.38Å; I32-I50 HydrophobicContact CG2-CG1 3.99Å; I32-L410 HydrophobicContact CD1-CD1 3.9Å; I32-L410 HydrophobicContact CD1-CG 4.43Å; I32-L410 HydrophobicContact CG2-CD1 4.43Å; I32-L410 HydrophobicContact CG2-CD2 3.93Å
33	R	89.4	Confident	86	Confident	142 Å²	142	67.3 Å²	67.3	54%	0.536	33%	0.327	S	S	.	.	H	α-helix	trans	-63.4	-26.5	177.3	-75.6	-157.2	173.2	-154.8	-2.9	114	W29 Y31 F35	W29-R33 VanDerWaalsContact CE2-NE 3.31Å; W29-R33 WeakPolarHBondContact O-CB 3.48Å; W29-R33 WeakPolarHBondContact O-CG 3.47Å; W29-R33 PolarHBondContact O-N 3.44Å; Y31-R33 PolarHBondContact O-N 2.91Å; R33-F35 VanDerWaalsContact C-N 3.34Å
34	K	88.9	Confident	86	Confident	123 Å²	123	66.4 Å²	66.4	54%	0.535	32%	0.321	S	S	.	.	H	α-helix	trans	-69.4	-31.9	176.1	-178.1	176.6	179.1	175.6	0	112.5	I30 Y31 I32 K403	I30-K34 WeakPolarHBondContact O-CB 3.44Å; I30-K34 PolarHBondContact O-N 2.74Å; Y31-K34 WeakPolarHBondContact O-CB 3.35Å; Y31-K34 PolarHBondContact O-N 3.5Å; Y31-K34 VanDerWaalsContact O-N 3.14Å; I32-K34 PolarHBondContact O-N 3.44Å; K34-K403 PolarHBondContact O-N 2.87Å
35	F	85.6	Confident	85.9	Confident	13 Å²	13	65.7 Å²	65.7	6%	0.057	32%	0.318	C	S	.	.	H	α-helix	trans	-100.1	-26.8	-176.1	-74.6	-81.5	0	0	0	113.9	Y31 I32 R33 S37 I400 P402 T405 L410	Y31-F35 AromaticContact CD2-CD2 3.99Å; Y31-F35 HydrophobicContact CD2-CD2 3.99Å; Y31-F35 AromaticContact CD2-CE2 3.82Å; Y31-F35 HydrophobicContact CD2-CE2 3.82Å; Y31-F35 AromaticContact CE2-CD2 3.56Å; Y31-F35 HydrophobicContact CE2-CD2 3.56Å; Y31-F35 AromaticContact CE2-CE2 3.27Å; Y31-F35 HydrophobicContact CE2-CE2 3.27Å; Y31-F35 HydrophobicContact CE2-CZ 4.28Å; Y31-F35 WeakPolarHBondContact O-CD2 3.48Å; Y31-F35 PolarHBondContact O-N 3.4Å; I32-F35 PolarHBondContact O-N 2.9Å; I32-F35 VanDerWaalsContact O-N 3.11Å; R33-F35 VanDerWaalsContact C-N 3.34Å; F35-S37 PolarHBondContact O-N 3.1Å; F35-I400 HydrophobicContact CD1-CG2 3.5Å; F35-I400 HydrophobicContact CE1-CG2 3.76Å; F35-I400 HydrophobicContact CG-CG2 4.43Å; F35-P402 HydrophobicContact CE1-CG 4.23Å; F35-T405 WeakPolarHBondContact O-CB 3.39Å; F35-T405 PolarHBondContact O-N 3.23Å; F35-T405 VanDerWaalsContact O-N 3.13Å; F35-T405 PolarHBondContact O-OG1 3.46Å; F35-L410 HydrophobicContact CB-CD1 4.18Å
36	Q	86.8	Confident	85.8	Confident	33 Å²	33	62.9 Å²	62.9	15%	0.154	30%	0.304	C	S	.	.	B	Isolated β-bridge	trans	-50.5	130.4	175.9	176.9	179.8	-4.1	0	0	112.4	I32 S41 T46 K403 L410	I32-Q36 WeakPolarHBondContact O-CB 3.19Å; I32-Q36 PolarHBondContact O-N 3.09Å; Q36-S41 PolarHBondContact NE2-OG 2.86Å; Q36-T46 HydrophobicContact CG-CG2 3.94Å; Q36-T46 VanDerWaalsContact NE2-CG2 3.33Å; Q36-K403 CarbonylContact O-C 3.6Å; Q36-K403 WeakPolarHBondContact O-CA 3.36Å; Q36-L410 HydrophobicContact CB-CD2 4.49Å
37	S	82.9	Confident	85.8	Confident	9 Å²	9	64.8 Å²	64.8	6%	0.063	31%	0.307	C	S	.	.			trans	-59.5	140.5	170.7	-175.7	0	0	0	0	111.2	F35 Q39 S41 K403 T405	F35-S37 PolarHBondContact O-N 3.1Å; S37-Q39 PolarHBondContact OG-N 3.01Å; S37-S41 WeakPolarHBondContact O-CB 3.43Å; S37-K403 WeakPolarHBondContact CA-O 3.07Å; S37-T405 WeakPolarHBondContact CB-O 3.28Å; S37-T405 PolarHBondContact N-O 3.44Å
38	R	77.1	Confident	86	Confident	165 Å²	165	62.2 Å²	62.2	62%	0.623	30%	0.296	S	S	*	.	S	Bend	trans	-76.3	-28.7	173.2	-75.9	178.4	167.1	-177.8	-11.9	113.2	K403 E535	R38-K403 PolarHBondContact N-O 3.34Å; R38-E535 IonicContact NH1-OE1 3.52Å; R38-E535 PolarHBondContact NH1-OE1 2.72Å
39	Q	70.4	Confident	86	Confident	113 Å²	113	62.3 Å²	62.3	53%	0.528	30%	0.296	S	S	.	.	S	Bend	trans	-87.4	-47.6	-173.7	-69.1	170.3	-20.1	0	0	111.4	S37 S41	S37-Q39 PolarHBondContact OG-N 3.01Å; Q39-S41 PolarHBondContact O-N 3.36Å
40	D	74.3	Confident	86	Confident	68 Å²	68	57.5 Å²	57.5	36%	0.364	28%	0.279	S	S	.	.	S	Bend	trans	-103	29.1	-170.7	-58	-30.7	0	0	0	113.4	P407	D40-P407 WeakPolarHBondContact O-CD 3.4Å; D40-P407 WeakPolarHBondContact O-CG 3.45Å
41	S	74.8	Confident	86.1	Confident	50 Å²	50	55 Å²	55	35%	0.35	27%	0.271	S	S	.	.			trans	-85.6	119.8	-165.4	119.8	0	0	0	0	112.3	Q36 S37 Q39	Q36-S41 PolarHBondContact NE2-OG 2.86Å; S37-S41 WeakPolarHBondContact O-CB 3.43Å; Q39-S41 PolarHBondContact O-N 3.36Å
42	E	81.9	Confident	86.3	Confident	67 Å²	67	54.5 Å²	54.5	31%	0.313	27%	0.27	S	S	.	.			trans	-109.4	140.1	177.1	-76.4	-67.9	174.7	0	0	113.3	S45 T46 Y123 K126	E42-S45 WeakPolarHBondContact CB-OG 3.43Å; E42-S45 PolarHBondContact O-OG 3.22Å; E42-T46 WeakPolarHBondContact O-CG2 3.4Å; E42-T46 PolarHBondContact O-N 3.47Å; E42-T46 PolarHBondContact O-OG1 3.4Å; E42-Y123 HydrophobicContact CB-CD2 4.48Å; E42-Y123 HydrophobicContact CB-CE2 4.42Å; E42-Y123 HydrophobicContact CG-CD2 4.02Å; E42-Y123 HydrophobicContact CG-CE2 3.74Å; E42-K126 IonicContact OE1-NZ 3.93Å; E42-K126 PolarHBondContact OE1-NZ 2.54Å
43	V	86.6	Confident	86.4	Confident	96 Å²	96	54.5 Å²	54.5	58%	0.582	27%	0.27	S	S	*	.	H	α-helix	trans	-67.2	-40.4	-175.6	180	0	0	0	0	111.4	T46 I47	V43-T46 WeakPolarHBondContact CA-OG1 3.41Å; V43-T46 PolarHBondContact O-N 3.36Å; V43-T46 PolarHBondContact O-OG1 3.04Å; V43-I47 HydrophobicContact CG1-CD1 3.59Å; V43-I47 HydrophobicContact CG1-CG1 4.23Å; V43-I47 WeakPolarHBondContact O-CB 3.31Å; V43-I47 VanDerWaalsContact O-CG1 3.29Å; V43-I47 WeakPolarHBondContact O-CG1 3.24Å; V43-I47 PolarHBondContact O-N 3.16Å
44	V	89.3	Confident	86.6	Confident	71 Å²	71	48 Å²	48	43%	0.43	25%	0.246	S	C	.	.	H	α-helix	trans	-66.4	-44.2	-177.3	-179.2	0	0	0	0	111.6	T46 T48 V119	V44-T46 VanDerWaalsContact C-N 3.32Å; V44-T46 PolarHBondContact O-N 3.22Å; V44-T48 VanDerWaalsContact O-CB 3.26Å; V44-T48 WeakPolarHBondContact O-CB 3.27Å; V44-T48 PolarHBondContact O-N 3.44Å; V44-T48 PolarHBondContact O-OG1 3.07Å; V44-V119 HydrophobicContact CG1-CG1 4.16Å; V44-V119 HydrophobicContact CG1-CG2 4.22Å
45	S	88.7	Confident	86.9	Confident	3 Å²	3	43.6 Å²	43.6	2%	0.021	23%	0.228	C	C	.	.	H	α-helix	trans	-65.2	-36.4	178	49.8	0	0	0	0	112.7	E42 T48 A49	E42-S45 WeakPolarHBondContact CB-OG 3.43Å; E42-S45 PolarHBondContact O-OG 3.22Å; S45-T48 PolarHBondContact O-N 3Å; S45-A49 WeakPolarHBondContact O-CB 3.29Å; S45-A49 PolarHBondContact O-N 2.92Å
46	T	90.1	Very high	87.2	Confident	14 Å²	14	43 Å²	43	9%	0.086	23%	0.226	C	C	.	.	H	α-helix	trans	-75.4	-44	-176.5	50.9	0	0	0	0	111.1	Q36 E42 V43 V44 T48 A49 I50 L410	Q36-T46 HydrophobicContact CG-CG2 3.94Å; Q36-T46 VanDerWaalsContact NE2-CG2 3.33Å; E42-T46 WeakPolarHBondContact O-CG2 3.4Å; E42-T46 PolarHBondContact O-N 3.47Å; E42-T46 PolarHBondContact O-OG1 3.4Å; V43-T46 WeakPolarHBondContact CA-OG1 3.41Å; V43-T46 PolarHBondContact O-N 3.36Å; V43-T46 PolarHBondContact O-OG1 3.04Å; V44-T46 VanDerWaalsContact C-N 3.32Å; V44-T46 PolarHBondContact O-N 3.22Å; T46-T48 VanDerWaalsContact C-N 3.3Å; T46-T48 PolarHBondContact O-N 3.17Å; T46-A49 PolarHBondContact O-N 3.38Å; T46-I50 WeakPolarHBondContact O-CD1 3.35Å; T46-I50 VanDerWaalsContact O-CG1 3.22Å; T46-I50 WeakPolarHBondContact O-CG1 3.45Å; T46-I50 PolarHBondContact O-N 2.98Å; T46-L410 HydrophobicContact CG2-CD2 4.36Å
47	I	92.3	Very high	87.5	Confident	89 Å²	89	42 Å²	42	46%	0.456	22%	0.222	S	C	.	.	H	α-helix	trans	-58.6	-45.2	171.1	-67.1	173	0	0	0	110.1	V43 A49 I50 C51	V43-I47 HydrophobicContact CG1-CD1 3.59Å; V43-I47 HydrophobicContact CG1-CG1 4.23Å; V43-I47 WeakPolarHBondContact O-CB 3.31Å; V43-I47 VanDerWaalsContact O-CG1 3.29Å; V43-I47 WeakPolarHBondContact O-CG1 3.24Å; V43-I47 PolarHBondContact O-N 3.16Å; I47-A49 PolarHBondContact O-N 3.11Å; I47-I50 PolarHBondContact O-N 3.45Å; I47-C51 WeakPolarHBondContact O-CB 3.46Å; I47-C51 PolarHBondContact O-N 2.59Å; I47-C51 PolarHBondContact O-SG 3.38Å
48	T	93.3	Very high	87.9	Confident	3 Å²	3	43.1 Å²	43.1	2%	0.018	23%	0.226	C	C	.	.	H	α-helix	trans	-58.9	-46.4	178.5	-63.4	0	0	0	0	112.2	V44 S45 T46 C51 A52 W115 I116 V119 L411	V44-T48 VanDerWaalsContact O-CB 3.26Å; V44-T48 WeakPolarHBondContact O-CB 3.27Å; V44-T48 PolarHBondContact O-N 3.44Å; V44-T48 PolarHBondContact O-OG1 3.07Å; S45-T48 PolarHBondContact O-N 3Å; T46-T48 VanDerWaalsContact C-N 3.3Å; T46-T48 PolarHBondContact O-N 3.17Å; T48-C51 PolarHBondContact O-N 3.14Å; T48-A52 VanDerWaalsContact O-CB 3.28Å; T48-A52 WeakPolarHBondContact O-CB 3.11Å; T48-A52 PolarHBondContact O-N 3.31Å; T48-W115 PolarHBondContact OG1-NE1 3.37Å; T48-I116 HydrophobicContact CG2-CG1 4.21Å; T48-V119 HydrophobicContact CG2-CB 4.49Å; T48-V119 HydrophobicContact CG2-CG2 4.29Å; T48-L411 HydrophobicContact CG2-CD2 3.77Å
49	A	92.1	Very high	88.6	Confident	1 Å²	1	35.4 Å²	35.4	1%	0.008	20%	0.198	C	C	.	.	H	α-helix	trans	-64.9	-40.3	177.5	0	0	0	0	0	112.3	I32 S45 T46 I47 L53 L410 L411 C414	I32-A49 HydrophobicContact CD1-CB 3.73Å; I32-A49 HydrophobicContact CG1-CB 4.21Å; I32-A49 HydrophobicContact CG2-CB 4.36Å; S45-A49 WeakPolarHBondContact O-CB 3.29Å; S45-A49 PolarHBondContact O-N 2.92Å; T46-A49 PolarHBondContact O-N 3.38Å; I47-A49 PolarHBondContact O-N 3.11Å; A49-L53 WeakPolarHBondContact O-CB 3.38Å; A49-L53 PolarHBondContact O-N 3.23Å; A49-L53 VanDerWaalsContact O-N 3.11Å; A49-L410 HydrophobicContact CB-CD2 4.5Å; A49-L410 HydrophobicContact CB-CG 4.35Å; A49-L411 HydrophobicContact CB-CD2 4.47Å; A49-C414 HydrophobicContact CB-CB 4.13Å; A49-C414 PolarHBondContact O-SG 3.49Å
50	I	92.8	Very high	89.5	Confident	21 Å²	21	30.1 Å²	30.1	11%	0.108	17%	0.173	C	C	.	.	H	α-helix	trans	-63.7	-48.8	176.6	-68	161.7	0	0	0	110.3	C28 W29 I32 T46 I47 A54	C28-I50 HydrophobicContact CB-CG2 4.1Å; W29-I50 HydrophobicContact CE3-CD1 3.67Å; W29-I50 HydrophobicContact CZ3-CD1 4.13Å; I32-I50 HydrophobicContact CB-CD1 4.46Å; I32-I50 HydrophobicContact CB-CG1 3.79Å; I32-I50 HydrophobicContact CG1-CG1 3.79Å; I32-I50 HydrophobicContact CG2-CD1 4.38Å; I32-I50 HydrophobicContact CG2-CG1 3.99Å; T46-I50 WeakPolarHBondContact O-CD1 3.35Å; T46-I50 VanDerWaalsContact O-CG1 3.22Å; T46-I50 WeakPolarHBondContact O-CG1 3.45Å; T46-I50 PolarHBondContact O-N 2.98Å; I47-I50 PolarHBondContact O-N 3.45Å; I50-A54 WeakPolarHBondContact O-CB 3.17Å; I50-A54 PolarHBondContact O-N 3.47Å
51	C	93.4	Very high	90.2	Very high	61 Å²	61	27.2 Å²	27.2	41%	0.412	16%	0.159	S	C	.	.	H	α-helix	trans	-63.3	-48.5	-179.4	-70.8	0	0	0	0	111.6	I47 T48 L53 A54 I55	I47-C51 WeakPolarHBondContact O-CB 3.46Å; I47-C51 PolarHBondContact O-N 2.59Å; I47-C51 PolarHBondContact O-SG 3.38Å; T48-C51 PolarHBondContact O-N 3.14Å; C51-L53 PolarHBondContact O-N 3.09Å; C51-A54 PolarHBondContact O-N 2.91Å; C51-I55 WeakPolarHBondContact O-CB 3.14Å; C51-I55 WeakPolarHBondContact O-CD1 3.3Å; C51-I55 VanDerWaalsContact O-CG1 3.25Å; C51-I55 WeakPolarHBondContact O-CG1 3.46Å; C51-I55 PolarHBondContact O-N 3.48Å
52	A	92.9	Very high	90.8	Very high	2 Å²	2	25.9 Å²	25.9	2%	0.017	15%	0.148	C	C	.	.	H	α-helix	trans	-61.5	-44.3	-179.2	0	0	0	0	0	112.1	T48 A56 I116 L418	T48-A52 VanDerWaalsContact O-CB 3.28Å; T48-A52 WeakPolarHBondContact O-CB 3.11Å; T48-A52 PolarHBondContact O-N 3.31Å; A52-A56 PolarHBondContact O-N 3.37Å; A52-A56 VanDerWaalsContact O-N 3.17Å; A52-I116 HydrophobicContact CB-CD1 3.96Å; A52-L418 HydrophobicContact CB-CD1 4.38Å
53	L	91.8	Very high	91.1	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-66.8	-40.3	176.1	-172.6	62.1	0	0	0	111.9	C28 Y31 A49 C51 A56 L57 L417	C28-L53 HydrophobicContact CB-CD2 4.46Å; Y31-L53 HydrophobicContact CD1-CD2 3.57Å; Y31-L53 HydrophobicContact CE1-CD2 4.02Å; A49-L53 WeakPolarHBondContact O-CB 3.38Å; A49-L53 PolarHBondContact O-N 3.23Å; A49-L53 VanDerWaalsContact O-N 3.11Å; C51-L53 PolarHBondContact O-N 3.09Å; L53-A56 PolarHBondContact O-N 2.84Å; L53-L57 HydrophobicContact CG-CD1 4.27Å; L53-L57 WeakPolarHBondContact O-CG 3.39Å; L53-L57 PolarHBondContact O-N 3.11Å; L53-L417 HydrophobicContact CD1-CB 3.94Å; L53-L417 HydrophobicContact CD1-CD1 4.44Å
54	A	93.9	Very high	91.1	Very high	5 Å²	5	18.2 Å²	18.2	4%	0.041	11%	0.106	C	C	.	.	H	α-helix	trans	-62.7	-45	177.6	0	0	0	0	0	111.7	I24 L25 C28 I50 C51 A56 L57 I58	I24-A54 HydrophobicContact CG2-CB 4.37Å; L25-A54 HydrophobicContact CD2-CB 3.93Å; C28-A54 PolarHBondContact SG-N 3.33Å; I50-A54 WeakPolarHBondContact O-CB 3.17Å; I50-A54 PolarHBondContact O-N 3.47Å; C51-A54 PolarHBondContact O-N 2.91Å; A54-A56 VanDerWaalsContact C-N 3.31Å; A54-A56 PolarHBondContact O-N 3.38Å; A54-L57 PolarHBondContact O-N 3Å; A54-I58 WeakPolarHBondContact O-CB 3.24Å; A54-I58 WeakPolarHBondContact O-CD1 3.44Å; A54-I58 WeakPolarHBondContact O-CG1 3.4Å; A54-I58 PolarHBondContact O-N 3.15Å
55	I	93.7	Very high	91	Very high	31 Å²	31	16.6 Å²	16.6	16%	0.159	10%	0.096	C	C	.	.	H	α-helix	trans	-60.1	-43.2	177.4	-69.3	155.3	0	0	0	110.5	C51 I58 T59 I107 I108	C51-I55 WeakPolarHBondContact O-CB 3.14Å; C51-I55 WeakPolarHBondContact O-CD1 3.3Å; C51-I55 VanDerWaalsContact O-CG1 3.25Å; C51-I55 WeakPolarHBondContact O-CG1 3.46Å; C51-I55 PolarHBondContact O-N 3.48Å; I55-I58 PolarHBondContact O-N 2.85Å; I55-T59 WeakPolarHBondContact O-CB 3.18Å; I55-T59 PolarHBondContact O-N 2.96Å; I55-T59 PolarHBondContact O-OG1 2.65Å; I55-I107 HydrophobicContact CD1-CG2 3.46Å; I55-I107 VanDerWaalsContact CD1-CG2 3.46Å; I55-I107 HydrophobicContact CG1-CG2 4.16Å; I55-I107 HydrophobicContact CG2-CB 4.43Å; I55-I107 HydrophobicContact CG2-CG2 3.99Å; I55-I108 HydrophobicContact CG2-CD1 4.4Å; I55-I108 HydrophobicContact CG2-CG1 3.76Å
56	A	92.4	Very high	91	Very high	2 Å²	2	16.5 Å²	16.5	2%	0.017	10%	0.095	C	C	.	.	H	α-helix	trans	-60.3	-47.7	177	0	0	0	0	0	111.8	A52 L53 A54 T59 S60 L418 V421	A52-A56 PolarHBondContact O-N 3.37Å; A52-A56 VanDerWaalsContact O-N 3.17Å; L53-A56 PolarHBondContact O-N 2.84Å; A54-A56 VanDerWaalsContact C-N 3.31Å; A54-A56 PolarHBondContact O-N 3.38Å; A56-T59 WeakPolarHBondContact O-CB 3.44Å; A56-T59 PolarHBondContact O-N 3Å; A56-S60 PolarHBondContact O-N 3.48Å; A56-L418 HydrophobicContact CB-CB 4.08Å; A56-L418 HydrophobicContact CB-CD1 4.45Å; A56-L418 HydrophobicContact CB-CG 3.88Å; A56-V421 HydrophobicContact CB-CB 4.18Å; A56-V421 HydrophobicContact CB-CG1 4.12Å; A56-V421 VanDerWaalsContact O-CG1 3.3Å; A56-V421 WeakPolarHBondContact O-CG1 3.31Å
57	L	91.9	Very high	90.9	Very high	12 Å²	12	15.8 Å²	15.8	6%	0.063	9%	0.091	C	C	.	.	H	α-helix	trans	-68	-38.3	179.4	-69.4	176	0	0	0	112.7	I24 F27 L53 A54 T59 S60 A61 V378 V421	I24-L57 HydrophobicContact CD1-CB 4.25Å; I24-L57 HydrophobicContact CG1-CB 4.28Å; I24-L57 HydrophobicContact CG2-CB 3.63Å; I24-L57 HydrophobicContact CG2-CD1 4.01Å; I24-L57 HydrophobicContact CG2-CG 4.49Å; F27-L57 HydrophobicContact CD1-CD1 3.78Å; F27-L57 HydrophobicContact CE1-CD1 4.01Å; L53-L57 HydrophobicContact CG-CD1 4.27Å; L53-L57 WeakPolarHBondContact O-CG 3.39Å; L53-L57 PolarHBondContact O-N 3.11Å; A54-L57 PolarHBondContact O-N 3Å; L57-T59 VanDerWaalsContact C-N 3.29Å; L57-T59 PolarHBondContact O-N 3.37Å; L57-S60 PolarHBondContact O-N 3.01Å; L57-A61 WeakPolarHBondContact O-CB 3.41Å; L57-A61 PolarHBondContact O-N 3.12Å; L57-V378 HydrophobicContact CD2-CG2 4.1Å; L57-V421 HydrophobicContact CD2-CG1 4.42Å; L57-V421 HydrophobicContact CD2-CG2 3.97Å
58	I	92	Very high	90.5	Very high	31 Å²	31	14 Å²	14	16%	0.159	8%	0.08	C	C	.	.	H	α-helix	trans	-61.4	-41.4	173.5	-71.1	164.9	0	0	0	110.1	L21 I24 A54 I55 S60 A61 L62 L104	L21-I58 HydrophobicContact CD1-CD1 4.25Å; L21-I58 HydrophobicContact CG-CD1 4.46Å; I24-I58 HydrophobicContact CD1-CG1 4.27Å; I24-I58 HydrophobicContact CG2-CG1 4.33Å; A54-I58 WeakPolarHBondContact O-CB 3.24Å; A54-I58 WeakPolarHBondContact O-CD1 3.44Å; A54-I58 WeakPolarHBondContact O-CG1 3.4Å; A54-I58 PolarHBondContact O-N 3.15Å; I55-I58 PolarHBondContact O-N 2.85Å; I58-S60 VanDerWaalsContact C-N 3.33Å; I58-S60 PolarHBondContact O-N 3.24Å; I58-A61 CarbonylContact O-C 3.57Å; I58-A61 PolarHBondContact O-N 2.92Å; I58-A61 VanDerWaalsContact O-N 3.13Å; I58-L62 PolarHBondContact O-N 3.24Å; I58-L104 HydrophobicContact CG2-CD1 4.17Å; I58-L104 HydrophobicContact CG2-CD2 4.07Å
59	T	91.5	Very high	90.1	Very high	3 Å²	3	16.1 Å²	16.1	2%	0.018	9%	0.091	C	C	.	.	H	α-helix	trans	-61.8	-41.8	176.3	-51.9	0	0	0	0	111.5	I55 A56 L57 A61 L62 L104 Y105 I108	I55-T59 WeakPolarHBondContact O-CB 3.18Å; I55-T59 PolarHBondContact O-N 2.96Å; I55-T59 PolarHBondContact O-OG1 2.65Å; A56-T59 WeakPolarHBondContact O-CB 3.44Å; A56-T59 PolarHBondContact O-N 3Å; L57-T59 VanDerWaalsContact C-N 3.29Å; L57-T59 PolarHBondContact O-N 3.37Å; T59-A61 VanDerWaalsContact C-N 3.34Å; T59-L62 WeakPolarHBondContact O-CB 3.42Å; T59-L62 PolarHBondContact O-N 2.98Å; T59-L104 HydrophobicContact CG2-CB 4.29Å; T59-Y105 HydrophobicContact CG2-CD1 3.9Å; T59-Y105 HydrophobicContact CG2-CE1 3.4Å; T59-I108 HydrophobicContact CG2-CD1 4.06Å; T59-I108 WeakPolarHBondContact OG1-CD1 3.18Å
60	S	90.2	Very high	89.8	Confident	2 Å²	2	16.3 Å²	16.3	1%	0.014	9%	0.092	C	C	.	.	H	α-helix	trans	-69.5	-31.2	173.9	-164.4	0	0	0	0	112.9	A56 L57 I58 L62 L63 P64 T374	A56-S60 PolarHBondContact O-N 3.48Å; L57-S60 PolarHBondContact O-N 3.01Å; I58-S60 VanDerWaalsContact C-N 3.33Å; I58-S60 PolarHBondContact O-N 3.24Å; S60-L62 PolarHBondContact O-N 3.34Å; S60-L63 WeakPolarHBondContact O-CB 3.43Å; S60-L63 PolarHBondContact O-N 3.43Å; S60-P64 WeakPolarHBondContact O-CD 3.4Å; S60-T374 WeakPolarHBondContact OG-CG2 3.47Å
61	A	88.4	Confident	89.5	Confident	8 Å²	8	15.8 Å²	15.8	7%	0.066	9%	0.09	C	C	.	.	H	α-helix	trans	-73.5	-15.2	176.2	0	0	0	0	0	113.2	V20 I24 L57 I58 T59 P64	V20-A61 HydrophobicContact CG1-CB 4.29Å; I24-A61 HydrophobicContact CD1-CB 3.94Å; L57-A61 WeakPolarHBondContact O-CB 3.41Å; L57-A61 PolarHBondContact O-N 3.12Å; I58-A61 CarbonylContact O-C 3.57Å; I58-A61 PolarHBondContact O-N 2.92Å; I58-A61 VanDerWaalsContact O-N 3.13Å; T59-A61 VanDerWaalsContact C-N 3.34Å; A61-P64 WeakPolarHBondContact O-CD 3.34Å; A61-P64 WeakPolarHBondContact O-CG 3.39Å
62	L	88.6	Confident	89.1	Confident	22 Å²	22	16.1 Å²	16.1	12%	0.115	8%	0.083	C	C	.	.	H	α-helix	trans	-73	-28.2	171.2	-169.5	60.9	0	0	0	111.8	I58 T59 S60 V65 D66 Y101 L104	I58-L62 PolarHBondContact O-N 3.24Å; T59-L62 WeakPolarHBondContact O-CB 3.42Å; T59-L62 PolarHBondContact O-N 2.98Å; S60-L62 PolarHBondContact O-N 3.34Å; L62-V65 HydrophobicContact CD1-CB 4.29Å; L62-V65 WeakPolarHBondContact O-CA 3.31Å; L62-V65 WeakPolarHBondContact O-CB 3.41Å; L62-V65 PolarHBondContact O-N 2.96Å; L62-D66 PolarHBondContact O-N 3.43Å; L62-Y101 HydrophobicContact CB-CE1 4.1Å; L62-Y101 HydrophobicContact CD2-CD1 3.81Å; L62-Y101 HydrophobicContact CD2-CD2 3.82Å; L62-Y101 HydrophobicContact CD2-CE1 3.69Å; L62-Y101 HydrophobicContact CD2-CE2 3.68Å; L62-Y101 HydrophobicContact CD2-CG 3.85Å; L62-Y101 HydrophobicContact CG-CD2 4.47Å; L62-Y101 HydrophobicContact CG-CE1 4.02Å; L62-Y101 HydrophobicContact CG-CE2 3.84Å; L62-Y101 PolarHBondContact O-OH 2.9Å; L62-L104 HydrophobicContact CD2-CD1 3.9Å
63	L	88.3	Confident	88.7	Confident	1 Å²	1	16.1 Å²	16.1	1%	0.005	8%	0.083	C	C	.	.	H	α-helix	trans	-54.4	-53.7	179.3	178	69.4	0	0	0	113.6	S60 V65 D66 I67 Y101 I428 V436 T479	S60-L63 WeakPolarHBondContact O-CB 3.43Å; S60-L63 PolarHBondContact O-N 3.43Å; L63-V65 PolarHBondContact O-N 3.48Å; L63-D66 WeakPolarHBondContact O-CB 3.21Å; L63-D66 PolarHBondContact O-N 3.4Å; L63-I67 HydrophobicContact CD1-CD1 4.17Å; L63-I67 HydrophobicContact CG-CD1 4.06Å; L63-I67 WeakPolarHBondContact O-CG1 3.4Å; L63-I67 PolarHBondContact O-N 3.42Å; L63-Y101 VanDerWaalsContact CA-OH 3.22Å; L63-Y101 WeakPolarHBondContact CA-OH 3.45Å; L63-Y101 PolarHBondContact N-OH 3.48Å; L63-Y101 VanDerWaalsContact N-OH 3.08Å; L63-I428 HydrophobicContact CD2-CB 4.13Å; L63-I428 HydrophobicContact CD2-CD1 3.82Å; L63-I428 HydrophobicContact CD2-CG2 3.86Å; L63-V436 HydrophobicContact CD1-CG1 4.24Å; L63-T479 HydrophobicContact CD1-CG2 3.89Å
64	P	86.7	Confident	88.5	Confident	1 Å²	1	16.7 Å²	16.7	1%	0.006	9%	0.085	C	C	.	.	H	α-helix	trans	-66.2	-24	177.2	26.9	-36.2	0	0	0	113	S60 A61 F68 Y367 I370	S60-P64 WeakPolarHBondContact O-CD 3.4Å; A61-P64 WeakPolarHBondContact O-CD 3.34Å; A61-P64 WeakPolarHBondContact O-CG 3.39Å; P64-F68 WeakPolarHBondContact O-CB 3.46Å; P64-F68 PolarHBondContact O-N 3.18Å; P64-Y367 HydrophobicContact CB-CD2 3.56Å; P64-Y367 HydrophobicContact CB-CE2 3.99Å; P64-Y367 HydrophobicContact CB-CG 4.14Å; P64-Y367 HydrophobicContact CG-CD2 3.63Å; P64-Y367 HydrophobicContact CG-CE2 3.53Å; P64-Y367 HydrophobicContact CG-CG 4.27Å; P64-I370 HydrophobicContact CB-CB 4.35Å; P64-I370 HydrophobicContact CB-CG2 4.26Å; P64-I370 HydrophobicContact CG-CG2 4.18Å
65	V	85.5	Confident	88.1	Confident	36 Å²	36	21.4 Å²	21.4	22%	0.218	10%	0.103	C	C	.	.	H	α-helix	trans	-70.2	-43.8	173.2	-178.6	0	0	0	0	110.9	F17 L62 L63 F68 L69 Y367	F17-V65 HydrophobicContact CD2-CG2 4.38Å; L62-V65 HydrophobicContact CD1-CB 4.29Å; L62-V65 WeakPolarHBondContact O-CA 3.31Å; L62-V65 WeakPolarHBondContact O-CB 3.41Å; L62-V65 PolarHBondContact O-N 2.96Å; L63-V65 PolarHBondContact O-N 3.48Å; V65-F68 PolarHBondContact O-N 3.41Å; V65-L69 HydrophobicContact CG1-CD1 3.9Å; V65-L69 HydrophobicContact CG1-CG 4.31Å; V65-L69 WeakPolarHBondContact O-CB 3.31Å; V65-L69 VanDerWaalsContact O-CG 3.29Å; V65-L69 WeakPolarHBondContact O-CG 3.26Å; V65-L69 PolarHBondContact O-N 2.88Å; V65-Y367 HydrophobicContact CG2-CE2 3.83Å
66	D	89.3	Confident	87.7	Confident	1 Å²	1	24.6 Å²	24.6	1%	0.005	13%	0.126	C	C	.	.	H	α-helix	trans	-57.9	-51.2	174.9	-172.6	11	0	0	0	110.4	L62 L63 F68 L69 V70 V97 Y101 T477 R478 T479	L62-D66 PolarHBondContact O-N 3.43Å; L63-D66 WeakPolarHBondContact O-CB 3.21Å; L63-D66 PolarHBondContact O-N 3.4Å; D66-F68 PolarHBondContact O-N 3.16Å; D66-L69 PolarHBondContact O-N 3.44Å; D66-V70 VanDerWaalsContact O-CG2 3.31Å; D66-V70 WeakPolarHBondContact O-CG2 3.46Å; D66-V70 PolarHBondContact O-N 3.24Å; D66-V70 VanDerWaalsContact O-N 3.14Å; D66-V97 HydrophobicContact CB-CG1 4.04Å; D66-Y101 HydrophobicContact CB-CE2 4.13Å; D66-T477 WeakPolarHBondContact OD2-CB 3.39Å; D66-R478 PolarHBondContact OD1-N 2.91Å; D66-R478 PolarHBondContact OD2-N 3.38Å; D66-T479 PolarHBondContact OD2-N 2.81Å; D66-T479 PolarHBondContact OD2-OG1 3.26Å
67	I	87.1	Confident	87.3	Confident	0 Å²	0	29.8 Å²	29.8	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-59.3	-45.5	177	-63	165.1	0	0	0	111.3	L63 S71 Y435 V436 T477	L63-I67 HydrophobicContact CD1-CD1 4.17Å; L63-I67 HydrophobicContact CG-CD1 4.06Å; L63-I67 WeakPolarHBondContact O-CG1 3.4Å; L63-I67 PolarHBondContact O-N 3.42Å; I67-S71 WeakPolarHBondContact O-CB 3.17Å; I67-S71 PolarHBondContact O-N 3.46Å; I67-S71 PolarHBondContact O-OG 3.28Å; I67-Y435 HydrophobicContact CD1-CD1 4.16Å; I67-Y435 HydrophobicContact CD1-CE1 3.61Å; I67-Y435 HydrophobicContact CG2-CE1 4.25Å; I67-Y435 HydrophobicContact CG2-CE2 4.04Å; I67-V436 HydrophobicContact CD1-CB 4.45Å; I67-V436 HydrophobicContact CD1-CG1 4.47Å; I67-V436 HydrophobicContact CD1-CG2 4.22Å; I67-T477 HydrophobicContact CB-CG2 4.48Å; I67-T477 HydrophobicContact CG1-CG2 3.95Å
68	F	85.3	Confident	86.9	Confident	52 Å²	52	29.4 Å²	29.4	23%	0.228	15%	0.152	C	C	.	.	H	α-helix	trans	-62.1	-46.5	179.1	172	-99.7	0	0	0	112.2	P64 V65 D66 V70 S71 Y72 F363	P64-F68 WeakPolarHBondContact O-CB 3.46Å; P64-F68 PolarHBondContact O-N 3.18Å; V65-F68 PolarHBondContact O-N 3.41Å; D66-F68 PolarHBondContact O-N 3.16Å; F68-V70 VanDerWaalsContact C-N 3.33Å; F68-V70 PolarHBondContact O-N 3.21Å; F68-S71 PolarHBondContact O-N 3.17Å; F68-Y72 HydrophobicContact CE1-CG 4.31Å; F68-Y72 HydrophobicContact CE2-CD2 4.1Å; F68-Y72 HydrophobicContact CE2-CG 4.46Å; F68-Y72 AromaticContact CZ-CD2 3.74Å; F68-Y72 HydrophobicContact CZ-CD2 3.74Å; F68-Y72 HydrophobicContact CZ-CE2 4.42Å; F68-Y72 AromaticContact CZ-CG 3.94Å; F68-Y72 HydrophobicContact CZ-CG 3.94Å; F68-Y72 WeakPolarHBondContact O-CB 3.34Å; F68-Y72 PolarHBondContact O-N 2.95Å; F68-F363 HydrophobicContact CD1-CE2 4.49Å; F68-F363 AromaticContact CD2-CD2 3.57Å; F68-F363 HydrophobicContact CD2-CD2 3.57Å; F68-F363 AromaticContact CD2-CE2 3.68Å; F68-F363 HydrophobicContact CD2-CE2 3.68Å; F68-F363 HydrophobicContact CE1-CE2 4.43Å; F68-F363 AromaticContact CE2-CD2 3.35Å; F68-F363 HydrophobicContact CE2-CD2 3.35Å; F68-F363 AromaticContact CE2-CE2 3.61Å; F68-F363 HydrophobicContact CE2-CE2 3.61Å; F68-F363 HydrophobicContact CE2-CG 4.05Å; F68-F363 HydrophobicContact CE2-CZ 4.47Å; F68-F363 HydrophobicContact CG-CD2 4.45Å; F68-F363 HydrophobicContact CG-CE2 4.13Å; F68-F363 HydrophobicContact CZ-CD2 4.1Å; F68-F363 HydrophobicContact CZ-CE2 4.01Å; F68-F363 HydrophobicContact CZ-CZ 4.48Å
69	L	84.5	Confident	86.7	Confident	47 Å²	47	31 Å²	31	25%	0.246	16%	0.163	C	C	.	.	H	α-helix	trans	-61.1	-44.6	-177.6	-77	170	0	0	0	111.3	V65 D66 Y72 M73 I93 V97	V65-L69 HydrophobicContact CG1-CD1 3.9Å; V65-L69 HydrophobicContact CG1-CG 4.31Å; V65-L69 WeakPolarHBondContact O-CB 3.31Å; V65-L69 VanDerWaalsContact O-CG 3.29Å; V65-L69 WeakPolarHBondContact O-CG 3.26Å; V65-L69 PolarHBondContact O-N 2.88Å; D66-L69 PolarHBondContact O-N 3.44Å; L69-Y72 PolarHBondContact O-N 3.3Å; L69-M73 WeakPolarHBondContact O-CG 3.37Å; L69-M73 PolarHBondContact O-N 2.89Å; L69-I93 HydrophobicContact CD1-CG2 4.4Å; L69-I93 HydrophobicContact CD2-CG2 4.3Å; L69-V97 HydrophobicContact CD1-CG2 3.34Å
70	V	86.1	Confident	86.5	Confident	4 Å²	4	33.1 Å²	33.1	2%	0.024	17%	0.171	C	C	.	.	H	α-helix	trans	-67.2	-41.9	179.2	176.3	0	0	0	0	110.8	D66 F68 Y72 T475 T477	D66-V70 VanDerWaalsContact O-CG2 3.31Å; D66-V70 WeakPolarHBondContact O-CG2 3.46Å; D66-V70 PolarHBondContact O-N 3.24Å; D66-V70 VanDerWaalsContact O-N 3.14Å; F68-V70 VanDerWaalsContact C-N 3.33Å; F68-V70 PolarHBondContact O-N 3.21Å; V70-Y72 PolarHBondContact O-N 2.87Å; V70-T475 WeakPolarHBondContact CG1-O 3.44Å; V70-T475 WeakPolarHBondContact CG1-OG1 3.38Å; V70-T477 HydrophobicContact CB-CG2 4.38Å; V70-T477 HydrophobicContact CG2-CG2 4.22Å
71	S	85.5	Confident	86.4	Confident	11 Å²	11	34.4 Å²	34.4	8%	0.077	18%	0.176	C	C	.	.	H	α-helix	trans	-64.6	-38.4	173	-73.1	0	0	0	0	114.1	I67 F68 M73 K74 Q360 G439 S440	I67-S71 WeakPolarHBondContact O-CB 3.17Å; I67-S71 PolarHBondContact O-N 3.46Å; I67-S71 PolarHBondContact O-OG 3.28Å; F68-S71 PolarHBondContact O-N 3.17Å; S71-M73 PolarHBondContact O-N 3.36Å; S71-K74 PolarHBondContact O-N 3.27Å; S71-Q360 PolarHBondContact OG-NE2 3.08Å; S71-G439 WeakPolarHBondContact OG-CA 3.01Å; S71-S440 PolarHBondContact OG-N 2.92Å
72	Y	84.9	Confident	86.4	Confident	68 Å²	68	42.3 Å²	42.3	27%	0.267	21%	0.212	S	C	.	.	H	α-helix	trans	-74.4	-14.2	-172.5	-175	-96.4	0	0	0	112.6	E9 F68 L69 V70 K74 K81 W83	E9-Y72 PolarHBondContact OE2-OH 2.88Å; F68-Y72 HydrophobicContact CE1-CG 4.31Å; F68-Y72 HydrophobicContact CE2-CD2 4.1Å; F68-Y72 HydrophobicContact CE2-CG 4.46Å; F68-Y72 AromaticContact CZ-CD2 3.74Å; F68-Y72 HydrophobicContact CZ-CD2 3.74Å; F68-Y72 HydrophobicContact CZ-CE2 4.42Å; F68-Y72 AromaticContact CZ-CG 3.94Å; F68-Y72 HydrophobicContact CZ-CG 3.94Å; F68-Y72 WeakPolarHBondContact O-CB 3.34Å; F68-Y72 PolarHBondContact O-N 2.95Å; L69-Y72 PolarHBondContact O-N 3.3Å; V70-Y72 PolarHBondContact O-N 2.87Å; Y72-K74 PolarHBondContact O-N 2.93Å; Y72-K81 HydrophobicContact CE1-CD 4.49Å; Y72-K81 VanDerWaalsContact O-CD 3.22Å; Y72-K81 WeakPolarHBondContact O-CD 3.45Å; Y72-K81 WeakPolarHBondContact O-CE 2.92Å; Y72-K81 PolarHBondContact O-NZ 3.47Å; Y72-W83 HydrophobicContact CD1-CH2 4.25Å; Y72-W83 AromaticContact CD1-CZ2 3.47Å; Y72-W83 HydrophobicContact CD1-CZ2 3.47Å; Y72-W83 VanDerWaalsContact CD1-CZ2 3.47Å; Y72-W83 AromaticContact CE1-CZ2 3.7Å; Y72-W83 HydrophobicContact CE1-CZ2 3.7Å; Y72-W83 AromaticContact CE1-NE1 3.91Å
73	M	85.5	Confident	86.1	Confident	1 Å²	1	44.8 Å²	44.8	1%	0.005	22%	0.22	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.4	-22.4	176.1	-72.4	177.3	-167.6	0	0	113.8	L69 S71 Y80 K81 W83 A84 R90 I93 E94	L69-M73 WeakPolarHBondContact O-CG 3.37Å; L69-M73 PolarHBondContact O-N 2.89Å; S71-M73 PolarHBondContact O-N 3.36Å; M73-Y80 HydrophobicContact CB-CD1 4.31Å; M73-Y80 HydrophobicContact CB-CE1 4.43Å; M73-K81 PolarHBondContact O-N 3.44Å; M73-W83 HydrophobicContact CB-CH2 4.22Å; M73-W83 HydrophobicContact CG-CH2 3.53Å; M73-W83 HydrophobicContact CG-CZ2 4.35Å; M73-W83 HydrophobicContact CG-CZ3 4.11Å; M73-A84 HydrophobicContact CB-CB 4.04Å; M73-A84 HydrophobicContact CG-CB 4.22Å; M73-R90 HydrophobicContact SD-CG 4.21Å; M73-I93 HydrophobicContact CE-CB 4.35Å; M73-I93 HydrophobicContact CE-CG2 3.93Å; M73-E94 HydrophobicContact CE-CG 4.27Å
74	K	87.1	Confident	86	Confident	13 Å²	13	44.7 Å²	44.7	6%	0.057	22%	0.22	C	C	.	.	B	Isolated β-bridge	trans	-116.2	154.3	-174.1	-70.4	-167.4	165.8	-146.6	0	113.9	S71 Y72 G78 T79 Y80 Q441 K442 E473	S71-K74 PolarHBondContact O-N 3.27Å; Y72-K74 PolarHBondContact O-N 2.93Å; K74-G78 PolarHBondContact NZ-O 3.36Å; K74-T79 WeakPolarHBondContact CA-O 3.45Å; K74-Y80 HydrophobicContact CD-CE1 4.38Å; K74-Y80 HydrophobicContact CG-CD1 3.8Å; K74-Y80 HydrophobicContact CG-CE1 3.91Å; K74-Y80 HydrophobicContact CG-CG 4.45Å; K74-Q441 HydrophobicContact CD-CB 4.44Å; K74-Q441 HydrophobicContact CD-CG 4.38Å; K74-K442 WeakPolarHBondContact CD-O 3.47Å; K74-K442 PolarHBondContact NZ-O 2.88Å; K74-E473 WeakPolarHBondContact CE-O 3.33Å; K74-E473 PolarHBondContact NZ-O 3.2Å
75	Y	86.3	Confident	85.9	Confident	103 Å²	103	47.7 Å²	47.7	40%	0.404	24%	0.244	S	C	.	.			trans	-79.8	160.1	165.1	-71.2	-68.4	0	0	0	110.9	N77 G78 T79 K81	Y75-N77 PolarHBondContact O-N 2.97Å; Y75-G78 PolarHBondContact O-N 3.32Å; Y75-T79 PolarHBondContact N-O 3.36Å; Y75-K81 HydrophobicContact CD1-CG 4.24Å; Y75-K81 HydrophobicContact CD2-CG 4.02Å; Y75-K81 HydrophobicContact CE1-CD 4.47Å; Y75-K81 HydrophobicContact CE1-CG 3.99Å; Y75-K81 HydrophobicContact CE2-CB 4.15Å; Y75-K81 HydrophobicContact CE2-CG 3.8Å; Y75-K81 HydrophobicContact CG-CG 4.24Å
76	P	83.9	Confident	85.9	Confident	99 Å²	99	51 Å²	51	64%	0.643	26%	0.261	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.2	-21	171.4	-25.9	35.4	0	0	0	114.2	G78	P76-G78 VanDerWaalsContact C-N 3.25Å; P76-G78 PolarHBondContact O-N 3.42Å
77	N	84.5	Confident	85.6	Confident	111 Å²	111	55.8 Å²	55.8	59%	0.594	29%	0.286	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.4	-0.2	176.4	-62.3	-5.9	0	0	0	113.3	Y75 T79 L444 T462	Y75-N77 PolarHBondContact O-N 2.97Å; N77-T79 VanDerWaalsContact C-N 3.33Å; N77-T79 PolarHBondContact O-N 2.83Å; N77-L444 VanDerWaalsContact O-CD2 3.26Å; N77-L444 WeakPolarHBondContact O-CD2 3.44Å; N77-T462 WeakPolarHBondContact O-CG2 3.33Å
78	G	83.8	Confident	85.5	Confident	4 Å²	4	63.5 Å²	63.5	4%	0.041	32%	0.322	C	S	.	.	S	Bend	trans	85.9	-7.3	177.1	0	0	0	0	0	115.9	K74 Y75 P76 K442	K74-G78 PolarHBondContact NZ-O 3.36Å; Y75-G78 PolarHBondContact O-N 3.32Å; P76-G78 VanDerWaalsContact C-N 3.25Å; P76-G78 PolarHBondContact O-N 3.42Å; G78-K442 WeakPolarHBondContact CA-O 3.21Å
79	T	88.4	Confident	85.5	Confident	63 Å²	63	63.1 Å²	63.1	39%	0.387	32%	0.324	S	S	.	.	P	Polyproline II helix	trans	-81.2	148.3	174.3	55.9	0	0	0	0	111.9	K74 Y75 N77 L444	K74-T79 WeakPolarHBondContact CA-O 3.45Å; Y75-T79 PolarHBondContact N-O 3.36Å; N77-T79 VanDerWaalsContact C-N 3.33Å; N77-T79 PolarHBondContact O-N 2.83Å; T79-L444 HydrophobicContact CG2-CD1 3.72Å
80	Y	87.8	Confident	85.6	Confident	49 Å²	49	61.9 Å²	61.9	19%	0.192	32%	0.317	C	S	.	.	B	Isolated β-bridge	trans	-66.3	145.4	173.1	-73.9	-73.4	0	0	0	111.6	M73 K74 A84 R90 D472 E473	M73-Y80 HydrophobicContact CB-CD1 4.31Å; M73-Y80 HydrophobicContact CB-CE1 4.43Å; K74-Y80 HydrophobicContact CD-CE1 4.38Å; K74-Y80 HydrophobicContact CG-CD1 3.8Å; K74-Y80 HydrophobicContact CG-CE1 3.91Å; K74-Y80 HydrophobicContact CG-CG 4.45Å; Y80-A84 HydrophobicContact CD1-CB 4.26Å; Y80-R90 PolarHBondContact OH-NH1 2.88Å; Y80-D472 PolarHBondContact OH-O 3.31Å; Y80-E473 PolarHBondContact OH-O 3.48Å
81	K	87.6	Confident	85.5	Confident	28 Å²	28	63.1 Å²	63.1	12%	0.122	33%	0.33	C	S	.	.	P	Polyproline II helix	trans	-66.3	154.8	170	-67.2	-174	-177.1	164.7	0	110.3	Y72 M73 Y75 W83 A84 A85	Y72-K81 HydrophobicContact CE1-CD 4.49Å; Y72-K81 VanDerWaalsContact O-CD 3.22Å; Y72-K81 WeakPolarHBondContact O-CD 3.45Å; Y72-K81 WeakPolarHBondContact O-CE 2.92Å; Y72-K81 PolarHBondContact O-NZ 3.47Å; M73-K81 PolarHBondContact O-N 3.44Å; Y75-K81 HydrophobicContact CD1-CG 4.24Å; Y75-K81 HydrophobicContact CD2-CG 4.02Å; Y75-K81 HydrophobicContact CE1-CD 4.47Å; Y75-K81 HydrophobicContact CE1-CG 3.99Å; Y75-K81 HydrophobicContact CE2-CB 4.15Å; Y75-K81 HydrophobicContact CE2-CG 3.8Å; Y75-K81 HydrophobicContact CG-CG 4.24Å; K81-W83 HydrophobicContact CB-CG 4.48Å; K81-W83 HydrophobicContact CD-CZ2 4.39Å; K81-W83 PolarHBondContact O-N 3.09Å; K81-W83 VanDerWaalsContact O-N 3.12Å; K81-A84 CarbonylContact O-C 3.42Å; K81-A84 WeakPolarHBondContact O-CA 3.25Å; K81-A84 PolarHBondContact O-N 2.71Å; K81-A85 PolarHBondContact O-N 3.01Å
82	Q	87.3	Confident	85.5	Confident	175 Å²	175	68.8 Å²	68.8	82%	0.818	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.8	-36.5	-176.6	-68.6	-177.2	-15	0	0	113.6	A84	Q82-A84 VanDerWaalsContact C-N 3.34Å
83	W	83.4	Confident	85.5	Confident	73 Å²	73	67.8 Å²	67.8	28%	0.277	35%	0.354	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.6	-22.9	177	65.1	-99.2	0	0	0	113.6	Y72 M73 K81 T89 I93	Y72-W83 HydrophobicContact CD1-CH2 4.25Å; Y72-W83 AromaticContact CD1-CZ2 3.47Å; Y72-W83 HydrophobicContact CD1-CZ2 3.47Å; Y72-W83 VanDerWaalsContact CD1-CZ2 3.47Å; Y72-W83 AromaticContact CE1-CZ2 3.7Å; Y72-W83 HydrophobicContact CE1-CZ2 3.7Å; Y72-W83 AromaticContact CE1-NE1 3.91Å; M73-W83 HydrophobicContact CB-CH2 4.22Å; M73-W83 HydrophobicContact CG-CH2 3.53Å; M73-W83 HydrophobicContact CG-CZ2 4.35Å; M73-W83 HydrophobicContact CG-CZ3 4.11Å; K81-W83 HydrophobicContact CB-CG 4.48Å; K81-W83 HydrophobicContact CD-CZ2 4.39Å; K81-W83 PolarHBondContact O-N 3.09Å; K81-W83 VanDerWaalsContact O-N 3.12Å; W83-T89 PolarHBondContact O-OG1 2.93Å; W83-I93 HydrophobicContact CE3-CD1 4.04Å; W83-I93 HydrophobicContact CH2-CD1 4.22Å; W83-I93 HydrophobicContact CZ3-CD1 3.36Å
84	A	85.1	Confident	85.4	Confident	0 Å²	0	68.8 Å²	68.8	0%	0	36%	0.359	C	S	.	.	T	Hydrogen-bonded Turn	trans	-101.3	-0.5	-179.2	0	0	0	0	0	113	M73 Y80 K81 Q82 N86 R90	M73-A84 HydrophobicContact CB-CB 4.04Å; M73-A84 HydrophobicContact CG-CB 4.22Å; Y80-A84 HydrophobicContact CD1-CB 4.26Å; K81-A84 CarbonylContact O-C 3.42Å; K81-A84 WeakPolarHBondContact O-CA 3.25Å; K81-A84 PolarHBondContact O-N 2.71Å; Q82-A84 VanDerWaalsContact C-N 3.34Å; A84-N86 VanDerWaalsContact C-N 3.27Å; A84-N86 PolarHBondContact O-N 3.5Å; A84-R90 HydrophobicContact CB-CG 4.38Å; A84-R90 WeakPolarHBondContact O-CD 3.26Å; A84-R90 WeakPolarHBondContact O-CG 3.4Å
85	A	84.3	Confident	85.4	Confident	64 Å²	64	69.7 Å²	69.7	53%	0.529	37%	0.368	S	S	.	.	S	Bend	trans	-68.8	-28.5	-179.8	0	0	0	0	0	112.2	K81	K81-A85 PolarHBondContact O-N 3.01Å
86	N	85.5	Confident	85.4	Confident	106 Å²	106	69.4 Å²	69.4	57%	0.567	38%	0.378	S	S	*	.	S	Bend	trans	-82.1	132.1	176.1	-68.1	-8.9	0	0	0	110.4	A84 E88 T89 R90	A84-N86 VanDerWaalsContact C-N 3.27Å; A84-N86 PolarHBondContact O-N 3.5Å; N86-E88 VanDerWaalsContact C-N 3.29Å; N86-E88 PolarHBondContact O-N 3.05Å; N86-T89 HydrophobicContact CB-CG2 4.27Å; N86-T89 PolarHBondContact O-N 2.93Å; N86-T89 PolarHBondContact O-OG1 2.97Å; N86-R90 PolarHBondContact O-N 3.28Å
87	N	83.8	Confident	85.6	Confident	101 Å²	101	65.3 Å²	65.3	54%	0.54	35%	0.351	S	S	.	.	H	α-helix	trans	-64.9	-34.6	179.8	-160.5	15.2	0	0	0	112.3	T89 R90 G91	N87-T89 PolarHBondContact O-N 3.19Å; N87-R90 PolarHBondContact O-N 3.49Å; N87-G91 PolarHBondContact O-N 2.89Å
88	E	85.3	Confident	85.8	Confident	161 Å²	161	61.8 Å²	61.8	75%	0.752	33%	0.332	S	S	*	.	H	α-helix	trans	-63.7	-40.5	179.4	-64.9	-174.7	173.7	0	0	113.1	N86 G91 Q92	N86-E88 VanDerWaalsContact C-N 3.29Å; N86-E88 PolarHBondContact O-N 3.05Å; E88-G91 PolarHBondContact O-N 3.07Å; E88-Q92 WeakPolarHBondContact O-CG 3.35Å; E88-Q92 PolarHBondContact O-N 3.49Å
89	T	85.4	Confident	86	Confident	44 Å²	44	67.7 Å²	67.7	27%	0.27	35%	0.354	S	S	.	.	H	α-helix	trans	-70	-37	-179.4	56.7	0	0	0	0	111.3	W83 N86 N87 Q92 I93	W83-T89 PolarHBondContact O-OG1 2.93Å; N86-T89 HydrophobicContact CB-CG2 4.27Å; N86-T89 PolarHBondContact O-N 2.93Å; N86-T89 PolarHBondContact O-OG1 2.97Å; N87-T89 PolarHBondContact O-N 3.19Å; T89-Q92 PolarHBondContact O-N 3.17Å; T89-I93 PolarHBondContact O-N 3.08Å
90	R	85.4	Confident	86.1	Confident	22 Å²	22	65.9 Å²	65.9	8%	0.083	35%	0.348	C	S	.	.	H	α-helix	trans	-59.3	-51.4	170.8	-72.6	170.7	43.8	-165.9	-12.3	111.1	M73 Y80 A84 N86 N87 Q92 I93 E94 D472	M73-R90 HydrophobicContact SD-CG 4.21Å; Y80-R90 PolarHBondContact OH-NH1 2.88Å; A84-R90 HydrophobicContact CB-CG 4.38Å; A84-R90 WeakPolarHBondContact O-CD 3.26Å; A84-R90 WeakPolarHBondContact O-CG 3.4Å; N86-R90 PolarHBondContact O-N 3.28Å; N87-R90 PolarHBondContact O-N 3.49Å; R90-Q92 VanDerWaalsContact C-N 3.29Å; R90-Q92 PolarHBondContact O-N 3.39Å; R90-I93 PolarHBondContact O-N 3.48Å; R90-I93 VanDerWaalsContact O-N 3.16Å; R90-E94 WeakPolarHBondContact O-CB 3.13Å; R90-E94 WeakPolarHBondContact O-CG 3.35Å; R90-E94 PolarHBondContact O-N 3.19Å; R90-D472 PolarHBondContact NH1-O 3.28Å
91	G	84.1	Confident	86.2	Confident	30 Å²	30	63.7 Å²	63.7	31%	0.309	34%	0.339	S	S	.	.	H	α-helix	trans	-58.3	-37.7	179.2	0	0	0	0	0	113.2	N87 E88 A95	N87-G91 PolarHBondContact O-N 2.89Å; E88-G91 PolarHBondContact O-N 3.07Å; G91-A95 WeakPolarHBondContact O-CB 3.36Å; G91-A95 PolarHBondContact O-N 3.07Å
92	Q	85.9	Confident	86.3	Confident	129 Å²	129	66.9 Å²	66.9	60%	0.603	35%	0.351	S	S	*	.	H	α-helix	trans	-65.2	-42.9	176	-75	177.8	-3.7	0	0	113.2	E88 T89 R90 T96	E88-Q92 WeakPolarHBondContact O-CG 3.35Å; E88-Q92 PolarHBondContact O-N 3.49Å; T89-Q92 PolarHBondContact O-N 3.17Å; R90-Q92 VanDerWaalsContact C-N 3.29Å; R90-Q92 PolarHBondContact O-N 3.39Å; Q92-T96 WeakPolarHBondContact O-CB 3.41Å; Q92-T96 PolarHBondContact O-N 3.36Å; Q92-T96 PolarHBondContact O-OG1 2.86Å
93	I	84.7	Confident	86.6	Confident	48 Å²	48	62.1 Å²	62.1	25%	0.246	33%	0.334	C	S	.	.	H	α-helix	trans	-67.5	-46.6	178.8	-69.8	164.8	0	0	0	110.1	L69 M73 W83 T89 R90 A95 T96 V97	L69-I93 HydrophobicContact CD1-CG2 4.4Å; L69-I93 HydrophobicContact CD2-CG2 4.3Å; M73-I93 HydrophobicContact CE-CB 4.35Å; M73-I93 HydrophobicContact CE-CG2 3.93Å; W83-I93 HydrophobicContact CE3-CD1 4.04Å; W83-I93 HydrophobicContact CH2-CD1 4.22Å; W83-I93 HydrophobicContact CZ3-CD1 3.36Å; T89-I93 PolarHBondContact O-N 3.08Å; R90-I93 PolarHBondContact O-N 3.48Å; R90-I93 VanDerWaalsContact O-N 3.16Å; I93-A95 VanDerWaalsContact C-N 3.33Å; I93-A95 PolarHBondContact O-N 2.97Å; I93-T96 WeakPolarHBondContact O-CB 3.32Å; I93-T96 PolarHBondContact O-N 3.38Å; I93-T96 VanDerWaalsContact O-N 3.13Å; I93-V97 PolarHBondContact O-N 3.36Å; I93-V97 VanDerWaalsContact O-N 3.08Å
94	E	84.7	Confident	87	Confident	21 Å²	21	60.1 Å²	60.1	10%	0.098	33%	0.328	C	S	.	.	H	α-helix	trans	-59.6	-42.7	176.6	-75.3	168.9	-174.1	0	0	112	M73 R90 T96 V97 L98 R478	M73-E94 HydrophobicContact CE-CG 4.27Å; R90-E94 WeakPolarHBondContact O-CB 3.13Å; R90-E94 WeakPolarHBondContact O-CG 3.35Å; R90-E94 PolarHBondContact O-N 3.19Å; E94-T96 VanDerWaalsContact C-N 3.34Å; E94-T96 PolarHBondContact O-N 3.22Å; E94-V97 PolarHBondContact O-N 2.97Å; E94-L98 WeakPolarHBondContact O-CB 3.42Å; E94-L98 PolarHBondContact O-N 2.98Å; E94-R478 VanDerWaalsContact CD-NH2 3.26Å; E94-R478 IonicContact OE2-CZ 3.49Å; E94-R478 IonicContact OE2-NH2 3.04Å; E94-R478 PolarHBondContact OE2-NH2 2.96Å
95	A	85.3	Confident	87.4	Confident	32 Å²	32	60.1 Å²	60.1	26%	0.264	33%	0.329	S	S	.	.	H	α-helix	trans	-64.2	-38.1	174.7	0	0	0	0	0	112.1	G91 I93 L98 Y99	G91-A95 WeakPolarHBondContact O-CB 3.36Å; G91-A95 PolarHBondContact O-N 3.07Å; I93-A95 VanDerWaalsContact C-N 3.33Å; I93-A95 PolarHBondContact O-N 2.97Å; A95-L98 PolarHBondContact O-N 3.45Å; A95-Y99 HydrophobicContact CB-CD2 4.48Å; A95-Y99 HydrophobicContact CB-CE2 4.15Å; A95-Y99 WeakPolarHBondContact O-CD2 3.29Å; A95-Y99 PolarHBondContact O-N 2.84Å
96	T	87.9	Confident	87.9	Confident	98 Å²	98	59.1 Å²	59.1	60%	0.601	32%	0.317	S	S	*	.	H	α-helix	trans	-62.3	-46	177.8	-58.8	0	0	0	0	111.3	Q92 I93 E94 Y99 G100	Q92-T96 WeakPolarHBondContact O-CB 3.41Å; Q92-T96 PolarHBondContact O-N 3.36Å; Q92-T96 PolarHBondContact O-OG1 2.86Å; I93-T96 WeakPolarHBondContact O-CB 3.32Å; I93-T96 PolarHBondContact O-N 3.38Å; I93-T96 VanDerWaalsContact O-N 3.13Å; E94-T96 VanDerWaalsContact C-N 3.34Å; E94-T96 PolarHBondContact O-N 3.22Å; T96-Y99 PolarHBondContact O-N 2.99Å; T96-G100 PolarHBondContact O-N 2.91Å
97	V	88.3	Confident	88.4	Confident	12 Å²	12	57.1 Å²	57.1	7%	0.073	31%	0.306	C	S	.	.	H	α-helix	trans	-63.5	-43.4	175.6	177.9	0	0	0	0	110.8	D66 L69 I93 E94 Y99 G100 Y101 R478	D66-V97 HydrophobicContact CB-CG1 4.04Å; L69-V97 HydrophobicContact CD1-CG2 3.34Å; I93-V97 PolarHBondContact O-N 3.36Å; I93-V97 VanDerWaalsContact O-N 3.08Å; E94-V97 PolarHBondContact O-N 2.97Å; V97-Y99 PolarHBondContact O-N 3.38Å; V97-G100 WeakPolarHBondContact O-CA 3.16Å; V97-G100 PolarHBondContact O-N 2.74Å; V97-G100 VanDerWaalsContact O-N 3.1Å; V97-Y101 HydrophobicContact CG1-CD2 3.89Å; V97-Y101 HydrophobicContact CG1-CE2 3.64Å; V97-Y101 WeakPolarHBondContact O-CD2 3.3Å; V97-Y101 PolarHBondContact O-N 3.4Å; V97-R478 HydrophobicContact CG1-CB 4.38Å; V97-R478 HydrophobicContact CG1-CG 4.45Å
98	L	87	Confident	88.9	Confident	38 Å²	38	52.3 Å²	52.3	20%	0.199	28%	0.281	C	S	.	.	H	α-helix	trans	-59.5	-44.3	177.1	-177.4	65.7	0	0	0	112.2	E94 A95 G100 Y101 Y102 L190	E94-L98 WeakPolarHBondContact O-CB 3.42Å; E94-L98 PolarHBondContact O-N 2.98Å; A95-L98 PolarHBondContact O-N 3.45Å; L98-G100 VanDerWaalsContact C-N 3.29Å; L98-G100 PolarHBondContact O-N 2.9Å; L98-Y101 PolarHBondContact O-N 2.91Å; L98-Y102 WeakPolarHBondContact O-CB 3.43Å; L98-Y102 PolarHBondContact O-N 3.22Å; L98-L190 HydrophobicContact CD1-CD1 4.23Å
99	Y	88.2	Confident	89.4	Confident	128 Å²	128	45.1 Å²	45.1	50%	0.502	25%	0.247	S	C	.	.	H	α-helix	trans	-65	-33	174.9	-70.5	-52.1	0	0	0	112.4	A95 T96 V97 Y102 T103	A95-Y99 HydrophobicContact CB-CD2 4.48Å; A95-Y99 HydrophobicContact CB-CE2 4.15Å; A95-Y99 WeakPolarHBondContact O-CD2 3.29Å; A95-Y99 PolarHBondContact O-N 2.84Å; T96-Y99 PolarHBondContact O-N 2.99Å; V97-Y99 PolarHBondContact O-N 3.38Å; Y99-Y102 PolarHBondContact O-N 3.46Å; Y99-T103 WeakPolarHBondContact O-CB 3.46Å; Y99-T103 PolarHBondContact O-N 2.99Å; Y99-T103 PolarHBondContact O-OG1 2.95Å
100	G	90.3	Very high	89.8	Confident	25 Å²	25	48 Å²	48	26%	0.258	26%	0.256	S	S	.	.	H	α-helix	trans	-58.8	-53.3	171.1	0	0	0	0	0	112	T96 V97 L98 Y102 T103 L104	T96-G100 PolarHBondContact O-N 2.91Å; V97-G100 WeakPolarHBondContact O-CA 3.16Å; V97-G100 PolarHBondContact O-N 2.74Å; V97-G100 VanDerWaalsContact O-N 3.1Å; L98-G100 VanDerWaalsContact C-N 3.29Å; L98-G100 PolarHBondContact O-N 2.9Å; G100-Y102 PolarHBondContact O-N 2.84Å; G100-T103 PolarHBondContact O-N 2.92Å; G100-L104 WeakPolarHBondContact O-CG 3.26Å; G100-L104 PolarHBondContact O-N 3.13Å
101	Y	91.1	Very high	90.3	Very high	2 Å²	2	47.3 Å²	47.3	1%	0.008	26%	0.255	C	S	.	.	H	α-helix	trans	-59.8	-45.3	174.8	-80.5	-66.4	0	0	0	112.3	L62 L63 D66 V97 L98 T103 L104 Y105 T479	L62-Y101 HydrophobicContact CB-CE1 4.1Å; L62-Y101 HydrophobicContact CD2-CD1 3.81Å; L62-Y101 HydrophobicContact CD2-CD2 3.82Å; L62-Y101 HydrophobicContact CD2-CE1 3.69Å; L62-Y101 HydrophobicContact CD2-CE2 3.68Å; L62-Y101 HydrophobicContact CD2-CG 3.85Å; L62-Y101 HydrophobicContact CG-CD2 4.47Å; L62-Y101 HydrophobicContact CG-CE1 4.02Å; L62-Y101 HydrophobicContact CG-CE2 3.84Å; L62-Y101 PolarHBondContact O-OH 2.9Å; L63-Y101 VanDerWaalsContact CA-OH 3.22Å; L63-Y101 WeakPolarHBondContact CA-OH 3.45Å; L63-Y101 PolarHBondContact N-OH 3.48Å; L63-Y101 VanDerWaalsContact N-OH 3.08Å; D66-Y101 HydrophobicContact CB-CE2 4.13Å; V97-Y101 HydrophobicContact CG1-CD2 3.89Å; V97-Y101 HydrophobicContact CG1-CE2 3.64Å; V97-Y101 WeakPolarHBondContact O-CD2 3.3Å; V97-Y101 PolarHBondContact O-N 3.4Å; L98-Y101 PolarHBondContact O-N 2.91Å; Y101-T103 VanDerWaalsContact C-N 3.29Å; Y101-T103 PolarHBondContact O-N 3.23Å; Y101-L104 PolarHBondContact O-N 3.05Å; Y101-Y105 HydrophobicContact CD1-CD2 4.36Å; Y101-Y105 AromaticContact CD1-CE2 3.61Å; Y101-Y105 HydrophobicContact CD1-CE2 3.61Å; Y101-Y105 AromaticContact CD1-CZ 3.77Å; Y101-Y105 HydrophobicContact CG-CE2 4.16Å; Y101-Y105 VanDerWaalsContact O-CB 3.27Å; Y101-Y105 WeakPolarHBondContact O-CB 3.06Å; Y101-Y105 VanDerWaalsContact O-CD2 3.27Å; Y101-Y105 WeakPolarHBondContact O-CD2 3.45Å; Y101-Y105 PolarHBondContact O-N 3.44Å; Y101-T479 HydrophobicContact CE1-CG2 4.42Å; Y101-T479 VanDerWaalsContact CE2-OG1 3.24Å; Y101-T479 WeakPolarHBondContact CE2-OG1 3.38Å; Y101-T479 PolarHBondContact OH-OG1 2.99Å
102	Y	89.8	Confident	90.8	Very high	95 Å²	95	46.3 Å²	46.3	37%	0.373	24%	0.243	S	C	.	.	H	α-helix	trans	-56.8	-45	178.9	-173.9	-97	0	0	0	111.8	L98 Y99 G100 S106 L190 L193	L98-Y102 WeakPolarHBondContact O-CB 3.43Å; L98-Y102 PolarHBondContact O-N 3.22Å; Y99-Y102 PolarHBondContact O-N 3.46Å; G100-Y102 PolarHBondContact O-N 2.84Å; Y102-S106 VanDerWaalsContact O-CB 3.25Å; Y102-S106 WeakPolarHBondContact O-CB 3.27Å; Y102-S106 PolarHBondContact O-N 3.16Å; Y102-S106 PolarHBondContact O-OG 3.19Å; Y102-L190 HydrophobicContact CD2-CD1 4.49Å; Y102-L193 HydrophobicContact CD2-CD1 4.48Å; Y102-L193 HydrophobicContact CD2-CD2 3.94Å; Y102-L193 HydrophobicContact CE2-CB 4.45Å; Y102-L193 HydrophobicContact CE2-CD1 4.2Å; Y102-L193 HydrophobicContact CE2-CD2 4.38Å
103	T	92.2	Very high	91.3	Very high	76 Å²	76	41 Å²	41	47%	0.466	22%	0.218	S	C	.	.	H	α-helix	trans	-66.9	-50.5	179.5	-55.9	0	0	0	0	111.1	Y99 G100 Y101 S106 I107	Y99-T103 WeakPolarHBondContact O-CB 3.46Å; Y99-T103 PolarHBondContact O-N 2.99Å; Y99-T103 PolarHBondContact O-OG1 2.95Å; G100-T103 PolarHBondContact O-N 2.92Å; Y101-T103 VanDerWaalsContact C-N 3.29Å; Y101-T103 PolarHBondContact O-N 3.23Å; T103-S106 PolarHBondContact O-N 3.29Å; T103-I107 HydrophobicContact CG2-CD1 3.99Å; T103-I107 VanDerWaalsContact O-CG1 3.26Å; T103-I107 WeakPolarHBondContact O-CG1 3.4Å; T103-I107 PolarHBondContact O-N 3.01Å
104	L	93.6	Very high	91.8	Very high	30 Å²	30	41.7 Å²	41.7	16%	0.157	22%	0.221	C	C	.	.	H	α-helix	trans	-64.2	-43.4	-178	-71	173.4	0	0	0	112.4	I58 T59 L62 G100 Y101 I107 I108	I58-L104 HydrophobicContact CG2-CD1 4.17Å; I58-L104 HydrophobicContact CG2-CD2 4.07Å; T59-L104 HydrophobicContact CG2-CB 4.29Å; L62-L104 HydrophobicContact CD2-CD1 3.9Å; G100-L104 WeakPolarHBondContact O-CG 3.26Å; G100-L104 PolarHBondContact O-N 3.13Å; Y101-L104 PolarHBondContact O-N 3.05Å; L104-I107 PolarHBondContact O-N 2.91Å; L104-I108 WeakPolarHBondContact O-CG1 3.45Å; L104-I108 PolarHBondContact O-N 3.43Å
105	Y	93.4	Very high	92.3	Very high	1 Å²	1	45.3 Å²	45.3	0%	0.004	23%	0.234	C	C	.	.	H	α-helix	trans	-67.4	-35.6	175.9	-71.8	-35.5	0	0	0	112.9	T59 Y101 I107 I108 L109 L193 I197 L422 F482	T59-Y105 HydrophobicContact CG2-CD1 3.9Å; T59-Y105 HydrophobicContact CG2-CE1 3.4Å; Y101-Y105 HydrophobicContact CD1-CD2 4.36Å; Y101-Y105 AromaticContact CD1-CE2 3.61Å; Y101-Y105 HydrophobicContact CD1-CE2 3.61Å; Y101-Y105 AromaticContact CD1-CZ 3.77Å; Y101-Y105 HydrophobicContact CG-CE2 4.16Å; Y101-Y105 VanDerWaalsContact O-CB 3.27Å; Y101-Y105 WeakPolarHBondContact O-CB 3.06Å; Y101-Y105 VanDerWaalsContact O-CD2 3.27Å; Y101-Y105 WeakPolarHBondContact O-CD2 3.45Å; Y101-Y105 PolarHBondContact O-N 3.44Å; Y105-I107 VanDerWaalsContact C-N 3.34Å; Y105-I108 HydrophobicContact CD1-CD1 4.03Å; Y105-I108 WeakPolarHBondContact O-CB 3.47Å; Y105-I108 PolarHBondContact O-N 3.42Å; Y105-L109 PolarHBondContact O-N 3.41Å; Y105-L193 HydrophobicContact CD2-CD2 4.25Å; Y105-L193 HydrophobicContact CG-CD2 4.4Å; Y105-I197 HydrophobicContact CD1-CD1 3.92Å; Y105-I197 HydrophobicContact CD1-CG1 4.2Å; Y105-I197 HydrophobicContact CD1-CG2 4.24Å; Y105-I197 HydrophobicContact CD2-CG1 4.46Å; Y105-I197 HydrophobicContact CE1-CG2 4.23Å; Y105-I197 HydrophobicContact CG-CD1 4.01Å; Y105-I197 HydrophobicContact CG-CG1 3.94Å; Y105-L422 HydrophobicContact CD1-CD1 4.06Å; Y105-L422 HydrophobicContact CE1-CD1 3.59Å; Y105-F482 AromaticContact CD2-CD1 3.8Å; Y105-F482 HydrophobicContact CD2-CD1 3.8Å; Y105-F482 AromaticContact CD2-CE1 3.39Å; Y105-F482 HydrophobicContact CD2-CE1 3.39Å; Y105-F482 HydrophobicContact CD2-CE2 4.31Å; Y105-F482 HydrophobicContact CD2-CG 4.41Å; Y105-F482 AromaticContact CD2-CZ 3.71Å; Y105-F482 HydrophobicContact CD2-CZ 3.71Å; Y105-F482 AromaticContact CE2-CD1 3.41Å; Y105-F482 HydrophobicContact CE2-CD1 3.41Å; Y105-F482 VanDerWaalsContact CE2-CD1 3.41Å; Y105-F482 AromaticContact CE2-CE1 3.5Å; Y105-F482 HydrophobicContact CE2-CE1 3.5Å; Y105-F482 HydrophobicContact CE2-CG 4.02Å; Y105-F482 HydrophobicContact CE2-CZ 4.21Å; Y105-F482 HydrophobicContact CG-CE1 4.26Å
106	S	93.7	Very high	92.7	Very high	42 Å²	42	44.1 Å²	44.1	29%	0.294	22%	0.223	S	C	.	.	H	α-helix	trans	-63	-42.1	172.4	-62.1	0	0	0	0	111.5	Y102 T103 I108 L109 F110 L193	Y102-S106 VanDerWaalsContact O-CB 3.25Å; Y102-S106 WeakPolarHBondContact O-CB 3.27Å; Y102-S106 PolarHBondContact O-N 3.16Å; Y102-S106 PolarHBondContact O-OG 3.19Å; T103-S106 PolarHBondContact O-N 3.29Å; S106-I108 VanDerWaalsContact C-N 3.34Å; S106-L109 PolarHBondContact O-N 3.06Å; S106-F110 WeakPolarHBondContact O-CB 3.49Å; S106-F110 PolarHBondContact O-N 3.17Å; S106-L193 VanDerWaalsContact OG-CD1 3.26Å; S106-L193 WeakPolarHBondContact OG-CD1 3.26Å
107	I	95.7	Very high	93	Very high	64 Å²	64	39.8 Å²	39.8	33%	0.328	20%	0.197	S	C	.	.	H	α-helix	trans	-64	-40.5	174.7	-64.4	165.3	0	0	0	110.4	I55 T103 L104 Y105 L109 F110 C111	I55-I107 HydrophobicContact CD1-CG2 3.46Å; I55-I107 VanDerWaalsContact CD1-CG2 3.46Å; I55-I107 HydrophobicContact CG1-CG2 4.16Å; I55-I107 HydrophobicContact CG2-CB 4.43Å; I55-I107 HydrophobicContact CG2-CG2 3.99Å; T103-I107 HydrophobicContact CG2-CD1 3.99Å; T103-I107 VanDerWaalsContact O-CG1 3.26Å; T103-I107 WeakPolarHBondContact O-CG1 3.4Å; T103-I107 PolarHBondContact O-N 3.01Å; L104-I107 PolarHBondContact O-N 2.91Å; Y105-I107 VanDerWaalsContact C-N 3.34Å; I107-L109 PolarHBondContact O-N 2.93Å; I107-F110 WeakPolarHBondContact O-CB 3.48Å; I107-F110 PolarHBondContact O-N 2.91Å; I107-C111 WeakPolarHBondContact O-CB 3.18Å; I107-C111 PolarHBondContact O-N 3.47Å; I107-C111 PolarHBondContact O-SG 3.22Å
108	I	95.1	Very high	93.3	Very high	1 Å²	1	41.2 Å²	41.2	1%	0.005	20%	0.202	C	C	.	.	H	α-helix	trans	-59.6	-47.2	175.2	-75.3	166.7	0	0	0	111.2	I55 T59 L104 Y105 S106 F110 C111 V112 I197 L200 L418 L422	I55-I108 HydrophobicContact CG2-CD1 4.4Å; I55-I108 HydrophobicContact CG2-CG1 3.76Å; T59-I108 HydrophobicContact CG2-CD1 4.06Å; T59-I108 WeakPolarHBondContact OG1-CD1 3.18Å; L104-I108 WeakPolarHBondContact O-CG1 3.45Å; L104-I108 PolarHBondContact O-N 3.43Å; Y105-I108 HydrophobicContact CD1-CD1 4.03Å; Y105-I108 WeakPolarHBondContact O-CB 3.47Å; Y105-I108 PolarHBondContact O-N 3.42Å; S106-I108 VanDerWaalsContact C-N 3.34Å; I108-F110 VanDerWaalsContact C-N 3.33Å; I108-F110 PolarHBondContact O-N 3.26Å; I108-C111 PolarHBondContact O-N 2.94Å; I108-V112 HydrophobicContact CG2-CG2 4.35Å; I108-V112 WeakPolarHBondContact O-CG2 3.39Å; I108-V112 PolarHBondContact O-N 3.5Å; I108-I197 HydrophobicContact CG2-CD1 4.37Å; I108-L200 HydrophobicContact CG2-CD1 4.42Å; I108-L418 HydrophobicContact CG2-CD2 3.96Å; I108-L422 HydrophobicContact CD1-CD1 4.39Å
109	L	95	Very high	93.6	Very high	9 Å²	9	39.6 Å²	39.6	5%	0.047	19%	0.194	C	C	.	.	H	α-helix	trans	-60.3	-44.2	176.8	-74.1	173.5	0	0	0	111.5	Y105 S106 I107 C111 V112 F113 L155 L193 I197 L200	Y105-L109 PolarHBondContact O-N 3.41Å; S106-L109 PolarHBondContact O-N 3.06Å; I107-L109 PolarHBondContact O-N 2.93Å; L109-C111 VanDerWaalsContact C-N 3.35Å; L109-C111 PolarHBondContact O-N 3.47Å; L109-V112 PolarHBondContact O-N 2.97Å; L109-F113 HydrophobicContact CD2-CD2 3.94Å; L109-F113 HydrophobicContact CD2-CE2 3.68Å; L109-F113 WeakPolarHBondContact O-CB 3.21Å; L109-F113 PolarHBondContact O-N 2.9Å; L109-L155 HydrophobicContact CD1-CD2 4.4Å; L109-L193 HydrophobicContact CD1-CD1 3.92Å; L109-L193 HydrophobicContact CD1-CG 4.28Å; L109-I197 HydrophobicContact CD1-CD1 4.44Å; L109-I197 HydrophobicContact CD2-CD1 4.19Å; L109-I197 HydrophobicContact CG-CD1 3.96Å; L109-L200 HydrophobicContact CD2-CD1 3.7Å
110	F	95.4	Very high	93.8	Very high	104 Å²	104	36 Å²	36	46%	0.456	18%	0.18	S	C	.	.	H	α-helix	trans	-59.4	-44.7	174.2	175.2	-91.3	0	0	0	111.9	S106 I107 I108 L114 W115	S106-F110 WeakPolarHBondContact O-CB 3.49Å; S106-F110 PolarHBondContact O-N 3.17Å; I107-F110 WeakPolarHBondContact O-CB 3.48Å; I107-F110 PolarHBondContact O-N 2.91Å; I108-F110 VanDerWaalsContact C-N 3.33Å; I108-F110 PolarHBondContact O-N 3.26Å; F110-L114 HydrophobicContact CD2-CB 4.32Å; F110-L114 HydrophobicContact CD2-CD2 3.75Å; F110-L114 HydrophobicContact CE2-CB 4.45Å; F110-L114 HydrophobicContact CE2-CD2 3.21Å; F110-L114 HydrophobicContact CE2-CG 4.37Å; F110-L114 HydrophobicContact CZ-CD2 3.83Å; F110-L114 WeakPolarHBondContact O-CA 3.29Å; F110-L114 WeakPolarHBondContact O-CB 3.48Å; F110-L114 PolarHBondContact O-N 3.24Å; F110-W115 HydrophobicContact CD1-CB 4.17Å; F110-W115 HydrophobicContact CE1-CB 3.78Å; F110-W115 HydrophobicContact CE1-CE3 4.48Å; F110-W115 HydrophobicContact CE1-CG 4.28Å; F110-W115 HydrophobicContact CZ-CB 4.49Å; F110-W115 HydrophobicContact CZ-CE3 4.49Å; F110-W115 PolarHBondContact O-N 3.45Å
111	C	95.1	Very high	93.9	Very high	9 Å²	9	37 Å²	37	6%	0.061	18%	0.177	C	C	.	.	I	π-helix	trans	-62.1	-47.6	177.9	-74.1	0	0	0	0	111.9	I107 I108 L109 I116	I107-C111 WeakPolarHBondContact O-CB 3.18Å; I107-C111 PolarHBondContact O-N 3.47Å; I107-C111 PolarHBondContact O-SG 3.22Å; I108-C111 PolarHBondContact O-N 2.94Å; L109-C111 VanDerWaalsContact C-N 3.35Å; L109-C111 PolarHBondContact O-N 3.47Å; C111-I116 HydrophobicContact CB-CD1 4.44Å; C111-I116 VanDerWaalsContact O-CB 3.26Å; C111-I116 WeakPolarHBondContact O-CB 3.48Å; C111-I116 VanDerWaalsContact O-CG1 3.25Å; C111-I116 WeakPolarHBondContact O-CG1 3.28Å; C111-I116 PolarHBondContact O-N 2.68Å
112	V	95.3	Very high	93.8	Very high	9 Å²	9	40.1 Å²	40.1	6%	0.055	19%	0.189	C	C	.	.	I	π-helix	trans	-72.6	-42.2	-174.6	172.7	0	0	0	0	112.4	I108 L109 P117 L200 L418	I108-V112 HydrophobicContact CG2-CG2 4.35Å; I108-V112 WeakPolarHBondContact O-CG2 3.39Å; I108-V112 PolarHBondContact O-N 3.5Å; L109-V112 PolarHBondContact O-N 2.97Å; V112-P117 WeakPolarHBondContact O-CD 3.22Å; V112-P117 WeakPolarHBondContact O-CG 3.41Å; V112-L200 HydrophobicContact CB-CD1 4.47Å; V112-L200 HydrophobicContact CG1-CD1 4.4Å; V112-L200 HydrophobicContact CG1-CD2 4.03Å; V112-L200 HydrophobicContact CG2-CD1 4.41Å; V112-L418 HydrophobicContact CG2-CD1 4.2Å; V112-L418 HydrophobicContact CG2-CD2 3.66Å
113	F	95.6	Very high	93.5	Very high	18 Å²	18	37.5 Å²	37.5	8%	0.079	18%	0.179	C	C	.	.	I	π-helix	trans	-99.6	-15.5	-172	-69.7	-71.6	0	0	0	115	L109 F147 V150 C151 L154 L200	L109-F113 HydrophobicContact CD2-CD2 3.94Å; L109-F113 HydrophobicContact CD2-CE2 3.68Å; L109-F113 WeakPolarHBondContact O-CB 3.21Å; L109-F113 PolarHBondContact O-N 2.9Å; F113-F147 WeakPolarHBondContact CD1-O 3.48Å; F113-F147 WeakPolarHBondContact O-CB 3.5Å; F113-V150 HydrophobicContact CE1-CB 4.39Å; F113-V150 HydrophobicContact CE1-CG1 3.84Å; F113-C151 HydrophobicContact CB-CB 3.66Å; F113-C151 HydrophobicContact CD1-CB 4.02Å; F113-C151 HydrophobicContact CD2-CB 3.87Å; F113-C151 HydrophobicContact CG-CB 3.59Å; F113-L154 HydrophobicContact CE1-CD1 4.28Å; F113-L154 HydrophobicContact CE2-CD1 4.18Å; F113-L154 HydrophobicContact CZ-CD1 3.55Å; F113-L200 HydrophobicContact CE2-CD1 4.09Å; F113-L200 HydrophobicContact CE2-CD2 3.92Å; F113-L200 HydrophobicContact CE2-CG 4.23Å; F113-L200 HydrophobicContact CZ-CD2 3.78Å; F113-L200 HydrophobicContact CZ-CG 4.47Å
114	L	94.7	Very high	93.2	Very high	61 Å²	61	38.8 Å²	38.8	32%	0.319	18%	0.18	S	C	.	.	I	π-helix	trans	-122.3	-61.7	179.6	-168.7	78.1	0	0	0	111.9	F110 F118 T144 V148	F110-L114 HydrophobicContact CD2-CB 4.32Å; F110-L114 HydrophobicContact CD2-CD2 3.75Å; F110-L114 HydrophobicContact CE2-CB 4.45Å; F110-L114 HydrophobicContact CE2-CD2 3.21Å; F110-L114 HydrophobicContact CE2-CG 4.37Å; F110-L114 HydrophobicContact CZ-CD2 3.83Å; F110-L114 WeakPolarHBondContact O-CA 3.29Å; F110-L114 WeakPolarHBondContact O-CB 3.48Å; F110-L114 PolarHBondContact O-N 3.24Å; L114-F118 WeakPolarHBondContact O-CB 3.42Å; L114-F118 PolarHBondContact O-N 2.89Å; L114-T144 HydrophobicContact CD1-CG2 3.91Å; L114-T144 WeakPolarHBondContact O-CG2 3.37Å; L114-V148 HydrophobicContact CD1-CG2 3.36Å
115	W	95.1	Very high	92.7	Very high	98 Å²	98	39.9 Å²	39.9	37%	0.371	18%	0.184	S	C	.	.	I	π-helix	trans	-73.4	-49.1	-165.6	-171.8	-105.5	0	0	0	113.7	T48 F110 F118 V119	T48-W115 PolarHBondContact OG1-NE1 3.37Å; F110-W115 HydrophobicContact CD1-CB 4.17Å; F110-W115 HydrophobicContact CE1-CB 3.78Å; F110-W115 HydrophobicContact CE1-CE3 4.48Å; F110-W115 HydrophobicContact CE1-CG 4.28Å; F110-W115 HydrophobicContact CZ-CB 4.49Å; F110-W115 HydrophobicContact CZ-CE3 4.49Å; F110-W115 PolarHBondContact O-N 3.45Å; W115-F118 HydrophobicContact CE3-CD1 4.48Å; W115-F118 HydrophobicContact CZ3-CD1 4.41Å; W115-F118 PolarHBondContact O-N 3.38Å; W115-V119 HydrophobicContact CD2-CG2 4.29Å; W115-V119 HydrophobicContact CZ2-CG2 4.17Å; W115-V119 VanDerWaalsContact O-CG2 3.31Å; W115-V119 WeakPolarHBondContact O-CG2 3.46Å; W115-V119 PolarHBondContact O-N 3.31Å
116	I	94.3	Very high	91.8	Very high	7 Å²	7	44.1 Å²	44.1	4%	0.036	20%	0.202	C	C	.	.	H	α-helix	trans	-63	-48.7	178.6	-66.1	168.6	0	0	0	111	T48 A52 C111 F118 V119 Y120 L411 M415	T48-I116 HydrophobicContact CG2-CG1 4.21Å; A52-I116 HydrophobicContact CB-CD1 3.96Å; C111-I116 HydrophobicContact CB-CD1 4.44Å; C111-I116 VanDerWaalsContact O-CB 3.26Å; C111-I116 WeakPolarHBondContact O-CB 3.48Å; C111-I116 VanDerWaalsContact O-CG1 3.25Å; C111-I116 WeakPolarHBondContact O-CG1 3.28Å; C111-I116 PolarHBondContact O-N 2.68Å; I116-F118 VanDerWaalsContact C-N 3.33Å; I116-F118 PolarHBondContact O-N 3.13Å; I116-V119 PolarHBondContact O-N 2.81Å; I116-Y120 VanDerWaalsContact O-CB 3.3Å; I116-Y120 WeakPolarHBondContact O-CB 3.47Å; I116-Y120 PolarHBondContact O-N 3.47Å; I116-L411 HydrophobicContact CG2-CB 4.39Å; I116-M415 HydrophobicContact CD1-CB 4.45Å
117	P	94.8	Very high	90.6	Very high	7 Å²	7	47.3 Å²	47.3	5%	0.045	22%	0.216	C	C	.	.	H	α-helix	trans	-59.6	-41.7	175.7	-24.4	34.6	0	0	0	112.6	V112 Y120 F121 T144 F147	V112-P117 WeakPolarHBondContact O-CD 3.22Å; V112-P117 WeakPolarHBondContact O-CG 3.41Å; P117-Y120 WeakPolarHBondContact O-CB 3.38Å; P117-Y120 PolarHBondContact O-N 3.18Å; P117-F121 HydrophobicContact CB-CE2 4.34Å; P117-F121 WeakPolarHBondContact O-CD2 3.37Å; P117-F121 PolarHBondContact O-N 3.32Å; P117-T144 HydrophobicContact CB-CG2 4.4Å; P117-F147 HydrophobicContact CB-CB 4.4Å; P117-F147 HydrophobicContact CB-CD1 4.27Å; P117-F147 HydrophobicContact CB-CD2 3.84Å; P117-F147 HydrophobicContact CB-CE2 4.17Å; P117-F147 HydrophobicContact CB-CG 3.91Å; P117-F147 HydrophobicContact CG-CB 4.17Å; P117-F147 HydrophobicContact CG-CD1 3.79Å; P117-F147 HydrophobicContact CG-CD2 4.25Å; P117-F147 HydrophobicContact CG-CE1 4.23Å; P117-F147 HydrophobicContact CG-CG 3.8Å
118	F	94.3	Very high	89.1	Confident	42 Å²	42	51.9 Å²	51.9	18%	0.184	24%	0.241	C	C	.	.	H	α-helix	trans	-58.7	-50.5	176.3	172.5	-101.3	0	0	0	112.3	L114 W115 I116 Y120 F121 Y122 V137 A140 T144	L114-F118 WeakPolarHBondContact O-CB 3.42Å; L114-F118 PolarHBondContact O-N 2.89Å; W115-F118 HydrophobicContact CE3-CD1 4.48Å; W115-F118 HydrophobicContact CZ3-CD1 4.41Å; W115-F118 PolarHBondContact O-N 3.38Å; I116-F118 VanDerWaalsContact C-N 3.33Å; I116-F118 PolarHBondContact O-N 3.13Å; F118-Y120 VanDerWaalsContact C-N 3.29Å; F118-Y120 PolarHBondContact O-N 2.95Å; F118-F121 PolarHBondContact O-N 3.32Å; F118-Y122 WeakPolarHBondContact O-CB 3.44Å; F118-Y122 PolarHBondContact O-N 3.43Å; F118-V137 HydrophobicContact CE2-CG1 4.26Å; F118-V137 HydrophobicContact CZ-CG1 4.28Å; F118-A140 HydrophobicContact CD2-CB 4.13Å; F118-A140 HydrophobicContact CE2-CB 4.03Å; F118-T144 VanDerWaalsContact CA-OG1 3.24Å; F118-T144 WeakPolarHBondContact CA-OG1 3.41Å; F118-T144 HydrophobicContact CB-CG2 4.14Å; F118-T144 PolarHBondContact N-OG1 2.97Å
119	V	93.7	Very high	87.5	Confident	3 Å²	3	59.3 Å²	59.3	2%	0.018	28%	0.281	C	S	.	.	H	α-helix	trans	-66.6	-34	-180	179.3	0	0	0	0	111.2	V44 T48 W115 I116 Y123 L411	V44-V119 HydrophobicContact CG1-CG1 4.16Å; V44-V119 HydrophobicContact CG1-CG2 4.22Å; T48-V119 HydrophobicContact CG2-CB 4.49Å; T48-V119 HydrophobicContact CG2-CG2 4.29Å; W115-V119 HydrophobicContact CD2-CG2 4.29Å; W115-V119 HydrophobicContact CZ2-CG2 4.17Å; W115-V119 VanDerWaalsContact O-CG2 3.31Å; W115-V119 WeakPolarHBondContact O-CG2 3.46Å; W115-V119 PolarHBondContact O-N 3.31Å; I116-V119 PolarHBondContact O-N 2.81Å; V119-Y123 PolarHBondContact O-N 2.8Å; V119-Y123 VanDerWaalsContact O-N 3.12Å; V119-L411 HydrophobicContact CB-CD1 4.31Å; V119-L411 HydrophobicContact CG1-CD1 3.84Å; V119-L411 HydrophobicContact CG1-CD2 4.43Å
120	Y	91.7	Very high	85.9	Confident	53 Å²	53	62.1 Å²	62.1	21%	0.208	30%	0.296	C	S	.	.	H	α-helix	trans	-61.3	-55.3	174.3	177.7	-87	0	0	0	111.6	I116 P117 F118 Y122 Y123 E124 Y398 Q408	I116-Y120 VanDerWaalsContact O-CB 3.3Å; I116-Y120 WeakPolarHBondContact O-CB 3.47Å; I116-Y120 PolarHBondContact O-N 3.47Å; P117-Y120 WeakPolarHBondContact O-CB 3.38Å; P117-Y120 PolarHBondContact O-N 3.18Å; F118-Y120 VanDerWaalsContact C-N 3.29Å; F118-Y120 PolarHBondContact O-N 2.95Å; Y120-Y122 VanDerWaalsContact C-N 3.34Å; Y120-Y122 PolarHBondContact O-N 3.28Å; Y120-Y123 PolarHBondContact O-N 3.1Å; Y120-E124 PolarHBondContact O-N 3.42Å; Y120-Y398 PolarHBondContact OH-OH 2.86Å; Y120-Q408 HydrophobicContact CD2-CB 4.04Å; Y120-Q408 HydrophobicContact CD2-CG 4.14Å; Y120-Q408 HydrophobicContact CE2-CB 3.71Å; Y120-Q408 HydrophobicContact CE2-CG 3.99Å
121	F	91.4	Very high	84.3	Confident	46 Å²	46	64 Å²	64	20%	0.202	32%	0.316	C	S	.	.	H	α-helix	trans	-69.3	-32.2	-179.6	-69	-61.8	0	0	0	112.8	P117 F118 Y123 E124 E125 A140 Y143 F147	P117-F121 HydrophobicContact CB-CE2 4.34Å; P117-F121 WeakPolarHBondContact O-CD2 3.37Å; P117-F121 PolarHBondContact O-N 3.32Å; F118-F121 PolarHBondContact O-N 3.32Å; F121-Y123 PolarHBondContact O-N 2.94Å; F121-E124 PolarHBondContact O-N 3.39Å; F121-E125 WeakPolarHBondContact O-CB 3.34Å; F121-E125 PolarHBondContact O-N 3.17Å; F121-A140 HydrophobicContact CB-CB 4.14Å; F121-Y143 HydrophobicContact CD1-CD2 4.37Å; F121-Y143 HydrophobicContact CD1-CG 4.26Å; F121-Y143 HydrophobicContact CE1-CG 4.46Å; F121-Y143 HydrophobicContact CG-CG 4.45Å; F121-F147 HydrophobicContact CE2-CD2 4.17Å; F121-F147 AromaticContact CE2-CE2 3.62Å; F121-F147 HydrophobicContact CE2-CE2 3.62Å; F121-F147 AromaticContact CZ-CE2 3.92Å; F121-F147 HydrophobicContact CZ-CE2 3.92Å
122	Y	89.7	Confident	83.4	Confident	67 Å²	67	68.2 Å²	68.2	26%	0.263	34%	0.338	S	S	.	.	H	α-helix	trans	-58.7	-40.7	172.5	179.4	-97	0	0	0	111.1	F118 Y120 Q136 V137	F118-Y122 WeakPolarHBondContact O-CB 3.44Å; F118-Y122 PolarHBondContact O-N 3.43Å; Y120-Y122 VanDerWaalsContact C-N 3.34Å; Y120-Y122 PolarHBondContact O-N 3.28Å; Y122-Q136 HydrophobicContact CD2-CG 3.9Å; Y122-Q136 HydrophobicContact CE2-CB 4.42Å; Y122-Q136 HydrophobicContact CE2-CG 3.86Å; Y122-Q136 PolarHBondContact O-NE2 3.44Å; Y122-V137 HydrophobicContact CD2-CG2 4.17Å; Y122-V137 HydrophobicContact CE2-CG2 3.8Å
123	Y	84.5	Confident	82.7	Confident	41 Å²	41	75 Å²	75	16%	0.161	37%	0.367	C	S	.	.	H	α-helix	trans	-75.8	-37.9	177.4	-173.9	-85	0	0	0	113	E42 V119 Y120 F121 E125 K126 P407 Q408	E42-Y123 HydrophobicContact CB-CD2 4.48Å; E42-Y123 HydrophobicContact CB-CE2 4.42Å; E42-Y123 HydrophobicContact CG-CD2 4.02Å; E42-Y123 HydrophobicContact CG-CE2 3.74Å; V119-Y123 PolarHBondContact O-N 2.8Å; V119-Y123 VanDerWaalsContact O-N 3.12Å; Y120-Y123 PolarHBondContact O-N 3.1Å; F121-Y123 PolarHBondContact O-N 2.94Å; Y123-E125 VanDerWaalsContact C-N 3.31Å; Y123-E125 PolarHBondContact O-N 3.29Å; Y123-K126 WeakPolarHBondContact O-CB 3.33Å; Y123-K126 PolarHBondContact O-N 2.78Å; Y123-K126 VanDerWaalsContact O-N 3.16Å; Y123-P407 HydrophobicContact CD1-CB 4.43Å; Y123-P407 HydrophobicContact CD2-CB 4.1Å; Y123-P407 HydrophobicContact CD2-CG 4.27Å; Y123-P407 HydrophobicContact CE1-CB 4.31Å; Y123-P407 HydrophobicContact CE1-CG 4.28Å; Y123-P407 HydrophobicContact CE2-CB 3.95Å; Y123-P407 HydrophobicContact CE2-CG 3.63Å; Y123-P407 HydrophobicContact CG-CB 4.33Å; Y123-Q408 HydrophobicContact CD1-CG 3.56Å; Y123-Q408 HydrophobicContact CE1-CG 4.16Å; Y123-Q408 HydrophobicContact CG-CG 4.45Å
124	E	85	Confident	82	Confident	103 Å²	103	78.6 Å²	78.6	48%	0.481	39%	0.393	S	S	.	.	H	α-helix	trans	-60.3	-39.7	175.7	-172.2	73.1	-141.9	0	0	112.3	Y120 F121 K126 Q408	Y120-E124 PolarHBondContact O-N 3.42Å; F121-E124 PolarHBondContact O-N 3.39Å; E124-K126 PolarHBondContact O-N 2.68Å; E124-Q408 VanDerWaalsContact CA-NE2 3.33Å; E124-Q408 PolarHBondContact OE2-NE2 2.89Å; E124-Q408 PolarHBondContact OE2-OE1 3.08Å
125	E	83.7	Confident	81.5	Confident	52 Å²	52	77.8 Å²	77.8	24%	0.243	39%	0.392	C	S	.	.	T	Hydrogen-bonded Turn	trans	-79	4.6	179.5	-163.6	70.3	-172.9	0	0	113.1	F121 Y123 D127 Q136 N139	F121-E125 WeakPolarHBondContact O-CB 3.34Å; F121-E125 PolarHBondContact O-N 3.17Å; Y123-E125 VanDerWaalsContact C-N 3.31Å; Y123-E125 PolarHBondContact O-N 3.29Å; E125-D127 PolarHBondContact O-N 2.85Å; E125-Q136 HydrophobicContact CB-CG 4.14Å; E125-Q136 HydrophobicContact CG-CG 4.28Å; E125-N139 HydrophobicContact CG-CB 3.98Å; E125-N139 PolarHBondContact OE1-ND2 2.85Å
126	K	74.9	Confident	81	Confident	90 Å²	90	74 Å²	74	39%	0.391	38%	0.378	S	S	.	.			trans	-76.8	87.9	178.8	-168.4	-170.9	171.3	-167	0	109.7	E42 Y123 E124	E42-K126 IonicContact OE1-NZ 3.93Å; E42-K126 PolarHBondContact OE1-NZ 2.54Å; Y123-K126 WeakPolarHBondContact O-CB 3.33Å; Y123-K126 PolarHBondContact O-N 2.78Å; Y123-K126 VanDerWaalsContact O-N 3.16Å; E124-K126 PolarHBondContact O-N 2.68Å
127	D	68.4	Low	80.8	Confident	110 Å²	110	76.6 Å²	76.6	59%	0.588	39%	0.394	S	S	*	.			trans	-88.3	132.7	167.7	-90.6	-25.5	0	0	0	110.9	E125 N129 N130	E125-D127 PolarHBondContact O-N 2.85Å; D127-N129 PolarHBondContact O-N 3.43Å; D127-N130 HydrophobicContact CB-CB 3.97Å; D127-N130 WeakPolarHBondContact O-CB 3.44Å; D127-N130 PolarHBondContact O-N 3.3Å
128	D	63.8	Low	80.5	Confident	160 Å²	160	83.5 Å²	83.5	86%	0.856	42%	0.424	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.6	-21.7	179	-70	-33.7	0	0	0	113.3
129	N	60.5	Low	80.1	Confident	156 Å²	156	83.7 Å²	83.7	83%	0.834	43%	0.427	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91	-3.9	179.4	-68.2	-32.9	0	0	0	113.9	D127 V131	D127-N129 PolarHBondContact O-N 3.43Å; N129-V131 PolarHBondContact O-N 2.97Å
130	N	61.3	Low	80	Confident	69 Å²	69	83.6 Å²	83.6	37%	0.369	43%	0.426	S	S	.	.			trans	-95.1	95.8	-169.4	-140.1	-9.4	0	0	0	111.5	D127 N132	D127-N130 HydrophobicContact CB-CB 3.97Å; D127-N130 WeakPolarHBondContact O-CB 3.44Å; D127-N130 PolarHBondContact O-N 3.3Å; N130-N132 VanDerWaalsContact C-N 3.29Å; N130-N132 PolarHBondContact O-N 3.49Å
131	V	61.8	Low	79.9	Confident	143 Å²	143	85.6 Å²	85.6	87%	0.867	44%	0.44	S	S	*	.			trans	-71	-22.9	-175.3	-177.2	0	0	0	0	112.7	N129 K133	N129-V131 PolarHBondContact O-N 2.97Å; V131-K133 PolarHBondContact O-N 2.81Å
132	N	77.8	Confident	79.9	Confident	98 Å²	98	90.3 Å²	90.3	52%	0.524	46%	0.461	S	S	.	.			trans	-97.7	89.4	-171	-163.6	1.6	0	0	0	113.6	N130 C134 S135	N130-N132 VanDerWaalsContact C-N 3.29Å; N130-N132 PolarHBondContact O-N 3.49Å; N132-C134 PolarHBondContact O-N 3.19Å; N132-C134 WeakPolarHBondContact OD1-CB 3.5Å; N132-C134 PolarHBondContact OD1-N 2.88Å; N132-S135 WeakPolarHBondContact O-CB 3.41Å; N132-S135 PolarHBondContact O-N 3.42Å
133	K	79.6	Confident	79.9	Confident	152 Å²	152	92.6 Å²	92.6	66%	0.661	47%	0.469	S	S	*	.	H	α-helix	trans	-52.3	-29.5	176.2	-65	-175.7	179.9	-179.9	0	114.1	V131 S135 Q136 V137	V131-K133 PolarHBondContact O-N 2.81Å; K133-S135 VanDerWaalsContact C-N 3.34Å; K133-Q136 PolarHBondContact O-N 2.94Å; K133-V137 WeakPolarHBondContact O-CG2 3.31Å; K133-V137 PolarHBondContact O-N 3.36Å; K133-V137 VanDerWaalsContact O-N 3.17Å
134	C	82.1	Confident	80.3	Confident	92 Å²	92	90.7 Å²	90.7	62%	0.622	46%	0.462	S	S	*	.	H	α-helix	trans	-66.7	-36.2	178.3	-174.2	0	0	0	0	112.1	N132 K138	N132-C134 PolarHBondContact O-N 3.19Å; N132-C134 WeakPolarHBondContact OD1-CB 3.5Å; N132-C134 PolarHBondContact OD1-N 2.88Å; C134-K138 WeakPolarHBondContact O-CB 3.33Å; C134-K138 PolarHBondContact O-N 3.47Å; C134-K138 VanDerWaalsContact O-N 3.11Å
135	S	83.5	Confident	80.8	Confident	44 Å²	44	89.2 Å²	89.2	31%	0.308	46%	0.46	S	S	.	.	H	α-helix	trans	-66.6	-41.2	176.4	-167.4	0	0	0	0	111.4	N132 K133 K138 N139	N132-S135 WeakPolarHBondContact O-CB 3.41Å; N132-S135 PolarHBondContact O-N 3.42Å; K133-S135 VanDerWaalsContact C-N 3.34Å; S135-K138 PolarHBondContact O-N 3.27Å; S135-N139 PolarHBondContact O-N 3.46Å
136	Q	85.4	Confident	81.2	Confident	18 Å²	18	88.6 Å²	88.6	8%	0.084	47%	0.467	C	S	.	.	H	α-helix	trans	-60.4	-47	177.3	-171.4	-177.4	6.8	0	0	111.9	Y122 E125 K133 K138 N139 A140	Y122-Q136 HydrophobicContact CD2-CG 3.9Å; Y122-Q136 HydrophobicContact CE2-CB 4.42Å; Y122-Q136 HydrophobicContact CE2-CG 3.86Å; Y122-Q136 PolarHBondContact O-NE2 3.44Å; E125-Q136 HydrophobicContact CB-CG 4.14Å; E125-Q136 HydrophobicContact CG-CG 4.28Å; K133-Q136 PolarHBondContact O-N 2.94Å; Q136-K138 VanDerWaalsContact C-N 3.33Å; Q136-K138 PolarHBondContact O-N 2.88Å; Q136-N139 PolarHBondContact O-N 2.91Å; Q136-A140 WeakPolarHBondContact O-CB 3.33Å; Q136-A140 PolarHBondContact O-N 2.91Å
137	V	88.4	Confident	82.2	Confident	62 Å²	62	88.3 Å²	88.3	38%	0.376	47%	0.466	S	S	.	.	H	α-helix	trans	-62	-41.5	176.3	174.4	0	0	0	0	111.4	F118 Y122 K133 A140 L141	F118-V137 HydrophobicContact CE2-CG1 4.26Å; F118-V137 HydrophobicContact CZ-CG1 4.28Å; Y122-V137 HydrophobicContact CD2-CG2 4.17Å; Y122-V137 HydrophobicContact CE2-CG2 3.8Å; K133-V137 WeakPolarHBondContact O-CG2 3.31Å; K133-V137 PolarHBondContact O-N 3.36Å; K133-V137 VanDerWaalsContact O-N 3.17Å; V137-A140 PolarHBondContact O-N 2.93Å; V137-L141 WeakPolarHBondContact O-CB 3.44Å; V137-L141 PolarHBondContact O-N 3Å
138	K	88.2	Confident	83.5	Confident	153 Å²	153	85.6 Å²	85.6	67%	0.665	45%	0.453	S	S	*	.	H	α-helix	trans	-63.8	-42.5	178.7	-173.2	-179.6	178.2	-177.8	0	111.8	C134 S135 Q136 K142	C134-K138 WeakPolarHBondContact O-CB 3.33Å; C134-K138 PolarHBondContact O-N 3.47Å; C134-K138 VanDerWaalsContact O-N 3.11Å; S135-K138 PolarHBondContact O-N 3.27Å; Q136-K138 VanDerWaalsContact C-N 3.33Å; Q136-K138 PolarHBondContact O-N 2.88Å; K138-K142 WeakPolarHBondContact O-CB 3.49Å; K138-K142 PolarHBondContact O-N 3.37Å
139	N	87.8	Confident	85	Confident	46 Å²	46	83.3 Å²	83.3	25%	0.246	44%	0.441	C	S	.	.	H	α-helix	trans	-67.2	-45.4	177.3	-73.1	-3.3	0	0	0	111.1	E125 S135 Q136 L141 K142 Y143	E125-N139 HydrophobicContact CG-CB 3.98Å; E125-N139 PolarHBondContact OE1-ND2 2.85Å; S135-N139 PolarHBondContact O-N 3.46Å; Q136-N139 PolarHBondContact O-N 2.91Å; N139-L141 VanDerWaalsContact C-N 3.33Å; N139-L141 PolarHBondContact O-N 3.44Å; N139-K142 WeakPolarHBondContact O-CB 3.29Å; N139-K142 PolarHBondContact O-N 3.48Å; N139-Y143 WeakPolarHBondContact O-CD2 3.34Å; N139-Y143 PolarHBondContact O-N 3.32Å
140	A	90.3	Very high	86.6	Confident	0 Å²	0	79.6 Å²	79.6	0%	0	42%	0.423	C	S	.	.	H	α-helix	trans	-58.9	-43.6	175.4	0	0	0	0	0	112.4	F118 F121 Q136 V137 K142 Y143 T144	F118-A140 HydrophobicContact CD2-CB 4.13Å; F118-A140 HydrophobicContact CE2-CB 4.03Å; F121-A140 HydrophobicContact CB-CB 4.14Å; Q136-A140 WeakPolarHBondContact O-CB 3.33Å; Q136-A140 PolarHBondContact O-N 2.91Å; V137-A140 PolarHBondContact O-N 2.93Å; A140-K142 PolarHBondContact O-N 2.99Å; A140-Y143 PolarHBondContact O-N 3.23Å; A140-T144 WeakPolarHBondContact O-CB 3.5Å; A140-T144 PolarHBondContact O-N 3.43Å; A140-T144 PolarHBondContact O-OG1 2.94Å
141	L	89.9	Confident	88.3	Confident	96 Å²	96	77.1 Å²	77.1	50%	0.503	41%	0.411	S	S	.	.	H	α-helix	trans	-63.1	-43	176.9	-171	70.4	0	0	0	111.3	V137 N139 Y143 T144 V145	V137-L141 WeakPolarHBondContact O-CB 3.44Å; V137-L141 PolarHBondContact O-N 3Å; N139-L141 VanDerWaalsContact C-N 3.33Å; N139-L141 PolarHBondContact O-N 3.44Å; L141-Y143 VanDerWaalsContact C-N 3.3Å; L141-Y143 PolarHBondContact O-N 3.32Å; L141-T144 WeakPolarHBondContact O-CB 3.23Å; L141-T144 PolarHBondContact O-N 2.95Å; L141-T144 VanDerWaalsContact O-N 3.1Å; L141-V145 WeakPolarHBondContact O-CG2 3.22Å; L141-V145 PolarHBondContact O-N 3.24Å; L141-V145 VanDerWaalsContact O-N 3.09Å
142	K	91.8	Very high	89.8	Confident	145 Å²	145	73.8 Å²	73.8	63%	0.63	39%	0.391	S	S	*	.	H	α-helix	trans	-55.2	-44.7	177.2	-178.2	-171.8	173.7	-169.7	0	111.8	K138 N139 A140	K138-K142 WeakPolarHBondContact O-CB 3.49Å; K138-K142 PolarHBondContact O-N 3.37Å; N139-K142 WeakPolarHBondContact O-CB 3.29Å; N139-K142 PolarHBondContact O-N 3.48Å; A140-K142 PolarHBondContact O-N 2.99Å
143	Y	89.3	Confident	90.6	Very high	115 Å²	115	71.3 Å²	71.3	45%	0.451	38%	0.384	S	S	.	.	H	α-helix	trans	-74.5	-29.2	178.2	-64.5	-61.6	0	0	0	113.1	F121 N139 A140 L141 V145	F121-Y143 HydrophobicContact CD1-CD2 4.37Å; F121-Y143 HydrophobicContact CD1-CG 4.26Å; F121-Y143 HydrophobicContact CE1-CG 4.46Å; F121-Y143 HydrophobicContact CG-CG 4.45Å; N139-Y143 WeakPolarHBondContact O-CD2 3.34Å; N139-Y143 PolarHBondContact O-N 3.32Å; A140-Y143 PolarHBondContact O-N 3.23Å; L141-Y143 VanDerWaalsContact C-N 3.3Å; L141-Y143 PolarHBondContact O-N 3.32Å; Y143-V145 VanDerWaalsContact C-N 3.32Å; Y143-V145 PolarHBondContact O-N 3.35Å
144	T	93.9	Very high	91.3	Very high	1 Å²	1	65.6 Å²	65.6	1%	0.006	36%	0.361	C	S	.	.	H	α-helix	trans	-68.1	-29.7	176.5	-54.9	0	0	0	0	112.6	L114 P117 F118 A140 L141 G146 F147 V148	L114-T144 HydrophobicContact CD1-CG2 3.91Å; L114-T144 WeakPolarHBondContact O-CG2 3.37Å; P117-T144 HydrophobicContact CB-CG2 4.4Å; F118-T144 VanDerWaalsContact CA-OG1 3.24Å; F118-T144 WeakPolarHBondContact CA-OG1 3.41Å; F118-T144 HydrophobicContact CB-CG2 4.14Å; F118-T144 PolarHBondContact N-OG1 2.97Å; A140-T144 WeakPolarHBondContact O-CB 3.5Å; A140-T144 PolarHBondContact O-N 3.43Å; A140-T144 PolarHBondContact O-OG1 2.94Å; L141-T144 WeakPolarHBondContact O-CB 3.23Å; L141-T144 PolarHBondContact O-N 2.95Å; L141-T144 VanDerWaalsContact O-N 3.1Å; T144-G146 PolarHBondContact O-N 3.29Å; T144-G146 VanDerWaalsContact O-N 3.11Å; T144-F147 PolarHBondContact O-N 2.93Å; T144-V148 HydrophobicContact CG2-CG2 4.4Å; T144-V148 PolarHBondContact O-N 3.3Å
145	V	94.1	Very high	91.8	Very high	72 Å²	72	64 Å²	64	44%	0.436	35%	0.345	S	S	.	.	H	α-helix	trans	-53.4	-35.5	179.7	169.4	0	0	0	0	112.4	L141 Y143 F147 V148 L149	L141-V145 WeakPolarHBondContact O-CG2 3.22Å; L141-V145 PolarHBondContact O-N 3.24Å; L141-V145 VanDerWaalsContact O-N 3.09Å; Y143-V145 VanDerWaalsContact C-N 3.32Å; Y143-V145 PolarHBondContact O-N 3.35Å; V145-F147 VanDerWaalsContact C-N 3.33Å; V145-F147 PolarHBondContact O-N 3.19Å; V145-V148 PolarHBondContact O-N 2.81Å; V145-L149 HydrophobicContact CG1-CD1 4.1Å; V145-L149 HydrophobicContact CG1-CG 4.21Å; V145-L149 WeakPolarHBondContact O-CG 3.35Å; V145-L149 PolarHBondContact O-N 3.45Å
146	G	93.8	Very high	92.1	Very high	38 Å²	38	66.4 Å²	66.4	39%	0.392	36%	0.355	S	S	.	.	H	α-helix	trans	-58.5	-42.1	176.7	0	0	0	0	0	113.2	T144 L149 V150	T144-G146 PolarHBondContact O-N 3.29Å; T144-G146 VanDerWaalsContact O-N 3.11Å; G146-L149 PolarHBondContact O-N 3.23Å; G146-V150 WeakPolarHBondContact O-CG2 3.46Å; G146-V150 PolarHBondContact O-N 3.5Å
147	F	94.4	Very high	92.4	Very high	84 Å²	84	69.6 Å²	69.6	37%	0.368	37%	0.371	S	S	.	.	H	α-helix	trans	-70.6	-36	178	-69.3	-97.3	0	0	0	112	F113 P117 F121 T144 V145 V150 C151	F113-F147 WeakPolarHBondContact CD1-O 3.48Å; F113-F147 WeakPolarHBondContact O-CB 3.5Å; P117-F147 HydrophobicContact CB-CB 4.4Å; P117-F147 HydrophobicContact CB-CD1 4.27Å; P117-F147 HydrophobicContact CB-CD2 3.84Å; P117-F147 HydrophobicContact CB-CE2 4.17Å; P117-F147 HydrophobicContact CB-CG 3.91Å; P117-F147 HydrophobicContact CG-CB 4.17Å; P117-F147 HydrophobicContact CG-CD1 3.79Å; P117-F147 HydrophobicContact CG-CD2 4.25Å; P117-F147 HydrophobicContact CG-CE1 4.23Å; P117-F147 HydrophobicContact CG-CG 3.8Å; F121-F147 HydrophobicContact CE2-CD2 4.17Å; F121-F147 AromaticContact CE2-CE2 3.62Å; F121-F147 HydrophobicContact CE2-CE2 3.62Å; F121-F147 AromaticContact CZ-CE2 3.92Å; F121-F147 HydrophobicContact CZ-CE2 3.92Å; T144-F147 PolarHBondContact O-N 2.93Å; V145-F147 VanDerWaalsContact C-N 3.33Å; V145-F147 PolarHBondContact O-N 3.19Å; F147-V150 PolarHBondContact O-N 3.11Å; F147-C151 PolarHBondContact O-N 3.49Å
148	V	95.4	Very high	92.3	Very high	53 Å²	53	66.6 Å²	66.6	32%	0.321	35%	0.353	S	S	.	.	H	α-helix	trans	-64	-42	174.3	179.6	0	0	0	0	111	L114 T144 V145 V150 C151 V152	L114-V148 HydrophobicContact CD1-CG2 3.36Å; T144-V148 HydrophobicContact CG2-CG2 4.4Å; T144-V148 PolarHBondContact O-N 3.3Å; V145-V148 PolarHBondContact O-N 2.81Å; V148-V150 VanDerWaalsContact C-N 3.32Å; V148-V150 PolarHBondContact O-N 3.12Å; V148-C151 WeakPolarHBondContact O-CB 3.31Å; V148-C151 PolarHBondContact O-N 2.93Å; V148-C151 VanDerWaalsContact O-N 3.16Å; V148-V152 HydrophobicContact CG1-CG2 4.42Å; V148-V152 WeakPolarHBondContact O-CG2 3.34Å; V148-V152 PolarHBondContact O-N 3.21Å
149	L	95.5	Very high	92.2	Very high	113 Å²	113	60.6 Å²	60.6	59%	0.592	33%	0.332	S	S	*	.	H	α-helix	trans	-61	-41.2	175.9	-71	173	0	0	0	111.8	V145 G146 V152 A153	V145-L149 HydrophobicContact CG1-CD1 4.1Å; V145-L149 HydrophobicContact CG1-CG 4.21Å; V145-L149 WeakPolarHBondContact O-CG 3.35Å; V145-L149 PolarHBondContact O-N 3.45Å; G146-L149 PolarHBondContact O-N 3.23Å; L149-V152 PolarHBondContact O-N 3.5Å; L149-A153 WeakPolarHBondContact O-CB 3.46Å; L149-A153 PolarHBondContact O-N 3.47Å
150	V	95.6	Very high	92	Very high	77 Å²	77	66 Å²	66	47%	0.467	35%	0.354	S	S	.	.	H	α-helix	trans	-62	-44	173.6	174.5	0	0	0	0	111	F113 G146 F147 V148 A153 L154	F113-V150 HydrophobicContact CE1-CB 4.39Å; F113-V150 HydrophobicContact CE1-CG1 3.84Å; G146-V150 WeakPolarHBondContact O-CG2 3.46Å; G146-V150 PolarHBondContact O-N 3.5Å; F147-V150 PolarHBondContact O-N 3.11Å; V148-V150 VanDerWaalsContact C-N 3.32Å; V148-V150 PolarHBondContact O-N 3.12Å; V150-A153 PolarHBondContact O-N 3.3Å; V150-L154 HydrophobicContact CG1-CD1 4.24Å; V150-L154 HydrophobicContact CG1-CG 4.47Å; V150-L154 WeakPolarHBondContact O-CG 3.45Å; V150-L154 PolarHBondContact O-N 3.46Å
151	C	95.3	Very high	91.6	Very high	18 Å²	18	67.6 Å²	67.6	12%	0.122	36%	0.364	C	S	.	.	H	α-helix	trans	-60.6	-46.1	176.8	-171.1	0	0	0	0	112.2	F113 F147 V148 A153 L154 L155	F113-C151 HydrophobicContact CB-CB 3.66Å; F113-C151 HydrophobicContact CD1-CB 4.02Å; F113-C151 HydrophobicContact CD2-CB 3.87Å; F113-C151 HydrophobicContact CG-CB 3.59Å; F147-C151 PolarHBondContact O-N 3.49Å; V148-C151 WeakPolarHBondContact O-CB 3.31Å; V148-C151 PolarHBondContact O-N 2.93Å; V148-C151 VanDerWaalsContact O-N 3.16Å; C151-A153 VanDerWaalsContact C-N 3.32Å; C151-A153 PolarHBondContact O-N 3.05Å; C151-L154 PolarHBondContact O-N 3.14Å; C151-L155 WeakPolarHBondContact O-CG 3.37Å; C151-L155 PolarHBondContact O-N 3.31Å
152	V	94.6	Very high	90.4	Very high	72 Å²	72	67.5 Å²	67.5	44%	0.436	37%	0.369	S	S	.	.	H	α-helix	trans	-60.9	-43.1	176.2	172.3	0	0	0	0	110.6	V148 L149 L155 L156	V148-V152 HydrophobicContact CG1-CG2 4.42Å; V148-V152 WeakPolarHBondContact O-CG2 3.34Å; V148-V152 PolarHBondContact O-N 3.21Å; L149-V152 PolarHBondContact O-N 3.5Å; V152-L155 PolarHBondContact O-N 3.4Å; V152-L156 HydrophobicContact CG1-CD1 3.8Å; V152-L156 HydrophobicContact CG1-CG 4.23Å; V152-L156 WeakPolarHBondContact O-CB 3.47Å; V152-L156 VanDerWaalsContact O-CG 3.24Å; V152-L156 WeakPolarHBondContact O-CG 3.34Å; V152-L156 PolarHBondContact O-N 2.97Å
153	A	94.9	Very high	89.2	Confident	46 Å²	46	64.4 Å²	64.4	38%	0.38	36%	0.359	S	S	.	.	H	α-helix	trans	-61.3	-45.9	176.2	0	0	0	0	0	112	L149 V150 C151 L155 L156 I157	L149-A153 WeakPolarHBondContact O-CB 3.46Å; L149-A153 PolarHBondContact O-N 3.47Å; V150-A153 PolarHBondContact O-N 3.3Å; C151-A153 VanDerWaalsContact C-N 3.32Å; C151-A153 PolarHBondContact O-N 3.05Å; A153-L155 PolarHBondContact O-N 3.25Å; A153-L156 PolarHBondContact O-N 3.42Å; A153-I157 WeakPolarHBondContact O-CB 3.37Å; A153-I157 WeakPolarHBondContact O-CD1 3.45Å; A153-I157 WeakPolarHBondContact O-CG1 3.5Å; A153-I157 PolarHBondContact O-N 2.94Å
154	L	94	Very high	87.4	Confident	32 Å²	32	66.5 Å²	66.5	17%	0.168	37%	0.373	C	S	.	.	H	α-helix	trans	-61.8	-41.9	176.8	-70.6	175.3	0	0	0	112.2	F113 V150 C151 G158 F195	F113-L154 HydrophobicContact CE1-CD1 4.28Å; F113-L154 HydrophobicContact CE2-CD1 4.18Å; F113-L154 HydrophobicContact CZ-CD1 3.55Å; V150-L154 HydrophobicContact CG1-CD1 4.24Å; V150-L154 HydrophobicContact CG1-CG 4.47Å; V150-L154 WeakPolarHBondContact O-CG 3.45Å; V150-L154 PolarHBondContact O-N 3.46Å; C151-L154 PolarHBondContact O-N 3.14Å; L154-G158 PolarHBondContact O-N 3.35Å; L154-F195 HydrophobicContact CD2-CE1 4.06Å; L154-F195 VanDerWaalsContact O-CD1 3.3Å; L154-F195 WeakPolarHBondContact O-CD1 3.29Å
155	L	91.9	Very high	85.3	Confident	58 Å²	58	68.4 Å²	68.4	30%	0.304	39%	0.388	S	S	.	.	H	α-helix	trans	-66.7	-41.9	177.4	-72.1	171.5	0	0	0	112	L109 C151 V152 A153 G158 A159 A192 S196	L109-L155 HydrophobicContact CD1-CD2 4.4Å; C151-L155 WeakPolarHBondContact O-CG 3.37Å; C151-L155 PolarHBondContact O-N 3.31Å; V152-L155 PolarHBondContact O-N 3.4Å; A153-L155 PolarHBondContact O-N 3.25Å; L155-G158 PolarHBondContact O-N 3.47Å; L155-A159 WeakPolarHBondContact O-CB 3.49Å; L155-A159 PolarHBondContact O-N 3.41Å; L155-A192 HydrophobicContact CB-CB 4.49Å; L155-A192 HydrophobicContact CD2-CB 4.01Å; L155-A192 WeakPolarHBondContact O-CB 3.32Å; L155-S196 WeakPolarHBondContact CD2-OG 3.29Å; L155-S196 PolarHBondContact N-OG 3.04Å
156	L	90.7	Very high	83	Confident	96 Å²	96	66.6 Å²	66.6	50%	0.503	38%	0.378	S	S	.	.	H	α-helix	trans	-63.9	-47.5	176	-72.6	172.5	0	0	0	111	V152 A153 G158 A159 F160	V152-L156 HydrophobicContact CG1-CD1 3.8Å; V152-L156 HydrophobicContact CG1-CG 4.23Å; V152-L156 WeakPolarHBondContact O-CB 3.47Å; V152-L156 VanDerWaalsContact O-CG 3.24Å; V152-L156 WeakPolarHBondContact O-CG 3.34Å; V152-L156 PolarHBondContact O-N 2.97Å; A153-L156 PolarHBondContact O-N 3.42Å; L156-G158 VanDerWaalsContact C-N 3.33Å; L156-G158 PolarHBondContact O-N 3.46Å; L156-A159 PolarHBondContact O-N 2.89Å; L156-F160 HydrophobicContact CD2-CE2 4.13Å; L156-F160 WeakPolarHBondContact O-CD2 3.39Å; L156-F160 PolarHBondContact O-N 2.92Å
157	I	90.4	Very high	80.6	Confident	84 Å²	84	71.5 Å²	71.5	43%	0.431	40%	0.403	S	S	.	.	H	α-helix	trans	-56.4	-51.8	175.4	-66.8	163.5	0	0	0	109	A153 A159 F160 V161 F195	A153-I157 WeakPolarHBondContact O-CB 3.37Å; A153-I157 WeakPolarHBondContact O-CD1 3.45Å; A153-I157 WeakPolarHBondContact O-CG1 3.5Å; A153-I157 PolarHBondContact O-N 2.94Å; I157-A159 VanDerWaalsContact C-N 3.27Å; I157-A159 PolarHBondContact O-N 2.93Å; I157-F160 CarbonylContact O-C 3.59Å; I157-F160 PolarHBondContact O-N 3.33Å; I157-V161 HydrophobicContact CG2-CG2 3.51Å; I157-V161 WeakPolarHBondContact O-CG2 3.29Å; I157-V161 PolarHBondContact O-N 3.4Å; I157-F195 HydrophobicContact CB-CD1 4.47Å; I157-F195 HydrophobicContact CB-CE1 3.93Å; I157-F195 HydrophobicContact CB-CZ 4.27Å; I157-F195 HydrophobicContact CG2-CD1 4.28Å; I157-F195 HydrophobicContact CG2-CE1 3.54Å; I157-F195 HydrophobicContact CG2-CE2 3.98Å; I157-F195 HydrophobicContact CG2-CZ 3.37Å
158	G	86.8	Confident	78.5	Confident	0 Å²	0	69.8 Å²	69.8	0%	0	41%	0.409	C	S	.	.	H	α-helix	trans	-61.8	-28.8	179.5	0	0	0	0	0	115.7	L154 L155 L156 S191 A192 F195	L154-G158 PolarHBondContact O-N 3.35Å; L155-G158 PolarHBondContact O-N 3.47Å; L156-G158 VanDerWaalsContact C-N 3.33Å; L156-G158 PolarHBondContact O-N 3.46Å; G158-S191 CarbonylContact O-C 3.43Å; G158-S191 WeakPolarHBondContact O-CB 3.24Å; G158-S191 PolarHBondContact O-OG 3.38Å; G158-A192 PolarHBondContact O-N 3.27Å; G158-F195 VanDerWaalsContact CA-CG 3.47Å
159	A	85.4	Confident	76	Confident	27 Å²	27	75.5 Å²	75.5	22%	0.223	43%	0.432	C	S	.	.	H	α-helix	trans	-72.5	-29.4	175.7	0	0	0	0	0	112.7	L155 L156 I157 A192	L155-A159 WeakPolarHBondContact O-CB 3.49Å; L155-A159 PolarHBondContact O-N 3.41Å; L156-A159 PolarHBondContact O-N 2.89Å; I157-A159 VanDerWaalsContact C-N 3.27Å; I157-A159 PolarHBondContact O-N 2.93Å; A159-A192 HydrophobicContact CB-CB 4.14Å
160	F	83.8	Confident	73.7	Confident	159 Å²	159	78.7 Å²	78.7	70%	0.697	45%	0.45	S	S	*	.	H	α-helix	trans	-114.2	-3.2	-173.3	-64.2	-65.4	0	0	0	114.7	L156 I157 P162	L156-F160 HydrophobicContact CD2-CE2 4.13Å; L156-F160 WeakPolarHBondContact O-CD2 3.39Å; L156-F160 PolarHBondContact O-N 2.92Å; I157-F160 CarbonylContact O-C 3.59Å; I157-F160 PolarHBondContact O-N 3.33Å; F160-P162 VanDerWaalsContact O-CD 3.26Å; F160-P162 WeakPolarHBondContact O-CD 3.4Å
161	V	81.6	Confident	71.5	Confident	34 Å²	34	77.6 Å²	77.6	21%	0.206	45%	0.445	C	S	.	.			trans	-62.5	117.5	175.3	164	0	0	0	0	108.7	I157 L163 F195 F486 F488	I157-V161 HydrophobicContact CG2-CG2 3.51Å; I157-V161 WeakPolarHBondContact O-CG2 3.29Å; I157-V161 PolarHBondContact O-N 3.4Å; V161-L163 PolarHBondContact O-N 2.93Å; V161-F195 HydrophobicContact CG2-CD2 4.17Å; V161-F195 HydrophobicContact CG2-CE2 3.95Å; V161-F486 HydrophobicContact CB-CE1 4.16Å; V161-F486 HydrophobicContact CG1-CD1 4.04Å; V161-F486 HydrophobicContact CG1-CE1 3.69Å; V161-F488 HydrophobicContact CG1-CE1 4.45Å
162	P	66.1	Low	69.8	Low	94 Å²	94	81.6 Å²	81.6	61%	0.61	47%	0.469	S	S	*	.			trans	-67.6	129.6	174.3	27.8	-31.7	0	0	0	108.6	F160 E164	F160-P162 VanDerWaalsContact O-CD 3.26Å; F160-P162 WeakPolarHBondContact O-CD 3.4Å; P162-E164 HydrophobicContact CB-CG 4.2Å; P162-E164 PolarHBondContact O-N 3.39Å
163	L	65.3	Low	67.9	Low	80 Å²	80	81.4 Å²	81.4	42%	0.419	46%	0.463	S	S	.	.			trans	-85.4	19.2	171.7	-67.1	166.6	0	0	0	111.4	V161 A165 K485 F486	V161-L163 PolarHBondContact O-N 2.93Å; L163-A165 PolarHBondContact O-N 3.12Å; L163-A165 VanDerWaalsContact O-N 3.15Å; L163-K485 HydrophobicContact CD1-CG 4.44Å; L163-K485 HydrophobicContact CD2-CG 4.33Å; L163-F486 HydrophobicContact CD2-CD1 3.52Å; L163-F486 HydrophobicContact CD2-CE1 3.53Å; L163-F486 HydrophobicContact CD2-CG 4.42Å; L163-F486 HydrophobicContact CD2-CZ 4.42Å; L163-F486 HydrophobicContact CG-CE1 4.43Å
164	E	52.6	Low	66.2	Low	159 Å²	159	81.2 Å²	81.2	74%	0.743	45%	0.453	S	S	*	.	P	Polyproline II helix	trans	-52	123.6	-174.9	-79.8	176.8	-178.4	0	0	110.4	P162	P162-E164 HydrophobicContact CB-CG 4.2Å; P162-E164 PolarHBondContact O-N 3.39Å
165	A	49.5	Very low	64.7	Low	40 Å²	40	86.1 Å²	86.1	33%	0.331	48%	0.475	S	S	.	.	P	Polyproline II helix	trans	-60.5	138.4	176.4	0	0	0	0	0	109.5	L163 W174	L163-A165 PolarHBondContact O-N 3.12Å; L163-A165 VanDerWaalsContact O-N 3.15Å; A165-W174 HydrophobicContact CB-CZ2 4.08Å
166	P	45.5	Very low	63.1	Low	35 Å²	35	85.7 Å²	85.7	23%	0.227	47%	0.471	C	S	.	.	P	Polyproline II helix	trans	-59.4	136.1	170.9	24.9	-32	0	0	0	109.4	G168 Y339	P166-G168 PolarHBondContact O-N 2.9Å; P166-Y339 HydrophobicContact CG-CD1 4.17Å; P166-Y339 HydrophobicContact CG-CE1 3.71Å
167	P	42.4	Very low	61.7	Low	141 Å²	141	81.7 Å²	81.7	92%	0.916	45%	0.45	S	S	*	.	S	Bend	trans	-74	105.5	-175.2	28.6	-31.6	0	0	0	109.5
168	G	51.7	Low	60.2	Low	47 Å²	47	81.7 Å²	81.7	49%	0.485	45%	0.448	S	S	.	.			trans	136.5	97.3	161.7	0	0	0	0	0	115.2	P166 Y339	P166-G168 PolarHBondContact O-N 2.9Å; G168-Y339 PolarHBondContact O-OH 2.98Å
169	Q	42.3	Very low	58.9	Low	173 Å²	173	86.4 Å²	86.4	81%	0.808	47%	0.467	S	S	*	.				-179.7	147.9	110.5	-97.5	177.5	3.2	0	0	110	S171	Q169-S171 VanDerWaalsContact C-N 3.32Å; Q169-S171 PolarHBondContact O-N 3.42Å
170	N	47.7	Very low	57.5	Low	181 Å²	181	88 Å²	88	97%	0.968	47%	0.471	S	S	*	.			trans	-61	78.1	175.7	-65.4	-28.9	0	0	0	112.3
171	S	49.8	Very low	56.5	Low	53 Å²	53	81.7 Å²	81.7	37%	0.371	44%	0.444	S	S	.	.			trans	-136.2	118.2	176.1	62.9	0	0	0	0	113.1	Q169 Q173 W174	Q169-S171 VanDerWaalsContact C-N 3.32Å; Q169-S171 PolarHBondContact O-N 3.42Å; S171-Q173 PolarHBondContact O-N 2.88Å; S171-Q173 VanDerWaalsContact O-N 3.13Å; S171-W174 PolarHBondContact O-N 3.39Å; S171-W174 VanDerWaalsContact O-N 3.1Å
172	T	58.8	Low	55.5	Low	103 Å²	103	86 Å²	86	63%	0.632	46%	0.462	S	S	*	.	H	α-helix	trans	-56.1	-22.8	171.7	50.6	0	0	0	0	113.3	K176	T172-K176 PolarHBondContact O-N 3.04Å
173	Q	55.3	Low	54.9	Low	67 Å²	67	87.7 Å²	87.7	31%	0.313	46%	0.461	S	S	.	.	H	α-helix	trans	-71.1	-33.2	176.4	-71.8	-174.2	-27.4	0	0	113	S171 K176 V177 D468	S171-Q173 PolarHBondContact O-N 2.88Å; S171-Q173 VanDerWaalsContact O-N 3.13Å; Q173-K176 PolarHBondContact O-N 3.4Å; Q173-V177 WeakPolarHBondContact O-CG2 3.28Å; Q173-V177 PolarHBondContact O-N 3.36Å; Q173-D468 PolarHBondContact NE2-OD1 3.41Å
174	W	58.6	Low	54.2	Low	43 Å²	43	85.2 Å²	85.2	16%	0.163	45%	0.448	C	S	.	.	H	α-helix	trans	-74.6	-35.9	177.1	-177.9	-108.5	0	0	0	111.8	A165 S171 K176 V177 Q178 Y339	A165-W174 HydrophobicContact CB-CZ2 4.08Å; S171-W174 PolarHBondContact O-N 3.39Å; S171-W174 VanDerWaalsContact O-N 3.1Å; W174-K176 PolarHBondContact O-N 3.34Å; W174-V177 HydrophobicContact CE3-CB 4.01Å; W174-V177 HydrophobicContact CE3-CG1 4.07Å; W174-V177 HydrophobicContact CE3-CG2 4.44Å; W174-V177 HydrophobicContact CH2-CG1 4.35Å; W174-V177 HydrophobicContact CZ3-CB 4.22Å; W174-V177 HydrophobicContact CZ3-CG1 3.74Å; W174-V177 PolarHBondContact O-N 2.84Å; W174-V177 VanDerWaalsContact O-N 3.09Å; W174-Q178 WeakPolarHBondContact O-CB 3.22Å; W174-Q178 PolarHBondContact O-N 3.32Å; W174-Y339 HydrophobicContact CD2-CD1 4.09Å; W174-Y339 HydrophobicContact CD2-CE1 4.03Å; W174-Y339 AromaticContact CE3-CD1 3.76Å; W174-Y339 HydrophobicContact CE3-CD1 3.76Å; W174-Y339 HydrophobicContact CE3-CE1 4.18Å; W174-Y339 HydrophobicContact CG-CE1 4.5Å; W174-Y339 AromaticContact CH2-CD1 3.97Å; W174-Y339 HydrophobicContact CH2-CD1 3.97Å; W174-Y339 HydrophobicContact CZ2-CD1 4.28Å; W174-Y339 HydrophobicContact CZ2-CE1 4.45Å; W174-Y339 AromaticContact CZ3-CD1 3.71Å; W174-Y339 HydrophobicContact CZ3-CD1 3.71Å; W174-Y339 HydrophobicContact CZ3-CE1 4.45Å
175	E	62.1	Low	54.1	Low	134 Å²	134	79.2 Å²	79.2	63%	0.626	43%	0.429	S	S	*	.	H	α-helix	trans	-56	-40.8	171.8	-72.5	178.7	162.4	0	0	111.2	V177 Q178 Y179	E175-V177 PolarHBondContact O-N 3.07Å; E175-Q178 PolarHBondContact O-N 2.85Å; E175-Y179 WeakPolarHBondContact O-CB 3.14Å; E175-Y179 PolarHBondContact O-N 2.89Å
176	K	59.3	Low	54.2	Low	50 Å²	50	82.2 Å²	82.2	22%	0.217	45%	0.448	C	S	.	.	H	α-helix	trans	-63	-41.3	174.7	-67.9	-177.2	-177.8	-171.5	0	113.1	T172 Q173 W174 L180 A467 D468 A469	T172-K176 PolarHBondContact O-N 3.04Å; Q173-K176 PolarHBondContact O-N 3.4Å; W174-K176 PolarHBondContact O-N 3.34Å; K176-L180 WeakPolarHBondContact O-CB 3.46Å; K176-L180 VanDerWaalsContact O-CG 3.24Å; K176-L180 WeakPolarHBondContact O-CG 3.1Å; K176-L180 PolarHBondContact O-N 3.17Å; K176-A467 PolarHBondContact NZ-O 3.5Å; K176-A467 VanDerWaalsContact NZ-O 3.08Å; K176-D468 PolarHBondContact NZ-O 3.34Å; K176-A469 PolarHBondContact NZ-O 3.49Å
177	V	60	Low	55	Low	12 Å²	12	88.5 Å²	88.5	7%	0.073	47%	0.467	C	S	.	.	H	α-helix	trans	-68.1	-44	178.1	176.4	0	0	0	0	111	Q173 W174 E175 L180 F181 F344	Q173-V177 WeakPolarHBondContact O-CG2 3.28Å; Q173-V177 PolarHBondContact O-N 3.36Å; W174-V177 HydrophobicContact CE3-CB 4.01Å; W174-V177 HydrophobicContact CE3-CG1 4.07Å; W174-V177 HydrophobicContact CE3-CG2 4.44Å; W174-V177 HydrophobicContact CH2-CG1 4.35Å; W174-V177 HydrophobicContact CZ3-CB 4.22Å; W174-V177 HydrophobicContact CZ3-CG1 3.74Å; W174-V177 PolarHBondContact O-N 2.84Å; W174-V177 VanDerWaalsContact O-N 3.09Å; E175-V177 PolarHBondContact O-N 3.07Å; V177-L180 PolarHBondContact O-N 3.36Å; V177-F181 HydrophobicContact CG1-CD2 3.69Å; V177-F181 HydrophobicContact CG1-CE2 3.37Å; V177-F181 HydrophobicContact CG1-CZ 4.48Å; V177-F181 WeakPolarHBondContact O-CD2 3.41Å; V177-F181 PolarHBondContact O-N 2.89Å; V177-F181 VanDerWaalsContact O-N 3.08Å; V177-F344 HydrophobicContact CG2-CD1 4.15Å; V177-F344 HydrophobicContact CG2-CE1 3.23Å; V177-F344 HydrophobicContact CG2-CZ 3.8Å
178	Q	59.9	Low	56.2	Low	83 Å²	83	88.5 Å²	88.5	39%	0.388	45%	0.454	S	S	.	.	H	α-helix	trans	-61.8	-46.7	176.7	-173.5	176.7	-33.1	0	0	110.3	W174 E175 L180 F181 E182	W174-Q178 WeakPolarHBondContact O-CB 3.22Å; W174-Q178 PolarHBondContact O-N 3.32Å; E175-Q178 PolarHBondContact O-N 2.85Å; Q178-L180 PolarHBondContact O-N 3.21Å; Q178-F181 CarbonylContact O-C 3.58Å; Q178-F181 PolarHBondContact O-N 3.04Å; Q178-F181 VanDerWaalsContact O-N 3.07Å; Q178-E182 PolarHBondContact NE2-OE2 3.45Å; Q178-E182 WeakPolarHBondContact O-CB 3.03Å; Q178-E182 PolarHBondContact O-N 3.08Å
179	Y	59.1	Low	57.3	Low	100 Å²	100	88 Å²	88	39%	0.392	45%	0.45	S	S	.	.	H	α-helix	trans	-55.2	-48.2	173.4	179.4	-99.8	0	0	0	112	E175 F181 E182 E183	E175-Y179 WeakPolarHBondContact O-CB 3.14Å; E175-Y179 PolarHBondContact O-N 2.89Å; Y179-F181 PolarHBondContact O-N 3Å; Y179-E182 PolarHBondContact O-N 2.95Å; Y179-E182 VanDerWaalsContact O-N 3.15Å; Y179-E183 WeakPolarHBondContact CE2-OE2 3.42Å; Y179-E183 WeakPolarHBondContact O-CB 3.32Å; Y179-E183 PolarHBondContact O-N 3.29Å; Y179-E183 PolarHBondContact OH-OE2 3.34Å
180	L	57.2	Low	59.1	Low	60 Å²	60	80.7 Å²	80.7	31%	0.314	42%	0.416	S	S	.	.	H	α-helix	trans	-58.7	-33.5	176.4	-74	170.6	0	0	0	113	K176 V177 Q178 L184 V476 L481	K176-L180 WeakPolarHBondContact O-CB 3.46Å; K176-L180 VanDerWaalsContact O-CG 3.24Å; K176-L180 WeakPolarHBondContact O-CG 3.1Å; K176-L180 PolarHBondContact O-N 3.17Å; V177-L180 PolarHBondContact O-N 3.36Å; Q178-L180 PolarHBondContact O-N 3.21Å; L180-L184 VanDerWaalsContact O-CD1 3.26Å; L180-L184 WeakPolarHBondContact O-CD1 3.5Å; L180-V476 HydrophobicContact CD1-CG2 4.37Å; L180-L481 HydrophobicContact CB-CD2 4.12Å
181	F	61.9	Low	60.8	Low	27 Å²	27	72.7 Å²	72.7	12%	0.118	37%	0.374	C	S	.	.	H	α-helix	trans	-84.6	-28.2	176.7	-69.9	-53.3	0	0	0	113.8	V177 Q178 Y179 G185 L481 H484 K485	V177-F181 HydrophobicContact CG1-CD2 3.69Å; V177-F181 HydrophobicContact CG1-CE2 3.37Å; V177-F181 HydrophobicContact CG1-CZ 4.48Å; V177-F181 WeakPolarHBondContact O-CD2 3.41Å; V177-F181 PolarHBondContact O-N 2.89Å; V177-F181 VanDerWaalsContact O-N 3.08Å; Q178-F181 CarbonylContact O-C 3.58Å; Q178-F181 PolarHBondContact O-N 3.04Å; Q178-F181 VanDerWaalsContact O-N 3.07Å; Y179-F181 PolarHBondContact O-N 3Å; F181-G185 PolarHBondContact O-N 3.13Å; F181-L481 HydrophobicContact CD1-CD2 4.46Å; F181-L481 HydrophobicContact CE1-CD2 4.24Å; F181-H484 WeakPolarHBondContact CZ-O 3.46Å; F181-K485 HydrophobicContact CD1-CB 4.34Å; F181-K485 HydrophobicContact CD1-CG 4.29Å; F181-K485 VanDerWaalsContact CE1-CA 3.45Å; F181-K485 HydrophobicContact CE1-CB 4.26Å
182	E	60.9	Low	62.6	Low	125 Å²	125	70.6 Å²	70.6	58%	0.584	36%	0.36	S	S	*	.	H	α-helix	trans	-79.7	-37.2	-178.5	-164.1	156.8	-173.8	0	0	111.6	Q178 Y179 L184 G185	Q178-E182 PolarHBondContact NE2-OE2 3.45Å; Q178-E182 WeakPolarHBondContact O-CB 3.03Å; Q178-E182 PolarHBondContact O-N 3.08Å; Y179-E182 PolarHBondContact O-N 2.95Å; Y179-E182 VanDerWaalsContact O-N 3.15Å; E182-L184 PolarHBondContact O-N 3.1Å; E182-G185 WeakPolarHBondContact O-CA 3.49Å; E182-G185 PolarHBondContact O-N 2.87Å
183	E	53.7	Low	64.1	Low	128 Å²	128	66.1 Å²	66.1	60%	0.598	33%	0.332	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.1	-32.8	170.9	-162.4	80.7	-164.4	0	0	111.8	Y179	Y179-E183 WeakPolarHBondContact CE2-OE2 3.42Å; Y179-E183 WeakPolarHBondContact O-CB 3.32Å; Y179-E183 PolarHBondContact O-N 3.29Å; Y179-E183 PolarHBondContact OH-OE2 3.34Å
184	L	50.9	Low	65.7	Low	28 Å²	28	62.9 Å²	62.9	15%	0.147	32%	0.317	C	S	.	.	T	Hydrogen-bonded Turn	trans	-87.1	-11.3	174.8	-87.2	79.4	0	0	0	113.1	L180 E182 L190 L481	L180-L184 VanDerWaalsContact O-CD1 3.26Å; L180-L184 WeakPolarHBondContact O-CD1 3.5Å; E182-L184 PolarHBondContact O-N 3.1Å; L184-L190 HydrophobicContact CB-CD2 4.1Å; L184-L190 HydrophobicContact CD2-CD2 4.25Å; L184-L190 WeakPolarHBondContact O-CD2 3.41Å; L184-L481 HydrophobicContact CD1-CD1 3.82Å; L184-L481 HydrophobicContact CD2-CB 3.81Å; L184-L481 HydrophobicContact CD2-CD1 3.91Å; L184-L481 HydrophobicContact CD2-CG 4.45Å
185	G	48.7	Very low	67.3	Low	33 Å²	33	61.8 Å²	61.8	34%	0.34	31%	0.314	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.2	-11.1	-162.2	0	0	0	0	0	116.5	F181 E182 R187	F181-G185 PolarHBondContact O-N 3.13Å; E182-G185 WeakPolarHBondContact O-CA 3.49Å; E182-G185 PolarHBondContact O-N 2.87Å; G185-R187 PolarHBondContact O-N 3.43Å
186	S	53.1	Low	68.8	Low	104 Å²	104	55.4 Å²	55.4	73%	0.727	28%	0.284	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.8	-10.9	-169.7	88.6	0	0	0	0	114.8
187	R	62.3	Low	70.5	Confident	167 Å²	167	53 Å²	53	63%	0.63	27%	0.274	S	S	*	.			trans	-113.7	106.6	177.3	-61.9	-172.9	-176.7	-176.9	2.9	111.7	G185 G189 L190	G185-R187 PolarHBondContact O-N 3.43Å; R187-G189 PolarHBondContact O-N 2.74Å; R187-L190 PolarHBondContact O-N 2.96Å
188	H	67	Low	72	Confident	140 Å²	140	52.5 Å²	52.5	65%	0.648	27%	0.27	S	S	*	.	H	α-helix	trans	-45.8	-33.9	175.4	-65.3	82.2	0	0	0	114.3	L190 S191 A192	H188-L190 VanDerWaalsContact C-N 3.31Å; H188-L190 PolarHBondContact O-N 3.16Å; H188-S191 PolarHBondContact O-N 3.35Å; H188-A192 PolarHBondContact O-N 2.83Å
189	G	75.1	Confident	73.7	Confident	37 Å²	37	49.4 Å²	49.4	38%	0.381	26%	0.258	S	S	.	.	H	α-helix	trans	-63.1	-30	178.5	0	0	0	0	0	114.8	R187 L193	R187-G189 PolarHBondContact O-N 2.74Å; G189-L193 PolarHBondContact O-N 2.79Å
190	L	79.5	Confident	75.4	Confident	19 Å²	19	44.8 Å²	44.8	10%	0.099	24%	0.24	C	C	.	.	H	α-helix	trans	-72.1	-39.7	177.6	-173.9	70.8	0	0	0	111.3	L98 Y102 L184 R187 H188 L193 S194 F482	L98-L190 HydrophobicContact CD1-CD1 4.23Å; Y102-L190 HydrophobicContact CD2-CD1 4.49Å; L184-L190 HydrophobicContact CB-CD2 4.1Å; L184-L190 HydrophobicContact CD2-CD2 4.25Å; L184-L190 WeakPolarHBondContact O-CD2 3.41Å; R187-L190 PolarHBondContact O-N 2.96Å; H188-L190 VanDerWaalsContact C-N 3.31Å; H188-L190 PolarHBondContact O-N 3.16Å; L190-L193 PolarHBondContact O-N 3.18Å; L190-S194 WeakPolarHBondContact O-CB 3.4Å; L190-S194 PolarHBondContact O-N 3.31Å; L190-F482 HydrophobicContact CD1-CD2 3.98Å; L190-F482 HydrophobicContact CD1-CE2 3.74Å
191	S	83.4	Confident	77.2	Confident	13 Å²	13	42 Å²	42	9%	0.091	23%	0.225	C	C	.	.	H	α-helix	trans	-63.4	-44.3	177.6	-166.1	0	0	0	0	111.5	G158 H188 L193 S194 F195	G158-S191 CarbonylContact O-C 3.43Å; G158-S191 WeakPolarHBondContact O-CB 3.24Å; G158-S191 PolarHBondContact O-OG 3.38Å; H188-S191 PolarHBondContact O-N 3.35Å; S191-L193 PolarHBondContact O-N 2.78Å; S191-S194 PolarHBondContact O-N 3.39Å; S191-F195 WeakPolarHBondContact O-CB 3.5Å; S191-F195 PolarHBondContact O-N 3.32Å
192	A	88.6	Confident	78.8	Confident	10 Å²	10	43.1 Å²	43.1	8%	0.083	23%	0.232	C	C	.	.	H	α-helix	trans	-57.8	-48.6	176	0	0	0	0	0	112.8	L155 G158 A159 H188 S196	L155-A192 HydrophobicContact CB-CB 4.49Å; L155-A192 HydrophobicContact CD2-CB 4.01Å; L155-A192 WeakPolarHBondContact O-CB 3.32Å; G158-A192 PolarHBondContact O-N 3.27Å; A159-A192 HydrophobicContact CB-CB 4.14Å; H188-A192 PolarHBondContact O-N 2.83Å; A192-S196 PolarHBondContact O-N 3.41Å; A192-S196 VanDerWaalsContact O-N 3.14Å; A192-S196 PolarHBondContact O-OG 3.16Å; A192-S196 VanDerWaalsContact O-OG 3.05Å
193	L	89.9	Confident	80.4	Confident	8 Å²	8	41.5 Å²	41.5	4%	0.042	23%	0.226	C	C	.	.	H	α-helix	trans	-64.1	-47.9	179.2	-161.4	103.9	0	0	0	111.2	Y102 Y105 S106 L109 G189 L190 S191 F195 S196 I197 F482	Y102-L193 HydrophobicContact CD2-CD1 4.48Å; Y102-L193 HydrophobicContact CD2-CD2 3.94Å; Y102-L193 HydrophobicContact CE2-CB 4.45Å; Y102-L193 HydrophobicContact CE2-CD1 4.2Å; Y102-L193 HydrophobicContact CE2-CD2 4.38Å; Y105-L193 HydrophobicContact CD2-CD2 4.25Å; Y105-L193 HydrophobicContact CG-CD2 4.4Å; S106-L193 VanDerWaalsContact OG-CD1 3.26Å; S106-L193 WeakPolarHBondContact OG-CD1 3.26Å; L109-L193 HydrophobicContact CD1-CD1 3.92Å; L109-L193 HydrophobicContact CD1-CG 4.28Å; G189-L193 PolarHBondContact O-N 2.79Å; L190-L193 PolarHBondContact O-N 3.18Å; S191-L193 PolarHBondContact O-N 2.78Å; L193-F195 VanDerWaalsContact C-N 3.34Å; L193-F195 PolarHBondContact O-N 3.18Å; L193-S196 PolarHBondContact O-N 3.17Å; L193-I197 WeakPolarHBondContact O-CB 3.36Å; L193-I197 VanDerWaalsContact O-CG1 3.31Å; L193-I197 WeakPolarHBondContact O-CG1 3.32Å; L193-I197 PolarHBondContact O-N 3.43Å; L193-F482 HydrophobicContact CB-CE2 4.45Å; L193-F482 HydrophobicContact CB-CZ 4.09Å; L193-F482 HydrophobicContact CD2-CE1 4.34Å; L193-F482 HydrophobicContact CD2-CE2 3.67Å; L193-F482 HydrophobicContact CD2-CZ 3.27Å; L193-F482 HydrophobicContact CG-CZ 3.96Å
194	S	89.7	Confident	82.4	Confident	0 Å²	0	35.4 Å²	35.4	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-57.8	-45.9	179.3	169.9	0	0	0	0	111.3	L190 S191 S196 I197 S198 F482	L190-S194 WeakPolarHBondContact O-CB 3.4Å; L190-S194 PolarHBondContact O-N 3.31Å; S191-S194 PolarHBondContact O-N 3.39Å; S194-S196 PolarHBondContact O-N 2.85Å; S194-I197 PolarHBondContact O-N 2.86Å; S194-S198 WeakPolarHBondContact O-CB 3.26Å; S194-S198 PolarHBondContact O-N 3.33Å; S194-S198 PolarHBondContact O-OG 2.88Å; S194-S198 VanDerWaalsContact O-OG 3.11Å; S194-F482 PolarHBondContact OG-O 3.34Å
195	F	91.6	Very high	84.6	Confident	20 Å²	20	34.6 Å²	34.6	9%	0.088	19%	0.194	C	C	.	.	H	α-helix	trans	-62.4	-43.6	178.6	-177.9	-90.5	0	0	0	112.4	L154 I157 G158 V161 S191 L193 S198 S199 F486 F488 F489	L154-F195 HydrophobicContact CD2-CE1 4.06Å; L154-F195 VanDerWaalsContact O-CD1 3.3Å; L154-F195 WeakPolarHBondContact O-CD1 3.29Å; I157-F195 HydrophobicContact CB-CD1 4.47Å; I157-F195 HydrophobicContact CB-CE1 3.93Å; I157-F195 HydrophobicContact CB-CZ 4.27Å; I157-F195 HydrophobicContact CG2-CD1 4.28Å; I157-F195 HydrophobicContact CG2-CE1 3.54Å; I157-F195 HydrophobicContact CG2-CE2 3.98Å; I157-F195 HydrophobicContact CG2-CZ 3.37Å; G158-F195 VanDerWaalsContact CA-CG 3.47Å; V161-F195 HydrophobicContact CG2-CD2 4.17Å; V161-F195 HydrophobicContact CG2-CE2 3.95Å; S191-F195 WeakPolarHBondContact O-CB 3.5Å; S191-F195 PolarHBondContact O-N 3.32Å; L193-F195 VanDerWaalsContact C-N 3.34Å; L193-F195 PolarHBondContact O-N 3.18Å; F195-S198 PolarHBondContact O-N 3.47Å; F195-S199 WeakPolarHBondContact O-CB 3.25Å; F195-S199 PolarHBondContact O-N 3.23Å; F195-S199 PolarHBondContact O-OG 3.35Å; F195-F486 HydrophobicContact CB-CD2 4.48Å; F195-F486 HydrophobicContact CB-CE2 3.64Å; F195-F486 HydrophobicContact CB-CZ 3.73Å; F195-F486 HydrophobicContact CD2-CD1 4.48Å; F195-F486 HydrophobicContact CD2-CD2 4.48Å; F195-F486 HydrophobicContact CD2-CE1 4.17Å; F195-F486 HydrophobicContact CD2-CE2 4.2Å; F195-F486 HydrophobicContact CD2-CZ 4.04Å; F195-F486 HydrophobicContact CG-CE2 4.44Å; F195-F486 HydrophobicContact CG-CZ 4.38Å; F195-F488 HydrophobicContact CD2-CZ 4.26Å; F195-F488 HydrophobicContact CE2-CE2 4.33Å; F195-F488 AromaticContact CE2-CZ 3.86Å; F195-F488 HydrophobicContact CE2-CZ 3.86Å; F195-F489 AromaticContact CD2-CE2 3.77Å; F195-F489 HydrophobicContact CD2-CE2 3.77Å; F195-F489 HydrophobicContact CD2-CZ 4.35Å; F195-F489 AromaticContact CE2-CE2 3.8Å; F195-F489 HydrophobicContact CE2-CE2 3.8Å; F195-F489 HydrophobicContact CE2-CZ 4.03Å; F195-F489 HydrophobicContact CG-CE2 4.46Å; F195-F489 HydrophobicContact CZ-CE2 4.5Å; F195-F489 HydrophobicContact CZ-CZ 4.31Å
196	S	93.8	Very high	86.8	Confident	0 Å²	0	38 Å²	38	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-66.7	-40.2	-179	-63.8	0	0	0	0	111.3	L155 A192 L193 S194 S199 L200	L155-S196 WeakPolarHBondContact CD2-OG 3.29Å; L155-S196 PolarHBondContact N-OG 3.04Å; A192-S196 PolarHBondContact O-N 3.41Å; A192-S196 VanDerWaalsContact O-N 3.14Å; A192-S196 PolarHBondContact O-OG 3.16Å; A192-S196 VanDerWaalsContact O-OG 3.05Å; L193-S196 PolarHBondContact O-N 3.17Å; S194-S196 PolarHBondContact O-N 2.85Å; S196-S199 WeakPolarHBondContact O-CB 3.5Å; S196-S199 PolarHBondContact O-N 3.44Å; S196-L200 WeakPolarHBondContact O-CG 3.32Å; S196-L200 PolarHBondContact O-N 3.12Å
197	I	93.8	Very high	88.8	Confident	0 Å²	0	33.6 Å²	33.6	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-67.7	-43.2	174.5	-66.8	-62.2	0	0	0	111.5	Y105 I108 L109 L193 S194 S199 L200 T201 L422 F482 L483	Y105-I197 HydrophobicContact CD1-CD1 3.92Å; Y105-I197 HydrophobicContact CD1-CG1 4.2Å; Y105-I197 HydrophobicContact CD1-CG2 4.24Å; Y105-I197 HydrophobicContact CD2-CG1 4.46Å; Y105-I197 HydrophobicContact CE1-CG2 4.23Å; Y105-I197 HydrophobicContact CG-CD1 4.01Å; Y105-I197 HydrophobicContact CG-CG1 3.94Å; I108-I197 HydrophobicContact CG2-CD1 4.37Å; L109-I197 HydrophobicContact CD1-CD1 4.44Å; L109-I197 HydrophobicContact CD2-CD1 4.19Å; L109-I197 HydrophobicContact CG-CD1 3.96Å; L193-I197 WeakPolarHBondContact O-CB 3.36Å; L193-I197 VanDerWaalsContact O-CG1 3.31Å; L193-I197 WeakPolarHBondContact O-CG1 3.32Å; L193-I197 PolarHBondContact O-N 3.43Å; S194-I197 PolarHBondContact O-N 2.86Å; I197-S199 PolarHBondContact O-N 3.35Å; I197-L200 PolarHBondContact O-N 3.35Å; I197-L200 VanDerWaalsContact O-N 3.07Å; I197-T201 HydrophobicContact CG2-CG2 4.46Å; I197-T201 WeakPolarHBondContact O-CG2 3.25Å; I197-T201 PolarHBondContact O-N 2.9Å; I197-T201 PolarHBondContact O-OG1 3.16Å; I197-L422 HydrophobicContact CG2-CD1 4.1Å; I197-L422 HydrophobicContact CG2-CD2 4.25Å; I197-L422 HydrophobicContact CG2-CG 4.47Å; I197-F482 HydrophobicContact CB-CE1 3.84Å; I197-F482 HydrophobicContact CG1-CE1 4Å; I197-F482 HydrophobicContact CG1-CZ 4.35Å; I197-F482 HydrophobicContact CG2-CE1 3.94Å; I197-L483 HydrophobicContact CG2-CD2 4.19Å
198	S	93	Very high	90.4	Very high	0 Å²	0	25.7 Å²	25.7	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-63.6	-30.1	174.8	-63.5	0	0	0	0	112.6	S194 F195 T201 L202 Y493	S194-S198 WeakPolarHBondContact O-CB 3.26Å; S194-S198 PolarHBondContact O-N 3.33Å; S194-S198 PolarHBondContact O-OG 2.88Å; S194-S198 VanDerWaalsContact O-OG 3.11Å; F195-S198 PolarHBondContact O-N 3.47Å; S198-T201 VanDerWaalsContact C-OG1 3.28Å; S198-T201 VanDerWaalsContact CA-OG1 3.22Å; S198-T201 WeakPolarHBondContact CA-OG1 3.45Å; S198-T201 PolarHBondContact O-OG1 3.48Å; S198-L202 PolarHBondContact O-N 3.14Å; S198-L202 VanDerWaalsContact O-N 3.16Å; S198-Y493 PolarHBondContact O-OH 2.95Å
199	S	94.5	Very high	91.8	Very high	18 Å²	18	20.5 Å²	20.5	13%	0.126	12%	0.121	C	C	.	.	H	α-helix	trans	-68.6	-41	171	-57.7	0	0	0	0	111.7	F195 S196 I197 L202 I203 F489	F195-S199 WeakPolarHBondContact O-CB 3.25Å; F195-S199 PolarHBondContact O-N 3.23Å; F195-S199 PolarHBondContact O-OG 3.35Å; S196-S199 WeakPolarHBondContact O-CB 3.5Å; S196-S199 PolarHBondContact O-N 3.44Å; I197-S199 PolarHBondContact O-N 3.35Å; S199-L202 WeakPolarHBondContact O-CB 3.38Å; S199-L202 PolarHBondContact O-N 3.42Å; S199-I203 PolarHBondContact O-N 3.44Å; S199-F489 WeakPolarHBondContact OG-CZ 3.5Å
200	L	95.1	Very high	92.6	Very high	4 Å²	4	21.7 Å²	21.7	2%	0.021	12%	0.121	C	C	.	.	H	α-helix	trans	-68.4	-39.2	175.5	-71.6	-176.8	0	0	0	112.8	I108 L109 V112 F113 S196 I197 L202 I203 G204 L419 L422	I108-L200 HydrophobicContact CG2-CD1 4.42Å; L109-L200 HydrophobicContact CD2-CD1 3.7Å; V112-L200 HydrophobicContact CB-CD1 4.47Å; V112-L200 HydrophobicContact CG1-CD1 4.4Å; V112-L200 HydrophobicContact CG1-CD2 4.03Å; V112-L200 HydrophobicContact CG2-CD1 4.41Å; F113-L200 HydrophobicContact CE2-CD1 4.09Å; F113-L200 HydrophobicContact CE2-CD2 3.92Å; F113-L200 HydrophobicContact CE2-CG 4.23Å; F113-L200 HydrophobicContact CZ-CD2 3.78Å; F113-L200 HydrophobicContact CZ-CG 4.47Å; S196-L200 WeakPolarHBondContact O-CG 3.32Å; S196-L200 PolarHBondContact O-N 3.12Å; I197-L200 PolarHBondContact O-N 3.35Å; I197-L200 VanDerWaalsContact O-N 3.07Å; L200-L202 PolarHBondContact O-N 3.11Å; L200-I203 HydrophobicContact CD2-CD1 4.37Å; L200-I203 PolarHBondContact O-N 2.99Å; L200-G204 PolarHBondContact O-N 2.9Å; L200-L419 HydrophobicContact CB-CD2 3.98Å; L200-L419 HydrophobicContact CD2-CD2 4.02Å; L200-L419 HydrophobicContact CG-CD2 4.44Å; L200-L422 HydrophobicContact CB-CD2 3.71Å
201	T	94.3	Very high	93.4	Very high	1 Å²	1	21.4 Å²	21.4	1%	0.006	12%	0.118	C	C	.	.	H	α-helix	trans	-65.2	-26.7	174.6	53	0	0	0	0	112	I197 S198 G204 M205 L422 H423 L483 Y493	I197-T201 HydrophobicContact CG2-CG2 4.46Å; I197-T201 WeakPolarHBondContact O-CG2 3.25Å; I197-T201 PolarHBondContact O-N 2.9Å; I197-T201 PolarHBondContact O-OG1 3.16Å; S198-T201 VanDerWaalsContact C-OG1 3.28Å; S198-T201 VanDerWaalsContact CA-OG1 3.22Å; S198-T201 WeakPolarHBondContact CA-OG1 3.45Å; S198-T201 PolarHBondContact O-OG1 3.48Å; T201-G204 CarbonylContact O-C 3.55Å; T201-G204 PolarHBondContact O-N 2.65Å; T201-M205 PolarHBondContact O-N 3.24Å; T201-L422 HydrophobicContact CG2-CB 4.4Å; T201-L422 HydrophobicContact CG2-CD2 3.8Å; T201-L422 HydrophobicContact CG2-CG 3.55Å; T201-H423 PolarHBondContact O-ND1 3.47Å; T201-L483 HydrophobicContact CG2-CD2 4.33Å; T201-Y493 PolarHBondContact OG1-OH 3.01Å
202	L	95.3	Very high	94	Very high	50 Å²	50	20.8 Å²	20.8	26%	0.262	11%	0.114	S	C	.	.	H	α-helix	trans	-65.5	-42.4	172	-176.9	71.4	0	0	0	111.4	S198 S199 L200 G204 M205 L206 F489 I492 Y493	S198-L202 PolarHBondContact O-N 3.14Å; S198-L202 VanDerWaalsContact O-N 3.16Å; S199-L202 WeakPolarHBondContact O-CB 3.38Å; S199-L202 PolarHBondContact O-N 3.42Å; L200-L202 PolarHBondContact O-N 3.11Å; L202-G204 VanDerWaalsContact C-N 3.32Å; L202-M205 HydrophobicContact CD1-CE 3.74Å; L202-M205 WeakPolarHBondContact O-CB 3.42Å; L202-M205 PolarHBondContact O-N 3.13Å; L202-L206 PolarHBondContact O-N 2.83Å; L202-F489 HydrophobicContact CD2-CE1 4.38Å; L202-I492 HydrophobicContact CD1-CB 4.23Å; L202-I492 HydrophobicContact CD1-CD1 4.44Å; L202-I492 HydrophobicContact CD1-CG2 3.36Å; L202-Y493 HydrophobicContact CB-CE1 4.32Å; L202-Y493 HydrophobicContact CD1-CE1 4.27Å
203	I	95.3	Very high	94.3	Very high	91 Å²	91	20.3 Å²	20.3	47%	0.467	11%	0.11	S	C	.	.	H	α-helix	trans	-65.2	-41.3	172.3	-56.1	172.5	0	0	0	109.7	S199 L200 M205 L206 A207 L419	S199-I203 PolarHBondContact O-N 3.44Å; L200-I203 HydrophobicContact CD2-CD1 4.37Å; L200-I203 PolarHBondContact O-N 2.99Å; I203-M205 VanDerWaalsContact C-N 3.3Å; I203-M205 PolarHBondContact O-N 3.04Å; I203-L206 WeakPolarHBondContact O-CB 3.35Å; I203-L206 PolarHBondContact O-N 3.38Å; I203-A207 PolarHBondContact O-N 2.97Å; I203-A207 VanDerWaalsContact O-N 3.17Å; I203-L419 HydrophobicContact CB-CD1 4.42Å; I203-L419 HydrophobicContact CG2-CD1 3.82Å
204	G	95.9	Very high	94.5	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-58.3	-38	173.9	0	0	0	0	0	113.5	L200 T201 L202 L206 A207 V208 L419	L200-G204 PolarHBondContact O-N 2.9Å; T201-G204 CarbonylContact O-C 3.55Å; T201-G204 PolarHBondContact O-N 2.65Å; L202-G204 VanDerWaalsContact C-N 3.32Å; G204-L206 PolarHBondContact O-N 3.09Å; G204-A207 CarbonylContact O-C 3.51Å; G204-A207 WeakPolarHBondContact O-CB 3.38Å; G204-A207 PolarHBondContact O-N 3.3Å; G204-V208 WeakPolarHBondContact O-CG2 3.18Å; G204-V208 PolarHBondContact O-N 3.29Å; G204-L419 WeakPolarHBondContact CA-O 3.34Å
205	M	96.1	Very high	94.8	Very high	12 Å²	12	21.6 Å²	21.6	6%	0.059	12%	0.115	C	C	.	.	H	α-helix	trans	-59.4	-46.3	175.8	-175.9	-171.8	71.8	0	0	111.2	T201 L202 I203 A207 V208 I209 H423 I492 Y493	T201-M205 PolarHBondContact O-N 3.24Å; L202-M205 HydrophobicContact CD1-CE 3.74Å; L202-M205 WeakPolarHBondContact O-CB 3.42Å; L202-M205 PolarHBondContact O-N 3.13Å; I203-M205 VanDerWaalsContact C-N 3.3Å; I203-M205 PolarHBondContact O-N 3.04Å; M205-A207 VanDerWaalsContact C-N 3.31Å; M205-A207 PolarHBondContact O-N 2.96Å; M205-V208 PolarHBondContact O-N 2.67Å; M205-I209 HydrophobicContact CG-CD1 3.9Å; M205-I209 VanDerWaalsContact O-CG1 3.29Å; M205-I209 WeakPolarHBondContact O-CG1 3.29Å; M205-I209 PolarHBondContact O-N 3.35Å; M205-H423 VanDerWaalsContact CB-CE1 3.46Å; M205-H423 WeakPolarHBondContact CB-CE1 3.37Å; M205-I492 HydrophobicContact CE-CG2 3.89Å; M205-I492 HydrophobicContact SD-CG2 4.44Å; M205-Y493 HydrophobicContact SD-CD1 3.81Å
206	L	95.4	Very high	94.9	Very high	104 Å²	104	20.7 Å²	20.7	55%	0.545	11%	0.111	S	C	.	.	H	α-helix	trans	-59.4	-45.1	176	-61.6	177.3	0	0	0	110.7	L202 I203 G204 V208 I209 T210	L202-L206 PolarHBondContact O-N 2.83Å; I203-L206 WeakPolarHBondContact O-CB 3.35Å; I203-L206 PolarHBondContact O-N 3.38Å; G204-L206 PolarHBondContact O-N 3.09Å; L206-V208 VanDerWaalsContact C-N 3.32Å; L206-V208 PolarHBondContact O-N 3Å; L206-I209 PolarHBondContact O-N 2.9Å; L206-T210 WeakPolarHBondContact O-CG2 3.4Å; L206-T210 PolarHBondContact O-N 2.97Å; L206-T210 PolarHBondContact O-OG1 3.44Å; L206-T210 VanDerWaalsContact O-OG1 3.11Å
207	A	94.9	Very high	94.9	Very high	12 Å²	12	20.9 Å²	20.9	10%	0.099	11%	0.112	C	C	.	.	H	α-helix	trans	-62.7	-36.5	176.8	0	0	0	0	0	112.8	I203 G204 M205 T210 Y211 I416 I420	I203-A207 PolarHBondContact O-N 2.97Å; I203-A207 VanDerWaalsContact O-N 3.17Å; G204-A207 CarbonylContact O-C 3.51Å; G204-A207 WeakPolarHBondContact O-CB 3.38Å; G204-A207 PolarHBondContact O-N 3.3Å; M205-A207 VanDerWaalsContact C-N 3.31Å; M205-A207 PolarHBondContact O-N 2.96Å; A207-T210 PolarHBondContact O-OG1 3Å; A207-Y211 HydrophobicContact CB-CD2 4.34Å; A207-Y211 VanDerWaalsContact O-CB 3.29Å; A207-Y211 WeakPolarHBondContact O-CB 3.46Å; A207-Y211 WeakPolarHBondContact O-CD2 3.32Å; A207-Y211 PolarHBondContact O-N 3.34Å; A207-I416 HydrophobicContact CB-CG2 4.21Å; A207-I420 HydrophobicContact CB-CD1 4.14Å; A207-I420 HydrophobicContact CB-CG1 3.71Å
208	V	96.1	Very high	94.9	Very high	1 Å²	1	21 Å²	21	1%	0.006	11%	0.112	C	C	.	.	I	π-helix	trans	-69.9	-42.7	177.3	167.2	0	0	0	0	111.5	G204 M205 L206 T210 T212 A213 I420 H423 M427 F500	G204-V208 WeakPolarHBondContact O-CG2 3.18Å; G204-V208 PolarHBondContact O-N 3.29Å; M205-V208 PolarHBondContact O-N 2.67Å; L206-V208 VanDerWaalsContact C-N 3.32Å; L206-V208 PolarHBondContact O-N 3Å; V208-T210 VanDerWaalsContact C-N 3.34Å; V208-T210 PolarHBondContact O-N 3.25Å; V208-T212 WeakPolarHBondContact CA-OG1 3.41Å; V208-T212 HydrophobicContact CG1-CG2 4.39Å; V208-T212 WeakPolarHBondContact O-CA 3.35Å; V208-T212 WeakPolarHBondContact O-CB 3.37Å; V208-T212 PolarHBondContact O-N 2.86Å; V208-A213 PolarHBondContact O-N 3.35Å; V208-I420 HydrophobicContact CG2-CB 4.14Å; V208-I420 HydrophobicContact CG2-CG1 3.96Å; V208-I420 HydrophobicContact CG2-CG2 3.92Å; V208-H423 HydrophobicContact CG2-CB 4.29Å; V208-M427 HydrophobicContact CG1-CE 4.37Å; V208-M427 HydrophobicContact CG1-SD 4.22Å; V208-F500 HydrophobicContact CG1-CD2 3.7Å; V208-F500 HydrophobicContact CG1-CE2 3.55Å
209	I	95.9	Very high	94.8	Very high	31 Å²	31	22.8 Å²	22.8	16%	0.159	12%	0.121	C	C	.	.	I	π-helix	trans	-61.9	-42.5	175.2	-66.2	163.9	0	0	0	110.8	M205 L206 A213 A499 F500 A503	M205-I209 HydrophobicContact CG-CD1 3.9Å; M205-I209 VanDerWaalsContact O-CG1 3.29Å; M205-I209 WeakPolarHBondContact O-CG1 3.29Å; M205-I209 PolarHBondContact O-N 3.35Å; L206-I209 PolarHBondContact O-N 2.9Å; I209-A213 VanDerWaalsContact O-CB 3.28Å; I209-A213 WeakPolarHBondContact O-CB 3.39Å; I209-A499 HydrophobicContact CD1-CB 3.97Å; I209-F500 HydrophobicContact CG1-CB 4.11Å; I209-A503 HydrophobicContact CG2-CB 3.97Å
210	T	93.6	Very high	94.7	Very high	62 Å²	62	22 Å²	22	38%	0.38	12%	0.115	S	C	.	.	I	π-helix	trans	-77.2	-49.1	-178	56.4	0	0	0	0	112.9	L206 A207 V208 Y214	L206-T210 WeakPolarHBondContact O-CG2 3.4Å; L206-T210 PolarHBondContact O-N 2.97Å; L206-T210 PolarHBondContact O-OG1 3.44Å; L206-T210 VanDerWaalsContact O-OG1 3.11Å; A207-T210 PolarHBondContact O-OG1 3Å; V208-T210 VanDerWaalsContact C-N 3.34Å; V208-T210 PolarHBondContact O-N 3.25Å; T210-Y214 WeakPolarHBondContact O-CB 3.33Å
211	Y	95.1	Very high	94.5	Very high	13 Å²	13	22.7 Å²	22.7	5%	0.051	12%	0.119	C	C	.	.	I	π-helix	trans	-98.8	-44.1	-168.6	-64.8	-60.7	0	0	0	113.2	A207 G215 G384 I385 M388 G389 I390 W391 I416	A207-Y211 HydrophobicContact CB-CD2 4.34Å; A207-Y211 VanDerWaalsContact O-CB 3.29Å; A207-Y211 WeakPolarHBondContact O-CB 3.46Å; A207-Y211 WeakPolarHBondContact O-CD2 3.32Å; A207-Y211 PolarHBondContact O-N 3.34Å; Y211-G215 WeakPolarHBondContact O-CA 3.31Å; Y211-G215 PolarHBondContact O-N 3.49Å; Y211-G384 WeakPolarHBondContact O-CA 3.39Å; Y211-I385 HydrophobicContact CD1-CB 4.18Å; Y211-I385 HydrophobicContact CD1-CG1 3.57Å; Y211-I385 HydrophobicContact CD2-CG1 3.94Å; Y211-I385 HydrophobicContact CE1-CB 4.45Å; Y211-I385 HydrophobicContact CE1-CG1 4.06Å; Y211-I385 HydrophobicContact CE2-CG1 4.4Å; Y211-I385 HydrophobicContact CG-CD1 4.46Å; Y211-I385 HydrophobicContact CG-CG1 3.49Å; Y211-I385 VanDerWaalsContact CG-CG1 3.49Å; Y211-M388 HydrophobicContact CD1-CE 4.32Å; Y211-M388 HydrophobicContact CE1-CB 4.41Å; Y211-M388 HydrophobicContact CE1-CE 3.72Å; Y211-M388 HydrophobicContact CE1-SD 4.42Å; Y211-G389 VanDerWaalsContact CE1-O 3.27Å; Y211-G389 WeakPolarHBondContact CE1-O 3.37Å; Y211-G389 PolarHBondContact OH-O 2.87Å; Y211-I390 WeakPolarHBondContact OH-CA 3.47Å; Y211-W391 PolarHBondContact OH-N 3.07Å; Y211-W391 VanDerWaalsContact OH-N 3.08Å; Y211-I416 HydrophobicContact CD2-CG2 4.19Å; Y211-I416 HydrophobicContact CE2-CD1 4.45Å; Y211-I416 HydrophobicContact CE2-CG2 4.34Å
212	T	96.1	Very high	94.3	Very high	0 Å²	0	24.3 Å²	24.3	0%	0	13%	0.128	C	C	.	.	I	π-helix	trans	-72.7	-47	-177.2	-44.7	0	0	0	0	110.7	V208 Y214 G215 M216 F377 S381 F500	V208-T212 WeakPolarHBondContact CA-OG1 3.41Å; V208-T212 HydrophobicContact CG1-CG2 4.39Å; V208-T212 WeakPolarHBondContact O-CA 3.35Å; V208-T212 WeakPolarHBondContact O-CB 3.37Å; V208-T212 PolarHBondContact O-N 2.86Å; T212-Y214 PolarHBondContact O-N 2.89Å; T212-G215 CarbonylContact O-C 3.53Å; T212-G215 WeakPolarHBondContact O-CA 3.43Å; T212-G215 PolarHBondContact O-N 3.17Å; T212-G215 VanDerWaalsContact O-N 3.08Å; T212-M216 HydrophobicContact CG2-CG 4.41Å; T212-M216 VanDerWaalsContact O-CG 3.31Å; T212-M216 WeakPolarHBondContact O-CG 3.38Å; T212-M216 PolarHBondContact O-N 3.41Å; T212-F377 HydrophobicContact CG2-CD1 3.62Å; T212-F377 HydrophobicContact CG2-CE1 4.39Å; T212-S381 WeakPolarHBondContact CB-OG 3.47Å; T212-S381 WeakPolarHBondContact CG2-OG 3.17Å; T212-S381 PolarHBondContact OG1-OG 3.42Å; T212-F500 HydrophobicContact CG2-CE2 4.36Å
213	A	95.7	Very high	94	Very high	0 Å²	0	23.9 Å²	23.9	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-60	-45.6	179.4	0	0	0	0	0	112.2	V208 I209 F500 A503 F504	V208-A213 PolarHBondContact O-N 3.35Å; I209-A213 VanDerWaalsContact O-CB 3.28Å; I209-A213 WeakPolarHBondContact O-CB 3.39Å; A213-F500 HydrophobicContact CB-CD2 3.8Å; A213-F500 HydrophobicContact CB-CE2 3.75Å; A213-F500 HydrophobicContact CB-CG 4.48Å; A213-F500 HydrophobicContact CB-CZ 4.39Å; A213-A503 HydrophobicContact CB-CB 3.86Å; A213-F504 HydrophobicContact CB-CB 4.24Å
214	Y	94.3	Very high	93.7	Very high	35 Å²	35	21.9 Å²	21.9	14%	0.137	12%	0.116	C	C	.	.	H	α-helix	trans	-65.5	-40.7	172.6	180	-114.2	0	0	0	111.9	T210 T212 M216 S217 V218 N387 M388	T210-Y214 WeakPolarHBondContact O-CB 3.33Å; T212-Y214 PolarHBondContact O-N 2.89Å; Y214-M216 PolarHBondContact O-N 2.87Å; Y214-S217 PolarHBondContact O-N 3.24Å; Y214-S217 PolarHBondContact O-OG 3.45Å; Y214-V218 HydrophobicContact CD1-CG1 4.21Å; Y214-V218 HydrophobicContact CE1-CB 4.15Å; Y214-V218 HydrophobicContact CE1-CG1 3.99Å; Y214-V218 HydrophobicContact CE1-CG2 4.25Å; Y214-V218 HydrophobicContact CE2-CB 4.2Å; Y214-V218 HydrophobicContact CE2-CG2 4.37Å; Y214-V218 WeakPolarHBondContact O-CB 3.39Å; Y214-V218 VanDerWaalsContact O-CG1 3.31Å; Y214-V218 WeakPolarHBondContact O-CG1 3.38Å; Y214-V218 PolarHBondContact O-N 2.9Å; Y214-N387 HydrophobicContact CE1-CB 3.93Å; Y214-M388 HydrophobicContact CE1-CB 4.46Å
215	G	94.9	Very high	93.3	Very high	0 Å²	0	24.3 Å²	24.3	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-56	-46.8	175.7	0	0	0	0	0	114.2	Y211 T212 S217 V218 M219 T380	Y211-G215 WeakPolarHBondContact O-CA 3.31Å; Y211-G215 PolarHBondContact O-N 3.49Å; T212-G215 CarbonylContact O-C 3.53Å; T212-G215 WeakPolarHBondContact O-CA 3.43Å; T212-G215 PolarHBondContact O-N 3.17Å; T212-G215 VanDerWaalsContact O-N 3.08Å; G215-S217 PolarHBondContact O-N 3.11Å; G215-V218 PolarHBondContact O-N 2.92Å; G215-M219 WeakPolarHBondContact O-CB 3.21Å; G215-M219 PolarHBondContact O-N 3.04Å; G215-T380 WeakPolarHBondContact CA-O 3.43Å
216	M	94.3	Very high	92.7	Very high	1 Å²	1	24.1 Å²	24.1	1%	0.005	13%	0.127	C	C	.	.	H	α-helix	trans	-62.4	-28.9	179.4	-70.9	-167.7	-34	0	0	112.6	T212 Y214 P220 A316 Y376 F377 T380 F500 F504	T212-M216 HydrophobicContact CG2-CG 4.41Å; T212-M216 VanDerWaalsContact O-CG 3.31Å; T212-M216 WeakPolarHBondContact O-CG 3.38Å; T212-M216 PolarHBondContact O-N 3.41Å; Y214-M216 PolarHBondContact O-N 2.87Å; M216-P220 WeakPolarHBondContact O-CD 3.47Å; M216-P220 WeakPolarHBondContact O-CG 3.5Å; M216-A316 HydrophobicContact CB-CB 4.45Å; M216-Y376 HydrophobicContact CG-CE1 4.02Å; M216-Y376 HydrophobicContact SD-CE1 3.98Å; M216-F377 HydrophobicContact SD-CD1 4.38Å; M216-F377 HydrophobicContact SD-CE1 3.84Å; M216-T380 HydrophobicContact CB-CG2 4.48Å; M216-T380 HydrophobicContact CG-CG2 3.99Å; M216-F500 HydrophobicContact CE-CE1 3.58Å; M216-F500 HydrophobicContact CE-CE2 4.42Å; M216-F500 HydrophobicContact CE-CZ 3.35Å; M216-F500 HydrophobicContact SD-CE1 4.4Å; M216-F500 HydrophobicContact SD-CZ 3.81Å; M216-F504 HydrophobicContact CB-CD2 4Å; M216-F504 HydrophobicContact CB-CE2 4.01Å; M216-F504 HydrophobicContact CE-CB 4.28Å; M216-F504 HydrophobicContact CE-CD2 3.5Å; M216-F504 VanDerWaalsContact CE-CD2 3.5Å; M216-F504 HydrophobicContact CE-CE2 4Å; M216-F504 HydrophobicContact CE-CG 3.95Å
217	S	94.2	Very high	92	Very high	3 Å²	3	22.9 Å²	22.9	2%	0.021	12%	0.124	C	C	.	.	H	α-helix	trans	-88.5	-46.4	176.8	56.9	0	0	0	0	112.2	Y214 G215 P220 L221 G507	Y214-S217 PolarHBondContact O-N 3.24Å; Y214-S217 PolarHBondContact O-OG 3.45Å; G215-S217 PolarHBondContact O-N 3.11Å; S217-P220 WeakPolarHBondContact O-CD 3.41Å; S217-P220 WeakPolarHBondContact O-CG 3.33Å; S217-L221 WeakPolarHBondContact O-CB 3.44Å; S217-L221 WeakPolarHBondContact O-CD1 3.49Å; S217-L221 WeakPolarHBondContact O-CG 3.48Å; S217-L221 PolarHBondContact O-N 3.05Å; S217-G507 PolarHBondContact OG-O 3.46Å
218	V	92.3	Very high	91.3	Very high	2 Å²	2	26.5 Å²	26.5	1%	0.012	14%	0.135	C	C	.	.	H	α-helix	trans	-73.1	-34.9	-173.8	80.2	0	0	0	0	113.1	Y214 G215 N222 N387	Y214-V218 HydrophobicContact CD1-CG1 4.21Å; Y214-V218 HydrophobicContact CE1-CB 4.15Å; Y214-V218 HydrophobicContact CE1-CG1 3.99Å; Y214-V218 HydrophobicContact CE1-CG2 4.25Å; Y214-V218 HydrophobicContact CE2-CB 4.2Å; Y214-V218 HydrophobicContact CE2-CG2 4.37Å; Y214-V218 WeakPolarHBondContact O-CB 3.39Å; Y214-V218 VanDerWaalsContact O-CG1 3.31Å; Y214-V218 WeakPolarHBondContact O-CG1 3.38Å; Y214-V218 PolarHBondContact O-N 2.9Å; G215-V218 PolarHBondContact O-N 2.92Å; V218-N222 VanDerWaalsContact O-CB 3.26Å; V218-N222 WeakPolarHBondContact O-CB 3.03Å; V218-N222 PolarHBondContact O-N 3.14Å; V218-N222 PolarHBondContact O-ND2 3.44Å; V218-N387 VanDerWaalsContact CG1-ND2 3.27Å; V218-N387 WeakPolarHBondContact CG1-ND2 3.36Å
219	M	92.1	Very high	90.5	Very high	38 Å²	38	29.8 Å²	29.8	19%	0.187	16%	0.158	C	C	.	.	H	α-helix	trans	-61.5	-56.4	-178.3	177.3	176.7	170.2	0	0	112.7	G215 N222 L223 F312 T380 A383	G215-M219 WeakPolarHBondContact O-CB 3.21Å; G215-M219 PolarHBondContact O-N 3.04Å; M219-N222 PolarHBondContact O-N 3.06Å; M219-L223 HydrophobicContact CG-CD1 4.44Å; M219-L223 PolarHBondContact O-N 3.44Å; M219-F312 HydrophobicContact CE-CD2 4.28Å; M219-F312 HydrophobicContact CE-CE2 3.87Å; M219-F312 HydrophobicContact CE-CZ 4.27Å; M219-T380 HydrophobicContact SD-CG2 3.96Å; M219-A383 HydrophobicContact CB-CB 3.76Å; M219-A383 HydrophobicContact CG-CB 4.13Å; M219-A383 HydrophobicContact SD-CB 4.16Å
220	P	92.7	Very high	89.8	Confident	1 Å²	1	29.6 Å²	29.6	1%	0.006	16%	0.158	C	C	.	.	H	α-helix	trans	-65.1	-39	178.2	22.1	-31.8	0	0	0	112.8	M216 S217 N222 L223 I224 G309 F312 I313	M216-P220 WeakPolarHBondContact O-CD 3.47Å; M216-P220 WeakPolarHBondContact O-CG 3.5Å; S217-P220 WeakPolarHBondContact O-CD 3.41Å; S217-P220 WeakPolarHBondContact O-CG 3.33Å; P220-N222 VanDerWaalsContact C-N 3.33Å; P220-N222 PolarHBondContact O-N 3.42Å; P220-L223 WeakPolarHBondContact O-CB 3.42Å; P220-L223 PolarHBondContact O-N 2.8Å; P220-L223 VanDerWaalsContact O-N 3.09Å; P220-I224 WeakPolarHBondContact O-CG1 3.46Å; P220-I224 PolarHBondContact O-N 2.71Å; P220-G309 VanDerWaalsContact CB-O 3.22Å; P220-G309 WeakPolarHBondContact CB-O 3.34Å; P220-F312 HydrophobicContact CB-CB 3.94Å; P220-I313 HydrophobicContact CB-CD1 4.22Å; P220-I313 HydrophobicContact CB-CG1 3.48Å; P220-I313 VanDerWaalsContact CB-CG1 3.48Å; P220-I313 HydrophobicContact CG-CG1 3.73Å
221	L	90.9	Very high	89.2	Confident	19 Å²	19	29.5 Å²	29.5	10%	0.099	16%	0.164	C	C	.	.	H	α-helix	trans	-66.5	-35.6	-179.8	-71.6	171.6	0	0	0	112	S217 L223 I224 K225 I313	S217-L221 WeakPolarHBondContact O-CB 3.44Å; S217-L221 WeakPolarHBondContact O-CD1 3.49Å; S217-L221 WeakPolarHBondContact O-CG 3.48Å; S217-L221 PolarHBondContact O-N 3.05Å; L221-L223 VanDerWaalsContact C-N 3.34Å; L221-I224 PolarHBondContact O-N 3.11Å; L221-K225 VanDerWaalsContact O-CB 3.28Å; L221-K225 WeakPolarHBondContact O-CB 3.25Å; L221-K225 WeakPolarHBondContact O-CG 3.16Å; L221-K225 PolarHBondContact O-N 3.46Å; L221-I313 HydrophobicContact CD2-CD1 4Å; L221-I313 HydrophobicContact CG-CD1 4.43Å
222	N	89.1	Confident	88.7	Confident	36 Å²	36	35 Å²	35	19%	0.193	19%	0.185	C	C	.	.	H	α-helix	trans	-64.9	-36.8	171.1	-75.4	-29.9	0	0	0	112.3	V218 M219 P220 G226 N387	V218-N222 VanDerWaalsContact O-CB 3.26Å; V218-N222 WeakPolarHBondContact O-CB 3.03Å; V218-N222 PolarHBondContact O-N 3.14Å; V218-N222 PolarHBondContact O-ND2 3.44Å; M219-N222 PolarHBondContact O-N 3.06Å; P220-N222 VanDerWaalsContact C-N 3.33Å; P220-N222 PolarHBondContact O-N 3.42Å; N222-G226 WeakPolarHBondContact O-CA 3.15Å; N222-G226 PolarHBondContact O-N 2.96Å; N222-N387 PolarHBondContact ND2-ND2 2.97Å
223	L	88.7	Confident	88.1	Confident	41 Å²	41	35 Å²	35	22%	0.215	19%	0.185	C	C	.	.	H	α-helix	trans	-64.6	-41.3	175.6	-75.7	162.6	0	0	0	111.4	M219 P220 L221 K305 L308 F312	M219-L223 HydrophobicContact CG-CD1 4.44Å; M219-L223 PolarHBondContact O-N 3.44Å; P220-L223 WeakPolarHBondContact O-CB 3.42Å; P220-L223 PolarHBondContact O-N 2.8Å; P220-L223 VanDerWaalsContact O-N 3.09Å; L221-L223 VanDerWaalsContact C-N 3.34Å; L223-K305 HydrophobicContact CD2-CB 4.44Å; L223-L308 HydrophobicContact CD1-CD2 4.3Å; L223-F312 HydrophobicContact CD1-CD2 3.99Å; L223-F312 HydrophobicContact CD1-CE2 4.29Å
224	I	89.3	Confident	87.6	Confident	49 Å²	49	39.8 Å²	39.8	25%	0.251	20%	0.203	S	C	.	.	H	α-helix	trans	-71.8	-51.6	179	-63.8	167.2	0	0	0	111.5	P220 L221 R302 V310 I313	P220-I224 WeakPolarHBondContact O-CG1 3.46Å; P220-I224 PolarHBondContact O-N 2.71Å; L221-I224 PolarHBondContact O-N 3.11Å; I224-R302 PolarHBondContact O-NH2 2.94Å; I224-V310 HydrophobicContact CD1-CG2 4.16Å; I224-I313 HydrophobicContact CD1-CD1 3.54Å; I224-I313 HydrophobicContact CD1-CG1 4.46Å
225	K	88.2	Confident	87.4	Confident	51 Å²	51	42.8 Å²	42.8	22%	0.222	22%	0.221	C	C	.	.	H	α-helix	trans	-69.2	-37.2	-177.6	-72.5	-179.8	173.8	-175.8	0	112.4	L221 R302 S511 C512 R514 K516	L221-K225 VanDerWaalsContact O-CB 3.28Å; L221-K225 WeakPolarHBondContact O-CB 3.25Å; L221-K225 WeakPolarHBondContact O-CG 3.16Å; L221-K225 PolarHBondContact O-N 3.46Å; K225-R302 PolarHBondContact O-NH2 2.88Å; K225-S511 PolarHBondContact NZ-O 2.95Å; K225-C512 VanDerWaalsContact NZ-C 3.34Å; K225-C512 PolarHBondContact NZ-O 2.91Å; K225-R514 PolarHBondContact NZ-O 2.86Å; K225-K516 HydrophobicContact CB-CG 4.45Å
226	G	82.5	Confident	87	Confident	7 Å²	7	45.4 Å²	45.4	7%	0.072	23%	0.234	C	C	.	.			trans	68.8	-166.5	-177.2	0	0	0	0	0	115.5	N222 R302	N222-G226 WeakPolarHBondContact O-CA 3.15Å; N222-G226 PolarHBondContact O-N 2.96Å; G226-R302 VanDerWaalsContact N-NH2 3.15Å
227	T	81.4	Confident	86.8	Confident	78 Å²	78	45.5 Å²	45.5	48%	0.479	23%	0.234	S	C	.	.	B	Isolated β-bridge	trans	-91.3	159.9	173.8	54.6	0	0	0	0	110.5	K517	T227-K517 CarbonylContact C-O 3.59Å; T227-K517 VanDerWaalsContact CA-O 3.29Å; T227-K517 WeakPolarHBondContact CA-O 3.32Å
228	R	80.3	Confident	86.7	Confident	88 Å²	88	48.4 Å²	48.4	33%	0.332	25%	0.252	S	S	.	.	P	Polyproline II helix	trans	-65.3	164.7	166.3	-60.9	179.8	84.5	172.1	-1.5	110	E233 E236 K516 K517 V519	R228-E233 HydrophobicContact CB-CG 3.99Å; R228-E233 WeakPolarHBondContact CB-OE1 3.04Å; R228-E233 WeakPolarHBondContact CD-OE1 3.37Å; R228-E236 IonicContact CZ-OE2 3.91Å; R228-E236 IonicContact NH1-OE1 2.54Å; R228-E236 IonicContact NH1-OE2 2.68Å; R228-E236 IonicContact NH2-OE2 2.76Å; R228-E236 PolarHBondContact NH2-OE2 3.33Å; R228-K516 HydrophobicContact CG-CB 3.79Å; R228-K517 PolarHBondContact N-O 3.12Å; R228-V519 WeakPolarHBondContact O-CG2 3.21Å
229	S	79.2	Confident	86.7	Confident	71 Å²	71	53.9 Å²	53.9	50%	0.497	28%	0.277	S	S	.	.	P	Polyproline II helix	trans	-72.8	133.6	176.9	176.3	0	0	0	0	109.8	A231 Y232 E233	S229-A231 VanDerWaalsContact C-N 3.28Å; S229-A231 PolarHBondContact O-N 3.47Å; S229-A231 PolarHBondContact OG-N 3.42Å; S229-Y232 PolarHBondContact O-N 3.34Å; S229-Y232 VanDerWaalsContact O-N 3.16Å; S229-E233 PolarHBondContact O-N 3.42Å
230	V	80.6	Confident	86.7	Confident	27 Å²	27	54.7 Å²	54.7	16%	0.164	28%	0.282	C	S	.	.	H	α-helix	trans	-56.4	-44.7	175	178.7	0	0	0	0	110.6	Y232 E233 R234 L286 E290 V519	V230-Y232 VanDerWaalsContact C-N 3.28Å; V230-Y232 PolarHBondContact O-N 2.98Å; V230-E233 PolarHBondContact O-N 2.97Å; V230-R234 WeakPolarHBondContact O-CB 3.29Å; V230-R234 PolarHBondContact O-N 3.31Å; V230-L286 HydrophobicContact CG1-CD2 4.23Å; V230-E290 HydrophobicContact CG1-CB 4.13Å; V230-V519 HydrophobicContact CG2-CB 4.2Å; V230-V519 HydrophobicContact CG2-CG1 3.84Å; V230-V519 HydrophobicContact CG2-CG2 3.84Å
231	A	80.9	Confident	86.8	Confident	60 Å²	60	56 Å²	56	50%	0.496	29%	0.289	S	S	.	.	H	α-helix	trans	-62.2	-35.6	179.9	0	0	0	0	0	112.7	S229 L235	S229-A231 VanDerWaalsContact C-N 3.28Å; S229-A231 PolarHBondContact O-N 3.47Å; S229-A231 PolarHBondContact OG-N 3.42Å; A231-L235 PolarHBondContact O-N 2.79Å; A231-L235 VanDerWaalsContact O-N 3.13Å
232	Y	84.6	Confident	86.9	Confident	127 Å²	127	59.4 Å²	59.4	50%	0.498	31%	0.307	S	S	.	.	H	α-helix	trans	-72.8	-45.3	177.4	-175.6	-85.4	0	0	0	111.3	S229 V230 R234 L235 E236	S229-Y232 PolarHBondContact O-N 3.34Å; S229-Y232 VanDerWaalsContact O-N 3.16Å; V230-Y232 VanDerWaalsContact C-N 3.28Å; V230-Y232 PolarHBondContact O-N 2.98Å; Y232-R234 PolarHBondContact O-N 2.89Å; Y232-L235 PolarHBondContact O-N 3.47Å; Y232-E236 WeakPolarHBondContact O-CB 3.4Å; Y232-E236 PolarHBondContact O-N 3.46Å
233	E	84.3	Confident	87.2	Confident	2 Å²	2	63.1 Å²	63.1	1%	0.009	32%	0.324	C	S	.	.	H	α-helix	trans	-64.6	-29.9	177.1	-68.5	-163.2	165.7	0	0	112.5	R228 S229 V230 N237 L286 S518 V519	R228-E233 HydrophobicContact CB-CG 3.99Å; R228-E233 WeakPolarHBondContact CB-OE1 3.04Å; R228-E233 WeakPolarHBondContact CD-OE1 3.37Å; S229-E233 PolarHBondContact O-N 3.42Å; V230-E233 PolarHBondContact O-N 2.97Å; E233-N237 WeakPolarHBondContact O-CB 3.26Å; E233-N237 PolarHBondContact O-N 3.37Å; E233-L286 HydrophobicContact CB-CD1 4.41Å; E233-L286 HydrophobicContact CB-CD2 3.91Å; E233-S518 VanDerWaalsContact CD-OG 3.23Å; E233-S518 WeakPolarHBondContact OE1-CA 3.39Å; E233-S518 WeakPolarHBondContact OE1-CB 3.34Å; E233-S518 PolarHBondContact OE1-OG 2.53Å; E233-S518 VanDerWaalsContact OE1-OG 3.09Å; E233-S518 PolarHBondContact OE2-OG 2.84Å; E233-V519 PolarHBondContact OE2-N 3.43Å
234	R	85.1	Confident	87.5	Confident	99 Å²	99	61.9 Å²	61.9	37%	0.374	32%	0.318	S	S	.	.	H	α-helix	trans	-67.4	-46.6	173	-170.8	-179	-176	-153	-8.9	111.7	V230 Y232 N237 T238 L286 D287 E290	V230-R234 WeakPolarHBondContact O-CB 3.29Å; V230-R234 PolarHBondContact O-N 3.31Å; Y232-R234 PolarHBondContact O-N 2.89Å; R234-N237 PolarHBondContact O-N 3.33Å; R234-T238 PolarHBondContact O-N 3.26Å; R234-T238 PolarHBondContact O-OG1 2.69Å; R234-L286 HydrophobicContact CB-CD1 4.3Å; R234-D287 IonicContact CZ-OD1 3.44Å; R234-D287 IonicContact NE-OD1 3.69Å; R234-D287 PolarHBondContact NE-OD1 2.67Å; R234-D287 IonicContact NH2-OD1 2.81Å; R234-D287 PolarHBondContact NH2-OD1 2.74Å; R234-D287 VanDerWaalsContact NH2-OD1 3.13Å; R234-E290 IonicContact CZ-OE2 3.16Å; R234-E290 IonicContact NE-OE2 3.78Å; R234-E290 IonicContact NH1-OE2 3.8Å; R234-E290 PolarHBondContact NH1-OE2 2.87Å
235	L	89.1	Confident	87.7	Confident	99 Å²	99	63.2 Å²	63.2	52%	0.518	32%	0.323	S	S	.	.	H	α-helix	trans	-59.4	-48.4	176	-171.9	70.4	0	0	0	111	A231 Y232 N237 T238 E239	A231-L235 PolarHBondContact O-N 2.79Å; A231-L235 VanDerWaalsContact O-N 3.13Å; Y232-L235 PolarHBondContact O-N 3.47Å; L235-N237 VanDerWaalsContact C-N 3.34Å; L235-N237 PolarHBondContact O-N 2.96Å; L235-T238 PolarHBondContact O-N 3.29Å; L235-E239 WeakPolarHBondContact O-CG 3.26Å; L235-E239 PolarHBondContact O-N 3.08Å
236	E	88.2	Confident	88.1	Confident	55 Å²	55	66 Å²	66	26%	0.257	34%	0.337	S	S	.	.	H	α-helix	trans	-57.7	-44.6	175.8	-173	174.9	-171.7	0	0	111.2	R228 Y232 T238 E239 D240	R228-E236 IonicContact CZ-OE2 3.91Å; R228-E236 IonicContact NH1-OE1 2.54Å; R228-E236 IonicContact NH1-OE2 2.68Å; R228-E236 IonicContact NH2-OE2 2.76Å; R228-E236 PolarHBondContact NH2-OE2 3.33Å; Y232-E236 WeakPolarHBondContact O-CB 3.4Å; Y232-E236 PolarHBondContact O-N 3.46Å; E236-T238 PolarHBondContact O-N 3.11Å; E236-E239 PolarHBondContact O-N 3.48Å; E236-D240 VanDerWaalsContact O-CG 3.29Å; E236-D240 PolarHBondContact O-N 3.34Å
237	N	89.7	Confident	88.6	Confident	2 Å²	2	69.3 Å²	69.3	1%	0.011	35%	0.35	C	S	.	.	H	α-helix	trans	-68.5	-32.6	178.4	-168.5	83.2	0	0	0	113.1	E233 R234 L235 I241 L279 R282 G283 L286	E233-N237 WeakPolarHBondContact O-CB 3.26Å; E233-N237 PolarHBondContact O-N 3.37Å; R234-N237 PolarHBondContact O-N 3.33Å; L235-N237 VanDerWaalsContact C-N 3.34Å; L235-N237 PolarHBondContact O-N 2.96Å; N237-I241 WeakPolarHBondContact O-CD1 3.43Å; N237-I241 WeakPolarHBondContact O-CG1 3.26Å; N237-I241 PolarHBondContact O-N 2.62Å; N237-I241 VanDerWaalsContact O-N 3.08Å; N237-L279 PolarHBondContact ND2-O 2.87Å; N237-L279 WeakPolarHBondContact OD1-CD2 3.09Å; N237-L279 PolarHBondContact OD1-O 2.7Å; N237-R282 WeakPolarHBondContact OD1-CD 3.42Å; N237-G283 PolarHBondContact ND2-N 3.49Å; N237-L286 HydrophobicContact CB-CD1 3.9Å
238	T	91.5	Very high	89.1	Confident	64 Å²	64	66.1 Å²	66.1	39%	0.393	33%	0.33	S	S	.	.	H	α-helix	trans	-69.3	-43.9	173.7	-58.4	0	0	0	0	110.8	R234 L235 E236 D240 I241 D242	R234-T238 PolarHBondContact O-N 3.26Å; R234-T238 PolarHBondContact O-OG1 2.69Å; L235-T238 PolarHBondContact O-N 3.29Å; E236-T238 PolarHBondContact O-N 3.11Å; T238-D240 VanDerWaalsContact C-N 3.33Å; T238-D240 PolarHBondContact O-N 3.15Å; T238-I241 PolarHBondContact O-N 2.6Å; T238-D242 PolarHBondContact O-N 3.39Å
239	E	93.3	Very high	89.6	Confident	117 Å²	117	68 Å²	68	55%	0.547	34%	0.342	S	S	.	.	H	α-helix	trans	-59.2	-43.4	174.8	-71.6	174.2	-177.3	0	0	111.4	L235 E236 I241 D242 E243	L235-E239 WeakPolarHBondContact O-CG 3.26Å; L235-E239 PolarHBondContact O-N 3.08Å; E236-E239 PolarHBondContact O-N 3.48Å; E239-I241 PolarHBondContact O-N 3.12Å; E239-D242 PolarHBondContact O-N 3.43Å; E239-E243 PolarHBondContact O-N 3.38Å
240	D	92	Very high	90.2	Very high	55 Å²	55	68 Å²	68	29%	0.294	34%	0.337	S	S	.	.	H	α-helix	trans	-62.6	-39.6	175.5	-73.1	-20.9	0	0	0	112.3	E236 T238 V244 L279	E236-D240 VanDerWaalsContact O-CG 3.29Å; E236-D240 PolarHBondContact O-N 3.34Å; T238-D240 VanDerWaalsContact C-N 3.33Å; T238-D240 PolarHBondContact O-N 3.15Å; D240-V244 VanDerWaalsContact O-CG2 3.29Å; D240-V244 WeakPolarHBondContact O-CG2 3.31Å; D240-V244 PolarHBondContact O-N 2.66Å; D240-L279 HydrophobicContact CB-CD1 3.93Å; D240-L279 HydrophobicContact CB-CD2 3.98Å
241	I	93.1	Very high	90.6	Very high	28 Å²	28	67.7 Å²	67.7	14%	0.144	33%	0.334	C	S	.	.	H	α-helix	trans	-63.1	-49.3	176.2	-73.2	166.5	0	0	0	110	N237 T238 E239 E243 V244 E245 L279	N237-I241 WeakPolarHBondContact O-CD1 3.43Å; N237-I241 WeakPolarHBondContact O-CG1 3.26Å; N237-I241 PolarHBondContact O-N 2.62Å; N237-I241 VanDerWaalsContact O-N 3.08Å; T238-I241 PolarHBondContact O-N 2.6Å; E239-I241 PolarHBondContact O-N 3.12Å; I241-E243 VanDerWaalsContact C-N 3.3Å; I241-E243 PolarHBondContact O-N 2.87Å; I241-V244 PolarHBondContact O-N 3.49Å; I241-E245 HydrophobicContact CG2-CG 4.27Å; I241-E245 WeakPolarHBondContact O-CB 3.4Å; I241-E245 WeakPolarHBondContact O-CG 3.39Å; I241-E245 PolarHBondContact O-N 3.08Å; I241-L279 HydrophobicContact CD1-CB 4.27Å; I241-L279 HydrophobicContact CG1-CB 3.65Å; I241-L279 HydrophobicContact CG1-CD1 4.28Å
242	D	94.4	Very high	90.8	Very high	92 Å²	92	69.8 Å²	69.8	49%	0.492	33%	0.332	S	S	.	.	H	α-helix	trans	-60.8	-40.2	-179.3	-69	-16.4	0	0	0	111.2	T238 E239 H246	T238-D242 PolarHBondContact O-N 3.39Å; E239-D242 PolarHBondContact O-N 3.43Å; D242-H246 VanDerWaalsContact O-CB 3.31Å; D242-H246 WeakPolarHBondContact O-CB 3.34Å; D242-H246 PolarHBondContact O-N 2.8Å
243	E	95.3	Very high	91	Very high	114 Å²	114	66.3 Å²	66.3	53%	0.533	33%	0.326	S	S	.	.	H	α-helix	trans	-63.7	-47	175.9	-171.1	-177.3	166.5	0	0	111.7	E239 I241 H246 Q247	E239-E243 PolarHBondContact O-N 3.38Å; I241-E243 VanDerWaalsContact C-N 3.3Å; I241-E243 PolarHBondContact O-N 2.87Å; E243-H246 PolarHBondContact O-N 3.23Å; E243-Q247 WeakPolarHBondContact O-CG 3.31Å; E243-Q247 PolarHBondContact O-N 3.04Å; E243-Q247 PolarHBondContact OE1-NE2 3.38Å
244	V	94.1	Very high	91	Very high	15 Å²	15	73 Å²	73	9%	0.091	36%	0.355	C	S	.	.	H	α-helix	trans	-66.3	-41.4	-180	172.2	0	0	0	0	111.2	D240 I241 Q247 I248 L272 L276 L279	D240-V244 VanDerWaalsContact O-CG2 3.29Å; D240-V244 WeakPolarHBondContact O-CG2 3.31Å; D240-V244 PolarHBondContact O-N 2.66Å; I241-V244 PolarHBondContact O-N 3.49Å; V244-Q247 PolarHBondContact O-N 3.4Å; V244-I248 HydrophobicContact CG1-CD1 3.91Å; V244-I248 HydrophobicContact CG1-CG1 4.45Å; V244-I248 VanDerWaalsContact O-CG1 3.3Å; V244-I248 WeakPolarHBondContact O-CG1 3.27Å; V244-I248 PolarHBondContact O-N 2.96Å; V244-L272 HydrophobicContact CG1-CB 4.36Å; V244-L272 HydrophobicContact CG1-CD2 4.14Å; V244-L276 HydrophobicContact CG1-CB 3.98Å; V244-L276 HydrophobicContact CG1-CD1 4.39Å; V244-L279 HydrophobicContact CG2-CD1 3.98Å
245	E	94.9	Very high	90.4	Very high	76 Å²	76	70 Å²	70	36%	0.355	35%	0.349	S	S	.	.	H	α-helix	trans	-60.2	-45.8	174.7	-76.7	-172.4	171.9	0	0	111.1	I241 Q247 I248 E249 L276	I241-E245 HydrophobicContact CG2-CG 4.27Å; I241-E245 WeakPolarHBondContact O-CB 3.4Å; I241-E245 WeakPolarHBondContact O-CG 3.39Å; I241-E245 PolarHBondContact O-N 3.08Å; E245-Q247 VanDerWaalsContact C-N 3.33Å; E245-Q247 PolarHBondContact O-N 3.02Å; E245-I248 WeakPolarHBondContact O-CB 3.41Å; E245-I248 PolarHBondContact O-N 2.98Å; E245-I248 VanDerWaalsContact O-N 3.15Å; E245-E249 WeakPolarHBondContact O-CG 3.29Å; E245-E249 PolarHBondContact O-N 3.42Å; E245-L276 HydrophobicContact CG-CD1 3.47Å; E245-L276 VanDerWaalsContact CG-CD1 3.47Å
246	H	94.8	Very high	89.5	Confident	111 Å²	111	73.9 Å²	73.9	51%	0.514	36%	0.362	S	S	.	.	H	α-helix	trans	-62.5	-37	175.9	-178.2	-109.2	0	0	0	112.6	D242 E243 E249 N250	D242-H246 VanDerWaalsContact O-CB 3.31Å; D242-H246 WeakPolarHBondContact O-CB 3.34Å; D242-H246 PolarHBondContact O-N 2.8Å; E243-H246 PolarHBondContact O-N 3.23Å; H246-E249 PolarHBondContact O-N 3.39Å; H246-N250 PolarHBondContact CE1-ND2 3.01Å; H246-N250 PolarHBondContact ND1-ND2 3.11Å; H246-N250 PolarHBondContact NE2-ND2 2.9Å; H246-N250 WeakPolarHBondContact O-CB 3.45Å; H246-N250 VanDerWaalsContact O-CG 3.31Å; H246-N250 PolarHBondContact O-N 2.96Å; H246-N250 PolarHBondContact O-ND2 2.81Å
247	Q	93.1	Very high	88.9	Confident	75 Å²	75	77.9 Å²	77.9	35%	0.35	39%	0.385	S	S	.	.	H	α-helix	trans	-66	-40.9	173.4	-71.7	-179.4	12.7	0	0	112.2	E243 V244 E245 N250 L251 L272	E243-Q247 WeakPolarHBondContact O-CG 3.31Å; E243-Q247 PolarHBondContact O-N 3.04Å; E243-Q247 PolarHBondContact OE1-NE2 3.38Å; V244-Q247 PolarHBondContact O-N 3.4Å; E245-Q247 VanDerWaalsContact C-N 3.33Å; E245-Q247 PolarHBondContact O-N 3.02Å; Q247-N250 PolarHBondContact O-N 3.49Å; Q247-L251 PolarHBondContact O-N 3.16Å; Q247-L272 HydrophobicContact CB-CD1 4.19Å; Q247-L272 HydrophobicContact CB-CD2 4.48Å; Q247-L272 VanDerWaalsContact OE1-CD2 3.29Å
248	I	92.7	Very high	88	Confident	11 Å²	11	81.1 Å²	81.1	6%	0.056	42%	0.419	C	S	.	.	H	α-helix	trans	-63.4	-45.2	175.5	-69.6	167.2	0	0	0	110.3	V244 E245 L251 K252 L272 E273 L276	V244-I248 HydrophobicContact CG1-CD1 3.91Å; V244-I248 HydrophobicContact CG1-CG1 4.45Å; V244-I248 VanDerWaalsContact O-CG1 3.3Å; V244-I248 WeakPolarHBondContact O-CG1 3.27Å; V244-I248 PolarHBondContact O-N 2.96Å; E245-I248 WeakPolarHBondContact O-CB 3.41Å; E245-I248 PolarHBondContact O-N 2.98Å; E245-I248 VanDerWaalsContact O-N 3.15Å; I248-L251 PolarHBondContact O-N 3.16Å; I248-K252 HydrophobicContact CG2-CD 3.88Å; I248-K252 HydrophobicContact CG2-CG 4.39Å; I248-K252 WeakPolarHBondContact O-CB 3.5Å; I248-K252 WeakPolarHBondContact O-CG 3.33Å; I248-K252 PolarHBondContact O-N 3.41Å; I248-L272 HydrophobicContact CD1-CB 4.15Å; I248-L272 HydrophobicContact CG1-CB 3.78Å; I248-L272 HydrophobicContact CG1-CD1 4.38Å; I248-E273 HydrophobicContact CD1-CG 4.32Å; I248-L276 HydrophobicContact CD1-CB 4.41Å; I248-L276 HydrophobicContact CD1-CD1 3.79Å
249	E	91.3	Very high	87.3	Confident	127 Å²	127	87.2 Å²	87.2	59%	0.593	43%	0.434	S	S	*	.	H	α-helix	trans	-62.6	-42.1	176.9	-74	-171.8	170.3	0	0	112.2	E245 H246 L251 K252 S253	E245-E249 WeakPolarHBondContact O-CG 3.29Å; E245-E249 PolarHBondContact O-N 3.42Å; H246-E249 PolarHBondContact O-N 3.39Å; E249-L251 VanDerWaalsContact C-N 3.32Å; E249-L251 PolarHBondContact O-N 2.99Å; E249-K252 CarbonylContact O-C 3.58Å; E249-K252 PolarHBondContact O-N 3Å; E249-S253 WeakPolarHBondContact O-CB 3.43Å; E249-S253 PolarHBondContact O-N 3.47Å; E249-S253 PolarHBondContact O-OG 2.88Å
250	N	90.9	Very high	86.5	Confident	73 Å²	73	87.4 Å²	87.4	39%	0.39	45%	0.446	S	S	.	.	H	α-helix	trans	-65.5	-32.3	175.6	-79.5	-41.7	0	0	0	113.3	H246 Q247 S253 K254	H246-N250 PolarHBondContact CE1-ND2 3.01Å; H246-N250 PolarHBondContact ND1-ND2 3.11Å; H246-N250 PolarHBondContact NE2-ND2 2.9Å; H246-N250 WeakPolarHBondContact O-CB 3.45Å; H246-N250 VanDerWaalsContact O-CG 3.31Å; H246-N250 PolarHBondContact O-N 2.96Å; H246-N250 PolarHBondContact O-ND2 2.81Å; Q247-N250 PolarHBondContact O-N 3.49Å; N250-S253 PolarHBondContact O-OG 3.49Å; N250-K254 WeakPolarHBondContact O-CG 3.43Å
251	L	89	Confident	85.8	Confident	20 Å²	20	87.5 Å²	87.5	11%	0.105	45%	0.446	C	S	.	.	H	α-helix	trans	-73.4	-41	172.2	-80.7	162.3	0	0	0	111.6	Q247 I248 E249 S253 K254 D265 L272	Q247-L251 PolarHBondContact O-N 3.16Å; I248-L251 PolarHBondContact O-N 3.16Å; E249-L251 VanDerWaalsContact C-N 3.32Å; E249-L251 PolarHBondContact O-N 2.99Å; L251-S253 VanDerWaalsContact C-N 3.32Å; L251-S253 PolarHBondContact O-N 2.79Å; L251-K254 PolarHBondContact O-N 3.08Å; L251-D265 HydrophobicContact CD2-CB 4.23Å; L251-L272 HydrophobicContact CD1-CD1 3.45Å; L251-L272 VanDerWaalsContact CD1-CD1 3.45Å
252	K	86.6	Confident	85.4	Confident	103 Å²	103	89.2 Å²	89.2	45%	0.448	46%	0.461	S	S	.	.	H	α-helix	trans	-66.6	-33.8	176.3	-74.4	177.7	179.9	172.6	0	111.8	I248 E249 K254 C255 L269 E273	I248-K252 HydrophobicContact CG2-CD 3.88Å; I248-K252 HydrophobicContact CG2-CG 4.39Å; I248-K252 WeakPolarHBondContact O-CB 3.5Å; I248-K252 WeakPolarHBondContact O-CG 3.33Å; I248-K252 PolarHBondContact O-N 3.41Å; E249-K252 CarbonylContact O-C 3.58Å; E249-K252 PolarHBondContact O-N 3Å; K252-K254 PolarHBondContact O-N 2.81Å; K252-C255 WeakPolarHBondContact O-CA 3.44Å; K252-C255 VanDerWaalsContact O-CB 3.26Å; K252-C255 WeakPolarHBondContact O-CB 3.41Å; K252-C255 PolarHBondContact O-N 3.25Å; K252-L269 HydrophobicContact CG-CD1 4.28Å; K252-E273 IonicContact NZ-OE1 3.62Å
253	S	88.1	Confident	84.9	Confident	54 Å²	54	89.2 Å²	89.2	38%	0.378	47%	0.468	S	S	.	.	H	α-helix	trans	-67	-34.9	178.3	73.6	0	0	0	0	112.5	E249 N250 L251 C255 K256	E249-S253 WeakPolarHBondContact O-CB 3.43Å; E249-S253 PolarHBondContact O-N 3.47Å; E249-S253 PolarHBondContact O-OG 2.88Å; N250-S253 PolarHBondContact O-OG 3.49Å; L251-S253 VanDerWaalsContact C-N 3.32Å; L251-S253 PolarHBondContact O-N 2.79Å; S253-C255 PolarHBondContact O-N 2.91Å; S253-C255 VanDerWaalsContact O-N 3.09Å; S253-K256 WeakPolarHBondContact O-CB 3.1Å; S253-K256 PolarHBondContact O-N 3.49Å
254	K	83.4	Confident	84.6	Confident	143 Å²	143	90.6 Å²	90.6	62%	0.622	47%	0.472	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60	-17.4	170.4	-68.9	173.8	-177.3	178.2	0	113.5	N250 L251 K252	N250-K254 WeakPolarHBondContact O-CG 3.43Å; L251-K254 PolarHBondContact O-N 3.08Å; K252-K254 PolarHBondContact O-N 2.81Å
255	C	72.3	Confident	84.3	Confident	35 Å²	35	92.1 Å²	92.1	24%	0.236	48%	0.48	C	S	.	.	T	Hydrogen-bonded Turn	trans	-94.2	-5.6	177.4	-115.6	0	0	0	0	114.2	K252 S253 D257 G258 R259 L261	K252-C255 WeakPolarHBondContact O-CA 3.44Å; K252-C255 VanDerWaalsContact O-CB 3.26Å; K252-C255 WeakPolarHBondContact O-CB 3.41Å; K252-C255 PolarHBondContact O-N 3.25Å; S253-C255 PolarHBondContact O-N 2.91Å; S253-C255 VanDerWaalsContact O-N 3.09Å; C255-D257 PolarHBondContact O-N 3.33Å; C255-D257 VanDerWaalsContact O-N 3.15Å; C255-G258 PolarHBondContact O-N 3.03Å; C255-R259 PolarHBondContact SG-O 3.01Å; C255-L261 HydrophobicContact CB-CD1 4.43Å; C255-L261 WeakPolarHBondContact SG-CD1 3.41Å; C255-L261 WeakPolarHBondContact SG-CG 3.39Å
256	K	72	Confident	83.9	Confident	182 Å²	182	95.8 Å²	95.8	79%	0.791	49%	0.49	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.7	-21.1	-178.1	-85.2	-176.3	172	178.6	0	113.6	S253 G258	S253-K256 WeakPolarHBondContact O-CB 3.1Å; S253-K256 PolarHBondContact O-N 3.49Å; K256-G258 PolarHBondContact O-N 2.93Å
257	D	74.9	Confident	83.6	Confident	138 Å²	138	99.3 Å²	99.3	74%	0.738	50%	0.499	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.4	7.5	178.1	-62.3	-24.9	0	0	0	113.9	C255 R259	C255-D257 PolarHBondContact O-N 3.33Å; C255-D257 VanDerWaalsContact O-N 3.15Å; D257-R259 PolarHBondContact O-N 3.29Å
258	G	70.7	Confident	83.5	Confident	70 Å²	70	98.6 Å²	98.6	72%	0.722	50%	0.498	S	S	*	.	S	Bend	trans	76.3	3.2	178.1	0	0	0	0	0	114.9	C255 K256	C255-G258 PolarHBondContact O-N 3.03Å; K256-G258 PolarHBondContact O-N 2.93Å
259	R	76.6	Confident	83.4	Confident	192 Å²	192	99 Å²	99	73%	0.725	50%	0.5	S	S	*	.	P	Polyproline II helix	trans	-80.6	137.2	174.6	-63.9	-176.8	-175.1	-166.6	1.9	110.2	C255 D257	C255-R259 PolarHBondContact SG-O 3.01Å; D257-R259 PolarHBondContact O-N 3.29Å
260	P	76.3	Confident	83.3	Confident	122 Å²	122	98.1 Å²	98.1	79%	0.792	50%	0.496	S	S	*	.	P	Polyproline II helix	trans	-65	142.5	175.2	26.7	-33	0	0	0	110.8	S262	P260-S262 PolarHBondContact O-N 3.32Å
261	L	78.1	Confident	83.3	Confident	57 Å²	57	99.8 Å²	99.8	30%	0.298	50%	0.501	S	S	.	.	P	Polyproline II helix	trans	-55.3	138.5	173.7	-87.4	130.3	0	0	0	110.6	C255 D265 L269	C255-L261 HydrophobicContact CB-CD1 4.43Å; C255-L261 WeakPolarHBondContact SG-CD1 3.41Å; C255-L261 WeakPolarHBondContact SG-CG 3.39Å; L261-D265 HydrophobicContact CD2-CB 3.42Å; L261-D265 VanDerWaalsContact CD2-CB 3.42Å; L261-L269 HydrophobicContact CD1-CD1 4.35Å
262	S	83.8	Confident	83.5	Confident	64 Å²	64	99.6 Å²	99.6	45%	0.448	50%	0.5	S	S	.	.	P	Polyproline II helix	trans	-56.2	147.8	168.8	-178.6	0	0	0	0	110.1	P260 K264 D265 R266	P260-S262 PolarHBondContact O-N 3.32Å; S262-K264 PolarHBondContact O-N 3.16Å; S262-K264 VanDerWaalsContact O-N 3.11Å; S262-D265 PolarHBondContact O-N 3.39Å; S262-R266 PolarHBondContact O-N 3.05Å
263	S	84.9	Confident	83.7	Confident	92 Å²	92	98.3 Å²	98.3	64%	0.643	50%	0.496	S	S	*	.	H	α-helix	trans	-56.4	-31	179.1	61.5	0	0	0	0	112.6	R267	S263-R267 WeakPolarHBondContact O-CG 3.46Å; S263-R267 PolarHBondContact O-N 3.45Å
264	K	87.5	Confident	83.7	Confident	143 Å²	143	97.2 Å²	97.2	62%	0.622	49%	0.493	S	S	*	.	H	α-helix	trans	-68.9	-48.9	173.2	-175.1	177.8	178.6	-180	0	112	S262 R266 R267 N268	S262-K264 PolarHBondContact O-N 3.16Å; S262-K264 VanDerWaalsContact O-N 3.11Å; K264-R266 VanDerWaalsContact C-N 3.27Å; K264-R266 PolarHBondContact O-N 3.4Å; K264-R267 PolarHBondContact O-N 3.43Å; K264-N268 PolarHBondContact O-N 3.34Å; K264-N268 PolarHBondContact O-OD1 3.31Å
265	D	87.6	Confident	84	Confident	47 Å²	47	95 Å²	95	25%	0.251	48%	0.483	S	S	.	.	H	α-helix	trans	-66.4	-32.5	-178.9	-63.3	-27	0	0	0	111.7	L251 L261 S262 N268 L269	L251-D265 HydrophobicContact CD2-CB 4.23Å; L261-D265 HydrophobicContact CD2-CB 3.42Å; L261-D265 VanDerWaalsContact CD2-CB 3.42Å; S262-D265 PolarHBondContact O-N 3.39Å; D265-N268 PolarHBondContact O-N 3.39Å; D265-L269 VanDerWaalsContact O-CB 3.31Å; D265-L269 WeakPolarHBondContact O-CB 3.37Å; D265-L269 PolarHBondContact O-N 2.89Å
266	R	86.9	Confident	84.8	Confident	152 Å²	152	94.6 Å²	94.6	57%	0.574	48%	0.478	S	S	*	.	H	α-helix	trans	-64	-41	173	-164.3	177.5	77.7	126.3	1.5	112.5	S262 K264 L269 Q270	S262-R266 PolarHBondContact O-N 3.05Å; K264-R266 VanDerWaalsContact C-N 3.27Å; K264-R266 PolarHBondContact O-N 3.4Å; R266-L269 PolarHBondContact O-N 3.15Å; R266-Q270 WeakPolarHBondContact O-CG 3.29Å; R266-Q270 PolarHBondContact O-N 3.33Å; R266-Q270 VanDerWaalsContact O-N 3.08Å
267	R	89.4	Confident	85.6	Confident	186 Å²	186	91 Å²	91	70%	0.702	47%	0.465	S	S	*	.	H	α-helix	trans	-66.1	-43.9	174.7	-72.4	178	-178.7	-171.7	0.5	111.2	S263 K264 L269 Q270 E271	S263-R267 WeakPolarHBondContact O-CG 3.46Å; S263-R267 PolarHBondContact O-N 3.45Å; K264-R267 PolarHBondContact O-N 3.43Å; R267-L269 VanDerWaalsContact C-N 3.3Å; R267-L269 PolarHBondContact O-N 3.11Å; R267-Q270 PolarHBondContact O-N 3.35Å; R267-E271 PolarHBondContact O-N 3.26Å
268	N	89.9	Confident	86.2	Confident	59 Å²	59	86.7 Å²	86.7	32%	0.316	44%	0.443	S	S	.	.	H	α-helix	trans	-60.9	-41.2	176.7	-69.4	-5.3	0	0	0	111.6	K264 D265 E271 L272	K264-N268 PolarHBondContact O-N 3.34Å; K264-N268 PolarHBondContact O-OD1 3.31Å; D265-N268 PolarHBondContact O-N 3.39Å; N268-E271 PolarHBondContact O-N 3.47Å; N268-L272 WeakPolarHBondContact O-CB 3.45Å; N268-L272 VanDerWaalsContact O-CG 3.31Å; N268-L272 WeakPolarHBondContact O-CG 3.33Å; N268-L272 PolarHBondContact O-N 3.27Å
269	L	90.7	Very high	87	Confident	21 Å²	21	84.5 Å²	84.5	11%	0.11	42%	0.415	C	S	.	.	H	α-helix	trans	-62.8	-44.6	176.5	-175.8	152.9	0	0	0	111.2	K252 L261 D265 R266 R267 E271 L272 E273	K252-L269 HydrophobicContact CG-CD1 4.28Å; L261-L269 HydrophobicContact CD1-CD1 4.35Å; D265-L269 VanDerWaalsContact O-CB 3.31Å; D265-L269 WeakPolarHBondContact O-CB 3.37Å; D265-L269 PolarHBondContact O-N 2.89Å; R266-L269 PolarHBondContact O-N 3.15Å; R267-L269 VanDerWaalsContact C-N 3.3Å; R267-L269 PolarHBondContact O-N 3.11Å; L269-E271 VanDerWaalsContact C-N 3.33Å; L269-E271 PolarHBondContact O-N 3.2Å; L269-L272 PolarHBondContact O-N 2.83Å; L269-E273 HydrophobicContact CD2-CG 4.09Å; L269-E273 VanDerWaalsContact CD2-OE1 3.31Å; L269-E273 WeakPolarHBondContact CD2-OE1 3.48Å; L269-E273 WeakPolarHBondContact CD2-OE2 3.37Å; L269-E273 WeakPolarHBondContact O-CB 3.27Å; L269-E273 WeakPolarHBondContact O-CG 3.27Å; L269-E273 PolarHBondContact O-N 3.26Å
270	Q	89.7	Confident	87.6	Confident	108 Å²	108	79.2 Å²	79.2	51%	0.505	40%	0.398	S	S	.	.	H	α-helix	trans	-61.8	-39.9	174.7	-73.7	-179.9	-37.6	0	0	112.5	R266 R267 G274	R266-Q270 WeakPolarHBondContact O-CG 3.29Å; R266-Q270 PolarHBondContact O-N 3.33Å; R266-Q270 VanDerWaalsContact O-N 3.08Å; R267-Q270 PolarHBondContact O-N 3.35Å; Q270-G274 PolarHBondContact O-N 3.46Å
271	E	91.1	Very high	87.9	Confident	108 Å²	108	76.5 Å²	76.5	51%	0.505	37%	0.372	S	S	.	.	H	α-helix	trans	-64.6	-42.3	176.1	-168.7	-171.7	150.5	0	0	111.6	R267 N268 L269 G274 K275	R267-E271 PolarHBondContact O-N 3.26Å; N268-E271 PolarHBondContact O-N 3.47Å; L269-E271 VanDerWaalsContact C-N 3.33Å; L269-E271 PolarHBondContact O-N 3.2Å; E271-G274 PolarHBondContact O-N 3.02Å; E271-K275 WeakPolarHBondContact O-CG 3.37Å; E271-K275 PolarHBondContact O-N 3.35Å; E271-K275 VanDerWaalsContact OE1-CE 3.27Å; E271-K275 WeakPolarHBondContact OE1-CE 3.43Å; E271-K275 IonicContact OE1-NZ 3.88Å; E271-K275 PolarHBondContact OE1-NZ 3.4Å
272	L	92.2	Very high	88.3	Confident	16 Å²	16	76.6 Å²	76.6	8%	0.084	37%	0.369	C	S	.	.	H	α-helix	trans	-67.8	-42.1	177.3	-72.9	166.4	0	0	0	112.2	V244 Q247 I248 L251 N268 L269 G274 K275 L276	V244-L272 HydrophobicContact CG1-CB 4.36Å; V244-L272 HydrophobicContact CG1-CD2 4.14Å; Q247-L272 HydrophobicContact CB-CD1 4.19Å; Q247-L272 HydrophobicContact CB-CD2 4.48Å; Q247-L272 VanDerWaalsContact OE1-CD2 3.29Å; I248-L272 HydrophobicContact CD1-CB 4.15Å; I248-L272 HydrophobicContact CG1-CB 3.78Å; I248-L272 HydrophobicContact CG1-CD1 4.38Å; L251-L272 HydrophobicContact CD1-CD1 3.45Å; L251-L272 VanDerWaalsContact CD1-CD1 3.45Å; N268-L272 WeakPolarHBondContact O-CB 3.45Å; N268-L272 VanDerWaalsContact O-CG 3.31Å; N268-L272 WeakPolarHBondContact O-CG 3.33Å; N268-L272 PolarHBondContact O-N 3.27Å; L269-L272 PolarHBondContact O-N 2.83Å; L272-G274 VanDerWaalsContact C-N 3.31Å; L272-G274 PolarHBondContact O-N 3.04Å; L272-K275 PolarHBondContact O-N 2.86Å; L272-L276 WeakPolarHBondContact O-CB 3.43Å; L272-L276 PolarHBondContact O-N 2.92Å
273	E	90.9	Very high	88.3	Confident	76 Å²	76	74.1 Å²	74.1	36%	0.355	35%	0.353	S	S	.	.	H	α-helix	trans	-62	-39.9	173.9	-74.9	179.9	165.7	0	0	111.2	I248 K252 L269 L276 Q277	I248-E273 HydrophobicContact CD1-CG 4.32Å; K252-E273 IonicContact NZ-OE1 3.62Å; L269-E273 HydrophobicContact CD2-CG 4.09Å; L269-E273 VanDerWaalsContact CD2-OE1 3.31Å; L269-E273 WeakPolarHBondContact CD2-OE1 3.48Å; L269-E273 WeakPolarHBondContact CD2-OE2 3.37Å; L269-E273 WeakPolarHBondContact O-CB 3.27Å; L269-E273 WeakPolarHBondContact O-CG 3.27Å; L269-E273 PolarHBondContact O-N 3.26Å; E273-L276 PolarHBondContact O-N 3.43Å; E273-Q277 WeakPolarHBondContact O-CG 3.19Å; E273-Q277 PolarHBondContact O-N 3.3Å
274	G	88.6	Confident	88.3	Confident	30 Å²	30	76 Å²	76	31%	0.309	35%	0.346	S	S	.	.	H	α-helix	trans	-62.1	-45.3	172.3	0	0	0	0	0	112.6	Q270 E271 L272 L276 Q277 V278	Q270-G274 PolarHBondContact O-N 3.46Å; E271-G274 PolarHBondContact O-N 3.02Å; L272-G274 VanDerWaalsContact C-N 3.31Å; L272-G274 PolarHBondContact O-N 3.04Å; G274-L276 VanDerWaalsContact C-N 3.35Å; G274-L276 PolarHBondContact O-N 3.32Å; G274-Q277 PolarHBondContact O-N 3.33Å; G274-V278 WeakPolarHBondContact O-CG2 3.44Å; G274-V278 PolarHBondContact O-N 3.46Å; G274-V278 VanDerWaalsContact O-N 3.11Å
275	K	89.3	Confident	88	Confident	97 Å²	97	70.1 Å²	70.1	42%	0.422	32%	0.321	S	S	.	.	H	α-helix	trans	-60.2	-43.3	174.5	-75.5	175	-173.9	165.1	0	111.9	E271 L272 Q277 V278 L279	E271-K275 WeakPolarHBondContact O-CG 3.37Å; E271-K275 PolarHBondContact O-N 3.35Å; E271-K275 VanDerWaalsContact OE1-CE 3.27Å; E271-K275 WeakPolarHBondContact OE1-CE 3.43Å; E271-K275 IonicContact OE1-NZ 3.88Å; E271-K275 PolarHBondContact OE1-NZ 3.4Å; L272-K275 PolarHBondContact O-N 2.86Å; K275-Q277 PolarHBondContact O-N 2.86Å; K275-V278 PolarHBondContact O-N 3.5Å; K275-L279 WeakPolarHBondContact O-CG 3.4Å; K275-L279 PolarHBondContact O-N 3.3Å
276	L	90.6	Very high	87.8	Confident	26 Å²	26	67.9 Å²	67.9	14%	0.136	31%	0.309	C	S	.	.	H	α-helix	trans	-61.1	-44	177.8	-177.5	146.2	0	0	0	111.5	V244 E245 I248 L272 E273 G274 V278 L279 Q280	V244-L276 HydrophobicContact CG1-CB 3.98Å; V244-L276 HydrophobicContact CG1-CD1 4.39Å; E245-L276 HydrophobicContact CG-CD1 3.47Å; E245-L276 VanDerWaalsContact CG-CD1 3.47Å; I248-L276 HydrophobicContact CD1-CB 4.41Å; I248-L276 HydrophobicContact CD1-CD1 3.79Å; L272-L276 WeakPolarHBondContact O-CB 3.43Å; L272-L276 PolarHBondContact O-N 2.92Å; E273-L276 PolarHBondContact O-N 3.43Å; G274-L276 VanDerWaalsContact C-N 3.35Å; G274-L276 PolarHBondContact O-N 3.32Å; L276-V278 VanDerWaalsContact C-N 3.31Å; L276-V278 PolarHBondContact O-N 3.49Å; L276-L279 PolarHBondContact O-N 2.77Å; L276-Q280 VanDerWaalsContact CD2-CD 3.48Å; L276-Q280 HydrophobicContact CD2-CG 4.15Å; L276-Q280 WeakPolarHBondContact O-CB 3.31Å; L276-Q280 WeakPolarHBondContact O-CG 3.48Å; L276-Q280 PolarHBondContact O-N 3.01Å
277	Q	88.3	Confident	87.5	Confident	108 Å²	108	64 Å²	64	51%	0.505	30%	0.299	S	S	.	.	H	α-helix	trans	-59.3	-42.1	174.6	-72.5	178.5	1.8	0	0	112	E273 G274 K275 Q280 R281	E273-Q277 WeakPolarHBondContact O-CG 3.19Å; E273-Q277 PolarHBondContact O-N 3.3Å; G274-Q277 PolarHBondContact O-N 3.33Å; K275-Q277 PolarHBondContact O-N 2.86Å; Q277-Q280 PolarHBondContact O-N 3.37Å; Q277-R281 VanDerWaalsContact O-CG 3.31Å; Q277-R281 WeakPolarHBondContact O-CG 3.22Å; Q277-R281 PolarHBondContact O-N 3.04Å
278	V	86.3	Confident	86.9	Confident	46 Å²	46	58.3 Å²	58.3	28%	0.279	28%	0.282	S	S	.	.	H	α-helix	trans	-64.8	-45.1	176.8	173.7	0	0	0	0	111.4	G274 K275 L276 Q280 R281 R282	G274-V278 WeakPolarHBondContact O-CG2 3.44Å; G274-V278 PolarHBondContact O-N 3.46Å; G274-V278 VanDerWaalsContact O-N 3.11Å; K275-V278 PolarHBondContact O-N 3.5Å; L276-V278 VanDerWaalsContact C-N 3.31Å; L276-V278 PolarHBondContact O-N 3.49Å; V278-Q280 PolarHBondContact O-N 2.84Å; V278-R281 PolarHBondContact O-N 3.01Å; V278-R282 WeakPolarHBondContact O-CB 3.37Å; V278-R282 PolarHBondContact O-N 3.25Å
279	L	88.1	Confident	86.2	Confident	24 Å²	24	56.9 Å²	56.9	13%	0.126	28%	0.279	C	S	.	.	H	α-helix	trans	-64.2	-39.1	177.8	-70.8	171.5	0	0	0	112.1	N237 D240 I241 V244 K275 L276 R282 G283	N237-L279 PolarHBondContact ND2-O 2.87Å; N237-L279 WeakPolarHBondContact OD1-CD2 3.09Å; N237-L279 PolarHBondContact OD1-O 2.7Å; D240-L279 HydrophobicContact CB-CD1 3.93Å; D240-L279 HydrophobicContact CB-CD2 3.98Å; I241-L279 HydrophobicContact CD1-CB 4.27Å; I241-L279 HydrophobicContact CG1-CB 3.65Å; I241-L279 HydrophobicContact CG1-CD1 4.28Å; V244-L279 HydrophobicContact CG2-CD1 3.98Å; K275-L279 WeakPolarHBondContact O-CG 3.4Å; K275-L279 PolarHBondContact O-N 3.3Å; L276-L279 PolarHBondContact O-N 2.77Å; L279-R282 WeakPolarHBondContact O-CB 3.39Å; L279-R282 PolarHBondContact O-N 3.26Å; L279-G283 PolarHBondContact O-N 2.92Å
280	Q	88.9	Confident	85.4	Confident	81 Å²	81	60.2 Å²	60.2	38%	0.379	29%	0.294	S	S	.	.	H	α-helix	trans	-66.2	-38.9	174.4	-75.5	-177	-15.4	0	0	112.4	L276 Q277 V278 G283 R284	L276-Q280 VanDerWaalsContact CD2-CD 3.48Å; L276-Q280 HydrophobicContact CD2-CG 4.15Å; L276-Q280 WeakPolarHBondContact O-CB 3.31Å; L276-Q280 WeakPolarHBondContact O-CG 3.48Å; L276-Q280 PolarHBondContact O-N 3.01Å; Q277-Q280 PolarHBondContact O-N 3.37Å; V278-Q280 PolarHBondContact O-N 2.84Å; Q280-G283 PolarHBondContact O-N 3.29Å; Q280-R284 PolarHBondContact O-N 3.45Å; Q280-R284 VanDerWaalsContact O-N 3.1Å
281	R	83.9	Confident	84.3	Confident	66 Å²	66	59.4 Å²	59.4	25%	0.249	30%	0.3	C	S	.	.	H	α-helix	trans	-62.4	-45.1	171.8	-74.1	176.9	-171.2	-175.9	1.8	110.7	Q277 V278 G283 R284 H285 V524 D528	Q277-R281 VanDerWaalsContact O-CG 3.31Å; Q277-R281 WeakPolarHBondContact O-CG 3.22Å; Q277-R281 PolarHBondContact O-N 3.04Å; V278-R281 PolarHBondContact O-N 3.01Å; R281-G283 VanDerWaalsContact C-N 3.33Å; R281-G283 PolarHBondContact O-N 3.24Å; R281-R284 PolarHBondContact O-N 3.05Å; R281-H285 PolarHBondContact O-CD2 2.98Å; R281-H285 PolarHBondContact O-N 3.34Å; R281-V524 HydrophobicContact CB-CG1 4.31Å; R281-D528 PolarHBondContact NH1-O 3.23Å
282	R	84.6	Confident	83.1	Confident	59 Å²	59	59.5 Å²	59.5	22%	0.223	30%	0.3	C	S	.	.	H	α-helix	trans	-60.1	-42.1	176.4	-172	173.9	-179.5	-154.4	-1.1	111.9	N237 V278 L279 H285 L286 I520 V524	N237-R282 WeakPolarHBondContact OD1-CD 3.42Å; V278-R282 WeakPolarHBondContact O-CB 3.37Å; V278-R282 PolarHBondContact O-N 3.25Å; L279-R282 WeakPolarHBondContact O-CB 3.39Å; L279-R282 PolarHBondContact O-N 3.26Å; R282-H285 PolarHBondContact O-N 3.16Å; R282-L286 HydrophobicContact CG-CD1 4.38Å; R282-L286 WeakPolarHBondContact O-CG 3.36Å; R282-L286 PolarHBondContact O-N 3.27Å; R282-I520 HydrophobicContact CG-CD1 4.49Å; R282-V524 HydrophobicContact CB-CG1 4.32Å
283	G	85.2	Confident	81.4	Confident	12 Å²	12	63.4 Å²	63.4	12%	0.124	33%	0.328	C	S	.	.	H	α-helix	trans	-58.5	-47.5	174.9	0	0	0	0	0	112.8	N237 L279 Q280 R281 H285 L286 D287	N237-G283 PolarHBondContact ND2-N 3.49Å; L279-G283 PolarHBondContact O-N 2.92Å; Q280-G283 PolarHBondContact O-N 3.29Å; R281-G283 VanDerWaalsContact C-N 3.33Å; R281-G283 PolarHBondContact O-N 3.24Å; G283-H285 VanDerWaalsContact C-N 3.31Å; G283-H285 PolarHBondContact O-N 2.89Å; G283-L286 WeakPolarHBondContact O-CB 3.42Å; G283-L286 PolarHBondContact O-N 3.36Å; G283-L286 VanDerWaalsContact O-N 3.08Å; G283-D287 PolarHBondContact O-N 3Å
284	R	83.4	Confident	79.8	Confident	131 Å²	131	64.1 Å²	64.1	49%	0.494	34%	0.34	S	S	.	.	H	α-helix	trans	-57.4	-42.3	176	-76	-176.5	-93.8	160.2	-9.5	112.5	Q280 R281 D287 I288	Q280-R284 PolarHBondContact O-N 3.45Å; Q280-R284 VanDerWaalsContact O-N 3.1Å; R281-R284 PolarHBondContact O-N 3.05Å; R284-D287 PolarHBondContact O-N 3.24Å; R284-I288 VanDerWaalsContact O-CG1 3.29Å; R284-I288 WeakPolarHBondContact O-CG1 3.17Å; R284-I288 PolarHBondContact O-N 2.93Å; R284-I288 VanDerWaalsContact O-N 3.1Å
285	H	82.2	Confident	78.6	Confident	20 Å²	20	65.7 Å²	65.7	9%	0.093	35%	0.346	C	S	.	.	H	α-helix	trans	-67.3	-36.8	175.7	-84.1	-101.1	0	0	0	112.9	R281 R282 G283 I288 A289 I520 E523 V524 Y536	R281-H285 PolarHBondContact O-CD2 2.98Å; R281-H285 PolarHBondContact O-N 3.34Å; R282-H285 PolarHBondContact O-N 3.16Å; G283-H285 VanDerWaalsContact C-N 3.31Å; G283-H285 PolarHBondContact O-N 2.89Å; H285-I288 PolarHBondContact O-N 3.39Å; H285-A289 WeakPolarHBondContact O-CB 3.3Å; H285-A289 PolarHBondContact O-N 3.42Å; H285-I520 HydrophobicContact CB-CD1 3.78Å; H285-I520 HydrophobicContact CB-CG2 4.12Å; H285-E523 IonicContact CE1-OE2 3.36Å; H285-E523 IonicContact ND1-OE2 3.95Å; H285-E523 PolarHBondContact ND1-OE2 3.16Å; H285-V524 HydrophobicContact CB-CG2 4.06Å; H285-V524 VanDerWaalsContact CD2-CG2 3.4Å; H285-V524 WeakPolarHBondContact CD2-CG2 3.25Å; H285-Y536 PolarHBondContact CE1-OH 3.18Å
286	L	82.4	Confident	77.5	Confident	0 Å²	0	69.2 Å²	69.2	0%	0	36%	0.361	C	S	.	.	H	α-helix	trans	-63.1	-42.7	174.6	-72.3	165.6	0	0	0	111.3	V230 E233 R234 N237 R282 G283 A289 E290 I520	V230-L286 HydrophobicContact CG1-CD2 4.23Å; E233-L286 HydrophobicContact CB-CD1 4.41Å; E233-L286 HydrophobicContact CB-CD2 3.91Å; R234-L286 HydrophobicContact CB-CD1 4.3Å; N237-L286 HydrophobicContact CB-CD1 3.9Å; R282-L286 HydrophobicContact CG-CD1 4.38Å; R282-L286 WeakPolarHBondContact O-CG 3.36Å; R282-L286 PolarHBondContact O-N 3.27Å; G283-L286 WeakPolarHBondContact O-CB 3.42Å; G283-L286 PolarHBondContact O-N 3.36Å; G283-L286 VanDerWaalsContact O-N 3.08Å; L286-A289 PolarHBondContact O-N 2.77Å; L286-E290 PolarHBondContact O-N 2.92Å; L286-I520 HydrophobicContact CB-CD1 4.07Å; L286-I520 HydrophobicContact CD1-CD1 4.32Å; L286-I520 HydrophobicContact CD2-CD1 3.22Å; L286-I520 HydrophobicContact CD2-CG1 4.03Å; L286-I520 HydrophobicContact CG-CD1 3.22Å; L286-I520 HydrophobicContact CG-CG1 4.48Å
287	D	81	Confident	76.3	Confident	70 Å²	70	71.8 Å²	71.8	37%	0.374	38%	0.378	S	S	.	.	H	α-helix	trans	-63.8	-42.6	178.4	-69.5	-25.2	0	0	0	111.5	R234 G283 R284 E290 S291	R234-D287 IonicContact CZ-OD1 3.44Å; R234-D287 IonicContact NE-OD1 3.69Å; R234-D287 PolarHBondContact NE-OD1 2.67Å; R234-D287 IonicContact NH2-OD1 2.81Å; R234-D287 PolarHBondContact NH2-OD1 2.74Å; R234-D287 VanDerWaalsContact NH2-OD1 3.13Å; G283-D287 PolarHBondContact O-N 3Å; R284-D287 PolarHBondContact O-N 3.24Å; D287-E290 PolarHBondContact O-N 3.42Å; D287-S291 PolarHBondContact O-N 3.33Å; D287-S291 VanDerWaalsContact O-N 3.11Å
288	I	78	Confident	75.3	Confident	67 Å²	67	67.7 Å²	67.7	34%	0.344	37%	0.365	S	S	.	.	H	α-helix	trans	-62.6	-44.6	174.8	-66.3	164.4	0	0	0	110.5	R284 H285 E290 S291 Y536	R284-I288 VanDerWaalsContact O-CG1 3.29Å; R284-I288 WeakPolarHBondContact O-CG1 3.17Å; R284-I288 PolarHBondContact O-N 2.93Å; R284-I288 VanDerWaalsContact O-N 3.1Å; H285-I288 PolarHBondContact O-N 3.39Å; I288-E290 VanDerWaalsContact C-N 3.28Å; I288-E290 PolarHBondContact O-N 3.44Å; I288-S291 PolarHBondContact O-N 3.45Å; I288-S291 PolarHBondContact O-OG 3.35Å; I288-Y536 HydrophobicContact CD1-CD1 4.28Å; I288-Y536 HydrophobicContact CD1-CE1 3.74Å
289	A	74.1	Confident	74.4	Confident	29 Å²	29	69.7 Å²	69.7	24%	0.24	38%	0.381	C	S	.	.	H	α-helix	trans	-64.4	-31.1	179.4	0	0	0	0	0	113.1	H285 L286	H285-A289 WeakPolarHBondContact O-CB 3.3Å; H285-A289 PolarHBondContact O-N 3.42Å; L286-A289 PolarHBondContact O-N 2.77Å
290	E	74.4	Confident	73.9	Confident	90 Å²	90	72.1 Å²	72.1	42%	0.421	41%	0.405	S	S	.	.	H	α-helix	trans	-71.6	-42.4	175.2	-172.7	172.5	-172.7	0	0	111.9	V230 R234 L286 D287 I288 H292	V230-E290 HydrophobicContact CG1-CB 4.13Å; R234-E290 IonicContact CZ-OE2 3.16Å; R234-E290 IonicContact NE-OE2 3.78Å; R234-E290 IonicContact NH1-OE2 3.8Å; R234-E290 PolarHBondContact NH1-OE2 2.87Å; L286-E290 PolarHBondContact O-N 2.92Å; D287-E290 PolarHBondContact O-N 3.42Å; I288-E290 VanDerWaalsContact C-N 3.28Å; I288-E290 PolarHBondContact O-N 3.44Å; E290-H292 VanDerWaalsContact C-N 3.26Å; E290-H292 PolarHBondContact O-N 2.99Å
291	S	66.6	Low	73.5	Confident	91 Å²	91	72.2 Å²	72.2	64%	0.636	41%	0.407	S	S	*	.	H	α-helix	trans	-65.1	-24.3	-175.6	74.4	0	0	0	0	114.4	D287 I288 C293	D287-S291 PolarHBondContact O-N 3.33Å; D287-S291 VanDerWaalsContact O-N 3.11Å; I288-S291 PolarHBondContact O-N 3.45Å; I288-S291 PolarHBondContact O-OG 3.35Å; S291-C293 PolarHBondContact O-N 3.34Å
292	H	66.5	Low	73.6	Confident	111 Å²	111	72.5 Å²	72.5	51%	0.514	41%	0.409	S	S	.	.	S	Bend	trans	-75.7	125.2	-178.3	-98.2	-98.5	0	0	0	112.2	E290 C294 S295	E290-H292 VanDerWaalsContact C-N 3.26Å; E290-H292 PolarHBondContact O-N 2.99Å; H292-C294 HydrophobicContact CB-CB 4.37Å; H292-C294 PolarHBondContact O-N 3.32Å; H292-S295 PolarHBondContact O-N 3.47Å; H292-S295 PolarHBondContact O-OG 2.69Å
293	C	55.3	Low	73.7	Confident	98 Å²	98	73.3 Å²	73.3	66%	0.662	42%	0.421	S	S	*	.	T	Hydrogen-bonded Turn	trans	-50.2	-21.4	171.3	-173.8	0	0	0	0	113.7	S291 S295 K296 V297	S291-C293 PolarHBondContact O-N 3.34Å; C293-S295 PolarHBondContact O-N 3.01Å; C293-K296 PolarHBondContact O-N 3.47Å; C293-V297 PolarHBondContact O-N 2.94Å
294	C	58.3	Low	73.9	Confident	91 Å²	91	76.9 Å²	76.9	62%	0.615	44%	0.44	S	S	*	.	H	α-helix	trans	-58	-24.6	173.1	-71.5	0	0	0	0	114.7	H292 G298	H292-C294 HydrophobicContact CB-CB 4.37Å; H292-C294 PolarHBondContact O-N 3.32Å; C294-G298 WeakPolarHBondContact O-CA 3.36Å; C294-G298 PolarHBondContact O-N 3.31Å
295	S	63.6	Low	74.2	Confident	63 Å²	63	74.5 Å²	74.5	44%	0.441	43%	0.434	S	S	.	.	H	α-helix	trans	-67.5	-40	176.2	67.2	0	0	0	0	111.7	H292 C293 G298 S299	H292-S295 PolarHBondContact O-N 3.47Å; H292-S295 PolarHBondContact O-OG 2.69Å; C293-S295 PolarHBondContact O-N 3.01Å; S295-G298 PolarHBondContact O-N 2.87Å; S295-S299 PolarHBondContact O-N 3.39Å
296	K	65.6	Low	74.6	Confident	170 Å²	170	76.5 Å²	76.5	74%	0.739	44%	0.444	S	S	*	.	H	α-helix	trans	-68.8	-45.7	177.6	-126.8	169.1	-173.1	168.3	0	111.9	C293 G298 S299 A300	C293-K296 PolarHBondContact O-N 3.47Å; K296-G298 VanDerWaalsContact C-N 3.33Å; K296-S299 PolarHBondContact O-N 3.44Å; K296-A300 PolarHBondContact O-N 3.28Å
297	V	66.3	Low	75.1	Confident	80 Å²	80	82.2 Å²	82.2	49%	0.485	47%	0.474	S	S	.	.	H	α-helix	trans	-65.4	-37.3	174	178.7	0	0	0	0	111.2	C293 S299 A300 L301	C293-V297 PolarHBondContact O-N 2.94Å; V297-S299 VanDerWaalsContact C-N 3.32Å; V297-S299 PolarHBondContact O-N 3.44Å; V297-A300 PolarHBondContact O-N 2.82Å; V297-L301 HydrophobicContact CG1-CD1 4.04Å; V297-L301 PolarHBondContact O-N 3.27Å
298	G	66.3	Low	75.7	Confident	23 Å²	23	82.5 Å²	82.5	24%	0.237	48%	0.475	C	S	.	.	H	α-helix	trans	-65	-33	176.5	0	0	0	0	0	113.6	C294 S295 K296 R302	C294-G298 WeakPolarHBondContact O-CA 3.36Å; C294-G298 PolarHBondContact O-N 3.31Å; S295-G298 PolarHBondContact O-N 2.87Å; K296-G298 VanDerWaalsContact C-N 3.33Å; G298-R302 PolarHBondContact O-N 3.27Å
299	S	67.9	Low	76.4	Confident	88 Å²	88	79.3 Å²	79.3	62%	0.615	46%	0.459	S	S	*	.	H	α-helix	trans	-70.7	-41.6	173.3	-165.7	0	0	0	0	111.7	S295 K296 V297 L301 R302	S295-S299 PolarHBondContact O-N 3.39Å; K296-S299 PolarHBondContact O-N 3.44Å; V297-S299 VanDerWaalsContact C-N 3.32Å; V297-S299 PolarHBondContact O-N 3.44Å; S299-L301 VanDerWaalsContact C-N 3.35Å; S299-L301 PolarHBondContact O-N 2.83Å; S299-R302 WeakPolarHBondContact O-CB 3.36Å; S299-R302 PolarHBondContact O-N 3.39Å; S299-R302 VanDerWaalsContact O-N 3.15Å
300	A	77.4	Confident	77.4	Confident	74 Å²	74	81.3 Å²	81.3	61%	0.612	47%	0.468	S	S	*	.	H	α-helix	trans	-65.8	-33.4	175.8	0	0	0	0	0	113.4	K296 V297 R302 P303	K296-A300 PolarHBondContact O-N 3.28Å; V297-A300 PolarHBondContact O-N 2.82Å; A300-R302 PolarHBondContact O-N 2.86Å; A300-P303 WeakPolarHBondContact O-CD 3.41Å
301	L	81.3	Confident	78.4	Confident	84 Å²	84	82.5 Å²	82.5	44%	0.44	47%	0.472	S	S	.	.	T	Hydrogen-bonded Turn	trans	-80.6	1.6	175.6	-71.9	169.8	0	0	0	113.7	V297 S299 V304 K305	V297-L301 HydrophobicContact CG1-CD1 4.04Å; V297-L301 PolarHBondContact O-N 3.27Å; S299-L301 VanDerWaalsContact C-N 3.35Å; S299-L301 PolarHBondContact O-N 2.83Å; L301-V304 PolarHBondContact O-N 3.28Å; L301-K305 WeakPolarHBondContact O-CG 3.41Å; L301-K305 PolarHBondContact O-N 3.46Å
302	R	84.6	Confident	79.7	Confident	72 Å²	72	79.7 Å²	79.7	27%	0.272	45%	0.448	S	S	.	.	H	α-helix	trans	-59	-50.1	-179.6	-173.5	62.2	179.1	-179.1	4.2	114.5	I224 K225 G226 G298 S299 A300 V304 K305 I306	I224-R302 PolarHBondContact O-NH2 2.94Å; K225-R302 PolarHBondContact O-NH2 2.88Å; G226-R302 VanDerWaalsContact N-NH2 3.15Å; G298-R302 PolarHBondContact O-N 3.27Å; S299-R302 WeakPolarHBondContact O-CB 3.36Å; S299-R302 PolarHBondContact O-N 3.39Å; S299-R302 VanDerWaalsContact O-N 3.15Å; A300-R302 PolarHBondContact O-N 2.86Å; R302-V304 VanDerWaalsContact C-N 3.27Å; R302-V304 PolarHBondContact O-N 3.25Å; R302-K305 PolarHBondContact O-N 3.25Å; R302-I306 HydrophobicContact CG-CD1 4.21Å; R302-I306 WeakPolarHBondContact O-CG1 3.39Å; R302-I306 PolarHBondContact O-N 2.87Å; R302-I306 VanDerWaalsContact O-N 3.08Å
303	P	88	Confident	81	Confident	75 Å²	75	76.4 Å²	76.4	49%	0.487	43%	0.434	S	S	.	.	H	α-helix	trans	-58.4	-40.1	177	21.5	-34	0	0	0	111.9	A300 K305 I306 I307	A300-P303 WeakPolarHBondContact O-CD 3.41Å; P303-K305 PolarHBondContact O-N 3.31Å; P303-I306 PolarHBondContact O-N 3.15Å; P303-I307 WeakPolarHBondContact O-CG1 3.25Å; P303-I307 PolarHBondContact O-N 2.79Å
304	V	89.1	Confident	82.9	Confident	87 Å²	87	76.9 Å²	76.9	53%	0.527	43%	0.429	S	S	.	.	H	α-helix	trans	-61.5	-43.3	176.9	-179.7	0	0	0	0	111.3	L301 R302 I306 I307 L308	L301-V304 PolarHBondContact O-N 3.28Å; R302-V304 VanDerWaalsContact C-N 3.27Å; R302-V304 PolarHBondContact O-N 3.25Å; V304-I306 VanDerWaalsContact C-N 3.33Å; V304-I306 PolarHBondContact O-N 3.25Å; V304-I307 PolarHBondContact O-N 3.06Å; V304-L308 WeakPolarHBondContact O-CB 3.11Å; V304-L308 PolarHBondContact O-N 3.33Å
305	K	89.1	Confident	84.6	Confident	82 Å²	82	73.8 Å²	73.8	36%	0.357	41%	0.407	S	S	.	.	H	α-helix	trans	-62.7	-37.7	176.1	-71.3	173.9	-177.6	172.7	0	112.6	L223 L301 R302 P303 G309	L223-K305 HydrophobicContact CD2-CB 4.44Å; L301-K305 WeakPolarHBondContact O-CG 3.41Å; L301-K305 PolarHBondContact O-N 3.46Å; R302-K305 PolarHBondContact O-N 3.25Å; P303-K305 PolarHBondContact O-N 3.31Å; K305-G309 PolarHBondContact O-N 3.07Å
306	I	91.4	Very high	86.1	Confident	62 Å²	62	70.9 Å²	70.9	32%	0.318	39%	0.387	S	S	.	.	H	α-helix	trans	-67.5	-47.5	177.3	-65.6	169.1	0	0	0	110.1	R302 P303 V304 L308 G309 V310	R302-I306 HydrophobicContact CG-CD1 4.21Å; R302-I306 WeakPolarHBondContact O-CG1 3.39Å; R302-I306 PolarHBondContact O-N 2.87Å; R302-I306 VanDerWaalsContact O-N 3.08Å; P303-I306 PolarHBondContact O-N 3.15Å; V304-I306 VanDerWaalsContact C-N 3.33Å; V304-I306 PolarHBondContact O-N 3.25Å; I306-L308 VanDerWaalsContact C-N 3.31Å; I306-L308 PolarHBondContact O-N 3.23Å; I306-G309 PolarHBondContact O-N 3.08Å; I306-G309 VanDerWaalsContact O-N 3.1Å; I306-V310 WeakPolarHBondContact O-CG2 3.45Å; I306-V310 PolarHBondContact O-N 3.23Å
307	I	93.6	Very high	87.5	Confident	120 Å²	120	66.2 Å²	66.2	62%	0.615	37%	0.37	S	S	*	.	H	α-helix	trans	-57.7	-46.1	176.8	-67.3	165.9	0	0	0	110.4	P303 V304 G309 V310 F311	P303-I307 WeakPolarHBondContact O-CG1 3.25Å; P303-I307 PolarHBondContact O-N 2.79Å; V304-I307 PolarHBondContact O-N 3.06Å; I307-G309 VanDerWaalsContact C-N 3.32Å; I307-G309 PolarHBondContact O-N 3.33Å; I307-V310 PolarHBondContact O-N 3.35Å; I307-F311 WeakPolarHBondContact O-CB 3.37Å; I307-F311 PolarHBondContact O-N 3.46Å
308	L	92.3	Very high	88.8	Confident	76 Å²	76	65.1 Å²	65.1	40%	0.398	36%	0.361	S	S	.	.	H	α-helix	trans	-60.6	-41.1	176.3	-169.4	75.3	0	0	0	112	L223 V304 I306 F311 F312	L223-L308 HydrophobicContact CD1-CD2 4.3Å; V304-L308 WeakPolarHBondContact O-CB 3.11Å; V304-L308 PolarHBondContact O-N 3.33Å; I306-L308 VanDerWaalsContact C-N 3.31Å; I306-L308 PolarHBondContact O-N 3.23Å; L308-F311 PolarHBondContact O-N 2.98Å; L308-F312 HydrophobicContact CD1-CE2 3.88Å; L308-F312 HydrophobicContact CD1-CZ 4.21Å; L308-F312 HydrophobicContact CD2-CE2 3.83Å; L308-F312 HydrophobicContact CG-CD2 3.93Å; L308-F312 HydrophobicContact CG-CE2 3.51Å; L308-F312 HydrophobicContact CG-CZ 4.33Å; L308-F312 WeakPolarHBondContact O-CD2 3.1Å; L308-F312 PolarHBondContact O-N 3.33Å
309	G	93.4	Very high	90.1	Very high	0 Å²	0	64.3 Å²	64.3	0%	0	35%	0.351	C	S	.	.	H	α-helix	trans	-62.4	-46.7	175.4	0	0	0	0	0	112.5	P220 K305 I306 I307 F311 F312 I313	P220-G309 VanDerWaalsContact CB-O 3.22Å; P220-G309 WeakPolarHBondContact CB-O 3.34Å; K305-G309 PolarHBondContact O-N 3.07Å; I306-G309 PolarHBondContact O-N 3.08Å; I306-G309 VanDerWaalsContact O-N 3.1Å; I307-G309 VanDerWaalsContact C-N 3.32Å; I307-G309 PolarHBondContact O-N 3.33Å; G309-F311 PolarHBondContact O-N 3.03Å; G309-F312 PolarHBondContact O-N 3.28Å; G309-I313 WeakPolarHBondContact O-CG1 3.49Å; G309-I313 PolarHBondContact O-N 3.1Å; G309-I313 VanDerWaalsContact O-N 3.08Å
310	V	94.5	Very high	91.4	Very high	71 Å²	71	60.8 Å²	60.8	43%	0.43	33%	0.326	S	S	.	.	H	α-helix	trans	-61.1	-45.4	176.2	173.4	0	0	0	0	110.8	I224 I306 I307 F312 I313 L314	I224-V310 HydrophobicContact CD1-CG2 4.16Å; I306-V310 WeakPolarHBondContact O-CG2 3.45Å; I306-V310 PolarHBondContact O-N 3.23Å; I307-V310 PolarHBondContact O-N 3.35Å; V310-F312 VanDerWaalsContact C-N 3.33Å; V310-F312 PolarHBondContact O-N 3.1Å; V310-I313 PolarHBondContact O-N 3.02Å; V310-I313 VanDerWaalsContact O-N 3.15Å; V310-L314 HydrophobicContact CG1-CD1 4.42Å; V310-L314 WeakPolarHBondContact O-CG 3.3Å; V310-L314 PolarHBondContact O-N 3.45Å
311	F	94.6	Very high	92.2	Very high	115 Å²	115	61.7 Å²	61.7	50%	0.504	32%	0.319	S	S	.	.	H	α-helix	trans	-55.5	-46.9	175.4	174.2	-100.2	0	0	0	112	I307 L308 G309 I313 L314 V315	I307-F311 WeakPolarHBondContact O-CB 3.37Å; I307-F311 PolarHBondContact O-N 3.46Å; L308-F311 PolarHBondContact O-N 2.98Å; G309-F311 PolarHBondContact O-N 3.03Å; F311-I313 VanDerWaalsContact C-N 3.33Å; F311-I313 PolarHBondContact O-N 3.27Å; F311-L314 WeakPolarHBondContact O-CB 3.43Å; F311-L314 PolarHBondContact O-N 3.36Å; F311-L314 VanDerWaalsContact O-N 3.17Å; F311-V315 HydrophobicContact CD1-CG2 4.35Å; F311-V315 HydrophobicContact CE1-CG2 3.9Å; F311-V315 HydrophobicContact CE2-CG2 4.17Å; F311-V315 HydrophobicContact CZ-CG2 3.79Å; F311-V315 WeakPolarHBondContact O-CG2 3.33Å; F311-V315 PolarHBondContact O-N 3.42Å
312	F	94.8	Very high	92.8	Very high	32 Å²	32	57.7 Å²	57.7	14%	0.14	30%	0.298	C	S	.	.	H	α-helix	trans	-67.3	-28.2	178.6	-75.6	-46.5	0	0	0	114.1	M219 P220 L223 L308 G309 V310 A316 Y376	M219-F312 HydrophobicContact CE-CD2 4.28Å; M219-F312 HydrophobicContact CE-CE2 3.87Å; M219-F312 HydrophobicContact CE-CZ 4.27Å; P220-F312 HydrophobicContact CB-CB 3.94Å; L223-F312 HydrophobicContact CD1-CD2 3.99Å; L223-F312 HydrophobicContact CD1-CE2 4.29Å; L308-F312 HydrophobicContact CD1-CE2 3.88Å; L308-F312 HydrophobicContact CD1-CZ 4.21Å; L308-F312 HydrophobicContact CD2-CE2 3.83Å; L308-F312 HydrophobicContact CG-CD2 3.93Å; L308-F312 HydrophobicContact CG-CE2 3.51Å; L308-F312 HydrophobicContact CG-CZ 4.33Å; L308-F312 WeakPolarHBondContact O-CD2 3.1Å; L308-F312 PolarHBondContact O-N 3.33Å; G309-F312 PolarHBondContact O-N 3.28Å; V310-F312 VanDerWaalsContact C-N 3.33Å; V310-F312 PolarHBondContact O-N 3.1Å; F312-A316 WeakPolarHBondContact O-CB 3.11Å; F312-A316 PolarHBondContact O-N 2.9Å; F312-Y376 HydrophobicContact CB-CE2 4.4Å; F312-Y376 AromaticContact CD1-CD2 3.73Å; F312-Y376 HydrophobicContact CD1-CD2 3.73Å; F312-Y376 AromaticContact CD1-CE2 3.54Å; F312-Y376 HydrophobicContact CD1-CE2 3.54Å; F312-Y376 AromaticContact CE1-CD2 3.89Å; F312-Y376 HydrophobicContact CE1-CD2 3.89Å; F312-Y376 HydrophobicContact CE1-CE2 4.17Å; F312-Y376 HydrophobicContact CG-CE2 4.27Å; F312-Y376 PolarHBondContact O-OH 3.47Å
313	I	94.3	Very high	93.2	Very high	42 Å²	42	54.2 Å²	54.2	22%	0.215	29%	0.285	C	S	.	.	H	α-helix	trans	-66.8	-45.3	170	-64.9	-177.4	0	0	0	110.3	P220 L221 I224 G309 V310 F311 V315 A316 L317	P220-I313 HydrophobicContact CB-CD1 4.22Å; P220-I313 HydrophobicContact CB-CG1 3.48Å; P220-I313 VanDerWaalsContact CB-CG1 3.48Å; P220-I313 HydrophobicContact CG-CG1 3.73Å; L221-I313 HydrophobicContact CD2-CD1 4Å; L221-I313 HydrophobicContact CG-CD1 4.43Å; I224-I313 HydrophobicContact CD1-CD1 3.54Å; I224-I313 HydrophobicContact CD1-CG1 4.46Å; G309-I313 WeakPolarHBondContact O-CG1 3.49Å; G309-I313 PolarHBondContact O-N 3.1Å; G309-I313 VanDerWaalsContact O-N 3.08Å; V310-I313 PolarHBondContact O-N 3.02Å; V310-I313 VanDerWaalsContact O-N 3.15Å; F311-I313 VanDerWaalsContact C-N 3.33Å; F311-I313 PolarHBondContact O-N 3.27Å; I313-V315 VanDerWaalsContact C-N 3.3Å; I313-V315 PolarHBondContact O-N 3.24Å; I313-A316 WeakPolarHBondContact O-CB 3.35Å; I313-A316 PolarHBondContact O-N 3.33Å; I313-A316 VanDerWaalsContact O-N 3.15Å; I313-L317 HydrophobicContact CG2-CD1 4.01Å; I313-L317 HydrophobicContact CG2-CG 4.28Å; I313-L317 WeakPolarHBondContact O-CG 3.42Å; I313-L317 PolarHBondContact O-N 3.2Å
314	L	94.8	Very high	93.5	Very high	107 Å²	107	55 Å²	55	56%	0.56	28%	0.281	S	S	*	.	H	α-helix	trans	-60	-42.4	178.5	-66.8	174.2	0	0	0	111.4	V310 F311 L317 L318	V310-L314 HydrophobicContact CG1-CD1 4.42Å; V310-L314 WeakPolarHBondContact O-CG 3.3Å; V310-L314 PolarHBondContact O-N 3.45Å; F311-L314 WeakPolarHBondContact O-CB 3.43Å; F311-L314 PolarHBondContact O-N 3.36Å; F311-L314 VanDerWaalsContact O-N 3.17Å; L314-L317 PolarHBondContact O-N 2.99Å; L314-L318 WeakPolarHBondContact O-CB 3.34Å; L314-L318 PolarHBondContact O-N 3.22Å
315	V	94.3	Very high	93.7	Very high	27 Å²	27	52.7 Å²	52.7	16%	0.164	27%	0.265	C	S	.	.	H	α-helix	trans	-62.7	-43.7	174.2	173	0	0	0	0	111.5	F311 I313 L317 L318 F319 Y376	F311-V315 HydrophobicContact CD1-CG2 4.35Å; F311-V315 HydrophobicContact CE1-CG2 3.9Å; F311-V315 HydrophobicContact CE2-CG2 4.17Å; F311-V315 HydrophobicContact CZ-CG2 3.79Å; F311-V315 WeakPolarHBondContact O-CG2 3.33Å; F311-V315 PolarHBondContact O-N 3.42Å; I313-V315 VanDerWaalsContact C-N 3.3Å; I313-V315 PolarHBondContact O-N 3.24Å; V315-L317 VanDerWaalsContact C-N 3.32Å; V315-L317 PolarHBondContact O-N 2.84Å; V315-L318 WeakPolarHBondContact O-CB 3.37Å; V315-L318 PolarHBondContact O-N 3.35Å; V315-F319 HydrophobicContact CG1-CD2 4.01Å; V315-F319 HydrophobicContact CG1-CE2 3.37Å; V315-F319 HydrophobicContact CG1-CZ 3.73Å; V315-F319 WeakPolarHBondContact O-CD2 3.44Å; V315-F319 PolarHBondContact O-N 3.47Å; V315-Y376 HydrophobicContact CG1-CD2 4.34Å; V315-Y376 HydrophobicContact CG1-CE1 4.32Å; V315-Y376 HydrophobicContact CG1-CE2 4.11Å
316	A	95	Very high	93.7	Very high	1 Å²	1	49 Å²	49	1%	0.008	25%	0.25	C	S	.	.	H	α-helix	trans	-61.1	-41.3	176.7	0	0	0	0	0	112.2	M216 F312 I313 F319 T320 Y376 F504	M216-A316 HydrophobicContact CB-CB 4.45Å; F312-A316 WeakPolarHBondContact O-CB 3.11Å; F312-A316 PolarHBondContact O-N 2.9Å; I313-A316 WeakPolarHBondContact O-CB 3.35Å; I313-A316 PolarHBondContact O-N 3.33Å; I313-A316 VanDerWaalsContact O-N 3.15Å; A316-F319 PolarHBondContact O-N 2.83Å; A316-T320 WeakPolarHBondContact O-CB 3.45Å; A316-T320 PolarHBondContact O-N 3.1Å; A316-T320 PolarHBondContact O-OG1 3.05Å; A316-Y376 WeakPolarHBondContact CB-OH 3.2Å; A316-F504 HydrophobicContact CB-CE2 3.89Å; A316-F504 HydrophobicContact CB-CZ 3.86Å
317	L	94.3	Very high	93.6	Very high	72 Å²	72	46.1 Å²	46.1	38%	0.377	24%	0.235	S	C	.	.	H	α-helix	trans	-66.1	-41.9	176.1	-70.1	174.7	0	0	0	111.4	I313 L314 V315 F319 T320 I321 F504	I313-L317 HydrophobicContact CG2-CD1 4.01Å; I313-L317 HydrophobicContact CG2-CG 4.28Å; I313-L317 WeakPolarHBondContact O-CG 3.42Å; I313-L317 PolarHBondContact O-N 3.2Å; L314-L317 PolarHBondContact O-N 2.99Å; V315-L317 VanDerWaalsContact C-N 3.32Å; V315-L317 PolarHBondContact O-N 2.84Å; L317-F319 VanDerWaalsContact C-N 3.35Å; L317-F319 PolarHBondContact O-N 3.42Å; L317-T320 PolarHBondContact O-N 2.86Å; L317-I321 WeakPolarHBondContact O-CB 3.47Å; L317-I321 VanDerWaalsContact O-CG1 3.28Å; L317-I321 WeakPolarHBondContact O-CG1 3.29Å; L317-I321 PolarHBondContact O-N 3.29Å; L317-F504 HydrophobicContact CD2-CE1 4.48Å
318	L	94.1	Very high	93.5	Very high	58 Å²	58	43.4 Å²	43.4	30%	0.304	22%	0.221	S	C	.	.	H	α-helix	trans	-57.1	-47.4	174.9	178.6	66.3	0	0	0	111.3	L314 V315 I321 S322 P351	L314-L318 WeakPolarHBondContact O-CB 3.34Å; L314-L318 PolarHBondContact O-N 3.22Å; V315-L318 WeakPolarHBondContact O-CB 3.37Å; V315-L318 PolarHBondContact O-N 3.35Å; L318-I321 PolarHBondContact O-N 3.37Å; L318-S322 VanDerWaalsContact O-CB 3.29Å; L318-S322 WeakPolarHBondContact O-CB 3.12Å; L318-S322 PolarHBondContact O-N 3.34Å; L318-S322 PolarHBondContact O-OG 3.01Å; L318-P351 HydrophobicContact CD1-CB 4.15Å; L318-P351 HydrophobicContact CD1-CG 4.03Å
319	F	94.3	Very high	93.3	Very high	6 Å²	6	40 Å²	40	3%	0.026	20%	0.203	C	C	.	.	H	α-helix	trans	-64.6	-40.9	176.8	-65.7	-33.5	0	0	0	112.6	V315 A316 L317 S322 L323 L352 I373 Y376 F377 L431	V315-F319 HydrophobicContact CG1-CD2 4.01Å; V315-F319 HydrophobicContact CG1-CE2 3.37Å; V315-F319 HydrophobicContact CG1-CZ 3.73Å; V315-F319 WeakPolarHBondContact O-CD2 3.44Å; V315-F319 PolarHBondContact O-N 3.47Å; A316-F319 PolarHBondContact O-N 2.83Å; L317-F319 VanDerWaalsContact C-N 3.35Å; L317-F319 PolarHBondContact O-N 3.42Å; F319-S322 PolarHBondContact O-N 3.03Å; F319-L323 WeakPolarHBondContact O-CB 3.14Å; F319-L323 WeakPolarHBondContact O-CG 3.47Å; F319-L323 PolarHBondContact O-N 2.81Å; F319-L352 HydrophobicContact CD1-CD2 3.83Å; F319-L352 HydrophobicContact CE1-CD1 4.31Å; F319-L352 HydrophobicContact CE1-CD2 3.83Å; F319-I373 HydrophobicContact CE1-CD1 4.35Å; F319-I373 HydrophobicContact CE1-CG1 4.1Å; F319-I373 HydrophobicContact CE1-CG2 4.2Å; F319-I373 HydrophobicContact CZ-CB 4.32Å; F319-I373 HydrophobicContact CZ-CG1 3.84Å; F319-I373 HydrophobicContact CZ-CG2 3.91Å; F319-Y376 HydrophobicContact CD2-CD1 4.12Å; F319-Y376 AromaticContact CD2-CE1 3.77Å; F319-Y376 HydrophobicContact CD2-CE1 3.77Å; F319-Y376 AromaticContact CE2-CD1 3.47Å; F319-Y376 HydrophobicContact CE2-CD1 3.47Å; F319-Y376 VanDerWaalsContact CE2-CD1 3.47Å; F319-Y376 AromaticContact CE2-CE1 3.55Å; F319-Y376 HydrophobicContact CE2-CE1 3.55Å; F319-Y376 HydrophobicContact CE2-CG 4.28Å; F319-F377 HydrophobicContact CD2-CE1 4.36Å; F319-F377 HydrophobicContact CD2-CE2 4.48Å; F319-F377 AromaticContact CD2-CZ 3.87Å; F319-F377 HydrophobicContact CD2-CZ 3.87Å; F319-F377 HydrophobicContact CE2-CE2 4.37Å; F319-F377 HydrophobicContact CE2-CZ 4.18Å; F319-F377 HydrophobicContact CG-CZ 4.22Å; F319-L431 HydrophobicContact CB-CD2 4.11Å; F319-L431 HydrophobicContact CD1-CD1 4.36Å; F319-L431 HydrophobicContact CD1-CD2 3.96Å; F319-L431 HydrophobicContact CG-CD2 4.36Å
320	T	94.4	Very high	92.9	Very high	14 Å²	14	40.1 Å²	40.1	9%	0.086	20%	0.204	C	C	.	.	H	α-helix	trans	-64.2	-45	179.1	-54.9	0	0	0	0	111.3	A316 L317 F324 I501 F504	A316-T320 WeakPolarHBondContact O-CB 3.45Å; A316-T320 PolarHBondContact O-N 3.1Å; A316-T320 PolarHBondContact O-OG1 3.05Å; L317-T320 PolarHBondContact O-N 2.86Å; T320-F324 VanDerWaalsContact O-CB 3.28Å; T320-F324 WeakPolarHBondContact O-CB 3.4Å; T320-F324 PolarHBondContact O-N 2.91Å; T320-I501 HydrophobicContact CG2-CG1 4.41Å; T320-I501 HydrophobicContact CG2-CG2 4.07Å; T320-F504 HydrophobicContact CG2-CD1 4Å; T320-F504 HydrophobicContact CG2-CE1 4.24Å; T320-F504 WeakPolarHBondContact OG1-CD1 3.29Å; T320-F504 VanDerWaalsContact OG1-CE1 3.32Å; T320-F504 WeakPolarHBondContact OG1-CE1 3.34Å
321	I	94.2	Very high	92.5	Very high	92 Å²	92	39.1 Å²	39.1	47%	0.472	20%	0.204	S	C	.	.	H	α-helix	trans	-64.8	-44.1	176.8	-68.2	166.5	0	0	0	110.5	L317 L318 F324 I325	L317-I321 WeakPolarHBondContact O-CB 3.47Å; L317-I321 VanDerWaalsContact O-CG1 3.28Å; L317-I321 WeakPolarHBondContact O-CG1 3.29Å; L317-I321 PolarHBondContact O-N 3.29Å; L318-I321 PolarHBondContact O-N 3.37Å; I321-F324 PolarHBondContact O-N 3.43Å; I321-I325 HydrophobicContact CG2-CD1 3.72Å; I321-I325 HydrophobicContact CG2-CG1 4.38Å; I321-I325 VanDerWaalsContact O-CG1 3.32Å; I321-I325 WeakPolarHBondContact O-CG1 3.13Å; I321-I325 PolarHBondContact O-N 3.28Å
322	S	93.9	Very high	92	Very high	0 Å²	0	39 Å²	39	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-61.7	-47.7	178.8	-56.1	0	0	0	0	111.4	L318 F319 F324 I325 S326 N350 L352	L318-S322 VanDerWaalsContact O-CB 3.29Å; L318-S322 WeakPolarHBondContact O-CB 3.12Å; L318-S322 PolarHBondContact O-N 3.34Å; L318-S322 PolarHBondContact O-OG 3.01Å; F319-S322 PolarHBondContact O-N 3.03Å; S322-F324 VanDerWaalsContact C-N 3.35Å; S322-F324 PolarHBondContact O-N 3.02Å; S322-I325 PolarHBondContact O-N 2.93Å; S322-S326 WeakPolarHBondContact O-CB 3.47Å; S322-S326 PolarHBondContact O-N 3.13Å; S322-N350 WeakPolarHBondContact CB-OD1 3.36Å; S322-N350 PolarHBondContact O-ND2 3.03Å; S322-N350 PolarHBondContact OG-OD1 3.43Å; S322-L352 WeakPolarHBondContact OG-CB 3.28Å
323	L	93.4	Very high	91.3	Very high	0 Å²	0	41.8 Å²	41.8	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-61.7	-42	174.5	-76.9	176.6	0	0	0	111.8	F319 S326 N327 L431 F500 I501	F319-L323 WeakPolarHBondContact O-CB 3.14Å; F319-L323 WeakPolarHBondContact O-CG 3.47Å; F319-L323 PolarHBondContact O-N 2.81Å; L323-S326 PolarHBondContact O-N 3.12Å; L323-N327 WeakPolarHBondContact O-CB 3.26Å; L323-N327 PolarHBondContact O-N 3.44Å; L323-N327 PolarHBondContact O-ND2 3.43Å; L323-L431 HydrophobicContact CD1-CD2 4.33Å; L323-L431 HydrophobicContact CD2-CD2 3.87Å; L323-L431 HydrophobicContact CD2-CG 3.81Å; L323-L431 HydrophobicContact CG-CD2 3.59Å; L323-L431 HydrophobicContact CG-CG 4.08Å; L323-F500 HydrophobicContact CD1-CD1 3.88Å; L323-F500 HydrophobicContact CD1-CE1 3.93Å; L323-I501 HydrophobicContact CB-CD1 4.22Å
324	F	94.1	Very high	90.4	Very high	90 Å²	90	40.9 Å²	40.9	40%	0.395	22%	0.218	S	C	.	.	H	α-helix	trans	-61	-48.8	178.4	-179.9	-93.5	0	0	0	111.4	T320 I321 S322 S326 N327 L328 W498 I501	T320-F324 VanDerWaalsContact O-CB 3.28Å; T320-F324 WeakPolarHBondContact O-CB 3.4Å; T320-F324 PolarHBondContact O-N 2.91Å; I321-F324 PolarHBondContact O-N 3.43Å; S322-F324 VanDerWaalsContact C-N 3.35Å; S322-F324 PolarHBondContact O-N 3.02Å; F324-S326 PolarHBondContact O-N 3.31Å; F324-N327 PolarHBondContact O-N 2.93Å; F324-L328 HydrophobicContact CE1-CD2 4.37Å; F324-L328 WeakPolarHBondContact O-CB 3.36Å; F324-L328 PolarHBondContact O-N 2.84Å; F324-W498 AromaticContact CD2-CH2 3.79Å; F324-W498 HydrophobicContact CD2-CH2 3.79Å; F324-W498 AromaticContact CD2-CZ3 3.7Å; F324-W498 HydrophobicContact CD2-CZ3 3.7Å; F324-W498 AromaticContact CE2-CH2 3.57Å; F324-W498 HydrophobicContact CE2-CH2 3.57Å; F324-W498 AromaticContact CE2-CZ3 3.63Å; F324-W498 HydrophobicContact CE2-CZ3 3.63Å; F324-W498 HydrophobicContact CZ-CH2 4.45Å; F324-I501 HydrophobicContact CB-CD1 4.22Å
325	I	92.4	Very high	89.1	Confident	40 Å²	40	38.4 Å²	38.4	21%	0.205	21%	0.213	C	C	.	.	H	α-helix	trans	-61.1	-46.5	178.1	-67.3	168.4	0	0	0	110.5	I321 S322 N327 L328 D329 L348	I321-I325 HydrophobicContact CG2-CD1 3.72Å; I321-I325 HydrophobicContact CG2-CG1 4.38Å; I321-I325 VanDerWaalsContact O-CG1 3.32Å; I321-I325 WeakPolarHBondContact O-CG1 3.13Å; I321-I325 PolarHBondContact O-N 3.28Å; S322-I325 PolarHBondContact O-N 2.93Å; I325-N327 PolarHBondContact O-N 3.09Å; I325-L328 PolarHBondContact O-N 2.96Å; I325-D329 PolarHBondContact O-N 2.77Å; I325-L348 HydrophobicContact CG2-CB 3.89Å
326	S	89.6	Confident	88.1	Confident	5 Å²	5	38.2 Å²	38.2	4%	0.035	22%	0.217	C	C	.	.	H	α-helix	trans	-65.5	-37.5	179.6	-78.8	0	0	0	0	113.3	S322 L323 F324 D329 K330 N350 S430	S322-S326 WeakPolarHBondContact O-CB 3.47Å; S322-S326 PolarHBondContact O-N 3.13Å; L323-S326 PolarHBondContact O-N 3.12Å; F324-S326 PolarHBondContact O-N 3.31Å; S326-D329 PolarHBondContact O-N 2.98Å; S326-K330 WeakPolarHBondContact O-CG 3.48Å; S326-K330 PolarHBondContact O-N 3.46Å; S326-K330 VanDerWaalsContact O-N 3.07Å; S326-N350 PolarHBondContact OG-ND2 3.19Å; S326-S430 WeakPolarHBondContact CB-O 3.23Å; S326-S430 PolarHBondContact OG-O 3.44Å
327	N	90.4	Very high	87.1	Confident	0 Å²	0	43 Å²	43	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-73.1	-32.7	175	-68.6	-54.5	0	0	0	112.1	L323 F324 I325 D329 K330 A331 Y494 N497 W498	L323-N327 WeakPolarHBondContact O-CB 3.26Å; L323-N327 PolarHBondContact O-N 3.44Å; L323-N327 PolarHBondContact O-ND2 3.43Å; F324-N327 PolarHBondContact O-N 2.93Å; I325-N327 PolarHBondContact O-N 3.09Å; N327-D329 VanDerWaalsContact C-N 3.35Å; N327-K330 WeakPolarHBondContact O-CB 3.07Å; N327-K330 PolarHBondContact O-N 2.9Å; N327-A331 WeakPolarHBondContact O-CB 3.48Å; N327-A331 PolarHBondContact O-N 2.64Å; N327-Y494 HydrophobicContact CB-CE2 3.99Å; N327-N497 WeakPolarHBondContact ND2-CB 3.1Å; N327-N497 PolarHBondContact OD1-ND2 3.2Å; N327-N497 VanDerWaalsContact OD1-ND2 3.12Å; N327-W498 HydrophobicContact CB-CZ2 4.05Å
328	L	90.1	Very high	85.9	Confident	63 Å²	63	42.6 Å²	42.6	33%	0.33	24%	0.244	S	C	.	.	H	α-helix	trans	-63.9	-42.3	172.1	-177.1	64.9	0	0	0	110.9	F324 I325 K330 A331 L332 L348	F324-L328 HydrophobicContact CE1-CD2 4.37Å; F324-L328 WeakPolarHBondContact O-CB 3.36Å; F324-L328 PolarHBondContact O-N 2.84Å; I325-L328 PolarHBondContact O-N 2.96Å; L328-K330 VanDerWaalsContact C-N 3.32Å; L328-K330 PolarHBondContact O-N 2.84Å; L328-A331 WeakPolarHBondContact O-CB 3.24Å; L328-A331 PolarHBondContact O-N 3.24Å; L328-A331 VanDerWaalsContact O-N 3.15Å; L328-L332 HydrophobicContact CD1-CD1 4.12Å; L328-L332 HydrophobicContact CD1-CG 4.36Å; L328-L332 HydrophobicContact CG-CD1 4.01Å; L328-L332 WeakPolarHBondContact O-CG 3.3Å; L328-L332 PolarHBondContact O-N 3.07Å; L328-L348 HydrophobicContact CD2-CD1 4.29Å; L328-L348 HydrophobicContact CG-CD1 4.32Å
329	D	87.4	Confident	84.7	Confident	4 Å²	4	41.2 Å²	41.2	2%	0.021	24%	0.235	C	C	.	.	H	α-helix	trans	-61.1	-42.7	175.3	-158.7	25.9	0	0	0	111.1	I325 S326 N327 A331 L332 H333 I343 N347 L348	I325-D329 PolarHBondContact O-N 2.77Å; S326-D329 PolarHBondContact O-N 2.98Å; N327-D329 VanDerWaalsContact C-N 3.35Å; D329-A331 VanDerWaalsContact C-N 3.31Å; D329-A331 PolarHBondContact O-N 3.48Å; D329-L332 PolarHBondContact O-N 2.94Å; D329-H333 PolarHBondContact O-N 3.15Å; D329-H333 IonicContact OD1-CE1 3.15Å; D329-H333 IonicContact OD1-CG 2.87Å; D329-H333 IonicContact OD1-ND1 3.13Å; D329-H333 PolarHBondContact OD1-ND1 3.4Å; D329-I343 HydrophobicContact CB-CD1 4.15Å; D329-N347 PolarHBondContact OD2-N 3.42Å; D329-L348 HydrophobicContact CB-CB 4.24Å; D329-L348 HydrophobicContact CB-CD1 4.01Å; D329-L348 HydrophobicContact CB-CG 4.28Å
330	K	85.3	Confident	83.5	Confident	4 Å²	4	41.1 Å²	41.1	2%	0.017	24%	0.235	C	C	.	.	H	α-helix	trans	-59.3	-42.5	173.7	-74.1	-178.7	179.8	-179.3	0	111.4	S326 N327 L328 L332 S334 F341 I343 Y494	S326-K330 WeakPolarHBondContact O-CG 3.48Å; S326-K330 PolarHBondContact O-N 3.46Å; S326-K330 VanDerWaalsContact O-N 3.07Å; N327-K330 WeakPolarHBondContact O-CB 3.07Å; N327-K330 PolarHBondContact O-N 2.9Å; L328-K330 VanDerWaalsContact C-N 3.32Å; L328-K330 PolarHBondContact O-N 2.84Å; K330-L332 VanDerWaalsContact C-N 3.33Å; K330-L332 PolarHBondContact O-N 3.03Å; K330-S334 WeakPolarHBondContact O-CB 3.43Å; K330-S334 PolarHBondContact O-N 3.32Å; K330-S334 PolarHBondContact O-OG 3.36Å; K330-F341 HydrophobicContact CB-CB 4.36Å; K330-I343 HydrophobicContact CB-CD1 4.05Å; K330-I343 HydrophobicContact CB-CG1 4.32Å; K330-I343 HydrophobicContact CD-CD1 4.24Å; K330-I343 HydrophobicContact CG-CD1 3.15Å; K330-I343 HydrophobicContact CG-CG1 3.6Å; K330-Y494 HydrophobicContact CB-CD2 4.09Å; K330-Y494 HydrophobicContact CB-CE2 3.82Å; K330-Y494 HydrophobicContact CD-CD2 3.97Å; K330-Y494 HydrophobicContact CD-CE2 4.5Å
331	A	85.9	Confident	82.6	Confident	50 Å²	50	41.3 Å²	41.3	41%	0.413	24%	0.235	S	C	.	.	H	α-helix	trans	-66.7	-34.8	-178.5	0	0	0	0	0	112.7	N327 L328 D329	N327-A331 WeakPolarHBondContact O-CB 3.48Å; N327-A331 PolarHBondContact O-N 2.64Å; L328-A331 WeakPolarHBondContact O-CB 3.24Å; L328-A331 PolarHBondContact O-N 3.24Å; L328-A331 VanDerWaalsContact O-N 3.15Å; D329-A331 VanDerWaalsContact C-N 3.31Å; D329-A331 PolarHBondContact O-N 3.48Å
332	L	84.3	Confident	81.5	Confident	111 Å²	111	37.2 Å²	37.2	58%	0.581	21%	0.214	S	C	*	.	H	α-helix	trans	-90	-35	-174.2	-65.8	173.9	0	0	0	113.5	L328 D329 K330	L328-L332 HydrophobicContact CD1-CD1 4.12Å; L328-L332 HydrophobicContact CD1-CG 4.36Å; L328-L332 HydrophobicContact CG-CD1 4.01Å; L328-L332 WeakPolarHBondContact O-CG 3.3Å; L328-L332 PolarHBondContact O-N 3.07Å; D329-L332 PolarHBondContact O-N 2.94Å; K330-L332 VanDerWaalsContact C-N 3.33Å; K330-L332 PolarHBondContact O-N 3.03Å
333	H	80.6	Confident	80.2	Confident	91 Å²	91	37.6 Å²	37.6	42%	0.421	22%	0.216	S	C	.	.	H	α-helix	trans	-123.3	0.8	-166.6	-56	115.5	0	0	0	115	D329 N347	D329-H333 PolarHBondContact O-N 3.15Å; D329-H333 IonicContact OD1-CE1 3.15Å; D329-H333 IonicContact OD1-CG 2.87Å; D329-H333 IonicContact OD1-ND1 3.13Å; D329-H333 PolarHBondContact OD1-ND1 3.4Å; H333-N347 PolarHBondContact CD2-ND2 3.36Å
334	S	76.6	Confident	78.6	Confident	24 Å²	24	39.1 Å²	39.1	17%	0.168	22%	0.223	C	C	.	.	S	Bend	trans	-82	164	176.3	74	0	0	0	0	112.8	K330 G336 F341 I342	K330-S334 WeakPolarHBondContact O-CB 3.43Å; K330-S334 PolarHBondContact O-N 3.32Å; K330-S334 PolarHBondContact O-OG 3.36Å; S334-G336 PolarHBondContact O-N 3.39Å; S334-G336 PolarHBondContact OG-N 3.05Å; S334-F341 VanDerWaalsContact OG-CD1 3.28Å; S334-F341 WeakPolarHBondContact OG-CD1 3.36Å; S334-I342 WeakPolarHBondContact CB-O 3.37Å
335	A	67.2	Low	77.1	Confident	55 Å²	55	35.9 Å²	35.9	46%	0.455	22%	0.215	S	C	.	.			trans	-66.6	1.9	172.9	0	0	0	0	0	114.2	Y339 F344	A335-Y339 HydrophobicContact CB-CD2 3.76Å; A335-Y339 HydrophobicContact CB-CG 3.9Å; A335-Y339 VanDerWaalsContact O-CD2 3.3Å; A335-Y339 WeakPolarHBondContact O-CD2 3.32Å; A335-F344 HydrophobicContact CB-CE2 4.33Å
336	G	71.8	Confident	75.9	Confident	23 Å²	23	36.6 Å²	36.6	24%	0.237	22%	0.222	C	C	.	.			trans	92.4	-167.7	175.2	0	0	0	0	0	115.1	S334 S338 Y339 F341	S334-G336 PolarHBondContact O-N 3.39Å; S334-G336 PolarHBondContact OG-N 3.05Å; G336-S338 PolarHBondContact O-N 2.99Å; G336-Y339 PolarHBondContact O-N 3.26Å; G336-F341 PolarHBondContact O-N 3.13Å
337	I	75.2	Confident	75.1	Confident	102 Å²	102	41.6 Å²	41.6	52%	0.523	25%	0.248	S	C	.	.	G	3₁₀ helix	trans	-63.8	-39.3	-170.6	-63.5	168.4	0	0	0	112.3	Y339 G340 F341 W487 T491	I337-Y339 PolarHBondContact O-N 3Å; I337-Y339 VanDerWaalsContact O-N 3.15Å; I337-G340 PolarHBondContact O-N 3.35Å; I337-F341 HydrophobicContact CB-CE2 4.24Å; I337-F341 HydrophobicContact CB-CZ 4.39Å; I337-F341 HydrophobicContact CG1-CE1 4.49Å; I337-F341 HydrophobicContact CG1-CE2 3.67Å; I337-F341 HydrophobicContact CG1-CZ 3.45Å; I337-F341 VanDerWaalsContact CG1-CZ 3.45Å; I337-W487 WeakPolarHBondContact O-CZ3 3.49Å; I337-T491 HydrophobicContact CG2-CG2 4.07Å; I337-T491 PolarHBondContact O-OG1 3.5Å; I337-T491 VanDerWaalsContact O-OG1 3.11Å
338	S	68.9	Low	74.7	Confident	63 Å²	63	44.5 Å²	44.5	44%	0.441	26%	0.263	S	S	.	.	G	3₁₀ helix	trans	-67.1	-13	-176.6	-52.8	0	0	0	0	113.7	G336 W487	G336-S338 PolarHBondContact O-N 2.99Å; S338-W487 WeakPolarHBondContact O-CZ3 3.41Å
339	Y	68.3	Low	74.4	Confident	29 Å²	29	46.4 Å²	46.4	11%	0.114	28%	0.277	C	S	.	.	G	3₁₀ helix	trans	-120.7	15.1	-174.9	-62.8	-82.8	0	0	0	113	P166 G168 W174 A335 G336 I337 F341 I342	P166-Y339 HydrophobicContact CG-CD1 4.17Å; P166-Y339 HydrophobicContact CG-CE1 3.71Å; G168-Y339 PolarHBondContact O-OH 2.98Å; W174-Y339 HydrophobicContact CD2-CD1 4.09Å; W174-Y339 HydrophobicContact CD2-CE1 4.03Å; W174-Y339 AromaticContact CE3-CD1 3.76Å; W174-Y339 HydrophobicContact CE3-CD1 3.76Å; W174-Y339 HydrophobicContact CE3-CE1 4.18Å; W174-Y339 HydrophobicContact CG-CE1 4.5Å; W174-Y339 AromaticContact CH2-CD1 3.97Å; W174-Y339 HydrophobicContact CH2-CD1 3.97Å; W174-Y339 HydrophobicContact CZ2-CD1 4.28Å; W174-Y339 HydrophobicContact CZ2-CE1 4.45Å; W174-Y339 AromaticContact CZ3-CD1 3.71Å; W174-Y339 HydrophobicContact CZ3-CD1 3.71Å; W174-Y339 HydrophobicContact CZ3-CE1 4.45Å; A335-Y339 HydrophobicContact CB-CD2 3.76Å; A335-Y339 HydrophobicContact CB-CG 3.9Å; A335-Y339 VanDerWaalsContact O-CD2 3.3Å; A335-Y339 WeakPolarHBondContact O-CD2 3.32Å; G336-Y339 PolarHBondContact O-N 3.26Å; I337-Y339 PolarHBondContact O-N 3Å; I337-Y339 VanDerWaalsContact O-N 3.15Å; Y339-F341 PolarHBondContact O-N 3.45Å; Y339-I342 WeakPolarHBondContact O-CG1 3.32Å
340	G	69.8	Low	74.5	Confident	3 Å²	3	46.5 Å²	46.5	3%	0.031	28%	0.278	C	S	.	.	T	Hydrogen-bonded Turn	trans	80.5	10.6	173.2	0	0	0	0	0	115.8	I337 I342 W487 S490 T491	I337-G340 PolarHBondContact O-N 3.35Å; G340-I342 PolarHBondContact O-N 2.9Å; G340-W487 VanDerWaalsContact CA-O 3.26Å; G340-W487 WeakPolarHBondContact CA-O 3.41Å; G340-S490 VanDerWaalsContact O-CB 3.29Å; G340-S490 WeakPolarHBondContact O-CB 3.47Å; G340-T491 VanDerWaalsContact CA-OG1 3.26Å; G340-T491 WeakPolarHBondContact CA-OG1 3.38Å
341	F	75.6	Confident	74.8	Confident	19 Å²	19	48.7 Å²	48.7	8%	0.083	29%	0.293	C	S	.	.	T	Hydrogen-bonded Turn	trans	52.7	36.6	-171.8	-67	-88.2	0	0	0	113.4	K330 S334 G336 I337 Y339 T491 Y494 F495	K330-F341 HydrophobicContact CB-CB 4.36Å; S334-F341 VanDerWaalsContact OG-CD1 3.28Å; S334-F341 WeakPolarHBondContact OG-CD1 3.36Å; G336-F341 PolarHBondContact O-N 3.13Å; I337-F341 HydrophobicContact CB-CE2 4.24Å; I337-F341 HydrophobicContact CB-CZ 4.39Å; I337-F341 HydrophobicContact CG1-CE1 4.49Å; I337-F341 HydrophobicContact CG1-CE2 3.67Å; I337-F341 HydrophobicContact CG1-CZ 3.45Å; I337-F341 VanDerWaalsContact CG1-CZ 3.45Å; Y339-F341 PolarHBondContact O-N 3.45Å; F341-T491 HydrophobicContact CD2-CG2 4.38Å; F341-T491 HydrophobicContact CE2-CG2 4.21Å; F341-Y494 HydrophobicContact CB-CD2 4.25Å; F341-Y494 HydrophobicContact CB-CG 4.19Å; F341-Y494 HydrophobicContact CD1-CD1 4.34Å; F341-Y494 HydrophobicContact CD1-CD2 4.5Å; F341-Y494 HydrophobicContact CD1-CE1 4.22Å; F341-Y494 HydrophobicContact CD1-CE2 4.38Å; F341-Y494 HydrophobicContact CD1-CG 4.48Å; F341-Y494 AromaticContact CD2-CD1 3.63Å; F341-Y494 HydrophobicContact CD2-CD1 3.63Å; F341-Y494 HydrophobicContact CD2-CE1 4.2Å; F341-Y494 AromaticContact CD2-CG 3.84Å; F341-Y494 HydrophobicContact CD2-CG 3.84Å; F341-Y494 HydrophobicContact CE1-CD1 4.34Å; F341-Y494 AromaticContact CE1-CE1 3.93Å; F341-Y494 HydrophobicContact CE1-CE1 3.93Å; F341-Y494 AromaticContact CE2-CD1 3.59Å; F341-Y494 HydrophobicContact CE2-CD1 3.59Å; F341-Y494 AromaticContact CE2-CE1 3.88Å; F341-Y494 HydrophobicContact CE2-CE1 3.88Å; F341-Y494 HydrophobicContact CE2-CG 4.28Å; F341-Y494 HydrophobicContact CG-CD1 4.01Å; F341-Y494 HydrophobicContact CG-CD2 4.22Å; F341-Y494 HydrophobicContact CG-CE1 4.35Å; F341-Y494 AromaticContact CG-CG 3.94Å; F341-Y494 HydrophobicContact CG-CG 3.94Å; F341-Y494 AromaticContact CZ-CD1 3.96Å; F341-Y494 HydrophobicContact CZ-CD1 3.96Å; F341-Y494 AromaticContact CZ-CE1 3.74Å; F341-Y494 HydrophobicContact CZ-CE1 3.74Å; F341-F495 HydrophobicContact CE2-CE2 4.29Å; F341-F495 HydrophobicContact CE2-CZ 4.37Å
342	I	70.2	Confident	74.9	Confident	5 Å²	5	46.5 Å²	46.5	3%	0.026	27%	0.274	C	S	.	.			trans	-70.6	131.2	174.9	-60	170.6	0	0	0	108.6	S334 Y339 G340 F344 Y480	S334-I342 WeakPolarHBondContact CB-O 3.37Å; Y339-I342 WeakPolarHBondContact O-CG1 3.32Å; G340-I342 PolarHBondContact O-N 2.9Å; I342-F344 HydrophobicContact CB-CE1 4.4Å; I342-F344 HydrophobicContact CB-CZ 4.25Å; I342-F344 HydrophobicContact CG2-CD1 4.32Å; I342-F344 HydrophobicContact CG2-CE1 3.67Å; I342-F344 HydrophobicContact CG2-CZ 4.02Å; I342-Y480 WeakPolarHBondContact CG2-OH 3.49Å
343	I	67.7	Low	75.2	Confident	8 Å²	8	41.4 Å²	41.4	4%	0.041	25%	0.247	C	C	.	.			trans	-96.4	132.9	174	-71.8	163.9	0	0	0	109	D329 K330 G345	D329-I343 HydrophobicContact CB-CD1 4.15Å; K330-I343 HydrophobicContact CB-CD1 4.05Å; K330-I343 HydrophobicContact CB-CG1 4.32Å; K330-I343 HydrophobicContact CD-CD1 4.24Å; K330-I343 HydrophobicContact CG-CD1 3.15Å; K330-I343 HydrophobicContact CG-CG1 3.6Å; I343-G345 VanDerWaalsContact CG2-C 3.43Å; I343-G345 WeakPolarHBondContact CG2-O 3.45Å
344	F	60	Low	75.6	Confident	32 Å²	32	41.7 Å²	41.7	14%	0.14	25%	0.249	C	C	.	.	S	Bend	trans	-95.2	-15.5	178.9	-63	-54.4	0	0	0	113.4	V177 A335 I342 A467	V177-F344 HydrophobicContact CG2-CD1 4.15Å; V177-F344 HydrophobicContact CG2-CE1 3.23Å; V177-F344 HydrophobicContact CG2-CZ 3.8Å; A335-F344 HydrophobicContact CB-CE2 4.33Å; I342-F344 HydrophobicContact CB-CE1 4.4Å; I342-F344 HydrophobicContact CB-CZ 4.25Å; I342-F344 HydrophobicContact CG2-CD1 4.32Å; I342-F344 HydrophobicContact CG2-CE1 3.67Å; I342-F344 HydrophobicContact CG2-CZ 4.02Å; F344-A467 HydrophobicContact CB-CB 3.65Å; F344-A467 HydrophobicContact CD1-CB 3.9Å; F344-A467 HydrophobicContact CG-CB 4.23Å; F344-A467 WeakPolarHBondContact O-CB 3.48Å; F344-A467 PolarHBondContact O-N 3.04Å
345	G	62.9	Low	76.2	Confident	23 Å²	23	44.1 Å²	44.1	24%	0.237	26%	0.259	C	S	.	.	S	Bend	trans	-164.6	142.8	170.4	0	0	0	0	0	111.1	I343 N347	I343-G345 VanDerWaalsContact CG2-C 3.43Å; I343-G345 WeakPolarHBondContact CG2-O 3.45Å; G345-N347 PolarHBondContact O-N 3.48Å
346	T	66.6	Low	77.2	Confident	55 Å²	55	41.5 Å²	41.5	34%	0.337	24%	0.238	S	C	.	.			trans	-79.4	115.7	178.6	53.7	0	0	0	0	110.5	P433 Q434	T346-P433 HydrophobicContact CG2-CG 4.02Å; T346-Q434 HydrophobicContact CG2-CB 3.99Å
347	N	71.9	Confident	78	Confident	109 Å²	109	41.7 Å²	41.7	58%	0.583	23%	0.233	S	C	*	.			trans	-95.1	-26	175.3	-74.2	-21.1	0	0	0	112.1	D329 H333 G345	D329-N347 PolarHBondContact OD2-N 3.42Å; H333-N347 PolarHBondContact CD2-ND2 3.36Å; G345-N347 PolarHBondContact O-N 3.48Å
348	L	81.6	Confident	78.6	Confident	61 Å²	61	40.3 Å²	40.3	32%	0.319	24%	0.237	S	C	.	.	S	Bend	trans	-101.7	131	177.1	-63	179.4	0	0	0	111.4	I325 L328 D329 N350	I325-L348 HydrophobicContact CG2-CB 3.89Å; L328-L348 HydrophobicContact CD2-CD1 4.29Å; L328-L348 HydrophobicContact CG-CD1 4.32Å; D329-L348 HydrophobicContact CB-CB 4.24Å; D329-L348 HydrophobicContact CB-CD1 4.01Å; D329-L348 HydrophobicContact CB-CG 4.28Å; L348-N350 PolarHBondContact O-N 2.87Å; L348-N350 VanDerWaalsContact O-N 3.17Å
349	T	83.9	Confident	79.3	Confident	104 Å²	104	39.7 Å²	39.7	64%	0.638	23%	0.229	S	C	*	.			trans	-70.1	111	178.5	-48.6	0	0	0	0	110.7	E354	T349-E354 HydrophobicContact CG2-CG 3.47Å; T349-E354 VanDerWaalsContact CG2-CG 3.47Å
350	N	89.7	Confident	80	Confident	6 Å²	6	39 Å²	39	3%	0.032	23%	0.227	C	C	.	.			trans	-90.5	125	173.2	174.2	-29.6	0	0	0	109.8	S322 S326 L348 L352 N353 E354 L431	S322-N350 WeakPolarHBondContact CB-OD1 3.36Å; S322-N350 PolarHBondContact O-ND2 3.03Å; S322-N350 PolarHBondContact OG-OD1 3.43Å; S326-N350 PolarHBondContact OG-ND2 3.19Å; L348-N350 PolarHBondContact O-N 2.87Å; L348-N350 VanDerWaalsContact O-N 3.17Å; N350-L352 PolarHBondContact O-N 3.45Å; N350-L352 PolarHBondContact OD1-N 2.86Å; N350-N353 HydrophobicContact CB-CB 3.85Å; N350-N353 WeakPolarHBondContact O-CB 3.28Å; N350-N353 PolarHBondContact O-N 3.31Å; N350-N353 PolarHBondContact OD1-N 2.98Å; N350-E354 PolarHBondContact O-N 3.45Å; N350-L431 PolarHBondContact ND2-O 3.44Å
351	P	91.6	Very high	80.4	Confident	50 Å²	50	43.8 Å²	43.8	33%	0.325	26%	0.257	S	S	.	.	H	α-helix	trans	-63.9	-36.1	-173.6	26.1	-34.7	0	0	0	113.5	L318 L355	L318-P351 HydrophobicContact CD1-CB 4.15Å; L318-P351 HydrophobicContact CD1-CG 4.03Å; P351-L355 WeakPolarHBondContact O-CB 3.46Å; P351-L355 PolarHBondContact O-N 3.08Å; P351-L355 VanDerWaalsContact O-N 3.09Å
352	L	89.8	Confident	80.6	Confident	4 Å²	4	47.1 Å²	47.1	2%	0.021	28%	0.278	C	S	.	.	H	α-helix	trans	-73	-36	178.1	-177	65.2	0	0	0	111.5	F319 S322 N350 L355 L356 I373 L431	F319-L352 HydrophobicContact CD1-CD2 3.83Å; F319-L352 HydrophobicContact CE1-CD1 4.31Å; F319-L352 HydrophobicContact CE1-CD2 3.83Å; S322-L352 WeakPolarHBondContact OG-CB 3.28Å; N350-L352 PolarHBondContact O-N 3.45Å; N350-L352 PolarHBondContact OD1-N 2.86Å; L352-L355 HydrophobicContact CD1-CD2 4.44Å; L352-L355 PolarHBondContact O-N 3.04Å; L352-L356 HydrophobicContact CD1-CD1 4.4Å; L352-L356 HydrophobicContact CG-CD1 4.08Å; L352-L356 WeakPolarHBondContact O-CG 3Å; L352-L356 PolarHBondContact O-N 3.45Å; L352-I373 HydrophobicContact CD1-CD1 4.18Å; L352-L431 HydrophobicContact CD2-CB 3.87Å; L352-L431 HydrophobicContact CD2-CD1 4.35Å; L352-L431 HydrophobicContact CD2-CD2 3.85Å; L352-L431 HydrophobicContact CD2-CG 4.25Å
353	N	90.1	Very high	80.5	Confident	4 Å²	4	50.5 Å²	50.5	2%	0.021	29%	0.293	C	S	.	.	H	α-helix	trans	-62.1	-49.2	175.4	-174.6	80.2	0	0	0	111.6	N350 L355 L356 L357 A432 Q434 Y435	N350-N353 HydrophobicContact CB-CB 3.85Å; N350-N353 WeakPolarHBondContact O-CB 3.28Å; N350-N353 PolarHBondContact O-N 3.31Å; N350-N353 PolarHBondContact OD1-N 2.98Å; N353-L355 VanDerWaalsContact C-N 3.33Å; N353-L355 PolarHBondContact O-N 3.1Å; N353-L356 PolarHBondContact O-N 3.13Å; N353-L357 WeakPolarHBondContact ND2-CD1 3.36Å; N353-L357 WeakPolarHBondContact O-CG 3.41Å; N353-L357 PolarHBondContact O-N 3.46Å; N353-A432 HydrophobicContact CB-CB 4.05Å; N353-Q434 WeakPolarHBondContact OD1-CB 3.47Å; N353-Q434 PolarHBondContact OD1-N 2.92Å; N353-Y435 PolarHBondContact OD1-N 3.44Å
354	E	88.7	Confident	81	Confident	96 Å²	96	51.9 Å²	51.9	45%	0.449	30%	0.303	S	S	.	.	H	α-helix	trans	-60.4	-42.6	175.9	-70.7	-56.2	132.5	0	0	112	T349 N350 L356 L357 A358	T349-E354 HydrophobicContact CG2-CG 3.47Å; T349-E354 VanDerWaalsContact CG2-CG 3.47Å; N350-E354 PolarHBondContact O-N 3.45Å; E354-L356 PolarHBondContact O-N 2.89Å; E354-L357 PolarHBondContact O-N 2.86Å; E354-A358 VanDerWaalsContact O-CB 3.25Å; E354-A358 WeakPolarHBondContact O-CB 3.16Å; E354-A358 PolarHBondContact O-N 3.46Å
355	L	89.9	Confident	82	Confident	75 Å²	75	54 Å²	54	39%	0.393	32%	0.315	S	S	.	.	H	α-helix	trans	-59.6	-45	177.2	179	63.4	0	0	0	111.9	P351 L352 N353 A358 L359 L369	P351-L355 WeakPolarHBondContact O-CB 3.46Å; P351-L355 PolarHBondContact O-N 3.08Å; P351-L355 VanDerWaalsContact O-N 3.09Å; L352-L355 HydrophobicContact CD1-CD2 4.44Å; L352-L355 PolarHBondContact O-N 3.04Å; N353-L355 VanDerWaalsContact C-N 3.33Å; N353-L355 PolarHBondContact O-N 3.1Å; L355-A358 PolarHBondContact O-N 3.06Å; L355-L359 HydrophobicContact CD1-CD1 3.87Å; L355-L359 HydrophobicContact CD1-CG 4.31Å; L355-L359 HydrophobicContact CG-CD1 4.01Å; L355-L359 VanDerWaalsContact O-CG 3.28Å; L355-L359 WeakPolarHBondContact O-CG 3.36Å; L355-L359 PolarHBondContact O-N 3.2Å; L355-L359 VanDerWaalsContact O-N 3.13Å; L355-L369 HydrophobicContact CD2-CD2 4.09Å; L355-L369 HydrophobicContact CG-CD2 4.17Å
356	L	88.1	Confident	82.9	Confident	1 Å²	1	53 Å²	53	1%	0.005	30%	0.304	C	S	.	.	H	α-helix	trans	-66.9	-43.4	179.6	-76.2	163.3	0	0	0	111.7	L352 N353 E354 A358 L359 Q360 L369 I370 A432 Y435	L352-L356 HydrophobicContact CD1-CD1 4.4Å; L352-L356 HydrophobicContact CG-CD1 4.08Å; L352-L356 WeakPolarHBondContact O-CG 3Å; L352-L356 PolarHBondContact O-N 3.45Å; N353-L356 PolarHBondContact O-N 3.13Å; E354-L356 PolarHBondContact O-N 2.89Å; L356-A358 VanDerWaalsContact C-N 3.33Å; L356-A358 PolarHBondContact O-N 3.22Å; L356-L359 PolarHBondContact O-N 3.23Å; L356-Q360 WeakPolarHBondContact O-CB 3.4Å; L356-Q360 PolarHBondContact O-N 2.77Å; L356-Q360 VanDerWaalsContact O-N 3.1Å; L356-L369 HydrophobicContact CD2-CB 4.31Å; L356-L369 HydrophobicContact CD2-CD2 3.65Å; L356-L369 HydrophobicContact CD2-CG 4.03Å; L356-L369 HydrophobicContact CG-CD2 4.23Å; L356-I370 HydrophobicContact CD1-CD1 3.95Å; L356-I370 HydrophobicContact CD2-CD1 3.75Å; L356-I370 HydrophobicContact CD2-CG1 4.03Å; L356-A432 HydrophobicContact CD1-CB 3.7Å; L356-Y435 HydrophobicContact CB-CD1 3.97Å; L356-Y435 HydrophobicContact CB-CD2 3.65Å; L356-Y435 HydrophobicContact CB-CE1 4.25Å; L356-Y435 HydrophobicContact CB-CE2 3.94Å; L356-Y435 HydrophobicContact CB-CG 3.66Å; L356-Y435 HydrophobicContact CD1-CD1 3.78Å; L356-Y435 HydrophobicContact CD1-CE1 4.1Å; L356-Y435 HydrophobicContact CD1-CG 4.23Å; L356-Y435 HydrophobicContact CD2-CE1 4.09Å; L356-Y435 HydrophobicContact CG-CD1 4.31Å; L356-Y435 HydrophobicContact CG-CE1 4.39Å; L356-Y435 HydrophobicContact CG-CG 4.48Å
357	L	87.4	Confident	83.7	Confident	27 Å²	27	51 Å²	51	14%	0.141	29%	0.291	C	S	.	.	H	α-helix	trans	-64.4	-35.6	175.9	-70.6	173.1	0	0	0	112.7	N353 E354 P361 Q434 Y435 G439	N353-L357 WeakPolarHBondContact ND2-CD1 3.36Å; N353-L357 WeakPolarHBondContact O-CG 3.41Å; N353-L357 PolarHBondContact O-N 3.46Å; E354-L357 PolarHBondContact O-N 2.86Å; L357-P361 WeakPolarHBondContact O-CD 3.43Å; L357-Q434 HydrophobicContact CD1-CG 4.22Å; L357-Y435 HydrophobicContact CD2-CD2 4.12Å; L357-G439 WeakPolarHBondContact CD2-O 3.01Å
358	A	87.4	Confident	84.3	Confident	73 Å²	73	50 Å²	50	60%	0.603	28%	0.284	S	S	*	.	H	α-helix	trans	-71.9	-30.6	178.3	0	0	0	0	0	113.2	E354 L355 L356 P361	E354-A358 VanDerWaalsContact O-CB 3.25Å; E354-A358 WeakPolarHBondContact O-CB 3.16Å; E354-A358 PolarHBondContact O-N 3.46Å; L355-A358 PolarHBondContact O-N 3.06Å; L356-A358 VanDerWaalsContact C-N 3.33Å; L356-A358 PolarHBondContact O-N 3.22Å; A358-P361 WeakPolarHBondContact O-CD 3.33Å
359	L	84.9	Confident	84.6	Confident	50 Å²	50	49 Å²	49	26%	0.262	28%	0.279	S	S	.	.	H	α-helix	trans	-84.6	-24.1	179.3	-70.3	170.9	0	0	0	113.1	L355 L356 P361 V362 L365 L369	L355-L359 HydrophobicContact CD1-CD1 3.87Å; L355-L359 HydrophobicContact CD1-CG 4.31Å; L355-L359 HydrophobicContact CG-CD1 4.01Å; L355-L359 VanDerWaalsContact O-CG 3.28Å; L355-L359 WeakPolarHBondContact O-CG 3.36Å; L355-L359 PolarHBondContact O-N 3.2Å; L355-L359 VanDerWaalsContact O-N 3.13Å; L356-L359 PolarHBondContact O-N 3.23Å; L359-P361 VanDerWaalsContact C-CD 3.44Å; L359-V362 PolarHBondContact O-N 3.01Å; L359-V362 VanDerWaalsContact O-N 3.09Å; L359-L365 HydrophobicContact CB-CB 4.33Å; L359-L365 HydrophobicContact CD2-CB 4.46Å; L359-L365 HydrophobicContact CD2-CD1 4.07Å; L359-L369 HydrophobicContact CD1-CD2 3.55Å
360	Q	81.9	Confident	84.8	Confident	15 Å²	15	44.1 Å²	44.1	7%	0.07	25%	0.249	C	C	.	.	T	Hydrogen-bonded Turn	trans	-56.9	-35.9	-176.8	-177	159	28.8	0	0	116	S71 L356 V362 D366 Y435 S440	S71-Q360 PolarHBondContact OG-NE2 3.08Å; L356-Q360 WeakPolarHBondContact O-CB 3.4Å; L356-Q360 PolarHBondContact O-N 2.77Å; L356-Q360 VanDerWaalsContact O-N 3.1Å; Q360-V362 PolarHBondContact O-N 2.76Å; Q360-D366 HydrophobicContact CB-CB 4.3Å; Q360-D366 WeakPolarHBondContact CG-OD2 3.24Å; Q360-Y435 HydrophobicContact CB-CE2 4.45Å; Q360-S440 VanDerWaalsContact OE1-CB 3.27Å
361	P	78.1	Confident	84.5	Confident	103 Å²	103	45.8 Å²	45.8	67%	0.669	26%	0.259	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.5	-21.7	176.1	-24.5	35.1	0	0	0	114.2	L357 A358 L359	L357-P361 WeakPolarHBondContact O-CD 3.43Å; A358-P361 WeakPolarHBondContact O-CD 3.33Å; L359-P361 VanDerWaalsContact C-CD 3.44Å
362	V	79.9	Confident	84.4	Confident	88 Å²	88	47.4 Å²	47.4	53%	0.533	27%	0.269	S	S	.	.	S	Bend	trans	-104	80.8	-179.7	-173.5	0	0	0	0	109	L359 Q360 L365	L359-V362 PolarHBondContact O-N 3.01Å; L359-V362 VanDerWaalsContact O-N 3.09Å; Q360-V362 PolarHBondContact O-N 2.76Å; V362-L365 HydrophobicContact CB-CD1 3.89Å; V362-L365 HydrophobicContact CB-CG 4.37Å; V362-L365 HydrophobicContact CG1-CD1 3.69Å; V362-L365 HydrophobicContact CG1-CG 4.09Å; V362-L365 WeakPolarHBondContact O-CB 3.35Å; V362-L365 WeakPolarHBondContact O-CG 3.26Å; V362-L365 PolarHBondContact O-N 3.04Å
363	F	68.9	Low	84.4	Confident	76 Å²	76	47.5 Å²	47.5	33%	0.333	27%	0.269	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.9	133.8	176.3	-177.6	-99.4	0	0	0	111	I12 I16 F68	I12-F363 HydrophobicContact CG2-CE1 4.42Å; I16-F363 HydrophobicContact CD1-CE1 3.47Å; I16-F363 VanDerWaalsContact CD1-CE1 3.47Å; I16-F363 HydrophobicContact CD1-CZ 3.79Å; F68-F363 HydrophobicContact CD1-CE2 4.49Å; F68-F363 AromaticContact CD2-CD2 3.57Å; F68-F363 HydrophobicContact CD2-CD2 3.57Å; F68-F363 AromaticContact CD2-CE2 3.68Å; F68-F363 HydrophobicContact CD2-CE2 3.68Å; F68-F363 HydrophobicContact CE1-CE2 4.43Å; F68-F363 AromaticContact CE2-CD2 3.35Å; F68-F363 HydrophobicContact CE2-CD2 3.35Å; F68-F363 AromaticContact CE2-CE2 3.61Å; F68-F363 HydrophobicContact CE2-CE2 3.61Å; F68-F363 HydrophobicContact CE2-CG 4.05Å; F68-F363 HydrophobicContact CE2-CZ 4.47Å; F68-F363 HydrophobicContact CG-CD2 4.45Å; F68-F363 HydrophobicContact CG-CE2 4.13Å; F68-F363 HydrophobicContact CZ-CD2 4.1Å; F68-F363 HydrophobicContact CZ-CE2 4.01Å; F68-F363 HydrophobicContact CZ-CZ 4.48Å
364	P	77	Confident	84.4	Confident	38 Å²	38	47.8 Å²	47.8	25%	0.247	27%	0.271	C	S	.	.	T	Hydrogen-bonded Turn	cis	-108.1	38.4	7.3	41	-34.8	0	0	0	114.6	I16 D366 Y367 I368	I16-P364 HydrophobicContact CD1-CB 4.25Å; I16-P364 HydrophobicContact CD1-CG 4.26Å; P364-D366 PolarHBondContact O-N 3.24Å; P364-Y367 WeakPolarHBondContact O-CB 3.22Å; P364-Y367 PolarHBondContact O-N 3.3Å; P364-I368 HydrophobicContact CG-CD1 4.18Å; P364-I368 WeakPolarHBondContact O-CG1 3.39Å; P364-I368 PolarHBondContact O-N 2.97Å; P364-I368 VanDerWaalsContact O-N 3.11Å
365	L	81.7	Confident	84.4	Confident	75 Å²	75	45.9 Å²	45.9	39%	0.393	27%	0.266	S	S	.	.	H	α-helix	trans	-65.7	-40.4	-171.6	-68.6	-176.8	0	0	0	114	L359 V362 I368 L369	L359-L365 HydrophobicContact CB-CB 4.33Å; L359-L365 HydrophobicContact CD2-CB 4.46Å; L359-L365 HydrophobicContact CD2-CD1 4.07Å; V362-L365 HydrophobicContact CB-CD1 3.89Å; V362-L365 HydrophobicContact CB-CG 4.37Å; V362-L365 HydrophobicContact CG1-CD1 3.69Å; V362-L365 HydrophobicContact CG1-CG 4.09Å; V362-L365 WeakPolarHBondContact O-CB 3.35Å; V362-L365 WeakPolarHBondContact O-CG 3.26Å; V362-L365 PolarHBondContact O-N 3.04Å; L365-I368 PolarHBondContact O-N 3.42Å; L365-L369 WeakPolarHBondContact O-CB 3.39Å; L365-L369 PolarHBondContact O-N 2.91Å
366	D	82.5	Confident	84.6	Confident	3 Å²	3	42.9 Å²	42.9	2%	0.016	25%	0.249	C	C	.	.	H	α-helix	trans	-63.2	-40.9	176.7	64	-25.3	0	0	0	112.1	Q360 P364 L369 I370 Y435	Q360-D366 HydrophobicContact CB-CB 4.3Å; Q360-D366 WeakPolarHBondContact CG-OD2 3.24Å; P364-D366 PolarHBondContact O-N 3.24Å; D366-L369 PolarHBondContact O-N 3.44Å; D366-I370 PolarHBondContact O-N 3.31Å; D366-Y435 HydrophobicContact CB-CE2 4.31Å; D366-Y435 WeakPolarHBondContact CB-OH 3.1Å; D366-Y435 PolarHBondContact OD2-OH 3.18Å
367	Y	82.8	Confident	84.9	Confident	13 Å²	13	42.9 Å²	42.9	5%	0.051	25%	0.249	C	C	.	.	H	α-helix	trans	-58.5	-49.1	172.9	-174.5	-74.5	0	0	0	111.7	V20 P64 V65 P364 L369 T371	V20-Y367 HydrophobicContact CB-CE1 4.37Å; V20-Y367 HydrophobicContact CG1-CE1 4.23Å; V20-Y367 WeakPolarHBondContact CG1-OH 3.46Å; V20-Y367 HydrophobicContact CG2-CD1 4.49Å; V20-Y367 HydrophobicContact CG2-CE1 3.45Å; V20-Y367 VanDerWaalsContact CG2-CE1 3.45Å; P64-Y367 HydrophobicContact CB-CD2 3.56Å; P64-Y367 HydrophobicContact CB-CE2 3.99Å; P64-Y367 HydrophobicContact CB-CG 4.14Å; P64-Y367 HydrophobicContact CG-CD2 3.63Å; P64-Y367 HydrophobicContact CG-CE2 3.53Å; P64-Y367 HydrophobicContact CG-CG 4.27Å; V65-Y367 HydrophobicContact CG2-CE2 3.83Å; P364-Y367 WeakPolarHBondContact O-CB 3.22Å; P364-Y367 PolarHBondContact O-N 3.3Å; Y367-L369 VanDerWaalsContact C-N 3.3Å; Y367-L369 PolarHBondContact O-N 2.85Å; Y367-T371 WeakPolarHBondContact O-CB 3.5Å; Y367-T371 PolarHBondContact O-N 2.88Å; Y367-T371 PolarHBondContact O-OG1 3.25Å
368	I	84.3	Confident	85.1	Confident	87 Å²	87	41.6 Å²	41.6	45%	0.446	24%	0.243	S	C	.	.	H	α-helix	trans	-61.8	-43	178.1	-66.8	167.5	0	0	0	109.5	P364 L365 T371 V372	P364-I368 HydrophobicContact CG-CD1 4.18Å; P364-I368 WeakPolarHBondContact O-CG1 3.39Å; P364-I368 PolarHBondContact O-N 2.97Å; P364-I368 VanDerWaalsContact O-N 3.11Å; L365-I368 PolarHBondContact O-N 3.42Å; I368-T371 WeakPolarHBondContact O-CB 3.4Å; I368-T371 PolarHBondContact O-N 3.39Å; I368-V372 HydrophobicContact CG2-CG2 4.25Å; I368-V372 WeakPolarHBondContact O-CB 3.32Å; I368-V372 VanDerWaalsContact O-CG2 3.28Å; I368-V372 WeakPolarHBondContact O-CG2 3.47Å; I368-V372 PolarHBondContact O-N 3.43Å
369	L	87.9	Confident	85.3	Confident	40 Å²	40	40.7 Å²	40.7	21%	0.209	23%	0.227	C	C	.	.	H	α-helix	trans	-64.1	-47.6	-179	-174.7	58.7	0	0	0	112.1	L355 L356 L359 L365 D366 Y367 T371 V372 I373	L355-L369 HydrophobicContact CD2-CD2 4.09Å; L355-L369 HydrophobicContact CG-CD2 4.17Å; L356-L369 HydrophobicContact CD2-CB 4.31Å; L356-L369 HydrophobicContact CD2-CD2 3.65Å; L356-L369 HydrophobicContact CD2-CG 4.03Å; L356-L369 HydrophobicContact CG-CD2 4.23Å; L359-L369 HydrophobicContact CD1-CD2 3.55Å; L365-L369 WeakPolarHBondContact O-CB 3.39Å; L365-L369 PolarHBondContact O-N 2.91Å; D366-L369 PolarHBondContact O-N 3.44Å; Y367-L369 VanDerWaalsContact C-N 3.3Å; Y367-L369 PolarHBondContact O-N 2.85Å; L369-T371 VanDerWaalsContact C-N 3.27Å; L369-T371 PolarHBondContact O-N 2.84Å; L369-V372 PolarHBondContact O-N 2.89Å; L369-V372 VanDerWaalsContact O-N 3.16Å; L369-I373 HydrophobicContact CD1-CD1 4.45Å; L369-I373 HydrophobicContact CD1-CG1 4.49Å; L369-I373 HydrophobicContact CG-CD1 4.07Å; L369-I373 VanDerWaalsContact O-CG1 3.23Å; L369-I373 WeakPolarHBondContact O-CG1 3.33Å; L369-I373 PolarHBondContact O-N 3.5Å
370	I	87.3	Confident	85.8	Confident	2 Å²	2	38.3 Å²	38.3	1%	0.01	22%	0.215	C	C	.	.	H	α-helix	trans	-59.8	-38.9	174.8	-70.3	-57.3	0	0	0	111.6	P64 L356 D366 I373 T374 I428 Y435	P64-I370 HydrophobicContact CB-CB 4.35Å; P64-I370 HydrophobicContact CB-CG2 4.26Å; P64-I370 HydrophobicContact CG-CG2 4.18Å; L356-I370 HydrophobicContact CD1-CD1 3.95Å; L356-I370 HydrophobicContact CD2-CD1 3.75Å; L356-I370 HydrophobicContact CD2-CG1 4.03Å; D366-I370 PolarHBondContact O-N 3.31Å; I370-I373 HydrophobicContact CD1-CD1 4.19Å; I370-I373 PolarHBondContact O-N 3.49Å; I370-T374 WeakPolarHBondContact O-CB 3.34Å; I370-T374 PolarHBondContact O-N 3.28Å; I370-T374 PolarHBondContact O-OG1 2.82Å; I370-I428 HydrophobicContact CD1-CG2 3.97Å; I370-I428 HydrophobicContact CG2-CD1 4.4Å; I370-Y435 HydrophobicContact CD1-CE1 3.87Å; I370-Y435 HydrophobicContact CG1-CE1 3.9Å
371	T	85	Confident	86.4	Confident	41 Å²	41	37.6 Å²	37.6	25%	0.252	21%	0.212	S	C	.	.	H	α-helix	trans	-63.4	-45.1	175.4	-57.4	0	0	0	0	111.1	Y367 I368 L369 I373 T374 V375	Y367-T371 WeakPolarHBondContact O-CB 3.5Å; Y367-T371 PolarHBondContact O-N 2.88Å; Y367-T371 PolarHBondContact O-OG1 3.25Å; I368-T371 WeakPolarHBondContact O-CB 3.4Å; I368-T371 PolarHBondContact O-N 3.39Å; L369-T371 VanDerWaalsContact C-N 3.27Å; L369-T371 PolarHBondContact O-N 2.84Å; T371-I373 PolarHBondContact O-N 2.84Å; T371-T374 PolarHBondContact O-N 2.92Å; T371-V375 HydrophobicContact CG2-CG2 4.49Å; T371-V375 WeakPolarHBondContact O-CB 3.49Å; T371-V375 VanDerWaalsContact O-CG2 3.32Å; T371-V375 WeakPolarHBondContact O-CG2 3.32Å; T371-V375 PolarHBondContact O-N 3.41Å
372	V	88.2	Confident	87	Confident	85 Å²	85	34.1 Å²	34.1	52%	0.515	19%	0.186	S	C	.	.	H	α-helix	trans	-62.3	-41.7	176.6	168.8	0	0	0	0	111.4	I368 L369 V375 Y376	I368-V372 HydrophobicContact CG2-CG2 4.25Å; I368-V372 WeakPolarHBondContact O-CB 3.32Å; I368-V372 VanDerWaalsContact O-CG2 3.28Å; I368-V372 WeakPolarHBondContact O-CG2 3.47Å; I368-V372 PolarHBondContact O-N 3.43Å; L369-V372 PolarHBondContact O-N 2.89Å; L369-V372 VanDerWaalsContact O-N 3.16Å; V372-V375 PolarHBondContact O-N 3.33Å; V372-Y376 VanDerWaalsContact O-CB 3.32Å; V372-Y376 WeakPolarHBondContact O-CB 3.5Å; V372-Y376 PolarHBondContact O-N 3.4Å
373	I	91.2	Very high	87.5	Confident	6 Å²	6	30.4 Å²	30.4	3%	0.031	17%	0.165	C	C	.	.	H	α-helix	trans	-60.7	-47.4	175.3	-67.2	167.1	0	0	0	110.3	F319 L352 L369 I370 T371 V375 Y376 F377	F319-I373 HydrophobicContact CE1-CD1 4.35Å; F319-I373 HydrophobicContact CE1-CG1 4.1Å; F319-I373 HydrophobicContact CE1-CG2 4.2Å; F319-I373 HydrophobicContact CZ-CB 4.32Å; F319-I373 HydrophobicContact CZ-CG1 3.84Å; F319-I373 HydrophobicContact CZ-CG2 3.91Å; L352-I373 HydrophobicContact CD1-CD1 4.18Å; L369-I373 HydrophobicContact CD1-CD1 4.45Å; L369-I373 HydrophobicContact CD1-CG1 4.49Å; L369-I373 HydrophobicContact CG-CD1 4.07Å; L369-I373 VanDerWaalsContact O-CG1 3.23Å; L369-I373 WeakPolarHBondContact O-CG1 3.33Å; L369-I373 PolarHBondContact O-N 3.5Å; I370-I373 HydrophobicContact CD1-CD1 4.19Å; I370-I373 PolarHBondContact O-N 3.49Å; T371-I373 PolarHBondContact O-N 2.84Å; I373-V375 PolarHBondContact O-N 3.21Å; I373-Y376 WeakPolarHBondContact O-CB 3.44Å; I373-Y376 PolarHBondContact O-N 3.33Å; I373-F377 HydrophobicContact CG2-CD2 3.8Å; I373-F377 HydrophobicContact CG2-CE2 3.51Å; I373-F377 VanDerWaalsContact O-CD2 3.23Å; I373-F377 WeakPolarHBondContact O-CD2 3.46Å; I373-F377 PolarHBondContact O-N 3.49Å
374	T	89.8	Confident	88.6	Confident	10 Å²	10	26.8 Å²	26.8	6%	0.061	15%	0.149	C	C	.	.	H	α-helix	trans	-60.9	-47.8	178.4	-56.2	0	0	0	0	111.2	S60 I370 T371 Y376 F377 V378	S60-T374 WeakPolarHBondContact OG-CG2 3.47Å; I370-T374 WeakPolarHBondContact O-CB 3.34Å; I370-T374 PolarHBondContact O-N 3.28Å; I370-T374 PolarHBondContact O-OG1 2.82Å; T371-T374 PolarHBondContact O-N 2.92Å; T374-Y376 VanDerWaalsContact C-N 3.31Å; T374-Y376 PolarHBondContact O-N 3.48Å; T374-F377 PolarHBondContact O-N 3.49Å; T374-V378 WeakPolarHBondContact O-CG2 3.23Å; T374-V378 PolarHBondContact O-N 3.33Å
375	V	89	Confident	89.3	Confident	56 Å²	56	25 Å²	25	34%	0.339	14%	0.138	S	C	.	.	H	α-helix	trans	-62.1	-40.1	177.2	170.5	0	0	0	0	110.9	T371 V372 I373 F377 V378 L379	T371-V375 HydrophobicContact CG2-CG2 4.49Å; T371-V375 WeakPolarHBondContact O-CB 3.49Å; T371-V375 VanDerWaalsContact O-CG2 3.32Å; T371-V375 WeakPolarHBondContact O-CG2 3.32Å; T371-V375 PolarHBondContact O-N 3.41Å; V372-V375 PolarHBondContact O-N 3.33Å; I373-V375 PolarHBondContact O-N 3.21Å; V375-F377 PolarHBondContact O-N 2.82Å; V375-V378 PolarHBondContact O-N 3.36Å; V375-L379 HydrophobicContact CG1-CD1 3.77Å; V375-L379 HydrophobicContact CG1-CG 4.05Å; V375-L379 WeakPolarHBondContact O-CB 3.43Å; V375-L379 VanDerWaalsContact O-CG 3.25Å; V375-L379 WeakPolarHBondContact O-CG 3.19Å; V375-L379 PolarHBondContact O-N 3.47Å
376	Y	92.8	Very high	89.6	Confident	12 Å²	12	27.2 Å²	27.2	5%	0.047	14%	0.141	C	C	.	.	H	α-helix	trans	-59.2	-46.6	175.1	172	-91.6	0	0	0	111.9	M216 F312 V315 A316 F319 V372 I373 T374 V378 L379 T380	M216-Y376 HydrophobicContact CG-CE1 4.02Å; M216-Y376 HydrophobicContact SD-CE1 3.98Å; F312-Y376 HydrophobicContact CB-CE2 4.4Å; F312-Y376 AromaticContact CD1-CD2 3.73Å; F312-Y376 HydrophobicContact CD1-CD2 3.73Å; F312-Y376 AromaticContact CD1-CE2 3.54Å; F312-Y376 HydrophobicContact CD1-CE2 3.54Å; F312-Y376 AromaticContact CE1-CD2 3.89Å; F312-Y376 HydrophobicContact CE1-CD2 3.89Å; F312-Y376 HydrophobicContact CE1-CE2 4.17Å; F312-Y376 HydrophobicContact CG-CE2 4.27Å; F312-Y376 PolarHBondContact O-OH 3.47Å; V315-Y376 HydrophobicContact CG1-CD2 4.34Å; V315-Y376 HydrophobicContact CG1-CE1 4.32Å; V315-Y376 HydrophobicContact CG1-CE2 4.11Å; A316-Y376 WeakPolarHBondContact CB-OH 3.2Å; F319-Y376 HydrophobicContact CD2-CD1 4.12Å; F319-Y376 AromaticContact CD2-CE1 3.77Å; F319-Y376 HydrophobicContact CD2-CE1 3.77Å; F319-Y376 AromaticContact CE2-CD1 3.47Å; F319-Y376 HydrophobicContact CE2-CD1 3.47Å; F319-Y376 VanDerWaalsContact CE2-CD1 3.47Å; F319-Y376 AromaticContact CE2-CE1 3.55Å; F319-Y376 HydrophobicContact CE2-CE1 3.55Å; F319-Y376 HydrophobicContact CE2-CG 4.28Å; V372-Y376 VanDerWaalsContact O-CB 3.32Å; V372-Y376 WeakPolarHBondContact O-CB 3.5Å; V372-Y376 PolarHBondContact O-N 3.4Å; I373-Y376 WeakPolarHBondContact O-CB 3.44Å; I373-Y376 PolarHBondContact O-N 3.33Å; T374-Y376 VanDerWaalsContact C-N 3.31Å; T374-Y376 PolarHBondContact O-N 3.48Å; Y376-V378 VanDerWaalsContact C-N 3.33Å; Y376-V378 PolarHBondContact O-N 3.01Å; Y376-L379 PolarHBondContact O-N 3.19Å; Y376-T380 HydrophobicContact CD1-CG2 4.31Å; Y376-T380 HydrophobicContact CD2-CG2 4.13Å; Y376-T380 HydrophobicContact CE1-CG2 3.92Å; Y376-T380 HydrophobicContact CE2-CG2 3.72Å; Y376-T380 HydrophobicContact CG-CG2 4.43Å; Y376-T380 WeakPolarHBondContact O-CB 3.46Å; Y376-T380 WeakPolarHBondContact O-CG2 3.49Å; Y376-T380 PolarHBondContact O-N 3.13Å; Y376-T380 PolarHBondContact O-OG1 3.36Å
377	F	93.9	Very high	89.8	Confident	0 Å²	0	28.3 Å²	28.3	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-62.3	-40.1	176.2	-77.7	-59.5	0	0	0	112.2	T212 M216 F319 I373 T374 V375 T380 S381 T424 M427 L431 F500	T212-F377 HydrophobicContact CG2-CD1 3.62Å; T212-F377 HydrophobicContact CG2-CE1 4.39Å; M216-F377 HydrophobicContact SD-CD1 4.38Å; M216-F377 HydrophobicContact SD-CE1 3.84Å; F319-F377 HydrophobicContact CD2-CE1 4.36Å; F319-F377 HydrophobicContact CD2-CE2 4.48Å; F319-F377 AromaticContact CD2-CZ 3.87Å; F319-F377 HydrophobicContact CD2-CZ 3.87Å; F319-F377 HydrophobicContact CE2-CE2 4.37Å; F319-F377 HydrophobicContact CE2-CZ 4.18Å; F319-F377 HydrophobicContact CG-CZ 4.22Å; I373-F377 HydrophobicContact CG2-CD2 3.8Å; I373-F377 HydrophobicContact CG2-CE2 3.51Å; I373-F377 VanDerWaalsContact O-CD2 3.23Å; I373-F377 WeakPolarHBondContact O-CD2 3.46Å; I373-F377 PolarHBondContact O-N 3.49Å; T374-F377 PolarHBondContact O-N 3.49Å; V375-F377 PolarHBondContact O-N 2.82Å; F377-T380 WeakPolarHBondContact CA-OG1 3.24Å; F377-T380 PolarHBondContact O-OG1 3.09Å; F377-S381 VanDerWaalsContact O-CB 3.25Å; F377-S381 WeakPolarHBondContact O-CB 3.16Å; F377-S381 PolarHBondContact O-N 3.29Å; F377-S381 PolarHBondContact O-OG 3.04Å; F377-T424 HydrophobicContact CB-CG2 3.92Å; F377-T424 HydrophobicContact CD2-CG2 3.62Å; F377-T424 HydrophobicContact CE2-CG2 4.46Å; F377-T424 HydrophobicContact CG-CG2 3.99Å; F377-M427 HydrophobicContact CD1-CE 3.5Å; F377-M427 VanDerWaalsContact CD1-CE 3.5Å; F377-M427 HydrophobicContact CD2-CE 3.81Å; F377-M427 HydrophobicContact CE1-CE 3.26Å; F377-M427 HydrophobicContact CE1-SD 4.2Å; F377-M427 HydrophobicContact CE2-CE 3.59Å; F377-M427 HydrophobicContact CG-CE 3.77Å; F377-M427 HydrophobicContact CZ-CE 3.32Å; F377-M427 HydrophobicContact CZ-SD 4.21Å; F377-L431 HydrophobicContact CE2-CD1 3.82Å; F377-L431 HydrophobicContact CZ-CD1 3.91Å; F377-F500 HydrophobicContact CE1-CZ 4.45Å
378	V	92.2	Very high	89.9	Confident	1 Å²	1	30.8 Å²	30.8	1%	0.006	16%	0.159	C	C	.	.	H	α-helix	trans	-64.1	-48.1	175.4	172.6	0	0	0	0	111.4	F27 L57 T374 V375 Y376 T380 S381 M382 V421	F27-V378 HydrophobicContact CE1-CG1 4.34Å; F27-V378 HydrophobicContact CZ-CG1 4.22Å; L57-V378 HydrophobicContact CD2-CG2 4.1Å; T374-V378 WeakPolarHBondContact O-CG2 3.23Å; T374-V378 PolarHBondContact O-N 3.33Å; V375-V378 PolarHBondContact O-N 3.36Å; Y376-V378 VanDerWaalsContact C-N 3.33Å; Y376-V378 PolarHBondContact O-N 3.01Å; V378-T380 PolarHBondContact O-N 3.26Å; V378-S381 WeakPolarHBondContact O-CB 3.42Å; V378-S381 PolarHBondContact O-N 3.33Å; V378-M382 HydrophobicContact CG1-CG 4.49Å; V378-M382 HydrophobicContact CG1-SD 3.84Å; V378-M382 WeakPolarHBondContact O-CG 3.49Å; V378-M382 PolarHBondContact O-N 3Å; V378-V421 HydrophobicContact CG2-CG2 3.54Å
379	L	92.2	Very high	90	Very high	54 Å²	54	26.7 Å²	26.7	28%	0.283	14%	0.139	S	C	.	.	H	α-helix	trans	-64.1	-41.4	-179	-71	177.6	0	0	0	112.6	F27 V375 Y376 M382 A383	F27-L379 HydrophobicContact CE2-CD2 4.27Å; F27-L379 HydrophobicContact CZ-CD2 4.47Å; V375-L379 HydrophobicContact CG1-CD1 3.77Å; V375-L379 HydrophobicContact CG1-CG 4.05Å; V375-L379 WeakPolarHBondContact O-CB 3.43Å; V375-L379 VanDerWaalsContact O-CG 3.25Å; V375-L379 WeakPolarHBondContact O-CG 3.19Å; V375-L379 PolarHBondContact O-N 3.47Å; Y376-L379 PolarHBondContact O-N 3.19Å; L379-M382 HydrophobicContact CD2-CE 3.91Å; L379-M382 HydrophobicContact CD2-SD 4.33Å; L379-M382 WeakPolarHBondContact O-CB 3.47Å; L379-M382 PolarHBondContact O-N 3.26Å; L379-A383 PolarHBondContact O-N 3.43Å
380	T	94.6	Very high	89.9	Confident	0 Å²	0	24.9 Å²	24.9	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-67.4	-43.1	176.5	50.9	0	0	0	0	110.9	G215 M216 M219 Y376 F377 V378 M382 A383 G384	G215-T380 WeakPolarHBondContact CA-O 3.43Å; M216-T380 HydrophobicContact CB-CG2 4.48Å; M216-T380 HydrophobicContact CG-CG2 3.99Å; M219-T380 HydrophobicContact SD-CG2 3.96Å; Y376-T380 HydrophobicContact CD1-CG2 4.31Å; Y376-T380 HydrophobicContact CD2-CG2 4.13Å; Y376-T380 HydrophobicContact CE1-CG2 3.92Å; Y376-T380 HydrophobicContact CE2-CG2 3.72Å; Y376-T380 HydrophobicContact CG-CG2 4.43Å; Y376-T380 WeakPolarHBondContact O-CB 3.46Å; Y376-T380 WeakPolarHBondContact O-CG2 3.49Å; Y376-T380 PolarHBondContact O-N 3.13Å; Y376-T380 PolarHBondContact O-OG1 3.36Å; F377-T380 WeakPolarHBondContact CA-OG1 3.24Å; F377-T380 PolarHBondContact O-OG1 3.09Å; V378-T380 PolarHBondContact O-N 3.26Å; T380-M382 VanDerWaalsContact C-N 3.33Å; T380-M382 PolarHBondContact O-N 3.04Å; T380-A383 WeakPolarHBondContact O-CB 3.39Å; T380-A383 PolarHBondContact O-N 3.1Å; T380-A383 VanDerWaalsContact O-N 3.08Å; T380-G384 PolarHBondContact O-N 3Å
381	S	94.9	Very high	89.7	Confident	0 Å²	0	29.9 Å²	29.9	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-56.1	-46.5	172.8	-58.2	0	0	0	0	112.2	T212 F377 V378 A383 G384 I385 I420	T212-S381 WeakPolarHBondContact CB-OG 3.47Å; T212-S381 WeakPolarHBondContact CG2-OG 3.17Å; T212-S381 PolarHBondContact OG1-OG 3.42Å; F377-S381 VanDerWaalsContact O-CB 3.25Å; F377-S381 WeakPolarHBondContact O-CB 3.16Å; F377-S381 PolarHBondContact O-N 3.29Å; F377-S381 PolarHBondContact O-OG 3.04Å; V378-S381 WeakPolarHBondContact O-CB 3.42Å; V378-S381 PolarHBondContact O-N 3.33Å; S381-A383 VanDerWaalsContact C-N 3.32Å; S381-A383 PolarHBondContact O-N 2.91Å; S381-G384 WeakPolarHBondContact O-CA 3.43Å; S381-G384 PolarHBondContact O-N 3.15Å; S381-G384 VanDerWaalsContact O-N 3.12Å; S381-I385 WeakPolarHBondContact O-CG1 3.48Å; S381-I385 PolarHBondContact O-N 3.5Å; S381-I420 WeakPolarHBondContact OG-CG2 3.22Å
382	M	90.8	Very high	89.4	Confident	29 Å²	29	34 Å²	34	14%	0.143	16%	0.163	C	C	.	.	H	α-helix	trans	-59.6	-42.1	175.3	-71.5	166.7	31.6	0	0	112.1	F27 Y31 V378 L379 T380 G384 R386 L417	F27-M382 HydrophobicContact CZ-SD 4.31Å; Y31-M382 HydrophobicContact CD2-CE 3.52Å; Y31-M382 HydrophobicContact CD2-SD 3.85Å; Y31-M382 HydrophobicContact CE2-CE 3.15Å; Y31-M382 HydrophobicContact CE2-CG 4Å; Y31-M382 HydrophobicContact CE2-SD 3.37Å; Y31-M382 WeakPolarHBondContact CE2-SD 3.34Å; V378-M382 HydrophobicContact CG1-CG 4.49Å; V378-M382 HydrophobicContact CG1-SD 3.84Å; V378-M382 WeakPolarHBondContact O-CG 3.49Å; V378-M382 PolarHBondContact O-N 3Å; L379-M382 HydrophobicContact CD2-CE 3.91Å; L379-M382 HydrophobicContact CD2-SD 4.33Å; L379-M382 WeakPolarHBondContact O-CB 3.47Å; L379-M382 PolarHBondContact O-N 3.26Å; T380-M382 VanDerWaalsContact C-N 3.33Å; T380-M382 PolarHBondContact O-N 3.04Å; M382-G384 VanDerWaalsContact C-N 3.31Å; M382-G384 PolarHBondContact O-N 3.08Å; M382-R386 VanDerWaalsContact O-CB 3.29Å; M382-R386 WeakPolarHBondContact O-CB 3.38Å; M382-R386 PolarHBondContact O-N 2.93Å; M382-L417 HydrophobicContact CG-CD1 4.21Å; M382-L417 HydrophobicContact CG-CD2 3.84Å
383	A	90.9	Very high	88.8	Confident	10 Å²	10	38.1 Å²	38.1	8%	0.083	17%	0.174	C	C	.	.	H	α-helix	trans	-64.3	-37.1	175.9	0	0	0	0	0	112	M219 L379 T380 S381 N387	M219-A383 HydrophobicContact CB-CB 3.76Å; M219-A383 HydrophobicContact CG-CB 4.13Å; M219-A383 HydrophobicContact SD-CB 4.16Å; L379-A383 PolarHBondContact O-N 3.43Å; T380-A383 WeakPolarHBondContact O-CB 3.39Å; T380-A383 PolarHBondContact O-N 3.1Å; T380-A383 VanDerWaalsContact O-N 3.08Å; S381-A383 VanDerWaalsContact C-N 3.32Å; S381-A383 PolarHBondContact O-N 2.91Å; A383-N387 WeakPolarHBondContact O-CB 3.48Å; A383-N387 PolarHBondContact O-N 3.42Å; A383-N387 VanDerWaalsContact O-N 3.14Å; A383-N387 PolarHBondContact O-ND2 3.43Å
384	G	92.2	Very high	88.3	Confident	0 Å²	0	48.9 Å²	48.9	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-62.8	-55	173.3	0	0	0	0	0	112.3	Y211 T380 S381 M382 R386 N387 M388	Y211-G384 WeakPolarHBondContact O-CA 3.39Å; T380-G384 PolarHBondContact O-N 3Å; S381-G384 WeakPolarHBondContact O-CA 3.43Å; S381-G384 PolarHBondContact O-N 3.15Å; S381-G384 VanDerWaalsContact O-N 3.12Å; M382-G384 VanDerWaalsContact C-N 3.31Å; M382-G384 PolarHBondContact O-N 3.08Å; G384-R386 VanDerWaalsContact C-N 3.29Å; G384-R386 PolarHBondContact O-N 3.15Å; G384-N387 PolarHBondContact O-N 3.39Å; G384-N387 VanDerWaalsContact O-N 3.16Å; G384-M388 WeakPolarHBondContact O-CB 3.22Å; G384-M388 PolarHBondContact O-N 3.27Å
385	I	91.8	Very high	87.9	Confident	1 Å²	1	54.5 Å²	54.5	1%	0.005	24%	0.243	C	C	.	.	H	α-helix	trans	-60.2	-39.9	179.7	-57	165.1	0	0	0	110.8	Y211 S381 N387 G389 I390 I400 L413 I416 L417 I420	Y211-I385 HydrophobicContact CD1-CB 4.18Å; Y211-I385 HydrophobicContact CD1-CG1 3.57Å; Y211-I385 HydrophobicContact CD2-CG1 3.94Å; Y211-I385 HydrophobicContact CE1-CB 4.45Å; Y211-I385 HydrophobicContact CE1-CG1 4.06Å; Y211-I385 HydrophobicContact CE2-CG1 4.4Å; Y211-I385 HydrophobicContact CG-CD1 4.46Å; Y211-I385 HydrophobicContact CG-CG1 3.49Å; Y211-I385 VanDerWaalsContact CG-CG1 3.49Å; S381-I385 WeakPolarHBondContact O-CG1 3.48Å; S381-I385 PolarHBondContact O-N 3.5Å; I385-N387 PolarHBondContact O-N 3.1Å; I385-G389 WeakPolarHBondContact O-CA 3.46Å; I385-G389 PolarHBondContact O-N 2.88Å; I385-I390 HydrophobicContact CG2-CG1 3.84Å; I385-I400 HydrophobicContact CB-CD1 4.45Å; I385-I400 HydrophobicContact CG2-CD1 3.35Å; I385-I400 HydrophobicContact CG2-CG1 4.24Å; I385-L413 HydrophobicContact CD1-CD1 3.77Å; I385-L413 HydrophobicContact CG2-CD1 4.17Å; I385-I416 HydrophobicContact CD1-CG2 3.83Å; I385-L417 HydrophobicContact CD1-CD2 4.08Å; I385-L417 HydrophobicContact CD1-CG 4.45Å; I385-I420 HydrophobicContact CD1-CD1 4.42Å
386	R	87.9	Confident	87.5	Confident	122 Å²	122	58 Å²	58	46%	0.46	25%	0.25	S	C	.	.	H	α-helix	trans	-63.7	-41.6	177.6	-176.2	-175.9	63.9	153.4	-1.3	112.5	M382 G384	M382-R386 VanDerWaalsContact O-CB 3.29Å; M382-R386 WeakPolarHBondContact O-CB 3.38Å; M382-R386 PolarHBondContact O-N 2.93Å; G384-R386 VanDerWaalsContact C-N 3.29Å; G384-R386 PolarHBondContact O-N 3.15Å
387	N	85.6	Confident	87.1	Confident	26 Å²	26	61.3 Å²	61.3	14%	0.139	27%	0.268	C	S	.	.	H	α-helix	trans	-79.6	-34.5	-176.2	-76.3	-39.4	0	0	0	112.9	Y214 V218 N222 A383 G384 I385 K517	Y214-N387 HydrophobicContact CE1-CB 3.93Å; V218-N387 VanDerWaalsContact CG1-ND2 3.27Å; V218-N387 WeakPolarHBondContact CG1-ND2 3.36Å; N222-N387 PolarHBondContact ND2-ND2 2.97Å; A383-N387 WeakPolarHBondContact O-CB 3.48Å; A383-N387 PolarHBondContact O-N 3.42Å; A383-N387 VanDerWaalsContact O-N 3.14Å; A383-N387 PolarHBondContact O-ND2 3.43Å; G384-N387 PolarHBondContact O-N 3.39Å; G384-N387 VanDerWaalsContact O-N 3.16Å; I385-N387 PolarHBondContact O-N 3.1Å; N387-K517 PolarHBondContact OD1-NZ 3.37Å
388	M	85.9	Confident	86.6	Confident	64 Å²	64	63.1 Å²	63.1	32%	0.315	28%	0.275	S	S	.	.	H	α-helix	trans	-90	-32.7	-178.6	-162.6	168.6	112.7	0	0	112.3	Y211 Y214 G384 W391	Y211-M388 HydrophobicContact CD1-CE 4.32Å; Y211-M388 HydrophobicContact CE1-CB 4.41Å; Y211-M388 HydrophobicContact CE1-CE 3.72Å; Y211-M388 HydrophobicContact CE1-SD 4.42Å; Y214-M388 HydrophobicContact CE1-CB 4.46Å; G384-M388 WeakPolarHBondContact O-CB 3.22Å; G384-M388 PolarHBondContact O-N 3.27Å; M388-W391 HydrophobicContact CE-CB 4.5Å; M388-W391 HydrophobicContact CE-CG 4.2Å; M388-W391 PolarHBondContact O-NE1 3.48Å
389	G	85.7	Confident	86.2	Confident	2 Å²	2	66.4 Å²	66.4	2%	0.021	29%	0.289	C	S	.	.			trans	84.9	173.1	-165.2	0	0	0	0	0	112	Y211 I385	Y211-G389 VanDerWaalsContact CE1-O 3.27Å; Y211-G389 WeakPolarHBondContact CE1-O 3.37Å; Y211-G389 PolarHBondContact OH-O 2.87Å; I385-G389 WeakPolarHBondContact O-CA 3.46Å; I385-G389 PolarHBondContact O-N 2.88Å
390	I	86.2	Confident	85.9	Confident	1 Å²	1	64.2 Å²	64.2	1%	0.005	28%	0.278	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.4	119.2	172.2	-56.3	-175.7	0	0	0	107.8	Y211 I385 L397 Y398 I400 F412 L413 I416	Y211-I390 WeakPolarHBondContact OH-CA 3.47Å; I385-I390 HydrophobicContact CG2-CG1 3.84Å; I390-L397 PolarHBondContact O-N 2.82Å; I390-Y398 HydrophobicContact CD1-CD2 4.37Å; I390-Y398 PolarHBondContact N-O 3.49Å; I390-Y398 PolarHBondContact O-N 2.96Å; I390-I400 HydrophobicContact CD1-CD1 3.89Å; I390-I400 HydrophobicContact CD1-CG1 4.21Å; I390-I400 HydrophobicContact CG1-CD1 3.99Å; I390-I400 HydrophobicContact CG1-CG1 4.16Å; I390-F412 HydrophobicContact CD1-CB 4.48Å; I390-F412 HydrophobicContact CD1-CD1 3.84Å; I390-F412 HydrophobicContact CG2-CD1 3.49Å; I390-F412 VanDerWaalsContact CG2-CD1 3.49Å; I390-F412 HydrophobicContact CG2-CE1 3.36Å; I390-L413 HydrophobicContact CD1-CB 4.45Å; I390-I416 HydrophobicContact CD1-CD1 4.31Å; I390-I416 HydrophobicContact CG1-CD1 4.4Å; I390-I416 HydrophobicContact CG2-CD1 3.94Å
391	W	82.9	Confident	85.2	Confident	107 Å²	107	65.8 Å²	65.8	41%	0.405	28%	0.284	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.7	140.1	-179.5	-75.6	62.9	0	0	0	109.5	Y211 M388 W394	Y211-W391 PolarHBondContact OH-N 3.07Å; Y211-W391 VanDerWaalsContact OH-N 3.08Å; M388-W391 HydrophobicContact CE-CB 4.5Å; M388-W391 HydrophobicContact CE-CG 4.2Å; M388-W391 PolarHBondContact O-NE1 3.48Å; W391-W394 WeakPolarHBondContact CZ3-O 3.42Å
392	F	78.1	Confident	84.6	Confident	127 Å²	127	68.8 Å²	68.8	56%	0.557	30%	0.303	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-123.4	109	167	-170.5	-107.6	0	0	0	107.3	W394 I395	F392-W394 PolarHBondContact O-N 3.47Å; F392-I395 PolarHBondContact N-O 2.9Å; F392-I395 PolarHBondContact O-N 3.37Å; F392-I395 VanDerWaalsContact O-N 3.07Å
393	F	76.8	Confident	84.2	Confident	172 Å²	172	72.6 Å²	72.6	75%	0.754	32%	0.319	S	S	*	.	T	Hydrogen-bonded Turn	trans	53.3	-106.9	-166.4	-58.9	-78.2	0	0	0	112.1
394	W	80.2	Confident	83.8	Confident	232 Å²	232	76.3 Å²	76.3	88%	0.879	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106.1	-0.3	-178.7	-99.7	-80.9	0	0	0	114.4	W391 F392	W391-W394 WeakPolarHBondContact CZ3-O 3.42Å; F392-W394 PolarHBondContact O-N 3.47Å
395	I	80.9	Confident	83.5	Confident	128 Å²	128	76.4 Å²	76.4	66%	0.656	33%	0.332	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-107.8	130.6	-176	-55.7	173.5	0	0	0	109.1	F392 L397	F392-I395 PolarHBondContact N-O 2.9Å; F392-I395 PolarHBondContact O-N 3.37Å; F392-I395 VanDerWaalsContact O-N 3.07Å; I395-L397 PolarHBondContact O-N 3.45Å
396	R	81.7	Confident	83.2	Confident	129 Å²	129	84 Å²	84	49%	0.487	36%	0.36	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.4	100.2	172.4	-173.2	179.7	69.5	-174.6	0.2	108.9
397	L	83.9	Confident	83.1	Confident	82 Å²	82	78.4 Å²	78.4	43%	0.429	34%	0.34	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-72.4	-49	-176.1	-171.1	69.7	0	0	0	111.9	I390 I395	I390-L397 PolarHBondContact O-N 2.82Å; I395-L397 PolarHBondContact O-N 3.45Å
398	Y	84.2	Confident	83.2	Confident	39 Å²	39	78.1 Å²	78.1	15%	0.153	34%	0.337	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-135.5	139.5	-179.1	-60.4	-65.4	0	0	0	111.9	Y120 I390 A409	Y120-Y398 PolarHBondContact OH-OH 2.86Å; I390-Y398 HydrophobicContact CD1-CD2 4.37Å; I390-Y398 PolarHBondContact N-O 3.49Å; I390-Y398 PolarHBondContact O-N 2.96Å; Y398-A409 HydrophobicContact CD1-CB 3.68Å; Y398-A409 HydrophobicContact CD2-CB 4.12Å; Y398-A409 HydrophobicContact CE1-CB 4.2Å; Y398-A409 HydrophobicContact CG-CB 3.63Å
399	K	83.9	Confident	83.4	Confident	69 Å²	69	75.2 Å²	75.2	30%	0.3	32%	0.324	S	S	.	.			trans	-104.1	119.2	169.3	-175.2	168.6	-179	165.3	0	109.3	R401 E525	K399-R401 HydrophobicContact CG-CG 4.31Å; K399-R401 PolarHBondContact O-N 3.23Å; K399-E525 IonicContact NZ-OE1 2.71Å; K399-E525 PolarHBondContact NZ-OE1 3.41Å; K399-E525 IonicContact NZ-OE2 3.48Å; K399-E525 PolarHBondContact NZ-OE2 3.47Å
400	I	84.6	Confident	83.6	Confident	8 Å²	8	75.2 Å²	75.2	4%	0.041	32%	0.323	C	S	.	.			trans	-84.5	118.1	-177.7	-53.4	-168.1	0	0	0	109.3	F35 I385 I390 L413	F35-I400 HydrophobicContact CD1-CG2 3.5Å; F35-I400 HydrophobicContact CE1-CG2 3.76Å; F35-I400 HydrophobicContact CG-CG2 4.43Å; I385-I400 HydrophobicContact CB-CD1 4.45Å; I385-I400 HydrophobicContact CG2-CD1 3.35Å; I385-I400 HydrophobicContact CG2-CG1 4.24Å; I390-I400 HydrophobicContact CD1-CD1 3.89Å; I390-I400 HydrophobicContact CD1-CG1 4.21Å; I390-I400 HydrophobicContact CG1-CD1 3.99Å; I390-I400 HydrophobicContact CG1-CG1 4.16Å; I400-L413 HydrophobicContact CD1-CB 3.92Å; I400-L413 HydrophobicContact CD1-CD1 3.5Å; I400-L413 HydrophobicContact CD1-CD2 3.73Å; I400-L413 HydrophobicContact CD1-CG 3.88Å; I400-L413 HydrophobicContact CG2-CD2 4.23Å
401	R	81.1	Confident	83.8	Confident	33 Å²	33	75.2 Å²	75.2	13%	0.125	32%	0.324	C	S	.	.			trans	-122	132.7	179	-62.9	-174.5	-173.6	167.4	-1.4	109.9	K399 K403 R404 T405 E525 D528	K399-R401 HydrophobicContact CG-CG 4.31Å; K399-R401 PolarHBondContact O-N 3.23Å; R401-K403 PolarHBondContact O-N 3.5Å; R401-R404 HydrophobicContact CB-CB 4.09Å; R401-R404 PolarHBondContact O-N 2.86Å; R401-T405 PolarHBondContact N-OG1 3.36Å; R401-T405 PolarHBondContact O-N 2.98Å; R401-T405 PolarHBondContact O-OG1 2.89Å; R401-E525 IonicContact CZ-OE2 2.83Å; R401-E525 IonicContact NH2-OE2 2.72Å; R401-E525 PolarHBondContact NH2-OE2 2.9Å; R401-D528 IonicContact CZ-OD1 3.66Å; R401-D528 IonicContact NH1-OD1 3.8Å; R401-D528 PolarHBondContact NH1-OD1 2.99Å; R401-D528 IonicContact NH1-OD2 2.83Å; R401-D528 PolarHBondContact NH1-OD2 3.43Å; R401-D528 IonicContact NH2-OD1 2.65Å; R401-D528 PolarHBondContact NH2-OD1 3.26Å
402	P	81.3	Confident	84.2	Confident	64 Å²	64	72.8 Å²	72.8	42%	0.416	32%	0.316	S	S	.	.	T	Hydrogen-bonded Turn	trans	-53.9	137.1	171.9	-22.4	33.1	0	0	0	110.5	F35 R404	F35-P402 HydrophobicContact CE1-CG 4.23Å; P402-R404 PolarHBondContact O-N 3.39Å
403	K	81.8	Confident	84.8	Confident	108 Å²	108	66.8 Å²	66.8	47%	0.47	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	57.5	5.4	179.1	-57.5	178.5	178.3	177.3	0	117.6	K34 Q36 S37 R38 R401	K34-K403 PolarHBondContact O-N 2.87Å; Q36-K403 CarbonylContact O-C 3.6Å; Q36-K403 WeakPolarHBondContact O-CA 3.36Å; S37-K403 WeakPolarHBondContact CA-O 3.07Å; R38-K403 PolarHBondContact N-O 3.34Å; R401-K403 PolarHBondContact O-N 3.5Å
404	R	82.3	Confident	85.6	Confident	89 Å²	89	58.7 Å²	58.7	34%	0.336	25%	0.254	S	S	.	.	T	Hydrogen-bonded Turn	trans	-134.5	14.6	-178.7	-68.1	-169.6	176.2	163.6	0.1	113	R401 P402 E523 E535	R401-R404 HydrophobicContact CB-CB 4.09Å; R401-R404 PolarHBondContact O-N 2.86Å; P402-R404 PolarHBondContact O-N 3.39Å; R404-E523 PolarHBondContact NH1-O 2.76Å; R404-E535 IonicContact NH2-OE2 3.65Å; R404-E535 PolarHBondContact NH2-OE2 3.06Å; R404-E535 VanDerWaalsContact NH2-OE2 3.16Å
405	T	85.9	Confident	86.2	Confident	2 Å²	2	49.4 Å²	49.4	1%	0.012	22%	0.221	C	C	.	.	B	Isolated β-bridge	trans	-83.8	122.5	178	-55.8	0	0	0	0	109.9	F35 S37 R401 A409 L410	F35-T405 WeakPolarHBondContact O-CB 3.39Å; F35-T405 PolarHBondContact O-N 3.23Å; F35-T405 VanDerWaalsContact O-N 3.13Å; F35-T405 PolarHBondContact O-OG1 3.46Å; S37-T405 WeakPolarHBondContact CB-O 3.28Å; S37-T405 PolarHBondContact N-O 3.44Å; R401-T405 PolarHBondContact N-OG1 3.36Å; R401-T405 PolarHBondContact O-N 2.98Å; R401-T405 PolarHBondContact O-OG1 2.89Å; T405-A409 HydrophobicContact CG2-CB 3.65Å; T405-L410 HydrophobicContact CG2-CB 4.3Å
406	R	85.9	Confident	86.8	Confident	160 Å²	160	44 Å²	44	60%	0.604	19%	0.193	S	C	*	.			trans	-60.2	149.8	175	-69.4	-174.5	177.6	162	2.2	111.4	Q408 A409 L410	R406-Q408 VanDerWaalsContact C-N 3.29Å; R406-Q408 PolarHBondContact O-N 3.46Å; R406-A409 PolarHBondContact O-N 2.95Å; R406-A409 VanDerWaalsContact O-N 3.13Å; R406-L410 PolarHBondContact O-N 3.29Å
407	P	87.3	Confident	87.4	Confident	5 Å²	5	37.9 Å²	37.9	3%	0.032	17%	0.17	C	C	.	.	H	α-helix	trans	-53.2	-39.2	-179.1	-31.7	38.7	0	0	0	115.2	D40 Y123 L410 L411	D40-P407 WeakPolarHBondContact O-CD 3.4Å; D40-P407 WeakPolarHBondContact O-CG 3.45Å; Y123-P407 HydrophobicContact CD1-CB 4.43Å; Y123-P407 HydrophobicContact CD2-CB 4.1Å; Y123-P407 HydrophobicContact CD2-CG 4.27Å; Y123-P407 HydrophobicContact CE1-CB 4.31Å; Y123-P407 HydrophobicContact CE1-CG 4.28Å; Y123-P407 HydrophobicContact CE2-CB 3.95Å; Y123-P407 HydrophobicContact CE2-CG 3.63Å; Y123-P407 HydrophobicContact CG-CB 4.33Å; P407-L410 WeakPolarHBondContact O-CB 3.28Å; P407-L410 PolarHBondContact O-N 3.06Å; P407-L411 WeakPolarHBondContact O-CG 3.37Å; P407-L411 PolarHBondContact O-N 2.88Å
408	Q	87.6	Confident	87.9	Confident	19 Å²	19	34 Å²	34	9%	0.089	15%	0.15	C	C	.	.	H	α-helix	trans	-62.4	-48	176.8	-69.6	166.3	-11	0	0	112.8	Y120 Y123 E124 R406 L410 L411 F412	Y120-Q408 HydrophobicContact CD2-CB 4.04Å; Y120-Q408 HydrophobicContact CD2-CG 4.14Å; Y120-Q408 HydrophobicContact CE2-CB 3.71Å; Y120-Q408 HydrophobicContact CE2-CG 3.99Å; Y123-Q408 HydrophobicContact CD1-CG 3.56Å; Y123-Q408 HydrophobicContact CE1-CG 4.16Å; Y123-Q408 HydrophobicContact CG-CG 4.45Å; E124-Q408 VanDerWaalsContact CA-NE2 3.33Å; E124-Q408 PolarHBondContact OE2-NE2 2.89Å; E124-Q408 PolarHBondContact OE2-OE1 3.08Å; R406-Q408 VanDerWaalsContact C-N 3.29Å; R406-Q408 PolarHBondContact O-N 3.46Å; Q408-L410 PolarHBondContact O-N 3.27Å; Q408-L411 PolarHBondContact O-N 2.91Å; Q408-F412 PolarHBondContact O-N 3.45Å
409	A	88.3	Confident	88.5	Confident	4 Å²	4	32.7 Å²	32.7	3%	0.033	15%	0.145	C	C	.	.	H	α-helix	trans	-63.8	-34.6	177.5	0	0	0	0	0	111.2	Y398 T405 R406 F412 L413	Y398-A409 HydrophobicContact CD1-CB 3.68Å; Y398-A409 HydrophobicContact CD2-CB 4.12Å; Y398-A409 HydrophobicContact CE1-CB 4.2Å; Y398-A409 HydrophobicContact CG-CB 3.63Å; T405-A409 HydrophobicContact CG2-CB 3.65Å; R406-A409 PolarHBondContact O-N 2.95Å; R406-A409 VanDerWaalsContact O-N 3.13Å; A409-F412 PolarHBondContact O-N 3.29Å; A409-L413 VanDerWaalsContact O-CB 3.29Å; A409-L413 WeakPolarHBondContact O-CB 3.45Å; A409-L413 PolarHBondContact O-N 3.37Å
410	L	89.8	Confident	89	Confident	2 Å²	2	29.4 Å²	29.4	1%	0.01	13%	0.131	C	C	.	.	H	α-helix	trans	-66.7	-42.2	174.6	-177.6	71.1	0	0	0	112.2	I32 F35 Q36 T46 A49 T405 R406 P407 Q408 L413 C414	I32-L410 HydrophobicContact CD1-CD1 3.9Å; I32-L410 HydrophobicContact CD1-CG 4.43Å; I32-L410 HydrophobicContact CG2-CD1 4.43Å; I32-L410 HydrophobicContact CG2-CD2 3.93Å; F35-L410 HydrophobicContact CB-CD1 4.18Å; Q36-L410 HydrophobicContact CB-CD2 4.49Å; T46-L410 HydrophobicContact CG2-CD2 4.36Å; A49-L410 HydrophobicContact CB-CD2 4.5Å; A49-L410 HydrophobicContact CB-CG 4.35Å; T405-L410 HydrophobicContact CG2-CB 4.3Å; R406-L410 PolarHBondContact O-N 3.29Å; P407-L410 WeakPolarHBondContact O-CB 3.28Å; P407-L410 PolarHBondContact O-N 3.06Å; Q408-L410 PolarHBondContact O-N 3.27Å; L410-L413 HydrophobicContact CD1-CD2 4.44Å; L410-L413 WeakPolarHBondContact O-CB 3.36Å; L410-L413 PolarHBondContact O-N 3.31Å; L410-C414 WeakPolarHBondContact O-CB 3.49Å; L410-C414 PolarHBondContact O-N 3.46Å
411	L	91.4	Very high	89.5	Confident	1 Å²	1	29 Å²	29	1%	0.005	13%	0.129	C	C	.	.	H	α-helix	trans	-63.7	-42.7	174.5	-70.9	169.6	0	0	0	111.3	T48 A49 I116 V119 P407 Q408 C414 M415	T48-L411 HydrophobicContact CG2-CD2 3.77Å; A49-L411 HydrophobicContact CB-CD2 4.47Å; I116-L411 HydrophobicContact CG2-CB 4.39Å; V119-L411 HydrophobicContact CB-CD1 4.31Å; V119-L411 HydrophobicContact CG1-CD1 3.84Å; V119-L411 HydrophobicContact CG1-CD2 4.43Å; P407-L411 WeakPolarHBondContact O-CG 3.37Å; P407-L411 PolarHBondContact O-N 2.88Å; Q408-L411 PolarHBondContact O-N 2.91Å; L411-C414 WeakPolarHBondContact O-CB 3.43Å; L411-C414 PolarHBondContact O-N 2.76Å; L411-M415 PolarHBondContact O-N 2.77Å
412	F	90.8	Very high	90	Very high	55 Å²	55	27.7 Å²	27.7	24%	0.241	13%	0.125	C	C	.	.	H	α-helix	trans	-66.5	-40.9	177.4	-158.1	-96.7	0	0	0	112.1	I390 Q408 A409 C414 M415 I416	I390-F412 HydrophobicContact CD1-CB 4.48Å; I390-F412 HydrophobicContact CD1-CD1 3.84Å; I390-F412 HydrophobicContact CG2-CD1 3.49Å; I390-F412 VanDerWaalsContact CG2-CD1 3.49Å; I390-F412 HydrophobicContact CG2-CE1 3.36Å; Q408-F412 PolarHBondContact O-N 3.45Å; A409-F412 PolarHBondContact O-N 3.29Å; F412-C414 VanDerWaalsContact C-N 3.33Å; F412-C414 PolarHBondContact O-N 3.01Å; F412-M415 HydrophobicContact CD2-CE 3.81Å; F412-M415 HydrophobicContact CE2-CE 3.53Å; F412-M415 HydrophobicContact CZ-CE 4.04Å; F412-M415 PolarHBondContact O-N 3.33Å; F412-I416 HydrophobicContact CD1-CD1 3.62Å; F412-I416 HydrophobicContact CD1-CG1 4.2Å; F412-I416 HydrophobicContact CE1-CD1 3.6Å; F412-I416 HydrophobicContact CE1-CG1 4.16Å; F412-I416 WeakPolarHBondContact O-CG1 3.46Å; F412-I416 PolarHBondContact O-N 2.97Å
413	L	91.9	Very high	90.7	Very high	2 Å²	2	24.8 Å²	24.8	1%	0.01	11%	0.106	C	C	.	.	H	α-helix	trans	-56.6	-47.1	170.5	169.8	60.6	0	0	0	111.2	Y31 I385 I390 I400 A409 L410 M415 I416 L417	Y31-L413 HydrophobicContact CE1-CD2 4.45Å; Y31-L413 VanDerWaalsContact OH-CD2 3.23Å; Y31-L413 WeakPolarHBondContact OH-CD2 3.38Å; I385-L413 HydrophobicContact CD1-CD1 3.77Å; I385-L413 HydrophobicContact CG2-CD1 4.17Å; I390-L413 HydrophobicContact CD1-CB 4.45Å; I400-L413 HydrophobicContact CD1-CB 3.92Å; I400-L413 HydrophobicContact CD1-CD1 3.5Å; I400-L413 HydrophobicContact CD1-CD2 3.73Å; I400-L413 HydrophobicContact CD1-CG 3.88Å; I400-L413 HydrophobicContact CG2-CD2 4.23Å; A409-L413 VanDerWaalsContact O-CB 3.29Å; A409-L413 WeakPolarHBondContact O-CB 3.45Å; A409-L413 PolarHBondContact O-N 3.37Å; L410-L413 HydrophobicContact CD1-CD2 4.44Å; L410-L413 WeakPolarHBondContact O-CB 3.36Å; L410-L413 PolarHBondContact O-N 3.31Å; L413-M415 VanDerWaalsContact C-N 3.32Å; L413-M415 PolarHBondContact O-N 3.34Å; L413-I416 PolarHBondContact O-N 2.91Å; L413-L417 HydrophobicContact CD1-CD1 3.82Å; L413-L417 HydrophobicContact CD1-CG 4.01Å; L413-L417 HydrophobicContact CG-CD1 4.02Å; L413-L417 WeakPolarHBondContact O-CB 3.32Å; L413-L417 WeakPolarHBondContact O-CG 3.32Å; L413-L417 PolarHBondContact O-N 2.95Å
414	C	92.5	Very high	91.2	Very high	1 Å²	1	19.7 Å²	19.7	1%	0.007	8%	0.083	C	C	.	.	H	α-helix	trans	-62.6	-40.3	178.4	-173.2	0	0	0	0	112	A49 L410 L411 F412 L417 L418	A49-C414 HydrophobicContact CB-CB 4.13Å; A49-C414 PolarHBondContact O-SG 3.49Å; L410-C414 WeakPolarHBondContact O-CB 3.49Å; L410-C414 PolarHBondContact O-N 3.46Å; L411-C414 WeakPolarHBondContact O-CB 3.43Å; L411-C414 PolarHBondContact O-N 2.76Å; F412-C414 VanDerWaalsContact C-N 3.33Å; F412-C414 PolarHBondContact O-N 3.01Å; C414-L417 PolarHBondContact O-N 2.96Å; C414-L418 WeakPolarHBondContact O-CB 3.32Å; C414-L418 PolarHBondContact O-N 3.2Å
415	M	93.1	Very high	91.5	Very high	37 Å²	37	15.6 Å²	15.6	18%	0.182	7%	0.069	C	C	.	.	H	α-helix	trans	-62.1	-47.2	175.7	-171.5	-174.7	74.3	0	0	111.2	I116 L411 F412 L413 L417 L418 L419	I116-M415 HydrophobicContact CD1-CB 4.45Å; L411-M415 PolarHBondContact O-N 2.77Å; F412-M415 HydrophobicContact CD2-CE 3.81Å; F412-M415 HydrophobicContact CE2-CE 3.53Å; F412-M415 HydrophobicContact CZ-CE 4.04Å; F412-M415 PolarHBondContact O-N 3.33Å; L413-M415 VanDerWaalsContact C-N 3.32Å; L413-M415 PolarHBondContact O-N 3.34Å; M415-L417 PolarHBondContact O-N 2.96Å; M415-L418 PolarHBondContact O-N 3.16Å; M415-L419 WeakPolarHBondContact O-CG 3.4Å; M415-L419 PolarHBondContact O-N 3.26Å
416	I	94.2	Very high	91.7	Very high	15 Å²	15	15.6 Å²	15.6	8%	0.077	7%	0.068	C	C	.	.	H	α-helix	trans	-59.9	-46.7	176.1	-68.6	170.1	0	0	0	110.8	A207 Y211 I385 I390 F412 L413 L418 L419 I420	A207-I416 HydrophobicContact CB-CG2 4.21Å; Y211-I416 HydrophobicContact CD2-CG2 4.19Å; Y211-I416 HydrophobicContact CE2-CD1 4.45Å; Y211-I416 HydrophobicContact CE2-CG2 4.34Å; I385-I416 HydrophobicContact CD1-CG2 3.83Å; I390-I416 HydrophobicContact CD1-CD1 4.31Å; I390-I416 HydrophobicContact CG1-CD1 4.4Å; I390-I416 HydrophobicContact CG2-CD1 3.94Å; F412-I416 HydrophobicContact CD1-CD1 3.62Å; F412-I416 HydrophobicContact CD1-CG1 4.2Å; F412-I416 HydrophobicContact CE1-CD1 3.6Å; F412-I416 HydrophobicContact CE1-CG1 4.16Å; F412-I416 WeakPolarHBondContact O-CG1 3.46Å; F412-I416 PolarHBondContact O-N 2.97Å; L413-I416 PolarHBondContact O-N 2.91Å; I416-L418 VanDerWaalsContact C-N 3.33Å; I416-L418 PolarHBondContact O-N 2.9Å; I416-L419 PolarHBondContact O-N 2.59Å; I416-I420 HydrophobicContact CG2-CD1 3.73Å; I416-I420 HydrophobicContact CG2-CG1 4.28Å; I416-I420 WeakPolarHBondContact O-CB 3.41Å; I416-I420 VanDerWaalsContact O-CG1 3.31Å; I416-I420 WeakPolarHBondContact O-CG1 3.41Å; I416-I420 PolarHBondContact O-N 2.99Å
417	L	93.7	Very high	91.9	Very high	0 Å²	0	8 Å²	8	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-63.4	-38.7	179.6	-71.9	172.8	0	0	0	112.2	Y31 L53 M382 I385 L413 C414 M415 I420 V421	Y31-L417 HydrophobicContact CE1-CD1 3.65Å; Y31-L417 WeakPolarHBondContact OH-CD1 3.39Å; L53-L417 HydrophobicContact CD1-CB 3.94Å; L53-L417 HydrophobicContact CD1-CD1 4.44Å; M382-L417 HydrophobicContact CG-CD1 4.21Å; M382-L417 HydrophobicContact CG-CD2 3.84Å; I385-L417 HydrophobicContact CD1-CD2 4.08Å; I385-L417 HydrophobicContact CD1-CG 4.45Å; L413-L417 HydrophobicContact CD1-CD1 3.82Å; L413-L417 HydrophobicContact CD1-CG 4.01Å; L413-L417 HydrophobicContact CG-CD1 4.02Å; L413-L417 WeakPolarHBondContact O-CB 3.32Å; L413-L417 WeakPolarHBondContact O-CG 3.32Å; L413-L417 PolarHBondContact O-N 2.95Å; C414-L417 PolarHBondContact O-N 2.96Å; M415-L417 PolarHBondContact O-N 2.96Å; L417-I420 PolarHBondContact O-N 3.07Å; L417-V421 VanDerWaalsContact O-CG2 3.31Å; L417-V421 WeakPolarHBondContact O-CG2 3.34Å; L417-V421 PolarHBondContact O-N 3.26Å
418	L	95.1	Very high	92.1	Very high	1 Å²	1	8 Å²	8	1%	0.005	4%	0.039	C	C	.	.	H	α-helix	trans	-59.4	-46.9	173.4	174.6	160.3	0	0	0	111	A52 A56 I108 V112 C414 M415 I416 I420 V421 L422	A52-L418 HydrophobicContact CB-CD1 4.38Å; A56-L418 HydrophobicContact CB-CB 4.08Å; A56-L418 HydrophobicContact CB-CD1 4.45Å; A56-L418 HydrophobicContact CB-CG 3.88Å; I108-L418 HydrophobicContact CG2-CD2 3.96Å; V112-L418 HydrophobicContact CG2-CD1 4.2Å; V112-L418 HydrophobicContact CG2-CD2 3.66Å; C414-L418 WeakPolarHBondContact O-CB 3.32Å; C414-L418 PolarHBondContact O-N 3.2Å; M415-L418 PolarHBondContact O-N 3.16Å; I416-L418 VanDerWaalsContact C-N 3.33Å; I416-L418 PolarHBondContact O-N 2.9Å; L418-I420 VanDerWaalsContact C-N 3.33Å; L418-I420 PolarHBondContact O-N 3.3Å; L418-V421 PolarHBondContact O-N 2.9Å; L418-L422 WeakPolarHBondContact O-CB 3.48Å; L418-L422 PolarHBondContact O-N 3.31Å
419	L	95.2	Very high	92.1	Very high	11 Å²	11	7.3 Å²	7.3	6%	0.058	4%	0.036	C	C	.	.	H	α-helix	trans	-64.7	-38.1	178.1	-64.7	173	0	0	0	112.1	L200 I203 G204 M415 I416 L422 H423	L200-L419 HydrophobicContact CB-CD2 3.98Å; L200-L419 HydrophobicContact CD2-CD2 4.02Å; L200-L419 HydrophobicContact CG-CD2 4.44Å; I203-L419 HydrophobicContact CB-CD1 4.42Å; I203-L419 HydrophobicContact CG2-CD1 3.82Å; G204-L419 WeakPolarHBondContact CA-O 3.34Å; M415-L419 WeakPolarHBondContact O-CG 3.4Å; M415-L419 PolarHBondContact O-N 3.26Å; I416-L419 PolarHBondContact O-N 2.59Å; L419-L422 PolarHBondContact O-N 2.95Å; L419-H423 PolarHBondContact O-N 3.46Å
420	I	95.6	Very high	92	Very high	0 Å²	0	7.1 Å²	7.1	0%	0	3%	0.034	C	C	.	.	H	α-helix	trans	-62	-47.5	174.1	-75.2	175.4	0	0	0	111	A207 V208 S381 I385 I416 L417 L418 L422 H423 T424	A207-I420 HydrophobicContact CB-CD1 4.14Å; A207-I420 HydrophobicContact CB-CG1 3.71Å; V208-I420 HydrophobicContact CG2-CB 4.14Å; V208-I420 HydrophobicContact CG2-CG1 3.96Å; V208-I420 HydrophobicContact CG2-CG2 3.92Å; S381-I420 WeakPolarHBondContact OG-CG2 3.22Å; I385-I420 HydrophobicContact CD1-CD1 4.42Å; I416-I420 HydrophobicContact CG2-CD1 3.73Å; I416-I420 HydrophobicContact CG2-CG1 4.28Å; I416-I420 WeakPolarHBondContact O-CB 3.41Å; I416-I420 VanDerWaalsContact O-CG1 3.31Å; I416-I420 WeakPolarHBondContact O-CG1 3.41Å; I416-I420 PolarHBondContact O-N 2.99Å; L417-I420 PolarHBondContact O-N 3.07Å; L418-I420 VanDerWaalsContact C-N 3.33Å; L418-I420 PolarHBondContact O-N 3.3Å; I420-L422 VanDerWaalsContact C-N 3.31Å; I420-L422 PolarHBondContact O-N 2.82Å; I420-H423 PolarHBondContact O-N 2.73Å; I420-T424 WeakPolarHBondContact O-CB 3.37Å; I420-T424 PolarHBondContact O-N 3.4Å; I420-T424 PolarHBondContact O-OG1 3.14Å
421	V	94	Very high	92	Very high	1 Å²	1	7.1 Å²	7.1	1%	0.006	3%	0.034	C	C	.	.	H	α-helix	trans	-61.8	-42.9	178.1	171.3	0	0	0	0	110.4	A56 L57 V378 L417 L418 H423 T424 S425	A56-V421 HydrophobicContact CB-CB 4.18Å; A56-V421 HydrophobicContact CB-CG1 4.12Å; A56-V421 VanDerWaalsContact O-CG1 3.3Å; A56-V421 WeakPolarHBondContact O-CG1 3.31Å; L57-V421 HydrophobicContact CD2-CG1 4.42Å; L57-V421 HydrophobicContact CD2-CG2 3.97Å; V378-V421 HydrophobicContact CG2-CG2 3.54Å; L417-V421 VanDerWaalsContact O-CG2 3.31Å; L417-V421 WeakPolarHBondContact O-CG2 3.34Å; L417-V421 PolarHBondContact O-N 3.26Å; L418-V421 PolarHBondContact O-N 2.9Å; V421-H423 PolarHBondContact O-N 3.08Å; V421-T424 WeakPolarHBondContact O-CB 3.39Å; V421-T424 PolarHBondContact O-N 3.34Å; V421-T424 VanDerWaalsContact O-N 3.1Å; V421-S425 PolarHBondContact O-N 3.36Å; V421-S425 VanDerWaalsContact O-N 3.1Å; V421-S425 PolarHBondContact O-OG 3.39Å
422	L	93	Very high	91.9	Very high	4 Å²	4	7.1 Å²	7.1	2%	0.021	3%	0.034	C	C	.	.	H	α-helix	trans	-60.1	-45.9	177.6	-168.7	69.7	0	0	0	111.8	Y105 I108 I197 L200 T201 L418 L419 I420 T424 S425	Y105-L422 HydrophobicContact CD1-CD1 4.06Å; Y105-L422 HydrophobicContact CE1-CD1 3.59Å; I108-L422 HydrophobicContact CD1-CD1 4.39Å; I197-L422 HydrophobicContact CG2-CD1 4.1Å; I197-L422 HydrophobicContact CG2-CD2 4.25Å; I197-L422 HydrophobicContact CG2-CG 4.47Å; L200-L422 HydrophobicContact CB-CD2 3.71Å; T201-L422 HydrophobicContact CG2-CB 4.4Å; T201-L422 HydrophobicContact CG2-CD2 3.8Å; T201-L422 HydrophobicContact CG2-CG 3.55Å; L418-L422 WeakPolarHBondContact O-CB 3.48Å; L418-L422 PolarHBondContact O-N 3.31Å; L419-L422 PolarHBondContact O-N 2.95Å; I420-L422 VanDerWaalsContact C-N 3.31Å; I420-L422 PolarHBondContact O-N 2.82Å; L422-T424 VanDerWaalsContact C-N 3.34Å; L422-S425 PolarHBondContact O-N 3.02Å
423	H	94.5	Very high	91.6	Very high	4 Å²	4	4.8 Å²	4.8	2%	0.019	3%	0.025	C	C	.	.	H	α-helix	trans	-68.5	-32.3	173.7	-176.5	73.6	0	0	0	112.6	T201 M205 V208 L419 I420 V421 S425 Y426 M427	T201-H423 PolarHBondContact O-ND1 3.47Å; M205-H423 VanDerWaalsContact CB-CE1 3.46Å; M205-H423 WeakPolarHBondContact CB-CE1 3.37Å; V208-H423 HydrophobicContact CG2-CB 4.29Å; L419-H423 PolarHBondContact O-N 3.46Å; I420-H423 PolarHBondContact O-N 2.73Å; V421-H423 PolarHBondContact O-N 3.08Å; H423-S425 PolarHBondContact O-N 3.27Å; H423-Y426 AromaticContact CE1-CD1 3.92Å; H423-Y426 WeakPolarHBondContact O-CA 3.39Å; H423-Y426 WeakPolarHBondContact O-CB 3.42Å; H423-Y426 PolarHBondContact O-N 2.94Å; H423-M427 PolarHBondContact O-N 3.3Å
424	T	92.4	Very high	91.3	Very high	0 Å²	0	5.3 Å²	5.3	0%	0	3%	0.027	C	C	.	.	H	α-helix	trans	-60.1	-37.7	176.7	-58.6	0	0	0	0	110.9	F377 I420 V421 L422 Y426 M427 I428	F377-T424 HydrophobicContact CB-CG2 3.92Å; F377-T424 HydrophobicContact CD2-CG2 3.62Å; F377-T424 HydrophobicContact CE2-CG2 4.46Å; F377-T424 HydrophobicContact CG-CG2 3.99Å; I420-T424 WeakPolarHBondContact O-CB 3.37Å; I420-T424 PolarHBondContact O-N 3.4Å; I420-T424 PolarHBondContact O-OG1 3.14Å; V421-T424 WeakPolarHBondContact O-CB 3.39Å; V421-T424 PolarHBondContact O-N 3.34Å; V421-T424 VanDerWaalsContact O-N 3.1Å; L422-T424 VanDerWaalsContact C-N 3.34Å; T424-Y426 VanDerWaalsContact C-N 3.27Å; T424-Y426 PolarHBondContact O-N 2.87Å; T424-M427 HydrophobicContact CG2-CE 4.26Å; T424-M427 PolarHBondContact O-N 3.45Å; T424-M427 VanDerWaalsContact O-N 3.1Å; T424-I428 HydrophobicContact CG2-CD1 4.25Å; T424-I428 HydrophobicContact CG2-CG1 4.42Å; T424-I428 VanDerWaalsContact O-CG1 3.29Å; T424-I428 WeakPolarHBondContact O-CG1 3.21Å; T424-I428 PolarHBondContact O-N 2.79Å
425	S	89.4	Confident	91.1	Very high	4 Å²	4	5.2 Å²	5.2	3%	0.028	3%	0.027	C	C	.	.	H	α-helix	trans	-58.2	-38.7	173.5	-54	0	0	0	0	112.5	V421 L422 H423	V421-S425 PolarHBondContact O-N 3.36Å; V421-S425 VanDerWaalsContact O-N 3.1Å; V421-S425 PolarHBondContact O-OG 3.39Å; L422-S425 PolarHBondContact O-N 3.02Å; H423-S425 PolarHBondContact O-N 3.27Å
426	Y	89.2	Confident	90.9	Very high	2 Å²	2	3.6 Å²	3.6	1%	0.008	2%	0.019	C	C	.	.	H	α-helix	trans	-69.6	-43.4	171.5	174.5	-85.3	0	0	0	112.2	H423 T424 I428 Y429 S430 L483 H484 Y493	H423-Y426 AromaticContact CE1-CD1 3.92Å; H423-Y426 WeakPolarHBondContact O-CA 3.39Å; H423-Y426 WeakPolarHBondContact O-CB 3.42Å; H423-Y426 PolarHBondContact O-N 2.94Å; T424-Y426 VanDerWaalsContact C-N 3.27Å; T424-Y426 PolarHBondContact O-N 2.87Å; Y426-I428 PolarHBondContact O-N 3.16Å; Y426-Y429 WeakPolarHBondContact O-CB 3.46Å; Y426-Y429 PolarHBondContact O-N 2.84Å; Y426-S430 PolarHBondContact O-N 3.04Å; Y426-L483 HydrophobicContact CD2-CB 4.47Å; Y426-H484 AromaticContact CD2-CE1 3.96Å; Y426-H484 AromaticContact CD2-NE2 3.76Å; Y426-H484 AromaticContact CE2-CE1 3.1Å; Y426-H484 WeakPolarHBondContact CE2-CE1 3.48Å; Y426-H484 AromaticContact CE2-ND1 3.89Å; Y426-H484 AromaticContact CE2-NE2 3.37Å; Y426-H484 WeakPolarHBondContact CE2-NE2 3.07Å; Y426-H484 AromaticContact CZ-CE1 3.73Å; Y426-Y493 HydrophobicContact CD1-CD2 4.16Å; Y426-Y493 HydrophobicContact CD1-CG 4.11Å; Y426-Y493 AromaticContact CD2-CD2 3.71Å; Y426-Y493 HydrophobicContact CD2-CD2 3.71Å; Y426-Y493 AromaticContact CD2-CE2 3.92Å; Y426-Y493 HydrophobicContact CD2-CE2 3.92Å; Y426-Y493 HydrophobicContact CD2-CG 4.45Å; Y426-Y493 AromaticContact CE1-CD2 3.77Å; Y426-Y493 HydrophobicContact CE1-CD2 3.77Å; Y426-Y493 AromaticContact CE1-CG 3.67Å; Y426-Y493 HydrophobicContact CE1-CG 3.67Å; Y426-Y493 AromaticContact CE2-CD2 3.16Å; Y426-Y493 HydrophobicContact CE2-CD2 3.16Å; Y426-Y493 AromaticContact CE2-CE2 3.75Å; Y426-Y493 HydrophobicContact CE2-CE2 3.75Å; Y426-Y493 AromaticContact CE2-CG 3.97Å; Y426-Y493 HydrophobicContact CE2-CG 3.97Å; Y426-Y493 HydrophobicContact CG-CD2 4.17Å; Y426-Y493 HydrophobicContact CG-CE2 4.47Å; Y426-Y493 AromaticContact CZ-CD2 3.24Å; Y426-Y493 AromaticContact CZ-CG 3.6Å; Y426-Y493 VanDerWaalsContact OH-CB 3.26Å; Y426-Y493 WeakPolarHBondContact OH-CB 3.3Å
427	M	91.3	Very high	90.5	Very high	1 Å²	1	3.6 Å²	3.6	1%	0.005	2%	0.018	C	C	.	.	H	α-helix	trans	-62.8	-32.4	-178	-172.7	173.4	53.9	0	0	112.1	V208 F377 H423 T424 Y429 S430 L431 F500	V208-M427 HydrophobicContact CG1-CE 4.37Å; V208-M427 HydrophobicContact CG1-SD 4.22Å; F377-M427 HydrophobicContact CD1-CE 3.5Å; F377-M427 VanDerWaalsContact CD1-CE 3.5Å; F377-M427 HydrophobicContact CD2-CE 3.81Å; F377-M427 HydrophobicContact CE1-CE 3.26Å; F377-M427 HydrophobicContact CE1-SD 4.2Å; F377-M427 HydrophobicContact CE2-CE 3.59Å; F377-M427 HydrophobicContact CG-CE 3.77Å; F377-M427 HydrophobicContact CZ-CE 3.32Å; F377-M427 HydrophobicContact CZ-SD 4.21Å; H423-M427 PolarHBondContact O-N 3.3Å; T424-M427 HydrophobicContact CG2-CE 4.26Å; T424-M427 PolarHBondContact O-N 3.45Å; T424-M427 VanDerWaalsContact O-N 3.1Å; M427-Y429 VanDerWaalsContact C-N 3.26Å; M427-Y429 PolarHBondContact O-N 3.47Å; M427-S430 CarbonylContact O-C 3.42Å; M427-S430 PolarHBondContact O-N 2.9Å; M427-L431 HydrophobicContact CG-CD1 4.39Å; M427-L431 WeakPolarHBondContact O-CB 3.25Å; M427-L431 WeakPolarHBondContact O-CG 3.5Å; M427-L431 PolarHBondContact O-N 3.04Å; M427-F500 HydrophobicContact SD-CZ 4.35Å
428	I	90.5	Very high	90.1	Very high	3 Å²	3	4.3 Å²	4.3	2%	0.015	2%	0.021	C	C	.	.	H	α-helix	trans	-59.2	-36.6	174	-68.2	164.6	0	0	0	111.4	L63 I370 T424 Y426 L431 A432 V436	L63-I428 HydrophobicContact CD2-CB 4.13Å; L63-I428 HydrophobicContact CD2-CD1 3.82Å; L63-I428 HydrophobicContact CD2-CG2 3.86Å; I370-I428 HydrophobicContact CD1-CG2 3.97Å; I370-I428 HydrophobicContact CG2-CD1 4.4Å; T424-I428 HydrophobicContact CG2-CD1 4.25Å; T424-I428 HydrophobicContact CG2-CG1 4.42Å; T424-I428 VanDerWaalsContact O-CG1 3.29Å; T424-I428 WeakPolarHBondContact O-CG1 3.21Å; T424-I428 PolarHBondContact O-N 2.79Å; Y426-I428 PolarHBondContact O-N 3.16Å; I428-L431 WeakPolarHBondContact O-CB 3.16Å; I428-L431 PolarHBondContact O-N 3.07Å; I428-A432 PolarHBondContact O-N 2.96Å; I428-V436 HydrophobicContact CG2-CG2 3.78Å
429	Y	87.4	Confident	89.7	Confident	6 Å²	6	4.2 Å²	4.2	2%	0.024	2%	0.021	C	C	.	.	H	α-helix	trans	-63.9	-43.8	171.5	166.7	-101.5	0	0	0	112	Y426 M427 L431 A432 P433 V436 M437 Y480 H484	Y426-Y429 WeakPolarHBondContact O-CB 3.46Å; Y426-Y429 PolarHBondContact O-N 2.84Å; M427-Y429 VanDerWaalsContact C-N 3.26Å; M427-Y429 PolarHBondContact O-N 3.47Å; Y429-L431 PolarHBondContact O-N 3.44Å; Y429-A432 CarbonylContact O-C 3.54Å; Y429-A432 PolarHBondContact O-N 3.03Å; Y429-P433 HydrophobicContact CD2-CB 4.13Å; Y429-P433 HydrophobicContact CE2-CB 3.65Å; Y429-P433 WeakPolarHBondContact O-CA 3.14Å; Y429-P433 WeakPolarHBondContact O-CB 3.28Å; Y429-P433 WeakPolarHBondContact O-CD 3.5Å; Y429-V436 HydrophobicContact CD2-CB 4.3Å; Y429-V436 HydrophobicContact CD2-CG1 4.31Å; Y429-M437 HydrophobicContact CD2-CG 4.17Å; Y429-M437 HydrophobicContact CE2-CG 3.62Å; Y429-M437 HydrophobicContact CE2-SD 3.6Å; Y429-Y480 AromaticContact CD2-CD2 3.86Å; Y429-Y480 HydrophobicContact CD2-CD2 3.86Å; Y429-Y480 HydrophobicContact CD2-CE2 4.19Å; Y429-Y480 HydrophobicContact CE1-CE2 4.27Å; Y429-Y480 AromaticContact CE2-CD2 3.66Å; Y429-Y480 HydrophobicContact CE2-CD2 3.66Å; Y429-Y480 AromaticContact CE2-CE2 3.53Å; Y429-Y480 HydrophobicContact CE2-CE2 3.53Å; Y429-Y480 HydrophobicContact CG-CD2 4.49Å; Y429-Y480 AromaticContact CZ-CE2 3.55Å; Y429-H484 AromaticContact CD1-CE1 3.37Å; Y429-H484 WeakPolarHBondContact CD1-CE1 2.96Å; Y429-H484 AromaticContact CD1-NE2 3.11Å; Y429-H484 WeakPolarHBondContact CD1-NE2 3.14Å; Y429-H484 AromaticContact CE1-CE1 3.3Å; Y429-H484 WeakPolarHBondContact CE1-CE1 3.5Å; Y429-H484 AromaticContact CE1-NE2 3.43Å; Y429-H484 WeakPolarHBondContact CE1-NE2 3.4Å; Y429-H484 AromaticContact CG-NE2 3.64Å
430	S	87.9	Confident	89.3	Confident	0 Å²	0	5.9 Å²	5.9	0%	0	3%	0.034	C	C	.	.	H	α-helix	trans	-66.2	-24.9	176.9	-66.1	0	0	0	0	112.9	S326 Y426 M427 N497	S326-S430 WeakPolarHBondContact CB-O 3.23Å; S326-S430 PolarHBondContact OG-O 3.44Å; Y426-S430 PolarHBondContact O-N 3.04Å; M427-S430 CarbonylContact O-C 3.42Å; M427-S430 PolarHBondContact O-N 2.9Å; S430-N497 WeakPolarHBondContact CB-ND2 3.22Å; S430-N497 PolarHBondContact OG-ND2 3.3Å; S430-N497 VanDerWaalsContact OG-ND2 3.13Å
431	L	89.6	Confident	89	Confident	2 Å²	2	6 Å²	6	1%	0.01	3%	0.034	C	C	.	.	H	α-helix	trans	-79.2	-34.7	177.1	-85.7	170.1	0	0	0	113.5	F319 L323 N350 L352 F377 M427 I428 Y429	F319-L431 HydrophobicContact CB-CD2 4.11Å; F319-L431 HydrophobicContact CD1-CD1 4.36Å; F319-L431 HydrophobicContact CD1-CD2 3.96Å; F319-L431 HydrophobicContact CG-CD2 4.36Å; L323-L431 HydrophobicContact CD1-CD2 4.33Å; L323-L431 HydrophobicContact CD2-CD2 3.87Å; L323-L431 HydrophobicContact CD2-CG 3.81Å; L323-L431 HydrophobicContact CG-CD2 3.59Å; L323-L431 HydrophobicContact CG-CG 4.08Å; N350-L431 PolarHBondContact ND2-O 3.44Å; L352-L431 HydrophobicContact CD2-CB 3.87Å; L352-L431 HydrophobicContact CD2-CD1 4.35Å; L352-L431 HydrophobicContact CD2-CD2 3.85Å; L352-L431 HydrophobicContact CD2-CG 4.25Å; F377-L431 HydrophobicContact CE2-CD1 3.82Å; F377-L431 HydrophobicContact CZ-CD1 3.91Å; M427-L431 HydrophobicContact CG-CD1 4.39Å; M427-L431 WeakPolarHBondContact O-CB 3.25Å; M427-L431 WeakPolarHBondContact O-CG 3.5Å; M427-L431 PolarHBondContact O-N 3.04Å; I428-L431 WeakPolarHBondContact O-CB 3.16Å; I428-L431 PolarHBondContact O-N 3.07Å; Y429-L431 PolarHBondContact O-N 3.44Å
432	A	88.2	Confident	88.7	Confident	1 Å²	1	9.6 Å²	9.6	1%	0.008	5%	0.05	C	C	.	.			trans	-150.9	72.6	-177.6	0	0	0	0	0	111	N353 L356 I428 Y429 Q434 Y435 V436	N353-A432 HydrophobicContact CB-CB 4.05Å; L356-A432 HydrophobicContact CD1-CB 3.7Å; I428-A432 PolarHBondContact O-N 2.96Å; Y429-A432 CarbonylContact O-C 3.54Å; Y429-A432 PolarHBondContact O-N 3.03Å; A432-Q434 PolarHBondContact O-N 3.37Å; A432-Y435 PolarHBondContact O-N 3.04Å; A432-V436 VanDerWaalsContact O-CG2 3.31Å; A432-V436 WeakPolarHBondContact O-CG2 3.42Å; A432-V436 PolarHBondContact O-N 3.35Å
433	P	85.4	Confident	88.6	Confident	5 Å²	5	10.1 Å²	10.1	3%	0.032	5%	0.051	C	C	.	.	H	α-helix	trans	-63.3	-41	-168.1	22.5	-33	0	0	0	112.9	T346 Y429 V436 M437	T346-P433 HydrophobicContact CG2-CG 4.02Å; Y429-P433 HydrophobicContact CD2-CB 4.13Å; Y429-P433 HydrophobicContact CE2-CB 3.65Å; Y429-P433 WeakPolarHBondContact O-CA 3.14Å; Y429-P433 WeakPolarHBondContact O-CB 3.28Å; Y429-P433 WeakPolarHBondContact O-CD 3.5Å; P433-V436 PolarHBondContact O-N 3.36Å; P433-M437 WeakPolarHBondContact O-CB 3.31Å; P433-M437 WeakPolarHBondContact O-CG 3.32Å; P433-M437 PolarHBondContact O-N 3.15Å
434	Q	85.4	Confident	88.2	Confident	13 Å²	13	12.6 Å²	12.6	6%	0.061	7%	0.065	C	C	.	.	H	α-helix	trans	-66.9	-47.4	-178.5	-178.6	61.2	22.5	0	0	111.7	T346 N353 L357 A432 V436 Y438 G439 I464 C465	T346-Q434 HydrophobicContact CG2-CB 3.99Å; N353-Q434 WeakPolarHBondContact OD1-CB 3.47Å; N353-Q434 PolarHBondContact OD1-N 2.92Å; L357-Q434 HydrophobicContact CD1-CG 4.22Å; A432-Q434 PolarHBondContact O-N 3.37Å; Q434-V436 VanDerWaalsContact C-N 3.35Å; Q434-V436 PolarHBondContact O-N 3.39Å; Q434-Y438 PolarHBondContact O-N 3.43Å; Q434-G439 PolarHBondContact O-N 3.38Å; Q434-I464 VanDerWaalsContact NE2-CG2 3.32Å; Q434-C465 PolarHBondContact NE2-O 2.67Å
435	Y	88.1	Confident	87.7	Confident	0 Å²	0	13.3 Å²	13.3	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-60.6	-42.2	175.7	171	-98.5	0	0	0	112.2	I67 N353 L356 L357 Q360 D366 I370 A432 G439	I67-Y435 HydrophobicContact CD1-CD1 4.16Å; I67-Y435 HydrophobicContact CD1-CE1 3.61Å; I67-Y435 HydrophobicContact CG2-CE1 4.25Å; I67-Y435 HydrophobicContact CG2-CE2 4.04Å; N353-Y435 PolarHBondContact OD1-N 3.44Å; L356-Y435 HydrophobicContact CB-CD1 3.97Å; L356-Y435 HydrophobicContact CB-CD2 3.65Å; L356-Y435 HydrophobicContact CB-CE1 4.25Å; L356-Y435 HydrophobicContact CB-CE2 3.94Å; L356-Y435 HydrophobicContact CB-CG 3.66Å; L356-Y435 HydrophobicContact CD1-CD1 3.78Å; L356-Y435 HydrophobicContact CD1-CE1 4.1Å; L356-Y435 HydrophobicContact CD1-CG 4.23Å; L356-Y435 HydrophobicContact CD2-CE1 4.09Å; L356-Y435 HydrophobicContact CG-CD1 4.31Å; L356-Y435 HydrophobicContact CG-CE1 4.39Å; L356-Y435 HydrophobicContact CG-CG 4.48Å; L357-Y435 HydrophobicContact CD2-CD2 4.12Å; Q360-Y435 HydrophobicContact CB-CE2 4.45Å; D366-Y435 HydrophobicContact CB-CE2 4.31Å; D366-Y435 WeakPolarHBondContact CB-OH 3.1Å; D366-Y435 PolarHBondContact OD2-OH 3.18Å; I370-Y435 HydrophobicContact CD1-CE1 3.87Å; I370-Y435 HydrophobicContact CG1-CE1 3.9Å; A432-Y435 PolarHBondContact O-N 3.04Å; Y435-G439 WeakPolarHBondContact O-CA 3.39Å; Y435-G439 PolarHBondContact O-N 3.45Å
436	V	88	Confident	87.1	Confident	3 Å²	3	20.2 Å²	20.2	2%	0.018	10%	0.102	C	C	.	.	H	α-helix	trans	-75.3	-35.2	-177.4	176.4	0	0	0	0	112.7	L63 I67 I428 Y429 A432 P433 Q434 T477	L63-V436 HydrophobicContact CD1-CG1 4.24Å; I67-V436 HydrophobicContact CD1-CB 4.45Å; I67-V436 HydrophobicContact CD1-CG1 4.47Å; I67-V436 HydrophobicContact CD1-CG2 4.22Å; I428-V436 HydrophobicContact CG2-CG2 3.78Å; Y429-V436 HydrophobicContact CD2-CB 4.3Å; Y429-V436 HydrophobicContact CD2-CG1 4.31Å; A432-V436 VanDerWaalsContact O-CG2 3.31Å; A432-V436 WeakPolarHBondContact O-CG2 3.42Å; A432-V436 PolarHBondContact O-N 3.35Å; P433-V436 PolarHBondContact O-N 3.36Å; Q434-V436 VanDerWaalsContact C-N 3.35Å; Q434-V436 PolarHBondContact O-N 3.39Å; V436-T477 WeakPolarHBondContact O-CG2 3.29Å; V436-T477 PolarHBondContact O-OG1 3.25Å
437	M	86.3	Confident	86	Confident	14 Å²	14	21.8 Å²	21.8	7%	0.069	12%	0.115	C	C	.	.	H	α-helix	trans	-74	-51.3	179.2	-78.1	178.3	72.9	0	0	112.4	Y429 P433 V476 T477 Y480	Y429-M437 HydrophobicContact CD2-CG 4.17Å; Y429-M437 HydrophobicContact CE2-CG 3.62Å; Y429-M437 HydrophobicContact CE2-SD 3.6Å; P433-M437 WeakPolarHBondContact O-CB 3.31Å; P433-M437 WeakPolarHBondContact O-CG 3.32Å; P433-M437 PolarHBondContact O-N 3.15Å; M437-V476 WeakPolarHBondContact O-CA 3.13Å; M437-T477 PolarHBondContact O-N 3.41Å; M437-T477 VanDerWaalsContact O-N 3.08Å; M437-Y480 HydrophobicContact CE-CD1 4.28Å; M437-Y480 HydrophobicContact CE-CE1 3.68Å; M437-Y480 HydrophobicContact CE-CE2 4.03Å; M437-Y480 HydrophobicContact CG-CD1 4.33Å; M437-Y480 HydrophobicContact CG-CD2 3.6Å; M437-Y480 HydrophobicContact CG-CE1 4.49Å; M437-Y480 HydrophobicContact CG-CE2 3.81Å; M437-Y480 HydrophobicContact CG-CG 3.87Å; M437-Y480 HydrophobicContact SD-CD2 4.13Å; M437-Y480 HydrophobicContact SD-CE1 4.4Å; M437-Y480 HydrophobicContact SD-CE2 3.67Å
438	Y	85.9	Confident	84.6	Confident	15 Å²	15	27.2 Å²	27.2	6%	0.059	15%	0.151	C	C	.	.	H	α-helix	trans	-119.9	-11.3	-168.2	-59.9	-69.1	0	0	0	113.6	Q434 S440 Q441 C465 C474 V476	Q434-Y438 PolarHBondContact O-N 3.43Å; Y438-S440 PolarHBondContact O-N 3.08Å; Y438-Q441 WeakPolarHBondContact O-CB 3.39Å; Y438-Q441 VanDerWaalsContact O-CG 3.29Å; Y438-Q441 WeakPolarHBondContact O-CG 3.4Å; Y438-Q441 PolarHBondContact O-N 3.24Å; Y438-Q441 PolarHBondContact O-NE2 3.42Å; Y438-C465 HydrophobicContact CD1-CB 3.88Å; Y438-C465 HydrophobicContact CD2-CB 4.44Å; Y438-C465 VanDerWaalsContact CD2-O 3.25Å; Y438-C465 WeakPolarHBondContact CD2-O 3.06Å; Y438-C465 HydrophobicContact CG-CB 3.83Å; Y438-C474 HydrophobicContact CD1-CB 4.25Å; Y438-C474 HydrophobicContact CE1-CB 4.18Å; Y438-V476 HydrophobicContact CD1-CG2 4.27Å; Y438-V476 HydrophobicContact CE1-CG2 3.55Å
439	G	87	Confident	82.9	Confident	0 Å²	0	28.5 Å²	28.5	0%	0	16%	0.16	C	C	.	.	T	Hydrogen-bonded Turn	trans	56.4	-136.7	-171.2	0	0	0	0	0	111.5	S71 L357 Q434 Y435 Q441	S71-G439 WeakPolarHBondContact OG-CA 3.01Å; L357-G439 WeakPolarHBondContact CD2-O 3.01Å; Q434-G439 PolarHBondContact O-N 3.38Å; Y435-G439 WeakPolarHBondContact O-CA 3.39Å; Y435-G439 PolarHBondContact O-N 3.45Å; G439-Q441 VanDerWaalsContact C-N 3.3Å; G439-Q441 PolarHBondContact O-N 2.95Å
440	S	86.8	Confident	81.5	Confident	46 Å²	46	35 Å²	35	32%	0.322	20%	0.2	S	C	.	.	T	Hydrogen-bonded Turn	trans	-92.4	16	-178.2	62.3	0	0	0	0	113.1	S71 Q360 Y438	S71-S440 PolarHBondContact OG-N 2.92Å; Q360-S440 VanDerWaalsContact OE1-CB 3.27Å; Y438-S440 PolarHBondContact O-N 3.08Å
441	Q	88.2	Confident	79.9	Confident	1 Å²	1	40.3 Å²	40.3	1%	0.005	23%	0.229	C	C	.	.			trans	-63.6	143	-177.8	-72.9	175.7	84.8	0	0	112	K74 Y438 G439 C465 T475	K74-Q441 HydrophobicContact CD-CB 4.44Å; K74-Q441 HydrophobicContact CD-CG 4.38Å; Y438-Q441 WeakPolarHBondContact O-CB 3.39Å; Y438-Q441 VanDerWaalsContact O-CG 3.29Å; Y438-Q441 WeakPolarHBondContact O-CG 3.4Å; Y438-Q441 PolarHBondContact O-N 3.24Å; Y438-Q441 PolarHBondContact O-NE2 3.42Å; G439-Q441 VanDerWaalsContact C-N 3.3Å; G439-Q441 PolarHBondContact O-N 2.95Å; Q441-C465 HydrophobicContact CB-CB 4.12Å; Q441-C465 VanDerWaalsContact CB-SG 3.53Å; Q441-C465 PolarHBondContact O-N 3.43Å; Q441-T475 PolarHBondContact NE2-O 3Å; Q441-T475 VanDerWaalsContact OE1-N 3.16Å; Q441-T475 PolarHBondContact OE1-OG1 2.69Å
442	K	89.3	Confident	78.3	Confident	78 Å²	78	46.4 Å²	46.4	34%	0.339	27%	0.269	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.6	158	174	-61.8	-176.2	-175.8	-179	0	109.5	K74 G78 K463	K74-K442 WeakPolarHBondContact CD-O 3.47Å; K74-K442 PolarHBondContact NZ-O 2.88Å; G78-K442 WeakPolarHBondContact CA-O 3.21Å; K442-K463 CarbonylContact C-O 3.55Å; K442-K463 WeakPolarHBondContact CA-O 2.96Å; K442-K463 VanDerWaalsContact CB-O 3.24Å; K442-K463 WeakPolarHBondContact CB-O 3.37Å
443	Y	89	Confident	77	Confident	14 Å²	14	53.1 Å²	53.1	6%	0.055	31%	0.309	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.1	166.1	174.7	74	-86.8	0	0	0	110.8	A445 T462 K463 I464 D466 A469 E473	Y443-A445 HydrophobicContact CD2-CB 4.48Å; Y443-A445 HydrophobicContact CE2-CB 3.94Å; Y443-T462 WeakPolarHBondContact O-CA 3.42Å; Y443-K463 HydrophobicContact CD1-CB 4.34Å; Y443-K463 HydrophobicContact CE1-CB 3.91Å; Y443-K463 HydrophobicContact CE2-CB 4.46Å; Y443-K463 PolarHBondContact N-O 3.17Å; Y443-K463 PolarHBondContact O-N 2.73Å; Y443-I464 VanDerWaalsContact CE1-O 3.28Å; Y443-I464 WeakPolarHBondContact CE1-O 3.29Å; Y443-D466 WeakPolarHBondContact CE1-OD1 3.5Å; Y443-D466 PolarHBondContact OH-OD1 2.91Å; Y443-D466 VanDerWaalsContact OH-OD1 3.04Å; Y443-A469 HydrophobicContact CD1-CB 3.87Å; Y443-A469 HydrophobicContact CD2-CB 4.46Å; Y443-A469 HydrophobicContact CE1-CB 3.61Å; Y443-A469 HydrophobicContact CE2-CB 4.27Å; Y443-A469 HydrophobicContact CG-CB 4.27Å; Y443-E473 WeakPolarHBondContact CB-OE2 3.38Å; Y443-E473 VanDerWaalsContact CD2-OE2 3.29Å; Y443-E473 WeakPolarHBondContact CD2-OE2 3.29Å
444	L	87	Confident	75.6	Confident	57 Å²	57	57.4 Å²	57.4	30%	0.298	33%	0.331	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-98	99.8	-176.7	-73.5	174.6	0	0	0	109.1	N77 T79 T462	N77-L444 VanDerWaalsContact O-CD2 3.26Å; N77-L444 WeakPolarHBondContact O-CD2 3.44Å; T79-L444 HydrophobicContact CG2-CD1 3.72Å; L444-T462 HydrophobicContact CD2-CG2 3.79Å
445	A	82.4	Confident	74.2	Confident	14 Å²	14	59.5 Å²	59.5	12%	0.116	36%	0.357	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-83	122.4	173.7	0	0	0	0	0	110	Y443 A447 T461 K463	Y443-A445 HydrophobicContact CD2-CB 4.48Å; Y443-A445 HydrophobicContact CE2-CB 3.94Å; A445-A447 PolarHBondContact O-N 3.01Å; A445-T461 PolarHBondContact N-O 3Å; A445-T461 PolarHBondContact O-N 3.4Å; A445-T461 PolarHBondContact O-OG1 3.17Å; A445-K463 HydrophobicContact CB-CB 4.37Å; A445-K463 HydrophobicContact CB-CD 3.61Å; A445-K463 HydrophobicContact CB-CG 3.83Å
446	Q	76.6	Confident	72.6	Confident	150 Å²	150	68.3 Å²	68.3	70%	0.701	40%	0.403	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-75.9	117.1	170.2	-66.3	179.9	-1.3	0	0	109.1
447	A	66.1	Low	71.3	Confident	34 Å²	34	71.1 Å²	71.1	28%	0.281	42%	0.421	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.4	142.2	173.2	0	0	0	0	0	110	A445 S449 V459	A445-A447 PolarHBondContact O-N 3.01Å; A447-S449 PolarHBondContact O-N 2.91Å; A447-V459 PolarHBondContact N-O 3.39Å; A447-V459 PolarHBondContact O-N 2.73Å
448	P	60.9	Low	70.2	Confident	116 Å²	116	75 Å²	75	75%	0.753	45%	0.445	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-63.1	134.3	171.5	25.3	-30.7	0	0	0	109.7	T450	P448-T450 PolarHBondContact O-N 3.46Å
449	S	55.8	Low	69.4	Low	29 Å²	29	77.5 Å²	77.5	20%	0.203	46%	0.462	C	S	.	.			trans	-60.9	128.1	177.4	51	0	0	0	0	111.3	A447 D451 G455 T457	A447-S449 PolarHBondContact O-N 2.91Å; S449-D451 VanDerWaalsContact C-N 3.3Å; S449-G455 PolarHBondContact OG-O 3.41Å; S449-T457 VanDerWaalsContact CB-O 3.25Å; S449-T457 WeakPolarHBondContact CB-O 3.45Å; S449-T457 PolarHBondContact N-O 3.29Å; S449-T457 PolarHBondContact OG-O 3.2Å; S449-T457 VanDerWaalsContact OG-O 3.06Å
450	T	56.7	Low	68.7	Low	142 Å²	142	80.8 Å²	80.8	87%	0.871	49%	0.485	S	S	*	.			trans	-84.9	-2.2	170.7	39.4	0	0	0	0	113.3	P448 P452	P448-T450 PolarHBondContact O-N 3.46Å; T450-P452 WeakPolarHBondContact O-CD 3.48Å
451	D	54.8	Low	68.4	Low	112 Å²	112	81.2 Å²	81.2	60%	0.599	49%	0.486	S	S	*	.			trans	-81	120.9	179.2	-83.3	-28	0	0	0	111.4	S449 V453	S449-D451 VanDerWaalsContact C-N 3.3Å; D451-V453 PolarHBondContact O-N 2.9Å
452	P	57.6	Low	68.2	Low	131 Å²	131	84.9 Å²	84.9	85%	0.851	51%	0.508	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.6	-3.3	-179.1	26.3	-30.5	0	0	0	114.4	T450	T450-P452 WeakPolarHBondContact O-CD 3.48Å
453	V	60.4	Low	68	Low	141 Å²	141	86.1 Å²	86.1	86%	0.855	51%	0.514	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.2	-24.1	-177.2	-178.4	0	0	0	0	112.3	D451	D451-V453 PolarHBondContact O-N 2.9Å
454	L	56.1	Low	67.8	Low	95 Å²	95	89.7 Å²	89.7	50%	0.497	53%	0.533	S	S	.	.	S	Bend	trans	-105.6	119	174.8	-152.2	73.5	0	0	0	104.6	T457	L454-T457 HydrophobicContact CD2-CG2 4.18Å; L454-T457 WeakPolarHBondContact CG-OG1 3.46Å
455	G	55.1	Low	67.7	Low	58 Å²	58	87 Å²	87	60%	0.598	52%	0.519	S	S	*	.			trans	-58.1	-162.5	-179	0	0	0	0	0	113.5	S449 T457	S449-G455 PolarHBondContact OG-O 3.41Å; G455-T457 PolarHBondContact O-N 2.95Å; G455-T457 PolarHBondContact O-OG1 3.08Å
456	N	55.5	Low	67.7	Low	184 Å²	184	88.2 Å²	88.2	98%	0.984	52%	0.524	S	S	*	.	S	Bend	trans	-54.1	81.6	175.4	-83.3	-5	0	0	0	112.5
457	T	59	Low	67.5	Low	63 Å²	63	81.9 Å²	81.9	39%	0.387	50%	0.497	S	S	.	.			trans	-124.2	115.5	-173.6	-29.5	0	0	0	0	105.9	S449 L454 G455 V459	S449-T457 VanDerWaalsContact CB-O 3.25Å; S449-T457 WeakPolarHBondContact CB-O 3.45Å; S449-T457 PolarHBondContact N-O 3.29Å; S449-T457 PolarHBondContact OG-O 3.2Å; S449-T457 VanDerWaalsContact OG-O 3.06Å; L454-T457 HydrophobicContact CD2-CG2 4.18Å; L454-T457 WeakPolarHBondContact CG-OG1 3.46Å; G455-T457 PolarHBondContact O-N 2.95Å; G455-T457 PolarHBondContact O-OG1 3.08Å; T457-V459 PolarHBondContact O-N 3.43Å
458	T	63.2	Low	67.9	Low	95 Å²	95	84.7 Å²	84.7	58%	0.583	51%	0.507	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-71.4	113.8	179.9	48.8	0	0	0	0	109.2
459	V	69.1	Low	68.6	Low	68 Å²	68	79.6 Å²	79.6	41%	0.412	47%	0.474	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.6	125.6	174.7	179.7	0	0	0	0	107.9	A447 T457 T461	A447-V459 PolarHBondContact N-O 3.39Å; A447-V459 PolarHBondContact O-N 2.73Å; T457-V459 PolarHBondContact O-N 3.43Å; V459-T461 HydrophobicContact CG1-CG2 4.3Å; V459-T461 PolarHBondContact O-N 3.24Å
460	S	73.1	Confident	69.7	Low	69 Å²	69	81.1 Å²	81.1	48%	0.483	48%	0.484	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-81.5	112.9	174.6	-61.8	0	0	0	0	108.9
461	T	81.6	Confident	70.3	Confident	54 Å²	54	80 Å²	80	33%	0.331	47%	0.468	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.4	139.8	177.1	56.9	0	0	0	0	109.9	A445 V459	A445-T461 PolarHBondContact N-O 3Å; A445-T461 PolarHBondContact O-N 3.4Å; A445-T461 PolarHBondContact O-OG1 3.17Å; V459-T461 HydrophobicContact CG1-CG2 4.3Å; V459-T461 PolarHBondContact O-N 3.24Å
462	T	83.5	Confident	71.4	Confident	78 Å²	78	79.3 Å²	79.3	48%	0.479	47%	0.465	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.6	121.6	177.6	48.4	0	0	0	0	109.9	N77 Y443 L444	N77-T462 WeakPolarHBondContact O-CG2 3.33Å; Y443-T462 WeakPolarHBondContact O-CA 3.42Å; L444-T462 HydrophobicContact CD2-CG2 3.79Å
463	K	84.9	Confident	72.5	Confident	104 Å²	104	76.1 Å²	76.1	45%	0.452	44%	0.439	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.4	151.2	173.9	-70.7	-167.2	-178.1	-179.5	0	110.7	K442 Y443 A445	K442-K463 CarbonylContact C-O 3.55Å; K442-K463 WeakPolarHBondContact CA-O 2.96Å; K442-K463 VanDerWaalsContact CB-O 3.24Å; K442-K463 WeakPolarHBondContact CB-O 3.37Å; Y443-K463 HydrophobicContact CD1-CB 4.34Å; Y443-K463 HydrophobicContact CE1-CB 3.91Å; Y443-K463 HydrophobicContact CE2-CB 4.46Å; Y443-K463 PolarHBondContact N-O 3.17Å; Y443-K463 PolarHBondContact O-N 2.73Å; A445-K463 HydrophobicContact CB-CB 4.37Å; A445-K463 HydrophobicContact CB-CD 3.61Å; A445-K463 HydrophobicContact CB-CG 3.83Å
464	I	85.3	Confident	73.7	Confident	89 Å²	89	70.5 Å²	70.5	46%	0.456	41%	0.406	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.9	140	173.9	-56.8	175	0	0	0	107.7	Q434 Y443 D466	Q434-I464 VanDerWaalsContact NE2-CG2 3.32Å; Y443-I464 VanDerWaalsContact CE1-O 3.28Å; Y443-I464 WeakPolarHBondContact CE1-O 3.29Å; I464-D466 PolarHBondContact O-N 2.91Å
465	C	85.2	Confident	75	Confident	0 Å²	0	66.3 Å²	66.3	0%	0	38%	0.384	C	S	.	.			trans	-57.6	118.8	177.7	-80.7	0	0	0	0	111.9	Q434 Y438 Q441 C474	Q434-C465 PolarHBondContact NE2-O 2.67Å; Y438-C465 HydrophobicContact CD1-CB 3.88Å; Y438-C465 HydrophobicContact CD2-CB 4.44Å; Y438-C465 VanDerWaalsContact CD2-O 3.25Å; Y438-C465 WeakPolarHBondContact CD2-O 3.06Å; Y438-C465 HydrophobicContact CG-CB 3.83Å; Q441-C465 HydrophobicContact CB-CB 4.12Å; Q441-C465 VanDerWaalsContact CB-SG 3.53Å; Q441-C465 PolarHBondContact O-N 3.43Å; C465-C474 WeakPolarHBondContact CA-SG 3.41Å; C465-C474 HydrophobicContact CB-CB 3.69Å; C465-C474 WeakPolarHBondContact CB-SG 3.15Å; C465-C474 WeakPolarHBondContact SG-CB 3.43Å; C465-C474 CovalentContact SG-SG 2.03Å; C465-C474 PolarHBondContact SG-SG 3.42Å
466	D	81.6	Confident	76.5	Confident	41 Å²	41	64.1 Å²	64.1	22%	0.219	36%	0.359	C	S	.	.			trans	-124.8	176.5	173.2	51.2	12.5	0	0	0	109	Y443 I464 D468 A469	Y443-D466 WeakPolarHBondContact CE1-OD1 3.5Å; Y443-D466 PolarHBondContact OH-OD1 2.91Å; Y443-D466 VanDerWaalsContact OH-OD1 3.04Å; I464-D466 PolarHBondContact O-N 2.91Å; D466-D468 PolarHBondContact O-N 2.76Å; D466-D468 PolarHBondContact OD1-N 3.44Å; D466-A469 VanDerWaalsContact O-CB 3.22Å; D466-A469 WeakPolarHBondContact O-CB 3.31Å; D466-A469 PolarHBondContact O-N 3.37Å; D466-A469 PolarHBondContact OD1-N 2.94Å
467	A	72.9	Confident	78	Confident	17 Å²	17	55.3 Å²	55.3	14%	0.14	31%	0.312	C	S	.	.	T	Hydrogen-bonded Turn	trans	-69	-13.1	175.7	0	0	0	0	0	113.2	K176 F344 A469	K176-A467 PolarHBondContact NZ-O 3.5Å; K176-A467 VanDerWaalsContact NZ-O 3.08Å; F344-A467 HydrophobicContact CB-CB 3.65Å; F344-A467 HydrophobicContact CD1-CB 3.9Å; F344-A467 HydrophobicContact CG-CB 4.23Å; F344-A467 WeakPolarHBondContact O-CB 3.48Å; F344-A467 PolarHBondContact O-N 3.04Å; A467-A469 VanDerWaalsContact C-N 3.28Å
468	D	73.4	Confident	79.3	Confident	93 Å²	93	54.3 Å²	54.3	50%	0.497	30%	0.301	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.1	-17.5	174.6	-69.8	-28.7	0	0	0	112.4	Q173 K176 D466	Q173-D468 PolarHBondContact NE2-OD1 3.41Å; K176-D468 PolarHBondContact NZ-O 3.34Å; D466-D468 PolarHBondContact O-N 2.76Å; D466-D468 PolarHBondContact OD1-N 3.44Å
469	A	76.5	Confident	80.3	Confident	8 Å²	8	49.9 Å²	49.9	7%	0.066	27%	0.274	C	S	.	.	S	Bend	trans	-52.4	143.2	174.4	0	0	0	0	0	112.2	K176 Y443 D466 A467 C474	K176-A469 PolarHBondContact NZ-O 3.49Å; Y443-A469 HydrophobicContact CD1-CB 3.87Å; Y443-A469 HydrophobicContact CD2-CB 4.46Å; Y443-A469 HydrophobicContact CE1-CB 3.61Å; Y443-A469 HydrophobicContact CE2-CB 4.27Å; Y443-A469 HydrophobicContact CG-CB 4.27Å; D466-A469 VanDerWaalsContact O-CB 3.22Å; D466-A469 WeakPolarHBondContact O-CB 3.31Å; D466-A469 PolarHBondContact O-N 3.37Å; D466-A469 PolarHBondContact OD1-N 2.94Å; A467-A469 VanDerWaalsContact C-N 3.28Å; A469-C474 HydrophobicContact CB-CB 4.14Å; A469-C474 WeakPolarHBondContact CB-SG 3.27Å
470	P	78.2	Confident	81	Confident	61 Å²	61	47.3 Å²	47.3	40%	0.396	26%	0.257	S	S	.	.	P	Polyproline II helix	trans	-66.2	157.4	176	27.4	-33.3	0	0	0	111.6	E473	P470-E473 HydrophobicContact CG-CB 3.98Å; P470-E473 HydrophobicContact CG-CG 3.74Å; P470-E473 PolarHBondContact O-N 3.45Å
471	E	70.4	Confident	81.2	Confident	118 Å²	118	44.2 Å²	44.2	55%	0.551	24%	0.235	S	C	*	.	T	Hydrogen-bonded Turn	trans	-57.2	145.4	177.7	-65.5	173.6	-169.5	0	0	110.4	E473	E471-E473 PolarHBondContact O-N 3.01Å
472	D	75.9	Confident	81.1	Confident	98 Å²	98	41.9 Å²	41.9	52%	0.524	22%	0.22	S	C	.	.	T	Hydrogen-bonded Turn	trans	66.4	-10.2	-175.1	-61.6	-38.9	0	0	0	117.9	Y80 R90	Y80-D472 PolarHBondContact OH-O 3.31Å; R90-D472 PolarHBondContact NH1-O 3.28Å
473	E	81.8	Confident	81	Confident	65 Å²	65	38.4 Å²	38.4	30%	0.304	20%	0.198	S	C	.	.	T	Hydrogen-bonded Turn	trans	-82.7	-30.6	177.1	-72.9	-162	-169.4	0	0	113.3	K74 Y80 Y443 P470 E471	K74-E473 WeakPolarHBondContact CE-O 3.33Å; K74-E473 PolarHBondContact NZ-O 3.2Å; Y80-E473 PolarHBondContact OH-O 3.48Å; Y443-E473 WeakPolarHBondContact CB-OE2 3.38Å; Y443-E473 VanDerWaalsContact CD2-OE2 3.29Å; Y443-E473 WeakPolarHBondContact CD2-OE2 3.29Å; P470-E473 HydrophobicContact CG-CB 3.98Å; P470-E473 HydrophobicContact CG-CG 3.74Å; P470-E473 PolarHBondContact O-N 3.45Å; E471-E473 PolarHBondContact O-N 3.01Å
474	C	85.6	Confident	80.6	Confident	23 Å²	23	33.6 Å²	33.6	16%	0.155	18%	0.178	C	C	.	.			trans	-124.3	132.1	179.2	-66.3	0	0	0	0	110.9	Y438 C465 A469	Y438-C474 HydrophobicContact CD1-CB 4.25Å; Y438-C474 HydrophobicContact CE1-CB 4.18Å; C465-C474 WeakPolarHBondContact CA-SG 3.41Å; C465-C474 HydrophobicContact CB-CB 3.69Å; C465-C474 WeakPolarHBondContact CB-SG 3.15Å; C465-C474 WeakPolarHBondContact SG-CB 3.43Å; C465-C474 CovalentContact SG-SG 2.03Å; C465-C474 PolarHBondContact SG-SG 3.42Å; A469-C474 HydrophobicContact CB-CB 4.14Å; A469-C474 WeakPolarHBondContact CB-SG 3.27Å
475	T	84.3	Confident	80.4	Confident	7 Å²	7	30 Å²	30	4%	0.043	16%	0.159	C	C	.	.	P	Polyproline II helix	trans	-101.3	135.1	178.1	54.9	0	0	0	0	109.9	V70 Q441	V70-T475 WeakPolarHBondContact CG1-O 3.44Å; V70-T475 WeakPolarHBondContact CG1-OG1 3.38Å; Q441-T475 PolarHBondContact NE2-O 3Å; Q441-T475 VanDerWaalsContact OE1-N 3.16Å; Q441-T475 PolarHBondContact OE1-OG1 2.69Å
476	V	84.9	Confident	80.3	Confident	11 Å²	11	30.1 Å²	30.1	7%	0.067	16%	0.159	C	C	.	.	P	Polyproline II helix	trans	-98.4	144.3	179.3	-173.9	0	0	0	0	109.6	L180 M437 Y438 Y480 L481	L180-V476 HydrophobicContact CD1-CG2 4.37Å; M437-V476 WeakPolarHBondContact O-CA 3.13Å; Y438-V476 HydrophobicContact CD1-CG2 4.27Å; Y438-V476 HydrophobicContact CE1-CG2 3.55Å; V476-Y480 HydrophobicContact CG1-CD1 3.42Å; V476-Y480 VanDerWaalsContact CG1-CD1 3.42Å; V476-Y480 HydrophobicContact CG1-CE1 4.14Å; V476-Y480 HydrophobicContact CG1-CG 4.05Å; V476-L481 HydrophobicContact CG1-CG 4.39Å
477	T	87.9	Confident	80.3	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	17%	0.166	C	C	.	.	P	Polyproline II helix	trans	-59.4	144.9	175.2	55.3	0	0	0	0	113	D66 I67 V70 V436 M437 T479 Y480 L481	D66-T477 WeakPolarHBondContact OD2-CB 3.39Å; I67-T477 HydrophobicContact CB-CG2 4.48Å; I67-T477 HydrophobicContact CG1-CG2 3.95Å; V70-T477 HydrophobicContact CB-CG2 4.38Å; V70-T477 HydrophobicContact CG2-CG2 4.22Å; V436-T477 WeakPolarHBondContact O-CG2 3.29Å; V436-T477 PolarHBondContact O-OG1 3.25Å; M437-T477 PolarHBondContact O-N 3.41Å; M437-T477 VanDerWaalsContact O-N 3.08Å; T477-T479 VanDerWaalsContact C-N 3.31Å; T477-T479 PolarHBondContact O-N 3.42Å; T477-Y480 PolarHBondContact O-N 3.32Å; T477-Y480 WeakPolarHBondContact OG1-CB 3.38Å; T477-L481 PolarHBondContact O-N 3.43Å
478	R	86.7	Confident	80.9	Confident	41 Å²	41	34.7 Å²	34.7	16%	0.155	17%	0.172	C	C	.	.	H	α-helix	trans	-70.3	-31.5	-177.7	-61.2	-54.7	179	-178.8	1.9	112.1	D66 E94 V97 L481 F482	D66-R478 PolarHBondContact OD1-N 2.91Å; D66-R478 PolarHBondContact OD2-N 3.38Å; E94-R478 VanDerWaalsContact CD-NH2 3.26Å; E94-R478 IonicContact OE2-CZ 3.49Å; E94-R478 IonicContact OE2-NH2 3.04Å; E94-R478 PolarHBondContact OE2-NH2 2.96Å; V97-R478 HydrophobicContact CG1-CB 4.38Å; V97-R478 HydrophobicContact CG1-CG 4.45Å; R478-L481 PolarHBondContact O-N 3.39Å; R478-F482 WeakPolarHBondContact O-CB 3.43Å; R478-F482 PolarHBondContact O-N 3.44Å
479	T	84.1	Confident	81.6	Confident	3 Å²	3	30.8 Å²	30.8	2%	0.018	15%	0.15	C	C	.	.	H	α-helix	trans	-61.1	-44.1	175.1	-49.8	0	0	0	0	112.6	L63 D66 Y101 T477 F482 L483	L63-T479 HydrophobicContact CD1-CG2 3.89Å; D66-T479 PolarHBondContact OD2-N 2.81Å; D66-T479 PolarHBondContact OD2-OG1 3.26Å; Y101-T479 HydrophobicContact CE1-CG2 4.42Å; Y101-T479 VanDerWaalsContact CE2-OG1 3.24Å; Y101-T479 WeakPolarHBondContact CE2-OG1 3.38Å; Y101-T479 PolarHBondContact OH-OG1 2.99Å; T477-T479 VanDerWaalsContact C-N 3.31Å; T477-T479 PolarHBondContact O-N 3.42Å; T479-F482 PolarHBondContact O-N 2.81Å; T479-L483 HydrophobicContact CG2-CD1 3.82Å; T479-L483 HydrophobicContact CG2-CG 4.36Å; T479-L483 PolarHBondContact O-N 3.4Å
480	Y	82.3	Confident	82.1	Confident	13 Å²	13	30.4 Å²	30.4	5%	0.051	15%	0.147	C	C	.	.	H	α-helix	trans	-59.8	-50.4	180	169.6	-96.3	0	0	0	110.6	I342 Y429 M437 V476 T477 F482 L483 H484	I342-Y480 WeakPolarHBondContact CG2-OH 3.49Å; Y429-Y480 AromaticContact CD2-CD2 3.86Å; Y429-Y480 HydrophobicContact CD2-CD2 3.86Å; Y429-Y480 HydrophobicContact CD2-CE2 4.19Å; Y429-Y480 HydrophobicContact CE1-CE2 4.27Å; Y429-Y480 AromaticContact CE2-CD2 3.66Å; Y429-Y480 HydrophobicContact CE2-CD2 3.66Å; Y429-Y480 AromaticContact CE2-CE2 3.53Å; Y429-Y480 HydrophobicContact CE2-CE2 3.53Å; Y429-Y480 HydrophobicContact CG-CD2 4.49Å; Y429-Y480 AromaticContact CZ-CE2 3.55Å; M437-Y480 HydrophobicContact CE-CD1 4.28Å; M437-Y480 HydrophobicContact CE-CE1 3.68Å; M437-Y480 HydrophobicContact CE-CE2 4.03Å; M437-Y480 HydrophobicContact CG-CD1 4.33Å; M437-Y480 HydrophobicContact CG-CD2 3.6Å; M437-Y480 HydrophobicContact CG-CE1 4.49Å; M437-Y480 HydrophobicContact CG-CE2 3.81Å; M437-Y480 HydrophobicContact CG-CG 3.87Å; M437-Y480 HydrophobicContact SD-CD2 4.13Å; M437-Y480 HydrophobicContact SD-CE1 4.4Å; M437-Y480 HydrophobicContact SD-CE2 3.67Å; V476-Y480 HydrophobicContact CG1-CD1 3.42Å; V476-Y480 VanDerWaalsContact CG1-CD1 3.42Å; V476-Y480 HydrophobicContact CG1-CE1 4.14Å; V476-Y480 HydrophobicContact CG1-CG 4.05Å; T477-Y480 PolarHBondContact O-N 3.32Å; T477-Y480 WeakPolarHBondContact OG1-CB 3.38Å; Y480-F482 PolarHBondContact O-N 3.11Å; Y480-L483 PolarHBondContact O-N 3.49Å; Y480-H484 AromaticContact CD2-CD2 3.49Å; Y480-H484 VanDerWaalsContact CD2-CD2 3.49Å; Y480-H484 WeakPolarHBondContact CD2-CD2 3.22Å; Y480-H484 HydrophobicContact CE2-CB 4.18Å; Y480-H484 AromaticContact CE2-CD2 3.64Å; Y480-H484 AromaticContact CE2-CG 3.84Å; Y480-H484 WeakPolarHBondContact O-CB 3.39Å; Y480-H484 PolarHBondContact O-CD2 3.43Å; Y480-H484 PolarHBondContact O-N 3.49Å
481	L	78.5	Confident	82.5	Confident	4 Å²	4	28.2 Å²	28.2	2%	0.021	13%	0.133	C	C	.	.	H	α-helix	trans	-60	-36.7	178.9	-64.6	167.4	0	0	0	111.9	L180 F181 L184 V476 T477 R478 K485	L180-L481 HydrophobicContact CB-CD2 4.12Å; F181-L481 HydrophobicContact CD1-CD2 4.46Å; F181-L481 HydrophobicContact CE1-CD2 4.24Å; L184-L481 HydrophobicContact CD1-CD1 3.82Å; L184-L481 HydrophobicContact CD2-CB 3.81Å; L184-L481 HydrophobicContact CD2-CD1 3.91Å; L184-L481 HydrophobicContact CD2-CG 4.45Å; V476-L481 HydrophobicContact CG1-CG 4.39Å; T477-L481 PolarHBondContact O-N 3.43Å; R478-L481 PolarHBondContact O-N 3.39Å; L481-K485 PolarHBondContact O-N 3.37Å
482	F	80.1	Confident	83.6	Confident	6 Å²	6	26 Å²	26	3%	0.026	12%	0.124	C	C	.	.	H	α-helix	trans	-70	-43.4	-179.3	-165.6	-87.7	0	0	0	113	Y105 L190 L193 S194 I197 R478 T479 Y480	Y105-F482 AromaticContact CD2-CD1 3.8Å; Y105-F482 HydrophobicContact CD2-CD1 3.8Å; Y105-F482 AromaticContact CD2-CE1 3.39Å; Y105-F482 HydrophobicContact CD2-CE1 3.39Å; Y105-F482 HydrophobicContact CD2-CE2 4.31Å; Y105-F482 HydrophobicContact CD2-CG 4.41Å; Y105-F482 AromaticContact CD2-CZ 3.71Å; Y105-F482 HydrophobicContact CD2-CZ 3.71Å; Y105-F482 AromaticContact CE2-CD1 3.41Å; Y105-F482 HydrophobicContact CE2-CD1 3.41Å; Y105-F482 VanDerWaalsContact CE2-CD1 3.41Å; Y105-F482 AromaticContact CE2-CE1 3.5Å; Y105-F482 HydrophobicContact CE2-CE1 3.5Å; Y105-F482 HydrophobicContact CE2-CG 4.02Å; Y105-F482 HydrophobicContact CE2-CZ 4.21Å; Y105-F482 HydrophobicContact CG-CE1 4.26Å; L190-F482 HydrophobicContact CD1-CD2 3.98Å; L190-F482 HydrophobicContact CD1-CE2 3.74Å; L193-F482 HydrophobicContact CB-CE2 4.45Å; L193-F482 HydrophobicContact CB-CZ 4.09Å; L193-F482 HydrophobicContact CD2-CE1 4.34Å; L193-F482 HydrophobicContact CD2-CE2 3.67Å; L193-F482 HydrophobicContact CD2-CZ 3.27Å; L193-F482 HydrophobicContact CG-CZ 3.96Å; S194-F482 PolarHBondContact OG-O 3.34Å; I197-F482 HydrophobicContact CB-CE1 3.84Å; I197-F482 HydrophobicContact CG1-CE1 4Å; I197-F482 HydrophobicContact CG1-CZ 4.35Å; I197-F482 HydrophobicContact CG2-CE1 3.94Å; R478-F482 WeakPolarHBondContact O-CB 3.43Å; R478-F482 PolarHBondContact O-N 3.44Å; T479-F482 PolarHBondContact O-N 2.81Å; Y480-F482 PolarHBondContact O-N 3.11Å
483	L	79.9	Confident	84.4	Confident	4 Å²	4	21.3 Å²	21.3	2%	0.021	10%	0.099	C	C	.	.	H	α-helix	trans	-83	-28.6	-175.8	-67	176.1	0	0	0	113.3	I197 T201 Y426 T479 Y480	I197-L483 HydrophobicContact CG2-CD2 4.19Å; T201-L483 HydrophobicContact CG2-CD2 4.33Å; Y426-L483 HydrophobicContact CD2-CB 4.47Å; T479-L483 HydrophobicContact CG2-CD1 3.82Å; T479-L483 HydrophobicContact CG2-CG 4.36Å; T479-L483 PolarHBondContact O-N 3.4Å; Y480-L483 PolarHBondContact O-N 3.49Å
484	H	78.1	Confident	84.8	Confident	4 Å²	4	19 Å²	19	2%	0.019	9%	0.087	C	C	.	.	H	α-helix	trans	-101.3	6.6	-176.2	-70.8	-86.9	0	0	0	114.6	F181 Y426 Y429 Y480 F486 S490	F181-H484 WeakPolarHBondContact CZ-O 3.46Å; Y426-H484 AromaticContact CD2-CE1 3.96Å; Y426-H484 AromaticContact CD2-NE2 3.76Å; Y426-H484 AromaticContact CE2-CE1 3.1Å; Y426-H484 WeakPolarHBondContact CE2-CE1 3.48Å; Y426-H484 AromaticContact CE2-ND1 3.89Å; Y426-H484 AromaticContact CE2-NE2 3.37Å; Y426-H484 WeakPolarHBondContact CE2-NE2 3.07Å; Y426-H484 AromaticContact CZ-CE1 3.73Å; Y429-H484 AromaticContact CD1-CE1 3.37Å; Y429-H484 WeakPolarHBondContact CD1-CE1 2.96Å; Y429-H484 AromaticContact CD1-NE2 3.11Å; Y429-H484 WeakPolarHBondContact CD1-NE2 3.14Å; Y429-H484 AromaticContact CE1-CE1 3.3Å; Y429-H484 WeakPolarHBondContact CE1-CE1 3.5Å; Y429-H484 AromaticContact CE1-NE2 3.43Å; Y429-H484 WeakPolarHBondContact CE1-NE2 3.4Å; Y429-H484 AromaticContact CG-NE2 3.64Å; Y480-H484 AromaticContact CD2-CD2 3.49Å; Y480-H484 VanDerWaalsContact CD2-CD2 3.49Å; Y480-H484 WeakPolarHBondContact CD2-CD2 3.22Å; Y480-H484 HydrophobicContact CE2-CB 4.18Å; Y480-H484 AromaticContact CE2-CD2 3.64Å; Y480-H484 AromaticContact CE2-CG 3.84Å; Y480-H484 WeakPolarHBondContact O-CB 3.39Å; Y480-H484 PolarHBondContact O-CD2 3.43Å; Y480-H484 PolarHBondContact O-N 3.49Å; H484-F486 PolarHBondContact O-N 3.3Å; H484-F486 VanDerWaalsContact O-N 3.08Å; H484-S490 PolarHBondContact ND1-OG 3.04Å
485	K	80.4	Confident	85.2	Confident	14 Å²	14	23.1 Å²	23.1	6%	0.061	10%	0.103	C	C	.	.	S	Bend	trans	-52	-33.9	179.8	-175	161.6	179.8	143.4	0	114.2	L163 F181 L481	L163-K485 HydrophobicContact CD1-CG 4.44Å; L163-K485 HydrophobicContact CD2-CG 4.33Å; F181-K485 HydrophobicContact CD1-CB 4.34Å; F181-K485 HydrophobicContact CD1-CG 4.29Å; F181-K485 VanDerWaalsContact CE1-CA 3.45Å; F181-K485 HydrophobicContact CE1-CB 4.26Å; L481-K485 PolarHBondContact O-N 3.37Å
486	F	82.8	Confident	85.7	Confident	1 Å²	1	23 Å²	23	0%	0.004	10%	0.103	C	C	.	.	S	Bend	trans	-108.8	116	-178.5	-63.1	-77.8	0	0	0	110.1	V161 L163 F195 H484 F488 F489 S490	V161-F486 HydrophobicContact CB-CE1 4.16Å; V161-F486 HydrophobicContact CG1-CD1 4.04Å; V161-F486 HydrophobicContact CG1-CE1 3.69Å; L163-F486 HydrophobicContact CD2-CD1 3.52Å; L163-F486 HydrophobicContact CD2-CE1 3.53Å; L163-F486 HydrophobicContact CD2-CG 4.42Å; L163-F486 HydrophobicContact CD2-CZ 4.42Å; L163-F486 HydrophobicContact CG-CE1 4.43Å; F195-F486 HydrophobicContact CB-CD2 4.48Å; F195-F486 HydrophobicContact CB-CE2 3.64Å; F195-F486 HydrophobicContact CB-CZ 3.73Å; F195-F486 HydrophobicContact CD2-CD1 4.48Å; F195-F486 HydrophobicContact CD2-CD2 4.48Å; F195-F486 HydrophobicContact CD2-CE1 4.17Å; F195-F486 HydrophobicContact CD2-CE2 4.2Å; F195-F486 HydrophobicContact CD2-CZ 4.04Å; F195-F486 HydrophobicContact CG-CE2 4.44Å; F195-F486 HydrophobicContact CG-CZ 4.38Å; H484-F486 PolarHBondContact O-N 3.3Å; H484-F486 VanDerWaalsContact O-N 3.08Å; F486-F488 VanDerWaalsContact C-N 3.33Å; F486-F488 HydrophobicContact CB-CD1 4.21Å; F486-F488 HydrophobicContact CB-CE1 3.67Å; F486-F488 HydrophobicContact CB-CE2 4.43Å; F486-F488 HydrophobicContact CB-CZ 3.77Å; F486-F488 AromaticContact CD1-CE1 3.72Å; F486-F488 HydrophobicContact CD1-CE1 3.72Å; F486-F488 AromaticContact CD1-CZ 3.92Å; F486-F488 HydrophobicContact CD1-CZ 3.92Å; F486-F488 HydrophobicContact CG-CE1 4.03Å; F486-F488 AromaticContact CG-CZ 3.98Å; F486-F488 HydrophobicContact CG-CZ 3.98Å; F486-F488 PolarHBondContact O-N 2.69Å; F486-F489 HydrophobicContact CB-CD2 3.69Å; F486-F489 HydrophobicContact CB-CE2 4.45Å; F486-F489 HydrophobicContact CD2-CD2 4.25Å; F486-F489 HydrophobicContact CD2-CE2 4.46Å; F486-F489 HydrophobicContact CG-CD2 4.18Å; F486-F489 PolarHBondContact O-N 2.94Å; F486-S490 PolarHBondContact O-N 3.28Å
487	W	81.3	Confident	86.2	Confident	94 Å²	94	22.6 Å²	22.6	36%	0.356	10%	0.1	S	C	.	.	H	α-helix	trans	-60.9	-38.3	-176	69.7	-91.2	0	0	0	113	I337 S338 G340 F489 S490 T491	I337-W487 WeakPolarHBondContact O-CZ3 3.49Å; S338-W487 WeakPolarHBondContact O-CZ3 3.41Å; G340-W487 VanDerWaalsContact CA-O 3.26Å; G340-W487 WeakPolarHBondContact CA-O 3.41Å; W487-F489 PolarHBondContact O-N 2.72Å; W487-S490 WeakPolarHBondContact O-CB 3.08Å; W487-S490 PolarHBondContact O-N 3.2Å; W487-S490 VanDerWaalsContact O-N 3.16Å; W487-T491 PolarHBondContact O-N 3.4Å; W487-T491 PolarHBondContact O-OG1 2.82Å
488	F	85.2	Confident	86.5	Confident	61 Å²	61	26.8 Å²	26.8	27%	0.268	12%	0.116	S	C	.	.	H	α-helix	trans	-67.1	-35.4	-176.9	59.8	-94.4	0	0	0	113	V161 F195 F486 S490 T491 I492	V161-F488 HydrophobicContact CG1-CE1 4.45Å; F195-F488 HydrophobicContact CD2-CZ 4.26Å; F195-F488 HydrophobicContact CE2-CE2 4.33Å; F195-F488 AromaticContact CE2-CZ 3.86Å; F195-F488 HydrophobicContact CE2-CZ 3.86Å; F486-F488 VanDerWaalsContact C-N 3.33Å; F486-F488 HydrophobicContact CB-CD1 4.21Å; F486-F488 HydrophobicContact CB-CE1 3.67Å; F486-F488 HydrophobicContact CB-CE2 4.43Å; F486-F488 HydrophobicContact CB-CZ 3.77Å; F486-F488 AromaticContact CD1-CE1 3.72Å; F486-F488 HydrophobicContact CD1-CE1 3.72Å; F486-F488 AromaticContact CD1-CZ 3.92Å; F486-F488 HydrophobicContact CD1-CZ 3.92Å; F486-F488 HydrophobicContact CG-CE1 4.03Å; F486-F488 AromaticContact CG-CZ 3.98Å; F486-F488 HydrophobicContact CG-CZ 3.98Å; F486-F488 PolarHBondContact O-N 2.69Å; F488-S490 VanDerWaalsContact C-N 3.34Å; F488-T491 WeakPolarHBondContact O-CB 3.44Å; F488-T491 PolarHBondContact O-N 3.3Å; F488-I492 WeakPolarHBondContact O-CG1 3.37Å; F488-I492 PolarHBondContact O-N 3.47Å; F488-I492 VanDerWaalsContact O-N 3.12Å
489	F	89.1	Confident	87	Confident	10 Å²	10	27.1 Å²	27.1	4%	0.044	13%	0.128	C	C	.	.	H	α-helix	trans	-63.7	-43	173.1	-79.7	-58.8	0	0	0	110.4	F195 S199 L202 F486 W487 T491 I492 Y493	F195-F489 AromaticContact CD2-CE2 3.77Å; F195-F489 HydrophobicContact CD2-CE2 3.77Å; F195-F489 HydrophobicContact CD2-CZ 4.35Å; F195-F489 AromaticContact CE2-CE2 3.8Å; F195-F489 HydrophobicContact CE2-CE2 3.8Å; F195-F489 HydrophobicContact CE2-CZ 4.03Å; F195-F489 HydrophobicContact CG-CE2 4.46Å; F195-F489 HydrophobicContact CZ-CE2 4.5Å; F195-F489 HydrophobicContact CZ-CZ 4.31Å; S199-F489 WeakPolarHBondContact OG-CZ 3.5Å; L202-F489 HydrophobicContact CD2-CE1 4.38Å; F486-F489 HydrophobicContact CB-CD2 3.69Å; F486-F489 HydrophobicContact CB-CE2 4.45Å; F486-F489 HydrophobicContact CD2-CD2 4.25Å; F486-F489 HydrophobicContact CD2-CE2 4.46Å; F486-F489 HydrophobicContact CG-CD2 4.18Å; F486-F489 PolarHBondContact O-N 2.94Å; W487-F489 PolarHBondContact O-N 2.72Å; F489-T491 VanDerWaalsContact C-N 3.32Å; F489-T491 PolarHBondContact O-N 3.26Å; F489-I492 PolarHBondContact O-N 2.93Å; F489-I492 VanDerWaalsContact O-N 3.11Å; F489-Y493 HydrophobicContact CB-CD2 4.48Å; F489-Y493 HydrophobicContact CB-CE2 3.74Å; F489-Y493 WeakPolarHBondContact O-CD2 3.33Å; F489-Y493 WeakPolarHBondContact O-CE2 3.16Å; F489-Y493 PolarHBondContact O-N 3.46Å
490	S	85.8	Confident	87.6	Confident	1 Å²	1	27.1 Å²	27.1	1%	0.007	13%	0.128	C	C	.	.	H	α-helix	trans	-58.4	-41.3	175.7	-61.1	0	0	0	0	112.4	G340 H484 F486 W487 F488 I492 Y493 Y494	G340-S490 VanDerWaalsContact O-CB 3.29Å; G340-S490 WeakPolarHBondContact O-CB 3.47Å; H484-S490 PolarHBondContact ND1-OG 3.04Å; F486-S490 PolarHBondContact O-N 3.28Å; W487-S490 WeakPolarHBondContact O-CB 3.08Å; W487-S490 PolarHBondContact O-N 3.2Å; W487-S490 VanDerWaalsContact O-N 3.16Å; F488-S490 VanDerWaalsContact C-N 3.34Å; S490-I492 PolarHBondContact O-N 2.85Å; S490-Y493 PolarHBondContact O-N 3.4Å; S490-Y494 PolarHBondContact O-N 3.04Å
491	T	88.3	Confident	88.3	Confident	15 Å²	15	27.1 Å²	27.1	9%	0.092	13%	0.129	C	C	.	.	H	α-helix	trans	-59	-46.6	173	-61.7	0	0	0	0	111.9	I337 G340 F341 W487 F488 F489 Y493 Y494 F495	I337-T491 HydrophobicContact CG2-CG2 4.07Å; I337-T491 PolarHBondContact O-OG1 3.5Å; I337-T491 VanDerWaalsContact O-OG1 3.11Å; G340-T491 VanDerWaalsContact CA-OG1 3.26Å; G340-T491 WeakPolarHBondContact CA-OG1 3.38Å; F341-T491 HydrophobicContact CD2-CG2 4.38Å; F341-T491 HydrophobicContact CE2-CG2 4.21Å; W487-T491 PolarHBondContact O-N 3.4Å; W487-T491 PolarHBondContact O-OG1 2.82Å; F488-T491 WeakPolarHBondContact O-CB 3.44Å; F488-T491 PolarHBondContact O-N 3.3Å; F489-T491 VanDerWaalsContact C-N 3.32Å; F489-T491 PolarHBondContact O-N 3.26Å; T491-Y493 PolarHBondContact O-N 3.01Å; T491-Y494 WeakPolarHBondContact O-CB 3.5Å; T491-Y494 PolarHBondContact O-N 3.45Å; T491-F495 HydrophobicContact CG2-CD2 4.17Å; T491-F495 HydrophobicContact CG2-CE2 3.8Å; T491-F495 VanDerWaalsContact O-CD2 3.24Å; T491-F495 WeakPolarHBondContact O-CD2 3.42Å; T491-F495 PolarHBondContact O-N 3.19Å
492	I	92.4	Very high	89.1	Confident	70 Å²	70	28.4 Å²	28.4	36%	0.359	14%	0.142	S	C	.	.	H	α-helix	trans	-64.3	-43.6	-179.3	-63.1	164.5	0	0	0	110.7	L202 M205 F488 F489 S490 Y494 F495 G496	L202-I492 HydrophobicContact CD1-CB 4.23Å; L202-I492 HydrophobicContact CD1-CD1 4.44Å; L202-I492 HydrophobicContact CD1-CG2 3.36Å; M205-I492 HydrophobicContact CE-CG2 3.89Å; M205-I492 HydrophobicContact SD-CG2 4.44Å; F488-I492 WeakPolarHBondContact O-CG1 3.37Å; F488-I492 PolarHBondContact O-N 3.47Å; F488-I492 VanDerWaalsContact O-N 3.12Å; F489-I492 PolarHBondContact O-N 2.93Å; F489-I492 VanDerWaalsContact O-N 3.11Å; S490-I492 PolarHBondContact O-N 2.85Å; I492-Y494 VanDerWaalsContact C-N 3.3Å; I492-Y494 PolarHBondContact O-N 3.3Å; I492-F495 PolarHBondContact O-N 3.45Å; I492-G496 PolarHBondContact O-N 2.03Å
493	Y	91.9	Very high	89.9	Confident	1 Å²	1	29.4 Å²	29.4	0%	0.004	15%	0.152	C	C	.	.	H	α-helix	trans	-65	-33.5	178.6	-55.9	-43.4	0	0	0	113	S198 T201 L202 M205 Y426 F489 S490 T491 G496 N497	S198-Y493 PolarHBondContact O-OH 2.95Å; T201-Y493 PolarHBondContact OG1-OH 3.01Å; L202-Y493 HydrophobicContact CB-CE1 4.32Å; L202-Y493 HydrophobicContact CD1-CE1 4.27Å; M205-Y493 HydrophobicContact SD-CD1 3.81Å; Y426-Y493 HydrophobicContact CD1-CD2 4.16Å; Y426-Y493 HydrophobicContact CD1-CG 4.11Å; Y426-Y493 AromaticContact CD2-CD2 3.71Å; Y426-Y493 HydrophobicContact CD2-CD2 3.71Å; Y426-Y493 AromaticContact CD2-CE2 3.92Å; Y426-Y493 HydrophobicContact CD2-CE2 3.92Å; Y426-Y493 HydrophobicContact CD2-CG 4.45Å; Y426-Y493 AromaticContact CE1-CD2 3.77Å; Y426-Y493 HydrophobicContact CE1-CD2 3.77Å; Y426-Y493 AromaticContact CE1-CG 3.67Å; Y426-Y493 HydrophobicContact CE1-CG 3.67Å; Y426-Y493 AromaticContact CE2-CD2 3.16Å; Y426-Y493 HydrophobicContact CE2-CD2 3.16Å; Y426-Y493 AromaticContact CE2-CE2 3.75Å; Y426-Y493 HydrophobicContact CE2-CE2 3.75Å; Y426-Y493 AromaticContact CE2-CG 3.97Å; Y426-Y493 HydrophobicContact CE2-CG 3.97Å; Y426-Y493 HydrophobicContact CG-CD2 4.17Å; Y426-Y493 HydrophobicContact CG-CE2 4.47Å; Y426-Y493 AromaticContact CZ-CD2 3.24Å; Y426-Y493 AromaticContact CZ-CG 3.6Å; Y426-Y493 VanDerWaalsContact OH-CB 3.26Å; Y426-Y493 WeakPolarHBondContact OH-CB 3.3Å; F489-Y493 HydrophobicContact CB-CD2 4.48Å; F489-Y493 HydrophobicContact CB-CE2 3.74Å; F489-Y493 WeakPolarHBondContact O-CD2 3.33Å; F489-Y493 WeakPolarHBondContact O-CE2 3.16Å; F489-Y493 PolarHBondContact O-N 3.46Å; S490-Y493 PolarHBondContact O-N 3.4Å; T491-Y493 PolarHBondContact O-N 3.01Å; Y493-G496 CarbonylContact O-C 3.37Å; Y493-G496 WeakPolarHBondContact O-CA 3.28Å; Y493-G496 PolarHBondContact O-N 3.45Å; Y493-G496 VanDerWaalsContact O-N 3.16Å; Y493-N497 PolarHBondContact O-N 3.34Å
494	Y	91.5	Very high	90.7	Very high	16 Å²	16	29.3 Å²	29.3	6%	0.063	15%	0.151	C	C	.	.	H	α-helix	trans	-57.7	-48.7	173.3	166.8	-98.1	0	0	0	111.5	N327 K330 F341 S490 T491 I492 G496 N497 W498	N327-Y494 HydrophobicContact CB-CE2 3.99Å; K330-Y494 HydrophobicContact CB-CD2 4.09Å; K330-Y494 HydrophobicContact CB-CE2 3.82Å; K330-Y494 HydrophobicContact CD-CD2 3.97Å; K330-Y494 HydrophobicContact CD-CE2 4.5Å; F341-Y494 HydrophobicContact CB-CD2 4.25Å; F341-Y494 HydrophobicContact CB-CG 4.19Å; F341-Y494 HydrophobicContact CD1-CD1 4.34Å; F341-Y494 HydrophobicContact CD1-CD2 4.5Å; F341-Y494 HydrophobicContact CD1-CE1 4.22Å; F341-Y494 HydrophobicContact CD1-CE2 4.38Å; F341-Y494 HydrophobicContact CD1-CG 4.48Å; F341-Y494 AromaticContact CD2-CD1 3.63Å; F341-Y494 HydrophobicContact CD2-CD1 3.63Å; F341-Y494 HydrophobicContact CD2-CE1 4.2Å; F341-Y494 AromaticContact CD2-CG 3.84Å; F341-Y494 HydrophobicContact CD2-CG 3.84Å; F341-Y494 HydrophobicContact CE1-CD1 4.34Å; F341-Y494 AromaticContact CE1-CE1 3.93Å; F341-Y494 HydrophobicContact CE1-CE1 3.93Å; F341-Y494 AromaticContact CE2-CD1 3.59Å; F341-Y494 HydrophobicContact CE2-CD1 3.59Å; F341-Y494 AromaticContact CE2-CE1 3.88Å; F341-Y494 HydrophobicContact CE2-CE1 3.88Å; F341-Y494 HydrophobicContact CE2-CG 4.28Å; F341-Y494 HydrophobicContact CG-CD1 4.01Å; F341-Y494 HydrophobicContact CG-CD2 4.22Å; F341-Y494 HydrophobicContact CG-CE1 4.35Å; F341-Y494 AromaticContact CG-CG 3.94Å; F341-Y494 HydrophobicContact CG-CG 3.94Å; F341-Y494 AromaticContact CZ-CD1 3.96Å; F341-Y494 HydrophobicContact CZ-CD1 3.96Å; F341-Y494 AromaticContact CZ-CE1 3.74Å; F341-Y494 HydrophobicContact CZ-CE1 3.74Å; S490-Y494 PolarHBondContact O-N 3.04Å; T491-Y494 WeakPolarHBondContact O-CB 3.5Å; T491-Y494 PolarHBondContact O-N 3.45Å; I492-Y494 VanDerWaalsContact C-N 3.3Å; I492-Y494 PolarHBondContact O-N 3.3Å; Y494-G496 VanDerWaalsContact C-N 3.3Å; Y494-G496 PolarHBondContact O-N 3.04Å; Y494-N497 PolarHBondContact O-N 3.05Å; Y494-W498 AromaticContact CE1-NE1 3.93Å; Y494-W498 AromaticContact CE2-NE1 3.69Å; Y494-W498 AromaticContact CZ-CD1 3.84Å; Y494-W498 AromaticContact CZ-NE1 3.31Å; Y494-W498 VanDerWaalsContact CZ-NE1 3.31Å; Y494-W498 PolarHBondContact OH-NE1 3.04Å; Y494-W498 VanDerWaalsContact OH-NE1 3.07Å
495	F	93.6	Very high	91.5	Very high	109 Å²	109	33.7 Å²	33.7	48%	0.478	17%	0.174	S	C	.	.	H	α-helix	trans	-66.2	-34.5	174	-69.4	-68.1	0	0	0	112.2	F341 T491 I492 N497 W498 A499	F341-F495 HydrophobicContact CE2-CE2 4.29Å; F341-F495 HydrophobicContact CE2-CZ 4.37Å; T491-F495 HydrophobicContact CG2-CD2 4.17Å; T491-F495 HydrophobicContact CG2-CE2 3.8Å; T491-F495 VanDerWaalsContact O-CD2 3.24Å; T491-F495 WeakPolarHBondContact O-CD2 3.42Å; T491-F495 PolarHBondContact O-N 3.19Å; I492-F495 PolarHBondContact O-N 3.45Å; F495-N497 VanDerWaalsContact C-N 3.3Å; F495-N497 PolarHBondContact O-N 3.45Å; F495-W498 WeakPolarHBondContact O-CB 3.14Å; F495-W498 PolarHBondContact O-N 3.42Å; F495-A499 PolarHBondContact O-N 3.25Å
496	G	94.8	Very high	92.2	Very high	5 Å²	5	38.5 Å²	38.5	5%	0.052	20%	0.199	C	C	.	.	H	α-helix	trans	-56.6	-40.1	172.2	0	0	0	0	0	113.5	I492 Y493 Y494 W498 A499 F500	I492-G496 PolarHBondContact O-N 2.03Å; Y493-G496 CarbonylContact O-C 3.37Å; Y493-G496 WeakPolarHBondContact O-CA 3.28Å; Y493-G496 PolarHBondContact O-N 3.45Å; Y493-G496 VanDerWaalsContact O-N 3.16Å; Y494-G496 VanDerWaalsContact C-N 3.3Å; Y494-G496 PolarHBondContact O-N 3.04Å; G496-W498 PolarHBondContact O-N 3.09Å; G496-A499 WeakPolarHBondContact O-CB 2.9Å; G496-A499 PolarHBondContact O-N 3.2Å; G496-F500 WeakPolarHBondContact O-CB 3.42Å; G496-F500 PolarHBondContact O-N 2.67Å
497	N	94.5	Very high	92.7	Very high	2 Å²	2	38.7 Å²	38.7	1%	0.011	20%	0.202	C	C	.	.	H	α-helix	trans	-63.6	-40.1	176.5	-68	-24.7	0	0	0	112.1	N327 S430 Y493 Y494 F495 F500 I501	N327-N497 WeakPolarHBondContact ND2-CB 3.1Å; N327-N497 PolarHBondContact OD1-ND2 3.2Å; N327-N497 VanDerWaalsContact OD1-ND2 3.12Å; S430-N497 WeakPolarHBondContact CB-ND2 3.22Å; S430-N497 PolarHBondContact OG-ND2 3.3Å; S430-N497 VanDerWaalsContact OG-ND2 3.13Å; Y493-N497 PolarHBondContact O-N 3.34Å; Y494-N497 PolarHBondContact O-N 3.05Å; F495-N497 VanDerWaalsContact C-N 3.3Å; F495-N497 PolarHBondContact O-N 3.45Å; N497-F500 WeakPolarHBondContact O-CB 3.42Å; N497-F500 PolarHBondContact O-N 2.73Å; N497-I501 WeakPolarHBondContact O-CG1 3.39Å; N497-I501 PolarHBondContact O-N 3Å
498	W	95.4	Very high	93.2	Very high	88 Å²	88	36.6 Å²	36.6	33%	0.333	20%	0.197	S	C	.	.	H	α-helix	trans	-63.8	-43.2	173.9	-77.6	108.4	0	0	0	111.8	F324 N327 Y494 F495 G496 F500 I501 G502	F324-W498 AromaticContact CD2-CH2 3.79Å; F324-W498 HydrophobicContact CD2-CH2 3.79Å; F324-W498 AromaticContact CD2-CZ3 3.7Å; F324-W498 HydrophobicContact CD2-CZ3 3.7Å; F324-W498 AromaticContact CE2-CH2 3.57Å; F324-W498 HydrophobicContact CE2-CH2 3.57Å; F324-W498 AromaticContact CE2-CZ3 3.63Å; F324-W498 HydrophobicContact CE2-CZ3 3.63Å; F324-W498 HydrophobicContact CZ-CH2 4.45Å; N327-W498 HydrophobicContact CB-CZ2 4.05Å; Y494-W498 AromaticContact CE1-NE1 3.93Å; Y494-W498 AromaticContact CE2-NE1 3.69Å; Y494-W498 AromaticContact CZ-CD1 3.84Å; Y494-W498 AromaticContact CZ-NE1 3.31Å; Y494-W498 VanDerWaalsContact CZ-NE1 3.31Å; Y494-W498 PolarHBondContact OH-NE1 3.04Å; Y494-W498 VanDerWaalsContact OH-NE1 3.07Å; F495-W498 WeakPolarHBondContact O-CB 3.14Å; F495-W498 PolarHBondContact O-N 3.42Å; G496-W498 PolarHBondContact O-N 3.09Å; W498-F500 VanDerWaalsContact C-N 3.31Å; W498-F500 PolarHBondContact O-N 3.06Å; W498-I501 HydrophobicContact CE3-CD1 4.49Å; W498-I501 PolarHBondContact O-N 3.02Å; W498-G502 PolarHBondContact O-N 3.44Å
499	A	97.1	Very high	93.6	Very high	48 Å²	48	38 Å²	38	40%	0.397	21%	0.21	S	C	.	.	H	α-helix	trans	-61.9	-39.4	174.9	0	0	0	0	0	111.9	I209 F495 G496 G502 A503	I209-A499 HydrophobicContact CD1-CB 3.97Å; F495-A499 PolarHBondContact O-N 3.25Å; G496-A499 WeakPolarHBondContact O-CB 2.9Å; G496-A499 PolarHBondContact O-N 3.2Å; A499-G502 PolarHBondContact O-N 3.35Å; A499-A503 WeakPolarHBondContact O-CB 3.2Å; A499-A503 PolarHBondContact O-N 2.93Å
500	F	96.9	Very high	93.7	Very high	4 Å²	4	41 Å²	41	2%	0.018	23%	0.23	C	C	.	.	H	α-helix	trans	-60.9	-46.6	175.1	178.7	-94	0	0	0	112.1	V208 I209 T212 A213 M216 L323 F377 M427 G496 N497 W498 G502 A503 F504	V208-F500 HydrophobicContact CG1-CD2 3.7Å; V208-F500 HydrophobicContact CG1-CE2 3.55Å; I209-F500 HydrophobicContact CG1-CB 4.11Å; T212-F500 HydrophobicContact CG2-CE2 4.36Å; A213-F500 HydrophobicContact CB-CD2 3.8Å; A213-F500 HydrophobicContact CB-CE2 3.75Å; A213-F500 HydrophobicContact CB-CG 4.48Å; A213-F500 HydrophobicContact CB-CZ 4.39Å; M216-F500 HydrophobicContact CE-CE1 3.58Å; M216-F500 HydrophobicContact CE-CE2 4.42Å; M216-F500 HydrophobicContact CE-CZ 3.35Å; M216-F500 HydrophobicContact SD-CE1 4.4Å; M216-F500 HydrophobicContact SD-CZ 3.81Å; L323-F500 HydrophobicContact CD1-CD1 3.88Å; L323-F500 HydrophobicContact CD1-CE1 3.93Å; F377-F500 HydrophobicContact CE1-CZ 4.45Å; M427-F500 HydrophobicContact SD-CZ 4.35Å; G496-F500 WeakPolarHBondContact O-CB 3.42Å; G496-F500 PolarHBondContact O-N 2.67Å; N497-F500 WeakPolarHBondContact O-CB 3.42Å; N497-F500 PolarHBondContact O-N 2.73Å; W498-F500 VanDerWaalsContact C-N 3.31Å; W498-F500 PolarHBondContact O-N 3.06Å; F500-G502 PolarHBondContact O-N 2.99Å; F500-A503 PolarHBondContact O-N 3.49Å; F500-F504 WeakPolarHBondContact O-CB 3.38Å; F500-F504 PolarHBondContact O-N 2.85Å
501	I	96.4	Very high	93.8	Very high	13 Å²	13	41.2 Å²	41.2	7%	0.067	23%	0.231	C	C	.	.	H	α-helix	trans	-59.7	-47.3	175.8	-66.8	166	0	0	0	110.2	T320 L323 F324 N497 W498 A503 F504 L505	T320-I501 HydrophobicContact CG2-CG1 4.41Å; T320-I501 HydrophobicContact CG2-CG2 4.07Å; L323-I501 HydrophobicContact CB-CD1 4.22Å; F324-I501 HydrophobicContact CB-CD1 4.22Å; N497-I501 WeakPolarHBondContact O-CG1 3.39Å; N497-I501 PolarHBondContact O-N 3Å; W498-I501 HydrophobicContact CE3-CD1 4.49Å; W498-I501 PolarHBondContact O-N 3.02Å; I501-A503 PolarHBondContact O-N 3.46Å; I501-F504 PolarHBondContact O-N 3.3Å; I501-L505 HydrophobicContact CG2-CD1 4.31Å; I501-L505 WeakPolarHBondContact O-CG 3.48Å; I501-L505 PolarHBondContact O-N 2.83Å
502	G	96.6	Very high	93.9	Very high	30 Å²	30	43.6 Å²	43.6	31%	0.309	25%	0.248	S	C	.	.	H	α-helix	trans	-60	-46.6	177.6	0	0	0	0	0	112.9	W498 A499 F500 F504 L505 I506	W498-G502 PolarHBondContact O-N 3.44Å; A499-G502 PolarHBondContact O-N 3.35Å; F500-G502 PolarHBondContact O-N 2.99Å; G502-F504 VanDerWaalsContact C-N 3.33Å; G502-F504 PolarHBondContact O-N 3.48Å; G502-L505 PolarHBondContact O-N 2.94Å; G502-I506 WeakPolarHBondContact O-CG1 3.1Å; G502-I506 PolarHBondContact O-N 3Å
503	A	96.1	Very high	93.7	Very high	28 Å²	28	45.4 Å²	45.4	23%	0.231	27%	0.265	C	S	.	.	H	α-helix	trans	-62.7	-38.2	177.5	0	0	0	0	0	112.3	I209 A213 A499 F500 I501 G507	I209-A503 HydrophobicContact CG2-CB 3.97Å; A213-A503 HydrophobicContact CB-CB 3.86Å; A499-A503 WeakPolarHBondContact O-CB 3.2Å; A499-A503 PolarHBondContact O-N 2.93Å; F500-A503 PolarHBondContact O-N 3.49Å; I501-A503 PolarHBondContact O-N 3.46Å; A503-G507 PolarHBondContact O-N 2.93Å
504	F	96.1	Very high	93.3	Very high	2 Å²	2	50.5 Å²	50.5	1%	0.009	28%	0.284	C	S	.	.	H	α-helix	trans	-63.5	-46.5	174.9	169.3	-105.7	0	0	0	111.8	A213 M216 A316 L317 T320 F500 I501 G502 G507 L508	A213-F504 HydrophobicContact CB-CB 4.24Å; M216-F504 HydrophobicContact CB-CD2 4Å; M216-F504 HydrophobicContact CB-CE2 4.01Å; M216-F504 HydrophobicContact CE-CB 4.28Å; M216-F504 HydrophobicContact CE-CD2 3.5Å; M216-F504 VanDerWaalsContact CE-CD2 3.5Å; M216-F504 HydrophobicContact CE-CE2 4Å; M216-F504 HydrophobicContact CE-CG 3.95Å; A316-F504 HydrophobicContact CB-CE2 3.89Å; A316-F504 HydrophobicContact CB-CZ 3.86Å; L317-F504 HydrophobicContact CD2-CE1 4.48Å; T320-F504 HydrophobicContact CG2-CD1 4Å; T320-F504 HydrophobicContact CG2-CE1 4.24Å; T320-F504 WeakPolarHBondContact OG1-CD1 3.29Å; T320-F504 VanDerWaalsContact OG1-CE1 3.32Å; T320-F504 WeakPolarHBondContact OG1-CE1 3.34Å; F500-F504 WeakPolarHBondContact O-CB 3.38Å; F500-F504 PolarHBondContact O-N 2.85Å; I501-F504 PolarHBondContact O-N 3.3Å; G502-F504 VanDerWaalsContact C-N 3.33Å; G502-F504 PolarHBondContact O-N 3.48Å; F504-G507 PolarHBondContact O-N 2.88Å; F504-L508 HydrophobicContact CE1-CD1 4.19Å; F504-L508 HydrophobicContact CE2-CD1 4.5Å; F504-L508 HydrophobicContact CZ-CD1 3.84Å; F504-L508 WeakPolarHBondContact O-CB 3.35Å; F504-L508 PolarHBondContact O-N 3.31Å
505	L	95.3	Very high	92.6	Very high	96 Å²	96	52.4 Å²	52.4	50%	0.503	31%	0.309	S	S	.	.	H	α-helix	trans	-62.2	-45.6	178.6	-68.6	176.1	0	0	0	111.8	I501 G502 G507 L508 V509	I501-L505 HydrophobicContact CG2-CD1 4.31Å; I501-L505 WeakPolarHBondContact O-CG 3.48Å; I501-L505 PolarHBondContact O-N 2.83Å; G502-L505 PolarHBondContact O-N 2.94Å; L505-G507 VanDerWaalsContact C-N 3.34Å; L505-G507 PolarHBondContact O-N 2.97Å; L505-L508 PolarHBondContact O-N 3.18Å; L505-V509 WeakPolarHBondContact O-CG2 3.24Å; L505-V509 PolarHBondContact O-N 2.81Å
506	I	95	Very high	91.9	Very high	114 Å²	114	53.5 Å²	53.5	59%	0.585	31%	0.314	S	S	*	.	H	α-helix	trans	-60	-47.2	174.4	-67.3	162.7	0	0	0	110.1	G502 L508 V509 V510	G502-I506 WeakPolarHBondContact O-CG1 3.1Å; G502-I506 PolarHBondContact O-N 3Å; I506-L508 VanDerWaalsContact C-N 3.27Å; I506-L508 PolarHBondContact O-N 3.1Å; I506-V509 PolarHBondContact O-N 3.07Å; I506-V510 HydrophobicContact CG2-CG2 4.25Å; I506-V510 WeakPolarHBondContact O-CG2 3.25Å; I506-V510 PolarHBondContact O-N 2.58Å
507	G	92.9	Very high	91	Very high	5 Å²	5	54.8 Å²	54.8	5%	0.052	32%	0.318	C	S	.	.	H	α-helix	trans	-59.5	-36.8	178	0	0	0	0	0	113	S217 A503 F504 L505 S511	S217-G507 PolarHBondContact OG-O 3.46Å; A503-G507 PolarHBondContact O-N 2.93Å; F504-G507 PolarHBondContact O-N 2.88Å; L505-G507 VanDerWaalsContact C-N 3.34Å; L505-G507 PolarHBondContact O-N 2.97Å; G507-S511 WeakPolarHBondContact O-CB 3.46Å; G507-S511 PolarHBondContact O-N 2.85Å; G507-S511 PolarHBondContact O-OG 3.14Å
508	L	92.9	Very high	89.7	Confident	50 Å²	50	56 Å²	56	26%	0.262	33%	0.327	S	S	.	.	H	α-helix	trans	-66.5	-47.1	175.8	-169.1	149.9	0	0	0	111.3	F504 L505 I506 S511 C512	F504-L508 HydrophobicContact CE1-CD1 4.19Å; F504-L508 HydrophobicContact CE2-CD1 4.5Å; F504-L508 HydrophobicContact CZ-CD1 3.84Å; F504-L508 WeakPolarHBondContact O-CB 3.35Å; F504-L508 PolarHBondContact O-N 3.31Å; L505-L508 PolarHBondContact O-N 3.18Å; I506-L508 VanDerWaalsContact C-N 3.27Å; I506-L508 PolarHBondContact O-N 3.1Å; L508-S511 PolarHBondContact O-N 3.15Å; L508-C512 WeakPolarHBondContact O-CB 3.28Å; L508-C512 PolarHBondContact O-N 3.34Å; L508-C512 PolarHBondContact O-SG 3.09Å
509	V	93.6	Very high	88.4	Confident	90 Å²	90	54 Å²	54	55%	0.545	32%	0.324	S	S	.	.	H	α-helix	trans	-60.3	-51	175.8	175	0	0	0	0	110.9	L505 I506 S511 C512 C513	L505-V509 WeakPolarHBondContact O-CG2 3.24Å; L505-V509 PolarHBondContact O-N 2.81Å; I506-V509 PolarHBondContact O-N 3.07Å; V509-S511 VanDerWaalsContact C-N 3.34Å; V509-S511 PolarHBondContact O-N 3.25Å; V509-C512 WeakPolarHBondContact O-CB 3.28Å; V509-C512 PolarHBondContact O-N 2.96Å; V509-C512 VanDerWaalsContact O-N 3.16Å; V509-C513 PolarHBondContact O-N 2.89Å; V509-C513 PolarHBondContact O-SG 3.44Å; V509-C513 VanDerWaalsContact O-SG 3.36Å
510	V	90.8	Very high	86.8	Confident	74 Å²	74	52 Å²	52	45%	0.448	31%	0.307	S	S	.	.	H	α-helix	trans	-59.7	-45.1	179.6	171.7	0	0	0	0	111.2	I506 C512 C513 R514	I506-V510 HydrophobicContact CG2-CG2 4.25Å; I506-V510 WeakPolarHBondContact O-CG2 3.25Å; I506-V510 PolarHBondContact O-N 2.58Å; V510-C512 VanDerWaalsContact C-N 3.31Å; V510-C512 PolarHBondContact O-N 3.16Å; V510-C513 PolarHBondContact O-N 3.13Å; V510-R514 WeakPolarHBondContact O-CB 3.4Å; V510-R514 PolarHBondContact O-N 3.47Å
511	S	88.8	Confident	85.2	Confident	5 Å²	5	56.2 Å²	56.2	4%	0.035	33%	0.326	C	S	.	.	H	α-helix	trans	-68.7	-29.9	179.6	-63.9	0	0	0	0	112.3	K225 G507 L508 V509	K225-S511 PolarHBondContact NZ-O 2.95Å; G507-S511 WeakPolarHBondContact O-CB 3.46Å; G507-S511 PolarHBondContact O-N 2.85Å; G507-S511 PolarHBondContact O-OG 3.14Å; L508-S511 PolarHBondContact O-N 3.15Å; V509-S511 VanDerWaalsContact C-N 3.34Å; V509-S511 PolarHBondContact O-N 3.25Å
512	C	88.5	Confident	83.3	Confident	66 Å²	66	56.6 Å²	56.6	45%	0.446	33%	0.334	S	S	.	.	H	α-helix	trans	-68.5	-40.1	171.6	-77.7	0	0	0	0	112.1	K225 L508 V509 V510	K225-C512 VanDerWaalsContact NZ-C 3.34Å; K225-C512 PolarHBondContact NZ-O 2.91Å; L508-C512 WeakPolarHBondContact O-CB 3.28Å; L508-C512 PolarHBondContact O-N 3.34Å; L508-C512 PolarHBondContact O-SG 3.09Å; V509-C512 WeakPolarHBondContact O-CB 3.28Å; V509-C512 PolarHBondContact O-N 2.96Å; V509-C512 VanDerWaalsContact O-N 3.16Å; V510-C512 VanDerWaalsContact C-N 3.31Å; V510-C512 PolarHBondContact O-N 3.16Å
513	C	88.5	Confident	81.7	Confident	107 Å²	107	59.7 Å²	59.7	72%	0.723	34%	0.34	S	S	*	.	H	α-helix	trans	-74.8	-26.9	178	-63.8	0	0	0	0	113.8	V509 V510	V509-C513 PolarHBondContact O-N 2.89Å; V509-C513 PolarHBondContact O-SG 3.44Å; V509-C513 VanDerWaalsContact O-SG 3.36Å; V510-C513 PolarHBondContact O-N 3.13Å
514	R	84.6	Confident	79.8	Confident	108 Å²	108	59.7 Å²	59.7	41%	0.408	34%	0.337	S	S	.	.	S	Bend	trans	-71	136	-175.8	-168.5	170.8	157.4	151.7	-2.2	112.6	K225 V510 E521	K225-R514 PolarHBondContact NZ-O 2.86Å; V510-R514 WeakPolarHBondContact O-CB 3.4Å; V510-R514 PolarHBondContact O-N 3.47Å; R514-E521 IonicContact NH2-OE1 3.58Å
515	G	75.3	Confident	78.1	Confident	57 Å²	57	62.3 Å²	62.3	59%	0.588	35%	0.35	S	S	*	.			trans	-66.6	175.6	-179.1	0	0	0	0	0	115
516	K	80	Confident	75.9	Confident	132 Å²	132	61.6 Å²	61.6	57%	0.574	36%	0.358	S	S	*	.	P	Polyproline II helix	trans	-64.1	142.5	174.3	-68.6	-179.8	-179	175.4	0	110.5	K225 R228	K225-K516 HydrophobicContact CB-CG 4.45Å; R228-K516 HydrophobicContact CG-CB 3.79Å
517	K	76.5	Confident	73.9	Confident	32 Å²	32	62.7 Å²	62.7	14%	0.139	36%	0.364	C	S	.	.	B	Isolated β-bridge	trans	-75.8	152.5	176.8	-72.4	-167	168.1	-123.1	0	111.9	T227 R228 N387 E521	T227-K517 CarbonylContact C-O 3.59Å; T227-K517 VanDerWaalsContact CA-O 3.29Å; T227-K517 WeakPolarHBondContact CA-O 3.32Å; R228-K517 PolarHBondContact N-O 3.12Å; N387-K517 PolarHBondContact OD1-NZ 3.37Å; K517-E521 WeakPolarHBondContact CA-OE2 3.26Å; K517-E521 WeakPolarHBondContact CB-OE2 3.47Å; K517-E521 WeakPolarHBondContact CG-OE2 3.48Å; K517-E521 IonicContact NZ-OE1 2.59Å; K517-E521 PolarHBondContact NZ-OE1 2.91Å
518	S	66.6	Low	72.1	Confident	27 Å²	27	63.4 Å²	63.4	19%	0.189	37%	0.367	C	S	.	.	P	Polyproline II helix	trans	-74.2	152.5	173.4	167.9	0	0	0	0	111.5	E233 I520 E521	E233-S518 VanDerWaalsContact CD-OG 3.23Å; E233-S518 WeakPolarHBondContact OE1-CA 3.39Å; E233-S518 WeakPolarHBondContact OE1-CB 3.34Å; E233-S518 PolarHBondContact OE1-OG 2.53Å; E233-S518 VanDerWaalsContact OE1-OG 3.09Å; E233-S518 PolarHBondContact OE2-OG 2.84Å; S518-I520 PolarHBondContact O-N 3.45Å; S518-I520 PolarHBondContact OG-N 2.9Å; S518-E521 PolarHBondContact N-OE2 3.42Å; S518-E521 WeakPolarHBondContact O-CB 3.38Å; S518-E521 PolarHBondContact O-N 3.03Å
519	V	68.3	Low	70	Confident	46 Å²	46	64.8 Å²	64.8	28%	0.279	38%	0.381	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.4	-27.8	178.9	-178	0	0	0	0	111.4	R228 V230 E233	R228-V519 WeakPolarHBondContact O-CG2 3.21Å; V230-V519 HydrophobicContact CG2-CB 4.2Å; V230-V519 HydrophobicContact CG2-CG1 3.84Å; V230-V519 HydrophobicContact CG2-CG2 3.84Å; E233-V519 PolarHBondContact OE2-N 3.43Å
520	I	63.5	Low	67.7	Low	6 Å²	6	68 Å²	68	3%	0.031	40%	0.395	C	S	.	.	T	Hydrogen-bonded Turn	trans	-102.5	11	-175.4	-58.4	176.5	0	0	0	110.9	R282 H285 L286 S518 G522 E523 V524	R282-I520 HydrophobicContact CG-CD1 4.49Å; H285-I520 HydrophobicContact CB-CD1 3.78Å; H285-I520 HydrophobicContact CB-CG2 4.12Å; L286-I520 HydrophobicContact CB-CD1 4.07Å; L286-I520 HydrophobicContact CD1-CD1 4.32Å; L286-I520 HydrophobicContact CD2-CD1 3.22Å; L286-I520 HydrophobicContact CD2-CG1 4.03Å; L286-I520 HydrophobicContact CG-CD1 3.22Å; L286-I520 HydrophobicContact CG-CG1 4.48Å; S518-I520 PolarHBondContact O-N 3.45Å; S518-I520 PolarHBondContact OG-N 2.9Å; I520-G522 PolarHBondContact O-N 3.01Å; I520-E523 HydrophobicContact CG2-CB 3.73Å; I520-E523 PolarHBondContact O-N 2.86Å; I520-V524 HydrophobicContact CG2-CB 4.02Å; I520-V524 HydrophobicContact CG2-CG2 3.74Å
521	E	62.8	Low	65.5	Low	92 Å²	92	68.6 Å²	68.6	43%	0.43	40%	0.395	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.8	106.7	-178.1	-167	172.4	147.5	0	0	111	R514 K517 S518	R514-E521 IonicContact NH2-OE1 3.58Å; K517-E521 WeakPolarHBondContact CA-OE2 3.26Å; K517-E521 WeakPolarHBondContact CB-OE2 3.47Å; K517-E521 WeakPolarHBondContact CG-OE2 3.48Å; K517-E521 IonicContact NZ-OE1 2.59Å; K517-E521 PolarHBondContact NZ-OE1 2.91Å; S518-E521 PolarHBondContact N-OE2 3.42Å; S518-E521 WeakPolarHBondContact O-CB 3.38Å; S518-E521 PolarHBondContact O-N 3.03Å
522	G	57.4	Low	63.3	Low	22 Å²	22	72.3 Å²	72.3	23%	0.227	42%	0.421	C	S	.	.	T	Hydrogen-bonded Turn	trans	104.6	-4.1	-177.8	0	0	0	0	0	116.3	I520	I520-G522 PolarHBondContact O-N 3.01Å
523	E	61.8	Low	61.3	Low	95 Å²	95	73.3 Å²	73.3	44%	0.444	42%	0.422	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.7	-35.1	174.9	-70.6	-172.3	-178.5	0	0	113.6	H285 R404 I520	H285-E523 IonicContact CE1-OE2 3.36Å; H285-E523 IonicContact ND1-OE2 3.95Å; H285-E523 PolarHBondContact ND1-OE2 3.16Å; R404-E523 PolarHBondContact NH1-O 2.76Å; I520-E523 HydrophobicContact CG2-CB 3.73Å; I520-E523 PolarHBondContact O-N 2.86Å
524	V	57.3	Low	59.2	Low	28 Å²	28	74.4 Å²	74.4	17%	0.17	42%	0.421	C	S	.	.			trans	-133.4	112.6	-179.6	-175.4	0	0	0	0	109.4	R281 R282 H285 I520	R281-V524 HydrophobicContact CB-CG1 4.31Å; R282-V524 HydrophobicContact CB-CG1 4.32Å; H285-V524 HydrophobicContact CB-CG2 4.06Å; H285-V524 VanDerWaalsContact CD2-CG2 3.4Å; H285-V524 WeakPolarHBondContact CD2-CG2 3.25Å; I520-V524 HydrophobicContact CG2-CB 4.02Å; I520-V524 HydrophobicContact CG2-CG2 3.74Å
525	E	59.3	Low	57.4	Low	57 Å²	57	73 Å²	73	27%	0.266	42%	0.419	S	S	.	.			trans	-129.4	156.2	170.4	-63.9	-167	150.1	0	0	112	K399 R401 D527 D528	K399-E525 IonicContact NZ-OE1 2.71Å; K399-E525 PolarHBondContact NZ-OE1 3.41Å; K399-E525 IonicContact NZ-OE2 3.48Å; K399-E525 PolarHBondContact NZ-OE2 3.47Å; R401-E525 IonicContact CZ-OE2 2.83Å; R401-E525 IonicContact NH2-OE2 2.72Å; R401-E525 PolarHBondContact NH2-OE2 2.9Å; E525-D527 PolarHBondContact O-N 2.84Å; E525-D527 VanDerWaalsContact O-N 3.09Å; E525-D528 PolarHBondContact N-OD2 3.47Å; E525-D528 VanDerWaalsContact N-OD2 3.09Å; E525-D528 WeakPolarHBondContact O-CB 3.43Å; E525-D528 PolarHBondContact O-N 3.1Å
526	A	50.5	Low	55.8	Low	81 Å²	81	76.1 Å²	76.1	67%	0.669	41%	0.414	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.9	-21.8	-178.2	0	0	0	0	0	114
527	D	52.4	Low	53.7	Low	136 Å²	136	75.3 Å²	75.3	73%	0.727	42%	0.42	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.3	-6.8	178.1	-117.5	6.7	0	0	0	113.4	E525 S529	E525-D527 PolarHBondContact O-N 2.84Å; E525-D527 VanDerWaalsContact O-N 3.09Å; D527-S529 PolarHBondContact O-N 3.36Å
528	D	55.3	Low	51.6	Low	21 Å²	21	86.2 Å²	86.2	11%	0.112	47%	0.471	C	S	.	.	G	3₁₀ helix	trans	-81.9	27.7	-179.2	-63.8	-27.9	0	0	0	112.4	R281 R401 E525 D530	R281-D528 PolarHBondContact NH1-O 3.23Å; R401-D528 IonicContact CZ-OD1 3.66Å; R401-D528 IonicContact NH1-OD1 3.8Å; R401-D528 PolarHBondContact NH1-OD1 2.99Å; R401-D528 IonicContact NH1-OD2 2.83Å; R401-D528 PolarHBondContact NH1-OD2 3.43Å; R401-D528 IonicContact NH2-OD1 2.65Å; R401-D528 PolarHBondContact NH2-OD1 3.26Å; E525-D528 PolarHBondContact N-OD2 3.47Å; E525-D528 VanDerWaalsContact N-OD2 3.09Å; E525-D528 WeakPolarHBondContact O-CB 3.43Å; E525-D528 PolarHBondContact O-N 3.1Å; D528-D530 PolarHBondContact O-N 3.39Å
529	S	48	Very low	50.9	Low	79 Å²	79	89.2 Å²	89.2	55%	0.552	49%	0.485	S	S	*	.	G	3₁₀ helix	trans	-70.4	-16.4	-177.2	48.4	0	0	0	0	114	D527	D527-S529 PolarHBondContact O-N 3.36Å
530	D	45.9	Very low	49.9	Very low	156 Å²	156	91.4 Å²	91.4	83%	0.834	50%	0.495	S	S	*	.	G	3₁₀ helix	trans	-104.8	0.4	-174.1	-70.4	-21.4	0	0	0	115.7	D528	D528-D530 PolarHBondContact O-N 3.39Å
531	L	44.3	Very low	49.2	Very low	87 Å²	87	96.2 Å²	96.2	46%	0.455	52%	0.521	S	S	.	.	S	Bend	trans	-99.5	107.6	177.3	-81	151.2	0	0	0	109.7	D533	L531-D533 PolarHBondContact O-N 3.39Å
532	S	42.2	Very low	48.4	Very low	84 Å²	84	96.4 Å²	96.4	59%	0.587	53%	0.527	S	S	*	.			trans	-60.1	130.8	177	49.4	0	0	0	0	111.6	D534	S532-D534 PolarHBondContact O-N 2.6Å
533	D	45.8	Very low	47.8	Very low	86 Å²	86	101.1 Å²	101.1	46%	0.46	55%	0.545	S	S	.	.			trans	-69.5	41.7	-176.5	-78.6	-31.8	0	0	0	114.2	L531 E535	L531-D533 PolarHBondContact O-N 3.39Å; D533-E535 PolarHBondContact O-N 2.7Å; D533-E535 VanDerWaalsContact O-N 3.17Å
534	D	45.8	Very low	46.9	Very low	130 Å²	130	101.5 Å²	101.5	70%	0.695	55%	0.552	S	S	*	*	G	3₁₀ helix	trans	-75.8	3.6	177.3	-71.9	-32.2	0	0	0	113.3	S532 Y536	S532-D534 PolarHBondContact O-N 2.6Å; D534-Y536 PolarHBondContact O-N 3.18Å
535	E	46.6	Very low	46.1	Very low	79 Å²	79	106.7 Å²	106.7	37%	0.369	58%	0.579	S	S	.	*	G	3₁₀ helix	trans	-85.1	0.9	-175.8	-156.7	168.4	-168	0	0	114.4	R38 R404 D533	R38-E535 IonicContact NH1-OE1 3.52Å; R38-E535 PolarHBondContact NH1-OE1 2.72Å; R404-E535 IonicContact NH2-OE2 3.65Å; R404-E535 PolarHBondContact NH2-OE2 3.06Å; R404-E535 VanDerWaalsContact NH2-OE2 3.16Å; D533-E535 PolarHBondContact O-N 2.7Å; D533-E535 VanDerWaalsContact O-N 3.17Å
536	Y	42.3	Very low	45.1	Very low	123 Å²	123	110.5 Å²	110.5	48%	0.482	60%	0.604	S	S	.	*	G	3₁₀ helix	trans	-120.2	10	-177	-68.3	-72.1	0	0	0	116.3	H285 I288 D534	H285-Y536 PolarHBondContact CE1-OH 3.18Å; I288-Y536 HydrophobicContact CD1-CD1 4.28Å; I288-Y536 HydrophobicContact CD1-CE1 3.74Å; D534-Y536 PolarHBondContact O-N 3.18Å
537	V	34.7	Very low	44.7	Very low	115 Å²	115	113 Å²	113	70%	0.697	60%	0.598	S	S	*	*			trans	-105.6	72.1	164.4	-170.2	0	0	0	0	107.6
538	H	32.8	Very low	44	Very low	260 Å²	260	110.9 Å²	110.9	100%	1.204	59%	0.586	S	S	*	*			trans	178.5	0	149.4	-88.2	-46.1	0	0	0	113.1

Retrieved 538 of 538 residues in 463.2 ms (Link to these results)

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