A0A087Y477_POEFO Loading...

Terpene cyclase/mutase family member

Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.

AlphaFold DB , UniProt , Accession A0A087Y477, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 735 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M33.2Very low67.6Low245 Ų24598.3 Ų98.3100%1.20753%0.529SS*.  0101.30-78.6-168.4-8300108.2
2S35.4Very low69.9Low99 Ų9990.7 Ų90.769%0.69249%0.491SS*.  trans-171.451.2156.263.50000110.2G4S2-G4 PolarHBondContact O-N 2.82Å
3E31.9Very low72.1Confident207 Ų20784.8 Ų84.897%0.96746%0.46SS*.SBendtrans-75.9107.2147.9-77.5-179.2155.600105.1
4G43.1Very low74Confident77 Ų7787.1 Ų87.179%0.79446%0.46SS*.  trans135.5-5.7169.400000118.6S2 Q6S2-G4 PolarHBondContact O-N 2.82Å; G4-Q6 PolarHBondContact O-N 3.37Å
5T55.3Low75.6Confident67 Ų6790.3 Ų90.341%0.41147%0.468SS..  trans-79.1111.7177.4-39.10000110.2L7 P138T5-L7 PolarHBondContact O-N 2.88Å; T5-L7 VanDerWaalsContact O-N 3.1Å; T5-P138 HydrophobicContact CG2-CB 4.33Å
6Q69.6Low77Confident135 Ų13587.3 Ų87.363%0.63146%0.455SS*.  trans-62.6109.5173.1-174.5177.8300109.7G4 R8G4-Q6 PolarHBondContact O-N 3.37Å; Q6-R8 WeakPolarHBondContact CG-O 3.36Å; Q6-R8 PolarHBondContact NE2-O 3.19Å
7L89.6Confident78.3Confident88 Ų8892.4 Ų92.446%0.46148%0.477SS..  trans-82.9-15-171.5-64.7178.7000114.9T5 K149T5-L7 PolarHBondContact O-N 2.88Å; T5-L7 VanDerWaalsContact O-N 3.1Å; L7-K149 HydrophobicContact CB-CG 4.32Å
8R95.1Very high79.4Confident37 Ų3790.5 Ų90.514%0.1447%0.471CS..  trans-134.1147.6179.2-69.5-173.4-175.8-71.53109.9Q6 E147 D148 K149 E635Q6-R8 WeakPolarHBondContact CG-O 3.36Å; Q6-R8 PolarHBondContact NE2-O 3.19Å; R8-E147 WeakPolarHBondContact CD-O 3.25Å; R8-E147 PolarHBondContact NH1-O 2.96Å; R8-D148 IonicContact CZ-OD1 3.47Å; R8-D148 VanDerWaalsContact NH1-C 3.29Å; R8-D148 IonicContact NH1-OD1 3.95Å; R8-D148 PolarHBondContact NH1-OD1 3.26Å; R8-K149 HydrophobicContact CG-CG 3.56Å; R8-E635 IonicContact CZ-OE1 3.42Å; R8-E635 IonicContact NE-OE1 3.78Å; R8-E635 PolarHBondContact NE-OE1 3.36Å; R8-E635 IonicContact NH2-OE1 3.39Å; R8-E635 PolarHBondContact NH2-OE1 3.29Å
9R95.7Very high80.4Confident73 Ų7388.2 Ų88.228%0.27547%0.467SS..  trans-115.298170.1-175.3-177-65.4135.77.6109.3Y14 S134 Q136 L137 I146R9-Y14 HydrophobicContact CG-CD2 4.34Å; R9-Y14 HydrophobicContact CG-CE2 3.93Å; R9-S134 PolarHBondContact NH1-O 3.46Å; R9-Q136 VanDerWaalsContact CZ-O 3.32Å; R9-Q136 PolarHBondContact NH1-O 3.42Å; R9-Q136 PolarHBondContact NH2-O 3.29Å; R9-L137 HydrophobicContact CB-CD2 4.16Å; R9-I146 VanDerWaalsContact O-O 3.08Å
10R97.5Very high81.3Confident47 Ų4784.7 Ų84.718%0.17745%0.449CS..  trans-84.8165.7172.6-56.5-165.7-171.3-78.85.6111.3Y14 E147 D633 E635 N692R10-Y14 VanDerWaalsContact O-CE2 3.32Å; R10-Y14 WeakPolarHBondContact O-CE2 3.33Å; R10-Y14 PolarHBondContact O-OH 3.49Å; R10-E147 IonicContact NH1-OE2 3.83Å; R10-E147 PolarHBondContact NH1-OE2 3.06Å; R10-D633 IonicContact CZ-OD1 3.23Å; R10-D633 IonicContact CZ-OD2 3.79Å; R10-D633 IonicContact NE-OD1 3.95Å; R10-D633 IonicContact NE-OD2 3.93Å; R10-D633 IonicContact NH2-OD2 3.75Å; R10-D633 PolarHBondContact NH2-OD2 3.07Å; R10-E635 IonicContact CZ-OE1 3.32Å; R10-E635 IonicContact CZ-OE2 2.68Å; R10-E635 VanDerWaalsContact CZ-OE2 3.24Å; R10-E635 IonicContact NH1-OE1 2.64Å; R10-E635 IonicContact NH1-OE2 2.89Å; R10-E635 PolarHBondContact NH1-OE2 2.85Å; R10-E635 IonicContact NH2-OE1 3.59Å; R10-E635 PolarHBondContact NH2-OE1 2.89Å; R10-E635 IonicContact NH2-OE2 3.31Å; R10-E635 PolarHBondContact NH2-OE2 3.16Å; R10-N692 WeakPolarHBondContact CB-OD1 3.46Å
11G97.1Very high82Confident6 Ų684.3 Ų84.36%0.06245%0.447CS..SBendtrans855.7167.400000116.1Y14 E147 E691G11-Y14 WeakPolarHBondContact CA-OH 3.49Å; G11-E147 PolarHBondContact N-OE1 3.44Å; G11-E691 WeakPolarHBondContact CA-O 3.43Å
12G95.7Very high85.1Confident7 Ų773.1 Ų73.17%0.07239%0.392CS..PPolyproline II helixtrans-70.9171.8174.700000113.1
13P98.3Very high88Confident14 Ų1471 Ų719%0.09138%0.377CS..PPolyproline II helixcis-72.81430.230-34.8000112.7L374 D375P13-L374 HydrophobicContact CB-CB 4.4Å; P13-L374 HydrophobicContact CG-CD1 4.38Å; P13-D375 VanDerWaalsContact CB-OD2 3.32Å; P13-D375 WeakPolarHBondContact CB-OD2 3.33Å
14Y98.4Very high91.1Very high117 Ų11762.9 Ų62.946%0.45934%0.337SS..PPolyproline II helixtrans-103.5147.7176.8-69.8-70.3000110.8R9 R10 G11 T16 L374 D375R9-Y14 HydrophobicContact CG-CD2 4.34Å; R9-Y14 HydrophobicContact CG-CE2 3.93Å; R10-Y14 VanDerWaalsContact O-CE2 3.32Å; R10-Y14 WeakPolarHBondContact O-CE2 3.33Å; R10-Y14 PolarHBondContact O-OH 3.49Å; G11-Y14 WeakPolarHBondContact CA-OH 3.49Å; Y14-T16 PolarHBondContact O-N 3.4Å; Y14-L374 CarbonylContact O-C 3.58Å; Y14-D375 WeakPolarHBondContact O-CB 3.31Å
15K98.5Very high93.7Very high135 Ų13559.2 Ų59.259%0.58730%0.3SS*.PPolyproline II helixtrans-67.4123.3172.1-170.5177.5176.2175.90109.7G58 L374K15-G58 WeakPolarHBondContact CE-O 3.45Å; K15-G58 PolarHBondContact NZ-O 2.89Å; K15-L374 WeakPolarHBondContact CA-O 3.36Å
16T98.5Very high95.8Very high42 Ų4257 Ų5726%0.25828%0.284SS..  trans-118.6172.5173.261.80000111.2Y14 R130 S134 L374Y14-T16 PolarHBondContact O-N 3.4Å; T16-R130 PolarHBondContact O-NH2 2.92Å; T16-R130 PolarHBondContact OG1-NE 3.48Å; T16-R130 VanDerWaalsContact OG1-NE 3.16Å; T16-R130 PolarHBondContact OG1-NH2 3.43Å; T16-S134 WeakPolarHBondContact CB-OG 3.35Å; T16-S134 WeakPolarHBondContact CG2-OG 3.44Å; T16-S134 PolarHBondContact OG1-OG 3.34Å; T16-L374 PolarHBondContact N-O 3.47Å
17E98.4Very high97.2Very high175 Ų17550.7 Ų50.782%0.81825%0.254SS*.  trans-65.8128176.1-171.9174.8-178.500110.9R130E17-R130 WeakPolarHBondContact O-CD 3.49Å; E17-R130 PolarHBondContact O-NE 3.16Å
18P98.3Very high97.6Very high58 Ų5854.5 Ų54.538%0.37726%0.263SS..  trans-76.4150.2-178.132.8-36000113.6T20 L22 R130P18-T20 WeakPolarHBondContact CB-O 3.46Å; P18-L22 HydrophobicContact CB-CD1 3.81Å; P18-L22 HydrophobicContact CB-CD2 3.75Å; P18-L22 HydrophobicContact CB-CG 3.57Å; P18-L22 HydrophobicContact CG-CD1 4.03Å; P18-L22 HydrophobicContact CG-CG 4Å; P18-R130 VanDerWaalsContact CA-CZ 3.41Å
19A98Very high97.7Very high47 Ų4753.2 Ų53.239%0.38826%0.259SS..SBendtrans-95.4-4.2177.200000112.6K126 E127 R130A19-K126 HydrophobicContact CB-CB 4Å; A19-E127 PolarHBondContact N-OE1 3.13Å; A19-R130 HydrophobicContact CB-CB 4.08Å
20T98.1Very high97.8Very high18 Ų1851.9 Ų51.911%0.1126%0.263CS..SBendtrans-141.1166.4179.858.90000110.1P18 L22 W25 A123 K126 E127P18-T20 WeakPolarHBondContact CB-O 3.46Å; T20-L22 PolarHBondContact O-N 3.32Å; T20-L22 VanDerWaalsContact O-N 3.1Å; T20-W25 PolarHBondContact OG1-NE1 3.21Å; T20-A123 HydrophobicContact CG2-CB 4.06Å; T20-K126 HydrophobicContact CG2-CB 4.07Å; T20-K126 HydrophobicContact CG2-CD 4.15Å; T20-E127 WeakPolarHBondContact CB-OE1 3.48Å; T20-E127 HydrophobicContact CG2-CG 4.09Å; T20-E127 PolarHBondContact N-OE1 2.91Å; T20-E127 PolarHBondContact OG1-OE1 3.3Å
21D97.4Very high97.9Very high77 Ų7754.1 Ų54.141%0.41228%0.275SS..  trans-72.7104172.3-177.8-6.5000110.3S23 R24D21-S23 PolarHBondContact O-N 3.12Å; D21-S23 VanDerWaalsContact O-N 3.11Å; D21-S23 VanDerWaalsContact OD1-CB 3.28Å; D21-S23 WeakPolarHBondContact OD1-CB 3.49Å; D21-S23 PolarHBondContact OD1-N 3.25Å; D21-S23 PolarHBondContact OD1-OG 3.27Å; D21-S23 PolarHBondContact OD2-OG 2.95Å; D21-S23 VanDerWaalsContact OD2-OG 3.14Å; D21-R24 HydrophobicContact CB-CG 3.93Å; D21-R24 WeakPolarHBondContact O-CB 3.34Å; D21-R24 PolarHBondContact O-N 3.15Å; D21-R24 WeakPolarHBondContact OD2-CG 3.46Å
22L98.2Very high97.9Very high9 Ų953.8 Ų53.85%0.04727%0.272CS..G310 helixtrans-58.1-24.8180-63-175.1000113.2P18 T20 R24 W25 Q49 L57 L59P18-L22 HydrophobicContact CB-CD1 3.81Å; P18-L22 HydrophobicContact CB-CD2 3.75Å; P18-L22 HydrophobicContact CB-CG 3.57Å; P18-L22 HydrophobicContact CG-CD1 4.03Å; P18-L22 HydrophobicContact CG-CG 4Å; T20-L22 PolarHBondContact O-N 3.32Å; T20-L22 VanDerWaalsContact O-N 3.1Å; L22-R24 PolarHBondContact O-N 2.83Å; L22-W25 PolarHBondContact O-N 3.04Å; L22-Q49 PolarHBondContact O-NE2 2.68Å; L22-L57 HydrophobicContact CB-CD1 4.48Å; L22-L57 HydrophobicContact CD1-CB 4.48Å; L22-L57 VanDerWaalsContact O-CD1 3.3Å; L22-L57 WeakPolarHBondContact O-CD1 3.29Å; L22-L59 HydrophobicContact CB-CD1 4.09Å; L22-L59 HydrophobicContact CB-CD2 3.97Å; L22-L59 HydrophobicContact CB-CG 4.24Å; L22-L59 HydrophobicContact CD1-CD2 4.24Å
23S95.7Very high98.1Very high54 Ų5457.3 Ų57.338%0.37828%0.284SS..G310 helixtrans-70.9-13.617977.50000113.4D21 R26D21-S23 PolarHBondContact O-N 3.12Å; D21-S23 VanDerWaalsContact O-N 3.11Å; D21-S23 VanDerWaalsContact OD1-CB 3.28Å; D21-S23 WeakPolarHBondContact OD1-CB 3.49Å; D21-S23 PolarHBondContact OD1-N 3.25Å; D21-S23 PolarHBondContact OD1-OG 3.27Å; D21-S23 PolarHBondContact OD2-OG 2.95Å; D21-S23 VanDerWaalsContact OD2-OG 3.14Å; S23-R26 PolarHBondContact O-NH1 2.7Å; S23-R26 PolarHBondContact O-NH2 3.43Å
24R97.2Very high98.1Very high37 Ų3757 Ų5714%0.1428%0.281CS..G310 helixtrans-98.2-6.6-177.9-55.5-17270.493.816.1114.1D21 L22 Y38 V39 D40 D41 E43D21-R24 HydrophobicContact CB-CG 3.93Å; D21-R24 WeakPolarHBondContact O-CB 3.34Å; D21-R24 PolarHBondContact O-N 3.15Å; D21-R24 WeakPolarHBondContact OD2-CG 3.46Å; L22-R24 PolarHBondContact O-N 2.83Å; R24-Y38 HydrophobicContact CB-CD2 4.18Å; R24-Y38 HydrophobicContact CB-CE2 3.72Å; R24-V39 HydrophobicContact CB-CB 4.5Å; R24-V39 PolarHBondContact NE-O 3.33Å; R24-V39 PolarHBondContact NH2-O 3.33Å; R24-V39 WeakPolarHBondContact O-CG2 3.46Å; R24-V39 PolarHBondContact O-N 2.76Å; R24-D40 PolarHBondContact NH2-O 3.44Å; R24-D41 WeakPolarHBondContact CD-OD1 3.4Å; R24-D41 VanDerWaalsContact CZ-CA 3.48Å; R24-D41 IonicContact NE-OD1 3.57Å; R24-D41 PolarHBondContact NH1-O 3.01Å; R24-E43 PolarHBondContact NH2-O 3.31Å
25W98.3Very high98.1Very high0 Ų052.8 Ų52.80%027%0.267CS..EExtended strand (participates in β ladder)trans-79.3139.3175.4-75.291.8000111.9T20 L22 W36 S37 Y38 Q49 L57 A123 W124 E127 L372 M377T20-W25 PolarHBondContact OG1-NE1 3.21Å; L22-W25 PolarHBondContact O-N 3.04Å; W25-W36 HydrophobicContact CB-CE3 4.01Å; W25-W36 HydrophobicContact CB-CZ3 3.99Å; W25-W36 HydrophobicContact CE3-CB 4.07Å; W25-W36 HydrophobicContact CE3-CE3 4.34Å; W25-W36 HydrophobicContact CZ3-CB 4.06Å; W25-S37 WeakPolarHBondContact CA-O 3.48Å; W25-Y38 AromaticContact CD1-CD2 3.61Å; W25-Y38 AromaticContact CD1-CE2 3.95Å; W25-Y38 AromaticContact CD2-CD2 3.83Å; W25-Y38 HydrophobicContact CD2-CD2 3.83Å; W25-Y38 AromaticContact CE2-CD2 3.48Å; W25-Y38 VanDerWaalsContact CE2-CD2 3.48Å; W25-Y38 AromaticContact CG-CD2 3.97Å; W25-Y38 HydrophobicContact CG-CD2 3.97Å; W25-Y38 HydrophobicContact CZ2-CD2 4.07Å; W25-Y38 HydrophobicContact CZ2-CG 4.45Å; W25-Y38 AromaticContact NE1-CD2 3.33Å; W25-Y38 VanDerWaalsContact NE1-CD2 3.33Å; W25-Y38 AromaticContact NE1-CE2 3.71Å; W25-Q49 PolarHBondContact O-NE2 2.85Å; W25-L57 HydrophobicContact CB-CD1 3.99Å; W25-A123 HydrophobicContact CH2-CB 4.22Å; W25-A123 HydrophobicContact CZ2-CB 3.85Å; W25-W124 AromaticContact CH2-CD1 3.29Å; W25-W124 HydrophobicContact CH2-CG 4.2Å; W25-W124 AromaticContact CH2-NE1 3.68Å; W25-W124 AromaticContact CZ3-CD1 3.7Å; W25-W124 AromaticContact CZ3-NE1 3.55Å; W25-E127 HydrophobicContact CZ2-CB 4.45Å; W25-E127 HydrophobicContact CZ2-CG 3.71Å; W25-L372 HydrophobicContact CB-CD2 3.95Å; W25-L372 HydrophobicContact CD2-CD2 3.21Å; W25-L372 HydrophobicContact CE3-CD2 3.73Å; W25-L372 HydrophobicContact CG-CD2 3.32Å; W25-L372 HydrophobicContact CH2-CD2 4.37Å; W25-L372 HydrophobicContact CZ2-CD2 4Å; W25-L372 HydrophobicContact CZ3-CD2 4.27Å; W25-M377 HydrophobicContact CH2-CE 3.45Å; W25-M377 VanDerWaalsContact CH2-CE 3.45Å; W25-M377 HydrophobicContact CZ3-CE 3.58Å
26R98.1Very high98.1Very high22 Ų2246.6 Ų46.68%0.08324%0.24CC..EExtended strand (participates in β ladder)trans-127.1133.6177-62.4-67.4177.3-81.51.1110.5S23 W36 S37 V39 P45 R47 E53S23-R26 PolarHBondContact O-NH1 2.7Å; S23-R26 PolarHBondContact O-NH2 3.43Å; R26-W36 CarbonylContact O-C 3.55Å; R26-W36 WeakPolarHBondContact O-CA 3.36Å; R26-S37 PolarHBondContact N-O 2.88Å; R26-S37 PolarHBondContact O-N 2.67Å; R26-V39 HydrophobicContact CG-CG2 4.19Å; R26-P45 VanDerWaalsContact NH2-CB 3.27Å; R26-R47 PolarHBondContact NE-O 2.93Å; R26-R47 PolarHBondContact NH2-O 3.48Å; R26-E53 WeakPolarHBondContact CA-OE1 3.47Å; R26-E53 WeakPolarHBondContact CD-OE1 3.28Å
27L98.6Very high98.1Very high1 Ų147.4 Ų47.41%0.00525%0.247CC..EExtended strand (participates in β ladder)trans-94.7128.7168.5178.161.9000108.2Q34 W36 R47 L52 E53 A96 W371L27-Q34 HydrophobicContact CD1-CB 4.14Å; L27-W36 HydrophobicContact CB-CD2 4.2Å; L27-W36 HydrophobicContact CB-CE3 4.11Å; L27-W36 HydrophobicContact CB-CH2 3.95Å; L27-W36 HydrophobicContact CB-CZ2 4.01Å; L27-W36 HydrophobicContact CB-CZ3 3.98Å; L27-W36 HydrophobicContact CD1-CD2 4.28Å; L27-W36 HydrophobicContact CD1-CG 4.4Å; L27-W36 HydrophobicContact CD1-CZ2 4.42Å; L27-W36 HydrophobicContact CD2-CZ2 4.29Å; L27-W36 HydrophobicContact CG-CZ2 4.47Å; L27-R47 PolarHBondContact O-NH2 2.79Å; L27-L52 HydrophobicContact CD2-CD2 3.88Å; L27-L52 HydrophobicContact CD2-CG 4.15Å; L27-E53 HydrophobicContact CB-CG 3.88Å; L27-E53 PolarHBondContact N-OE1 3.26Å; L27-A96 HydrophobicContact CD2-CB 4.11Å; L27-W371 HydrophobicContact CD1-CZ3 4.09Å; L27-W371 HydrophobicContact CD2-CH2 3.94Å; L27-W371 HydrophobicContact CD2-CZ3 4.05Å
28R97.9Very high98Very high169 Ų16941.6 Ų41.664%0.63822%0.218SC*.EExtended strand (participates in β ladder)trans-108.7131.1170.8-178.8179.4177.3-178.7-0.3109.3T35R28-T35 PolarHBondContact N-O 2.81Å; R28-T35 PolarHBondContact O-N 3.2Å; R28-T35 VanDerWaalsContact O-N 3.07Å
29N98.3Very high97.9Very high10 Ų1039.6 Ų39.65%0.05321%0.205CC..EExtended strand (participates in β ladder)trans-115.6131.8173.5-57.2-68.4000110.4R33 Q34 A90 E91 H94N29-R33 VanDerWaalsContact CA-O 3.3Å; N29-R33 WeakPolarHBondContact CA-O 3.31Å; N29-Q34 WeakPolarHBondContact OD1-CG 3.44Å; N29-A90 HydrophobicContact CB-CB 3.94Å; N29-E91 HydrophobicContact CB-CG 4.49Å; N29-E91 PolarHBondContact N-OE1 2.85Å; N29-E91 VanDerWaalsContact N-OE1 3.13Å; N29-E91 PolarHBondContact ND2-OE2 3.13Å; N29-H94 PolarHBondContact OD1-CE1 3.46Å
30A98.1Very high97.5Very high45 Ų4541.3 Ų41.337%0.37221%0.208SC..EExtended strand (participates in β ladder)trans-149.3112.4173.400000110.7G32 R33 D92A30-G32 PolarHBondContact O-N 3.48Å; A30-R33 PolarHBondContact N-O 3.44Å; A30-R33 VanDerWaalsContact N-O 3.09Å; A30-R33 VanDerWaalsContact O-CB 3.26Å; A30-R33 WeakPolarHBondContact O-CB 3.28Å; A30-R33 PolarHBondContact O-N 2.86Å; A30-D92 WeakPolarHBondContact CA-OD2 3.41Å; A30-D92 PolarHBondContact N-OD2 3.06Å
31E98.1Very high96.7Very high93 Ų9345.4 Ų45.444%0.43523%0.229SC..THydrogen-bonded Turntrans51.339-174.8-54-172145.600112.1R33 D92 V421 R448E31-R33 VanDerWaalsContact C-N 3.3Å; E31-R33 PolarHBondContact O-N 3.07Å; E31-D92 PolarHBondContact N-OD2 3.47Å; E31-V421 HydrophobicContact CB-CG1 4.01Å; E31-V421 HydrophobicContact CG-CG1 3.93Å; E31-R448 IonicContact OE1-CZ 3.12Å; E31-R448 IonicContact OE1-NH2 3.31Å; E31-R448 PolarHBondContact OE1-NH2 2.93Å; E31-R448 IonicContact OE2-CZ 3.2Å; E31-R448 IonicContact OE2-NH2 2.68Å; E31-R448 PolarHBondContact OE2-NH2 3.12Å
32G98.5Very high96.1Very high0 Ų050.6 Ų50.60%025%0.251CS..THydrogen-bonded Turntrans85.5-15.4-176.800000114.8A30 Q34 D92 Q386A30-G32 PolarHBondContact O-N 3.48Å; G32-Q34 PolarHBondContact O-N 3.4Å; G32-D92 PolarHBondContact N-OD2 2.83Å; G32-Q386 WeakPolarHBondContact O-CG 3.46Å; G32-Q386 PolarHBondContact O-NE2 3.42Å
33R98.8Very high95.6Very high81 Ų8156 Ų5631%0.30628%0.276SS..EExtended strand (participates in β ladder)trans-65.6120.5177.5-173.9-174.5-175.2-168.8-1.4109.8N29 A30 E31 T35 S364 D368N29-R33 VanDerWaalsContact CA-O 3.3Å; N29-R33 WeakPolarHBondContact CA-O 3.31Å; A30-R33 PolarHBondContact N-O 3.44Å; A30-R33 VanDerWaalsContact N-O 3.09Å; A30-R33 VanDerWaalsContact O-CB 3.26Å; A30-R33 WeakPolarHBondContact O-CB 3.28Å; A30-R33 PolarHBondContact O-N 2.86Å; E31-R33 VanDerWaalsContact C-N 3.3Å; E31-R33 PolarHBondContact O-N 3.07Å; R33-T35 HydrophobicContact CG-CG2 4.31Å; R33-S364 PolarHBondContact NH2-O 2.92Å; R33-D368 WeakPolarHBondContact CD-OD2 3.22Å; R33-D368 WeakPolarHBondContact CG-OD2 3.42Å; R33-D368 IonicContact CZ-OD1 2.64Å; R33-D368 VanDerWaalsContact CZ-OD1 3.29Å; R33-D368 IonicContact CZ-OD2 2.7Å; R33-D368 IonicContact NE-OD1 2.64Å; R33-D368 PolarHBondContact NE-OD1 3.22Å; R33-D368 IonicContact NE-OD2 3.99Å; R33-D368 PolarHBondContact NE-OD2 2.85Å; R33-D368 IonicContact NH2-OD1 2.96Å; R33-D368 PolarHBondContact NH2-OD1 3.13Å; R33-D368 IonicContact NH2-OD2 3.67Å
34Q98.8Very high95.2Very high7 Ų759.7 Ų59.73%0.03330%0.296CS..EExtended strand (participates in β ladder)trans-104.2123.6179.7-68.91627.800109.7L27 N29 G32 H94 A96 Q386L27-Q34 HydrophobicContact CD1-CB 4.14Å; N29-Q34 WeakPolarHBondContact OD1-CG 3.44Å; G32-Q34 PolarHBondContact O-N 3.4Å; Q34-H94 PolarHBondContact NE2-NE2 2.57Å; Q34-A96 HydrophobicContact CG-CB 4.19Å; Q34-A96 VanDerWaalsContact NE2-CA 3.31Å; Q34-A96 VanDerWaalsContact NE2-CB 3.31Å; Q34-Q386 VanDerWaalsContact NE2-CG 3.3Å
35T98.8Very high94.8Very high28 Ų2859.9 Ų59.917%0.17230%0.303CS..EExtended strand (participates in β ladder)trans-139.1134.6172610000111.5R28 R33 P367R28-T35 PolarHBondContact N-O 2.81Å; R28-T35 PolarHBondContact O-N 3.2Å; R28-T35 VanDerWaalsContact O-N 3.07Å; R33-T35 HydrophobicContact CG-CG2 4.31Å; T35-P367 HydrophobicContact CG2-CB 3.68Å
36W98.6Very high94.3Very high5 Ų565.9 Ų65.92%0.01934%0.344CS..EExtended strand (participates in β ladder)trans-91.9137.1174.7-75.394.5000110.8W25 R26 L27 E53 L57 W124 W371 L372W25-W36 HydrophobicContact CB-CE3 4.01Å; W25-W36 HydrophobicContact CB-CZ3 3.99Å; W25-W36 HydrophobicContact CE3-CB 4.07Å; W25-W36 HydrophobicContact CE3-CE3 4.34Å; W25-W36 HydrophobicContact CZ3-CB 4.06Å; R26-W36 CarbonylContact O-C 3.55Å; R26-W36 WeakPolarHBondContact O-CA 3.36Å; L27-W36 HydrophobicContact CB-CD2 4.2Å; L27-W36 HydrophobicContact CB-CE3 4.11Å; L27-W36 HydrophobicContact CB-CH2 3.95Å; L27-W36 HydrophobicContact CB-CZ2 4.01Å; L27-W36 HydrophobicContact CB-CZ3 3.98Å; L27-W36 HydrophobicContact CD1-CD2 4.28Å; L27-W36 HydrophobicContact CD1-CG 4.4Å; L27-W36 HydrophobicContact CD1-CZ2 4.42Å; L27-W36 HydrophobicContact CD2-CZ2 4.29Å; L27-W36 HydrophobicContact CG-CZ2 4.47Å; W36-E53 HydrophobicContact CH2-CB 4.4Å; W36-E53 HydrophobicContact CH2-CG 4.29Å; W36-E53 HydrophobicContact CZ3-CG 4.34Å; W36-L57 HydrophobicContact CH2-CD1 4.15Å; W36-L57 HydrophobicContact CH2-CD2 3.82Å; W36-L57 HydrophobicContact CH2-CG 3.87Å; W36-L57 HydrophobicContact CZ2-CD2 4.41Å; W36-L57 HydrophobicContact CZ3-CD1 3.99Å; W36-L57 HydrophobicContact CZ3-CD2 4Å; W36-L57 HydrophobicContact CZ3-CG 4.16Å; W36-W124 WeakPolarHBondContact O-CZ2 3.48Å; W36-W371 HydrophobicContact CZ2-CH2 4.18Å; W36-W371 HydrophobicContact CZ2-CZ2 4.17Å; W36-W371 HydrophobicContact CZ2-CZ3 4.49Å; W36-W371 AromaticContact NE1-CD2 3.53Å; W36-W371 AromaticContact NE1-CE3 3.29Å; W36-W371 VanDerWaalsContact NE1-CE3 3.29Å; W36-W371 AromaticContact NE1-CZ3 3.6Å; W36-L372 HydrophobicContact CD2-CB 3.93Å; W36-L372 HydrophobicContact CE3-CB 4.39Å; W36-L372 HydrophobicContact CG-CB 4.07Å
37S96.9Very high94.2Very high59 Ų5969.1 Ų69.141%0.41336%0.356SS..EExtended strand (participates in β ladder)trans-129147.7169.862.20000110.9W25 R26W25-S37 WeakPolarHBondContact CA-O 3.48Å; R26-S37 PolarHBondContact N-O 2.88Å; R26-S37 PolarHBondContact O-N 2.67Å
38Y97.6Very high94Very high53 Ų5376.7 Ų76.721%0.20839%0.392CS..EExtended strand (participates in β ladder)trans-101127.8172.8-173.4-104.4000108.7R24 W25 D41 A123R24-Y38 HydrophobicContact CB-CD2 4.18Å; R24-Y38 HydrophobicContact CB-CE2 3.72Å; W25-Y38 AromaticContact CD1-CD2 3.61Å; W25-Y38 AromaticContact CD1-CE2 3.95Å; W25-Y38 AromaticContact CD2-CD2 3.83Å; W25-Y38 HydrophobicContact CD2-CD2 3.83Å; W25-Y38 AromaticContact CE2-CD2 3.48Å; W25-Y38 VanDerWaalsContact CE2-CD2 3.48Å; W25-Y38 AromaticContact CG-CD2 3.97Å; W25-Y38 HydrophobicContact CG-CD2 3.97Å; W25-Y38 HydrophobicContact CZ2-CD2 4.07Å; W25-Y38 HydrophobicContact CZ2-CG 4.45Å; W25-Y38 AromaticContact NE1-CD2 3.33Å; W25-Y38 VanDerWaalsContact NE1-CD2 3.33Å; W25-Y38 AromaticContact NE1-CE2 3.71Å; Y38-D41 PolarHBondContact OH-OD1 3.05Å; Y38-A123 HydrophobicContact CD1-CB 3.7Å; Y38-A123 HydrophobicContact CD2-CB 4.08Å; Y38-A123 HydrophobicContact CE1-CB 4.35Å; Y38-A123 HydrophobicContact CG-CB 3.53Å
39V94.8Very high93.9Very high16 Ų1669.3 Ų69.310%0.09736%0.364CS..PPolyproline II helixtrans-81.5117.9171.4-177.50000107.9R24 R26 E43 P45R24-V39 HydrophobicContact CB-CB 4.5Å; R24-V39 PolarHBondContact NE-O 3.33Å; R24-V39 PolarHBondContact NH2-O 3.33Å; R24-V39 WeakPolarHBondContact O-CG2 3.46Å; R24-V39 PolarHBondContact O-N 2.76Å; R26-V39 HydrophobicContact CG-CG2 4.19Å; V39-E43 HydrophobicContact CG1-CB 3.87Å; V39-P45 HydrophobicContact CB-CG 4.47Å; V39-P45 HydrophobicContact CG1-CB 4.45Å; V39-P45 HydrophobicContact CG1-CG 4.16Å; V39-P45 HydrophobicContact CG2-CB 4.33Å
40D90Very high93.9Very high83 Ų8371.4 Ų71.444%0.44438%0.378SS..PPolyproline II helixtrans-54.7143.1-177.6-171.4-77000111.5R24 Q42 E43R24-D40 PolarHBondContact NH2-O 3.44Å; D40-Q42 PolarHBondContact O-N 3.35Å; D40-Q42 PolarHBondContact OD1-N 2.94Å; D40-E43 HydrophobicContact CB-CG 4.23Å; D40-E43 PolarHBondContact O-N 3.05Å
41D81.1Confident93.9Very high105 Ų10569.8 Ų69.856%0.56136%0.363SS*.THydrogen-bonded Turntrans-53.6-27.4-174.3-63.9-16.5000113.7R24 Y38R24-D41 WeakPolarHBondContact CD-OD1 3.4Å; R24-D41 VanDerWaalsContact CZ-CA 3.48Å; R24-D41 IonicContact NE-OD1 3.57Å; R24-D41 PolarHBondContact NH1-O 3.01Å; Y38-D41 PolarHBondContact OH-OD1 3.05Å
42Q85Confident93.9Very high185 Ų18565.8 Ų65.886%0.86434%0.344SS*.THydrogen-bonded Turntrans-83.8-15.3178.7-57.5-176.513.200114D40D40-Q42 PolarHBondContact O-N 3.35Å; D40-Q42 PolarHBondContact OD1-N 2.94Å
43E88.6Confident93.9Very high123 Ų12365.8 Ų65.858%0.57534%0.344SS*.SBendtrans-92.7157.3-179-65.3-175165.400111.9R24 V39 D40R24-E43 PolarHBondContact NH2-O 3.31Å; V39-E43 HydrophobicContact CG1-CB 3.87Å; D40-E43 HydrophobicContact CB-CG 4.23Å; D40-E43 PolarHBondContact O-N 3.05Å
44T85.9Confident93.9Very high131 Ų13162 Ų6280%0.80433%0.33SS*.PPolyproline II helixtrans-95.4129.2170-57.10000108.8S46T44-S46 PolarHBondContact O-N 2.97Å
45P89.3Confident93.9Very high42 Ų4263.2 Ų63.227%0.27334%0.336SS..PPolyproline II helixtrans-56.4132.5176.3-24.132.9000112R26 V39 R47R26-P45 VanDerWaalsContact NH2-CB 3.27Å; V39-P45 HydrophobicContact CB-CG 4.47Å; V39-P45 HydrophobicContact CG1-CB 4.45Å; V39-P45 HydrophobicContact CG1-CG 4.16Å; V39-P45 HydrophobicContact CG2-CB 4.33Å; P45-R47 PolarHBondContact O-N 2.87Å
46S88.5Confident93.9Very high125 Ų12562.5 Ų62.587%0.87433%0.332SS*.SBendtrans-67-19.8-178.658.80000114T44T44-S46 PolarHBondContact O-N 2.97Å
47R95.1Very high93.9Very high90 Ų9062.2 Ų62.234%0.3433%0.331SS..SBendtrans-147.6159172.863.4168.6-179.473.2-3.5111.8R26 L27 P45 E53R26-R47 PolarHBondContact NE-O 2.93Å; R26-R47 PolarHBondContact NH2-O 3.48Å; L27-R47 PolarHBondContact O-NH2 2.79Å; P45-R47 PolarHBondContact O-N 2.87Å; R47-E53 IonicContact CZ-OE1 3.62Å; R47-E53 VanDerWaalsContact CZ-OE1 3.29Å; R47-E53 IonicContact CZ-OE2 3.66Å; R47-E53 VanDerWaalsContact NH1-CD 3.32Å; R47-E53 IonicContact NH1-OE1 3.83Å; R47-E53 PolarHBondContact NH1-OE1 3.2Å; R47-E53 VanDerWaalsContact NH1-OE1 3.09Å; R47-E53 IonicContact NH1-OE2 3.78Å; R47-E53 PolarHBondContact NH1-OE2 3.41Å; R47-E53 IonicContact NH2-OE1 2.79Å; R47-E53 PolarHBondContact NH2-OE1 2.96Å; R47-E53 IonicContact NH2-OE2 2.72Å
48E94.7Very high93.9Very high160 Ų16060.3 Ų60.375%0.74832%0.32SS*.PPolyproline II helixtrans-61.3153.9167.6-64.5-16917100111.2
49Q96.5Very high94Very high14 Ų1460.1 Ų60.17%0.06532%0.323CS..PPolyproline II helixtrans-73.7136.1175.1-167.9172.951.800109.7L22 W25 E53 L57 R63 F64L22-Q49 PolarHBondContact O-NE2 2.68Å; W25-Q49 PolarHBondContact O-NE2 2.85Å; Q49-E53 WeakPolarHBondContact CA-OE2 3.27Å; Q49-E53 HydrophobicContact CG-CB 3.45Å; Q49-E53 VanDerWaalsContact CG-CB 3.45Å; Q49-E53 HydrophobicContact CG-CG 4.37Å; Q49-E53 WeakPolarHBondContact CG-OE2 3.5Å; Q49-L57 VanDerWaalsContact NE2-CD1 3.35Å; Q49-R63 PolarHBondContact O-NH2 2.8Å; Q49-R63 VanDerWaalsContact O-NH2 3.16Å; Q49-F64 WeakPolarHBondContact O-CZ 3.32Å
50T97.8Very high94.1Very high55 Ų5564.8 Ų64.834%0.33735%0.347SS..PPolyproline II helixtrans-82.8171-179.867.60000111.9E53 A54 F64T50-E53 PolarHBondContact N-OE2 3.31Å; T50-E53 PolarHBondContact O-N 3Å; T50-E53 WeakPolarHBondContact OG1-CG 3.37Å; T50-E53 PolarHBondContact OG1-N 3.44Å; T50-E53 PolarHBondContact OG1-OE2 3.02Å; T50-A54 WeakPolarHBondContact O-CB 3.34Å; T50-A54 PolarHBondContact O-N 3.42Å; T50-F64 VanDerWaalsContact C-CZ 3.42Å
51M98.1Very high94.4Very high10 Ų1061.8 Ų61.85%0.04933%0.331CS..Hα-helixtrans-63.8-40.8172.3-176173.1164.100111.8E53 A54 H55 I61 F64 V65 F84 R87 L88M51-E53 VanDerWaalsContact C-N 3.32Å; M51-E53 PolarHBondContact O-N 3.02Å; M51-A54 PolarHBondContact O-N 3.48Å; M51-H55 VanDerWaalsContact O-CB 3.23Å; M51-H55 WeakPolarHBondContact O-CB 3.5Å; M51-H55 PolarHBondContact O-N 3.47Å; M51-I61 HydrophobicContact CE-CD1 4.19Å; M51-F64 HydrophobicContact CB-CB 3.87Å; M51-F64 HydrophobicContact CB-CD1 3.92Å; M51-F64 HydrophobicContact CB-CD2 3.8Å; M51-F64 HydrophobicContact CB-CE1 4.33Å; M51-F64 HydrophobicContact CB-CE2 4.2Å; M51-F64 HydrophobicContact CB-CG 3.62Å; M51-F64 HydrophobicContact CB-CZ 4.42Å; M51-F64 HydrophobicContact CG-CB 3.77Å; M51-F64 HydrophobicContact CG-CD2 3.97Å; M51-F64 HydrophobicContact CG-CG 3.95Å; M51-F64 HydrophobicContact SD-CB 3.56Å; M51-F64 VanDerWaalsContact SD-CB 3.56Å; M51-F64 HydrophobicContact SD-CG 4.36Å; M51-V65 HydrophobicContact CE-CB 4.12Å; M51-V65 HydrophobicContact CE-CG1 3.62Å; M51-V65 HydrophobicContact SD-CB 4.44Å; M51-V65 HydrophobicContact SD-CG1 4.34Å; M51-F84 HydrophobicContact CE-CD2 3.81Å; M51-F84 HydrophobicContact CE-CE2 3.44Å; M51-F84 VanDerWaalsContact CE-CE2 3.44Å; M51-F84 HydrophobicContact CE-CZ 4.04Å; M51-R87 HydrophobicContact CE-CB 4.09Å; M51-R87 HydrophobicContact SD-CB 3.39Å; M51-R87 WeakPolarHBondContact SD-CB 3.43Å; M51-R87 VanDerWaalsContact SD-CD 3.57Å; M51-R87 HydrophobicContact SD-CG 4.12Å; M51-L88 HydrophobicContact CE-CD2 4.23Å; M51-L88 HydrophobicContact CG-CD2 4.22Å
52L98.6Very high95.1Very high9 Ų960.1 Ų60.15%0.04733%0.327CS..Hα-helixtrans-56.6-46175.917258.2000111.4L27 S56 L88 A90 A96L27-L52 HydrophobicContact CD2-CD2 3.88Å; L27-L52 HydrophobicContact CD2-CG 4.15Å; L52-S56 VanDerWaalsContact O-CB 3.28Å; L52-S56 WeakPolarHBondContact O-CB 3.25Å; L52-S56 PolarHBondContact O-N 2.96Å; L52-S56 PolarHBondContact O-OG 2.99Å; L52-L88 HydrophobicContact CD1-CB 4.4Å; L52-A90 HydrophobicContact CD2-CB 4.24Å; L52-A96 HydrophobicContact CD1-CB 4.46Å; L52-A96 HydrophobicContact CD2-CB 4.25Å
53E98.7Very high95.6Very high1 Ų158.3 Ų58.31%0.00531%0.313CS..Hα-helixtrans-65.9-49.2177.5-69.9167.5148.800111.5R26 L27 W36 R47 Q49 T50 M51 H55 S56 L57R26-E53 WeakPolarHBondContact CA-OE1 3.47Å; R26-E53 WeakPolarHBondContact CD-OE1 3.28Å; L27-E53 HydrophobicContact CB-CG 3.88Å; L27-E53 PolarHBondContact N-OE1 3.26Å; W36-E53 HydrophobicContact CH2-CB 4.4Å; W36-E53 HydrophobicContact CH2-CG 4.29Å; W36-E53 HydrophobicContact CZ3-CG 4.34Å; R47-E53 IonicContact CZ-OE1 3.62Å; R47-E53 VanDerWaalsContact CZ-OE1 3.29Å; R47-E53 IonicContact CZ-OE2 3.66Å; R47-E53 VanDerWaalsContact NH1-CD 3.32Å; R47-E53 IonicContact NH1-OE1 3.83Å; R47-E53 PolarHBondContact NH1-OE1 3.2Å; R47-E53 VanDerWaalsContact NH1-OE1 3.09Å; R47-E53 IonicContact NH1-OE2 3.78Å; R47-E53 PolarHBondContact NH1-OE2 3.41Å; R47-E53 IonicContact NH2-OE1 2.79Å; R47-E53 PolarHBondContact NH2-OE1 2.96Å; R47-E53 IonicContact NH2-OE2 2.72Å; Q49-E53 WeakPolarHBondContact CA-OE2 3.27Å; Q49-E53 HydrophobicContact CG-CB 3.45Å; Q49-E53 VanDerWaalsContact CG-CB 3.45Å; Q49-E53 HydrophobicContact CG-CG 4.37Å; Q49-E53 WeakPolarHBondContact CG-OE2 3.5Å; T50-E53 PolarHBondContact N-OE2 3.31Å; T50-E53 PolarHBondContact O-N 3Å; T50-E53 WeakPolarHBondContact OG1-CG 3.37Å; T50-E53 PolarHBondContact OG1-N 3.44Å; T50-E53 PolarHBondContact OG1-OE2 3.02Å; M51-E53 VanDerWaalsContact C-N 3.32Å; M51-E53 PolarHBondContact O-N 3.02Å; E53-H55 VanDerWaalsContact C-N 3.32Å; E53-H55 PolarHBondContact O-N 3.04Å; E53-S56 PolarHBondContact O-N 3.15Å; E53-L57 WeakPolarHBondContact O-CB 3.45Å; E53-L57 WeakPolarHBondContact O-CG 3.49Å; E53-L57 PolarHBondContact O-N 3.33Å; E53-L57 VanDerWaalsContact O-N 3.08Å
54A98.6Very high96Very high1 Ų154.9 Ų54.91%0.00830%0.296CS..Hα-helixtrans-60-42.4179.500000112.1T50 M51 L57 G58 L59 I61 F64T50-A54 WeakPolarHBondContact O-CB 3.34Å; T50-A54 PolarHBondContact O-N 3.42Å; M51-A54 PolarHBondContact O-N 3.48Å; A54-L57 PolarHBondContact O-N 2.92Å; A54-G58 PolarHBondContact O-N 3.48Å; A54-G58 VanDerWaalsContact O-N 3.11Å; A54-L59 HydrophobicContact CB-CB 4.07Å; A54-L59 PolarHBondContact O-N 2.99Å; A54-I61 HydrophobicContact CB-CG2 3.9Å; A54-F64 HydrophobicContact CB-CE2 3.82Å
55H98.6Very high96.4Very high32 Ų3249.6 Ų49.615%0.14826%0.263CS..Hα-helixtrans-64.2-48.1176.5179.6-97.5000112M51 E53 L57 G58 I61 F84 L88 D687 R709M51-H55 VanDerWaalsContact O-CB 3.23Å; M51-H55 WeakPolarHBondContact O-CB 3.5Å; M51-H55 PolarHBondContact O-N 3.47Å; E53-H55 VanDerWaalsContact C-N 3.32Å; E53-H55 PolarHBondContact O-N 3.04Å; H55-L57 PolarHBondContact O-N 3.07Å; H55-G58 PolarHBondContact O-N 3.38Å; H55-I61 HydrophobicContact CB-CG2 4.26Å; H55-F84 AromaticContact CD2-CZ 3.8Å; H55-F84 AromaticContact NE2-CZ 3.74Å; H55-L88 HydrophobicContact CB-CD2 3.79Å; H55-D687 IonicContact CD2-OD2 2.83Å; H55-D687 IonicContact CE1-OD2 3.86Å; H55-D687 IonicContact NE2-OD2 3.07Å; H55-D687 PolarHBondContact NE2-OD2 3.33Å; H55-R709 PolarHBondContact CE1-NH2 2.8Å
56S98.5Very high96.6Very high13 Ų1352 Ų529%0.09128%0.282CS..Hα-helixtrans-59.6-31.8179.7-60.10000112.8L52 E53 G373L52-S56 VanDerWaalsContact O-CB 3.28Å; L52-S56 WeakPolarHBondContact O-CB 3.25Å; L52-S56 PolarHBondContact O-N 2.96Å; L52-S56 PolarHBondContact O-OG 2.99Å; E53-S56 PolarHBondContact O-N 3.15Å; S56-G373 CarbonylContact O-C 3.58Å
57L98.7Very high96.8Very high0 Ų051.5 Ų51.50%027%0.269CS..THydrogen-bonded Turntrans-93-4-179.2-58.8175.1000113.5L22 W25 W36 Q49 E53 A54 H55 L59 L372L22-L57 HydrophobicContact CB-CD1 4.48Å; L22-L57 HydrophobicContact CD1-CB 4.48Å; L22-L57 VanDerWaalsContact O-CD1 3.3Å; L22-L57 WeakPolarHBondContact O-CD1 3.29Å; W25-L57 HydrophobicContact CB-CD1 3.99Å; W36-L57 HydrophobicContact CH2-CD1 4.15Å; W36-L57 HydrophobicContact CH2-CD2 3.82Å; W36-L57 HydrophobicContact CH2-CG 3.87Å; W36-L57 HydrophobicContact CZ2-CD2 4.41Å; W36-L57 HydrophobicContact CZ3-CD1 3.99Å; W36-L57 HydrophobicContact CZ3-CD2 4Å; W36-L57 HydrophobicContact CZ3-CG 4.16Å; Q49-L57 VanDerWaalsContact NE2-CD1 3.35Å; E53-L57 WeakPolarHBondContact O-CB 3.45Å; E53-L57 WeakPolarHBondContact O-CG 3.49Å; E53-L57 PolarHBondContact O-N 3.33Å; E53-L57 VanDerWaalsContact O-N 3.08Å; A54-L57 PolarHBondContact O-N 2.92Å; H55-L57 PolarHBondContact O-N 3.07Å; L57-L59 VanDerWaalsContact C-N 3.3Å; L57-L59 HydrophobicContact CB-CD1 4.36Å; L57-L59 HydrophobicContact CB-CG 4.2Å; L57-L59 HydrophobicContact CD1-CD1 4.37Å; L57-L59 PolarHBondContact O-N 3.19Å; L57-L372 HydrophobicContact CD2-CB 4.03Å; L57-L372 HydrophobicContact CD2-CD2 3.37Å; L57-L372 HydrophobicContact CD2-CG 3.39Å
58G98Very high96.8Very high18 Ų1849.3 Ų49.319%0.18627%0.268CS..THydrogen-bonded Turntrans68.726.6-177.500000113.9K15 A54 H55K15-G58 WeakPolarHBondContact CE-O 3.45Å; K15-G58 PolarHBondContact NZ-O 2.89Å; A54-G58 PolarHBondContact O-N 3.48Å; A54-G58 VanDerWaalsContact O-N 3.11Å; H55-G58 PolarHBondContact O-N 3.38Å
59L98.3Very high96.7Very high50 Ų5046.1 Ų46.126%0.26226%0.263SS..  trans-77.1163.7170.9-66.3174.4000110.7L22 A54 L57 I61L22-L59 HydrophobicContact CB-CD1 4.09Å; L22-L59 HydrophobicContact CB-CD2 3.97Å; L22-L59 HydrophobicContact CB-CG 4.24Å; L22-L59 HydrophobicContact CD1-CD2 4.24Å; A54-L59 HydrophobicContact CB-CB 4.07Å; A54-L59 PolarHBondContact O-N 2.99Å; L57-L59 VanDerWaalsContact C-N 3.3Å; L57-L59 HydrophobicContact CB-CD1 4.36Å; L57-L59 HydrophobicContact CB-CG 4.2Å; L57-L59 HydrophobicContact CD1-CD1 4.37Å; L57-L59 PolarHBondContact O-N 3.19Å; L59-I61 PolarHBondContact O-N 3.23Å
60D96.9Very high96.7Very high114 Ų11448.7 Ų48.761%0.6129%0.286SS*.  trans-64.6129.9174179.727.2000110.6S62D60-S62 VanDerWaalsContact CG-OG 3.3Å; D60-S62 VanDerWaalsContact OD1-CB 3.28Å; D60-S62 WeakPolarHBondContact OD1-CB 3.3Å; D60-S62 PolarHBondContact OD1-N 3.09Å; D60-S62 PolarHBondContact OD1-OG 2.94Å; D60-S62 PolarHBondContact OD2-OG 3.14Å
61I97.6Very high96.6Very high20 Ų2046.8 Ų46.810%0.10328%0.276CS..  trans-109.64.7-179.159.7170.8000112.8M51 A54 H55 L59 R63 F64 V65 F84M51-I61 HydrophobicContact CE-CD1 4.19Å; A54-I61 HydrophobicContact CB-CG2 3.9Å; H55-I61 HydrophobicContact CB-CG2 4.26Å; L59-I61 PolarHBondContact O-N 3.23Å; I61-R63 PolarHBondContact O-N 2.97Å; I61-R63 VanDerWaalsContact O-N 3.08Å; I61-F64 HydrophobicContact CB-CD2 4.27Å; I61-F64 HydrophobicContact CG2-CD2 4.47Å; I61-F64 PolarHBondContact O-N 3.15Å; I61-V65 HydrophobicContact CD1-CG1 3.86Å; I61-V65 HydrophobicContact CG1-CG1 4.12Å; I61-V65 PolarHBondContact O-N 3.41Å; I61-V65 VanDerWaalsContact O-N 3.13Å; I61-F84 HydrophobicContact CD1-CE2 3.87Å; I61-F84 HydrophobicContact CD1-CZ 4.38Å
62S95.6Very high96.4Very high70 Ų7054.1 Ų54.149%0.4931%0.309SS..THydrogen-bonded Turntrans-54.3-29.9-178.4690000113.7D60 F64 V65D60-S62 VanDerWaalsContact CG-OG 3.3Å; D60-S62 VanDerWaalsContact OD1-CB 3.28Å; D60-S62 WeakPolarHBondContact OD1-CB 3.3Å; D60-S62 PolarHBondContact OD1-N 3.09Å; D60-S62 PolarHBondContact OD1-OG 2.94Å; D60-S62 PolarHBondContact OD2-OG 3.14Å; S62-F64 VanDerWaalsContact C-N 3.27Å; S62-F64 PolarHBondContact O-N 3.35Å; S62-V65 WeakPolarHBondContact CA-O 3.48Å
63R95.3Very high96.3Very high146 Ų14655.2 Ų55.255%0.55132%0.317SS*.THydrogen-bonded Turntrans-67.6-22.4174.972176.2-179.8173-2.9114.3Q49 I61Q49-R63 PolarHBondContact O-NH2 2.8Å; Q49-R63 VanDerWaalsContact O-NH2 3.16Å; I61-R63 PolarHBondContact O-N 2.97Å; I61-R63 VanDerWaalsContact O-N 3.08Å
64F96Very high96.3Very high51 Ų5155.2 Ų55.222%0.22432%0.317CS..THydrogen-bonded Turntrans-102.1-36.7-177-58.2-72.8000112.7Q49 T50 M51 A54 I61 S62 R87Q49-F64 WeakPolarHBondContact O-CZ 3.32Å; T50-F64 VanDerWaalsContact C-CZ 3.42Å; M51-F64 HydrophobicContact CB-CB 3.87Å; M51-F64 HydrophobicContact CB-CD1 3.92Å; M51-F64 HydrophobicContact CB-CD2 3.8Å; M51-F64 HydrophobicContact CB-CE1 4.33Å; M51-F64 HydrophobicContact CB-CE2 4.2Å; M51-F64 HydrophobicContact CB-CG 3.62Å; M51-F64 HydrophobicContact CB-CZ 4.42Å; M51-F64 HydrophobicContact CG-CB 3.77Å; M51-F64 HydrophobicContact CG-CD2 3.97Å; M51-F64 HydrophobicContact CG-CG 3.95Å; M51-F64 HydrophobicContact SD-CB 3.56Å; M51-F64 VanDerWaalsContact SD-CB 3.56Å; M51-F64 HydrophobicContact SD-CG 4.36Å; A54-F64 HydrophobicContact CB-CE2 3.82Å; I61-F64 HydrophobicContact CB-CD2 4.27Å; I61-F64 HydrophobicContact CG2-CD2 4.47Å; I61-F64 PolarHBondContact O-N 3.15Å; S62-F64 VanDerWaalsContact C-N 3.27Å; S62-F64 PolarHBondContact O-N 3.35Å; F64-R87 PolarHBondContact O-NH1 3.12Å
65V95Very high96.2Very high20 Ų2058.5 Ų58.512%0.12133%0.334CS..SBendtrans-138.2123.2-179.562.70000108.7M51 I61 S62 F84 N685M51-V65 HydrophobicContact CE-CB 4.12Å; M51-V65 HydrophobicContact CE-CG1 3.62Å; M51-V65 HydrophobicContact SD-CB 4.44Å; M51-V65 HydrophobicContact SD-CG1 4.34Å; I61-V65 HydrophobicContact CD1-CG1 3.86Å; I61-V65 HydrophobicContact CG1-CG1 4.12Å; I61-V65 PolarHBondContact O-N 3.41Å; I61-V65 VanDerWaalsContact O-N 3.13Å; S62-V65 WeakPolarHBondContact CA-O 3.48Å; V65-F84 HydrophobicContact CG1-CD2 4.3Å; V65-F84 HydrophobicContact CG1-CE2 4.25Å; V65-F84 HydrophobicContact CG2-CD2 4.46Å; V65-N685 HydrophobicContact CG1-CB 4.13Å; V65-N685 HydrophobicContact CG2-CB 4.13Å
66S92.8Very high96.1Very high94 Ų9459.8 Ų59.866%0.65734%0.342SS*.  trans-87.5147.5175.356.30000110.5
67D94.6Very high96.1Very high113 Ų11359.1 Ų59.160%0.60434%0.337SS*.  trans-58.8142.1169.1-72.6-15.7000111.2L684D67-L684 HydrophobicContact CB-CB 3.85Å; D67-L684 HydrophobicContact CB-CD1 4.43Å
68S93.4Very high96.1Very high45 Ų4559.3 Ų59.332%0.31534%0.339SS..  trans-115.6175.9173.972.20000110.4K80 L684S68-K80 WeakPolarHBondContact OG-CD 3.49Å; S68-K80 WeakPolarHBondContact OG-CE 3.37Å; S68-L684 PolarHBondContact N-O 3.39Å; S68-L684 PolarHBondContact OG-O 3.06Å
69S94.2Very high96.1Very high92 Ų9260.1 Ų60.164%0.64334%0.343SS*.PPolyproline II helixtrans-63.2154.2171.261.30000110.6K80S69-K80 PolarHBondContact O-NZ 2.81Å
70A95.8Very high96.1Very high68 Ų6859.1 Ų59.156%0.56234%0.337SS*.PPolyproline II helixtrans-54.4144.3171.200000110.7L684A70-L684 HydrophobicContact CB-CD2 4.33Å
71S95.4Very high96.2Very high16 Ų1653.7 Ų53.711%0.11231%0.308CS..PPolyproline II helixtrans-76.6139174.8-79.10000111.5D76 K80 V679 Q682S71-D76 VanDerWaalsContact CA-OD2 3.32Å; S71-D76 WeakPolarHBondContact CA-OD2 3.34Å; S71-D76 WeakPolarHBondContact CB-OD2 3.36Å; S71-D76 PolarHBondContact OG-OD2 2.85Å; S71-K80 WeakPolarHBondContact OG-CD 3.42Å; S71-K80 PolarHBondContact OG-NZ 3.48Å; S71-V679 WeakPolarHBondContact O-CG1 3.27Å; S71-Q682 PolarHBondContact OG-OE1 3.25Å
72E93.7Very high96.3Very high163 Ų16353.3 Ų53.376%0.76231%0.306SS*.  trans-108.4-15.9179.2-62.1-176.8169.600112.3
73T97.2Very high96.4Very high33 Ų3352.7 Ų52.720%0.20230%0.297CS..SBendtrans-136.5156.4-174.6690000111L75 D76 A77 L729T73-L75 VanDerWaalsContact C-N 3.33Å; T73-L75 PolarHBondContact O-N 3.37Å; T73-D76 PolarHBondContact O-N 3.23Å; T73-D76 WeakPolarHBondContact OG1-CB 3.41Å; T73-D76 PolarHBondContact OG1-N 3.02Å; T73-A77 WeakPolarHBondContact O-CB 3.38Å; T73-A77 PolarHBondContact O-N 3.24Å; T73-L729 CarbonylContact C-O 3.54Å; T73-L729 WeakPolarHBondContact CA-O 3.42Å; T73-L729 WeakPolarHBondContact CB-O 3.28Å
74A97.9Very high96.5Very high0 Ų045.8 Ų45.80%027%0.271CS..Hα-helixtrans-62.9-37.6177.900000112.5A77 A78 V675 L717 F720 C721 L729A74-A77 PolarHBondContact O-N 3Å; A74-A78 VanDerWaalsContact O-CB 3.28Å; A74-A78 WeakPolarHBondContact O-CB 3.47Å; A74-A78 PolarHBondContact O-N 3.09Å; A74-V675 HydrophobicContact CB-CG1 3.78Å; A74-L717 HydrophobicContact CB-CB 4.3Å; A74-L717 HydrophobicContact CB-CD2 3.8Å; A74-F720 HydrophobicContact CB-CD1 3.79Å; A74-F720 HydrophobicContact CB-CE1 4.33Å; A74-C721 VanDerWaalsContact CB-SG 3.54Å; A74-L729 PolarHBondContact N-O 3.4Å
75L97.1Very high96.7Very high71 Ų7143.7 Ų43.737%0.37226%0.262SS..Hα-helixtrans-64.1-45.9177.1179.764.6000111.7T73 A78 A79 C721 A730T73-L75 VanDerWaalsContact C-N 3.33Å; T73-L75 PolarHBondContact O-N 3.37Å; L75-A78 PolarHBondContact O-N 2.89Å; L75-A79 WeakPolarHBondContact O-CB 3.34Å; L75-A79 PolarHBondContact O-N 3.34Å; L75-C721 PolarHBondContact N-SG 3.15Å; L75-A730 WeakPolarHBondContact CB-O 3.2Å; L75-A730 PolarHBondContact N-O 3.47Å; L75-A730 VanDerWaalsContact N-O 3.12Å
76D97.1Very high96.8Very high58 Ų5846.4 Ų46.431%0.3127%0.27SS..Hα-helixtrans-64.1-45177.6-178.553.2000111.1S71 T73 A78 A79 K80S71-D76 VanDerWaalsContact CA-OD2 3.32Å; S71-D76 WeakPolarHBondContact CA-OD2 3.34Å; S71-D76 WeakPolarHBondContact CB-OD2 3.36Å; S71-D76 PolarHBondContact OG-OD2 2.85Å; T73-D76 PolarHBondContact O-N 3.23Å; T73-D76 WeakPolarHBondContact OG1-CB 3.41Å; T73-D76 PolarHBondContact OG1-N 3.02Å; D76-A78 PolarHBondContact O-N 3.47Å; D76-A79 PolarHBondContact O-N 3.09Å; D76-K80 WeakPolarHBondContact O-CG 3.47Å; D76-K80 PolarHBondContact O-N 3.15Å; D76-K80 VanDerWaalsContact OD1-CE 3.31Å; D76-K80 WeakPolarHBondContact OD1-CE 3.39Å; D76-K80 IonicContact OD1-NZ 3.36Å; D76-K80 VanDerWaalsContact OD2-CE 3.26Å; D76-K80 WeakPolarHBondContact OD2-CE 3.4Å; D76-K80 IonicContact OD2-NZ 3.81Å; D76-K80 PolarHBondContact OD2-NZ 3.49Å
77A98.4Very high97.1Very high0 Ų047.8 Ų47.80%026%0.261CS..Hα-helixtrans-63-43.617800000112.4T73 A74 K80 G81 V679 Q682 L717T73-A77 WeakPolarHBondContact O-CB 3.38Å; T73-A77 PolarHBondContact O-N 3.24Å; A74-A77 PolarHBondContact O-N 3Å; A77-K80 PolarHBondContact O-N 2.75Å; A77-G81 PolarHBondContact O-N 2.76Å; A77-V679 HydrophobicContact CB-CG2 3.99Å; A77-Q682 VanDerWaalsContact CA-OE1 3.22Å; A77-Q682 VanDerWaalsContact CB-OE1 3.3Å; A77-Q682 PolarHBondContact O-NE2 2.66Å; A77-L717 HydrophobicContact CB-CD1 3.7Å
78A98.5Very high97.3Very high3 Ų342.8 Ų42.83%0.02523%0.234CC..Hα-helixtrans-62-43.517500000111.7A74 L75 D76 G81 M82 A400 L717A74-A78 VanDerWaalsContact O-CB 3.28Å; A74-A78 WeakPolarHBondContact O-CB 3.47Å; A74-A78 PolarHBondContact O-N 3.09Å; L75-A78 PolarHBondContact O-N 2.89Å; D76-A78 PolarHBondContact O-N 3.47Å; A78-G81 PolarHBondContact O-N 2.88Å; A78-M82 WeakPolarHBondContact O-CG 3.38Å; A78-M82 PolarHBondContact O-N 3.27Å; A78-A400 HydrophobicContact CB-CB 4.38Å; A78-L717 HydrophobicContact CB-CB 3.94Å
79A97.8Very high97.5Very high35 Ų3542 Ų4229%0.28923%0.225SC..Hα-helixtrans-63.7-44.2178.100000112.2L75 D76 M82 N83L75-A79 WeakPolarHBondContact O-CB 3.34Å; L75-A79 PolarHBondContact O-N 3.34Å; D76-A79 PolarHBondContact O-N 3.09Å; A79-M82 PolarHBondContact O-N 2.91Å; A79-N83 WeakPolarHBondContact O-CB 3.49Å; A79-N83 PolarHBondContact O-N 3.46Å; A79-N83 PolarHBondContact O-ND2 3.26Å
80K98.3Very high97.7Very high30 Ų3037.9 Ų37.913%0.1320%0.196CC..Hα-helixtrans-64.3-41.5174.5-72.2-179-168158.60111.9S68 S69 S71 D76 A77 N83 F84S68-K80 WeakPolarHBondContact OG-CD 3.49Å; S68-K80 WeakPolarHBondContact OG-CE 3.37Å; S69-K80 PolarHBondContact O-NZ 2.81Å; S71-K80 WeakPolarHBondContact OG-CD 3.42Å; S71-K80 PolarHBondContact OG-NZ 3.48Å; D76-K80 WeakPolarHBondContact O-CG 3.47Å; D76-K80 PolarHBondContact O-N 3.15Å; D76-K80 VanDerWaalsContact OD1-CE 3.31Å; D76-K80 WeakPolarHBondContact OD1-CE 3.39Å; D76-K80 IonicContact OD1-NZ 3.36Å; D76-K80 VanDerWaalsContact OD2-CE 3.26Å; D76-K80 WeakPolarHBondContact OD2-CE 3.4Å; D76-K80 IonicContact OD2-NZ 3.81Å; D76-K80 PolarHBondContact OD2-NZ 3.49Å; A77-K80 PolarHBondContact O-N 2.75Å; K80-N83 PolarHBondContact O-N 2.97Å; K80-F84 WeakPolarHBondContact O-CB 3.37Å; K80-F84 PolarHBondContact O-N 3.44Å
81G98.6Very high97.8Very high0 Ų040.3 Ų40.30%020%0.196CC..Hα-helixtrans-57.4-50.1174.700000112.5A77 A78 N83 F84 Y85 G686 I714A77-G81 PolarHBondContact O-N 2.76Å; A78-G81 PolarHBondContact O-N 2.88Å; G81-N83 VanDerWaalsContact C-N 3.34Å; G81-N83 PolarHBondContact O-N 3.42Å; G81-F84 PolarHBondContact O-N 3.43Å; G81-Y85 VanDerWaalsContact O-CB 3.27Å; G81-Y85 WeakPolarHBondContact O-CB 3.32Å; G81-Y85 PolarHBondContact O-N 3.33Å; G81-G686 WeakPolarHBondContact CA-O 3.4Å; G81-I714 VanDerWaalsContact C-CD1 3.48Å
82M98.6Very high97.9Very high12 Ų1241.2 Ų41.26%0.05920%0.2CC..Hα-helixtrans-61.6-41.4175.7-71.2-172.7-69.300112.2A78 A79 Y85 R86 F397 A400 A402 L408 I714A78-M82 WeakPolarHBondContact O-CG 3.38Å; A78-M82 PolarHBondContact O-N 3.27Å; A79-M82 PolarHBondContact O-N 2.91Å; M82-Y85 PolarHBondContact O-N 3.25Å; M82-R86 WeakPolarHBondContact O-CB 3.35Å; M82-R86 VanDerWaalsContact O-CG 3.28Å; M82-R86 WeakPolarHBondContact O-CG 3.36Å; M82-R86 PolarHBondContact O-N 2.91Å; M82-F397 HydrophobicContact CB-CE1 4.45Å; M82-F397 HydrophobicContact CB-CE2 4.38Å; M82-F397 HydrophobicContact CB-CZ 4.21Å; M82-F397 HydrophobicContact CG-CD1 4.07Å; M82-F397 HydrophobicContact CG-CD2 4.49Å; M82-F397 HydrophobicContact CG-CE1 4.03Å; M82-F397 HydrophobicContact CG-CE2 4.47Å; M82-F397 HydrophobicContact CG-CG 4.3Å; M82-F397 HydrophobicContact CG-CZ 4.25Å; M82-F397 HydrophobicContact SD-CG 4.31Å; M82-A400 HydrophobicContact CE-CB 3.74Å; M82-A400 HydrophobicContact CG-CB 4.41Å; M82-A400 HydrophobicContact SD-CB 3.54Å; M82-A400 VanDerWaalsContact SD-CB 3.54Å; M82-A402 HydrophobicContact SD-CB 3.82Å; M82-L408 HydrophobicContact CB-CD1 4.06Å; M82-L408 HydrophobicContact CE-CD1 4.19Å; M82-L408 HydrophobicContact SD-CD1 3.92Å; M82-I714 HydrophobicContact CG-CD1 4.29Å; M82-I714 HydrophobicContact CG-CG1 4.46Å; M82-I714 HydrophobicContact CG-CG2 3.6Å; M82-I714 HydrophobicContact SD-CG2 4.33Å
83N98Very high98.1Very high57 Ų5733.5 Ų33.531%0.30516%0.164SC..Hα-helixtrans-67.8-33179.4-82.7-63.4000113.6A79 K80 G81 R86A79-N83 WeakPolarHBondContact O-CB 3.49Å; A79-N83 PolarHBondContact O-N 3.46Å; A79-N83 PolarHBondContact O-ND2 3.26Å; K80-N83 PolarHBondContact O-N 2.97Å; G81-N83 VanDerWaalsContact C-N 3.34Å; G81-N83 PolarHBondContact O-N 3.42Å; N83-R86 WeakPolarHBondContact O-CG 3.4Å
84F98.6Very high98.2Very high1 Ų131.9 Ų31.90%0.00415%0.154CC..Hα-helixtrans-70.3-57.7170.3176.2-93.9000110.3M51 H55 I61 V65 K80 G81 R86 R87 L88 N685 D687M51-F84 HydrophobicContact CE-CD2 3.81Å; M51-F84 HydrophobicContact CE-CE2 3.44Å; M51-F84 VanDerWaalsContact CE-CE2 3.44Å; M51-F84 HydrophobicContact CE-CZ 4.04Å; H55-F84 AromaticContact CD2-CZ 3.8Å; H55-F84 AromaticContact NE2-CZ 3.74Å; I61-F84 HydrophobicContact CD1-CE2 3.87Å; I61-F84 HydrophobicContact CD1-CZ 4.38Å; V65-F84 HydrophobicContact CG1-CD2 4.3Å; V65-F84 HydrophobicContact CG1-CE2 4.25Å; V65-F84 HydrophobicContact CG2-CD2 4.46Å; K80-F84 WeakPolarHBondContact O-CB 3.37Å; K80-F84 PolarHBondContact O-N 3.44Å; G81-F84 PolarHBondContact O-N 3.43Å; F84-R86 VanDerWaalsContact C-N 3.35Å; F84-R86 PolarHBondContact O-N 3.15Å; F84-R87 WeakPolarHBondContact O-CB 3.41Å; F84-R87 PolarHBondContact O-N 3.12Å; F84-L88 HydrophobicContact CD1-CD1 4.48Å; F84-L88 HydrophobicContact CE1-CD1 3.65Å; F84-L88 HydrophobicContact CE1-CG 4.34Å; F84-L88 HydrophobicContact CZ-CD1 4.11Å; F84-N685 WeakPolarHBondContact CD2-O 3.14Å; F84-D687 HydrophobicContact CD1-CB 3.76Å; F84-D687 HydrophobicContact CD2-CB 4.14Å; F84-D687 HydrophobicContact CE1-CB 3.39Å; F84-D687 WeakPolarHBondContact CE1-OD2 3.29Å; F84-D687 HydrophobicContact CE2-CB 3.79Å; F84-D687 HydrophobicContact CG-CB 4.14Å; F84-D687 HydrophobicContact CZ-CB 3.42Å; F84-D687 VanDerWaalsContact CZ-CB 3.42Å; F84-D687 VanDerWaalsContact CZ-CG 3.41Å; F84-D687 VanDerWaalsContact CZ-OD2 3.27Å; F84-D687 WeakPolarHBondContact CZ-OD2 3.29Å
85Y98.8Very high98.2Very high6 Ų632 Ų322%0.02415%0.154CC..Hα-helixtrans-68.9-29.4-167.3-166.1-116000113.6G81 M82 R87 L88 W95 A393 F397 S707 N710 V711G81-Y85 VanDerWaalsContact O-CB 3.27Å; G81-Y85 WeakPolarHBondContact O-CB 3.32Å; G81-Y85 PolarHBondContact O-N 3.33Å; M82-Y85 PolarHBondContact O-N 3.25Å; Y85-R87 PolarHBondContact O-N 3.37Å; Y85-L88 HydrophobicContact CD2-CD1 4.05Å; Y85-L88 HydrophobicContact CE2-CD1 4.35Å; Y85-L88 WeakPolarHBondContact O-CB 3.41Å; Y85-L88 PolarHBondContact O-N 3.21Å; Y85-W95 AromaticContact CD1-CD1 3.99Å; Y85-W95 AromaticContact CD1-NE1 3.51Å; Y85-W95 AromaticContact CE1-CD1 3.42Å; Y85-W95 VanDerWaalsContact CE1-CD1 3.42Å; Y85-W95 HydrophobicContact CE1-CD2 4.18Å; Y85-W95 AromaticContact CE1-CE2 3.87Å; Y85-W95 AromaticContact CE1-CG 3.91Å; Y85-W95 HydrophobicContact CE1-CG 3.91Å; Y85-W95 AromaticContact CE1-NE1 3.37Å; Y85-W95 AromaticContact CE2-CD1 3.84Å; Y85-W95 AromaticContact CZ-CD1 3.32Å; Y85-W95 AromaticContact CZ-CG 3.88Å; Y85-W95 AromaticContact CZ-NE1 3.75Å; Y85-W95 PolarHBondContact O-NE1 3.21Å; Y85-A393 HydrophobicContact CE1-CB 4Å; Y85-F397 AromaticContact CD1-CE1 3.87Å; Y85-F397 HydrophobicContact CD1-CE1 3.87Å; Y85-F397 HydrophobicContact CD1-CZ 4.09Å; Y85-S707 WeakPolarHBondContact OH-CB 3.15Å; Y85-S707 PolarHBondContact OH-OG 3.09Å; Y85-N710 HydrophobicContact CD1-CB 4.44Å; Y85-N710 HydrophobicContact CD2-CB 3.37Å; Y85-N710 HydrophobicContact CE2-CB 3.64Å; Y85-N710 HydrophobicContact CG-CB 3.83Å; Y85-V711 HydrophobicContact CE1-CG2 3.66Å
86R98.3Very high98.3Very high78 Ų7829 Ų2929%0.29414%0.14SC..G310 helixtrans-59.5-25.6171.670.3173.3-118.2173.114.1113.6M82 N83 F84 L88 Q89 F397 K407 L408 C411M82-R86 WeakPolarHBondContact O-CB 3.35Å; M82-R86 VanDerWaalsContact O-CG 3.28Å; M82-R86 WeakPolarHBondContact O-CG 3.36Å; M82-R86 PolarHBondContact O-N 2.91Å; N83-R86 WeakPolarHBondContact O-CG 3.4Å; F84-R86 VanDerWaalsContact C-N 3.35Å; F84-R86 PolarHBondContact O-N 3.15Å; R86-L88 PolarHBondContact O-N 3.37Å; R86-Q89 WeakPolarHBondContact O-CB 3.3Å; R86-Q89 PolarHBondContact O-N 2.84Å; R86-F397 HydrophobicContact CB-CE2 4.24Å; R86-F397 HydrophobicContact CB-CZ 4.45Å; R86-K407 VanDerWaalsContact NH1-C 3.31Å; R86-K407 PolarHBondContact NH1-O 3.37Å; R86-L408 HydrophobicContact CB-CD2 4.36Å; R86-L408 HydrophobicContact CG-CD2 4.3Å; R86-C411 HydrophobicContact CB-CB 4.45Å
87R97.9Very high98.3Very high123 Ų12326.4 Ų26.446%0.46413%0.126SC..G310 helixtrans-80-10-179.6-61.5175.5174.5-103.15.2112.1M51 F64 F84 Y85M51-R87 HydrophobicContact CE-CB 4.09Å; M51-R87 HydrophobicContact SD-CB 3.39Å; M51-R87 WeakPolarHBondContact SD-CB 3.43Å; M51-R87 VanDerWaalsContact SD-CD 3.57Å; M51-R87 HydrophobicContact SD-CG 4.12Å; F64-R87 PolarHBondContact O-NH1 3.12Å; F84-R87 WeakPolarHBondContact O-CB 3.41Å; F84-R87 PolarHBondContact O-N 3.12Å; Y85-R87 PolarHBondContact O-N 3.37Å
88L98.7Very high98.3Very high7 Ų726.8 Ų26.84%0.03713%0.128CC..G310 helixtrans-95.3-0.4172-55.3-175.6000112.4M51 L52 H55 F84 Y85 R86 A90M51-L88 HydrophobicContact CE-CD2 4.23Å; M51-L88 HydrophobicContact CG-CD2 4.22Å; L52-L88 HydrophobicContact CD1-CB 4.4Å; H55-L88 HydrophobicContact CB-CD2 3.79Å; F84-L88 HydrophobicContact CD1-CD1 4.48Å; F84-L88 HydrophobicContact CE1-CD1 3.65Å; F84-L88 HydrophobicContact CE1-CG 4.34Å; F84-L88 HydrophobicContact CZ-CD1 4.11Å; Y85-L88 HydrophobicContact CD2-CD1 4.05Å; Y85-L88 HydrophobicContact CE2-CD1 4.35Å; Y85-L88 WeakPolarHBondContact O-CB 3.41Å; Y85-L88 PolarHBondContact O-N 3.21Å; R86-L88 PolarHBondContact O-N 3.37Å; L88-A90 PolarHBondContact O-N 3.08Å
89Q98.8Very high98.4Very high30 Ų3027.3 Ų27.314%0.1413%0.13CC..BIsolated β-bridgetrans-64.9131.2171.3-166.8179.926.700109.2R86 G93 W95 C411R86-Q89 WeakPolarHBondContact O-CB 3.3Å; R86-Q89 PolarHBondContact O-N 2.84Å; Q89-G93 PolarHBondContact NE2-O 3.03Å; Q89-W95 HydrophobicContact CB-CD2 4.29Å; Q89-W95 HydrophobicContact CB-CH2 4.35Å; Q89-W95 HydrophobicContact CB-CZ2 3.8Å; Q89-W95 HydrophobicContact CG-CD2 4.18Å; Q89-W95 HydrophobicContact CG-CE3 4.21Å; Q89-W95 HydrophobicContact CG-CH2 3.93Å; Q89-W95 HydrophobicContact CG-CZ2 3.89Å; Q89-W95 HydrophobicContact CG-CZ3 4.07Å; Q89-C411 PolarHBondContact NE2-O 2.75Å; Q89-C411 VanDerWaalsContact OE1-CA 3.27Å; Q89-C411 PolarHBondContact OE1-SG 2.97Å
90A98.5Very high98.4Very high4 Ų425.7 Ų25.73%0.03312%0.116CC..  trans-68.2159.8173.400000111.1N29 L52 L88 D92 G93 H94N29-A90 HydrophobicContact CB-CB 3.94Å; L52-A90 HydrophobicContact CD2-CB 4.24Å; L88-A90 PolarHBondContact O-N 3.08Å; A90-D92 WeakPolarHBondContact CB-OD1 3.17Å; A90-D92 PolarHBondContact O-N 3.23Å; A90-D92 VanDerWaalsContact O-N 3.09Å; A90-G93 PolarHBondContact O-N 3.22Å; A90-H94 WeakPolarHBondContact CB-O 3.45Å; A90-H94 PolarHBondContact N-O 3.37Å
91E97.1Very high98.4Very high120 Ų12024.3 Ų24.356%0.56111%0.111SC*.THydrogen-bonded Turntrans-63.3-16.7-175.764.5-90.6-14900114.8N29N29-E91 HydrophobicContact CB-CG 4.49Å; N29-E91 PolarHBondContact N-OE1 2.85Å; N29-E91 VanDerWaalsContact N-OE1 3.13Å; N29-E91 PolarHBondContact ND2-OE2 3.13Å
92D97.9Very high98.4Very high35 Ų3524.5 Ų24.519%0.18711%0.112CC..THydrogen-bonded Turntrans-103.713176.164.3-6.7000113A30 E31 G32 A90 H94 F418A30-D92 WeakPolarHBondContact CA-OD2 3.41Å; A30-D92 PolarHBondContact N-OD2 3.06Å; E31-D92 PolarHBondContact N-OD2 3.47Å; G32-D92 PolarHBondContact N-OD2 2.83Å; A90-D92 WeakPolarHBondContact CB-OD1 3.17Å; A90-D92 PolarHBondContact O-N 3.23Å; A90-D92 VanDerWaalsContact O-N 3.09Å; D92-H94 IonicContact OD1-CE1 3.42Å; D92-H94 PolarHBondContact OD1-CE1 3.48Å; D92-H94 IonicContact OD1-CG 2.96Å; D92-H94 IonicContact OD1-ND1 3.88Å; D92-H94 PolarHBondContact OD1-ND1 3.42Å; D92-H94 IonicContact OD2-CE1 2.74Å; D92-H94 IonicContact OD2-ND1 3.86Å; D92-F418 WeakPolarHBondContact O-CB 3.48Å
93G98.3Very high98.4Very high0 Ų024.4 Ų24.40%011%0.112CC..SBendtrans94.1-8.1166.800000116.5Q89 A90 A415Q89-G93 PolarHBondContact NE2-O 3.03Å; A90-G93 PolarHBondContact O-N 3.22Å; G93-A415 WeakPolarHBondContact O-CA 3.35Å
94H98.8Very high98.5Very high0 Ų022 Ų220%010%0.099CC..  trans-89.9171.3175.985.2-78000112.4N29 Q34 A90 D92 Q386 T390 F418N29-H94 PolarHBondContact OD1-CE1 3.46Å; Q34-H94 PolarHBondContact NE2-NE2 2.57Å; A90-H94 WeakPolarHBondContact CB-O 3.45Å; A90-H94 PolarHBondContact N-O 3.37Å; D92-H94 IonicContact OD1-CE1 3.42Å; D92-H94 PolarHBondContact OD1-CE1 3.48Å; D92-H94 IonicContact OD1-CG 2.96Å; D92-H94 IonicContact OD1-ND1 3.88Å; D92-H94 PolarHBondContact OD1-ND1 3.42Å; D92-H94 IonicContact OD2-CE1 2.74Å; D92-H94 IonicContact OD2-ND1 3.86Å; H94-Q386 HydrophobicContact CB-CB 4.49Å; H94-Q386 WeakPolarHBondContact CD2-CG 2.99Å; H94-T390 WeakPolarHBondContact CA-OG1 3.07Å; H94-T390 WeakPolarHBondContact CB-OG1 2.97Å; H94-F418 HydrophobicContact CB-CD1 3.64Å; H94-F418 HydrophobicContact CB-CD2 3.71Å; H94-F418 HydrophobicContact CB-CE1 3.59Å; H94-F418 HydrophobicContact CB-CE2 3.69Å; H94-F418 HydrophobicContact CB-CG 3.69Å; H94-F418 HydrophobicContact CB-CZ 3.62Å
95W98.9Very high98.5Very high2 Ų222.4 Ų22.41%0.00810%0.101CC..BIsolated β-bridgetrans-104.7125.9168.9-79.9-99.7000111Y85 Q89 T390 A393 F397 C411 A415Y85-W95 AromaticContact CD1-CD1 3.99Å; Y85-W95 AromaticContact CD1-NE1 3.51Å; Y85-W95 AromaticContact CE1-CD1 3.42Å; Y85-W95 VanDerWaalsContact CE1-CD1 3.42Å; Y85-W95 HydrophobicContact CE1-CD2 4.18Å; Y85-W95 AromaticContact CE1-CE2 3.87Å; Y85-W95 AromaticContact CE1-CG 3.91Å; Y85-W95 HydrophobicContact CE1-CG 3.91Å; Y85-W95 AromaticContact CE1-NE1 3.37Å; Y85-W95 AromaticContact CE2-CD1 3.84Å; Y85-W95 AromaticContact CZ-CD1 3.32Å; Y85-W95 AromaticContact CZ-CG 3.88Å; Y85-W95 AromaticContact CZ-NE1 3.75Å; Y85-W95 PolarHBondContact O-NE1 3.21Å; Q89-W95 HydrophobicContact CB-CD2 4.29Å; Q89-W95 HydrophobicContact CB-CH2 4.35Å; Q89-W95 HydrophobicContact CB-CZ2 3.8Å; Q89-W95 HydrophobicContact CG-CD2 4.18Å; Q89-W95 HydrophobicContact CG-CE3 4.21Å; Q89-W95 HydrophobicContact CG-CH2 3.93Å; Q89-W95 HydrophobicContact CG-CZ2 3.89Å; Q89-W95 HydrophobicContact CG-CZ3 4.07Å; W95-T390 HydrophobicContact CE3-CG2 4.11Å; W95-T390 HydrophobicContact CZ3-CG2 4.08Å; W95-T390 PolarHBondContact N-OG1 2.91Å; W95-A393 HydrophobicContact CD2-CB 4.19Å; W95-A393 HydrophobicContact CE3-CB 3.98Å; W95-A393 HydrophobicContact CH2-CB 4.38Å; W95-A393 HydrophobicContact CZ3-CB 4.09Å; W95-F397 HydrophobicContact CZ2-CE2 4.46Å; W95-F397 HydrophobicContact CZ2-CZ 4.33Å; W95-C411 WeakPolarHBondContact CH2-SG 3.38Å; W95-C411 VanDerWaalsContact CZ2-SG 3.56Å; W95-A415 HydrophobicContact CH2-CB 4.42Å; W95-A415 HydrophobicContact CZ3-CB 3.98Å
96A97.9Very high98.5Very high9 Ų922.4 Ų22.47%0.07410%0.101CC..  trans-92.2155176.500000111.6L27 Q34 L52 W371L27-A96 HydrophobicContact CD2-CB 4.11Å; Q34-A96 HydrophobicContact CG-CB 4.19Å; Q34-A96 VanDerWaalsContact NE2-CA 3.31Å; Q34-A96 VanDerWaalsContact NE2-CB 3.31Å; L52-A96 HydrophobicContact CD1-CB 4.46Å; L52-A96 HydrophobicContact CD2-CB 4.25Å; A96-W371 HydrophobicContact CB-CH2 3.96Å; A96-W371 HydrophobicContact CB-CZ3 4.17Å
97G98.2Very high98.5Very high2 Ų218.7 Ų18.72%0.0219%0.087CC..  trans-171.3160.2-178.600000114.6Y99 Q380G97-Y99 PolarHBondContact O-N 3.45Å; G97-Q380 PolarHBondContact O-NE2 2.97Å
98D98.8Very high98.6Very high8 Ų812.9 Ų12.94%0.0437%0.065CC..  trans-63.7128168.6-172.4-37.4000109.1G100 K378 T706D98-G100 PolarHBondContact OD1-N 2.88Å; D98-K378 WeakPolarHBondContact OD1-CD 3.43Å; D98-K378 IonicContact OD1-NZ 2.99Å; D98-K378 WeakPolarHBondContact OD2-CD 3.49Å; D98-K378 VanDerWaalsContact OD2-CE 3.24Å; D98-K378 WeakPolarHBondContact OD2-CE 3.17Å; D98-K378 IonicContact OD2-NZ 3.75Å; D98-K378 PolarHBondContact OD2-NZ 2.78Å; D98-T706 WeakPolarHBondContact CB-OG1 3.34Å; D98-T706 PolarHBondContact N-OG1 3.4Å; D98-T706 PolarHBondContact O-OG1 3.14Å
99Y98.9Very high98.6Very high15 Ų1512.6 Ų12.66%0.0596%0.064CC..  trans-13233179.1-163.8-114.8000110.3G97 Q380 G381 T382 F445 I703 S704 Y705G97-Y99 PolarHBondContact O-N 3.45Å; Y99-Q380 VanDerWaalsContact C-OE1 3.28Å; Y99-G381 PolarHBondContact O-N 3.02Å; Y99-T382 VanDerWaalsContact CD1-OG1 3.22Å; Y99-T382 WeakPolarHBondContact CD1-OG1 3.2Å; Y99-T382 HydrophobicContact CE1-CG2 4.07Å; Y99-T382 WeakPolarHBondContact CE1-OG1 3.28Å; Y99-F445 HydrophobicContact CD1-CE1 4.39Å; Y99-F445 AromaticContact CE1-CE1 3.65Å; Y99-F445 HydrophobicContact CE1-CE1 3.65Å; Y99-F445 HydrophobicContact CE1-CZ 4.15Å; Y99-F445 HydrophobicContact CE2-CE1 4.07Å; Y99-F445 AromaticContact CE2-CZ 3.77Å; Y99-F445 HydrophobicContact CE2-CZ 3.77Å; Y99-F445 AromaticContact CZ-CE1 3.48Å; Y99-F445 VanDerWaalsContact CZ-CE1 3.48Å; Y99-F445 AromaticContact CZ-CZ 3.47Å; Y99-F445 VanDerWaalsContact CZ-CZ 3.47Å; Y99-F445 WeakPolarHBondContact OH-CE1 3.48Å; Y99-F445 VanDerWaalsContact OH-CZ 3.25Å; Y99-F445 WeakPolarHBondContact OH-CZ 3.48Å; Y99-I703 HydrophobicContact CD1-CD1 3.87Å; Y99-I703 HydrophobicContact CD2-CD1 4.4Å; Y99-I703 HydrophobicContact CD2-CG1 4.28Å; Y99-I703 HydrophobicContact CE1-CD1 3.39Å; Y99-I703 HydrophobicContact CE1-CG1 4.26Å; Y99-I703 HydrophobicContact CE2-CD1 3.95Å; Y99-I703 HydrophobicContact CE2-CG1 3.98Å; Y99-I703 HydrophobicContact CG-CD1 4.34Å; Y99-I703 VanDerWaalsContact CZ-CD1 3.42Å; Y99-S704 WeakPolarHBondContact CD2-O 3.32Å; Y99-Y705 HydrophobicContact CE2-CD1 4Å; Y99-Y705 AromaticContact CE2-CE1 3.72Å; Y99-Y705 HydrophobicContact CE2-CE1 3.72Å; Y99-Y705 HydrophobicContact CE2-CE2 4.48Å; Y99-Y705 HydrophobicContact CE2-CG 4.5Å; Y99-Y705 AromaticContact CE2-CZ 3.97Å; Y99-Y705 PolarHBondContact OH-OH 3.31Å
100G98.6Very high98.6Very high0 Ų011.3 Ų11.30%06%0.058CC..  trans-86.5-166.7172.500000112.5D98 P102 S704D98-G100 PolarHBondContact OD1-N 2.88Å; G100-P102 VanDerWaalsContact C-CD 3.5Å; G100-S704 WeakPolarHBondContact O-CB 3.04Å; G100-S704 PolarHBondContact O-N 2.94Å; G100-S704 PolarHBondContact O-OG 3.03Å
101G98.6Very high98.6Very high1 Ų111.1 Ų11.11%0.016%0.057CC..  trans134.6-54.2-177.500000111.7H145 I146G101-H145 CarbonylContact O-C 3.6Å; G101-H145 WeakPolarHBondContact O-CA 3.32Å; G101-H145 WeakPolarHBondContact O-CB 3.29Å; G101-I146 WeakPolarHBondContact O-CG2 3.46Å; G101-I146 PolarHBondContact O-N 2.91Å
102P98.9Very high98.7Very high5 Ų55.4 Ų5.43%0.0323%0.03CC..BIsolated β-bridgetrans-66.3135.4174.7-21.534000112.4G100 F104 L105 F697 A702 I703G100-P102 VanDerWaalsContact C-CD 3.5Å; P102-F104 HydrophobicContact CB-CD1 4.25Å; P102-F104 HydrophobicContact CB-CE1 3.69Å; P102-F104 HydrophobicContact CB-CZ 3.83Å; P102-L105 HydrophobicContact CB-CD1 3.92Å; P102-L105 HydrophobicContact CB-CG 3.96Å; P102-L105 HydrophobicContact CG-CD1 4.22Å; P102-F697 HydrophobicContact CB-CZ 4.37Å; P102-F697 HydrophobicContact CG-CE1 3.7Å; P102-F697 HydrophobicContact CG-CZ 3.73Å; P102-A702 WeakPolarHBondContact CD-O 3.4Å; P102-I703 HydrophobicContact CG-CD1 4.46Å
103L98.8Very high98.7Very high9 Ų94.1 Ų4.15%0.0472%0.023CC..SBendtrans-101.1-0.1-174-67.5175.7000114.3P107 Y131 V135 W142 L144 I146L103-P107 WeakPolarHBondContact O-CD 3.47Å; L103-P107 WeakPolarHBondContact O-CG 3.48Å; L103-Y131 HydrophobicContact CD2-CE1 4.37Å; L103-Y131 WeakPolarHBondContact CD2-OH 3.44Å; L103-V135 HydrophobicContact CD2-CG2 3.83Å; L103-W142 HydrophobicContact CD1-CB 4.15Å; L103-L144 PolarHBondContact N-O 2.59Å; L103-I146 HydrophobicContact CD2-CG2 4.13Å
104F98.7Very high98.8Very high8 Ų85.6 Ų5.64%0.0353%0.03CC..SBendtrans-97.94.9178.555.4-92000114.1P102 L144 F153 W193 I339 F522 F697P102-F104 HydrophobicContact CB-CD1 4.25Å; P102-F104 HydrophobicContact CB-CE1 3.69Å; P102-F104 HydrophobicContact CB-CZ 3.83Å; F104-L144 HydrophobicContact CD1-CD1 3.49Å; F104-L144 VanDerWaalsContact CD1-CD1 3.49Å; F104-L144 HydrophobicContact CD1-CG 4.28Å; F104-L144 WeakPolarHBondContact CD1-O 3.49Å; F104-L144 HydrophobicContact CE1-CD1 3.54Å; F104-L144 HydrophobicContact CE1-CG 4.05Å; F104-F153 HydrophobicContact CB-CE1 3.66Å; F104-F153 HydrophobicContact CB-CE2 4.44Å; F104-F153 HydrophobicContact CB-CZ 3.6Å; F104-F153 HydrophobicContact CD1-CE1 4.07Å; F104-F153 AromaticContact CG-CE1 3.94Å; F104-F153 HydrophobicContact CG-CE1 3.94Å; F104-F153 HydrophobicContact CG-CZ 4.16Å; F104-W193 HydrophobicContact CD2-CZ3 4.5Å; F104-W193 HydrophobicContact CE2-CZ3 4.2Å; F104-I339 HydrophobicContact CD2-CD1 3.89Å; F104-I339 HydrophobicContact CE2-CD1 3.55Å; F104-F522 HydrophobicContact CE1-CE1 4.19Å; F104-F522 AromaticContact CE1-CZ 3.89Å; F104-F522 HydrophobicContact CE1-CZ 3.89Å; F104-F522 HydrophobicContact CE2-CZ 4.08Å; F104-F522 HydrophobicContact CZ-CE1 4.02Å; F104-F522 AromaticContact CZ-CZ 3.55Å; F104-F522 HydrophobicContact CZ-CZ 3.55Å; F104-F697 HydrophobicContact CZ-CE2 4.29Å; F104-F697 HydrophobicContact CZ-CZ 4.09Å
105L98.9Very high98.7Very high8 Ų86.1 Ų6.14%0.0423%0.033CC..Hα-helixtrans-83.4-60.4-177.8-54.8-178.3000112.2P102 P107 G108 L109 P338 I339 M379P102-L105 HydrophobicContact CB-CD1 3.92Å; P102-L105 HydrophobicContact CB-CG 3.96Å; P102-L105 HydrophobicContact CG-CD1 4.22Å; L105-P107 VanDerWaalsContact C-CD 3.42Å; L105-P107 VanDerWaalsContact C-N 3.32Å; L105-G108 PolarHBondContact O-N 3.49Å; L105-G108 VanDerWaalsContact O-N 3.16Å; L105-L109 PolarHBondContact O-N 2.88Å; L105-P338 HydrophobicContact CD1-CG 3.99Å; L105-P338 HydrophobicContact CD2-CB 4.41Å; L105-P338 HydrophobicContact CD2-CG 3.72Å; L105-P338 HydrophobicContact CG-CG 4.35Å; L105-I339 HydrophobicContact CD2-CD1 3.85Å; L105-I339 HydrophobicContact CD2-CG1 3.69Å; L105-M379 HydrophobicContact CB-CB 3.97Å; L105-M379 HydrophobicContact CB-CG 4.15Å; L105-M379 HydrophobicContact CB-SD 3.89Å
106L98.8Very high98.7Very high6 Ų66.3 Ų6.33%0.0314%0.035CC..Hα-helixtrans-56.9-37.8-179.3-172.869.3000113.2G108 L109 L110 M128 Y131 L132 L370 M379L106-G108 PolarHBondContact O-N 3.39Å; L106-L109 HydrophobicContact CD1-CD2 4.2Å; L106-L109 PolarHBondContact O-N 3.29Å; L106-L110 HydrophobicContact CD1-CD1 4.36Å; L106-L110 HydrophobicContact CD1-CG 4.32Å; L106-L110 HydrophobicContact CD2-CD1 4.22Å; L106-L110 HydrophobicContact CG-CD1 3.81Å; L106-L110 HydrophobicContact CG-CG 4.21Å; L106-L110 WeakPolarHBondContact O-CG 3.32Å; L106-L110 PolarHBondContact O-N 3.21Å; L106-M128 HydrophobicContact CD1-CE 4.22Å; L106-M128 HydrophobicContact CD1-CG 4.27Å; L106-M128 HydrophobicContact CD1-SD 3.97Å; L106-M128 HydrophobicContact CD2-CB 4.27Å; L106-M128 HydrophobicContact CD2-CG 4.29Å; L106-Y131 HydrophobicContact CD2-CD1 4.33Å; L106-L132 HydrophobicContact CD2-CD1 4.2Å; L106-L132 HydrophobicContact CD2-CD2 4.23Å; L106-L132 HydrophobicContact CD2-CG 4.16Å; L106-L370 HydrophobicContact CD1-CD2 4.27Å; L106-M379 HydrophobicContact CB-CB 4.18Å; L106-M379 HydrophobicContact CD1-CB 4.37Å
107P98.9Very high98.8Very high0 Ų012.6 Ų12.60%06%0.061CC..Hα-helixtrans-57.1-44.3175-26.234.1000114.4L103 L105 L109 L110 I111 L157 S161L103-P107 WeakPolarHBondContact O-CD 3.47Å; L103-P107 WeakPolarHBondContact O-CG 3.48Å; L105-P107 VanDerWaalsContact C-CD 3.42Å; L105-P107 VanDerWaalsContact C-N 3.32Å; P107-L109 VanDerWaalsContact C-N 3.33Å; P107-L109 PolarHBondContact O-N 2.91Å; P107-L110 PolarHBondContact O-N 2.91Å; P107-I111 WeakPolarHBondContact O-CB 3.48Å; P107-I111 VanDerWaalsContact O-CG1 3.27Å; P107-I111 WeakPolarHBondContact O-CG1 3.36Å; P107-I111 PolarHBondContact O-N 3.34Å; P107-L157 HydrophobicContact CB-CB 3.7Å; P107-L157 HydrophobicContact CB-CD1 4.2Å; P107-L157 HydrophobicContact CB-CG 4.37Å; P107-L157 HydrophobicContact CG-CB 3.73Å; P107-S161 VanDerWaalsContact CA-OG 3.24Å; P107-S161 WeakPolarHBondContact CA-OG 3.13Å; P107-S161 WeakPolarHBondContact CB-OG 3.45Å; P107-S161 WeakPolarHBondContact CG-OG 3.48Å
108G98.9Very high98.8Very high1 Ų113.1 Ų13.11%0.016%0.063CC..Hα-helixtrans-61.6-42.6177.200000111.9L105 L106 T112 W197 T342L105-G108 PolarHBondContact O-N 3.49Å; L105-G108 VanDerWaalsContact O-N 3.16Å; L106-G108 PolarHBondContact O-N 3.39Å; G108-T112 PolarHBondContact O-N 3.43Å; G108-T112 PolarHBondContact O-OG1 3.34Å; G108-W197 VanDerWaalsContact CA-CZ2 3.49Å; G108-W197 WeakPolarHBondContact O-CZ3 3.28Å; G108-T342 WeakPolarHBondContact O-CG2 3.24Å
109L98.9Very high98.6Very high1 Ų118.3 Ų18.31%0.00510%0.097CC..Hα-helixtrans-60.3-48.6176.2175.763.7000111.5L105 L106 P107 T112 C113 T342 M345 I366 L370 M379L105-L109 PolarHBondContact O-N 2.88Å; L106-L109 HydrophobicContact CD1-CD2 4.2Å; L106-L109 PolarHBondContact O-N 3.29Å; P107-L109 VanDerWaalsContact C-N 3.33Å; P107-L109 PolarHBondContact O-N 2.91Å; L109-T112 PolarHBondContact O-N 3.26Å; L109-C113 WeakPolarHBondContact O-CB 3.4Å; L109-C113 PolarHBondContact O-N 3.48Å; L109-C113 PolarHBondContact O-SG 3.19Å; L109-T342 HydrophobicContact CB-CG2 4.44Å; L109-M345 HydrophobicContact CD1-CE 3.93Å; L109-I366 HydrophobicContact CD1-CD1 4.27Å; L109-I366 HydrophobicContact CD1-CG1 4.17Å; L109-I366 HydrophobicContact CD1-CG2 3.99Å; L109-I366 HydrophobicContact CD2-CG2 4Å; L109-L370 HydrophobicContact CD2-CD1 4.43Å; L109-L370 HydrophobicContact CD2-CD2 3.88Å; L109-L370 HydrophobicContact CD2-CG 4.44Å; L109-M379 HydrophobicContact CB-CE 4.25Å; L109-M379 HydrophobicContact CB-SD 3.88Å; L109-M379 HydrophobicContact CD2-CE 4.29Å; L109-M379 HydrophobicContact CD2-SD 4.14Å
110L98.9Very high98.5Very high3 Ų318.9 Ų18.92%0.01610%0.101CC..Hα-helixtrans-67.3-37.9-177.2-69.4170.9000112.4L106 P107 C113 H114 L120 M128 I164 L165L106-L110 HydrophobicContact CD1-CD1 4.36Å; L106-L110 HydrophobicContact CD1-CG 4.32Å; L106-L110 HydrophobicContact CD2-CD1 4.22Å; L106-L110 HydrophobicContact CG-CD1 3.81Å; L106-L110 HydrophobicContact CG-CG 4.21Å; L106-L110 WeakPolarHBondContact O-CG 3.32Å; L106-L110 PolarHBondContact O-N 3.21Å; P107-L110 PolarHBondContact O-N 2.91Å; L110-C113 PolarHBondContact O-N 2.65Å; L110-H114 VanDerWaalsContact O-CB 3.31Å; L110-H114 WeakPolarHBondContact O-CB 3.45Å; L110-H114 PolarHBondContact O-N 3.09Å; L110-L120 HydrophobicContact CD2-CD1 3.95Å; L110-M128 HydrophobicContact CD2-SD 4.1Å; L110-I164 HydrophobicContact CB-CG2 4.2Å; L110-L165 HydrophobicContact CD1-CD1 3.78Å; L110-L165 HydrophobicContact CD1-CG 4.03Å; L110-L165 HydrophobicContact CD2-CD1 4.48Å; L110-L165 HydrophobicContact CD2-CD2 3.77Å; L110-L165 HydrophobicContact CD2-CG 4.12Å
111I98.9Very high98.4Very high1 Ų121.8 Ų21.81%0.00512%0.12CC..Hα-helixtrans-60.6-49.2172.1-70.9169.4000110.1P107 C113 H114 I115 I164 W197 V200 L201P107-I111 WeakPolarHBondContact O-CB 3.48Å; P107-I111 VanDerWaalsContact O-CG1 3.27Å; P107-I111 WeakPolarHBondContact O-CG1 3.36Å; P107-I111 PolarHBondContact O-N 3.34Å; I111-C113 PolarHBondContact O-N 3.23Å; I111-H114 PolarHBondContact O-N 2.94Å; I111-I115 HydrophobicContact CG2-CD1 3.81Å; I111-I115 WeakPolarHBondContact O-CG1 3.32Å; I111-I115 PolarHBondContact O-N 2.91Å; I111-I164 HydrophobicContact CG1-CD1 3.8Å; I111-W197 HydrophobicContact CB-CE3 4.26Å; I111-W197 HydrophobicContact CD1-CB 3.86Å; I111-W197 HydrophobicContact CD1-CE3 4.35Å; I111-W197 HydrophobicContact CD1-CG 4.45Å; I111-W197 HydrophobicContact CG2-CE3 4.05Å; I111-W197 HydrophobicContact CG2-CZ3 4.43Å; I111-V200 HydrophobicContact CG2-CG1 4.09Å; I111-L201 HydrophobicContact CD1-CD2 4.42Å; I111-L201 HydrophobicContact CG1-CD2 4.2Å; I111-L201 HydrophobicContact CG2-CB 4.05Å; I111-L201 HydrophobicContact CG2-CD1 4.32Å
112T98.9Very high98.3Very high0 Ų026.7 Ų26.70%014%0.143CC..Hα-helixtrans-61.2-43.7176.8-68.50000112G108 L109 H114 I115 A116 T342 M345 L346G108-T112 PolarHBondContact O-N 3.43Å; G108-T112 PolarHBondContact O-OG1 3.34Å; L109-T112 PolarHBondContact O-N 3.26Å; T112-H114 VanDerWaalsContact C-N 3.32Å; T112-H114 PolarHBondContact O-N 3.32Å; T112-I115 PolarHBondContact O-N 2.87Å; T112-A116 VanDerWaalsContact O-CB 3.31Å; T112-A116 WeakPolarHBondContact O-CB 3.45Å; T112-A116 PolarHBondContact O-N 3.21Å; T112-T342 HydrophobicContact CG2-CG2 4.41Å; T112-T342 WeakPolarHBondContact OG1-CG2 3.47Å; T112-M345 HydrophobicContact CG2-CE 3.63Å; T112-M345 HydrophobicContact CG2-CG 4.4Å; T112-L346 HydrophobicContact CG2-CB 3.88Å; T112-L346 HydrophobicContact CG2-CD1 4.23Å
113C98.9Very high98.3Very high8 Ų827 Ų275%0.05415%0.145CC..Hα-helixtrans-61.4-40.4176.8-71.90000112.2L109 L110 I111 K117 I118L109-C113 WeakPolarHBondContact O-CB 3.4Å; L109-C113 PolarHBondContact O-N 3.48Å; L109-C113 PolarHBondContact O-SG 3.19Å; L110-C113 PolarHBondContact O-N 2.65Å; I111-C113 PolarHBondContact O-N 3.23Å; C113-K117 CarbonylContact O-C 3.57Å; C113-K117 WeakPolarHBondContact O-CA 3.27Å; C113-K117 PolarHBondContact O-N 3.12Å; C113-I118 HydrophobicContact CB-CB 4.09Å; C113-I118 PolarHBondContact O-N 3.45Å
114H98.8Very high98.2Very high30 Ų3027.8 Ų27.814%0.13915%0.147CC..Hα-helixtrans-64.6-42.7177173.682.2000112.5L110 I111 T112 K117 I164 D254L110-H114 VanDerWaalsContact O-CB 3.31Å; L110-H114 WeakPolarHBondContact O-CB 3.45Å; L110-H114 PolarHBondContact O-N 3.09Å; I111-H114 PolarHBondContact O-N 2.94Å; T112-H114 VanDerWaalsContact C-N 3.32Å; T112-H114 PolarHBondContact O-N 3.32Å; H114-K117 WeakPolarHBondContact O-CD 3.47Å; H114-K117 WeakPolarHBondContact O-CE 3.34Å; H114-K117 PolarHBondContact O-NZ 3.13Å; H114-I164 HydrophobicContact CB-CD1 4.35Å; H114-I164 HydrophobicContact CB-CG1 4.47Å; H114-I164 HydrophobicContact CB-CG2 3.94Å; H114-D254 IonicContact CE1-OD2 3.1Å; H114-D254 PolarHBondContact CE1-OD2 3.04Å; H114-D254 IonicContact NE2-OD2 2.69Å; H114-D254 PolarHBondContact NE2-OD2 3.4Å
115I98.7Very high98.2Very high11 Ų1130.4 Ų30.46%0.05616%0.159CC..Hα-helixtrans-69.6-52179.3-66.6170.4000110.7I111 T112 K117 V200 A251 L346 W349I111-I115 HydrophobicContact CG2-CD1 3.81Å; I111-I115 WeakPolarHBondContact O-CG1 3.32Å; I111-I115 PolarHBondContact O-N 2.91Å; T112-I115 PolarHBondContact O-N 2.87Å; I115-K117 PolarHBondContact O-N 3.09Å; I115-V200 HydrophobicContact CD1-CG1 3.38Å; I115-V200 WeakPolarHBondContact CD1-O 3.44Å; I115-A251 HydrophobicContact CD1-CB 4.12Å; I115-A251 HydrophobicContact CG1-CB 3.75Å; I115-L346 HydrophobicContact CB-CD1 4.27Å; I115-L346 HydrophobicContact CG2-CD1 3.88Å; I115-W349 HydrophobicContact CG2-CE3 4.26Å; I115-W349 HydrophobicContact CG2-CH2 3.55Å; I115-W349 HydrophobicContact CG2-CZ2 4.27Å; I115-W349 HydrophobicContact CG2-CZ3 3.54Å
116A98.6Very high98.2Very high7 Ų734.8 Ų34.86%0.05818%0.177CC..THydrogen-bonded Turntrans-80.44.2-176.200000113.8T112 I118 W349 F359T112-A116 VanDerWaalsContact O-CB 3.31Å; T112-A116 WeakPolarHBondContact O-CB 3.45Å; T112-A116 PolarHBondContact O-N 3.21Å; A116-I118 HydrophobicContact CB-CD1 4Å; A116-I118 HydrophobicContact CB-CG1 3.91Å; A116-I118 PolarHBondContact O-N 3.31Å; A116-W349 HydrophobicContact CB-CB 4.16Å; A116-W349 HydrophobicContact CB-CD2 3.83Å; A116-W349 HydrophobicContact CB-CG 3.56Å; A116-F359 HydrophobicContact CB-CE2 4.28Å; A116-F359 HydrophobicContact CB-CZ 3.95Å
117K98.3Very high98.2Very high140 Ų14034.5 Ų34.561%0.60918%0.176SC*.THydrogen-bonded Turntrans51.541.3-178.8-51.1-60.7171.3-160.60112.5C113 H114 I115 P119C113-K117 CarbonylContact O-C 3.57Å; C113-K117 WeakPolarHBondContact O-CA 3.27Å; C113-K117 PolarHBondContact O-N 3.12Å; H114-K117 WeakPolarHBondContact O-CD 3.47Å; H114-K117 WeakPolarHBondContact O-CE 3.34Å; H114-K117 PolarHBondContact O-NZ 3.13Å; I115-K117 PolarHBondContact O-N 3.09Å; K117-P119 WeakPolarHBondContact O-CD 3.42Å
118I98.6Very high98.2Very high14 Ų1434.5 Ų34.57%0.07218%0.176CC..  trans-77.1118.5178.9-59169000108.5C113 A116 L120 M345 F359 V363 I366C113-I118 HydrophobicContact CB-CB 4.09Å; C113-I118 PolarHBondContact O-N 3.45Å; A116-I118 HydrophobicContact CB-CD1 4Å; A116-I118 HydrophobicContact CB-CG1 3.91Å; A116-I118 PolarHBondContact O-N 3.31Å; I118-L120 PolarHBondContact O-N 3.37Å; I118-M345 HydrophobicContact CD1-CE 3.85Å; I118-M345 HydrophobicContact CD1-CG 4.5Å; I118-M345 HydrophobicContact CD1-SD 4.01Å; I118-F359 HydrophobicContact CD1-CE2 4.14Å; I118-F359 HydrophobicContact CD1-CZ 3.84Å; I118-F359 HydrophobicContact CG1-CZ 3.78Å; I118-V363 HydrophobicContact CD1-CG2 4.03Å; I118-V363 HydrophobicContact CG1-CG2 4.16Å; I118-V363 HydrophobicContact CG2-CG1 4.01Å; I118-V363 HydrophobicContact CG2-CG2 4.29Å; I118-I366 HydrophobicContact CD1-CD1 4.23Å; I118-I366 HydrophobicContact CG2-CD1 3.95Å
119P95.8Very high98.2Very high116 Ų11635.6 Ų35.675%0.75318%0.182SC*.  trans-72.5131176.129.9-33.1000110.2K117K117-P119 WeakPolarHBondContact O-CD 3.42Å
120L96.1Very high98.2Very high27 Ų2736.2 Ų36.214%0.14119%0.185CC..  trans-104.8139.5168.4-65.2178000109.6L110 I118 K125 M128L110-L120 HydrophobicContact CD2-CD1 3.95Å; I118-L120 PolarHBondContact O-N 3.37Å; L120-K125 HydrophobicContact CB-CD 4.41Å; L120-K125 HydrophobicContact CB-CG 3.95Å; L120-M128 HydrophobicContact CD1-CE 4.21Å; L120-M128 HydrophobicContact CD1-SD 4.14Å
121P96.3Very high98.2Very high61 Ų6136.4 Ų36.440%0.39619%0.185SC..  trans-53.8143.5174.4-25.234.1000112.1A123 W124 K125P121-A123 VanDerWaalsContact C-N 3.35Å; P121-A123 PolarHBondContact O-N 2.87Å; P121-W124 HydrophobicContact CB-CB 4.36Å; P121-W124 HydrophobicContact CB-CD2 4.26Å; P121-W124 HydrophobicContact CB-CG 3.88Å; P121-W124 HydrophobicContact CG-CD2 3.86Å; P121-W124 HydrophobicContact CG-CE3 4.3Å; P121-W124 HydrophobicContact CG-CG 4.03Å; P121-W124 HydrophobicContact CG-CZ2 4.43Å; P121-W124 WeakPolarHBondContact O-CB 3.49Å; P121-W124 PolarHBondContact O-N 3.02Å; P121-K125 PolarHBondContact O-N 3.46Å; P121-K125 VanDerWaalsContact O-N 3.14Å
122E97Very high98.2Very high105 Ų10536.4 Ų36.449%0.49119%0.185SC..Hα-helixtrans-59.9-43.8-174.9-173.556.8-141.700112.6W124 K125 K126E122-W124 PolarHBondContact O-N 3.38Å; E122-K125 PolarHBondContact O-N 2.94Å; E122-K125 WeakPolarHBondContact OE2-CE 3.33Å; E122-K125 IonicContact OE2-NZ 2.64Å; E122-K125 PolarHBondContact OE2-NZ 3.4Å; E122-K126 WeakPolarHBondContact O-CG 3.36Å; E122-K126 PolarHBondContact O-N 2.74Å
123A97.9Very high98.2Very high10 Ų1039.8 Ų39.88%0.08320%0.198CC..Hα-helixtrans-57.2-34.9175.100000112.6T20 W25 Y38 P121 E127T20-A123 HydrophobicContact CG2-CB 4.06Å; W25-A123 HydrophobicContact CH2-CB 4.22Å; W25-A123 HydrophobicContact CZ2-CB 3.85Å; Y38-A123 HydrophobicContact CD1-CB 3.7Å; Y38-A123 HydrophobicContact CD2-CB 4.08Å; Y38-A123 HydrophobicContact CE1-CB 4.35Å; Y38-A123 HydrophobicContact CG-CB 3.53Å; P121-A123 VanDerWaalsContact C-N 3.35Å; P121-A123 PolarHBondContact O-N 2.87Å; A123-E127 WeakPolarHBondContact O-CG 3.34Å; A123-E127 PolarHBondContact O-N 3.31Å; A123-E127 VanDerWaalsContact O-N 3.08Å
124W98.5Very high98.2Very high26 Ų2640.4 Ų40.410%0.09820%0.203CC..Hα-helixtrans-70.7-45.6179.2-65.623.1000110.6W25 W36 P121 E122 K126 E127 M128 P367 L370 M377W25-W124 AromaticContact CH2-CD1 3.29Å; W25-W124 HydrophobicContact CH2-CG 4.2Å; W25-W124 AromaticContact CH2-NE1 3.68Å; W25-W124 AromaticContact CZ3-CD1 3.7Å; W25-W124 AromaticContact CZ3-NE1 3.55Å; W36-W124 WeakPolarHBondContact O-CZ2 3.48Å; P121-W124 HydrophobicContact CB-CB 4.36Å; P121-W124 HydrophobicContact CB-CD2 4.26Å; P121-W124 HydrophobicContact CB-CG 3.88Å; P121-W124 HydrophobicContact CG-CD2 3.86Å; P121-W124 HydrophobicContact CG-CE3 4.3Å; P121-W124 HydrophobicContact CG-CG 4.03Å; P121-W124 HydrophobicContact CG-CZ2 4.43Å; P121-W124 WeakPolarHBondContact O-CB 3.49Å; P121-W124 PolarHBondContact O-N 3.02Å; E122-W124 PolarHBondContact O-N 3.38Å; W124-K126 VanDerWaalsContact C-N 3.31Å; W124-K126 PolarHBondContact O-N 3.44Å; W124-E127 PolarHBondContact O-N 3.37Å; W124-M128 HydrophobicContact CB-CE 4.42Å; W124-M128 WeakPolarHBondContact O-CB 3.47Å; W124-M128 VanDerWaalsContact O-CG 3.25Å; W124-M128 WeakPolarHBondContact O-CG 3.26Å; W124-M128 PolarHBondContact O-N 3.04Å; W124-P367 HydrophobicContact CH2-CB 3.66Å; W124-P367 HydrophobicContact CH2-CG 3.67Å; W124-P367 HydrophobicContact CZ3-CB 4.35Å; W124-P367 HydrophobicContact CZ3-CG 4.21Å; W124-L370 HydrophobicContact CE3-CD1 3.55Å; W124-L370 HydrophobicContact CZ3-CD1 3.55Å; W124-M377 HydrophobicContact CB-CE 4.29Å; W124-M377 HydrophobicContact CB-SD 3.73Å; W124-M377 HydrophobicContact CD2-CE 4.08Å; W124-M377 HydrophobicContact CD2-SD 4.02Å; W124-M377 HydrophobicContact CE3-SD 4.27Å; W124-M377 HydrophobicContact CG-CE 3.87Å; W124-M377 HydrophobicContact CG-SD 3.83Å
125K98.7Very high98.2Very high64 Ų6439.7 Ų39.728%0.27820%0.201SC..Hα-helixtrans-58-44.8175.9-67.1-175.6-68.2165.50111.3L120 P121 E122 E127 M128 V129 L165L120-K125 HydrophobicContact CB-CD 4.41Å; L120-K125 HydrophobicContact CB-CG 3.95Å; P121-K125 PolarHBondContact O-N 3.46Å; P121-K125 VanDerWaalsContact O-N 3.14Å; E122-K125 PolarHBondContact O-N 2.94Å; E122-K125 WeakPolarHBondContact OE2-CE 3.33Å; E122-K125 IonicContact OE2-NZ 2.64Å; E122-K125 PolarHBondContact OE2-NZ 3.4Å; K125-E127 PolarHBondContact O-N 3.1Å; K125-M128 PolarHBondContact O-N 2.84Å; K125-V129 WeakPolarHBondContact O-CG2 3.41Å; K125-V129 PolarHBondContact O-N 2.89Å; K125-L165 HydrophobicContact CB-CD2 3.97Å; K125-L165 HydrophobicContact CD-CD2 4.48Å; K125-L165 HydrophobicContact CG-CD2 3.9Å
126K98.7Very high98.2Very high99 Ų9939.6 Ų39.643%0.4320%0.2SC..Hα-helixtrans-58-48175.9-72.9179178.7179.70112.2A19 T20 E122 W124 V129 R130A19-K126 HydrophobicContact CB-CB 4Å; T20-K126 HydrophobicContact CG2-CB 4.07Å; T20-K126 HydrophobicContact CG2-CD 4.15Å; E122-K126 WeakPolarHBondContact O-CG 3.36Å; E122-K126 PolarHBondContact O-N 2.74Å; W124-K126 VanDerWaalsContact C-N 3.31Å; W124-K126 PolarHBondContact O-N 3.44Å; K126-V129 PolarHBondContact O-N 3.35Å; K126-R130 WeakPolarHBondContact O-CB 3.08Å; K126-R130 PolarHBondContact O-N 3.3Å
127E98.9Very high98.2Very high0 Ų039.6 Ų39.60%020%0.199CC..Hα-helixtrans-73.2-26179.9-69.7-60.7145.100113.3A19 T20 W25 A123 W124 K125 R130 Y131 L372 M377A19-E127 PolarHBondContact N-OE1 3.13Å; T20-E127 WeakPolarHBondContact CB-OE1 3.48Å; T20-E127 HydrophobicContact CG2-CG 4.09Å; T20-E127 PolarHBondContact N-OE1 2.91Å; T20-E127 PolarHBondContact OG1-OE1 3.3Å; W25-E127 HydrophobicContact CZ2-CB 4.45Å; W25-E127 HydrophobicContact CZ2-CG 3.71Å; A123-E127 WeakPolarHBondContact O-CG 3.34Å; A123-E127 PolarHBondContact O-N 3.31Å; A123-E127 VanDerWaalsContact O-N 3.08Å; W124-E127 PolarHBondContact O-N 3.37Å; K125-E127 PolarHBondContact O-N 3.1Å; E127-R130 IonicContact OE1-NH1 2.97Å; E127-R130 WeakPolarHBondContact OE2-CD 3.36Å; E127-R130 IonicContact OE2-CZ 2.98Å; E127-R130 IonicContact OE2-NE 3.74Å; E127-R130 IonicContact OE2-NH1 3.94Å; E127-R130 PolarHBondContact OE2-NH1 2.95Å; E127-Y131 WeakPolarHBondContact O-CB 3.49Å; E127-Y131 PolarHBondContact O-N 3.36Å; E127-L372 HydrophobicContact CB-CD1 3.83Å; E127-L372 HydrophobicContact CG-CD1 3.78Å; E127-M377 HydrophobicContact CB-CB 3.64Å; E127-M377 PolarHBondContact O-N 2.78Å
128M98.9Very high98.2Very high0 Ų036.1 Ų36.10%019%0.19CC..Hα-helixtrans-70.4-43.2170.2-72.2174-173.500111.8L106 L110 L120 W124 K125 R130 Y131 L132 L165 L370 M377L106-M128 HydrophobicContact CD1-CE 4.22Å; L106-M128 HydrophobicContact CD1-CG 4.27Å; L106-M128 HydrophobicContact CD1-SD 3.97Å; L106-M128 HydrophobicContact CD2-CB 4.27Å; L106-M128 HydrophobicContact CD2-CG 4.29Å; L110-M128 HydrophobicContact CD2-SD 4.1Å; L120-M128 HydrophobicContact CD1-CE 4.21Å; L120-M128 HydrophobicContact CD1-SD 4.14Å; W124-M128 HydrophobicContact CB-CE 4.42Å; W124-M128 WeakPolarHBondContact O-CB 3.47Å; W124-M128 VanDerWaalsContact O-CG 3.25Å; W124-M128 WeakPolarHBondContact O-CG 3.26Å; W124-M128 PolarHBondContact O-N 3.04Å; K125-M128 PolarHBondContact O-N 2.84Å; M128-R130 VanDerWaalsContact C-N 3.32Å; M128-Y131 PolarHBondContact O-N 3.47Å; M128-L132 WeakPolarHBondContact O-CG 3.26Å; M128-L132 PolarHBondContact O-N 2.76Å; M128-L165 HydrophobicContact CB-CD1 3.92Å; M128-L370 HydrophobicContact CE-CD1 3.39Å; M128-L370 HydrophobicContact CE-CD2 3.75Å; M128-L370 HydrophobicContact CE-CG 4.2Å; M128-M377 HydrophobicContact CE-CG 4.31Å; M128-M377 HydrophobicContact CE-SD 3.72Å; M128-M377 HydrophobicContact CG-CB 4.13Å; M128-M377 HydrophobicContact CG-CG 4.11Å; M128-M377 HydrophobicContact CG-SD 4.29Å
129V98.9Very high98.2Very high24 Ų2437.5 Ų37.515%0.14520%0.198CC..Hα-helixtrans-58.9-47.4172.4169.70000109.8K125 K126 Y131 L132 R133 L162 L165 V167K125-V129 WeakPolarHBondContact O-CG2 3.41Å; K125-V129 PolarHBondContact O-N 2.89Å; K126-V129 PolarHBondContact O-N 3.35Å; V129-Y131 PolarHBondContact O-N 3.28Å; V129-L132 PolarHBondContact O-N 2.77Å; V129-R133 WeakPolarHBondContact O-CG 3.43Å; V129-R133 PolarHBondContact O-N 2.91Å; V129-L162 HydrophobicContact CB-CD2 4.32Å; V129-L162 HydrophobicContact CG1-CD2 3.98Å; V129-L162 HydrophobicContact CG2-CD2 4.29Å; V129-L165 HydrophobicContact CG2-CB 3.65Å; V129-L165 HydrophobicContact CG2-CD1 3.79Å; V129-L165 HydrophobicContact CG2-CG 4.26Å; V129-V167 HydrophobicContact CG1-CG2 4.03Å; V129-V167 HydrophobicContact CG2-CG2 4.2Å
130R98.9Very high98.3Very high15 Ų1532 Ų326%0.05716%0.162CC..Hα-helixtrans-56.4-49.6175.4-177-156.2169.2-169.7-4.7111.1T16 E17 P18 A19 K126 E127 M128 L132 R133 S134 L374T16-R130 PolarHBondContact O-NH2 2.92Å; T16-R130 PolarHBondContact OG1-NE 3.48Å; T16-R130 VanDerWaalsContact OG1-NE 3.16Å; T16-R130 PolarHBondContact OG1-NH2 3.43Å; E17-R130 WeakPolarHBondContact O-CD 3.49Å; E17-R130 PolarHBondContact O-NE 3.16Å; P18-R130 VanDerWaalsContact CA-CZ 3.41Å; A19-R130 HydrophobicContact CB-CB 4.08Å; K126-R130 WeakPolarHBondContact O-CB 3.08Å; K126-R130 PolarHBondContact O-N 3.3Å; E127-R130 IonicContact OE1-NH1 2.97Å; E127-R130 WeakPolarHBondContact OE2-CD 3.36Å; E127-R130 IonicContact OE2-CZ 2.98Å; E127-R130 IonicContact OE2-NE 3.74Å; E127-R130 IonicContact OE2-NH1 3.94Å; E127-R130 PolarHBondContact OE2-NH1 2.95Å; M128-R130 VanDerWaalsContact C-N 3.32Å; R130-L132 PolarHBondContact O-N 3.41Å; R130-R133 PolarHBondContact O-N 3.42Å; R130-S134 WeakPolarHBondContact O-CB 3.37Å; R130-S134 PolarHBondContact O-N 2.95Å; R130-S134 PolarHBondContact O-OG 2.95Å; R130-L374 PolarHBondContact NH2-O 3.14Å
131Y98.9Very high98.4Very high6 Ų630.7 Ų30.72%0.02416%0.155CC..Hα-helixtrans-55-52178.7171.6-112.2000112.4L103 L106 E127 M128 V129 R133 S134 V135 D375 M377 K378L103-Y131 HydrophobicContact CD2-CE1 4.37Å; L103-Y131 WeakPolarHBondContact CD2-OH 3.44Å; L106-Y131 HydrophobicContact CD2-CD1 4.33Å; E127-Y131 WeakPolarHBondContact O-CB 3.49Å; E127-Y131 PolarHBondContact O-N 3.36Å; M128-Y131 PolarHBondContact O-N 3.47Å; V129-Y131 PolarHBondContact O-N 3.28Å; Y131-R133 VanDerWaalsContact C-N 3.31Å; Y131-R133 PolarHBondContact O-N 3.11Å; Y131-S134 WeakPolarHBondContact O-CB 3.43Å; Y131-S134 PolarHBondContact O-N 3.27Å; Y131-S134 VanDerWaalsContact O-N 3.12Å; Y131-V135 HydrophobicContact CD2-CG1 4.04Å; Y131-V135 HydrophobicContact CE1-CG2 4.36Å; Y131-V135 HydrophobicContact CE2-CG1 3.53Å; Y131-V135 HydrophobicContact CE2-CG2 4.27Å; Y131-V135 WeakPolarHBondContact O-CG2 3.24Å; Y131-V135 PolarHBondContact O-N 3.41Å; Y131-D375 VanDerWaalsContact CA-O 3.25Å; Y131-D375 WeakPolarHBondContact CA-O 3.47Å; Y131-D375 HydrophobicContact CD2-CB 4.49Å; Y131-D375 PolarHBondContact N-O 3.14Å; Y131-M377 VanDerWaalsContact CB-O 3.29Å; Y131-M377 WeakPolarHBondContact CB-O 3.46Å; Y131-K378 HydrophobicContact CD1-CB 3.8Å; Y131-K378 HydrophobicContact CD2-CB 3.92Å; Y131-K378 HydrophobicContact CE1-CB 3.57Å; Y131-K378 HydrophobicContact CE2-CB 3.72Å; Y131-K378 HydrophobicContact CE2-CD 4.07Å; Y131-K378 VanDerWaalsContact CE2-CE 3.5Å; Y131-K378 HydrophobicContact CG-CB 3.96Å
132L98.9Very high98.5Very high2 Ų227.8 Ų27.81%0.0114%0.136CC..Hα-helixtrans-60.4-40.6-178.9-69.1175.1000111.7L106 M128 V129 R130 V135 Q136 W142 L162 L165L106-L132 HydrophobicContact CD2-CD1 4.2Å; L106-L132 HydrophobicContact CD2-CD2 4.23Å; L106-L132 HydrophobicContact CD2-CG 4.16Å; M128-L132 WeakPolarHBondContact O-CG 3.26Å; M128-L132 PolarHBondContact O-N 2.76Å; V129-L132 PolarHBondContact O-N 2.77Å; R130-L132 PolarHBondContact O-N 3.41Å; L132-V135 PolarHBondContact O-N 2.99Å; L132-Q136 PolarHBondContact O-N 3.38Å; L132-Q136 VanDerWaalsContact O-N 3.12Å; L132-W142 WeakPolarHBondContact O-CZ2 3.26Å; L132-W142 PolarHBondContact O-NE1 3.23Å; L132-L162 HydrophobicContact CB-CD1 4.24Å; L132-L162 HydrophobicContact CB-CD2 3.93Å; L132-L162 HydrophobicContact CB-CG 4.07Å; L132-L162 HydrophobicContact CD1-CD2 4.07Å; L132-L162 HydrophobicContact CD1-CG 3.89Å; L132-L165 HydrophobicContact CD1-CD1 4.28Å
133R98.9Very high98.6Very high70 Ų7022.8 Ų22.826%0.26411%0.113SC..Hα-helixtrans-65.7-44.1173.5-68.3-177.1-171-92.36.7112.2V129 R130 Y131 V135 Q136 V167 D171 D173V129-R133 WeakPolarHBondContact O-CG 3.43Å; V129-R133 PolarHBondContact O-N 2.91Å; R130-R133 PolarHBondContact O-N 3.42Å; Y131-R133 VanDerWaalsContact C-N 3.31Å; Y131-R133 PolarHBondContact O-N 3.11Å; R133-V135 PolarHBondContact O-N 3.16Å; R133-Q136 WeakPolarHBondContact O-CB 3.48Å; R133-Q136 PolarHBondContact O-N 3.27Å; R133-Q136 VanDerWaalsContact O-N 3.12Å; R133-V167 VanDerWaalsContact NH2-CG1 3.26Å; R133-D171 IonicContact CZ-OD1 3.6Å; R133-D171 IonicContact CZ-OD2 2.64Å; R133-D171 IonicContact NH1-OD1 2.83Å; R133-D171 PolarHBondContact NH1-OD1 3.31Å; R133-D171 IonicContact NH1-OD2 2.92Å; R133-D171 PolarHBondContact NH1-OD2 2.89Å; R133-D171 IonicContact NH2-OD1 3.68Å; R133-D171 IonicContact NH2-OD2 3.86Å; R133-D171 PolarHBondContact NH2-OD2 3.28Å; R133-D173 IonicContact CZ-OD2 3.58Å; R133-D173 VanDerWaalsContact NH1-CG 3.29Å; R133-D173 IonicContact NH1-OD2 2.84Å; R133-D173 PolarHBondContact NH1-OD2 3.08Å
134S98.8Very high98.7Very high22 Ų2222.9 Ų22.915%0.15411%0.113CC..Hα-helixtrans-58-33.9178.8-64.20000112.6R9 T16 R130 Y131 D375R9-S134 PolarHBondContact NH1-O 3.46Å; T16-S134 WeakPolarHBondContact CB-OG 3.35Å; T16-S134 WeakPolarHBondContact CG2-OG 3.44Å; T16-S134 PolarHBondContact OG1-OG 3.34Å; R130-S134 WeakPolarHBondContact O-CB 3.37Å; R130-S134 PolarHBondContact O-N 2.95Å; R130-S134 PolarHBondContact O-OG 2.95Å; Y131-S134 WeakPolarHBondContact O-CB 3.43Å; Y131-S134 PolarHBondContact O-N 3.27Å; Y131-S134 VanDerWaalsContact O-N 3.12Å; S134-D375 WeakPolarHBondContact CB-O 3.48Å; S134-D375 PolarHBondContact OG-O 3Å
135V98.8Very high98.7Very high15 Ų1521.7 Ų21.79%0.09111%0.108CC..THydrogen-bonded Turntrans-99.92.7-179.8-55.50000113.8L103 Y131 L132 R133 L137 I146L103-V135 HydrophobicContact CD2-CG2 3.83Å; Y131-V135 HydrophobicContact CD2-CG1 4.04Å; Y131-V135 HydrophobicContact CE1-CG2 4.36Å; Y131-V135 HydrophobicContact CE2-CG1 3.53Å; Y131-V135 HydrophobicContact CE2-CG2 4.27Å; Y131-V135 WeakPolarHBondContact O-CG2 3.24Å; Y131-V135 PolarHBondContact O-N 3.41Å; L132-V135 PolarHBondContact O-N 2.99Å; R133-V135 PolarHBondContact O-N 3.16Å; V135-L137 PolarHBondContact O-N 2.86Å; V135-I146 HydrophobicContact CG1-CG2 4.25Å
136Q98.8Very high98.7Very high8 Ų819.5 Ų19.54%0.03710%0.099CC..  trans-63.4132.3171.2-165179.633.200109.9R9 L132 R133 G140 W142 D173R9-Q136 VanDerWaalsContact CZ-O 3.32Å; R9-Q136 PolarHBondContact NH1-O 3.42Å; R9-Q136 PolarHBondContact NH2-O 3.29Å; L132-Q136 PolarHBondContact O-N 3.38Å; L132-Q136 VanDerWaalsContact O-N 3.12Å; R133-Q136 WeakPolarHBondContact O-CB 3.48Å; R133-Q136 PolarHBondContact O-N 3.27Å; R133-Q136 VanDerWaalsContact O-N 3.12Å; Q136-G140 PolarHBondContact NE2-O 3.27Å; Q136-W142 HydrophobicContact CB-CD2 4.48Å; Q136-W142 HydrophobicContact CB-CH2 4.05Å; Q136-W142 HydrophobicContact CB-CZ2 3.4Å; Q136-W142 VanDerWaalsContact CD-CH2 3.49Å; Q136-W142 HydrophobicContact CG-CD2 4.2Å; Q136-W142 HydrophobicContact CG-CE3 4.28Å; Q136-W142 HydrophobicContact CG-CH2 3.54Å; Q136-W142 HydrophobicContact CG-CZ2 3.41Å; Q136-W142 VanDerWaalsContact CG-CZ2 3.41Å; Q136-W142 HydrophobicContact CG-CZ3 3.98Å; Q136-W142 VanDerWaalsContact NE2-CH2 3.28Å; Q136-D173 PolarHBondContact NE2-O 2.98Å
137L98.7Very high98.7Very high8 Ų814.9 Ų14.94%0.0428%0.079CC..  trans-73.5158.6178.4-66.8170.8000111.2R9 V135 D139 G140 G141R9-L137 HydrophobicContact CB-CD2 4.16Å; V135-L137 PolarHBondContact O-N 2.86Å; L137-D139 WeakPolarHBondContact CB-OD1 3.42Å; L137-D139 PolarHBondContact O-N 3.34Å; L137-D139 VanDerWaalsContact O-N 3.1Å; L137-G140 PolarHBondContact O-N 3.29Å; L137-G141 WeakPolarHBondContact CB-O 3.23Å; L137-G141 PolarHBondContact N-O 2.8Å
138P98Very high98.6Very high66 Ų6615.7 Ų15.743%0.4298%0.084SC..THydrogen-bonded Turntrans-56.6-26.7178.5-27.136.6000114.4T5 G140T5-P138 HydrophobicContact CG2-CB 4.33Å; P138-G140 PolarHBondContact O-N 2.98Å
139D97.5Very high98.6Very high43 Ų4320.3 Ų20.323%0.2310%0.103CC..THydrogen-bonded Turntrans-82.33.2177.174.7-9.7000114L137 G141 S150 N180L137-D139 WeakPolarHBondContact CB-OD1 3.42Å; L137-D139 PolarHBondContact O-N 3.34Å; L137-D139 VanDerWaalsContact O-N 3.1Å; D139-G141 PolarHBondContact OD1-N 2.94Å; D139-S150 VanDerWaalsContact OD2-CB 3.31Å; D139-S150 WeakPolarHBondContact OD2-CB 3.36Å; D139-S150 PolarHBondContact OD2-OG 3.39Å; D139-N180 PolarHBondContact O-ND2 2.92Å; D139-N180 PolarHBondContact OD1-ND2 2.98Å; D139-N180 PolarHBondContact OD2-ND2 3.38Å; D139-N180 VanDerWaalsContact OD2-ND2 3.11Å
140G98.3Very high98.6Very high0 Ų019.7 Ų19.70%010%0.1CC..SBendtrans88.4-6.8179.200000115.2Q136 L137 P138 W142 A177Q136-G140 PolarHBondContact NE2-O 3.27Å; L137-G140 PolarHBondContact O-N 3.29Å; P138-G140 PolarHBondContact O-N 2.98Å; G140-W142 WeakPolarHBondContact O-CZ3 3.29Å; G140-A177 WeakPolarHBondContact O-CA 3.42Å; G140-A177 VanDerWaalsContact O-CB 3.3Å; G140-A177 WeakPolarHBondContact O-CB 3.5Å
141G98.6Very high98.6Very high0 Ų019.1 Ų19.10%010%0.099CC..  trans-98.6-176.9-17700000114.9L137 D139 T155L137-G141 WeakPolarHBondContact CB-O 3.23Å; L137-G141 PolarHBondContact N-O 2.8Å; D139-G141 PolarHBondContact OD1-N 2.94Å; G141-T155 WeakPolarHBondContact CA-OG1 3.39Å
142W98.9Very high98.6Very high0 Ų018.9 Ų18.90%010%0.097CC..  trans-136.5153170-67.8-97.8000109L103 L132 Q136 G140 S150 T151 G154 T155 S158 L162 A177L103-W142 HydrophobicContact CD1-CB 4.15Å; L132-W142 WeakPolarHBondContact O-CZ2 3.26Å; L132-W142 PolarHBondContact O-NE1 3.23Å; Q136-W142 HydrophobicContact CB-CD2 4.48Å; Q136-W142 HydrophobicContact CB-CH2 4.05Å; Q136-W142 HydrophobicContact CB-CZ2 3.4Å; Q136-W142 VanDerWaalsContact CD-CH2 3.49Å; Q136-W142 HydrophobicContact CG-CD2 4.2Å; Q136-W142 HydrophobicContact CG-CE3 4.28Å; Q136-W142 HydrophobicContact CG-CH2 3.54Å; Q136-W142 HydrophobicContact CG-CZ2 3.41Å; Q136-W142 VanDerWaalsContact CG-CZ2 3.41Å; Q136-W142 HydrophobicContact CG-CZ3 3.98Å; Q136-W142 VanDerWaalsContact NE2-CH2 3.28Å; G140-W142 WeakPolarHBondContact O-CZ3 3.29Å; W142-S150 WeakPolarHBondContact O-CA 3.39Å; W142-T151 PolarHBondContact O-N 2.96Å; W142-G154 CarbonylContact O-C 3.51Å; W142-G154 WeakPolarHBondContact O-CA 3.13Å; W142-T155 HydrophobicContact CE3-CG2 4.41Å; W142-T155 PolarHBondContact N-OG1 3.03Å; W142-T155 PolarHBondContact O-N 3.3Å; W142-T155 PolarHBondContact O-OG1 2.79Å; W142-T155 VanDerWaalsContact O-OG1 3.11Å; W142-S158 VanDerWaalsContact CD2-CB 3.47Å; W142-L162 HydrophobicContact CH2-CD1 3.78Å; W142-L162 HydrophobicContact CZ2-CD1 4.01Å; W142-A177 HydrophobicContact CH2-CB 4.34Å; W142-A177 HydrophobicContact CZ3-CB 3.66Å
143G98.6Very high98.6Very high1 Ų118.8 Ų18.81%0.0110%0.097CC..  trans-108-158.3175.500000113.7H145 K149 G154G143-H145 VanDerWaalsContact C-N 3.34Å; G143-K149 WeakPolarHBondContact CA-O 3.43Å; G143-K149 PolarHBondContact N-O 3.02Å; G143-G154 WeakPolarHBondContact O-CA 3.3Å
144L98.8Very high98.6Very high12 Ų1215.6 Ų15.66%0.0639%0.086CC..SBendtrans-68.3-34.9178-175.667.1000112.2L103 F104 D148 F153 V521 F522 S700 C701L103-L144 PolarHBondContact N-O 2.59Å; F104-L144 HydrophobicContact CD1-CD1 3.49Å; F104-L144 VanDerWaalsContact CD1-CD1 3.49Å; F104-L144 HydrophobicContact CD1-CG 4.28Å; F104-L144 WeakPolarHBondContact CD1-O 3.49Å; F104-L144 HydrophobicContact CE1-CD1 3.54Å; F104-L144 HydrophobicContact CE1-CG 4.05Å; L144-D148 WeakPolarHBondContact CB-OD2 3.49Å; L144-D148 PolarHBondContact N-OD2 3.42Å; L144-F153 HydrophobicContact CD1-CD1 3.73Å; L144-F153 HydrophobicContact CD1-CE1 3.76Å; L144-V521 HydrophobicContact CD1-CB 4.32Å; L144-V521 HydrophobicContact CD1-CG2 4.12Å; L144-V521 HydrophobicContact CD2-CB 4.41Å; L144-F522 HydrophobicContact CD1-CE1 4.22Å; L144-F522 HydrophobicContact CD1-CZ 4.29Å; L144-F522 HydrophobicContact CD2-CE1 4.11Å; L144-S700 WeakPolarHBondContact CD2-O 3.28Å; L144-C701 HydrophobicContact CD2-CB 4.17Å
145H98.8Very high98.6Very high1 Ų114.6 Ų14.61%0.0058%0.079CC..BIsolated β-bridgetrans-146.7173.4-179.358.888000111.5G101 G143 E147 D148 F634 S700 A702G101-H145 CarbonylContact O-C 3.6Å; G101-H145 WeakPolarHBondContact O-CA 3.32Å; G101-H145 WeakPolarHBondContact O-CB 3.29Å; G143-H145 VanDerWaalsContact C-N 3.34Å; H145-E147 VanDerWaalsContact C-N 3.29Å; H145-E147 PolarHBondContact ND1-N 2.76Å; H145-E147 PolarHBondContact O-N 3.04Å; H145-D148 VanDerWaalsContact O-CB 3.23Å; H145-D148 WeakPolarHBondContact O-CB 3.36Å; H145-D148 PolarHBondContact O-N 3.44Å; H145-F634 AromaticContact CE1-CD1 3.63Å; H145-F634 AromaticContact CE1-CE1 3.54Å; H145-F634 AromaticContact NE2-CD1 3.81Å; H145-F634 AromaticContact NE2-CE1 3.27Å; H145-F634 VanDerWaalsContact NE2-CE1 3.27Å; H145-F634 WeakPolarHBondContact NE2-CE1 3.48Å; H145-F634 AromaticContact NE2-CZ 3.83Å; H145-S700 PolarHBondContact CD2-O 2.88Å; H145-S700 PolarHBondContact NE2-O 3.29Å; H145-A702 HydrophobicContact CB-CB 4.13Å; H145-A702 VanDerWaalsContact ND1-CB 3.3Å; H145-A702 WeakPolarHBondContact ND1-CB 3.4Å
146I98.6Very high98.6Very high18 Ų1813.9 Ų13.99%0.0927%0.074CC..THydrogen-bonded Turntrans-63-25.6-172.160.9171.2000115.7R9 G101 L103 V135 I693R9-I146 VanDerWaalsContact O-O 3.08Å; G101-I146 WeakPolarHBondContact O-CG2 3.46Å; G101-I146 PolarHBondContact O-N 2.91Å; L103-I146 HydrophobicContact CD2-CG2 4.13Å; V135-I146 HydrophobicContact CG1-CG2 4.25Å; I146-I693 HydrophobicContact CD1-CD1 3.96Å; I146-I693 HydrophobicContact CG1-CD1 3.94Å
147E98.5Very high98.6Very high1 Ų113.5 Ų13.51%0.0057%0.073CC..THydrogen-bonded Turntrans-93.74.7174.4-61.8-149.4171.100113.1R8 R10 G11 H145 N692 I693R8-E147 WeakPolarHBondContact CD-O 3.25Å; R8-E147 PolarHBondContact NH1-O 2.96Å; R10-E147 IonicContact NH1-OE2 3.83Å; R10-E147 PolarHBondContact NH1-OE2 3.06Å; G11-E147 PolarHBondContact N-OE1 3.44Å; H145-E147 VanDerWaalsContact C-N 3.29Å; H145-E147 PolarHBondContact ND1-N 2.76Å; H145-E147 PolarHBondContact O-N 3.04Å; E147-N692 WeakPolarHBondContact OE1-CA 3.49Å; E147-I693 HydrophobicContact CB-CG2 4.49Å; E147-I693 HydrophobicContact CG-CB 4.18Å; E147-I693 HydrophobicContact CG-CG2 3.75Å; E147-I693 PolarHBondContact OE1-N 2.91Å
148D98.5Very high98.6Very high18 Ų1813.1 Ų13.110%0.0967%0.071CC..SBendtrans-79.4164.6-177.4-159.414.3000112.8R8 L144 H145R8-D148 IonicContact CZ-OD1 3.47Å; R8-D148 VanDerWaalsContact NH1-C 3.29Å; R8-D148 IonicContact NH1-OD1 3.95Å; R8-D148 PolarHBondContact NH1-OD1 3.26Å; L144-D148 WeakPolarHBondContact CB-OD2 3.49Å; L144-D148 PolarHBondContact N-OD2 3.42Å; H145-D148 VanDerWaalsContact O-CB 3.23Å; H145-D148 WeakPolarHBondContact O-CB 3.36Å; H145-D148 PolarHBondContact O-N 3.44Å
149K98.5Very high98.7Very high96 Ų9610 Ų1042%0.4175%0.05SC..PPolyproline II helixtrans-79.1167.4164.7-68.7175.1-175.8171.10109.1L7 R8 G143 T151L7-K149 HydrophobicContact CB-CG 4.32Å; R8-K149 HydrophobicContact CG-CG 3.56Å; G143-K149 WeakPolarHBondContact CA-O 3.43Å; G143-K149 PolarHBondContact N-O 3.02Å; K149-T151 PolarHBondContact O-N 2.81Å
150S98.5Very high98.7Very high11 Ų118 Ų88%0.0774%0.04CC..PPolyproline II helixtrans-65.8133.6174.663.10000111.5D139 W142 K184D139-S150 VanDerWaalsContact OD2-CB 3.31Å; D139-S150 WeakPolarHBondContact OD2-CB 3.36Å; D139-S150 PolarHBondContact OD2-OG 3.39Å; W142-S150 WeakPolarHBondContact O-CA 3.39Å; S150-K184 WeakPolarHBondContact O-CE 3.37Å; S150-K184 WeakPolarHBondContact OG-CE 3.46Å; S150-K184 PolarHBondContact OG-NZ 3.12Å
151T98.9Very high98.8Very high4 Ų48 Ų83%0.0254%0.04CC..  trans-128.2171.917780.90000111.4W142 K149 F153 G154 T155 D285W142-T151 PolarHBondContact O-N 2.96Å; K149-T151 PolarHBondContact O-N 2.81Å; T151-F153 PolarHBondContact OG1-N 3.39Å; T151-G154 PolarHBondContact OG1-N 3.12Å; T151-T155 WeakPolarHBondContact O-CB 3.31Å; T151-T155 PolarHBondContact O-N 3.46Å; T151-T155 PolarHBondContact O-OG1 3.31Å; T151-D285 WeakPolarHBondContact CB-OD1 3.2Å; T151-D285 PolarHBondContact OG1-OD1 3.26Å
152V98.9Very high98.8Very high0 Ų08 Ų80%04%0.04CC..Hα-helixtrans-69.5-39.8174.6178.30000109.7A156 L181 K184 I190 A282 D285V152-A156 WeakPolarHBondContact O-CB 3.33Å; V152-A156 PolarHBondContact O-N 3.46Å; V152-L181 HydrophobicContact CG1-CD1 3.86Å; V152-K184 HydrophobicContact CG2-CB 3.64Å; V152-K184 HydrophobicContact CG2-CD 4.13Å; V152-I190 HydrophobicContact CG1-CB 3.91Å; V152-I190 HydrophobicContact CG1-CG1 4.2Å; V152-A282 HydrophobicContact CB-CB 4.19Å; V152-A282 HydrophobicContact CG2-CB 3.53Å; V152-D285 VanDerWaalsContact CB-OD2 3.31Å; V152-D285 WeakPolarHBondContact CB-OD2 3.2Å; V152-D285 PolarHBondContact N-OD2 2.98Å
153F98.9Very high98.8Very high1 Ų19.3 Ų9.30%0.0045%0.045CC..Hα-helixtrans-60.8-56.2-179.1-169.3-147.6000112.8F104 L144 T151 L157 I190 P191 W193 G194 D285 V521F104-F153 HydrophobicContact CB-CE1 3.66Å; F104-F153 HydrophobicContact CB-CE2 4.44Å; F104-F153 HydrophobicContact CB-CZ 3.6Å; F104-F153 HydrophobicContact CD1-CE1 4.07Å; F104-F153 AromaticContact CG-CE1 3.94Å; F104-F153 HydrophobicContact CG-CE1 3.94Å; F104-F153 HydrophobicContact CG-CZ 4.16Å; L144-F153 HydrophobicContact CD1-CD1 3.73Å; L144-F153 HydrophobicContact CD1-CE1 3.76Å; T151-F153 PolarHBondContact OG1-N 3.39Å; F153-L157 HydrophobicContact CD2-CD1 3.69Å; F153-L157 HydrophobicContact CD2-CG 4.22Å; F153-L157 HydrophobicContact CE2-CD1 3.3Å; F153-L157 HydrophobicContact CE2-CG 4.27Å; F153-L157 HydrophobicContact CZ-CD1 4.08Å; F153-L157 WeakPolarHBondContact O-CB 3.49Å; F153-L157 WeakPolarHBondContact O-CG 3.25Å; F153-L157 PolarHBondContact O-N 3.3Å; F153-I190 HydrophobicContact CD2-CD1 4.28Å; F153-I190 HydrophobicContact CD2-CG1 4.11Å; F153-P191 HydrophobicContact CB-CG 3.9Å; F153-P191 HydrophobicContact CG-CG 4.2Å; F153-W193 HydrophobicContact CE2-CB 4.21Å; F153-W193 HydrophobicContact CZ-CB 3.91Å; F153-G194 VanDerWaalsContact CE2-N 3.35Å; F153-D285 WeakPolarHBondContact CB-OD1 3.2Å; F153-D285 PolarHBondContact N-OD1 3.45Å; F153-D285 VanDerWaalsContact N-OD1 3.16Å; F153-V521 HydrophobicContact CD1-CG1 4.38Å; F153-V521 HydrophobicContact CE1-CG2 4.49Å
154G98.8Very high98.8Very high3 Ų310.8 Ų10.83%0.0315%0.052CC..Hα-helixtrans-62.1-49.6179.400000111.3W142 G143 T151 L157 S158W142-G154 CarbonylContact O-C 3.51Å; W142-G154 WeakPolarHBondContact O-CA 3.13Å; G143-G154 WeakPolarHBondContact O-CA 3.3Å; T151-G154 PolarHBondContact OG1-N 3.12Å; G154-L157 PolarHBondContact O-N 3.31Å; G154-S158 VanDerWaalsContact O-CB 3.28Å; G154-S158 WeakPolarHBondContact O-CB 3.23Å; G154-S158 PolarHBondContact O-N 2.78Å; G154-S158 PolarHBondContact O-OG 2.8Å; G154-S158 VanDerWaalsContact O-OG 3.1Å
155T98.9Very high98.8Very high0 Ų011.4 Ų11.40%06%0.055CC..Hα-helixtrans-65.7-46.3-173.6-52.30000112.9G141 W142 T151 L157 Y159 A177 L181G141-T155 WeakPolarHBondContact CA-OG1 3.39Å; W142-T155 HydrophobicContact CE3-CG2 4.41Å; W142-T155 PolarHBondContact N-OG1 3.03Å; W142-T155 PolarHBondContact O-N 3.3Å; W142-T155 PolarHBondContact O-OG1 2.79Å; W142-T155 VanDerWaalsContact O-OG1 3.11Å; T151-T155 WeakPolarHBondContact O-CB 3.31Å; T151-T155 PolarHBondContact O-N 3.46Å; T151-T155 PolarHBondContact O-OG1 3.31Å; T155-L157 PolarHBondContact O-N 3.47Å; T155-Y159 WeakPolarHBondContact O-CB 3.49Å; T155-Y159 PolarHBondContact O-N 2.98Å; T155-A177 HydrophobicContact CG2-CB 4.35Å; T155-A177 WeakPolarHBondContact CG2-O 3.48Å; T155-L181 HydrophobicContact CG2-CB 3.98Å
156A98.9Very high98.8Very high0 Ų014.4 Ų14.40%09%0.087CC..Hα-helixtrans-64.1-43-179.600000111.5V152 T160 L181 A187 I190V152-A156 WeakPolarHBondContact O-CB 3.33Å; V152-A156 PolarHBondContact O-N 3.46Å; A156-T160 WeakPolarHBondContact O-CB 3.44Å; A156-T160 PolarHBondContact O-N 3.45Å; A156-T160 PolarHBondContact O-OG1 2.97Å; A156-L181 HydrophobicContact CB-CD1 4.01Å; A156-L181 HydrophobicContact CB-CD2 4.12Å; A156-A187 HydrophobicContact CB-CB 4.42Å; A156-I190 HydrophobicContact CB-CD1 3.85Å
157L98.9Very high98.8Very high0 Ų014.2 Ų14.20%09%0.086CC..Hα-helixtrans-73.6-40.6-177.9-70.6-168.6000113.2P107 F153 G154 T155 T160 S161 I190 W197 L198P107-L157 HydrophobicContact CB-CB 3.7Å; P107-L157 HydrophobicContact CB-CD1 4.2Å; P107-L157 HydrophobicContact CB-CG 4.37Å; P107-L157 HydrophobicContact CG-CB 3.73Å; F153-L157 HydrophobicContact CD2-CD1 3.69Å; F153-L157 HydrophobicContact CD2-CG 4.22Å; F153-L157 HydrophobicContact CE2-CD1 3.3Å; F153-L157 HydrophobicContact CE2-CG 4.27Å; F153-L157 HydrophobicContact CZ-CD1 4.08Å; F153-L157 WeakPolarHBondContact O-CB 3.49Å; F153-L157 WeakPolarHBondContact O-CG 3.25Å; F153-L157 PolarHBondContact O-N 3.3Å; G154-L157 PolarHBondContact O-N 3.31Å; T155-L157 PolarHBondContact O-N 3.47Å; L157-T160 PolarHBondContact O-N 3.25Å; L157-S161 WeakPolarHBondContact O-CB 3.34Å; L157-S161 PolarHBondContact O-N 3.43Å; L157-S161 PolarHBondContact O-OG 2.78Å; L157-I190 HydrophobicContact CD2-CD1 4.38Å; L157-I190 HydrophobicContact CG-CD1 4.34Å; L157-W197 HydrophobicContact CD2-CB 4.22Å; L157-L198 HydrophobicContact CD2-CD2 4.03Å; L157-L198 HydrophobicContact CD2-CG 4.34Å
158S98.9Very high98.8Very high0 Ų018.6 Ų18.60%011%0.109CC..Hα-helixtrans-68.6-38.1174.8-62.70000112.1W142 G154 S161 L162W142-S158 VanDerWaalsContact CD2-CB 3.47Å; G154-S158 VanDerWaalsContact O-CB 3.28Å; G154-S158 WeakPolarHBondContact O-CB 3.23Å; G154-S158 PolarHBondContact O-N 2.78Å; G154-S158 PolarHBondContact O-OG 2.8Å; G154-S158 VanDerWaalsContact O-OG 3.1Å; S158-S161 WeakPolarHBondContact O-CB 3.25Å; S158-S161 PolarHBondContact O-N 3.47Å; S158-L162 PolarHBondContact O-N 2.97Å
159Y98.9Very high98.8Very high1 Ų118.8 Ų18.80%0.00411%0.112CC..Hα-helixtrans-57.3-51.6170.6179-85.4000110.7T155 S161 L162 R163 L174 A177 R178 L260 E263 L264T155-Y159 WeakPolarHBondContact O-CB 3.49Å; T155-Y159 PolarHBondContact O-N 2.98Å; Y159-S161 VanDerWaalsContact C-N 3.27Å; Y159-S161 PolarHBondContact O-N 2.72Å; Y159-L162 PolarHBondContact O-N 3.32Å; Y159-R163 HydrophobicContact CD1-CG 3.93Å; Y159-R163 HydrophobicContact CE1-CG 3.58Å; Y159-R163 WeakPolarHBondContact O-CG 3.34Å; Y159-R163 PolarHBondContact O-N 2.93Å; Y159-L174 HydrophobicContact CD2-CB 4.25Å; Y159-L174 HydrophobicContact CD2-CD2 3.87Å; Y159-L174 HydrophobicContact CD2-CG 4.48Å; Y159-L174 HydrophobicContact CE2-CB 3.78Å; Y159-L174 HydrophobicContact CE2-CD1 4.3Å; Y159-L174 HydrophobicContact CE2-CD2 4.21Å; Y159-L174 HydrophobicContact CE2-CG 4.33Å; Y159-L174 WeakPolarHBondContact CE2-O 3.14Å; Y159-A177 HydrophobicContact CD2-CB 3.93Å; Y159-R178 HydrophobicContact CE2-CB 3.88Å; Y159-R178 PolarHBondContact OH-NH1 3.06Å; Y159-L260 HydrophobicContact CD1-CD2 4.34Å; Y159-L260 HydrophobicContact CE1-CD2 4.01Å; Y159-E263 HydrophobicContact CE1-CB 4.08Å; Y159-E263 WeakPolarHBondContact CE1-OE2 3.12Å; Y159-E263 VanDerWaalsContact CZ-OE2 3.24Å; Y159-E263 PolarHBondContact OH-OE2 2.9Å; Y159-L264 HydrophobicContact CD1-CD2 3.69Å; Y159-L264 HydrophobicContact CE1-CD2 4.14Å
160T98.9Very high98.8Very high1 Ų120 Ų201%0.00612%0.123CC..Hα-helixtrans-58.8-40.7179.4-60.50000111.5A156 L157 R163 I164 L201 L260A156-T160 WeakPolarHBondContact O-CB 3.44Å; A156-T160 PolarHBondContact O-N 3.45Å; A156-T160 PolarHBondContact O-OG1 2.97Å; L157-T160 PolarHBondContact O-N 3.25Å; T160-R163 PolarHBondContact O-N 3.42Å; T160-I164 HydrophobicContact CG2-CD1 4.04Å; T160-I164 WeakPolarHBondContact O-CG1 3.49Å; T160-I164 PolarHBondContact O-N 2.93Å; T160-L201 HydrophobicContact CG2-CD2 3.36Å; T160-L260 HydrophobicContact CG2-CD1 4.12Å
161S98.9Very high98.8Very high0 Ų021.1 Ų21.10%013%0.128CC..Hα-helixtrans-60.5-46.5177.1-62.10000112.5P107 L157 S158 Y159 R163 I164 L165P107-S161 VanDerWaalsContact CA-OG 3.24Å; P107-S161 WeakPolarHBondContact CA-OG 3.13Å; P107-S161 WeakPolarHBondContact CB-OG 3.45Å; P107-S161 WeakPolarHBondContact CG-OG 3.48Å; L157-S161 WeakPolarHBondContact O-CB 3.34Å; L157-S161 PolarHBondContact O-N 3.43Å; L157-S161 PolarHBondContact O-OG 2.78Å; S158-S161 WeakPolarHBondContact O-CB 3.25Å; S158-S161 PolarHBondContact O-N 3.47Å; Y159-S161 VanDerWaalsContact C-N 3.27Å; Y159-S161 PolarHBondContact O-N 2.72Å; S161-R163 VanDerWaalsContact C-N 3.33Å; S161-R163 PolarHBondContact O-N 3.5Å; S161-I164 PolarHBondContact O-N 3.35Å; S161-L165 WeakPolarHBondContact O-CG 3.28Å; S161-L165 PolarHBondContact O-N 3.25Å
162L98.9Very high98.8Very high0 Ų025.3 Ų25.30%016%0.155CC..Hα-helixtrans-64.7-37.8177.3-76.4167000111.9V129 L132 W142 S158 Y159 L165 G166 V167 L174V129-L162 HydrophobicContact CB-CD2 4.32Å; V129-L162 HydrophobicContact CG1-CD2 3.98Å; V129-L162 HydrophobicContact CG2-CD2 4.29Å; L132-L162 HydrophobicContact CB-CD1 4.24Å; L132-L162 HydrophobicContact CB-CD2 3.93Å; L132-L162 HydrophobicContact CB-CG 4.07Å; L132-L162 HydrophobicContact CD1-CD2 4.07Å; L132-L162 HydrophobicContact CD1-CG 3.89Å; W142-L162 HydrophobicContact CH2-CD1 3.78Å; W142-L162 HydrophobicContact CZ2-CD1 4.01Å; S158-L162 PolarHBondContact O-N 2.97Å; Y159-L162 PolarHBondContact O-N 3.32Å; L162-L165 CarbonylContact O-C 3.58Å; L162-L165 PolarHBondContact O-N 3Å; L162-G166 PolarHBondContact O-N 2.88Å; L162-V167 HydrophobicContact CB-CB 4.28Å; L162-V167 HydrophobicContact CB-CG2 4.29Å; L162-V167 HydrophobicContact CD2-CG2 4.05Å; L162-V167 WeakPolarHBondContact O-CB 3.38Å; L162-V167 PolarHBondContact O-N 3.4Å; L162-L174 HydrophobicContact CB-CD1 4.27Å; L162-L174 HydrophobicContact CB-CD2 3.83Å; L162-L174 HydrophobicContact CD1-CD2 3.53Å; L162-L174 HydrophobicContact CG-CD2 4.32Å
163R98.9Very high98.8Very high27 Ų2726.8 Ų26.810%0.10216%0.163CC..Hα-helixtrans-64.8-43.1174.7-61.9-69.1-66.7114.1-0.8112Y159 T160 S161 L165 G166 V167 P169 L174 L256 L260 E263Y159-R163 HydrophobicContact CD1-CG 3.93Å; Y159-R163 HydrophobicContact CE1-CG 3.58Å; Y159-R163 WeakPolarHBondContact O-CG 3.34Å; Y159-R163 PolarHBondContact O-N 2.93Å; T160-R163 PolarHBondContact O-N 3.42Å; S161-R163 VanDerWaalsContact C-N 3.33Å; S161-R163 PolarHBondContact O-N 3.5Å; R163-L165 VanDerWaalsContact C-N 3.28Å; R163-L165 PolarHBondContact O-N 3.34Å; R163-G166 PolarHBondContact O-N 3.15Å; R163-V167 WeakPolarHBondContact CD-O 3.47Å; R163-V167 PolarHBondContact NH1-O 2.86Å; R163-P169 VanDerWaalsContact CZ-CD 3.41Å; R163-L174 HydrophobicContact CG-CD1 3.95Å; R163-L256 HydrophobicContact CB-CD1 3.9Å; R163-L260 HydrophobicContact CB-CD2 4Å; R163-L260 HydrophobicContact CG-CD2 3.92Å; R163-E263 IonicContact CZ-OE1 2.98Å; R163-E263 IonicContact CZ-OE2 3.29Å; R163-E263 IonicContact NE-OE1 3.3Å; R163-E263 PolarHBondContact NE-OE1 3.28Å; R163-E263 IonicContact NE-OE2 3.03Å; R163-E263 PolarHBondContact NE-OE2 2.78Å; R163-E263 IonicContact NH2-OE1 2.93Å; R163-E263 PolarHBondContact NH2-OE1 2.83Å; R163-E263 VanDerWaalsContact NH2-OE1 3.09Å; R163-E263 IonicContact NH2-OE2 2.7Å
164I98.9Very high98.8Very high32 Ų3226.8 Ų26.816%0.16416%0.163CC..Hα-helixtrans-60.5-38173.4-72.4169.1000111.5L110 I111 H114 T160 S161 G166 L201 L256L110-I164 HydrophobicContact CB-CG2 4.2Å; I111-I164 HydrophobicContact CG1-CD1 3.8Å; H114-I164 HydrophobicContact CB-CD1 4.35Å; H114-I164 HydrophobicContact CB-CG1 4.47Å; H114-I164 HydrophobicContact CB-CG2 3.94Å; T160-I164 HydrophobicContact CG2-CD1 4.04Å; T160-I164 WeakPolarHBondContact O-CG1 3.49Å; T160-I164 PolarHBondContact O-N 2.93Å; S161-I164 PolarHBondContact O-N 3.35Å; I164-G166 PolarHBondContact O-N 3.23Å; I164-L201 HydrophobicContact CD1-CD1 4.46Å; I164-L201 HydrophobicContact CD1-CD2 4.36Å; I164-L256 HydrophobicContact CB-CD2 4.49Å; I164-L256 HydrophobicContact CG1-CD2 3.92Å
165L98.8Very high98.8Very high26 Ų2628.8 Ų28.814%0.13618%0.175CC..THydrogen-bonded Turntrans-74.3-1.5176.4-71167.7000113.7L110 K125 M128 V129 L132 S161 L162 R163L110-L165 HydrophobicContact CD1-CD1 3.78Å; L110-L165 HydrophobicContact CD1-CG 4.03Å; L110-L165 HydrophobicContact CD2-CD1 4.48Å; L110-L165 HydrophobicContact CD2-CD2 3.77Å; L110-L165 HydrophobicContact CD2-CG 4.12Å; K125-L165 HydrophobicContact CB-CD2 3.97Å; K125-L165 HydrophobicContact CD-CD2 4.48Å; K125-L165 HydrophobicContact CG-CD2 3.9Å; M128-L165 HydrophobicContact CB-CD1 3.92Å; V129-L165 HydrophobicContact CG2-CB 3.65Å; V129-L165 HydrophobicContact CG2-CD1 3.79Å; V129-L165 HydrophobicContact CG2-CG 4.26Å; L132-L165 HydrophobicContact CD1-CD1 4.28Å; S161-L165 WeakPolarHBondContact O-CG 3.28Å; S161-L165 PolarHBondContact O-N 3.25Å; L162-L165 CarbonylContact O-C 3.58Å; L162-L165 PolarHBondContact O-N 3Å; R163-L165 VanDerWaalsContact C-N 3.28Å; R163-L165 PolarHBondContact O-N 3.34Å
166G98.3Very high98.8Very high64 Ų6433.5 Ų33.566%0.6619%0.193SC*.THydrogen-bonded Turntrans95.911.1172.500000115.5L162 R163 I164L162-G166 PolarHBondContact O-N 2.88Å; R163-G166 PolarHBondContact O-N 3.15Å; I164-G166 PolarHBondContact O-N 3.23Å
167V98.8Very high98.8Very high14 Ų1433.5 Ų33.59%0.08519%0.193CC..  trans-74.5128.5174.8-179.70000109.9V129 R133 L162 R163 D171 L174V129-V167 HydrophobicContact CG1-CG2 4.03Å; V129-V167 HydrophobicContact CG2-CG2 4.2Å; R133-V167 VanDerWaalsContact NH2-CG1 3.26Å; L162-V167 HydrophobicContact CB-CB 4.28Å; L162-V167 HydrophobicContact CB-CG2 4.29Å; L162-V167 HydrophobicContact CD2-CG2 4.05Å; L162-V167 WeakPolarHBondContact O-CB 3.38Å; L162-V167 PolarHBondContact O-N 3.4Å; R163-V167 WeakPolarHBondContact CD-O 3.47Å; R163-V167 PolarHBondContact NH1-O 2.86Å; V167-D171 HydrophobicContact CG1-CB 3.58Å; V167-L174 HydrophobicContact CB-CD1 4.02Å; V167-L174 HydrophobicContact CG1-CD1 3.66Å; V167-L174 HydrophobicContact CG1-CG 3.92Å
168D98.5Very high98.8Very high92 Ų9235.4 Ų35.449%0.49220%0.2SC..  trans-62.9143-177.2-167.4-84.1000112.9D170 D171D168-D170 PolarHBondContact O-N 2.93Å; D168-D170 WeakPolarHBondContact OD1-CB 3.18Å; D168-D170 PolarHBondContact OD1-N 3.01Å; D168-D171 WeakPolarHBondContact O-CB 3.38Å; D168-D171 PolarHBondContact O-N 2.68Å
169P98.5Very high98.8Very high23 Ų2340.1 Ų40.115%0.14923%0.225CC..THydrogen-bonded Turntrans-66.4-17.6-178.329-33.3000113.4R163 R178 E263R163-P169 VanDerWaalsContact CZ-CD 3.41Å; P169-R178 PolarHBondContact O-NH1 2.58Å; P169-R178 PolarHBondContact O-NH2 2.89Å; P169-E263 HydrophobicContact CB-CG 4.49Å
170D98.6Very high98.8Very high120 Ų12041 Ų4164%0.64223%0.23SC*.THydrogen-bonded Turntrans-92.33.6175.5-63.8-35.2000112.9D168D168-D170 PolarHBondContact O-N 2.93Å; D168-D170 WeakPolarHBondContact OD1-CB 3.18Å; D168-D170 PolarHBondContact OD1-N 3.01Å
171D98.8Very high98.8Very high36 Ų3641 Ų4119%0.19323%0.23CC..SBendtrans-55.1132.9169.2-177.6-75.6000110.3R133 V167 D168 D173 L174 V175R133-D171 IonicContact CZ-OD1 3.6Å; R133-D171 IonicContact CZ-OD2 2.64Å; R133-D171 IonicContact NH1-OD1 2.83Å; R133-D171 PolarHBondContact NH1-OD1 3.31Å; R133-D171 IonicContact NH1-OD2 2.92Å; R133-D171 PolarHBondContact NH1-OD2 2.89Å; R133-D171 IonicContact NH2-OD1 3.68Å; R133-D171 IonicContact NH2-OD2 3.86Å; R133-D171 PolarHBondContact NH2-OD2 3.28Å; V167-D171 HydrophobicContact CG1-CB 3.58Å; D168-D171 WeakPolarHBondContact O-CB 3.38Å; D168-D171 PolarHBondContact O-N 2.68Å; D171-D173 PolarHBondContact O-N 2.89Å; D171-D173 VanDerWaalsContact O-N 3.1Å; D171-D173 WeakPolarHBondContact OD1-CB 3.47Å; D171-D173 PolarHBondContact OD1-N 3.19Å; D171-L174 HydrophobicContact CB-CB 4.26Å; D171-L174 HydrophobicContact CB-CG 4.28Å; D171-L174 PolarHBondContact O-N 3.45Å; D171-V175 WeakPolarHBondContact O-CG2 3.3Å; D171-V175 PolarHBondContact O-N 3.5Å
172P98.8Very high98.7Very high91 Ų9143.8 Ų43.859%0.59124%0.243SC*.Hα-helixtrans-55.1-33.8-175.3-2835000114.6R176P172-R176 WeakPolarHBondContact O-CG 3.46Å; P172-R176 PolarHBondContact O-N 2.65Å; P172-R176 PolarHBondContact O-NH1 2.68Å
173D98.7Very high98.7Very high32 Ų3247.2 Ų47.217%0.17128%0.278CS..Hα-helixtrans-72.8-36.8178.2-67.2-13.2000111.3R133 Q136 D171 R176 A177R133-D173 IonicContact CZ-OD2 3.58Å; R133-D173 VanDerWaalsContact NH1-CG 3.29Å; R133-D173 IonicContact NH1-OD2 2.84Å; R133-D173 PolarHBondContact NH1-OD2 3.08Å; Q136-D173 PolarHBondContact NE2-O 2.98Å; D171-D173 PolarHBondContact O-N 2.89Å; D171-D173 VanDerWaalsContact O-N 3.1Å; D171-D173 WeakPolarHBondContact OD1-CB 3.47Å; D171-D173 PolarHBondContact OD1-N 3.19Å; D173-R176 IonicContact OD1-CZ 2.79Å; D173-R176 IonicContact OD1-NH1 2.92Å; D173-R176 PolarHBondContact OD1-NH1 2.98Å; D173-R176 IonicContact OD1-NH2 2.71Å; D173-R176 PolarHBondContact OD1-NH2 3.15Å; D173-A177 WeakPolarHBondContact O-CB 3.35Å; D173-A177 PolarHBondContact O-N 3.37Å
174L98.9Very high98.7Very high0 Ų048.9 Ų48.90%029%0.286CS..Hα-helixtrans-74.7-33.6177-67.8-159.6000112.6Y159 L162 R163 V167 D171 A177 R178Y159-L174 HydrophobicContact CD2-CB 4.25Å; Y159-L174 HydrophobicContact CD2-CD2 3.87Å; Y159-L174 HydrophobicContact CD2-CG 4.48Å; Y159-L174 HydrophobicContact CE2-CB 3.78Å; Y159-L174 HydrophobicContact CE2-CD1 4.3Å; Y159-L174 HydrophobicContact CE2-CD2 4.21Å; Y159-L174 HydrophobicContact CE2-CG 4.33Å; Y159-L174 WeakPolarHBondContact CE2-O 3.14Å; L162-L174 HydrophobicContact CB-CD1 4.27Å; L162-L174 HydrophobicContact CB-CD2 3.83Å; L162-L174 HydrophobicContact CD1-CD2 3.53Å; L162-L174 HydrophobicContact CG-CD2 4.32Å; R163-L174 HydrophobicContact CG-CD1 3.95Å; V167-L174 HydrophobicContact CB-CD1 4.02Å; V167-L174 HydrophobicContact CG1-CD1 3.66Å; V167-L174 HydrophobicContact CG1-CG 3.92Å; D171-L174 HydrophobicContact CB-CB 4.26Å; D171-L174 HydrophobicContact CB-CG 4.28Å; D171-L174 PolarHBondContact O-N 3.45Å; L174-A177 PolarHBondContact O-N 2.73Å; L174-R178 WeakPolarHBondContact O-CB 3.35Å; L174-R178 PolarHBondContact O-N 3.04Å
175V98.9Very high98.7Very high46 Ų4649.1 Ų49.128%0.27930%0.296SS..Hα-helixtrans-60.6-46.5171173.20000110.5D171 A177 R178 N179D171-V175 WeakPolarHBondContact O-CG2 3.3Å; D171-V175 PolarHBondContact O-N 3.5Å; V175-A177 PolarHBondContact O-N 2.84Å; V175-R178 PolarHBondContact O-N 3.09Å; V175-N179 WeakPolarHBondContact O-CB 3.22Å; V175-N179 PolarHBondContact O-N 3.23Å; V175-N179 PolarHBondContact O-ND2 2.92Å
176R98.8Very high98.7Very high98 Ų9847.9 Ų47.937%0.3729%0.29SS..Hα-helixtrans-61.3-44.4175.4-68.2-167.8-43.7-88.63.5111.8P172 D173 N179 N180P172-R176 WeakPolarHBondContact O-CG 3.46Å; P172-R176 PolarHBondContact O-N 2.65Å; P172-R176 PolarHBondContact O-NH1 2.68Å; D173-R176 IonicContact OD1-CZ 2.79Å; D173-R176 IonicContact OD1-NH1 2.92Å; D173-R176 PolarHBondContact OD1-NH1 2.98Å; D173-R176 IonicContact OD1-NH2 2.71Å; D173-R176 PolarHBondContact OD1-NH2 3.15Å; R176-N179 PolarHBondContact O-N 2.9Å; R176-N180 VanDerWaalsContact O-CB 3.31Å; R176-N180 WeakPolarHBondContact O-CB 3.22Å; R176-N180 PolarHBondContact O-N 3.42Å
177A98.9Very high98.7Very high0 Ų044.9 Ų44.90%026%0.258CS..Hα-helixtrans-62.2-45.4178.700000112.9G140 W142 T155 Y159 D173 L174 V175 N180 L181G140-A177 WeakPolarHBondContact O-CA 3.42Å; G140-A177 VanDerWaalsContact O-CB 3.3Å; G140-A177 WeakPolarHBondContact O-CB 3.5Å; W142-A177 HydrophobicContact CH2-CB 4.34Å; W142-A177 HydrophobicContact CZ3-CB 3.66Å; T155-A177 HydrophobicContact CG2-CB 4.35Å; T155-A177 WeakPolarHBondContact CG2-O 3.48Å; Y159-A177 HydrophobicContact CD2-CB 3.93Å; D173-A177 WeakPolarHBondContact O-CB 3.35Å; D173-A177 PolarHBondContact O-N 3.37Å; L174-A177 PolarHBondContact O-N 2.73Å; V175-A177 PolarHBondContact O-N 2.84Å; A177-N180 WeakPolarHBondContact O-CB 3.5Å; A177-N180 PolarHBondContact O-N 3.27Å; A177-L181 WeakPolarHBondContact O-CB 3.45Å; A177-L181 PolarHBondContact O-N 3.01Å
178R98.9Very high98.7Very high40 Ų4044.6 Ų44.615%0.15126%0.257CS..Hα-helixtrans-63.1-43.7177.2-176.2167.761.3-112.73.9111.3Y159 P169 L174 V175 N180 L181 H182 E263Y159-R178 HydrophobicContact CE2-CB 3.88Å; Y159-R178 PolarHBondContact OH-NH1 3.06Å; P169-R178 PolarHBondContact O-NH1 2.58Å; P169-R178 PolarHBondContact O-NH2 2.89Å; L174-R178 WeakPolarHBondContact O-CB 3.35Å; L174-R178 PolarHBondContact O-N 3.04Å; V175-R178 PolarHBondContact O-N 3.09Å; R178-N180 VanDerWaalsContact C-N 3.35Å; R178-N180 PolarHBondContact O-N 3.19Å; R178-L181 PolarHBondContact O-N 2.82Å; R178-H182 WeakPolarHBondContact O-CB 3.29Å; R178-H182 PolarHBondContact O-CD2 3.27Å; R178-H182 PolarHBondContact O-N 3.41Å; R178-E263 WeakPolarHBondContact CD-O 3.46Å
179N98.8Very high98.7Very high99 Ų9940.4 Ų40.453%0.52924%0.236SC..Hα-helixtrans-62.8-41.6175.3-68.3-16.6000111.9V175 R176 H182 G183V175-N179 WeakPolarHBondContact O-CB 3.22Å; V175-N179 PolarHBondContact O-N 3.23Å; V175-N179 PolarHBondContact O-ND2 2.92Å; R176-N179 PolarHBondContact O-N 2.9Å; N179-H182 PolarHBondContact O-N 3.39Å; N179-G183 PolarHBondContact O-N 3.48Å
180N98.6Very high98.7Very high20 Ų2039.3 Ų39.311%0.10723%0.228CC..Hα-helixtrans-61.6-46175.2-175.5-73.8000111.6D139 R176 A177 R178 G183 K184D139-N180 PolarHBondContact O-ND2 2.92Å; D139-N180 PolarHBondContact OD1-ND2 2.98Å; D139-N180 PolarHBondContact OD2-ND2 3.38Å; D139-N180 VanDerWaalsContact OD2-ND2 3.11Å; R176-N180 VanDerWaalsContact O-CB 3.31Å; R176-N180 WeakPolarHBondContact O-CB 3.22Å; R176-N180 PolarHBondContact O-N 3.42Å; A177-N180 WeakPolarHBondContact O-CB 3.5Å; A177-N180 PolarHBondContact O-N 3.27Å; R178-N180 VanDerWaalsContact C-N 3.35Å; R178-N180 PolarHBondContact O-N 3.19Å; N180-G183 PolarHBondContact O-N 3.4Å; N180-K184 PolarHBondContact ND2-NZ 2.9Å; N180-K184 PolarHBondContact O-N 3.21Å; N180-K184 PolarHBondContact OD1-NZ 3.44Å
181L98.9Very high98.7Very high1 Ų133.6 Ų33.61%0.00520%0.198CC..Hα-helixtrans-61.6-47.6177.2175.159.9000111.6V152 T155 A156 A177 R178 G183 K184 G185 G186 L264V152-L181 HydrophobicContact CG1-CD1 3.86Å; T155-L181 HydrophobicContact CG2-CB 3.98Å; A156-L181 HydrophobicContact CB-CD1 4.01Å; A156-L181 HydrophobicContact CB-CD2 4.12Å; A177-L181 WeakPolarHBondContact O-CB 3.45Å; A177-L181 PolarHBondContact O-N 3.01Å; R178-L181 PolarHBondContact O-N 2.82Å; L181-G183 VanDerWaalsContact C-N 3.33Å; L181-G183 PolarHBondContact O-N 2.75Å; L181-K184 PolarHBondContact O-N 2.9Å; L181-G185 PolarHBondContact O-N 2.96Å; L181-G186 PolarHBondContact O-N 3.45Å; L181-L264 HydrophobicContact CD2-CD2 3.97Å
182H98.8Very high98.7Very high59 Ų5933 Ų3327%0.27320%0.197SC..Hα-helixtrans-66.3-36.2178.9-74.2-161.4000111.7R178 N179 K184 G185 E263 F265 V266R178-H182 WeakPolarHBondContact O-CB 3.29Å; R178-H182 PolarHBondContact O-CD2 3.27Å; R178-H182 PolarHBondContact O-N 3.41Å; N179-H182 PolarHBondContact O-N 3.39Å; H182-K184 PolarHBondContact O-N 3.47Å; H182-K184 VanDerWaalsContact O-N 3.12Å; H182-G185 PolarHBondContact O-N 3.31Å; H182-E263 PolarHBondContact NE2-O 3.42Å; H182-F265 PolarHBondContact CE1-O 3.18Å; H182-F265 PolarHBondContact NE2-O 2.56Å; H182-V266 HydrophobicContact CB-CG2 3.94Å
183G98.3Very high98.7Very high71 Ų7129.7 Ų29.773%0.73217%0.172SC*.Hα-helixtrans-60.7-17.2171.500000114.3N179 N180 L181N179-G183 PolarHBondContact O-N 3.48Å; N180-G183 PolarHBondContact O-N 3.4Å; L181-G183 VanDerWaalsContact C-N 3.33Å; L181-G183 PolarHBondContact O-N 2.75Å
184K98.4Very high98.7Very high63 Ų6328.2 Ų28.227%0.27416%0.164SC..THydrogen-bonded Turntrans-102.16.4174.5-66.3176.1172.366.90113.8S150 V152 N180 L181 H182S150-K184 WeakPolarHBondContact O-CE 3.37Å; S150-K184 WeakPolarHBondContact OG-CE 3.46Å; S150-K184 PolarHBondContact OG-NZ 3.12Å; V152-K184 HydrophobicContact CG2-CB 3.64Å; V152-K184 HydrophobicContact CG2-CD 4.13Å; N180-K184 PolarHBondContact ND2-NZ 2.9Å; N180-K184 PolarHBondContact O-N 3.21Å; N180-K184 PolarHBondContact OD1-NZ 3.44Å; L181-K184 PolarHBondContact O-N 2.9Å; H182-K184 PolarHBondContact O-N 3.47Å; H182-K184 VanDerWaalsContact O-N 3.12Å
185G98.3Very high98.7Very high37 Ų3728.2 Ų28.238%0.38116%0.164SC..THydrogen-bonded Turntrans96.77.3179.400000115.2L181 H182L181-G185 PolarHBondContact O-N 2.96Å; H182-G185 PolarHBondContact O-N 3.31Å
186G98.6Very high98.7Very high0 Ų026.2 Ų26.20%015%0.152CC..  trans74.2-176.1178.300000114.1L181 V188 G189L181-G186 PolarHBondContact O-N 3.45Å; G186-V188 PolarHBondContact O-N 3.5Å; G186-V188 VanDerWaalsContact O-N 3.17Å; G186-G189 PolarHBondContact O-N 3.46Å
187A98.8Very high98.7Very high0 Ų021.8 Ų21.80%014%0.135CC..G310 helixtrans-73-2.6-173.100000115.3A156 G189 I190 L198 L264 F265A156-A187 HydrophobicContact CB-CB 4.42Å; A187-G189 VanDerWaalsContact C-N 3.26Å; A187-G189 PolarHBondContact O-N 3.1Å; A187-I190 WeakPolarHBondContact O-CB 3.22Å; A187-I190 WeakPolarHBondContact O-CG2 3.31Å; A187-I190 PolarHBondContact O-N 3.17Å; A187-L198 HydrophobicContact CB-CD1 4.05Å; A187-L264 HydrophobicContact CB-CB 4.01Å; A187-L264 WeakPolarHBondContact CB-O 3.08Å; A187-L264 PolarHBondContact N-O 3.06Å; A187-F265 HydrophobicContact CB-CD1 4.12Å; A187-F265 HydrophobicContact CB-CE1 3.75Å; A187-F265 HydrophobicContact CB-CZ 4.14Å
188V98.6Very high98.7Very high8 Ų821.8 Ų21.85%0.04814%0.135CC..G310 helixtrans-67.7-26.8173.8-71.40000113.4G186 F265 I272 Q277G186-V188 PolarHBondContact O-N 3.5Å; G186-V188 VanDerWaalsContact O-N 3.17Å; V188-F265 HydrophobicContact CG1-CD1 3.69Å; V188-F265 HydrophobicContact CG1-CE1 3.91Å; V188-I272 HydrophobicContact CG1-CD1 4.04Å; V188-I272 HydrophobicContact CG1-CG2 4.01Å; V188-Q277 HydrophobicContact CB-CG 4.25Å; V188-Q277 HydrophobicContact CG1-CG 4.25Å
189G98.1Very high98.7Very high5 Ų519.9 Ų19.95%0.05213%0.128CC..G310 helixtrans-92.413.4176.900000113.9G186 A187 V281 A282G186-G189 PolarHBondContact O-N 3.46Å; A187-G189 VanDerWaalsContact C-N 3.26Å; A187-G189 PolarHBondContact O-N 3.1Å; G189-V281 CarbonylContact O-C 3.46Å; G189-V281 WeakPolarHBondContact O-CA 3.39Å; G189-A282 PolarHBondContact O-N 2.89Å
190I98.9Very high98.7Very high0 Ų015.1 Ų15.10%010%0.103CC..  trans-66.8143.1179.7-161.2173.5000110.8V152 F153 A156 L157 A187 K195 L198 Y204V152-I190 HydrophobicContact CG1-CB 3.91Å; V152-I190 HydrophobicContact CG1-CG1 4.2Å; F153-I190 HydrophobicContact CD2-CD1 4.28Å; F153-I190 HydrophobicContact CD2-CG1 4.11Å; A156-I190 HydrophobicContact CB-CD1 3.85Å; L157-I190 HydrophobicContact CD2-CD1 4.38Å; L157-I190 HydrophobicContact CG-CD1 4.34Å; A187-I190 WeakPolarHBondContact O-CB 3.22Å; A187-I190 WeakPolarHBondContact O-CG2 3.31Å; A187-I190 PolarHBondContact O-N 3.17Å; I190-K195 HydrophobicContact CG2-CB 4.41Å; I190-K195 HydrophobicContact CG2-CG 3.58Å; I190-K195 WeakPolarHBondContact O-CE 3.42Å; I190-K195 WeakPolarHBondContact O-CG 3.41Å; I190-L198 HydrophobicContact CD1-CD1 3.81Å; I190-L198 HydrophobicContact CD1-CG 4.38Å; I190-L198 HydrophobicContact CG2-CD1 4.38Å; I190-Y204 HydrophobicContact CG2-CE2 4.4Å
191P98.9Very high98.7Very high0 Ų014.2 Ų14.20%010%0.098CC..  trans-56.9163.2174-28.437.1000114.4F153 W193 G194 K195 V281 D285 V521F153-P191 HydrophobicContact CB-CG 3.9Å; F153-P191 HydrophobicContact CG-CG 4.2Å; P191-W193 VanDerWaalsContact C-N 3.31Å; P191-W193 PolarHBondContact O-N 3.05Å; P191-G194 WeakPolarHBondContact O-CA 3.44Å; P191-G194 PolarHBondContact O-N 2.84Å; P191-K195 PolarHBondContact O-N 3Å; P191-V281 HydrophobicContact CB-CG1 4.3Å; P191-V281 HydrophobicContact CG-CG1 3.97Å; P191-D285 HydrophobicContact CG-CB 3.47Å; P191-D285 VanDerWaalsContact CG-CB 3.47Å; P191-V521 HydrophobicContact CB-CG1 3.74Å; P191-V521 HydrophobicContact CG-CG1 3.62Å
192S98.6Very high98.7Very high24 Ų2415.8 Ų15.817%0.16811%0.106CC..Hα-helixtrans-56.6-39.2-171.163.10000114.1G194 K195 F196 P518 E520S192-G194 VanDerWaalsContact C-N 3.29Å; S192-G194 PolarHBondContact O-N 2.68Å; S192-K195 WeakPolarHBondContact O-CB 3.32Å; S192-K195 PolarHBondContact O-N 3.06Å; S192-F196 PolarHBondContact O-N 2.7Å; S192-P518 PolarHBondContact OG-O 3.39Å; S192-E520 WeakPolarHBondContact CB-OE2 3.2Å; S192-E520 PolarHBondContact N-OE2 3.47Å; S192-E520 PolarHBondContact OG-OE2 3.49Å
193W98.8Very high98.7Very high21 Ų2113 Ų138%0.089%0.093CC..Hα-helixtrans-65-33.7175.7-77.729.5000112.3F104 F153 P191 F196 W197 V237 Y238 M241 I339 F522F104-W193 HydrophobicContact CD2-CZ3 4.5Å; F104-W193 HydrophobicContact CE2-CZ3 4.2Å; F153-W193 HydrophobicContact CE2-CB 4.21Å; F153-W193 HydrophobicContact CZ-CB 3.91Å; P191-W193 VanDerWaalsContact C-N 3.31Å; P191-W193 PolarHBondContact O-N 3.05Å; W193-F196 WeakPolarHBondContact O-CB 3.11Å; W193-W197 PolarHBondContact O-N 3.41Å; W193-V237 HydrophobicContact CH2-CB 4.41Å; W193-V237 HydrophobicContact CH2-CG1 3.88Å; W193-V237 HydrophobicContact CH2-CG2 4.32Å; W193-V237 HydrophobicContact CZ2-CB 4.36Å; W193-V237 HydrophobicContact CZ2-CG1 3.72Å; W193-Y238 HydrophobicContact CZ2-CE2 4.32Å; W193-Y238 AromaticContact NE1-CE2 3.89Å; W193-Y238 AromaticContact NE1-CZ 3.54Å; W193-Y238 PolarHBondContact NE1-OH 2.85Å; W193-M241 HydrophobicContact CD2-CE 4Å; W193-M241 HydrophobicContact CG-CE 4.05Å; W193-I339 HydrophobicContact CE3-CD1 4.27Å; W193-I339 HydrophobicContact CH2-CD1 4.1Å; W193-I339 HydrophobicContact CZ3-CD1 3.42Å; W193-I339 VanDerWaalsContact CZ3-CD1 3.42Å; W193-F522 HydrophobicContact CD2-CE2 4.35Å; W193-F522 AromaticContact CE3-CE2 3.94Å; W193-F522 HydrophobicContact CE3-CE2 3.94Å; W193-F522 AromaticContact CH2-CE2 3.86Å; W193-F522 HydrophobicContact CH2-CE2 3.86Å; W193-F522 HydrophobicContact CZ2-CE2 4.28Å; W193-F522 AromaticContact CZ3-CE2 3.65Å; W193-F522 HydrophobicContact CZ3-CE2 3.65Å; W193-F522 HydrophobicContact CZ3-CZ 4.24Å
194G98.9Very high98.7Very high0 Ų09.8 Ų9.80%06%0.059CC..Hα-helixtrans-71.3-40.3172.600000112.1F153 P191 S192 F196 W197 L198F153-G194 VanDerWaalsContact CE2-N 3.35Å; P191-G194 WeakPolarHBondContact O-CA 3.44Å; P191-G194 PolarHBondContact O-N 2.84Å; S192-G194 VanDerWaalsContact C-N 3.29Å; S192-G194 PolarHBondContact O-N 2.68Å; G194-F196 VanDerWaalsContact C-N 3.27Å; G194-F196 PolarHBondContact O-N 2.69Å; G194-W197 PolarHBondContact O-N 2.93Å; G194-L198 WeakPolarHBondContact O-CB 3.28Å; G194-L198 WeakPolarHBondContact O-CG 3.22Å; G194-L198 PolarHBondContact O-N 3.47Å
195K98.9Very high98.8Very high1 Ų18.4 Ų8.40%0.0046%0.057CC..Hα-helixtrans-58.1-43.5173.2-58.1178.8-168.8-175.60110.8I190 P191 S192 L198 A199 Y204 L209 Q277 R278 N280I190-K195 HydrophobicContact CG2-CB 4.41Å; I190-K195 HydrophobicContact CG2-CG 3.58Å; I190-K195 WeakPolarHBondContact O-CE 3.42Å; I190-K195 WeakPolarHBondContact O-CG 3.41Å; P191-K195 PolarHBondContact O-N 3Å; S192-K195 WeakPolarHBondContact O-CB 3.32Å; S192-K195 PolarHBondContact O-N 3.06Å; K195-L198 PolarHBondContact O-N 2.62Å; K195-A199 WeakPolarHBondContact O-CB 3.37Å; K195-A199 PolarHBondContact O-N 3.41Å; K195-Y204 HydrophobicContact CB-CD1 4.28Å; K195-Y204 HydrophobicContact CB-CE1 3.97Å; K195-Y204 HydrophobicContact CD-CE1 4.26Å; K195-Y204 HydrophobicContact CG-CE1 4.06Å; K195-Y204 HydrophobicContact CG-CE2 4.16Å; K195-L209 HydrophobicContact CB-CB 3.83Å; K195-L209 HydrophobicContact CB-CD2 3.79Å; K195-L209 HydrophobicContact CB-CG 4.47Å; K195-L209 HydrophobicContact CD-CB 3.84Å; K195-L209 HydrophobicContact CG-CB 4.46Å; K195-Q277 PolarHBondContact NZ-O 2.74Å; K195-R278 PolarHBondContact NZ-O 3.35Å; K195-N280 WeakPolarHBondContact CE-O 3.22Å; K195-N280 PolarHBondContact NZ-O 2.89Å
196F98.9Very high98.8Very high3 Ų37.4 Ų7.41%0.0134%0.042CC..Hα-helixtrans-56.3-54.4175.9170.8-93.2000111.5S192 W193 G194 L198 A199 V200 W206 L212 M241 C244 I343S192-F196 PolarHBondContact O-N 2.7Å; W193-F196 WeakPolarHBondContact O-CB 3.11Å; G194-F196 VanDerWaalsContact C-N 3.27Å; G194-F196 PolarHBondContact O-N 2.69Å; F196-L198 PolarHBondContact O-N 3.33Å; F196-A199 PolarHBondContact O-N 3.47Å; F196-V200 HydrophobicContact CD1-CG2 4.48Å; F196-V200 HydrophobicContact CE1-CG2 4.01Å; F196-V200 HydrophobicContact CE2-CG2 4.04Å; F196-V200 HydrophobicContact CZ-CG2 3.76Å; F196-V200 WeakPolarHBondContact O-CG2 3.34Å; F196-V200 PolarHBondContact O-N 2.66Å; F196-W206 AromaticContact CD2-CH2 3.69Å; F196-W206 HydrophobicContact CD2-CH2 3.69Å; F196-W206 AromaticContact CD2-CZ3 3.84Å; F196-W206 HydrophobicContact CD2-CZ3 3.84Å; F196-W206 AromaticContact CE2-CH2 3.69Å; F196-W206 HydrophobicContact CE2-CH2 3.69Å; F196-W206 HydrophobicContact CE2-CZ3 4.22Å; F196-L212 HydrophobicContact CD2-CD1 4.11Å; F196-M241 HydrophobicContact CD1-CE 3.86Å; F196-M241 HydrophobicContact CD1-CG 4.1Å; F196-M241 HydrophobicContact CD1-SD 4.4Å; F196-M241 HydrophobicContact CD2-CB 4.02Å; F196-M241 HydrophobicContact CD2-CG 4.01Å; F196-M241 HydrophobicContact CE1-CE 4.25Å; F196-M241 HydrophobicContact CE1-CG 3.86Å; F196-M241 VanDerWaalsContact CE2-CA 3.49Å; F196-M241 HydrophobicContact CE2-CB 3.65Å; F196-M241 HydrophobicContact CE2-CG 3.76Å; F196-M241 HydrophobicContact CG-CE 4.27Å; F196-M241 HydrophobicContact CG-CG 4.18Å; F196-M241 HydrophobicContact CG-SD 4.32Å; F196-M241 HydrophobicContact CZ-CB 4Å; F196-M241 HydrophobicContact CZ-CG 3.69Å; F196-C244 HydrophobicContact CE2-CB 3.84Å; F196-C244 HydrophobicContact CZ-CB 3.95Å; F196-I343 HydrophobicContact CE1-CD1 3.89Å; F196-I343 HydrophobicContact CE1-CG1 4.25Å; F196-I343 HydrophobicContact CE1-CG2 4.42Å; F196-I343 HydrophobicContact CZ-CD1 4.26Å; F196-I343 HydrophobicContact CZ-CG2 3.98Å
197W98.9Very high98.8Very high5 Ų511.1 Ų11.12%0.0196%0.059CC..Hα-helixtrans-63.3-41.5-178.3-79.1121.5000113.1G108 I111 L157 W193 G194 A199 V200 L201 T342 I343G108-W197 VanDerWaalsContact CA-CZ2 3.49Å; G108-W197 WeakPolarHBondContact O-CZ3 3.28Å; I111-W197 HydrophobicContact CB-CE3 4.26Å; I111-W197 HydrophobicContact CD1-CB 3.86Å; I111-W197 HydrophobicContact CD1-CE3 4.35Å; I111-W197 HydrophobicContact CD1-CG 4.45Å; I111-W197 HydrophobicContact CG2-CE3 4.05Å; I111-W197 HydrophobicContact CG2-CZ3 4.43Å; L157-W197 HydrophobicContact CD2-CB 4.22Å; W193-W197 PolarHBondContact O-N 3.41Å; G194-W197 PolarHBondContact O-N 2.93Å; W197-A199 VanDerWaalsContact C-N 3.33Å; W197-A199 PolarHBondContact O-N 3.47Å; W197-V200 PolarHBondContact O-N 2.79Å; W197-L201 PolarHBondContact O-N 2.91Å; W197-T342 HydrophobicContact CH2-CG2 3.88Å; W197-I343 HydrophobicContact CH2-CD1 4.31Å; W197-I343 HydrophobicContact CH2-CG1 3.49Å; W197-I343 VanDerWaalsContact CH2-CG1 3.49Å; W197-I343 HydrophobicContact CZ2-CD1 4.02Å; W197-I343 HydrophobicContact CZ2-CG1 3.65Å; W197-I343 HydrophobicContact CZ3-CG1 4.47Å
198L98.9Very high98.8Very high0 Ų011.1 Ų11.10%06%0.059CC..Hα-helixtrans-70.2-29.2177.3-64.2-173.6000112.5L157 A187 I190 G194 K195 F196 L201 N202 V203 Y204 L264L157-L198 HydrophobicContact CD2-CD2 4.03Å; L157-L198 HydrophobicContact CD2-CG 4.34Å; A187-L198 HydrophobicContact CB-CD1 4.05Å; I190-L198 HydrophobicContact CD1-CD1 3.81Å; I190-L198 HydrophobicContact CD1-CG 4.38Å; I190-L198 HydrophobicContact CG2-CD1 4.38Å; G194-L198 WeakPolarHBondContact O-CB 3.28Å; G194-L198 WeakPolarHBondContact O-CG 3.22Å; G194-L198 PolarHBondContact O-N 3.47Å; K195-L198 PolarHBondContact O-N 2.62Å; F196-L198 PolarHBondContact O-N 3.33Å; L198-L201 PolarHBondContact O-N 3.08Å; L198-N202 PolarHBondContact O-N 3.49Å; L198-N202 VanDerWaalsContact O-N 3.16Å; L198-V203 HydrophobicContact CB-CG2 3.83Å; L198-V203 HydrophobicContact CD2-CG2 3.71Å; L198-V203 HydrophobicContact CG-CG2 4.24Å; L198-V203 PolarHBondContact O-N 2.85Å; L198-Y204 HydrophobicContact CB-CG 4.37Å; L198-Y204 PolarHBondContact O-N 2.9Å; L198-Y204 VanDerWaalsContact O-N 3.13Å; L198-L264 HydrophobicContact CD2-CD1 4.32Å
199A98.9Very high98.8Very high0 Ų011 Ų110%06%0.059CC..Hα-helixtrans-72.7-39.3173.600000112.7K195 F196 W197 L201 N202 Y204 W206 L209 S250K195-A199 WeakPolarHBondContact O-CB 3.37Å; K195-A199 PolarHBondContact O-N 3.41Å; F196-A199 PolarHBondContact O-N 3.47Å; W197-A199 VanDerWaalsContact C-N 3.33Å; W197-A199 PolarHBondContact O-N 3.47Å; A199-L201 VanDerWaalsContact C-N 3.31Å; A199-L201 PolarHBondContact O-N 3.15Å; A199-N202 PolarHBondContact O-N 2.87Å; A199-Y204 VanDerWaalsContact CA-O 3.24Å; A199-Y204 WeakPolarHBondContact CA-O 3.45Å; A199-W206 HydrophobicContact CB-CD2 3.66Å; A199-W206 HydrophobicContact CB-CE3 3.84Å; A199-W206 HydrophobicContact CB-CG 4.09Å; A199-W206 HydrophobicContact CB-CH2 4.34Å; A199-W206 HydrophobicContact CB-CZ2 4.18Å; A199-W206 HydrophobicContact CB-CZ3 4.18Å; A199-L209 HydrophobicContact CB-CD2 4.16Å; A199-S250 PolarHBondContact O-OG 2.92Å; A199-S250 VanDerWaalsContact O-OG 3.1Å
200V98.8Very high98.8Very high0 Ų011.3 Ų11.30%06%0.059CC..Hα-helixtrans-59.8-42.1169.9166.70000110.8I111 I115 F196 W197 N202 W206 L249 S250 A251 L346I111-V200 HydrophobicContact CG2-CG1 4.09Å; I115-V200 HydrophobicContact CD1-CG1 3.38Å; I115-V200 WeakPolarHBondContact CD1-O 3.44Å; F196-V200 HydrophobicContact CD1-CG2 4.48Å; F196-V200 HydrophobicContact CE1-CG2 4.01Å; F196-V200 HydrophobicContact CE2-CG2 4.04Å; F196-V200 HydrophobicContact CZ-CG2 3.76Å; F196-V200 WeakPolarHBondContact O-CG2 3.34Å; F196-V200 PolarHBondContact O-N 2.66Å; W197-V200 PolarHBondContact O-N 2.79Å; V200-N202 PolarHBondContact O-N 3.5Å; V200-W206 HydrophobicContact CG2-CH2 3.69Å; V200-W206 HydrophobicContact CG2-CZ2 3.61Å; V200-L249 HydrophobicContact CG1-CD2 4.2Å; V200-S250 CarbonylContact O-C 3.59Å; V200-S250 WeakPolarHBondContact O-CA 3.42Å; V200-A251 PolarHBondContact O-N 2.78Å; V200-L346 HydrophobicContact CG1-CD2 3.61Å
201L98.9Very high98.8Very high0 Ų011.3 Ų11.30%06%0.059CC..THydrogen-bonded Turntrans-72.8-5.7175-17260.5000113.7I111 T160 I164 W197 L198 A199 V203 I257 L260I111-L201 HydrophobicContact CD1-CD2 4.42Å; I111-L201 HydrophobicContact CG1-CD2 4.2Å; I111-L201 HydrophobicContact CG2-CB 4.05Å; I111-L201 HydrophobicContact CG2-CD1 4.32Å; T160-L201 HydrophobicContact CG2-CD2 3.36Å; I164-L201 HydrophobicContact CD1-CD1 4.46Å; I164-L201 HydrophobicContact CD1-CD2 4.36Å; W197-L201 PolarHBondContact O-N 2.91Å; L198-L201 PolarHBondContact O-N 3.08Å; A199-L201 VanDerWaalsContact C-N 3.31Å; A199-L201 PolarHBondContact O-N 3.15Å; L201-V203 VanDerWaalsContact C-N 3.3Å; L201-V203 HydrophobicContact CB-CG2 4.32Å; L201-V203 HydrophobicContact CD2-CG1 4.31Å; L201-V203 HydrophobicContact CD2-CG2 4.09Å; L201-V203 HydrophobicContact CG-CG1 4.17Å; L201-V203 HydrophobicContact CG-CG2 4.34Å; L201-V203 PolarHBondContact O-N 3.47Å; L201-I257 HydrophobicContact CD1-CD1 4.49Å; L201-I257 HydrophobicContact CD1-CG1 4.29Å; L201-I257 HydrophobicContact CG-CG1 4.48Å; L201-I257 WeakPolarHBondContact O-CD1 3.28Å; L201-L260 HydrophobicContact CD2-CD1 3.9Å
202N98.9Very high98.8Very high35 Ų3512.3 Ų12.319%0.1876%0.064CC..THydrogen-bonded Turntrans64.428.4-177.5-159.15.8000114.4L198 A199 V200 A251 I257 R261L198-N202 PolarHBondContact O-N 3.49Å; L198-N202 VanDerWaalsContact O-N 3.16Å; A199-N202 PolarHBondContact O-N 2.87Å; V200-N202 PolarHBondContact O-N 3.5Å; N202-A251 HydrophobicContact CB-CB 4.19Å; N202-A251 WeakPolarHBondContact CB-O 3.47Å; N202-A251 PolarHBondContact ND2-O 3.33Å; N202-I257 HydrophobicContact CB-CG2 4.4Å; N202-R261 VanDerWaalsContact CG-NH2 3.28Å; N202-R261 VanDerWaalsContact O-CZ 3.25Å; N202-R261 PolarHBondContact O-NE 2.88Å; N202-R261 PolarHBondContact O-NH2 3.44Å; N202-R261 PolarHBondContact OD1-NH2 3.23Å
203V98.8Very high98.8Very high0 Ų012 Ų120%06%0.06CC..SBendtrans-111.63.1173.2-56.10000112.6L198 L201 I257 L260 R261 L264 F265 F269L198-V203 HydrophobicContact CB-CG2 3.83Å; L198-V203 HydrophobicContact CD2-CG2 3.71Å; L198-V203 HydrophobicContact CG-CG2 4.24Å; L198-V203 PolarHBondContact O-N 2.85Å; L201-V203 VanDerWaalsContact C-N 3.3Å; L201-V203 HydrophobicContact CB-CG2 4.32Å; L201-V203 HydrophobicContact CD2-CG1 4.31Å; L201-V203 HydrophobicContact CD2-CG2 4.09Å; L201-V203 HydrophobicContact CG-CG1 4.17Å; L201-V203 HydrophobicContact CG-CG2 4.34Å; L201-V203 PolarHBondContact O-N 3.47Å; V203-I257 HydrophobicContact CG1-CB 4.35Å; V203-I257 HydrophobicContact CG1-CG1 4.46Å; V203-I257 HydrophobicContact CG1-CG2 3.88Å; V203-L260 HydrophobicContact CB-CB 4.5Å; V203-L260 HydrophobicContact CG1-CB 3.76Å; V203-L260 HydrophobicContact CG1-CD1 4.25Å; V203-R261 HydrophobicContact CB-CG 4.2Å; V203-R261 HydrophobicContact CG1-CG 4.24Å; V203-L264 HydrophobicContact CB-CD1 4.41Å; V203-L264 HydrophobicContact CG2-CD1 3.89Å; V203-F265 WeakPolarHBondContact O-CE2 3.46Å; V203-F265 WeakPolarHBondContact O-CZ 3.38Å; V203-F269 VanDerWaalsContact O-CE2 3.29Å; V203-F269 WeakPolarHBondContact O-CE2 3.36Å
204Y98.9Very high98.8Very high4 Ų411 Ų112%0.0166%0.056CC..SBendtrans-142.3147.5172.6-171.1-75.9000108I190 K195 L198 A199 G208 F265 W274 Q277I190-Y204 HydrophobicContact CG2-CE2 4.4Å; K195-Y204 HydrophobicContact CB-CD1 4.28Å; K195-Y204 HydrophobicContact CB-CE1 3.97Å; K195-Y204 HydrophobicContact CD-CE1 4.26Å; K195-Y204 HydrophobicContact CG-CE1 4.06Å; K195-Y204 HydrophobicContact CG-CE2 4.16Å; L198-Y204 HydrophobicContact CB-CG 4.37Å; L198-Y204 PolarHBondContact O-N 2.9Å; L198-Y204 VanDerWaalsContact O-N 3.13Å; A199-Y204 VanDerWaalsContact CA-O 3.24Å; A199-Y204 WeakPolarHBondContact CA-O 3.45Å; Y204-G208 WeakPolarHBondContact CE1-O 3.45Å; Y204-G208 PolarHBondContact OH-O 3.1Å; Y204-F265 HydrophobicContact CD2-CE1 4.17Å; Y204-F265 HydrophobicContact CD2-CZ 4.2Å; Y204-W274 HydrophobicContact CD1-CE3 4.25Å; Y204-W274 HydrophobicContact CD1-CZ3 4.02Å; Y204-W274 HydrophobicContact CD2-CE3 4.43Å; Y204-W274 HydrophobicContact CD2-CH2 4.21Å; Y204-W274 AromaticContact CD2-CZ3 3.54Å; Y204-W274 HydrophobicContact CD2-CZ3 3.54Å; Y204-W274 AromaticContact CE1-CE3 3.99Å; Y204-W274 HydrophobicContact CE1-CE3 3.99Å; Y204-W274 HydrophobicContact CE1-CZ3 4.04Å; Y204-W274 HydrophobicContact CE2-CE3 4.22Å; Y204-W274 AromaticContact CE2-CZ3 3.59Å; Y204-W274 HydrophobicContact CE2-CZ3 3.59Å; Y204-W274 HydrophobicContact CG-CE3 4.42Å; Y204-W274 HydrophobicContact CG-CH2 4.31Å; Y204-W274 AromaticContact CG-CZ3 3.74Å; Y204-W274 HydrophobicContact CG-CZ3 3.74Å; Y204-W274 AromaticContact CZ-CE3 3.95Å; Y204-W274 AromaticContact CZ-CZ3 3.81Å; Y204-Q277 VanDerWaalsContact OH-CB 3.22Å; Y204-Q277 WeakPolarHBondContact OH-CB 3.36Å
205S98.8Very high98.8Very high33 Ų3311.3 Ų11.323%0.2316%0.058CC..  trans-78.9136.3-179.5-176.40000112.6E207 G208 W274S205-E207 PolarHBondContact O-N 3.28Å; S205-E207 VanDerWaalsContact O-N 3.13Å; S205-E207 PolarHBondContact OG-N 2.95Å; S205-E207 VanDerWaalsContact OG-N 3.16Å; S205-G208 PolarHBondContact O-N 3.27Å; S205-W274 VanDerWaalsContact CB-CD1 3.49Å
206W98.8Very high98.7Very high16 Ų1613.1 Ų13.16%0.0617%0.067CC..G310 helixtrans-55-26.2167.2-77.6113.2000113.6F196 A199 V200 G208 L209 C244 Y245 L249 S250F196-W206 AromaticContact CD2-CH2 3.69Å; F196-W206 HydrophobicContact CD2-CH2 3.69Å; F196-W206 AromaticContact CD2-CZ3 3.84Å; F196-W206 HydrophobicContact CD2-CZ3 3.84Å; F196-W206 AromaticContact CE2-CH2 3.69Å; F196-W206 HydrophobicContact CE2-CH2 3.69Å; F196-W206 HydrophobicContact CE2-CZ3 4.22Å; A199-W206 HydrophobicContact CB-CD2 3.66Å; A199-W206 HydrophobicContact CB-CE3 3.84Å; A199-W206 HydrophobicContact CB-CG 4.09Å; A199-W206 HydrophobicContact CB-CH2 4.34Å; A199-W206 HydrophobicContact CB-CZ2 4.18Å; A199-W206 HydrophobicContact CB-CZ3 4.18Å; V200-W206 HydrophobicContact CG2-CH2 3.69Å; V200-W206 HydrophobicContact CG2-CZ2 3.61Å; W206-G208 PolarHBondContact O-N 2.74Å; W206-L209 HydrophobicContact CE3-CD1 4.33Å; W206-L209 HydrophobicContact CE3-CD2 3.9Å; W206-L209 HydrophobicContact CE3-CG 4.45Å; W206-L209 HydrophobicContact CZ3-CD2 4.1Å; W206-C244 HydrophobicContact CH2-CB 4.38Å; W206-Y245 HydrophobicContact CD2-CD2 4.5Å; W206-Y245 AromaticContact CE3-CD2 3.48Å; W206-Y245 HydrophobicContact CE3-CD2 3.48Å; W206-Y245 VanDerWaalsContact CE3-CD2 3.48Å; W206-Y245 HydrophobicContact CE3-CE2 4.13Å; W206-Y245 HydrophobicContact CE3-CG 4.42Å; W206-Y245 AromaticContact CZ3-CD2 3.68Å; W206-Y245 HydrophobicContact CZ3-CD2 3.68Å; W206-Y245 HydrophobicContact CZ3-CG 4.34Å; W206-L249 VanDerWaalsContact CZ2-O 3.23Å; W206-L249 WeakPolarHBondContact CZ2-O 3.25Å; W206-L249 PolarHBondContact NE1-O 2.92Å; W206-S250 PolarHBondContact NE1-OG 3.33Å
207E98.5Very high98.7Very high79 Ų7913.3 Ų13.337%0.3697%0.068SC..G310 helixtrans-77.3-11.2176.4-65.1-54131.300113.2S205 R248 R278S205-E207 PolarHBondContact O-N 3.28Å; S205-E207 VanDerWaalsContact O-N 3.13Å; S205-E207 PolarHBondContact OG-N 2.95Å; S205-E207 VanDerWaalsContact OG-N 3.16Å; E207-R248 IonicContact OE1-CZ 3.95Å; E207-R248 IonicContact OE1-NE 3.9Å; E207-R248 IonicContact OE1-NH2 2.93Å; E207-R248 PolarHBondContact OE1-NH2 3.28Å; E207-R278 PolarHBondContact O-NE 2.89Å; E207-R278 PolarHBondContact O-NH2 3.22Å; E207-R278 IonicContact OE2-NH2 3.31Å; E207-R278 PolarHBondContact OE2-NH2 3.47Å; E207-R278 VanDerWaalsContact OE2-NH2 3.1Å
208G98.6Very high98.7Very high0 Ų015.8 Ų15.80%08%0.081CC..G310 helixtrans-90.68179.400000115.5Y204 S205 W206 W274 Q277 R278Y204-G208 WeakPolarHBondContact CE1-O 3.45Å; Y204-G208 PolarHBondContact OH-O 3.1Å; S205-G208 PolarHBondContact O-N 3.27Å; W206-G208 PolarHBondContact O-N 2.74Å; G208-W274 WeakPolarHBondContact CA-O 3.28Å; G208-Q277 CarbonylContact O-C 3.51Å; G208-R278 WeakPolarHBondContact O-CA 3.25Å; G208-R278 PolarHBondContact O-N 3.01Å
209L98.6Very high98.7Very high6 Ų619 Ų193%0.03110%0.095CC..SBendtrans-127.5154.2174.260.786.7000110.9K195 A199 W206 Y245K195-L209 HydrophobicContact CB-CB 3.83Å; K195-L209 HydrophobicContact CB-CD2 3.79Å; K195-L209 HydrophobicContact CB-CG 4.47Å; K195-L209 HydrophobicContact CD-CB 3.84Å; K195-L209 HydrophobicContact CG-CB 4.46Å; A199-L209 HydrophobicContact CB-CD2 4.16Å; W206-L209 HydrophobicContact CE3-CD1 4.33Å; W206-L209 HydrophobicContact CE3-CD2 3.9Å; W206-L209 HydrophobicContact CE3-CG 4.45Å; W206-L209 HydrophobicContact CZ3-CD2 4.1Å; L209-Y245 HydrophobicContact CD1-CD2 3.74Å; L209-Y245 HydrophobicContact CD1-CE2 3.55Å
210N98.8Very high98.6Very high10 Ų1022 Ų225%0.05312%0.115CC..  trans-64.4145.1176.4-74.9-52.6000110.6L212 R278 N279 Y298 N302N210-L212 PolarHBondContact O-N 2.87Å; N210-R278 PolarHBondContact ND2-O 2.89Å; N210-N279 PolarHBondContact ND2-OD1 3.47Å; N210-Y298 HydrophobicContact CB-CD1 3.71Å; N210-Y298 HydrophobicContact CB-CD2 4.05Å; N210-Y298 HydrophobicContact CB-CE1 3.63Å; N210-Y298 HydrophobicContact CB-CE2 3.93Å; N210-Y298 HydrophobicContact CB-CG 3.95Å; N210-N302 PolarHBondContact OD1-ND2 2.74Å
211T98.7Very high98.5Very high1 Ų126 Ų261%0.00614%0.142CC..  trans-54.7139.7179.3-179.60000112L213 Y245 Y298 L301 N302 E305T211-L213 PolarHBondContact OG1-N 3.29Å; T211-L213 VanDerWaalsContact OG1-N 3.12Å; T211-Y245 WeakPolarHBondContact CA-OH 3.26Å; T211-Y245 WeakPolarHBondContact OG1-CE1 3.34Å; T211-Y298 WeakPolarHBondContact O-CE1 3.41Å; T211-L301 HydrophobicContact CG2-CB 3.66Å; T211-N302 PolarHBondContact N-OD1 2.85Å; T211-E305 HydrophobicContact CG2-CB 4.36Å; T211-E305 PolarHBondContact OG1-OE2 3.41Å
212L98.6Very high98.4Very high20 Ų2035.7 Ų35.711%0.10518%0.179CC..  trans-87.27.6173.3-59.6-171.6000112.7F196 N210 Y238 M241 S242 Y245F196-L212 HydrophobicContact CD2-CD1 4.11Å; N210-L212 PolarHBondContact O-N 2.87Å; L212-Y238 HydrophobicContact CD2-CD1 4.37Å; L212-Y238 HydrophobicContact CD2-CE1 4.18Å; L212-M241 HydrophobicContact CD1-CB 3.67Å; L212-S242 PolarHBondContact O-OG 2.97Å; L212-Y245 HydrophobicContact CB-CD1 4.17Å; L212-Y245 HydrophobicContact CB-CG 4.05Å; L212-Y245 HydrophobicContact CD1-CG 4.31Å; L212-Y245 HydrophobicContact CG-CD2 4.22Å; L212-Y245 HydrophobicContact CG-CG 4.09Å
213L98.3Very high98.3Very high17 Ų1737.2 Ų37.29%0.08919%0.186CC..  trans34.967.8177.6-167.967.3000115.2T211 E215 M216 L301 Y304T211-L213 PolarHBondContact OG1-N 3.29Å; T211-L213 VanDerWaalsContact OG1-N 3.12Å; L213-E215 PolarHBondContact O-N 3.37Å; L213-E215 VanDerWaalsContact O-N 3.07Å; L213-M216 HydrophobicContact CD2-CB 4.12Å; L213-M216 HydrophobicContact CG-CB 4.23Å; L213-M216 VanDerWaalsContact O-CB 3.22Å; L213-M216 WeakPolarHBondContact O-CB 3.48Å; L213-M216 PolarHBondContact O-N 2.93Å; L213-L301 HydrophobicContact CD1-CD2 3.94Å; L213-L301 HydrophobicContact CD2-CD1 3.93Å; L213-L301 HydrophobicContact CD2-CD2 3.53Å; L213-L301 HydrophobicContact CD2-CG 4.31Å; L213-L301 HydrophobicContact CG-CD2 4.3Å; L213-Y304 HydrophobicContact CD1-CD1 3.99Å; L213-Y304 HydrophobicContact CD1-CE1 4.14Å
214P98.8Very high98Very high0 Ų042.1 Ų42.10%022%0.218CC..G310 helixtrans-62.6-19.2-178.9-4.89000114M216 W217 S242 Y245 A246 R313 A316 L320P214-M216 PolarHBondContact O-N 3.47Å; P214-W217 PolarHBondContact O-N 3.08Å; P214-S242 WeakPolarHBondContact CG-O 3.27Å; P214-Y245 HydrophobicContact CG-CD1 4.26Å; P214-A246 HydrophobicContact CB-CB 4.17Å; P214-A246 HydrophobicContact CG-CB 3.68Å; P214-R313 VanDerWaalsContact CA-NH2 3.35Å; P214-R313 VanDerWaalsContact CD-NH1 3.29Å; P214-A316 HydrophobicContact CB-CB 4.46Å; P214-A316 WeakPolarHBondContact O-CB 3.42Å; P214-L320 HydrophobicContact CB-CD1 3.5Å; P214-L320 VanDerWaalsContact CB-CD1 3.5Å
215E98.8Very high97.9Very high8 Ų842.5 Ų42.54%0.03722%0.222CC..G310 helixtrans-68.5-14.7175.4-69.989.1173.300113.3L213 W217 L218 Y304 L312 R313 A316L213-E215 PolarHBondContact O-N 3.37Å; L213-E215 VanDerWaalsContact O-N 3.07Å; E215-W217 PolarHBondContact O-N 3.2Å; E215-W217 VanDerWaalsContact O-N 3.09Å; E215-L218 WeakPolarHBondContact O-CB 3.24Å; E215-L218 PolarHBondContact O-N 3.4Å; E215-Y304 HydrophobicContact CG-CE1 4.46Å; E215-Y304 PolarHBondContact OE1-OH 2.9Å; E215-L312 HydrophobicContact CG-CB 4.03Å; E215-R313 IonicContact OE1-CZ 3.85Å; E215-R313 IonicContact OE1-NE 3.49Å; E215-R313 IonicContact OE1-NH1 3.24Å; E215-R313 PolarHBondContact OE1-NH1 3.18Å; E215-R313 VanDerWaalsContact OE1-NH1 3.07Å; E215-R313 IonicContact OE1-NH2 3Å; E215-R313 PolarHBondContact OE1-NH2 3.28Å; E215-R313 VanDerWaalsContact OE1-NH2 3.12Å; E215-R313 IonicContact OE2-CZ 3.98Å; E215-R313 IonicContact OE2-NH1 2.67Å; E215-R313 PolarHBondContact OE2-NH1 2.91Å; E215-R313 IonicContact OE2-NH2 3.27Å; E215-R313 PolarHBondContact OE2-NH2 3.17Å; E215-A316 HydrophobicContact CG-CB 4.47Å
216M98.3Very high97.9Very high39 Ų3941.1 Ų41.119%0.19221%0.212CC..G310 helixtrans-56.4-26.6176.2-173.2170.75800112.5L213 P214 L218 F219 P227L213-M216 HydrophobicContact CD2-CB 4.12Å; L213-M216 HydrophobicContact CG-CB 4.23Å; L213-M216 VanDerWaalsContact O-CB 3.22Å; L213-M216 WeakPolarHBondContact O-CB 3.48Å; L213-M216 PolarHBondContact O-N 2.93Å; P214-M216 PolarHBondContact O-N 3.47Å; M216-L218 VanDerWaalsContact C-N 3.29Å; M216-L218 PolarHBondContact O-N 3.2Å; M216-F219 HydrophobicContact CB-CE2 4.4Å; M216-F219 HydrophobicContact CG-CD2 4.13Å; M216-F219 HydrophobicContact CG-CE2 4.22Å; M216-F219 WeakPolarHBondContact O-CB 3.17Å; M216-F219 PolarHBondContact O-N 2.96Å; M216-P227 HydrophobicContact CE-CG 4.29Å; M216-P227 HydrophobicContact CG-CG 4.1Å; M216-P227 WeakPolarHBondContact O-CD 3.21Å
217W98.6Very high97.9Very high7 Ų740.4 Ų40.43%0.02721%0.209CC..G310 helixtrans-76-12.8176.5-69.276.9000114.2P214 E215 P227 R235 L239 E319 L320 H323 Y435P214-W217 PolarHBondContact O-N 3.08Å; E215-W217 PolarHBondContact O-N 3.2Å; E215-W217 VanDerWaalsContact O-N 3.09Å; W217-P227 HydrophobicContact CD2-CB 3.89Å; W217-P227 HydrophobicContact CD2-CG 3.7Å; W217-P227 HydrophobicContact CE3-CB 4.01Å; W217-P227 HydrophobicContact CE3-CG 4.22Å; W217-P227 HydrophobicContact CG-CG 3.87Å; W217-P227 HydrophobicContact CH2-CB 3.84Å; W217-P227 HydrophobicContact CZ2-CB 3.7Å; W217-P227 HydrophobicContact CZ2-CG 4.2Å; W217-P227 HydrophobicContact CZ3-CB 4Å; W217-R235 HydrophobicContact CH2-CB 4.37Å; W217-R235 HydrophobicContact CZ2-CB 4.43Å; W217-L239 HydrophobicContact CD2-CD1 4.15Å; W217-L239 HydrophobicContact CE3-CD1 4.1Å; W217-L239 HydrophobicContact CH2-CB 3.75Å; W217-L239 HydrophobicContact CH2-CD1 3.63Å; W217-L239 HydrophobicContact CH2-CD2 4.19Å; W217-L239 HydrophobicContact CH2-CG 4.06Å; W217-L239 HydrophobicContact CZ2-CB 3.49Å; W217-L239 VanDerWaalsContact CZ2-CB 3.49Å; W217-L239 HydrophobicContact CZ2-CD1 3.67Å; W217-L239 HydrophobicContact CZ2-CG 4.12Å; W217-L239 HydrophobicContact CZ3-CD1 3.85Å; W217-E319 HydrophobicContact CB-CG 4.41Å; W217-L320 HydrophobicContact CB-CD2 4.16Å; W217-L320 HydrophobicContact CD2-CD2 3.75Å; W217-L320 HydrophobicContact CG-CD2 3.47Å; W217-L320 VanDerWaalsContact CG-CD2 3.47Å; W217-L320 HydrophobicContact CG-CG 4.45Å; W217-H323 HydrophobicContact CZ3-CB 4.4Å; W217-H323 AromaticContact CZ3-ND1 3.68Å; W217-Y435 HydrophobicContact CE3-CE2 4.41Å; W217-Y435 HydrophobicContact CZ3-CE2 4.02Å
218L98.7Very high97.9Very high57 Ų5737.4 Ų37.430%0.29820%0.197SC..G310 helixtrans-94.2-5.7174.7-59.5-179.6000112.9E215 M216 M315 A316 E319E215-L218 WeakPolarHBondContact O-CB 3.24Å; E215-L218 PolarHBondContact O-N 3.4Å; M216-L218 VanDerWaalsContact C-N 3.29Å; M216-L218 PolarHBondContact O-N 3.2Å; L218-M315 HydrophobicContact CD1-CB 3.73Å; L218-M315 HydrophobicContact CD2-CB 4.27Å; L218-A316 HydrophobicContact CD1-CB 3.94Å; L218-A316 HydrophobicContact CG-CB 4.08Å; L218-E319 HydrophobicContact CD2-CB 4.02Å; L218-E319 HydrophobicContact CD2-CG 4.36Å
219F98.4Very high97.9Very high67 Ų6738.6 Ų38.629%0.29420%0.204SC..SBendtrans-63.4149.8179.2-70-13.1000110.7M216 S221 M223 H226M216-F219 HydrophobicContact CB-CE2 4.4Å; M216-F219 HydrophobicContact CG-CD2 4.13Å; M216-F219 HydrophobicContact CG-CE2 4.22Å; M216-F219 WeakPolarHBondContact O-CB 3.17Å; M216-F219 PolarHBondContact O-N 2.96Å; F219-S221 PolarHBondContact O-N 3.02Å; F219-M223 HydrophobicContact CB-CB 4.2Å; F219-M223 HydrophobicContact CB-SD 3.79Å; F219-M223 HydrophobicContact CD1-SD 4.05Å; F219-M223 HydrophobicContact CD2-CE 3.89Å; F219-M223 HydrophobicContact CD2-CG 4.24Å; F219-M223 HydrophobicContact CD2-SD 3.39Å; F219-M223 WeakPolarHBondContact CD2-SD 3.48Å; F219-M223 HydrophobicContact CE1-SD 4.47Å; F219-M223 HydrophobicContact CE2-CE 3.74Å; F219-M223 HydrophobicContact CE2-SD 3.88Å; F219-M223 HydrophobicContact CG-CE 4.41Å; F219-M223 HydrophobicContact CG-SD 3.48Å; F219-M223 WeakPolarHBondContact CG-SD 3.32Å; F219-M223 HydrophobicContact CZ-CE 4.14Å; F219-M223 HydrophobicContact CZ-SD 4.4Å; F219-H226 PolarHBondContact O-CD2 3.21Å; F219-H226 PolarHBondContact O-NE2 3.48Å
220P98Very high97.9Very high64 Ų6438.8 Ų38.842%0.41621%0.205SC..  trans-55.3139.2168.6-23.534000110.5W222 M223P220-W222 HydrophobicContact CB-CD2 4.26Å; P220-W222 HydrophobicContact CB-CG 4.3Å; P220-W222 HydrophobicContact CB-CZ2 4.09Å; P220-W222 HydrophobicContact CG-CZ2 4.17Å; P220-W222 PolarHBondContact O-N 2.91Å; P220-M223 VanDerWaalsContact O-CB 3.24Å; P220-M223 WeakPolarHBondContact O-CB 3.38Å; P220-M223 PolarHBondContact O-N 3.09Å
221S96.1Very high97.9Very high82 Ų8239 Ų3957%0.57321%0.205SC*.THydrogen-bonded Turntrans-61.3-15.5-173.358.20000115.3F219F219-S221 PolarHBondContact O-N 3.02Å
222W95.8Very high97.9Very high204 Ų20439 Ų3977%0.77321%0.205SC*.THydrogen-bonded Turntrans-84-10.8174.959.4-102.2000113.8P220P220-W222 HydrophobicContact CB-CD2 4.26Å; P220-W222 HydrophobicContact CB-CG 4.3Å; P220-W222 HydrophobicContact CB-CZ2 4.09Å; P220-W222 HydrophobicContact CG-CZ2 4.17Å; P220-W222 PolarHBondContact O-N 2.91Å
223M96.8Very high97.9Very high67 Ų6740 Ų4033%0.3321%0.209SC..SBendtrans-68.1138.4-176.5-170.2164.3175.400111F219 P220 A225 H226F219-M223 HydrophobicContact CB-CB 4.2Å; F219-M223 HydrophobicContact CB-SD 3.79Å; F219-M223 HydrophobicContact CD1-SD 4.05Å; F219-M223 HydrophobicContact CD2-CE 3.89Å; F219-M223 HydrophobicContact CD2-CG 4.24Å; F219-M223 HydrophobicContact CD2-SD 3.39Å; F219-M223 WeakPolarHBondContact CD2-SD 3.48Å; F219-M223 HydrophobicContact CE1-SD 4.47Å; F219-M223 HydrophobicContact CE2-CE 3.74Å; F219-M223 HydrophobicContact CE2-SD 3.88Å; F219-M223 HydrophobicContact CG-CE 4.41Å; F219-M223 HydrophobicContact CG-SD 3.48Å; F219-M223 WeakPolarHBondContact CG-SD 3.32Å; F219-M223 HydrophobicContact CZ-CE 4.14Å; F219-M223 HydrophobicContact CZ-SD 4.4Å; P220-M223 VanDerWaalsContact O-CB 3.24Å; P220-M223 WeakPolarHBondContact O-CB 3.38Å; P220-M223 PolarHBondContact O-N 3.09Å; M223-A225 PolarHBondContact O-N 3.22Å; M223-H226 VanDerWaalsContact O-CB 3.22Å; M223-H226 WeakPolarHBondContact O-CB 3.35Å; M223-H226 PolarHBondContact O-N 3.13Å
224P94.1Very high97.9Very high103 Ų10339.5 Ų39.567%0.66921%0.207SC*.THydrogen-bonded Turntrans-54.6139.2174.2-25.534.8000111.5H226P224-H226 PolarHBondContact O-N 2.58Å
225A96.2Very high97.9Very high13 Ų1339.7 Ų39.711%0.10721%0.208CC..THydrogen-bonded Turntrans6611.3-175.400000115.6M223 L513 L516M223-A225 PolarHBondContact O-N 3.22Å; A225-L513 HydrophobicContact CB-CD2 3.77Å; A225-L516 HydrophobicContact CB-CD1 3.86Å
226H98.7Very high97.9Very high3 Ų339.7 Ų39.71%0.01421%0.208CC..  trans-54.1134.9171.6-179.1-87.5000110.4F219 M223 P224 S228 T229 Y435F219-H226 PolarHBondContact O-CD2 3.21Å; F219-H226 PolarHBondContact O-NE2 3.48Å; M223-H226 VanDerWaalsContact O-CB 3.22Å; M223-H226 WeakPolarHBondContact O-CB 3.35Å; M223-H226 PolarHBondContact O-N 3.13Å; P224-H226 PolarHBondContact O-N 2.58Å; H226-S228 PolarHBondContact CE1-OG 2.68Å; H226-S228 WeakPolarHBondContact ND1-CB 3.26Å; H226-S228 PolarHBondContact ND1-N 2.71Å; H226-S228 VanDerWaalsContact ND1-N 3.18Å; H226-S228 PolarHBondContact ND1-OG 3.03Å; H226-S228 PolarHBondContact O-N 3.02Å; H226-T229 PolarHBondContact O-N 2.99Å; H226-T229 PolarHBondContact O-OG1 2.74Å; H226-Y435 AromaticContact CE1-CZ 3.76Å; H226-Y435 PolarHBondContact CE1-OH 3.22Å
227P98.8Very high98Very high1 Ų138.1 Ų38.11%0.00620%0.201CC..G310 helixtrans-55.5-32-170-29.537000114.8M216 W217 T229 L230 R235M216-P227 HydrophobicContact CE-CG 4.29Å; M216-P227 HydrophobicContact CG-CG 4.1Å; M216-P227 WeakPolarHBondContact O-CD 3.21Å; W217-P227 HydrophobicContact CD2-CB 3.89Å; W217-P227 HydrophobicContact CD2-CG 3.7Å; W217-P227 HydrophobicContact CE3-CB 4.01Å; W217-P227 HydrophobicContact CE3-CG 4.22Å; W217-P227 HydrophobicContact CG-CG 3.87Å; W217-P227 HydrophobicContact CH2-CB 3.84Å; W217-P227 HydrophobicContact CZ2-CB 3.7Å; W217-P227 HydrophobicContact CZ2-CG 4.2Å; W217-P227 HydrophobicContact CZ3-CB 4Å; P227-T229 PolarHBondContact O-N 2.83Å; P227-T229 VanDerWaalsContact O-N 3.14Å; P227-L230 PolarHBondContact O-N 2.91Å; P227-L230 VanDerWaalsContact O-N 3.14Å; P227-R235 WeakPolarHBondContact O-CD 3.39Å
228S98.6Very high98Very high16 Ų1639 Ų3911%0.11220%0.204CC..G310 helixtrans-61.1-20.2176.771.20000114.7H226 Y435 R508H226-S228 PolarHBondContact CE1-OG 2.68Å; H226-S228 WeakPolarHBondContact ND1-CB 3.26Å; H226-S228 PolarHBondContact ND1-N 2.71Å; H226-S228 VanDerWaalsContact ND1-N 3.18Å; H226-S228 PolarHBondContact ND1-OG 3.03Å; H226-S228 PolarHBondContact O-N 3.02Å; S228-Y435 VanDerWaalsContact CB-CD1 3.42Å; S228-Y435 VanDerWaalsContact CB-CD2 3.48Å; S228-R508 WeakPolarHBondContact O-CD 3.46Å; S228-R508 PolarHBondContact O-NH1 2.76Å
229T98.7Very high98Very high25 Ų2536.3 Ų36.315%0.15319%0.19CC..G310 helixtrans-96.2-10.2-179.369.10000113.6H226 P227 R508 G509H226-T229 PolarHBondContact O-N 2.99Å; H226-T229 PolarHBondContact O-OG1 2.74Å; P227-T229 PolarHBondContact O-N 2.83Å; P227-T229 VanDerWaalsContact O-N 3.14Å; T229-R508 HydrophobicContact CG2-CB 4.48Å; T229-G509 PolarHBondContact O-N 2.76Å
230L98.8Very high98Very high10 Ų1033.1 Ų33.15%0.05218%0.176CC..SBendtrans-82.8157.2178.4-54.9-177.8000110.9P227 R235 L513 M526P227-L230 PolarHBondContact O-N 2.91Å; P227-L230 VanDerWaalsContact O-N 3.14Å; L230-R235 HydrophobicContact CB-CB 4.36Å; L230-R235 PolarHBondContact O-NH1 3.16Å; L230-L513 HydrophobicContact CD2-CD1 4.16Å; L230-M526 CarbonylContact C-O 3.54Å; L230-M526 WeakPolarHBondContact CA-O 3.28Å; L230-M526 WeakPolarHBondContact CB-O 3.49Å; L230-M526 HydrophobicContact CD1-CE 4.46Å; L230-M526 HydrophobicContact CD2-CE 4.06Å; L230-M526 WeakPolarHBondContact CD2-O 3.38Å
231W98.9Very high98.1Very high15 Ų1530.1 Ų30.16%0.05716%0.157CC..  trans-52.8141.7174.6-175.440.6000111.5H233 C234 R235 T503 I525 M526 W582 N698W231-H233 HydrophobicContact CD2-CB 3.82Å; W231-H233 AromaticContact CE2-CD2 3.75Å; W231-H233 HydrophobicContact CE3-CB 3.71Å; W231-H233 HydrophobicContact CH2-CB 3.48Å; W231-H233 VanDerWaalsContact CH2-CB 3.48Å; W231-H233 AromaticContact CH2-CD2 3.87Å; W231-H233 AromaticContact CH2-CG 3.85Å; W231-H233 HydrophobicContact CZ2-CB 3.6Å; W231-H233 AromaticContact CZ2-CD2 3.3Å; W231-H233 WeakPolarHBondContact CZ2-CD2 3.33Å; W231-H233 AromaticContact CZ2-CG 3.71Å; W231-H233 HydrophobicContact CZ3-CB 3.54Å; W231-H233 PolarHBondContact O-N 3.25Å; W231-C234 HydrophobicContact CB-CB 4.11Å; W231-C234 HydrophobicContact CE3-CB 4.19Å; W231-C234 WeakPolarHBondContact O-CB 3.32Å; W231-C234 PolarHBondContact O-N 3.3Å; W231-R235 PolarHBondContact O-N 3.25Å; W231-T503 PolarHBondContact NE1-OG1 2.86Å; W231-I525 VanDerWaalsContact CB-O 3.29Å; W231-I525 WeakPolarHBondContact CB-O 3.5Å; W231-I525 HydrophobicContact CE3-CB 4.24Å; W231-I525 HydrophobicContact CZ3-CB 4.4Å; W231-I525 HydrophobicContact CZ3-CG2 4.42Å; W231-M526 PolarHBondContact N-O 2.8Å; W231-W582 HydrophobicContact CZ2-CH2 4.1Å; W231-N698 WeakPolarHBondContact CH2-OD1 3.49Å; W231-N698 WeakPolarHBondContact CZ3-ND2 3.36Å; W231-N698 WeakPolarHBondContact CZ3-OD1 3.47Å
232C98.5Very high98.2Very high0 Ų026.3 Ų26.30%013%0.13CC..Hα-helixtrans-59.5-46.9-175.454.40000113C234 R235 Q236 I336 W452 Y504C232-C234 VanDerWaalsContact C-N 3.35Å; C232-C234 PolarHBondContact O-N 3.07Å; C232-R235 PolarHBondContact O-N 3.15Å; C232-Q236 WeakPolarHBondContact O-CB 3.42Å; C232-Q236 VanDerWaalsContact O-CG 3.24Å; C232-Q236 WeakPolarHBondContact O-CG 3.36Å; C232-Q236 PolarHBondContact O-N 2.98Å; C232-I336 HydrophobicContact CB-CD1 3.89Å; C232-I336 VanDerWaalsContact SG-CD1 3.53Å; C232-W452 HydrophobicContact CB-CH2 4.22Å; C232-W452 HydrophobicContact CB-CZ3 3.8Å; C232-Y504 VanDerWaalsContact SG-CB 3.56Å; C232-Y504 WeakPolarHBondContact SG-CD2 3.32Å; C232-Y504 VanDerWaalsContact SG-CG 3.52Å
233H98.6Very high98.3Very high41 Ų4117.3 Ų17.319%0.1910%0.096CC..Hα-helixtrans-60.9-43.5175.8-82.6-77.2000111.7W231 V237 Y504W231-H233 HydrophobicContact CD2-CB 3.82Å; W231-H233 AromaticContact CE2-CD2 3.75Å; W231-H233 HydrophobicContact CE3-CB 3.71Å; W231-H233 HydrophobicContact CH2-CB 3.48Å; W231-H233 VanDerWaalsContact CH2-CB 3.48Å; W231-H233 AromaticContact CH2-CD2 3.87Å; W231-H233 AromaticContact CH2-CG 3.85Å; W231-H233 HydrophobicContact CZ2-CB 3.6Å; W231-H233 AromaticContact CZ2-CD2 3.3Å; W231-H233 WeakPolarHBondContact CZ2-CD2 3.33Å; W231-H233 AromaticContact CZ2-CG 3.71Å; W231-H233 HydrophobicContact CZ3-CB 3.54Å; W231-H233 PolarHBondContact O-N 3.25Å; H233-V237 WeakPolarHBondContact O-CG2 3.49Å; H233-V237 PolarHBondContact O-N 3.21Å; H233-V237 VanDerWaalsContact O-N 3.1Å; H233-Y504 AromaticContact CD2-CE2 3.53Å; H233-Y504 AromaticContact NE2-CE2 3.34Å; H233-Y504 VanDerWaalsContact NE2-CE2 3.34Å; H233-Y504 WeakPolarHBondContact NE2-CE2 3.47Å; H233-Y504 AromaticContact NE2-CZ 3.39Å; H233-Y504 PolarHBondContact NE2-OH 2.69Å
234C98.5Very high98.4Very high8 Ų814.1 Ų14.15%0.0548%0.08CC..Hα-helixtrans-58.4-58.5175.3-179.20000111.1W231 C232 Q236 V237 Y238 I525W231-C234 HydrophobicContact CB-CB 4.11Å; W231-C234 HydrophobicContact CE3-CB 4.19Å; W231-C234 WeakPolarHBondContact O-CB 3.32Å; W231-C234 PolarHBondContact O-N 3.3Å; C232-C234 VanDerWaalsContact C-N 3.35Å; C232-C234 PolarHBondContact O-N 3.07Å; C234-Q236 VanDerWaalsContact C-N 3.32Å; C234-Q236 PolarHBondContact O-N 2.93Å; C234-V237 PolarHBondContact O-N 2.92Å; C234-Y238 VanDerWaalsContact O-CD2 3.32Å; C234-Y238 WeakPolarHBondContact O-CD2 3.46Å; C234-Y238 PolarHBondContact O-N 2.99Å; C234-I525 VanDerWaalsContact CB-O 3.31Å; C234-I525 WeakPolarHBondContact CB-O 3.21Å
235R98.8Very high98.7Very high3 Ų39.2 Ų9.21%0.0115%0.048CC..Hα-helixtrans-66.9-31.6-176.176-177.4-177.5-98.2-0.6113W217 P227 L230 W231 C232 V237 L239 Y435 E505W217-R235 HydrophobicContact CH2-CB 4.37Å; W217-R235 HydrophobicContact CZ2-CB 4.43Å; P227-R235 WeakPolarHBondContact O-CD 3.39Å; L230-R235 HydrophobicContact CB-CB 4.36Å; L230-R235 PolarHBondContact O-NH1 3.16Å; W231-R235 PolarHBondContact O-N 3.25Å; C232-R235 PolarHBondContact O-N 3.15Å; R235-V237 VanDerWaalsContact C-N 3.35Å; R235-L239 WeakPolarHBondContact O-CB 3.38Å; R235-L239 PolarHBondContact O-N 2.76Å; R235-Y435 PolarHBondContact NH2-O 3.16Å; R235-Y435 VanDerWaalsContact NH2-O 3.16Å; R235-E505 IonicContact CZ-OE1 3.88Å; R235-E505 IonicContact CZ-OE2 3.41Å; R235-E505 VanDerWaalsContact CZ-OE2 3.27Å; R235-E505 IonicContact NH1-OE1 2.68Å; R235-E505 IonicContact NH1-OE2 3.31Å; R235-E505 PolarHBondContact NH1-OE2 3.22Å; R235-E505 IonicContact NH2-OE1 3.24Å; R235-E505 PolarHBondContact NH2-OE1 3.01Å; R235-E505 IonicContact NH2-OE2 3.08Å; R235-E505 PolarHBondContact NH2-OE2 3.45Å
236Q98.9Very high98.8Very high8 Ų89.3 Ų9.34%0.0375%0.049CC..Hα-helixtrans-75-22.7179.1-73.6-62.2-14.400113.1C232 C234 P240 I336 S340 W452C232-Q236 WeakPolarHBondContact O-CB 3.42Å; C232-Q236 VanDerWaalsContact O-CG 3.24Å; C232-Q236 WeakPolarHBondContact O-CG 3.36Å; C232-Q236 PolarHBondContact O-N 2.98Å; C234-Q236 VanDerWaalsContact C-N 3.32Å; C234-Q236 PolarHBondContact O-N 2.93Å; Q236-P240 WeakPolarHBondContact O-CD 3.33Å; Q236-P240 WeakPolarHBondContact O-CG 3.45Å; Q236-I336 HydrophobicContact CB-CG2 3.81Å; Q236-I336 HydrophobicContact CG-CG2 4.15Å; Q236-S340 WeakPolarHBondContact O-CB 3.35Å; Q236-W452 HydrophobicContact CG-CH2 4.19Å; Q236-W452 HydrophobicContact CG-CZ2 4.01Å
237V98.9Very high98.8Very high7 Ų711.1 Ų11.14%0.0426%0.06CC..Hα-helixtrans-82-48.3168.2173.60000110.9W193 H233 C234 R235 L239 P240 M241 I339W193-V237 HydrophobicContact CH2-CB 4.41Å; W193-V237 HydrophobicContact CH2-CG1 3.88Å; W193-V237 HydrophobicContact CH2-CG2 4.32Å; W193-V237 HydrophobicContact CZ2-CB 4.36Å; W193-V237 HydrophobicContact CZ2-CG1 3.72Å; H233-V237 WeakPolarHBondContact O-CG2 3.49Å; H233-V237 PolarHBondContact O-N 3.21Å; H233-V237 VanDerWaalsContact O-N 3.1Å; C234-V237 PolarHBondContact O-N 2.92Å; R235-V237 VanDerWaalsContact C-N 3.35Å; V237-L239 VanDerWaalsContact C-N 3.27Å; V237-L239 PolarHBondContact O-N 3.34Å; V237-P240 VanDerWaalsContact O-CD 3.25Å; V237-P240 WeakPolarHBondContact O-CD 3.48Å; V237-P240 WeakPolarHBondContact O-CG 3.46Å; V237-M241 HydrophobicContact CG1-CE 3.49Å; V237-M241 VanDerWaalsContact CG1-CE 3.49Å; V237-M241 HydrophobicContact CG1-CG 4.26Å; V237-M241 HydrophobicContact CG1-SD 3.71Å; V237-M241 VanDerWaalsContact O-CG 3.29Å; V237-M241 WeakPolarHBondContact O-CG 3.22Å; V237-M241 PolarHBondContact O-N 3.38Å; V237-I339 HydrophobicContact CB-CG2 4.43Å; V237-I339 HydrophobicContact CG1-CG2 3.72Å; V237-I339 HydrophobicContact CG2-CB 4Å; V237-I339 HydrophobicContact CG2-CG2 3.85Å
238Y98.9Very high98.8Very high25 Ų2514.6 Ų14.610%0.0987%0.073CC..Hα-helixtrans-68.7-23.7-177.8-81.4-83.9000113.2W193 L212 C234 S242 P518W193-Y238 HydrophobicContact CZ2-CE2 4.32Å; W193-Y238 AromaticContact NE1-CE2 3.89Å; W193-Y238 AromaticContact NE1-CZ 3.54Å; W193-Y238 PolarHBondContact NE1-OH 2.85Å; L212-Y238 HydrophobicContact CD2-CD1 4.37Å; L212-Y238 HydrophobicContact CD2-CE1 4.18Å; C234-Y238 VanDerWaalsContact O-CD2 3.32Å; C234-Y238 WeakPolarHBondContact O-CD2 3.46Å; C234-Y238 PolarHBondContact O-N 2.99Å; Y238-S242 WeakPolarHBondContact O-CB 3.14Å; Y238-S242 PolarHBondContact O-N 3.09Å; Y238-S242 PolarHBondContact O-OG 2.81Å; Y238-P518 HydrophobicContact CE1-CG 4.28Å
239L98.9Very high98.8Very high0 Ų014 Ų140%07%0.069CC..Hα-helixtrans-55.8-65174.5168.566000112.2W217 R235 V237 S242 Y243 L320 H323 I324W217-L239 HydrophobicContact CD2-CD1 4.15Å; W217-L239 HydrophobicContact CE3-CD1 4.1Å; W217-L239 HydrophobicContact CH2-CB 3.75Å; W217-L239 HydrophobicContact CH2-CD1 3.63Å; W217-L239 HydrophobicContact CH2-CD2 4.19Å; W217-L239 HydrophobicContact CH2-CG 4.06Å; W217-L239 HydrophobicContact CZ2-CB 3.49Å; W217-L239 VanDerWaalsContact CZ2-CB 3.49Å; W217-L239 HydrophobicContact CZ2-CD1 3.67Å; W217-L239 HydrophobicContact CZ2-CG 4.12Å; W217-L239 HydrophobicContact CZ3-CD1 3.85Å; R235-L239 WeakPolarHBondContact O-CB 3.38Å; R235-L239 PolarHBondContact O-N 2.76Å; V237-L239 VanDerWaalsContact C-N 3.27Å; V237-L239 PolarHBondContact O-N 3.34Å; L239-S242 PolarHBondContact O-N 3.04Å; L239-Y243 PolarHBondContact O-N 2.87Å; L239-Y243 VanDerWaalsContact O-N 3.13Å; L239-L320 HydrophobicContact CD1-CB 4.03Å; L239-L320 HydrophobicContact CD1-CD2 3.53Å; L239-L320 HydrophobicContact CD1-CG 4.36Å; L239-H323 HydrophobicContact CD1-CB 3.9Å; L239-H323 HydrophobicContact CD2-CB 3.85Å; L239-I324 HydrophobicContact CD1-CG1 4.28Å; L239-I324 HydrophobicContact CD2-CG1 3.82Å; L239-I324 HydrophobicContact CG-CD1 4.36Å; L239-I324 HydrophobicContact CG-CG1 3.75Å
240P98.9Very high98.8Very high0 Ų015.1 Ų15.10%08%0.078CC..Hα-helixtrans-71.9-27.6179.533.2-40.7000112.5Q236 V237 S242 Y243 C244 I324 I343 N344 V347Q236-P240 WeakPolarHBondContact O-CD 3.33Å; Q236-P240 WeakPolarHBondContact O-CG 3.45Å; V237-P240 VanDerWaalsContact O-CD 3.25Å; V237-P240 WeakPolarHBondContact O-CD 3.48Å; V237-P240 WeakPolarHBondContact O-CG 3.46Å; P240-S242 VanDerWaalsContact C-N 3.34Å; P240-S242 PolarHBondContact O-N 3.49Å; P240-Y243 WeakPolarHBondContact O-CB 3.28Å; P240-Y243 PolarHBondContact O-N 3.32Å; P240-C244 PolarHBondContact O-N 3.18Å; P240-C244 PolarHBondContact O-SG 2.81Å; P240-C244 VanDerWaalsContact O-SG 3.41Å; P240-I324 HydrophobicContact CB-CD1 3.93Å; P240-I324 HydrophobicContact CB-CG1 4.34Å; P240-I343 HydrophobicContact CB-CB 3.81Å; P240-I343 HydrophobicContact CB-CG2 3.59Å; P240-I343 HydrophobicContact CG-CB 3.81Å; P240-I343 HydrophobicContact CG-CD1 4.47Å; P240-I343 HydrophobicContact CG-CG2 4.03Å; P240-N344 WeakPolarHBondContact CB-OD1 3.36Å; P240-N344 WeakPolarHBondContact CG-OD1 3.31Å; P240-V347 HydrophobicContact CB-CG2 4.26Å
241M98.9Very high98.8Very high2 Ų214.9 Ų14.91%0.018%0.077CC..Hα-helixtrans-60.4-45170.4-71.2-175.9167.800111.6W193 F196 L212 V237 Y243 C244 Y245 I343W193-M241 HydrophobicContact CD2-CE 4Å; W193-M241 HydrophobicContact CG-CE 4.05Å; F196-M241 HydrophobicContact CD1-CE 3.86Å; F196-M241 HydrophobicContact CD1-CG 4.1Å; F196-M241 HydrophobicContact CD1-SD 4.4Å; F196-M241 HydrophobicContact CD2-CB 4.02Å; F196-M241 HydrophobicContact CD2-CG 4.01Å; F196-M241 HydrophobicContact CE1-CE 4.25Å; F196-M241 HydrophobicContact CE1-CG 3.86Å; F196-M241 VanDerWaalsContact CE2-CA 3.49Å; F196-M241 HydrophobicContact CE2-CB 3.65Å; F196-M241 HydrophobicContact CE2-CG 3.76Å; F196-M241 HydrophobicContact CG-CE 4.27Å; F196-M241 HydrophobicContact CG-CG 4.18Å; F196-M241 HydrophobicContact CG-SD 4.32Å; F196-M241 HydrophobicContact CZ-CB 4Å; F196-M241 HydrophobicContact CZ-CG 3.69Å; L212-M241 HydrophobicContact CD1-CB 3.67Å; V237-M241 HydrophobicContact CG1-CE 3.49Å; V237-M241 VanDerWaalsContact CG1-CE 3.49Å; V237-M241 HydrophobicContact CG1-CG 4.26Å; V237-M241 HydrophobicContact CG1-SD 3.71Å; V237-M241 VanDerWaalsContact O-CG 3.29Å; V237-M241 WeakPolarHBondContact O-CG 3.22Å; V237-M241 PolarHBondContact O-N 3.38Å; M241-Y243 VanDerWaalsContact C-N 3.29Å; M241-Y243 PolarHBondContact O-N 3.33Å; M241-C244 PolarHBondContact O-N 2.6Å; M241-Y245 WeakPolarHBondContact O-CB 3.31Å; M241-Y245 PolarHBondContact O-N 3.41Å; M241-I343 HydrophobicContact CE-CD1 3.89Å; M241-I343 HydrophobicContact CG-CD1 3.54Å
242S98.9Very high98.7Very high1 Ų122.6 Ų22.61%0.00711%0.114CC..Hα-helixtrans-63.4-36.3176.8-58.40000111.4L212 P214 Y238 L239 P240 A246L212-S242 PolarHBondContact O-OG 2.97Å; P214-S242 WeakPolarHBondContact CG-O 3.27Å; Y238-S242 WeakPolarHBondContact O-CB 3.14Å; Y238-S242 PolarHBondContact O-N 3.09Å; Y238-S242 PolarHBondContact O-OG 2.81Å; L239-S242 PolarHBondContact O-N 3.04Å; P240-S242 VanDerWaalsContact C-N 3.34Å; P240-S242 PolarHBondContact O-N 3.49Å; S242-A246 VanDerWaalsContact O-CB 3.24Å; S242-A246 WeakPolarHBondContact O-CB 3.33Å; S242-A246 PolarHBondContact O-N 2.95Å
243Y98.9Very high98.7Very high15 Ų1528.1 Ų28.16%0.05914%0.14CC..Hα-helixtrans-60.4-54.7172.9-173.8-77.2000111.4L239 P240 M241 Y245 A246 V247 V317 L320 Y321 I324 V347 Y350 V351L239-Y243 PolarHBondContact O-N 2.87Å; L239-Y243 VanDerWaalsContact O-N 3.13Å; P240-Y243 WeakPolarHBondContact O-CB 3.28Å; P240-Y243 PolarHBondContact O-N 3.32Å; M241-Y243 VanDerWaalsContact C-N 3.29Å; M241-Y243 PolarHBondContact O-N 3.33Å; Y243-Y245 VanDerWaalsContact C-N 3.29Å; Y243-Y245 PolarHBondContact O-N 3.06Å; Y243-A246 WeakPolarHBondContact O-CB 3.38Å; Y243-A246 PolarHBondContact O-N 2.84Å; Y243-A246 VanDerWaalsContact O-N 3.12Å; Y243-V247 HydrophobicContact CD1-CG2 4.39Å; Y243-V247 HydrophobicContact CE1-CG1 4.12Å; Y243-V247 HydrophobicContact CE1-CG2 4.12Å; Y243-V247 PolarHBondContact O-N 3.31Å; Y243-V317 HydrophobicContact CD2-CG1 4.27Å; Y243-V317 HydrophobicContact CE2-CG1 3.57Å; Y243-L320 HydrophobicContact CD2-CB 4.09Å; Y243-Y321 HydrophobicContact CE2-CD2 4.25Å; Y243-Y321 HydrophobicContact CE2-CG 4.34Å; Y243-I324 HydrophobicContact CD2-CD1 4.34Å; Y243-I324 HydrophobicContact CG-CD1 4.27Å; Y243-V347 HydrophobicContact CD1-CB 4.25Å; Y243-V347 HydrophobicContact CD1-CG1 3.69Å; Y243-V347 HydrophobicContact CD1-CG2 3.59Å; Y243-V347 HydrophobicContact CD2-CG1 4.28Å; Y243-V347 HydrophobicContact CE1-CG1 3.76Å; Y243-V347 HydrophobicContact CE1-CG2 4.32Å; Y243-V347 HydrophobicContact CE2-CG1 4.32Å; Y243-V347 HydrophobicContact CG-CG1 3.99Å; Y243-V347 HydrophobicContact CG-CG2 4.02Å; Y243-Y350 HydrophobicContact CE1-CD1 4.12Å; Y243-V351 HydrophobicContact CE1-CG2 4.08Å; Y243-V351 WeakPolarHBondContact OH-CG2 3.44Å
244C98.9Very high98.6Very high0 Ų027.9 Ų27.90%014%0.14CC..Hα-helixtrans-58.5-41.7179.7-67.70000111.8F196 W206 P240 M241 V247 R248 L249F196-C244 HydrophobicContact CE2-CB 3.84Å; F196-C244 HydrophobicContact CZ-CB 3.95Å; W206-C244 HydrophobicContact CH2-CB 4.38Å; P240-C244 PolarHBondContact O-N 3.18Å; P240-C244 PolarHBondContact O-SG 2.81Å; P240-C244 VanDerWaalsContact O-SG 3.41Å; M241-C244 PolarHBondContact O-N 2.6Å; C244-V247 PolarHBondContact O-N 3.24Å; C244-R248 WeakPolarHBondContact O-CA 3.41Å; C244-R248 PolarHBondContact O-N 3.32Å; C244-L249 HydrophobicContact CB-CB 4.21Å; C244-L249 PolarHBondContact O-N 3.19Å
245Y98.9Very high98.6Very high1 Ų132.7 Ų32.70%0.00417%0.171CC..Hα-helixtrans-61.9-46.2174.3179.7-93.9000112.1W206 L209 T211 L212 P214 M241 Y243 V247 R248 E305W206-Y245 HydrophobicContact CD2-CD2 4.5Å; W206-Y245 AromaticContact CE3-CD2 3.48Å; W206-Y245 HydrophobicContact CE3-CD2 3.48Å; W206-Y245 VanDerWaalsContact CE3-CD2 3.48Å; W206-Y245 HydrophobicContact CE3-CE2 4.13Å; W206-Y245 HydrophobicContact CE3-CG 4.42Å; W206-Y245 AromaticContact CZ3-CD2 3.68Å; W206-Y245 HydrophobicContact CZ3-CD2 3.68Å; W206-Y245 HydrophobicContact CZ3-CG 4.34Å; L209-Y245 HydrophobicContact CD1-CD2 3.74Å; L209-Y245 HydrophobicContact CD1-CE2 3.55Å; T211-Y245 WeakPolarHBondContact CA-OH 3.26Å; T211-Y245 WeakPolarHBondContact OG1-CE1 3.34Å; L212-Y245 HydrophobicContact CB-CD1 4.17Å; L212-Y245 HydrophobicContact CB-CG 4.05Å; L212-Y245 HydrophobicContact CD1-CG 4.31Å; L212-Y245 HydrophobicContact CG-CD2 4.22Å; L212-Y245 HydrophobicContact CG-CG 4.09Å; P214-Y245 HydrophobicContact CG-CD1 4.26Å; M241-Y245 WeakPolarHBondContact O-CB 3.31Å; M241-Y245 PolarHBondContact O-N 3.41Å; Y243-Y245 VanDerWaalsContact C-N 3.29Å; Y243-Y245 PolarHBondContact O-N 3.06Å; Y245-V247 PolarHBondContact O-N 3.04Å; Y245-R248 WeakPolarHBondContact O-CD 3.32Å; Y245-R248 PolarHBondContact O-N 3.41Å; Y245-R248 PolarHBondContact O-NH1 2.93Å; Y245-R248 PolarHBondContact OH-NH2 2.78Å; Y245-E305 HydrophobicContact CE1-CG 4.47Å; Y245-E305 WeakPolarHBondContact CE1-OE1 3.48Å; Y245-E305 VanDerWaalsContact OH-CD 3.24Å; Y245-E305 VanDerWaalsContact OH-CG 3.27Å; Y245-E305 WeakPolarHBondContact OH-CG 3.36Å; Y245-E305 PolarHBondContact OH-OE1 3.43Å
246A98.8Very high98.6Very high15 Ų1534 Ų3412%0.12418%0.178CC..Hα-helixtrans-59.4-34.3-177.800000113.2P214 S242 Y243 V317P214-A246 HydrophobicContact CB-CB 4.17Å; P214-A246 HydrophobicContact CG-CB 3.68Å; S242-A246 VanDerWaalsContact O-CB 3.24Å; S242-A246 WeakPolarHBondContact O-CB 3.33Å; S242-A246 PolarHBondContact O-N 2.95Å; Y243-A246 WeakPolarHBondContact O-CB 3.38Å; Y243-A246 PolarHBondContact O-N 2.84Å; Y243-A246 VanDerWaalsContact O-N 3.12Å; A246-V317 HydrophobicContact CB-CG2 3.56Å
247V98.8Very high98.6Very high41 Ų4133.6 Ų33.625%0.24818%0.176CC..THydrogen-bonded Turntrans-99.10.6179.4-52.90000113Y243 C244 Y245 L249 V317 Y350Y243-V247 HydrophobicContact CD1-CG2 4.39Å; Y243-V247 HydrophobicContact CE1-CG1 4.12Å; Y243-V247 HydrophobicContact CE1-CG2 4.12Å; Y243-V247 PolarHBondContact O-N 3.31Å; C244-V247 PolarHBondContact O-N 3.24Å; Y245-V247 PolarHBondContact O-N 3.04Å; V247-L249 VanDerWaalsContact C-N 3.27Å; V247-L249 HydrophobicContact CG2-CB 3.91Å; V247-L249 PolarHBondContact O-N 2.62Å; V247-V317 HydrophobicContact CG1-CG1 4.35Å; V247-V317 HydrophobicContact CG1-CG2 4.38Å; V247-Y350 HydrophobicContact CB-CE1 4.3Å; V247-Y350 HydrophobicContact CG2-CD1 4.49Å; V247-Y350 HydrophobicContact CG2-CE1 3.92Å
248R98.7Very high98.6Very high73 Ų7337.2 Ų37.228%0.27520%0.195SC..THydrogen-bonded Turntrans49.448.4-174.8-59.9-64.4-164.9-911.1111.7E207 C244 Y245 S250 E305E207-R248 IonicContact OE1-CZ 3.95Å; E207-R248 IonicContact OE1-NE 3.9Å; E207-R248 IonicContact OE1-NH2 2.93Å; E207-R248 PolarHBondContact OE1-NH2 3.28Å; C244-R248 WeakPolarHBondContact O-CA 3.41Å; C244-R248 PolarHBondContact O-N 3.32Å; Y245-R248 WeakPolarHBondContact O-CD 3.32Å; Y245-R248 PolarHBondContact O-N 3.41Å; Y245-R248 PolarHBondContact O-NH1 2.93Å; Y245-R248 PolarHBondContact OH-NH2 2.78Å; R248-S250 PolarHBondContact O-N 2.98Å; R248-S250 VanDerWaalsContact O-N 3.13Å; R248-E305 IonicContact CZ-OE1 3.09Å; R248-E305 IonicContact NH1-OE1 2.79Å; R248-E305 PolarHBondContact NH1-OE1 3.39Å; R248-E305 VanDerWaalsContact NH1-OE1 3.07Å; R248-E305 IonicContact NH2-OE1 3.49Å; R248-E305 PolarHBondContact NH2-OE1 2.86Å
249L98.8Very high98.6Very high5 Ų538 Ų383%0.02620%0.204CC..  trans-60.8116.8-178.3-168.6162.7000109.2V200 W206 C244 V247 L346 Y350V200-L249 HydrophobicContact CG1-CD2 4.2Å; W206-L249 VanDerWaalsContact CZ2-O 3.23Å; W206-L249 WeakPolarHBondContact CZ2-O 3.25Å; W206-L249 PolarHBondContact NE1-O 2.92Å; C244-L249 HydrophobicContact CB-CB 4.21Å; C244-L249 PolarHBondContact O-N 3.19Å; V247-L249 VanDerWaalsContact C-N 3.27Å; V247-L249 HydrophobicContact CG2-CB 3.91Å; V247-L249 PolarHBondContact O-N 2.62Å; L249-L346 HydrophobicContact CD1-CD1 4.49Å; L249-L346 HydrophobicContact CD1-CD2 4.26Å; L249-L346 HydrophobicContact CD1-CG 3.98Å; L249-L346 HydrophobicContact CD2-CD1 4.27Å; L249-L346 HydrophobicContact CD2-CD2 3.94Å; L249-L346 HydrophobicContact CD2-CG 4.23Å; L249-Y350 HydrophobicContact CD1-CD1 4.46Å; L249-Y350 HydrophobicContact CD1-CD2 3.82Å; L249-Y350 HydrophobicContact CD1-CG 3.76Å; L249-Y350 HydrophobicContact CG-CD2 4.03Å; L249-Y350 HydrophobicContact CG-CE2 4.41Å; L249-Y350 HydrophobicContact CG-CG 4.45Å
250S98.7Very high98.6Very high48 Ų4838 Ų3834%0.33620%0.204SC..  trans-136.9142.4179.9-73.90000110.5A199 V200 W206 R248A199-S250 PolarHBondContact O-OG 2.92Å; A199-S250 VanDerWaalsContact O-OG 3.1Å; V200-S250 CarbonylContact O-C 3.59Å; V200-S250 WeakPolarHBondContact O-CA 3.42Å; W206-S250 PolarHBondContact NE1-OG 3.33Å; R248-S250 PolarHBondContact O-N 2.98Å; R248-S250 VanDerWaalsContact O-N 3.13Å
251A98.3Very high98.6Very high5 Ų539.3 Ų39.34%0.04121%0.209CC..  trans-56.8144.5172.100000111.5I115 V200 N202 I257I115-A251 HydrophobicContact CD1-CB 4.12Å; I115-A251 HydrophobicContact CG1-CB 3.75Å; V200-A251 PolarHBondContact O-N 2.78Å; N202-A251 HydrophobicContact CB-CB 4.19Å; N202-A251 WeakPolarHBondContact CB-O 3.47Å; N202-A251 PolarHBondContact ND2-O 3.33Å; A251-I257 HydrophobicContact CB-CD1 3.56Å
252E97.2Very high98.6Very high177 Ų17745.2 Ų45.283%0.82724%0.236SC*.  trans-62.5141.6167.6-65.9-176.5171.900110.1D254 I257E252-D254 PolarHBondContact O-N 3.27Å; E252-D254 VanDerWaalsContact O-N 3.15Å; E252-I257 WeakPolarHBondContact O-CD1 3.41Å
253E97.4Very high98.6Very high116 Ų11645.9 Ų45.954%0.54224%0.239SC..  trans-70.3111.8-178.7-62.8-169.5169.400111.1R261E253-R261 VanDerWaalsContact CD-NH1 3.29Å; E253-R261 IonicContact OE1-CZ 3.53Å; E253-R261 IonicContact OE1-NH1 3.81Å; E253-R261 PolarHBondContact OE1-NH1 2.95Å; E253-R261 IonicContact OE1-NH2 3.39Å; E253-R261 PolarHBondContact OE1-NH2 3.15Å; E253-R261 IonicContact OE2-NH1 2.71Å
254D98.1Very high98.6Very high36 Ų3645.1 Ų45.119%0.19324%0.236CC..  trans-116.5171.2173.177.221.3000111.4H114 E252 L256 I257 L258H114-D254 IonicContact CE1-OD2 3.1Å; H114-D254 PolarHBondContact CE1-OD2 3.04Å; H114-D254 IonicContact NE2-OD2 2.69Å; H114-D254 PolarHBondContact NE2-OD2 3.4Å; E252-D254 PolarHBondContact O-N 3.27Å; E252-D254 VanDerWaalsContact O-N 3.15Å; D254-L256 PolarHBondContact O-N 3.1Å; D254-L256 WeakPolarHBondContact OD1-CA 3.32Å; D254-L256 WeakPolarHBondContact OD1-CB 3.44Å; D254-L256 PolarHBondContact OD1-N 3.36Å; D254-I257 PolarHBondContact O-N 3.14Å; D254-I257 VanDerWaalsContact O-N 3.13Å; D254-I257 PolarHBondContact OD1-N 2.97Å; D254-L258 WeakPolarHBondContact O-CG 3.41Å; D254-L258 PolarHBondContact O-N 3.21Å
255P98.6Very high98.6Very high108 Ų10845.5 Ų45.570%0.70124%0.238SC*.Hα-helixtrans-57.2-32.3-177.4-27.936.6000114.3S259P255-S259 WeakPolarHBondContact O-CB 3.43Å; P255-S259 PolarHBondContact O-N 2.71Å
256L98.7Very high98.5Very high31 Ų3149.5 Ų49.516%0.16226%0.262CS..Hα-helixtrans-68.2-46.3177.8170.663.4000110.2R163 I164 D254 L258 S259 L260R163-L256 HydrophobicContact CB-CD1 3.9Å; I164-L256 HydrophobicContact CB-CD2 4.49Å; I164-L256 HydrophobicContact CG1-CD2 3.92Å; D254-L256 PolarHBondContact O-N 3.1Å; D254-L256 WeakPolarHBondContact OD1-CA 3.32Å; D254-L256 WeakPolarHBondContact OD1-CB 3.44Å; D254-L256 PolarHBondContact OD1-N 3.36Å; L256-L258 VanDerWaalsContact C-N 3.34Å; L256-L258 PolarHBondContact O-N 2.73Å; L256-S259 WeakPolarHBondContact O-CB 3.43Å; L256-S259 PolarHBondContact O-N 3.5Å; L256-L260 HydrophobicContact CD1-CD1 4.07Å; L256-L260 HydrophobicContact CD1-CG 4.03Å; L256-L260 HydrophobicContact CG-CD1 4Å; L256-L260 HydrophobicContact CG-CG 4.4Å; L256-L260 WeakPolarHBondContact O-CB 3.49Å; L256-L260 WeakPolarHBondContact O-CG 3.46Å; L256-L260 PolarHBondContact O-N 2.88Å
257I98.7Very high98.4Very high0 Ų052 Ų520%027%0.271CS..Hα-helixtrans-60.5-44.6177.9-72.7163.2000111L201 N202 V203 A251 E252 D254 S259 L260 R261L201-I257 HydrophobicContact CD1-CD1 4.49Å; L201-I257 HydrophobicContact CD1-CG1 4.29Å; L201-I257 HydrophobicContact CG-CG1 4.48Å; L201-I257 WeakPolarHBondContact O-CD1 3.28Å; N202-I257 HydrophobicContact CB-CG2 4.4Å; V203-I257 HydrophobicContact CG1-CB 4.35Å; V203-I257 HydrophobicContact CG1-CG1 4.46Å; V203-I257 HydrophobicContact CG1-CG2 3.88Å; A251-I257 HydrophobicContact CB-CD1 3.56Å; E252-I257 WeakPolarHBondContact O-CD1 3.41Å; D254-I257 PolarHBondContact O-N 3.14Å; D254-I257 VanDerWaalsContact O-N 3.13Å; D254-I257 PolarHBondContact OD1-N 2.97Å; I257-S259 VanDerWaalsContact C-N 3.31Å; I257-S259 PolarHBondContact O-N 3.46Å; I257-L260 PolarHBondContact O-N 3Å; I257-R261 WeakPolarHBondContact O-CG 3.34Å; I257-R261 PolarHBondContact O-N 3.21Å; I257-R261 VanDerWaalsContact O-N 3.09Å
258L98.6Very high98.3Very high83 Ų8354.7 Ų54.744%0.43528%0.284SS..Hα-helixtrans-61.9-39.5176.8-65.5177.8000112D254 L256D254-L258 WeakPolarHBondContact O-CG 3.41Å; D254-L258 PolarHBondContact O-N 3.21Å; L256-L258 VanDerWaalsContact C-N 3.34Å; L256-L258 PolarHBondContact O-N 2.73Å
259S98.8Very high98.3Very high42 Ų4252.8 Ų52.829%0.29428%0.278SS..Hα-helixtrans-65.9-47.6175.6-158.90000111.5P255 L256 I257 R261 Q262 E263P255-S259 WeakPolarHBondContact O-CB 3.43Å; P255-S259 PolarHBondContact O-N 2.71Å; L256-S259 WeakPolarHBondContact O-CB 3.43Å; L256-S259 PolarHBondContact O-N 3.5Å; I257-S259 VanDerWaalsContact C-N 3.31Å; I257-S259 PolarHBondContact O-N 3.46Å; S259-R261 VanDerWaalsContact C-N 3.27Å; S259-R261 PolarHBondContact O-N 3.42Å; S259-Q262 WeakPolarHBondContact O-CA 3.44Å; S259-Q262 WeakPolarHBondContact O-CB 3.43Å; S259-Q262 PolarHBondContact O-N 3Å; S259-E263 VanDerWaalsContact CB-OE1 3.28Å; S259-E263 WeakPolarHBondContact CB-OE1 3.47Å; S259-E263 VanDerWaalsContact O-CG 3.29Å; S259-E263 WeakPolarHBondContact O-CG 3.35Å; S259-E263 PolarHBondContact O-N 2.91Å; S259-E263 PolarHBondContact OG-OE1 3.1Å
260L98.9Very high98.3Very high0 Ų056.9 Ų56.90%031%0.313CS..Hα-helixtrans-58.3-36.5178.8-75.3172.7000112.8Y159 T160 R163 L201 V203 L256 I257 Q262 E263 L264Y159-L260 HydrophobicContact CD1-CD2 4.34Å; Y159-L260 HydrophobicContact CE1-CD2 4.01Å; T160-L260 HydrophobicContact CG2-CD1 4.12Å; R163-L260 HydrophobicContact CB-CD2 4Å; R163-L260 HydrophobicContact CG-CD2 3.92Å; L201-L260 HydrophobicContact CD2-CD1 3.9Å; V203-L260 HydrophobicContact CB-CB 4.5Å; V203-L260 HydrophobicContact CG1-CB 3.76Å; V203-L260 HydrophobicContact CG1-CD1 4.25Å; L256-L260 HydrophobicContact CD1-CD1 4.07Å; L256-L260 HydrophobicContact CD1-CG 4.03Å; L256-L260 HydrophobicContact CG-CD1 4Å; L256-L260 HydrophobicContact CG-CG 4.4Å; L256-L260 WeakPolarHBondContact O-CB 3.49Å; L256-L260 WeakPolarHBondContact O-CG 3.46Å; L256-L260 PolarHBondContact O-N 2.88Å; I257-L260 PolarHBondContact O-N 3Å; L260-Q262 PolarHBondContact O-N 3.38Å; L260-E263 PolarHBondContact O-N 3.4Å; L260-E263 VanDerWaalsContact O-N 3.11Å; L260-L264 HydrophobicContact CB-CD1 4.24Å; L260-L264 HydrophobicContact CD2-CD1 4.44Å; L260-L264 HydrophobicContact CD2-CG 4.43Å; L260-L264 WeakPolarHBondContact O-CB 3.04Å; L260-L264 WeakPolarHBondContact O-CG 3.21Å; L260-L264 PolarHBondContact O-N 2.92Å
261R98.8Very high98.2Very high27 Ų2758.4 Ų58.410%0.10232%0.324CS..Hα-helixtrans-60-27.7173.7-72.3173.5175.4179.5-1.3113N202 V203 E253 I257 S259 F265 F269N202-R261 VanDerWaalsContact CG-NH2 3.28Å; N202-R261 VanDerWaalsContact O-CZ 3.25Å; N202-R261 PolarHBondContact O-NE 2.88Å; N202-R261 PolarHBondContact O-NH2 3.44Å; N202-R261 PolarHBondContact OD1-NH2 3.23Å; V203-R261 HydrophobicContact CB-CG 4.2Å; V203-R261 HydrophobicContact CG1-CG 4.24Å; E253-R261 VanDerWaalsContact CD-NH1 3.29Å; E253-R261 IonicContact OE1-CZ 3.53Å; E253-R261 IonicContact OE1-NH1 3.81Å; E253-R261 PolarHBondContact OE1-NH1 2.95Å; E253-R261 IonicContact OE1-NH2 3.39Å; E253-R261 PolarHBondContact OE1-NH2 3.15Å; E253-R261 IonicContact OE2-NH1 2.71Å; I257-R261 WeakPolarHBondContact O-CG 3.34Å; I257-R261 PolarHBondContact O-N 3.21Å; I257-R261 VanDerWaalsContact O-N 3.09Å; S259-R261 VanDerWaalsContact C-N 3.27Å; S259-R261 PolarHBondContact O-N 3.42Å; R261-F265 WeakPolarHBondContact O-CD2 3.2Å; R261-F269 HydrophobicContact CB-CB 4.36Å; R261-F269 HydrophobicContact CB-CD1 4.1Å; R261-F269 HydrophobicContact CB-CD2 3.81Å; R261-F269 HydrophobicContact CB-CE1 4.37Å; R261-F269 HydrophobicContact CB-CE2 4.1Å; R261-F269 HydrophobicContact CB-CG 3.81Å; R261-F269 HydrophobicContact CB-CZ 4.37Å; R261-F269 VanDerWaalsContact CD-CE1 3.47Å; R261-F269 HydrophobicContact CG-CD1 4.14Å; R261-F269 HydrophobicContact CG-CD2 3.93Å; R261-F269 HydrophobicContact CG-CE1 3.89Å; R261-F269 HydrophobicContact CG-CE2 3.67Å; R261-F269 HydrophobicContact CG-CG 4.16Å; R261-F269 HydrophobicContact CG-CZ 3.65Å
262Q98.6Very high98.2Very high126 Ų12658.8 Ų58.859%0.58933%0.325SS*.Hα-helixtrans-91.1-20.5175.7-55.4-55.5-46.400112.8S259 L260S259-Q262 WeakPolarHBondContact O-CA 3.44Å; S259-Q262 WeakPolarHBondContact O-CB 3.43Å; S259-Q262 PolarHBondContact O-N 3Å; L260-Q262 PolarHBondContact O-N 3.38Å
263E98.8Very high98.3Very high14 Ų1454.8 Ų54.87%0.06531%0.309CS..Hα-helixtrans-90.5-36.9-175.5-67.3166.8-145.500113Y159 R163 P169 R178 H182 S259 L260Y159-E263 HydrophobicContact CE1-CB 4.08Å; Y159-E263 WeakPolarHBondContact CE1-OE2 3.12Å; Y159-E263 VanDerWaalsContact CZ-OE2 3.24Å; Y159-E263 PolarHBondContact OH-OE2 2.9Å; R163-E263 IonicContact CZ-OE1 2.98Å; R163-E263 IonicContact CZ-OE2 3.29Å; R163-E263 IonicContact NE-OE1 3.3Å; R163-E263 PolarHBondContact NE-OE1 3.28Å; R163-E263 IonicContact NE-OE2 3.03Å; R163-E263 PolarHBondContact NE-OE2 2.78Å; R163-E263 IonicContact NH2-OE1 2.93Å; R163-E263 PolarHBondContact NH2-OE1 2.83Å; R163-E263 VanDerWaalsContact NH2-OE1 3.09Å; R163-E263 IonicContact NH2-OE2 2.7Å; P169-E263 HydrophobicContact CB-CG 4.49Å; R178-E263 WeakPolarHBondContact CD-O 3.46Å; H182-E263 PolarHBondContact NE2-O 3.42Å; S259-E263 VanDerWaalsContact CB-OE1 3.28Å; S259-E263 WeakPolarHBondContact CB-OE1 3.47Å; S259-E263 VanDerWaalsContact O-CG 3.29Å; S259-E263 WeakPolarHBondContact O-CG 3.35Å; S259-E263 PolarHBondContact O-N 2.91Å; S259-E263 PolarHBondContact OG-OE1 3.1Å; L260-E263 PolarHBondContact O-N 3.4Å; L260-E263 VanDerWaalsContact O-N 3.11Å
264L98.9Very high98.4Very high0 Ų051.2 Ų51.20%029%0.291CS..SBendtrans-84.4-15.9-167.4-68.3176.5000115Y159 L181 A187 L198 V203 L260Y159-L264 HydrophobicContact CD1-CD2 3.69Å; Y159-L264 HydrophobicContact CE1-CD2 4.14Å; L181-L264 HydrophobicContact CD2-CD2 3.97Å; A187-L264 HydrophobicContact CB-CB 4.01Å; A187-L264 WeakPolarHBondContact CB-O 3.08Å; A187-L264 PolarHBondContact N-O 3.06Å; L198-L264 HydrophobicContact CD2-CD1 4.32Å; V203-L264 HydrophobicContact CB-CD1 4.41Å; V203-L264 HydrophobicContact CG2-CD1 3.89Å; L260-L264 HydrophobicContact CB-CD1 4.24Å; L260-L264 HydrophobicContact CD2-CD1 4.44Å; L260-L264 HydrophobicContact CD2-CG 4.43Å; L260-L264 WeakPolarHBondContact O-CB 3.04Å; L260-L264 WeakPolarHBondContact O-CG 3.21Å; L260-L264 PolarHBondContact O-N 2.92Å
265F98.8Very high98.3Very high8 Ų852.6 Ų52.64%0.03530%0.303CS..  trans-118.2148.1-170.2-57.6-81.2000111.5H182 A187 V188 V203 Y204 R261 F269 I272 W274H182-F265 PolarHBondContact CE1-O 3.18Å; H182-F265 PolarHBondContact NE2-O 2.56Å; A187-F265 HydrophobicContact CB-CD1 4.12Å; A187-F265 HydrophobicContact CB-CE1 3.75Å; A187-F265 HydrophobicContact CB-CZ 4.14Å; V188-F265 HydrophobicContact CG1-CD1 3.69Å; V188-F265 HydrophobicContact CG1-CE1 3.91Å; V203-F265 WeakPolarHBondContact O-CE2 3.46Å; V203-F265 WeakPolarHBondContact O-CZ 3.38Å; Y204-F265 HydrophobicContact CD2-CE1 4.17Å; Y204-F265 HydrophobicContact CD2-CZ 4.2Å; R261-F265 WeakPolarHBondContact O-CD2 3.2Å; F265-F269 AromaticContact CD2-CD2 3.71Å; F265-F269 HydrophobicContact CD2-CD2 3.71Å; F265-F269 HydrophobicContact CD2-CE2 4.31Å; F265-F269 AromaticContact CE2-CD2 3.61Å; F265-F269 HydrophobicContact CE2-CD2 3.61Å; F265-F269 AromaticContact CE2-CE2 3.73Å; F265-F269 HydrophobicContact CE2-CE2 3.73Å; F265-F269 HydrophobicContact CZ-CD2 4.36Å; F265-F269 HydrophobicContact CZ-CE2 4.21Å; F265-I272 HydrophobicContact CB-CD1 4.19Å; F265-I272 HydrophobicContact CD1-CD1 3.67Å; F265-I272 HydrophobicContact CD2-CD1 4.39Å; F265-I272 HydrophobicContact CE1-CD1 4.1Å; F265-I272 HydrophobicContact CG-CD1 3.81Å; F265-W274 AromaticContact CE1-CH2 3.97Å; F265-W274 HydrophobicContact CE1-CH2 3.97Å; F265-W274 HydrophobicContact CE1-CZ3 4.31Å; F265-W274 AromaticContact CZ-CH2 3.91Å; F265-W274 HydrophobicContact CZ-CH2 3.91Å
266V98.3Very high98.3Very high84 Ų8450.1 Ų50.151%0.50929%0.292SS..SBendtrans-80.2-41.9177176.80000110.6H182H182-V266 HydrophobicContact CB-CG2 3.94Å
267Q96.1Very high98.3Very high68 Ų6849.9 Ų49.932%0.31829%0.29SS..SBendtrans-84.7160.2174.762.9-89.329.400112F269 I272Q267-F269 PolarHBondContact O-N 2.73Å; Q267-I272 HydrophobicContact CG-CD1 4.15Å; Q267-I272 HydrophobicContact CG-CG1 3.53Å
268D97.5Very high98.3Very high97 Ų9752.3 Ų52.352%0.51930%0.299SS..  trans-56.3123.3170179.2-5.6000110.1A270 S271D268-A270 PolarHBondContact O-N 3.3Å; D268-A270 PolarHBondContact OD1-N 3.41Å; D268-A270 VanDerWaalsContact OD1-N 3.07Å; D268-S271 PolarHBondContact O-N 2.93Å; D268-S271 PolarHBondContact O-OG 3.03Å
269F98.3Very high98.3Very high33 Ų3353.4 Ų53.415%0.14531%0.305CS..G310 helixtrans-50.9-41.9-178.2-176.1-98.2000113.2V203 R261 F265 Q267 S271 I272 W274V203-F269 VanDerWaalsContact O-CE2 3.29Å; V203-F269 WeakPolarHBondContact O-CE2 3.36Å; R261-F269 HydrophobicContact CB-CB 4.36Å; R261-F269 HydrophobicContact CB-CD1 4.1Å; R261-F269 HydrophobicContact CB-CD2 3.81Å; R261-F269 HydrophobicContact CB-CE1 4.37Å; R261-F269 HydrophobicContact CB-CE2 4.1Å; R261-F269 HydrophobicContact CB-CG 3.81Å; R261-F269 HydrophobicContact CB-CZ 4.37Å; R261-F269 VanDerWaalsContact CD-CE1 3.47Å; R261-F269 HydrophobicContact CG-CD1 4.14Å; R261-F269 HydrophobicContact CG-CD2 3.93Å; R261-F269 HydrophobicContact CG-CE1 3.89Å; R261-F269 HydrophobicContact CG-CE2 3.67Å; R261-F269 HydrophobicContact CG-CG 4.16Å; R261-F269 HydrophobicContact CG-CZ 3.65Å; F265-F269 AromaticContact CD2-CD2 3.71Å; F265-F269 HydrophobicContact CD2-CD2 3.71Å; F265-F269 HydrophobicContact CD2-CE2 4.31Å; F265-F269 AromaticContact CE2-CD2 3.61Å; F265-F269 HydrophobicContact CE2-CD2 3.61Å; F265-F269 AromaticContact CE2-CE2 3.73Å; F265-F269 HydrophobicContact CE2-CE2 3.73Å; F265-F269 HydrophobicContact CZ-CD2 4.36Å; F265-F269 HydrophobicContact CZ-CE2 4.21Å; Q267-F269 PolarHBondContact O-N 2.73Å; F269-S271 PolarHBondContact O-N 2.94Å; F269-I272 HydrophobicContact CD2-CD1 4.13Å; F269-I272 PolarHBondContact O-N 3.21Å; F269-W274 HydrophobicContact CD2-CH2 4.31Å; F269-W274 HydrophobicContact CD2-CZ2 4.03Å; F269-W274 AromaticContact CE2-CH2 3.76Å; F269-W274 HydrophobicContact CE2-CH2 3.76Å; F269-W274 AromaticContact CE2-CZ2 3.47Å; F269-W274 HydrophobicContact CE2-CZ2 3.47Å; F269-W274 VanDerWaalsContact CE2-CZ2 3.47Å; F269-W274 HydrophobicContact CZ-CH2 4.42Å; F269-W274 AromaticContact CZ-CZ2 3.77Å; F269-W274 HydrophobicContact CZ-CZ2 3.77Å
270A97.6Very high98.3Very high92 Ų9254.2 Ų54.276%0.7631%0.306SS*.G310 helixtrans-69-19.6-177.500000112.9D268D268-A270 PolarHBondContact O-N 3.3Å; D268-A270 PolarHBondContact OD1-N 3.41Å; D268-A270 VanDerWaalsContact OD1-N 3.07Å
271S98Very high98.3Very high80 Ų8055.4 Ų55.456%0.55931%0.314SS*.G310 helixtrans-94.3-4.9-17875.80000114.1D268 F269 N273D268-S271 PolarHBondContact O-N 2.93Å; D268-S271 PolarHBondContact O-OG 3.03Å; F269-S271 PolarHBondContact O-N 2.94Å; S271-N273 PolarHBondContact O-N 3.06Å
272I98.7Very high98.2Very high12 Ų1254.8 Ų54.86%0.06231%0.314CS..  trans-65.9120.4-175.8-62.6172.8000110.4V188 F265 Q267 F269 W274 Q277V188-I272 HydrophobicContact CG1-CD1 4.04Å; V188-I272 HydrophobicContact CG1-CG2 4.01Å; F265-I272 HydrophobicContact CB-CD1 4.19Å; F265-I272 HydrophobicContact CD1-CD1 3.67Å; F265-I272 HydrophobicContact CD2-CD1 4.39Å; F265-I272 HydrophobicContact CE1-CD1 4.1Å; F265-I272 HydrophobicContact CG-CD1 3.81Å; Q267-I272 HydrophobicContact CG-CD1 4.15Å; Q267-I272 HydrophobicContact CG-CG1 3.53Å; F269-I272 HydrophobicContact CD2-CD1 4.13Å; F269-I272 PolarHBondContact O-N 3.21Å; I272-W274 HydrophobicContact CB-CD2 4.22Å; I272-W274 HydrophobicContact CB-CH2 4.21Å; I272-W274 HydrophobicContact CB-CZ2 3.87Å; I272-W274 HydrophobicContact CD1-CH2 3.55Å; I272-W274 HydrophobicContact CD1-CZ2 3.74Å; I272-W274 HydrophobicContact CD1-CZ3 4.27Å; I272-W274 HydrophobicContact CG1-CH2 4.47Å; I272-W274 HydrophobicContact CG1-CZ2 4.36Å; I272-W274 HydrophobicContact CG2-CD2 3.64Å; I272-W274 HydrophobicContact CG2-CE3 3.6Å; I272-W274 HydrophobicContact CG2-CG 4.29Å; I272-W274 HydrophobicContact CG2-CH2 3.91Å; I272-W274 HydrophobicContact CG2-CZ2 3.94Å; I272-W274 HydrophobicContact CG2-CZ3 3.73Å; I272-W274 PolarHBondContact O-N 2.99Å; I272-Q277 HydrophobicContact CG2-CG 4.03Å
273N98.3Very high98.2Very high94 Ų9453.3 Ų53.350%0.50332%0.323SS..  trans-75.687.9167.5-180-3.2000110S271 S275 A276 Q277S271-N273 PolarHBondContact O-N 3.06Å; N273-S275 PolarHBondContact O-N 3.16Å; N273-S275 PolarHBondContact OD1-N 3.13Å; N273-S275 PolarHBondContact OD1-OG 3.22Å; N273-A276 HydrophobicContact CB-CB 4.32Å; N273-A276 PolarHBondContact O-N 3.25Å; N273-Q277 WeakPolarHBondContact O-CG 3.37Å; N273-Q277 PolarHBondContact O-NE2 3.42Å
274W98.6Very high98.1Very high41 Ų4155.8 Ų55.816%0.15534%0.342CS..G310 helixtrans-55.8-44.5-175.6-67.1114.5000113.5Y204 S205 G208 F265 F269 I272 A276 Q277Y204-W274 HydrophobicContact CD1-CE3 4.25Å; Y204-W274 HydrophobicContact CD1-CZ3 4.02Å; Y204-W274 HydrophobicContact CD2-CE3 4.43Å; Y204-W274 HydrophobicContact CD2-CH2 4.21Å; Y204-W274 AromaticContact CD2-CZ3 3.54Å; Y204-W274 HydrophobicContact CD2-CZ3 3.54Å; Y204-W274 AromaticContact CE1-CE3 3.99Å; Y204-W274 HydrophobicContact CE1-CE3 3.99Å; Y204-W274 HydrophobicContact CE1-CZ3 4.04Å; Y204-W274 HydrophobicContact CE2-CE3 4.22Å; Y204-W274 AromaticContact CE2-CZ3 3.59Å; Y204-W274 HydrophobicContact CE2-CZ3 3.59Å; Y204-W274 HydrophobicContact CG-CE3 4.42Å; Y204-W274 HydrophobicContact CG-CH2 4.31Å; Y204-W274 AromaticContact CG-CZ3 3.74Å; Y204-W274 HydrophobicContact CG-CZ3 3.74Å; Y204-W274 AromaticContact CZ-CE3 3.95Å; Y204-W274 AromaticContact CZ-CZ3 3.81Å; S205-W274 VanDerWaalsContact CB-CD1 3.49Å; G208-W274 WeakPolarHBondContact CA-O 3.28Å; F265-W274 AromaticContact CE1-CH2 3.97Å; F265-W274 HydrophobicContact CE1-CH2 3.97Å; F265-W274 HydrophobicContact CE1-CZ3 4.31Å; F265-W274 AromaticContact CZ-CH2 3.91Å; F265-W274 HydrophobicContact CZ-CH2 3.91Å; F269-W274 HydrophobicContact CD2-CH2 4.31Å; F269-W274 HydrophobicContact CD2-CZ2 4.03Å; F269-W274 AromaticContact CE2-CH2 3.76Å; F269-W274 HydrophobicContact CE2-CH2 3.76Å; F269-W274 AromaticContact CE2-CZ2 3.47Å; F269-W274 HydrophobicContact CE2-CZ2 3.47Å; F269-W274 VanDerWaalsContact CE2-CZ2 3.47Å; F269-W274 HydrophobicContact CZ-CH2 4.42Å; F269-W274 AromaticContact CZ-CZ2 3.77Å; F269-W274 HydrophobicContact CZ-CZ2 3.77Å; I272-W274 HydrophobicContact CB-CD2 4.22Å; I272-W274 HydrophobicContact CB-CH2 4.21Å; I272-W274 HydrophobicContact CB-CZ2 3.87Å; I272-W274 HydrophobicContact CD1-CH2 3.55Å; I272-W274 HydrophobicContact CD1-CZ2 3.74Å; I272-W274 HydrophobicContact CD1-CZ3 4.27Å; I272-W274 HydrophobicContact CG1-CH2 4.47Å; I272-W274 HydrophobicContact CG1-CZ2 4.36Å; I272-W274 HydrophobicContact CG2-CD2 3.64Å; I272-W274 HydrophobicContact CG2-CE3 3.6Å; I272-W274 HydrophobicContact CG2-CG 4.29Å; I272-W274 HydrophobicContact CG2-CH2 3.91Å; I272-W274 HydrophobicContact CG2-CZ2 3.94Å; I272-W274 HydrophobicContact CG2-CZ3 3.73Å; I272-W274 PolarHBondContact O-N 2.99Å; W274-A276 PolarHBondContact O-N 3.33Å; W274-A276 VanDerWaalsContact O-N 3.15Å; W274-Q277 HydrophobicContact CE3-CG 4.43Å; W274-Q277 WeakPolarHBondContact O-CA 3.27Å; W274-Q277 WeakPolarHBondContact O-CB 3.46Å; W274-Q277 PolarHBondContact O-N 2.86Å
275S97.5Very high98Very high64 Ų6456.4 Ų56.445%0.44835%0.345SS..G310 helixtrans-57.4-34.3-178.969.80000113.4N273 Q277 R278N273-S275 PolarHBondContact O-N 3.16Å; N273-S275 PolarHBondContact OD1-N 3.13Å; N273-S275 PolarHBondContact OD1-OG 3.22Å; S275-Q277 PolarHBondContact O-N 3.23Å; S275-R278 WeakPolarHBondContact O-CG 3.31Å; S275-R278 PolarHBondContact O-N 3.23Å
276A98.2Very high98Very high57 Ų5759.2 Ų59.247%0.47136%0.36SS..G310 helixtrans-71.9-16.3176.400000113.1N273 W274N273-A276 HydrophobicContact CB-CB 4.32Å; N273-A276 PolarHBondContact O-N 3.25Å; W274-A276 PolarHBondContact O-N 3.33Å; W274-A276 VanDerWaalsContact O-N 3.15Å
277Q98.7Very high98Very high25 Ų2558.6 Ų58.612%0.11735%0.349CS..G310 helixtrans-86.6-9.2-179.4-45.6-40.3-54.500112.8V188 K195 Y204 G208 I272 N273 W274 S275 N279 N280V188-Q277 HydrophobicContact CB-CG 4.25Å; V188-Q277 HydrophobicContact CG1-CG 4.25Å; K195-Q277 PolarHBondContact NZ-O 2.74Å; Y204-Q277 VanDerWaalsContact OH-CB 3.22Å; Y204-Q277 WeakPolarHBondContact OH-CB 3.36Å; G208-Q277 CarbonylContact O-C 3.51Å; I272-Q277 HydrophobicContact CG2-CG 4.03Å; N273-Q277 WeakPolarHBondContact O-CG 3.37Å; N273-Q277 PolarHBondContact O-NE2 3.42Å; W274-Q277 HydrophobicContact CE3-CG 4.43Å; W274-Q277 WeakPolarHBondContact O-CA 3.27Å; W274-Q277 WeakPolarHBondContact O-CB 3.46Å; W274-Q277 PolarHBondContact O-N 2.86Å; S275-Q277 PolarHBondContact O-N 3.23Å; Q277-N279 VanDerWaalsContact C-N 3.29Å; Q277-N279 PolarHBondContact O-N 2.71Å; Q277-N280 HydrophobicContact CB-CB 4.39Å; Q277-N280 WeakPolarHBondContact O-CB 3.21Å; Q277-N280 PolarHBondContact O-N 2.85Å; Q277-N280 PolarHBondContact OE1-ND2 3.47Å
278R98.4Very high98.1Very high52 Ų5256.7 Ų56.720%0.19634%0.342CS..THydrogen-bonded Turntrans-51.9-45.5-176.6-69.2177.2179.5168.4-4.6113.2K195 E207 G208 N210 S275K195-R278 PolarHBondContact NZ-O 3.35Å; E207-R278 PolarHBondContact O-NE 2.89Å; E207-R278 PolarHBondContact O-NH2 3.22Å; E207-R278 IonicContact OE2-NH2 3.31Å; E207-R278 PolarHBondContact OE2-NH2 3.47Å; E207-R278 VanDerWaalsContact OE2-NH2 3.1Å; G208-R278 WeakPolarHBondContact O-CA 3.25Å; G208-R278 PolarHBondContact O-N 3.01Å; N210-R278 PolarHBondContact ND2-O 2.89Å; S275-R278 WeakPolarHBondContact O-CG 3.31Å; S275-R278 PolarHBondContact O-N 3.23Å
279N98.3Very high98.1Very high106 Ų10656 Ų5657%0.56734%0.343SS*.THydrogen-bonded Turntrans-102.78.7178.4-61.4-27.4000113.3N210 Q277 V281N210-N279 PolarHBondContact ND2-OD1 3.47Å; Q277-N279 VanDerWaalsContact C-N 3.29Å; Q277-N279 PolarHBondContact O-N 2.71Å; N279-V281 PolarHBondContact O-N 3.48Å
280N98.6Very high98.1Very high58 Ų5856.2 Ų56.231%0.3134%0.344SS..  trans-79.3110.3173.1-174.67000108.8K195 Q277K195-N280 WeakPolarHBondContact CE-O 3.22Å; K195-N280 PolarHBondContact NZ-O 2.89Å; Q277-N280 HydrophobicContact CB-CB 4.39Å; Q277-N280 WeakPolarHBondContact O-CB 3.21Å; Q277-N280 PolarHBondContact O-N 2.85Å; Q277-N280 PolarHBondContact OE1-ND2 3.47Å
281V98.7Very high98.1Very high26 Ų2653.1 Ų53.116%0.15832%0.317CS..  trans-135130.7172.6-179.70000107.5G189 P191 N279 D285 L286 E520G189-V281 CarbonylContact O-C 3.46Å; G189-V281 WeakPolarHBondContact O-CA 3.39Å; P191-V281 HydrophobicContact CB-CG1 4.3Å; P191-V281 HydrophobicContact CG-CG1 3.97Å; N279-V281 PolarHBondContact O-N 3.48Å; V281-D285 HydrophobicContact CG1-CB 4.4Å; V281-L286 HydrophobicContact CG1-CD1 4.21Å; V281-E520 HydrophobicContact CG1-CB 4.39Å; V281-E520 HydrophobicContact CG2-CG 4.16Å
282A98.3Very high98.2Very high14 Ų1455 Ų5512%0.11633%0.325CS..  trans-62.8138.1-178.200000110.7V152 G189 C284 D285 L286V152-A282 HydrophobicContact CB-CB 4.19Å; V152-A282 HydrophobicContact CG2-CB 3.53Å; G189-A282 PolarHBondContact O-N 2.89Å; A282-C284 PolarHBondContact O-N 2.99Å; A282-C284 VanDerWaalsContact O-N 3.14Å; A282-D285 PolarHBondContact O-N 2.8Å; A282-L286 PolarHBondContact O-N 3.49Å
283A97.7Very high98.1Very high94 Ų9458.7 Ų58.778%0.77735%0.345SS*.THydrogen-bonded Turntrans-61.5-26.1-176.800000113.3D285 L286A283-D285 VanDerWaalsContact C-N 3.25Å; A283-D285 PolarHBondContact O-N 3.25Å; A283-L286 PolarHBondContact O-N 2.79Å
284C96.5Very high98.1Very high67 Ų6754.6 Ų54.645%0.45332%0.323SS..THydrogen-bonded Turntrans-72.7-15176.856.90000114.1A282A282-C284 PolarHBondContact O-N 2.99Å; A282-C284 VanDerWaalsContact O-N 3.14Å
285D97.9Very high98.1Very high13 Ų1354.8 Ų54.87%0.0733%0.33CS..THydrogen-bonded Turntrans-100.4-14.3176.9-70.9-83.5000112.7T151 V152 F153 P191 V281 A282 A283 Y287 V521T151-D285 WeakPolarHBondContact CB-OD1 3.2Å; T151-D285 PolarHBondContact OG1-OD1 3.26Å; V152-D285 VanDerWaalsContact CB-OD2 3.31Å; V152-D285 WeakPolarHBondContact CB-OD2 3.2Å; V152-D285 PolarHBondContact N-OD2 2.98Å; F153-D285 WeakPolarHBondContact CB-OD1 3.2Å; F153-D285 PolarHBondContact N-OD1 3.45Å; F153-D285 VanDerWaalsContact N-OD1 3.16Å; P191-D285 HydrophobicContact CG-CB 3.47Å; P191-D285 VanDerWaalsContact CG-CB 3.47Å; V281-D285 HydrophobicContact CG1-CB 4.4Å; A282-D285 PolarHBondContact O-N 2.8Å; A283-D285 VanDerWaalsContact C-N 3.25Å; A283-D285 PolarHBondContact O-N 3.25Å; D285-Y287 PolarHBondContact O-N 3.22Å; D285-V521 HydrophobicContact CB-CG1 4.42Å; D285-V521 WeakPolarHBondContact O-CG1 3.34Å
286L97.4Very high98.1Very high67 Ų6755.2 Ų55.235%0.35133%0.33SS..  trans-85.796.2-165.3-165.865.9000112.5V281 A282 A283 P289 E520V281-L286 HydrophobicContact CG1-CD1 4.21Å; A282-L286 PolarHBondContact O-N 3.49Å; A283-L286 PolarHBondContact O-N 2.79Å; L286-P289 HydrophobicContact CD2-CB 4.11Å; L286-P289 HydrophobicContact CD2-CG 3.93Å; L286-P289 HydrophobicContact CG-CB 4.48Å; L286-P289 HydrophobicContact CG-CG 4.09Å; L286-E520 HydrophobicContact CD1-CB 3.8Å; L286-E520 HydrophobicContact CD1-CG 4.11Å
287Y98.3Very high98.1Very high70 Ų7053.8 Ų53.828%0.27532%0.318SS..SBendtrans-84.1-46.7170.5-173.7-96000112D285 P289 E520 E638 K699D285-Y287 PolarHBondContact O-N 3.22Å; Y287-P289 WeakPolarHBondContact O-CD 3.31Å; Y287-E520 PolarHBondContact N-O 2.77Å; Y287-E638 HydrophobicContact CE2-CB 4.11Å; Y287-E638 PolarHBondContact OH-O 3.07Å; Y287-K699 HydrophobicContact CE1-CB 3.9Å; Y287-K699 HydrophobicContact CE1-CG 4.38Å; Y287-K699 WeakPolarHBondContact OH-CB 3.25Å
288T98.2Very high98.1Very high28 Ų2853.7 Ų53.717%0.17232%0.317CS..SBendtrans-116.792.6-179.2-56.20000110N517 E520 F522T288-N517 HydrophobicContact CG2-CB 4.33Å; T288-E520 PolarHBondContact N-O 2.85Å; T288-E520 WeakPolarHBondContact O-CA 3.22Å; T288-F522 PolarHBondContact OG1-O 3.42Å
289P97.9Very high98Very high83 Ų8357.2 Ų57.254%0.53934%0.337SS..PPolyproline II helixtrans-56.2142.8168.2-21.732000111L286 Y287 S291L286-P289 HydrophobicContact CD2-CB 4.11Å; L286-P289 HydrophobicContact CD2-CG 3.93Å; L286-P289 HydrophobicContact CG-CB 4.48Å; L286-P289 HydrophobicContact CG-CG 4.09Å; Y287-P289 WeakPolarHBondContact O-CD 3.31Å; P289-S291 PolarHBondContact O-N 3.49Å
290H98.4Very high98Very high37 Ų3756.6 Ų56.617%0.17134%0.337CS..PPolyproline II helixtrans-57.1130.9173.6-71.7-173.1000109.8L294 Y298 E520H290-L294 HydrophobicContact CB-CB 4.46Å; H290-L294 HydrophobicContact CB-CD2 4.05Å; H290-L294 HydrophobicContact CB-CG 4.4Å; H290-Y298 AromaticContact CE1-CD2 3.98Å; H290-Y298 AromaticContact CE1-CE2 3.75Å; H290-Y298 AromaticContact ND1-CD2 3.93Å; H290-E520 IonicContact CD2-OE1 3.76Å; H290-E520 IonicContact CE1-OE1 2.85Å; H290-E520 PolarHBondContact CE1-OE1 3.38Å; H290-E520 IonicContact NE2-OE1 3.41Å; H290-E520 PolarHBondContact NE2-OE1 3.09Å
291S98.4Very high98Very high28 Ų2856 Ų5620%0.19633%0.334CS..PPolyproline II helixtrans-65.6163.7174.383.30000110.9P289 L293 L294 S295 L515P289-S291 PolarHBondContact O-N 3.49Å; S291-L293 PolarHBondContact O-N 3.22Å; S291-L293 PolarHBondContact OG-N 3.46Å; S291-L294 PolarHBondContact O-N 3.4Å; S291-L294 PolarHBondContact OG-N 2.85Å; S291-L294 VanDerWaalsContact OG-N 3.08Å; S291-S295 WeakPolarHBondContact O-CB 3.46Å; S291-S295 PolarHBondContact O-N 2.85Å; S291-S295 PolarHBondContact O-OG 3.26Å; S291-L515 WeakPolarHBondContact CB-O 3.38Å; S291-L515 PolarHBondContact OG-O 3.06Å
292T98.2Very high98Very high118 Ų11855.7 Ų55.772%0.72433%0.331SS*.Hα-helixtrans-56.6-37.6171-50.20000111.6S295 V296T292-S295 PolarHBondContact O-N 3.48Å; T292-V296 VanDerWaalsContact O-CG2 3.31Å; T292-V296 WeakPolarHBondContact O-CG2 3.42Å; T292-V296 PolarHBondContact O-N 2.89Å
293L98.1Very high98Very high91 Ų9160.4 Ų60.448%0.47635%0.354SS..Hα-helixtrans-63.9-47.7178.1176.963.5000111.2S291 V296 A297 L515 L516S291-L293 PolarHBondContact O-N 3.22Å; S291-L293 PolarHBondContact OG-N 3.46Å; L293-V296 PolarHBondContact O-N 3.46Å; L293-A297 WeakPolarHBondContact O-CB 3.47Å; L293-A297 PolarHBondContact O-N 3.17Å; L293-L515 HydrophobicContact CB-CB 4.42Å; L293-L515 HydrophobicContact CD2-CB 3.92Å; L293-L515 HydrophobicContact CD2-CD1 4.16Å; L293-L516 HydrophobicContact CD2-CD2 3.92Å; L293-L516 HydrophobicContact CD2-CG 4.47Å; L293-L516 HydrophobicContact CG-CD2 3.93Å
294L98.4Very high98Very high7 Ų759.3 Ų59.34%0.03733%0.33CS..Hα-helixtrans-66.1-40.4179-178.959.4000111.6H290 S291 V296 A297 Y298 L515 L516 N517 P518H290-L294 HydrophobicContact CB-CB 4.46Å; H290-L294 HydrophobicContact CB-CD2 4.05Å; H290-L294 HydrophobicContact CB-CG 4.4Å; S291-L294 PolarHBondContact O-N 3.4Å; S291-L294 PolarHBondContact OG-N 2.85Å; S291-L294 VanDerWaalsContact OG-N 3.08Å; L294-V296 VanDerWaalsContact C-N 3.32Å; L294-V296 PolarHBondContact O-N 2.9Å; L294-A297 PolarHBondContact O-N 3.05Å; L294-Y298 HydrophobicContact CD1-CD2 3.7Å; L294-Y298 HydrophobicContact CD1-CE2 3.53Å; L294-Y298 HydrophobicContact CD1-CG 4.35Å; L294-Y298 HydrophobicContact CD2-CD2 4.4Å; L294-Y298 HydrophobicContact CD2-CE2 4Å; L294-Y298 HydrophobicContact CG-CD2 3.74Å; L294-Y298 HydrophobicContact CG-CE2 3.75Å; L294-Y298 PolarHBondContact O-N 3.41Å; L294-L515 WeakPolarHBondContact CB-O 3.32Å; L294-L516 HydrophobicContact CD1-CD2 4.4Å; L294-N517 WeakPolarHBondContact CD2-O 3.4Å; L294-P518 HydrophobicContact CD2-CB 3.96Å
295S97.9Very high98.1Very high45 Ų4556.6 Ų56.632%0.31531%0.311SS..Hα-helixtrans-58.6-45.3176.2-60.50000111.2S291 T292 Y298 M299S291-S295 WeakPolarHBondContact O-CB 3.46Å; S291-S295 PolarHBondContact O-N 2.85Å; S291-S295 PolarHBondContact O-OG 3.26Å; T292-S295 PolarHBondContact O-N 3.48Å; S295-Y298 PolarHBondContact O-N 2.61Å; S295-M299 WeakPolarHBondContact O-CG 3.34Å; S295-M299 PolarHBondContact O-N 3.44Å; S295-M299 VanDerWaalsContact O-N 3.09Å
296V98.1Very high98.1Very high73 Ų7359.5 Ų59.544%0.44234%0.337SS..Hα-helixtrans-66.2-43.9175.2173.10000111.6T292 L293 L294 Y298 M299 V300T292-V296 VanDerWaalsContact O-CG2 3.31Å; T292-V296 WeakPolarHBondContact O-CG2 3.42Å; T292-V296 PolarHBondContact O-N 2.89Å; L293-V296 PolarHBondContact O-N 3.46Å; L294-V296 VanDerWaalsContact C-N 3.32Å; L294-V296 PolarHBondContact O-N 2.9Å; V296-Y298 VanDerWaalsContact C-N 3.35Å; V296-Y298 PolarHBondContact O-N 3.35Å; V296-M299 HydrophobicContact CB-CE 4.22Å; V296-M299 HydrophobicContact CG2-CE 3.85Å; V296-M299 PolarHBondContact O-N 3.22Å; V296-V300 PolarHBondContact O-N 3.18Å
297A97.9Very high98.1Very high27 Ų2763.2 Ų63.222%0.22335%0.352CS..Hα-helixtrans-57.1-49.4175.900000110.5L293 L294 M299 V300 L301L293-A297 WeakPolarHBondContact O-CB 3.47Å; L293-A297 PolarHBondContact O-N 3.17Å; L294-A297 PolarHBondContact O-N 3.05Å; A297-M299 VanDerWaalsContact C-N 3.34Å; A297-M299 PolarHBondContact O-N 3.21Å; A297-V300 PolarHBondContact O-N 2.69Å; A297-V300 VanDerWaalsContact O-N 3.1Å; A297-L301 HydrophobicContact CB-CD1 4.47Å; A297-L301 WeakPolarHBondContact O-CB 3.38Å; A297-L301 WeakPolarHBondContact O-CG 3.35Å; A297-L301 PolarHBondContact O-N 3.04Å
298Y98.5Very high98.1Very high23 Ų2362.7 Ų62.79%0.0935%0.352CS..Hα-helixtrans-64.5-32.4179.2-85.2-41000114N210 T211 H290 L294 S295 V296 V300 L301 N302 P518N210-Y298 HydrophobicContact CB-CD1 3.71Å; N210-Y298 HydrophobicContact CB-CD2 4.05Å; N210-Y298 HydrophobicContact CB-CE1 3.63Å; N210-Y298 HydrophobicContact CB-CE2 3.93Å; N210-Y298 HydrophobicContact CB-CG 3.95Å; T211-Y298 WeakPolarHBondContact O-CE1 3.41Å; H290-Y298 AromaticContact CE1-CD2 3.98Å; H290-Y298 AromaticContact CE1-CE2 3.75Å; H290-Y298 AromaticContact ND1-CD2 3.93Å; L294-Y298 HydrophobicContact CD1-CD2 3.7Å; L294-Y298 HydrophobicContact CD1-CE2 3.53Å; L294-Y298 HydrophobicContact CD1-CG 4.35Å; L294-Y298 HydrophobicContact CD2-CD2 4.4Å; L294-Y298 HydrophobicContact CD2-CE2 4Å; L294-Y298 HydrophobicContact CG-CD2 3.74Å; L294-Y298 HydrophobicContact CG-CE2 3.75Å; L294-Y298 PolarHBondContact O-N 3.41Å; S295-Y298 PolarHBondContact O-N 2.61Å; V296-Y298 VanDerWaalsContact C-N 3.35Å; V296-Y298 PolarHBondContact O-N 3.35Å; Y298-V300 VanDerWaalsContact C-N 3.32Å; Y298-V300 PolarHBondContact O-N 3.02Å; Y298-L301 HydrophobicContact CD1-CD1 4.41Å; Y298-L301 PolarHBondContact O-N 2.93Å; Y298-N302 WeakPolarHBondContact O-CB 3.4Å; Y298-N302 PolarHBondContact O-N 2.88Å; Y298-N302 PolarHBondContact O-ND2 3.31Å; Y298-P518 HydrophobicContact CE2-CB 4Å; Y298-P518 WeakPolarHBondContact OH-CB 3.39Å
299M97.2Very high98.1Very high126 Ų12663.6 Ų63.662%0.62136%0.359SS*.Hα-helixtrans-58.6-46.2171.1-72.8-170.7-68.500111.5S295 V296 A297 L303S295-M299 WeakPolarHBondContact O-CG 3.34Å; S295-M299 PolarHBondContact O-N 3.44Å; S295-M299 VanDerWaalsContact O-N 3.09Å; V296-M299 HydrophobicContact CB-CE 4.22Å; V296-M299 HydrophobicContact CG2-CE 3.85Å; V296-M299 PolarHBondContact O-N 3.22Å; A297-M299 VanDerWaalsContact C-N 3.34Å; A297-M299 PolarHBondContact O-N 3.21Å; M299-L303 PolarHBondContact O-N 3.48Å
300V98.3Very high98.1Very high94 Ų9463.7 Ų63.757%0.5736%0.359SS*.Hα-helixtrans-69.9-45.5179.1178.50000111.3V296 A297 Y298 L303 Y304V296-V300 PolarHBondContact O-N 3.18Å; A297-V300 PolarHBondContact O-N 2.69Å; A297-V300 VanDerWaalsContact O-N 3.1Å; Y298-V300 VanDerWaalsContact C-N 3.32Å; Y298-V300 PolarHBondContact O-N 3.02Å; V300-L303 WeakPolarHBondContact O-CB 3.48Å; V300-L303 PolarHBondContact O-N 2.94Å; V300-Y304 PolarHBondContact O-N 2.8Å
301L98.2Very high98.1Very high46 Ų4665 Ų6524%0.24138%0.376CS..Hα-helixtrans-68.1-38.1-176.8-65.3177.1000112.1T211 L213 A297 Y298 L303 Y304 E305T211-L301 HydrophobicContact CG2-CB 3.66Å; L213-L301 HydrophobicContact CD1-CD2 3.94Å; L213-L301 HydrophobicContact CD2-CD1 3.93Å; L213-L301 HydrophobicContact CD2-CD2 3.53Å; L213-L301 HydrophobicContact CD2-CG 4.31Å; L213-L301 HydrophobicContact CG-CD2 4.3Å; A297-L301 HydrophobicContact CB-CD1 4.47Å; A297-L301 WeakPolarHBondContact O-CB 3.38Å; A297-L301 WeakPolarHBondContact O-CG 3.35Å; A297-L301 PolarHBondContact O-N 3.04Å; Y298-L301 HydrophobicContact CD1-CD1 4.41Å; Y298-L301 PolarHBondContact O-N 2.93Å; L301-L303 VanDerWaalsContact C-N 3.32Å; L301-Y304 WeakPolarHBondContact O-CB 3.32Å; L301-Y304 PolarHBondContact O-N 3.05Å; L301-E305 PolarHBondContact O-N 3.16Å
302N98.5Very high98.1Very high19 Ų1967.3 Ų67.310%0.10239%0.386CS..Hα-helixtrans-69.4-30.3174-72.1-42.2000112.2N210 T211 Y298 E305 A306N210-N302 PolarHBondContact OD1-ND2 2.74Å; T211-N302 PolarHBondContact N-OD1 2.85Å; Y298-N302 WeakPolarHBondContact O-CB 3.4Å; Y298-N302 PolarHBondContact O-N 2.88Å; Y298-N302 PolarHBondContact O-ND2 3.31Å; N302-E305 PolarHBondContact O-N 3.44Å; N302-A306 PolarHBondContact O-N 3.32Å; N302-A306 VanDerWaalsContact O-N 3.15Å
303L98.1Very high98.2Very high113 Ų11362.4 Ų62.459%0.59235%0.354SS*.Hα-helixtrans-68.3-41.1171.4179.164.1000111.2M299 V300 L301 A306 H307M299-L303 PolarHBondContact O-N 3.48Å; V300-L303 WeakPolarHBondContact O-CB 3.48Å; V300-L303 PolarHBondContact O-N 2.94Å; L301-L303 VanDerWaalsContact C-N 3.32Å; L303-A306 PolarHBondContact O-N 3.14Å; L303-H307 PolarHBondContact O-ND1 2.87Å
304Y98.4Very high98.2Very high70 Ų7064.3 Ų64.328%0.27536%0.358SS..Hα-helixtrans-60.5-45.9171.1169.9-94.4000111L213 E215 V300 L301 A306 H307 H308L213-Y304 HydrophobicContact CD1-CD1 3.99Å; L213-Y304 HydrophobicContact CD1-CE1 4.14Å; E215-Y304 HydrophobicContact CG-CE1 4.46Å; E215-Y304 PolarHBondContact OE1-OH 2.9Å; V300-Y304 PolarHBondContact O-N 2.8Å; L301-Y304 WeakPolarHBondContact O-CB 3.32Å; L301-Y304 PolarHBondContact O-N 3.05Å; Y304-A306 VanDerWaalsContact C-N 3.28Å; Y304-A306 PolarHBondContact O-N 3.36Å; Y304-H307 CarbonylContact O-C 3.55Å; Y304-H307 WeakPolarHBondContact O-CA 3.37Å; Y304-H307 PolarHBondContact O-N 2.81Å; Y304-H308 HydrophobicContact CD1-CB 4.34Å; Y304-H308 HydrophobicContact CE1-CB 3.78Å; Y304-H308 WeakPolarHBondContact O-CA 3.43Å; Y304-H308 PolarHBondContact O-N 3.08Å
305E98.4Very high98.2Very high10 Ų1068.7 Ų68.75%0.04738%0.38CS..Hα-helixtrans-54.6-44.2177.8-179.966.9-160.800111.7T211 Y245 R248 L301 N302 H307 H308 R313T211-E305 HydrophobicContact CG2-CB 4.36Å; T211-E305 PolarHBondContact OG1-OE2 3.41Å; Y245-E305 HydrophobicContact CE1-CG 4.47Å; Y245-E305 WeakPolarHBondContact CE1-OE1 3.48Å; Y245-E305 VanDerWaalsContact OH-CD 3.24Å; Y245-E305 VanDerWaalsContact OH-CG 3.27Å; Y245-E305 WeakPolarHBondContact OH-CG 3.36Å; Y245-E305 PolarHBondContact OH-OE1 3.43Å; R248-E305 IonicContact CZ-OE1 3.09Å; R248-E305 IonicContact NH1-OE1 2.79Å; R248-E305 PolarHBondContact NH1-OE1 3.39Å; R248-E305 VanDerWaalsContact NH1-OE1 3.07Å; R248-E305 IonicContact NH2-OE1 3.49Å; R248-E305 PolarHBondContact NH2-OE1 2.86Å; L301-E305 PolarHBondContact O-N 3.16Å; N302-E305 PolarHBondContact O-N 3.44Å; E305-H307 PolarHBondContact O-N 2.92Å; E305-H307 VanDerWaalsContact O-N 3.13Å; E305-H308 PolarHBondContact O-CD2 2.77Å; E305-H308 VanDerWaalsContact O-CD2 3.28Å; E305-H308 PolarHBondContact O-N 3.31Å; E305-R313 IonicContact OE2-NH1 3.76Å
306A97.3Very high98.3Very high74 Ų7466.6 Ų66.661%0.61237%0.365SS*.Hα-helixtrans-62.9-18.7177.600000113.9N302 L303 Y304N302-A306 PolarHBondContact O-N 3.32Å; N302-A306 VanDerWaalsContact O-N 3.15Å; L303-A306 PolarHBondContact O-N 3.14Å; Y304-A306 VanDerWaalsContact C-N 3.28Å; Y304-A306 PolarHBondContact O-N 3.36Å
307H97.9Very high98.3Very high146 Ų14664.3 Ų64.368%0.67635%0.351SS*.THydrogen-bonded Turntrans-131.326.5-177.1-55.188.6000112.3L303 Y304 E305L303-H307 PolarHBondContact O-ND1 2.87Å; Y304-H307 CarbonylContact O-C 3.55Å; Y304-H307 WeakPolarHBondContact O-CA 3.37Å; Y304-H307 PolarHBondContact O-N 2.81Å; E305-H307 PolarHBondContact O-N 2.92Å; E305-H307 VanDerWaalsContact O-N 3.13Å
308H98.3Very high98.3Very high59 Ų5971.7 Ų71.727%0.27337%0.373SS..  trans-64.8150.3-166.777.589.5000111.4Y304 E305 T310Y304-H308 HydrophobicContact CD1-CB 4.34Å; Y304-H308 HydrophobicContact CE1-CB 3.78Å; Y304-H308 WeakPolarHBondContact O-CA 3.43Å; Y304-H308 PolarHBondContact O-N 3.08Å; E305-H308 PolarHBondContact O-CD2 2.77Å; E305-H308 VanDerWaalsContact O-CD2 3.28Å; E305-H308 PolarHBondContact O-N 3.31Å; H308-T310 PolarHBondContact O-N 2.85Å
309S98.4Very high98.4Very high47 Ų4773.2 Ų73.233%0.32938%0.381SS..  trans-72.7119.3173.4172.80000110.1A311 L312 R313S309-A311 PolarHBondContact O-N 2.98Å; S309-A311 PolarHBondContact OG-N 3.4Å; S309-L312 PolarHBondContact O-N 3.31Å; S309-L312 PolarHBondContact OG-N 3.45Å; S309-R313 WeakPolarHBondContact O-CB 3.23Å; S309-R313 PolarHBondContact O-N 2.95Å
310T98Very high98.4Very high85 Ų8567.2 Ų67.252%0.52135%0.352SS..Hα-helixtrans-62.5-31.5175.9-450000112.1H308 K314H308-T310 PolarHBondContact O-N 2.85Å; T310-K314 WeakPolarHBondContact O-CG 3.27Å; T310-K314 PolarHBondContact O-N 2.66Å
311A98.4Very high98.5Very high65 Ų6564.4 Ų64.454%0.53733%0.331SS..Hα-helixtrans-67.9-47.3177.400000111.3S309 K314 M315S309-A311 PolarHBondContact O-N 2.98Å; S309-A311 PolarHBondContact OG-N 3.4Å; A311-K314 PolarHBondContact O-N 3.13Å; A311-M315 WeakPolarHBondContact O-CG 3.28Å; A311-M315 PolarHBondContact O-N 3.43Å; A311-M315 VanDerWaalsContact O-N 3.14Å
312L98.6Very high98.5Very high76 Ų7664 Ų6440%0.39833%0.329SS..Hα-helixtrans-64.9-40.7175.8-65.7179.2000111.4E215 S309 K314 M315 A316E215-L312 HydrophobicContact CG-CB 4.03Å; S309-L312 PolarHBondContact O-N 3.31Å; S309-L312 PolarHBondContact OG-N 3.45Å; L312-K314 VanDerWaalsContact C-N 3.32Å; L312-K314 PolarHBondContact O-N 3.48Å; L312-M315 HydrophobicContact CD2-SD 4.39Å; L312-M315 WeakPolarHBondContact O-CB 3.3Å; L312-M315 PolarHBondContact O-N 3.32Å; L312-M315 VanDerWaalsContact O-N 3.14Å; L312-A316 WeakPolarHBondContact O-CB 3.43Å; L312-A316 PolarHBondContact O-N 2.9Å
313R98.8Very high98.5Very high14 Ų1463.3 Ų63.35%0.05333%0.325CS..Hα-helixtrans-55.4-46.3174.4179.285.8-62131.117.4111.7P214 E215 E305 S309 M315 A316 V317P214-R313 VanDerWaalsContact CA-NH2 3.35Å; P214-R313 VanDerWaalsContact CD-NH1 3.29Å; E215-R313 IonicContact OE1-CZ 3.85Å; E215-R313 IonicContact OE1-NE 3.49Å; E215-R313 IonicContact OE1-NH1 3.24Å; E215-R313 PolarHBondContact OE1-NH1 3.18Å; E215-R313 VanDerWaalsContact OE1-NH1 3.07Å; E215-R313 IonicContact OE1-NH2 3Å; E215-R313 PolarHBondContact OE1-NH2 3.28Å; E215-R313 VanDerWaalsContact OE1-NH2 3.12Å; E215-R313 IonicContact OE2-CZ 3.98Å; E215-R313 IonicContact OE2-NH1 2.67Å; E215-R313 PolarHBondContact OE2-NH1 2.91Å; E215-R313 IonicContact OE2-NH2 3.27Å; E215-R313 PolarHBondContact OE2-NH2 3.17Å; E305-R313 IonicContact OE2-NH1 3.76Å; S309-R313 WeakPolarHBondContact O-CB 3.23Å; S309-R313 PolarHBondContact O-N 2.95Å; R313-M315 PolarHBondContact O-N 2.84Å; R313-A316 PolarHBondContact O-N 3.43Å; R313-V317 VanDerWaalsContact O-CG2 3.27Å; R313-V317 WeakPolarHBondContact O-CG2 3.46Å; R313-V317 PolarHBondContact O-N 2.89Å
314K98.7Very high98.6Very high131 Ų13158 Ų5857%0.5730%0.297SS*.Hα-helixtrans-63.9-38.4177.6-76.3175.5-180178.80112.6T310 A311 L312 R318T310-K314 WeakPolarHBondContact O-CG 3.27Å; T310-K314 PolarHBondContact O-N 2.66Å; A311-K314 PolarHBondContact O-N 3.13Å; L312-K314 VanDerWaalsContact C-N 3.32Å; L312-K314 PolarHBondContact O-N 3.48Å; K314-R318 WeakPolarHBondContact O-CG 3.29Å; K314-R318 PolarHBondContact O-N 2.98Å
315M98.8Very high98.6Very high100 Ų10056.9 Ų56.949%0.49330%0.295SS..Hα-helixtrans-64.8-46.1174.6-69.5173.662.900111L218 A311 L312 R313 V317 R318 E319L218-M315 HydrophobicContact CD1-CB 3.73Å; L218-M315 HydrophobicContact CD2-CB 4.27Å; A311-M315 WeakPolarHBondContact O-CG 3.28Å; A311-M315 PolarHBondContact O-N 3.43Å; A311-M315 VanDerWaalsContact O-N 3.14Å; L312-M315 HydrophobicContact CD2-SD 4.39Å; L312-M315 WeakPolarHBondContact O-CB 3.3Å; L312-M315 PolarHBondContact O-N 3.32Å; L312-M315 VanDerWaalsContact O-N 3.14Å; R313-M315 PolarHBondContact O-N 2.84Å; M315-V317 PolarHBondContact O-N 3.23Å; M315-R318 PolarHBondContact O-N 2.88Å; M315-E319 PolarHBondContact O-N 3.35Å
316A98.9Very high98.6Very high0 Ų056.4 Ų56.40%029%0.293CS..Hα-helixtrans-60.3-46.3178.400000111.3P214 E215 L218 L312 R313 R318 E319 L320P214-A316 HydrophobicContact CB-CB 4.46Å; P214-A316 WeakPolarHBondContact O-CB 3.42Å; E215-A316 HydrophobicContact CG-CB 4.47Å; L218-A316 HydrophobicContact CD1-CB 3.94Å; L218-A316 HydrophobicContact CG-CB 4.08Å; L312-A316 WeakPolarHBondContact O-CB 3.43Å; L312-A316 PolarHBondContact O-N 2.9Å; R313-A316 PolarHBondContact O-N 3.43Å; A316-R318 VanDerWaalsContact C-N 3.26Å; A316-R318 PolarHBondContact O-N 3.25Å; A316-E319 WeakPolarHBondContact O-CB 3.38Å; A316-E319 PolarHBondContact O-N 2.99Å; A316-E319 VanDerWaalsContact O-N 3.12Å; A316-L320 WeakPolarHBondContact O-CB 3.31Å; A316-L320 WeakPolarHBondContact O-CD1 3.47Å; A316-L320 WeakPolarHBondContact O-CG 3.31Å; A316-L320 PolarHBondContact O-N 2.95Å
317V98.9Very high98.7Very high26 Ų2653.1 Ų53.116%0.15827%0.265CS..Hα-helixtrans-57.2-38.4177.1168.80000112.2Y243 A246 V247 R313 M315 Y321Y243-V317 HydrophobicContact CD2-CG1 4.27Å; Y243-V317 HydrophobicContact CE2-CG1 3.57Å; A246-V317 HydrophobicContact CB-CG2 3.56Å; V247-V317 HydrophobicContact CG1-CG1 4.35Å; V247-V317 HydrophobicContact CG1-CG2 4.38Å; R313-V317 VanDerWaalsContact O-CG2 3.27Å; R313-V317 WeakPolarHBondContact O-CG2 3.46Å; R313-V317 PolarHBondContact O-N 2.89Å; M315-V317 PolarHBondContact O-N 3.23Å; V317-Y321 WeakPolarHBondContact O-CB 3.41Å; V317-Y321 PolarHBondContact O-N 3.07Å
318R98.9Very high98.7Very high181 Ų18146.2 Ų46.268%0.68323%0.233SC*.Hα-helixtrans-68-44.3175.5-69.3173.6-172.5168.40.8112K314 M315 A316 Y321 D322K314-R318 WeakPolarHBondContact O-CG 3.29Å; K314-R318 PolarHBondContact O-N 2.98Å; M315-R318 PolarHBondContact O-N 2.88Å; A316-R318 VanDerWaalsContact C-N 3.26Å; A316-R318 PolarHBondContact O-N 3.25Å; R318-Y321 PolarHBondContact O-N 3.47Å; R318-D322 PolarHBondContact O-N 3.25Å
319E98.8Very high98.8Very high56 Ų5649.6 Ų49.626%0.26224%0.243SC..Hα-helixtrans-61.2-47.9177.6-170.166.3-164.400111.3W217 L218 M315 A316 Y321 D322 H323W217-E319 HydrophobicContact CB-CG 4.41Å; L218-E319 HydrophobicContact CD2-CB 4.02Å; L218-E319 HydrophobicContact CD2-CG 4.36Å; M315-E319 PolarHBondContact O-N 3.35Å; A316-E319 WeakPolarHBondContact O-CB 3.38Å; A316-E319 PolarHBondContact O-N 2.99Å; A316-E319 VanDerWaalsContact O-N 3.12Å; E319-Y321 VanDerWaalsContact C-N 3.32Å; E319-Y321 PolarHBondContact O-N 3.05Å; E319-D322 PolarHBondContact O-N 3.47Å; E319-H323 PolarHBondContact O-CD2 3.2Å; E319-H323 PolarHBondContact O-N 2.82Å; E319-H323 IonicContact OE1-CD2 3.29Å; E319-H323 IonicContact OE1-NE2 3.09Å; E319-H323 PolarHBondContact OE1-NE2 3.23Å
320L98.9Very high98.8Very high0 Ų048.6 Ų48.60%023%0.233CC..Hα-helixtrans-58.2-46.6177.3-64.1162.3000110.7P214 W217 L239 Y243 A316 H323 I324P214-L320 HydrophobicContact CB-CD1 3.5Å; P214-L320 VanDerWaalsContact CB-CD1 3.5Å; W217-L320 HydrophobicContact CB-CD2 4.16Å; W217-L320 HydrophobicContact CD2-CD2 3.75Å; W217-L320 HydrophobicContact CG-CD2 3.47Å; W217-L320 VanDerWaalsContact CG-CD2 3.47Å; W217-L320 HydrophobicContact CG-CG 4.45Å; L239-L320 HydrophobicContact CD1-CB 4.03Å; L239-L320 HydrophobicContact CD1-CD2 3.53Å; L239-L320 HydrophobicContact CD1-CG 4.36Å; Y243-L320 HydrophobicContact CD2-CB 4.09Å; A316-L320 WeakPolarHBondContact O-CB 3.31Å; A316-L320 WeakPolarHBondContact O-CD1 3.47Å; A316-L320 WeakPolarHBondContact O-CG 3.31Å; A316-L320 PolarHBondContact O-N 2.95Å; L320-H323 PolarHBondContact O-N 3.46Å; L320-I324 VanDerWaalsContact O-CG1 3.26Å; L320-I324 WeakPolarHBondContact O-CG1 3.12Å; L320-I324 PolarHBondContact O-N 2.97Å
321Y98.9Very high98.8Very high35 Ų3544.6 Ų44.614%0.13721%0.208CC..Hα-helixtrans-63.8-43.2-179.9-172.5-120.3000112.2Y243 V317 R318 E319 H323 I324 Q325 V347 R348 V351 D352Y243-Y321 HydrophobicContact CE2-CD2 4.25Å; Y243-Y321 HydrophobicContact CE2-CG 4.34Å; V317-Y321 WeakPolarHBondContact O-CB 3.41Å; V317-Y321 PolarHBondContact O-N 3.07Å; R318-Y321 PolarHBondContact O-N 3.47Å; E319-Y321 VanDerWaalsContact C-N 3.32Å; E319-Y321 PolarHBondContact O-N 3.05Å; Y321-H323 VanDerWaalsContact C-N 3.32Å; Y321-H323 PolarHBondContact O-N 2.88Å; Y321-I324 PolarHBondContact O-N 3.43Å; Y321-Q325 HydrophobicContact CD1-CG 4.31Å; Y321-Q325 HydrophobicContact CD2-CG 4.46Å; Y321-Q325 VanDerWaalsContact CE1-CD 3.43Å; Y321-Q325 HydrophobicContact CE1-CG 3.95Å; Y321-Q325 VanDerWaalsContact CE1-NE2 3.26Å; Y321-Q325 HydrophobicContact CE2-CG 4.07Å; Y321-Q325 VanDerWaalsContact O-CG 3.29Å; Y321-Q325 WeakPolarHBondContact O-CG 3.35Å; Y321-Q325 PolarHBondContact O-N 3.12Å; Y321-Q325 PolarHBondContact OH-NE2 3.48Å; Y321-Q325 VanDerWaalsContact OH-NE2 3.11Å; Y321-V347 HydrophobicContact CD2-CG1 3.92Å; Y321-V347 HydrophobicContact CE2-CG1 4.19Å; Y321-R348 PolarHBondContact OH-NE 3Å; Y321-R348 PolarHBondContact OH-NH2 3.18Å; Y321-V351 HydrophobicContact CD1-CG1 4.48Å; Y321-V351 HydrophobicContact CD2-CB 4.48Å; Y321-V351 HydrophobicContact CD2-CG1 4.43Å; Y321-V351 HydrophobicContact CD2-CG2 4.13Å; Y321-V351 HydrophobicContact CE1-CG1 3.83Å; Y321-V351 HydrophobicContact CE2-CB 3.8Å; Y321-V351 HydrophobicContact CE2-CG1 3.8Å; Y321-V351 HydrophobicContact CE2-CG2 3.92Å; Y321-V351 VanDerWaalsContact CZ-CG1 3.48Å; Y321-D352 PolarHBondContact OH-OD1 3.47Å; Y321-D352 PolarHBondContact OH-OD2 3.19Å
322D98.9Very high98.8Very high37 Ų3745.9 Ų45.920%0.19820%0.202CC..Hα-helixtrans-59.8-41.8176-17544.3000111.9R318 E319 Q325 A326 K433R318-D322 PolarHBondContact O-N 3.25Å; E319-D322 PolarHBondContact O-N 3.47Å; D322-Q325 PolarHBondContact O-N 3.35Å; D322-A326 PolarHBondContact O-N 2.73Å; D322-K433 IonicContact OD1-NZ 2.78Å; D322-K433 WeakPolarHBondContact OD2-CE 3.27Å; D322-K433 IonicContact OD2-NZ 3.05Å; D322-K433 PolarHBondContact OD2-NZ 2.74Å
323H98.9Very high98.8Very high5 Ų542.2 Ų42.22%0.02318%0.183CC..Hα-helixtrans-65.3-39.1174.5-86.4-105000113.4W217 L239 E319 L320 Y321 A326 D327 Y434 Y435W217-H323 HydrophobicContact CZ3-CB 4.4Å; W217-H323 AromaticContact CZ3-ND1 3.68Å; L239-H323 HydrophobicContact CD1-CB 3.9Å; L239-H323 HydrophobicContact CD2-CB 3.85Å; E319-H323 PolarHBondContact O-CD2 3.2Å; E319-H323 PolarHBondContact O-N 2.82Å; E319-H323 IonicContact OE1-CD2 3.29Å; E319-H323 IonicContact OE1-NE2 3.09Å; E319-H323 PolarHBondContact OE1-NE2 3.23Å; L320-H323 PolarHBondContact O-N 3.46Å; Y321-H323 VanDerWaalsContact C-N 3.32Å; Y321-H323 PolarHBondContact O-N 2.88Å; H323-A326 PolarHBondContact O-N 3.1Å; H323-D327 PolarHBondContact O-N 3.42Å; H323-D327 VanDerWaalsContact O-N 3.12Å; H323-Y434 AromaticContact CE1-CD1 3.96Å; H323-Y434 AromaticContact ND1-CD1 3.94Å; H323-Y435 AromaticContact CE1-CD2 3.85Å; H323-Y435 AromaticContact CE1-CE2 3.34Å; H323-Y435 WeakPolarHBondContact CE1-CE2 3.2Å; H323-Y435 AromaticContact CE1-CZ 3.57Å
324I98.9Very high98.9Very high0 Ų041.6 Ų41.60%018%0.18CC..Hα-helixtrans-63.5-45.3173.9-69.6164.4000110L239 P240 Y243 L320 Y321 A326 D327 D328 N344 V347L239-I324 HydrophobicContact CD1-CG1 4.28Å; L239-I324 HydrophobicContact CD2-CG1 3.82Å; L239-I324 HydrophobicContact CG-CD1 4.36Å; L239-I324 HydrophobicContact CG-CG1 3.75Å; P240-I324 HydrophobicContact CB-CD1 3.93Å; P240-I324 HydrophobicContact CB-CG1 4.34Å; Y243-I324 HydrophobicContact CD2-CD1 4.34Å; Y243-I324 HydrophobicContact CG-CD1 4.27Å; L320-I324 VanDerWaalsContact O-CG1 3.26Å; L320-I324 WeakPolarHBondContact O-CG1 3.12Å; L320-I324 PolarHBondContact O-N 2.97Å; Y321-I324 PolarHBondContact O-N 3.43Å; I324-A326 VanDerWaalsContact C-N 3.25Å; I324-A326 PolarHBondContact O-N 3.45Å; I324-D327 PolarHBondContact O-N 3.48Å; I324-D328 PolarHBondContact O-N 2.98Å; I324-N344 HydrophobicContact CG2-CB 4.08Å; I324-V347 HydrophobicContact CD1-CB 4.34Å; I324-V347 HydrophobicContact CD1-CG1 3.92Å; I324-V347 HydrophobicContact CD1-CG2 4.19Å; I324-V347 HydrophobicContact CG2-CG1 4.44Å
325Q98.9Very high98.9Very high48 Ų4835.3 Ų35.322%0.22415%0.153CC..Hα-helixtrans-60.8-36.2176.5-68.9-172.3-46.400112Y321 D322 R329Y321-Q325 HydrophobicContact CD1-CG 4.31Å; Y321-Q325 HydrophobicContact CD2-CG 4.46Å; Y321-Q325 VanDerWaalsContact CE1-CD 3.43Å; Y321-Q325 HydrophobicContact CE1-CG 3.95Å; Y321-Q325 VanDerWaalsContact CE1-NE2 3.26Å; Y321-Q325 HydrophobicContact CE2-CG 4.07Å; Y321-Q325 VanDerWaalsContact O-CG 3.29Å; Y321-Q325 WeakPolarHBondContact O-CG 3.35Å; Y321-Q325 PolarHBondContact O-N 3.12Å; Y321-Q325 PolarHBondContact OH-NE2 3.48Å; Y321-Q325 VanDerWaalsContact OH-NE2 3.11Å; D322-Q325 PolarHBondContact O-N 3.35Å; Q325-R329 VanDerWaalsContact O-CG 3.3Å; Q325-R329 WeakPolarHBondContact O-CG 3.42Å; Q325-R329 PolarHBondContact O-N 3.05Å; Q325-R329 VanDerWaalsContact O-N 3.09Å; Q325-R329 PolarHBondContact O-NH1 3.39Å
326A98.9Very high98.9Very high0 Ų030.7 Ų30.70%013%0.13CC..Hα-helixtrans-65.5-47.5176.300000112.3D322 H323 I324 D328 R329 F330 Y434D322-A326 PolarHBondContact O-N 2.73Å; H323-A326 PolarHBondContact O-N 3.1Å; I324-A326 VanDerWaalsContact C-N 3.25Å; I324-A326 PolarHBondContact O-N 3.45Å; A326-D328 VanDerWaalsContact C-N 3.34Å; A326-D328 PolarHBondContact O-N 2.8Å; A326-R329 PolarHBondContact O-N 2.83Å; A326-F330 HydrophobicContact CB-CE2 3.99Å; A326-F330 HydrophobicContact CB-CZ 4.15Å; A326-F330 WeakPolarHBondContact O-CB 3.39Å; A326-F330 WeakPolarHBondContact O-CD1 3.44Å; A326-F330 VanDerWaalsContact O-CD2 3.29Å; A326-F330 WeakPolarHBondContact O-CD2 3.47Å; A326-F330 WeakPolarHBondContact O-CG 3.28Å; A326-F330 PolarHBondContact O-N 3.11Å; A326-Y434 HydrophobicContact CB-CD1 3.34Å; A326-Y434 HydrophobicContact CB-CD2 3.64Å; A326-Y434 HydrophobicContact CB-CE1 3.51Å; A326-Y434 HydrophobicContact CB-CE2 3.8Å; A326-Y434 HydrophobicContact CB-CG 3.38Å
327D98.9Very high98.9Very high4 Ų430.9 Ų30.92%0.02113%0.132CC..Hα-helixtrans-60.9-43.4177.2-173.459.3000111.6H323 I324 R329 F330 T331 S335 N344 W452H323-D327 PolarHBondContact O-N 3.42Å; H323-D327 VanDerWaalsContact O-N 3.12Å; I324-D327 PolarHBondContact O-N 3.48Å; D327-R329 VanDerWaalsContact C-N 3.34Å; D327-R329 PolarHBondContact O-N 2.72Å; D327-F330 PolarHBondContact O-N 3.21Å; D327-T331 WeakPolarHBondContact O-CB 3.36Å; D327-T331 VanDerWaalsContact O-CG2 3.32Å; D327-T331 WeakPolarHBondContact O-CG2 3.35Å; D327-T331 PolarHBondContact O-N 3.42Å; D327-T331 PolarHBondContact O-OG1 3.43Å; D327-S335 VanDerWaalsContact OD2-CA 3.32Å; D327-S335 WeakPolarHBondContact OD2-CA 3.42Å; D327-S335 WeakPolarHBondContact OD2-CB 3.43Å; D327-S335 PolarHBondContact OD2-OG 3.16Å; D327-N344 PolarHBondContact OD2-ND2 2.51Å; D327-W452 PolarHBondContact OD1-NE1 3.32Å; D327-W452 VanDerWaalsContact OD1-NE1 3.13Å
328D98.9Very high98.9Very high2 Ų230 Ų301%0.01113%0.127CC..Hα-helixtrans-58.6-44.3176.4-70.8-12.1000112.1I324 A326 K332 C333 N344 R348 H362I324-D328 PolarHBondContact O-N 2.98Å; A326-D328 VanDerWaalsContact C-N 3.34Å; A326-D328 PolarHBondContact O-N 2.8Å; D328-K332 WeakPolarHBondContact O-CA 3.43Å; D328-K332 PolarHBondContact O-N 3.11Å; D328-C333 PolarHBondContact O-N 3.19Å; D328-N344 PolarHBondContact OD1-ND2 2.87Å; D328-N344 VanDerWaalsContact OD1-ND2 3.11Å; D328-R348 WeakPolarHBondContact OD2-CD 3.33Å; D328-R348 WeakPolarHBondContact OD2-CG 3.33Å; D328-R348 IonicContact OD2-CZ 2.76Å; D328-R348 IonicContact OD2-NE 3.22Å; D328-R348 IonicContact OD2-NH1 3.62Å; D328-R348 PolarHBondContact OD2-NH1 2.91Å; D328-H362 IonicContact OD1-CE1 2.73Å; D328-H362 PolarHBondContact OD1-CE1 3.5Å; D328-H362 VanDerWaalsContact OD1-CE1 3.3Å; D328-H362 IonicContact OD1-NE2 3.74Å; D328-H362 PolarHBondContact OD1-NE2 3.09Å; D328-H362 IonicContact OD2-CD2 3.99Å; D328-H362 IonicContact OD2-NE2 3.85Å; D328-H362 PolarHBondContact OD2-NE2 3.27Å
329R98.8Very high98.9Very high129 Ų12922.3 Ų22.349%0.48710%0.099SC..Hα-helixtrans-64.6-42.1176.3-73.2-173.8-54.7-98.74.3112.3Q325 A326 D327 T331Q325-R329 VanDerWaalsContact O-CG 3.3Å; Q325-R329 WeakPolarHBondContact O-CG 3.42Å; Q325-R329 PolarHBondContact O-N 3.05Å; Q325-R329 VanDerWaalsContact O-N 3.09Å; Q325-R329 PolarHBondContact O-NH1 3.39Å; A326-R329 PolarHBondContact O-N 2.83Å; D327-R329 VanDerWaalsContact C-N 3.34Å; D327-R329 PolarHBondContact O-N 2.72Å; R329-T331 VanDerWaalsContact C-N 3.27Å; R329-T331 PolarHBondContact O-N 2.87Å
330F98.8Very high98.9Very high27 Ų2719.7 Ų19.712%0.1189%0.087CC..Hα-helixtrans-74.6-20.2-174.5-61.2-16.3000113.4A326 D327 P428 P429 Y434 R436A326-F330 HydrophobicContact CB-CE2 3.99Å; A326-F330 HydrophobicContact CB-CZ 4.15Å; A326-F330 WeakPolarHBondContact O-CB 3.39Å; A326-F330 WeakPolarHBondContact O-CD1 3.44Å; A326-F330 VanDerWaalsContact O-CD2 3.29Å; A326-F330 WeakPolarHBondContact O-CD2 3.47Å; A326-F330 WeakPolarHBondContact O-CG 3.28Å; A326-F330 PolarHBondContact O-N 3.11Å; D327-F330 PolarHBondContact O-N 3.21Å; F330-P428 HydrophobicContact CB-CB 4.4Å; F330-P428 HydrophobicContact CB-CG 4.36Å; F330-P428 HydrophobicContact CD1-CB 3.44Å; F330-P428 VanDerWaalsContact CD1-CB 3.44Å; F330-P428 HydrophobicContact CD1-CG 4.3Å; F330-P428 HydrophobicContact CD2-CB 4.1Å; F330-P428 HydrophobicContact CD2-CG 4.43Å; F330-P428 HydrophobicContact CE1-CB 3.56Å; F330-P428 HydrophobicContact CE2-CB 4.2Å; F330-P428 HydrophobicContact CG-CB 3.72Å; F330-P428 HydrophobicContact CG-CG 4.12Å; F330-P428 HydrophobicContact CZ-CB 3.94Å; F330-P429 HydrophobicContact CE1-CG 4.3Å; F330-P429 WeakPolarHBondContact CE1-O 3.32Å; F330-P429 VanDerWaalsContact CZ-O 3.27Å; F330-P429 WeakPolarHBondContact CZ-O 3.42Å; F330-Y434 AromaticContact CE2-CD2 3.74Å; F330-Y434 HydrophobicContact CE2-CD2 3.74Å; F330-Y434 HydrophobicContact CE2-CG 4.19Å; F330-Y434 AromaticContact CZ-CD2 3.59Å; F330-Y434 HydrophobicContact CZ-CD2 3.59Å; F330-Y434 HydrophobicContact CZ-CE2 4.04Å; F330-Y434 HydrophobicContact CZ-CG 4.45Å; F330-R436 HydrophobicContact CD2-CG 4.09Å; F330-R436 HydrophobicContact CE2-CG 4.19Å
331T98.8Very high98.9Very high0 Ų019.7 Ų19.70%09%0.087CC..Hα-helixtrans-120.75.8-172.866.10000112.9D327 R329 C333 I334 S335 D449 C450D327-T331 WeakPolarHBondContact O-CB 3.36Å; D327-T331 VanDerWaalsContact O-CG2 3.32Å; D327-T331 WeakPolarHBondContact O-CG2 3.35Å; D327-T331 PolarHBondContact O-N 3.42Å; D327-T331 PolarHBondContact O-OG1 3.43Å; R329-T331 VanDerWaalsContact C-N 3.27Å; R329-T331 PolarHBondContact O-N 2.87Å; T331-C333 PolarHBondContact O-N 2.84Å; T331-I334 VanDerWaalsContact O-CB 3.25Å; T331-I334 WeakPolarHBondContact O-CB 3.4Å; T331-I334 WeakPolarHBondContact O-CD1 3.21Å; T331-I334 WeakPolarHBondContact O-CG1 3.36Å; T331-I334 PolarHBondContact O-N 2.94Å; T331-I334 PolarHBondContact OG1-N 2.78Å; T331-S335 WeakPolarHBondContact OG1-CA 3.33Å; T331-S335 PolarHBondContact OG1-N 2.81Å; T331-D449 CarbonylContact C-O 3.51Å; T331-D449 VanDerWaalsContact C-O 3.31Å; T331-D449 WeakPolarHBondContact CA-O 3.48Å; T331-D449 VanDerWaalsContact O-O 3.12Å; T331-C450 WeakPolarHBondContact CG2-O 3.33Å
332K98.7Very high98.9Very high92 Ų9218.1 Ų18.140%0.48%0.081SC..THydrogen-bonded Turntrans49.347.4-173.1-57.4177.6-177.2173.60111.7D328 I334 R365 D449D328-K332 WeakPolarHBondContact O-CA 3.43Å; D328-K332 PolarHBondContact O-N 3.11Å; K332-I334 VanDerWaalsContact C-N 3.26Å; K332-I334 PolarHBondContact O-N 3.37Å; K332-R365 WeakPolarHBondContact O-CG 3.26Å; K332-R365 PolarHBondContact O-NE 2.89Å; K332-R365 VanDerWaalsContact O-NE 3.08Å; K332-D449 HydrophobicContact CD-CB 4.32Å; K332-D449 WeakPolarHBondContact CD-OD2 3.48Å; K332-D449 WeakPolarHBondContact CE-OD1 3.21Å; K332-D449 IonicContact NZ-OD1 3.19Å; K332-D449 PolarHBondContact NZ-OD1 2.95Å; K332-D449 IonicContact NZ-OD2 2.77Å; K332-D449 PolarHBondContact NZ-OD2 3.31Å
333C98.9Very high98.9Very high0 Ų016.3 Ų16.30%07%0.071CC..THydrogen-bonded Turntrans61.720.9-177.8-56.60000116D328 T331 E361 H362 R365D328-C333 PolarHBondContact O-N 3.19Å; T331-C333 PolarHBondContact O-N 2.84Å; C333-E361 HydrophobicContact CB-CG 4.09Å; C333-H362 HydrophobicContact CB-CB 4.32Å; C333-H362 VanDerWaalsContact SG-CD2 3.59Å; C333-R365 HydrophobicContact CB-CG 4.34Å
334I98.9Very high98.9Very high0 Ų016.1 Ų16.10%07%0.07CC..  trans-86.7-29.7173.3-68.1157.9000111.8T331 K332 K341 R365 Y369 N383 D449 C450T331-I334 VanDerWaalsContact O-CB 3.25Å; T331-I334 WeakPolarHBondContact O-CB 3.4Å; T331-I334 WeakPolarHBondContact O-CD1 3.21Å; T331-I334 WeakPolarHBondContact O-CG1 3.36Å; T331-I334 PolarHBondContact O-N 2.94Å; T331-I334 PolarHBondContact OG1-N 2.78Å; K332-I334 VanDerWaalsContact C-N 3.26Å; K332-I334 PolarHBondContact O-N 3.37Å; I334-K341 WeakPolarHBondContact O-CB 3.17Å; I334-K341 WeakPolarHBondContact O-CG 3.22Å; I334-R365 HydrophobicContact CG1-CG 4.22Å; I334-Y369 HydrophobicContact CG2-CE2 4Å; I334-Y369 WeakPolarHBondContact CG2-OH 3.48Å; I334-Y369 WeakPolarHBondContact O-CE2 3.47Å; I334-Y369 PolarHBondContact O-OH 3.04Å; I334-N383 HydrophobicContact CG2-CB 3.94Å; I334-D449 HydrophobicContact CD1-CB 3.63Å; I334-C450 HydrophobicContact CG2-CB 4.11Å
335S98.9Very high98.9Very high0 Ų016.1 Ų16.10%07%0.07CC..  trans57.9-170.8-169.8-160.80000113.6D327 T331 S340D327-S335 VanDerWaalsContact OD2-CA 3.32Å; D327-S335 WeakPolarHBondContact OD2-CA 3.42Å; D327-S335 WeakPolarHBondContact OD2-CB 3.43Å; D327-S335 PolarHBondContact OD2-OG 3.16Å; T331-S335 WeakPolarHBondContact OG1-CA 3.33Å; T331-S335 PolarHBondContact OG1-N 2.81Å; S335-S340 WeakPolarHBondContact CB-OG 3.3Å; S335-S340 WeakPolarHBondContact OG-CB 3.46Å; S335-S340 PolarHBondContact OG-OG 2.86Å
336I98.8Very high98.9Very high3 Ų313.8 Ų13.82%0.0156%0.06CC..SBendtrans-77-23.2175.4-165.8173.4000112.8C232 Q236 W452 Y504C232-I336 HydrophobicContact CB-CD1 3.89Å; C232-I336 VanDerWaalsContact SG-CD1 3.53Å; Q236-I336 HydrophobicContact CB-CG2 3.81Å; Q236-I336 HydrophobicContact CG-CG2 4.15Å; I336-W452 HydrophobicContact CB-CD2 4.04Å; I336-W452 HydrophobicContact CB-CG 3.98Å; I336-W452 HydrophobicContact CB-CZ2 4.48Å; I336-W452 HydrophobicContact CD1-CD2 3.86Å; I336-W452 HydrophobicContact CD1-CE3 3.81Å; I336-W452 HydrophobicContact CD1-CG 4.26Å; I336-W452 HydrophobicContact CD1-CZ3 4.2Å; I336-W452 HydrophobicContact CG1-CB 4.14Å; I336-W452 HydrophobicContact CG1-CD2 3.91Å; I336-W452 HydrophobicContact CG1-CE3 4.36Å; I336-W452 HydrophobicContact CG1-CG 3.82Å; I336-Y504 HydrophobicContact CD1-CD1 4.03Å; I336-Y504 HydrophobicContact CD1-CD2 4.41Å; I336-Y504 HydrophobicContact CD1-CE1 3.88Å; I336-Y504 HydrophobicContact CD1-CE2 4.31Å; I336-Y504 HydrophobicContact CD1-CG 4.3Å; I336-Y504 HydrophobicContact CG1-CE1 4Å
337G98.6Very high98.9Very high3 Ų313.8 Ų13.83%0.0316%0.06CC..SBendtrans-169.6176.6-177.900000113.2I339 S340 K341 Y369G337-I339 VanDerWaalsContact C-N 3.33Å; G337-I339 PolarHBondContact O-N 3.23Å; G337-S340 PolarHBondContact O-OG 3Å; G337-K341 VanDerWaalsContact O-CB 3.22Å; G337-K341 WeakPolarHBondContact O-CB 3.45Å; G337-K341 PolarHBondContact O-N 2.98Å; G337-K341 VanDerWaalsContact O-N 3.07Å; G337-Y369 VanDerWaalsContact C-OH 3.3Å; G337-Y369 WeakPolarHBondContact CA-OH 3.08Å; G337-Y369 PolarHBondContact O-OH 3.05Å
338P98.8Very high98.9Very high8 Ų814.1 Ų14.15%0.0526%0.06CC..Hα-helixtrans-63.2-36.3-16923.9-34.6000113.1L105 T342 Y369 M379 Q380 G381L105-P338 HydrophobicContact CD1-CG 3.99Å; L105-P338 HydrophobicContact CD2-CB 4.41Å; L105-P338 HydrophobicContact CD2-CG 3.72Å; L105-P338 HydrophobicContact CG-CG 4.35Å; P338-T342 VanDerWaalsContact O-CB 3.26Å; P338-T342 WeakPolarHBondContact O-CB 3.46Å; P338-T342 PolarHBondContact O-N 2.69Å; P338-T342 PolarHBondContact O-OG1 3.35Å; P338-Y369 HydrophobicContact CB-CD1 3.72Å; P338-Y369 HydrophobicContact CB-CE1 3.79Å; P338-Y369 HydrophobicContact CG-CE1 4.33Å; P338-M379 HydrophobicContact CB-CE 3.5Å; P338-M379 VanDerWaalsContact CB-CE 3.5Å; P338-M379 HydrophobicContact CB-CG 4.38Å; P338-M379 HydrophobicContact CB-SD 4.08Å; P338-Q380 WeakPolarHBondContact CG-O 3.31Å; P338-G381 WeakPolarHBondContact CD-O 3.37Å
339I98.9Very high98.9Very high19 Ų1916.9 Ų16.910%0.0977%0.071CC..Hα-helixtrans-73.2-55.2-174.2-59.6166.7000110.6F104 L105 W193 V237 G337 K341 T342 I343F104-I339 HydrophobicContact CD2-CD1 3.89Å; F104-I339 HydrophobicContact CE2-CD1 3.55Å; L105-I339 HydrophobicContact CD2-CD1 3.85Å; L105-I339 HydrophobicContact CD2-CG1 3.69Å; W193-I339 HydrophobicContact CE3-CD1 4.27Å; W193-I339 HydrophobicContact CH2-CD1 4.1Å; W193-I339 HydrophobicContact CZ3-CD1 3.42Å; W193-I339 VanDerWaalsContact CZ3-CD1 3.42Å; V237-I339 HydrophobicContact CB-CG2 4.43Å; V237-I339 HydrophobicContact CG1-CG2 3.72Å; V237-I339 HydrophobicContact CG2-CB 4Å; V237-I339 HydrophobicContact CG2-CG2 3.85Å; G337-I339 VanDerWaalsContact C-N 3.33Å; G337-I339 PolarHBondContact O-N 3.23Å; I339-K341 VanDerWaalsContact C-N 3.28Å; I339-K341 PolarHBondContact O-N 3.19Å; I339-T342 PolarHBondContact O-N 3.22Å; I339-I343 HydrophobicContact CG2-CD1 3.83Å; I339-I343 HydrophobicContact CG2-CG1 4.5Å; I339-I343 WeakPolarHBondContact O-CG1 3.43Å; I339-I343 PolarHBondContact O-N 2.94Å
340S98.9Very high98.9Very high2 Ų216.1 Ų16.11%0.0147%0.069CC..Hα-helixtrans-58.8-42.1176.856.80000110.9Q236 S335 G337 T342 I343 N344Q236-S340 WeakPolarHBondContact O-CB 3.35Å; S335-S340 WeakPolarHBondContact CB-OG 3.3Å; S335-S340 WeakPolarHBondContact OG-CB 3.46Å; S335-S340 PolarHBondContact OG-OG 2.86Å; G337-S340 PolarHBondContact O-OG 3Å; S340-T342 VanDerWaalsContact C-N 3.28Å; S340-T342 PolarHBondContact O-N 3.37Å; S340-I343 PolarHBondContact O-N 3.18Å; S340-N344 VanDerWaalsContact O-CB 3.22Å; S340-N344 WeakPolarHBondContact O-CB 3.43Å; S340-N344 PolarHBondContact O-N 2.96Å; S340-N344 PolarHBondContact O-OD1 3.09Å
341K98.9Very high98.9Very high0 Ų017.7 Ų17.70%08%0.08CC..Hα-helixtrans-53-45.9172.4-178-96.3-179.6-68.60112.6I334 G337 I339 M345 H362 Y369I334-K341 WeakPolarHBondContact O-CB 3.17Å; I334-K341 WeakPolarHBondContact O-CG 3.22Å; G337-K341 VanDerWaalsContact O-CB 3.22Å; G337-K341 WeakPolarHBondContact O-CB 3.45Å; G337-K341 PolarHBondContact O-N 2.98Å; G337-K341 VanDerWaalsContact O-N 3.07Å; I339-K341 VanDerWaalsContact C-N 3.28Å; I339-K341 PolarHBondContact O-N 3.19Å; K341-M345 WeakPolarHBondContact O-CB 3.31Å; K341-M345 PolarHBondContact O-N 2.67Å; K341-H362 PolarHBondContact NZ-ND1 2.99Å; K341-H362 PolarHBondContact NZ-O 3.5Å; K341-Y369 HydrophobicContact CB-CE2 4.16Å; K341-Y369 HydrophobicContact CD-CD2 4.14Å; K341-Y369 HydrophobicContact CD-CE2 4.09Å; K341-Y369 HydrophobicContact CG-CD2 4.37Å; K341-Y369 HydrophobicContact CG-CE2 3.81Å
342T98.9Very high98.9Very high1 Ų120.2 Ų20.21%0.0069%0.094CC..Hα-helixtrans-73.6-39.9-172.9-62.90000111.7G108 L109 T112 W197 P338 I339 S340 M345 L346G108-T342 WeakPolarHBondContact O-CG2 3.24Å; L109-T342 HydrophobicContact CB-CG2 4.44Å; T112-T342 HydrophobicContact CG2-CG2 4.41Å; T112-T342 WeakPolarHBondContact OG1-CG2 3.47Å; W197-T342 HydrophobicContact CH2-CG2 3.88Å; P338-T342 VanDerWaalsContact O-CB 3.26Å; P338-T342 WeakPolarHBondContact O-CB 3.46Å; P338-T342 PolarHBondContact O-N 2.69Å; P338-T342 PolarHBondContact O-OG1 3.35Å; I339-T342 PolarHBondContact O-N 3.22Å; S340-T342 VanDerWaalsContact C-N 3.28Å; S340-T342 PolarHBondContact O-N 3.37Å; T342-M345 WeakPolarHBondContact O-CB 3.34Å; T342-L346 PolarHBondContact O-N 2.84Å; T342-L346 VanDerWaalsContact O-N 3.15Å
343I98.9Very high98.9Very high0 Ų016.6 Ų16.60%08%0.083CC..Hα-helixtrans-76-37.1178-47.6166.4000109.8F196 W197 P240 M241 I339 S340 M345 L346 V347F196-I343 HydrophobicContact CE1-CD1 3.89Å; F196-I343 HydrophobicContact CE1-CG1 4.25Å; F196-I343 HydrophobicContact CE1-CG2 4.42Å; F196-I343 HydrophobicContact CZ-CD1 4.26Å; F196-I343 HydrophobicContact CZ-CG2 3.98Å; W197-I343 HydrophobicContact CH2-CD1 4.31Å; W197-I343 HydrophobicContact CH2-CG1 3.49Å; W197-I343 VanDerWaalsContact CH2-CG1 3.49Å; W197-I343 HydrophobicContact CZ2-CD1 4.02Å; W197-I343 HydrophobicContact CZ2-CG1 3.65Å; W197-I343 HydrophobicContact CZ3-CG1 4.47Å; P240-I343 HydrophobicContact CB-CB 3.81Å; P240-I343 HydrophobicContact CB-CG2 3.59Å; P240-I343 HydrophobicContact CG-CB 3.81Å; P240-I343 HydrophobicContact CG-CD1 4.47Å; P240-I343 HydrophobicContact CG-CG2 4.03Å; M241-I343 HydrophobicContact CE-CD1 3.89Å; M241-I343 HydrophobicContact CG-CD1 3.54Å; I339-I343 HydrophobicContact CG2-CD1 3.83Å; I339-I343 HydrophobicContact CG2-CG1 4.5Å; I339-I343 WeakPolarHBondContact O-CG1 3.43Å; I339-I343 PolarHBondContact O-N 2.94Å; S340-I343 PolarHBondContact O-N 3.18Å; I343-M345 VanDerWaalsContact C-N 3.33Å; I343-M345 PolarHBondContact O-N 2.67Å; I343-L346 WeakPolarHBondContact O-CB 3.29Å; I343-L346 PolarHBondContact O-N 2.93Å; I343-L346 VanDerWaalsContact O-N 3.13Å; I343-V347 WeakPolarHBondContact O-CG2 3.32Å; I343-V347 PolarHBondContact O-N 2.92Å
344N98.9Very high98.8Very high0 Ų019.8 Ų19.80%010%0.103CC..Hα-helixtrans-55.5-49.4170.2-75.110.3000110.5P240 I324 D327 D328 S340 L346 V347 R348P240-N344 WeakPolarHBondContact CB-OD1 3.36Å; P240-N344 WeakPolarHBondContact CG-OD1 3.31Å; I324-N344 HydrophobicContact CG2-CB 4.08Å; D327-N344 PolarHBondContact OD2-ND2 2.51Å; D328-N344 PolarHBondContact OD1-ND2 2.87Å; D328-N344 VanDerWaalsContact OD1-ND2 3.11Å; S340-N344 VanDerWaalsContact O-CB 3.22Å; S340-N344 WeakPolarHBondContact O-CB 3.43Å; S340-N344 PolarHBondContact O-N 2.96Å; S340-N344 PolarHBondContact O-OD1 3.09Å; N344-L346 VanDerWaalsContact C-N 3.27Å; N344-L346 PolarHBondContact O-N 3.34Å; N344-V347 CarbonylContact O-C 3.59Å; N344-V347 WeakPolarHBondContact O-CA 3.42Å; N344-V347 WeakPolarHBondContact O-CB 3.11Å; N344-V347 PolarHBondContact O-N 2.85Å; N344-R348 VanDerWaalsContact O-CG 3.27Å; N344-R348 WeakPolarHBondContact O-CG 3.15Å; N344-R348 PolarHBondContact O-N 3.37Å
345M98.9Very high98.8Very high0 Ų026 Ų260%014%0.142CC..Hα-helixtrans-53.5-43.3175.7177.9164.776.700112.4L109 T112 I118 K341 T342 I343 R348 W349 F359 H362 I366L109-M345 HydrophobicContact CD1-CE 3.93Å; T112-M345 HydrophobicContact CG2-CE 3.63Å; T112-M345 HydrophobicContact CG2-CG 4.4Å; I118-M345 HydrophobicContact CD1-CE 3.85Å; I118-M345 HydrophobicContact CD1-CG 4.5Å; I118-M345 HydrophobicContact CD1-SD 4.01Å; K341-M345 WeakPolarHBondContact O-CB 3.31Å; K341-M345 PolarHBondContact O-N 2.67Å; T342-M345 WeakPolarHBondContact O-CB 3.34Å; I343-M345 VanDerWaalsContact C-N 3.33Å; I343-M345 PolarHBondContact O-N 2.67Å; M345-R348 PolarHBondContact O-N 3.35Å; M345-W349 PolarHBondContact O-N 3.44Å; M345-F359 HydrophobicContact CG-CD2 4.22Å; M345-F359 HydrophobicContact CG-CE2 3.85Å; M345-H362 HydrophobicContact CB-CB 3.95Å; M345-H362 HydrophobicContact CG-CB 3.72Å; M345-H362 HydrophobicContact SD-CB 3.98Å; M345-I366 HydrophobicContact CE-CD1 3.8Å; M345-I366 HydrophobicContact CE-CG1 3.97Å; M345-I366 HydrophobicContact SD-CD1 3.81Å; M345-I366 HydrophobicContact SD-CG1 3.86Å
346L98.9Very high98.8Very high0 Ų027 Ų270%015%0.149CC..Hα-helixtrans-65.2-41.2175.8-177.263.1000112.3T112 I115 V200 L249 T342 I343 N344 W349 Y350T112-L346 HydrophobicContact CG2-CB 3.88Å; T112-L346 HydrophobicContact CG2-CD1 4.23Å; I115-L346 HydrophobicContact CB-CD1 4.27Å; I115-L346 HydrophobicContact CG2-CD1 3.88Å; V200-L346 HydrophobicContact CG1-CD2 3.61Å; L249-L346 HydrophobicContact CD1-CD1 4.49Å; L249-L346 HydrophobicContact CD1-CD2 4.26Å; L249-L346 HydrophobicContact CD1-CG 3.98Å; L249-L346 HydrophobicContact CD2-CD1 4.27Å; L249-L346 HydrophobicContact CD2-CD2 3.94Å; L249-L346 HydrophobicContact CD2-CG 4.23Å; T342-L346 PolarHBondContact O-N 2.84Å; T342-L346 VanDerWaalsContact O-N 3.15Å; I343-L346 WeakPolarHBondContact O-CB 3.29Å; I343-L346 PolarHBondContact O-N 2.93Å; I343-L346 VanDerWaalsContact O-N 3.13Å; N344-L346 VanDerWaalsContact C-N 3.27Å; N344-L346 PolarHBondContact O-N 3.34Å; L346-W349 HydrophobicContact CD1-CE3 3.73Å; L346-W349 HydrophobicContact CD1-CZ3 4.11Å; L346-W349 WeakPolarHBondContact O-CB 3.31Å; L346-W349 PolarHBondContact O-N 3.34Å; L346-Y350 WeakPolarHBondContact O-CB 3.32Å; L346-Y350 PolarHBondContact O-N 2.85Å
347V98.9Very high98.8Very high0 Ų031 Ų310%018%0.182CC..Hα-helixtrans-63.5-43175.1173.10000110.9P240 Y243 Y321 I324 I343 N344 W349 Y350 V351P240-V347 HydrophobicContact CB-CG2 4.26Å; Y243-V347 HydrophobicContact CD1-CB 4.25Å; Y243-V347 HydrophobicContact CD1-CG1 3.69Å; Y243-V347 HydrophobicContact CD1-CG2 3.59Å; Y243-V347 HydrophobicContact CD2-CG1 4.28Å; Y243-V347 HydrophobicContact CE1-CG1 3.76Å; Y243-V347 HydrophobicContact CE1-CG2 4.32Å; Y243-V347 HydrophobicContact CE2-CG1 4.32Å; Y243-V347 HydrophobicContact CG-CG1 3.99Å; Y243-V347 HydrophobicContact CG-CG2 4.02Å; Y321-V347 HydrophobicContact CD2-CG1 3.92Å; Y321-V347 HydrophobicContact CE2-CG1 4.19Å; I324-V347 HydrophobicContact CD1-CB 4.34Å; I324-V347 HydrophobicContact CD1-CG1 3.92Å; I324-V347 HydrophobicContact CD1-CG2 4.19Å; I324-V347 HydrophobicContact CG2-CG1 4.44Å; I343-V347 WeakPolarHBondContact O-CG2 3.32Å; I343-V347 PolarHBondContact O-N 2.92Å; N344-V347 CarbonylContact O-C 3.59Å; N344-V347 WeakPolarHBondContact O-CA 3.42Å; N344-V347 WeakPolarHBondContact O-CB 3.11Å; N344-V347 PolarHBondContact O-N 2.85Å; V347-W349 PolarHBondContact O-N 2.79Å; V347-Y350 PolarHBondContact O-N 2.58Å; V347-V351 HydrophobicContact CG1-CG2 4.25Å; V347-V351 WeakPolarHBondContact O-CG2 3.45Å; V347-V351 PolarHBondContact O-N 3.49Å
348R98.9Very high98.8Very high10 Ų1032.2 Ų32.24%0.03819%0.189CC..Hα-helixtrans-65.7-38.5177.9-57.1-36.5-68-90.1-2.3112Y321 D328 N344 M345 D352 G353Y321-R348 PolarHBondContact OH-NE 3Å; Y321-R348 PolarHBondContact OH-NH2 3.18Å; D328-R348 WeakPolarHBondContact OD2-CD 3.33Å; D328-R348 WeakPolarHBondContact OD2-CG 3.33Å; D328-R348 IonicContact OD2-CZ 2.76Å; D328-R348 IonicContact OD2-NE 3.22Å; D328-R348 IonicContact OD2-NH1 3.62Å; D328-R348 PolarHBondContact OD2-NH1 2.91Å; N344-R348 VanDerWaalsContact O-CG 3.27Å; N344-R348 WeakPolarHBondContact O-CG 3.15Å; N344-R348 PolarHBondContact O-N 3.37Å; M345-R348 PolarHBondContact O-N 3.35Å; R348-D352 WeakPolarHBondContact CA-OD2 3.49Å; R348-D352 IonicContact CZ-OD1 2.81Å; R348-D352 IonicContact CZ-OD2 3.79Å; R348-D352 IonicContact NE-OD1 2.85Å; R348-D352 IonicContact NE-OD2 3.8Å; R348-D352 PolarHBondContact NE-OD2 3.47Å; R348-D352 IonicContact NH2-OD1 2.71Å; R348-D352 PolarHBondContact NH2-OD1 3.3Å; R348-D352 IonicContact NH2-OD2 2.89Å; R348-D352 PolarHBondContact NH2-OD2 3.23Å; R348-D352 WeakPolarHBondContact O-CA 3.46Å; R348-D352 VanDerWaalsContact O-CB 3.28Å; R348-D352 WeakPolarHBondContact O-CB 3.48Å; R348-D352 PolarHBondContact O-N 2.99Å; R348-G353 PolarHBondContact O-N 2.83Å
349W98.9Very high98.8Very high61 Ų6132.1 Ų32.123%0.23119%0.188CC..Hα-helixtrans-58.3-48.4170.3169.377.6000111.9I115 A116 M345 L346 V347 G353 F359I115-W349 HydrophobicContact CG2-CE3 4.26Å; I115-W349 HydrophobicContact CG2-CH2 3.55Å; I115-W349 HydrophobicContact CG2-CZ2 4.27Å; I115-W349 HydrophobicContact CG2-CZ3 3.54Å; A116-W349 HydrophobicContact CB-CB 4.16Å; A116-W349 HydrophobicContact CB-CD2 3.83Å; A116-W349 HydrophobicContact CB-CG 3.56Å; M345-W349 PolarHBondContact O-N 3.44Å; L346-W349 HydrophobicContact CD1-CE3 3.73Å; L346-W349 HydrophobicContact CD1-CZ3 4.11Å; L346-W349 WeakPolarHBondContact O-CB 3.31Å; L346-W349 PolarHBondContact O-N 3.34Å; V347-W349 PolarHBondContact O-N 2.79Å; W349-G353 WeakPolarHBondContact O-CA 3.06Å; W349-G353 PolarHBondContact O-N 2.93Å; W349-G353 VanDerWaalsContact O-N 3.1Å; W349-F359 HydrophobicContact CB-CD2 3.64Å; W349-F359 HydrophobicContact CB-CE2 3.5Å; W349-F359 VanDerWaalsContact CB-CE2 3.5Å; W349-F359 HydrophobicContact CB-CG 4.42Å; W349-F359 HydrophobicContact CB-CZ 4.12Å; W349-F359 AromaticContact CD1-CZ 3.93Å; W349-F359 HydrophobicContact CG-CE2 4.19Å; W349-F359 HydrophobicContact CG-CZ 4.34Å
350Y98.8Very high98.8Very high113 Ų11336 Ų3644%0.44321%0.205SC..Hα-helixtrans-66-40.1-176-179.3-98.8000112.8Y243 V247 L249 L346 V347Y243-Y350 HydrophobicContact CE1-CD1 4.12Å; V247-Y350 HydrophobicContact CB-CE1 4.3Å; V247-Y350 HydrophobicContact CG2-CD1 4.49Å; V247-Y350 HydrophobicContact CG2-CE1 3.92Å; L249-Y350 HydrophobicContact CD1-CD1 4.46Å; L249-Y350 HydrophobicContact CD1-CD2 3.82Å; L249-Y350 HydrophobicContact CD1-CG 3.76Å; L249-Y350 HydrophobicContact CG-CD2 4.03Å; L249-Y350 HydrophobicContact CG-CE2 4.41Å; L249-Y350 HydrophobicContact CG-CG 4.45Å; L346-Y350 WeakPolarHBondContact O-CB 3.32Å; L346-Y350 PolarHBondContact O-N 2.85Å; V347-Y350 PolarHBondContact O-N 2.58Å
351V98.8Very high98.8Very high59 Ų5939.4 Ų39.436%0.35822%0.221SC..Hα-helixtrans-92.2-51.3-174.6-177.30000112.8Y243 Y321 V347Y243-V351 HydrophobicContact CE1-CG2 4.08Å; Y243-V351 WeakPolarHBondContact OH-CG2 3.44Å; Y321-V351 HydrophobicContact CD1-CG1 4.48Å; Y321-V351 HydrophobicContact CD2-CB 4.48Å; Y321-V351 HydrophobicContact CD2-CG1 4.43Å; Y321-V351 HydrophobicContact CD2-CG2 4.13Å; Y321-V351 HydrophobicContact CE1-CG1 3.83Å; Y321-V351 HydrophobicContact CE2-CB 3.8Å; Y321-V351 HydrophobicContact CE2-CG1 3.8Å; Y321-V351 HydrophobicContact CE2-CG2 3.92Å; Y321-V351 VanDerWaalsContact CZ-CG1 3.48Å; V347-V351 HydrophobicContact CG1-CG2 4.25Å; V347-V351 WeakPolarHBondContact O-CG2 3.45Å; V347-V351 PolarHBondContact O-N 3.49Å
352D98.8Very high98.8Very high53 Ų5339.4 Ų39.428%0.28322%0.221SC..Hα-helixtrans-87.4-19.2-174-49.4-110.6000112Y321 R348 S356 V358Y321-D352 PolarHBondContact OH-OD1 3.47Å; Y321-D352 PolarHBondContact OH-OD2 3.19Å; R348-D352 WeakPolarHBondContact CA-OD2 3.49Å; R348-D352 IonicContact CZ-OD1 2.81Å; R348-D352 IonicContact CZ-OD2 3.79Å; R348-D352 IonicContact NE-OD1 2.85Å; R348-D352 IonicContact NE-OD2 3.8Å; R348-D352 PolarHBondContact NE-OD2 3.47Å; R348-D352 IonicContact NH2-OD1 2.71Å; R348-D352 PolarHBondContact NH2-OD1 3.3Å; R348-D352 IonicContact NH2-OD2 2.89Å; R348-D352 PolarHBondContact NH2-OD2 3.23Å; R348-D352 WeakPolarHBondContact O-CA 3.46Å; R348-D352 VanDerWaalsContact O-CB 3.28Å; R348-D352 WeakPolarHBondContact O-CB 3.48Å; R348-D352 PolarHBondContact O-N 2.99Å; D352-S356 WeakPolarHBondContact CB-OG 3.28Å; D352-S356 WeakPolarHBondContact O-CB 3.38Å; D352-V358 HydrophobicContact CB-CG1 4.04Å
353G98.5Very high98.8Very high17 Ų1741 Ų4118%0.17523%0.231CC..  trans85.7161.6-179.500000113.9R348 W349 T355 S356R348-G353 PolarHBondContact O-N 2.83Å; W349-G353 WeakPolarHBondContact O-CA 3.06Å; W349-G353 PolarHBondContact O-N 2.93Å; W349-G353 VanDerWaalsContact O-N 3.1Å; G353-T355 PolarHBondContact O-N 3.46Å; G353-S356 WeakPolarHBondContact O-CB 3.48Å; G353-S356 PolarHBondContact O-N 2.65Å; G353-S356 VanDerWaalsContact O-N 3.15Å; G353-S356 PolarHBondContact O-OG 2.99Å
354P98.2Very high98.8Very high66 Ų6643.7 Ų43.743%0.42925%0.25SC..THydrogen-bonded Turntrans-68.4-18.4-172.627.8-36.1000113.8F359 Q360P354-F359 HydrophobicContact CB-CD1 4.36Å; P354-F359 HydrophobicContact CB-CE1 4.18Å; P354-F359 VanDerWaalsContact O-CD1 3.32Å; P354-F359 WeakPolarHBondContact O-CD1 3.21Å; P354-Q360 PolarHBondContact O-NE2 2.86Å
355T98.1Very high98.7Very high131 Ų13144.5 Ų44.580%0.80425%0.253SS*.THydrogen-bonded Turntrans-93.6-2.5178.957.60000113.1G353G353-T355 PolarHBondContact O-N 3.46Å
356S98.8Very high98.7Very high21 Ų2144.7 Ų44.715%0.14725%0.253CS..SBendtrans-69.1143.618067.50000111.7D352 G353 V358 F359 Q360D352-S356 WeakPolarHBondContact CB-OG 3.28Å; D352-S356 WeakPolarHBondContact O-CB 3.38Å; G353-S356 WeakPolarHBondContact O-CB 3.48Å; G353-S356 PolarHBondContact O-N 2.65Å; G353-S356 VanDerWaalsContact O-N 3.15Å; G353-S356 PolarHBondContact O-OG 2.99Å; S356-V358 PolarHBondContact O-N 3.24Å; S356-F359 PolarHBondContact O-N 3.5Å; S356-F359 WeakPolarHBondContact OG-CB 3.35Å; S356-F359 PolarHBondContact OG-N 2.8Å; S356-Q360 WeakPolarHBondContact O-CG 3.49Å; S356-Q360 PolarHBondContact O-N 3.1Å
357A98.7Very high98.7Very high86 Ų8645.9 Ų45.971%0.71126%0.262SS*.Hα-helixtrans-58.9-36.4179.300000112.4Q360 E361A357-Q360 PolarHBondContact O-N 2.89Å; A357-E361 PolarHBondContact O-N 3.43Å
358V98.7Very high98.7Very high29 Ų2946.1 Ų46.118%0.17626%0.263CS..Hα-helixtrans-71.5-37.5-179.666.70000112.9D352 S356 E361 H362D352-V358 HydrophobicContact CB-CG1 4.04Å; S356-V358 PolarHBondContact O-N 3.24Å; V358-E361 PolarHBondContact O-N 3.35Å; V358-H362 PolarHBondContact O-N 3.44Å
359F98.9Very high98.7Very high6 Ų645.7 Ų45.73%0.02626%0.261CS..Hα-helixtrans-67.2-40.7172.4176.2-107.1000111A116 I118 M345 W349 P354 S356 E361 H362 V363A116-F359 HydrophobicContact CB-CE2 4.28Å; A116-F359 HydrophobicContact CB-CZ 3.95Å; I118-F359 HydrophobicContact CD1-CE2 4.14Å; I118-F359 HydrophobicContact CD1-CZ 3.84Å; I118-F359 HydrophobicContact CG1-CZ 3.78Å; M345-F359 HydrophobicContact CG-CD2 4.22Å; M345-F359 HydrophobicContact CG-CE2 3.85Å; W349-F359 HydrophobicContact CB-CD2 3.64Å; W349-F359 HydrophobicContact CB-CE2 3.5Å; W349-F359 VanDerWaalsContact CB-CE2 3.5Å; W349-F359 HydrophobicContact CB-CG 4.42Å; W349-F359 HydrophobicContact CB-CZ 4.12Å; W349-F359 AromaticContact CD1-CZ 3.93Å; W349-F359 HydrophobicContact CG-CE2 4.19Å; W349-F359 HydrophobicContact CG-CZ 4.34Å; P354-F359 HydrophobicContact CB-CD1 4.36Å; P354-F359 HydrophobicContact CB-CE1 4.18Å; P354-F359 VanDerWaalsContact O-CD1 3.32Å; P354-F359 WeakPolarHBondContact O-CD1 3.21Å; S356-F359 PolarHBondContact O-N 3.5Å; S356-F359 WeakPolarHBondContact OG-CB 3.35Å; S356-F359 PolarHBondContact OG-N 2.8Å; F359-E361 VanDerWaalsContact C-N 3.31Å; F359-E361 PolarHBondContact O-N 3.3Å; F359-H362 VanDerWaalsContact O-CB 3.3Å; F359-H362 WeakPolarHBondContact O-CB 3.34Å; F359-H362 PolarHBondContact O-N 3.49Å; F359-H362 VanDerWaalsContact O-N 3.17Å; F359-V363 HydrophobicContact CD1-CG2 4.22Å; F359-V363 HydrophobicContact CE1-CG2 3.77Å; F359-V363 HydrophobicContact CE2-CG2 4.03Å; F359-V363 HydrophobicContact CZ-CG2 3.67Å; F359-V363 WeakPolarHBondContact O-CG2 3.22Å; F359-V363 PolarHBondContact O-N 3.16Å
360Q98.8Very high98.7Very high100 Ų10043 Ų4347%0.46725%0.251SS..Hα-helixtrans-63.3-36.7174.9-66.5-62-31.900112.3P354 S356 A357 V363 S364P354-Q360 PolarHBondContact O-NE2 2.86Å; S356-Q360 WeakPolarHBondContact O-CG 3.49Å; S356-Q360 PolarHBondContact O-N 3.1Å; A357-Q360 PolarHBondContact O-N 2.89Å; Q360-V363 PolarHBondContact O-N 3.5Å; Q360-S364 WeakPolarHBondContact O-CB 3.24Å; Q360-S364 PolarHBondContact O-N 2.99Å
361E98.9Very high98.8Very high75 Ų7537.9 Ų37.935%0.3523%0.231SC..Hα-helixtrans-62.7-45.5171.6-171.6174.9-171.700111C333 A357 V358 F359 V363 S364 R365C333-E361 HydrophobicContact CB-CG 4.09Å; A357-E361 PolarHBondContact O-N 3.43Å; V358-E361 PolarHBondContact O-N 3.35Å; F359-E361 VanDerWaalsContact C-N 3.31Å; F359-E361 PolarHBondContact O-N 3.3Å; E361-V363 PolarHBondContact O-N 2.91Å; E361-S364 WeakPolarHBondContact O-CB 3.35Å; E361-S364 PolarHBondContact O-N 3.45Å; E361-S364 VanDerWaalsContact O-N 3.14Å; E361-S364 PolarHBondContact O-OG 3.11Å; E361-R365 WeakPolarHBondContact O-CG 3.47Å; E361-R365 PolarHBondContact O-N 3.25Å; E361-R365 VanDerWaalsContact O-N 3.13Å
362H98.9Very high98.8Very high0 Ų035 Ų350%021%0.214CC..Hα-helixtrans-55.7-46.5173-99.1-68.9000113D328 C333 K341 M345 V358 F359 S364 R365 I366D328-H362 IonicContact OD1-CE1 2.73Å; D328-H362 PolarHBondContact OD1-CE1 3.5Å; D328-H362 VanDerWaalsContact OD1-CE1 3.3Å; D328-H362 IonicContact OD1-NE2 3.74Å; D328-H362 PolarHBondContact OD1-NE2 3.09Å; D328-H362 IonicContact OD2-CD2 3.99Å; D328-H362 IonicContact OD2-NE2 3.85Å; D328-H362 PolarHBondContact OD2-NE2 3.27Å; C333-H362 HydrophobicContact CB-CB 4.32Å; C333-H362 VanDerWaalsContact SG-CD2 3.59Å; K341-H362 PolarHBondContact NZ-ND1 2.99Å; K341-H362 PolarHBondContact NZ-O 3.5Å; M345-H362 HydrophobicContact CB-CB 3.95Å; M345-H362 HydrophobicContact CG-CB 3.72Å; M345-H362 HydrophobicContact SD-CB 3.98Å; V358-H362 PolarHBondContact O-N 3.44Å; F359-H362 VanDerWaalsContact O-CB 3.3Å; F359-H362 WeakPolarHBondContact O-CB 3.34Å; F359-H362 PolarHBondContact O-N 3.49Å; F359-H362 VanDerWaalsContact O-N 3.17Å; H362-S364 VanDerWaalsContact C-N 3.32Å; H362-R365 PolarHBondContact O-N 3.33Å; H362-R365 VanDerWaalsContact O-N 3.15Å; H362-I366 PolarHBondContact O-N 3.22Å
363V98.9Very high98.7Very high34 Ų3432.6 Ų32.621%0.20620%0.202CC..Hα-helixtrans-61.4-43.3176.31730000110.5I118 F359 Q360 E361 R365 I366I118-V363 HydrophobicContact CD1-CG2 4.03Å; I118-V363 HydrophobicContact CG1-CG2 4.16Å; I118-V363 HydrophobicContact CG2-CG1 4.01Å; I118-V363 HydrophobicContact CG2-CG2 4.29Å; F359-V363 HydrophobicContact CD1-CG2 4.22Å; F359-V363 HydrophobicContact CE1-CG2 3.77Å; F359-V363 HydrophobicContact CE2-CG2 4.03Å; F359-V363 HydrophobicContact CZ-CG2 3.67Å; F359-V363 WeakPolarHBondContact O-CG2 3.22Å; F359-V363 PolarHBondContact O-N 3.16Å; Q360-V363 PolarHBondContact O-N 3.5Å; E361-V363 PolarHBondContact O-N 2.91Å; V363-R365 PolarHBondContact O-N 2.86Å; V363-R365 VanDerWaalsContact O-N 3.09Å; V363-I366 HydrophobicContact CG1-CD1 4.38Å; V363-I366 WeakPolarHBondContact O-CB 3.31Å; V363-I366 WeakPolarHBondContact O-CG1 3.48Å; V363-I366 PolarHBondContact O-N 3.46Å; V363-I366 VanDerWaalsContact O-N 3.1Å
364S98.7Very high98.7Very high57 Ų5733.9 Ų33.940%0.39920%0.204SC..Hα-helixtrans-63-17.1177.885.20000114R33 Q360 E361 H362 P367R33-S364 PolarHBondContact NH2-O 2.92Å; Q360-S364 WeakPolarHBondContact O-CB 3.24Å; Q360-S364 PolarHBondContact O-N 2.99Å; E361-S364 WeakPolarHBondContact O-CB 3.35Å; E361-S364 PolarHBondContact O-N 3.45Å; E361-S364 VanDerWaalsContact O-N 3.14Å; E361-S364 PolarHBondContact O-OG 3.11Å; H362-S364 VanDerWaalsContact C-N 3.32Å; S364-P367 WeakPolarHBondContact O-CD 3.31Å
365R98.8Very high98.8Very high16 Ų1631 Ų316%0.0619%0.185CC..THydrogen-bonded Turntrans-98.5-2.9177.9-67.2-64.3-168.2175.70.6114.7K332 C333 I334 E361 H362 V363 D368 D449K332-R365 WeakPolarHBondContact O-CG 3.26Å; K332-R365 PolarHBondContact O-NE 2.89Å; K332-R365 VanDerWaalsContact O-NE 3.08Å; C333-R365 HydrophobicContact CB-CG 4.34Å; I334-R365 HydrophobicContact CG1-CG 4.22Å; E361-R365 WeakPolarHBondContact O-CG 3.47Å; E361-R365 PolarHBondContact O-N 3.25Å; E361-R365 VanDerWaalsContact O-N 3.13Å; H362-R365 PolarHBondContact O-N 3.33Å; H362-R365 VanDerWaalsContact O-N 3.15Å; V363-R365 PolarHBondContact O-N 2.86Å; V363-R365 VanDerWaalsContact O-N 3.09Å; R365-D368 WeakPolarHBondContact CA-OD1 3.42Å; R365-D368 VanDerWaalsContact CD-OD2 3.3Å; R365-D368 WeakPolarHBondContact CD-OD2 3.14Å; R365-D368 IonicContact CZ-OD2 3.57Å; R365-D368 IonicContact NH1-OD2 3.48Å; R365-D368 PolarHBondContact NH1-OD2 3.41Å; R365-D368 WeakPolarHBondContact O-CB 3.35Å; R365-D368 PolarHBondContact O-N 3.47Å; R365-D449 IonicContact CZ-OD2 3.9Å; R365-D449 IonicContact NH1-OD2 2.84Å; R365-D449 IonicContact NH2-OD2 3.31Å; R365-D449 PolarHBondContact NH2-OD2 3.44Å
366I98.9Very high98.8Very high4 Ų424.8 Ų24.82%0.02115%0.147CC..SBendtrans-57.4-45.2169-63.3170.3000112L109 I118 M345 H362 V363 D368 Y369 L370L109-I366 HydrophobicContact CD1-CD1 4.27Å; L109-I366 HydrophobicContact CD1-CG1 4.17Å; L109-I366 HydrophobicContact CD1-CG2 3.99Å; L109-I366 HydrophobicContact CD2-CG2 4Å; I118-I366 HydrophobicContact CD1-CD1 4.23Å; I118-I366 HydrophobicContact CG2-CD1 3.95Å; M345-I366 HydrophobicContact CE-CD1 3.8Å; M345-I366 HydrophobicContact CE-CG1 3.97Å; M345-I366 HydrophobicContact SD-CD1 3.81Å; M345-I366 HydrophobicContact SD-CG1 3.86Å; H362-I366 PolarHBondContact O-N 3.22Å; V363-I366 HydrophobicContact CG1-CD1 4.38Å; V363-I366 WeakPolarHBondContact O-CB 3.31Å; V363-I366 WeakPolarHBondContact O-CG1 3.48Å; V363-I366 PolarHBondContact O-N 3.46Å; V363-I366 VanDerWaalsContact O-N 3.1Å; I366-D368 PolarHBondContact O-N 3.04Å; I366-D368 VanDerWaalsContact O-N 3.16Å; I366-Y369 PolarHBondContact O-N 3.23Å; I366-Y369 VanDerWaalsContact O-N 3.08Å; I366-L370 HydrophobicContact CG2-CD1 3.79Å; I366-L370 HydrophobicContact CG2-CG 4.39Å
367P98.9Very high98.8Very high26 Ų2623.8 Ų23.817%0.16914%0.14CC..G310 helixtrans-56.8-31.9-179.9-22.933.2000113.7T35 W124 S364 Y369 L370T35-P367 HydrophobicContact CG2-CB 3.68Å; W124-P367 HydrophobicContact CH2-CB 3.66Å; W124-P367 HydrophobicContact CH2-CG 3.67Å; W124-P367 HydrophobicContact CZ3-CB 4.35Å; W124-P367 HydrophobicContact CZ3-CG 4.21Å; S364-P367 WeakPolarHBondContact O-CD 3.31Å; P367-Y369 PolarHBondContact O-N 2.9Å; P367-Y369 VanDerWaalsContact O-N 3.14Å; P367-L370 PolarHBondContact O-N 2.8Å; P367-L370 VanDerWaalsContact O-N 3.12Å
368D98.9Very high98.8Very high5 Ų519.9 Ų19.93%0.02711%0.107CC..G310 helixtrans-62.1-19.6-179.4-56.142.3000112.7R33 R365 I366 N383R33-D368 WeakPolarHBondContact CD-OD2 3.22Å; R33-D368 WeakPolarHBondContact CG-OD2 3.42Å; R33-D368 IonicContact CZ-OD1 2.64Å; R33-D368 VanDerWaalsContact CZ-OD1 3.29Å; R33-D368 IonicContact CZ-OD2 2.7Å; R33-D368 IonicContact NE-OD1 2.64Å; R33-D368 PolarHBondContact NE-OD1 3.22Å; R33-D368 IonicContact NE-OD2 3.99Å; R33-D368 PolarHBondContact NE-OD2 2.85Å; R33-D368 IonicContact NH2-OD1 2.96Å; R33-D368 PolarHBondContact NH2-OD1 3.13Å; R33-D368 IonicContact NH2-OD2 3.67Å; R365-D368 WeakPolarHBondContact CA-OD1 3.42Å; R365-D368 VanDerWaalsContact CD-OD2 3.3Å; R365-D368 WeakPolarHBondContact CD-OD2 3.14Å; R365-D368 IonicContact CZ-OD2 3.57Å; R365-D368 IonicContact NH1-OD2 3.48Å; R365-D368 PolarHBondContact NH1-OD2 3.41Å; R365-D368 WeakPolarHBondContact O-CB 3.35Å; R365-D368 PolarHBondContact O-N 3.47Å; I366-D368 PolarHBondContact O-N 3.04Å; I366-D368 VanDerWaalsContact O-N 3.16Å; D368-N383 HydrophobicContact CB-CB 4.37Å; D368-N383 WeakPolarHBondContact O-CA 3.45Å
369Y98.9Very high98.8Very high1 Ų118.8 Ų18.80%0.00410%0.1CC..G310 helixtrans-106.6-0.4-179.5-79.6-81.7000113.2I334 G337 P338 K341 I366 P367 M379 Q380 T382 N383I334-Y369 HydrophobicContact CG2-CE2 4Å; I334-Y369 WeakPolarHBondContact CG2-OH 3.48Å; I334-Y369 WeakPolarHBondContact O-CE2 3.47Å; I334-Y369 PolarHBondContact O-OH 3.04Å; G337-Y369 VanDerWaalsContact C-OH 3.3Å; G337-Y369 WeakPolarHBondContact CA-OH 3.08Å; G337-Y369 PolarHBondContact O-OH 3.05Å; P338-Y369 HydrophobicContact CB-CD1 3.72Å; P338-Y369 HydrophobicContact CB-CE1 3.79Å; P338-Y369 HydrophobicContact CG-CE1 4.33Å; K341-Y369 HydrophobicContact CB-CE2 4.16Å; K341-Y369 HydrophobicContact CD-CD2 4.14Å; K341-Y369 HydrophobicContact CD-CE2 4.09Å; K341-Y369 HydrophobicContact CG-CD2 4.37Å; K341-Y369 HydrophobicContact CG-CE2 3.81Å; I366-Y369 PolarHBondContact O-N 3.23Å; I366-Y369 VanDerWaalsContact O-N 3.08Å; P367-Y369 PolarHBondContact O-N 2.9Å; P367-Y369 VanDerWaalsContact O-N 3.14Å; Y369-M379 HydrophobicContact CD1-CE 4.45Å; Y369-M379 HydrophobicContact CG-CE 4.17Å; Y369-M379 CarbonylContact O-C 3.57Å; Y369-M379 VanDerWaalsContact O-CA 3.26Å; Y369-M379 WeakPolarHBondContact O-CA 3.07Å; Y369-Q380 PolarHBondContact O-N 3.12Å; Y369-T382 WeakPolarHBondContact CD1-O 3.35Å; Y369-N383 HydrophobicContact CE1-CB 4.15Å; Y369-N383 VanDerWaalsContact CE1-N 3.26Å; Y369-N383 HydrophobicContact CE2-CB 4.18Å
370L98.9Very high98.8Very high5 Ų518.6 Ų18.63%0.02610%0.099CC..EExtended strand (participates in β ladder)trans-109.6123.2-175.7-66.2177.2000111.1L106 L109 W124 M128 I366 P367 M377 K378 M379L106-L370 HydrophobicContact CD1-CD2 4.27Å; L109-L370 HydrophobicContact CD2-CD1 4.43Å; L109-L370 HydrophobicContact CD2-CD2 3.88Å; L109-L370 HydrophobicContact CD2-CG 4.44Å; W124-L370 HydrophobicContact CE3-CD1 3.55Å; W124-L370 HydrophobicContact CZ3-CD1 3.55Å; M128-L370 HydrophobicContact CE-CD1 3.39Å; M128-L370 HydrophobicContact CE-CD2 3.75Å; M128-L370 HydrophobicContact CE-CG 4.2Å; I366-L370 HydrophobicContact CG2-CD1 3.79Å; I366-L370 HydrophobicContact CG2-CG 4.39Å; P367-L370 PolarHBondContact O-N 2.8Å; P367-L370 VanDerWaalsContact O-N 3.12Å; L370-M377 HydrophobicContact CB-CG 4.27Å; L370-M377 HydrophobicContact CB-SD 4.1Å; L370-M377 HydrophobicContact CD1-SD 4.14Å; L370-K378 WeakPolarHBondContact CA-O 3.43Å; L370-M379 HydrophobicContact CD2-CB 4.25Å; L370-M379 HydrophobicContact CD2-CG 4.39Å
371W98.9Very high98.8Very high4 Ų414.6 Ų14.62%0.0158%0.084CC..EExtended strand (participates in β ladder)trans-120.9129.8-178.5-178.3-93.2000111.1L27 W36 A96 M377 K378 Q380L27-W371 HydrophobicContact CD1-CZ3 4.09Å; L27-W371 HydrophobicContact CD2-CH2 3.94Å; L27-W371 HydrophobicContact CD2-CZ3 4.05Å; W36-W371 HydrophobicContact CZ2-CH2 4.18Å; W36-W371 HydrophobicContact CZ2-CZ2 4.17Å; W36-W371 HydrophobicContact CZ2-CZ3 4.49Å; W36-W371 AromaticContact NE1-CD2 3.53Å; W36-W371 AromaticContact NE1-CE3 3.29Å; W36-W371 VanDerWaalsContact NE1-CE3 3.29Å; W36-W371 AromaticContact NE1-CZ3 3.6Å; A96-W371 HydrophobicContact CB-CH2 3.96Å; A96-W371 HydrophobicContact CB-CZ3 4.17Å; W371-M377 CarbonylContact O-C 3.56Å; W371-M377 VanDerWaalsContact O-CA 3.31Å; W371-M377 WeakPolarHBondContact O-CA 3.41Å; W371-K378 PolarHBondContact N-O 2.73Å; W371-K378 PolarHBondContact O-N 3.16Å; W371-Q380 HydrophobicContact CB-CG 3.71Å
372L98.8Very high98.8Very high0 Ų011.5 Ų11.50%07%0.071CC..EExtended strand (participates in β ladder)trans-90.2104.6171.1-174.161.4000109.6W25 W36 L57 E127 M377W25-L372 HydrophobicContact CB-CD2 3.95Å; W25-L372 HydrophobicContact CD2-CD2 3.21Å; W25-L372 HydrophobicContact CE3-CD2 3.73Å; W25-L372 HydrophobicContact CG-CD2 3.32Å; W25-L372 HydrophobicContact CH2-CD2 4.37Å; W25-L372 HydrophobicContact CZ2-CD2 4Å; W25-L372 HydrophobicContact CZ3-CD2 4.27Å; W36-L372 HydrophobicContact CD2-CB 3.93Å; W36-L372 HydrophobicContact CE3-CB 4.39Å; W36-L372 HydrophobicContact CG-CB 4.07Å; L57-L372 HydrophobicContact CD2-CB 4.03Å; L57-L372 HydrophobicContact CD2-CD2 3.37Å; L57-L372 HydrophobicContact CD2-CG 3.39Å; E127-L372 HydrophobicContact CB-CD1 3.83Å; E127-L372 HydrophobicContact CG-CD1 3.78Å; L372-M377 HydrophobicContact CD1-CB 4.14Å
373G98.4Very high98.8Very high2 Ų211.7 Ų11.72%0.0217%0.072CC..EExtended strand (participates in β ladder)trans-103-168.3177.800000113.1S56 D375 G376S56-G373 CarbonylContact O-C 3.58Å; G373-D375 PolarHBondContact O-N 3.18Å; G373-G376 PolarHBondContact N-O 3.07Å; G373-G376 PolarHBondContact O-N 3.49Å
374L98.8Very high98.8Very high44 Ų4410 Ų1023%0.236%0.062CC..THydrogen-bonded Turntrans-61.1-27.8-177.1-55.6-177.3000113.8P13 Y14 K15 T16 R130P13-L374 HydrophobicContact CB-CB 4.4Å; P13-L374 HydrophobicContact CG-CD1 4.38Å; Y14-L374 CarbonylContact O-C 3.58Å; K15-L374 WeakPolarHBondContact CA-O 3.36Å; T16-L374 PolarHBondContact N-O 3.47Å; R130-L374 PolarHBondContact NH2-O 3.14Å
375D98.7Very high98.8Very high6 Ų67.4 Ų7.43%0.0324%0.044CC..THydrogen-bonded Turntrans-106.2-2.2-173.947.24.4000113.7P13 Y14 Y131 S134 G373 K378P13-D375 VanDerWaalsContact CB-OD2 3.32Å; P13-D375 WeakPolarHBondContact CB-OD2 3.33Å; Y14-D375 WeakPolarHBondContact O-CB 3.31Å; Y131-D375 VanDerWaalsContact CA-O 3.25Å; Y131-D375 WeakPolarHBondContact CA-O 3.47Å; Y131-D375 HydrophobicContact CD2-CB 4.49Å; Y131-D375 PolarHBondContact N-O 3.14Å; S134-D375 WeakPolarHBondContact CB-O 3.48Å; S134-D375 PolarHBondContact OG-O 3Å; G373-D375 PolarHBondContact O-N 3.18Å; D375-K378 WeakPolarHBondContact OD1-CE 3.47Å; D375-K378 IonicContact OD1-NZ 2.76Å; D375-K378 PolarHBondContact OD1-NZ 2.84Å; D375-K378 IonicContact OD2-NZ 3.69Å; D375-K378 PolarHBondContact OD2-NZ 2.67Å
376G98.8Very high98.8Very high0 Ų06.7 Ų6.70%04%0.041CC..EExtended strand (participates in β ladder)trans126-168.3-178.700000113.5G373G373-G376 PolarHBondContact N-O 3.07Å; G373-G376 PolarHBondContact O-N 3.49Å
377M98.9Very high98.8Very high0 Ų06.5 Ų6.50%04%0.04CC..EExtended strand (participates in β ladder)trans-87.4118.8-178.1-177.8172.3-76.800111.4W25 W124 E127 M128 Y131 L370 W371 L372W25-M377 HydrophobicContact CH2-CE 3.45Å; W25-M377 VanDerWaalsContact CH2-CE 3.45Å; W25-M377 HydrophobicContact CZ3-CE 3.58Å; W124-M377 HydrophobicContact CB-CE 4.29Å; W124-M377 HydrophobicContact CB-SD 3.73Å; W124-M377 HydrophobicContact CD2-CE 4.08Å; W124-M377 HydrophobicContact CD2-SD 4.02Å; W124-M377 HydrophobicContact CE3-SD 4.27Å; W124-M377 HydrophobicContact CG-CE 3.87Å; W124-M377 HydrophobicContact CG-SD 3.83Å; E127-M377 HydrophobicContact CB-CB 3.64Å; E127-M377 PolarHBondContact O-N 2.78Å; M128-M377 HydrophobicContact CE-CG 4.31Å; M128-M377 HydrophobicContact CE-SD 3.72Å; M128-M377 HydrophobicContact CG-CB 4.13Å; M128-M377 HydrophobicContact CG-CG 4.11Å; M128-M377 HydrophobicContact CG-SD 4.29Å; Y131-M377 VanDerWaalsContact CB-O 3.29Å; Y131-M377 WeakPolarHBondContact CB-O 3.46Å; L370-M377 HydrophobicContact CB-CG 4.27Å; L370-M377 HydrophobicContact CB-SD 4.1Å; L370-M377 HydrophobicContact CD1-SD 4.14Å; W371-M377 CarbonylContact O-C 3.56Å; W371-M377 VanDerWaalsContact O-CA 3.31Å; W371-M377 WeakPolarHBondContact O-CA 3.41Å; L372-M377 HydrophobicContact CD1-CB 4.14Å
378K98.9Very high98.8Very high3 Ų35.6 Ų5.61%0.0133%0.033CC..EExtended strand (participates in β ladder)trans-119167.6178.769.4-166.369.5173.80111.9D98 Y131 L370 W371 D375D98-K378 WeakPolarHBondContact OD1-CD 3.43Å; D98-K378 IonicContact OD1-NZ 2.99Å; D98-K378 WeakPolarHBondContact OD2-CD 3.49Å; D98-K378 VanDerWaalsContact OD2-CE 3.24Å; D98-K378 WeakPolarHBondContact OD2-CE 3.17Å; D98-K378 IonicContact OD2-NZ 3.75Å; D98-K378 PolarHBondContact OD2-NZ 2.78Å; Y131-K378 HydrophobicContact CD1-CB 3.8Å; Y131-K378 HydrophobicContact CD2-CB 3.92Å; Y131-K378 HydrophobicContact CE1-CB 3.57Å; Y131-K378 HydrophobicContact CE2-CB 3.72Å; Y131-K378 HydrophobicContact CE2-CD 4.07Å; Y131-K378 VanDerWaalsContact CE2-CE 3.5Å; Y131-K378 HydrophobicContact CG-CB 3.96Å; L370-K378 WeakPolarHBondContact CA-O 3.43Å; W371-K378 PolarHBondContact N-O 2.73Å; W371-K378 PolarHBondContact O-N 3.16Å; D375-K378 WeakPolarHBondContact OD1-CE 3.47Å; D375-K378 IonicContact OD1-NZ 2.76Å; D375-K378 PolarHBondContact OD1-NZ 2.84Å; D375-K378 IonicContact OD2-NZ 3.69Å; D375-K378 PolarHBondContact OD2-NZ 2.67Å
379M98.9Very high98.8Very high6 Ų65.5 Ų5.53%0.033%0.032CC..EExtended strand (participates in β ladder)trans-95.7127.7171.9-163.6177.1-169.400110.1L105 L106 L109 P338 Y369 L370L105-M379 HydrophobicContact CB-CB 3.97Å; L105-M379 HydrophobicContact CB-CG 4.15Å; L105-M379 HydrophobicContact CB-SD 3.89Å; L106-M379 HydrophobicContact CB-CB 4.18Å; L106-M379 HydrophobicContact CD1-CB 4.37Å; L109-M379 HydrophobicContact CB-CE 4.25Å; L109-M379 HydrophobicContact CB-SD 3.88Å; L109-M379 HydrophobicContact CD2-CE 4.29Å; L109-M379 HydrophobicContact CD2-SD 4.14Å; P338-M379 HydrophobicContact CB-CE 3.5Å; P338-M379 VanDerWaalsContact CB-CE 3.5Å; P338-M379 HydrophobicContact CB-CG 4.38Å; P338-M379 HydrophobicContact CB-SD 4.08Å; Y369-M379 HydrophobicContact CD1-CE 4.45Å; Y369-M379 HydrophobicContact CG-CE 4.17Å; Y369-M379 CarbonylContact O-C 3.57Å; Y369-M379 VanDerWaalsContact O-CA 3.26Å; Y369-M379 WeakPolarHBondContact O-CA 3.07Å; L370-M379 HydrophobicContact CD2-CB 4.25Å; L370-M379 HydrophobicContact CD2-CG 4.39Å
380Q98.8Very high98.8Very high3 Ų35.4 Ų5.41%0.0143%0.032CC..  trans-73149.1-179.3-58.3-77.673.800110.9G97 Y99 P338 Y369 W371 T382G97-Q380 PolarHBondContact O-NE2 2.97Å; Y99-Q380 VanDerWaalsContact C-OE1 3.28Å; P338-Q380 WeakPolarHBondContact CG-O 3.31Å; Y369-Q380 PolarHBondContact O-N 3.12Å; W371-Q380 HydrophobicContact CB-CG 3.71Å; Q380-T382 VanDerWaalsContact C-N 3.26Å; Q380-T382 CarbonylContact C-O 3.31Å; Q380-T382 WeakPolarHBondContact CB-O 3.36Å; Q380-T382 PolarHBondContact O-N 3.38Å
381G98.4Very high98.8Very high15 Ų155.2 Ų5.216%0.1553%0.031CC..SBendtrans-71.5-14.8179.500000115.4Y99 P338Y99-G381 PolarHBondContact O-N 3.02Å; P338-G381 WeakPolarHBondContact CD-O 3.37Å
382T98.8Very high98.8Very high11 Ų115.1 Ų5.17%0.0673%0.031CC..SBendtrans-144.3-176.9167.150.80000106.4Y99 Y369 Q380 G384 F445Y99-T382 VanDerWaalsContact CD1-OG1 3.22Å; Y99-T382 WeakPolarHBondContact CD1-OG1 3.2Å; Y99-T382 HydrophobicContact CE1-CG2 4.07Å; Y99-T382 WeakPolarHBondContact CE1-OG1 3.28Å; Y369-T382 WeakPolarHBondContact CD1-O 3.35Å; Q380-T382 VanDerWaalsContact C-N 3.26Å; Q380-T382 CarbonylContact C-O 3.31Å; Q380-T382 WeakPolarHBondContact CB-O 3.36Å; Q380-T382 PolarHBondContact O-N 3.38Å; T382-G384 PolarHBondContact O-N 3.43Å; T382-G384 PolarHBondContact OG1-N 2.88Å; T382-G384 PolarHBondContact OG1-O 3.42Å; T382-F445 HydrophobicContact CG2-CD1 4.16Å; T382-F445 HydrophobicContact CG2-CE1 4.45Å
383N98.8Very high98.8Very high3 Ų35.1 Ų5.12%0.0163%0.031CC..SBendtrans-72.524.5170.671.5-62.5000113.5I334 D368 Y369 Q386 S446 T447I334-N383 HydrophobicContact CG2-CB 3.94Å; D368-N383 HydrophobicContact CB-CB 4.37Å; D368-N383 WeakPolarHBondContact O-CA 3.45Å; Y369-N383 HydrophobicContact CE1-CB 4.15Å; Y369-N383 VanDerWaalsContact CE1-N 3.26Å; Y369-N383 HydrophobicContact CE2-CB 4.18Å; N383-Q386 PolarHBondContact O-NE2 2.8Å; N383-S446 WeakPolarHBondContact OD1-CB 3.41Å; N383-S446 PolarHBondContact OD1-OG 2.96Å; N383-T447 PolarHBondContact ND2-OG1 3.08Å
384G98.6Very high98.8Very high0 Ų05.1 Ų5.10%03%0.03CC..  trans119174-176.400000114T382 Q386 F445 S446T382-G384 PolarHBondContact O-N 3.43Å; T382-G384 PolarHBondContact OG1-N 2.88Å; T382-G384 PolarHBondContact OG1-O 3.42Å; G384-Q386 PolarHBondContact O-OE1 3.15Å; G384-F445 WeakPolarHBondContact O-CD1 3.44Å; G384-F445 WeakPolarHBondContact O-CE1 3.39Å; G384-S446 WeakPolarHBondContact O-CB 3.07Å
385S98.8Very high98.8Very high2 Ų23.3 Ų3.31%0.0142%0.021CC..  trans-113.430.6178.149.90000112.7L387 W388 D389 F445S385-L387 PolarHBondContact O-N 3.34Å; S385-W388 PolarHBondContact O-N 2.97Å; S385-D389 WeakPolarHBondContact CB-OD2 3.42Å; S385-D389 WeakPolarHBondContact O-CB 3.31Å; S385-D389 PolarHBondContact O-N 3.42Å; S385-D389 PolarHBondContact OG-OD2 3.2Å; S385-F445 VanDerWaalsContact CA-CE1 3.47Å
386Q98.9Very high98.8Very high0 Ų03 Ų30%02%0.019CC..Hα-helixtrans-60.6-52.9-162.7-58.891.3-32.300113.8G32 Q34 H94 N383 G384 T390 F418 S446 T447G32-Q386 WeakPolarHBondContact O-CG 3.46Å; G32-Q386 PolarHBondContact O-NE2 3.42Å; Q34-Q386 VanDerWaalsContact NE2-CG 3.3Å; H94-Q386 HydrophobicContact CB-CB 4.49Å; H94-Q386 WeakPolarHBondContact CD2-CG 2.99Å; N383-Q386 PolarHBondContact O-NE2 2.8Å; G384-Q386 PolarHBondContact O-OE1 3.15Å; Q386-T390 VanDerWaalsContact O-CB 3.25Å; Q386-T390 WeakPolarHBondContact O-CB 3.16Å; Q386-T390 PolarHBondContact O-N 2.82Å; Q386-T390 VanDerWaalsContact O-N 3.11Å; Q386-T390 PolarHBondContact O-OG1 2.83Å; Q386-F418 HydrophobicContact CB-CE1 4.39Å; Q386-F418 HydrophobicContact CB-CZ 3.78Å; Q386-S446 VanDerWaalsContact OE1-CA 3.23Å; Q386-S446 VanDerWaalsContact OE1-CB 3.24Å; Q386-T447 HydrophobicContact CB-CG2 4.44Å; Q386-T447 VanDerWaalsContact CD-CG2 3.45Å; Q386-T447 HydrophobicContact CG-CG2 4.12Å; Q386-T447 VanDerWaalsContact NE2-CG2 3.27Å
387L98.9Very high98.8Very high0 Ų03 Ų30%02%0.019CC..Hα-helixtrans-63.8-48.6177.7-175.4110.4000110.6S385 D389 T390 C391 L419 T422 F443 P444 F445 S446 C457S385-L387 PolarHBondContact O-N 3.34Å; L387-D389 PolarHBondContact O-N 3.23Å; L387-T390 PolarHBondContact O-N 3.47Å; L387-C391 WeakPolarHBondContact O-CB 3.32Å; L387-C391 PolarHBondContact O-N 2.86Å; L387-C391 PolarHBondContact O-SG 3.21Å; L387-L419 HydrophobicContact CD1-CD2 3.89Å; L387-L419 HydrophobicContact CG-CD2 4.4Å; L387-T422 HydrophobicContact CB-CG2 4.31Å; L387-T422 HydrophobicContact CD1-CG2 3.41Å; L387-T422 VanDerWaalsContact CD1-CG2 3.41Å; L387-T422 HydrophobicContact CG-CG2 4.47Å; L387-F443 HydrophobicContact CD1-CB 3.85Å; L387-F443 HydrophobicContact CD1-CD1 3.34Å; L387-F443 HydrophobicContact CD1-CE1 4.16Å; L387-F443 HydrophobicContact CD1-CG 3.99Å; L387-F443 HydrophobicContact CD2-CB 3.61Å; L387-F443 HydrophobicContact CD2-CG 4.41Å; L387-F443 HydrophobicContact CG-CB 4.37Å; L387-P444 WeakPolarHBondContact CB-O 3.27Å; L387-P444 WeakPolarHBondContact CD2-O 3.48Å; L387-F445 PolarHBondContact N-O 3.15Å; L387-S446 WeakPolarHBondContact CB-O 3.36Å; L387-S446 PolarHBondContact N-O 2.81Å; L387-S446 VanDerWaalsContact N-O 3.12Å; L387-C457 HydrophobicContact CD2-CB 3.83Å; L387-C457 WeakPolarHBondContact CD2-O 3.42Å
388W98.9Very high98.8Very high8 Ų83.3 Ų3.33%0.032%0.021CC..Hα-helixtrans-53.9-54.1-177.8-177.8-101.8000112.4S385 T390 C391 F392 F445 D456 Y705 Y708S385-W388 PolarHBondContact O-N 2.97Å; W388-T390 VanDerWaalsContact C-N 3.34Å; W388-T390 PolarHBondContact O-N 3.07Å; W388-C391 PolarHBondContact O-N 2.84Å; W388-F392 HydrophobicContact CD2-CD2 4.49Å; W388-F392 HydrophobicContact CD2-CE2 4.12Å; W388-F392 AromaticContact CE2-CD2 3.93Å; W388-F392 AromaticContact CE2-CE2 3.32Å; W388-F392 AromaticContact CH2-CE2 3.84Å; W388-F392 HydrophobicContact CH2-CE2 3.84Å; W388-F392 AromaticContact CH2-CZ 3.68Å; W388-F392 HydrophobicContact CH2-CZ 3.68Å; W388-F392 HydrophobicContact CZ2-CD2 4.23Å; W388-F392 AromaticContact CZ2-CE2 3.19Å; W388-F392 HydrophobicContact CZ2-CE2 3.19Å; W388-F392 AromaticContact CZ2-CZ 3.54Å; W388-F392 HydrophobicContact CZ2-CZ 3.54Å; W388-F392 HydrophobicContact CZ3-CZ 4.3Å; W388-F392 AromaticContact NE1-CD2 3.84Å; W388-F392 AromaticContact NE1-CE2 3.6Å; W388-F392 PolarHBondContact O-N 3.02Å; W388-F445 HydrophobicContact CB-CD2 3.67Å; W388-F445 HydrophobicContact CB-CE2 3.44Å; W388-F445 VanDerWaalsContact CB-CE2 3.44Å; W388-F445 HydrophobicContact CB-CG 4.45Å; W388-F445 HydrophobicContact CB-CZ 4.06Å; W388-F445 AromaticContact CD1-CE2 3.82Å; W388-F445 HydrophobicContact CD2-CD2 4.15Å; W388-F445 AromaticContact CD2-CE2 3.79Å; W388-F445 HydrophobicContact CD2-CE2 3.79Å; W388-F445 HydrophobicContact CE3-CD2 4.26Å; W388-F445 HydrophobicContact CE3-CE2 4.34Å; W388-F445 AromaticContact CG-CD2 3.93Å; W388-F445 HydrophobicContact CG-CD2 3.93Å; W388-F445 AromaticContact CG-CE2 3.38Å; W388-F445 HydrophobicContact CG-CE2 3.38Å; W388-F445 HydrophobicContact CG-CZ 4.16Å; W388-F445 PolarHBondContact N-O 3.17Å; W388-D456 HydrophobicContact CZ3-CB 4.16Å; W388-Y705 AromaticContact CD1-CD1 3.91Å; W388-Y705 AromaticContact CD1-CE1 3.52Å; W388-Y705 HydrophobicContact CG-CE1 4.44Å; W388-Y705 AromaticContact NE1-CD1 3.85Å; W388-Y705 AromaticContact NE1-CE1 3.39Å; W388-Y708 AromaticContact NE1-CE1 3.62Å; W388-Y708 AromaticContact NE1-CZ 3.66Å; W388-Y708 PolarHBondContact NE1-OH 3.15Å
389D98.9Very high98.8Very high2 Ų25.1 Ų5.11%0.0113%0.029CC..Hα-helixtrans-65.1-39.1-179.1-70.8-26000111.6S385 L387 A393 S707S385-D389 WeakPolarHBondContact CB-OD2 3.42Å; S385-D389 WeakPolarHBondContact O-CB 3.31Å; S385-D389 PolarHBondContact O-N 3.42Å; S385-D389 PolarHBondContact OG-OD2 3.2Å; L387-D389 PolarHBondContact O-N 3.23Å; D389-A393 WeakPolarHBondContact O-CB 3.35Å; D389-A393 PolarHBondContact O-N 3.24Å; D389-S707 PolarHBondContact OD2-OG 3.41Å
390T98.9Very high98.8Very high0 Ų05.5 Ų5.50%03%0.033CC..Hα-helixtrans-67.8-39.2179-54.50000112H94 W95 Q386 L387 W388 A393 V394 A415 F418 L419H94-T390 WeakPolarHBondContact CA-OG1 3.07Å; H94-T390 WeakPolarHBondContact CB-OG1 2.97Å; W95-T390 HydrophobicContact CE3-CG2 4.11Å; W95-T390 HydrophobicContact CZ3-CG2 4.08Å; W95-T390 PolarHBondContact N-OG1 2.91Å; Q386-T390 VanDerWaalsContact O-CB 3.25Å; Q386-T390 WeakPolarHBondContact O-CB 3.16Å; Q386-T390 PolarHBondContact O-N 2.82Å; Q386-T390 VanDerWaalsContact O-N 3.11Å; Q386-T390 PolarHBondContact O-OG1 2.83Å; L387-T390 PolarHBondContact O-N 3.47Å; W388-T390 VanDerWaalsContact C-N 3.34Å; W388-T390 PolarHBondContact O-N 3.07Å; T390-A393 PolarHBondContact O-N 2.87Å; T390-V394 WeakPolarHBondContact O-CB 3.27Å; T390-V394 VanDerWaalsContact O-CG2 3.27Å; T390-V394 WeakPolarHBondContact O-CG2 3.44Å; T390-V394 PolarHBondContact O-N 3.31Å; T390-A415 HydrophobicContact CG2-CB 4.11Å; T390-F418 HydrophobicContact CG2-CD1 3.83Å; T390-F418 HydrophobicContact CG2-CE1 4.41Å; T390-L419 HydrophobicContact CG2-CD2 4.41Å
391C98.9Very high98.7Very high0 Ų06.3 Ų6.30%04%0.042CC..Hα-helixtrans-61.8-47.7177.6-68.30000111.2L387 W388 V394 Q395 E460 G461 S464L387-C391 WeakPolarHBondContact O-CB 3.32Å; L387-C391 PolarHBondContact O-N 2.86Å; L387-C391 PolarHBondContact O-SG 3.21Å; W388-C391 PolarHBondContact O-N 2.84Å; C391-V394 PolarHBondContact O-N 2.95Å; C391-Q395 WeakPolarHBondContact O-CG 3.46Å; C391-Q395 PolarHBondContact O-N 3.04Å; C391-Q395 VanDerWaalsContact O-N 3.16Å; C391-E460 HydrophobicContact CB-CB 3.98Å; C391-G461 WeakPolarHBondContact SG-CA 3.48Å; C391-S464 WeakPolarHBondContact CA-OG 3.35Å; C391-S464 PolarHBondContact O-OG 3.23Å
392F98.9Very high98.7Very high3 Ų35.6 Ų5.61%0.0134%0.035CC..Hα-helixtrans-72-36.2178.6-72.3-26.8000113.1W388 V394 Q395 A396 E460 F592 Y708 V711 F712 W715W388-F392 HydrophobicContact CD2-CD2 4.49Å; W388-F392 HydrophobicContact CD2-CE2 4.12Å; W388-F392 AromaticContact CE2-CD2 3.93Å; W388-F392 AromaticContact CE2-CE2 3.32Å; W388-F392 AromaticContact CH2-CE2 3.84Å; W388-F392 HydrophobicContact CH2-CE2 3.84Å; W388-F392 AromaticContact CH2-CZ 3.68Å; W388-F392 HydrophobicContact CH2-CZ 3.68Å; W388-F392 HydrophobicContact CZ2-CD2 4.23Å; W388-F392 AromaticContact CZ2-CE2 3.19Å; W388-F392 HydrophobicContact CZ2-CE2 3.19Å; W388-F392 AromaticContact CZ2-CZ 3.54Å; W388-F392 HydrophobicContact CZ2-CZ 3.54Å; W388-F392 HydrophobicContact CZ3-CZ 4.3Å; W388-F392 AromaticContact NE1-CD2 3.84Å; W388-F392 AromaticContact NE1-CE2 3.6Å; W388-F392 PolarHBondContact O-N 3.02Å; F392-V394 VanDerWaalsContact C-N 3.32Å; F392-V394 PolarHBondContact O-N 3.27Å; F392-Q395 PolarHBondContact O-N 2.93Å; F392-A396 VanDerWaalsContact O-CB 3.3Å; F392-A396 WeakPolarHBondContact O-CB 3.32Å; F392-A396 PolarHBondContact O-N 3Å; F392-E460 HydrophobicContact CE1-CG 3.84Å; F392-E460 HydrophobicContact CZ-CG 4.43Å; F392-F592 HydrophobicContact CZ-CZ 4.47Å; F392-Y708 HydrophobicContact CD2-CE1 4.34Å; F392-V711 HydrophobicContact CB-CG1 3.69Å; F392-F712 HydrophobicContact CD2-CZ 4.35Å; F392-F712 HydrophobicContact CE2-CZ 4.27Å; F392-W715 HydrophobicContact CB-CZ3 3.99Å; F392-W715 AromaticContact CD1-CH2 3.83Å; F392-W715 HydrophobicContact CD1-CH2 3.83Å; F392-W715 AromaticContact CD1-CZ3 3.53Å; F392-W715 HydrophobicContact CD1-CZ3 3.53Å; F392-W715 HydrophobicContact CE1-CH2 4.21Å; F392-W715 HydrophobicContact CE1-CZ3 4.14Å; F392-W715 AromaticContact CG-CZ3 3.92Å; F392-W715 HydrophobicContact CG-CZ3 3.92Å
393A98.9Very high98.6Very high0 Ų06.3 Ų6.30%04%0.037CC..Hα-helixtrans-58.6-45.3173.500000111.2Y85 W95 D389 T390 Q395 A396 F397 V711Y85-A393 HydrophobicContact CE1-CB 4Å; W95-A393 HydrophobicContact CD2-CB 4.19Å; W95-A393 HydrophobicContact CE3-CB 3.98Å; W95-A393 HydrophobicContact CH2-CB 4.38Å; W95-A393 HydrophobicContact CZ3-CB 4.09Å; D389-A393 WeakPolarHBondContact O-CB 3.35Å; D389-A393 PolarHBondContact O-N 3.24Å; T390-A393 PolarHBondContact O-N 2.87Å; A393-Q395 PolarHBondContact O-N 3.07Å; A393-A396 PolarHBondContact O-N 3.41Å; A393-F397 VanDerWaalsContact O-CB 3.31Å; A393-F397 WeakPolarHBondContact O-CB 3.41Å; A393-F397 WeakPolarHBondContact O-CD1 3.44Å; A393-F397 WeakPolarHBondContact O-CG 3.17Å; A393-F397 PolarHBondContact O-N 3.49Å; A393-V711 HydrophobicContact CB-CG2 4.14Å
394V98.9Very high98.5Very high1 Ų112.1 Ų12.11%0.0067%0.068CC..Hα-helixtrans-57.4-49.7174.9163.60000111.3T390 C391 F392 F397 L398 A415 L468T390-V394 WeakPolarHBondContact O-CB 3.27Å; T390-V394 VanDerWaalsContact O-CG2 3.27Å; T390-V394 WeakPolarHBondContact O-CG2 3.44Å; T390-V394 PolarHBondContact O-N 3.31Å; C391-V394 PolarHBondContact O-N 2.95Å; F392-V394 VanDerWaalsContact C-N 3.32Å; F392-V394 PolarHBondContact O-N 3.27Å; V394-F397 PolarHBondContact O-N 3.28Å; V394-L398 HydrophobicContact CG1-CD1 3.86Å; V394-L398 HydrophobicContact CG1-CG 4.39Å; V394-L398 WeakPolarHBondContact O-CB 3.48Å; V394-L398 VanDerWaalsContact O-CG 3.28Å; V394-L398 WeakPolarHBondContact O-CG 3.47Å; V394-L398 PolarHBondContact O-N 2.91Å; V394-A415 HydrophobicContact CG2-CB 3.7Å; V394-L468 HydrophobicContact CB-CD1 4.4Å; V394-L468 HydrophobicContact CG1-CD1 3.56Å; V394-L468 HydrophobicContact CG1-CD2 3.96Å; V394-L468 HydrophobicContact CG1-CG 3.52Å; V394-L468 HydrophobicContact CG2-CD1 3.92Å
395Q98.9Very high98.4Very high7 Ų714.3 Ų14.33%0.0338%0.08CC..Hα-helixtrans-65.5-41.5-178.9-71.2174.254.600112.4C391 F392 A393 L398 E399 E460 K463 S464 L467 W715C391-Q395 WeakPolarHBondContact O-CG 3.46Å; C391-Q395 PolarHBondContact O-N 3.04Å; C391-Q395 VanDerWaalsContact O-N 3.16Å; F392-Q395 PolarHBondContact O-N 2.93Å; A393-Q395 PolarHBondContact O-N 3.07Å; Q395-L398 PolarHBondContact O-N 3.15Å; Q395-E399 WeakPolarHBondContact O-CB 3.43Å; Q395-E399 PolarHBondContact O-N 2.87Å; Q395-E460 PolarHBondContact NE2-OE2 2.85Å; Q395-E460 PolarHBondContact OE1-OE2 2.9Å; Q395-K463 VanDerWaalsContact OE1-NZ 3.15Å; Q395-S464 WeakPolarHBondContact CG-OG 3.46Å; Q395-S464 PolarHBondContact NE2-OG 3.5Å; Q395-L467 HydrophobicContact CG-CD1 4.04Å; Q395-W715 HydrophobicContact CB-CH2 3.69Å; Q395-W715 HydrophobicContact CB-CZ2 3.7Å; Q395-W715 HydrophobicContact CB-CZ3 4.2Å; Q395-W715 HydrophobicContact CG-CH2 4.41Å
396A98.9Very high98.2Very high0 Ų019.2 Ų19.20%011%0.112CC..Hα-helixtrans-60.7-45.8175.200000111.6F392 A393 E399 A400 V711 I714 W715F392-A396 VanDerWaalsContact O-CB 3.3Å; F392-A396 WeakPolarHBondContact O-CB 3.32Å; F392-A396 PolarHBondContact O-N 3Å; A393-A396 PolarHBondContact O-N 3.41Å; A396-E399 PolarHBondContact O-N 2.88Å; A396-A400 WeakPolarHBondContact O-CB 3.1Å; A396-A400 PolarHBondContact O-N 2.86Å; A396-V711 HydrophobicContact CB-CG1 3.93Å; A396-V711 WeakPolarHBondContact CB-O 3.49Å; A396-I714 HydrophobicContact CB-CB 4.42Å; A396-I714 HydrophobicContact CB-CG2 4.16Å; A396-W715 HydrophobicContact CB-CB 3.65Å; A396-W715 HydrophobicContact CB-CD2 4.21Å; A396-W715 HydrophobicContact CB-CE3 4.2Å; A396-W715 HydrophobicContact CB-CG 4.03Å
397F98.9Very high98Very high0 Ų026.2 Ų26.20%014%0.142CC..Hα-helixtrans-64.1-45.5178.6-85.941.8000111M82 Y85 R86 W95 A393 V394 E399 A400 G401 A402 L412 I714M82-F397 HydrophobicContact CB-CE1 4.45Å; M82-F397 HydrophobicContact CB-CE2 4.38Å; M82-F397 HydrophobicContact CB-CZ 4.21Å; M82-F397 HydrophobicContact CG-CD1 4.07Å; M82-F397 HydrophobicContact CG-CD2 4.49Å; M82-F397 HydrophobicContact CG-CE1 4.03Å; M82-F397 HydrophobicContact CG-CE2 4.47Å; M82-F397 HydrophobicContact CG-CG 4.3Å; M82-F397 HydrophobicContact CG-CZ 4.25Å; M82-F397 HydrophobicContact SD-CG 4.31Å; Y85-F397 AromaticContact CD1-CE1 3.87Å; Y85-F397 HydrophobicContact CD1-CE1 3.87Å; Y85-F397 HydrophobicContact CD1-CZ 4.09Å; R86-F397 HydrophobicContact CB-CE2 4.24Å; R86-F397 HydrophobicContact CB-CZ 4.45Å; W95-F397 HydrophobicContact CZ2-CE2 4.46Å; W95-F397 HydrophobicContact CZ2-CZ 4.33Å; A393-F397 VanDerWaalsContact O-CB 3.31Å; A393-F397 WeakPolarHBondContact O-CB 3.41Å; A393-F397 WeakPolarHBondContact O-CD1 3.44Å; A393-F397 WeakPolarHBondContact O-CG 3.17Å; A393-F397 PolarHBondContact O-N 3.49Å; V394-F397 PolarHBondContact O-N 3.28Å; F397-E399 VanDerWaalsContact C-N 3.32Å; F397-E399 PolarHBondContact O-N 3.48Å; F397-A400 CarbonylContact O-C 3.53Å; F397-A400 PolarHBondContact O-N 3.31Å; F397-A400 VanDerWaalsContact O-N 3.16Å; F397-G401 PolarHBondContact O-N 3.03Å; F397-A402 HydrophobicContact CB-CB 3.71Å; F397-A402 HydrophobicContact CD2-CB 4.07Å; F397-A402 HydrophobicContact CG-CB 4.26Å; F397-A402 VanDerWaalsContact O-CB 3.22Å; F397-A402 WeakPolarHBondContact O-CB 3.29Å; F397-A402 PolarHBondContact O-N 3.28Å; F397-L412 HydrophobicContact CB-CD2 4.07Å; F397-L412 HydrophobicContact CD2-CD2 4.25Å; F397-I714 HydrophobicContact CD1-CG2 4.23Å; F397-I714 HydrophobicContact CE1-CD1 3.91Å
398L98.8Very high98Very high6 Ų626.3 Ų26.33%0.03114%0.143CC..Hα-helixtrans-67.5-30.4176.7-68.9179.2000112.3V394 Q395 Q403 L412 L467 L468 F471 R722V394-L398 HydrophobicContact CG1-CD1 3.86Å; V394-L398 HydrophobicContact CG1-CG 4.39Å; V394-L398 WeakPolarHBondContact O-CB 3.48Å; V394-L398 VanDerWaalsContact O-CG 3.28Å; V394-L398 WeakPolarHBondContact O-CG 3.47Å; V394-L398 PolarHBondContact O-N 2.91Å; Q395-L398 PolarHBondContact O-N 3.15Å; L398-Q403 HydrophobicContact CD2-CB 4.06Å; L398-Q403 PolarHBondContact O-OE1 2.68Å; L398-L412 HydrophobicContact CD2-CD1 4.16Å; L398-L467 HydrophobicContact CD1-CB 3.6Å; L398-L468 HydrophobicContact CD1-CD2 4.23Å; L398-L468 HydrophobicContact CD1-CG 4.19Å; L398-F471 HydrophobicContact CD2-CB 4.17Å; L398-R722 VanDerWaalsContact O-CZ 3.22Å; L398-R722 PolarHBondContact O-NH1 3.38Å; L398-R722 PolarHBondContact O-NH2 3.36Å
399E98.2Very high97.8Very high40 Ų4028.1 Ų28.119%0.18715%0.153CC..Hα-helixtrans-73.6-28.1170.4-83-148.2-142.300113.2Q395 A396 F397 G401 W715 G718 R719 R722Q395-E399 WeakPolarHBondContact O-CB 3.43Å; Q395-E399 PolarHBondContact O-N 2.87Å; A396-E399 PolarHBondContact O-N 2.88Å; F397-E399 VanDerWaalsContact C-N 3.32Å; F397-E399 PolarHBondContact O-N 3.48Å; E399-G401 VanDerWaalsContact C-N 3.33Å; E399-W715 VanDerWaalsContact CD-CD1 3.42Å; E399-W715 PolarHBondContact OE1-NE1 3.11Å; E399-G718 CarbonylContact O-C 3.47Å; E399-R719 IonicContact OE1-CZ 3.61Å; E399-R719 IonicContact OE1-NE 3.99Å; E399-R719 PolarHBondContact OE1-NE 2.6Å; E399-R719 IonicContact OE1-NH2 3.54Å; E399-R719 PolarHBondContact OE1-NH2 3.26Å; E399-R719 WeakPolarHBondContact OE2-CB 3.41Å; E399-R719 WeakPolarHBondContact OE2-CG 3.38Å; E399-R719 IonicContact OE2-CZ 2.94Å; E399-R719 IonicContact OE2-NE 3.5Å; E399-R719 PolarHBondContact OE2-NE 2.99Å; E399-R719 IonicContact OE2-NH2 2.72Å; E399-R722 WeakPolarHBondContact O-CD 3.4Å; E399-R722 PolarHBondContact O-NE 2.99Å; E399-R722 PolarHBondContact O-NH2 3.31Å
400A98.4Very high97.8Very high15 Ų1529.8 Ų29.812%0.12417%0.17CC..THydrogen-bonded Turntrans-86.81.4175.700000114.2A78 M82 A396 F397 I714A78-A400 HydrophobicContact CB-CB 4.38Å; M82-A400 HydrophobicContact CE-CB 3.74Å; M82-A400 HydrophobicContact CG-CB 4.41Å; M82-A400 HydrophobicContact SD-CB 3.54Å; M82-A400 VanDerWaalsContact SD-CB 3.54Å; A396-A400 WeakPolarHBondContact O-CB 3.1Å; A396-A400 PolarHBondContact O-N 2.86Å; F397-A400 CarbonylContact O-C 3.53Å; F397-A400 PolarHBondContact O-N 3.31Å; F397-A400 VanDerWaalsContact O-N 3.16Å; A400-I714 HydrophobicContact CB-CG2 3.78Å
401G97.5Very high97.7Very high19 Ų1930.2 Ų30.220%0.19617%0.173CC..THydrogen-bonded Turntrans8522.7174.800000114.7F397 E399 Q403 D404F397-G401 PolarHBondContact O-N 3.03Å; E399-G401 VanDerWaalsContact C-N 3.33Å; G401-Q403 PolarHBondContact O-N 2.92Å; G401-D404 PolarHBondContact O-N 2.77Å
402A97.9Very high97.7Very high0 Ų030.3 Ų30.30%017%0.174CC..G310 helixtrans-58.4-28.6-179.300000113.8M82 F397 D404 D405 L408 L412M82-A402 HydrophobicContact SD-CB 3.82Å; F397-A402 HydrophobicContact CB-CB 3.71Å; F397-A402 HydrophobicContact CD2-CB 4.07Å; F397-A402 HydrophobicContact CG-CB 4.26Å; F397-A402 VanDerWaalsContact O-CB 3.22Å; F397-A402 WeakPolarHBondContact O-CB 3.29Å; F397-A402 PolarHBondContact O-N 3.28Å; A402-D404 PolarHBondContact O-N 2.92Å; A402-D405 PolarHBondContact O-N 3.42Å; A402-L408 HydrophobicContact CB-CB 4.16Å; A402-L408 HydrophobicContact CB-CD1 3.71Å; A402-L412 HydrophobicContact CB-CD1 4.09Å; A402-L412 HydrophobicContact CB-CD2 4.49Å
403Q97.4Very high97.7Very high26 Ų2631.9 Ų31.912%0.12118%0.181CC..G310 helixtrans-63-22177.672.2-76.5-6.100113.3L398 G401 L409 L412 F471L398-Q403 HydrophobicContact CD2-CB 4.06Å; L398-Q403 PolarHBondContact O-OE1 2.68Å; G401-Q403 PolarHBondContact O-N 2.92Å; Q403-L409 WeakPolarHBondContact O-CD2 3.35Å; Q403-L412 HydrophobicContact CB-CD1 4.43Å; Q403-F471 HydrophobicContact CB-CB 4.31Å; Q403-F471 HydrophobicContact CG-CB 4.15Å
404D96Very high97.7Very high125 Ų12535.4 Ų35.467%0.66820%0.2SC*.G310 helixtrans-93.1-6.5-178.7-56.8-51.3000112.2G401 A402 P406G401-D404 PolarHBondContact O-N 2.77Å; A402-D404 PolarHBondContact O-N 2.92Å; D404-P406 WeakPolarHBondContact O-CD 3.27Å
405D96Very high97.7Very high46 Ų4635.4 Ų35.425%0.24620%0.2CC..  trans-101.5110.3175.4-173.4-16.5000110.8A402 K407 L408 L409A402-D405 PolarHBondContact O-N 3.42Å; D405-K407 PolarHBondContact O-N 3.12Å; D405-K407 VanDerWaalsContact OD1-CB 3.28Å; D405-K407 WeakPolarHBondContact OD1-CB 3.37Å; D405-K407 WeakPolarHBondContact OD1-CG 3.39Å; D405-K407 PolarHBondContact OD1-N 3.12Å; D405-L408 HydrophobicContact CB-CB 4.35Å; D405-L408 HydrophobicContact CB-CD1 4.02Å; D405-L408 HydrophobicContact CB-CG 4.08Å; D405-L408 PolarHBondContact O-N 3.23Å; D405-L409 PolarHBondContact O-N 2.98Å
406P94.7Very high97.7Very high105 Ų10535.1 Ų35.168%0.68220%0.198SC*.THydrogen-bonded Turntrans-54.5-25.9178.3-27.135.3000114.5D404 L408D404-P406 WeakPolarHBondContact O-CD 3.27Å; P406-L408 VanDerWaalsContact C-N 3.3Å; P406-L408 PolarHBondContact O-N 2.73Å
407K95.8Very high97.7Very high148 Ų14838 Ų3864%0.64321%0.214SC*.THydrogen-bonded Turntrans-72.2-25.7178.9-60.3176.4180171.80112R86 D405R86-K407 VanDerWaalsContact NH1-C 3.31Å; R86-K407 PolarHBondContact NH1-O 3.37Å; D405-K407 PolarHBondContact O-N 3.12Å; D405-K407 VanDerWaalsContact OD1-CB 3.28Å; D405-K407 WeakPolarHBondContact OD1-CB 3.37Å; D405-K407 WeakPolarHBondContact OD1-CG 3.39Å; D405-K407 PolarHBondContact OD1-N 3.12Å
408L97.4Very high97.7Very high1 Ų138.1 Ų38.11%0.00521%0.214CC..THydrogen-bonded Turntrans-95.2-14.7-175.9-61.3179.7000112.9M82 R86 A402 D405 P406 G410 C411 L412M82-L408 HydrophobicContact CB-CD1 4.06Å; M82-L408 HydrophobicContact CE-CD1 4.19Å; M82-L408 HydrophobicContact SD-CD1 3.92Å; R86-L408 HydrophobicContact CB-CD2 4.36Å; R86-L408 HydrophobicContact CG-CD2 4.3Å; A402-L408 HydrophobicContact CB-CB 4.16Å; A402-L408 HydrophobicContact CB-CD1 3.71Å; D405-L408 HydrophobicContact CB-CB 4.35Å; D405-L408 HydrophobicContact CB-CD1 4.02Å; D405-L408 HydrophobicContact CB-CG 4.08Å; D405-L408 PolarHBondContact O-N 3.23Å; P406-L408 VanDerWaalsContact C-N 3.3Å; P406-L408 PolarHBondContact O-N 2.73Å; L408-G410 VanDerWaalsContact C-N 3.32Å; L408-G410 PolarHBondContact O-N 3.28Å; L408-C411 VanDerWaalsContact O-CB 3.31Å; L408-C411 WeakPolarHBondContact O-CB 3.05Å; L408-C411 PolarHBondContact O-N 3.31Å; L408-C411 VanDerWaalsContact O-N 3.09Å; L408-L412 PolarHBondContact O-N 3.17Å; L408-L412 VanDerWaalsContact O-N 3.16Å
409L96.6Very high97.7Very high47 Ų4737.8 Ų37.825%0.24621%0.213CC..Hα-helixtrans-56.6-40.7-178.3-69.5179.9000114Q403 D405 C411 L412 H413Q403-L409 WeakPolarHBondContact O-CD2 3.35Å; D405-L409 PolarHBondContact O-N 2.98Å; L409-C411 VanDerWaalsContact C-N 3.32Å; L409-C411 PolarHBondContact O-N 3.5Å; L409-L412 PolarHBondContact O-N 3.06Å; L409-H413 PolarHBondContact O-CD2 2.93Å; L409-H413 PolarHBondContact O-N 3.48Å
410G97.6Very high97.7Very high36 Ų3638.9 Ų38.937%0.37122%0.215SC..Hα-helixtrans-60.2-43177.100000112.3L408 L412 H413 D414L408-G410 VanDerWaalsContact C-N 3.32Å; L408-G410 PolarHBondContact O-N 3.28Å; G410-L412 VanDerWaalsContact C-N 3.34Å; G410-L412 PolarHBondContact O-N 2.95Å; G410-H413 PolarHBondContact O-N 2.9Å; G410-D414 VanDerWaalsContact O-CG 3.28Å; G410-D414 PolarHBondContact O-N 3.48Å
411C98.1Very high97.6Very high10 Ų1039.6 Ų39.67%0.06822%0.218CC..Hα-helixtrans-60.8-41.6176.4172.40000111.8R86 Q89 W95 L408 L409 A415R86-C411 HydrophobicContact CB-CB 4.45Å; Q89-C411 PolarHBondContact NE2-O 2.75Å; Q89-C411 VanDerWaalsContact OE1-CA 3.27Å; Q89-C411 PolarHBondContact OE1-SG 2.97Å; W95-C411 WeakPolarHBondContact CH2-SG 3.38Å; W95-C411 VanDerWaalsContact CZ2-SG 3.56Å; L408-C411 VanDerWaalsContact O-CB 3.31Å; L408-C411 WeakPolarHBondContact O-CB 3.05Å; L408-C411 PolarHBondContact O-N 3.31Å; L408-C411 VanDerWaalsContact O-N 3.09Å; L409-C411 VanDerWaalsContact C-N 3.32Å; L409-C411 PolarHBondContact O-N 3.5Å; C411-A415 WeakPolarHBondContact O-CB 3.49Å; C411-A415 PolarHBondContact O-N 2.95Å
412L98.6Very high97.7Very high1 Ų138.7 Ų38.71%0.00521%0.208CC..Hα-helixtrans-68.3-35.9176-62.2178.2000112.8F397 L398 A402 Q403 L408 L409 G410 H416 L468F397-L412 HydrophobicContact CB-CD2 4.07Å; F397-L412 HydrophobicContact CD2-CD2 4.25Å; L398-L412 HydrophobicContact CD2-CD1 4.16Å; A402-L412 HydrophobicContact CB-CD1 4.09Å; A402-L412 HydrophobicContact CB-CD2 4.49Å; Q403-L412 HydrophobicContact CB-CD1 4.43Å; L408-L412 PolarHBondContact O-N 3.17Å; L408-L412 VanDerWaalsContact O-N 3.16Å; L409-L412 PolarHBondContact O-N 3.06Å; G410-L412 VanDerWaalsContact C-N 3.34Å; G410-L412 PolarHBondContact O-N 2.95Å; L412-H416 WeakPolarHBondContact O-CB 3.44Å; L412-H416 PolarHBondContact O-N 3.45Å; L412-L468 HydrophobicContact CB-CD2 3.96Å; L412-L468 HydrophobicContact CD2-CD2 4.2Å
413H98.5Very high97.7Very high37 Ų3738.8 Ų38.817%0.17121%0.209CC..Hα-helixtrans-65.3-46.2174.9-70.3177.2000111.6L409 G410 A415 H416 D417 S474L409-H413 PolarHBondContact O-CD2 2.93Å; L409-H413 PolarHBondContact O-N 3.48Å; G410-H413 PolarHBondContact O-N 2.9Å; H413-A415 VanDerWaalsContact C-N 3.33Å; H413-A415 PolarHBondContact O-N 3.38Å; H413-H416 WeakPolarHBondContact O-CB 3.14Å; H413-H416 PolarHBondContact O-N 3.19Å; H413-D417 PolarHBondContact O-N 2.82Å; H413-S474 PolarHBondContact CE1-O 3.02Å; H413-S474 PolarHBondContact CE1-OG 3.17Å; H413-S474 PolarHBondContact NE2-OG 2.8Å
414D98.5Very high97.8Very high74 Ų7438 Ų3840%0.39621%0.206SC..Hα-helixtrans-64.8-40.5179.2-62.8-24.1000110.7G410 H416 D417 F418G410-D414 VanDerWaalsContact O-CG 3.28Å; G410-D414 PolarHBondContact O-N 3.48Å; D414-H416 PolarHBondContact O-N 3.34Å; D414-D417 PolarHBondContact O-N 3.02Å; D414-F418 PolarHBondContact O-N 3.31Å
415A98.8Very high97.9Very high0 Ų035.7 Ų35.70%020%0.197CC..Hα-helixtrans-62.2-42173.800000112.4G93 W95 T390 V394 C411 H413 D417 F418 L419G93-A415 WeakPolarHBondContact O-CA 3.35Å; W95-A415 HydrophobicContact CH2-CB 4.42Å; W95-A415 HydrophobicContact CZ3-CB 3.98Å; T390-A415 HydrophobicContact CG2-CB 4.11Å; V394-A415 HydrophobicContact CG2-CB 3.7Å; C411-A415 WeakPolarHBondContact O-CB 3.49Å; C411-A415 PolarHBondContact O-N 2.95Å; H413-A415 VanDerWaalsContact C-N 3.33Å; H413-A415 PolarHBondContact O-N 3.38Å; A415-D417 VanDerWaalsContact C-N 3.35Å; A415-F418 PolarHBondContact O-N 2.83Å; A415-L419 WeakPolarHBondContact O-CG 3.25Å; A415-L419 PolarHBondContact O-N 2.83Å
416H98.8Very high98Very high1 Ų139 Ų391%0.00521%0.211CC..Hα-helixtrans-60.3-45173.7178.6-85.7000111.6L412 H413 D414 F418 L419 R420 L468 I475 Q477L412-H416 WeakPolarHBondContact O-CB 3.44Å; L412-H416 PolarHBondContact O-N 3.45Å; H413-H416 WeakPolarHBondContact O-CB 3.14Å; H413-H416 PolarHBondContact O-N 3.19Å; D414-H416 PolarHBondContact O-N 3.34Å; H416-F418 VanDerWaalsContact C-N 3.32Å; H416-F418 PolarHBondContact O-N 3.34Å; H416-L419 PolarHBondContact O-N 3.1Å; H416-R420 WeakPolarHBondContact O-CB 3.07Å; H416-R420 PolarHBondContact O-N 2.69Å; H416-L468 HydrophobicContact CB-CD1 3.95Å; H416-I475 HydrophobicContact CB-CD1 4.14Å; H416-Q477 PolarHBondContact CE1-O 3.16Å; H416-Q477 VanDerWaalsContact CE1-O 3.24Å
417D98.5Very high98.2Very high60 Ų6036.3 Ų36.332%0.32119%0.191SC..Hα-helixtrans-62.6-39.5178.7-86.9-30.4000112.1H413 D414 A415 R420 V421H413-D417 PolarHBondContact O-N 2.82Å; D414-D417 PolarHBondContact O-N 3.02Å; A415-D417 VanDerWaalsContact C-N 3.35Å; D417-R420 PolarHBondContact O-N 3.06Å; D417-R420 IonicContact OD1-CZ 3.74Å; D417-R420 IonicContact OD1-NE 3.76Å; D417-R420 PolarHBondContact OD1-NE 3.36Å; D417-R420 VanDerWaalsContact OD1-NE 3.08Å; D417-R420 IonicContact OD1-NH2 3.07Å; D417-R420 PolarHBondContact OD1-NH2 3.2Å; D417-V421 WeakPolarHBondContact O-CG2 3.48Å; D417-V421 PolarHBondContact O-N 3.13Å
418F98.8Very high98.3Very high3 Ų330.1 Ų30.11%0.01317%0.166CC..Hα-helixtrans-59.8-48.2171.9176.6-106.1000112.5D92 H94 Q386 T390 D414 A415 H416 R420 V421 T422D92-F418 WeakPolarHBondContact O-CB 3.48Å; H94-F418 HydrophobicContact CB-CD1 3.64Å; H94-F418 HydrophobicContact CB-CD2 3.71Å; H94-F418 HydrophobicContact CB-CE1 3.59Å; H94-F418 HydrophobicContact CB-CE2 3.69Å; H94-F418 HydrophobicContact CB-CG 3.69Å; H94-F418 HydrophobicContact CB-CZ 3.62Å; Q386-F418 HydrophobicContact CB-CE1 4.39Å; Q386-F418 HydrophobicContact CB-CZ 3.78Å; T390-F418 HydrophobicContact CG2-CD1 3.83Å; T390-F418 HydrophobicContact CG2-CE1 4.41Å; D414-F418 PolarHBondContact O-N 3.31Å; A415-F418 PolarHBondContact O-N 2.83Å; H416-F418 VanDerWaalsContact C-N 3.32Å; H416-F418 PolarHBondContact O-N 3.34Å; F418-R420 VanDerWaalsContact C-N 3.32Å; F418-R420 PolarHBondContact O-N 3.42Å; F418-V421 PolarHBondContact O-N 2.89Å; F418-T422 WeakPolarHBondContact CE2-OG1 3.32Å; F418-T422 HydrophobicContact CZ-CG2 4.49Å; F418-T422 VanDerWaalsContact CZ-OG1 3.28Å; F418-T422 WeakPolarHBondContact CZ-OG1 3.28Å; F418-T422 WeakPolarHBondContact O-CB 3.45Å; F418-T422 PolarHBondContact O-N 3.45Å; F418-T422 PolarHBondContact O-OG1 3.15Å
419L98.8Very high98.3Very high0 Ų034.7 Ų34.70%020%0.196CC..Hα-helixtrans-61.2-42.4177.7-65.8176.4000111L387 T390 A415 H416 V421 T422 Q423 F443 V465 L468L387-L419 HydrophobicContact CD1-CD2 3.89Å; L387-L419 HydrophobicContact CG-CD2 4.4Å; T390-L419 HydrophobicContact CG2-CD2 4.41Å; A415-L419 WeakPolarHBondContact O-CG 3.25Å; A415-L419 PolarHBondContact O-N 2.83Å; H416-L419 PolarHBondContact O-N 3.1Å; L419-V421 VanDerWaalsContact C-N 3.3Å; L419-V421 PolarHBondContact O-N 3.3Å; L419-T422 PolarHBondContact O-N 2.71Å; L419-T422 VanDerWaalsContact O-N 3.16Å; L419-Q423 PolarHBondContact O-N 3.47Å; L419-F443 WeakPolarHBondContact O-CE1 3.47Å; L419-V465 HydrophobicContact CB-CG2 3.87Å; L419-V465 HydrophobicContact CD1-CG2 4.04Å; L419-L468 HydrophobicContact CD1-CD1 4.11Å
420R98.5Very high98.3Very high62 Ų6238.6 Ų38.623%0.23421%0.213CC..Hα-helixtrans-59-40.1176.4179.3179.861.769.64112.9H416 D417 F418 Q477 I479 R483H416-R420 WeakPolarHBondContact O-CB 3.07Å; H416-R420 PolarHBondContact O-N 2.69Å; D417-R420 PolarHBondContact O-N 3.06Å; D417-R420 IonicContact OD1-CZ 3.74Å; D417-R420 IonicContact OD1-NE 3.76Å; D417-R420 PolarHBondContact OD1-NE 3.36Å; D417-R420 VanDerWaalsContact OD1-NE 3.08Å; D417-R420 IonicContact OD1-NH2 3.07Å; D417-R420 PolarHBondContact OD1-NH2 3.2Å; F418-R420 VanDerWaalsContact C-N 3.32Å; F418-R420 PolarHBondContact O-N 3.42Å; R420-Q477 WeakPolarHBondContact CD-O 3.47Å; R420-I479 HydrophobicContact CB-CD1 4.03Å; R420-I479 HydrophobicContact CB-CG1 4.06Å; R420-I479 HydrophobicContact CG-CD1 4.37Å; R420-I479 HydrophobicContact CG-CG1 4.03Å; R420-R483 PolarHBondContact O-NH2 2.9Å
421V97.2Very high98.3Very high30 Ų3038.7 Ų38.718%0.18220%0.202CC..Hα-helixtrans-71.2-37.8176.6168.10000111.4E31 D417 F418 L419 R448E31-V421 HydrophobicContact CB-CG1 4.01Å; E31-V421 HydrophobicContact CG-CG1 3.93Å; D417-V421 WeakPolarHBondContact O-CG2 3.48Å; D417-V421 PolarHBondContact O-N 3.13Å; F418-V421 PolarHBondContact O-N 2.89Å; L419-V421 VanDerWaalsContact C-N 3.3Å; L419-V421 PolarHBondContact O-N 3.3Å; V421-R448 VanDerWaalsContact O-CD 3.31Å; V421-R448 WeakPolarHBondContact O-CD 3.35Å; V421-R448 PolarHBondContact O-NH1 2.93Å
422T98.7Very high98.4Very high0 Ų044.6 Ų44.60%023%0.229CC..Hα-helixtrans-76.4-28.6-171-58.50000113.9L387 F418 L419 I424 P444L387-T422 HydrophobicContact CB-CG2 4.31Å; L387-T422 HydrophobicContact CD1-CG2 3.41Å; L387-T422 VanDerWaalsContact CD1-CG2 3.41Å; L387-T422 HydrophobicContact CG-CG2 4.47Å; F418-T422 WeakPolarHBondContact CE2-OG1 3.32Å; F418-T422 HydrophobicContact CZ-CG2 4.49Å; F418-T422 VanDerWaalsContact CZ-OG1 3.28Å; F418-T422 WeakPolarHBondContact CZ-OG1 3.28Å; F418-T422 WeakPolarHBondContact O-CB 3.45Å; F418-T422 PolarHBondContact O-N 3.45Å; F418-T422 PolarHBondContact O-OG1 3.15Å; L419-T422 PolarHBondContact O-N 2.71Å; L419-T422 VanDerWaalsContact O-N 3.16Å; T422-I424 PolarHBondContact O-N 2.85Å; T422-P444 HydrophobicContact CG2-CG 4.26Å
423Q98.8Very high98.3Very high3 Ų348.9 Ų48.91%0.01425%0.248CC..SBendtrans-58.1133.6178.3-167.9-172.932.300111.7L419 P425 G441 F443 R483L419-Q423 PolarHBondContact O-N 3.47Å; Q423-P425 WeakPolarHBondContact O-CD 3.16Å; Q423-G441 WeakPolarHBondContact CG-O 3.15Å; Q423-G441 PolarHBondContact NE2-O 3.01Å; Q423-F443 HydrophobicContact CB-CD1 3.97Å; Q423-F443 HydrophobicContact CB-CE1 3.42Å; Q423-F443 VanDerWaalsContact CB-CE1 3.42Å; Q423-F443 HydrophobicContact CB-CE2 4.24Å; Q423-F443 HydrophobicContact CB-CZ 3.56Å; Q423-F443 HydrophobicContact CG-CD1 4.38Å; Q423-F443 HydrophobicContact CG-CD2 4.33Å; Q423-F443 HydrophobicContact CG-CE1 3.94Å; Q423-F443 HydrophobicContact CG-CE2 3.82Å; Q423-F443 HydrophobicContact CG-CZ 3.63Å; Q423-R483 PolarHBondContact NE2-O 3.36Å
424I98.7Very high98.4Very high10 Ų1047.7 Ų47.75%0.05124%0.241CC..  trans-70.8122.7-175.7-57.2-50000110.9T422 E426 N439 G441 G442 P444 R448 I453T422-I424 PolarHBondContact O-N 2.85Å; I424-E426 WeakPolarHBondContact CG2-O 3.2Å; I424-N439 WeakPolarHBondContact CB-O 3.28Å; I424-G441 PolarHBondContact O-N 2.73Å; I424-G442 WeakPolarHBondContact CG1-O 3.48Å; I424-G442 PolarHBondContact N-O 3.22Å; I424-P444 HydrophobicContact CD1-CG 4.34Å; I424-R448 HydrophobicContact CD1-CB 4.47Å; I424-R448 HydrophobicContact CD1-CG 4.04Å; I424-I453 HydrophobicContact CB-CG2 4.49Å; I424-I453 HydrophobicContact CG1-CG2 3.6Å
425P97.9Very high98.4Very high76 Ų7646 Ų4649%0.49423%0.23SC..  trans-78.3-35.4-174.128.9-34.3000113.6Q423 K440Q423-P425 WeakPolarHBondContact O-CD 3.16Å; P425-K440 WeakPolarHBondContact O-CE 3.41Å; P425-K440 WeakPolarHBondContact O-CG 3.35Å
426E98.2Very high98.4Very high115 Ų11546.6 Ų46.654%0.53723%0.232SC..SBendtrans-147156-173.4-65.5-58.3159.200111.9I424 K440I424-E426 WeakPolarHBondContact CG2-O 3.2Å; E426-K440 IonicContact OE1-NZ 3.12Å; E426-K440 PolarHBondContact OE1-NZ 3.18Å; E426-K440 WeakPolarHBondContact OE2-CD 3.34Å; E426-K440 IonicContact OE2-NZ 2.62Å; E426-K440 PolarHBondContact OE2-NZ 2.7Å
427N98.8Very high98.4Very high48 Ų4847.7 Ų47.726%0.25724%0.237SC..PPolyproline II helixtrans-70.9143.5171-63.7-58.5000110.5Y431 M438 N439 K440N427-Y431 HydrophobicContact CB-CD1 3.91Å; N427-Y431 HydrophobicContact CB-CE1 3.98Å; N427-M438 WeakPolarHBondContact OD1-CG 3.31Å; N427-N439 WeakPolarHBondContact CA-OD1 3.47Å; N427-N439 PolarHBondContact OD1-N 3.44Å; N427-N439 PolarHBondContact OD1-OD1 3.48Å; N427-K440 PolarHBondContact OD1-N 3.05Å
428P98.1Very high98.4Very high18 Ų1847.2 Ų47.212%0.11723%0.234CC..PPolyproline II helixtrans-58.9149.8170.3-20.229.1000111.9F330 E430 Y431 N439F330-P428 HydrophobicContact CB-CB 4.4Å; F330-P428 HydrophobicContact CB-CG 4.36Å; F330-P428 HydrophobicContact CD1-CB 3.44Å; F330-P428 VanDerWaalsContact CD1-CB 3.44Å; F330-P428 HydrophobicContact CD1-CG 4.3Å; F330-P428 HydrophobicContact CD2-CB 4.1Å; F330-P428 HydrophobicContact CD2-CG 4.43Å; F330-P428 HydrophobicContact CE1-CB 3.56Å; F330-P428 HydrophobicContact CE2-CB 4.2Å; F330-P428 HydrophobicContact CG-CB 3.72Å; F330-P428 HydrophobicContact CG-CG 4.12Å; F330-P428 HydrophobicContact CZ-CB 3.94Å; P428-E430 PolarHBondContact O-N 3.41Å; P428-Y431 WeakPolarHBondContact O-CB 3.11Å; P428-Y431 WeakPolarHBondContact O-CD1 3.32Å; P428-Y431 PolarHBondContact O-N 2.84Å; P428-N439 WeakPolarHBondContact CD-OD1 3.47Å
429P97.3Very high98.3Very high97 Ų9747.2 Ų47.263%0.6323%0.234SC*.THydrogen-bonded Turntrans-62.9138.2175.426.9-33.5000110.5F330 Y431F330-P429 HydrophobicContact CE1-CG 4.3Å; F330-P429 WeakPolarHBondContact CE1-O 3.32Å; F330-P429 VanDerWaalsContact CZ-O 3.27Å; F330-P429 WeakPolarHBondContact CZ-O 3.42Å; P429-Y431 PolarHBondContact O-N 2.95Å
430E97.3Very high98.3Very high129 Ų12950.2 Ų50.260%0.60325%0.247SC*.THydrogen-bonded Turntrans54.922.9178.8-56-179.594.200114.8P428 Q432 K433 Y434P428-E430 PolarHBondContact O-N 3.41Å; E430-Q432 PolarHBondContact O-N 2.88Å; E430-K433 HydrophobicContact CB-CB 4.49Å; E430-K433 VanDerWaalsContact O-CB 3.31Å; E430-K433 WeakPolarHBondContact O-CB 3.3Å; E430-K433 PolarHBondContact O-N 3.43Å; E430-Y434 HydrophobicContact CB-CE2 4.11Å; E430-Y434 WeakPolarHBondContact O-CD2 3.47Å
431Y98.4Very high98.3Very high39 Ų3947.3 Ų47.315%0.15324%0.237CC..THydrogen-bonded Turntrans-52.7-31.9-171.974.9-83.8000114.3N427 P428 P429 Y434 Y435 R436 M438N427-Y431 HydrophobicContact CB-CD1 3.91Å; N427-Y431 HydrophobicContact CB-CE1 3.98Å; P428-Y431 WeakPolarHBondContact O-CB 3.11Å; P428-Y431 WeakPolarHBondContact O-CD1 3.32Å; P428-Y431 PolarHBondContact O-N 2.84Å; P429-Y431 PolarHBondContact O-N 2.95Å; Y431-Y434 CarbonylContact O-C 3.59Å; Y431-Y434 PolarHBondContact O-N 3.22Å; Y431-Y435 PolarHBondContact O-N 2.85Å; Y431-R436 HydrophobicContact CD2-CB 4.05Å; Y431-R436 VanDerWaalsContact CD2-O 3.24Å; Y431-R436 WeakPolarHBondContact CD2-O 3.47Å; Y431-R436 WeakPolarHBondContact O-CB 3.36Å; Y431-R436 PolarHBondContact O-N 3.1Å; Y431-M438 HydrophobicContact CE2-CB 4.19Å
432Q98.5Very high98.4Very high134 Ų13445.9 Ų45.963%0.62623%0.228SC*.THydrogen-bonded Turntrans-65.8-36177.9-67.2149.8-37.900113E430 Y434 Y435E430-Q432 PolarHBondContact O-N 2.88Å; Q432-Y434 PolarHBondContact O-N 3.2Å; Q432-Y435 PolarHBondContact O-N 3.42Å
433K98.3Very high98.4Very high91 Ų9146 Ų4640%0.39623%0.228SC..THydrogen-bonded Turntrans-57.5-39.6175.4178.4-175.2166.9-159.70110.4D322 E430 Y435D322-K433 IonicContact OD1-NZ 2.78Å; D322-K433 WeakPolarHBondContact OD2-CE 3.27Å; D322-K433 IonicContact OD2-NZ 3.05Å; D322-K433 PolarHBondContact OD2-NZ 2.74Å; E430-K433 HydrophobicContact CB-CB 4.49Å; E430-K433 VanDerWaalsContact O-CB 3.31Å; E430-K433 WeakPolarHBondContact O-CB 3.3Å; E430-K433 PolarHBondContact O-N 3.43Å; K433-Y435 VanDerWaalsContact C-N 3.3Å; K433-Y435 WeakPolarHBondContact O-CD1 3.5Å; K433-Y435 WeakPolarHBondContact O-CE1 3.42Å; K433-Y435 PolarHBondContact O-N 3.19Å
434Y98.8Very high98.4Very high11 Ų1145.9 Ų45.94%0.04323%0.228CC..THydrogen-bonded Turntrans-96.119.3-178.9-48.9-73.6000112.9H323 A326 F330 E430 Y431 Q432 R436H323-Y434 AromaticContact CE1-CD1 3.96Å; H323-Y434 AromaticContact ND1-CD1 3.94Å; A326-Y434 HydrophobicContact CB-CD1 3.34Å; A326-Y434 HydrophobicContact CB-CD2 3.64Å; A326-Y434 HydrophobicContact CB-CE1 3.51Å; A326-Y434 HydrophobicContact CB-CE2 3.8Å; A326-Y434 HydrophobicContact CB-CG 3.38Å; F330-Y434 AromaticContact CE2-CD2 3.74Å; F330-Y434 HydrophobicContact CE2-CD2 3.74Å; F330-Y434 HydrophobicContact CE2-CG 4.19Å; F330-Y434 AromaticContact CZ-CD2 3.59Å; F330-Y434 HydrophobicContact CZ-CD2 3.59Å; F330-Y434 HydrophobicContact CZ-CE2 4.04Å; F330-Y434 HydrophobicContact CZ-CG 4.45Å; E430-Y434 HydrophobicContact CB-CE2 4.11Å; E430-Y434 WeakPolarHBondContact O-CD2 3.47Å; Y431-Y434 CarbonylContact O-C 3.59Å; Y431-Y434 PolarHBondContact O-N 3.22Å; Q432-Y434 PolarHBondContact O-N 3.2Å; Y434-R436 PolarHBondContact O-N 3.47Å
435Y98.7Very high98.4Very high39 Ų3946.2 Ų46.215%0.15323%0.229CC..THydrogen-bonded Turntrans61.124.4172.1-37.8-42.9000114.9W217 H226 S228 R235 H323 Y431 Q432 K433 R508W217-Y435 HydrophobicContact CE3-CE2 4.41Å; W217-Y435 HydrophobicContact CZ3-CE2 4.02Å; H226-Y435 AromaticContact CE1-CZ 3.76Å; H226-Y435 PolarHBondContact CE1-OH 3.22Å; S228-Y435 VanDerWaalsContact CB-CD1 3.42Å; S228-Y435 VanDerWaalsContact CB-CD2 3.48Å; R235-Y435 PolarHBondContact NH2-O 3.16Å; R235-Y435 VanDerWaalsContact NH2-O 3.16Å; H323-Y435 AromaticContact CE1-CD2 3.85Å; H323-Y435 AromaticContact CE1-CE2 3.34Å; H323-Y435 WeakPolarHBondContact CE1-CE2 3.2Å; H323-Y435 AromaticContact CE1-CZ 3.57Å; Y431-Y435 PolarHBondContact O-N 2.85Å; Q432-Y435 PolarHBondContact O-N 3.42Å; K433-Y435 VanDerWaalsContact C-N 3.3Å; K433-Y435 WeakPolarHBondContact O-CD1 3.5Å; K433-Y435 WeakPolarHBondContact O-CE1 3.42Å; K433-Y435 PolarHBondContact O-N 3.19Å; Y435-R508 PolarHBondContact O-NH1 2.88Å; Y435-R508 PolarHBondContact O-NH2 3.16Å
436R98.8Very high98.5Very high12 Ų1242.7 Ų42.75%0.04521%0.206CC..PPolyproline II helixtrans-77.1146.4176.1-69.5-70.6-62.4-96.9-6.2110.6F330 Y431 Y434 N439 G451 W452F330-R436 HydrophobicContact CD2-CG 4.09Å; F330-R436 HydrophobicContact CE2-CG 4.19Å; Y431-R436 HydrophobicContact CD2-CB 4.05Å; Y431-R436 VanDerWaalsContact CD2-O 3.24Å; Y431-R436 WeakPolarHBondContact CD2-O 3.47Å; Y431-R436 WeakPolarHBondContact O-CB 3.36Å; Y431-R436 PolarHBondContact O-N 3.1Å; Y434-R436 PolarHBondContact O-N 3.47Å; R436-N439 PolarHBondContact NH2-ND2 3.05Å; R436-G451 PolarHBondContact NH2-O 3.35Å; R436-W452 VanDerWaalsContact CD-CZ2 3.41Å
437Q98.8Very high98.5Very high25 Ų2537.4 Ų37.412%0.11718%0.182CC..PPolyproline II helixtrans-69.7149.9165.9-171.161.327.700110.6N439 I453 S493 M494 E505Q437-N439 PolarHBondContact O-N 2.87Å; Q437-I453 HydrophobicContact CG-CD1 4.34Å; Q437-S493 PolarHBondContact NE2-O 3.02Å; Q437-S493 PolarHBondContact NE2-OG 2.94Å; Q437-M494 HydrophobicContact CG-CG 4.08Å; Q437-M494 HydrophobicContact CG-SD 4.35Å; Q437-E505 HydrophobicContact CB-CG 4.13Å
438M98.6Very high98.5Very high49 Ų4938.6 Ų38.624%0.24118%0.183CC..PPolyproline II helixtrans-57.4125.7166.7-178.6-170.475.700109.2N427 Y431 N489 V490N427-M438 WeakPolarHBondContact OD1-CG 3.31Å; Y431-M438 HydrophobicContact CE2-CB 4.19Å; M438-N489 HydrophobicContact CE-CB 4.28Å; M438-N489 WeakPolarHBondContact CE-O 3.39Å; M438-V490 HydrophobicContact CE-CG2 4.08Å
439N98.1Very high98.5Very high4 Ų439.1 Ų39.12%0.02119%0.185CC..  trans-126.9-4.7-172.269.9-13.9000115.2I424 N427 P428 R436 Q437 G441 G442 G451 I453I424-N439 WeakPolarHBondContact CB-O 3.28Å; N427-N439 WeakPolarHBondContact CA-OD1 3.47Å; N427-N439 PolarHBondContact OD1-N 3.44Å; N427-N439 PolarHBondContact OD1-OD1 3.48Å; P428-N439 WeakPolarHBondContact CD-OD1 3.47Å; R436-N439 PolarHBondContact NH2-ND2 3.05Å; Q437-N439 PolarHBondContact O-N 2.87Å; N439-G441 PolarHBondContact O-N 3.34Å; N439-G442 PolarHBondContact O-N 3.43Å; N439-G451 PolarHBondContact ND2-O 3.23Å; N439-I453 HydrophobicContact CB-CB 4.19Å; N439-I453 HydrophobicContact CB-CG1 3.39Å; N439-I453 HydrophobicContact CB-CG2 3.72Å
440K98.8Very high98.6Very high62 Ų6234.8 Ų34.827%0.2716%0.156SC..THydrogen-bonded Turntrans-54.4120.6172.5175.2170.3-170.3156.10111.2P425 E426 N427 G442 V490P425-K440 WeakPolarHBondContact O-CE 3.41Å; P425-K440 WeakPolarHBondContact O-CG 3.35Å; E426-K440 IonicContact OE1-NZ 3.12Å; E426-K440 PolarHBondContact OE1-NZ 3.18Å; E426-K440 WeakPolarHBondContact OE2-CD 3.34Å; E426-K440 IonicContact OE2-NZ 2.62Å; E426-K440 PolarHBondContact OE2-NZ 2.7Å; N427-K440 PolarHBondContact OD1-N 3.05Å; K440-G442 VanDerWaalsContact C-N 3.3Å; K440-V490 WeakPolarHBondContact O-CG2 3.39Å
441G98.7Very high98.6Very high2 Ų228.9 Ų28.92%0.02113%0.13CC..THydrogen-bonded Turntrans87-10.5-177.400000114.7Q423 I424 N439 A487Q423-G441 WeakPolarHBondContact CG-O 3.15Å; Q423-G441 PolarHBondContact NE2-O 3.01Å; I424-G441 PolarHBondContact O-N 2.73Å; N439-G441 PolarHBondContact O-N 3.34Å; G441-A487 VanDerWaalsContact O-CA 3.32Å; G441-A487 WeakPolarHBondContact O-CA 3.15Å; G441-A487 VanDerWaalsContact O-CB 3.23Å; G441-A487 WeakPolarHBondContact O-CB 3.5Å
442G98.8Very high98.6Very high0 Ų027.2 Ų27.20%012%0.124CC..  trans-78.1174.1178.100000112.8I424 N439 K440I424-G442 WeakPolarHBondContact CG1-O 3.48Å; I424-G442 PolarHBondContact N-O 3.22Å; N439-G442 PolarHBondContact O-N 3.43Å; K440-G442 VanDerWaalsContact C-N 3.3Å
443F98.9Very high98.7Very high2 Ų221.1 Ų21.11%0.00910%0.095CC..  trans-127134176-64.2-95.9000111.6L387 L419 Q423 I453 V454 T458 V465L387-F443 HydrophobicContact CD1-CB 3.85Å; L387-F443 HydrophobicContact CD1-CD1 3.34Å; L387-F443 HydrophobicContact CD1-CE1 4.16Å; L387-F443 HydrophobicContact CD1-CG 3.99Å; L387-F443 HydrophobicContact CD2-CB 3.61Å; L387-F443 HydrophobicContact CD2-CG 4.41Å; L387-F443 HydrophobicContact CG-CB 4.37Å; L419-F443 WeakPolarHBondContact O-CE1 3.47Å; Q423-F443 HydrophobicContact CB-CD1 3.97Å; Q423-F443 HydrophobicContact CB-CE1 3.42Å; Q423-F443 VanDerWaalsContact CB-CE1 3.42Å; Q423-F443 HydrophobicContact CB-CE2 4.24Å; Q423-F443 HydrophobicContact CB-CZ 3.56Å; Q423-F443 HydrophobicContact CG-CD1 4.38Å; Q423-F443 HydrophobicContact CG-CD2 4.33Å; Q423-F443 HydrophobicContact CG-CE1 3.94Å; Q423-F443 HydrophobicContact CG-CE2 3.82Å; Q423-F443 HydrophobicContact CG-CZ 3.63Å; F443-I453 WeakPolarHBondContact O-CA 3.38Å; F443-V454 PolarHBondContact O-N 3.1Å; F443-V454 VanDerWaalsContact O-N 3.12Å; F443-T458 HydrophobicContact CD2-CG2 4.39Å; F443-T458 PolarHBondContact N-OG1 2.63Å; F443-T458 PolarHBondContact O-OG1 2.86Å; F443-V465 HydrophobicContact CZ-CG2 4.38Å
444P98.8Very high98.7Very high0 Ų017 Ų170%08%0.078CC..BIsolated β-bridgetrans-82.1160174.134.5-33.1000111.6L387 T422 I424 S446 T447 W452L387-P444 WeakPolarHBondContact CB-O 3.27Å; L387-P444 WeakPolarHBondContact CD2-O 3.48Å; T422-P444 HydrophobicContact CG2-CG 4.26Å; I424-P444 HydrophobicContact CD1-CG 4.34Å; P444-S446 VanDerWaalsContact C-N 3.25Å; P444-S446 PolarHBondContact O-N 3.48Å; P444-T447 VanDerWaalsContact CG-C 3.49Å; P444-T447 WeakPolarHBondContact CG-O 3.21Å; P444-W452 VanDerWaalsContact CA-O 3.26Å; P444-W452 WeakPolarHBondContact CA-O 3.31Å; P444-W452 VanDerWaalsContact CB-O 3.24Å; P444-W452 WeakPolarHBondContact CB-O 3.2Å
445F98.9Very high98.7Very high17 Ų1716.5 Ų16.58%0.0758%0.076CC..SBendtrans-58.3-38.1175.1178.1-97.9000113.2Y99 T382 G384 S385 L387 W388 V454 C457 Y705Y99-F445 HydrophobicContact CD1-CE1 4.39Å; Y99-F445 AromaticContact CE1-CE1 3.65Å; Y99-F445 HydrophobicContact CE1-CE1 3.65Å; Y99-F445 HydrophobicContact CE1-CZ 4.15Å; Y99-F445 HydrophobicContact CE2-CE1 4.07Å; Y99-F445 AromaticContact CE2-CZ 3.77Å; Y99-F445 HydrophobicContact CE2-CZ 3.77Å; Y99-F445 AromaticContact CZ-CE1 3.48Å; Y99-F445 VanDerWaalsContact CZ-CE1 3.48Å; Y99-F445 AromaticContact CZ-CZ 3.47Å; Y99-F445 VanDerWaalsContact CZ-CZ 3.47Å; Y99-F445 WeakPolarHBondContact OH-CE1 3.48Å; Y99-F445 VanDerWaalsContact OH-CZ 3.25Å; Y99-F445 WeakPolarHBondContact OH-CZ 3.48Å; T382-F445 HydrophobicContact CG2-CD1 4.16Å; T382-F445 HydrophobicContact CG2-CE1 4.45Å; G384-F445 WeakPolarHBondContact O-CD1 3.44Å; G384-F445 WeakPolarHBondContact O-CE1 3.39Å; S385-F445 VanDerWaalsContact CA-CE1 3.47Å; L387-F445 PolarHBondContact N-O 3.15Å; W388-F445 HydrophobicContact CB-CD2 3.67Å; W388-F445 HydrophobicContact CB-CE2 3.44Å; W388-F445 VanDerWaalsContact CB-CE2 3.44Å; W388-F445 HydrophobicContact CB-CG 4.45Å; W388-F445 HydrophobicContact CB-CZ 4.06Å; W388-F445 AromaticContact CD1-CE2 3.82Å; W388-F445 HydrophobicContact CD2-CD2 4.15Å; W388-F445 AromaticContact CD2-CE2 3.79Å; W388-F445 HydrophobicContact CD2-CE2 3.79Å; W388-F445 HydrophobicContact CE3-CD2 4.26Å; W388-F445 HydrophobicContact CE3-CE2 4.34Å; W388-F445 AromaticContact CG-CD2 3.93Å; W388-F445 HydrophobicContact CG-CD2 3.93Å; W388-F445 AromaticContact CG-CE2 3.38Å; W388-F445 HydrophobicContact CG-CE2 3.38Å; W388-F445 HydrophobicContact CG-CZ 4.16Å; W388-F445 PolarHBondContact N-O 3.17Å; F445-V454 HydrophobicContact CB-CG2 4.22Å; F445-C457 VanDerWaalsContact CA-SG 3.56Å; F445-Y705 AromaticContact CE2-CE1 3.98Å; F445-Y705 HydrophobicContact CE2-CE1 3.98Å; F445-Y705 AromaticContact CZ-CE1 3.75Å; F445-Y705 HydrophobicContact CZ-CE1 3.75Å
446S98.7Very high98.7Very high2 Ų215.2 Ų15.21%0.0147%0.072CC..SBendtrans-102.7-94.5-174.4580000112.1N383 G384 Q386 L387 P444 C450N383-S446 WeakPolarHBondContact OD1-CB 3.41Å; N383-S446 PolarHBondContact OD1-OG 2.96Å; G384-S446 WeakPolarHBondContact O-CB 3.07Å; Q386-S446 VanDerWaalsContact OE1-CA 3.23Å; Q386-S446 VanDerWaalsContact OE1-CB 3.24Å; L387-S446 WeakPolarHBondContact CB-O 3.36Å; L387-S446 PolarHBondContact N-O 2.81Å; L387-S446 VanDerWaalsContact N-O 3.12Å; P444-S446 VanDerWaalsContact C-N 3.25Å; P444-S446 PolarHBondContact O-N 3.48Å; S446-C450 WeakPolarHBondContact OG-CB 3.48Å
447T98.9Very high98.7Very high4 Ų414.7 Ų14.73%0.0257%0.07CC..  trans-130.8159.6-17167.90000112.1N383 Q386 P444 D449 C450 G451N383-T447 PolarHBondContact ND2-OG1 3.08Å; Q386-T447 HydrophobicContact CB-CG2 4.44Å; Q386-T447 VanDerWaalsContact CD-CG2 3.45Å; Q386-T447 HydrophobicContact CG-CG2 4.12Å; Q386-T447 VanDerWaalsContact NE2-CG2 3.27Å; P444-T447 VanDerWaalsContact CG-C 3.49Å; P444-T447 WeakPolarHBondContact CG-O 3.21Å; T447-D449 PolarHBondContact O-N 3.29Å; T447-C450 WeakPolarHBondContact O-CB 3.29Å; T447-C450 PolarHBondContact O-N 3.25Å; T447-C450 VanDerWaalsContact O-N 3.1Å; T447-G451 PolarHBondContact O-N 2.93Å
448R98.6Very high98.7Very high73 Ų7313.5 Ų13.528%0.2756%0.064SC..THydrogen-bonded Turntrans-51.8-41.2176.2177.9174.763.4-167.16.9112.8E31 V421 I424 C450 G451E31-R448 IonicContact OE1-CZ 3.12Å; E31-R448 IonicContact OE1-NH2 3.31Å; E31-R448 PolarHBondContact OE1-NH2 2.93Å; E31-R448 IonicContact OE2-CZ 3.2Å; E31-R448 IonicContact OE2-NH2 2.68Å; E31-R448 PolarHBondContact OE2-NH2 3.12Å; V421-R448 VanDerWaalsContact O-CD 3.31Å; V421-R448 WeakPolarHBondContact O-CD 3.35Å; V421-R448 PolarHBondContact O-NH1 2.93Å; I424-R448 HydrophobicContact CD1-CB 4.47Å; I424-R448 HydrophobicContact CD1-CG 4.04Å; R448-C450 VanDerWaalsContact C-N 3.3Å; R448-C450 PolarHBondContact O-N 3.41Å; R448-G451 WeakPolarHBondContact O-CA 3.37Å; R448-G451 PolarHBondContact O-N 2.66Å; R448-G451 VanDerWaalsContact O-N 3.09Å
449D98.7Very high98.7Very high30 Ų3011.2 Ų11.216%0.165%0.053CC..THydrogen-bonded Turntrans-65.6-30.7-177.2-87.69.8000112.9T331 K332 I334 R365 T447T331-D449 CarbonylContact C-O 3.51Å; T331-D449 VanDerWaalsContact C-O 3.31Å; T331-D449 WeakPolarHBondContact CA-O 3.48Å; T331-D449 VanDerWaalsContact O-O 3.12Å; K332-D449 HydrophobicContact CD-CB 4.32Å; K332-D449 WeakPolarHBondContact CD-OD2 3.48Å; K332-D449 WeakPolarHBondContact CE-OD1 3.21Å; K332-D449 IonicContact NZ-OD1 3.19Å; K332-D449 PolarHBondContact NZ-OD1 2.95Å; K332-D449 IonicContact NZ-OD2 2.77Å; K332-D449 PolarHBondContact NZ-OD2 3.31Å; I334-D449 HydrophobicContact CD1-CB 3.63Å; R365-D449 IonicContact CZ-OD2 3.9Å; R365-D449 IonicContact NH1-OD2 2.84Å; R365-D449 IonicContact NH2-OD2 3.31Å; R365-D449 PolarHBondContact NH2-OD2 3.44Å; T447-D449 PolarHBondContact O-N 3.29Å
450C98.8Very high98.8Very high5 Ų511.1 Ų11.13%0.0345%0.052CC..THydrogen-bonded Turntrans-65.3-44169.91720000111T331 I334 S446 T447 R448 W452T331-C450 WeakPolarHBondContact CG2-O 3.33Å; I334-C450 HydrophobicContact CG2-CB 4.11Å; S446-C450 WeakPolarHBondContact OG-CB 3.48Å; T447-C450 WeakPolarHBondContact O-CB 3.29Å; T447-C450 PolarHBondContact O-N 3.25Å; T447-C450 VanDerWaalsContact O-N 3.1Å; R448-C450 VanDerWaalsContact C-N 3.3Å; R448-C450 PolarHBondContact O-N 3.41Å; C450-W452 PolarHBondContact O-N 2.66Å
451G97.7Very high98.8Very high5 Ų58.1 Ų8.15%0.0524%0.039CC..  trans69.8-2.4168.100000116.4R436 N439 T447 R448 I453R436-G451 PolarHBondContact NH2-O 3.35Å; N439-G451 PolarHBondContact ND2-O 3.23Å; T447-G451 PolarHBondContact O-N 2.93Å; R448-G451 WeakPolarHBondContact O-CA 3.37Å; R448-G451 PolarHBondContact O-N 2.66Å; R448-G451 VanDerWaalsContact O-N 3.09Å; G451-I453 PolarHBondContact O-N 2.82Å
452W98.9Very high98.8Very high5 Ų58.1 Ų8.12%0.0194%0.039CC..  trans-81.995.6172.7-79.595.7000110.1C232 Q236 D327 I336 R436 P444 C450 Y504C232-W452 HydrophobicContact CB-CH2 4.22Å; C232-W452 HydrophobicContact CB-CZ3 3.8Å; Q236-W452 HydrophobicContact CG-CH2 4.19Å; Q236-W452 HydrophobicContact CG-CZ2 4.01Å; D327-W452 PolarHBondContact OD1-NE1 3.32Å; D327-W452 VanDerWaalsContact OD1-NE1 3.13Å; I336-W452 HydrophobicContact CB-CD2 4.04Å; I336-W452 HydrophobicContact CB-CG 3.98Å; I336-W452 HydrophobicContact CB-CZ2 4.48Å; I336-W452 HydrophobicContact CD1-CD2 3.86Å; I336-W452 HydrophobicContact CD1-CE3 3.81Å; I336-W452 HydrophobicContact CD1-CG 4.26Å; I336-W452 HydrophobicContact CD1-CZ3 4.2Å; I336-W452 HydrophobicContact CG1-CB 4.14Å; I336-W452 HydrophobicContact CG1-CD2 3.91Å; I336-W452 HydrophobicContact CG1-CE3 4.36Å; I336-W452 HydrophobicContact CG1-CG 3.82Å; R436-W452 VanDerWaalsContact CD-CZ2 3.41Å; P444-W452 VanDerWaalsContact CA-O 3.26Å; P444-W452 WeakPolarHBondContact CA-O 3.31Å; P444-W452 VanDerWaalsContact CB-O 3.24Å; P444-W452 WeakPolarHBondContact CB-O 3.2Å; C450-W452 PolarHBondContact O-N 2.66Å; W452-Y504 HydrophobicContact CB-CD1 4.01Å; W452-Y504 HydrophobicContact CB-CE1 3.93Å; W452-Y504 HydrophobicContact CE3-CD1 4.2Å
453I98.8Very high98.8Very high5 Ų58.8 Ų8.83%0.0264%0.041CC..BIsolated β-bridgetrans-69.3155.5179.262.975.5000112I424 Q437 N439 F443 G451 V490 M494 Y504I424-I453 HydrophobicContact CB-CG2 4.49Å; I424-I453 HydrophobicContact CG1-CG2 3.6Å; Q437-I453 HydrophobicContact CG-CD1 4.34Å; N439-I453 HydrophobicContact CB-CB 4.19Å; N439-I453 HydrophobicContact CB-CG1 3.39Å; N439-I453 HydrophobicContact CB-CG2 3.72Å; F443-I453 WeakPolarHBondContact O-CA 3.38Å; G451-I453 PolarHBondContact O-N 2.82Å; I453-V490 HydrophobicContact CD1-CG1 3.82Å; I453-V490 HydrophobicContact CG1-CG1 4.34Å; I453-M494 HydrophobicContact CD1-CE 4.37Å; I453-M494 HydrophobicContact CD1-SD 3.96Å; I453-Y504 WeakPolarHBondContact O-CA 3.49Å; I453-Y504 WeakPolarHBondContact O-CD1 2.97Å
454V98.9Very high98.8Very high5 Ų58.7 Ų8.73%0.034%0.041CC..  trans-132.7146.8177.3-1560000108.7F443 F445 D456 C457 T458 T503 Y504F443-V454 PolarHBondContact O-N 3.1Å; F443-V454 VanDerWaalsContact O-N 3.12Å; F445-V454 HydrophobicContact CB-CG2 4.22Å; V454-D456 WeakPolarHBondContact CG1-OD1 3.4Å; V454-C457 HydrophobicContact CB-CB 3.82Å; V454-C457 HydrophobicContact CG2-CB 4.18Å; V454-C457 PolarHBondContact O-N 3.07Å; V454-T458 WeakPolarHBondContact O-CB 3.35Å; V454-T458 PolarHBondContact O-N 2.89Å; V454-T458 PolarHBondContact O-OG1 3.44Å; V454-T503 CarbonylContact C-O 3.49Å; V454-T503 WeakPolarHBondContact CA-O 3.37Å; V454-T503 VanDerWaalsContact CG1-C 3.49Å; V454-T503 VanDerWaalsContact CG1-O 3.31Å; V454-T503 WeakPolarHBondContact CG1-O 3.48Å; V454-Y504 HydrophobicContact CG2-CD1 3.83Å; V454-Y504 HydrophobicContact CG2-CE1 3.55Å; V454-Y504 HydrophobicContact CG2-CG 4.43Å
455A98.9Very high98.8Very high0 Ų08.7 Ų8.70%04%0.041CC..Hα-helixtrans-60.2-50.7-177.900000112.1T458 A459 L491 M494 F501 A502 T503A455-T458 PolarHBondContact O-N 2.8Å; A455-A459 WeakPolarHBondContact O-CB 3.32Å; A455-A459 PolarHBondContact O-N 3.27Å; A455-L491 HydrophobicContact CB-CD2 4.45Å; A455-L491 VanDerWaalsContact O-CD2 3.24Å; A455-L491 WeakPolarHBondContact O-CD2 3.24Å; A455-M494 HydrophobicContact CB-CE 3.74Å; A455-M494 HydrophobicContact CB-SD 4.25Å; A455-F501 HydrophobicContact CB-CB 4.43Å; A455-F501 HydrophobicContact CB-CD1 4.18Å; A455-A502 WeakPolarHBondContact CB-O 3.46Å; A455-T503 PolarHBondContact N-O 2.92Å
456D98.8Very high98.8Very high13 Ų138.2 Ų8.27%0.074%0.039CC..Hα-helixtrans-65.8-44.5176.744.524.9000112.1W388 V454 T458 A459 E460 C534 A537W388-D456 HydrophobicContact CZ3-CB 4.16Å; V454-D456 WeakPolarHBondContact CG1-OD1 3.4Å; D456-T458 VanDerWaalsContact C-N 3.26Å; D456-T458 PolarHBondContact O-N 2.92Å; D456-A459 CarbonylContact O-C 3.56Å; D456-A459 WeakPolarHBondContact O-CB 3.33Å; D456-A459 PolarHBondContact O-N 3.1Å; D456-A459 VanDerWaalsContact O-N 3.08Å; D456-E460 WeakPolarHBondContact O-CB 3.23Å; D456-E460 VanDerWaalsContact O-CG 3.32Å; D456-E460 WeakPolarHBondContact O-CG 3.3Å; D456-E460 PolarHBondContact O-N 3.04Å; D456-C534 PolarHBondContact OD2-SG 2.84Å; D456-A537 HydrophobicContact CB-CB 3.97Å
457C98.9Very high98.8Very high1 Ų19.7 Ų9.71%0.0075%0.047CC..Hα-helixtrans-60.8-38.9177.4-60.40000111.3L387 F445 V454 G461L387-C457 HydrophobicContact CD2-CB 3.83Å; L387-C457 WeakPolarHBondContact CD2-O 3.42Å; F445-C457 VanDerWaalsContact CA-SG 3.56Å; V454-C457 HydrophobicContact CB-CB 3.82Å; V454-C457 HydrophobicContact CG2-CB 4.18Å; V454-C457 PolarHBondContact O-N 3.07Å; C457-G461 PolarHBondContact O-N 3.12Å
458T98.9Very high98.8Very high0 Ų09.5 Ų9.50%05%0.046CC..Hα-helixtrans-67.1-41.1174.2-60.10000111.6F443 V454 A455 D456 L462 A487 V490 L491F443-T458 HydrophobicContact CD2-CG2 4.39Å; F443-T458 PolarHBondContact N-OG1 2.63Å; F443-T458 PolarHBondContact O-OG1 2.86Å; V454-T458 WeakPolarHBondContact O-CB 3.35Å; V454-T458 PolarHBondContact O-N 2.89Å; V454-T458 PolarHBondContact O-OG1 3.44Å; A455-T458 PolarHBondContact O-N 2.8Å; D456-T458 VanDerWaalsContact C-N 3.26Å; D456-T458 PolarHBondContact O-N 2.92Å; T458-L462 VanDerWaalsContact O-CB 3.22Å; T458-L462 WeakPolarHBondContact O-CB 3.13Å; T458-L462 PolarHBondContact O-N 3.17Å; T458-A487 HydrophobicContact CG2-CB 4.23Å; T458-V490 HydrophobicContact CG2-CB 4.44Å; T458-V490 HydrophobicContact CG2-CG1 4.32Å; T458-L491 HydrophobicContact CG2-CD2 4.03Å; T458-L491 HydrophobicContact CG2-CG 4.05Å
459A98.9Very high98.7Very high0 Ų08.3 Ų8.30%04%0.043CC..Hα-helixtrans-65.6-49.2177.600000111.9A455 D456 L462 K463 L491 A537 A541A455-A459 WeakPolarHBondContact O-CB 3.32Å; A455-A459 PolarHBondContact O-N 3.27Å; D456-A459 CarbonylContact O-C 3.56Å; D456-A459 WeakPolarHBondContact O-CB 3.33Å; D456-A459 PolarHBondContact O-N 3.1Å; D456-A459 VanDerWaalsContact O-N 3.08Å; A459-L462 PolarHBondContact O-N 3.36Å; A459-K463 VanDerWaalsContact O-CB 3.26Å; A459-K463 WeakPolarHBondContact O-CB 3.42Å; A459-K463 PolarHBondContact O-N 3.05Å; A459-L491 HydrophobicContact CB-CD1 4.25Å; A459-L491 HydrophobicContact CB-CD2 4.36Å; A459-A537 HydrophobicContact CB-CB 4.14Å; A459-A537 WeakPolarHBondContact CB-O 3.38Å; A459-A541 HydrophobicContact CB-CB 3.72Å; A459-A541 VanDerWaalsContact O-CB 3.25Å; A459-A541 WeakPolarHBondContact O-CB 3.42Å
460E98.9Very high98.7Very high2 Ų212.1 Ų12.11%0.0096%0.06CC..Hα-helixtrans-66.6-39.5178.6-62.6-54.6148.500111.5C391 F392 Q395 D456 K463 S464 A537C391-E460 HydrophobicContact CB-CB 3.98Å; F392-E460 HydrophobicContact CE1-CG 3.84Å; F392-E460 HydrophobicContact CZ-CG 4.43Å; Q395-E460 PolarHBondContact NE2-OE2 2.85Å; Q395-E460 PolarHBondContact OE1-OE2 2.9Å; D456-E460 WeakPolarHBondContact O-CB 3.23Å; D456-E460 VanDerWaalsContact O-CG 3.32Å; D456-E460 WeakPolarHBondContact O-CG 3.3Å; D456-E460 PolarHBondContact O-N 3.04Å; E460-K463 VanDerWaalsContact CD-NZ 3.28Å; E460-K463 PolarHBondContact O-N 3.37Å; E460-K463 IonicContact OE1-NZ 2.58Å; E460-K463 PolarHBondContact OE1-NZ 3.22Å; E460-K463 WeakPolarHBondContact OE2-CE 3.35Å; E460-K463 IonicContact OE2-NZ 3.59Å; E460-K463 PolarHBondContact OE2-NZ 3.02Å; E460-S464 VanDerWaalsContact O-CB 3.31Å; E460-S464 WeakPolarHBondContact O-CB 3.47Å; E460-S464 PolarHBondContact O-N 3.34Å; E460-S464 PolarHBondContact O-OG 2.94Å; E460-S464 VanDerWaalsContact O-OG 3.05Å; E460-A537 HydrophobicContact CG-CB 4.48Å; E460-A537 WeakPolarHBondContact OE1-CB 3.47Å
461G98.9Very high98.6Very high0 Ų015.9 Ų15.90%08%0.076CC..Hα-helixtrans-60.9-47172.200000112.9C391 C457 V465C391-G461 WeakPolarHBondContact SG-CA 3.48Å; C457-G461 PolarHBondContact O-N 3.12Å; G461-V465 WeakPolarHBondContact O-CB 3.38Å; G461-V465 VanDerWaalsContact O-CG2 3.29Å; G461-V465 WeakPolarHBondContact O-CG2 3.49Å; G461-V465 PolarHBondContact O-N 3.32Å
462L98.9Very high98.6Very high2 Ų215.8 Ų15.81%0.017%0.074CC..Hα-helixtrans-60.7-47.6175.4175.660.3000111.3T458 A459 V465 M466 L484 A487 V488 L491T458-L462 VanDerWaalsContact O-CB 3.22Å; T458-L462 WeakPolarHBondContact O-CB 3.13Å; T458-L462 PolarHBondContact O-N 3.17Å; A459-L462 PolarHBondContact O-N 3.36Å; L462-V465 PolarHBondContact O-N 2.96Å; L462-M466 HydrophobicContact CD1-CG 4.16Å; L462-M466 HydrophobicContact CD1-SD 4.01Å; L462-M466 HydrophobicContact CG-SD 4.14Å; L462-M466 WeakPolarHBondContact O-CB 3.45Å; L462-M466 VanDerWaalsContact O-CG 3.31Å; L462-M466 WeakPolarHBondContact O-CG 3.2Å; L462-M466 PolarHBondContact O-N 3.18Å; L462-L484 HydrophobicContact CD1-CB 4.15Å; L462-L484 HydrophobicContact CD1-CD2 3.9Å; L462-A487 HydrophobicContact CB-CB 4.43Å; L462-A487 HydrophobicContact CD1-CB 4.22Å; L462-A487 HydrophobicContact CD2-CB 4.36Å; L462-V488 HydrophobicContact CD2-CG2 3.71Å; L462-L491 HydrophobicContact CD2-CD1 4.45Å
463K98.8Very high98.3Very high13 Ų1321.2 Ų21.26%0.05711%0.111CC..Hα-helixtrans-61.7-47.8-179.4-163.1170.974.5-167.10110.9Q395 A459 E460 M466 L467 Q540 A541Q395-K463 VanDerWaalsContact OE1-NZ 3.15Å; A459-K463 VanDerWaalsContact O-CB 3.26Å; A459-K463 WeakPolarHBondContact O-CB 3.42Å; A459-K463 PolarHBondContact O-N 3.05Å; E460-K463 VanDerWaalsContact CD-NZ 3.28Å; E460-K463 PolarHBondContact O-N 3.37Å; E460-K463 IonicContact OE1-NZ 2.58Å; E460-K463 PolarHBondContact OE1-NZ 3.22Å; E460-K463 WeakPolarHBondContact OE2-CE 3.35Å; E460-K463 IonicContact OE2-NZ 3.59Å; E460-K463 PolarHBondContact OE2-NZ 3.02Å; K463-M466 PolarHBondContact O-N 3.48Å; K463-L467 HydrophobicContact CG-CD1 4.07Å; K463-L467 WeakPolarHBondContact O-CB 3.4Å; K463-L467 WeakPolarHBondContact O-CG 3.48Å; K463-L467 PolarHBondContact O-N 2.97Å; K463-Q540 HydrophobicContact CD-CB 4.16Å; K463-A541 HydrophobicContact CB-CB 4.25Å
464S98.9Very high98Very high0 Ų023.5 Ų23.50%013%0.127CC..Hα-helixtrans-63.2-42.3178.4-65.90000112.8C391 Q395 E460 L468C391-S464 WeakPolarHBondContact CA-OG 3.35Å; C391-S464 PolarHBondContact O-OG 3.23Å; Q395-S464 WeakPolarHBondContact CG-OG 3.46Å; Q395-S464 PolarHBondContact NE2-OG 3.5Å; E460-S464 VanDerWaalsContact O-CB 3.31Å; E460-S464 WeakPolarHBondContact O-CB 3.47Å; E460-S464 PolarHBondContact O-N 3.34Å; E460-S464 PolarHBondContact O-OG 2.94Å; E460-S464 VanDerWaalsContact O-OG 3.05Å; S464-L468 WeakPolarHBondContact O-CB 3.31Å; S464-L468 WeakPolarHBondContact O-CD1 3.4Å; S464-L468 VanDerWaalsContact O-CG 3.31Å; S464-L468 WeakPolarHBondContact O-CG 3.4Å; S464-L468 PolarHBondContact O-N 3.47Å
465V98.8Very high97.8Very high1 Ų124.2 Ų24.21%0.00613%0.13CC..Hα-helixtrans-60.5-48.2174.5166.50000111L419 F443 G461 L462 L468 Q469 I479 L484L419-V465 HydrophobicContact CB-CG2 3.87Å; L419-V465 HydrophobicContact CD1-CG2 4.04Å; F443-V465 HydrophobicContact CZ-CG2 4.38Å; G461-V465 WeakPolarHBondContact O-CB 3.38Å; G461-V465 VanDerWaalsContact O-CG2 3.29Å; G461-V465 WeakPolarHBondContact O-CG2 3.49Å; G461-V465 PolarHBondContact O-N 3.32Å; L462-V465 PolarHBondContact O-N 2.96Å; V465-L468 PolarHBondContact O-N 3.42Å; V465-Q469 VanDerWaalsContact O-CG 3.3Å; V465-Q469 WeakPolarHBondContact O-CG 3.41Å; V465-Q469 PolarHBondContact O-N 2.9Å; V465-I479 HydrophobicContact CB-CD1 4.48Å; V465-I479 HydrophobicContact CG1-CB 4.04Å; V465-I479 HydrophobicContact CG1-CD1 3.79Å; V465-I479 HydrophobicContact CG1-CG1 4.05Å; V465-I479 HydrophobicContact CG2-CD1 3.8Å; V465-L484 HydrophobicContact CG1-CD2 3.83Å
466M98.6Very high97.1Very high7 Ų735.1 Ų35.13%0.03417%0.172CC..Hα-helixtrans-61.1-48.3-179.5-75.3-177.670.200112.1L462 K463 L468 Q469 E470 L484 H544 F545 V548L462-M466 HydrophobicContact CD1-CG 4.16Å; L462-M466 HydrophobicContact CD1-SD 4.01Å; L462-M466 HydrophobicContact CG-SD 4.14Å; L462-M466 WeakPolarHBondContact O-CB 3.45Å; L462-M466 VanDerWaalsContact O-CG 3.31Å; L462-M466 WeakPolarHBondContact O-CG 3.2Å; L462-M466 PolarHBondContact O-N 3.18Å; K463-M466 PolarHBondContact O-N 3.48Å; M466-L468 PolarHBondContact O-N 3.48Å; M466-Q469 PolarHBondContact O-N 2.94Å; M466-E470 WeakPolarHBondContact O-CB 3.21Å; M466-E470 PolarHBondContact O-N 3.49Å; M466-L484 HydrophobicContact CG-CD1 4.49Å; M466-H544 VanDerWaalsContact CE-CD2 3.47Å; M466-H544 WeakPolarHBondContact CE-CD2 3.46Å; M466-F545 VanDerWaalsContact CE-CA 3.49Å; M466-F545 HydrophobicContact CE-CB 4.26Å; M466-F545 HydrophobicContact CE-CD2 4.42Å; M466-F545 HydrophobicContact SD-CB 4Å; M466-F545 HydrophobicContact SD-CD2 4.07Å; M466-V548 HydrophobicContact CE-CB 3.62Å; M466-V548 HydrophobicContact CE-CG1 4.16Å; M466-V548 HydrophobicContact CE-CG2 3.51Å
467L98.6Very high96.9Very high32 Ų3240 Ų4017%0.16819%0.194CC..Hα-helixtrans-61.6-42.7178.9-67.9169000111.5Q395 L398 K463 Q469 E470 F471Q395-L467 HydrophobicContact CG-CD1 4.04Å; L398-L467 HydrophobicContact CD1-CB 3.6Å; K463-L467 HydrophobicContact CG-CD1 4.07Å; K463-L467 WeakPolarHBondContact O-CB 3.4Å; K463-L467 WeakPolarHBondContact O-CG 3.48Å; K463-L467 PolarHBondContact O-N 2.97Å; L467-Q469 PolarHBondContact O-N 3.46Å; L467-E470 PolarHBondContact O-N 3.09Å; L467-F471 HydrophobicContact CB-CD2 4.31Å; L467-F471 HydrophobicContact CD2-CD2 4.26Å; L467-F471 HydrophobicContact CD2-CE2 3.73Å; L467-F471 WeakPolarHBondContact O-CB 3.35Å; L467-F471 VanDerWaalsContact O-CD2 3.22Å; L467-F471 WeakPolarHBondContact O-CD2 3.36Å; L467-F471 PolarHBondContact O-N 3.44Å
468L98.7Very high96.7Very high0 Ų043.7 Ų43.70%022%0.218CC..Hα-helixtrans-59.7-46.6175.1-81165.9000111.8V394 L398 L412 H416 L419 S464 V465 M466 E470 C472 I475V394-L468 HydrophobicContact CB-CD1 4.4Å; V394-L468 HydrophobicContact CG1-CD1 3.56Å; V394-L468 HydrophobicContact CG1-CD2 3.96Å; V394-L468 HydrophobicContact CG1-CG 3.52Å; V394-L468 HydrophobicContact CG2-CD1 3.92Å; L398-L468 HydrophobicContact CD1-CD2 4.23Å; L398-L468 HydrophobicContact CD1-CG 4.19Å; L412-L468 HydrophobicContact CB-CD2 3.96Å; L412-L468 HydrophobicContact CD2-CD2 4.2Å; H416-L468 HydrophobicContact CB-CD1 3.95Å; L419-L468 HydrophobicContact CD1-CD1 4.11Å; S464-L468 WeakPolarHBondContact O-CB 3.31Å; S464-L468 WeakPolarHBondContact O-CD1 3.4Å; S464-L468 VanDerWaalsContact O-CG 3.31Å; S464-L468 WeakPolarHBondContact O-CG 3.4Å; S464-L468 PolarHBondContact O-N 3.47Å; V465-L468 PolarHBondContact O-N 3.42Å; M466-L468 PolarHBondContact O-N 3.48Å; L468-E470 VanDerWaalsContact C-N 3.3Å; L468-E470 PolarHBondContact O-N 3.25Å; L468-C472 WeakPolarHBondContact O-CA 3.3Å; L468-C472 WeakPolarHBondContact O-CB 3.39Å; L468-C472 PolarHBondContact O-N 2.95Å; L468-I475 HydrophobicContact CB-CD1 3.75Å; L468-I475 VanDerWaalsContact O-CD1 3.31Å; L468-I475 WeakPolarHBondContact O-CD1 3.42Å
469Q97.9Very high96.7Very high49 Ų4943.9 Ų43.923%0.22922%0.219CC..Hα-helixtrans-67.9-29.2179.9-67.3179.4159.400113.1V465 M466 L467 P478 I479V465-Q469 VanDerWaalsContact O-CG 3.3Å; V465-Q469 WeakPolarHBondContact O-CG 3.41Å; V465-Q469 PolarHBondContact O-N 2.9Å; M466-Q469 PolarHBondContact O-N 2.94Å; L467-Q469 PolarHBondContact O-N 3.46Å; Q469-P478 HydrophobicContact CG-CB 4.17Å; Q469-P478 VanDerWaalsContact OE1-CA 3.29Å; Q469-P478 VanDerWaalsContact OE1-CB 3.26Å; Q469-I479 PolarHBondContact OE1-O 3.13Å
470E97.2Very high96.6Very high110 Ų11046.1 Ų46.151%0.51424%0.241SC..Hα-helixtrans-75.6-48.1175.8-175.7178.2168.900111.9M466 L467 L468 H544M466-E470 WeakPolarHBondContact O-CB 3.21Å; M466-E470 PolarHBondContact O-N 3.49Å; L467-E470 PolarHBondContact O-N 3.09Å; L468-E470 VanDerWaalsContact C-N 3.3Å; L468-E470 PolarHBondContact O-N 3.25Å; E470-H544 IonicContact OE2-CE1 3.5Å; E470-H544 PolarHBondContact OE2-CE1 3.03Å; E470-H544 VanDerWaalsContact OE2-CE1 3.31Å; E470-H544 IonicContact OE2-NE2 3.4Å
471F97.4Very high96.5Very high84 Ų8448.6 Ų48.637%0.36826%0.259SS..Hα-helixtrans-90.9-16.5-172.3-69.8-65.6000114.2L398 Q403 L467 P473L398-F471 HydrophobicContact CD2-CB 4.17Å; Q403-F471 HydrophobicContact CB-CB 4.31Å; Q403-F471 HydrophobicContact CG-CB 4.15Å; L467-F471 HydrophobicContact CB-CD2 4.31Å; L467-F471 HydrophobicContact CD2-CD2 4.26Å; L467-F471 HydrophobicContact CD2-CE2 3.73Å; L467-F471 WeakPolarHBondContact O-CB 3.35Å; L467-F471 VanDerWaalsContact O-CD2 3.22Å; L467-F471 WeakPolarHBondContact O-CD2 3.36Å; L467-F471 PolarHBondContact O-N 3.44Å; F471-P473 WeakPolarHBondContact O-CD 3.11Å
472C97Very high96.4Very high2 Ų254.2 Ų54.21%0.01429%0.285CS..  trans-123.177.7-178.6-56.70000111.1L468 S474 I475L468-C472 WeakPolarHBondContact O-CA 3.3Å; L468-C472 WeakPolarHBondContact O-CB 3.39Å; L468-C472 PolarHBondContact O-N 2.95Å; C472-S474 PolarHBondContact O-N 3.31Å; C472-I475 HydrophobicContact CB-CD1 3.84Å; C472-I475 HydrophobicContact CB-CG1 4.01Å; C472-I475 WeakPolarHBondContact O-CG1 3.32Å; C472-I475 PolarHBondContact O-N 2.96Å; C472-I475 VanDerWaalsContact O-N 3.08Å
473P92.6Very high96.4Very high120 Ų12057.8 Ų57.878%0.77930%0.299SS*.THydrogen-bonded Turntrans-64.1-10.4-178.627-36000113.9F471 I475F471-P473 WeakPolarHBondContact O-CD 3.11Å; P473-I475 VanDerWaalsContact C-N 3.29Å
474S93.8Very high96.4Very high53 Ų5357.5 Ų57.537%0.37130%0.298SS..THydrogen-bonded Turntrans-79.6-4175.754.90000114.2H413 C472 R476H413-S474 PolarHBondContact CE1-O 3.02Å; H413-S474 PolarHBondContact CE1-OG 3.17Å; H413-S474 PolarHBondContact NE2-OG 2.8Å; C472-S474 PolarHBondContact O-N 3.31Å; S474-R476 PolarHBondContact O-N 3.39Å
475I95.2Very high96.4Very high20 Ų2059.9 Ų59.910%0.10331%0.307CS..  trans-61.6123.3174.6-72.9170.4000110H416 L468 C472 P473H416-I475 HydrophobicContact CB-CD1 4.14Å; L468-I475 HydrophobicContact CB-CD1 3.75Å; L468-I475 VanDerWaalsContact O-CD1 3.31Å; L468-I475 WeakPolarHBondContact O-CD1 3.42Å; C472-I475 HydrophobicContact CB-CD1 3.84Å; C472-I475 HydrophobicContact CB-CG1 4.01Å; C472-I475 WeakPolarHBondContact O-CG1 3.32Å; C472-I475 PolarHBondContact O-N 2.96Å; C472-I475 VanDerWaalsContact O-N 3.08Å; P473-I475 VanDerWaalsContact C-N 3.29Å
476R84.1Confident96.4Very high229 Ų22961.1 Ų61.186%0.86431%0.314SS*.SBendtrans-79.1-35.3-170.5-60.8178.7-176.8173.12113.9S474S474-R476 PolarHBondContact O-N 3.39Å
477Q93.1Very high96.4Very high114 Ų11460.8 Ų60.853%0.53331%0.312SS..SBendtrans-128.869.7-173.4-64.8-171.111.400110.9H416 R420H416-Q477 PolarHBondContact CE1-O 3.16Å; H416-Q477 VanDerWaalsContact CE1-O 3.24Å; R420-Q477 WeakPolarHBondContact CD-O 3.47Å
478P96.1Very high96.4Very high79 Ų7959.2 Ų59.251%0.51330%0.304SS..  trans-60.2146.5178.226.8-34.6000111.5Q469 G480Q469-P478 HydrophobicContact CG-CB 4.17Å; Q469-P478 VanDerWaalsContact OE1-CA 3.29Å; Q469-P478 VanDerWaalsContact OE1-CB 3.26Å; P478-G480 PolarHBondContact O-N 3.35Å
479I97.4Very high96.4Very high5 Ų561.2 Ų61.23%0.02632%0.315CS..  trans-66.8115167.2-57.1-167.9000108.7R420 V465 Q469 R483 L484R420-I479 HydrophobicContact CB-CD1 4.03Å; R420-I479 HydrophobicContact CB-CG1 4.06Å; R420-I479 HydrophobicContact CG-CD1 4.37Å; R420-I479 HydrophobicContact CG-CG1 4.03Å; V465-I479 HydrophobicContact CB-CD1 4.48Å; V465-I479 HydrophobicContact CG1-CB 4.04Å; V465-I479 HydrophobicContact CG1-CD1 3.79Å; V465-I479 HydrophobicContact CG1-CG1 4.05Å; V465-I479 HydrophobicContact CG2-CD1 3.8Å; Q469-I479 PolarHBondContact OE1-O 3.13Å; I479-R483 HydrophobicContact CG2-CB 3.43Å; I479-R483 VanDerWaalsContact CG2-CB 3.43Å; I479-R483 HydrophobicContact CG2-CG 4.38Å; I479-L484 HydrophobicContact CB-CD2 4.34Å; I479-L484 HydrophobicContact CG2-CD2 3.96Å; I479-L484 HydrophobicContact CG2-CG 4.45Å
480G96.9Very high96.5Very high46 Ų4658.9 Ų58.947%0.47430%0.304SS..  trans-63.8153.2178.600000113.3P478 Q482 R483 L484P478-G480 PolarHBondContact O-N 3.35Å; G480-Q482 PolarHBondContact O-N 2.9Å; G480-R483 PolarHBondContact O-N 3.23Å; G480-L484 PolarHBondContact O-N 3.36Å
481S97Very high96.6Very high54 Ų5453.7 Ų53.738%0.37828%0.279SS..Hα-helixtrans-53-35.1-171.5-44.10000114.4R483 L484 Y485S481-R483 VanDerWaalsContact C-N 3.28Å; S481-R483 PolarHBondContact O-N 3.42Å; S481-L484 WeakPolarHBondContact O-CA 3.28Å; S481-L484 WeakPolarHBondContact O-CB 3.45Å; S481-L484 PolarHBondContact O-N 3.25Å; S481-Y485 WeakPolarHBondContact O-CD1 3.35Å; S481-Y485 PolarHBondContact O-N 3.45Å
482Q98.2Very high96.6Very high118 Ų11850 Ų5055%0.55126%0.264SS*.Hα-helixtrans-58.9-39.8178.4-1755750.100112.5G480 L484 Y485 D486G480-Q482 PolarHBondContact O-N 2.9Å; Q482-L484 VanDerWaalsContact C-N 3.33Å; Q482-Y485 WeakPolarHBondContact O-CB 3.42Å; Q482-Y485 PolarHBondContact O-N 3.31Å; Q482-D486 PolarHBondContact NE2-OD1 3.18Å; Q482-D486 VanDerWaalsContact NE2-OD1 3.15Å; Q482-D486 VanDerWaalsContact O-CG 3.24Å; Q482-D486 PolarHBondContact O-N 3.49Å
483R98.6Very high96.7Very high78 Ų7852.2 Ų52.229%0.29428%0.279SS..Hα-helixtrans-72.7-28.5177.5-73.2-177.668.6-167.57.7112.1R420 Q423 I479 G480 S481 A487R420-R483 PolarHBondContact O-NH2 2.9Å; Q423-R483 PolarHBondContact NE2-O 3.36Å; I479-R483 HydrophobicContact CG2-CB 3.43Å; I479-R483 VanDerWaalsContact CG2-CB 3.43Å; I479-R483 HydrophobicContact CG2-CG 4.38Å; G480-R483 PolarHBondContact O-N 3.23Å; S481-R483 VanDerWaalsContact C-N 3.28Å; S481-R483 PolarHBondContact O-N 3.42Å; R483-A487 PolarHBondContact O-N 2.96Å
484L98.8Very high97Very high7 Ų746.5 Ų46.54%0.03724%0.242CC..Hα-helixtrans-67.3-40.9169.5-53.8-179.5000110.4L462 V465 M466 I479 G480 S481 Q482 D486 A487 V488 F545L462-L484 HydrophobicContact CD1-CB 4.15Å; L462-L484 HydrophobicContact CD1-CD2 3.9Å; V465-L484 HydrophobicContact CG1-CD2 3.83Å; M466-L484 HydrophobicContact CG-CD1 4.49Å; I479-L484 HydrophobicContact CB-CD2 4.34Å; I479-L484 HydrophobicContact CG2-CD2 3.96Å; I479-L484 HydrophobicContact CG2-CG 4.45Å; G480-L484 PolarHBondContact O-N 3.36Å; S481-L484 WeakPolarHBondContact O-CA 3.28Å; S481-L484 WeakPolarHBondContact O-CB 3.45Å; S481-L484 PolarHBondContact O-N 3.25Å; Q482-L484 VanDerWaalsContact C-N 3.33Å; L484-D486 VanDerWaalsContact C-N 3.32Å; L484-D486 PolarHBondContact O-N 3.46Å; L484-A487 WeakPolarHBondContact O-CB 3.22Å; L484-A487 PolarHBondContact O-N 2.93Å; L484-V488 WeakPolarHBondContact O-CG2 3.15Å; L484-V488 PolarHBondContact O-N 3.26Å; L484-F545 HydrophobicContact CB-CE2 4.27Å
485Y98.8Very high97.3Very high50 Ų5048.1 Ų48.120%0.19624%0.24CC..Hα-helixtrans-63.9-38.5176.1-58.1-12.8000111.5S481 Q482 A487 V488 N489 F545 H549 H552S481-Y485 WeakPolarHBondContact O-CD1 3.35Å; S481-Y485 PolarHBondContact O-N 3.45Å; Q482-Y485 WeakPolarHBondContact O-CB 3.42Å; Q482-Y485 PolarHBondContact O-N 3.31Å; Y485-A487 VanDerWaalsContact C-N 3.34Å; Y485-A487 PolarHBondContact O-N 3.42Å; Y485-V488 PolarHBondContact O-N 3.32Å; Y485-N489 WeakPolarHBondContact O-CB 3.41Å; Y485-N489 PolarHBondContact O-N 3.16Å; Y485-N489 PolarHBondContact O-ND2 3.26Å; Y485-F545 AromaticContact CD1-CE2 3.68Å; Y485-F545 HydrophobicContact CD1-CE2 3.68Å; Y485-F545 AromaticContact CD1-CZ 3.42Å; Y485-F545 HydrophobicContact CD1-CZ 3.42Å; Y485-F545 VanDerWaalsContact CD1-CZ 3.42Å; Y485-F545 AromaticContact CE1-CE2 3.87Å; Y485-F545 HydrophobicContact CE1-CE2 3.87Å; Y485-F545 AromaticContact CE1-CZ 3.55Å; Y485-F545 HydrophobicContact CE1-CZ 3.55Å; Y485-H549 HydrophobicContact CE1-CB 4.39Å; Y485-H549 AromaticContact CE1-CG 3.96Å; Y485-H549 AromaticContact CE1-ND1 3.86Å; Y485-H549 PolarHBondContact OH-ND1 2.78Å; Y485-H552 AromaticContact CD1-CD2 3.95Å; Y485-H552 AromaticContact CD1-CG 3.95Å; Y485-H552 AromaticContact CD2-CE1 3.52Å; Y485-H552 AromaticContact CD2-ND1 3.64Å; Y485-H552 HydrophobicContact CE1-CB 4.21Å; Y485-H552 AromaticContact CE1-CG 3.96Å; Y485-H552 AromaticContact CE2-ND1 3.69Å; Y485-H552 AromaticContact CG-CE1 3.51Å; Y485-H552 AromaticContact CG-ND1 3.81Å; Y485-H552 AromaticContact CG-NE2 3.73Å; Y485-H552 AromaticContact CZ-ND1 3.92Å
486D98.9Very high97.4Very high26 Ų2648.3 Ų48.314%0.13924%0.241CC..Hα-helixtrans-61.7-41.3175.4-65.4-19.8000111.6Q482 L484 N489 V490Q482-D486 PolarHBondContact NE2-OD1 3.18Å; Q482-D486 VanDerWaalsContact NE2-OD1 3.15Å; Q482-D486 VanDerWaalsContact O-CG 3.24Å; Q482-D486 PolarHBondContact O-N 3.49Å; L484-D486 VanDerWaalsContact C-N 3.32Å; L484-D486 PolarHBondContact O-N 3.46Å; D486-N489 WeakPolarHBondContact O-CB 3.39Å; D486-N489 PolarHBondContact O-N 3.18Å; D486-V490 PolarHBondContact O-N 2.8Å
487A98.9Very high98.1Very high0 Ų050 Ų500%025%0.247CC..Hα-helixtrans-62.2-43.3173.300000112.4G441 T458 L462 R483 L484 Y485 N489 V490 L491G441-A487 VanDerWaalsContact O-CA 3.32Å; G441-A487 WeakPolarHBondContact O-CA 3.15Å; G441-A487 VanDerWaalsContact O-CB 3.23Å; G441-A487 WeakPolarHBondContact O-CB 3.5Å; T458-A487 HydrophobicContact CG2-CB 4.23Å; L462-A487 HydrophobicContact CB-CB 4.43Å; L462-A487 HydrophobicContact CD1-CB 4.22Å; L462-A487 HydrophobicContact CD2-CB 4.36Å; R483-A487 PolarHBondContact O-N 2.96Å; L484-A487 WeakPolarHBondContact O-CB 3.22Å; L484-A487 PolarHBondContact O-N 2.93Å; Y485-A487 VanDerWaalsContact C-N 3.34Å; Y485-A487 PolarHBondContact O-N 3.42Å; A487-N489 VanDerWaalsContact C-N 3.29Å; A487-N489 PolarHBondContact O-N 3.24Å; A487-V490 WeakPolarHBondContact O-CB 3.45Å; A487-V490 PolarHBondContact O-N 3.06Å; A487-L491 PolarHBondContact O-N 2.98Å
488V98.9Very high98.4Very high0 Ų046.5 Ų46.50%023%0.232CC..Hα-helixtrans-61.6-38.81741710000111.2L462 L484 Y485 V490 L491 L492 L542 F545 I557L462-V488 HydrophobicContact CD2-CG2 3.71Å; L484-V488 WeakPolarHBondContact O-CG2 3.15Å; L484-V488 PolarHBondContact O-N 3.26Å; Y485-V488 PolarHBondContact O-N 3.32Å; V488-V490 VanDerWaalsContact C-N 3.34Å; V488-V490 PolarHBondContact O-N 2.99Å; V488-L491 PolarHBondContact O-N 2.99Å; V488-L492 HydrophobicContact CG1-CD1 3.77Å; V488-L492 HydrophobicContact CG1-CG 4.13Å; V488-L492 WeakPolarHBondContact O-CG 3.41Å; V488-L492 PolarHBondContact O-N 2.81Å; V488-L542 HydrophobicContact CB-CD2 4.49Å; V488-L542 HydrophobicContact CG1-CD2 3.92Å; V488-L542 HydrophobicContact CG2-CD2 4.25Å; V488-F545 HydrophobicContact CG1-CE1 4.37Å; V488-F545 HydrophobicContact CG2-CB 4.41Å; V488-F545 HydrophobicContact CG2-CD1 3.8Å; V488-F545 HydrophobicContact CG2-CD2 3.6Å; V488-F545 HydrophobicContact CG2-CE1 3.92Å; V488-F545 HydrophobicContact CG2-CE2 3.72Å; V488-F545 HydrophobicContact CG2-CG 3.64Å; V488-F545 HydrophobicContact CG2-CZ 3.88Å; V488-I557 HydrophobicContact CG1-CD1 4.19Å
489N98.8Very high98.5Very high42 Ų4243.3 Ų43.323%0.22521%0.213CC..Hα-helixtrans-64.1-38.3177.3-68.7-29.9000112M438 Y485 D486 A487 S493 R553M438-N489 HydrophobicContact CE-CB 4.28Å; M438-N489 WeakPolarHBondContact CE-O 3.39Å; Y485-N489 WeakPolarHBondContact O-CB 3.41Å; Y485-N489 PolarHBondContact O-N 3.16Å; Y485-N489 PolarHBondContact O-ND2 3.26Å; D486-N489 WeakPolarHBondContact O-CB 3.39Å; D486-N489 PolarHBondContact O-N 3.18Å; A487-N489 VanDerWaalsContact C-N 3.29Å; A487-N489 PolarHBondContact O-N 3.24Å; N489-S493 WeakPolarHBondContact O-CB 3.14Å; N489-S493 PolarHBondContact O-N 3.46Å; N489-R553 PolarHBondContact OD1-NH1 3.13Å
490V98.9Very high98.5Very high0 Ų043 Ų430%021%0.212CC..Hα-helixtrans-58.8-53.4172171.40000110.1M438 K440 I453 T458 D486 A487 V488 L492 S493 M494M438-V490 HydrophobicContact CE-CG2 4.08Å; K440-V490 WeakPolarHBondContact O-CG2 3.39Å; I453-V490 HydrophobicContact CD1-CG1 3.82Å; I453-V490 HydrophobicContact CG1-CG1 4.34Å; T458-V490 HydrophobicContact CG2-CB 4.44Å; T458-V490 HydrophobicContact CG2-CG1 4.32Å; D486-V490 PolarHBondContact O-N 2.8Å; A487-V490 WeakPolarHBondContact O-CB 3.45Å; A487-V490 PolarHBondContact O-N 3.06Å; V488-V490 VanDerWaalsContact C-N 3.34Å; V488-V490 PolarHBondContact O-N 2.99Å; V490-L492 PolarHBondContact O-N 2.81Å; V490-S493 WeakPolarHBondContact O-CB 3.43Å; V490-S493 PolarHBondContact O-N 2.93Å; V490-S493 VanDerWaalsContact O-N 3.13Å; V490-S493 PolarHBondContact O-OG 3.24Å; V490-M494 HydrophobicContact CG1-SD 3.88Å; V490-M494 WeakPolarHBondContact O-CG 3.24Å; V490-M494 PolarHBondContact O-N 2.92Å
491L98.9Very high98.6Very high0 Ų040.9 Ų40.90%019%0.19CC..Hα-helixtrans-57.7-50.5178.9-63.7177.7000111.7A455 T458 A459 L462 A487 V488 S493 M494 F501 L542A455-L491 HydrophobicContact CB-CD2 4.45Å; A455-L491 VanDerWaalsContact O-CD2 3.24Å; A455-L491 WeakPolarHBondContact O-CD2 3.24Å; T458-L491 HydrophobicContact CG2-CD2 4.03Å; T458-L491 HydrophobicContact CG2-CG 4.05Å; A459-L491 HydrophobicContact CB-CD1 4.25Å; A459-L491 HydrophobicContact CB-CD2 4.36Å; L462-L491 HydrophobicContact CD2-CD1 4.45Å; A487-L491 PolarHBondContact O-N 2.98Å; V488-L491 PolarHBondContact O-N 2.99Å; L491-S493 PolarHBondContact O-N 3.29Å; L491-M494 PolarHBondContact O-N 2.85Å; L491-F501 HydrophobicContact CB-CE1 4.34Å; L491-F501 WeakPolarHBondContact O-CE1 3.49Å; L491-L542 HydrophobicContact CB-CD2 4.46Å; L491-L542 HydrophobicContact CD1-CD2 4.1Å; L491-L542 HydrophobicContact CD1-CG 4.14Å
492L98.9Very high98.7Very high8 Ų838.3 Ų38.34%0.04217%0.172CC..Hα-helixtrans-62.4-28-179.9-66.4178.1000112.9V488 V490 M494 R495 L542 R553 E556 I557 T560V488-L492 HydrophobicContact CG1-CD1 3.77Å; V488-L492 HydrophobicContact CG1-CG 4.13Å; V488-L492 WeakPolarHBondContact O-CG 3.41Å; V488-L492 PolarHBondContact O-N 2.81Å; V490-L492 PolarHBondContact O-N 2.81Å; L492-M494 PolarHBondContact O-N 3.24Å; L492-R495 WeakPolarHBondContact O-CD 3.48Å; L492-R495 WeakPolarHBondContact O-CG 3.44Å; L492-L542 HydrophobicContact CD2-CD1 4.36Å; L492-R553 HydrophobicContact CD1-CB 4.32Å; L492-R553 VanDerWaalsContact CD1-CZ 3.43Å; L492-E556 HydrophobicContact CD1-CG 4.47Å; L492-E556 HydrophobicContact CD2-CG 4.26Å; L492-I557 HydrophobicContact CD1-CG1 4.22Å; L492-I557 HydrophobicContact CD2-CG1 4.33Å; L492-T560 HydrophobicContact CD2-CG2 4.43Å
493S98.8Very high98.7Very high47 Ų4732.9 Ų32.933%0.32915%0.146SC..Hα-helixtrans-73-12.7173.581.30000114.3Q437 N489 V490 L491Q437-S493 PolarHBondContact NE2-O 3.02Å; Q437-S493 PolarHBondContact NE2-OG 2.94Å; N489-S493 WeakPolarHBondContact O-CB 3.14Å; N489-S493 PolarHBondContact O-N 3.46Å; V490-S493 WeakPolarHBondContact O-CB 3.43Å; V490-S493 PolarHBondContact O-N 2.93Å; V490-S493 VanDerWaalsContact O-N 3.13Å; V490-S493 PolarHBondContact O-OG 3.24Å; L491-S493 PolarHBondContact O-N 3.29Å
494M98.9Very high98.7Very high0 Ų030.2 Ų30.20%014%0.137CC..THydrogen-bonded Turntrans-10410.1-176.6-64.2174.275.100113.6Q437 I453 A455 V490 L491 L492 N496 F501 T503 Y504 E505Q437-M494 HydrophobicContact CG-CG 4.08Å; Q437-M494 HydrophobicContact CG-SD 4.35Å; I453-M494 HydrophobicContact CD1-CE 4.37Å; I453-M494 HydrophobicContact CD1-SD 3.96Å; A455-M494 HydrophobicContact CB-CE 3.74Å; A455-M494 HydrophobicContact CB-SD 4.25Å; V490-M494 HydrophobicContact CG1-SD 3.88Å; V490-M494 WeakPolarHBondContact O-CG 3.24Å; V490-M494 PolarHBondContact O-N 2.92Å; L491-M494 PolarHBondContact O-N 2.85Å; L492-M494 PolarHBondContact O-N 3.24Å; M494-N496 PolarHBondContact O-ND2 3.48Å; M494-F501 HydrophobicContact CB-CD1 4.26Å; M494-F501 HydrophobicContact CB-CE1 4.35Å; M494-T503 WeakPolarHBondContact CE-O 3.49Å; M494-Y504 WeakPolarHBondContact CE-O 3.39Å; M494-E505 WeakPolarHBondContact CE-O 3.22Å
495R98.8Very high98.8Very high87 Ų8730 Ų3033%0.32814%0.135SC..  trans-61.2142.7174.4-68170.866.1-163.43.5111.4L492 F501 E556 T560 D563L492-R495 WeakPolarHBondContact O-CD 3.48Å; L492-R495 WeakPolarHBondContact O-CG 3.44Å; R495-F501 HydrophobicContact CG-CZ 4.16Å; R495-E556 IonicContact NH1-OE1 2.8Å; R495-T560 WeakPolarHBondContact CD-OG1 3.34Å; R495-T560 HydrophobicContact CG-CG2 4.14Å; R495-T560 PolarHBondContact NE-OG1 3.29Å; R495-D563 IonicContact NH2-OD2 3.93Å; R495-D563 PolarHBondContact NH2-OD2 2.62Å
496N98.8Very high98.8Very high24 Ų2429 Ų2913%0.12814%0.135CC..  trans-115.9161176.5-63.5-81.9000112.1M494 D498 G499 G500 T506 K507 T530M494-N496 PolarHBondContact O-ND2 3.48Å; N496-D498 WeakPolarHBondContact CB-OD1 3.36Å; N496-D498 PolarHBondContact O-N 2.87Å; N496-G499 PolarHBondContact O-N 2.71Å; N496-G500 WeakPolarHBondContact CB-O 2.81Å; N496-G500 PolarHBondContact ND2-O 2.95Å; N496-T506 WeakPolarHBondContact OD1-CB 3.23Å; N496-K507 PolarHBondContact OD1-N 3.12Å; N496-T530 HydrophobicContact CB-CG2 3.92Å
497R98Very high98.7Very high265 Ų26530 Ų30100%114%0.137SC*.THydrogen-bonded Turntrans-61.3-25.2-179.4-68.3-175.6179.7-179.40.6113.9G499R497-G499 VanDerWaalsContact C-N 3.34Å
498D98.4Very high98.7Very high41 Ų4133.3 Ų33.322%0.21915%0.15CC..THydrogen-bonded Turntrans-9514.3176.866.4-18.2000113N496 G500 K507 T530 F567 R570N496-D498 WeakPolarHBondContact CB-OD1 3.36Å; N496-D498 PolarHBondContact O-N 2.87Å; D498-G500 PolarHBondContact O-N 3.41Å; D498-G500 VanDerWaalsContact O-N 3.12Å; D498-K507 VanDerWaalsContact CG-NZ 3.34Å; D498-K507 IonicContact OD1-NZ 2.78Å; D498-K507 IonicContact OD2-NZ 3.31Å; D498-K507 PolarHBondContact OD2-NZ 2.8Å; D498-T530 PolarHBondContact OD2-OG1 3.08Å; D498-T530 VanDerWaalsContact OD2-OG1 3.06Å; D498-F567 WeakPolarHBondContact O-CB 3.14Å; D498-F567 WeakPolarHBondContact O-CD2 3.39Å; D498-R570 PolarHBondContact O-NH2 2.87Å
499G98.6Very high98.7Very high11 Ų1133.9 Ų33.911%0.11316%0.156CC..SBendtrans76.1-1217600000115.4N496 R497 G564N496-G499 PolarHBondContact O-N 2.71Å; R497-G499 VanDerWaalsContact C-N 3.34Å; G499-G564 WeakPolarHBondContact O-CA 3.17Å
500G98.7Very high98.6Very high0 Ų034.2 Ų34.20%017%0.169CC..  trans-82.4165179.200000113.3N496 D498 T535N496-G500 WeakPolarHBondContact CB-O 2.81Å; N496-G500 PolarHBondContact ND2-O 2.95Å; D498-G500 PolarHBondContact O-N 3.41Å; D498-G500 VanDerWaalsContact O-N 3.12Å; G500-T535 WeakPolarHBondContact CA-OG1 3.45Å
501F98.9Very high98.5Very high1 Ų141 Ų410%0.00420%0.199CC..BIsolated β-bridgetrans-107.2139.4170.6-77.2-104.8000110.1A455 L491 M494 R495 T530 Y531 C534 T535 A538 T560A455-F501 HydrophobicContact CB-CB 4.43Å; A455-F501 HydrophobicContact CB-CD1 4.18Å; L491-F501 HydrophobicContact CB-CE1 4.34Å; L491-F501 WeakPolarHBondContact O-CE1 3.49Å; M494-F501 HydrophobicContact CB-CD1 4.26Å; M494-F501 HydrophobicContact CB-CE1 4.35Å; R495-F501 HydrophobicContact CG-CZ 4.16Å; F501-T530 CarbonylContact O-C 3.15Å; F501-T530 VanDerWaalsContact O-CA 3.27Å; F501-T530 WeakPolarHBondContact O-CA 3.42Å; F501-Y531 PolarHBondContact O-N 2.9Å; F501-C534 HydrophobicContact CB-CB 4.13Å; F501-T535 HydrophobicContact CD2-CG2 4.31Å; F501-T535 PolarHBondContact N-OG1 3.02Å; F501-A538 HydrophobicContact CD1-CB 3.95Å; F501-A538 HydrophobicContact CD2-CB 3.95Å; F501-A538 HydrophobicContact CE1-CB 3.98Å; F501-A538 HydrophobicContact CE2-CB 4.01Å; F501-A538 HydrophobicContact CG-CB 3.92Å; F501-A538 HydrophobicContact CZ-CB 4.02Å; F501-T560 HydrophobicContact CE2-CG2 3.72Å; F501-T560 HydrophobicContact CZ-CG2 3.69Å
502A98.8Very high98.5Very high0 Ų047.6 Ų47.60%023%0.233CC..  trans-92.5-165.4172.800000110.2A455 D528 Y529 T530 C534A455-A502 WeakPolarHBondContact CB-O 3.46Å; A502-D528 HydrophobicContact CB-CB 4.14Å; A502-D528 WeakPolarHBondContact CB-OD1 3.44Å; A502-Y529 WeakPolarHBondContact CA-O 3.24Å; A502-Y529 WeakPolarHBondContact CB-O 3.26Å; A502-T530 HydrophobicContact CB-CG2 4.39Å; A502-C534 WeakPolarHBondContact O-CB 3.36Å
503T98.8Very high98.5Very high3 Ų348.1 Ų48.12%0.01824%0.236CC..SBendtrans-83.9-90.1-179.455.90000112.7W231 V454 A455 M494 D528 Y531 W582W231-T503 PolarHBondContact NE1-OG1 2.86Å; V454-T503 CarbonylContact C-O 3.49Å; V454-T503 WeakPolarHBondContact CA-O 3.37Å; V454-T503 VanDerWaalsContact CG1-C 3.49Å; V454-T503 VanDerWaalsContact CG1-O 3.31Å; V454-T503 WeakPolarHBondContact CG1-O 3.48Å; A455-T503 PolarHBondContact N-O 2.92Å; M494-T503 WeakPolarHBondContact CE-O 3.49Å; T503-D528 PolarHBondContact N-OD1 3.45Å; T503-D528 VanDerWaalsContact OG1-CG 3.23Å; T503-D528 PolarHBondContact OG1-OD1 3.38Å; T503-D528 PolarHBondContact OG1-OD2 3.1Å; T503-Y531 HydrophobicContact CG2-CD2 4.09Å; T503-Y531 HydrophobicContact CG2-CE2 3.99Å; T503-W582 HydrophobicContact CG2-CH2 3.93Å; T503-W582 HydrophobicContact CG2-CZ2 3.26Å
504Y98.8Very high98.5Very high23 Ų2347.4 Ų47.49%0.0923%0.227CC..SBendtrans-85.6-24.6-172.1-66.1-98.3000112.1C232 H233 I336 W452 I453 V454 M494 D528C232-Y504 VanDerWaalsContact SG-CB 3.56Å; C232-Y504 WeakPolarHBondContact SG-CD2 3.32Å; C232-Y504 VanDerWaalsContact SG-CG 3.52Å; H233-Y504 AromaticContact CD2-CE2 3.53Å; H233-Y504 AromaticContact NE2-CE2 3.34Å; H233-Y504 VanDerWaalsContact NE2-CE2 3.34Å; H233-Y504 WeakPolarHBondContact NE2-CE2 3.47Å; H233-Y504 AromaticContact NE2-CZ 3.39Å; H233-Y504 PolarHBondContact NE2-OH 2.69Å; I336-Y504 HydrophobicContact CD1-CD1 4.03Å; I336-Y504 HydrophobicContact CD1-CD2 4.41Å; I336-Y504 HydrophobicContact CD1-CE1 3.88Å; I336-Y504 HydrophobicContact CD1-CE2 4.31Å; I336-Y504 HydrophobicContact CD1-CG 4.3Å; I336-Y504 HydrophobicContact CG1-CE1 4Å; W452-Y504 HydrophobicContact CB-CD1 4.01Å; W452-Y504 HydrophobicContact CB-CE1 3.93Å; W452-Y504 HydrophobicContact CE3-CD1 4.2Å; I453-Y504 WeakPolarHBondContact O-CA 3.49Å; I453-Y504 WeakPolarHBondContact O-CD1 2.97Å; V454-Y504 HydrophobicContact CG2-CD1 3.83Å; V454-Y504 HydrophobicContact CG2-CE1 3.55Å; V454-Y504 HydrophobicContact CG2-CG 4.43Å; M494-Y504 WeakPolarHBondContact CE-O 3.39Å; Y504-D528 PolarHBondContact N-OD2 2.84Å; Y504-D528 VanDerWaalsContact N-OD2 3.14Å
505E98.8Very high98.4Very high1 Ų151.1 Ų51.11%0.00525%0.247CC..SBendtrans-139.4-149-170.1-49.6-169.5126.900111.2R235 Q437 M494 R508 D528R235-E505 IonicContact CZ-OE1 3.88Å; R235-E505 IonicContact CZ-OE2 3.41Å; R235-E505 VanDerWaalsContact CZ-OE2 3.27Å; R235-E505 IonicContact NH1-OE1 2.68Å; R235-E505 IonicContact NH1-OE2 3.31Å; R235-E505 PolarHBondContact NH1-OE2 3.22Å; R235-E505 IonicContact NH2-OE1 3.24Å; R235-E505 PolarHBondContact NH2-OE1 3.01Å; R235-E505 IonicContact NH2-OE2 3.08Å; R235-E505 PolarHBondContact NH2-OE2 3.45Å; Q437-E505 HydrophobicContact CB-CG 4.13Å; M494-E505 WeakPolarHBondContact CE-O 3.22Å; E505-R508 IonicContact OE1-CZ 3Å; E505-R508 VanDerWaalsContact OE1-CZ 3.31Å; E505-R508 IonicContact OE1-NH1 2.62Å; E505-R508 PolarHBondContact OE1-NH1 3.3Å; E505-R508 IonicContact OE1-NH2 3.06Å; E505-R508 PolarHBondContact OE1-NH2 2.79Å; E505-R508 IonicContact OE2-CZ 3.57Å; E505-R508 VanDerWaalsContact OE2-CZ 3.24Å; E505-R508 IonicContact OE2-NE 3.28Å; E505-R508 IonicContact OE2-NH1 2.74Å; E505-R508 PolarHBondContact OE2-NH1 3.44Å; E505-R508 IonicContact OE2-NH2 3.47Å; E505-R508 PolarHBondContact OE2-NH2 2.83Å; E505-D528 PolarHBondContact N-OD2 2.64Å
506T98.8Very high98.4Very high30 Ų3048.9 Ų48.918%0.18424%0.241CC..  trans-108.5164.5170.353.30000109.6N496 R508N496-T506 WeakPolarHBondContact OD1-CB 3.23Å; T506-R508 VanDerWaalsContact C-N 3.26Å; T506-R508 WeakPolarHBondContact O-CG 3.35Å; T506-R508 PolarHBondContact O-N 2.83Å
507K98.5Very high98.4Very high46 Ų4647.9 Ų47.920%0.224%0.236CC..  trans-7383.1170.7-172.9166.760.3-155.50110.1N496 D498 I527 D528 T530N496-K507 PolarHBondContact OD1-N 3.12Å; D498-K507 VanDerWaalsContact CG-NZ 3.34Å; D498-K507 IonicContact OD1-NZ 2.78Å; D498-K507 IonicContact OD2-NZ 3.31Å; D498-K507 PolarHBondContact OD2-NZ 2.8Å; K507-I527 HydrophobicContact CD-CD1 3.98Å; K507-I527 HydrophobicContact CG-CD1 3.97Å; K507-D528 VanDerWaalsContact CA-O 3.31Å; K507-D528 WeakPolarHBondContact CA-O 3.47Å; K507-D528 VanDerWaalsContact CB-O 3.28Å; K507-D528 WeakPolarHBondContact CB-O 3.49Å; K507-T530 HydrophobicContact CB-CG2 4.43Å; K507-T530 PolarHBondContact NZ-OG1 2.99Å
508R98.5Very high98.4Very high71 Ų7135.8 Ų35.827%0.26819%0.192SC..  trans-75.8-30.6-174.5-67173.3-174.2170.95.7113.3S228 T229 Y435 E505 T506S228-R508 WeakPolarHBondContact O-CD 3.46Å; S228-R508 PolarHBondContact O-NH1 2.76Å; T229-R508 HydrophobicContact CG2-CB 4.48Å; Y435-R508 PolarHBondContact O-NH1 2.88Å; Y435-R508 PolarHBondContact O-NH2 3.16Å; E505-R508 IonicContact OE1-CZ 3Å; E505-R508 VanDerWaalsContact OE1-CZ 3.31Å; E505-R508 IonicContact OE1-NH1 2.62Å; E505-R508 PolarHBondContact OE1-NH1 3.3Å; E505-R508 IonicContact OE1-NH2 3.06Å; E505-R508 PolarHBondContact OE1-NH2 2.79Å; E505-R508 IonicContact OE2-CZ 3.57Å; E505-R508 VanDerWaalsContact OE2-CZ 3.24Å; E505-R508 IonicContact OE2-NE 3.28Å; E505-R508 IonicContact OE2-NH1 2.74Å; E505-R508 PolarHBondContact OE2-NH1 3.44Å; E505-R508 IonicContact OE2-NH2 3.47Å; E505-R508 PolarHBondContact OE2-NH2 2.83Å; T506-R508 VanDerWaalsContact C-N 3.26Å; T506-R508 WeakPolarHBondContact O-CG 3.35Å; T506-R508 PolarHBondContact O-N 2.83Å
509G97.8Very high98.4Very high12 Ų1233.9 Ų33.912%0.12418%0.181CC..SBendtrans-103.7162.5179.100000113.8T229T229-G509 PolarHBondContact O-N 2.76Å
510G97.2Very high98.4Very high48 Ų4833.5 Ų33.550%0.49518%0.177SC..  trans-82.8151.7174.200000112.7L512 L513G510-L512 PolarHBondContact O-N 2.71Å; G510-L512 VanDerWaalsContact O-N 3.08Å; G510-L513 WeakPolarHBondContact O-CB 3.39Å; G510-L513 WeakPolarHBondContact O-CG 3.42Å; G510-L513 PolarHBondContact O-N 3.35Å
511K97.8Very high98.3Very high143 Ų14333.7 Ų33.762%0.62218%0.178SC*.G310 helixtrans-56.3-27.2-178.6-65.8-173.6177.6-173.90114.5L513 E514 I527 Y529K511-L513 PolarHBondContact O-N 2.69Å; K511-L513 VanDerWaalsContact O-N 3.16Å; K511-E514 WeakPolarHBondContact O-CB 3.25Å; K511-E514 PolarHBondContact O-N 3.23Å; K511-E514 VanDerWaalsContact O-N 3.15Å; K511-I527 HydrophobicContact CG-CD1 4.34Å; K511-Y529 HydrophobicContact CG-CE1 4.47Å
512L98.3Very high98.3Very high138 Ų13834 Ų3472%0.72318%0.179SC*.G310 helixtrans-63-18.1177.5-66.7178.4000113.2G510 E514 L515G510-L512 PolarHBondContact O-N 2.71Å; G510-L512 VanDerWaalsContact O-N 3.08Å; L512-E514 PolarHBondContact O-N 3.25Å; L512-L515 HydrophobicContact CD2-CD1 4.26Å; L512-L515 VanDerWaalsContact O-CB 3.32Å; L512-L515 WeakPolarHBondContact O-CB 3.11Å; L512-L515 WeakPolarHBondContact O-CG 3.37Å; L512-L515 PolarHBondContact O-N 3.06Å; L512-L515 VanDerWaalsContact O-N 3.13Å
513L98.4Very high98.2Very high19 Ų1934.2 Ų34.210%0.09918%0.181CC..G310 helixtrans-63.1-21.8174.8-66.8178000112.7A225 L230 G510 K511 L515 L516 M526 I527A225-L513 HydrophobicContact CB-CD2 3.77Å; L230-L513 HydrophobicContact CD2-CD1 4.16Å; G510-L513 WeakPolarHBondContact O-CB 3.39Å; G510-L513 WeakPolarHBondContact O-CG 3.42Å; G510-L513 PolarHBondContact O-N 3.35Å; K511-L513 PolarHBondContact O-N 2.69Å; K511-L513 VanDerWaalsContact O-N 3.16Å; L513-L515 PolarHBondContact O-N 3.32Å; L513-L516 HydrophobicContact CD2-CD1 4.23Å; L513-L516 WeakPolarHBondContact O-CB 3.35Å; L513-L516 PolarHBondContact O-N 3.34Å; L513-M526 HydrophobicContact CB-CB 4.2Å; L513-M526 WeakPolarHBondContact O-CG 3.4Å; L513-I527 HydrophobicContact CB-CG2 4.11Å; L513-I527 HydrophobicContact CD1-CG2 3.75Å; L513-I527 HydrophobicContact CG-CG2 4.49Å
514E98.5Very high98.2Very high32 Ų3235.8 Ų35.815%0.1519%0.19CC..G310 helixtrans-62.8-23.7174.7-160.256.6-144.400112.9K511 L512 L516 N517 D524 I525 M526 Y529K511-E514 WeakPolarHBondContact O-CB 3.25Å; K511-E514 PolarHBondContact O-N 3.23Å; K511-E514 VanDerWaalsContact O-N 3.15Å; L512-E514 PolarHBondContact O-N 3.25Å; E514-L516 PolarHBondContact O-N 3.25Å; E514-L516 VanDerWaalsContact O-N 3.09Å; E514-N517 VanDerWaalsContact O-CB 3.25Å; E514-N517 WeakPolarHBondContact O-CB 3.29Å; E514-N517 PolarHBondContact O-N 2.97Å; E514-N517 WeakPolarHBondContact OE1-CB 3.47Å; E514-N517 PolarHBondContact OE1-ND2 3.21Å; E514-D524 VanDerWaalsContact CD-CA 3.43Å; E514-D524 VanDerWaalsContact OE1-CA 3.28Å; E514-D524 WeakPolarHBondContact OE1-CA 3.24Å; E514-D524 PolarHBondContact OE1-N 2.86Å; E514-D524 WeakPolarHBondContact OE2-CA 3.18Å; E514-I525 PolarHBondContact OE1-N 2.98Å; E514-I525 PolarHBondContact OE2-N 3Å; E514-M526 WeakPolarHBondContact OE2-CB 3.15Å; E514-M526 PolarHBondContact OE2-N 3.4Å; E514-Y529 WeakPolarHBondContact CB-OH 3.45Å; E514-Y529 WeakPolarHBondContact CG-OH 3.41Å; E514-Y529 PolarHBondContact OE2-OH 2.71Å
515L98.4Very high98.1Very high78 Ų7835 Ų3541%0.40819%0.187SC..G310 helixtrans-62.5-15.9171.8-63.1174.8000112.3S291 L293 L294 L512 L513S291-L515 WeakPolarHBondContact CB-O 3.38Å; S291-L515 PolarHBondContact OG-O 3.06Å; L293-L515 HydrophobicContact CB-CB 4.42Å; L293-L515 HydrophobicContact CD2-CB 3.92Å; L293-L515 HydrophobicContact CD2-CD1 4.16Å; L294-L515 WeakPolarHBondContact CB-O 3.32Å; L512-L515 HydrophobicContact CD2-CD1 4.26Å; L512-L515 VanDerWaalsContact O-CB 3.32Å; L512-L515 WeakPolarHBondContact O-CB 3.11Å; L512-L515 WeakPolarHBondContact O-CG 3.37Å; L512-L515 PolarHBondContact O-N 3.06Å; L512-L515 VanDerWaalsContact O-N 3.13Å; L513-L515 PolarHBondContact O-N 3.32Å
516L98.4Very high98.1Very high40 Ų4035.5 Ų35.521%0.20919%0.189CC..G310 helixtrans-999.4176.8-56.6177.3000113.1A225 L293 L294 L513 E514 P518 M526A225-L516 HydrophobicContact CB-CD1 3.86Å; L293-L516 HydrophobicContact CD2-CD2 3.92Å; L293-L516 HydrophobicContact CD2-CG 4.47Å; L293-L516 HydrophobicContact CG-CD2 3.93Å; L294-L516 HydrophobicContact CD1-CD2 4.4Å; L513-L516 HydrophobicContact CD2-CD1 4.23Å; L513-L516 WeakPolarHBondContact O-CB 3.35Å; L513-L516 PolarHBondContact O-N 3.34Å; E514-L516 PolarHBondContact O-N 3.25Å; E514-L516 VanDerWaalsContact O-N 3.09Å; L516-P518 WeakPolarHBondContact O-CD 3.25Å; L516-P518 VanDerWaalsContact O-N 3.15Å; L516-M526 HydrophobicContact CB-CE 4.04Å
517N98.6Very high98.1Very high3 Ų334.1 Ų34.12%0.01618%0.181CC..  trans-61.3111.5176.8178.5-8.8000110.8T288 L294 E514 S519 F522 I525 M526T288-N517 HydrophobicContact CG2-CB 4.33Å; L294-N517 WeakPolarHBondContact CD2-O 3.4Å; E514-N517 VanDerWaalsContact O-CB 3.25Å; E514-N517 WeakPolarHBondContact O-CB 3.29Å; E514-N517 PolarHBondContact O-N 2.97Å; E514-N517 WeakPolarHBondContact OE1-CB 3.47Å; E514-N517 PolarHBondContact OE1-ND2 3.21Å; N517-S519 WeakPolarHBondContact OD1-CB 3.21Å; N517-S519 PolarHBondContact OD1-N 3.04Å; N517-S519 PolarHBondContact OD1-OG 3.43Å; N517-F522 PolarHBondContact ND2-O 3.3Å; N517-I525 HydrophobicContact CB-CG1 4.41Å; N517-I525 WeakPolarHBondContact OD1-CD1 3.33Å; N517-M526 HydrophobicContact CB-CG 3.87Å; N517-M526 HydrophobicContact CB-SD 4.27Å
518P98.2Very high98.1Very high12 Ų1232 Ų328%0.07817%0.172CC..  trans-103.39.2-176.133.7-19.5000112.9S192 Y238 L294 Y298 L516 E520S192-P518 PolarHBondContact OG-O 3.39Å; Y238-P518 HydrophobicContact CE1-CG 4.28Å; L294-P518 HydrophobicContact CD2-CB 3.96Å; Y298-P518 HydrophobicContact CE2-CB 4Å; Y298-P518 WeakPolarHBondContact OH-CB 3.39Å; L516-P518 WeakPolarHBondContact O-CD 3.25Å; L516-P518 VanDerWaalsContact O-N 3.15Å; P518-E520 VanDerWaalsContact O-OE1 3.06Å
519S96.9Very high98.1Very high0 Ų030 Ų300%017%0.165CC..  trans-80.7-17.7-170.166.80000114.4N517 V521 F522 I525N517-S519 WeakPolarHBondContact OD1-CB 3.21Å; N517-S519 PolarHBondContact OD1-N 3.04Å; N517-S519 PolarHBondContact OD1-OG 3.43Å; S519-V521 PolarHBondContact O-N 2.89Å; S519-F522 PolarHBondContact OG-N 3.48Å; S519-F522 PolarHBondContact OG-O 3.32Å; S519-I525 WeakPolarHBondContact OG-CD1 3.47Å
520E98.6Very high98.2Very high4 Ų430.3 Ų30.32%0.01916%0.164CC..SBendtrans61.8-40.2-177.3-57.2100.8178.800116.4S192 V281 L286 Y287 T288 H290 P518S192-E520 WeakPolarHBondContact CB-OE2 3.2Å; S192-E520 PolarHBondContact N-OE2 3.47Å; S192-E520 PolarHBondContact OG-OE2 3.49Å; V281-E520 HydrophobicContact CG1-CB 4.39Å; V281-E520 HydrophobicContact CG2-CG 4.16Å; L286-E520 HydrophobicContact CD1-CB 3.8Å; L286-E520 HydrophobicContact CD1-CG 4.11Å; Y287-E520 PolarHBondContact N-O 2.77Å; T288-E520 PolarHBondContact N-O 2.85Å; T288-E520 WeakPolarHBondContact O-CA 3.22Å; H290-E520 IonicContact CD2-OE1 3.76Å; H290-E520 IonicContact CE1-OE1 2.85Å; H290-E520 PolarHBondContact CE1-OE1 3.38Å; H290-E520 IonicContact NE2-OE1 3.41Å; H290-E520 PolarHBondContact NE2-OE1 3.09Å; P518-E520 VanDerWaalsContact O-OE1 3.06Å
521V97.9Very high98.3Very high4 Ų429 Ų292%0.02414%0.144CC..SBendtrans-95.7-13.2-174.2-55.60000113L144 F153 P191 D285 S519 S700L144-V521 HydrophobicContact CD1-CB 4.32Å; L144-V521 HydrophobicContact CD1-CG2 4.12Å; L144-V521 HydrophobicContact CD2-CB 4.41Å; F153-V521 HydrophobicContact CD1-CG1 4.38Å; F153-V521 HydrophobicContact CE1-CG2 4.49Å; P191-V521 HydrophobicContact CB-CG1 3.74Å; P191-V521 HydrophobicContact CG-CG1 3.62Å; D285-V521 HydrophobicContact CB-CG1 4.42Å; D285-V521 WeakPolarHBondContact O-CG1 3.34Å; S519-V521 PolarHBondContact O-N 2.89Å; V521-S700 VanDerWaalsContact O-CB 3.31Å; V521-S700 WeakPolarHBondContact O-CB 3.05Å; V521-S700 PolarHBondContact O-OG 2.9Å
522F98.1Very high98.3Very high6 Ų622.5 Ų22.53%0.02612%0.117CC..  trans-120.6149.8-177-54.4-60.6000112.9F104 L144 W193 T288 N517 S519 I525 F697 N698 C701F104-F522 HydrophobicContact CE1-CE1 4.19Å; F104-F522 AromaticContact CE1-CZ 3.89Å; F104-F522 HydrophobicContact CE1-CZ 3.89Å; F104-F522 HydrophobicContact CE2-CZ 4.08Å; F104-F522 HydrophobicContact CZ-CE1 4.02Å; F104-F522 AromaticContact CZ-CZ 3.55Å; F104-F522 HydrophobicContact CZ-CZ 3.55Å; L144-F522 HydrophobicContact CD1-CE1 4.22Å; L144-F522 HydrophobicContact CD1-CZ 4.29Å; L144-F522 HydrophobicContact CD2-CE1 4.11Å; W193-F522 HydrophobicContact CD2-CE2 4.35Å; W193-F522 AromaticContact CE3-CE2 3.94Å; W193-F522 HydrophobicContact CE3-CE2 3.94Å; W193-F522 AromaticContact CH2-CE2 3.86Å; W193-F522 HydrophobicContact CH2-CE2 3.86Å; W193-F522 HydrophobicContact CZ2-CE2 4.28Å; W193-F522 AromaticContact CZ3-CE2 3.65Å; W193-F522 HydrophobicContact CZ3-CE2 3.65Å; W193-F522 HydrophobicContact CZ3-CZ 4.24Å; T288-F522 PolarHBondContact OG1-O 3.42Å; N517-F522 PolarHBondContact ND2-O 3.3Å; S519-F522 PolarHBondContact OG-N 3.48Å; S519-F522 PolarHBondContact OG-O 3.32Å; F522-I525 HydrophobicContact CB-CG2 3.61Å; F522-F697 HydrophobicContact CE1-CE2 4.19Å; F522-N698 HydrophobicContact CB-CB 3.95Å; F522-N698 HydrophobicContact CD1-CB 4.28Å; F522-N698 HydrophobicContact CG-CB 4.4Å; F522-C701 HydrophobicContact CD1-CB 4.44Å; F522-C701 HydrophobicContact CE1-CB 3.94Å
523G97.5Very high98.3Very high5 Ų516 Ų165%0.0528%0.083CC..SBendtrans-112.8150.4173.200000113.2N698G523-N698 PolarHBondContact N-O 3.2Å; G523-N698 CarbonylContact O-C 3.57Å; G523-N698 WeakPolarHBondContact O-CA 3.36Å; G523-N698 WeakPolarHBondContact O-CB 3.46Å
524D97.5Very high98.4Very high37 Ų3715.1 Ų15.120%0.1988%0.078CC..SBendtrans58.352.2175.6-59.9-31.9000113.1E514 Y529 N698 K699E514-D524 VanDerWaalsContact CD-CA 3.43Å; E514-D524 VanDerWaalsContact OE1-CA 3.28Å; E514-D524 WeakPolarHBondContact OE1-CA 3.24Å; E514-D524 PolarHBondContact OE1-N 2.86Å; E514-D524 WeakPolarHBondContact OE2-CA 3.18Å; D524-Y529 HydrophobicContact CB-CD2 4.06Å; D524-Y529 HydrophobicContact CB-CE2 3.66Å; D524-Y529 WeakPolarHBondContact O-CE2 3.37Å; D524-N698 PolarHBondContact O-ND2 2.86Å; D524-K699 WeakPolarHBondContact OD2-CE 3.49Å; D524-K699 IonicContact OD2-NZ 2.73Å; D524-K699 PolarHBondContact OD2-NZ 3.13Å
525I98.3Very high98.4Very high5 Ų513.6 Ų13.63%0.0267%0.071CC..  trans-106.4-13.2-176.568.3164.8000114.6W231 C234 E514 N517 S519 F522 N698W231-I525 VanDerWaalsContact CB-O 3.29Å; W231-I525 WeakPolarHBondContact CB-O 3.5Å; W231-I525 HydrophobicContact CE3-CB 4.24Å; W231-I525 HydrophobicContact CZ3-CB 4.4Å; W231-I525 HydrophobicContact CZ3-CG2 4.42Å; C234-I525 VanDerWaalsContact CB-O 3.31Å; C234-I525 WeakPolarHBondContact CB-O 3.21Å; E514-I525 PolarHBondContact OE1-N 2.98Å; E514-I525 PolarHBondContact OE2-N 3Å; N517-I525 HydrophobicContact CB-CG1 4.41Å; N517-I525 WeakPolarHBondContact OD1-CD1 3.33Å; S519-I525 WeakPolarHBondContact OG-CD1 3.47Å; F522-I525 HydrophobicContact CB-CG2 3.61Å; I525-N698 HydrophobicContact CG2-CB 3.95Å
526M98.6Very high98.4Very high12 Ų129.9 Ų9.96%0.0595%0.052CC..SBendtrans-78.9-29-163.4-67-58.4-6700113.4L230 W231 L513 E514 L516 N517L230-M526 CarbonylContact C-O 3.54Å; L230-M526 WeakPolarHBondContact CA-O 3.28Å; L230-M526 WeakPolarHBondContact CB-O 3.49Å; L230-M526 HydrophobicContact CD1-CE 4.46Å; L230-M526 HydrophobicContact CD2-CE 4.06Å; L230-M526 WeakPolarHBondContact CD2-O 3.38Å; W231-M526 PolarHBondContact N-O 2.8Å; L513-M526 HydrophobicContact CB-CB 4.2Å; L513-M526 WeakPolarHBondContact O-CG 3.4Å; E514-M526 WeakPolarHBondContact OE2-CB 3.15Å; E514-M526 PolarHBondContact OE2-N 3.4Å; L516-M526 HydrophobicContact CB-CE 4.04Å; N517-M526 HydrophobicContact CB-CG 3.87Å; N517-M526 HydrophobicContact CB-SD 4.27Å
527I98.6Very high98.4Very high1 Ų18 Ų81%0.0054%0.042CC..SBendtrans-132.8159179.861.1176.4000110.6K507 K511 L513 Y529K507-I527 HydrophobicContact CD-CD1 3.98Å; K507-I527 HydrophobicContact CG-CD1 3.97Å; K511-I527 HydrophobicContact CG-CD1 4.34Å; L513-I527 HydrophobicContact CB-CG2 4.11Å; L513-I527 HydrophobicContact CD1-CG2 3.75Å; L513-I527 HydrophobicContact CG-CG2 4.49Å; I527-Y529 VanDerWaalsContact C-N 3.35Å; I527-Y529 HydrophobicContact CD1-CD1 4.06Å; I527-Y529 HydrophobicContact CD1-CE1 3.75Å; I527-Y529 HydrophobicContact CG1-CD1 4.02Å; I527-Y529 HydrophobicContact CG1-CD2 3.93Å; I527-Y529 HydrophobicContact CG1-CE1 3.74Å; I527-Y529 HydrophobicContact CG1-CE2 3.63Å; I527-Y529 HydrophobicContact CG1-CG 4.1Å; I527-Y529 WeakPolarHBondContact O-CD2 3.36Å; I527-Y529 WeakPolarHBondContact O-CE2 3.42Å; I527-Y529 PolarHBondContact O-N 3.29Å
528D98.7Very high98.5Very high3 Ų37.9 Ų7.92%0.0164%0.041CC..  trans-74.990.8171.4-158.2-8.6000109A502 T503 Y504 E505 K507A502-D528 HydrophobicContact CB-CB 4.14Å; A502-D528 WeakPolarHBondContact CB-OD1 3.44Å; T503-D528 PolarHBondContact N-OD1 3.45Å; T503-D528 VanDerWaalsContact OG1-CG 3.23Å; T503-D528 PolarHBondContact OG1-OD1 3.38Å; T503-D528 PolarHBondContact OG1-OD2 3.1Å; Y504-D528 PolarHBondContact N-OD2 2.84Å; Y504-D528 VanDerWaalsContact N-OD2 3.14Å; E505-D528 PolarHBondContact N-OD2 2.64Å; K507-D528 VanDerWaalsContact CA-O 3.31Å; K507-D528 WeakPolarHBondContact CA-O 3.47Å; K507-D528 VanDerWaalsContact CB-O 3.28Å; K507-D528 WeakPolarHBondContact CB-O 3.49Å
529Y98.8Very high98.5Very high28 Ų287.3 Ų7.311%0.114%0.037CC..  trans-64.8155.4-179.6-67.3-89.7000111A502 K511 E514 D524 I527 Y531A502-Y529 WeakPolarHBondContact CA-O 3.24Å; A502-Y529 WeakPolarHBondContact CB-O 3.26Å; K511-Y529 HydrophobicContact CG-CE1 4.47Å; E514-Y529 WeakPolarHBondContact CB-OH 3.45Å; E514-Y529 WeakPolarHBondContact CG-OH 3.41Å; E514-Y529 PolarHBondContact OE2-OH 2.71Å; D524-Y529 HydrophobicContact CB-CD2 4.06Å; D524-Y529 HydrophobicContact CB-CE2 3.66Å; D524-Y529 WeakPolarHBondContact O-CE2 3.37Å; I527-Y529 VanDerWaalsContact C-N 3.35Å; I527-Y529 HydrophobicContact CD1-CD1 4.06Å; I527-Y529 HydrophobicContact CD1-CE1 3.75Å; I527-Y529 HydrophobicContact CG1-CD1 4.02Å; I527-Y529 HydrophobicContact CG1-CD2 3.93Å; I527-Y529 HydrophobicContact CG1-CE1 3.74Å; I527-Y529 HydrophobicContact CG1-CE2 3.63Å; I527-Y529 HydrophobicContact CG1-CG 4.1Å; I527-Y529 WeakPolarHBondContact O-CD2 3.36Å; I527-Y529 WeakPolarHBondContact O-CE2 3.42Å; I527-Y529 PolarHBondContact O-N 3.29Å; Y529-Y531 WeakPolarHBondContact O-CD2 3.24Å; Y529-Y531 WeakPolarHBondContact O-CE2 3.43Å
530T98.8Very high98.6Very high19 Ų198.6 Ų8.612%0.1174%0.043CC..  trans-89.3132.8172.344.60000109.7N496 D498 F501 A502 K507 F567N496-T530 HydrophobicContact CB-CG2 3.92Å; D498-T530 PolarHBondContact OD2-OG1 3.08Å; D498-T530 VanDerWaalsContact OD2-OG1 3.06Å; F501-T530 CarbonylContact O-C 3.15Å; F501-T530 VanDerWaalsContact O-CA 3.27Å; F501-T530 WeakPolarHBondContact O-CA 3.42Å; A502-T530 HydrophobicContact CB-CG2 4.39Å; K507-T530 HydrophobicContact CB-CG2 4.43Å; K507-T530 PolarHBondContact NZ-OG1 2.99Å; T530-F567 WeakPolarHBondContact O-CZ 3.34Å; T530-F567 WeakPolarHBondContact OG1-CE2 3.19Å
531Y98.9Very high98.6Very high19 Ų198.4 Ų8.48%0.0754%0.042CC..BIsolated β-bridgetrans-123.7150.5-170.1-64-77000112.1F501 T503 Y529 E533 T535 S581 W582F501-Y531 PolarHBondContact O-N 2.9Å; T503-Y531 HydrophobicContact CG2-CD2 4.09Å; T503-Y531 HydrophobicContact CG2-CE2 3.99Å; Y529-Y531 WeakPolarHBondContact O-CD2 3.24Å; Y529-Y531 WeakPolarHBondContact O-CE2 3.43Å; Y531-E533 VanDerWaalsContact C-N 3.26Å; Y531-E533 WeakPolarHBondContact CB-OE2 3.17Å; Y531-E533 PolarHBondContact O-N 3.45Å; Y531-T535 VanDerWaalsContact O-CB 3.3Å; Y531-T535 WeakPolarHBondContact O-CB 3.41Å; Y531-T535 PolarHBondContact O-N 2.72Å; Y531-T535 VanDerWaalsContact O-N 3.09Å; Y531-T535 PolarHBondContact O-OG1 2.88Å; Y531-S581 WeakPolarHBondContact CD1-OG 3.43Å; Y531-S581 VanDerWaalsContact CE1-CB 3.47Å; Y531-S581 WeakPolarHBondContact CE1-OG 2.99Å; Y531-W582 AromaticContact CD1-NE1 3.97Å; Y531-W582 HydrophobicContact CD2-CZ2 4.17Å; Y531-W582 AromaticContact CD2-NE1 3.66Å; Y531-W582 HydrophobicContact CE1-CZ2 4.48Å; Y531-W582 AromaticContact CE2-CZ2 3.6Å; Y531-W582 HydrophobicContact CE2-CZ2 3.6Å; Y531-W582 AromaticContact CE2-NE1 3.95Å; Y531-W582 AromaticContact CG-NE1 3.66Å; Y531-W582 AromaticContact CZ-CZ2 3.76Å
532V98.9Very high98.7Very high7 Ų78.2 Ų8.24%0.0424%0.041CC..Hα-helixtrans-66.5-3417964.70000110.9T535 S536 C568 V571 W578V532-T535 PolarHBondContact O-N 2.95Å; V532-S536 WeakPolarHBondContact O-CB 3.35Å; V532-S536 PolarHBondContact O-N 3.11Å; V532-C568 HydrophobicContact CG2-CB 4.48Å; V532-V571 HydrophobicContact CB-CG2 4.34Å; V532-W578 HydrophobicContact CG1-CB 4.07Å; V532-W578 HydrophobicContact CG1-CG 4.35Å; V532-W578 HydrophobicContact CG2-CG 4.12Å
533E98.9Very high98.7Very high3 Ų311.8 Ų11.81%0.0146%0.055CC..Hα-helixtrans-69.1-51.5-177.5-49.4100.2116.400110.8Y531 T535 S536 A537 G580 S581 Y588 F592Y531-E533 VanDerWaalsContact C-N 3.26Å; Y531-E533 WeakPolarHBondContact CB-OE2 3.17Å; Y531-E533 PolarHBondContact O-N 3.45Å; E533-T535 VanDerWaalsContact C-N 3.3Å; E533-T535 PolarHBondContact O-N 3.08Å; E533-S536 PolarHBondContact O-N 3.32Å; E533-A537 WeakPolarHBondContact O-CB 3.36Å; E533-A537 PolarHBondContact O-N 2.96Å; E533-G580 WeakPolarHBondContact OE1-CA 3.26Å; E533-S581 PolarHBondContact OE1-N 3.12Å; E533-Y588 HydrophobicContact CB-CE1 4.33Å; E533-Y588 HydrophobicContact CG-CD1 4.01Å; E533-Y588 HydrophobicContact CG-CE1 3.62Å; E533-F592 HydrophobicContact CB-CB 4.36Å; E533-F592 HydrophobicContact CB-CD1 4.18Å; E533-F592 HydrophobicContact CB-CD2 3.81Å; E533-F592 HydrophobicContact CB-CE1 4.42Å; E533-F592 HydrophobicContact CB-CE2 4.11Å; E533-F592 HydrophobicContact CB-CG 3.85Å; E533-F592 HydrophobicContact CB-CZ 4.39Å; E533-F592 HydrophobicContact CG-CB 4.18Å; E533-F592 HydrophobicContact CG-CD2 3.64Å; E533-F592 HydrophobicContact CG-CE2 4.21Å; E533-F592 HydrophobicContact CG-CG 3.95Å
534C98.9Very high98.7Very high0 Ų012.9 Ų12.90%06%0.058CC..Hα-helixtrans-62.1-39.2176.5-48.80000111.8D456 F501 A502 A538D456-C534 PolarHBondContact OD2-SG 2.84Å; F501-C534 HydrophobicContact CB-CB 4.13Å; A502-C534 WeakPolarHBondContact O-CB 3.36Å; C534-A538 WeakPolarHBondContact O-CB 3.39Å; C534-A538 PolarHBondContact O-N 3.38Å; C534-A538 VanDerWaalsContact O-N 3.09Å
535T98.9Very high98.8Very high0 Ų011.1 Ų11.10%05%0.049CC..Hα-helixtrans-66.8-47.3178.3-53.70000111.3G500 F501 Y531 V532 E533 A538 M539 F567G500-T535 WeakPolarHBondContact CA-OG1 3.45Å; F501-T535 HydrophobicContact CD2-CG2 4.31Å; F501-T535 PolarHBondContact N-OG1 3.02Å; Y531-T535 VanDerWaalsContact O-CB 3.3Å; Y531-T535 WeakPolarHBondContact O-CB 3.41Å; Y531-T535 PolarHBondContact O-N 2.72Å; Y531-T535 VanDerWaalsContact O-N 3.09Å; Y531-T535 PolarHBondContact O-OG1 2.88Å; V532-T535 PolarHBondContact O-N 2.95Å; E533-T535 VanDerWaalsContact C-N 3.3Å; E533-T535 PolarHBondContact O-N 3.08Å; T535-A538 PolarHBondContact O-N 3.33Å; T535-M539 HydrophobicContact CG2-CG 4.47Å; T535-M539 HydrophobicContact CG2-SD 3.97Å; T535-M539 WeakPolarHBondContact O-CB 3.39Å; T535-M539 WeakPolarHBondContact O-CG 3.44Å; T535-M539 PolarHBondContact O-N 3.5Å; T535-F567 HydrophobicContact CG2-CD1 3.84Å; T535-F567 WeakPolarHBondContact OG1-CD1 3.47Å; T535-F567 WeakPolarHBondContact OG1-CE1 3.41Å
536S98.9Very high98.8Very high0 Ų011.1 Ų11.10%05%0.049CC..Hα-helixtrans-62.5-45.9178.6178.50000111.9V532 E533 A538 M539 Q540 F592 A596V532-S536 WeakPolarHBondContact O-CB 3.35Å; V532-S536 PolarHBondContact O-N 3.11Å; E533-S536 PolarHBondContact O-N 3.32Å; S536-A538 PolarHBondContact O-N 2.89Å; S536-M539 WeakPolarHBondContact O-CB 3.42Å; S536-M539 PolarHBondContact O-N 3.21Å; S536-Q540 VanDerWaalsContact O-CG 3.29Å; S536-Q540 WeakPolarHBondContact O-CG 3.46Å; S536-Q540 PolarHBondContact O-N 3.43Å; S536-Q540 PolarHBondContact O-NE2 3.27Å; S536-Q540 PolarHBondContact OG-NE2 3.16Å; S536-F592 WeakPolarHBondContact CB-O 3.12Å; S536-F592 PolarHBondContact OG-O 3.27Å; S536-A596 PolarHBondContact OG-N 3.04Å
537A98.9Very high98.7Very high0 Ų016.1 Ų16.10%07%0.072CC..Hα-helixtrans-57.7-50.4176.400000111.4D456 A459 E460 E533 M539 Q540 A541 F592D456-A537 HydrophobicContact CB-CB 3.97Å; A459-A537 HydrophobicContact CB-CB 4.14Å; A459-A537 WeakPolarHBondContact CB-O 3.38Å; E460-A537 HydrophobicContact CG-CB 4.48Å; E460-A537 WeakPolarHBondContact OE1-CB 3.47Å; E533-A537 WeakPolarHBondContact O-CB 3.36Å; E533-A537 PolarHBondContact O-N 2.96Å; A537-M539 VanDerWaalsContact C-N 3.33Å; A537-M539 PolarHBondContact O-N 3.49Å; A537-Q540 PolarHBondContact O-N 3.44Å; A537-A541 PolarHBondContact O-N 3.13Å; A537-F592 HydrophobicContact CB-CE1 4.41Å
538A98.9Very high98.6Very high0 Ų019.4 Ų19.40%09%0.092CC..Hα-helixtrans-59.5-42.2176.900000112.1F501 C534 T535 S536 L542F501-A538 HydrophobicContact CD1-CB 3.95Å; F501-A538 HydrophobicContact CD2-CB 3.95Å; F501-A538 HydrophobicContact CE1-CB 3.98Å; F501-A538 HydrophobicContact CE2-CB 4.01Å; F501-A538 HydrophobicContact CG-CB 3.92Å; F501-A538 HydrophobicContact CZ-CB 4.02Å; C534-A538 WeakPolarHBondContact O-CB 3.39Å; C534-A538 PolarHBondContact O-N 3.38Å; C534-A538 VanDerWaalsContact O-N 3.09Å; T535-A538 PolarHBondContact O-N 3.33Å; S536-A538 PolarHBondContact O-N 2.89Å; A538-L542 VanDerWaalsContact O-CB 3.25Å; A538-L542 WeakPolarHBondContact O-CB 3.43Å; A538-L542 WeakPolarHBondContact O-CG 3.41Å; A538-L542 PolarHBondContact O-N 2.87Å
539M98.9Very high98.5Very high1 Ų120.8 Ų20.81%0.00510%0.098CC..Hα-helixtrans-61-48176.2-74.217063.700112.1T535 S536 A537 A541 L542 R543 L561 L565 A596 M600T535-M539 HydrophobicContact CG2-CG 4.47Å; T535-M539 HydrophobicContact CG2-SD 3.97Å; T535-M539 WeakPolarHBondContact O-CB 3.39Å; T535-M539 WeakPolarHBondContact O-CG 3.44Å; T535-M539 PolarHBondContact O-N 3.5Å; S536-M539 WeakPolarHBondContact O-CB 3.42Å; S536-M539 PolarHBondContact O-N 3.21Å; A537-M539 VanDerWaalsContact C-N 3.33Å; A537-M539 PolarHBondContact O-N 3.49Å; M539-A541 PolarHBondContact O-N 3.38Å; M539-L542 PolarHBondContact O-N 2.95Å; M539-R543 WeakPolarHBondContact O-CB 3.42Å; M539-R543 PolarHBondContact O-N 3.16Å; M539-L561 HydrophobicContact CB-CD2 3.91Å; M539-L561 HydrophobicContact CG-CD2 4.13Å; M539-L561 VanDerWaalsContact O-CD2 3.22Å; M539-L561 WeakPolarHBondContact O-CD2 3.38Å; M539-L565 HydrophobicContact CE-CB 3.85Å; M539-L565 HydrophobicContact CE-CD1 4.37Å; M539-A596 HydrophobicContact CE-CB 4.02Å; M539-A596 HydrophobicContact SD-CB 4.12Å; M539-M600 HydrophobicContact CE-CG 3.68Å; M539-M600 HydrophobicContact CE-SD 4.25Å
540Q98.9Very high98.4Very high26 Ų2622.7 Ų22.712%0.12111%0.114CC..Hα-helixtrans-60.6-47.2180-69.216952.900111.6K463 S536 A537 R543 H544 C599K463-Q540 HydrophobicContact CD-CB 4.16Å; S536-Q540 VanDerWaalsContact O-CG 3.29Å; S536-Q540 WeakPolarHBondContact O-CG 3.46Å; S536-Q540 PolarHBondContact O-N 3.43Å; S536-Q540 PolarHBondContact O-NE2 3.27Å; S536-Q540 PolarHBondContact OG-NE2 3.16Å; A537-Q540 PolarHBondContact O-N 3.44Å; Q540-R543 PolarHBondContact O-N 3.41Å; Q540-H544 WeakPolarHBondContact O-CB 3.38Å; Q540-H544 PolarHBondContact O-N 3.43Å; Q540-C599 HydrophobicContact CG-CB 4.18Å
541A98.9Very high98.3Very high0 Ų029.1 Ų29.10%015%0.148CC..Hα-helixtrans-64.4-47179.300000112A459 K463 A537 M539 R543 H544 F545A459-A541 HydrophobicContact CB-CB 3.72Å; A459-A541 VanDerWaalsContact O-CB 3.25Å; A459-A541 WeakPolarHBondContact O-CB 3.42Å; K463-A541 HydrophobicContact CB-CB 4.25Å; A537-A541 PolarHBondContact O-N 3.13Å; M539-A541 PolarHBondContact O-N 3.38Å; A541-R543 VanDerWaalsContact C-N 3.33Å; A541-R543 PolarHBondContact O-N 3.35Å; A541-H544 PolarHBondContact O-N 3.24Å; A541-F545 VanDerWaalsContact O-CB 3.31Å; A541-F545 WeakPolarHBondContact O-CB 3.34Å; A541-F545 PolarHBondContact O-N 2.92Å
542L98.9Very high98.2Very high0 Ų030.2 Ų30.20%015%0.154CC..Hα-helixtrans-66.3-34.7178.3-71.6175.9000112.3V488 L491 L492 A538 M539 L546 I557 T560 L561V488-L542 HydrophobicContact CB-CD2 4.49Å; V488-L542 HydrophobicContact CG1-CD2 3.92Å; V488-L542 HydrophobicContact CG2-CD2 4.25Å; L491-L542 HydrophobicContact CB-CD2 4.46Å; L491-L542 HydrophobicContact CD1-CD2 4.1Å; L491-L542 HydrophobicContact CD1-CG 4.14Å; L492-L542 HydrophobicContact CD2-CD1 4.36Å; A538-L542 VanDerWaalsContact O-CB 3.25Å; A538-L542 WeakPolarHBondContact O-CB 3.43Å; A538-L542 WeakPolarHBondContact O-CG 3.41Å; A538-L542 PolarHBondContact O-N 2.87Å; M539-L542 PolarHBondContact O-N 2.95Å; L542-L546 WeakPolarHBondContact O-CB 3.17Å; L542-L546 PolarHBondContact O-N 2.89Å; L542-I557 HydrophobicContact CB-CG2 4Å; L542-T560 HydrophobicContact CD1-CG2 3.86Å; L542-L561 HydrophobicContact CB-CD2 4.23Å
543R98.7Very high98.2Very high82 Ų8234.3 Ų34.331%0.30917%0.168SC..Hα-helixtrans-65.2-46.7175.9179.159.3175.9150.80.2111.2M539 Q540 A541 L546 Q547 L561M539-R543 WeakPolarHBondContact O-CB 3.42Å; M539-R543 PolarHBondContact O-N 3.16Å; Q540-R543 PolarHBondContact O-N 3.41Å; A541-R543 VanDerWaalsContact C-N 3.33Å; A541-R543 PolarHBondContact O-N 3.35Å; R543-L546 PolarHBondContact O-N 2.93Å; R543-Q547 WeakPolarHBondContact O-CG 3.43Å; R543-Q547 PolarHBondContact O-N 2.71Å; R543-L561 HydrophobicContact CB-CD1 4.27Å; R543-L561 HydrophobicContact CB-CD2 4.15Å
544H98.6Very high98.2Very high27 Ų2735.3 Ų35.313%0.12518%0.177CC..Hα-helixtrans-65.1-44.7176.1-176.465.5000111.2M466 E470 Q540 A541 L546 Q547 V548M466-H544 VanDerWaalsContact CE-CD2 3.47Å; M466-H544 WeakPolarHBondContact CE-CD2 3.46Å; E470-H544 IonicContact OE2-CE1 3.5Å; E470-H544 PolarHBondContact OE2-CE1 3.03Å; E470-H544 VanDerWaalsContact OE2-CE1 3.31Å; E470-H544 IonicContact OE2-NE2 3.4Å; Q540-H544 WeakPolarHBondContact O-CB 3.38Å; Q540-H544 PolarHBondContact O-N 3.43Å; A541-H544 PolarHBondContact O-N 3.24Å; H544-L546 VanDerWaalsContact C-N 3.32Å; H544-L546 PolarHBondContact O-N 3.45Å; H544-Q547 WeakPolarHBondContact O-CB 3.41Å; H544-Q547 PolarHBondContact O-N 3.23Å; H544-V548 PolarHBondContact O-N 2.66Å
545F98.8Very high98.1Very high0 Ų039.1 Ų39.10%021%0.209CC..Hα-helixtrans-54.1-45.9173.3178.4-89.2000112.6M466 L484 Y485 V488 A541 Q547 V548 H549 H552 I557M466-F545 VanDerWaalsContact CE-CA 3.49Å; M466-F545 HydrophobicContact CE-CB 4.26Å; M466-F545 HydrophobicContact CE-CD2 4.42Å; M466-F545 HydrophobicContact SD-CB 4Å; M466-F545 HydrophobicContact SD-CD2 4.07Å; L484-F545 HydrophobicContact CB-CE2 4.27Å; Y485-F545 AromaticContact CD1-CE2 3.68Å; Y485-F545 HydrophobicContact CD1-CE2 3.68Å; Y485-F545 AromaticContact CD1-CZ 3.42Å; Y485-F545 HydrophobicContact CD1-CZ 3.42Å; Y485-F545 VanDerWaalsContact CD1-CZ 3.42Å; Y485-F545 AromaticContact CE1-CE2 3.87Å; Y485-F545 HydrophobicContact CE1-CE2 3.87Å; Y485-F545 AromaticContact CE1-CZ 3.55Å; Y485-F545 HydrophobicContact CE1-CZ 3.55Å; V488-F545 HydrophobicContact CG1-CE1 4.37Å; V488-F545 HydrophobicContact CG2-CB 4.41Å; V488-F545 HydrophobicContact CG2-CD1 3.8Å; V488-F545 HydrophobicContact CG2-CD2 3.6Å; V488-F545 HydrophobicContact CG2-CE1 3.92Å; V488-F545 HydrophobicContact CG2-CE2 3.72Å; V488-F545 HydrophobicContact CG2-CG 3.64Å; V488-F545 HydrophobicContact CG2-CZ 3.88Å; A541-F545 VanDerWaalsContact O-CB 3.31Å; A541-F545 WeakPolarHBondContact O-CB 3.34Å; A541-F545 PolarHBondContact O-N 2.92Å; F545-Q547 VanDerWaalsContact C-N 3.25Å; F545-Q547 PolarHBondContact O-N 2.8Å; F545-V548 PolarHBondContact O-N 2.94Å; F545-H549 HydrophobicContact CD1-CB 4.42Å; F545-H549 AromaticContact CD2-CD2 3.77Å; F545-H549 HydrophobicContact CE1-CB 3.87Å; F545-H549 HydrophobicContact CE2-CB 4.05Å; F545-H549 AromaticContact CE2-CD2 3.43Å; F545-H549 VanDerWaalsContact CE2-CD2 3.43Å; F545-H549 WeakPolarHBondContact CE2-CD2 3.17Å; F545-H549 AromaticContact CE2-CG 3.9Å; F545-H549 HydrophobicContact CZ-CB 3.66Å; F545-H549 AromaticContact CZ-CD2 3.97Å; F545-H549 AromaticContact CZ-CG 3.96Å; F545-H549 PolarHBondContact O-N 3.44Å; F545-H552 HydrophobicContact CE1-CB 4.07Å; F545-H552 AromaticContact CE1-CD2 3.87Å; F545-H552 HydrophobicContact CZ-CB 4.1Å; F545-H552 AromaticContact CZ-CD2 3.79Å; F545-I557 HydrophobicContact CD1-CD1 3.78Å; F545-I557 HydrophobicContact CE1-CD1 3.9Å
546L98.3Very high98.1Very high5 Ų541.8 Ų41.83%0.02622%0.221CC..Hα-helixtrans-65.3-26.7179.1-174.364.5000113.2L542 R543 H544 P550 A554 I557 R558 L561L542-L546 WeakPolarHBondContact O-CB 3.17Å; L542-L546 PolarHBondContact O-N 2.89Å; R543-L546 PolarHBondContact O-N 2.93Å; H544-L546 VanDerWaalsContact C-N 3.32Å; H544-L546 PolarHBondContact O-N 3.45Å; L546-P550 VanDerWaalsContact O-CA 3.28Å; L546-P550 WeakPolarHBondContact O-CA 3.42Å; L546-A554 HydrophobicContact CD1-CB 3.83Å; L546-I557 HydrophobicContact CB-CG2 4.14Å; L546-I557 HydrophobicContact CD2-CG2 4.1Å; L546-R558 HydrophobicContact CD2-CG 3.75Å; L546-L561 HydrophobicContact CD2-CD1 4.46Å
547Q96.9Very high98.1Very high118 Ų11841.8 Ų41.855%0.55122%0.221SC*.Hα-helixtrans-71.2-39.2174.9-70.3169.1-24.100111.4R543 H544 F545R543-Q547 WeakPolarHBondContact O-CG 3.43Å; R543-Q547 PolarHBondContact O-N 2.71Å; H544-Q547 WeakPolarHBondContact O-CB 3.41Å; H544-Q547 PolarHBondContact O-N 3.23Å; F545-Q547 VanDerWaalsContact C-N 3.25Å; F545-Q547 PolarHBondContact O-N 2.8Å
548V95.9Very high98.1Very high70 Ų7048.4 Ų48.442%0.42425%0.246SC..Hα-helixtrans-83.4-34.3-178.6-178.80000112.1M466 H544 F545 P550M466-V548 HydrophobicContact CE-CB 3.62Å; M466-V548 HydrophobicContact CE-CG1 4.16Å; M466-V548 HydrophobicContact CE-CG2 3.51Å; H544-V548 PolarHBondContact O-N 2.66Å; F545-V548 PolarHBondContact O-N 2.94Å; V548-P550 WeakPolarHBondContact O-CD 3.33Å
549H97.1Very high98.1Very high32 Ų3250.9 Ų50.915%0.14826%0.263CS..  trans-124.369.9-178.4-63.8-75.8000111.5Y485 F545 D551 H552Y485-H549 HydrophobicContact CE1-CB 4.39Å; Y485-H549 AromaticContact CE1-CG 3.96Å; Y485-H549 AromaticContact CE1-ND1 3.86Å; Y485-H549 PolarHBondContact OH-ND1 2.78Å; F545-H549 HydrophobicContact CD1-CB 4.42Å; F545-H549 AromaticContact CD2-CD2 3.77Å; F545-H549 HydrophobicContact CE1-CB 3.87Å; F545-H549 HydrophobicContact CE2-CB 4.05Å; F545-H549 AromaticContact CE2-CD2 3.43Å; F545-H549 VanDerWaalsContact CE2-CD2 3.43Å; F545-H549 WeakPolarHBondContact CE2-CD2 3.17Å; F545-H549 AromaticContact CE2-CG 3.9Å; F545-H549 HydrophobicContact CZ-CB 3.66Å; F545-H549 AromaticContact CZ-CD2 3.97Å; F545-H549 AromaticContact CZ-CG 3.96Å; F545-H549 PolarHBondContact O-N 3.44Å; H549-D551 PolarHBondContact O-N 3.3Å; H549-D551 VanDerWaalsContact O-N 3.15Å; H549-H552 HydrophobicContact CB-CB 4.37Å; H549-H552 PolarHBondContact O-N 3.28Å
550P96.9Very high98.1Very high67 Ų6750.9 Ų50.944%0.43526%0.263SS..THydrogen-bonded Turntrans-65.8-20.4-169.126.1-36.1000115.1L546 V548 A554L546-P550 VanDerWaalsContact O-CA 3.28Å; L546-P550 WeakPolarHBondContact O-CA 3.42Å; V548-P550 WeakPolarHBondContact O-CD 3.33Å; P550-A554 VanDerWaalsContact O-CB 3.22Å; P550-A554 WeakPolarHBondContact O-CB 3.43Å
551D96.4Very high98.1Very high155 Ų15549.9 Ų49.983%0.82926%0.259SS*.THydrogen-bonded Turntrans-95.6-15.9-176.2-58.6-45.6000113.5H549 R553H549-D551 PolarHBondContact O-N 3.3Å; H549-D551 VanDerWaalsContact O-N 3.15Å; D551-R553 PolarHBondContact O-N 3.4Å
552H97.4Very high98.1Very high42 Ų4253.6 Ų53.619%0.19428%0.282CS..SBendtrans-84108.8-174-171.483.8000111.7Y485 F545 H549 A554 I557Y485-H552 AromaticContact CD1-CD2 3.95Å; Y485-H552 AromaticContact CD1-CG 3.95Å; Y485-H552 AromaticContact CD2-CE1 3.52Å; Y485-H552 AromaticContact CD2-ND1 3.64Å; Y485-H552 HydrophobicContact CE1-CB 4.21Å; Y485-H552 AromaticContact CE1-CG 3.96Å; Y485-H552 AromaticContact CE2-ND1 3.69Å; Y485-H552 AromaticContact CG-CE1 3.51Å; Y485-H552 AromaticContact CG-ND1 3.81Å; Y485-H552 AromaticContact CG-NE2 3.73Å; Y485-H552 AromaticContact CZ-ND1 3.92Å; F545-H552 HydrophobicContact CE1-CB 4.07Å; F545-H552 AromaticContact CE1-CD2 3.87Å; F545-H552 HydrophobicContact CZ-CB 4.1Å; F545-H552 AromaticContact CZ-CD2 3.79Å; H549-H552 HydrophobicContact CB-CB 4.37Å; H549-H552 PolarHBondContact O-N 3.28Å; H552-A554 PolarHBondContact O-N 2.72Å; H552-I557 WeakPolarHBondContact O-CD1 3.33Å
553R97.9Very high98.1Very high93 Ų9356.6 Ų56.635%0.35130%0.298SS..SBendtrans50.531178.9-61-176.273.9173.13.2113.9N489 L492 D551 A555 E556 I557N489-R553 PolarHBondContact OD1-NH1 3.13Å; L492-R553 HydrophobicContact CD1-CB 4.32Å; L492-R553 VanDerWaalsContact CD1-CZ 3.43Å; D551-R553 PolarHBondContact O-N 3.4Å; R553-A555 VanDerWaalsContact C-N 3.33Å; R553-A555 PolarHBondContact O-N 3.07Å; R553-E556 IonicContact CZ-OE1 2.78Å; R553-E556 IonicContact CZ-OE2 3.11Å; R553-E556 IonicContact NE-OE2 2.64Å; R553-E556 PolarHBondContact NE-OE2 3.48Å; R553-E556 IonicContact NH2-OE1 3.12Å; R553-E556 PolarHBondContact NH2-OE1 2.8Å; R553-E556 IonicContact NH2-OE2 3.07Å; R553-E556 PolarHBondContact NH2-OE2 3.31Å; R553-E556 PolarHBondContact O-N 3.29Å; R553-E556 VanDerWaalsContact O-N 3.1Å; R553-I557 PolarHBondContact O-N 2.86Å
554A98.2Very high98.1Very high23 Ų2352.7 Ų52.719%0.1928%0.283CS..Hα-helixtrans-54-43-169.400000114.5L546 P550 H552 E556 I557 R558L546-A554 HydrophobicContact CD1-CB 3.83Å; P550-A554 VanDerWaalsContact O-CB 3.22Å; P550-A554 WeakPolarHBondContact O-CB 3.43Å; H552-A554 PolarHBondContact O-N 2.72Å; A554-E556 PolarHBondContact O-N 3.42Å; A554-I557 PolarHBondContact O-N 3.31Å; A554-R558 WeakPolarHBondContact O-CB 3.4Å; A554-R558 VanDerWaalsContact O-CG 3.26Å; A554-R558 WeakPolarHBondContact O-CG 3.28Å; A554-R558 PolarHBondContact O-N 3.42Å
555A98.4Very high98.1Very high81 Ų8152 Ų5267%0.66928%0.28SS*.Hα-helixtrans-62.9-43.6-179.100000112.1R553 R558 S559R553-A555 VanDerWaalsContact C-N 3.33Å; R553-A555 PolarHBondContact O-N 3.07Å; A555-R558 PolarHBondContact O-N 2.9Å; A555-S559 PolarHBondContact O-N 2.99Å
556E98.4Very high98.1Very high56 Ų5655.2 Ų55.226%0.26230%0.295SS..Hα-helixtrans-71.2-38.8-179.5-170.7179.2177.200112L492 R495 R553 A554 S559 T560L492-E556 HydrophobicContact CD1-CG 4.47Å; L492-E556 HydrophobicContact CD2-CG 4.26Å; R495-E556 IonicContact NH1-OE1 2.8Å; R553-E556 IonicContact CZ-OE1 2.78Å; R553-E556 IonicContact CZ-OE2 3.11Å; R553-E556 IonicContact NE-OE2 2.64Å; R553-E556 PolarHBondContact NE-OE2 3.48Å; R553-E556 IonicContact NH2-OE1 3.12Å; R553-E556 PolarHBondContact NH2-OE1 2.8Å; R553-E556 IonicContact NH2-OE2 3.07Å; R553-E556 PolarHBondContact NH2-OE2 3.31Å; R553-E556 PolarHBondContact O-N 3.29Å; R553-E556 VanDerWaalsContact O-N 3.1Å; A554-E556 PolarHBondContact O-N 3.42Å; E556-S559 PolarHBondContact O-N 3.24Å; E556-T560 WeakPolarHBondContact O-CB 3.21Å; E556-T560 PolarHBondContact O-N 3.2Å; E556-T560 PolarHBondContact O-OG1 2.83Å
557I98.8Very high98.1Very high0 Ų055.3 Ų55.30%030%0.295CS..Hα-helixtrans-61.7-47.1173.9-65.6173.5000110.1V488 L492 L542 F545 L546 H552 R553 A554 S559 T560 L561V488-I557 HydrophobicContact CG1-CD1 4.19Å; L492-I557 HydrophobicContact CD1-CG1 4.22Å; L492-I557 HydrophobicContact CD2-CG1 4.33Å; L542-I557 HydrophobicContact CB-CG2 4Å; F545-I557 HydrophobicContact CD1-CD1 3.78Å; F545-I557 HydrophobicContact CE1-CD1 3.9Å; L546-I557 HydrophobicContact CB-CG2 4.14Å; L546-I557 HydrophobicContact CD2-CG2 4.1Å; H552-I557 WeakPolarHBondContact O-CD1 3.33Å; R553-I557 PolarHBondContact O-N 2.86Å; A554-I557 PolarHBondContact O-N 3.31Å; I557-S559 VanDerWaalsContact C-N 3.34Å; I557-S559 PolarHBondContact O-N 3.37Å; I557-T560 WeakPolarHBondContact O-CB 3.49Å; I557-T560 PolarHBondContact O-N 3.41Å; I557-T560 VanDerWaalsContact O-N 3.12Å; I557-L561 HydrophobicContact CG2-CD1 4.07Å; I557-L561 HydrophobicContact CG2-CG 4.31Å; I557-L561 VanDerWaalsContact O-CG 3.31Å; I557-L561 WeakPolarHBondContact O-CG 3.25Å; I557-L561 PolarHBondContact O-N 3.17Å
558R98.8Very high98.2Very high139 Ų13949.7 Ų49.753%0.52527%0.269SS..Hα-helixtrans-60.4-41.3177.5-72175.1-165.8-92.62112.7L546 A554 A555 L561 T562L546-R558 HydrophobicContact CD2-CG 3.75Å; A554-R558 WeakPolarHBondContact O-CB 3.4Å; A554-R558 VanDerWaalsContact O-CG 3.26Å; A554-R558 WeakPolarHBondContact O-CG 3.28Å; A554-R558 PolarHBondContact O-N 3.42Å; A555-R558 PolarHBondContact O-N 2.9Å; R558-L561 PolarHBondContact O-N 3.41Å; R558-T562 PolarHBondContact O-N 3Å; R558-T562 VanDerWaalsContact O-N 3.09Å; R558-T562 PolarHBondContact O-OG1 3.3Å
559S98.7Very high98.4Very high51 Ų5150 Ų5036%0.35726%0.262SS..Hα-helixtrans-60.1-47.8172.9-177.20000110.7A555 E556 I557 L561 T562 D563A555-S559 PolarHBondContact O-N 2.99Å; E556-S559 PolarHBondContact O-N 3.24Å; I557-S559 VanDerWaalsContact C-N 3.34Å; I557-S559 PolarHBondContact O-N 3.37Å; S559-L561 VanDerWaalsContact C-N 3.32Å; S559-L561 PolarHBondContact O-N 3.07Å; S559-T562 PolarHBondContact O-N 3.05Å; S559-T562 VanDerWaalsContact O-N 3.13Å; S559-D563 WeakPolarHBondContact O-CB 3.37Å; S559-D563 PolarHBondContact O-N 3.49Å; S559-D563 PolarHBondContact OG-OD2 2.67Å
560T98.9Very high98.4Very high2 Ų255.1 Ų55.11%0.01228%0.281CS..Hα-helixtrans-59.7-41.7-180-56.50000112.1L492 R495 F501 L542 E556 I557 G564L492-T560 HydrophobicContact CD2-CG2 4.43Å; R495-T560 WeakPolarHBondContact CD-OG1 3.34Å; R495-T560 HydrophobicContact CG-CG2 4.14Å; R495-T560 PolarHBondContact NE-OG1 3.29Å; F501-T560 HydrophobicContact CE2-CG2 3.72Å; F501-T560 HydrophobicContact CZ-CG2 3.69Å; L542-T560 HydrophobicContact CD1-CG2 3.86Å; E556-T560 WeakPolarHBondContact O-CB 3.21Å; E556-T560 PolarHBondContact O-N 3.2Å; E556-T560 PolarHBondContact O-OG1 2.83Å; I557-T560 WeakPolarHBondContact O-CB 3.49Å; I557-T560 PolarHBondContact O-N 3.41Å; I557-T560 VanDerWaalsContact O-N 3.12Å; T560-G564 PolarHBondContact O-N 2.6Å
561L98.9Very high98.5Very high5 Ų555 Ų553%0.02628%0.278CS..Hα-helixtrans-64.2-40175.9-67.8174.1000112.4M539 L542 R543 L546 I557 R558 S559 L565 M600M539-L561 HydrophobicContact CB-CD2 3.91Å; M539-L561 HydrophobicContact CG-CD2 4.13Å; M539-L561 VanDerWaalsContact O-CD2 3.22Å; M539-L561 WeakPolarHBondContact O-CD2 3.38Å; L542-L561 HydrophobicContact CB-CD2 4.23Å; R543-L561 HydrophobicContact CB-CD1 4.27Å; R543-L561 HydrophobicContact CB-CD2 4.15Å; L546-L561 HydrophobicContact CD2-CD1 4.46Å; I557-L561 HydrophobicContact CG2-CD1 4.07Å; I557-L561 HydrophobicContact CG2-CG 4.31Å; I557-L561 VanDerWaalsContact O-CG 3.31Å; I557-L561 WeakPolarHBondContact O-CG 3.25Å; I557-L561 PolarHBondContact O-N 3.17Å; R558-L561 PolarHBondContact O-N 3.41Å; S559-L561 VanDerWaalsContact C-N 3.32Å; S559-L561 PolarHBondContact O-N 3.07Å; L561-L565 PolarHBondContact O-N 2.76Å; L561-M600 HydrophobicContact CB-CE 4.03Å; L561-M600 HydrophobicContact CB-SD 3.9Å
562T98.8Very high98.6Very high78 Ų7849 Ų4948%0.47925%0.245SC..Hα-helixtrans-68-48.6178.2-53.70000110.8R558 S559 G564 L565 E566R558-T562 PolarHBondContact O-N 3Å; R558-T562 VanDerWaalsContact O-N 3.09Å; R558-T562 PolarHBondContact O-OG1 3.3Å; S559-T562 PolarHBondContact O-N 3.05Å; S559-T562 VanDerWaalsContact O-N 3.13Å; T562-G564 VanDerWaalsContact C-N 3.29Å; T562-G564 PolarHBondContact O-N 3.02Å; T562-L565 PolarHBondContact O-N 3.32Å; T562-E566 PolarHBondContact O-N 2.64Å; T562-E566 VanDerWaalsContact O-N 3.09Å
563D98.9Very high98.7Very high63 Ų6350.2 Ų50.234%0.33725%0.248SC..Hα-helixtrans-61.6-39.4178.7-62.7-27.6000111.4R495 S559 E566 F567R495-D563 IonicContact NH2-OD2 3.93Å; R495-D563 PolarHBondContact NH2-OD2 2.62Å; S559-D563 WeakPolarHBondContact O-CB 3.37Å; S559-D563 PolarHBondContact O-N 3.49Å; S559-D563 PolarHBondContact OG-OD2 2.67Å; D563-E566 PolarHBondContact O-N 2.94Å; D563-F567 PolarHBondContact O-N 3.19Å
564G98.9Very high98.7Very high0 Ų052.1 Ų52.10%027%0.27CS..Hα-helixtrans-65.7-43.9176.900000113G499 T560 T562 E566 F567 C568G499-G564 WeakPolarHBondContact O-CA 3.17Å; T560-G564 PolarHBondContact O-N 2.6Å; T562-G564 VanDerWaalsContact C-N 3.29Å; T562-G564 PolarHBondContact O-N 3.02Å; G564-E566 VanDerWaalsContact C-N 3.32Å; G564-E566 PolarHBondContact O-N 2.82Å; G564-F567 WeakPolarHBondContact O-CB 3.34Å; G564-F567 PolarHBondContact O-N 2.97Å; G564-C568 PolarHBondContact O-N 2.79Å; G564-C568 PolarHBondContact O-SG 3.27Å; G564-C568 VanDerWaalsContact O-SG 3.34Å
565L98.9Very high98.7Very high11 Ų1154.7 Ų54.76%0.05828%0.281CS..Hα-helixtrans-62.1-42.1175.5-177.464.8000111.3M539 L561 T562 F567 C568 R569 F597 M600 H602M539-L565 HydrophobicContact CE-CB 3.85Å; M539-L565 HydrophobicContact CE-CD1 4.37Å; L561-L565 PolarHBondContact O-N 2.76Å; T562-L565 PolarHBondContact O-N 3.32Å; L565-F567 VanDerWaalsContact C-N 3.32Å; L565-F567 PolarHBondContact O-N 3.36Å; L565-C568 WeakPolarHBondContact O-CB 3.36Å; L565-C568 PolarHBondContact O-N 3.09Å; L565-R569 PolarHBondContact O-N 2.64Å; L565-F597 HydrophobicContact CD1-CD1 3.96Å; L565-F597 HydrophobicContact CD1-CD2 3.98Å; L565-F597 HydrophobicContact CD1-CE1 4.05Å; L565-F597 HydrophobicContact CD1-CE2 4.08Å; L565-F597 HydrophobicContact CD1-CG 3.93Å; L565-F597 HydrophobicContact CD1-CZ 4.11Å; L565-M600 HydrophobicContact CB-CG 4.36Å; L565-M600 HydrophobicContact CD1-CB 4.48Å; L565-M600 HydrophobicContact CD1-CG 4.27Å; L565-M600 HydrophobicContact CD2-CB 4.02Å; L565-M600 HydrophobicContact CD2-CE 4.35Å; L565-M600 HydrophobicContact CD2-CG 4.08Å; L565-M600 HydrophobicContact CG-CG 4.47Å; L565-H602 WeakPolarHBondContact CD2-NE2 3.35Å
566E98.8Very high98.7Very high69 Ų6950.9 Ų50.932%0.32225%0.249SC..Hα-helixtrans-67.6-31.9176.6-73.8-57122.100112.6T562 D563 G564 R569 R570T562-E566 PolarHBondContact O-N 2.64Å; T562-E566 VanDerWaalsContact O-N 3.09Å; D563-E566 PolarHBondContact O-N 2.94Å; G564-E566 VanDerWaalsContact C-N 3.32Å; G564-E566 PolarHBondContact O-N 2.82Å; E566-R569 IonicContact OE1-CZ 3.13Å; E566-R569 IonicContact OE1-NE 2.68Å; E566-R569 PolarHBondContact OE1-NE 3.07Å; E566-R569 IonicContact OE1-NH2 3.62Å; E566-R569 PolarHBondContact OE1-NH2 3.13Å; E566-R569 IonicContact OE2-NE 3.9Å; E566-R570 WeakPolarHBondContact O-CG 3.24Å; E566-R570 PolarHBondContact O-N 2.56Å; E566-R570 VanDerWaalsContact O-N 3.07Å; E566-R570 PolarHBondContact O-NH1 3.42Å
567F98.9Very high98.8Very high6 Ų648.2 Ų48.23%0.02624%0.236CC..Hα-helixtrans-60.6-53167.6171.9-93000111.1D498 T530 T535 D563 G564 L565 R569 R570 V571D498-F567 WeakPolarHBondContact O-CB 3.14Å; D498-F567 WeakPolarHBondContact O-CD2 3.39Å; T530-F567 WeakPolarHBondContact O-CZ 3.34Å; T530-F567 WeakPolarHBondContact OG1-CE2 3.19Å; T535-F567 HydrophobicContact CG2-CD1 3.84Å; T535-F567 WeakPolarHBondContact OG1-CD1 3.47Å; T535-F567 WeakPolarHBondContact OG1-CE1 3.41Å; D563-F567 PolarHBondContact O-N 3.19Å; G564-F567 WeakPolarHBondContact O-CB 3.34Å; G564-F567 PolarHBondContact O-N 2.97Å; L565-F567 VanDerWaalsContact C-N 3.32Å; L565-F567 PolarHBondContact O-N 3.36Å; F567-R569 VanDerWaalsContact C-N 3.27Å; F567-R569 PolarHBondContact O-N 2.88Å; F567-R570 PolarHBondContact O-N 3.37Å; F567-V571 HydrophobicContact CD1-CG2 4.28Å; F567-V571 HydrophobicContact CD2-CG1 4.19Å; F567-V571 HydrophobicContact CE1-CG1 4.25Å; F567-V571 HydrophobicContact CE1-CG2 3.88Å; F567-V571 HydrophobicContact CE2-CG1 3.7Å; F567-V571 HydrophobicContact CZ-CG1 3.73Å; F567-V571 HydrophobicContact CZ-CG2 4.16Å; F567-V571 WeakPolarHBondContact O-CG2 3.29Å; F567-V571 PolarHBondContact O-N 3.41Å
568C98.9Very high98.8Very high0 Ų048.3 Ų48.30%024%0.237CC..Hα-helixtrans-55.4-42.7178.8-66.60000111.5V532 G564 L565 V571 Q572 W578 F597V532-C568 HydrophobicContact CG2-CB 4.48Å; G564-C568 PolarHBondContact O-N 2.79Å; G564-C568 PolarHBondContact O-SG 3.27Å; G564-C568 VanDerWaalsContact O-SG 3.34Å; L565-C568 WeakPolarHBondContact O-CB 3.36Å; L565-C568 PolarHBondContact O-N 3.09Å; C568-V571 PolarHBondContact O-N 3.1Å; C568-Q572 PolarHBondContact O-N 3.2Å; C568-W578 PolarHBondContact O-NE1 3.14Å; C568-F597 HydrophobicContact CB-CE2 4.32Å
569R98.8Very high98.8Very high77 Ų7743 Ų4329%0.29122%0.218SC..Hα-helixtrans-58.3-47.6174.5-167.5-171.1-60.2-93.80112.1L565 E566 F567 V571 Q572 F597 E612L565-R569 PolarHBondContact O-N 2.64Å; E566-R569 IonicContact OE1-CZ 3.13Å; E566-R569 IonicContact OE1-NE 2.68Å; E566-R569 PolarHBondContact OE1-NE 3.07Å; E566-R569 IonicContact OE1-NH2 3.62Å; E566-R569 PolarHBondContact OE1-NH2 3.13Å; E566-R569 IonicContact OE2-NE 3.9Å; F567-R569 VanDerWaalsContact C-N 3.27Å; F567-R569 PolarHBondContact O-N 2.88Å; R569-V571 PolarHBondContact O-N 3.12Å; R569-Q572 PolarHBondContact O-N 2.78Å; R569-F597 HydrophobicContact CB-CZ 4.34Å; R569-E612 WeakPolarHBondContact CD-OE1 3.44Å; R569-E612 HydrophobicContact CG-CG 3.96Å; R569-E612 WeakPolarHBondContact CG-OE1 3.32Å; R569-E612 IonicContact CZ-OE1 2.69Å; R569-E612 IonicContact NE-OE1 2.8Å; R569-E612 IonicContact NH1-OE1 3.69Å; R569-E612 PolarHBondContact NH1-OE1 2.92Å; R569-E612 IonicContact NH1-OE2 3.74Å; R569-E612 PolarHBondContact NH1-OE2 3.4Å; R569-E612 VanDerWaalsContact NH1-OE2 3.13Å
570R98.6Very high98.8Very high140 Ų14040.6 Ų40.653%0.52820%0.202SC..Hα-helixtrans-67.4-33.1-177.7-77.7-171.2-60-83.6-0.1114D498 E566 F567D498-R570 PolarHBondContact O-NH2 2.87Å; E566-R570 WeakPolarHBondContact O-CG 3.24Å; E566-R570 PolarHBondContact O-N 2.56Å; E566-R570 VanDerWaalsContact O-N 3.07Å; E566-R570 PolarHBondContact O-NH1 3.42Å; F567-R570 PolarHBondContact O-N 3.37Å
571V98.6Very high98.8Very high63 Ų6341.2 Ų41.238%0.38221%0.206SC..Hα-helixtrans-91.4-3.5-177.1-57.60000113.3V532 F567 C568 R569V532-V571 HydrophobicContact CB-CG2 4.34Å; F567-V571 HydrophobicContact CD1-CG2 4.28Å; F567-V571 HydrophobicContact CD2-CG1 4.19Å; F567-V571 HydrophobicContact CE1-CG1 4.25Å; F567-V571 HydrophobicContact CE1-CG2 3.88Å; F567-V571 HydrophobicContact CE2-CG1 3.7Å; F567-V571 HydrophobicContact CZ-CG1 3.73Å; F567-V571 HydrophobicContact CZ-CG2 4.16Å; F567-V571 WeakPolarHBondContact O-CG2 3.29Å; F567-V571 PolarHBondContact O-N 3.41Å; C568-V571 PolarHBondContact O-N 3.1Å; R569-V571 PolarHBondContact O-N 3.12Å
572Q98.9Very high98.8Very high30 Ų3042.6 Ų42.614%0.1421%0.211CC..SBendtrans-62.8137.6170.3-163.6-178.631.800110.2C568 R569 G576 W578 E612C568-Q572 PolarHBondContact O-N 3.2Å; R569-Q572 PolarHBondContact O-N 2.78Å; Q572-G576 PolarHBondContact NE2-O 3.37Å; Q572-W578 HydrophobicContact CB-CD2 4.23Å; Q572-W578 VanDerWaalsContact CB-CE2 3.48Å; Q572-W578 HydrophobicContact CB-CH2 4.28Å; Q572-W578 HydrophobicContact CB-CZ2 3.48Å; Q572-W578 VanDerWaalsContact CB-CZ2 3.48Å; Q572-W578 VanDerWaalsContact CD-CH2 3.41Å; Q572-W578 HydrophobicContact CG-CD2 3.89Å; Q572-W578 HydrophobicContact CG-CE3 4.09Å; Q572-W578 HydrophobicContact CG-CH2 3.74Å; Q572-W578 HydrophobicContact CG-CZ2 3.44Å; Q572-W578 VanDerWaalsContact CG-CZ2 3.44Å; Q572-W578 HydrophobicContact CG-CZ3 4.06Å; Q572-W578 VanDerWaalsContact NE2-CZ3 3.3Å; Q572-E612 PolarHBondContact NE2-O 3.42Å; Q572-E612 VanDerWaalsContact OE1-CA 3.25Å
573R98.8Very high98.7Very high68 Ų6838.9 Ų38.926%0.25719%0.188SC..  trans-75.4162.8174.4-67.7-177.3169.9-156.21.7111.2D575 G576 S577 E579 R640R573-D575 VanDerWaalsContact CB-OD1 3.27Å; R573-D575 WeakPolarHBondContact CB-OD1 3.48Å; R573-D575 PolarHBondContact O-N 3.32Å; R573-G576 PolarHBondContact O-N 3.44Å; R573-S577 WeakPolarHBondContact CB-O 3.42Å; R573-S577 WeakPolarHBondContact CD-OG 3.26Å; R573-S577 PolarHBondContact N-O 3.24Å; R573-E579 IonicContact CZ-OE2 2.96Å; R573-E579 VanDerWaalsContact NH2-CD 3.26Å; R573-E579 IonicContact NH2-OE1 3.38Å; R573-E579 IonicContact NH2-OE2 3.6Å; R573-E579 PolarHBondContact NH2-OE2 3.36Å; R573-R640 PolarHBondContact NH1-O 3.12Å; R573-R640 PolarHBondContact NH2-O 2.88Å
574T98.2Very high98.7Very high132 Ų13235.9 Ų35.981%0.8117%0.172SC*.THydrogen-bonded Turntrans-62.6-31.3-178.547.90000113.4G576 K615T574-G576 PolarHBondContact O-N 3.3Å; T574-K615 PolarHBondContact O-NZ 3.13Å
575D98.4Very high98.7Very high78 Ų7835.9 Ų35.942%0.41717%0.172SC..THydrogen-bonded Turntrans-74.5-8174.161.117.3000113.7R573 S577 F619R573-D575 VanDerWaalsContact CB-OD1 3.27Å; R573-D575 WeakPolarHBondContact CB-OD1 3.48Å; R573-D575 PolarHBondContact O-N 3.32Å; D575-S577 WeakPolarHBondContact OD1-CB 3.14Å; D575-S577 PolarHBondContact OD1-N 2.91Å; D575-S577 PolarHBondContact OD1-OG 2.78Å; D575-F619 HydrophobicContact CB-CD2 4.39Å
576G98.8Very high98.7Very high0 Ų035.4 Ų35.40%017%0.169CC..SBendtrans96.9-11.1-179.300000114.9Q572 R573 T574 A616Q572-G576 PolarHBondContact NE2-O 3.37Å; R573-G576 PolarHBondContact O-N 3.44Å; T574-G576 PolarHBondContact O-N 3.3Å; G576-A616 WeakPolarHBondContact O-CA 3.35Å; G576-A616 WeakPolarHBondContact O-CB 3.2Å
577S98.9Very high98.7Very high0 Ų032.1 Ų32.10%015%0.154CC..  trans-76.9161.5-18069.30000112.6R573 D575R573-S577 WeakPolarHBondContact CB-O 3.42Å; R573-S577 WeakPolarHBondContact CD-OG 3.26Å; R573-S577 PolarHBondContact N-O 3.24Å; D575-S577 WeakPolarHBondContact OD1-CB 3.14Å; D575-S577 PolarHBondContact OD1-N 2.91Å; D575-S577 PolarHBondContact OD1-OG 2.78Å
578W98.9Very high98.7Very high2 Ų231.9 Ų31.91%0.00815%0.153CC..  trans-117.1137.3160.3-74.3-93.6000109.6V532 C568 Q572 F586 G589 T590 F597 A616V532-W578 HydrophobicContact CG1-CB 4.07Å; V532-W578 HydrophobicContact CG1-CG 4.35Å; V532-W578 HydrophobicContact CG2-CG 4.12Å; C568-W578 PolarHBondContact O-NE1 3.14Å; Q572-W578 HydrophobicContact CB-CD2 4.23Å; Q572-W578 VanDerWaalsContact CB-CE2 3.48Å; Q572-W578 HydrophobicContact CB-CH2 4.28Å; Q572-W578 HydrophobicContact CB-CZ2 3.48Å; Q572-W578 VanDerWaalsContact CB-CZ2 3.48Å; Q572-W578 VanDerWaalsContact CD-CH2 3.41Å; Q572-W578 HydrophobicContact CG-CD2 3.89Å; Q572-W578 HydrophobicContact CG-CE3 4.09Å; Q572-W578 HydrophobicContact CG-CH2 3.74Å; Q572-W578 HydrophobicContact CG-CZ2 3.44Å; Q572-W578 VanDerWaalsContact CG-CZ2 3.44Å; Q572-W578 HydrophobicContact CG-CZ3 4.06Å; Q572-W578 VanDerWaalsContact NE2-CZ3 3.3Å; W578-F586 WeakPolarHBondContact O-CA 3.28Å; W578-G589 WeakPolarHBondContact CB-O 3.42Å; W578-T590 HydrophobicContact CE3-CG2 4.15Å; W578-T590 HydrophobicContact CZ3-CG2 4.47Å; W578-T590 PolarHBondContact N-OG1 3.01Å; W578-T590 VanDerWaalsContact N-OG1 3.09Å; W578-F597 HydrophobicContact CH2-CD2 4.19Å; W578-F597 AromaticContact CH2-CE2 3.85Å; W578-F597 HydrophobicContact CH2-CE2 3.85Å; W578-F597 HydrophobicContact CZ2-CD2 4.43Å; W578-F597 AromaticContact CZ2-CE2 3.77Å; W578-F597 HydrophobicContact CZ2-CE2 3.77Å; W578-A616 HydrophobicContact CE3-CB 4.41Å; W578-A616 HydrophobicContact CH2-CB 4.43Å; W578-A616 HydrophobicContact CZ3-CB 3.61Å
579E98.9Very high98.7Very high28 Ų2831.9 Ų31.913%0.13115%0.153CC..  trans-78.7119176.9-178.4-179.4-174.900110R573 F586 R640 K699R573-E579 IonicContact CZ-OE2 2.96Å; R573-E579 VanDerWaalsContact NH2-CD 3.26Å; R573-E579 IonicContact NH2-OE1 3.38Å; R573-E579 IonicContact NH2-OE2 3.6Å; R573-E579 PolarHBondContact NH2-OE2 3.36Å; E579-F586 HydrophobicContact CB-CE1 3.89Å; E579-F586 HydrophobicContact CB-CZ 4.34Å; E579-F586 HydrophobicContact CG-CE1 4.28Å; E579-F586 HydrophobicContact CG-CZ 4.23Å; E579-R640 WeakPolarHBondContact OE1-CG 3.46Å; E579-R640 IonicContact OE1-CZ 2.76Å; E579-R640 IonicContact OE1-NE 3.77Å; E579-R640 PolarHBondContact OE1-NE 3.35Å; E579-R640 IonicContact OE1-NH2 3.36Å; E579-R640 PolarHBondContact OE1-NH2 2.87Å; E579-R640 IonicContact OE2-CZ 3.68Å; E579-R640 IonicContact OE2-NE 3.84Å; E579-R640 PolarHBondContact OE2-NE 2.88Å; E579-R640 IonicContact OE2-NH2 3.99Å; E579-R640 PolarHBondContact OE2-NH2 3.27Å; E579-K699 VanDerWaalsContact OE1-CE 3.31Å; E579-K699 WeakPolarHBondContact OE1-CE 3.4Å
580G98.7Very high98.7Very high1 Ų128.2 Ų28.21%0.0114%0.139CC..  trans-72.8137.6171.800000111.6E533 C585E533-G580 WeakPolarHBondContact OE1-CA 3.26Å; G580-C585 WeakPolarHBondContact CA-O 3.27Å; G580-C585 PolarHBondContact N-O 2.85Å
581S98.7Very high98.7Very high14 Ų1421.8 Ų21.810%0.09812%0.115CC..SBendtrans-111.7-13.4178.6-63.50000113.6Y531 E533Y531-S581 WeakPolarHBondContact CD1-OG 3.43Å; Y531-S581 VanDerWaalsContact CE1-CB 3.47Å; Y531-S581 WeakPolarHBondContact CE1-OG 2.99Å; E533-S581 PolarHBondContact OE1-N 3.12Å
582W98.7Very high98.7Very high34 Ų3418.9 Ų18.913%0.12910%0.097CC..SBendtrans-122.6-11-177.6-53104.8000114.2W231 T503 Y531 Y588 V696 F697W231-W582 HydrophobicContact CZ2-CH2 4.1Å; T503-W582 HydrophobicContact CG2-CH2 3.93Å; T503-W582 HydrophobicContact CG2-CZ2 3.26Å; Y531-W582 AromaticContact CD1-NE1 3.97Å; Y531-W582 HydrophobicContact CD2-CZ2 4.17Å; Y531-W582 AromaticContact CD2-NE1 3.66Å; Y531-W582 HydrophobicContact CE1-CZ2 4.48Å; Y531-W582 AromaticContact CE2-CZ2 3.6Å; Y531-W582 HydrophobicContact CE2-CZ2 3.6Å; Y531-W582 AromaticContact CE2-NE1 3.95Å; Y531-W582 AromaticContact CG-NE1 3.66Å; Y531-W582 AromaticContact CZ-CZ2 3.76Å; W582-Y588 HydrophobicContact CB-CE1 4.1Å; W582-V696 CarbonylContact C-O 3.45Å; W582-V696 VanDerWaalsContact CA-O 3.32Å; W582-V696 WeakPolarHBondContact CA-O 3.38Å; W582-V696 PolarHBondContact O-N 2.85Å; W582-F697 HydrophobicContact CE3-CB 4.38Å; W582-F697 HydrophobicContact CZ3-CB 4.01Å
583G98.8Very high98.7Very high0 Ų017.5 Ų17.50%09%0.09CC..BIsolated β-bridgetrans-142.3150.1173.600000109.9C585 S694G583-C585 VanDerWaalsContact O-CA 3.25Å; G583-C585 WeakPolarHBondContact O-CA 3.43Å; G583-S694 CarbonylContact C-O 3.51Å; G583-S694 VanDerWaalsContact CA-O 3.32Å; G583-S694 WeakPolarHBondContact CA-O 3.49Å
584V98.8Very high98.7Very high0 Ų014.2 Ų14.20%08%0.078CC..SBendtrans-85.5109.9-171.2178.80000111.2E632 F634 N652 W655 S694 V696V584-E632 HydrophobicContact CG1-CB 4.3Å; V584-F634 HydrophobicContact CG2-CD2 3.86Å; V584-F634 HydrophobicContact CG2-CE2 4.38Å; V584-N652 PolarHBondContact O-ND2 3.25Å; V584-W655 WeakPolarHBondContact O-CZ3 3.47Å; V584-S694 PolarHBondContact N-O 2.99Å; V584-V696 HydrophobicContact CG2-CB 4.09Å; V584-V696 HydrophobicContact CG2-CG1 4.31Å
585C97.3Very high98.8Very high0 Ų08.8 Ų8.80%04%0.043CC..SBendcis-140.3-71.9-16.4177.10000107.6G580 G583 Y588 G589 E632G580-C585 WeakPolarHBondContact CA-O 3.27Å; G580-C585 PolarHBondContact N-O 2.85Å; G583-C585 VanDerWaalsContact O-CA 3.25Å; G583-C585 WeakPolarHBondContact O-CA 3.43Å; C585-Y588 WeakPolarHBondContact O-CB 3.34Å; C585-Y588 PolarHBondContact O-N 3.31Å; C585-G589 PolarHBondContact O-N 3.4Å; C585-E632 WeakPolarHBondContact CB-OE2 3.28Å; C585-E632 PolarHBondContact N-OE1 3.09Å; C585-E632 PolarHBondContact N-OE2 3.12Å
586F98.9Very high98.8Very high2 Ų25 Ų51%0.0092%0.024CC..Hα-helixtrans-79.2-35.2-174.9-67.8-83000113.2W578 E579 Y588 T590 F619 E632 R641 Y642W578-F586 WeakPolarHBondContact O-CA 3.28Å; E579-F586 HydrophobicContact CB-CE1 3.89Å; E579-F586 HydrophobicContact CB-CZ 4.34Å; E579-F586 HydrophobicContact CG-CE1 4.28Å; E579-F586 HydrophobicContact CG-CZ 4.23Å; F586-Y588 VanDerWaalsContact C-N 3.27Å; F586-Y588 PolarHBondContact O-N 3.03Å; F586-T590 WeakPolarHBondContact O-CB 3.37Å; F586-T590 PolarHBondContact O-N 3.29Å; F586-T590 PolarHBondContact O-OG1 2.83Å; F586-F619 HydrophobicContact CB-CE1 3.83Å; F586-F619 HydrophobicContact CB-CZ 3.83Å; F586-F619 HydrophobicContact CD1-CZ 4.44Å; F586-F619 HydrophobicContact CG-CZ 4.2Å; F586-E632 WeakPolarHBondContact CD2-OE2 3.43Å; F586-E632 PolarHBondContact N-OE1 2.64Å; F586-E632 PolarHBondContact N-OE2 3.14Å; F586-R641 VanDerWaalsContact CE2-CA 3.42Å; F586-R641 WeakPolarHBondContact CE2-O 3.44Å; F586-Y642 HydrophobicContact CB-CD2 3.9Å; F586-Y642 HydrophobicContact CB-CE2 4.48Å; F586-Y642 HydrophobicContact CD2-CD2 4.32Å; F586-Y642 HydrophobicContact CG-CD2 4.4Å
587T98.9Very high98.8Very high0 Ų05 Ų50%02%0.024CC..Hα-helixtrans-60.8-40.4171.249.50000110.9W591 L620 W630 E632 Y642 N652 A656T587-W591 WeakPolarHBondContact O-CB 3.37Å; T587-W591 PolarHBondContact O-N 3.33Å; T587-L620 HydrophobicContact CG2-CD2 4.2Å; T587-W630 HydrophobicContact CG2-CB 4.21Å; T587-W630 HydrophobicContact CG2-CG 4.41Å; T587-E632 VanDerWaalsContact CB-OE1 3.29Å; T587-E632 WeakPolarHBondContact CB-OE1 3.17Å; T587-E632 WeakPolarHBondContact CG2-OE1 3.44Å; T587-E632 PolarHBondContact N-OE1 2.95Å; T587-E632 PolarHBondContact OG1-OE1 3.3Å; T587-Y642 HydrophobicContact CG2-CE2 4.18Å; T587-N652 HydrophobicContact CG2-CB 4.17Å; T587-N652 PolarHBondContact OG1-ND2 2.69Å; T587-A656 HydrophobicContact CG2-CB 4.31Å
588Y98.9Very high98.8Very high1 Ų16 Ų60%0.0043%0.031CC..Hα-helixtrans-63.8-58.2176.2-173.3-106.1000112.3E533 W582 C585 F586 T590 W591 F592 W655E533-Y588 HydrophobicContact CB-CE1 4.33Å; E533-Y588 HydrophobicContact CG-CD1 4.01Å; E533-Y588 HydrophobicContact CG-CE1 3.62Å; W582-Y588 HydrophobicContact CB-CE1 4.1Å; C585-Y588 WeakPolarHBondContact O-CB 3.34Å; C585-Y588 PolarHBondContact O-N 3.31Å; F586-Y588 VanDerWaalsContact C-N 3.27Å; F586-Y588 PolarHBondContact O-N 3.03Å; Y588-T590 VanDerWaalsContact C-N 3.29Å; Y588-T590 PolarHBondContact O-N 3.28Å; Y588-W591 HydrophobicContact CD2-CE3 4.29Å; Y588-W591 HydrophobicContact CD2-CZ3 4.43Å; Y588-W591 HydrophobicContact CE2-CE3 4.45Å; Y588-W591 HydrophobicContact CE2-CZ3 4.17Å; Y588-W591 WeakPolarHBondContact O-CB 3.22Å; Y588-W591 PolarHBondContact O-N 3.08Å; Y588-F592 HydrophobicContact CD1-CD2 4.4Å; Y588-F592 HydrophobicContact CD1-CE2 4.45Å; Y588-F592 HydrophobicContact CD2-CE2 4.19Å; Y588-F592 HydrophobicContact CE1-CD2 4.15Å; Y588-F592 AromaticContact CE1-CE2 3.88Å; Y588-F592 HydrophobicContact CE1-CE2 3.88Å; Y588-F592 HydrophobicContact CE2-CD2 4.32Å; Y588-F592 AromaticContact CE2-CE2 3.57Å; Y588-F592 HydrophobicContact CE2-CE2 3.57Å; Y588-F592 AromaticContact CZ-CE2 3.38Å; Y588-F592 WeakPolarHBondContact O-CD2 3.45Å; Y588-F592 PolarHBondContact O-N 3.49Å; Y588-F592 WeakPolarHBondContact OH-CE2 3.48Å; Y588-W655 AromaticContact CD2-CD2 3.82Å; Y588-W655 HydrophobicContact CD2-CD2 3.82Å; Y588-W655 AromaticContact CD2-CE2 3.59Å; Y588-W655 HydrophobicContact CD2-CE3 4Å; Y588-W655 HydrophobicContact CD2-CG 4.5Å; Y588-W655 AromaticContact CD2-CH2 3.74Å; Y588-W655 HydrophobicContact CD2-CH2 3.74Å; Y588-W655 AromaticContact CD2-CZ2 3.55Å; Y588-W655 HydrophobicContact CD2-CZ2 3.55Å; Y588-W655 AromaticContact CD2-CZ3 3.96Å; Y588-W655 HydrophobicContact CD2-CZ3 3.96Å; Y588-W655 HydrophobicContact CE2-CH2 4.48Å; Y588-W655 HydrophobicContact CE2-CZ2 4.05Å; Y588-W655 HydrophobicContact CG-CE3 4.33Å; Y588-W655 HydrophobicContact CG-CH2 4.35Å; Y588-W655 HydrophobicContact CG-CZ3 4.24Å
589G98.9Very high98.8Very high0 Ų07.3 Ų7.30%04%0.041CC..Hα-helixtrans-60-40.3179.900000112.3W578 C585 F592 G593W578-G589 WeakPolarHBondContact CB-O 3.42Å; C585-G589 PolarHBondContact O-N 3.4Å; G589-F592 PolarHBondContact O-N 3.31Å; G589-G593 PolarHBondContact O-N 3.12Å
590T98.9Very high98.7Very high0 Ų08.5 Ų8.50%05%0.047CC..Hα-helixtrans-70.1-34.2-179.7-54.80000112.5W578 F586 Y588 G593 L594 A616 L620W578-T590 HydrophobicContact CE3-CG2 4.15Å; W578-T590 HydrophobicContact CZ3-CG2 4.47Å; W578-T590 PolarHBondContact N-OG1 3.01Å; W578-T590 VanDerWaalsContact N-OG1 3.09Å; F586-T590 WeakPolarHBondContact O-CB 3.37Å; F586-T590 PolarHBondContact O-N 3.29Å; F586-T590 PolarHBondContact O-OG1 2.83Å; Y588-T590 VanDerWaalsContact C-N 3.29Å; Y588-T590 PolarHBondContact O-N 3.28Å; T590-G593 PolarHBondContact O-N 3.09Å; T590-L594 HydrophobicContact CG2-CD1 4.08Å; T590-L594 HydrophobicContact CG2-CG 4.36Å; T590-L594 WeakPolarHBondContact O-CB 3.33Å; T590-L594 WeakPolarHBondContact O-CG 3.48Å; T590-L594 PolarHBondContact O-N 3.03Å; T590-A616 HydrophobicContact CG2-CB 3.87Å; T590-L620 HydrophobicContact CG2-CD1 3.99Å; T590-L620 HydrophobicContact CG2-CD2 4.12Å; T590-L620 HydrophobicContact CG2-CG 3.97Å
591W98.9Very high98.7Very high5 Ų510.6 Ų10.62%0.0197%0.068CC..Hα-helixtrans-57.4-52.4170.2166.941.8000111.1T587 Y588 G593 L594 E595 W655 L658 F712T587-W591 WeakPolarHBondContact O-CB 3.37Å; T587-W591 PolarHBondContact O-N 3.33Å; Y588-W591 HydrophobicContact CD2-CE3 4.29Å; Y588-W591 HydrophobicContact CD2-CZ3 4.43Å; Y588-W591 HydrophobicContact CE2-CE3 4.45Å; Y588-W591 HydrophobicContact CE2-CZ3 4.17Å; Y588-W591 WeakPolarHBondContact O-CB 3.22Å; Y588-W591 PolarHBondContact O-N 3.08Å; W591-G593 VanDerWaalsContact C-N 3.34Å; W591-G593 PolarHBondContact O-N 3.31Å; W591-L594 PolarHBondContact O-N 3.31Å; W591-E595 VanDerWaalsContact NE1-CG 3.32Å; W591-E595 PolarHBondContact NE1-OE1 3.43Å; W591-E595 WeakPolarHBondContact O-CG 3.34Å; W591-E595 PolarHBondContact O-N 3.04Å; W591-W655 HydrophobicContact CB-CB 3.93Å; W591-W655 WeakPolarHBondContact CB-O 3.46Å; W591-W655 HydrophobicContact CD2-CG 4.49Å; W591-W655 HydrophobicContact CE3-CB 4.4Å; W591-W655 AromaticContact CE3-CD1 3.4Å; W591-W655 VanDerWaalsContact CE3-CD1 3.4Å; W591-W655 AromaticContact CE3-CG 3.96Å; W591-W655 HydrophobicContact CE3-CG 3.96Å; W591-W655 AromaticContact CE3-NE1 3.93Å; W591-W655 HydrophobicContact CG-CB 4.33Å; W591-W655 AromaticContact CZ3-CD1 3.76Å; W591-W655 AromaticContact CZ3-NE1 3.88Å; W591-L658 HydrophobicContact CG-CB 4.33Å; W591-L658 HydrophobicContact CZ2-CD1 4.13Å; W591-F712 AromaticContact CH2-CE1 3.46Å; W591-F712 HydrophobicContact CH2-CE1 3.46Å; W591-F712 VanDerWaalsContact CH2-CE1 3.46Å; W591-F712 AromaticContact CH2-CZ 3.93Å; W591-F712 HydrophobicContact CH2-CZ 3.93Å; W591-F712 HydrophobicContact CZ2-CE1 4.18Å; W591-F712 AromaticContact CZ3-CE1 3.63Å; W591-F712 HydrophobicContact CZ3-CE1 3.63Å; W591-F712 AromaticContact CZ3-CZ 3.81Å; W591-F712 HydrophobicContact CZ3-CZ 3.81Å
592F98.9Very high98.6Very high2 Ų212.6 Ų12.61%0.0098%0.076CC..Hα-helixtrans-61.5-40.4177.4-83.7-79.3000112.9F392 E533 S536 A537 Y588 G589 E595 A596F392-F592 HydrophobicContact CZ-CZ 4.47Å; E533-F592 HydrophobicContact CB-CB 4.36Å; E533-F592 HydrophobicContact CB-CD1 4.18Å; E533-F592 HydrophobicContact CB-CD2 3.81Å; E533-F592 HydrophobicContact CB-CE1 4.42Å; E533-F592 HydrophobicContact CB-CE2 4.11Å; E533-F592 HydrophobicContact CB-CG 3.85Å; E533-F592 HydrophobicContact CB-CZ 4.39Å; E533-F592 HydrophobicContact CG-CB 4.18Å; E533-F592 HydrophobicContact CG-CD2 3.64Å; E533-F592 HydrophobicContact CG-CE2 4.21Å; E533-F592 HydrophobicContact CG-CG 3.95Å; S536-F592 WeakPolarHBondContact CB-O 3.12Å; S536-F592 PolarHBondContact OG-O 3.27Å; A537-F592 HydrophobicContact CB-CE1 4.41Å; Y588-F592 HydrophobicContact CD1-CD2 4.4Å; Y588-F592 HydrophobicContact CD1-CE2 4.45Å; Y588-F592 HydrophobicContact CD2-CE2 4.19Å; Y588-F592 HydrophobicContact CE1-CD2 4.15Å; Y588-F592 AromaticContact CE1-CE2 3.88Å; Y588-F592 HydrophobicContact CE1-CE2 3.88Å; Y588-F592 HydrophobicContact CE2-CD2 4.32Å; Y588-F592 AromaticContact CE2-CE2 3.57Å; Y588-F592 HydrophobicContact CE2-CE2 3.57Å; Y588-F592 AromaticContact CZ-CE2 3.38Å; Y588-F592 WeakPolarHBondContact O-CD2 3.45Å; Y588-F592 PolarHBondContact O-N 3.49Å; Y588-F592 WeakPolarHBondContact OH-CE2 3.48Å; G589-F592 PolarHBondContact O-N 3.31Å; F592-E595 PolarHBondContact O-N 3.19Å; F592-A596 PolarHBondContact O-N 3.07Å
593G98.9Very high98.6Very high0 Ų012 Ų120%08%0.077CC..Hα-helixtrans-56.5-51.3173.700000111.7G589 T590 W591 E595 A596 F597G589-G593 PolarHBondContact O-N 3.12Å; T590-G593 PolarHBondContact O-N 3.09Å; W591-G593 VanDerWaalsContact C-N 3.34Å; W591-G593 PolarHBondContact O-N 3.31Å; G593-E595 PolarHBondContact O-N 2.89Å; G593-A596 WeakPolarHBondContact O-CB 3.22Å; G593-A596 PolarHBondContact O-N 3.11Å; G593-F597 WeakPolarHBondContact O-CD2 3.38Å; G593-F597 PolarHBondContact O-N 2.76Å
594L98.9Very high98.5Very high0 Ų014.9 Ų14.90%09%0.088CC..Hα-helixtrans-63.5-38.7178.9-72.3171.5000112.9T590 W591 A596 F597 A598 V613 A616 L620 V663T590-L594 HydrophobicContact CG2-CD1 4.08Å; T590-L594 HydrophobicContact CG2-CG 4.36Å; T590-L594 WeakPolarHBondContact O-CB 3.33Å; T590-L594 WeakPolarHBondContact O-CG 3.48Å; T590-L594 PolarHBondContact O-N 3.03Å; W591-L594 PolarHBondContact O-N 3.31Å; L594-A596 VanDerWaalsContact C-N 3.34Å; L594-A596 PolarHBondContact O-N 3.05Å; L594-F597 PolarHBondContact O-N 2.9Å; L594-A598 WeakPolarHBondContact O-CB 3.24Å; L594-A598 PolarHBondContact O-N 3.09Å; L594-V613 HydrophobicContact CD2-CG1 4.18Å; L594-A616 HydrophobicContact CD1-CB 4.38Å; L594-A616 HydrophobicContact CD2-CB 3.73Å; L594-A616 HydrophobicContact CG-CB 4.1Å; L594-L620 HydrophobicContact CD1-CD1 3.72Å; L594-V663 HydrophobicContact CB-CG1 4.12Å; L594-V663 HydrophobicContact CD2-CG1 3.82Å; L594-V663 HydrophobicContact CD2-CG2 4.09Å
595E98.9Very high98.2Very high17 Ų1723 Ų238%0.07912%0.123CC..Hα-helixtrans-63-38.3174.6-68.7-76.1-165.400112.4W591 F592 G593 F597 A598 C599 A662 R719W591-E595 VanDerWaalsContact NE1-CG 3.32Å; W591-E595 PolarHBondContact NE1-OE1 3.43Å; W591-E595 WeakPolarHBondContact O-CG 3.34Å; W591-E595 PolarHBondContact O-N 3.04Å; F592-E595 PolarHBondContact O-N 3.19Å; G593-E595 PolarHBondContact O-N 2.89Å; E595-F597 PolarHBondContact O-N 2.74Å; E595-A598 PolarHBondContact O-N 3.49Å; E595-C599 WeakPolarHBondContact O-CB 3.48Å; E595-C599 PolarHBondContact O-N 3.28Å; E595-A662 HydrophobicContact CG-CB 4.38Å; E595-A662 WeakPolarHBondContact OE2-CB 3.46Å; E595-R719 IonicContact OE1-CZ 3.51Å; E595-R719 IonicContact OE1-NH1 3.78Å; E595-R719 PolarHBondContact OE1-NH1 3.49Å; E595-R719 IonicContact OE1-NH2 3.07Å; E595-R719 PolarHBondContact OE1-NH2 2.84Å; E595-R719 VanDerWaalsContact OE1-NH2 3.15Å
596A98.9Very high97.7Very high0 Ų024.8 Ų24.80%014%0.138CC..Hα-helixtrans-64.2-40.817700000111.9S536 M539 F592 G593 L594 C599 M600S536-A596 PolarHBondContact OG-N 3.04Å; M539-A596 HydrophobicContact CE-CB 4.02Å; M539-A596 HydrophobicContact SD-CB 4.12Å; F592-A596 PolarHBondContact O-N 3.07Å; G593-A596 WeakPolarHBondContact O-CB 3.22Å; G593-A596 PolarHBondContact O-N 3.11Å; L594-A596 VanDerWaalsContact C-N 3.34Å; L594-A596 PolarHBondContact O-N 3.05Å; A596-C599 PolarHBondContact O-SG 2.93Å; A596-M600 WeakPolarHBondContact O-CG 3.43Å
597F98.9Very high97Very high0 Ų034.6 Ų34.60%018%0.184CC..Hα-helixtrans-67.7-44.1173.8-84.4-97.8000111.2L565 C568 R569 W578 G593 L594 E595 C599 M600 G601 H602 P610 E612 V613L565-F597 HydrophobicContact CD1-CD1 3.96Å; L565-F597 HydrophobicContact CD1-CD2 3.98Å; L565-F597 HydrophobicContact CD1-CE1 4.05Å; L565-F597 HydrophobicContact CD1-CE2 4.08Å; L565-F597 HydrophobicContact CD1-CG 3.93Å; L565-F597 HydrophobicContact CD1-CZ 4.11Å; C568-F597 HydrophobicContact CB-CE2 4.32Å; R569-F597 HydrophobicContact CB-CZ 4.34Å; W578-F597 HydrophobicContact CH2-CD2 4.19Å; W578-F597 AromaticContact CH2-CE2 3.85Å; W578-F597 HydrophobicContact CH2-CE2 3.85Å; W578-F597 HydrophobicContact CZ2-CD2 4.43Å; W578-F597 AromaticContact CZ2-CE2 3.77Å; W578-F597 HydrophobicContact CZ2-CE2 3.77Å; G593-F597 WeakPolarHBondContact O-CD2 3.38Å; G593-F597 PolarHBondContact O-N 2.76Å; L594-F597 PolarHBondContact O-N 2.9Å; E595-F597 PolarHBondContact O-N 2.74Å; F597-C599 PolarHBondContact O-N 2.53Å; F597-M600 CarbonylContact O-C 3.55Å; F597-M600 PolarHBondContact O-N 2.52Å; F597-G601 PolarHBondContact O-N 3.24Å; F597-H602 HydrophobicContact CB-CB 4.08Å; F597-H602 HydrophobicContact CD1-CB 3.97Å; F597-H602 AromaticContact CD1-CD2 3.99Å; F597-H602 WeakPolarHBondContact O-CB 3.36Å; F597-H602 PolarHBondContact O-N 3.26Å; F597-P610 HydrophobicContact CE1-CB 4.39Å; F597-E612 HydrophobicContact CE1-CB 3.8Å; F597-E612 HydrophobicContact CE1-CG 4.26Å; F597-E612 HydrophobicContact CE2-CB 4.29Å; F597-E612 HydrophobicContact CZ-CB 3.58Å; F597-E612 HydrophobicContact CZ-CG 3.88Å; F597-V613 HydrophobicContact CB-CG2 3.75Å; F597-V613 HydrophobicContact CD1-CG2 3.67Å; F597-V613 HydrophobicContact CE1-CG2 4.48Å; F597-V613 HydrophobicContact CG-CG2 3.81Å
598A98.8Very high96.6Very high19 Ų1942.5 Ų42.516%0.15722%0.221CC..Hα-helixtrans-62.2-43.1-179.700000112.6L594 E595 M600 G601 T603 A662 V663L594-A598 WeakPolarHBondContact O-CB 3.24Å; L594-A598 PolarHBondContact O-N 3.09Å; E595-A598 PolarHBondContact O-N 3.49Å; A598-M600 PolarHBondContact O-N 2.89Å; A598-G601 PolarHBondContact O-N 3.02Å; A598-T603 HydrophobicContact CB-CG2 4.43Å; A598-A662 HydrophobicContact CB-CB 4Å; A598-V663 HydrophobicContact CB-CG1 4.11Å
599C98.3Very high96.4Very high31 Ų3144 Ų4421%0.20923%0.229CC..Hα-helixtrans-67-20.3179.580.70000113.1Q540 E595 A596 F597Q540-C599 HydrophobicContact CG-CB 4.18Å; E595-C599 WeakPolarHBondContact O-CB 3.48Å; E595-C599 PolarHBondContact O-N 3.28Å; A596-C599 PolarHBondContact O-SG 2.93Å; F597-C599 PolarHBondContact O-N 2.53Å
600M98.3Very high96.4Very high53 Ų5345 Ų4526%0.26124%0.236SC..THydrogen-bonded Turntrans-902.1173-64.1-61.1-73.300113.3M539 L561 L565 A596 F597 A598M539-M600 HydrophobicContact CE-CG 3.68Å; M539-M600 HydrophobicContact CE-SD 4.25Å; L561-M600 HydrophobicContact CB-CE 4.03Å; L561-M600 HydrophobicContact CB-SD 3.9Å; L565-M600 HydrophobicContact CB-CG 4.36Å; L565-M600 HydrophobicContact CD1-CB 4.48Å; L565-M600 HydrophobicContact CD1-CG 4.27Å; L565-M600 HydrophobicContact CD2-CB 4.02Å; L565-M600 HydrophobicContact CD2-CE 4.35Å; L565-M600 HydrophobicContact CD2-CG 4.08Å; L565-M600 HydrophobicContact CG-CG 4.47Å; A596-M600 WeakPolarHBondContact O-CG 3.43Å; F597-M600 CarbonylContact O-C 3.55Å; F597-M600 PolarHBondContact O-N 2.52Å; A598-M600 PolarHBondContact O-N 2.89Å
601G97.3Very high96.3Very high45 Ų4548.7 Ų48.746%0.46426%0.259SS..THydrogen-bonded Turntrans90.43.7176.500000114.8F597 A598 T603F597-G601 PolarHBondContact O-N 3.24Å; A598-G601 PolarHBondContact O-N 3.02Å; G601-T603 PolarHBondContact O-N 3.09Å; G601-T603 VanDerWaalsContact O-N 3.15Å
602H98.1Very high96.3Very high55 Ų5549.6 Ų49.626%0.25526%0.263SS..  trans-83.191.2179-62.6-57.4000111L565 F597 P610 V613L565-H602 WeakPolarHBondContact CD2-NE2 3.35Å; F597-H602 HydrophobicContact CB-CB 4.08Å; F597-H602 HydrophobicContact CD1-CB 3.97Å; F597-H602 AromaticContact CD1-CD2 3.99Å; F597-H602 WeakPolarHBondContact O-CB 3.36Å; F597-H602 PolarHBondContact O-N 3.26Å; H602-P610 HydrophobicContact CB-CG 3.79Å; H602-V613 HydrophobicContact CB-CG2 4.45Å
603T97.9Very high96.3Very high23 Ų2349.5 Ų49.514%0.14126%0.263CS..SBendtrans-133.6167.2-178.2720000110.9A598 G601 K605 A606 V663A598-T603 HydrophobicContact CB-CG2 4.43Å; G601-T603 PolarHBondContact O-N 3.09Å; G601-T603 VanDerWaalsContact O-N 3.15Å; T603-K605 PolarHBondContact O-N 3.19Å; T603-K605 VanDerWaalsContact O-N 3.15Å; T603-K605 PolarHBondContact OG1-N 3.48Å; T603-A606 VanDerWaalsContact O-CB 3.31Å; T603-A606 WeakPolarHBondContact O-CB 3.47Å; T603-A606 PolarHBondContact O-N 3.31Å; T603-V663 WeakPolarHBondContact CA-O 3.04Å; T603-V663 WeakPolarHBondContact CB-O 3.39Å
604Y97.4Very high96.3Very high60 Ų6053.3 Ų53.324%0.23528%0.28CS..THydrogen-bonded Turntrans-67.2-6.5173.6-81.5-95.6000114.7V609 V613 Q614 C617 V663 R664 H665 P666Y604-V609 HydrophobicContact CD1-CG1 4.2Å; Y604-V609 HydrophobicContact CD1-CG2 3.95Å; Y604-V609 HydrophobicContact CD2-CG1 4.08Å; Y604-V609 HydrophobicContact CE1-CG1 4.16Å; Y604-V609 HydrophobicContact CE1-CG2 4.48Å; Y604-V609 HydrophobicContact CE2-CG1 4.02Å; Y604-V609 HydrophobicContact CG-CG1 4.18Å; Y604-V609 HydrophobicContact CG-CG2 4.18Å; Y604-V613 HydrophobicContact CD2-CG1 4.19Å; Y604-V613 HydrophobicContact CE2-CG1 3.74Å; Y604-Q614 WeakPolarHBondContact OH-CA 3.25Å; Y604-C617 HydrophobicContact CE2-CB 4.48Å; Y604-V663 HydrophobicContact CD2-CB 4.48Å; Y604-V663 HydrophobicContact CD2-CG2 4.21Å; Y604-V663 WeakPolarHBondContact CD2-O 3.19Å; Y604-V663 HydrophobicContact CE2-CG2 4.31Å; Y604-V663 PolarHBondContact N-O 3.06Å; Y604-R664 WeakPolarHBondContact CB-O 3.47Å; Y604-H665 HydrophobicContact CD2-CB 4.48Å; Y604-H665 AromaticContact CE2-CD2 3.59Å; Y604-H665 AromaticContact CZ-CD2 3.59Å; Y604-P666 HydrophobicContact CD1-CG 4.13Å; Y604-P666 HydrophobicContact CE1-CG 4.42Å
605K91.8Very high96.3Very high169 Ų16957 Ų5774%0.73530%0.297SS*.THydrogen-bonded Turntrans-88.2-11170.5-69.7-171.4175.7-175.10113.3T603 R664T603-K605 PolarHBondContact O-N 3.19Å; T603-K605 VanDerWaalsContact O-N 3.15Å; T603-K605 PolarHBondContact OG1-N 3.48Å; K605-R664 HydrophobicContact CD-CG 4.28Å; K605-R664 HydrophobicContact CG-CB 4.15Å; K605-R664 HydrophobicContact CG-CG 4.34Å
606A87.4Confident96.3Very high38 Ų3856.2 Ų56.231%0.31429%0.293SS..SBendtrans-73.9159.6175.400000110.8T603 E608T603-A606 VanDerWaalsContact O-CB 3.31Å; T603-A606 WeakPolarHBondContact O-CB 3.47Å; T603-A606 PolarHBondContact O-N 3.31Å; A606-E608 VanDerWaalsContact C-N 3.25Å; A606-E608 PolarHBondContact O-N 3.29Å
607E83.4Confident96.3Very high208 Ų20856.2 Ų56.297%0.97229%0.293SS*.SBendtrans-59.4-38.8177.1-65.4-177.9176.600111.8
608E91.5Very high96.3Very high167 Ų16762.7 Ų62.778%0.7832%0.317SS*.SBendtrans-125.6126.3176.2-65.5-174172.900110.8A606A606-E608 VanDerWaalsContact C-N 3.25Å; A606-E608 PolarHBondContact O-N 3.29Å
609V95.1Very high96.3Very high31 Ų3162.1 Ų62.119%0.18831%0.311CS..  trans-94.9120.7177-170.70000109Y604 V613 Q614Y604-V609 HydrophobicContact CD1-CG1 4.2Å; Y604-V609 HydrophobicContact CD1-CG2 3.95Å; Y604-V609 HydrophobicContact CD2-CG1 4.08Å; Y604-V609 HydrophobicContact CE1-CG1 4.16Å; Y604-V609 HydrophobicContact CE1-CG2 4.48Å; Y604-V609 HydrophobicContact CE2-CG1 4.02Å; Y604-V609 HydrophobicContact CG-CG1 4.18Å; Y604-V609 HydrophobicContact CG-CG2 4.18Å; V609-V613 HydrophobicContact CG1-CB 4.13Å; V609-V613 HydrophobicContact CG1-CG1 3.99Å; V609-Q614 HydrophobicContact CB-CG 4.32Å; V609-Q614 HydrophobicContact CG1-CG 3.91Å; V609-Q614 PolarHBondContact O-NE2 3.08Å
610P96.9Very high96.3Very high22 Ų2260.7 Ų60.714%0.14330%0.302CS..  trans-59.1145.8179.7-25.735.7000112.7F597 H602 E612 V613 Q614F597-P610 HydrophobicContact CE1-CB 4.39Å; H602-P610 HydrophobicContact CB-CG 3.79Å; P610-E612 VanDerWaalsContact CB-OE2 3.28Å; P610-E612 WeakPolarHBondContact CB-OE2 3.41Å; P610-E612 PolarHBondContact O-N 3.28Å; P610-V613 HydrophobicContact CB-CG2 4.42Å; P610-V613 PolarHBondContact O-N 3.25Å; P610-V613 VanDerWaalsContact O-N 3.12Å; P610-Q614 PolarHBondContact O-N 2.91Å; P610-Q614 VanDerWaalsContact O-N 3.16Å
611V98.1Very high96.3Very high78 Ų7860.1 Ų60.147%0.47330%0.299SS..Hα-helixtrans-59.8-31.3-179.865.50000111.9Q614 K615V611-Q614 PolarHBondContact O-N 3.24Å; V611-K615 HydrophobicContact CG2-CD 4.3Å; V611-K615 HydrophobicContact CG2-CG 4.3Å; V611-K615 WeakPolarHBondContact O-CB 3.1Å; V611-K615 WeakPolarHBondContact O-CG 3.39Å; V611-K615 PolarHBondContact O-N 3.49Å
612E98.7Very high96.4Very high24 Ų2464.5 Ų64.511%0.11231%0.308CS..Hα-helixtrans-60.4-47.5176.5-64.483.9178.700111.4R569 Q572 F597 P610 K615 A616R569-E612 WeakPolarHBondContact CD-OE1 3.44Å; R569-E612 HydrophobicContact CG-CG 3.96Å; R569-E612 WeakPolarHBondContact CG-OE1 3.32Å; R569-E612 IonicContact CZ-OE1 2.69Å; R569-E612 IonicContact NE-OE1 2.8Å; R569-E612 IonicContact NH1-OE1 3.69Å; R569-E612 PolarHBondContact NH1-OE1 2.92Å; R569-E612 IonicContact NH1-OE2 3.74Å; R569-E612 PolarHBondContact NH1-OE2 3.4Å; R569-E612 VanDerWaalsContact NH1-OE2 3.13Å; Q572-E612 PolarHBondContact NE2-O 3.42Å; Q572-E612 VanDerWaalsContact OE1-CA 3.25Å; F597-E612 HydrophobicContact CE1-CB 3.8Å; F597-E612 HydrophobicContact CE1-CG 4.26Å; F597-E612 HydrophobicContact CE2-CB 4.29Å; F597-E612 HydrophobicContact CZ-CB 3.58Å; F597-E612 HydrophobicContact CZ-CG 3.88Å; P610-E612 VanDerWaalsContact CB-OE2 3.28Å; P610-E612 WeakPolarHBondContact CB-OE2 3.41Å; P610-E612 PolarHBondContact O-N 3.28Å; E612-K615 PolarHBondContact O-N 2.64Å; E612-A616 WeakPolarHBondContact O-CB 3.49Å; E612-A616 PolarHBondContact O-N 3.43Å
613V98.8Very high96.4Very high0 Ų064.1 Ų64.10%031%0.306CS..Hα-helixtrans-64-43.4177.4174.50000110.4L594 F597 H602 Y604 V609 P610 K615 A616 C617 V663L594-V613 HydrophobicContact CD2-CG1 4.18Å; F597-V613 HydrophobicContact CB-CG2 3.75Å; F597-V613 HydrophobicContact CD1-CG2 3.67Å; F597-V613 HydrophobicContact CE1-CG2 4.48Å; F597-V613 HydrophobicContact CG-CG2 3.81Å; H602-V613 HydrophobicContact CB-CG2 4.45Å; Y604-V613 HydrophobicContact CD2-CG1 4.19Å; Y604-V613 HydrophobicContact CE2-CG1 3.74Å; V609-V613 HydrophobicContact CG1-CB 4.13Å; V609-V613 HydrophobicContact CG1-CG1 3.99Å; P610-V613 HydrophobicContact CB-CG2 4.42Å; P610-V613 PolarHBondContact O-N 3.25Å; P610-V613 VanDerWaalsContact O-N 3.12Å; V613-K615 PolarHBondContact O-N 2.98Å; V613-A616 PolarHBondContact O-N 2.91Å; V613-C617 PolarHBondContact O-N 2.84Å; V613-C617 PolarHBondContact O-SG 2.94Å; V613-V663 HydrophobicContact CG1-CB 3.82Å; V613-V663 HydrophobicContact CG1-CG1 3.88Å; V613-V663 HydrophobicContact CG1-CG2 3.89Å; V613-V663 HydrophobicContact CG2-CG1 4.48Å
614Q98.7Very high96.5Very high79 Ų7964.4 Ų64.437%0.36931%0.306SS..Hα-helixtrans-62.2-43.2179-63.5179.340.400112.5Y604 V609 P610 V611 R618Y604-Q614 WeakPolarHBondContact OH-CA 3.25Å; V609-Q614 HydrophobicContact CB-CG 4.32Å; V609-Q614 HydrophobicContact CG1-CG 3.91Å; V609-Q614 PolarHBondContact O-NE2 3.08Å; P610-Q614 PolarHBondContact O-N 2.91Å; P610-Q614 VanDerWaalsContact O-N 3.16Å; V611-Q614 PolarHBondContact O-N 3.24Å; Q614-R618 WeakPolarHBondContact O-CB 3.13Å; Q614-R618 PolarHBondContact O-N 2.88Å
615K98.8Very high96.6Very high78 Ų7863.3 Ų63.334%0.33930%0.303SS..Hα-helixtrans-67.8-43.5178.6-73.2-179.4172.7-1690111.9T574 V611 E612 V613 R618 F619T574-K615 PolarHBondContact O-NZ 3.13Å; V611-K615 HydrophobicContact CG2-CD 4.3Å; V611-K615 HydrophobicContact CG2-CG 4.3Å; V611-K615 WeakPolarHBondContact O-CB 3.1Å; V611-K615 WeakPolarHBondContact O-CG 3.39Å; V611-K615 PolarHBondContact O-N 3.49Å; E612-K615 PolarHBondContact O-N 2.64Å; V613-K615 PolarHBondContact O-N 2.98Å; K615-R618 WeakPolarHBondContact O-CB 3.48Å; K615-R618 PolarHBondContact O-N 2.84Å; K615-F619 WeakPolarHBondContact O-CB 3.32Å; K615-F619 PolarHBondContact O-N 3.1Å
616A98.9Very high96.9Very high0 Ų061.6 Ų61.60%031%0.312CS..Hα-helixtrans-61.9-4417700000112.8G576 W578 T590 L594 E612 V613 R618 F619 L620G576-A616 WeakPolarHBondContact O-CA 3.35Å; G576-A616 WeakPolarHBondContact O-CB 3.2Å; W578-A616 HydrophobicContact CE3-CB 4.41Å; W578-A616 HydrophobicContact CH2-CB 4.43Å; W578-A616 HydrophobicContact CZ3-CB 3.61Å; T590-A616 HydrophobicContact CG2-CB 3.87Å; L594-A616 HydrophobicContact CD1-CB 4.38Å; L594-A616 HydrophobicContact CD2-CB 3.73Å; L594-A616 HydrophobicContact CG-CB 4.1Å; E612-A616 WeakPolarHBondContact O-CB 3.49Å; E612-A616 PolarHBondContact O-N 3.43Å; V613-A616 PolarHBondContact O-N 2.91Å; A616-R618 VanDerWaalsContact C-N 3.34Å; A616-R618 PolarHBondContact O-N 3.46Å; A616-F619 WeakPolarHBondContact O-CB 3.41Å; A616-F619 PolarHBondContact O-N 3.16Å; A616-L620 WeakPolarHBondContact O-CG 3.47Å; A616-L620 PolarHBondContact O-N 3.03Å
617C98.9Very high97.3Very high0 Ų063.1 Ų63.10%032%0.315CS..Hα-helixtrans-63.8-41.8176-64.80000111.6Y604 V613 L620 L621 L660 V663 H665Y604-C617 HydrophobicContact CE2-CB 4.48Å; V613-C617 PolarHBondContact O-N 2.84Å; V613-C617 PolarHBondContact O-SG 2.94Å; C617-L620 PolarHBondContact O-N 3.27Å; C617-L621 WeakPolarHBondContact O-CB 3.32Å; C617-L621 WeakPolarHBondContact O-CD1 3.33Å; C617-L621 VanDerWaalsContact O-CG 3.25Å; C617-L621 WeakPolarHBondContact O-CG 3.5Å; C617-L621 PolarHBondContact O-N 3.1Å; C617-L660 HydrophobicContact CB-CD2 3.83Å; C617-V663 VanDerWaalsContact SG-CG2 3.58Å; C617-H665 VanDerWaalsContact CB-CD2 3.46Å; C617-H665 WeakPolarHBondContact CB-CD2 3.4Å
618R98.8Very high98.1Very high136 Ų13653.2 Ų53.251%0.51327%0.269SS..Hα-helixtrans-59.8-48.4174.8-173.7-172.1-46.7177.95111.6Q614 K615 A616 L620 L621 E622Q614-R618 WeakPolarHBondContact O-CB 3.13Å; Q614-R618 PolarHBondContact O-N 2.88Å; K615-R618 WeakPolarHBondContact O-CB 3.48Å; K615-R618 PolarHBondContact O-N 2.84Å; A616-R618 VanDerWaalsContact C-N 3.34Å; A616-R618 PolarHBondContact O-N 3.46Å; R618-L620 VanDerWaalsContact C-N 3.3Å; R618-L620 PolarHBondContact O-N 3.26Å; R618-L621 PolarHBondContact O-N 2.96Å; R618-E622 WeakPolarHBondContact CD-OE1 3.31Å; R618-E622 HydrophobicContact CG-CG 4.22Å; R618-E622 VanDerWaalsContact CG-OE1 3.25Å; R618-E622 WeakPolarHBondContact CG-OE1 3.37Å; R618-E622 WeakPolarHBondContact O-CB 3.4Å; R618-E622 WeakPolarHBondContact O-CG 3.35Å; R618-E622 PolarHBondContact O-N 3.31Å
619F98.9Very high98.4Very high8 Ų845.3 Ų45.34%0.03523%0.232CC..Hα-helixtrans-53.4-48.6176.3174.1-91.8000111.2D575 F586 K615 A616 H623 Y642D575-F619 HydrophobicContact CB-CD2 4.39Å; F586-F619 HydrophobicContact CB-CE1 3.83Å; F586-F619 HydrophobicContact CB-CZ 3.83Å; F586-F619 HydrophobicContact CD1-CZ 4.44Å; F586-F619 HydrophobicContact CG-CZ 4.2Å; K615-F619 WeakPolarHBondContact O-CB 3.32Å; K615-F619 PolarHBondContact O-N 3.1Å; A616-F619 WeakPolarHBondContact O-CB 3.41Å; A616-F619 PolarHBondContact O-N 3.16Å; F619-H623 AromaticContact CD2-CE1 3.81Å; F619-H623 AromaticContact CE2-CE1 3.5Å; F619-H623 VanDerWaalsContact CE2-CE1 3.5Å; F619-H623 WeakPolarHBondContact CE2-CE1 3.34Å; F619-H623 AromaticContact CE2-ND1 3.99Å; F619-H623 AromaticContact CZ-CE1 3.92Å; F619-H623 PolarHBondContact O-N 3.48Å; F619-H623 PolarHBondContact O-ND1 2.93Å; F619-Y642 HydrophobicContact CE1-CD2 4.17Å; F619-Y642 AromaticContact CZ-CD2 3.78Å; F619-Y642 HydrophobicContact CZ-CD2 3.78Å; F619-Y642 HydrophobicContact CZ-CG 4.46Å
620L98.9Very high98.6Very high1 Ų143.8 Ų43.81%0.00522%0.223CC..Hα-helixtrans-61.7-50.8177.2-66.2175.6000111.2T587 T590 L594 A616 C617 R618 E622 H623 Q624 W630 A656 L660T587-L620 HydrophobicContact CG2-CD2 4.2Å; T590-L620 HydrophobicContact CG2-CD1 3.99Å; T590-L620 HydrophobicContact CG2-CD2 4.12Å; T590-L620 HydrophobicContact CG2-CG 3.97Å; L594-L620 HydrophobicContact CD1-CD1 3.72Å; A616-L620 WeakPolarHBondContact O-CG 3.47Å; A616-L620 PolarHBondContact O-N 3.03Å; C617-L620 PolarHBondContact O-N 3.27Å; R618-L620 VanDerWaalsContact C-N 3.3Å; R618-L620 PolarHBondContact O-N 3.26Å; L620-E622 VanDerWaalsContact C-N 3.31Å; L620-E622 PolarHBondContact O-N 3.48Å; L620-H623 CarbonylContact O-C 3.47Å; L620-H623 PolarHBondContact O-N 2.98Å; L620-Q624 PolarHBondContact O-N 3.28Å; L620-W630 PolarHBondContact O-NE1 3.16Å; L620-A656 HydrophobicContact CD1-CB 4.48Å; L620-A656 HydrophobicContact CD2-CB 4.1Å; L620-L660 HydrophobicContact CB-CD2 4.48Å; L620-L660 HydrophobicContact CD1-CD2 4.34Å; L620-L660 HydrophobicContact CD1-CG 4.09Å
621L98.9Very high98.7Very high41 Ų4142.8 Ų42.822%0.21522%0.216CC..Hα-helixtrans-63.1-34.2-176.7-68165.3000113.4C617 R618 H623 Q624 L660 H665 A670C617-L621 WeakPolarHBondContact O-CB 3.32Å; C617-L621 WeakPolarHBondContact O-CD1 3.33Å; C617-L621 VanDerWaalsContact O-CG 3.25Å; C617-L621 WeakPolarHBondContact O-CG 3.5Å; C617-L621 PolarHBondContact O-N 3.1Å; R618-L621 PolarHBondContact O-N 2.96Å; L621-H623 PolarHBondContact O-N 2.87Å; L621-Q624 PolarHBondContact O-N 3Å; L621-L660 HydrophobicContact CD2-CD1 4.08Å; L621-L660 HydrophobicContact CG-CD2 4.27Å; L621-H665 WeakPolarHBondContact CD1-CE1 3.48Å; L621-A670 HydrophobicContact CD2-CB 3.51Å
622E98.6Very high98.7Very high137 Ų13739.1 Ų39.164%0.6419%0.194SC*.Hα-helixtrans-65.6-22.8174.7-75.2174179.300112.9R618 L620R618-E622 WeakPolarHBondContact CD-OE1 3.31Å; R618-E622 HydrophobicContact CG-CG 4.22Å; R618-E622 VanDerWaalsContact CG-OE1 3.25Å; R618-E622 WeakPolarHBondContact CG-OE1 3.37Å; R618-E622 WeakPolarHBondContact O-CB 3.4Å; R618-E622 WeakPolarHBondContact O-CG 3.35Å; R618-E622 PolarHBondContact O-N 3.31Å; L620-E622 VanDerWaalsContact C-N 3.31Å; L620-E622 PolarHBondContact O-N 3.48Å
623H98.8Very high98.7Very high47 Ų4739.3 Ų39.322%0.21820%0.196CC..THydrogen-bonded Turntrans-1028177.7-65.683.7000113.3F619 L620 L621 M625 W630 Y642F619-H623 AromaticContact CD2-CE1 3.81Å; F619-H623 AromaticContact CE2-CE1 3.5Å; F619-H623 VanDerWaalsContact CE2-CE1 3.5Å; F619-H623 WeakPolarHBondContact CE2-CE1 3.34Å; F619-H623 AromaticContact CE2-ND1 3.99Å; F619-H623 AromaticContact CZ-CE1 3.92Å; F619-H623 PolarHBondContact O-N 3.48Å; F619-H623 PolarHBondContact O-ND1 2.93Å; L620-H623 CarbonylContact O-C 3.47Å; L620-H623 PolarHBondContact O-N 2.98Å; L621-H623 PolarHBondContact O-N 2.87Å; H623-M625 PolarHBondContact O-N 3.42Å; H623-W630 VanDerWaalsContact O-CD1 3.27Å; H623-Y642 HydrophobicContact CB-CE1 4.3Å; H623-Y642 HydrophobicContact CB-CE2 4.25Å; H623-Y642 AromaticContact CD2-CD1 3.38Å; H623-Y642 WeakPolarHBondContact CD2-CD1 3.49Å; H623-Y642 AromaticContact CD2-CD2 3.94Å; H623-Y642 AromaticContact CD2-CE1 3.62Å; H623-Y642 AromaticContact CD2-CG 3.56Å; H623-Y642 AromaticContact NE2-CD1 3.95Å; H623-Y642 AromaticContact NE2-CG 3.77Å
624Q98.9Very high98.7Very high29 Ų2939.4 Ų39.414%0.13620%0.196CC..  trans-68.9126.1172.8-165.7175.424.700109.9L620 L621 G628 W630 A670L620-Q624 PolarHBondContact O-N 3.28Å; L621-Q624 PolarHBondContact O-N 3Å; Q624-G628 PolarHBondContact NE2-O 3.26Å; Q624-W630 HydrophobicContact CB-CD2 4.47Å; Q624-W630 HydrophobicContact CB-CH2 3.96Å; Q624-W630 HydrophobicContact CB-CZ2 3.45Å; Q624-W630 VanDerWaalsContact CB-CZ2 3.45Å; Q624-W630 HydrophobicContact CG-CD2 4.31Å; Q624-W630 HydrophobicContact CG-CE3 4.24Å; Q624-W630 HydrophobicContact CG-CH2 3.5Å; Q624-W630 VanDerWaalsContact CG-CH2 3.5Å; Q624-W630 HydrophobicContact CG-CZ2 3.55Å; Q624-W630 HydrophobicContact CG-CZ3 3.85Å; Q624-W630 VanDerWaalsContact NE2-CH2 3.31Å; Q624-A670 PolarHBondContact NE2-O 2.64Å
625M98.8Very high98.7Very high36 Ų3636.7 Ų36.718%0.17718%0.183CC..  trans-75.2164.1179.5-59.9-179.873.400111.5H623 D627 G628 G629 Q644 A648H623-M625 PolarHBondContact O-N 3.42Å; M625-D627 WeakPolarHBondContact CB-OD1 3.46Å; M625-D627 PolarHBondContact O-N 3.32Å; M625-G628 PolarHBondContact O-N 2.95Å; M625-G629 WeakPolarHBondContact CB-O 3.46Å; M625-G629 PolarHBondContact N-O 3.45Å; M625-Q644 PolarHBondContact SD-NE2 2.81Å; M625-A648 WeakPolarHBondContact SD-CA 3.43Å; M625-A648 HydrophobicContact SD-CB 3.83Å; M625-A648 PolarHBondContact SD-N 2.93Å; M625-A648 VanDerWaalsContact SD-N 3.37Å
626S98.1Very high98.7Very high133 Ų13333 Ų3393%0.9317%0.167SC*.THydrogen-bonded Turntrans-64-24.3-178.455.80000114.2
627D97.7Very high98.7Very high71 Ų7133 Ų3338%0.3817%0.168SC..THydrogen-bonded Turntrans-81.5-2.2174.5651000112.9M625 G629 A648 L677M625-D627 WeakPolarHBondContact CB-OD1 3.46Å; M625-D627 PolarHBondContact O-N 3.32Å; D627-G629 PolarHBondContact OD1-N 2.95Å; D627-A648 WeakPolarHBondContact OD2-CB 3.31Å; D627-L677 HydrophobicContact CB-CD1 3.8Å; D627-L677 WeakPolarHBondContact O-CD1 3.27Å; D627-L677 WeakPolarHBondContact OD2-CD1 3.36Å
628G98.4Very high98.6Very high0 Ų035.1 Ų35.10%018%0.177CC..SBendtrans93.7-9-179.700000114.7Q624 M625 W630 G674Q624-G628 PolarHBondContact NE2-O 3.26Å; M625-G628 PolarHBondContact O-N 2.95Å; G628-W630 WeakPolarHBondContact O-CZ3 3.46Å; G628-G674 WeakPolarHBondContact O-CA 3.41Å; G628-G674 PolarHBondContact O-N 2.82Å
629G98.8Very high98.6Very high0 Ų032.9 Ų32.90%017%0.173CC..  trans-92.7-172.8-178.600000114.1M625 D627 T653M625-G629 WeakPolarHBondContact CB-O 3.46Å; M625-G629 PolarHBondContact N-O 3.45Å; D627-G629 PolarHBondContact OD1-N 2.95Å; G629-T653 WeakPolarHBondContact CA-OG1 3.15Å
630W98.9Very high98.6Very high0 Ų037.6 Ų37.60%019%0.191CC..  trans-129.9152.3171.6-76.6-97.9000109.3T587 L620 H623 Q624 G628 A648 Q649 N652 T653 A656 L657 L660T587-W630 HydrophobicContact CG2-CB 4.21Å; T587-W630 HydrophobicContact CG2-CG 4.41Å; L620-W630 PolarHBondContact O-NE1 3.16Å; H623-W630 VanDerWaalsContact O-CD1 3.27Å; Q624-W630 HydrophobicContact CB-CD2 4.47Å; Q624-W630 HydrophobicContact CB-CH2 3.96Å; Q624-W630 HydrophobicContact CB-CZ2 3.45Å; Q624-W630 VanDerWaalsContact CB-CZ2 3.45Å; Q624-W630 HydrophobicContact CG-CD2 4.31Å; Q624-W630 HydrophobicContact CG-CE3 4.24Å; Q624-W630 HydrophobicContact CG-CH2 3.5Å; Q624-W630 VanDerWaalsContact CG-CH2 3.5Å; Q624-W630 HydrophobicContact CG-CZ2 3.55Å; Q624-W630 HydrophobicContact CG-CZ3 3.85Å; Q624-W630 VanDerWaalsContact NE2-CH2 3.31Å; G628-W630 WeakPolarHBondContact O-CZ3 3.46Å; W630-A648 CarbonylContact O-C 3.6Å; W630-A648 WeakPolarHBondContact O-CA 3.46Å; W630-Q649 PolarHBondContact O-N 3.25Å; W630-Q649 VanDerWaalsContact O-O 3.12Å; W630-N652 HydrophobicContact CB-CB 4.07Å; W630-T653 HydrophobicContact CE3-CG2 4.22Å; W630-T653 PolarHBondContact N-OG1 3.22Å; W630-T653 PolarHBondContact O-OG1 2.74Å; W630-A656 HydrophobicContact CB-CB 4.44Å; W630-A656 HydrophobicContact CD2-CB 3.46Å; W630-A656 VanDerWaalsContact CD2-CB 3.46Å; W630-A656 HydrophobicContact CE3-CB 3.8Å; W630-A656 HydrophobicContact CG-CB 3.76Å; W630-A656 HydrophobicContact CH2-CB 4.44Å; W630-A656 HydrophobicContact CZ2-CB 4.15Å; W630-A656 HydrophobicContact CZ3-CB 4.28Å; W630-L657 HydrophobicContact CH2-CD2 4.46Å; W630-L657 HydrophobicContact CZ3-CD2 4.11Å; W630-L657 HydrophobicContact CZ3-CG 4.18Å; W630-L660 HydrophobicContact CH2-CD1 4.2Å; W630-L660 HydrophobicContact CZ2-CD1 4.26Å
631G98.8Very high98.6Very high0 Ų044.6 Ų44.60%022%0.217CC..  trans-158.7126.2-179.700000113.1Y642 Q644 S645G631-Y642 PolarHBondContact N-OH 3.38Å; G631-Y642 PolarHBondContact O-OH 2.79Å; G631-Q644 PolarHBondContact O-NE2 2.92Å; G631-Q644 VanDerWaalsContact O-NE2 3.09Å; G631-S645 VanDerWaalsContact CA-OG 3.23Å; G631-S645 WeakPolarHBondContact CA-OG 3.33Å; G631-S645 PolarHBondContact O-N 2.83Å; G631-S645 PolarHBondContact O-OG 3.03Å
632E98.8Very high98.6Very high2 Ų243.9 Ų43.91%0.00921%0.212CC..BIsolated β-bridgetrans-115.9136.8175.8-67.7179.1-104.400110.1V584 C585 F586 T587 Y642 V643 N652V584-E632 HydrophobicContact CG1-CB 4.3Å; C585-E632 WeakPolarHBondContact CB-OE2 3.28Å; C585-E632 PolarHBondContact N-OE1 3.09Å; C585-E632 PolarHBondContact N-OE2 3.12Å; F586-E632 WeakPolarHBondContact CD2-OE2 3.43Å; F586-E632 PolarHBondContact N-OE1 2.64Å; F586-E632 PolarHBondContact N-OE2 3.14Å; T587-E632 VanDerWaalsContact CB-OE1 3.29Å; T587-E632 WeakPolarHBondContact CB-OE1 3.17Å; T587-E632 WeakPolarHBondContact CG2-OE1 3.44Å; T587-E632 PolarHBondContact N-OE1 2.95Å; T587-E632 PolarHBondContact OG1-OE1 3.3Å; E632-Y642 HydrophobicContact CG-CD1 4.3Å; E632-Y642 HydrophobicContact CG-CD2 3.89Å; E632-Y642 HydrophobicContact CG-CE1 3.8Å; E632-Y642 HydrophobicContact CG-CE2 3.33Å; E632-Y642 HydrophobicContact CG-CG 4.34Å; E632-V643 WeakPolarHBondContact CA-O 3.29Å; E632-N652 PolarHBondContact N-OD1 2.74Å
633D98.8Very high98.6Very high27 Ų2738.7 Ų38.714%0.14419%0.189CC..  trans-80.5151.2165.4-92.65.8000109.5R10 E635 S636 V643 S645R10-D633 IonicContact CZ-OD1 3.23Å; R10-D633 IonicContact CZ-OD2 3.79Å; R10-D633 IonicContact NE-OD1 3.95Å; R10-D633 IonicContact NE-OD2 3.93Å; R10-D633 IonicContact NH2-OD2 3.75Å; R10-D633 PolarHBondContact NH2-OD2 3.07Å; D633-E635 PolarHBondContact O-N 3.08Å; D633-E635 VanDerWaalsContact O-N 3.1Å; D633-S636 VanDerWaalsContact O-CB 3.24Å; D633-S636 WeakPolarHBondContact O-CB 3.29Å; D633-S636 PolarHBondContact O-N 3.16Å; D633-S636 PolarHBondContact O-OG 3.41Å; D633-V643 HydrophobicContact CB-CB 4.49Å; D633-V643 HydrophobicContact CB-CG1 4.11Å; D633-V643 PolarHBondContact N-O 2.97Å; D633-S645 WeakPolarHBondContact OD1-CA 3.39Å; D633-S645 WeakPolarHBondContact OD1-CB 3.41Å
634F98.8Very high98.6Very high3 Ų340.3 Ų40.31%0.01320%0.197CC..THydrogen-bonded Turntrans-51.6-35.5179.3179.3-98.7000113.2H145 V584 S636 C637 E638 I693 V696 A702H145-F634 AromaticContact CE1-CD1 3.63Å; H145-F634 AromaticContact CE1-CE1 3.54Å; H145-F634 AromaticContact NE2-CD1 3.81Å; H145-F634 AromaticContact NE2-CE1 3.27Å; H145-F634 VanDerWaalsContact NE2-CE1 3.27Å; H145-F634 WeakPolarHBondContact NE2-CE1 3.48Å; H145-F634 AromaticContact NE2-CZ 3.83Å; V584-F634 HydrophobicContact CG2-CD2 3.86Å; V584-F634 HydrophobicContact CG2-CE2 4.38Å; F634-S636 PolarHBondContact O-N 2.84Å; F634-C637 WeakPolarHBondContact O-CB 3.37Å; F634-C637 PolarHBondContact O-N 2.95Å; F634-E638 HydrophobicContact CD1-CG 4.31Å; F634-E638 HydrophobicContact CE1-CG 3.94Å; F634-I693 HydrophobicContact CD2-CG2 4.19Å; F634-V696 HydrophobicContact CE2-CB 3.92Å; F634-V696 HydrophobicContact CE2-CG2 3.69Å; F634-V696 HydrophobicContact CZ-CG2 3.98Å; F634-A702 HydrophobicContact CD2-CB 3.65Å; F634-A702 VanDerWaalsContact CE2-CA 3.47Å; F634-A702 HydrophobicContact CE2-CB 3.4Å; F634-A702 HydrophobicContact CG-CB 4.37Å; F634-A702 HydrophobicContact CZ-CB 3.92Å
635E98.6Very high98.6Very high21 Ų2139.1 Ų39.110%0.09819%0.192CC..Hα-helixtrans-56.2-15.6176.3-72.688.8151.800113.8R8 R10 D633 C637 E638 Q639 V643R8-E635 IonicContact CZ-OE1 3.42Å; R8-E635 IonicContact NE-OE1 3.78Å; R8-E635 PolarHBondContact NE-OE1 3.36Å; R8-E635 IonicContact NH2-OE1 3.39Å; R8-E635 PolarHBondContact NH2-OE1 3.29Å; R10-E635 IonicContact CZ-OE1 3.32Å; R10-E635 IonicContact CZ-OE2 2.68Å; R10-E635 VanDerWaalsContact CZ-OE2 3.24Å; R10-E635 IonicContact NH1-OE1 2.64Å; R10-E635 IonicContact NH1-OE2 2.89Å; R10-E635 PolarHBondContact NH1-OE2 2.85Å; R10-E635 IonicContact NH2-OE1 3.59Å; R10-E635 PolarHBondContact NH2-OE1 2.89Å; R10-E635 IonicContact NH2-OE2 3.31Å; R10-E635 PolarHBondContact NH2-OE2 3.16Å; D633-E635 PolarHBondContact O-N 3.08Å; D633-E635 VanDerWaalsContact O-N 3.1Å; E635-C637 PolarHBondContact O-N 3.37Å; E635-E638 WeakPolarHBondContact CG-OE2 3.35Å; E635-E638 PolarHBondContact O-N 2.9Å; E635-Q639 VanDerWaalsContact O-CB 3.3Å; E635-Q639 WeakPolarHBondContact O-CB 3.49Å; E635-Q639 WeakPolarHBondContact O-CG 3.33Å; E635-Q639 PolarHBondContact O-N 3Å; E635-V643 HydrophobicContact CB-CG2 4.41Å
636S98.8Very high98.5Very high0 Ų041.4 Ų41.40%022%0.224CC..Hα-helixtrans-57.3-36170.3-55.40000112.1D633 F634 R640 R641 V643D633-S636 VanDerWaalsContact O-CB 3.24Å; D633-S636 WeakPolarHBondContact O-CB 3.29Å; D633-S636 PolarHBondContact O-N 3.16Å; D633-S636 PolarHBondContact O-OG 3.41Å; F634-S636 PolarHBondContact O-N 2.84Å; S636-R640 VanDerWaalsContact O-CA 3.26Å; S636-R640 WeakPolarHBondContact O-CA 3.37Å; S636-R640 PolarHBondContact O-N 3.5Å; S636-R641 WeakPolarHBondContact CA-O 3.03Å; S636-R641 WeakPolarHBondContact CB-O 3.48Å; S636-R641 PolarHBondContact O-N 3.13Å; S636-V643 WeakPolarHBondContact OG-CB 3.49Å; S636-V643 PolarHBondContact OG-N 3.42Å; S636-V643 PolarHBondContact OG-O 3.15Å
637C98.8Very high98.5Very high1 Ų137.6 Ų37.61%0.00720%0.201CC..Hα-helixtrans-71.8-47.7175.7-57.10000111.4F634 E635 R640 V696 K699F634-C637 WeakPolarHBondContact O-CB 3.37Å; F634-C637 PolarHBondContact O-N 2.95Å; E635-C637 PolarHBondContact O-N 3.37Å; C637-R640 WeakPolarHBondContact O-CG 3.38Å; C637-R640 PolarHBondContact O-N 3.2Å; C637-V696 HydrophobicContact CB-CG2 3.92Å; C637-K699 CarbonylContact C-O 3.56Å; C637-K699 WeakPolarHBondContact CB-O 3.49Å
638E97.9Very high98.5Very high44 Ų4434.2 Ų34.221%0.20618%0.183CC..Hα-helixtrans-62.4-47.2-179.1-63.2178.3158.900111.5Y287 F634 E635Y287-E638 HydrophobicContact CE2-CB 4.11Å; Y287-E638 PolarHBondContact OH-O 3.07Å; F634-E638 HydrophobicContact CD1-CG 4.31Å; F634-E638 HydrophobicContact CE1-CG 3.94Å; E635-E638 WeakPolarHBondContact CG-OE2 3.35Å; E635-E638 PolarHBondContact O-N 2.9Å
639Q98.6Very high98.6Very high90 Ų9034.6 Ų34.642%0.42118%0.184SC..Hα-helixtrans-86.9-7.9-176.5-59.9-178.136.100113.2E635 R641E635-Q639 VanDerWaalsContact O-CB 3.3Å; E635-Q639 WeakPolarHBondContact O-CB 3.49Å; E635-Q639 WeakPolarHBondContact O-CG 3.33Å; E635-Q639 PolarHBondContact O-N 3Å; Q639-R641 HydrophobicContact CB-CG 4.03Å; Q639-R641 PolarHBondContact O-N 3.24Å
640R98.4Very high98.6Very high107 Ų10734.7 Ų34.740%0.40419%0.185SC..THydrogen-bonded Turntrans54.438.2178.7-50.3-173.265.8175.1-0.4113.1R573 E579 S636 C637R573-R640 PolarHBondContact NH1-O 3.12Å; R573-R640 PolarHBondContact NH2-O 2.88Å; E579-R640 WeakPolarHBondContact OE1-CG 3.46Å; E579-R640 IonicContact OE1-CZ 2.76Å; E579-R640 IonicContact OE1-NE 3.77Å; E579-R640 PolarHBondContact OE1-NE 3.35Å; E579-R640 IonicContact OE1-NH2 3.36Å; E579-R640 PolarHBondContact OE1-NH2 2.87Å; E579-R640 IonicContact OE2-CZ 3.68Å; E579-R640 IonicContact OE2-NE 3.84Å; E579-R640 PolarHBondContact OE2-NE 2.88Å; E579-R640 IonicContact OE2-NH2 3.99Å; E579-R640 PolarHBondContact OE2-NH2 3.27Å; S636-R640 VanDerWaalsContact O-CA 3.26Å; S636-R640 WeakPolarHBondContact O-CA 3.37Å; S636-R640 PolarHBondContact O-N 3.5Å; C637-R640 WeakPolarHBondContact O-CG 3.38Å; C637-R640 PolarHBondContact O-N 3.2Å
641R98.7Very high98.6Very high147 Ų14735.2 Ų35.256%0.55519%0.187SC*.SBendtrans-151.3157.1175.667.3-176.7-176.7116.8-0109.5F586 S636 Q639 V643F586-R641 VanDerWaalsContact CE2-CA 3.42Å; F586-R641 WeakPolarHBondContact CE2-O 3.44Å; S636-R641 WeakPolarHBondContact CA-O 3.03Å; S636-R641 WeakPolarHBondContact CB-O 3.48Å; S636-R641 PolarHBondContact O-N 3.13Å; Q639-R641 HydrophobicContact CB-CG 4.03Å; Q639-R641 PolarHBondContact O-N 3.24Å; R641-V643 HydrophobicContact CG-CG2 4.39Å; R641-V643 PolarHBondContact O-N 3.09Å; R641-V643 VanDerWaalsContact O-N 3.14Å
642Y98.8Very high98.6Very high27 Ų2735.2 Ų35.211%0.10619%0.187CC..  trans-61.9118.1178.1-158.2-77.8000110.2F586 T587 F619 H623 G631 E632 Q644F586-Y642 HydrophobicContact CB-CD2 3.9Å; F586-Y642 HydrophobicContact CB-CE2 4.48Å; F586-Y642 HydrophobicContact CD2-CD2 4.32Å; F586-Y642 HydrophobicContact CG-CD2 4.4Å; T587-Y642 HydrophobicContact CG2-CE2 4.18Å; F619-Y642 HydrophobicContact CE1-CD2 4.17Å; F619-Y642 AromaticContact CZ-CD2 3.78Å; F619-Y642 HydrophobicContact CZ-CD2 3.78Å; F619-Y642 HydrophobicContact CZ-CG 4.46Å; H623-Y642 HydrophobicContact CB-CE1 4.3Å; H623-Y642 HydrophobicContact CB-CE2 4.25Å; H623-Y642 AromaticContact CD2-CD1 3.38Å; H623-Y642 WeakPolarHBondContact CD2-CD1 3.49Å; H623-Y642 AromaticContact CD2-CD2 3.94Å; H623-Y642 AromaticContact CD2-CE1 3.62Å; H623-Y642 AromaticContact CD2-CG 3.56Å; H623-Y642 AromaticContact NE2-CD1 3.95Å; H623-Y642 AromaticContact NE2-CG 3.77Å; G631-Y642 PolarHBondContact N-OH 3.38Å; G631-Y642 PolarHBondContact O-OH 2.79Å; E632-Y642 HydrophobicContact CG-CD1 4.3Å; E632-Y642 HydrophobicContact CG-CD2 3.89Å; E632-Y642 HydrophobicContact CG-CE1 3.8Å; E632-Y642 HydrophobicContact CG-CE2 3.33Å; E632-Y642 HydrophobicContact CG-CG 4.34Å; Y642-Q644 HydrophobicContact CE1-CB 4.37Å
643V98.8Very high98.6Very high27 Ų2735.1 Ų35.116%0.16419%0.187CC..  trans-110.6102.4171.8-178.50000107.1E632 D633 E635 S636 R641 S645E632-V643 WeakPolarHBondContact CA-O 3.29Å; D633-V643 HydrophobicContact CB-CB 4.49Å; D633-V643 HydrophobicContact CB-CG1 4.11Å; D633-V643 PolarHBondContact N-O 2.97Å; E635-V643 HydrophobicContact CB-CG2 4.41Å; S636-V643 WeakPolarHBondContact OG-CB 3.49Å; S636-V643 PolarHBondContact OG-N 3.42Å; S636-V643 PolarHBondContact OG-O 3.15Å; R641-V643 HydrophobicContact CG-CG2 4.39Å; R641-V643 PolarHBondContact O-N 3.09Å; R641-V643 VanDerWaalsContact O-N 3.14Å; V643-S645 PolarHBondContact O-N 2.7Å
644Q98.7Very high98.6Very high82 Ų8233.8 Ų33.838%0.38318%0.18SC..BIsolated β-bridgetrans-58.2123.9-179.4179.760.761.100110.7M625 G631 Y642M625-Q644 PolarHBondContact SD-NE2 2.81Å; G631-Q644 PolarHBondContact O-NE2 2.92Å; G631-Q644 VanDerWaalsContact O-NE2 3.09Å; Y642-Q644 HydrophobicContact CE1-CB 4.37Å
645S98.4Very high98.6Very high4 Ų433.7 Ų33.73%0.02818%0.179CC..  trans-76.7164.4174.267.70000111.6G631 D633 V643 A647G631-S645 VanDerWaalsContact CA-OG 3.23Å; G631-S645 WeakPolarHBondContact CA-OG 3.33Å; G631-S645 PolarHBondContact O-N 2.83Å; G631-S645 PolarHBondContact O-OG 3.03Å; D633-S645 WeakPolarHBondContact OD1-CA 3.39Å; D633-S645 WeakPolarHBondContact OD1-CB 3.41Å; V643-S645 PolarHBondContact O-N 2.7Å; S645-A647 PolarHBondContact O-N 3.09Å; S645-A647 PolarHBondContact OG-O 3.13Å
646G97.3Very high98.6Very high84 Ų8432.7 Ų32.787%0.86618%0.175SC*.SBendtrans-69.1-15.9179.400000115.2
647A97.9Very high98.6Very high52 Ų5232.7 Ų32.743%0.4318%0.175SC..SBendtrans-151.3150179.200000110.3S645 Q649S645-A647 PolarHBondContact O-N 3.09Å; S645-A647 PolarHBondContact OG-O 3.13Å; A647-Q649 PolarHBondContact O-N 2.82Å; A647-Q649 PolarHBondContact O-NE2 2.98Å
648A98.5Very high98.6Very high0 Ų032.6 Ų32.60%017%0.174CC..  trans-55.5140.2174.900000110.9M625 D627 W630 L677 K681M625-A648 WeakPolarHBondContact SD-CA 3.43Å; M625-A648 HydrophobicContact SD-CB 3.83Å; M625-A648 PolarHBondContact SD-N 2.93Å; M625-A648 VanDerWaalsContact SD-N 3.37Å; D627-A648 WeakPolarHBondContact OD2-CB 3.31Å; W630-A648 CarbonylContact O-C 3.6Å; W630-A648 WeakPolarHBondContact O-CA 3.46Å; A648-L677 HydrophobicContact CB-CD1 3.93Å; A648-L677 HydrophobicContact CB-CD2 4.39Å; A648-K681 PolarHBondContact O-NZ 3.19Å
649Q98.9Very high98.7Very high8 Ų830.5 Ų30.54%0.03716%0.164CC..  trans-108.5138.6176.2-52.9-62.4-64.300109.5W630 A647 H651 N652 T653 E691 N692W630-Q649 PolarHBondContact O-N 3.25Å; W630-Q649 VanDerWaalsContact O-O 3.12Å; A647-Q649 PolarHBondContact O-N 2.82Å; A647-Q649 PolarHBondContact O-NE2 2.98Å; Q649-H651 PolarHBondContact O-N 3.3Å; Q649-N652 HydrophobicContact CB-CB 4.24Å; Q649-N652 VanDerWaalsContact CB-OD1 3.26Å; Q649-N652 WeakPolarHBondContact CB-OD1 3.41Å; Q649-N652 WeakPolarHBondContact CG-OD1 3.45Å; Q649-N652 PolarHBondContact O-N 3.11Å; Q649-T653 VanDerWaalsContact O-CB 3.29Å; Q649-T653 WeakPolarHBondContact O-CB 3.25Å; Q649-T653 PolarHBondContact O-N 2.72Å; Q649-T653 PolarHBondContact O-OG1 3.06Å; Q649-E691 VanDerWaalsContact CA-OE2 3.24Å; Q649-E691 WeakPolarHBondContact CA-OE2 3.45Å; Q649-E691 VanDerWaalsContact OE1-CB 3.27Å; Q649-N692 VanDerWaalsContact OE1-CB 3.26Å
650I98.9Very high98.7Very high2 Ų226.2 Ų26.21%0.0114%0.144CC..Hα-helixtrans-58.6-47.6-176.6-74169.1000110.5T653 C654 L678 K681 W688 P689 E691 P713I650-T653 PolarHBondContact O-N 2.79Å; I650-C654 WeakPolarHBondContact O-CB 3.31Å; I650-C654 PolarHBondContact O-N 3.32Å; I650-C654 PolarHBondContact O-SG 3.4Å; I650-L678 HydrophobicContact CG1-CD2 4.49Å; I650-L678 HydrophobicContact CG2-CD2 4.17Å; I650-K681 HydrophobicContact CD1-CB 4.49Å; I650-K681 HydrophobicContact CD1-CD 4.17Å; I650-K681 HydrophobicContact CG1-CD 3.83Å; I650-W688 HydrophobicContact CD1-CB 3.86Å; I650-W688 HydrophobicContact CD1-CG 4.17Å; I650-P689 HydrophobicContact CD1-CG 4.08Å; I650-E691 WeakPolarHBondContact CB-OE2 3.3Å; I650-E691 WeakPolarHBondContact CG1-OE2 3.41Å; I650-E691 PolarHBondContact N-OE2 2.89Å; I650-P713 HydrophobicContact CG2-CG 3.36Å
651H98.9Very high98.7Very high11 Ų1121.1 Ų21.15%0.05113%0.125CC..Hα-helixtrans-65.8-46.2-177.753.1-88.9000111.8Q649 T653 C654 W655 N692Q649-H651 PolarHBondContact O-N 3.3Å; H651-T653 VanDerWaalsContact C-N 3.35Å; H651-T653 PolarHBondContact O-N 3.08Å; H651-C654 PolarHBondContact O-N 3.49Å; H651-W655 HydrophobicContact CB-CH2 3.95Å; H651-W655 HydrophobicContact CB-CZ2 3.9Å; H651-W655 HydrophobicContact CB-CZ3 4.29Å; H651-W655 AromaticContact CD2-CH2 3.69Å; H651-W655 AromaticContact CD2-CZ3 3.56Å; H651-W655 PolarHBondContact O-N 3.28Å; H651-N692 PolarHBondContact CE1-O 3.44Å
652N98.9Very high98.7Very high0 Ų014.4 Ų14.40%010%0.101CC..Hα-helixtrans-62.2-42.4176.4-60.3133.3000112V584 T587 W630 E632 Q649 W655 A656V584-N652 PolarHBondContact O-ND2 3.25Å; T587-N652 HydrophobicContact CG2-CB 4.17Å; T587-N652 PolarHBondContact OG1-ND2 2.69Å; W630-N652 HydrophobicContact CB-CB 4.07Å; E632-N652 PolarHBondContact N-OD1 2.74Å; Q649-N652 HydrophobicContact CB-CB 4.24Å; Q649-N652 VanDerWaalsContact CB-OD1 3.26Å; Q649-N652 WeakPolarHBondContact CB-OD1 3.41Å; Q649-N652 WeakPolarHBondContact CG-OD1 3.45Å; Q649-N652 PolarHBondContact O-N 3.11Å; N652-W655 PolarHBondContact O-N 3Å; N652-A656 WeakPolarHBondContact O-CB 3.3Å; N652-A656 PolarHBondContact O-N 2.93Å
653T98.9Very high98.7Very high0 Ų013.1 Ų13.10%010%0.096CC..Hα-helixtrans-60-47.5176.5-59.70000110.8G629 W630 Q649 I650 H651 L657 L677 L678G629-T653 WeakPolarHBondContact CA-OG1 3.15Å; W630-T653 HydrophobicContact CE3-CG2 4.22Å; W630-T653 PolarHBondContact N-OG1 3.22Å; W630-T653 PolarHBondContact O-OG1 2.74Å; Q649-T653 VanDerWaalsContact O-CB 3.29Å; Q649-T653 WeakPolarHBondContact O-CB 3.25Å; Q649-T653 PolarHBondContact O-N 2.72Å; Q649-T653 PolarHBondContact O-OG1 3.06Å; I650-T653 PolarHBondContact O-N 2.79Å; H651-T653 VanDerWaalsContact C-N 3.35Å; H651-T653 PolarHBondContact O-N 3.08Å; T653-L657 HydrophobicContact CG2-CD1 3.78Å; T653-L657 HydrophobicContact CG2-CG 4.47Å; T653-L657 WeakPolarHBondContact O-CB 3.34Å; T653-L657 WeakPolarHBondContact O-CD1 3.24Å; T653-L657 WeakPolarHBondContact O-CG 3.43Å; T653-L657 PolarHBondContact O-N 3.48Å; T653-L677 HydrophobicContact CG2-CD2 4.17Å; T653-L678 HydrophobicContact CG2-CD1 4.47Å; T653-L678 HydrophobicContact CG2-CD2 4.03Å; T653-L678 HydrophobicContact CG2-CG 4.09Å
654C99Very high98.7Very high0 Ų016 Ų160%010%0.104CC..Hα-helixtrans-61.6-46.9177.7-67.70000112.1I650 H651 A656 L657 L658 F712 T716I650-C654 WeakPolarHBondContact O-CB 3.31Å; I650-C654 PolarHBondContact O-N 3.32Å; I650-C654 PolarHBondContact O-SG 3.4Å; H651-C654 PolarHBondContact O-N 3.49Å; C654-A656 PolarHBondContact O-N 3.26Å; C654-L657 PolarHBondContact O-N 3.06Å; C654-L658 WeakPolarHBondContact O-CB 3.38Å; C654-L658 VanDerWaalsContact O-CG 3.23Å; C654-L658 WeakPolarHBondContact O-CG 3.27Å; C654-L658 PolarHBondContact O-N 2.94Å; C654-F712 HydrophobicContact CB-CB 3.6Å; C654-F712 HydrophobicContact CB-CG 4.42Å; C654-T716 VanDerWaalsContact CB-OG1 3.25Å; C654-T716 WeakPolarHBondContact CB-OG1 3.43Å
655W99Very high98.7Very high0 Ų013 Ų130%09%0.09CC..Hα-helixtrans-63.1-43.6-179.3-60.3-32.5000112.5V584 Y588 W591 H651 N652 L657 L658 G659 Y708 F712V584-W655 WeakPolarHBondContact O-CZ3 3.47Å; Y588-W655 AromaticContact CD2-CD2 3.82Å; Y588-W655 HydrophobicContact CD2-CD2 3.82Å; Y588-W655 AromaticContact CD2-CE2 3.59Å; Y588-W655 HydrophobicContact CD2-CE3 4Å; Y588-W655 HydrophobicContact CD2-CG 4.5Å; Y588-W655 AromaticContact CD2-CH2 3.74Å; Y588-W655 HydrophobicContact CD2-CH2 3.74Å; Y588-W655 AromaticContact CD2-CZ2 3.55Å; Y588-W655 HydrophobicContact CD2-CZ2 3.55Å; Y588-W655 AromaticContact CD2-CZ3 3.96Å; Y588-W655 HydrophobicContact CD2-CZ3 3.96Å; Y588-W655 HydrophobicContact CE2-CH2 4.48Å; Y588-W655 HydrophobicContact CE2-CZ2 4.05Å; Y588-W655 HydrophobicContact CG-CE3 4.33Å; Y588-W655 HydrophobicContact CG-CH2 4.35Å; Y588-W655 HydrophobicContact CG-CZ3 4.24Å; W591-W655 HydrophobicContact CB-CB 3.93Å; W591-W655 WeakPolarHBondContact CB-O 3.46Å; W591-W655 HydrophobicContact CD2-CG 4.49Å; W591-W655 HydrophobicContact CE3-CB 4.4Å; W591-W655 AromaticContact CE3-CD1 3.4Å; W591-W655 VanDerWaalsContact CE3-CD1 3.4Å; W591-W655 AromaticContact CE3-CG 3.96Å; W591-W655 HydrophobicContact CE3-CG 3.96Å; W591-W655 AromaticContact CE3-NE1 3.93Å; W591-W655 HydrophobicContact CG-CB 4.33Å; W591-W655 AromaticContact CZ3-CD1 3.76Å; W591-W655 AromaticContact CZ3-NE1 3.88Å; H651-W655 HydrophobicContact CB-CH2 3.95Å; H651-W655 HydrophobicContact CB-CZ2 3.9Å; H651-W655 HydrophobicContact CB-CZ3 4.29Å; H651-W655 AromaticContact CD2-CH2 3.69Å; H651-W655 AromaticContact CD2-CZ3 3.56Å; H651-W655 PolarHBondContact O-N 3.28Å; N652-W655 PolarHBondContact O-N 3Å; W655-L657 PolarHBondContact O-N 3.36Å; W655-L658 PolarHBondContact O-N 3.41Å; W655-G659 PolarHBondContact O-N 2.91Å; W655-Y708 HydrophobicContact CH2-CD2 4.33Å; W655-Y708 HydrophobicContact CH2-CE2 4.36Å; W655-Y708 AromaticContact CZ2-CD2 3.7Å; W655-Y708 HydrophobicContact CZ2-CD2 3.7Å; W655-Y708 AromaticContact CZ2-CE2 3.75Å; W655-Y708 HydrophobicContact CZ2-CE2 3.75Å; W655-F712 AromaticContact CD1-CD1 3.82Å; W655-F712 AromaticContact CD1-CE1 3.71Å; W655-F712 AromaticContact CE2-CE2 3.98Å; W655-F712 HydrophobicContact CZ2-CD2 4.48Å; W655-F712 HydrophobicContact CZ2-CE2 4.05Å; W655-F712 AromaticContact NE1-CD1 3.57Å; W655-F712 AromaticContact NE1-CD2 3.57Å; W655-F712 AromaticContact NE1-CE1 3.31Å; W655-F712 VanDerWaalsContact NE1-CE1 3.31Å; W655-F712 AromaticContact NE1-CE2 3.28Å; W655-F712 VanDerWaalsContact NE1-CE2 3.28Å; W655-F712 AromaticContact NE1-CG 3.71Å; W655-F712 AromaticContact NE1-CZ 3.17Å
656A99Very high98.7Very high0 Ų017.3 Ų17.30%012%0.118CC..Hα-helixtrans-58.7-47.3174.500000111.6T587 L620 W630 N652 C654 G659 L660T587-A656 HydrophobicContact CG2-CB 4.31Å; L620-A656 HydrophobicContact CD1-CB 4.48Å; L620-A656 HydrophobicContact CD2-CB 4.1Å; W630-A656 HydrophobicContact CB-CB 4.44Å; W630-A656 HydrophobicContact CD2-CB 3.46Å; W630-A656 VanDerWaalsContact CD2-CB 3.46Å; W630-A656 HydrophobicContact CE3-CB 3.8Å; W630-A656 HydrophobicContact CG-CB 3.76Å; W630-A656 HydrophobicContact CH2-CB 4.44Å; W630-A656 HydrophobicContact CZ2-CB 4.15Å; W630-A656 HydrophobicContact CZ3-CB 4.28Å; N652-A656 WeakPolarHBondContact O-CB 3.3Å; N652-A656 PolarHBondContact O-N 2.93Å; C654-A656 PolarHBondContact O-N 3.26Å; A656-G659 PolarHBondContact O-N 3.18Å; A656-L660 WeakPolarHBondContact O-CB 3.18Å; A656-L660 VanDerWaalsContact O-CG 3.29Å; A656-L660 WeakPolarHBondContact O-CG 3.46Å; A656-L660 PolarHBondContact O-N 3.46Å
657L98.9Very high98.7Very high0 Ų016.1 Ų16.10%09%0.092CC..Hα-helixtrans-65.3-44.8178.7-70.4170.5000112.6W630 T653 C654 W655 G659 L660 M661 I671 V675 L678 T716W630-L657 HydrophobicContact CH2-CD2 4.46Å; W630-L657 HydrophobicContact CZ3-CD2 4.11Å; W630-L657 HydrophobicContact CZ3-CG 4.18Å; T653-L657 HydrophobicContact CG2-CD1 3.78Å; T653-L657 HydrophobicContact CG2-CG 4.47Å; T653-L657 WeakPolarHBondContact O-CB 3.34Å; T653-L657 WeakPolarHBondContact O-CD1 3.24Å; T653-L657 WeakPolarHBondContact O-CG 3.43Å; T653-L657 PolarHBondContact O-N 3.48Å; C654-L657 PolarHBondContact O-N 3.06Å; W655-L657 PolarHBondContact O-N 3.36Å; L657-G659 VanDerWaalsContact C-N 3.31Å; L657-G659 PolarHBondContact O-N 2.86Å; L657-L660 PolarHBondContact O-N 3.35Å; L657-M661 HydrophobicContact CB-CE 4.16Å; L657-M661 VanDerWaalsContact O-CB 3.24Å; L657-M661 WeakPolarHBondContact O-CB 3.45Å; L657-M661 WeakPolarHBondContact O-CE 3.23Å; L657-M661 VanDerWaalsContact O-CG 3.28Å; L657-M661 WeakPolarHBondContact O-CG 3.42Å; L657-M661 PolarHBondContact O-N 3.2Å; L657-I671 HydrophobicContact CD2-CB 4.28Å; L657-I671 HydrophobicContact CD2-CG2 4.07Å; L657-I671 WeakPolarHBondContact CD2-O 3.3Å; L657-V675 HydrophobicContact CD1-CG2 4.32Å; L657-L678 HydrophobicContact CD1-CD1 3.94Å; L657-T716 HydrophobicContact CB-CG2 3.57Å; L657-T716 HydrophobicContact CD1-CG2 3.71Å; L657-T716 HydrophobicContact CG-CG2 4.31Å
658L98.9Very high98.6Very high0 Ų016.9 Ų16.90%09%0.086CC..Hα-helixtrans-59.1-44.2177.1-74.4169000110.8W591 C654 W655 A662 F712 W715 T716 R719W591-L658 HydrophobicContact CG-CB 4.33Å; W591-L658 HydrophobicContact CZ2-CD1 4.13Å; C654-L658 WeakPolarHBondContact O-CB 3.38Å; C654-L658 VanDerWaalsContact O-CG 3.23Å; C654-L658 WeakPolarHBondContact O-CG 3.27Å; C654-L658 PolarHBondContact O-N 2.94Å; W655-L658 PolarHBondContact O-N 3.41Å; L658-A662 VanDerWaalsContact O-CB 3.27Å; L658-A662 WeakPolarHBondContact O-CB 3.49Å; L658-A662 PolarHBondContact O-N 3.32Å; L658-F712 HydrophobicContact CD1-CD1 3.8Å; L658-F712 HydrophobicContact CD1-CE1 4.25Å; L658-W715 HydrophobicContact CD2-CG 4.14Å; L658-T716 WeakPolarHBondContact CG-OG1 3.33Å; L658-R719 HydrophobicContact CD2-CB 4.45Å; L658-R719 PolarHBondContact O-NH1 2.97Å; L658-R719 VanDerWaalsContact O-NH1 3.08Å
659G98.9Very high98.6Very high0 Ų023.5 Ų23.50%012%0.117CC..Hα-helixtrans-63.1-51.8176.200000112.9W655 A656 L657 M661 A662 V663W655-G659 PolarHBondContact O-N 2.91Å; A656-G659 PolarHBondContact O-N 3.18Å; L657-G659 VanDerWaalsContact C-N 3.31Å; L657-G659 PolarHBondContact O-N 2.86Å; G659-M661 VanDerWaalsContact C-N 3.3Å; G659-M661 PolarHBondContact O-N 3.45Å; G659-A662 WeakPolarHBondContact O-CB 3.36Å; G659-A662 PolarHBondContact O-N 3.03Å; G659-V663 PolarHBondContact O-N 2.94Å
660L98.9Very high98.6Very high0 Ų023.1 Ų23.10%012%0.115CC..Hα-helixtrans-58.2-42.6177.5-71.6170.1000111.6C617 L620 L621 W630 A656 L657 R664 H665 I671C617-L660 HydrophobicContact CB-CD2 3.83Å; L620-L660 HydrophobicContact CB-CD2 4.48Å; L620-L660 HydrophobicContact CD1-CD2 4.34Å; L620-L660 HydrophobicContact CD1-CG 4.09Å; L621-L660 HydrophobicContact CD2-CD1 4.08Å; L621-L660 HydrophobicContact CG-CD2 4.27Å; W630-L660 HydrophobicContact CH2-CD1 4.2Å; W630-L660 HydrophobicContact CZ2-CD1 4.26Å; A656-L660 WeakPolarHBondContact O-CB 3.18Å; A656-L660 VanDerWaalsContact O-CG 3.29Å; A656-L660 WeakPolarHBondContact O-CG 3.46Å; A656-L660 PolarHBondContact O-N 3.46Å; L657-L660 PolarHBondContact O-N 3.35Å; L660-R664 PolarHBondContact O-N 2.95Å; L660-H665 HydrophobicContact CB-CB 4.27Å; L660-H665 HydrophobicContact CD2-CB 4.1Å; L660-H665 WeakPolarHBondContact O-CB 3.42Å; L660-H665 PolarHBondContact O-N 3.03Å; L660-I671 HydrophobicContact CB-CD1 4.49Å; L660-I671 HydrophobicContact CB-CG1 4.45Å
661M98.9Very high98.6Very high0 Ų023 Ų230%012%0.115CC..Hα-helixtrans-70.2-36.5177.7-75.1-168-70.700112.8L657 G659 V663 R664 I671 T716 R719 F720 L723 Y724L657-M661 HydrophobicContact CB-CE 4.16Å; L657-M661 VanDerWaalsContact O-CB 3.24Å; L657-M661 WeakPolarHBondContact O-CB 3.45Å; L657-M661 WeakPolarHBondContact O-CE 3.23Å; L657-M661 VanDerWaalsContact O-CG 3.28Å; L657-M661 WeakPolarHBondContact O-CG 3.42Å; L657-M661 PolarHBondContact O-N 3.2Å; G659-M661 VanDerWaalsContact C-N 3.3Å; G659-M661 PolarHBondContact O-N 3.45Å; M661-V663 VanDerWaalsContact C-N 3.29Å; M661-V663 PolarHBondContact O-N 3.26Å; M661-R664 WeakPolarHBondContact O-CD 3.15Å; M661-R664 PolarHBondContact O-N 3.49Å; M661-R664 PolarHBondContact O-NH1 3.33Å; M661-I671 HydrophobicContact CG-CD1 4.14Å; M661-I671 HydrophobicContact CG-CG2 4.09Å; M661-I671 HydrophobicContact SD-CG2 4.15Å; M661-T716 HydrophobicContact CE-CG2 3.78Å; M661-R719 HydrophobicContact CB-CG 4.35Å; M661-R719 HydrophobicContact CE-CB 4.02Å; M661-R719 HydrophobicContact CE-CG 4.11Å; M661-R719 HydrophobicContact SD-CB 4.43Å; M661-R719 HydrophobicContact SD-CG 4.17Å; M661-F720 HydrophobicContact CE-CB 4.36Å; M661-F720 VanDerWaalsContact SD-CA 3.6Å; M661-F720 HydrophobicContact SD-CB 3.84Å; M661-F720 HydrophobicContact SD-CD2 4.21Å; M661-L723 HydrophobicContact CB-CD1 3.78Å; M661-L723 HydrophobicContact CG-CD1 4.2Å; M661-L723 HydrophobicContact SD-CD1 4.2Å; M661-Y724 HydrophobicContact CG-CE2 4.1Å; M661-Y724 HydrophobicContact SD-CE2 4.09Å
662A98.8Very high98.6Very high6 Ų624.6 Ų24.65%0.0512%0.122CC..Hα-helixtrans-56.4-45.8178.900000111.1E595 A598 L658 G659 R664E595-A662 HydrophobicContact CG-CB 4.38Å; E595-A662 WeakPolarHBondContact OE2-CB 3.46Å; A598-A662 HydrophobicContact CB-CB 4Å; L658-A662 VanDerWaalsContact O-CB 3.27Å; L658-A662 WeakPolarHBondContact O-CB 3.49Å; L658-A662 PolarHBondContact O-N 3.32Å; G659-A662 WeakPolarHBondContact O-CB 3.36Å; G659-A662 PolarHBondContact O-N 3.03Å; A662-R664 VanDerWaalsContact C-N 3.29Å; A662-R664 PolarHBondContact O-N 3.09Å
663V98.8Very high98.6Very high0 Ų029.8 Ų29.80%014%0.142CC..THydrogen-bonded Turntrans-87.48177.8-60.90000114.1L594 A598 T603 Y604 V613 C617 G659 M661 H665L594-V663 HydrophobicContact CB-CG1 4.12Å; L594-V663 HydrophobicContact CD2-CG1 3.82Å; L594-V663 HydrophobicContact CD2-CG2 4.09Å; A598-V663 HydrophobicContact CB-CG1 4.11Å; T603-V663 WeakPolarHBondContact CA-O 3.04Å; T603-V663 WeakPolarHBondContact CB-O 3.39Å; Y604-V663 HydrophobicContact CD2-CB 4.48Å; Y604-V663 HydrophobicContact CD2-CG2 4.21Å; Y604-V663 WeakPolarHBondContact CD2-O 3.19Å; Y604-V663 HydrophobicContact CE2-CG2 4.31Å; Y604-V663 PolarHBondContact N-O 3.06Å; V613-V663 HydrophobicContact CG1-CB 3.82Å; V613-V663 HydrophobicContact CG1-CG1 3.88Å; V613-V663 HydrophobicContact CG1-CG2 3.89Å; V613-V663 HydrophobicContact CG2-CG1 4.48Å; C617-V663 VanDerWaalsContact SG-CG2 3.58Å; G659-V663 PolarHBondContact O-N 2.94Å; M661-V663 VanDerWaalsContact C-N 3.29Å; M661-V663 PolarHBondContact O-N 3.26Å; V663-H665 VanDerWaalsContact C-N 3.34Å; V663-H665 PolarHBondContact O-N 3.43Å
664R98.5Very high98.5Very high87 Ų8729.8 Ų29.833%0.32814%0.142SC..THydrogen-bonded Turntrans58.240.4177.2-48.2-62.4-179.4-128.44.4113.2Y604 K605 L660 M661 A662Y604-R664 WeakPolarHBondContact CB-O 3.47Å; K605-R664 HydrophobicContact CD-CG 4.28Å; K605-R664 HydrophobicContact CG-CB 4.15Å; K605-R664 HydrophobicContact CG-CG 4.34Å; L660-R664 PolarHBondContact O-N 2.95Å; M661-R664 WeakPolarHBondContact O-CD 3.15Å; M661-R664 PolarHBondContact O-N 3.49Å; M661-R664 PolarHBondContact O-NH1 3.33Å; A662-R664 VanDerWaalsContact C-N 3.29Å; A662-R664 PolarHBondContact O-N 3.09Å
665H98.5Very high98.5Very high19 Ų1929.8 Ų29.89%0.08814%0.142CC..  trans-52.6136-179.3-171.2-87.9000111.5Y604 C617 L621 L660 V663 D667Y604-H665 HydrophobicContact CD2-CB 4.48Å; Y604-H665 AromaticContact CE2-CD2 3.59Å; Y604-H665 AromaticContact CZ-CD2 3.59Å; C617-H665 VanDerWaalsContact CB-CD2 3.46Å; C617-H665 WeakPolarHBondContact CB-CD2 3.4Å; L621-H665 WeakPolarHBondContact CD1-CE1 3.48Å; L660-H665 HydrophobicContact CB-CB 4.27Å; L660-H665 HydrophobicContact CD2-CB 4.1Å; L660-H665 WeakPolarHBondContact O-CB 3.42Å; L660-H665 PolarHBondContact O-N 3.03Å; V663-H665 VanDerWaalsContact C-N 3.34Å; V663-H665 PolarHBondContact O-N 3.43Å; H665-D667 VanDerWaalsContact CE1-CB 3.44Å; H665-D667 WeakPolarHBondContact CE1-CB 3.34Å; H665-D667 WeakPolarHBondContact ND1-CB 3.49Å; H665-D667 PolarHBondContact ND1-N 3.2Å; H665-D667 VanDerWaalsContact ND1-N 3.16Å; H665-D667 PolarHBondContact O-N 3.04Å
666P97.4Very high98.5Very high94 Ų9433 Ų3361%0.6116%0.157SC*.SBendtrans-76.5-17.7-17028.8-36.9000114.8Y604 Q668Y604-P666 HydrophobicContact CD1-CG 4.13Å; Y604-P666 HydrophobicContact CE1-CG 4.42Å; P666-Q668 VanDerWaalsContact C-N 3.29Å; P666-Q668 PolarHBondContact O-N 2.64Å
667D97.7Very high98.5Very high60 Ų6033.3 Ų33.332%0.32116%0.159SC..  trans-75.280.4177.9-169-13.8000111.6H665 Q669 A670 I671H665-D667 VanDerWaalsContact CE1-CB 3.44Å; H665-D667 WeakPolarHBondContact CE1-CB 3.34Å; H665-D667 WeakPolarHBondContact ND1-CB 3.49Å; H665-D667 PolarHBondContact ND1-N 3.2Å; H665-D667 VanDerWaalsContact ND1-N 3.16Å; H665-D667 PolarHBondContact O-N 3.04Å; D667-Q669 VanDerWaalsContact C-N 3.28Å; D667-Q669 PolarHBondContact O-N 2.96Å; D667-Q669 PolarHBondContact OD1-N 3.38Å; D667-A670 HydrophobicContact CB-CB 4.22Å; D667-A670 VanDerWaalsContact CG-CB 3.5Å; D667-A670 PolarHBondContact O-N 3.04Å; D667-A670 PolarHBondContact OD1-N 2.7Å; D667-I671 PolarHBondContact O-N 3Å
668Q96.9Very high98.5Very high67 Ų6733.3 Ų33.331%0.31316%0.159SC..Hα-helixtrans-63.6-32.6177.5-179175.9-2600112.3P666 I671 E672 Y724P666-Q668 VanDerWaalsContact C-N 3.29Å; P666-Q668 PolarHBondContact O-N 2.64Å; Q668-I671 PolarHBondContact O-N 3.42Å; Q668-E672 HydrophobicContact CG-CG 4.19Å; Q668-E672 PolarHBondContact NE2-OE1 3.34Å; Q668-E672 WeakPolarHBondContact O-CB 3.42Å; Q668-E672 WeakPolarHBondContact O-CG 3.42Å; Q668-E672 PolarHBondContact O-N 3.03Å; Q668-Y724 HydrophobicContact CB-CE1 4.37Å; Q668-Y724 HydrophobicContact CG-CD1 3.96Å; Q668-Y724 HydrophobicContact CG-CE1 4.11Å
669Q97.9Very high98.5Very high139 Ų13933.5 Ų33.565%0.6516%0.16SC*.Hα-helixtrans-67-40.7-178.9-68.1-177.31.200111.3D667 I671 E672 R673D667-Q669 VanDerWaalsContact C-N 3.28Å; D667-Q669 PolarHBondContact O-N 2.96Å; D667-Q669 PolarHBondContact OD1-N 3.38Å; Q669-I671 VanDerWaalsContact C-N 3.31Å; Q669-I671 PolarHBondContact O-N 3.03Å; Q669-E672 PolarHBondContact O-N 3.46Å; Q669-R673 WeakPolarHBondContact O-CG 3.3Å; Q669-R673 PolarHBondContact O-N 3.14Å; Q669-R673 VanDerWaalsContact O-N 3.07Å
670A98.4Very high98.5Very high0 Ų040.1 Ų40.10%019%0.19CC..Hα-helixtrans-60.8-41.6173.800000112.3L621 Q624 D667 G674L621-A670 HydrophobicContact CD2-CB 3.51Å; Q624-A670 PolarHBondContact NE2-O 2.64Å; D667-A670 HydrophobicContact CB-CB 4.22Å; D667-A670 VanDerWaalsContact CG-CB 3.5Å; D667-A670 PolarHBondContact O-N 3.04Å; D667-A670 PolarHBondContact OD1-N 2.7Å; A670-G674 PolarHBondContact O-N 2.67Å
671I98.8Very high98.4Very high0 Ų042.3 Ų42.30%020%0.2CC..Hα-helixtrans-64.7-47.6176.9-65.2169000110.5L657 L660 M661 D667 Q668 Q669 R673 G674 V675 F720 Y724L657-I671 HydrophobicContact CD2-CB 4.28Å; L657-I671 HydrophobicContact CD2-CG2 4.07Å; L657-I671 WeakPolarHBondContact CD2-O 3.3Å; L660-I671 HydrophobicContact CB-CD1 4.49Å; L660-I671 HydrophobicContact CB-CG1 4.45Å; M661-I671 HydrophobicContact CG-CD1 4.14Å; M661-I671 HydrophobicContact CG-CG2 4.09Å; M661-I671 HydrophobicContact SD-CG2 4.15Å; D667-I671 PolarHBondContact O-N 3Å; Q668-I671 PolarHBondContact O-N 3.42Å; Q669-I671 VanDerWaalsContact C-N 3.31Å; Q669-I671 PolarHBondContact O-N 3.03Å; I671-R673 VanDerWaalsContact C-N 3.31Å; I671-R673 PolarHBondContact O-N 3.21Å; I671-G674 PolarHBondContact O-N 3.01Å; I671-G674 VanDerWaalsContact O-N 3.15Å; I671-V675 HydrophobicContact CG2-CG2 4.33Å; I671-V675 WeakPolarHBondContact O-CG2 3.49Å; I671-V675 PolarHBondContact O-N 3.34Å; I671-F720 HydrophobicContact CG2-CD2 3.67Å; I671-F720 HydrophobicContact CG2-CE2 3.88Å; I671-Y724 HydrophobicContact CD1-CE2 4.38Å; I671-Y724 VanDerWaalsContact CD1-OH 3.3Å; I671-Y724 WeakPolarHBondContact CD1-OH 3.44Å; I671-Y724 HydrophobicContact CG2-CE2 4.35Å
672E98.7Very high98.4Very high44 Ų4443.2 Ų43.221%0.20620%0.204CC..Hα-helixtrans-59.5-38179.5-78.3175.5167.600112.8Q668 Q669 G674 V675 Q676 F720 S727 L729Q668-E672 HydrophobicContact CG-CG 4.19Å; Q668-E672 PolarHBondContact NE2-OE1 3.34Å; Q668-E672 WeakPolarHBondContact O-CB 3.42Å; Q668-E672 WeakPolarHBondContact O-CG 3.42Å; Q668-E672 PolarHBondContact O-N 3.03Å; Q669-E672 PolarHBondContact O-N 3.46Å; E672-G674 PolarHBondContact O-N 2.93Å; E672-V675 PolarHBondContact O-N 3.03Å; E672-Q676 VanDerWaalsContact O-CB 3.3Å; E672-Q676 WeakPolarHBondContact O-CB 3.27Å; E672-Q676 PolarHBondContact O-N 3.41Å; E672-F720 HydrophobicContact CG-CE2 3.94Å; E672-F720 HydrophobicContact CG-CZ 3.74Å; E672-S727 VanDerWaalsContact OE1-CB 3.28Å; E672-S727 WeakPolarHBondContact OE1-CB 3.26Å; E672-S727 PolarHBondContact OE1-OG 3.26Å; E672-L729 HydrophobicContact CB-CD2 4.19Å; E672-L729 HydrophobicContact CG-CD2 4.4Å; E672-L729 VanDerWaalsContact O-CD2 3.28Å; E672-L729 WeakPolarHBondContact O-CD2 3.32Å
673R98.7Very high98.4Very high109 Ų10946.5 Ų46.541%0.41122%0.221SC..Hα-helixtrans-60-44.6175-72.3-167.9-56.6-90.27.5112.3Q669 I671 Q676 L677Q669-R673 WeakPolarHBondContact O-CG 3.3Å; Q669-R673 PolarHBondContact O-N 3.14Å; Q669-R673 VanDerWaalsContact O-N 3.07Å; I671-R673 VanDerWaalsContact C-N 3.31Å; I671-R673 PolarHBondContact O-N 3.21Å; R673-Q676 PolarHBondContact O-N 2.85Å; R673-L677 PolarHBondContact O-N 3.13Å; R673-L677 VanDerWaalsContact O-N 3.12Å
674G98.8Very high98.4Very high0 Ų050.3 Ų50.30%024%0.241CC..Hα-helixtrans-68.1-40.2177.900000112.7G628 A670 I671 E672 Q676 L677 L678G628-G674 WeakPolarHBondContact O-CA 3.41Å; G628-G674 PolarHBondContact O-N 2.82Å; A670-G674 PolarHBondContact O-N 2.67Å; I671-G674 PolarHBondContact O-N 3.01Å; I671-G674 VanDerWaalsContact O-N 3.15Å; E672-G674 PolarHBondContact O-N 2.93Å; G674-Q676 VanDerWaalsContact C-N 3.33Å; G674-Q676 PolarHBondContact O-N 3.27Å; G674-L677 WeakPolarHBondContact O-CB 3.43Å; G674-L677 PolarHBondContact O-N 2.99Å; G674-L678 WeakPolarHBondContact O-CG 3.48Å; G674-L678 PolarHBondContact O-N 3.04Å; G674-L678 VanDerWaalsContact O-N 3.11Å
675V98.9Very high98.3Very high0 Ų047.5 Ų47.50%023%0.232CC..Hα-helixtrans-61.6-43.3174.4173.40000110.5A74 L657 I671 E672 L677 L678 V679 L717 F720 L729A74-V675 HydrophobicContact CB-CG1 3.78Å; L657-V675 HydrophobicContact CD1-CG2 4.32Å; I671-V675 HydrophobicContact CG2-CG2 4.33Å; I671-V675 WeakPolarHBondContact O-CG2 3.49Å; I671-V675 PolarHBondContact O-N 3.34Å; E672-V675 PolarHBondContact O-N 3.03Å; V675-L677 VanDerWaalsContact C-N 3.29Å; V675-L677 PolarHBondContact O-N 3.3Å; V675-L678 PolarHBondContact O-N 3.11Å; V675-L678 VanDerWaalsContact O-N 3.16Å; V675-V679 WeakPolarHBondContact O-CG2 3.26Å; V675-V679 PolarHBondContact O-N 3.14Å; V675-L717 HydrophobicContact CG1-CD2 3.66Å; V675-F720 HydrophobicContact CG1-CD1 3.8Å; V675-F720 HydrophobicContact CG1-CE1 4.01Å; V675-F720 HydrophobicContact CG1-CG 4.17Å; V675-F720 HydrophobicContact CG2-CB 4.06Å; V675-F720 HydrophobicContact CG2-CD1 4.19Å; V675-F720 HydrophobicContact CG2-CD2 3.69Å; V675-F720 HydrophobicContact CG2-CE2 4.17Å; V675-F720 HydrophobicContact CG2-CG 3.7Å; V675-L729 HydrophobicContact CB-CD2 3.85Å; V675-L729 HydrophobicContact CG1-CD2 3.63Å; V675-L729 HydrophobicContact CG1-CG 4Å
676Q98.6Very high98.3Very high68 Ų6846.6 Ų46.632%0.31823%0.228SC..Hα-helixtrans-60.1-40.3177.6-177.3656600111.6E672 R673 G674 V679 Q680 L729E672-Q676 VanDerWaalsContact O-CB 3.3Å; E672-Q676 WeakPolarHBondContact O-CB 3.27Å; E672-Q676 PolarHBondContact O-N 3.41Å; R673-Q676 PolarHBondContact O-N 2.85Å; G674-Q676 VanDerWaalsContact C-N 3.33Å; G674-Q676 PolarHBondContact O-N 3.27Å; Q676-V679 PolarHBondContact O-N 2.67Å; Q676-Q680 WeakPolarHBondContact O-CB 3.17Å; Q676-Q680 VanDerWaalsContact O-CG 3.26Å; Q676-Q680 WeakPolarHBondContact O-CG 3.2Å; Q676-Q680 PolarHBondContact O-N 2.91Å; Q676-L729 HydrophobicContact CB-CD2 4.08Å; Q676-L729 VanDerWaalsContact OE1-CD1 3.23Å
677L98.7Very high98.4Very high7 Ų742.6 Ų42.64%0.03720%0.202CC..Hα-helixtrans-62.3-44.1174.7178.8137.2000111.8D627 A648 T653 R673 G674 V675 V679 Q680 K681D627-L677 HydrophobicContact CB-CD1 3.8Å; D627-L677 WeakPolarHBondContact O-CD1 3.27Å; D627-L677 WeakPolarHBondContact OD2-CD1 3.36Å; A648-L677 HydrophobicContact CB-CD1 3.93Å; A648-L677 HydrophobicContact CB-CD2 4.39Å; T653-L677 HydrophobicContact CG2-CD2 4.17Å; R673-L677 PolarHBondContact O-N 3.13Å; R673-L677 VanDerWaalsContact O-N 3.12Å; G674-L677 WeakPolarHBondContact O-CB 3.43Å; G674-L677 PolarHBondContact O-N 2.99Å; V675-L677 VanDerWaalsContact C-N 3.29Å; V675-L677 PolarHBondContact O-N 3.3Å; L677-V679 VanDerWaalsContact C-N 3.34Å; L677-V679 PolarHBondContact O-N 3.4Å; L677-Q680 PolarHBondContact O-N 3.02Å; L677-K681 HydrophobicContact CD2-CD 3.92Å; L677-K681 HydrophobicContact CD2-CG 4.48Å; L677-K681 HydrophobicContact CG-CD 4.4Å; L677-K681 WeakPolarHBondContact O-CG 3.49Å; L677-K681 PolarHBondContact O-N 2.84Å
678L98.8Very high98.4Very high0 Ų039.8 Ų39.80%019%0.186CC..Hα-helixtrans-62.6-40.9177.4-65.7177.9000112.3I650 T653 L657 G674 V675 K681 Q682 W688 T716 L717I650-L678 HydrophobicContact CG1-CD2 4.49Å; I650-L678 HydrophobicContact CG2-CD2 4.17Å; T653-L678 HydrophobicContact CG2-CD1 4.47Å; T653-L678 HydrophobicContact CG2-CD2 4.03Å; T653-L678 HydrophobicContact CG2-CG 4.09Å; L657-L678 HydrophobicContact CD1-CD1 3.94Å; G674-L678 WeakPolarHBondContact O-CG 3.48Å; G674-L678 PolarHBondContact O-N 3.04Å; G674-L678 VanDerWaalsContact O-N 3.11Å; V675-L678 PolarHBondContact O-N 3.11Å; V675-L678 VanDerWaalsContact O-N 3.16Å; L678-K681 PolarHBondContact O-N 2.76Å; L678-Q682 PolarHBondContact O-N 3.21Å; L678-W688 PolarHBondContact O-NE1 3.45Å; L678-T716 HydrophobicContact CD1-CG2 3.88Å; L678-L717 HydrophobicContact CB-CD2 4.25Å
679V98.6Very high98.5Very high4 Ų438.7 Ų38.72%0.02419%0.185CC..Hα-helixtrans-63.1-44175.1172.50000110.7S71 A77 V675 Q676 L677 K681 Q682 L717S71-V679 WeakPolarHBondContact O-CG1 3.27Å; A77-V679 HydrophobicContact CB-CG2 3.99Å; V675-V679 WeakPolarHBondContact O-CG2 3.26Å; V675-V679 PolarHBondContact O-N 3.14Å; Q676-V679 PolarHBondContact O-N 2.67Å; L677-V679 VanDerWaalsContact C-N 3.34Å; L677-V679 PolarHBondContact O-N 3.4Å; V679-K681 VanDerWaalsContact C-N 3.35Å; V679-K681 PolarHBondContact O-N 2.77Å; V679-Q682 WeakPolarHBondContact O-CB 3.47Å; V679-Q682 PolarHBondContact O-N 3.14Å; V679-L717 HydrophobicContact CG2-CD2 4Å
680Q98.3Very high98.5Very high138 Ų13835.1 Ų35.165%0.64517%0.168SC*.Hα-helixtrans-68.6-30.3179.9-75.1172.6300113.6Q676 L677 Q682Q676-Q680 WeakPolarHBondContact O-CB 3.17Å; Q676-Q680 VanDerWaalsContact O-CG 3.26Å; Q676-Q680 WeakPolarHBondContact O-CG 3.2Å; Q676-Q680 PolarHBondContact O-N 2.91Å; L677-Q680 PolarHBondContact O-N 3.02Å; Q680-Q682 VanDerWaalsContact C-N 3.31Å
681K98.5Very high98.5Very high46 Ų4636.6 Ų36.620%0.218%0.175CC..Hα-helixtrans-78.5-12177.5-75.7-168.8174.3-164.50113.9A648 I650 L677 L678 V679 L683 P689 E691A648-K681 PolarHBondContact O-NZ 3.19Å; I650-K681 HydrophobicContact CD1-CB 4.49Å; I650-K681 HydrophobicContact CD1-CD 4.17Å; I650-K681 HydrophobicContact CG1-CD 3.83Å; L677-K681 HydrophobicContact CD2-CD 3.92Å; L677-K681 HydrophobicContact CD2-CG 4.48Å; L677-K681 HydrophobicContact CG-CD 4.4Å; L677-K681 WeakPolarHBondContact O-CG 3.49Å; L677-K681 PolarHBondContact O-N 2.84Å; L678-K681 PolarHBondContact O-N 2.76Å; V679-K681 VanDerWaalsContact C-N 3.35Å; V679-K681 PolarHBondContact O-N 2.77Å; K681-L683 PolarHBondContact O-N 2.89Å; K681-P689 WeakPolarHBondContact O-CD 3.38Å; K681-E691 IonicContact NZ-OE1 3.15Å; K681-E691 PolarHBondContact NZ-OE1 3.05Å
682Q98.7Very high98.5Very high20 Ų2037.9 Ų37.99%0.09318%0.182CC..  trans-66.2134.3-178.4-166.8177.736.700110.9S71 A77 L678 V679 Q680 G686 W688S71-Q682 PolarHBondContact OG-OE1 3.25Å; A77-Q682 VanDerWaalsContact CA-OE1 3.22Å; A77-Q682 VanDerWaalsContact CB-OE1 3.3Å; A77-Q682 PolarHBondContact O-NE2 2.66Å; L678-Q682 PolarHBondContact O-N 3.21Å; V679-Q682 WeakPolarHBondContact O-CB 3.47Å; V679-Q682 PolarHBondContact O-N 3.14Å; Q680-Q682 VanDerWaalsContact C-N 3.31Å; Q682-G686 PolarHBondContact NE2-O 3.47Å; Q682-W688 HydrophobicContact CB-CZ2 3.96Å; Q682-W688 HydrophobicContact CG-CD2 4.21Å; Q682-W688 HydrophobicContact CG-CH2 4.12Å; Q682-W688 HydrophobicContact CG-CZ2 3.71Å
683L98.5Very high98.5Very high74 Ų7436 Ų3639%0.38717%0.173SC..  trans-74.5155.7173.9-58.1-177.6000110.4K681 N685 G686 D687K681-L683 PolarHBondContact O-N 2.89Å; L683-N685 WeakPolarHBondContact CB-OD1 3.47Å; L683-N685 PolarHBondContact O-N 3Å; L683-N685 VanDerWaalsContact O-N 3.1Å; L683-G686 PolarHBondContact O-N 3.35Å; L683-D687 WeakPolarHBondContact CB-O 3.35Å; L683-D687 HydrophobicContact CD1-CB 4.23Å; L683-D687 PolarHBondContact N-O 2.76Å
684L97.9Very high98.5Very high81 Ų8131.1 Ų31.142%0.42416%0.156SC..THydrogen-bonded Turntrans-61.6-24.9-174.7-61.8-175.6000113.7D67 S68 A70 G686D67-L684 HydrophobicContact CB-CB 3.85Å; D67-L684 HydrophobicContact CB-CD1 4.43Å; S68-L684 PolarHBondContact N-O 3.39Å; S68-L684 PolarHBondContact OG-O 3.06Å; A70-L684 HydrophobicContact CB-CD2 4.33Å; L684-G686 VanDerWaalsContact C-N 3.34Å
685N97.5Very high98.5Very high27 Ų2731.1 Ų31.114%0.14416%0.156CC..THydrogen-bonded Turntrans-83.9-5.6176.167.22.2000114V65 F84 L683 D687V65-N685 HydrophobicContact CG1-CB 4.13Å; V65-N685 HydrophobicContact CG2-CB 4.13Å; F84-N685 WeakPolarHBondContact CD2-O 3.14Å; L683-N685 WeakPolarHBondContact CB-OD1 3.47Å; L683-N685 PolarHBondContact O-N 3Å; L683-N685 VanDerWaalsContact O-N 3.1Å; N685-D687 WeakPolarHBondContact OD1-CB 3.32Å; N685-D687 PolarHBondContact OD1-N 3.02Å
686G98.2Very high98.5Very high0 Ų031.2 Ų31.20%016%0.157CC..SBendtrans98-8.5-179.500000116.1G81 Q682 L683 L684 W688G81-G686 WeakPolarHBondContact CA-O 3.4Å; Q682-G686 PolarHBondContact NE2-O 3.47Å; L683-G686 PolarHBondContact O-N 3.35Å; L684-G686 VanDerWaalsContact C-N 3.34Å; G686-W688 VanDerWaalsContact O-CZ3 3.28Å; G686-W688 WeakPolarHBondContact O-CZ3 3.04Å
687D98.6Very high98.5Very high11 Ų1129.9 Ų29.96%0.05915%0.15CC..  trans-73.4173.6171.8-158.7-3.4000110.7H55 F84 L683 N685 R709 N710H55-D687 IonicContact CD2-OD2 2.83Å; H55-D687 IonicContact CE1-OD2 3.86Å; H55-D687 IonicContact NE2-OD2 3.07Å; H55-D687 PolarHBondContact NE2-OD2 3.33Å; F84-D687 HydrophobicContact CD1-CB 3.76Å; F84-D687 HydrophobicContact CD2-CB 4.14Å; F84-D687 HydrophobicContact CE1-CB 3.39Å; F84-D687 WeakPolarHBondContact CE1-OD2 3.29Å; F84-D687 HydrophobicContact CE2-CB 3.79Å; F84-D687 HydrophobicContact CG-CB 4.14Å; F84-D687 HydrophobicContact CZ-CB 3.42Å; F84-D687 VanDerWaalsContact CZ-CB 3.42Å; F84-D687 VanDerWaalsContact CZ-CG 3.41Å; F84-D687 VanDerWaalsContact CZ-OD2 3.27Å; F84-D687 WeakPolarHBondContact CZ-OD2 3.29Å; L683-D687 WeakPolarHBondContact CB-O 3.35Å; L683-D687 HydrophobicContact CD1-CB 4.23Å; L683-D687 PolarHBondContact N-O 2.76Å; N685-D687 WeakPolarHBondContact OD1-CB 3.32Å; N685-D687 PolarHBondContact OD1-N 3.02Å; D687-R709 IonicContact OD1-NE 2.84Å; D687-N710 PolarHBondContact OD1-ND2 2.86Å; D687-N710 PolarHBondContact OD1-OD1 3Å; D687-N710 VanDerWaalsContact OD1-OD1 3.09Å
688W98.8Very high98.4Very high1 Ų130.1 Ų30.10%0.00415%0.151CC..  trans-121.6149.6168.4-82-92.2000110.9I650 L678 Q682 G686 R709 P713 I714 L717I650-W688 HydrophobicContact CD1-CB 3.86Å; I650-W688 HydrophobicContact CD1-CG 4.17Å; L678-W688 PolarHBondContact O-NE1 3.45Å; Q682-W688 HydrophobicContact CB-CZ2 3.96Å; Q682-W688 HydrophobicContact CG-CD2 4.21Å; Q682-W688 HydrophobicContact CG-CH2 4.12Å; Q682-W688 HydrophobicContact CG-CZ2 3.71Å; G686-W688 VanDerWaalsContact O-CZ3 3.28Å; G686-W688 WeakPolarHBondContact O-CZ3 3.04Å; W688-R709 HydrophobicContact CB-CB 4.45Å; W688-R709 VanDerWaalsContact CB-O 3.28Å; W688-R709 WeakPolarHBondContact CB-O 3.37Å; W688-R709 VanDerWaalsContact O-CD 3.29Å; W688-R709 WeakPolarHBondContact O-CD 3.32Å; W688-R709 PolarHBondContact O-NE 3.25Å; W688-P713 HydrophobicContact CD2-CB 3.9Å; W688-P713 HydrophobicContact CD2-CG 4.07Å; W688-P713 HydrophobicContact CE3-CB 4.14Å; W688-P713 HydrophobicContact CE3-CG 4.46Å; W688-P713 HydrophobicContact CG-CG 4.3Å; W688-P713 HydrophobicContact CH2-CB 3.89Å; W688-P713 HydrophobicContact CZ2-CB 3.65Å; W688-P713 HydrophobicContact CZ3-CB 4.13Å; W688-I714 HydrophobicContact CZ3-CG1 4.28Å; W688-L717 HydrophobicContact CH2-CD1 4.29Å; W688-L717 HydrophobicContact CZ2-CD1 3.91Å
689P98.6Very high98.4Very high43 Ų4330.8 Ų30.828%0.27915%0.154SC..  trans-64145.9-179.927.8-35.3000111.5I650 K681I650-P689 HydrophobicContact CD1-CG 4.08Å; K681-P689 WeakPolarHBondContact O-CD 3.38Å
690Q98.6Very high98.4Very high64 Ų6430.8 Ų30.830%0.29915%0.154SC..  trans-68.8138.4164.6-178.760.843.400109.3
691E98.6Very high98.4Very high31 Ų3124.2 Ų24.215%0.14512%0.124CC..  trans-130.2-153.1177.9-57.9176.114700108.9G11 Q649 I650 K681G11-E691 WeakPolarHBondContact CA-O 3.43Å; Q649-E691 VanDerWaalsContact CA-OE2 3.24Å; Q649-E691 WeakPolarHBondContact CA-OE2 3.45Å; Q649-E691 VanDerWaalsContact OE1-CB 3.27Å; I650-E691 WeakPolarHBondContact CB-OE2 3.3Å; I650-E691 WeakPolarHBondContact CG1-OE2 3.41Å; I650-E691 PolarHBondContact N-OE2 2.89Å; K681-E691 IonicContact NZ-OE1 3.15Å; K681-E691 PolarHBondContact NZ-OE1 3.05Å
692N98.7Very high98.4Very high27 Ų2722 Ų2214%0.14411%0.114CC..SBendtrans-63159.6179.8-61.5-11000111.8R10 E147 Q649 H651R10-N692 WeakPolarHBondContact CB-OD1 3.46Å; E147-N692 WeakPolarHBondContact OE1-CA 3.49Å; Q649-N692 VanDerWaalsContact OE1-CB 3.26Å; H651-N692 PolarHBondContact CE1-O 3.44Å
693I98.6Very high98.4Very high5 Ų521.3 Ų21.33%0.02611%0.111CC..  trans-62.2138.8-179.6-160.8150.4000111.9I146 E147 F634 A702 I703I146-I693 HydrophobicContact CD1-CD1 3.96Å; I146-I693 HydrophobicContact CG1-CD1 3.94Å; E147-I693 HydrophobicContact CB-CG2 4.49Å; E147-I693 HydrophobicContact CG-CB 4.18Å; E147-I693 HydrophobicContact CG-CG2 3.75Å; E147-I693 PolarHBondContact OE1-N 2.91Å; F634-I693 HydrophobicContact CD2-CG2 4.19Å; I693-A702 HydrophobicContact CB-CB 4.42Å; I693-A702 HydrophobicContact CD1-CB 3.54Å; I693-A702 HydrophobicContact CG1-CB 3.99Å; I693-A702 HydrophobicContact CG2-CB 3.67Å; I693-I703 VanDerWaalsContact CG1-O 3.27Å; I693-I703 WeakPolarHBondContact CG1-O 3.43Å
694S98.6Very high98.5Very high6 Ų618.1 Ų18.14%0.04210%0.095CC..  trans-108.2-19-171.2560000114.4G583 V584G583-S694 CarbonylContact C-O 3.51Å; G583-S694 VanDerWaalsContact CA-O 3.32Å; G583-S694 WeakPolarHBondContact CA-O 3.49Å; V584-S694 PolarHBondContact N-O 2.99Å
695G98.7Very high98.5Very high0 Ų015 Ų150%08%0.077CC..EExtended strand (participates in β ladder)trans-101.5151-177.600000113A702 I703G695-A702 WeakPolarHBondContact O-CA 3.33Å; G695-I703 CarbonylContact C-O 3.58Å; G695-I703 WeakPolarHBondContact CA-O 3.35Å; G695-I703 PolarHBondContact N-O 3.5Å; G695-I703 PolarHBondContact O-N 3.39Å
696V98.8Very high98.5Very high3 Ų315 Ų152%0.0188%0.078CC..EExtended strand (participates in β ladder)trans-143.5150.4174.760.80000109.8W582 V584 F634 C637 C701W582-V696 CarbonylContact C-O 3.45Å; W582-V696 VanDerWaalsContact CA-O 3.32Å; W582-V696 WeakPolarHBondContact CA-O 3.38Å; W582-V696 PolarHBondContact O-N 2.85Å; V584-V696 HydrophobicContact CG2-CB 4.09Å; V584-V696 HydrophobicContact CG2-CG1 4.31Å; F634-V696 HydrophobicContact CE2-CB 3.92Å; F634-V696 HydrophobicContact CE2-CG2 3.69Å; F634-V696 HydrophobicContact CZ-CG2 3.98Å; C637-V696 HydrophobicContact CB-CG2 3.92Å; V696-C701 CarbonylContact C-O 3.59Å; V696-C701 WeakPolarHBondContact CA-O 3.07Å
697F97.8Very high98.6Very high40 Ų4015 Ų1518%0.1758%0.079CC..EExtended strand (participates in β ladder)trans-137.1148.4159.857.8-91000110.3P102 F104 F522 W582 K699 C701 I703P102-F697 HydrophobicContact CB-CZ 4.37Å; P102-F697 HydrophobicContact CG-CE1 3.7Å; P102-F697 HydrophobicContact CG-CZ 3.73Å; F104-F697 HydrophobicContact CZ-CE2 4.29Å; F104-F697 HydrophobicContact CZ-CZ 4.09Å; F522-F697 HydrophobicContact CE1-CE2 4.19Å; W582-F697 HydrophobicContact CE3-CB 4.38Å; W582-F697 HydrophobicContact CZ3-CB 4.01Å; F697-K699 PolarHBondContact O-N 3.03Å; F697-K699 VanDerWaalsContact O-N 3.1Å; F697-C701 HydrophobicContact CD1-CB 4.4Å; F697-C701 HydrophobicContact CD2-CB 3.96Å; F697-C701 HydrophobicContact CE1-CB 3.97Å; F697-C701 HydrophobicContact CE2-CB 3.49Å; F697-C701 VanDerWaalsContact CE2-CB 3.49Å; F697-C701 HydrophobicContact CG-CB 4.41Å; F697-C701 HydrophobicContact CZ-CB 3.51Å; F697-C701 WeakPolarHBondContact CZ-SG 3.5Å; F697-C701 PolarHBondContact N-O 3.41Å; F697-C701 PolarHBondContact O-N 3.19Å; F697-I703 HydrophobicContact CD1-CB 4.25Å; F697-I703 HydrophobicContact CD1-CG2 4.15Å; F697-I703 HydrophobicContact CE1-CB 4.11Å; F697-I703 HydrophobicContact CE1-CD1 4.19Å
698N98.1Very high98.6Very high12 Ų1214.7 Ų14.76%0.0648%0.076CC..THydrogen-bonded Turntrans51.437.2175.4-53.8116.5000114.4W231 F522 G523 D524 I525 S700W231-N698 WeakPolarHBondContact CH2-OD1 3.49Å; W231-N698 WeakPolarHBondContact CZ3-ND2 3.36Å; W231-N698 WeakPolarHBondContact CZ3-OD1 3.47Å; F522-N698 HydrophobicContact CB-CB 3.95Å; F522-N698 HydrophobicContact CD1-CB 4.28Å; F522-N698 HydrophobicContact CG-CB 4.4Å; G523-N698 PolarHBondContact N-O 3.2Å; G523-N698 CarbonylContact O-C 3.57Å; G523-N698 WeakPolarHBondContact O-CA 3.36Å; G523-N698 WeakPolarHBondContact O-CB 3.46Å; D524-N698 PolarHBondContact O-ND2 2.86Å; I525-N698 HydrophobicContact CG2-CB 3.95Å; N698-S700 PolarHBondContact O-N 2.87Å; N698-S700 PolarHBondContact O-OG 2.98Å
699K98.3Very high98.6Very high13 Ų1316.4 Ų16.46%0.0578%0.083CC..THydrogen-bonded Turntrans69.6-39.5178.2-53.3-66.1-174.1-71.40116.3Y287 D524 E579 C637 F697Y287-K699 HydrophobicContact CE1-CB 3.9Å; Y287-K699 HydrophobicContact CE1-CG 4.38Å; Y287-K699 WeakPolarHBondContact OH-CB 3.25Å; D524-K699 WeakPolarHBondContact OD2-CE 3.49Å; D524-K699 IonicContact OD2-NZ 2.73Å; D524-K699 PolarHBondContact OD2-NZ 3.13Å; E579-K699 VanDerWaalsContact OE1-CE 3.31Å; E579-K699 WeakPolarHBondContact OE1-CE 3.4Å; C637-K699 CarbonylContact C-O 3.56Å; C637-K699 WeakPolarHBondContact CB-O 3.49Å; F697-K699 PolarHBondContact O-N 3.03Å; F697-K699 VanDerWaalsContact O-N 3.1Å
700S98.3Very high98.6Very high5 Ų514.4 Ų14.44%0.0357%0.07CC..THydrogen-bonded Turntrans-110.1-9.9-164.257.30000114.8L144 H145 V521 N698L144-S700 WeakPolarHBondContact CD2-O 3.28Å; H145-S700 PolarHBondContact CD2-O 2.88Å; H145-S700 PolarHBondContact NE2-O 3.29Å; V521-S700 VanDerWaalsContact O-CB 3.31Å; V521-S700 WeakPolarHBondContact O-CB 3.05Å; V521-S700 PolarHBondContact O-OG 2.9Å; N698-S700 PolarHBondContact O-N 2.87Å; N698-S700 PolarHBondContact O-OG 2.98Å
701C98.7Very high98.6Very high0 Ų011.4 Ų11.40%06%0.056CC..EExtended strand (participates in β ladder)trans-114.4122-178.2-163.60000112.7L144 F522 V696 F697L144-C701 HydrophobicContact CD2-CB 4.17Å; F522-C701 HydrophobicContact CD1-CB 4.44Å; F522-C701 HydrophobicContact CE1-CB 3.94Å; V696-C701 CarbonylContact C-O 3.59Å; V696-C701 WeakPolarHBondContact CA-O 3.07Å; F697-C701 HydrophobicContact CD1-CB 4.4Å; F697-C701 HydrophobicContact CD2-CB 3.96Å; F697-C701 HydrophobicContact CE1-CB 3.97Å; F697-C701 HydrophobicContact CE2-CB 3.49Å; F697-C701 VanDerWaalsContact CE2-CB 3.49Å; F697-C701 HydrophobicContact CG-CB 4.41Å; F697-C701 HydrophobicContact CZ-CB 3.51Å; F697-C701 WeakPolarHBondContact CZ-SG 3.5Å; F697-C701 PolarHBondContact N-O 3.41Å; F697-C701 PolarHBondContact O-N 3.19Å
702A98.8Very high98.6Very high0 Ų010 Ų100%05%0.049CC..EExtended strand (participates in β ladder)trans-81.9148.3175.900000112.6P102 H145 F634 I693 G695P102-A702 WeakPolarHBondContact CD-O 3.4Å; H145-A702 HydrophobicContact CB-CB 4.13Å; H145-A702 VanDerWaalsContact ND1-CB 3.3Å; H145-A702 WeakPolarHBondContact ND1-CB 3.4Å; F634-A702 HydrophobicContact CD2-CB 3.65Å; F634-A702 VanDerWaalsContact CE2-CA 3.47Å; F634-A702 HydrophobicContact CE2-CB 3.4Å; F634-A702 HydrophobicContact CG-CB 4.37Å; F634-A702 HydrophobicContact CZ-CB 3.92Å; I693-A702 HydrophobicContact CB-CB 4.42Å; I693-A702 HydrophobicContact CD1-CB 3.54Å; I693-A702 HydrophobicContact CG1-CB 3.99Å; I693-A702 HydrophobicContact CG2-CB 3.67Å; G695-A702 WeakPolarHBondContact O-CA 3.33Å
703I98.8Very high98.6Very high4 Ų48.7 Ų8.72%0.0214%0.042CC..EExtended strand (participates in β ladder)trans-143.1142.8174.2-165.7159.1000111.1Y99 P102 I693 G695 F697 Y705Y99-I703 HydrophobicContact CD1-CD1 3.87Å; Y99-I703 HydrophobicContact CD2-CD1 4.4Å; Y99-I703 HydrophobicContact CD2-CG1 4.28Å; Y99-I703 HydrophobicContact CE1-CD1 3.39Å; Y99-I703 HydrophobicContact CE1-CG1 4.26Å; Y99-I703 HydrophobicContact CE2-CD1 3.95Å; Y99-I703 HydrophobicContact CE2-CG1 3.98Å; Y99-I703 HydrophobicContact CG-CD1 4.34Å; Y99-I703 VanDerWaalsContact CZ-CD1 3.42Å; P102-I703 HydrophobicContact CG-CD1 4.46Å; I693-I703 VanDerWaalsContact CG1-O 3.27Å; I693-I703 WeakPolarHBondContact CG1-O 3.43Å; G695-I703 CarbonylContact C-O 3.58Å; G695-I703 WeakPolarHBondContact CA-O 3.35Å; G695-I703 PolarHBondContact N-O 3.5Å; G695-I703 PolarHBondContact O-N 3.39Å; F697-I703 HydrophobicContact CD1-CB 4.25Å; F697-I703 HydrophobicContact CD1-CG2 4.15Å; F697-I703 HydrophobicContact CE1-CB 4.11Å; F697-I703 HydrophobicContact CE1-CD1 4.19Å; I703-Y705 HydrophobicContact CG2-CE2 4.2Å
704S98.8Very high98.6Very high7 Ų78.4 Ų8.45%0.0494%0.041CC..  trans-79.3126.6-177.2-65.30000111.4Y99 G100Y99-S704 WeakPolarHBondContact CD2-O 3.32Å; G100-S704 WeakPolarHBondContact O-CB 3.04Å; G100-S704 PolarHBondContact O-N 2.94Å; G100-S704 PolarHBondContact O-OG 3.03Å
705Y98.8Very high98.7Very high16 Ų168.4 Ų8.46%0.0634%0.04CC..  trans-105.387.8160.7-75.9-82.8000109.8Y99 W388 F445 I703 S707 Y708Y99-Y705 HydrophobicContact CE2-CD1 4Å; Y99-Y705 AromaticContact CE2-CE1 3.72Å; Y99-Y705 HydrophobicContact CE2-CE1 3.72Å; Y99-Y705 HydrophobicContact CE2-CE2 4.48Å; Y99-Y705 HydrophobicContact CE2-CG 4.5Å; Y99-Y705 AromaticContact CE2-CZ 3.97Å; Y99-Y705 PolarHBondContact OH-OH 3.31Å; W388-Y705 AromaticContact CD1-CD1 3.91Å; W388-Y705 AromaticContact CD1-CE1 3.52Å; W388-Y705 HydrophobicContact CG-CE1 4.44Å; W388-Y705 AromaticContact NE1-CD1 3.85Å; W388-Y705 AromaticContact NE1-CE1 3.39Å; F445-Y705 AromaticContact CE2-CE1 3.98Å; F445-Y705 HydrophobicContact CE2-CE1 3.98Å; F445-Y705 AromaticContact CZ-CE1 3.75Å; F445-Y705 HydrophobicContact CZ-CE1 3.75Å; I703-Y705 HydrophobicContact CG2-CE2 4.2Å; Y705-S707 PolarHBondContact O-N 3.28Å; Y705-Y708 VanDerWaalsContact CB-CD2 3.43Å; Y705-Y708 VanDerWaalsContact CB-CG 3.44Å; Y705-Y708 HydrophobicContact CD1-CD1 4.28Å; Y705-Y708 AromaticContact CD1-CE1 3.59Å; Y705-Y708 HydrophobicContact CD1-CE1 3.59Å; Y705-Y708 HydrophobicContact CD1-CE2 4.13Å; Y705-Y708 AromaticContact CD1-CZ 3.49Å; Y705-Y708 VanDerWaalsContact CD1-CZ 3.49Å; Y705-Y708 HydrophobicContact CD2-CD2 4.25Å; Y705-Y708 AromaticContact CD2-CE2 3.59Å; Y705-Y708 HydrophobicContact CD2-CE2 3.59Å; Y705-Y708 AromaticContact CD2-CZ 3.77Å; Y705-Y708 HydrophobicContact CE1-CE1 4.33Å; Y705-Y708 AromaticContact CE1-CZ 3.99Å; Y705-Y708 HydrophobicContact CE2-CE2 4.29Å; Y705-Y708 HydrophobicContact CG-CD1 4.13Å; Y705-Y708 AromaticContact CG-CD2 3.96Å; Y705-Y708 HydrophobicContact CG-CD2 3.96Å; Y705-Y708 AromaticContact CG-CE1 3.72Å; Y705-Y708 HydrophobicContact CG-CE1 3.72Å; Y705-Y708 AromaticContact CG-CE2 3.5Å; Y705-Y708 HydrophobicContact CG-CE2 3.5Å; Y705-Y708 HydrophobicContact CG-CG 4.25Å; Y705-Y708 AromaticContact CG-CZ 3.37Å; Y705-Y708 WeakPolarHBondContact O-CB 3.31Å; Y705-Y708 PolarHBondContact O-N 3.39Å; Y705-Y708 VanDerWaalsContact O-N 3.16Å
706T98.4Very high98.7Very high26 Ų268.4 Ų8.416%0.164%0.04CC..THydrogen-bonded Turntrans-53.7-41.2-174.8-70.40000113D98 Y708 R709D98-T706 WeakPolarHBondContact CB-OG1 3.34Å; D98-T706 PolarHBondContact N-OG1 3.4Å; D98-T706 PolarHBondContact O-OG1 3.14Å; T706-Y708 VanDerWaalsContact C-N 3.28Å; T706-Y708 PolarHBondContact O-N 3.1Å; T706-R709 PolarHBondContact O-NH1 2.68Å
707S98.7Very high98.7Very high2 Ų28.2 Ų8.21%0.0144%0.039CC..THydrogen-bonded Turntrans-70.9-20.5-174.6-640000113.7Y85 D389 Y705 R709 N710 V711Y85-S707 WeakPolarHBondContact OH-CB 3.15Å; Y85-S707 PolarHBondContact OH-OG 3.09Å; D389-S707 PolarHBondContact OD2-OG 3.41Å; Y705-S707 PolarHBondContact O-N 3.28Å; S707-R709 VanDerWaalsContact C-N 3.32Å; S707-R709 PolarHBondContact O-N 3.13Å; S707-N710 PolarHBondContact O-N 2.78Å; S707-V711 WeakPolarHBondContact O-CB 3.31Å; S707-V711 WeakPolarHBondContact O-CG2 3.46Å; S707-V711 PolarHBondContact O-N 2.89Å
708Y98.9Very high98.7Very high3 Ų36.5 Ų6.51%0.0123%0.032CC..Hα-helixtrans-61.8-36.1-171.3-7911.6000113.5W388 F392 W655 Y705 T706 N710 F712 P713W388-Y708 AromaticContact NE1-CE1 3.62Å; W388-Y708 AromaticContact NE1-CZ 3.66Å; W388-Y708 PolarHBondContact NE1-OH 3.15Å; F392-Y708 HydrophobicContact CD2-CE1 4.34Å; W655-Y708 HydrophobicContact CH2-CD2 4.33Å; W655-Y708 HydrophobicContact CH2-CE2 4.36Å; W655-Y708 AromaticContact CZ2-CD2 3.7Å; W655-Y708 HydrophobicContact CZ2-CD2 3.7Å; W655-Y708 AromaticContact CZ2-CE2 3.75Å; W655-Y708 HydrophobicContact CZ2-CE2 3.75Å; Y705-Y708 VanDerWaalsContact CB-CD2 3.43Å; Y705-Y708 VanDerWaalsContact CB-CG 3.44Å; Y705-Y708 HydrophobicContact CD1-CD1 4.28Å; Y705-Y708 AromaticContact CD1-CE1 3.59Å; Y705-Y708 HydrophobicContact CD1-CE1 3.59Å; Y705-Y708 HydrophobicContact CD1-CE2 4.13Å; Y705-Y708 AromaticContact CD1-CZ 3.49Å; Y705-Y708 VanDerWaalsContact CD1-CZ 3.49Å; Y705-Y708 HydrophobicContact CD2-CD2 4.25Å; Y705-Y708 AromaticContact CD2-CE2 3.59Å; Y705-Y708 HydrophobicContact CD2-CE2 3.59Å; Y705-Y708 AromaticContact CD2-CZ 3.77Å; Y705-Y708 HydrophobicContact CE1-CE1 4.33Å; Y705-Y708 AromaticContact CE1-CZ 3.99Å; Y705-Y708 HydrophobicContact CE2-CE2 4.29Å; Y705-Y708 HydrophobicContact CG-CD1 4.13Å; Y705-Y708 AromaticContact CG-CD2 3.96Å; Y705-Y708 HydrophobicContact CG-CD2 3.96Å; Y705-Y708 AromaticContact CG-CE1 3.72Å; Y705-Y708 HydrophobicContact CG-CE1 3.72Å; Y705-Y708 AromaticContact CG-CE2 3.5Å; Y705-Y708 HydrophobicContact CG-CE2 3.5Å; Y705-Y708 HydrophobicContact CG-CG 4.25Å; Y705-Y708 AromaticContact CG-CZ 3.37Å; Y705-Y708 WeakPolarHBondContact O-CB 3.31Å; Y705-Y708 PolarHBondContact O-N 3.39Å; Y705-Y708 VanDerWaalsContact O-N 3.16Å; T706-Y708 VanDerWaalsContact C-N 3.28Å; T706-Y708 PolarHBondContact O-N 3.1Å; Y708-N710 PolarHBondContact O-N 3.36Å; Y708-F712 AromaticContact CD1-CD2 3.97Å; Y708-F712 HydrophobicContact CD1-CD2 3.97Å; Y708-F712 AromaticContact CD1-CE2 3.47Å; Y708-F712 HydrophobicContact CD1-CE2 3.47Å; Y708-F712 VanDerWaalsContact CD1-CE2 3.47Å; Y708-F712 HydrophobicContact CD2-CD2 4.11Å; Y708-F712 AromaticContact CD2-CE2 3.64Å; Y708-F712 HydrophobicContact CD2-CE2 3.64Å; Y708-F712 AromaticContact CE1-CE2 3.71Å; Y708-F712 HydrophobicContact CE1-CE2 3.71Å; Y708-F712 HydrophobicContact CE1-CZ 4.42Å; Y708-F712 AromaticContact CE2-CE2 3.88Å; Y708-F712 HydrophobicContact CE2-CE2 3.88Å; Y708-F712 AromaticContact CG-CD2 3.68Å; Y708-F712 HydrophobicContact CG-CD2 3.68Å; Y708-F712 AromaticContact CG-CE2 3.43Å; Y708-F712 HydrophobicContact CG-CE2 3.43Å; Y708-F712 VanDerWaalsContact CG-CE2 3.43Å; Y708-F712 AromaticContact CZ-CE2 3.91Å; Y708-F712 WeakPolarHBondContact O-CB 3.45Å; Y708-F712 PolarHBondContact O-N 2.9Å; Y708-F712 VanDerWaalsContact O-N 3.13Å; Y708-P713 WeakPolarHBondContact O-CD 3.47Å
709R98.8Very high98.8Very high37 Ų376.9 Ų6.914%0.143%0.033CC..Hα-helixtrans-68.1-14.6177.973.5-177.6-174.1-90.6-9.1113.7H55 D687 W688 T706 S707 P713H55-R709 PolarHBondContact CE1-NH2 2.8Å; D687-R709 IonicContact OD1-NE 2.84Å; W688-R709 HydrophobicContact CB-CB 4.45Å; W688-R709 VanDerWaalsContact CB-O 3.28Å; W688-R709 WeakPolarHBondContact CB-O 3.37Å; W688-R709 VanDerWaalsContact O-CD 3.29Å; W688-R709 WeakPolarHBondContact O-CD 3.32Å; W688-R709 PolarHBondContact O-NE 3.25Å; T706-R709 PolarHBondContact O-NH1 2.68Å; S707-R709 VanDerWaalsContact C-N 3.32Å; S707-R709 PolarHBondContact O-N 3.13Å; R709-P713 WeakPolarHBondContact O-CD 3.41Å; R709-P713 VanDerWaalsContact O-CG 3.22Å; R709-P713 WeakPolarHBondContact O-CG 3.37Å
710N98.9Very high98.8Very high2 Ų26.2 Ų6.21%0.0113%0.03CC..Hα-helixtrans-104-51.1175.5-79.7-83.5000111.2Y85 D687 S707 Y708 F712 P713 I714Y85-N710 HydrophobicContact CD1-CB 4.44Å; Y85-N710 HydrophobicContact CD2-CB 3.37Å; Y85-N710 HydrophobicContact CE2-CB 3.64Å; Y85-N710 HydrophobicContact CG-CB 3.83Å; D687-N710 PolarHBondContact OD1-ND2 2.86Å; D687-N710 PolarHBondContact OD1-OD1 3Å; D687-N710 VanDerWaalsContact OD1-OD1 3.09Å; S707-N710 PolarHBondContact O-N 2.78Å; Y708-N710 PolarHBondContact O-N 3.36Å; N710-F712 PolarHBondContact O-N 2.74Å; N710-P713 WeakPolarHBondContact O-CD 2.97Å; N710-I714 WeakPolarHBondContact O-CD1 3.46Å; N710-I714 WeakPolarHBondContact O-CG1 3.42Å; N710-I714 PolarHBondContact O-N 3.39Å
711V98.9Very high98.8Very high1 Ų17 Ų71%0.0064%0.036CC..Hα-helixtrans-61.4-47.7-175.3171.50000111.5Y85 F392 A393 A396 S707 I714 W715Y85-V711 HydrophobicContact CE1-CG2 3.66Å; F392-V711 HydrophobicContact CB-CG1 3.69Å; A393-V711 HydrophobicContact CB-CG2 4.14Å; A396-V711 HydrophobicContact CB-CG1 3.93Å; A396-V711 WeakPolarHBondContact CB-O 3.49Å; S707-V711 WeakPolarHBondContact O-CB 3.31Å; S707-V711 WeakPolarHBondContact O-CG2 3.46Å; S707-V711 PolarHBondContact O-N 2.89Å; V711-I714 PolarHBondContact O-N 3.44Å; V711-W715 HydrophobicContact CG1-CE3 4.37Å; V711-W715 WeakPolarHBondContact O-CB 3.3Å; V711-W715 PolarHBondContact O-N 2.93Å
712F98.9Very high98.7Very high0 Ų012.6 Ų12.60%06%0.057CC..Hα-helixtrans-72.6-38.6-174.8-76.4-65.1000114.2F392 W591 C654 W655 L658 Y708 N710 W715 T716F392-F712 HydrophobicContact CD2-CZ 4.35Å; F392-F712 HydrophobicContact CE2-CZ 4.27Å; W591-F712 AromaticContact CH2-CE1 3.46Å; W591-F712 HydrophobicContact CH2-CE1 3.46Å; W591-F712 VanDerWaalsContact CH2-CE1 3.46Å; W591-F712 AromaticContact CH2-CZ 3.93Å; W591-F712 HydrophobicContact CH2-CZ 3.93Å; W591-F712 HydrophobicContact CZ2-CE1 4.18Å; W591-F712 AromaticContact CZ3-CE1 3.63Å; W591-F712 HydrophobicContact CZ3-CE1 3.63Å; W591-F712 AromaticContact CZ3-CZ 3.81Å; W591-F712 HydrophobicContact CZ3-CZ 3.81Å; C654-F712 HydrophobicContact CB-CB 3.6Å; C654-F712 HydrophobicContact CB-CG 4.42Å; W655-F712 AromaticContact CD1-CD1 3.82Å; W655-F712 AromaticContact CD1-CE1 3.71Å; W655-F712 AromaticContact CE2-CE2 3.98Å; W655-F712 HydrophobicContact CZ2-CD2 4.48Å; W655-F712 HydrophobicContact CZ2-CE2 4.05Å; W655-F712 AromaticContact NE1-CD1 3.57Å; W655-F712 AromaticContact NE1-CD2 3.57Å; W655-F712 AromaticContact NE1-CE1 3.31Å; W655-F712 VanDerWaalsContact NE1-CE1 3.31Å; W655-F712 AromaticContact NE1-CE2 3.28Å; W655-F712 VanDerWaalsContact NE1-CE2 3.28Å; W655-F712 AromaticContact NE1-CG 3.71Å; W655-F712 AromaticContact NE1-CZ 3.17Å; L658-F712 HydrophobicContact CD1-CD1 3.8Å; L658-F712 HydrophobicContact CD1-CE1 4.25Å; Y708-F712 AromaticContact CD1-CD2 3.97Å; Y708-F712 HydrophobicContact CD1-CD2 3.97Å; Y708-F712 AromaticContact CD1-CE2 3.47Å; Y708-F712 HydrophobicContact CD1-CE2 3.47Å; Y708-F712 VanDerWaalsContact CD1-CE2 3.47Å; Y708-F712 HydrophobicContact CD2-CD2 4.11Å; Y708-F712 AromaticContact CD2-CE2 3.64Å; Y708-F712 HydrophobicContact CD2-CE2 3.64Å; Y708-F712 AromaticContact CE1-CE2 3.71Å; Y708-F712 HydrophobicContact CE1-CE2 3.71Å; Y708-F712 HydrophobicContact CE1-CZ 4.42Å; Y708-F712 AromaticContact CE2-CE2 3.88Å; Y708-F712 HydrophobicContact CE2-CE2 3.88Å; Y708-F712 AromaticContact CG-CD2 3.68Å; Y708-F712 HydrophobicContact CG-CD2 3.68Å; Y708-F712 AromaticContact CG-CE2 3.43Å; Y708-F712 HydrophobicContact CG-CE2 3.43Å; Y708-F712 VanDerWaalsContact CG-CE2 3.43Å; Y708-F712 AromaticContact CZ-CE2 3.91Å; Y708-F712 WeakPolarHBondContact O-CB 3.45Å; Y708-F712 PolarHBondContact O-N 2.9Å; Y708-F712 VanDerWaalsContact O-N 3.13Å; N710-F712 PolarHBondContact O-N 2.74Å; F712-W715 HydrophobicContact CD1-CE3 4.32Å; F712-W715 HydrophobicContact CE1-CE3 4.2Å; F712-W715 HydrophobicContact CE1-CZ3 4.37Å; F712-W715 PolarHBondContact O-N 2.99Å; F712-T716 VanDerWaalsContact O-CB 3.28Å; F712-T716 WeakPolarHBondContact O-CB 3.39Å; F712-T716 PolarHBondContact O-N 2.85Å; F712-T716 PolarHBondContact O-OG1 3.18Å
713P98.9Very high98.6Very high0 Ų015 Ų150%07%0.069CC..Hα-helixtrans-60.4-46.7170.1-32.541.4000113I650 W688 Y708 R709 N710 W715 T716 L717I650-P713 HydrophobicContact CG2-CG 3.36Å; W688-P713 HydrophobicContact CD2-CB 3.9Å; W688-P713 HydrophobicContact CD2-CG 4.07Å; W688-P713 HydrophobicContact CE3-CB 4.14Å; W688-P713 HydrophobicContact CE3-CG 4.46Å; W688-P713 HydrophobicContact CG-CG 4.3Å; W688-P713 HydrophobicContact CH2-CB 3.89Å; W688-P713 HydrophobicContact CZ2-CB 3.65Å; W688-P713 HydrophobicContact CZ3-CB 4.13Å; Y708-P713 WeakPolarHBondContact O-CD 3.47Å; R709-P713 WeakPolarHBondContact O-CD 3.41Å; R709-P713 VanDerWaalsContact O-CG 3.22Å; R709-P713 WeakPolarHBondContact O-CG 3.37Å; N710-P713 WeakPolarHBondContact O-CD 2.97Å; P713-W715 VanDerWaalsContact C-N 3.3Å; P713-W715 PolarHBondContact O-N 3.39Å; P713-T716 PolarHBondContact O-N 3.31Å; P713-L717 VanDerWaalsContact O-CB 3.27Å; P713-L717 WeakPolarHBondContact O-CB 3.47Å; P713-L717 WeakPolarHBondContact O-CD1 3.48Å; P713-L717 WeakPolarHBondContact O-CG 2.98Å; P713-L717 PolarHBondContact O-N 2.98Å
714I98.9Very high98.5Very high0 Ų016.1 Ų16.10%07%0.073CC..Hα-helixtrans-56.5-48177.1-67.8165.9000110.1G81 M82 A396 F397 A400 W688 N710 V711 G718G81-I714 VanDerWaalsContact C-CD1 3.48Å; M82-I714 HydrophobicContact CG-CD1 4.29Å; M82-I714 HydrophobicContact CG-CG1 4.46Å; M82-I714 HydrophobicContact CG-CG2 3.6Å; M82-I714 HydrophobicContact SD-CG2 4.33Å; A396-I714 HydrophobicContact CB-CB 4.42Å; A396-I714 HydrophobicContact CB-CG2 4.16Å; F397-I714 HydrophobicContact CD1-CG2 4.23Å; F397-I714 HydrophobicContact CE1-CD1 3.91Å; A400-I714 HydrophobicContact CB-CG2 3.78Å; W688-I714 HydrophobicContact CZ3-CG1 4.28Å; N710-I714 WeakPolarHBondContact O-CD1 3.46Å; N710-I714 WeakPolarHBondContact O-CG1 3.42Å; N710-I714 PolarHBondContact O-N 3.39Å; V711-I714 PolarHBondContact O-N 3.44Å; I714-G718 PolarHBondContact O-N 2.82Å
715W98.9Very high98.3Very high5 Ų519.2 Ų19.22%0.0199%0.093CC..Hα-helixtrans-60.5-50.4179.3-158-23.2000111.9F392 Q395 A396 E399 L658 V711 F712 P713 G718 R719F392-W715 HydrophobicContact CB-CZ3 3.99Å; F392-W715 AromaticContact CD1-CH2 3.83Å; F392-W715 HydrophobicContact CD1-CH2 3.83Å; F392-W715 AromaticContact CD1-CZ3 3.53Å; F392-W715 HydrophobicContact CD1-CZ3 3.53Å; F392-W715 HydrophobicContact CE1-CH2 4.21Å; F392-W715 HydrophobicContact CE1-CZ3 4.14Å; F392-W715 AromaticContact CG-CZ3 3.92Å; F392-W715 HydrophobicContact CG-CZ3 3.92Å; Q395-W715 HydrophobicContact CB-CH2 3.69Å; Q395-W715 HydrophobicContact CB-CZ2 3.7Å; Q395-W715 HydrophobicContact CB-CZ3 4.2Å; Q395-W715 HydrophobicContact CG-CH2 4.41Å; A396-W715 HydrophobicContact CB-CB 3.65Å; A396-W715 HydrophobicContact CB-CD2 4.21Å; A396-W715 HydrophobicContact CB-CE3 4.2Å; A396-W715 HydrophobicContact CB-CG 4.03Å; E399-W715 VanDerWaalsContact CD-CD1 3.42Å; E399-W715 PolarHBondContact OE1-NE1 3.11Å; L658-W715 HydrophobicContact CD2-CG 4.14Å; V711-W715 HydrophobicContact CG1-CE3 4.37Å; V711-W715 WeakPolarHBondContact O-CB 3.3Å; V711-W715 PolarHBondContact O-N 2.93Å; F712-W715 HydrophobicContact CD1-CE3 4.32Å; F712-W715 HydrophobicContact CE1-CE3 4.2Å; F712-W715 HydrophobicContact CE1-CZ3 4.37Å; F712-W715 PolarHBondContact O-N 2.99Å; P713-W715 VanDerWaalsContact C-N 3.3Å; P713-W715 PolarHBondContact O-N 3.39Å; W715-G718 PolarHBondContact O-N 3.45Å; W715-R719 WeakPolarHBondContact O-CB 3.34Å; W715-R719 PolarHBondContact O-N 3.42Å
716T98.9Very high97.9Very high0 Ų023.6 Ų23.60%013%0.126CC..Hα-helixtrans-64.9-46.6-175.6-56.60000111.3C654 L657 L658 M661 L678 F712 P713 R719 F720C654-T716 VanDerWaalsContact CB-OG1 3.25Å; C654-T716 WeakPolarHBondContact CB-OG1 3.43Å; L657-T716 HydrophobicContact CB-CG2 3.57Å; L657-T716 HydrophobicContact CD1-CG2 3.71Å; L657-T716 HydrophobicContact CG-CG2 4.31Å; L658-T716 WeakPolarHBondContact CG-OG1 3.33Å; M661-T716 HydrophobicContact CE-CG2 3.78Å; L678-T716 HydrophobicContact CD1-CG2 3.88Å; F712-T716 VanDerWaalsContact O-CB 3.28Å; F712-T716 WeakPolarHBondContact O-CB 3.39Å; F712-T716 PolarHBondContact O-N 2.85Å; F712-T716 PolarHBondContact O-OG1 3.18Å; P713-T716 PolarHBondContact O-N 3.31Å; T716-R719 PolarHBondContact O-N 2.89Å; T716-F720 WeakPolarHBondContact O-CB 3.18Å; T716-F720 PolarHBondContact O-N 3.34Å
717L98.9Very high97.8Very high0 Ų022.5 Ų22.50%012%0.12CC..Hα-helixtrans-66-42.1178.9-64.5171000111A74 A77 A78 V675 L678 V679 W688 P713 F720 C721A74-L717 HydrophobicContact CB-CB 4.3Å; A74-L717 HydrophobicContact CB-CD2 3.8Å; A77-L717 HydrophobicContact CB-CD1 3.7Å; A78-L717 HydrophobicContact CB-CB 3.94Å; V675-L717 HydrophobicContact CG1-CD2 3.66Å; L678-L717 HydrophobicContact CB-CD2 4.25Å; V679-L717 HydrophobicContact CG2-CD2 4Å; W688-L717 HydrophobicContact CH2-CD1 4.29Å; W688-L717 HydrophobicContact CZ2-CD1 3.91Å; P713-L717 VanDerWaalsContact O-CB 3.27Å; P713-L717 WeakPolarHBondContact O-CB 3.47Å; P713-L717 WeakPolarHBondContact O-CD1 3.48Å; P713-L717 WeakPolarHBondContact O-CG 2.98Å; P713-L717 PolarHBondContact O-N 2.98Å; L717-F720 PolarHBondContact O-N 3.24Å; L717-C721 PolarHBondContact O-N 2.64Å; L717-C721 PolarHBondContact O-SG 2.68Å
718G98.6Very high97.4Very high3 Ų328 Ų283%0.03116%0.155CC..Hα-helixtrans-58.3-48.6173.800000112.6E399 I714 W715 F720 C721 R722E399-G718 CarbonylContact O-C 3.47Å; I714-G718 PolarHBondContact O-N 2.82Å; W715-G718 PolarHBondContact O-N 3.45Å; G718-F720 PolarHBondContact O-N 3.23Å; G718-C721 PolarHBondContact O-N 3.15Å; G718-R722 PolarHBondContact O-N 3.15Å
719R98.8Very high97.2Very high20 Ų2028.7 Ų28.78%0.07516%0.159CC..Hα-helixtrans-59-46175.9-170.2172-72.3-174.1-4.2111.9E399 E595 L658 M661 W715 T716 C721 R722 L723E399-R719 IonicContact OE1-CZ 3.61Å; E399-R719 IonicContact OE1-NE 3.99Å; E399-R719 PolarHBondContact OE1-NE 2.6Å; E399-R719 IonicContact OE1-NH2 3.54Å; E399-R719 PolarHBondContact OE1-NH2 3.26Å; E399-R719 WeakPolarHBondContact OE2-CB 3.41Å; E399-R719 WeakPolarHBondContact OE2-CG 3.38Å; E399-R719 IonicContact OE2-CZ 2.94Å; E399-R719 IonicContact OE2-NE 3.5Å; E399-R719 PolarHBondContact OE2-NE 2.99Å; E399-R719 IonicContact OE2-NH2 2.72Å; E595-R719 IonicContact OE1-CZ 3.51Å; E595-R719 IonicContact OE1-NH1 3.78Å; E595-R719 PolarHBondContact OE1-NH1 3.49Å; E595-R719 IonicContact OE1-NH2 3.07Å; E595-R719 PolarHBondContact OE1-NH2 2.84Å; E595-R719 VanDerWaalsContact OE1-NH2 3.15Å; L658-R719 HydrophobicContact CD2-CB 4.45Å; L658-R719 PolarHBondContact O-NH1 2.97Å; L658-R719 VanDerWaalsContact O-NH1 3.08Å; M661-R719 HydrophobicContact CB-CG 4.35Å; M661-R719 HydrophobicContact CE-CB 4.02Å; M661-R719 HydrophobicContact CE-CG 4.11Å; M661-R719 HydrophobicContact SD-CB 4.43Å; M661-R719 HydrophobicContact SD-CG 4.17Å; W715-R719 WeakPolarHBondContact O-CB 3.34Å; W715-R719 PolarHBondContact O-N 3.42Å; T716-R719 PolarHBondContact O-N 2.89Å; R719-C721 PolarHBondContact O-N 2.83Å; R719-R722 PolarHBondContact O-N 2.65Å; R719-L723 HydrophobicContact CG-CD1 3.79Å; R719-L723 HydrophobicContact CG-CG 4.42Å; R719-L723 WeakPolarHBondContact O-CG 3.41Å; R719-L723 PolarHBondContact O-N 2.88Å; R719-L723 VanDerWaalsContact O-N 3.13Å
720F98.8Very high96.8Very high0 Ų027 Ų270%015%0.153CC..Hα-helixtrans-58.9-48.7178.7176.5-99.9000111.6A74 M661 I671 E672 V675 T716 L717 G718 R722 L723 Y724 L729 A730A74-F720 HydrophobicContact CB-CD1 3.79Å; A74-F720 HydrophobicContact CB-CE1 4.33Å; M661-F720 HydrophobicContact CE-CB 4.36Å; M661-F720 VanDerWaalsContact SD-CA 3.6Å; M661-F720 HydrophobicContact SD-CB 3.84Å; M661-F720 HydrophobicContact SD-CD2 4.21Å; I671-F720 HydrophobicContact CG2-CD2 3.67Å; I671-F720 HydrophobicContact CG2-CE2 3.88Å; E672-F720 HydrophobicContact CG-CE2 3.94Å; E672-F720 HydrophobicContact CG-CZ 3.74Å; V675-F720 HydrophobicContact CG1-CD1 3.8Å; V675-F720 HydrophobicContact CG1-CE1 4.01Å; V675-F720 HydrophobicContact CG1-CG 4.17Å; V675-F720 HydrophobicContact CG2-CB 4.06Å; V675-F720 HydrophobicContact CG2-CD1 4.19Å; V675-F720 HydrophobicContact CG2-CD2 3.69Å; V675-F720 HydrophobicContact CG2-CE2 4.17Å; V675-F720 HydrophobicContact CG2-CG 3.7Å; T716-F720 WeakPolarHBondContact O-CB 3.18Å; T716-F720 PolarHBondContact O-N 3.34Å; L717-F720 PolarHBondContact O-N 3.24Å; G718-F720 PolarHBondContact O-N 3.23Å; F720-R722 VanDerWaalsContact C-N 3.26Å; F720-R722 PolarHBondContact O-N 3.1Å; F720-L723 PolarHBondContact O-N 3.44Å; F720-L723 VanDerWaalsContact O-N 3.15Å; F720-Y724 AromaticContact CD2-CD2 3.43Å; F720-Y724 HydrophobicContact CD2-CD2 3.43Å; F720-Y724 VanDerWaalsContact CD2-CD2 3.43Å; F720-Y724 HydrophobicContact CD2-CE2 4.05Å; F720-Y724 HydrophobicContact CD2-CG 4.23Å; F720-Y724 AromaticContact CE2-CD2 3.6Å; F720-Y724 HydrophobicContact CE2-CD2 3.6Å; F720-Y724 HydrophobicContact CE2-CE2 4.34Å; F720-Y724 AromaticContact CE2-CG 3.96Å; F720-Y724 HydrophobicContact CE2-CG 3.96Å; F720-Y724 HydrophobicContact CG-CD2 4.27Å; F720-Y724 PolarHBondContact O-N 3.17Å; F720-L729 HydrophobicContact CE1-CB 4.2Å; F720-L729 HydrophobicContact CE1-CG 4.37Å; F720-L729 HydrophobicContact CZ-CB 4.4Å; F720-A730 HydrophobicContact CD1-CB 4.46Å; F720-A730 HydrophobicContact CE1-CB 4.05Å
721C98.1Very high95.9Very high22 Ų2227.5 Ų27.515%0.14916%0.159CC..Hα-helixtrans-57.5-38178.4-70.40000113A74 L75 L717 G718 R719A74-C721 VanDerWaalsContact CB-SG 3.54Å; L75-C721 PolarHBondContact N-SG 3.15Å; L717-C721 PolarHBondContact O-N 2.64Å; L717-C721 PolarHBondContact O-SG 2.68Å; G718-C721 PolarHBondContact O-N 3.15Å; R719-C721 PolarHBondContact O-N 2.83Å
722R96.5Very high94Very high117 Ų11737.3 Ų37.344%0.44220%0.201SC..Hα-helixtrans-69.8-37.7177.9-72.2-179.3174.9-175.32.2113.4L398 E399 G718 R719 F720L398-R722 VanDerWaalsContact O-CZ 3.22Å; L398-R722 PolarHBondContact O-NH1 3.38Å; L398-R722 PolarHBondContact O-NH2 3.36Å; E399-R722 WeakPolarHBondContact O-CD 3.4Å; E399-R722 PolarHBondContact O-NE 2.99Å; E399-R722 PolarHBondContact O-NH2 3.31Å; G718-R722 PolarHBondContact O-N 3.15Å; R719-R722 PolarHBondContact O-N 2.65Å; F720-R722 VanDerWaalsContact C-N 3.26Å; F720-R722 PolarHBondContact O-N 3.1Å
723L97.2Very high91.5Very high49 Ų4942.8 Ų42.826%0.25723%0.23SC..Hα-helixtrans-86.7-30-173.7-64.3175.7000113.2M661 R719 F720 P725M661-L723 HydrophobicContact CB-CD1 3.78Å; M661-L723 HydrophobicContact CG-CD1 4.2Å; M661-L723 HydrophobicContact SD-CD1 4.2Å; R719-L723 HydrophobicContact CG-CD1 3.79Å; R719-L723 HydrophobicContact CG-CG 4.42Å; R719-L723 WeakPolarHBondContact O-CG 3.41Å; R719-L723 PolarHBondContact O-N 2.88Å; R719-L723 VanDerWaalsContact O-N 3.13Å; F720-L723 PolarHBondContact O-N 3.44Å; F720-L723 VanDerWaalsContact O-N 3.15Å; L723-P725 WeakPolarHBondContact O-CD 3.32Å
724Y96.4Very high88.6Confident29 Ų2952.9 Ų52.911%0.11427%0.274CS..  trans-126.554.2-174.9-52.5-82.8000112M661 Q668 I671 F720 S726 S727 A730M661-Y724 HydrophobicContact CG-CE2 4.1Å; M661-Y724 HydrophobicContact SD-CE2 4.09Å; Q668-Y724 HydrophobicContact CB-CE1 4.37Å; Q668-Y724 HydrophobicContact CG-CD1 3.96Å; Q668-Y724 HydrophobicContact CG-CE1 4.11Å; I671-Y724 HydrophobicContact CD1-CE2 4.38Å; I671-Y724 VanDerWaalsContact CD1-OH 3.3Å; I671-Y724 WeakPolarHBondContact CD1-OH 3.44Å; I671-Y724 HydrophobicContact CG2-CE2 4.35Å; F720-Y724 AromaticContact CD2-CD2 3.43Å; F720-Y724 HydrophobicContact CD2-CD2 3.43Å; F720-Y724 VanDerWaalsContact CD2-CD2 3.43Å; F720-Y724 HydrophobicContact CD2-CE2 4.05Å; F720-Y724 HydrophobicContact CD2-CG 4.23Å; F720-Y724 AromaticContact CE2-CD2 3.6Å; F720-Y724 HydrophobicContact CE2-CD2 3.6Å; F720-Y724 HydrophobicContact CE2-CE2 4.34Å; F720-Y724 AromaticContact CE2-CG 3.96Å; F720-Y724 HydrophobicContact CE2-CG 3.96Å; F720-Y724 HydrophobicContact CG-CD2 4.27Å; F720-Y724 PolarHBondContact O-N 3.17Å; Y724-S726 PolarHBondContact O-N 3.28Å; Y724-S727 VanDerWaalsContact O-CB 3.32Å; Y724-S727 WeakPolarHBondContact O-CB 3.37Å; Y724-S727 PolarHBondContact O-N 3.27Å; Y724-A730 VanDerWaalsContact O-CB 3.32Å; Y724-A730 WeakPolarHBondContact O-CB 3.44Å
725P94.2Very high85.3Confident72 Ų7264.2 Ų64.247%0.46833%0.333SS..THydrogen-bonded Turntrans-64.2-15.8-176.628.3-36.9000113.8L723 L733L723-P725 WeakPolarHBondContact O-CD 3.32Å; P725-L733 HydrophobicContact CB-CD1 4.19Å
726S92.3Very high84.7Confident107 Ų10767.2 Ų67.275%0.74835%0.349SS*.THydrogen-bonded Turntrans-87.8-10.3174.755.10000113.8Y724Y724-S726 PolarHBondContact O-N 3.28Å
727S94.7Very high83.9Confident4 Ų470.7 Ų70.73%0.02837%0.367CS..SBendtrans-66.2134.4175.4176.40000109.7E672 Y724 L729 A730E672-S727 VanDerWaalsContact OE1-CB 3.28Å; E672-S727 WeakPolarHBondContact OE1-CB 3.26Å; E672-S727 PolarHBondContact OE1-OG 3.26Å; Y724-S727 VanDerWaalsContact O-CB 3.32Å; Y724-S727 WeakPolarHBondContact O-CB 3.37Å; Y724-S727 PolarHBondContact O-N 3.27Å; S727-L729 PolarHBondContact O-N 2.87Å; S727-L729 VanDerWaalsContact O-N 3.15Å; S727-L729 PolarHBondContact OG-N 3.06Å; S727-A730 WeakPolarHBondContact O-CB 3.42Å; S727-A730 PolarHBondContact O-N 3.03Å; S727-A730 VanDerWaalsContact O-N 3.09Å
728P90.9Very high83.1Confident118 Ų11874.7 Ų74.777%0.76639%0.388SS*.THydrogen-bonded Turntrans-60.4-24.5173.526.9-34.4000112.1
729L94.1Very high82.2Confident16 Ų1678.9 Ų78.98%0.08441%0.409CS..THydrogen-bonded Turntrans-78.8-21.5178.9-170.560.5000113.1T73 A74 E672 V675 Q676 F720 S727 G731T73-L729 CarbonylContact C-O 3.54Å; T73-L729 WeakPolarHBondContact CA-O 3.42Å; T73-L729 WeakPolarHBondContact CB-O 3.28Å; A74-L729 PolarHBondContact N-O 3.4Å; E672-L729 HydrophobicContact CB-CD2 4.19Å; E672-L729 HydrophobicContact CG-CD2 4.4Å; E672-L729 VanDerWaalsContact O-CD2 3.28Å; E672-L729 WeakPolarHBondContact O-CD2 3.32Å; V675-L729 HydrophobicContact CB-CD2 3.85Å; V675-L729 HydrophobicContact CG1-CD2 3.63Å; V675-L729 HydrophobicContact CG1-CG 4Å; Q676-L729 HydrophobicContact CB-CD2 4.08Å; Q676-L729 VanDerWaalsContact OE1-CD1 3.23Å; F720-L729 HydrophobicContact CE1-CB 4.2Å; F720-L729 HydrophobicContact CE1-CG 4.37Å; F720-L729 HydrophobicContact CZ-CB 4.4Å; S727-L729 PolarHBondContact O-N 2.87Å; S727-L729 VanDerWaalsContact O-N 3.15Å; S727-L729 PolarHBondContact OG-N 3.06Å; L729-G731 VanDerWaalsContact C-N 3.3Å; L729-G731 PolarHBondContact O-N 3Å
730A92Very high81.1Confident3 Ų382.6 Ų82.63%0.02543%0.43CS..THydrogen-bonded Turntrans-67.1-35.8176.300000111.3L75 F720 Y724 S727L75-A730 WeakPolarHBondContact CB-O 3.2Å; L75-A730 PolarHBondContact N-O 3.47Å; L75-A730 VanDerWaalsContact N-O 3.12Å; F720-A730 HydrophobicContact CD1-CB 4.46Å; F720-A730 HydrophobicContact CE1-CB 4.05Å; Y724-A730 VanDerWaalsContact O-CB 3.32Å; Y724-A730 WeakPolarHBondContact O-CB 3.44Å; S727-A730 WeakPolarHBondContact O-CB 3.42Å; S727-A730 PolarHBondContact O-N 3.03Å; S727-A730 VanDerWaalsContact O-N 3.09Å
731G79.8Confident79.9Confident12 Ų1288.1 Ų88.112%0.12446%0.458CS..  trans101.5150.4-173.700000112L729 L733L729-G731 VanDerWaalsContact C-N 3.3Å; L729-G731 PolarHBondContact O-N 3Å; G731-L733 PolarHBondContact O-N 2.86Å; G731-L733 VanDerWaalsContact O-N 3.12Å
732K59Low78.6Confident206 Ų20692.8 Ų92.890%0.89648%0.48SS*.  trans-71.5107.5176-73.2-176179.7178.80109.2K734K732-K734 PolarHBondContact O-N 2.77Å; K732-K734 VanDerWaalsContact O-N 3.15Å
733L45.9Very low77.3Confident116 Ų11690.9 Ų90.961%0.60748%0.483SS*.  trans-50.1120.5155.5-84.5158.1000106.8P725 G731 L735P725-L733 HydrophobicContact CB-CD1 4.19Å; G731-L733 PolarHBondContact O-N 2.86Å; G731-L733 VanDerWaalsContact O-N 3.12Å; L733-L735 VanDerWaalsContact C-N 3.25Å; L733-L735 PolarHBondContact O-N 3.19Å
734K36.8Very low75.6Confident212 Ų21294.4 Ų94.492%0.92250%0.502SS*.  trans-62.799.4163.5-82.1-177.2175.8177.90105.8K732K732-K734 PolarHBondContact O-N 2.77Å; K732-K734 VanDerWaalsContact O-N 3.15Å
735L31.3Very low73.7Confident238 Ų238100.4 Ų100.4100%1.24654%0.538SS*.  trans-590168.2-87161.7000110.2L733L733-L735 VanDerWaalsContact C-N 3.25Å; L733-L735 PolarHBondContact O-N 3.19Å

Retrieved 735 of 735 residues in 1463.3 ms (Link to these results)