A0A087Y3U0_POEFO Loading...

Cullin-5

AlphaFold DB , UniProt , Accession A0A087Y3U0, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 781 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M45.3Very low38.9Very low250 Ų250148.5 Ų148.5100%1.23282%0.821SS**  0107.20-76.1-178-170.400108.5
2A28.3Very low39.8Very low102 Ų102141.9 Ų141.984%0.84379%0.793SS**  trans-166.6121.5162.500000107.6
3T37Very low41Very low135 Ų135136.2 Ų136.283%0.82876%0.759SS**  trans-57.7-178.2161.940.30000111.9
4P43.7Very low42.5Very low107 Ų107134.4 Ų134.470%0.69574%0.742SS**  cis-132.8146.9-30.632.1-14.7000111.8
5N31.6Very low44.4Very low141 Ų141126.7 Ų126.775%0.75470%0.698SS**  trans-151.915.5173.3-109.4-13.2000118.3
6L35.6Very low46.1Very low185 Ų185124.1 Ų124.197%0.96968%0.679SS**THydrogen-bonded Turntrans-96.411.8-177.7-82.3156.2000115.3
7L38.6Very low47.7Very low174 Ų174122.8 Ų122.891%0.91167%0.671SS**THydrogen-bonded Turntrans-114.815.7177.8-89.5160.1000114.4
8K37Very low49.2Very low170 Ų170118.6 Ų118.674%0.73965%0.646SS**  trans-11782.7171.2-78.7-176.8175.5179.10109.8
9N39.3Very low50.7Low113 Ų113113.4 Ų113.460%0.60462%0.616SS**  trans-175.934.5155.1-93.3-9.4000112G11N9-G11 PolarHBondContact O-N 2.86Å; N9-G11 VanDerWaalsContact O-N 3.16Å
10K42.7Very low52.1Low200 Ų200113.8 Ų113.887%0.8762%0.617SS**THydrogen-bonded Turntrans-75.697.8157.4-90.1-169.9169.9-167.30106.8
11G48.3Very low53.4Low57 Ų57113.4 Ų113.459%0.58861%0.614SS**THydrogen-bonded Turntrans132.38.5173.300000118.1N9N9-G11 PolarHBondContact O-N 2.86Å; N9-G11 VanDerWaalsContact O-N 3.16Å
12S50.3Low55Low69 Ų69101.5 Ų101.548%0.48356%0.555SS.*SBendtrans-99.6-2.1-177.981.20000116
13L55Low57.5Low68 Ų68101.7 Ų101.736%0.35653%0.534SS..  trans-124.7104.7178.3-81.4156.7000107.6K18L13-K18 HydrophobicContact CD2-CG 4.28Å
14Q62.4Low59.7Low110 Ų11098.4 Ų98.451%0.51452%0.515SS..  trans-94.6152.4176.4-62.1-165.22.100110.6E16 D17Q14-E16 PolarHBondContact O-N 3.18Å; Q14-D17 PolarHBondContact N-OD2 2.93Å; Q14-D17 PolarHBondContact O-N 2.84Å; Q14-D17 VanDerWaalsContact O-N 3.17Å
15F70.6Confident61.6Low20 Ų2094.1 Ų94.19%0.08849%0.486CS..Hα-helixtrans-47.7-41.8173165.6-97.2000112.2D17 K18 W19 V50 D54 K60 I61 A64F15-D17 VanDerWaalsContact C-N 3.32Å; F15-D17 PolarHBondContact O-N 2.7Å; F15-K18 PolarHBondContact O-N 3Å; F15-W19 HydrophobicContact CD1-CB 4.4Å; F15-W19 HydrophobicContact CD2-CB 4.25Å; F15-W19 HydrophobicContact CE1-CB 4Å; F15-W19 HydrophobicContact CE1-CG 4.02Å; F15-W19 HydrophobicContact CE2-CB 3.81Å; F15-W19 AromaticContact CE2-CD2 3.73Å; F15-W19 HydrophobicContact CE2-CD2 3.73Å; F15-W19 AromaticContact CE2-CE3 3.67Å; F15-W19 HydrophobicContact CE2-CE3 3.67Å; F15-W19 AromaticContact CE2-CG 3.8Å; F15-W19 HydrophobicContact CE2-CG 3.8Å; F15-W19 HydrophobicContact CZ-CB 3.69Å; F15-W19 AromaticContact CZ-CD1 3.88Å; F15-W19 AromaticContact CZ-CD2 3.59Å; F15-W19 HydrophobicContact CZ-CD2 3.59Å; F15-W19 HydrophobicContact CZ-CE3 4.03Å; F15-W19 AromaticContact CZ-CG 3.42Å; F15-W19 HydrophobicContact CZ-CG 3.42Å; F15-W19 VanDerWaalsContact CZ-CG 3.42Å; F15-W19 VanDerWaalsContact O-CB 3.29Å; F15-W19 WeakPolarHBondContact O-CB 3.25Å; F15-W19 PolarHBondContact O-N 2.69Å; F15-V50 HydrophobicContact CB-CG1 4.28Å; F15-V50 HydrophobicContact CD2-CG1 4.18Å; F15-D54 PolarHBondContact N-OD2 3.16Å; F15-K60 HydrophobicContact CB-CB 4.49Å; F15-K60 HydrophobicContact CB-CD 3.88Å; F15-K60 HydrophobicContact CD1-CB 3.88Å; F15-K60 HydrophobicContact CD1-CD 3.67Å; F15-K60 HydrophobicContact CD1-CG 4.4Å; F15-K60 HydrophobicContact CD2-CB 3.83Å; F15-K60 HydrophobicContact CE1-CB 3.99Å; F15-K60 HydrophobicContact CE1-CD 4.38Å; F15-K60 HydrophobicContact CE2-CB 3.96Å; F15-K60 HydrophobicContact CG-CB 3.79Å; F15-K60 HydrophobicContact CG-CD 3.82Å; F15-K60 HydrophobicContact CZ-CB 4.02Å; F15-I61 HydrophobicContact CD2-CG1 3.7Å; F15-I61 HydrophobicContact CE2-CB 4.28Å; F15-I61 HydrophobicContact CE2-CG1 3.56Å; F15-A64 HydrophobicContact CZ-CB 3.98Å
16E72.6Confident64Low84 Ų8487.4 Ų87.439%0.39345%0.45SS..Hα-helixtrans-59.6-36.7-177.4-69.778.5-175.200113Q14 K18 K60Q14-E16 PolarHBondContact O-N 3.18Å; E16-K18 VanDerWaalsContact C-N 3.3Å; E16-K18 PolarHBondContact O-N 3.21Å; E16-K60 IonicContact OE1-NZ 3.23Å; E16-K60 PolarHBondContact OE1-NZ 3.32Å; E16-K60 IonicContact OE2-NZ 3.74Å; E16-K60 PolarHBondContact OE2-NZ 2.86Å
17D72.3Confident66.2Low103 Ų10380.7 Ų80.755%0.55142%0.415SS*.Hα-helixtrans-75-21.7-178.1-57.8-45.7000113.3Q14 F15Q14-D17 PolarHBondContact N-OD2 2.93Å; Q14-D17 PolarHBondContact O-N 2.84Å; Q14-D17 VanDerWaalsContact O-N 3.17Å; F15-D17 VanDerWaalsContact C-N 3.32Å; F15-D17 PolarHBondContact O-N 2.7Å
18K74.7Confident68.3Low47 Ų4775.7 Ų75.720%0.20439%0.386CS..Hα-helixtrans-110.8-28.2-170.5-74.6-65.9-166.3166.20112.5L13 F15 E16 D20 L21 M22 D46 V50L13-K18 HydrophobicContact CD2-CG 4.28Å; F15-K18 PolarHBondContact O-N 3Å; E16-K18 VanDerWaalsContact C-N 3.3Å; E16-K18 PolarHBondContact O-N 3.21Å; K18-D20 PolarHBondContact O-N 2.98Å; K18-L21 PolarHBondContact O-N 3.3Å; K18-M22 HydrophobicContact CB-CE 3.62Å; K18-M22 WeakPolarHBondContact O-CE 3.34Å; K18-M22 WeakPolarHBondContact O-CG 3.44Å; K18-M22 PolarHBondContact O-N 3.38Å; K18-M22 VanDerWaalsContact O-N 3.1Å; K18-D46 IonicContact NZ-OD1 3.38Å; K18-D46 PolarHBondContact NZ-OD1 3.34Å; K18-V50 HydrophobicContact CB-CG2 3.7Å; K18-V50 HydrophobicContact CG-CG2 4.19Å
19W78.6Confident70.4Confident20 Ų2068 Ų688%0.07635%0.353CS..Hα-helixtrans-65.7-36.2177.3-174.1-110.9000112.8F15 L21 M22 R23 I61 A64F15-W19 HydrophobicContact CD1-CB 4.4Å; F15-W19 HydrophobicContact CD2-CB 4.25Å; F15-W19 HydrophobicContact CE1-CB 4Å; F15-W19 HydrophobicContact CE1-CG 4.02Å; F15-W19 HydrophobicContact CE2-CB 3.81Å; F15-W19 AromaticContact CE2-CD2 3.73Å; F15-W19 HydrophobicContact CE2-CD2 3.73Å; F15-W19 AromaticContact CE2-CE3 3.67Å; F15-W19 HydrophobicContact CE2-CE3 3.67Å; F15-W19 AromaticContact CE2-CG 3.8Å; F15-W19 HydrophobicContact CE2-CG 3.8Å; F15-W19 HydrophobicContact CZ-CB 3.69Å; F15-W19 AromaticContact CZ-CD1 3.88Å; F15-W19 AromaticContact CZ-CD2 3.59Å; F15-W19 HydrophobicContact CZ-CD2 3.59Å; F15-W19 HydrophobicContact CZ-CE3 4.03Å; F15-W19 AromaticContact CZ-CG 3.42Å; F15-W19 HydrophobicContact CZ-CG 3.42Å; F15-W19 VanDerWaalsContact CZ-CG 3.42Å; F15-W19 VanDerWaalsContact O-CB 3.29Å; F15-W19 WeakPolarHBondContact O-CB 3.25Å; F15-W19 PolarHBondContact O-N 2.69Å; W19-L21 PolarHBondContact O-N 2.81Å; W19-M22 HydrophobicContact CE3-CB 4.28Å; W19-M22 PolarHBondContact O-N 2.72Å; W19-M22 VanDerWaalsContact O-N 3.11Å; W19-R23 HydrophobicContact CZ2-CB 4.43Å; W19-R23 HydrophobicContact CZ2-CG 4.47Å; W19-R23 VanDerWaalsContact O-CB 3.29Å; W19-R23 WeakPolarHBondContact O-CB 3.5Å; W19-R23 PolarHBondContact O-N 3.23Å; W19-I61 HydrophobicContact CZ3-CG2 4.2Å; W19-A64 HydrophobicContact CD2-CB 4.23Å; W19-A64 VanDerWaalsContact CE2-CB 3.46Å; W19-A64 HydrophobicContact CH2-CB 3.89Å; W19-A64 HydrophobicContact CZ2-CB 3.28Å
20D78.6Confident72.4Confident121 Ų12162.6 Ų62.665%0.64732%0.324SS*.Hα-helixtrans-62.6-27176.7-76.9-19.8000112.9K18 P24K18-D20 PolarHBondContact O-N 2.98Å; D20-P24 WeakPolarHBondContact O-CD 3.4Å
21L78Confident74.2Confident105 Ų10559.2 Ų59.255%0.5531%0.306SS..Hα-helixtrans-84.5-34.1174.5-61.9172.5000112.2K18 W19K18-L21 PolarHBondContact O-N 3.3Å; W19-L21 PolarHBondContact O-N 2.81Å
22M79.5Confident75.6Confident0 Ų060.8 Ų60.80%030%0.298CS..Hα-helixtrans-77.6-42.2-180-71.7-172.7-107.400113.3K18 W19 I25 V26 L43 D46 V47 V50K18-M22 HydrophobicContact CB-CE 3.62Å; K18-M22 WeakPolarHBondContact O-CE 3.34Å; K18-M22 WeakPolarHBondContact O-CG 3.44Å; K18-M22 PolarHBondContact O-N 3.38Å; K18-M22 VanDerWaalsContact O-N 3.1Å; W19-M22 HydrophobicContact CE3-CB 4.28Å; W19-M22 PolarHBondContact O-N 2.72Å; W19-M22 VanDerWaalsContact O-N 3.11Å; M22-I25 WeakPolarHBondContact O-CA 3.18Å; M22-I25 WeakPolarHBondContact O-CB 3.45Å; M22-I25 PolarHBondContact O-N 3.25Å; M22-V26 WeakPolarHBondContact O-CG2 3.4Å; M22-V26 PolarHBondContact O-N 2.81Å; M22-L43 HydrophobicContact CB-CD1 3.85Å; M22-L43 HydrophobicContact CG-CD1 3.76Å; M22-L43 HydrophobicContact SD-CD1 4.15Å; M22-D46 HydrophobicContact CE-CB 3.69Å; M22-D46 HydrophobicContact CG-CB 3.83Å; M22-D46 HydrophobicContact SD-CB 3.73Å; M22-V47 HydrophobicContact SD-CG2 3.71Å; M22-V50 HydrophobicContact CE-CB 4.46Å; M22-V50 HydrophobicContact CE-CG2 3.65Å
23R81.9Confident77.2Confident107 Ų10761.9 Ų61.940%0.40430%0.295SS..Hα-helixtrans-54.5-43.6-173-174.5-179.1-171.3-160.31113.8W19 I25 V26 L27 D68W19-R23 HydrophobicContact CZ2-CB 4.43Å; W19-R23 HydrophobicContact CZ2-CG 4.47Å; W19-R23 VanDerWaalsContact O-CB 3.29Å; W19-R23 WeakPolarHBondContact O-CB 3.5Å; W19-R23 PolarHBondContact O-N 3.23Å; R23-I25 VanDerWaalsContact C-N 3.27Å; R23-I25 PolarHBondContact O-N 2.87Å; R23-V26 PolarHBondContact O-N 3.43Å; R23-L27 HydrophobicContact CG-CD1 4.16Å; R23-L27 HydrophobicContact CG-CG 4.41Å; R23-L27 WeakPolarHBondContact O-CB 3.42Å; R23-L27 WeakPolarHBondContact O-CG 3.45Å; R23-L27 PolarHBondContact O-N 3.44Å; R23-D68 IonicContact CZ-OD1 2.97Å; R23-D68 IonicContact NE-OD1 2.78Å; R23-D68 PolarHBondContact NE-OD1 2.87Å; R23-D68 IonicContact NE-OD2 3.29Å; R23-D68 PolarHBondContact NE-OD2 3.16Å; R23-D68 IonicContact NH2-OD1 2.96Å; R23-D68 PolarHBondContact NH2-OD1 3.15Å
24P83.3Confident78.3Confident66 Ų6663.2 Ų63.243%0.42932%0.316SS..Hα-helixtrans-62.1-33.6175.9-23.234.8000113.2D20 K28D20-P24 WeakPolarHBondContact O-CD 3.4Å; P24-K28 WeakPolarHBondContact O-CB 3.46Å; P24-K28 VanDerWaalsContact O-CG 3.26Å; P24-K28 WeakPolarHBondContact O-CG 3.44Å; P24-K28 PolarHBondContact O-N 2.81Å; P24-K28 VanDerWaalsContact O-N 3.08Å
25I82.5Confident79.2Confident16 Ų1659.2 Ų59.28%0.08230%0.299CS..Hα-helixtrans-73.5-41.8177.9-52.9174.4000109.6M22 R23 K28 L29 V35 Q39 L43M22-I25 WeakPolarHBondContact O-CA 3.18Å; M22-I25 WeakPolarHBondContact O-CB 3.45Å; M22-I25 PolarHBondContact O-N 3.25Å; R23-I25 VanDerWaalsContact C-N 3.27Å; R23-I25 PolarHBondContact O-N 2.87Å; I25-K28 WeakPolarHBondContact O-CB 3.32Å; I25-K28 PolarHBondContact O-N 3.06Å; I25-L29 WeakPolarHBondContact O-CG 3.31Å; I25-L29 PolarHBondContact O-N 3.4Å; I25-V35 HydrophobicContact CG2-CG1 3.84Å; I25-Q39 HydrophobicContact CD1-CB 4.11Å; I25-Q39 HydrophobicContact CD1-CG 4.3Å; I25-Q39 HydrophobicContact CG1-CB 4.46Å; I25-Q39 HydrophobicContact CG2-CB 4.26Å; I25-L43 HydrophobicContact CG2-CB 4.32Å; I25-L43 HydrophobicContact CG2-CD2 3.9Å
26V81.8Confident80Confident0 Ų061.9 Ų61.90%032%0.317CS..Hα-helixtrans-61.2-44.3174.9174.40000111.6M22 R23 K28 L29 L30 L43 L65 L107 F111M22-V26 WeakPolarHBondContact O-CG2 3.4Å; M22-V26 PolarHBondContact O-N 2.81Å; R23-V26 PolarHBondContact O-N 3.43Å; V26-K28 PolarHBondContact O-N 3.19Å; V26-L29 PolarHBondContact O-N 2.95Å; V26-L30 HydrophobicContact CG1-CD1 4.21Å; V26-L30 WeakPolarHBondContact O-CG 3.18Å; V26-L30 PolarHBondContact O-N 3.12Å; V26-L43 HydrophobicContact CG2-CD1 4.11Å; V26-L65 HydrophobicContact CG1-CD1 3.72Å; V26-L107 HydrophobicContact CG1-CD1 4.35Å; V26-F111 HydrophobicContact CG2-CE2 4.48Å; V26-F111 HydrophobicContact CG2-CZ 3.84Å
27L82.5Confident80.4Confident45 Ų4567.1 Ų67.124%0.23634%0.339CS..Hα-helixtrans-64.8-37.8175.8-71.3173.8000112.3R23 L30 R31 D68R23-L27 HydrophobicContact CG-CD1 4.16Å; R23-L27 HydrophobicContact CG-CG 4.41Å; R23-L27 WeakPolarHBondContact O-CB 3.42Å; R23-L27 WeakPolarHBondContact O-CG 3.45Å; R23-L27 PolarHBondContact O-N 3.44Å; L27-L30 PolarHBondContact O-N 3.07Å; L27-R31 WeakPolarHBondContact O-CB 3.38Å; L27-R31 VanDerWaalsContact O-CG 3.3Å; L27-R31 WeakPolarHBondContact O-CG 3.34Å; L27-R31 PolarHBondContact O-N 2.94Å; L27-D68 HydrophobicContact CD2-CB 4.29Å
28K82.8Confident80.9Confident69 Ų6969 Ų6930%0.334%0.344SS..Hα-helixtrans-62.3-42.5173.1-79.9177.2176.3-174.10112P24 I25 V26 R31 Q32 E33 V35P24-K28 WeakPolarHBondContact O-CB 3.46Å; P24-K28 VanDerWaalsContact O-CG 3.26Å; P24-K28 WeakPolarHBondContact O-CG 3.44Å; P24-K28 PolarHBondContact O-N 2.81Å; P24-K28 VanDerWaalsContact O-N 3.08Å; I25-K28 WeakPolarHBondContact O-CB 3.32Å; I25-K28 PolarHBondContact O-N 3.06Å; V26-K28 PolarHBondContact O-N 3.19Å; K28-R31 PolarHBondContact O-N 3.36Å; K28-Q32 PolarHBondContact O-N 3.01Å; K28-Q32 VanDerWaalsContact O-N 3.14Å; K28-E33 HydrophobicContact CB-CB 4.06Å; K28-E33 HydrophobicContact CG-CB 4.06Å; K28-E33 WeakPolarHBondContact CG-OE2 3.39Å; K28-E33 PolarHBondContact O-N 3.39Å; K28-V35 HydrophobicContact CB-CG2 3.82Å
29L81.6Confident81.3Confident7 Ų769 Ų694%0.03735%0.345CS..Hα-helixtrans-61.5-52.6174.7-68.1172.5000110.6I25 V26 R31 Q32 V35 W40 L43 Q103 I106 L107 P110I25-L29 WeakPolarHBondContact O-CG 3.31Å; I25-L29 PolarHBondContact O-N 3.4Å; V26-L29 PolarHBondContact O-N 2.95Å; L29-R31 PolarHBondContact O-N 3.37Å; L29-Q32 PolarHBondContact O-N 3.36Å; L29-V35 HydrophobicContact CD2-CB 4.22Å; L29-V35 HydrophobicContact CD2-CG2 3.66Å; L29-V35 HydrophobicContact CG-CG2 4.04Å; L29-W40 HydrophobicContact CD1-CH2 4.27Å; L29-W40 HydrophobicContact CD1-CZ2 4.41Å; L29-W40 HydrophobicContact CD2-CH2 3.89Å; L29-W40 HydrophobicContact CD2-CZ2 3.31Å; L29-L43 HydrophobicContact CD1-CD2 3.69Å; L29-Q103 PolarHBondContact O-NE2 3.35Å; L29-Q103 PolarHBondContact O-OE1 3.35Å; L29-I106 HydrophobicContact CD2-CG2 4.28Å; L29-L107 HydrophobicContact CB-CD1 3.99Å; L29-L107 HydrophobicContact CD1-CD1 4.32Å; L29-P110 HydrophobicContact CD1-CG 4.36Å
30L80.1Confident81.5Confident1 Ų170.7 Ų70.71%0.00535%0.351CS..Hα-helixtrans-55.4-37.7178.1-75.4169.6000113.2V26 L27 Q32 D68 I69 F72 L107 M139V26-L30 HydrophobicContact CG1-CD1 4.21Å; V26-L30 WeakPolarHBondContact O-CG 3.18Å; V26-L30 PolarHBondContact O-N 3.12Å; L27-L30 PolarHBondContact O-N 3.07Å; L30-Q32 VanDerWaalsContact C-N 3.33Å; L30-D68 HydrophobicContact CD1-CB 4.27Å; L30-I69 HydrophobicContact CD2-CG1 4.26Å; L30-F72 HydrophobicContact CB-CD2 4.36Å; L30-F72 WeakPolarHBondContact O-CE2 3.39Å; L30-F72 VanDerWaalsContact O-CZ 3.27Å; L30-F72 WeakPolarHBondContact O-CZ 3.33Å; L30-L107 HydrophobicContact CD2-CD2 3.66Å; L30-L107 HydrophobicContact CG-CD1 4.38Å; L30-L107 HydrophobicContact CG-CD2 4.3Å; L30-M139 HydrophobicContact CD2-CE 4.02Å
31R81.5Confident81.6Confident129 Ų12971.7 Ų71.749%0.48735%0.35SS..THydrogen-bonded Turntrans-85-0.3179.5-67.1176.3-174.6177.53.3114.7L27 K28 L29 E33L27-R31 WeakPolarHBondContact O-CB 3.38Å; L27-R31 VanDerWaalsContact O-CG 3.3Å; L27-R31 WeakPolarHBondContact O-CG 3.34Å; L27-R31 PolarHBondContact O-N 2.94Å; K28-R31 PolarHBondContact O-N 3.36Å; L29-R31 PolarHBondContact O-N 3.37Å; R31-E33 HydrophobicContact CB-CG 3.98Å; R31-E33 WeakPolarHBondContact CD-OE1 3.49Å; R31-E33 PolarHBondContact O-N 2.7Å
32Q77.9Confident81.9Confident90 Ų9069.6 Ų69.642%0.42134%0.339SS..THydrogen-bonded Turntrans60.230.1-173.5-35.6-158.5-47.100114K28 L29 L30 K99 Q103K28-Q32 PolarHBondContact O-N 3.01Å; K28-Q32 VanDerWaalsContact O-N 3.14Å; L29-Q32 PolarHBondContact O-N 3.36Å; L30-Q32 VanDerWaalsContact C-N 3.33Å; Q32-K99 PolarHBondContact NE2-O 3.1Å; Q32-Q103 HydrophobicContact CG-CG 4.06Å; Q32-Q103 VanDerWaalsContact CG-NE2 3.32Å
33E82.4Confident82Confident91 Ų9169.6 Ų69.643%0.42534%0.339SS..  trans-78.4155.5174.2-65.3176.6-157.500110.7K28 R31 V35K28-E33 HydrophobicContact CB-CB 4.06Å; K28-E33 HydrophobicContact CG-CB 4.06Å; K28-E33 WeakPolarHBondContact CG-OE2 3.39Å; K28-E33 PolarHBondContact O-N 3.39Å; R31-E33 HydrophobicContact CB-CG 3.98Å; R31-E33 WeakPolarHBondContact CD-OE1 3.49Å; R31-E33 PolarHBondContact O-N 2.7Å; E33-V35 PolarHBondContact O-N 3.48Å
34A77.8Confident82Confident96 Ų9668.9 Ų68.979%0.79334%0.339SS*.  trans-66.5121.6-178.100000111.6
35V82.4Confident81.9Confident26 Ų2668.6 Ų68.616%0.15834%0.339CS..  trans-111126.2175.8-176.40000109.4I25 K28 L29 E33 Q39 W40I25-V35 HydrophobicContact CG2-CG1 3.84Å; K28-V35 HydrophobicContact CB-CG2 3.82Å; L29-V35 HydrophobicContact CD2-CB 4.22Å; L29-V35 HydrophobicContact CD2-CG2 3.66Å; L29-V35 HydrophobicContact CG-CG2 4.04Å; E33-V35 PolarHBondContact O-N 3.48Å; V35-Q39 HydrophobicContact CG1-CB 3.53Å; V35-W40 HydrophobicContact CG1-CG 4.22Å
36T86.3Confident81.8Confident76 Ų7668.6 Ų68.647%0.46634%0.339SS..  trans-73.5157.6-178.664.40000111.6Q38 Q39 W40T36-Q38 PolarHBondContact O-N 3.31Å; T36-Q39 PolarHBondContact O-N 3.45Å; T36-Q39 VanDerWaalsContact O-N 3.11Å; T36-Q39 WeakPolarHBondContact OG1-CG 3.47Å; T36-Q39 PolarHBondContact OG1-N 3.39Å; T36-Q39 PolarHBondContact OG1-OE1 3.44Å; T36-W40 PolarHBondContact O-N 2.78Å
37K82.1Confident81.8Confident194 Ų19468.6 Ų68.684%0.84334%0.339SS*.Hα-helixtrans-56.2-33.6175.9-69.7-176-179.7178.80112.7W40 F41K37-W40 PolarHBondContact O-N 3.41Å; K37-F41 PolarHBondContact O-N 3.26Å
38Q81.9Confident81.6Confident142 Ų14270.5 Ų70.566%0.66435%0.347SS*.Hα-helixtrans-68-47.3176.7-170.8167.20.300111.1T36 W40 F41 D42T36-Q38 PolarHBondContact O-N 3.31Å; Q38-W40 VanDerWaalsContact C-N 3.27Å; Q38-W40 PolarHBondContact O-N 3.26Å; Q38-F41 WeakPolarHBondContact O-CB 3.42Å; Q38-F41 PolarHBondContact O-N 3Å; Q38-D42 WeakPolarHBondContact O-CB 3.45Å; Q38-D42 PolarHBondContact O-N 3.39Å
39Q83.1Confident81.4Confident47 Ų4768 Ų6822%0.2234%0.34CS..Hα-helixtrans-60.1-35.6174.7-74.4168.9-25.600113.1I25 V35 T36 L43I25-Q39 HydrophobicContact CD1-CB 4.11Å; I25-Q39 HydrophobicContact CD1-CG 4.3Å; I25-Q39 HydrophobicContact CG1-CB 4.46Å; I25-Q39 HydrophobicContact CG2-CB 4.26Å; V35-Q39 HydrophobicContact CG1-CB 3.53Å; T36-Q39 PolarHBondContact O-N 3.45Å; T36-Q39 VanDerWaalsContact O-N 3.11Å; T36-Q39 WeakPolarHBondContact OG1-CG 3.47Å; T36-Q39 PolarHBondContact OG1-N 3.39Å; T36-Q39 PolarHBondContact OG1-OE1 3.44Å; Q39-L43 VanDerWaalsContact O-CB 3.29Å; Q39-L43 WeakPolarHBondContact O-CB 3.45Å; Q39-L43 PolarHBondContact O-N 3.5Å
40W82.5Confident81.2Confident56 Ų5668 Ų6821%0.21234%0.339CS..Hα-helixtrans-62-50.4170.9-86.598.8000111.5L29 V35 T36 K37 Q38 D42 L43 F44 I106 K109 P110L29-W40 HydrophobicContact CD1-CH2 4.27Å; L29-W40 HydrophobicContact CD1-CZ2 4.41Å; L29-W40 HydrophobicContact CD2-CH2 3.89Å; L29-W40 HydrophobicContact CD2-CZ2 3.31Å; V35-W40 HydrophobicContact CG1-CG 4.22Å; T36-W40 PolarHBondContact O-N 2.78Å; K37-W40 PolarHBondContact O-N 3.41Å; Q38-W40 VanDerWaalsContact C-N 3.27Å; Q38-W40 PolarHBondContact O-N 3.26Å; W40-D42 VanDerWaalsContact C-N 3.34Å; W40-D42 PolarHBondContact O-N 3.16Å; W40-L43 PolarHBondContact O-N 3.39Å; W40-F44 HydrophobicContact CE3-CD2 4.32Å; W40-F44 AromaticContact CE3-CE2 3.66Å; W40-F44 HydrophobicContact CE3-CE2 3.66Å; W40-F44 HydrophobicContact CE3-CZ 4.46Å; W40-F44 HydrophobicContact CZ3-CE2 4.19Å; W40-F44 WeakPolarHBondContact O-CD2 3.44Å; W40-F44 PolarHBondContact O-N 3.48Å; W40-I106 HydrophobicContact CH2-CG2 3.63Å; W40-I106 HydrophobicContact CZ2-CG2 3.75Å; W40-K109 HydrophobicContact CZ3-CB 4.09Å; W40-P110 HydrophobicContact CE3-CG 3.88Å; W40-P110 HydrophobicContact CH2-CG 4.22Å; W40-P110 HydrophobicContact CZ3-CG 3.38Å
41F82.5Confident81Confident142 Ų14268.3 Ų68.362%0.62334%0.342SS*.Hα-helixtrans-60.7-43.1179.2-176.3-93.4000112.3K37 Q38 F44 S45K37-F41 PolarHBondContact O-N 3.26Å; Q38-F41 WeakPolarHBondContact O-CB 3.42Å; Q38-F41 PolarHBondContact O-N 3Å; F41-F44 PolarHBondContact O-N 3.18Å; F41-S45 VanDerWaalsContact O-CB 3.32Å; F41-S45 WeakPolarHBondContact O-CB 3.49Å; F41-S45 PolarHBondContact O-N 3.23Å
42D82.8Confident80.7Confident61 Ų6166.6 Ų66.633%0.32634%0.342SS..Hα-helixtrans-61.4-45.5177.4-62.2-23.9000110.2Q38 W40 F44 S45 D46Q38-D42 WeakPolarHBondContact O-CB 3.45Å; Q38-D42 PolarHBondContact O-N 3.39Å; W40-D42 VanDerWaalsContact C-N 3.34Å; W40-D42 PolarHBondContact O-N 3.16Å; D42-F44 PolarHBondContact O-N 2.93Å; D42-S45 PolarHBondContact O-N 3.32Å; D42-D46 VanDerWaalsContact O-CB 3.28Å; D42-D46 WeakPolarHBondContact O-CB 3.34Å; D42-D46 VanDerWaalsContact O-CG 3.29Å; D42-D46 PolarHBondContact O-N 3.29Å
43L82.3Confident80.3Confident0 Ų068.4 Ų68.40%035%0.345CS..Hα-helixtrans-62.7-43.1176.3-174.264.5000112.4M22 I25 V26 L29 Q39 W40 V47 P110M22-L43 HydrophobicContact CB-CD1 3.85Å; M22-L43 HydrophobicContact CG-CD1 3.76Å; M22-L43 HydrophobicContact SD-CD1 4.15Å; I25-L43 HydrophobicContact CG2-CB 4.32Å; I25-L43 HydrophobicContact CG2-CD2 3.9Å; V26-L43 HydrophobicContact CG2-CD1 4.11Å; L29-L43 HydrophobicContact CD1-CD2 3.69Å; Q39-L43 VanDerWaalsContact O-CB 3.29Å; Q39-L43 WeakPolarHBondContact O-CB 3.45Å; Q39-L43 PolarHBondContact O-N 3.5Å; W40-L43 PolarHBondContact O-N 3.39Å; L43-V47 HydrophobicContact CD1-CG2 4.17Å; L43-V47 HydrophobicContact CG-CG2 4.45Å; L43-V47 WeakPolarHBondContact O-CB 3.49Å; L43-V47 WeakPolarHBondContact O-CG2 3.49Å; L43-V47 PolarHBondContact O-N 3.09Å; L43-P110 HydrophobicContact CD2-CB 3.66Å; L43-P110 HydrophobicContact CD2-CG 3.53Å; L43-P110 HydrophobicContact CG-CB 3.76Å; L43-P110 HydrophobicContact CG-CG 4.2Å
44F81.8Confident79.8Confident92 Ų9265.5 Ų65.540%0.40433%0.332SS..Hα-helixtrans-60.5-45.5174.2-87.2-76.3000112W40 F41 D42 H48 K109 P110W40-F44 HydrophobicContact CE3-CD2 4.32Å; W40-F44 AromaticContact CE3-CE2 3.66Å; W40-F44 HydrophobicContact CE3-CE2 3.66Å; W40-F44 HydrophobicContact CE3-CZ 4.46Å; W40-F44 HydrophobicContact CZ3-CE2 4.19Å; W40-F44 WeakPolarHBondContact O-CD2 3.44Å; W40-F44 PolarHBondContact O-N 3.48Å; F41-F44 PolarHBondContact O-N 3.18Å; D42-F44 PolarHBondContact O-N 2.93Å; F44-H48 VanDerWaalsContact O-CB 3.28Å; F44-H48 WeakPolarHBondContact O-CB 3.4Å; F44-H48 PolarHBondContact O-N 3.31Å; F44-K109 WeakPolarHBondContact CE1-O 3.35Å; F44-K109 HydrophobicContact CZ-CB 4.35Å; F44-K109 WeakPolarHBondContact CZ-O 3.23Å; F44-P110 VanDerWaalsContact CE1-CA 3.49Å
45S81.7Confident79.3Confident60 Ų6068.9 Ų68.942%0.4234%0.337SS..Hα-helixtrans-65.5-45.4-179-1780000111.6F41 D42 H48 A49F41-S45 VanDerWaalsContact O-CB 3.32Å; F41-S45 WeakPolarHBondContact O-CB 3.49Å; F41-S45 PolarHBondContact O-N 3.23Å; D42-S45 PolarHBondContact O-N 3.32Å; S45-H48 PolarHBondContact O-N 3.31Å; S45-A49 WeakPolarHBondContact O-CB 3.3Å; S45-A49 PolarHBondContact O-N 3.5Å
46D80.9Confident79Confident17 Ų1774.9 Ų74.99%0.09136%0.361CS..Hα-helixtrans-71.5-40-177.6-73.9-27.6000111.9K18 M22 D42 H48 A49 V50K18-D46 IonicContact NZ-OD1 3.38Å; K18-D46 PolarHBondContact NZ-OD1 3.34Å; M22-D46 HydrophobicContact CE-CB 3.69Å; M22-D46 HydrophobicContact CG-CB 3.83Å; M22-D46 HydrophobicContact SD-CB 3.73Å; D42-D46 VanDerWaalsContact O-CB 3.28Å; D42-D46 WeakPolarHBondContact O-CB 3.34Å; D42-D46 VanDerWaalsContact O-CG 3.29Å; D42-D46 PolarHBondContact O-N 3.29Å; D46-H48 VanDerWaalsContact C-N 3.34Å; D46-H48 PolarHBondContact O-N 3.12Å; D46-A49 PolarHBondContact O-N 3.03Å; D46-V50 WeakPolarHBondContact O-CG2 3.47Å; D46-V50 PolarHBondContact O-N 3.37Å
47V80.5Confident78.4Confident0 Ų071.3 Ų71.30%034%0.339CS..Hα-helixtrans-61.7-44.1171.9172.30000110.4M22 L43 C51 F111 L114M22-V47 HydrophobicContact SD-CG2 3.71Å; L43-V47 HydrophobicContact CD1-CG2 4.17Å; L43-V47 HydrophobicContact CG-CG2 4.45Å; L43-V47 WeakPolarHBondContact O-CB 3.49Å; L43-V47 WeakPolarHBondContact O-CG2 3.49Å; L43-V47 PolarHBondContact O-N 3.09Å; V47-C51 VanDerWaalsContact O-CB 3.31Å; V47-C51 WeakPolarHBondContact O-CB 3.49Å; V47-C51 PolarHBondContact O-N 3.46Å; V47-C51 PolarHBondContact O-SG 3.4Å; V47-F111 HydrophobicContact CG1-CD1 3.92Å; V47-F111 HydrophobicContact CG2-CD1 3.82Å; V47-F111 HydrophobicContact CG2-CE1 3.63Å; V47-F111 HydrophobicContact CG2-CZ 4.4Å; V47-L114 HydrophobicContact CG1-CB 4.42Å
48H79.2Confident78.1Confident84 Ų8462.5 Ų62.539%0.38930%0.302SS..Hα-helixtrans-63.5-41.9177.2-177.8-81.5000111.9F44 S45 D46 L52 Q113F44-H48 VanDerWaalsContact O-CB 3.28Å; F44-H48 WeakPolarHBondContact O-CB 3.4Å; F44-H48 PolarHBondContact O-N 3.31Å; S45-H48 PolarHBondContact O-N 3.31Å; D46-H48 VanDerWaalsContact C-N 3.34Å; D46-H48 PolarHBondContact O-N 3.12Å; H48-L52 VanDerWaalsContact O-CB 3.32Å; H48-L52 WeakPolarHBondContact O-CB 3.35Å; H48-L52 PolarHBondContact O-N 2.94Å; H48-Q113 HydrophobicContact CB-CG 4.32Å
49A78.3Confident77.9Confident18 Ų1858.7 Ų58.715%0.14929%0.294CS..Hα-helixtrans-63.2-50.5177.700000111.8S45 D46 C51 L52 W53S45-A49 WeakPolarHBondContact O-CB 3.3Å; S45-A49 PolarHBondContact O-N 3.5Å; D46-A49 PolarHBondContact O-N 3.03Å; A49-C51 VanDerWaalsContact C-N 3.29Å; A49-C51 PolarHBondContact O-N 3.16Å; A49-L52 PolarHBondContact O-N 2.92Å; A49-L52 VanDerWaalsContact O-N 3.13Å; A49-W53 WeakPolarHBondContact O-CB 3.43Å; A49-W53 PolarHBondContact O-N 2.86Å
50V77.5Confident77.7Confident5 Ų559.6 Ų59.63%0.0330%0.297CS..Hα-helixtrans-65.7-34.2-178.9176.70000111.8F15 K18 M22 D46 L52 D54 I61F15-V50 HydrophobicContact CB-CG1 4.28Å; F15-V50 HydrophobicContact CD2-CG1 4.18Å; K18-V50 HydrophobicContact CB-CG2 3.7Å; K18-V50 HydrophobicContact CG-CG2 4.19Å; M22-V50 HydrophobicContact CE-CB 4.46Å; M22-V50 HydrophobicContact CE-CG2 3.65Å; D46-V50 WeakPolarHBondContact O-CG2 3.47Å; D46-V50 PolarHBondContact O-N 3.37Å; V50-L52 VanDerWaalsContact C-N 3.27Å; V50-L52 PolarHBondContact O-N 3.5Å; V50-D54 PolarHBondContact O-N 3.19Å; V50-I61 HydrophobicContact CB-CD1 3.83Å; V50-I61 HydrophobicContact CG1-CD1 3.5Å; V50-I61 VanDerWaalsContact CG1-CD1 3.5Å; V50-I61 HydrophobicContact CG1-CG1 4.12Å
51C75.8Confident77.6Confident8 Ų856.9 Ų56.95%0.05429%0.287CS..Hα-helixtrans-71.5-17.5176.6-670000114.4V47 A49 P58 Q113V47-C51 VanDerWaalsContact O-CB 3.31Å; V47-C51 WeakPolarHBondContact O-CB 3.49Å; V47-C51 PolarHBondContact O-N 3.46Å; V47-C51 PolarHBondContact O-SG 3.4Å; A49-C51 VanDerWaalsContact C-N 3.29Å; A49-C51 PolarHBondContact O-N 3.16Å; C51-P58 HydrophobicContact CB-CG 4.41Å; C51-Q113 HydrophobicContact CB-CG 4.26Å
52L74.5Confident77.5Confident93 Ų9352.6 Ų52.649%0.48727%0.269SS..Hα-helixtrans-107.9-27-173.3-153130.8000113.1H48 A49 V50H48-L52 VanDerWaalsContact O-CB 3.32Å; H48-L52 WeakPolarHBondContact O-CB 3.35Å; H48-L52 PolarHBondContact O-N 2.94Å; A49-L52 PolarHBondContact O-N 2.92Å; A49-L52 VanDerWaalsContact O-N 3.13Å; V50-L52 VanDerWaalsContact C-N 3.27Å; V50-L52 PolarHBondContact O-N 3.5Å
53W69.5Low77.4Confident129 Ų12955.2 Ų55.249%0.48928%0.279SS..Hα-helixtrans-109.6-16.6-173-61.2104.6000114.6A49A49-W53 WeakPolarHBondContact O-CB 3.43Å; A49-W53 PolarHBondContact O-N 2.86Å
54D72Confident77.4Confident30 Ų3055.9 Ų55.916%0.1629%0.285CS..  trans-116.8113.9175.3-178.5-1.9000110.7F15 V50 K56 G57 P58F15-D54 PolarHBondContact N-OD2 3.16Å; V50-D54 PolarHBondContact O-N 3.19Å; D54-K56 PolarHBondContact O-N 3.05Å; D54-K56 PolarHBondContact OD1-N 3.01Å; D54-G57 PolarHBondContact O-N 3.2Å; D54-G57 PolarHBondContact OD1-N 3.35Å; D54-G57 WeakPolarHBondContact OD2-CA 3.17Å; D54-G57 PolarHBondContact OD2-N 2.95Å; D54-P58 VanDerWaalsContact O-CD 3.27Å; D54-P58 WeakPolarHBondContact O-CD 3.16Å
55D67.9Low77.4Confident166 Ų16651.5 Ų51.589%0.88827%0.266SS*.THydrogen-bonded Turntrans-61.9-24.7179.8-68.4-30.7000112.8
56K75.2Confident77.5Confident153 Ų15353.5 Ų53.567%0.66527%0.267SS*.THydrogen-bonded Turntrans-100.7-6.1174.1-66.7-176.1-179.8179.10113D54 A59 K60D54-K56 PolarHBondContact O-N 3.05Å; D54-K56 PolarHBondContact OD1-N 3.01Å; K56-A59 PolarHBondContact O-N 3.06Å; K56-K60 WeakPolarHBondContact O-CG 3.23Å; K56-K60 PolarHBondContact O-N 3.41Å; K56-K60 VanDerWaalsContact O-N 3.13Å
57G73.8Confident77.6Confident0 Ų058 Ų580%029%0.287CS..Hα-helixtrans-56.4-49.6-176.500000113.8D54 A59 K60 I61D54-G57 PolarHBondContact O-N 3.2Å; D54-G57 PolarHBondContact OD1-N 3.35Å; D54-G57 WeakPolarHBondContact OD2-CA 3.17Å; D54-G57 PolarHBondContact OD2-N 2.95Å; G57-A59 PolarHBondContact O-N 3.01Å; G57-K60 PolarHBondContact O-N 3.13Å; G57-I61 WeakPolarHBondContact O-CG1 3.28Å; G57-I61 PolarHBondContact O-N 3.1Å
58P76.9Confident77.8Confident10 Ų1058.4 Ų58.47%0.06529%0.289CS..Hα-helixtrans-56.9-43.2178.4-28.434.9000114.3C51 D54 H62 L114 T117 L118C51-P58 HydrophobicContact CB-CG 4.41Å; D54-P58 VanDerWaalsContact O-CD 3.27Å; D54-P58 WeakPolarHBondContact O-CD 3.16Å; P58-H62 WeakPolarHBondContact O-CB 3.43Å; P58-H62 PolarHBondContact O-N 3.2Å; P58-L114 VanDerWaalsContact CA-CD1 3.47Å; P58-L114 HydrophobicContact CB-CD1 3.79Å; P58-L114 WeakPolarHBondContact O-CD1 3.49Å; P58-T117 HydrophobicContact CB-CG2 4.49Å; P58-T117 HydrophobicContact CG-CG2 3.76Å; P58-L118 HydrophobicContact CB-CD2 3.73Å; P58-L118 HydrophobicContact CB-CG 4.03Å
59A77.3Confident78.1Confident62 Ų6254.5 Ų54.551%0.51227%0.271SS..Hα-helixtrans-68.7-39.5179.100000111.9K56 G57 H62 Q63K56-A59 PolarHBondContact O-N 3.06Å; G57-A59 PolarHBondContact O-N 3.01Å; A59-H62 PolarHBondContact O-N 3.25Å; A59-Q63 WeakPolarHBondContact O-CB 3.25Å; A59-Q63 PolarHBondContact O-N 3.32Å
60K79.8Confident78.3Confident65 Ų6556.1 Ų56.128%0.28328%0.277SS..Hα-helixtrans-66.2-43.2176.2-71.5-177.4179.1-177.10112.5F15 E16 K56 G57 H62 Q63 A64F15-K60 HydrophobicContact CB-CB 4.49Å; F15-K60 HydrophobicContact CB-CD 3.88Å; F15-K60 HydrophobicContact CD1-CB 3.88Å; F15-K60 HydrophobicContact CD1-CD 3.67Å; F15-K60 HydrophobicContact CD1-CG 4.4Å; F15-K60 HydrophobicContact CD2-CB 3.83Å; F15-K60 HydrophobicContact CE1-CB 3.99Å; F15-K60 HydrophobicContact CE1-CD 4.38Å; F15-K60 HydrophobicContact CE2-CB 3.96Å; F15-K60 HydrophobicContact CG-CB 3.79Å; F15-K60 HydrophobicContact CG-CD 3.82Å; F15-K60 HydrophobicContact CZ-CB 4.02Å; E16-K60 IonicContact OE1-NZ 3.23Å; E16-K60 PolarHBondContact OE1-NZ 3.32Å; E16-K60 IonicContact OE2-NZ 3.74Å; E16-K60 PolarHBondContact OE2-NZ 2.86Å; K56-K60 WeakPolarHBondContact O-CG 3.23Å; K56-K60 PolarHBondContact O-N 3.41Å; K56-K60 VanDerWaalsContact O-N 3.13Å; G57-K60 PolarHBondContact O-N 3.13Å; K60-H62 VanDerWaalsContact C-N 3.35Å; K60-H62 PolarHBondContact O-N 3.01Å; K60-Q63 PolarHBondContact O-N 2.83Å; K60-A64 WeakPolarHBondContact O-CB 3.33Å; K60-A64 PolarHBondContact O-N 3.4Å
61I79.9Confident78.7Confident0 Ų059.7 Ų59.70%030%0.296CS..Hα-helixtrans-59-47.6173.8-70.2171.6000110.3F15 W19 V50 G57 Q63 A64 L65 F111 L114F15-I61 HydrophobicContact CD2-CG1 3.7Å; F15-I61 HydrophobicContact CE2-CB 4.28Å; F15-I61 HydrophobicContact CE2-CG1 3.56Å; W19-I61 HydrophobicContact CZ3-CG2 4.2Å; V50-I61 HydrophobicContact CB-CD1 3.83Å; V50-I61 HydrophobicContact CG1-CD1 3.5Å; V50-I61 VanDerWaalsContact CG1-CD1 3.5Å; V50-I61 HydrophobicContact CG1-CG1 4.12Å; G57-I61 WeakPolarHBondContact O-CG1 3.28Å; G57-I61 PolarHBondContact O-N 3.1Å; I61-Q63 VanDerWaalsContact C-N 3.34Å; I61-Q63 PolarHBondContact O-N 3.48Å; I61-A64 PolarHBondContact O-N 3.35Å; I61-L65 WeakPolarHBondContact O-CB 3.44Å; I61-L65 PolarHBondContact O-N 3.37Å; I61-F111 HydrophobicContact CG2-CD1 4.12Å; I61-F111 HydrophobicContact CG2-CE1 3.87Å; I61-L114 HydrophobicContact CB-CD1 4.05Å; I61-L114 HydrophobicContact CD1-CD1 4.41Å; I61-L114 HydrophobicContact CG2-CD1 4.05Å; I61-L114 HydrophobicContact CG2-CD2 3.79Å
62H79.9Confident79.1Confident51 Ų5160.3 Ų60.324%0.23630%0.298CS..Hα-helixtrans-61.9-40.9180-178.9-89.4000112.3P58 A59 K60 K66 L118P58-H62 WeakPolarHBondContact O-CB 3.43Å; P58-H62 PolarHBondContact O-N 3.2Å; A59-H62 PolarHBondContact O-N 3.25Å; K60-H62 VanDerWaalsContact C-N 3.35Å; K60-H62 PolarHBondContact O-N 3.01Å; H62-K66 WeakPolarHBondContact O-CB 3.22Å; H62-K66 PolarHBondContact O-N 2.97Å; H62-L118 HydrophobicContact CB-CD1 4.44Å
63Q81.7Confident79.6Confident117 Ų11755.9 Ų55.955%0.54728%0.275SS..Hα-helixtrans-66.9-46.3177-177.1172.7-4.700112.4A59 K60 I61 L65 K66 E67A59-Q63 WeakPolarHBondContact O-CB 3.25Å; A59-Q63 PolarHBondContact O-N 3.32Å; K60-Q63 PolarHBondContact O-N 2.83Å; I61-Q63 VanDerWaalsContact C-N 3.34Å; I61-Q63 PolarHBondContact O-N 3.48Å; Q63-L65 VanDerWaalsContact C-N 3.33Å; Q63-L65 PolarHBondContact O-N 2.97Å; Q63-K66 WeakPolarHBondContact O-CB 3.43Å; Q63-K66 PolarHBondContact O-N 3.48Å; Q63-E67 PolarHBondContact O-N 2.95Å; Q63-E67 VanDerWaalsContact O-N 3.13Å
64A82.3Confident80.3Confident14 Ų1454.6 Ų54.612%0.11627%0.273CS..Hα-helixtrans-66.2-37.3179.400000111.9F15 W19 K60 I61 K66 E67 D68F15-A64 HydrophobicContact CZ-CB 3.98Å; W19-A64 HydrophobicContact CD2-CB 4.23Å; W19-A64 VanDerWaalsContact CE2-CB 3.46Å; W19-A64 HydrophobicContact CH2-CB 3.89Å; W19-A64 HydrophobicContact CZ2-CB 3.28Å; K60-A64 WeakPolarHBondContact O-CB 3.33Å; K60-A64 PolarHBondContact O-N 3.4Å; I61-A64 PolarHBondContact O-N 3.35Å; A64-K66 VanDerWaalsContact C-N 3.34Å; A64-K66 PolarHBondContact O-N 3.2Å; A64-E67 PolarHBondContact O-N 2.81Å; A64-D68 PolarHBondContact O-N 3.29Å; A64-D68 VanDerWaalsContact O-N 3.09Å
65L81.9Confident80.9Confident0 Ų057.5 Ų57.50%029%0.285CS..Hα-helixtrans-63.5-39.1173.1-170.268.5000111.7V26 I61 Q63 E67 D68 I69 L107 F111 V135V26-L65 HydrophobicContact CG1-CD1 3.72Å; I61-L65 WeakPolarHBondContact O-CB 3.44Å; I61-L65 PolarHBondContact O-N 3.37Å; Q63-L65 VanDerWaalsContact C-N 3.33Å; Q63-L65 PolarHBondContact O-N 2.97Å; L65-E67 VanDerWaalsContact C-N 3.34Å; L65-E67 PolarHBondContact O-N 3.11Å; L65-D68 PolarHBondContact O-N 3.42Å; L65-I69 HydrophobicContact CD1-CD1 4.35Å; L65-I69 HydrophobicContact CD2-CD1 4.35Å; L65-I69 HydrophobicContact CG-CD1 3.76Å; L65-I69 HydrophobicContact CG-CG1 4.44Å; L65-I69 WeakPolarHBondContact O-CB 3.42Å; L65-I69 WeakPolarHBondContact O-CD1 3.44Å; L65-I69 WeakPolarHBondContact O-CG1 3.27Å; L65-I69 PolarHBondContact O-N 3Å; L65-L107 HydrophobicContact CD1-CD2 4.33Å; L65-F111 HydrophobicContact CD1-CE2 4.34Å; L65-F111 HydrophobicContact CD1-CZ 4.19Å; L65-V135 HydrophobicContact CD2-CB 4.26Å; L65-V135 HydrophobicContact CD2-CG1 3.63Å; L65-V135 HydrophobicContact CD2-CG2 3.66Å
66K82.3Confident81.7Confident101 Ų10149.6 Ų49.644%0.43924%0.243SC..Hα-helixtrans-59.4-43.8174.5-175.3175.1-174.1-176.50111.9H62 Q63 A64 L70 L138H62-K66 WeakPolarHBondContact O-CB 3.22Å; H62-K66 PolarHBondContact O-N 2.97Å; Q63-K66 WeakPolarHBondContact O-CB 3.43Å; Q63-K66 PolarHBondContact O-N 3.48Å; A64-K66 VanDerWaalsContact C-N 3.34Å; A64-K66 PolarHBondContact O-N 3.2Å; K66-L70 VanDerWaalsContact O-CB 3.23Å; K66-L70 WeakPolarHBondContact O-CB 3.44Å; K66-L70 PolarHBondContact O-N 2.92Å; K66-L138 HydrophobicContact CB-CD2 3.88Å; K66-L138 HydrophobicContact CD-CD1 4.11Å; K66-L138 HydrophobicContact CG-CD1 4.04Å; K66-L138 HydrophobicContact CG-CD2 4.24Å
67E84.1Confident82.1Confident113 Ų11344.6 Ų44.653%0.52822%0.222SC..Hα-helixtrans-64.8-49.5179-70.9174.6-172.500111.6Q63 A64 L65 I69 L70 D71Q63-E67 PolarHBondContact O-N 2.95Å; Q63-E67 VanDerWaalsContact O-N 3.13Å; A64-E67 PolarHBondContact O-N 2.81Å; L65-E67 VanDerWaalsContact C-N 3.34Å; L65-E67 PolarHBondContact O-N 3.11Å; E67-I69 VanDerWaalsContact C-N 3.34Å; E67-I69 PolarHBondContact O-N 3.04Å; E67-L70 PolarHBondContact O-N 2.91Å; E67-D71 PolarHBondContact O-N 3.49Å
68D84.5Confident82.6Confident8 Ų849.4 Ų49.44%0.04325%0.251CS..Hα-helixtrans-64.9-35.9179.6-75-30000112.1R23 L27 L30 A64 L65 F72R23-D68 IonicContact CZ-OD1 2.97Å; R23-D68 IonicContact NE-OD1 2.78Å; R23-D68 PolarHBondContact NE-OD1 2.87Å; R23-D68 IonicContact NE-OD2 3.29Å; R23-D68 PolarHBondContact NE-OD2 3.16Å; R23-D68 IonicContact NH2-OD1 2.96Å; R23-D68 PolarHBondContact NH2-OD1 3.15Å; L27-D68 HydrophobicContact CD2-CB 4.29Å; L30-D68 HydrophobicContact CD1-CB 4.27Å; A64-D68 PolarHBondContact O-N 3.29Å; A64-D68 VanDerWaalsContact O-N 3.09Å; L65-D68 PolarHBondContact O-N 3.42Å; D68-F72 PolarHBondContact O-N 3.36Å; D68-F72 VanDerWaalsContact O-N 3.14Å
69I84.2Confident83Confident1 Ų154 Ų541%0.00527%0.267CS..Hα-helixtrans-64.2-44.8172.8-72.8165000110.8L30 L65 E67 D71 F72 I73 L107 L138 M139L30-I69 HydrophobicContact CD2-CG1 4.26Å; L65-I69 HydrophobicContact CD1-CD1 4.35Å; L65-I69 HydrophobicContact CD2-CD1 4.35Å; L65-I69 HydrophobicContact CG-CD1 3.76Å; L65-I69 HydrophobicContact CG-CG1 4.44Å; L65-I69 WeakPolarHBondContact O-CB 3.42Å; L65-I69 WeakPolarHBondContact O-CD1 3.44Å; L65-I69 WeakPolarHBondContact O-CG1 3.27Å; L65-I69 PolarHBondContact O-N 3Å; E67-I69 VanDerWaalsContact C-N 3.34Å; E67-I69 PolarHBondContact O-N 3.04Å; I69-D71 PolarHBondContact O-N 3.48Å; I69-F72 PolarHBondContact O-N 3Å; I69-I73 HydrophobicContact CG2-CD1 3.59Å; I69-I73 HydrophobicContact CG2-CG1 4.35Å; I69-I73 VanDerWaalsContact O-CG1 3.27Å; I69-I73 WeakPolarHBondContact O-CG1 3.42Å; I69-I73 PolarHBondContact O-N 2.86Å; I69-L107 HydrophobicContact CD1-CD2 4.29Å; I69-L107 HydrophobicContact CG1-CD2 4.37Å; I69-L138 HydrophobicContact CD1-CD2 4.22Å; I69-M139 HydrophobicContact CD1-CG 3.57Å; I69-M139 HydrophobicContact CG1-CG 4.12Å; I69-M139 HydrophobicContact CG2-CG 4.12Å
70L84.3Confident83.2Confident53 Ų5351 Ų5128%0.27724%0.243SC..Hα-helixtrans-65.8-39.5-177.5-170.8151000111.5K66 E67 I73 K74 T142K66-L70 VanDerWaalsContact O-CB 3.23Å; K66-L70 WeakPolarHBondContact O-CB 3.44Å; K66-L70 PolarHBondContact O-N 2.92Å; E67-L70 PolarHBondContact O-N 2.91Å; L70-I73 PolarHBondContact O-N 3.06Å; L70-K74 HydrophobicContact CD2-CD 3.81Å; L70-K74 HydrophobicContact CD2-CG 4.31Å; L70-K74 WeakPolarHBondContact O-CG 3.5Å; L70-K74 PolarHBondContact O-N 3.09Å; L70-T142 HydrophobicContact CB-CG2 4.33Å; L70-T142 HydrophobicContact CG-CG2 4.34Å
71D84.6Confident83.4Confident80 Ų8052.1 Ų52.143%0.42825%0.251SS..Hα-helixtrans-65.7-40.8174.6-79.7-11.3000112.3E67 I69 K74 Q75E67-D71 PolarHBondContact O-N 3.49Å; I69-D71 PolarHBondContact O-N 3.48Å; D71-K74 PolarHBondContact O-N 3.34Å; D71-Q75 WeakPolarHBondContact O-CG 3.03Å; D71-Q75 PolarHBondContact O-N 3.48Å; D71-Q75 VanDerWaalsContact O-N 3.16Å
72F84.9Confident83.5Confident21 Ų2155.8 Ų55.89%0.09228%0.277CS..Hα-helixtrans-61.2-44173.5177.7-98.7000111.9L30 D68 I69 Q75 A76 F100L30-F72 HydrophobicContact CB-CD2 4.36Å; L30-F72 WeakPolarHBondContact O-CE2 3.39Å; L30-F72 VanDerWaalsContact O-CZ 3.27Å; L30-F72 WeakPolarHBondContact O-CZ 3.33Å; D68-F72 PolarHBondContact O-N 3.36Å; D68-F72 VanDerWaalsContact O-N 3.14Å; I69-F72 PolarHBondContact O-N 3Å; F72-Q75 WeakPolarHBondContact O-CB 3.37Å; F72-Q75 PolarHBondContact O-N 3.41Å; F72-A76 PolarHBondContact O-N 2.89Å; F72-F100 HydrophobicContact CE1-CD2 4.33Å
73I84.7Confident83.6Confident0 Ų057.2 Ų57.20%028%0.284CS..Hα-helixtrans-67.1-38.3179.5-68.6171.1000111.2I69 L70 Q75 A76 Q77 F100 T142 W143 I147I69-I73 HydrophobicContact CG2-CD1 3.59Å; I69-I73 HydrophobicContact CG2-CG1 4.35Å; I69-I73 VanDerWaalsContact O-CG1 3.27Å; I69-I73 WeakPolarHBondContact O-CG1 3.42Å; I69-I73 PolarHBondContact O-N 2.86Å; L70-I73 PolarHBondContact O-N 3.06Å; I73-Q75 VanDerWaalsContact C-N 3.31Å; I73-Q75 PolarHBondContact O-N 2.92Å; I73-A76 PolarHBondContact O-N 3.11Å; I73-Q77 WeakPolarHBondContact O-CB 3.34Å; I73-Q77 PolarHBondContact O-N 3.16Å; I73-F100 HydrophobicContact CD1-CE2 4.06Å; I73-F100 HydrophobicContact CG1-CE2 4.26Å; I73-T142 HydrophobicContact CD1-CG2 3.52Å; I73-W143 HydrophobicContact CD1-CB 4.37Å; I73-W143 HydrophobicContact CG1-CE3 4.15Å; I73-W143 HydrophobicContact CG2-CE3 4.43Å; I73-I147 HydrophobicContact CG2-CD1 3.97Å; I73-I147 HydrophobicContact CG2-CG1 4.15Å
74K84.8Confident83.2Confident102 Ų10260.1 Ų60.144%0.44330%0.297SS..Hα-helixtrans-60.8-38.1173-79.1175.9175.61640112.9L70 D71 Q77 T78L70-K74 HydrophobicContact CD2-CD 3.81Å; L70-K74 HydrophobicContact CD2-CG 4.31Å; L70-K74 WeakPolarHBondContact O-CG 3.5Å; L70-K74 PolarHBondContact O-N 3.09Å; D71-K74 PolarHBondContact O-N 3.34Å; K74-Q77 WeakPolarHBondContact O-CB 3.42Å; K74-Q77 PolarHBondContact O-N 2.93Å; K74-T78 PolarHBondContact O-N 2.94Å; K74-T78 PolarHBondContact O-OG1 3.14Å
75Q84.6Confident83.3Confident90 Ų9064 Ų6442%0.42132%0.316SS..Hα-helixtrans-65.6-43.5174.5-68.5175.119.200111.3D71 F72 I73 T78 R79D71-Q75 WeakPolarHBondContact O-CG 3.03Å; D71-Q75 PolarHBondContact O-N 3.48Å; D71-Q75 VanDerWaalsContact O-N 3.16Å; F72-Q75 WeakPolarHBondContact O-CB 3.37Å; F72-Q75 PolarHBondContact O-N 3.41Å; I73-Q75 VanDerWaalsContact C-N 3.31Å; I73-Q75 PolarHBondContact O-N 2.92Å; Q75-T78 PolarHBondContact O-N 3.36Å; Q75-R79 WeakPolarHBondContact O-CG 3.44Å; Q75-R79 PolarHBondContact O-N 3.5Å; Q75-R79 VanDerWaalsContact O-N 3.16Å
76A83.6Confident83.2Confident0 Ų066.2 Ų66.20%033%0.328CS..Hα-helixtrans-62.5-43.6174.400000111.8F72 I73 T78 R79 V80 W143 I147F72-A76 PolarHBondContact O-N 2.89Å; I73-A76 PolarHBondContact O-N 3.11Å; A76-T78 VanDerWaalsContact C-N 3.33Å; A76-T78 PolarHBondContact O-N 3.31Å; A76-R79 PolarHBondContact O-N 2.99Å; A76-V80 WeakPolarHBondContact O-CG2 3.47Å; A76-V80 PolarHBondContact O-N 3.08Å; A76-W143 HydrophobicContact CB-CH2 4.22Å; A76-W143 HydrophobicContact CB-CZ3 3.97Å; A76-I147 HydrophobicContact CB-CD1 4.1Å
77Q84.9Confident83Confident49 Ų4964.4 Ų64.423%0.22933%0.325CS..Hα-helixtrans-56-46.7175.8-174.5-170.932.300111.3I73 K74 R79 V80 L81 S146 I147I73-Q77 WeakPolarHBondContact O-CB 3.34Å; I73-Q77 PolarHBondContact O-N 3.16Å; K74-Q77 WeakPolarHBondContact O-CB 3.42Å; K74-Q77 PolarHBondContact O-N 2.93Å; Q77-R79 VanDerWaalsContact C-N 3.34Å; Q77-R79 PolarHBondContact O-N 3.42Å; Q77-V80 PolarHBondContact O-N 2.93Å; Q77-L81 HydrophobicContact CG-CD1 3.63Å; Q77-L81 HydrophobicContact CG-CG 4.24Å; Q77-L81 WeakPolarHBondContact O-CB 3.44Å; Q77-L81 WeakPolarHBondContact O-CG 3.43Å; Q77-L81 PolarHBondContact O-N 3.05Å; Q77-S146 PolarHBondContact NE2-O 3.2Å; Q77-I147 HydrophobicContact CB-CD1 3.98Å; Q77-I147 HydrophobicContact CB-CG1 3.71Å; Q77-I147 HydrophobicContact CG-CG1 4.01Å
78T84.6Confident83Confident100 Ų10060.5 Ų60.561%0.61331%0.313SS*.Hα-helixtrans-62.7-41179.2-52.90000111.5K74 Q75 A76 S82K74-T78 PolarHBondContact O-N 2.94Å; K74-T78 PolarHBondContact O-OG1 3.14Å; Q75-T78 PolarHBondContact O-N 3.36Å; A76-T78 VanDerWaalsContact C-N 3.33Å; A76-T78 PolarHBondContact O-N 3.31Å; T78-S82 WeakPolarHBondContact O-CB 3.39Å; T78-S82 PolarHBondContact O-N 2.8Å
79R83.7Confident83.1Confident107 Ų10760.2 Ų60.240%0.40431%0.311SS..Hα-helixtrans-63.9-45.3175.9-71.2-170.2-72.6-111.11.9111.7Q75 A76 Q77 S82 E96Q75-R79 WeakPolarHBondContact O-CG 3.44Å; Q75-R79 PolarHBondContact O-N 3.5Å; Q75-R79 VanDerWaalsContact O-N 3.16Å; A76-R79 PolarHBondContact O-N 2.99Å; Q77-R79 VanDerWaalsContact C-N 3.34Å; Q77-R79 PolarHBondContact O-N 3.42Å; R79-S82 PolarHBondContact O-OG 3.14Å; R79-E96 IonicContact CZ-OE2 3.25Å; R79-E96 VanDerWaalsContact CZ-OE2 3.25Å; R79-E96 IonicContact NE-OE1 3.8Å; R79-E96 IonicContact NE-OE2 2.95Å; R79-E96 PolarHBondContact NE-OE2 2.96Å; R79-E96 IonicContact NH2-OE2 3.69Å; R79-E96 PolarHBondContact NH2-OE2 2.82Å
80V82.9Confident83.2Confident0 Ų060.1 Ų60.10%031%0.311CS..Hα-helixtrans-66.6-50.9179.9174.80000111.2A76 Q77 S82 H83 L89 Y93 E96 I151A76-V80 WeakPolarHBondContact O-CG2 3.47Å; A76-V80 PolarHBondContact O-N 3.08Å; Q77-V80 PolarHBondContact O-N 2.93Å; V80-S82 PolarHBondContact O-N 3.4Å; V80-H83 PolarHBondContact O-N 3.45Å; V80-L89 HydrophobicContact CG1-CD1 3.66Å; V80-L89 WeakPolarHBondContact O-CD1 3.31Å; V80-Y93 HydrophobicContact CG1-CD2 4.33Å; V80-E96 HydrophobicContact CG2-CB 4.2Å; V80-E96 HydrophobicContact CG2-CG 4.13Å; V80-I151 HydrophobicContact CG1-CD1 3.92Å
81L82.2Confident83.2Confident87 Ų8763.4 Ų63.446%0.45532%0.323SS..Hα-helixtrans-72-8.7-176.7-66.7178.6000114.5Q77 H83 I151Q77-L81 HydrophobicContact CG-CD1 3.63Å; Q77-L81 HydrophobicContact CG-CG 4.24Å; Q77-L81 WeakPolarHBondContact O-CB 3.44Å; Q77-L81 WeakPolarHBondContact O-CG 3.43Å; Q77-L81 PolarHBondContact O-N 3.05Å; L81-H83 PolarHBondContact O-N 3.02Å; L81-I151 HydrophobicContact CD2-CG2 3.73Å
82S83.1Confident83.3Confident78 Ų7860.5 Ų60.555%0.54531%0.31SS..THydrogen-bonded Turntrans-66.5-20.1174.272.50000113.3T78 R79 V80T78-S82 WeakPolarHBondContact O-CB 3.39Å; T78-S82 PolarHBondContact O-N 2.8Å; R79-S82 PolarHBondContact O-OG 3.14Å; V80-S82 PolarHBondContact O-N 3.4Å
83H81.1Confident83.4Confident80 Ų8059.5 Ų59.537%0.3731%0.305SS..  trans-94.1119.2179.9-64.6-77.6000111.3V80 L81 A88 L89V80-H83 PolarHBondContact O-N 3.45Å; L81-H83 PolarHBondContact O-N 3.02Å; H83-A88 HydrophobicContact CB-CB 4.18Å; H83-L89 HydrophobicContact CB-CB 4.44Å
84Q74.3Confident83.5Confident179 Ų17959.8 Ų59.884%0.83631%0.307SS*.  trans-80.6-33.1175.7-67.7-168.9-3.800113.2R154Q84-R154 PolarHBondContact O-NH2 3.06Å
85D84.4Confident83.6Confident94 Ų9458.4 Ų58.450%0.50331%0.307SS..SBendtrans-69.3130.7178.4-178.2-91.9000111.4T87 A88 L89D85-T87 VanDerWaalsContact C-N 3.31Å; D85-T87 PolarHBondContact O-N 2.99Å; D85-T87 WeakPolarHBondContact OD1-CA 3.4Å; D85-T87 VanDerWaalsContact OD1-CB 3.25Å; D85-T87 WeakPolarHBondContact OD1-CB 3.34Å; D85-T87 PolarHBondContact OD1-N 3.34Å; D85-T87 PolarHBondContact OD1-OG1 3.36Å; D85-A88 HydrophobicContact CB-CB 3.97Å; D85-A88 PolarHBondContact O-N 2.98Å; D85-A88 PolarHBondContact OD1-N 2.75Å; D85-L89 WeakPolarHBondContact O-CB 3.19Å; D85-L89 PolarHBondContact O-N 3.42Å
86D78.8Confident83.7Confident48 Ų4854.8 Ų54.826%0.25729%0.29SS..Hα-helixtrans-58.8-38.5-176.7-80.3-14.1000113.1L90 R154 S158 K161D86-L90 WeakPolarHBondContact O-CB 3.16Å; D86-L90 PolarHBondContact O-N 2.74Å; D86-R154 IonicContact OD1-CZ 3.28Å; D86-R154 VanDerWaalsContact OD1-CZ 3.28Å; D86-R154 IonicContact OD1-NE 3Å; D86-R154 PolarHBondContact OD1-NE 3.44Å; D86-R154 IonicContact OD1-NH2 2.69Å; D86-R154 PolarHBondContact OD1-NH2 2.78Å; D86-S158 WeakPolarHBondContact CB-OG 3.06Å; D86-K161 IonicContact OD2-NZ 3.87Å
87T79.9Confident83.8Confident62 Ų6254.8 Ų54.838%0.3829%0.29SS..Hα-helixtrans-75.1-40.5179.5-1.60000112.1D85 L90 K91D85-T87 VanDerWaalsContact C-N 3.31Å; D85-T87 PolarHBondContact O-N 2.99Å; D85-T87 WeakPolarHBondContact OD1-CA 3.4Å; D85-T87 VanDerWaalsContact OD1-CB 3.25Å; D85-T87 WeakPolarHBondContact OD1-CB 3.34Å; D85-T87 PolarHBondContact OD1-N 3.34Å; D85-T87 PolarHBondContact OD1-OG1 3.36Å; T87-L90 PolarHBondContact O-N 2.94Å; T87-K91 WeakPolarHBondContact O-CG 3.45Å; T87-K91 PolarHBondContact O-N 3.03Å; T87-K91 VanDerWaalsContact O-N 3.12Å
88A83.6Confident83.8Confident32 Ų3257.6 Ų57.626%0.26430%0.298SS..Hα-helixtrans-67.2-40.1174.400000111.5H83 D85 K91 A92H83-A88 HydrophobicContact CB-CB 4.18Å; D85-A88 HydrophobicContact CB-CB 3.97Å; D85-A88 PolarHBondContact O-N 2.98Å; D85-A88 PolarHBondContact OD1-N 2.75Å; A88-K91 PolarHBondContact O-N 3.3Å; A88-A92 WeakPolarHBondContact O-CB 3.15Å; A88-A92 PolarHBondContact O-N 3.36Å
89L85.8Confident83.7Confident1 Ų156.8 Ų56.81%0.00529%0.286CS..Hα-helixtrans-57.9-47.6173.7178.570.5000111V80 H83 D85 A92 Y93 R154V80-L89 HydrophobicContact CG1-CD1 3.66Å; V80-L89 WeakPolarHBondContact O-CD1 3.31Å; H83-L89 HydrophobicContact CB-CB 4.44Å; D85-L89 WeakPolarHBondContact O-CB 3.19Å; D85-L89 PolarHBondContact O-N 3.42Å; L89-A92 PolarHBondContact O-N 3.27Å; L89-Y93 VanDerWaalsContact O-CB 3.3Å; L89-Y93 WeakPolarHBondContact O-CB 3.19Å; L89-Y93 PolarHBondContact O-N 3.29Å; L89-R154 HydrophobicContact CD2-CB 4.44Å
90L85.6Confident83.8Confident0 Ų051.7 Ų51.70%027%0.267CS..Hα-helixtrans-60.3-46.7176.9176.860.6000111.8D86 T87 Y93 I94 L155 L162 L176 V180D86-L90 WeakPolarHBondContact O-CB 3.16Å; D86-L90 PolarHBondContact O-N 2.74Å; T87-L90 PolarHBondContact O-N 2.94Å; L90-Y93 PolarHBondContact O-N 2.7Å; L90-I94 HydrophobicContact CD1-CD1 4.34Å; L90-I94 HydrophobicContact CD1-CG1 3.95Å; L90-I94 HydrophobicContact CG-CG1 4.49Å; L90-I94 WeakPolarHBondContact O-CG1 3.39Å; L90-I94 PolarHBondContact O-N 2.75Å; L90-L155 HydrophobicContact CB-CD2 4.32Å; L90-L155 HydrophobicContact CD1-CD2 3.86Å; L90-L162 HydrophobicContact CD2-CD1 3.62Å; L90-L176 HydrophobicContact CD2-CB 4.02Å; L90-L176 HydrophobicContact CG-CB 4.28Å; L90-L176 HydrophobicContact CG-CD2 4.44Å; L90-V180 HydrophobicContact CD1-CG2 3.33Å
91K85.4Confident83.8Confident122 Ų12253.6 Ų53.653%0.5328%0.276SS..Hα-helixtrans-61.4-46.6177.8-73.2174.8179.8177.90111.9T87 A88 I94 V95 L176T87-K91 WeakPolarHBondContact O-CG 3.45Å; T87-K91 PolarHBondContact O-N 3.03Å; T87-K91 VanDerWaalsContact O-N 3.12Å; A88-K91 PolarHBondContact O-N 3.3Å; K91-I94 PolarHBondContact O-N 3.38Å; K91-V95 WeakPolarHBondContact O-CG2 3.26Å; K91-V95 PolarHBondContact O-N 3.05Å; K91-V95 VanDerWaalsContact O-N 3.13Å; K91-L176 HydrophobicContact CB-CD2 4.45Å; K91-L176 HydrophobicContact CG-CD1 4.11Å; K91-L176 HydrophobicContact CG-CD2 3.81Å
92A85.8Confident83.8Confident19 Ų1952.7 Ų52.716%0.15727%0.273CS..Hα-helixtrans-62.2-43.5178.100000111.6A88 L89 I94 V95 E96A88-A92 WeakPolarHBondContact O-CB 3.15Å; A88-A92 PolarHBondContact O-N 3.36Å; L89-A92 PolarHBondContact O-N 3.27Å; A92-I94 PolarHBondContact O-N 3.06Å; A92-V95 PolarHBondContact O-N 2.96Å; A92-E96 WeakPolarHBondContact O-CG 3.31Å; A92-E96 PolarHBondContact O-N 2.8Å; A92-E96 VanDerWaalsContact O-N 3.16Å
93Y87.9Confident83.8Confident0 Ų049.3 Ų49.30%025%0.249CC..Hα-helixtrans-58.7-48.1175.6176.1-98.6000111.9V80 L89 L90 V95 E96 W97 W143 I147 F148 I151 L155 S183V80-Y93 HydrophobicContact CG1-CD2 4.33Å; L89-Y93 VanDerWaalsContact O-CB 3.3Å; L89-Y93 WeakPolarHBondContact O-CB 3.19Å; L89-Y93 PolarHBondContact O-N 3.29Å; L90-Y93 PolarHBondContact O-N 2.7Å; Y93-V95 VanDerWaalsContact C-N 3.34Å; Y93-V95 PolarHBondContact O-N 2.91Å; Y93-E96 PolarHBondContact O-N 2.92Å; Y93-W97 HydrophobicContact CD1-CB 4.46Å; Y93-W97 HydrophobicContact CE1-CB 4.08Å; Y93-W97 HydrophobicContact CE1-CG 4.29Å; Y93-W97 WeakPolarHBondContact O-CB 3.35Å; Y93-W97 PolarHBondContact O-N 2.86Å; Y93-W143 HydrophobicContact CD2-CZ2 4.28Å; Y93-W143 AromaticContact CE2-CE2 3.96Å; Y93-W143 AromaticContact CE2-CZ2 3.74Å; Y93-W143 HydrophobicContact CE2-CZ2 3.74Å; Y93-W143 AromaticContact CE2-NE1 3.59Å; Y93-W143 AromaticContact CZ-NE1 3.8Å; Y93-W143 PolarHBondContact OH-NE1 3.26Å; Y93-I147 HydrophobicContact CD2-CG2 3.96Å; Y93-I147 HydrophobicContact CE2-CG2 3.83Å; Y93-F148 AromaticContact CZ-CD2 3.98Å; Y93-F148 WeakPolarHBondContact OH-CD2 3.29Å; Y93-I151 HydrophobicContact CD2-CD1 3.69Å; Y93-I151 HydrophobicContact CE2-CD1 4.17Å; Y93-I151 HydrophobicContact CG-CD1 4.35Å; Y93-L155 HydrophobicContact CD1-CD1 3.65Å; Y93-L155 HydrophobicContact CD1-CD2 4.16Å; Y93-L155 HydrophobicContact CD2-CD1 4.03Å; Y93-L155 HydrophobicContact CE1-CD1 3.75Å; Y93-L155 HydrophobicContact CE2-CD1 4.09Å; Y93-L155 HydrophobicContact CG-CD1 3.81Å; Y93-L155 HydrophobicContact CG-CD2 4.1Å; Y93-S183 WeakPolarHBondContact CE1-OG 3.37Å; Y93-S183 WeakPolarHBondContact OH-CB 3.34Å; Y93-S183 PolarHBondContact OH-OG 3.18Å
94I86.6Confident83.7Confident6 Ų645.5 Ų45.53%0.03123%0.231CC..Hα-helixtrans-67.4-36-175.7-63.3-74.7000111.8L90 K91 A92 R98 L176 G179 V180L90-I94 HydrophobicContact CD1-CD1 4.34Å; L90-I94 HydrophobicContact CD1-CG1 3.95Å; L90-I94 HydrophobicContact CG-CG1 4.49Å; L90-I94 WeakPolarHBondContact O-CG1 3.39Å; L90-I94 PolarHBondContact O-N 2.75Å; K91-I94 PolarHBondContact O-N 3.38Å; A92-I94 PolarHBondContact O-N 3.06Å; I94-R98 WeakPolarHBondContact O-CB 3.29Å; I94-R98 VanDerWaalsContact O-CG 3.29Å; I94-R98 WeakPolarHBondContact O-CG 3.41Å; I94-R98 PolarHBondContact O-N 3.27Å; I94-L176 HydrophobicContact CB-CD2 4.25Å; I94-L176 WeakPolarHBondContact CD1-O 3.46Å; I94-L176 HydrophobicContact CG1-CD2 4.14Å; I94-L176 HydrophobicContact CG2-CD2 4.47Å; I94-G179 VanDerWaalsContact CD1-CA 3.48Å; I94-V180 HydrophobicContact CD1-CG2 4.09Å
95V86.6Confident83.8Confident73 Ų7339.7 Ų39.744%0.44221%0.206SC..Hα-helixtrans-62.1-48.3174.2170.30000110.8K91 A92 Y93 K99K91-V95 WeakPolarHBondContact O-CG2 3.26Å; K91-V95 PolarHBondContact O-N 3.05Å; K91-V95 VanDerWaalsContact O-N 3.13Å; A92-V95 PolarHBondContact O-N 2.96Å; Y93-V95 VanDerWaalsContact C-N 3.34Å; Y93-V95 PolarHBondContact O-N 2.91Å; V95-K99 WeakPolarHBondContact O-CG 3.33Å; V95-K99 PolarHBondContact O-N 3.06Å
96E86.1Confident83.6Confident13 Ų1337.4 Ų37.46%0.06119%0.193CC..Hα-helixtrans-72.2-36.5-179.8-64.5-64114.900111.9R79 V80 A92 Y93 K99 F100 W143R79-E96 IonicContact CZ-OE2 3.25Å; R79-E96 VanDerWaalsContact CZ-OE2 3.25Å; R79-E96 IonicContact NE-OE1 3.8Å; R79-E96 IonicContact NE-OE2 2.95Å; R79-E96 PolarHBondContact NE-OE2 2.96Å; R79-E96 IonicContact NH2-OE2 3.69Å; R79-E96 PolarHBondContact NH2-OE2 2.82Å; V80-E96 HydrophobicContact CG2-CB 4.2Å; V80-E96 HydrophobicContact CG2-CG 4.13Å; A92-E96 WeakPolarHBondContact O-CG 3.31Å; A92-E96 PolarHBondContact O-N 2.8Å; A92-E96 VanDerWaalsContact O-N 3.16Å; Y93-E96 PolarHBondContact O-N 2.92Å; E96-K99 PolarHBondContact O-N 2.86Å; E96-K99 IonicContact OE1-NZ 2.75Å; E96-K99 PolarHBondContact OE1-NZ 3.38Å; E96-F100 VanDerWaalsContact O-CB 3.26Å; E96-F100 WeakPolarHBondContact O-CB 3.38Å; E96-F100 PolarHBondContact O-N 3.43Å; E96-W143 HydrophobicContact CB-CH2 4.07Å
97W85.7Confident83.7Confident0 Ų035.1 Ų35.10%018%0.181CC..Hα-helixtrans-60.6-45.7174.6174.7-111.8000111.8Y93 K99 F100 F101 L140 W143 S183 N186 L187Y93-W97 HydrophobicContact CD1-CB 4.46Å; Y93-W97 HydrophobicContact CE1-CB 4.08Å; Y93-W97 HydrophobicContact CE1-CG 4.29Å; Y93-W97 WeakPolarHBondContact O-CB 3.35Å; Y93-W97 PolarHBondContact O-N 2.86Å; W97-K99 PolarHBondContact O-N 3.06Å; W97-F100 AromaticContact CE3-CD1 3.75Å; W97-F100 HydrophobicContact CE3-CD1 3.75Å; W97-F100 HydrophobicContact CE3-CE1 4.29Å; W97-F100 HydrophobicContact CH2-CD1 4.5Å; W97-F100 HydrophobicContact CH2-CE1 4.41Å; W97-F100 AromaticContact CZ3-CD1 3.61Å; W97-F100 HydrophobicContact CZ3-CD1 3.61Å; W97-F100 AromaticContact CZ3-CE1 3.68Å; W97-F100 HydrophobicContact CZ3-CE1 3.68Å; W97-F100 PolarHBondContact O-N 2.9Å; W97-F101 HydrophobicContact CH2-CD2 4.3Å; W97-F101 AromaticContact CZ2-CD2 3.84Å; W97-F101 HydrophobicContact CZ2-CD2 3.84Å; W97-F101 WeakPolarHBondContact O-CB 3.3Å; W97-F101 PolarHBondContact O-N 3.24Å; W97-L140 HydrophobicContact CH2-CD2 4.05Å; W97-W143 HydrophobicContact CB-CZ2 4.23Å; W97-W143 AromaticContact CE3-CD1 3.79Å; W97-W143 HydrophobicContact CE3-CD2 4.11Å; W97-W143 AromaticContact CE3-CE2 3.49Å; W97-W143 VanDerWaalsContact CE3-CE2 3.49Å; W97-W143 HydrophobicContact CE3-CG 4.29Å; W97-W143 AromaticContact CE3-CZ2 3.87Å; W97-W143 HydrophobicContact CE3-CZ2 3.87Å; W97-W143 AromaticContact CE3-NE1 3.24Å; W97-W143 AromaticContact CZ3-CD1 3.43Å; W97-W143 VanDerWaalsContact CZ3-CD1 3.43Å; W97-W143 HydrophobicContact CZ3-CD2 4.18Å; W97-W143 AromaticContact CZ3-CE2 3.93Å; W97-W143 AromaticContact CZ3-CG 3.91Å; W97-W143 HydrophobicContact CZ3-CG 3.91Å; W97-W143 AromaticContact CZ3-NE1 3.42Å; W97-S183 VanDerWaalsContact CE2-OG 3.27Å; W97-S183 PolarHBondContact NE1-OG 3.21Å; W97-N186 HydrophobicContact CZ2-CB 4.35Å; W97-L187 HydrophobicContact CH2-CD1 3.98Å; W97-L187 HydrophobicContact CH2-CD2 3.65Å; W97-L187 HydrophobicContact CH2-CG 3.65Å; W97-L187 HydrophobicContact CZ3-CD1 4.03Å; W97-L187 HydrophobicContact CZ3-CD2 3.79Å; W97-L187 HydrophobicContact CZ3-CG 4.08Å
98R84.8Confident83.7Confident108 Ų10832.2 Ų32.241%0.40816%0.163SC..Hα-helixtrans-61.8-45177.3-78.7169.4162.3-162.6-14.6112.2I94 F100 F101 T102I94-R98 WeakPolarHBondContact O-CB 3.29Å; I94-R98 VanDerWaalsContact O-CG 3.29Å; I94-R98 WeakPolarHBondContact O-CG 3.41Å; I94-R98 PolarHBondContact O-N 3.27Å; R98-F100 VanDerWaalsContact C-N 3.32Å; R98-F100 PolarHBondContact O-N 3Å; R98-F101 PolarHBondContact O-N 3.43Å; R98-T102 PolarHBondContact O-N 2.84Å; R98-T102 PolarHBondContact O-OG1 3.39Å; R98-T102 VanDerWaalsContact O-OG1 3.08Å
99K84.4Confident83.5Confident83 Ų8334.8 Ų34.836%0.36117%0.169SC..Hα-helixtrans-58.7-48.5176.1-69.6173.8-170.4168.50110.5Q32 V95 E96 W97 Q103Q32-K99 PolarHBondContact NE2-O 3.1Å; V95-K99 WeakPolarHBondContact O-CG 3.33Å; V95-K99 PolarHBondContact O-N 3.06Å; E96-K99 PolarHBondContact O-N 2.86Å; E96-K99 IonicContact OE1-NZ 2.75Å; E96-K99 PolarHBondContact OE1-NZ 3.38Å; W97-K99 PolarHBondContact O-N 3.06Å; K99-Q103 WeakPolarHBondContact O-CG 3.38Å; K99-Q103 PolarHBondContact O-N 2.89Å
100F85.5Confident83.1Confident0 Ų034.9 Ų34.90%017%0.169CC..Hα-helixtrans-62.4-47.7179.1171.5-99.4000112.3F72 I73 E96 W97 R98 T102 Q103 C104 M139 L140 W143F72-F100 HydrophobicContact CE1-CD2 4.33Å; I73-F100 HydrophobicContact CD1-CE2 4.06Å; I73-F100 HydrophobicContact CG1-CE2 4.26Å; E96-F100 VanDerWaalsContact O-CB 3.26Å; E96-F100 WeakPolarHBondContact O-CB 3.38Å; E96-F100 PolarHBondContact O-N 3.43Å; W97-F100 AromaticContact CE3-CD1 3.75Å; W97-F100 HydrophobicContact CE3-CD1 3.75Å; W97-F100 HydrophobicContact CE3-CE1 4.29Å; W97-F100 HydrophobicContact CH2-CD1 4.5Å; W97-F100 HydrophobicContact CH2-CE1 4.41Å; W97-F100 AromaticContact CZ3-CD1 3.61Å; W97-F100 HydrophobicContact CZ3-CD1 3.61Å; W97-F100 AromaticContact CZ3-CE1 3.68Å; W97-F100 HydrophobicContact CZ3-CE1 3.68Å; W97-F100 PolarHBondContact O-N 2.9Å; R98-F100 VanDerWaalsContact C-N 3.32Å; R98-F100 PolarHBondContact O-N 3Å; F100-T102 PolarHBondContact O-N 2.97Å; F100-Q103 CarbonylContact O-C 3.56Å; F100-Q103 WeakPolarHBondContact O-CA 3.47Å; F100-Q103 WeakPolarHBondContact O-CB 3.45Å; F100-Q103 PolarHBondContact O-N 3.24Å; F100-C104 WeakPolarHBondContact CE1-SG 3.41Å; F100-C104 WeakPolarHBondContact CZ-SG 3.49Å; F100-C104 PolarHBondContact O-N 2.91Å; F100-C104 PolarHBondContact O-SG 3.3Å; F100-C104 VanDerWaalsContact O-SG 3.42Å; F100-M139 HydrophobicContact CD2-CE 4.1Å; F100-M139 HydrophobicContact CE2-CB 4.02Å; F100-M139 HydrophobicContact CE2-CE 3.71Å; F100-M139 HydrophobicContact CZ-CB 3.8Å; F100-M139 HydrophobicContact CZ-CE 4.45Å; F100-M139 WeakPolarHBondContact CZ-O 3.18Å; F100-L140 HydrophobicContact CE1-CD2 4.21Å; F100-W143 HydrophobicContact CB-CE3 3.98Å; F100-W143 HydrophobicContact CB-CH2 4.02Å; F100-W143 HydrophobicContact CB-CZ3 3.6Å; F100-W143 AromaticContact CD1-CD2 3.77Å; F100-W143 HydrophobicContact CD1-CD2 3.77Å; F100-W143 AromaticContact CD1-CE3 3.64Å; F100-W143 HydrophobicContact CD1-CE3 3.64Å; F100-W143 HydrophobicContact CD1-CG 4.16Å; F100-W143 HydrophobicContact CD1-CZ3 4.13Å; F100-W143 HydrophobicContact CD2-CD2 4.38Å; F100-W143 AromaticContact CD2-CE3 3.48Å; F100-W143 HydrophobicContact CD2-CE3 3.48Å; F100-W143 VanDerWaalsContact CD2-CE3 3.48Å; F100-W143 AromaticContact CD2-CZ3 3.82Å; F100-W143 HydrophobicContact CD2-CZ3 3.82Å; F100-W143 HydrophobicContact CE1-CB 3.73Å; F100-W143 AromaticContact CE1-CD2 3.88Å; F100-W143 HydrophobicContact CE1-CD2 3.88Å; F100-W143 AromaticContact CE1-CE3 3.94Å; F100-W143 HydrophobicContact CE1-CE3 3.94Å; F100-W143 AromaticContact CE1-CG 3.79Å; F100-W143 HydrophobicContact CE1-CG 3.79Å; F100-W143 HydrophobicContact CE2-CB 4.3Å; F100-W143 HydrophobicContact CE2-CD2 4.46Å; F100-W143 AromaticContact CE2-CE3 3.79Å; F100-W143 HydrophobicContact CE2-CE3 3.79Å; F100-W143 HydrophobicContact CG-CD2 4.03Å; F100-W143 AromaticContact CG-CE3 3.4Å; F100-W143 HydrophobicContact CG-CE3 3.4Å; F100-W143 HydrophobicContact CG-CH2 4.31Å; F100-W143 AromaticContact CG-CZ3 3.57Å; F100-W143 HydrophobicContact CG-CZ3 3.57Å; F100-W143 HydrophobicContact CZ-CB 3.6Å; F100-W143 HydrophobicContact CZ-CD2 4.22Å; F100-W143 HydrophobicContact CZ-CE3 4Å; F100-W143 HydrophobicContact CZ-CG 4.09Å
101F82Confident82.8Confident41 Ų4134.9 Ų34.918%0.1817%0.169CC..Hα-helixtrans-62.9-40.8-178.5-170-102.6000112.2W97 R98 Q103 C104 D105 N186W97-F101 HydrophobicContact CH2-CD2 4.3Å; W97-F101 AromaticContact CZ2-CD2 3.84Å; W97-F101 HydrophobicContact CZ2-CD2 3.84Å; W97-F101 WeakPolarHBondContact O-CB 3.3Å; W97-F101 PolarHBondContact O-N 3.24Å; R98-F101 PolarHBondContact O-N 3.43Å; F101-Q103 VanDerWaalsContact C-N 3.25Å; F101-Q103 PolarHBondContact O-N 3.33Å; F101-C104 WeakPolarHBondContact O-CB 3.28Å; F101-C104 PolarHBondContact O-N 2.96Å; F101-C104 VanDerWaalsContact O-N 3.16Å; F101-D105 PolarHBondContact O-N 2.68Å; F101-N186 HydrophobicContact CE2-CB 3.91Å; F101-N186 WeakPolarHBondContact CE2-ND2 3.44Å; F101-N186 VanDerWaalsContact CZ-ND2 3.32Å; F101-N186 WeakPolarHBondContact CZ-ND2 3.45Å
102T83.3Confident82.1Confident67 Ų6731.6 Ų31.641%0.41116%0.161SC..Hα-helixtrans-60-37.2170.8-58.90000111.7R98 F100 D105 I106R98-T102 PolarHBondContact O-N 2.84Å; R98-T102 PolarHBondContact O-OG1 3.39Å; R98-T102 VanDerWaalsContact O-OG1 3.08Å; F100-T102 PolarHBondContact O-N 2.97Å; T102-D105 PolarHBondContact O-N 3.48Å; T102-I106 HydrophobicContact CG2-CD1 3.65Å; T102-I106 HydrophobicContact CG2-CG1 4.49Å; T102-I106 VanDerWaalsContact O-CG1 3.3Å; T102-I106 WeakPolarHBondContact O-CG1 3.15Å; T102-I106 PolarHBondContact O-N 3.03Å
103Q81.6Confident81.3Confident7 Ų733 Ų333%0.03317%0.165CC..Hα-helixtrans-71.2-31.2175.8-66.4-48.7-40.900113.4L29 Q32 K99 F100 F101 D105 I106 L107 M139L29-Q103 PolarHBondContact O-NE2 3.35Å; L29-Q103 PolarHBondContact O-OE1 3.35Å; Q32-Q103 HydrophobicContact CG-CG 4.06Å; Q32-Q103 VanDerWaalsContact CG-NE2 3.32Å; K99-Q103 WeakPolarHBondContact O-CG 3.38Å; K99-Q103 PolarHBondContact O-N 2.89Å; F100-Q103 CarbonylContact O-C 3.56Å; F100-Q103 WeakPolarHBondContact O-CA 3.47Å; F100-Q103 WeakPolarHBondContact O-CB 3.45Å; F100-Q103 PolarHBondContact O-N 3.24Å; F101-Q103 VanDerWaalsContact C-N 3.25Å; F101-Q103 PolarHBondContact O-N 3.33Å; Q103-D105 PolarHBondContact O-N 3.33Å; Q103-I106 PolarHBondContact O-N 2.99Å; Q103-L107 WeakPolarHBondContact O-CB 3.39Å; Q103-L107 PolarHBondContact O-N 3.13Å; Q103-M139 HydrophobicContact CB-CE 4.2Å
104C79.2Confident80.5Confident0 Ų033.1 Ų33.10%017%0.165CC..Hα-helixtrans-60.9-22.5172.2-67.30000113.5F100 F101 P108 R136F100-C104 WeakPolarHBondContact CE1-SG 3.41Å; F100-C104 WeakPolarHBondContact CZ-SG 3.49Å; F100-C104 PolarHBondContact O-N 2.91Å; F100-C104 PolarHBondContact O-SG 3.3Å; F100-C104 VanDerWaalsContact O-SG 3.42Å; F101-C104 WeakPolarHBondContact O-CB 3.28Å; F101-C104 PolarHBondContact O-N 2.96Å; F101-C104 VanDerWaalsContact O-N 3.16Å; C104-P108 WeakPolarHBondContact O-CD 3.4Å; C104-P108 WeakPolarHBondContact O-CG 3.48Å; C104-R136 HydrophobicContact CB-CG 4.22Å
105D77.6Confident79.6Confident58 Ų5833.5 Ų33.531%0.3117%0.167SC..Hα-helixtrans-96.2-22176.3-65.5-20.3000113.2F101 T102 Q103 K109 R136F101-D105 PolarHBondContact O-N 2.68Å; T102-D105 PolarHBondContact O-N 3.48Å; Q103-D105 PolarHBondContact O-N 3.33Å; D105-K109 VanDerWaalsContact O-CE 3.29Å; D105-K109 WeakPolarHBondContact O-CE 3.27Å; D105-R136 IonicContact OD1-CZ 2.78Å; D105-R136 IonicContact OD1-NE 2.69Å; D105-R136 PolarHBondContact OD1-NE 2.7Å; D105-R136 IonicContact OD1-NH2 3.62Å; D105-R136 PolarHBondContact OD1-NH2 3.41Å
106I80.4Confident78.8Confident45 Ų4534.4 Ų34.423%0.23117%0.168CC..Hα-helixtrans-93.5-46.2-177.3-65.1173000111.2L29 W40 T102 Q103 K109L29-I106 HydrophobicContact CD2-CG2 4.28Å; W40-I106 HydrophobicContact CH2-CG2 3.63Å; W40-I106 HydrophobicContact CZ2-CG2 3.75Å; T102-I106 HydrophobicContact CG2-CD1 3.65Å; T102-I106 HydrophobicContact CG2-CG1 4.49Å; T102-I106 VanDerWaalsContact O-CG1 3.3Å; T102-I106 WeakPolarHBondContact O-CG1 3.15Å; T102-I106 PolarHBondContact O-N 3.03Å; Q103-I106 PolarHBondContact O-N 2.99Å; I106-K109 WeakPolarHBondContact O-CB 3.41Å; I106-K109 WeakPolarHBondContact O-CG 3.48Å; I106-K109 PolarHBondContact O-N 2.84Å
107L80.4Confident78Confident0 Ų036.5 Ų36.50%018%0.182CC..THydrogen-bonded Turntrans-61.8-36.8-174.5-170.371000113.3V26 L29 L30 L65 I69 Q103 K109 P110 F111 V135 M139V26-L107 HydrophobicContact CG1-CD1 4.35Å; L29-L107 HydrophobicContact CB-CD1 3.99Å; L29-L107 HydrophobicContact CD1-CD1 4.32Å; L30-L107 HydrophobicContact CD2-CD2 3.66Å; L30-L107 HydrophobicContact CG-CD1 4.38Å; L30-L107 HydrophobicContact CG-CD2 4.3Å; L65-L107 HydrophobicContact CD1-CD2 4.33Å; I69-L107 HydrophobicContact CD1-CD2 4.29Å; I69-L107 HydrophobicContact CG1-CD2 4.37Å; Q103-L107 WeakPolarHBondContact O-CB 3.39Å; Q103-L107 PolarHBondContact O-N 3.13Å; L107-K109 VanDerWaalsContact C-N 3.25Å; L107-K109 PolarHBondContact O-N 2.56Å; L107-P110 WeakPolarHBondContact O-CD 3.39Å; L107-F111 HydrophobicContact CD1-CE2 4.35Å; L107-F111 WeakPolarHBondContact O-CD2 3.46Å; L107-V135 HydrophobicContact CD2-CG1 4.17Å; L107-V135 HydrophobicContact CG-CG1 4.42Å; L107-M139 HydrophobicContact CB-SD 4.19Å; L107-M139 HydrophobicContact CD2-CE 4.03Å; L107-M139 HydrophobicContact CD2-CG 4.49Å; L107-M139 HydrophobicContact CD2-SD 3.51Å; L107-M139 VanDerWaalsContact CD2-SD 3.51Å; L107-M139 HydrophobicContact CG-SD 4.46Å
108P80.1Confident77.1Confident1 Ų140 Ų401%0.00620%0.2CC..THydrogen-bonded Turntrans-65.6-22.2178.1-27.938.4000115.2C104 F111 C112 S133 V135 R136C104-P108 WeakPolarHBondContact O-CD 3.4Å; C104-P108 WeakPolarHBondContact O-CG 3.48Å; P108-F111 PolarHBondContact O-N 2.62Å; P108-C112 PolarHBondContact O-N 3.27Å; P108-S133 WeakPolarHBondContact CB-OG 3.4Å; P108-V135 HydrophobicContact CG-CB 4.47Å; P108-V135 HydrophobicContact CG-CG1 4.42Å; P108-R136 HydrophobicContact CG-CB 4.03Å
109K79.3Confident76Confident87 Ų8740.5 Ų40.538%0.37821%0.209SC..G310 helixtrans-56.9-46.8-170.8-65.1178.2177.7177.30114W40 F44 D105 I106 L107 F111 C112 M130W40-K109 HydrophobicContact CZ3-CB 4.09Å; F44-K109 WeakPolarHBondContact CE1-O 3.35Å; F44-K109 HydrophobicContact CZ-CB 4.35Å; F44-K109 WeakPolarHBondContact CZ-O 3.23Å; D105-K109 VanDerWaalsContact O-CE 3.29Å; D105-K109 WeakPolarHBondContact O-CE 3.27Å; I106-K109 WeakPolarHBondContact O-CB 3.41Å; I106-K109 WeakPolarHBondContact O-CG 3.48Å; I106-K109 PolarHBondContact O-N 2.84Å; L107-K109 VanDerWaalsContact C-N 3.25Å; L107-K109 PolarHBondContact O-N 2.56Å; K109-F111 PolarHBondContact O-N 2.71Å; K109-C112 PolarHBondContact O-SG 3.01Å; K109-M130 HydrophobicContact CD-CE 4.48Å; K109-M130 HydrophobicContact CG-CE 3.99Å; K109-M130 HydrophobicContact CG-SD 4.13Å
110P77.3Confident74.6Confident2 Ų238.5 Ų38.51%0.01321%0.212CC..G310 helixtrans-67.9-19.9175.4-15.330.9000114.3L29 W40 L43 F44 L107L29-P110 HydrophobicContact CD1-CG 4.36Å; W40-P110 HydrophobicContact CE3-CG 3.88Å; W40-P110 HydrophobicContact CH2-CG 4.22Å; W40-P110 HydrophobicContact CZ3-CG 3.38Å; L43-P110 HydrophobicContact CD2-CB 3.66Å; L43-P110 HydrophobicContact CD2-CG 3.53Å; L43-P110 HydrophobicContact CG-CB 3.76Å; L43-P110 HydrophobicContact CG-CG 4.2Å; F44-P110 VanDerWaalsContact CE1-CA 3.49Å; L107-P110 WeakPolarHBondContact O-CD 3.39Å
111F79Confident72.6Confident0 Ų048.9 Ų48.90%026%0.256CS..G310 helixtrans-100.510.2-171.8-60.5-80.2000113.8V26 V47 I61 L65 L107 P108 K109 Q113 L114 E115 V135V26-F111 HydrophobicContact CG2-CE2 4.48Å; V26-F111 HydrophobicContact CG2-CZ 3.84Å; V47-F111 HydrophobicContact CG1-CD1 3.92Å; V47-F111 HydrophobicContact CG2-CD1 3.82Å; V47-F111 HydrophobicContact CG2-CE1 3.63Å; V47-F111 HydrophobicContact CG2-CZ 4.4Å; I61-F111 HydrophobicContact CG2-CD1 4.12Å; I61-F111 HydrophobicContact CG2-CE1 3.87Å; L65-F111 HydrophobicContact CD1-CE2 4.34Å; L65-F111 HydrophobicContact CD1-CZ 4.19Å; L107-F111 HydrophobicContact CD1-CE2 4.35Å; L107-F111 WeakPolarHBondContact O-CD2 3.46Å; P108-F111 PolarHBondContact O-N 2.62Å; K109-F111 PolarHBondContact O-N 2.71Å; F111-Q113 PolarHBondContact O-N 3Å; F111-Q113 VanDerWaalsContact O-N 3.14Å; F111-L114 HydrophobicContact CB-CB 4.22Å; F111-L114 HydrophobicContact CB-CD2 4.29Å; F111-L114 HydrophobicContact CD1-CD2 4.03Å; F111-L114 WeakPolarHBondContact O-CB 3.39Å; F111-L114 PolarHBondContact O-N 2.98Å; F111-E115 PolarHBondContact O-N 3.31Å; F111-V135 HydrophobicContact CB-CG2 4.12Å
112C71.6Confident70.6Confident53 Ų5356.4 Ų56.436%0.35829%0.292SS..Hα-helixtrans-53.3-37175.1-65.30000112.9P108 K109 E115 I116P108-C112 PolarHBondContact O-N 3.27Å; K109-C112 PolarHBondContact O-SG 3.01Å; C112-E115 PolarHBondContact O-N 3.01Å; C112-I116 WeakPolarHBondContact O-CG1 3.2Å; C112-I116 PolarHBondContact O-N 2.8Å
113Q68.9Low68.7Low50 Ų5055.5 Ų55.523%0.23430%0.296CS..Hα-helixtrans-69.4-34.2178.1-170.76423.700112.6H48 C51 F111 E115 I116 T117H48-Q113 HydrophobicContact CB-CG 4.32Å; C51-Q113 HydrophobicContact CB-CG 4.26Å; F111-Q113 PolarHBondContact O-N 3Å; F111-Q113 VanDerWaalsContact O-N 3.14Å; Q113-E115 VanDerWaalsContact C-N 3.28Å; Q113-E115 PolarHBondContact O-N 3.43Å; Q113-I116 PolarHBondContact O-N 3.18Å; Q113-T117 PolarHBondContact O-N 3.17Å; Q113-T117 VanDerWaalsContact O-N 3.14Å; Q113-T117 PolarHBondContact O-OG1 2.95Å; Q113-T117 VanDerWaalsContact O-OG1 3.12Å
114L70.9Confident66.5Low1 Ų160.6 Ų60.61%0.00533%0.333CS..Hα-helixtrans-61-41.6174.7-178.773.7000110.4V47 P58 I61 F111 T117 L118V47-L114 HydrophobicContact CG1-CB 4.42Å; P58-L114 VanDerWaalsContact CA-CD1 3.47Å; P58-L114 HydrophobicContact CB-CD1 3.79Å; P58-L114 WeakPolarHBondContact O-CD1 3.49Å; I61-L114 HydrophobicContact CB-CD1 4.05Å; I61-L114 HydrophobicContact CD1-CD1 4.41Å; I61-L114 HydrophobicContact CG2-CD1 4.05Å; I61-L114 HydrophobicContact CG2-CD2 3.79Å; F111-L114 HydrophobicContact CB-CB 4.22Å; F111-L114 HydrophobicContact CB-CD2 4.29Å; F111-L114 HydrophobicContact CD1-CD2 4.03Å; F111-L114 WeakPolarHBondContact O-CB 3.39Å; F111-L114 PolarHBondContact O-N 2.98Å; L114-T117 PolarHBondContact O-N 3.08Å; L114-L118 HydrophobicContact CD1-CD1 4.07Å; L114-L118 HydrophobicContact CD1-CG 4.5Å; L114-L118 HydrophobicContact CD2-CD1 4.39Å; L114-L118 HydrophobicContact CG-CD1 3.79Å; L114-L118 WeakPolarHBondContact O-CB 3.25Å; L114-L118 VanDerWaalsContact O-CG 3.29Å; L114-L118 WeakPolarHBondContact O-CG 3.3Å; L114-L118 PolarHBondContact O-N 3.13Å
115E67.7Low64.4Low15 Ų1568.6 Ų68.67%0.0738%0.376CS..Hα-helixtrans-66.4-42.8179.7-63.1178.116900112.1F111 C112 Q113 T117 L118 M119 S133 I134F111-E115 PolarHBondContact O-N 3.31Å; C112-E115 PolarHBondContact O-N 3.01Å; Q113-E115 VanDerWaalsContact C-N 3.28Å; Q113-E115 PolarHBondContact O-N 3.43Å; E115-T117 VanDerWaalsContact C-N 3.32Å; E115-T117 PolarHBondContact O-N 2.85Å; E115-L118 PolarHBondContact O-N 3.4Å; E115-M119 WeakPolarHBondContact O-CB 3.39Å; E115-M119 VanDerWaalsContact O-CG 3.26Å; E115-M119 WeakPolarHBondContact O-CG 3.31Å; E115-M119 PolarHBondContact O-N 3.41Å; E115-M119 VanDerWaalsContact O-N 3.1Å; E115-S133 VanDerWaalsContact OE1-CA 3.24Å; E115-S133 WeakPolarHBondContact OE1-CA 3.33Å; E115-S133 WeakPolarHBondContact OE1-CB 3.34Å; E115-S133 PolarHBondContact OE1-OG 3.46Å; E115-I134 PolarHBondContact OE1-N 3.26Å
116I68.8Low62.7Low91 Ų9174.7 Ų74.747%0.46740%0.399SS..Hα-helixtrans-61.6-41.5177-65.3164.9000111C112 Q113C112-I116 WeakPolarHBondContact O-CG1 3.2Å; C112-I116 PolarHBondContact O-N 2.8Å; Q113-I116 PolarHBondContact O-N 3.18Å
117T69.2Low60.8Low58 Ų5882.3 Ų82.336%0.35643%0.431SS..Hα-helixtrans-72.5-40.1-179.8-56.10000112.5P58 Q113 L114 E115P58-T117 HydrophobicContact CB-CG2 4.49Å; P58-T117 HydrophobicContact CG-CG2 3.76Å; Q113-T117 PolarHBondContact O-N 3.17Å; Q113-T117 VanDerWaalsContact O-N 3.14Å; Q113-T117 PolarHBondContact O-OG1 2.95Å; Q113-T117 VanDerWaalsContact O-OG1 3.12Å; L114-T117 PolarHBondContact O-N 3.08Å; E115-T117 VanDerWaalsContact C-N 3.32Å; E115-T117 PolarHBondContact O-N 2.85Å
118L67.7Low59.1Low72 Ų7286.8 Ų86.838%0.37746%0.458SS..Hα-helixtrans-72.2-27.6-179.2-73.4171.9000113.5P58 H62 L114 E115 I134P58-L118 HydrophobicContact CB-CD2 3.73Å; P58-L118 HydrophobicContact CB-CG 4.03Å; H62-L118 HydrophobicContact CB-CD1 4.44Å; L114-L118 HydrophobicContact CD1-CD1 4.07Å; L114-L118 HydrophobicContact CD1-CG 4.5Å; L114-L118 HydrophobicContact CD2-CD1 4.39Å; L114-L118 HydrophobicContact CG-CD1 3.79Å; L114-L118 WeakPolarHBondContact O-CB 3.25Å; L114-L118 VanDerWaalsContact O-CG 3.29Å; L114-L118 WeakPolarHBondContact O-CG 3.3Å; L114-L118 PolarHBondContact O-N 3.13Å; E115-L118 PolarHBondContact O-N 3.4Å; L118-I134 HydrophobicContact CB-CD1 4.14Å; L118-I134 HydrophobicContact CD1-CD1 4.48Å
119M61.8Low57.6Low120 Ų12091.8 Ų91.859%0.59149%0.485SS*.Hα-helixtrans-81.8-13.1-179.7-69.8-178.474.400114.5E115 I134E115-M119 WeakPolarHBondContact O-CB 3.39Å; E115-M119 VanDerWaalsContact O-CG 3.26Å; E115-M119 WeakPolarHBondContact O-CG 3.31Å; E115-M119 PolarHBondContact O-N 3.41Å; E115-M119 VanDerWaalsContact O-N 3.1Å; M119-I134 HydrophobicContact CG-CD1 4.14Å
120G55.2Low56.2Low41 Ų4191.9 Ų91.942%0.42349%0.488SS..  trans69.2162.5179.600000115Q122G120-Q122 PolarHBondContact O-N 3.45Å
121K42.9Very low55Low217 Ų21796.9 Ų96.994%0.94351%0.511SS*.THydrogen-bonded Turntrans-63.213.7-173.8-84.1-173.3177.7179.60116.9
122Q40.1Very low53.9Low200 Ų200102.5 Ų102.594%0.93554%0.541SS*.THydrogen-bonded Turntrans-91.5-3.8174.9-75.6-155.3-0.900114.8G120G120-Q122 PolarHBondContact O-N 3.45Å
123G42.2Very low53.8Low48 Ų48100 Ų10050%0.49552%0.524SS..  trans-99.710.9-177.600000117.1N125 K126G123-N125 PolarHBondContact O-N 3.21Å; G123-K126 PolarHBondContact O-N 3.09Å
124S35.6Very low53.9Low114 Ų114100.1 Ų100.180%0.79753%0.526SS*.THydrogen-bonded Turntrans-621-162.6-170.10000117.6
125N36.6Very low54.1Low168 Ų168100.1 Ų100.190%0.89853%0.526SS*.THydrogen-bonded Turntrans-130.812.2-176.7-97-0.1000116.6G123G123-N125 PolarHBondContact O-N 3.21Å
126K42.1Very low54.7Low186 Ų186100.9 Ų100.981%0.80953%0.528SS*.SBendtrans-109.8123.6166.2-79-175.3175.9179.10109G123 T128G123-K126 PolarHBondContact O-N 3.09Å; K126-T128 PolarHBondContact O-N 3.5Å
127K40Very low55.1Low205 Ų205102 Ų10289%0.89153%0.529SS*.  trans-47.7113.2160.3-81.4177.9173.8176.40106.5N129K127-N129 PolarHBondContact O-N 3.37Å
128T43.9Very low55.5Low93 Ų93100.2 Ų100.257%0.57152%0.518SS*.  trans-61.5103174.122.60000107.3K126 M130K126-T128 PolarHBondContact O-N 3.5Å; T128-M130 PolarHBondContact O-N 3.05Å
129N48.8Very low56.1Low107 Ų10796.8 Ų96.857%0.57250%0.5SS*.  trans-65.1130.3169.4-107-4.8000106.9K127 E131 D132K127-N129 PolarHBondContact O-N 3.37Å; N129-E131 PolarHBondContact O-N 2.94Å; N129-D132 PolarHBondContact O-N 3.46Å
130M50.5Low57.1Low88 Ų8892.2 Ų92.243%0.43348%0.477SS..G310 helixtrans-59.7-10178.2-148.8151.590.100112.8K109 T128K109-M130 HydrophobicContact CD-CE 4.48Å; K109-M130 HydrophobicContact CG-CE 3.99Å; K109-M130 HydrophobicContact CG-SD 4.13Å; T128-M130 PolarHBondContact O-N 3.05Å
131E51Low58.2Low108 Ų10892.4 Ų92.451%0.50547%0.469SS..G310 helixtrans-71.8-25.2172.4-63.4-156.4145.300115.3N129N129-E131 PolarHBondContact O-N 2.94Å
132D56.1Low60Low117 Ų11782.4 Ų82.463%0.62643%0.426SS*.G310 helixtrans-100.418.3-178.7-65.7-27.8000112.4N129 I134 K194N129-D132 PolarHBondContact O-N 3.46Å; D132-I134 PolarHBondContact O-N 2.78Å; D132-K194 IonicContact OD1-NZ 3.84Å
133S68.8Low62.1Low1 Ų172.9 Ų72.91%0.00738%0.382CS..  trans-58.2129.3177.4161.30000111.7P108 E115 V135 R136 K137P108-S133 WeakPolarHBondContact CB-OG 3.4Å; E115-S133 VanDerWaalsContact OE1-CA 3.24Å; E115-S133 WeakPolarHBondContact OE1-CA 3.33Å; E115-S133 WeakPolarHBondContact OE1-CB 3.34Å; E115-S133 PolarHBondContact OE1-OG 3.46Å; S133-V135 VanDerWaalsContact C-N 3.26Å; S133-V135 PolarHBondContact O-N 3.23Å; S133-V135 PolarHBondContact OG-N 3.44Å; S133-R136 PolarHBondContact O-N 2.81Å; S133-R136 PolarHBondContact OG-N 2.93Å; S133-K137 WeakPolarHBondContact O-CB 3.16Å; S133-K137 PolarHBondContact O-N 3.1Å
134I72.7Confident64.1Low52 Ų5272.3 Ų72.327%0.26737%0.367SS..Hα-helixtrans-61.6-39.6176.2-64.2169.9000110.1E115 L118 M119 D132 K137 L138E115-I134 PolarHBondContact OE1-N 3.26Å; L118-I134 HydrophobicContact CB-CD1 4.14Å; L118-I134 HydrophobicContact CD1-CD1 4.48Å; M119-I134 HydrophobicContact CG-CD1 4.14Å; D132-I134 PolarHBondContact O-N 2.78Å; I134-K137 PolarHBondContact O-N 3.33Å; I134-L138 WeakPolarHBondContact O-CB 3.36Å; I134-L138 PolarHBondContact O-N 2.89Å
135V75.4Confident66.2Low1 Ų173.6 Ų73.61%0.00636%0.361CS..Hα-helixtrans-66.9-44.3178.4177.10000110.9L65 L107 P108 F111 S133 K137 L138 M139L65-V135 HydrophobicContact CD2-CB 4.26Å; L65-V135 HydrophobicContact CD2-CG1 3.63Å; L65-V135 HydrophobicContact CD2-CG2 3.66Å; L107-V135 HydrophobicContact CD2-CG1 4.17Å; L107-V135 HydrophobicContact CG-CG1 4.42Å; P108-V135 HydrophobicContact CG-CB 4.47Å; P108-V135 HydrophobicContact CG-CG1 4.42Å; F111-V135 HydrophobicContact CB-CG2 4.12Å; S133-V135 VanDerWaalsContact C-N 3.26Å; S133-V135 PolarHBondContact O-N 3.23Å; S133-V135 PolarHBondContact OG-N 3.44Å; V135-K137 VanDerWaalsContact C-N 3.35Å; V135-K137 PolarHBondContact O-N 3.29Å; V135-L138 PolarHBondContact O-N 2.86Å; V135-M139 WeakPolarHBondContact O-CG 3.42Å; V135-M139 PolarHBondContact O-N 3.29Å
136R79.2Confident68.3Low32 Ų3266.8 Ų66.812%0.12133%0.326CS..Hα-helixtrans-61.5-44.3176.7-168.1176-168.2-154.76.2111.3C104 D105 P108 S133 M139 L140C104-R136 HydrophobicContact CB-CG 4.22Å; D105-R136 IonicContact OD1-CZ 2.78Å; D105-R136 IonicContact OD1-NE 2.69Å; D105-R136 PolarHBondContact OD1-NE 2.7Å; D105-R136 IonicContact OD1-NH2 3.62Å; D105-R136 PolarHBondContact OD1-NH2 3.41Å; P108-R136 HydrophobicContact CG-CB 4.03Å; S133-R136 PolarHBondContact O-N 2.81Å; S133-R136 PolarHBondContact OG-N 2.93Å; R136-M139 PolarHBondContact O-N 2.9Å; R136-L140 HydrophobicContact CG-CD1 4.1Å; R136-L140 WeakPolarHBondContact O-CG 3.42Å; R136-L140 PolarHBondContact O-N 3.48Å
137K76.9Confident70.1Confident114 Ų11458.1 Ų58.150%0.49629%0.288SS..Hα-helixtrans-61.3-46.7176.4-173.7173.5-177.3176.10111.7S133 I134 V135 M139 L140 D141S133-K137 WeakPolarHBondContact O-CB 3.16Å; S133-K137 PolarHBondContact O-N 3.1Å; I134-K137 PolarHBondContact O-N 3.33Å; V135-K137 VanDerWaalsContact C-N 3.35Å; V135-K137 PolarHBondContact O-N 3.29Å; K137-M139 VanDerWaalsContact C-N 3.33Å; K137-M139 PolarHBondContact O-N 3.45Å; K137-L140 PolarHBondContact O-N 3.47Å; K137-D141 WeakPolarHBondContact CG-OD2 3.33Å; K137-D141 WeakPolarHBondContact O-CB 3.27Å; K137-D141 PolarHBondContact O-N 2.74Å
138L78.4Confident72.1Confident21 Ų2148.5 Ų48.511%0.1125%0.247CC..Hα-helixtrans-58.3-43.8176.7179.366000112.3K66 I69 I134 V135 T142K66-L138 HydrophobicContact CB-CD2 3.88Å; K66-L138 HydrophobicContact CD-CD1 4.11Å; K66-L138 HydrophobicContact CG-CD1 4.04Å; K66-L138 HydrophobicContact CG-CD2 4.24Å; I69-L138 HydrophobicContact CD1-CD2 4.22Å; I134-L138 WeakPolarHBondContact O-CB 3.36Å; I134-L138 PolarHBondContact O-N 2.89Å; V135-L138 PolarHBondContact O-N 2.86Å; L138-T142 WeakPolarHBondContact O-CB 3.34Å; L138-T142 PolarHBondContact O-N 3.48Å; L138-T142 PolarHBondContact O-OG1 2.89Å
139M80.4Confident73.9Confident0 Ų046.3 Ų46.30%024%0.235CC..Hα-helixtrans-60.2-52175.8-72.3-176.782.500111L30 I69 F100 Q103 L107 V135 R136 K137 T142 W143L30-M139 HydrophobicContact CD2-CE 4.02Å; I69-M139 HydrophobicContact CD1-CG 3.57Å; I69-M139 HydrophobicContact CG1-CG 4.12Å; I69-M139 HydrophobicContact CG2-CG 4.12Å; F100-M139 HydrophobicContact CD2-CE 4.1Å; F100-M139 HydrophobicContact CE2-CB 4.02Å; F100-M139 HydrophobicContact CE2-CE 3.71Å; F100-M139 HydrophobicContact CZ-CB 3.8Å; F100-M139 HydrophobicContact CZ-CE 4.45Å; F100-M139 WeakPolarHBondContact CZ-O 3.18Å; Q103-M139 HydrophobicContact CB-CE 4.2Å; L107-M139 HydrophobicContact CB-SD 4.19Å; L107-M139 HydrophobicContact CD2-CE 4.03Å; L107-M139 HydrophobicContact CD2-CG 4.49Å; L107-M139 HydrophobicContact CD2-SD 3.51Å; L107-M139 VanDerWaalsContact CD2-SD 3.51Å; L107-M139 HydrophobicContact CG-SD 4.46Å; V135-M139 WeakPolarHBondContact O-CG 3.42Å; V135-M139 PolarHBondContact O-N 3.29Å; R136-M139 PolarHBondContact O-N 2.9Å; K137-M139 VanDerWaalsContact C-N 3.33Å; K137-M139 PolarHBondContact O-N 3.45Å; M139-T142 PolarHBondContact O-N 3.36Å; M139-W143 PolarHBondContact O-N 3.26Å
140L81.4Confident75.4Confident23 Ų2346.4 Ų46.412%0.1224%0.235CC..Hα-helixtrans-62.7-44.1-177.5-69167.4000112W97 F100 R136 K137 W143 N144 L187W97-L140 HydrophobicContact CH2-CD2 4.05Å; F100-L140 HydrophobicContact CE1-CD2 4.21Å; R136-L140 HydrophobicContact CG-CD1 4.1Å; R136-L140 WeakPolarHBondContact O-CG 3.42Å; R136-L140 PolarHBondContact O-N 3.48Å; K137-L140 PolarHBondContact O-N 3.47Å; L140-W143 PolarHBondContact O-N 3.33Å; L140-N144 WeakPolarHBondContact O-CB 3.41Å; L140-N144 PolarHBondContact O-N 2.93Å; L140-L187 HydrophobicContact CB-CD2 4.18Å; L140-L187 HydrophobicContact CD2-CD2 3.84Å; L140-L187 WeakPolarHBondContact O-CD2 3.32Å
141D80Confident77Confident45 Ų4542.5 Ų42.524%0.24122%0.216CC..Hα-helixtrans-63-43.3177.3-71.7-23.7000110.9K137 W143 N144 E145 S189K137-D141 WeakPolarHBondContact CG-OD2 3.33Å; K137-D141 WeakPolarHBondContact O-CB 3.27Å; K137-D141 PolarHBondContact O-N 2.74Å; D141-W143 VanDerWaalsContact C-N 3.35Å; D141-W143 PolarHBondContact O-N 3.26Å; D141-N144 WeakPolarHBondContact O-CB 3.45Å; D141-N144 PolarHBondContact O-N 3.48Å; D141-E145 WeakPolarHBondContact O-CG 3.39Å; D141-E145 PolarHBondContact O-N 3.37Å; D141-S189 PolarHBondContact OD1-OG 3.37Å
142T80.9Confident78.5Confident8 Ų841.6 Ų41.65%0.04921%0.211CC..Hα-helixtrans-66.2-36.6178.4-50.20000112L70 I73 L138 M139 S146L70-T142 HydrophobicContact CB-CG2 4.33Å; L70-T142 HydrophobicContact CG-CG2 4.34Å; I73-T142 HydrophobicContact CD1-CG2 3.52Å; L138-T142 WeakPolarHBondContact O-CB 3.34Å; L138-T142 PolarHBondContact O-N 3.48Å; L138-T142 PolarHBondContact O-OG1 2.89Å; M139-T142 PolarHBondContact O-N 3.36Å; T142-S146 VanDerWaalsContact O-CB 3.27Å; T142-S146 WeakPolarHBondContact O-CB 3.41Å; T142-S146 PolarHBondContact O-N 2.88Å; T142-S146 PolarHBondContact O-OG 3.02Å
143W83.8Confident79.9Confident0 Ų039.2 Ų39.20%020%0.203CC..Hα-helixtrans-67.5-40.4174.7-175.3-83.2000111.7I73 A76 Y93 E96 W97 F100 M139 L140 D141 I147 F148 L187I73-W143 HydrophobicContact CD1-CB 4.37Å; I73-W143 HydrophobicContact CG1-CE3 4.15Å; I73-W143 HydrophobicContact CG2-CE3 4.43Å; A76-W143 HydrophobicContact CB-CH2 4.22Å; A76-W143 HydrophobicContact CB-CZ3 3.97Å; Y93-W143 HydrophobicContact CD2-CZ2 4.28Å; Y93-W143 AromaticContact CE2-CE2 3.96Å; Y93-W143 AromaticContact CE2-CZ2 3.74Å; Y93-W143 HydrophobicContact CE2-CZ2 3.74Å; Y93-W143 AromaticContact CE2-NE1 3.59Å; Y93-W143 AromaticContact CZ-NE1 3.8Å; Y93-W143 PolarHBondContact OH-NE1 3.26Å; E96-W143 HydrophobicContact CB-CH2 4.07Å; W97-W143 HydrophobicContact CB-CZ2 4.23Å; W97-W143 AromaticContact CE3-CD1 3.79Å; W97-W143 HydrophobicContact CE3-CD2 4.11Å; W97-W143 AromaticContact CE3-CE2 3.49Å; W97-W143 VanDerWaalsContact CE3-CE2 3.49Å; W97-W143 HydrophobicContact CE3-CG 4.29Å; W97-W143 AromaticContact CE3-CZ2 3.87Å; W97-W143 HydrophobicContact CE3-CZ2 3.87Å; W97-W143 AromaticContact CE3-NE1 3.24Å; W97-W143 AromaticContact CZ3-CD1 3.43Å; W97-W143 VanDerWaalsContact CZ3-CD1 3.43Å; W97-W143 HydrophobicContact CZ3-CD2 4.18Å; W97-W143 AromaticContact CZ3-CE2 3.93Å; W97-W143 AromaticContact CZ3-CG 3.91Å; W97-W143 HydrophobicContact CZ3-CG 3.91Å; W97-W143 AromaticContact CZ3-NE1 3.42Å; F100-W143 HydrophobicContact CB-CE3 3.98Å; F100-W143 HydrophobicContact CB-CH2 4.02Å; F100-W143 HydrophobicContact CB-CZ3 3.6Å; F100-W143 AromaticContact CD1-CD2 3.77Å; F100-W143 HydrophobicContact CD1-CD2 3.77Å; F100-W143 AromaticContact CD1-CE3 3.64Å; F100-W143 HydrophobicContact CD1-CE3 3.64Å; F100-W143 HydrophobicContact CD1-CG 4.16Å; F100-W143 HydrophobicContact CD1-CZ3 4.13Å; F100-W143 HydrophobicContact CD2-CD2 4.38Å; F100-W143 AromaticContact CD2-CE3 3.48Å; F100-W143 HydrophobicContact CD2-CE3 3.48Å; F100-W143 VanDerWaalsContact CD2-CE3 3.48Å; F100-W143 AromaticContact CD2-CZ3 3.82Å; F100-W143 HydrophobicContact CD2-CZ3 3.82Å; F100-W143 HydrophobicContact CE1-CB 3.73Å; F100-W143 AromaticContact CE1-CD2 3.88Å; F100-W143 HydrophobicContact CE1-CD2 3.88Å; F100-W143 AromaticContact CE1-CE3 3.94Å; F100-W143 HydrophobicContact CE1-CE3 3.94Å; F100-W143 AromaticContact CE1-CG 3.79Å; F100-W143 HydrophobicContact CE1-CG 3.79Å; F100-W143 HydrophobicContact CE2-CB 4.3Å; F100-W143 HydrophobicContact CE2-CD2 4.46Å; F100-W143 AromaticContact CE2-CE3 3.79Å; F100-W143 HydrophobicContact CE2-CE3 3.79Å; F100-W143 HydrophobicContact CG-CD2 4.03Å; F100-W143 AromaticContact CG-CE3 3.4Å; F100-W143 HydrophobicContact CG-CE3 3.4Å; F100-W143 HydrophobicContact CG-CH2 4.31Å; F100-W143 AromaticContact CG-CZ3 3.57Å; F100-W143 HydrophobicContact CG-CZ3 3.57Å; F100-W143 HydrophobicContact CZ-CB 3.6Å; F100-W143 HydrophobicContact CZ-CD2 4.22Å; F100-W143 HydrophobicContact CZ-CE3 4Å; F100-W143 HydrophobicContact CZ-CG 4.09Å; M139-W143 PolarHBondContact O-N 3.26Å; L140-W143 PolarHBondContact O-N 3.33Å; D141-W143 VanDerWaalsContact C-N 3.35Å; D141-W143 PolarHBondContact O-N 3.26Å; W143-I147 HydrophobicContact CD2-CD1 4.06Å; W143-I147 HydrophobicContact CE3-CD1 3.91Å; W143-I147 HydrophobicContact CH2-CD1 3.77Å; W143-I147 HydrophobicContact CZ2-CD1 3.92Å; W143-I147 HydrophobicContact CZ2-CG2 4.5Å; W143-I147 HydrophobicContact CZ3-CD1 3.76Å; W143-I147 PolarHBondContact O-N 3.45Å; W143-F148 PolarHBondContact O-N 2.78Å; W143-F148 VanDerWaalsContact O-N 3.16Å; W143-L187 HydrophobicContact CB-CD2 4.31Å; W143-L187 HydrophobicContact CG-CD2 4.42Å
144N82.6Confident80.7Confident36 Ų3643.5 Ų43.519%0.19322%0.219CC..Iπ-helixtrans-61.7-50.5177.2-17125.5000111.5L140 D141 F148 S149 L187L140-N144 WeakPolarHBondContact O-CB 3.41Å; L140-N144 PolarHBondContact O-N 2.93Å; D141-N144 WeakPolarHBondContact O-CB 3.45Å; D141-N144 PolarHBondContact O-N 3.48Å; N144-F148 WeakPolarHBondContact OD1-CD1 3.41Å; N144-S149 WeakPolarHBondContact O-CB 3.47Å; N144-S149 PolarHBondContact O-N 3.47Å; N144-S149 PolarHBondContact O-OG 2.83Å; N144-L187 HydrophobicContact CB-CB 4.45Å; N144-L187 HydrophobicContact CB-CD2 4.3Å
145E81.1Confident81.3Confident141 Ų14141 Ų4166%0.65921%0.207SC*.Iπ-helixtrans-64.2-44.1179.5-71.7179.9179.800112.6D141 S149D141-E145 WeakPolarHBondContact O-CG 3.39Å; D141-E145 PolarHBondContact O-N 3.37Å; E145-S149 PolarHBondContact O-OG 2.9Å; E145-S149 VanDerWaalsContact O-OG 3.1Å
146S79.3Confident81.8Confident24 Ų2442.5 Ų42.517%0.16821%0.213CC..Iπ-helixtrans-81.8-43.6-171.2-570000113.2Q77 T142 N150Q77-S146 PolarHBondContact NE2-O 3.2Å; T142-S146 VanDerWaalsContact O-CB 3.27Å; T142-S146 WeakPolarHBondContact O-CB 3.41Å; T142-S146 PolarHBondContact O-N 2.88Å; T142-S146 PolarHBondContact O-OG 3.02Å; S146-N150 PolarHBondContact O-ND2 3.05Å
147I81.4Confident82.2Confident4 Ų445.1 Ų45.12%0.02123%0.23CC..Iπ-helixtrans-111.8-66.1-170.4-58.9178.3000109.9I73 A76 Q77 Y93 W143 S149 N150 I151I73-I147 HydrophobicContact CG2-CD1 3.97Å; I73-I147 HydrophobicContact CG2-CG1 4.15Å; A76-I147 HydrophobicContact CB-CD1 4.1Å; Q77-I147 HydrophobicContact CB-CD1 3.98Å; Q77-I147 HydrophobicContact CB-CG1 3.71Å; Q77-I147 HydrophobicContact CG-CG1 4.01Å; Y93-I147 HydrophobicContact CD2-CG2 3.96Å; Y93-I147 HydrophobicContact CE2-CG2 3.83Å; W143-I147 HydrophobicContact CD2-CD1 4.06Å; W143-I147 HydrophobicContact CE3-CD1 3.91Å; W143-I147 HydrophobicContact CH2-CD1 3.77Å; W143-I147 HydrophobicContact CZ2-CD1 3.92Å; W143-I147 HydrophobicContact CZ2-CG2 4.5Å; W143-I147 HydrophobicContact CZ3-CD1 3.76Å; W143-I147 PolarHBondContact O-N 3.45Å; I147-S149 PolarHBondContact O-N 3.14Å; I147-N150 PolarHBondContact O-N 3.07Å; I147-I151 HydrophobicContact CG2-CD1 3.64Å; I147-I151 HydrophobicContact CG2-CG1 4.38Å; I147-I151 WeakPolarHBondContact O-CG1 3.29Å; I147-I151 PolarHBondContact O-N 3.21Å
148F82.2Confident82.7Confident4 Ų440 Ų402%0.01821%0.208CC..Iπ-helixtrans-63.6-45.9-162.9-174.2-107.8000113.1Y93 W143 N144 N150 I151 K152 L155 Y184 L187Y93-F148 AromaticContact CZ-CD2 3.98Å; Y93-F148 WeakPolarHBondContact OH-CD2 3.29Å; W143-F148 PolarHBondContact O-N 2.78Å; W143-F148 VanDerWaalsContact O-N 3.16Å; N144-F148 WeakPolarHBondContact OD1-CD1 3.41Å; F148-N150 PolarHBondContact O-N 3.25Å; F148-N150 VanDerWaalsContact O-N 3.11Å; F148-I151 PolarHBondContact O-N 2.89Å; F148-I151 VanDerWaalsContact O-N 3.12Å; F148-K152 HydrophobicContact CD1-CB 4.35Å; F148-K152 HydrophobicContact CE1-CB 4.17Å; F148-K152 HydrophobicContact CE2-CB 4.47Å; F148-K152 HydrophobicContact CZ-CB 4.23Å; F148-K152 WeakPolarHBondContact O-CA 3.31Å; F148-K152 WeakPolarHBondContact O-CB 3.36Å; F148-K152 PolarHBondContact O-N 2.98Å; F148-L155 HydrophobicContact CD2-CD1 4.3Å; F148-L155 HydrophobicContact CE2-CD1 4.45Å; F148-Y184 HydrophobicContact CE1-CD1 4.11Å; F148-Y184 HydrophobicContact CE1-CE1 4.05Å; F148-Y184 HydrophobicContact CE1-CG 4.48Å; F148-Y184 HydrophobicContact CE2-CD2 4.3Å; F148-Y184 HydrophobicContact CE2-CE2 4.16Å; F148-Y184 AromaticContact CZ-CD1 3.72Å; F148-Y184 HydrophobicContact CZ-CD1 3.72Å; F148-Y184 AromaticContact CZ-CD2 3.71Å; F148-Y184 HydrophobicContact CZ-CD2 3.71Å; F148-Y184 AromaticContact CZ-CE1 3.69Å; F148-Y184 HydrophobicContact CZ-CE1 3.69Å; F148-Y184 AromaticContact CZ-CE2 3.68Å; F148-Y184 HydrophobicContact CZ-CE2 3.68Å; F148-Y184 AromaticContact CZ-CG 3.71Å; F148-Y184 HydrophobicContact CZ-CG 3.71Å; F148-Y184 AromaticContact CZ-CZ 3.66Å; F148-L187 HydrophobicContact CB-CD1 3.66Å; F148-L187 HydrophobicContact CD1-CD1 3.59Å; F148-L187 HydrophobicContact CD2-CD1 3.79Å; F148-L187 HydrophobicContact CE1-CD1 4.1Å; F148-L187 HydrophobicContact CE2-CD1 4.28Å; F148-L187 HydrophobicContact CG-CD1 3.4Å; F148-L187 VanDerWaalsContact CG-CD1 3.4Å; F148-L187 HydrophobicContact CZ-CD1 4.4Å
149S80.9Confident83.1Confident46 Ų4639 Ų3932%0.32220%0.203SC..Hα-helixtrans-55.9-32.7-178.4640000113.8N144 E145 I147N144-S149 WeakPolarHBondContact O-CB 3.47Å; N144-S149 PolarHBondContact O-N 3.47Å; N144-S149 PolarHBondContact O-OG 2.83Å; E145-S149 PolarHBondContact O-OG 2.9Å; E145-S149 VanDerWaalsContact O-OG 3.1Å; I147-S149 PolarHBondContact O-N 3.14Å
150N81.1Confident83.6Confident109 Ų10939.8 Ų39.858%0.58321%0.207SC*.Hα-helixtrans-82.9-27.4-177.7-66.1-40.5000113.4S146 I147 F148S146-N150 PolarHBondContact O-ND2 3.05Å; I147-N150 PolarHBondContact O-N 3.07Å; F148-N150 PolarHBondContact O-N 3.25Å; F148-N150 VanDerWaalsContact O-N 3.11Å
151I84.3Confident83.9Confident6 Ų644.8 Ų44.83%0.03123%0.228CC..Hα-helixtrans-115.7-2.2-175.167.6178.3000113.9V80 L81 Y93 I147 F148 S153 R154 L155V80-I151 HydrophobicContact CG1-CD1 3.92Å; L81-I151 HydrophobicContact CD2-CG2 3.73Å; Y93-I151 HydrophobicContact CD2-CD1 3.69Å; Y93-I151 HydrophobicContact CE2-CD1 4.17Å; Y93-I151 HydrophobicContact CG-CD1 4.35Å; I147-I151 HydrophobicContact CG2-CD1 3.64Å; I147-I151 HydrophobicContact CG2-CG1 4.38Å; I147-I151 WeakPolarHBondContact O-CG1 3.29Å; I147-I151 PolarHBondContact O-N 3.21Å; F148-I151 PolarHBondContact O-N 2.89Å; F148-I151 VanDerWaalsContact O-N 3.12Å; I151-S153 VanDerWaalsContact C-N 3.3Å; I151-S153 PolarHBondContact O-N 3.08Å; I151-R154 PolarHBondContact O-N 2.98Å; I151-R154 VanDerWaalsContact O-N 3.15Å; I151-L155 HydrophobicContact CB-CG 4.43Å; I151-L155 HydrophobicContact CD1-CD1 3.74Å; I151-L155 HydrophobicContact CD1-CD2 4.44Å; I151-L155 HydrophobicContact CD1-CG 4.14Å; I151-L155 HydrophobicContact CG1-CD1 3.66Å; I151-L155 HydrophobicContact CG1-CG 3.99Å; I151-L155 WeakPolarHBondContact O-CG 3.21Å; I151-L155 PolarHBondContact O-N 3.04Å
152K82.4Confident84.3Confident89 Ų8943.9 Ų43.939%0.38722%0.223SC..Hα-helixtrans-53-40.4-173.964179.6179.8176.80114.1F148 Q156 Y184F148-K152 HydrophobicContact CD1-CB 4.35Å; F148-K152 HydrophobicContact CE1-CB 4.17Å; F148-K152 HydrophobicContact CE2-CB 4.47Å; F148-K152 HydrophobicContact CZ-CB 4.23Å; F148-K152 WeakPolarHBondContact O-CA 3.31Å; F148-K152 WeakPolarHBondContact O-CB 3.36Å; F148-K152 PolarHBondContact O-N 2.98Å; K152-Q156 VanDerWaalsContact O-CB 3.25Å; K152-Q156 WeakPolarHBondContact O-CB 3.26Å; K152-Q156 PolarHBondContact O-N 3.14Å; K152-Y184 WeakPolarHBondContact CB-OH 3.46Å; K152-Y184 PolarHBondContact O-OH 3.17Å
153S84Confident84.6Confident67 Ų6743.5 Ų43.547%0.46922%0.221SC..Hα-helixtrans-67.9-47.8179.452.20000111.5I151 L155 Q156 D157I151-S153 VanDerWaalsContact C-N 3.3Å; I151-S153 PolarHBondContact O-N 3.08Å; S153-L155 VanDerWaalsContact C-N 3.34Å; S153-L155 PolarHBondContact O-N 3.42Å; S153-Q156 WeakPolarHBondContact O-CB 3.4Å; S153-Q156 PolarHBondContact O-N 3.19Å; S153-D157 PolarHBondContact O-N 3.42Å
154R85.3Confident84.9Confident91 Ų9147.3 Ų47.334%0.34324%0.238SC..Hα-helixtrans-62.1-40.9177-66.5-177.865.5-1701112.1Q84 D86 L89 I151 S158Q84-R154 PolarHBondContact O-NH2 3.06Å; D86-R154 IonicContact OD1-CZ 3.28Å; D86-R154 VanDerWaalsContact OD1-CZ 3.28Å; D86-R154 IonicContact OD1-NE 3Å; D86-R154 PolarHBondContact OD1-NE 3.44Å; D86-R154 IonicContact OD1-NH2 2.69Å; D86-R154 PolarHBondContact OD1-NH2 2.78Å; L89-R154 HydrophobicContact CD2-CB 4.44Å; I151-R154 PolarHBondContact O-N 2.98Å; I151-R154 VanDerWaalsContact O-N 3.15Å; R154-S158 VanDerWaalsContact O-CB 3.31Å; R154-S158 WeakPolarHBondContact O-CB 3.22Å; R154-S158 PolarHBondContact O-N 3.08Å; R154-S158 PolarHBondContact O-OG 3.19Å
155L85.4Confident85.1Confident1 Ų146.4 Ų46.41%0.00524%0.235CC..Hα-helixtrans-64.5-43.1175.6-68.8-179.9000111.6L90 Y93 F148 I151 S153 S158 A159 V180L90-L155 HydrophobicContact CB-CD2 4.32Å; L90-L155 HydrophobicContact CD1-CD2 3.86Å; Y93-L155 HydrophobicContact CD1-CD1 3.65Å; Y93-L155 HydrophobicContact CD1-CD2 4.16Å; Y93-L155 HydrophobicContact CD2-CD1 4.03Å; Y93-L155 HydrophobicContact CE1-CD1 3.75Å; Y93-L155 HydrophobicContact CE2-CD1 4.09Å; Y93-L155 HydrophobicContact CG-CD1 3.81Å; Y93-L155 HydrophobicContact CG-CD2 4.1Å; F148-L155 HydrophobicContact CD2-CD1 4.3Å; F148-L155 HydrophobicContact CE2-CD1 4.45Å; I151-L155 HydrophobicContact CB-CG 4.43Å; I151-L155 HydrophobicContact CD1-CD1 3.74Å; I151-L155 HydrophobicContact CD1-CD2 4.44Å; I151-L155 HydrophobicContact CD1-CG 4.14Å; I151-L155 HydrophobicContact CG1-CD1 3.66Å; I151-L155 HydrophobicContact CG1-CG 3.99Å; I151-L155 WeakPolarHBondContact O-CG 3.21Å; I151-L155 PolarHBondContact O-N 3.04Å; S153-L155 VanDerWaalsContact C-N 3.34Å; S153-L155 PolarHBondContact O-N 3.42Å; L155-S158 PolarHBondContact O-N 3.26Å; L155-A159 WeakPolarHBondContact O-CB 3.27Å; L155-A159 PolarHBondContact O-N 2.94Å; L155-V180 HydrophobicContact CB-CG2 4.41Å
156Q87.3Confident85.4Confident31 Ų3141.6 Ų41.615%0.14521%0.213CC..Hα-helixtrans-62.6-50.1177.1-176.1-177.3-61.800111.2K152 S153 S158 A159 M160 Y184 A205K152-Q156 VanDerWaalsContact O-CB 3.25Å; K152-Q156 WeakPolarHBondContact O-CB 3.26Å; K152-Q156 PolarHBondContact O-N 3.14Å; S153-Q156 WeakPolarHBondContact O-CB 3.4Å; S153-Q156 PolarHBondContact O-N 3.19Å; Q156-S158 VanDerWaalsContact C-N 3.29Å; Q156-S158 PolarHBondContact O-N 3.25Å; Q156-A159 WeakPolarHBondContact O-CB 3.49Å; Q156-A159 PolarHBondContact O-N 3.16Å; Q156-A159 VanDerWaalsContact O-N 3.16Å; Q156-M160 HydrophobicContact CG-CE 4.25Å; Q156-M160 WeakPolarHBondContact O-CG 3.5Å; Q156-M160 PolarHBondContact O-N 3.34Å; Q156-Y184 HydrophobicContact CB-CE2 4.48Å; Q156-Y184 PolarHBondContact OE1-OH 3.49Å; Q156-A205 HydrophobicContact CG-CB 4.03Å
157D86.6Confident85.8Confident88 Ų8841 Ų4147%0.47121%0.207SC..Hα-helixtrans-61-40179.4-70.3-19.4000111.7S153 M160 K161S153-D157 PolarHBondContact O-N 3.42Å; D157-M160 PolarHBondContact O-N 2.84Å; D157-K161 WeakPolarHBondContact O-CG 3.29Å; D157-K161 PolarHBondContact O-N 2.71Å
158S87.1Confident86.1Confident6 Ų646.2 Ų46.24%0.04223%0.234CC..Hα-helixtrans-64.6-43.1175.5-57.40000111.9D86 R154 L155 Q156 K161 L162D86-S158 WeakPolarHBondContact CB-OG 3.06Å; R154-S158 VanDerWaalsContact O-CB 3.31Å; R154-S158 WeakPolarHBondContact O-CB 3.22Å; R154-S158 PolarHBondContact O-N 3.08Å; R154-S158 PolarHBondContact O-OG 3.19Å; L155-S158 PolarHBondContact O-N 3.26Å; Q156-S158 VanDerWaalsContact C-N 3.29Å; Q156-S158 PolarHBondContact O-N 3.25Å; S158-K161 PolarHBondContact O-N 3.47Å; S158-L162 WeakPolarHBondContact O-CG 3.46Å; S158-L162 PolarHBondContact O-N 2.98Å; S158-L162 VanDerWaalsContact O-N 3.09Å
159A87.6Confident86.2Confident0 Ų049.1 Ų49.10%027%0.266CS..Hα-helixtrans-62.6-42175.100000111.6L155 Q156 L162 V163 V177 V180 F202L155-A159 WeakPolarHBondContact O-CB 3.27Å; L155-A159 PolarHBondContact O-N 2.94Å; Q156-A159 WeakPolarHBondContact O-CB 3.49Å; Q156-A159 PolarHBondContact O-N 3.16Å; Q156-A159 VanDerWaalsContact O-N 3.16Å; A159-L162 PolarHBondContact O-N 3.49Å; A159-V163 WeakPolarHBondContact O-CG2 3.4Å; A159-V163 PolarHBondContact O-N 2.85Å; A159-V177 HydrophobicContact CB-CG2 4.28Å; A159-V180 HydrophobicContact CB-CB 4.47Å; A159-V180 HydrophobicContact CB-CG1 4.39Å; A159-V180 HydrophobicContact CB-CG2 4.41Å; A159-F202 HydrophobicContact CB-CE2 4.45Å
160M90.5Very high86.5Confident16 Ų1653 Ų538%0.07928%0.279CS..Hα-helixtrans-67.1-35.8177.3-63.3-50.215000112.6Q156 D157 V163 H164 F202 A205 Y206Q156-M160 HydrophobicContact CG-CE 4.25Å; Q156-M160 WeakPolarHBondContact O-CG 3.5Å; Q156-M160 PolarHBondContact O-N 3.34Å; D157-M160 PolarHBondContact O-N 2.84Å; M160-V163 PolarHBondContact O-N 3.44Å; M160-H164 WeakPolarHBondContact O-CB 3.37Å; M160-H164 PolarHBondContact O-N 3.32Å; M160-F202 HydrophobicContact CE-CD2 3.93Å; M160-F202 HydrophobicContact CE-CE2 3.75Å; M160-F202 HydrophobicContact CE-CG 4.41Å; M160-F202 HydrophobicContact CE-CZ 4.09Å; M160-A205 HydrophobicContact CE-CB 4.17Å; M160-Y206 HydrophobicContact CE-CD2 4.14Å; M160-Y206 HydrophobicContact SD-CD2 4.03Å; M160-Y206 HydrophobicContact SD-CG 4.4Å
161K88.4Confident86.6Confident129 Ų12953 Ų5356%0.56129%0.294SS*.Hα-helixtrans-62.5-41.5172.5-74.9172.5-174.4172.30111.9D86 D157 S158 H164 A165D86-K161 IonicContact OD2-NZ 3.87Å; D157-K161 WeakPolarHBondContact O-CG 3.29Å; D157-K161 PolarHBondContact O-N 2.71Å; S158-K161 PolarHBondContact O-N 3.47Å; K161-H164 WeakPolarHBondContact O-CB 3.39Å; K161-H164 PolarHBondContact O-N 3.18Å; K161-A165 PolarHBondContact O-N 3.13Å
162L87.9Confident86.7Confident25 Ų2554.5 Ų54.513%0.13130%0.3CS..Hα-helixtrans-63.6-45.1175.8-69.7176.1000111.6L90 S158 A159 H164 A165 E166 F172 L176 V177L90-L162 HydrophobicContact CD2-CD1 3.62Å; S158-L162 WeakPolarHBondContact O-CG 3.46Å; S158-L162 PolarHBondContact O-N 2.98Å; S158-L162 VanDerWaalsContact O-N 3.09Å; A159-L162 PolarHBondContact O-N 3.49Å; L162-H164 VanDerWaalsContact C-N 3.29Å; L162-H164 PolarHBondContact O-N 2.99Å; L162-A165 PolarHBondContact O-N 3.47Å; L162-E166 PolarHBondContact O-N 3.23Å; L162-F172 VanDerWaalsContact C-CE1 3.46Å; L162-F172 HydrophobicContact CB-CD1 4.1Å; L162-F172 HydrophobicContact CB-CD2 4.01Å; L162-F172 HydrophobicContact CB-CE1 3.95Å; L162-F172 HydrophobicContact CB-CE2 3.92Å; L162-F172 HydrophobicContact CB-CG 4.14Å; L162-F172 HydrophobicContact CB-CZ 3.89Å; L162-F172 HydrophobicContact CD1-CD2 4.03Å; L162-F172 HydrophobicContact CD1-CE2 4.26Å; L162-F172 HydrophobicContact CD2-CB 4.19Å; L162-F172 HydrophobicContact CD2-CD2 4.33Å; L162-F172 HydrophobicContact CD2-CG 4.15Å; L162-F172 HydrophobicContact CG-CD2 4.37Å; L162-F172 WeakPolarHBondContact O-CD1 3.42Å; L162-F172 WeakPolarHBondContact O-CE1 3.33Å; L162-L176 HydrophobicContact CD1-CB 3.99Å; L162-L176 HydrophobicContact CD1-CD1 3.91Å; L162-V177 HydrophobicContact CB-CG2 4.31Å; L162-V177 HydrophobicContact CD1-CG2 4.5Å
163V88.4Confident86.8Confident1 Ų154.6 Ų54.61%0.00631%0.305CS..Hα-helixtrans-60.4-40.4175.51730000111.2A159 M160 E166 R167 V177 Y206 Y248A159-V163 WeakPolarHBondContact O-CG2 3.4Å; A159-V163 PolarHBondContact O-N 2.85Å; M160-V163 PolarHBondContact O-N 3.44Å; V163-E166 PolarHBondContact O-N 3.29Å; V163-R167 WeakPolarHBondContact O-CG 3.4Å; V163-R167 PolarHBondContact O-N 3.33Å; V163-R167 VanDerWaalsContact O-N 3.14Å; V163-V177 HydrophobicContact CG2-CG1 4.13Å; V163-V177 HydrophobicContact CG2-CG2 4.03Å; V163-Y206 HydrophobicContact CG1-CE2 3.91Å; V163-Y206 HydrophobicContact CG2-CE2 3.9Å; V163-Y248 HydrophobicContact CG2-CD2 4.26Å; V163-Y248 HydrophobicContact CG2-CE2 4.41Å
164H88.5Confident86.8Confident79 Ų7951.6 Ų51.637%0.36628%0.284SS..Hα-helixtrans-62.7-43.4174.6-177.588.6000112.4M160 K161 L162 R167 L168 F213M160-H164 WeakPolarHBondContact O-CB 3.37Å; M160-H164 PolarHBondContact O-N 3.32Å; K161-H164 WeakPolarHBondContact O-CB 3.39Å; K161-H164 PolarHBondContact O-N 3.18Å; L162-H164 VanDerWaalsContact C-N 3.29Å; L162-H164 PolarHBondContact O-N 2.99Å; H164-R167 WeakPolarHBondContact O-CB 3.35Å; H164-R167 PolarHBondContact O-N 3.04Å; H164-L168 PolarHBondContact O-N 3.28Å; H164-F213 AromaticContact CE1-CD2 3.45Å; H164-F213 VanDerWaalsContact CE1-CD2 3.45Å; H164-F213 WeakPolarHBondContact CE1-CD2 3.47Å; H164-F213 AromaticContact CE1-CE2 3.77Å; H164-F213 AromaticContact ND1-CD2 3.46Å; H164-F213 WeakPolarHBondContact ND1-CD2 3.25Å; H164-F213 AromaticContact ND1-CE2 3.98Å
165A87.6Confident86.8Confident17 Ų1750.6 Ų50.614%0.1428%0.283CS..Hα-helixtrans-63.3-40.1177.200000112.4K161 L162 R167 L168 G169 E170K161-A165 PolarHBondContact O-N 3.13Å; L162-A165 PolarHBondContact O-N 3.47Å; A165-R167 VanDerWaalsContact C-N 3.31Å; A165-R167 PolarHBondContact O-N 2.98Å; A165-L168 CarbonylContact O-C 3.52Å; A165-L168 WeakPolarHBondContact O-CA 3.48Å; A165-L168 WeakPolarHBondContact O-CB 3.45Å; A165-L168 PolarHBondContact O-N 3.3Å; A165-G169 PolarHBondContact O-N 3.45Å; A165-E170 HydrophobicContact CB-CB 4.14Å; A165-E170 WeakPolarHBondContact O-CB 3.26Å; A165-E170 PolarHBondContact O-N 3.5Å
166E88.3Confident86.8Confident40 Ų4051.1 Ų51.119%0.18729%0.286CS..Hα-helixtrans-66.9-31175-177.6-167.3-132.500112.8L162 V163 L168 G169 E170 F172 R244 R247 Y248L162-E166 PolarHBondContact O-N 3.23Å; V163-E166 PolarHBondContact O-N 3.29Å; E166-L168 PolarHBondContact O-N 2.87Å; E166-G169 PolarHBondContact O-N 3.4Å; E166-E170 VanDerWaalsContact CA-O 3.26Å; E166-E170 WeakPolarHBondContact CA-O 3.46Å; E166-F172 HydrophobicContact CB-CD1 3.81Å; E166-F172 HydrophobicContact CB-CE1 3.44Å; E166-F172 VanDerWaalsContact CB-CE1 3.44Å; E166-F172 HydrophobicContact CG-CE1 4.19Å; E166-R244 IonicContact OE2-CZ 3.21Å; E166-R244 IonicContact OE2-NE 3.51Å; E166-R244 PolarHBondContact OE2-NE 3.44Å; E166-R244 IonicContact OE2-NH2 3.55Å; E166-R247 IonicContact OE1-NH1 3.96Å; E166-Y248 PolarHBondContact OE1-OH 2.91Å; E166-Y248 VanDerWaalsContact OE1-OH 3.14Å; E166-Y248 WeakPolarHBondContact OE2-CE2 3.3Å; E166-Y248 PolarHBondContact OE2-OH 2.94Å
167R86.6Confident86.8Confident13 Ų1349.6 Ų49.65%0.04928%0.279CS..Hα-helixtrans-64-28.3171.2-71.5172.6172.31429.9113V163 H164 A165 G169 T210 F213 E241V163-R167 WeakPolarHBondContact O-CG 3.4Å; V163-R167 PolarHBondContact O-N 3.33Å; V163-R167 VanDerWaalsContact O-N 3.14Å; H164-R167 WeakPolarHBondContact O-CB 3.35Å; H164-R167 PolarHBondContact O-N 3.04Å; A165-R167 VanDerWaalsContact C-N 3.31Å; A165-R167 PolarHBondContact O-N 2.98Å; R167-G169 VanDerWaalsContact C-N 3.3Å; R167-T210 PolarHBondContact NH1-OG1 3.22Å; R167-T210 VanDerWaalsContact NH2-CG2 3.34Å; R167-T210 PolarHBondContact NH2-OG1 3.42Å; R167-F213 HydrophobicContact CB-CE1 3.9Å; R167-F213 HydrophobicContact CB-CE2 4.11Å; R167-F213 HydrophobicContact CB-CZ 3.65Å; R167-F213 HydrophobicContact CG-CE1 4.36Å; R167-E241 IonicContact CZ-OE1 2.62Å; R167-E241 IonicContact CZ-OE2 3.78Å; R167-E241 IonicContact NE-OE1 2.8Å; R167-E241 PolarHBondContact NE-OE1 3.33Å; R167-E241 IonicContact NE-OE2 3.73Å; R167-E241 IonicContact NH2-OE1 3.12Å; R167-E241 PolarHBondContact NH2-OE1 2.95Å; R167-E241 IonicContact NH2-OE2 3.55Å; R167-E241 PolarHBondContact NH2-OE2 3.04Å
168L87.1Confident86.7Confident112 Ų11246.3 Ų46.359%0.58626%0.261SS*.THydrogen-bonded Turntrans-83.4-5.9173.3-63.2172.5000112.8H164 A165 E166 F213H164-L168 PolarHBondContact O-N 3.28Å; A165-L168 CarbonylContact O-C 3.52Å; A165-L168 WeakPolarHBondContact O-CA 3.48Å; A165-L168 WeakPolarHBondContact O-CB 3.45Å; A165-L168 PolarHBondContact O-N 3.3Å; E166-L168 PolarHBondContact O-N 2.87Å; L168-F213 HydrophobicContact CD2-CE2 4.18Å; L168-F213 HydrophobicContact CD2-CZ 4.4Å
169G84.7Confident86.5Confident66 Ų6646 Ų4668%0.6826%0.259SS*.THydrogen-bonded Turntrans103.26.2176.500000115.2A165 E166 R167A165-G169 PolarHBondContact O-N 3.45Å; E166-G169 PolarHBondContact O-N 3.4Å; R167-G169 VanDerWaalsContact C-N 3.3Å
170E87.3Confident86.4Confident127 Ų12746 Ų4659%0.59326%0.259SS*.  trans-80.7128.6177.7-62.8-172.117600111.9A165 E166A165-E170 HydrophobicContact CB-CB 4.14Å; A165-E170 WeakPolarHBondContact O-CB 3.26Å; A165-E170 PolarHBondContact O-N 3.5Å; E166-E170 VanDerWaalsContact CA-O 3.26Å; E166-E170 WeakPolarHBondContact CA-O 3.46Å
171A83.1Confident86.1Confident108 Ų10846.7 Ų46.789%0.89326%0.261SS*.  trans-82.8130177.200000111.1
172F86.6Confident85.9Confident39 Ų3943.1 Ų43.117%0.17125%0.246CC..  trans-135.5164.6174.174.7-94.9000111.8L162 E166 S174 V177 Y248L162-F172 VanDerWaalsContact C-CE1 3.46Å; L162-F172 HydrophobicContact CB-CD1 4.1Å; L162-F172 HydrophobicContact CB-CD2 4.01Å; L162-F172 HydrophobicContact CB-CE1 3.95Å; L162-F172 HydrophobicContact CB-CE2 3.92Å; L162-F172 HydrophobicContact CB-CG 4.14Å; L162-F172 HydrophobicContact CB-CZ 3.89Å; L162-F172 HydrophobicContact CD1-CD2 4.03Å; L162-F172 HydrophobicContact CD1-CE2 4.26Å; L162-F172 HydrophobicContact CD2-CB 4.19Å; L162-F172 HydrophobicContact CD2-CD2 4.33Å; L162-F172 HydrophobicContact CD2-CG 4.15Å; L162-F172 HydrophobicContact CG-CD2 4.37Å; L162-F172 WeakPolarHBondContact O-CD1 3.42Å; L162-F172 WeakPolarHBondContact O-CE1 3.33Å; E166-F172 HydrophobicContact CB-CD1 3.81Å; E166-F172 HydrophobicContact CB-CE1 3.44Å; E166-F172 VanDerWaalsContact CB-CE1 3.44Å; E166-F172 HydrophobicContact CG-CE1 4.19Å; F172-S174 PolarHBondContact O-N 3.28Å; F172-V177 HydrophobicContact CE2-CB 4.45Å; F172-V177 HydrophobicContact CE2-CG2 3.58Å; F172-V177 HydrophobicContact CZ-CG2 3.74Å; F172-Y248 HydrophobicContact CZ-CE2 4.24Å; F172-Y248 AromaticContact CZ-CZ 3.81Å; F172-Y248 VanDerWaalsContact CZ-OH 3.31Å; F172-Y248 WeakPolarHBondContact CZ-OH 3.45Å
173D84.6Confident85.6Confident90 Ų9042 Ų4248%0.48124%0.24SC..  trans-69.7105.4175.2-176.88.7000111Q175 L176D173-Q175 PolarHBondContact O-N 2.94Å; D173-Q175 VanDerWaalsContact OD1-CB 3.3Å; D173-Q175 WeakPolarHBondContact OD1-CB 3.16Å; D173-Q175 WeakPolarHBondContact OD1-CG 3.44Å; D173-Q175 PolarHBondContact OD1-N 3.27Å; D173-L176 HydrophobicContact CB-CD1 4.36Å; D173-L176 HydrophobicContact CB-CG 4.28Å; D173-L176 WeakPolarHBondContact O-CB 3.31Å; D173-L176 WeakPolarHBondContact O-CG 3.49Å; D173-L176 PolarHBondContact O-N 2.86Å
174S84.6Confident85.2Confident5 Ų542 Ų424%0.03524%0.24CC..THydrogen-bonded Turntrans-59.7-19.6-178.9-69.70000114.4F172 L176 V177 I178 R247 Y248F172-S174 PolarHBondContact O-N 3.28Å; S174-L176 PolarHBondContact O-N 2.92Å; S174-V177 PolarHBondContact O-N 3.4Å; S174-I178 WeakPolarHBondContact O-CD1 3.3Å; S174-I178 VanDerWaalsContact O-CG1 3.25Å; S174-I178 WeakPolarHBondContact O-CG1 3.46Å; S174-I178 PolarHBondContact O-N 3.02Å; S174-I178 VanDerWaalsContact O-N 3.1Å; S174-R247 VanDerWaalsContact CB-NH2 3.29Å; S174-R247 PolarHBondContact OG-NE 3.49Å; S174-R247 PolarHBondContact OG-NH1 2.87Å; S174-R247 PolarHBondContact OG-NH2 2.94Å; S174-Y248 PolarHBondContact OG-OH 3.2Å
175Q84.8Confident84.8Confident70 Ų7038.5 Ų38.533%0.32722%0.224SC..Hα-helixtrans-66-21.9175.6-65.1-62.2-29.900113.3D173 G179D173-Q175 PolarHBondContact O-N 2.94Å; D173-Q175 VanDerWaalsContact OD1-CB 3.3Å; D173-Q175 WeakPolarHBondContact OD1-CB 3.16Å; D173-Q175 WeakPolarHBondContact OD1-CG 3.44Å; D173-Q175 PolarHBondContact OD1-N 3.27Å; Q175-G179 PolarHBondContact O-N 3.41Å
176L85.9Confident84.3Confident11 Ų1139.4 Ų39.46%0.05823%0.226CC..Hα-helixtrans-66.8-43.8176.1-60.4176.6000111.5L90 K91 I94 L162 D173 S174 V180L90-L176 HydrophobicContact CD2-CB 4.02Å; L90-L176 HydrophobicContact CG-CB 4.28Å; L90-L176 HydrophobicContact CG-CD2 4.44Å; K91-L176 HydrophobicContact CB-CD2 4.45Å; K91-L176 HydrophobicContact CG-CD1 4.11Å; K91-L176 HydrophobicContact CG-CD2 3.81Å; I94-L176 HydrophobicContact CB-CD2 4.25Å; I94-L176 WeakPolarHBondContact CD1-O 3.46Å; I94-L176 HydrophobicContact CG1-CD2 4.14Å; I94-L176 HydrophobicContact CG2-CD2 4.47Å; L162-L176 HydrophobicContact CD1-CB 3.99Å; L162-L176 HydrophobicContact CD1-CD1 3.91Å; D173-L176 HydrophobicContact CB-CD1 4.36Å; D173-L176 HydrophobicContact CB-CG 4.28Å; D173-L176 WeakPolarHBondContact O-CB 3.31Å; D173-L176 WeakPolarHBondContact O-CG 3.49Å; D173-L176 PolarHBondContact O-N 2.86Å; S174-L176 PolarHBondContact O-N 2.92Å; L176-V180 WeakPolarHBondContact O-CG2 3.4Å; L176-V180 PolarHBondContact O-N 3.35Å
177V86.1Confident83.6Confident0 Ų037.7 Ų37.70%022%0.219CC..Hα-helixtrans-75.6-41.3177.8177.40000110.6A159 L162 V163 F172 S174 G179 V180 R181 F202 Y248A159-V177 HydrophobicContact CB-CG2 4.28Å; L162-V177 HydrophobicContact CB-CG2 4.31Å; L162-V177 HydrophobicContact CD1-CG2 4.5Å; V163-V177 HydrophobicContact CG2-CG1 4.13Å; V163-V177 HydrophobicContact CG2-CG2 4.03Å; F172-V177 HydrophobicContact CE2-CB 4.45Å; F172-V177 HydrophobicContact CE2-CG2 3.58Å; F172-V177 HydrophobicContact CZ-CG2 3.74Å; S174-V177 PolarHBondContact O-N 3.4Å; V177-G179 PolarHBondContact O-N 3.25Å; V177-V180 PolarHBondContact O-N 3.19Å; V177-R181 PolarHBondContact O-N 3Å; V177-F202 HydrophobicContact CG1-CZ 4.05Å; V177-Y248 HydrophobicContact CB-CD1 3.99Å; V177-Y248 HydrophobicContact CB-CE1 4.14Å; V177-Y248 HydrophobicContact CB-CG 4.44Å; V177-Y248 HydrophobicContact CG1-CD1 3.8Å; V177-Y248 HydrophobicContact CG1-CD2 4.34Å; V177-Y248 HydrophobicContact CG1-CE1 4.39Å; V177-Y248 HydrophobicContact CG1-CG 3.81Å
178I85.3Confident82.7Confident19 Ų1937.9 Ų37.910%0.09722%0.222CC..Hα-helixtrans-59.8-44.8177.1-67.9167.4000111.2S174 V180 R181 E182 Y248S174-I178 WeakPolarHBondContact O-CD1 3.3Å; S174-I178 VanDerWaalsContact O-CG1 3.25Å; S174-I178 WeakPolarHBondContact O-CG1 3.46Å; S174-I178 PolarHBondContact O-N 3.02Å; S174-I178 VanDerWaalsContact O-N 3.1Å; I178-V180 PolarHBondContact O-N 2.94Å; I178-R181 WeakPolarHBondContact O-CB 3.36Å; I178-R181 PolarHBondContact O-N 3.43Å; I178-E182 HydrophobicContact CG2-CG 4.39Å; I178-E182 WeakPolarHBondContact CG2-OE1 3.16Å; I178-E182 WeakPolarHBondContact O-CG 3.35Å; I178-E182 PolarHBondContact O-N 3.49Å; I178-Y248 HydrophobicContact CG1-CD1 4.08Å; I178-Y248 HydrophobicContact CG1-CE1 4.47Å
179G82.6Confident81.3Confident0 Ų035 Ų350%021%0.211CC..Hα-helixtrans-71.1-28.5-179.300000113.5I94 Q175 V177 S183I94-G179 VanDerWaalsContact CD1-CA 3.48Å; Q175-G179 PolarHBondContact O-N 3.41Å; V177-G179 PolarHBondContact O-N 3.25Å; G179-S183 PolarHBondContact O-N 3.49Å; G179-S183 PolarHBondContact O-OG 3.38Å
180V84.8Confident80.2Confident0 Ų034.1 Ų34.10%019%0.191CC..Hα-helixtrans-67-47.4169.4174.60000110.1L90 I94 L155 A159 L176 V177 I178 E182 S183 Y184 F202L90-V180 HydrophobicContact CD1-CG2 3.33Å; I94-V180 HydrophobicContact CD1-CG2 4.09Å; L155-V180 HydrophobicContact CB-CG2 4.41Å; A159-V180 HydrophobicContact CB-CB 4.47Å; A159-V180 HydrophobicContact CB-CG1 4.39Å; A159-V180 HydrophobicContact CB-CG2 4.41Å; L176-V180 WeakPolarHBondContact O-CG2 3.4Å; L176-V180 PolarHBondContact O-N 3.35Å; V177-V180 PolarHBondContact O-N 3.19Å; I178-V180 PolarHBondContact O-N 2.94Å; V180-E182 PolarHBondContact O-N 3.46Å; V180-S183 WeakPolarHBondContact O-CB 3.35Å; V180-S183 PolarHBondContact O-N 2.69Å; V180-S183 VanDerWaalsContact O-N 3.13Å; V180-Y184 HydrophobicContact CG1-CD2 3.74Å; V180-Y184 HydrophobicContact CG1-CE2 3.65Å; V180-Y184 VanDerWaalsContact O-CD2 3.31Å; V180-Y184 WeakPolarHBondContact O-CD2 3.34Å; V180-Y184 PolarHBondContact O-N 2.8Å; V180-F202 HydrophobicContact CB-CE2 4.41Å; V180-F202 HydrophobicContact CG1-CD2 4.01Å; V180-F202 HydrophobicContact CG1-CE2 3.84Å
181R85.6Confident78.9Confident29 Ų2933.4 Ų33.411%0.10920%0.197CC..Hα-helixtrans-54.3-50.8173.8179.3-151.363.3-171.2-1.6111.3V177 I178 S183 Y184 V185 Y198 F202 Y248 L249V177-R181 PolarHBondContact O-N 3Å; I178-R181 WeakPolarHBondContact O-CB 3.36Å; I178-R181 PolarHBondContact O-N 3.43Å; R181-S183 PolarHBondContact O-N 3.33Å; R181-Y184 PolarHBondContact O-N 2.83Å; R181-Y184 VanDerWaalsContact O-N 3.08Å; R181-V185 HydrophobicContact CG-CG2 4.41Å; R181-V185 WeakPolarHBondContact O-CG2 3.5Å; R181-V185 PolarHBondContact O-N 2.84Å; R181-Y198 HydrophobicContact CG-CD2 4.3Å; R181-Y198 HydrophobicContact CG-CE2 3.83Å; R181-F202 HydrophobicContact CB-CE1 4.08Å; R181-F202 HydrophobicContact CB-CZ 4.12Å; R181-F202 HydrophobicContact CG-CE1 4.3Å; R181-Y248 VanDerWaalsContact CD-O 3.22Å; R181-Y248 WeakPolarHBondContact CD-O 3.38Å; R181-L249 PolarHBondContact NH1-O 3.34Å
182E83Confident77.7Confident55 Ų5537.1 Ų37.126%0.25720%0.196SC..Hα-helixtrans-59.9-35.3178.9-75.4173.1178.400112.4I178 V180 V185 N186I178-E182 HydrophobicContact CG2-CG 4.39Å; I178-E182 WeakPolarHBondContact CG2-OE1 3.16Å; I178-E182 WeakPolarHBondContact O-CG 3.35Å; I178-E182 PolarHBondContact O-N 3.49Å; V180-E182 PolarHBondContact O-N 3.46Å; E182-V185 PolarHBondContact O-N 3.3Å; E182-N186 VanDerWaalsContact O-CB 3.23Å; E182-N186 WeakPolarHBondContact O-CB 3.41Å; E182-N186 VanDerWaalsContact O-CG 3.27Å; E182-N186 PolarHBondContact O-N 3.43Å; E182-N186 PolarHBondContact O-ND2 3.33Å
183S82.3Confident76.8Confident0 Ų037.3 Ų37.30%020%0.199CC..Hα-helixtrans-63-48.7172.4-57.50000111.2Y93 W97 G179 V180 R181 V185 L187Y93-S183 WeakPolarHBondContact CE1-OG 3.37Å; Y93-S183 WeakPolarHBondContact OH-CB 3.34Å; Y93-S183 PolarHBondContact OH-OG 3.18Å; W97-S183 VanDerWaalsContact CE2-OG 3.27Å; W97-S183 PolarHBondContact NE1-OG 3.21Å; G179-S183 PolarHBondContact O-N 3.49Å; G179-S183 PolarHBondContact O-OG 3.38Å; V180-S183 WeakPolarHBondContact O-CB 3.35Å; V180-S183 PolarHBondContact O-N 2.69Å; V180-S183 VanDerWaalsContact O-N 3.13Å; R181-S183 PolarHBondContact O-N 3.33Å; S183-V185 VanDerWaalsContact C-N 3.3Å; S183-V185 PolarHBondContact O-N 3.5Å; S183-L187 WeakPolarHBondContact O-CB 3.13Å; S183-L187 WeakPolarHBondContact O-CD1 3.31Å; S183-L187 WeakPolarHBondContact O-CG 3.3Å; S183-L187 PolarHBondContact O-N 3.02Å
184Y80.6Confident75.9Confident2 Ų237.8 Ų37.81%0.00820%0.197CC..Hα-helixtrans-62-33.9178.3-86.4-77.1000113.7F148 K152 Q156 V180 R181 I197 N201 F202F148-Y184 HydrophobicContact CE1-CD1 4.11Å; F148-Y184 HydrophobicContact CE1-CE1 4.05Å; F148-Y184 HydrophobicContact CE1-CG 4.48Å; F148-Y184 HydrophobicContact CE2-CD2 4.3Å; F148-Y184 HydrophobicContact CE2-CE2 4.16Å; F148-Y184 AromaticContact CZ-CD1 3.72Å; F148-Y184 HydrophobicContact CZ-CD1 3.72Å; F148-Y184 AromaticContact CZ-CD2 3.71Å; F148-Y184 HydrophobicContact CZ-CD2 3.71Å; F148-Y184 AromaticContact CZ-CE1 3.69Å; F148-Y184 HydrophobicContact CZ-CE1 3.69Å; F148-Y184 AromaticContact CZ-CE2 3.68Å; F148-Y184 HydrophobicContact CZ-CE2 3.68Å; F148-Y184 AromaticContact CZ-CG 3.71Å; F148-Y184 HydrophobicContact CZ-CG 3.71Å; F148-Y184 AromaticContact CZ-CZ 3.66Å; K152-Y184 WeakPolarHBondContact CB-OH 3.46Å; K152-Y184 PolarHBondContact O-OH 3.17Å; Q156-Y184 HydrophobicContact CB-CE2 4.48Å; Q156-Y184 PolarHBondContact OE1-OH 3.49Å; V180-Y184 HydrophobicContact CG1-CD2 3.74Å; V180-Y184 HydrophobicContact CG1-CE2 3.65Å; V180-Y184 VanDerWaalsContact O-CD2 3.31Å; V180-Y184 WeakPolarHBondContact O-CD2 3.34Å; V180-Y184 PolarHBondContact O-N 2.8Å; R181-Y184 PolarHBondContact O-N 2.83Å; R181-Y184 VanDerWaalsContact O-N 3.08Å; Y184-I197 HydrophobicContact CD1-CG2 4.14Å; Y184-N201 HydrophobicContact CD1-CB 4.33Å; Y184-N201 HydrophobicContact CE1-CB 3.8Å; Y184-F202 HydrophobicContact CD1-CB 4.31Å; Y184-F202 HydrophobicContact CD2-CB 3.9Å; Y184-F202 AromaticContact CD2-CD2 3.81Å; Y184-F202 HydrophobicContact CD2-CD2 3.81Å; Y184-F202 HydrophobicContact CD2-CG 4.18Å; Y184-F202 HydrophobicContact CE2-CB 4.36Å; Y184-F202 HydrophobicContact CE2-CD2 4.06Å; Y184-F202 HydrophobicContact CG-CB 3.89Å
185V80.4Confident75.4Confident6 Ų638.4 Ų38.44%0.03620%0.199CC..Hα-helixtrans-80.7-43.8179.5177.80000111.9R181 E182 S183 L195 Y198R181-V185 HydrophobicContact CG-CG2 4.41Å; R181-V185 WeakPolarHBondContact O-CG2 3.5Å; R181-V185 PolarHBondContact O-N 2.84Å; E182-V185 PolarHBondContact O-N 3.3Å; S183-V185 VanDerWaalsContact C-N 3.3Å; S183-V185 PolarHBondContact O-N 3.5Å; V185-L195 HydrophobicContact CG1-CD2 3.77Å; V185-L195 HydrophobicContact CG2-CD2 4.22Å; V185-Y198 HydrophobicContact CG2-CD1 4.47Å; V185-Y198 HydrophobicContact CG2-CD2 3.67Å; V185-Y198 HydrophobicContact CG2-CE2 4.32Å; V185-Y198 HydrophobicContact CG2-CG 3.76Å
186N76.2Confident75Confident35 Ų3538.8 Ų38.819%0.18720%0.201CC..Hα-helixtrans-85.9-20-172.4-62.3-38.4000113.7W97 F101 E182 C188W97-N186 HydrophobicContact CZ2-CB 4.35Å; F101-N186 HydrophobicContact CE2-CB 3.91Å; F101-N186 WeakPolarHBondContact CE2-ND2 3.44Å; F101-N186 VanDerWaalsContact CZ-ND2 3.32Å; F101-N186 WeakPolarHBondContact CZ-ND2 3.45Å; E182-N186 VanDerWaalsContact O-CB 3.23Å; E182-N186 WeakPolarHBondContact O-CB 3.41Å; E182-N186 VanDerWaalsContact O-CG 3.27Å; E182-N186 PolarHBondContact O-N 3.43Å; E182-N186 PolarHBondContact O-ND2 3.33Å; N186-C188 VanDerWaalsContact C-N 3.28Å
187L73.8Confident74.6Confident5 Ų541 Ų413%0.02621%0.213CC..THydrogen-bonded Turntrans-88.38.8176.4-61169.6000113W97 L140 W143 N144 F148 S183 S189W97-L187 HydrophobicContact CH2-CD1 3.98Å; W97-L187 HydrophobicContact CH2-CD2 3.65Å; W97-L187 HydrophobicContact CH2-CG 3.65Å; W97-L187 HydrophobicContact CZ3-CD1 4.03Å; W97-L187 HydrophobicContact CZ3-CD2 3.79Å; W97-L187 HydrophobicContact CZ3-CG 4.08Å; L140-L187 HydrophobicContact CB-CD2 4.18Å; L140-L187 HydrophobicContact CD2-CD2 3.84Å; L140-L187 WeakPolarHBondContact O-CD2 3.32Å; W143-L187 HydrophobicContact CB-CD2 4.31Å; W143-L187 HydrophobicContact CG-CD2 4.42Å; N144-L187 HydrophobicContact CB-CB 4.45Å; N144-L187 HydrophobicContact CB-CD2 4.3Å; F148-L187 HydrophobicContact CB-CD1 3.66Å; F148-L187 HydrophobicContact CD1-CD1 3.59Å; F148-L187 HydrophobicContact CD2-CD1 3.79Å; F148-L187 HydrophobicContact CE1-CD1 4.1Å; F148-L187 HydrophobicContact CE2-CD1 4.28Å; F148-L187 HydrophobicContact CG-CD1 3.4Å; F148-L187 VanDerWaalsContact CG-CD1 3.4Å; F148-L187 HydrophobicContact CZ-CD1 4.4Å; S183-L187 WeakPolarHBondContact O-CB 3.13Å; S183-L187 WeakPolarHBondContact O-CD1 3.31Å; S183-L187 WeakPolarHBondContact O-CG 3.3Å; S183-L187 PolarHBondContact O-N 3.02Å; L187-S189 PolarHBondContact O-N 2.92Å
188C66.8Low74.5Confident16 Ų1641 Ų4111%0.10821%0.213CC..  trans-76.9111.4175.2-166.80000110.7N186 N190 K194 I197N186-C188 VanDerWaalsContact C-N 3.28Å; C188-N190 VanDerWaalsContact C-N 3.3Å; C188-N190 PolarHBondContact O-N 3.23Å; C188-K194 WeakPolarHBondContact CB-O 3.43Å; C188-I197 HydrophobicContact CB-CD1 4.45Å
189S58.8Low74.3Confident52 Ų5245.4 Ų45.436%0.36423%0.228SC..  trans-83.41.7-179.3-44.80000113.9D141 L187 P191D141-S189 PolarHBondContact OD1-OG 3.37Å; L187-S189 PolarHBondContact O-N 2.92Å; S189-P191 WeakPolarHBondContact O-CD 3.46Å
190N60.9Low74.3Confident48 Ų4850 Ų5026%0.25725%0.252SS..  trans-79117-177.7-170.8-10.1000111.3C188 E192 Q196C188-N190 VanDerWaalsContact C-N 3.3Å; C188-N190 PolarHBondContact O-N 3.23Å; N190-E192 VanDerWaalsContact C-N 3.33Å; N190-E192 PolarHBondContact O-N 3.08Å; N190-E192 PolarHBondContact OD1-N 2.9Å; N190-E192 VanDerWaalsContact OD1-N 3.08Å; N190-Q196 PolarHBondContact ND2-OE1 2.98Å
191P59.2Low74.3Confident111 Ų11152.7 Ų52.772%0.72127%0.267SS*.SBendtrans-72.2-20.6-178.828.4-34.4000114.3S189S189-P191 WeakPolarHBondContact O-CD 3.46Å
192E59Low74.3Confident187 Ų18751.3 Ų51.387%0.87426%0.261SS*.SBendtrans-90-30179.7-63.8-168.8161.200112.8N190N190-E192 VanDerWaalsContact C-N 3.33Å; N190-E192 PolarHBondContact O-N 3.08Å; N190-E192 PolarHBondContact OD1-N 2.9Å; N190-E192 VanDerWaalsContact OD1-N 3.08Å
193D67Low74.5Confident43 Ų4349.6 Ų49.623%0.2325%0.254CS..  trans-145.988.3-176.4-175.8-0.9000111.5L195 Q196 R199D193-L195 PolarHBondContact O-N 3.35Å; D193-L195 PolarHBondContact OD1-N 3.49Å; D193-L195 VanDerWaalsContact OD1-N 3.11Å; D193-Q196 HydrophobicContact CB-CB 4.3Å; D193-Q196 PolarHBondContact O-N 3Å; D193-Q196 PolarHBondContact OD1-N 3.04Å; D193-R199 IonicContact OD1-CZ 3.66Å; D193-R199 IonicContact OD1-NH2 2.98Å; D193-R199 PolarHBondContact OD1-NH2 3.02Å; D193-R199 IonicContact OD2-CZ 3.41Å; D193-R199 IonicContact OD2-NH2 2.79Å; D193-R199 PolarHBondContact OD2-NH2 2.95Å
194K66.3Low74.8Confident100 Ų10055.3 Ų55.344%0.43528%0.279SS..THydrogen-bonded Turntrans-63.5-8.1-179.9-63.6-174.2179.8-175.30113.4D132 C188D132-K194 IonicContact OD1-NZ 3.84Å; C188-K194 WeakPolarHBondContact CB-O 3.43Å
195L74.1Confident75.2Confident18 Ų1856 Ų569%0.09428%0.284CS..THydrogen-bonded Turntrans-110.9-1.7-176.9-66.7172.8000114.1V185 D193 I197 Y198 R199 E250 C255V185-L195 HydrophobicContact CG1-CD2 3.77Å; V185-L195 HydrophobicContact CG2-CD2 4.22Å; D193-L195 PolarHBondContact O-N 3.35Å; D193-L195 PolarHBondContact OD1-N 3.49Å; D193-L195 VanDerWaalsContact OD1-N 3.11Å; L195-I197 PolarHBondContact O-N 2.91Å; L195-Y198 HydrophobicContact CD2-CD1 4.3Å; L195-Y198 PolarHBondContact O-N 3.41Å; L195-R199 WeakPolarHBondContact O-CG 3.31Å; L195-R199 PolarHBondContact O-N 3.34Å; L195-E250 HydrophobicContact CD2-CG 4.22Å; L195-C255 HydrophobicContact CD1-CB 3.93Å
196Q76.3Confident75.7Confident77 Ų7755.8 Ų55.836%0.3628%0.283SS..Hα-helixtrans-56.8-51.7-175-170.1178.611.800113.2N190 D193 Y198 R199 D200N190-Q196 PolarHBondContact ND2-OE1 2.98Å; D193-Q196 HydrophobicContact CB-CB 4.3Å; D193-Q196 PolarHBondContact O-N 3Å; D193-Q196 PolarHBondContact OD1-N 3.04Å; Q196-Y198 VanDerWaalsContact C-N 3.28Å; Q196-Y198 PolarHBondContact O-N 3.04Å; Q196-R199 PolarHBondContact O-N 3.36Å; Q196-R199 VanDerWaalsContact O-N 3.16Å; Q196-D200 PolarHBondContact O-N 3.13Å
197I77.6Confident76.3Confident59 Ų5955.6 Ų55.630%0.30328%0.282SS..Hα-helixtrans-65.2-34.7-177.7-62.4-178.5000111.5Y184 C188 L195 N201Y184-I197 HydrophobicContact CD1-CG2 4.14Å; C188-I197 HydrophobicContact CB-CD1 4.45Å; L195-I197 PolarHBondContact O-N 2.91Å; I197-N201 WeakPolarHBondContact O-CB 3.41Å; I197-N201 PolarHBondContact O-N 2.99Å; I197-N201 PolarHBondContact O-ND2 2.88Å
198Y83.3Confident77.1Confident0 Ų059.3 Ų59.30%030%0.302CS..Iπ-helixtrans-65.8-45174.4160.8-95.3000111.2R181 V185 L195 Q196 F202 E203 E250 S257R181-Y198 HydrophobicContact CG-CD2 4.3Å; R181-Y198 HydrophobicContact CG-CE2 3.83Å; V185-Y198 HydrophobicContact CG2-CD1 4.47Å; V185-Y198 HydrophobicContact CG2-CD2 3.67Å; V185-Y198 HydrophobicContact CG2-CE2 4.32Å; V185-Y198 HydrophobicContact CG2-CG 3.76Å; L195-Y198 HydrophobicContact CD2-CD1 4.3Å; L195-Y198 PolarHBondContact O-N 3.41Å; Q196-Y198 VanDerWaalsContact C-N 3.28Å; Q196-Y198 PolarHBondContact O-N 3.04Å; Y198-F202 HydrophobicContact CD2-CB 4.05Å; Y198-F202 HydrophobicContact CD2-CD1 4.03Å; Y198-F202 HydrophobicContact CD2-CG 4.37Å; Y198-F202 HydrophobicContact CE2-CB 4.41Å; Y198-F202 AromaticContact CE2-CD1 3.58Å; Y198-F202 HydrophobicContact CE2-CD1 3.58Å; Y198-F202 HydrophobicContact CE2-CE1 4.31Å; Y198-F202 HydrophobicContact CE2-CG 4.36Å; Y198-F202 PolarHBondContact O-N 3.35Å; Y198-E203 HydrophobicContact CE1-CB 4.18Å; Y198-E203 PolarHBondContact O-N 3.37Å; Y198-E250 HydrophobicContact CE1-CB 4.04Å; Y198-E250 HydrophobicContact CE2-CB 4.42Å; Y198-E250 PolarHBondContact OH-N 3.2Å; Y198-E250 VanDerWaalsContact OH-N 3.08Å; Y198-S257 VanDerWaalsContact CE1-OG 3.31Å; Y198-S257 WeakPolarHBondContact CE1-OG 3.3Å; Y198-S257 PolarHBondContact OH-OG 3.17Å
199R82.6Confident78.3Confident111 Ų11159.8 Ų59.842%0.41931%0.305SS..Iπ-helixtrans-64.5-48.6179-73.3-169.6-82.8165.2-11.8112.6D193 L195 Q196 N201 E203 K204D193-R199 IonicContact OD1-CZ 3.66Å; D193-R199 IonicContact OD1-NH2 2.98Å; D193-R199 PolarHBondContact OD1-NH2 3.02Å; D193-R199 IonicContact OD2-CZ 3.41Å; D193-R199 IonicContact OD2-NH2 2.79Å; D193-R199 PolarHBondContact OD2-NH2 2.95Å; L195-R199 WeakPolarHBondContact O-CG 3.31Å; L195-R199 PolarHBondContact O-N 3.34Å; Q196-R199 PolarHBondContact O-N 3.36Å; Q196-R199 VanDerWaalsContact O-N 3.16Å; R199-N201 VanDerWaalsContact C-N 3.32Å; R199-N201 PolarHBondContact O-N 3.47Å; R199-E203 WeakPolarHBondContact CG-OE2 3.17Å; R199-K204 PolarHBondContact O-N 2.89Å
200D81.6Confident79.8Confident95 Ų9557.4 Ų57.451%0.50829%0.288SS..Iπ-helixtrans-71.4-25.8-173.9-70.5-19.8000113.5Q196Q196-D200 PolarHBondContact O-N 3.13Å
201N83.9Confident81.2Confident57 Ų5757.8 Ų57.831%0.30529%0.289SS..Iπ-helixtrans-113.1-69.8-176.6-57.6-72000112.4Y184 I197 R199 A205Y184-N201 HydrophobicContact CD1-CB 4.33Å; Y184-N201 HydrophobicContact CE1-CB 3.8Å; I197-N201 WeakPolarHBondContact O-CB 3.41Å; I197-N201 PolarHBondContact O-N 2.99Å; I197-N201 PolarHBondContact O-ND2 2.88Å; R199-N201 VanDerWaalsContact C-N 3.32Å; R199-N201 PolarHBondContact O-N 3.47Å; N201-A205 WeakPolarHBondContact O-CB 3.29Å; N201-A205 PolarHBondContact O-N 2.9Å
202F86.2Confident82.7Confident0 Ų061.9 Ų61.90%029%0.29CS..Iπ-helixtrans-71.1-49.9-170.2-174.2-89.2000112.2A159 M160 V177 V180 R181 Y184 Y198 A205 Y206 L249A159-F202 HydrophobicContact CB-CE2 4.45Å; M160-F202 HydrophobicContact CE-CD2 3.93Å; M160-F202 HydrophobicContact CE-CE2 3.75Å; M160-F202 HydrophobicContact CE-CG 4.41Å; M160-F202 HydrophobicContact CE-CZ 4.09Å; V177-F202 HydrophobicContact CG1-CZ 4.05Å; V180-F202 HydrophobicContact CB-CE2 4.41Å; V180-F202 HydrophobicContact CG1-CD2 4.01Å; V180-F202 HydrophobicContact CG1-CE2 3.84Å; R181-F202 HydrophobicContact CB-CE1 4.08Å; R181-F202 HydrophobicContact CB-CZ 4.12Å; R181-F202 HydrophobicContact CG-CE1 4.3Å; Y184-F202 HydrophobicContact CD1-CB 4.31Å; Y184-F202 HydrophobicContact CD2-CB 3.9Å; Y184-F202 AromaticContact CD2-CD2 3.81Å; Y184-F202 HydrophobicContact CD2-CD2 3.81Å; Y184-F202 HydrophobicContact CD2-CG 4.18Å; Y184-F202 HydrophobicContact CE2-CB 4.36Å; Y184-F202 HydrophobicContact CE2-CD2 4.06Å; Y184-F202 HydrophobicContact CG-CB 3.89Å; Y198-F202 HydrophobicContact CD2-CB 4.05Å; Y198-F202 HydrophobicContact CD2-CD1 4.03Å; Y198-F202 HydrophobicContact CD2-CG 4.37Å; Y198-F202 HydrophobicContact CE2-CB 4.41Å; Y198-F202 AromaticContact CE2-CD1 3.58Å; Y198-F202 HydrophobicContact CE2-CD1 3.58Å; Y198-F202 HydrophobicContact CE2-CE1 4.31Å; Y198-F202 HydrophobicContact CE2-CG 4.36Å; Y198-F202 PolarHBondContact O-N 3.35Å; F202-A205 PolarHBondContact O-N 3.39Å; F202-Y206 HydrophobicContact CE1-CD2 4.35Å; F202-Y206 VanDerWaalsContact O-CB 3.27Å; F202-Y206 WeakPolarHBondContact O-CB 3.23Å; F202-Y206 PolarHBondContact O-N 2.72Å; F202-L249 HydrophobicContact CE1-CD2 4.38Å
203E87.6Confident84.3Confident20 Ų2053.8 Ų53.89%0.09325%0.252CS..Iπ-helixtrans-60.4-50.7177.3-178177.9158.400110.1Y198 R199 A205 Y206 L207 S257Y198-E203 HydrophobicContact CE1-CB 4.18Å; Y198-E203 PolarHBondContact O-N 3.37Å; R199-E203 WeakPolarHBondContact CG-OE2 3.17Å; E203-A205 PolarHBondContact O-N 3.02Å; E203-Y206 WeakPolarHBondContact O-CB 3.33Å; E203-Y206 PolarHBondContact O-N 3.29Å; E203-Y206 VanDerWaalsContact O-N 3.1Å; E203-L207 HydrophobicContact CG-CD1 4.04Å; E203-L207 HydrophobicContact CG-CG 4.3Å; E203-L207 VanDerWaalsContact O-CG 3.28Å; E203-L207 WeakPolarHBondContact O-CG 3.38Å; E203-L207 PolarHBondContact O-N 3.18Å; E203-S257 WeakPolarHBondContact OE1-CA 3.37Å; E203-S257 WeakPolarHBondContact OE2-CB 3.2Å; E203-S257 PolarHBondContact OE2-OG 2.89Å
204K88.6Confident85.4Confident120 Ų12051.8 Ų51.852%0.52224%0.241SC..Hα-helixtrans-55.3-48.8177.4-173.7175.2-179.2176.70112.8R199 Y206 L207 D208R199-K204 PolarHBondContact O-N 2.89Å; K204-Y206 VanDerWaalsContact C-N 3.29Å; K204-Y206 PolarHBondContact O-N 3.35Å; K204-L207 PolarHBondContact O-N 3.48Å; K204-D208 WeakPolarHBondContact O-CB 3.5Å; K204-D208 VanDerWaalsContact O-CG 3.23Å; K204-D208 PolarHBondContact O-N 2.84Å
205A88.8Confident86.5Confident16 Ų1654.2 Ų54.213%0.13225%0.248CC..Hα-helixtrans-66-33178.300000113Q156 M160 N201 F202 E203 S209Q156-A205 HydrophobicContact CG-CB 4.03Å; M160-A205 HydrophobicContact CE-CB 4.17Å; N201-A205 WeakPolarHBondContact O-CB 3.29Å; N201-A205 PolarHBondContact O-N 2.9Å; F202-A205 PolarHBondContact O-N 3.39Å; E203-A205 PolarHBondContact O-N 3.02Å; A205-S209 WeakPolarHBondContact O-CB 3.45Å; A205-S209 PolarHBondContact O-N 2.9Å
206Y90.2Very high87.2Confident1 Ų158.3 Ų58.30%0.00427%0.273CS..Hα-helixtrans-65.4-46.5173.3-165.2-76.7000110.8M160 V163 F202 E203 K204 T210 R244 Y248 L249 L261M160-Y206 HydrophobicContact CE-CD2 4.14Å; M160-Y206 HydrophobicContact SD-CD2 4.03Å; M160-Y206 HydrophobicContact SD-CG 4.4Å; V163-Y206 HydrophobicContact CG1-CE2 3.91Å; V163-Y206 HydrophobicContact CG2-CE2 3.9Å; F202-Y206 HydrophobicContact CE1-CD2 4.35Å; F202-Y206 VanDerWaalsContact O-CB 3.27Å; F202-Y206 WeakPolarHBondContact O-CB 3.23Å; F202-Y206 PolarHBondContact O-N 2.72Å; E203-Y206 WeakPolarHBondContact O-CB 3.33Å; E203-Y206 PolarHBondContact O-N 3.29Å; E203-Y206 VanDerWaalsContact O-N 3.1Å; K204-Y206 VanDerWaalsContact C-N 3.29Å; K204-Y206 PolarHBondContact O-N 3.35Å; Y206-T210 WeakPolarHBondContact O-CB 3.43Å; Y206-T210 PolarHBondContact O-N 3.08Å; Y206-T210 PolarHBondContact O-OG1 3.47Å; Y206-R244 WeakPolarHBondContact OH-CD 3.38Å; Y206-R244 VanDerWaalsContact OH-CG 3.31Å; Y206-R244 WeakPolarHBondContact OH-CG 3.2Å; Y206-Y248 HydrophobicContact CE2-CD2 4.41Å; Y206-L249 HydrophobicContact CD1-CD2 4.09Å; Y206-L249 HydrophobicContact CD2-CD2 4.25Å; Y206-L249 HydrophobicContact CG-CD2 3.97Å; Y206-L261 HydrophobicContact CD1-CD1 3.85Å; Y206-L261 HydrophobicContact CD1-CD2 4.19Å; Y206-L261 HydrophobicContact CE1-CD1 3.83Å; Y206-L261 HydrophobicContact CE1-CD2 3.59Å; Y206-L261 HydrophobicContact CE1-CG 4.38Å
207L90.6Very high87.8Confident32 Ų3257.8 Ų57.817%0.16827%0.271CS..Hα-helixtrans-59.5-52175.4-65.4174.4000111E203 K204 S209 T210 E211 L261 C264E203-L207 HydrophobicContact CG-CD1 4.04Å; E203-L207 HydrophobicContact CG-CG 4.3Å; E203-L207 VanDerWaalsContact O-CG 3.28Å; E203-L207 WeakPolarHBondContact O-CG 3.38Å; E203-L207 PolarHBondContact O-N 3.18Å; K204-L207 PolarHBondContact O-N 3.48Å; L207-S209 VanDerWaalsContact C-N 3.34Å; L207-S209 PolarHBondContact O-N 3.17Å; L207-T210 WeakPolarHBondContact O-CA 3.22Å; L207-T210 WeakPolarHBondContact O-CB 3.42Å; L207-T210 PolarHBondContact O-N 2.92Å; L207-E211 PolarHBondContact O-N 3.36Å; L207-L261 HydrophobicContact CD2-CB 3.76Å; L207-L261 HydrophobicContact CD2-CD1 3.69Å; L207-L261 HydrophobicContact CD2-CG 4.34Å; L207-C264 HydrophobicContact CD2-CB 3.97Å
208D90.4Very high88.4Confident82 Ų8255 Ų5544%0.43926%0.257SS..Hα-helixtrans-59.6-43.1-179.3-70.2-14.6000111.9K204 T210 R212K204-D208 WeakPolarHBondContact O-CB 3.5Å; K204-D208 VanDerWaalsContact O-CG 3.23Å; K204-D208 PolarHBondContact O-N 2.84Å; D208-T210 VanDerWaalsContact C-N 3.33Å; D208-T210 PolarHBondContact O-N 3.33Å; D208-R212 VanDerWaalsContact O-CB 3.23Å; D208-R212 WeakPolarHBondContact O-CB 3.23Å; D208-R212 PolarHBondContact O-N 3.42Å
209S90.4Very high88.7Confident27 Ų2757.2 Ų57.219%0.18927%0.271CS..Hα-helixtrans-62.6-40.6175.5177.60000111.8A205 L207 F213A205-S209 WeakPolarHBondContact O-CB 3.45Å; A205-S209 PolarHBondContact O-N 2.9Å; L207-S209 VanDerWaalsContact C-N 3.34Å; L207-S209 PolarHBondContact O-N 3.17Å; S209-F213 WeakPolarHBondContact O-CB 3.36Å; S209-F213 PolarHBondContact O-N 2.9Å; S209-F213 VanDerWaalsContact O-N 3.09Å
210T90.9Very high89Confident1 Ų154.7 Ų54.71%0.00627%0.27CS..Hα-helixtrans-68-47.9178.7-50.90000111.9R167 Y206 L207 D208 R212 F213 Y214 L261 C265R167-T210 PolarHBondContact NH1-OG1 3.22Å; R167-T210 VanDerWaalsContact NH2-CG2 3.34Å; R167-T210 PolarHBondContact NH2-OG1 3.42Å; Y206-T210 WeakPolarHBondContact O-CB 3.43Å; Y206-T210 PolarHBondContact O-N 3.08Å; Y206-T210 PolarHBondContact O-OG1 3.47Å; L207-T210 WeakPolarHBondContact O-CA 3.22Å; L207-T210 WeakPolarHBondContact O-CB 3.42Å; L207-T210 PolarHBondContact O-N 2.92Å; D208-T210 VanDerWaalsContact C-N 3.33Å; D208-T210 PolarHBondContact O-N 3.33Å; T210-R212 PolarHBondContact O-N 2.94Å; T210-F213 PolarHBondContact O-N 2.82Å; T210-Y214 HydrophobicContact CG2-CD2 3.75Å; T210-Y214 HydrophobicContact CG2-CE2 3.67Å; T210-Y214 VanDerWaalsContact O-CD2 3.3Å; T210-Y214 WeakPolarHBondContact O-CD2 3.49Å; T210-Y214 PolarHBondContact O-N 3.18Å; T210-Y214 VanDerWaalsContact O-N 3.11Å; T210-L261 HydrophobicContact CG2-CD1 3.92Å; T210-C265 VanDerWaalsContact CG2-SG 3.51Å
211E91.5Very high89.5Confident56 Ų5653.5 Ų53.526%0.26226%0.259SS..Hα-helixtrans-60.4-46.6177.7-170.2-178.6-177.700110.8L207 F213 Y214 R215 A268L207-E211 PolarHBondContact O-N 3.36Å; E211-F213 VanDerWaalsContact C-N 3.32Å; E211-F213 PolarHBondContact O-N 3.16Å; E211-Y214 PolarHBondContact O-N 3.44Å; E211-R215 HydrophobicContact CG-CG 4.25Å; E211-R215 WeakPolarHBondContact O-CB 3.22Å; E211-R215 WeakPolarHBondContact O-CG 3.12Å; E211-R215 PolarHBondContact O-N 3.18Å; E211-R215 IonicContact OE1-CZ 2.8Å; E211-R215 IonicContact OE1-NE 2.7Å; E211-R215 PolarHBondContact OE1-NE 3.49Å; E211-R215 IonicContact OE1-NH2 3.13Å; E211-R215 PolarHBondContact OE1-NH2 3.26Å; E211-A268 HydrophobicContact CG-CB 4.23Å
212R90.5Very high89.8Confident197 Ų19751.8 Ų51.874%0.74325%0.25SC*.Hα-helixtrans-62.4-39.3-179.9-172175.4-177.7176.11112.4D208 T210 T216D208-R212 VanDerWaalsContact O-CB 3.23Å; D208-R212 WeakPolarHBondContact O-CB 3.23Å; D208-R212 PolarHBondContact O-N 3.42Å; T210-R212 PolarHBondContact O-N 2.94Å; R212-T216 PolarHBondContact O-N 2.94Å; R212-T216 PolarHBondContact O-OG1 2.97Å
213F91.3Very high89.9Confident17 Ų1760 Ų608%0.07529%0.288CS..Hα-helixtrans-60.8-54.2176-178.8-100.5000111.1H164 R167 L168 S209 T210 E211 T216 Q217H164-F213 AromaticContact CE1-CD2 3.45Å; H164-F213 VanDerWaalsContact CE1-CD2 3.45Å; H164-F213 WeakPolarHBondContact CE1-CD2 3.47Å; H164-F213 AromaticContact CE1-CE2 3.77Å; H164-F213 AromaticContact ND1-CD2 3.46Å; H164-F213 WeakPolarHBondContact ND1-CD2 3.25Å; H164-F213 AromaticContact ND1-CE2 3.98Å; R167-F213 HydrophobicContact CB-CE1 3.9Å; R167-F213 HydrophobicContact CB-CE2 4.11Å; R167-F213 HydrophobicContact CB-CZ 3.65Å; R167-F213 HydrophobicContact CG-CE1 4.36Å; L168-F213 HydrophobicContact CD2-CE2 4.18Å; L168-F213 HydrophobicContact CD2-CZ 4.4Å; S209-F213 WeakPolarHBondContact O-CB 3.36Å; S209-F213 PolarHBondContact O-N 2.9Å; S209-F213 VanDerWaalsContact O-N 3.09Å; T210-F213 PolarHBondContact O-N 2.82Å; E211-F213 VanDerWaalsContact C-N 3.32Å; E211-F213 PolarHBondContact O-N 3.16Å; F213-T216 PolarHBondContact O-N 2.8Å; F213-Q217 PolarHBondContact O-N 3.11Å; F213-Q217 VanDerWaalsContact O-N 3.07Å
214Y91.2Very high90Very high1 Ų165.9 Ų65.90%0.00432%0.316CS..Hα-helixtrans-72.1-35.2-176.5-71.5-59000113.2T210 E211 T216 Q217 A218 K237 E241 L269T210-Y214 HydrophobicContact CG2-CD2 3.75Å; T210-Y214 HydrophobicContact CG2-CE2 3.67Å; T210-Y214 VanDerWaalsContact O-CD2 3.3Å; T210-Y214 WeakPolarHBondContact O-CD2 3.49Å; T210-Y214 PolarHBondContact O-N 3.18Å; T210-Y214 VanDerWaalsContact O-N 3.11Å; E211-Y214 PolarHBondContact O-N 3.44Å; Y214-T216 PolarHBondContact O-N 2.96Å; Y214-Q217 PolarHBondContact O-N 3.1Å; Y214-A218 WeakPolarHBondContact O-CB 3.32Å; Y214-A218 PolarHBondContact O-N 3.49Å; Y214-K237 HydrophobicContact CE1-CB 3.99Å; Y214-K237 HydrophobicContact CE1-CD 4.17Å; Y214-K237 HydrophobicContact CE1-CG 4.08Å; Y214-E241 HydrophobicContact CE2-CG 3.66Å; Y214-E241 VanDerWaalsContact OH-CG 3.29Å; Y214-E241 WeakPolarHBondContact OH-CG 3.46Å; Y214-E241 PolarHBondContact OH-OE1 3.29Å; Y214-L269 HydrophobicContact CD1-CD1 4.04Å; Y214-L269 HydrophobicContact CD1-CD2 3.58Å; Y214-L269 HydrophobicContact CD1-CG 4.08Å; Y214-L269 HydrophobicContact CD2-CD1 4.31Å; Y214-L269 HydrophobicContact CD2-CG 4.5Å; Y214-L269 HydrophobicContact CE1-CD1 4.2Å; Y214-L269 HydrophobicContact CE1-CD2 4.35Å; Y214-L269 HydrophobicContact CE2-CD1 4.49Å; Y214-L269 HydrophobicContact CG-CD1 4.09Å; Y214-L269 HydrophobicContact CG-CD2 3.85Å; Y214-L269 HydrophobicContact CG-CG 3.95Å
215R89.1Confident90Very high152 Ų15263.1 Ų63.157%0.57431%0.307SS*.Hα-helixtrans-59.4-29.3172.5-84.8-168.3-174.4-158.25113.1E211 P219E211-R215 HydrophobicContact CG-CG 4.25Å; E211-R215 WeakPolarHBondContact O-CB 3.22Å; E211-R215 WeakPolarHBondContact O-CG 3.12Å; E211-R215 PolarHBondContact O-N 3.18Å; E211-R215 IonicContact OE1-CZ 2.8Å; E211-R215 IonicContact OE1-NE 2.7Å; E211-R215 PolarHBondContact OE1-NE 3.49Å; E211-R215 IonicContact OE1-NH2 3.13Å; E211-R215 PolarHBondContact OE1-NH2 3.26Å; R215-P219 WeakPolarHBondContact O-CD 3.4Å; R215-P219 VanDerWaalsContact O-CG 3.28Å; R215-P219 WeakPolarHBondContact O-CG 3.36Å
216T88.8Confident90.1Very high104 Ų10464 Ų6464%0.63832%0.317SS*.Hα-helixtrans-84-43.9179.3-51.60000111.3R212 F213 Y214R212-T216 PolarHBondContact O-N 2.94Å; R212-T216 PolarHBondContact O-OG1 2.97Å; F213-T216 PolarHBondContact O-N 2.8Å; Y214-T216 PolarHBondContact O-N 2.96Å
217Q88.6Confident90.1Very high66 Ų6664.9 Ų64.931%0.30832%0.323SS..Hα-helixtrans-82.4-36.1-173.5-165176.820.700113.5F213 Y214 S220 Y221 Y233F213-Q217 PolarHBondContact O-N 3.11Å; F213-Q217 VanDerWaalsContact O-N 3.07Å; Y214-Q217 PolarHBondContact O-N 3.1Å; Q217-S220 PolarHBondContact O-N 3.31Å; Q217-Y221 PolarHBondContact O-N 3.22Å; Q217-Y233 PolarHBondContact NE2-OH 3.26Å; Q217-Y233 PolarHBondContact OE1-OH 3.13Å
218A89.9Confident89.9Confident0 Ų066 Ų660%033%0.327CS..Hα-helixtrans-62-46.6-173.600000114.3Y214 S220 Y221 L222 Y230 L269 F273Y214-A218 WeakPolarHBondContact O-CB 3.32Å; Y214-A218 PolarHBondContact O-N 3.49Å; A218-S220 VanDerWaalsContact C-N 3.33Å; A218-S220 PolarHBondContact O-N 3.04Å; A218-Y221 PolarHBondContact O-N 2.98Å; A218-L222 WeakPolarHBondContact O-CB 3.46Å; A218-L222 PolarHBondContact O-N 2.7Å; A218-Y230 HydrophobicContact CB-CE2 3.91Å; A218-Y230 WeakPolarHBondContact CB-OH 3.39Å; A218-L269 HydrophobicContact CB-CD2 3.99Å; A218-F273 HydrophobicContact CB-CE2 3.68Å; A218-F273 HydrophobicContact CB-CZ 3.99Å
219P90.1Very high89.8Confident47 Ų4765.9 Ų65.931%0.30533%0.326SS..Hα-helixtrans-61.4-40.9177.2-16.225.4000112.5R215 L222 Q223 F273R215-P219 WeakPolarHBondContact O-CD 3.4Å; R215-P219 VanDerWaalsContact O-CG 3.28Å; R215-P219 WeakPolarHBondContact O-CG 3.36Å; P219-L222 PolarHBondContact O-N 2.79Å; P219-Q223 WeakPolarHBondContact O-CG 3.42Å; P219-Q223 PolarHBondContact O-N 2.89Å; P219-F273 HydrophobicContact CB-CE1 4.45Å; P219-F273 HydrophobicContact CB-CZ 4.3Å; P219-F273 HydrophobicContact CG-CE1 4.44Å; P219-F273 HydrophobicContact CG-CZ 3.87Å
220S89.8Confident89.9Confident57 Ų5764.6 Ų64.640%0.39932%0.317SS..Hα-helixtrans-63.4-44.2179.9-174.50000111.5Q217 A218 Q223 Q224Q217-S220 PolarHBondContact O-N 3.31Å; A218-S220 VanDerWaalsContact C-N 3.33Å; A218-S220 PolarHBondContact O-N 3.04Å; S220-Q223 PolarHBondContact O-N 2.94Å; S220-Q224 WeakPolarHBondContact O-CG 3.47Å; S220-Q224 PolarHBondContact O-N 3.38Å
221Y90.3Very high89.9Confident70 Ų7064.6 Ų64.628%0.27532%0.317SS..Hα-helixtrans-66.4-41.3177.5-163.9-83.2000112.3Q217 A218 Q223 Q224 N225 Y230 Y233Q217-Y221 PolarHBondContact O-N 3.22Å; A218-Y221 PolarHBondContact O-N 2.98Å; Y221-Q223 PolarHBondContact O-N 2.97Å; Y221-Q224 PolarHBondContact O-N 3.17Å; Y221-N225 HydrophobicContact CD1-CB 4.21Å; Y221-N225 WeakPolarHBondContact CD2-ND2 3.19Å; Y221-N225 HydrophobicContact CE1-CB 3.93Å; Y221-N225 VanDerWaalsContact CE1-ND2 3.31Å; Y221-N225 WeakPolarHBondContact CE1-ND2 3.22Å; Y221-N225 WeakPolarHBondContact CE2-ND2 3.44Å; Y221-N225 WeakPolarHBondContact O-CB 3.37Å; Y221-N225 PolarHBondContact O-N 3.31Å; Y221-Y230 HydrophobicContact CD1-CD2 4.14Å; Y221-Y233 HydrophobicContact CD1-CD1 4.12Å; Y221-Y233 HydrophobicContact CD1-CD2 4.36Å; Y221-Y233 AromaticContact CD1-CG 3.9Å; Y221-Y233 HydrophobicContact CD1-CG 3.9Å; Y221-Y233 HydrophobicContact CD2-CD2 4.08Å; Y221-Y233 HydrophobicContact CD2-CE2 4.12Å; Y221-Y233 HydrophobicContact CD2-CG 4.38Å; Y221-Y233 VanDerWaalsContact CE1-CB 3.5Å; Y221-Y233 HydrophobicContact CE1-CD1 4.39Å; Y221-Y233 HydrophobicContact CE1-CD2 4.03Å; Y221-Y233 AromaticContact CE1-CG 3.72Å; Y221-Y233 HydrophobicContact CE1-CG 3.72Å; Y221-Y233 AromaticContact CE2-CD2 3.72Å; Y221-Y233 HydrophobicContact CE2-CD2 3.72Å; Y221-Y233 HydrophobicContact CE2-CE2 4.05Å; Y221-Y233 HydrophobicContact CE2-CG 4.22Å; Y221-Y233 HydrophobicContact CG-CD1 4.27Å; Y221-Y233 HydrophobicContact CG-CD2 4.38Å; Y221-Y233 HydrophobicContact CG-CE1 4.49Å; Y221-Y233 HydrophobicContact CG-CG 4.23Å; Y221-Y233 AromaticContact CZ-CD2 3.67Å; Y221-Y233 AromaticContact CZ-CG 3.88Å
222L90.6Very high89.9Confident22 Ų2267.9 Ų67.912%0.11533%0.331CS..Hα-helixtrans-61-43.8178.3-18064.8000111.7A218 P219 Q224 G226 V227 Y230 F273A218-L222 WeakPolarHBondContact O-CB 3.46Å; A218-L222 PolarHBondContact O-N 2.7Å; P219-L222 PolarHBondContact O-N 2.79Å; L222-Q224 PolarHBondContact O-N 3.4Å; L222-G226 WeakPolarHBondContact O-CA 3.41Å; L222-G226 PolarHBondContact O-N 3.26Å; L222-G226 VanDerWaalsContact O-N 3.08Å; L222-V227 HydrophobicContact CD1-CG2 4.15Å; L222-Y230 HydrophobicContact CB-CD2 3.84Å; L222-Y230 HydrophobicContact CB-CE2 4.29Å; L222-Y230 HydrophobicContact CB-CG 4.19Å; L222-Y230 HydrophobicContact CD1-CD1 4Å; L222-Y230 HydrophobicContact CD1-CD2 4.21Å; L222-Y230 HydrophobicContact CD1-CG 3.66Å; L222-Y230 HydrophobicContact CG-CG 4.48Å; L222-F273 HydrophobicContact CD2-CD1 3.41Å; L222-F273 VanDerWaalsContact CD2-CD1 3.41Å; L222-F273 HydrophobicContact CD2-CE1 3.83Å; L222-F273 HydrophobicContact CD2-CG 4.16Å
223Q89.4Confident90Very high172 Ų17259.6 Ų59.680%0.80430%0.299SS*.Hα-helixtrans-65.9-36.1179.8-74.9-178.2-0.500113.1P219 S220 Y221P219-Q223 WeakPolarHBondContact O-CG 3.42Å; P219-Q223 PolarHBondContact O-N 2.89Å; S220-Q223 PolarHBondContact O-N 2.94Å; Y221-Q223 PolarHBondContact O-N 2.97Å
224Q90Very high90Very high144 Ų14458.8 Ų58.867%0.67330%0.296SS*.Hα-helixtrans-81.6-38.5-176.7-68.6176.19.200113.1S220 Y221 L222S220-Q224 WeakPolarHBondContact O-CG 3.47Å; S220-Q224 PolarHBondContact O-N 3.38Å; Y221-Q224 PolarHBondContact O-N 3.17Å; L222-Q224 PolarHBondContact O-N 3.4Å
225N87.9Confident90Very high62 Ų6259.7 Ų59.733%0.33230%0.301SS..Hα-helixtrans-112.4-7.8-165.5-60.1-30.3000113.9Y221 N229Y221-N225 HydrophobicContact CD1-CB 4.21Å; Y221-N225 WeakPolarHBondContact CD2-ND2 3.19Å; Y221-N225 HydrophobicContact CE1-CB 3.93Å; Y221-N225 VanDerWaalsContact CE1-ND2 3.31Å; Y221-N225 WeakPolarHBondContact CE1-ND2 3.22Å; Y221-N225 WeakPolarHBondContact CE2-ND2 3.44Å; Y221-N225 WeakPolarHBondContact O-CB 3.37Å; Y221-N225 PolarHBondContact O-N 3.31Å; N225-N229 HydrophobicContact CB-CB 3.97Å; N225-N229 PolarHBondContact O-ND2 3.27Å
226G90.3Very high90.1Very high33 Ų3354.4 Ų54.434%0.3429%0.29SS..Hα-helixtrans76.6170.7-178.500000114.3L222 Q228 Y230L222-G226 WeakPolarHBondContact O-CA 3.41Å; L222-G226 PolarHBondContact O-N 3.26Å; L222-G226 VanDerWaalsContact O-N 3.08Å; G226-Q228 PolarHBondContact O-N 3.35Å; G226-Y230 WeakPolarHBondContact O-CB 3.39Å; G226-Y230 PolarHBondContact O-N 2.96Å
227V89.8Confident90.3Very high21 Ų2150.9 Ų50.913%0.12727%0.266CS..Hα-helixtrans-61.4-41.2-171.5-177.40000112.8L222 Y230 M231 T276 I277 E280L222-V227 HydrophobicContact CD1-CG2 4.15Å; V227-Y230 WeakPolarHBondContact O-CB 3.48Å; V227-Y230 PolarHBondContact O-N 3.02Å; V227-M231 WeakPolarHBondContact O-CG 3.4Å; V227-M231 PolarHBondContact O-N 3.44Å; V227-T276 HydrophobicContact CG2-CG2 3.89Å; V227-I277 HydrophobicContact CG1-CB 4.39Å; V227-I277 HydrophobicContact CG1-CG1 4.12Å; V227-E280 HydrophobicContact CB-CG 4.02Å; V227-E280 HydrophobicContact CG1-CG 4Å; V227-E280 HydrophobicContact CG2-CG 4.11Å
228Q86.6Confident90.4Very high54 Ų5447.9 Ų47.925%0.25225%0.252SS..Hα-helixtrans-67.3-43.4-173.9-53.7-168.1300112.7G226 Y230 M231 K232 M284 K292G226-Q228 PolarHBondContact O-N 3.35Å; Q228-Y230 VanDerWaalsContact C-N 3.33Å; Q228-M231 PolarHBondContact O-N 2.56Å; Q228-K232 PolarHBondContact O-N 2.86Å; Q228-M284 HydrophobicContact CG-CE 3.71Å; Q228-K292 VanDerWaalsContact OE1-CE 3.31Å
229N89.4Confident90.5Very high80 Ų8054.7 Ų54.743%0.42828%0.277SS..Hα-helixtrans-72-33.8175.6-67.6-39.5000110.9N225 M231 K232 Y233N225-N229 HydrophobicContact CB-CB 3.97Å; N225-N229 PolarHBondContact O-ND2 3.27Å; N229-M231 VanDerWaalsContact C-N 3.34Å; N229-M231 PolarHBondContact O-N 3.47Å; N229-K232 PolarHBondContact O-N 2.59Å; N229-Y233 WeakPolarHBondContact O-CB 3.34Å; N229-Y233 PolarHBondContact O-N 3.31Å
230Y92.3Very high90.5Very high0 Ų056.2 Ų56.20%028%0.281CS..Hα-helixtrans-60-40.7173-179-97.6000112.5A218 Y221 L222 G226 V227 Q228 K232 Y233 A234 L269 F273 I277A218-Y230 HydrophobicContact CB-CE2 3.91Å; A218-Y230 WeakPolarHBondContact CB-OH 3.39Å; Y221-Y230 HydrophobicContact CD1-CD2 4.14Å; L222-Y230 HydrophobicContact CB-CD2 3.84Å; L222-Y230 HydrophobicContact CB-CE2 4.29Å; L222-Y230 HydrophobicContact CB-CG 4.19Å; L222-Y230 HydrophobicContact CD1-CD1 4Å; L222-Y230 HydrophobicContact CD1-CD2 4.21Å; L222-Y230 HydrophobicContact CD1-CG 3.66Å; L222-Y230 HydrophobicContact CG-CG 4.48Å; G226-Y230 WeakPolarHBondContact O-CB 3.39Å; G226-Y230 PolarHBondContact O-N 2.96Å; V227-Y230 WeakPolarHBondContact O-CB 3.48Å; V227-Y230 PolarHBondContact O-N 3.02Å; Q228-Y230 VanDerWaalsContact C-N 3.33Å; Y230-K232 PolarHBondContact O-N 3.08Å; Y230-Y233 HydrophobicContact CD2-CD1 4.43Å; Y230-Y233 HydrophobicContact CE2-CD1 4.39Å; Y230-Y233 CarbonylContact O-C 3.58Å; Y230-Y233 WeakPolarHBondContact O-CB 3.3Å; Y230-Y233 PolarHBondContact O-N 3.46Å; Y230-A234 HydrophobicContact CE1-CB 4.39Å; Y230-A234 WeakPolarHBondContact O-CB 3.37Å; Y230-A234 PolarHBondContact O-N 3.36Å; Y230-L269 WeakPolarHBondContact CE1-O 3.34Å; Y230-L269 PolarHBondContact OH-O 3.3Å; Y230-F273 HydrophobicContact CE1-CB 4.27Å; Y230-F273 HydrophobicContact CE1-CD2 4.16Å; Y230-F273 HydrophobicContact CE1-CG 4.33Å; Y230-F273 AromaticContact CZ-CD2 3.84Å; Y230-F273 WeakPolarHBondContact OH-CD2 3.49Å; Y230-F273 WeakPolarHBondContact OH-CE2 3.48Å; Y230-I277 HydrophobicContact CD1-CD1 4.47Å; Y230-I277 HydrophobicContact CE1-CD1 4.33Å
231M90.5Very high90.6Very high1 Ų153.5 Ų53.51%0.00526%0.262CS..Hα-helixtrans-60.6-43.4175.2-70.8-170.4-67.900112.2V227 Q228 N229 Y233 A234 D235 I277 M284 L295 M296 L299V227-M231 WeakPolarHBondContact O-CG 3.4Å; V227-M231 PolarHBondContact O-N 3.44Å; Q228-M231 PolarHBondContact O-N 2.56Å; N229-M231 VanDerWaalsContact C-N 3.34Å; N229-M231 PolarHBondContact O-N 3.47Å; M231-Y233 VanDerWaalsContact C-N 3.31Å; M231-Y233 PolarHBondContact O-N 3.44Å; M231-A234 PolarHBondContact O-N 3.36Å; M231-D235 PolarHBondContact O-N 3.47Å; M231-I277 HydrophobicContact CG-CG2 4.14Å; M231-I277 HydrophobicContact SD-CG2 3.69Å; M231-M284 HydrophobicContact CE-CE 3.49Å; M231-M284 VanDerWaalsContact CE-CE 3.49Å; M231-M284 HydrophobicContact CE-SD 4.16Å; M231-L295 HydrophobicContact CB-CD2 3.75Å; M231-L295 HydrophobicContact CB-CG 4.16Å; M231-M296 HydrophobicContact SD-CB 3.72Å; M231-M296 HydrophobicContact SD-CG 3.94Å; M231-M296 HydrophobicContact SD-SD 4.48Å; M231-L299 HydrophobicContact CB-CD1 3.73Å; M231-L299 HydrophobicContact CG-CD1 3.94Å
232K91.9Very high90.6Very high126 Ų12654.3 Ų54.355%0.54827%0.268SS..Hα-helixtrans-63.4-41.2176.5-69.3-178.5178-177.70111.2Q228 N229 Y230 A236 L295Q228-K232 PolarHBondContact O-N 2.86Å; N229-K232 PolarHBondContact O-N 2.59Å; Y230-K232 PolarHBondContact O-N 3.08Å; K232-A236 WeakPolarHBondContact O-CB 3.34Å; K232-A236 PolarHBondContact O-N 3.07Å; K232-L295 HydrophobicContact CB-CD2 4.3Å; K232-L295 HydrophobicContact CG-CD2 3.51Å
233Y91.4Very high90.6Very high22 Ų2260.7 Ų60.79%0.08630%0.295CS..Hα-helixtrans-61.8-47.4175.2176.4-96.8000111.7Q217 Y221 N229 Y230 M231 A236 K237Q217-Y233 PolarHBondContact NE2-OH 3.26Å; Q217-Y233 PolarHBondContact OE1-OH 3.13Å; Y221-Y233 HydrophobicContact CD1-CD1 4.12Å; Y221-Y233 HydrophobicContact CD1-CD2 4.36Å; Y221-Y233 AromaticContact CD1-CG 3.9Å; Y221-Y233 HydrophobicContact CD1-CG 3.9Å; Y221-Y233 HydrophobicContact CD2-CD2 4.08Å; Y221-Y233 HydrophobicContact CD2-CE2 4.12Å; Y221-Y233 HydrophobicContact CD2-CG 4.38Å; Y221-Y233 VanDerWaalsContact CE1-CB 3.5Å; Y221-Y233 HydrophobicContact CE1-CD1 4.39Å; Y221-Y233 HydrophobicContact CE1-CD2 4.03Å; Y221-Y233 AromaticContact CE1-CG 3.72Å; Y221-Y233 HydrophobicContact CE1-CG 3.72Å; Y221-Y233 AromaticContact CE2-CD2 3.72Å; Y221-Y233 HydrophobicContact CE2-CD2 3.72Å; Y221-Y233 HydrophobicContact CE2-CE2 4.05Å; Y221-Y233 HydrophobicContact CE2-CG 4.22Å; Y221-Y233 HydrophobicContact CG-CD1 4.27Å; Y221-Y233 HydrophobicContact CG-CD2 4.38Å; Y221-Y233 HydrophobicContact CG-CE1 4.49Å; Y221-Y233 HydrophobicContact CG-CG 4.23Å; Y221-Y233 AromaticContact CZ-CD2 3.67Å; Y221-Y233 AromaticContact CZ-CG 3.88Å; N229-Y233 WeakPolarHBondContact O-CB 3.34Å; N229-Y233 PolarHBondContact O-N 3.31Å; Y230-Y233 HydrophobicContact CD2-CD1 4.43Å; Y230-Y233 HydrophobicContact CE2-CD1 4.39Å; Y230-Y233 CarbonylContact O-C 3.58Å; Y230-Y233 WeakPolarHBondContact O-CB 3.3Å; Y230-Y233 PolarHBondContact O-N 3.46Å; M231-Y233 VanDerWaalsContact C-N 3.31Å; M231-Y233 PolarHBondContact O-N 3.44Å; Y233-A236 PolarHBondContact O-N 2.9Å; Y233-K237 HydrophobicContact CD1-CG 4.27Å; Y233-K237 HydrophobicContact CD2-CG 4.22Å; Y233-K237 HydrophobicContact CE1-CG 3.85Å; Y233-K237 HydrophobicContact CE2-CD 4.21Å; Y233-K237 VanDerWaalsContact CE2-CE 3.46Å; Y233-K237 HydrophobicContact CE2-CG 3.82Å; Y233-K237 HydrophobicContact CG-CG 4.42Å; Y233-K237 WeakPolarHBondContact O-CB 3.34Å; Y233-K237 VanDerWaalsContact O-CG 3.29Å; Y233-K237 WeakPolarHBondContact O-CG 3.41Å; Y233-K237 PolarHBondContact O-N 3.23Å
234A91.6Very high90.6Very high1 Ų153.6 Ų53.61%0.00826%0.26CS..Hα-helixtrans-61.7-46.4179.200000111.7Y230 M231 K237 L238 L299Y230-A234 HydrophobicContact CE1-CB 4.39Å; Y230-A234 WeakPolarHBondContact O-CB 3.37Å; Y230-A234 PolarHBondContact O-N 3.36Å; M231-A234 PolarHBondContact O-N 3.36Å; A234-K237 PolarHBondContact O-N 3.4Å; A234-L238 WeakPolarHBondContact O-CB 3.41Å; A234-L238 VanDerWaalsContact O-CG 3.22Å; A234-L238 WeakPolarHBondContact O-CG 3.41Å; A234-L238 PolarHBondContact O-N 2.99Å; A234-L299 HydrophobicContact CB-CD2 4.4Å
235D91.4Very high90.6Very high19 Ų1946.8 Ų46.810%0.10223%0.228CC..Hα-helixtrans-62.4-45.1176.6-177.663.2000112M231 K237 L238 R239 L295 L299M231-D235 PolarHBondContact O-N 3.47Å; D235-K237 PolarHBondContact O-N 3.09Å; D235-L238 PolarHBondContact O-N 3.41Å; D235-R239 WeakPolarHBondContact O-CG 3.44Å; D235-R239 PolarHBondContact O-N 2.92Å; D235-R239 IonicContact OD1-NE 3.45Å; D235-R239 IonicContact OD1-NH2 3.33Å; D235-R239 IonicContact OD2-CZ 3.55Å; D235-R239 IonicContact OD2-NE 3.59Å; D235-R239 PolarHBondContact OD2-NE 3.44Å; D235-R239 IonicContact OD2-NH2 3.57Å; D235-R239 PolarHBondContact OD2-NH2 3.23Å; D235-L295 HydrophobicContact CB-CD1 3.63Å; D235-L299 HydrophobicContact CB-CD2 4.09Å
236A92.1Very high90.6Very high41 Ų4148.6 Ų48.634%0.33924%0.238SC..Hα-helixtrans-60-45.4176.500000111.7K232 Y233 R239 E240K232-A236 WeakPolarHBondContact O-CB 3.34Å; K232-A236 PolarHBondContact O-N 3.07Å; Y233-A236 PolarHBondContact O-N 2.9Å; A236-R239 PolarHBondContact O-N 3.03Å; A236-E240 WeakPolarHBondContact O-CG 3.45Å; A236-E240 PolarHBondContact O-N 2.88Å
237K91.4Very high90.4Very high31 Ų3152.9 Ų52.914%0.13524%0.244CC..Hα-helixtrans-68-36.1179-68.8-62.8168-163.20113.1Y214 Y233 A234 D235 E240 E241 L269Y214-K237 HydrophobicContact CE1-CB 3.99Å; Y214-K237 HydrophobicContact CE1-CD 4.17Å; Y214-K237 HydrophobicContact CE1-CG 4.08Å; Y233-K237 HydrophobicContact CD1-CG 4.27Å; Y233-K237 HydrophobicContact CD2-CG 4.22Å; Y233-K237 HydrophobicContact CE1-CG 3.85Å; Y233-K237 HydrophobicContact CE2-CD 4.21Å; Y233-K237 VanDerWaalsContact CE2-CE 3.46Å; Y233-K237 HydrophobicContact CE2-CG 3.82Å; Y233-K237 HydrophobicContact CG-CG 4.42Å; Y233-K237 WeakPolarHBondContact O-CB 3.34Å; Y233-K237 VanDerWaalsContact O-CG 3.29Å; Y233-K237 WeakPolarHBondContact O-CG 3.41Å; Y233-K237 PolarHBondContact O-N 3.23Å; A234-K237 PolarHBondContact O-N 3.4Å; D235-K237 PolarHBondContact O-N 3.09Å; K237-E240 WeakPolarHBondContact CD-OE2 3.48Å; K237-E240 IonicContact NZ-OE1 2.74Å; K237-E240 IonicContact NZ-OE2 3.72Å; K237-E240 PolarHBondContact NZ-OE2 3.12Å; K237-E240 PolarHBondContact O-N 3.38Å; K237-E241 WeakPolarHBondContact O-CG 3.4Å; K237-E241 PolarHBondContact O-N 2.86Å; K237-L269 HydrophobicContact CB-CD1 4.13Å
238L91.6Very high90.2Very high2 Ų251.9 Ų51.91%0.0124%0.237CC..Hα-helixtrans-62.1-44.6172.2-73170.6000111.4A234 D235 E241 E242 M262 C265 V266 L269 V270 L299 K302A234-L238 WeakPolarHBondContact O-CB 3.41Å; A234-L238 VanDerWaalsContact O-CG 3.22Å; A234-L238 WeakPolarHBondContact O-CG 3.41Å; A234-L238 PolarHBondContact O-N 2.99Å; D235-L238 PolarHBondContact O-N 3.41Å; L238-E241 PolarHBondContact O-N 2.87Å; L238-E242 WeakPolarHBondContact O-CB 3.19Å; L238-E242 PolarHBondContact O-N 3.4Å; L238-M262 HydrophobicContact CB-CE 4.15Å; L238-M262 HydrophobicContact CD2-CE 4.08Å; L238-M262 WeakPolarHBondContact O-CE 3.46Å; L238-C265 HydrophobicContact CD2-CB 3.61Å; L238-V266 HydrophobicContact CD1-CG2 4.29Å; L238-V266 HydrophobicContact CD2-CG2 3.9Å; L238-L269 HydrophobicContact CD2-CD1 4.23Å; L238-L269 HydrophobicContact CG-CD1 4.3Å; L238-V270 HydrophobicContact CD1-CG2 4.04Å; L238-L299 HydrophobicContact CD1-CD2 3.83Å; L238-K302 HydrophobicContact CD1-CD 4.39Å
239R91.2Very high90.2Very high143 Ų14349.3 Ų49.354%0.5423%0.226SC..Hα-helixtrans-66-37176.5-66.6179.5-160.3-142.26.6112.8D235 A236 K243D235-R239 WeakPolarHBondContact O-CG 3.44Å; D235-R239 PolarHBondContact O-N 2.92Å; D235-R239 IonicContact OD1-NE 3.45Å; D235-R239 IonicContact OD1-NH2 3.33Å; D235-R239 IonicContact OD2-CZ 3.55Å; D235-R239 IonicContact OD2-NE 3.59Å; D235-R239 PolarHBondContact OD2-NE 3.44Å; D235-R239 IonicContact OD2-NH2 3.57Å; D235-R239 PolarHBondContact OD2-NH2 3.23Å; A236-R239 PolarHBondContact O-N 3.03Å; R239-K243 WeakPolarHBondContact O-CG 3.36Å; R239-K243 PolarHBondContact O-N 3.22Å
240E91Very high89.8Confident80 Ų8046.1 Ų46.137%0.37421%0.208SC..Hα-helixtrans-64.8-46.5174.4-76.4175.5-162.500111.4A236 K237 K243 R244A236-E240 WeakPolarHBondContact O-CG 3.45Å; A236-E240 PolarHBondContact O-N 2.88Å; K237-E240 WeakPolarHBondContact CD-OE2 3.48Å; K237-E240 IonicContact NZ-OE1 2.74Å; K237-E240 IonicContact NZ-OE2 3.72Å; K237-E240 PolarHBondContact NZ-OE2 3.12Å; K237-E240 PolarHBondContact O-N 3.38Å; E240-K243 PolarHBondContact O-N 3.01Å; E240-R244 WeakPolarHBondContact O-CB 3.27Å; E240-R244 PolarHBondContact O-N 2.87Å
241E91.8Very high89.2Confident0 Ų050 Ų500%023%0.232CC..Hα-helixtrans-65.2-37.3176.4-72.8-58.5149.200112.2R167 Y214 K237 L238 K243 R244 A245R167-E241 IonicContact CZ-OE1 2.62Å; R167-E241 IonicContact CZ-OE2 3.78Å; R167-E241 IonicContact NE-OE1 2.8Å; R167-E241 PolarHBondContact NE-OE1 3.33Å; R167-E241 IonicContact NE-OE2 3.73Å; R167-E241 IonicContact NH2-OE1 3.12Å; R167-E241 PolarHBondContact NH2-OE1 2.95Å; R167-E241 IonicContact NH2-OE2 3.55Å; R167-E241 PolarHBondContact NH2-OE2 3.04Å; Y214-E241 HydrophobicContact CE2-CG 3.66Å; Y214-E241 VanDerWaalsContact OH-CG 3.29Å; Y214-E241 WeakPolarHBondContact OH-CG 3.46Å; Y214-E241 PolarHBondContact OH-OE1 3.29Å; K237-E241 WeakPolarHBondContact O-CG 3.4Å; K237-E241 PolarHBondContact O-N 2.86Å; L238-E241 PolarHBondContact O-N 2.87Å; E241-K243 PolarHBondContact O-N 3.42Å; E241-R244 VanDerWaalsContact CD-NH1 3.25Å; E241-R244 CarbonylContact O-C 3.48Å; E241-R244 PolarHBondContact O-N 3.49Å; E241-R244 IonicContact OE1-CZ 3.66Å; E241-R244 IonicContact OE1-NH1 3.45Å; E241-R244 PolarHBondContact OE1-NH1 3.42Å; E241-R244 IonicContact OE2-NH1 2.91Å; E241-A245 VanDerWaalsContact O-CB 3.23Å; E241-A245 WeakPolarHBondContact O-CB 3.3Å; E241-A245 PolarHBondContact O-N 3.1Å
242E90.8Very high88.6Confident87 Ų8755.1 Ų55.141%0.40725%0.251SS..Hα-helixtrans-60.3-46.7175.4-174175.7-158.200111.4L238 R244 A245 L246 M262L238-E242 WeakPolarHBondContact O-CB 3.19Å; L238-E242 PolarHBondContact O-N 3.4Å; E242-R244 VanDerWaalsContact C-N 3.29Å; E242-R244 PolarHBondContact O-N 3.22Å; E242-A245 WeakPolarHBondContact O-CB 3.46Å; E242-A245 PolarHBondContact O-N 3.12Å; E242-L246 WeakPolarHBondContact O-CG 3.48Å; E242-L246 PolarHBondContact O-N 3.14Å; E242-M262 HydrophobicContact CB-CE 4.05Å; E242-M262 HydrophobicContact CB-SD 3.73Å; E242-M262 HydrophobicContact CG-SD 4.32Å
243K90.6Very high87.2Confident156 Ų15661.3 Ų61.368%0.67827%0.271SS*.Hα-helixtrans-61.6-39.2174.9-72.3175.4-178.2178.10111.9R239 E240 E241 R247R239-K243 WeakPolarHBondContact O-CG 3.36Å; R239-K243 PolarHBondContact O-N 3.22Å; E240-K243 PolarHBondContact O-N 3.01Å; E241-K243 PolarHBondContact O-N 3.42Å; K243-R247 PolarHBondContact O-N 3.31Å
244R89.9Confident85.8Confident23 Ų2368.8 Ų68.89%0.08731%0.307CS..Hα-helixtrans-68.9-40178-169-177.6-76.8104.44.6111.6E166 Y206 E240 E241 E242 R247 Y248E166-R244 IonicContact OE2-CZ 3.21Å; E166-R244 IonicContact OE2-NE 3.51Å; E166-R244 PolarHBondContact OE2-NE 3.44Å; E166-R244 IonicContact OE2-NH2 3.55Å; Y206-R244 WeakPolarHBondContact OH-CD 3.38Å; Y206-R244 VanDerWaalsContact OH-CG 3.31Å; Y206-R244 WeakPolarHBondContact OH-CG 3.2Å; E240-R244 WeakPolarHBondContact O-CB 3.27Å; E240-R244 PolarHBondContact O-N 2.87Å; E241-R244 VanDerWaalsContact CD-NH1 3.25Å; E241-R244 CarbonylContact O-C 3.48Å; E241-R244 PolarHBondContact O-N 3.49Å; E241-R244 IonicContact OE1-CZ 3.66Å; E241-R244 IonicContact OE1-NH1 3.45Å; E241-R244 PolarHBondContact OE1-NH1 3.42Å; E241-R244 IonicContact OE2-NH1 2.91Å; E242-R244 VanDerWaalsContact C-N 3.29Å; E242-R244 PolarHBondContact O-N 3.22Å; R244-R247 WeakPolarHBondContact O-CB 3.37Å; R244-R247 PolarHBondContact O-N 2.85Å; R244-R247 VanDerWaalsContact O-N 3.08Å; R244-Y248 HydrophobicContact CG-CD2 3.4Å; R244-Y248 HydrophobicContact CG-CE2 3.5Å; R244-Y248 PolarHBondContact O-N 3.23Å
245A88.4Confident84.8Confident0 Ų069.5 Ų69.50%031%0.311CS..Hα-helixtrans-58.9-49.1175.600000111E241 E242 R247 Y248 L249 V258 L261E241-A245 VanDerWaalsContact O-CB 3.23Å; E241-A245 WeakPolarHBondContact O-CB 3.3Å; E241-A245 PolarHBondContact O-N 3.1Å; E242-A245 WeakPolarHBondContact O-CB 3.46Å; E242-A245 PolarHBondContact O-N 3.12Å; A245-R247 PolarHBondContact O-N 3.25Å; A245-R247 VanDerWaalsContact O-N 3.17Å; A245-Y248 PolarHBondContact O-N 2.97Å; A245-L249 HydrophobicContact CB-CD1 4.13Å; A245-L249 WeakPolarHBondContact O-CA 3.28Å; A245-L249 VanDerWaalsContact O-CB 3.3Å; A245-L249 WeakPolarHBondContact O-CB 3.47Å; A245-L249 PolarHBondContact O-N 2.82Å; A245-V258 HydrophobicContact CB-CB 4.41Å; A245-V258 HydrophobicContact CB-CG1 3.87Å; A245-V258 HydrophobicContact CB-CG2 4.18Å; A245-L261 HydrophobicContact CB-CD2 3.54Å
246L87.7Confident84.4Confident101 Ų10174 Ų7453%0.52934%0.335SS..Hα-helixtrans-61.3-24.4176.9-69.6170.4000112.7E242 T251 V258E242-L246 WeakPolarHBondContact O-CG 3.48Å; E242-L246 PolarHBondContact O-N 3.14Å; L246-T251 HydrophobicContact CD2-CG2 4.31Å; L246-V258 HydrophobicContact CD2-CG1 4.48Å
247R86.8Confident83.9Confident122 Ų12272 Ų7246%0.4632%0.32SS..Hα-helixtrans-86-41.7178.3-166.9-179.5-167.5179.56.6113.1E166 S174 K243 R244 A245E166-R247 IonicContact OE1-NH1 3.96Å; S174-R247 VanDerWaalsContact CB-NH2 3.29Å; S174-R247 PolarHBondContact OG-NE 3.49Å; S174-R247 PolarHBondContact OG-NH1 2.87Å; S174-R247 PolarHBondContact OG-NH2 2.94Å; K243-R247 PolarHBondContact O-N 3.31Å; R244-R247 WeakPolarHBondContact O-CB 3.37Å; R244-R247 PolarHBondContact O-N 2.85Å; R244-R247 VanDerWaalsContact O-N 3.08Å; A245-R247 PolarHBondContact O-N 3.25Å; A245-R247 VanDerWaalsContact O-N 3.17Å
248Y86.3Confident83.6Confident0 Ų071.9 Ų71.90%032%0.321CS..Hα-helixtrans-112-18.7-167.9-62.1-37000115.9V163 E166 F172 S174 V177 I178 R181 Y206 R244 A245V163-Y248 HydrophobicContact CG2-CD2 4.26Å; V163-Y248 HydrophobicContact CG2-CE2 4.41Å; E166-Y248 PolarHBondContact OE1-OH 2.91Å; E166-Y248 VanDerWaalsContact OE1-OH 3.14Å; E166-Y248 WeakPolarHBondContact OE2-CE2 3.3Å; E166-Y248 PolarHBondContact OE2-OH 2.94Å; F172-Y248 HydrophobicContact CZ-CE2 4.24Å; F172-Y248 AromaticContact CZ-CZ 3.81Å; F172-Y248 VanDerWaalsContact CZ-OH 3.31Å; F172-Y248 WeakPolarHBondContact CZ-OH 3.45Å; S174-Y248 PolarHBondContact OG-OH 3.2Å; V177-Y248 HydrophobicContact CB-CD1 3.99Å; V177-Y248 HydrophobicContact CB-CE1 4.14Å; V177-Y248 HydrophobicContact CB-CG 4.44Å; V177-Y248 HydrophobicContact CG1-CD1 3.8Å; V177-Y248 HydrophobicContact CG1-CD2 4.34Å; V177-Y248 HydrophobicContact CG1-CE1 4.39Å; V177-Y248 HydrophobicContact CG1-CG 3.81Å; I178-Y248 HydrophobicContact CG1-CD1 4.08Å; I178-Y248 HydrophobicContact CG1-CE1 4.47Å; R181-Y248 VanDerWaalsContact CD-O 3.22Å; R181-Y248 WeakPolarHBondContact CD-O 3.38Å; Y206-Y248 HydrophobicContact CE2-CD2 4.41Å; R244-Y248 HydrophobicContact CG-CD2 3.4Å; R244-Y248 HydrophobicContact CG-CE2 3.5Å; R244-Y248 PolarHBondContact O-N 3.23Å; A245-Y248 PolarHBondContact O-N 2.97Å
249L85.2Confident83.4Confident1 Ų177.1 Ų77.11%0.00535%0.345CS..SBendtrans-91.7167.7173.8-61-178.2000110.4R181 F202 Y206 A245 V258 L261R181-L249 PolarHBondContact NH1-O 3.34Å; F202-L249 HydrophobicContact CE1-CD2 4.38Å; Y206-L249 HydrophobicContact CD1-CD2 4.09Å; Y206-L249 HydrophobicContact CD2-CD2 4.25Å; Y206-L249 HydrophobicContact CG-CD2 3.97Å; A245-L249 HydrophobicContact CB-CD1 4.13Å; A245-L249 WeakPolarHBondContact O-CA 3.28Å; A245-L249 VanDerWaalsContact O-CB 3.3Å; A245-L249 WeakPolarHBondContact O-CB 3.47Å; A245-L249 PolarHBondContact O-N 2.82Å; L249-V258 HydrophobicContact CB-CG2 4.24Å; L249-L261 HydrophobicContact CD1-CB 3.87Å; L249-L261 HydrophobicContact CD1-CD2 3.68Å; L249-L261 HydrophobicContact CD1-CG 4.37Å
250E81.2Confident83.2Confident12 Ų1271.8 Ų71.86%0.05633%0.332CS..  trans-75.6129.5174.5-17755-92.200110.1L195 Y198 R252 C255L195-E250 HydrophobicContact CD2-CG 4.22Å; Y198-E250 HydrophobicContact CE1-CB 4.04Å; Y198-E250 HydrophobicContact CE2-CB 4.42Å; Y198-E250 PolarHBondContact OH-N 3.2Å; Y198-E250 VanDerWaalsContact OH-N 3.08Å; E250-R252 HydrophobicContact CG-CB 4.2Å; E250-R252 HydrophobicContact CG-CG 4.41Å; E250-R252 WeakPolarHBondContact OE1-CG 3.45Å; E250-R252 PolarHBondContact OE1-N 3.48Å; E250-R252 VanDerWaalsContact OE1-N 3.15Å; E250-R252 IonicContact OE1-NE 3.66Å; E250-R252 PolarHBondContact OE1-NE 2.93Å; E250-R252 IonicContact OE2-CZ 2.76Å; E250-R252 VanDerWaalsContact OE2-CZ 3.28Å; E250-R252 IonicContact OE2-NE 2.7Å; E250-R252 PolarHBondContact OE2-NE 3.33Å; E250-R252 IonicContact OE2-NH2 3.92Å; E250-R252 PolarHBondContact OE2-NH2 3.33Å; E250-C255 HydrophobicContact CB-CB 4.49Å; E250-C255 HydrophobicContact CG-CB 4.17Å
251T80.7Confident83.2Confident82 Ų8268 Ų6850%0.50331%0.314SS..  trans-112.68.4-174.960.80000112.7L246 V258L246-T251 HydrophobicContact CD2-CG2 4.31Å; T251-V258 HydrophobicContact CG2-CG2 4.45Å
252R77.1Confident83.2Confident109 Ų10969.1 Ų69.141%0.41132%0.32SS..SBendtrans-55.6144.9171-79.3178.6-120.1-160.8-1.6110.6E250 E254 C255E250-R252 HydrophobicContact CG-CB 4.2Å; E250-R252 HydrophobicContact CG-CG 4.41Å; E250-R252 WeakPolarHBondContact OE1-CG 3.45Å; E250-R252 PolarHBondContact OE1-N 3.48Å; E250-R252 VanDerWaalsContact OE1-N 3.15Å; E250-R252 IonicContact OE1-NE 3.66Å; E250-R252 PolarHBondContact OE1-NE 2.93Å; E250-R252 IonicContact OE2-CZ 2.76Å; E250-R252 VanDerWaalsContact OE2-CZ 3.28Å; E250-R252 IonicContact OE2-NE 2.7Å; E250-R252 PolarHBondContact OE2-NE 3.33Å; E250-R252 IonicContact OE2-NH2 3.92Å; E250-R252 PolarHBondContact OE2-NH2 3.33Å; R252-E254 PolarHBondContact O-N 3.31Å; R252-C255 WeakPolarHBondContact O-CB 3.48Å; R252-C255 PolarHBondContact O-N 3.09Å
253R62.3Low83.1Confident256 Ų25669.9 Ų69.997%0.96632%0.324SS*.THydrogen-bonded Turntrans-56.2-19.7-174.3-75.9-175.4177.5-172.4-1115.3
254E63.7Low83.1Confident179 Ų17963.5 Ų63.584%0.83630%0.298SS*.THydrogen-bonded Turntrans-93.5-2.3-178.8-64.7169.4-171.700112.7R252R252-E254 PolarHBondContact O-N 3.31Å
255C70.8Confident83.1Confident15 Ų1562.4 Ų62.410%0.10129%0.294CS..  trans-113.2117.5-172.7-157.10000111.7L195 E250 R252 S257L195-C255 HydrophobicContact CD1-CB 3.93Å; E250-C255 HydrophobicContact CB-CB 4.49Å; E250-C255 HydrophobicContact CG-CB 4.17Å; R252-C255 WeakPolarHBondContact O-CB 3.48Å; R252-C255 PolarHBondContact O-N 3.09Å; C255-S257 PolarHBondContact SG-OG 3.3Å
256N81.1Confident83.2Confident113 Ų11362.9 Ų62.960%0.60430%0.297SS*.  trans-93.516.4179.4-67.1-17.1000113.2V258 Q259 A260N256-V258 VanDerWaalsContact C-N 3.27Å; N256-V258 PolarHBondContact O-N 3.15Å; N256-Q259 WeakPolarHBondContact O-CB 3.47Å; N256-Q259 PolarHBondContact O-N 2.74Å; N256-A260 PolarHBondContact O-N 3.29Å
257S81.7Confident83.3Confident1 Ų161.8 Ų61.81%0.00729%0.291CS..Hα-helixtrans-58.5-36.4-174.6-50.70000113.6Y198 E203 C255 Q259 A260 L261Y198-S257 VanDerWaalsContact CE1-OG 3.31Å; Y198-S257 WeakPolarHBondContact CE1-OG 3.3Å; Y198-S257 PolarHBondContact OH-OG 3.17Å; E203-S257 WeakPolarHBondContact OE1-CA 3.37Å; E203-S257 WeakPolarHBondContact OE2-CB 3.2Å; E203-S257 PolarHBondContact OE2-OG 2.89Å; C255-S257 PolarHBondContact SG-OG 3.3Å; S257-Q259 VanDerWaalsContact C-N 3.34Å; S257-A260 PolarHBondContact O-N 3.31Å; S257-L261 WeakPolarHBondContact O-CB 3.31Å; S257-L261 PolarHBondContact O-N 3.18Å
258V86.6Confident83.5Confident28 Ų2856 Ų5617%0.1727%0.27CS..Hα-helixtrans-64.1-43.2177.11770000110.1A245 L246 L249 T251 N256 L261 M262A245-V258 HydrophobicContact CB-CB 4.41Å; A245-V258 HydrophobicContact CB-CG1 3.87Å; A245-V258 HydrophobicContact CB-CG2 4.18Å; L246-V258 HydrophobicContact CD2-CG1 4.48Å; L249-V258 HydrophobicContact CB-CG2 4.24Å; T251-V258 HydrophobicContact CG2-CG2 4.45Å; N256-V258 VanDerWaalsContact C-N 3.27Å; N256-V258 PolarHBondContact O-N 3.15Å; V258-L261 PolarHBondContact O-N 3.41Å; V258-M262 VanDerWaalsContact O-CG 3.3Å; V258-M262 WeakPolarHBondContact O-CG 3.44Å; V258-M262 PolarHBondContact O-N 3.35Å
259Q86.8Confident83.6Confident111 Ų11156 Ų5652%0.51927%0.27SS..Hα-helixtrans-65.5-44.5176.4-175179.3-16.700111.3N256 S257 L261 M262 E263N256-Q259 WeakPolarHBondContact O-CB 3.47Å; N256-Q259 PolarHBondContact O-N 2.74Å; S257-Q259 VanDerWaalsContact C-N 3.34Å; Q259-L261 VanDerWaalsContact C-N 3.3Å; Q259-L261 PolarHBondContact O-N 3.38Å; Q259-M262 PolarHBondContact O-N 3.02Å; Q259-M262 VanDerWaalsContact O-N 3.12Å; Q259-E263 PolarHBondContact NE2-OE1 3.48Å; Q259-E263 WeakPolarHBondContact O-CG 3.46Å; Q259-E263 PolarHBondContact O-N 3.13Å
260A87.9Confident83.7Confident31 Ų3156 Ų5626%0.25627%0.27SS..Hα-helixtrans-59.9-39.8177.500000112.2N256 S257 E263 C264N256-A260 PolarHBondContact O-N 3.29Å; S257-A260 PolarHBondContact O-N 3.31Å; A260-E263 PolarHBondContact O-N 3.28Å; A260-C264 WeakPolarHBondContact O-CB 3.34Å; A260-C264 PolarHBondContact O-N 2.88Å
261L90.3Very high84Confident0 Ų057.2 Ų57.20%028%0.278CS..Hα-helixtrans-65.2-43.8173.2178.569.6000112.2Y206 L207 T210 A245 L249 S257 V258 Q259 E263 C264 C265Y206-L261 HydrophobicContact CD1-CD1 3.85Å; Y206-L261 HydrophobicContact CD1-CD2 4.19Å; Y206-L261 HydrophobicContact CE1-CD1 3.83Å; Y206-L261 HydrophobicContact CE1-CD2 3.59Å; Y206-L261 HydrophobicContact CE1-CG 4.38Å; L207-L261 HydrophobicContact CD2-CB 3.76Å; L207-L261 HydrophobicContact CD2-CD1 3.69Å; L207-L261 HydrophobicContact CD2-CG 4.34Å; T210-L261 HydrophobicContact CG2-CD1 3.92Å; A245-L261 HydrophobicContact CB-CD2 3.54Å; L249-L261 HydrophobicContact CD1-CB 3.87Å; L249-L261 HydrophobicContact CD1-CD2 3.68Å; L249-L261 HydrophobicContact CD1-CG 4.37Å; S257-L261 WeakPolarHBondContact O-CB 3.31Å; S257-L261 PolarHBondContact O-N 3.18Å; V258-L261 PolarHBondContact O-N 3.41Å; Q259-L261 VanDerWaalsContact C-N 3.3Å; Q259-L261 PolarHBondContact O-N 3.38Å; L261-E263 VanDerWaalsContact C-N 3.33Å; L261-E263 PolarHBondContact O-N 2.97Å; L261-C264 WeakPolarHBondContact O-CB 3.39Å; L261-C264 PolarHBondContact O-N 3.36Å; L261-C265 WeakPolarHBondContact O-CB 3.35Å; L261-C265 PolarHBondContact O-N 3.35Å; L261-C265 PolarHBondContact O-SG 3.12Å
262M91.1Very high84.4Confident25 Ų2556.9 Ų56.912%0.12328%0.28CS..Hα-helixtrans-63.3-41.6177.8-69.9-51.4-65.200111.3L238 E242 V258 Q259 C265 V266L238-M262 HydrophobicContact CB-CE 4.15Å; L238-M262 HydrophobicContact CD2-CE 4.08Å; L238-M262 WeakPolarHBondContact O-CE 3.46Å; E242-M262 HydrophobicContact CB-CE 4.05Å; E242-M262 HydrophobicContact CB-SD 3.73Å; E242-M262 HydrophobicContact CG-SD 4.32Å; V258-M262 VanDerWaalsContact O-CG 3.3Å; V258-M262 WeakPolarHBondContact O-CG 3.44Å; V258-M262 PolarHBondContact O-N 3.35Å; Q259-M262 PolarHBondContact O-N 3.02Å; Q259-M262 VanDerWaalsContact O-N 3.12Å; M262-C265 PolarHBondContact O-N 3.37Å; M262-V266 WeakPolarHBondContact O-CB 3.16Å; M262-V266 WeakPolarHBondContact O-CG2 3.16Å; M262-V266 PolarHBondContact O-N 3Å
263E89.6Confident84.9Confident103 Ų10353.2 Ų53.248%0.48127%0.266SS..Hα-helixtrans-61.5-44.1173.7-72.9175-165.900111.7Q259 A260 L261 C265 V266 N267Q259-E263 PolarHBondContact NE2-OE1 3.48Å; Q259-E263 WeakPolarHBondContact O-CG 3.46Å; Q259-E263 PolarHBondContact O-N 3.13Å; A260-E263 PolarHBondContact O-N 3.28Å; L261-E263 VanDerWaalsContact C-N 3.33Å; L261-E263 PolarHBondContact O-N 2.97Å; E263-C265 PolarHBondContact O-N 3.08Å; E263-V266 PolarHBondContact O-N 3.5Å; E263-N267 WeakPolarHBondContact O-CB 3.21Å; E263-N267 VanDerWaalsContact O-CG 3.26Å; E263-N267 PolarHBondContact O-N 3.29Å; E263-N267 PolarHBondContact O-ND2 3.5Å
264C90.1Very high86.2Confident21 Ų2145 Ų4514%0.14224%0.238CC..Hα-helixtrans-59.9-45.6174-179.50000112.1L207 A260 L261 N267 A268L207-C264 HydrophobicContact CD2-CB 3.97Å; A260-C264 WeakPolarHBondContact O-CB 3.34Å; A260-C264 PolarHBondContact O-N 2.88Å; L261-C264 WeakPolarHBondContact O-CB 3.39Å; L261-C264 PolarHBondContact O-N 3.36Å; C264-N267 PolarHBondContact O-N 2.75Å; C264-A268 WeakPolarHBondContact O-CB 3.14Å; C264-A268 PolarHBondContact O-N 3.29Å
265C90.3Very high87.4Confident1 Ų143.5 Ų43.51%0.00723%0.231CC..Hα-helixtrans-65.8-42.7178.4-66.40000111.6T210 L238 L261 M262 E263 N267 A268 L269T210-C265 VanDerWaalsContact CG2-SG 3.51Å; L238-C265 HydrophobicContact CD2-CB 3.61Å; L261-C265 WeakPolarHBondContact O-CB 3.35Å; L261-C265 PolarHBondContact O-N 3.35Å; L261-C265 PolarHBondContact O-SG 3.12Å; M262-C265 PolarHBondContact O-N 3.37Å; E263-C265 PolarHBondContact O-N 3.08Å; C265-N267 VanDerWaalsContact C-N 3.29Å; C265-N267 PolarHBondContact O-N 3Å; C265-A268 PolarHBondContact O-N 3.19Å; C265-L269 VanDerWaalsContact O-CB 3.25Å; C265-L269 WeakPolarHBondContact O-CB 3.16Å; C265-L269 PolarHBondContact O-N 3.11Å
266V90.8Very high88.3Confident9 Ų946 Ų466%0.05525%0.246CC..Hα-helixtrans-61.3-40.7175169.30000110.1L238 M262 E263 V270 T271 K302 V303L238-V266 HydrophobicContact CD1-CG2 4.29Å; L238-V266 HydrophobicContact CD2-CG2 3.9Å; M262-V266 WeakPolarHBondContact O-CB 3.16Å; M262-V266 WeakPolarHBondContact O-CG2 3.16Å; M262-V266 PolarHBondContact O-N 3Å; E263-V266 PolarHBondContact O-N 3.5Å; V266-V270 HydrophobicContact CG1-CB 4.29Å; V266-V270 CarbonylContact O-C 3.58Å; V266-V270 VanDerWaalsContact O-CA 3.31Å; V266-V270 WeakPolarHBondContact O-CA 3.28Å; V266-V270 VanDerWaalsContact O-CB 3.3Å; V266-V270 WeakPolarHBondContact O-CB 3.39Å; V266-V270 PolarHBondContact O-N 2.82Å; V266-T271 PolarHBondContact O-N 3.05Å; V266-T271 PolarHBondContact O-OG1 2.84Å; V266-K302 HydrophobicContact CG1-CB 4.1Å; V266-K302 HydrophobicContact CG2-CB 4.01Å; V266-K302 HydrophobicContact CG2-CD 4.2Å; V266-V303 HydrophobicContact CG1-CG2 3.7Å
267N89.6Confident88.6Confident78 Ų7840.7 Ų40.742%0.41722%0.217SC..Hα-helixtrans-64.9-44.2176.7-75.5-29.4000112.9E263 C264 C265 T271 S272E263-N267 WeakPolarHBondContact O-CB 3.21Å; E263-N267 VanDerWaalsContact O-CG 3.26Å; E263-N267 PolarHBondContact O-N 3.29Å; E263-N267 PolarHBondContact O-ND2 3.5Å; C264-N267 PolarHBondContact O-N 2.75Å; C265-N267 VanDerWaalsContact C-N 3.29Å; C265-N267 PolarHBondContact O-N 3Å; N267-T271 WeakPolarHBondContact CA-OG1 3.29Å; N267-T271 PolarHBondContact OD1-OG1 2.88Å; N267-S272 PolarHBondContact O-N 3.11Å; N267-S272 VanDerWaalsContact O-N 3.13Å; N267-S272 PolarHBondContact O-OG 3.2Å
268A89.8Confident88.9Confident2 Ų241.6 Ų41.62%0.01722%0.222CC..Hα-helixtrans-70.8-41.4-18000000113.2E211 C264 C265E211-A268 HydrophobicContact CG-CB 4.23Å; C264-A268 WeakPolarHBondContact O-CB 3.14Å; C264-A268 PolarHBondContact O-N 3.29Å; C265-A268 PolarHBondContact O-N 3.19Å
269L88Confident89.1Confident0 Ų043.8 Ų43.80%024%0.243CC..Hα-helixtrans-93.5-34.1-173.8-72170.3000113.7Y214 A218 Y230 K237 L238 C265 F273Y214-L269 HydrophobicContact CD1-CD1 4.04Å; Y214-L269 HydrophobicContact CD1-CD2 3.58Å; Y214-L269 HydrophobicContact CD1-CG 4.08Å; Y214-L269 HydrophobicContact CD2-CD1 4.31Å; Y214-L269 HydrophobicContact CD2-CG 4.5Å; Y214-L269 HydrophobicContact CE1-CD1 4.2Å; Y214-L269 HydrophobicContact CE1-CD2 4.35Å; Y214-L269 HydrophobicContact CE2-CD1 4.49Å; Y214-L269 HydrophobicContact CG-CD1 4.09Å; Y214-L269 HydrophobicContact CG-CD2 3.85Å; Y214-L269 HydrophobicContact CG-CG 3.95Å; A218-L269 HydrophobicContact CB-CD2 3.99Å; Y230-L269 WeakPolarHBondContact CE1-O 3.34Å; Y230-L269 PolarHBondContact OH-O 3.3Å; K237-L269 HydrophobicContact CB-CD1 4.13Å; L238-L269 HydrophobicContact CD2-CD1 4.23Å; L238-L269 HydrophobicContact CG-CD1 4.3Å; C265-L269 VanDerWaalsContact O-CB 3.25Å; C265-L269 WeakPolarHBondContact O-CB 3.16Å; C265-L269 PolarHBondContact O-N 3.11Å; L269-F273 WeakPolarHBondContact O-CD2 3.29Å
270V88.3Confident89.2Confident1 Ų141.9 Ų41.91%0.00623%0.234CC..THydrogen-bonded Turntrans-112.9-56.7-170-168.20000110.6L238 V266 S272 F273 K274 I277 L299 M300 V303L238-V270 HydrophobicContact CD1-CG2 4.04Å; V266-V270 HydrophobicContact CG1-CB 4.29Å; V266-V270 CarbonylContact O-C 3.58Å; V266-V270 VanDerWaalsContact O-CA 3.31Å; V266-V270 WeakPolarHBondContact O-CA 3.28Å; V266-V270 VanDerWaalsContact O-CB 3.3Å; V266-V270 WeakPolarHBondContact O-CB 3.39Å; V266-V270 PolarHBondContact O-N 2.82Å; V270-S272 VanDerWaalsContact C-N 3.3Å; V270-S272 PolarHBondContact O-N 2.9Å; V270-F273 CarbonylContact O-C 3.48Å; V270-F273 PolarHBondContact O-N 2.98Å; V270-K274 PolarHBondContact O-N 3.47Å; V270-I277 HydrophobicContact CG1-CD1 4.48Å; V270-L299 HydrophobicContact CG1-CB 4.14Å; V270-L299 HydrophobicContact CG2-CD2 4.16Å; V270-M300 HydrophobicContact CG1-CE 3.4Å; V270-V303 HydrophobicContact CB-CG2 3.98Å; V270-V303 HydrophobicContact CG1-CG2 3.59Å
271T88.4Confident89.2Confident37 Ų3740.4 Ų40.423%0.22722%0.222CC..G310 helixtrans-59.4-40.2-175.9-51.40000112.2V266 N267 F273 K274 V303V266-T271 PolarHBondContact O-N 3.05Å; V266-T271 PolarHBondContact O-OG1 2.84Å; N267-T271 WeakPolarHBondContact CA-OG1 3.29Å; N267-T271 PolarHBondContact OD1-OG1 2.88Å; T271-F273 PolarHBondContact O-N 2.87Å; T271-K274 HydrophobicContact CG2-CD 4.44Å; T271-K274 WeakPolarHBondContact O-CB 3.48Å; T271-K274 VanDerWaalsContact O-CG 3.3Å; T271-K274 WeakPolarHBondContact O-CG 3.44Å; T271-K274 PolarHBondContact O-N 2.89Å; T271-V303 HydrophobicContact CG2-CG1 4.3Å
272S87.4Confident89.2Confident75 Ų7542.4 Ų42.452%0.52424%0.235SC..G310 helixtrans-63.4-25.6179-62.20000113.8N267 V270N267-S272 PolarHBondContact O-N 3.11Å; N267-S272 VanDerWaalsContact O-N 3.13Å; N267-S272 PolarHBondContact O-OG 3.2Å; V270-S272 VanDerWaalsContact C-N 3.3Å; V270-S272 PolarHBondContact O-N 2.9Å
273F88.4Confident89.1Confident31 Ų3142.1 Ų42.114%0.13624%0.238CC..G310 helixtrans-115.613-178.1-57.2-80.5000112.7A218 P219 L222 Y230 L269 V270 T271 E275 T276 I277A218-F273 HydrophobicContact CB-CE2 3.68Å; A218-F273 HydrophobicContact CB-CZ 3.99Å; P219-F273 HydrophobicContact CB-CE1 4.45Å; P219-F273 HydrophobicContact CB-CZ 4.3Å; P219-F273 HydrophobicContact CG-CE1 4.44Å; P219-F273 HydrophobicContact CG-CZ 3.87Å; L222-F273 HydrophobicContact CD2-CD1 3.41Å; L222-F273 VanDerWaalsContact CD2-CD1 3.41Å; L222-F273 HydrophobicContact CD2-CE1 3.83Å; L222-F273 HydrophobicContact CD2-CG 4.16Å; Y230-F273 HydrophobicContact CE1-CB 4.27Å; Y230-F273 HydrophobicContact CE1-CD2 4.16Å; Y230-F273 HydrophobicContact CE1-CG 4.33Å; Y230-F273 AromaticContact CZ-CD2 3.84Å; Y230-F273 WeakPolarHBondContact OH-CD2 3.49Å; Y230-F273 WeakPolarHBondContact OH-CE2 3.48Å; L269-F273 WeakPolarHBondContact O-CD2 3.29Å; V270-F273 CarbonylContact O-C 3.48Å; V270-F273 PolarHBondContact O-N 2.98Å; T271-F273 PolarHBondContact O-N 2.87Å; F273-E275 VanDerWaalsContact C-N 3.28Å; F273-E275 PolarHBondContact O-N 3.42Å; F273-T276 PolarHBondContact O-N 2.98Å; F273-I277 HydrophobicContact CB-CD1 4.32Å; F273-I277 WeakPolarHBondContact O-CG1 3.43Å; F273-I277 PolarHBondContact O-N 3.24Å
274K88.8Confident89Confident83 Ų8337.2 Ų37.236%0.36122%0.215SC..Hα-helixtrans-55.3-42.5-173.572.2-175.4-177.2174.30112.3V270 T271 T276 I277 L278V270-K274 PolarHBondContact O-N 3.47Å; T271-K274 HydrophobicContact CG2-CD 4.44Å; T271-K274 WeakPolarHBondContact O-CB 3.48Å; T271-K274 VanDerWaalsContact O-CG 3.3Å; T271-K274 WeakPolarHBondContact O-CG 3.44Å; T271-K274 PolarHBondContact O-N 2.89Å; K274-T276 PolarHBondContact O-N 3.43Å; K274-I277 PolarHBondContact O-N 3.16Å; K274-L278 VanDerWaalsContact O-CB 3.31Å; K274-L278 WeakPolarHBondContact O-CB 3.03Å; K274-L278 WeakPolarHBondContact O-CG 3.38Å; K274-L278 PolarHBondContact O-N 3.14Å
275E89.1Confident89Confident149 Ų14936.2 Ų36.270%0.69621%0.209SC*.Hα-helixtrans-67.1-39.7-176.3-64.3-176.8177.700111.4F273 L278 A279F273-E275 VanDerWaalsContact C-N 3.28Å; F273-E275 PolarHBondContact O-N 3.42Å; E275-L278 PolarHBondContact O-N 3.02Å; E275-A279 WeakPolarHBondContact O-CB 3.46Å; E275-A279 PolarHBondContact O-N 3.37Å
276T89.3Confident88.9Confident67 Ų6742.9 Ų42.941%0.41124%0.238SC..Hα-helixtrans-68.3-37.7176.4-43.80000111.8V227 F273 K274V227-T276 HydrophobicContact CG2-CG2 3.89Å; F273-T276 PolarHBondContact O-N 2.98Å; K274-T276 PolarHBondContact O-N 3.43Å
277I88.6Confident88.8Confident1 Ų148.7 Ų48.71%0.00526%0.258CS..Hα-helixtrans-67.9-46.5176.1-63165.1000110.4V227 Y230 M231 V270 F273 K274 A279 E280 M296 M300V227-I277 HydrophobicContact CG1-CB 4.39Å; V227-I277 HydrophobicContact CG1-CG1 4.12Å; Y230-I277 HydrophobicContact CD1-CD1 4.47Å; Y230-I277 HydrophobicContact CE1-CD1 4.33Å; M231-I277 HydrophobicContact CG-CG2 4.14Å; M231-I277 HydrophobicContact SD-CG2 3.69Å; V270-I277 HydrophobicContact CG1-CD1 4.48Å; F273-I277 HydrophobicContact CB-CD1 4.32Å; F273-I277 WeakPolarHBondContact O-CG1 3.43Å; F273-I277 PolarHBondContact O-N 3.24Å; K274-I277 PolarHBondContact O-N 3.16Å; I277-A279 VanDerWaalsContact C-N 3.3Å; I277-A279 PolarHBondContact O-N 3.15Å; I277-E280 PolarHBondContact O-N 2.99Å; I277-M296 HydrophobicContact CG2-CG 3.84Å; I277-M296 HydrophobicContact CG2-SD 4.05Å; I277-M300 HydrophobicContact CB-CE 4.08Å; I277-M300 HydrophobicContact CD1-CE 3.83Å; I277-M300 HydrophobicContact CG2-CE 3.81Å
278L88.4Confident88.6Confident21 Ų2148.9 Ų48.911%0.1126%0.259CS..Hα-helixtrans-65.9-30.1-179.6-69.9170.1000112.6K274 E275 E280 C281 P282 M300 P309 M310K274-L278 VanDerWaalsContact O-CB 3.31Å; K274-L278 WeakPolarHBondContact O-CB 3.03Å; K274-L278 WeakPolarHBondContact O-CG 3.38Å; K274-L278 PolarHBondContact O-N 3.14Å; E275-L278 PolarHBondContact O-N 3.02Å; L278-E280 PolarHBondContact O-N 3.21Å; L278-C281 WeakPolarHBondContact O-CB 3.45Å; L278-C281 PolarHBondContact O-N 3.3Å; L278-P282 WeakPolarHBondContact O-CD 3.48Å; L278-M300 HydrophobicContact CD2-CG 4.27Å; L278-M300 HydrophobicContact CD2-SD 4.2Å; L278-M300 HydrophobicContact CG-SD 4.33Å; L278-P309 HydrophobicContact CD1-CB 3.93Å; L278-P309 HydrophobicContact CD1-CG 3.8Å; L278-P309 HydrophobicContact CD2-CB 4.2Å; L278-M310 HydrophobicContact CD2-CG 3.58Å; L278-M310 HydrophobicContact CD2-SD 4.38Å
279A89.8Confident88.6Confident74 Ų7450.8 Ų50.861%0.61227%0.268SS*.Hα-helixtrans-60.3-26.3175.500000113.7E275 I277E275-A279 WeakPolarHBondContact O-CB 3.46Å; E275-A279 PolarHBondContact O-N 3.37Å; I277-A279 VanDerWaalsContact C-N 3.3Å; I277-A279 PolarHBondContact O-N 3.15Å
280E88.6Confident88.7Confident70 Ų7052.2 Ų52.233%0.32728%0.277SS..Hα-helixtrans-83.9-16.4176.6-72.1-67.7138.400113.2V227 I277 L278 G283 M284V227-E280 HydrophobicContact CB-CG 4.02Å; V227-E280 HydrophobicContact CG1-CG 4Å; V227-E280 HydrophobicContact CG2-CG 4.11Å; I277-E280 PolarHBondContact O-N 2.99Å; L278-E280 PolarHBondContact O-N 3.21Å; E280-G283 PolarHBondContact O-N 2.98Å; E280-G283 VanDerWaalsContact O-N 3.13Å; E280-M284 HydrophobicContact CB-CE 3.83Å; E280-M284 WeakPolarHBondContact O-CG 3.29Å; E280-M284 PolarHBondContact O-N 3.43Å
281C89.4Confident88.8Confident0 Ų060 Ų600%031%0.313CS..Hα-helixtrans-54.8-50.8-176.9175.10000112.8L278 G283 M284 I285 M296 D313L278-C281 WeakPolarHBondContact O-CB 3.45Å; L278-C281 PolarHBondContact O-N 3.3Å; C281-G283 VanDerWaalsContact C-N 3.26Å; C281-G283 PolarHBondContact O-N 2.98Å; C281-M284 PolarHBondContact O-N 3.23Å; C281-I285 VanDerWaalsContact O-CG1 3.31Å; C281-I285 WeakPolarHBondContact O-CG1 3.47Å; C281-I285 PolarHBondContact O-N 3Å; C281-I285 VanDerWaalsContact SG-CD1 3.58Å; C281-M296 HydrophobicContact CB-CE 3.35Å; C281-M296 HydrophobicContact CB-SD 3.88Å; C281-M296 WeakPolarHBondContact SG-CE 3.48Å; C281-D313 PolarHBondContact SG-OD2 3.05Å
282P89.1Confident88.8Confident42 Ų4261.1 Ų61.127%0.27332%0.315SS..Hα-helixtrans-60-35.1178.8-23.333.3000113.4L278 K286 D313L278-P282 WeakPolarHBondContact O-CD 3.48Å; P282-K286 WeakPolarHBondContact O-CB 3.39Å; P282-K286 VanDerWaalsContact O-CG 3.28Å; P282-K286 WeakPolarHBondContact O-CG 3.27Å; P282-K286 PolarHBondContact O-N 2.86Å; P282-K286 VanDerWaalsContact O-N 3.1Å; P282-D313 HydrophobicContact CG-CB 4.27Å
283G88.8Confident89Confident19 Ų1957.5 Ų57.520%0.19629%0.29CS..Hα-helixtrans-69.3-42.8178.500000112.3E280 C281 K286 R287E280-G283 PolarHBondContact O-N 2.98Å; E280-G283 VanDerWaalsContact O-N 3.13Å; C281-G283 VanDerWaalsContact C-N 3.26Å; C281-G283 PolarHBondContact O-N 2.98Å; G283-K286 PolarHBondContact O-N 3.45Å; G283-R287 WeakPolarHBondContact O-CG 3.41Å; G283-R287 PolarHBondContact O-N 3.41Å; G283-R287 VanDerWaalsContact O-N 3.14Å
284M88.4Confident89.2Confident0 Ų058.8 Ų58.80%030%0.296CS..Hα-helixtrans-66.7-39.9177.3-68.3176.4-176.700112.2Q228 M231 E280 C281 R287 N288 E289 K292 L293 M296Q228-M284 HydrophobicContact CG-CE 3.71Å; M231-M284 HydrophobicContact CE-CE 3.49Å; M231-M284 VanDerWaalsContact CE-CE 3.49Å; M231-M284 HydrophobicContact CE-SD 4.16Å; E280-M284 HydrophobicContact CB-CE 3.83Å; E280-M284 WeakPolarHBondContact O-CG 3.29Å; E280-M284 PolarHBondContact O-N 3.43Å; C281-M284 PolarHBondContact O-N 3.23Å; M284-R287 PolarHBondContact O-N 3.44Å; M284-N288 PolarHBondContact O-N 3.34Å; M284-E289 HydrophobicContact CB-CB 4.44Å; M284-E289 PolarHBondContact O-N 2.9Å; M284-E289 VanDerWaalsContact O-N 3.08Å; M284-K292 HydrophobicContact SD-CB 4.11Å; M284-L293 HydrophobicContact CB-CD2 3.57Å; M284-L293 HydrophobicContact CB-CG 3.94Å; M284-M296 HydrophobicContact SD-SD 4.32Å
285I89.5Confident89.3Confident0 Ų056 Ų560%029%0.285CS..Hα-helixtrans-60.1-50.4174-67.4172000109.8C281 R287 N288 L293 D313 L314 H317 L354C281-I285 VanDerWaalsContact O-CG1 3.31Å; C281-I285 WeakPolarHBondContact O-CG1 3.47Å; C281-I285 PolarHBondContact O-N 3Å; C281-I285 VanDerWaalsContact SG-CD1 3.58Å; I285-R287 VanDerWaalsContact C-N 3.26Å; I285-R287 PolarHBondContact O-N 3.38Å; I285-N288 PolarHBondContact O-N 2.96Å; I285-N288 VanDerWaalsContact O-N 3.12Å; I285-L293 HydrophobicContact CG1-CD1 4.18Å; I285-L293 HydrophobicContact CG1-CD2 3.82Å; I285-D313 HydrophobicContact CD1-CB 4.07Å; I285-L314 HydrophobicContact CD1-CB 4.19Å; I285-L314 HydrophobicContact CD1-CD1 4.48Å; I285-L314 HydrophobicContact CG2-CD1 4.17Å; I285-H317 HydrophobicContact CG2-CB 3.86Å; I285-H317 WeakPolarHBondContact CG2-CD2 3.14Å; I285-L354 HydrophobicContact CG2-CD2 4.18Å
286K87.4Confident89.4Confident142 Ų14248.9 Ų48.962%0.61725%0.252SS*.Hα-helixtrans-59.3-34.1179.7-77.5173.5-178.2-179.10113.6P282 G283 H317P282-K286 WeakPolarHBondContact O-CB 3.39Å; P282-K286 VanDerWaalsContact O-CG 3.28Å; P282-K286 WeakPolarHBondContact O-CG 3.27Å; P282-K286 PolarHBondContact O-N 2.86Å; P282-K286 VanDerWaalsContact O-N 3.1Å; G283-K286 PolarHBondContact O-N 3.45Å; K286-H317 VanDerWaalsContact CG-CE1 3.47Å; K286-H317 WeakPolarHBondContact CG-CE1 3.26Å; K286-H317 WeakPolarHBondContact CG-ND1 3.24Å
287R88.9Confident89.5Confident130 Ų13046.5 Ų46.549%0.49124%0.236SC..THydrogen-bonded Turntrans-88.8-0-179.6-68.8-174.9-61.4-96.2-1.9114G283 M284 I285 E289G283-R287 WeakPolarHBondContact O-CG 3.41Å; G283-R287 PolarHBondContact O-N 3.41Å; G283-R287 VanDerWaalsContact O-N 3.14Å; M284-R287 PolarHBondContact O-N 3.44Å; I285-R287 VanDerWaalsContact C-N 3.26Å; I285-R287 PolarHBondContact O-N 3.38Å; R287-E289 VanDerWaalsContact C-N 3.3Å; R287-E289 HydrophobicContact CB-CG 3.83Å; R287-E289 IonicContact CZ-OE2 2.81Å; R287-E289 IonicContact NE-OE1 3.94Å; R287-E289 IonicContact NE-OE2 2.93Å; R287-E289 PolarHBondContact NE-OE2 2.91Å; R287-E289 IonicContact NH2-OE2 3.79Å; R287-E289 PolarHBondContact NH2-OE2 3.47Å; R287-E289 PolarHBondContact O-N 3.48Å
288N87.1Confident89.6Confident82 Ų8248.3 Ų48.344%0.43925%0.248SC..THydrogen-bonded Turntrans54.740.3-174.4-63.4-42.9000113.6M284 I285 T290M284-N288 PolarHBondContact O-N 3.34Å; I285-N288 PolarHBondContact O-N 2.96Å; I285-N288 VanDerWaalsContact O-N 3.12Å; N288-T290 VanDerWaalsContact C-N 3.28Å; N288-T290 PolarHBondContact O-N 3.39Å
289E89.9Confident89.6Confident42 Ų4247.3 Ų47.320%0.19624%0.243CC..  trans-81.468.7179.5-64.1-179120.200111.4M284 R287 E291 K292 L293M284-E289 HydrophobicContact CB-CB 4.44Å; M284-E289 PolarHBondContact O-N 2.9Å; M284-E289 VanDerWaalsContact O-N 3.08Å; R287-E289 VanDerWaalsContact C-N 3.3Å; R287-E289 HydrophobicContact CB-CG 3.83Å; R287-E289 IonicContact CZ-OE2 2.81Å; R287-E289 IonicContact NE-OE1 3.94Å; R287-E289 IonicContact NE-OE2 2.93Å; R287-E289 PolarHBondContact NE-OE2 2.91Å; R287-E289 IonicContact NH2-OE2 3.79Å; R287-E289 PolarHBondContact NH2-OE2 3.47Å; R287-E289 PolarHBondContact O-N 3.48Å; E289-E291 PolarHBondContact O-N 3.47Å; E289-K292 HydrophobicContact CB-CB 4.25Å; E289-K292 HydrophobicContact CB-CD 4.06Å; E289-K292 HydrophobicContact CB-CG 4.33Å; E289-K292 HydrophobicContact CG-CD 4.44Å; E289-K292 PolarHBondContact O-N 3.04Å; E289-K292 VanDerWaalsContact O-N 3.13Å; E289-K292 IonicContact OE1-NZ 3.53Å; E289-K292 PolarHBondContact OE1-NZ 3.01Å; E289-L293 WeakPolarHBondContact O-CG 3.45Å; E289-L293 PolarHBondContact O-N 3.39Å
290T90Very high89.7Confident31 Ų3143.8 Ų43.819%0.1921%0.214CC..Hα-helixtrans-57.1-43.6-169.850.50000114.4N288 K292 L293 H294 L354 E357 A358N288-T290 VanDerWaalsContact C-N 3.28Å; N288-T290 PolarHBondContact O-N 3.39Å; T290-K292 VanDerWaalsContact C-N 3.31Å; T290-K292 PolarHBondContact O-N 2.93Å; T290-L293 PolarHBondContact O-N 2.91Å; T290-H294 WeakPolarHBondContact O-CB 3.18Å; T290-H294 PolarHBondContact O-N 3.36Å; T290-L354 HydrophobicContact CG2-CD1 3.98Å; T290-E357 HydrophobicContact CG2-CB 3.71Å; T290-A358 HydrophobicContact CG2-CB 4.38Å
291E89.6Confident89.7Confident164 Ų16444.2 Ų44.277%0.76622%0.219SC*.Hα-helixtrans-61.4-38.9177.9-64.3-175.7170.700112.7E289 H294 L295E289-E291 PolarHBondContact O-N 3.47Å; E291-H294 PolarHBondContact O-N 3.47Å; E291-L295 PolarHBondContact O-N 2.85Å; E291-L295 VanDerWaalsContact O-N 3.12Å
292K89Confident89.6Confident60 Ų6048.7 Ų48.726%0.26124%0.238SC..Hα-helixtrans-74.3-39.7-179.1-58.7-178.4-169.7173.70110.8Q228 M284 E289 T290 H294 L295 M296Q228-K292 VanDerWaalsContact OE1-CE 3.31Å; M284-K292 HydrophobicContact SD-CB 4.11Å; E289-K292 HydrophobicContact CB-CB 4.25Å; E289-K292 HydrophobicContact CB-CD 4.06Å; E289-K292 HydrophobicContact CB-CG 4.33Å; E289-K292 HydrophobicContact CG-CD 4.44Å; E289-K292 PolarHBondContact O-N 3.04Å; E289-K292 VanDerWaalsContact O-N 3.13Å; E289-K292 IonicContact OE1-NZ 3.53Å; E289-K292 PolarHBondContact OE1-NZ 3.01Å; T290-K292 VanDerWaalsContact C-N 3.31Å; T290-K292 PolarHBondContact O-N 2.93Å; K292-H294 VanDerWaalsContact C-N 3.3Å; K292-H294 PolarHBondContact O-N 3.14Å; K292-L295 PolarHBondContact O-N 2.96Å; K292-M296 WeakPolarHBondContact O-CB 3.32Å; K292-M296 PolarHBondContact O-N 3.36Å
293L90.9Very high89.5Confident0 Ų047.1 Ų47.10%023%0.228CC..Hα-helixtrans-63.1-38.1173.3-70.6170000111.7M284 I285 E289 T290 M296 F297 L354 A358 F359M284-L293 HydrophobicContact CB-CD2 3.57Å; M284-L293 HydrophobicContact CB-CG 3.94Å; I285-L293 HydrophobicContact CG1-CD1 4.18Å; I285-L293 HydrophobicContact CG1-CD2 3.82Å; E289-L293 WeakPolarHBondContact O-CG 3.45Å; E289-L293 PolarHBondContact O-N 3.39Å; T290-L293 PolarHBondContact O-N 2.91Å; L293-M296 HydrophobicContact CD2-CE 3.72Å; L293-M296 PolarHBondContact O-N 2.48Å; L293-F297 WeakPolarHBondContact O-CB 3.26Å; L293-F297 PolarHBondContact O-N 3.22Å; L293-L354 HydrophobicContact CD1-CD1 4.13Å; L293-A358 HydrophobicContact CB-CB 3.72Å; L293-A358 HydrophobicContact CD1-CB 4.05Å; L293-F359 HydrophobicContact CB-CE1 4.43Å; L293-F359 HydrophobicContact CB-CZ 4.46Å
294H91.8Very high89.2Confident57 Ų5751.3 Ų51.326%0.26425%0.251SS..Hα-helixtrans-63.5-44.5175.6-175.157.3000112.1T290 E291 K292 F297 S298 A358 Q360T290-H294 WeakPolarHBondContact O-CB 3.18Å; T290-H294 PolarHBondContact O-N 3.36Å; E291-H294 PolarHBondContact O-N 3.47Å; K292-H294 VanDerWaalsContact C-N 3.3Å; K292-H294 PolarHBondContact O-N 3.14Å; H294-F297 PolarHBondContact O-N 3Å; H294-S298 PolarHBondContact O-N 2.93Å; H294-A358 WeakPolarHBondContact CA-O 3.33Å; H294-A358 WeakPolarHBondContact CB-O 3.38Å; H294-A358 PolarHBondContact ND1-O 3.27Å; H294-Q360 PolarHBondContact CE1-NE2 2.98Å; H294-Q360 PolarHBondContact NE2-NE2 3.08Å
295L91.2Very high88.8Confident25 Ų2555 Ų5513%0.13128%0.277CS..Hα-helixtrans-61.3-45.1174.2-179.564.5000111.8M231 K232 D235 E291 K292 F297 S298 L299M231-L295 HydrophobicContact CB-CD2 3.75Å; M231-L295 HydrophobicContact CB-CG 4.16Å; K232-L295 HydrophobicContact CB-CD2 4.3Å; K232-L295 HydrophobicContact CG-CD2 3.51Å; D235-L295 HydrophobicContact CB-CD1 3.63Å; E291-L295 PolarHBondContact O-N 2.85Å; E291-L295 VanDerWaalsContact O-N 3.12Å; K292-L295 PolarHBondContact O-N 2.96Å; L295-F297 VanDerWaalsContact C-N 3.34Å; L295-F297 PolarHBondContact O-N 3.13Å; L295-S298 PolarHBondContact O-N 3.01Å; L295-L299 HydrophobicContact CG-CD1 4.42Å; L295-L299 WeakPolarHBondContact O-CG 3.01Å; L295-L299 PolarHBondContact O-N 3.36Å; L295-L299 VanDerWaalsContact O-N 3.09Å
296M91.2Very high88.6Confident0 Ų055.1 Ų55.10%028%0.279CS..Hα-helixtrans-61.7-42.6177-171.817373.400111.6M231 I277 C281 M284 K292 L293 L299 M300 M310M231-M296 HydrophobicContact SD-CB 3.72Å; M231-M296 HydrophobicContact SD-CG 3.94Å; M231-M296 HydrophobicContact SD-SD 4.48Å; I277-M296 HydrophobicContact CG2-CG 3.84Å; I277-M296 HydrophobicContact CG2-SD 4.05Å; C281-M296 HydrophobicContact CB-CE 3.35Å; C281-M296 HydrophobicContact CB-SD 3.88Å; C281-M296 WeakPolarHBondContact SG-CE 3.48Å; M284-M296 HydrophobicContact SD-SD 4.32Å; K292-M296 WeakPolarHBondContact O-CB 3.32Å; K292-M296 PolarHBondContact O-N 3.36Å; L293-M296 HydrophobicContact CD2-CE 3.72Å; L293-M296 PolarHBondContact O-N 2.48Å; M296-L299 PolarHBondContact O-N 2.94Å; M296-M300 HydrophobicContact CG-CG 4.28Å; M296-M300 WeakPolarHBondContact O-CB 3.47Å; M296-M300 VanDerWaalsContact O-CG 3.27Å; M296-M300 WeakPolarHBondContact O-CG 3.41Å; M296-M300 PolarHBondContact O-N 3.37Å; M296-M310 HydrophobicContact CE-CE 3.39Å; M296-M310 HydrophobicContact CE-CG 4.21Å; M296-M310 HydrophobicContact CE-SD 3.96Å; M296-M310 HydrophobicContact CG-CE 4.3Å; M296-M310 HydrophobicContact CG-SD 4.2Å
297F91.6Very high88.6Confident16 Ų1649 Ų497%0.0725%0.252CS..Hα-helixtrans-60.3-47.2174.9169-113.5000111.7L293 H294 L295 L299 M300 D301 I307 M310 F359 D362 F365L293-F297 WeakPolarHBondContact O-CB 3.26Å; L293-F297 PolarHBondContact O-N 3.22Å; H294-F297 PolarHBondContact O-N 3Å; L295-F297 VanDerWaalsContact C-N 3.34Å; L295-F297 PolarHBondContact O-N 3.13Å; F297-L299 VanDerWaalsContact C-N 3.26Å; F297-L299 PolarHBondContact O-N 3.29Å; F297-M300 PolarHBondContact O-N 2.96Å; F297-D301 HydrophobicContact CE2-CB 4.36Å; F297-D301 VanDerWaalsContact O-CB 3.32Å; F297-D301 WeakPolarHBondContact O-CB 3.06Å; F297-D301 PolarHBondContact O-N 3.24Å; F297-I307 HydrophobicContact CE2-CD1 4.09Å; F297-M310 HydrophobicContact CB-CE 4.09Å; F297-F359 HydrophobicContact CB-CD1 3.89Å; F297-F359 HydrophobicContact CB-CE1 4.2Å; F297-F359 HydrophobicContact CD2-CD1 4.23Å; F297-F359 HydrophobicContact CG-CD1 4.01Å; F297-D362 HydrophobicContact CZ-CB 4.09Å; F297-F365 AromaticContact CD2-CE2 3.61Å; F297-F365 HydrophobicContact CD2-CE2 3.61Å; F297-F365 HydrophobicContact CD2-CZ 4.11Å; F297-F365 HydrophobicContact CE2-CD2 4.32Å; F297-F365 AromaticContact CE2-CE2 3.63Å; F297-F365 HydrophobicContact CE2-CE2 3.63Å
298S90.4Very high88.6Confident39 Ų3948.6 Ų48.627%0.27326%0.256SS..Hα-helixtrans-60.4-35.3178.5-173.70000113H294 L295H294-S298 PolarHBondContact O-N 2.93Å; L295-S298 PolarHBondContact O-N 3.01Å
299L89.8Confident88.8Confident0 Ų047 Ų470%025%0.25CC..Hα-helixtrans-74.5-44.3175.3-67.9172.6000112.1M231 A234 D235 L238 V270 L295 M296 F297 K302M231-L299 HydrophobicContact CB-CD1 3.73Å; M231-L299 HydrophobicContact CG-CD1 3.94Å; A234-L299 HydrophobicContact CB-CD2 4.4Å; D235-L299 HydrophobicContact CB-CD2 4.09Å; L238-L299 HydrophobicContact CD1-CD2 3.83Å; V270-L299 HydrophobicContact CG1-CB 4.14Å; V270-L299 HydrophobicContact CG2-CD2 4.16Å; L295-L299 HydrophobicContact CG-CD1 4.42Å; L295-L299 WeakPolarHBondContact O-CG 3.01Å; L295-L299 PolarHBondContact O-N 3.36Å; L295-L299 VanDerWaalsContact O-N 3.09Å; M296-L299 PolarHBondContact O-N 2.94Å; F297-L299 VanDerWaalsContact C-N 3.26Å; F297-L299 PolarHBondContact O-N 3.29Å; L299-K302 PolarHBondContact O-N 3.4Å
300M90.4Very high88.8Confident0 Ų045 Ų450%024%0.241CC..Hα-helixtrans-74.4-25.5-177.1-68.7-59.1123.900113.3V270 I277 L278 M296 F297 K302 V303 I307 M310V270-M300 HydrophobicContact CG1-CE 3.4Å; I277-M300 HydrophobicContact CB-CE 4.08Å; I277-M300 HydrophobicContact CD1-CE 3.83Å; I277-M300 HydrophobicContact CG2-CE 3.81Å; L278-M300 HydrophobicContact CD2-CG 4.27Å; L278-M300 HydrophobicContact CD2-SD 4.2Å; L278-M300 HydrophobicContact CG-SD 4.33Å; M296-M300 HydrophobicContact CG-CG 4.28Å; M296-M300 WeakPolarHBondContact O-CB 3.47Å; M296-M300 VanDerWaalsContact O-CG 3.27Å; M296-M300 WeakPolarHBondContact O-CG 3.41Å; M296-M300 PolarHBondContact O-N 3.37Å; F297-M300 PolarHBondContact O-N 2.96Å; M300-K302 PolarHBondContact O-N 3.33Å; M300-V303 PolarHBondContact O-N 2.86Å; M300-V303 VanDerWaalsContact O-N 3.09Å; M300-V303 VanDerWaalsContact O-O 3.09Å; M300-I307 HydrophobicContact CB-CG1 4.38Å; M300-M310 HydrophobicContact CB-SD 3.75Å; M300-M310 HydrophobicContact CG-SD 3.71Å
301D90.3Very high88.8Confident79 Ų7944.8 Ų44.842%0.42224%0.238SC..Hα-helixtrans-67.1-25.3174.3-169.559.2000112.4F297 V303 I307 R364F297-D301 HydrophobicContact CE2-CB 4.36Å; F297-D301 VanDerWaalsContact O-CB 3.32Å; F297-D301 WeakPolarHBondContact O-CB 3.06Å; F297-D301 PolarHBondContact O-N 3.24Å; D301-V303 VanDerWaalsContact C-N 3.3Å; D301-I307 HydrophobicContact CB-CD1 3.74Å; D301-I307 HydrophobicContact CB-CG1 4.43Å; D301-I307 WeakPolarHBondContact OD1-CD1 3.48Å; D301-R364 IonicContact OD1-CZ 3.61Å; D301-R364 IonicContact OD1-NH1 3.42Å; D301-R364 PolarHBondContact OD1-NH1 3.49Å; D301-R364 IonicContact OD1-NH2 3.28Å; D301-R364 PolarHBondContact OD1-NH2 2.9Å
302K86.6Confident88.8Confident95 Ų9542.6 Ų42.641%0.41323%0.226SC..THydrogen-bonded Turntrans-77.4-15.1172.9-61.7170.8-174.8-89.40113L238 V266 L299 M300L238-K302 HydrophobicContact CD1-CD 4.39Å; V266-K302 HydrophobicContact CG1-CB 4.1Å; V266-K302 HydrophobicContact CG2-CB 4.01Å; V266-K302 HydrophobicContact CG2-CD 4.2Å; L299-K302 PolarHBondContact O-N 3.4Å; M300-K302 PolarHBondContact O-N 3.33Å
303V87.2Confident88.9Confident8 Ų841.3 Ų41.35%0.04822%0.222CC..SBendtrans-100.1128.6-177.7-179.70000109.9V266 V270 T271 M300 D301 S305 G306V266-V303 HydrophobicContact CG1-CG2 3.7Å; V270-V303 HydrophobicContact CB-CG2 3.98Å; V270-V303 HydrophobicContact CG1-CG2 3.59Å; T271-V303 HydrophobicContact CG2-CG1 4.3Å; M300-V303 PolarHBondContact O-N 2.86Å; M300-V303 VanDerWaalsContact O-N 3.09Å; M300-V303 VanDerWaalsContact O-O 3.09Å; D301-V303 VanDerWaalsContact C-N 3.3Å; V303-S305 PolarHBondContact O-N 3.5Å; V303-G306 PolarHBondContact O-N 3.05Å
304P82.1Confident88.8Confident107 Ų10741.3 Ų41.370%0.69522%0.222SC*.THydrogen-bonded Turntrans-55.4125.5173.2-24.233.6000111.3G306P304-G306 PolarHBondContact O-N 2.98Å; P304-G306 VanDerWaalsContact O-N 3.15Å
305S80.6Confident88.7Confident78 Ų7839.8 Ų39.855%0.54522%0.215SC..THydrogen-bonded Turntrans57.818.8-175.8-62.60000115.5V303 I307 E308 P309V303-S305 PolarHBondContact O-N 3.5Å; S305-I307 VanDerWaalsContact C-N 3.29Å; S305-I307 PolarHBondContact O-N 3.28Å; S305-E308 WeakPolarHBondContact CB-OE1 3.24Å; S305-E308 PolarHBondContact OG-OE1 3.37Å; S305-P309 WeakPolarHBondContact O-CD 3.36Å
306G84Confident88.6Confident3 Ų342.8 Ų42.83%0.03123%0.229CC..SBendtrans-69.1-25.8176.400000113.9V303 P304 P309V303-G306 PolarHBondContact O-N 3.05Å; P304-G306 PolarHBondContact O-N 2.98Å; P304-G306 VanDerWaalsContact O-N 3.15Å; G306-P309 WeakPolarHBondContact O-CD 3.24Å
307I88.8Confident88.5Confident12 Ų1244.2 Ų44.26%0.06224%0.235CC..Hα-helixtrans-86.8-26.3-174.8-58.8168000112.6F297 M300 D301 S305 M310 L311 R364 F365F297-I307 HydrophobicContact CE2-CD1 4.09Å; M300-I307 HydrophobicContact CB-CG1 4.38Å; D301-I307 HydrophobicContact CB-CD1 3.74Å; D301-I307 HydrophobicContact CB-CG1 4.43Å; D301-I307 WeakPolarHBondContact OD1-CD1 3.48Å; S305-I307 VanDerWaalsContact C-N 3.29Å; S305-I307 PolarHBondContact O-N 3.28Å; I307-M310 WeakPolarHBondContact O-CB 3.21Å; I307-M310 PolarHBondContact O-N 2.94Å; I307-L311 HydrophobicContact CG2-CD1 4.13Å; I307-L311 HydrophobicContact CG2-CD2 4.43Å; I307-L311 HydrophobicContact CG2-CG 3.95Å; I307-L311 WeakPolarHBondContact O-CG 3.31Å; I307-L311 PolarHBondContact O-N 2.85Å; I307-R364 VanDerWaalsContact CD1-CZ 3.42Å; I307-F365 HydrophobicContact CG2-CE2 3.59Å; I307-F365 HydrophobicContact CG2-CZ 3.7Å
308E89.1Confident88.4Confident123 Ų12343.5 Ų43.558%0.57523%0.232SC*.Hα-helixtrans-55.4-43.1-177-64.1170.6-152.400113.2S305 L311 K312S305-E308 WeakPolarHBondContact CB-OE1 3.24Å; S305-E308 PolarHBondContact OG-OE1 3.37Å; E308-L311 PolarHBondContact O-N 3.34Å; E308-K312 PolarHBondContact O-N 3.49Å; E308-K312 VanDerWaalsContact O-N 3.14Å
309P89.4Confident88.2Confident47 Ų4743.7 Ų43.731%0.30523%0.23SC..Hα-helixtrans-65-38.5174.9-22.136.3000112.6L278 S305 G306 L311 K312 D313L278-P309 HydrophobicContact CD1-CB 3.93Å; L278-P309 HydrophobicContact CD1-CG 3.8Å; L278-P309 HydrophobicContact CD2-CB 4.2Å; S305-P309 WeakPolarHBondContact O-CD 3.36Å; G306-P309 WeakPolarHBondContact O-CD 3.24Å; P309-L311 VanDerWaalsContact C-N 3.32Å; P309-L311 PolarHBondContact O-N 3.06Å; P309-K312 WeakPolarHBondContact O-CB 3.45Å; P309-K312 PolarHBondContact O-N 3.31Å; P309-K312 VanDerWaalsContact O-N 3.16Å; P309-D313 VanDerWaalsContact O-CG 3.3Å; P309-D313 PolarHBondContact O-N 2.89Å
310M90.8Very high88.1Confident0 Ų048.5 Ų48.50%026%0.255CS..Hα-helixtrans-63.7-38177.3-62.9-178.85600112.1L278 M296 F297 M300 I307 K312 L314 F359 F365L278-M310 HydrophobicContact CD2-CG 3.58Å; L278-M310 HydrophobicContact CD2-SD 4.38Å; M296-M310 HydrophobicContact CE-CE 3.39Å; M296-M310 HydrophobicContact CE-CG 4.21Å; M296-M310 HydrophobicContact CE-SD 3.96Å; M296-M310 HydrophobicContact CG-CE 4.3Å; M296-M310 HydrophobicContact CG-SD 4.2Å; F297-M310 HydrophobicContact CB-CE 4.09Å; M300-M310 HydrophobicContact CB-SD 3.75Å; M300-M310 HydrophobicContact CG-SD 3.71Å; I307-M310 WeakPolarHBondContact O-CB 3.21Å; I307-M310 PolarHBondContact O-N 2.94Å; M310-K312 VanDerWaalsContact C-N 3.35Å; M310-L314 WeakPolarHBondContact O-CB 3.33Å; M310-L314 PolarHBondContact O-N 2.55Å; M310-F359 HydrophobicContact CE-CD1 4.48Å; M310-F359 HydrophobicContact CE-CE1 3.59Å; M310-F359 HydrophobicContact CE-CZ 4.32Å; M310-F365 HydrophobicContact CB-CE1 4.18Å; M310-F365 HydrophobicContact CB-CZ 4.04Å; M310-F365 HydrophobicContact CE-CZ 4.15Å
311L90.4Very high87.8Confident28 Ų2849.3 Ų49.315%0.14726%0.262CS..Hα-helixtrans-62.5-45.2174-65.7169.8000110.5I307 E308 P309 L314 E315 R364 F365 A368I307-L311 HydrophobicContact CG2-CD1 4.13Å; I307-L311 HydrophobicContact CG2-CD2 4.43Å; I307-L311 HydrophobicContact CG2-CG 3.95Å; I307-L311 WeakPolarHBondContact O-CG 3.31Å; I307-L311 PolarHBondContact O-N 2.85Å; E308-L311 PolarHBondContact O-N 3.34Å; P309-L311 VanDerWaalsContact C-N 3.32Å; P309-L311 PolarHBondContact O-N 3.06Å; L311-L314 PolarHBondContact O-N 3.04Å; L311-E315 WeakPolarHBondContact O-CB 3.28Å; L311-E315 WeakPolarHBondContact O-CG 3.36Å; L311-E315 PolarHBondContact O-N 2.78Å; L311-R364 HydrophobicContact CD1-CB 4.15Å; L311-R364 HydrophobicContact CD2-CB 4.07Å; L311-F365 HydrophobicContact CD2-CB 4.3Å; L311-F365 HydrophobicContact CD2-CD1 3.6Å; L311-F365 HydrophobicContact CD2-CD2 3.88Å; L311-F365 HydrophobicContact CD2-CE1 3.79Å; L311-F365 HydrophobicContact CD2-CE2 4.06Å; L311-F365 HydrophobicContact CD2-CG 3.67Å; L311-F365 HydrophobicContact CD2-CZ 4.02Å; L311-F365 HydrophobicContact CG-CE1 4.44Å; L311-F365 HydrophobicContact CG-CZ 4.5Å; L311-A368 HydrophobicContact CB-CB 4.38Å; L311-A368 HydrophobicContact CD2-CB 3.9Å
312K90Very high87.4Confident118 Ų11845.5 Ų45.551%0.51324%0.242SC..Hα-helixtrans-63.3-43.9178.4-171.6-178.9171.4-170.70112.1E308 P309 M310 L314 E315 E316E308-K312 PolarHBondContact O-N 3.49Å; E308-K312 VanDerWaalsContact O-N 3.14Å; P309-K312 WeakPolarHBondContact O-CB 3.45Å; P309-K312 PolarHBondContact O-N 3.31Å; P309-K312 VanDerWaalsContact O-N 3.16Å; M310-K312 VanDerWaalsContact C-N 3.35Å; K312-L314 VanDerWaalsContact C-N 3.34Å; K312-L314 PolarHBondContact O-N 3.47Å; K312-E315 WeakPolarHBondContact O-CB 3.35Å; K312-E315 PolarHBondContact O-N 2.82Å; K312-E316 WeakPolarHBondContact CE-OE1 3Å; K312-E316 IonicContact NZ-OE1 2.89Å; K312-E316 WeakPolarHBondContact O-CG 3.32Å; K312-E316 PolarHBondContact O-N 3.27Å
313D89.4Confident87.1Confident32 Ų3242.7 Ų42.717%0.17123%0.231CC..Hα-helixtrans-63.3-40.5178-69.1-22.9000112C281 P282 I285 P309 H317C281-D313 PolarHBondContact SG-OD2 3.05Å; P282-D313 HydrophobicContact CG-CB 4.27Å; I285-D313 HydrophobicContact CD1-CB 4.07Å; P309-D313 VanDerWaalsContact O-CG 3.3Å; P309-D313 PolarHBondContact O-N 2.89Å; D313-H317 VanDerWaalsContact O-CB 3.26Å; D313-H317 WeakPolarHBondContact O-CB 3.23Å; D313-H317 PolarHBondContact O-N 3.43Å
314L89.6Confident86.8Confident0 Ų044.9 Ų44.90%025%0.25CS..Hα-helixtrans-65-44.9174-178.468.2000111.1I285 M310 L311 K312 H317 I318 L354 V355 F359 F365I285-L314 HydrophobicContact CD1-CB 4.19Å; I285-L314 HydrophobicContact CD1-CD1 4.48Å; I285-L314 HydrophobicContact CG2-CD1 4.17Å; M310-L314 WeakPolarHBondContact O-CB 3.33Å; M310-L314 PolarHBondContact O-N 2.55Å; L311-L314 PolarHBondContact O-N 3.04Å; K312-L314 VanDerWaalsContact C-N 3.34Å; K312-L314 PolarHBondContact O-N 3.47Å; L314-H317 PolarHBondContact O-N 3.12Å; L314-I318 HydrophobicContact CD1-CD1 3.92Å; L314-I318 HydrophobicContact CD1-CG1 4.16Å; L314-I318 HydrophobicContact CD2-CD1 4.3Å; L314-I318 HydrophobicContact CG-CD1 3.73Å; L314-I318 HydrophobicContact CG-CG1 4.35Å; L314-I318 WeakPolarHBondContact O-CB 3.36Å; L314-I318 VanDerWaalsContact O-CG1 3.22Å; L314-I318 WeakPolarHBondContact O-CG1 3.38Å; L314-I318 PolarHBondContact O-N 2.85Å; L314-L354 HydrophobicContact CD1-CD2 3.93Å; L314-V355 HydrophobicContact CD2-CG2 3.94Å; L314-F359 HydrophobicContact CD2-CE2 4.13Å; L314-F365 HydrophobicContact CD2-CD1 3.72Å
315E90.2Very high86.6Confident25 Ų2542.4 Ų42.412%0.11723%0.231CC..Hα-helixtrans-56.2-52.3176.8-74165.2-159.100111L311 K312 H317 I318 I319 A368 K372L311-E315 WeakPolarHBondContact O-CB 3.28Å; L311-E315 WeakPolarHBondContact O-CG 3.36Å; L311-E315 PolarHBondContact O-N 2.78Å; K312-E315 WeakPolarHBondContact O-CB 3.35Å; K312-E315 PolarHBondContact O-N 2.82Å; E315-H317 PolarHBondContact O-N 3.14Å; E315-I318 PolarHBondContact O-N 3.36Å; E315-I319 WeakPolarHBondContact O-CD1 3.45Å; E315-I319 VanDerWaalsContact O-CG1 3.23Å; E315-I319 WeakPolarHBondContact O-CG1 3.19Å; E315-I319 PolarHBondContact O-N 2.89Å; E315-A368 HydrophobicContact CG-CB 3.82Å; E315-A368 WeakPolarHBondContact OE1-CB 3.15Å; E315-K372 VanDerWaalsContact CD-NZ 3.33Å; E315-K372 HydrophobicContact CG-CB 4.25Å; E315-K372 HydrophobicContact CG-CD 4.28Å; E315-K372 WeakPolarHBondContact OE1-CD 3.17Å; E315-K372 IonicContact OE1-NZ 2.79Å; E315-K372 PolarHBondContact OE1-NZ 2.89Å; E315-K372 WeakPolarHBondContact OE2-CD 3.14Å; E315-K372 IonicContact OE2-NZ 2.7Å; E315-K372 PolarHBondContact OE2-NZ 3.4Å
316E89.4Confident86.2Confident89 Ų8939 Ų3942%0.41621%0.207SC..Hα-helixtrans-63.6-40.3179.5-73-177.3-172.300112K312 I319 N320K312-E316 WeakPolarHBondContact CE-OE1 3Å; K312-E316 IonicContact NZ-OE1 2.89Å; K312-E316 WeakPolarHBondContact O-CG 3.32Å; K312-E316 PolarHBondContact O-N 3.27Å; E316-I319 PolarHBondContact O-N 3.1Å; E316-N320 VanDerWaalsContact O-CB 3.26Å; E316-N320 WeakPolarHBondContact O-CB 3.26Å; E316-N320 PolarHBondContact O-N 3.43Å; E316-N320 PolarHBondContact O-ND2 2.87Å
317H89.3Confident85.7Confident29 Ų2943.1 Ų43.113%0.13423%0.231CC..Hα-helixtrans-64.3-45.7177.8179.164.3000112.2I285 K286 D313 L314 E315 I319 N320 A321 F351I285-H317 HydrophobicContact CG2-CB 3.86Å; I285-H317 WeakPolarHBondContact CG2-CD2 3.14Å; K286-H317 VanDerWaalsContact CG-CE1 3.47Å; K286-H317 WeakPolarHBondContact CG-CE1 3.26Å; K286-H317 WeakPolarHBondContact CG-ND1 3.24Å; D313-H317 VanDerWaalsContact O-CB 3.26Å; D313-H317 WeakPolarHBondContact O-CB 3.23Å; D313-H317 PolarHBondContact O-N 3.43Å; L314-H317 PolarHBondContact O-N 3.12Å; E315-H317 PolarHBondContact O-N 3.14Å; H317-I319 VanDerWaalsContact C-N 3.34Å; H317-I319 PolarHBondContact O-N 3.16Å; H317-N320 PolarHBondContact O-N 3.32Å; H317-A321 WeakPolarHBondContact O-CB 3.48Å; H317-A321 PolarHBondContact O-N 3.4Å; H317-F351 AromaticContact CD2-CE1 3.45Å; H317-F351 VanDerWaalsContact CD2-CE1 3.45Å; H317-F351 WeakPolarHBondContact CD2-CE1 3.09Å; H317-F351 AromaticContact CD2-CZ 3.74Å; H317-F351 AromaticContact NE2-CE1 3.57Å; H317-F351 AromaticContact NE2-CZ 3.73Å
318I87.6Confident84.9Confident1 Ų146.9 Ų46.91%0.00526%0.264CS..Hα-helixtrans-62-44.2178.5-67.1168.4000110.4L314 E315 G322 F351 R369 A373L314-I318 HydrophobicContact CD1-CD1 3.92Å; L314-I318 HydrophobicContact CD1-CG1 4.16Å; L314-I318 HydrophobicContact CD2-CD1 4.3Å; L314-I318 HydrophobicContact CG-CD1 3.73Å; L314-I318 HydrophobicContact CG-CG1 4.35Å; L314-I318 WeakPolarHBondContact O-CB 3.36Å; L314-I318 VanDerWaalsContact O-CG1 3.22Å; L314-I318 WeakPolarHBondContact O-CG1 3.38Å; L314-I318 PolarHBondContact O-N 2.85Å; E315-I318 PolarHBondContact O-N 3.36Å; I318-G322 PolarHBondContact O-N 3.33Å; I318-F351 HydrophobicContact CB-CD2 4.23Å; I318-F351 HydrophobicContact CB-CE2 4.08Å; I318-F351 HydrophobicContact CB-CZ 4.4Å; I318-F351 HydrophobicContact CD1-CB 4.25Å; I318-F351 HydrophobicContact CD1-CD1 4.44Å; I318-F351 HydrophobicContact CD1-CG 4.2Å; I318-F351 HydrophobicContact CG1-CB 4.28Å; I318-F351 HydrophobicContact CG1-CD1 3.75Å; I318-F351 HydrophobicContact CG1-CD2 3.77Å; I318-F351 HydrophobicContact CG1-CE1 3.94Å; I318-F351 HydrophobicContact CG1-CE2 3.89Å; I318-F351 HydrophobicContact CG1-CG 3.68Å; I318-F351 HydrophobicContact CG1-CZ 4Å; I318-F351 HydrophobicContact CG2-CD2 3.87Å; I318-F351 HydrophobicContact CG2-CE2 3.97Å; I318-R369 HydrophobicContact CD1-CB 4.15Å; I318-R369 HydrophobicContact CD1-CG 3.98Å; I318-A373 HydrophobicContact CB-CB 3.69Å; I318-A373 HydrophobicContact CD1-CB 4.1Å; I318-A373 HydrophobicContact CG2-CB 3.57Å
319I86.5Confident83.8Confident44 Ų4442 Ų4223%0.22625%0.245CC..Hα-helixtrans-62.6-52178.5-66.9166.4000110.3E315 E316 H317 A321 G322 L323 A373 A376 V377E315-I319 WeakPolarHBondContact O-CD1 3.45Å; E315-I319 VanDerWaalsContact O-CG1 3.23Å; E315-I319 WeakPolarHBondContact O-CG1 3.19Å; E315-I319 PolarHBondContact O-N 2.89Å; E316-I319 PolarHBondContact O-N 3.1Å; H317-I319 VanDerWaalsContact C-N 3.34Å; H317-I319 PolarHBondContact O-N 3.16Å; I319-A321 PolarHBondContact O-N 2.95Å; I319-G322 PolarHBondContact O-N 3.32Å; I319-L323 HydrophobicContact CG2-CD1 3.79Å; I319-L323 HydrophobicContact CG2-CG 4.33Å; I319-L323 WeakPolarHBondContact O-CB 3.22Å; I319-L323 VanDerWaalsContact O-CG 3.27Å; I319-L323 WeakPolarHBondContact O-CG 3.4Å; I319-L323 PolarHBondContact O-N 2.9Å; I319-A373 HydrophobicContact CG1-CB 4.07Å; I319-A376 HydrophobicContact CD1-CB 3.91Å; I319-A376 HydrophobicContact CG1-CB 4.06Å; I319-V377 HydrophobicContact CB-CG2 4.49Å; I319-V377 HydrophobicContact CG1-CG2 4.39Å
320N87.4Confident82.5Confident101 Ų10141 Ų4154%0.5424%0.24SC..Hα-helixtrans-63.7-42.5-177.6-71.9-35.1000112.2E316 H317 A324E316-N320 VanDerWaalsContact O-CB 3.26Å; E316-N320 WeakPolarHBondContact O-CB 3.26Å; E316-N320 PolarHBondContact O-N 3.43Å; E316-N320 PolarHBondContact O-ND2 2.87Å; H317-N320 PolarHBondContact O-N 3.32Å; N320-A324 VanDerWaalsContact O-CB 3.24Å; N320-A324 WeakPolarHBondContact O-CB 3.3Å; N320-A324 PolarHBondContact O-N 3.03Å
321A85.5Confident81Confident16 Ų1649.5 Ų49.513%0.13228%0.28CS..Hα-helixtrans-66.8-43.517700000111.4H317 I319 A324 D325 F351H317-A321 WeakPolarHBondContact O-CB 3.48Å; H317-A321 PolarHBondContact O-N 3.4Å; I319-A321 PolarHBondContact O-N 2.95Å; A321-A324 PolarHBondContact O-N 2.78Å; A321-D325 WeakPolarHBondContact O-CB 3.49Å; A321-D325 PolarHBondContact O-N 3.3Å; A321-F351 HydrophobicContact CB-CE2 4.28Å; A321-F351 HydrophobicContact CB-CZ 3.86Å
322G81.6Confident79.7Confident0 Ų051.2 Ų51.20%029%0.291CS..Hα-helixtrans-61.5-46.9177.300000112.6I318 I319 D325 M326 L347I318-G322 PolarHBondContact O-N 3.33Å; I319-G322 PolarHBondContact O-N 3.32Å; G322-D325 PolarHBondContact O-N 2.82Å; G322-M326 WeakPolarHBondContact O-CB 3.27Å; G322-M326 WeakPolarHBondContact O-CG 3.45Å; G322-M326 PolarHBondContact O-N 3.21Å; G322-L347 VanDerWaalsContact CA-CD2 3.46Å
323L80.1Confident78.1Confident35 Ų3545.6 Ų45.618%0.18327%0.267CS..Hα-helixtrans-64.7-41.7176.7-66.6176.4000111.7I319 M326 V327 D380 I383I319-L323 HydrophobicContact CG2-CD1 3.79Å; I319-L323 HydrophobicContact CG2-CG 4.33Å; I319-L323 WeakPolarHBondContact O-CB 3.22Å; I319-L323 VanDerWaalsContact O-CG 3.27Å; I319-L323 WeakPolarHBondContact O-CG 3.4Å; I319-L323 PolarHBondContact O-N 2.9Å; L323-M326 PolarHBondContact O-N 2.8Å; L323-V327 WeakPolarHBondContact O-CB 3.22Å; L323-V327 VanDerWaalsContact O-CG2 3.3Å; L323-V327 WeakPolarHBondContact O-CG2 3.45Å; L323-V327 PolarHBondContact O-N 3.42Å; L323-D380 HydrophobicContact CD2-CB 3.76Å; L323-I383 HydrophobicContact CB-CD1 4.21Å; L323-I383 HydrophobicContact CD2-CD1 3.71Å; L323-I383 WeakPolarHBondContact O-CD1 3.42Å
324A81.6Confident76.5Confident55 Ų5548.5 Ų48.546%0.45529%0.286SS..Hα-helixtrans-62.6-45.7176.500000112.2N320 A321 M326 V327 A328N320-A324 VanDerWaalsContact O-CB 3.24Å; N320-A324 WeakPolarHBondContact O-CB 3.3Å; N320-A324 PolarHBondContact O-N 3.03Å; A321-A324 PolarHBondContact O-N 2.78Å; A324-M326 VanDerWaalsContact C-N 3.29Å; A324-M326 PolarHBondContact O-N 3.06Å; A324-V327 PolarHBondContact O-N 3.25Å; A324-A328 WeakPolarHBondContact O-CB 3.43Å; A324-A328 PolarHBondContact O-N 3.19Å
325D77.6Confident75Confident55 Ų5554.5 Ų54.529%0.29432%0.323SS..Hα-helixtrans-61.1-40.2177.2-70.3-20.2000110.4A321 G322 A329 R350A321-D325 WeakPolarHBondContact O-CB 3.49Å; A321-D325 PolarHBondContact O-N 3.3Å; G322-D325 PolarHBondContact O-N 2.82Å; D325-A329 PolarHBondContact O-N 3.22Å; D325-R350 IonicContact OD2-CZ 3.61Å; D325-R350 IonicContact OD2-NH1 3.91Å; D325-R350 PolarHBondContact OD2-NH1 3.22Å; D325-R350 IonicContact OD2-NH2 2.83Å; D325-R350 PolarHBondContact OD2-NH2 2.93Å
326M71.9Confident74Confident7 Ų755.1 Ų55.13%0.03433%0.327CS..Hα-helixtrans-70.2-39.2176.8-71.617184.200113.6G322 L323 A324 A330 Y340 L344 V377 I383 F384G322-M326 WeakPolarHBondContact O-CB 3.27Å; G322-M326 WeakPolarHBondContact O-CG 3.45Å; G322-M326 PolarHBondContact O-N 3.21Å; L323-M326 PolarHBondContact O-N 2.8Å; A324-M326 VanDerWaalsContact C-N 3.29Å; A324-M326 PolarHBondContact O-N 3.06Å; M326-A330 PolarHBondContact O-N 3.29Å; M326-Y340 HydrophobicContact CE-CE2 3.47Å; M326-Y340 VanDerWaalsContact CE-CE2 3.47Å; M326-Y340 WeakPolarHBondContact CE-OH 3.5Å; M326-L344 HydrophobicContact CE-CD2 4.36Å; M326-L344 HydrophobicContact SD-CD2 4.12Å; M326-V377 HydrophobicContact SD-CG1 3.49Å; M326-V377 WeakPolarHBondContact SD-CG1 3.44Å; M326-I383 HydrophobicContact CB-CD1 3.55Å; M326-F384 HydrophobicContact CB-CE2 4.28Å; M326-F384 HydrophobicContact CE-CD2 3.94Å; M326-F384 HydrophobicContact CE-CE2 4.05Å
327V73.3Confident73Confident89 Ų8951.7 Ų51.754%0.53931%0.313SS..Hα-helixtrans-66-46175.4169.20000110.4L323 A324 A329 A330 I383L323-V327 WeakPolarHBondContact O-CB 3.22Å; L323-V327 VanDerWaalsContact O-CG2 3.3Å; L323-V327 WeakPolarHBondContact O-CG2 3.45Å; L323-V327 PolarHBondContact O-N 3.42Å; A324-V327 PolarHBondContact O-N 3.25Å; V327-A329 PolarHBondContact O-N 3.08Å; V327-A330 VanDerWaalsContact O-CB 3.22Å; V327-A330 WeakPolarHBondContact O-CB 3.36Å; V327-A330 PolarHBondContact O-N 2.93Å; V327-A330 VanDerWaalsContact O-N 3.08Å; V327-I383 HydrophobicContact CG2-CD1 3.58Å; V327-I383 HydrophobicContact CG2-CG1 3.79Å; V327-I383 HydrophobicContact CG2-CG2 4.45Å
328A72Confident72.4Confident91 Ų9152.4 Ų52.475%0.75232%0.316SS*.Hα-helixtrans-60.5-31.6-17900000112.4A324A324-A328 WeakPolarHBondContact O-CB 3.43Å; A324-A328 PolarHBondContact O-N 3.19Å
329A67.2Low71.9Confident21 Ų2157.1 Ų57.117%0.17434%0.336CS..THydrogen-bonded Turntrans-96.13.3178.900000114D325 V327 E331 T332 I333D325-A329 PolarHBondContact O-N 3.22Å; V327-A329 PolarHBondContact O-N 3.08Å; A329-E331 PolarHBondContact O-N 2.96Å; A329-T332 PolarHBondContact O-N 3.29Å; A329-T332 VanDerWaalsContact O-N 3.08Å; A329-I333 HydrophobicContact CB-CD1 3.29Å; A329-I333 HydrophobicContact CB-CG1 3.94Å; A329-I333 WeakPolarHBondContact O-CB 3.34Å; A329-I333 WeakPolarHBondContact O-CD1 3.43Å; A329-I333 WeakPolarHBondContact O-CG1 3.12Å; A329-I333 PolarHBondContact O-N 3.45Å
330A62Low71.5Confident26 Ų2655.1 Ų55.122%0.21533%0.326CS..Hα-helixtrans-57.9-40.5-169.900000114.7M326 V327 T332 I333 T334 I383 F384M326-A330 PolarHBondContact O-N 3.29Å; V327-A330 VanDerWaalsContact O-CB 3.22Å; V327-A330 WeakPolarHBondContact O-CB 3.36Å; V327-A330 PolarHBondContact O-N 2.93Å; V327-A330 VanDerWaalsContact O-N 3.08Å; A330-T332 VanDerWaalsContact C-N 3.32Å; A330-T332 PolarHBondContact O-N 2.87Å; A330-I333 PolarHBondContact O-N 3.45Å; A330-T334 WeakPolarHBondContact O-CG2 3.15Å; A330-T334 PolarHBondContact O-N 3.42Å; A330-T334 VanDerWaalsContact O-N 3.14Å; A330-T334 PolarHBondContact O-OG1 3.09Å; A330-I383 HydrophobicContact CB-CG2 4.39Å; A330-F384 HydrophobicContact CB-CE1 4.34Å; A330-F384 HydrophobicContact CB-CZ 4.17Å
331E59.3Low71.1Confident178 Ų17850.3 Ų50.383%0.83230%0.3SS*.Hα-helixtrans-65.5-34.5178.6-67.5-17116700112.6A329 T334A329-E331 PolarHBondContact O-N 2.96Å; E331-T334 PolarHBondContact O-OG1 3.46Å
332T61.5Low71Confident63 Ų6352.6 Ų52.639%0.38731%0.309SS..Hα-helixtrans-83.1-37.3178.9-53.70000111.2A329 A330 T335 D336 K339A329-T332 PolarHBondContact O-N 3.29Å; A329-T332 VanDerWaalsContact O-N 3.08Å; A330-T332 VanDerWaalsContact C-N 3.32Å; A330-T332 PolarHBondContact O-N 2.87Å; T332-T335 PolarHBondContact O-N 3.46Å; T332-T335 PolarHBondContact O-OG1 3.44Å; T332-D336 WeakPolarHBondContact O-CB 3.32Å; T332-D336 PolarHBondContact O-N 2.89Å; T332-K339 HydrophobicContact CG2-CD 3.45Å; T332-K339 VanDerWaalsContact CG2-CD 3.45Å; T332-K339 VanDerWaalsContact CG2-NZ 3.33Å
333I57.5Low71Confident1 Ų156.6 Ų56.61%0.00533%0.327CS..Hα-helixtrans-66.6-36.9-177.7-76.1163.6000112.8A329 A330 T335 D336 Y340 F384A329-I333 HydrophobicContact CB-CD1 3.29Å; A329-I333 HydrophobicContact CB-CG1 3.94Å; A329-I333 WeakPolarHBondContact O-CB 3.34Å; A329-I333 WeakPolarHBondContact O-CD1 3.43Å; A329-I333 WeakPolarHBondContact O-CG1 3.12Å; A329-I333 PolarHBondContact O-N 3.45Å; A330-I333 PolarHBondContact O-N 3.45Å; I333-T335 PolarHBondContact O-N 2.96Å; I333-D336 CarbonylContact O-C 3.47Å; I333-D336 PolarHBondContact O-N 3.11Å; I333-D336 VanDerWaalsContact O-N 3.1Å; I333-Y340 HydrophobicContact CB-CD2 4.48Å; I333-Y340 HydrophobicContact CD1-CD2 3.96Å; I333-Y340 HydrophobicContact CG1-CD2 4.24Å; I333-Y340 HydrophobicContact CG2-CD2 3.47Å; I333-Y340 VanDerWaalsContact CG2-CD2 3.47Å; I333-Y340 HydrophobicContact CG2-CE2 4.35Å; I333-Y340 HydrophobicContact CG2-CG 3.88Å; I333-F384 HydrophobicContact CB-CE1 3.95Å; I333-F384 HydrophobicContact CB-CZ 3.69Å; I333-F384 HydrophobicContact CD1-CE2 4.24Å; I333-F384 HydrophobicContact CD1-CZ 3.82Å; I333-F384 HydrophobicContact CG1-CZ 4.36Å; I333-F384 HydrophobicContact CG2-CD1 4.08Å; I333-F384 HydrophobicContact CG2-CE1 3.3Å; I333-F384 HydrophobicContact CG2-CE2 3.89Å; I333-F384 HydrophobicContact CG2-CZ 3.19Å
334T55.5Low71.1Confident93 Ų9355 Ų5557%0.57132%0.319SS*.THydrogen-bonded Turntrans-59.7-24.1-17944.80000112.9A330 E331 F384A330-T334 WeakPolarHBondContact O-CG2 3.15Å; A330-T334 PolarHBondContact O-N 3.42Å; A330-T334 VanDerWaalsContact O-N 3.14Å; A330-T334 PolarHBondContact O-OG1 3.09Å; E331-T334 PolarHBondContact O-OG1 3.46Å; T334-F384 HydrophobicContact CG2-CD1 4.44Å; T334-F384 HydrophobicContact CG2-CE1 4.16Å
335T57.7Low71.2Confident125 Ų12553 Ų5377%0.76730%0.3SS*.THydrogen-bonded Turntrans-101.8-17.8176.152.50000114.8T332 I333T332-T335 PolarHBondContact O-N 3.46Å; T332-T335 PolarHBondContact O-OG1 3.44Å; I333-T335 PolarHBondContact O-N 2.96Å
336D69.6Low71.6Confident39 Ų3954.2 Ų54.221%0.20931%0.31CS..  trans-134.896.1-167.8-166.7-7.5000112T332 I333 E338 K339T332-D336 WeakPolarHBondContact O-CB 3.32Å; T332-D336 PolarHBondContact O-N 2.89Å; I333-D336 CarbonylContact O-C 3.47Å; I333-D336 PolarHBondContact O-N 3.11Å; I333-D336 VanDerWaalsContact O-N 3.1Å; D336-E338 PolarHBondContact O-N 3.42Å; D336-E338 WeakPolarHBondContact OD1-CB 3.26Å; D336-E338 PolarHBondContact OD1-N 3.43Å; D336-K339 HydrophobicContact CB-CD 4.37Å; D336-K339 VanDerWaalsContact OD2-CD 3.31Å; D336-K339 WeakPolarHBondContact OD2-CD 3.35Å; D336-K339 VanDerWaalsContact OD2-CE 3.29Å; D336-K339 WeakPolarHBondContact OD2-CE 3.37Å; D336-K339 WeakPolarHBondContact OD2-CG 3.49Å; D336-K339 IonicContact OD2-NZ 3.21Å
337S69.3Low72.3Confident16 Ų1654.1 Ų54.111%0.11231%0.31CS..Hα-helixtrans-66.1-22.7178.948.40000113.6V341 M415S337-V341 WeakPolarHBondContact O-CG2 3.34Å; S337-V341 PolarHBondContact O-N 3.48Å; S337-M415 PolarHBondContact OG-SD 3.14Å; S337-M415 VanDerWaalsContact OG-SD 3.34Å
338E75.9Confident72.9Confident45 Ų4550.9 Ų50.921%0.2129%0.288CS..Hα-helixtrans-66-54.2177.6169.5179.817700110.5D336 Y340 V341 E342 Y412 M415 L422D336-E338 PolarHBondContact O-N 3.42Å; D336-E338 WeakPolarHBondContact OD1-CB 3.26Å; D336-E338 PolarHBondContact OD1-N 3.43Å; E338-Y340 PolarHBondContact O-N 2.96Å; E338-V341 PolarHBondContact O-N 3.41Å; E338-V341 VanDerWaalsContact O-N 3.16Å; E338-E342 WeakPolarHBondContact O-CG 3.43Å; E338-E342 PolarHBondContact O-N 2.95Å; E338-Y412 HydrophobicContact CB-CD2 4.04Å; E338-Y412 HydrophobicContact CB-CE2 3.85Å; E338-Y412 HydrophobicContact CG-CE2 3.91Å; E338-M415 HydrophobicContact CB-CE 4.33Å; E338-L422 HydrophobicContact CG-CD2 4.26Å; E338-L422 WeakPolarHBondContact OE1-CD1 3.32Å; E338-L422 WeakPolarHBondContact OE2-CD2 3.39Å
339K77.4Confident73.6Confident99 Ų9950.3 Ų50.343%0.4327%0.272SS..Hα-helixtrans-59.4-35.3179.8-71.6178.3-177.2179.40112.8T332 D336 Q343T332-K339 HydrophobicContact CG2-CD 3.45Å; T332-K339 VanDerWaalsContact CG2-CD 3.45Å; T332-K339 VanDerWaalsContact CG2-NZ 3.33Å; D336-K339 HydrophobicContact CB-CD 4.37Å; D336-K339 VanDerWaalsContact OD2-CD 3.31Å; D336-K339 WeakPolarHBondContact OD2-CD 3.35Å; D336-K339 VanDerWaalsContact OD2-CE 3.29Å; D336-K339 WeakPolarHBondContact OD2-CE 3.37Å; D336-K339 WeakPolarHBondContact OD2-CG 3.49Å; D336-K339 IonicContact OD2-NZ 3.21Å; K339-Q343 WeakPolarHBondContact O-CB 3.26Å; K339-Q343 WeakPolarHBondContact O-CG 3.48Å; K339-Q343 PolarHBondContact O-N 3.32Å
340Y77.8Confident74.6Confident2 Ų253.9 Ų53.91%0.00828%0.281CS..Hα-helixtrans-59.4-52.9176-178.4-111.8000112.6M326 I333 E338 Q343 L344 F384 C405 L408M326-Y340 HydrophobicContact CE-CE2 3.47Å; M326-Y340 VanDerWaalsContact CE-CE2 3.47Å; M326-Y340 WeakPolarHBondContact CE-OH 3.5Å; I333-Y340 HydrophobicContact CB-CD2 4.48Å; I333-Y340 HydrophobicContact CD1-CD2 3.96Å; I333-Y340 HydrophobicContact CG1-CD2 4.24Å; I333-Y340 HydrophobicContact CG2-CD2 3.47Å; I333-Y340 VanDerWaalsContact CG2-CD2 3.47Å; I333-Y340 HydrophobicContact CG2-CE2 4.35Å; I333-Y340 HydrophobicContact CG2-CG 3.88Å; E338-Y340 PolarHBondContact O-N 2.96Å; Y340-Q343 PolarHBondContact O-N 3.32Å; Y340-L344 HydrophobicContact CD1-CD1 4.07Å; Y340-L344 HydrophobicContact CE1-CD1 3.48Å; Y340-L344 VanDerWaalsContact CE1-CD1 3.48Å; Y340-L344 HydrophobicContact CE1-CG 4.46Å; Y340-L344 HydrophobicContact CE2-CD1 4.38Å; Y340-L344 PolarHBondContact O-N 3.49Å; Y340-L344 VanDerWaalsContact O-N 3.15Å; Y340-F384 HydrophobicContact CD2-CD2 4.24Å; Y340-F384 AromaticContact CD2-CE2 3.88Å; Y340-F384 HydrophobicContact CD2-CE2 3.88Å; Y340-F384 HydrophobicContact CD2-CZ 4.41Å; Y340-F384 AromaticContact CE2-CD2 3.48Å; Y340-F384 HydrophobicContact CE2-CD2 3.48Å; Y340-F384 VanDerWaalsContact CE2-CD2 3.48Å; Y340-F384 AromaticContact CE2-CE2 3.44Å; Y340-F384 HydrophobicContact CE2-CE2 3.44Å; Y340-F384 VanDerWaalsContact CE2-CE2 3.44Å; Y340-F384 HydrophobicContact CE2-CG 4.42Å; Y340-F384 HydrophobicContact CE2-CZ 4.36Å; Y340-C405 HydrophobicContact CE1-CB 4.21Å; Y340-C405 WeakPolarHBondContact OH-CB 3.46Å; Y340-L408 HydrophobicContact CD1-CB 3.81Å; Y340-L408 HydrophobicContact CD1-CD1 3.62Å; Y340-L408 HydrophobicContact CD1-CG 4.36Å; Y340-L408 HydrophobicContact CD2-CD1 4.28Å; Y340-L408 HydrophobicContact CE1-CB 4.11Å; Y340-L408 HydrophobicContact CE1-CD1 3.74Å; Y340-L408 HydrophobicContact CE2-CD1 4.36Å; Y340-L408 HydrophobicContact CG-CD1 3.88Å
341V79.4Confident75.9Confident0 Ų052.7 Ų52.70%027%0.272CS..Hα-helixtrans-69-39.8-176.4177.60000110.2S337 E338 Q343 L344 L345 L409 Y412 V438S337-V341 WeakPolarHBondContact O-CG2 3.34Å; S337-V341 PolarHBondContact O-N 3.48Å; E338-V341 PolarHBondContact O-N 3.41Å; E338-V341 VanDerWaalsContact O-N 3.16Å; V341-Q343 VanDerWaalsContact C-N 3.32Å; V341-Q343 PolarHBondContact O-N 2.82Å; V341-L344 PolarHBondContact O-N 2.96Å; V341-L345 HydrophobicContact CG1-CD1 3.95Å; V341-L345 HydrophobicContact CG1-CG 4.26Å; V341-L345 VanDerWaalsContact O-CG 3.3Å; V341-L345 WeakPolarHBondContact O-CG 3.32Å; V341-L345 PolarHBondContact O-N 3.17Å; V341-L409 HydrophobicContact CG1-CD2 4.12Å; V341-L409 HydrophobicContact CG2-CD2 3.7Å; V341-Y412 HydrophobicContact CB-CD1 3.8Å; V341-Y412 HydrophobicContact CB-CE1 4.04Å; V341-Y412 HydrophobicContact CB-CG 4.07Å; V341-Y412 HydrophobicContact CG1-CD1 3.59Å; V341-Y412 HydrophobicContact CG1-CE1 3.64Å; V341-Y412 HydrophobicContact CG1-CG 4.36Å; V341-Y412 HydrophobicContact CG2-CD1 3.93Å; V341-Y412 HydrophobicContact CG2-CG 3.93Å; V341-V438 HydrophobicContact CG1-CG2 3.85Å
342E82.1Confident77.3Confident65 Ų6545.3 Ų45.330%0.30424%0.24SC..Hα-helixtrans-62.3-37.1176.2-70.4-169.6157.600112.9E338 L345 T346 K434E338-E342 WeakPolarHBondContact O-CG 3.43Å; E338-E342 PolarHBondContact O-N 2.95Å; E342-L345 PolarHBondContact O-N 2.93Å; E342-T346 VanDerWaalsContact O-CB 3.31Å; E342-T346 WeakPolarHBondContact O-CB 2.8Å; E342-T346 PolarHBondContact O-N 3.26Å; E342-T346 PolarHBondContact O-OG1 3.03Å; E342-K434 IonicContact OE1-NZ 2.74Å; E342-K434 PolarHBondContact OE1-NZ 2.9Å
343Q83.1Confident78.7Confident84 Ų8448.4 Ų48.439%0.39325%0.248SC..Hα-helixtrans-65.8-42.6174.4-73-63.8-20.600112.1K339 Y340 V341 L345 T346 L347K339-Q343 WeakPolarHBondContact O-CB 3.26Å; K339-Q343 WeakPolarHBondContact O-CG 3.48Å; K339-Q343 PolarHBondContact O-N 3.32Å; Y340-Q343 PolarHBondContact O-N 3.32Å; V341-Q343 VanDerWaalsContact C-N 3.32Å; V341-Q343 PolarHBondContact O-N 2.82Å; Q343-L345 PolarHBondContact O-N 2.8Å; Q343-T346 PolarHBondContact O-N 3.37Å; Q343-L347 WeakPolarHBondContact O-CB 3.43Å; Q343-L347 PolarHBondContact O-N 3.41Å
344L82.4Confident80.2Confident2 Ų248.6 Ų48.61%0.0125%0.249CC..Hα-helixtrans-60.6-45.5174.5-73.9175.9000111.6M326 Y340 V341 L347 F348 Y374 V377M326-L344 HydrophobicContact CE-CD2 4.36Å; M326-L344 HydrophobicContact SD-CD2 4.12Å; Y340-L344 HydrophobicContact CD1-CD1 4.07Å; Y340-L344 HydrophobicContact CE1-CD1 3.48Å; Y340-L344 VanDerWaalsContact CE1-CD1 3.48Å; Y340-L344 HydrophobicContact CE1-CG 4.46Å; Y340-L344 HydrophobicContact CE2-CD1 4.38Å; Y340-L344 PolarHBondContact O-N 3.49Å; Y340-L344 VanDerWaalsContact O-N 3.15Å; V341-L344 PolarHBondContact O-N 2.96Å; L344-L347 WeakPolarHBondContact O-CB 3.03Å; L344-L347 PolarHBondContact O-N 2.8Å; L344-F348 PolarHBondContact O-N 2.98Å; L344-Y374 PolarHBondContact O-OH 3.05Å; L344-V377 HydrophobicContact CD2-CG1 4.19Å
345L83.1Confident81.9Confident11 Ų1144.1 Ų44.16%0.05822%0.221CC..Hα-helixtrans-65.9-39.6178.2-66.3176.3000112.1V341 E342 Q343 L347 F348 N349 E437 V441V341-L345 HydrophobicContact CG1-CD1 3.95Å; V341-L345 HydrophobicContact CG1-CG 4.26Å; V341-L345 VanDerWaalsContact O-CG 3.3Å; V341-L345 WeakPolarHBondContact O-CG 3.32Å; V341-L345 PolarHBondContact O-N 3.17Å; E342-L345 PolarHBondContact O-N 2.93Å; Q343-L345 PolarHBondContact O-N 2.8Å; L345-L347 VanDerWaalsContact C-N 3.34Å; L345-L347 PolarHBondContact O-N 3.32Å; L345-F348 WeakPolarHBondContact O-CB 2.98Å; L345-F348 PolarHBondContact O-N 2.82Å; L345-N349 WeakPolarHBondContact O-CB 3.26Å; L345-N349 PolarHBondContact O-N 3.42Å; L345-N349 PolarHBondContact O-ND2 3.04Å; L345-E437 HydrophobicContact CD1-CB 3.88Å; L345-E437 HydrophobicContact CD2-CB 3.75Å; L345-E437 HydrophobicContact CG-CB 4.44Å; L345-V441 HydrophobicContact CD2-CG2 3.67Å
346T86.6Confident83.5Confident82 Ų8244.5 Ų44.550%0.50321%0.212SC..Hα-helixtrans-61.9-43.1174.4-59.70000111.2E342 Q343 N349 R350E342-T346 VanDerWaalsContact O-CB 3.31Å; E342-T346 WeakPolarHBondContact O-CB 2.8Å; E342-T346 PolarHBondContact O-N 3.26Å; E342-T346 PolarHBondContact O-OG1 3.03Å; Q343-T346 PolarHBondContact O-N 3.37Å; T346-N349 PolarHBondContact O-N 2.96Å; T346-R350 VanDerWaalsContact O-CB 3.26Å; T346-R350 WeakPolarHBondContact O-CB 3.43Å; T346-R350 PolarHBondContact O-N 3.46Å
347L85.5Confident84.5Confident5 Ų547.2 Ų47.23%0.02622%0.224CC..Hα-helixtrans-58.8-47.9174.5-172.574000111.2G322 Q343 L344 L345 R350 F351 Y374 V377G322-L347 VanDerWaalsContact CA-CD2 3.46Å; Q343-L347 WeakPolarHBondContact O-CB 3.43Å; Q343-L347 PolarHBondContact O-N 3.41Å; L344-L347 WeakPolarHBondContact O-CB 3.03Å; L344-L347 PolarHBondContact O-N 2.8Å; L345-L347 VanDerWaalsContact C-N 3.34Å; L345-L347 PolarHBondContact O-N 3.32Å; L347-R350 PolarHBondContact O-N 3.03Å; L347-F351 HydrophobicContact CD1-CD2 3.91Å; L347-F351 HydrophobicContact CD1-CE2 3.39Å; L347-F351 HydrophobicContact CD1-CZ 4.42Å; L347-F351 HydrophobicContact CG-CD2 3.99Å; L347-F351 HydrophobicContact CG-CE2 3.94Å; L347-F351 VanDerWaalsContact O-CD2 3.26Å; L347-F351 WeakPolarHBondContact O-CD2 3.15Å; L347-F351 PolarHBondContact O-N 2.94Å; L347-F351 VanDerWaalsContact O-N 3.11Å; L347-Y374 HydrophobicContact CD2-CE2 4.39Å; L347-V377 HydrophobicContact CD2-CG1 4.11Å
348F85.8Confident85.5Confident20 Ų2046.4 Ų46.49%0.08822%0.218CC..Hα-helixtrans-60.3-47.8178.3-174.4-97.3000111.8L344 L345 F351 S352 Y374 L440L344-F348 PolarHBondContact O-N 2.98Å; L345-F348 WeakPolarHBondContact O-CB 2.98Å; L345-F348 PolarHBondContact O-N 2.82Å; F348-F351 PolarHBondContact O-N 3.36Å; F348-S352 WeakPolarHBondContact CE1-OG 3.17Å; F348-S352 WeakPolarHBondContact O-CB 3.45Å; F348-S352 PolarHBondContact O-N 2.93Å; F348-S352 PolarHBondContact O-OG 3.42Å; F348-Y374 HydrophobicContact CB-CD2 4.44Å; F348-Y374 HydrophobicContact CB-CE2 3.61Å; F348-Y374 HydrophobicContact CD2-CD1 4.13Å; F348-Y374 AromaticContact CD2-CD2 3.94Å; F348-Y374 HydrophobicContact CD2-CD2 3.94Å; F348-Y374 AromaticContact CD2-CE1 3.99Å; F348-Y374 HydrophobicContact CD2-CE1 3.99Å; F348-Y374 AromaticContact CD2-CE2 3.82Å; F348-Y374 HydrophobicContact CD2-CE2 3.82Å; F348-Y374 HydrophobicContact CD2-CG 4.09Å; F348-Y374 AromaticContact CD2-CZ 3.84Å; F348-Y374 HydrophobicContact CG-CE2 4.2Å; F348-L440 HydrophobicContact CD1-CD2 4.09Å; F348-L440 HydrophobicContact CE1-CD2 3.45Å; F348-L440 VanDerWaalsContact CE1-CD2 3.45Å; F348-L440 HydrophobicContact CE2-CD2 4.4Å; F348-L440 HydrophobicContact CZ-CD2 3.64Å; F348-L440 HydrophobicContact CZ-CG 4.44Å
349N87.4Confident86.2Confident79 Ų7944.3 Ų44.342%0.42221%0.209SC..Hα-helixtrans-66.5-40.2-179.2-74.2-24.1000111.7L345 T346 S352 K353L345-N349 WeakPolarHBondContact O-CB 3.26Å; L345-N349 PolarHBondContact O-N 3.42Å; L345-N349 PolarHBondContact O-ND2 3.04Å; T346-N349 PolarHBondContact O-N 2.96Å; N349-S352 PolarHBondContact O-N 2.88Å; N349-K353 WeakPolarHBondContact O-CB 3.43Å; N349-K353 PolarHBondContact O-N 3.49Å
350R88.9Confident86.8Confident96 Ų9645.8 Ų45.836%0.36222%0.217SC..Hα-helixtrans-56.7-52174.9-178.4174.176.1-165.3-1.3111.4D325 T346 L347 K353 L354D325-R350 IonicContact OD2-CZ 3.61Å; D325-R350 IonicContact OD2-NH1 3.91Å; D325-R350 PolarHBondContact OD2-NH1 3.22Å; D325-R350 IonicContact OD2-NH2 2.83Å; D325-R350 PolarHBondContact OD2-NH2 2.93Å; T346-R350 VanDerWaalsContact O-CB 3.26Å; T346-R350 WeakPolarHBondContact O-CB 3.43Å; T346-R350 PolarHBondContact O-N 3.46Å; L347-R350 PolarHBondContact O-N 3.03Å; R350-K353 PolarHBondContact O-N 2.88Å; R350-L354 PolarHBondContact O-N 3.43Å; R350-L354 VanDerWaalsContact O-N 3.09Å
351F88.7Confident87.4Confident2 Ų249 Ų491%0.00923%0.234CC..Hα-helixtrans-78.1-24.8-178.4-69.1-57.7000113.7H317 I318 A321 L347 F348 L354 V355H317-F351 AromaticContact CD2-CE1 3.45Å; H317-F351 VanDerWaalsContact CD2-CE1 3.45Å; H317-F351 WeakPolarHBondContact CD2-CE1 3.09Å; H317-F351 AromaticContact CD2-CZ 3.74Å; H317-F351 AromaticContact NE2-CE1 3.57Å; H317-F351 AromaticContact NE2-CZ 3.73Å; I318-F351 HydrophobicContact CB-CD2 4.23Å; I318-F351 HydrophobicContact CB-CE2 4.08Å; I318-F351 HydrophobicContact CB-CZ 4.4Å; I318-F351 HydrophobicContact CD1-CB 4.25Å; I318-F351 HydrophobicContact CD1-CD1 4.44Å; I318-F351 HydrophobicContact CD1-CG 4.2Å; I318-F351 HydrophobicContact CG1-CB 4.28Å; I318-F351 HydrophobicContact CG1-CD1 3.75Å; I318-F351 HydrophobicContact CG1-CD2 3.77Å; I318-F351 HydrophobicContact CG1-CE1 3.94Å; I318-F351 HydrophobicContact CG1-CE2 3.89Å; I318-F351 HydrophobicContact CG1-CG 3.68Å; I318-F351 HydrophobicContact CG1-CZ 4Å; I318-F351 HydrophobicContact CG2-CD2 3.87Å; I318-F351 HydrophobicContact CG2-CE2 3.97Å; A321-F351 HydrophobicContact CB-CE2 4.28Å; A321-F351 HydrophobicContact CB-CZ 3.86Å; L347-F351 HydrophobicContact CD1-CD2 3.91Å; L347-F351 HydrophobicContact CD1-CE2 3.39Å; L347-F351 HydrophobicContact CD1-CZ 4.42Å; L347-F351 HydrophobicContact CG-CD2 3.99Å; L347-F351 HydrophobicContact CG-CE2 3.94Å; L347-F351 VanDerWaalsContact O-CD2 3.26Å; L347-F351 WeakPolarHBondContact O-CD2 3.15Å; L347-F351 PolarHBondContact O-N 2.94Å; L347-F351 VanDerWaalsContact O-N 3.11Å; F348-F351 PolarHBondContact O-N 3.36Å; F351-L354 HydrophobicContact CD1-CD2 3.89Å; F351-L354 HydrophobicContact CE1-CD2 4.32Å; F351-L354 PolarHBondContact O-N 3.09Å; F351-V355 WeakPolarHBondContact O-CG2 3.44Å; F351-V355 PolarHBondContact O-N 2.97Å
352S88.3Confident87.9Confident23 Ų2350.2 Ų50.216%0.16124%0.241CC..Hα-helixtrans-65.3-42.7170-64.20000111.7F348 N349 V355 K356 R369F348-S352 WeakPolarHBondContact CE1-OG 3.17Å; F348-S352 WeakPolarHBondContact O-CB 3.45Å; F348-S352 PolarHBondContact O-N 2.93Å; F348-S352 PolarHBondContact O-OG 3.42Å; N349-S352 PolarHBondContact O-N 2.88Å; S352-V355 PolarHBondContact O-N 3.24Å; S352-K356 WeakPolarHBondContact O-CB 3.44Å; S352-K356 PolarHBondContact O-N 2.88Å; S352-R369 PolarHBondContact OG-NH1 3.41Å
353K90.3Very high88.3Confident127 Ų12751.4 Ų51.455%0.55225%0.254SS*.Hα-helixtrans-62.3-44.2172.8-173.8178.6177.5-177.60111.7N349 R350 V355 K356 E357N349-K353 WeakPolarHBondContact O-CB 3.43Å; N349-K353 PolarHBondContact O-N 3.49Å; R350-K353 PolarHBondContact O-N 2.88Å; K353-V355 PolarHBondContact O-N 3.27Å; K353-K356 PolarHBondContact O-N 3.31Å; K353-E357 WeakPolarHBondContact CE-OE1 3.41Å; K353-E357 HydrophobicContact CG-CG 4.41Å; K353-E357 IonicContact NZ-OE1 3.07Å; K353-E357 WeakPolarHBondContact O-CB 3.49Å; K353-E357 WeakPolarHBondContact O-CG 3.36Å; K353-E357 PolarHBondContact O-N 2.97Å
354L90.3Very high88.7Confident5 Ų552.3 Ų52.33%0.02625%0.254CS..Hα-helixtrans-57.4-48.5176.4-178.570000111.6I285 T290 L293 L314 R350 F351 K356 E357 A358I285-L354 HydrophobicContact CG2-CD2 4.18Å; T290-L354 HydrophobicContact CG2-CD1 3.98Å; L293-L354 HydrophobicContact CD1-CD1 4.13Å; L314-L354 HydrophobicContact CD1-CD2 3.93Å; R350-L354 PolarHBondContact O-N 3.43Å; R350-L354 VanDerWaalsContact O-N 3.09Å; F351-L354 HydrophobicContact CD1-CD2 3.89Å; F351-L354 HydrophobicContact CE1-CD2 4.32Å; F351-L354 PolarHBondContact O-N 3.09Å; L354-K356 VanDerWaalsContact C-N 3.34Å; L354-K356 PolarHBondContact O-N 2.76Å; L354-E357 PolarHBondContact O-N 3.09Å; L354-A358 WeakPolarHBondContact O-CB 3.32Å; L354-A358 PolarHBondContact O-N 3.08Å
355V91.3Very high89Confident0 Ų052.2 Ų52.20%025%0.254CS..Hα-helixtrans-65.1-39.6-179.3172.60000111.8L314 F351 S352 K353 F359 Q360 F365 L366L314-V355 HydrophobicContact CD2-CG2 3.94Å; F351-V355 WeakPolarHBondContact O-CG2 3.44Å; F351-V355 PolarHBondContact O-N 2.97Å; S352-V355 PolarHBondContact O-N 3.24Å; K353-V355 PolarHBondContact O-N 3.27Å; V355-F359 HydrophobicContact CB-CD2 4.49Å; V355-F359 HydrophobicContact CG1-CB 4.48Å; V355-F359 HydrophobicContact CG1-CD2 4.49Å; V355-F359 HydrophobicContact CG2-CD2 4.33Å; V355-F359 CarbonylContact O-C 3.6Å; V355-F359 WeakPolarHBondContact O-CA 3.2Å; V355-F359 WeakPolarHBondContact O-CB 3.34Å; V355-F359 PolarHBondContact O-N 3.14Å; V355-Q360 PolarHBondContact O-N 3.47Å; V355-F365 HydrophobicContact CG1-CB 3.94Å; V355-L366 HydrophobicContact CG1-CD2 3.83Å; V355-L366 HydrophobicContact CG1-CG 4.26Å
356K91.4Very high89.3Confident133 Ų13353.8 Ų53.858%0.57826%0.261SS*.Hα-helixtrans-62.2-47.9176.5-178.8170.6-177178.50112.5S352 K353 L354 Q360 D361S352-K356 WeakPolarHBondContact O-CB 3.44Å; S352-K356 PolarHBondContact O-N 2.88Å; K353-K356 PolarHBondContact O-N 3.31Å; L354-K356 VanDerWaalsContact C-N 3.34Å; L354-K356 PolarHBondContact O-N 2.76Å; K356-Q360 WeakPolarHBondContact O-CA 3.28Å; K356-Q360 PolarHBondContact O-N 3.43Å; K356-D361 VanDerWaalsContact CA-OD1 3.32Å; K356-D361 WeakPolarHBondContact CA-OD1 3.25Å; K356-D361 WeakPolarHBondContact CB-OD1 3.36Å
357E90.8Very high89.4Confident95 Ų9552.9 Ų52.944%0.44426%0.256SS..Hα-helixtrans-78.1-41.5-175.7-69.4178.3178.900112.8T290 K353 L354T290-E357 HydrophobicContact CG2-CB 3.71Å; K353-E357 WeakPolarHBondContact CE-OE1 3.41Å; K353-E357 HydrophobicContact CG-CG 4.41Å; K353-E357 IonicContact NZ-OE1 3.07Å; K353-E357 WeakPolarHBondContact O-CB 3.49Å; K353-E357 WeakPolarHBondContact O-CG 3.36Å; K353-E357 PolarHBondContact O-N 2.97Å; L354-E357 PolarHBondContact O-N 3.09Å
358A89.9Confident89.5Confident0 Ų052.8 Ų52.80%026%0.256CS..Hα-helixtrans-83.5-37.4-17700000113.3T290 L293 H294 L354T290-A358 HydrophobicContact CG2-CB 4.38Å; L293-A358 HydrophobicContact CB-CB 3.72Å; L293-A358 HydrophobicContact CD1-CB 4.05Å; H294-A358 WeakPolarHBondContact CA-O 3.33Å; H294-A358 WeakPolarHBondContact CB-O 3.38Å; H294-A358 PolarHBondContact ND1-O 3.27Å; L354-A358 WeakPolarHBondContact O-CB 3.32Å; L354-A358 PolarHBondContact O-N 3.08Å
359F90.9Very high89.6Confident1 Ų152.9 Ų52.90%0.00426%0.256CS..Hα-helixtrans-120.410.1-169.7-51.6-61.6000113.6L293 F297 M310 L314 V355 D361 D362 F365L293-F359 HydrophobicContact CB-CE1 4.43Å; L293-F359 HydrophobicContact CB-CZ 4.46Å; F297-F359 HydrophobicContact CB-CD1 3.89Å; F297-F359 HydrophobicContact CB-CE1 4.2Å; F297-F359 HydrophobicContact CD2-CD1 4.23Å; F297-F359 HydrophobicContact CG-CD1 4.01Å; M310-F359 HydrophobicContact CE-CD1 4.48Å; M310-F359 HydrophobicContact CE-CE1 3.59Å; M310-F359 HydrophobicContact CE-CZ 4.32Å; L314-F359 HydrophobicContact CD2-CE2 4.13Å; V355-F359 HydrophobicContact CB-CD2 4.49Å; V355-F359 HydrophobicContact CG1-CB 4.48Å; V355-F359 HydrophobicContact CG1-CD2 4.49Å; V355-F359 HydrophobicContact CG2-CD2 4.33Å; V355-F359 CarbonylContact O-C 3.6Å; V355-F359 WeakPolarHBondContact O-CA 3.2Å; V355-F359 WeakPolarHBondContact O-CB 3.34Å; V355-F359 PolarHBondContact O-N 3.14Å; F359-D361 PolarHBondContact O-N 3.02Å; F359-D362 WeakPolarHBondContact O-CB 3.34Å; F359-D362 PolarHBondContact O-N 3.3Å; F359-F365 HydrophobicContact CB-CB 4.16Å; F359-F365 HydrophobicContact CB-CD1 4.4Å; F359-F365 HydrophobicContact CB-CD2 3.91Å; F359-F365 HydrophobicContact CB-CE2 4.4Å; F359-F365 HydrophobicContact CB-CG 3.89Å; F359-F365 HydrophobicContact CD1-CD1 4.01Å; F359-F365 HydrophobicContact CD1-CD2 4.15Å; F359-F365 AromaticContact CD1-CE1 3.73Å; F359-F365 HydrophobicContact CD1-CE1 3.73Å; F359-F365 AromaticContact CD1-CE2 3.87Å; F359-F365 HydrophobicContact CD1-CE2 3.87Å; F359-F365 HydrophobicContact CD1-CG 4.21Å; F359-F365 AromaticContact CD1-CZ 3.64Å; F359-F365 HydrophobicContact CD1-CZ 3.64Å; F359-F365 HydrophobicContact CD2-CB 4.15Å; F359-F365 AromaticContact CD2-CD1 3.46Å; F359-F365 HydrophobicContact CD2-CD1 3.46Å; F359-F365 VanDerWaalsContact CD2-CD1 3.46Å; F359-F365 HydrophobicContact CD2-CD2 4.46Å; F359-F365 AromaticContact CD2-CE1 3.91Å; F359-F365 HydrophobicContact CD2-CE1 3.91Å; F359-F365 AromaticContact CD2-CG 3.77Å; F359-F365 HydrophobicContact CD2-CG 3.77Å; F359-F365 HydrophobicContact CE1-CD1 4.15Å; F359-F365 AromaticContact CE1-CE1 3.57Å; F359-F365 HydrophobicContact CE1-CE1 3.57Å; F359-F365 HydrophobicContact CE1-CE2 4.4Å; F359-F365 AromaticContact CE1-CZ 3.7Å; F359-F365 HydrophobicContact CE1-CZ 3.7Å; F359-F365 AromaticContact CE2-CD1 3.63Å; F359-F365 HydrophobicContact CE2-CD1 3.63Å; F359-F365 AromaticContact CE2-CE1 3.77Å; F359-F365 HydrophobicContact CE2-CE1 3.77Å; F359-F365 HydrophobicContact CE2-CG 4.4Å; F359-F365 HydrophobicContact CG-CB 4.28Å; F359-F365 AromaticContact CG-CD1 3.69Å; F359-F365 HydrophobicContact CG-CD1 3.69Å; F359-F365 AromaticContact CG-CD2 3.92Å; F359-F365 HydrophobicContact CG-CD2 3.92Å; F359-F365 AromaticContact CG-CE1 3.91Å; F359-F365 HydrophobicContact CG-CE1 3.91Å; F359-F365 HydrophobicContact CG-CE2 4.12Å; F359-F365 AromaticContact CG-CG 3.68Å; F359-F365 HydrophobicContact CG-CG 3.68Å; F359-F365 HydrophobicContact CG-CZ 4.12Å; F359-F365 AromaticContact CZ-CD1 3.98Å; F359-F365 HydrophobicContact CZ-CD1 3.98Å; F359-F365 AromaticContact CZ-CE1 3.59Å; F359-F365 HydrophobicContact CZ-CE1 3.59Å; F359-F365 HydrophobicContact CZ-CZ 4.22Å
360Q89.6Confident89.4Confident130 Ų13050.3 Ų50.361%0.60724%0.242SC*.THydrogen-bonded Turntrans52.537.6176.5-62.4-178.2-20.900114H294 V355 K356 D362H294-Q360 PolarHBondContact CE1-NE2 2.98Å; H294-Q360 PolarHBondContact NE2-NE2 3.08Å; V355-Q360 PolarHBondContact O-N 3.47Å; K356-Q360 WeakPolarHBondContact O-CA 3.28Å; K356-Q360 PolarHBondContact O-N 3.43Å; Q360-D362 PolarHBondContact O-N 3Å
361D89.6Confident88.8Confident70 Ų7052.7 Ų52.737%0.37426%0.255SS..THydrogen-bonded Turntrans57.433.4-177-66.7-40.3000113.7K356 F359 L366K356-D361 VanDerWaalsContact CA-OD1 3.32Å; K356-D361 WeakPolarHBondContact CA-OD1 3.25Å; K356-D361 WeakPolarHBondContact CB-OD1 3.36Å; F359-D361 PolarHBondContact O-N 3.02Å; D361-L366 HydrophobicContact CB-CD1 4.32Å; D361-L366 WeakPolarHBondContact O-CD1 3.5Å
362D90.7Very high88.3Confident24 Ų2458.1 Ų58.113%0.12828%0.278CS..  trans-55.5129174.9179.2-76.2000111.1F297 F359 Q360 R364 F365 L366F297-D362 HydrophobicContact CZ-CB 4.09Å; F359-D362 WeakPolarHBondContact O-CB 3.34Å; F359-D362 PolarHBondContact O-N 3.3Å; Q360-D362 PolarHBondContact O-N 3Å; D362-R364 PolarHBondContact O-N 3.02Å; D362-R364 VanDerWaalsContact O-N 3.09Å; D362-R364 WeakPolarHBondContact OD1-CA 3.39Å; D362-R364 WeakPolarHBondContact OD1-CB 3.19Å; D362-R364 WeakPolarHBondContact OD1-CG 3.43Å; D362-R364 IonicContact OD1-CZ 3.22Å; D362-R364 PolarHBondContact OD1-N 3.2Å; D362-R364 IonicContact OD1-NE 2.87Å; D362-R364 PolarHBondContact OD1-NE 3.23Å; D362-R364 IonicContact OD1-NH2 3.95Å; D362-R364 IonicContact OD2-CZ 2.89Å; D362-R364 IonicContact OD2-NE 2.87Å; D362-R364 PolarHBondContact OD2-NE 3.15Å; D362-R364 IonicContact OD2-NH2 2.59Å; D362-R364 PolarHBondContact OD2-NH2 3.35Å; D362-F365 HydrophobicContact CB-CD2 3.96Å; D362-F365 PolarHBondContact O-N 3.4Å; D362-F365 VanDerWaalsContact O-N 3.09Å; D362-L366 PolarHBondContact O-N 2.75Å
363P90.2Very high87.9Confident91 Ų9157 Ų5759%0.59127%0.271SS*.Hα-helixtrans-57.5-28.1-175.5-27.834.9000114.9T367P363-T367 VanDerWaalsContact O-CB 3.32Å; P363-T367 WeakPolarHBondContact O-CB 3.46Å; P363-T367 PolarHBondContact O-N 3.44Å; P363-T367 PolarHBondContact O-OG1 2.94Å
364R90.7Very high87.5Confident103 Ų10351 Ų5139%0.38925%0.245SC..Hα-helixtrans-70.6-44.1179.3-57.4168-77.5-167.7-0.5110D301 I307 L311 D362 T367 A368D301-R364 IonicContact OD1-CZ 3.61Å; D301-R364 IonicContact OD1-NH1 3.42Å; D301-R364 PolarHBondContact OD1-NH1 3.49Å; D301-R364 IonicContact OD1-NH2 3.28Å; D301-R364 PolarHBondContact OD1-NH2 2.9Å; I307-R364 VanDerWaalsContact CD1-CZ 3.42Å; L311-R364 HydrophobicContact CD1-CB 4.15Å; L311-R364 HydrophobicContact CD2-CB 4.07Å; D362-R364 PolarHBondContact O-N 3.02Å; D362-R364 VanDerWaalsContact O-N 3.09Å; D362-R364 WeakPolarHBondContact OD1-CA 3.39Å; D362-R364 WeakPolarHBondContact OD1-CB 3.19Å; D362-R364 WeakPolarHBondContact OD1-CG 3.43Å; D362-R364 IonicContact OD1-CZ 3.22Å; D362-R364 PolarHBondContact OD1-N 3.2Å; D362-R364 IonicContact OD1-NE 2.87Å; D362-R364 PolarHBondContact OD1-NE 3.23Å; D362-R364 IonicContact OD1-NH2 3.95Å; D362-R364 IonicContact OD2-CZ 2.89Å; D362-R364 IonicContact OD2-NE 2.87Å; D362-R364 PolarHBondContact OD2-NE 3.15Å; D362-R364 IonicContact OD2-NH2 2.59Å; D362-R364 PolarHBondContact OD2-NH2 3.35Å; R364-T367 PolarHBondContact O-N 2.85Å; R364-A368 WeakPolarHBondContact O-CB 3.21Å; R364-A368 PolarHBondContact O-N 2.95Å
365F89.5Confident87.2Confident0 Ų055 Ų550%026%0.262CS..Hα-helixtrans-70.1-37.6176.8-74.1-87.6000112.5F297 I307 M310 L311 L314 V355 F359 D362 T367 A368 R369F297-F365 AromaticContact CD2-CE2 3.61Å; F297-F365 HydrophobicContact CD2-CE2 3.61Å; F297-F365 HydrophobicContact CD2-CZ 4.11Å; F297-F365 HydrophobicContact CE2-CD2 4.32Å; F297-F365 AromaticContact CE2-CE2 3.63Å; F297-F365 HydrophobicContact CE2-CE2 3.63Å; I307-F365 HydrophobicContact CG2-CE2 3.59Å; I307-F365 HydrophobicContact CG2-CZ 3.7Å; M310-F365 HydrophobicContact CB-CE1 4.18Å; M310-F365 HydrophobicContact CB-CZ 4.04Å; M310-F365 HydrophobicContact CE-CZ 4.15Å; L311-F365 HydrophobicContact CD2-CB 4.3Å; L311-F365 HydrophobicContact CD2-CD1 3.6Å; L311-F365 HydrophobicContact CD2-CD2 3.88Å; L311-F365 HydrophobicContact CD2-CE1 3.79Å; L311-F365 HydrophobicContact CD2-CE2 4.06Å; L311-F365 HydrophobicContact CD2-CG 3.67Å; L311-F365 HydrophobicContact CD2-CZ 4.02Å; L311-F365 HydrophobicContact CG-CE1 4.44Å; L311-F365 HydrophobicContact CG-CZ 4.5Å; L314-F365 HydrophobicContact CD2-CD1 3.72Å; V355-F365 HydrophobicContact CG1-CB 3.94Å; F359-F365 HydrophobicContact CB-CB 4.16Å; F359-F365 HydrophobicContact CB-CD1 4.4Å; F359-F365 HydrophobicContact CB-CD2 3.91Å; F359-F365 HydrophobicContact CB-CE2 4.4Å; F359-F365 HydrophobicContact CB-CG 3.89Å; F359-F365 HydrophobicContact CD1-CD1 4.01Å; F359-F365 HydrophobicContact CD1-CD2 4.15Å; F359-F365 AromaticContact CD1-CE1 3.73Å; F359-F365 HydrophobicContact CD1-CE1 3.73Å; F359-F365 AromaticContact CD1-CE2 3.87Å; F359-F365 HydrophobicContact CD1-CE2 3.87Å; F359-F365 HydrophobicContact CD1-CG 4.21Å; F359-F365 AromaticContact CD1-CZ 3.64Å; F359-F365 HydrophobicContact CD1-CZ 3.64Å; F359-F365 HydrophobicContact CD2-CB 4.15Å; F359-F365 AromaticContact CD2-CD1 3.46Å; F359-F365 HydrophobicContact CD2-CD1 3.46Å; F359-F365 VanDerWaalsContact CD2-CD1 3.46Å; F359-F365 HydrophobicContact CD2-CD2 4.46Å; F359-F365 AromaticContact CD2-CE1 3.91Å; F359-F365 HydrophobicContact CD2-CE1 3.91Å; F359-F365 AromaticContact CD2-CG 3.77Å; F359-F365 HydrophobicContact CD2-CG 3.77Å; F359-F365 HydrophobicContact CE1-CD1 4.15Å; F359-F365 AromaticContact CE1-CE1 3.57Å; F359-F365 HydrophobicContact CE1-CE1 3.57Å; F359-F365 HydrophobicContact CE1-CE2 4.4Å; F359-F365 AromaticContact CE1-CZ 3.7Å; F359-F365 HydrophobicContact CE1-CZ 3.7Å; F359-F365 AromaticContact CE2-CD1 3.63Å; F359-F365 HydrophobicContact CE2-CD1 3.63Å; F359-F365 AromaticContact CE2-CE1 3.77Å; F359-F365 HydrophobicContact CE2-CE1 3.77Å; F359-F365 HydrophobicContact CE2-CG 4.4Å; F359-F365 HydrophobicContact CG-CB 4.28Å; F359-F365 AromaticContact CG-CD1 3.69Å; F359-F365 HydrophobicContact CG-CD1 3.69Å; F359-F365 AromaticContact CG-CD2 3.92Å; F359-F365 HydrophobicContact CG-CD2 3.92Å; F359-F365 AromaticContact CG-CE1 3.91Å; F359-F365 HydrophobicContact CG-CE1 3.91Å; F359-F365 HydrophobicContact CG-CE2 4.12Å; F359-F365 AromaticContact CG-CG 3.68Å; F359-F365 HydrophobicContact CG-CG 3.68Å; F359-F365 HydrophobicContact CG-CZ 4.12Å; F359-F365 AromaticContact CZ-CD1 3.98Å; F359-F365 HydrophobicContact CZ-CD1 3.98Å; F359-F365 AromaticContact CZ-CE1 3.59Å; F359-F365 HydrophobicContact CZ-CE1 3.59Å; F359-F365 HydrophobicContact CZ-CZ 4.22Å; D362-F365 HydrophobicContact CB-CD2 3.96Å; D362-F365 PolarHBondContact O-N 3.4Å; D362-F365 VanDerWaalsContact O-N 3.09Å; F365-T367 VanDerWaalsContact C-N 3.32Å; F365-T367 PolarHBondContact O-N 3.37Å; F365-A368 PolarHBondContact O-N 3.48Å; F365-R369 WeakPolarHBondContact O-CB 3.31Å; F365-R369 PolarHBondContact O-N 3.3Å
366L88.6Confident86.8Confident43 Ų4356.9 Ų56.923%0.22528%0.278CS..Hα-helixtrans-60.2-43.9170.6-67.7174.7000111.2V355 D361 D362 R369 D370V355-L366 HydrophobicContact CG1-CD2 3.83Å; V355-L366 HydrophobicContact CG1-CG 4.26Å; D361-L366 HydrophobicContact CB-CD1 4.32Å; D361-L366 WeakPolarHBondContact O-CD1 3.5Å; D362-L366 PolarHBondContact O-N 2.75Å; L366-R369 PolarHBondContact O-N 2.88Å; L366-D370 VanDerWaalsContact O-CB 3.28Å; L366-D370 WeakPolarHBondContact O-CB 3.41Å; L366-D370 PolarHBondContact O-N 3.42Å
367T88.6Confident86.4Confident64 Ų6450.6 Ų50.639%0.39325%0.25SS..Hα-helixtrans-64.1-42.4177.4-62.20000112.2P363 R364 F365 K371P363-T367 VanDerWaalsContact O-CB 3.32Å; P363-T367 WeakPolarHBondContact O-CB 3.46Å; P363-T367 PolarHBondContact O-N 3.44Å; P363-T367 PolarHBondContact O-OG1 2.94Å; R364-T367 PolarHBondContact O-N 2.85Å; F365-T367 VanDerWaalsContact C-N 3.32Å; F365-T367 PolarHBondContact O-N 3.37Å; T367-K371 HydrophobicContact CG2-CB 4.3Å; T367-K371 HydrophobicContact CG2-CD 3.99Å; T367-K371 HydrophobicContact CG2-CG 4.25Å; T367-K371 WeakPolarHBondContact O-CB 3.38Å; T367-K371 PolarHBondContact O-N 3.27Å
368A87.9Confident85.9Confident2 Ų246 Ų462%0.01723%0.229CC..Iπ-helixtrans-61.2-47.8176.500000111.8L311 E315 R364 F365 A373L311-A368 HydrophobicContact CB-CB 4.38Å; L311-A368 HydrophobicContact CD2-CB 3.9Å; E315-A368 HydrophobicContact CG-CB 3.82Å; E315-A368 WeakPolarHBondContact OE1-CB 3.15Å; R364-A368 WeakPolarHBondContact O-CB 3.21Å; R364-A368 PolarHBondContact O-N 2.95Å; F365-A368 PolarHBondContact O-N 3.48Å; A368-A373 PolarHBondContact O-N 2.83Å
369R87.8Confident85.5Confident22 Ų2247.5 Ų47.58%0.08324%0.237CC..Iπ-helixtrans-57.8-54.8173.7-176.4-163.771.4-160.7-3.8111.4I318 S352 F365 L366 Y374I318-R369 HydrophobicContact CD1-CB 4.15Å; I318-R369 HydrophobicContact CD1-CG 3.98Å; S352-R369 PolarHBondContact OG-NH1 3.41Å; F365-R369 WeakPolarHBondContact O-CB 3.31Å; F365-R369 PolarHBondContact O-N 3.3Å; L366-R369 PolarHBondContact O-N 2.88Å; R369-Y374 VanDerWaalsContact O-CB 3.25Å; R369-Y374 WeakPolarHBondContact O-CB 3.43Å; R369-Y374 PolarHBondContact O-N 2.73Å
370D82.7Confident84.7Confident26 Ų2649.1 Ų49.114%0.13925%0.246CC..Iπ-helixtrans-79.6-57.7-167.9-71.6-15.9000113.1L366 K375 Y444L366-D370 VanDerWaalsContact O-CB 3.28Å; L366-D370 WeakPolarHBondContact O-CB 3.41Å; L366-D370 PolarHBondContact O-N 3.42Å; D370-K375 PolarHBondContact O-N 3.47Å; D370-Y444 HydrophobicContact CB-CE1 3.75Å; D370-Y444 WeakPolarHBondContact CB-OH 3.37Å; D370-Y444 WeakPolarHBondContact O-CD1 3.41Å; D370-Y444 PolarHBondContact OD2-OH 2.79Å
371K77.1Confident83.5Confident145 Ų14544.1 Ų44.163%0.6323%0.227SC*.Iπ-helixtrans-78.7-26.8-169.2-69.3-166.1-175.1167.20113.5T367 K375T367-K371 HydrophobicContact CG2-CB 4.3Å; T367-K371 HydrophobicContact CG2-CD 3.99Å; T367-K371 HydrophobicContact CG2-CG 4.25Å; T367-K371 WeakPolarHBondContact O-CB 3.38Å; T367-K371 PolarHBondContact O-N 3.27Å; K371-K375 VanDerWaalsContact O-CB 3.27Å; K371-K375 WeakPolarHBondContact O-CB 3.29Å; K371-K375 WeakPolarHBondContact O-CD 3.31Å
372K77.3Confident82Confident116 Ų11645.3 Ų45.350%0.50424%0.236SC..Iπ-helixtrans-108.9-60.1-176-67.8179.3176.9-179.30111.6E315 A376E315-K372 VanDerWaalsContact CD-NZ 3.33Å; E315-K372 HydrophobicContact CG-CB 4.25Å; E315-K372 HydrophobicContact CG-CD 4.28Å; E315-K372 WeakPolarHBondContact OE1-CD 3.17Å; E315-K372 IonicContact OE1-NZ 2.79Å; E315-K372 PolarHBondContact OE1-NZ 2.89Å; E315-K372 WeakPolarHBondContact OE2-CD 3.14Å; E315-K372 IonicContact OE2-NZ 2.7Å; E315-K372 PolarHBondContact OE2-NZ 3.4Å; K372-A376 WeakPolarHBondContact O-CB 3.44Å; K372-A376 PolarHBondContact O-N 2.95Å
373A80.2Confident80.4Confident0 Ų045.9 Ų45.90%024%0.239CC..Iπ-helixtrans-72.5-57.2-171.800000112.8I318 I319 A368 K375 A376 V377I318-A373 HydrophobicContact CB-CB 3.69Å; I318-A373 HydrophobicContact CD1-CB 4.1Å; I318-A373 HydrophobicContact CG2-CB 3.57Å; I319-A373 HydrophobicContact CG1-CB 4.07Å; A368-A373 PolarHBondContact O-N 2.83Å; A373-K375 VanDerWaalsContact C-N 3.34Å; A373-K375 PolarHBondContact O-N 3.44Å; A373-A376 WeakPolarHBondContact O-CB 3.36Å; A373-A376 PolarHBondContact O-N 3.43Å; A373-V377 WeakPolarHBondContact O-CG2 3.4Å; A373-V377 PolarHBondContact O-N 3.3Å
374Y82.1Confident78.9Confident2 Ų242.1 Ų42.11%0.00821%0.213CC..Iπ-helixtrans-65.6-39.7-177.6-156.5-104.1000111.7L344 L347 F348 R369 A376 V377 V378 V441 Y444L344-Y374 PolarHBondContact O-OH 3.05Å; L347-Y374 HydrophobicContact CD2-CE2 4.39Å; F348-Y374 HydrophobicContact CB-CD2 4.44Å; F348-Y374 HydrophobicContact CB-CE2 3.61Å; F348-Y374 HydrophobicContact CD2-CD1 4.13Å; F348-Y374 AromaticContact CD2-CD2 3.94Å; F348-Y374 HydrophobicContact CD2-CD2 3.94Å; F348-Y374 AromaticContact CD2-CE1 3.99Å; F348-Y374 HydrophobicContact CD2-CE1 3.99Å; F348-Y374 AromaticContact CD2-CE2 3.82Å; F348-Y374 HydrophobicContact CD2-CE2 3.82Å; F348-Y374 HydrophobicContact CD2-CG 4.09Å; F348-Y374 AromaticContact CD2-CZ 3.84Å; F348-Y374 HydrophobicContact CG-CE2 4.2Å; R369-Y374 VanDerWaalsContact O-CB 3.25Å; R369-Y374 WeakPolarHBondContact O-CB 3.43Å; R369-Y374 PolarHBondContact O-N 2.73Å; Y374-A376 VanDerWaalsContact C-N 3.32Å; Y374-A376 PolarHBondContact O-N 2.85Å; Y374-V377 PolarHBondContact O-N 2.73Å; Y374-V378 HydrophobicContact CD1-CG2 3.92Å; Y374-V378 HydrophobicContact CE1-CG2 3.76Å; Y374-V378 WeakPolarHBondContact O-CB 3.12Å; Y374-V378 VanDerWaalsContact O-CG2 3.27Å; Y374-V378 WeakPolarHBondContact O-CG2 3.42Å; Y374-V378 PolarHBondContact O-N 2.81Å; Y374-V441 HydrophobicContact CE1-CG1 4.21Å; Y374-V441 HydrophobicContact CE1-CG2 4.13Å; Y374-Y444 AromaticContact CD1-CD2 3.66Å; Y374-Y444 HydrophobicContact CD1-CD2 3.66Å; Y374-Y444 HydrophobicContact CD1-CE2 4.17Å; Y374-Y444 HydrophobicContact CD1-CG 4.22Å; Y374-Y444 HydrophobicContact CE1-CD2 4.14Å
375K84.5Confident77.4Confident87 Ų8742.6 Ų42.638%0.37822%0.218SC..Hα-helixtrans-57.9-41.1169.8-171.3175.4-175.6-178.80112.4D370 K371 A373 N379D370-K375 PolarHBondContact O-N 3.47Å; K371-K375 VanDerWaalsContact O-CB 3.27Å; K371-K375 WeakPolarHBondContact O-CB 3.29Å; K371-K375 WeakPolarHBondContact O-CD 3.31Å; A373-K375 VanDerWaalsContact C-N 3.34Å; A373-K375 PolarHBondContact O-N 3.44Å; K375-N379 WeakPolarHBondContact CG-ND2 3.34Å; K375-N379 WeakPolarHBondContact O-CB 3.4Å; K375-N379 PolarHBondContact O-N 3.2Å; K375-N379 PolarHBondContact O-ND2 2.96Å
376A83.2Confident75.7Confident41 Ų4143 Ų4334%0.33922%0.22SC..Hα-helixtrans-65.7-46.4177.200000111.4I319 K372 A373 Y374 V378 N379 D380I319-A376 HydrophobicContact CD1-CB 3.91Å; I319-A376 HydrophobicContact CG1-CB 4.06Å; K372-A376 WeakPolarHBondContact O-CB 3.44Å; K372-A376 PolarHBondContact O-N 2.95Å; A373-A376 WeakPolarHBondContact O-CB 3.36Å; A373-A376 PolarHBondContact O-N 3.43Å; Y374-A376 VanDerWaalsContact C-N 3.32Å; Y374-A376 PolarHBondContact O-N 2.85Å; A376-V378 PolarHBondContact O-N 2.75Å; A376-N379 PolarHBondContact O-N 2.95Å; A376-D380 WeakPolarHBondContact O-CB 3.27Å; A376-D380 PolarHBondContact O-N 3.15Å
377V82.1Confident74.1Confident0 Ų047.5 Ų47.50%024%0.24CC..Hα-helixtrans-60.9-47.2179.3176.20000111.9I319 M326 L344 L347 A373 Y374 N379 D380I319-V377 HydrophobicContact CB-CG2 4.49Å; I319-V377 HydrophobicContact CG1-CG2 4.39Å; M326-V377 HydrophobicContact SD-CG1 3.49Å; M326-V377 WeakPolarHBondContact SD-CG1 3.44Å; L344-V377 HydrophobicContact CD2-CG1 4.19Å; L347-V377 HydrophobicContact CD2-CG1 4.11Å; A373-V377 WeakPolarHBondContact O-CG2 3.4Å; A373-V377 PolarHBondContact O-N 3.3Å; Y374-V377 PolarHBondContact O-N 2.73Å; V377-N379 VanDerWaalsContact C-N 3.34Å; V377-N379 PolarHBondContact O-N 3.42Å; V377-D380 WeakPolarHBondContact O-CB 3.41Å; V377-D380 PolarHBondContact O-N 3.41Å
378V81.1Confident72.6Confident0 Ų044.8 Ų44.80%022%0.223CC..Hα-helixtrans-66.3-35.5-177.6169.30000112.4Y374 A376 S403 C405 V441 V445Y374-V378 HydrophobicContact CD1-CG2 3.92Å; Y374-V378 HydrophobicContact CE1-CG2 3.76Å; Y374-V378 WeakPolarHBondContact O-CB 3.12Å; Y374-V378 VanDerWaalsContact O-CG2 3.27Å; Y374-V378 WeakPolarHBondContact O-CG2 3.42Å; Y374-V378 PolarHBondContact O-N 2.81Å; A376-V378 PolarHBondContact O-N 2.75Å; V378-S403 PolarHBondContact O-OG 3.46Å; V378-C405 WeakPolarHBondContact O-CB 3.3Å; V378-V441 HydrophobicContact CG1-CG1 4.22Å; V378-V441 HydrophobicContact CG2-CG1 3.88Å; V378-V445 HydrophobicContact CG1-CB 4.46Å; V378-V445 HydrophobicContact CG1-CG2 3.5Å
379N81Confident70.9Confident30 Ų3046.8 Ų46.816%0.1624%0.236CC..THydrogen-bonded Turntrans-95.45.5-179.6-61.2-68.3000113.1K375 A376 V377 A381 Y444 Q446K375-N379 WeakPolarHBondContact CG-ND2 3.34Å; K375-N379 WeakPolarHBondContact O-CB 3.4Å; K375-N379 PolarHBondContact O-N 3.2Å; K375-N379 PolarHBondContact O-ND2 2.96Å; A376-N379 PolarHBondContact O-N 2.95Å; V377-N379 VanDerWaalsContact C-N 3.34Å; V377-N379 PolarHBondContact O-N 3.42Å; N379-A381 PolarHBondContact O-N 3.07Å; N379-Y444 PolarHBondContact ND2-O 3.34Å; N379-Q446 HydrophobicContact CB-CG 4.44Å; N379-Q446 WeakPolarHBondContact OD1-CB 3.27Å; N379-Q446 PolarHBondContact OD1-N 3.36Å
380D75Confident68.8Low36 Ų3648.3 Ų48.319%0.19325%0.245CC..  trans-66.8127.8178.2-171.8-90.2000110.4L323 A376 V377 T382L323-D380 HydrophobicContact CD2-CB 3.76Å; A376-D380 WeakPolarHBondContact O-CB 3.27Å; A376-D380 PolarHBondContact O-N 3.15Å; V377-D380 WeakPolarHBondContact O-CB 3.41Å; V377-D380 PolarHBondContact O-N 3.41Å; D380-T382 WeakPolarHBondContact OD1-CA 3.46Å; D380-T382 VanDerWaalsContact OD1-CB 3.26Å; D380-T382 WeakPolarHBondContact OD1-CB 3.27Å; D380-T382 PolarHBondContact OD1-N 3.1Å; D380-T382 PolarHBondContact OD1-OG1 2.94Å
381A63.2Low67Low25 Ų2554.8 Ų54.821%0.20727%0.272CS..  trans-105.714.5-178.800000112.1N379 K385 P401N379-A381 PolarHBondContact O-N 3.07Å; A381-K385 WeakPolarHBondContact O-CE 3.4Å; A381-K385 WeakPolarHBondContact O-CG 3.39Å; A381-P401 WeakPolarHBondContact CB-O 3.27Å
382T59.3Low65.5Low94 Ų9455.7 Ų55.758%0.57728%0.278SS*.SBendtrans-83.2-34.9-179.770.20000111.8D380D380-T382 WeakPolarHBondContact OD1-CA 3.46Å; D380-T382 VanDerWaalsContact OD1-CB 3.26Å; D380-T382 WeakPolarHBondContact OD1-CB 3.27Å; D380-T382 PolarHBondContact OD1-N 3.1Å; D380-T382 PolarHBondContact OD1-OG1 2.94Å
383I57.1Low63.6Low37 Ų3760.8 Ų60.819%0.1930%0.3CS..SBendtrans-95.4-58-173.8-51172.1000111.8L323 M326 V327 A330L323-I383 HydrophobicContact CB-CD1 4.21Å; L323-I383 HydrophobicContact CD2-CD1 3.71Å; L323-I383 WeakPolarHBondContact O-CD1 3.42Å; M326-I383 HydrophobicContact CB-CD1 3.55Å; V327-I383 HydrophobicContact CG2-CD1 3.58Å; V327-I383 HydrophobicContact CG2-CG1 3.79Å; V327-I383 HydrophobicContact CG2-CG2 4.45Å; A330-I383 HydrophobicContact CB-CG2 4.39Å
384F58.3Low61.7Low12 Ų1264.5 Ų64.55%0.05334%0.339CS..SBendtrans-112.193.6-178.4-58.9-70.1000110.9M326 A330 I333 T334 Y340 K404M326-F384 HydrophobicContact CB-CE2 4.28Å; M326-F384 HydrophobicContact CE-CD2 3.94Å; M326-F384 HydrophobicContact CE-CE2 4.05Å; A330-F384 HydrophobicContact CB-CE1 4.34Å; A330-F384 HydrophobicContact CB-CZ 4.17Å; I333-F384 HydrophobicContact CB-CE1 3.95Å; I333-F384 HydrophobicContact CB-CZ 3.69Å; I333-F384 HydrophobicContact CD1-CE2 4.24Å; I333-F384 HydrophobicContact CD1-CZ 3.82Å; I333-F384 HydrophobicContact CG1-CZ 4.36Å; I333-F384 HydrophobicContact CG2-CD1 4.08Å; I333-F384 HydrophobicContact CG2-CE1 3.3Å; I333-F384 HydrophobicContact CG2-CE2 3.89Å; I333-F384 HydrophobicContact CG2-CZ 3.19Å; T334-F384 HydrophobicContact CG2-CD1 4.44Å; T334-F384 HydrophobicContact CG2-CE1 4.16Å; Y340-F384 HydrophobicContact CD2-CD2 4.24Å; Y340-F384 AromaticContact CD2-CE2 3.88Å; Y340-F384 HydrophobicContact CD2-CE2 3.88Å; Y340-F384 HydrophobicContact CD2-CZ 4.41Å; Y340-F384 AromaticContact CE2-CD2 3.48Å; Y340-F384 HydrophobicContact CE2-CD2 3.48Å; Y340-F384 VanDerWaalsContact CE2-CD2 3.48Å; Y340-F384 AromaticContact CE2-CE2 3.44Å; Y340-F384 HydrophobicContact CE2-CE2 3.44Å; Y340-F384 VanDerWaalsContact CE2-CE2 3.44Å; Y340-F384 HydrophobicContact CE2-CG 4.42Å; Y340-F384 HydrophobicContact CE2-CZ 4.36Å; F384-K404 HydrophobicContact CB-CB 3.94Å; F384-K404 WeakPolarHBondContact O-CB 3.46Å; F384-K404 PolarHBondContact O-N 3.35Å
385K58.2Low59.6Low113 Ų11369.2 Ų69.249%0.49137%0.367SS..EExtended strand (participates in β ladder)trans-86.3132.4-177.8-67.1177.6-178.6175.40111.5A381 P401 E402A381-K385 WeakPolarHBondContact O-CE 3.4Å; A381-K385 WeakPolarHBondContact O-CG 3.39Å; K385-P401 HydrophobicContact CB-CB 3.9Å; K385-P401 HydrophobicContact CD-CB 3.84Å; K385-P401 HydrophobicContact CD-CG 4.04Å; K385-P401 HydrophobicContact CG-CB 3.76Å; K385-P401 HydrophobicContact CG-CG 4.35Å; K385-E402 CarbonylContact C-O 3.6Å
386L53.6Low57.5Low8 Ų869.1 Ų69.14%0.04239%0.391CS..EExtended strand (participates in β ladder)trans-105.5113.2162.7-179.466.3000107.5L388 E402 K404 V450L386-L388 HydrophobicContact CD2-CD2 4.08Å; L386-L388 HydrophobicContact CD2-CG 4.39Å; L386-L388 HydrophobicContact CG-CD2 4.24Å; L386-L388 HydrophobicContact CG-CG 4.39Å; L386-E402 PolarHBondContact N-O 2.76Å; L386-E402 PolarHBondContact O-N 3.35Å; L386-K404 HydrophobicContact CB-CB 4.17Å; L386-K404 HydrophobicContact CB-CG 4.39Å; L386-V450 HydrophobicContact CD2-CG1 3.94Å; L386-V450 HydrophobicContact CD2-CG2 4.46Å
387E56.8Low55.7Low138 Ų13870.4 Ų70.465%0.64539%0.391SS*.  trans-93.4111.8170.8-66.1-169.9168.600108.5P389E387-P389 WeakPolarHBondContact O-CD 3.39Å
388L55.3Low53.8Low7 Ų780.3 Ų80.34%0.03743%0.434CS..  trans-85.4117173.6-68.1174.3000108.8L386 M390 T399 N705 I708 V709L386-L388 HydrophobicContact CD2-CD2 4.08Å; L386-L388 HydrophobicContact CD2-CG 4.39Å; L386-L388 HydrophobicContact CG-CD2 4.24Å; L386-L388 HydrophobicContact CG-CG 4.39Å; L388-M390 PolarHBondContact O-N 3.38Å; L388-T399 PolarHBondContact O-OG1 3.16Å; L388-N705 HydrophobicContact CD2-CB 3.59Å; L388-I708 HydrophobicContact CD1-CG2 4.42Å; L388-V709 HydrophobicContact CB-CG2 3.72Å; L388-V709 HydrophobicContact CD1-CG2 4.13Å; L388-V709 HydrophobicContact CG-CG2 4.38Å
389P52.4Low52.4Low44 Ų4482 Ų8229%0.28644%0.444SS..  trans-67.8128.41800.79.1000110.8E387 E706E387-P389 WeakPolarHBondContact O-CD 3.39Å; P389-E706 HydrophobicContact CG-CG 4.43Å
390M45.3Very low51.1Low53 Ų5387.3 Ų87.326%0.26147%0.469SS..  trans-102.593.1162-96.9-174.3163.800108.4L388 Q392 T399 V709 I713 M753L388-M390 PolarHBondContact O-N 3.38Å; M390-Q392 PolarHBondContact O-N 3.2Å; M390-T399 HydrophobicContact CB-CG2 4.22Å; M390-T399 HydrophobicContact CG-CG2 4.08Å; M390-T399 HydrophobicContact SD-CG2 4.07Å; M390-V709 HydrophobicContact CE-CG1 3.83Å; M390-V709 HydrophobicContact CG-CG1 3.82Å; M390-I713 HydrophobicContact CE-CD1 4.27Å; M390-M753 HydrophobicContact CE-CE 4.28Å
391K44.6Very low50.2Low162 Ų16287.3 Ų87.370%0.70447%0.471SS*.  trans-86.390.4165.7-75.7-179.4-173.5156.30109.3E706K391-E706 IonicContact NZ-OE1 3.47Å
392Q44.4Very low50.5Low165 Ų16587 Ų8777%0.77146%0.464SS*.  trans-91.8134.1146.1-92.7-174-7.400107.8M390 G394M390-Q392 PolarHBondContact O-N 3.2Å; Q392-G394 PolarHBondContact O-N 3.34Å
393K37Very low51Low223 Ų22382.9 Ų82.997%0.9744%0.44SS*.THydrogen-bonded Turntrans-54.3109174.5-77.5-179.4174.3179.20109.1
394G40.3Very low51.9Low78 Ų7883.2 Ų83.280%0.80444%0.44SS*.THydrogen-bonded Turntrans127.5-13.3160.300000118.6Q392Q392-G394 PolarHBondContact O-N 3.34Å
395V38Very low53Low100 Ų10082.7 Ų82.761%0.60644%0.438SS*.  trans-140.5119.3176.7-169.50000110.3M397V395-M397 VanDerWaalsContact C-N 3.33Å; V395-M397 HydrophobicContact CB-CG 4.37Å; V395-M397 HydrophobicContact CB-SD 4.22Å; V395-M397 HydrophobicContact CG1-CG 3.97Å; V395-M397 HydrophobicContact CG1-SD 4.25Å; V395-M397 PolarHBondContact O-N 3.21Å
396G41.3Very low54.3Low86 Ų8677.4 Ų77.489%0.88742%0.415SS*.  trans-64.690.4172.200000110.4
397M46.2Very low55.8Low68 Ų6877.5 Ų77.534%0.33542%0.415SS..  trans-101.9113179.3-81.1160.278.200109.9V395 T399 K752V395-M397 VanDerWaalsContact C-N 3.33Å; V395-M397 HydrophobicContact CB-CG 4.37Å; V395-M397 HydrophobicContact CB-SD 4.22Å; V395-M397 HydrophobicContact CG1-CG 3.97Å; V395-M397 HydrophobicContact CG1-SD 4.25Å; V395-M397 PolarHBondContact O-N 3.21Å; M397-T399 PolarHBondContact O-N 2.96Å; M397-K752 VanDerWaalsContact CE-CE 3.46Å
398K42.1Very low57Low207 Ų20771.5 Ų71.590%0.939%0.387SS*.PPolyproline II helixtrans-71.8119.7169.4-64-176.4178.4-176.60109.2
399T50.1Low58.6Low35 Ų3571.1 Ų71.122%0.21539%0.386CS..PPolyproline II helixtrans-76.4153.8169.2370000110L388 M390 M397L388-T399 PolarHBondContact O-OG1 3.16Å; M390-T399 HydrophobicContact CB-CG2 4.22Å; M390-T399 HydrophobicContact CG-CG2 4.08Å; M390-T399 HydrophobicContact SD-CG2 4.07Å; M397-T399 PolarHBondContact O-N 2.96Å
400Q53.7Low60.3Low143 Ų14369 Ų6967%0.66837%0.372SS*.PPolyproline II helixtrans-65.4132.7171.2-75.6-72.7-1100108.8E402Q400-E402 PolarHBondContact O-N 2.93Å
401P57.7Low62.2Low36 Ų3668.3 Ų68.323%0.23437%0.369CS..PPolyproline II helixtrans-65.9133.8179.826.1-31.6000110.1A381 K385A381-P401 WeakPolarHBondContact CB-O 3.27Å; K385-P401 HydrophobicContact CB-CB 3.9Å; K385-P401 HydrophobicContact CD-CB 3.84Å; K385-P401 HydrophobicContact CD-CG 4.04Å; K385-P401 HydrophobicContact CG-CB 3.76Å; K385-P401 HydrophobicContact CG-CG 4.35Å
402E69.8Low64.3Low17 Ų1760.6 Ų60.68%0.07934%0.335CS..EExtended strand (participates in β ladder)trans-98.9163.7174.6-63.3-172.5176.600110.3K385 L386 Q400 K404 N447 R712 Q750K385-E402 CarbonylContact C-O 3.6Å; L386-E402 PolarHBondContact N-O 2.76Å; L386-E402 PolarHBondContact O-N 3.35Å; Q400-E402 PolarHBondContact O-N 2.93Å; E402-K404 PolarHBondContact O-N 2.8Å; E402-N447 PolarHBondContact OE2-ND2 3.01Å; E402-R712 IonicContact OE1-CZ 2.72Å; E402-R712 IonicContact OE1-NH1 3.94Å; E402-R712 PolarHBondContact OE1-NH1 2.71Å; E402-R712 IonicContact OE2-CZ 3.32Å; E402-R712 IonicContact OE2-NH1 2.94Å; E402-R712 PolarHBondContact OE2-NH1 2.87Å; E402-R712 IonicContact OE2-NH2 3.93Å; E402-R712 PolarHBondContact OE2-NH2 3.05Å; E402-Q750 PolarHBondContact OE1-NE2 3.25Å
403S69.4Low66.4Low9 Ų952.7 Ų52.76%0.06330%0.299CS..EExtended strand (participates in β ladder)trans-66131.5173.6171.90000110.2V378 C405 P406V378-S403 PolarHBondContact O-OG 3.46Å; S403-C405 PolarHBondContact O-N 2.73Å; S403-C405 WeakPolarHBondContact OG-CB 3.45Å; S403-C405 PolarHBondContact OG-N 3.37Å; S403-C405 VanDerWaalsContact OG-N 3.15Å; S403-P406 WeakPolarHBondContact O-CD 3.39Å
404K76.4Confident68.9Low44 Ų4442.8 Ų42.819%0.19126%0.256CS..SBendtrans-77.1-5.8172.3-160.4177.5179.2177.70112.8F384 L386 E402 P406 E407 L408F384-K404 HydrophobicContact CB-CB 3.94Å; F384-K404 WeakPolarHBondContact O-CB 3.46Å; F384-K404 PolarHBondContact O-N 3.35Å; L386-K404 HydrophobicContact CB-CB 4.17Å; L386-K404 HydrophobicContact CB-CG 4.39Å; E402-K404 PolarHBondContact O-N 2.8Å; K404-P406 VanDerWaalsContact C-N 3.35Å; K404-E407 WeakPolarHBondContact CE-OE2 3.11Å; K404-E407 HydrophobicContact CG-CB 4.29Å; K404-E407 WeakPolarHBondContact CG-OE2 3.49Å; K404-E407 PolarHBondContact O-N 2.83Å; K404-E407 VanDerWaalsContact O-N 3.14Å; K404-L408 HydrophobicContact CG-CG 4.33Å; K404-L408 PolarHBondContact O-N 2.98Å; K404-L408 VanDerWaalsContact O-N 3.12Å
405C80.1Confident71Confident0 Ų041.2 Ų41.20%023%0.229CC..Hα-helixtrans-49.3-45.2179.2-177.20000113.9Y340 V378 S403 E407 L408 L409Y340-C405 HydrophobicContact CE1-CB 4.21Å; Y340-C405 WeakPolarHBondContact OH-CB 3.46Å; V378-C405 WeakPolarHBondContact O-CB 3.3Å; S403-C405 PolarHBondContact O-N 2.73Å; S403-C405 WeakPolarHBondContact OG-CB 3.45Å; S403-C405 PolarHBondContact OG-N 3.37Å; S403-C405 VanDerWaalsContact OG-N 3.15Å; C405-E407 VanDerWaalsContact C-N 3.34Å; C405-E407 PolarHBondContact O-N 3.43Å; C405-L408 PolarHBondContact O-N 2.91Å; C405-L409 VanDerWaalsContact O-CG 3.27Å; C405-L409 WeakPolarHBondContact O-CG 3.18Å; C405-L409 PolarHBondContact O-N 2.7Å
406P85.5Confident73.3Confident3 Ų336.5 Ų36.52%0.01920%0.2CC..Hα-helixtrans-63.3-36.4-178.8-18.131.1000113.4S403 K404 A410 V445 V450 F451S403-P406 WeakPolarHBondContact O-CD 3.39Å; K404-P406 VanDerWaalsContact C-N 3.35Å; P406-A410 PolarHBondContact O-N 3.44Å; P406-A410 VanDerWaalsContact O-N 3.13Å; P406-V445 HydrophobicContact CB-CG1 4.16Å; P406-V445 HydrophobicContact CG-CG1 3.63Å; P406-V450 HydrophobicContact CB-CB 3.94Å; P406-V450 HydrophobicContact CB-CG1 4.04Å; P406-V450 HydrophobicContact CG-CB 4.48Å; P406-F451 HydrophobicContact CB-CB 4.05Å
407E84.7Confident75.6Confident9 Ų932.5 Ų32.54%0.04216%0.158CC..Hα-helixtrans-66.8-46.3175.2-175.8-163.5149.800110.5K404 C405 L409 A410 N411 Y454K404-E407 WeakPolarHBondContact CE-OE2 3.11Å; K404-E407 HydrophobicContact CG-CB 4.29Å; K404-E407 WeakPolarHBondContact CG-OE2 3.49Å; K404-E407 PolarHBondContact O-N 2.83Å; K404-E407 VanDerWaalsContact O-N 3.14Å; C405-E407 VanDerWaalsContact C-N 3.34Å; C405-E407 PolarHBondContact O-N 3.43Å; E407-L409 VanDerWaalsContact C-N 3.34Å; E407-L409 PolarHBondContact O-N 3.12Å; E407-A410 PolarHBondContact O-N 2.9Å; E407-N411 VanDerWaalsContact O-CG 3.27Å; E407-N411 PolarHBondContact O-N 2.97Å; E407-N411 PolarHBondContact O-ND2 3.32Å; E407-Y454 HydrophobicContact CB-CD2 4.32Å; E407-Y454 HydrophobicContact CB-CE2 4.31Å; E407-Y454 HydrophobicContact CG-CD1 4.1Å; E407-Y454 HydrophobicContact CG-CD2 4.1Å; E407-Y454 HydrophobicContact CG-CE1 3.93Å; E407-Y454 HydrophobicContact CG-CE2 3.96Å; E407-Y454 HydrophobicContact CG-CG 4.19Å
408L83.1Confident77.5Confident12 Ų1232.4 Ų32.46%0.06315%0.154CC..Hα-helixtrans-63.5-39.7179.9-65.5175.6000112Y340 K404 C405 N411 Y412Y340-L408 HydrophobicContact CD1-CB 3.81Å; Y340-L408 HydrophobicContact CD1-CD1 3.62Å; Y340-L408 HydrophobicContact CD1-CG 4.36Å; Y340-L408 HydrophobicContact CD2-CD1 4.28Å; Y340-L408 HydrophobicContact CE1-CB 4.11Å; Y340-L408 HydrophobicContact CE1-CD1 3.74Å; Y340-L408 HydrophobicContact CE2-CD1 4.36Å; Y340-L408 HydrophobicContact CG-CD1 3.88Å; K404-L408 HydrophobicContact CG-CG 4.33Å; K404-L408 PolarHBondContact O-N 2.98Å; K404-L408 VanDerWaalsContact O-N 3.12Å; C405-L408 PolarHBondContact O-N 2.91Å; L408-N411 PolarHBondContact O-N 3.14Å; L408-Y412 WeakPolarHBondContact O-CB 3.47Å; L408-Y412 PolarHBondContact O-N 3.35Å
409L87.8Confident79.3Confident0 Ų028.6 Ų28.60%014%0.138CC..Hα-helixtrans-62.3-44.2173.6-68.3169.5000111.2V341 C405 E407 N411 Y412 C413 V438 V441 V445 F451V341-L409 HydrophobicContact CG1-CD2 4.12Å; V341-L409 HydrophobicContact CG2-CD2 3.7Å; C405-L409 VanDerWaalsContact O-CG 3.27Å; C405-L409 WeakPolarHBondContact O-CG 3.18Å; C405-L409 PolarHBondContact O-N 2.7Å; E407-L409 VanDerWaalsContact C-N 3.34Å; E407-L409 PolarHBondContact O-N 3.12Å; L409-N411 PolarHBondContact O-N 3.28Å; L409-Y412 PolarHBondContact O-N 2.9Å; L409-C413 PolarHBondContact O-N 3.22Å; L409-C413 PolarHBondContact O-SG 3.26Å; L409-C413 VanDerWaalsContact O-SG 3.39Å; L409-V438 HydrophobicContact CB-CG1 4.37Å; L409-V438 HydrophobicContact CD2-CG1 4.03Å; L409-V441 HydrophobicContact CD1-CG1 4.1Å; L409-V441 HydrophobicContact CD2-CG1 4.33Å; L409-V445 HydrophobicContact CD1-CG2 3.92Å; L409-F451 HydrophobicContact CB-CD2 3.98Å; L409-F451 HydrophobicContact CB-CE2 4.1Å
410A89.1Confident80.6Confident0 Ų027.4 Ų27.40%013%0.13CC..Hα-helixtrans-64.6-39.4177.900000112.4P406 E407 C413 D414 F451 H455P406-A410 PolarHBondContact O-N 3.44Å; P406-A410 VanDerWaalsContact O-N 3.13Å; E407-A410 PolarHBondContact O-N 2.9Å; A410-C413 PolarHBondContact O-N 3.46Å; A410-D414 PolarHBondContact O-N 3.27Å; A410-F451 HydrophobicContact CB-CD2 3.76Å; A410-F451 HydrophobicContact CB-CE2 4Å; A410-F451 HydrophobicContact CB-CG 4.42Å; A410-H455 HydrophobicContact CB-CB 4.42Å
411N85.9Confident81.7Confident37 Ų3725.7 Ų25.720%0.19813%0.132CC..Hα-helixtrans-66-40175.4-69.5-23000111.9E407 L408 L409 D414 M415 H458E407-N411 VanDerWaalsContact O-CG 3.27Å; E407-N411 PolarHBondContact O-N 2.97Å; E407-N411 PolarHBondContact O-ND2 3.32Å; L408-N411 PolarHBondContact O-N 3.14Å; L409-N411 PolarHBondContact O-N 3.28Å; N411-D414 WeakPolarHBondContact O-CB 3.41Å; N411-D414 PolarHBondContact O-N 3.39Å; N411-M415 WeakPolarHBondContact O-CG 3.27Å; N411-M415 PolarHBondContact O-N 2.92Å; N411-H458 PolarHBondContact OD1-NE2 3.18Å
412Y87.2Confident82.5Confident0 Ų025.1 Ų25.10%013%0.126CC..Hα-helixtrans-65.4-42.7176-177.8-116.6000112E338 V341 L408 L409 D414 M415 L416 L422 V438E338-Y412 HydrophobicContact CB-CD2 4.04Å; E338-Y412 HydrophobicContact CB-CE2 3.85Å; E338-Y412 HydrophobicContact CG-CE2 3.91Å; V341-Y412 HydrophobicContact CB-CD1 3.8Å; V341-Y412 HydrophobicContact CB-CE1 4.04Å; V341-Y412 HydrophobicContact CB-CG 4.07Å; V341-Y412 HydrophobicContact CG1-CD1 3.59Å; V341-Y412 HydrophobicContact CG1-CE1 3.64Å; V341-Y412 HydrophobicContact CG1-CG 4.36Å; V341-Y412 HydrophobicContact CG2-CD1 3.93Å; V341-Y412 HydrophobicContact CG2-CG 3.93Å; L408-Y412 WeakPolarHBondContact O-CB 3.47Å; L408-Y412 PolarHBondContact O-N 3.35Å; L409-Y412 PolarHBondContact O-N 2.9Å; Y412-D414 VanDerWaalsContact C-N 3.31Å; Y412-D414 PolarHBondContact O-N 2.91Å; Y412-M415 WeakPolarHBondContact O-CB 3.31Å; Y412-M415 PolarHBondContact O-N 3.37Å; Y412-M415 VanDerWaalsContact O-N 3.14Å; Y412-L416 HydrophobicContact CD1-CD1 4.13Å; Y412-L416 HydrophobicContact CE1-CD1 3.68Å; Y412-L416 HydrophobicContact CE1-CG 4.39Å; Y412-L416 HydrophobicContact CE2-CD2 4.48Å; Y412-L416 HydrophobicContact CE2-CG 4.38Å; Y412-L416 PolarHBondContact O-N 2.62Å; Y412-L416 VanDerWaalsContact O-N 3.1Å; Y412-L422 HydrophobicContact CE2-CD2 4.4Å; Y412-V438 HydrophobicContact CD1-CG2 3.68Å; Y412-V438 HydrophobicContact CE1-CG2 3.8Å
413C90.2Very high82.9Confident0 Ų024.8 Ų24.80%013%0.126CC..Hα-helixtrans-56.7-43.3170.7-69.80000111.9L409 A410 M415 L416 L417 L435L409-C413 PolarHBondContact O-N 3.22Å; L409-C413 PolarHBondContact O-SG 3.26Å; L409-C413 VanDerWaalsContact O-SG 3.39Å; A410-C413 PolarHBondContact O-N 3.46Å; C413-M415 VanDerWaalsContact C-N 3.32Å; C413-M415 PolarHBondContact O-N 3.48Å; C413-L416 PolarHBondContact O-N 3.16Å; C413-L417 WeakPolarHBondContact O-CB 3.15Å; C413-L417 VanDerWaalsContact O-CG 3.25Å; C413-L417 WeakPolarHBondContact O-CG 3.46Å; C413-L417 PolarHBondContact O-N 3.46Å; C413-L435 HydrophobicContact CB-CD2 4.26Å
414D87.7Confident83.4Confident14 Ų1432.2 Ų32.28%0.07516%0.157CC..Hα-helixtrans-61.2-39.9176-176.467.3000112.4A410 N411 Y412 L416 L417 R418 H458 R462A410-D414 PolarHBondContact O-N 3.27Å; N411-D414 WeakPolarHBondContact O-CB 3.41Å; N411-D414 PolarHBondContact O-N 3.39Å; Y412-D414 VanDerWaalsContact C-N 3.31Å; Y412-D414 PolarHBondContact O-N 2.91Å; D414-L416 VanDerWaalsContact C-N 3.33Å; D414-L416 PolarHBondContact O-N 3.21Å; D414-L417 PolarHBondContact O-N 3.42Å; D414-R418 WeakPolarHBondContact O-CB 3.41Å; D414-R418 PolarHBondContact O-N 3.16Å; D414-R418 IonicContact OD2-NH1 3.22Å; D414-R418 PolarHBondContact OD2-NH1 3.04Å; D414-H458 HydrophobicContact CB-CB 4.02Å; D414-H458 IonicContact OD1-CG 3.3Å; D414-R462 WeakPolarHBondContact OD1-CD 3.33Å; D414-R462 IonicContact OD1-CZ 3.52Å; D414-R462 IonicContact OD1-NE 3.4Å; D414-R462 IonicContact OD1-NH1 2.76Å; D414-R462 PolarHBondContact OD1-NH1 3.1Å
415M85.2Confident83.8Confident46 Ų4638.5 Ų38.523%0.22718%0.184CC..Hα-helixtrans-63.4-38177.8-73.7179.356.800113S337 E338 N411 Y412 C413 T420 L422S337-M415 PolarHBondContact OG-SD 3.14Å; S337-M415 VanDerWaalsContact OG-SD 3.34Å; E338-M415 HydrophobicContact CB-CE 4.33Å; N411-M415 WeakPolarHBondContact O-CG 3.27Å; N411-M415 PolarHBondContact O-N 2.92Å; Y412-M415 WeakPolarHBondContact O-CB 3.31Å; Y412-M415 PolarHBondContact O-N 3.37Å; Y412-M415 VanDerWaalsContact O-N 3.14Å; C413-M415 VanDerWaalsContact C-N 3.32Å; C413-M415 PolarHBondContact O-N 3.48Å; M415-T420 VanDerWaalsContact O-CG2 3.31Å; M415-T420 WeakPolarHBondContact O-CG2 3.45Å; M415-T420 PolarHBondContact O-OG1 2.99Å; M415-L422 HydrophobicContact CE-CD2 4.24Å
416L87.1Confident84Confident0 Ų040.4 Ų40.40%020%0.195CC..Hα-helixtrans-72.6-41.8176.4-67.7177.4000112Y412 C413 D414 L422 S423 L426 I431 K434 L435Y412-L416 HydrophobicContact CD1-CD1 4.13Å; Y412-L416 HydrophobicContact CE1-CD1 3.68Å; Y412-L416 HydrophobicContact CE1-CG 4.39Å; Y412-L416 HydrophobicContact CE2-CD2 4.48Å; Y412-L416 HydrophobicContact CE2-CG 4.38Å; Y412-L416 PolarHBondContact O-N 2.62Å; Y412-L416 VanDerWaalsContact O-N 3.1Å; C413-L416 PolarHBondContact O-N 3.16Å; D414-L416 VanDerWaalsContact C-N 3.33Å; D414-L416 PolarHBondContact O-N 3.21Å; L416-L422 HydrophobicContact CD2-CD2 4.07Å; L416-S423 WeakPolarHBondContact O-CB 3.28Å; L416-L426 HydrophobicContact CD2-CD1 3.95Å; L416-I431 HydrophobicContact CB-CG2 4.32Å; L416-K434 HydrophobicContact CD1-CB 4.01Å; L416-K434 HydrophobicContact CD2-CD 4.46Å; L416-L435 HydrophobicContact CB-CD2 4.47Å; L416-L435 HydrophobicContact CD1-CD2 4.02Å; L416-L435 HydrophobicContact CD1-CG 4.26Å
417L88.6Confident84.2Confident3 Ų343.8 Ų43.82%0.01622%0.215CC..Hα-helixtrans-80.9-16.5-175.8-67.2169.2000113.7C413 D414 L435 S468 A469 I473 E474 M477C413-L417 WeakPolarHBondContact O-CB 3.15Å; C413-L417 VanDerWaalsContact O-CG 3.25Å; C413-L417 WeakPolarHBondContact O-CG 3.46Å; C413-L417 PolarHBondContact O-N 3.46Å; D414-L417 PolarHBondContact O-N 3.42Å; L417-L435 HydrophobicContact CD2-CD1 3.77Å; L417-L435 HydrophobicContact CG-CD1 4.37Å; L417-L435 HydrophobicContact CG-CD2 4.5Å; L417-S468 CarbonylContact O-C 3.51Å; L417-S468 WeakPolarHBondContact O-CA 3.43Å; L417-A469 WeakPolarHBondContact O-CB 3.19Å; L417-A469 PolarHBondContact O-N 3.02Å; L417-I473 HydrophobicContact CD2-CB 4.49Å; L417-I473 HydrophobicContact CD2-CG2 3.66Å; L417-E474 HydrophobicContact CD2-CG 4.32Å; L417-M477 HydrophobicContact CD1-CG 4.39Å
418R85.8Confident84.3Confident66 Ų6646.4 Ų46.425%0.24924%0.235CC..BIsolated β-bridgetrans-93.6154.1175.4-172.6177.479.8-155.28.2111.1D414 T420 S423 I467D414-R418 WeakPolarHBondContact O-CB 3.41Å; D414-R418 PolarHBondContact O-N 3.16Å; D414-R418 IonicContact OD2-NH1 3.22Å; D414-R418 PolarHBondContact OD2-NH1 3.04Å; R418-T420 HydrophobicContact CB-CG2 4.02Å; R418-T420 HydrophobicContact CG-CG2 4.29Å; R418-T420 PolarHBondContact O-N 3.34Å; R418-S423 WeakPolarHBondContact O-CB 3.48Å; R418-S423 PolarHBondContact O-OG 3.19Å; R418-I467 HydrophobicContact CG-CB 4.34Å; R418-I467 HydrophobicContact CG-CD1 4.2Å; R418-I467 HydrophobicContact CG-CG1 4.29Å
419K79.4Confident84.6Confident127 Ų12753.1 Ų53.155%0.55227%0.265SS*.SBendtrans-65.165.4170.2-64.1178.7-178.1160.20113.5I467 S468 A469K419-I467 PolarHBondContact N-O 2.94Å; K419-S468 WeakPolarHBondContact CE-O 3.22Å; K419-A469 HydrophobicContact CG-CB 4.33Å
420T78.3Confident84.6Confident9 Ų957.2 Ų57.26%0.05529%0.285CS..  trans-90.5165.8177.866.40000111.4M415 R418 L422 S423 K424M415-T420 VanDerWaalsContact O-CG2 3.31Å; M415-T420 WeakPolarHBondContact O-CG2 3.45Å; M415-T420 PolarHBondContact O-OG1 2.99Å; R418-T420 HydrophobicContact CB-CG2 4.02Å; R418-T420 HydrophobicContact CG-CG2 4.29Å; R418-T420 PolarHBondContact O-N 3.34Å; T420-L422 PolarHBondContact O-N 3.21Å; T420-L422 PolarHBondContact OG1-N 3.29Å; T420-S423 PolarHBondContact N-OG 3.41Å; T420-S423 PolarHBondContact O-OG 3.43Å; T420-S423 PolarHBondContact OG1-N 3.36Å; T420-S423 VanDerWaalsContact OG1-N 3.17Å; T420-S423 PolarHBondContact OG1-OG 3Å; T420-K424 WeakPolarHBondContact O-CB 3.48Å; T420-K424 VanDerWaalsContact O-CG 3.29Å; T420-K424 WeakPolarHBondContact O-CG 3.31Å; T420-K424 PolarHBondContact O-N 3.45Å; T420-K424 VanDerWaalsContact O-N 3.15Å
421P76.8Confident84.6Confident108 Ų10857.8 Ų57.870%0.70129%0.287SS*.THydrogen-bonded Turntrans-58.3-25.5169.9-24.435.2000113.6K425P421-K425 WeakPolarHBondContact O-CG 3.31Å
422L74.8Confident84.8Confident23 Ų2358.6 Ų58.612%0.1229%0.29CS..THydrogen-bonded Turntrans-75.2-53.7178.4179.565.5000111.3E338 Y412 M415 L416 T420 K424 K425 L426E338-L422 HydrophobicContact CG-CD2 4.26Å; E338-L422 WeakPolarHBondContact OE1-CD1 3.32Å; E338-L422 WeakPolarHBondContact OE2-CD2 3.39Å; Y412-L422 HydrophobicContact CE2-CD2 4.4Å; M415-L422 HydrophobicContact CE-CD2 4.24Å; L416-L422 HydrophobicContact CD2-CD2 4.07Å; T420-L422 PolarHBondContact O-N 3.21Å; T420-L422 PolarHBondContact OG1-N 3.29Å; L422-K424 PolarHBondContact O-N 3.38Å; L422-K425 WeakPolarHBondContact O-CB 3.5Å; L422-K425 PolarHBondContact O-N 3.24Å; L422-L426 HydrophobicContact CD1-CD1 4.46Å; L422-L426 HydrophobicContact CG-CD1 4.34Å
423S77.8Confident84.9Confident10 Ų1063.9 Ų63.97%0.0732%0.318CS..G310 helixtrans-63.6-28.1179.455.20000112.7L416 R418 T420 K425 L426L416-S423 WeakPolarHBondContact O-CB 3.28Å; R418-S423 WeakPolarHBondContact O-CB 3.48Å; R418-S423 PolarHBondContact O-OG 3.19Å; T420-S423 PolarHBondContact N-OG 3.41Å; T420-S423 PolarHBondContact O-OG 3.43Å; T420-S423 PolarHBondContact OG1-N 3.36Å; T420-S423 VanDerWaalsContact OG1-N 3.17Å; T420-S423 PolarHBondContact OG1-OG 3Å; S423-K425 PolarHBondContact O-N 3.24Å; S423-L426 PolarHBondContact O-N 2.94Å; S423-L426 VanDerWaalsContact O-O 3.14Å
424K80.7Confident84.8Confident166 Ų16665.9 Ų65.972%0.72233%0.326SS*.G310 helixtrans-67.8-18.2172.1-74-178.5-177.1-168.60114.6T420 L422T420-K424 WeakPolarHBondContact O-CB 3.48Å; T420-K424 VanDerWaalsContact O-CG 3.29Å; T420-K424 WeakPolarHBondContact O-CG 3.31Å; T420-K424 PolarHBondContact O-N 3.45Å; T420-K424 VanDerWaalsContact O-N 3.15Å; L422-K424 PolarHBondContact O-N 3.38Å
425K84.4Confident84.9Confident175 Ų17565.2 Ų65.276%0.76132%0.323SS*.G310 helixtrans-90.6-16.7177.4-72.1176.5-178.8-175.70112.9P421 L422 S423P421-K425 WeakPolarHBondContact O-CG 3.31Å; L422-K425 WeakPolarHBondContact O-CB 3.5Å; L422-K425 PolarHBondContact O-N 3.24Å; S423-K425 PolarHBondContact O-N 3.24Å
426L84.9Confident85.2Confident41 Ų4167.4 Ų67.422%0.21533%0.331CS..SBendtrans-104.6152.6-174.8-62.6170.4000110L416 L422 S423 E430 I431 K434L416-L426 HydrophobicContact CD2-CD1 3.95Å; L422-L426 HydrophobicContact CD1-CD1 4.46Å; L422-L426 HydrophobicContact CG-CD1 4.34Å; S423-L426 PolarHBondContact O-N 2.94Å; S423-L426 VanDerWaalsContact O-O 3.14Å; L426-E430 VanDerWaalsContact CA-OE2 3.3Å; L426-E430 WeakPolarHBondContact CA-OE2 3.4Å; L426-E430 HydrophobicContact CB-CB 4.32Å; L426-E430 HydrophobicContact CD2-CB 4.38Å; L426-E430 WeakPolarHBondContact CD2-OE2 3.47Å; L426-I431 HydrophobicContact CB-CD1 4.32Å; L426-I431 HydrophobicContact CB-CG1 3.88Å; L426-I431 HydrophobicContact CD1-CG1 4.3Å; L426-K434 HydrophobicContact CD1-CD 4.19Å
427T88.5Confident85.2Confident74 Ų7470.7 Ų70.745%0.45435%0.346SS..  trans-80161.9169.568.20000111E429 E430 I431T427-E429 PolarHBondContact O-N 3.44Å; T427-E430 PolarHBondContact N-OE2 2.71Å; T427-E430 PolarHBondContact O-N 2.97Å; T427-E430 VanDerWaalsContact OG1-CG 3.3Å; T427-E430 WeakPolarHBondContact OG1-CG 3.47Å; T427-E430 PolarHBondContact OG1-N 3.16Å; T427-I431 WeakPolarHBondContact O-CG1 3.41Å; T427-I431 PolarHBondContact O-N 2.92Å
428S87Confident85.2Confident64 Ų6470.5 Ų70.545%0.44835%0.346SS..Hα-helixtrans-56.9-38.3174.7-65.20000112.1I431 E432 D470S428-I431 PolarHBondContact O-N 3.48Å; S428-E432 PolarHBondContact O-N 3.03Å; S428-D470 PolarHBondContact OG-OD2 2.91Å
429E89.1Confident85.3Confident152 Ų15267.8 Ų67.871%0.7134%0.336SS*.Hα-helixtrans-66.2-42177-64.9178.9-177.500112.4T427 I431 E432 L433T427-E429 PolarHBondContact O-N 3.44Å; E429-I431 VanDerWaalsContact C-N 3.33Å; E429-I431 PolarHBondContact O-N 2.75Å; E429-E432 PolarHBondContact O-N 3.41Å; E429-L433 WeakPolarHBondContact O-CG 3.4Å; E429-L433 PolarHBondContact O-N 3.16Å
430E88.8Confident85.5Confident87 Ų8764.2 Ų64.241%0.40732%0.322SS..Hα-helixtrans-65.2-37.9176.3-73.3172.1161.400111.9L426 T427 L433 K434L426-E430 VanDerWaalsContact CA-OE2 3.3Å; L426-E430 WeakPolarHBondContact CA-OE2 3.4Å; L426-E430 HydrophobicContact CB-CB 4.32Å; L426-E430 HydrophobicContact CD2-CB 4.38Å; L426-E430 WeakPolarHBondContact CD2-OE2 3.47Å; T427-E430 PolarHBondContact N-OE2 2.71Å; T427-E430 PolarHBondContact O-N 2.97Å; T427-E430 VanDerWaalsContact OG1-CG 3.3Å; T427-E430 WeakPolarHBondContact OG1-CG 3.47Å; T427-E430 PolarHBondContact OG1-N 3.16Å; E430-L433 PolarHBondContact O-N 2.98Å; E430-K434 WeakPolarHBondContact O-CG 3.3Å; E430-K434 PolarHBondContact O-N 2.97Å
431I88.4Confident85.9Confident11 Ų1163.8 Ų63.86%0.05632%0.32CS..Hα-helixtrans-63.1-46.1174.7-69.6169.4000110L416 L426 T427 S428 E429 L433 K434 L435 I473L416-I431 HydrophobicContact CB-CG2 4.32Å; L426-I431 HydrophobicContact CB-CD1 4.32Å; L426-I431 HydrophobicContact CB-CG1 3.88Å; L426-I431 HydrophobicContact CD1-CG1 4.3Å; T427-I431 WeakPolarHBondContact O-CG1 3.41Å; T427-I431 PolarHBondContact O-N 2.92Å; S428-I431 PolarHBondContact O-N 3.48Å; E429-I431 VanDerWaalsContact C-N 3.33Å; E429-I431 PolarHBondContact O-N 2.75Å; I431-L433 PolarHBondContact O-N 3.33Å; I431-K434 PolarHBondContact O-N 3.44Å; I431-L435 HydrophobicContact CG2-CD1 3.84Å; I431-L435 HydrophobicContact CG2-CG 4.36Å; I431-L435 WeakPolarHBondContact O-CB 3.3Å; I431-L435 VanDerWaalsContact O-CG 3.26Å; I431-L435 WeakPolarHBondContact O-CG 3.41Å; I431-L435 PolarHBondContact O-N 3.36Å; I431-I473 HydrophobicContact CG2-CD1 4.23Å; I431-I473 HydrophobicContact CG2-CG2 4.47Å
432E90.5Very high86.4Confident55 Ų5558.7 Ų58.726%0.25729%0.287SS..Hα-helixtrans-58.7-46.2176168.6169.1-175.900112.1S428 E429 L435 K436 W480S428-E432 PolarHBondContact O-N 3.03Å; E429-E432 PolarHBondContact O-N 3.41Å; E432-L435 PolarHBondContact O-N 3.28Å; E432-K436 HydrophobicContact CG-CD 4.28Å; E432-K436 WeakPolarHBondContact O-CG 3.44Å; E432-K436 PolarHBondContact O-N 3.06Å; E432-K436 WeakPolarHBondContact OE1-CE 3.47Å; E432-K436 IonicContact OE1-NZ 3.46Å; E432-K436 PolarHBondContact OE1-NZ 3.35Å; E432-W480 HydrophobicContact CB-CH2 4.06Å; E432-W480 HydrophobicContact CG-CH2 3.54Å; E432-W480 HydrophobicContact CG-CZ2 3.79Å
433L89.3Confident86.9Confident111 Ų11163 Ų6358%0.58131%0.305SS*.Hα-helixtrans-60.2-48.3177.3-72174.2000111.7E429 E430 I431 L435 K436 E437E429-L433 WeakPolarHBondContact O-CG 3.4Å; E429-L433 PolarHBondContact O-N 3.16Å; E430-L433 PolarHBondContact O-N 2.98Å; I431-L433 PolarHBondContact O-N 3.33Å; L433-L435 VanDerWaalsContact C-N 3.31Å; L433-L435 PolarHBondContact O-N 3.15Å; L433-K436 PolarHBondContact O-N 3.35Å; L433-E437 WeakPolarHBondContact O-CG 3.16Å; L433-E437 PolarHBondContact O-N 2.83Å
434K87.8Confident87.3Confident41 Ų4164.3 Ų64.318%0.17831%0.308CS..Hα-helixtrans-61.4-37.6177.2-76.4-171.8166.4-153.30112.1E342 L416 L426 E430 I431 E437 V438E342-K434 IonicContact OE1-NZ 2.74Å; E342-K434 PolarHBondContact OE1-NZ 2.9Å; L416-K434 HydrophobicContact CD1-CB 4.01Å; L416-K434 HydrophobicContact CD2-CD 4.46Å; L426-K434 HydrophobicContact CD1-CD 4.19Å; E430-K434 WeakPolarHBondContact O-CG 3.3Å; E430-K434 PolarHBondContact O-N 2.97Å; I431-K434 PolarHBondContact O-N 3.44Å; K434-E437 PolarHBondContact O-N 3.36Å; K434-V438 VanDerWaalsContact O-CG2 3.31Å; K434-V438 WeakPolarHBondContact O-CG2 3.45Å; K434-V438 PolarHBondContact O-N 3.47Å
435L90.5Very high87.5Confident0 Ų056.7 Ų56.70%028%0.275CS..Hα-helixtrans-66.3-42.7175.5-72.2170.3000111.7C413 L416 L417 I431 E432 L433 E437 V438 L439 I473 M477 W480C413-L435 HydrophobicContact CB-CD2 4.26Å; L416-L435 HydrophobicContact CB-CD2 4.47Å; L416-L435 HydrophobicContact CD1-CD2 4.02Å; L416-L435 HydrophobicContact CD1-CG 4.26Å; L417-L435 HydrophobicContact CD2-CD1 3.77Å; L417-L435 HydrophobicContact CG-CD1 4.37Å; L417-L435 HydrophobicContact CG-CD2 4.5Å; I431-L435 HydrophobicContact CG2-CD1 3.84Å; I431-L435 HydrophobicContact CG2-CG 4.36Å; I431-L435 WeakPolarHBondContact O-CB 3.3Å; I431-L435 VanDerWaalsContact O-CG 3.26Å; I431-L435 WeakPolarHBondContact O-CG 3.41Å; I431-L435 PolarHBondContact O-N 3.36Å; E432-L435 PolarHBondContact O-N 3.28Å; L433-L435 VanDerWaalsContact C-N 3.31Å; L433-L435 PolarHBondContact O-N 3.15Å; L435-E437 VanDerWaalsContact C-N 3.32Å; L435-E437 PolarHBondContact O-N 3.05Å; L435-V438 WeakPolarHBondContact O-CB 3.47Å; L435-V438 PolarHBondContact O-N 2.97Å; L435-L439 VanDerWaalsContact O-CG 3.31Å; L435-L439 WeakPolarHBondContact O-CG 3.43Å; L435-L439 PolarHBondContact O-N 2.89Å; L435-I473 HydrophobicContact CD1-CG2 3.57Å; L435-M477 HydrophobicContact CD2-SD 4.39Å; L435-W480 HydrophobicContact CB-CE3 4.48Å; L435-W480 HydrophobicContact CB-CZ3 3.95Å; L435-W480 HydrophobicContact CD1-CZ3 4.05Å
436K90Very high87.5Confident92 Ų9251.5 Ų51.540%0.425%0.254SS..Hα-helixtrans-61.8-38.9175.1-73.1177.9-176.9171.10112.3E432 L433 L439 L440E432-K436 HydrophobicContact CG-CD 4.28Å; E432-K436 WeakPolarHBondContact O-CG 3.44Å; E432-K436 PolarHBondContact O-N 3.06Å; E432-K436 WeakPolarHBondContact OE1-CE 3.47Å; E432-K436 IonicContact OE1-NZ 3.46Å; E432-K436 PolarHBondContact OE1-NZ 3.35Å; L433-K436 PolarHBondContact O-N 3.35Å; K436-L439 WeakPolarHBondContact O-CB 3.39Å; K436-L439 PolarHBondContact O-N 3.19Å; K436-L440 PolarHBondContact O-N 2.94Å
437E87.8Confident87.5Confident69 Ų6950.5 Ų50.532%0.32225%0.249SC..Hα-helixtrans-63-42.2173.2-74.1-174.9147.100112.1L345 L433 K434 L435 L439 L440 V441L345-E437 HydrophobicContact CD1-CB 3.88Å; L345-E437 HydrophobicContact CD2-CB 3.75Å; L345-E437 HydrophobicContact CG-CB 4.44Å; L433-E437 WeakPolarHBondContact O-CG 3.16Å; L433-E437 PolarHBondContact O-N 2.83Å; K434-E437 PolarHBondContact O-N 3.36Å; L435-E437 VanDerWaalsContact C-N 3.32Å; L435-E437 PolarHBondContact O-N 3.05Å; E437-L439 VanDerWaalsContact C-N 3.3Å; E437-L439 PolarHBondContact O-N 3Å; E437-L440 VanDerWaalsContact O-CB 3.31Å; E437-L440 WeakPolarHBondContact O-CB 3.42Å; E437-L440 PolarHBondContact O-N 3.26Å; E437-L440 VanDerWaalsContact O-N 3.16Å; E437-V441 PolarHBondContact O-N 3.4Å
438V88.4Confident87.5Confident0 Ų047.8 Ų47.80%023%0.231CC..Hα-helixtrans-60.8-41.2174170.60000111.5V341 L409 Y412 K434 L435 L440 V441 L442V341-V438 HydrophobicContact CG1-CG2 3.85Å; L409-V438 HydrophobicContact CB-CG1 4.37Å; L409-V438 HydrophobicContact CD2-CG1 4.03Å; Y412-V438 HydrophobicContact CD1-CG2 3.68Å; Y412-V438 HydrophobicContact CE1-CG2 3.8Å; K434-V438 VanDerWaalsContact O-CG2 3.31Å; K434-V438 WeakPolarHBondContact O-CG2 3.45Å; K434-V438 PolarHBondContact O-N 3.47Å; L435-V438 WeakPolarHBondContact O-CB 3.47Å; L435-V438 PolarHBondContact O-N 2.97Å; V438-L440 VanDerWaalsContact C-N 3.28Å; V438-L440 PolarHBondContact O-N 3.47Å; V438-V441 WeakPolarHBondContact O-CB 3.38Å; V438-V441 PolarHBondContact O-N 3.36Å; V438-V441 VanDerWaalsContact O-N 3.14Å; V438-L442 PolarHBondContact O-N 3.49Å
439L88.2Confident87.5Confident8 Ų845.3 Ų45.34%0.04221%0.212CC..Hα-helixtrans-66-30.2177.3-69.9179.2000112.8L435 K436 E437 L442 K443 M477 W480 L481 V484L435-L439 VanDerWaalsContact O-CG 3.31Å; L435-L439 WeakPolarHBondContact O-CG 3.43Å; L435-L439 PolarHBondContact O-N 2.89Å; K436-L439 WeakPolarHBondContact O-CB 3.39Å; K436-L439 PolarHBondContact O-N 3.19Å; E437-L439 VanDerWaalsContact C-N 3.3Å; E437-L439 PolarHBondContact O-N 3Å; L439-L442 HydrophobicContact CD2-CD2 3.96Å; L439-L442 PolarHBondContact O-N 3.23Å; L439-K443 PolarHBondContact O-N 3.43Å; L439-M477 HydrophobicContact CD1-SD 4.42Å; L439-M477 HydrophobicContact CD2-CE 3.92Å; L439-M477 HydrophobicContact CD2-SD 4.5Å; L439-W480 HydrophobicContact CD1-CB 3.27Å; L439-W480 HydrophobicContact CD1-CD2 4.35Å; L439-W480 HydrophobicContact CD1-CE3 4.11Å; L439-W480 HydrophobicContact CD1-CG 4.09Å; L439-L481 HydrophobicContact CD2-CD2 3.79Å; L439-L481 HydrophobicContact CD2-CG 4.47Å; L439-V484 HydrophobicContact CB-CG2 3.86Å; L439-V484 HydrophobicContact CD1-CG2 4.36Å; L439-V484 HydrophobicContact CD2-CG2 4.22Å; L439-V484 HydrophobicContact CG-CG2 4.37Å
440L84.8Confident87.5Confident52 Ų5238.1 Ų38.127%0.27218%0.179SC..Hα-helixtrans-62.7-44.8170-179.863.4000111F348 K436 E437 V438 L442 K443 Y444F348-L440 HydrophobicContact CD1-CD2 4.09Å; F348-L440 HydrophobicContact CE1-CD2 3.45Å; F348-L440 VanDerWaalsContact CE1-CD2 3.45Å; F348-L440 HydrophobicContact CE2-CD2 4.4Å; F348-L440 HydrophobicContact CZ-CD2 3.64Å; F348-L440 HydrophobicContact CZ-CG 4.44Å; K436-L440 PolarHBondContact O-N 2.94Å; E437-L440 VanDerWaalsContact O-CB 3.31Å; E437-L440 WeakPolarHBondContact O-CB 3.42Å; E437-L440 PolarHBondContact O-N 3.26Å; E437-L440 VanDerWaalsContact O-N 3.16Å; V438-L440 VanDerWaalsContact C-N 3.28Å; V438-L440 PolarHBondContact O-N 3.47Å; L440-L442 VanDerWaalsContact C-N 3.33Å; L440-L442 PolarHBondContact O-N 3.03Å; L440-K443 HydrophobicContact CD1-CD 4.48Å; L440-K443 WeakPolarHBondContact O-CB 3.41Å; L440-K443 PolarHBondContact O-N 3Å; L440-Y444 HydrophobicContact CD1-CE2 4.23Å; L440-Y444 HydrophobicContact CG-CE2 4.39Å; L440-Y444 VanDerWaalsContact O-CD2 3.27Å; L440-Y444 WeakPolarHBondContact O-CD2 3.26Å; L440-Y444 WeakPolarHBondContact O-CE2 3.49Å
441V85.5Confident87.6Confident1 Ų134 Ų341%0.00616%0.159CC..Hα-helixtrans-63.4-40.7175.3-1760000111L345 Y374 V378 L409 E437 V438 K443 Y444 V445L345-V441 HydrophobicContact CD2-CG2 3.67Å; Y374-V441 HydrophobicContact CE1-CG1 4.21Å; Y374-V441 HydrophobicContact CE1-CG2 4.13Å; V378-V441 HydrophobicContact CG1-CG1 4.22Å; V378-V441 HydrophobicContact CG2-CG1 3.88Å; L409-V441 HydrophobicContact CD1-CG1 4.1Å; L409-V441 HydrophobicContact CD2-CG1 4.33Å; E437-V441 PolarHBondContact O-N 3.4Å; V438-V441 WeakPolarHBondContact O-CB 3.38Å; V438-V441 PolarHBondContact O-N 3.36Å; V438-V441 VanDerWaalsContact O-N 3.14Å; V441-K443 PolarHBondContact O-N 2.71Å; V441-Y444 PolarHBondContact O-N 2.98Å; V441-V445 PolarHBondContact O-N 2.95Å
442L87.4Confident87.6Confident0 Ų033.5 Ų33.50%016%0.157CC..Hα-helixtrans-59.3-28.7179.5-17363.8000112.9V438 L439 L440 Y444 V445 K448 F451 L481 V484 M486V438-L442 PolarHBondContact O-N 3.49Å; L439-L442 HydrophobicContact CD2-CD2 3.96Å; L439-L442 PolarHBondContact O-N 3.23Å; L440-L442 VanDerWaalsContact C-N 3.33Å; L440-L442 PolarHBondContact O-N 3.03Å; L442-Y444 PolarHBondContact O-N 3.33Å; L442-V445 HydrophobicContact CD1-CB 4.29Å; L442-V445 HydrophobicContact CD1-CG2 4.35Å; L442-V445 PolarHBondContact O-N 2.84Å; L442-K448 VanDerWaalsContact O-CE 3.28Å; L442-K448 WeakPolarHBondContact O-CE 3.26Å; L442-F451 HydrophobicContact CD1-CB 3.94Å; L442-F451 HydrophobicContact CD1-CD1 3.99Å; L442-F451 HydrophobicContact CD1-CD2 4.03Å; L442-F451 HydrophobicContact CD1-CG 3.7Å; L442-F451 HydrophobicContact CD2-CD1 3.86Å; L442-F451 HydrophobicContact CD2-CE1 3.76Å; L442-F451 HydrophobicContact CD2-CG 4.36Å; L442-F451 HydrophobicContact CD2-CZ 4.14Å; L442-L481 HydrophobicContact CD2-CD2 3.89Å; L442-V484 HydrophobicContact CD2-CG1 4.36Å; L442-V484 HydrophobicContact CG-CG1 4.49Å; L442-M486 HydrophobicContact CD2-SD 4.13Å
443K85.8Confident87.5Confident114 Ų11433.3 Ų33.350%0.49615%0.154SC..Hα-helixtrans-59.4-32174.2-70.8176.7-179178.60112.6L439 L440 V441 V484L439-K443 PolarHBondContact O-N 3.43Å; L440-K443 HydrophobicContact CD1-CD 4.48Å; L440-K443 WeakPolarHBondContact O-CB 3.41Å; L440-K443 PolarHBondContact O-N 3Å; V441-K443 PolarHBondContact O-N 2.71Å; K443-V484 HydrophobicContact CG-CG1 3.88Å
444Y85.1Confident87.4Confident38 Ų3828.2 Ų28.215%0.14913%0.127CC..Hα-helixtrans-92.3-10.2-177.3-55.1-64.9000113.5D370 Y374 N379 L440 V441 L442D370-Y444 HydrophobicContact CB-CE1 3.75Å; D370-Y444 WeakPolarHBondContact CB-OH 3.37Å; D370-Y444 WeakPolarHBondContact O-CD1 3.41Å; D370-Y444 PolarHBondContact OD2-OH 2.79Å; Y374-Y444 AromaticContact CD1-CD2 3.66Å; Y374-Y444 HydrophobicContact CD1-CD2 3.66Å; Y374-Y444 HydrophobicContact CD1-CE2 4.17Å; Y374-Y444 HydrophobicContact CD1-CG 4.22Å; Y374-Y444 HydrophobicContact CE1-CD2 4.14Å; N379-Y444 PolarHBondContact ND2-O 3.34Å; L440-Y444 HydrophobicContact CD1-CE2 4.23Å; L440-Y444 HydrophobicContact CG-CE2 4.39Å; L440-Y444 VanDerWaalsContact O-CD2 3.27Å; L440-Y444 WeakPolarHBondContact O-CD2 3.26Å; L440-Y444 WeakPolarHBondContact O-CE2 3.49Å; V441-Y444 PolarHBondContact O-N 2.98Å; L442-Y444 PolarHBondContact O-N 3.33Å
445V85.7Confident87.5Confident5 Ų526.4 Ų26.43%0.0312%0.119CC..  trans-70.9133.3174.8173.20000110.7V378 P406 L409 V441 L442 K448V378-V445 HydrophobicContact CG1-CB 4.46Å; V378-V445 HydrophobicContact CG1-CG2 3.5Å; P406-V445 HydrophobicContact CB-CG1 4.16Å; P406-V445 HydrophobicContact CG-CG1 3.63Å; L409-V445 HydrophobicContact CD1-CG2 3.92Å; V441-V445 PolarHBondContact O-N 2.95Å; L442-V445 HydrophobicContact CD1-CB 4.29Å; L442-V445 HydrophobicContact CD1-CG2 4.35Å; L442-V445 PolarHBondContact O-N 2.84Å; V445-K448 HydrophobicContact CB-CG 4.47Å; V445-K448 HydrophobicContact CG1-CG 4.35Å; V445-K448 VanDerWaalsContact O-CE 3.31Å; V445-K448 WeakPolarHBondContact O-CE 3.46Å; V445-K448 WeakPolarHBondContact O-CG 3.44Å
446Q83.8Confident87.4Confident67 Ų6727.5 Ų27.531%0.31312%0.124SC..SBendtrans-79.6-47.2176.4-70.3178.112.700112.4N379 K448N379-Q446 HydrophobicContact CB-CG 4.44Å; N379-Q446 WeakPolarHBondContact OD1-CB 3.27Å; N379-Q446 PolarHBondContact OD1-N 3.36Å; Q446-K448 PolarHBondContact O-N 2.99Å
447N84.8Confident87.2Confident19 Ų1923.7 Ų23.710%0.10211%0.11CC..  trans-95.769.6-175.3-65.5-18.6000110.8E402 D449 V450 L748E402-N447 PolarHBondContact OE2-ND2 3.01Å; N447-D449 VanDerWaalsContact C-N 3.25Å; N447-D449 PolarHBondContact O-N 3.1Å; N447-V450 HydrophobicContact CB-CG2 4.15Å; N447-V450 PolarHBondContact O-N 3Å; N447-L748 PolarHBondContact OD1-N 3.24Å
448K88.9Confident87.2Confident18 Ų1820.7 Ų20.78%0.07810%0.096CC..Hα-helixtrans-70.7-23.3-177.8-61-179.6174.6-1750112.6L442 V445 Q446 V450 F451 M452 M486 M746L442-K448 VanDerWaalsContact O-CE 3.28Å; L442-K448 WeakPolarHBondContact O-CE 3.26Å; V445-K448 HydrophobicContact CB-CG 4.47Å; V445-K448 HydrophobicContact CG1-CG 4.35Å; V445-K448 VanDerWaalsContact O-CE 3.31Å; V445-K448 WeakPolarHBondContact O-CE 3.46Å; V445-K448 WeakPolarHBondContact O-CG 3.44Å; Q446-K448 PolarHBondContact O-N 2.99Å; K448-V450 VanDerWaalsContact C-N 3.29Å; K448-V450 PolarHBondContact O-N 3.39Å; K448-F451 WeakPolarHBondContact O-CB 3.37Å; K448-F451 PolarHBondContact O-N 2.99Å; K448-M452 WeakPolarHBondContact O-CG 3.48Å; K448-M452 PolarHBondContact O-N 2.59Å; K448-M486 HydrophobicContact CB-CE 3.59Å; K448-M486 HydrophobicContact CB-SD 4.11Å; K448-M486 HydrophobicContact CD-CE 4.31Å; K448-M486 HydrophobicContact CD-SD 3.77Å; K448-M486 HydrophobicContact CG-CE 4.48Å; K448-M486 HydrophobicContact CG-SD 4.39Å; K448-M746 PolarHBondContact N-O 3.24Å
449D87.8Confident87.2Confident11 Ų1120.7 Ų20.76%0.05910%0.096CC..Hα-helixtrans-60-3717567.7-30.8000113.1N447 M452 R453 R712 M746N447-D449 VanDerWaalsContact C-N 3.25Å; N447-D449 PolarHBondContact O-N 3.1Å; D449-M452 PolarHBondContact O-N 2.67Å; D449-R453 WeakPolarHBondContact O-CB 3.06Å; D449-R453 PolarHBondContact O-N 3.47Å; D449-R712 IonicContact OD1-CZ 3.9Å; D449-R712 IonicContact OD1-NE 2.78Å; D449-R712 IonicContact OD1-NH2 3.84Å; D449-R712 PolarHBondContact OD1-NH2 3.46Å; D449-R712 WeakPolarHBondContact OD2-CG 3.11Å; D449-R712 IonicContact OD2-CZ 2.75Å; D449-R712 IonicContact OD2-NE 3.04Å; D449-R712 PolarHBondContact OD2-NE 2.97Å; D449-R712 IonicContact OD2-NH2 2.88Å; D449-R712 PolarHBondContact OD2-NH2 3.46Å; D449-M746 PolarHBondContact N-O 3.46Å
450V88.6Confident87.2Confident1 Ų121.3 Ų21.31%0.00610%0.1CC..Hα-helixtrans-59.9-53.1172.8-179.90000109.9L386 P406 N447 K448 M452 R453 Y454 I708L386-V450 HydrophobicContact CD2-CG1 3.94Å; L386-V450 HydrophobicContact CD2-CG2 4.46Å; P406-V450 HydrophobicContact CB-CB 3.94Å; P406-V450 HydrophobicContact CB-CG1 4.04Å; P406-V450 HydrophobicContact CG-CB 4.48Å; N447-V450 HydrophobicContact CB-CG2 4.15Å; N447-V450 PolarHBondContact O-N 3Å; K448-V450 VanDerWaalsContact C-N 3.29Å; K448-V450 PolarHBondContact O-N 3.39Å; V450-M452 VanDerWaalsContact C-N 3.31Å; V450-M452 PolarHBondContact O-N 3.45Å; V450-R453 PolarHBondContact O-N 3.43Å; V450-Y454 HydrophobicContact CG1-CD2 3.88Å; V450-Y454 HydrophobicContact CG1-CE2 3.94Å; V450-Y454 WeakPolarHBondContact O-CD2 3.21Å; V450-Y454 PolarHBondContact O-N 3.45Å; V450-Y454 VanDerWaalsContact O-N 3.14Å; V450-I708 HydrophobicContact CB-CD1 4.42Å; V450-I708 HydrophobicContact CG1-CD1 4.3Å; V450-I708 HydrophobicContact CG2-CD1 4.31Å; V450-I708 HydrophobicContact CG2-CG2 4.34Å
451F90.5Very high87.2Confident0 Ų019.3 Ų19.30%09%0.089CC..Hα-helixtrans-54.5-47.7177.1173.9-87.1000111.1P406 L409 A410 L442 K448 R453 Y454 H455 M477 L481P406-F451 HydrophobicContact CB-CB 4.05Å; L409-F451 HydrophobicContact CB-CD2 3.98Å; L409-F451 HydrophobicContact CB-CE2 4.1Å; A410-F451 HydrophobicContact CB-CD2 3.76Å; A410-F451 HydrophobicContact CB-CE2 4Å; A410-F451 HydrophobicContact CB-CG 4.42Å; L442-F451 HydrophobicContact CD1-CB 3.94Å; L442-F451 HydrophobicContact CD1-CD1 3.99Å; L442-F451 HydrophobicContact CD1-CD2 4.03Å; L442-F451 HydrophobicContact CD1-CG 3.7Å; L442-F451 HydrophobicContact CD2-CD1 3.86Å; L442-F451 HydrophobicContact CD2-CE1 3.76Å; L442-F451 HydrophobicContact CD2-CG 4.36Å; L442-F451 HydrophobicContact CD2-CZ 4.14Å; K448-F451 WeakPolarHBondContact O-CB 3.37Å; K448-F451 PolarHBondContact O-N 2.99Å; F451-R453 VanDerWaalsContact C-N 3.35Å; F451-R453 PolarHBondContact O-N 3.44Å; F451-Y454 PolarHBondContact O-N 3.41Å; F451-H455 HydrophobicContact CD1-CB 4.36Å; F451-H455 HydrophobicContact CE1-CB 4.02Å; F451-H455 HydrophobicContact CZ-CB 4.31Å; F451-H455 WeakPolarHBondContact O-CB 3.49Å; F451-H455 PolarHBondContact O-N 2.98Å; F451-M477 HydrophobicContact CZ-CE 4.16Å; F451-L481 HydrophobicContact CE1-CD2 3.72Å; F451-L481 HydrophobicContact CZ-CD2 4.42Å
452M88.9Confident87.3Confident2 Ų219.3 Ų19.31%0.019%0.089CC..Hα-helixtrans-63.6-38.6-178.5-69.9-56.5-71.800113.2K448 D449 V450 K456 L481 M486 Y490 L494K448-M452 WeakPolarHBondContact O-CG 3.48Å; K448-M452 PolarHBondContact O-N 2.59Å; D449-M452 PolarHBondContact O-N 2.67Å; V450-M452 VanDerWaalsContact C-N 3.31Å; V450-M452 PolarHBondContact O-N 3.45Å; M452-K456 WeakPolarHBondContact O-CB 3.47Å; M452-K456 PolarHBondContact O-N 3.23Å; M452-L481 HydrophobicContact CE-CD1 4.47Å; M452-L481 HydrophobicContact SD-CD1 4.4Å; M452-L481 HydrophobicContact SD-CD2 4.35Å; M452-M486 HydrophobicContact CG-CE 3.13Å; M452-M486 HydrophobicContact SD-CE 3.44Å; M452-M486 WeakPolarHBondContact SD-CE 3.49Å; M452-M486 HydrophobicContact SD-CG 4.24Å; M452-Y490 HydrophobicContact CB-CD1 4.11Å; M452-Y490 HydrophobicContact CB-CE1 4.47Å; M452-Y490 HydrophobicContact CE-CG 4.49Å; M452-L494 HydrophobicContact CE-CD1 3.8Å
453R87.2Confident87.4Confident51 Ų5120.2 Ų20.219%0.1929%0.093CC..Hα-helixtrans-64.4-50.4179.1-171.677.4-175.8156.320.4110.9D449 V450 F451 K456 A457 S538 E704 I708D449-R453 WeakPolarHBondContact O-CB 3.06Å; D449-R453 PolarHBondContact O-N 3.47Å; V450-R453 PolarHBondContact O-N 3.43Å; F451-R453 VanDerWaalsContact C-N 3.35Å; F451-R453 PolarHBondContact O-N 3.44Å; R453-K456 PolarHBondContact O-N 3.49Å; R453-A457 PolarHBondContact O-N 3.14Å; R453-S538 PolarHBondContact NH2-OG 3.3Å; R453-S538 VanDerWaalsContact NH2-OG 3.14Å; R453-E704 WeakPolarHBondContact CG-OE2 3.45Å; R453-E704 IonicContact CZ-OE2 2.59Å; R453-E704 IonicContact NE-OE2 3.41Å; R453-E704 PolarHBondContact NE-OE2 3.2Å; R453-E704 IonicContact NH2-OE1 3.05Å; R453-E704 IonicContact NH2-OE2 2.99Å; R453-E704 PolarHBondContact NH2-OE2 3.2Å; R453-I708 HydrophobicContact CB-CD1 3.94Å; R453-I708 HydrophobicContact CB-CG1 3.81Å; R453-I708 HydrophobicContact CG-CD1 4.05Å; R453-I708 HydrophobicContact CG-CG1 3.74Å
454Y87.3Confident87.4Confident4 Ų416.3 Ų16.32%0.0168%0.078CC..Hα-helixtrans-64.8-44.6177.7-80.8-81.6000111.9E407 V450 F451 K456 A457 H458 R701 N705 I708E407-Y454 HydrophobicContact CB-CD2 4.32Å; E407-Y454 HydrophobicContact CB-CE2 4.31Å; E407-Y454 HydrophobicContact CG-CD1 4.1Å; E407-Y454 HydrophobicContact CG-CD2 4.1Å; E407-Y454 HydrophobicContact CG-CE1 3.93Å; E407-Y454 HydrophobicContact CG-CE2 3.96Å; E407-Y454 HydrophobicContact CG-CG 4.19Å; V450-Y454 HydrophobicContact CG1-CD2 3.88Å; V450-Y454 HydrophobicContact CG1-CE2 3.94Å; V450-Y454 WeakPolarHBondContact O-CD2 3.21Å; V450-Y454 PolarHBondContact O-N 3.45Å; V450-Y454 VanDerWaalsContact O-N 3.14Å; F451-Y454 PolarHBondContact O-N 3.41Å; Y454-K456 VanDerWaalsContact C-N 3.33Å; Y454-K456 PolarHBondContact O-N 3.33Å; Y454-A457 PolarHBondContact O-N 3.14Å; Y454-H458 PolarHBondContact O-CD2 2.92Å; Y454-H458 VanDerWaalsContact O-CD2 3.24Å; Y454-H458 VanDerWaalsContact O-CG 3.26Å; Y454-H458 PolarHBondContact O-N 3.13Å; Y454-R701 HydrophobicContact CE1-CG 4.12Å; Y454-R701 WeakPolarHBondContact OH-CG 3.29Å; Y454-N705 PolarHBondContact OH-OD1 3.26Å; Y454-I708 HydrophobicContact CE2-CD1 4.17Å
455H90.2Very high87.3Confident2 Ų215.7 Ų15.71%0.0098%0.077CC..Hα-helixtrans-60.5-42.7177.5-173.781.8000111.7A410 F451 H458 L459A410-H455 HydrophobicContact CB-CB 4.42Å; F451-H455 HydrophobicContact CD1-CB 4.36Å; F451-H455 HydrophobicContact CE1-CB 4.02Å; F451-H455 HydrophobicContact CZ-CB 4.31Å; F451-H455 WeakPolarHBondContact O-CB 3.49Å; F451-H455 PolarHBondContact O-N 2.98Å; H455-H458 PolarHBondContact O-N 2.77Å; H455-L459 WeakPolarHBondContact O-CB 3.48Å; H455-L459 PolarHBondContact O-N 3.21Å
456K89Confident87.2Confident23 Ų2321.2 Ų21.210%0.111%0.106CC..Hα-helixtrans-60.8-47.3174-179.6-179176.8-178.90111.7M452 R453 Y454 H458 L459 T460 L494 M497 A536M452-K456 WeakPolarHBondContact O-CB 3.47Å; M452-K456 PolarHBondContact O-N 3.23Å; R453-K456 PolarHBondContact O-N 3.49Å; Y454-K456 VanDerWaalsContact C-N 3.33Å; Y454-K456 PolarHBondContact O-N 3.33Å; K456-H458 VanDerWaalsContact C-N 3.27Å; K456-H458 PolarHBondContact O-N 3.37Å; K456-L459 PolarHBondContact O-N 3.48Å; K456-T460 WeakPolarHBondContact O-CB 3.28Å; K456-T460 PolarHBondContact O-N 3.49Å; K456-T460 PolarHBondContact O-OG1 3.25Å; K456-T460 VanDerWaalsContact O-OG1 3.14Å; K456-L494 HydrophobicContact CB-CD2 3.89Å; K456-L494 HydrophobicContact CG-CD2 3.86Å; K456-M497 HydrophobicContact CG-SD 4.32Å; K456-A536 WeakPolarHBondContact CE-O 3.29Å; K456-A536 PolarHBondContact NZ-O 3Å
457A85.8Confident87.2Confident12 Ų1220.3 Ų20.310%0.09910%0.103CC..Hα-helixtrans-60.4-40.217900000111.5R453 Y454 R461R453-A457 PolarHBondContact O-N 3.14Å; Y454-A457 PolarHBondContact O-N 3.14Å; A457-R461 WeakPolarHBondContact O-CG 3.49Å; A457-R461 PolarHBondContact O-N 3.01Å; A457-R461 PolarHBondContact O-NH1 3.44Å
458H87.1Confident87.2Confident6 Ų620.1 Ų20.13%0.02810%0.103CC..Hα-helixtrans-66.2-48.4175.1-67.1-33.5000112.2N411 D414 Y454 H455 K456 T460 R461 R462N411-H458 PolarHBondContact OD1-NE2 3.18Å; D414-H458 HydrophobicContact CB-CB 4.02Å; D414-H458 IonicContact OD1-CG 3.3Å; Y454-H458 PolarHBondContact O-CD2 2.92Å; Y454-H458 VanDerWaalsContact O-CD2 3.24Å; Y454-H458 VanDerWaalsContact O-CG 3.26Å; Y454-H458 PolarHBondContact O-N 3.13Å; H455-H458 PolarHBondContact O-N 2.77Å; K456-H458 VanDerWaalsContact C-N 3.27Å; K456-H458 PolarHBondContact O-N 3.37Å; H458-T460 VanDerWaalsContact C-N 3.31Å; H458-T460 PolarHBondContact O-N 3.2Å; H458-R461 PolarHBondContact ND1-NH1 3.14Å; H458-R461 PolarHBondContact O-N 3.39Å; H458-R461 VanDerWaalsContact O-N 3.1Å; H458-R462 VanDerWaalsContact CB-NH1 3.32Å; H458-R462 WeakPolarHBondContact O-CG 3.18Å; H458-R462 PolarHBondContact O-N 3Å
459L90.1Very high86.9Confident1 Ų121.4 Ų21.41%0.00512%0.117CC..Hα-helixtrans-57.6-43.5175.7-178.366.9000111.7H455 K456 R461 R462 L463 E474 L494 M497 F498H455-L459 WeakPolarHBondContact O-CB 3.48Å; H455-L459 PolarHBondContact O-N 3.21Å; K456-L459 PolarHBondContact O-N 3.48Å; L459-R461 VanDerWaalsContact C-N 3.29Å; L459-R461 PolarHBondContact O-N 2.97Å; L459-R462 PolarHBondContact O-N 3.38Å; L459-R462 VanDerWaalsContact O-N 3.14Å; L459-L463 HydrophobicContact CD1-CD1 3.97Å; L459-L463 HydrophobicContact CD1-CD2 4.35Å; L459-L463 HydrophobicContact CD1-CG 3.89Å; L459-L463 HydrophobicContact CD2-CD1 4.33Å; L459-L463 HydrophobicContact CG-CD1 3.86Å; L459-L463 HydrophobicContact CG-CG 4.15Å; L459-L463 WeakPolarHBondContact O-CG 3.4Å; L459-L463 PolarHBondContact O-N 3.07Å; L459-E474 WeakPolarHBondContact CD1-OE2 3.48Å; L459-L494 HydrophobicContact CD2-CB 4.12Å; L459-L494 HydrophobicContact CD2-CD2 3.76Å; L459-L494 HydrophobicContact CD2-CG 4.39Å; L459-M497 HydrophobicContact CB-CE 4.38Å; L459-M497 HydrophobicContact CD2-CE 4.01Å; L459-M497 HydrophobicContact CD2-SD 4.4Å; L459-M497 HydrophobicContact CG-CE 4.01Å; L459-F498 HydrophobicContact CD1-CE2 4.14Å; L459-F498 HydrophobicContact CD1-CZ 3.72Å; L459-F498 HydrophobicContact CD2-CE2 3.86Å; L459-F498 HydrophobicContact CD2-CZ 4.3Å
460T88.1Confident86.8Confident20 Ų2023.1 Ų23.112%0.12313%0.126CC..Hα-helixtrans-53.6-47175.6-72.60000111.3K456 H458 I464 M497 W537K456-T460 WeakPolarHBondContact O-CB 3.28Å; K456-T460 PolarHBondContact O-N 3.49Å; K456-T460 PolarHBondContact O-OG1 3.25Å; K456-T460 VanDerWaalsContact O-OG1 3.14Å; H458-T460 VanDerWaalsContact C-N 3.31Å; H458-T460 PolarHBondContact O-N 3.2Å; T460-I464 HydrophobicContact CG2-CD1 3.7Å; T460-I464 WeakPolarHBondContact O-CB 3.46Å; T460-I464 WeakPolarHBondContact O-CD1 3.28Å; T460-I464 VanDerWaalsContact O-CG1 3.26Å; T460-I464 WeakPolarHBondContact O-CG1 3.27Å; T460-I464 PolarHBondContact O-N 3.23Å; T460-M497 WeakPolarHBondContact OG1-CE 3.48Å; T460-W537 HydrophobicContact CG2-CE3 3.78Å; T460-W537 HydrophobicContact CG2-CZ3 4.1Å
461R84.1Confident86.7Confident11 Ų1127.3 Ų27.34%0.04216%0.155CC..Hα-helixtrans-67-43.7177.6-65.8177.7-167.397.56.1111.5A457 H458 L459 L463 I464 L465 M578 T696A457-R461 WeakPolarHBondContact O-CG 3.49Å; A457-R461 PolarHBondContact O-N 3.01Å; A457-R461 PolarHBondContact O-NH1 3.44Å; H458-R461 PolarHBondContact ND1-NH1 3.14Å; H458-R461 PolarHBondContact O-N 3.39Å; H458-R461 VanDerWaalsContact O-N 3.1Å; L459-R461 VanDerWaalsContact C-N 3.29Å; L459-R461 PolarHBondContact O-N 2.97Å; R461-L463 PolarHBondContact O-N 3.32Å; R461-I464 PolarHBondContact O-N 3.21Å; R461-L465 VanDerWaalsContact O-CB 3.27Å; R461-L465 WeakPolarHBondContact O-CB 3.5Å; R461-L465 WeakPolarHBondContact O-CG 3.26Å; R461-L465 PolarHBondContact O-N 2.83Å; R461-M578 HydrophobicContact CG-CE 4.19Å; R461-M578 HydrophobicContact CG-SD 4.47Å; R461-T696 VanDerWaalsContact CZ-CG2 3.48Å
462R87.8Confident86.7Confident1 Ų133.4 Ų33.40%0.00418%0.184CC..Hα-helixtrans-60.9-43.5-178.1-68.9-164.5-54.9-88.30.3112.4D414 H458 L459 D466 I467 E474D414-R462 WeakPolarHBondContact OD1-CD 3.33Å; D414-R462 IonicContact OD1-CZ 3.52Å; D414-R462 IonicContact OD1-NE 3.4Å; D414-R462 IonicContact OD1-NH1 2.76Å; D414-R462 PolarHBondContact OD1-NH1 3.1Å; H458-R462 VanDerWaalsContact CB-NH1 3.32Å; H458-R462 WeakPolarHBondContact O-CG 3.18Å; H458-R462 PolarHBondContact O-N 3Å; L459-R462 PolarHBondContact O-N 3.38Å; L459-R462 VanDerWaalsContact O-N 3.14Å; R462-D466 WeakPolarHBondContact O-CA 3.44Å; R462-D466 PolarHBondContact O-N 3.24Å; R462-I467 HydrophobicContact CB-CG1 4.23Å; R462-I467 HydrophobicContact CG-CD1 4.39Å; R462-I467 HydrophobicContact CG-CG1 4.1Å; R462-I467 PolarHBondContact O-N 2.8Å; R462-I467 VanDerWaalsContact O-N 3.13Å; R462-E474 WeakPolarHBondContact CD-OE1 3.5Å; R462-E474 IonicContact CZ-OE1 3.29Å; R462-E474 IonicContact CZ-OE2 2.87Å; R462-E474 IonicContact NE-OE1 2.98Å; R462-E474 PolarHBondContact NE-OE1 2.94Å; R462-E474 IonicContact NE-OE2 2.91Å; R462-E474 PolarHBondContact NE-OE2 3.31Å; R462-E474 IonicContact NH2-OE1 3.83Å; R462-E474 IonicContact NH2-OE2 3.98Å; R462-E474 PolarHBondContact NH2-OE2 2.97Å
463L88.8Confident86.7Confident18 Ų1833.8 Ų33.89%0.09419%0.186CC..Hα-helixtrans-73.3-39.3178-65.3179.7000113.5L459 R461 M497 F498 I501 K530 W537L459-L463 HydrophobicContact CD1-CD1 3.97Å; L459-L463 HydrophobicContact CD1-CD2 4.35Å; L459-L463 HydrophobicContact CD1-CG 3.89Å; L459-L463 HydrophobicContact CD2-CD1 4.33Å; L459-L463 HydrophobicContact CG-CD1 3.86Å; L459-L463 HydrophobicContact CG-CG 4.15Å; L459-L463 WeakPolarHBondContact O-CG 3.4Å; L459-L463 PolarHBondContact O-N 3.07Å; R461-L463 PolarHBondContact O-N 3.32Å; L463-M497 HydrophobicContact CD1-CB 3.98Å; L463-M497 HydrophobicContact CD1-CE 4.19Å; L463-F498 HydrophobicContact CD1-CD1 4.47Å; L463-F498 HydrophobicContact CD1-CE1 4.42Å; L463-F498 HydrophobicContact CD1-CZ 4.46Å; L463-F498 HydrophobicContact CD2-CD1 4.05Å; L463-F498 HydrophobicContact CD2-CE1 3.72Å; L463-F498 HydrophobicContact CD2-CZ 4.31Å; L463-I501 HydrophobicContact CB-CD1 4.16Å; L463-I501 HydrophobicContact CB-CG1 4.14Å; L463-I501 HydrophobicContact CD1-CG1 4.36Å; L463-K530 PolarHBondContact O-NZ 3.38Å; L463-W537 HydrophobicContact CB-CH2 3.58Å; L463-W537 HydrophobicContact CB-CZ3 4.08Å; L463-W537 HydrophobicContact CD1-CH2 3.64Å; L463-W537 HydrophobicContact CD1-CZ2 4.23Å; L463-W537 HydrophobicContact CD1-CZ3 4.43Å; L463-W537 HydrophobicContact CG-CH2 4.27Å
464I86.3Confident86.9Confident33 Ų3331.5 Ų31.517%0.16918%0.177CC..Hα-helixtrans-69.4-41.4178-67.5167000111T460 R461 K530 L532 W537 M578T460-I464 HydrophobicContact CG2-CD1 3.7Å; T460-I464 WeakPolarHBondContact O-CB 3.46Å; T460-I464 WeakPolarHBondContact O-CD1 3.28Å; T460-I464 VanDerWaalsContact O-CG1 3.26Å; T460-I464 WeakPolarHBondContact O-CG1 3.27Å; T460-I464 PolarHBondContact O-N 3.23Å; R461-I464 PolarHBondContact O-N 3.21Å; I464-K530 PolarHBondContact O-NZ 3.17Å; I464-L532 HydrophobicContact CD1-CD1 4.07Å; I464-L532 HydrophobicContact CG1-CD1 3.81Å; I464-W537 HydrophobicContact CD1-CE3 4.05Å; I464-W537 HydrophobicContact CD1-CZ3 3.98Å; I464-W537 HydrophobicContact CG1-CE3 4.23Å; I464-W537 HydrophobicContact CG1-CH2 4.43Å; I464-W537 HydrophobicContact CG1-CZ3 3.69Å; I464-M578 HydrophobicContact CD1-CB 4.45Å; I464-M578 HydrophobicContact CD1-CG 4.49Å; I464-M578 HydrophobicContact CG2-CB 3.94Å
465L82.8Confident87Confident25 Ų2534.9 Ų34.913%0.13119%0.193CC..Hα-helixtrans-89.4-6.7-176.5-57.7177.5000113.7R461 I467 Q694R461-L465 VanDerWaalsContact O-CB 3.27Å; R461-L465 WeakPolarHBondContact O-CB 3.5Å; R461-L465 WeakPolarHBondContact O-CG 3.26Å; R461-L465 PolarHBondContact O-N 2.83Å; L465-I467 VanDerWaalsContact C-N 3.33Å; L465-I467 HydrophobicContact CB-CD1 4.21Å; L465-I467 HydrophobicContact CB-CG1 4.18Å; L465-I467 HydrophobicContact CB-CG2 3.9Å; L465-I467 HydrophobicContact CD1-CD1 4.23Å; L465-I467 PolarHBondContact O-N 3.45Å; L465-Q694 HydrophobicContact CD1-CB 3.91Å
466D84.1Confident87.1Confident121 Ų12136.8 Ų36.865%0.64720%0.203SC*.THydrogen-bonded Turntrans54.746.7-177.8-16729.1000113.1R462R462-D466 WeakPolarHBondContact O-CA 3.44Å; R462-D466 PolarHBondContact O-N 3.24Å
467I84.1Confident87.2Confident47 Ų4735.7 Ų35.724%0.24120%0.198CC..  trans-107.55.7-175.959177000113.4R418 K419 R462 L465R418-I467 HydrophobicContact CG-CB 4.34Å; R418-I467 HydrophobicContact CG-CD1 4.2Å; R418-I467 HydrophobicContact CG-CG1 4.29Å; K419-I467 PolarHBondContact N-O 2.94Å; R462-I467 HydrophobicContact CB-CG1 4.23Å; R462-I467 HydrophobicContact CG-CD1 4.39Å; R462-I467 HydrophobicContact CG-CG1 4.1Å; R462-I467 PolarHBondContact O-N 2.8Å; R462-I467 VanDerWaalsContact O-N 3.13Å; L465-I467 VanDerWaalsContact C-N 3.33Å; L465-I467 HydrophobicContact CB-CD1 4.21Å; L465-I467 HydrophobicContact CB-CG1 4.18Å; L465-I467 HydrophobicContact CB-CG2 3.9Å; L465-I467 HydrophobicContact CD1-CD1 4.23Å; L465-I467 PolarHBondContact O-N 3.45Å
468S84.7Confident87.5Confident16 Ų1635.4 Ų35.411%0.11220%0.196CC..BIsolated β-bridgetrans-60.3140.8174.3-66.40000110.7L417 K419 E474L417-S468 CarbonylContact O-C 3.51Å; L417-S468 WeakPolarHBondContact O-CA 3.43Å; K419-S468 WeakPolarHBondContact CE-O 3.22Å; S468-E474 WeakPolarHBondContact CB-OE1 3.25Å; S468-E474 PolarHBondContact OG-OE1 3.15Å
469A82.4Confident87.7Confident44 Ų4440.3 Ų40.336%0.36422%0.219SC..SBendtrans-72.5-43.3177.900000111.3L417 K419L417-A469 WeakPolarHBondContact O-CB 3.19Å; L417-A469 PolarHBondContact O-N 3.02Å; K419-A469 HydrophobicContact CG-CB 4.33Å
470D86.1Confident87.8Confident48 Ų4841.4 Ų41.426%0.25722%0.223SC..  trans-147.4127.1-176-169.2-37.8000108.6S428 E472 I473 E474S428-D470 PolarHBondContact OG-OD2 2.91Å; D470-E472 WeakPolarHBondContact OD1-CB 3.46Å; D470-E472 PolarHBondContact OD1-N 2.62Å; D470-I473 HydrophobicContact CB-CB 4.21Å; D470-I473 HydrophobicContact CB-CD1 3.93Å; D470-I473 HydrophobicContact CB-CG1 4.02Å; D470-I473 PolarHBondContact OD1-N 3.27Å; D470-E474 WeakPolarHBondContact O-CG 3.34Å
471S86.4Confident88Confident88 Ų8840.4 Ų40.462%0.61522%0.217SC*.Hα-helixtrans-77.5-29-178.672.80000112.8E474 E475S471-E474 PolarHBondContact O-N 3.16Å; S471-E475 PolarHBondContact O-N 3.48Å; S471-E475 VanDerWaalsContact O-N 3.11Å
472E89.6Confident88.3Confident129 Ų12946.2 Ų46.260%0.60324%0.239SC*.Hα-helixtrans-70-43.6-178.6-173.1175.1-179.400110.2D470 E474 E475 N476D470-E472 WeakPolarHBondContact OD1-CB 3.46Å; D470-E472 PolarHBondContact OD1-N 2.62Å; E472-E474 PolarHBondContact O-N 3.12Å; E472-E475 PolarHBondContact O-N 3.23Å; E472-N476 WeakPolarHBondContact O-CB 3.31Å; E472-N476 VanDerWaalsContact O-CG 3.28Å; E472-N476 PolarHBondContact O-N 3.34Å; E472-N476 PolarHBondContact O-ND2 3.02Å
473I89.9Confident88.3Confident10 Ų1053.6 Ų53.65%0.05127%0.273CS..Hα-helixtrans-62.1-34.8174.6-59.6179.8000111.2L417 I431 L435 D470 N476 M477L417-I473 HydrophobicContact CD2-CB 4.49Å; L417-I473 HydrophobicContact CD2-CG2 3.66Å; I431-I473 HydrophobicContact CG2-CD1 4.23Å; I431-I473 HydrophobicContact CG2-CG2 4.47Å; L435-I473 HydrophobicContact CD1-CG2 3.57Å; D470-I473 HydrophobicContact CB-CB 4.21Å; D470-I473 HydrophobicContact CB-CD1 3.93Å; D470-I473 HydrophobicContact CB-CG1 4.02Å; D470-I473 PolarHBondContact OD1-N 3.27Å; I473-N476 PolarHBondContact O-N 3.03Å; I473-M477 WeakPolarHBondContact O-CB 3.38Å; I473-M477 PolarHBondContact O-N 3.32Å
474E90Very high88.2Confident3 Ų353.7 Ų53.71%0.01427%0.274CS..Hα-helixtrans-67.7-39.2177-69.9-95.7-146.700112.3L417 L459 R462 S468 D470 S471 E472 F498L417-E474 HydrophobicContact CD2-CG 4.32Å; L459-E474 WeakPolarHBondContact CD1-OE2 3.48Å; R462-E474 WeakPolarHBondContact CD-OE1 3.5Å; R462-E474 IonicContact CZ-OE1 3.29Å; R462-E474 IonicContact CZ-OE2 2.87Å; R462-E474 IonicContact NE-OE1 2.98Å; R462-E474 PolarHBondContact NE-OE1 2.94Å; R462-E474 IonicContact NE-OE2 2.91Å; R462-E474 PolarHBondContact NE-OE2 3.31Å; R462-E474 IonicContact NH2-OE1 3.83Å; R462-E474 IonicContact NH2-OE2 3.98Å; R462-E474 PolarHBondContact NH2-OE2 2.97Å; S468-E474 WeakPolarHBondContact CB-OE1 3.25Å; S468-E474 PolarHBondContact OG-OE1 3.15Å; D470-E474 WeakPolarHBondContact O-CG 3.34Å; S471-E474 PolarHBondContact O-N 3.16Å; E472-E474 PolarHBondContact O-N 3.12Å; E474-F498 HydrophobicContact CB-CE1 3.89Å; E474-F498 HydrophobicContact CB-CZ 3.83Å
475E90.4Very high88.1Confident75 Ų7554 Ų5435%0.3529%0.285SS..Hα-helixtrans-67.1-46.7172.7-69.6-169.9-176.600110.7S471 E472 M477 V478 E479 F498 K502S471-E475 PolarHBondContact O-N 3.48Å; S471-E475 VanDerWaalsContact O-N 3.11Å; E472-E475 PolarHBondContact O-N 3.23Å; E475-M477 VanDerWaalsContact C-N 3.28Å; E475-M477 PolarHBondContact O-N 3.02Å; E475-V478 WeakPolarHBondContact O-CB 3.31Å; E475-V478 PolarHBondContact O-N 3.22Å; E475-E479 PolarHBondContact O-N 2.98Å; E475-F498 HydrophobicContact CG-CD1 4Å; E475-F498 HydrophobicContact CG-CE1 4.1Å; E475-F498 HydrophobicContact CG-CG 4.45Å; E475-K502 WeakPolarHBondContact OE1-CE 3.48Å; E475-K502 IonicContact OE1-NZ 2.7Å; E475-K502 PolarHBondContact OE1-NZ 3.33Å; E475-K502 IonicContact OE2-NZ 3.53Å
476N91.7Very high88.2Confident41 Ų4153.3 Ų53.322%0.21928%0.282CS..Hα-helixtrans-59-36.7176.7-71.8-17.5000112.4E472 I473 V478 E479 W480E472-N476 WeakPolarHBondContact O-CB 3.31Å; E472-N476 VanDerWaalsContact O-CG 3.28Å; E472-N476 PolarHBondContact O-N 3.34Å; E472-N476 PolarHBondContact O-ND2 3.02Å; I473-N476 PolarHBondContact O-N 3.03Å; N476-V478 VanDerWaalsContact C-N 3.26Å; N476-V478 PolarHBondContact O-N 2.96Å; N476-E479 WeakPolarHBondContact O-CB 3.33Å; N476-E479 PolarHBondContact O-N 3.32Å; N476-W480 HydrophobicContact CB-CD2 4.43Å; N476-W480 HydrophobicContact CB-CH2 4.02Å; N476-W480 HydrophobicContact CB-CZ2 3.71Å; N476-W480 VanDerWaalsContact O-CG 3.24Å; N476-W480 PolarHBondContact O-N 3Å
477M92Very high88.2Confident0 Ų048.5 Ų48.50%026%0.257CS..Hα-helixtrans-59.2-37.2176.3-176.263.6-176.800112L417 L435 L439 F451 I473 E475 E479 W480 L481L417-M477 HydrophobicContact CD1-CG 4.39Å; L435-M477 HydrophobicContact CD2-SD 4.39Å; L439-M477 HydrophobicContact CD1-SD 4.42Å; L439-M477 HydrophobicContact CD2-CE 3.92Å; L439-M477 HydrophobicContact CD2-SD 4.5Å; F451-M477 HydrophobicContact CZ-CE 4.16Å; I473-M477 WeakPolarHBondContact O-CB 3.38Å; I473-M477 PolarHBondContact O-N 3.32Å; E475-M477 VanDerWaalsContact C-N 3.28Å; E475-M477 PolarHBondContact O-N 3.02Å; M477-E479 VanDerWaalsContact C-N 3.34Å; M477-W480 HydrophobicContact SD-CE3 4.13Å; M477-L481 HydrophobicContact CE-CD1 4.34Å; M477-L481 HydrophobicContact CE-CD2 4.22Å; M477-L481 HydrophobicContact CE-CG 4.21Å; M477-L481 HydrophobicContact CG-CD1 4.46Å; M477-L481 WeakPolarHBondContact O-CB 3.26Å; M477-L481 VanDerWaalsContact O-CG 3.24Å; M477-L481 WeakPolarHBondContact O-CG 3.46Å; M477-L481 PolarHBondContact O-N 3.49Å
478V91.7Very high88.3Confident7 Ų749.2 Ų49.24%0.04227%0.27CS..Hα-helixtrans-67.4-37.8176-179.40000111.1E475 N476 R482 V491 L494 A495 F498E475-V478 WeakPolarHBondContact O-CB 3.31Å; E475-V478 PolarHBondContact O-N 3.22Å; N476-V478 VanDerWaalsContact C-N 3.26Å; N476-V478 PolarHBondContact O-N 2.96Å; V478-R482 PolarHBondContact O-N 3.21Å; V478-V491 HydrophobicContact CG1-CG1 3.73Å; V478-L494 HydrophobicContact CG1-CB 4.25Å; V478-L494 HydrophobicContact CG2-CB 4.07Å; V478-A495 HydrophobicContact CG1-CB 4.2Å; V478-F498 HydrophobicContact CG2-CD2 4.32Å; V478-F498 HydrophobicContact CG2-CE2 3.61Å; V478-F498 HydrophobicContact CG2-CZ 4.41Å
479E90.9Very high88.3Confident109 Ų10950.7 Ų50.751%0.50928%0.277SS..Hα-helixtrans-66.7-47.4175.5-59.8-166.2157.500111.5E475 N476 M477 L481 R482 E483E475-E479 PolarHBondContact O-N 2.98Å; N476-E479 WeakPolarHBondContact O-CB 3.33Å; N476-E479 PolarHBondContact O-N 3.32Å; M477-E479 VanDerWaalsContact C-N 3.34Å; E479-L481 VanDerWaalsContact C-N 3.29Å; E479-L481 PolarHBondContact O-N 3.4Å; E479-R482 WeakPolarHBondContact O-CA 3.44Å; E479-R482 WeakPolarHBondContact O-CB 3.16Å; E479-R482 PolarHBondContact O-N 3.08Å; E479-E483 PolarHBondContact O-N 3.26Å; E479-E483 VanDerWaalsContact O-N 3.07Å
480W93Very high88.4Confident23 Ų2349.7 Ų49.79%0.08726%0.264CS..Hα-helixtrans-63.6-34.7178.2-55.6-31.2000112.4E432 L435 L439 N476 M477 R482 E483 V484E432-W480 HydrophobicContact CB-CH2 4.06Å; E432-W480 HydrophobicContact CG-CH2 3.54Å; E432-W480 HydrophobicContact CG-CZ2 3.79Å; L435-W480 HydrophobicContact CB-CE3 4.48Å; L435-W480 HydrophobicContact CB-CZ3 3.95Å; L435-W480 HydrophobicContact CD1-CZ3 4.05Å; L439-W480 HydrophobicContact CD1-CB 3.27Å; L439-W480 HydrophobicContact CD1-CD2 4.35Å; L439-W480 HydrophobicContact CD1-CE3 4.11Å; L439-W480 HydrophobicContact CD1-CG 4.09Å; N476-W480 HydrophobicContact CB-CD2 4.43Å; N476-W480 HydrophobicContact CB-CH2 4.02Å; N476-W480 HydrophobicContact CB-CZ2 3.71Å; N476-W480 VanDerWaalsContact O-CG 3.24Å; N476-W480 PolarHBondContact O-N 3Å; M477-W480 HydrophobicContact SD-CE3 4.13Å; W480-R482 PolarHBondContact O-N 2.96Å; W480-E483 PolarHBondContact O-N 3.47Å; W480-V484 VanDerWaalsContact O-CG2 3.27Å; W480-V484 WeakPolarHBondContact O-CG2 3.29Å; W480-V484 PolarHBondContact O-N 2.98Å
481L91.6Very high88.6Confident0 Ų047.5 Ų47.50%025%0.252CS..Hα-helixtrans-61.6-34.6171.7-74.4170.4000111.8L439 L442 F451 M452 M477 E479 M486 V491 L494L439-L481 HydrophobicContact CD2-CD2 3.79Å; L439-L481 HydrophobicContact CD2-CG 4.47Å; L442-L481 HydrophobicContact CD2-CD2 3.89Å; F451-L481 HydrophobicContact CE1-CD2 3.72Å; F451-L481 HydrophobicContact CZ-CD2 4.42Å; M452-L481 HydrophobicContact CE-CD1 4.47Å; M452-L481 HydrophobicContact SD-CD1 4.4Å; M452-L481 HydrophobicContact SD-CD2 4.35Å; M477-L481 HydrophobicContact CE-CD1 4.34Å; M477-L481 HydrophobicContact CE-CD2 4.22Å; M477-L481 HydrophobicContact CE-CG 4.21Å; M477-L481 HydrophobicContact CG-CD1 4.46Å; M477-L481 WeakPolarHBondContact O-CB 3.26Å; M477-L481 VanDerWaalsContact O-CG 3.24Å; M477-L481 WeakPolarHBondContact O-CG 3.46Å; M477-L481 PolarHBondContact O-N 3.49Å; E479-L481 VanDerWaalsContact C-N 3.29Å; E479-L481 PolarHBondContact O-N 3.4Å; L481-M486 HydrophobicContact CB-CG 4.19Å; L481-M486 HydrophobicContact CD2-CG 3.97Å; L481-M486 WeakPolarHBondContact O-CB 3.49Å; L481-M486 WeakPolarHBondContact O-CG 3.37Å; L481-M486 PolarHBondContact O-N 2.89Å; L481-V491 HydrophobicContact CB-CG2 4.4Å; L481-L494 HydrophobicContact CD1-CD1 4.08Å
482R90.3Very high88.8Confident133 Ų13347.4 Ų47.450%0.50225%0.245SC..Hα-helixtrans-64.4-46.1172.9-162.2179.7-66.5172.32.2111.2V478 E479 W480 V484 G485 V491V478-R482 PolarHBondContact O-N 3.21Å; E479-R482 WeakPolarHBondContact O-CA 3.44Å; E479-R482 WeakPolarHBondContact O-CB 3.16Å; E479-R482 PolarHBondContact O-N 3.08Å; W480-R482 PolarHBondContact O-N 2.96Å; R482-V484 VanDerWaalsContact C-N 3.32Å; R482-V484 PolarHBondContact O-N 2.71Å; R482-G485 PolarHBondContact O-N 2.89Å; R482-G485 VanDerWaalsContact O-N 3.08Å; R482-V491 HydrophobicContact CB-CG1 4.12Å; R482-V491 HydrophobicContact CG-CG1 4.49Å
483E88.6Confident88.8Confident155 Ų15544.7 Ų44.772%0.72423%0.231SC*.Hα-helixtrans-64.2-34-179.7-65.6-177163.300113.4E479 W480 G485E479-E483 PolarHBondContact O-N 3.26Å; E479-E483 VanDerWaalsContact O-N 3.07Å; W480-E483 PolarHBondContact O-N 3.47Å; E483-G485 PolarHBondContact O-N 2.65Å; E483-G485 VanDerWaalsContact O-N 3.15Å
484V85.4Confident88.9Confident20 Ų2044.3 Ų44.312%0.12123%0.229CC..THydrogen-bonded Turntrans-68.5-8.5175.9171.50000112.5L439 L442 K443 W480 R482L439-V484 HydrophobicContact CB-CG2 3.86Å; L439-V484 HydrophobicContact CD1-CG2 4.36Å; L439-V484 HydrophobicContact CD2-CG2 4.22Å; L439-V484 HydrophobicContact CG-CG2 4.37Å; L442-V484 HydrophobicContact CD2-CG1 4.36Å; L442-V484 HydrophobicContact CG-CG1 4.49Å; K443-V484 HydrophobicContact CG-CG1 3.88Å; W480-V484 VanDerWaalsContact O-CG2 3.27Å; W480-V484 WeakPolarHBondContact O-CG2 3.29Å; W480-V484 PolarHBondContact O-N 2.98Å; R482-V484 VanDerWaalsContact C-N 3.32Å; R482-V484 PolarHBondContact O-N 2.71Å
485G83.4Confident89Confident39 Ų3945.9 Ų45.940%0.40224%0.243SC..THydrogen-bonded Turntrans82.130.6-179.700000112.8R482 E483R482-G485 PolarHBondContact O-N 2.89Å; R482-G485 VanDerWaalsContact O-N 3.08Å; E483-G485 PolarHBondContact O-N 2.65Å; E483-G485 VanDerWaalsContact O-N 3.15Å
486M86.2Confident89.1Confident11 Ų1148.4 Ų48.45%0.05425%0.249CC..  trans-66.8149.1170.6-65.4-52.8-61.700110.8L442 K448 M452 L481 A488 V491L442-M486 HydrophobicContact CD2-SD 4.13Å; K448-M486 HydrophobicContact CB-CE 3.59Å; K448-M486 HydrophobicContact CB-SD 4.11Å; K448-M486 HydrophobicContact CD-CE 4.31Å; K448-M486 HydrophobicContact CD-SD 3.77Å; K448-M486 HydrophobicContact CG-CE 4.48Å; K448-M486 HydrophobicContact CG-SD 4.39Å; M452-M486 HydrophobicContact CG-CE 3.13Å; M452-M486 HydrophobicContact SD-CE 3.44Å; M452-M486 WeakPolarHBondContact SD-CE 3.49Å; M452-M486 HydrophobicContact SD-CG 4.24Å; L481-M486 HydrophobicContact CB-CG 4.19Å; L481-M486 HydrophobicContact CD2-CG 3.97Å; L481-M486 WeakPolarHBondContact O-CB 3.49Å; L481-M486 WeakPolarHBondContact O-CG 3.37Å; L481-M486 PolarHBondContact O-N 2.89Å; M486-A488 PolarHBondContact O-N 2.85Å; M486-V491 HydrophobicContact CB-CG2 3.92Å
487P83.9Confident89.2Confident20 Ų2046.4 Ų46.413%0.1324%0.239CC..  trans-57.1128.2-179.1-20.729.3000112.2D489 Y490 V491 M746P487-D489 WeakPolarHBondContact CB-OD1 3.42Å; P487-D489 PolarHBondContact O-N 3.01Å; P487-Y490 HydrophobicContact CB-CD2 4.01Å; P487-Y490 HydrophobicContact CG-CD2 4.38Å; P487-Y490 PolarHBondContact O-N 2.97Å; P487-Y490 VanDerWaalsContact O-N 3.1Å; P487-V491 PolarHBondContact O-N 3.21Å; P487-M746 HydrophobicContact CB-CG 4.46Å; P487-M746 HydrophobicContact CG-CG 3.61Å; P487-M746 HydrophobicContact CG-SD 4.42Å
488A86.1Confident89.2Confident63 Ų6347.5 Ų47.552%0.52124%0.243SC..Hα-helixtrans-60.8-31.7-172.800000113.1M486 Y490 V491 N492M486-A488 PolarHBondContact O-N 2.85Å; A488-Y490 VanDerWaalsContact C-N 3.28Å; A488-Y490 PolarHBondContact O-N 2.96Å; A488-V491 PolarHBondContact O-N 2.94Å; A488-N492 VanDerWaalsContact O-CB 3.22Å; A488-N492 WeakPolarHBondContact O-CB 3.37Å; A488-N492 PolarHBondContact O-N 2.96Å; A488-N492 PolarHBondContact O-ND2 2.91Å
489D84.6Confident89.2Confident47 Ų4752.8 Ų52.825%0.25127%0.268SS..Hα-helixtrans-63.4-32.2178.569.2-53.7000112.9P487 K493 R715P487-D489 WeakPolarHBondContact CB-OD1 3.42Å; P487-D489 PolarHBondContact O-N 3.01Å; D489-K493 WeakPolarHBondContact O-CD 3.41Å; D489-K493 VanDerWaalsContact O-CG 3.29Å; D489-K493 WeakPolarHBondContact O-CG 3.18Å; D489-R715 IonicContact OD2-CZ 3.78Å; D489-R715 IonicContact OD2-NH2 2.62Å; D489-R715 PolarHBondContact OD2-NH2 2.92Å
490Y84.2Confident89.3Confident23 Ų2348.8 Ų48.89%0.0925%0.249CC..Hα-helixtrans-78.1-47.6174.3-75.4-96000111.6M452 P487 A488 N492 K493 L494 L711M452-Y490 HydrophobicContact CB-CD1 4.11Å; M452-Y490 HydrophobicContact CB-CE1 4.47Å; M452-Y490 HydrophobicContact CE-CG 4.49Å; P487-Y490 HydrophobicContact CB-CD2 4.01Å; P487-Y490 HydrophobicContact CG-CD2 4.38Å; P487-Y490 PolarHBondContact O-N 2.97Å; P487-Y490 VanDerWaalsContact O-N 3.1Å; A488-Y490 VanDerWaalsContact C-N 3.28Å; A488-Y490 PolarHBondContact O-N 2.96Å; Y490-N492 VanDerWaalsContact C-N 3.27Å; Y490-N492 PolarHBondContact O-N 3.4Å; Y490-K493 WeakPolarHBondContact O-CB 3.43Å; Y490-K493 PolarHBondContact O-N 2.99Å; Y490-L494 PolarHBondContact O-N 3.24Å; Y490-L494 VanDerWaalsContact O-N 3.1Å; Y490-L711 HydrophobicContact CE1-CD2 4.45Å; Y490-L711 WeakPolarHBondContact OH-CD2 3.31Å
491V90.7Very high89.2Confident1 Ų148.6 Ų48.61%0.00625%0.25CC..Hα-helixtrans-59.2-41.6-180178.40000110.7V478 L481 R482 M486 P487 A488 K493 L494 A495V478-V491 HydrophobicContact CG1-CG1 3.73Å; L481-V491 HydrophobicContact CB-CG2 4.4Å; R482-V491 HydrophobicContact CB-CG1 4.12Å; R482-V491 HydrophobicContact CG-CG1 4.49Å; M486-V491 HydrophobicContact CB-CG2 3.92Å; P487-V491 PolarHBondContact O-N 3.21Å; A488-V491 PolarHBondContact O-N 2.94Å; V491-K493 VanDerWaalsContact C-N 3.29Å; V491-K493 PolarHBondContact O-N 3.39Å; V491-L494 PolarHBondContact O-N 2.78Å; V491-L494 VanDerWaalsContact O-N 3.16Å; V491-A495 PolarHBondContact O-N 3.06Å
492N90.9Very high89.2Confident86 Ų8653.6 Ų53.646%0.4627%0.272SS..Hα-helixtrans-64.5-32.2176.8-70-18000112.9A488 Y490 R496A488-N492 VanDerWaalsContact O-CB 3.22Å; A488-N492 WeakPolarHBondContact O-CB 3.37Å; A488-N492 PolarHBondContact O-N 2.96Å; A488-N492 PolarHBondContact O-ND2 2.91Å; Y490-N492 VanDerWaalsContact C-N 3.27Å; Y490-N492 PolarHBondContact O-N 3.4Å; N492-R496 WeakPolarHBondContact O-CB 3.27Å; N492-R496 PolarHBondContact O-N 3.4Å
493K90Very high89.3Confident72 Ų7250.6 Ų50.631%0.31327%0.268SS..Hα-helixtrans-68.1-41.3173.3-73.3166.9-174.6166.70111.1D489 Y490 V491 R496 M497D489-K493 WeakPolarHBondContact O-CD 3.41Å; D489-K493 VanDerWaalsContact O-CG 3.29Å; D489-K493 WeakPolarHBondContact O-CG 3.18Å; Y490-K493 WeakPolarHBondContact O-CB 3.43Å; Y490-K493 PolarHBondContact O-N 2.99Å; V491-K493 VanDerWaalsContact C-N 3.29Å; V491-K493 PolarHBondContact O-N 3.39Å; K493-R496 PolarHBondContact O-N 3.34Å; K493-M497 WeakPolarHBondContact O-CG 3.34Å; K493-M497 PolarHBondContact O-N 3.41Å; K493-M497 VanDerWaalsContact O-N 3.11Å
494L91.9Very high89.5Confident2 Ų243.3 Ų43.31%0.0123%0.234CC..Hα-helixtrans-63.8-47.5175.9-58.3-179.4000111M452 K456 L459 V478 L481 Y490 V491 R496 M497 F498M452-L494 HydrophobicContact CE-CD1 3.8Å; K456-L494 HydrophobicContact CB-CD2 3.89Å; K456-L494 HydrophobicContact CG-CD2 3.86Å; L459-L494 HydrophobicContact CD2-CB 4.12Å; L459-L494 HydrophobicContact CD2-CD2 3.76Å; L459-L494 HydrophobicContact CD2-CG 4.39Å; V478-L494 HydrophobicContact CG1-CB 4.25Å; V478-L494 HydrophobicContact CG2-CB 4.07Å; L481-L494 HydrophobicContact CD1-CD1 4.08Å; Y490-L494 PolarHBondContact O-N 3.24Å; Y490-L494 VanDerWaalsContact O-N 3.1Å; V491-L494 PolarHBondContact O-N 2.78Å; V491-L494 VanDerWaalsContact O-N 3.16Å; L494-R496 VanDerWaalsContact C-N 3.28Å; L494-R496 PolarHBondContact O-N 2.97Å; L494-M497 HydrophobicContact CD2-SD 4.04Å; L494-M497 VanDerWaalsContact O-CB 3.28Å; L494-M497 WeakPolarHBondContact O-CB 3.25Å; L494-M497 PolarHBondContact O-N 3.4Å; L494-F498 VanDerWaalsContact O-CD2 3.31Å; L494-F498 WeakPolarHBondContact O-CD2 3.45Å; L494-F498 PolarHBondContact O-N 3.3Å
495A92Very high89.7Confident37 Ų3747.2 Ų47.231%0.30625%0.251SS..Hα-helixtrans-57.8-41175.800000112.2V478 V491 M497 F498 Q499V478-A495 HydrophobicContact CG1-CB 4.2Å; V491-A495 PolarHBondContact O-N 3.06Å; A495-M497 VanDerWaalsContact C-N 3.27Å; A495-M497 PolarHBondContact O-N 3.32Å; A495-F498 PolarHBondContact O-N 2.9Å; A495-Q499 PolarHBondContact O-N 3.18Å
496R92.6Very high90.1Very high127 Ų12750 Ų5048%0.47926%0.257SS..Hα-helixtrans-63.2-31.3175-175.3166.8-70.1156.70.7112.9N492 K493 L494 Q499 D500 A536N492-R496 WeakPolarHBondContact O-CB 3.27Å; N492-R496 PolarHBondContact O-N 3.4Å; K493-R496 PolarHBondContact O-N 3.34Å; L494-R496 VanDerWaalsContact C-N 3.28Å; L494-R496 PolarHBondContact O-N 2.97Å; R496-Q499 PolarHBondContact O-N 2.7Å; R496-D500 VanDerWaalsContact O-CG 3.23Å; R496-D500 PolarHBondContact O-N 3.47Å; R496-A536 HydrophobicContact CB-CB 4.44Å; R496-A536 HydrophobicContact CG-CB 4.17Å
497M92.9Very high90.2Very high0 Ų050.7 Ų50.70%026%0.261CS..Hα-helixtrans-61.7-43.3175.4-67.5166.655.800111.4K456 L459 T460 L463 K493 L494 A495 Q499 D500 I501 A536 W537K456-M497 HydrophobicContact CG-SD 4.32Å; L459-M497 HydrophobicContact CB-CE 4.38Å; L459-M497 HydrophobicContact CD2-CE 4.01Å; L459-M497 HydrophobicContact CD2-SD 4.4Å; L459-M497 HydrophobicContact CG-CE 4.01Å; T460-M497 WeakPolarHBondContact OG1-CE 3.48Å; L463-M497 HydrophobicContact CD1-CB 3.98Å; L463-M497 HydrophobicContact CD1-CE 4.19Å; K493-M497 WeakPolarHBondContact O-CG 3.34Å; K493-M497 PolarHBondContact O-N 3.41Å; K493-M497 VanDerWaalsContact O-N 3.11Å; L494-M497 HydrophobicContact CD2-SD 4.04Å; L494-M497 VanDerWaalsContact O-CB 3.28Å; L494-M497 WeakPolarHBondContact O-CB 3.25Å; L494-M497 PolarHBondContact O-N 3.4Å; A495-M497 VanDerWaalsContact C-N 3.27Å; A495-M497 PolarHBondContact O-N 3.32Å; M497-Q499 VanDerWaalsContact C-N 3.34Å; M497-Q499 PolarHBondContact O-N 3.4Å; M497-D500 PolarHBondContact O-N 3.04Å; M497-I501 WeakPolarHBondContact O-CG1 3.22Å; M497-I501 PolarHBondContact O-N 3.34Å; M497-I501 VanDerWaalsContact O-N 3.09Å; M497-A536 HydrophobicContact CG-CB 4.45Å; M497-W537 HydrophobicContact CB-CD2 4.39Å; M497-W537 HydrophobicContact CB-CH2 4.06Å; M497-W537 HydrophobicContact CB-CZ2 3.46Å; M497-W537 VanDerWaalsContact CB-CZ2 3.46Å; M497-W537 HydrophobicContact CE-CD2 4.11Å; M497-W537 HydrophobicContact CE-CE3 3.78Å; M497-W537 HydrophobicContact CE-CH2 4Å; M497-W537 HydrophobicContact CE-CZ2 4.32Å; M497-W537 HydrophobicContact CE-CZ3 3.7Å; M497-W537 HydrophobicContact CG-CD2 3.89Å; M497-W537 HydrophobicContact CG-CE3 4.5Å; M497-W537 HydrophobicContact CG-CG 4.24Å; M497-W537 HydrophobicContact CG-CZ2 3.91Å; M497-W537 VanDerWaalsContact O-CZ2 3.28Å; M497-W537 WeakPolarHBondContact O-CZ2 3.15Å
498F92.1Very high90.5Very high23 Ų2350.1 Ų50.110%0.10126%0.256CS..Hα-helixtrans-63.1-40.8174.8-69.6-87.8000112.4L459 L463 E474 E475 V478 L494 A495 D500 I501 K502L459-F498 HydrophobicContact CD1-CE2 4.14Å; L459-F498 HydrophobicContact CD1-CZ 3.72Å; L459-F498 HydrophobicContact CD2-CE2 3.86Å; L459-F498 HydrophobicContact CD2-CZ 4.3Å; L463-F498 HydrophobicContact CD1-CD1 4.47Å; L463-F498 HydrophobicContact CD1-CE1 4.42Å; L463-F498 HydrophobicContact CD1-CZ 4.46Å; L463-F498 HydrophobicContact CD2-CD1 4.05Å; L463-F498 HydrophobicContact CD2-CE1 3.72Å; L463-F498 HydrophobicContact CD2-CZ 4.31Å; E474-F498 HydrophobicContact CB-CE1 3.89Å; E474-F498 HydrophobicContact CB-CZ 3.83Å; E475-F498 HydrophobicContact CG-CD1 4Å; E475-F498 HydrophobicContact CG-CE1 4.1Å; E475-F498 HydrophobicContact CG-CG 4.45Å; V478-F498 HydrophobicContact CG2-CD2 4.32Å; V478-F498 HydrophobicContact CG2-CE2 3.61Å; V478-F498 HydrophobicContact CG2-CZ 4.41Å; L494-F498 VanDerWaalsContact O-CD2 3.31Å; L494-F498 WeakPolarHBondContact O-CD2 3.45Å; L494-F498 PolarHBondContact O-N 3.3Å; A495-F498 PolarHBondContact O-N 2.9Å; F498-D500 PolarHBondContact O-N 3.03Å; F498-I501 PolarHBondContact O-N 2.9Å; F498-K502 PolarHBondContact O-N 3.48Å; F498-K502 VanDerWaalsContact O-N 3.15Å
499Q92.6Very high90.6Very high118 Ų11852.8 Ų52.855%0.55126%0.258SS*.Hα-helixtrans-61.9-43.4175.4-172.117719.200111.9A495 R496 M497 I501 K502 V503A495-Q499 PolarHBondContact O-N 3.18Å; R496-Q499 PolarHBondContact O-N 2.7Å; M497-Q499 VanDerWaalsContact C-N 3.34Å; M497-Q499 PolarHBondContact O-N 3.4Å; Q499-I501 VanDerWaalsContact C-N 3.29Å; Q499-I501 PolarHBondContact O-N 3.01Å; Q499-K502 PolarHBondContact O-N 3.45Å; Q499-V503 HydrophobicContact CG-CG2 4.46Å; Q499-V503 WeakPolarHBondContact O-CG2 3.37Å; Q499-V503 PolarHBondContact O-N 3.25Å
500D92.7Very high90.8Very high24 Ų2453.5 Ų53.513%0.12826%0.264CS..Hα-helixtrans-62-36.3177.9-70.1-18.1000111.6R496 M497 F498 S504 L532 N533 W537R496-D500 VanDerWaalsContact O-CG 3.23Å; R496-D500 PolarHBondContact O-N 3.47Å; M497-D500 PolarHBondContact O-N 3.04Å; F498-D500 PolarHBondContact O-N 3.03Å; D500-S504 VanDerWaalsContact O-CB 3.26Å; D500-S504 WeakPolarHBondContact O-CB 3.34Å; D500-S504 PolarHBondContact O-N 3.2Å; D500-L532 HydrophobicContact CB-CD2 4.16Å; D500-N533 VanDerWaalsContact OD2-CB 3.3Å; D500-N533 WeakPolarHBondContact OD2-CB 3.33Å; D500-N533 PolarHBondContact OD2-N 3.47Å; D500-W537 HydrophobicContact CB-CZ2 4.47Å; D500-W537 VanDerWaalsContact OD2-CD1 3.28Å; D500-W537 PolarHBondContact OD2-NE1 3.07Å
501I91.7Very high90.9Very high19 Ų1952.6 Ų52.610%0.09726%0.26CS..Hα-helixtrans-64.1-49.4175.1-67.4-69.4000110.9L463 M497 F498 Q499 V503 S504 E505 K530 L532 W537L463-I501 HydrophobicContact CB-CD1 4.16Å; L463-I501 HydrophobicContact CB-CG1 4.14Å; L463-I501 HydrophobicContact CD1-CG1 4.36Å; M497-I501 WeakPolarHBondContact O-CG1 3.22Å; M497-I501 PolarHBondContact O-N 3.34Å; M497-I501 VanDerWaalsContact O-N 3.09Å; F498-I501 PolarHBondContact O-N 2.9Å; Q499-I501 VanDerWaalsContact C-N 3.29Å; Q499-I501 PolarHBondContact O-N 3.01Å; I501-V503 PolarHBondContact O-N 3.43Å; I501-S504 WeakPolarHBondContact O-CB 3.4Å; I501-S504 PolarHBondContact O-N 3.28Å; I501-S504 VanDerWaalsContact O-N 3.09Å; I501-E505 WeakPolarHBondContact O-CG 3.3Å; I501-E505 PolarHBondContact O-N 2.99Å; I501-K530 HydrophobicContact CD1-CD 4.42Å; I501-L532 HydrophobicContact CD1-CD2 3.91Å; I501-W537 HydrophobicContact CD1-CH2 3.79Å; I501-W537 HydrophobicContact CD1-CZ2 4.02Å; I501-W537 HydrophobicContact CG1-CH2 3.88Å; I501-W537 HydrophobicContact CG1-CZ2 3.85Å
502K91.4Very high90.7Very high106 Ų10655.1 Ų55.146%0.46127%0.271SS..Hα-helixtrans-59-47.6178.7-67.7176.9-176.5174.50111.3E475 F498 Q499 S504 E505 D506E475-K502 WeakPolarHBondContact OE1-CE 3.48Å; E475-K502 IonicContact OE1-NZ 2.7Å; E475-K502 PolarHBondContact OE1-NZ 3.33Å; E475-K502 IonicContact OE2-NZ 3.53Å; F498-K502 PolarHBondContact O-N 3.48Å; F498-K502 VanDerWaalsContact O-N 3.15Å; Q499-K502 PolarHBondContact O-N 3.45Å; K502-S504 VanDerWaalsContact C-N 3.27Å; K502-S504 PolarHBondContact O-N 3.44Å; K502-E505 WeakPolarHBondContact O-CB 3.43Å; K502-E505 PolarHBondContact O-N 3.03Å; K502-E505 VanDerWaalsContact O-N 3.13Å; K502-D506 PolarHBondContact O-N 3.36Å; K502-D506 VanDerWaalsContact O-N 3.1Å
503V92.5Very high90.5Very high70 Ų7057.6 Ų57.642%0.42428%0.28SS..Hα-helixtrans-60.7-37.9175.8172.20000111.5Q499 I501 D506 L507Q499-V503 HydrophobicContact CG-CG2 4.46Å; Q499-V503 WeakPolarHBondContact O-CG2 3.37Å; Q499-V503 PolarHBondContact O-N 3.25Å; I501-V503 PolarHBondContact O-N 3.43Å; V503-D506 PolarHBondContact O-N 3.45Å; V503-L507 HydrophobicContact CG1-CD1 4.23Å; V503-L507 WeakPolarHBondContact O-CG 3.48Å; V503-L507 PolarHBondContact O-N 2.86Å
504S91.1Very high90.1Very high1 Ų159.5 Ų59.51%0.00729%0.292CS..Hα-helixtrans-68.8-33.9177.4-167.90000112.7D500 I501 K502 L507 N508 I529 K530 I531D500-S504 VanDerWaalsContact O-CB 3.26Å; D500-S504 WeakPolarHBondContact O-CB 3.34Å; D500-S504 PolarHBondContact O-N 3.2Å; I501-S504 WeakPolarHBondContact O-CB 3.4Å; I501-S504 PolarHBondContact O-N 3.28Å; I501-S504 VanDerWaalsContact O-N 3.09Å; K502-S504 VanDerWaalsContact C-N 3.27Å; K502-S504 PolarHBondContact O-N 3.44Å; S504-L507 PolarHBondContact O-N 3.19Å; S504-N508 PolarHBondContact O-N 2.92Å; S504-N508 PolarHBondContact O-ND2 2.91Å; S504-I529 PolarHBondContact OG-O 3.24Å; S504-K530 VanDerWaalsContact OG-CA 3.29Å; S504-K530 WeakPolarHBondContact OG-CA 3.41Å; S504-I531 PolarHBondContact OG-N 3.4Å
505E90.5Very high89.4Confident103 Ų10360.3 Ų60.348%0.48130%0.295SS..Hα-helixtrans-65.4-43.5174.3-72.5172.8179.300111.2I501 K502 L507 N508 Q509I501-E505 WeakPolarHBondContact O-CG 3.3Å; I501-E505 PolarHBondContact O-N 2.99Å; K502-E505 WeakPolarHBondContact O-CB 3.43Å; K502-E505 PolarHBondContact O-N 3.03Å; K502-E505 VanDerWaalsContact O-N 3.13Å; E505-L507 PolarHBondContact O-N 3.35Å; E505-N508 WeakPolarHBondContact O-CB 3.44Å; E505-N508 PolarHBondContact O-N 3.19Å; E505-Q509 PolarHBondContact O-N 3.49Å; E505-Q509 VanDerWaalsContact O-N 3.09Å
506D90.8Very high88.5Confident97 Ų9765.5 Ų65.552%0.51931%0.311SS..Hα-helixtrans-60.1-45.5174.5-63.7-24.5000111.2K502 V503 N508 Q509 V510K502-D506 PolarHBondContact O-N 3.36Å; K502-D506 VanDerWaalsContact O-N 3.1Å; V503-D506 PolarHBondContact O-N 3.45Å; D506-N508 VanDerWaalsContact C-N 3.28Å; D506-N508 PolarHBondContact O-N 3.02Å; D506-Q509 PolarHBondContact O-N 3.13Å; D506-Q509 VanDerWaalsContact O-N 3.16Å; D506-V510 WeakPolarHBondContact O-CG2 3.45Å; D506-V510 PolarHBondContact O-N 2.93Å; D506-V510 VanDerWaalsContact O-N 3.12Å
507L89.5Confident87.2Confident26 Ų2667.8 Ų67.814%0.13633%0.327CS..Hα-helixtrans-60.6-36.8176.3-73.9173.3000112.5V503 S504 E505 V510 F511 I531 Y563V503-L507 HydrophobicContact CG1-CD1 4.23Å; V503-L507 WeakPolarHBondContact O-CG 3.48Å; V503-L507 PolarHBondContact O-N 2.86Å; S504-L507 PolarHBondContact O-N 3.19Å; E505-L507 PolarHBondContact O-N 3.35Å; L507-V510 PolarHBondContact O-N 2.97Å; L507-F511 WeakPolarHBondContact O-CB 3.45Å; L507-F511 PolarHBondContact O-N 3.37Å; L507-I531 HydrophobicContact CD1-CD1 4.45Å; L507-Y563 HydrophobicContact CD1-CE2 4.21Å
508N89.4Confident86.1Confident8 Ų872.4 Ų72.44%0.04335%0.352CS..Hα-helixtrans-65.7-39.7175.5-81.7-60.3000112.5S504 E505 D506 F511 K512 N528 I529S504-N508 PolarHBondContact O-N 2.92Å; S504-N508 PolarHBondContact O-ND2 2.91Å; E505-N508 WeakPolarHBondContact O-CB 3.44Å; E505-N508 PolarHBondContact O-N 3.19Å; D506-N508 VanDerWaalsContact C-N 3.28Å; D506-N508 PolarHBondContact O-N 3.02Å; N508-F511 PolarHBondContact O-N 3.43Å; N508-K512 WeakPolarHBondContact O-CB 3.39Å; N508-K512 VanDerWaalsContact O-CG 3.25Å; N508-K512 WeakPolarHBondContact O-CG 3.46Å; N508-K512 PolarHBondContact O-N 3.24Å; N508-N528 PolarHBondContact ND2-OD1 3.28Å; N508-I529 PolarHBondContact ND2-O 3.34Å; N508-I529 WeakPolarHBondContact OD1-CA 3.4Å; N508-I529 WeakPolarHBondContact OD1-CB 3.29Å; N508-I529 PolarHBondContact OD1-N 3.21Å; N508-I529 PolarHBondContact OD1-O 2.92Å
509Q89.1Confident84.8Confident118 Ų11881.7 Ų81.755%0.55139%0.392SS*.Hα-helixtrans-62.2-47.5177.2-67.6177.917.100110.4E505 D506 F511 K512 E513E505-Q509 PolarHBondContact O-N 3.49Å; E505-Q509 VanDerWaalsContact O-N 3.09Å; D506-Q509 PolarHBondContact O-N 3.13Å; D506-Q509 VanDerWaalsContact O-N 3.16Å; Q509-F511 VanDerWaalsContact C-N 3.35Å; Q509-F511 PolarHBondContact O-N 2.65Å; Q509-K512 PolarHBondContact O-N 3.37Å; Q509-E513 WeakPolarHBondContact O-CG 3.47Å; Q509-E513 PolarHBondContact O-N 3.17Å
510V88.7Confident83.6Confident63 Ų6377.7 Ų77.738%0.38237%0.374SS..Hα-helixtrans-61.2-42.8177.1179.40000111.6D506 L507 E513 M514 F562D506-V510 WeakPolarHBondContact O-CG2 3.45Å; D506-V510 PolarHBondContact O-N 2.93Å; D506-V510 VanDerWaalsContact O-N 3.12Å; L507-V510 PolarHBondContact O-N 2.97Å; V510-E513 PolarHBondContact O-N 2.95Å; V510-M514 HydrophobicContact CG1-CG 4.44Å; V510-M514 WeakPolarHBondContact O-CB 3.38Å; V510-M514 VanDerWaalsContact O-CG 3.32Å; V510-M514 WeakPolarHBondContact O-CG 3.44Å; V510-M514 PolarHBondContact O-N 3.04Å; V510-F562 HydrophobicContact CB-CZ 4.22Å; V510-F562 HydrophobicContact CG1-CE2 3.97Å; V510-F562 HydrophobicContact CG1-CZ 3.92Å
511F86.8Confident82.3Confident3 Ų379.4 Ų79.41%0.01339%0.391CS..Hα-helixtrans-60.9-45.6176.6179.7-99.5000111.8L507 N508 Q509 E513 M514 H515 L520 I529 L555 V559 F562L507-F511 WeakPolarHBondContact O-CB 3.45Å; L507-F511 PolarHBondContact O-N 3.37Å; N508-F511 PolarHBondContact O-N 3.43Å; Q509-F511 VanDerWaalsContact C-N 3.35Å; Q509-F511 PolarHBondContact O-N 2.65Å; F511-E513 PolarHBondContact O-N 3.19Å; F511-M514 PolarHBondContact O-N 2.62Å; F511-H515 AromaticContact CD2-CD2 3.89Å; F511-H515 AromaticContact CE2-CD2 3.69Å; F511-H515 AromaticContact CE2-NE2 3.77Å; F511-H515 PolarHBondContact O-CD2 3.42Å; F511-H515 PolarHBondContact O-N 3.28Å; F511-H515 VanDerWaalsContact O-N 3.11Å; F511-L520 HydrophobicContact CZ-CD1 4.39Å; F511-I529 HydrophobicContact CD1-CD1 4Å; F511-I529 HydrophobicContact CE1-CD1 3.97Å; F511-I529 HydrophobicContact CG-CD1 4.37Å; F511-I529 HydrophobicContact CZ-CD1 4.32Å; F511-L555 HydrophobicContact CZ-CD1 4.16Å; F511-V559 HydrophobicContact CE2-CG2 4.01Å; F511-V559 HydrophobicContact CZ-CG2 3.84Å; F511-F562 HydrophobicContact CB-CD1 4.36Å; F511-F562 HydrophobicContact CB-CE1 3.94Å; F511-F562 HydrophobicContact CB-CE2 4.43Å; F511-F562 HydrophobicContact CB-CZ 3.98Å; F511-F562 HydrophobicContact CD2-CB 4.05Å; F511-F562 AromaticContact CD2-CD1 3.75Å; F511-F562 HydrophobicContact CD2-CD1 3.75Å; F511-F562 HydrophobicContact CD2-CD2 4.13Å; F511-F562 HydrophobicContact CD2-CE1 4.21Å; F511-F562 AromaticContact CD2-CG 3.71Å; F511-F562 HydrophobicContact CD2-CG 3.71Å; F511-F562 HydrophobicContact CE2-CB 4.24Å; F511-F562 HydrophobicContact CE2-CG 4.39Å; F511-F562 HydrophobicContact CG-CD1 4.5Å
512K86.4Confident81.3Confident54 Ų5480.7 Ų80.724%0.23540%0.398CS..Hα-helixtrans-62.8-41.8178.5-74.1176.9-178.6-167.70112.3N508 Q509 H515 K516 D525 V527N508-K512 WeakPolarHBondContact O-CB 3.39Å; N508-K512 VanDerWaalsContact O-CG 3.25Å; N508-K512 WeakPolarHBondContact O-CG 3.46Å; N508-K512 PolarHBondContact O-N 3.24Å; Q509-K512 PolarHBondContact O-N 3.37Å; K512-H515 PolarHBondContact O-N 3Å; K512-K516 WeakPolarHBondContact O-CB 3.3Å; K512-K516 PolarHBondContact O-N 3.4Å; K512-D525 PolarHBondContact NZ-O 3.38Å; K512-V527 WeakPolarHBondContact CE-O 3.31Å; K512-V527 PolarHBondContact NZ-O 3.22Å
513E85.1Confident80.5Confident139 Ų13980 Ų8065%0.6540%0.404SS*.Hα-helixtrans-64-46.5177-73179.1171.700112.1Q509 V510 F511 H515 K516Q509-E513 WeakPolarHBondContact O-CG 3.47Å; Q509-E513 PolarHBondContact O-N 3.17Å; V510-E513 PolarHBondContact O-N 2.95Å; F511-E513 PolarHBondContact O-N 3.19Å; E513-H515 VanDerWaalsContact C-N 3.29Å; E513-H515 PolarHBondContact O-N 3.19Å; E513-K516 WeakPolarHBondContact O-CB 3.34Å; E513-K516 PolarHBondContact O-N 2.88Å
514M82Confident79.4Confident111 Ų11177.1 Ų77.155%0.54739%0.388SS..Hα-helixtrans-62-35179.6-78.1-66.9-59.700113.1V510 F511V510-M514 HydrophobicContact CG1-CG 4.44Å; V510-M514 WeakPolarHBondContact O-CB 3.38Å; V510-M514 VanDerWaalsContact O-CG 3.32Å; V510-M514 WeakPolarHBondContact O-CG 3.44Å; V510-M514 PolarHBondContact O-N 3.04Å; F511-M514 PolarHBondContact O-N 2.62Å
515H77.8Confident78.6Confident19 Ų1982.4 Ų82.49%0.08842%0.416CS..THydrogen-bonded Turntrans-102.29.3-177.3-71-98.1000114.1F511 K512 E513 H517 N518 L520 A524 E558F511-H515 AromaticContact CD2-CD2 3.89Å; F511-H515 AromaticContact CE2-CD2 3.69Å; F511-H515 AromaticContact CE2-NE2 3.77Å; F511-H515 PolarHBondContact O-CD2 3.42Å; F511-H515 PolarHBondContact O-N 3.28Å; F511-H515 VanDerWaalsContact O-N 3.11Å; K512-H515 PolarHBondContact O-N 3Å; E513-H515 VanDerWaalsContact C-N 3.29Å; E513-H515 PolarHBondContact O-N 3.19Å; H515-H517 PolarHBondContact O-N 3.43Å; H515-N518 PolarHBondContact O-N 3Å; H515-L520 HydrophobicContact CB-CD1 3.53Å; H515-L520 HydrophobicContact CB-CG 4.22Å; H515-A524 HydrophobicContact CB-CB 4.05Å; H515-E558 IonicContact CE1-OE2 3.42Å; H515-E558 PolarHBondContact CE1-OE2 3.18Å
516K72.1Confident78.1Confident147 Ų14781.2 Ų81.264%0.63942%0.419SS*.SBendtrans-61.4-29.5179.1-164.4173.3-176.7174.90113.6K512 E513K512-K516 WeakPolarHBondContact O-CB 3.3Å; K512-K516 PolarHBondContact O-N 3.4Å; E513-K516 WeakPolarHBondContact O-CB 3.34Å; E513-K516 PolarHBondContact O-N 2.88Å
517H66.1Low77.7Confident175 Ų17577.7 Ų77.781%0.8140%0.401SS*.SBendtrans-108.6-6.7-179.7-64.4-68.6000113.8H515H515-H517 PolarHBondContact O-N 3.43Å
518N68.9Low77.6Confident97 Ų9781.4 Ų81.452%0.51942%0.421SS..SBendtrans-84.6141.8176.6-80.4-21.5000110.5H515 L520H515-N518 PolarHBondContact O-N 3Å; N518-L520 VanDerWaalsContact C-N 3.3Å; N518-L520 PolarHBondContact O-N 2.81Å
519K64.7Low77.6Confident217 Ų21782 Ų8294%0.94342%0.424SS*.  trans-78.179.4172.4-70.2-174.4-180-179.70110
520L67.9Low77.6Confident35 Ų3579.6 Ų79.618%0.18341%0.412CS..  trans-72.7156.5165-73.1176000110.6F511 H515 N518 L522 A524 L555 E558F511-L520 HydrophobicContact CZ-CD1 4.39Å; H515-L520 HydrophobicContact CB-CD1 3.53Å; H515-L520 HydrophobicContact CB-CG 4.22Å; N518-L520 VanDerWaalsContact C-N 3.3Å; N518-L520 PolarHBondContact O-N 2.81Å; L520-L522 WeakPolarHBondContact CB-O 3.3Å; L520-L522 PolarHBondContact O-N 3.19Å; L520-A524 HydrophobicContact CD1-CB 4.13Å; L520-L555 HydrophobicContact CD1-CD1 4.29Å; L520-L555 HydrophobicContact CD2-CD1 4.43Å; L520-E558 HydrophobicContact CD2-CB 4.26Å; L520-E558 HydrophobicContact CD2-CG 3.84Å
521A66.4Low77.7Confident59 Ų5978 Ų7849%0.48840%0.401SS..SBendtrans-61.2-29.6173.600000112.7D554A521-D554 HydrophobicContact CB-CB 4.22Å
522L71.1Confident77.8Confident46 Ų4680.1 Ų80.124%0.24141%0.412CS..SBendtrans-121146.6172.8-70.6169.7000110.5L520 A524 V527 E551 L552L520-L522 WeakPolarHBondContact CB-O 3.3Å; L520-L522 PolarHBondContact O-N 3.19Å; L522-A524 PolarHBondContact O-N 3.15Å; L522-V527 HydrophobicContact CB-CG2 4.4Å; L522-V527 HydrophobicContact CD1-CG2 4.44Å; L522-E551 HydrophobicContact CD1-CB 4.1Å; L522-E551 HydrophobicContact CD2-CB 4.17Å; L522-E551 HydrophobicContact CG-CB 4.01Å; L522-L552 HydrophobicContact CD1-CD2 3.85Å
523P74.4Confident78Confident91 Ų9181.1 Ų81.159%0.59142%0.42SS*.  trans-55.9126.6171.1-22.132.6000110.2D525 S526P523-D525 PolarHBondContact O-N 3.08Å; P523-D525 VanDerWaalsContact O-N 3.07Å; P523-S526 WeakPolarHBondContact O-CB 3.3Å; P523-S526 PolarHBondContact O-N 3.39Å; P523-S526 PolarHBondContact O-OG 3.12Å
524A69.1Low77.9Confident10 Ų1077.2 Ų77.28%0.08341%0.411CS..G310 helixtrans-53.7-34.6-177.700000112.3H515 L520 L522 S526 V527H515-A524 HydrophobicContact CB-CB 4.05Å; L520-A524 HydrophobicContact CD1-CB 4.13Å; L522-A524 PolarHBondContact O-N 3.15Å; A524-S526 PolarHBondContact O-N 2.91Å; A524-V527 PolarHBondContact O-N 2.76Å
525D73.8Confident77.9Confident112 Ų11274.5 Ų74.560%0.59941%0.412SS*.G310 helixtrans-64.4-24.2178.3-68.4-25.9000114.1K512 P523 V527K512-D525 PolarHBondContact NZ-O 3.38Å; P523-D525 PolarHBondContact O-N 3.08Å; P523-D525 VanDerWaalsContact O-N 3.07Å; D525-V527 VanDerWaalsContact C-N 3.32Å
526S78.9Confident78.2Confident78 Ų7873.7 Ų73.755%0.54541%0.408SS..G310 helixtrans-80.9-10.2-178.570.70000114.1P523 A524P523-S526 WeakPolarHBondContact O-CB 3.3Å; P523-S526 PolarHBondContact O-N 3.39Å; P523-S526 PolarHBondContact O-OG 3.12Å; A524-S526 PolarHBondContact O-N 2.91Å
527V83.2Confident78.6Confident24 Ų2467.3 Ų67.315%0.14538%0.381CS..  trans-108.3140.1-177-171.80000110.6K512 L522 A524 D525 I529 L555K512-V527 WeakPolarHBondContact CE-O 3.31Å; K512-V527 PolarHBondContact NZ-O 3.22Å; L522-V527 HydrophobicContact CB-CG2 4.4Å; L522-V527 HydrophobicContact CD1-CG2 4.44Å; A524-V527 PolarHBondContact O-N 2.76Å; D525-V527 VanDerWaalsContact C-N 3.32Å; V527-I529 HydrophobicContact CG1-CD1 4.41Å; V527-I529 HydrophobicContact CG1-CG1 3.83Å; V527-L555 HydrophobicContact CB-CD2 4.19Å; V527-L555 HydrophobicContact CG1-CD2 3.74Å; V527-L555 HydrophobicContact CG2-CD2 3.63Å
528N87.4Confident78.6Confident104 Ų10461.3 Ų61.356%0.55636%0.358SS*.  trans-129.1118.1171.8-171.812000109.3N508N508-N528 PolarHBondContact ND2-OD1 3.28Å
529I88.9Confident78.1Confident20 Ų2066.5 Ų66.510%0.10337%0.37CS..  trans-110.2117.2-171.9-54.1162000108.8S504 N508 F511 V527 I531 V559S504-I529 PolarHBondContact OG-O 3.24Å; N508-I529 PolarHBondContact ND2-O 3.34Å; N508-I529 WeakPolarHBondContact OD1-CA 3.4Å; N508-I529 WeakPolarHBondContact OD1-CB 3.29Å; N508-I529 PolarHBondContact OD1-N 3.21Å; N508-I529 PolarHBondContact OD1-O 2.92Å; F511-I529 HydrophobicContact CD1-CD1 4Å; F511-I529 HydrophobicContact CE1-CD1 3.97Å; F511-I529 HydrophobicContact CG-CD1 4.37Å; F511-I529 HydrophobicContact CZ-CD1 4.32Å; V527-I529 HydrophobicContact CG1-CD1 4.41Å; V527-I529 HydrophobicContact CG1-CG1 3.83Å; I529-I531 HydrophobicContact CG2-CD1 4.33Å; I529-I531 HydrophobicContact CG2-CG1 3.84Å; I529-V559 HydrophobicContact CD1-CB 4.23Å; I529-V559 HydrophobicContact CD1-CG1 3.81Å; I529-V559 HydrophobicContact CD1-CG2 3.32Å; I529-V559 HydrophobicContact CG1-CG2 4.39Å; I529-V559 HydrophobicContact CG2-CG1 4.06Å
530K90Very high77.8Confident68 Ų6858.9 Ų58.930%0.29634%0.344SS..  trans-96.6101.7177-67.3-172.8175.6-176.10110.7L463 I464 I501 S504 L532L463-K530 PolarHBondContact O-NZ 3.38Å; I464-K530 PolarHBondContact O-NZ 3.17Å; I501-K530 HydrophobicContact CD1-CD 4.42Å; S504-K530 VanDerWaalsContact OG-CA 3.29Å; S504-K530 WeakPolarHBondContact OG-CA 3.41Å; K530-L532 HydrophobicContact CB-CD1 4.48Å; K530-L532 HydrophobicContact CB-CG 4.4Å
531I90.3Very high77Confident28 Ų2862.4 Ų62.414%0.14437%0.372CS..  trans-96110.1177.7-55.2-177.4000109.1S504 L507 I529 Y563 L572S504-I531 PolarHBondContact OG-N 3.4Å; L507-I531 HydrophobicContact CD1-CD1 4.45Å; I529-I531 HydrophobicContact CG2-CD1 4.33Å; I529-I531 HydrophobicContact CG2-CG1 3.84Å; I531-Y563 HydrophobicContact CD1-CD2 3.39Å; I531-Y563 HydrophobicContact CD1-CE2 3.76Å; I531-Y563 HydrophobicContact CD1-CG 4.15Å; I531-Y563 HydrophobicContact CG2-CD2 4.34Å; I531-Y563 HydrophobicContact CG2-CE2 3.69Å; I531-L572 HydrophobicContact CG2-CD2 3.84Å
532L90.4Very high76.7Confident48 Ų4863.3 Ų63.325%0.25137%0.366SS..  trans-122149.3-169-54.2175.9000111.6I464 D500 I501 K530 A534 W537I464-L532 HydrophobicContact CD1-CD1 4.07Å; I464-L532 HydrophobicContact CG1-CD1 3.81Å; D500-L532 HydrophobicContact CB-CD2 4.16Å; I501-L532 HydrophobicContact CD1-CD2 3.91Å; K530-L532 HydrophobicContact CB-CD1 4.48Å; K530-L532 HydrophobicContact CB-CG 4.4Å; L532-A534 PolarHBondContact O-N 3.41Å; L532-W537 HydrophobicContact CB-CD2 4.16Å; L532-W537 HydrophobicContact CB-CG 3.98Å; L532-W537 HydrophobicContact CD1-CD2 3.82Å; L532-W537 HydrophobicContact CD1-CE3 3.79Å; L532-W537 HydrophobicContact CD1-CG 4.4Å; L532-W537 HydrophobicContact CD1-CH2 4.11Å; L532-W537 HydrophobicContact CD1-CZ2 4.12Å; L532-W537 HydrophobicContact CD1-CZ3 3.96Å; L532-W537 HydrophobicContact CD2-CH2 4.38Å; L532-W537 HydrophobicContact CD2-CZ2 3.8Å; L532-W537 HydrophobicContact CG-CD2 4.4Å; L532-W537 HydrophobicContact CG-CZ2 4.45Å
533N88.8Confident76.4Confident76 Ų7668.4 Ų68.441%0.40639%0.386SS..  trans-76.7114.2179.2-176.5-13.5000111.7D500 G535 A536 W537D500-N533 VanDerWaalsContact OD2-CB 3.3Å; D500-N533 WeakPolarHBondContact OD2-CB 3.33Å; D500-N533 PolarHBondContact OD2-N 3.47Å; N533-G535 PolarHBondContact O-N 2.85Å; N533-G535 PolarHBondContact OD1-N 3.2Å; N533-A536 HydrophobicContact CB-CB 4.49Å; N533-A536 PolarHBondContact O-N 3.42Å; N533-W537 VanDerWaalsContact O-CD1 3.28Å; N533-W537 PolarHBondContact O-N 3.19Å
534A83.7Confident76.5Confident56 Ų5665.1 Ų65.146%0.46337%0.365SS..THydrogen-bonded Turntrans-59.2-15.8179.100000115.3L532 W537L532-A534 PolarHBondContact O-N 3.41Å; A534-W537 CarbonylContact C-O 3.54Å
535G82.8Confident77Confident54 Ų5471.5 Ų71.556%0.55739%0.391SS*.THydrogen-bonded Turntrans-81.2-32.8173.900000113.7N533N533-G535 PolarHBondContact O-N 2.85Å; N533-G535 PolarHBondContact OD1-N 3.2Å
536A82.8Confident77.5Confident2 Ų267 Ų672%0.01737%0.367CS..THydrogen-bonded Turntrans-88.3-42.1178.800000111.1K456 R496 M497 N533K456-A536 WeakPolarHBondContact CE-O 3.29Å; K456-A536 PolarHBondContact NZ-O 3Å; R496-A536 HydrophobicContact CB-CB 4.44Å; R496-A536 HydrophobicContact CG-CB 4.17Å; M497-A536 HydrophobicContact CG-CB 4.45Å; N533-A536 HydrophobicContact CB-CB 4.49Å; N533-A536 PolarHBondContact O-N 3.42Å
537W81.8Confident77.9Confident14 Ų1465.3 Ų65.35%0.05336%0.356CS..SBendtrans-91.1115.3178.8-59.977.3000108.5T460 L463 I464 M497 D500 I501 L532 N533 A534 R539T460-W537 HydrophobicContact CG2-CE3 3.78Å; T460-W537 HydrophobicContact CG2-CZ3 4.1Å; L463-W537 HydrophobicContact CB-CH2 3.58Å; L463-W537 HydrophobicContact CB-CZ3 4.08Å; L463-W537 HydrophobicContact CD1-CH2 3.64Å; L463-W537 HydrophobicContact CD1-CZ2 4.23Å; L463-W537 HydrophobicContact CD1-CZ3 4.43Å; L463-W537 HydrophobicContact CG-CH2 4.27Å; I464-W537 HydrophobicContact CD1-CE3 4.05Å; I464-W537 HydrophobicContact CD1-CZ3 3.98Å; I464-W537 HydrophobicContact CG1-CE3 4.23Å; I464-W537 HydrophobicContact CG1-CH2 4.43Å; I464-W537 HydrophobicContact CG1-CZ3 3.69Å; M497-W537 HydrophobicContact CB-CD2 4.39Å; M497-W537 HydrophobicContact CB-CH2 4.06Å; M497-W537 HydrophobicContact CB-CZ2 3.46Å; M497-W537 VanDerWaalsContact CB-CZ2 3.46Å; M497-W537 HydrophobicContact CE-CD2 4.11Å; M497-W537 HydrophobicContact CE-CE3 3.78Å; M497-W537 HydrophobicContact CE-CH2 4Å; M497-W537 HydrophobicContact CE-CZ2 4.32Å; M497-W537 HydrophobicContact CE-CZ3 3.7Å; M497-W537 HydrophobicContact CG-CD2 3.89Å; M497-W537 HydrophobicContact CG-CE3 4.5Å; M497-W537 HydrophobicContact CG-CG 4.24Å; M497-W537 HydrophobicContact CG-CZ2 3.91Å; M497-W537 VanDerWaalsContact O-CZ2 3.28Å; M497-W537 WeakPolarHBondContact O-CZ2 3.15Å; D500-W537 HydrophobicContact CB-CZ2 4.47Å; D500-W537 VanDerWaalsContact OD2-CD1 3.28Å; D500-W537 PolarHBondContact OD2-NE1 3.07Å; I501-W537 HydrophobicContact CD1-CH2 3.79Å; I501-W537 HydrophobicContact CD1-CZ2 4.02Å; I501-W537 HydrophobicContact CG1-CH2 3.88Å; I501-W537 HydrophobicContact CG1-CZ2 3.85Å; L532-W537 HydrophobicContact CB-CD2 4.16Å; L532-W537 HydrophobicContact CB-CG 3.98Å; L532-W537 HydrophobicContact CD1-CD2 3.82Å; L532-W537 HydrophobicContact CD1-CE3 3.79Å; L532-W537 HydrophobicContact CD1-CG 4.4Å; L532-W537 HydrophobicContact CD1-CH2 4.11Å; L532-W537 HydrophobicContact CD1-CZ2 4.12Å; L532-W537 HydrophobicContact CD1-CZ3 3.96Å; L532-W537 HydrophobicContact CD2-CH2 4.38Å; L532-W537 HydrophobicContact CD2-CZ2 3.8Å; L532-W537 HydrophobicContact CG-CD2 4.4Å; L532-W537 HydrophobicContact CG-CZ2 4.45Å; N533-W537 VanDerWaalsContact O-CD1 3.28Å; N533-W537 PolarHBondContact O-N 3.19Å; A534-W537 CarbonylContact C-O 3.54Å; W537-R539 PolarHBondContact O-N 3.37Å
538S64.9Low78.1Confident48 Ų4865.5 Ų65.534%0.33636%0.355SS..  trans-50.3138.6-168.6-170.80000112.5R453 S540R453-S538 PolarHBondContact NH2-OG 3.3Å; R453-S538 VanDerWaalsContact NH2-OG 3.14Å; S538-S540 PolarHBondContact O-N 3.26Å
539R59.6Low77.9Confident207 Ų20760.8 Ų60.878%0.78133%0.331SS*.  trans-71.4108.7170.4-59.9-175-168.8-169.13.9108.5W537 S541W537-R539 PolarHBondContact O-N 3.37Å; R539-S541 PolarHBondContact O-N 3.33Å
540S56.8Low77.7Confident56 Ų5663.5 Ų63.539%0.39235%0.348SS..  trans-64.3123.9151.541.30000106.5S538 E542 H575S538-S540 PolarHBondContact O-N 3.26Å; S540-E542 PolarHBondContact O-N 3Å; S540-H575 PolarHBondContact OG-CD2 2.94Å; S540-H575 VanDerWaalsContact OG-CD2 3.25Å; S540-H575 PolarHBondContact OG-NE2 2.98Å
541S52.3Low77.3Confident110 Ų11063.6 Ų63.677%0.76935%0.35SS*.SBendtrans-71.4-19.8-179.847.30000112.2R539R539-S541 PolarHBondContact O-N 3.33Å
542E59.7Low77.1Confident77 Ų7764.6 Ų64.636%0.3636%0.355SS..  trans-92.8106.2-173.8-155.4170.2-153.100111.3S540 V544 R699S540-E542 PolarHBondContact O-N 3Å; E542-V544 PolarHBondContact O-N 2.96Å; E542-R699 IonicContact OE1-CZ 3.04Å; E542-R699 VanDerWaalsContact OE1-CZ 3.32Å; E542-R699 IonicContact OE1-NH1 3Å; E542-R699 PolarHBondContact OE1-NH1 3.34Å; E542-R699 VanDerWaalsContact OE1-NH1 3.14Å; E542-R699 IonicContact OE1-NH2 3.47Å; E542-R699 PolarHBondContact OE1-NH2 3.33Å; E542-R699 IonicContact OE2-CZ 2.7Å; E542-R699 IonicContact OE2-NE 2.71Å; E542-R699 IonicContact OE2-NH1 3.43Å; E542-R699 PolarHBondContact OE2-NH1 2.91Å; E542-R699 VanDerWaalsContact OE2-NH1 3.13Å; E542-R699 IonicContact OE2-NH2 3.57Å; E542-R699 PolarHBondContact OE2-NH2 3.41Å
543K65.9Low76.8Confident154 Ų15467.8 Ų67.867%0.6737%0.369SS*.  trans-75107.8163.8-70.2-176.1-179.9-177.70108F545K543-F545 HydrophobicContact CB-CE2 4.49Å; K543-F545 PolarHBondContact O-N 3.23Å
544V75.4Confident76.7Confident22 Ų2268.5 Ų68.513%0.13337%0.373CS..  trans-85109.1168.3-176.20000107.5E542 F599 L626 P627E542-V544 PolarHBondContact O-N 2.96Å; V544-F599 HydrophobicContact CB-CZ 3.81Å; V544-F599 HydrophobicContact CG1-CE1 4.08Å; V544-F599 HydrophobicContact CG1-CE2 4.02Å; V544-F599 HydrophobicContact CG1-CZ 3.46Å; V544-F599 VanDerWaalsContact CG1-CZ 3.46Å; V544-F599 HydrophobicContact CG2-CZ 4.41Å; V544-L626 HydrophobicContact CG1-CD2 4.01Å; V544-P627 HydrophobicContact CG1-CG 3.98Å
545F78.8Confident76.8Confident144 Ų14466.5 Ų66.563%0.63235%0.354SS*.  trans-69.5140.5171-64.5-80.6000109.2K543K543-F545 HydrophobicContact CB-CE2 4.49Å; K543-F545 PolarHBondContact O-N 3.23Å
546V85.6Confident77Confident17 Ų1765.6 Ų65.610%0.10334%0.336CS..  trans-150.5132.5176.159.80000108.7L548 H576 F599 A602 T624 L626V546-L548 HydrophobicContact CG1-CD2 3.9Å; V546-L548 PolarHBondContact O-N 3.28Å; V546-H576 HydrophobicContact CG1-CB 3.77Å; V546-F599 HydrophobicContact CB-CD1 4.26Å; V546-F599 HydrophobicContact CB-CE1 4.19Å; V546-F599 HydrophobicContact CG1-CD1 4.3Å; V546-F599 HydrophobicContact CG1-CE1 4.04Å; V546-F599 HydrophobicContact CG2-CD1 4.15Å; V546-A602 HydrophobicContact CG2-CB 3.63Å; V546-T624 WeakPolarHBondContact CA-O 3.15Å; V546-L626 HydrophobicContact CB-CD2 3.84Å; V546-L626 HydrophobicContact CG2-CD2 3.83Å; V546-L626 HydrophobicContact CG2-CG 4.14Å
547S87.3Confident77.3Confident43 Ų4368.6 Ų68.630%0.30136%0.355SS..PPolyproline II helixtrans-75.1118.7169.6-47.30000108.8A602 T624 E625S547-A602 WeakPolarHBondContact O-CB 3.44Å; S547-T624 PolarHBondContact N-O 3.22Å; S547-E625 WeakPolarHBondContact OG-CG 2.99Å
548L86.4Confident77.5Confident27 Ų2771.8 Ų71.814%0.14137%0.371CS..PPolyproline II helixtrans-89.4156.4-179.3-61.3175.2000110.5V546 L552 I556 T598V546-L548 HydrophobicContact CG1-CD2 3.9Å; V546-L548 PolarHBondContact O-N 3.28Å; L548-L552 HydrophobicContact CB-CB 4.33Å; L548-I556 HydrophobicContact CD1-CD1 3.47Å; L548-I556 VanDerWaalsContact CD1-CD1 3.47Å; L548-T598 HydrophobicContact CD2-CG2 3.41Å; L548-T598 VanDerWaalsContact CD2-CG2 3.41Å
549P84.8Confident78.6Confident6 Ų669.6 Ų69.64%0.03936%0.355CS..PPolyproline II helixtrans-59.7149.5166.9-29.341.2000112.3E551 L552 E553 L601 F605P549-E551 VanDerWaalsContact CB-OE2 3.32Å; P549-E551 WeakPolarHBondContact CB-OE2 3.19Å; P549-E551 PolarHBondContact O-N 3.2Å; P549-E551 VanDerWaalsContact O-N 3.14Å; P549-L552 PolarHBondContact O-N 2.84Å; P549-E553 PolarHBondContact O-N 3.39Å; P549-L601 VanDerWaalsContact CD-CD2 3.44Å; P549-L601 HydrophobicContact CG-CD2 3.36Å; P549-L601 HydrophobicContact CG-CG 4.49Å; P549-F605 HydrophobicContact CB-CD1 3.92Å; P549-F605 HydrophobicContact CB-CD2 3.73Å; P549-F605 HydrophobicContact CB-CE1 3.92Å; P549-F605 HydrophobicContact CB-CE2 3.71Å; P549-F605 HydrophobicContact CB-CG 3.82Å; P549-F605 HydrophobicContact CB-CZ 3.81Å; P549-F605 HydrophobicContact CG-CB 3.81Å; P549-F605 HydrophobicContact CG-CD1 4.02Å; P549-F605 HydrophobicContact CG-CD2 3.77Å; P549-F605 HydrophobicContact CG-CE2 4.28Å; P549-F605 HydrophobicContact CG-CG 3.6Å
550T83.4Confident80.1Confident76 Ų7663.5 Ų63.547%0.46634%0.336SS..Hα-helixtrans-53.3-38.4-177.7-48.30000112L552 E553 D554T550-L552 PolarHBondContact O-N 3.29Å; T550-E553 PolarHBondContact O-N 3.02Å; T550-D554 WeakPolarHBondContact O-CB 3.16Å; T550-D554 VanDerWaalsContact O-CG 3.28Å; T550-D554 PolarHBondContact O-N 2.98Å
551E82.6Confident81.6Confident71 Ų7164.4 Ų64.433%0.33234%0.336SS..Hα-helixtrans-63.1-29179.6-56.589.2162.100113.4L522 P549 F605L522-E551 HydrophobicContact CD1-CB 4.1Å; L522-E551 HydrophobicContact CD2-CB 4.17Å; L522-E551 HydrophobicContact CG-CB 4.01Å; P549-E551 VanDerWaalsContact CB-OE2 3.32Å; P549-E551 WeakPolarHBondContact CB-OE2 3.19Å; P549-E551 PolarHBondContact O-N 3.2Å; P549-E551 VanDerWaalsContact O-N 3.14Å; E551-F605 WeakPolarHBondContact OE2-CE2 3.41Å; E551-F605 WeakPolarHBondContact OE2-CZ 3.29Å
552L84.8Confident83.3Confident48 Ų4859.9 Ų59.925%0.25130%0.303SS..Hα-helixtrans-90.1-34.1175.1-66.1-178.5000112L522 L548 P549 T550 L555 I556 L601L522-L552 HydrophobicContact CD1-CD2 3.85Å; L548-L552 HydrophobicContact CB-CB 4.33Å; P549-L552 PolarHBondContact O-N 2.84Å; T550-L552 PolarHBondContact O-N 3.29Å; L552-L555 WeakPolarHBondContact O-CB 3.29Å; L552-L555 PolarHBondContact O-N 3.33Å; L552-I556 PolarHBondContact O-N 3.49Å; L552-L601 HydrophobicContact CD1-CD1 4.48Å; L552-L601 HydrophobicContact CD1-CD2 3.78Å
553E85.3Confident84.7Confident116 Ų11657.2 Ų57.254%0.54229%0.29SS..Hα-helixtrans-63.6-42.8177.4-169173-166.700111.3P549 T550 L555 I556 P557P549-E553 PolarHBondContact O-N 3.39Å; T550-E553 PolarHBondContact O-N 3.02Å; E553-L555 PolarHBondContact O-N 3.06Å; E553-I556 PolarHBondContact O-N 2.92Å; E553-P557 WeakPolarHBondContact O-CD 3.48Å
554D86.3Confident85.8Confident91 Ų9156.8 Ų56.849%0.48729%0.288SS..THydrogen-bonded Turntrans-65.2-26.3176-69.7-18.7000112.6A521 T550A521-D554 HydrophobicContact CB-CB 4.22Å; T550-D554 WeakPolarHBondContact O-CB 3.16Å; T550-D554 VanDerWaalsContact O-CG 3.28Å; T550-D554 PolarHBondContact O-N 2.98Å
555L85.3Confident86.4Confident14 Ų1465.1 Ų65.17%0.07332%0.317CS..Hα-helixtrans-79.9-32.3-178.4-176.267.3000112.8F511 L520 V527 L552 E553 E558 V559F511-L555 HydrophobicContact CZ-CD1 4.16Å; L520-L555 HydrophobicContact CD1-CD1 4.29Å; L520-L555 HydrophobicContact CD2-CD1 4.43Å; V527-L555 HydrophobicContact CB-CD2 4.19Å; V527-L555 HydrophobicContact CG1-CD2 3.74Å; V527-L555 HydrophobicContact CG2-CD2 3.63Å; L552-L555 WeakPolarHBondContact O-CB 3.29Å; L552-L555 PolarHBondContact O-N 3.33Å; E553-L555 PolarHBondContact O-N 3.06Å; L555-E558 PolarHBondContact O-N 3.17Å; L555-V559 HydrophobicContact CD1-CG2 4.41Å; L555-V559 HydrophobicContact CG-CG2 4.16Å; L555-V559 WeakPolarHBondContact O-CG2 3.28Å; L555-V559 PolarHBondContact O-N 3.23Å; L555-V559 VanDerWaalsContact O-N 3.15Å
556I87.8Confident86.7Confident34 Ų3462.2 Ų62.217%0.17431%0.308CS..Hα-helixtrans-56.4-49.6-175.8-77.5168.2000112.3L548 L552 E553 E558 V559 E560 W574L548-I556 HydrophobicContact CD1-CD1 3.47Å; L548-I556 VanDerWaalsContact CD1-CD1 3.47Å; L552-I556 PolarHBondContact O-N 3.49Å; E553-I556 PolarHBondContact O-N 2.92Å; I556-E558 VanDerWaalsContact C-N 3.34Å; I556-E558 PolarHBondContact O-N 2.79Å; I556-V559 PolarHBondContact O-N 2.76Å; I556-E560 HydrophobicContact CG2-CG 4.46Å; I556-E560 WeakPolarHBondContact O-CG 3.41Å; I556-E560 PolarHBondContact O-N 2.7Å; I556-W574 HydrophobicContact CB-CZ2 4.07Å; I556-W574 HydrophobicContact CG1-CD2 4.31Å; I556-W574 HydrophobicContact CG1-CH2 4.06Å; I556-W574 HydrophobicContact CG1-CZ2 3.86Å; I556-W574 HydrophobicContact CG1-CZ3 4.39Å; I556-W574 HydrophobicContact CG2-CZ2 3.76Å
557P88.4Confident86.8Confident66 Ų6663.9 Ų63.943%0.42931%0.314SS..Hα-helixtrans-59.7-40.1178.2-25.634.5000113.5E553 V559 E560 D561E553-P557 WeakPolarHBondContact O-CD 3.48Å; P557-V559 VanDerWaalsContact C-N 3.31Å; P557-V559 PolarHBondContact O-N 3.45Å; P557-E560 PolarHBondContact O-N 2.85Å; P557-D561 WeakPolarHBondContact O-CB 3.24Å; P557-D561 PolarHBondContact O-N 3.14Å
558E87.1Confident86.7Confident80 Ų8067.1 Ų67.137%0.37434%0.337SS..Hα-helixtrans-62.1-40.5178.7-67.1-68.8151.500111.4H515 L520 L555 I556 F562H515-E558 IonicContact CE1-OE2 3.42Å; H515-E558 PolarHBondContact CE1-OE2 3.18Å; L520-E558 HydrophobicContact CD2-CB 4.26Å; L520-E558 HydrophobicContact CD2-CG 3.84Å; L555-E558 PolarHBondContact O-N 3.17Å; I556-E558 VanDerWaalsContact C-N 3.34Å; I556-E558 PolarHBondContact O-N 2.79Å; E558-F562 VanDerWaalsContact O-CB 3.31Å; E558-F562 WeakPolarHBondContact O-CB 3.42Å; E558-F562 PolarHBondContact O-N 2.93Å
559V87.8Confident86.7Confident2 Ų270.1 Ų70.11%0.01238%0.375CS..Hα-helixtrans-68.5-41.8175.7176.10000111.4F511 I529 L555 I556 P557 F562 Y563 L572 W574F511-V559 HydrophobicContact CE2-CG2 4.01Å; F511-V559 HydrophobicContact CZ-CG2 3.84Å; I529-V559 HydrophobicContact CD1-CB 4.23Å; I529-V559 HydrophobicContact CD1-CG1 3.81Å; I529-V559 HydrophobicContact CD1-CG2 3.32Å; I529-V559 HydrophobicContact CG1-CG2 4.39Å; I529-V559 HydrophobicContact CG2-CG1 4.06Å; L555-V559 HydrophobicContact CD1-CG2 4.41Å; L555-V559 HydrophobicContact CG-CG2 4.16Å; L555-V559 WeakPolarHBondContact O-CG2 3.28Å; L555-V559 PolarHBondContact O-N 3.23Å; L555-V559 VanDerWaalsContact O-N 3.15Å; I556-V559 PolarHBondContact O-N 2.76Å; P557-V559 VanDerWaalsContact C-N 3.31Å; P557-V559 PolarHBondContact O-N 3.45Å; V559-F562 PolarHBondContact O-N 2.77Å; V559-Y563 WeakPolarHBondContact O-CB 3.47Å; V559-Y563 PolarHBondContact O-N 3.4Å; V559-L572 HydrophobicContact CG1-CD1 4.44Å; V559-W574 HydrophobicContact CB-CH2 3.98Å; V559-W574 HydrophobicContact CB-CZ2 4.19Å; V559-W574 HydrophobicContact CG1-CH2 3.77Å; V559-W574 HydrophobicContact CG1-CZ2 4.11Å; V559-W574 HydrophobicContact CG2-CH2 4.41Å
560E89.5Confident86.8Confident79 Ų7977.2 Ų77.237%0.36940%0.4SS..Hα-helixtrans-63.2-42.9177.3-73.1-173.3175.800111.8I556 P557 Y563 K564 L572 W574I556-E560 HydrophobicContact CG2-CG 4.46Å; I556-E560 WeakPolarHBondContact O-CG 3.41Å; I556-E560 PolarHBondContact O-N 2.7Å; P557-E560 PolarHBondContact O-N 2.85Å; E560-Y563 PolarHBondContact O-N 3.44Å; E560-K564 WeakPolarHBondContact O-CB 3.11Å; E560-K564 PolarHBondContact O-N 2.59Å; E560-L572 HydrophobicContact CG-CD1 4.18Å; E560-W574 HydrophobicContact CG-CZ2 4.25Å; E560-W574 PolarHBondContact OE1-NE1 2.73Å
561D88.6Confident86.9Confident75 Ų7581.7 Ų81.740%0.40141%0.413SS..Hα-helixtrans-67.7-43.8177.4-86.8-8.4000112.1P557 Y563 K564 R565P557-D561 WeakPolarHBondContact O-CB 3.24Å; P557-D561 PolarHBondContact O-N 3.14Å; D561-Y563 VanDerWaalsContact C-N 3.33Å; D561-Y563 PolarHBondContact O-N 3.48Å; D561-K564 PolarHBondContact O-N 3.02Å; D561-R565 VanDerWaalsContact O-CG 3.26Å; D561-R565 WeakPolarHBondContact O-CG 3.36Å; D561-R565 PolarHBondContact O-N 3.32Å
562F88.1Confident87.1Confident16 Ų1679.9 Ų79.97%0.0741%0.406CS..Hα-helixtrans-55.2-49.6172.2168.3-102.5000111.3V510 F511 E558 V559 R565 N566V510-F562 HydrophobicContact CB-CZ 4.22Å; V510-F562 HydrophobicContact CG1-CE2 3.97Å; V510-F562 HydrophobicContact CG1-CZ 3.92Å; F511-F562 HydrophobicContact CB-CD1 4.36Å; F511-F562 HydrophobicContact CB-CE1 3.94Å; F511-F562 HydrophobicContact CB-CE2 4.43Å; F511-F562 HydrophobicContact CB-CZ 3.98Å; F511-F562 HydrophobicContact CD2-CB 4.05Å; F511-F562 AromaticContact CD2-CD1 3.75Å; F511-F562 HydrophobicContact CD2-CD1 3.75Å; F511-F562 HydrophobicContact CD2-CD2 4.13Å; F511-F562 HydrophobicContact CD2-CE1 4.21Å; F511-F562 AromaticContact CD2-CG 3.71Å; F511-F562 HydrophobicContact CD2-CG 3.71Å; F511-F562 HydrophobicContact CE2-CB 4.24Å; F511-F562 HydrophobicContact CE2-CG 4.39Å; F511-F562 HydrophobicContact CG-CD1 4.5Å; E558-F562 VanDerWaalsContact O-CB 3.31Å; E558-F562 WeakPolarHBondContact O-CB 3.42Å; E558-F562 PolarHBondContact O-N 2.93Å; V559-F562 PolarHBondContact O-N 2.77Å; F562-R565 PolarHBondContact O-N 3.45Å; F562-N566 VanDerWaalsContact CE2-ND2 3.29Å; F562-N566 WeakPolarHBondContact CE2-ND2 3.44Å; F562-N566 WeakPolarHBondContact CZ-ND2 3.44Å; F562-N566 PolarHBondContact O-N 2.84Å
563Y89.7Confident87.2Confident21 Ų2183.8 Ų83.88%0.08242%0.423CS..Hα-helixtrans-67.2-40.3-178.3-167.8-102.2000112.2L507 I531 V559 E560 D561 R565 N566 H567 R570 L572L507-Y563 HydrophobicContact CD1-CE2 4.21Å; I531-Y563 HydrophobicContact CD1-CD2 3.39Å; I531-Y563 HydrophobicContact CD1-CE2 3.76Å; I531-Y563 HydrophobicContact CD1-CG 4.15Å; I531-Y563 HydrophobicContact CG2-CD2 4.34Å; I531-Y563 HydrophobicContact CG2-CE2 3.69Å; V559-Y563 WeakPolarHBondContact O-CB 3.47Å; V559-Y563 PolarHBondContact O-N 3.4Å; E560-Y563 PolarHBondContact O-N 3.44Å; D561-Y563 VanDerWaalsContact C-N 3.33Å; D561-Y563 PolarHBondContact O-N 3.48Å; Y563-R565 VanDerWaalsContact C-N 3.34Å; Y563-R565 PolarHBondContact O-N 3.08Å; Y563-N566 PolarHBondContact O-N 3.45Å; Y563-H567 HydrophobicContact CD1-CB 4.42Å; Y563-H567 AromaticContact CD2-CD2 3.68Å; Y563-H567 HydrophobicContact CE1-CB 4.05Å; Y563-H567 AromaticContact CE2-CD2 3.3Å; Y563-H567 WeakPolarHBondContact CE2-CD2 3.41Å; Y563-H567 AromaticContact CE2-NE2 3.96Å; Y563-H567 AromaticContact CZ-CD2 3.63Å; Y563-H567 WeakPolarHBondContact O-CB 3.5Å; Y563-H567 PolarHBondContact O-N 2.88Å; Y563-R570 HydrophobicContact CE1-CB 3.86Å; Y563-R570 PolarHBondContact OH-NH1 3.03Å; Y563-L572 HydrophobicContact CD1-CD1 4.08Å; Y563-L572 HydrophobicContact CD1-CD2 3.65Å; Y563-L572 HydrophobicContact CD1-CG 3.79Å; Y563-L572 HydrophobicContact CE1-CD2 3.73Å; Y563-L572 HydrophobicContact CE1-CG 4.32Å; Y563-L572 HydrophobicContact CG-CD1 4.01Å; Y563-L572 HydrophobicContact CG-CD2 4.06Å; Y563-L572 HydrophobicContact CG-CG 4.22Å
564K90Very high87.2Confident144 Ų14482.7 Ų82.763%0.62641%0.413SS*.Hα-helixtrans-65.3-35.4179.4-174.5-179.8179.6-174.50112.6E560 D561 H567E560-K564 WeakPolarHBondContact O-CB 3.11Å; E560-K564 PolarHBondContact O-N 2.59Å; D561-K564 PolarHBondContact O-N 3.02Å; K564-H567 CarbonylContact O-C 3.54Å
565R87.8Confident87.2Confident198 Ų19881.9 Ų81.975%0.74741%0.407SS*.Hα-helixtrans-64.5-41.2174.6-73.7172.9-169.9177.67.5111.8D561 F562 Y563D561-R565 VanDerWaalsContact O-CG 3.26Å; D561-R565 WeakPolarHBondContact O-CG 3.36Å; D561-R565 PolarHBondContact O-N 3.32Å; F562-R565 PolarHBondContact O-N 3.45Å; Y563-R565 VanDerWaalsContact C-N 3.34Å; Y563-R565 PolarHBondContact O-N 3.08Å
566N85Confident87.2Confident82 Ų8282.8 Ų82.844%0.43941%0.411SS..Hα-helixtrans-83.9-24.7-178.1-65.8-18.2000113.1F562 Y563F562-N566 VanDerWaalsContact CE2-ND2 3.29Å; F562-N566 WeakPolarHBondContact CE2-ND2 3.44Å; F562-N566 WeakPolarHBondContact CZ-ND2 3.44Å; F562-N566 PolarHBondContact O-N 2.84Å; Y563-N566 PolarHBondContact O-N 3.45Å
567H86.4Confident86.9Confident52 Ų5282.9 Ų82.924%0.24141%0.411CS..SBendtrans-138.789.7-175.7-58.8-66.5000112.1Y563 K564 R570Y563-H567 HydrophobicContact CD1-CB 4.42Å; Y563-H567 AromaticContact CD2-CD2 3.68Å; Y563-H567 HydrophobicContact CE1-CB 4.05Å; Y563-H567 AromaticContact CE2-CD2 3.3Å; Y563-H567 WeakPolarHBondContact CE2-CD2 3.41Å; Y563-H567 AromaticContact CE2-NE2 3.96Å; Y563-H567 AromaticContact CZ-CD2 3.63Å; Y563-H567 WeakPolarHBondContact O-CB 3.5Å; Y563-H567 PolarHBondContact O-N 2.88Å; K564-H567 CarbonylContact O-C 3.54Å; H567-R570 HydrophobicContact CB-CG 4.4Å
568S86.9Confident86.6Confident112 Ų11280.9 Ų80.978%0.78340%0.397SS*.THydrogen-bonded Turntrans-67143.1174.961.80000112R570S568-R570 VanDerWaalsContact C-N 3.35Å; S568-R570 PolarHBondContact O-N 3.48Å
569G85.3Confident86.6Confident90 Ų9079.2 Ų79.293%0.92839%0.394SS*.THydrogen-bonded Turntrans80.35.1176.900000116
570R87.3Confident86.7Confident154 Ų15482.6 Ų82.658%0.58141%0.411SS*.  trans-105.4151.7175.3-59.6-171.1-173.8175.6-0.2111.5Y563 H567 S568Y563-R570 HydrophobicContact CE1-CB 3.86Å; Y563-R570 PolarHBondContact OH-NH1 3.03Å; H567-R570 HydrophobicContact CB-CG 4.4Å; S568-R570 VanDerWaalsContact C-N 3.35Å; S568-R570 PolarHBondContact O-N 3.48Å
571K85Confident86.7Confident170 Ų17079.8 Ų79.874%0.73940%0.404SS*.  trans-127128.9177.1-174.9176.1-178.2175.60110.7H573K571-H573 PolarHBondContact O-ND1 2.95Å
572L87.8Confident86.8Confident34 Ų3480.9 Ų80.918%0.17841%0.409CS..  trans-79.2147.9175.9-64.9-178.7000111.3I531 V559 E560 Y563I531-L572 HydrophobicContact CG2-CD2 3.84Å; V559-L572 HydrophobicContact CG1-CD1 4.44Å; E560-L572 HydrophobicContact CG-CD1 4.18Å; Y563-L572 HydrophobicContact CD1-CD1 4.08Å; Y563-L572 HydrophobicContact CD1-CD2 3.65Å; Y563-L572 HydrophobicContact CD1-CG 3.79Å; Y563-L572 HydrophobicContact CE1-CD2 3.73Å; Y563-L572 HydrophobicContact CE1-CG 4.32Å; Y563-L572 HydrophobicContact CG-CD1 4.01Å; Y563-L572 HydrophobicContact CG-CD2 4.06Å; Y563-L572 HydrophobicContact CG-CG 4.22Å
573H85.6Confident86.9Confident129 Ų12982 Ų8260%0.59742%0.415SS*.  trans-132.1116.6174.4-67.180.6000107.6K571K571-H573 PolarHBondContact O-ND1 2.95Å
574W86Confident87Confident93 Ų9384.6 Ų84.635%0.35243%0.433SS..  trans-80.4132.2-176.9-63.395.2000111.4I556 V559 E560I556-W574 HydrophobicContact CB-CZ2 4.07Å; I556-W574 HydrophobicContact CG1-CD2 4.31Å; I556-W574 HydrophobicContact CG1-CH2 4.06Å; I556-W574 HydrophobicContact CG1-CZ2 3.86Å; I556-W574 HydrophobicContact CG1-CZ3 4.39Å; I556-W574 HydrophobicContact CG2-CZ2 3.76Å; V559-W574 HydrophobicContact CB-CH2 3.98Å; V559-W574 HydrophobicContact CB-CZ2 4.19Å; V559-W574 HydrophobicContact CG1-CH2 3.77Å; V559-W574 HydrophobicContact CG1-CZ2 4.11Å; V559-W574 HydrophobicContact CG2-CH2 4.41Å; E560-W574 HydrophobicContact CG-CZ2 4.25Å; E560-W574 PolarHBondContact OE1-NE1 2.73Å
575H85.8Confident87.1Confident74 Ų7478.7 Ų78.734%0.34341%0.408SS..  trans-119.774.1-177.6-169.1-69.1000111.1S540 L577 M578 S579S540-H575 PolarHBondContact OG-CD2 2.94Å; S540-H575 VanDerWaalsContact OG-CD2 3.25Å; S540-H575 PolarHBondContact OG-NE2 2.98Å; H575-L577 VanDerWaalsContact C-N 3.26Å; H575-L577 PolarHBondContact O-N 3.44Å; H575-M578 VanDerWaalsContact CE1-CG 3.41Å; H575-M578 WeakPolarHBondContact CE1-CG 3.12Å; H575-M578 WeakPolarHBondContact ND1-CG 3.34Å; H575-M578 PolarHBondContact ND1-N 2.79Å; H575-M578 PolarHBondContact O-N 3.34Å; H575-S579 PolarHBondContact O-OG 3.38Å
576H85.4Confident87.1Confident34 Ų3476.4 Ų76.416%0.15740%0.403CS..G310 helixtrans-62.4-25.4-172.4-56.9-57.7000114.9V546 M578 S579 T598 F599V546-H576 HydrophobicContact CG1-CB 3.77Å; H576-M578 PolarHBondContact O-N 3.31Å; H576-S579 WeakPolarHBondContact O-CB 3.42Å; H576-S579 PolarHBondContact O-N 3.1Å; H576-S579 VanDerWaalsContact O-N 3.1Å; H576-T598 HydrophobicContact CB-CG2 4.11Å; H576-F599 HydrophobicContact CB-CE1 4.08Å
577L82Confident87.3Confident36 Ų3673.6 Ų73.619%0.18839%0.388CS..G310 helixtrans-59.1-33.7178172.867.8000112.9H575 F599 Q694H575-L577 VanDerWaalsContact C-N 3.26Å; H575-L577 PolarHBondContact O-N 3.44Å; L577-F599 HydrophobicContact CB-CE2 4.24Å; L577-F599 HydrophobicContact CB-CZ 3.88Å; L577-F599 HydrophobicContact CD1-CD2 4.34Å; L577-F599 HydrophobicContact CD1-CE2 3.54Å; L577-F599 HydrophobicContact CD1-CZ 4.07Å; L577-Q694 PolarHBondContact O-NE2 2.96Å
578M81.8Confident87.4Confident24 Ų2477.1 Ų77.112%0.11840%0.404CS..G310 helixtrans-97.53.1-179.5-66-71179.900112.6R461 I464 H575 H576 M700R461-M578 HydrophobicContact CG-CE 4.19Å; R461-M578 HydrophobicContact CG-SD 4.47Å; I464-M578 HydrophobicContact CD1-CB 4.45Å; I464-M578 HydrophobicContact CD1-CG 4.49Å; I464-M578 HydrophobicContact CG2-CB 3.94Å; H575-M578 VanDerWaalsContact CE1-CG 3.41Å; H575-M578 WeakPolarHBondContact CE1-CG 3.12Å; H575-M578 WeakPolarHBondContact ND1-CG 3.34Å; H575-M578 PolarHBondContact ND1-N 2.79Å; H575-M578 PolarHBondContact O-N 3.34Å; H576-M578 PolarHBondContact O-N 3.31Å; M578-M700 HydrophobicContact CE-CE 4.18Å
579S87.5Confident87.4Confident45 Ų4574 Ų7432%0.31538%0.38SS..  trans-88.4146.8177.6-61.20000110.6H575 H576 T598 Q694H575-S579 PolarHBondContact O-OG 3.38Å; H576-S579 WeakPolarHBondContact O-CB 3.42Å; H576-S579 PolarHBondContact O-N 3.1Å; H576-S579 VanDerWaalsContact O-N 3.1Å; S579-T598 VanDerWaalsContact C-OG1 3.31Å; S579-T598 WeakPolarHBondContact CB-OG1 3.28Å; S579-T598 PolarHBondContact O-N 3.34Å; S579-T598 VanDerWaalsContact O-N 3.11Å; S579-T598 PolarHBondContact O-OG1 3.44Å; S579-Q694 PolarHBondContact O-NE2 3.25Å
580N89.3Confident87.5Confident72 Ų7270.5 Ų70.539%0.38534%0.344SS..EExtended strand (participates in β ladder)trans-140.1167.1177.161.816.4000110V596 I690N580-V596 CarbonylContact C-O 3.58Å; N580-V596 WeakPolarHBondContact CA-O 3.37Å; N580-V596 WeakPolarHBondContact CB-O 3.29Å; N580-I690 HydrophobicContact CB-CD1 3.66Å
581G89.4Confident87.7Confident20 Ų2066.6 Ų66.621%0.20633%0.333CS..EExtended strand (participates in β ladder)trans-158.7164.4-179.800000111.9E595 V596G581-E595 WeakPolarHBondContact O-CA 3.48Å; G581-V596 PolarHBondContact N-O 2.97Å; G581-V596 PolarHBondContact O-N 3.46Å
582I90.8Very high88Confident99 Ų9958.5 Ų58.551%0.50830%0.298SS..EExtended strand (participates in β ladder)trans-109.4123.3173.7-58.7172.3000107.4D593 L594 E595I582-D593 HydrophobicContact CG2-CB 4.03Å; I582-L594 CarbonylContact C-O 3.47Å; I582-L594 WeakPolarHBondContact CA-O 3.42Å; I582-E595 HydrophobicContact CG1-CB 4.23Å; I582-E595 HydrophobicContact CG1-CG 4.32Å
583I91Very high88.3Confident40 Ų4059.7 Ų59.721%0.20530%0.304CS..EExtended strand (participates in β ladder)trans-116147.4175.464.7173.6000110.3D593 L594 V596 L601 L604I583-D593 CarbonylContact O-C 3.31Å; I583-D593 WeakPolarHBondContact O-CA 3.36Å; I583-L594 HydrophobicContact CG1-CB 3.96Å; I583-L594 PolarHBondContact N-O 3.44Å; I583-L594 PolarHBondContact O-N 2.88Å; I583-V596 HydrophobicContact CD1-CG2 4.09Å; I583-V596 HydrophobicContact CG1-CG2 4.04Å; I583-V596 HydrophobicContact CG2-CG2 4.31Å; I583-L601 HydrophobicContact CG2-CD1 3.58Å; I583-L601 HydrophobicContact CG2-CG 4.13Å; I583-L604 HydrophobicContact CD1-CB 4.28Å; I583-L604 HydrophobicContact CD1-CD1 3.57Å
584T91.3Very high88.6Confident75 Ų7553.6 Ų53.646%0.4628%0.276SS..EExtended strand (participates in β ladder)trans-90108.1172.3-66.50000109.5K586 Q591 D593T584-K586 HydrophobicContact CG2-CG 4.22Å; T584-Q591 VanDerWaalsContact CG2-CD 3.49Å; T584-Q591 HydrophobicContact CG2-CG 3.36Å; T584-D593 PolarHBondContact OG1-OD1 2.89Å
585F90.8Very high88.8Confident20 Ų2051.4 Ų51.49%0.08827%0.27CS..EExtended strand (participates in β ladder)trans-90115.2175.8-179-98.7000110.6N587 Q591 Y592 L594 V648 V669 F673F585-N587 HydrophobicContact CE1-CB 3.99Å; F585-N587 HydrophobicContact CZ-CB 4.49Å; F585-Q591 WeakPolarHBondContact O-CA 3.17Å; F585-Y592 HydrophobicContact CD1-CD2 4.28Å; F585-Y592 PolarHBondContact N-O 2.92Å; F585-Y592 PolarHBondContact O-N 3.41Å; F585-L594 HydrophobicContact CB-CD1 3.49Å; F585-L594 VanDerWaalsContact CB-CD1 3.49Å; F585-L594 HydrophobicContact CB-CG 3.7Å; F585-L594 HydrophobicContact CD1-CD1 4.41Å; F585-L594 HydrophobicContact CD2-CD1 4.07Å; F585-L594 HydrophobicContact CG-CD1 3.75Å; F585-L594 HydrophobicContact CG-CG 4.41Å; F585-V648 HydrophobicContact CD2-CG1 4.39Å; F585-V648 HydrophobicContact CE2-CG1 3.97Å; F585-V648 HydrophobicContact CZ-CG1 4.11Å; F585-V669 HydrophobicContact CE2-CG1 3.57Å; F585-V669 HydrophobicContact CZ-CG1 3.42Å; F585-V669 VanDerWaalsContact CZ-CG1 3.42Å; F585-F673 AromaticContact CD1-CD1 3.93Å; F585-F673 HydrophobicContact CD1-CD1 3.93Å; F585-F673 HydrophobicContact CD1-CE1 4.28Å; F585-F673 HydrophobicContact CE1-CB 4.16Å; F585-F673 AromaticContact CE1-CD1 3.66Å; F585-F673 HydrophobicContact CE1-CD1 3.66Å; F585-F673 HydrophobicContact CE1-CE1 4.4Å; F585-F673 HydrophobicContact CE1-CG 4.17Å
586K89.4Confident89.1Confident150 Ų15047.9 Ų47.965%0.65225%0.253SS*.EExtended strand (participates in β ladder)trans-105.1132.5177.5-68.1179.8-178.3174.10110.1T584 Q591T584-K586 HydrophobicContact CG2-CG 4.22Å; K586-Q591 HydrophobicContact CG-CB 4.39Å; K586-Q591 HydrophobicContact CG-CG 4.01Å
587N88.2Confident89.3Confident22 Ų2246.6 Ų46.612%0.11825%0.248CC..  trans-138.5-174.8172.172.6-3.1000111.1F585 V589 G590 Q671 F673F585-N587 HydrophobicContact CE1-CB 3.99Å; F585-N587 HydrophobicContact CZ-CB 4.49Å; N587-V589 PolarHBondContact O-N 3.34Å; N587-V589 PolarHBondContact OD1-N 2.79Å; N587-G590 PolarHBondContact N-O 3.12Å; N587-G590 PolarHBondContact O-N 2.88Å; N587-G590 PolarHBondContact OD1-N 2.75Å; N587-G590 PolarHBondContact OD1-O 2.78Å; N587-Q671 PolarHBondContact ND2-O 3.23Å; N587-F673 WeakPolarHBondContact ND2-CB 3.28Å; N587-F673 PolarHBondContact ND2-N 3.48Å; N587-F673 PolarHBondContact ND2-O 3.43Å
588E88Confident89.7Confident126 Ų12645.3 Ų45.359%0.58924%0.242SC*.SBendtrans-65.1-23.5-179-64.5-176.2173.600113.5R612 Q671E588-R612 IonicContact OE1-CZ 2.89Å; E588-R612 IonicContact OE1-NE 2.65Å; E588-R612 IonicContact OE1-NH2 3.14Å; E588-R612 PolarHBondContact OE1-NH2 2.63Å; E588-Q671 HydrophobicContact CG-CB 4.14Å
589V87.9Confident90.1Very high46 Ų4644.4 Ų44.428%0.27924%0.237SC..SBendtrans-86.9-37-178.9-176.90000112.4N587 V681N587-V589 PolarHBondContact O-N 3.34Å; N587-V589 PolarHBondContact OD1-N 2.79Å; V589-V681 HydrophobicContact CG1-CG1 3.9Å
590G87.8Confident90.3Very high17 Ų1742.2 Ų42.218%0.17522%0.222CC..  trans174.8-162-172.200000115.1N587 K683N587-G590 PolarHBondContact N-O 3.12Å; N587-G590 PolarHBondContact O-N 2.88Å; N587-G590 PolarHBondContact OD1-N 2.75Å; N587-G590 PolarHBondContact OD1-O 2.78Å; G590-K683 VanDerWaalsContact CA-O 3.29Å; G590-K683 WeakPolarHBondContact CA-O 3.45Å
591Q91.5Very high90.3Very high72 Ų7239.8 Ų39.834%0.33621%0.209SC..EExtended strand (participates in β ladder)trans-128.7121.7-175.7-179.8-180-23.700109.8T584 F585 K586 K683 R684T584-Q591 VanDerWaalsContact CG2-CD 3.49Å; T584-Q591 HydrophobicContact CG2-CG 3.36Å; F585-Q591 WeakPolarHBondContact O-CA 3.17Å; K586-Q591 HydrophobicContact CG-CB 4.39Å; K586-Q591 HydrophobicContact CG-CG 4.01Å; Q591-K683 PolarHBondContact N-O 2.73Å; Q591-R684 VanDerWaalsContact O-CA 3.25Å; Q591-R684 WeakPolarHBondContact O-CA 2.96Å
592Y91.8Very high90.4Very high0 Ų039.1 Ų39.10%020%0.201CC..EExtended strand (participates in β ladder)trans-125.4139-174.7-51.7-87.3000110.7F585 F673 S674 L675 Q682 G685F585-Y592 HydrophobicContact CD1-CD2 4.28Å; F585-Y592 PolarHBondContact N-O 2.92Å; F585-Y592 PolarHBondContact O-N 3.41Å; Y592-F673 HydrophobicContact CD1-CE1 4.42Å; Y592-F673 AromaticContact CD2-CD1 3.8Å; Y592-F673 HydrophobicContact CD2-CD1 3.8Å; Y592-F673 AromaticContact CD2-CE1 3.81Å; Y592-F673 HydrophobicContact CD2-CE1 3.81Å; Y592-F673 AromaticContact CE2-CD1 3.94Å; Y592-F673 HydrophobicContact CE2-CD1 3.94Å; Y592-F673 HydrophobicContact CE2-CE1 4.27Å; Y592-F673 HydrophobicContact CG-CD1 4.35Å; Y592-F673 AromaticContact CG-CE1 3.89Å; Y592-F673 HydrophobicContact CG-CE1 3.89Å; Y592-F673 PolarHBondContact OH-O 2.97Å; Y592-S674 VanDerWaalsContact OH-CA 3.28Å; Y592-S674 WeakPolarHBondContact OH-CA 3.27Å; Y592-S674 WeakPolarHBondContact OH-CB 3.35Å; Y592-L675 HydrophobicContact CD1-CB 4.3Å; Y592-L675 HydrophobicContact CE1-CB 4Å; Y592-Q682 VanDerWaalsContact CE1-O 3.27Å; Y592-Q682 WeakPolarHBondContact CE1-O 3.32Å; Y592-Q682 PolarHBondContact OH-O 2.92Å; Y592-G685 CarbonylContact C-O 3.5Å; Y592-G685 VanDerWaalsContact CA-O 3.32Å; Y592-G685 WeakPolarHBondContact CA-O 3.47Å
593D92.5Very high90.5Very high60 Ų6034.4 Ų34.432%0.32118%0.177SC..EExtended strand (participates in β ladder)trans-91.1113.1174.3-62.4-30.3000108.7I582 I583 T584 G685 K686 I687I582-D593 HydrophobicContact CG2-CB 4.03Å; I583-D593 CarbonylContact O-C 3.31Å; I583-D593 WeakPolarHBondContact O-CA 3.36Å; T584-D593 PolarHBondContact OG1-OD1 2.89Å; D593-G685 PolarHBondContact N-O 3.37Å; D593-K686 HydrophobicContact CB-CB 4.38Å; D593-K686 HydrophobicContact CB-CG 4.27Å; D593-K686 CarbonylContact O-C 3.54Å; D593-K686 VanDerWaalsContact O-CA 3.28Å; D593-K686 WeakPolarHBondContact O-CA 3.39Å; D593-I687 PolarHBondContact O-N 2.88Å
594L92Very high90.5Very high0 Ų033.4 Ų33.40%017%0.172CC..EExtended strand (participates in β ladder)trans-100.1118179.7-54.4-175.6000109.1I582 I583 F585 V596 L604 V648 F673 I687 L689I582-L594 CarbonylContact C-O 3.47Å; I582-L594 WeakPolarHBondContact CA-O 3.42Å; I583-L594 HydrophobicContact CG1-CB 3.96Å; I583-L594 PolarHBondContact N-O 3.44Å; I583-L594 PolarHBondContact O-N 2.88Å; F585-L594 HydrophobicContact CB-CD1 3.49Å; F585-L594 VanDerWaalsContact CB-CD1 3.49Å; F585-L594 HydrophobicContact CB-CG 3.7Å; F585-L594 HydrophobicContact CD1-CD1 4.41Å; F585-L594 HydrophobicContact CD2-CD1 4.07Å; F585-L594 HydrophobicContact CG-CD1 3.75Å; F585-L594 HydrophobicContact CG-CG 4.41Å; L594-V596 HydrophobicContact CB-CG1 3.95Å; L594-L604 HydrophobicContact CD1-CD1 4.48Å; L594-V648 HydrophobicContact CD1-CG1 4.08Å; L594-V648 HydrophobicContact CD1-CG2 4.25Å; L594-F673 HydrophobicContact CD2-CE1 4.42Å; L594-F673 HydrophobicContact CD2-CZ 4.45Å; L594-I687 HydrophobicContact CD2-CB 4Å; L594-I687 HydrophobicContact CD2-CD1 4.13Å; L594-I687 HydrophobicContact CD2-CG1 4.48Å; L594-L689 HydrophobicContact CB-CD1 4.16Å; L594-L689 HydrophobicContact CD1-CD1 3.94Å; L594-L689 HydrophobicContact CD2-CD1 4.04Å; L594-L689 HydrophobicContact CG-CD1 4.27Å
595E91.1Very high90.5Very high47 Ų4732.9 Ų32.922%0.2216%0.163CC..EExtended strand (participates in β ladder)trans-86.5113.6167.9-179.3-173.7179.400108.1G581 I582 I687 N688 L689 I690G581-E595 WeakPolarHBondContact O-CA 3.48Å; I582-E595 HydrophobicContact CG1-CB 4.23Å; I582-E595 HydrophobicContact CG1-CG 4.32Å; E595-I687 PolarHBondContact N-O 3.18Å; E595-N688 HydrophobicContact CB-CB 4.37Å; E595-N688 PolarHBondContact OE1-ND2 3.21Å; E595-N688 WeakPolarHBondContact OE2-CB 3.3Å; E595-N688 PolarHBondContact OE2-ND2 3Å; E595-L689 PolarHBondContact O-N 2.92Å; E595-I690 HydrophobicContact CG-CD1 3.73Å; E595-I690 HydrophobicContact CG-CG1 4.33Å
596V90.9Very high90.4Very high0 Ų032.7 Ų32.70%017%0.166CC..EExtended strand (participates in β ladder)trans-133.2155.6-167.6-70.70000110.7N580 G581 I583 L594 Q600 L601 L604 L689N580-V596 CarbonylContact C-O 3.58Å; N580-V596 WeakPolarHBondContact CA-O 3.37Å; N580-V596 WeakPolarHBondContact CB-O 3.29Å; G581-V596 PolarHBondContact N-O 2.97Å; G581-V596 PolarHBondContact O-N 3.46Å; I583-V596 HydrophobicContact CD1-CG2 4.09Å; I583-V596 HydrophobicContact CG1-CG2 4.04Å; I583-V596 HydrophobicContact CG2-CG2 4.31Å; L594-V596 HydrophobicContact CB-CG1 3.95Å; V596-Q600 HydrophobicContact CB-CB 3.83Å; V596-Q600 HydrophobicContact CG1-CB 4.23Å; V596-L601 HydrophobicContact CG2-CB 4.02Å; V596-L604 HydrophobicContact CG1-CD1 4.3Å; V596-L689 HydrophobicContact CG1-CB 4.1Å; V596-L689 HydrophobicContact CG1-CD1 3.99Å
597T90.8Very high90.6Very high7 Ų725.9 Ų25.94%0.04314%0.136CC..EExtended strand (participates in β ladder)trans-70.3159.7168.462.10000110.8F599 Q600 L601 I690 L693 Q694T597-F599 PolarHBondContact O-N 2.96Å; T597-Q600 PolarHBondContact O-N 3.34Å; T597-Q600 VanDerWaalsContact O-N 3.14Å; T597-Q600 WeakPolarHBondContact OG1-CB 3.17Å; T597-Q600 VanDerWaalsContact OG1-CG 3.3Å; T597-Q600 WeakPolarHBondContact OG1-CG 3.48Å; T597-Q600 PolarHBondContact OG1-N 2.99Å; T597-Q600 PolarHBondContact OG1-OE1 3.36Å; T597-Q600 VanDerWaalsContact OG1-OE1 3.11Å; T597-L601 WeakPolarHBondContact O-CB 3.22Å; T597-L601 PolarHBondContact O-N 3.38Å; T597-I690 HydrophobicContact CG2-CB 4.31Å; T597-I690 HydrophobicContact CG2-CG1 4.16Å; T597-I690 HydrophobicContact CG2-CG2 3.92Å; T597-L693 HydrophobicContact CG2-CB 4.25Å; T597-L693 HydrophobicContact CG2-CD1 4.37Å; T597-Q694 HydrophobicContact CG2-CG 3.75Å
598T89.8Confident90.5Very high9 Ų929.3 Ų29.36%0.05516%0.155CC..Hα-helixtrans-59.3-31.9176.2-600000112.8L548 H576 S579 L601 A602L548-T598 HydrophobicContact CD2-CG2 3.41Å; L548-T598 VanDerWaalsContact CD2-CG2 3.41Å; H576-T598 HydrophobicContact CB-CG2 4.11Å; S579-T598 VanDerWaalsContact C-OG1 3.31Å; S579-T598 WeakPolarHBondContact CB-OG1 3.28Å; S579-T598 PolarHBondContact O-N 3.34Å; S579-T598 VanDerWaalsContact O-N 3.11Å; S579-T598 PolarHBondContact O-OG1 3.44Å; T598-L601 WeakPolarHBondContact O-CB 3.33Å; T598-L601 PolarHBondContact O-N 3.3Å; T598-A602 PolarHBondContact O-N 3.29Å
599F90.2Very high90.4Very high5 Ų532.4 Ų32.42%0.02217%0.169CC..Hα-helixtrans-69.8-42.8175.3-61.6-12.5000112.2V544 V546 H576 L577 T597 L601 A602 V603 L626 T634V544-F599 HydrophobicContact CB-CZ 3.81Å; V544-F599 HydrophobicContact CG1-CE1 4.08Å; V544-F599 HydrophobicContact CG1-CE2 4.02Å; V544-F599 HydrophobicContact CG1-CZ 3.46Å; V544-F599 VanDerWaalsContact CG1-CZ 3.46Å; V544-F599 HydrophobicContact CG2-CZ 4.41Å; V546-F599 HydrophobicContact CB-CD1 4.26Å; V546-F599 HydrophobicContact CB-CE1 4.19Å; V546-F599 HydrophobicContact CG1-CD1 4.3Å; V546-F599 HydrophobicContact CG1-CE1 4.04Å; V546-F599 HydrophobicContact CG2-CD1 4.15Å; H576-F599 HydrophobicContact CB-CE1 4.08Å; L577-F599 HydrophobicContact CB-CE2 4.24Å; L577-F599 HydrophobicContact CB-CZ 3.88Å; L577-F599 HydrophobicContact CD1-CD2 4.34Å; L577-F599 HydrophobicContact CD1-CE2 3.54Å; L577-F599 HydrophobicContact CD1-CZ 4.07Å; T597-F599 PolarHBondContact O-N 2.96Å; F599-L601 VanDerWaalsContact C-N 3.26Å; F599-L601 PolarHBondContact O-N 3.46Å; F599-A602 PolarHBondContact O-N 2.99Å; F599-V603 WeakPolarHBondContact O-CG2 3.45Å; F599-V603 PolarHBondContact O-N 3.18Å; F599-L626 HydrophobicContact CB-CD1 4.05Å; F599-L626 HydrophobicContact CB-CD2 4.42Å; F599-L626 HydrophobicContact CD1-CD2 3.72Å; F599-L626 HydrophobicContact CD2-CD2 4.2Å; F599-L626 HydrophobicContact CE1-CD2 3.95Å; F599-L626 HydrophobicContact CE2-CD2 4.39Å; F599-L626 HydrophobicContact CG-CD1 4.39Å; F599-L626 HydrophobicContact CG-CD2 3.87Å; F599-L626 HydrophobicContact CZ-CD2 4.29Å; F599-T634 HydrophobicContact CB-CG2 4.06Å
600Q91.1Very high90.5Very high0 Ų034.8 Ų34.80%017%0.173CC..Hα-helixtrans-61.7-38.4172.8-75.4171.1-47.700111.2V596 T597 V603 L604 T634 S637 L638 L689 L693V596-Q600 HydrophobicContact CB-CB 3.83Å; V596-Q600 HydrophobicContact CG1-CB 4.23Å; T597-Q600 PolarHBondContact O-N 3.34Å; T597-Q600 VanDerWaalsContact O-N 3.14Å; T597-Q600 WeakPolarHBondContact OG1-CB 3.17Å; T597-Q600 VanDerWaalsContact OG1-CG 3.3Å; T597-Q600 WeakPolarHBondContact OG1-CG 3.48Å; T597-Q600 PolarHBondContact OG1-N 2.99Å; T597-Q600 PolarHBondContact OG1-OE1 3.36Å; T597-Q600 VanDerWaalsContact OG1-OE1 3.11Å; Q600-V603 PolarHBondContact O-N 3.07Å; Q600-L604 WeakPolarHBondContact O-CB 3.39Å; Q600-L604 VanDerWaalsContact O-CG 3.28Å; Q600-L604 WeakPolarHBondContact O-CG 3.5Å; Q600-L604 PolarHBondContact O-N 2.96Å; Q600-T634 HydrophobicContact CB-CG2 4.25Å; Q600-T634 HydrophobicContact CG-CG2 3.71Å; Q600-S637 PolarHBondContact NE2-OG 2.84Å; Q600-L638 HydrophobicContact CB-CD2 4.37Å; Q600-L638 HydrophobicContact CG-CD1 4.42Å; Q600-L638 HydrophobicContact CG-CD2 4.14Å; Q600-L638 HydrophobicContact CG-CG 4.25Å; Q600-L689 PolarHBondContact NE2-O 2.98Å; Q600-L693 HydrophobicContact CG-CD1 4.14Å
601L91.1Very high90.3Very high21 Ų2137.1 Ų37.111%0.1119%0.185CC..Hα-helixtrans-63.8-46.4177.3179.5149.4000111.6P549 L552 I583 V596 T597 T598 F599 V603 L604 F605P549-L601 VanDerWaalsContact CD-CD2 3.44Å; P549-L601 HydrophobicContact CG-CD2 3.36Å; P549-L601 HydrophobicContact CG-CG 4.49Å; L552-L601 HydrophobicContact CD1-CD1 4.48Å; L552-L601 HydrophobicContact CD1-CD2 3.78Å; I583-L601 HydrophobicContact CG2-CD1 3.58Å; I583-L601 HydrophobicContact CG2-CG 4.13Å; V596-L601 HydrophobicContact CG2-CB 4.02Å; T597-L601 WeakPolarHBondContact O-CB 3.22Å; T597-L601 PolarHBondContact O-N 3.38Å; T598-L601 WeakPolarHBondContact O-CB 3.33Å; T598-L601 PolarHBondContact O-N 3.3Å; F599-L601 VanDerWaalsContact C-N 3.26Å; F599-L601 PolarHBondContact O-N 3.46Å; L601-V603 VanDerWaalsContact C-N 3.34Å; L601-V603 PolarHBondContact O-N 3.41Å; L601-L604 PolarHBondContact O-N 3.06Å; L601-F605 WeakPolarHBondContact O-CB 3.43Å; L601-F605 PolarHBondContact O-N 2.92Å
602A90.9Very high90Very high6 Ų643 Ų435%0.0520%0.204CC..Hα-helixtrans-58.9-44.2174.500000112.1V546 S547 T598 F599 F605 T624V546-A602 HydrophobicContact CG2-CB 3.63Å; S547-A602 WeakPolarHBondContact O-CB 3.44Å; T598-A602 PolarHBondContact O-N 3.29Å; F599-A602 PolarHBondContact O-N 2.99Å; A602-F605 PolarHBondContact O-N 3.11Å; A602-T624 HydrophobicContact CB-CG2 4.33Å
603V92.4Very high90Very high0 Ų048 Ų480%023%0.227CC..Hα-helixtrans-61.6-49.6176.3168.10000111.4F599 Q600 L601 F605 A606 W607 T624 L626 L631 T634 L635 L638 L649F599-V603 WeakPolarHBondContact O-CG2 3.45Å; F599-V603 PolarHBondContact O-N 3.18Å; Q600-V603 PolarHBondContact O-N 3.07Å; L601-V603 VanDerWaalsContact C-N 3.34Å; L601-V603 PolarHBondContact O-N 3.41Å; V603-F605 VanDerWaalsContact C-N 3.26Å; V603-F605 PolarHBondContact O-N 2.89Å; V603-A606 VanDerWaalsContact O-CB 3.24Å; V603-A606 WeakPolarHBondContact O-CB 3.34Å; V603-A606 PolarHBondContact O-N 3.34Å; V603-W607 HydrophobicContact CG1-CH2 4.34Å; V603-W607 HydrophobicContact CG1-CZ3 3.81Å; V603-W607 VanDerWaalsContact O-CE3 3.25Å; V603-W607 WeakPolarHBondContact O-CZ3 3.37Å; V603-T624 HydrophobicContact CG2-CG2 4Å; V603-L626 HydrophobicContact CG2-CD1 4.19Å; V603-L631 HydrophobicContact CG2-CD1 3.73Å; V603-T634 HydrophobicContact CB-CG2 4.5Å; V603-T634 HydrophobicContact CG2-CG2 3.91Å; V603-L635 HydrophobicContact CG1-CD2 3.67Å; V603-L638 HydrophobicContact CB-CD1 4.41Å; V603-L638 HydrophobicContact CG1-CD1 3.85Å; V603-L649 HydrophobicContact CG1-CD1 4.43Å
604L91.7Very high90Very high18 Ų1850.5 Ų50.59%0.09424%0.236CC..Hα-helixtrans-65.9-30.1-178-70.8172.6000112.6I583 L594 V596 Q600 L601 A606 W607 L638 V648 L649I583-L604 HydrophobicContact CD1-CB 4.28Å; I583-L604 HydrophobicContact CD1-CD1 3.57Å; L594-L604 HydrophobicContact CD1-CD1 4.48Å; V596-L604 HydrophobicContact CG1-CD1 4.3Å; Q600-L604 WeakPolarHBondContact O-CB 3.39Å; Q600-L604 VanDerWaalsContact O-CG 3.28Å; Q600-L604 WeakPolarHBondContact O-CG 3.5Å; Q600-L604 PolarHBondContact O-N 2.96Å; L601-L604 PolarHBondContact O-N 3.06Å; L604-A606 PolarHBondContact O-N 2.72Å; L604-W607 PolarHBondContact O-N 3.13Å; L604-L638 HydrophobicContact CD1-CD2 4.16Å; L604-L638 HydrophobicContact CD2-CD1 4.16Å; L604-L638 HydrophobicContact CG-CD1 4.15Å; L604-L638 HydrophobicContact CG-CD2 4.48Å; L604-V648 HydrophobicContact CD2-CG1 4.07Å; L604-L649 HydrophobicContact CD2-CD1 4.38Å; L604-L649 HydrophobicContact CD2-CD2 4.01Å; L604-L649 HydrophobicContact CD2-CG 4.24Å
605F89.8Confident90.1Very high64 Ų6450.7 Ų50.728%0.28124%0.236SC..Hα-helixtrans-65.4-22.9177.8-160-103.3000113.1P549 E551 L601 A602 V603 W607 N608P549-F605 HydrophobicContact CB-CD1 3.92Å; P549-F605 HydrophobicContact CB-CD2 3.73Å; P549-F605 HydrophobicContact CB-CE1 3.92Å; P549-F605 HydrophobicContact CB-CE2 3.71Å; P549-F605 HydrophobicContact CB-CG 3.82Å; P549-F605 HydrophobicContact CB-CZ 3.81Å; P549-F605 HydrophobicContact CG-CB 3.81Å; P549-F605 HydrophobicContact CG-CD1 4.02Å; P549-F605 HydrophobicContact CG-CD2 3.77Å; P549-F605 HydrophobicContact CG-CE2 4.28Å; P549-F605 HydrophobicContact CG-CG 3.6Å; E551-F605 WeakPolarHBondContact OE2-CE2 3.41Å; E551-F605 WeakPolarHBondContact OE2-CZ 3.29Å; L601-F605 WeakPolarHBondContact O-CB 3.43Å; L601-F605 PolarHBondContact O-N 2.92Å; A602-F605 PolarHBondContact O-N 3.11Å; V603-F605 VanDerWaalsContact C-N 3.26Å; V603-F605 PolarHBondContact O-N 2.89Å; F605-W607 PolarHBondContact O-N 2.83Å; F605-N608 HydrophobicContact CD2-CB 4.06Å; F605-N608 HydrophobicContact CE2-CB 4.18Å; F605-N608 WeakPolarHBondContact CE2-ND2 3.24Å; F605-N608 HydrophobicContact CG-CB 4.38Å; F605-N608 WeakPolarHBondContact O-CB 3.5Å; F605-N608 PolarHBondContact O-N 2.94Å
606A90.3Very high90.2Very high17 Ų1749.2 Ų49.214%0.1423%0.231CC..THydrogen-bonded Turntrans-56.9-22.6174.100000113.2V603 L604 R610 I615 L620V603-A606 VanDerWaalsContact O-CB 3.24Å; V603-A606 WeakPolarHBondContact O-CB 3.34Å; V603-A606 PolarHBondContact O-N 3.34Å; L604-A606 PolarHBondContact O-N 2.72Å; A606-R610 WeakPolarHBondContact O-CG 3.29Å; A606-R610 PolarHBondContact O-NE 2.83Å; A606-I615 HydrophobicContact CB-CD1 4.04Å; A606-L620 HydrophobicContact CB-CD2 3.75Å
607W91.8Very high90.3Very high6 Ų649.2 Ų49.22%0.02323%0.231CC..THydrogen-bonded Turntrans-101.61.3177.6-68.4-84.5000115V603 L604 F605 Q609 R610 E613 I615 L620 L649 F667 V669V603-W607 HydrophobicContact CG1-CH2 4.34Å; V603-W607 HydrophobicContact CG1-CZ3 3.81Å; V603-W607 VanDerWaalsContact O-CE3 3.25Å; V603-W607 WeakPolarHBondContact O-CZ3 3.37Å; L604-W607 PolarHBondContact O-N 3.13Å; F605-W607 PolarHBondContact O-N 2.83Å; W607-Q609 VanDerWaalsContact C-N 3.33Å; W607-Q609 PolarHBondContact O-N 3.14Å; W607-R610 CarbonylContact O-C 3.22Å; W607-R610 PolarHBondContact O-N 3.21Å; W607-E613 PolarHBondContact NE1-O 3.44Å; W607-E613 VanDerWaalsContact NE1-O 3.12Å; W607-I615 HydrophobicContact CD2-CD1 3.99Å; W607-I615 HydrophobicContact CG-CD1 4.12Å; W607-I615 HydrophobicContact CZ2-CB 4.09Å; W607-I615 HydrophobicContact CZ2-CD1 4.03Å; W607-I615 HydrophobicContact CZ2-CG1 4.2Å; W607-L620 HydrophobicContact CH2-CD1 3.7Å; W607-L620 HydrophobicContact CH2-CD2 3.62Å; W607-L620 HydrophobicContact CH2-CG 4.3Å; W607-L620 HydrophobicContact CZ2-CD1 4.14Å; W607-L620 HydrophobicContact CZ2-CD2 4.07Å; W607-L620 HydrophobicContact CZ3-CD2 4.02Å; W607-L649 HydrophobicContact CE3-CD2 4.38Å; W607-L649 HydrophobicContact CH2-CD1 3.91Å; W607-L649 HydrophobicContact CH2-CD2 4.29Å; W607-L649 HydrophobicContact CZ3-CD1 3.94Å; W607-L649 HydrophobicContact CZ3-CD2 4.14Å; W607-F667 HydrophobicContact CH2-CB 4.02Å; W607-F667 HydrophobicContact CZ2-CB 3.82Å; W607-F667 WeakPolarHBondContact CZ2-O 3.3Å; W607-V669 HydrophobicContact CB-CG2 3.57Å; W607-V669 HydrophobicContact CD2-CG2 3.91Å; W607-V669 HydrophobicContact CE3-CG2 4.47Å; W607-V669 HydrophobicContact CG-CG2 3.5Å; W607-V669 VanDerWaalsContact CG-CG2 3.5Å
608N87.9Confident90.4Very high95 Ų9554 Ų5451%0.50825%0.253SS..THydrogen-bonded Turntrans-59.5-41.9-173.2-165.827.2000112.7F605F605-N608 HydrophobicContact CD2-CB 4.06Å; F605-N608 HydrophobicContact CE2-CB 4.18Å; F605-N608 WeakPolarHBondContact CE2-ND2 3.24Å; F605-N608 HydrophobicContact CG-CB 4.38Å; F605-N608 WeakPolarHBondContact O-CB 3.5Å; F605-N608 PolarHBondContact O-N 2.94Å
609Q85.7Confident90.6Very high190 Ų19057.5 Ų57.589%0.88827%0.272SS*.THydrogen-bonded Turntrans-91.6-7.8177-63.1178.91.400113.5W607W607-Q609 VanDerWaalsContact C-N 3.33Å; W607-Q609 PolarHBondContact O-N 3.14Å
610R88.5Confident90.6Very high96 Ų9657.3 Ų57.336%0.36227%0.271SS..  trans-140.166.2-174.553.3176.1165.3-171.8-3.5113.1A606 W607 R612 E613A606-R610 WeakPolarHBondContact O-CG 3.29Å; A606-R610 PolarHBondContact O-NE 2.83Å; W607-R610 CarbonylContact O-C 3.22Å; W607-R610 PolarHBondContact O-N 3.21Å; R610-R612 PolarHBondContact O-N 3.14Å; R610-R612 VanDerWaalsContact O-N 3.08Å; R610-E613 HydrophobicContact CB-CB 4.11Å; R610-E613 HydrophobicContact CB-CG 3.94Å; R610-E613 WeakPolarHBondContact CD-OE2 3.14Å; R610-E613 HydrophobicContact CG-CB 4.43Å; R610-E613 IonicContact NH1-OE2 3.73Å; R610-E613 PolarHBondContact O-N 3.27Å
611P83.5Confident90.7Very high67 Ų6760.9 Ų60.944%0.43529%0.286SS..THydrogen-bonded Turntrans-66.9-16.4-168.8-2335.3000115.9Q671P611-Q671 PolarHBondContact O-NE2 3.27Å
612R87.1Confident90.7Very high196 Ų19665.7 Ų65.774%0.7431%0.312SS*.THydrogen-bonded Turntrans-110.3-0.8-176.6-67.4-176.6173.8179-2.8113.9E588 R610E588-R612 IonicContact OE1-CZ 2.89Å; E588-R612 IonicContact OE1-NE 2.65Å; E588-R612 IonicContact OE1-NH2 3.14Å; E588-R612 PolarHBondContact OE1-NH2 2.63Å; R610-R612 PolarHBondContact O-N 3.14Å; R610-R612 VanDerWaalsContact O-N 3.08Å
613E91.4Very high90.6Very high103 Ų10367.8 Ų67.848%0.48133%0.328SS..  trans-81.7148.4-178.7-72.7-173.1-171.600112.6W607 R610W607-E613 PolarHBondContact NE1-O 3.44Å; W607-E613 VanDerWaalsContact NE1-O 3.12Å; R610-E613 HydrophobicContact CB-CB 4.11Å; R610-E613 HydrophobicContact CB-CG 3.94Å; R610-E613 WeakPolarHBondContact CD-OE2 3.14Å; R610-E613 HydrophobicContact CG-CB 4.43Å; R610-E613 IonicContact NH1-OE2 3.73Å; R610-E613 PolarHBondContact O-N 3.27Å
614K92.1Very high90.5Very high114 Ų11467.9 Ų67.950%0.49633%0.329SS..  trans-93.9125.5170.3-60.6-171.2176.2-175.50108.9L666 F667 Y668K614-L666 HydrophobicContact CB-CB 4.3Å; K614-L666 HydrophobicContact CB-CD1 4.44Å; K614-L666 HydrophobicContact CD-CD1 4.21Å; K614-F667 CarbonylContact C-O 3.59Å; K614-F667 WeakPolarHBondContact CA-O 3.18Å; K614-Y668 HydrophobicContact CD-CD1 4.12Å; K614-Y668 HydrophobicContact CG-CD1 3.92Å; K614-Y668 HydrophobicContact CG-CG 4.14Å
615I93.3Very high90.4Very high3 Ų373 Ų732%0.01535%0.352CS..EExtended strand (participates in β ladder)trans-115.1131-178.9-50.6178000108.5A606 W607 N619 L620 F667A606-I615 HydrophobicContact CB-CD1 4.04Å; W607-I615 HydrophobicContact CD2-CD1 3.99Å; W607-I615 HydrophobicContact CG-CD1 4.12Å; W607-I615 HydrophobicContact CZ2-CB 4.09Å; W607-I615 HydrophobicContact CZ2-CD1 4.03Å; W607-I615 HydrophobicContact CZ2-CG1 4.2Å; I615-N619 HydrophobicContact CG2-CB 3.63Å; I615-L620 HydrophobicContact CB-CD2 4.19Å; I615-L620 HydrophobicContact CB-CG 4.18Å; I615-L620 HydrophobicContact CD1-CD2 4.27Å; I615-L620 HydrophobicContact CG2-CD2 3.82Å; I615-L620 HydrophobicContact CG2-CG 3.69Å; I615-F667 PolarHBondContact N-O 3.43Å; I615-F667 PolarHBondContact O-N 3.42Å
616S94.2Very high90.4Very high16 Ų1670 Ų7011%0.11234%0.34CS..EExtended strand (participates in β ladder)trans-70.8158.6176.663.30000112.3E618 N619 L620 T665S616-E618 VanDerWaalsContact C-N 3.28Å; S616-E618 PolarHBondContact O-N 3.42Å; S616-N619 PolarHBondContact O-N 3.44Å; S616-N619 WeakPolarHBondContact OG-CB 3.37Å; S616-N619 VanDerWaalsContact OG-CG 3.25Å; S616-N619 PolarHBondContact OG-N 3Å; S616-N619 PolarHBondContact OG-ND2 3.05Å; S616-L620 WeakPolarHBondContact O-CG 3.31Å; S616-L620 PolarHBondContact O-N 3.35Å; S616-T665 CarbonylContact C-O 3.42Å; S616-T665 WeakPolarHBondContact CA-O 3.41Å
617F93.1Very high90.3Very high0 Ų071.7 Ų71.70%035%0.349CS..Hα-helixtrans-54.9-44.1173.5-177.4-96.7000112N619 L620 K621 L631 R632 L635 F661 T662 D663 T665 F667F617-N619 PolarHBondContact O-N 3.29Å; F617-L620 PolarHBondContact O-N 3.38Å; F617-K621 HydrophobicContact CE1-CD 4.39Å; F617-K621 WeakPolarHBondContact O-CB 3.26Å; F617-K621 PolarHBondContact O-N 3.26Å; F617-L631 HydrophobicContact CD2-CD2 4.26Å; F617-L631 HydrophobicContact CE1-CD2 4.4Å; F617-L631 HydrophobicContact CE2-CB 4.42Å; F617-L631 HydrophobicContact CE2-CD2 3.74Å; F617-L631 HydrophobicContact CE2-CG 3.82Å; F617-L631 HydrophobicContact CZ-CB 4.44Å; F617-L631 HydrophobicContact CZ-CD2 3.82Å; F617-L631 HydrophobicContact CZ-CG 4.17Å; F617-R632 HydrophobicContact CE2-CG 3.65Å; F617-R632 HydrophobicContact CZ-CG 3.63Å; F617-L635 HydrophobicContact CD2-CD1 3.62Å; F617-L635 HydrophobicContact CE2-CD1 3.79Å; F617-F661 HydrophobicContact CD2-CB 4.46Å; F617-T662 VanDerWaalsContact CB-O 3.3Å; F617-T662 WeakPolarHBondContact CB-O 3.34Å; F617-D663 PolarHBondContact N-O 2.81Å; F617-T665 PolarHBondContact N-O 3.04Å; F617-F667 HydrophobicContact CB-CE2 4.06Å; F617-F667 HydrophobicContact CD2-CE2 4.15Å
618E93.3Very high90.1Very high108 Ų10873.9 Ų73.951%0.50536%0.361SS..Hα-helixtrans-59-46.8177.1-175.6179.2-167.300112.1S616 L620 K621 L622 D663S616-E618 VanDerWaalsContact C-N 3.28Å; S616-E618 PolarHBondContact O-N 3.42Å; E618-L620 VanDerWaalsContact C-N 3.33Å; E618-L620 PolarHBondContact O-N 2.88Å; E618-K621 WeakPolarHBondContact O-CB 3.29Å; E618-K621 PolarHBondContact O-N 3.2Å; E618-L622 WeakPolarHBondContact O-CG 3.48Å; E618-L622 PolarHBondContact O-N 3Å; E618-D663 HydrophobicContact CB-CB 4.31Å; E618-D663 PolarHBondContact N-O 3.37Å
619N92.4Very high90Very high83 Ų8372.4 Ų72.444%0.44436%0.362SS..Hα-helixtrans-66.7-35.5179.6-73.8-18.4000112I615 S616 F617 L622 A623I615-N619 HydrophobicContact CG2-CB 3.63Å; S616-N619 PolarHBondContact O-N 3.44Å; S616-N619 WeakPolarHBondContact OG-CB 3.37Å; S616-N619 VanDerWaalsContact OG-CG 3.25Å; S616-N619 PolarHBondContact OG-N 3Å; S616-N619 PolarHBondContact OG-ND2 3.05Å; F617-N619 PolarHBondContact O-N 3.29Å; N619-L622 PolarHBondContact O-N 2.92Å; N619-A623 VanDerWaalsContact O-CB 3.25Å; N619-A623 WeakPolarHBondContact O-CB 3.41Å; N619-A623 PolarHBondContact O-N 3.38Å
620L92.1Very high89.9Confident0 Ų064.6 Ų64.60%033%0.326CS..Hα-helixtrans-67.6-37173.5-70.8169.9000111.9A606 W607 I615 S616 F617 E618 A623 T624 L635 F667A606-L620 HydrophobicContact CB-CD2 3.75Å; W607-L620 HydrophobicContact CH2-CD1 3.7Å; W607-L620 HydrophobicContact CH2-CD2 3.62Å; W607-L620 HydrophobicContact CH2-CG 4.3Å; W607-L620 HydrophobicContact CZ2-CD1 4.14Å; W607-L620 HydrophobicContact CZ2-CD2 4.07Å; W607-L620 HydrophobicContact CZ3-CD2 4.02Å; I615-L620 HydrophobicContact CB-CD2 4.19Å; I615-L620 HydrophobicContact CB-CG 4.18Å; I615-L620 HydrophobicContact CD1-CD2 4.27Å; I615-L620 HydrophobicContact CG2-CD2 3.82Å; I615-L620 HydrophobicContact CG2-CG 3.69Å; S616-L620 WeakPolarHBondContact O-CG 3.31Å; S616-L620 PolarHBondContact O-N 3.35Å; F617-L620 PolarHBondContact O-N 3.38Å; E618-L620 VanDerWaalsContact C-N 3.33Å; E618-L620 PolarHBondContact O-N 2.88Å; L620-A623 PolarHBondContact O-N 3.1Å; L620-T624 WeakPolarHBondContact O-CB 3.43Å; L620-T624 WeakPolarHBondContact O-CG2 3.38Å; L620-T624 PolarHBondContact O-N 3.1Å; L620-T624 PolarHBondContact O-OG1 3.36Å; L620-L635 HydrophobicContact CD1-CD1 4.36Å; L620-L635 HydrophobicContact CD1-CD2 4.02Å; L620-F667 HydrophobicContact CD1-CB 4Å; L620-F667 HydrophobicContact CD1-CD2 3.81Å; L620-F667 HydrophobicContact CD1-CG 4.1Å
621K91.8Very high90Very high76 Ų7660 Ų6033%0.3331%0.308SS..Hα-helixtrans-63.4-43.4175.1-172177.4-180173.90111.7F617 E618 E625 D628 L631F617-K621 HydrophobicContact CE1-CD 4.39Å; F617-K621 WeakPolarHBondContact O-CB 3.26Å; F617-K621 PolarHBondContact O-N 3.26Å; E618-K621 WeakPolarHBondContact O-CB 3.29Å; E618-K621 PolarHBondContact O-N 3.2Å; K621-E625 WeakPolarHBondContact O-CA 3.36Å; K621-E625 PolarHBondContact O-N 3.23Å; K621-D628 IonicContact NZ-OD1 2.69Å; K621-D628 PolarHBondContact NZ-OD1 3.18Å; K621-L631 HydrophobicContact CB-CD2 3.61Å; K621-L631 HydrophobicContact CG-CD2 4.15Å
622L91.1Very high90.3Very high122 Ų12258.6 Ų58.664%0.63929%0.294SS*.Hα-helixtrans-66.4-43.2174.5-67.3173.5000112.1E618 N619 T624E618-L622 WeakPolarHBondContact O-CG 3.48Å; E618-L622 PolarHBondContact O-N 3Å; N619-L622 PolarHBondContact O-N 2.92Å; L622-T624 VanDerWaalsContact C-N 3.35Å; L622-T624 PolarHBondContact O-N 2.89Å
623A88.9Confident90.3Very high49 Ų4951.9 Ų51.941%0.40527%0.269SS..Hα-helixtrans-70.8-28.5-176.900000113.9N619 L620N619-A623 VanDerWaalsContact O-CB 3.25Å; N619-A623 WeakPolarHBondContact O-CB 3.41Å; N619-A623 PolarHBondContact O-N 3.38Å; L620-A623 PolarHBondContact O-N 3.1Å
624T89.8Confident90.2Very high2 Ų247.1 Ų47.11%0.01225%0.247CC..Hα-helixtrans-104.1-14.2-177.660.80000113.7V546 S547 A602 V603 L620 L622 L626V546-T624 WeakPolarHBondContact CA-O 3.15Å; S547-T624 PolarHBondContact N-O 3.22Å; A602-T624 HydrophobicContact CB-CG2 4.33Å; V603-T624 HydrophobicContact CG2-CG2 4Å; L620-T624 WeakPolarHBondContact O-CB 3.43Å; L620-T624 WeakPolarHBondContact O-CG2 3.38Å; L620-T624 PolarHBondContact O-N 3.1Å; L620-T624 PolarHBondContact O-OG1 3.36Å; L622-T624 VanDerWaalsContact C-N 3.35Å; L622-T624 PolarHBondContact O-N 2.89Å; T624-L626 PolarHBondContact O-N 2.87Å
625E90.7Very high90.1Very high125 Ų12541.7 Ų41.758%0.58422%0.223SC*.  trans54.716.8-172.8-63.6-176.1164.600114.7S547 K621S547-E625 WeakPolarHBondContact OG-CG 2.99Å; K621-E625 WeakPolarHBondContact O-CA 3.36Å; K621-E625 PolarHBondContact O-N 3.23Å
626L88.9Confident89.9Confident3 Ų344.7 Ų44.72%0.01624%0.235CC..  trans-73.5142.4-177.7-74.1172.6000111.7V544 V546 F599 V603 T624 L631V544-L626 HydrophobicContact CG1-CD2 4.01Å; V546-L626 HydrophobicContact CB-CD2 3.84Å; V546-L626 HydrophobicContact CG2-CD2 3.83Å; V546-L626 HydrophobicContact CG2-CG 4.14Å; F599-L626 HydrophobicContact CB-CD1 4.05Å; F599-L626 HydrophobicContact CB-CD2 4.42Å; F599-L626 HydrophobicContact CD1-CD2 3.72Å; F599-L626 HydrophobicContact CD2-CD2 4.2Å; F599-L626 HydrophobicContact CE1-CD2 3.95Å; F599-L626 HydrophobicContact CE2-CD2 4.39Å; F599-L626 HydrophobicContact CG-CD1 4.39Å; F599-L626 HydrophobicContact CG-CD2 3.87Å; F599-L626 HydrophobicContact CZ-CD2 4.29Å; V603-L626 HydrophobicContact CG2-CD1 4.19Å; T624-L626 PolarHBondContact O-N 2.87Å; L626-L631 HydrophobicContact CB-CB 4.06Å; L626-L631 HydrophobicContact CD1-CD1 4.2Å
627P88.8Confident89.6Confident52 Ų5244.5 Ų44.534%0.33823%0.233SC..  trans-58.2145.2169.7-23.333.3000111.5V544 A629 E630 L631V544-P627 HydrophobicContact CG1-CG 3.98Å; P627-A629 VanDerWaalsContact C-N 3.31Å; P627-A629 PolarHBondContact O-N 3.26Å; P627-E630 PolarHBondContact O-N 2.81Å; P627-L631 PolarHBondContact O-N 3.31Å
628D87.7Confident89.4Confident52 Ų5244.6 Ų44.628%0.27823%0.233SC..Hα-helixtrans-51-47.7-174.2-160.7113.1000113.3K621 E630 L631 R632K621-D628 IonicContact NZ-OD1 2.69Å; K621-D628 PolarHBondContact NZ-OD1 3.18Å; D628-E630 PolarHBondContact O-N 2.72Å; D628-L631 PolarHBondContact O-N 3.14Å; D628-R632 VanDerWaalsContact O-CG 3.29Å; D628-R632 WeakPolarHBondContact O-CG 3.41Å; D628-R632 PolarHBondContact O-N 2.69Å; D628-R632 VanDerWaalsContact OD2-CD 3.31Å; D628-R632 WeakPolarHBondContact OD2-CD 3.34Å; D628-R632 IonicContact OD2-CZ 3.92Å; D628-R632 IonicContact OD2-NE 2.78Å; D628-R632 PolarHBondContact OD2-NE 3.49Å; D628-R632 IonicContact OD2-NH2 2.8Å
629A85.1Confident89.2Confident64 Ų6439.8 Ų39.853%0.52921%0.212SC..Hα-helixtrans-62.9-40.6179.100000113P627 R633P627-A629 VanDerWaalsContact C-N 3.31Å; P627-A629 PolarHBondContact O-N 3.26Å; A629-R633 WeakPolarHBondContact O-CB 3.29Å; A629-R633 PolarHBondContact O-N 2.86Å
630E84.9Confident88.8Confident25 Ų2537.2 Ų37.212%0.11720%0.202CC..Hα-helixtrans-74.3-39.3179.8-71.1-56.8147.200111.5P627 D628 R633 T634P627-E630 PolarHBondContact O-N 2.81Å; D628-E630 PolarHBondContact O-N 2.72Å; E630-R633 PolarHBondContact O-N 2.81Å; E630-R633 IonicContact OE1-NE 2.7Å; E630-R633 IonicContact OE1-NH2 3.71Å; E630-R633 IonicContact OE2-CZ 3.95Å; E630-R633 VanDerWaalsContact OE2-CZ 3.29Å; E630-R633 IonicContact OE2-NE 3.06Å; E630-R633 PolarHBondContact OE2-NE 2.91Å; E630-R633 VanDerWaalsContact OE2-NE 3.12Å; E630-R633 IonicContact OE2-NH2 3.57Å; E630-R633 PolarHBondContact OE2-NH2 3.35Å; E630-T634 VanDerWaalsContact O-CB 3.25Å; E630-T634 WeakPolarHBondContact O-CB 3.39Å; E630-T634 PolarHBondContact O-N 3.42Å; E630-T634 PolarHBondContact O-OG1 2.92Å
631L89.2Confident88.4Confident0 Ų038.4 Ų38.40%021%0.207CC..Hα-helixtrans-63.3-47176.6-179.460.8000111.5V603 F617 K621 L626 P627 D628 R633 T634 L635V603-L631 HydrophobicContact CG2-CD1 3.73Å; F617-L631 HydrophobicContact CD2-CD2 4.26Å; F617-L631 HydrophobicContact CE1-CD2 4.4Å; F617-L631 HydrophobicContact CE2-CB 4.42Å; F617-L631 HydrophobicContact CE2-CD2 3.74Å; F617-L631 HydrophobicContact CE2-CG 3.82Å; F617-L631 HydrophobicContact CZ-CB 4.44Å; F617-L631 HydrophobicContact CZ-CD2 3.82Å; F617-L631 HydrophobicContact CZ-CG 4.17Å; K621-L631 HydrophobicContact CB-CD2 3.61Å; K621-L631 HydrophobicContact CG-CD2 4.15Å; L626-L631 HydrophobicContact CB-CB 4.06Å; L626-L631 HydrophobicContact CD1-CD1 4.2Å; P627-L631 PolarHBondContact O-N 3.31Å; D628-L631 PolarHBondContact O-N 3.14Å; L631-R633 VanDerWaalsContact C-N 3.31Å; L631-R633 PolarHBondContact O-N 3.14Å; L631-T634 PolarHBondContact O-N 3.44Å; L631-L635 HydrophobicContact CD1-CD1 3.89Å; L631-L635 HydrophobicContact CD1-CG 4.05Å; L631-L635 HydrophobicContact CG-CD1 3.82Å; L631-L635 HydrophobicContact CG-CG 4.39Å; L631-L635 WeakPolarHBondContact O-CB 3.4Å; L631-L635 WeakPolarHBondContact O-CG 3.47Å; L631-L635 PolarHBondContact O-N 2.85Å
632R90.1Very high87.8Confident37 Ų3740.9 Ų40.914%0.1423%0.231CC..Hα-helixtrans-57.7-44.5176.5-72.6172.2-177.7-82.4-11112.1F617 D628 W636 P658 K659 F661F617-R632 HydrophobicContact CE2-CG 3.65Å; F617-R632 HydrophobicContact CZ-CG 3.63Å; D628-R632 VanDerWaalsContact O-CG 3.29Å; D628-R632 WeakPolarHBondContact O-CG 3.41Å; D628-R632 PolarHBondContact O-N 2.69Å; D628-R632 VanDerWaalsContact OD2-CD 3.31Å; D628-R632 WeakPolarHBondContact OD2-CD 3.34Å; D628-R632 IonicContact OD2-CZ 3.92Å; D628-R632 IonicContact OD2-NE 2.78Å; D628-R632 PolarHBondContact OD2-NE 3.49Å; D628-R632 IonicContact OD2-NH2 2.8Å; R632-W636 VanDerWaalsContact O-CB 3.28Å; R632-W636 WeakPolarHBondContact O-CB 3.21Å; R632-W636 PolarHBondContact O-N 2.8Å; R632-P658 HydrophobicContact CB-CB 4.3Å; R632-P658 WeakPolarHBondContact CD-O 3.49Å; R632-P658 PolarHBondContact NH1-O 2.59Å; R632-K659 PolarHBondContact NH1-O 3.14Å; R632-F661 HydrophobicContact CB-CD2 4.4Å; R632-F661 HydrophobicContact CG-CD2 4.29Å; R632-F661 VanDerWaalsContact CZ-O 3.26Å; R632-F661 PolarHBondContact NH1-O 2.91Å; R632-F661 PolarHBondContact NH2-O 3.49Å
633R86.8Confident87.2Confident56 Ų5644.1 Ų44.121%0.21124%0.24CC..Hα-helixtrans-64.8-42.9178.5-170.9174.671.9123.93.9111.6A629 E630 L631 S637 L693 T697A629-R633 WeakPolarHBondContact O-CB 3.29Å; A629-R633 PolarHBondContact O-N 2.86Å; E630-R633 PolarHBondContact O-N 2.81Å; E630-R633 IonicContact OE1-NE 2.7Å; E630-R633 IonicContact OE1-NH2 3.71Å; E630-R633 IonicContact OE2-CZ 3.95Å; E630-R633 VanDerWaalsContact OE2-CZ 3.29Å; E630-R633 IonicContact OE2-NE 3.06Å; E630-R633 PolarHBondContact OE2-NE 2.91Å; E630-R633 VanDerWaalsContact OE2-NE 3.12Å; E630-R633 IonicContact OE2-NH2 3.57Å; E630-R633 PolarHBondContact OE2-NH2 3.35Å; L631-R633 VanDerWaalsContact C-N 3.31Å; L631-R633 PolarHBondContact O-N 3.14Å; R633-S637 PolarHBondContact O-N 2.84Å; R633-L693 HydrophobicContact CG-CD2 3.75Å; R633-L693 PolarHBondContact NH1-O 2.9Å; R633-L693 PolarHBondContact NH2-O 3.48Å; R633-T697 VanDerWaalsContact NH1-CG2 3.25Å
634T89.3Confident86.9Confident2 Ų243.1 Ų43.11%0.01223%0.228CC..Hα-helixtrans-63-49176.7-60.40000110.8F599 Q600 V603 E630 L631 W636 S637 L638F599-T634 HydrophobicContact CB-CG2 4.06Å; Q600-T634 HydrophobicContact CB-CG2 4.25Å; Q600-T634 HydrophobicContact CG-CG2 3.71Å; V603-T634 HydrophobicContact CB-CG2 4.5Å; V603-T634 HydrophobicContact CG2-CG2 3.91Å; E630-T634 VanDerWaalsContact O-CB 3.25Å; E630-T634 WeakPolarHBondContact O-CB 3.39Å; E630-T634 PolarHBondContact O-N 3.42Å; E630-T634 PolarHBondContact O-OG1 2.92Å; L631-T634 PolarHBondContact O-N 3.44Å; T634-W636 PolarHBondContact O-N 3.29Å; T634-S637 PolarHBondContact O-N 2.88Å; T634-S637 PolarHBondContact O-OG 3.33Å; T634-L638 PolarHBondContact O-N 3.1Å
635L90.1Very high86.5Confident0 Ų050.6 Ų50.60%026%0.26CS..Hα-helixtrans-62.7-44.3177.6-74168.2000112V603 F617 L620 L631 S637 L638 V639 L649 F661 F667V603-L635 HydrophobicContact CG1-CD2 3.67Å; F617-L635 HydrophobicContact CD2-CD1 3.62Å; F617-L635 HydrophobicContact CE2-CD1 3.79Å; L620-L635 HydrophobicContact CD1-CD1 4.36Å; L620-L635 HydrophobicContact CD1-CD2 4.02Å; L631-L635 HydrophobicContact CD1-CD1 3.89Å; L631-L635 HydrophobicContact CD1-CG 4.05Å; L631-L635 HydrophobicContact CG-CD1 3.82Å; L631-L635 HydrophobicContact CG-CG 4.39Å; L631-L635 WeakPolarHBondContact O-CB 3.4Å; L631-L635 WeakPolarHBondContact O-CG 3.47Å; L631-L635 PolarHBondContact O-N 2.85Å; L635-S637 PolarHBondContact O-N 2.94Å; L635-L638 WeakPolarHBondContact O-CA 3.25Å; L635-L638 WeakPolarHBondContact O-CB 3.43Å; L635-L638 PolarHBondContact O-N 3.05Å; L635-V639 WeakPolarHBondContact O-CG2 3.46Å; L635-V639 PolarHBondContact O-N 3.3Å; L635-L649 HydrophobicContact CD2-CD1 4.2Å; L635-F661 HydrophobicContact CB-CE2 4.27Å; L635-F667 HydrophobicContact CB-CE1 4.16Å; L635-F667 HydrophobicContact CB-CZ 4.42Å; L635-F667 HydrophobicContact CD1-CD2 4.41Å; L635-F667 HydrophobicContact CD1-CE1 4.25Å; L635-F667 HydrophobicContact CD1-CE2 3.95Å; L635-F667 HydrophobicContact CD1-CZ 3.87Å; L635-F667 HydrophobicContact CD2-CD1 4.09Å; L635-F667 HydrophobicContact CD2-CE1 4.27Å; L635-F667 HydrophobicContact CD2-CG 4.3Å; L635-F667 HydrophobicContact CG-CE1 4.48Å
636W89.9Confident86.2Confident67 Ų6747.7 Ų47.725%0.25425%0.245SC..Hα-helixtrans-55.5-39.7177.4-169.6-102.2000112.6R632 T634 L638 V639 A640 V655 S656 P658 F661R632-W636 VanDerWaalsContact O-CB 3.28Å; R632-W636 WeakPolarHBondContact O-CB 3.21Å; R632-W636 PolarHBondContact O-N 2.8Å; T634-W636 PolarHBondContact O-N 3.29Å; W636-L638 PolarHBondContact O-N 2.86Å; W636-V639 HydrophobicContact CE3-CG2 4.25Å; W636-V639 PolarHBondContact O-N 3.36Å; W636-A640 HydrophobicContact CD2-CB 3.96Å; W636-A640 HydrophobicContact CE3-CB 4.38Å; W636-A640 HydrophobicContact CG-CB 4.47Å; W636-A640 HydrophobicContact CH2-CB 4.1Å; W636-A640 HydrophobicContact CZ2-CB 3.69Å; W636-A640 HydrophobicContact CZ3-CB 4.43Å; W636-A640 WeakPolarHBondContact O-CA 3.44Å; W636-A640 PolarHBondContact O-N 3.07Å; W636-V655 HydrophobicContact CZ3-CG2 4.23Å; W636-S656 WeakPolarHBondContact CH2-O 3.43Å; W636-S656 WeakPolarHBondContact CZ2-O 3.43Å; W636-P658 HydrophobicContact CB-CB 3.93Å; W636-P658 HydrophobicContact CD2-CB 4.17Å; W636-P658 HydrophobicContact CD2-CG 4.31Å; W636-P658 HydrophobicContact CE3-CB 4.24Å; W636-P658 HydrophobicContact CG-CB 4.03Å; W636-P658 HydrophobicContact CG-CG 4.22Å; W636-F661 HydrophobicContact CB-CE2 4.43Å; W636-F661 HydrophobicContact CE3-CE1 4.4Å; W636-F661 AromaticContact CE3-CE2 3.93Å; W636-F661 HydrophobicContact CE3-CE2 3.93Å; W636-F661 AromaticContact CE3-CZ 3.56Å; W636-F661 HydrophobicContact CE3-CZ 3.56Å; W636-F661 HydrophobicContact CZ3-CE1 4.49Å; W636-F661 HydrophobicContact CZ3-CZ 4.06Å
637S87.5Confident86.3Confident12 Ų1249.4 Ų49.48%0.08425%0.253CS..Hα-helixtrans-66.2-23.2177.176.60000114.6Q600 R633 T634 L635 L693Q600-S637 PolarHBondContact NE2-OG 2.84Å; R633-S637 PolarHBondContact O-N 2.84Å; T634-S637 PolarHBondContact O-N 2.88Å; T634-S637 PolarHBondContact O-OG 3.33Å; L635-S637 PolarHBondContact O-N 2.94Å; S637-L693 VanDerWaalsContact CB-CD1 3.48Å; S637-L693 VanDerWaalsContact OG-CD1 3.28Å; S637-L693 WeakPolarHBondContact OG-CD1 3.37Å
638L88.8Confident86.3Confident1 Ų147 Ų471%0.00524%0.237CC..Hα-helixtrans-91.3-27.6179.8-64.8172.7000112.1Q600 V603 L604 T634 L635 W636 V648 L649 L689Q600-L638 HydrophobicContact CB-CD2 4.37Å; Q600-L638 HydrophobicContact CG-CD1 4.42Å; Q600-L638 HydrophobicContact CG-CD2 4.14Å; Q600-L638 HydrophobicContact CG-CG 4.25Å; V603-L638 HydrophobicContact CB-CD1 4.41Å; V603-L638 HydrophobicContact CG1-CD1 3.85Å; L604-L638 HydrophobicContact CD1-CD2 4.16Å; L604-L638 HydrophobicContact CD2-CD1 4.16Å; L604-L638 HydrophobicContact CG-CD1 4.15Å; L604-L638 HydrophobicContact CG-CD2 4.48Å; T634-L638 PolarHBondContact O-N 3.1Å; L635-L638 WeakPolarHBondContact O-CA 3.25Å; L635-L638 WeakPolarHBondContact O-CB 3.43Å; L635-L638 PolarHBondContact O-N 3.05Å; W636-L638 PolarHBondContact O-N 2.86Å; L638-V648 PolarHBondContact O-N 3Å; L638-L649 HydrophobicContact CB-CB 4.32Å; L638-L649 HydrophobicContact CB-CD1 3.77Å; L638-L649 HydrophobicContact CB-CG 3.97Å; L638-L649 HydrophobicContact CD1-CD1 3.73Å; L638-L649 HydrophobicContact CD1-CG 4.49Å; L638-L649 HydrophobicContact CG-CD1 4.39Å; L638-L649 PolarHBondContact O-N 3.22Å; L638-L649 VanDerWaalsContact O-N 3.14Å; L638-L689 HydrophobicContact CD2-CD1 4.27Å
639V89.2Confident86.5Confident8 Ų844.6 Ų44.65%0.04823%0.225CC..Hα-helixtrans-99.5-19.3-179.9-58.70000114.7L635 W636 Q647 L649 Y651 F661 F667L635-V639 WeakPolarHBondContact O-CG2 3.46Å; L635-V639 PolarHBondContact O-N 3.3Å; W636-V639 HydrophobicContact CE3-CG2 4.25Å; W636-V639 PolarHBondContact O-N 3.36Å; V639-Q647 WeakPolarHBondContact O-CB 3.11Å; V639-Q647 WeakPolarHBondContact O-CG 3.38Å; V639-L649 HydrophobicContact CG1-CB 3.62Å; V639-Y651 HydrophobicContact CB-CD1 3.52Å; V639-Y651 HydrophobicContact CB-CE1 3.73Å; V639-Y651 HydrophobicContact CG1-CD1 3.61Å; V639-Y651 HydrophobicContact CG1-CE1 4.33Å; V639-Y651 HydrophobicContact CG1-CG 4.29Å; V639-Y651 HydrophobicContact CG2-CD1 3.87Å; V639-Y651 HydrophobicContact CG2-CE1 3.79Å; V639-F661 HydrophobicContact CG2-CZ 3.97Å; V639-F667 HydrophobicContact CG1-CD1 3.96Å; V639-F667 HydrophobicContact CG1-CE1 4.08Å
640A84.9Confident86.8Confident29 Ų2942.9 Ų42.924%0.2421%0.209CC..  trans-143.647.9-172.100000111.9W636 P642W636-A640 HydrophobicContact CD2-CB 3.96Å; W636-A640 HydrophobicContact CE3-CB 4.38Å; W636-A640 HydrophobicContact CG-CB 4.47Å; W636-A640 HydrophobicContact CH2-CB 4.1Å; W636-A640 HydrophobicContact CZ2-CB 3.69Å; W636-A640 HydrophobicContact CZ3-CB 4.43Å; W636-A640 WeakPolarHBondContact O-CA 3.44Å; W636-A640 PolarHBondContact O-N 3.07Å; A640-P642 WeakPolarHBondContact O-CD 3.42Å
641F83.8Confident87.1Confident25 Ų2544 Ų4411%0.1121%0.212CC..  trans-74.1120.1176.5-164.4-97.7000111.3K643 L644 Q647 N688 L689F641-K643 VanDerWaalsContact C-N 3.29Å; F641-K643 HydrophobicContact CD1-CB 4.11Å; F641-K643 HydrophobicContact CE1-CB 3.83Å; F641-K643 HydrophobicContact CE1-CG 4.34Å; F641-K643 PolarHBondContact O-N 3.13Å; F641-K643 VanDerWaalsContact O-N 3.12Å; F641-L644 HydrophobicContact CB-CB 4.39Å; F641-L644 HydrophobicContact CB-CD1 4.07Å; F641-L644 HydrophobicContact CB-CG 4.42Å; F641-L644 HydrophobicContact CD1-CB 4.25Å; F641-L644 HydrophobicContact CD1-CD1 3.89Å; F641-L644 HydrophobicContact CD1-CG 3.7Å; F641-L644 HydrophobicContact CE1-CG 4.42Å; F641-L644 HydrophobicContact CG-CD1 4.21Å; F641-L644 HydrophobicContact CG-CG 4.44Å; F641-L644 PolarHBondContact O-N 3.44Å; F641-L644 VanDerWaalsContact O-N 3.16Å; F641-Q647 PolarHBondContact O-NE2 2.67Å; F641-N688 WeakPolarHBondContact CZ-O 3.43Å; F641-L689 HydrophobicContact CD1-CD2 4.37Å; F641-L689 HydrophobicContact CD2-CD2 4.13Å; F641-L689 HydrophobicContact CE2-CD2 4.38Å; F641-L689 HydrophobicContact CG-CD2 4.12Å
642P77.9Confident87.1Confident127 Ų12748 Ų4883%0.82523%0.234SC*.THydrogen-bonded Turntrans-62-27.2-168.8-27.635.2000116.1A640A640-P642 WeakPolarHBondContact O-CD 3.42Å
643K78.8Confident86.9Confident191 Ų19149.6 Ų49.683%0.8325%0.249SC*.THydrogen-bonded Turntrans-92.2-1.8-176.6-60-178.6175.8178.80113.6F641F641-K643 VanDerWaalsContact C-N 3.29Å; F641-K643 HydrophobicContact CD1-CB 4.11Å; F641-K643 HydrophobicContact CE1-CB 3.83Å; F641-K643 HydrophobicContact CE1-CG 4.34Å; F641-K643 PolarHBondContact O-N 3.13Å; F641-K643 VanDerWaalsContact O-N 3.12Å
644L82.4Confident86.6Confident28 Ų2852 Ų5215%0.14727%0.274CS..  trans-107.2130.8-177.5-72.1176.2000111F641 Q647 F673 I687 L689F641-L644 HydrophobicContact CB-CB 4.39Å; F641-L644 HydrophobicContact CB-CD1 4.07Å; F641-L644 HydrophobicContact CB-CG 4.42Å; F641-L644 HydrophobicContact CD1-CB 4.25Å; F641-L644 HydrophobicContact CD1-CD1 3.89Å; F641-L644 HydrophobicContact CD1-CG 3.7Å; F641-L644 HydrophobicContact CE1-CG 4.42Å; F641-L644 HydrophobicContact CG-CD1 4.21Å; F641-L644 HydrophobicContact CG-CG 4.44Å; F641-L644 PolarHBondContact O-N 3.44Å; F641-L644 VanDerWaalsContact O-N 3.16Å; L644-Q647 PolarHBondContact O-NE2 3.35Å; L644-F673 HydrophobicContact CD1-CE2 4.3Å; L644-I687 HydrophobicContact CD1-CG2 4.24Å; L644-I687 HydrophobicContact CD2-CD1 4.34Å; L644-I687 HydrophobicContact CD2-CG2 4.21Å; L644-L689 HydrophobicContact CD1-CD2 3.52Å
645K82.2Confident86.3Confident159 Ų15953 Ų5369%0.69128%0.28SS*.SBendtrans-75.1-35.9174.3-69.8-172.3176-172.20112.3I676K645-I676 HydrophobicContact CB-CD1 4.01Å; K645-I676 HydrophobicContact CD-CB 4.27Å; K645-I676 HydrophobicContact CD-CD1 4Å; K645-I676 HydrophobicContact CD-CG2 4.26Å
646K84.9Confident85.8Confident64 Ų6458.4 Ų58.428%0.27832%0.318SS..SBendtrans-117.4131.3173.4-68.6-165173.6-163.70108.5E672 F673K646-E672 WeakPolarHBondContact CD-O 3.43Å; K646-E672 PolarHBondContact NZ-O 2.93Å; K646-E672 IonicContact NZ-OE2 3.29Å; K646-F673 HydrophobicContact CB-CD2 4.33Å; K646-F673 WeakPolarHBondContact O-CD2 3.28Å; K646-F673 WeakPolarHBondContact O-CE2 3.39Å
647Q90.1Very high85.3Confident39 Ų3956.9 Ų56.918%0.18232%0.317CS..  trans-90.7154.9-173.6-56.4-66.4-18.800110.6V639 F641 L644 N670 F673V639-Q647 WeakPolarHBondContact O-CB 3.11Å; V639-Q647 WeakPolarHBondContact O-CG 3.38Å; F641-Q647 PolarHBondContact O-NE2 2.67Å; L644-Q647 PolarHBondContact O-NE2 3.35Å; Q647-N670 VanDerWaalsContact O-CB 3.29Å; Q647-N670 WeakPolarHBondContact O-CB 3.3Å; Q647-N670 PolarHBondContact O-ND2 3.45Å; Q647-F673 WeakPolarHBondContact O-CD2 3.29Å
648V89.2Confident85Confident1 Ų158.2 Ų58.21%0.00633%0.326CS..SBendtrans-72.3-43.2-176.1178.70000110.7F585 L594 L604 L638 N670 F673 L689F585-V648 HydrophobicContact CD2-CG1 4.39Å; F585-V648 HydrophobicContact CE2-CG1 3.97Å; F585-V648 HydrophobicContact CZ-CG1 4.11Å; L594-V648 HydrophobicContact CD1-CG1 4.08Å; L594-V648 HydrophobicContact CD1-CG2 4.25Å; L604-V648 HydrophobicContact CD2-CG1 4.07Å; L638-V648 PolarHBondContact O-N 3Å; V648-N670 VanDerWaalsContact O-CB 3.3Å; V648-N670 WeakPolarHBondContact O-CB 3.15Å; V648-N670 PolarHBondContact O-N 2.74Å; V648-F673 HydrophobicContact CG2-CD2 4.31Å; V648-F673 HydrophobicContact CG2-CE2 3.81Å; V648-F673 HydrophobicContact CG2-CZ 3.98Å; V648-L689 HydrophobicContact CG2-CD1 3.73Å
649L91.5Very high84.7Confident1 Ų166.5 Ų66.51%0.00536%0.362CS..EExtended strand (participates in β ladder)trans-108.4149.2174.3-63.8-177000110.1V603 L604 W607 L635 L638 V639 Y668 V669V603-L649 HydrophobicContact CG1-CD1 4.43Å; L604-L649 HydrophobicContact CD2-CD1 4.38Å; L604-L649 HydrophobicContact CD2-CD2 4.01Å; L604-L649 HydrophobicContact CD2-CG 4.24Å; W607-L649 HydrophobicContact CE3-CD2 4.38Å; W607-L649 HydrophobicContact CH2-CD1 3.91Å; W607-L649 HydrophobicContact CH2-CD2 4.29Å; W607-L649 HydrophobicContact CZ3-CD1 3.94Å; W607-L649 HydrophobicContact CZ3-CD2 4.14Å; L635-L649 HydrophobicContact CD2-CD1 4.2Å; L638-L649 HydrophobicContact CB-CB 4.32Å; L638-L649 HydrophobicContact CB-CD1 3.77Å; L638-L649 HydrophobicContact CB-CG 3.97Å; L638-L649 HydrophobicContact CD1-CD1 3.73Å; L638-L649 HydrophobicContact CD1-CG 4.49Å; L638-L649 HydrophobicContact CG-CD1 4.39Å; L638-L649 PolarHBondContact O-N 3.22Å; L638-L649 VanDerWaalsContact O-N 3.14Å; V639-L649 HydrophobicContact CG1-CB 3.62Å; L649-Y668 WeakPolarHBondContact CA-O 3.48Å; L649-V669 HydrophobicContact CD2-CG2 4.12Å
650S90.9Very high84.5Confident28 Ų2870 Ų7020%0.19638%0.381CS..EExtended strand (participates in β ladder)trans-115.1156.5167.8-650000108.9F667 Y668S650-F667 WeakPolarHBondContact O-CA 3.44Å; S650-Y668 PolarHBondContact N-O 2.7Å; S650-Y668 PolarHBondContact O-N 2.87Å
651Y92.5Very high84.5Confident48 Ų4868.9 Ų68.919%0.18837%0.37CS..EExtended strand (participates in β ladder)trans-150.8156.7-174.569.7-79.1000111.9V639 P653 V655 F661 T665 L666 F667V639-Y651 HydrophobicContact CB-CD1 3.52Å; V639-Y651 HydrophobicContact CB-CE1 3.73Å; V639-Y651 HydrophobicContact CG1-CD1 3.61Å; V639-Y651 HydrophobicContact CG1-CE1 4.33Å; V639-Y651 HydrophobicContact CG1-CG 4.29Å; V639-Y651 HydrophobicContact CG2-CD1 3.87Å; V639-Y651 HydrophobicContact CG2-CE1 3.79Å; Y651-P653 VanDerWaalsContact CD2-O 3.26Å; Y651-P653 WeakPolarHBondContact CD2-O 3.41Å; Y651-P653 VanDerWaalsContact CE2-O 3.28Å; Y651-P653 WeakPolarHBondContact CE2-O 3.4Å; Y651-V655 HydrophobicContact CE2-CB 4.4Å; Y651-V655 HydrophobicContact CE2-CG2 3.76Å; Y651-V655 VanDerWaalsContact CE2-N 3.32Å; Y651-V655 PolarHBondContact OH-N 3.11Å; Y651-V655 PolarHBondContact OH-O 2.88Å; Y651-F661 AromaticContact CD2-CE1 3.92Å; Y651-F661 HydrophobicContact CD2-CE1 3.92Å; Y651-F661 AromaticContact CE2-CE1 3.95Å; Y651-F661 HydrophobicContact CE2-CE1 3.95Å; Y651-F661 HydrophobicContact CG-CE1 4.44Å; Y651-T665 HydrophobicContact CD2-CG2 4.23Å; Y651-L666 CarbonylContact C-O 3.56Å; Y651-L666 WeakPolarHBondContact CA-O 3.34Å; Y651-L666 WeakPolarHBondContact CB-O 3.27Å; Y651-F667 HydrophobicContact CG-CD1 4.44Å; Y651-F667 HydrophobicContact CG-CE1 4.2Å
652D87.6Confident84.7Confident86 Ų8671.1 Ų71.146%0.4639%0.386SS..EExtended strand (participates in β ladder)trans-146.5129.2-176.5-174.333000109.4L666D652-L666 PolarHBondContact N-O 3.32Å; D652-L666 PolarHBondContact O-N 3.03Å
653P85.6Confident85.3Confident70 Ų7069.2 Ų69.246%0.45537%0.369SS..SBendcis-73.2157.2-1.331.1-35.6000114Y651Y651-P653 VanDerWaalsContact CD2-O 3.26Å; Y651-P653 WeakPolarHBondContact CD2-O 3.41Å; Y651-P653 VanDerWaalsContact CE2-O 3.28Å; Y651-P653 WeakPolarHBondContact CE2-O 3.4Å
654S82.5Confident85.8Confident105 Ų10563.7 Ų63.773%0.73436%0.359SS*.  trans-69131.3177.761.60000111.9
655V82.4Confident86.2Confident24 Ų2462.4 Ų62.415%0.14535%0.352CS..  trans-134.6149.5-176.7-57.10000110.9W636 Y651 D660 F661W636-V655 HydrophobicContact CZ3-CG2 4.23Å; Y651-V655 HydrophobicContact CE2-CB 4.4Å; Y651-V655 HydrophobicContact CE2-CG2 3.76Å; Y651-V655 VanDerWaalsContact CE2-N 3.32Å; Y651-V655 PolarHBondContact OH-N 3.11Å; Y651-V655 PolarHBondContact OH-O 2.88Å; V655-D660 HydrophobicContact CB-CB 3.82Å; V655-D660 HydrophobicContact CG1-CB 4.09Å; V655-D660 HydrophobicContact CG2-CB 4.25Å; V655-F661 HydrophobicContact CG2-CD1 3.4Å; V655-F661 HydrophobicContact CG2-CE1 3.33Å; V655-F661 HydrophobicContact CG2-CG 4.38Å; V655-F661 HydrophobicContact CG2-CZ 4.28Å
656S78.4Confident86.7Confident114 Ų11457.7 Ų57.780%0.79733%0.334SS*.SBendtrans-92.3-12.8-174.4-570000113.9W636W636-S656 WeakPolarHBondContact CH2-O 3.43Å; W636-S656 WeakPolarHBondContact CZ2-O 3.43Å
657S80.7Confident87.1Confident34 Ų3454.7 Ų54.724%0.23832%0.321CS..SBendtrans-140.5155.8178950000113.3K659 D660S657-K659 PolarHBondContact O-N 3.21Å; S657-K659 PolarHBondContact OG-N 3.48Å; S657-D660 WeakPolarHBondContact CB-OD2 3.44Å; S657-D660 PolarHBondContact N-OD2 2.93Å; S657-D660 VanDerWaalsContact N-OD2 3.16Å; S657-D660 PolarHBondContact O-N 2.98Å; S657-D660 VanDerWaalsContact O-N 3.14Å; S657-D660 PolarHBondContact OG-OD1 2.81Å; S657-D660 PolarHBondContact OG-OD2 3.28Å
658P80.2Confident87.3Confident40 Ų4056.3 Ų56.326%0.2633%0.326SS..G310 helixtrans-61.7-23.5175.821.9-32000114R632 W636 D660 F661R632-P658 HydrophobicContact CB-CB 4.3Å; R632-P658 WeakPolarHBondContact CD-O 3.49Å; R632-P658 PolarHBondContact NH1-O 2.59Å; W636-P658 HydrophobicContact CB-CB 3.93Å; W636-P658 HydrophobicContact CD2-CB 4.17Å; W636-P658 HydrophobicContact CD2-CG 4.31Å; W636-P658 HydrophobicContact CE3-CB 4.24Å; W636-P658 HydrophobicContact CG-CB 4.03Å; W636-P658 HydrophobicContact CG-CG 4.22Å; P658-D660 VanDerWaalsContact C-N 3.25Å; P658-D660 PolarHBondContact O-N 3.08Å; P658-F661 HydrophobicContact CB-CE2 4.44Å; P658-F661 VanDerWaalsContact O-CD2 3.29Å; P658-F661 WeakPolarHBondContact O-CD2 3.44Å
659K82.9Confident87.5Confident176 Ų17656.9 Ų56.977%0.76533%0.33SS*.G310 helixtrans-74.6-21.2179.9-65.3-178.1178.7-178.90112.1R632 S657 F661R632-K659 PolarHBondContact NH1-O 3.14Å; S657-K659 PolarHBondContact O-N 3.21Å; S657-K659 PolarHBondContact OG-N 3.48Å; K659-F661 VanDerWaalsContact C-N 3.33Å
660D84.2Confident87.4Confident82 Ų8258 Ų5844%0.43934%0.335SS..G310 helixtrans-87.6-3.2-174.6-54-37.4000112.7V655 S657 P658 T662V655-D660 HydrophobicContact CB-CB 3.82Å; V655-D660 HydrophobicContact CG1-CB 4.09Å; V655-D660 HydrophobicContact CG2-CB 4.25Å; S657-D660 WeakPolarHBondContact CB-OD2 3.44Å; S657-D660 PolarHBondContact N-OD2 2.93Å; S657-D660 VanDerWaalsContact N-OD2 3.16Å; S657-D660 PolarHBondContact O-N 2.98Å; S657-D660 VanDerWaalsContact O-N 3.14Å; S657-D660 PolarHBondContact OG-OD1 2.81Å; S657-D660 PolarHBondContact OG-OD2 3.28Å; P658-D660 VanDerWaalsContact C-N 3.25Å; P658-D660 PolarHBondContact O-N 3.08Å; D660-T662 PolarHBondContact O-N 3.26Å
661F86.5Confident87.3Confident4 Ų458.3 Ų58.32%0.01833%0.334CS..  trans-61.9137171.3-61.1-48000110.3F617 R632 L635 W636 V639 Y651 V655 P658 K659 T665 F667F617-F661 HydrophobicContact CD2-CB 4.46Å; R632-F661 HydrophobicContact CB-CD2 4.4Å; R632-F661 HydrophobicContact CG-CD2 4.29Å; R632-F661 VanDerWaalsContact CZ-O 3.26Å; R632-F661 PolarHBondContact NH1-O 2.91Å; R632-F661 PolarHBondContact NH2-O 3.49Å; L635-F661 HydrophobicContact CB-CE2 4.27Å; W636-F661 HydrophobicContact CB-CE2 4.43Å; W636-F661 HydrophobicContact CE3-CE1 4.4Å; W636-F661 AromaticContact CE3-CE2 3.93Å; W636-F661 HydrophobicContact CE3-CE2 3.93Å; W636-F661 AromaticContact CE3-CZ 3.56Å; W636-F661 HydrophobicContact CE3-CZ 3.56Å; W636-F661 HydrophobicContact CZ3-CE1 4.49Å; W636-F661 HydrophobicContact CZ3-CZ 4.06Å; V639-F661 HydrophobicContact CG2-CZ 3.97Å; Y651-F661 AromaticContact CD2-CE1 3.92Å; Y651-F661 HydrophobicContact CD2-CE1 3.92Å; Y651-F661 AromaticContact CE2-CE1 3.95Å; Y651-F661 HydrophobicContact CE2-CE1 3.95Å; Y651-F661 HydrophobicContact CG-CE1 4.44Å; V655-F661 HydrophobicContact CG2-CD1 3.4Å; V655-F661 HydrophobicContact CG2-CE1 3.33Å; V655-F661 HydrophobicContact CG2-CG 4.38Å; V655-F661 HydrophobicContact CG2-CZ 4.28Å; P658-F661 HydrophobicContact CB-CE2 4.44Å; P658-F661 VanDerWaalsContact O-CD2 3.29Å; P658-F661 WeakPolarHBondContact O-CD2 3.44Å; K659-F661 VanDerWaalsContact C-N 3.33Å; F661-T665 HydrophobicContact CD1-CG2 4.01Å; F661-F667 HydrophobicContact CD1-CE1 4.36Å; F661-F667 AromaticContact CD1-CZ 3.76Å; F661-F667 HydrophobicContact CD1-CZ 3.76Å; F661-F667 HydrophobicContact CD2-CZ 4.24Å; F661-F667 AromaticContact CE1-CE1 3.88Å; F661-F667 HydrophobicContact CE1-CE1 3.88Å; F661-F667 AromaticContact CE1-CZ 3.75Å; F661-F667 HydrophobicContact CE1-CZ 3.75Å; F661-F667 HydrophobicContact CE2-CE1 4.45Å; F661-F667 HydrophobicContact CE2-CZ 4.24Å; F661-F667 HydrophobicContact CG-CZ 4Å; F661-F667 AromaticContact CZ-CE1 3.92Å; F661-F667 HydrophobicContact CZ-CE1 3.92Å; F661-F667 AromaticContact CZ-CZ 3.98Å; F661-F667 HydrophobicContact CZ-CZ 3.98Å
662T88.3Confident87Confident73 Ų7362.2 Ų62.245%0.44835%0.354SS..  trans-108162174.960.80000109F617 D660 A664 T665F617-T662 VanDerWaalsContact CB-O 3.3Å; F617-T662 WeakPolarHBondContact CB-O 3.34Å; D660-T662 PolarHBondContact O-N 3.26Å; T662-A664 PolarHBondContact O-N 3.2Å; T662-A664 VanDerWaalsContact O-N 3.13Å; T662-T665 PolarHBondContact N-OG1 3.49Å; T662-T665 VanDerWaalsContact O-CB 3.3Å; T662-T665 WeakPolarHBondContact O-CB 3.32Å; T662-T665 PolarHBondContact O-N 2.72Å; T662-T665 PolarHBondContact O-OG1 3.46Å; T662-T665 PolarHBondContact OG1-N 3.34Å; T662-T665 PolarHBondContact OG1-OG1 2.85Å
663D88.6Confident87Confident86 Ų8658.1 Ų58.146%0.4633%0.332SS..THydrogen-bonded Turntrans-58.8-27.6178.1-64.4-28.8000112.2F617 E618F617-D663 PolarHBondContact N-O 2.81Å; E618-D663 HydrophobicContact CB-CB 4.31Å; E618-D663 PolarHBondContact N-O 3.37Å
664A89.4Confident87Confident76 Ų7655 Ų5563%0.62831%0.312SS*.THydrogen-bonded Turntrans-83.6-8.5175.800000114.7T662 L666T662-A664 PolarHBondContact O-N 3.2Å; T662-A664 VanDerWaalsContact O-N 3.13Å; A664-L666 PolarHBondContact O-N 3.27Å
665T91.5Very high87.1Confident0 Ų051.9 Ų51.90%029%0.287CS..  trans-62.1124.8-179.9-62.20000109.7S616 F617 Y651 F661 T662 F667S616-T665 CarbonylContact C-O 3.42Å; S616-T665 WeakPolarHBondContact CA-O 3.41Å; F617-T665 PolarHBondContact N-O 3.04Å; Y651-T665 HydrophobicContact CD2-CG2 4.23Å; F661-T665 HydrophobicContact CD1-CG2 4.01Å; T662-T665 PolarHBondContact N-OG1 3.49Å; T662-T665 VanDerWaalsContact O-CB 3.3Å; T662-T665 WeakPolarHBondContact O-CB 3.32Å; T662-T665 PolarHBondContact O-N 2.72Å; T662-T665 PolarHBondContact O-OG1 3.46Å; T662-T665 PolarHBondContact OG1-N 3.34Å; T662-T665 PolarHBondContact OG1-OG1 2.85Å; T665-F667 HydrophobicContact CG2-CD2 4.41Å; T665-F667 HydrophobicContact CG2-CE1 4.48Å; T665-F667 HydrophobicContact CG2-CE2 3.7Å; T665-F667 HydrophobicContact CG2-CZ 3.75Å; T665-F667 WeakPolarHBondContact O-CD2 3.19Å
666L92.4Very high87.1Confident61 Ų6153.5 Ų53.532%0.31929%0.294SS..EExtended strand (participates in β ladder)trans-94.6131.5-176.9-63.8178.3000110.3K614 Y651 D652 A664K614-L666 HydrophobicContact CB-CB 4.3Å; K614-L666 HydrophobicContact CB-CD1 4.44Å; K614-L666 HydrophobicContact CD-CD1 4.21Å; Y651-L666 CarbonylContact C-O 3.56Å; Y651-L666 WeakPolarHBondContact CA-O 3.34Å; Y651-L666 WeakPolarHBondContact CB-O 3.27Å; D652-L666 PolarHBondContact N-O 3.32Å; D652-L666 PolarHBondContact O-N 3.03Å; A664-L666 PolarHBondContact O-N 3.27Å
667F94.1Very high87.2Confident0 Ų054.6 Ų54.60%028%0.284CS..EExtended strand (participates in β ladder)trans-115.1144175.9-62.4-92.8000110.3W607 K614 I615 F617 L620 L635 V639 S650 Y651 F661 T665W607-F667 HydrophobicContact CH2-CB 4.02Å; W607-F667 HydrophobicContact CZ2-CB 3.82Å; W607-F667 WeakPolarHBondContact CZ2-O 3.3Å; K614-F667 CarbonylContact C-O 3.59Å; K614-F667 WeakPolarHBondContact CA-O 3.18Å; I615-F667 PolarHBondContact N-O 3.43Å; I615-F667 PolarHBondContact O-N 3.42Å; F617-F667 HydrophobicContact CB-CE2 4.06Å; F617-F667 HydrophobicContact CD2-CE2 4.15Å; L620-F667 HydrophobicContact CD1-CB 4Å; L620-F667 HydrophobicContact CD1-CD2 3.81Å; L620-F667 HydrophobicContact CD1-CG 4.1Å; L635-F667 HydrophobicContact CB-CE1 4.16Å; L635-F667 HydrophobicContact CB-CZ 4.42Å; L635-F667 HydrophobicContact CD1-CD2 4.41Å; L635-F667 HydrophobicContact CD1-CE1 4.25Å; L635-F667 HydrophobicContact CD1-CE2 3.95Å; L635-F667 HydrophobicContact CD1-CZ 3.87Å; L635-F667 HydrophobicContact CD2-CD1 4.09Å; L635-F667 HydrophobicContact CD2-CE1 4.27Å; L635-F667 HydrophobicContact CD2-CG 4.3Å; L635-F667 HydrophobicContact CG-CE1 4.48Å; V639-F667 HydrophobicContact CG1-CD1 3.96Å; V639-F667 HydrophobicContact CG1-CE1 4.08Å; S650-F667 WeakPolarHBondContact O-CA 3.44Å; Y651-F667 HydrophobicContact CG-CD1 4.44Å; Y651-F667 HydrophobicContact CG-CE1 4.2Å; F661-F667 HydrophobicContact CD1-CE1 4.36Å; F661-F667 AromaticContact CD1-CZ 3.76Å; F661-F667 HydrophobicContact CD1-CZ 3.76Å; F661-F667 HydrophobicContact CD2-CZ 4.24Å; F661-F667 AromaticContact CE1-CE1 3.88Å; F661-F667 HydrophobicContact CE1-CE1 3.88Å; F661-F667 AromaticContact CE1-CZ 3.75Å; F661-F667 HydrophobicContact CE1-CZ 3.75Å; F661-F667 HydrophobicContact CE2-CE1 4.45Å; F661-F667 HydrophobicContact CE2-CZ 4.24Å; F661-F667 HydrophobicContact CG-CZ 4Å; F661-F667 AromaticContact CZ-CE1 3.92Å; F661-F667 HydrophobicContact CZ-CE1 3.92Å; F661-F667 AromaticContact CZ-CZ 3.98Å; F661-F667 HydrophobicContact CZ-CZ 3.98Å; T665-F667 HydrophobicContact CG2-CD2 4.41Å; T665-F667 HydrophobicContact CG2-CE1 4.48Å; T665-F667 HydrophobicContact CG2-CE2 3.7Å; T665-F667 HydrophobicContact CG2-CZ 3.75Å; T665-F667 WeakPolarHBondContact O-CD2 3.19Å
668Y93.3Very high87Confident73 Ų7360 Ų6029%0.28631%0.311SS..EExtended strand (participates in β ladder)trans-151.3156.4177.755.4-83.2000112.1K614 L649 S650K614-Y668 HydrophobicContact CD-CD1 4.12Å; K614-Y668 HydrophobicContact CG-CD1 3.92Å; K614-Y668 HydrophobicContact CG-CG 4.14Å; L649-Y668 WeakPolarHBondContact CA-O 3.48Å; S650-Y668 PolarHBondContact N-O 2.7Å; S650-Y668 PolarHBondContact O-N 2.87Å
669V93.2Very high87Confident14 Ų1463.1 Ų63.19%0.08533%0.334CS..EExtended strand (participates in β ladder)trans-69.6129.8180179.60000110.6F585 W607 L649 Q671F585-V669 HydrophobicContact CE2-CG1 3.57Å; F585-V669 HydrophobicContact CZ-CG1 3.42Å; F585-V669 VanDerWaalsContact CZ-CG1 3.42Å; W607-V669 HydrophobicContact CB-CG2 3.57Å; W607-V669 HydrophobicContact CD2-CG2 3.91Å; W607-V669 HydrophobicContact CE3-CG2 4.47Å; W607-V669 HydrophobicContact CG-CG2 3.5Å; W607-V669 VanDerWaalsContact CG-CG2 3.5Å; L649-V669 HydrophobicContact CD2-CG2 4.12Å; V669-Q671 PolarHBondContact O-N 3.21Å; V669-Q671 VanDerWaalsContact O-N 3.14Å
670N91.1Very high87Confident23 Ų2361.9 Ų61.912%0.12333%0.328CS..  trans-77.899.2176.4-174.80.9000110.8Q647 V648 E672 F673Q647-N670 VanDerWaalsContact O-CB 3.29Å; Q647-N670 WeakPolarHBondContact O-CB 3.3Å; Q647-N670 PolarHBondContact O-ND2 3.45Å; V648-N670 VanDerWaalsContact O-CB 3.3Å; V648-N670 WeakPolarHBondContact O-CB 3.15Å; V648-N670 PolarHBondContact O-N 2.74Å; N670-E672 PolarHBondContact O-N 3.3Å; N670-E672 PolarHBondContact OD1-N 3.21Å; N670-E672 VanDerWaalsContact OD1-N 3.08Å; N670-F673 HydrophobicContact CB-CB 4.18Å; N670-F673 WeakPolarHBondContact O-CB 3.45Å; N670-F673 PolarHBondContact O-N 3.44Å; N670-F673 VanDerWaalsContact O-N 3.08Å; N670-F673 PolarHBondContact OD1-N 3.48Å
671Q88.1Confident87.1Confident36 Ų3661.9 Ų61.917%0.16833%0.331CS..THydrogen-bonded Turntrans-65.9-22.1179.5-63.7-59.1-23.300113.2N587 E588 P611 V669 F673N587-Q671 PolarHBondContact ND2-O 3.23Å; E588-Q671 HydrophobicContact CG-CB 4.14Å; P611-Q671 PolarHBondContact O-NE2 3.27Å; V669-Q671 PolarHBondContact O-N 3.21Å; V669-Q671 VanDerWaalsContact O-N 3.14Å; Q671-F673 VanDerWaalsContact C-N 3.33Å
672E86.9Confident87Confident129 Ų12965.1 Ų65.160%0.60335%0.346SS*.THydrogen-bonded Turntrans-89.84.8175.6-58.5-169.3176.400114K646 N670 S674K646-E672 WeakPolarHBondContact CD-O 3.43Å; K646-E672 PolarHBondContact NZ-O 2.93Å; K646-E672 IonicContact NZ-OE2 3.29Å; N670-E672 PolarHBondContact O-N 3.3Å; N670-E672 PolarHBondContact OD1-N 3.21Å; N670-E672 VanDerWaalsContact OD1-N 3.08Å; E672-S674 PolarHBondContact O-N 3.17Å
673F87.3Confident86.9Confident1 Ų169 Ų690%0.00436%0.357CS..  trans-54.8132.1-179.9171.8-100.5000111F585 N587 Y592 L594 L644 K646 Q647 V648 N670 Q671 I687F585-F673 AromaticContact CD1-CD1 3.93Å; F585-F673 HydrophobicContact CD1-CD1 3.93Å; F585-F673 HydrophobicContact CD1-CE1 4.28Å; F585-F673 HydrophobicContact CE1-CB 4.16Å; F585-F673 AromaticContact CE1-CD1 3.66Å; F585-F673 HydrophobicContact CE1-CD1 3.66Å; F585-F673 HydrophobicContact CE1-CE1 4.4Å; F585-F673 HydrophobicContact CE1-CG 4.17Å; N587-F673 WeakPolarHBondContact ND2-CB 3.28Å; N587-F673 PolarHBondContact ND2-N 3.48Å; N587-F673 PolarHBondContact ND2-O 3.43Å; Y592-F673 HydrophobicContact CD1-CE1 4.42Å; Y592-F673 AromaticContact CD2-CD1 3.8Å; Y592-F673 HydrophobicContact CD2-CD1 3.8Å; Y592-F673 AromaticContact CD2-CE1 3.81Å; Y592-F673 HydrophobicContact CD2-CE1 3.81Å; Y592-F673 AromaticContact CE2-CD1 3.94Å; Y592-F673 HydrophobicContact CE2-CD1 3.94Å; Y592-F673 HydrophobicContact CE2-CE1 4.27Å; Y592-F673 HydrophobicContact CG-CD1 4.35Å; Y592-F673 AromaticContact CG-CE1 3.89Å; Y592-F673 HydrophobicContact CG-CE1 3.89Å; Y592-F673 PolarHBondContact OH-O 2.97Å; L594-F673 HydrophobicContact CD2-CE1 4.42Å; L594-F673 HydrophobicContact CD2-CZ 4.45Å; L644-F673 HydrophobicContact CD1-CE2 4.3Å; K646-F673 HydrophobicContact CB-CD2 4.33Å; K646-F673 WeakPolarHBondContact O-CD2 3.28Å; K646-F673 WeakPolarHBondContact O-CE2 3.39Å; Q647-F673 WeakPolarHBondContact O-CD2 3.29Å; V648-F673 HydrophobicContact CG2-CD2 4.31Å; V648-F673 HydrophobicContact CG2-CE2 3.81Å; V648-F673 HydrophobicContact CG2-CZ 3.98Å; N670-F673 HydrophobicContact CB-CB 4.18Å; N670-F673 WeakPolarHBondContact O-CB 3.45Å; N670-F673 PolarHBondContact O-N 3.44Å; N670-F673 VanDerWaalsContact O-N 3.08Å; N670-F673 PolarHBondContact OD1-N 3.48Å; Q671-F673 VanDerWaalsContact C-N 3.33Å; F673-I687 HydrophobicContact CE1-CD1 3.99Å; F673-I687 HydrophobicContact CZ-CD1 3.46Å; F673-I687 VanDerWaalsContact CZ-CD1 3.46Å
674S85.9Confident86.8Confident5 Ų574.1 Ų74.14%0.03537%0.37CS..  trans-157143.1178.274.20000112.6Y592 E672 I676Y592-S674 VanDerWaalsContact OH-CA 3.28Å; Y592-S674 WeakPolarHBondContact OH-CA 3.27Å; Y592-S674 WeakPolarHBondContact OH-CB 3.35Å; E672-S674 PolarHBondContact O-N 3.17Å; S674-I676 PolarHBondContact O-N 3.49Å
675L83.1Confident86.7Confident39 Ų3971.7 Ų71.720%0.20435%0.352CS..EExtended strand (participates in β ladder)trans-76.3123.6174-172.9139.3000109.9Y592 K677 Q682 I687Y592-L675 HydrophobicContact CD1-CB 4.3Å; Y592-L675 HydrophobicContact CE1-CB 4Å; L675-K677 HydrophobicContact CD2-CB 4.02Å; L675-Q682 HydrophobicContact CB-CB 4.3Å; L675-Q682 HydrophobicContact CD2-CB 4.03Å; L675-Q682 HydrophobicContact CD2-CG 3.63Å; L675-Q682 WeakPolarHBondContact O-CB 3.25Å; L675-Q682 PolarHBondContact O-N 2.79Å; L675-I687 HydrophobicContact CB-CD1 4.44Å; L675-I687 HydrophobicContact CD1-CD1 3.8Å; L675-I687 HydrophobicContact CD1-CG1 3.6Å
676I83.3Confident86.5Confident58 Ų5877.7 Ų77.730%0.29738%0.378SS..EExtended strand (participates in β ladder)trans-104.5111.4179.1-56.9178.8000108.3K645 S674 K680K645-I676 HydrophobicContact CB-CD1 4.01Å; K645-I676 HydrophobicContact CD-CB 4.27Å; K645-I676 HydrophobicContact CD-CD1 4Å; K645-I676 HydrophobicContact CD-CG2 4.26Å; S674-I676 PolarHBondContact O-N 3.49Å; I676-K680 WeakPolarHBondContact CA-O 3.46Å
677K79.7Confident86.3Confident136 Ų13675.3 Ų75.359%0.59137%0.366SS*.EExtended strand (participates in β ladder)trans-119.5126.8174.1-166.2177-177.3-178.60108.7L675 S679 K680 Q682L675-K677 HydrophobicContact CD2-CB 4.02Å; K677-S679 PolarHBondContact O-N 2.91Å; K677-K680 PolarHBondContact N-O 2.96Å; K677-K680 PolarHBondContact O-N 3.28Å; K677-Q682 HydrophobicContact CB-CG 4.18Å
678N77.3Confident85.9Confident148 Ų14878.9 Ų78.979%0.79139%0.385SS*.THydrogen-bonded Turntrans49.844.2-175.6-59.7-9.5000113.1K680N678-K680 PolarHBondContact O-N 3.04Å; N678-K680 VanDerWaalsContact O-N 3.08Å
679S79.9Confident85.5Confident106 Ų10675.4 Ų75.474%0.74137%0.371SS*.THydrogen-bonded Turntrans61.111.9-176.8-55.70000115.7K677K677-S679 PolarHBondContact O-N 2.91Å
680K83.8Confident84.8Confident150 Ų15075.4 Ų75.465%0.65237%0.371SS*.EExtended strand (participates in β ladder)trans-107.5135.6173.9-65.5-175.3-179.5-177.80111.4I676 K677 N678 Q682I676-K680 WeakPolarHBondContact CA-O 3.46Å; K677-K680 PolarHBondContact N-O 2.96Å; K677-K680 PolarHBondContact O-N 3.28Å; N678-K680 PolarHBondContact O-N 3.04Å; N678-K680 VanDerWaalsContact O-N 3.08Å; K680-Q682 PolarHBondContact O-N 3.25Å
681V85.1Confident83.8Confident82 Ų8276.3 Ų76.350%0.49739%0.386SS..EExtended strand (participates in β ladder)trans-71.5122.1174.3174.50000109.4V589V589-V681 HydrophobicContact CG1-CG1 3.9Å
682Q85.4Confident82.8Confident72 Ų7284.6 Ų84.634%0.33642%0.415SS..EExtended strand (participates in β ladder)trans-94.5133.6174.5-57.2-58.3-51.300109.2Y592 L675 K677 K680 R684Y592-Q682 VanDerWaalsContact CE1-O 3.27Å; Y592-Q682 WeakPolarHBondContact CE1-O 3.32Å; Y592-Q682 PolarHBondContact OH-O 2.92Å; L675-Q682 HydrophobicContact CB-CB 4.3Å; L675-Q682 HydrophobicContact CD2-CB 4.03Å; L675-Q682 HydrophobicContact CD2-CG 3.63Å; L675-Q682 WeakPolarHBondContact O-CB 3.25Å; L675-Q682 PolarHBondContact O-N 2.79Å; K677-Q682 HydrophobicContact CB-CG 4.18Å; K680-Q682 PolarHBondContact O-N 3.25Å; Q682-R684 VanDerWaalsContact C-N 3.34Å
683K85.8Confident81.8Confident154 Ų15479.4 Ų79.467%0.6739%0.392SS*.SBendtrans-83.6-11.1176.5-62.8-173.1177.4-174.60113.5G590 Q591G590-K683 VanDerWaalsContact CA-O 3.29Å; G590-K683 WeakPolarHBondContact CA-O 3.45Å; Q591-K683 PolarHBondContact N-O 2.73Å
684R87Confident80.9Confident193 Ų19379.8 Ų79.873%0.72839%0.394SS*.EExtended strand (participates in β ladder)trans-143.6152176.4-64.5-174.4179.1179.6-1111.1Q591 Q682Q591-R684 VanDerWaalsContact O-CA 3.25Å; Q591-R684 WeakPolarHBondContact O-CA 2.96Å; Q682-R684 VanDerWaalsContact C-N 3.34Å
685G86.8Confident79.9Confident26 Ų2681.4 Ų81.427%0.26840%0.402SS..EExtended strand (participates in β ladder)trans170.1164.2174.200000112.9Y592 D593Y592-G685 CarbonylContact C-O 3.5Å; Y592-G685 VanDerWaalsContact CA-O 3.32Å; Y592-G685 WeakPolarHBondContact CA-O 3.47Å; D593-G685 PolarHBondContact N-O 3.37Å
686K87.8Confident79Confident125 Ų12582.6 Ų82.654%0.54341%0.41SS..EExtended strand (participates in β ladder)trans-106.1136.5175.3-174177179.4-179.70110.6D593D593-K686 HydrophobicContact CB-CB 4.38Å; D593-K686 HydrophobicContact CB-CG 4.27Å; D593-K686 CarbonylContact O-C 3.54Å; D593-K686 VanDerWaalsContact O-CA 3.28Å; D593-K686 WeakPolarHBondContact O-CA 3.39Å
687I87.6Confident78.3Confident12 Ų1281.7 Ų81.76%0.06241%0.407CS..EExtended strand (participates in β ladder)trans-135.1131-176.7-57.3171.3000109.2D593 L594 E595 L644 F673 L675 L689D593-I687 PolarHBondContact O-N 2.88Å; L594-I687 HydrophobicContact CD2-CB 4Å; L594-I687 HydrophobicContact CD2-CD1 4.13Å; L594-I687 HydrophobicContact CD2-CG1 4.48Å; E595-I687 PolarHBondContact N-O 3.18Å; L644-I687 HydrophobicContact CD1-CG2 4.24Å; L644-I687 HydrophobicContact CD2-CD1 4.34Å; L644-I687 HydrophobicContact CD2-CG2 4.21Å; F673-I687 HydrophobicContact CE1-CD1 3.99Å; F673-I687 HydrophobicContact CZ-CD1 3.46Å; F673-I687 VanDerWaalsContact CZ-CD1 3.46Å; L675-I687 HydrophobicContact CB-CD1 4.44Å; L675-I687 HydrophobicContact CD1-CD1 3.8Å; L675-I687 HydrophobicContact CD1-CG1 3.6Å; I687-L689 HydrophobicContact CG2-CD2 3.83Å; I687-L689 HydrophobicContact CG2-CG 4.04Å
688N86.4Confident77.8Confident74 Ų7479.8 Ų79.840%0.39640%0.401SS..EExtended strand (participates in β ladder)trans-96114.3171.5-175.1-36.4000110.3E595 F641 I690E595-N688 HydrophobicContact CB-CB 4.37Å; E595-N688 PolarHBondContact OE1-ND2 3.21Å; E595-N688 WeakPolarHBondContact OE2-CB 3.3Å; E595-N688 PolarHBondContact OE2-ND2 3Å; F641-N688 WeakPolarHBondContact CZ-O 3.43Å; N688-I690 WeakPolarHBondContact OD1-CB 3.28Å; N688-I690 PolarHBondContact OD1-N 3.41Å
689L83.7Confident77.5Confident1 Ų178.1 Ų78.11%0.00538%0.383CS..  trans-105-1.4-179.8-64.9176.4000113L594 E595 V596 Q600 L638 F641 L644 V648 I687 G691L594-L689 HydrophobicContact CB-CD1 4.16Å; L594-L689 HydrophobicContact CD1-CD1 3.94Å; L594-L689 HydrophobicContact CD2-CD1 4.04Å; L594-L689 HydrophobicContact CG-CD1 4.27Å; E595-L689 PolarHBondContact O-N 2.92Å; V596-L689 HydrophobicContact CG1-CB 4.1Å; V596-L689 HydrophobicContact CG1-CD1 3.99Å; Q600-L689 PolarHBondContact NE2-O 2.98Å; L638-L689 HydrophobicContact CD2-CD1 4.27Å; F641-L689 HydrophobicContact CD1-CD2 4.37Å; F641-L689 HydrophobicContact CD2-CD2 4.13Å; F641-L689 HydrophobicContact CE2-CD2 4.38Å; F641-L689 HydrophobicContact CG-CD2 4.12Å; L644-L689 HydrophobicContact CD1-CD2 3.52Å; V648-L689 HydrophobicContact CG2-CD1 3.73Å; I687-L689 HydrophobicContact CG2-CD2 3.83Å; I687-L689 HydrophobicContact CG2-CG 4.04Å; L689-G691 VanDerWaalsContact C-N 3.28Å; L689-G691 PolarHBondContact O-N 2.69Å
690I79.6Confident77Confident14 Ų1474.9 Ų74.97%0.07236%0.357CS..  trans-60.9-42.8176.5-61.2174.5000109.7N580 E595 T597 N688 R692 L693 Q694N580-I690 HydrophobicContact CB-CD1 3.66Å; E595-I690 HydrophobicContact CG-CD1 3.73Å; E595-I690 HydrophobicContact CG-CG1 4.33Å; T597-I690 HydrophobicContact CG2-CB 4.31Å; T597-I690 HydrophobicContact CG2-CG1 4.16Å; T597-I690 HydrophobicContact CG2-CG2 3.92Å; N688-I690 WeakPolarHBondContact OD1-CB 3.28Å; N688-I690 PolarHBondContact OD1-N 3.41Å; I690-R692 PolarHBondContact O-N 3.04Å; I690-R692 VanDerWaalsContact O-N 3.17Å; I690-L693 VanDerWaalsContact O-CB 3.29Å; I690-L693 WeakPolarHBondContact O-CB 3.34Å; I690-L693 WeakPolarHBondContact O-CG 3.45Å; I690-L693 PolarHBondContact O-N 3.25Å; I690-Q694 HydrophobicContact CG2-CB 4.31Å; I690-Q694 HydrophobicContact CG2-CG 4.1Å
691G70.3Confident76.6Confident42 Ų4271.4 Ų71.443%0.43334%0.34SS..THydrogen-bonded Turntrans52.2-119.7173.200000113.2L689L689-G691 VanDerWaalsContact C-N 3.28Å; L689-G691 PolarHBondContact O-N 2.69Å
692R66.5Low76.1Confident209 Ų20971.4 Ų71.479%0.78934%0.335SS*.THydrogen-bonded Turntrans-101.15178.2-57.4-167.9174.4175.9-2.9113.6I690 Q694 L695I690-R692 PolarHBondContact O-N 3.04Å; I690-R692 VanDerWaalsContact O-N 3.17Å; R692-Q694 VanDerWaalsContact C-N 3.27Å; R692-Q694 PolarHBondContact O-N 3.18Å; R692-L695 HydrophobicContact CB-CB 4.42Å; R692-L695 HydrophobicContact CB-CD1 3.9Å; R692-L695 HydrophobicContact CB-CG 4.39Å; R692-L695 HydrophobicContact CG-CD1 3.81Å; R692-L695 WeakPolarHBondContact O-CB 3.36Å; R692-L695 PolarHBondContact O-N 3.1Å
693L66.2Low75.7Confident21 Ų2171 Ų7111%0.1133%0.333CS..THydrogen-bonded Turntrans-66.9-29.8-172.1-65.3167.9000113.2T597 Q600 R633 S637 I690T597-L693 HydrophobicContact CG2-CB 4.25Å; T597-L693 HydrophobicContact CG2-CD1 4.37Å; Q600-L693 HydrophobicContact CG-CD1 4.14Å; R633-L693 HydrophobicContact CG-CD2 3.75Å; R633-L693 PolarHBondContact NH1-O 2.9Å; R633-L693 PolarHBondContact NH2-O 3.48Å; S637-L693 VanDerWaalsContact CB-CD1 3.48Å; S637-L693 VanDerWaalsContact OG-CD1 3.28Å; S637-L693 WeakPolarHBondContact OG-CD1 3.37Å; I690-L693 VanDerWaalsContact O-CB 3.29Å; I690-L693 WeakPolarHBondContact O-CB 3.34Å; I690-L693 WeakPolarHBondContact O-CG 3.45Å; I690-L693 PolarHBondContact O-N 3.25Å
694Q67Low75.4Confident9 Ų964.9 Ų64.94%0.04231%0.306CS..THydrogen-bonded Turntrans-98.97.7175.3-64.5178.8-43.900112.5L465 L577 S579 T597 I690 R692L465-Q694 HydrophobicContact CD1-CB 3.91Å; L577-Q694 PolarHBondContact O-NE2 2.96Å; S579-Q694 PolarHBondContact O-NE2 3.25Å; T597-Q694 HydrophobicContact CG2-CG 3.75Å; I690-Q694 HydrophobicContact CG2-CB 4.31Å; I690-Q694 HydrophobicContact CG2-CG 4.1Å; R692-Q694 VanDerWaalsContact C-N 3.27Å; R692-Q694 PolarHBondContact O-N 3.18Å
695L66.6Low75.1Confident39 Ų3956.1 Ų56.120%0.20427%0.274CS..SBendtrans-87.1164.1171.5-61.7-179.4000111.1R692 T697R692-L695 HydrophobicContact CB-CB 4.42Å; R692-L695 HydrophobicContact CB-CD1 3.9Å; R692-L695 HydrophobicContact CB-CG 4.39Å; R692-L695 HydrophobicContact CG-CD1 3.81Å; R692-L695 WeakPolarHBondContact O-CB 3.36Å; R692-L695 PolarHBondContact O-N 3.1Å; L695-T697 PolarHBondContact O-N 2.99Å
696T64Low74.8Confident63 Ų6357.4 Ų57.439%0.38727%0.273SS..PPolyproline II helixtrans-49.4120.4176.921.10000111.8R461R461-T696 VanDerWaalsContact CZ-CG2 3.48Å
697T69.1Low74.6Confident39 Ų3952.4 Ų52.424%0.23926%0.256CS..PPolyproline II helixtrans-91.2164.3166.464.80000110.3R633 L695 R699 M700 R701R633-T697 VanDerWaalsContact NH1-CG2 3.25Å; L695-T697 PolarHBondContact O-N 2.99Å; T697-R699 PolarHBondContact O-N 2.93Å; T697-M700 PolarHBondContact O-N 3.05Å; T697-M700 WeakPolarHBondContact OG1-CG 3.33Å; T697-M700 PolarHBondContact OG1-N 3.46Å; T697-M700 VanDerWaalsContact OG1-N 3.17Å; T697-R701 PolarHBondContact O-N 3.45Å
698E68Low74.5Confident97 Ų9752 Ų5245%0.45326%0.255SS..Hα-helixtrans-55.7-42.9172.8-173.753.2-131.300111.7M700 R701 E702E698-M700 PolarHBondContact O-N 3.32Å; E698-R701 VanDerWaalsContact CD-CZ 3.44Å; E698-R701 WeakPolarHBondContact O-CA 3.44Å; E698-R701 VanDerWaalsContact O-CB 3.28Å; E698-R701 WeakPolarHBondContact O-CB 3.01Å; E698-R701 PolarHBondContact O-N 3.16Å; E698-R701 VanDerWaalsContact O-N 3.1Å; E698-R701 IonicContact OE1-CZ 3.14Å; E698-R701 IonicContact OE1-NE 3.13Å; E698-R701 PolarHBondContact OE1-NE 3.11Å; E698-R701 IonicContact OE1-NH2 3.82Å; E698-R701 PolarHBondContact OE1-NH2 3.38Å; E698-R701 IonicContact OE2-CZ 3.29Å; E698-R701 IonicContact OE2-NE 3.94Å; E698-R701 PolarHBondContact OE2-NE 2.9Å; E698-R701 IonicContact OE2-NH1 3.54Å; E698-R701 IonicContact OE2-NH2 3.67Å; E698-R701 PolarHBondContact OE2-NH2 3.37Å; E698-E702 PolarHBondContact O-N 3.23Å
699R70.4Confident74.4Confident112 Ų11249 Ų4942%0.42324%0.239SC..Hα-helixtrans-59.8-45.8175.8-175.6-177.1174.4177.78.7112.5E542 T697 R701 E702 E703E542-R699 IonicContact OE1-CZ 3.04Å; E542-R699 VanDerWaalsContact OE1-CZ 3.32Å; E542-R699 IonicContact OE1-NH1 3Å; E542-R699 PolarHBondContact OE1-NH1 3.34Å; E542-R699 VanDerWaalsContact OE1-NH1 3.14Å; E542-R699 IonicContact OE1-NH2 3.47Å; E542-R699 PolarHBondContact OE1-NH2 3.33Å; E542-R699 IonicContact OE2-CZ 2.7Å; E542-R699 IonicContact OE2-NE 2.71Å; E542-R699 IonicContact OE2-NH1 3.43Å; E542-R699 PolarHBondContact OE2-NH1 2.91Å; E542-R699 VanDerWaalsContact OE2-NH1 3.13Å; E542-R699 IonicContact OE2-NH2 3.57Å; E542-R699 PolarHBondContact OE2-NH2 3.41Å; T697-R699 PolarHBondContact O-N 2.93Å; R699-R701 PolarHBondContact O-N 3.01Å; R699-E702 PolarHBondContact O-N 3.14Å; R699-E703 IonicContact CZ-OE1 2.9Å; R699-E703 IonicContact NE-OE1 3.76Å; R699-E703 PolarHBondContact NE-OE1 3.2Å; R699-E703 IonicContact NH2-OE1 3.8Å; R699-E703 WeakPolarHBondContact O-CG 3.22Å; R699-E703 PolarHBondContact O-N 3.11Å
700M71.2Confident74.5Confident38 Ų3854.9 Ų54.919%0.18727%0.267CS..Hα-helixtrans-61.8-36.9175.9-69.4178.992.700111.1M578 T697 E698 E703 E704M578-M700 HydrophobicContact CE-CE 4.18Å; T697-M700 PolarHBondContact O-N 3.05Å; T697-M700 WeakPolarHBondContact OG1-CG 3.33Å; T697-M700 PolarHBondContact OG1-N 3.46Å; T697-M700 VanDerWaalsContact OG1-N 3.17Å; E698-M700 PolarHBondContact O-N 3.32Å; M700-E703 PolarHBondContact O-N 3.03Å; M700-E704 VanDerWaalsContact O-CG 3.29Å; M700-E704 WeakPolarHBondContact O-CG 3.41Å; M700-E704 PolarHBondContact O-N 3.25Å
701R73.9Confident74.8Confident77 Ų7756.7 Ų56.729%0.29128%0.276SS..Hα-helixtrans-62.3-43.9176.4-169.2-179.568.4177.47.8111.8Y454 T697 E698 R699 E704 N705Y454-R701 HydrophobicContact CE1-CG 4.12Å; Y454-R701 WeakPolarHBondContact OH-CG 3.29Å; T697-R701 PolarHBondContact O-N 3.45Å; E698-R701 VanDerWaalsContact CD-CZ 3.44Å; E698-R701 WeakPolarHBondContact O-CA 3.44Å; E698-R701 VanDerWaalsContact O-CB 3.28Å; E698-R701 WeakPolarHBondContact O-CB 3.01Å; E698-R701 PolarHBondContact O-N 3.16Å; E698-R701 VanDerWaalsContact O-N 3.1Å; E698-R701 IonicContact OE1-CZ 3.14Å; E698-R701 IonicContact OE1-NE 3.13Å; E698-R701 PolarHBondContact OE1-NE 3.11Å; E698-R701 IonicContact OE1-NH2 3.82Å; E698-R701 PolarHBondContact OE1-NH2 3.38Å; E698-R701 IonicContact OE2-CZ 3.29Å; E698-R701 IonicContact OE2-NE 3.94Å; E698-R701 PolarHBondContact OE2-NE 2.9Å; E698-R701 IonicContact OE2-NH1 3.54Å; E698-R701 IonicContact OE2-NH2 3.67Å; E698-R701 PolarHBondContact OE2-NH2 3.37Å; R699-R701 PolarHBondContact O-N 3.01Å; R701-E704 PolarHBondContact O-N 3.39Å; R701-N705 WeakPolarHBondContact O-CB 3.44Å; R701-N705 VanDerWaalsContact O-CG 3.26Å; R701-N705 PolarHBondContact O-N 3.43Å; R701-N705 PolarHBondContact O-ND2 2.88Å
702E75.4Confident75.8Confident83 Ų8355 Ų5539%0.38826%0.257SS..Hα-helixtrans-60.7-44.7174.6-68.9178.5-179.700111.9E698 R699 E704 N705 E706E698-E702 PolarHBondContact O-N 3.23Å; R699-E702 PolarHBondContact O-N 3.14Å; E702-E704 PolarHBondContact O-N 3.23Å; E702-N705 WeakPolarHBondContact O-CB 3.42Å; E702-N705 PolarHBondContact O-N 3.11Å; E702-E706 WeakPolarHBondContact O-CG 3.4Å; E702-E706 PolarHBondContact O-N 3.12Å
703E77.3Confident76.9Confident64 Ų6447 Ų4730%0.29923%0.229SC..Hα-helixtrans-63.2-40.6177.4-71.3171.3-17100112.3R699 M700 N705 E706 G707R699-E703 IonicContact CZ-OE1 2.9Å; R699-E703 IonicContact NE-OE1 3.76Å; R699-E703 PolarHBondContact NE-OE1 3.2Å; R699-E703 IonicContact NH2-OE1 3.8Å; R699-E703 WeakPolarHBondContact O-CG 3.22Å; R699-E703 PolarHBondContact O-N 3.11Å; M700-E703 PolarHBondContact O-N 3.03Å; E703-N705 VanDerWaalsContact C-N 3.33Å; E703-E706 PolarHBondContact O-N 3.31Å; E703-G707 PolarHBondContact O-N 2.94Å
704E79Confident78Confident25 Ų2550.8 Ų50.812%0.11725%0.249CC..Hα-helixtrans-62.5-41.7173.7-68-56160.800111.2R453 M700 R701 E702 G707 I708R453-E704 WeakPolarHBondContact CG-OE2 3.45Å; R453-E704 IonicContact CZ-OE2 2.59Å; R453-E704 IonicContact NE-OE2 3.41Å; R453-E704 PolarHBondContact NE-OE2 3.2Å; R453-E704 IonicContact NH2-OE1 3.05Å; R453-E704 IonicContact NH2-OE2 2.99Å; R453-E704 PolarHBondContact NH2-OE2 3.2Å; M700-E704 VanDerWaalsContact O-CG 3.29Å; M700-E704 WeakPolarHBondContact O-CG 3.41Å; M700-E704 PolarHBondContact O-N 3.25Å; R701-E704 PolarHBondContact O-N 3.39Å; E702-E704 PolarHBondContact O-N 3.23Å; E704-G707 PolarHBondContact O-N 2.75Å; E704-I708 VanDerWaalsContact O-CG1 3.3Å; E704-I708 WeakPolarHBondContact O-CG1 3.41Å; E704-I708 PolarHBondContact O-N 2.8Å
705N81Confident79.2Confident8 Ų852.8 Ų52.84%0.04326%0.256CS..Hα-helixtrans-64.2-44.9176.6-73.4-16.2000112.2L388 Y454 R701 E702 E703 G707 I708 V709L388-N705 HydrophobicContact CD2-CB 3.59Å; Y454-N705 PolarHBondContact OH-OD1 3.26Å; R701-N705 WeakPolarHBondContact O-CB 3.44Å; R701-N705 VanDerWaalsContact O-CG 3.26Å; R701-N705 PolarHBondContact O-N 3.43Å; R701-N705 PolarHBondContact O-ND2 2.88Å; E702-N705 WeakPolarHBondContact O-CB 3.42Å; E702-N705 PolarHBondContact O-N 3.11Å; E703-N705 VanDerWaalsContact C-N 3.33Å; N705-G707 VanDerWaalsContact C-N 3.32Å; N705-G707 PolarHBondContact O-N 2.88Å; N705-I708 PolarHBondContact O-N 2.72Å; N705-V709 WeakPolarHBondContact O-CG2 3.49Å; N705-V709 PolarHBondContact O-N 3.06Å
706E80.8Confident80.4Confident54 Ų5451 Ų5125%0.25225%0.246SC..Hα-helixtrans-61.9-41.1174.7-72.2-176.4178.600111.2P389 K391 E702 E703 I708 V709 Q710P389-E706 HydrophobicContact CG-CG 4.43Å; K391-E706 IonicContact NZ-OE1 3.47Å; E702-E706 WeakPolarHBondContact O-CG 3.4Å; E702-E706 PolarHBondContact O-N 3.12Å; E703-E706 PolarHBondContact O-N 3.31Å; E706-I708 VanDerWaalsContact C-N 3.34Å; E706-I708 PolarHBondContact O-N 2.87Å; E706-V709 PolarHBondContact O-N 2.86Å; E706-Q710 WeakPolarHBondContact O-CG 3.16Å; E706-Q710 PolarHBondContact O-N 2.74Å
707G82.7Confident81.8Confident19 Ų1949 Ų4920%0.19623%0.233CC..Hα-helixtrans-61.8-37.3175.900000113.5E703 E704 N705 L711E703-G707 PolarHBondContact O-N 2.94Å; E704-G707 PolarHBondContact O-N 2.75Å; N705-G707 VanDerWaalsContact C-N 3.32Å; N705-G707 PolarHBondContact O-N 2.88Å; G707-L711 WeakPolarHBondContact O-CB 3.45Å; G707-L711 PolarHBondContact O-N 2.86Å
708I85.3Confident82.9Confident4 Ų451.8 Ų51.82%0.02124%0.243CC..Hα-helixtrans-62.1-49.2173.8-68.8159.9000110.1L388 V450 R453 Y454 E704 N705 E706 Q710 L711 R712L388-I708 HydrophobicContact CD1-CG2 4.42Å; V450-I708 HydrophobicContact CB-CD1 4.42Å; V450-I708 HydrophobicContact CG1-CD1 4.3Å; V450-I708 HydrophobicContact CG2-CD1 4.31Å; V450-I708 HydrophobicContact CG2-CG2 4.34Å; R453-I708 HydrophobicContact CB-CD1 3.94Å; R453-I708 HydrophobicContact CB-CG1 3.81Å; R453-I708 HydrophobicContact CG-CD1 4.05Å; R453-I708 HydrophobicContact CG-CG1 3.74Å; Y454-I708 HydrophobicContact CE2-CD1 4.17Å; E704-I708 VanDerWaalsContact O-CG1 3.3Å; E704-I708 WeakPolarHBondContact O-CG1 3.41Å; E704-I708 PolarHBondContact O-N 2.8Å; N705-I708 PolarHBondContact O-N 2.72Å; E706-I708 VanDerWaalsContact C-N 3.34Å; E706-I708 PolarHBondContact O-N 2.87Å; I708-Q710 PolarHBondContact O-N 3.49Å; I708-L711 PolarHBondContact O-N 2.7Å; I708-R712 HydrophobicContact CG2-CG 4.44Å; I708-R712 WeakPolarHBondContact O-CG 3.41Å; I708-R712 PolarHBondContact O-N 3.03Å
709V84.9Confident84.1Confident12 Ų1247.4 Ų47.47%0.07322%0.223CC..Hα-helixtrans-60.5-46.3-178.9176.10000111.3L388 M390 N705 E706 L711 R712 I713L388-V709 HydrophobicContact CB-CG2 3.72Å; L388-V709 HydrophobicContact CD1-CG2 4.13Å; L388-V709 HydrophobicContact CG-CG2 4.38Å; M390-V709 HydrophobicContact CE-CG1 3.83Å; M390-V709 HydrophobicContact CG-CG1 3.82Å; N705-V709 WeakPolarHBondContact O-CG2 3.49Å; N705-V709 PolarHBondContact O-N 3.06Å; E706-V709 PolarHBondContact O-N 2.86Å; V709-L711 VanDerWaalsContact C-N 3.3Å; V709-L711 PolarHBondContact O-N 3.02Å; V709-R712 PolarHBondContact O-N 2.84Å; V709-I713 HydrophobicContact CG1-CD1 4.16Å; V709-I713 WeakPolarHBondContact O-CG1 3.37Å; V709-I713 PolarHBondContact O-N 3.06Å
710Q85.1Confident85.2Confident124 Ų12442 Ų4258%0.57920%0.203SC*.Hα-helixtrans-60.1-41.7177.1-71.2178.59.400111.8E706 I708 I713 L714E706-Q710 WeakPolarHBondContact O-CG 3.16Å; E706-Q710 PolarHBondContact O-N 2.74Å; I708-Q710 PolarHBondContact O-N 3.49Å; Q710-I713 WeakPolarHBondContact O-CB 3.24Å; Q710-I713 PolarHBondContact O-N 2.98Å; Q710-L714 WeakPolarHBondContact O-CG 3.49Å; Q710-L714 PolarHBondContact O-N 3.27Å
711L86.9Confident86.3Confident52 Ų5241.7 Ų41.727%0.27220%0.201SC..Hα-helixtrans-69.1-37.5179.7-170.853.6000112.2Y490 G707 I708 V709 I713 L714 R715Y490-L711 HydrophobicContact CE1-CD2 4.45Å; Y490-L711 WeakPolarHBondContact OH-CD2 3.31Å; G707-L711 WeakPolarHBondContact O-CB 3.45Å; G707-L711 PolarHBondContact O-N 2.86Å; I708-L711 PolarHBondContact O-N 2.7Å; V709-L711 VanDerWaalsContact C-N 3.3Å; V709-L711 PolarHBondContact O-N 3.02Å; L711-I713 VanDerWaalsContact C-N 3.31Å; L711-I713 PolarHBondContact O-N 3.01Å; L711-L714 PolarHBondContact O-N 2.99Å; L711-R715 HydrophobicContact CD1-CG 4.3Å; L711-R715 HydrophobicContact CG-CG 4.43Å; L711-R715 WeakPolarHBondContact O-CB 3.32Å; L711-R715 VanDerWaalsContact O-CG 3.29Å; L711-R715 WeakPolarHBondContact O-CG 3.28Å; L711-R715 PolarHBondContact O-N 2.92Å
712R90.4Very high87.2Confident7 Ų743.7 Ų43.73%0.02621%0.214CC..Hα-helixtrans-60.2-41.5172.4-71.8-179.3177.9179.1-0112E402 D449 I708 V709 T716 F747 M753E402-R712 IonicContact OE1-CZ 2.72Å; E402-R712 IonicContact OE1-NH1 3.94Å; E402-R712 PolarHBondContact OE1-NH1 2.71Å; E402-R712 IonicContact OE2-CZ 3.32Å; E402-R712 IonicContact OE2-NH1 2.94Å; E402-R712 PolarHBondContact OE2-NH1 2.87Å; E402-R712 IonicContact OE2-NH2 3.93Å; E402-R712 PolarHBondContact OE2-NH2 3.05Å; D449-R712 IonicContact OD1-CZ 3.9Å; D449-R712 IonicContact OD1-NE 2.78Å; D449-R712 IonicContact OD1-NH2 3.84Å; D449-R712 PolarHBondContact OD1-NH2 3.46Å; D449-R712 WeakPolarHBondContact OD2-CG 3.11Å; D449-R712 IonicContact OD2-CZ 2.75Å; D449-R712 IonicContact OD2-NE 3.04Å; D449-R712 PolarHBondContact OD2-NE 2.97Å; D449-R712 IonicContact OD2-NH2 2.88Å; D449-R712 PolarHBondContact OD2-NH2 3.46Å; I708-R712 HydrophobicContact CG2-CG 4.44Å; I708-R712 WeakPolarHBondContact O-CG 3.41Å; I708-R712 PolarHBondContact O-N 3.03Å; V709-R712 PolarHBondContact O-N 2.84Å; R712-T716 VanDerWaalsContact O-CB 3.3Å; R712-T716 WeakPolarHBondContact O-CB 3.34Å; R712-T716 PolarHBondContact O-N 2.86Å; R712-T716 PolarHBondContact O-OG1 3.36Å; R712-F747 HydrophobicContact CB-CD2 4.43Å; R712-F747 HydrophobicContact CB-CE1 4.12Å; R712-F747 HydrophobicContact CB-CE2 3.88Å; R712-F747 HydrophobicContact CB-CZ 3.72Å; R712-F747 HydrophobicContact CG-CD1 3.85Å; R712-F747 HydrophobicContact CG-CD2 3.93Å; R712-F747 HydrophobicContact CG-CE1 3.8Å; R712-F747 HydrophobicContact CG-CE2 3.87Å; R712-F747 HydrophobicContact CG-CG 3.92Å; R712-F747 HydrophobicContact CG-CZ 3.81Å; R712-M753 HydrophobicContact CB-CE 3.99Å; R712-M753 HydrophobicContact CB-SD 4.09Å
713I89.1Confident88.1Confident39 Ų3939.9 Ų39.920%0.220%0.197CC..Hα-helixtrans-58.5-54.3174.9-72.1166.2000110.2M390 V709 Q710 L711 R715 T716 Q717 M753M390-I713 HydrophobicContact CE-CD1 4.27Å; V709-I713 HydrophobicContact CG1-CD1 4.16Å; V709-I713 WeakPolarHBondContact O-CG1 3.37Å; V709-I713 PolarHBondContact O-N 3.06Å; Q710-I713 WeakPolarHBondContact O-CB 3.24Å; Q710-I713 PolarHBondContact O-N 2.98Å; L711-I713 VanDerWaalsContact C-N 3.31Å; L711-I713 PolarHBondContact O-N 3.01Å; I713-R715 PolarHBondContact O-N 3.32Å; I713-T716 WeakPolarHBondContact O-CB 3.49Å; I713-T716 PolarHBondContact O-N 3Å; I713-Q717 WeakPolarHBondContact O-CG 3.26Å; I713-Q717 PolarHBondContact O-N 2.87Å; I713-M753 HydrophobicContact CG1-CE 4.34Å
714L90.6Very high88.9Confident101 Ų10136.9 Ų36.953%0.52918%0.182SC..Hα-helixtrans-60.9-43-179-67.2173000112.2Q710 L711 T716 Q717 E718Q710-L714 WeakPolarHBondContact O-CG 3.49Å; Q710-L714 PolarHBondContact O-N 3.27Å; L711-L714 PolarHBondContact O-N 2.99Å; L714-T716 VanDerWaalsContact C-N 3.34Å; L714-T716 PolarHBondContact O-N 3.41Å; L714-Q717 PolarHBondContact O-N 3.27Å; L714-E718 WeakPolarHBondContact O-CB 3.28Å; L714-E718 PolarHBondContact O-N 3.02Å
715R90.9Very high89.6Confident52 Ų5241 Ų4120%0.19620%0.2CC..Hα-helixtrans-65.6-36.4177.1-71-59.2-168.8-1724.8112.5D489 L711 I713 E718 A719 L743 F747D489-R715 IonicContact OD2-CZ 3.78Å; D489-R715 IonicContact OD2-NH2 2.62Å; D489-R715 PolarHBondContact OD2-NH2 2.92Å; L711-R715 HydrophobicContact CD1-CG 4.3Å; L711-R715 HydrophobicContact CG-CG 4.43Å; L711-R715 WeakPolarHBondContact O-CB 3.32Å; L711-R715 VanDerWaalsContact O-CG 3.29Å; L711-R715 WeakPolarHBondContact O-CG 3.28Å; L711-R715 PolarHBondContact O-N 2.92Å; I713-R715 PolarHBondContact O-N 3.32Å; R715-E718 WeakPolarHBondContact CD-OE2 3.44Å; R715-E718 IonicContact CZ-OE2 3.89Å; R715-E718 IonicContact NE-OE2 2.74Å; R715-E718 IonicContact NH1-OE1 3.64Å; R715-E718 IonicContact NH1-OE2 2.74Å; R715-E718 PolarHBondContact NH1-OE2 3.42Å; R715-A719 VanDerWaalsContact O-CB 3.26Å; R715-A719 WeakPolarHBondContact O-CB 3.45Å; R715-A719 PolarHBondContact O-N 2.93Å; R715-L743 HydrophobicContact CB-CD2 4.29Å; R715-F747 HydrophobicContact CB-CE1 4.24Å
716T92.8Very high90.1Very high0 Ų046.7 Ų46.70%023%0.228CC..Hα-helixtrans-65-46175-58.60000110.7R712 I713 L714 A719 I720 L739 Q757R712-T716 VanDerWaalsContact O-CB 3.3Å; R712-T716 WeakPolarHBondContact O-CB 3.34Å; R712-T716 PolarHBondContact O-N 2.86Å; R712-T716 PolarHBondContact O-OG1 3.36Å; I713-T716 WeakPolarHBondContact O-CB 3.49Å; I713-T716 PolarHBondContact O-N 3Å; L714-T716 VanDerWaalsContact C-N 3.34Å; L714-T716 PolarHBondContact O-N 3.41Å; T716-A719 PolarHBondContact O-N 2.88Å; T716-I720 HydrophobicContact CG2-CD1 3.84Å; T716-I720 WeakPolarHBondContact O-CD1 3.43Å; T716-I720 VanDerWaalsContact O-CG1 3.22Å; T716-I720 WeakPolarHBondContact O-CG1 3.32Å; T716-I720 PolarHBondContact O-N 3.43Å; T716-L739 HydrophobicContact CG2-CD2 4.16Å; T716-Q757 HydrophobicContact CG2-CB 4.1Å; T716-Q757 HydrophobicContact CG2-CG 3.95Å
717Q92.4Very high90.7Very high23 Ų2350.6 Ų50.611%0.10724%0.24CC..Hα-helixtrans-60.6-49.1176.2-68.3171.6-6.500111.6I713 L714 A719 I720 I721 Q757 W760I713-Q717 WeakPolarHBondContact O-CG 3.26Å; I713-Q717 PolarHBondContact O-N 2.87Å; L714-Q717 PolarHBondContact O-N 3.27Å; Q717-A719 PolarHBondContact O-N 2.8Å; Q717-I720 PolarHBondContact O-N 3.27Å; Q717-I721 VanDerWaalsContact O-CG1 3.29Å; Q717-I721 WeakPolarHBondContact O-CG1 3.4Å; Q717-I721 PolarHBondContact O-N 2.98Å; Q717-Q757 HydrophobicContact CG-CB 4.24Å; Q717-Q757 HydrophobicContact CG-CG 4.19Å; Q717-W760 HydrophobicContact CG-CE3 4.29Å; Q717-W760 HydrophobicContact CG-CZ3 4.49Å
718E92.6Very high91.1Very high97 Ų9754.8 Ų54.845%0.45325%0.253SS..Hα-helixtrans-56.7-48.8177.9-178.8-175.2-164.200111.7L714 R715 I721 Q722L714-E718 WeakPolarHBondContact O-CB 3.28Å; L714-E718 PolarHBondContact O-N 3.02Å; R715-E718 WeakPolarHBondContact CD-OE2 3.44Å; R715-E718 IonicContact CZ-OE2 3.89Å; R715-E718 IonicContact NE-OE2 2.74Å; R715-E718 IonicContact NH1-OE1 3.64Å; R715-E718 IonicContact NH1-OE2 2.74Å; R715-E718 PolarHBondContact NH1-OE2 3.42Å; E718-I721 PolarHBondContact O-N 2.99Å; E718-Q722 WeakPolarHBondContact O-CB 3.44Å; E718-Q722 PolarHBondContact O-N 3.4Å
719A93.7Very high91.5Very high4 Ų461.5 Ų61.53%0.03328%0.278CS..Hα-helixtrans-65.2-41.5-179.100000112.2R715 T716 Q717 Q722 I723 L739 I742 L743R715-A719 VanDerWaalsContact O-CB 3.26Å; R715-A719 WeakPolarHBondContact O-CB 3.45Å; R715-A719 PolarHBondContact O-N 2.93Å; T716-A719 PolarHBondContact O-N 2.88Å; Q717-A719 PolarHBondContact O-N 2.8Å; A719-Q722 PolarHBondContact O-N 3.29Å; A719-I723 WeakPolarHBondContact O-CG1 3.37Å; A719-I723 PolarHBondContact O-N 3.28Å; A719-L739 HydrophobicContact CB-CD1 3.49Å; A719-L739 VanDerWaalsContact CB-CD1 3.49Å; A719-I742 HydrophobicContact CB-CG2 4.21Å; A719-L743 HydrophobicContact CB-CD2 4.3Å; A719-L743 HydrophobicContact CB-CG 4.43Å
720I93.8Very high91.9Very high0 Ų061.3 Ų61.30%028%0.277CS..Hα-helixtrans-61-47.1174.6-67.3165.2000110.2T716 Q717 Q722 I723 M724 L735 L739 Q757 I758 L761T716-I720 HydrophobicContact CG2-CD1 3.84Å; T716-I720 WeakPolarHBondContact O-CD1 3.43Å; T716-I720 VanDerWaalsContact O-CG1 3.22Å; T716-I720 WeakPolarHBondContact O-CG1 3.32Å; T716-I720 PolarHBondContact O-N 3.43Å; Q717-I720 PolarHBondContact O-N 3.27Å; I720-Q722 VanDerWaalsContact C-N 3.3Å; I720-Q722 PolarHBondContact O-N 3.09Å; I720-I723 PolarHBondContact O-N 3.46Å; I720-M724 HydrophobicContact CG2-CG 4.08Å; I720-M724 VanDerWaalsContact O-CB 3.31Å; I720-M724 WeakPolarHBondContact O-CB 3.44Å; I720-M724 WeakPolarHBondContact O-CG 3.32Å; I720-M724 PolarHBondContact O-N 3.15Å; I720-L735 HydrophobicContact CG2-CD1 4.37Å; I720-L735 HydrophobicContact CG2-CD2 4.34Å; I720-L739 HydrophobicContact CD1-CD2 4.28Å; I720-L739 HydrophobicContact CG1-CD1 4.1Å; I720-L739 HydrophobicContact CG1-CD2 4Å; I720-Q757 HydrophobicContact CD1-CB 4.2Å; I720-I758 HydrophobicContact CD1-CG1 4.09Å; I720-L761 HydrophobicContact CB-CD1 3.72Å; I720-L761 HydrophobicContact CD1-CD1 4.1Å; I720-L761 HydrophobicContact CG2-CD1 3.4Å; I720-L761 VanDerWaalsContact CG2-CD1 3.4Å
721I93.6Very high92.4Very high30 Ų3057 Ų5715%0.15426%0.26CS..Hα-helixtrans-60.2-41.9178.3-68.5166.1000110.8Q717 E718 M724 K725 L761 Y766Q717-I721 VanDerWaalsContact O-CG1 3.29Å; Q717-I721 WeakPolarHBondContact O-CG1 3.4Å; Q717-I721 PolarHBondContact O-N 2.98Å; E718-I721 PolarHBondContact O-N 2.99Å; I721-M724 PolarHBondContact O-N 3.08Å; I721-K725 HydrophobicContact CG2-CD 3.94Å; I721-K725 HydrophobicContact CG2-CG 4.31Å; I721-K725 WeakPolarHBondContact O-CB 3.47Å; I721-K725 VanDerWaalsContact O-CG 3.28Å; I721-K725 WeakPolarHBondContact O-CG 3.47Å; I721-K725 PolarHBondContact O-N 3.3Å; I721-L761 HydrophobicContact CD1-CD2 3.69Å; I721-L761 HydrophobicContact CG1-CD1 4.38Å; I721-L761 HydrophobicContact CG1-CD2 3.75Å; I721-Y766 HydrophobicContact CD1-CD1 4.26Å; I721-Y766 HydrophobicContact CD1-CE1 4.46Å; I721-Y766 HydrophobicContact CD1-CG 4.38Å
722Q93.6Very high92.6Very high119 Ų11956.1 Ų56.156%0.55626%0.256SS*.Hα-helixtrans-62.6-46.9178.8-174.6178.8-800112.1E718 A719 I720 K725 M726E718-Q722 WeakPolarHBondContact O-CB 3.44Å; E718-Q722 PolarHBondContact O-N 3.4Å; A719-Q722 PolarHBondContact O-N 3.29Å; I720-Q722 VanDerWaalsContact C-N 3.3Å; I720-Q722 PolarHBondContact O-N 3.09Å; Q722-K725 PolarHBondContact O-N 3.18Å; Q722-M726 PolarHBondContact O-N 3.5Å
723I93.8Very high92.7Very high4 Ų459 Ų592%0.02128%0.281CS..Hα-helixtrans-60.5-47.9176.2-67.6163.4000110.2A719 I720 K725 M726 R727 I730 L735 E738 L739 I742A719-I723 WeakPolarHBondContact O-CG1 3.37Å; A719-I723 PolarHBondContact O-N 3.28Å; I720-I723 PolarHBondContact O-N 3.46Å; I723-K725 VanDerWaalsContact C-N 3.35Å; I723-K725 PolarHBondContact O-N 3.17Å; I723-M726 PolarHBondContact O-N 3.26Å; I723-M726 VanDerWaalsContact O-N 3.11Å; I723-R727 HydrophobicContact CG2-CG 4.31Å; I723-R727 PolarHBondContact O-N 3.38Å; I723-I730 HydrophobicContact CG2-CD1 3.71Å; I723-L735 HydrophobicContact CB-CD1 4.07Å; I723-L735 HydrophobicContact CD1-CD1 4Å; I723-L735 HydrophobicContact CG2-CD1 3.7Å; I723-E738 HydrophobicContact CD1-CB 3.81Å; I723-E738 HydrophobicContact CG1-CB 4.29Å; I723-E738 WeakPolarHBondContact CG2-OE2 3.45Å; I723-L739 HydrophobicContact CD1-CB 4.13Å; I723-I742 HydrophobicContact CD1-CD1 3.83Å; I723-I742 HydrophobicContact CG1-CD1 3.7Å
724M93.7Very high92.9Very high0 Ų062.5 Ų62.50%030%0.296CS..Hα-helixtrans-64.4-38-178.1-70.7-65.6-60.100112.4I720 I721 M726 K728 I730 I767 F777 Y779I720-M724 HydrophobicContact CG2-CG 4.08Å; I720-M724 VanDerWaalsContact O-CB 3.31Å; I720-M724 WeakPolarHBondContact O-CB 3.44Å; I720-M724 WeakPolarHBondContact O-CG 3.32Å; I720-M724 PolarHBondContact O-N 3.15Å; I721-M724 PolarHBondContact O-N 3.08Å; M724-M726 VanDerWaalsContact C-N 3.3Å; M724-M726 PolarHBondContact O-N 3.06Å; M724-K728 VanDerWaalsContact O-CA 3.24Å; M724-K728 WeakPolarHBondContact O-CA 3.29Å; M724-K728 PolarHBondContact O-N 3.43Å; M724-I730 HydrophobicContact CE-CG2 4.48Å; M724-I730 HydrophobicContact SD-CG2 3.34Å; M724-I730 WeakPolarHBondContact SD-CG2 2.98Å; M724-I767 HydrophobicContact CB-CG2 4.07Å; M724-I767 HydrophobicContact CE-CB 4.11Å; M724-I767 HydrophobicContact CE-CG2 3.62Å; M724-I767 HydrophobicContact CG-CG2 3.77Å; M724-I767 HydrophobicContact SD-CG2 4.36Å; M724-F777 HydrophobicContact CE-CB 3.65Å; M724-F777 HydrophobicContact SD-CB 4.02Å; M724-Y779 HydrophobicContact CB-CD2 3.77Å; M724-Y779 HydrophobicContact CB-CG 4.38Å; M724-Y779 WeakPolarHBondContact O-CB 3.32Å
725K93.4Very high93Very high111 Ų11157.7 Ų57.748%0.48327%0.271SS..Hα-helixtrans-60.5-39.7172.7-81.6175.5176.81790112.2I721 Q722 I723 K728 Y779I721-K725 HydrophobicContact CG2-CD 3.94Å; I721-K725 HydrophobicContact CG2-CG 4.31Å; I721-K725 WeakPolarHBondContact O-CB 3.47Å; I721-K725 VanDerWaalsContact O-CG 3.28Å; I721-K725 WeakPolarHBondContact O-CG 3.47Å; I721-K725 PolarHBondContact O-N 3.3Å; Q722-K725 PolarHBondContact O-N 3.18Å; I723-K725 VanDerWaalsContact C-N 3.35Å; I723-K725 PolarHBondContact O-N 3.17Å; K725-K728 VanDerWaalsContact O-CE 3.3Å; K725-K728 WeakPolarHBondContact O-CE 3.25Å; K725-Y779 WeakPolarHBondContact CE-OH 3.49Å; K725-Y779 HydrophobicContact CG-CD2 4.35Å; K725-Y779 HydrophobicContact CG-CE1 3.85Å; K725-Y779 HydrophobicContact CG-CE2 3.63Å; K725-Y779 WeakPolarHBondContact CG-OH 3.42Å
726M92.6Very high93Very high129 Ų12957.4 Ų57.464%0.63527%0.272SS*.Hα-helixtrans-76.5-46.9-177.6-173.3178.273.600112.6Q722 I723 M724Q722-M726 PolarHBondContact O-N 3.5Å; I723-M726 PolarHBondContact O-N 3.26Å; I723-M726 VanDerWaalsContact O-N 3.11Å; M724-M726 VanDerWaalsContact C-N 3.3Å; M724-M726 PolarHBondContact O-N 3.06Å
727R92.1Very high93Very high135 Ų13561.5 Ų61.551%0.50930%0.297SS..Hα-helixtrans-89.3-24.1-173.3-62.3-65.5-164.4-173.91.6113.7I723 R729 I730 E738I723-R727 HydrophobicContact CG2-CG 4.31Å; I723-R727 PolarHBondContact O-N 3.38Å; R727-R729 PolarHBondContact O-N 2.95Å; R727-I730 HydrophobicContact CB-CB 4.42Å; R727-I730 HydrophobicContact CG-CD1 4.27Å; R727-E738 IonicContact CZ-OE1 2.63Å; R727-E738 VanDerWaalsContact CZ-OE1 3.29Å; R727-E738 IonicContact NE-OE1 3.73Å; R727-E738 PolarHBondContact NE-OE1 3.09Å; R727-E738 IonicContact NE-OE2 3.12Å; R727-E738 IonicContact NH2-OE1 3.99Å; R727-E738 PolarHBondContact NH2-OE1 3.17Å
728K92.1Very high93.1Very high107 Ų10762.1 Ų62.147%0.46530%0.3SS..SBendtrans60.5-35.9-175.4-60.3-65-171.8173.70116M724 K725 I778 Y779M724-K728 VanDerWaalsContact O-CA 3.24Å; M724-K728 WeakPolarHBondContact O-CA 3.29Å; M724-K728 PolarHBondContact O-N 3.43Å; K725-K728 VanDerWaalsContact O-CE 3.3Å; K725-K728 WeakPolarHBondContact O-CE 3.25Å; K728-I778 CarbonylContact O-C 3.58Å; K728-I778 WeakPolarHBondContact O-CA 3.18Å; K728-Y779 HydrophobicContact CD-CD1 3.97Å; K728-Y779 HydrophobicContact CD-CG 4.47Å; K728-Y779 PolarHBondContact O-N 3.42Å
729R92.9Very high93.1Very high146 Ų14657.5 Ų57.555%0.55128%0.279SS*.EExtended strand (participates in β ladder)trans-138.1129.3172.7-171.5175.2-174.3-148.51.6109.1R727 D770 T776 F777 I778R727-R729 PolarHBondContact O-N 2.95Å; R729-D770 IonicContact CZ-OD2 3.73Å; R729-D770 IonicContact NE-OD2 2.83Å; R729-D770 PolarHBondContact NE-OD2 3.41Å; R729-D770 IonicContact NH2-OD2 3.21Å; R729-D770 PolarHBondContact NH2-OD2 3.02Å; R729-T776 HydrophobicContact CG-CG2 3.62Å; R729-F777 VanDerWaalsContact CA-O 3.27Å; R729-F777 WeakPolarHBondContact CA-O 3.31Å; R729-I778 HydrophobicContact CG-CG1 4.2Å
730I94.6Very high93Very high8 Ų859.6 Ų59.64%0.04129%0.291CS..EExtended strand (participates in β ladder)trans-151.1146.2-177.3-164.8171.9000111.1I723 M724 R727 Q734 L735 F777I723-I730 HydrophobicContact CG2-CD1 3.71Å; M724-I730 HydrophobicContact CE-CG2 4.48Å; M724-I730 HydrophobicContact SD-CG2 3.34Å; M724-I730 WeakPolarHBondContact SD-CG2 2.98Å; R727-I730 HydrophobicContact CB-CB 4.42Å; R727-I730 HydrophobicContact CG-CD1 4.27Å; I730-Q734 HydrophobicContact CD1-CB 3.91Å; I730-Q734 HydrophobicContact CG1-CB 3.62Å; I730-L735 HydrophobicContact CD1-CB 4.13Å; I730-L735 HydrophobicContact CG1-CB 4.44Å; I730-L735 HydrophobicContact CG2-CB 4.09Å; I730-L735 HydrophobicContact CG2-CD1 4.39Å; I730-F777 PolarHBondContact N-O 3.44Å; I730-F777 PolarHBondContact O-N 3.01Å
731S94.8Very high92.8Very high33 Ų3365.1 Ų65.123%0.23132%0.317CS..EExtended strand (participates in β ladder)trans-77.115717267.10000111.8A733 Q734 L735 N775S731-A733 VanDerWaalsContact C-N 3.3Å; S731-A733 PolarHBondContact O-N 2.98Å; S731-Q734 PolarHBondContact O-N 3.09Å; S731-Q734 WeakPolarHBondContact OG-CB 3.36Å; S731-Q734 VanDerWaalsContact OG-CD 3.25Å; S731-Q734 VanDerWaalsContact OG-CG 3.26Å; S731-Q734 WeakPolarHBondContact OG-CG 3.25Å; S731-Q734 PolarHBondContact OG-N 3.32Å; S731-Q734 PolarHBondContact OG-OE1 2.92Å; S731-L735 WeakPolarHBondContact O-CB 3.22Å; S731-L735 PolarHBondContact O-N 2.97Å; S731-N775 CarbonylContact C-O 3.56Å; S731-N775 WeakPolarHBondContact CA-O 3.17Å
732N91.6Very high92.6Very high34 Ų3467 Ų6718%0.18233%0.326CS..Hα-helixtrans-58.9-41.1178.7-170.4-65.1000112.2L735 Q736 N775 F777N732-L735 PolarHBondContact O-N 3.14Å; N732-Q736 WeakPolarHBondContact O-CG 3.4Å; N732-Q736 PolarHBondContact O-N 2.9Å; N732-Q736 PolarHBondContact OD1-NE2 2.81Å; N732-N775 WeakPolarHBondContact CB-O 3.48Å; N732-N775 PolarHBondContact N-O 3.35Å; N732-F777 HydrophobicContact CB-CE2 3.81Å; N732-F777 HydrophobicContact CB-CZ 4.38Å; N732-F777 WeakPolarHBondContact ND2-CE2 3.37Å; N732-F777 WeakPolarHBondContact ND2-CZ 3.29Å
733A92.1Very high92.4Very high67 Ų6761.4 Ų61.455%0.55430%0.3SS*.Hα-helixtrans-63.3-47.417800000111.8S731 Q736 T737S731-A733 VanDerWaalsContact C-N 3.3Å; S731-A733 PolarHBondContact O-N 2.98Å; A733-Q736 PolarHBondContact O-N 3.29Å; A733-T737 PolarHBondContact O-N 2.72Å; A733-T737 PolarHBondContact O-OG1 2.92Å
734Q92.8Very high91.9Very high112 Ų11266.5 Ų66.552%0.52332%0.322SS..Hα-helixtrans-64.6-41.4177.6-72.3167.3-34.900111.9I730 S731 Q736 T737 E738I730-Q734 HydrophobicContact CD1-CB 3.91Å; I730-Q734 HydrophobicContact CG1-CB 3.62Å; S731-Q734 PolarHBondContact O-N 3.09Å; S731-Q734 WeakPolarHBondContact OG-CB 3.36Å; S731-Q734 VanDerWaalsContact OG-CD 3.25Å; S731-Q734 VanDerWaalsContact OG-CG 3.26Å; S731-Q734 WeakPolarHBondContact OG-CG 3.25Å; S731-Q734 PolarHBondContact OG-N 3.32Å; S731-Q734 PolarHBondContact OG-OE1 2.92Å; Q734-Q736 VanDerWaalsContact C-N 3.35Å; Q734-Q736 PolarHBondContact O-N 3.29Å; Q734-T737 PolarHBondContact O-N 3.1Å; Q734-E738 PolarHBondContact O-N 3.47Å
735L92.8Very high91.4Very high1 Ų170.5 Ų70.51%0.00534%0.344CS..Hα-helixtrans-59.9-45.1176.2179.763.9000111.2I720 I723 I730 S731 N732 L739 I758 F777I720-L735 HydrophobicContact CG2-CD1 4.37Å; I720-L735 HydrophobicContact CG2-CD2 4.34Å; I723-L735 HydrophobicContact CB-CD1 4.07Å; I723-L735 HydrophobicContact CD1-CD1 4Å; I723-L735 HydrophobicContact CG2-CD1 3.7Å; I730-L735 HydrophobicContact CD1-CB 4.13Å; I730-L735 HydrophobicContact CG1-CB 4.44Å; I730-L735 HydrophobicContact CG2-CB 4.09Å; I730-L735 HydrophobicContact CG2-CD1 4.39Å; S731-L735 WeakPolarHBondContact O-CB 3.22Å; S731-L735 PolarHBondContact O-N 2.97Å; N732-L735 PolarHBondContact O-N 3.14Å; L735-L739 WeakPolarHBondContact O-CB 3.39Å; L735-L739 PolarHBondContact O-N 3.46Å; L735-I758 HydrophobicContact CD2-CD1 3.92Å; L735-I758 HydrophobicContact CD2-CG1 4.34Å; L735-F777 HydrophobicContact CD2-CD2 3.8Å; L735-F777 HydrophobicContact CD2-CE2 4Å
736Q92.1Very high91Very high45 Ų4566.7 Ų66.721%0.2133%0.328CS..Hα-helixtrans-62.3-42.7176.9-74.6-173.934.100111.9N732 A733 Q734 L739 V740 I754N732-Q736 WeakPolarHBondContact O-CG 3.4Å; N732-Q736 PolarHBondContact O-N 2.9Å; N732-Q736 PolarHBondContact OD1-NE2 2.81Å; A733-Q736 PolarHBondContact O-N 3.29Å; Q734-Q736 VanDerWaalsContact C-N 3.35Å; Q734-Q736 PolarHBondContact O-N 3.29Å; Q736-L739 PolarHBondContact O-N 2.79Å; Q736-V740 WeakPolarHBondContact O-CB 3.28Å; Q736-V740 VanDerWaalsContact O-CG2 3.27Å; Q736-V740 WeakPolarHBondContact O-CG2 3Å; Q736-V740 PolarHBondContact O-N 3Å; Q736-I754 HydrophobicContact CG-CD1 4.44Å; Q736-I754 HydrophobicContact CG-CG2 4.38Å
737T92.9Very high90.8Very high86 Ų8660.7 Ų60.753%0.52830%0.298SS..Hα-helixtrans-63.2-51.3178.3-60.90000111.7A733 Q734 L739 V740 E741A733-T737 PolarHBondContact O-N 2.72Å; A733-T737 PolarHBondContact O-OG1 2.92Å; Q734-T737 PolarHBondContact O-N 3.1Å; T737-L739 VanDerWaalsContact C-N 3.31Å; T737-L739 PolarHBondContact O-N 2.93Å; T737-V740 PolarHBondContact O-N 3.48Å; T737-E741 PolarHBondContact O-N 2.62Å
738E93.4Very high90.5Very high37 Ų3758.1 Ų58.117%0.17329%0.294CS..Hα-helixtrans-62.9-38.8178.4-70.2-167.5-171.100111.4I723 R727 Q734 E741 I742I723-E738 HydrophobicContact CD1-CB 3.81Å; I723-E738 HydrophobicContact CG1-CB 4.29Å; I723-E738 WeakPolarHBondContact CG2-OE2 3.45Å; R727-E738 IonicContact CZ-OE1 2.63Å; R727-E738 VanDerWaalsContact CZ-OE1 3.29Å; R727-E738 IonicContact NE-OE1 3.73Å; R727-E738 PolarHBondContact NE-OE1 3.09Å; R727-E738 IonicContact NE-OE2 3.12Å; R727-E738 IonicContact NH2-OE1 3.99Å; R727-E738 PolarHBondContact NH2-OE1 3.17Å; Q734-E738 PolarHBondContact O-N 3.47Å; E738-E741 PolarHBondContact O-N 3.32Å; E738-I742 WeakPolarHBondContact O-CG1 3.44Å; E738-I742 PolarHBondContact O-N 3.25Å
739L93.3Very high90.1Very high0 Ų053.5 Ų53.50%028%0.275CS..Hα-helixtrans-63.1-44.5177.8-179.563.1000112.2T716 A719 I720 I723 L735 Q736 T737 E741 I742 L743 P749 I754T716-L739 HydrophobicContact CG2-CD2 4.16Å; A719-L739 HydrophobicContact CB-CD1 3.49Å; A719-L739 VanDerWaalsContact CB-CD1 3.49Å; I720-L739 HydrophobicContact CD1-CD2 4.28Å; I720-L739 HydrophobicContact CG1-CD1 4.1Å; I720-L739 HydrophobicContact CG1-CD2 4Å; I723-L739 HydrophobicContact CD1-CB 4.13Å; L735-L739 WeakPolarHBondContact O-CB 3.39Å; L735-L739 PolarHBondContact O-N 3.46Å; Q736-L739 PolarHBondContact O-N 2.79Å; T737-L739 VanDerWaalsContact C-N 3.31Å; T737-L739 PolarHBondContact O-N 2.93Å; L739-E741 VanDerWaalsContact C-N 3.31Å; L739-E741 PolarHBondContact O-N 3.29Å; L739-I742 PolarHBondContact O-N 2.88Å; L739-L743 HydrophobicContact CD1-CD1 3.54Å; L739-L743 HydrophobicContact CD1-CG 4.14Å; L739-L743 HydrophobicContact CG-CD1 4Å; L739-L743 WeakPolarHBondContact O-CB 3.33Å; L739-L743 WeakPolarHBondContact O-CG 3.04Å; L739-L743 PolarHBondContact O-N 3.13Å; L739-P749 HydrophobicContact CG-CG 4.45Å; L739-I754 HydrophobicContact CD2-CB 4.41Å; L739-I754 HydrophobicContact CD2-CD1 3.87Å; L739-I754 HydrophobicContact CD2-CG1 3.72Å; L739-I754 HydrophobicContact CD2-CG2 3.9Å
740V90.9Very high89.7Confident48 Ų4849.4 Ų49.429%0.29126%0.262SS..Hα-helixtrans-63.4-39.8175.5169.80000110.3Q736 T737 I742 L743 K744 L748 P749Q736-V740 WeakPolarHBondContact O-CB 3.28Å; Q736-V740 VanDerWaalsContact O-CG2 3.27Å; Q736-V740 WeakPolarHBondContact O-CG2 3Å; Q736-V740 PolarHBondContact O-N 3Å; T737-V740 PolarHBondContact O-N 3.48Å; V740-I742 PolarHBondContact O-N 3.28Å; V740-L743 PolarHBondContact O-N 3.04Å; V740-K744 WeakPolarHBondContact O-CA 3.46Å; V740-K744 WeakPolarHBondContact O-CB 3.3Å; V740-K744 PolarHBondContact O-N 2.97Å; V740-L748 HydrophobicContact CG1-CD1 3.88Å; V740-P749 HydrophobicContact CG2-CG 3.95Å
741E90.1Very high89.3Confident116 Ų11656.1 Ų56.154%0.54229%0.291SS..Hα-helixtrans-64.2-37178.1-75.4-168.2158.800114T737 E738 L739 K744T737-E741 PolarHBondContact O-N 2.62Å; E738-E741 PolarHBondContact O-N 3.32Å; L739-E741 VanDerWaalsContact C-N 3.31Å; L739-E741 PolarHBondContact O-N 3.29Å; E741-K744 WeakPolarHBondContact O-CE 3.43Å; E741-K744 WeakPolarHBondContact O-CG 3.32Å
742I88.6Confident88.9Confident69 Ų6959.5 Ų59.535%0.35430%0.302SS..Hα-helixtrans-70.3-43175.7-66.3174.9000110.7A719 I723 E738 L739 V740A719-I742 HydrophobicContact CB-CG2 4.21Å; I723-I742 HydrophobicContact CD1-CD1 3.83Å; I723-I742 HydrophobicContact CG1-CD1 3.7Å; E738-I742 WeakPolarHBondContact O-CG1 3.44Å; E738-I742 PolarHBondContact O-N 3.25Å; L739-I742 PolarHBondContact O-N 2.88Å; V740-I742 PolarHBondContact O-N 3.28Å
743L89Confident88.6Confident2 Ų258.5 Ų58.51%0.0130%0.296CS..Hα-helixtrans-89.8-16.8-171.2-64178.3000114.5R715 A719 L739 V740 N745 M746 F747 P749R715-L743 HydrophobicContact CB-CD2 4.29Å; A719-L743 HydrophobicContact CB-CD2 4.3Å; A719-L743 HydrophobicContact CB-CG 4.43Å; L739-L743 HydrophobicContact CD1-CD1 3.54Å; L739-L743 HydrophobicContact CD1-CG 4.14Å; L739-L743 HydrophobicContact CG-CD1 4Å; L739-L743 WeakPolarHBondContact O-CB 3.33Å; L739-L743 WeakPolarHBondContact O-CG 3.04Å; L739-L743 PolarHBondContact O-N 3.13Å; V740-L743 PolarHBondContact O-N 3.04Å; L743-N745 PolarHBondContact O-N 2.84Å; L743-M746 HydrophobicContact CD2-CE 4.38Å; L743-M746 WeakPolarHBondContact O-CA 3.48Å; L743-M746 PolarHBondContact O-N 3.39Å; L743-F747 CarbonylContact C-O 3.55Å; L743-F747 VanDerWaalsContact C-O 3.31Å; L743-F747 HydrophobicContact CD1-CE1 4.36Å; L743-F747 HydrophobicContact CD1-CE2 4.28Å; L743-F747 HydrophobicContact CD1-CZ 3.79Å; L743-F747 HydrophobicContact CD2-CE1 4.14Å; L743-F747 HydrophobicContact CD2-CZ 4.35Å; L743-F747 HydrophobicContact CG-CZ 4.49Å; L743-F747 PolarHBondContact O-N 3.29Å; L743-P749 HydrophobicContact CB-CG 4.44Å; L743-P749 HydrophobicContact CD1-CB 4.14Å; L743-P749 HydrophobicContact CD1-CG 4.06Å
744K84.6Confident88.5Confident110 Ų11055.4 Ų55.448%0.47827%0.27SS..THydrogen-bonded Turntrans-54.1-24.8-173.867.2-172.9174.6-169.20115.7V740 E741 M746V740-K744 WeakPolarHBondContact O-CA 3.46Å; V740-K744 WeakPolarHBondContact O-CB 3.3Å; V740-K744 PolarHBondContact O-N 2.97Å; E741-K744 WeakPolarHBondContact O-CE 3.43Å; E741-K744 WeakPolarHBondContact O-CG 3.32Å; K744-M746 VanDerWaalsContact C-N 3.33Å
745N82.6Confident88.4Confident84 Ų8456.2 Ų56.245%0.44927%0.272SS..THydrogen-bonded Turntrans-82.9-11.8178-69-22000112.9L743L743-N745 PolarHBondContact O-N 2.84Å
746M84.7Confident88.2Confident31 Ų3158.7 Ų58.715%0.15328%0.284CS..THydrogen-bonded Turntrans-106.5-58.7175.4-58.4-169.2-129.700111.2K448 D449 P487 L743 K744K448-M746 PolarHBondContact N-O 3.24Å; D449-M746 PolarHBondContact N-O 3.46Å; P487-M746 HydrophobicContact CB-CG 4.46Å; P487-M746 HydrophobicContact CG-CG 3.61Å; P487-M746 HydrophobicContact CG-SD 4.42Å; L743-M746 HydrophobicContact CD2-CE 4.38Å; L743-M746 WeakPolarHBondContact O-CA 3.48Å; L743-M746 PolarHBondContact O-N 3.39Å; K744-M746 VanDerWaalsContact C-N 3.33Å
747F88.1Confident88.2Confident4 Ų457.2 Ų57.22%0.01828%0.277CS..  trans-160161.8-177.766.5-83.5000110.6R712 R715 L743 P749 M753R712-F747 HydrophobicContact CB-CD2 4.43Å; R712-F747 HydrophobicContact CB-CE1 4.12Å; R712-F747 HydrophobicContact CB-CE2 3.88Å; R712-F747 HydrophobicContact CB-CZ 3.72Å; R712-F747 HydrophobicContact CG-CD1 3.85Å; R712-F747 HydrophobicContact CG-CD2 3.93Å; R712-F747 HydrophobicContact CG-CE1 3.8Å; R712-F747 HydrophobicContact CG-CE2 3.87Å; R712-F747 HydrophobicContact CG-CG 3.92Å; R712-F747 HydrophobicContact CG-CZ 3.81Å; R715-F747 HydrophobicContact CB-CE1 4.24Å; L743-F747 CarbonylContact C-O 3.55Å; L743-F747 VanDerWaalsContact C-O 3.31Å; L743-F747 HydrophobicContact CD1-CE1 4.36Å; L743-F747 HydrophobicContact CD1-CE2 4.28Å; L743-F747 HydrophobicContact CD1-CZ 3.79Å; L743-F747 HydrophobicContact CD2-CE1 4.14Å; L743-F747 HydrophobicContact CD2-CZ 4.35Å; L743-F747 HydrophobicContact CG-CZ 4.49Å; L743-F747 PolarHBondContact O-N 3.29Å; F747-P749 HydrophobicContact CD2-CB 4.45Å; F747-P749 HydrophobicContact CE2-CB 3.89Å; F747-P749 WeakPolarHBondContact O-CD 3.48Å; F747-M753 HydrophobicContact CE2-SD 4.43Å
748L85.7Confident88.2Confident81 Ų8153.4 Ų53.442%0.42425%0.253SS..  trans-90.8111.8172.1-170.967.8000109.9N447 V740 Q750N447-L748 PolarHBondContact OD1-N 3.24Å; V740-L748 HydrophobicContact CG1-CD1 3.88Å; L748-Q750 PolarHBondContact O-N 3.3Å
749P85.4Confident88.1Confident9 Ų956.3 Ų56.36%0.05827%0.266CS..  trans-67.7128.1-177.727.8-35.4000111.1L739 V740 L743 F747 I754L739-P749 HydrophobicContact CG-CG 4.45Å; V740-P749 HydrophobicContact CG2-CG 3.95Å; L743-P749 HydrophobicContact CB-CG 4.44Å; L743-P749 HydrophobicContact CD1-CB 4.14Å; L743-P749 HydrophobicContact CD1-CG 4.06Å; F747-P749 HydrophobicContact CD2-CB 4.45Å; F747-P749 HydrophobicContact CE2-CB 3.89Å; F747-P749 WeakPolarHBondContact O-CD 3.48Å; P749-I754 HydrophobicContact CB-CD1 4.03Å; P749-I754 HydrophobicContact CB-CG1 4.02Å; P749-I754 HydrophobicContact CG-CD1 4.14Å
750Q84.5Confident88.1Confident60 Ų6060.4 Ų60.428%0.2828%0.282SS..  trans-71.4137.7178.1-61.9-175.86.200110.5E402 L748 K752 M753 I754E402-Q750 PolarHBondContact OE1-NE2 3.25Å; L748-Q750 PolarHBondContact O-N 3.3Å; Q750-K752 PolarHBondContact O-N 2.93Å; Q750-M753 HydrophobicContact CB-CB 4.4Å; Q750-M753 WeakPolarHBondContact O-CB 3.26Å; Q750-M753 PolarHBondContact O-N 3.39Å; Q750-I754 WeakPolarHBondContact O-CG1 3.29Å; Q750-I754 PolarHBondContact O-N 3.22Å
751K85.7Confident88.2Confident150 Ų15058.1 Ų58.165%0.65227%0.268SS*.Hα-helixtrans-51.9-35.5179.3-69-175.3178.4-179.80113.4K755K751-K755 WeakPolarHBondContact O-CG 3.17Å; K751-K755 PolarHBondContact O-N 3.24Å; K751-K755 VanDerWaalsContact O-N 3.15Å
752K85.8Confident88.3Confident104 Ų10454.9 Ų54.945%0.45225%0.254SS..Hα-helixtrans-65.4-49.8177.3-174.3179.5177.6-178.50111.8M397 Q750 I754 K755 E756M397-K752 VanDerWaalsContact CE-CE 3.46Å; Q750-K752 PolarHBondContact O-N 2.93Å; K752-I754 VanDerWaalsContact C-N 3.29Å; K752-I754 PolarHBondContact O-N 3.28Å; K752-K755 PolarHBondContact O-N 3.25Å; K752-K755 VanDerWaalsContact O-N 3.16Å; K752-E756 WeakPolarHBondContact CE-OE1 3.48Å; K752-E756 WeakPolarHBondContact CG-OE1 3.41Å; K752-E756 WeakPolarHBondContact O-CG 3.41Å; K752-E756 PolarHBondContact O-N 3.02Å
753M86.4Confident88.5Confident12 Ų1258.4 Ų58.46%0.05927%0.269CS..Hα-helixtrans-57.1-43.9175.5-179.9-175.8-7300111.1M390 R712 I713 F747 Q750 K755 E756 Q757M390-M753 HydrophobicContact CE-CE 4.28Å; R712-M753 HydrophobicContact CB-CE 3.99Å; R712-M753 HydrophobicContact CB-SD 4.09Å; I713-M753 HydrophobicContact CG1-CE 4.34Å; F747-M753 HydrophobicContact CE2-SD 4.43Å; Q750-M753 HydrophobicContact CB-CB 4.4Å; Q750-M753 WeakPolarHBondContact O-CB 3.26Å; Q750-M753 PolarHBondContact O-N 3.39Å; M753-K755 VanDerWaalsContact C-N 3.34Å; M753-K755 PolarHBondContact O-N 3.15Å; M753-E756 PolarHBondContact O-N 3.46Å; M753-Q757 HydrophobicContact CG-CG 4.24Å; M753-Q757 WeakPolarHBondContact O-CB 3.42Å; M753-Q757 VanDerWaalsContact O-CG 3.26Å; M753-Q757 WeakPolarHBondContact O-CG 3.35Å; M753-Q757 PolarHBondContact O-N 3.34Å
754I89.1Confident88.7Confident2 Ų262.8 Ų62.81%0.0129%0.289CS..Hα-helixtrans-58.7-46.1178.1-60.1170.8000110.9Q736 L739 P749 Q750 K752 Q757 I758Q736-I754 HydrophobicContact CG-CD1 4.44Å; Q736-I754 HydrophobicContact CG-CG2 4.38Å; L739-I754 HydrophobicContact CD2-CB 4.41Å; L739-I754 HydrophobicContact CD2-CD1 3.87Å; L739-I754 HydrophobicContact CD2-CG1 3.72Å; L739-I754 HydrophobicContact CD2-CG2 3.9Å; P749-I754 HydrophobicContact CB-CD1 4.03Å; P749-I754 HydrophobicContact CB-CG1 4.02Å; P749-I754 HydrophobicContact CG-CD1 4.14Å; Q750-I754 WeakPolarHBondContact O-CG1 3.29Å; Q750-I754 PolarHBondContact O-N 3.22Å; K752-I754 VanDerWaalsContact C-N 3.29Å; K752-I754 PolarHBondContact O-N 3.28Å; I754-Q757 PolarHBondContact O-N 3.16Å; I754-I758 HydrophobicContact CG2-CD1 3.78Å; I754-I758 HydrophobicContact CG2-CG1 4.42Å; I754-I758 VanDerWaalsContact O-CG1 3.25Å; I754-I758 WeakPolarHBondContact O-CG1 3Å; I754-I758 PolarHBondContact O-N 3.34Å
755K89.6Confident89Confident129 Ų12965.4 Ų65.456%0.56130%0.301SS*.Hα-helixtrans-60.8-49.1178.1-73.4-179.9177.4-170.70112K751 K752 M753 Q757 I758 E759K751-K755 WeakPolarHBondContact O-CG 3.17Å; K751-K755 PolarHBondContact O-N 3.24Å; K751-K755 VanDerWaalsContact O-N 3.15Å; K752-K755 PolarHBondContact O-N 3.25Å; K752-K755 VanDerWaalsContact O-N 3.16Å; M753-K755 VanDerWaalsContact C-N 3.34Å; M753-K755 PolarHBondContact O-N 3.15Å; K755-Q757 VanDerWaalsContact C-N 3.31Å; K755-Q757 PolarHBondContact O-N 3.39Å; K755-I758 PolarHBondContact O-N 2.94Å; K755-E759 WeakPolarHBondContact O-CG 3.44Å; K755-E759 PolarHBondContact O-N 3.12Å
756E89.9Confident89.4Confident54 Ų5466.1 Ų66.125%0.25230%0.298SS..Hα-helixtrans-60-41.3178.9-69.9169.3-176.500111.5K752 M753 E759 W760K752-E756 WeakPolarHBondContact CE-OE1 3.48Å; K752-E756 WeakPolarHBondContact CG-OE1 3.41Å; K752-E756 WeakPolarHBondContact O-CG 3.41Å; K752-E756 PolarHBondContact O-N 3.02Å; M753-E756 PolarHBondContact O-N 3.46Å; E756-E759 PolarHBondContact O-N 3.23Å; E756-W760 WeakPolarHBondContact O-CB 3.41Å; E756-W760 PolarHBondContact O-N 3.44Å
757Q92.5Very high89.7Confident14 Ų1464.7 Ų64.77%0.06529%0.291CS..Hα-helixtrans-71.7-33.1178.4-62.7-31.7-61.700112.8T716 Q717 I720 M753 I754 K755 L761T716-Q757 HydrophobicContact CG2-CB 4.1Å; T716-Q757 HydrophobicContact CG2-CG 3.95Å; Q717-Q757 HydrophobicContact CG-CB 4.24Å; Q717-Q757 HydrophobicContact CG-CG 4.19Å; I720-Q757 HydrophobicContact CD1-CB 4.2Å; M753-Q757 HydrophobicContact CG-CG 4.24Å; M753-Q757 WeakPolarHBondContact O-CB 3.42Å; M753-Q757 VanDerWaalsContact O-CG 3.26Å; M753-Q757 WeakPolarHBondContact O-CG 3.35Å; M753-Q757 PolarHBondContact O-N 3.34Å; I754-Q757 PolarHBondContact O-N 3.16Å; K755-Q757 VanDerWaalsContact C-N 3.31Å; K755-Q757 PolarHBondContact O-N 3.39Å; Q757-L761 WeakPolarHBondContact O-CB 3.48Å; Q757-L761 WeakPolarHBondContact O-CG 3.38Å; Q757-L761 PolarHBondContact O-N 2.93Å
758I91.5Very high90Very high6 Ų668.3 Ų68.33%0.03131%0.307CS..Hα-helixtrans-63.8-45.3172.1-72.3168.1000110.3I720 L735 I754 K755 L761 I762 I767 F777I720-I758 HydrophobicContact CD1-CG1 4.09Å; L735-I758 HydrophobicContact CD2-CD1 3.92Å; L735-I758 HydrophobicContact CD2-CG1 4.34Å; I754-I758 HydrophobicContact CG2-CD1 3.78Å; I754-I758 HydrophobicContact CG2-CG1 4.42Å; I754-I758 VanDerWaalsContact O-CG1 3.25Å; I754-I758 WeakPolarHBondContact O-CG1 3Å; I754-I758 PolarHBondContact O-N 3.34Å; K755-I758 PolarHBondContact O-N 2.94Å; I758-L761 PolarHBondContact O-N 3.5Å; I758-I762 HydrophobicContact CG2-CD1 3.87Å; I758-I762 HydrophobicContact CG2-CG1 4.49Å; I758-I762 VanDerWaalsContact O-CG1 3.29Å; I758-I762 WeakPolarHBondContact O-CG1 3.45Å; I758-I762 PolarHBondContact O-N 3.41Å; I758-I767 HydrophobicContact CG2-CD1 4.06Å; I758-F777 HydrophobicContact CD1-CE2 4.04Å; I758-F777 HydrophobicContact CD1-CZ 4.1Å; I758-F777 HydrophobicContact CG2-CD1 4.37Å; I758-F777 HydrophobicContact CG2-CE1 3.68Å; I758-F777 HydrophobicContact CG2-CE2 4.44Å; I758-F777 HydrophobicContact CG2-CZ 3.71Å
759E91.8Very high90.3Very high97 Ų9769.7 Ų69.745%0.45331%0.306SS..Hα-helixtrans-60.1-47.2177.1-73.2172179.600111.1K755 E756 L761 I762 E763K755-E759 WeakPolarHBondContact O-CG 3.44Å; K755-E759 PolarHBondContact O-N 3.12Å; E756-E759 PolarHBondContact O-N 3.23Å; E759-L761 VanDerWaalsContact C-N 3.31Å; E759-L761 PolarHBondContact O-N 3.07Å; E759-I762 WeakPolarHBondContact O-CB 3.49Å; E759-I762 PolarHBondContact O-N 3.38Å; E759-I762 VanDerWaalsContact O-N 3.1Å; E759-E763 WeakPolarHBondContact O-CG 3.41Å; E759-E763 PolarHBondContact O-N 3.45Å
760W93.2Very high90.6Very high86 Ų8670.3 Ų70.333%0.32631%0.309SS..Hα-helixtrans-56.7-44174.8-172.188.8000112.2Q717 E756 I762 E763 H764 Y766Q717-W760 HydrophobicContact CG-CE3 4.29Å; Q717-W760 HydrophobicContact CG-CZ3 4.49Å; E756-W760 WeakPolarHBondContact O-CB 3.41Å; E756-W760 PolarHBondContact O-N 3.44Å; W760-I762 VanDerWaalsContact C-N 3.33Å; W760-I762 PolarHBondContact O-N 3.46Å; W760-E763 PolarHBondContact O-N 2.94Å; W760-H764 AromaticContact CD1-CE1 3.6Å; W760-H764 AromaticContact CD1-ND1 3.9Å; W760-H764 AromaticContact CD2-CE1 3.89Å; W760-H764 AromaticContact CD2-ND1 3.63Å; W760-H764 AromaticContact CE2-CE1 3.3Å; W760-H764 AromaticContact CE2-ND1 3.48Å; W760-H764 AromaticContact CE2-NE2 3.69Å; W760-H764 AromaticContact CG-ND1 3.91Å; W760-H764 AromaticContact CZ2-CD2 3.76Å; W760-H764 AromaticContact CZ2-CE1 3.71Å; W760-H764 AromaticContact CZ2-CG 3.94Å; W760-H764 AromaticContact CZ2-ND1 3.89Å; W760-H764 AromaticContact CZ2-NE2 3.6Å; W760-H764 AromaticContact NE1-CE1 3.12Å; W760-H764 PolarHBondContact NE1-CE1 2.86Å; W760-H764 AromaticContact NE1-ND1 3.67Å; W760-H764 AromaticContact NE1-NE2 3.72Å; W760-H764 PolarHBondContact O-N 3.5Å; W760-H764 PolarHBondContact O-ND1 3.42Å; W760-Y766 HydrophobicContact CH2-CE2 4.4Å; W760-Y766 HydrophobicContact CZ3-CD2 4.42Å; W760-Y766 HydrophobicContact CZ3-CE2 4.14Å
761L93.1Very high90.7Very high0 Ų076.3 Ų76.30%034%0.337CS..Hα-helixtrans-68-29.6178.2-71.6171000113.3I720 I721 Q757 I758 E759 K765 Y766 I767I720-L761 HydrophobicContact CB-CD1 3.72Å; I720-L761 HydrophobicContact CD1-CD1 4.1Å; I720-L761 HydrophobicContact CG2-CD1 3.4Å; I720-L761 VanDerWaalsContact CG2-CD1 3.4Å; I721-L761 HydrophobicContact CD1-CD2 3.69Å; I721-L761 HydrophobicContact CG1-CD1 4.38Å; I721-L761 HydrophobicContact CG1-CD2 3.75Å; Q757-L761 WeakPolarHBondContact O-CB 3.48Å; Q757-L761 WeakPolarHBondContact O-CG 3.38Å; Q757-L761 PolarHBondContact O-N 2.93Å; I758-L761 PolarHBondContact O-N 3.5Å; E759-L761 VanDerWaalsContact C-N 3.31Å; E759-L761 PolarHBondContact O-N 3.07Å; L761-K765 PolarHBondContact O-N 3.23Å; L761-Y766 HydrophobicContact CD2-CD2 3.68Å; L761-Y766 HydrophobicContact CD2-CE2 4.45Å; L761-Y766 HydrophobicContact CD2-CG 4.02Å; L761-Y766 PolarHBondContact O-N 2.86Å; L761-I767 HydrophobicContact CB-CD1 3.81Å; L761-I767 HydrophobicContact CB-CG1 3.85Å; L761-I767 HydrophobicContact CD1-CD1 4.47Å; L761-I767 PolarHBondContact O-N 3.49Å
762I92Very high90.7Very high48 Ų4873.7 Ų73.725%0.24634%0.338CS..Hα-helixtrans-70-48.3173.3-67.4164.7000110.1I758 E759 W760 H764 K765 I767 R769 F777I758-I762 HydrophobicContact CG2-CD1 3.87Å; I758-I762 HydrophobicContact CG2-CG1 4.49Å; I758-I762 VanDerWaalsContact O-CG1 3.29Å; I758-I762 WeakPolarHBondContact O-CG1 3.45Å; I758-I762 PolarHBondContact O-N 3.41Å; E759-I762 WeakPolarHBondContact O-CB 3.49Å; E759-I762 PolarHBondContact O-N 3.38Å; E759-I762 VanDerWaalsContact O-N 3.1Å; W760-I762 VanDerWaalsContact C-N 3.33Å; W760-I762 PolarHBondContact O-N 3.46Å; I762-H764 PolarHBondContact O-N 3.28Å; I762-K765 PolarHBondContact O-N 2.82Å; I762-I767 WeakPolarHBondContact CA-O 3.3Å; I762-I767 HydrophobicContact CG1-CD1 4.03Å; I762-I767 HydrophobicContact CG1-CG1 3.66Å; I762-R769 HydrophobicContact CD1-CG 3.97Å; I762-F777 HydrophobicContact CD1-CE1 4.47Å
763E92.9Very high90.8Very high143 Ų14371.5 Ų71.567%0.66833%0.331SS*.Hα-helixtrans-57.9-39178.2-71.6176176.600111.9E759 W760 K765E759-E763 WeakPolarHBondContact O-CG 3.41Å; E759-E763 PolarHBondContact O-N 3.45Å; W760-E763 PolarHBondContact O-N 2.94Å; E763-K765 PolarHBondContact O-N 3.45Å
764H92.8Very high90.8Very high94 Ų9476.3 Ų76.344%0.43536%0.356SS..THydrogen-bonded Turntrans-85.69.4178.6-66.172.6000113.6W760 I762 Y766W760-H764 AromaticContact CD1-CE1 3.6Å; W760-H764 AromaticContact CD1-ND1 3.9Å; W760-H764 AromaticContact CD2-CE1 3.89Å; W760-H764 AromaticContact CD2-ND1 3.63Å; W760-H764 AromaticContact CE2-CE1 3.3Å; W760-H764 AromaticContact CE2-ND1 3.48Å; W760-H764 AromaticContact CE2-NE2 3.69Å; W760-H764 AromaticContact CG-ND1 3.91Å; W760-H764 AromaticContact CZ2-CD2 3.76Å; W760-H764 AromaticContact CZ2-CE1 3.71Å; W760-H764 AromaticContact CZ2-CG 3.94Å; W760-H764 AromaticContact CZ2-ND1 3.89Å; W760-H764 AromaticContact CZ2-NE2 3.6Å; W760-H764 AromaticContact NE1-CE1 3.12Å; W760-H764 PolarHBondContact NE1-CE1 2.86Å; W760-H764 AromaticContact NE1-ND1 3.67Å; W760-H764 AromaticContact NE1-NE2 3.72Å; W760-H764 PolarHBondContact O-N 3.5Å; W760-H764 PolarHBondContact O-ND1 3.42Å; I762-H764 PolarHBondContact O-N 3.28Å; H764-Y766 VanDerWaalsContact C-N 3.28Å; H764-Y766 HydrophobicContact CB-CD2 3.72Å; H764-Y766 HydrophobicContact CB-CE2 3.74Å; H764-Y766 PolarHBondContact O-N 2.96Å
765K91.3Very high90.8Very high165 Ų16581 Ų8172%0.71738%0.38SS*.THydrogen-bonded Turntrans60.927.1174.5-53178.6179.5177.80114.9L761 I762 E763 M780L761-K765 PolarHBondContact O-N 3.23Å; I762-K765 PolarHBondContact O-N 2.82Å; E763-K765 PolarHBondContact O-N 3.45Å; K765-M780 VanDerWaalsContact O-CB 3.25Å; K765-M780 WeakPolarHBondContact O-CB 3.32Å
766Y90.5Very high90.8Very high99 Ų9975.6 Ų75.639%0.38836%0.359SS..SBendtrans-79.1-33.2171-71.5-74.5000112.1I721 W760 L761 H764 Y779 M780I721-Y766 HydrophobicContact CD1-CD1 4.26Å; I721-Y766 HydrophobicContact CD1-CE1 4.46Å; I721-Y766 HydrophobicContact CD1-CG 4.38Å; W760-Y766 HydrophobicContact CH2-CE2 4.4Å; W760-Y766 HydrophobicContact CZ3-CD2 4.42Å; W760-Y766 HydrophobicContact CZ3-CE2 4.14Å; L761-Y766 HydrophobicContact CD2-CD2 3.68Å; L761-Y766 HydrophobicContact CD2-CE2 4.45Å; L761-Y766 HydrophobicContact CD2-CG 4.02Å; L761-Y766 PolarHBondContact O-N 2.86Å; H764-Y766 VanDerWaalsContact C-N 3.28Å; H764-Y766 HydrophobicContact CB-CD2 3.72Å; H764-Y766 HydrophobicContact CB-CE2 3.74Å; H764-Y766 PolarHBondContact O-N 2.96Å; Y766-Y779 WeakPolarHBondContact O-CD2 3.38Å; Y766-M780 PolarHBondContact O-N 3.41Å
767I92.9Very high91Very high2 Ų273.2 Ų73.21%0.0135%0.347CS..EExtended strand (participates in β ladder)trans-139.1157.2-18062.7177.9000109.9M724 I758 L761 I762 I778 Y779M724-I767 HydrophobicContact CB-CG2 4.07Å; M724-I767 HydrophobicContact CE-CB 4.11Å; M724-I767 HydrophobicContact CE-CG2 3.62Å; M724-I767 HydrophobicContact CG-CG2 3.77Å; M724-I767 HydrophobicContact SD-CG2 4.36Å; I758-I767 HydrophobicContact CG2-CD1 4.06Å; L761-I767 HydrophobicContact CB-CD1 3.81Å; L761-I767 HydrophobicContact CB-CG1 3.85Å; L761-I767 HydrophobicContact CD1-CD1 4.47Å; L761-I767 PolarHBondContact O-N 3.49Å; I762-I767 WeakPolarHBondContact CA-O 3.3Å; I762-I767 HydrophobicContact CG1-CD1 4.03Å; I762-I767 HydrophobicContact CG1-CG1 3.66Å; I767-I778 CarbonylContact C-O 3.6Å; I767-I778 VanDerWaalsContact CA-O 3.29Å; I767-I778 WeakPolarHBondContact CA-O 3.25Å; I767-Y779 HydrophobicContact CG2-CD2 4.41Å
768K92.6Very high91Very high80 Ų8074.5 Ų74.535%0.34835%0.354SS..EExtended strand (participates in β ladder)trans-128.515817067.2168.3166.9176.60110.5F777 I778 M780K768-F777 CarbonylContact O-C 3.52Å; K768-F777 WeakPolarHBondContact O-CA 3.38Å; K768-I778 HydrophobicContact CG-CB 3.83Å; K768-I778 HydrophobicContact CG-CG2 4.45Å; K768-I778 PolarHBondContact N-O 3.11Å; K768-I778 PolarHBondContact O-N 3.33Å; K768-M780 HydrophobicContact CB-CG 3.75Å; K768-M780 HydrophobicContact CB-SD 3.78Å; K768-M780 HydrophobicContact CD-CE 4.44Å; K768-M780 HydrophobicContact CD-CG 4.35Å; K768-M780 HydrophobicContact CD-SD 3.34Å; K768-M780 WeakPolarHBondContact CD-SD 3.45Å; K768-M780 HydrophobicContact CG-CG 3.77Å; K768-M780 HydrophobicContact CG-SD 3.45Å; K768-M780 WeakPolarHBondContact CG-SD 3.42Å
769R92.9Very high91.1Very high110 Ų11075.7 Ų75.742%0.41536%0.359SS..EExtended strand (participates in β ladder)trans-77.4146.7166.2-64.5-177.4-175.4178.82.4109.2I762 F777I762-R769 HydrophobicContact CD1-CG 3.97Å; R769-F777 HydrophobicContact CG-CD1 4.12Å; R769-F777 HydrophobicContact CG-CE1 4.03Å
770D90.9Very high90.8Very high22 Ų2275.4 Ų75.412%0.11836%0.358CS..  trans-65.7144.2171.3-159.4-48.5000109.8R729 S772 D773 T776 I778R729-D770 IonicContact CZ-OD2 3.73Å; R729-D770 IonicContact NE-OD2 2.83Å; R729-D770 PolarHBondContact NE-OD2 3.41Å; R729-D770 IonicContact NH2-OD2 3.21Å; R729-D770 PolarHBondContact NH2-OD2 3.02Å; D770-S772 PolarHBondContact O-N 3.42Å; D770-S772 PolarHBondContact OD1-N 2.99Å; D770-S772 PolarHBondContact OD1-OG 3.05Å; D770-D773 WeakPolarHBondContact CB-O 3.06Å; D770-T776 HydrophobicContact CB-CG2 4.07Å; D770-T776 PolarHBondContact N-O 2.95Å; D770-I778 HydrophobicContact CB-CD1 4.04Å; D770-I778 HydrophobicContact CB-CG1 4.44Å
771E87.4Confident89.7Confident186 Ų18676.6 Ų76.687%0.86939%0.386SS*.SBendtrans-70.7-26.1178-67.4173.2-161.800111.3
772S86Confident89.5Confident95 Ų9580.4 Ų80.466%0.66441%0.405SS*.SBendtrans-90.3-28.1-179.960.20000114.1D770D770-S772 PolarHBondContact O-N 3.42Å; D770-S772 PolarHBondContact OD1-N 2.99Å; D770-S772 PolarHBondContact OD1-OG 3.05Å
773D88.6Confident89.4Confident58 Ų5882.1 Ų82.131%0.3141%0.414SS..  trans-147.4114.4-177.6175.225.3000112D770 N775 T776D770-D773 WeakPolarHBondContact CB-O 3.06Å; D773-N775 PolarHBondContact O-N 3.31Å; D773-N775 VanDerWaalsContact O-N 3.16Å; D773-N775 WeakPolarHBondContact OD1-CB 3.44Å; D773-N775 PolarHBondContact OD1-N 3.5Å; D773-T776 PolarHBondContact O-N 3.35Å; D773-T776 PolarHBondContact OD2-N 3.23Å; D773-T776 PolarHBondContact OD2-OG1 3.22Å
774I85.6Confident89.2Confident113 Ų11378.7 Ų78.758%0.57940%0.4SS*.THydrogen-bonded Turntrans-61.5-24.6178.7-64.4173.8000112T776I774-T776 VanDerWaalsContact C-N 3.27Å
775N88.9Confident89Confident99 Ų9977.8 Ų77.853%0.52940%0.398SS..THydrogen-bonded Turntrans-83.6-1177.6-65.3-49.4000113.4S731 N732 D773S731-N775 CarbonylContact C-O 3.56Å; S731-N775 WeakPolarHBondContact CA-O 3.17Å; N732-N775 WeakPolarHBondContact CB-O 3.48Å; N732-N775 PolarHBondContact N-O 3.35Å; D773-N775 PolarHBondContact O-N 3.31Å; D773-N775 VanDerWaalsContact O-N 3.16Å; D773-N775 WeakPolarHBondContact OD1-CB 3.44Å; D773-N775 PolarHBondContact OD1-N 3.5Å
776T90.6Very high88.8Confident17 Ų1772.4 Ų72.410%0.10438%0.378CS..EExtended strand (participates in β ladder)trans-109.2132.4177.6-650000110.2R729 D770 D773 I774R729-T776 HydrophobicContact CG-CG2 3.62Å; D770-T776 HydrophobicContact CB-CG2 4.07Å; D770-T776 PolarHBondContact N-O 2.95Å; D773-T776 PolarHBondContact O-N 3.35Å; D773-T776 PolarHBondContact OD2-N 3.23Å; D773-T776 PolarHBondContact OD2-OG1 3.22Å; I774-T776 VanDerWaalsContact C-N 3.27Å
777F93.3Very high88.7Confident4 Ų470.6 Ų70.62%0.01838%0.377CS..EExtended strand (participates in β ladder)trans-109.3142.3179.2-55.5-63.9000110.4M724 R729 I730 N732 L735 I758 I762 K768 R769M724-F777 HydrophobicContact CE-CB 3.65Å; M724-F777 HydrophobicContact SD-CB 4.02Å; R729-F777 VanDerWaalsContact CA-O 3.27Å; R729-F777 WeakPolarHBondContact CA-O 3.31Å; I730-F777 PolarHBondContact N-O 3.44Å; I730-F777 PolarHBondContact O-N 3.01Å; N732-F777 HydrophobicContact CB-CE2 3.81Å; N732-F777 HydrophobicContact CB-CZ 4.38Å; N732-F777 WeakPolarHBondContact ND2-CE2 3.37Å; N732-F777 WeakPolarHBondContact ND2-CZ 3.29Å; L735-F777 HydrophobicContact CD2-CD2 3.8Å; L735-F777 HydrophobicContact CD2-CE2 4Å; I758-F777 HydrophobicContact CD1-CE2 4.04Å; I758-F777 HydrophobicContact CD1-CZ 4.1Å; I758-F777 HydrophobicContact CG2-CD1 4.37Å; I758-F777 HydrophobicContact CG2-CE1 3.68Å; I758-F777 HydrophobicContact CG2-CE2 4.44Å; I758-F777 HydrophobicContact CG2-CZ 3.71Å; I762-F777 HydrophobicContact CD1-CE1 4.47Å; K768-F777 CarbonylContact O-C 3.52Å; K768-F777 WeakPolarHBondContact O-CA 3.38Å; R769-F777 HydrophobicContact CG-CD1 4.12Å; R769-F777 HydrophobicContact CG-CE1 4.03Å
778I91.9Very high88.4Confident40 Ų4075.5 Ų75.521%0.20540%0.403CS..EExtended strand (participates in β ladder)trans-121.7135.1177.7-55.8169.4000108.8K728 R729 I767 K768 D770K728-I778 CarbonylContact O-C 3.58Å; K728-I778 WeakPolarHBondContact O-CA 3.18Å; R729-I778 HydrophobicContact CG-CG1 4.2Å; I767-I778 CarbonylContact C-O 3.6Å; I767-I778 VanDerWaalsContact CA-O 3.29Å; I767-I778 WeakPolarHBondContact CA-O 3.25Å; K768-I778 HydrophobicContact CG-CB 3.83Å; K768-I778 HydrophobicContact CG-CG2 4.45Å; K768-I778 PolarHBondContact N-O 3.11Å; K768-I778 PolarHBondContact O-N 3.33Å; D770-I778 HydrophobicContact CB-CD1 4.04Å; D770-I778 HydrophobicContact CB-CG1 4.44Å
779Y94Very high88.1Confident32 Ų3275.2 Ų75.213%0.12541%0.407CS..EExtended strand (participates in β ladder)trans-75137176.8-175.4-109.3000111.5M724 K725 K728 Y766 I767 A781M724-Y779 HydrophobicContact CB-CD2 3.77Å; M724-Y779 HydrophobicContact CB-CG 4.38Å; M724-Y779 WeakPolarHBondContact O-CB 3.32Å; K725-Y779 WeakPolarHBondContact CE-OH 3.49Å; K725-Y779 HydrophobicContact CG-CD2 4.35Å; K725-Y779 HydrophobicContact CG-CE1 3.85Å; K725-Y779 HydrophobicContact CG-CE2 3.63Å; K725-Y779 WeakPolarHBondContact CG-OH 3.42Å; K728-Y779 HydrophobicContact CD-CD1 3.97Å; K728-Y779 HydrophobicContact CD-CG 4.47Å; K728-Y779 PolarHBondContact O-N 3.42Å; Y766-Y779 WeakPolarHBondContact O-CD2 3.38Å; I767-Y779 HydrophobicContact CG2-CD2 4.41Å; Y779-A781 HydrophobicContact CD1-CB 4.48Å; Y779-A781 VanDerWaalsContact CD1-O 3.22Å; Y779-A781 WeakPolarHBondContact CD1-O 3.26Å; Y779-A781 HydrophobicContact CE1-CB 3.59Å; Y779-A781 WeakPolarHBondContact CE1-O 3.43Å; Y779-A781 HydrophobicContact CE2-CB 4.47Å; Y779-A781 VanDerWaalsContact OH-CB 3.32Å; Y779-A781 WeakPolarHBondContact OH-CB 3.39Å
780M86Confident87.7Confident91 Ų9172.3 Ų72.345%0.44841%0.407SS..  trans-105.45.4-168.3-77.2-72.2-72.900115.4K765 Y766 K768K765-M780 VanDerWaalsContact O-CB 3.25Å; K765-M780 WeakPolarHBondContact O-CB 3.32Å; Y766-M780 PolarHBondContact O-N 3.41Å; K768-M780 HydrophobicContact CB-CG 3.75Å; K768-M780 HydrophobicContact CB-SD 3.78Å; K768-M780 HydrophobicContact CD-CE 4.44Å; K768-M780 HydrophobicContact CD-CG 4.35Å; K768-M780 HydrophobicContact CD-SD 3.34Å; K768-M780 WeakPolarHBondContact CD-SD 3.45Å; K768-M780 HydrophobicContact CG-CG 3.77Å; K768-M780 HydrophobicContact CG-SD 3.45Å; K768-M780 WeakPolarHBondContact CG-SD 3.42Å
781A69.3Low87.4Confident110 Ų11076.8 Ų76.891%0.90943%0.433SS*.  trans-118.20-179.100000115.1Y779Y779-A781 HydrophobicContact CD1-CB 4.48Å; Y779-A781 VanDerWaalsContact CD1-O 3.22Å; Y779-A781 WeakPolarHBondContact CD1-O 3.26Å; Y779-A781 HydrophobicContact CE1-CB 3.59Å; Y779-A781 WeakPolarHBondContact CE1-O 3.43Å; Y779-A781 HydrophobicContact CE2-CB 4.47Å; Y779-A781 VanDerWaalsContact OH-CB 3.32Å; Y779-A781 WeakPolarHBondContact OH-CB 3.39Å

Retrieved 781 of 781 residues in 1152.9 ms (Link to these results)