A0A087Y490_POEFO Loading...

Amine oxidase

AlphaFold DB , UniProt , Accession A0A087Y490, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 742 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M44.8Very low40.2Very low222 Ų222128.5 Ų128.5100%1.09469%0.688SS**  0-260-91.9170.970.200115.7
2K42.3Very low40Very low196 Ų196128.1 Ų128.185%0.85269%0.685SS**Hα-helixtrans-80.5-15.3-179.9-78.1-177.6175.6178.80116.3
3V42.7Very low39.8Very low111 Ų111126.3 Ų126.367%0.67368%0.681SS**Hα-helixtrans-86.4-27.6-178.5-179.50000112.7L7V3-L7 HydrophobicContact CG1-CD1 4.42Å
4L37.7Very low39.1Very low135 Ų135120.3 Ų120.371%0.70766%0.664SS**Hα-helixtrans-71.7-31178.1-111.684.7000113.4Q8L4-Q8 PolarHBondContact O-N 3.08Å
5C40Very low38.9Very low85 Ų85121.6 Ų121.657%0.57466%0.66SS**Hα-helixtrans-71.7-29.4177.9-83.20000113.5L9C5-L9 PolarHBondContact O-N 2.74Å
6M39Very low39.3Very low155 Ų155118.8 Ų118.876%0.76465%0.653SS**Hα-helixtrans-75.6-33.1176.8-82.7-153.7-176.100112.6L9 A10M6-L9 PolarHBondContact O-N 2.91Å; M6-A10 PolarHBondContact O-N 3.3Å; M6-A10 VanDerWaalsContact O-N 3.1Å
7L39.1Very low39.5Very low115 Ų115114.9 Ų114.960%0.60264%0.64SS**Hα-helixtrans-68.8-35.6173.9-97.1108000112.5V3 A10 C11V3-L7 HydrophobicContact CG1-CD1 4.42Å; L7-A10 PolarHBondContact O-N 2.72Å; L7-C11 WeakPolarHBondContact O-CB 3.49Å; L7-C11 PolarHBondContact O-N 3.03Å; L7-C11 PolarHBondContact O-SG 2.89Å
8Q38.8Very low40Very low129 Ų129111.4 Ų111.460%0.60363%0.628SS**Hα-helixtrans-68.7-33.6175.2-78.7-174.8-29.100112.9L4 L12L4-Q8 PolarHBondContact O-N 3.08Å; Q8-L12 WeakPolarHBondContact O-CG 3.34Å; Q8-L12 PolarHBondContact O-N 2.83Å; Q8-L12 VanDerWaalsContact O-N 3.11Å
9L41.7Very low40.5Very low126 Ų126113.6 Ų113.666%0.6663%0.625SS**Hα-helixtrans-71-39.4174.8-121.483.7000112.4C5 M6 L12 V13C5-L9 PolarHBondContact O-N 2.74Å; M6-L9 PolarHBondContact O-N 2.91Å; L9-L12 PolarHBondContact O-N 2.73Å; L9-V13 WeakPolarHBondContact O-CG2 3.46Å; L9-V13 PolarHBondContact O-N 2.99Å
10A38.2Very low41.1Very low69 Ų69109.7 Ų109.757%0.5761%0.605SS**Hα-helixtrans-67.2-36.7175.200000112.2M6 L7 G14M6-A10 PolarHBondContact O-N 3.3Å; M6-A10 VanDerWaalsContact O-N 3.1Å; L7-A10 PolarHBondContact O-N 2.72Å; A10-G14 PolarHBondContact O-N 3.31Å
11C37.5Very low41.7Very low70 Ų70113.1 Ų113.147%0.47361%0.609SS.*Hα-helixtrans-65.9-41173.9-74.80000112.4L7 V13 G14 F15L7-C11 WeakPolarHBondContact O-CB 3.49Å; L7-C11 PolarHBondContact O-N 3.03Å; L7-C11 PolarHBondContact O-SG 2.89Å; C11-V13 PolarHBondContact O-N 3.42Å; C11-G14 PolarHBondContact O-N 3.46Å; C11-F15 VanDerWaalsContact O-CD2 3.28Å; C11-F15 WeakPolarHBondContact O-CD2 3.18Å; C11-F15 PolarHBondContact O-N 3.13Å
12L37.8Very low42.6Very low124 Ų124108.2 Ų108.265%0.64958%0.584SS**Hα-helixtrans-65.7-36.7179.5-81.2160.4000113.2Q8 L9 S16Q8-L12 WeakPolarHBondContact O-CG 3.34Å; Q8-L12 PolarHBondContact O-N 2.83Å; Q8-L12 VanDerWaalsContact O-N 3.11Å; L9-L12 PolarHBondContact O-N 2.73Å; L12-S16 PolarHBondContact O-N 3.08Å
13V37.4Very low43.8Very low105 Ų105102.6 Ų102.664%0.63656%0.557SS**Hα-helixtrans-72.2-37.1174.3-179.50000111L9 C11 S16 A17L9-V13 WeakPolarHBondContact O-CG2 3.46Å; L9-V13 PolarHBondContact O-N 2.99Å; C11-V13 PolarHBondContact O-N 3.42Å; V13-S16 PolarHBondContact O-N 3.16Å; V13-A17 PolarHBondContact O-N 3.36Å
14G30.9Very low44.7Very low42 Ų4297.5 Ų97.543%0.43353%0.527SS..Hα-helixtrans-64.2-37.2173.100000113.8A10 C11 A18A10-G14 PolarHBondContact O-N 3.31Å; C11-G14 PolarHBondContact O-N 3.46Å; G14-A18 WeakPolarHBondContact O-CB 3.5Å; G14-A18 PolarHBondContact O-N 3.34Å
15F36.2Very low46.1Very low140 Ų14096 Ų9661%0.61452%0.516SS*.Hα-helixtrans-69.8-32.2176.8-96.1-80.3000113.2C11 R19C11-F15 VanDerWaalsContact O-CD2 3.28Å; C11-F15 WeakPolarHBondContact O-CD2 3.18Å; C11-F15 PolarHBondContact O-N 3.13Å; F15-R19 WeakPolarHBondContact O-CB 3.03Å; F15-R19 WeakPolarHBondContact O-CG 3.44Å; F15-R19 PolarHBondContact O-N 3.43Å
16S44.7Very low47.7Very low77 Ų7797.6 Ų97.654%0.53852%0.515SS..Hα-helixtrans-69.7-46.3175.7153.60000111.9L12 V13 A18 R19 T20L12-S16 PolarHBondContact O-N 3.08Å; V13-S16 PolarHBondContact O-N 3.16Å; S16-A18 VanDerWaalsContact C-N 3.34Å; S16-R19 PolarHBondContact O-N 3.46Å; S16-T20 PolarHBondContact O-N 3.12Å; S16-T20 VanDerWaalsContact O-N 3.14Å; S16-T20 PolarHBondContact O-OG1 2.88Å
17A43.1Very low49.8Very low53 Ų5390.4 Ų90.444%0.43848%0.48SS..Hα-helixtrans-70.1-29.2176.800000112.9V13 T20 R21V13-A17 PolarHBondContact O-N 3.36Å; A17-T20 WeakPolarHBondContact CA-OG1 3.42Å; A17-T20 PolarHBondContact O-OG1 2.67Å; A17-T20 VanDerWaalsContact O-OG1 3.09Å; A17-R21 PolarHBondContact O-N 3.39Å
18A47.3Very low52.2Low52 Ų5285.2 Ų85.243%0.4345%0.454SS..Hα-helixtrans-69.8-40.7172.600000112G14 S16 R21 E22G14-A18 WeakPolarHBondContact O-CB 3.5Å; G14-A18 PolarHBondContact O-N 3.34Å; S16-A18 VanDerWaalsContact C-N 3.34Å; A18-R21 PolarHBondContact O-N 3.26Å; A18-E22 PolarHBondContact O-N 3.47Å; A18-E22 VanDerWaalsContact O-N 3.08Å
19R51.1Low54.8Low152 Ų15280.5 Ų80.557%0.57443%0.434SS*.Hα-helixtrans-67.7-37.6176.8-81.8-177.5175-175.5-0.9113.5F15 S16 E22 W23F15-R19 WeakPolarHBondContact O-CB 3.03Å; F15-R19 WeakPolarHBondContact O-CG 3.44Å; F15-R19 PolarHBondContact O-N 3.43Å; S16-R19 PolarHBondContact O-N 3.46Å; R19-E22 WeakPolarHBondContact O-CB 3.27Å; R19-E22 PolarHBondContact O-N 3.08Å; R19-W23 HydrophobicContact CB-CE3 4.34Å; R19-W23 HydrophobicContact CB-CZ3 3.95Å; R19-W23 PolarHBondContact O-N 2.61Å
20T51.5Low57.3Low36 Ų3675.1 Ų75.122%0.22141%0.406CS..Hα-helixtrans-64.7-37.8175.947.20000112.8S16 A17 W23 A24 E307S16-T20 PolarHBondContact O-N 3.12Å; S16-T20 VanDerWaalsContact O-N 3.14Å; S16-T20 PolarHBondContact O-OG1 2.88Å; A17-T20 WeakPolarHBondContact CA-OG1 3.42Å; A17-T20 PolarHBondContact O-OG1 2.67Å; A17-T20 VanDerWaalsContact O-OG1 3.09Å; T20-W23 WeakPolarHBondContact O-CB 3.22Å; T20-W23 PolarHBondContact O-N 3.41Å; T20-A24 PolarHBondContact O-N 3.39Å; T20-A24 VanDerWaalsContact O-N 3.15Å; T20-E307 WeakPolarHBondContact CB-OE1 3.43Å; T20-E307 WeakPolarHBondContact CG2-OE1 3.48Å
21R54.9Low60.2Low181 Ų18171.9 Ų71.968%0.68338%0.379SS*.Hα-helixtrans-69.5-31.8172.2-71.7-175.3176.2-165-1.8113.5A17 A18 W23 A24 H25A17-R21 PolarHBondContact O-N 3.39Å; A18-R21 PolarHBondContact O-N 3.26Å; R21-W23 VanDerWaalsContact C-N 3.31Å; R21-A24 PolarHBondContact O-N 2.92Å; R21-H25 PolarHBondContact O-CD2 2.94Å; R21-H25 VanDerWaalsContact O-CD2 3.29Å; R21-H25 PolarHBondContact O-N 3.48Å
22E63.6Low63Low120 Ų12069.5 Ų69.556%0.56137%0.365SS*.Hα-helixtrans-61.4-40.2168.2-77.3-178.616400111.2A18 R19 H25 H26A18-E22 PolarHBondContact O-N 3.47Å; A18-E22 VanDerWaalsContact O-N 3.08Å; R19-E22 WeakPolarHBondContact O-CB 3.27Å; R19-E22 PolarHBondContact O-N 3.08Å; E22-H25 PolarHBondContact O-N 2.03Å; E22-H26 WeakPolarHBondContact O-CA 3.42Å; E22-H26 VanDerWaalsContact O-CB 3.23Å; E22-H26 WeakPolarHBondContact O-CB 3.43Å; E22-H26 PolarHBondContact O-CD2 3.26Å; E22-H26 PolarHBondContact O-N 2.97Å
23W66.4Low65.9Low77 Ų7765.3 Ų65.329%0.29234%0.343SS..Hα-helixtrans-63.3-40.6176.3-92.8-63.6000113.5R19 T20 R21 H25 G27 A28 L84R19-W23 HydrophobicContact CB-CE3 4.34Å; R19-W23 HydrophobicContact CB-CZ3 3.95Å; R19-W23 PolarHBondContact O-N 2.61Å; T20-W23 WeakPolarHBondContact O-CB 3.22Å; T20-W23 PolarHBondContact O-N 3.41Å; R21-W23 VanDerWaalsContact C-N 3.31Å; W23-H25 VanDerWaalsContact C-N 3.28Å; W23-H25 PolarHBondContact O-N 3.49Å; W23-G27 WeakPolarHBondContact O-CA 3.29Å; W23-G27 PolarHBondContact O-N 3.48Å; W23-A28 PolarHBondContact O-N 2.95Å; W23-L84 PolarHBondContact NE1-O 3.23Å
24A62Low68.8Low5 Ų560.8 Ų60.84%0.04132%0.315CS..Hα-helixtrans-58-39.2175.800000112.5T20 R21 P29 D302 F305T20-A24 PolarHBondContact O-N 3.39Å; T20-A24 VanDerWaalsContact O-N 3.15Å; R21-A24 PolarHBondContact O-N 2.92Å; A24-P29 WeakPolarHBondContact O-CD 3.18Å; A24-D302 HydrophobicContact CB-CB 4.22Å; A24-F305 HydrophobicContact CB-CB 4.26Å; A24-F305 HydrophobicContact CB-CD1 3.36Å; A24-F305 HydrophobicContact CB-CE1 3.81Å; A24-F305 HydrophobicContact CB-CG 3.97Å
25H65.9Low72Confident103 Ų10362 Ų6248%0.47731%0.314SS..Hα-helixtrans-93.2-28.2-177.5-63.7-44.6000114.2R21 E22 W23 K90 D302R21-H25 PolarHBondContact O-CD2 2.94Å; R21-H25 VanDerWaalsContact O-CD2 3.29Å; R21-H25 PolarHBondContact O-N 3.48Å; E22-H25 PolarHBondContact O-N 2.03Å; W23-H25 VanDerWaalsContact C-N 3.28Å; W23-H25 PolarHBondContact O-N 3.49Å; H25-K90 PolarHBondContact O-NZ 2.96Å; H25-D302 IonicContact CE1-OD2 3.92Å; H25-D302 PolarHBondContact CE1-OD2 3.08Å; H25-D302 IonicContact ND1-OD2 2.92Å; H25-D302 PolarHBondContact ND1-OD2 3.4Å; H25-D302 VanDerWaalsContact ND1-OD2 3.1Å; H25-D302 IonicContact NE2-OD2 2.71Å
26H74.5Confident75Confident119 Ų11956.8 Ų56.855%0.55129%0.293SS*.Hα-helixtrans-98.5-46.6-177.5-73.1-86.6000113.3E22 K90E22-H26 WeakPolarHBondContact O-CA 3.42Å; E22-H26 VanDerWaalsContact O-CB 3.23Å; E22-H26 WeakPolarHBondContact O-CB 3.43Å; E22-H26 PolarHBondContact O-CD2 3.26Å; E22-H26 PolarHBondContact O-N 2.97Å; H26-K90 VanDerWaalsContact O-CD 3.23Å; H26-K90 WeakPolarHBondContact O-CD 3.4Å; H26-K90 WeakPolarHBondContact O-CE 3.35Å; H26-K90 PolarHBondContact O-NZ 3.39Å
27G84.2Confident77.6Confident3 Ų360.7 Ų60.73%0.03130%0.303CS..THydrogen-bonded Turntrans-86.7-63.5-171.700000114W23 P29 M30W23-G27 WeakPolarHBondContact O-CA 3.29Å; W23-G27 PolarHBondContact O-N 3.48Å; G27-P29 VanDerWaalsContact C-N 3.33Å; G27-M30 WeakPolarHBondContact O-CB 3.47Å; G27-M30 WeakPolarHBondContact O-CE 3.43Å; G27-M30 WeakPolarHBondContact O-CG 3.34Å; G27-M30 PolarHBondContact O-N 3.23Å; G27-M30 VanDerWaalsContact O-N 3.08Å
28A88.8Confident80.2Confident6 Ų658.9 Ų58.95%0.0529%0.286CS..G310 helixtrans-53.9-36.3-172.500000115.5W23 M30 F31 A32 N304 F305 A314W23-A28 PolarHBondContact O-N 2.95Å; A28-M30 PolarHBondContact O-N 3.4Å; A28-M30 VanDerWaalsContact O-N 3.08Å; A28-F31 PolarHBondContact O-N 3.5Å; A28-A32 PolarHBondContact O-N 3.27Å; A28-N304 PolarHBondContact O-ND2 3.31Å; A28-N304 PolarHBondContact O-OD1 2.66Å; A28-F305 HydrophobicContact CB-CB 3.61Å; A28-F305 HydrophobicContact CB-CD2 3.93Å; A28-F305 HydrophobicContact CB-CG 4.12Å; A28-A314 HydrophobicContact CB-CB 3.76Å
29P92.9Very high82.6Confident31 Ų3156.5 Ų56.520%0.20127%0.266CS..G310 helixtrans-64.3-15.2179.7-2637.5000114.7A24 G27 F31 A32 R93A24-P29 WeakPolarHBondContact O-CD 3.18Å; G27-P29 VanDerWaalsContact C-N 3.33Å; P29-F31 PolarHBondContact O-N 2.85Å; P29-A32 PolarHBondContact O-N 3.06Å; P29-R93 PolarHBondContact O-NH1 2.93Å
30M95.1Very high84.9Confident12 Ų1253.3 Ų53.36%0.05926%0.256CS..G310 helixtrans-64.4-26.5171.5-63.1-170.8-67.600112.2G27 A28 A80 A83 L84 K90 P91G27-M30 WeakPolarHBondContact O-CB 3.47Å; G27-M30 WeakPolarHBondContact O-CE 3.43Å; G27-M30 WeakPolarHBondContact O-CG 3.34Å; G27-M30 PolarHBondContact O-N 3.23Å; G27-M30 VanDerWaalsContact O-N 3.08Å; A28-M30 PolarHBondContact O-N 3.4Å; A28-M30 VanDerWaalsContact O-N 3.08Å; M30-A80 HydrophobicContact CE-CB 4.4Å; M30-A83 HydrophobicContact CE-CB 4.02Å; M30-A83 HydrophobicContact SD-CB 3.95Å; M30-L84 HydrophobicContact CE-CD1 4.32Å; M30-L84 HydrophobicContact CE-CD2 3.64Å; M30-L84 HydrophobicContact CE-CG 3.67Å; M30-K90 HydrophobicContact CG-CB 4.29Å; M30-K90 HydrophobicContact CG-CD 4.14Å; M30-K90 HydrophobicContact CG-CG 4.31Å; M30-K90 HydrophobicContact SD-CB 4.11Å; M30-K90 HydrophobicContact SD-CG 4.28Å; M30-P91 WeakPolarHBondContact SD-CD 3.47Å; M30-P91 HydrophobicContact SD-CG 4Å
31F97.6Very high87.1Confident1 Ų153 Ų530%0.00426%0.257CS..THydrogen-bonded Turntrans-101-9.7-177.7-52.8-63.4000113.1A28 P29 L72 L74 A80 L84 A314 R316 F326 D327 Y337A28-F31 PolarHBondContact O-N 3.5Å; P29-F31 PolarHBondContact O-N 2.85Å; F31-L72 WeakPolarHBondContact O-CD2 3.24Å; F31-L74 HydrophobicContact CD1-CD2 3.89Å; F31-A80 HydrophobicContact CZ-CB 4.29Å; F31-L84 HydrophobicContact CE2-CD1 4.1Å; F31-L84 HydrophobicContact CE2-CD2 4.49Å; F31-L84 HydrophobicContact CZ-CD1 4.02Å; F31-A314 HydrophobicContact CB-CB 4.36Å; F31-A314 HydrophobicContact CD2-CB 3.94Å; F31-R316 WeakPolarHBondContact O-CB 3.5Å; F31-R316 WeakPolarHBondContact O-CD 3.48Å; F31-F326 HydrophobicContact CB-CB 4.2Å; F31-F326 HydrophobicContact CB-CD2 4.01Å; F31-F326 HydrophobicContact CB-CG 4.09Å; F31-F326 HydrophobicContact CD1-CB 4.02Å; F31-F326 AromaticContact CD1-CD1 3.68Å; F31-F326 HydrophobicContact CD1-CD1 3.68Å; F31-F326 HydrophobicContact CD1-CD2 4.31Å; F31-F326 HydrophobicContact CD1-CE1 4.23Å; F31-F326 AromaticContact CD1-CG 3.73Å; F31-F326 HydrophobicContact CD1-CG 3.73Å; F31-F326 HydrophobicContact CD2-CB 3.76Å; F31-F326 HydrophobicContact CD2-CG 4.34Å; F31-F326 HydrophobicContact CE1-CB 4.33Å; F31-F326 AromaticContact CE1-CD1 3.84Å; F31-F326 HydrophobicContact CE1-CD1 3.84Å; F31-F326 HydrophobicContact CE1-CG 4.21Å; F31-F326 HydrophobicContact CE2-CB 4.08Å; F31-F326 HydrophobicContact CG-CB 3.72Å; F31-F326 HydrophobicContact CG-CD1 4.24Å; F31-F326 HydrophobicContact CG-CD2 4.23Å; F31-F326 AromaticContact CG-CG 3.8Å; F31-F326 HydrophobicContact CG-CG 3.8Å; F31-F326 HydrophobicContact CZ-CB 4.35Å; F31-F326 HydrophobicContact CZ-CD1 4.5Å; F31-D327 HydrophobicContact CE2-CB 4.37Å; F31-Y337 HydrophobicContact CE1-CE2 4.39Å; F31-Y337 HydrophobicContact CZ-CE2 4.1Å
32A97.8Very high89.2Confident21 Ų2144.3 Ų44.317%0.17422%0.224CC..SBendtrans-65.3137.6-178.200000111.6A28 P29 L72 R93 N304A28-A32 PolarHBondContact O-N 3.27Å; P29-A32 PolarHBondContact O-N 3.06Å; A32-L72 VanDerWaalsContact O-CD2 3.3Å; A32-L72 WeakPolarHBondContact O-CD2 3.02Å; A32-R93 VanDerWaalsContact O-CZ 3.25Å; A32-R93 PolarHBondContact O-NH1 3Å; A32-R93 PolarHBondContact O-NH2 3.35Å; A32-N304 WeakPolarHBondContact CA-ND2 3.4Å; A32-N304 HydrophobicContact CB-CB 4.25Å; A32-N304 PolarHBondContact N-ND2 2.78Å
33D98.5Very high90.9Very high36 Ų3641.1 Ų41.119%0.19321%0.207CC..PPolyproline II helixtrans-55.9163.4173.9-69.8-53.4000112.6T35 R93 R316 V317D33-T35 PolarHBondContact O-N 3.45Å; D33-R93 PolarHBondContact O-NH2 3.5Å; D33-R316 IonicContact OD1-CZ 2.68Å; D33-R316 IonicContact OD1-NE 2.79Å; D33-R316 PolarHBondContact OD1-NE 3.4Å; D33-R316 IonicContact OD1-NH2 3.15Å; D33-R316 PolarHBondContact OD1-NH2 3.06Å; D33-R316 WeakPolarHBondContact OD2-CB 3.26Å; D33-V317 PolarHBondContact OD2-N 3.34Å
34L98.6Very high92.4Very high9 Ų941.3 Ų41.35%0.04722%0.22CC..PPolyproline II helixtrans-61.2136.4-179.4-62.1178.4000110.5E38 M39 I42 M70 E71 L72 A95 L117L34-E38 WeakPolarHBondContact CA-OE2 3.34Å; L34-E38 HydrophobicContact CB-CB 4.49Å; L34-E38 HydrophobicContact CD2-CB 4.46Å; L34-M39 HydrophobicContact CB-CE 4.4Å; L34-M39 HydrophobicContact CB-CG 3.82Å; L34-M39 HydrophobicContact CB-SD 4.49Å; L34-M39 HydrophobicContact CD1-CG 4.1Å; L34-M39 VanDerWaalsContact O-CE 3.29Å; L34-M39 WeakPolarHBondContact O-CE 2.96Å; L34-I42 HydrophobicContact CD1-CD1 3.88Å; L34-M70 HydrophobicContact CD1-CB 4.2Å; L34-E71 VanDerWaalsContact CD1-C 3.5Å; L34-L72 HydrophobicContact CD2-CB 4.36Å; L34-L72 HydrophobicContact CD2-CD1 4.26Å; L34-L72 HydrophobicContact CG-CB 4.38Å; L34-A95 HydrophobicContact CD1-CB 3.79Å; L34-A95 HydrophobicContact CD2-CB 4.14Å; L34-L117 HydrophobicContact CD2-CD1 3.45Å; L34-L117 VanDerWaalsContact CD2-CD1 3.45Å
35T98.2Very high94.1Very high68 Ų6843.5 Ų43.542%0.41723%0.228SC..PPolyproline II helixtrans-76.6160.2171.166.20000110.9D33 Q37 E38 M39D33-T35 PolarHBondContact O-N 3.45Å; T35-Q37 PolarHBondContact O-N 2.92Å; T35-E38 PolarHBondContact N-OE2 3.44Å; T35-E38 PolarHBondContact O-N 2.91Å; T35-E38 VanDerWaalsContact O-N 3.08Å; T35-E38 VanDerWaalsContact OG1-CG 3.25Å; T35-E38 WeakPolarHBondContact OG1-CG 3.39Å; T35-E38 PolarHBondContact OG1-N 3.36Å; T35-E38 PolarHBondContact OG1-OE2 3.08Å; T35-M39 PolarHBondContact O-N 3.43Å
36V98.4Very high95.6Very high30 Ų3038.6 Ų38.618%0.18221%0.205CC..Hα-helixtrans-53.8-40.8173.7175.90000111.6M39 K40 Y390 P398 V742V36-M39 PolarHBondContact O-N 3.01Å; V36-K40 HydrophobicContact CG1-CD 4.1Å; V36-K40 WeakPolarHBondContact O-CB 3.19Å; V36-K40 WeakPolarHBondContact O-CG 3.36Å; V36-K40 PolarHBondContact O-N 3.15Å; V36-Y390 HydrophobicContact CG2-CD1 3.26Å; V36-Y390 HydrophobicContact CG2-CD2 4.45Å; V36-Y390 HydrophobicContact CG2-CE1 3.51Å; V36-Y390 HydrophobicContact CG2-CG 3.78Å; V36-P398 HydrophobicContact CG1-CB 4.33Å; V36-P398 HydrophobicContact CG1-CG 4.18Å; V36-P398 HydrophobicContact CG2-CB 4.39Å; V36-V742 HydrophobicContact CG1-CG2 4.1Å; V36-V742 HydrophobicContact CG2-CG2 3.9Å
37Q98.3Very high96.7Very high160 Ų16035.6 Ų35.675%0.74819%0.191SC*.Hα-helixtrans-65.2-42.2178-70.1-178.8-12.200111.9T35 K40 A41T35-Q37 PolarHBondContact O-N 2.92Å; Q37-K40 PolarHBondContact O-N 3.06Å; Q37-A41 WeakPolarHBondContact O-CB 3.45Å; Q37-A41 PolarHBondContact O-N 3.27Å
38E98.6Very high97.4Very high14 Ų1438.1 Ų38.17%0.06522%0.217CC..Hα-helixtrans-63.3-45.9176.3-72.5172.9138.100111.5L34 T35 K40 A41 I42 R93 L117 P118L34-E38 WeakPolarHBondContact CA-OE2 3.34Å; L34-E38 HydrophobicContact CB-CB 4.49Å; L34-E38 HydrophobicContact CD2-CB 4.46Å; T35-E38 PolarHBondContact N-OE2 3.44Å; T35-E38 PolarHBondContact O-N 2.91Å; T35-E38 VanDerWaalsContact O-N 3.08Å; T35-E38 VanDerWaalsContact OG1-CG 3.25Å; T35-E38 WeakPolarHBondContact OG1-CG 3.39Å; T35-E38 PolarHBondContact OG1-N 3.36Å; T35-E38 PolarHBondContact OG1-OE2 3.08Å; E38-K40 PolarHBondContact O-N 2.94Å; E38-A41 PolarHBondContact O-N 2.96Å; E38-I42 VanDerWaalsContact O-CD1 3.32Å; E38-I42 WeakPolarHBondContact O-CD1 3.32Å; E38-I42 WeakPolarHBondContact O-CG1 3.27Å; E38-I42 PolarHBondContact O-N 3.31Å; E38-R93 VanDerWaalsContact OE1-CD 3.29Å; E38-R93 WeakPolarHBondContact OE1-CD 3.26Å; E38-R93 IonicContact OE1-CZ 3.91Å; E38-R93 IonicContact OE1-NE 2.81Å; E38-R93 PolarHBondContact OE1-NE 2.89Å; E38-R93 IonicContact OE1-NH2 3.9Å; E38-R93 IonicContact OE2-CZ 3.44Å; E38-R93 IonicContact OE2-NE 2.83Å; E38-R93 PolarHBondContact OE2-NE 3.11Å; E38-R93 IonicContact OE2-NH2 3.97Å; E38-R93 PolarHBondContact OE2-NH2 2.85Å; E38-L117 HydrophobicContact CB-CD1 4.33Å; E38-L117 HydrophobicContact CB-CD2 4.45Å; E38-L117 HydrophobicContact CG-CB 4.33Å; E38-L117 HydrophobicContact CG-CD1 4.37Å; E38-P118 HydrophobicContact CG-CB 4.24Å
39M98.7Very high97.8Very high2 Ų239 Ų391%0.0122%0.221CC..Hα-helixtrans-60.7-43.8176.8-70.8-177.7-94.600112.1L34 T35 V36 A41 I42 R43 M70 P398L34-M39 HydrophobicContact CB-CE 4.4Å; L34-M39 HydrophobicContact CB-CG 3.82Å; L34-M39 HydrophobicContact CB-SD 4.49Å; L34-M39 HydrophobicContact CD1-CG 4.1Å; L34-M39 VanDerWaalsContact O-CE 3.29Å; L34-M39 WeakPolarHBondContact O-CE 2.96Å; T35-M39 PolarHBondContact O-N 3.43Å; V36-M39 PolarHBondContact O-N 3.01Å; M39-A41 VanDerWaalsContact C-N 3.35Å; M39-A41 PolarHBondContact O-N 3.26Å; M39-I42 PolarHBondContact O-N 3.37Å; M39-R43 PolarHBondContact O-N 2.95Å; M39-M70 HydrophobicContact CB-SD 4.32Å; M39-P398 HydrophobicContact CB-CB 4.47Å; M39-P398 HydrophobicContact CB-CG 3.62Å; M39-P398 HydrophobicContact CE-CB 3.96Å; M39-P398 HydrophobicContact CE-CG 4.41Å; M39-P398 HydrophobicContact CG-CG 4.47Å; M39-P398 HydrophobicContact SD-CB 3.96Å; M39-P398 HydrophobicContact SD-CG 4.12Å
40K98.5Very high98Very high86 Ų8642.3 Ų42.337%0.37424%0.242SC..Hα-helixtrans-63-39.6175.3-73.8179.1179.2179.80112.2V36 Q37 E38 S44 P398 V742V36-K40 HydrophobicContact CG1-CD 4.1Å; V36-K40 WeakPolarHBondContact O-CB 3.19Å; V36-K40 WeakPolarHBondContact O-CG 3.36Å; V36-K40 PolarHBondContact O-N 3.15Å; Q37-K40 PolarHBondContact O-N 3.06Å; E38-K40 PolarHBondContact O-N 2.94Å; K40-S44 WeakPolarHBondContact O-CB 3.5Å; K40-S44 PolarHBondContact O-N 3.36Å; K40-S44 PolarHBondContact O-OG 3.31Å; K40-P398 HydrophobicContact CG-CG 4.29Å; K40-V742 WeakPolarHBondContact CE-O 3.43Å; K40-V742 VanDerWaalsContact NZ-C 3.26Å; K40-V742 PolarHBondContact NZ-O 2.87Å; K40-V742 PolarHBondContact NZ-OXT 2.94Å
41A98.6Very high98Very high28 Ų2848.9 Ų48.923%0.23127%0.273CS..Hα-helixtrans-66.9-42.6177.200000112Q37 E38 M39 S44 Y45 P118 P120Q37-A41 WeakPolarHBondContact O-CB 3.45Å; Q37-A41 PolarHBondContact O-N 3.27Å; E38-A41 PolarHBondContact O-N 2.96Å; M39-A41 VanDerWaalsContact C-N 3.35Å; M39-A41 PolarHBondContact O-N 3.26Å; A41-S44 PolarHBondContact O-N 3.16Å; A41-Y45 WeakPolarHBondContact O-CB 3.33Å; A41-Y45 PolarHBondContact O-N 2.91Å; A41-P118 WeakPolarHBondContact CB-O 3.22Å; A41-P120 HydrophobicContact CB-CG 4.36Å
42I98.6Very high97.9Very high0 Ų049.3 Ų49.30%028%0.275CS..Hα-helixtrans-60.6-50175-67.5156.8000110.4L34 E38 M39 S44 Y45 L46 M70 A95 V97 V114 L117L34-I42 HydrophobicContact CD1-CD1 3.88Å; E38-I42 VanDerWaalsContact O-CD1 3.32Å; E38-I42 WeakPolarHBondContact O-CD1 3.32Å; E38-I42 WeakPolarHBondContact O-CG1 3.27Å; E38-I42 PolarHBondContact O-N 3.31Å; M39-I42 PolarHBondContact O-N 3.37Å; I42-S44 VanDerWaalsContact C-N 3.35Å; I42-S44 PolarHBondContact O-N 3.37Å; I42-Y45 PolarHBondContact O-N 3.19Å; I42-L46 HydrophobicContact CG2-CD1 3.82Å; I42-L46 HydrophobicContact CG2-CG 4.44Å; I42-L46 WeakPolarHBondContact O-CG 3.17Å; I42-L46 PolarHBondContact O-N 2.96Å; I42-M70 HydrophobicContact CB-CE 4.37Å; I42-M70 HydrophobicContact CB-SD 3.98Å; I42-M70 HydrophobicContact CG2-CE 3.82Å; I42-M70 HydrophobicContact CG2-SD 3.7Å; I42-A95 HydrophobicContact CD1-CB 3.36Å; I42-A95 HydrophobicContact CG1-CB 4.28Å; I42-V97 HydrophobicContact CG2-CG2 3.63Å; I42-V114 HydrophobicContact CG1-CG1 4.47Å; I42-V114 HydrophobicContact CG2-CG1 4.28Å; I42-L117 HydrophobicContact CD1-CD1 4.22Å; I42-L117 HydrophobicContact CD1-CD2 3.78Å; I42-L117 HydrophobicContact CG1-CD2 3.58Å
43R97.9Very high97.8Very high52 Ų5255 Ų5520%0.19630%0.296CS..Hα-helixtrans-56.1-51.2177.3-171.2-175.3-172.9-743.5110.7M39 Y45 L46 H47 D56 I67 M70 Y392 D396M39-R43 PolarHBondContact O-N 2.95Å; R43-Y45 VanDerWaalsContact C-N 3.31Å; R43-Y45 PolarHBondContact O-N 2.94Å; R43-L46 PolarHBondContact O-N 3.44Å; R43-H47 VanDerWaalsContact CG-CD2 3.48Å; R43-H47 WeakPolarHBondContact CG-CD2 3.3Å; R43-H47 VanDerWaalsContact CZ-NE2 3.29Å; R43-H47 PolarHBondContact NH1-NE2 2.94Å; R43-H47 WeakPolarHBondContact O-CB 3.17Å; R43-H47 PolarHBondContact O-CD2 3.08Å; R43-H47 VanDerWaalsContact O-CD2 3.24Å; R43-H47 PolarHBondContact O-N 3.24Å; R43-D56 IonicContact NH2-OD1 3.84Å; R43-D56 PolarHBondContact NH2-OD1 2.81Å; R43-I67 HydrophobicContact CG-CD1 4.34Å; R43-M70 HydrophobicContact CB-CE 3.83Å; R43-M70 HydrophobicContact CG-CE 4.44Å; R43-Y392 PolarHBondContact NE-OH 3.03Å; R43-D396 VanDerWaalsContact CD-O 3.24Å; R43-D396 WeakPolarHBondContact CD-O 3.29Å; R43-D396 PolarHBondContact NE-O 3.04Å; R43-D396 IonicContact NH2-OD1 2.91Å; R43-D396 PolarHBondContact NH2-OD1 3.14Å
44S98Very high97.7Very high82 Ų8254.4 Ų54.457%0.57329%0.292SS*.Hα-helixtrans-59.5-42.6-178.3-570000112K40 A41 I42 G48K40-S44 WeakPolarHBondContact O-CB 3.5Å; K40-S44 PolarHBondContact O-N 3.36Å; K40-S44 PolarHBondContact O-OG 3.31Å; A41-S44 PolarHBondContact O-N 3.16Å; I42-S44 VanDerWaalsContact C-N 3.35Å; I42-S44 PolarHBondContact O-N 3.37Å; S44-G48 PolarHBondContact O-N 3.15Å; S44-G48 VanDerWaalsContact O-N 3.08Å
45Y98.5Very high97.6Very high50 Ų5056.4 Ų56.420%0.19631%0.305CS..Hα-helixtrans-63-48.2176.3166-101.4000112.3A41 I42 R43 G48 I49 V114 P120 R121 S122 H123A41-Y45 WeakPolarHBondContact O-CB 3.33Å; A41-Y45 PolarHBondContact O-N 2.91Å; I42-Y45 PolarHBondContact O-N 3.19Å; R43-Y45 VanDerWaalsContact C-N 3.31Å; R43-Y45 PolarHBondContact O-N 2.94Å; Y45-G48 PolarHBondContact O-N 3.42Å; Y45-G48 VanDerWaalsContact O-N 3.16Å; Y45-I49 HydrophobicContact CE1-CD1 4.01Å; Y45-V114 HydrophobicContact CD1-CG1 3.78Å; Y45-V114 HydrophobicContact CE1-CG1 3.85Å; Y45-P120 HydrophobicContact CD1-CB 4.08Å; Y45-P120 HydrophobicContact CD1-CG 4.39Å; Y45-P120 WeakPolarHBondContact CD2-O 3.42Å; Y45-P120 HydrophobicContact CG-CB 4.06Å; Y45-P120 HydrophobicContact CG-CG 4.04Å; Y45-R121 PolarHBondContact OH-O 3.47Å; Y45-S122 WeakPolarHBondContact OH-CA 3.31Å; Y45-S122 PolarHBondContact OH-N 3.22Å; Y45-H123 HydrophobicContact CE1-CB 4.16Å; Y45-H123 AromaticContact CE1-ND1 3.86Å; Y45-H123 AromaticContact CZ-ND1 3.74Å; Y45-H123 PolarHBondContact OH-N 3.47Å; Y45-H123 PolarHBondContact OH-ND1 2.92Å
46L98.4Very high97.3Very high0 Ų057.4 Ų57.40%031%0.308CS..Hα-helixtrans-68.1-41-178.3-67.7172.6000112.6I42 R43 G48 I49 M52 L54 I67 V97 I99 V114I42-L46 HydrophobicContact CG2-CD1 3.82Å; I42-L46 HydrophobicContact CG2-CG 4.44Å; I42-L46 WeakPolarHBondContact O-CG 3.17Å; I42-L46 PolarHBondContact O-N 2.96Å; R43-L46 PolarHBondContact O-N 3.44Å; L46-G48 PolarHBondContact O-N 3.44Å; L46-I49 HydrophobicContact CD2-CD1 4.2Å; L46-I49 WeakPolarHBondContact O-CB 3.14Å; L46-I49 PolarHBondContact O-N 2.82Å; L46-I49 VanDerWaalsContact O-N 3.15Å; L46-M52 HydrophobicContact CB-SD 4.33Å; L46-M52 HydrophobicContact CD2-CE 3.83Å; L46-M52 HydrophobicContact CD2-SD 3.82Å; L46-L54 HydrophobicContact CB-CD1 3.74Å; L46-I67 HydrophobicContact CB-CD1 4.23Å; L46-I67 HydrophobicContact CD1-CD1 3.87Å; L46-V97 HydrophobicContact CD1-CB 4.27Å; L46-V97 HydrophobicContact CD1-CG1 3.67Å; L46-V97 HydrophobicContact CD1-CG2 4.24Å; L46-I99 HydrophobicContact CD1-CD1 4.34Å; L46-V114 HydrophobicContact CD1-CG2 4.33Å; L46-V114 HydrophobicContact CD2-CG2 4.1Å
47H97.6Very high96.9Very high57 Ų5756 Ų5626%0.26430%0.299SS..Hα-helixtrans-65.6-23.1173.2-82.4-96.3000112.6R43 I49R43-H47 VanDerWaalsContact CG-CD2 3.48Å; R43-H47 WeakPolarHBondContact CG-CD2 3.3Å; R43-H47 VanDerWaalsContact CZ-NE2 3.29Å; R43-H47 PolarHBondContact NH1-NE2 2.94Å; R43-H47 WeakPolarHBondContact O-CB 3.17Å; R43-H47 PolarHBondContact O-CD2 3.08Å; R43-H47 VanDerWaalsContact O-CD2 3.24Å; R43-H47 PolarHBondContact O-N 3.24Å; H47-I49 PolarHBondContact O-N 3.28Å
48G97.5Very high96.5Very high56 Ų5656.2 Ų56.258%0.57729%0.294SS*.THydrogen-bonded Turntrans-74-4.9174.300000114.6S44 Y45 L46 P50S44-G48 PolarHBondContact O-N 3.15Å; S44-G48 VanDerWaalsContact O-N 3.08Å; Y45-G48 PolarHBondContact O-N 3.42Å; Y45-G48 VanDerWaalsContact O-N 3.16Å; L46-G48 PolarHBondContact O-N 3.44Å; G48-P50 WeakPolarHBondContact O-CD 3.37Å
49I98Very high96.1Very high25 Ų2557.5 Ų57.513%0.12830%0.304CS..  trans-97.4102.9179.9-59.7166.5000108.8Y45 L46 H47 E51 M52 H123Y45-I49 HydrophobicContact CE1-CD1 4.01Å; L46-I49 HydrophobicContact CD2-CD1 4.2Å; L46-I49 WeakPolarHBondContact O-CB 3.14Å; L46-I49 PolarHBondContact O-N 2.82Å; L46-I49 VanDerWaalsContact O-N 3.15Å; H47-I49 PolarHBondContact O-N 3.28Å; I49-E51 HydrophobicContact CG2-CB 4.39Å; I49-E51 WeakPolarHBondContact CG2-OE2 3.49Å; I49-E51 PolarHBondContact O-N 2.99Å; I49-E51 VanDerWaalsContact O-N 3.15Å; I49-M52 HydrophobicContact CB-CG 4.12Å; I49-M52 HydrophobicContact CB-SD 4.19Å; I49-M52 HydrophobicContact CD1-CE 3.65Å; I49-M52 HydrophobicContact CD1-SD 3.95Å; I49-M52 HydrophobicContact CG2-CE 4.4Å; I49-M52 HydrophobicContact CG2-CG 3.85Å; I49-M52 HydrophobicContact CG2-SD 4.36Å; I49-M52 PolarHBondContact O-N 3.48Å; I49-M52 VanDerWaalsContact O-N 3.14Å; I49-H123 VanDerWaalsContact CD1-CE1 3.47Å; I49-H123 WeakPolarHBondContact CD1-CE1 3.37Å; I49-H123 WeakPolarHBondContact CD1-ND1 3.33Å
50P96Very high95.5Very high100 Ų10065.3 Ų65.365%0.64934%0.34SS*.G310 helixtrans-60.1-30.4-173-24.435.9000113.6G48 M52 K53G48-P50 WeakPolarHBondContact O-CD 3.37Å; P50-M52 VanDerWaalsContact C-N 3.27Å; P50-M52 PolarHBondContact O-N 3.43Å; P50-K53 WeakPolarHBondContact O-CG 3.37Å; P50-K53 PolarHBondContact O-N 3.25Å
51E95.3Very high95.3Very high150 Ų15064.4 Ų64.470%0.70134%0.342SS*.G310 helixtrans-66-28.3-178.5-6078.3-171.500112.6I49 K53I49-E51 HydrophobicContact CG2-CB 4.39Å; I49-E51 WeakPolarHBondContact CG2-OE2 3.49Å; I49-E51 PolarHBondContact O-N 2.99Å; I49-E51 VanDerWaalsContact O-N 3.15Å; E51-K53 VanDerWaalsContact C-N 3.33Å
52M95.2Very high95.1Very high9 Ų963.5 Ų63.54%0.04433%0.333CS..G310 helixtrans-75.4-24.1179.5-65.2-174.1175.200112.6L46 I49 P50 L54 N65 I99 F101 Y112 H123L46-M52 HydrophobicContact CB-SD 4.33Å; L46-M52 HydrophobicContact CD2-CE 3.83Å; L46-M52 HydrophobicContact CD2-SD 3.82Å; I49-M52 HydrophobicContact CB-CG 4.12Å; I49-M52 HydrophobicContact CB-SD 4.19Å; I49-M52 HydrophobicContact CD1-CE 3.65Å; I49-M52 HydrophobicContact CD1-SD 3.95Å; I49-M52 HydrophobicContact CG2-CE 4.4Å; I49-M52 HydrophobicContact CG2-CG 3.85Å; I49-M52 HydrophobicContact CG2-SD 4.36Å; I49-M52 PolarHBondContact O-N 3.48Å; I49-M52 VanDerWaalsContact O-N 3.14Å; P50-M52 VanDerWaalsContact C-N 3.27Å; P50-M52 PolarHBondContact O-N 3.43Å; M52-L54 HydrophobicContact CB-CD1 4.35Å; M52-L54 HydrophobicContact CB-CD2 4.28Å; M52-L54 HydrophobicContact CB-CG 3.82Å; M52-L54 PolarHBondContact O-N 3.47Å; M52-L54 HydrophobicContact SD-CD1 4.3Å; M52-N65 WeakPolarHBondContact O-CB 3.48Å; M52-N65 PolarHBondContact O-ND2 3.5Å; M52-I99 HydrophobicContact SD-CD1 4Å; M52-F101 HydrophobicContact CB-CE1 4.38Å; M52-Y112 HydrophobicContact CE-CE1 4.42Å; M52-H123 WeakPolarHBondContact CE-NE2 3.26Å
53K96.2Very high94.9Very high141 Ų14167.5 Ų67.561%0.61335%0.351SS*.  trans48.740.9-179-57.4-179.9-178.7177.70113.2P50 E51 T55P50-K53 WeakPolarHBondContact O-CG 3.37Å; P50-K53 PolarHBondContact O-N 3.25Å; E51-K53 VanDerWaalsContact C-N 3.33Å; K53-T55 PolarHBondContact O-N 2.91Å
54L96.9Very high94.8Very high23 Ų2365.4 Ų65.412%0.1234%0.343CS..BIsolated β-bridgetrans-66.5132.3-177.1-63.9177.7000111.3L46 M52 N65 I67 I99L46-L54 HydrophobicContact CB-CD1 3.74Å; M52-L54 HydrophobicContact CB-CD1 4.35Å; M52-L54 HydrophobicContact CB-CD2 4.28Å; M52-L54 HydrophobicContact CB-CG 3.82Å; M52-L54 PolarHBondContact O-N 3.47Å; M52-L54 HydrophobicContact SD-CD1 4.3Å; L54-N65 CarbonylContact C-O 3.56Å; L54-N65 WeakPolarHBondContact CA-O 3.35Å; L54-N65 HydrophobicContact CD2-CB 4.21Å; L54-I67 HydrophobicContact CD1-CD1 4.02Å; L54-I67 HydrophobicContact CD1-CG1 3.9Å; L54-I67 HydrophobicContact CD2-CG1 4.47Å; L54-I99 HydrophobicContact CD1-CD1 4.49Å; L54-I99 HydrophobicContact CD2-CD1 4.37Å; L54-I99 HydrophobicContact CD2-CG2 3.63Å
55T95.6Very high94.7Very high52 Ų5261.7 Ų61.732%0.31932%0.317SS..  trans-111.4176.3171.1660000109.7K53 R64 N65K53-T55 PolarHBondContact O-N 2.91Å; T55-R64 WeakPolarHBondContact OG1-CB 3.37Å; T55-N65 PolarHBondContact N-O 3.19Å; T55-N65 PolarHBondContact OG1-O 2.76Å
56D93.1Very high94.7Very high88 Ų8859.4 Ų59.447%0.47131%0.308SS..  trans-65.6142.1174.4-67.3-24.8000111.2R43 R58 S59 D396R43-D56 IonicContact NH2-OD1 3.84Å; R43-D56 PolarHBondContact NH2-OD1 2.81Å; D56-R58 PolarHBondContact O-N 3.44Å; D56-S59 WeakPolarHBondContact O-CB 3.48Å; D56-S59 PolarHBondContact O-N 2.95Å; D56-D396 WeakPolarHBondContact CA-OD1 3.35Å; D56-D396 WeakPolarHBondContact CB-OD2 3.34Å
57A90.4Very high94.7Very high1 Ų159.5 Ų59.51%0.00831%0.308CS..THydrogen-bonded Turntrans-60.9-27.9-179.600000111.9R64 D396A57-R64 PolarHBondContact O-NE 3.21Å; A57-R64 VanDerWaalsContact O-NE 3.12Å; A57-R64 PolarHBondContact O-NH2 3.25Å; A57-D396 VanDerWaalsContact N-CG 3.28Å; A57-D396 PolarHBondContact N-OD1 2.85Å; A57-D396 PolarHBondContact N-OD2 3.07Å; A57-D396 VanDerWaalsContact N-OD2 3.07Å
58R89.3Confident94.7Very high165 Ų16556.9 Ų56.962%0.62330%0.296SS*.THydrogen-bonded Turntrans-96.614.4179.3-61.8-169.2176.5-161.8-3.2115.3D56 E60 I143 D396D56-R58 PolarHBondContact O-N 3.44Å; R58-E60 PolarHBondContact O-N 2.9Å; R58-I143 HydrophobicContact CG-CG2 4.32Å; R58-D396 PolarHBondContact N-OD2 3.17Å
59S89.3Confident94.7Very high40 Ų4054.2 Ų54.228%0.2827%0.269SS..  trans-60.2133.6172.2160.60000111D56 T61 R64 V144D56-S59 WeakPolarHBondContact O-CB 3.48Å; D56-S59 PolarHBondContact O-N 2.95Å; S59-T61 VanDerWaalsContact C-N 3.27Å; S59-T61 PolarHBondContact O-N 2.79Å; S59-T61 VanDerWaalsContact O-N 3.13Å; S59-R64 PolarHBondContact O-NH1 2.76Å; S59-V144 WeakPolarHBondContact O-CG1 3.48Å
60E87.6Confident94.8Very high167 Ų16753 Ų5378%0.7826%0.263SS*.SBendtrans-55.9-33.4-174.1-67.6-179.6179.100114.1R58 V144 H148R58-E60 PolarHBondContact O-N 2.9Å; E60-V144 VanDerWaalsContact O-CG1 3.27Å; E60-V144 WeakPolarHBondContact O-CG1 3.39Å; E60-H148 PolarHBondContact O-NE2 3.16Å
61T93.2Very high94.9Very high66 Ų6648.5 Ų48.541%0.40523%0.233SC..  trans-79.8139.6178.7-173.40000113S59 K63 R64S59-T61 VanDerWaalsContact C-N 3.27Å; S59-T61 PolarHBondContact O-N 2.79Å; S59-T61 VanDerWaalsContact O-N 3.13Å; T61-K63 VanDerWaalsContact C-N 3.32Å; T61-K63 PolarHBondContact OG1-N 3.35Å; T61-K63 VanDerWaalsContact OG1-N 3.16Å; T61-R64 HydrophobicContact CG2-CB 4.38Å; T61-R64 VanDerWaalsContact O-CD 3.3Å; T61-R64 WeakPolarHBondContact O-CD 3.45Å; T61-R64 WeakPolarHBondContact O-CG 3.18Å; T61-R64 PolarHBondContact O-NH1 2.94Å
62L94.4Very high95.1Very high10 Ų1041.6 Ų41.65%0.05220%0.201CC..SBendtrans-77.4-17.3169.3-57.1174.9000112.8R64 V144 E145 L225 P227 W230L62-R64 PolarHBondContact O-N 3.33Å; L62-V144 HydrophobicContact CD2-CB 4.37Å; L62-V144 HydrophobicContact CD2-CG1 4.03Å; L62-E145 HydrophobicContact CD1-CG 4.33Å; L62-E145 HydrophobicContact CD2-CB 3.94Å; L62-E145 HydrophobicContact CD2-CG 4.44Å; L62-L225 HydrophobicContact CB-CD2 3.8Å; L62-P227 HydrophobicContact CD1-CG 4.07Å; L62-P227 HydrophobicContact CG-CG 4.49Å; L62-W230 HydrophobicContact CD1-CH2 4Å; L62-W230 HydrophobicContact CD1-CZ2 3.43Å; L62-W230 VanDerWaalsContact CD1-CZ2 3.43Å
63K95Very high95.2Very high83 Ų8343.7 Ų43.736%0.36121%0.21SC..SBendtrans-78.362.8172.6-66.4179.4-176.5164.20110.6T61 N103 L225 D226T61-K63 VanDerWaalsContact C-N 3.32Å; T61-K63 PolarHBondContact OG1-N 3.35Å; T61-K63 VanDerWaalsContact OG1-N 3.16Å; K63-N103 WeakPolarHBondContact O-CB 3.29Å; K63-L225 HydrophobicContact CD-CB 4.48Å; K63-L225 HydrophobicContact CG-CB 3.61Å; K63-L225 HydrophobicContact CG-CD1 4.24Å; K63-D226 IonicContact NZ-OD2 2.71Å
64R94.9Very high95.3Very high8 Ų838.9 Ų38.93%0.0319%0.191CC..  trans-133157-176.368.9177.2-178-91.8-0.4112.4T55 A57 S59 T61 L62 G102 V144T55-R64 WeakPolarHBondContact OG1-CB 3.37Å; A57-R64 PolarHBondContact O-NE 3.21Å; A57-R64 VanDerWaalsContact O-NE 3.12Å; A57-R64 PolarHBondContact O-NH2 3.25Å; S59-R64 PolarHBondContact O-NH1 2.76Å; T61-R64 HydrophobicContact CG2-CB 4.38Å; T61-R64 VanDerWaalsContact O-CD 3.3Å; T61-R64 WeakPolarHBondContact O-CD 3.45Å; T61-R64 WeakPolarHBondContact O-CG 3.18Å; T61-R64 PolarHBondContact O-NH1 2.94Å; L62-R64 PolarHBondContact O-N 3.33Å; R64-G102 VanDerWaalsContact O-CA 3.27Å; R64-G102 WeakPolarHBondContact O-CA 3.41Å; R64-G102 PolarHBondContact O-N 2.94Å; R64-V144 VanDerWaalsContact NH1-CG1 3.33Å
65N97.3Very high95.2Very high5 Ų538.7 Ų38.73%0.02719%0.191CC..EExtended strand (participates in β ladder)trans-102.5120.5168.6-60.7-10.9000107.8M52 L54 T55 Q100 F101 G102 N103M52-N65 WeakPolarHBondContact O-CB 3.48Å; M52-N65 PolarHBondContact O-ND2 3.5Å; L54-N65 CarbonylContact C-O 3.56Å; L54-N65 WeakPolarHBondContact CA-O 3.35Å; L54-N65 HydrophobicContact CD2-CB 4.21Å; T55-N65 PolarHBondContact N-O 3.19Å; T55-N65 PolarHBondContact OG1-O 2.76Å; N65-Q100 CarbonylContact C-O 3.57Å; N65-Q100 WeakPolarHBondContact CA-O 3.39Å; N65-F101 HydrophobicContact CB-CD1 4.03Å; N65-F101 VanDerWaalsContact OD1-CA 3.3Å; N65-F101 WeakPolarHBondContact OD1-CA 3.26Å; N65-G102 PolarHBondContact OD1-N 3.18Å; N65-N103 WeakPolarHBondContact OD1-CB 3.35Å; N65-N103 PolarHBondContact OD1-N 3.26Å
66S97.4Very high95.3Very high1 Ų141.5 Ų41.51%0.00720%0.199CC..EExtended strand (participates in β ladder)trans-146.7153.5-175.765.20000112.4L68 I99 Q100S66-L68 PolarHBondContact O-N 3.12Å; S66-I99 WeakPolarHBondContact O-CA 3.47Å; S66-I99 WeakPolarHBondContact O-CG2 3.38Å; S66-Q100 PolarHBondContact N-O 3.17Å; S66-Q100 PolarHBondContact O-N 3Å
67I98.1Very high95.5Very high3 Ų337.5 Ų37.52%0.01518%0.177CC..EExtended strand (participates in β ladder)trans-79.3116.6174.9-54.4179.2000108.1R43 L46 L54 M70 V97 I99 Y392R43-I67 HydrophobicContact CG-CD1 4.34Å; L46-I67 HydrophobicContact CB-CD1 4.23Å; L46-I67 HydrophobicContact CD1-CD1 3.87Å; L54-I67 HydrophobicContact CD1-CD1 4.02Å; L54-I67 HydrophobicContact CD1-CG1 3.9Å; L54-I67 HydrophobicContact CD2-CG1 4.47Å; I67-M70 HydrophobicContact CB-CE 4.41Å; I67-M70 HydrophobicContact CD1-CE 3.43Å; I67-M70 VanDerWaalsContact CD1-CE 3.43Å; I67-M70 HydrophobicContact CG1-CE 4.46Å; I67-M70 HydrophobicContact CG2-CE 3.7Å; I67-M70 HydrophobicContact CG2-CG 3.99Å; I67-V97 HydrophobicContact CG2-CG1 3.63Å; I67-I99 HydrophobicContact CG1-CG1 4.47Å; I67-Y392 HydrophobicContact CB-CE1 4.16Å; I67-Y392 HydrophobicContact CG2-CD1 4.36Å; I67-Y392 HydrophobicContact CG2-CE1 3.84Å
68L97.9Very high95.8Very high1 Ų140.6 Ų40.61%0.00519%0.191CC..EExtended strand (participates in β ladder)trans-84.4-45.2179.2178.166.3000112.3S66 I98 Q100 I109 P140 T142 F393 D394 I627S66-L68 PolarHBondContact O-N 3.12Å; L68-I98 HydrophobicContact CB-CB 4.43Å; L68-I98 HydrophobicContact CB-CG2 4.39Å; L68-I98 HydrophobicContact CD2-CG2 4.16Å; L68-I98 PolarHBondContact N-O 3.44Å; L68-Q100 HydrophobicContact CB-CG 4.15Å; L68-Q100 HydrophobicContact CD2-CG 4.33Å; L68-I109 HydrophobicContact CD2-CD1 4.07Å; L68-P140 HydrophobicContact CD2-CG 4.03Å; L68-T142 HydrophobicContact CD1-CG2 4.17Å; L68-F393 HydrophobicContact CD1-CD2 4.43Å; L68-F393 HydrophobicContact CD1-CE2 3.97Å; L68-F393 HydrophobicContact CG-CD2 4.43Å; L68-F393 HydrophobicContact CG-CE2 4.1Å; L68-F393 CarbonylContact O-C 3.58Å; L68-F393 VanDerWaalsContact O-CA 3.26Å; L68-F393 WeakPolarHBondContact O-CA 3.43Å; L68-D394 HydrophobicContact CD1-CB 4.4Å; L68-D394 PolarHBondContact O-N 2.94Å; L68-I627 HydrophobicContact CD2-CD1 4.21Å
69L98.6Very high96.1Very high0 Ų035.3 Ų35.30%017%0.174CC..EExtended strand (participates in β ladder)trans-143.8140-172.8-179.175.8000110.5E71 V97 I98 Y392 F393 I627L69-E71 HydrophobicContact CD2-CG 4.26Å; L69-V97 CarbonylContact O-C 3.54Å; L69-V97 VanDerWaalsContact O-CA 3.32Å; L69-V97 WeakPolarHBondContact O-CA 3.49Å; L69-I98 HydrophobicContact CB-CB 4.11Å; L69-I98 HydrophobicContact CB-CD1 3.99Å; L69-I98 HydrophobicContact CB-CG1 4.07Å; L69-I98 HydrophobicContact CD2-CD1 3.59Å; L69-I98 HydrophobicContact CD2-CG1 4.23Å; L69-I98 HydrophobicContact CG-CD1 4.41Å; L69-I98 PolarHBondContact N-O 3.1Å; L69-I98 PolarHBondContact O-N 3.47Å; L69-Y392 CarbonylContact C-O 3.56Å; L69-Y392 VanDerWaalsContact CA-O 3.3Å; L69-Y392 WeakPolarHBondContact CA-O 3.47Å; L69-F393 HydrophobicContact CB-CD2 4.32Å; L69-F393 HydrophobicContact CD1-CB 4.06Å; L69-F393 HydrophobicContact CD1-CD2 3.85Å; L69-F393 HydrophobicContact CD1-CG 4.38Å; L69-I627 HydrophobicContact CD2-CD1 4.47Å
70M98.4Very high96.4Very high1 Ų133.4 Ų33.41%0.00516%0.161CC..EExtended strand (participates in β ladder)trans-124.5131.6160.2-52-177.9-179.700110.6L34 M39 I42 R43 I67 V97 Y392L34-M70 HydrophobicContact CD1-CB 4.2Å; M39-M70 HydrophobicContact CB-SD 4.32Å; I42-M70 HydrophobicContact CB-CE 4.37Å; I42-M70 HydrophobicContact CB-SD 3.98Å; I42-M70 HydrophobicContact CG2-CE 3.82Å; I42-M70 HydrophobicContact CG2-SD 3.7Å; R43-M70 HydrophobicContact CB-CE 3.83Å; R43-M70 HydrophobicContact CG-CE 4.44Å; I67-M70 HydrophobicContact CB-CE 4.41Å; I67-M70 HydrophobicContact CD1-CE 3.43Å; I67-M70 VanDerWaalsContact CD1-CE 3.43Å; I67-M70 HydrophobicContact CG1-CE 4.46Å; I67-M70 HydrophobicContact CG2-CE 3.7Å; I67-M70 HydrophobicContact CG2-CG 3.99Å; M70-V97 HydrophobicContact CG-CG1 4.19Å; M70-V97 HydrophobicContact CG-CG2 4.25Å; M70-Y392 HydrophobicContact CB-CD1 4.41Å; M70-Y392 HydrophobicContact CB-CG 4.25Å; M70-Y392 HydrophobicContact CE-CD1 4.37Å; M70-Y392 HydrophobicContact CE-CD2 4.45Å; M70-Y392 HydrophobicContact CE-CE1 4.06Å; M70-Y392 HydrophobicContact CE-CE2 4.12Å; M70-Y392 HydrophobicContact CG-CD1 3.81Å; M70-Y392 HydrophobicContact CG-CE1 4.35Å; M70-Y392 HydrophobicContact CG-CG 3.94Å; M70-Y392 PolarHBondContact N-O 3Å; M70-Y392 HydrophobicContact SD-CD1 4.28Å; M70-Y392 HydrophobicContact SD-CD2 4.06Å; M70-Y392 HydrophobicContact SD-CE2 4.31Å; M70-Y392 HydrophobicContact SD-CG 4.05Å
71E98.7Very high96.8Very high5 Ų526 Ų262%0.02313%0.126CC..EExtended strand (participates in β ladder)trans-148.6164.4172.163.9179-160.100111.5L34 L69 H73 A95 R96 R318 S320L34-E71 VanDerWaalsContact CD1-C 3.5Å; L69-E71 HydrophobicContact CD2-CG 4.26Å; E71-H73 PolarHBondContact O-N 3.25Å; E71-A95 CarbonylContact O-C 3.56Å; E71-A95 WeakPolarHBondContact O-CA 3.46Å; E71-R96 HydrophobicContact CG-CB 4.11Å; E71-R96 PolarHBondContact N-O 3.24Å; E71-R96 PolarHBondContact O-N 3.22Å; E71-R96 WeakPolarHBondContact OE1-CD 3.41Å; E71-R96 IonicContact OE1-CZ 3.53Å; E71-R96 IonicContact OE1-NE 2.99Å; E71-R96 IonicContact OE1-NH1 3.7Å; E71-R96 PolarHBondContact OE1-NH1 3.44Å; E71-R318 IonicContact OE1-CZ 2.97Å; E71-R318 IonicContact OE1-NE 3.1Å; E71-R318 PolarHBondContact OE1-NE 2.9Å; E71-R318 IonicContact OE1-NH2 2.71Å; E71-R318 PolarHBondContact OE1-NH2 2.91Å; E71-R318 VanDerWaalsContact OE2-CG 3.24Å; E71-R318 WeakPolarHBondContact OE2-CG 3.09Å; E71-R318 IonicContact OE2-NE 2.67Å; E71-S320 WeakPolarHBondContact OE2-CB 3.42Å; E71-S320 PolarHBondContact OE2-N 3.01Å; E71-S320 PolarHBondContact OE2-OG 3.11Å
72L98.6Very high96.8Very high5 Ų527.3 Ų27.33%0.02612%0.124CC..EExtended strand (participates in β ladder)trans-60.9128.6176.517674.9000110.7F31 A32 L34 L74 R93 R316F31-L72 WeakPolarHBondContact O-CD2 3.24Å; A32-L72 VanDerWaalsContact O-CD2 3.3Å; A32-L72 WeakPolarHBondContact O-CD2 3.02Å; L34-L72 HydrophobicContact CD2-CB 4.36Å; L34-L72 HydrophobicContact CD2-CD1 4.26Å; L34-L72 HydrophobicContact CG-CB 4.38Å; L72-L74 HydrophobicContact CD2-CD2 3.82Å; L72-R93 HydrophobicContact CD1-CG 4.12Å; L72-R93 VanDerWaalsContact CD1-NH1 3.28Å; L72-R316 PolarHBondContact O-NH1 2.7Å
73H98.3Very high96.7Very high53 Ų5327.6 Ų27.625%0.24513%0.128CC..EExtended strand (participates in β ladder)trans-85.1116.4163.2-175.259.4000108.8E71 Q94 R96 I113E71-H73 PolarHBondContact O-N 3.25Å; H73-Q94 HydrophobicContact CB-CB 4.09Å; H73-Q94 PolarHBondContact N-O 2.91Å; H73-R96 HydrophobicContact CB-CB 4.36Å; H73-I113 HydrophobicContact CB-CD1 4.11Å; H73-I113 HydrophobicContact CB-CG2 4.41Å; H73-I113 WeakPolarHBondContact ND1-CD1 3.41Å
74L97.4Very high96.5Very high40 Ų4024 Ų2421%0.20911%0.113CC..PPolyproline II helixtrans-68.7141.2-179.8-71.2168.1000110.5F31 L72 F326F31-L74 HydrophobicContact CD1-CD2 3.89Å; L72-L74 HydrophobicContact CD2-CD2 3.82Å; L74-F326 HydrophobicContact CD1-CE1 3.91Å; L74-F326 HydrophobicContact CD1-CZ 3.56Å; L74-F326 HydrophobicContact CD2-CE1 4.3Å; L74-F326 HydrophobicContact CD2-CZ 4.07Å; L74-F326 HydrophobicContact CG-CZ 4.5Å
75P96.2Very high96.3Very high19 Ų1927.4 Ų27.412%0.12313%0.131CC..PPolyproline II helixtrans-64.9157.2172.629.3-35.6000110.9K77 A80 P91P75-K77 PolarHBondContact O-N 3.16Å; P75-A80 HydrophobicContact CG-CB 4.1Å; P75-P91 HydrophobicContact CB-CB 3.87Å; P75-P91 HydrophobicContact CB-CG 3.35Å; P75-P91 HydrophobicContact CG-CG 3.92Å
76K97Very high95.7Very high110 Ų11035.4 Ų35.448%0.47816%0.161SC..PPolyproline II helixtrans-59.4138.2172.3-63.9179-174166.40109.9H78 E79 A80K76-H78 PolarHBondContact O-N 3.18Å; K76-H78 VanDerWaalsContact O-N 3.14Å; K76-E79 HydrophobicContact CB-CG 4.1Å; K76-E79 WeakPolarHBondContact O-CB 3.33Å; K76-E79 PolarHBondContact O-N 3.27Å; K76-A80 PolarHBondContact O-N 3.36Å; K76-A80 VanDerWaalsContact O-N 3.09Å
77K97.6Very high95.1Very high4 Ų438.9 Ų38.92%0.01720%0.197CC..Hα-helixtrans-53-43.6-173.7179174.7-179.4-177.90112P75 E79 A80 L81 Y337 D508 D510 D619 D654P75-K77 PolarHBondContact O-N 3.16Å; K77-E79 VanDerWaalsContact C-N 3.3Å; K77-E79 PolarHBondContact O-N 2.88Å; K77-A80 PolarHBondContact O-N 3.26Å; K77-L81 HydrophobicContact CG-CD1 3.89Å; K77-L81 HydrophobicContact CG-CG 4.26Å; K77-L81 WeakPolarHBondContact O-CB 3.44Å; K77-L81 VanDerWaalsContact O-CG 3.28Å; K77-L81 WeakPolarHBondContact O-CG 3.5Å; K77-L81 PolarHBondContact O-N 3.04Å; K77-Y337 HydrophobicContact CB-CE1 4.03Å; K77-Y337 HydrophobicContact CD-CD1 3.78Å; K77-Y337 HydrophobicContact CD-CD2 4.46Å; K77-Y337 HydrophobicContact CD-CE1 4.1Å; K77-Y337 HydrophobicContact CD-CG 3.98Å; K77-Y337 HydrophobicContact CG-CD1 3.92Å; K77-Y337 HydrophobicContact CG-CD2 4.06Å; K77-Y337 HydrophobicContact CG-CE1 3.79Å; K77-Y337 HydrophobicContact CG-CE2 3.93Å; K77-Y337 HydrophobicContact CG-CG 4.05Å; K77-D508 WeakPolarHBondContact CD-OD2 3.3Å; K77-D508 WeakPolarHBondContact CE-OD2 3.41Å; K77-D508 IonicContact NZ-OD1 3.14Å; K77-D508 PolarHBondContact NZ-OD1 3.39Å; K77-D508 IonicContact NZ-OD2 2.75Å; K77-D508 PolarHBondContact NZ-OD2 2.97Å; K77-D510 WeakPolarHBondContact CE-OD2 3.46Å; K77-D510 IonicContact NZ-OD1 3.33Å; K77-D510 PolarHBondContact NZ-OD1 3.37Å; K77-D510 IonicContact NZ-OD2 3.45Å; K77-D510 PolarHBondContact NZ-OD2 3.03Å; K77-D619 PolarHBondContact N-OD1 2.98Å; K77-D654 VanDerWaalsContact NZ-CG 3.32Å; K77-D654 IonicContact NZ-OD1 3.72Å; K77-D654 PolarHBondContact NZ-OD1 3.07Å; K77-D654 IonicContact NZ-OD2 3.19Å; K77-D654 PolarHBondContact NZ-OD2 3.27Å
78H96.1Very high94.6Very high66 Ų6643.3 Ų43.331%0.30622%0.217SC..Hα-helixtrans-64.8-30.4-179.573.6-91.7000113.7K76 R82 D619K76-H78 PolarHBondContact O-N 3.18Å; K76-H78 VanDerWaalsContact O-N 3.14Å; H78-R82 WeakPolarHBondContact O-CG 3.44Å; H78-R82 PolarHBondContact O-N 2.92Å; H78-D619 IonicContact ND1-OD2 3.72Å
79E95.9Very high94.2Very high55 Ų5547.6 Ų47.626%0.25725%0.253SS..Hα-helixtrans-76.3-43.8176.6-55.2-177.1160.200110.6K76 K77 L81 R82 A83 P91K76-E79 HydrophobicContact CB-CG 4.1Å; K76-E79 WeakPolarHBondContact O-CB 3.33Å; K76-E79 PolarHBondContact O-N 3.27Å; K77-E79 VanDerWaalsContact C-N 3.3Å; K77-E79 PolarHBondContact O-N 2.88Å; E79-L81 PolarHBondContact O-N 3.16Å; E79-R82 PolarHBondContact O-N 3.46Å; E79-A83 PolarHBondContact O-N 3.03Å; E79-P91 HydrophobicContact CB-CB 4.11Å; E79-P91 HydrophobicContact CB-CG 4.31Å
80A95.9Very high93.8Very high0 Ų052 Ų520%027%0.272CS..Hα-helixtrans-57.2-48.617400000111.2M30 F31 P75 K76 K77 R82 A83 L84 Y337M30-A80 HydrophobicContact CE-CB 4.4Å; F31-A80 HydrophobicContact CZ-CB 4.29Å; P75-A80 HydrophobicContact CG-CB 4.1Å; K76-A80 PolarHBondContact O-N 3.36Å; K76-A80 VanDerWaalsContact O-N 3.09Å; K77-A80 PolarHBondContact O-N 3.26Å; A80-R82 VanDerWaalsContact C-N 3.31Å; A80-R82 PolarHBondContact O-N 2.81Å; A80-A83 WeakPolarHBondContact O-CB 3.49Å; A80-A83 PolarHBondContact O-N 2.82Å; A80-A83 VanDerWaalsContact O-N 3.07Å; A80-L84 VanDerWaalsContact O-CG 3.29Å; A80-L84 WeakPolarHBondContact O-CG 3.09Å; A80-L84 PolarHBondContact O-N 3.39Å; A80-Y337 HydrophobicContact CB-CE2 4.15Å; A80-Y337 WeakPolarHBondContact CB-OH 3.2Å
81L94.9Very high93.6Very high12 Ų1252.9 Ų52.96%0.06328%0.278CS..Hα-helixtrans-63.3-33.5179.2-69.6176.8000113.1K77 E79 A83 L84 D85 R334 Y337 R514K77-L81 HydrophobicContact CG-CD1 3.89Å; K77-L81 HydrophobicContact CG-CG 4.26Å; K77-L81 WeakPolarHBondContact O-CB 3.44Å; K77-L81 VanDerWaalsContact O-CG 3.28Å; K77-L81 WeakPolarHBondContact O-CG 3.5Å; K77-L81 PolarHBondContact O-N 3.04Å; E79-L81 PolarHBondContact O-N 3.16Å; L81-A83 VanDerWaalsContact C-N 3.32Å; L81-A83 PolarHBondContact O-N 3.1Å; L81-L84 HydrophobicContact CD2-CD1 4.47Å; L81-L84 PolarHBondContact O-N 2.86Å; L81-D85 VanDerWaalsContact O-CB 3.31Å; L81-D85 WeakPolarHBondContact O-CB 3.48Å; L81-D85 PolarHBondContact O-N 2.76Å; L81-R334 VanDerWaalsContact CD2-CZ 3.49Å; L81-Y337 HydrophobicContact CD2-CD2 3.99Å; L81-Y337 HydrophobicContact CD2-CE2 4.3Å; L81-Y337 HydrophobicContact CG-CD2 4.41Å; L81-Y337 HydrophobicContact CG-CE2 4.41Å; L81-R514 HydrophobicContact CD1-CG 4.02Å
82R93.6Very high93.5Very high93 Ų9356.6 Ų56.635%0.35130%0.303SS..Hα-helixtrans-63.4-39.6172.7-77-171.7-52.7-143.80111.8H78 E79 A80 R86 Q88H78-R82 WeakPolarHBondContact O-CG 3.44Å; H78-R82 PolarHBondContact O-N 2.92Å; E79-R82 PolarHBondContact O-N 3.46Å; A80-R82 VanDerWaalsContact C-N 3.31Å; A80-R82 PolarHBondContact O-N 2.81Å; R82-R86 CarbonylContact O-C 3.29Å; R82-R86 WeakPolarHBondContact O-CA 3.31Å; R82-R86 VanDerWaalsContact O-CB 3.28Å; R82-R86 WeakPolarHBondContact O-CB 3.46Å; R82-R86 PolarHBondContact O-N 3.36Å; R82-R86 VanDerWaalsContact O-N 3.14Å; R82-Q88 HydrophobicContact CB-CB 4.34Å; R82-Q88 HydrophobicContact CB-CG 4.42Å; R82-Q88 VanDerWaalsContact CD-OE1 3.26Å; R82-Q88 PolarHBondContact O-N 3.34Å
83A92.3Very high93.4Very high16 Ų1658.7 Ų58.713%0.13231%0.31CS..Hα-helixtrans-68.9-47.5174.600000111.4M30 E79 A80 L81 G87 Q88M30-A83 HydrophobicContact CE-CB 4.02Å; M30-A83 HydrophobicContact SD-CB 3.95Å; E79-A83 PolarHBondContact O-N 3.03Å; A80-A83 WeakPolarHBondContact O-CB 3.49Å; A80-A83 PolarHBondContact O-N 2.82Å; A80-A83 VanDerWaalsContact O-N 3.07Å; L81-A83 VanDerWaalsContact C-N 3.32Å; L81-A83 PolarHBondContact O-N 3.1Å; A83-G87 PolarHBondContact O-N 3.01Å; A83-Q88 WeakPolarHBondContact CA-O 3.34Å
84L91.3Very high93.4Very high8 Ų858.5 Ų58.54%0.04231%0.31CS..Hα-helixtrans-67.6-38.4-175.2-67.5170.4000114W23 M30 F31 A80 L81 D327W23-L84 PolarHBondContact NE1-O 3.23Å; M30-L84 HydrophobicContact CE-CD1 4.32Å; M30-L84 HydrophobicContact CE-CD2 3.64Å; M30-L84 HydrophobicContact CE-CG 3.67Å; F31-L84 HydrophobicContact CE2-CD1 4.1Å; F31-L84 HydrophobicContact CE2-CD2 4.49Å; F31-L84 HydrophobicContact CZ-CD1 4.02Å; A80-L84 VanDerWaalsContact O-CG 3.29Å; A80-L84 WeakPolarHBondContact O-CG 3.09Å; A80-L84 PolarHBondContact O-N 3.39Å; L81-L84 HydrophobicContact CD2-CD1 4.47Å; L81-L84 PolarHBondContact O-N 2.86Å; L84-D327 HydrophobicContact CD1-CB 4.23Å
85D90Very high93.5Very high79 Ų7956.6 Ų56.642%0.42230%0.3SS..Hα-helixtrans-109.6-21-168.7-59.6-22.1000113.2L81 R329 R334L81-D85 VanDerWaalsContact O-CB 3.31Å; L81-D85 WeakPolarHBondContact O-CB 3.48Å; L81-D85 PolarHBondContact O-N 2.76Å; D85-R329 IonicContact OD1-NH2 3.61Å; D85-R329 PolarHBondContact OD1-NH2 3.4Å; D85-R334 IonicContact OD1-CZ 2.74Å; D85-R334 IonicContact OD1-NH1 2.8Å; D85-R334 PolarHBondContact OD1-NH1 3.11Å; D85-R334 IonicContact OD1-NH2 3.97Å; D85-R334 PolarHBondContact OD1-NH2 3.45Å; D85-R334 IonicContact OD2-CZ 2.68Å; D85-R334 IonicContact OD2-NH1 2.88Å; D85-R334 PolarHBondContact OD2-NH1 3.16Å; D85-R334 IonicContact OD2-NH2 3.18Å; D85-R334 PolarHBondContact OD2-NH2 2.87Å
86R86.4Confident93.6Very high172 Ų17256 Ų5665%0.64930%0.295SS*.Hα-helixtrans-119.35.9-175.1-48.4-178.3-175.8-174-2.2113.4R82 Q88R82-R86 CarbonylContact O-C 3.29Å; R82-R86 WeakPolarHBondContact O-CA 3.31Å; R82-R86 VanDerWaalsContact O-CB 3.28Å; R82-R86 WeakPolarHBondContact O-CB 3.46Å; R82-R86 PolarHBondContact O-N 3.36Å; R82-R86 VanDerWaalsContact O-N 3.14Å; R86-Q88 HydrophobicContact CB-CG 4.19Å; R86-Q88 PolarHBondContact O-N 2.8Å
87G83Confident93.7Very high74 Ų7450.7 Ų50.776%0.76327%0.272SS*.  trans61.523.1179.200000113.8A83A83-G87 PolarHBondContact O-N 3.01Å
88Q87.9Confident93.7Very high96 Ų9650.5 Ų50.545%0.44927%0.271SS..PPolyproline II helixtrans-74.5165.5176.8-64.3-168.8-3.200111.3R82 A83 R86R82-Q88 HydrophobicContact CB-CB 4.34Å; R82-Q88 HydrophobicContact CB-CG 4.42Å; R82-Q88 VanDerWaalsContact CD-OE1 3.26Å; R82-Q88 PolarHBondContact O-N 3.34Å; A83-Q88 WeakPolarHBondContact CA-O 3.34Å; R86-Q88 HydrophobicContact CB-CG 4.19Å; R86-Q88 PolarHBondContact O-N 2.8Å
89A89.3Confident93.8Very high92 Ų9247.4 Ų47.476%0.7626%0.257SS*.PPolyproline II helixtrans-57.8143.3175.500000111.3
90K91.5Very high93.8Very high91 Ų9145.2 Ų45.240%0.39625%0.247SC..PPolyproline II helixtrans-62.1139.6176.2-52.7-176.7-155.5-165.30109.4H25 H26 M30H25-K90 PolarHBondContact O-NZ 2.96Å; H26-K90 VanDerWaalsContact O-CD 3.23Å; H26-K90 WeakPolarHBondContact O-CD 3.4Å; H26-K90 WeakPolarHBondContact O-CE 3.35Å; H26-K90 PolarHBondContact O-NZ 3.39Å; M30-K90 HydrophobicContact CG-CB 4.29Å; M30-K90 HydrophobicContact CG-CD 4.14Å; M30-K90 HydrophobicContact CG-CG 4.31Å; M30-K90 HydrophobicContact SD-CB 4.11Å; M30-K90 HydrophobicContact SD-CG 4.28Å
91P94.3Very high93.9Very high20 Ų2045.9 Ų45.913%0.1325%0.249CC..PPolyproline II helixtrans-57150.5168.224.8-32.1000110.4M30 P75 E79 R93M30-P91 WeakPolarHBondContact SD-CD 3.47Å; M30-P91 HydrophobicContact SD-CG 4Å; P75-P91 HydrophobicContact CB-CB 3.87Å; P75-P91 HydrophobicContact CB-CG 3.35Å; P75-P91 HydrophobicContact CG-CG 3.92Å; E79-P91 HydrophobicContact CB-CB 4.11Å; E79-P91 HydrophobicContact CB-CG 4.31Å; P91-R93 PolarHBondContact O-N 2.71Å
92P95.1Very high93.9Very high84 Ų8445.4 Ų45.455%0.54525%0.248SC..PPolyproline II helixtrans-53.9130.5175.1-24.533.9000111P116P92-P116 HydrophobicContact CB-CB 4.22Å
93R97.5Very high93.9Very high48 Ų4845.3 Ų45.318%0.18125%0.254CS..PPolyproline II helixtrans-76.5131.5176.8-171.7172.1165.3822.4109.4P29 A32 D33 E38 L72 P91 P116 L117P29-R93 PolarHBondContact O-NH1 2.93Å; A32-R93 VanDerWaalsContact O-CZ 3.25Å; A32-R93 PolarHBondContact O-NH1 3Å; A32-R93 PolarHBondContact O-NH2 3.35Å; D33-R93 PolarHBondContact O-NH2 3.5Å; E38-R93 VanDerWaalsContact OE1-CD 3.29Å; E38-R93 WeakPolarHBondContact OE1-CD 3.26Å; E38-R93 IonicContact OE1-CZ 3.91Å; E38-R93 IonicContact OE1-NE 2.81Å; E38-R93 PolarHBondContact OE1-NE 2.89Å; E38-R93 IonicContact OE1-NH2 3.9Å; E38-R93 IonicContact OE2-CZ 3.44Å; E38-R93 IonicContact OE2-NE 2.83Å; E38-R93 PolarHBondContact OE2-NE 3.11Å; E38-R93 IonicContact OE2-NH2 3.97Å; E38-R93 PolarHBondContact OE2-NH2 2.85Å; L72-R93 HydrophobicContact CD1-CG 4.12Å; L72-R93 VanDerWaalsContact CD1-NH1 3.28Å; P91-R93 PolarHBondContact O-N 2.71Å; R93-P116 CarbonylContact O-C 3.6Å; R93-P116 WeakPolarHBondContact O-CA 3.44Å; R93-L117 HydrophobicContact CB-CB 4.23Å; R93-L117 HydrophobicContact CG-CB 4.22Å; R93-L117 HydrophobicContact CG-CD1 4.22Å; R93-L117 PolarHBondContact O-N 3.02Å
94Q98.5Very high94Very high50 Ų5048.2 Ų48.223%0.23427%0.265CS..EExtended strand (participates in β ladder)trans-135.9160-173.7-64.2175.5-64.700110.7H73 I113 V114H73-Q94 HydrophobicContact CB-CB 4.09Å; H73-Q94 PolarHBondContact N-O 2.91Å; Q94-I113 HydrophobicContact CB-CG2 3.73Å; Q94-I113 HydrophobicContact CG-CG2 4.12Å; Q94-V114 CarbonylContact C-O 3.59Å; Q94-V114 WeakPolarHBondContact CA-O 3.15Å
95A98.8Very high94Very high0 Ų054.8 Ų54.80%031%0.306CS..EExtended strand (participates in β ladder)trans-115.6141.9174.200000111.1L34 I42 E71 V97 I113 V114 L117L34-A95 HydrophobicContact CD1-CB 3.79Å; L34-A95 HydrophobicContact CD2-CB 4.14Å; I42-A95 HydrophobicContact CD1-CB 3.36Å; I42-A95 HydrophobicContact CG1-CB 4.28Å; E71-A95 CarbonylContact O-C 3.56Å; E71-A95 WeakPolarHBondContact O-CA 3.46Å; A95-V97 HydrophobicContact CB-CG2 4.24Å; A95-I113 CarbonylContact O-C 3.54Å; A95-I113 WeakPolarHBondContact O-CA 3.46Å; A95-V114 PolarHBondContact N-O 2.83Å; A95-V114 PolarHBondContact O-N 3.03Å; A95-L117 HydrophobicContact CB-CD1 4.19Å
96R98.6Very high94.1Very high5 Ų556 Ų562%0.01932%0.316CS..EExtended strand (participates in β ladder)trans-85.7122.7162.2176.6-169.2176.9-138.91.2107E71 H73 E111 Y112 I113 R126E71-R96 HydrophobicContact CG-CB 4.11Å; E71-R96 PolarHBondContact N-O 3.24Å; E71-R96 PolarHBondContact O-N 3.22Å; E71-R96 WeakPolarHBondContact OE1-CD 3.41Å; E71-R96 IonicContact OE1-CZ 3.53Å; E71-R96 IonicContact OE1-NE 2.99Å; E71-R96 IonicContact OE1-NH1 3.7Å; E71-R96 PolarHBondContact OE1-NH1 3.44Å; H73-R96 HydrophobicContact CB-CB 4.36Å; R96-E111 IonicContact CZ-OE1 3.85Å; R96-E111 IonicContact CZ-OE2 3.21Å; R96-E111 VanDerWaalsContact NE-CD 3.34Å; R96-E111 IonicContact NE-OE1 2.76Å; R96-E111 PolarHBondContact NE-OE1 3.15Å; R96-E111 IonicContact NE-OE2 3.41Å; R96-E111 PolarHBondContact NE-OE2 3.13Å; R96-E111 IonicContact NH2-OE1 2.7Å; R96-E111 PolarHBondContact NH2-OE1 3.43Å; R96-E111 IonicContact NH2-OE2 2.77Å; R96-Y112 CarbonylContact C-O 3.57Å; R96-Y112 WeakPolarHBondContact CA-O 3.1Å; R96-I113 HydrophobicContact CB-CD1 4.25Å; R96-R126 VanDerWaalsContact NE-NH1 3.18Å
97V98.7Very high94.6Very high0 Ų049.7 Ų49.70%030%0.298CS..EExtended strand (participates in β ladder)trans-122.2131.9177.7-173.90000109I42 L46 I67 L69 M70 A95 I99 E111 Y112 V114I42-V97 HydrophobicContact CG2-CG2 3.63Å; L46-V97 HydrophobicContact CD1-CB 4.27Å; L46-V97 HydrophobicContact CD1-CG1 3.67Å; L46-V97 HydrophobicContact CD1-CG2 4.24Å; I67-V97 HydrophobicContact CG2-CG1 3.63Å; L69-V97 CarbonylContact O-C 3.54Å; L69-V97 VanDerWaalsContact O-CA 3.32Å; L69-V97 WeakPolarHBondContact O-CA 3.49Å; M70-V97 HydrophobicContact CG-CG1 4.19Å; M70-V97 HydrophobicContact CG-CG2 4.25Å; A95-V97 HydrophobicContact CB-CG2 4.24Å; V97-I99 HydrophobicContact CG1-CG1 4.16Å; V97-E111 CarbonylContact O-C 3.07Å; V97-E111 WeakPolarHBondContact O-CA 3.31Å; V97-Y112 PolarHBondContact N-O 2.64Å; V97-Y112 PolarHBondContact O-N 3.23Å; V97-V114 HydrophobicContact CB-CG2 4.18Å; V97-V114 HydrophobicContact CG2-CB 4.23Å; V97-V114 HydrophobicContact CG2-CG2 3.67Å
98I98.3Very high95.1Very high0 Ų048.7 Ų48.70%028%0.275CS..EExtended strand (participates in β ladder)trans-108.2124.4177.5-51.6-177.7000107.9L68 L69 I109 E111 I627 F628L68-I98 HydrophobicContact CB-CB 4.43Å; L68-I98 HydrophobicContact CB-CG2 4.39Å; L68-I98 HydrophobicContact CD2-CG2 4.16Å; L68-I98 PolarHBondContact N-O 3.44Å; L69-I98 HydrophobicContact CB-CB 4.11Å; L69-I98 HydrophobicContact CB-CD1 3.99Å; L69-I98 HydrophobicContact CB-CG1 4.07Å; L69-I98 HydrophobicContact CD2-CD1 3.59Å; L69-I98 HydrophobicContact CD2-CG1 4.23Å; L69-I98 HydrophobicContact CG-CD1 4.41Å; L69-I98 PolarHBondContact N-O 3.1Å; L69-I98 PolarHBondContact O-N 3.47Å; I98-I109 HydrophobicContact CG2-CD1 3.71Å; I98-I109 HydrophobicContact CG2-CG1 3.63Å; I98-E111 HydrophobicContact CG1-CG 4.17Å; I98-I627 HydrophobicContact CD1-CD1 3.29Å; I98-I627 HydrophobicContact CD1-CG1 4.24Å; I98-F628 HydrophobicContact CD1-CZ 4.14Å; I98-F628 HydrophobicContact CG2-CE1 4.33Å; I98-F628 HydrophobicContact CG2-CZ 4.19Å
99I97.9Very high95.5Very high0 Ų044.5 Ų44.50%026%0.255CS..EExtended strand (participates in β ladder)trans-117129.1179.1-56.1-177.5000108.6L46 M52 L54 S66 I67 V97 F101 I109 T110 Y112L46-I99 HydrophobicContact CD1-CD1 4.34Å; M52-I99 HydrophobicContact SD-CD1 4Å; L54-I99 HydrophobicContact CD1-CD1 4.49Å; L54-I99 HydrophobicContact CD2-CD1 4.37Å; L54-I99 HydrophobicContact CD2-CG2 3.63Å; S66-I99 WeakPolarHBondContact O-CA 3.47Å; S66-I99 WeakPolarHBondContact O-CG2 3.38Å; I67-I99 HydrophobicContact CG1-CG1 4.47Å; V97-I99 HydrophobicContact CG1-CG1 4.16Å; I99-F101 HydrophobicContact CB-CD2 4.44Å; I99-F101 HydrophobicContact CB-CE2 3.88Å; I99-F101 HydrophobicContact CB-CZ 4.16Å; I99-F101 HydrophobicContact CD1-CZ 4.48Å; I99-F101 HydrophobicContact CG2-CD1 4.33Å; I99-F101 HydrophobicContact CG2-CD2 4Å; I99-F101 HydrophobicContact CG2-CE1 3.95Å; I99-F101 HydrophobicContact CG2-CE2 3.62Å; I99-F101 HydrophobicContact CG2-CG 4.35Å; I99-F101 HydrophobicContact CG2-CZ 3.58Å; I99-I109 WeakPolarHBondContact O-CA 3.45Å; I99-T110 PolarHBondContact N-O 2.72Å; I99-T110 PolarHBondContact O-N 2.98Å; I99-Y112 HydrophobicContact CB-CD2 4.47Å; I99-Y112 HydrophobicContact CB-CE2 4.22Å; I99-Y112 HydrophobicContact CD1-CD2 3.77Å; I99-Y112 HydrophobicContact CD1-CE2 3.78Å; I99-Y112 HydrophobicContact CG1-CD2 4.03Å; I99-Y112 HydrophobicContact CG1-CE2 4.16Å
100Q96.6Very high95.8Very high9 Ų941.3 Ų41.34%0.04223%0.226CC..EExtended strand (participates in β ladder)trans-90.3124.2168.7-68.3176.5-6.600108.3N65 S66 L68 I109 F136N65-Q100 CarbonylContact C-O 3.57Å; N65-Q100 WeakPolarHBondContact CA-O 3.39Å; S66-Q100 PolarHBondContact N-O 3.17Å; S66-Q100 PolarHBondContact O-N 3Å; L68-Q100 HydrophobicContact CB-CG 4.15Å; L68-Q100 HydrophobicContact CD2-CG 4.33Å; Q100-I109 HydrophobicContact CG-CD1 3.92Å; Q100-I109 HydrophobicContact CG-CG1 4.3Å; Q100-F136 HydrophobicContact CB-CE2 4.31Å
101F96.7Very high96.1Very high14 Ų1437.2 Ų37.26%0.06121%0.208CC..EExtended strand (participates in β ladder)trans-107.983174.9-68.2-82000110M52 N65 I99 Q104 P107 N108 Y112M52-F101 HydrophobicContact CB-CE1 4.38Å; N65-F101 HydrophobicContact CB-CD1 4.03Å; N65-F101 VanDerWaalsContact OD1-CA 3.3Å; N65-F101 WeakPolarHBondContact OD1-CA 3.26Å; I99-F101 HydrophobicContact CB-CD2 4.44Å; I99-F101 HydrophobicContact CB-CE2 3.88Å; I99-F101 HydrophobicContact CB-CZ 4.16Å; I99-F101 HydrophobicContact CD1-CZ 4.48Å; I99-F101 HydrophobicContact CG2-CD1 4.33Å; I99-F101 HydrophobicContact CG2-CD2 4Å; I99-F101 HydrophobicContact CG2-CE1 3.95Å; I99-F101 HydrophobicContact CG2-CE2 3.62Å; I99-F101 HydrophobicContact CG2-CG 4.35Å; I99-F101 HydrophobicContact CG2-CZ 3.58Å; F101-Q104 HydrophobicContact CB-CG 4.4Å; F101-P107 WeakPolarHBondContact O-CA 3.47Å; F101-N108 WeakPolarHBondContact CD2-OD1 3.2Å; F101-N108 PolarHBondContact N-O 3.05Å; F101-N108 PolarHBondContact O-N 2.78Å; F101-N108 VanDerWaalsContact O-N 3.13Å; F101-Y112 AromaticContact CE2-CE2 3.93Å; F101-Y112 HydrophobicContact CE2-CE2 3.93Å; F101-Y112 HydrophobicContact CZ-CE2 4.2Å
102G95.3Very high96.2Very high3 Ų337.5 Ų37.53%0.03121%0.207CC..  trans-87.8-19.8177.700000114.1R64 N65 Q104 L225R64-G102 VanDerWaalsContact O-CA 3.27Å; R64-G102 WeakPolarHBondContact O-CA 3.41Å; R64-G102 PolarHBondContact O-N 2.94Å; N65-G102 PolarHBondContact OD1-N 3.18Å; G102-Q104 VanDerWaalsContact C-N 3.33Å; G102-Q104 PolarHBondContact O-N 3.48Å; G102-L225 WeakPolarHBondContact O-CD1 3.28Å
103N94.6Very high96.4Very high90 Ų9033.8 Ų33.848%0.48118%0.183SC..SBendtrans-93.257.7-177.6-166.210.5000112.4K63 N65K63-N103 WeakPolarHBondContact O-CB 3.29Å; N65-N103 WeakPolarHBondContact OD1-CB 3.35Å; N65-N103 PolarHBondContact OD1-N 3.26Å
104Q93.8Very high96.5Very high78 Ų7831.5 Ų31.536%0.36417%0.174SC..SBendtrans-155.4166.3177.858.7-175.250.400111.4F101 G102 T106 N108F101-Q104 HydrophobicContact CB-CG 4.4Å; G102-Q104 VanDerWaalsContact C-N 3.33Å; G102-Q104 PolarHBondContact O-N 3.48Å; Q104-T106 PolarHBondContact NE2-O 3.19Å; Q104-T106 PolarHBondContact O-N 2.96Å; Q104-N108 PolarHBondContact NE2-ND2 3.39Å
105T91.2Very high96.4Very high146 Ų14629.1 Ų29.190%0.89616%0.163SC*.SBendtrans-60.6-32.2-17651.60000113.6
106T93.4Very high96.4Very high104 Ų10432 Ų3264%0.63818%0.182SC*.SBendtrans-129.792.1177-52.10000107.8Q104Q104-T106 PolarHBondContact NE2-O 3.19Å; Q104-T106 PolarHBondContact O-N 2.96Å
107P95.4Very high96.3Very high40 Ų4032.7 Ų32.726%0.2619%0.186SC..  trans-52.7143.6179.9-29.337000112.2F101 F136 L225F101-P107 WeakPolarHBondContact O-CA 3.47Å; P107-F136 HydrophobicContact CB-CB 4.09Å; P107-F136 HydrophobicContact CB-CD1 3.58Å; P107-F136 HydrophobicContact CB-CD2 3.77Å; P107-F136 HydrophobicContact CB-CE1 3.88Å; P107-F136 HydrophobicContact CB-CE2 4.03Å; P107-F136 HydrophobicContact CB-CG 3.51Å; P107-F136 HydrophobicContact CB-CZ 4.08Å; P107-L225 HydrophobicContact CB-CD1 4.11Å; P107-L225 HydrophobicContact CG-CD1 3.56Å
108N94.5Very high96.3Very high52 Ų5236.7 Ų36.728%0.27821%0.212SC..EExtended strand (participates in β ladder)trans-149.1166.817675.644.7000111.9F101 Q104 T110 F136F101-N108 WeakPolarHBondContact CD2-OD1 3.2Å; F101-N108 PolarHBondContact N-O 3.05Å; F101-N108 PolarHBondContact O-N 2.78Å; F101-N108 VanDerWaalsContact O-N 3.13Å; Q104-N108 PolarHBondContact NE2-ND2 3.39Å; N108-T110 PolarHBondContact OD1-OG1 2.95Å; N108-T110 VanDerWaalsContact OD1-OG1 3.07Å; N108-F136 VanDerWaalsContact C-CD2 3.48Å; N108-F136 WeakPolarHBondContact O-CD2 3.49Å
109I95.5Very high96.2Very high8 Ų840.2 Ų40.24%0.04124%0.236CC..EExtended strand (participates in β ladder)trans-121.6129.5171.6-171.3162.6000108.4L68 I98 I99 Q100 V134 R139 F628L68-I109 HydrophobicContact CD2-CD1 4.07Å; I98-I109 HydrophobicContact CG2-CD1 3.71Å; I98-I109 HydrophobicContact CG2-CG1 3.63Å; I99-I109 WeakPolarHBondContact O-CA 3.45Å; Q100-I109 HydrophobicContact CG-CD1 3.92Å; Q100-I109 HydrophobicContact CG-CG1 4.3Å; I109-V134 HydrophobicContact CG2-CB 3.61Å; I109-V134 HydrophobicContact CG2-CG1 3.34Å; I109-R139 HydrophobicContact CD1-CB 3.8Å; I109-F628 HydrophobicContact CD1-CD1 4.21Å; I109-F628 HydrophobicContact CD1-CE1 3.47Å; I109-F628 VanDerWaalsContact CD1-CE1 3.47Å; I109-F628 HydrophobicContact CD1-CZ 4.25Å; I109-F628 HydrophobicContact CG1-CE1 4.12Å; I109-F628 HydrophobicContact CG1-CZ 4.47Å; I109-F628 HydrophobicContact CG2-CE1 4.41Å
110T95.7Very high96.2Very high25 Ų2541 Ų4115%0.15324%0.241CC..EExtended strand (participates in β ladder)trans-128.7134.7-173.6-58.10000110.5I99 N108 Y112 V125I99-T110 PolarHBondContact N-O 2.72Å; I99-T110 PolarHBondContact O-N 2.98Å; N108-T110 PolarHBondContact OD1-OG1 2.95Å; N108-T110 VanDerWaalsContact OD1-OG1 3.07Å; T110-Y112 HydrophobicContact CG2-CD2 4.14Å; T110-Y112 HydrophobicContact CG2-CE1 4.24Å; T110-Y112 HydrophobicContact CG2-CE2 3.54Å; T110-V125 HydrophobicContact CG2-CG1 3.85Å; T110-V125 HydrophobicContact CG2-CG2 4.19Å
111E97.1Very high96.3Very high5 Ų550.4 Ų50.42%0.02328%0.277CS..EExtended strand (participates in β ladder)trans-93.1134.8170.6-61.1-160.7-171.800110.7R96 V97 I98 R126 F128 F628R96-E111 IonicContact CZ-OE1 3.85Å; R96-E111 IonicContact CZ-OE2 3.21Å; R96-E111 VanDerWaalsContact NE-CD 3.34Å; R96-E111 IonicContact NE-OE1 2.76Å; R96-E111 PolarHBondContact NE-OE1 3.15Å; R96-E111 IonicContact NE-OE2 3.41Å; R96-E111 PolarHBondContact NE-OE2 3.13Å; R96-E111 IonicContact NH2-OE1 2.7Å; R96-E111 PolarHBondContact NH2-OE1 3.43Å; R96-E111 IonicContact NH2-OE2 2.77Å; V97-E111 CarbonylContact O-C 3.07Å; V97-E111 WeakPolarHBondContact O-CA 3.31Å; I98-E111 HydrophobicContact CG1-CG 4.17Å; E111-R126 HydrophobicContact CB-CB 3.93Å; E111-R126 PolarHBondContact O-N 3.14Å; E111-R126 WeakPolarHBondContact OE2-CD 3.47Å; E111-R126 IonicContact OE2-CZ 3.24Å; E111-R126 IonicContact OE2-NE 3.64Å; E111-R126 IonicContact OE2-NH1 3.96Å; E111-R126 PolarHBondContact OE2-NH1 3.41Å; E111-F128 WeakPolarHBondContact OE1-CZ 3.34Å; E111-F628 HydrophobicContact CG-CE2 4.47Å; E111-F628 HydrophobicContact CG-CZ 4.33Å; E111-F628 VanDerWaalsContact OE1-CE2 3.24Å; E111-F628 WeakPolarHBondContact OE1-CE2 3.37Å
112Y98Very high96.3Very high26 Ų2652.7 Ų52.710%0.10230%0.295CS..EExtended strand (participates in β ladder)trans-119.3142.1174.3-65.5-88000110.9M52 R96 V97 I99 F101 T110 H123 E124 V125M52-Y112 HydrophobicContact CE-CE1 4.42Å; R96-Y112 CarbonylContact C-O 3.57Å; R96-Y112 WeakPolarHBondContact CA-O 3.1Å; V97-Y112 PolarHBondContact N-O 2.64Å; V97-Y112 PolarHBondContact O-N 3.23Å; I99-Y112 HydrophobicContact CB-CD2 4.47Å; I99-Y112 HydrophobicContact CB-CE2 4.22Å; I99-Y112 HydrophobicContact CD1-CD2 3.77Å; I99-Y112 HydrophobicContact CD1-CE2 3.78Å; I99-Y112 HydrophobicContact CG1-CD2 4.03Å; I99-Y112 HydrophobicContact CG1-CE2 4.16Å; F101-Y112 AromaticContact CE2-CE2 3.93Å; F101-Y112 HydrophobicContact CE2-CE2 3.93Å; F101-Y112 HydrophobicContact CZ-CE2 4.2Å; T110-Y112 HydrophobicContact CG2-CD2 4.14Å; T110-Y112 HydrophobicContact CG2-CE1 4.24Å; T110-Y112 HydrophobicContact CG2-CE2 3.54Å; Y112-H123 HydrophobicContact CD1-CB 4.4Å; Y112-H123 AromaticContact CD1-CD2 3.7Å; Y112-H123 AromaticContact CE1-CD2 3.82Å; Y112-E124 CarbonylContact C-O 3.59Å; Y112-E124 WeakPolarHBondContact CA-O 3.42Å; Y112-V125 HydrophobicContact CD1-CG2 4.06Å; Y112-V125 HydrophobicContact CE1-CG2 3.57Å
113I98.4Very high96.5Very high6 Ų656 Ų563%0.03131%0.309CS..EExtended strand (participates in β ladder)trans-95.8116.9161.2-54.6-49.1000107.8H73 Q94 A95 R96 H123 E124 R126H73-I113 HydrophobicContact CB-CD1 4.11Å; H73-I113 HydrophobicContact CB-CG2 4.41Å; H73-I113 WeakPolarHBondContact ND1-CD1 3.41Å; Q94-I113 HydrophobicContact CB-CG2 3.73Å; Q94-I113 HydrophobicContact CG-CG2 4.12Å; A95-I113 CarbonylContact O-C 3.54Å; A95-I113 WeakPolarHBondContact O-CA 3.46Å; R96-I113 HydrophobicContact CB-CD1 4.25Å; I113-H123 CarbonylContact O-C 3.59Å; I113-H123 VanDerWaalsContact O-CA 3.27Å; I113-H123 WeakPolarHBondContact O-CA 3.35Å; I113-E124 HydrophobicContact CB-CG 3.78Å; I113-E124 HydrophobicContact CG1-CG 4.43Å; I113-E124 PolarHBondContact N-O 3.36Å; I113-E124 PolarHBondContact O-N 3.48Å; I113-R126 HydrophobicContact CD1-CB 4.33Å; I113-R126 HydrophobicContact CG1-CB 4.23Å
114V98.8Very high96.6Very high0 Ų057.1 Ų57.10%031%0.311CS..EExtended strand (participates in β ladder)trans-110.5132.5-176.1-176.30000109.5I42 Y45 L46 Q94 A95 V97 P120 H123I42-V114 HydrophobicContact CG1-CG1 4.47Å; I42-V114 HydrophobicContact CG2-CG1 4.28Å; Y45-V114 HydrophobicContact CD1-CG1 3.78Å; Y45-V114 HydrophobicContact CE1-CG1 3.85Å; L46-V114 HydrophobicContact CD1-CG2 4.33Å; L46-V114 HydrophobicContact CD2-CG2 4.1Å; Q94-V114 CarbonylContact C-O 3.59Å; Q94-V114 WeakPolarHBondContact CA-O 3.15Å; A95-V114 PolarHBondContact N-O 2.83Å; A95-V114 PolarHBondContact O-N 3.03Å; V97-V114 HydrophobicContact CB-CG2 4.18Å; V97-V114 HydrophobicContact CG2-CB 4.23Å; V97-V114 HydrophobicContact CG2-CG2 3.67Å; V114-P120 HydrophobicContact CG1-CB 3.74Å; V114-H123 HydrophobicContact CG2-CB 4.05Å
115G97.8Very high96.7Very high1 Ų157.4 Ų57.41%0.0132%0.318CS..EExtended strand (participates in β ladder)trans178.2-169.4177.500000114.1R121 S122G115-R121 PolarHBondContact O-N 2.77Å; G115-R121 VanDerWaalsContact O-N 3.11Å; G115-S122 PolarHBondContact N-O 2.9Å; G115-S122 PolarHBondContact O-N 2.81Å; G115-S122 VanDerWaalsContact O-O 3.04Å; G115-S122 PolarHBondContact O-OG 3.31Å
116P97.8Very high96.7Very high60 Ų6053.6 Ų53.639%0.3929%0.287SS..SBendcis-71.3152.3-11.231.9-35.5000112P92 R93 S119 P120P92-P116 HydrophobicContact CB-CB 4.22Å; R93-P116 CarbonylContact O-C 3.6Å; R93-P116 WeakPolarHBondContact O-CA 3.44Å; P116-S119 CarbonylContact O-C 3.59Å; P116-S119 PolarHBondContact O-N 2.96Å; P116-S119 VanDerWaalsContact O-O 3.05Å; P116-P120 VanDerWaalsContact O-CA 3.28Å; P116-P120 WeakPolarHBondContact O-CA 3.3Å
117L98.1Very high96.5Very high19 Ų1952.8 Ų52.810%0.09928%0.282CS..SBendtrans-89.4150.3175-63.6175.6000111.4L34 E38 I42 R93 A95 P120L34-L117 HydrophobicContact CD2-CD1 3.45Å; L34-L117 VanDerWaalsContact CD2-CD1 3.45Å; E38-L117 HydrophobicContact CB-CD1 4.33Å; E38-L117 HydrophobicContact CB-CD2 4.45Å; E38-L117 HydrophobicContact CG-CB 4.33Å; E38-L117 HydrophobicContact CG-CD1 4.37Å; I42-L117 HydrophobicContact CD1-CD1 4.22Å; I42-L117 HydrophobicContact CD1-CD2 3.78Å; I42-L117 HydrophobicContact CG1-CD2 3.58Å; R93-L117 HydrophobicContact CB-CB 4.23Å; R93-L117 HydrophobicContact CG-CB 4.22Å; R93-L117 HydrophobicContact CG-CD1 4.22Å; R93-L117 PolarHBondContact O-N 3.02Å; A95-L117 HydrophobicContact CB-CD1 4.19Å; L117-P120 HydrophobicContact CD2-CB 4.5Å
118P96.8Very high96.1Very high84 Ų8452 Ų5255%0.54528%0.275SS..SBendcis-87.8-0.29.135.7-37.5000115.4E38 A41 P120E38-P118 HydrophobicContact CG-CB 4.24Å; A41-P118 WeakPolarHBondContact CB-O 3.22Å; P118-P120 VanDerWaalsContact O-CD 3.28Å; P118-P120 WeakPolarHBondContact O-CD 3.39Å
119S97.6Very high95.4Very high74 Ų7456.4 Ų56.452%0.51729%0.292SS..SBendtrans-116.780-177.4-57.60000110.7P116P116-S119 CarbonylContact O-C 3.59Å; P116-S119 PolarHBondContact O-N 2.96Å; P116-S119 VanDerWaalsContact O-O 3.05Å
120P98Very high94.6Very high16 Ų1659.3 Ų59.310%0.10432%0.324CS..  trans-61.8139.2-174.926.1-34.2000111.6A41 Y45 V114 P116 L117 P118A41-P120 HydrophobicContact CB-CG 4.36Å; Y45-P120 HydrophobicContact CD1-CB 4.08Å; Y45-P120 HydrophobicContact CD1-CG 4.39Å; Y45-P120 WeakPolarHBondContact CD2-O 3.42Å; Y45-P120 HydrophobicContact CG-CB 4.06Å; Y45-P120 HydrophobicContact CG-CG 4.04Å; V114-P120 HydrophobicContact CG1-CB 3.74Å; P116-P120 VanDerWaalsContact O-CA 3.28Å; P116-P120 WeakPolarHBondContact O-CA 3.3Å; L117-P120 HydrophobicContact CD2-CB 4.5Å; P118-P120 VanDerWaalsContact O-CD 3.28Å; P118-P120 WeakPolarHBondContact O-CD 3.39Å
121R97.6Very high93.9Very high207 Ų20766.3 Ų66.378%0.78135%0.352SS*.  trans-136.1-13.4-178.7-65.1179.9-174.2-176.1-0.2113.6Y45 G115Y45-R121 PolarHBondContact OH-O 3.47Å; G115-R121 PolarHBondContact O-N 2.77Å; G115-R121 VanDerWaalsContact O-N 3.11Å
122S97.8Very high92.9Very high63 Ų6373.2 Ų73.244%0.44138%0.382SS..EExtended strand (participates in β ladder)trans-139.8152-179560000110.6Y45 G115Y45-S122 WeakPolarHBondContact OH-CA 3.31Å; Y45-S122 PolarHBondContact OH-N 3.22Å; G115-S122 PolarHBondContact N-O 2.9Å; G115-S122 PolarHBondContact O-N 2.81Å; G115-S122 VanDerWaalsContact O-O 3.04Å; G115-S122 PolarHBondContact O-OG 3.31Å
123H97.9Very high92Very high71 Ų7177.2 Ų77.233%0.32941%0.411SS..EExtended strand (participates in β ladder)trans-136.1144.3169.561.5-86.4000109.1Y45 I49 M52 Y112 I113 V114Y45-H123 HydrophobicContact CE1-CB 4.16Å; Y45-H123 AromaticContact CE1-ND1 3.86Å; Y45-H123 AromaticContact CZ-ND1 3.74Å; Y45-H123 PolarHBondContact OH-N 3.47Å; Y45-H123 PolarHBondContact OH-ND1 2.92Å; I49-H123 VanDerWaalsContact CD1-CE1 3.47Å; I49-H123 WeakPolarHBondContact CD1-CE1 3.37Å; I49-H123 WeakPolarHBondContact CD1-ND1 3.33Å; M52-H123 WeakPolarHBondContact CE-NE2 3.26Å; Y112-H123 HydrophobicContact CD1-CB 4.4Å; Y112-H123 AromaticContact CD1-CD2 3.7Å; Y112-H123 AromaticContact CE1-CD2 3.82Å; I113-H123 CarbonylContact O-C 3.59Å; I113-H123 VanDerWaalsContact O-CA 3.27Å; I113-H123 WeakPolarHBondContact O-CA 3.35Å; V114-H123 HydrophobicContact CG2-CB 4.05Å
124E97.1Very high91.7Very high115 Ų11577.8 Ų77.854%0.53742%0.415SS..EExtended strand (participates in β ladder)trans-130.9145175.262-180-179.100110.6Y112 I113 R126Y112-E124 CarbonylContact C-O 3.59Å; Y112-E124 WeakPolarHBondContact CA-O 3.42Å; I113-E124 HydrophobicContact CB-CG 3.78Å; I113-E124 HydrophobicContact CG1-CG 4.43Å; I113-E124 PolarHBondContact N-O 3.36Å; I113-E124 PolarHBondContact O-N 3.48Å; E124-R126 PolarHBondContact O-N 3.49Å
125V95.5Very high91.3Very high84 Ų8481.9 Ų81.951%0.50943%0.434SS..EExtended strand (participates in β ladder)trans-73.2126.7177.3176.50000109.5T110 Y112 T127T110-V125 HydrophobicContact CG2-CG1 3.85Å; T110-V125 HydrophobicContact CG2-CG2 4.19Å; Y112-V125 HydrophobicContact CD1-CG2 4.06Å; Y112-V125 HydrophobicContact CE1-CG2 3.57Å; V125-T127 HydrophobicContact CG1-CG2 4.19Å
126R92.7Very high91.2Very high65 Ų6582.3 Ų82.325%0.24544%0.436CS..EExtended strand (participates in β ladder)trans-89.1125.1170.5179.1177.9178.6-145.25.7109.6R96 E111 I113 E124R96-R126 VanDerWaalsContact NE-NH1 3.18Å; E111-R126 HydrophobicContact CB-CB 3.93Å; E111-R126 PolarHBondContact O-N 3.14Å; E111-R126 WeakPolarHBondContact OE2-CD 3.47Å; E111-R126 IonicContact OE2-CZ 3.24Å; E111-R126 IonicContact OE2-NE 3.64Å; E111-R126 IonicContact OE2-NH1 3.96Å; E111-R126 PolarHBondContact OE2-NH1 3.41Å; I113-R126 HydrophobicContact CD1-CB 4.33Å; I113-R126 HydrophobicContact CG1-CB 4.23Å; E124-R126 PolarHBondContact O-N 3.49Å
127T88.9Confident91.2Very high87 Ų8781.4 Ų81.453%0.53443%0.426SS..  trans-112146.5178.660.80000112V125V125-T127 HydrophobicContact CG1-CG2 4.19Å
128F87.2Confident91.1Very high25 Ų2580.7 Ų80.711%0.1142%0.423CS..  trans-77.2168.4170.2-65-83.5000112.1E111 G130 K131 V134 T626 F628 A637 V638E111-F128 WeakPolarHBondContact OE1-CZ 3.34Å; F128-G130 PolarHBondContact O-N 3.28Å; F128-K131 PolarHBondContact O-N 3.38Å; F128-V134 HydrophobicContact CD2-CG2 3.71Å; F128-V134 HydrophobicContact CE2-CG2 3.41Å; F128-V134 VanDerWaalsContact CE2-CG2 3.41Å; F128-V134 HydrophobicContact CZ-CG2 4.43Å; F128-T626 HydrophobicContact CE1-CG2 4.01Å; F128-T626 HydrophobicContact CZ-CG2 4.46Å; F128-F628 HydrophobicContact CE2-CE2 4.11Å; F128-F628 HydrophobicContact CZ-CD2 4.25Å; F128-F628 AromaticContact CZ-CE2 3.89Å; F128-F628 HydrophobicContact CZ-CE2 3.89Å; F128-A637 HydrophobicContact CD1-CB 3.99Å; F128-A637 HydrophobicContact CD2-CB 4.1Å; F128-A637 HydrophobicContact CE1-CB 3.98Å; F128-A637 HydrophobicContact CE2-CB 4.11Å; F128-A637 HydrophobicContact CG-CB 4.06Å; F128-A637 HydrophobicContact CZ-CB 4.05Å; F128-V638 HydrophobicContact CD1-CG2 4.04Å; F128-V638 HydrophobicContact CE1-CG2 4.05Å
129K79.9Confident91.2Very high143 Ų14376.9 Ų76.962%0.62240%0.398SS*.G310 helixtrans-54.1130.8177.3-171.6175.9-178.5175.20109.9K131K129-K131 VanDerWaalsContact C-N 3.31Å
130G77.1Confident91.2Very high70 Ų7073.4 Ų73.472%0.72237%0.373SS*.G310 helixtrans78.97-176.400000115.2F128 K132F128-G130 PolarHBondContact O-N 3.28Å; G130-K132 PolarHBondContact O-N 3.47Å; G130-K132 VanDerWaalsContact O-N 3.14Å
131K81.1Confident91.2Very high171 Ų17173.1 Ų73.174%0.74337%0.371SS*.G310 helixtrans54.528.3-179.4-60-179.1177.6-176.90113.5F128 K129F128-K131 PolarHBondContact O-N 3.38Å; K129-K131 VanDerWaalsContact C-N 3.31Å
132K76.4Confident91.1Very high151 Ų15163.3 Ų63.366%0.65733%0.334SS*.PPolyproline II helixtrans-66.3129.7175.6-70-171.9173.7-168.60109.3G130G130-K132 PolarHBondContact O-N 3.47Å; G130-K132 VanDerWaalsContact O-N 3.14Å
133P80.6Confident91Very high109 Ų10963.6 Ų63.671%0.70833%0.33SS*.PPolyproline II helixtrans-66.9150.6171.630-33.5000109.6
134V90.3Very high90.9Very high19 Ų1960.3 Ų60.312%0.11532%0.315CS..BIsolated β-bridgetrans-84.8127.3170.61800000107.6I109 F128 S138 F628 A637I109-V134 HydrophobicContact CG2-CB 3.61Å; I109-V134 HydrophobicContact CG2-CG1 3.34Å; F128-V134 HydrophobicContact CD2-CG2 3.71Å; F128-V134 HydrophobicContact CE2-CG2 3.41Å; F128-V134 VanDerWaalsContact CE2-CG2 3.41Å; F128-V134 HydrophobicContact CZ-CG2 4.43Å; V134-S138 WeakPolarHBondContact CG1-OG 3.39Å; V134-F628 HydrophobicContact CG1-CB 4.08Å; V134-F628 HydrophobicContact CG1-CD1 3.97Å; V134-F628 HydrophobicContact CG1-CD2 3.75Å; V134-F628 HydrophobicContact CG1-CE1 4.39Å; V134-F628 HydrophobicContact CG1-CE2 4.14Å; V134-F628 HydrophobicContact CG1-CG 3.64Å; V134-F628 HydrophobicContact CG1-CZ 4.46Å; V134-F628 HydrophobicContact CG2-CD2 4.07Å; V134-F628 HydrophobicContact CG2-CE2 4.07Å; V134-A637 HydrophobicContact CG2-CB 4.29Å
135Q92.1Very high91Very high85 Ų8554.9 Ų54.940%0.39729%0.289SS..PPolyproline II helixtrans-63.9141178.4-61-63.9-3.200110.3E137 S138Q135-E137 PolarHBondContact O-N 2.94Å; Q135-S138 WeakPolarHBondContact O-CB 3.01Å; Q135-S138 PolarHBondContact O-N 3.29Å; Q135-S138 PolarHBondContact O-OG 3.26Å
136F95.9Very high91.1Very high11 Ų1152.9 Ų52.95%0.04827%0.273CS..G310 helixtrans-66.5-29.8-175.2-175.7-104.9000112.6Q100 P107 N108 S138 R139 L225Q100-F136 HydrophobicContact CB-CE2 4.31Å; P107-F136 HydrophobicContact CB-CB 4.09Å; P107-F136 HydrophobicContact CB-CD1 3.58Å; P107-F136 HydrophobicContact CB-CD2 3.77Å; P107-F136 HydrophobicContact CB-CE1 3.88Å; P107-F136 HydrophobicContact CB-CE2 4.03Å; P107-F136 HydrophobicContact CB-CG 3.51Å; P107-F136 HydrophobicContact CB-CZ 4.08Å; N108-F136 VanDerWaalsContact C-CD2 3.48Å; N108-F136 WeakPolarHBondContact O-CD2 3.49Å; F136-S138 PolarHBondContact O-N 3.5Å; F136-R139 WeakPolarHBondContact O-CB 3.33Å; F136-R139 WeakPolarHBondContact O-CD 3.34Å; F136-R139 WeakPolarHBondContact O-CG 3.25Å; F136-R139 PolarHBondContact O-N 3.11Å; F136-R139 PolarHBondContact O-NH1 2.88Å; F136-L225 HydrophobicContact CE1-CD1 3.98Å; F136-L225 HydrophobicContact CE1-CD2 3.53Å; F136-L225 HydrophobicContact CE1-CG 4.04Å; F136-L225 HydrophobicContact CZ-CD1 4.34Å; F136-L225 HydrophobicContact CZ-CD2 4Å
137E96.4Very high91.3Very high40 Ų4053.8 Ų53.819%0.18728%0.283CS..G310 helixtrans-70-21.2178.9-6476.9-164.200112.5Q135 R139 G194 R196 Q223Q135-E137 PolarHBondContact O-N 2.94Å; E137-R139 PolarHBondContact O-N 3.46Å; E137-G194 WeakPolarHBondContact CG-O 3.33Å; E137-R196 HydrophobicContact CB-CB 4.42Å; E137-R196 HydrophobicContact CG-CB 4.46Å; E137-R196 PolarHBondContact O-NH1 3.38Å; E137-Q223 HydrophobicContact CG-CG 4.12Å
138S97.1Very high91.7Very high4 Ų451.4 Ų51.43%0.02827%0.266CS..G310 helixtrans-73.5-9.2175.675.80000113.7V134 Q135 F136 F628V134-S138 WeakPolarHBondContact CG1-OG 3.39Å; Q135-S138 WeakPolarHBondContact O-CB 3.01Å; Q135-S138 PolarHBondContact O-N 3.29Å; Q135-S138 PolarHBondContact O-OG 3.26Å; F136-S138 PolarHBondContact O-N 3.5Å; S138-F628 WeakPolarHBondContact O-CA 3.33Å
139R97.4Very high92.2Very high5 Ų550.3 Ų50.32%0.01926%0.261CS..SBendtrans-58.8144.2179.375.6-173.8-168.9-77.6-9.1111.2I109 F136 E137 E145 R196 N631I109-R139 HydrophobicContact CD1-CB 3.8Å; F136-R139 WeakPolarHBondContact O-CB 3.33Å; F136-R139 WeakPolarHBondContact O-CD 3.34Å; F136-R139 WeakPolarHBondContact O-CG 3.25Å; F136-R139 PolarHBondContact O-N 3.11Å; F136-R139 PolarHBondContact O-NH1 2.88Å; E137-R139 PolarHBondContact O-N 3.46Å; R139-E145 IonicContact CZ-OE2 3.64Å; R139-E145 IonicContact NE-OE2 2.97Å; R139-E145 IonicContact NH2-OE1 3.43Å; R139-E145 PolarHBondContact NH2-OE1 2.84Å; R139-E145 IonicContact NH2-OE2 3.01Å; R139-E145 PolarHBondContact NH2-OE2 3.13Å; R139-R196 PolarHBondContact O-NH1 2.94Å; R139-N631 PolarHBondContact O-ND2 3.28Å
140P97.9Very high93.1Very high1 Ų147 Ų471%0.00625%0.248CC..PPolyproline II helixtrans-50.5146.5165.7-28.735.5000112L68 G364 F393 I627L68-P140 HydrophobicContact CD2-CG 4.03Å; P140-G364 WeakPolarHBondContact CB-O 3.4Å; P140-G364 WeakPolarHBondContact CG-O 3.26Å; P140-F393 HydrophobicContact CB-CE2 4.36Å; P140-F393 HydrophobicContact CB-CZ 4Å; P140-F393 HydrophobicContact CG-CE2 4.4Å; P140-F393 HydrophobicContact CG-CZ 4.45Å; P140-I627 HydrophobicContact CG-CB 4.27Å; P140-I627 HydrophobicContact CG-CD1 3.94Å; P140-I627 HydrophobicContact CG-CG1 4.12Å
141I97.4Very high94Very high9 Ų947.9 Ų47.95%0.04624%0.236CC..PPolyproline II helixtrans-64.8145.3169-169.6158.3000109.3E145 Y146 I149 W365I141-E145 HydrophobicContact CD1-CG 4.38Å; I141-E145 HydrophobicContact CG1-CB 4.02Å; I141-E145 HydrophobicContact CG1-CG 4.05Å; I141-Y146 HydrophobicContact CB-CE2 4.25Å; I141-Y146 HydrophobicContact CD1-CD1 3.92Å; I141-Y146 HydrophobicContact CD1-CD2 4.35Å; I141-Y146 HydrophobicContact CD1-CE1 3.55Å; I141-Y146 HydrophobicContact CD1-CE2 4.02Å; I141-Y146 HydrophobicContact CD1-CG 4.3Å; I141-Y146 HydrophobicContact CG1-CD1 4.5Å; I141-Y146 HydrophobicContact CG1-CD2 4.06Å; I141-Y146 HydrophobicContact CG1-CE1 4.27Å; I141-Y146 HydrophobicContact CG1-CE2 3.81Å; I141-Y146 HydrophobicContact CG1-CG 4.4Å; I141-Y146 HydrophobicContact CG2-CD2 4.45Å; I141-Y146 HydrophobicContact CG2-CE2 3.48Å; I141-Y146 VanDerWaalsContact CG2-CE2 3.48Å; I141-Y146 WeakPolarHBondContact CG2-OH 3.31Å; I141-I149 HydrophobicContact CD1-CD1 3.82Å; I141-W365 HydrophobicContact CG2-CE3 4.31Å; I141-W365 HydrophobicContact CG2-CH2 4.01Å; I141-W365 HydrophobicContact CG2-CZ3 3.75Å
142T96.6Very high94.8Very high2 Ų241 Ų411%0.01221%0.207CC..  trans-113.8160.2-178.663.40000110.3L68 V144 E145 Y146 D394L68-T142 HydrophobicContact CD1-CG2 4.17Å; T142-V144 PolarHBondContact O-N 3.26Å; T142-E145 WeakPolarHBondContact O-CA 3.14Å; T142-E145 WeakPolarHBondContact O-CB 3.47Å; T142-E145 PolarHBondContact O-N 3.2Å; T142-E145 PolarHBondContact OG1-N 2.82Å; T142-Y146 WeakPolarHBondContact O-CD2 3.4Å; T142-Y146 PolarHBondContact O-N 2.93Å; T142-D394 VanDerWaalsContact CA-OD2 3.26Å; T142-D394 WeakPolarHBondContact CA-OD2 3.25Å; T142-D394 WeakPolarHBondContact CB-OD1 3.31Å; T142-D394 WeakPolarHBondContact CB-OD2 3.21Å
143I95.4Very high95.8Very high68 Ų6834 Ų3435%0.34918%0.177SC..Hα-helixtrans-55.8-40.2177.6-167.864.1000111.8R58 E145 Y146 D147 D394R58-I143 HydrophobicContact CG-CG2 4.32Å; I143-E145 VanDerWaalsContact C-N 3.29Å; I143-E145 PolarHBondContact O-N 3.08Å; I143-Y146 WeakPolarHBondContact O-CB 3.26Å; I143-Y146 PolarHBondContact O-N 2.92Å; I143-Y146 VanDerWaalsContact O-N 3.16Å; I143-D147 VanDerWaalsContact O-CG 3.22Å; I143-D147 PolarHBondContact O-N 3.21Å; I143-D394 PolarHBondContact N-OD2 3.25Å
144V96.7Very high96.6Very high3 Ų331.2 Ų31.22%0.01816%0.156CC..Hα-helixtrans-67.4-33.8177.4179.50000111.6S59 E60 L62 R64 T142 Y146 D147 H148S59-V144 WeakPolarHBondContact O-CG1 3.48Å; E60-V144 VanDerWaalsContact O-CG1 3.27Å; E60-V144 WeakPolarHBondContact O-CG1 3.39Å; L62-V144 HydrophobicContact CD2-CB 4.37Å; L62-V144 HydrophobicContact CD2-CG1 4.03Å; R64-V144 VanDerWaalsContact NH1-CG1 3.33Å; T142-V144 PolarHBondContact O-N 3.26Å; V144-Y146 VanDerWaalsContact C-N 3.33Å; V144-D147 PolarHBondContact O-N 2.87Å; V144-H148 PolarHBondContact O-CD2 3.38Å; V144-H148 PolarHBondContact O-N 2.97Å
145E97.9Very high96.9Very high0 Ų035.7 Ų35.70%017%0.174CC..Hα-helixtrans-68.9-36.7175.3-167.9169.7177.300111.1L62 R139 I141 T142 I143 H148 I149 R196 H222 W230L62-E145 HydrophobicContact CD1-CG 4.33Å; L62-E145 HydrophobicContact CD2-CB 3.94Å; L62-E145 HydrophobicContact CD2-CG 4.44Å; R139-E145 IonicContact CZ-OE2 3.64Å; R139-E145 IonicContact NE-OE2 2.97Å; R139-E145 IonicContact NH2-OE1 3.43Å; R139-E145 PolarHBondContact NH2-OE1 2.84Å; R139-E145 IonicContact NH2-OE2 3.01Å; R139-E145 PolarHBondContact NH2-OE2 3.13Å; I141-E145 HydrophobicContact CD1-CG 4.38Å; I141-E145 HydrophobicContact CG1-CB 4.02Å; I141-E145 HydrophobicContact CG1-CG 4.05Å; T142-E145 WeakPolarHBondContact O-CA 3.14Å; T142-E145 WeakPolarHBondContact O-CB 3.47Å; T142-E145 PolarHBondContact O-N 3.2Å; T142-E145 PolarHBondContact OG1-N 2.82Å; I143-E145 VanDerWaalsContact C-N 3.29Å; I143-E145 PolarHBondContact O-N 3.08Å; E145-H148 PolarHBondContact O-N 3.4Å; E145-I149 WeakPolarHBondContact O-CG1 3.28Å; E145-I149 PolarHBondContact O-N 2.97Å; E145-R196 IonicContact OE1-CZ 3.02Å; E145-R196 IonicContact OE1-NE 3.5Å; E145-R196 PolarHBondContact OE1-NE 3.45Å; E145-R196 IonicContact OE1-NH2 3.07Å; E145-R196 PolarHBondContact OE1-NH2 3.42Å; E145-R196 IonicContact OE2-CZ 2.78Å; E145-R196 IonicContact OE2-NE 3.48Å; E145-R196 IonicContact OE2-NH2 3.21Å; E145-R196 PolarHBondContact OE2-NH2 3.44Å; E145-H222 IonicContact OE1-CE1 3.39Å; E145-H222 IonicContact OE1-ND1 3.33Å; E145-H222 PolarHBondContact OE1-ND1 2.81Å; E145-W230 HydrophobicContact CG-CH2 4.02Å; E145-W230 HydrophobicContact CG-CZ2 4.42Å
146Y97.6Very high97.1Very high42 Ų4232 Ų3217%0.16516%0.156CC..Hα-helixtrans-62.3-43.2168.7-79.3-59.7000113.3I141 T142 I143 V144 H148 I149 E150 F183 D185 W365I141-Y146 HydrophobicContact CB-CE2 4.25Å; I141-Y146 HydrophobicContact CD1-CD1 3.92Å; I141-Y146 HydrophobicContact CD1-CD2 4.35Å; I141-Y146 HydrophobicContact CD1-CE1 3.55Å; I141-Y146 HydrophobicContact CD1-CE2 4.02Å; I141-Y146 HydrophobicContact CD1-CG 4.3Å; I141-Y146 HydrophobicContact CG1-CD1 4.5Å; I141-Y146 HydrophobicContact CG1-CD2 4.06Å; I141-Y146 HydrophobicContact CG1-CE1 4.27Å; I141-Y146 HydrophobicContact CG1-CE2 3.81Å; I141-Y146 HydrophobicContact CG1-CG 4.4Å; I141-Y146 HydrophobicContact CG2-CD2 4.45Å; I141-Y146 HydrophobicContact CG2-CE2 3.48Å; I141-Y146 VanDerWaalsContact CG2-CE2 3.48Å; I141-Y146 WeakPolarHBondContact CG2-OH 3.31Å; T142-Y146 WeakPolarHBondContact O-CD2 3.4Å; T142-Y146 PolarHBondContact O-N 2.93Å; I143-Y146 WeakPolarHBondContact O-CB 3.26Å; I143-Y146 PolarHBondContact O-N 2.92Å; I143-Y146 VanDerWaalsContact O-N 3.16Å; V144-Y146 VanDerWaalsContact C-N 3.33Å; Y146-H148 PolarHBondContact O-N 3.02Å; Y146-I149 HydrophobicContact CD1-CD1 4.44Å; Y146-I149 CarbonylContact O-C 3.5Å; Y146-I149 WeakPolarHBondContact O-CA 3.5Å; Y146-I149 WeakPolarHBondContact O-CB 3.28Å; Y146-I149 PolarHBondContact O-N 2.84Å; Y146-E150 WeakPolarHBondContact O-CB 3.47Å; Y146-E150 PolarHBondContact O-N 2.89Å; Y146-F183 HydrophobicContact CD1-CE2 4.02Å; Y146-F183 AromaticContact CD1-CZ 3.92Å; Y146-F183 HydrophobicContact CD1-CZ 3.92Å; Y146-F183 HydrophobicContact CE1-CE2 4.08Å; Y146-F183 HydrophobicContact CE1-CZ 4.42Å; Y146-D185 HydrophobicContact CE1-CB 4.38Å; Y146-D185 WeakPolarHBondContact CE1-OD1 3.32Å; Y146-D185 VanDerWaalsContact OH-CG 3.23Å; Y146-D185 PolarHBondContact OH-OD1 2.78Å; Y146-D185 PolarHBondContact OH-OD2 2.86Å; Y146-W365 HydrophobicContact CE2-CZ3 4.27Å; Y146-W365 WeakPolarHBondContact OH-CH2 3.19Å; Y146-W365 WeakPolarHBondContact OH-CZ3 3.41Å
147D97.4Very high97.2Very high84 Ų8431.6 Ų31.645%0.44916%0.155SC..Hα-helixtrans-58.1-36.8177.3-63.1-28.2000111.3I143 V144 E150 N151I143-D147 VanDerWaalsContact O-CG 3.22Å; I143-D147 PolarHBondContact O-N 3.21Å; V144-D147 PolarHBondContact O-N 2.87Å; D147-E150 WeakPolarHBondContact O-CB 3.48Å; D147-N151 VanDerWaalsContact O-CG 3.24Å; D147-N151 PolarHBondContact O-N 2.68Å; D147-N151 VanDerWaalsContact O-N 3.08Å; D147-N151 PolarHBondContact O-ND2 3.03Å; D147-N151 VanDerWaalsContact O-ND2 3.16Å
148H98.1Very high97.2Very high38 Ų3832.6 Ų32.618%0.17617%0.171CC..Hα-helixtrans-72.9-35.7174.4-73.7-56.1000113.4E60 V144 E145 Y146 E150 N151 L152 P227 W230E60-H148 PolarHBondContact O-NE2 3.16Å; V144-H148 PolarHBondContact O-CD2 3.38Å; V144-H148 PolarHBondContact O-N 2.97Å; E145-H148 PolarHBondContact O-N 3.4Å; Y146-H148 PolarHBondContact O-N 3.02Å; H148-E150 VanDerWaalsContact C-N 3.34Å; H148-N151 PolarHBondContact O-N 2.79Å; H148-L152 PolarHBondContact O-N 2.92Å; H148-P227 HydrophobicContact CB-CB 3.97Å; H148-P227 HydrophobicContact CB-CG 4.01Å; H148-P227 VanDerWaalsContact CG-CG 3.43Å; H148-W230 HydrophobicContact CB-CE3 4.4Å; H148-W230 HydrophobicContact CB-CH2 3.45Å; H148-W230 VanDerWaalsContact CB-CH2 3.45Å; H148-W230 HydrophobicContact CB-CZ2 4.42Å; H148-W230 HydrophobicContact CB-CZ3 3.43Å; H148-W230 VanDerWaalsContact CB-CZ3 3.43Å
149I97.9Very high97.2Very high1 Ų136.2 Ų36.21%0.00519%0.187CC..Hα-helixtrans-63.4-45.4173.3-72.6173.2000109.5I141 E145 Y146 N151 L152 L153 F183 I200 W230I141-I149 HydrophobicContact CD1-CD1 3.82Å; E145-I149 WeakPolarHBondContact O-CG1 3.28Å; E145-I149 PolarHBondContact O-N 2.97Å; Y146-I149 HydrophobicContact CD1-CD1 4.44Å; Y146-I149 CarbonylContact O-C 3.5Å; Y146-I149 WeakPolarHBondContact O-CA 3.5Å; Y146-I149 WeakPolarHBondContact O-CB 3.28Å; Y146-I149 PolarHBondContact O-N 2.84Å; I149-N151 VanDerWaalsContact C-N 3.3Å; I149-N151 PolarHBondContact O-N 3.3Å; I149-L152 PolarHBondContact O-N 2.77Å; I149-L152 VanDerWaalsContact O-N 3.1Å; I149-L153 HydrophobicContact CG2-CD1 3.82Å; I149-L153 HydrophobicContact CG2-CG 4.16Å; I149-L153 VanDerWaalsContact O-CG 3.31Å; I149-L153 WeakPolarHBondContact O-CG 3.21Å; I149-L153 PolarHBondContact O-N 2.91Å; I149-F183 HydrophobicContact CG2-CE2 4.08Å; I149-F183 HydrophobicContact CG2-CZ 4.07Å; I149-I200 HydrophobicContact CG2-CD1 3.46Å; I149-I200 VanDerWaalsContact CG2-CD1 3.46Å; I149-W230 HydrophobicContact CG1-CH2 4.23Å; I149-W230 HydrophobicContact CG1-CZ3 3.68Å
150E96.9Very high97.1Very high75 Ų7536 Ų3635%0.3519%0.186SC..Hα-helixtrans-54.5-44.9174.5-17380-13000111.1Y146 D147 H148 L153 N154 Y173 F183Y146-E150 WeakPolarHBondContact O-CB 3.47Å; Y146-E150 PolarHBondContact O-N 2.89Å; D147-E150 WeakPolarHBondContact O-CB 3.48Å; H148-E150 VanDerWaalsContact C-N 3.34Å; E150-L153 PolarHBondContact O-N 2.83Å; E150-N154 PolarHBondContact O-N 2.87Å; E150-N154 PolarHBondContact O-ND2 3.21Å; E150-Y173 VanDerWaalsContact CD-OH 3.22Å; E150-Y173 WeakPolarHBondContact OE1-CE1 3.35Å; E150-Y173 VanDerWaalsContact OE1-CZ 3.25Å; E150-Y173 PolarHBondContact OE1-OH 2.99Å; E150-F183 WeakPolarHBondContact OE2-CE1 3.48Å
151N96.7Very high97.1Very high88 Ų8841.3 Ų41.347%0.47121%0.207SC..Hα-helixtrans-63.7-40.7176-71.6-31.4000112.7D147 H148 I149 N154 K155D147-N151 VanDerWaalsContact O-CG 3.24Å; D147-N151 PolarHBondContact O-N 2.68Å; D147-N151 VanDerWaalsContact O-N 3.08Å; D147-N151 PolarHBondContact O-ND2 3.03Å; D147-N151 VanDerWaalsContact O-ND2 3.16Å; H148-N151 PolarHBondContact O-N 2.79Å; I149-N151 VanDerWaalsContact C-N 3.3Å; I149-N151 PolarHBondContact O-N 3.3Å; N151-N154 WeakPolarHBondContact O-CB 3.3Å; N151-N154 PolarHBondContact O-N 2.77Å; N151-K155 PolarHBondContact O-N 3Å
152L97.6Very high97Very high27 Ų2745.4 Ų45.414%0.14123%0.225CC..Hα-helixtrans-67.1-43.2175.9178.861.9000111.5H148 I149 N154 K155 I156 V220 W230H148-L152 PolarHBondContact O-N 2.92Å; I149-L152 PolarHBondContact O-N 2.77Å; I149-L152 VanDerWaalsContact O-N 3.1Å; L152-N154 VanDerWaalsContact C-N 3.28Å; L152-N154 PolarHBondContact O-N 3.01Å; L152-K155 WeakPolarHBondContact O-CB 3.43Å; L152-K155 PolarHBondContact O-N 2.65Å; L152-K155 VanDerWaalsContact O-N 3.08Å; L152-I156 HydrophobicContact CD1-CD1 4.4Å; L152-I156 HydrophobicContact CG-CD1 3.96Å; L152-I156 WeakPolarHBondContact O-CG1 3.41Å; L152-I156 PolarHBondContact O-N 3.14Å; L152-V220 HydrophobicContact CD2-CB 4.42Å; L152-V220 HydrophobicContact CD2-CG1 3.51Å; L152-V220 HydrophobicContact CD2-CG2 3.99Å; L152-W230 HydrophobicContact CD2-CB 4.22Å; L152-W230 HydrophobicContact CD2-CE3 4.38Å
153L97.9Very high97Very high4 Ų445.4 Ų45.42%0.02123%0.225CC..Hα-helixtrans-62.6-35.9176.1-68.6174.1000111.7I149 E150 K155 I156 A157 Y173 F183 I200 L202 V218I149-L153 HydrophobicContact CG2-CD1 3.82Å; I149-L153 HydrophobicContact CG2-CG 4.16Å; I149-L153 VanDerWaalsContact O-CG 3.31Å; I149-L153 WeakPolarHBondContact O-CG 3.21Å; I149-L153 PolarHBondContact O-N 2.91Å; E150-L153 PolarHBondContact O-N 2.83Å; L153-K155 PolarHBondContact O-N 2.87Å; L153-I156 HydrophobicContact CD2-CD1 4.23Å; L153-I156 PolarHBondContact O-N 2.98Å; L153-A157 WeakPolarHBondContact O-CB 3.49Å; L153-A157 PolarHBondContact O-N 3.3Å; L153-Y173 HydrophobicContact CB-CE1 3.92Å; L153-Y173 HydrophobicContact CB-CE2 4.1Å; L153-Y173 HydrophobicContact CD1-CE2 4.28Å; L153-Y173 WeakPolarHBondContact CD1-OH 3.44Å; L153-F183 HydrophobicContact CD1-CB 4.02Å; L153-F183 HydrophobicContact CD1-CD1 3.45Å; L153-F183 VanDerWaalsContact CD1-CD1 3.45Å; L153-F183 HydrophobicContact CD1-CD2 4.12Å; L153-F183 HydrophobicContact CD1-CE1 3.85Å; L153-F183 HydrophobicContact CD1-CE2 4.47Å; L153-F183 HydrophobicContact CD1-CG 3.59Å; L153-F183 HydrophobicContact CD1-CZ 4.35Å; L153-I200 HydrophobicContact CD1-CG2 4.03Å; L153-I200 HydrophobicContact CD2-CD1 4.36Å; L153-I200 HydrophobicContact CD2-CG2 4.12Å; L153-L202 HydrophobicContact CD2-CD2 4.42Å; L153-V218 HydrophobicContact CD2-CG2 3.93Å
154N97Very high97Very high50 Ų5042.4 Ų42.427%0.26721%0.209SC..Hα-helixtrans-59.1-43.5170.8-86.2-65.5000112.2E150 N151 L152 A158 Y173E150-N154 PolarHBondContact O-N 2.87Å; E150-N154 PolarHBondContact O-ND2 3.21Å; N151-N154 WeakPolarHBondContact O-CB 3.3Å; N151-N154 PolarHBondContact O-N 2.77Å; L152-N154 VanDerWaalsContact C-N 3.28Å; L152-N154 PolarHBondContact O-N 3.01Å; N154-A158 WeakPolarHBondContact O-CB 3.25Å; N154-A158 PolarHBondContact O-N 3.17Å; N154-Y173 WeakPolarHBondContact OD1-CD1 3.06Å
155K96.7Very high97Very high112 Ų11246.2 Ų46.249%0.48723%0.226SC..Hα-helixtrans-63.2-47.7175.7-64.7174.2-174.9174.70110.9N151 L152 L153 A157 A158 Q159 E228N151-K155 PolarHBondContact O-N 3Å; L152-K155 WeakPolarHBondContact O-CB 3.43Å; L152-K155 PolarHBondContact O-N 2.65Å; L152-K155 VanDerWaalsContact O-N 3.08Å; L153-K155 PolarHBondContact O-N 2.87Å; K155-A157 PolarHBondContact O-N 3.41Å; K155-A158 PolarHBondContact O-N 3.02Å; K155-Q159 PolarHBondContact O-N 3.27Å; K155-E228 IonicContact NZ-OE1 3.77Å; K155-E228 PolarHBondContact NZ-OE1 2.81Å; K155-E228 IonicContact NZ-OE2 2.78Å; K155-E228 PolarHBondContact NZ-OE2 3.4Å
156I97.5Very high96.8Very high7 Ų749.7 Ų49.74%0.03624%0.242CC..Hα-helixtrans-59.2-47.3177.9-69.2164.3000111.1L152 L153 Q159 A160 F216 V218 V232 V245L152-I156 HydrophobicContact CD1-CD1 4.4Å; L152-I156 HydrophobicContact CG-CD1 3.96Å; L152-I156 WeakPolarHBondContact O-CG1 3.41Å; L152-I156 PolarHBondContact O-N 3.14Å; L153-I156 HydrophobicContact CD2-CD1 4.23Å; L153-I156 PolarHBondContact O-N 2.98Å; I156-Q159 WeakPolarHBondContact O-CB 3.11Å; I156-Q159 PolarHBondContact O-N 2.99Å; I156-A160 PolarHBondContact O-N 3.15Å; I156-F216 HydrophobicContact CG2-CE1 4.22Å; I156-F216 HydrophobicContact CG2-CZ 4.16Å; I156-V218 HydrophobicContact CD1-CG2 4.44Å; I156-V218 HydrophobicContact CG2-CG1 4.46Å; I156-V232 HydrophobicContact CD1-CG2 3.44Å; I156-V232 VanDerWaalsContact CD1-CG2 3.44Å; I156-V232 HydrophobicContact CG1-CG2 3.95Å; I156-V245 HydrophobicContact CG1-CG2 4.35Å; I156-V245 HydrophobicContact CG2-CG1 4.33Å; I156-V245 HydrophobicContact CG2-CG2 3.83Å
157A96.4Very high96.7Very high3 Ų347.8 Ų47.83%0.02523%0.234CC..Hα-helixtrans-73.2-29.4-176.500000112.9L153 K155 Q159 A160 Y161 L164 Y173L153-A157 WeakPolarHBondContact O-CB 3.49Å; L153-A157 PolarHBondContact O-N 3.3Å; K155-A157 PolarHBondContact O-N 3.41Å; A157-Q159 VanDerWaalsContact C-N 3.29Å; A157-A160 CarbonylContact O-C 3.47Å; A157-A160 PolarHBondContact O-N 3.14Å; A157-Y161 WeakPolarHBondContact O-CA 3.27Å; A157-Y161 PolarHBondContact O-N 3.41Å; A157-L164 HydrophobicContact CB-CD1 3.79Å; A157-Y173 HydrophobicContact CB-CD1 4.37Å; A157-Y173 HydrophobicContact CB-CG 3.84Å
158A96.6Very high96.6Very high62 Ų6243.8 Ų43.851%0.51221%0.213SC..Hα-helixtrans-62.8-40.5170.800000111.1N154 K155 Y161N154-A158 WeakPolarHBondContact O-CB 3.25Å; N154-A158 PolarHBondContact O-N 3.17Å; K155-A158 PolarHBondContact O-N 3.02Å; A158-Y161 WeakPolarHBondContact O-CB 3.29Å; A158-Y161 PolarHBondContact O-N 2.76Å
159Q96.8Very high96.2Very high79 Ų7942.9 Ų42.937%0.36921%0.214SC..Hα-helixtrans-69.4-42.3176.2-176.9173.711.600112.7K155 I156 A157 Y161 V245 E246K155-Q159 PolarHBondContact O-N 3.27Å; I156-Q159 WeakPolarHBondContact O-CB 3.11Å; I156-Q159 PolarHBondContact O-N 2.99Å; A157-Q159 VanDerWaalsContact C-N 3.29Å; Q159-Y161 VanDerWaalsContact C-N 3.27Å; Q159-Y161 PolarHBondContact O-N 3.21Å; Q159-V245 HydrophobicContact CB-CG1 4.25Å; Q159-V245 HydrophobicContact CG-CG1 3.98Å; Q159-E246 PolarHBondContact NE2-OE1 3.44Å; Q159-E246 PolarHBondContact OE1-OE1 3.17Å
160A96.8Very high95.9Very high1 Ų143.7 Ų43.71%0.00822%0.223CC..THydrogen-bonded Turntrans-87.215.6177.200000113.8I156 A157 K162 L163 L164 F216 V245 V249I156-A160 PolarHBondContact O-N 3.15Å; A157-A160 CarbonylContact O-C 3.47Å; A157-A160 PolarHBondContact O-N 3.14Å; A160-K162 PolarHBondContact O-N 3.26Å; A160-L163 PolarHBondContact O-N 2.73Å; A160-L164 HydrophobicContact CB-CD1 4.03Å; A160-L164 HydrophobicContact CB-CG 4.1Å; A160-L164 WeakPolarHBondContact O-CG 3.26Å; A160-L164 PolarHBondContact O-N 3Å; A160-F216 HydrophobicContact CB-CE2 4.39Å; A160-F216 HydrophobicContact CB-CZ 4.47Å; A160-V245 HydrophobicContact CB-CG1 4.04Å; A160-V249 HydrophobicContact CB-CG2 4.17Å
161Y96.9Very high95.8Very high113 Ų11340.1 Ų40.144%0.44321%0.206SC..Hα-helixtrans-53.7-51.3-166.9173.5-94.4000112.9A157 A158 Q159 L163 L164 F165A157-Y161 WeakPolarHBondContact O-CA 3.27Å; A157-Y161 PolarHBondContact O-N 3.41Å; A158-Y161 WeakPolarHBondContact O-CB 3.29Å; A158-Y161 PolarHBondContact O-N 2.76Å; Q159-Y161 VanDerWaalsContact C-N 3.27Å; Q159-Y161 PolarHBondContact O-N 3.21Å; Y161-L163 PolarHBondContact O-N 3.21Å; Y161-L164 PolarHBondContact O-N 2.84Å; Y161-F165 HydrophobicContact CE1-CB 4.39Å; Y161-F165 HydrophobicContact CE1-CG 4.47Å; Y161-F165 HydrophobicContact CE2-CD2 4.29Å; Y161-F165 AromaticContact CZ-CD2 3.94Å; Y161-F165 WeakPolarHBondContact O-CB 3.29Å; Y161-F165 PolarHBondContact O-N 2.96Å
162K95.4Very high95.8Very high95 Ų9536.6 Ų36.641%0.41319%0.188SC..Hα-helixtrans-60.5-46.5-177.5-178.9-179.7173.4-170.80111.7A160 F165 E166 E253A160-K162 PolarHBondContact O-N 3.26Å; K162-F165 PolarHBondContact O-N 2.88Å; K162-E166 WeakPolarHBondContact CE-OE1 3.26Å; K162-E166 HydrophobicContact CG-CG 4.49Å; K162-E166 VanDerWaalsContact CG-OE1 3.3Å; K162-E166 WeakPolarHBondContact CG-OE1 3.47Å; K162-E166 VanDerWaalsContact O-CB 3.31Å; K162-E166 WeakPolarHBondContact O-CB 3.3Å; K162-E166 WeakPolarHBondContact O-CG 3.42Å; K162-E166 PolarHBondContact O-N 3.5Å; K162-E253 IonicContact NZ-OE1 3.62Å; K162-E253 PolarHBondContact NZ-OE1 3.11Å
163L96.5Very high95.6Very high2 Ų235.9 Ų35.91%0.0118%0.184CC..Hα-helixtrans-59.3-53.2176.8177.1160.8000110.5A160 Y161 F165 E166 T167 F216 Y237 L248 Y252A160-L163 PolarHBondContact O-N 2.73Å; Y161-L163 PolarHBondContact O-N 3.21Å; L163-F165 VanDerWaalsContact C-N 3.34Å; L163-F165 PolarHBondContact O-N 3.44Å; L163-E166 PolarHBondContact O-N 2.67Å; L163-T167 VanDerWaalsContact O-CB 3.26Å; L163-T167 WeakPolarHBondContact O-CB 3.46Å; L163-T167 PolarHBondContact O-N 2.7Å; L163-T167 PolarHBondContact O-OG1 3.25Å; L163-F216 HydrophobicContact CD2-CD2 4.26Å; L163-Y237 HydrophobicContact CD2-CD2 4.2Å; L163-Y237 HydrophobicContact CD2-CE2 3.78Å; L163-L248 HydrophobicContact CD1-CD1 3.81Å; L163-L248 HydrophobicContact CD1-CD2 3.94Å; L163-L248 HydrophobicContact CD1-CG 3.68Å; L163-Y252 HydrophobicContact CB-CD1 4.06Å; L163-Y252 HydrophobicContact CB-CD2 4.37Å; L163-Y252 HydrophobicContact CB-CE1 4.09Å; L163-Y252 HydrophobicContact CB-CE2 4.37Å; L163-Y252 HydrophobicContact CB-CG 4.21Å; L163-Y252 HydrophobicContact CD1-CD1 4.42Å; L163-Y252 HydrophobicContact CD1-CD2 3.59Å; L163-Y252 HydrophobicContact CD1-CE2 4.15Å; L163-Y252 HydrophobicContact CD1-CG 3.73Å; L163-Y252 HydrophobicContact CG-CD1 4.37Å; L163-Y252 HydrophobicContact CG-CD2 3.78Å; L163-Y252 HydrophobicContact CG-CE1 4.43Å; L163-Y252 HydrophobicContact CG-CE2 3.81Å; L163-Y252 HydrophobicContact CG-CG 4.06Å
164L96.6Very high95.2Very high4 Ų436.9 Ų36.92%0.02119%0.193CC..Hα-helixtrans-62.4-42-177.6-66.6174.5000111.6A157 A160 Y161 T168 L181 L202 I214 F216A157-L164 HydrophobicContact CB-CD1 3.79Å; A160-L164 HydrophobicContact CB-CD1 4.03Å; A160-L164 HydrophobicContact CB-CG 4.1Å; A160-L164 WeakPolarHBondContact O-CG 3.26Å; A160-L164 PolarHBondContact O-N 3Å; Y161-L164 PolarHBondContact O-N 2.84Å; L164-T168 WeakPolarHBondContact O-CB 3.3Å; L164-T168 VanDerWaalsContact O-CG2 3.25Å; L164-T168 WeakPolarHBondContact O-CG2 3.33Å; L164-T168 PolarHBondContact O-N 2.92Å; L164-T168 PolarHBondContact O-OG1 3.15Å; L164-L181 HydrophobicContact CB-CD1 4.26Å; L164-L181 HydrophobicContact CD1-CD1 4.26Å; L164-L181 HydrophobicContact CD2-CD1 4.44Å; L164-L202 HydrophobicContact CD1-CD1 4.41Å; L164-L202 HydrophobicContact CD2-CD1 4.32Å; L164-I214 HydrophobicContact CD2-CD1 3.73Å; L164-F216 HydrophobicContact CD2-CB 4.3Å; L164-F216 HydrophobicContact CD2-CD1 4.5Å; L164-F216 HydrophobicContact CD2-CD2 3.92Å; L164-F216 HydrophobicContact CD2-CE2 4.33Å; L164-F216 HydrophobicContact CD2-CG 4.01Å
165F95.3Very high94.7Very high84 Ų8442.9 Ų42.937%0.36823%0.225SC..Hα-helixtrans-67.2-45.7-179.7-167.4-92.1000112.2Y161 K162 L163 G169 G170Y161-F165 HydrophobicContact CE1-CB 4.39Å; Y161-F165 HydrophobicContact CE1-CG 4.47Å; Y161-F165 HydrophobicContact CE2-CD2 4.29Å; Y161-F165 AromaticContact CZ-CD2 3.94Å; Y161-F165 WeakPolarHBondContact O-CB 3.29Å; Y161-F165 PolarHBondContact O-N 2.96Å; K162-F165 PolarHBondContact O-N 2.88Å; L163-F165 VanDerWaalsContact C-N 3.34Å; L163-F165 PolarHBondContact O-N 3.44Å; F165-G169 PolarHBondContact O-N 3.03Å; F165-G170 VanDerWaalsContact CE2-CA 3.48Å; F165-G170 PolarHBondContact O-N 2.9Å
166E94.9Very high94.4Very high73 Ų7339.5 Ų39.534%0.34122%0.215SC..Hα-helixtrans-62.8-46.5175.3-75.3179-16100110.9K162 L163 T168 Y252 K259K162-E166 WeakPolarHBondContact CE-OE1 3.26Å; K162-E166 HydrophobicContact CG-CG 4.49Å; K162-E166 VanDerWaalsContact CG-OE1 3.3Å; K162-E166 WeakPolarHBondContact CG-OE1 3.47Å; K162-E166 VanDerWaalsContact O-CB 3.31Å; K162-E166 WeakPolarHBondContact O-CB 3.3Å; K162-E166 WeakPolarHBondContact O-CG 3.42Å; K162-E166 PolarHBondContact O-N 3.5Å; L163-E166 PolarHBondContact O-N 2.67Å; E166-T168 PolarHBondContact O-N 3.07Å; E166-Y252 WeakPolarHBondContact CB-OH 3.05Å; E166-Y252 PolarHBondContact OE2-OH 2.75Å; E166-K259 IonicContact OE2-NZ 3.43Å; E166-K259 PolarHBondContact OE2-NZ 2.84Å
167T95.3Very high93.8Very high1 Ų144.4 Ų44.41%0.00625%0.25CS..Hα-helixtrans-65-41.7-176.5-65.10000112.9L163 Y237 L260 L262L163-T167 VanDerWaalsContact O-CB 3.26Å; L163-T167 WeakPolarHBondContact O-CB 3.46Å; L163-T167 PolarHBondContact O-N 2.7Å; L163-T167 PolarHBondContact O-OG1 3.25Å; T167-Y237 HydrophobicContact CG2-CE2 4.24Å; T167-Y237 PolarHBondContact OG1-OH 3.43Å; T167-L260 VanDerWaalsContact CA-O 3.31Å; T167-L260 WeakPolarHBondContact CA-O 3.33Å; T167-L260 HydrophobicContact CG2-CB 3.97Å; T167-L260 PolarHBondContact OG1-O 3Å; T167-L262 HydrophobicContact CG2-CD1 4.41Å; T167-L262 HydrophobicContact CG2-CG 4.25Å; T167-L262 WeakPolarHBondContact O-CB 3.38Å; T167-L262 WeakPolarHBondContact O-CG 3.32Å; T167-L262 PolarHBondContact O-N 2.92Å
168T94.8Very high93.3Very high0 Ų049.7 Ų49.70%028%0.278CS..Hα-helixtrans-89.8-4.7-171.260.30000113.9L164 E166 F171 L181 K204 I214 L262L164-T168 WeakPolarHBondContact O-CB 3.3Å; L164-T168 VanDerWaalsContact O-CG2 3.25Å; L164-T168 WeakPolarHBondContact O-CG2 3.33Å; L164-T168 PolarHBondContact O-N 2.92Å; L164-T168 PolarHBondContact O-OG1 3.15Å; E166-T168 PolarHBondContact O-N 3.07Å; T168-F171 WeakPolarHBondContact OG1-CA 3.36Å; T168-F171 WeakPolarHBondContact OG1-CB 2.92Å; T168-F171 PolarHBondContact OG1-N 3.49Å; T168-F171 PolarHBondContact OG1-O 3.18Å; T168-L181 HydrophobicContact CG2-CD2 4.1Å; T168-K204 WeakPolarHBondContact O-CE 3.26Å; T168-K204 PolarHBondContact O-NZ 2.71Å; T168-K204 VanDerWaalsContact O-NZ 3.13Å; T168-I214 HydrophobicContact CG2-CB 3.96Å; T168-I214 HydrophobicContact CG2-CD1 3.87Å; T168-I214 HydrophobicContact CG2-CG2 3.73Å; T168-L262 HydrophobicContact CG2-CD1 4.44Å
169G89.9Confident93.1Very high20 Ų2049.2 Ų49.221%0.20626%0.263CS..THydrogen-bonded Turntrans70.846.6-174.100000111.4F165 R179F165-G169 PolarHBondContact O-N 3.03Å; G169-R179 PolarHBondContact O-NH2 3.17Å
170G91.9Very high93.1Very high18 Ų1846.5 Ų46.519%0.18625%0.252CS..SBendtrans90.723.1172.200000116.1F165F165-G170 VanDerWaalsContact CE2-CA 3.48Å; F165-G170 PolarHBondContact O-N 2.9Å
171F95Very high93.2Very high0 Ų046.8 Ų46.80%025%0.254CS..  trans-87.8146.1165.1-72.1-116000109.9T168 R179 C180 L181 K204 V206 H265T168-F171 WeakPolarHBondContact OG1-CA 3.36Å; T168-F171 WeakPolarHBondContact OG1-CB 2.92Å; T168-F171 PolarHBondContact OG1-N 3.49Å; T168-F171 PolarHBondContact OG1-O 3.18Å; F171-R179 VanDerWaalsContact CA-O 3.22Å; F171-R179 WeakPolarHBondContact CA-O 3.23Å; F171-R179 HydrophobicContact CB-CB 4.43Å; F171-R179 WeakPolarHBondContact CB-O 3.37Å; F171-R179 HydrophobicContact CD1-CB 3.84Å; F171-R179 WeakPolarHBondContact CD1-O 3.18Å; F171-R179 HydrophobicContact CD2-CB 4.11Å; F171-R179 HydrophobicContact CE1-CB 4.02Å; F171-R179 HydrophobicContact CE2-CB 4.29Å; F171-R179 HydrophobicContact CE2-CG 4.36Å; F171-R179 VanDerWaalsContact CE2-NH2 3.34Å; F171-R179 HydrophobicContact CG-CB 3.86Å; F171-R179 HydrophobicContact CZ-CB 4.23Å; F171-R179 HydrophobicContact CZ-CG 4.3Å; F171-C180 VanDerWaalsContact CD1-O 3.27Å; F171-C180 WeakPolarHBondContact CD1-O 2.85Å; F171-L181 HydrophobicContact CB-CD2 3.6Å; F171-L181 HydrophobicContact CB-CG 4.03Å; F171-L181 HydrophobicContact CD1-CD2 4.3Å; F171-L181 HydrophobicContact CG-CD2 4.28Å; F171-K204 HydrophobicContact CD1-CB 4.08Å; F171-K204 HydrophobicContact CD1-CG 4.13Å; F171-K204 HydrophobicContact CD2-CD 4.19Å; F171-K204 HydrophobicContact CD2-CG 4.37Å; F171-K204 HydrophobicContact CE1-CB 3.83Å; F171-K204 HydrophobicContact CE1-CD 4.42Å; F171-K204 HydrophobicContact CE1-CG 4.17Å; F171-K204 HydrophobicContact CE2-CD 3.9Å; F171-K204 HydrophobicContact CE2-CG 4.37Å; F171-K204 HydrophobicContact CG-CG 4.27Å; F171-K204 HydrophobicContact CZ-CB 4.21Å; F171-K204 HydrophobicContact CZ-CD 4.05Å; F171-K204 HydrophobicContact CZ-CG 4.3Å; F171-V206 HydrophobicContact CE1-CG1 3.79Å; F171-V206 HydrophobicContact CZ-CG1 3.87Å; F171-H265 HydrophobicContact CE2-CB 4.08Å; F171-H265 HydrophobicContact CZ-CB 4.36Å
172S95.1Very high93.2Very high13 Ų1342.5 Ų42.59%0.09124%0.239CC..BIsolated β-bridgetrans-132.4153.8171.566.30000110.1A174 C176 R179 C180 L181S172-A174 WeakPolarHBondContact CB-O 3.44Å; S172-A174 PolarHBondContact OG-O 2.84Å; S172-C176 WeakPolarHBondContact O-CB 3.46Å; S172-C176 WeakPolarHBondContact OG-CB 3.32Å; S172-R179 PolarHBondContact N-O 3.3Å; S172-C180 CarbonylContact O-C 2.94Å; S172-C180 WeakPolarHBondContact O-CA 3.36Å; S172-L181 PolarHBondContact O-N 3.06Å
173Y94.6Very high93.3Very high12 Ų1239 Ų395%0.04722%0.224CC..SBendtrans-81-49.9173.5-160.1-76.8000110.2E150 L153 N154 A157 L181 F183 L202E150-Y173 VanDerWaalsContact CD-OH 3.22Å; E150-Y173 WeakPolarHBondContact OE1-CE1 3.35Å; E150-Y173 VanDerWaalsContact OE1-CZ 3.25Å; E150-Y173 PolarHBondContact OE1-OH 2.99Å; L153-Y173 HydrophobicContact CB-CE1 3.92Å; L153-Y173 HydrophobicContact CB-CE2 4.1Å; L153-Y173 HydrophobicContact CD1-CE2 4.28Å; L153-Y173 WeakPolarHBondContact CD1-OH 3.44Å; N154-Y173 WeakPolarHBondContact OD1-CD1 3.06Å; A157-Y173 HydrophobicContact CB-CD1 4.37Å; A157-Y173 HydrophobicContact CB-CG 3.84Å; Y173-L181 HydrophobicContact CD2-CB 3.7Å; Y173-L181 HydrophobicContact CG-CB 4.31Å; Y173-F183 VanDerWaalsContact OH-CD1 3.26Å; Y173-F183 WeakPolarHBondContact OH-CD1 3.31Å; Y173-L202 HydrophobicContact CD2-CD1 4.49Å; Y173-L202 HydrophobicContact CD2-CD2 4.15Å; Y173-L202 HydrophobicContact CE2-CD2 3.88Å
174A88.7Confident93.4Very high26 Ų2639 Ų3922%0.21522%0.224CC..SBendtrans-90.2150.3176.600000111.8S172 C176S172-A174 WeakPolarHBondContact CB-O 3.44Å; S172-A174 PolarHBondContact OG-O 2.84Å; A174-C176 PolarHBondContact O-N 2.58Å; A174-C176 VanDerWaalsContact O-N 3.08Å
175N86.7Confident93.4Very high175 Ų17539.4 Ų39.494%0.93623%0.227SC*.SBendtrans52.328.4176.8-61.6-29.4000114.6
176C90.5Very high93.5Very high41 Ų4135.5 Ų35.528%0.27721%0.209SC..  trans-83.5156.8175.165.60000110.8S172 A174 C180S172-C176 WeakPolarHBondContact O-CB 3.46Å; S172-C176 WeakPolarHBondContact OG-CB 3.32Å; A174-C176 PolarHBondContact O-N 2.58Å; A174-C176 VanDerWaalsContact O-N 3.08Å; C176-C180 HydrophobicContact CB-CB 3.88Å; C176-C180 WeakPolarHBondContact CB-SG 3.04Å; C176-C180 WeakPolarHBondContact SG-CA 3.39Å; C176-C180 WeakPolarHBondContact SG-CB 3.26Å; C176-C180 CovalentContact SG-SG 2.03Å; C176-C180 PolarHBondContact SG-SG 2.73Å
177S86.1Confident93.7Very high111 Ų11132 Ų3278%0.77619%0.193SC*.SBendtrans-118.6-66172.953.70000111.2
178N86.1Confident93.8Very high114 Ų11432 Ų3261%0.6119%0.193SC*.SBendtrans-111.2-7.2-18062.3-16.8000114
179R92.4Very high93.9Very high51 Ų5132.1 Ų32.119%0.19219%0.194CC..SBendtrans-124.761.8-178.8-61.7-178.777.285.4-13.9110.3G169 F171 S172G169-R179 PolarHBondContact O-NH2 3.17Å; F171-R179 VanDerWaalsContact CA-O 3.22Å; F171-R179 WeakPolarHBondContact CA-O 3.23Å; F171-R179 HydrophobicContact CB-CB 4.43Å; F171-R179 WeakPolarHBondContact CB-O 3.37Å; F171-R179 HydrophobicContact CD1-CB 3.84Å; F171-R179 WeakPolarHBondContact CD1-O 3.18Å; F171-R179 HydrophobicContact CD2-CB 4.11Å; F171-R179 HydrophobicContact CE1-CB 4.02Å; F171-R179 HydrophobicContact CE2-CB 4.29Å; F171-R179 HydrophobicContact CE2-CG 4.36Å; F171-R179 VanDerWaalsContact CE2-NH2 3.34Å; F171-R179 HydrophobicContact CG-CB 3.86Å; F171-R179 HydrophobicContact CZ-CB 4.23Å; F171-R179 HydrophobicContact CZ-CG 4.3Å; S172-R179 PolarHBondContact N-O 3.3Å
180C96.4Very high94.3Very high22 Ų2231.3 Ų31.315%0.14919%0.186CC..BIsolated β-bridgetrans-87.9144.8-177-67.60000111.9F171 S172 C176 F205F171-C180 VanDerWaalsContact CD1-O 3.27Å; F171-C180 WeakPolarHBondContact CD1-O 2.85Å; S172-C180 CarbonylContact O-C 2.94Å; S172-C180 WeakPolarHBondContact O-CA 3.36Å; C176-C180 HydrophobicContact CB-CB 3.88Å; C176-C180 WeakPolarHBondContact CB-SG 3.04Å; C176-C180 WeakPolarHBondContact SG-CA 3.39Å; C176-C180 WeakPolarHBondContact SG-CB 3.26Å; C176-C180 CovalentContact SG-SG 2.03Å; C176-C180 PolarHBondContact SG-SG 2.73Å; C180-F205 HydrophobicContact CB-CB 4.11Å; C180-F205 HydrophobicContact CB-CD1 4.19Å; C180-F205 WeakPolarHBondContact O-CA 3.42Å; C180-F205 WeakPolarHBondContact O-CB 3.03Å; C180-F205 PolarHBondContact O-N 2.78Å
181L97.6Very high94.5Very high8 Ų834.2 Ų34.24%0.04220%0.197CC..EExtended strand (participates in β ladder)trans-85.1153.6162.4-61178.4000109.8L164 T168 F171 S172 Y173 Q203 K204 I214L164-L181 HydrophobicContact CB-CD1 4.26Å; L164-L181 HydrophobicContact CD1-CD1 4.26Å; L164-L181 HydrophobicContact CD2-CD1 4.44Å; T168-L181 HydrophobicContact CG2-CD2 4.1Å; F171-L181 HydrophobicContact CB-CD2 3.6Å; F171-L181 HydrophobicContact CB-CG 4.03Å; F171-L181 HydrophobicContact CD1-CD2 4.3Å; F171-L181 HydrophobicContact CG-CD2 4.28Å; S172-L181 PolarHBondContact O-N 3.06Å; Y173-L181 HydrophobicContact CD2-CB 3.7Å; Y173-L181 HydrophobicContact CG-CB 4.31Å; L181-Q203 CarbonylContact C-O 3.55Å; L181-Q203 VanDerWaalsContact CA-O 3.3Å; L181-Q203 WeakPolarHBondContact CA-O 3.37Å; L181-Q203 WeakPolarHBondContact CD2-O 3.27Å; L181-K204 HydrophobicContact CD2-CG 4.43Å; L181-I214 HydrophobicContact CD1-CD1 3.98Å; L181-I214 HydrophobicContact CD2-CD1 4.21Å; L181-I214 HydrophobicContact CD2-CG2 4.3Å
182T97.7Very high94.6Very high23 Ų2335.9 Ų35.914%0.14121%0.21CC..EExtended strand (participates in β ladder)trans-135.7-176171.4-170.50000108.7L202 Q203 F205 Y209T182-L202 WeakPolarHBondContact O-CA 3.41Å; T182-Q203 HydrophobicContact CG2-CB 4.07Å; T182-Q203 PolarHBondContact N-O 3.22Å; T182-Q203 PolarHBondContact O-N 2.91Å; T182-F205 HydrophobicContact CG2-CB 3.83Å; T182-F205 HydrophobicContact CG2-CD2 3.74Å; T182-F205 HydrophobicContact CG2-CG 4.12Å; T182-Y209 HydrophobicContact CG2-CD2 3.49Å; T182-Y209 VanDerWaalsContact CG2-CD2 3.49Å; T182-Y209 HydrophobicContact CG2-CE2 4Å; T182-Y209 HydrophobicContact CG2-CG 3.92Å
183F98Very high94.6Very high21 Ų2137.8 Ų37.89%0.09222%0.222CC..EExtended strand (participates in β ladder)trans-139.8158.9-179.772-84.3000113.6Y146 I149 E150 L153 Y173 D185 I200 M201 L202 Y448Y146-F183 HydrophobicContact CD1-CE2 4.02Å; Y146-F183 AromaticContact CD1-CZ 3.92Å; Y146-F183 HydrophobicContact CD1-CZ 3.92Å; Y146-F183 HydrophobicContact CE1-CE2 4.08Å; Y146-F183 HydrophobicContact CE1-CZ 4.42Å; I149-F183 HydrophobicContact CG2-CE2 4.08Å; I149-F183 HydrophobicContact CG2-CZ 4.07Å; E150-F183 WeakPolarHBondContact OE2-CE1 3.48Å; L153-F183 HydrophobicContact CD1-CB 4.02Å; L153-F183 HydrophobicContact CD1-CD1 3.45Å; L153-F183 VanDerWaalsContact CD1-CD1 3.45Å; L153-F183 HydrophobicContact CD1-CD2 4.12Å; L153-F183 HydrophobicContact CD1-CE1 3.85Å; L153-F183 HydrophobicContact CD1-CE2 4.47Å; L153-F183 HydrophobicContact CD1-CG 3.59Å; L153-F183 HydrophobicContact CD1-CZ 4.35Å; Y173-F183 VanDerWaalsContact OH-CD1 3.26Å; Y173-F183 WeakPolarHBondContact OH-CD1 3.31Å; F183-D185 HydrophobicContact CD2-CB 4.49Å; F183-D185 HydrophobicContact CE2-CB 4.4Å; F183-I200 HydrophobicContact CB-CG2 3.6Å; F183-I200 HydrophobicContact CD2-CG2 3.7Å; F183-I200 HydrophobicContact CG-CG2 3.92Å; F183-M201 VanDerWaalsContact CA-O 3.23Å; F183-M201 WeakPolarHBondContact CA-O 3.4Å; F183-L202 HydrophobicContact CB-CD2 3.84Å; F183-Y448 PolarHBondContact O-OH 3.07Å
184S97.9Very high94.6Very high2 Ų238.1 Ų38.11%0.01423%0.229CC..EExtended strand (participates in β ladder)trans-117.8139161-56.60000108.7I200 M201 Q203 Y448S184-I200 WeakPolarHBondContact O-CA 3.4Å; S184-M201 PolarHBondContact N-O 3.21Å; S184-M201 PolarHBondContact O-N 3.43Å; S184-Q203 VanDerWaalsContact OG-CD 3.3Å; S184-Q203 PolarHBondContact OG-NE2 2.85Å; S184-Q203 VanDerWaalsContact OG-NE2 3.11Å; S184-Q203 PolarHBondContact OG-OE1 3.06Å; S184-Y448 PolarHBondContact OG-OH 3.15Å
185D97.1Very high95Very high13 Ų1339 Ų397%0.0723%0.229CC..EExtended strand (participates in β ladder)trans-103.9145.5175.877.7-72.6000112.1Y146 F183 R189 T198 I200 Y360Y146-D185 HydrophobicContact CE1-CB 4.38Å; Y146-D185 WeakPolarHBondContact CE1-OD1 3.32Å; Y146-D185 VanDerWaalsContact OH-CG 3.23Å; Y146-D185 PolarHBondContact OH-OD1 2.78Å; Y146-D185 PolarHBondContact OH-OD2 2.86Å; F183-D185 HydrophobicContact CD2-CB 4.49Å; F183-D185 HydrophobicContact CE2-CB 4.4Å; D185-R189 IonicContact OD2-CZ 3.38Å; D185-R189 IonicContact OD2-NH1 2.89Å; D185-R189 PolarHBondContact OD2-NH1 3.03Å; D185-R189 IonicContact OD2-NH2 3.85Å; D185-R189 PolarHBondContact OD2-NH2 3.09Å; D185-T198 HydrophobicContact CB-CG2 3.8Å; D185-I200 HydrophobicContact CB-CG1 4.43Å; D185-Y360 PolarHBondContact O-OH 3Å
186I97.4Very high95.5Very high1 Ų130.6 Ų30.61%0.00518%0.184CC..  trans-108.1144-172.8-52.4-54.2000112.2T198 W199 M201 A354 Q357 T358 Y360I186-T198 WeakPolarHBondContact O-CG2 3.29Å; I186-W199 HydrophobicContact CB-CB 4.17Å; I186-W199 WeakPolarHBondContact CB-O 3.48Å; I186-W199 HydrophobicContact CG1-CB 4.18Å; I186-W199 WeakPolarHBondContact CG1-O 3.23Å; I186-W199 PolarHBondContact N-O 3.1Å; I186-M201 HydrophobicContact CD1-SD 4.4Å; I186-A354 HydrophobicContact CD1-CB 4.1Å; I186-A354 HydrophobicContact CG1-CB 3.66Å; I186-Q357 HydrophobicContact CG2-CB 4.07Å; I186-Q357 HydrophobicContact CG2-CG 4.18Å; I186-T358 HydrophobicContact CG2-CG2 4.35Å; I186-T358 WeakPolarHBondContact CG2-OG1 3.42Å; I186-Y360 WeakPolarHBondContact CD1-OH 3.24Å
187A97.9Very high95.9Very high0 Ų031 Ų310%018%0.18CC..SBendtrans-132154.4174.100000111.6R189 T358 K359 Y360 Q630A187-R189 HydrophobicContact CB-CG 4.37Å; A187-T358 WeakPolarHBondContact O-CA 3.47Å; A187-K359 PolarHBondContact O-N 3.13Å; A187-Y360 HydrophobicContact CB-CD1 4.36Å; A187-Y360 HydrophobicContact CB-CE1 4.34Å; A187-Q630 VanDerWaalsContact CB-CD 3.41Å; A187-Q630 HydrophobicContact CB-CG 3.81Å; A187-Q630 VanDerWaalsContact CB-NE2 3.28Å
188P98.1Very high96.5Very high2 Ų225.8 Ų25.81%0.01314%0.143CC..SBendcis-69.4156.22.629.5-37.6000113.3G190 Q357 E601 Q630 P633 W634P188-G190 PolarHBondContact O-N 2.77Å; P188-Q357 PolarHBondContact O-NE2 3.42Å; P188-E601 HydrophobicContact CG-CG 4.2Å; P188-Q630 WeakPolarHBondContact CA-O 3.4Å; P188-Q630 VanDerWaalsContact CB-O 3.3Å; P188-Q630 WeakPolarHBondContact CB-O 3.39Å; P188-P633 HydrophobicContact CB-CG 3.88Å; P188-P633 HydrophobicContact CG-CG 4.22Å; P188-W634 HydrophobicContact CB-CH2 3.86Å; P188-W634 HydrophobicContact CB-CZ2 4.23Å; P188-W634 HydrophobicContact CG-CH2 4.34Å; P188-W634 HydrophobicContact CG-CZ2 4.23Å
189R98Very high97.1Very high1 Ų121.7 Ų21.70%0.00412%0.119CC..  trans-94.564.6-167.3-52.8-177-173.1-91.2-4.5112.1D185 A187 E195 R196 R197 T198 N631D185-R189 IonicContact OD2-CZ 3.38Å; D185-R189 IonicContact OD2-NH1 2.89Å; D185-R189 PolarHBondContact OD2-NH1 3.03Å; D185-R189 IonicContact OD2-NH2 3.85Å; D185-R189 PolarHBondContact OD2-NH2 3.09Å; A187-R189 HydrophobicContact CB-CG 4.37Å; R189-E195 CarbonylContact O-C 3.57Å; R189-E195 VanDerWaalsContact O-C 3.28Å; R189-E195 VanDerWaalsContact O-O 3.11Å; R189-R196 HydrophobicContact CB-CG 4.48Å; R189-R196 CarbonylContact O-C 3.46Å; R189-R196 VanDerWaalsContact O-CA 3.25Å; R189-R196 WeakPolarHBondContact O-CA 3.27Å; R189-R196 PolarHBondContact O-N 2.94Å; R189-R197 CarbonylContact C-O 3.52Å; R189-R197 WeakPolarHBondContact CA-O 3.19Å; R189-R197 PolarHBondContact O-N 2.96Å; R189-T198 WeakPolarHBondContact CD-OG1 3.42Å; R189-T198 VanDerWaalsContact CG-OG1 3.24Å; R189-T198 WeakPolarHBondContact CG-OG1 3.23Å; R189-T198 PolarHBondContact NH1-OG1 2.95Å; R189-N631 WeakPolarHBondContact CD-OD1 3.42Å; R189-N631 WeakPolarHBondContact CG-OD1 3.16Å; R189-N631 PolarHBondContact NE-OD1 2.81Å
190G96.8Very high97.4Very high4 Ų419.2 Ų19.24%0.04111%0.11CC..SBendtrans140.2-164.7-17900000111.7P188 E195 R197 Q357 W634P188-G190 PolarHBondContact O-N 2.77Å; G190-E195 WeakPolarHBondContact CA-OE2 3.45Å; G190-R197 PolarHBondContact N-O 2.85Å; G190-R197 VanDerWaalsContact N-O 3.14Å; G190-Q357 PolarHBondContact O-NE2 3.24Å; G190-W634 VanDerWaalsContact O-CH2 3.26Å; G190-W634 WeakPolarHBondContact O-CH2 3.3Å; G190-W634 WeakPolarHBondContact O-CZ2 3.14Å
191L96.5Very high97.5Very high79 Ų7918.2 Ų18.241%0.41410%0.103SC..SBendtrans-125.7-2-175.9-58177.7000113E195 W634L191-E195 PolarHBondContact N-OE2 2.78Å; L191-W634 VanDerWaalsContact C-CZ2 3.5Å
192A96.3Very high97.5Very high34 Ų3418 Ų1828%0.28110%0.102SC..SBendtrans-154.9161.4-174.900000111.5E195 W634A192-E195 HydrophobicContact CB-CG 4.35Å; A192-E195 WeakPolarHBondContact O-CB 3.33Å; A192-E195 PolarHBondContact O-N 2.82Å; A192-W634 VanDerWaalsContact O-CE3 3.31Å; A192-W634 VanDerWaalsContact O-CZ3 3.24Å; A192-W634 WeakPolarHBondContact O-CZ3 3.3Å
193P95.9Very high97.5Very high54 Ų5417 Ų1735%0.35110%0.096SC..THydrogen-bonded Turntrans-53.9140.8176.9-20.127.6000112.7E195 W634 E635P193-E195 PolarHBondContact O-N 2.83Å; P193-W634 HydrophobicContact CG-CB 3.67Å; P193-E635 HydrophobicContact CB-CB 4.31Å; P193-E635 HydrophobicContact CB-CG 4.06Å; P193-E635 HydrophobicContact CG-CB 4.33Å; P193-E635 HydrophobicContact CG-CG 3.7Å
194G94.3Very high97.5Very high19 Ų1916.6 Ų16.620%0.1969%0.094CC..THydrogen-bonded Turntrans74.82.6176.700000115.5E137 Q223E137-G194 WeakPolarHBondContact CG-O 3.33Å; G194-Q223 PolarHBondContact O-NE2 2.95Å; G194-Q223 PolarHBondContact O-OE1 3.48Å
195E97.5Very high97.4Very high43 Ų4322 Ų2220%0.20112%0.117CC..  trans-80.7151.7169.5-65.6-173.2-179.700111.4R189 G190 L191 A192 P193 R197R189-E195 CarbonylContact O-C 3.57Å; R189-E195 VanDerWaalsContact O-C 3.28Å; R189-E195 VanDerWaalsContact O-O 3.11Å; G190-E195 WeakPolarHBondContact CA-OE2 3.45Å; L191-E195 PolarHBondContact N-OE2 2.78Å; A192-E195 HydrophobicContact CB-CG 4.35Å; A192-E195 WeakPolarHBondContact O-CB 3.33Å; A192-E195 PolarHBondContact O-N 2.82Å; P193-E195 PolarHBondContact O-N 2.83Å; E195-R197 VanDerWaalsContact CD-NH2 3.31Å; E195-R197 IonicContact OE1-NH2 3.8Å; E195-R197 PolarHBondContact OE1-NH2 2.94Å; E195-R197 IonicContact OE2-CZ 2.84Å; E195-R197 VanDerWaalsContact OE2-CZ 3.26Å; E195-R197 IonicContact OE2-NE 3.8Å; E195-R197 PolarHBondContact OE2-NE 3.07Å; E195-R197 IonicContact OE2-NH2 3.72Å; E195-R197 PolarHBondContact OE2-NH2 2.95Å
196R98.3Very high97.3Very high0 Ų022.2 Ų22.20%012%0.119CC..  trans-142.672.8172.9-162.1177.1-179.986-4.1111.5E137 R139 E145 R189 H222 Q223E137-R196 HydrophobicContact CB-CB 4.42Å; E137-R196 HydrophobicContact CG-CB 4.46Å; E137-R196 PolarHBondContact O-NH1 3.38Å; R139-R196 PolarHBondContact O-NH1 2.94Å; E145-R196 IonicContact OE1-CZ 3.02Å; E145-R196 IonicContact OE1-NE 3.5Å; E145-R196 PolarHBondContact OE1-NE 3.45Å; E145-R196 IonicContact OE1-NH2 3.07Å; E145-R196 PolarHBondContact OE1-NH2 3.42Å; E145-R196 IonicContact OE2-CZ 2.78Å; E145-R196 IonicContact OE2-NE 3.48Å; E145-R196 IonicContact OE2-NH2 3.21Å; E145-R196 PolarHBondContact OE2-NH2 3.44Å; R189-R196 HydrophobicContact CB-CG 4.48Å; R189-R196 CarbonylContact O-C 3.46Å; R189-R196 VanDerWaalsContact O-CA 3.25Å; R189-R196 WeakPolarHBondContact O-CA 3.27Å; R189-R196 PolarHBondContact O-N 2.94Å; R196-H222 VanDerWaalsContact CG-CE1 3.42Å; R196-H222 WeakPolarHBondContact CG-CE1 3.41Å; R196-H222 PolarHBondContact NE-CE1 3.34Å; R196-H222 PolarHBondContact NE-ND1 3.27Å; R196-H222 PolarHBondContact O-N 2.79Å; R196-Q223 HydrophobicContact CB-CB 3.95Å; R196-Q223 HydrophobicContact CB-CG 4.22Å; R196-Q223 PolarHBondContact O-N 3.31Å
197R98.5Very high97.1Very high50 Ų5026.5 Ų26.519%0.18914%0.139CC..EExtended strand (participates in β ladder)trans-125122-175.7-52.2-177-66.1161.5-3.4110R189 G190 E195 L219 V220 N221 E233R189-R197 CarbonylContact C-O 3.52Å; R189-R197 WeakPolarHBondContact CA-O 3.19Å; R189-R197 PolarHBondContact O-N 2.96Å; G190-R197 PolarHBondContact N-O 2.85Å; G190-R197 VanDerWaalsContact N-O 3.14Å; E195-R197 VanDerWaalsContact CD-NH2 3.31Å; E195-R197 IonicContact OE1-NH2 3.8Å; E195-R197 PolarHBondContact OE1-NH2 2.94Å; E195-R197 IonicContact OE2-CZ 2.84Å; E195-R197 VanDerWaalsContact OE2-CZ 3.26Å; E195-R197 IonicContact OE2-NE 3.8Å; E195-R197 PolarHBondContact OE2-NE 3.07Å; E195-R197 IonicContact OE2-NH2 3.72Å; E195-R197 PolarHBondContact OE2-NH2 2.95Å; R197-L219 HydrophobicContact CB-CD1 4.09Å; R197-V220 CarbonylContact C-O 3.59Å; R197-V220 VanDerWaalsContact CA-O 3.28Å; R197-V220 WeakPolarHBondContact CA-O 3.38Å; R197-N221 HydrophobicContact CG-CB 4.09Å; R197-E233 WeakPolarHBondContact CD-OE1 3.37Å; R197-E233 VanDerWaalsContact CD-OE2 3.3Å; R197-E233 WeakPolarHBondContact CD-OE2 3.33Å; R197-E233 IonicContact CZ-OE2 3.73Å; R197-E233 IonicContact NE-OE2 2.71Å; R197-E233 IonicContact NH1-OE2 3.51Å; R197-E233 PolarHBondContact NH1-OE2 3Å
198T98.6Very high97Very high0 Ų027 Ų270%014%0.144CC..EExtended strand (participates in β ladder)trans-120125.7-170.6-710000111D185 I186 R189 I200 V220 H222D185-T198 HydrophobicContact CB-CG2 3.8Å; I186-T198 WeakPolarHBondContact O-CG2 3.29Å; R189-T198 WeakPolarHBondContact CD-OG1 3.42Å; R189-T198 VanDerWaalsContact CG-OG1 3.24Å; R189-T198 WeakPolarHBondContact CG-OG1 3.23Å; R189-T198 PolarHBondContact NH1-OG1 2.95Å; T198-I200 HydrophobicContact CG2-CG1 3.91Å; T198-V220 PolarHBondContact N-O 3.21Å; T198-V220 PolarHBondContact O-N 3.1Å; T198-H222 WeakPolarHBondContact CB-NE2 3.19Å; T198-H222 PolarHBondContact OG1-NE2 2.81Å
199W98.8Very high97Very high28 Ų2828.9 Ų28.911%0.10615%0.151CC..EExtended strand (participates in β ladder)trans-68.4131.2160.2-81.2107.3000109I186 E217 V218 L219 K234 W236 Y241 P353 A354I186-W199 HydrophobicContact CB-CB 4.17Å; I186-W199 WeakPolarHBondContact CB-O 3.48Å; I186-W199 HydrophobicContact CG1-CB 4.18Å; I186-W199 WeakPolarHBondContact CG1-O 3.23Å; I186-W199 PolarHBondContact N-O 3.1Å; W199-E217 HydrophobicContact CE3-CB 3.91Å; W199-E217 HydrophobicContact CZ3-CB 4.03Å; W199-V218 CarbonylContact C-O 3.56Å; W199-V218 WeakPolarHBondContact CA-O 3.39Å; W199-V218 VanDerWaalsContact CE3-C 3.47Å; W199-L219 HydrophobicContact CD2-CB 3.93Å; W199-L219 HydrophobicContact CD2-CD1 4.25Å; W199-L219 HydrophobicContact CE3-CB 4.04Å; W199-L219 HydrophobicContact CG-CD1 4.1Å; W199-L219 HydrophobicContact CH2-CB 4.04Å; W199-L219 HydrophobicContact CZ2-CB 3.91Å; W199-L219 HydrophobicContact CZ2-CD2 4.3Å; W199-L219 HydrophobicContact CZ3-CB 4.1Å; W199-K234 HydrophobicContact CH2-CB 3.8Å; W199-K234 HydrophobicContact CZ2-CB 4.18Å; W199-W236 HydrophobicContact CH2-CB 4.2Å; W199-W236 HydrophobicContact CZ3-CB 4.05Å; W199-Y241 HydrophobicContact CH2-CE1 4.22Å; W199-Y241 HydrophobicContact CZ2-CE1 4.33Å; W199-P353 HydrophobicContact CD2-CB 3.56Å; W199-P353 HydrophobicContact CD2-CG 4.48Å; W199-P353 HydrophobicContact CE3-CB 3.89Å; W199-P353 HydrophobicContact CE3-CG 4.36Å; W199-P353 HydrophobicContact CG-CB 4.19Å; W199-P353 HydrophobicContact CH2-CB 3.68Å; W199-P353 HydrophobicContact CH2-CG 3.71Å; W199-P353 HydrophobicContact CZ2-CB 3.33Å; W199-P353 HydrophobicContact CZ2-CG 3.83Å; W199-P353 HydrophobicContact CZ3-CB 3.94Å; W199-P353 HydrophobicContact CZ3-CG 3.99Å; W199-A354 HydrophobicContact CB-CB 4.47Å
200I98.6Very high97Very high0 Ų030.1 Ų30.10%016%0.156CC..EExtended strand (participates in β ladder)trans-122.8125.4177.3-61.3175.9000106.9I149 L153 F183 S184 D185 T198 E217 V218 V220I149-I200 HydrophobicContact CG2-CD1 3.46Å; I149-I200 VanDerWaalsContact CG2-CD1 3.46Å; L153-I200 HydrophobicContact CD1-CG2 4.03Å; L153-I200 HydrophobicContact CD2-CD1 4.36Å; L153-I200 HydrophobicContact CD2-CG2 4.12Å; F183-I200 HydrophobicContact CB-CG2 3.6Å; F183-I200 HydrophobicContact CD2-CG2 3.7Å; F183-I200 HydrophobicContact CG-CG2 3.92Å; S184-I200 WeakPolarHBondContact O-CA 3.4Å; D185-I200 HydrophobicContact CB-CG1 4.43Å; T198-I200 HydrophobicContact CG2-CG1 3.91Å; I200-E217 CarbonylContact O-C 3.54Å; I200-E217 WeakPolarHBondContact O-CA 3.28Å; I200-V218 HydrophobicContact CB-CG2 4.04Å; I200-V218 PolarHBondContact N-O 3.29Å; I200-V218 PolarHBondContact O-N 3.25Å; I200-V220 HydrophobicContact CD1-CB 4.23Å; I200-V220 HydrophobicContact CD1-CG2 3.9Å
201M97.9Very high97Very high1 Ų129.9 Ų29.91%0.00515%0.154CC..EExtended strand (participates in β ladder)trans-104.7133.4176.657.5178.1-73.500110.1F183 S184 I186 Q203 P213 E217 A354 A476 T477F183-M201 VanDerWaalsContact CA-O 3.23Å; F183-M201 WeakPolarHBondContact CA-O 3.4Å; S184-M201 PolarHBondContact N-O 3.21Å; S184-M201 PolarHBondContact O-N 3.43Å; I186-M201 HydrophobicContact CD1-SD 4.4Å; M201-Q203 HydrophobicContact CE-CG 4.09Å; M201-P213 HydrophobicContact CE-CB 3.92Å; M201-E217 HydrophobicContact CB-CG 3.84Å; M201-A354 HydrophobicContact CB-CB 4.44Å; M201-A354 HydrophobicContact SD-CB 4.46Å; M201-A476 WeakPolarHBondContact CE-O 3.23Å; M201-T477 HydrophobicContact CE-CG2 4.42Å; M201-T477 HydrophobicContact SD-CG2 4.26Å
202L98.1Very high97Very high4 Ų426.8 Ų26.82%0.02114%0.138CC..EExtended strand (participates in β ladder)trans-87.1146.7175.9-63.4-169.9000111.5L153 L164 Y173 T182 F183 I214 F216L153-L202 HydrophobicContact CD2-CD2 4.42Å; L164-L202 HydrophobicContact CD1-CD1 4.41Å; L164-L202 HydrophobicContact CD2-CD1 4.32Å; Y173-L202 HydrophobicContact CD2-CD1 4.49Å; Y173-L202 HydrophobicContact CD2-CD2 4.15Å; Y173-L202 HydrophobicContact CE2-CD2 3.88Å; T182-L202 WeakPolarHBondContact O-CA 3.41Å; F183-L202 HydrophobicContact CB-CD2 3.84Å; L202-I214 HydrophobicContact CB-CD1 3.71Å; L202-I214 HydrophobicContact CB-CG1 3.77Å; L202-I214 HydrophobicContact CD1-CD1 4.37Å; L202-I214 WeakPolarHBondContact O-CG1 3.47Å; L202-I214 PolarHBondContact O-N 3.38Å; L202-I214 VanDerWaalsContact O-N 3.15Å; L202-F216 HydrophobicContact CD1-CD1 3.58Å; L202-F216 HydrophobicContact CD1-CE1 3.98Å; L202-F216 HydrophobicContact CD1-CG 4.37Å; L202-F216 HydrophobicContact CG-CD1 3.9Å; L202-F216 PolarHBondContact N-O 2.87Å
203Q97.9Very high97.1Very high1 Ų125.5 Ų25.51%0.00513%0.126CC..EExtended strand (participates in β ladder)trans-138.8158.7-177.7-72.8153.4-4100110.6L181 T182 S184 M201 F210 H212L181-Q203 CarbonylContact C-O 3.55Å; L181-Q203 VanDerWaalsContact CA-O 3.3Å; L181-Q203 WeakPolarHBondContact CA-O 3.37Å; L181-Q203 WeakPolarHBondContact CD2-O 3.27Å; T182-Q203 HydrophobicContact CG2-CB 4.07Å; T182-Q203 PolarHBondContact N-O 3.22Å; T182-Q203 PolarHBondContact O-N 2.91Å; S184-Q203 VanDerWaalsContact OG-CD 3.3Å; S184-Q203 PolarHBondContact OG-NE2 2.85Å; S184-Q203 VanDerWaalsContact OG-NE2 3.11Å; S184-Q203 PolarHBondContact OG-OE1 3.06Å; M201-Q203 HydrophobicContact CE-CG 4.09Å; Q203-F210 PolarHBondContact NE2-O 2.76Å; Q203-F210 VanDerWaalsContact NE2-O 3.14Å; Q203-H212 CarbonylContact C-O 3.59Å; Q203-H212 VanDerWaalsContact CA-O 3.23Å; Q203-H212 WeakPolarHBondContact CA-O 3.32Å; Q203-H212 WeakPolarHBondContact CB-O 3.42Å
204K96.6Very high97.1Very high13 Ų1323 Ų236%0.05711%0.11CC..EExtended strand (participates in β ladder)trans-73.4126.2166.7-63.4-179.6175.3-1770109.1T168 F171 L181 V206 Y209 H212 I214 P263T168-K204 WeakPolarHBondContact O-CE 3.26Å; T168-K204 PolarHBondContact O-NZ 2.71Å; T168-K204 VanDerWaalsContact O-NZ 3.13Å; F171-K204 HydrophobicContact CD1-CB 4.08Å; F171-K204 HydrophobicContact CD1-CG 4.13Å; F171-K204 HydrophobicContact CD2-CD 4.19Å; F171-K204 HydrophobicContact CD2-CG 4.37Å; F171-K204 HydrophobicContact CE1-CB 3.83Å; F171-K204 HydrophobicContact CE1-CD 4.42Å; F171-K204 HydrophobicContact CE1-CG 4.17Å; F171-K204 HydrophobicContact CE2-CD 3.9Å; F171-K204 HydrophobicContact CE2-CG 4.37Å; F171-K204 HydrophobicContact CG-CG 4.27Å; F171-K204 HydrophobicContact CZ-CB 4.21Å; F171-K204 HydrophobicContact CZ-CD 4.05Å; F171-K204 HydrophobicContact CZ-CG 4.3Å; L181-K204 HydrophobicContact CD2-CG 4.43Å; K204-V206 HydrophobicContact CB-CG1 4.23Å; K204-V206 HydrophobicContact CB-CG2 4.44Å; K204-V206 PolarHBondContact O-N 2.96Å; K204-Y209 WeakPolarHBondContact O-CB 3.46Å; K204-H212 HydrophobicContact CB-CB 4.01Å; K204-H212 PolarHBondContact N-O 3.28Å; K204-I214 HydrophobicContact CG-CG2 3.78Å; K204-P263 PolarHBondContact NZ-O 3.33Å
205F96.1Very high97.2Very high114 Ų11422.2 Ų22.250%0.510%0.102SC..  trans-81.486178.5-168.8-139.4000111C180 T182 Y209C180-F205 HydrophobicContact CB-CB 4.11Å; C180-F205 HydrophobicContact CB-CD1 4.19Å; C180-F205 WeakPolarHBondContact O-CA 3.42Å; C180-F205 WeakPolarHBondContact O-CB 3.03Å; C180-F205 PolarHBondContact O-N 2.78Å; T182-F205 HydrophobicContact CG2-CB 3.83Å; T182-F205 HydrophobicContact CG2-CD2 3.74Å; T182-F205 HydrophobicContact CG2-CG 4.12Å; F205-Y209 HydrophobicContact CD2-CD1 4.11Å; F205-Y209 HydrophobicContact CD2-CG 4.29Å; F205-Y209 HydrophobicContact CE2-CD1 4.18Å; F205-Y209 HydrophobicContact CE2-CE1 4.39Å
206V94.4Very high97.3Very high19 Ų1920.2 Ų20.212%0.1159%0.093CC..SBendtrans-134.7174.5-177.4-58.50000109.3F171 K204 G208 Y209 H212 H265 L270F171-V206 HydrophobicContact CE1-CG1 3.79Å; F171-V206 HydrophobicContact CZ-CG1 3.87Å; K204-V206 HydrophobicContact CB-CG1 4.23Å; K204-V206 HydrophobicContact CB-CG2 4.44Å; K204-V206 PolarHBondContact O-N 2.96Å; V206-G208 PolarHBondContact O-N 2.95Å; V206-Y209 WeakPolarHBondContact O-CB 3.48Å; V206-Y209 PolarHBondContact O-N 2.91Å; V206-H212 HydrophobicContact CG2-CB 4.36Å; V206-H212 VanDerWaalsContact CG2-CD2 3.47Å; V206-H212 WeakPolarHBondContact CG2-CD2 3.47Å; V206-H265 WeakPolarHBondContact CG1-CE1 3.46Å; V206-L270 HydrophobicContact CB-CD1 4.39Å
207E95Very high97.3Very high91 Ų9120.4 Ų20.443%0.4259%0.093SC..THydrogen-bonded Turntrans-56.3124.3175.9-169.2-170.7164.100110.1L270 S272 T273 Y274E207-L270 HydrophobicContact CB-CD1 3.98Å; E207-S272 VanDerWaalsContact O-CB 3.27Å; E207-S272 WeakPolarHBondContact O-CB 3.36Å; E207-S272 PolarHBondContact O-OG 3.4Å; E207-T273 WeakPolarHBondContact OE1-CA 3.27Å; E207-T273 PolarHBondContact OE1-OG1 2.87Å; E207-T273 VanDerWaalsContact OE2-CB 3.26Å; E207-T273 WeakPolarHBondContact OE2-CB 3.29Å; E207-T273 PolarHBondContact OE2-OG1 3.35Å; E207-Y274 PolarHBondContact OE1-N 2.84Å
208G95.7Very high97.3Very high9 Ų918 Ų189%0.0938%0.084CC..THydrogen-bonded Turntrans6736.8-175.100000114.2V206 F210 I211 H212V206-G208 PolarHBondContact O-N 2.95Å; G208-F210 PolarHBondContact O-N 2.78Å; G208-I211 VanDerWaalsContact O-CG1 3.29Å; G208-I211 WeakPolarHBondContact O-CG1 3.34Å; G208-I211 PolarHBondContact O-N 2.9Å; G208-H212 PolarHBondContact O-CD2 3.03Å
209Y96.9Very high97.3Very high43 Ų4318.9 Ų18.917%0.1699%0.089CC..G310 helixtrans-49.7-22.5-177.469-91.1000115.8T182 K204 F205 V206 I211 H212 Y448T182-Y209 HydrophobicContact CG2-CD2 3.49Å; T182-Y209 VanDerWaalsContact CG2-CD2 3.49Å; T182-Y209 HydrophobicContact CG2-CE2 4Å; T182-Y209 HydrophobicContact CG2-CG 3.92Å; K204-Y209 WeakPolarHBondContact O-CB 3.46Å; F205-Y209 HydrophobicContact CD2-CD1 4.11Å; F205-Y209 HydrophobicContact CD2-CG 4.29Å; F205-Y209 HydrophobicContact CE2-CD1 4.18Å; F205-Y209 HydrophobicContact CE2-CE1 4.39Å; V206-Y209 WeakPolarHBondContact O-CB 3.48Å; V206-Y209 PolarHBondContact O-N 2.91Å; Y209-I211 PolarHBondContact O-N 3.01Å; Y209-I211 VanDerWaalsContact O-N 3.07Å; Y209-H212 PolarHBondContact O-N 2.94Å; Y209-Y448 HydrophobicContact CE2-CE2 4.5Å; Y209-Y448 AromaticContact CE2-CZ 3.97Å; Y209-Y448 WeakPolarHBondContact CE2-OH 3.48Å; Y209-Y448 WeakPolarHBondContact OH-CE2 3.32Å; Y209-Y448 PolarHBondContact OH-OH 3.09Å
210F97.6Very high97.3Very high26 Ų2617.5 Ų17.511%0.1148%0.084CC..G310 helixtrans-51.1-32.8178-50.1-72.6000113.5Q203 G208 Y448 N449 Y473Q203-F210 PolarHBondContact NE2-O 2.76Å; Q203-F210 VanDerWaalsContact NE2-O 3.14Å; G208-F210 PolarHBondContact O-N 2.78Å; F210-Y448 HydrophobicContact CD1-CD1 4.05Å; F210-Y448 AromaticContact CD1-CE1 3.55Å; F210-Y448 HydrophobicContact CD1-CE1 3.55Å; F210-Y448 HydrophobicContact CD1-CE2 4.46Å; F210-Y448 AromaticContact CD1-CZ 3.81Å; F210-Y448 AromaticContact CE1-CD1 3.83Å; F210-Y448 HydrophobicContact CE1-CD1 3.83Å; F210-Y448 AromaticContact CE1-CD2 3.96Å; F210-Y448 HydrophobicContact CE1-CD2 3.96Å; F210-Y448 AromaticContact CE1-CE1 3.56Å; F210-Y448 HydrophobicContact CE1-CE1 3.56Å; F210-Y448 AromaticContact CE1-CE2 3.71Å; F210-Y448 HydrophobicContact CE1-CE2 3.71Å; F210-Y448 HydrophobicContact CE1-CG 4.03Å; F210-Y448 AromaticContact CE1-CZ 3.52Å; F210-N449 HydrophobicContact CB-CB 4.34Å; F210-N449 HydrophobicContact CD1-CB 3.63Å; F210-N449 HydrophobicContact CD2-CB 4.38Å; F210-N449 HydrophobicContact CE1-CB 3.91Å; F210-N449 HydrophobicContact CG-CB 3.87Å; F210-N449 HydrophobicContact CZ-CB 4.4Å; F210-Y473 HydrophobicContact CB-CG 4.45Å; F210-Y473 HydrophobicContact CD2-CD1 4.23Å; F210-Y473 AromaticContact CD2-CD2 3.53Å; F210-Y473 HydrophobicContact CD2-CD2 3.53Å; F210-Y473 HydrophobicContact CD2-CE2 4.25Å; F210-Y473 AromaticContact CD2-CG 3.52Å; F210-Y473 HydrophobicContact CD2-CG 3.52Å; F210-Y473 AromaticContact CE2-CD2 3.72Å; F210-Y473 HydrophobicContact CE2-CD2 3.72Å; F210-Y473 HydrophobicContact CE2-CE2 4.3Å; F210-Y473 HydrophobicContact CE2-CG 4.2Å; F210-Y473 HydrophobicContact CG-CG 4.37Å
211I97.3Very high97.3Very high0 Ų019.1 Ų19.10%09%0.092CC..G310 helixtrans-101.614.5-179.455.5177.5000113.3G208 Y209 P213 Y271 Y473 I474 A476 V494 I672G208-I211 VanDerWaalsContact O-CG1 3.29Å; G208-I211 WeakPolarHBondContact O-CG1 3.34Å; G208-I211 PolarHBondContact O-N 2.9Å; Y209-I211 PolarHBondContact O-N 3.01Å; Y209-I211 VanDerWaalsContact O-N 3.07Å; I211-P213 WeakPolarHBondContact O-CD 3.32Å; I211-Y271 HydrophobicContact CB-CE2 4.37Å; I211-Y271 HydrophobicContact CD1-CD2 4Å; I211-Y271 HydrophobicContact CD1-CE2 3.66Å; I211-Y271 HydrophobicContact CG1-CE2 3.91Å; I211-Y271 PolarHBondContact O-OH 2.98Å; I211-Y473 HydrophobicContact CD1-CD1 4.03Å; I211-Y473 HydrophobicContact CD1-CE1 4.15Å; I211-Y473 HydrophobicContact CG1-CD1 4.25Å; I211-I474 HydrophobicContact CG2-CD1 4.47Å; I211-I474 HydrophobicContact CG2-CG1 3.78Å; I211-A476 HydrophobicContact CB-CB 4.49Å; I211-A476 HydrophobicContact CG2-CB 3.93Å; I211-V494 HydrophobicContact CB-CG1 4.2Å; I211-V494 WeakPolarHBondContact O-CG2 3.48Å; I211-I672 HydrophobicContact CD1-CD1 3.91Å
212H97.2Very high97.3Very high14 Ų1419.1 Ų19.17%0.0659%0.092CC..  trans-113.255.6175.3-65.3-96.7000113.9Q203 K204 V206 G208 Y209 Y271 S272Q203-H212 CarbonylContact C-O 3.59Å; Q203-H212 VanDerWaalsContact CA-O 3.23Å; Q203-H212 WeakPolarHBondContact CA-O 3.32Å; Q203-H212 WeakPolarHBondContact CB-O 3.42Å; K204-H212 HydrophobicContact CB-CB 4.01Å; K204-H212 PolarHBondContact N-O 3.28Å; V206-H212 HydrophobicContact CG2-CB 4.36Å; V206-H212 VanDerWaalsContact CG2-CD2 3.47Å; V206-H212 WeakPolarHBondContact CG2-CD2 3.47Å; G208-H212 PolarHBondContact O-CD2 3.03Å; Y209-H212 PolarHBondContact O-N 2.94Å; H212-Y271 AromaticContact CE1-CE1 3.26Å; H212-Y271 WeakPolarHBondContact CE1-CE1 3.32Å; H212-Y271 AromaticContact CE1-CZ 3.45Å; H212-Y271 VanDerWaalsContact CE1-CZ 3.45Å; H212-Y271 PolarHBondContact CE1-OH 2.96Å; H212-Y271 VanDerWaalsContact CE1-OH 3.3Å; H212-Y271 AromaticContact ND1-CE1 3.79Å; H212-Y271 AromaticContact ND1-CZ 3.79Å; H212-Y271 PolarHBondContact ND1-OH 3.19Å; H212-Y271 AromaticContact NE2-CE1 3.95Å; H212-Y271 AromaticContact NE2-CZ 3.79Å; H212-S272 WeakPolarHBondContact NE2-CB 3.39Å; H212-S272 PolarHBondContact NE2-OG 2.8Å
213P97.6Very high97.3Very high7 Ų722.5 Ų22.55%0.04511%0.108CC..EExtended strand (participates in β ladder)trans-66.2143.9177.131.1-35.7000111.2M201 I211 T477 F478M201-P213 HydrophobicContact CE-CB 3.92Å; I211-P213 WeakPolarHBondContact O-CD 3.32Å; P213-T477 VanDerWaalsContact CG-C 3.42Å; P213-T477 WeakPolarHBondContact CG-O 3.43Å; P213-F478 HydrophobicContact CB-CB 4.22Å; P213-F478 HydrophobicContact CG-CB 4.43Å
214I97.1Very high97.2Very high2 Ų225.3 Ų25.31%0.0112%0.123CC..EExtended strand (participates in β ladder)trans-103.92.5-17867.9161.1000114.5L164 T168 L181 L202 K204 F216 L262L164-I214 HydrophobicContact CD2-CD1 3.73Å; T168-I214 HydrophobicContact CG2-CB 3.96Å; T168-I214 HydrophobicContact CG2-CD1 3.87Å; T168-I214 HydrophobicContact CG2-CG2 3.73Å; L181-I214 HydrophobicContact CD1-CD1 3.98Å; L181-I214 HydrophobicContact CD2-CD1 4.21Å; L181-I214 HydrophobicContact CD2-CG2 4.3Å; L202-I214 HydrophobicContact CB-CD1 3.71Å; L202-I214 HydrophobicContact CB-CG1 3.77Å; L202-I214 HydrophobicContact CD1-CD1 4.37Å; L202-I214 WeakPolarHBondContact O-CG1 3.47Å; L202-I214 PolarHBondContact O-N 3.38Å; L202-I214 VanDerWaalsContact O-N 3.15Å; K204-I214 HydrophobicContact CG-CG2 3.78Å; I214-F216 HydrophobicContact CD1-CB 4.08Å; I214-F216 HydrophobicContact CG1-CB 4.05Å; I214-L262 HydrophobicContact CB-CD1 3.98Å; I214-L262 HydrophobicContact CG2-CD1 4.01Å
215G96.7Very high97.2Very high2 Ų225.4 Ų25.42%0.02112%0.124CC..EExtended strand (participates in β ladder)trans75.724-179.500000114.3Y237 N238 F478G215-Y237 VanDerWaalsContact O-CA 3.26Å; G215-Y237 WeakPolarHBondContact O-CA 3.34Å; G215-Y237 VanDerWaalsContact O-CD2 3.28Å; G215-Y237 WeakPolarHBondContact O-CD2 3.35Å; G215-N238 PolarHBondContact O-N 3.43Å; G215-N238 VanDerWaalsContact O-N 3.11Å; G215-F478 VanDerWaalsContact CA-CB 3.46Å
216F98.1Very high97.3Very high1 Ų122.4 Ų22.40%0.00411%0.113CC..EExtended strand (participates in β ladder)trans-125.1120.5175.9-173.2-81.1000109.5I156 A160 L163 L164 L202 I214 V218 V235 W236 Y237 L248I156-F216 HydrophobicContact CG2-CE1 4.22Å; I156-F216 HydrophobicContact CG2-CZ 4.16Å; A160-F216 HydrophobicContact CB-CE2 4.39Å; A160-F216 HydrophobicContact CB-CZ 4.47Å; L163-F216 HydrophobicContact CD2-CD2 4.26Å; L164-F216 HydrophobicContact CD2-CB 4.3Å; L164-F216 HydrophobicContact CD2-CD1 4.5Å; L164-F216 HydrophobicContact CD2-CD2 3.92Å; L164-F216 HydrophobicContact CD2-CE2 4.33Å; L164-F216 HydrophobicContact CD2-CG 4.01Å; L202-F216 HydrophobicContact CD1-CD1 3.58Å; L202-F216 HydrophobicContact CD1-CE1 3.98Å; L202-F216 HydrophobicContact CD1-CG 4.37Å; L202-F216 HydrophobicContact CG-CD1 3.9Å; L202-F216 PolarHBondContact N-O 2.87Å; I214-F216 HydrophobicContact CD1-CB 4.08Å; I214-F216 HydrophobicContact CG1-CB 4.05Å; F216-V218 HydrophobicContact CD1-CG1 4.18Å; F216-V218 HydrophobicContact CE1-CG1 3.38Å; F216-V218 HydrophobicContact CZ-CG1 3.92Å; F216-V235 HydrophobicContact CE2-CG1 4.02Å; F216-V235 HydrophobicContact CZ-CG1 3.98Å; F216-W236 WeakPolarHBondContact CA-O 3.34Å; F216-Y237 HydrophobicContact CB-CD2 4.21Å; F216-Y237 AromaticContact CD2-CD2 3.97Å; F216-Y237 HydrophobicContact CD2-CD2 3.97Å; F216-L248 HydrophobicContact CD2-CD2 4.05Å; F216-L248 HydrophobicContact CE2-CD2 3.51Å; F216-L248 HydrophobicContact CZ-CD2 4.48Å
217E98.7Very high97.4Very high3 Ų322.7 Ų22.71%0.01412%0.116CC..EExtended strand (participates in β ladder)trans-131.5144.4178.7-51.1-178.8177.800110.2W199 I200 M201 W236 T352 P353 A354W199-E217 HydrophobicContact CE3-CB 3.91Å; W199-E217 HydrophobicContact CZ3-CB 4.03Å; I200-E217 CarbonylContact O-C 3.54Å; I200-E217 WeakPolarHBondContact O-CA 3.28Å; M201-E217 HydrophobicContact CB-CG 3.84Å; E217-W236 HydrophobicContact CB-CB 4.31Å; E217-W236 HydrophobicContact CB-CE3 4.35Å; E217-W236 HydrophobicContact CG-CE3 3.89Å; E217-W236 HydrophobicContact CG-CZ3 4.39Å; E217-W236 PolarHBondContact N-O 3.29Å; E217-W236 PolarHBondContact O-N 2.95Å; E217-T352 WeakPolarHBondContact OE1-CB 3.3Å; E217-T352 PolarHBondContact OE1-OG1 2.78Å; E217-P353 VanDerWaalsContact OE2-CD 3.26Å; E217-P353 WeakPolarHBondContact OE2-CD 3.42Å; E217-A354 VanDerWaalsContact CD-CB 3.43Å; E217-A354 HydrophobicContact CG-CB 4.5Å; E217-A354 WeakPolarHBondContact OE1-CB 3.32Å; E217-A354 WeakPolarHBondContact OE2-CB 3.42Å; E217-A354 PolarHBondContact OE2-N 2.75Å
218V98.7Very high97.5Very high0 Ų025.2 Ų25.20%013%0.127CC..EExtended strand (participates in β ladder)trans-131.1138.2179-670000111L153 I156 W199 I200 F216 V220 V232 V235L153-V218 HydrophobicContact CD2-CG2 3.93Å; I156-V218 HydrophobicContact CD1-CG2 4.44Å; I156-V218 HydrophobicContact CG2-CG1 4.46Å; W199-V218 CarbonylContact C-O 3.56Å; W199-V218 WeakPolarHBondContact CA-O 3.39Å; W199-V218 VanDerWaalsContact CE3-C 3.47Å; I200-V218 HydrophobicContact CB-CG2 4.04Å; I200-V218 PolarHBondContact N-O 3.29Å; I200-V218 PolarHBondContact O-N 3.25Å; F216-V218 HydrophobicContact CD1-CG1 4.18Å; F216-V218 HydrophobicContact CE1-CG1 3.38Å; F216-V218 HydrophobicContact CZ-CG1 3.92Å; V218-V220 HydrophobicContact CG2-CG2 4.17Å; V218-V232 HydrophobicContact CB-CG1 4.45Å; V218-V235 HydrophobicContact CG1-CB 4.48Å; V218-V235 HydrophobicContact CG1-CG1 4.08Å; V218-V235 HydrophobicContact CG1-CG2 4.13Å
219L98.8Very high97.6Very high18 Ų1830.4 Ų30.49%0.09415%0.147CC..EExtended strand (participates in β ladder)trans-93.8111.1172.6-179.859.2000109R197 W199 V232 E233 K234R197-L219 HydrophobicContact CB-CD1 4.09Å; W199-L219 HydrophobicContact CD2-CB 3.93Å; W199-L219 HydrophobicContact CD2-CD1 4.25Å; W199-L219 HydrophobicContact CE3-CB 4.04Å; W199-L219 HydrophobicContact CG-CD1 4.1Å; W199-L219 HydrophobicContact CH2-CB 4.04Å; W199-L219 HydrophobicContact CZ2-CB 3.91Å; W199-L219 HydrophobicContact CZ2-CD2 4.3Å; W199-L219 HydrophobicContact CZ3-CB 4.1Å; L219-V232 CarbonylContact O-C 3.33Å; L219-V232 WeakPolarHBondContact O-CA 3.39Å; L219-E233 HydrophobicContact CD2-CB 4.08Å; L219-E233 HydrophobicContact CG-CB 4.22Å; L219-E233 PolarHBondContact O-N 2.71Å; L219-K234 HydrophobicContact CB-CB 4.03Å; L219-K234 HydrophobicContact CD2-CB 4.44Å; L219-K234 PolarHBondContact N-O 3.45Å
220V98.7Very high97.6Very high0 Ų029.1 Ų29.10%014%0.142CC..EExtended strand (participates in β ladder)trans-103.9126.7179.4174.20000110.1L152 R197 T198 I200 V218 H222 T231L152-V220 HydrophobicContact CD2-CB 4.42Å; L152-V220 HydrophobicContact CD2-CG1 3.51Å; L152-V220 HydrophobicContact CD2-CG2 3.99Å; R197-V220 CarbonylContact C-O 3.59Å; R197-V220 VanDerWaalsContact CA-O 3.28Å; R197-V220 WeakPolarHBondContact CA-O 3.38Å; T198-V220 PolarHBondContact N-O 3.21Å; T198-V220 PolarHBondContact O-N 3.1Å; I200-V220 HydrophobicContact CD1-CB 4.23Å; I200-V220 HydrophobicContact CD1-CG2 3.9Å; V218-V220 HydrophobicContact CG2-CG2 4.17Å; V220-H222 HydrophobicContact CG1-CB 4.3Å; V220-T231 WeakPolarHBondContact CA-O 3.5Å
221N98.6Very high97.7Very high34 Ų3431.1 Ų31.118%0.18216%0.157CC..EExtended strand (participates in β ladder)trans-89.9110166.6-172.3-22.4000109.6R197 Q223 W230 T231 E233R197-N221 HydrophobicContact CG-CB 4.09Å; N221-Q223 VanDerWaalsContact OD1-CB 3.29Å; N221-Q223 WeakPolarHBondContact OD1-CB 3.36Å; N221-Q223 PolarHBondContact OD1-N 3.12Å; N221-Q223 VanDerWaalsContact OD1-N 3.16Å; N221-W230 VanDerWaalsContact O-CA 3.32Å; N221-W230 WeakPolarHBondContact O-CA 3.45Å; N221-W230 WeakPolarHBondContact O-CB 3.2Å; N221-T231 PolarHBondContact N-O 2.95Å; N221-T231 PolarHBondContact O-N 2.95Å; N221-E233 HydrophobicContact CB-CG 4.1Å; N221-E233 WeakPolarHBondContact CB-OE1 3.38Å; N221-E233 PolarHBondContact ND2-OE1 2.76Å
222H98.3Very high97.7Very high0 Ų033 Ų330%017%0.168CC..  trans-117.930.4-178.760.197.4000111.9E145 R196 T198 V220 W230E145-H222 IonicContact OE1-CE1 3.39Å; E145-H222 IonicContact OE1-ND1 3.33Å; E145-H222 PolarHBondContact OE1-ND1 2.81Å; R196-H222 VanDerWaalsContact CG-CE1 3.42Å; R196-H222 WeakPolarHBondContact CG-CE1 3.41Å; R196-H222 PolarHBondContact NE-CE1 3.34Å; R196-H222 PolarHBondContact NE-ND1 3.27Å; R196-H222 PolarHBondContact O-N 2.79Å; T198-H222 WeakPolarHBondContact CB-NE2 3.19Å; T198-H222 PolarHBondContact OG1-NE2 2.81Å; V220-H222 HydrophobicContact CG1-CB 4.3Å; H222-W230 HydrophobicContact CB-CD2 3.63Å; H222-W230 HydrophobicContact CB-CE3 3.94Å; H222-W230 HydrophobicContact CB-CG 4.13Å; H222-W230 HydrophobicContact CB-CH2 4Å; H222-W230 HydrophobicContact CB-CZ2 3.71Å; H222-W230 HydrophobicContact CB-CZ3 4.1Å
223Q97.3Very high97.7Very high75 Ų7535.1 Ų35.135%0.3518%0.178SC..  trans-71.5-39.5-178-173.8174.1-26.100113.5E137 G194 R196 N221E137-Q223 HydrophobicContact CG-CG 4.12Å; G194-Q223 PolarHBondContact O-NE2 2.95Å; G194-Q223 PolarHBondContact O-OE1 3.48Å; R196-Q223 HydrophobicContact CB-CB 3.95Å; R196-Q223 HydrophobicContact CB-CG 4.22Å; R196-Q223 PolarHBondContact O-N 3.31Å; N221-Q223 VanDerWaalsContact OD1-CB 3.29Å; N221-Q223 WeakPolarHBondContact OD1-CB 3.36Å; N221-Q223 PolarHBondContact OD1-N 3.12Å; N221-Q223 VanDerWaalsContact OD1-N 3.16Å
224D97Very high97.8Very high60 Ų6038.2 Ų38.232%0.32119%0.191SC..SBendtrans-67.6140.8178-161.5-54.6000109.9D226 K229 W230D224-D226 PolarHBondContact O-N 3.36Å; D224-D226 VanDerWaalsContact OD1-CB 3.29Å; D224-D226 WeakPolarHBondContact OD1-CB 3.29Å; D224-D226 PolarHBondContact OD1-N 2.86Å; D224-K229 HydrophobicContact CB-CB 4.24Å; D224-K229 HydrophobicContact CB-CD 4.34Å; D224-K229 IonicContact OD1-NZ 3.46Å; D224-K229 WeakPolarHBondContact OD2-CD 3.46Å; D224-K229 IonicContact OD2-NZ 3.99Å; D224-K229 PolarHBondContact OD2-NZ 3.15Å; D224-W230 PolarHBondContact O-NE1 3.05Å
225L96.1Very high97.9Very high15 Ų1538.1 Ų38.18%0.07919%0.19CC..SBendtrans-72.5-5.7176-76178.8000113.3L62 K63 G102 P107 F136 P227L62-L225 HydrophobicContact CB-CD2 3.8Å; K63-L225 HydrophobicContact CD-CB 4.48Å; K63-L225 HydrophobicContact CG-CB 3.61Å; K63-L225 HydrophobicContact CG-CD1 4.24Å; G102-L225 WeakPolarHBondContact O-CD1 3.28Å; P107-L225 HydrophobicContact CB-CD1 4.11Å; P107-L225 HydrophobicContact CG-CD1 3.56Å; F136-L225 HydrophobicContact CE1-CD1 3.98Å; F136-L225 HydrophobicContact CE1-CD2 3.53Å; F136-L225 HydrophobicContact CE1-CG 4.04Å; F136-L225 HydrophobicContact CZ-CD1 4.34Å; F136-L225 HydrophobicContact CZ-CD2 4Å; L225-P227 WeakPolarHBondContact O-CD 3.37Å
226D96.7Very high98Very high52 Ų5238.2 Ų38.228%0.27819%0.19SC..SBendtrans-100.2104.4171.7-166.4-11.3000110.3K63 D224 E228 K229K63-D226 IonicContact NZ-OD2 2.71Å; D224-D226 PolarHBondContact O-N 3.36Å; D224-D226 VanDerWaalsContact OD1-CB 3.29Å; D224-D226 WeakPolarHBondContact OD1-CB 3.29Å; D224-D226 PolarHBondContact OD1-N 2.86Å; D226-E228 PolarHBondContact O-N 3.46Å; D226-E228 VanDerWaalsContact O-N 3.1Å; D226-E228 PolarHBondContact OD1-N 3.06Å; D226-K229 HydrophobicContact CB-CD 4.12Å; D226-K229 HydrophobicContact CB-CG 4.26Å; D226-K229 PolarHBondContact O-N 3.31Å
227P97.1Very high97.9Very high25 Ų2538.2 Ų38.216%0.16219%0.19CC..G310 helixtrans-57.1-25.3-178.1-2736000115L62 H148 L225 K229 W230L62-P227 HydrophobicContact CD1-CG 4.07Å; L62-P227 HydrophobicContact CG-CG 4.49Å; H148-P227 HydrophobicContact CB-CB 3.97Å; H148-P227 HydrophobicContact CB-CG 4.01Å; H148-P227 VanDerWaalsContact CG-CG 3.43Å; L225-P227 WeakPolarHBondContact O-CD 3.37Å; P227-K229 PolarHBondContact O-N 2.91Å; P227-W230 HydrophobicContact CB-CD2 4.13Å; P227-W230 HydrophobicContact CB-CE3 4.32Å; P227-W230 HydrophobicContact CB-CH2 4.47Å; P227-W230 HydrophobicContact CB-CZ2 4.28Å; P227-W230 HydrophobicContact CB-CZ3 4.48Å; P227-W230 HydrophobicContact CG-CZ2 4.19Å; P227-W230 WeakPolarHBondContact O-CB 3.35Å; P227-W230 PolarHBondContact O-N 3.16Å; P227-W230 VanDerWaalsContact O-N 3.16Å
228E96.8Very high97.7Very high143 Ų14339.2 Ų39.267%0.66820%0.195SC*.G310 helixtrans-70.9-10.9178-67.7-60.1132.600113.3K155 D226K155-E228 IonicContact NZ-OE1 3.77Å; K155-E228 PolarHBondContact NZ-OE1 2.81Å; K155-E228 IonicContact NZ-OE2 2.78Å; K155-E228 PolarHBondContact NZ-OE2 3.4Å; D226-E228 PolarHBondContact O-N 3.46Å; D226-E228 VanDerWaalsContact O-N 3.1Å; D226-E228 PolarHBondContact OD1-N 3.06Å
229K97.8Very high97.5Very high118 Ų11841.8 Ų41.851%0.51321%0.213SC..G310 helixtrans-99.10.5174.1-62.1179.2-174.1176.30113.6D224 D226 P227D224-K229 HydrophobicContact CB-CB 4.24Å; D224-K229 HydrophobicContact CB-CD 4.34Å; D224-K229 IonicContact OD1-NZ 3.46Å; D224-K229 WeakPolarHBondContact OD2-CD 3.46Å; D224-K229 IonicContact OD2-NZ 3.99Å; D224-K229 PolarHBondContact OD2-NZ 3.15Å; D226-K229 HydrophobicContact CB-CD 4.12Å; D226-K229 HydrophobicContact CB-CG 4.26Å; D226-K229 PolarHBondContact O-N 3.31Å; P227-K229 PolarHBondContact O-N 2.91Å
230W98.4Very high97.4Very high16 Ų1644.8 Ų44.86%0.06123%0.228CC..  trans-67.6144.4177.4-64.8-2.1000110.4L62 E145 H148 I149 L152 N221 H222 D224 P227L62-W230 HydrophobicContact CD1-CH2 4Å; L62-W230 HydrophobicContact CD1-CZ2 3.43Å; L62-W230 VanDerWaalsContact CD1-CZ2 3.43Å; E145-W230 HydrophobicContact CG-CH2 4.02Å; E145-W230 HydrophobicContact CG-CZ2 4.42Å; H148-W230 HydrophobicContact CB-CE3 4.4Å; H148-W230 HydrophobicContact CB-CH2 3.45Å; H148-W230 VanDerWaalsContact CB-CH2 3.45Å; H148-W230 HydrophobicContact CB-CZ2 4.42Å; H148-W230 HydrophobicContact CB-CZ3 3.43Å; H148-W230 VanDerWaalsContact CB-CZ3 3.43Å; I149-W230 HydrophobicContact CG1-CH2 4.23Å; I149-W230 HydrophobicContact CG1-CZ3 3.68Å; L152-W230 HydrophobicContact CD2-CB 4.22Å; L152-W230 HydrophobicContact CD2-CE3 4.38Å; N221-W230 VanDerWaalsContact O-CA 3.32Å; N221-W230 WeakPolarHBondContact O-CA 3.45Å; N221-W230 WeakPolarHBondContact O-CB 3.2Å; H222-W230 HydrophobicContact CB-CD2 3.63Å; H222-W230 HydrophobicContact CB-CE3 3.94Å; H222-W230 HydrophobicContact CB-CG 4.13Å; H222-W230 HydrophobicContact CB-CH2 4Å; H222-W230 HydrophobicContact CB-CZ2 3.71Å; H222-W230 HydrophobicContact CB-CZ3 4.1Å; D224-W230 PolarHBondContact O-NE1 3.05Å; P227-W230 HydrophobicContact CB-CD2 4.13Å; P227-W230 HydrophobicContact CB-CE3 4.32Å; P227-W230 HydrophobicContact CB-CH2 4.47Å; P227-W230 HydrophobicContact CB-CZ2 4.28Å; P227-W230 HydrophobicContact CB-CZ3 4.48Å; P227-W230 HydrophobicContact CG-CZ2 4.19Å; P227-W230 WeakPolarHBondContact O-CB 3.35Å; P227-W230 PolarHBondContact O-N 3.16Å; P227-W230 VanDerWaalsContact O-N 3.16Å
231T97.9Very high97.4Very high69 Ų6950.2 Ų50.242%0.42325%0.249SC..EExtended strand (participates in β ladder)trans-128.3149.3-175.357.40000111.3V220 N221V220-T231 WeakPolarHBondContact CA-O 3.5Å; N221-T231 PolarHBondContact N-O 2.95Å; N221-T231 PolarHBondContact O-N 2.95Å
232V98.3Very high97.4Very high39 Ų3948.7 Ų48.724%0.23624%0.241CC..EExtended strand (participates in β ladder)trans-87.5117.9163.5-179.90000107.1I156 V218 L219 V235 V245I156-V232 HydrophobicContact CD1-CG2 3.44Å; I156-V232 VanDerWaalsContact CD1-CG2 3.44Å; I156-V232 HydrophobicContact CG1-CG2 3.95Å; V218-V232 HydrophobicContact CB-CG1 4.45Å; L219-V232 CarbonylContact O-C 3.33Å; L219-V232 WeakPolarHBondContact O-CA 3.39Å; V232-V235 HydrophobicContact CG1-CG2 3.9Å; V232-V245 HydrophobicContact CG1-CG2 4.37Å
233E98.1Very high97.4Very high58 Ų5853.7 Ų53.727%0.27127%0.267SS..EExtended strand (participates in β ladder)trans-93.1-28.9-178.4-65.7-170.5172.700112.6R197 L219 N221R197-E233 WeakPolarHBondContact CD-OE1 3.37Å; R197-E233 VanDerWaalsContact CD-OE2 3.3Å; R197-E233 WeakPolarHBondContact CD-OE2 3.33Å; R197-E233 IonicContact CZ-OE2 3.73Å; R197-E233 IonicContact NE-OE2 2.71Å; R197-E233 IonicContact NH1-OE2 3.51Å; R197-E233 PolarHBondContact NH1-OE2 3Å; L219-E233 HydrophobicContact CD2-CB 4.08Å; L219-E233 HydrophobicContact CG-CB 4.22Å; L219-E233 PolarHBondContact O-N 2.71Å; N221-E233 HydrophobicContact CB-CG 4.1Å; N221-E233 WeakPolarHBondContact CB-OE1 3.38Å; N221-E233 PolarHBondContact ND2-OE1 2.76Å
234K98.5Very high97.4Very high73 Ų7351.7 Ų51.732%0.31726%0.262SS..EExtended strand (participates in β ladder)trans-153.3152.6178.6-74.4-60.8-179.71710111.3W199 L219 F242 D243W199-K234 HydrophobicContact CH2-CB 3.8Å; W199-K234 HydrophobicContact CZ2-CB 4.18Å; L219-K234 HydrophobicContact CB-CB 4.03Å; L219-K234 HydrophobicContact CD2-CB 4.44Å; L219-K234 PolarHBondContact N-O 3.45Å; K234-F242 WeakPolarHBondContact CD-O 3.48Å; K234-D243 IonicContact NZ-OD1 3.54Å; K234-D243 PolarHBondContact NZ-OD1 2.84Å
235V98.7Very high97.4Very high0 Ų049 Ų490%025%0.248CC..EExtended strand (participates in β ladder)trans-123.6140.4167.7-173.20000108.4F216 V218 V232 Y241 F242 V245 L248F216-V235 HydrophobicContact CE2-CG1 4.02Å; F216-V235 HydrophobicContact CZ-CG1 3.98Å; V218-V235 HydrophobicContact CG1-CB 4.48Å; V218-V235 HydrophobicContact CG1-CG1 4.08Å; V218-V235 HydrophobicContact CG1-CG2 4.13Å; V232-V235 HydrophobicContact CG1-CG2 3.9Å; V235-Y241 CarbonylContact O-C 3.54Å; V235-Y241 WeakPolarHBondContact O-CA 3.42Å; V235-F242 HydrophobicContact CB-CB 4.29Å; V235-F242 PolarHBondContact N-O 2.81Å; V235-F242 PolarHBondContact O-N 2.88Å; V235-V245 HydrophobicContact CG2-CG2 3.81Å; V235-L248 HydrophobicContact CG1-CD2 3.68Å
236W98.6Very high97.5Very high4 Ų453.3 Ų53.32%0.01527%0.268CS..EExtended strand (participates in β ladder)trans-121.3128.6170.7-178.894.8000109W199 F216 E217 S239 M240 Y241 T352 P353 F478 T480W199-W236 HydrophobicContact CH2-CB 4.2Å; W199-W236 HydrophobicContact CZ3-CB 4.05Å; F216-W236 WeakPolarHBondContact CA-O 3.34Å; E217-W236 HydrophobicContact CB-CB 4.31Å; E217-W236 HydrophobicContact CB-CE3 4.35Å; E217-W236 HydrophobicContact CG-CE3 3.89Å; E217-W236 HydrophobicContact CG-CZ3 4.39Å; E217-W236 PolarHBondContact N-O 3.29Å; E217-W236 PolarHBondContact O-N 2.95Å; W236-S239 VanDerWaalsContact CZ2-CA 3.47Å; W236-M240 CarbonylContact C-O 3.55Å; W236-M240 VanDerWaalsContact CA-O 3.29Å; W236-M240 WeakPolarHBondContact CA-O 3.35Å; W236-Y241 HydrophobicContact CB-CD1 4.4Å; W236-Y241 HydrophobicContact CB-CE1 4.48Å; W236-Y241 AromaticContact CD1-CE1 3.86Å; W236-Y241 AromaticContact CD1-CE2 3.88Å; W236-Y241 AromaticContact CD1-CZ 3.78Å; W236-T352 HydrophobicContact CH2-CG2 3.53Å; W236-T352 HydrophobicContact CZ2-CG2 3.84Å; W236-T352 HydrophobicContact CZ3-CG2 4.03Å; W236-P353 HydrophobicContact CB-CG 3.7Å; W236-P353 HydrophobicContact CD2-CG 4.32Å; W236-P353 HydrophobicContact CG-CG 3.61Å; W236-F478 HydrophobicContact CH2-CB 4.48Å; W236-F478 HydrophobicContact CH2-CD1 4.28Å; W236-F478 HydrophobicContact CZ3-CB 4.46Å; W236-T480 HydrophobicContact CH2-CG2 4.07Å; W236-T480 HydrophobicContact CZ2-CG2 4.08Å
237Y98Very high97.6Very high1 Ų153 Ų530%0.00426%0.264CS..EExtended strand (participates in β ladder)trans-141.5124176.9177.6-100.9000110.2L163 T167 G215 F216 S239 M240 L248 V257 L260L163-Y237 HydrophobicContact CD2-CD2 4.2Å; L163-Y237 HydrophobicContact CD2-CE2 3.78Å; T167-Y237 HydrophobicContact CG2-CE2 4.24Å; T167-Y237 PolarHBondContact OG1-OH 3.43Å; G215-Y237 VanDerWaalsContact O-CA 3.26Å; G215-Y237 WeakPolarHBondContact O-CA 3.34Å; G215-Y237 VanDerWaalsContact O-CD2 3.28Å; G215-Y237 WeakPolarHBondContact O-CD2 3.35Å; F216-Y237 HydrophobicContact CB-CD2 4.21Å; F216-Y237 AromaticContact CD2-CD2 3.97Å; F216-Y237 HydrophobicContact CD2-CD2 3.97Å; Y237-S239 PolarHBondContact O-N 2.85Å; Y237-M240 PolarHBondContact N-O 2.64Å; Y237-M240 WeakPolarHBondContact O-CB 3.28Å; Y237-M240 PolarHBondContact O-N 3.31Å; Y237-L248 HydrophobicContact CD1-CD1 3.95Å; Y237-L248 HydrophobicContact CG-CD1 4.15Å; Y237-L248 HydrophobicContact CG-CD2 4.31Å; Y237-V257 HydrophobicContact CD1-CG1 3.76Å; Y237-V257 HydrophobicContact CE1-CG1 3.78Å; Y237-L260 HydrophobicContact CE2-CD1 4.48Å
238N93.2Very high97.7Very high23 Ų2351.8 Ų51.812%0.12326%0.257CS..THydrogen-bonded Turntrans44.558176.7-168.929.4000114.5G215 M240 E258 L260G215-N238 PolarHBondContact O-N 3.43Å; G215-N238 VanDerWaalsContact O-N 3.11Å; N238-M240 PolarHBondContact O-N 3.44Å; N238-E258 PolarHBondContact ND2-OE2 3.23Å; N238-L260 HydrophobicContact CB-CD1 3.51Å; N238-L260 HydrophobicContact CB-CG 4.04Å; N238-L260 VanDerWaalsContact CG-CD1 3.42Å; N238-L260 WeakPolarHBondContact ND2-CD2 3.48Å; N238-L260 WeakPolarHBondContact ND2-CG 3.32Å
239S94.8Very high97.7Very high54 Ų5446.4 Ų46.438%0.37823%0.233SC..THydrogen-bonded Turntrans708-179.7-39.20000116W236 Y237 T480W236-S239 VanDerWaalsContact CZ2-CA 3.47Å; Y237-S239 PolarHBondContact O-N 2.85Å; S239-T480 VanDerWaalsContact OG-CG2 3.23Å; S239-T480 WeakPolarHBondContact OG-CG2 3.33Å
240M96.7Very high97.7Very high81 Ų8146.7 Ų46.740%0.39924%0.237SC..EExtended strand (participates in β ladder)trans-118144.7177.9-61.7-178.269.300111.6W236 Y237 N238 F242 V257W236-M240 CarbonylContact C-O 3.55Å; W236-M240 VanDerWaalsContact CA-O 3.29Å; W236-M240 WeakPolarHBondContact CA-O 3.35Å; Y237-M240 PolarHBondContact N-O 2.64Å; Y237-M240 WeakPolarHBondContact O-CB 3.28Å; Y237-M240 PolarHBondContact O-N 3.31Å; N238-M240 PolarHBondContact O-N 3.44Å; M240-F242 HydrophobicContact CB-CE2 3.61Å; M240-F242 HydrophobicContact CB-CZ 3.76Å; M240-F242 HydrophobicContact CE-CZ 4.27Å; M240-F242 HydrophobicContact SD-CZ 4.42Å; M240-V257 HydrophobicContact SD-CG1 4.47Å
241Y98.3Very high97.7Very high115 Ų11549 Ų4945%0.45125%0.247SC..EExtended strand (participates in β ladder)trans-101.7146.4173.2-70.3-90.1000111.1W199 V235 W236 P353W199-Y241 HydrophobicContact CH2-CE1 4.22Å; W199-Y241 HydrophobicContact CZ2-CE1 4.33Å; V235-Y241 CarbonylContact O-C 3.54Å; V235-Y241 WeakPolarHBondContact O-CA 3.42Å; W236-Y241 HydrophobicContact CB-CD1 4.4Å; W236-Y241 HydrophobicContact CB-CE1 4.48Å; W236-Y241 AromaticContact CD1-CE1 3.86Å; W236-Y241 AromaticContact CD1-CE2 3.88Å; W236-Y241 AromaticContact CD1-CZ 3.78Å; Y241-P353 HydrophobicContact CE1-CB 4.4Å; Y241-P353 HydrophobicContact CE1-CG 3.59Å; Y241-P353 WeakPolarHBondContact OH-CG 3.41Å
242F98.6Very high97.6Very high2 Ų245.9 Ų45.91%0.00923%0.227CC..EExtended strand (participates in β ladder)trans-134.4149.7175.4-52.8-95.6000108.9K234 V235 M240 S244 E247 L248 K251 V257K234-F242 WeakPolarHBondContact CD-O 3.48Å; V235-F242 HydrophobicContact CB-CB 4.29Å; V235-F242 PolarHBondContact N-O 2.81Å; V235-F242 PolarHBondContact O-N 2.88Å; M240-F242 HydrophobicContact CB-CE2 3.61Å; M240-F242 HydrophobicContact CB-CZ 3.76Å; M240-F242 HydrophobicContact CE-CZ 4.27Å; M240-F242 HydrophobicContact SD-CZ 4.42Å; F242-S244 VanDerWaalsContact C-N 3.3Å; F242-E247 HydrophobicContact CD1-CG 4.32Å; F242-L248 HydrophobicContact CB-CB 4.21Å; F242-L248 HydrophobicContact CD1-CB 3.99Å; F242-L248 HydrophobicContact CD1-CD1 4.33Å; F242-L248 HydrophobicContact CD2-CB 4.1Å; F242-L248 HydrophobicContact CD2-CD1 3.94Å; F242-L248 HydrophobicContact CD2-CG 4.41Å; F242-L248 HydrophobicContact CE1-CB 4.42Å; F242-L248 HydrophobicContact CE1-CD1 3.94Å; F242-L248 HydrophobicContact CE2-CD1 3.57Å; F242-L248 HydrophobicContact CE2-CG 4.5Å; F242-L248 HydrophobicContact CG-CB 3.82Å; F242-L248 HydrophobicContact CG-CD1 4.33Å; F242-L248 HydrophobicContact CZ-CD1 3.56Å; F242-K251 HydrophobicContact CD1-CD 4.11Å; F242-K251 HydrophobicContact CE1-CB 4.44Å; F242-K251 HydrophobicContact CE1-CD 3.8Å; F242-V257 HydrophobicContact CE1-CG2 3.86Å; F242-V257 HydrophobicContact CZ-CG1 4.48Å; F242-V257 HydrophobicContact CZ-CG2 3.71Å
243D97.8Very high97.5Very high104 Ų10449.6 Ų49.656%0.55624%0.242SC*.SBendtrans-76.3-20.5178.4-71.3-30.5000112K234 E247K234-D243 IonicContact NZ-OD1 3.54Å; K234-D243 PolarHBondContact NZ-OD1 2.84Å; D243-E247 WeakPolarHBondContact CB-OE2 3.34Å; D243-E247 PolarHBondContact N-OE2 3.21Å
244S98Very high97.4Very high34 Ų3452.1 Ų52.124%0.23826%0.257CS..  trans-157.4168.5-177.265.30000112.4F242 E246 E247 L248F242-S244 VanDerWaalsContact C-N 3.3Å; S244-E246 VanDerWaalsContact C-N 3.34Å; S244-E246 VanDerWaalsContact CB-OE2 3.28Å; S244-E246 WeakPolarHBondContact CB-OE2 3.01Å; S244-E247 WeakPolarHBondContact OG-CB 3.48Å; S244-E247 PolarHBondContact OG-N 3.07Å; S244-E247 VanDerWaalsContact OG-N 3.14Å; S244-L248 PolarHBondContact O-N 2.97Å
245V98Very high97.2Very high4 Ų451.3 Ų51.32%0.02427%0.269CS..Hα-helixtrans-70.9-37.2175.1-177.90000109.8I156 Q159 A160 V232 V235 E247 L248 V249I156-V245 HydrophobicContact CG1-CG2 4.35Å; I156-V245 HydrophobicContact CG2-CG1 4.33Å; I156-V245 HydrophobicContact CG2-CG2 3.83Å; Q159-V245 HydrophobicContact CB-CG1 4.25Å; Q159-V245 HydrophobicContact CG-CG1 3.98Å; A160-V245 HydrophobicContact CB-CG1 4.04Å; V232-V245 HydrophobicContact CG1-CG2 4.37Å; V235-V245 HydrophobicContact CG2-CG2 3.81Å; V245-E247 PolarHBondContact O-N 3.09Å; V245-L248 PolarHBondContact O-N 2.9Å; V245-V249 HydrophobicContact CG1-CG2 4.4Å; V245-V249 WeakPolarHBondContact O-CG2 3.47Å; V245-V249 PolarHBondContact O-N 2.02Å
246E98Very high97Very high105 Ų10557.1 Ų57.149%0.49130%0.296SS..Hα-helixtrans-53.6-52.4174.7-66.967.4-161.300111.3Q159 S244 L248 V249 E250Q159-E246 PolarHBondContact NE2-OE1 3.44Å; Q159-E246 PolarHBondContact OE1-OE1 3.17Å; S244-E246 VanDerWaalsContact C-N 3.34Å; S244-E246 VanDerWaalsContact CB-OE2 3.28Å; S244-E246 WeakPolarHBondContact CB-OE2 3.01Å; E246-L248 VanDerWaalsContact C-N 3.34Å; E246-L248 PolarHBondContact O-N 2.89Å; E246-V249 PolarHBondContact O-N 2.58Å; E246-E250 WeakPolarHBondContact O-CB 3.46Å; E246-E250 PolarHBondContact O-N 2.9Å
247E98.1Very high96.8Very high45 Ų4557.1 Ų57.121%0.2130%0.297CS..Hα-helixtrans-61.1-43.9-178.4-173.7-161.1166.200111.4F242 D243 S244 V245 E250 K251F242-E247 HydrophobicContact CD1-CG 4.32Å; D243-E247 WeakPolarHBondContact CB-OE2 3.34Å; D243-E247 PolarHBondContact N-OE2 3.21Å; S244-E247 WeakPolarHBondContact OG-CB 3.48Å; S244-E247 PolarHBondContact OG-N 3.07Å; S244-E247 VanDerWaalsContact OG-N 3.14Å; V245-E247 PolarHBondContact O-N 3.09Å; E247-E250 PolarHBondContact O-N 2.8Å; E247-K251 HydrophobicContact CG-CD 4.23Å; E247-K251 WeakPolarHBondContact O-CB 3.46Å; E247-K251 WeakPolarHBondContact O-CG 3.29Å; E247-K251 PolarHBondContact O-N 2.92Å; E247-K251 WeakPolarHBondContact OE1-CE 3.46Å; E247-K251 IonicContact OE1-NZ 3.97Å; E247-K251 PolarHBondContact OE1-NZ 2.92Å
248L98.2Very high96.5Very high0 Ų063.8 Ų63.80%033%0.328CS..Hα-helixtrans-60.8-46.9176.8168.860.2000111.1L163 F216 V235 Y237 F242 S244 V245 E246 K251 Y252 V257L163-L248 HydrophobicContact CD1-CD1 3.81Å; L163-L248 HydrophobicContact CD1-CD2 3.94Å; L163-L248 HydrophobicContact CD1-CG 3.68Å; F216-L248 HydrophobicContact CD2-CD2 4.05Å; F216-L248 HydrophobicContact CE2-CD2 3.51Å; F216-L248 HydrophobicContact CZ-CD2 4.48Å; V235-L248 HydrophobicContact CG1-CD2 3.68Å; Y237-L248 HydrophobicContact CD1-CD1 3.95Å; Y237-L248 HydrophobicContact CG-CD1 4.15Å; Y237-L248 HydrophobicContact CG-CD2 4.31Å; F242-L248 HydrophobicContact CB-CB 4.21Å; F242-L248 HydrophobicContact CD1-CB 3.99Å; F242-L248 HydrophobicContact CD1-CD1 4.33Å; F242-L248 HydrophobicContact CD2-CB 4.1Å; F242-L248 HydrophobicContact CD2-CD1 3.94Å; F242-L248 HydrophobicContact CD2-CG 4.41Å; F242-L248 HydrophobicContact CE1-CB 4.42Å; F242-L248 HydrophobicContact CE1-CD1 3.94Å; F242-L248 HydrophobicContact CE2-CD1 3.57Å; F242-L248 HydrophobicContact CE2-CG 4.5Å; F242-L248 HydrophobicContact CG-CB 3.82Å; F242-L248 HydrophobicContact CG-CD1 4.33Å; F242-L248 HydrophobicContact CZ-CD1 3.56Å; S244-L248 PolarHBondContact O-N 2.97Å; V245-L248 PolarHBondContact O-N 2.9Å; E246-L248 VanDerWaalsContact C-N 3.34Å; E246-L248 PolarHBondContact O-N 2.89Å; L248-K251 PolarHBondContact O-N 2.86Å; L248-Y252 VanDerWaalsContact O-CB 3.23Å; L248-Y252 WeakPolarHBondContact O-CB 3.03Å; L248-Y252 PolarHBondContact O-N 2.84Å; L248-V257 HydrophobicContact CD1-CG2 4.47Å
249V97.8Very high96.4Very high30 Ų3067.5 Ų67.518%0.18234%0.343CS..Hα-helixtrans-63.5-45.9-179.5171.60000110.8A160 V245 E246 K251 Y252 E253A160-V249 HydrophobicContact CB-CG2 4.17Å; V245-V249 HydrophobicContact CG1-CG2 4.4Å; V245-V249 WeakPolarHBondContact O-CG2 3.47Å; V245-V249 PolarHBondContact O-N 2.02Å; E246-V249 PolarHBondContact O-N 2.58Å; V249-K251 PolarHBondContact O-N 2.99Å; V249-Y252 PolarHBondContact O-N 2.56Å; V249-E253 WeakPolarHBondContact O-CG 3.37Å; V249-E253 PolarHBondContact O-N 2.75Å
250E97.8Very high96.2Very high124 Ų12465.8 Ų65.858%0.57933%0.33SS*.Hα-helixtrans-58-50.8177.6-177.5177.3-16700111.3E246 E247 Y252 E253 L254E246-E250 WeakPolarHBondContact O-CB 3.46Å; E246-E250 PolarHBondContact O-N 2.9Å; E247-E250 PolarHBondContact O-N 2.8Å; E250-Y252 VanDerWaalsContact C-N 3.32Å; E250-Y252 PolarHBondContact O-N 3.05Å; E250-E253 PolarHBondContact O-N 2.72Å; E250-L254 HydrophobicContact CG-CD1 4.05Å; E250-L254 WeakPolarHBondContact O-CG 3.36Å; E250-L254 PolarHBondContact O-N 3.03Å
251K97.7Very high95.9Very high63 Ų6368.4 Ų68.427%0.27434%0.339SS..Hα-helixtrans-64.8-34.5178.8-72.4-179.1167.3169.60112.9F242 E247 L248 V249 G255 E256 V257F242-K251 HydrophobicContact CD1-CD 4.11Å; F242-K251 HydrophobicContact CE1-CB 4.44Å; F242-K251 HydrophobicContact CE1-CD 3.8Å; E247-K251 HydrophobicContact CG-CD 4.23Å; E247-K251 WeakPolarHBondContact O-CB 3.46Å; E247-K251 WeakPolarHBondContact O-CG 3.29Å; E247-K251 PolarHBondContact O-N 2.92Å; E247-K251 WeakPolarHBondContact OE1-CE 3.46Å; E247-K251 IonicContact OE1-NZ 3.97Å; E247-K251 PolarHBondContact OE1-NZ 2.92Å; L248-K251 PolarHBondContact O-N 2.86Å; V249-K251 PolarHBondContact O-N 2.99Å; K251-G255 PolarHBondContact O-N 3.14Å; K251-E256 HydrophobicContact CB-CB 4.19Å; K251-E256 PolarHBondContact O-N 2.71Å; K251-V257 HydrophobicContact CB-CG2 3.75Å
252Y96.9Very high95.6Very high4 Ų463.3 Ų63.32%0.01632%0.319CS..Hα-helixtrans-65.3-39.6174.5-175.6-90.8000112L163 E166 L248 V249 E250 G255 K259L163-Y252 HydrophobicContact CB-CD1 4.06Å; L163-Y252 HydrophobicContact CB-CD2 4.37Å; L163-Y252 HydrophobicContact CB-CE1 4.09Å; L163-Y252 HydrophobicContact CB-CE2 4.37Å; L163-Y252 HydrophobicContact CB-CG 4.21Å; L163-Y252 HydrophobicContact CD1-CD1 4.42Å; L163-Y252 HydrophobicContact CD1-CD2 3.59Å; L163-Y252 HydrophobicContact CD1-CE2 4.15Å; L163-Y252 HydrophobicContact CD1-CG 3.73Å; L163-Y252 HydrophobicContact CG-CD1 4.37Å; L163-Y252 HydrophobicContact CG-CD2 3.78Å; L163-Y252 HydrophobicContact CG-CE1 4.43Å; L163-Y252 HydrophobicContact CG-CE2 3.81Å; L163-Y252 HydrophobicContact CG-CG 4.06Å; E166-Y252 WeakPolarHBondContact CB-OH 3.05Å; E166-Y252 PolarHBondContact OE2-OH 2.75Å; L248-Y252 VanDerWaalsContact O-CB 3.23Å; L248-Y252 WeakPolarHBondContact O-CB 3.03Å; L248-Y252 PolarHBondContact O-N 2.84Å; V249-Y252 PolarHBondContact O-N 2.56Å; E250-Y252 VanDerWaalsContact C-N 3.32Å; E250-Y252 PolarHBondContact O-N 3.05Å; Y252-G255 PolarHBondContact O-N 3.08Å; Y252-K259 HydrophobicContact CD2-CG 4.39Å; Y252-K259 HydrophobicContact CE1-CD 4.25Å; Y252-K259 HydrophobicContact CE1-CG 4.48Å; Y252-K259 HydrophobicContact CE2-CB 4.28Å; Y252-K259 HydrophobicContact CE2-CD 4.33Å; Y252-K259 HydrophobicContact CE2-CG 3.72Å
253E95.5Very high94.9Very high117 Ų11766.1 Ų66.155%0.54734%0.338SS..Hα-helixtrans-72.2-34.5177.6-69.6-163.5141.700113.2K162 V249 E250 G255K162-E253 IonicContact NZ-OE1 3.62Å; K162-E253 PolarHBondContact NZ-OE1 3.11Å; V249-E253 WeakPolarHBondContact O-CG 3.37Å; V249-E253 PolarHBondContact O-N 2.75Å; E250-E253 PolarHBondContact O-N 2.72Å; E253-G255 PolarHBondContact O-N 2.84Å
254L96.6Very high94Very high111 Ų11168.4 Ų68.458%0.58135%0.345SS*.THydrogen-bonded Turntrans-72.4-9.8172.9-67.5173.1000113.4E250 E256E250-L254 HydrophobicContact CG-CD1 4.05Å; E250-L254 WeakPolarHBondContact O-CG 3.36Å; E250-L254 PolarHBondContact O-N 3.03Å; L254-E256 VanDerWaalsContact C-N 3.31Å; L254-E256 HydrophobicContact CB-CG 4.04Å
255G94.1Very high92.8Very high56 Ų5668.1 Ų68.158%0.57734%0.34SS*.THydrogen-bonded Turntrans74.919.2-177.500000113.9K251 Y252 E253 V257K251-G255 PolarHBondContact O-N 3.14Å; Y252-G255 PolarHBondContact O-N 3.08Å; E253-G255 PolarHBondContact O-N 2.84Å; G255-V257 VanDerWaalsContact C-N 3.31Å
256E95.3Very high91.9Very high122 Ų12272 Ų7257%0.5736%0.36SS*.  trans-81.3-13.2176.5-63.3-176.7-16800112.7K251 L254K251-E256 HydrophobicContact CB-CB 4.19Å; K251-E256 PolarHBondContact O-N 2.71Å; L254-E256 VanDerWaalsContact C-N 3.31Å; L254-E256 HydrophobicContact CB-CG 4.04Å
257V93.8Very high90.8Very high5 Ų571.6 Ų71.63%0.0336%0.362CS..SBendtrans-112.3136.5175.4-177.90000109.4Y237 M240 F242 L248 K251 G255 K259Y237-V257 HydrophobicContact CD1-CG1 3.76Å; Y237-V257 HydrophobicContact CE1-CG1 3.78Å; M240-V257 HydrophobicContact SD-CG1 4.47Å; F242-V257 HydrophobicContact CE1-CG2 3.86Å; F242-V257 HydrophobicContact CZ-CG1 4.48Å; F242-V257 HydrophobicContact CZ-CG2 3.71Å; L248-V257 HydrophobicContact CD1-CG2 4.47Å; K251-V257 HydrophobicContact CB-CG2 3.75Å; G255-V257 VanDerWaalsContact C-N 3.31Å; V257-K259 PolarHBondContact O-N 2.79Å
258E91.4Very high89.9Confident140 Ų14078.1 Ų78.165%0.65439%0.392SS*.  trans-59.7122.6174.6-174.4-176.3-174.300110.8N238 L260N238-E258 PolarHBondContact ND2-OE2 3.23Å; E258-L260 PolarHBondContact O-N 2.86Å
259K90.9Very high89.3Confident102 Ų10283.2 Ų83.244%0.44342%0.42SS..  trans-76.893.6174.6-64.8-161.4168-1560110.2E166 Y252 V257E166-K259 IonicContact OE2-NZ 3.43Å; E166-K259 PolarHBondContact OE2-NZ 2.84Å; Y252-K259 HydrophobicContact CD2-CG 4.39Å; Y252-K259 HydrophobicContact CE1-CD 4.25Å; Y252-K259 HydrophobicContact CE1-CG 4.48Å; Y252-K259 HydrophobicContact CE2-CB 4.28Å; Y252-K259 HydrophobicContact CE2-CD 4.33Å; Y252-K259 HydrophobicContact CE2-CG 3.72Å; V257-K259 PolarHBondContact O-N 2.79Å
260L90Very high89Confident18 Ų1882.6 Ų82.69%0.09442%0.415CS..  trans-61141.2167-67.9179.6000110.4T167 Y237 N238 E258 F478T167-L260 VanDerWaalsContact CA-O 3.31Å; T167-L260 WeakPolarHBondContact CA-O 3.33Å; T167-L260 HydrophobicContact CG2-CB 3.97Å; T167-L260 PolarHBondContact OG1-O 3Å; Y237-L260 HydrophobicContact CE2-CD1 4.48Å; N238-L260 HydrophobicContact CB-CD1 3.51Å; N238-L260 HydrophobicContact CB-CG 4.04Å; N238-L260 VanDerWaalsContact CG-CD1 3.42Å; N238-L260 WeakPolarHBondContact ND2-CD2 3.48Å; N238-L260 WeakPolarHBondContact ND2-CG 3.32Å; E258-L260 PolarHBondContact O-N 2.86Å; L260-F478 HydrophobicContact CD1-CE1 3.82Å; L260-F478 HydrophobicContact CD1-CE2 4.44Å; L260-F478 HydrophobicContact CD1-CZ 3.52Å; L260-F478 HydrophobicContact CD2-CZ 4.49Å
261K91.7Very high88.9Confident136 Ų13678 Ų7859%0.59139%0.393SS*.  trans-130106.8165.1-173.2177.9179.9-175.50108
262L92.6Very high88.8Confident7 Ų775 Ų754%0.03738%0.38CS..PPolyproline II helixtrans-68.7150.3176.6-57.5179.1000109.7T167 T168 I214 E264 F478 Y493T167-L262 HydrophobicContact CG2-CD1 4.41Å; T167-L262 HydrophobicContact CG2-CG 4.25Å; T167-L262 WeakPolarHBondContact O-CB 3.38Å; T167-L262 WeakPolarHBondContact O-CG 3.32Å; T167-L262 PolarHBondContact O-N 2.92Å; T168-L262 HydrophobicContact CG2-CD1 4.44Å; I214-L262 HydrophobicContact CB-CD1 3.98Å; I214-L262 HydrophobicContact CG2-CD1 4.01Å; L262-E264 PolarHBondContact O-N 2.69Å; L262-F478 HydrophobicContact CD2-CE2 3.67Å; L262-F478 HydrophobicContact CD2-CZ 4.25Å; L262-Y493 HydrophobicContact CD2-CD1 3.8Å; L262-Y493 HydrophobicContact CD2-CD2 4.25Å; L262-Y493 HydrophobicContact CD2-CE1 4.18Å; L262-Y493 HydrophobicContact CD2-CG 3.81Å
263P83.7Confident88.7Confident62 Ų6275.2 Ų75.240%0.40338%0.382SS..PPolyproline II helixtrans-51.8141.5178.1-27.134.5000111.1K204 H265 Y493K204-P263 PolarHBondContact NZ-O 3.33Å; P263-H265 PolarHBondContact O-N 2.51Å; P263-Y493 VanDerWaalsContact CD-CD2 3.49Å; P263-Y493 HydrophobicContact CG-CD2 3.92Å; P263-Y493 HydrophobicContact CG-CE2 3.6Å
264E77.2Confident88.7Confident152 Ų15276.2 Ų76.271%0.7138%0.381SS*.PPolyproline II helixtrans-59.3129.2171.6-80.4-177.2-170.600108.8L262 N266L262-E264 PolarHBondContact O-N 2.69Å; E264-N266 PolarHBondContact O-N 3.45Å
265H73.1Confident88.6Confident27 Ų2776.4 Ų76.413%0.12538%0.382CS..PPolyproline II helixtrans-77.9120.9-177.1-179.185.9000109.4F171 V206 P263 D267 L270F171-H265 HydrophobicContact CE2-CB 4.08Å; F171-H265 HydrophobicContact CZ-CB 4.36Å; V206-H265 WeakPolarHBondContact CG1-CE1 3.46Å; P263-H265 PolarHBondContact O-N 2.51Å; H265-D267 IonicContact CD2-OD1 3.44Å; H265-D267 PolarHBondContact CD2-OD1 3.49Å; H265-D267 IonicContact NE2-OD1 3.69Å; H265-D267 PolarHBondContact NE2-OD1 3.11Å; H265-L270 WeakPolarHBondContact CE1-CD2 3.34Å
266N79.7Confident88.5Confident85 Ų8579.7 Ų79.746%0.45539%0.393SS..  trans-92.6107.2168.3-176.66.2000109.1E264 E268 D269 L270E264-N266 PolarHBondContact O-N 3.45Å; N266-E268 PolarHBondContact O-N 2.9Å; N266-E268 VanDerWaalsContact O-N 3.08Å; N266-E268 PolarHBondContact OD1-N 2.98Å; N266-E268 VanDerWaalsContact OD1-N 3.11Å; N266-D269 PolarHBondContact O-N 3.33Å; N266-D269 VanDerWaalsContact O-N 3.14Å; N266-L270 VanDerWaalsContact O-CD2 3.26Å; N266-L270 WeakPolarHBondContact O-CD2 3.33Å
267D75.9Confident88.4Confident97 Ų9779.7 Ų79.752%0.51939%0.388SS..THydrogen-bonded Turntrans-59.9-19180-65.4-51.1000112.5H265H265-D267 IonicContact CD2-OD1 3.44Å; H265-D267 PolarHBondContact CD2-OD1 3.49Å; H265-D267 IonicContact NE2-OD1 3.69Å; H265-D267 PolarHBondContact NE2-OD1 3.11Å
268E79.2Confident88.2Confident182 Ų18283.4 Ų83.485%0.8543%0.427SS*.THydrogen-bonded Turntrans-92.5-9.5-179.1-58.9-174.6169.400114.2N266N266-E268 PolarHBondContact O-N 2.9Å; N266-E268 VanDerWaalsContact O-N 3.08Å; N266-E268 PolarHBondContact OD1-N 2.98Å; N266-E268 VanDerWaalsContact OD1-N 3.11Å
269D84.5Confident88.1Confident108 Ų10884.1 Ų84.158%0.57843%0.43SS*.  trans-143.270.4-174.7-17120.8000112.1N266N266-D269 PolarHBondContact O-N 3.33Å; N266-D269 VanDerWaalsContact O-N 3.14Å
270L92.1Very high88.1Confident16 Ų1682.2 Ų82.28%0.08443%0.43CS..  trans-88.6125.6178.8-57.5-174000111.5V206 E207 H265 N266 S272 T273V206-L270 HydrophobicContact CB-CD1 4.39Å; E207-L270 HydrophobicContact CB-CD1 3.98Å; H265-L270 WeakPolarHBondContact CE1-CD2 3.34Å; N266-L270 VanDerWaalsContact O-CD2 3.26Å; N266-L270 WeakPolarHBondContact O-CD2 3.33Å; L270-S272 PolarHBondContact O-N 3.47Å; L270-S272 VanDerWaalsContact O-N 3.13Å; L270-T273 HydrophobicContact CB-CG2 4.44Å; L270-T273 WeakPolarHBondContact O-CG2 3.19Å; L270-T273 PolarHBondContact O-N 3.07Å
271Y94.3Very high88.1Confident28 Ų2888.8 Ų88.811%0.1147%0.465CS..THydrogen-bonded Turntrans-62.4-22171.565.6-85000112.7I211 H212 R277 Y491 V494 I672I211-Y271 HydrophobicContact CB-CE2 4.37Å; I211-Y271 HydrophobicContact CD1-CD2 4Å; I211-Y271 HydrophobicContact CD1-CE2 3.66Å; I211-Y271 HydrophobicContact CG1-CE2 3.91Å; I211-Y271 PolarHBondContact O-OH 2.98Å; H212-Y271 AromaticContact CE1-CE1 3.26Å; H212-Y271 WeakPolarHBondContact CE1-CE1 3.32Å; H212-Y271 AromaticContact CE1-CZ 3.45Å; H212-Y271 VanDerWaalsContact CE1-CZ 3.45Å; H212-Y271 PolarHBondContact CE1-OH 2.96Å; H212-Y271 VanDerWaalsContact CE1-OH 3.3Å; H212-Y271 AromaticContact ND1-CE1 3.79Å; H212-Y271 AromaticContact ND1-CZ 3.79Å; H212-Y271 PolarHBondContact ND1-OH 3.19Å; H212-Y271 AromaticContact NE2-CE1 3.95Å; H212-Y271 AromaticContact NE2-CZ 3.79Å; Y271-R277 PolarHBondContact O-NH2 2.8Å; Y271-Y491 AromaticContact CD1-CD1 3.78Å; Y271-Y491 HydrophobicContact CD1-CD1 3.78Å; Y271-Y491 HydrophobicContact CD1-CD2 4.15Å; Y271-Y491 AromaticContact CD1-CE1 3.37Å; Y271-Y491 HydrophobicContact CD1-CE1 3.37Å; Y271-Y491 AromaticContact CD1-CE2 3.78Å; Y271-Y491 HydrophobicContact CD1-CE2 3.78Å; Y271-Y491 HydrophobicContact CD1-CG 4.15Å; Y271-Y491 AromaticContact CD1-CZ 3.36Å; Y271-Y491 HydrophobicContact CD2-CD1 4.36Å; Y271-Y491 AromaticContact CD2-CD2 3.96Å; Y271-Y491 HydrophobicContact CD2-CD2 3.96Å; Y271-Y491 HydrophobicContact CD2-CE2 4.27Å; Y271-Y491 HydrophobicContact CD2-CG 4Å; Y271-Y491 AromaticContact CE1-CD1 3.55Å; Y271-Y491 HydrophobicContact CE1-CD1 3.55Å; Y271-Y491 AromaticContact CE1-CE1 3.44Å; Y271-Y491 HydrophobicContact CE1-CE1 3.44Å; Y271-Y491 VanDerWaalsContact CE1-CE1 3.44Å; Y271-Y491 HydrophobicContact CE1-CG 4.17Å; Y271-Y491 AromaticContact CE1-CZ 3.97Å; Y271-Y491 HydrophobicContact CE2-CD1 4.14Å; Y271-Y491 HydrophobicContact CE2-CD2 4.41Å; Y271-Y491 AromaticContact CE2-CG 3.98Å; Y271-Y491 HydrophobicContact CE2-CG 3.98Å; Y271-Y491 HydrophobicContact CG-CD1 4.19Å; Y271-Y491 AromaticContact CG-CD2 3.81Å; Y271-Y491 HydrophobicContact CG-CD2 3.81Å; Y271-Y491 HydrophobicContact CG-CE1 4.05Å; Y271-Y491 AromaticContact CG-CE2 3.64Å; Y271-Y491 HydrophobicContact CG-CE2 3.64Å; Y271-Y491 HydrophobicContact CG-CG 4.08Å; Y271-Y491 AromaticContact CG-CZ 3.75Å; Y271-Y491 AromaticContact CZ-CD1 3.75Å; Y271-V494 HydrophobicContact CE2-CG2 4.42Å; Y271-V494 WeakPolarHBondContact OH-CG2 3.47Å; Y271-I672 HydrophobicContact CD2-CG2 3.78Å; Y271-I672 VanDerWaalsContact O-CG2 3.28Å; Y271-I672 WeakPolarHBondContact O-CG2 3.39Å
272S95.9Very high88.1Confident0 Ų087.8 Ų87.80%047%0.47CS..THydrogen-bonded Turntrans-85.1-8179.654.90000114.9E207 H212 L270 Y473 P673E207-S272 VanDerWaalsContact O-CB 3.27Å; E207-S272 WeakPolarHBondContact O-CB 3.36Å; E207-S272 PolarHBondContact O-OG 3.4Å; H212-S272 WeakPolarHBondContact NE2-CB 3.39Å; H212-S272 PolarHBondContact NE2-OG 2.8Å; L270-S272 PolarHBondContact O-N 3.47Å; L270-S272 VanDerWaalsContact O-N 3.13Å; S272-Y473 WeakPolarHBondContact O-CE1 3.28Å; S272-Y473 PolarHBondContact O-OH 3.35Å; S272-P673 WeakPolarHBondContact O-CB 3.42Å
273T95.7Very high87.8Confident9 Ų992 Ų926%0.05550%0.498CS..  trans-78.3154.4-179.6-169.50000112.6E207 L270 I275 R277E207-T273 WeakPolarHBondContact OE1-CA 3.27Å; E207-T273 PolarHBondContact OE1-OG1 2.87Å; E207-T273 VanDerWaalsContact OE2-CB 3.26Å; E207-T273 WeakPolarHBondContact OE2-CB 3.29Å; E207-T273 PolarHBondContact OE2-OG1 3.35Å; L270-T273 HydrophobicContact CB-CG2 4.44Å; L270-T273 WeakPolarHBondContact O-CG2 3.19Å; L270-T273 PolarHBondContact O-N 3.07Å; T273-I275 VanDerWaalsContact C-N 3.35Å; T273-I275 HydrophobicContact CG2-CB 3.78Å; T273-I275 HydrophobicContact CG2-CD1 4.5Å; T273-I275 HydrophobicContact CG2-CG1 4.28Å; T273-I275 WeakPolarHBondContact OG1-CG1 3.44Å; T273-I275 PolarHBondContact OG1-N 3.25Å; T273-I275 VanDerWaalsContact OG1-N 3.15Å; T273-R277 PolarHBondContact O-NH1 3.47Å
274Y94.9Very high88Confident137 Ų13793.7 Ų93.754%0.53751%0.507SS..  trans-82-8.1167.7-89.3-99.4000114.1E207 P276 Y473 N674E207-Y274 PolarHBondContact OE1-N 2.84Å; Y274-P276 WeakPolarHBondContact O-CD 3.47Å; Y274-Y473 HydrophobicContact CE2-CE2 4.38Å; Y274-N674 WeakPolarHBondContact CE2-OD1 3.46Å; Y274-N674 VanDerWaalsContact CZ-OD1 3.3Å; Y274-N674 PolarHBondContact OH-OD1 2.76Å
275I94.6Very high88.5Confident115 Ų11594 Ų9459%0.5951%0.514SS*.SBendtrans-55.4123.9177.3-63.8168000109.5T273 R277T273-I275 VanDerWaalsContact C-N 3.35Å; T273-I275 HydrophobicContact CG2-CB 3.78Å; T273-I275 HydrophobicContact CG2-CD1 4.5Å; T273-I275 HydrophobicContact CG2-CG1 4.28Å; T273-I275 WeakPolarHBondContact OG1-CG1 3.44Å; T273-I275 PolarHBondContact OG1-N 3.25Å; T273-I275 VanDerWaalsContact OG1-N 3.15Å; I275-R277 PolarHBondContact O-N 3.12Å
276P92.9Very high89.4Confident126 Ų12698.5 Ų98.582%0.81854%0.538SS*.  trans-58.6135.1-179.2-25.634.4000112.1Y274Y274-P276 WeakPolarHBondContact O-CD 3.47Å
277R92.4Very high89.7Confident121 Ų121102.3 Ų102.346%0.45755%0.552SS.*  trans-143.1161.5178.159.9-174.3-179.9-92.13.1110.9Y271 T273 I275Y271-R277 PolarHBondContact O-NH2 2.8Å; T273-R277 PolarHBondContact O-NH1 3.47Å; I275-R277 PolarHBondContact O-N 3.12Å
278G89.6Confident90.4Very high83 Ų83100.2 Ų100.286%0.85655%0.553SS**SBendtrans87.1-170.4-173.700000113.3
279H90.1Very high91Very high156 Ų15698.1 Ų98.172%0.72256%0.556SS**  trans-135135.8-178.5-176.641.9000110.9
280S89.6Confident91.2Very high62 Ų6298 Ų9843%0.43455%0.55SS.*  trans-97.2135.6169175.10000109.6T282 P283S280-T282 PolarHBondContact O-N 2.82Å; S280-T282 VanDerWaalsContact O-N 3.12Å; S280-T282 PolarHBondContact OG-N 3.39Å; S280-T282 PolarHBondContact OG-O 3.04Å; S280-P283 WeakPolarHBondContact O-CD 3.2Å
281N91.2Very high91.2Very high155 Ų15599.5 Ų99.583%0.82956%0.558SS**SBendtrans-62.3-17.5174.5-66.5-26.2000112.9
282T90.6Very high91Very high115 Ų115100.8 Ų100.871%0.70657%0.569SS**SBendtrans-127.574.7175.551.40000109.3S280S280-T282 PolarHBondContact O-N 2.82Å; S280-T282 VanDerWaalsContact O-N 3.12Å; S280-T282 PolarHBondContact OG-N 3.39Å; S280-T282 PolarHBondContact OG-O 3.04Å
283P85.9Confident90.8Very high96 Ų96102.2 Ų102.262%0.62358%0.575SS**  trans-67.6142.5179.629.7-33000110S280S280-P283 WeakPolarHBondContact O-CD 3.2Å
284T88.1Confident90.5Very high97 Ų97104.1 Ų104.160%0.59559%0.588SS**  trans-151.1139.9176-167.60000110.7I286T284-I286 WeakPolarHBondContact OG1-CD1 3.5Å; T284-I286 VanDerWaalsContact OG1-CG1 3.23Å; T284-I286 WeakPolarHBondContact OG1-CG1 3.38Å; T284-I286 PolarHBondContact OG1-N 2.89Å
285D87.8Confident90.2Very high158 Ų158104.2 Ų104.285%0.84559%0.593SS**  trans-106.57.2175.460.9-17.9000111.8
286I91.9Very high90Very high123 Ų123100.5 Ų100.563%0.63158%0.583SS**SBendtrans-86.4140.1177.579.6-163.9000110T284T284-I286 WeakPolarHBondContact OG1-CD1 3.5Å; T284-I286 VanDerWaalsContact OG1-CG1 3.23Å; T284-I286 WeakPolarHBondContact OG1-CG1 3.38Å; T284-I286 PolarHBondContact OG1-N 2.89Å
287H86.3Confident90Very high165 Ų16599 Ų9976%0.76457%0.565SS**  trans-63.1141.5173-69.4-67.8000111.3
288G90.6Very high90.1Very high52 Ų5299 Ų9954%0.53657%0.565SS.*  trans-65.9176.2168.100000112.7K290G288-K290 PolarHBondContact O-N 3.3Å
289P91.5Very high90.5Very high139 Ų13995.9 Ų95.990%0.90353%0.528SS*.  trans-56138.4178.6-23.433.5000112.3
290K90.3Very high90.8Very high106 Ų10691.3 Ų91.346%0.46151%0.513SS..  trans-114.8145.7176.3-65.5-64.9-171.8167.10110.6G288 E382G288-K290 PolarHBondContact O-N 3.3Å; K290-E382 WeakPolarHBondContact CD-OE1 3.26Å; K290-E382 VanDerWaalsContact CE-OE1 3.27Å; K290-E382 WeakPolarHBondContact CE-OE1 3.33Å; K290-E382 IonicContact NZ-OE1 2.71Å; K290-E382 PolarHBondContact NZ-OE1 3.33Å
291L91.8Very high91.1Very high47 Ų4790.9 Ų90.925%0.24651%0.506CS..  trans-83.8135.6176.2-172.467.4000109.8P381 I383 E409 M410L291-P381 HydrophobicContact CB-CB 4.35Å; L291-P381 HydrophobicContact CD2-CB 4.08Å; L291-P381 HydrophobicContact CD2-CG 3.86Å; L291-I383 HydrophobicContact CB-CD1 4.49Å; L291-I383 HydrophobicContact CD2-CD1 3.96Å; L291-I383 HydrophobicContact CG-CD1 3.89Å; L291-E409 VanDerWaalsContact CD2-O 3.26Å; L291-E409 WeakPolarHBondContact CD2-O 3.35Å; L291-M410 HydrophobicContact CD2-CB 3.72Å
292V90.5Very high91.2Very high55 Ų5585.8 Ų85.833%0.33348%0.478SS..  trans-135.6150.9-178.7-59.90000110.4P294 C727V292-P294 HydrophobicContact CG2-CG 4.3Å; V292-C727 WeakPolarHBondContact CB-O 3.34Å; V292-C727 WeakPolarHBondContact CG1-O 3.48Å
293E90.6Very high91.3Very high29 Ų2989.4 Ų89.414%0.13648%0.479CS..  trans-122.285.2177.9-82.6177.4173.900110.6Q295 G296 H297 I383E293-Q295 PolarHBondContact O-N 2.94Å; E293-G296 PolarHBondContact O-N 3.25Å; E293-H297 IonicContact OE1-ND1 2.92Å; E293-H297 IonicContact OE2-CE1 3.02Å; E293-H297 PolarHBondContact OE2-CE1 3.34Å; E293-H297 VanDerWaalsContact OE2-CE1 3.31Å; E293-H297 IonicContact OE2-CG 2.87Å; E293-H297 IonicContact OE2-ND1 3.79Å; E293-H297 PolarHBondContact OE2-ND1 3.08Å; E293-I383 HydrophobicContact CB-CD1 4.21Å; E293-I383 HydrophobicContact CG-CD1 3.53Å
294P89.3Confident91.8Very high50 Ų5085.4 Ų85.433%0.32545%0.452SS..THydrogen-bonded Turntrans-68.3-10.7-169.6-16.929.2000115.9V292 V724 G725 C727V292-P294 HydrophobicContact CG2-CG 4.3Å; P294-V724 HydrophobicContact CB-CG1 3.95Å; P294-V724 HydrophobicContact CG-CG1 3.98Å; P294-G725 WeakPolarHBondContact CB-O 3.35Å; P294-G725 WeakPolarHBondContact CG-O 3.38Å; P294-C727 WeakPolarHBondContact CA-SG 3.19Å
295Q89.2Confident92.2Very high139 Ų13981.4 Ų81.465%0.6543%0.427SS*.THydrogen-bonded Turntrans-119.615.8177.6-56.5-171.5-67.800111.9E293 V724E293-Q295 PolarHBondContact O-N 2.94Å; Q295-V724 HydrophobicContact CG-CG1 4.08Å
296G89.5Confident92.7Very high37 Ų3773.9 Ų73.938%0.38139%0.387SS..  trans73.7-175.7-174.800000113.7E293E293-G296 PolarHBondContact O-N 3.25Å
297H94Very high93Very high95 Ų9570.3 Ų70.344%0.4437%0.367SS..  trans-62.4137.5-177.9-56.4-46.7000112.2E293 Y299 I383E293-H297 IonicContact OE1-ND1 2.92Å; E293-H297 IonicContact OE2-CE1 3.02Å; E293-H297 PolarHBondContact OE2-CE1 3.34Å; E293-H297 VanDerWaalsContact OE2-CE1 3.31Å; E293-H297 IonicContact OE2-CG 2.87Å; E293-H297 IonicContact OE2-ND1 3.79Å; E293-H297 PolarHBondContact OE2-ND1 3.08Å; H297-Y299 HydrophobicContact CB-CD1 4.12Å; H297-Y299 HydrophobicContact CB-CE1 3.87Å; H297-Y299 HydrophobicContact CB-CE2 4.46Å; H297-Y299 PolarHBondContact CE1-OH 3.36Å; H297-Y299 AromaticContact CG-CE1 3.93Å; H297-Y299 AromaticContact CG-CZ 3.76Å; H297-Y299 AromaticContact ND1-CE1 3.67Å; H297-Y299 AromaticContact ND1-CZ 3.58Å; H297-Y299 PolarHBondContact ND1-OH 3.31Å; H297-I383 PolarHBondContact CE1-O 2.77Å; H297-I383 VanDerWaalsContact CE1-O 3.23Å
298R95Very high93.5Very high121 Ų12162.7 Ų62.746%0.45733%0.332SS..SBendtrans-99.57.8172.2-55.3-165.5-59.5156.8-7.6113.5E409 T437R298-E409 IonicContact CZ-OE1 2.69Å; R298-E409 IonicContact CZ-OE2 2.56Å; R298-E409 IonicContact NE-OE1 3.54Å; R298-E409 IonicContact NE-OE2 3.58Å; R298-E409 PolarHBondContact NE-OE2 3.44Å; R298-E409 IonicContact NH2-OE1 2.67Å; R298-E409 PolarHBondContact NH2-OE1 3.12Å; R298-E409 IonicContact NH2-OE2 3.82Å; R298-E409 PolarHBondContact NH2-OE2 3.12Å; R298-T437 PolarHBondContact NH2-OG1 3.18Å
299Y96.8Very high93.7Very high16 Ų1664.1 Ų64.16%0.06334%0.339CS..EExtended strand (participates in β ladder)trans-118.9157.2173.760.7-88.8000109.2H297 I301 E307 T385 I407 E409 L439H297-Y299 HydrophobicContact CB-CD1 4.12Å; H297-Y299 HydrophobicContact CB-CE1 3.87Å; H297-Y299 HydrophobicContact CB-CE2 4.46Å; H297-Y299 PolarHBondContact CE1-OH 3.36Å; H297-Y299 AromaticContact CG-CE1 3.93Å; H297-Y299 AromaticContact CG-CZ 3.76Å; H297-Y299 AromaticContact ND1-CE1 3.67Å; H297-Y299 AromaticContact ND1-CZ 3.58Å; H297-Y299 PolarHBondContact ND1-OH 3.31Å; Y299-I301 HydrophobicContact CD2-CD1 4Å; Y299-I301 HydrophobicContact CD2-CG1 4.01Å; Y299-I301 HydrophobicContact CE2-CD1 3.63Å; Y299-I301 HydrophobicContact CE2-CG1 4.15Å; Y299-E307 CarbonylContact C-O 3.57Å; Y299-E307 WeakPolarHBondContact CA-O 3.25Å; Y299-E307 WeakPolarHBondContact CB-O 3.1Å; Y299-T385 PolarHBondContact OH-OG1 2.89Å; Y299-T385 VanDerWaalsContact OH-OG1 3.09Å; Y299-I407 HydrophobicContact CD2-CG2 4.05Å; Y299-I407 HydrophobicContact CE2-CB 4.49Å; Y299-I407 HydrophobicContact CE2-CG2 3.84Å; Y299-I407 PolarHBondContact OH-O 3.02Å; Y299-I407 VanDerWaalsContact OH-O 3.07Å; Y299-E409 HydrophobicContact CD1-CB 4.32Å; Y299-E409 HydrophobicContact CE1-CB 4.38Å; Y299-L439 HydrophobicContact CD1-CD1 3.63Å; Y299-L439 HydrophobicContact CD2-CD1 4.23Å; Y299-L439 HydrophobicContact CE1-CD1 4.26Å; Y299-L439 HydrophobicContact CG-CD1 3.63Å
300S96.1Very high93.8Very high61 Ų6158.1 Ų58.143%0.42730%0.301SS..EExtended strand (participates in β ladder)trans-124.3139.7174.355.10000110.5V306 E307S300-V306 WeakPolarHBondContact O-CA 3.16Å; S300-E307 PolarHBondContact N-O 2.86Å; S300-E307 PolarHBondContact O-N 2.62Å
301I95.6Very high94.2Very high53 Ų5353.2 Ų53.227%0.27228%0.28SS..EExtended strand (participates in β ladder)trans-119.5129.5177-58.9161.8000108Y299 R303 F305 V306 T385 I407Y299-I301 HydrophobicContact CD2-CD1 4Å; Y299-I301 HydrophobicContact CD2-CG1 4.01Å; Y299-I301 HydrophobicContact CE2-CD1 3.63Å; Y299-I301 HydrophobicContact CE2-CG1 4.15Å; I301-R303 WeakPolarHBondContact CG2-O 3.14Å; I301-F305 WeakPolarHBondContact CA-O 3.47Å; I301-V306 HydrophobicContact CG1-CG2 4.31Å; I301-T385 HydrophobicContact CD1-CG2 3.67Å; I301-I407 HydrophobicContact CD1-CB 3.93Å; I301-I407 HydrophobicContact CD1-CD1 3.53Å; I301-I407 HydrophobicContact CD1-CG1 4.31Å; I301-I407 HydrophobicContact CD1-CG2 4.04Å; I301-I407 HydrophobicContact CG1-CD1 4.02Å
302D94.1Very high94.5Very high47 Ų4751.7 Ų51.725%0.25127%0.274SS..EExtended strand (participates in β ladder)trans-128105.3167.1179.89.5000108.6A24 H25 N304 F305A24-D302 HydrophobicContact CB-CB 4.22Å; H25-D302 IonicContact CE1-OD2 3.92Å; H25-D302 PolarHBondContact CE1-OD2 3.08Å; H25-D302 IonicContact ND1-OD2 2.92Å; H25-D302 PolarHBondContact ND1-OD2 3.4Å; H25-D302 VanDerWaalsContact ND1-OD2 3.1Å; H25-D302 IonicContact NE2-OD2 2.71Å; D302-N304 PolarHBondContact O-N 2.95Å; D302-F305 PolarHBondContact N-O 3.37Å; D302-F305 WeakPolarHBondContact O-CB 3.09Å; D302-F305 PolarHBondContact O-N 3.08Å
303R92.2Very high94.8Very high192 Ų19249.2 Ų49.273%0.72526%0.258SS*.THydrogen-bonded Turntrans53.7-109.7-172-57.2170.1-171-114.60.6110.4I301 Y315I301-R303 WeakPolarHBondContact CG2-O 3.14Å; R303-Y315 PolarHBondContact O-OH 3.49Å
304N96.4Very high95.2Very high11 Ų1147.9 Ų47.96%0.05925%0.252CS..THydrogen-bonded Turntrans-103.311-179.779.3-51.4000113.3A28 A32 D302 A314 Y315A28-N304 PolarHBondContact O-ND2 3.31Å; A28-N304 PolarHBondContact O-OD1 2.66Å; A32-N304 WeakPolarHBondContact CA-ND2 3.4Å; A32-N304 HydrophobicContact CB-CB 4.25Å; A32-N304 PolarHBondContact N-ND2 2.78Å; D302-N304 PolarHBondContact O-N 2.95Å; N304-A314 CarbonylContact O-C 3.59Å; N304-A314 WeakPolarHBondContact O-CA 3.29Å; N304-Y315 HydrophobicContact CB-CD1 4.44Å; N304-Y315 HydrophobicContact CB-CE1 4.31Å; N304-Y315 WeakPolarHBondContact CB-O 3.48Å; N304-Y315 PolarHBondContact ND2-O 2.71Å; N304-Y315 WeakPolarHBondContact O-CD1 3.14Å; N304-Y315 PolarHBondContact O-N 2.75Å
305F97.6Very high95.7Very high14 Ų1446 Ų466%0.06124%0.239CC..EExtended strand (participates in β ladder)trans-100.8138.6175-177.3-113.5000110.6A24 A28 I301 D302 E307 F313A24-F305 HydrophobicContact CB-CB 4.26Å; A24-F305 HydrophobicContact CB-CD1 3.36Å; A24-F305 HydrophobicContact CB-CE1 3.81Å; A24-F305 HydrophobicContact CB-CG 3.97Å; A28-F305 HydrophobicContact CB-CB 3.61Å; A28-F305 HydrophobicContact CB-CD2 3.93Å; A28-F305 HydrophobicContact CB-CG 4.12Å; I301-F305 WeakPolarHBondContact CA-O 3.47Å; D302-F305 PolarHBondContact N-O 3.37Å; D302-F305 WeakPolarHBondContact O-CB 3.09Å; D302-F305 PolarHBondContact O-N 3.08Å; F305-E307 HydrophobicContact CD1-CG 4.07Å; F305-E307 HydrophobicContact CE1-CG 3.21Å; F305-E307 HydrophobicContact CZ-CG 3.53Å; F305-F313 WeakPolarHBondContact CA-O 3.5Å; F305-F313 VanDerWaalsContact CD2-O 3.27Å; F305-F313 WeakPolarHBondContact CD2-O 3.41Å
306V98.1Very high96.1Very high0 Ų039.6 Ų39.60%021%0.209CC..EExtended strand (participates in β ladder)trans-130.3135-179.6-1750000109.7S300 I301 S312 F313 Y315 I407 L439S300-V306 WeakPolarHBondContact O-CA 3.16Å; I301-V306 HydrophobicContact CG1-CG2 4.31Å; V306-S312 VanDerWaalsContact O-CA 3.3Å; V306-S312 WeakPolarHBondContact O-CA 3.48Å; V306-F313 HydrophobicContact CB-CD1 4.44Å; V306-F313 HydrophobicContact CB-CD2 4.28Å; V306-F313 HydrophobicContact CB-CE1 3.92Å; V306-F313 HydrophobicContact CB-CE2 3.73Å; V306-F313 HydrophobicContact CB-CZ 3.54Å; V306-F313 HydrophobicContact CG1-CE1 3.98Å; V306-F313 HydrophobicContact CG1-CE2 4.38Å; V306-F313 HydrophobicContact CG1-CZ 3.7Å; V306-F313 HydrophobicContact CG2-CD2 4.49Å; V306-F313 HydrophobicContact CG2-CE2 3.77Å; V306-F313 HydrophobicContact CG2-CZ 3.93Å; V306-F313 PolarHBondContact N-O 3.46Å; V306-F313 PolarHBondContact O-N 3.48Å; V306-Y315 HydrophobicContact CG2-CD1 3.81Å; V306-Y315 HydrophobicContact CG2-CE1 3.79Å; V306-I407 HydrophobicContact CG2-CD1 4.01Å; V306-L439 HydrophobicContact CG1-CD2 3.75Å
307E97.2Very high96.5Very high47 Ų4737.9 Ų37.922%0.2219%0.191CC..EExtended strand (participates in β ladder)trans-121.8136.3168.6-57.7-171.998.800110.5T20 Y299 S300 F305 W311T20-E307 WeakPolarHBondContact CB-OE1 3.43Å; T20-E307 WeakPolarHBondContact CG2-OE1 3.48Å; Y299-E307 CarbonylContact C-O 3.57Å; Y299-E307 WeakPolarHBondContact CA-O 3.25Å; Y299-E307 WeakPolarHBondContact CB-O 3.1Å; S300-E307 PolarHBondContact N-O 2.86Å; S300-E307 PolarHBondContact O-N 2.62Å; F305-E307 HydrophobicContact CD1-CG 4.07Å; F305-E307 HydrophobicContact CE1-CG 3.21Å; F305-E307 HydrophobicContact CZ-CG 3.53Å; E307-W311 WeakPolarHBondContact CA-O 3.17Å
308Y97.1Very high96.8Very high6 Ų634.3 Ų34.32%0.02417%0.174CC..EExtended strand (participates in β ladder)trans-156116.6179.4165.9-113.3000111.4G310 W311 E409 T437 L439Y308-G310 PolarHBondContact O-N 3.15Å; Y308-W311 AromaticContact CD1-CD1 3.77Å; Y308-W311 PolarHBondContact N-O 3.06Å; Y308-W311 WeakPolarHBondContact O-CA 3.19Å; Y308-W311 VanDerWaalsContact O-CB 3.29Å; Y308-W311 WeakPolarHBondContact O-CB 3.37Å; Y308-W311 PolarHBondContact O-N 3.3Å; Y308-E409 VanDerWaalsContact CE2-OE1 3.22Å; Y308-E409 WeakPolarHBondContact CE2-OE1 3.33Å; Y308-E409 PolarHBondContact OH-OE1 3.18Å; Y308-T437 PolarHBondContact OH-O 3.31Å; Y308-T437 VanDerWaalsContact OH-O 3.1Å; Y308-T437 PolarHBondContact OH-OG1 3.44Å; Y308-L439 HydrophobicContact CD1-CB 3.35Å; Y308-L439 HydrophobicContact CD1-CD2 4.18Å; Y308-L439 HydrophobicContact CD1-CG 4.27Å; Y308-L439 HydrophobicContact CD2-CB 4.35Å; Y308-L439 HydrophobicContact CE1-CB 3.61Å; Y308-L439 HydrophobicContact CG-CB 3.76Å; Y308-L439 HydrophobicContact CG-CD1 4.32Å; Y308-L439 HydrophobicContact CG-CD2 4.09Å; Y308-L439 HydrophobicContact CG-CG 4.28Å
309A94.1Very high96.9Very high82 Ų8228.8 Ų28.868%0.67815%0.154SC*.THydrogen-bonded Turntrans51.8-111.2-176.100000111.7
310G94.8Very high97Very high12 Ų1228.2 Ų28.212%0.12415%0.152CC..THydrogen-bonded Turntrans-87-12.8173.900000114.2Y308 F330 N331Y308-G310 PolarHBondContact O-N 3.15Å; G310-F330 CarbonylContact O-C 3.57Å; G310-F330 VanDerWaalsContact O-CA 3.26Å; G310-F330 WeakPolarHBondContact O-CA 3.43Å; G310-N331 WeakPolarHBondContact CA-OD1 3.46Å; G310-N331 PolarHBondContact O-N 3.33Å
311W98.2Very high97.1Very high3 Ų325.3 Ų25.31%0.01113%0.132CC..EExtended strand (participates in β ladder)trans-82.7141.6-173.6-63102.5000113E307 Y308 L328 R329 F330 I335 F458 Y459 G462 V463 V464E307-W311 WeakPolarHBondContact CA-O 3.17Å; Y308-W311 AromaticContact CD1-CD1 3.77Å; Y308-W311 PolarHBondContact N-O 3.06Å; Y308-W311 WeakPolarHBondContact O-CA 3.19Å; Y308-W311 VanDerWaalsContact O-CB 3.29Å; Y308-W311 WeakPolarHBondContact O-CB 3.37Å; Y308-W311 PolarHBondContact O-N 3.3Å; W311-L328 HydrophobicContact CE3-CD1 3.59Å; W311-L328 HydrophobicContact CE3-CG 4.29Å; W311-L328 HydrophobicContact CZ3-CD1 3.73Å; W311-L328 HydrophobicContact CZ3-CD2 4.2Å; W311-L328 HydrophobicContact CZ3-CG 3.99Å; W311-R329 WeakPolarHBondContact CA-O 3.2Å; W311-F330 AromaticContact CD2-CD2 3.64Å; W311-F330 HydrophobicContact CD2-CD2 3.64Å; W311-F330 HydrophobicContact CD2-CE2 4.28Å; W311-F330 AromaticContact CE2-CD2 3.5Å; W311-F330 AromaticContact CE2-CE2 3.83Å; W311-F330 HydrophobicContact CE3-CB 4.28Å; W311-F330 AromaticContact CE3-CD2 3.93Å; W311-F330 HydrophobicContact CE3-CD2 3.93Å; W311-F330 HydrophobicContact CG-CD2 4.16Å; W311-F330 AromaticContact CH2-CD2 3.98Å; W311-F330 HydrophobicContact CH2-CD2 3.98Å; W311-F330 AromaticContact CZ2-CD2 3.72Å; W311-F330 HydrophobicContact CZ2-CD2 3.72Å; W311-F330 HydrophobicContact CZ2-CE2 4.15Å; W311-F330 HydrophobicContact CZ3-CB 4.14Å; W311-F330 HydrophobicContact CZ3-CD2 4.09Å; W311-F330 AromaticContact NE1-CD2 3.89Å; W311-F330 AromaticContact NE1-CE2 3.77Å; W311-I335 HydrophobicContact CH2-CD1 4.11Å; W311-I335 HydrophobicContact CZ3-CD1 3.72Å; W311-F458 HydrophobicContact CD2-CB 4.09Å; W311-F458 HydrophobicContact CD2-CD1 4.07Å; W311-F458 HydrophobicContact CE3-CD1 4.16Å; W311-F458 HydrophobicContact CG-CB 3.97Å; W311-F458 HydrophobicContact CG-CD1 4.44Å; W311-Y459 WeakPolarHBondContact CZ2-O 3.22Å; W311-Y459 PolarHBondContact NE1-O 2.97Å; W311-G462 VanDerWaalsContact CH2-C 3.5Å; W311-G462 WeakPolarHBondContact CH2-O 3.4Å; W311-G462 VanDerWaalsContact CZ2-CA 3.4Å; W311-V463 VanDerWaalsContact CZ2-O 3.31Å; W311-V463 WeakPolarHBondContact CZ2-O 3.05Å; W311-V464 HydrophobicContact CE3-CG2 4.42Å; W311-V464 HydrophobicContact CH2-CG2 3.23Å; W311-V464 HydrophobicContact CZ2-CG2 3.83Å; W311-V464 HydrophobicContact CZ3-CG2 3.58Å
312S97.7Very high97.2Very high16 Ų1622.8 Ų22.811%0.11212%0.119CC..EExtended strand (participates in β ladder)trans-142135.7161.165.80000109.8V306 R329V306-S312 VanDerWaalsContact O-CA 3.3Å; V306-S312 WeakPolarHBondContact O-CA 3.48Å; S312-R329 PolarHBondContact N-O 2.97Å; S312-R329 VanDerWaalsContact N-O 3.11Å; S312-R329 PolarHBondContact O-N 3.19Å
313F98.3Very high97.4Very high2 Ų220.7 Ų20.71%0.00911%0.107CC..EExtended strand (participates in β ladder)trans-158.1161.2178.159.5-90.3000111.9F305 V306 V325 L328 L439 L441 F458F305-F313 WeakPolarHBondContact CA-O 3.5Å; F305-F313 VanDerWaalsContact CD2-O 3.27Å; F305-F313 WeakPolarHBondContact CD2-O 3.41Å; V306-F313 HydrophobicContact CB-CD1 4.44Å; V306-F313 HydrophobicContact CB-CD2 4.28Å; V306-F313 HydrophobicContact CB-CE1 3.92Å; V306-F313 HydrophobicContact CB-CE2 3.73Å; V306-F313 HydrophobicContact CB-CZ 3.54Å; V306-F313 HydrophobicContact CG1-CE1 3.98Å; V306-F313 HydrophobicContact CG1-CE2 4.38Å; V306-F313 HydrophobicContact CG1-CZ 3.7Å; V306-F313 HydrophobicContact CG2-CD2 4.49Å; V306-F313 HydrophobicContact CG2-CE2 3.77Å; V306-F313 HydrophobicContact CG2-CZ 3.93Å; V306-F313 PolarHBondContact N-O 3.46Å; V306-F313 PolarHBondContact O-N 3.48Å; F313-V325 HydrophobicContact CB-CG1 3.77Å; F313-V325 HydrophobicContact CD2-CG1 3.86Å; F313-V325 HydrophobicContact CG-CG1 3.97Å; F313-L328 HydrophobicContact CB-CD1 3.95Å; F313-L328 HydrophobicContact CD1-CD1 4.2Å; F313-L328 HydrophobicContact CG-CD1 4.36Å; F313-L439 HydrophobicContact CE1-CD2 4.06Å; F313-L439 HydrophobicContact CZ-CD2 4.06Å; F313-L441 HydrophobicContact CE2-CD2 4.13Å; F313-F458 HydrophobicContact CD1-CD1 4.36Å; F313-F458 AromaticContact CD1-CE1 3.92Å; F313-F458 HydrophobicContact CD1-CE1 3.92Å; F313-F458 HydrophobicContact CD1-CE2 4.41Å; F313-F458 AromaticContact CD1-CZ 3.94Å; F313-F458 HydrophobicContact CD1-CZ 3.94Å; F313-F458 HydrophobicContact CD2-CZ 4.31Å; F313-F458 HydrophobicContact CE1-CD1 4.13Å; F313-F458 AromaticContact CE1-CD2 3.88Å; F313-F458 HydrophobicContact CE1-CD2 3.88Å; F313-F458 AromaticContact CE1-CE1 3.84Å; F313-F458 HydrophobicContact CE1-CE1 3.84Å; F313-F458 AromaticContact CE1-CE2 3.57Å; F313-F458 HydrophobicContact CE1-CE2 3.57Å; F313-F458 HydrophobicContact CE1-CG 4.14Å; F313-F458 AromaticContact CE1-CZ 3.54Å; F313-F458 HydrophobicContact CE1-CZ 3.54Å; F313-F458 HydrophobicContact CE2-CE2 4.12Å; F313-F458 AromaticContact CE2-CZ 3.95Å; F313-F458 HydrophobicContact CE2-CZ 3.95Å; F313-F458 HydrophobicContact CG-CE1 4.46Å; F313-F458 HydrophobicContact CG-CZ 4.31Å; F313-F458 HydrophobicContact CZ-CD2 4.03Å; F313-F458 HydrophobicContact CZ-CE1 4.31Å; F313-F458 AromaticContact CZ-CE2 3.38Å; F313-F458 HydrophobicContact CZ-CE2 3.38Å; F313-F458 AromaticContact CZ-CZ 3.54Å; F313-F458 HydrophobicContact CZ-CZ 3.54Å
314A98.4Very high97.7Very high2 Ų211.7 Ų11.72%0.0177%0.074CC..EExtended strand (participates in β ladder)trans-101.5153.9164.900000110.3A28 F31 N304 V325 F326A28-A314 HydrophobicContact CB-CB 3.76Å; F31-A314 HydrophobicContact CB-CB 4.36Å; F31-A314 HydrophobicContact CD2-CB 3.94Å; N304-A314 CarbonylContact O-C 3.59Å; N304-A314 WeakPolarHBondContact O-CA 3.29Å; A314-V325 CarbonylContact O-C 3.59Å; A314-V325 WeakPolarHBondContact O-CA 3.42Å; A314-F326 HydrophobicContact CB-CB 4.26Å; A314-F326 PolarHBondContact N-O 2.88Å; A314-F326 PolarHBondContact O-N 2.88Å
315Y98.6Very high97.8Very high11 Ų1111.2 Ų11.24%0.0437%0.071CC..EExtended strand (participates in β ladder)trans-131165.8173.470.9-90.8000112.4R303 N304 V306 Q324 L405 I407 L441R303-Y315 PolarHBondContact O-OH 3.49Å; N304-Y315 HydrophobicContact CB-CD1 4.44Å; N304-Y315 HydrophobicContact CB-CE1 4.31Å; N304-Y315 WeakPolarHBondContact CB-O 3.48Å; N304-Y315 PolarHBondContact ND2-O 2.71Å; N304-Y315 WeakPolarHBondContact O-CD1 3.14Å; N304-Y315 PolarHBondContact O-N 2.75Å; V306-Y315 HydrophobicContact CG2-CD1 3.81Å; V306-Y315 HydrophobicContact CG2-CE1 3.79Å; Y315-Q324 VanDerWaalsContact CA-O 3.26Å; Y315-Q324 WeakPolarHBondContact CA-O 3.25Å; Y315-L405 HydrophobicContact CD2-CD1 3.98Å; Y315-L405 HydrophobicContact CE2-CD1 3.87Å; Y315-L405 HydrophobicContact CE2-CD2 3.87Å; Y315-I407 HydrophobicContact CE1-CD1 3.92Å; Y315-L441 HydrophobicContact CD1-CD1 4.37Å; Y315-L441 HydrophobicContact CD2-CD1 4.39Å; Y315-L441 HydrophobicContact CG-CD1 4.23Å; Y315-L441 HydrophobicContact CG-CD2 4.24Å
316R98.4Very high97.9Very high3 Ų310.6 Ų10.61%0.0117%0.068CC..EExtended strand (participates in β ladder)trans-157.5165.7166.266.3171.4-64.8-160.6-0.1110.8F31 D33 L72 Q324 F326F31-R316 WeakPolarHBondContact O-CB 3.5Å; F31-R316 WeakPolarHBondContact O-CD 3.48Å; D33-R316 IonicContact OD1-CZ 2.68Å; D33-R316 IonicContact OD1-NE 2.79Å; D33-R316 PolarHBondContact OD1-NE 3.4Å; D33-R316 IonicContact OD1-NH2 3.15Å; D33-R316 PolarHBondContact OD1-NH2 3.06Å; D33-R316 WeakPolarHBondContact OD2-CB 3.26Å; L72-R316 PolarHBondContact O-NH1 2.7Å; R316-Q324 VanDerWaalsContact CD-OE1 3.3Å; R316-Q324 HydrophobicContact CG-CB 3.91Å; R316-Q324 HydrophobicContact CG-CG 4.3Å; R316-Q324 PolarHBondContact N-O 2.82Å; R316-Q324 PolarHBondContact O-N 3.04Å; R316-F326 HydrophobicContact CG-CD2 4.24Å; R316-F326 HydrophobicContact CG-CE2 3.65Å
317V98.7Very high97.9Very high1 Ų111.2 Ų11.21%0.0067%0.072CC..EExtended strand (participates in β ladder)trans-122.996.7172.1-174.80000108.1D33 S319 L323 T371 L389 L405D33-V317 PolarHBondContact OD2-N 3.34Å; V317-S319 PolarHBondContact O-N 3.28Å; V317-L323 HydrophobicContact CG2-CD1 3.74Å; V317-T371 HydrophobicContact CG1-CG2 3.88Å; V317-L389 HydrophobicContact CB-CD1 3.81Å; V317-L389 HydrophobicContact CB-CD2 4.41Å; V317-L389 HydrophobicContact CG1-CD1 3.98Å; V317-L389 HydrophobicContact CG2-CD1 3.7Å; V317-L389 HydrophobicContact CG2-CD2 4.19Å; V317-L405 HydrophobicContact CG2-CD1 3.71Å
318R98.7Very high97.9Very high21 Ų219 Ų98%0.0796%0.062CC..EExtended strand (participates in β ladder)trans-69.7115.5-176.6179-179.6177.2-135.6-1.8109.7E71 S320 A321 G322E71-R318 IonicContact OE1-CZ 2.97Å; E71-R318 IonicContact OE1-NE 3.1Å; E71-R318 PolarHBondContact OE1-NE 2.9Å; E71-R318 IonicContact OE1-NH2 2.71Å; E71-R318 PolarHBondContact OE1-NH2 2.91Å; E71-R318 VanDerWaalsContact OE2-CG 3.24Å; E71-R318 WeakPolarHBondContact OE2-CG 3.09Å; E71-R318 IonicContact OE2-NE 2.67Å; R318-S320 PolarHBondContact NE-OG 3.31Å; R318-S320 PolarHBondContact NH1-OG 2.82Å; R318-S320 PolarHBondContact NH2-OG 3.47Å; R318-S320 PolarHBondContact O-N 3.23Å; R318-A321 CarbonylContact O-C 3.58Å; R318-A321 PolarHBondContact O-N 3.26Å; R318-G322 PolarHBondContact N-O 3.34Å; R318-G322 PolarHBondContact O-N 3.31Å
319S98.7Very high97.9Very high5 Ų59.5 Ų9.54%0.0356%0.063CC..THydrogen-bonded Turntrans-43.9-44.3-179.6-56.10000114V317 A321 A366 G368 T369 H391V317-S319 PolarHBondContact O-N 3.28Å; S319-A321 VanDerWaalsContact C-N 3.31Å; S319-A321 PolarHBondContact O-N 2.71Å; S319-A366 CarbonylContact O-C 3.54Å; S319-G368 CarbonylContact O-C 3.54Å; S319-G368 WeakPolarHBondContact O-CA 3.46Å; S319-G368 PolarHBondContact O-N 3.04Å; S319-G368 VanDerWaalsContact O-N 3.12Å; S319-T369 PolarHBondContact O-N 2.86Å; S319-H391 PolarHBondContact OG-ND1 3.03Å
320S98.2Very high98.1Very high3 Ų35.8 Ų5.82%0.0213%0.032CC..THydrogen-bonded Turntrans-71.2-18.7-178.875.80000115.9E71 R318E71-S320 WeakPolarHBondContact OE2-CB 3.42Å; E71-S320 PolarHBondContact OE2-N 3.01Å; E71-S320 PolarHBondContact OE2-OG 3.11Å; R318-S320 PolarHBondContact NE-OG 3.31Å; R318-S320 PolarHBondContact NH1-OG 2.82Å; R318-S320 PolarHBondContact NH2-OG 3.47Å; R318-S320 PolarHBondContact O-N 3.23Å
321A97.2Very high98.1Very high1 Ų110.1 Ų10.11%0.0085%0.052CC..THydrogen-bonded Turntrans-144.3-45.6-168.400000115R318 S319 L341 M367R318-A321 CarbonylContact O-C 3.58Å; R318-A321 PolarHBondContact O-N 3.26Å; S319-A321 VanDerWaalsContact C-N 3.31Å; S319-A321 PolarHBondContact O-N 2.71Å; A321-L341 WeakPolarHBondContact O-CD2 3.28Å; A321-M367 WeakPolarHBondContact O-CG 2.94Å
322G98Very high97.8Very high0 Ų012.2 Ų12.20%08%0.075CC..EExtended strand (participates in β ladder)trans133.3-150.5176.100000115R318 Q324R318-G322 PolarHBondContact N-O 3.34Å; R318-G322 PolarHBondContact O-N 3.31Å; G322-Q324 WeakPolarHBondContact O-CG 3.33Å
323L98.8Very high97.7Very high2 Ų214.9 Ų14.91%0.019%0.085CC..EExtended strand (participates in β ladder)trans-67.2137.4-165.6-168.561.1000113.8V317 L341 L405 L441 T443 W454 F456V317-L323 HydrophobicContact CG2-CD1 3.74Å; L323-L341 PolarHBondContact O-N 2.89Å; L323-L405 HydrophobicContact CD1-CD1 3.83Å; L323-L441 HydrophobicContact CD1-CD2 4.03Å; L323-L441 HydrophobicContact CD1-CG 4.3Å; L323-L441 HydrophobicContact CD2-CD2 4.35Å; L323-L441 HydrophobicContact CD2-CG 4.31Å; L323-L441 HydrophobicContact CG-CD2 4.46Å; L323-T443 HydrophobicContact CB-CG2 3.78Å; L323-T443 HydrophobicContact CD1-CG2 4.24Å; L323-T443 HydrophobicContact CD2-CG2 4.08Å; L323-T443 HydrophobicContact CG-CG2 4.26Å; L323-W454 HydrophobicContact CD2-CB 4.3Å; L323-F456 HydrophobicContact CB-CE2 4.44Å; L323-F456 HydrophobicContact CD2-CD2 3.6Å; L323-F456 HydrophobicContact CD2-CE2 3.9Å; L323-F456 HydrophobicContact CG-CD2 3.98Å; L323-F456 HydrophobicContact CG-CE2 3.85Å
324Q98.9Very high97.6Very high4 Ų415.7 Ų15.72%0.0199%0.088CC..EExtended strand (participates in β ladder)trans-143.1144.1-179.5-46.3-170.9-39.400111.3Y315 R316 G322 F326 I339 S340Y315-Q324 VanDerWaalsContact CA-O 3.26Å; Y315-Q324 WeakPolarHBondContact CA-O 3.25Å; R316-Q324 VanDerWaalsContact CD-OE1 3.3Å; R316-Q324 HydrophobicContact CG-CB 3.91Å; R316-Q324 HydrophobicContact CG-CG 4.3Å; R316-Q324 PolarHBondContact N-O 2.82Å; R316-Q324 PolarHBondContact O-N 3.04Å; G322-Q324 WeakPolarHBondContact O-CG 3.33Å; Q324-F326 HydrophobicContact CB-CD2 4.31Å; Q324-F326 HydrophobicContact CB-CE2 3.54Å; Q324-F326 HydrophobicContact CB-CZ 4.19Å; Q324-F326 HydrophobicContact CG-CE2 4.47Å; Q324-I339 WeakPolarHBondContact CA-O 2.93Å; Q324-S340 VanDerWaalsContact CG-CB 3.49Å
325V98.9Very high97.6Very high1 Ų115.6 Ų15.61%0.0069%0.088CC..EExtended strand (participates in β ladder)trans-119.5135.2174.71750000109.3F313 A314 L328 E338 I339 L441 F456 F458F313-V325 HydrophobicContact CB-CG1 3.77Å; F313-V325 HydrophobicContact CD2-CG1 3.86Å; F313-V325 HydrophobicContact CG-CG1 3.97Å; A314-V325 CarbonylContact O-C 3.59Å; A314-V325 WeakPolarHBondContact O-CA 3.42Å; V325-L328 HydrophobicContact CG1-CB 4.33Å; V325-L328 HydrophobicContact CG1-CD1 4.37Å; V325-E338 CarbonylContact O-C 3.06Å; V325-E338 WeakPolarHBondContact O-CA 3.42Å; V325-I339 PolarHBondContact N-O 2.9Å; V325-I339 PolarHBondContact O-N 2.94Å; V325-L441 HydrophobicContact CG2-CD2 3.9Å; V325-F456 HydrophobicContact CB-CE1 4.45Å; V325-F456 HydrophobicContact CB-CZ 4.49Å; V325-F456 HydrophobicContact CG2-CB 4.44Å; V325-F456 HydrophobicContact CG2-CD1 3.97Å; V325-F456 HydrophobicContact CG2-CD2 3.73Å; V325-F456 HydrophobicContact CG2-CE1 4.1Å; V325-F456 HydrophobicContact CG2-CE2 3.88Å; V325-F456 HydrophobicContact CG2-CG 3.79Å; V325-F456 HydrophobicContact CG2-CZ 4.05Å; V325-F458 HydrophobicContact CG1-CZ 4.49Å; V325-F458 HydrophobicContact CG2-CZ 4.27Å
326F98.7Very high97.6Very high1 Ų115.1 Ų15.10%0.0049%0.086CC..EExtended strand (participates in β ladder)trans-126.8151.3-175.9-70.9-86.1000112.3F31 L74 A314 R316 Q324 L328 Y337 E338F31-F326 HydrophobicContact CB-CB 4.2Å; F31-F326 HydrophobicContact CB-CD2 4.01Å; F31-F326 HydrophobicContact CB-CG 4.09Å; F31-F326 HydrophobicContact CD1-CB 4.02Å; F31-F326 AromaticContact CD1-CD1 3.68Å; F31-F326 HydrophobicContact CD1-CD1 3.68Å; F31-F326 HydrophobicContact CD1-CD2 4.31Å; F31-F326 HydrophobicContact CD1-CE1 4.23Å; F31-F326 AromaticContact CD1-CG 3.73Å; F31-F326 HydrophobicContact CD1-CG 3.73Å; F31-F326 HydrophobicContact CD2-CB 3.76Å; F31-F326 HydrophobicContact CD2-CG 4.34Å; F31-F326 HydrophobicContact CE1-CB 4.33Å; F31-F326 AromaticContact CE1-CD1 3.84Å; F31-F326 HydrophobicContact CE1-CD1 3.84Å; F31-F326 HydrophobicContact CE1-CG 4.21Å; F31-F326 HydrophobicContact CE2-CB 4.08Å; F31-F326 HydrophobicContact CG-CB 3.72Å; F31-F326 HydrophobicContact CG-CD1 4.24Å; F31-F326 HydrophobicContact CG-CD2 4.23Å; F31-F326 AromaticContact CG-CG 3.8Å; F31-F326 HydrophobicContact CG-CG 3.8Å; F31-F326 HydrophobicContact CZ-CB 4.35Å; F31-F326 HydrophobicContact CZ-CD1 4.5Å; L74-F326 HydrophobicContact CD1-CE1 3.91Å; L74-F326 HydrophobicContact CD1-CZ 3.56Å; L74-F326 HydrophobicContact CD2-CE1 4.3Å; L74-F326 HydrophobicContact CD2-CZ 4.07Å; L74-F326 HydrophobicContact CG-CZ 4.5Å; A314-F326 HydrophobicContact CB-CB 4.26Å; A314-F326 PolarHBondContact N-O 2.88Å; A314-F326 PolarHBondContact O-N 2.88Å; R316-F326 HydrophobicContact CG-CD2 4.24Å; R316-F326 HydrophobicContact CG-CE2 3.65Å; Q324-F326 HydrophobicContact CB-CD2 4.31Å; Q324-F326 HydrophobicContact CB-CE2 3.54Å; Q324-F326 HydrophobicContact CB-CZ 4.19Å; Q324-F326 HydrophobicContact CG-CE2 4.47Å; F326-L328 VanDerWaalsContact C-N 3.26Å; F326-L328 PolarHBondContact O-N 3.01Å; F326-Y337 CarbonylContact C-O 3.41Å; F326-Y337 VanDerWaalsContact CA-O 3.26Å; F326-Y337 WeakPolarHBondContact CA-O 3.49Å; F326-E338 HydrophobicContact CD1-CB 4.02Å; F326-E338 HydrophobicContact CD1-CG 4.12Å; F326-E338 HydrophobicContact CE1-CB 3.82Å; F326-E338 HydrophobicContact CE1-CG 3.51Å; F326-E338 HydrophobicContact CZ-CG 3.86Å
327D97.4Very high97.6Very high13 Ų1315.3 Ų15.37%0.079%0.087CC..EExtended strand (participates in β ladder)trans46.550.5178.7-166.533.3000112F31 L84 R329 R334 Y337F31-D327 HydrophobicContact CE2-CB 4.37Å; L84-D327 HydrophobicContact CD1-CB 4.23Å; D327-R329 VanDerWaalsContact CG-NE 3.33Å; D327-R329 WeakPolarHBondContact O-CG 3.23Å; D327-R329 PolarHBondContact O-N 2.76Å; D327-R329 IonicContact OD1-CZ 3.03Å; D327-R329 IonicContact OD1-NE 3.99Å; D327-R329 PolarHBondContact OD1-NE 2.9Å; D327-R329 VanDerWaalsContact OD1-NE 3.07Å; D327-R329 IonicContact OD1-NH2 2.71Å; D327-R329 PolarHBondContact OD1-NH2 2.86Å; D327-R329 IonicContact OD2-CZ 3.4Å; D327-R329 IonicContact OD2-NE 3.04Å; D327-R329 PolarHBondContact OD2-NE 3.16Å; D327-R329 IonicContact OD2-NH2 2.9Å; D327-R329 PolarHBondContact OD2-NH2 3.37Å; D327-R334 IonicContact OD1-CZ 3.32Å; D327-R334 IonicContact OD1-NE 3.25Å; D327-R334 PolarHBondContact OD1-NE 2.89Å; D327-R334 IonicContact OD1-NH2 2.82Å; D327-R334 PolarHBondContact OD1-NH2 3.2Å; D327-R334 IonicContact OD2-NH2 2.75Å; D327-Y337 PolarHBondContact N-O 2.86Å
328L98.3Very high97.6Very high1 Ų115.8 Ų15.81%0.0059%0.089CC..EExtended strand (participates in β ladder)trans-71.5117.8-178.3177.267.5000109.8W311 F313 V325 F326 I335 A336 I339 F458 V464W311-L328 HydrophobicContact CE3-CD1 3.59Å; W311-L328 HydrophobicContact CE3-CG 4.29Å; W311-L328 HydrophobicContact CZ3-CD1 3.73Å; W311-L328 HydrophobicContact CZ3-CD2 4.2Å; W311-L328 HydrophobicContact CZ3-CG 3.99Å; F313-L328 HydrophobicContact CB-CD1 3.95Å; F313-L328 HydrophobicContact CD1-CD1 4.2Å; F313-L328 HydrophobicContact CG-CD1 4.36Å; V325-L328 HydrophobicContact CG1-CB 4.33Å; V325-L328 HydrophobicContact CG1-CD1 4.37Å; F326-L328 VanDerWaalsContact C-N 3.26Å; F326-L328 PolarHBondContact O-N 3.01Å; L328-I335 PolarHBondContact O-N 3.14Å; L328-A336 HydrophobicContact CB-CB 4.21Å; L328-A336 HydrophobicContact CD2-CB 4.31Å; L328-A336 PolarHBondContact N-O 2.98Å; L328-A336 PolarHBondContact O-N 3.05Å; L328-I339 HydrophobicContact CD2-CD1 3.83Å; L328-F458 HydrophobicContact CD1-CD1 4.07Å; L328-F458 HydrophobicContact CD1-CE1 3.64Å; L328-V464 HydrophobicContact CD2-CG2 3.75Å
329R97.8Very high97.6Very high16 Ų1614.8 Ų14.86%0.069%0.085CC..EExtended strand (participates in β ladder)trans-124.8152.8179.6-47.1-178.3-177.1-144.76.4111.9D85 W311 S312 D327 E333 R334D85-R329 IonicContact OD1-NH2 3.61Å; D85-R329 PolarHBondContact OD1-NH2 3.4Å; W311-R329 WeakPolarHBondContact CA-O 3.2Å; S312-R329 PolarHBondContact N-O 2.97Å; S312-R329 VanDerWaalsContact N-O 3.11Å; S312-R329 PolarHBondContact O-N 3.19Å; D327-R329 VanDerWaalsContact CG-NE 3.33Å; D327-R329 WeakPolarHBondContact O-CG 3.23Å; D327-R329 PolarHBondContact O-N 2.76Å; D327-R329 IonicContact OD1-CZ 3.03Å; D327-R329 IonicContact OD1-NE 3.99Å; D327-R329 PolarHBondContact OD1-NE 2.9Å; D327-R329 VanDerWaalsContact OD1-NE 3.07Å; D327-R329 IonicContact OD1-NH2 2.71Å; D327-R329 PolarHBondContact OD1-NH2 2.86Å; D327-R329 IonicContact OD2-CZ 3.4Å; D327-R329 IonicContact OD2-NE 3.04Å; D327-R329 PolarHBondContact OD2-NE 3.16Å; D327-R329 IonicContact OD2-NH2 2.9Å; D327-R329 PolarHBondContact OD2-NH2 3.37Å; R329-E333 CarbonylContact C-O 3.53Å; R329-E333 WeakPolarHBondContact CA-O 3.23Å; R329-E333 WeakPolarHBondContact CB-O 3.38Å; R329-R334 HydrophobicContact CG-CB 4.29Å
330F97.4Very high97.6Very high4 Ų414.6 Ų14.62%0.0188%0.084CC..EExtended strand (participates in β ladder)trans-126.5123.6167-167.2-84.4000109.9G310 W311 G332 E333 I335 P460 F692 P696G310-F330 CarbonylContact O-C 3.57Å; G310-F330 VanDerWaalsContact O-CA 3.26Å; G310-F330 WeakPolarHBondContact O-CA 3.43Å; W311-F330 AromaticContact CD2-CD2 3.64Å; W311-F330 HydrophobicContact CD2-CD2 3.64Å; W311-F330 HydrophobicContact CD2-CE2 4.28Å; W311-F330 AromaticContact CE2-CD2 3.5Å; W311-F330 AromaticContact CE2-CE2 3.83Å; W311-F330 HydrophobicContact CE3-CB 4.28Å; W311-F330 AromaticContact CE3-CD2 3.93Å; W311-F330 HydrophobicContact CE3-CD2 3.93Å; W311-F330 HydrophobicContact CG-CD2 4.16Å; W311-F330 AromaticContact CH2-CD2 3.98Å; W311-F330 HydrophobicContact CH2-CD2 3.98Å; W311-F330 AromaticContact CZ2-CD2 3.72Å; W311-F330 HydrophobicContact CZ2-CD2 3.72Å; W311-F330 HydrophobicContact CZ2-CE2 4.15Å; W311-F330 HydrophobicContact CZ3-CB 4.14Å; W311-F330 HydrophobicContact CZ3-CD2 4.09Å; W311-F330 AromaticContact NE1-CD2 3.89Å; W311-F330 AromaticContact NE1-CE2 3.77Å; F330-G332 PolarHBondContact O-N 3.04Å; F330-E333 PolarHBondContact N-O 2.96Å; F330-E333 PolarHBondContact O-N 2.68Å; F330-E333 VanDerWaalsContact O-N 3.11Å; F330-I335 HydrophobicContact CB-CD1 3.56Å; F330-P460 WeakPolarHBondContact CZ-O 2.95Å; F330-F692 HydrophobicContact CB-CZ 4.32Å; F330-F692 AromaticContact CD1-CE1 3.77Å; F330-F692 HydrophobicContact CD1-CE1 3.77Å; F330-F692 HydrophobicContact CD1-CE2 4.41Å; F330-F692 AromaticContact CD1-CZ 3.42Å; F330-F692 HydrophobicContact CD1-CZ 3.42Å; F330-F692 VanDerWaalsContact CD1-CZ 3.42Å; F330-F692 HydrophobicContact CE1-CE1 4.28Å; F330-F692 AromaticContact CE1-CZ 3.99Å; F330-F692 HydrophobicContact CE1-CZ 3.99Å; F330-F692 HydrophobicContact CG-CZ 4.07Å; F330-P696 HydrophobicContact CE1-CB 3.56Å; F330-P696 HydrophobicContact CE1-CG 4.07Å; F330-P696 HydrophobicContact CZ-CB 3.99Å; F330-P696 HydrophobicContact CZ-CG 4.25Å
331N94.6Very high97.6Very high102 Ų10214.5 Ų14.555%0.5458%0.083SC..THydrogen-bonded Turntrans5038.4-173.1-66.6-18.6000112.9G310 E333G310-N331 WeakPolarHBondContact CA-OD1 3.46Å; G310-N331 PolarHBondContact O-N 3.33Å; N331-E333 VanDerWaalsContact C-N 3.29Å; N331-E333 PolarHBondContact O-N 3.32Å
332G92.6Very high97.7Very high48 Ų4814.6 Ų14.650%0.4958%0.083SC..THydrogen-bonded Turntrans82.9-12.3179.300000115.8F330F330-G332 PolarHBondContact O-N 3.04Å
333E94.5Very high97.7Very high71 Ų7114.6 Ų14.633%0.3328%0.083SC..EExtended strand (participates in β ladder)trans-85.2127.1173.7-66.3-170.7-15700110.3R329 F330 N331 K581 F691R329-E333 CarbonylContact C-O 3.53Å; R329-E333 WeakPolarHBondContact CA-O 3.23Å; R329-E333 WeakPolarHBondContact CB-O 3.38Å; F330-E333 PolarHBondContact N-O 2.96Å; F330-E333 PolarHBondContact O-N 2.68Å; F330-E333 VanDerWaalsContact O-N 3.11Å; N331-E333 VanDerWaalsContact C-N 3.29Å; N331-E333 PolarHBondContact O-N 3.32Å; E333-K581 IonicContact OE1-NZ 3.79Å; E333-K581 PolarHBondContact OE1-NZ 3.01Å; E333-K581 IonicContact OE2-NZ 3.85Å; E333-K581 PolarHBondContact OE2-NZ 3.38Å; E333-F691 HydrophobicContact CB-CE1 4.36Å; E333-F691 HydrophobicContact CB-CZ 4.04Å; E333-F691 WeakPolarHBondContact OE2-CZ 3.23Å
334R96.3Very high97.7Very high19 Ų1914.5 Ų14.57%0.0728%0.083CC..EExtended strand (participates in β ladder)trans-69.5138.2175.6-174.7-178.7-64.1116.13.3111.1L81 D85 D327 R329 D510 V512L81-R334 VanDerWaalsContact CD2-CZ 3.49Å; D85-R334 IonicContact OD1-CZ 2.74Å; D85-R334 IonicContact OD1-NH1 2.8Å; D85-R334 PolarHBondContact OD1-NH1 3.11Å; D85-R334 IonicContact OD1-NH2 3.97Å; D85-R334 PolarHBondContact OD1-NH2 3.45Å; D85-R334 IonicContact OD2-CZ 2.68Å; D85-R334 IonicContact OD2-NH1 2.88Å; D85-R334 PolarHBondContact OD2-NH1 3.16Å; D85-R334 IonicContact OD2-NH2 3.18Å; D85-R334 PolarHBondContact OD2-NH2 2.87Å; D327-R334 IonicContact OD1-CZ 3.32Å; D327-R334 IonicContact OD1-NE 3.25Å; D327-R334 PolarHBondContact OD1-NE 2.89Å; D327-R334 IonicContact OD1-NH2 2.82Å; D327-R334 PolarHBondContact OD1-NH2 3.2Å; D327-R334 IonicContact OD2-NH2 2.75Å; R329-R334 HydrophobicContact CG-CB 4.29Å; R334-D510 HydrophobicContact CG-CB 4.17Å; R334-D510 VanDerWaalsContact O-O 3.07Å; R334-V512 PolarHBondContact O-N 2.88Å
335I98.3Very high97.7Very high1 Ų114.4 Ų14.41%0.0058%0.082CC..EExtended strand (participates in β ladder)trans-112.3-46.6175.7-62.5158.9000109.9W311 L328 F330 D510 I511 Y583 F691W311-I335 HydrophobicContact CH2-CD1 4.11Å; W311-I335 HydrophobicContact CZ3-CD1 3.72Å; L328-I335 PolarHBondContact O-N 3.14Å; F330-I335 HydrophobicContact CB-CD1 3.56Å; I335-D510 CarbonylContact O-C 3.41Å; I335-D510 PolarHBondContact O-N 2.76Å; I335-I511 HydrophobicContact CG2-CD1 4.23Å; I335-I511 WeakPolarHBondContact O-CD1 3.45Å; I335-Y583 HydrophobicContact CB-CE2 4.45Å; I335-Y583 HydrophobicContact CD1-CE1 4.26Å; I335-Y583 HydrophobicContact CD1-CE2 4.08Å; I335-Y583 WeakPolarHBondContact CD1-OH 3.5Å; I335-Y583 HydrophobicContact CG1-CE2 3.78Å; I335-Y583 HydrophobicContact CG2-CD1 3.9Å; I335-Y583 HydrophobicContact CG2-CD2 3.94Å; I335-Y583 HydrophobicContact CG2-CE1 3.83Å; I335-Y583 HydrophobicContact CG2-CE2 3.86Å; I335-Y583 HydrophobicContact CG2-CG 3.96Å; I335-F691 HydrophobicContact CG1-CZ 4.45Å
336A98.7Very high97.6Very high0 Ų014.4 Ų14.40%08%0.083CC..EExtended strand (participates in β ladder)trans-136.4138.5179.600000110.1L328 I339 D508 L509L328-A336 HydrophobicContact CB-CB 4.21Å; L328-A336 HydrophobicContact CD2-CB 4.31Å; L328-A336 PolarHBondContact N-O 2.98Å; L328-A336 PolarHBondContact O-N 3.05Å; A336-I339 HydrophobicContact CB-CD1 4.08Å; A336-I339 HydrophobicContact CB-CG1 3.85Å; A336-D508 CarbonylContact C-O 3.46Å; A336-D508 VanDerWaalsContact CA-O 3.24Å; A336-D508 WeakPolarHBondContact CA-O 3.32Å; A336-D508 WeakPolarHBondContact CB-O 3.37Å; A336-L509 HydrophobicContact CB-CD2 4.07Å
337Y98.7Very high97.6Very high8 Ų814.9 Ų14.93%0.0318%0.084CC..EExtended strand (participates in β ladder)trans-75.8-41.4169.4174.7-100.6000110.9F31 K77 A80 L81 F326 D327 D508F31-Y337 HydrophobicContact CE1-CE2 4.39Å; F31-Y337 HydrophobicContact CZ-CE2 4.1Å; K77-Y337 HydrophobicContact CB-CE1 4.03Å; K77-Y337 HydrophobicContact CD-CD1 3.78Å; K77-Y337 HydrophobicContact CD-CD2 4.46Å; K77-Y337 HydrophobicContact CD-CE1 4.1Å; K77-Y337 HydrophobicContact CD-CG 3.98Å; K77-Y337 HydrophobicContact CG-CD1 3.92Å; K77-Y337 HydrophobicContact CG-CD2 4.06Å; K77-Y337 HydrophobicContact CG-CE1 3.79Å; K77-Y337 HydrophobicContact CG-CE2 3.93Å; K77-Y337 HydrophobicContact CG-CG 4.05Å; A80-Y337 HydrophobicContact CB-CE2 4.15Å; A80-Y337 WeakPolarHBondContact CB-OH 3.2Å; L81-Y337 HydrophobicContact CD2-CD2 3.99Å; L81-Y337 HydrophobicContact CD2-CE2 4.3Å; L81-Y337 HydrophobicContact CG-CD2 4.41Å; L81-Y337 HydrophobicContact CG-CE2 4.41Å; F326-Y337 CarbonylContact C-O 3.41Å; F326-Y337 VanDerWaalsContact CA-O 3.26Å; F326-Y337 WeakPolarHBondContact CA-O 3.49Å; D327-Y337 PolarHBondContact N-O 2.86Å; Y337-D508 WeakPolarHBondContact CD1-OD2 3.33Å; Y337-D508 PolarHBondContact N-O 2.88Å
338E98.9Very high97.6Very high10 Ų1015 Ų155%0.0478%0.084CC..EExtended strand (participates in β ladder)trans-146.9134.3-178179.2-177.4172.800110.4V325 F326 S340 K506 D508V325-E338 CarbonylContact O-C 3.06Å; V325-E338 WeakPolarHBondContact O-CA 3.42Å; F326-E338 HydrophobicContact CD1-CB 4.02Å; F326-E338 HydrophobicContact CD1-CG 4.12Å; F326-E338 HydrophobicContact CE1-CB 3.82Å; F326-E338 HydrophobicContact CE1-CG 3.51Å; F326-E338 HydrophobicContact CZ-CG 3.86Å; E338-S340 VanDerWaalsContact OE1-CB 3.28Å; E338-S340 WeakPolarHBondContact OE1-CB 3.4Å; E338-S340 PolarHBondContact OE1-OG 3.07Å; E338-K506 IonicContact OE1-NZ 3.26Å; E338-K506 WeakPolarHBondContact OE2-CE 3.36Å; E338-K506 IonicContact OE2-NZ 3.83Å; E338-K506 PolarHBondContact OE2-NZ 2.9Å; E338-D508 HydrophobicContact CB-CB 4.02Å; E338-D508 PolarHBondContact O-N 2.79Å
339I98.9Very high97.6Very high1 Ų116.4 Ų16.41%0.00510%0.096CC..EExtended strand (participates in β ladder)trans-126.9117.6160.4-47172.9000107.3Q324 V325 L328 A336 F456 V466 K506 V507 F684 L686Q324-I339 WeakPolarHBondContact CA-O 2.93Å; V325-I339 PolarHBondContact N-O 2.9Å; V325-I339 PolarHBondContact O-N 2.94Å; L328-I339 HydrophobicContact CD2-CD1 3.83Å; A336-I339 HydrophobicContact CB-CD1 4.08Å; A336-I339 HydrophobicContact CB-CG1 3.85Å; I339-F456 HydrophobicContact CB-CE1 3.83Å; I339-F456 HydrophobicContact CB-CZ 4.18Å; I339-F456 HydrophobicContact CD1-CE1 4.48Å; I339-F456 HydrophobicContact CG2-CE1 3.58Å; I339-F456 HydrophobicContact CG2-CZ 3.95Å; I339-V466 HydrophobicContact CG2-CG2 4.13Å; I339-K506 CarbonylContact C-O 3.12Å; I339-K506 VanDerWaalsContact CA-O 3.31Å; I339-K506 WeakPolarHBondContact CA-O 3.4Å; I339-V507 HydrophobicContact CG1-CG1 4.26Å; I339-V507 HydrophobicContact CG2-CG2 4.28Å; I339-F684 HydrophobicContact CG2-CZ 4.24Å; I339-L686 HydrophobicContact CD1-CD1 3.49Å; I339-L686 VanDerWaalsContact CD1-CD1 3.49Å; I339-L686 HydrophobicContact CG1-CD1 4.45Å
340S98.8Very high97.6Very high0 Ų015.9 Ų15.90%010%0.095CC..EExtended strand (participates in β ladder)trans-142.2139.4-170.657.20000113.6Q324 E338 Q342 Y505 K506Q324-S340 VanDerWaalsContact CG-CB 3.49Å; E338-S340 VanDerWaalsContact OE1-CB 3.28Å; E338-S340 WeakPolarHBondContact OE1-CB 3.4Å; E338-S340 PolarHBondContact OE1-OG 3.07Å; S340-Q342 PolarHBondContact OG-NE2 3.2Å; S340-Y505 WeakPolarHBondContact O-CA 3.45Å; S340-K506 PolarHBondContact N-O 3.15Å; S340-K506 PolarHBondContact O-N 3.37Å
341L98.9Very high97.6Very high1 Ų117.2 Ų17.21%0.00510%0.103CC..EExtended strand (participates in β ladder)trans-62.6132.8165.3178.760.6000109.3A321 L323 M367 W454 I503 Y505A321-L341 WeakPolarHBondContact O-CD2 3.28Å; L323-L341 PolarHBondContact O-N 2.89Å; L341-M367 HydrophobicContact CD2-SD 3.98Å; L341-W454 HydrophobicContact CD1-CE3 4.39Å; L341-W454 HydrophobicContact CD1-CH2 4.07Å; L341-W454 HydrophobicContact CD1-CZ3 3.87Å; L341-W454 HydrophobicContact CD2-CD2 3.85Å; L341-W454 HydrophobicContact CD2-CE3 3.97Å; L341-W454 HydrophobicContact CD2-CH2 3.88Å; L341-W454 HydrophobicContact CD2-CZ2 3.72Å; L341-W454 HydrophobicContact CD2-CZ3 3.98Å; L341-I503 HydrophobicContact CD1-CG2 3.52Å; L341-Y505 HydrophobicContact CB-CD1 4.46Å; L341-Y505 HydrophobicContact CB-CE1 4.17Å; L341-Y505 HydrophobicContact CD1-CE1 4.08Å
342Q98.8Very high97.8Very high4 Ų412.4 Ų12.42%0.0198%0.077CC..EExtended strand (participates in β ladder)trans-112.4-41.7-178-64.5-66.1-49.600112.8S340 H504 K506 S624 W658S340-Q342 PolarHBondContact OG-NE2 3.2Å; Q342-H504 HydrophobicContact CB-CB 4.27Å; Q342-H504 WeakPolarHBondContact CB-O 3.42Å; Q342-H504 PolarHBondContact N-O 2.89Å; Q342-K506 HydrophobicContact CG-CB 3.78Å; Q342-S624 VanDerWaalsContact CB-OG 3.25Å; Q342-S624 WeakPolarHBondContact CB-OG 3.41Å; Q342-W658 HydrophobicContact CG-CZ3 4.18Å
343E98.7Very high98Very high0 Ų010.2 Ų10.20%05%0.054CC..EExtended strand (participates in β ladder)trans-162.5154.6-178-170.356.2-84.600111I345 I361 D362 A363 M367 I503 H504 W607 S625E343-I345 HydrophobicContact CG-CG2 3.97Å; E343-I361 VanDerWaalsContact CD-CG2 3.4Å; E343-I361 HydrophobicContact CG-CG2 4.06Å; E343-I361 WeakPolarHBondContact OE2-CG2 3.41Å; E343-D362 PolarHBondContact OE1-N 2.96Å; E343-A363 WeakPolarHBondContact OE1-CB 3.3Å; E343-A363 PolarHBondContact OE1-N 3.15Å; E343-A363 WeakPolarHBondContact OE2-CB 3.5Å; E343-M367 WeakPolarHBondContact OE1-CE 3.32Å; E343-I503 WeakPolarHBondContact O-CA 3.24Å; E343-H504 HydrophobicContact CB-CB 4.38Å; E343-H504 PolarHBondContact N-O 3.01Å; E343-H504 PolarHBondContact O-N 3.36Å; E343-W607 HydrophobicContact CB-CH2 4.45Å; E343-W607 HydrophobicContact CB-CZ2 3.84Å; E343-W607 HydrophobicContact CG-CH2 4.28Å; E343-W607 HydrophobicContact CG-CZ2 3.51Å; E343-S625 WeakPolarHBondContact OE2-CB 3.12Å; E343-S625 PolarHBondContact OE2-OG 2.8Å
344A98.6Very high98.2Very high0 Ų06.8 Ų6.80%04%0.038CC..EExtended strand (participates in β ladder)trans-132.8137.7165.800000108.4D362 M367 W454 L502 I503A344-D362 HydrophobicContact CB-CB 4.31Å; A344-D362 PolarHBondContact O-N 3.08Å; A344-M367 HydrophobicContact CB-CE 3.93Å; A344-M367 HydrophobicContact CB-SD 4.08Å; A344-W454 HydrophobicContact CB-CH2 4Å; A344-W454 HydrophobicContact CB-CZ2 4.46Å; A344-L502 CarbonylContact C-O 3.49Å; A344-L502 WeakPolarHBondContact CA-O 3.42Å; A344-I503 HydrophobicContact CB-CG1 4.32Å
345I98.2Very high98.3Very high1 Ų15.9 Ų5.91%0.0054%0.035CC..EExtended strand (participates in β ladder)trans-128.8148.7177.274.4177.5000110.7E343 F347 Y360 I361 H501 L502 V594 I605 W607E343-I345 HydrophobicContact CG-CG2 3.97Å; I345-F347 HydrophobicContact CB-CD1 3.76Å; I345-F347 HydrophobicContact CB-CE1 3.67Å; I345-F347 HydrophobicContact CD1-CD1 3.75Å; I345-F347 HydrophobicContact CD1-CE1 3.75Å; I345-F347 HydrophobicContact CD1-CG 4.21Å; I345-F347 HydrophobicContact CD1-CZ 4.19Å; I345-F347 HydrophobicContact CG1-CD1 3.94Å; I345-F347 HydrophobicContact CG1-CE1 4.12Å; I345-F347 HydrophobicContact CG2-CE1 4.07Å; I345-Y360 WeakPolarHBondContact CA-O 3.36Å; I345-Y360 WeakPolarHBondContact CB-O 3.42Å; I345-I361 HydrophobicContact CG2-CB 4.49Å; I345-I361 HydrophobicContact CG2-CG1 4.15Å; I345-I361 HydrophobicContact CG2-CG2 4.5Å; I345-H501 WeakPolarHBondContact O-CA 3.37Å; I345-L502 HydrophobicContact CD1-CB 3.85Å; I345-L502 HydrophobicContact CD1-CD1 4Å; I345-L502 HydrophobicContact CD1-CG 4.19Å; I345-L502 HydrophobicContact CG1-CB 3.72Å; I345-L502 HydrophobicContact CG1-CG 4.4Å; I345-L502 PolarHBondContact N-O 3.41Å; I345-L502 PolarHBondContact O-N 2.83Å; I345-L502 VanDerWaalsContact O-N 3.14Å; I345-V594 HydrophobicContact CD1-CG1 4.24Å; I345-I605 HydrophobicContact CD1-CD1 3.92Å; I345-I605 HydrophobicContact CG2-CG2 4.23Å; I345-W607 HydrophobicContact CB-CH2 4.45Å; I345-W607 HydrophobicContact CD1-CH2 3.91Å; I345-W607 HydrophobicContact CD1-CZ2 4.43Å; I345-W607 HydrophobicContact CG1-CH2 4.04Å; I345-W607 HydrophobicContact CG2-CH2 3.66Å; I345-W607 HydrophobicContact CG2-CZ2 3.55Å
346A97.8Very high98.2Very high2 Ų210 Ų102%0.0176%0.055CC..EExtended strand (participates in β ladder)trans-130.3107.1166.800000108.5Y348 Y360 T500A346-Y348 HydrophobicContact CB-CE2 3.6Å; A346-Y348 WeakPolarHBondContact O-CD2 3.38Å; A346-Y348 WeakPolarHBondContact O-CE2 3.33Å; A346-Y360 PolarHBondContact N-O 3.11Å; A346-Y360 VanDerWaalsContact N-O 3.12Å; A346-Y360 PolarHBondContact O-N 3Å; A346-T500 WeakPolarHBondContact CA-O 3.36Å
347F97.3Very high98.2Very high10 Ų1011 Ų114%0.0446%0.06CC..EExtended strand (participates in β ladder)trans-108.4113.7-173.2-88.139.4000109.5I345 K359 Y360 I361 H499 T500 V594 L595 I605I345-F347 HydrophobicContact CB-CD1 3.76Å; I345-F347 HydrophobicContact CB-CE1 3.67Å; I345-F347 HydrophobicContact CD1-CD1 3.75Å; I345-F347 HydrophobicContact CD1-CE1 3.75Å; I345-F347 HydrophobicContact CD1-CG 4.21Å; I345-F347 HydrophobicContact CD1-CZ 4.19Å; I345-F347 HydrophobicContact CG1-CD1 3.94Å; I345-F347 HydrophobicContact CG1-CE1 4.12Å; I345-F347 HydrophobicContact CG2-CE1 4.07Å; F347-K359 HydrophobicContact CD1-CB 3.94Å; F347-K359 HydrophobicContact CD2-CB 4.11Å; F347-K359 HydrophobicContact CD2-CG 3.96Å; F347-K359 HydrophobicContact CE1-CB 3.75Å; F347-K359 HydrophobicContact CE2-CB 3.94Å; F347-K359 HydrophobicContact CE2-CD 4.41Å; F347-K359 HydrophobicContact CE2-CG 4.05Å; F347-K359 HydrophobicContact CG-CB 4.11Å; F347-K359 HydrophobicContact CG-CG 4.21Å; F347-K359 HydrophobicContact CZ-CB 3.75Å; F347-K359 HydrophobicContact CZ-CG 4.38Å; F347-Y360 WeakPolarHBondContact CE1-O 3.25Å; F347-I361 HydrophobicContact CE1-CG1 3.99Å; F347-I361 HydrophobicContact CZ-CD1 4.47Å; F347-I361 HydrophobicContact CZ-CG1 4.33Å; F347-H499 CarbonylContact O-C 3.57Å; F347-H499 WeakPolarHBondContact O-CA 3.36Å; F347-H499 VanDerWaalsContact O-CB 3.24Å; F347-H499 WeakPolarHBondContact O-CB 3.17Å; F347-T500 PolarHBondContact N-O 3.04Å; F347-T500 VanDerWaalsContact N-O 3.12Å; F347-T500 PolarHBondContact O-N 2.92Å; F347-V594 HydrophobicContact CB-CG2 3.59Å; F347-V594 HydrophobicContact CD2-CG1 3.97Å; F347-V594 HydrophobicContact CD2-CG2 3.96Å; F347-V594 HydrophobicContact CE2-CG1 4.4Å; F347-V594 HydrophobicContact CG-CG1 4.5Å; F347-V594 HydrophobicContact CG-CG2 4.11Å; F347-L595 HydrophobicContact CD2-CD1 4.05Å; F347-L595 HydrophobicContact CD2-CG 3.99Å; F347-L595 HydrophobicContact CE2-CD1 3.57Å; F347-L595 HydrophobicContact CE2-CG 3.98Å; F347-I605 HydrophobicContact CD2-CD1 4.21Å; F347-I605 HydrophobicContact CE1-CD1 4.34Å; F347-I605 HydrophobicContact CE2-CD1 3.33Å; F347-I605 HydrophobicContact CE2-CG1 4.31Å; F347-I605 HydrophobicContact CZ-CD1 3.42Å; F347-I605 VanDerWaalsContact CZ-CD1 3.42Å; F347-I605 HydrophobicContact CZ-CG1 4.14Å; F347-I605 HydrophobicContact CZ-CG2 4.14Å
348Y98.2Very high98.2Very high16 Ų1610.7 Ų10.76%0.0636%0.058CC..EExtended strand (participates in β ladder)trans-97.8161.4-171-66.3-97.4000112.6A346 T358 Y360 Y450 H475 N497 L498 H499A346-Y348 HydrophobicContact CB-CE2 3.6Å; A346-Y348 WeakPolarHBondContact O-CD2 3.38Å; A346-Y348 WeakPolarHBondContact O-CE2 3.33Å; Y348-T358 HydrophobicContact CD2-CG2 3.38Å; Y348-T358 HydrophobicContact CE2-CG2 3.94Å; Y348-T358 HydrophobicContact CG-CG2 4.1Å; Y348-T358 PolarHBondContact N-O 3.31Å; Y348-Y360 HydrophobicContact CD2-CD2 4.45Å; Y348-Y360 AromaticContact CE2-CD2 3.86Å; Y348-Y360 HydrophobicContact CE2-CD2 3.86Å; Y348-Y360 HydrophobicContact CE2-CE2 4.25Å; Y348-Y450 WeakPolarHBondContact OH-CE2 3.41Å; Y348-H475 HydrophobicContact CD1-CB 4.46Å; Y348-H475 AromaticContact CD1-CD2 3.83Å; Y348-H475 HydrophobicContact CE1-CB 3.64Å; Y348-H475 AromaticContact CE1-CD2 3.87Å; Y348-H475 HydrophobicContact CE2-CB 4.4Å; Y348-N497 HydrophobicContact CD1-CB 3.81Å; Y348-L498 CarbonylContact C-O 3.45Å; Y348-L498 WeakPolarHBondContact CA-O 3.24Å; Y348-H499 HydrophobicContact CD1-CB 3.44Å; Y348-H499 VanDerWaalsContact CD1-CB 3.44Å; Y348-H499 AromaticContact CD1-CG 3.75Å; Y348-H499 AromaticContact CD1-ND1 3.84Å; Y348-H499 HydrophobicContact CD2-CB 4.17Å; Y348-H499 HydrophobicContact CE1-CB 3.54Å; Y348-H499 AromaticContact CE1-CD2 3.93Å; Y348-H499 AromaticContact CE1-CE1 3.94Å; Y348-H499 AromaticContact CE1-CG 3.31Å; Y348-H499 AromaticContact CE1-ND1 3.32Å; Y348-H499 VanDerWaalsContact CE1-ND1 3.32Å; Y348-H499 WeakPolarHBondContact CE1-ND1 3.43Å; Y348-H499 HydrophobicContact CE2-CB 4.28Å; Y348-H499 HydrophobicContact CG-CB 3.74Å; Y348-H499 AromaticContact CZ-CD2 3.91Å; Y348-H499 AromaticContact CZ-CG 3.71Å
349A97.3Very high98.1Very high30 Ų3011.3 Ų11.325%0.2486%0.061CC..  trans-125.6153.7160.400000109.4Y486 N497 L498A349-Y486 HydrophobicContact CB-CD1 3.96Å; A349-N497 PolarHBondContact O-ND2 2.88Å; A349-L498 PolarHBondContact N-O 2.74Å
350G97.5Very high98.1Very high5 Ų512 Ų125%0.0526%0.063CC..  trans-171.3167.817800000113
351D97.9Very high98.1Very high33 Ų3312 Ų1218%0.1766%0.064CC..SBendtrans-84.3-29.8173.1-174.462.8000111.8M356 T480 N482 Y486D351-M356 WeakPolarHBondContact O-CE 3.2Å; D351-T480 PolarHBondContact OD2-OG1 3.3Å; D351-N482 HydrophobicContact CB-CB 4.41Å; D351-N482 VanDerWaalsContact OD1-CB 3.25Å; D351-N482 WeakPolarHBondContact OD1-CB 3.21Å; D351-Y486 HydrophobicContact CB-CD2 4.07Å; D351-Y486 HydrophobicContact CB-CE2 4.33Å
352T98.5Very high98.1Very high0 Ų012.4 Ų12.40%07%0.066CC..SBendtrans-78.7150.2177.683.60000111.5E217 W236 A354 A355 M356E217-T352 WeakPolarHBondContact OE1-CB 3.3Å; E217-T352 PolarHBondContact OE1-OG1 2.78Å; W236-T352 HydrophobicContact CH2-CG2 3.53Å; W236-T352 HydrophobicContact CZ2-CG2 3.84Å; W236-T352 HydrophobicContact CZ3-CG2 4.03Å; T352-A354 VanDerWaalsContact C-N 3.26Å; T352-A354 PolarHBondContact O-N 3.14Å; T352-A355 PolarHBondContact O-N 2.9Å; T352-A355 PolarHBondContact OG1-N 3.19Å; T352-M356 WeakPolarHBondContact O-CG 3.26Å; T352-M356 PolarHBondContact O-N 2.77Å
353P98.4Very high98Very high2 Ų212.4 Ų12.41%0.0137%0.066CC..Hα-helixtrans-54.1-41.5177.8-17.221.1000113.2W199 E217 W236 Y241 M356 Q357W199-P353 HydrophobicContact CD2-CB 3.56Å; W199-P353 HydrophobicContact CD2-CG 4.48Å; W199-P353 HydrophobicContact CE3-CB 3.89Å; W199-P353 HydrophobicContact CE3-CG 4.36Å; W199-P353 HydrophobicContact CG-CB 4.19Å; W199-P353 HydrophobicContact CH2-CB 3.68Å; W199-P353 HydrophobicContact CH2-CG 3.71Å; W199-P353 HydrophobicContact CZ2-CB 3.33Å; W199-P353 HydrophobicContact CZ2-CG 3.83Å; W199-P353 HydrophobicContact CZ3-CB 3.94Å; W199-P353 HydrophobicContact CZ3-CG 3.99Å; E217-P353 VanDerWaalsContact OE2-CD 3.26Å; E217-P353 WeakPolarHBondContact OE2-CD 3.42Å; W236-P353 HydrophobicContact CB-CG 3.7Å; W236-P353 HydrophobicContact CD2-CG 4.32Å; W236-P353 HydrophobicContact CG-CG 3.61Å; Y241-P353 HydrophobicContact CE1-CB 4.4Å; Y241-P353 HydrophobicContact CE1-CG 3.59Å; Y241-P353 WeakPolarHBondContact OH-CG 3.41Å; P353-M356 WeakPolarHBondContact O-CG 3.36Å; P353-Q357 VanDerWaalsContact O-CB 3.26Å; P353-Q357 WeakPolarHBondContact O-CB 3.43Å; P353-Q357 PolarHBondContact O-N 3.18Å
354A97.9Very high98Very high0 Ų012.5 Ų12.50%07%0.067CC..Hα-helixtrans-55.6-61.6174.700000110.4I186 W199 M201 E217 T352 M356 Q357 T358I186-A354 HydrophobicContact CD1-CB 4.1Å; I186-A354 HydrophobicContact CG1-CB 3.66Å; W199-A354 HydrophobicContact CB-CB 4.47Å; M201-A354 HydrophobicContact CB-CB 4.44Å; M201-A354 HydrophobicContact SD-CB 4.46Å; E217-A354 VanDerWaalsContact CD-CB 3.43Å; E217-A354 HydrophobicContact CG-CB 4.5Å; E217-A354 WeakPolarHBondContact OE1-CB 3.32Å; E217-A354 WeakPolarHBondContact OE2-CB 3.42Å; E217-A354 PolarHBondContact OE2-N 2.75Å; T352-A354 VanDerWaalsContact C-N 3.26Å; T352-A354 PolarHBondContact O-N 3.14Å; A354-M356 PolarHBondContact O-N 2.67Å; A354-Q357 WeakPolarHBondContact O-CB 3.46Å; A354-Q357 PolarHBondContact O-N 2.86Å; A354-T358 PolarHBondContact O-N 2.95Å; A354-T358 PolarHBondContact O-OG1 2.61Å
355A97.6Very high97.9Very high0 Ų015 Ų150%08%0.077CC..Hα-helixtrans-63.7-36.1-173.500000114.5T352 Q357 T358 T477 N497T352-A355 PolarHBondContact O-N 2.9Å; T352-A355 PolarHBondContact OG1-N 3.19Å; A355-Q357 PolarHBondContact O-N 3.39Å; A355-T358 PolarHBondContact O-N 2.85Å; A355-T477 HydrophobicContact CB-CG2 3.6Å; A355-N497 WeakPolarHBondContact CB-ND2 3.18Å
356M97.4Very high97.9Very high87 Ų8715 Ų1543%0.4298%0.077SC..Hα-helixtrans-70.2-25.417772176.871.500112.7D351 T352 P353 A354 K359D351-M356 WeakPolarHBondContact O-CE 3.2Å; T352-M356 WeakPolarHBondContact O-CG 3.26Å; T352-M356 PolarHBondContact O-N 2.77Å; P353-M356 WeakPolarHBondContact O-CG 3.36Å; A354-M356 PolarHBondContact O-N 2.67Å; M356-K359 PolarHBondContact O-NZ 2.96Å
357Q98.1Very high97.9Very high22 Ų2214.9 Ų14.910%0.1038%0.076CC..Hα-helixtrans-80.6-34.1175.9-173.163.819.300111.6I186 P188 G190 P353 A354 A355 K359I186-Q357 HydrophobicContact CG2-CB 4.07Å; I186-Q357 HydrophobicContact CG2-CG 4.18Å; P188-Q357 PolarHBondContact O-NE2 3.42Å; G190-Q357 PolarHBondContact O-NE2 3.24Å; P353-Q357 VanDerWaalsContact O-CB 3.26Å; P353-Q357 WeakPolarHBondContact O-CB 3.43Å; P353-Q357 PolarHBondContact O-N 3.18Å; A354-Q357 WeakPolarHBondContact O-CB 3.46Å; A354-Q357 PolarHBondContact O-N 2.86Å; A355-Q357 PolarHBondContact O-N 3.39Å; Q357-K359 PolarHBondContact O-N 2.72Å; Q357-K359 VanDerWaalsContact O-N 3.12Å; Q357-K359 PolarHBondContact O-NZ 3.46Å
358T98.5Very high98Very high0 Ų014.4 Ų14.40%07%0.074CC..  trans-58109.6-171.3-48.80000114.4I186 A187 Y348 A354 A355 Y360 H475I186-T358 HydrophobicContact CG2-CG2 4.35Å; I186-T358 WeakPolarHBondContact CG2-OG1 3.42Å; A187-T358 WeakPolarHBondContact O-CA 3.47Å; Y348-T358 HydrophobicContact CD2-CG2 3.38Å; Y348-T358 HydrophobicContact CE2-CG2 3.94Å; Y348-T358 HydrophobicContact CG-CG2 4.1Å; Y348-T358 PolarHBondContact N-O 3.31Å; A354-T358 PolarHBondContact O-N 2.95Å; A354-T358 PolarHBondContact O-OG1 2.61Å; A355-T358 PolarHBondContact O-N 2.85Å; T358-Y360 HydrophobicContact CG2-CD1 4.21Å; T358-Y360 HydrophobicContact CG2-CD2 3.5Å; T358-Y360 HydrophobicContact CG2-CE1 3.94Å; T358-Y360 HydrophobicContact CG2-CE2 3.18Å; T358-Y360 HydrophobicContact CG2-CG 4Å; T358-Y360 VanDerWaalsContact CG2-CZ 3.41Å; T358-H475 PolarHBondContact OG1-NE2 3.26Å
359K97.9Very high98Very high23 Ų2314.4 Ų14.410%0.18%0.076CC..EExtended strand (participates in β ladder)trans-136.281.9172.8-61.2157.5-165.770.30107.4A187 F347 M356 Q357 E601 Q630A187-K359 PolarHBondContact O-N 3.13Å; F347-K359 HydrophobicContact CD1-CB 3.94Å; F347-K359 HydrophobicContact CD2-CB 4.11Å; F347-K359 HydrophobicContact CD2-CG 3.96Å; F347-K359 HydrophobicContact CE1-CB 3.75Å; F347-K359 HydrophobicContact CE2-CB 3.94Å; F347-K359 HydrophobicContact CE2-CD 4.41Å; F347-K359 HydrophobicContact CE2-CG 4.05Å; F347-K359 HydrophobicContact CG-CB 4.11Å; F347-K359 HydrophobicContact CG-CG 4.21Å; F347-K359 HydrophobicContact CZ-CB 3.75Å; F347-K359 HydrophobicContact CZ-CG 4.38Å; M356-K359 PolarHBondContact O-NZ 2.96Å; Q357-K359 PolarHBondContact O-N 2.72Å; Q357-K359 VanDerWaalsContact O-N 3.12Å; Q357-K359 PolarHBondContact O-NZ 3.46Å; K359-E601 HydrophobicContact CD-CB 4.25Å; K359-E601 HydrophobicContact CD-CG 4.01Å; K359-Q630 PolarHBondContact O-NE2 3.03Å
360Y98.5Very high98Very high15 Ų1513.4 Ų13.46%0.0597%0.067CC..EExtended strand (participates in β ladder)trans-74.3135.8-176.6-67.8-47.5000111.3D185 I186 A187 I345 A346 F347 Y348 T358D185-Y360 PolarHBondContact O-OH 3Å; I186-Y360 WeakPolarHBondContact CD1-OH 3.24Å; A187-Y360 HydrophobicContact CB-CD1 4.36Å; A187-Y360 HydrophobicContact CB-CE1 4.34Å; I345-Y360 WeakPolarHBondContact CA-O 3.36Å; I345-Y360 WeakPolarHBondContact CB-O 3.42Å; A346-Y360 PolarHBondContact N-O 3.11Å; A346-Y360 VanDerWaalsContact N-O 3.12Å; A346-Y360 PolarHBondContact O-N 3Å; F347-Y360 WeakPolarHBondContact CE1-O 3.25Å; Y348-Y360 HydrophobicContact CD2-CD2 4.45Å; Y348-Y360 AromaticContact CE2-CD2 3.86Å; Y348-Y360 HydrophobicContact CE2-CD2 3.86Å; Y348-Y360 HydrophobicContact CE2-CE2 4.25Å; T358-Y360 HydrophobicContact CG2-CD1 4.21Å; T358-Y360 HydrophobicContact CG2-CD2 3.5Å; T358-Y360 HydrophobicContact CG2-CE1 3.94Å; T358-Y360 HydrophobicContact CG2-CE2 3.18Å; T358-Y360 HydrophobicContact CG2-CG 4Å; T358-Y360 VanDerWaalsContact CG2-CZ 3.41Å
361I98.5Very high98Very high2 Ų213.2 Ų13.21%0.016%0.064CC..EExtended strand (participates in β ladder)trans-131.291.9178.8-57.5177.2000105.1E343 I345 F347 A363 G364 I605 T629 Q630 P633E343-I361 VanDerWaalsContact CD-CG2 3.4Å; E343-I361 HydrophobicContact CG-CG2 4.06Å; E343-I361 WeakPolarHBondContact OE2-CG2 3.41Å; I345-I361 HydrophobicContact CG2-CB 4.49Å; I345-I361 HydrophobicContact CG2-CG1 4.15Å; I345-I361 HydrophobicContact CG2-CG2 4.5Å; F347-I361 HydrophobicContact CE1-CG1 3.99Å; F347-I361 HydrophobicContact CZ-CD1 4.47Å; F347-I361 HydrophobicContact CZ-CG1 4.33Å; I361-A363 VanDerWaalsContact C-N 3.26Å; I361-A363 PolarHBondContact O-N 3.39Å; I361-A363 VanDerWaalsContact O-N 3.16Å; I361-G364 PolarHBondContact O-N 3.39Å; I361-I605 HydrophobicContact CD1-CG2 3.76Å; I361-I605 HydrophobicContact CG1-CG2 4.18Å; I361-T629 HydrophobicContact CD1-CG2 3.99Å; I361-T629 HydrophobicContact CG2-CG2 4.37Å; I361-Q630 HydrophobicContact CB-CB 4.2Å; I361-Q630 PolarHBondContact O-OE1 3.01Å; I361-P633 HydrophobicContact CD1-CB 4.26Å
362D98.6Very high98Very high9 Ų915.1 Ų15.15%0.0487%0.069CC..G310 helixtrans-67.7-22.8-157-69.1-24.5000113.4E343 A344 G364 W365 M367 V447 Y452E343-D362 PolarHBondContact OE1-N 2.96Å; A344-D362 HydrophobicContact CB-CB 4.31Å; A344-D362 PolarHBondContact O-N 3.08Å; D362-G364 PolarHBondContact O-N 2.93Å; D362-G364 VanDerWaalsContact O-N 3.16Å; D362-W365 WeakPolarHBondContact O-CB 3.21Å; D362-W365 PolarHBondContact O-N 3.27Å; D362-M367 HydrophobicContact CB-CB 4.09Å; D362-M367 HydrophobicContact CB-CE 3.53Å; D362-M367 HydrophobicContact CB-SD 4.09Å; D362-M367 PolarHBondContact O-N 3.38Å; D362-V447 HydrophobicContact CB-CG2 4.21Å; D362-Y452 VanDerWaalsContact OD2-CE2 3.26Å; D362-Y452 WeakPolarHBondContact OD2-CE2 2.95Å
363A97.4Very high98Very high3 Ų315.8 Ų15.83%0.0257%0.073CC..G310 helixtrans-61-24.317200000111.9E343 I361 W365 A366 M367 I627E343-A363 WeakPolarHBondContact OE1-CB 3.3Å; E343-A363 PolarHBondContact OE1-N 3.15Å; E343-A363 WeakPolarHBondContact OE2-CB 3.5Å; I361-A363 VanDerWaalsContact C-N 3.26Å; I361-A363 PolarHBondContact O-N 3.39Å; I361-A363 VanDerWaalsContact O-N 3.16Å; A363-W365 PolarHBondContact O-N 3.07Å; A363-A366 WeakPolarHBondContact O-CA 3.36Å; A363-A366 PolarHBondContact O-N 3.39Å; A363-M367 HydrophobicContact CB-CE 4.28Å; A363-I627 WeakPolarHBondContact O-CA 3.47Å; A363-I627 WeakPolarHBondContact O-CB 3.42Å; A363-I627 WeakPolarHBondContact O-CG2 3.28Å
364G97.6Very high98Very high2 Ų215.7 Ų15.72%0.0217%0.072CC..G310 helixtrans-61.3-18.9172.800000114.7P140 I361 D362 I627P140-G364 WeakPolarHBondContact CB-O 3.4Å; P140-G364 WeakPolarHBondContact CG-O 3.26Å; I361-G364 PolarHBondContact O-N 3.39Å; D362-G364 PolarHBondContact O-N 2.93Å; D362-G364 VanDerWaalsContact O-N 3.16Å; G364-I627 WeakPolarHBondContact CA-O 3.43Å
365W97.8Very high98.1Very high54 Ų5416.2 Ų16.221%0.2058%0.076CC..G310 helixtrans-10410175.6-60.988.8000112.5I141 Y146 D362 A363 M367 V447I141-W365 HydrophobicContact CG2-CE3 4.31Å; I141-W365 HydrophobicContact CG2-CH2 4.01Å; I141-W365 HydrophobicContact CG2-CZ3 3.75Å; Y146-W365 HydrophobicContact CE2-CZ3 4.27Å; Y146-W365 WeakPolarHBondContact OH-CH2 3.19Å; Y146-W365 WeakPolarHBondContact OH-CZ3 3.41Å; D362-W365 WeakPolarHBondContact O-CB 3.21Å; D362-W365 PolarHBondContact O-N 3.27Å; A363-W365 PolarHBondContact O-N 3.07Å; W365-M367 PolarHBondContact O-N 3.43Å; W365-V447 HydrophobicContact CB-CG1 3.64Å; W365-V447 HydrophobicContact CG-CG1 3.89Å
366A97.8Very high98Very high0 Ų017.4 Ų17.40%08%0.084CC..THydrogen-bonded Turntrans49.355.9-170.300000111.5S319 A363 G368 T369 F393S319-A366 CarbonylContact O-C 3.54Å; A363-A366 WeakPolarHBondContact O-CA 3.36Å; A363-A366 PolarHBondContact O-N 3.39Å; A366-G368 PolarHBondContact O-N 3.15Å; A366-T369 HydrophobicContact CB-CG2 4.23Å; A366-T369 PolarHBondContact O-N 3.46Å; A366-T369 PolarHBondContact O-OG1 3.37Å; A366-F393 HydrophobicContact CB-CD1 4.03Å; A366-F393 HydrophobicContact CB-CD2 3.81Å; A366-F393 HydrophobicContact CB-CE1 3.96Å; A366-F393 HydrophobicContact CB-CE2 3.73Å; A366-F393 HydrophobicContact CB-CG 3.95Å; A366-F393 HydrophobicContact CB-CZ 3.81Å
367M98.3Very high97.9Very high0 Ų014.3 Ų14.30%08%0.075CC..G310 helixtrans-50.8-23.3-171.885.5177.587.200115.7A321 L341 E343 A344 D362 A363 W365 T369 S370 S445 V447 W454A321-M367 WeakPolarHBondContact O-CG 2.94Å; L341-M367 HydrophobicContact CD2-SD 3.98Å; E343-M367 WeakPolarHBondContact OE1-CE 3.32Å; A344-M367 HydrophobicContact CB-CE 3.93Å; A344-M367 HydrophobicContact CB-SD 4.08Å; D362-M367 HydrophobicContact CB-CB 4.09Å; D362-M367 HydrophobicContact CB-CE 3.53Å; D362-M367 HydrophobicContact CB-SD 4.09Å; D362-M367 PolarHBondContact O-N 3.38Å; A363-M367 HydrophobicContact CB-CE 4.28Å; W365-M367 PolarHBondContact O-N 3.43Å; M367-T369 PolarHBondContact O-N 3.02Å; M367-S370 WeakPolarHBondContact O-CB 3.1Å; M367-S370 PolarHBondContact O-N 3.46Å; M367-S370 VanDerWaalsContact O-N 3.15Å; M367-S445 WeakPolarHBondContact O-CB 3.21Å; M367-S445 PolarHBondContact O-OG 2.96Å; M367-V447 HydrophobicContact CB-CG2 3.66Å; M367-W454 HydrophobicContact SD-CZ2 4.06Å
368G98.1Very high97.8Very high0 Ų019.4 Ų19.40%010%0.101CC..G310 helixtrans-70.7-10.617600000114S319 A366 T371 H391S319-G368 CarbonylContact O-C 3.54Å; S319-G368 WeakPolarHBondContact O-CA 3.46Å; S319-G368 PolarHBondContact O-N 3.04Å; S319-G368 VanDerWaalsContact O-N 3.12Å; A366-G368 PolarHBondContact O-N 3.15Å; G368-T371 WeakPolarHBondContact O-CG2 3.47Å; G368-H391 PolarHBondContact O-CE1 3.19Å; G368-H391 PolarHBondContact O-NE2 3.33Å
369T98Very high97.8Very high16 Ų1621.8 Ų21.810%0.09811%0.114CC..G310 helixtrans-92.2-11.6169.766.90000113S319 A366 M367 T371 H391 F393 H401S319-T369 PolarHBondContact O-N 2.86Å; A366-T369 HydrophobicContact CB-CG2 4.23Å; A366-T369 PolarHBondContact O-N 3.46Å; A366-T369 PolarHBondContact O-OG1 3.37Å; M367-T369 PolarHBondContact O-N 3.02Å; T369-T371 PolarHBondContact O-N 3.42Å; T369-H391 HydrophobicContact CG2-CB 3.75Å; T369-F393 HydrophobicContact CG2-CB 3.8Å; T369-F393 HydrophobicContact CG2-CG 4.41Å; T369-H401 PolarHBondContact O-CE1 3.01Å
370S97.9Very high97.8Very high9 Ų920.9 Ų20.96%0.06311%0.11CC..  trans-83.826.2176.8-54.60000112.6M367 Y372 S445 T446M367-S370 WeakPolarHBondContact O-CB 3.1Å; M367-S370 PolarHBondContact O-N 3.46Å; M367-S370 VanDerWaalsContact O-N 3.15Å; S370-Y372 PolarHBondContact O-N 3.31Å; S370-S445 WeakPolarHBondContact O-CA 3.3Å; S370-T446 WeakPolarHBondContact CB-O 3.47Å; S370-T446 PolarHBondContact O-N 2.93Å
371T97.3Very high97.7Very high0 Ų021.2 Ų21.20%011%0.114CC..  trans-8984.5179.358.60000108.5V317 G368 T369 L389 H391 H401 A404 T443 T444V317-T371 HydrophobicContact CG1-CG2 3.88Å; G368-T371 WeakPolarHBondContact O-CG2 3.47Å; T369-T371 PolarHBondContact O-N 3.42Å; T371-L389 HydrophobicContact CG2-CD1 4.44Å; T371-H391 PolarHBondContact OG1-NE2 3.27Å; T371-H401 WeakPolarHBondContact O-CB 3.1Å; T371-H401 PolarHBondContact O-ND1 3.12Å; T371-A404 VanDerWaalsContact O-CB 3.3Å; T371-A404 WeakPolarHBondContact O-CB 3.45Å; T371-T443 WeakPolarHBondContact CG2-OG1 3.22Å; T371-T444 VanDerWaalsContact CA-O 3.29Å; T371-T444 WeakPolarHBondContact CA-O 3.33Å; T371-T444 WeakPolarHBondContact CB-O 3.32Å; T371-T444 WeakPolarHBondContact CG2-O 3.47Å
372Y98.3Very high97.4Very high73 Ų7323.9 Ų23.929%0.28613%0.127SC..  trans-82.1179.1-178.2-59.2-63000112.6S370 L374 T446 Y739S370-Y372 PolarHBondContact O-N 3.31Å; Y372-L374 PolarHBondContact O-N 3.48Å; Y372-T446 WeakPolarHBondContact CE2-O 3.11Å; Y372-Y739 AromaticContact CD1-CD1 3.77Å; Y372-Y739 HydrophobicContact CD1-CD1 3.77Å; Y372-Y739 HydrophobicContact CD1-CE1 4.03Å; Y372-Y739 HydrophobicContact CD1-CG 4.45Å; Y372-Y739 AromaticContact CE1-CD1 3.69Å; Y372-Y739 HydrophobicContact CE1-CD1 3.69Å; Y372-Y739 AromaticContact CE1-CE1 3.53Å; Y372-Y739 HydrophobicContact CE1-CE1 3.53Å; Y372-Y739 HydrophobicContact CE1-CG 4.31Å
373E98.6Very high97.2Very high14 Ų1424.9 Ų24.97%0.06513%0.132CC..  trans-62.6121.1-175.6-173175.6-170.300111.6K402 N403 Y735 N736 G737E373-K402 WeakPolarHBondContact CA-O 3.46Å; E373-K402 WeakPolarHBondContact CB-O 3.48Å; E373-K402 WeakPolarHBondContact CG-O 3.26Å; E373-N403 HydrophobicContact CG-CB 3.99Å; E373-N403 PolarHBondContact OE1-ND2 3.16Å; E373-Y735 HydrophobicContact CB-CE2 3.89Å; E373-Y735 HydrophobicContact CG-CD2 4.11Å; E373-Y735 HydrophobicContact CG-CE2 3.82Å; E373-Y735 VanDerWaalsContact O-CE2 3.29Å; E373-Y735 WeakPolarHBondContact O-CE2 3.49Å; E373-Y735 PolarHBondContact O-OH 3.16Å; E373-N736 VanDerWaalsContact CD-N 3.33Å; E373-N736 PolarHBondContact OE1-N 3.06Å; E373-N736 VanDerWaalsContact OE1-N 3.11Å; E373-N736 VanDerWaalsContact OE2-CA 3.29Å; E373-N736 WeakPolarHBondContact OE2-CA 3.19Å; E373-N736 WeakPolarHBondContact OE2-CB 3.34Å; E373-N736 PolarHBondContact OE2-N 3.06Å; E373-G737 PolarHBondContact OE2-N 3.38Å
374L98.8Very high97.2Very high1 Ų125.3 Ų25.31%0.00514%0.135CC..  trans-77.2128.7172.8-59.5168.7000109.6Y372 P376 D379 F386 N403 C406 T444Y372-L374 PolarHBondContact O-N 3.48Å; L374-P376 VanDerWaalsContact O-CD 3.31Å; L374-P376 WeakPolarHBondContact O-CD 3.48Å; L374-D379 WeakPolarHBondContact CA-OD2 3.4Å; L374-D379 HydrophobicContact CB-CB 4.06Å; L374-D379 HydrophobicContact CD2-CB 3.97Å; L374-F386 HydrophobicContact CB-CD1 4.21Å; L374-F386 HydrophobicContact CB-CE1 3.88Å; L374-N403 VanDerWaalsContact CB-O 3.23Å; L374-N403 WeakPolarHBondContact CB-O 3.22Å; L374-N403 VanDerWaalsContact CG-O 3.26Å; L374-N403 WeakPolarHBondContact CG-O 3.4Å; L374-N403 PolarHBondContact N-O 2.78Å; L374-C406 HydrophobicContact CD1-CB 3.96Å; L374-T444 HydrophobicContact CD2-CG2 3.55Å
375A98.3Very high97.2Very high10 Ų1027.2 Ų27.28%0.08315%0.146CC..  trans-80.4114.1-178.800000111.5G377 I378 D379 F733 Y735A375-G377 PolarHBondContact O-N 3.03Å; A375-I378 HydrophobicContact CB-CB 4.23Å; A375-I378 HydrophobicContact CB-CD1 4.38Å; A375-I378 PolarHBondContact O-N 2.99Å; A375-I378 VanDerWaalsContact O-N 3.15Å; A375-D379 WeakPolarHBondContact CB-OD2 3.2Å; A375-D379 PolarHBondContact N-OD2 3.17Å; A375-D379 PolarHBondContact O-N 3.25Å; A375-F733 HydrophobicContact CB-CE2 4.03Å; A375-F733 HydrophobicContact CB-CZ 4.22Å; A375-Y735 HydrophobicContact CB-CD2 4.04Å; A375-Y735 HydrophobicContact CB-CE2 4.08Å
376P96.8Very high97.2Very high26 Ų2626.7 Ų26.717%0.16915%0.146CC..BIsolated β-bridgetrans-62.8132.1-179.8-21.834.1000112.7L374 I378 F386 F733L374-P376 VanDerWaalsContact O-CD 3.31Å; L374-P376 WeakPolarHBondContact O-CD 3.48Å; P376-I378 VanDerWaalsContact C-N 3.32Å; P376-F386 HydrophobicContact CB-CE2 3.82Å; P376-F386 HydrophobicContact CB-CZ 3.75Å; P376-F386 HydrophobicContact CG-CD2 4.45Å; P376-F386 HydrophobicContact CG-CE1 4.3Å; P376-F386 HydrophobicContact CG-CE2 3.84Å; P376-F386 HydrophobicContact CG-CZ 3.76Å; P376-F733 WeakPolarHBondContact O-CD2 3.47Å
377G94.4Very high97.2Very high22 Ų2228.2 Ų28.223%0.22716%0.155CC..THydrogen-bonded Turntrans86.5-4.4-176.500000115.1A375 C380 E382A375-G377 PolarHBondContact O-N 3.03Å; G377-C380 WeakPolarHBondContact CA-O 3.26Å; G377-C380 PolarHBondContact N-O 3.09Å; G377-E382 WeakPolarHBondContact CA-OE1 3.35Å
378I96.8Very high97.2Very high129 Ų12930.5 Ų30.566%0.66217%0.167SC*.THydrogen-bonded Turntrans-120.1-69.8176.6-56.5175.2000109.2A375 P376 F733A375-I378 HydrophobicContact CB-CB 4.23Å; A375-I378 HydrophobicContact CB-CD1 4.38Å; A375-I378 PolarHBondContact O-N 2.99Å; A375-I378 VanDerWaalsContact O-N 3.15Å; P376-I378 VanDerWaalsContact C-N 3.32Å; I378-F733 HydrophobicContact CD1-CE2 4.32Å
379D98.4Very high97.2Very high50 Ų5031.1 Ų31.127%0.26717%0.171SC..THydrogen-bonded Turntrans-73.4-35.3-177.3-65.5-40.4000112.1L374 A375 R442L374-D379 WeakPolarHBondContact CA-OD2 3.4Å; L374-D379 HydrophobicContact CB-CB 4.06Å; L374-D379 HydrophobicContact CD2-CB 3.97Å; A375-D379 WeakPolarHBondContact CB-OD2 3.2Å; A375-D379 PolarHBondContact N-OD2 3.17Å; A375-D379 PolarHBondContact O-N 3.25Å; D379-R442 WeakPolarHBondContact O-CD 3.35Å; D379-R442 PolarHBondContact O-NH1 3.42Å
380C98.1Very high97.2Very high3 Ų334.1 Ų34.12%0.0218%0.181CC..BIsolated β-bridgetrans-138.8154.3172.9-45.90000109.3G377 A384 F386 C406 F408G377-C380 WeakPolarHBondContact CA-O 3.26Å; G377-C380 PolarHBondContact N-O 3.09Å; C380-A384 HydrophobicContact CB-CB 3.92Å; C380-F386 HydrophobicContact CB-CE1 3.93Å; C380-F386 HydrophobicContact CB-CZ 3.81Å; C380-C406 HydrophobicContact CB-CB 3.74Å; C380-C406 WeakPolarHBondContact CB-SG 3.44Å; C380-C406 WeakPolarHBondContact SG-CB 3.17Å; C380-C406 CovalentContact SG-SG 2.02Å; C380-C406 PolarHBondContact SG-SG 2.94Å; C380-F408 HydrophobicContact CB-CD1 4.18Å; C380-F408 HydrophobicContact CB-CE1 4.08Å
381P95.9Very high97.3Very high23 Ų2334 Ų3415%0.14918%0.179CC..  trans-52.8149.3173.6-26.235.8000112.3L291 I383 A384 F408L291-P381 HydrophobicContact CB-CB 4.35Å; L291-P381 HydrophobicContact CD2-CB 4.08Å; L291-P381 HydrophobicContact CD2-CG 3.86Å; P381-I383 HydrophobicContact CB-CG1 3.83Å; P381-I383 PolarHBondContact O-N 3.14Å; P381-I383 VanDerWaalsContact O-N 3.08Å; P381-A384 WeakPolarHBondContact O-CB 3.13Å; P381-A384 PolarHBondContact O-N 3.27Å; P381-F408 HydrophobicContact CG-CD2 3.61Å; P381-F408 HydrophobicContact CG-CE2 3.76Å; P381-F408 HydrophobicContact CG-CG 4.09Å; P381-F408 HydrophobicContact CG-CZ 4.38Å
382E93Very high97.3Very high58 Ų5834 Ų3427%0.27118%0.179SC..THydrogen-bonded Turntrans-58.9-26.7-178.7-6386168.100113K290 G377 A384 T729K290-E382 WeakPolarHBondContact CD-OE1 3.26Å; K290-E382 VanDerWaalsContact CE-OE1 3.27Å; K290-E382 WeakPolarHBondContact CE-OE1 3.33Å; K290-E382 IonicContact NZ-OE1 2.71Å; K290-E382 PolarHBondContact NZ-OE1 3.33Å; G377-E382 WeakPolarHBondContact CA-OE1 3.35Å; E382-A384 VanDerWaalsContact C-N 3.29Å; E382-T729 HydrophobicContact CB-CG2 3.95Å; E382-T729 HydrophobicContact CG-CG2 4.4Å
383I93.1Very high97.3Very high30 Ų3032.5 Ų32.515%0.15417%0.174CC..THydrogen-bonded Turntrans-81.1-2.2178.458.6160.3000113.6L291 E293 H297 P381L291-I383 HydrophobicContact CB-CD1 4.49Å; L291-I383 HydrophobicContact CD2-CD1 3.96Å; L291-I383 HydrophobicContact CG-CD1 3.89Å; E293-I383 HydrophobicContact CB-CD1 4.21Å; E293-I383 HydrophobicContact CG-CD1 3.53Å; H297-I383 PolarHBondContact CE1-O 2.77Å; H297-I383 VanDerWaalsContact CE1-O 3.23Å; P381-I383 HydrophobicContact CB-CG1 3.83Å; P381-I383 PolarHBondContact O-N 3.14Å; P381-I383 VanDerWaalsContact O-N 3.08Å
384A97Very high97.2Very high11 Ų1132.9 Ų32.99%0.09118%0.176CC..SBendtrans-65.2148.8-178.600000111.9C380 P381 E382 F386 C406 F408C380-A384 HydrophobicContact CB-CB 3.92Å; P381-A384 WeakPolarHBondContact O-CB 3.13Å; P381-A384 PolarHBondContact O-N 3.27Å; E382-A384 VanDerWaalsContact C-N 3.29Å; A384-F386 HydrophobicContact CB-CD2 4.33Å; A384-F386 HydrophobicContact CB-CE2 3.8Å; A384-F386 HydrophobicContact CB-CZ 4.01Å; A384-F386 VanDerWaalsContact O-CD2 3.32Å; A384-F386 WeakPolarHBondContact O-CD2 3.26Å; A384-F386 PolarHBondContact O-N 3.4Å; A384-C406 HydrophobicContact CB-CB 4.16Å; A384-F408 HydrophobicContact CB-CB 3.76Å; A384-F408 HydrophobicContact CB-CD1 4.13Å; A384-F408 HydrophobicContact CB-CG 4.28Å
385T97.8Very high97Very high42 Ų4233.2 Ų33.226%0.25818%0.179SC..EExtended strand (participates in β ladder)trans-80.4110.6164.9-59.20000108.5Y299 I301 C406 I407Y299-T385 PolarHBondContact OH-OG1 2.89Å; Y299-T385 VanDerWaalsContact OH-OG1 3.09Å; I301-T385 HydrophobicContact CD1-CG2 3.67Å; T385-C406 CarbonylContact O-C 3.54Å; T385-C406 WeakPolarHBondContact O-CA 3.35Å; T385-I407 PolarHBondContact N-O 3.19Å; T385-I407 PolarHBondContact O-N 2.82Å
386F98.1Very high96.8Very high43 Ų4334.5 Ų34.519%0.18918%0.184CC..EExtended strand (participates in β ladder)trans-89.5141.9175.3-66.3-89.8000111.4L374 P376 C380 A384 N403 L405 C406L374-F386 HydrophobicContact CB-CD1 4.21Å; L374-F386 HydrophobicContact CB-CE1 3.88Å; P376-F386 HydrophobicContact CB-CE2 3.82Å; P376-F386 HydrophobicContact CB-CZ 3.75Å; P376-F386 HydrophobicContact CG-CD2 4.45Å; P376-F386 HydrophobicContact CG-CE1 4.3Å; P376-F386 HydrophobicContact CG-CE2 3.84Å; P376-F386 HydrophobicContact CG-CZ 3.76Å; C380-F386 HydrophobicContact CB-CE1 3.93Å; C380-F386 HydrophobicContact CB-CZ 3.81Å; A384-F386 HydrophobicContact CB-CD2 4.33Å; A384-F386 HydrophobicContact CB-CE2 3.8Å; A384-F386 HydrophobicContact CB-CZ 4.01Å; A384-F386 VanDerWaalsContact O-CD2 3.32Å; A384-F386 WeakPolarHBondContact O-CD2 3.26Å; A384-F386 PolarHBondContact O-N 3.4Å; F386-N403 HydrophobicContact CB-CB 3.87Å; F386-N403 WeakPolarHBondContact CB-OD1 3.44Å; F386-N403 HydrophobicContact CD1-CB 3.81Å; F386-N403 HydrophobicContact CG-CB 4.11Å; F386-L405 CarbonylContact C-O 3.55Å; F386-L405 WeakPolarHBondContact CA-O 3.15Å; F386-C406 HydrophobicContact CD1-CB 3.76Å; F386-C406 HydrophobicContact CE1-CB 3.8Å; F386-C406 HydrophobicContact CG-CB 4.44Å; F386-C406 HydrophobicContact CZ-CB 4.47Å
387V98.3Very high96.8Very high32 Ų3238.3 Ų38.319%0.19420%0.198CC..EExtended strand (participates in β ladder)trans-128.7128.6-174.4-177.20000109.4N403 A404 L405V387-N403 CarbonylContact O-C 3.47Å; V387-A404 PolarHBondContact O-N 3.1Å; V387-L405 HydrophobicContact CB-CB 4.33Å; V387-L405 HydrophobicContact CB-CD2 3.87Å; V387-L405 HydrophobicContact CG2-CD2 3.86Å; V387-L405 PolarHBondContact N-O 3.08Å; V387-L405 PolarHBondContact O-N 3.06Å; V387-L405 VanDerWaalsContact O-N 3.14Å
388D98.3Very high96.9Very high49 Ų4937.4 Ų37.426%0.26219%0.188SC..EExtended strand (participates in β ladder)trans-73.5139.9171.7-68.9-3.3000110.5Y390 R400 H401 K402 N403D388-Y390 HydrophobicContact CB-CE2 4.22Å; D388-R400 HydrophobicContact CB-CG 4.38Å; D388-R400 WeakPolarHBondContact OD2-CD 3.23Å; D388-R400 IonicContact OD2-NE 3.31Å; D388-R400 IonicContact OD2-NH1 3.3Å; D388-H401 CarbonylContact C-O 3.13Å; D388-H401 WeakPolarHBondContact CA-O 3.21Å; D388-K402 VanDerWaalsContact OD1-CA 3.26Å; D388-K402 WeakPolarHBondContact OD1-CA 3.49Å; D388-K402 WeakPolarHBondContact OD1-CG 3.39Å; D388-N403 PolarHBondContact OD1-N 3.18Å
389L98.2Very high97Very high13 Ų1332.3 Ų32.37%0.06816%0.163CC..EExtended strand (participates in β ladder)trans-111.5157.5172.5-61.2178000110.9V317 T371 H401 A404 L405V317-L389 HydrophobicContact CB-CD1 3.81Å; V317-L389 HydrophobicContact CB-CD2 4.41Å; V317-L389 HydrophobicContact CG1-CD1 3.98Å; V317-L389 HydrophobicContact CG2-CD1 3.7Å; V317-L389 HydrophobicContact CG2-CD2 4.19Å; T371-L389 HydrophobicContact CG2-CD1 4.44Å; L389-H401 HydrophobicContact CB-CB 4.49Å; L389-H401 PolarHBondContact N-O 3.43Å; L389-H401 PolarHBondContact O-N 3.23Å; L389-A404 HydrophobicContact CB-CB 3.95Å; L389-A404 HydrophobicContact CD1-CB 3.7Å; L389-A404 HydrophobicContact CG-CB 3.77Å; L389-L405 HydrophobicContact CD1-CB 4.28Å; L389-L405 HydrophobicContact CD2-CB 4.48Å; L389-L405 HydrophobicContact CG-CB 4.42Å
390Y98.5Very high97Very high79 Ų7934.4 Ų34.431%0.3117%0.167SC..EExtended strand (participates in β ladder)trans-132.9125.5-178.7-61-92.7000110.5V36 D388 T399 R400 V742V36-Y390 HydrophobicContact CG2-CD1 3.26Å; V36-Y390 HydrophobicContact CG2-CD2 4.45Å; V36-Y390 HydrophobicContact CG2-CE1 3.51Å; V36-Y390 HydrophobicContact CG2-CG 3.78Å; D388-Y390 HydrophobicContact CB-CE2 4.22Å; Y390-T399 VanDerWaalsContact CA-O 3.31Å; Y390-T399 WeakPolarHBondContact CA-O 3.31Å; Y390-R400 HydrophobicContact CD1-CB 3.93Å; Y390-R400 HydrophobicContact CD1-CG 4.11Å; Y390-R400 HydrophobicContact CE1-CB 3.66Å; Y390-R400 HydrophobicContact CE1-CG 3.52Å; Y390-V742 HydrophobicContact CD1-CG2 4Å; Y390-V742 HydrophobicContact CE1-CG2 4Å
391H98.4Very high97Very high5 Ų534.7 Ų34.72%0.02317%0.168CC..EExtended strand (participates in β ladder)trans-125.5152.1-176.8-60-68.5000111.2S319 G368 T369 T371 P398 T399 H401S319-H391 PolarHBondContact OG-ND1 3.03Å; G368-H391 PolarHBondContact O-CE1 3.19Å; G368-H391 PolarHBondContact O-NE2 3.33Å; T369-H391 HydrophobicContact CG2-CB 3.75Å; T371-H391 PolarHBondContact OG1-NE2 3.27Å; H391-P398 CarbonylContact O-C 3.58Å; H391-T399 PolarHBondContact N-O 3.3Å; H391-T399 PolarHBondContact O-N 3.37Å; H391-H401 AromaticContact CD2-CD2 3.6Å; H391-H401 AromaticContact CD2-CG 3.98Å; H391-H401 AromaticContact CD2-NE2 3.91Å
392Y98.4Very high97.1Very high2 Ų235.9 Ų35.91%0.00817%0.171CC..EExtended strand (participates in β ladder)trans-130.392.5170.1-166.3-66.7000107R43 I67 L69 M70 T395 D396 P398R43-Y392 PolarHBondContact NE-OH 3.03Å; I67-Y392 HydrophobicContact CB-CE1 4.16Å; I67-Y392 HydrophobicContact CG2-CD1 4.36Å; I67-Y392 HydrophobicContact CG2-CE1 3.84Å; L69-Y392 CarbonylContact C-O 3.56Å; L69-Y392 VanDerWaalsContact CA-O 3.3Å; L69-Y392 WeakPolarHBondContact CA-O 3.47Å; M70-Y392 HydrophobicContact CB-CD1 4.41Å; M70-Y392 HydrophobicContact CB-CG 4.25Å; M70-Y392 HydrophobicContact CE-CD1 4.37Å; M70-Y392 HydrophobicContact CE-CD2 4.45Å; M70-Y392 HydrophobicContact CE-CE1 4.06Å; M70-Y392 HydrophobicContact CE-CE2 4.12Å; M70-Y392 HydrophobicContact CG-CD1 3.81Å; M70-Y392 HydrophobicContact CG-CE1 4.35Å; M70-Y392 HydrophobicContact CG-CG 3.94Å; M70-Y392 PolarHBondContact N-O 3Å; M70-Y392 HydrophobicContact SD-CD1 4.28Å; M70-Y392 HydrophobicContact SD-CD2 4.06Å; M70-Y392 HydrophobicContact SD-CE2 4.31Å; M70-Y392 HydrophobicContact SD-CG 4.05Å; Y392-T395 HydrophobicContact CD1-CG2 4.02Å; Y392-T395 HydrophobicContact CD2-CG2 4.24Å; Y392-T395 HydrophobicContact CE1-CG2 4.23Å; Y392-T395 WeakPolarHBondContact CE1-O 3.29Å; Y392-T395 HydrophobicContact CE2-CG2 4.47Å; Y392-T395 HydrophobicContact CG-CG2 4.01Å; Y392-T395 PolarHBondContact OH-O 3.49Å; Y392-D396 WeakPolarHBondContact OH-CA 3.23Å; Y392-D396 PolarHBondContact OH-O 2.77Å; Y392-P398 HydrophobicContact CD2-CG 4.3Å
393F97.8Very high97.3Very high41 Ų4134.2 Ų34.218%0.1816%0.164CC..EExtended strand (participates in β ladder)trans-138126.4175.8179-112.2000108.5L68 L69 P140 A366 T369 T395L68-F393 HydrophobicContact CD1-CD2 4.43Å; L68-F393 HydrophobicContact CD1-CE2 3.97Å; L68-F393 HydrophobicContact CG-CD2 4.43Å; L68-F393 HydrophobicContact CG-CE2 4.1Å; L68-F393 CarbonylContact O-C 3.58Å; L68-F393 VanDerWaalsContact O-CA 3.26Å; L68-F393 WeakPolarHBondContact O-CA 3.43Å; L69-F393 HydrophobicContact CB-CD2 4.32Å; L69-F393 HydrophobicContact CD1-CB 4.06Å; L69-F393 HydrophobicContact CD1-CD2 3.85Å; L69-F393 HydrophobicContact CD1-CG 4.38Å; P140-F393 HydrophobicContact CB-CE2 4.36Å; P140-F393 HydrophobicContact CB-CZ 4Å; P140-F393 HydrophobicContact CG-CE2 4.4Å; P140-F393 HydrophobicContact CG-CZ 4.45Å; A366-F393 HydrophobicContact CB-CD1 4.03Å; A366-F393 HydrophobicContact CB-CD2 3.81Å; A366-F393 HydrophobicContact CB-CE1 3.96Å; A366-F393 HydrophobicContact CB-CE2 3.73Å; A366-F393 HydrophobicContact CB-CG 3.95Å; A366-F393 HydrophobicContact CB-CZ 3.81Å; T369-F393 HydrophobicContact CG2-CB 3.8Å; T369-F393 HydrophobicContact CG2-CG 4.41Å; F393-T395 VanDerWaalsContact C-N 3.27Å; F393-T395 WeakPolarHBondContact O-CG2 3.31Å; F393-T395 PolarHBondContact O-N 2.96Å
394D96.3Very high97.5Very high21 Ų2132.8 Ų32.811%0.11216%0.156CC..SBendtrans46.648.3179-165.533.5000113.9L68 T142 I143L68-D394 HydrophobicContact CD1-CB 4.4Å; L68-D394 PolarHBondContact O-N 2.94Å; T142-D394 VanDerWaalsContact CA-OD2 3.26Å; T142-D394 WeakPolarHBondContact CA-OD2 3.25Å; T142-D394 WeakPolarHBondContact CB-OD1 3.31Å; T142-D394 WeakPolarHBondContact CB-OD2 3.21Å; I143-D394 PolarHBondContact N-OD2 3.25Å
395T95.9Very high97.6Very high9 Ų932.2 Ų32.26%0.05515%0.152CC..SBendtrans-149.7164.1-173.1-176.60000110.5Y392 F393 K397Y392-T395 HydrophobicContact CD1-CG2 4.02Å; Y392-T395 HydrophobicContact CD2-CG2 4.24Å; Y392-T395 HydrophobicContact CE1-CG2 4.23Å; Y392-T395 WeakPolarHBondContact CE1-O 3.29Å; Y392-T395 HydrophobicContact CE2-CG2 4.47Å; Y392-T395 HydrophobicContact CG-CG2 4.01Å; Y392-T395 PolarHBondContact OH-O 3.49Å; F393-T395 VanDerWaalsContact C-N 3.27Å; F393-T395 WeakPolarHBondContact O-CG2 3.31Å; F393-T395 PolarHBondContact O-N 2.96Å; T395-K397 WeakPolarHBondContact CG2-O 3.25Å; T395-K397 PolarHBondContact OG1-N 3.45Å; T395-K397 PolarHBondContact OG1-O 2.57Å
396D93.9Very high97.7Very high36 Ų3630.2 Ų30.219%0.19314%0.14CC..SBendtrans-99.1-6.7175.3-73.2-58.1000113.9R43 D56 A57 R58 Y392R43-D396 VanDerWaalsContact CD-O 3.24Å; R43-D396 WeakPolarHBondContact CD-O 3.29Å; R43-D396 PolarHBondContact NE-O 3.04Å; R43-D396 IonicContact NH2-OD1 2.91Å; R43-D396 PolarHBondContact NH2-OD1 3.14Å; D56-D396 WeakPolarHBondContact CA-OD1 3.35Å; D56-D396 WeakPolarHBondContact CB-OD2 3.34Å; A57-D396 VanDerWaalsContact N-CG 3.28Å; A57-D396 PolarHBondContact N-OD1 2.85Å; A57-D396 PolarHBondContact N-OD2 3.07Å; A57-D396 VanDerWaalsContact N-OD2 3.07Å; R58-D396 PolarHBondContact N-OD2 3.17Å; Y392-D396 WeakPolarHBondContact OH-CA 3.23Å; Y392-D396 PolarHBondContact OH-O 2.77Å
397K95.9Very high97.7Very high107 Ų10728.2 Ų28.247%0.46513%0.131SC..SBendtrans-147.7150.7-178.451.2176.6176.6162.20110.7T395 T399 G741T395-K397 WeakPolarHBondContact CG2-O 3.25Å; T395-K397 PolarHBondContact OG1-N 3.45Å; T395-K397 PolarHBondContact OG1-O 2.57Å; K397-T399 PolarHBondContact O-N 2.75Å; K397-G741 PolarHBondContact NZ-O 2.85Å
398P97.8Very high97.7Very high3 Ų326.8 Ų26.82%0.01912%0.122CC..PPolyproline II helixtrans-55132.8174.4-24.435.9000111V36 M39 K40 H391 Y392 G741 V742V36-P398 HydrophobicContact CG1-CB 4.33Å; V36-P398 HydrophobicContact CG1-CG 4.18Å; V36-P398 HydrophobicContact CG2-CB 4.39Å; M39-P398 HydrophobicContact CB-CB 4.47Å; M39-P398 HydrophobicContact CB-CG 3.62Å; M39-P398 HydrophobicContact CE-CB 3.96Å; M39-P398 HydrophobicContact CE-CG 4.41Å; M39-P398 HydrophobicContact CG-CG 4.47Å; M39-P398 HydrophobicContact SD-CB 3.96Å; M39-P398 HydrophobicContact SD-CG 4.12Å; K40-P398 HydrophobicContact CG-CG 4.29Å; H391-P398 CarbonylContact O-C 3.58Å; Y392-P398 HydrophobicContact CD2-CG 4.3Å; P398-G741 CarbonylContact O-C 3.59Å; P398-G741 WeakPolarHBondContact O-CA 3.2Å; P398-V742 HydrophobicContact CB-CG2 4.27Å; P398-V742 WeakPolarHBondContact O-CG2 3.24Å; P398-V742 PolarHBondContact O-N 2.91Å
399T97.8Very high97.7Very high21 Ų2125.1 Ų25.113%0.12911%0.113CC..EExtended strand (participates in β ladder)trans-99.7127.6178.7-570000109.5Y390 H391 K397 Y739Y390-T399 VanDerWaalsContact CA-O 3.31Å; Y390-T399 WeakPolarHBondContact CA-O 3.31Å; H391-T399 PolarHBondContact N-O 3.3Å; H391-T399 PolarHBondContact O-N 3.37Å; K397-T399 PolarHBondContact O-N 2.75Å; T399-Y739 HydrophobicContact CG2-CD2 3.94Å
400R98.2Very high97.6Very high94 Ų9427.4 Ų27.436%0.35512%0.124SC..EExtended strand (participates in β ladder)trans-87.3127174-173.5-178.880175.11.5110.2D388 Y390 Y739 A740 V742D388-R400 HydrophobicContact CB-CG 4.38Å; D388-R400 WeakPolarHBondContact OD2-CD 3.23Å; D388-R400 IonicContact OD2-NE 3.31Å; D388-R400 IonicContact OD2-NH1 3.3Å; Y390-R400 HydrophobicContact CD1-CB 3.93Å; Y390-R400 HydrophobicContact CD1-CG 4.11Å; Y390-R400 HydrophobicContact CE1-CB 3.66Å; Y390-R400 HydrophobicContact CE1-CG 3.52Å; R400-Y739 WeakPolarHBondContact O-CA 3.43Å; R400-A740 PolarHBondContact N-O 2.84Å; R400-A740 PolarHBondContact O-N 3.04Å; R400-V742 HydrophobicContact CB-CG1 3.84Å; R400-V742 HydrophobicContact CB-CG2 4.37Å
401H98.2Very high97.4Very high10 Ų1026.3 Ų26.35%0.04613%0.125CC..EExtended strand (participates in β ladder)trans-106.9107169.6-68.8-117.4000107.9T369 T371 D388 L389 H391 A404T369-H401 PolarHBondContact O-CE1 3.01Å; T371-H401 WeakPolarHBondContact O-CB 3.1Å; T371-H401 PolarHBondContact O-ND1 3.12Å; D388-H401 CarbonylContact C-O 3.13Å; D388-H401 WeakPolarHBondContact CA-O 3.21Å; L389-H401 HydrophobicContact CB-CB 4.49Å; L389-H401 PolarHBondContact N-O 3.43Å; L389-H401 PolarHBondContact O-N 3.23Å; H391-H401 AromaticContact CD2-CD2 3.6Å; H391-H401 AromaticContact CD2-CG 3.98Å; H391-H401 AromaticContact CD2-NE2 3.91Å; H401-A404 HydrophobicContact CB-CB 3.77Å
402K97.5Very high97.2Very high47 Ų4727.8 Ų27.820%0.20414%0.135CC..EExtended strand (participates in β ladder)trans-72.9141.4-175.1-171.7-179.4177.1-1770110.2E373 D388 A404 N736E373-K402 WeakPolarHBondContact CA-O 3.46Å; E373-K402 WeakPolarHBondContact CB-O 3.48Å; E373-K402 WeakPolarHBondContact CG-O 3.26Å; D388-K402 VanDerWaalsContact OD1-CA 3.26Å; D388-K402 WeakPolarHBondContact OD1-CA 3.49Å; D388-K402 WeakPolarHBondContact OD1-CG 3.39Å; K402-A404 PolarHBondContact O-N 2.9Å; K402-N736 HydrophobicContact CD-CB 4.2Å
403N97.8Very high96.9Very high23 Ų2332.5 Ų32.512%0.12317%0.174CC..EExtended strand (participates in β ladder)trans46.735.9177.9-55.1-27.3000113.9E373 L374 F386 V387 D388 L405E373-N403 HydrophobicContact CG-CB 3.99Å; E373-N403 PolarHBondContact OE1-ND2 3.16Å; L374-N403 VanDerWaalsContact CB-O 3.23Å; L374-N403 WeakPolarHBondContact CB-O 3.22Å; L374-N403 VanDerWaalsContact CG-O 3.26Å; L374-N403 WeakPolarHBondContact CG-O 3.4Å; L374-N403 PolarHBondContact N-O 2.78Å; F386-N403 HydrophobicContact CB-CB 3.87Å; F386-N403 WeakPolarHBondContact CB-OD1 3.44Å; F386-N403 HydrophobicContact CD1-CB 3.81Å; F386-N403 HydrophobicContact CG-CB 4.11Å; V387-N403 CarbonylContact O-C 3.47Å; D388-N403 PolarHBondContact OD1-N 3.18Å; N403-L405 VanDerWaalsContact C-N 3.28Å; N403-L405 PolarHBondContact O-N 2.91Å
404A98.4Very high96.8Very high0 Ų036.7 Ų36.70%020%0.196CC..EExtended strand (participates in β ladder)trans-78.3-14-171.700000113.5T371 V387 L389 H401 K402 T443T371-A404 VanDerWaalsContact O-CB 3.3Å; T371-A404 WeakPolarHBondContact O-CB 3.45Å; V387-A404 PolarHBondContact O-N 3.1Å; L389-A404 HydrophobicContact CB-CB 3.95Å; L389-A404 HydrophobicContact CD1-CB 3.7Å; L389-A404 HydrophobicContact CG-CB 3.77Å; H401-A404 HydrophobicContact CB-CB 3.77Å; K402-A404 PolarHBondContact O-N 2.9Å; A404-T443 PolarHBondContact O-OG1 3.19Å
405L98.8Very high96.8Very high0 Ų039.1 Ų39.10%021%0.212CC..EExtended strand (participates in β ladder)trans-134.4146174.9176.6142.8000109.7Y315 V317 L323 F386 V387 L389 N403 I407 L441 R442Y315-L405 HydrophobicContact CD2-CD1 3.98Å; Y315-L405 HydrophobicContact CE2-CD1 3.87Å; Y315-L405 HydrophobicContact CE2-CD2 3.87Å; V317-L405 HydrophobicContact CG2-CD1 3.71Å; L323-L405 HydrophobicContact CD1-CD1 3.83Å; F386-L405 CarbonylContact C-O 3.55Å; F386-L405 WeakPolarHBondContact CA-O 3.15Å; V387-L405 HydrophobicContact CB-CB 4.33Å; V387-L405 HydrophobicContact CB-CD2 3.87Å; V387-L405 HydrophobicContact CG2-CD2 3.86Å; V387-L405 PolarHBondContact N-O 3.08Å; V387-L405 PolarHBondContact O-N 3.06Å; V387-L405 VanDerWaalsContact O-N 3.14Å; L389-L405 HydrophobicContact CD1-CB 4.28Å; L389-L405 HydrophobicContact CD2-CB 4.48Å; L389-L405 HydrophobicContact CG-CB 4.42Å; N403-L405 VanDerWaalsContact C-N 3.28Å; N403-L405 PolarHBondContact O-N 2.91Å; L405-I407 HydrophobicContact CD2-CD1 4.07Å; L405-I407 HydrophobicContact CD2-CG1 3.97Å; L405-L441 HydrophobicContact CD1-CD1 3.93Å; L405-L441 HydrophobicContact CD2-CD1 3.77Å; L405-L441 HydrophobicContact CG-CD1 4.08Å; L405-R442 CarbonylContact C-O 3.58Å; L405-R442 WeakPolarHBondContact CA-O 3.46Å; L405-R442 WeakPolarHBondContact CG-O 3.48Å
406C98.8Very high96.9Very high0 Ų040.4 Ų40.40%022%0.219CC..EExtended strand (participates in β ladder)trans-132.3146.8176.178.30000111.7L374 C380 A384 T385 F386 R442L374-C406 HydrophobicContact CD1-CB 3.96Å; C380-C406 HydrophobicContact CB-CB 3.74Å; C380-C406 WeakPolarHBondContact CB-SG 3.44Å; C380-C406 WeakPolarHBondContact SG-CB 3.17Å; C380-C406 CovalentContact SG-SG 2.02Å; C380-C406 PolarHBondContact SG-SG 2.94Å; A384-C406 HydrophobicContact CB-CB 4.16Å; T385-C406 CarbonylContact O-C 3.54Å; T385-C406 WeakPolarHBondContact O-CA 3.35Å; F386-C406 HydrophobicContact CD1-CB 3.76Å; F386-C406 HydrophobicContact CE1-CB 3.8Å; F386-C406 HydrophobicContact CG-CB 4.44Å; F386-C406 HydrophobicContact CZ-CB 4.47Å; C406-R442 PolarHBondContact N-O 2.83Å; C406-R442 PolarHBondContact O-N 2.96Å
407I98.9Very high97.1Very high0 Ų041.8 Ų41.80%022%0.222CC..EExtended strand (participates in β ladder)trans-127.4127.7176.2-60.5163.8000107.9Y299 I301 V306 Y315 T385 L405 L439 V440 L441Y299-I407 HydrophobicContact CD2-CG2 4.05Å; Y299-I407 HydrophobicContact CE2-CB 4.49Å; Y299-I407 HydrophobicContact CE2-CG2 3.84Å; Y299-I407 PolarHBondContact OH-O 3.02Å; Y299-I407 VanDerWaalsContact OH-O 3.07Å; I301-I407 HydrophobicContact CD1-CB 3.93Å; I301-I407 HydrophobicContact CD1-CD1 3.53Å; I301-I407 HydrophobicContact CD1-CG1 4.31Å; I301-I407 HydrophobicContact CD1-CG2 4.04Å; I301-I407 HydrophobicContact CG1-CD1 4.02Å; V306-I407 HydrophobicContact CG2-CD1 4.01Å; Y315-I407 HydrophobicContact CE1-CD1 3.92Å; T385-I407 PolarHBondContact N-O 3.19Å; T385-I407 PolarHBondContact O-N 2.82Å; L405-I407 HydrophobicContact CD2-CD1 4.07Å; L405-I407 HydrophobicContact CD2-CG1 3.97Å; I407-L439 HydrophobicContact CG2-CD1 3.88Å; I407-L439 HydrophobicContact CG2-CG 4.36Å; I407-V440 WeakPolarHBondContact CA-O 3.2Å; I407-L441 HydrophobicContact CD1-CD1 3.9Å; I407-L441 HydrophobicContact CG1-CD1 3.5Å; I407-L441 VanDerWaalsContact CG1-CD1 3.5Å
408F98.6Very high97.3Very high3 Ų343.1 Ų43.11%0.01322%0.223CC..EExtended strand (participates in β ladder)trans-154154.5-179.360.9-84.6000112.2C380 P381 A384 M410 L439 V440C380-F408 HydrophobicContact CB-CD1 4.18Å; C380-F408 HydrophobicContact CB-CE1 4.08Å; P381-F408 HydrophobicContact CG-CD2 3.61Å; P381-F408 HydrophobicContact CG-CE2 3.76Å; P381-F408 HydrophobicContact CG-CG 4.09Å; P381-F408 HydrophobicContact CG-CZ 4.38Å; A384-F408 HydrophobicContact CB-CB 3.76Å; A384-F408 HydrophobicContact CB-CD1 4.13Å; A384-F408 HydrophobicContact CB-CG 4.28Å; F408-M410 HydrophobicContact CD2-CB 4.2Å; F408-M410 HydrophobicContact CD2-CG 4.39Å; F408-M410 HydrophobicContact CE2-CB 4.16Å; F408-M410 HydrophobicContact CE2-CG 4.01Å; F408-M410 HydrophobicContact CE2-SD 3.85Å; F408-L439 CarbonylContact O-C 3.56Å; F408-L439 WeakPolarHBondContact O-CA 3.27Å; F408-V440 HydrophobicContact CD1-CB 4.18Å; F408-V440 HydrophobicContact CD2-CB 4.25Å; F408-V440 HydrophobicContact CD2-CG2 4.32Å; F408-V440 HydrophobicContact CE1-CB 3.75Å; F408-V440 HydrophobicContact CE1-CG1 3.78Å; F408-V440 HydrophobicContact CE2-CB 3.84Å; F408-V440 HydrophobicContact CE2-CG1 4.4Å; F408-V440 HydrophobicContact CE2-CG2 3.74Å; F408-V440 HydrophobicContact CG-CB 4.42Å; F408-V440 HydrophobicContact CZ-CB 3.57Å; F408-V440 HydrophobicContact CZ-CG1 3.67Å; F408-V440 HydrophobicContact CZ-CG2 3.86Å; F408-V440 PolarHBondContact N-O 3.14Å; F408-V440 VanDerWaalsContact N-O 3.07Å; F408-V440 PolarHBondContact O-N 2.84Å
409E97.8Very high97.3Very high13 Ų1347.4 Ų47.46%0.06124%0.243CC..EExtended strand (participates in β ladder)trans-95142.8166.8176.4167.7-138.500109.6L291 R298 Y299 Y308 T437 V438L291-E409 VanDerWaalsContact CD2-O 3.26Å; L291-E409 WeakPolarHBondContact CD2-O 3.35Å; R298-E409 IonicContact CZ-OE1 2.69Å; R298-E409 IonicContact CZ-OE2 2.56Å; R298-E409 IonicContact NE-OE1 3.54Å; R298-E409 IonicContact NE-OE2 3.58Å; R298-E409 PolarHBondContact NE-OE2 3.44Å; R298-E409 IonicContact NH2-OE1 2.67Å; R298-E409 PolarHBondContact NH2-OE1 3.12Å; R298-E409 IonicContact NH2-OE2 3.82Å; R298-E409 PolarHBondContact NH2-OE2 3.12Å; Y299-E409 HydrophobicContact CD1-CB 4.32Å; Y299-E409 HydrophobicContact CE1-CB 4.38Å; Y308-E409 VanDerWaalsContact CE2-OE1 3.22Å; Y308-E409 WeakPolarHBondContact CE2-OE1 3.33Å; Y308-E409 PolarHBondContact OH-OE1 3.18Å; E409-T437 VanDerWaalsContact OE1-CB 3.24Å; E409-T437 WeakPolarHBondContact OE1-CB 3.48Å; E409-T437 PolarHBondContact OE1-OG1 2.93Å; E409-V438 CarbonylContact C-O 3.49Å; E409-V438 WeakPolarHBondContact CA-O 3.26Å
410M96.2Very high97.3Very high61 Ų6151.1 Ų51.130%0.326%0.258SS..EExtended strand (participates in β ladder)trans-141.1150.9172.262.2170.6-83.900112.6L291 F408 T437 V438 V440L291-M410 HydrophobicContact CD2-CB 3.72Å; F408-M410 HydrophobicContact CD2-CB 4.2Å; F408-M410 HydrophobicContact CD2-CG 4.39Å; F408-M410 HydrophobicContact CE2-CB 4.16Å; F408-M410 HydrophobicContact CE2-CG 4.01Å; F408-M410 HydrophobicContact CE2-SD 3.85Å; M410-T437 CarbonylContact O-C 3.57Å; M410-T437 WeakPolarHBondContact O-CA 3.3Å; M410-V438 HydrophobicContact CG-CG2 3.61Å; M410-V438 PolarHBondContact N-O 3.39Å; M410-V438 PolarHBondContact O-N 2.88Å; M410-V438 HydrophobicContact SD-CG2 4.42Å; M410-V440 HydrophobicContact CG-CG2 4.05Å; M410-V440 HydrophobicContact SD-CG2 4.09Å
411T93.8Very high97.3Very high56 Ų5649 Ų4934%0.34425%0.253SS..EExtended strand (participates in β ladder)trans-81.7134.5167.8550000110A413 E435 N436 T437T411-A413 PolarHBondContact O-N 3.01Å; T411-E435 HydrophobicContact CG2-CG 4.3Å; T411-E435 WeakPolarHBondContact CG2-OE1 3.24Å; T411-N436 WeakPolarHBondContact CA-O 3.4Å; T411-T437 HydrophobicContact CG2-CG2 3.96Å
412T95Very high97.3Very high37 Ų3750 Ų5023%0.22726%0.261CS..EExtended strand (participates in β ladder)trans-84.610.5-179.581.40000113.8M414 N436 V438T412-M414 PolarHBondContact O-N 2.87Å; T412-N436 HydrophobicContact CG2-CB 4.26Å; T412-N436 VanDerWaalsContact CG2-ND2 3.34Å; T412-N436 WeakPolarHBondContact CG2-ND2 3.39Å; T412-N436 PolarHBondContact N-O 3.05Å; T412-N436 WeakPolarHBondContact OG1-CB 3.2Å; T412-N436 PolarHBondContact OG1-ND2 2.86Å; T412-V438 HydrophobicContact CG2-CB 4.46Å; T412-V438 HydrophobicContact CG2-CG1 3.72Å; T412-V438 HydrophobicContact CG2-CG2 3.87Å
413A91.9Very high97.2Very high100 Ų10050.5 Ų50.583%0.82627%0.266SS*.EExtended strand (participates in β ladder)trans52.918.6-172.400000114.9T411T411-A413 PolarHBondContact O-N 3.01Å
414M95.3Very high97.2Very high130 Ų13058.1 Ų58.164%0.6430%0.299SS*.EExtended strand (participates in β ladder)trans-130.8145174.8-68.1-175.366.700109T412 N436T412-M414 PolarHBondContact O-N 2.87Å; M414-N436 WeakPolarHBondContact O-CB 3.26Å; M414-N436 PolarHBondContact O-N 3.18Å
415P97.5Very high97.1Very high71 Ų7167.1 Ų67.146%0.46134%0.338SS..EExtended strand (participates in β ladder)trans-71.2137.117129.2-32.8000109.9R417 R418 L434P415-R417 PolarHBondContact O-N 2.98Å; P415-R418 HydrophobicContact CB-CB 4.15Å; P415-R418 HydrophobicContact CB-CG 4.29Å; P415-R418 HydrophobicContact CG-CB 4.21Å; P415-R418 HydrophobicContact CG-CG 3.8Å; P415-L434 CarbonylContact C-O 3.58Å; P415-L434 VanDerWaalsContact CA-O 3.28Å; P415-L434 WeakPolarHBondContact CA-O 3.35Å; P415-L434 WeakPolarHBondContact CB-O 3.23Å
416L97.9Very high96.8Very high36 Ų3671.4 Ų71.419%0.18838%0.382CS..EExtended strand (participates in β ladder)trans-61.2-39.8174.1179.261.2000110.3L434 N436 P460 N461L416-L434 HydrophobicContact CB-CG 4.36Å; L416-L434 HydrophobicContact CD2-CD2 3.84Å; L416-L434 HydrophobicContact CD2-CG 4.4Å; L416-L434 PolarHBondContact N-O 3.27Å; L416-N436 HydrophobicContact CB-CB 3.92Å; L416-P460 HydrophobicContact CD2-CB 4.26Å; L416-P460 HydrophobicContact CD2-CG 4.46Å; L416-N461 HydrophobicContact CD1-CB 4.36Å; L416-N461 HydrophobicContact CD2-CB 4.27Å
417R98.1Very high96.6Very high66 Ų6672.5 Ų72.525%0.24939%0.393CS..EExtended strand (participates in β ladder)trans-154.5148.2171.755.3176.1174.972.56.8110.3P415 G433 L434 D695 S697 T703P415-R417 PolarHBondContact O-N 2.98Å; R417-G433 WeakPolarHBondContact O-CA 3.45Å; R417-L434 HydrophobicContact CG-CB 4Å; R417-L434 PolarHBondContact O-N 3.06Å; R417-D695 WeakPolarHBondContact CD-OD2 3.42Å; R417-D695 IonicContact NE-OD2 3.39Å; R417-D695 PolarHBondContact NE-OD2 3.42Å; R417-S697 PolarHBondContact NE-OG 2.99Å; R417-S697 VanDerWaalsContact NE-OG 3.14Å; R417-T703 PolarHBondContact NH2-OG1 2.83Å
418R98.1Very high96.4Very high134 Ų13474.9 Ų74.951%0.50640%0.402SS..EExtended strand (participates in β ladder)trans-155.8150.4176.766.1117.1-43.1-151.613.5111.8P415 G432P415-R418 HydrophobicContact CB-CB 4.15Å; P415-R418 HydrophobicContact CB-CG 4.29Å; P415-R418 HydrophobicContact CG-CB 4.21Å; P415-R418 HydrophobicContact CG-CG 3.8Å; R418-G432 CarbonylContact C-O 3.58Å; R418-G432 WeakPolarHBondContact CA-O 3.3Å
419H98.5Very high96.4Very high94 Ų9478.6 Ų78.644%0.43542%0.422SS..EExtended strand (participates in β ladder)trans-149149.4173-17570.8000111.1N421 F430 F431 G432H419-N421 PolarHBondContact NE2-ND2 3.44Å; H419-F430 AromaticContact CD2-CZ 3.95Å; H419-F431 WeakPolarHBondContact O-CA 3.47Å; H419-F431 WeakPolarHBondContact O-CD2 3.25Å; H419-G432 PolarHBondContact N-O 3.22Å; H419-G432 PolarHBondContact O-N 2.85Å
420F98.3Very high96.4Very high99 Ų9981.5 Ų81.543%0.43444%0.435SS..EExtended strand (participates in β ladder)trans-131.6107.1177.3176.5-88.8000104.6S422 Y428 F431F420-S422 PolarHBondContact O-N 3.24Å; F420-Y428 HydrophobicContact CE2-CG 4.14Å; F420-Y428 HydrophobicContact CZ-CG 4.25Å; F420-F431 HydrophobicContact CD2-CB 4.32Å
421N98.1Very high96.5Very high49 Ų4981.8 Ų81.826%0.26244%0.435SS..EExtended strand (participates in β ladder)trans-90.191.2-177-165.4-113.5000107.8H419 Y428 N429 F430H419-N421 PolarHBondContact NE2-ND2 3.44Å; N421-Y428 CarbonylContact O-C 3.6Å; N421-Y428 WeakPolarHBondContact O-CA 3.2Å; N421-N429 HydrophobicContact CB-CB 4.39Å; N421-N429 PolarHBondContact O-N 3.15Å; N421-N429 VanDerWaalsContact OD1-CB 3.3Å; N421-N429 WeakPolarHBondContact OD1-CB 3.09Å; N421-N429 PolarHBondContact OD1-ND2 2.77Å; N421-F430 HydrophobicContact CB-CD1 3.66Å; N421-F430 HydrophobicContact CB-CD2 4.48Å; N421-F430 HydrophobicContact CB-CE1 3.47Å; N421-F430 VanDerWaalsContact CB-CE1 3.47Å; N421-F430 HydrophobicContact CB-CE2 4.32Å; N421-F430 HydrophobicContact CB-CG 4.17Å; N421-F430 HydrophobicContact CB-CZ 3.83Å; N421-F430 PolarHBondContact N-O 3.46Å
422S97.6Very high96.7Very high30 Ų3079.7 Ų79.721%0.2142%0.424CS..EExtended strand (participates in β ladder)trans-64.2145.8174.6-175.40000110.3F420 F424 G427F420-S422 PolarHBondContact O-N 3.24Å; S422-F424 VanDerWaalsContact C-N 3.26Å; S422-F424 PolarHBondContact OG-N 3.03Å; S422-G427 PolarHBondContact OG-O 3.16Å
423N96.3Very high96.8Very high58 Ų5878.3 Ų78.331%0.3142%0.417SS..  trans-86.8-1.1166.571.55.5000112.4K425 G427N423-K425 PolarHBondContact O-N 2.99Å; N423-K425 WeakPolarHBondContact OD1-CA 3.2Å; N423-K425 PolarHBondContact OD1-N 2.89Å; N423-G427 VanDerWaalsContact CG-C 3.46Å; N423-G427 PolarHBondContact N-O 2.58Å; N423-G427 VanDerWaalsContact N-O 3.13Å; N423-G427 VanDerWaalsContact OD1-C 3.24Å; N423-G427 WeakPolarHBondContact OD1-CA 3.33Å; N423-G427 PolarHBondContact OD1-N 2.86Å; N423-G427 PolarHBondContact OD1-O 3.44Å; N423-G427 VanDerWaalsContact OD1-O 3.11Å
424F96.4Very high97.1Very high184 Ų18473.8 Ų73.881%0.80738%0.379SS*.SBendtrans59.721.4-176.9-52.5-79.1000115.1S422S422-F424 VanDerWaalsContact C-N 3.26Å; S422-F424 PolarHBondContact OG-N 3.03Å
425K96.4Very high97Very high189 Ų18972.9 Ų72.982%0.82237%0.373SS*.SBendtrans-127.629.4178.2-61.4-178.6-179.4-177.40112N423N423-K425 PolarHBondContact O-N 2.99Å; N423-K425 WeakPolarHBondContact OD1-CA 3.2Å; N423-K425 PolarHBondContact OD1-N 2.89Å
426G93.6Very high97Very high89 Ų8970.2 Ų70.292%0.91836%0.355SS*.SBendtrans818.9-175.700000115
427G93.4Very high96.9Very high23 Ų2369.2 Ų69.224%0.23735%0.351CS..SBendtrans-131.9-163176.100000113.5S422 N423S422-G427 PolarHBondContact OG-O 3.16Å; N423-G427 VanDerWaalsContact CG-C 3.46Å; N423-G427 PolarHBondContact N-O 2.58Å; N423-G427 VanDerWaalsContact N-O 3.13Å; N423-G427 VanDerWaalsContact OD1-C 3.24Å; N423-G427 WeakPolarHBondContact OD1-CA 3.33Å; N423-G427 PolarHBondContact OD1-N 2.86Å; N423-G427 PolarHBondContact OD1-O 3.44Å; N423-G427 VanDerWaalsContact OD1-O 3.11Å
428Y96.6Very high96.9Very high50 Ų5066.1 Ų66.120%0.19634%0.339CS..EExtended strand (participates in β ladder)trans-143.8151.8-17769.9-72.5000111.1F420 N421 V706 P708 P714F420-Y428 HydrophobicContact CE2-CG 4.14Å; F420-Y428 HydrophobicContact CZ-CG 4.25Å; N421-Y428 CarbonylContact O-C 3.6Å; N421-Y428 WeakPolarHBondContact O-CA 3.2Å; Y428-V706 HydrophobicContact CE2-CG1 4.21Å; Y428-P708 HydrophobicContact CE1-CG 4.43Å; Y428-P708 HydrophobicContact CE2-CG 4.25Å; Y428-P708 WeakPolarHBondContact O-CG 3.41Å; Y428-P714 WeakPolarHBondContact OH-CB 3.24Å
429N97Very high96.9Very high82 Ų8259.7 Ų59.744%0.43932%0.315SS..EExtended strand (participates in β ladder)trans-88-41171.1-57.7-39.1000110.6N421 P708N421-N429 HydrophobicContact CB-CB 4.39Å; N421-N429 PolarHBondContact O-N 3.15Å; N421-N429 VanDerWaalsContact OD1-CB 3.3Å; N421-N429 WeakPolarHBondContact OD1-CB 3.09Å; N421-N429 PolarHBondContact OD1-ND2 2.77Å; N429-P708 WeakPolarHBondContact O-CD 3.37Å
430F98Very high96.9Very high73 Ų7355.3 Ų55.332%0.3229%0.294SS..EExtended strand (participates in β ladder)trans-163.6158.3170.168.5-86.7000112.6H419 N421 V706 R707H419-F430 AromaticContact CD2-CZ 3.95Å; N421-F430 HydrophobicContact CB-CD1 3.66Å; N421-F430 HydrophobicContact CB-CD2 4.48Å; N421-F430 HydrophobicContact CB-CE1 3.47Å; N421-F430 VanDerWaalsContact CB-CE1 3.47Å; N421-F430 HydrophobicContact CB-CE2 4.32Å; N421-F430 HydrophobicContact CB-CG 4.17Å; N421-F430 HydrophobicContact CB-CZ 3.83Å; N421-F430 PolarHBondContact N-O 3.46Å; F430-V706 CarbonylContact C-O 3.58Å; F430-V706 WeakPolarHBondContact CA-O 3.25Å; F430-V706 WeakPolarHBondContact CB-O 3.44Å; F430-R707 HydrophobicContact CB-CG 3.96Å
431F98.4Very high97Very high68 Ų6850.6 Ų50.630%0.29827%0.274SS..EExtended strand (participates in β ladder)trans-110142.8157.9165.4-92.9000108.9H419 F420 I705 V706H419-F431 WeakPolarHBondContact O-CA 3.47Å; H419-F431 WeakPolarHBondContact O-CD2 3.25Å; F420-F431 HydrophobicContact CD2-CB 4.32Å; F431-I705 CarbonylContact O-C 3.38Å; F431-I705 VanDerWaalsContact O-CA 3.29Å; F431-I705 WeakPolarHBondContact O-CA 3.23Å; F431-I705 WeakPolarHBondContact O-CG2 3.31Å; F431-V706 HydrophobicContact CB-CB 4.28Å; F431-V706 HydrophobicContact CD1-CG2 4.12Å; F431-V706 PolarHBondContact N-O 2.93Å; F431-V706 PolarHBondContact O-N 3.49Å
432G98.3Very high97Very high11 Ų1150.4 Ų50.411%0.11327%0.269CS..EExtended strand (participates in β ladder)trans-136.6135.9170.800000110.3R418 H419 V704R418-G432 CarbonylContact C-O 3.58Å; R418-G432 WeakPolarHBondContact CA-O 3.3Å; H419-G432 PolarHBondContact N-O 3.22Å; H419-G432 PolarHBondContact O-N 2.85Å; G432-V704 WeakPolarHBondContact CA-O 3.42Å
433G97.9Very high97.1Very high9 Ų949 Ų499%0.09326%0.259CS..EExtended strand (participates in β ladder)trans-149.3149.1-179.900000112.1R417 V704R417-G433 WeakPolarHBondContact O-CA 3.45Å; G433-V704 PolarHBondContact N-O 2.97Å; G433-V704 PolarHBondContact O-N 3.23Å
434L97.4Very high97.2Very high4 Ų446.8 Ų46.82%0.02125%0.248CC..EExtended strand (participates in β ladder)trans-133.4125.2170.9175.758.7000108P415 L416 R417P415-L434 CarbonylContact C-O 3.58Å; P415-L434 VanDerWaalsContact CA-O 3.28Å; P415-L434 WeakPolarHBondContact CA-O 3.35Å; P415-L434 WeakPolarHBondContact CB-O 3.23Å; L416-L434 HydrophobicContact CB-CG 4.36Å; L416-L434 HydrophobicContact CD2-CD2 3.84Å; L416-L434 HydrophobicContact CD2-CG 4.4Å; L416-L434 PolarHBondContact N-O 3.27Å; R417-L434 HydrophobicContact CG-CB 4Å; R417-L434 PolarHBondContact O-N 3.06Å
435E94.3Very high97.3Very high111 Ų11138 Ų3852%0.51921%0.21SC..EExtended strand (participates in β ladder)trans-63.6145.2173-177171.7-135.400110.9T411 T437T411-E435 HydrophobicContact CG2-CG 4.3Å; T411-E435 WeakPolarHBondContact CG2-OE1 3.24Å; E435-T437 HydrophobicContact CG-CG2 4.25Å
436N96.3Very high97.4Very high15 Ų1530.3 Ų30.38%0.0818%0.178CC..EExtended strand (participates in β ladder)trans-93.9105.4174.8-166.420.5000110.3T411 T412 M414 L416T411-N436 WeakPolarHBondContact CA-O 3.4Å; T412-N436 HydrophobicContact CG2-CB 4.26Å; T412-N436 VanDerWaalsContact CG2-ND2 3.34Å; T412-N436 WeakPolarHBondContact CG2-ND2 3.39Å; T412-N436 PolarHBondContact N-O 3.05Å; T412-N436 WeakPolarHBondContact OG1-CB 3.2Å; T412-N436 PolarHBondContact OG1-ND2 2.86Å; M414-N436 WeakPolarHBondContact O-CB 3.26Å; M414-N436 PolarHBondContact O-N 3.18Å; L416-N436 HydrophobicContact CB-CB 3.92Å
437T95.5Very high97.4Very high16 Ų1627.2 Ų27.210%0.09814%0.142CC..EExtended strand (participates in β ladder)trans-109135.3170.564.40000109.8R298 Y308 E409 M410 T411 E435 P460R298-T437 PolarHBondContact NH2-OG1 3.18Å; Y308-T437 PolarHBondContact OH-O 3.31Å; Y308-T437 VanDerWaalsContact OH-O 3.1Å; Y308-T437 PolarHBondContact OH-OG1 3.44Å; E409-T437 VanDerWaalsContact OE1-CB 3.24Å; E409-T437 WeakPolarHBondContact OE1-CB 3.48Å; E409-T437 PolarHBondContact OE1-OG1 2.93Å; M410-T437 CarbonylContact O-C 3.57Å; M410-T437 WeakPolarHBondContact O-CA 3.3Å; T411-T437 HydrophobicContact CG2-CG2 3.96Å; E435-T437 HydrophobicContact CG-CG2 4.25Å; T437-P460 WeakPolarHBondContact O-CD 3.46Å; T437-P460 WeakPolarHBondContact O-CG 3.17Å
438V98.1Very high97.4Very high0 Ų029.7 Ų29.70%014%0.144CC..EExtended strand (participates in β ladder)trans-126.4142.1-178.3-61.70000109.8E409 M410 T412 V440 L457 Y459E409-V438 CarbonylContact C-O 3.49Å; E409-V438 WeakPolarHBondContact CA-O 3.26Å; M410-V438 HydrophobicContact CG-CG2 3.61Å; M410-V438 PolarHBondContact N-O 3.39Å; M410-V438 PolarHBondContact O-N 2.88Å; M410-V438 HydrophobicContact SD-CG2 4.42Å; T412-V438 HydrophobicContact CG2-CB 4.46Å; T412-V438 HydrophobicContact CG2-CG1 3.72Å; T412-V438 HydrophobicContact CG2-CG2 3.87Å; V438-V440 HydrophobicContact CG2-CG2 4.21Å; V438-L457 HydrophobicContact CG2-CD2 4.3Å; V438-Y459 HydrophobicContact CG1-CD1 3.34Å; V438-Y459 HydrophobicContact CG1-CD2 4.21Å; V438-Y459 HydrophobicContact CG1-CE1 3.42Å; V438-Y459 VanDerWaalsContact CG1-CE1 3.42Å; V438-Y459 HydrophobicContact CG1-CE2 4.27Å; V438-Y459 HydrophobicContact CG1-CG 3.76Å
439L98.8Very high97.4Very high0 Ų027.8 Ų27.80%014%0.138CC..EExtended strand (participates in β ladder)trans-86.6135.8165.8-176.482.7000108.7Y299 V306 Y308 F313 I407 F408 L457 F458Y299-L439 HydrophobicContact CD1-CD1 3.63Å; Y299-L439 HydrophobicContact CD2-CD1 4.23Å; Y299-L439 HydrophobicContact CE1-CD1 4.26Å; Y299-L439 HydrophobicContact CG-CD1 3.63Å; V306-L439 HydrophobicContact CG1-CD2 3.75Å; Y308-L439 HydrophobicContact CD1-CB 3.35Å; Y308-L439 HydrophobicContact CD1-CD2 4.18Å; Y308-L439 HydrophobicContact CD1-CG 4.27Å; Y308-L439 HydrophobicContact CD2-CB 4.35Å; Y308-L439 HydrophobicContact CE1-CB 3.61Å; Y308-L439 HydrophobicContact CG-CB 3.76Å; Y308-L439 HydrophobicContact CG-CD1 4.32Å; Y308-L439 HydrophobicContact CG-CD2 4.09Å; Y308-L439 HydrophobicContact CG-CG 4.28Å; F313-L439 HydrophobicContact CE1-CD2 4.06Å; F313-L439 HydrophobicContact CZ-CD2 4.06Å; I407-L439 HydrophobicContact CG2-CD1 3.88Å; I407-L439 HydrophobicContact CG2-CG 4.36Å; F408-L439 CarbonylContact O-C 3.56Å; F408-L439 WeakPolarHBondContact O-CA 3.27Å; L439-L457 CarbonylContact O-C 3.51Å; L439-L457 VanDerWaalsContact O-CA 3.3Å; L439-L457 WeakPolarHBondContact O-CA 3.46Å; L439-F458 HydrophobicContact CB-CB 4.31Å; L439-F458 HydrophobicContact CB-CD2 4.36Å; L439-F458 HydrophobicContact CD2-CD2 4.07Å; L439-F458 HydrophobicContact CG-CD2 4.47Å; L439-F458 PolarHBondContact N-O 3.25Å; L439-F458 PolarHBondContact O-N 3.09Å
440V98.9Very high97.4Very high1 Ų124.2 Ų24.21%0.00612%0.118CC..EExtended strand (participates in β ladder)trans-117.3130.4177.1-173.20000109.2I407 F408 M410 V438 R442 F456 L457I407-V440 WeakPolarHBondContact CA-O 3.2Å; F408-V440 HydrophobicContact CD1-CB 4.18Å; F408-V440 HydrophobicContact CD2-CB 4.25Å; F408-V440 HydrophobicContact CD2-CG2 4.32Å; F408-V440 HydrophobicContact CE1-CB 3.75Å; F408-V440 HydrophobicContact CE1-CG1 3.78Å; F408-V440 HydrophobicContact CE2-CB 3.84Å; F408-V440 HydrophobicContact CE2-CG1 4.4Å; F408-V440 HydrophobicContact CE2-CG2 3.74Å; F408-V440 HydrophobicContact CG-CB 4.42Å; F408-V440 HydrophobicContact CZ-CB 3.57Å; F408-V440 HydrophobicContact CZ-CG1 3.67Å; F408-V440 HydrophobicContact CZ-CG2 3.86Å; F408-V440 PolarHBondContact N-O 3.14Å; F408-V440 VanDerWaalsContact N-O 3.07Å; F408-V440 PolarHBondContact O-N 2.84Å; M410-V440 HydrophobicContact CG-CG2 4.05Å; M410-V440 HydrophobicContact SD-CG2 4.09Å; V438-V440 HydrophobicContact CG2-CG2 4.21Å; V440-R442 HydrophobicContact CG1-CB 4.27Å; V440-F456 WeakPolarHBondContact CA-O 3.32Å; V440-L457 HydrophobicContact CG2-CD2 4.18Å; V440-L457 HydrophobicContact CG2-CG 4.14Å
441L98.9Very high97.4Very high0 Ų022.8 Ų22.80%011%0.114CC..EExtended strand (participates in β ladder)trans-109.4117.2165.4174.274000107.1F313 Y315 L323 V325 L405 I407 F456 F458F313-L441 HydrophobicContact CE2-CD2 4.13Å; Y315-L441 HydrophobicContact CD1-CD1 4.37Å; Y315-L441 HydrophobicContact CD2-CD1 4.39Å; Y315-L441 HydrophobicContact CG-CD1 4.23Å; Y315-L441 HydrophobicContact CG-CD2 4.24Å; L323-L441 HydrophobicContact CD1-CD2 4.03Å; L323-L441 HydrophobicContact CD1-CG 4.3Å; L323-L441 HydrophobicContact CD2-CD2 4.35Å; L323-L441 HydrophobicContact CD2-CG 4.31Å; L323-L441 HydrophobicContact CG-CD2 4.46Å; V325-L441 HydrophobicContact CG2-CD2 3.9Å; L405-L441 HydrophobicContact CD1-CD1 3.93Å; L405-L441 HydrophobicContact CD2-CD1 3.77Å; L405-L441 HydrophobicContact CG-CD1 4.08Å; I407-L441 HydrophobicContact CD1-CD1 3.9Å; I407-L441 HydrophobicContact CG1-CD1 3.5Å; I407-L441 VanDerWaalsContact CG1-CD1 3.5Å; L441-F456 HydrophobicContact CB-CB 4.33Å; L441-F456 HydrophobicContact CD2-CD2 4.44Å; L441-F456 PolarHBondContact N-O 3.14Å; L441-F456 PolarHBondContact O-N 3.14Å; L441-F458 HydrophobicContact CB-CE2 4.2Å
442R98.9Very high97.4Very high45 Ų4519.8 Ų19.817%0.1710%0.101CC..EExtended strand (participates in β ladder)trans-129.3139.7-173.7170.6176.7-66.5175.9-2.9112.5D379 L405 C406 V440 I453 W454 D455D379-R442 WeakPolarHBondContact O-CD 3.35Å; D379-R442 PolarHBondContact O-NH1 3.42Å; L405-R442 CarbonylContact C-O 3.58Å; L405-R442 WeakPolarHBondContact CA-O 3.46Å; L405-R442 WeakPolarHBondContact CG-O 3.48Å; C406-R442 PolarHBondContact N-O 2.83Å; C406-R442 PolarHBondContact O-N 2.96Å; V440-R442 HydrophobicContact CG1-CB 4.27Å; R442-I453 HydrophobicContact CG-CG2 3.99Å; R442-W454 VanDerWaalsContact CA-O 3.32Å; R442-W454 WeakPolarHBondContact CA-O 3.38Å; R442-D455 WeakPolarHBondContact CB-OD1 3.14Å; R442-D455 IonicContact CZ-OD1 2.71Å; R442-D455 IonicContact CZ-OD2 3.19Å; R442-D455 IonicContact NE-OD1 2.64Å; R442-D455 PolarHBondContact NE-OD1 2.8Å; R442-D455 IonicContact NE-OD2 3.85Å; R442-D455 VanDerWaalsContact NH2-CG 3.34Å; R442-D455 IonicContact NH2-OD1 3.31Å; R442-D455 PolarHBondContact NH2-OD1 2.77Å; R442-D455 VanDerWaalsContact NH2-OD1 3.14Å; R442-D455 IonicContact NH2-OD2 2.76Å; R442-D455 PolarHBondContact NH2-OD2 3.47Å
443T98.9Very high97.5Very high0 Ų020.5 Ų20.50%010%0.102CC..EExtended strand (participates in β ladder)trans-138.9167.5163.5-1640000108.6L323 T371 A404 W454L323-T443 HydrophobicContact CB-CG2 3.78Å; L323-T443 HydrophobicContact CD1-CG2 4.24Å; L323-T443 HydrophobicContact CD2-CG2 4.08Å; L323-T443 HydrophobicContact CG-CG2 4.26Å; T371-T443 WeakPolarHBondContact CG2-OG1 3.22Å; A404-T443 PolarHBondContact O-OG1 3.19Å; T443-W454 HydrophobicContact CG2-CB 4.13Å; T443-W454 HydrophobicContact CG2-CG 4.39Å; T443-W454 PolarHBondContact N-O 3.18Å; T443-W454 PolarHBondContact O-N 2.78Å
444T98.8Very high97.5Very high13 Ų1320.2 Ų20.28%0.0810%0.098CC..EExtended strand (participates in β ladder)trans-118.1163.617353.40000112.1T371 L374 Y452 I453T371-T444 VanDerWaalsContact CA-O 3.29Å; T371-T444 WeakPolarHBondContact CA-O 3.33Å; T371-T444 WeakPolarHBondContact CB-O 3.32Å; T371-T444 WeakPolarHBondContact CG2-O 3.47Å; L374-T444 HydrophobicContact CD2-CG2 3.55Å; T444-Y452 CarbonylContact C-O 3.55Å; T444-Y452 WeakPolarHBondContact CA-O 3.33Å; T444-Y452 WeakPolarHBondContact CB-O 3.4Å; T444-I453 HydrophobicContact CG2-CG1 4.16Å
445S98.6Very high97.6Very high0 Ų020.1 Ų20.10%010%0.097CC..EExtended strand (participates in β ladder)trans-133.5107163.9-66.60000109.1M367 S370 Y452 W454M367-S445 WeakPolarHBondContact O-CB 3.21Å; M367-S445 PolarHBondContact O-OG 2.96Å; S370-S445 WeakPolarHBondContact O-CA 3.3Å; S445-Y452 PolarHBondContact N-O 3.43Å; S445-Y452 PolarHBondContact O-N 3.32Å; S445-W454 PolarHBondContact OG-NE1 2.61Å
446T98.4Very high97.8Very high26 Ų2615 Ų1516%0.167%0.074CC..EExtended strand (participates in β ladder)trans-99.378.3172.8-43.70000108.6S370 Y372 Y448 Y450 D451S370-T446 WeakPolarHBondContact CB-O 3.47Å; S370-T446 PolarHBondContact O-N 2.93Å; Y372-T446 WeakPolarHBondContact CE2-O 3.11Å; T446-Y448 VanDerWaalsContact C-N 3.31Å; T446-Y448 PolarHBondContact O-N 2.69Å; T446-Y450 WeakPolarHBondContact CA-O 3.44Å; T446-D451 WeakPolarHBondContact CB-OD1 3.27Å; T446-D451 WeakPolarHBondContact CG2-OD1 3.49Å; T446-D451 PolarHBondContact OG1-OD1 3.15Å
447V93.1Very high97.9Very high25 Ų2514.7 Ų14.715%0.1527%0.072CC..  trans-62.4-44.3-172.3-178.50000110.6D362 W365 M367D362-V447 HydrophobicContact CB-CG2 4.21Å; W365-V447 HydrophobicContact CB-CG1 3.64Å; W365-V447 HydrophobicContact CG-CG1 3.89Å; M367-V447 HydrophobicContact CB-CG2 3.66Å
448Y95.1Very high98.1Very high74 Ų7414 Ų1429%0.297%0.067SC..SBendtrans-154.6-88.4176.3-178-121.1000109.8F183 S184 Y209 F210 T446F183-Y448 PolarHBondContact O-OH 3.07Å; S184-Y448 PolarHBondContact OG-OH 3.15Å; Y209-Y448 HydrophobicContact CE2-CE2 4.5Å; Y209-Y448 AromaticContact CE2-CZ 3.97Å; Y209-Y448 WeakPolarHBondContact CE2-OH 3.48Å; Y209-Y448 WeakPolarHBondContact OH-CE2 3.32Å; Y209-Y448 PolarHBondContact OH-OH 3.09Å; F210-Y448 HydrophobicContact CD1-CD1 4.05Å; F210-Y448 AromaticContact CD1-CE1 3.55Å; F210-Y448 HydrophobicContact CD1-CE1 3.55Å; F210-Y448 HydrophobicContact CD1-CE2 4.46Å; F210-Y448 AromaticContact CD1-CZ 3.81Å; F210-Y448 AromaticContact CE1-CD1 3.83Å; F210-Y448 HydrophobicContact CE1-CD1 3.83Å; F210-Y448 AromaticContact CE1-CD2 3.96Å; F210-Y448 HydrophobicContact CE1-CD2 3.96Å; F210-Y448 AromaticContact CE1-CE1 3.56Å; F210-Y448 HydrophobicContact CE1-CE1 3.56Å; F210-Y448 AromaticContact CE1-CE2 3.71Å; F210-Y448 HydrophobicContact CE1-CE2 3.71Å; F210-Y448 HydrophobicContact CE1-CG 4.03Å; F210-Y448 AromaticContact CE1-CZ 3.52Å; T446-Y448 VanDerWaalsContact C-N 3.31Å; T446-Y448 PolarHBondContact O-N 2.69Å
449N96.6Very high98.1Very high10 Ų1015.6 Ų15.65%0.0537%0.073CC..SBendtrans-90.4-34.2-178.263.6-65.1000113.4F210 Y473 H475F210-N449 HydrophobicContact CB-CB 4.34Å; F210-N449 HydrophobicContact CD1-CB 3.63Å; F210-N449 HydrophobicContact CD2-CB 4.38Å; F210-N449 HydrophobicContact CE1-CB 3.91Å; F210-N449 HydrophobicContact CG-CB 3.87Å; F210-N449 HydrophobicContact CZ-CB 4.4Å; N449-Y473 CarbonylContact C-O 3.49Å; N449-Y473 PolarHBondContact ND2-O 2.88Å; N449-Y473 PolarHBondContact O-N 3.42Å; N449-H475 PolarHBondContact ND2-N 3.14Å; N449-H475 VanDerWaalsContact ND2-N 3.19Å
450Y96.5Very high98.1Very high7 Ų716.4 Ų16.43%0.0278%0.079CC..EExtended strand (participates in β ladder)trans-86.4144.3177.1-84.4-82.5000112Y348 T446 A470 T471 H499 H501Y348-Y450 WeakPolarHBondContact OH-CE2 3.41Å; T446-Y450 WeakPolarHBondContact CA-O 3.44Å; Y450-A470 HydrophobicContact CD1-CB 4.44Å; Y450-T471 WeakPolarHBondContact CD1-O 3.31Å; Y450-H499 AromaticContact CZ-NE2 3.67Å; Y450-H499 PolarHBondContact OH-CE1 2.84Å; Y450-H499 PolarHBondContact OH-NE2 2.8Å; Y450-H501 AromaticContact CD1-CE1 3.91Å; Y450-H501 AromaticContact CE1-CE1 3.63Å; Y450-H501 AromaticContact CE1-NE2 3.68Å; Y450-H501 AromaticContact CZ-CE1 3.83Å; Y450-H501 AromaticContact CZ-NE2 3.85Å
451D98.4Very high98Very high44 Ų4418 Ų1824%0.2359%0.087CC..EExtended strand (participates in β ladder)trans-111111.1168.4-66-91.7000108.6T446 T471 G472T446-D451 WeakPolarHBondContact CB-OD1 3.27Å; T446-D451 WeakPolarHBondContact CG2-OD1 3.49Å; T446-D451 PolarHBondContact OG1-OD1 3.15Å; D451-T471 HydrophobicContact CB-CG2 3.67Å; D451-T471 PolarHBondContact N-O 2.92Å; D451-T471 PolarHBondContact O-N 3.27Å; D451-G472 VanDerWaalsContact OD2-CA 3.25Å; D451-G472 WeakPolarHBondContact OD2-CA 3.24Å
452Y98.8Very high98Very high4 Ų418 Ų182%0.0169%0.087CC..EExtended strand (participates in β ladder)trans-94.1129.1170.7-61.5-67.8000110.4D362 T444 S445 W454 V468 A470 H501D362-Y452 VanDerWaalsContact OD2-CE2 3.26Å; D362-Y452 WeakPolarHBondContact OD2-CE2 2.95Å; T444-Y452 CarbonylContact C-O 3.55Å; T444-Y452 WeakPolarHBondContact CA-O 3.33Å; T444-Y452 WeakPolarHBondContact CB-O 3.4Å; S445-Y452 PolarHBondContact N-O 3.43Å; S445-Y452 PolarHBondContact O-N 3.32Å; Y452-W454 VanDerWaalsContact CB-CE2 3.49Å; Y452-W454 HydrophobicContact CD1-CH2 4.44Å; Y452-W454 HydrophobicContact CD1-CZ2 4.48Å; Y452-W454 HydrophobicContact CD2-CH2 4.47Å; Y452-W454 AromaticContact CD2-CZ2 3.91Å; Y452-W454 HydrophobicContact CD2-CZ2 3.91Å; Y452-W454 HydrophobicContact CG-CH2 4.06Å; Y452-W454 AromaticContact CG-CZ2 3.67Å; Y452-W454 HydrophobicContact CG-CZ2 3.67Å; Y452-V468 HydrophobicContact CD1-CG2 4.17Å; Y452-A470 HydrophobicContact CD1-CB 4.17Å; Y452-A470 HydrophobicContact CE1-CB 4.16Å; Y452-H501 AromaticContact CE1-ND1 3.75Å; Y452-H501 AromaticContact CZ-ND1 3.93Å; Y452-H501 PolarHBondContact OH-ND1 3.03Å
453I98.9Very high98Very high26 Ų2616.3 Ų16.313%0.1338%0.082CC..EExtended strand (participates in β ladder)trans-101.9115.7173.8-52.9174000108.2R442 T444 V468 S469 T471 T677R442-I453 HydrophobicContact CG-CG2 3.99Å; T444-I453 HydrophobicContact CG2-CG1 4.16Å; I453-V468 VanDerWaalsContact O-CA 3.27Å; I453-V468 WeakPolarHBondContact O-CA 3.28Å; I453-S469 PolarHBondContact N-O 3Å; I453-S469 PolarHBondContact O-N 3.28Å; I453-T471 HydrophobicContact CD1-CG2 4.35Å; I453-T677 HydrophobicContact CD1-CG2 4.07Å
454W98.8Very high98Very high4 Ų416.3 Ų16.32%0.0158%0.082CC..EExtended strand (participates in β ladder)trans-103.7115.3-176.6-50.1106.5000110.7L323 L341 A344 M367 R442 T443 S445 Y452 V468 I503L323-W454 HydrophobicContact CD2-CB 4.3Å; L341-W454 HydrophobicContact CD1-CE3 4.39Å; L341-W454 HydrophobicContact CD1-CH2 4.07Å; L341-W454 HydrophobicContact CD1-CZ3 3.87Å; L341-W454 HydrophobicContact CD2-CD2 3.85Å; L341-W454 HydrophobicContact CD2-CE3 3.97Å; L341-W454 HydrophobicContact CD2-CH2 3.88Å; L341-W454 HydrophobicContact CD2-CZ2 3.72Å; L341-W454 HydrophobicContact CD2-CZ3 3.98Å; A344-W454 HydrophobicContact CB-CH2 4Å; A344-W454 HydrophobicContact CB-CZ2 4.46Å; M367-W454 HydrophobicContact SD-CZ2 4.06Å; R442-W454 VanDerWaalsContact CA-O 3.32Å; R442-W454 WeakPolarHBondContact CA-O 3.38Å; T443-W454 HydrophobicContact CG2-CB 4.13Å; T443-W454 HydrophobicContact CG2-CG 4.39Å; T443-W454 PolarHBondContact N-O 3.18Å; T443-W454 PolarHBondContact O-N 2.78Å; S445-W454 PolarHBondContact OG-NE1 2.61Å; Y452-W454 VanDerWaalsContact CB-CE2 3.49Å; Y452-W454 HydrophobicContact CD1-CH2 4.44Å; Y452-W454 HydrophobicContact CD1-CZ2 4.48Å; Y452-W454 HydrophobicContact CD2-CH2 4.47Å; Y452-W454 AromaticContact CD2-CZ2 3.91Å; Y452-W454 HydrophobicContact CD2-CZ2 3.91Å; Y452-W454 HydrophobicContact CG-CH2 4.06Å; Y452-W454 AromaticContact CG-CZ2 3.67Å; Y452-W454 HydrophobicContact CG-CZ2 3.67Å; W454-V468 HydrophobicContact CD2-CG2 4.32Å; W454-V468 HydrophobicContact CE3-CB 3.67Å; W454-V468 HydrophobicContact CE3-CG2 3.54Å; W454-V468 HydrophobicContact CH2-CG2 3.81Å; W454-V468 HydrophobicContact CZ3-CB 3.55Å; W454-V468 HydrophobicContact CZ3-CG1 4.27Å; W454-V468 HydrophobicContact CZ3-CG2 3.23Å; W454-I503 HydrophobicContact CH2-CG1 4.26Å; W454-I503 HydrophobicContact CH2-CG2 4.19Å; W454-I503 HydrophobicContact CZ3-CG1 4.26Å; W454-I503 HydrophobicContact CZ3-CG2 3.77Å
455D98.9Very high98Very high2 Ų216.6 Ų16.61%0.0118%0.082CC..EExtended strand (participates in β ladder)trans-116.6135-178.4-71.1-15.8000112.4R442 L457 K467R442-D455 WeakPolarHBondContact CB-OD1 3.14Å; R442-D455 IonicContact CZ-OD1 2.71Å; R442-D455 IonicContact CZ-OD2 3.19Å; R442-D455 IonicContact NE-OD1 2.64Å; R442-D455 PolarHBondContact NE-OD1 2.8Å; R442-D455 IonicContact NE-OD2 3.85Å; R442-D455 VanDerWaalsContact NH2-CG 3.34Å; R442-D455 IonicContact NH2-OD1 3.31Å; R442-D455 PolarHBondContact NH2-OD1 2.77Å; R442-D455 VanDerWaalsContact NH2-OD1 3.14Å; R442-D455 IonicContact NH2-OD2 2.76Å; R442-D455 PolarHBondContact NH2-OD2 3.47Å; D455-L457 HydrophobicContact CB-CD1 3.63Å; D455-K467 HydrophobicContact CB-CB 4.23Å; D455-K467 PolarHBondContact N-O 3.32Å; D455-K467 PolarHBondContact O-N 2.93Å; D455-K467 WeakPolarHBondContact OD2-CE 3.49Å; D455-K467 IonicContact OD2-NZ 2.78Å; D455-K467 PolarHBondContact OD2-NZ 3.32Å; D455-K467 VanDerWaalsContact OD2-NZ 3.16Å
456F98.9Very high98Very high4 Ų416.6 Ų16.62%0.0188%0.083CC..EExtended strand (participates in β ladder)trans-107.8124.3151.2-73.2-89.8000109.4L323 V325 I339 V440 L441 F458 V464 E465 V466L323-F456 HydrophobicContact CB-CE2 4.44Å; L323-F456 HydrophobicContact CD2-CD2 3.6Å; L323-F456 HydrophobicContact CD2-CE2 3.9Å; L323-F456 HydrophobicContact CG-CD2 3.98Å; L323-F456 HydrophobicContact CG-CE2 3.85Å; V325-F456 HydrophobicContact CB-CE1 4.45Å; V325-F456 HydrophobicContact CB-CZ 4.49Å; V325-F456 HydrophobicContact CG2-CB 4.44Å; V325-F456 HydrophobicContact CG2-CD1 3.97Å; V325-F456 HydrophobicContact CG2-CD2 3.73Å; V325-F456 HydrophobicContact CG2-CE1 4.1Å; V325-F456 HydrophobicContact CG2-CE2 3.88Å; V325-F456 HydrophobicContact CG2-CG 3.79Å; V325-F456 HydrophobicContact CG2-CZ 4.05Å; I339-F456 HydrophobicContact CB-CE1 3.83Å; I339-F456 HydrophobicContact CB-CZ 4.18Å; I339-F456 HydrophobicContact CD1-CE1 4.48Å; I339-F456 HydrophobicContact CG2-CE1 3.58Å; I339-F456 HydrophobicContact CG2-CZ 3.95Å; V440-F456 WeakPolarHBondContact CA-O 3.32Å; L441-F456 HydrophobicContact CB-CB 4.33Å; L441-F456 HydrophobicContact CD2-CD2 4.44Å; L441-F456 PolarHBondContact N-O 3.14Å; L441-F456 PolarHBondContact O-N 3.14Å; F456-F458 HydrophobicContact CB-CE2 3.74Å; F456-F458 HydrophobicContact CB-CZ 3.7Å; F456-F458 HydrophobicContact CG-CZ 4.44Å; F456-V464 HydrophobicContact CD1-CG1 4.3Å; F456-E465 CarbonylContact C-O 3.47Å; F456-E465 WeakPolarHBondContact CA-O 3.24Å; F456-V466 HydrophobicContact CD1-CG2 3.75Å; F456-V466 HydrophobicContact CE1-CB 4.36Å; F456-V466 HydrophobicContact CE1-CG1 4.09Å; F456-V466 HydrophobicContact CE1-CG2 3.5Å; F456-V466 HydrophobicContact CZ-CG1 4.29Å; F456-V466 HydrophobicContact CZ-CG2 4.45Å
457L98.9Very high98Very high8 Ų817.2 Ų17.24%0.0428%0.083CC..EExtended strand (participates in β ladder)trans-112.5130.2175.1-51.783.9000110.7V438 L439 V440 D455 Y459 V464 E465 K467V438-L457 HydrophobicContact CG2-CD2 4.3Å; L439-L457 CarbonylContact O-C 3.51Å; L439-L457 VanDerWaalsContact O-CA 3.3Å; L439-L457 WeakPolarHBondContact O-CA 3.46Å; V440-L457 HydrophobicContact CG2-CD2 4.18Å; V440-L457 HydrophobicContact CG2-CG 4.14Å; D455-L457 HydrophobicContact CB-CD1 3.63Å; L457-Y459 HydrophobicContact CB-CE2 4Å; L457-V464 CarbonylContact O-C 3.58Å; L457-V464 WeakPolarHBondContact O-CA 3.35Å; L457-E465 HydrophobicContact CB-CB 4.15Å; L457-E465 HydrophobicContact CD1-CB 4.12Å; L457-E465 HydrophobicContact CD1-CG 4.04Å; L457-E465 PolarHBondContact N-O 2.89Å; L457-E465 PolarHBondContact O-N 3.24Å; L457-K467 HydrophobicContact CD1-CB 4.24Å
458F98.9Very high98.3Very high0 Ų016.2 Ų16.20%08%0.077CC..EExtended strand (participates in β ladder)trans-113.7111.2-176-54.1-87.2000110.2W311 F313 V325 L328 L439 L441 F456 V464W311-F458 HydrophobicContact CD2-CB 4.09Å; W311-F458 HydrophobicContact CD2-CD1 4.07Å; W311-F458 HydrophobicContact CE3-CD1 4.16Å; W311-F458 HydrophobicContact CG-CB 3.97Å; W311-F458 HydrophobicContact CG-CD1 4.44Å; F313-F458 HydrophobicContact CD1-CD1 4.36Å; F313-F458 AromaticContact CD1-CE1 3.92Å; F313-F458 HydrophobicContact CD1-CE1 3.92Å; F313-F458 HydrophobicContact CD1-CE2 4.41Å; F313-F458 AromaticContact CD1-CZ 3.94Å; F313-F458 HydrophobicContact CD1-CZ 3.94Å; F313-F458 HydrophobicContact CD2-CZ 4.31Å; F313-F458 HydrophobicContact CE1-CD1 4.13Å; F313-F458 AromaticContact CE1-CD2 3.88Å; F313-F458 HydrophobicContact CE1-CD2 3.88Å; F313-F458 AromaticContact CE1-CE1 3.84Å; F313-F458 HydrophobicContact CE1-CE1 3.84Å; F313-F458 AromaticContact CE1-CE2 3.57Å; F313-F458 HydrophobicContact CE1-CE2 3.57Å; F313-F458 HydrophobicContact CE1-CG 4.14Å; F313-F458 AromaticContact CE1-CZ 3.54Å; F313-F458 HydrophobicContact CE1-CZ 3.54Å; F313-F458 HydrophobicContact CE2-CE2 4.12Å; F313-F458 AromaticContact CE2-CZ 3.95Å; F313-F458 HydrophobicContact CE2-CZ 3.95Å; F313-F458 HydrophobicContact CG-CE1 4.46Å; F313-F458 HydrophobicContact CG-CZ 4.31Å; F313-F458 HydrophobicContact CZ-CD2 4.03Å; F313-F458 HydrophobicContact CZ-CE1 4.31Å; F313-F458 AromaticContact CZ-CE2 3.38Å; F313-F458 HydrophobicContact CZ-CE2 3.38Å; F313-F458 AromaticContact CZ-CZ 3.54Å; F313-F458 HydrophobicContact CZ-CZ 3.54Å; V325-F458 HydrophobicContact CG1-CZ 4.49Å; V325-F458 HydrophobicContact CG2-CZ 4.27Å; L328-F458 HydrophobicContact CD1-CD1 4.07Å; L328-F458 HydrophobicContact CD1-CE1 3.64Å; L439-F458 HydrophobicContact CB-CB 4.31Å; L439-F458 HydrophobicContact CB-CD2 4.36Å; L439-F458 HydrophobicContact CD2-CD2 4.07Å; L439-F458 HydrophobicContact CG-CD2 4.47Å; L439-F458 PolarHBondContact N-O 3.25Å; L439-F458 PolarHBondContact O-N 3.09Å; L441-F458 HydrophobicContact CB-CE2 4.2Å; F456-F458 HydrophobicContact CB-CE2 3.74Å; F456-F458 HydrophobicContact CB-CZ 3.7Å; F456-F458 HydrophobicContact CG-CZ 4.44Å; F458-V464 HydrophobicContact CD1-CG1 4.28Å; F458-V464 HydrophobicContact CD1-CG2 3.81Å; F458-V464 HydrophobicContact CE1-CG1 4.18Å; F458-V464 HydrophobicContact CE1-CG2 4.19Å
459Y98.7Very high98.4Very high34 Ų3413.2 Ų13.213%0.1337%0.067CC..  trans-92.1148.6-175.4-67.9-104.9000111.8W311 V438 L457 N461 G462 V463 E465 F685W311-Y459 WeakPolarHBondContact CZ2-O 3.22Å; W311-Y459 PolarHBondContact NE1-O 2.97Å; V438-Y459 HydrophobicContact CG1-CD1 3.34Å; V438-Y459 HydrophobicContact CG1-CD2 4.21Å; V438-Y459 HydrophobicContact CG1-CE1 3.42Å; V438-Y459 VanDerWaalsContact CG1-CE1 3.42Å; V438-Y459 HydrophobicContact CG1-CE2 4.27Å; V438-Y459 HydrophobicContact CG1-CG 3.76Å; L457-Y459 HydrophobicContact CB-CE2 4Å; Y459-N461 VanDerWaalsContact CB-OD1 3.26Å; Y459-N461 WeakPolarHBondContact CB-OD1 3.33Å; Y459-N461 PolarHBondContact O-N 2.85Å; Y459-G462 PolarHBondContact O-N 3.49Å; Y459-G462 VanDerWaalsContact O-N 3.15Å; Y459-V463 WeakPolarHBondContact CB-O 3.28Å; Y459-V463 HydrophobicContact CD2-CB 4.22Å; Y459-V463 HydrophobicContact CD2-CG1 4.01Å; Y459-V463 WeakPolarHBondContact CD2-O 3.11Å; Y459-V463 HydrophobicContact CG-CB 4.27Å; Y459-V463 HydrophobicContact CG-CG1 4.46Å; Y459-V463 PolarHBondContact N-O 3.43Å; Y459-E465 HydrophobicContact CE2-CB 3.79Å; Y459-E465 WeakPolarHBondContact CE2-OE2 3.24Å; Y459-E465 PolarHBondContact OH-OE2 3.29Å; Y459-F685 HydrophobicContact CE2-CE1 4.44Å
460P97.3Very high98.5Very high18 Ų1812.9 Ų12.912%0.1177%0.065CC..THydrogen-bonded Turntrans-68.2-12.2-175.7-20.334.3000114.4F330 L416 T437 G462F330-P460 WeakPolarHBondContact CZ-O 2.95Å; L416-P460 HydrophobicContact CD2-CB 4.26Å; L416-P460 HydrophobicContact CD2-CG 4.46Å; T437-P460 WeakPolarHBondContact O-CD 3.46Å; T437-P460 WeakPolarHBondContact O-CG 3.17Å; P460-G462 VanDerWaalsContact C-N 3.35Å
461N98.2Very high98.6Very high34 Ų3414 Ų1418%0.1827%0.073CC..THydrogen-bonded Turntrans-92.813.8176.967.9-12.2000113.6L416 Y459 V463 P696L416-N461 HydrophobicContact CD1-CB 4.36Å; L416-N461 HydrophobicContact CD2-CB 4.27Å; Y459-N461 VanDerWaalsContact CB-OD1 3.26Å; Y459-N461 WeakPolarHBondContact CB-OD1 3.33Å; Y459-N461 PolarHBondContact O-N 2.85Å; N461-V463 WeakPolarHBondContact OD1-CB 3.42Å; N461-V463 VanDerWaalsContact OD1-CG2 3.32Å; N461-V463 WeakPolarHBondContact OD1-CG2 3.11Å; N461-V463 PolarHBondContact OD1-N 3.2Å; N461-P696 VanDerWaalsContact C-CG 3.46Å; N461-P696 WeakPolarHBondContact O-CG 3.46Å
462G98.3Very high98.6Very high0 Ų011.9 Ų11.90%06%0.061CC..SBendtrans81.211.6179.200000114.6W311 Y459 P460 Y583 P688W311-G462 VanDerWaalsContact CH2-C 3.5Å; W311-G462 WeakPolarHBondContact CH2-O 3.4Å; W311-G462 VanDerWaalsContact CZ2-CA 3.4Å; Y459-G462 PolarHBondContact O-N 3.49Å; Y459-G462 VanDerWaalsContact O-N 3.15Å; P460-G462 VanDerWaalsContact C-N 3.35Å; G462-Y583 WeakPolarHBondContact O-CE1 3.47Å; G462-Y583 PolarHBondContact O-OH 3.07Å; G462-P688 WeakPolarHBondContact O-CD 3.4Å
463V98.9Very high98.6Very high9 Ų912.8 Ų12.86%0.0557%0.065CC..  trans-85.8137.2171.3173.80000110.5W311 Y459 N461 F685 L686 R687W311-V463 VanDerWaalsContact CZ2-O 3.31Å; W311-V463 WeakPolarHBondContact CZ2-O 3.05Å; Y459-V463 WeakPolarHBondContact CB-O 3.28Å; Y459-V463 HydrophobicContact CD2-CB 4.22Å; Y459-V463 HydrophobicContact CD2-CG1 4.01Å; Y459-V463 WeakPolarHBondContact CD2-O 3.11Å; Y459-V463 HydrophobicContact CG-CB 4.27Å; Y459-V463 HydrophobicContact CG-CG1 4.46Å; Y459-V463 PolarHBondContact N-O 3.43Å; N461-V463 WeakPolarHBondContact OD1-CB 3.42Å; N461-V463 VanDerWaalsContact OD1-CG2 3.32Å; N461-V463 WeakPolarHBondContact OD1-CG2 3.11Å; N461-V463 PolarHBondContact OD1-N 3.2Å; V463-F685 HydrophobicContact CG1-CB 4.43Å; V463-F685 HydrophobicContact CG1-CD1 3.89Å; V463-L686 WeakPolarHBondContact CA-O 3.24Å; V463-R687 HydrophobicContact CG1-CG 4.04Å; V463-R687 HydrophobicContact CG2-CB 4.22Å; V463-R687 HydrophobicContact CG2-CG 3.98Å
464V98.7Very high98.6Very high1 Ų111.5 Ų11.51%0.0066%0.059CC..EExtended strand (participates in β ladder)trans-111.1139.3164.3-179.30000109.1W311 L328 F456 L457 F458 F685 L686W311-V464 HydrophobicContact CE3-CG2 4.42Å; W311-V464 HydrophobicContact CH2-CG2 3.23Å; W311-V464 HydrophobicContact CZ2-CG2 3.83Å; W311-V464 HydrophobicContact CZ3-CG2 3.58Å; L328-V464 HydrophobicContact CD2-CG2 3.75Å; F456-V464 HydrophobicContact CD1-CG1 4.3Å; L457-V464 CarbonylContact O-C 3.58Å; L457-V464 WeakPolarHBondContact O-CA 3.35Å; F458-V464 HydrophobicContact CD1-CG1 4.28Å; F458-V464 HydrophobicContact CD1-CG2 3.81Å; F458-V464 HydrophobicContact CE1-CG1 4.18Å; F458-V464 HydrophobicContact CE1-CG2 4.19Å; V464-F685 CarbonylContact O-C 3.56Å; V464-F685 VanDerWaalsContact O-CA 3.25Å; V464-F685 WeakPolarHBondContact O-CA 3.25Å; V464-L686 HydrophobicContact CB-CB 4.4Å; V464-L686 PolarHBondContact N-O 3.43Å; V464-L686 PolarHBondContact O-N 3.34Å
465E98.8Very high98.5Very high18 Ų1811.5 Ų11.58%0.0846%0.059CC..EExtended strand (participates in β ladder)trans-114.5130.6169.1-179.5-178.4176.700109F456 L457 Y459 K467 F685F456-E465 CarbonylContact C-O 3.47Å; F456-E465 WeakPolarHBondContact CA-O 3.24Å; L457-E465 HydrophobicContact CB-CB 4.15Å; L457-E465 HydrophobicContact CD1-CB 4.12Å; L457-E465 HydrophobicContact CD1-CG 4.04Å; L457-E465 PolarHBondContact N-O 2.89Å; L457-E465 PolarHBondContact O-N 3.24Å; Y459-E465 HydrophobicContact CE2-CB 3.79Å; Y459-E465 WeakPolarHBondContact CE2-OE2 3.24Å; Y459-E465 PolarHBondContact OH-OE2 3.29Å; E465-K467 HydrophobicContact CG-CB 4.36Å; E465-F685 HydrophobicContact CB-CD1 3.61Å; E465-F685 HydrophobicContact CB-CE1 3.55Å; E465-F685 HydrophobicContact CB-CG 4.45Å; E465-F685 HydrophobicContact CB-CZ 4.31Å; E465-F685 HydrophobicContact CG-CD1 3.84Å; E465-F685 HydrophobicContact CG-CE1 3.42Å; E465-F685 VanDerWaalsContact CG-CE1 3.42Å; E465-F685 HydrophobicContact CG-CE2 4.3Å; E465-F685 HydrophobicContact CG-CG 4.44Å; E465-F685 HydrophobicContact CG-CZ 3.67Å; E465-F685 VanDerWaalsContact OE2-CE1 3.27Å; E465-F685 WeakPolarHBondContact OE2-CE1 3.02Å
466V98.9Very high98.5Very high1 Ų111.4 Ų11.41%0.0066%0.058CC..EExtended strand (participates in β ladder)trans-107.3124.2169.7-173.80000106.3I339 F456 Y505 G683 F684I339-V466 HydrophobicContact CG2-CG2 4.13Å; F456-V466 HydrophobicContact CD1-CG2 3.75Å; F456-V466 HydrophobicContact CE1-CB 4.36Å; F456-V466 HydrophobicContact CE1-CG1 4.09Å; F456-V466 HydrophobicContact CE1-CG2 3.5Å; F456-V466 HydrophobicContact CZ-CG1 4.29Å; F456-V466 HydrophobicContact CZ-CG2 4.45Å; V466-Y505 HydrophobicContact CG1-CD1 3.94Å; V466-Y505 HydrophobicContact CG1-CE1 3.51Å; V466-Y505 HydrophobicContact CG1-CE2 4.39Å; V466-G683 CarbonylContact O-C 3.37Å; V466-G683 WeakPolarHBondContact O-CA 3.2Å; V466-F684 HydrophobicContact CB-CD1 4.14Å; V466-F684 HydrophobicContact CB-CD2 4.46Å; V466-F684 HydrophobicContact CB-CE1 3.72Å; V466-F684 HydrophobicContact CB-CE2 4.07Å; V466-F684 HydrophobicContact CB-CG 4.49Å; V466-F684 HydrophobicContact CB-CZ 3.68Å; V466-F684 HydrophobicContact CG1-CE1 3.9Å; V466-F684 HydrophobicContact CG1-CZ 4.06Å; V466-F684 HydrophobicContact CG2-CD2 4.3Å; V466-F684 HydrophobicContact CG2-CE1 4.06Å; V466-F684 HydrophobicContact CG2-CE2 3.6Å; V466-F684 HydrophobicContact CG2-CZ 3.47Å; V466-F684 VanDerWaalsContact CG2-CZ 3.47Å; V466-F684 PolarHBondContact N-O 3.48Å; V466-F684 PolarHBondContact O-N 2.9Å
467K98.8Very high98.5Very high39 Ų3911.2 Ų11.217%0.176%0.057CC..EExtended strand (participates in β ladder)trans-140.3138-172.8-179.5-176.270.9-167.50110.4D455 L457 E465 A681 V682D455-K467 HydrophobicContact CB-CB 4.23Å; D455-K467 PolarHBondContact N-O 3.32Å; D455-K467 PolarHBondContact O-N 2.93Å; D455-K467 WeakPolarHBondContact OD2-CE 3.49Å; D455-K467 IonicContact OD2-NZ 2.78Å; D455-K467 PolarHBondContact OD2-NZ 3.32Å; D455-K467 VanDerWaalsContact OD2-NZ 3.16Å; L457-K467 HydrophobicContact CD1-CB 4.24Å; E465-K467 HydrophobicContact CG-CB 4.36Å; K467-A681 HydrophobicContact CD-CB 4.2Å; K467-A681 HydrophobicContact CG-CB 4.24Å; K467-V682 WeakPolarHBondContact CA-O 3.45Å
468V98.6Very high98.4Very high3 Ų311 Ų112%0.0186%0.056CC..EExtended strand (participates in β ladder)trans-118139167.256.20000109.1Y452 I453 W454 I503 A681 V682Y452-V468 HydrophobicContact CD1-CG2 4.17Å; I453-V468 VanDerWaalsContact O-CA 3.27Å; I453-V468 WeakPolarHBondContact O-CA 3.28Å; W454-V468 HydrophobicContact CD2-CG2 4.32Å; W454-V468 HydrophobicContact CE3-CB 3.67Å; W454-V468 HydrophobicContact CE3-CG2 3.54Å; W454-V468 HydrophobicContact CH2-CG2 3.81Å; W454-V468 HydrophobicContact CZ3-CB 3.55Å; W454-V468 HydrophobicContact CZ3-CG1 4.27Å; W454-V468 HydrophobicContact CZ3-CG2 3.23Å; V468-I503 HydrophobicContact CG1-CD1 3.98Å; V468-I503 HydrophobicContact CG1-CG1 4.1Å; V468-A681 CarbonylContact O-C 3.53Å; V468-A681 VanDerWaalsContact O-CA 3.27Å; V468-A681 WeakPolarHBondContact O-CA 3.37Å; V468-V682 HydrophobicContact CG1-CG2 3.58Å; V468-V682 WeakPolarHBondContact CG1-O 3.49Å; V468-V682 PolarHBondContact N-O 3.09Å; V468-V682 PolarHBondContact O-N 3.36Å
469S98.6Very high98.4Very high12 Ų1212.7 Ų12.78%0.0846%0.063CC..EExtended strand (participates in β ladder)trans-121.9134.1167.8-60.30000109.4I453 A681I453-S469 PolarHBondContact N-O 3Å; I453-S469 PolarHBondContact O-N 3.28Å; S469-A681 WeakPolarHBondContact OG-CB 3.41Å
470A97.7Very high98.3Very high2 Ų211.1 Ų11.12%0.0176%0.058CC..EExtended strand (participates in β ladder)trans-96.8135.2173.300000110.2Y450 Y452 F663 N680Y450-A470 HydrophobicContact CD1-CB 4.44Å; Y452-A470 HydrophobicContact CD1-CB 4.17Å; Y452-A470 HydrophobicContact CE1-CB 4.16Å; A470-F663 HydrophobicContact CB-CZ 4.06Å; A470-N680 PolarHBondContact N-O 3.32Å
471T98.6Very high98.2Very high30 Ų3014.9 Ų14.918%0.1848%0.082CC..EExtended strand (participates in β ladder)trans-145-163.8169.1-168.60000108.7Y450 D451 I453 T675 T677Y450-T471 WeakPolarHBondContact CD1-O 3.31Å; D451-T471 HydrophobicContact CB-CG2 3.67Å; D451-T471 PolarHBondContact N-O 2.92Å; D451-T471 PolarHBondContact O-N 3.27Å; I453-T471 HydrophobicContact CD1-CG2 4.35Å; T471-T675 VanDerWaalsContact CA-O 3.23Å; T471-T675 WeakPolarHBondContact CA-O 3.47Å; T471-T675 VanDerWaalsContact CB-O 3.29Å; T471-T675 WeakPolarHBondContact CB-O 3.45Å; T471-T675 PolarHBondContact OG1-O 3.27Å; T471-T677 HydrophobicContact CG2-CG2 4.31Å
472G98.2Very high98.1Very high0 Ų017.8 Ų17.80%010%0.098CC..EExtended strand (participates in β ladder)trans89.1-169.4-174.600000112.8D451 N674 T675D451-G472 VanDerWaalsContact OD2-CA 3.25Å; D451-G472 WeakPolarHBondContact OD2-CA 3.24Å; G472-N674 VanDerWaalsContact C-OD1 3.25Å; G472-N674 WeakPolarHBondContact CA-OD1 3.29Å; G472-N674 CarbonylContact O-C 3.54Å; G472-N674 VanDerWaalsContact O-CA 3.25Å; G472-N674 WeakPolarHBondContact O-CA 3.29Å; G472-N674 WeakPolarHBondContact O-CB 3.42Å; G472-N674 PolarHBondContact O-ND2 2.84Å; G472-T675 PolarHBondContact O-N 3.14Å
473Y98.8Very high98.1Very high23 Ų2317.8 Ų17.89%0.0910%0.098CC..PPolyproline II helixtrans-81.4141.7-179.6-70.5-88.6000111F210 I211 S272 Y274 N449 P673 N674F210-Y473 HydrophobicContact CB-CG 4.45Å; F210-Y473 HydrophobicContact CD2-CD1 4.23Å; F210-Y473 AromaticContact CD2-CD2 3.53Å; F210-Y473 HydrophobicContact CD2-CD2 3.53Å; F210-Y473 HydrophobicContact CD2-CE2 4.25Å; F210-Y473 AromaticContact CD2-CG 3.52Å; F210-Y473 HydrophobicContact CD2-CG 3.52Å; F210-Y473 AromaticContact CE2-CD2 3.72Å; F210-Y473 HydrophobicContact CE2-CD2 3.72Å; F210-Y473 HydrophobicContact CE2-CE2 4.3Å; F210-Y473 HydrophobicContact CE2-CG 4.2Å; F210-Y473 HydrophobicContact CG-CG 4.37Å; I211-Y473 HydrophobicContact CD1-CD1 4.03Å; I211-Y473 HydrophobicContact CD1-CE1 4.15Å; I211-Y473 HydrophobicContact CG1-CD1 4.25Å; S272-Y473 WeakPolarHBondContact O-CE1 3.28Å; S272-Y473 PolarHBondContact O-OH 3.35Å; Y274-Y473 HydrophobicContact CE2-CE2 4.38Å; N449-Y473 CarbonylContact C-O 3.49Å; N449-Y473 PolarHBondContact ND2-O 2.88Å; N449-Y473 PolarHBondContact O-N 3.42Å; Y473-P673 VanDerWaalsContact CD1-O 3.25Å; Y473-P673 WeakPolarHBondContact CD1-O 3.46Å; Y473-P673 HydrophobicContact CE1-CB 4.22Å; Y473-P673 WeakPolarHBondContact CE1-O 3.28Å; Y473-N674 WeakPolarHBondContact CD1-ND2 3.31Å; Y473-N674 WeakPolarHBondContact CD2-ND2 3.02Å; Y473-N674 WeakPolarHBondContact CE1-ND2 3.38Å; Y473-N674 VanDerWaalsContact CE2-ND2 3.33Å; Y473-N674 WeakPolarHBondContact CE2-ND2 3.43Å; Y473-N674 VanDerWaalsContact CZ-ND2 3.31Å; Y473-N674 PolarHBondContact N-ND2 3.32Å
474I98.5Very high98.1Very high0 Ų022 Ų220%012%0.119CC..PPolyproline II helixtrans-67.7151.816962.7175.1000111I211 A476 V490 P667 D671 T675I211-I474 HydrophobicContact CG2-CD1 4.47Å; I211-I474 HydrophobicContact CG2-CG1 3.78Å; I474-A476 HydrophobicContact CD1-CB 4.41Å; I474-A476 HydrophobicContact CG1-CB 4.31Å; I474-A476 PolarHBondContact O-N 3.44Å; I474-V490 HydrophobicContact CD1-CG2 4.24Å; I474-P667 HydrophobicContact CD1-CB 3.94Å; I474-P667 HydrophobicContact CD1-CG 4.48Å; I474-P667 HydrophobicContact CG2-CB 4.38Å; I474-P667 HydrophobicContact CG2-CG 4.46Å; I474-D671 HydrophobicContact CG2-CB 4Å; I474-T675 WeakPolarHBondContact CG2-OG1 3.29Å
475H98Very high98Very high3 Ų329.2 Ų29.21%0.01415%0.152CC..PPolyproline II helixtrans-79116.8164.2176.162.3000107.9Y348 T358 N449Y348-H475 HydrophobicContact CD1-CB 4.46Å; Y348-H475 AromaticContact CD1-CD2 3.83Å; Y348-H475 HydrophobicContact CE1-CB 3.64Å; Y348-H475 AromaticContact CE1-CD2 3.87Å; Y348-H475 HydrophobicContact CE2-CB 4.4Å; T358-H475 PolarHBondContact OG1-NE2 3.26Å; N449-H475 PolarHBondContact ND2-N 3.14Å; N449-H475 VanDerWaalsContact ND2-N 3.19Å
476A98.2Very high98Very high0 Ų033 Ų330%017%0.166CC..EExtended strand (participates in β ladder)trans-125.3143.3-17400000111.6M201 I211 I474 V494 L495M201-A476 WeakPolarHBondContact CE-O 3.23Å; I211-A476 HydrophobicContact CB-CB 4.49Å; I211-A476 HydrophobicContact CG2-CB 3.93Å; I474-A476 HydrophobicContact CD1-CB 4.41Å; I474-A476 HydrophobicContact CG1-CB 4.31Å; I474-A476 PolarHBondContact O-N 3.44Å; A476-V494 HydrophobicContact CB-CG1 3.66Å; A476-L495 VanDerWaalsContact CA-O 3.29Å; A476-L495 WeakPolarHBondContact CA-O 3.45Å; A476-L495 VanDerWaalsContact CB-O 3.31Å; A476-L495 WeakPolarHBondContact CB-O 3.4Å
477T98.5Very high98Very high0 Ų033.6 Ų33.60%017%0.173CC..EExtended strand (participates in β ladder)trans-114.3169.2174.761.80000112M201 P213 A355 F479 L495 N497M201-T477 HydrophobicContact CE-CG2 4.42Å; M201-T477 HydrophobicContact SD-CG2 4.26Å; P213-T477 VanDerWaalsContact CG-C 3.42Å; P213-T477 WeakPolarHBondContact CG-O 3.43Å; A355-T477 HydrophobicContact CB-CG2 3.6Å; T477-F479 PolarHBondContact O-N 3.11Å; T477-L495 PolarHBondContact N-O 3.02Å; T477-L495 VanDerWaalsContact N-O 3.15Å; T477-L495 PolarHBondContact O-N 3.32Å; T477-N497 PolarHBondContact N-OD1 2.71Å; T477-N497 PolarHBondContact OG1-ND2 3.33Å; T477-N497 VanDerWaalsContact OG1-ND2 3.07Å; T477-N497 PolarHBondContact OG1-OD1 2.59Å; T477-N497 VanDerWaalsContact OG1-OD1 3.08Å
478F98.1Very high98Very high3 Ų334 Ų341%0.01318%0.179CC..EExtended strand (participates in β ladder)trans-59.7133.9178-172.3-107.2000110.7P213 G215 W236 L260 L262 T480 Y493P213-F478 HydrophobicContact CB-CB 4.22Å; P213-F478 HydrophobicContact CG-CB 4.43Å; G215-F478 VanDerWaalsContact CA-CB 3.46Å; W236-F478 HydrophobicContact CH2-CB 4.48Å; W236-F478 HydrophobicContact CH2-CD1 4.28Å; W236-F478 HydrophobicContact CZ3-CB 4.46Å; L260-F478 HydrophobicContact CD1-CE1 3.82Å; L260-F478 HydrophobicContact CD1-CE2 4.44Å; L260-F478 HydrophobicContact CD1-CZ 3.52Å; L260-F478 HydrophobicContact CD2-CZ 4.49Å; L262-F478 HydrophobicContact CD2-CE2 3.67Å; L262-F478 HydrophobicContact CD2-CZ 4.25Å; F478-T480 HydrophobicContact CD1-CG2 4.43Å; F478-T480 PolarHBondContact O-N 3.47Å; F478-Y493 AromaticContact CE2-CD1 3.66Å; F478-Y493 HydrophobicContact CE2-CD1 3.66Å; F478-Y493 HydrophobicContact CE2-CG 4.13Å; F478-Y493 AromaticContact CZ-CD1 3.66Å; F478-Y493 HydrophobicContact CZ-CD1 3.66Å; F478-Y493 HydrophobicContact CZ-CE1 4.38Å
479F97.8Very high98Very high36 Ų3638 Ų3816%0.15820%0.196CC..  trans-70.8126.5179.5170.3-102.6000111.4T477 L484 K489 Y493 L495T477-F479 PolarHBondContact O-N 3.11Å; F479-L484 HydrophobicContact CE2-CD1 4.46Å; F479-L484 HydrophobicContact CE2-CD2 3.93Å; F479-L484 HydrophobicContact CE2-CG 3.98Å; F479-K489 HydrophobicContact CD1-CD 4.15Å; F479-K489 HydrophobicContact CD2-CB 3.88Å; F479-K489 HydrophobicContact CD2-CD 4Å; F479-K489 HydrophobicContact CD2-CG 3.81Å; F479-K489 HydrophobicContact CE1-CD 3.97Å; F479-K489 HydrophobicContact CE2-CB 3.83Å; F479-K489 HydrophobicContact CE2-CD 3.81Å; F479-K489 HydrophobicContact CE2-CG 3.98Å; F479-K489 HydrophobicContact CG-CD 4.17Å; F479-K489 HydrophobicContact CG-CG 4.16Å; F479-K489 HydrophobicContact CZ-CD 3.8Å; F479-K489 HydrophobicContact CZ-CG 4.47Å; F479-Y493 VanDerWaalsContact CB-C 3.42Å; F479-Y493 PolarHBondContact N-O 3.11Å; F479-L495 HydrophobicContact CB-CB 4.48Å; F479-L495 HydrophobicContact CD2-CD1 4.16Å
480T96Very high97.9Very high2 Ų238.1 Ų38.11%0.01220%0.196CC..  trans-123.7155.6165.772.30000108.4W236 S239 D351 F478 N482 G483W236-T480 HydrophobicContact CH2-CG2 4.07Å; W236-T480 HydrophobicContact CZ2-CG2 4.08Å; S239-T480 VanDerWaalsContact OG-CG2 3.23Å; S239-T480 WeakPolarHBondContact OG-CG2 3.33Å; D351-T480 PolarHBondContact OD2-OG1 3.3Å; F478-T480 HydrophobicContact CD1-CG2 4.43Å; F478-T480 PolarHBondContact O-N 3.47Å; T480-N482 PolarHBondContact O-N 3.27Å; T480-G483 WeakPolarHBondContact O-CA 3.45Å; T480-G483 PolarHBondContact O-N 2.87Å; T480-G483 PolarHBondContact OG1-N 3.03Å
481P96.1Very high97.9Very high97 Ų9742.7 Ų42.763%0.6321%0.214SC*.G310 helixtrans-55.6-38.1174.2-27.636000113.5G483 L484P481-G483 VanDerWaalsContact C-N 3.27Å; P481-G483 PolarHBondContact O-N 2.71Å; P481-L484 PolarHBondContact O-N 2.78Å
482N97Very high97.6Very high95 Ų9545.4 Ų45.451%0.50823%0.227SC..G310 helixtrans-68.7-26.3176.7-73.6-11.1000112.7D351 T480 L484 H485D351-N482 HydrophobicContact CB-CB 4.41Å; D351-N482 VanDerWaalsContact OD1-CB 3.25Å; D351-N482 WeakPolarHBondContact OD1-CB 3.21Å; T480-N482 PolarHBondContact O-N 3.27Å; N482-L484 PolarHBondContact O-N 3.21Å; N482-L484 VanDerWaalsContact O-N 3.09Å; N482-H485 PolarHBondContact O-CD2 2.99Å; N482-H485 PolarHBondContact O-N 3.39Å; N482-H485 VanDerWaalsContact O-N 3.09Å
483G97.5Very high97.4Very high0 Ų049.3 Ų49.30%024%0.242CC..G310 helixtrans-54.5-25.5175.200000114.3T480 P481 H485 Y486 G487 L495T480-G483 WeakPolarHBondContact O-CA 3.45Å; T480-G483 PolarHBondContact O-N 2.87Å; T480-G483 PolarHBondContact OG1-N 3.03Å; P481-G483 VanDerWaalsContact C-N 3.27Å; P481-G483 PolarHBondContact O-N 2.71Å; G483-H485 PolarHBondContact O-N 3.44Å; G483-H485 VanDerWaalsContact O-N 3.14Å; G483-Y486 CarbonylContact O-C 3.48Å; G483-Y486 WeakPolarHBondContact O-CA 3.43Å; G483-Y486 PolarHBondContact O-N 2.83Å; G483-G487 PolarHBondContact O-N 3.46Å; G483-L495 WeakPolarHBondContact O-CD2 3.26Å
484L98.1Very high97.3Very high97 Ų9748.3 Ų48.351%0.50824%0.239SC..G310 helixtrans-64.1-15.9177.3-66176.8000114.1F479 P481 N482 Y486 K489F479-L484 HydrophobicContact CE2-CD1 4.46Å; F479-L484 HydrophobicContact CE2-CD2 3.93Å; F479-L484 HydrophobicContact CE2-CG 3.98Å; P481-L484 PolarHBondContact O-N 2.78Å; N482-L484 PolarHBondContact O-N 3.21Å; N482-L484 VanDerWaalsContact O-N 3.09Å; L484-Y486 PolarHBondContact O-N 3.48Å; L484-K489 HydrophobicContact CD2-CB 4.12Å
485H98Very high97.4Very high152 Ų15248.4 Ų48.470%0.70424%0.239SC*.G310 helixtrans-74.4-15.8170.2-68.4-59.1000113.3N482 G483N482-H485 PolarHBondContact O-CD2 2.99Å; N482-H485 PolarHBondContact O-N 3.39Å; N482-H485 VanDerWaalsContact O-N 3.09Å; G483-H485 PolarHBondContact O-N 3.44Å; G483-H485 VanDerWaalsContact O-N 3.14Å
486Y98.3Very high97.4Very high97 Ų9748.2 Ų48.238%0.3824%0.239SC..SBendtrans-128.615.9-169.9-53.4-70.8000112.9A349 D351 G483 L484 L498A349-Y486 HydrophobicContact CB-CD1 3.96Å; D351-Y486 HydrophobicContact CB-CD2 4.07Å; D351-Y486 HydrophobicContact CB-CE2 4.33Å; G483-Y486 CarbonylContact O-C 3.48Å; G483-Y486 WeakPolarHBondContact O-CA 3.43Å; G483-Y486 PolarHBondContact O-N 2.83Å; L484-Y486 PolarHBondContact O-N 3.48Å; Y486-L498 WeakPolarHBondContact O-CB 3.36Å; Y486-L498 PolarHBondContact O-N 3.22Å
487G98.2Very high97.4Very high14 Ų1448.2 Ų48.214%0.14424%0.239CC..EExtended strand (participates in β ladder)trans165.6-167.1-177.900000113.1G483 G496G483-G487 PolarHBondContact O-N 3.46Å; G487-G496 WeakPolarHBondContact CA-O 3.42Å
488T98.7Very high97.4Very high48 Ų4850.5 Ų50.529%0.29425%0.251SS..EExtended strand (participates in β ladder)trans-119137.7-179.9-51.20000109.7V490 G496 P667T488-V490 PolarHBondContact O-N 3.1Å; T488-V490 VanDerWaalsContact O-N 3.15Å; T488-G496 PolarHBondContact N-O 3.32Å; T488-G496 VanDerWaalsContact N-O 3.07Å; T488-G496 PolarHBondContact O-N 2.71Å; T488-P667 WeakPolarHBondContact CB-O 3.49Å; T488-P667 PolarHBondContact OG1-O 3.12Å
489K98.4Very high97.4Very high88 Ų8850.4 Ų50.438%0.38325%0.25SS..EExtended strand (participates in β ladder)trans-69.6107.5166.9-175.3-178.7-176.9170.10108.6F479 L484 Y491 D492F479-K489 HydrophobicContact CD1-CD 4.15Å; F479-K489 HydrophobicContact CD2-CB 3.88Å; F479-K489 HydrophobicContact CD2-CD 4Å; F479-K489 HydrophobicContact CD2-CG 3.81Å; F479-K489 HydrophobicContact CE1-CD 3.97Å; F479-K489 HydrophobicContact CE2-CB 3.83Å; F479-K489 HydrophobicContact CE2-CD 3.81Å; F479-K489 HydrophobicContact CE2-CG 3.98Å; F479-K489 HydrophobicContact CG-CD 4.17Å; F479-K489 HydrophobicContact CG-CG 4.16Å; F479-K489 HydrophobicContact CZ-CD 3.8Å; F479-K489 HydrophobicContact CZ-CG 4.47Å; L484-K489 HydrophobicContact CD2-CB 4.12Å; K489-Y491 WeakPolarHBondContact CE-O 3.28Å; K489-Y491 WeakPolarHBondContact CG-O 3.42Å; K489-D492 VanDerWaalsContact CE-C 3.44Å; K489-D492 WeakPolarHBondContact CE-O 3.38Å; K489-D492 PolarHBondContact NZ-O 3.45Å
490V98Very high97.4Very high14 Ų1449.7 Ų49.79%0.08525%0.248CC..EExtended strand (participates in β ladder)trans-98.9-16.4-176.5-64.40000112.8I474 T488 V494 I672I474-V490 HydrophobicContact CD1-CG2 4.24Å; T488-V490 PolarHBondContact O-N 3.1Å; T488-V490 VanDerWaalsContact O-N 3.15Å; V490-V494 HydrophobicContact CG2-CB 4.04Å; V490-V494 HydrophobicContact CG2-CG1 3.7Å; V490-V494 PolarHBondContact N-O 3.44Å; V490-I672 HydrophobicContact CB-CD1 4.17Å; V490-I672 HydrophobicContact CB-CG1 4.06Å; V490-I672 HydrophobicContact CG2-CD1 3.93Å; V490-I672 HydrophobicContact CG2-CG1 4.36Å
491Y96.1Very high97.6Very high98 Ų9849.6 Ų49.638%0.38425%0.248SC..EExtended strand (participates in β ladder)trans-155.2175.9171.3-155.3-106.5000109.8Y271 K489 Y493 V494Y271-Y491 AromaticContact CD1-CD1 3.78Å; Y271-Y491 HydrophobicContact CD1-CD1 3.78Å; Y271-Y491 HydrophobicContact CD1-CD2 4.15Å; Y271-Y491 AromaticContact CD1-CE1 3.37Å; Y271-Y491 HydrophobicContact CD1-CE1 3.37Å; Y271-Y491 AromaticContact CD1-CE2 3.78Å; Y271-Y491 HydrophobicContact CD1-CE2 3.78Å; Y271-Y491 HydrophobicContact CD1-CG 4.15Å; Y271-Y491 AromaticContact CD1-CZ 3.36Å; Y271-Y491 HydrophobicContact CD2-CD1 4.36Å; Y271-Y491 AromaticContact CD2-CD2 3.96Å; Y271-Y491 HydrophobicContact CD2-CD2 3.96Å; Y271-Y491 HydrophobicContact CD2-CE2 4.27Å; Y271-Y491 HydrophobicContact CD2-CG 4Å; Y271-Y491 AromaticContact CE1-CD1 3.55Å; Y271-Y491 HydrophobicContact CE1-CD1 3.55Å; Y271-Y491 AromaticContact CE1-CE1 3.44Å; Y271-Y491 HydrophobicContact CE1-CE1 3.44Å; Y271-Y491 VanDerWaalsContact CE1-CE1 3.44Å; Y271-Y491 HydrophobicContact CE1-CG 4.17Å; Y271-Y491 AromaticContact CE1-CZ 3.97Å; Y271-Y491 HydrophobicContact CE2-CD1 4.14Å; Y271-Y491 HydrophobicContact CE2-CD2 4.41Å; Y271-Y491 AromaticContact CE2-CG 3.98Å; Y271-Y491 HydrophobicContact CE2-CG 3.98Å; Y271-Y491 HydrophobicContact CG-CD1 4.19Å; Y271-Y491 AromaticContact CG-CD2 3.81Å; Y271-Y491 HydrophobicContact CG-CD2 3.81Å; Y271-Y491 HydrophobicContact CG-CE1 4.05Å; Y271-Y491 AromaticContact CG-CE2 3.64Å; Y271-Y491 HydrophobicContact CG-CE2 3.64Å; Y271-Y491 HydrophobicContact CG-CG 4.08Å; Y271-Y491 AromaticContact CG-CZ 3.75Å; Y271-Y491 AromaticContact CZ-CD1 3.75Å; K489-Y491 WeakPolarHBondContact CE-O 3.28Å; K489-Y491 WeakPolarHBondContact CG-O 3.42Å; Y491-Y493 VanDerWaalsContact C-N 3.25Å; Y491-Y493 PolarHBondContact O-N 3.32Å; Y491-V494 HydrophobicContact CD1-CG2 4.49Å; Y491-V494 PolarHBondContact N-O 3.3Å; Y491-V494 PolarHBondContact O-N 3.29Å
492D92.6Very high97.7Very high87 Ų8745 Ų4547%0.46522%0.218SC..THydrogen-bonded Turntrans-51.5-39.3-169.1-75.4-15.1000115K489K489-D492 VanDerWaalsContact CE-C 3.44Å; K489-D492 WeakPolarHBondContact CE-O 3.38Å; K489-D492 PolarHBondContact NZ-O 3.45Å
493Y94.6Very high97.8Very high81 Ų8140.6 Ų40.632%0.31820%0.195SC..THydrogen-bonded Turntrans-126.119-179.2-67-85.4000113L262 P263 F478 F479 Y491L262-Y493 HydrophobicContact CD2-CD1 3.8Å; L262-Y493 HydrophobicContact CD2-CD2 4.25Å; L262-Y493 HydrophobicContact CD2-CE1 4.18Å; L262-Y493 HydrophobicContact CD2-CG 3.81Å; P263-Y493 VanDerWaalsContact CD-CD2 3.49Å; P263-Y493 HydrophobicContact CG-CD2 3.92Å; P263-Y493 HydrophobicContact CG-CE2 3.6Å; F478-Y493 AromaticContact CE2-CD1 3.66Å; F478-Y493 HydrophobicContact CE2-CD1 3.66Å; F478-Y493 HydrophobicContact CE2-CG 4.13Å; F478-Y493 AromaticContact CZ-CD1 3.66Å; F478-Y493 HydrophobicContact CZ-CD1 3.66Å; F478-Y493 HydrophobicContact CZ-CE1 4.38Å; F479-Y493 VanDerWaalsContact CB-C 3.42Å; F479-Y493 PolarHBondContact N-O 3.11Å; Y491-Y493 VanDerWaalsContact C-N 3.25Å; Y491-Y493 PolarHBondContact O-N 3.32Å
494V97.6Very high97.8Very high3 Ų340.7 Ų40.72%0.01820%0.195CC..EExtended strand (participates in β ladder)trans-121.7120.1-171.3-170.40000109.8I211 Y271 A476 V490 Y491I211-V494 HydrophobicContact CB-CG1 4.2Å; I211-V494 WeakPolarHBondContact O-CG2 3.48Å; Y271-V494 HydrophobicContact CE2-CG2 4.42Å; Y271-V494 WeakPolarHBondContact OH-CG2 3.47Å; A476-V494 HydrophobicContact CB-CG1 3.66Å; V490-V494 HydrophobicContact CG2-CB 4.04Å; V490-V494 HydrophobicContact CG2-CG1 3.7Å; V490-V494 PolarHBondContact N-O 3.44Å; Y491-V494 HydrophobicContact CD1-CG2 4.49Å; Y491-V494 PolarHBondContact N-O 3.3Å; Y491-V494 PolarHBondContact O-N 3.29Å
495L98.7Very high97.9Very high1 Ų136.3 Ų36.31%0.00517%0.172CC..EExtended strand (participates in β ladder)trans-100.4121.2169.9-172.580.3000108.7A476 T477 F479 G483 N497A476-L495 VanDerWaalsContact CA-O 3.29Å; A476-L495 WeakPolarHBondContact CA-O 3.45Å; A476-L495 VanDerWaalsContact CB-O 3.31Å; A476-L495 WeakPolarHBondContact CB-O 3.4Å; T477-L495 PolarHBondContact N-O 3.02Å; T477-L495 VanDerWaalsContact N-O 3.15Å; T477-L495 PolarHBondContact O-N 3.32Å; F479-L495 HydrophobicContact CB-CB 4.48Å; F479-L495 HydrophobicContact CD2-CD1 4.16Å; G483-L495 WeakPolarHBondContact O-CD2 3.26Å; L495-N497 PolarHBondContact O-N 3.07Å; L495-N497 PolarHBondContact O-OD1 2.75Å; L495-N497 VanDerWaalsContact O-OD1 3.11Å
496G98.6Very high97.9Very high0 Ų029.5 Ų29.50%014%0.14CC..EExtended strand (participates in β ladder)trans-79.5109.2164.900000109.3G487 T488G487-G496 WeakPolarHBondContact CA-O 3.42Å; T488-G496 PolarHBondContact N-O 3.32Å; T488-G496 VanDerWaalsContact N-O 3.07Å; T488-G496 PolarHBondContact O-N 2.71Å
497N98.8Very high97.9Very high0 Ų024.9 Ų24.90%012%0.122CC..EExtended strand (participates in β ladder)trans-72.9135.5-173.5-65.581.6000112Y348 A349 A355 T477 L495 H499 P667Y348-N497 HydrophobicContact CD1-CB 3.81Å; A349-N497 PolarHBondContact O-ND2 2.88Å; A355-N497 WeakPolarHBondContact CB-ND2 3.18Å; T477-N497 PolarHBondContact N-OD1 2.71Å; T477-N497 PolarHBondContact OG1-ND2 3.33Å; T477-N497 VanDerWaalsContact OG1-ND2 3.07Å; T477-N497 PolarHBondContact OG1-OD1 2.59Å; T477-N497 VanDerWaalsContact OG1-OD1 3.08Å; L495-N497 PolarHBondContact O-N 3.07Å; L495-N497 PolarHBondContact O-OD1 2.75Å; L495-N497 VanDerWaalsContact O-OD1 3.11Å; N497-H499 PolarHBondContact O-N 2.87Å; N497-H499 PolarHBondContact O-ND1 2.92Å; N497-P667 VanDerWaalsContact O-CD 3.24Å; N497-P667 WeakPolarHBondContact O-CD 3.21Å; N497-P667 VanDerWaalsContact O-CG 3.28Å; N497-P667 WeakPolarHBondContact O-CG 3.4Å
498L98.1Very high98Very high48 Ų4824.2 Ų24.225%0.25112%0.115SC..  trans-57132.4170.6176.166.1000110.2Y348 A349 Y486 L664 V666Y348-L498 CarbonylContact C-O 3.45Å; Y348-L498 WeakPolarHBondContact CA-O 3.24Å; A349-L498 PolarHBondContact N-O 2.74Å; Y486-L498 WeakPolarHBondContact O-CB 3.36Å; Y486-L498 PolarHBondContact O-N 3.22Å; L498-L664 HydrophobicContact CD1-CD1 3.71Å; L498-L664 HydrophobicContact CD1-CG 4.19Å; L498-L664 HydrophobicContact CG-CD1 4.44Å; L498-V666 HydrophobicContact CD1-CB 4.27Å; L498-V666 HydrophobicContact CD1-CG2 3.51Å
499H98.4Very high98Very high1 Ų121.9 Ų21.91%0.00510%0.101CC..EExtended strand (participates in β ladder)trans-155164.9174.157.5-75.3000113.3F347 Y348 Y450 N497 H501 H665F347-H499 CarbonylContact O-C 3.57Å; F347-H499 WeakPolarHBondContact O-CA 3.36Å; F347-H499 VanDerWaalsContact O-CB 3.24Å; F347-H499 WeakPolarHBondContact O-CB 3.17Å; Y348-H499 HydrophobicContact CD1-CB 3.44Å; Y348-H499 VanDerWaalsContact CD1-CB 3.44Å; Y348-H499 AromaticContact CD1-CG 3.75Å; Y348-H499 AromaticContact CD1-ND1 3.84Å; Y348-H499 HydrophobicContact CD2-CB 4.17Å; Y348-H499 HydrophobicContact CE1-CB 3.54Å; Y348-H499 AromaticContact CE1-CD2 3.93Å; Y348-H499 AromaticContact CE1-CE1 3.94Å; Y348-H499 AromaticContact CE1-CG 3.31Å; Y348-H499 AromaticContact CE1-ND1 3.32Å; Y348-H499 VanDerWaalsContact CE1-ND1 3.32Å; Y348-H499 WeakPolarHBondContact CE1-ND1 3.43Å; Y348-H499 HydrophobicContact CE2-CB 4.28Å; Y348-H499 HydrophobicContact CG-CB 3.74Å; Y348-H499 AromaticContact CZ-CD2 3.91Å; Y348-H499 AromaticContact CZ-CG 3.71Å; Y450-H499 AromaticContact CZ-NE2 3.67Å; Y450-H499 PolarHBondContact OH-CE1 2.84Å; Y450-H499 PolarHBondContact OH-NE2 2.8Å; N497-H499 PolarHBondContact O-N 2.87Å; N497-H499 PolarHBondContact O-ND1 2.92Å; H499-H501 AromaticContact CD2-CD2 3.81Å; H499-H501 AromaticContact CD2-NE2 3.46Å; H499-H501 PolarHBondContact CD2-NE2 2.86Å; H499-H501 AromaticContact NE2-CD2 3.83Å; H499-H501 AromaticContact NE2-CE1 3.91Å; H499-H501 AromaticContact NE2-NE2 3.15Å; H499-H501 PolarHBondContact NE2-NE2 2.86Å; H499-H501 VanDerWaalsContact NE2-NE2 3.15Å; H499-H665 AromaticContact CE1-CG 3.68Å; H499-H665 AromaticContact CE1-ND1 3.25Å; H499-H665 PolarHBondContact CE1-ND1 3.35Å; H499-H665 VanDerWaalsContact CE1-ND1 3.25Å; H499-H665 PolarHBondContact N-O 3.47Å; H499-H665 AromaticContact NE2-CG 3.76Å; H499-H665 AromaticContact NE2-ND1 3.22Å; H499-H665 PolarHBondContact NE2-ND1 2.93Å; H499-H665 PolarHBondContact O-N 3.11Å; H499-H665 VanDerWaalsContact O-O 3.09Å
500T98.4Very high98Very high20 Ų2017.7 Ų17.712%0.1238%0.083CC..EExtended strand (participates in β ladder)trans-117.5129174.2-560000109.8A346 F347 L502 L664A346-T500 WeakPolarHBondContact CA-O 3.36Å; F347-T500 PolarHBondContact N-O 3.04Å; F347-T500 VanDerWaalsContact N-O 3.12Å; F347-T500 PolarHBondContact O-N 2.92Å; T500-L502 HydrophobicContact CG2-CD2 4.09Å; T500-L502 HydrophobicContact CG2-CG 4.04Å; T500-L664 WeakPolarHBondContact OG1-CD1 3.31Å
501H98.6Very high98Very high1 Ų117 Ų171%0.0058%0.079CC..EExtended strand (participates in β ladder)trans-87126165.8-67.1-84.2000109.3I345 Y450 Y452 H499 I503 G662 F663I345-H501 WeakPolarHBondContact O-CA 3.37Å; Y450-H501 AromaticContact CD1-CE1 3.91Å; Y450-H501 AromaticContact CE1-CE1 3.63Å; Y450-H501 AromaticContact CE1-NE2 3.68Å; Y450-H501 AromaticContact CZ-CE1 3.83Å; Y450-H501 AromaticContact CZ-NE2 3.85Å; Y452-H501 AromaticContact CE1-ND1 3.75Å; Y452-H501 AromaticContact CZ-ND1 3.93Å; Y452-H501 PolarHBondContact OH-ND1 3.03Å; H499-H501 AromaticContact CD2-CD2 3.81Å; H499-H501 AromaticContact CD2-NE2 3.46Å; H499-H501 PolarHBondContact CD2-NE2 2.86Å; H499-H501 AromaticContact NE2-CD2 3.83Å; H499-H501 AromaticContact NE2-CE1 3.91Å; H499-H501 AromaticContact NE2-NE2 3.15Å; H499-H501 PolarHBondContact NE2-NE2 2.86Å; H499-H501 VanDerWaalsContact NE2-NE2 3.15Å; H501-I503 HydrophobicContact CB-CD1 4.3Å; H501-G662 CarbonylContact O-C 3.35Å; H501-G662 WeakPolarHBondContact O-CA 3.46Å; H501-F663 HydrophobicContact CB-CD1 4.41Å; H501-F663 HydrophobicContact CB-CE1 4.13Å; H501-F663 HydrophobicContact CB-CZ 4.28Å; H501-F663 AromaticContact CD2-CE2 3.58Å; H501-F663 AromaticContact CD2-CZ 3.52Å; H501-F663 PolarHBondContact N-O 2.92Å; H501-F663 PolarHBondContact O-N 2.89Å
502L98.6Very high97.9Very high0 Ų014.3 Ų14.30%07%0.072CC..EExtended strand (participates in β ladder)trans-127.4137.8164.4-58176.7000110.1A344 I345 T500 A591 V594 W607 T660 V661A344-L502 CarbonylContact C-O 3.49Å; A344-L502 WeakPolarHBondContact CA-O 3.42Å; I345-L502 HydrophobicContact CD1-CB 3.85Å; I345-L502 HydrophobicContact CD1-CD1 4Å; I345-L502 HydrophobicContact CD1-CG 4.19Å; I345-L502 HydrophobicContact CG1-CB 3.72Å; I345-L502 HydrophobicContact CG1-CG 4.4Å; I345-L502 PolarHBondContact N-O 3.41Å; I345-L502 PolarHBondContact O-N 2.83Å; I345-L502 VanDerWaalsContact O-N 3.14Å; T500-L502 HydrophobicContact CG2-CD2 4.09Å; T500-L502 HydrophobicContact CG2-CG 4.04Å; L502-A591 HydrophobicContact CD2-CB 3.51Å; L502-V594 HydrophobicContact CD1-CB 4.24Å; L502-V594 HydrophobicContact CD1-CG1 3.97Å; L502-W607 HydrophobicContact CB-CH2 4.14Å; L502-W607 HydrophobicContact CB-CZ3 3.92Å; L502-T660 HydrophobicContact CB-CG2 4.17Å; L502-T660 HydrophobicContact CD2-CG2 4.24Å; L502-V661 CarbonylContact C-O 3.58Å; L502-V661 WeakPolarHBondContact CA-O 3.36Å
503I98.8Very high98Very high3 Ų311.4 Ų11.42%0.0156%0.063CC..EExtended strand (participates in β ladder)trans-127.7132.9-177.7-59.287.5000107.9L341 E343 A344 W454 V468 H501 Y505 T660 V661 V682L341-I503 HydrophobicContact CD1-CG2 3.52Å; E343-I503 WeakPolarHBondContact O-CA 3.24Å; A344-I503 HydrophobicContact CB-CG1 4.32Å; W454-I503 HydrophobicContact CH2-CG1 4.26Å; W454-I503 HydrophobicContact CH2-CG2 4.19Å; W454-I503 HydrophobicContact CZ3-CG1 4.26Å; W454-I503 HydrophobicContact CZ3-CG2 3.77Å; V468-I503 HydrophobicContact CG1-CD1 3.98Å; V468-I503 HydrophobicContact CG1-CG1 4.1Å; H501-I503 HydrophobicContact CB-CD1 4.3Å; I503-Y505 HydrophobicContact CB-CE2 4.17Å; I503-Y505 HydrophobicContact CG2-CD2 3.99Å; I503-Y505 HydrophobicContact CG2-CE2 3.29Å; I503-T660 WeakPolarHBondContact O-CA 3.33Å; I503-V661 HydrophobicContact CB-CG2 4.1Å; I503-V661 PolarHBondContact N-O 3.49Å; I503-V661 PolarHBondContact O-N 2.77Å; I503-V682 HydrophobicContact CD1-CG2 4.4Å
504H98.9Very high98.1Very high1 Ų112.2 Ų12.21%0.0057%0.065CC..EExtended strand (participates in β ladder)trans-113.1134.8-178.4-159.9-127.7000112Q342 E343 W607 S624 W658 V659 T660Q342-H504 HydrophobicContact CB-CB 4.27Å; Q342-H504 WeakPolarHBondContact CB-O 3.42Å; Q342-H504 PolarHBondContact N-O 2.89Å; E343-H504 HydrophobicContact CB-CB 4.38Å; E343-H504 PolarHBondContact N-O 3.01Å; E343-H504 PolarHBondContact O-N 3.36Å; H504-W607 HydrophobicContact CB-CD2 3.85Å; H504-W607 HydrophobicContact CB-CE3 3.55Å; H504-W607 HydrophobicContact CB-CG 4.47Å; H504-W607 HydrophobicContact CB-CH2 4.32Å; H504-W607 HydrophobicContact CB-CZ3 3.81Å; H504-W607 AromaticContact CD2-CE3 3.82Å; H504-W607 AromaticContact CG-CD2 3.84Å; H504-W607 AromaticContact CG-CE3 3.69Å; H504-W607 AromaticContact ND1-CG 3.89Å; H504-S624 PolarHBondContact CE1-OG 2.96Å; H504-S624 WeakPolarHBondContact ND1-CB 3.12Å; H504-S624 PolarHBondContact ND1-OG 2.88Å; H504-W658 AromaticContact CE1-CE3 3.62Å; H504-V659 WeakPolarHBondContact CA-O 3.25Å; H504-V659 PolarHBondContact CD2-O 3.05Å; H504-T660 PolarHBondContact CD2-OG1 3.1Å
505Y98.9Very high98.1Very high5 Ų516.1 Ų16.12%0.029%0.086CC..EExtended strand (participates in β ladder)trans-124.8141.6178.6-68.2-89.4000111.3S340 L341 V466 I503 W658 V659 V661 F684S340-Y505 WeakPolarHBondContact O-CA 3.45Å; L341-Y505 HydrophobicContact CB-CD1 4.46Å; L341-Y505 HydrophobicContact CB-CE1 4.17Å; L341-Y505 HydrophobicContact CD1-CE1 4.08Å; V466-Y505 HydrophobicContact CG1-CD1 3.94Å; V466-Y505 HydrophobicContact CG1-CE1 3.51Å; V466-Y505 HydrophobicContact CG1-CE2 4.39Å; I503-Y505 HydrophobicContact CB-CE2 4.17Å; I503-Y505 HydrophobicContact CG2-CD2 3.99Å; I503-Y505 HydrophobicContact CG2-CE2 3.29Å; Y505-W658 WeakPolarHBondContact O-CA 3.4Å; Y505-V659 PolarHBondContact N-O 2.9Å; Y505-V659 PolarHBondContact O-N 3.13Å; Y505-V661 HydrophobicContact CD2-CG2 4.39Å; Y505-V661 HydrophobicContact CE2-CG2 3.97Å; Y505-F684 HydrophobicContact CD1-CE1 4.38Å; Y505-F684 AromaticContact CD2-CE1 3.78Å; Y505-F684 HydrophobicContact CD2-CE1 3.78Å; Y505-F684 HydrophobicContact CE2-CE1 4.41Å; Y505-F684 AromaticContact CG-CE1 3.75Å; Y505-F684 HydrophobicContact CG-CE1 3.75Å; Y505-F684 HydrophobicContact CG-CZ 4.34Å
506K98.9Very high98.1Very high9 Ų916.1 Ų16.14%0.0399%0.086CC..EExtended strand (participates in β ladder)trans-93.5132164.3-178.2-173.7176.6-169.70108.3E338 I339 S340 Q342 V656 W658E338-K506 IonicContact OE1-NZ 3.26Å; E338-K506 WeakPolarHBondContact OE2-CE 3.36Å; E338-K506 IonicContact OE2-NZ 3.83Å; E338-K506 PolarHBondContact OE2-NZ 2.9Å; I339-K506 CarbonylContact C-O 3.12Å; I339-K506 VanDerWaalsContact CA-O 3.31Å; I339-K506 WeakPolarHBondContact CA-O 3.4Å; S340-K506 PolarHBondContact N-O 3.15Å; S340-K506 PolarHBondContact O-N 3.37Å; Q342-K506 HydrophobicContact CG-CB 3.78Å; K506-V656 HydrophobicContact CD-CG1 4.4Å; K506-V656 HydrophobicContact CG-CG1 3.57Å; K506-W658 HydrophobicContact CB-CE3 3.92Å; K506-W658 HydrophobicContact CB-CH2 4.34Å; K506-W658 HydrophobicContact CB-CZ3 3.69Å; K506-W658 HydrophobicContact CD-CH2 3.98Å; K506-W658 HydrophobicContact CD-CZ3 4.15Å; K506-W658 HydrophobicContact CG-CE3 4.17Å; K506-W658 HydrophobicContact CG-CH2 3.96Å; K506-W658 HydrophobicContact CG-CZ2 4.43Å; K506-W658 HydrophobicContact CG-CZ3 3.82Å
507V98.9Very high98.2Very high0 Ų016.2 Ų16.20%09%0.086CC..EExtended strand (participates in β ladder)trans-132.586.8-179.2-166.80000108.1I339 L509 A657 V659 F684 L686I339-V507 HydrophobicContact CG1-CG1 4.26Å; I339-V507 HydrophobicContact CG2-CG2 4.28Å; V507-L509 HydrophobicContact CG1-CD2 3.89Å; V507-L509 HydrophobicContact CG1-CG 4.02Å; V507-L509 PolarHBondContact O-N 3.39Å; V507-A657 WeakPolarHBondContact CA-O 3.45Å; V507-A657 HydrophobicContact CB-CB 4.15Å; V507-A657 PolarHBondContact N-O 2.83Å; V507-A657 PolarHBondContact O-N 2.96Å; V507-V659 HydrophobicContact CG2-CB 4.42Å; V507-V659 HydrophobicContact CG2-CG2 3.77Å; V507-F684 HydrophobicContact CG2-CE1 4.46Å; V507-F684 HydrophobicContact CG2-CE2 3.83Å; V507-F684 HydrophobicContact CG2-CZ 3.54Å; V507-L686 HydrophobicContact CG1-CD1 3.98Å; V507-L686 HydrophobicContact CG1-CD2 4.06Å
508D98.9Very high98.2Very high0 Ų016.2 Ų16.20%09%0.086CC..EExtended strand (participates in β ladder)trans-83.996-179.6-173.5-0.1000109.7K77 A336 Y337 E338 H617 V656K77-D508 WeakPolarHBondContact CD-OD2 3.3Å; K77-D508 WeakPolarHBondContact CE-OD2 3.41Å; K77-D508 IonicContact NZ-OD1 3.14Å; K77-D508 PolarHBondContact NZ-OD1 3.39Å; K77-D508 IonicContact NZ-OD2 2.75Å; K77-D508 PolarHBondContact NZ-OD2 2.97Å; A336-D508 CarbonylContact C-O 3.46Å; A336-D508 VanDerWaalsContact CA-O 3.24Å; A336-D508 WeakPolarHBondContact CA-O 3.32Å; A336-D508 WeakPolarHBondContact CB-O 3.37Å; Y337-D508 WeakPolarHBondContact CD1-OD2 3.33Å; Y337-D508 PolarHBondContact N-O 2.88Å; E338-D508 HydrophobicContact CB-CB 4.02Å; E338-D508 PolarHBondContact O-N 2.79Å; D508-H617 IonicContact OD2-CD2 3.83Å; D508-V656 HydrophobicContact CB-CG1 4.5Å; D508-V656 HydrophobicContact CB-CG2 4.21Å
509L98.8Very high98.2Very high0 Ų014.3 Ų14.30%08%0.077CC..EExtended strand (participates in β ladder)trans-90.9122.1-174.4-65.8175.3000110.2A336 V507 I511 N516 F568 I585 L655 L686A336-L509 HydrophobicContact CB-CD2 4.07Å; V507-L509 HydrophobicContact CG1-CD2 3.89Å; V507-L509 HydrophobicContact CG1-CG 4.02Å; V507-L509 PolarHBondContact O-N 3.39Å; L509-I511 HydrophobicContact CB-CD1 4.13Å; L509-I511 HydrophobicContact CB-CG1 4.31Å; L509-I511 HydrophobicContact CD2-CD1 4.34Å; L509-N516 PolarHBondContact O-OD1 2.91Å; L509-N516 VanDerWaalsContact O-OD1 3.12Å; L509-F568 HydrophobicContact CD1-CB 3.86Å; L509-F568 HydrophobicContact CD1-CD1 4.04Å; L509-F568 HydrophobicContact CD1-CD2 3.57Å; L509-F568 HydrophobicContact CD1-CE1 4.49Å; L509-F568 HydrophobicContact CD1-CE2 4.09Å; L509-F568 HydrophobicContact CD1-CG 3.55Å; L509-I585 HydrophobicContact CD1-CD1 4.41Å; L509-L655 PolarHBondContact N-O 3.3Å; L509-L686 HydrophobicContact CD2-CD1 3.92Å; L509-L686 HydrophobicContact CD2-CD2 4.46Å
510D98.4Very high98.2Very high0 Ų015 Ų150%08%0.08CC..  trans-116.966.9175.4-861.1000108.4K77 R334 I335 V512 G513K77-D510 WeakPolarHBondContact CE-OD2 3.46Å; K77-D510 IonicContact NZ-OD1 3.33Å; K77-D510 PolarHBondContact NZ-OD1 3.37Å; K77-D510 IonicContact NZ-OD2 3.45Å; K77-D510 PolarHBondContact NZ-OD2 3.03Å; R334-D510 HydrophobicContact CG-CB 4.17Å; R334-D510 VanDerWaalsContact O-O 3.07Å; I335-D510 CarbonylContact O-C 3.41Å; I335-D510 PolarHBondContact O-N 2.76Å; D510-V512 PolarHBondContact O-N 2.89Å; D510-G513 CarbonylContact C-O 3.56Å; D510-G513 VanDerWaalsContact CA-O 3.28Å; D510-G513 WeakPolarHBondContact CA-O 3.29Å; D510-G513 PolarHBondContact O-N 3.43Å
511I98.2Very high98.2Very high0 Ų014.2 Ų14.20%08%0.076CC..THydrogen-bonded Turntrans-6599.7-175.1-52.1-55000109.8I335 L509 G513 N516 F568 N570 Y583 F691I335-I511 HydrophobicContact CG2-CD1 4.23Å; I335-I511 WeakPolarHBondContact O-CD1 3.45Å; L509-I511 HydrophobicContact CB-CD1 4.13Å; L509-I511 HydrophobicContact CB-CG1 4.31Å; L509-I511 HydrophobicContact CD2-CD1 4.34Å; I511-G513 PolarHBondContact N-O 2.87Å; I511-G513 PolarHBondContact O-N 3.35Å; I511-N516 WeakPolarHBondContact CB-OD1 3.05Å; I511-N516 WeakPolarHBondContact CG1-OD1 3.02Å; I511-N516 PolarHBondContact N-OD1 2.85Å; I511-N516 PolarHBondContact O-ND2 2.8Å; I511-F568 HydrophobicContact CG1-CB 4.39Å; I511-N570 HydrophobicContact CG2-CB 4.47Å; I511-N570 WeakPolarHBondContact O-CB 3.19Å; I511-N570 PolarHBondContact O-ND2 2.86Å; I511-Y583 HydrophobicContact CD1-CD2 3.9Å; I511-Y583 HydrophobicContact CD1-CG 4.08Å; I511-F691 HydrophobicContact CG2-CD2 3.86Å; I511-F691 HydrophobicContact CG2-CE2 3.79Å
512V94.4Very high98Very high40 Ų4015.7 Ų15.724%0.2428%0.084CC..THydrogen-bonded Turntrans51.843.9-174.2-161.10000111.2R334 D510 N570 E573 K581 F691R334-V512 PolarHBondContact O-N 2.88Å; D510-V512 PolarHBondContact O-N 2.89Å; V512-N570 PolarHBondContact O-ND2 2.94Å; V512-N570 VanDerWaalsContact O-ND2 3.16Å; V512-E573 HydrophobicContact CB-CG 4.17Å; V512-E573 HydrophobicContact CG1-CG 3.93Å; V512-K581 HydrophobicContact CG2-CD 3.8Å; V512-F691 HydrophobicContact CG2-CD2 4.36Å; V512-F691 HydrophobicContact CG2-CE2 3.44Å; V512-F691 VanDerWaalsContact CG2-CE2 3.44Å; V512-F691 HydrophobicContact CG2-CZ 3.71Å
513G94.7Very high97.8Very high26 Ų2619.5 Ų19.527%0.26810%0.103SC..SBendtrans109.8177.5-17700000113.1D510 I511 N516D510-G513 CarbonylContact C-O 3.56Å; D510-G513 VanDerWaalsContact CA-O 3.28Å; D510-G513 WeakPolarHBondContact CA-O 3.29Å; D510-G513 PolarHBondContact O-N 3.43Å; I511-G513 PolarHBondContact N-O 2.87Å; I511-G513 PolarHBondContact O-N 3.35Å; G513-N516 PolarHBondContact O-ND2 2.87Å
514R97.1Very high97.6Very high98 Ų9825.7 Ų25.737%0.3713%0.13SC..SBendtrans-80-24.1-167.4-67.3-176.9-67.5173.48114.5L81 N516 Q653 D654L81-R514 HydrophobicContact CD1-CG 4.02Å; R514-N516 PolarHBondContact O-N 2.82Å; R514-Q653 CarbonylContact O-C 3.44Å; R514-D654 HydrophobicContact CB-CB 4.18Å; R514-D654 WeakPolarHBondContact CD-OD2 3.48Å; R514-D654 WeakPolarHBondContact O-CA 3.44Å; R514-D654 PolarHBondContact O-N 3.45Å
515D98Very high97.5Very high86 Ų8633.3 Ų33.346%0.4616%0.16SC..  trans-83.992.5-171.7-57.8-43.3000109.6P571 N652D515-P571 WeakPolarHBondContact O-CD 3.43Å; D515-N652 WeakPolarHBondContact CB-OD1 3.34Å
516N98.8Very high97.3Very high0 Ų035.2 Ų35.20%017%0.172CC..BIsolated β-bridgetrans-121.2158.3-174.6-67.2176.9000111.6L509 I511 G513 R514 Y569 N652 Q653 L655L509-N516 PolarHBondContact O-OD1 2.91Å; L509-N516 VanDerWaalsContact O-OD1 3.12Å; I511-N516 WeakPolarHBondContact CB-OD1 3.05Å; I511-N516 WeakPolarHBondContact CG1-OD1 3.02Å; I511-N516 PolarHBondContact N-OD1 2.85Å; I511-N516 PolarHBondContact O-ND2 2.8Å; G513-N516 PolarHBondContact O-ND2 2.87Å; R514-N516 PolarHBondContact O-N 2.82Å; N516-Y569 CarbonylContact C-O 3.08Å; N516-Y569 WeakPolarHBondContact CA-O 3.35Å; N516-N652 CarbonylContact O-C 3.53Å; N516-N652 WeakPolarHBondContact O-CA 3.15Å; N516-N652 PolarHBondContact O-N 3.46Å; N516-Q653 PolarHBondContact N-O 3.28Å; N516-Q653 PolarHBondContact O-N 2.77Å; N516-Q653 VanDerWaalsContact O-O 3.11Å; N516-L655 HydrophobicContact CB-CD1 4.38Å; N516-L655 HydrophobicContact CB-CG 4.4Å
517S98.8Very high97.3Very high2 Ų240 Ų401%0.01420%0.198CC..EExtended strand (participates in β ladder)trans-127.3160.9174.2-73.40000109.9F568 Y569 N652S517-F568 WeakPolarHBondContact O-CA 3.49Å; S517-Y569 VanDerWaalsContact CB-CZ 3.49Å; S517-Y569 PolarHBondContact N-O 2.78Å; S517-Y569 WeakPolarHBondContact O-CD1 3.49Å; S517-Y569 PolarHBondContact O-N 2.67Å; S517-N652 PolarHBondContact OG-N 2.9Å
518F98.9Very high97.1Very high0 Ų043.3 Ų43.30%021%0.213CC..EExtended strand (participates in β ladder)trans-121.7132.6-178.2178.3-113000111.8T520 H548 A554 F556 V566 H567 F568 L612 V614 I650 L655F518-T520 HydrophobicContact CE1-CG2 4.15Å; F518-T520 HydrophobicContact CZ-CG2 3.86Å; F518-H548 HydrophobicContact CD1-CB 3.72Å; F518-H548 AromaticContact CD1-CD2 3.91Å; F518-H548 AromaticContact CD1-CG 3.96Å; F518-H548 HydrophobicContact CE1-CB 4.24Å; F518-H548 AromaticContact CE1-CD2 3.68Å; F518-H548 AromaticContact CE1-CG 3.98Å; F518-H548 PolarHBondContact O-N 2.7Å; F518-A554 HydrophobicContact CD1-CB 3.61Å; F518-A554 HydrophobicContact CE1-CB 3.79Å; F518-F556 AromaticContact CE1-CE2 3.72Å; F518-F556 HydrophobicContact CE1-CE2 3.72Å; F518-F556 AromaticContact CE1-CZ 3.93Å; F518-F556 HydrophobicContact CE1-CZ 3.93Å; F518-F556 AromaticContact CZ-CE2 3.83Å; F518-F556 HydrophobicContact CZ-CE2 3.83Å; F518-F556 HydrophobicContact CZ-CZ 4.2Å; F518-V566 HydrophobicContact CE2-CB 4.31Å; F518-V566 HydrophobicContact CE2-CG1 3.46Å; F518-V566 VanDerWaalsContact CE2-CG1 3.46Å; F518-V566 HydrophobicContact CZ-CB 4.5Å; F518-V566 HydrophobicContact CZ-CG1 3.8Å; F518-H567 VanDerWaalsContact CD2-O 3.29Å; F518-H567 WeakPolarHBondContact CD2-O 3.33Å; F518-F568 HydrophobicContact CB-CE1 4.46Å; F518-F568 HydrophobicContact CD2-CD1 4.21Å; F518-F568 AromaticContact CD2-CD2 3.93Å; F518-F568 HydrophobicContact CD2-CD2 3.93Å; F518-F568 HydrophobicContact CD2-CE1 4.01Å; F518-F568 AromaticContact CD2-CE2 3.7Å; F518-F568 HydrophobicContact CD2-CE2 3.7Å; F518-F568 HydrophobicContact CD2-CG 4.17Å; F518-F568 AromaticContact CD2-CZ 3.74Å; F518-F568 HydrophobicContact CD2-CZ 3.74Å; F518-F568 HydrophobicContact CE2-CD2 4.25Å; F518-F568 AromaticContact CE2-CE2 3.81Å; F518-F568 HydrophobicContact CE2-CE2 3.81Å; F518-F568 HydrophobicContact CE2-CZ 4.13Å; F518-F568 HydrophobicContact CG-CE1 4.47Å; F518-F568 HydrophobicContact CG-CZ 4.46Å; F518-L612 HydrophobicContact CZ-CD2 4.15Å; F518-V614 HydrophobicContact CD1-CG2 4.02Å; F518-V614 HydrophobicContact CD2-CG2 4.3Å; F518-V614 HydrophobicContact CE1-CG2 4.18Å; F518-V614 HydrophobicContact CE2-CG2 4.43Å; F518-V614 HydrophobicContact CG-CG2 4.12Å; F518-V614 HydrophobicContact CZ-CG2 4.39Å; F518-I650 HydrophobicContact CB-CD1 4.37Å; F518-L655 HydrophobicContact CB-CD1 4.16Å
519E98.7Very high97.1Very high9 Ų946.7 Ų46.74%0.04223%0.233CC..EExtended strand (participates in β ladder)trans-135.2158.9172.471.1177.4165.800111.8I521 R545 T546 H567 Y569E519-I521 HydrophobicContact CG-CG1 4.32Å; E519-R545 IonicContact OE1-CZ 2.62Å; E519-R545 IonicContact OE1-NH1 3.55Å; E519-R545 PolarHBondContact OE1-NH1 2.83Å; E519-R545 IonicContact OE2-CZ 3.96Å; E519-R545 IonicContact OE2-NH1 2.93Å; E519-R545 PolarHBondContact OE2-NH1 2.79Å; E519-T546 CarbonylContact C-O 3.46Å; E519-T546 VanDerWaalsContact CA-O 3.23Å; E519-T546 WeakPolarHBondContact CA-O 3.33Å; E519-T546 WeakPolarHBondContact CB-O 3.09Å; E519-H567 HydrophobicContact CG-CB 3.98Å; E519-H567 PolarHBondContact N-O 2.9Å; E519-H567 PolarHBondContact O-N 2.86Å; E519-H567 IonicContact OE1-CE1 3.96Å; E519-H567 IonicContact OE1-CG 3.69Å; E519-H567 IonicContact OE1-ND1 3.79Å; E519-H567 PolarHBondContact OE1-ND1 2.92Å; E519-Y569 HydrophobicContact CB-CE1 3.99Å; E519-Y569 HydrophobicContact CG-CD1 4.06Å; E519-Y569 HydrophobicContact CG-CE1 3.86Å
520T98.6Very high97Very high14 Ų1447 Ų479%0.08624%0.235CC..EExtended strand (participates in β ladder)trans-111.7147.2165.356.50000110.8F518 R545 T546 H548 F556 P563 Y565F518-T520 HydrophobicContact CE1-CG2 4.15Å; F518-T520 HydrophobicContact CZ-CG2 3.86Å; T520-R545 WeakPolarHBondContact O-CA 3.38Å; T520-T546 PolarHBondContact N-O 3.24Å; T520-T546 PolarHBondContact O-N 3.36Å; T520-H548 VanDerWaalsContact CG2-NE2 3.31Å; T520-H548 WeakPolarHBondContact CG2-NE2 3.47Å; T520-H548 PolarHBondContact OG1-NE2 2.97Å; T520-F556 HydrophobicContact CG2-CE1 4.29Å; T520-F556 HydrophobicContact CG2-CE2 4.46Å; T520-F556 HydrophobicContact CG2-CZ 3.65Å; T520-P563 HydrophobicContact CG2-CB 3.58Å; T520-P563 HydrophobicContact CG2-CG 3.47Å; T520-P563 VanDerWaalsContact CG2-CG 3.47Å; T520-Y565 VanDerWaalsContact CA-O 3.25Å; T520-Y565 WeakPolarHBondContact CA-O 3.37Å
521I97.6Very high96.9Very high4 Ų451.7 Ų51.72%0.02127%0.266CS..EExtended strand (participates in β ladder)trans-125.9127.9179.2-42.4178.4000109.5E519 L543 H544 R545 Y565 F689E519-I521 HydrophobicContact CG-CG1 4.32Å; I521-L543 HydrophobicContact CG2-CD1 3.3Å; I521-L543 HydrophobicContact CG2-CD2 4.27Å; I521-L543 HydrophobicContact CG2-CG 3.73Å; I521-H544 WeakPolarHBondContact CA-O 3.44Å; I521-R545 HydrophobicContact CG1-CG 4.22Å; I521-R545 HydrophobicContact CG2-CG 4.16Å; I521-Y565 HydrophobicContact CB-CG 4.26Å; I521-Y565 PolarHBondContact N-O 3.26Å; I521-Y565 WeakPolarHBondContact O-CB 3.38Å; I521-Y565 PolarHBondContact O-N 2.76Å; I521-F689 HydrophobicContact CD1-CE1 3.86Å; I521-F689 HydrophobicContact CD1-CZ 4.23Å
522D95.5Very high96.9Very high33 Ų3361.3 Ų61.318%0.17630%0.302CS..EExtended strand (participates in β ladder)trans-136.6174.4176.1-153.8-14.1000110.3H544 K561 R564D522-H544 PolarHBondContact N-O 3.41Å; D522-H544 PolarHBondContact O-N 3.31Å; D522-K561 WeakPolarHBondContact OD2-CE 3.45Å; D522-K561 IonicContact OD2-NZ 2.73Å; D522-K561 PolarHBondContact OD2-NZ 2.57Å; D522-R564 WeakPolarHBondContact OD1-CD 3.47Å; D522-R564 IonicContact OD1-NE 3.61Å
523L94.7Very high97Very high79 Ų7961 Ų6141%0.41430%0.302SS..EExtended strand (participates in β ladder)trans-98.1136.1172.5-59.4179000109.7
524K94.3Very high96.9Very high134 Ų13464.4 Ų64.458%0.58332%0.319SS*.EExtended strand (participates in β ladder)trans-117.9130.1166.5-173175.5-179177.70109.1K542 H544K524-K542 PolarHBondContact N-O 3.44Å; K524-K542 PolarHBondContact O-N 3.09Å; K524-H544 HydrophobicContact CB-CB 4.17Å
525Y96Very high96.9Very high160 Ų16067 Ų6763%0.62734%0.34SS*.EExtended strand (participates in β ladder)trans-72.3136.5173.2-66.5-74.8000110.5V539 Q540 S541Y525-V539 HydrophobicContact CD1-CG1 4.2Å; Y525-Q540 CarbonylContact C-O 3.54Å; Y525-Q540 WeakPolarHBondContact CA-O 3.34Å; Y525-S541 WeakPolarHBondContact CE1-OG 2.95Å
526V96.4Very high96.9Very high46 Ų4667 Ų6728%0.27934%0.34SS..EExtended strand (participates in β ladder)trans-117.1142169.9-62.90000108.5F528 V539 Q540 K542V526-F528 HydrophobicContact CG2-CD1 4.18Å; V526-F528 HydrophobicContact CG2-CE1 4.32Å; V526-V539 WeakPolarHBondContact O-CA 3.37Å; V526-Q540 HydrophobicContact CG2-CG 3.83Å; V526-Q540 PolarHBondContact N-O 3.5Å; V526-Q540 PolarHBondContact O-N 2.95Å; V526-K542 HydrophobicContact CG1-CB 3.93Å; V526-K542 HydrophobicContact CG1-CD 4.08Å; V526-K542 HydrophobicContact CG2-CB 4.37Å
527N97.1Very high96.8Very high109 Ų10973.7 Ų73.758%0.58337%0.37SS*.EExtended strand (participates in β ladder)trans-118.7125.2173.6-175.24.1000107.9I538 V539N527-I538 WeakPolarHBondContact CA-O 3.11Å; N527-V539 HydrophobicContact CB-CG2 4.16Å
528F96.4Very high96.7Very high69 Ų6975.6 Ų75.630%0.30338%0.379SS..EExtended strand (participates in β ladder)trans-148.2155-178.764.5-73.2000110.5V526 N530 P531 F537 I538 Q540V526-F528 HydrophobicContact CG2-CD1 4.18Å; V526-F528 HydrophobicContact CG2-CE1 4.32Å; F528-N530 PolarHBondContact O-N 2.96Å; F528-P531 HydrophobicContact CD2-CG 4.33Å; F528-P531 HydrophobicContact CE2-CG 3.9Å; F528-F537 WeakPolarHBondContact O-CA 3.45Å; F528-I538 WeakPolarHBondContact CD1-O 3.47Å; F528-I538 HydrophobicContact CE1-CB 4.11Å; F528-I538 HydrophobicContact CE1-CG2 3.97Å; F528-I538 HydrophobicContact CZ-CB 4.14Å; F528-I538 HydrophobicContact CZ-CG2 4.11Å; F528-I538 PolarHBondContact N-O 3Å; F528-I538 VanDerWaalsContact N-O 3.16Å; F528-I538 PolarHBondContact O-N 3.38Å; F528-Q540 HydrophobicContact CE1-CG 3.89Å
529T97.5Very high96.7Very high71 Ų7180.2 Ų80.244%0.43641%0.407SS..EExtended strand (participates in β ladder)trans-57.9131.5173.5-57.70000109.8P531 P534T529-P531 WeakPolarHBondContact O-CD 3.39Å; T529-P534 HydrophobicContact CG2-CB 4.39Å; T529-P534 VanDerWaalsContact CG2-O 3.24Å; T529-P534 WeakPolarHBondContact CG2-O 3.27Å
530N97.5Very high96.6Very high6 Ų684.4 Ų84.43%0.03243%0.427CS..  trans-63.2114.7179.1-180-10.1000109.9F528 W532 S533 N536 I538F528-N530 PolarHBondContact O-N 2.96Å; N530-W532 VanDerWaalsContact ND2-CE2 3.29Å; N530-W532 VanDerWaalsContact ND2-CH2 3.34Å; N530-W532 WeakPolarHBondContact ND2-CH2 3.04Å; N530-W532 WeakPolarHBondContact ND2-CZ2 3.44Å; N530-W532 PolarHBondContact O-N 3.2Å; N530-W532 VanDerWaalsContact O-N 3.14Å; N530-W532 PolarHBondContact OD1-N 2.8Å; N530-W532 VanDerWaalsContact OD1-N 3.12Å; N530-W532 PolarHBondContact OD1-NE1 2.92Å; N530-S533 WeakPolarHBondContact CB-O 3.3Å; N530-S533 CarbonylContact O-C 3.28Å; N530-S533 PolarHBondContact O-N 3.05Å; N530-S533 PolarHBondContact OD1-N 2.9Å; N530-N536 HydrophobicContact CB-CB 4.19Å; N530-N536 WeakPolarHBondContact CB-O 3.27Å; N530-N536 PolarHBondContact N-O 3.04Å; N530-I538 HydrophobicContact CB-CD1 3.91Å; N530-I538 HydrophobicContact CB-CG1 3.96Å; N530-I538 VanDerWaalsContact CG-CD1 3.48Å
531P96.8Very high96.5Very high100 Ų10086.3 Ų86.365%0.64944%0.441SS*.THydrogen-bonded Turntrans-63.8-23.1-173.9-23.334.8000114.3F528 T529F528-P531 HydrophobicContact CD2-CG 4.33Å; F528-P531 HydrophobicContact CE2-CG 3.9Å; T529-P531 WeakPolarHBondContact O-CD 3.39Å
532W96.6Very high96.4Very high202 Ų20292.7 Ų92.777%0.76547%0.468SS*.THydrogen-bonded Turntrans-104.61.2178.252.1-93.8000112.8N530 I538N530-W532 VanDerWaalsContact ND2-CE2 3.29Å; N530-W532 VanDerWaalsContact ND2-CH2 3.34Å; N530-W532 WeakPolarHBondContact ND2-CH2 3.04Å; N530-W532 WeakPolarHBondContact ND2-CZ2 3.44Å; N530-W532 PolarHBondContact O-N 3.2Å; N530-W532 VanDerWaalsContact O-N 3.14Å; N530-W532 PolarHBondContact OD1-N 2.8Å; N530-W532 VanDerWaalsContact OD1-N 3.12Å; N530-W532 PolarHBondContact OD1-NE1 2.92Å; W532-I538 HydrophobicContact CZ2-CD1 4.21Å
533S97.1Very high96.4Very high34 Ų3495.9 Ų95.924%0.23849%0.485CS..SBendtrans-152.779.7173.3-166.80000111N530 N535 N536N530-S533 WeakPolarHBondContact CB-O 3.3Å; N530-S533 CarbonylContact O-C 3.28Å; N530-S533 PolarHBondContact O-N 3.05Å; N530-S533 PolarHBondContact OD1-N 2.9Å; S533-N535 PolarHBondContact O-N 2.9Å; S533-N536 PolarHBondContact O-N 3.49Å; S533-N536 PolarHBondContact OG-ND2 2.96Å
534P93.4Very high96.5Very high96 Ų9696.5 Ų96.562%0.62349%0.485SS*.THydrogen-bonded Turntrans-60-16.2-165.3-28.236.4000117T529 N536T529-P534 HydrophobicContact CG2-CB 4.39Å; T529-P534 VanDerWaalsContact CG2-O 3.24Å; T529-P534 WeakPolarHBondContact CG2-O 3.27Å; P534-N536 VanDerWaalsContact C-N 3.29Å
535N96.8Very high96.7Very high152 Ų15294.6 Ų94.681%0.81347%0.474SS*.THydrogen-bonded Turntrans-83.4-4.6175.1-65.4-24.7000113.3S533S533-N535 PolarHBondContact O-N 2.9Å
536N97.6Very high96.8Very high87 Ų8789.7 Ų89.747%0.46546%0.461SS..SBendtrans-115.5160.2-178.1-66.9-72.5000110.8N530 S533 P534N530-N536 HydrophobicContact CB-CB 4.19Å; N530-N536 WeakPolarHBondContact CB-O 3.27Å; N530-N536 PolarHBondContact N-O 3.04Å; S533-N536 PolarHBondContact O-N 3.49Å; S533-N536 PolarHBondContact OG-ND2 2.96Å; P534-N536 VanDerWaalsContact C-N 3.29Å
537F96.7Very high96.9Very high141 Ų14191.1 Ų91.162%0.61847%0.465SS*.EExtended strand (participates in β ladder)trans-116.9147.3175.7-63.7-86.7000110.3F528F528-F537 WeakPolarHBondContact O-CA 3.45Å
538I97.4Very high96.9Very high42 Ų4286.9 Ų86.922%0.21544%0.442CS..EExtended strand (participates in β ladder)trans-115.7126.7171.5-69.1171.8000108.4N527 F528 N530 W532 Q540N527-I538 WeakPolarHBondContact CA-O 3.11Å; F528-I538 WeakPolarHBondContact CD1-O 3.47Å; F528-I538 HydrophobicContact CE1-CB 4.11Å; F528-I538 HydrophobicContact CE1-CG2 3.97Å; F528-I538 HydrophobicContact CZ-CB 4.14Å; F528-I538 HydrophobicContact CZ-CG2 4.11Å; F528-I538 PolarHBondContact N-O 3Å; F528-I538 VanDerWaalsContact N-O 3.16Å; F528-I538 PolarHBondContact O-N 3.38Å; N530-I538 HydrophobicContact CB-CD1 3.91Å; N530-I538 HydrophobicContact CB-CG1 3.96Å; N530-I538 VanDerWaalsContact CG-CD1 3.48Å; W532-I538 HydrophobicContact CZ2-CD1 4.21Å; I538-Q540 HydrophobicContact CG2-CB 4.18Å
539V97.4Very high97.1Very high96 Ų9689.4 Ų89.458%0.58245%0.453SS*.EExtended strand (participates in β ladder)trans-100121.4165.2-177.90000108Y525 V526 N527Y525-V539 HydrophobicContact CD1-CG1 4.2Å; V526-V539 WeakPolarHBondContact O-CA 3.37Å; N527-V539 HydrophobicContact CB-CG2 4.16Å
540Q96.6Very high97.1Very high98 Ų9888.1 Ų88.146%0.45844%0.444SS..EExtended strand (participates in β ladder)trans-142.6163.2177.476.5-174.43.900111.8Y525 V526 F528 I538Y525-Q540 CarbonylContact C-O 3.54Å; Y525-Q540 WeakPolarHBondContact CA-O 3.34Å; V526-Q540 HydrophobicContact CG2-CG 3.83Å; V526-Q540 PolarHBondContact N-O 3.5Å; V526-Q540 PolarHBondContact O-N 2.95Å; F528-Q540 HydrophobicContact CE1-CG 3.89Å; I538-Q540 HydrophobicContact CG2-CB 4.18Å
541S96.7Very high97.2Very high54 Ų5487.8 Ų87.838%0.37844%0.443SS..EExtended strand (participates in β ladder)trans-79.5140.7174.7-560000111.6Y525Y525-S541 WeakPolarHBondContact CE1-OG 2.95Å
542K96Very high97.3Very high137 Ų13789.8 Ų89.860%0.59644%0.438SS*.EExtended strand (participates in β ladder)trans-122.2142.2169.1-170.2174.6-177.6177.50109.2K524 V526 H544K524-K542 PolarHBondContact N-O 3.44Å; K524-K542 PolarHBondContact O-N 3.09Å; V526-K542 HydrophobicContact CG1-CB 3.93Å; V526-K542 HydrophobicContact CG1-CD 4.08Å; V526-K542 HydrophobicContact CG2-CB 4.37Å; K542-H544 PolarHBondContact O-N 2.77Å
543L96.4Very high97.3Very high100 Ų10082.5 Ų82.552%0.52442%0.417SS..EExtended strand (participates in β ladder)trans-63.6131.1175.1-161.670.5000110.1I521 R545I521-L543 HydrophobicContact CG2-CD1 3.3Å; I521-L543 HydrophobicContact CG2-CD2 4.27Å; I521-L543 HydrophobicContact CG2-CG 3.73Å; L543-R545 HydrophobicContact CD2-CG 4.34Å; L543-R545 HydrophobicContact CG-CG 4.47Å
544H96.5Very high97.4Very high92 Ų9280.9 Ų80.943%0.42641%0.406SS..EExtended strand (participates in β ladder)trans-123.4123.5173.8-173.156.1000109.1I521 D522 K524 K542I521-H544 WeakPolarHBondContact CA-O 3.44Å; D522-H544 PolarHBondContact N-O 3.41Å; D522-H544 PolarHBondContact O-N 3.31Å; K524-H544 HydrophobicContact CB-CB 4.17Å; K542-H544 PolarHBondContact O-N 2.77Å
545R97.1Very high97.6Very high94 Ų9477.1 Ų77.136%0.35538%0.383SS..EExtended strand (participates in β ladder)trans-114.8135.3-178.1-66.8172.4169.5-99.6-0.9109.1E519 T520 I521 L543E519-R545 IonicContact OE1-CZ 2.62Å; E519-R545 IonicContact OE1-NH1 3.55Å; E519-R545 PolarHBondContact OE1-NH1 2.83Å; E519-R545 IonicContact OE2-CZ 3.96Å; E519-R545 IonicContact OE2-NH1 2.93Å; E519-R545 PolarHBondContact OE2-NH1 2.79Å; T520-R545 WeakPolarHBondContact O-CA 3.38Å; I521-R545 HydrophobicContact CG1-CG 4.22Å; I521-R545 HydrophobicContact CG2-CG 4.16Å; L543-R545 HydrophobicContact CD2-CG 4.34Å; L543-R545 HydrophobicContact CG-CG 4.47Å
546T98.3Very high97.7Very high57 Ų5771.4 Ų71.435%0.3535%0.351SS..EExtended strand (participates in β ladder)trans-125.9108176.9-56.50000108.5E519 T520 H548E519-T546 CarbonylContact C-O 3.46Å; E519-T546 VanDerWaalsContact CA-O 3.23Å; E519-T546 WeakPolarHBondContact CA-O 3.33Å; E519-T546 WeakPolarHBondContact CB-O 3.09Å; T520-T546 PolarHBondContact N-O 3.24Å; T520-T546 PolarHBondContact O-N 3.36Å; T546-H548 PolarHBondContact O-CD2 2.76Å; T546-H548 VanDerWaalsContact O-CD2 3.26Å
547E98.4Very high97.7Very high77 Ų7772.6 Ų72.636%0.3635%0.349SS..EExtended strand (participates in β ladder)trans-74.4131169.8-176.9-176.7-127.600109.5K549 Y569E547-K549 HydrophobicContact CG-CG 4.49Å; E547-K549 VanDerWaalsContact OE2-CE 3.24Å; E547-K549 WeakPolarHBondContact OE2-CE 3.49Å; E547-Y569 PolarHBondContact OE1-OH 3.45Å
548H98.6Very high97.6Very high20 Ų2067.4 Ų67.49%0.09333%0.326CS..EExtended strand (participates in β ladder)trans-100.7120.7176.6-68.6-92.9000108.7F518 T520 T546 S553 A554 F556 I650F518-H548 HydrophobicContact CD1-CB 3.72Å; F518-H548 AromaticContact CD1-CD2 3.91Å; F518-H548 AromaticContact CD1-CG 3.96Å; F518-H548 HydrophobicContact CE1-CB 4.24Å; F518-H548 AromaticContact CE1-CD2 3.68Å; F518-H548 AromaticContact CE1-CG 3.98Å; F518-H548 PolarHBondContact O-N 2.7Å; T520-H548 VanDerWaalsContact CG2-NE2 3.31Å; T520-H548 WeakPolarHBondContact CG2-NE2 3.47Å; T520-H548 PolarHBondContact OG1-NE2 2.97Å; T546-H548 PolarHBondContact O-CD2 2.76Å; T546-H548 VanDerWaalsContact O-CD2 3.26Å; H548-S553 WeakPolarHBondContact CB-OG 3.35Å; H548-S553 PolarHBondContact CE1-O 3.31Å; H548-S553 VanDerWaalsContact CE1-O 3.26Å; H548-S553 PolarHBondContact ND1-O 2.86Å; H548-A554 HydrophobicContact CB-CB 4.05Å; H548-F556 AromaticContact CE1-CZ 3.8Å; H548-F556 AromaticContact NE2-CZ 3.89Å; H548-I650 HydrophobicContact CB-CD1 4.26Å; H548-I650 WeakPolarHBondContact O-CD1 3.42Å; H548-I650 WeakPolarHBondContact O-CG1 3.39Å
549K98.7Very high97.3Very high122 Ų12268.2 Ų68.253%0.5335%0.345SS..  trans-96.9-20.7-171.2-59.9-171.9177.3-175.80113.9E547 S553 N649 I650 V651E547-K549 HydrophobicContact CG-CG 4.49Å; E547-K549 VanDerWaalsContact OE2-CE 3.24Å; E547-K549 WeakPolarHBondContact OE2-CE 3.49Å; K549-S553 PolarHBondContact N-OG 2.71Å; K549-N649 WeakPolarHBondContact O-CA 3.4Å; K549-N649 PolarHBondContact O-OD1 3.24Å; K549-I650 VanDerWaalsContact C-CG1 3.49Å; K549-I650 WeakPolarHBondContact O-CG1 3.44Å; K549-I650 PolarHBondContact O-N 3.45Å; K549-V651 HydrophobicContact CB-CG2 3.88Å; K549-V651 HydrophobicContact CG-CG2 3.82Å
550T98.8Very high97.1Very high43 Ų4371.4 Ų71.426%0.26435%0.351SS..BIsolated β-bridgetrans-131.7157.5-179.376.30000112.5R552 S553 A554 N647 E648T550-R552 VanDerWaalsContact C-N 3.34Å; T550-R552 PolarHBondContact O-N 3.45Å; T550-S553 PolarHBondContact N-OG 3.07Å; T550-S553 WeakPolarHBondContact O-CB 3.21Å; T550-S553 PolarHBondContact O-N 3.39Å; T550-S553 PolarHBondContact O-OG 3.17Å; T550-A554 PolarHBondContact O-N 3.35Å; T550-N647 WeakPolarHBondContact CB-OD1 3.33Å; T550-N647 PolarHBondContact OG1-OD1 2.94Å; T550-E648 WeakPolarHBondContact CA-O 3.27Å
551E98.8Very high96.9Very high0 Ų074.3 Ų74.30%036%0.362CS..G310 helixtrans-54.8-46-179.4-60.2174.1137.800112.3S553 A554 A555 V614 T615 R616 N646 N647 E648 I650E551-S553 VanDerWaalsContact C-N 3.25Å; E551-S553 PolarHBondContact O-N 3.37Å; E551-A554 CarbonylContact O-C 3.48Å; E551-A554 WeakPolarHBondContact O-CA 3.47Å; E551-A554 PolarHBondContact O-N 3.11Å; E551-A555 PolarHBondContact O-N 3.29Å; E551-V614 WeakPolarHBondContact CA-O 3.2Å; E551-T615 WeakPolarHBondContact OE1-CA 3.46Å; E551-R616 PolarHBondContact OE1-N 2.77Å; E551-N646 VanDerWaalsContact OE2-CG 3.31Å; E551-N646 PolarHBondContact OE2-ND2 2.86Å; E551-N646 PolarHBondContact OE2-OD1 3.28Å; E551-N647 PolarHBondContact OE2-N 2.83Å; E551-E648 HydrophobicContact CG-CB 4.32Å; E551-E648 PolarHBondContact N-O 3.39Å; E551-E648 VanDerWaalsContact N-O 3.11Å; E551-E648 PolarHBondContact OE2-N 3.33Å; E551-I650 HydrophobicContact CG-CG2 3.55Å
552R98.4Very high96.8Very high142 Ų14274.8 Ų74.854%0.53636%0.358SS..G310 helixtrans-63-32.6178.4-65.9-179.8-178.3-174.83.8112.8T550 A554 A555 I644 R645 N647T550-R552 VanDerWaalsContact C-N 3.34Å; T550-R552 PolarHBondContact O-N 3.45Å; R552-A554 PolarHBondContact O-N 3.1Å; R552-A555 PolarHBondContact O-N 3.22Å; R552-I644 HydrophobicContact CG-CG2 3.91Å; R552-I644 WeakPolarHBondContact CG-O 3.35Å; R552-R645 PolarHBondContact NH2-O 3.15Å; R552-N647 WeakPolarHBondContact CB-OD1 3.2Å; R552-N647 HydrophobicContact CG-CB 3.85Å; R552-N647 WeakPolarHBondContact CG-OD1 3.27Å; R552-N647 PolarHBondContact N-OD1 3.3Å; R552-N647 VanDerWaalsContact N-OD1 3.15Å
553S98.3Very high96.6Very high48 Ų4869.1 Ų69.134%0.33634%0.335SS..G310 helixtrans-70-24.2176.975.80000111.9H548 K549 T550 E551H548-S553 WeakPolarHBondContact CB-OG 3.35Å; H548-S553 PolarHBondContact CE1-O 3.31Å; H548-S553 VanDerWaalsContact CE1-O 3.26Å; H548-S553 PolarHBondContact ND1-O 2.86Å; K549-S553 PolarHBondContact N-OG 2.71Å; T550-S553 PolarHBondContact N-OG 3.07Å; T550-S553 WeakPolarHBondContact O-CB 3.21Å; T550-S553 PolarHBondContact O-N 3.39Å; T550-S553 PolarHBondContact O-OG 3.17Å; E551-S553 VanDerWaalsContact C-N 3.25Å; E551-S553 PolarHBondContact O-N 3.37Å
554A98.4Very high96.5Very high0 Ų072 Ų720%034%0.339CS..G310 helixtrans-104.111.8179.500000113.6F518 H548 T550 E551 R552 F556 A613 V614 I650F518-A554 HydrophobicContact CD1-CB 3.61Å; F518-A554 HydrophobicContact CE1-CB 3.79Å; H548-A554 HydrophobicContact CB-CB 4.05Å; T550-A554 PolarHBondContact O-N 3.35Å; E551-A554 CarbonylContact O-C 3.48Å; E551-A554 WeakPolarHBondContact O-CA 3.47Å; E551-A554 PolarHBondContact O-N 3.11Å; R552-A554 PolarHBondContact O-N 3.1Å; A554-F556 WeakPolarHBondContact O-CD2 3.44Å; A554-F556 WeakPolarHBondContact O-CE2 3.24Å; A554-A613 WeakPolarHBondContact O-CA 3.47Å; A554-V614 HydrophobicContact CB-CB 3.73Å; A554-V614 HydrophobicContact CB-CG2 3.93Å; A554-V614 PolarHBondContact O-N 2.78Å; A554-I650 HydrophobicContact CB-CD1 3.6Å
555A98.4Very high96.5Very high18 Ų1871.7 Ų71.715%0.14933%0.334CS..  trans-99.491.6175.100000110.2E551 R552 Y610 A613 I644E551-A555 PolarHBondContact O-N 3.29Å; R552-A555 PolarHBondContact O-N 3.22Å; A555-Y610 HydrophobicContact CB-CD1 4.08Å; A555-Y610 HydrophobicContact CB-CE1 3.92Å; A555-A613 HydrophobicContact CB-CB 4.2Å; A555-I644 HydrophobicContact CB-CD1 4.08Å; A555-I644 HydrophobicContact CB-CG2 3.86Å
556F98.1Very high96.6Very high31 Ų3167.2 Ų67.214%0.13632%0.318CS..BIsolated β-bridgetrans-83.5129.8-178.2-56.3-83.3000109.8F518 T520 H548 A554 F562 P563 Y610 P611 L612F518-F556 AromaticContact CE1-CE2 3.72Å; F518-F556 HydrophobicContact CE1-CE2 3.72Å; F518-F556 AromaticContact CE1-CZ 3.93Å; F518-F556 HydrophobicContact CE1-CZ 3.93Å; F518-F556 AromaticContact CZ-CE2 3.83Å; F518-F556 HydrophobicContact CZ-CE2 3.83Å; F518-F556 HydrophobicContact CZ-CZ 4.2Å; T520-F556 HydrophobicContact CG2-CE1 4.29Å; T520-F556 HydrophobicContact CG2-CE2 4.46Å; T520-F556 HydrophobicContact CG2-CZ 3.65Å; H548-F556 AromaticContact CE1-CZ 3.8Å; H548-F556 AromaticContact NE2-CZ 3.89Å; A554-F556 WeakPolarHBondContact O-CD2 3.44Å; A554-F556 WeakPolarHBondContact O-CE2 3.24Å; F556-F562 HydrophobicContact CB-CD2 4.04Å; F556-F562 HydrophobicContact CB-CE2 3.95Å; F556-F562 HydrophobicContact CD2-CE2 4.36Å; F556-F562 HydrophobicContact CG-CD2 4.41Å; F556-F562 HydrophobicContact CG-CE2 4.19Å; F556-P563 HydrophobicContact CD1-CG 3.85Å; F556-P563 HydrophobicContact CE1-CG 3.39Å; F556-P563 HydrophobicContact CE2-CG 4.46Å; F556-P563 HydrophobicContact CZ-CG 3.75Å; F556-Y610 VanDerWaalsContact O-CA 3.23Å; F556-Y610 WeakPolarHBondContact O-CA 3.19Å; F556-Y610 WeakPolarHBondContact O-CB 3.29Å; F556-Y610 WeakPolarHBondContact O-CD1 3.41Å; F556-P611 HydrophobicContact CB-CG 4.41Å; F556-P611 WeakPolarHBondContact O-CD 3.44Å; F556-L612 HydrophobicContact CD2-CB 4.1Å; F556-L612 HydrophobicContact CD2-CD2 3.91Å; F556-L612 HydrophobicContact CD2-CG 4.41Å; F556-L612 HydrophobicContact CE2-CD2 3.97Å; F556-L612 PolarHBondContact N-O 3.36Å
557R96.6Very high96.6Very high112 Ų11264.7 Ų64.742%0.42330%0.302SS..PPolyproline II helixtrans-99.5149.7179.3-69.5-177178.4156.37.5112.1K560 R609 Y610R557-K560 PolarHBondContact O-N 2.86Å; R557-R609 VanDerWaalsContact CA-O 3.31Å; R557-R609 WeakPolarHBondContact CA-O 3.42Å; R557-Y610 HydrophobicContact CG-CD1 3.69Å; R557-Y610 HydrophobicContact CG-CE1 3.45Å; R557-Y610 VanDerWaalsContact CG-CE1 3.45Å; R557-Y610 PolarHBondContact NH2-OH 2.85Å
558F95.6Very high96.6Very high32 Ų3261 Ų6114%0.1428%0.284CS..THydrogen-bonded Turntrans-56.5153.1166.9-71.1-65.7000111.4K560 A591 S608 R609 P611 T660F558-K560 PolarHBondContact O-N 2.91Å; F558-A591 WeakPolarHBondContact CD1-O 3.16Å; F558-A591 HydrophobicContact CE1-CB 3.65Å; F558-A591 VanDerWaalsContact CE1-O 3.27Å; F558-A591 WeakPolarHBondContact CE1-O 3.45Å; F558-A591 HydrophobicContact CZ-CB 3.53Å; F558-S608 VanDerWaalsContact CD2-O 3.23Å; F558-S608 WeakPolarHBondContact CD2-O 3.46Å; F558-S608 VanDerWaalsContact CE2-O 3.23Å; F558-S608 WeakPolarHBondContact CE2-O 3.4Å; F558-R609 PolarHBondContact N-O 3.39Å; F558-R609 VanDerWaalsContact N-O 3.07Å; F558-P611 HydrophobicContact CD1-CB 4.26Å; F558-P611 HydrophobicContact CD1-CG 4.13Å; F558-P611 HydrophobicContact CE1-CB 3.67Å; F558-P611 HydrophobicContact CE1-CG 4.05Å; F558-P611 HydrophobicContact CZ-CB 3.84Å; F558-P611 HydrophobicContact CZ-CG 4.37Å; F558-T660 HydrophobicContact CE2-CG2 4.19Å; F558-T660 HydrophobicContact CZ-CG2 4.2Å
559G90.4Very high96.6Very high59 Ų5960.6 Ų60.661%0.60828%0.282SS*.THydrogen-bonded Turntrans74.71.1-175.100000115.2
560K93.4Very high96.6Very high164 Ų16455.2 Ų55.271%0.71326%0.259SS*.SBendtrans-109.6158.6170.7-59.8-60-177.5-172.20110.6R557 F558 F562R557-K560 PolarHBondContact O-N 2.86Å; F558-K560 PolarHBondContact O-N 2.91Å; K560-F562 PolarHBondContact O-N 3.36Å; K560-F562 VanDerWaalsContact O-N 3.08Å
561K92.2Very high96.5Very high159 Ų15955 Ų5569%0.69126%0.258SS*.  trans-60.2115.5175.5-176.6-176.3172.2-163.80109.1D522D522-K561 WeakPolarHBondContact OD2-CE 3.45Å; D522-K561 IonicContact OD2-NZ 2.73Å; D522-K561 PolarHBondContact OD2-NZ 2.57Å
562F94.3Very high96.5Very high64 Ų6459.2 Ų59.228%0.28129%0.288SS..  trans-80.7139.8175.5-165-104.8000110.8F556 K560 V566 F587 P611 L612F556-F562 HydrophobicContact CB-CD2 4.04Å; F556-F562 HydrophobicContact CB-CE2 3.95Å; F556-F562 HydrophobicContact CD2-CE2 4.36Å; F556-F562 HydrophobicContact CG-CD2 4.41Å; F556-F562 HydrophobicContact CG-CE2 4.19Å; K560-F562 PolarHBondContact O-N 3.36Å; K560-F562 VanDerWaalsContact O-N 3.08Å; F562-V566 HydrophobicContact CE1-CG2 3.85Å; F562-V566 HydrophobicContact CZ-CG2 3.78Å; F562-F587 AromaticContact CE1-CD2 3.49Å; F562-F587 HydrophobicContact CE1-CD2 3.49Å; F562-F587 VanDerWaalsContact CE1-CD2 3.49Å; F562-F587 AromaticContact CE1-CE2 3.64Å; F562-F587 HydrophobicContact CE1-CE2 3.64Å; F562-F587 HydrophobicContact CE1-CG 4.16Å; F562-F587 HydrophobicContact CE1-CZ 4.38Å; F562-F587 HydrophobicContact CE2-CE2 4.44Å; F562-F587 AromaticContact CZ-CD2 3.69Å; F562-F587 HydrophobicContact CZ-CD2 3.69Å; F562-F587 HydrophobicContact CZ-CE1 4.42Å; F562-F587 AromaticContact CZ-CE2 3.32Å; F562-F587 HydrophobicContact CZ-CE2 3.32Å; F562-F587 HydrophobicContact CZ-CG 4.43Å; F562-F587 AromaticContact CZ-CZ 3.74Å; F562-F587 HydrophobicContact CZ-CZ 3.74Å; F562-P611 HydrophobicContact CD2-CB 4.23Å; F562-P611 HydrophobicContact CD2-CG 3.79Å; F562-P611 HydrophobicContact CE2-CB 3.99Å; F562-P611 HydrophobicContact CE2-CG 3.84Å; F562-L612 HydrophobicContact CE2-CB 3.87Å; F562-L612 HydrophobicContact CZ-CB 4.01Å; F562-L612 HydrophobicContact CZ-CD2 4.46Å
563P93.3Very high96.5Very high18 Ų1856.2 Ų56.212%0.11728%0.28CS..  trans-63.3145.1178.3-19.330.7000112.9T520 F556 V566T520-P563 HydrophobicContact CG2-CB 3.58Å; T520-P563 HydrophobicContact CG2-CG 3.47Å; T520-P563 VanDerWaalsContact CG2-CG 3.47Å; F556-P563 HydrophobicContact CD1-CG 3.85Å; F556-P563 HydrophobicContact CE1-CG 3.39Å; F556-P563 HydrophobicContact CE2-CG 4.46Å; F556-P563 HydrophobicContact CZ-CG 3.75Å; P563-V566 HydrophobicContact CB-CG2 4.24Å; P563-V566 HydrophobicContact CG-CG2 4.5Å
564R93.7Very high96.5Very high161 Ų16160 Ų6061%0.60829%0.29SS*.SBendtrans-71.4-34.1177.6-65.8-175.7-178.8-172.20.6112.8D522D522-R564 WeakPolarHBondContact OD1-CD 3.47Å; D522-R564 IonicContact OD1-NE 3.61Å
565Y97.4Very high96.4Very high84 Ų8460.3 Ų60.333%0.32929%0.292SS..EExtended strand (participates in β ladder)trans-127.7122.9177.1-77.3-119000108.4T520 I521 R584 F689T520-Y565 VanDerWaalsContact CA-O 3.25Å; T520-Y565 WeakPolarHBondContact CA-O 3.37Å; I521-Y565 HydrophobicContact CB-CG 4.26Å; I521-Y565 PolarHBondContact N-O 3.26Å; I521-Y565 WeakPolarHBondContact O-CB 3.38Å; I521-Y565 PolarHBondContact O-N 2.76Å; Y565-R584 PolarHBondContact OH-NH1 2.97Å; Y565-R584 VanDerWaalsContact OH-NH1 3.1Å; Y565-F689 HydrophobicContact CD1-CE2 4.36Å; Y565-F689 HydrophobicContact CE1-CD2 4.41Å; Y565-F689 AromaticContact CE1-CE2 3.94Å; Y565-F689 HydrophobicContact CE1-CE2 3.94Å; Y565-F689 HydrophobicContact CE1-CZ 4.47Å
566V98.3Very high96.4Very high1 Ų166.8 Ų66.81%0.00632%0.317CS..EExtended strand (participates in β ladder)trans-112.5108175.4167.30000105.8F518 F562 P563 F568 R584 I585 L612F518-V566 HydrophobicContact CE2-CB 4.31Å; F518-V566 HydrophobicContact CE2-CG1 3.46Å; F518-V566 VanDerWaalsContact CE2-CG1 3.46Å; F518-V566 HydrophobicContact CZ-CB 4.5Å; F518-V566 HydrophobicContact CZ-CG1 3.8Å; F562-V566 HydrophobicContact CE1-CG2 3.85Å; F562-V566 HydrophobicContact CZ-CG2 3.78Å; P563-V566 HydrophobicContact CB-CG2 4.24Å; P563-V566 HydrophobicContact CG-CG2 4.5Å; V566-F568 HydrophobicContact CG1-CE2 4.17Å; V566-R584 CarbonylContact O-C 3.56Å; V566-R584 WeakPolarHBondContact O-CA 3.09Å; V566-R584 VanDerWaalsContact O-CB 3.29Å; V566-R584 WeakPolarHBondContact O-CB 3.49Å; V566-I585 HydrophobicContact CG1-CB 4.06Å; V566-I585 HydrophobicContact CG1-CG1 4.45Å; V566-I585 PolarHBondContact O-N 3.22Å; V566-L612 HydrophobicContact CB-CD2 4.3Å; V566-L612 HydrophobicContact CG1-CD2 3.23Å; V566-L612 HydrophobicContact CG2-CD2 4.07Å
567H98.6Very high96.5Very high3 Ų372.7 Ų72.71%0.01434%0.338CS..EExtended strand (participates in β ladder)trans-127.2123.3-164-179.6-130.9000112.1F518 E519 G582 Y583 F689F518-H567 VanDerWaalsContact CD2-O 3.29Å; F518-H567 WeakPolarHBondContact CD2-O 3.33Å; E519-H567 HydrophobicContact CG-CB 3.98Å; E519-H567 PolarHBondContact N-O 2.9Å; E519-H567 PolarHBondContact O-N 2.86Å; E519-H567 IonicContact OE1-CE1 3.96Å; E519-H567 IonicContact OE1-CG 3.69Å; E519-H567 IonicContact OE1-ND1 3.79Å; E519-H567 PolarHBondContact OE1-ND1 2.92Å; H567-G582 WeakPolarHBondContact NE2-CA 3.19Å; H567-Y583 PolarHBondContact CD2-O 3.34Å; H567-F689 AromaticContact CD2-CD1 3.78Å; H567-F689 AromaticContact CE1-CD1 3.69Å; H567-F689 AromaticContact NE2-CD1 3.45Å; H567-F689 WeakPolarHBondContact NE2-CD1 3.47Å
568F98.8Very high96.5Very high0 Ų069.4 Ų69.40%034%0.339CS..EExtended strand (participates in β ladder)trans-102.3133171.8-68.6-101.9000108.7L509 I511 S517 F518 V566 G582 Y583 I585 V614 L655 A657L509-F568 HydrophobicContact CD1-CB 3.86Å; L509-F568 HydrophobicContact CD1-CD1 4.04Å; L509-F568 HydrophobicContact CD1-CD2 3.57Å; L509-F568 HydrophobicContact CD1-CE1 4.49Å; L509-F568 HydrophobicContact CD1-CE2 4.09Å; L509-F568 HydrophobicContact CD1-CG 3.55Å; I511-F568 HydrophobicContact CG1-CB 4.39Å; S517-F568 WeakPolarHBondContact O-CA 3.49Å; F518-F568 HydrophobicContact CB-CE1 4.46Å; F518-F568 HydrophobicContact CD2-CD1 4.21Å; F518-F568 AromaticContact CD2-CD2 3.93Å; F518-F568 HydrophobicContact CD2-CD2 3.93Å; F518-F568 HydrophobicContact CD2-CE1 4.01Å; F518-F568 AromaticContact CD2-CE2 3.7Å; F518-F568 HydrophobicContact CD2-CE2 3.7Å; F518-F568 HydrophobicContact CD2-CG 4.17Å; F518-F568 AromaticContact CD2-CZ 3.74Å; F518-F568 HydrophobicContact CD2-CZ 3.74Å; F518-F568 HydrophobicContact CE2-CD2 4.25Å; F518-F568 AromaticContact CE2-CE2 3.81Å; F518-F568 HydrophobicContact CE2-CE2 3.81Å; F518-F568 HydrophobicContact CE2-CZ 4.13Å; F518-F568 HydrophobicContact CG-CE1 4.47Å; F518-F568 HydrophobicContact CG-CZ 4.46Å; V566-F568 HydrophobicContact CG1-CE2 4.17Å; F568-G582 CarbonylContact O-C 3.52Å; F568-G582 WeakPolarHBondContact O-CA 3.2Å; F568-Y583 PolarHBondContact N-O 3.15Å; F568-Y583 PolarHBondContact O-N 3.11Å; F568-I585 HydrophobicContact CD2-CD1 4.3Å; F568-I585 HydrophobicContact CD2-CG1 4.29Å; F568-I585 HydrophobicContact CE2-CD1 3.66Å; F568-I585 HydrophobicContact CE2-CG1 4.06Å; F568-I585 HydrophobicContact CZ-CD1 4.42Å; F568-V614 HydrophobicContact CE1-CG1 3.7Å; F568-V614 HydrophobicContact CE1-CG2 4.09Å; F568-V614 HydrophobicContact CZ-CB 4.47Å; F568-V614 HydrophobicContact CZ-CG1 4.07Å; F568-V614 HydrophobicContact CZ-CG2 3.58Å; F568-L655 HydrophobicContact CD1-CB 4.41Å; F568-L655 HydrophobicContact CD1-CD1 4.19Å; F568-L655 HydrophobicContact CE1-CB 4.25Å; F568-L655 HydrophobicContact CE1-CD1 4.28Å; F568-A657 HydrophobicContact CE1-CB 4.2Å; F568-A657 HydrophobicContact CE2-CB 3.97Å; F568-A657 HydrophobicContact CZ-CB 3.44Å; F568-A657 VanDerWaalsContact CZ-CB 3.44Å
569Y98.8Very high96.7Very high12 Ų1272.2 Ų72.25%0.04735%0.353CS..EExtended strand (participates in β ladder)trans-145.2154-176.868.2-83.9000112.2N516 S517 E519 E547 P571 Q580 K581N516-Y569 CarbonylContact C-O 3.08Å; N516-Y569 WeakPolarHBondContact CA-O 3.35Å; S517-Y569 VanDerWaalsContact CB-CZ 3.49Å; S517-Y569 PolarHBondContact N-O 2.78Å; S517-Y569 WeakPolarHBondContact O-CD1 3.49Å; S517-Y569 PolarHBondContact O-N 2.67Å; E519-Y569 HydrophobicContact CB-CE1 3.99Å; E519-Y569 HydrophobicContact CG-CD1 4.06Å; E519-Y569 HydrophobicContact CG-CE1 3.86Å; E547-Y569 PolarHBondContact OE1-OH 3.45Å; Y569-P571 HydrophobicContact CE2-CB 4.13Å; Y569-Q580 HydrophobicContact CD2-CB 3.69Å; Y569-Q580 HydrophobicContact CD2-CG 3.87Å; Y569-Q580 HydrophobicContact CE2-CG 4.24Å; Y569-Q580 HydrophobicContact CG-CB 4.27Å; Y569-K581 VanDerWaalsContact CA-O 3.31Å; Y569-K581 WeakPolarHBondContact CA-O 3.23Å; Y569-K581 WeakPolarHBondContact CB-O 3.23Å
570N98.6Very high97.1Very high8 Ų872.2 Ų72.24%0.04334%0.337CS..EExtended strand (participates in β ladder)trans-92.7117.8171.5-173.4-40.4000109I511 V512 S572 E573 K581I511-N570 HydrophobicContact CG2-CB 4.47Å; I511-N570 WeakPolarHBondContact O-CB 3.19Å; I511-N570 PolarHBondContact O-ND2 2.86Å; V512-N570 PolarHBondContact O-ND2 2.94Å; V512-N570 VanDerWaalsContact O-ND2 3.16Å; N570-S572 VanDerWaalsContact C-N 3.25Å; N570-S572 PolarHBondContact O-N 3.46Å; N570-S572 WeakPolarHBondContact OD1-CB 3.48Å; N570-S572 PolarHBondContact OD1-N 2.86Å; N570-E573 HydrophobicContact CB-CB 4.09Å; N570-E573 HydrophobicContact CB-CG 4.44Å; N570-E573 PolarHBondContact OD1-N 2.93Å; N570-K581 PolarHBondContact N-O 3.29Å
571P97.1Very high97.3Very high38 Ų3865.7 Ų65.725%0.24731%0.309CS..EExtended strand (participates in β ladder)trans-71-21.7-176.429-34.2000113.2D515 Y569 N652D515-P571 WeakPolarHBondContact O-CD 3.43Å; Y569-P571 HydrophobicContact CE2-CB 4.13Å; P571-N652 HydrophobicContact CG-CB 4.18Å; P571-N652 WeakPolarHBondContact CG-OD1 3.48Å
572S97.6Very high97.6Very high89 Ų8958.1 Ų58.162%0.62228%0.276SS*.EExtended strand (participates in β ladder)trans-87.8-21.8-177.9-56.30000112.7N570N570-S572 VanDerWaalsContact C-N 3.25Å; N570-S572 PolarHBondContact O-N 3.46Å; N570-S572 WeakPolarHBondContact OD1-CB 3.48Å; N570-S572 PolarHBondContact OD1-N 2.86Å
573E97.9Very high97.8Very high79 Ų7955 Ų5537%0.36926%0.262SS..EExtended strand (participates in β ladder)trans-108.3123.5-173.9-66.6-62.3145.600111.4V512 N570 Q580 K581V512-E573 HydrophobicContact CB-CG 4.17Å; V512-E573 HydrophobicContact CG1-CG 3.93Å; N570-E573 HydrophobicContact CB-CB 4.09Å; N570-E573 HydrophobicContact CB-CG 4.44Å; N570-E573 PolarHBondContact OD1-N 2.93Å; E573-Q580 WeakPolarHBondContact O-CA 3.33Å; E573-K581 HydrophobicContact CB-CB 4.41Å; E573-K581 HydrophobicContact CB-CD 4.26Å; E573-K581 HydrophobicContact CB-CG 4.41Å; E573-K581 PolarHBondContact O-N 3.19Å
574K98.3Very high98Very high127 Ų12755.9 Ų55.955%0.55226%0.263SS*.EExtended strand (participates in β ladder)trans-119.5146.5-179.6-66.9178179.2-179.50111.2H579K574-H579 CarbonylContact C-O 3.17Å; K574-H579 VanDerWaalsContact CA-O 3.23Å; K574-H579 WeakPolarHBondContact CA-O 3.31Å
575N98.2Very high98.3Very high8 Ų848.4 Ų48.44%0.04324%0.235CC..  trans-73.7174.2165.674.27.2000111W577 G578 H579 N690N575-W577 PolarHBondContact O-N 2.66Å; N575-W577 WeakPolarHBondContact OD1-CA 3.5Å; N575-W577 WeakPolarHBondContact OD1-CB 3.11Å; N575-W577 PolarHBondContact OD1-N 3.46Å; N575-G578 PolarHBondContact O-N 2.72Å; N575-G578 PolarHBondContact OD1-N 2.8Å; N575-H579 PolarHBondContact N-O 3.34Å; N575-H579 PolarHBondContact OD1-N 3.02Å; N575-H579 VanDerWaalsContact OD1-N 3.09Å; N575-H579 PolarHBondContact OD1-O 3Å; N575-N690 WeakPolarHBondContact CB-O 3.49Å; N575-N690 PolarHBondContact ND2-O 3.02Å; N575-N690 VanDerWaalsContact ND2-O 3.12Å
576K98.4Very high98.3Very high154 Ų15447.7 Ų47.767%0.6724%0.235SC*.THydrogen-bonded Turntrans-55.4-22.3179.1-177.7178.5175.6-176.50113.7N693K576-N693 HydrophobicContact CB-CB 4.32Å; K576-N693 VanDerWaalsContact CB-OD1 3.29Å; K576-N693 WeakPolarHBondContact CB-OD1 3.39Å; K576-N693 PolarHBondContact N-OD1 3.09Å
577W98.4Very high98.2Very high154 Ų15449.8 Ų49.858%0.58324%0.244SC*.THydrogen-bonded Turntrans-94.13.6-178.3-43.8121.1000113.3N575 H579 N693N575-W577 PolarHBondContact O-N 2.66Å; N575-W577 WeakPolarHBondContact OD1-CA 3.5Å; N575-W577 WeakPolarHBondContact OD1-CB 3.11Å; N575-W577 PolarHBondContact OD1-N 3.46Å; W577-H579 VanDerWaalsContact C-N 3.31Å; W577-H579 PolarHBondContact O-N 2.78Å; W577-N693 PolarHBondContact NE1-O 3Å
578G98.2Very high98Very high43 Ų4352.5 Ų52.544%0.44326%0.258SS..SBendtrans81.55.6178.100000114.8N575N575-G578 PolarHBondContact O-N 2.72Å; N575-G578 PolarHBondContact OD1-N 2.8Å
579H98.4Very high98Very high91 Ų9154.2 Ų54.242%0.42127%0.27SS..PPolyproline II helixtrans-84.9143.5173.1-64.5-63000110.5K574 N575 W577 N690K574-H579 CarbonylContact C-O 3.17Å; K574-H579 VanDerWaalsContact CA-O 3.23Å; K574-H579 WeakPolarHBondContact CA-O 3.31Å; N575-H579 PolarHBondContact N-O 3.34Å; N575-H579 PolarHBondContact OD1-N 3.02Å; N575-H579 VanDerWaalsContact OD1-N 3.09Å; N575-H579 PolarHBondContact OD1-O 3Å; W577-H579 VanDerWaalsContact C-N 3.31Å; W577-H579 PolarHBondContact O-N 2.78Å; H579-N690 HydrophobicContact CB-CB 3.73Å
580Q98.4Very high97.8Very high60 Ų6059.9 Ų59.928%0.2830%0.297SS..EExtended strand (participates in β ladder)trans-62.6137.5175.8-67.1138.2-2400110.3Y569 E573Y569-Q580 HydrophobicContact CD2-CB 3.69Å; Y569-Q580 HydrophobicContact CD2-CG 3.87Å; Y569-Q580 HydrophobicContact CE2-CG 4.24Å; Y569-Q580 HydrophobicContact CG-CB 4.27Å; E573-Q580 WeakPolarHBondContact O-CA 3.33Å
581K98.7Very high97.7Very high26 Ų2660.1 Ų60.111%0.11330%0.301CS..EExtended strand (participates in β ladder)trans-68.7130.8174.3-70.7-168.9168.7-176.10109.3E333 V512 Y569 N570 E573 F691E333-K581 IonicContact OE1-NZ 3.79Å; E333-K581 PolarHBondContact OE1-NZ 3.01Å; E333-K581 IonicContact OE2-NZ 3.85Å; E333-K581 PolarHBondContact OE2-NZ 3.38Å; V512-K581 HydrophobicContact CG2-CD 3.8Å; Y569-K581 VanDerWaalsContact CA-O 3.31Å; Y569-K581 WeakPolarHBondContact CA-O 3.23Å; Y569-K581 WeakPolarHBondContact CB-O 3.23Å; N570-K581 PolarHBondContact N-O 3.29Å; E573-K581 HydrophobicContact CB-CB 4.41Å; E573-K581 HydrophobicContact CB-CD 4.26Å; E573-K581 HydrophobicContact CB-CG 4.41Å; E573-K581 PolarHBondContact O-N 3.19Å; K581-F691 HydrophobicContact CB-CD2 4.11Å; K581-F691 WeakPolarHBondContact CD-O 3.23Å; K581-F691 VanDerWaalsContact CE-O 3.32Å; K581-F691 WeakPolarHBondContact CE-O 3.37Å; K581-F691 WeakPolarHBondContact CG-O 3.21Å
582G98.5Very high97.6Very high0 Ų063.5 Ų63.50%031%0.313CS..EExtended strand (participates in β ladder)trans-159.4165.6-177.100000115.4H567 F568 F689 F691H567-G582 WeakPolarHBondContact NE2-CA 3.19Å; F568-G582 CarbonylContact O-C 3.52Å; F568-G582 WeakPolarHBondContact O-CA 3.2Å; G582-F689 CarbonylContact C-O 3.53Å; G582-F689 PolarHBondContact N-O 3.48Å; G582-F689 CarbonylContact O-C 3.55Å; G582-F689 PolarHBondContact O-N 3.25Å; G582-F691 WeakPolarHBondContact O-CB 3.37Å
583Y98.8Very high97.3Very high0 Ų061.7 Ų61.70%030%0.3CS..EExtended strand (participates in β ladder)trans-124141.7173.2-93.7-107.2000109.4I335 G462 I511 H567 F568 L686 R687 P688 F691I335-Y583 HydrophobicContact CB-CE2 4.45Å; I335-Y583 HydrophobicContact CD1-CE1 4.26Å; I335-Y583 HydrophobicContact CD1-CE2 4.08Å; I335-Y583 WeakPolarHBondContact CD1-OH 3.5Å; I335-Y583 HydrophobicContact CG1-CE2 3.78Å; I335-Y583 HydrophobicContact CG2-CD1 3.9Å; I335-Y583 HydrophobicContact CG2-CD2 3.94Å; I335-Y583 HydrophobicContact CG2-CE1 3.83Å; I335-Y583 HydrophobicContact CG2-CE2 3.86Å; I335-Y583 HydrophobicContact CG2-CG 3.96Å; G462-Y583 WeakPolarHBondContact O-CE1 3.47Å; G462-Y583 PolarHBondContact O-OH 3.07Å; I511-Y583 HydrophobicContact CD1-CD2 3.9Å; I511-Y583 HydrophobicContact CD1-CG 4.08Å; H567-Y583 PolarHBondContact CD2-O 3.34Å; F568-Y583 PolarHBondContact N-O 3.15Å; F568-Y583 PolarHBondContact O-N 3.11Å; Y583-L686 HydrophobicContact CD1-CB 4.08Å; Y583-R687 CarbonylContact C-O 3.48Å; Y583-R687 WeakPolarHBondContact CA-O 3.2Å; Y583-P688 HydrophobicContact CE1-CB 4.15Å; Y583-P688 HydrophobicContact CE1-CG 4.49Å; Y583-P688 HydrophobicContact CE2-CB 3.98Å; Y583-F691 HydrophobicContact CD2-CB 4.29Å; Y583-F691 AromaticContact CD2-CD2 3.66Å; Y583-F691 HydrophobicContact CD2-CD2 3.66Å; Y583-F691 HydrophobicContact CD2-CE2 4.18Å; Y583-F691 HydrophobicContact CD2-CG 4.06Å; Y583-F691 HydrophobicContact CE2-CB 4Å; Y583-F691 HydrophobicContact CE2-CD1 4.03Å; Y583-F691 AromaticContact CE2-CD2 3.51Å; Y583-F691 HydrophobicContact CE2-CD2 3.51Å; Y583-F691 HydrophobicContact CE2-CE1 4.38Å; Y583-F691 AromaticContact CE2-CE2 3.89Å; Y583-F691 HydrophobicContact CE2-CE2 3.89Å; Y583-F691 AromaticContact CE2-CG 3.57Å; Y583-F691 HydrophobicContact CE2-CG 3.57Å; Y583-F691 HydrophobicContact CE2-CZ 4.32Å
584R98.1Very high97Very high35 Ų3559.7 Ų59.713%0.13229%0.293CS..EExtended strand (participates in β ladder)trans-106.4142.6173.875.8177-157.6-16710.3111.3Y565 V566 L686 R687Y565-R584 PolarHBondContact OH-NH1 2.97Å; Y565-R584 VanDerWaalsContact OH-NH1 3.1Å; V566-R584 CarbonylContact O-C 3.56Å; V566-R584 WeakPolarHBondContact O-CA 3.09Å; V566-R584 VanDerWaalsContact O-CB 3.29Å; V566-R584 WeakPolarHBondContact O-CB 3.49Å; R584-L686 WeakPolarHBondContact O-CA 3.04Å; R584-R687 HydrophobicContact CG-CB 3.89Å; R584-R687 PolarHBondContact N-O 3.25Å; R584-R687 PolarHBondContact O-N 2.65Å
585I98.8Very high96.7Very high5 Ų555 Ų553%0.02627%0.274CS..EExtended strand (participates in β ladder)trans-90.8124.4168.5-52.3-171.4000107.8L509 V566 F568 F587 L612 A657 V659 F684 F685 L686L509-I585 HydrophobicContact CD1-CD1 4.41Å; V566-I585 HydrophobicContact CG1-CB 4.06Å; V566-I585 HydrophobicContact CG1-CG1 4.45Å; V566-I585 PolarHBondContact O-N 3.22Å; F568-I585 HydrophobicContact CD2-CD1 4.3Å; F568-I585 HydrophobicContact CD2-CG1 4.29Å; F568-I585 HydrophobicContact CE2-CD1 3.66Å; F568-I585 HydrophobicContact CE2-CG1 4.06Å; F568-I585 HydrophobicContact CZ-CD1 4.42Å; I585-F587 HydrophobicContact CG2-CD2 4.23Å; I585-F587 HydrophobicContact CG2-CE2 3.74Å; I585-F587 HydrophobicContact CG2-CZ 4.35Å; I585-L612 HydrophobicContact CD1-CD1 4.15Å; I585-A657 HydrophobicContact CD1-CB 3.6Å; I585-V659 HydrophobicContact CD1-CG2 4.16Å; I585-V659 HydrophobicContact CG2-CG2 4.34Å; I585-F684 HydrophobicContact CG2-CB 4.2Å; I585-F684 HydrophobicContact CG2-CD2 4.08Å; I585-F684 HydrophobicContact CG2-CG 4.37Å; I585-F685 CarbonylContact C-O 3.45Å; I585-F685 WeakPolarHBondContact CA-O 3.25Å; I585-L686 HydrophobicContact CB-CD2 4.46Å; I585-L686 HydrophobicContact CD1-CD2 4.26Å; I585-L686 HydrophobicContact CG1-CD2 3.7Å
586Q98.4Very high96.6Very high68 Ų6858.8 Ų58.832%0.31830%0.299SS..EExtended strand (participates in β ladder)trans-119.6121.1176178.3-176.4-30.700109.7F684 F685 R687Q586-F684 CarbonylContact O-C 3.59Å; Q586-F684 WeakPolarHBondContact O-CA 3.37Å; Q586-F684 WeakPolarHBondContact O-CB 3.44Å; Q586-F685 HydrophobicContact CB-CB 4.31Å; Q586-F685 PolarHBondContact N-O 3.2Å; Q586-F685 PolarHBondContact O-N 3.37Å; Q586-R687 VanDerWaalsContact OE1-CD 3.26Å
587F94.6Very high96.3Very high46 Ų4657.3 Ų57.320%0.20229%0.293CS..EExtended strand (participates in β ladder)trans-80.5146-174.4-75.5-107.3000112.6F562 I585 P611 L612 V659 V661F562-F587 AromaticContact CE1-CD2 3.49Å; F562-F587 HydrophobicContact CE1-CD2 3.49Å; F562-F587 VanDerWaalsContact CE1-CD2 3.49Å; F562-F587 AromaticContact CE1-CE2 3.64Å; F562-F587 HydrophobicContact CE1-CE2 3.64Å; F562-F587 HydrophobicContact CE1-CG 4.16Å; F562-F587 HydrophobicContact CE1-CZ 4.38Å; F562-F587 HydrophobicContact CE2-CE2 4.44Å; F562-F587 AromaticContact CZ-CD2 3.69Å; F562-F587 HydrophobicContact CZ-CD2 3.69Å; F562-F587 HydrophobicContact CZ-CE1 4.42Å; F562-F587 AromaticContact CZ-CE2 3.32Å; F562-F587 HydrophobicContact CZ-CE2 3.32Å; F562-F587 HydrophobicContact CZ-CG 4.43Å; F562-F587 AromaticContact CZ-CZ 3.74Å; F562-F587 HydrophobicContact CZ-CZ 3.74Å; I585-F587 HydrophobicContact CG2-CD2 4.23Å; I585-F587 HydrophobicContact CG2-CE2 3.74Å; I585-F587 HydrophobicContact CG2-CZ 4.35Å; F587-P611 HydrophobicContact CE1-CB 4.23Å; F587-P611 WeakPolarHBondContact CE1-O 3.28Å; F587-P611 VanDerWaalsContact CZ-O 3.3Å; F587-P611 WeakPolarHBondContact CZ-O 3.47Å; F587-L612 HydrophobicContact CE2-CB 4.45Å; F587-L612 HydrophobicContact CE2-CD1 4.4Å; F587-L612 HydrophobicContact CZ-CB 3.87Å; F587-L612 HydrophobicContact CZ-CD1 4Å; F587-L612 HydrophobicContact CZ-CG 4.47Å; F587-V659 HydrophobicContact CD1-CG1 4.41Å; F587-V659 HydrophobicContact CE1-CG1 3.58Å; F587-V659 HydrophobicContact CZ-CG1 3.77Å; F587-V659 HydrophobicContact CZ-CG2 4.48Å; F587-V661 HydrophobicContact CD1-CG1 4.36Å
588N96.1Very high95.9Very high59 Ų5952.4 Ų52.432%0.31629%0.289SS..EExtended strand (participates in β ladder)trans-127.987.3160.6178.231.9000107.9A681 V682 G683N588-A681 PolarHBondContact ND2-O 3.3Å; N588-V682 CarbonylContact O-C 3.54Å; N588-V682 VanDerWaalsContact O-CA 3.3Å; N588-V682 WeakPolarHBondContact O-CA 3.12Å; N588-V682 WeakPolarHBondContact O-CB 3.3Å; N588-G683 CarbonylContact C-O 3.49Å; N588-G683 WeakPolarHBondContact CA-O 3.06Å; N588-G683 PolarHBondContact N-O 2.89Å; N588-G683 PolarHBondContact O-N 3.11Å; N588-G683 VanDerWaalsContact O-O 3.05Å
589S96.9Very high95.7Very high36 Ų3656.5 Ų56.525%0.25229%0.292SS..  trans-153.9150.2-175.3177.30000111.9A591 V661 G662S589-A591 WeakPolarHBondContact OG-CB 3.19Å; S589-A591 PolarHBondContact OG-N 3.15Å; S589-V661 WeakPolarHBondContact OG-CA 3.45Å; S589-G662 PolarHBondContact OG-N 2.83Å; S589-G662 VanDerWaalsContact OG-N 3.07Å; S589-G662 PolarHBondContact OG-O 3.32Å
590H96.2Very high95.5Very high131 Ų13158.2 Ų58.261%0.60629%0.294SS*.  trans-115.823.7172.1-53.398.5000111.1G662 F663H590-G662 CarbonylContact C-O 3.57Å; H590-G662 VanDerWaalsContact C-O 3.29Å; H590-G662 PolarHBondContact N-O 2.85Å; H590-F663 HydrophobicContact CB-CB 4.07Å
591A95.1Very high95.4Very high14 Ų1455.7 Ų55.712%0.11628%0.283CS..  trans-70.8151.9-174.700000112L502 F558 S589 G662L502-A591 HydrophobicContact CD2-CB 3.51Å; F558-A591 WeakPolarHBondContact CD1-O 3.16Å; F558-A591 HydrophobicContact CE1-CB 3.65Å; F558-A591 VanDerWaalsContact CE1-O 3.27Å; F558-A591 WeakPolarHBondContact CE1-O 3.45Å; F558-A591 HydrophobicContact CZ-CB 3.53Å; S589-A591 WeakPolarHBondContact OG-CB 3.19Å; S589-A591 PolarHBondContact OG-N 3.15Å; A591-G662 PolarHBondContact N-O 2.97Å
592H95.1Very high95.3Very high109 Ų10954.5 Ų54.551%0.50528%0.277SS..  trans-142.9167.1169-159.4-83.5000109.6V594H592-V594 PolarHBondContact O-N 3.15Å
593S91.3Very high95.1Very high50 Ų5056.7 Ų56.735%0.3529%0.291SS..  trans-56.6132171.2-166.30000110.2L595S593-L595 PolarHBondContact OG-O 2.89Å
594V91.4Very high95Very high37 Ų3756.7 Ų56.722%0.22429%0.291CS..  trans-97.2-42.9-17665.80000113.4I345 F347 L502 H592 I605I345-V594 HydrophobicContact CD1-CG1 4.24Å; F347-V594 HydrophobicContact CB-CG2 3.59Å; F347-V594 HydrophobicContact CD2-CG1 3.97Å; F347-V594 HydrophobicContact CD2-CG2 3.96Å; F347-V594 HydrophobicContact CE2-CG1 4.4Å; F347-V594 HydrophobicContact CG-CG1 4.5Å; F347-V594 HydrophobicContact CG-CG2 4.11Å; L502-V594 HydrophobicContact CD1-CB 4.24Å; L502-V594 HydrophobicContact CD1-CG1 3.97Å; H592-V594 PolarHBondContact O-N 3.15Å; V594-I605 HydrophobicContact CG1-CD1 3.87Å
595L93.6Very high95Very high28 Ų2855 Ų5515%0.14729%0.285CS..SBendtrans-115.9154.8175.7-70.5-176.2000111.4F347 S593 E601 E602F347-L595 HydrophobicContact CD2-CD1 4.05Å; F347-L595 HydrophobicContact CD2-CG 3.99Å; F347-L595 HydrophobicContact CE2-CD1 3.57Å; F347-L595 HydrophobicContact CE2-CG 3.98Å; S593-L595 PolarHBondContact OG-O 2.89Å; L595-E601 HydrophobicContact CD1-CB 4.35Å; L595-E602 HydrophobicContact CB-CB 3.75Å; L595-E602 HydrophobicContact CB-CG 3.69Å; L595-E602 HydrophobicContact CD1-CB 3.9Å
596P94.5Very high94.9Very high88 Ų8854.8 Ų54.857%0.57128%0.284SS*.  trans-62142.2171.1-2032.2000111.6G598 W599P596-G598 PolarHBondContact O-N 3.07Å; P596-W599 HydrophobicContact CB-CB 4.16Å; P596-W599 HydrophobicContact CG-CB 4.47Å; P596-W599 VanDerWaalsContact O-CB 3.25Å; P596-W599 WeakPolarHBondContact O-CB 3.27Å; P596-W599 PolarHBondContact O-N 3.29Å; P596-W599 VanDerWaalsContact O-N 3.11Å
597K93.3Very high94.9Very high124 Ų12451.6 Ų51.654%0.53927%0.268SS..THydrogen-bonded Turntrans-57.6126.1179.5-180179-179.7178.80111.6W599K597-W599 PolarHBondContact O-N 3.15Å
598G90.5Very high95Very high50 Ų5049.4 Ų49.452%0.51526%0.259SS..THydrogen-bonded Turntrans794.7176.400000113.9P596 R600 E602P596-G598 PolarHBondContact O-N 3.07Å; G598-R600 PolarHBondContact O-N 2.99Å; G598-E602 PolarHBondContact N-OE2 3.05Å
599W94Very high95.1Very high130 Ų13047.7 Ų47.749%0.49225%0.248SC..  trans-75110.1174.6178-97.1000110.3P596 K597 E601 E602P596-W599 HydrophobicContact CB-CB 4.16Å; P596-W599 HydrophobicContact CG-CB 4.47Å; P596-W599 VanDerWaalsContact O-CB 3.25Å; P596-W599 WeakPolarHBondContact O-CB 3.27Å; P596-W599 PolarHBondContact O-N 3.29Å; P596-W599 VanDerWaalsContact O-N 3.11Å; K597-W599 PolarHBondContact O-N 3.15Å; W599-E601 PolarHBondContact NE1-OE2 3.4Å; W599-E601 PolarHBondContact O-N 2.82Å; W599-E602 WeakPolarHBondContact O-CA 3.4Å; W599-E602 WeakPolarHBondContact O-CB 3.33Å; W599-E602 PolarHBondContact O-N 3.19Å
600R93.9Very high95.1Very high126 Ų12646.1 Ų46.148%0.47524%0.236SC..G310 helixtrans36.2-102165.2-62.9-172.7-177.6-1551.2114.1G598 E602 V603G598-R600 PolarHBondContact O-N 2.99Å; R600-E602 VanDerWaalsContact C-N 3.25Å; R600-E602 PolarHBondContact O-N 2.79Å; R600-V603 WeakPolarHBondContact O-CG2 3.32Å; R600-V603 PolarHBondContact O-N 2.78Å
601E95.4Very high95.2Very high8 Ų840.3 Ų40.34%0.03721%0.211CC..G310 helixtrans-67.5-21.7-174.8-53.672.9-153.900113.4P188 K359 L595 W599 V603 G604 P633 W634P188-E601 HydrophobicContact CG-CG 4.2Å; K359-E601 HydrophobicContact CD-CB 4.25Å; K359-E601 HydrophobicContact CD-CG 4.01Å; L595-E601 HydrophobicContact CD1-CB 4.35Å; W599-E601 PolarHBondContact NE1-OE2 3.4Å; W599-E601 PolarHBondContact O-N 2.82Å; E601-V603 PolarHBondContact O-N 3.07Å; E601-V603 VanDerWaalsContact O-N 3.15Å; E601-G604 PolarHBondContact O-N 2.79Å; E601-G604 VanDerWaalsContact O-N 3.13Å; E601-P633 HydrophobicContact CB-CB 4.12Å; E601-P633 HydrophobicContact CB-CG 3.97Å; E601-P633 HydrophobicContact CG-CG 3.97Å; E601-W634 HydrophobicContact CG-CZ2 4.23Å; E601-W634 PolarHBondContact OE1-NE1 3.07Å
602E96.6Very high95.4Very high0 Ų039.7 Ų39.70%021%0.205CC..G310 helixtrans-61.7-23.1179.1-167.4-85.5157.700112.4L595 G598 W599 R600 G604 I605 S606 R609L595-E602 HydrophobicContact CB-CB 3.75Å; L595-E602 HydrophobicContact CB-CG 3.69Å; L595-E602 HydrophobicContact CD1-CB 3.9Å; G598-E602 PolarHBondContact N-OE2 3.05Å; W599-E602 WeakPolarHBondContact O-CA 3.4Å; W599-E602 WeakPolarHBondContact O-CB 3.33Å; W599-E602 PolarHBondContact O-N 3.19Å; R600-E602 VanDerWaalsContact C-N 3.25Å; R600-E602 PolarHBondContact O-N 2.79Å; E602-G604 VanDerWaalsContact C-N 3.27Å; E602-G604 PolarHBondContact O-N 3.22Å; E602-I605 CarbonylContact O-C 3.51Å; E602-I605 PolarHBondContact O-N 2.92Å; E602-I605 VanDerWaalsContact O-N 3.1Å; E602-S606 PolarHBondContact O-N 2.98Å; E602-S606 VanDerWaalsContact O-N 3.15Å; E602-R609 WeakPolarHBondContact OE1-CG 3.26Å; E602-R609 IonicContact OE1-CZ 2.58Å; E602-R609 IonicContact OE1-NE 3.16Å; E602-R609 PolarHBondContact OE1-NE 2.75Å; E602-R609 IonicContact OE1-NH2 2.88Å; E602-R609 PolarHBondContact OE1-NH2 2.98Å; E602-R609 IonicContact OE2-CZ 3.4Å; E602-R609 IonicContact OE2-NE 2.66Å; E602-R609 PolarHBondContact OE2-NE 2.61Å; E602-R609 IonicContact OE2-NH2 2.79Å; E602-R609 PolarHBondContact OE2-NH2 3.14Å
603V95.3Very high95.6Very high46 Ų4634.5 Ų34.528%0.27918%0.182SC..G310 helixtrans-58.6-40.8175.6-179.40000111.1R600 E601 I605 P636R600-V603 WeakPolarHBondContact O-CG2 3.32Å; R600-V603 PolarHBondContact O-N 2.78Å; E601-V603 PolarHBondContact O-N 3.07Å; E601-V603 VanDerWaalsContact O-N 3.15Å; V603-I605 VanDerWaalsContact C-N 3.25Å; V603-I605 PolarHBondContact O-N 3.02Å; V603-P636 HydrophobicContact CG1-CG 4.04Å
604G96.2Very high95.9Very high1 Ų132.1 Ų32.11%0.0117%0.165CC..G310 helixtrans-65.9-22.5176.500000114.6E601 E602 T629 P633E601-G604 PolarHBondContact O-N 2.79Å; E601-G604 VanDerWaalsContact O-N 3.13Å; E602-G604 VanDerWaalsContact C-N 3.27Å; E602-G604 PolarHBondContact O-N 3.22Å; G604-T629 WeakPolarHBondContact O-CG2 3.49Å; G604-P633 WeakPolarHBondContact CA-O 3.32Å; G604-P633 PolarHBondContact N-O 3.29Å
605I97.3Very high96.3Very high0 Ų030.4 Ų30.40%016%0.155CC..G310 helixtrans-122.434.5-178.260.3154.2000112.2I345 F347 I361 V594 E602 V603 W607 S608I345-I605 HydrophobicContact CD1-CD1 3.92Å; I345-I605 HydrophobicContact CG2-CG2 4.23Å; F347-I605 HydrophobicContact CD2-CD1 4.21Å; F347-I605 HydrophobicContact CE1-CD1 4.34Å; F347-I605 HydrophobicContact CE2-CD1 3.33Å; F347-I605 HydrophobicContact CE2-CG1 4.31Å; F347-I605 HydrophobicContact CZ-CD1 3.42Å; F347-I605 VanDerWaalsContact CZ-CD1 3.42Å; F347-I605 HydrophobicContact CZ-CG1 4.14Å; F347-I605 HydrophobicContact CZ-CG2 4.14Å; I361-I605 HydrophobicContact CD1-CG2 3.76Å; I361-I605 HydrophobicContact CG1-CG2 4.18Å; V594-I605 HydrophobicContact CG1-CD1 3.87Å; E602-I605 CarbonylContact O-C 3.51Å; E602-I605 PolarHBondContact O-N 2.92Å; E602-I605 VanDerWaalsContact O-N 3.1Å; V603-I605 VanDerWaalsContact C-N 3.25Å; V603-I605 PolarHBondContact O-N 3.02Å; I605-W607 HydrophobicContact CB-CZ2 4.15Å; I605-W607 HydrophobicContact CG2-CZ2 4.05Å; I605-W607 PolarHBondContact O-N 3.03Å; I605-S608 WeakPolarHBondContact O-CB 3.21Å; I605-S608 PolarHBondContact O-N 2.89Å; I605-S608 PolarHBondContact O-OG 2.8Å
606S97.5Very high96.5Very high0 Ų033.4 Ų33.40%016%0.164CC..G310 helixtrans-59-14.9-175.955.20000115.1E602 S608 R609 Y610 F640 E641E602-S606 PolarHBondContact O-N 2.98Å; E602-S606 VanDerWaalsContact O-N 3.15Å; S606-S608 VanDerWaalsContact C-N 3.3Å; S606-R609 WeakPolarHBondContact O-CD 3.25Å; S606-R609 WeakPolarHBondContact O-CG 3.39Å; S606-Y610 WeakPolarHBondContact O-CE2 3.45Å; S606-F640 PolarHBondContact OG-N 2.81Å; S606-E641 PolarHBondContact OG-N 3.01Å
607W98.3Very high96.7Very high0 Ų030.7 Ų30.70%014%0.144CC..G310 helixtrans-64.5-30.1168.453.3-98.9000113.3E343 I345 L502 H504 I605 R609 Y610 F640 T660E343-W607 HydrophobicContact CB-CH2 4.45Å; E343-W607 HydrophobicContact CB-CZ2 3.84Å; E343-W607 HydrophobicContact CG-CH2 4.28Å; E343-W607 HydrophobicContact CG-CZ2 3.51Å; I345-W607 HydrophobicContact CB-CH2 4.45Å; I345-W607 HydrophobicContact CD1-CH2 3.91Å; I345-W607 HydrophobicContact CD1-CZ2 4.43Å; I345-W607 HydrophobicContact CG1-CH2 4.04Å; I345-W607 HydrophobicContact CG2-CH2 3.66Å; I345-W607 HydrophobicContact CG2-CZ2 3.55Å; L502-W607 HydrophobicContact CB-CH2 4.14Å; L502-W607 HydrophobicContact CB-CZ3 3.92Å; H504-W607 HydrophobicContact CB-CD2 3.85Å; H504-W607 HydrophobicContact CB-CE3 3.55Å; H504-W607 HydrophobicContact CB-CG 4.47Å; H504-W607 HydrophobicContact CB-CH2 4.32Å; H504-W607 HydrophobicContact CB-CZ3 3.81Å; H504-W607 AromaticContact CD2-CE3 3.82Å; H504-W607 AromaticContact CG-CD2 3.84Å; H504-W607 AromaticContact CG-CE3 3.69Å; H504-W607 AromaticContact ND1-CG 3.89Å; I605-W607 HydrophobicContact CB-CZ2 4.15Å; I605-W607 HydrophobicContact CG2-CZ2 4.05Å; I605-W607 PolarHBondContact O-N 3.03Å; W607-R609 PolarHBondContact O-N 3.03Å; W607-Y610 PolarHBondContact O-N 2.95Å; W607-F640 HydrophobicContact CB-CB 3.85Å; W607-F640 HydrophobicContact CB-CD1 3.6Å; W607-F640 HydrophobicContact CB-CD2 4.37Å; W607-F640 HydrophobicContact CB-CE1 4.22Å; W607-F640 HydrophobicContact CB-CG 3.66Å; W607-T660 HydrophobicContact CE3-CG2 4.18Å; W607-T660 HydrophobicContact CZ3-CG2 3.98Å; W607-T660 PolarHBondContact O-OG1 3.33Å
608S97.6Very high96.9Very high0 Ų029.8 Ų29.80%014%0.137CC..G310 helixtrans-63-12.2-179.968.70000114.2F558 I605 S606 Y610F558-S608 VanDerWaalsContact CD2-O 3.23Å; F558-S608 WeakPolarHBondContact CD2-O 3.46Å; F558-S608 VanDerWaalsContact CE2-O 3.23Å; F558-S608 WeakPolarHBondContact CE2-O 3.4Å; I605-S608 WeakPolarHBondContact O-CB 3.21Å; I605-S608 PolarHBondContact O-N 2.89Å; I605-S608 PolarHBondContact O-OG 2.8Å; S606-S608 VanDerWaalsContact C-N 3.3Å; S608-Y610 PolarHBondContact O-N 2.92Å
609R96.8Very high97.1Very high24 Ų2430.7 Ų30.79%0.09113%0.13CC..G310 helixtrans-70.2-23.5174-58.6171.6-177.3163.97.2112.5R557 F558 E602 S606 W607 E641R557-R609 VanDerWaalsContact CA-O 3.31Å; R557-R609 WeakPolarHBondContact CA-O 3.42Å; F558-R609 PolarHBondContact N-O 3.39Å; F558-R609 VanDerWaalsContact N-O 3.07Å; E602-R609 WeakPolarHBondContact OE1-CG 3.26Å; E602-R609 IonicContact OE1-CZ 2.58Å; E602-R609 IonicContact OE1-NE 3.16Å; E602-R609 PolarHBondContact OE1-NE 2.75Å; E602-R609 IonicContact OE1-NH2 2.88Å; E602-R609 PolarHBondContact OE1-NH2 2.98Å; E602-R609 IonicContact OE2-CZ 3.4Å; E602-R609 IonicContact OE2-NE 2.66Å; E602-R609 PolarHBondContact OE2-NE 2.61Å; E602-R609 IonicContact OE2-NH2 2.79Å; E602-R609 PolarHBondContact OE2-NH2 3.14Å; S606-R609 WeakPolarHBondContact O-CD 3.25Å; S606-R609 WeakPolarHBondContact O-CG 3.39Å; W607-R609 PolarHBondContact O-N 3.03Å; R609-E641 IonicContact CZ-OE2 3.51Å; R609-E641 IonicContact NH1-OE1 3.82Å; R609-E641 IonicContact NH1-OE2 2.73Å; R609-E641 PolarHBondContact NH1-OE2 3.33Å
610Y98.1Very high97Very high2 Ų229.1 Ų29.11%0.00814%0.138CC..  trans-121.7112.7-162-54.8-76.8000111.1A555 F556 R557 S606 W607 S608 L612 A613 F640 E641 I644 T660A555-Y610 HydrophobicContact CB-CD1 4.08Å; A555-Y610 HydrophobicContact CB-CE1 3.92Å; F556-Y610 VanDerWaalsContact O-CA 3.23Å; F556-Y610 WeakPolarHBondContact O-CA 3.19Å; F556-Y610 WeakPolarHBondContact O-CB 3.29Å; F556-Y610 WeakPolarHBondContact O-CD1 3.41Å; R557-Y610 HydrophobicContact CG-CD1 3.69Å; R557-Y610 HydrophobicContact CG-CE1 3.45Å; R557-Y610 VanDerWaalsContact CG-CE1 3.45Å; R557-Y610 PolarHBondContact NH2-OH 2.85Å; S606-Y610 WeakPolarHBondContact O-CE2 3.45Å; W607-Y610 PolarHBondContact O-N 2.95Å; S608-Y610 PolarHBondContact O-N 2.92Å; Y610-L612 PolarHBondContact O-N 3.09Å; Y610-A613 HydrophobicContact CG-CB 4.4Å; Y610-F640 HydrophobicContact CD2-CD1 4.19Å; Y610-F640 AromaticContact CD2-CE1 3.91Å; Y610-F640 HydrophobicContact CD2-CE1 3.91Å; Y610-F640 HydrophobicContact CE2-CD1 4.47Å; Y610-F640 HydrophobicContact CE2-CE1 4.42Å; Y610-E641 WeakPolarHBondContact CE2-OE2 3.46Å; Y610-E641 PolarHBondContact OH-OE1 2.66Å; Y610-E641 PolarHBondContact OH-OE2 3.25Å; Y610-I644 HydrophobicContact CD2-CD1 4.06Å; Y610-I644 HydrophobicContact CE1-CD1 4.36Å; Y610-I644 HydrophobicContact CE2-CD1 3.73Å; Y610-T660 WeakPolarHBondContact O-CB 3.4Å; Y610-T660 PolarHBondContact O-OG1 3.42Å
611P98.2Very high97.1Very high10 Ų1023.5 Ų23.57%0.06512%0.118CC..SBendtrans-56.2-37.5163.120.9-34.4000111.4F556 F558 F562 F587 T660F556-P611 HydrophobicContact CB-CG 4.41Å; F556-P611 WeakPolarHBondContact O-CD 3.44Å; F558-P611 HydrophobicContact CD1-CB 4.26Å; F558-P611 HydrophobicContact CD1-CG 4.13Å; F558-P611 HydrophobicContact CE1-CB 3.67Å; F558-P611 HydrophobicContact CE1-CG 4.05Å; F558-P611 HydrophobicContact CZ-CB 3.84Å; F558-P611 HydrophobicContact CZ-CG 4.37Å; F562-P611 HydrophobicContact CD2-CB 4.23Å; F562-P611 HydrophobicContact CD2-CG 3.79Å; F562-P611 HydrophobicContact CE2-CB 3.99Å; F562-P611 HydrophobicContact CE2-CG 3.84Å; F587-P611 HydrophobicContact CE1-CB 4.23Å; F587-P611 WeakPolarHBondContact CE1-O 3.28Å; F587-P611 VanDerWaalsContact CZ-O 3.3Å; F587-P611 WeakPolarHBondContact CZ-O 3.47Å; P611-T660 PolarHBondContact O-N 3.15Å
612L98.7Very high97.1Very high0 Ų024.7 Ų24.70%013%0.129CC..EExtended strand (participates in β ladder)trans-145.8132.9176-173.579.8000110.7F518 F556 F562 V566 I585 F587 Y610 V614 A657 W658 V659F518-L612 HydrophobicContact CZ-CD2 4.15Å; F556-L612 HydrophobicContact CD2-CB 4.1Å; F556-L612 HydrophobicContact CD2-CD2 3.91Å; F556-L612 HydrophobicContact CD2-CG 4.41Å; F556-L612 HydrophobicContact CE2-CD2 3.97Å; F556-L612 PolarHBondContact N-O 3.36Å; F562-L612 HydrophobicContact CE2-CB 3.87Å; F562-L612 HydrophobicContact CZ-CB 4.01Å; F562-L612 HydrophobicContact CZ-CD2 4.46Å; V566-L612 HydrophobicContact CB-CD2 4.3Å; V566-L612 HydrophobicContact CG1-CD2 3.23Å; V566-L612 HydrophobicContact CG2-CD2 4.07Å; I585-L612 HydrophobicContact CD1-CD1 4.15Å; F587-L612 HydrophobicContact CE2-CB 4.45Å; F587-L612 HydrophobicContact CE2-CD1 4.4Å; F587-L612 HydrophobicContact CZ-CB 3.87Å; F587-L612 HydrophobicContact CZ-CD1 4Å; F587-L612 HydrophobicContact CZ-CG 4.47Å; Y610-L612 PolarHBondContact O-N 3.09Å; L612-V614 HydrophobicContact CD2-CG2 4.43Å; L612-A657 HydrophobicContact CD1-CB 4.17Å; L612-W658 VanDerWaalsContact CA-O 3.3Å; L612-W658 WeakPolarHBondContact CA-O 3.47Å; L612-V659 HydrophobicContact CD1-CG2 3.76Å
613A98.8Very high97.2Very high1 Ų125.5 Ų25.51%0.00813%0.134CC..EExtended strand (participates in β ladder)trans-128.9149.7160.400000110.8A554 A555 Y610 F640 I644 W658A554-A613 WeakPolarHBondContact O-CA 3.47Å; A555-A613 HydrophobicContact CB-CB 4.2Å; Y610-A613 HydrophobicContact CG-CB 4.4Å; A613-F640 HydrophobicContact CB-CE1 4.06Å; A613-F640 HydrophobicContact CB-CZ 3.94Å; A613-I644 HydrophobicContact CB-CD1 3.72Å; A613-I644 HydrophobicContact CB-CG1 4.39Å; A613-W658 PolarHBondContact N-O 2.77Å; A613-W658 PolarHBondContact O-N 2.99Å
614V98.9Very high97.3Very high0 Ų023.3 Ų23.30%012%0.121CC..EExtended strand (participates in β ladder)trans-119.5122.9175.8-1730000108.8F518 E551 A554 F568 L612 I650 L655 V656F518-V614 HydrophobicContact CD1-CG2 4.02Å; F518-V614 HydrophobicContact CD2-CG2 4.3Å; F518-V614 HydrophobicContact CE1-CG2 4.18Å; F518-V614 HydrophobicContact CE2-CG2 4.43Å; F518-V614 HydrophobicContact CG-CG2 4.12Å; F518-V614 HydrophobicContact CZ-CG2 4.39Å; E551-V614 WeakPolarHBondContact CA-O 3.2Å; A554-V614 HydrophobicContact CB-CB 3.73Å; A554-V614 HydrophobicContact CB-CG2 3.93Å; A554-V614 PolarHBondContact O-N 2.78Å; F568-V614 HydrophobicContact CE1-CG1 3.7Å; F568-V614 HydrophobicContact CE1-CG2 4.09Å; F568-V614 HydrophobicContact CZ-CB 4.47Å; F568-V614 HydrophobicContact CZ-CG1 4.07Å; F568-V614 HydrophobicContact CZ-CG2 3.58Å; L612-V614 HydrophobicContact CD2-CG2 4.43Å; V614-I650 HydrophobicContact CG1-CD1 4.39Å; V614-L655 HydrophobicContact CG1-CB 4.25Å; V614-L655 HydrophobicContact CG1-CD1 4.19Å; V614-V656 WeakPolarHBondContact CA-O 3.48Å
615T98.9Very high97.4Very high1 Ų123.4 Ų23.41%0.00612%0.121CC..EExtended strand (participates in β ladder)trans-120.4161.2178.272.20000110.4E551 I644 V656 W658E551-T615 WeakPolarHBondContact OE1-CA 3.46Å; T615-I644 HydrophobicContact CG2-CG1 4.15Å; T615-V656 PolarHBondContact N-O 2.95Å; T615-V656 PolarHBondContact O-N 2.94Å; T615-W658 PolarHBondContact OG1-NE1 3.26Å
616R98.6Very high97.4Very high90 Ų9023.8 Ų23.834%0.3412%0.124SC..EExtended strand (participates in β ladder)trans-74.9137.7167-172.7179.5-173.7-171.36.8109.5E551 R618 E648 Q653 D654E551-R616 PolarHBondContact OE1-N 2.77Å; R616-R618 PolarHBondContact O-N 2.74Å; R616-E648 IonicContact NH1-OE1 3.65Å; R616-E648 PolarHBondContact NH1-OE1 2.83Å; R616-Q653 HydrophobicContact CG-CB 4.38Å; R616-Q653 VanDerWaalsContact CZ-OE1 3.29Å; R616-D654 WeakPolarHBondContact CA-O 3.4Å
617H98.4Very high97.4Very high32 Ų3223.9 Ų23.915%0.14812%0.124CC..  trans-60.1131.7176.4175.2-81.7000111.7D508 D619 D654 V656D508-H617 IonicContact OD2-CD2 3.83Å; H617-D619 IonicContact CE1-OD1 3.82Å; H617-D619 PolarHBondContact CE1-OD1 2.83Å; H617-D654 HydrophobicContact CB-CB 3.93Å; H617-D654 VanDerWaalsContact CB-CG 3.43Å; H617-D654 VanDerWaalsContact CB-OD1 3.27Å; H617-D654 WeakPolarHBondContact CB-OD1 3.44Å; H617-D654 IonicContact CG-OD1 2.67Å; H617-D654 IonicContact CG-OD2 3.88Å; H617-D654 PolarHBondContact N-O 2.77Å; H617-D654 IonicContact ND1-OD2 2.86Å; H617-V656 HydrophobicContact CB-CG2 3.85Å
618R96.7Very high97.4Very high104 Ų10424.1 Ų24.139%0.39213%0.125SC..  trans-138.9133.1169.5-69.3-178.4170.1-97.7-2.7110.2R616 S620 E621 E648R616-R618 PolarHBondContact O-N 2.74Å; R618-S620 PolarHBondContact O-N 2.81Å; R618-S620 VanDerWaalsContact O-N 3.11Å; R618-E621 HydrophobicContact CB-CB 4.13Å; R618-E621 HydrophobicContact CB-CG 3.98Å; R618-E621 PolarHBondContact O-N 2.87Å; R618-E648 IonicContact CZ-OE1 3.82Å; R618-E648 IonicContact CZ-OE2 3.41Å; R618-E648 IonicContact NE-OE1 3.55Å; R618-E648 IonicContact NE-OE2 3.24Å; R618-E648 PolarHBondContact NE-OE2 3.16Å; R618-E648 IonicContact NH2-OE1 3.38Å; R618-E648 PolarHBondContact NH2-OE1 3.17Å; R618-E648 IonicContact NH2-OE2 2.77Å; R618-E648 PolarHBondContact NH2-OE2 3.06Å
619D94.6Very high97.4Very high70 Ų7024.1 Ų24.137%0.37413%0.125SC..G310 helixtrans-59.3-25.7175.8-69.1-39.8000112.1K77 H78 H617 E621K77-D619 PolarHBondContact N-OD1 2.98Å; H78-D619 IonicContact ND1-OD2 3.72Å; H617-D619 IonicContact CE1-OD1 3.82Å; H617-D619 PolarHBondContact CE1-OD1 2.83Å; D619-E621 VanDerWaalsContact C-N 3.32Å
620S93.1Very high97.5Very high96 Ų9623 Ų2367%0.67112%0.121SC*.G310 helixtrans-78.8-10.1176.358.50000114.6R618R618-S620 PolarHBondContact O-N 2.81Å; R618-S620 VanDerWaalsContact O-N 3.11Å
621E96.3Very high97.5Very high8 Ų823.1 Ų23.14%0.03712%0.121CC..G310 helixtrans-114.941.2-176.9-60.2-178.6170.900109.5R618 D619 T623 Y643R618-E621 HydrophobicContact CB-CB 4.13Å; R618-E621 HydrophobicContact CB-CG 3.98Å; R618-E621 PolarHBondContact O-N 2.87Å; D619-E621 VanDerWaalsContact C-N 3.32Å; E621-T623 VanDerWaalsContact C-N 3.3Å; E621-T623 PolarHBondContact O-N 3.48Å; E621-Y643 HydrophobicContact CB-CD1 4.11Å; E621-Y643 HydrophobicContact CB-CD2 4.13Å; E621-Y643 HydrophobicContact CB-CE1 3.85Å; E621-Y643 HydrophobicContact CB-CE2 3.83Å; E621-Y643 HydrophobicContact CB-CG 4.26Å; E621-Y643 VanDerWaalsContact CD-CD1 3.43Å; E621-Y643 HydrophobicContact CG-CD1 3.65Å; E621-Y643 HydrophobicContact CG-CE1 3.55Å; E621-Y643 HydrophobicContact CG-CE2 4.42Å; E621-Y643 HydrophobicContact CG-CG 4.18Å
622A94.8Very high97.4Very high34 Ų3422.9 Ų22.928%0.28112%0.12SC..  trans-67-28.5-170.300000113.8
623T97.5Very high97.4Very high17 Ų1723 Ų2310%0.10412%0.12CC..  trans-137.4149-175.7600000111.5E621 S625 V638 Y643E621-T623 VanDerWaalsContact C-N 3.3Å; E621-T623 PolarHBondContact O-N 3.48Å; T623-S625 PolarHBondContact OG1-O 3.49Å; T623-S625 VanDerWaalsContact OG1-O 3.08Å; T623-V638 WeakPolarHBondContact O-CG1 3.23Å; T623-Y643 PolarHBondContact O-OH 3.36Å
624S98.3Very high97.2Very high0 Ų024 Ų240%012%0.124CC..SBendtrans-91.6-8.9176.667.30000114.7Q342 H504Q342-S624 VanDerWaalsContact CB-OG 3.25Å; Q342-S624 WeakPolarHBondContact CB-OG 3.41Å; H504-S624 PolarHBondContact CE1-OG 2.96Å; H504-S624 WeakPolarHBondContact ND1-CB 3.12Å; H504-S624 PolarHBondContact ND1-OG 2.88Å
625S97.8Very high97Very high3 Ų329.4 Ų29.42%0.02115%0.149CC..  trans-142.7177.6178.9-165.20000110.8E343 T623E343-S625 WeakPolarHBondContact OE2-CB 3.12Å; E343-S625 PolarHBondContact OE2-OG 2.8Å; T623-S625 PolarHBondContact OG1-O 3.49Å; T623-S625 VanDerWaalsContact OG1-O 3.08Å
626T97.3Very high96.8Very high8 Ų830.4 Ų30.45%0.04916%0.156CC..  trans-146161.7176.672.40000110.9F128 F628 T629 A637 V638F128-T626 HydrophobicContact CE1-CG2 4.01Å; F128-T626 HydrophobicContact CZ-CG2 4.46Å; T626-F628 PolarHBondContact O-N 3.19Å; T626-F628 VanDerWaalsContact O-N 3.11Å; T626-F628 PolarHBondContact OG1-N 3.3Å; T626-T629 PolarHBondContact N-OG1 3.45Å; T626-T629 WeakPolarHBondContact O-CB 3.41Å; T626-T629 PolarHBondContact O-N 3.12Å; T626-T629 PolarHBondContact O-OG1 3.21Å; T626-T629 PolarHBondContact OG1-N 3.24Å; T626-T629 PolarHBondContact OG1-OG1 3.23Å; T626-T629 VanDerWaalsContact OG1-OG1 3.06Å; T626-A637 HydrophobicContact CG2-CB 4.31Å; T626-V638 HydrophobicContact CG2-CB 3.83Å; T626-V638 HydrophobicContact CG2-CG2 3.39Å
627I97.9Very high96.6Very high1 Ų127.6 Ų27.61%0.00515%0.152CC..THydrogen-bonded Turntrans-65.6-11.2173.375.6176.7000113.5L68 L69 I98 P140 A363 G364L68-I627 HydrophobicContact CD2-CD1 4.21Å; L69-I627 HydrophobicContact CD2-CD1 4.47Å; I98-I627 HydrophobicContact CD1-CD1 3.29Å; I98-I627 HydrophobicContact CD1-CG1 4.24Å; P140-I627 HydrophobicContact CG-CB 4.27Å; P140-I627 HydrophobicContact CG-CD1 3.94Å; P140-I627 HydrophobicContact CG-CG1 4.12Å; A363-I627 WeakPolarHBondContact O-CA 3.47Å; A363-I627 WeakPolarHBondContact O-CB 3.42Å; A363-I627 WeakPolarHBondContact O-CG2 3.28Å; G364-I627 WeakPolarHBondContact CA-O 3.43Å
628F97.9Very high96.4Very high5 Ų526.7 Ų26.72%0.02215%0.149CC..THydrogen-bonded Turntrans-88.1-21-179-48.9-51.4000112I98 I109 E111 F128 V134 S138 T626 Q630 N631 D632 A637I98-F628 HydrophobicContact CD1-CZ 4.14Å; I98-F628 HydrophobicContact CG2-CE1 4.33Å; I98-F628 HydrophobicContact CG2-CZ 4.19Å; I109-F628 HydrophobicContact CD1-CD1 4.21Å; I109-F628 HydrophobicContact CD1-CE1 3.47Å; I109-F628 VanDerWaalsContact CD1-CE1 3.47Å; I109-F628 HydrophobicContact CD1-CZ 4.25Å; I109-F628 HydrophobicContact CG1-CE1 4.12Å; I109-F628 HydrophobicContact CG1-CZ 4.47Å; I109-F628 HydrophobicContact CG2-CE1 4.41Å; E111-F628 HydrophobicContact CG-CE2 4.47Å; E111-F628 HydrophobicContact CG-CZ 4.33Å; E111-F628 VanDerWaalsContact OE1-CE2 3.24Å; E111-F628 WeakPolarHBondContact OE1-CE2 3.37Å; F128-F628 HydrophobicContact CE2-CE2 4.11Å; F128-F628 HydrophobicContact CZ-CD2 4.25Å; F128-F628 AromaticContact CZ-CE2 3.89Å; F128-F628 HydrophobicContact CZ-CE2 3.89Å; V134-F628 HydrophobicContact CG1-CB 4.08Å; V134-F628 HydrophobicContact CG1-CD1 3.97Å; V134-F628 HydrophobicContact CG1-CD2 3.75Å; V134-F628 HydrophobicContact CG1-CE1 4.39Å; V134-F628 HydrophobicContact CG1-CE2 4.14Å; V134-F628 HydrophobicContact CG1-CG 3.64Å; V134-F628 HydrophobicContact CG1-CZ 4.46Å; V134-F628 HydrophobicContact CG2-CD2 4.07Å; V134-F628 HydrophobicContact CG2-CE2 4.07Å; S138-F628 WeakPolarHBondContact O-CA 3.33Å; T626-F628 PolarHBondContact O-N 3.19Å; T626-F628 VanDerWaalsContact O-N 3.11Å; T626-F628 PolarHBondContact OG1-N 3.3Å; F628-Q630 VanDerWaalsContact C-N 3.29Å; F628-Q630 PolarHBondContact O-N 3.24Å; F628-N631 PolarHBondContact O-N 2.91Å; F628-D632 PolarHBondContact O-N 2.88Å; F628-A637 HydrophobicContact CD2-CB 4.3Å
629T97.8Very high96.3Very high0 Ų022.7 Ų22.70%014%0.136CC..THydrogen-bonded Turntrans-63.2-32.6-171.8-52.70000112.6I361 G604 T626 N631 D632 P633 P636I361-T629 HydrophobicContact CD1-CG2 3.99Å; I361-T629 HydrophobicContact CG2-CG2 4.37Å; G604-T629 WeakPolarHBondContact O-CG2 3.49Å; T626-T629 PolarHBondContact N-OG1 3.45Å; T626-T629 WeakPolarHBondContact O-CB 3.41Å; T626-T629 PolarHBondContact O-N 3.12Å; T626-T629 PolarHBondContact O-OG1 3.21Å; T626-T629 PolarHBondContact OG1-N 3.24Å; T626-T629 PolarHBondContact OG1-OG1 3.23Å; T626-T629 VanDerWaalsContact OG1-OG1 3.06Å; T629-N631 VanDerWaalsContact C-N 3.34Å; T629-N631 PolarHBondContact O-N 2.95Å; T629-D632 CarbonylContact O-C 3.33Å; T629-P633 VanDerWaalsContact O-CA 3.23Å; T629-P633 WeakPolarHBondContact O-CA 3.37Å; T629-P633 WeakPolarHBondContact O-CB 3.36Å; T629-P633 VanDerWaalsContact O-CD 3.25Å; T629-P633 WeakPolarHBondContact O-CD 3.37Å; T629-P636 HydrophobicContact CG2-CB 4.35Å
630Q98.4Very high96.4Very high1 Ų119.4 Ų19.41%0.00512%0.119CC..THydrogen-bonded Turntrans-60.4-42-179.517464.694.500113A187 P188 K359 I361 F628A187-Q630 VanDerWaalsContact CB-CD 3.41Å; A187-Q630 HydrophobicContact CB-CG 3.81Å; A187-Q630 VanDerWaalsContact CB-NE2 3.28Å; P188-Q630 WeakPolarHBondContact CA-O 3.4Å; P188-Q630 VanDerWaalsContact CB-O 3.3Å; P188-Q630 WeakPolarHBondContact CB-O 3.39Å; K359-Q630 PolarHBondContact O-NE2 3.03Å; I361-Q630 HydrophobicContact CB-CB 4.2Å; I361-Q630 PolarHBondContact O-OE1 3.01Å; F628-Q630 VanDerWaalsContact C-N 3.29Å; F628-Q630 PolarHBondContact O-N 3.24Å
631N98.2Very high96.6Very high4 Ų415.9 Ų15.92%0.0219%0.092CC..THydrogen-bonded Turntrans-97.9-11-173.6-66.2-33.2000112.5R139 R189 F628 T629R139-N631 PolarHBondContact O-ND2 3.28Å; R189-N631 WeakPolarHBondContact CD-OD1 3.42Å; R189-N631 WeakPolarHBondContact CG-OD1 3.16Å; R189-N631 PolarHBondContact NE-OD1 2.81Å; F628-N631 PolarHBondContact O-N 2.91Å; T629-N631 VanDerWaalsContact C-N 3.34Å; T629-N631 PolarHBondContact O-N 2.95Å
632D97.3Very high96.6Very high6 Ų617.9 Ų17.93%0.03210%0.103CC..  trans-141.571.6166.6-168.2-2.6000111.5F628 T629 W634 E635F628-D632 PolarHBondContact O-N 2.88Å; T629-D632 CarbonylContact O-C 3.33Å; D632-W634 PolarHBondContact O-N 2.9Å; D632-W634 PolarHBondContact OD1-N 3.24Å; D632-E635 PolarHBondContact OD1-N 2.98Å
633P97.3Very high96.7Very high1 Ų116.9 Ų16.91%0.0069%0.092CC..SBendtrans-74.3-10.6177.431-37000112.7P188 I361 E601 G604 T629P188-P633 HydrophobicContact CB-CG 3.88Å; P188-P633 HydrophobicContact CG-CG 4.22Å; I361-P633 HydrophobicContact CD1-CB 4.26Å; E601-P633 HydrophobicContact CB-CB 4.12Å; E601-P633 HydrophobicContact CB-CG 3.97Å; E601-P633 HydrophobicContact CG-CG 3.97Å; G604-P633 WeakPolarHBondContact CA-O 3.32Å; G604-P633 PolarHBondContact N-O 3.29Å; T629-P633 VanDerWaalsContact O-CA 3.23Å; T629-P633 WeakPolarHBondContact O-CA 3.37Å; T629-P633 WeakPolarHBondContact O-CB 3.36Å; T629-P633 VanDerWaalsContact O-CD 3.25Å; T629-P633 WeakPolarHBondContact O-CD 3.37Å
634W96.5Very high96.7Very high24 Ų2416.2 Ų16.29%0.0919%0.088CC..SBendtrans-81.9-40.5-177.9-54-78.8000111.6P188 G190 L191 A192 P193 E601 D632 P636P188-W634 HydrophobicContact CB-CH2 3.86Å; P188-W634 HydrophobicContact CB-CZ2 4.23Å; P188-W634 HydrophobicContact CG-CH2 4.34Å; P188-W634 HydrophobicContact CG-CZ2 4.23Å; G190-W634 VanDerWaalsContact O-CH2 3.26Å; G190-W634 WeakPolarHBondContact O-CH2 3.3Å; G190-W634 WeakPolarHBondContact O-CZ2 3.14Å; L191-W634 VanDerWaalsContact C-CZ2 3.5Å; A192-W634 VanDerWaalsContact O-CE3 3.31Å; A192-W634 VanDerWaalsContact O-CZ3 3.24Å; A192-W634 WeakPolarHBondContact O-CZ3 3.3Å; P193-W634 HydrophobicContact CG-CB 3.67Å; E601-W634 HydrophobicContact CG-CZ2 4.23Å; E601-W634 PolarHBondContact OE1-NE1 3.07Å; D632-W634 PolarHBondContact O-N 2.9Å; D632-W634 PolarHBondContact OD1-N 3.24Å; W634-P636 VanDerWaalsContact C-CD 3.41Å; W634-P636 WeakPolarHBondContact O-CD 3.15Å
635E94.5Very high96.6Very high112 Ų11222.5 Ų22.552%0.52311%0.111SC..SBendtrans-119.864.3172.7-74-169.2-169.600112.1P193 D632P193-E635 HydrophobicContact CB-CB 4.31Å; P193-E635 HydrophobicContact CB-CG 4.06Å; P193-E635 HydrophobicContact CG-CB 4.33Å; P193-E635 HydrophobicContact CG-CG 3.7Å; D632-E635 PolarHBondContact OD1-N 2.98Å
636P94.2Very high96.5Very high23 Ų2325.3 Ų25.315%0.14913%0.126CC..  trans-67.5142.3-172.232.9-40.4000112V603 T629 W634 V638V603-P636 HydrophobicContact CG1-CG 4.04Å; T629-P636 HydrophobicContact CG2-CB 4.35Å; W634-P636 VanDerWaalsContact C-CD 3.41Å; W634-P636 WeakPolarHBondContact O-CD 3.15Å; P636-V638 WeakPolarHBondContact CB-O 3.48Å; P636-V638 PolarHBondContact O-N 3.1Å
637A93.3Very high96.5Very high30 Ų3027.6 Ų27.625%0.24814%0.138CC..SBendtrans-62.3-25.3174.900000113F128 V134 T626 F628F128-A637 HydrophobicContact CD1-CB 3.99Å; F128-A637 HydrophobicContact CD2-CB 4.1Å; F128-A637 HydrophobicContact CE1-CB 3.98Å; F128-A637 HydrophobicContact CE2-CB 4.11Å; F128-A637 HydrophobicContact CG-CB 4.06Å; F128-A637 HydrophobicContact CZ-CB 4.05Å; V134-A637 HydrophobicContact CG2-CB 4.29Å; T626-A637 HydrophobicContact CG2-CB 4.31Å; F628-A637 HydrophobicContact CD2-CB 4.3Å
638V94.8Very high96.6Very high14 Ų1428.9 Ų28.99%0.08514%0.144CC..  trans-129.2127.1173.8171.40000109.5F128 T623 T626 P636 Y643F128-V638 HydrophobicContact CD1-CG2 4.04Å; F128-V638 HydrophobicContact CE1-CG2 4.05Å; T623-V638 WeakPolarHBondContact O-CG1 3.23Å; T626-V638 HydrophobicContact CG2-CB 3.83Å; T626-V638 HydrophobicContact CG2-CG2 3.39Å; P636-V638 WeakPolarHBondContact CB-O 3.48Å; P636-V638 PolarHBondContact O-N 3.1Å; V638-Y643 WeakPolarHBondContact CG1-OH 3.24Å
639S94.5Very high96.6Very high20 Ų2032.4 Ų32.414%0.1416%0.163CC..  trans-118.8113.5171-179.50000109.7E641 D642S639-E641 VanDerWaalsContact C-N 3.27Å; S639-E641 PolarHBondContact O-N 2.79Å; S639-D642 WeakPolarHBondContact O-CB 3.31Å; S639-D642 PolarHBondContact O-N 2.86Å; S639-D642 VanDerWaalsContact O-N 3.1Å
640F97.8Very high96.7Very high1 Ų132.4 Ų32.40%0.00416%0.163CC..THydrogen-bonded Turntrans-60.9-33.6-177.5179.3-103.8000113.5S606 W607 Y610 A613 D642 Y643 I644 W658S606-F640 PolarHBondContact OG-N 2.81Å; W607-F640 HydrophobicContact CB-CB 3.85Å; W607-F640 HydrophobicContact CB-CD1 3.6Å; W607-F640 HydrophobicContact CB-CD2 4.37Å; W607-F640 HydrophobicContact CB-CE1 4.22Å; W607-F640 HydrophobicContact CB-CG 3.66Å; Y610-F640 HydrophobicContact CD2-CD1 4.19Å; Y610-F640 AromaticContact CD2-CE1 3.91Å; Y610-F640 HydrophobicContact CD2-CE1 3.91Å; Y610-F640 HydrophobicContact CE2-CD1 4.47Å; Y610-F640 HydrophobicContact CE2-CE1 4.42Å; A613-F640 HydrophobicContact CB-CE1 4.06Å; A613-F640 HydrophobicContact CB-CZ 3.94Å; F640-D642 PolarHBondContact O-N 3.32Å; F640-D642 VanDerWaalsContact O-N 3.07Å; F640-Y643 AromaticContact CD2-CD2 3.54Å; F640-Y643 HydrophobicContact CD2-CD2 3.54Å; F640-Y643 AromaticContact CD2-CE2 3.97Å; F640-Y643 HydrophobicContact CD2-CE2 3.97Å; F640-Y643 HydrophobicContact CD2-CG 4.36Å; F640-Y643 AromaticContact CE2-CD2 3.79Å; F640-Y643 HydrophobicContact CE2-CD2 3.79Å; F640-Y643 HydrophobicContact CE2-CE2 4.49Å; F640-Y643 WeakPolarHBondContact O-CB 3.44Å; F640-Y643 PolarHBondContact O-N 2.9Å; F640-I644 HydrophobicContact CD1-CD1 4.23Å; F640-I644 HydrophobicContact CE1-CD1 3.6Å; F640-I644 HydrophobicContact CE1-CG1 4.49Å; F640-I644 HydrophobicContact CZ-CD1 4.17Å; F640-W658 HydrophobicContact CD2-CD2 4.41Å; F640-W658 HydrophobicContact CE2-CB 3.86Å; F640-W658 AromaticContact CE2-CD1 3.72Å; F640-W658 AromaticContact CE2-CD2 3.45Å; F640-W658 HydrophobicContact CE2-CD2 3.45Å; F640-W658 VanDerWaalsContact CE2-CD2 3.45Å; F640-W658 AromaticContact CE2-CE2 3.76Å; F640-W658 AromaticContact CE2-CE3 3.96Å; F640-W658 HydrophobicContact CE2-CE3 3.96Å; F640-W658 AromaticContact CE2-CG 3.4Å; F640-W658 HydrophobicContact CE2-CG 3.4Å; F640-W658 HydrophobicContact CE2-CZ2 4.46Å; F640-W658 AromaticContact CE2-NE1 3.91Å; F640-W658 HydrophobicContact CZ-CB 3.55Å; F640-W658 AromaticContact CZ-CD1 3.76Å; F640-W658 HydrophobicContact CZ-CD2 4.09Å; F640-W658 AromaticContact CZ-CG 3.52Å; F640-W658 HydrophobicContact CZ-CG 3.52Å
641E96.4Very high96.7Very high21 Ų2134.1 Ų34.110%0.09817%0.174CC..THydrogen-bonded Turntrans-56.4-27176.4-176.271.9-172.700112.6S606 R609 Y610 S639 Y643 I644 R645S606-E641 PolarHBondContact OG-N 3.01Å; R609-E641 IonicContact CZ-OE2 3.51Å; R609-E641 IonicContact NH1-OE1 3.82Å; R609-E641 IonicContact NH1-OE2 2.73Å; R609-E641 PolarHBondContact NH1-OE2 3.33Å; Y610-E641 WeakPolarHBondContact CE2-OE2 3.46Å; Y610-E641 PolarHBondContact OH-OE1 2.66Å; Y610-E641 PolarHBondContact OH-OE2 3.25Å; S639-E641 VanDerWaalsContact C-N 3.27Å; S639-E641 PolarHBondContact O-N 2.79Å; E641-Y643 PolarHBondContact O-N 2.96Å; E641-I644 PolarHBondContact O-N 3.07Å; E641-R645 WeakPolarHBondContact O-CB 3.34Å; E641-R645 PolarHBondContact O-N 2.56Å; E641-R645 VanDerWaalsContact O-N 3.1Å
642D95.6Very high96.7Very high50 Ų5036.7 Ų36.727%0.26719%0.187SC..Hα-helixtrans-67.5-19.6178.9-68.7-12.4000113S639 F640 I644 R645S639-D642 WeakPolarHBondContact O-CB 3.31Å; S639-D642 PolarHBondContact O-N 2.86Å; S639-D642 VanDerWaalsContact O-N 3.1Å; F640-D642 PolarHBondContact O-N 3.32Å; F640-D642 VanDerWaalsContact O-N 3.07Å; D642-I644 VanDerWaalsContact C-N 3.32Å; D642-R645 IonicContact OD1-CZ 3.38Å; D642-R645 VanDerWaalsContact OD1-CZ 3.25Å; D642-R645 IonicContact OD1-NH1 3.45Å; D642-R645 PolarHBondContact OD1-NH1 2.81Å; D642-R645 IonicContact OD1-NH2 3.33Å; D642-R645 PolarHBondContact OD1-NH2 3.39Å
643Y97.8Very high96.7Very high13 Ų1338.7 Ų38.75%0.05120%0.196CC..Hα-helixtrans-80.5-16.4178.5-54.6-7.5000112.3E621 T623 V638 F640 E641 N646 W658E621-Y643 HydrophobicContact CB-CD1 4.11Å; E621-Y643 HydrophobicContact CB-CD2 4.13Å; E621-Y643 HydrophobicContact CB-CE1 3.85Å; E621-Y643 HydrophobicContact CB-CE2 3.83Å; E621-Y643 HydrophobicContact CB-CG 4.26Å; E621-Y643 VanDerWaalsContact CD-CD1 3.43Å; E621-Y643 HydrophobicContact CG-CD1 3.65Å; E621-Y643 HydrophobicContact CG-CE1 3.55Å; E621-Y643 HydrophobicContact CG-CE2 4.42Å; E621-Y643 HydrophobicContact CG-CG 4.18Å; T623-Y643 PolarHBondContact O-OH 3.36Å; V638-Y643 WeakPolarHBondContact CG1-OH 3.24Å; F640-Y643 AromaticContact CD2-CD2 3.54Å; F640-Y643 HydrophobicContact CD2-CD2 3.54Å; F640-Y643 AromaticContact CD2-CE2 3.97Å; F640-Y643 HydrophobicContact CD2-CE2 3.97Å; F640-Y643 HydrophobicContact CD2-CG 4.36Å; F640-Y643 AromaticContact CE2-CD2 3.79Å; F640-Y643 HydrophobicContact CE2-CD2 3.79Å; F640-Y643 HydrophobicContact CE2-CE2 4.49Å; F640-Y643 WeakPolarHBondContact O-CB 3.44Å; F640-Y643 PolarHBondContact O-N 2.9Å; E641-Y643 PolarHBondContact O-N 2.96Å; Y643-N646 PolarHBondContact O-OD1 3.38Å; Y643-W658 HydrophobicContact CD2-CZ2 4.06Å; Y643-W658 HydrophobicContact CE2-CH2 4.18Å; Y643-W658 HydrophobicContact CE2-CZ2 4.12Å
644I98.1Very high96.8Very high4 Ų439.7 Ų39.72%0.02120%0.202CC..Hα-helixtrans-105.3-26.4-179.6-61165.4000110.5R552 A555 Y610 A613 T615 F640 E641 D642 N646 N647R552-I644 HydrophobicContact CG-CG2 3.91Å; R552-I644 WeakPolarHBondContact CG-O 3.35Å; A555-I644 HydrophobicContact CB-CD1 4.08Å; A555-I644 HydrophobicContact CB-CG2 3.86Å; Y610-I644 HydrophobicContact CD2-CD1 4.06Å; Y610-I644 HydrophobicContact CE1-CD1 4.36Å; Y610-I644 HydrophobicContact CE2-CD1 3.73Å; A613-I644 HydrophobicContact CB-CD1 3.72Å; A613-I644 HydrophobicContact CB-CG1 4.39Å; T615-I644 HydrophobicContact CG2-CG1 4.15Å; F640-I644 HydrophobicContact CD1-CD1 4.23Å; F640-I644 HydrophobicContact CE1-CD1 3.6Å; F640-I644 HydrophobicContact CE1-CG1 4.49Å; F640-I644 HydrophobicContact CZ-CD1 4.17Å; E641-I644 PolarHBondContact O-N 3.07Å; D642-I644 VanDerWaalsContact C-N 3.32Å; I644-N646 VanDerWaalsContact C-OD1 3.3Å; I644-N646 PolarHBondContact N-OD1 2.86Å; I644-N646 PolarHBondContact O-N 3.13Å; I644-N647 PolarHBondContact O-N 2.95Å; I644-N647 VanDerWaalsContact O-N 3.08Å
645R96.3Very high96.9Very high131 Ų13138.5 Ų38.549%0.49420%0.197SC..Hα-helixtrans-68-35.2-171.1-166.1178.8-55.6154.720.7113R552 E641 D642 N647R552-R645 PolarHBondContact NH2-O 3.15Å; E641-R645 WeakPolarHBondContact O-CB 3.34Å; E641-R645 PolarHBondContact O-N 2.56Å; E641-R645 VanDerWaalsContact O-N 3.1Å; D642-R645 IonicContact OD1-CZ 3.38Å; D642-R645 VanDerWaalsContact OD1-CZ 3.25Å; D642-R645 IonicContact OD1-NH1 3.45Å; D642-R645 PolarHBondContact OD1-NH1 2.81Å; D642-R645 IonicContact OD1-NH2 3.33Å; D642-R645 PolarHBondContact OD1-NH2 3.39Å; R645-N647 PolarHBondContact O-N 2.81Å
646N94.6Very high97.1Very high63 Ų6333.3 Ų33.334%0.33717%0.173SC..THydrogen-bonded Turntrans-56.6-27169.351.1-19000113.4E551 Y643 I644 E648E551-N646 VanDerWaalsContact OE2-CG 3.31Å; E551-N646 PolarHBondContact OE2-ND2 2.86Å; E551-N646 PolarHBondContact OE2-OD1 3.28Å; Y643-N646 PolarHBondContact O-OD1 3.38Å; I644-N646 VanDerWaalsContact C-OD1 3.3Å; I644-N646 PolarHBondContact N-OD1 2.86Å; I644-N646 PolarHBondContact O-N 3.13Å; N646-E648 VanDerWaalsContact C-N 3.32Å; N646-E648 HydrophobicContact CB-CG 4.19Å; N646-E648 PolarHBondContact ND2-OE2 3.38Å; N646-E648 PolarHBondContact O-N 3.18Å
647N98.4Very high97.4Very high55 Ų5532.2 Ų32.229%0.29417%0.166SC..  trans53.445.5173.2-168.747.3000113.3T550 E551 R552 I644 R645T550-N647 WeakPolarHBondContact CB-OD1 3.33Å; T550-N647 PolarHBondContact OG1-OD1 2.94Å; E551-N647 PolarHBondContact OE2-N 2.83Å; R552-N647 WeakPolarHBondContact CB-OD1 3.2Å; R552-N647 HydrophobicContact CG-CB 3.85Å; R552-N647 WeakPolarHBondContact CG-OD1 3.27Å; R552-N647 PolarHBondContact N-OD1 3.3Å; R552-N647 VanDerWaalsContact N-OD1 3.15Å; I644-N647 PolarHBondContact O-N 2.95Å; I644-N647 VanDerWaalsContact O-N 3.08Å; R645-N647 PolarHBondContact O-N 2.81Å
648E98.6Very high97.6Very high28 Ų2830.9 Ų30.913%0.13115%0.154CC..  trans-64.6161.1-178.6-65-17274.100112.2T550 E551 R616 R618 N646T550-E648 WeakPolarHBondContact CA-O 3.27Å; E551-E648 HydrophobicContact CG-CB 4.32Å; E551-E648 PolarHBondContact N-O 3.39Å; E551-E648 VanDerWaalsContact N-O 3.11Å; E551-E648 PolarHBondContact OE2-N 3.33Å; R616-E648 IonicContact NH1-OE1 3.65Å; R616-E648 PolarHBondContact NH1-OE1 2.83Å; R618-E648 IonicContact CZ-OE1 3.82Å; R618-E648 IonicContact CZ-OE2 3.41Å; R618-E648 IonicContact NE-OE1 3.55Å; R618-E648 IonicContact NE-OE2 3.24Å; R618-E648 PolarHBondContact NE-OE2 3.16Å; R618-E648 IonicContact NH2-OE1 3.38Å; R618-E648 PolarHBondContact NH2-OE1 3.17Å; R618-E648 IonicContact NH2-OE2 2.77Å; R618-E648 PolarHBondContact NH2-OE2 3.06Å; N646-E648 VanDerWaalsContact C-N 3.32Å; N646-E648 HydrophobicContact CB-CG 4.19Å; N646-E648 PolarHBondContact ND2-OE2 3.38Å; N646-E648 PolarHBondContact O-N 3.18Å
649N98.6Very high97.8Very high79 Ų7930.2 Ų30.242%0.42215%0.15SC..BIsolated β-bridgetrans-69.4133.7170173.780.5000110.2K549 V651 Q653K549-N649 WeakPolarHBondContact O-CA 3.4Å; K549-N649 PolarHBondContact O-OD1 3.24Å; N649-V651 PolarHBondContact ND2-N 2.85Å; N649-V651 PolarHBondContact ND2-O 3.32Å; N649-V651 VanDerWaalsContact ND2-O 3.1Å; N649-Q653 WeakPolarHBondContact O-CG 3.35Å
650I98.8Very high98Very high0 Ų029.2 Ų29.20%014%0.144CC..  trans-116.412.5178.760.1168.4000112.9F518 H548 K549 E551 A554 V614 L655F518-I650 HydrophobicContact CB-CD1 4.37Å; H548-I650 HydrophobicContact CB-CD1 4.26Å; H548-I650 WeakPolarHBondContact O-CD1 3.42Å; H548-I650 WeakPolarHBondContact O-CG1 3.39Å; K549-I650 VanDerWaalsContact C-CG1 3.49Å; K549-I650 WeakPolarHBondContact O-CG1 3.44Å; K549-I650 PolarHBondContact O-N 3.45Å; E551-I650 HydrophobicContact CG-CG2 3.55Å; A554-I650 HydrophobicContact CB-CD1 3.6Å; V614-I650 HydrophobicContact CG1-CD1 4.39Å; I650-L655 HydrophobicContact CB-CD1 4.5Å; I650-L655 HydrophobicContact CB-CD2 3.62Å; I650-L655 HydrophobicContact CG2-CD2 3.95Å
651V98.7Very high98.1Very high38 Ų3829.2 Ų29.223%0.2314%0.143CC..THydrogen-bonded Turntrans-84.9123.7175-175.90000109.9K549 N649 Q653K549-V651 HydrophobicContact CB-CG2 3.88Å; K549-V651 HydrophobicContact CG-CG2 3.82Å; N649-V651 PolarHBondContact ND2-N 2.85Å; N649-V651 PolarHBondContact ND2-O 3.32Å; N649-V651 VanDerWaalsContact ND2-O 3.1Å; V651-Q653 WeakPolarHBondContact O-CG 3.47Å; V651-Q653 PolarHBondContact O-N 3.34Å; V651-Q653 PolarHBondContact O-NE2 3.36Å
652N98.4Very high98.2Very high58 Ų5828.2 Ų28.231%0.3114%0.139SC..THydrogen-bonded Turntrans52.352178.4-165.567.3000112.1D515 N516 S517 P571D515-N652 WeakPolarHBondContact CB-OD1 3.34Å; N516-N652 CarbonylContact O-C 3.53Å; N516-N652 WeakPolarHBondContact O-CA 3.15Å; N516-N652 PolarHBondContact O-N 3.46Å; S517-N652 PolarHBondContact OG-N 2.9Å; P571-N652 HydrophobicContact CG-CB 4.18Å; P571-N652 WeakPolarHBondContact CG-OD1 3.48Å
653Q98.6Very high98.3Very high47 Ų4726.4 Ų26.422%0.2213%0.129CC..BIsolated β-bridgetrans-129.5168.2179.7-60.2-55-53.100110.6R514 N516 R616 N649 V651 L655R514-Q653 CarbonylContact O-C 3.44Å; N516-Q653 PolarHBondContact N-O 3.28Å; N516-Q653 PolarHBondContact O-N 2.77Å; N516-Q653 VanDerWaalsContact O-O 3.11Å; R616-Q653 HydrophobicContact CG-CB 4.38Å; R616-Q653 VanDerWaalsContact CZ-OE1 3.29Å; N649-Q653 WeakPolarHBondContact O-CG 3.35Å; V651-Q653 WeakPolarHBondContact O-CG 3.47Å; V651-Q653 PolarHBondContact O-N 3.34Å; V651-Q653 PolarHBondContact O-NE2 3.36Å; Q653-L655 HydrophobicContact CB-CD2 3.93Å; Q653-L655 WeakPolarHBondContact O-CG 3.2Å; Q653-L655 PolarHBondContact O-N 3.08Å
654D98.8Very high98.3Very high22 Ų2230.7 Ų30.712%0.11815%0.152CC..  trans-68110.6166-167.2-22000109.3K77 R514 R616 H617K77-D654 VanDerWaalsContact NZ-CG 3.32Å; K77-D654 IonicContact NZ-OD1 3.72Å; K77-D654 PolarHBondContact NZ-OD1 3.07Å; K77-D654 IonicContact NZ-OD2 3.19Å; K77-D654 PolarHBondContact NZ-OD2 3.27Å; R514-D654 HydrophobicContact CB-CB 4.18Å; R514-D654 WeakPolarHBondContact CD-OD2 3.48Å; R514-D654 WeakPolarHBondContact O-CA 3.44Å; R514-D654 PolarHBondContact O-N 3.45Å; R616-D654 WeakPolarHBondContact CA-O 3.4Å; H617-D654 HydrophobicContact CB-CB 3.93Å; H617-D654 VanDerWaalsContact CB-CG 3.43Å; H617-D654 VanDerWaalsContact CB-OD1 3.27Å; H617-D654 WeakPolarHBondContact CB-OD1 3.44Å; H617-D654 IonicContact CG-OD1 2.67Å; H617-D654 IonicContact CG-OD2 3.88Å; H617-D654 PolarHBondContact N-O 2.77Å; H617-D654 IonicContact ND1-OD2 2.86Å
655L98.9Very high98.3Very high0 Ų031 Ų310%015%0.153CC..EExtended strand (participates in β ladder)trans-113.4137.6-170.2-59.2-171.1000112.2L509 N516 F518 F568 V614 I650 Q653L509-L655 PolarHBondContact N-O 3.3Å; N516-L655 HydrophobicContact CB-CD1 4.38Å; N516-L655 HydrophobicContact CB-CG 4.4Å; F518-L655 HydrophobicContact CB-CD1 4.16Å; F568-L655 HydrophobicContact CD1-CB 4.41Å; F568-L655 HydrophobicContact CD1-CD1 4.19Å; F568-L655 HydrophobicContact CE1-CB 4.25Å; F568-L655 HydrophobicContact CE1-CD1 4.28Å; V614-L655 HydrophobicContact CG1-CB 4.25Å; V614-L655 HydrophobicContact CG1-CD1 4.19Å; I650-L655 HydrophobicContact CB-CD1 4.5Å; I650-L655 HydrophobicContact CB-CD2 3.62Å; I650-L655 HydrophobicContact CG2-CD2 3.95Å; Q653-L655 HydrophobicContact CB-CD2 3.93Å; Q653-L655 WeakPolarHBondContact O-CG 3.2Å; Q653-L655 PolarHBondContact O-N 3.08Å
656V98.9Very high98.4Very high2 Ų228.1 Ų28.11%0.01215%0.15CC..EExtended strand (participates in β ladder)trans-115.4126.3172.1-175.70000108.8K506 D508 V614 T615 H617 W658K506-V656 HydrophobicContact CD-CG1 4.4Å; K506-V656 HydrophobicContact CG-CG1 3.57Å; D508-V656 HydrophobicContact CB-CG1 4.5Å; D508-V656 HydrophobicContact CB-CG2 4.21Å; V614-V656 WeakPolarHBondContact CA-O 3.48Å; T615-V656 PolarHBondContact N-O 2.95Å; T615-V656 PolarHBondContact O-N 2.94Å; H617-V656 HydrophobicContact CB-CG2 3.85Å; V656-W658 HydrophobicContact CG1-CD2 4.19Å; V656-W658 HydrophobicContact CG1-CZ2 3.94Å
657A98.9Very high98.6Very high0 Ų025.1 Ų25.10%013%0.134CC..EExtended strand (participates in β ladder)trans-90138.816700000109.7V507 F568 I585 L612V507-A657 WeakPolarHBondContact CA-O 3.45Å; V507-A657 HydrophobicContact CB-CB 4.15Å; V507-A657 PolarHBondContact N-O 2.83Å; V507-A657 PolarHBondContact O-N 2.96Å; F568-A657 HydrophobicContact CE1-CB 4.2Å; F568-A657 HydrophobicContact CE2-CB 3.97Å; F568-A657 HydrophobicContact CZ-CB 3.44Å; F568-A657 VanDerWaalsContact CZ-CB 3.44Å; I585-A657 HydrophobicContact CD1-CB 3.6Å; L612-A657 HydrophobicContact CD1-CB 4.17Å
658W98.9Very high98.6Very high2 Ų226.3 Ų26.31%0.00814%0.138CC..EExtended strand (participates in β ladder)trans-118.2117.3176.4-5992.3000107.7Q342 H504 Y505 K506 L612 A613 T615 F640 Y643 V656Q342-W658 HydrophobicContact CG-CZ3 4.18Å; H504-W658 AromaticContact CE1-CE3 3.62Å; Y505-W658 WeakPolarHBondContact O-CA 3.4Å; K506-W658 HydrophobicContact CB-CE3 3.92Å; K506-W658 HydrophobicContact CB-CH2 4.34Å; K506-W658 HydrophobicContact CB-CZ3 3.69Å; K506-W658 HydrophobicContact CD-CH2 3.98Å; K506-W658 HydrophobicContact CD-CZ3 4.15Å; K506-W658 HydrophobicContact CG-CE3 4.17Å; K506-W658 HydrophobicContact CG-CH2 3.96Å; K506-W658 HydrophobicContact CG-CZ2 4.43Å; K506-W658 HydrophobicContact CG-CZ3 3.82Å; L612-W658 VanDerWaalsContact CA-O 3.3Å; L612-W658 WeakPolarHBondContact CA-O 3.47Å; A613-W658 PolarHBondContact N-O 2.77Å; A613-W658 PolarHBondContact O-N 2.99Å; T615-W658 PolarHBondContact OG1-NE1 3.26Å; F640-W658 HydrophobicContact CD2-CD2 4.41Å; F640-W658 HydrophobicContact CE2-CB 3.86Å; F640-W658 AromaticContact CE2-CD1 3.72Å; F640-W658 AromaticContact CE2-CD2 3.45Å; F640-W658 HydrophobicContact CE2-CD2 3.45Å; F640-W658 VanDerWaalsContact CE2-CD2 3.45Å; F640-W658 AromaticContact CE2-CE2 3.76Å; F640-W658 AromaticContact CE2-CE3 3.96Å; F640-W658 HydrophobicContact CE2-CE3 3.96Å; F640-W658 AromaticContact CE2-CG 3.4Å; F640-W658 HydrophobicContact CE2-CG 3.4Å; F640-W658 HydrophobicContact CE2-CZ2 4.46Å; F640-W658 AromaticContact CE2-NE1 3.91Å; F640-W658 HydrophobicContact CZ-CB 3.55Å; F640-W658 AromaticContact CZ-CD1 3.76Å; F640-W658 HydrophobicContact CZ-CD2 4.09Å; F640-W658 AromaticContact CZ-CG 3.52Å; F640-W658 HydrophobicContact CZ-CG 3.52Å; Y643-W658 HydrophobicContact CD2-CZ2 4.06Å; Y643-W658 HydrophobicContact CE2-CH2 4.18Å; Y643-W658 HydrophobicContact CE2-CZ2 4.12Å; V656-W658 HydrophobicContact CG1-CD2 4.19Å; V656-W658 HydrophobicContact CG1-CZ2 3.94Å
659V98.9Very high98.6Very high0 Ų028.3 Ų28.30%016%0.155CC..EExtended strand (participates in β ladder)trans-116.5120.2-166.6179.30000109.4H504 Y505 V507 I585 F587 L612 V661 F684H504-V659 WeakPolarHBondContact CA-O 3.25Å; H504-V659 PolarHBondContact CD2-O 3.05Å; Y505-V659 PolarHBondContact N-O 2.9Å; Y505-V659 PolarHBondContact O-N 3.13Å; V507-V659 HydrophobicContact CG2-CB 4.42Å; V507-V659 HydrophobicContact CG2-CG2 3.77Å; I585-V659 HydrophobicContact CD1-CG2 4.16Å; I585-V659 HydrophobicContact CG2-CG2 4.34Å; F587-V659 HydrophobicContact CD1-CG1 4.41Å; F587-V659 HydrophobicContact CE1-CG1 3.58Å; F587-V659 HydrophobicContact CZ-CG1 3.77Å; F587-V659 HydrophobicContact CZ-CG2 4.48Å; L612-V659 HydrophobicContact CD1-CG2 3.76Å; V659-V661 HydrophobicContact CG1-CG1 4.06Å; V659-F684 HydrophobicContact CB-CD1 4.23Å; V659-F684 HydrophobicContact CB-CE1 4.14Å; V659-F684 HydrophobicContact CG1-CB 4.4Å; V659-F684 HydrophobicContact CG1-CD1 3.51Å; V659-F684 HydrophobicContact CG1-CE1 3.92Å; V659-F684 HydrophobicContact CG1-CG 3.99Å
660T98.9Very high98.6Very high0 Ų030.8 Ų30.80%016%0.164CC..EExtended strand (participates in β ladder)trans-103.4126.2171.5-530000110L502 I503 H504 F558 W607 Y610 P611L502-T660 HydrophobicContact CB-CG2 4.17Å; L502-T660 HydrophobicContact CD2-CG2 4.24Å; I503-T660 WeakPolarHBondContact O-CA 3.33Å; H504-T660 PolarHBondContact CD2-OG1 3.1Å; F558-T660 HydrophobicContact CE2-CG2 4.19Å; F558-T660 HydrophobicContact CZ-CG2 4.2Å; W607-T660 HydrophobicContact CE3-CG2 4.18Å; W607-T660 HydrophobicContact CZ3-CG2 3.98Å; W607-T660 PolarHBondContact O-OG1 3.33Å; Y610-T660 WeakPolarHBondContact O-CB 3.4Å; Y610-T660 PolarHBondContact O-OG1 3.42Å; P611-T660 PolarHBondContact O-N 3.15Å
661V98.8Very high98.6Very high0 Ų031 Ų310%017%0.165CC..EExtended strand (participates in β ladder)trans-126169.7172.1-60.10000109.6L502 I503 Y505 F587 S589 V659 V682 G683 F684L502-V661 CarbonylContact C-O 3.58Å; L502-V661 WeakPolarHBondContact CA-O 3.36Å; I503-V661 HydrophobicContact CB-CG2 4.1Å; I503-V661 PolarHBondContact N-O 3.49Å; I503-V661 PolarHBondContact O-N 2.77Å; Y505-V661 HydrophobicContact CD2-CG2 4.39Å; Y505-V661 HydrophobicContact CE2-CG2 3.97Å; F587-V661 HydrophobicContact CD1-CG1 4.36Å; S589-V661 WeakPolarHBondContact OG-CA 3.45Å; V659-V661 HydrophobicContact CG1-CG1 4.06Å; V661-V682 HydrophobicContact CB-CB 4.38Å; V661-V682 HydrophobicContact CB-CG2 4.34Å; V661-V682 HydrophobicContact CG2-CG2 4.07Å; V661-G683 WeakPolarHBondContact CG1-O 3.35Å; V661-F684 HydrophobicContact CG1-CD1 4.43Å
662G98.3Very high98.6Very high0 Ų030.5 Ų30.50%016%0.161CC..EExtended strand (participates in β ladder)trans153.5-176.8-171.700000113.3H501 S589 H590 A591H501-G662 CarbonylContact O-C 3.35Å; H501-G662 WeakPolarHBondContact O-CA 3.46Å; S589-G662 PolarHBondContact OG-N 2.83Å; S589-G662 VanDerWaalsContact OG-N 3.07Å; S589-G662 PolarHBondContact OG-O 3.32Å; H590-G662 CarbonylContact C-O 3.57Å; H590-G662 VanDerWaalsContact C-O 3.29Å; H590-G662 PolarHBondContact N-O 2.85Å; A591-G662 PolarHBondContact N-O 2.97Å
663F98.2Very high98.5Very high13 Ų1329 Ų296%0.05715%0.154CC..EExtended strand (participates in β ladder)trans-162156-179.458.3-84.9000111.1A470 H501 H590 H665 N680 V682A470-F663 HydrophobicContact CB-CZ 4.06Å; H501-F663 HydrophobicContact CB-CD1 4.41Å; H501-F663 HydrophobicContact CB-CE1 4.13Å; H501-F663 HydrophobicContact CB-CZ 4.28Å; H501-F663 AromaticContact CD2-CE2 3.58Å; H501-F663 AromaticContact CD2-CZ 3.52Å; H501-F663 PolarHBondContact N-O 2.92Å; H501-F663 PolarHBondContact O-N 2.89Å; H590-F663 HydrophobicContact CB-CB 4.07Å; F663-H665 HydrophobicContact CD2-CB 4.31Å; F663-H665 HydrophobicContact CE2-CB 4.07Å; F663-N680 HydrophobicContact CZ-CB 4.24Å; F663-V682 HydrophobicContact CB-CG1 4.49Å; F663-V682 HydrophobicContact CD1-CG1 3.75Å; F663-V682 HydrophobicContact CD1-CG2 4.07Å; F663-V682 HydrophobicContact CE1-CG2 4.34Å
664L98.3Very high98.5Very high103 Ų10327.6 Ų27.654%0.53915%0.148SC..EExtended strand (participates in β ladder)trans-80132.8167.4-178.770.4000108.9L498 T500 V666L498-L664 HydrophobicContact CD1-CD1 3.71Å; L498-L664 HydrophobicContact CD1-CG 4.19Å; L498-L664 HydrophobicContact CG-CD1 4.44Å; T500-L664 WeakPolarHBondContact OG1-CD1 3.31Å; L664-V666 HydrophobicContact CD2-CG2 4.34Å; L664-V666 HydrophobicContact CG-CG2 4.48Å
665H98.5Very high98.5Very high9 Ų926.5 Ų26.54%0.04214%0.142CC..EExtended strand (participates in β ladder)trans-117.6111.3173.3-170.5-169.5000108.8H499 F663 P667 D671 T675H499-H665 AromaticContact CE1-CG 3.68Å; H499-H665 AromaticContact CE1-ND1 3.25Å; H499-H665 PolarHBondContact CE1-ND1 3.35Å; H499-H665 VanDerWaalsContact CE1-ND1 3.25Å; H499-H665 PolarHBondContact N-O 3.47Å; H499-H665 AromaticContact NE2-CG 3.76Å; H499-H665 AromaticContact NE2-ND1 3.22Å; H499-H665 PolarHBondContact NE2-ND1 2.93Å; H499-H665 PolarHBondContact O-N 3.11Å; H499-H665 VanDerWaalsContact O-O 3.09Å; F663-H665 HydrophobicContact CD2-CB 4.31Å; F663-H665 HydrophobicContact CE2-CB 4.07Å; H665-P667 WeakPolarHBondContact O-CD 3.29Å; H665-D671 IonicContact CD2-OD2 3.46Å; H665-D671 IonicContact CE1-OD1 2.66Å; H665-D671 IonicContact CE1-OD2 3.47Å; H665-D671 IonicContact NE2-OD1 2.71Å; H665-D671 PolarHBondContact NE2-OD1 2.79Å; H665-D671 IonicContact NE2-OD2 3.59Å; H665-D671 PolarHBondContact NE2-OD2 3.06Å; H665-T675 PolarHBondContact CE1-OG1 3.11Å; H665-T675 VanDerWaalsContact CE1-OG1 3.26Å
666V98.4Very high98.5Very high71 Ų7129 Ų2943%0.4316%0.163SC..  trans-97103.4164.1-177.10000104.5L498 L664L498-V666 HydrophobicContact CD1-CB 4.27Å; L498-V666 HydrophobicContact CD1-CG2 3.51Å; L664-V666 HydrophobicContact CD2-CG2 4.34Å; L664-V666 HydrophobicContact CG-CG2 4.48Å
667P98.6Very high98.4Very high0 Ų031.5 Ų31.50%018%0.178CC..  trans-57.7150.4-177.9-28.437.7000111.8I474 T488 N497 H665 D671I474-P667 HydrophobicContact CD1-CB 3.94Å; I474-P667 HydrophobicContact CD1-CG 4.48Å; I474-P667 HydrophobicContact CG2-CB 4.38Å; I474-P667 HydrophobicContact CG2-CG 4.46Å; T488-P667 WeakPolarHBondContact CB-O 3.49Å; T488-P667 PolarHBondContact OG1-O 3.12Å; N497-P667 VanDerWaalsContact O-CD 3.24Å; N497-P667 WeakPolarHBondContact O-CD 3.21Å; N497-P667 VanDerWaalsContact O-CG 3.28Å; N497-P667 WeakPolarHBondContact O-CG 3.4Å; H665-P667 WeakPolarHBondContact O-CD 3.29Å; P667-D671 VanDerWaalsContact CA-OD2 3.24Å; P667-D671 WeakPolarHBondContact CA-OD2 3.44Å
668H98.6Very high98.4Very high80 Ų8036.7 Ų36.737%0.3721%0.212SC..  trans-139.9174.4178.552.385000110.8E670 D671H668-E670 IonicContact CE1-OE2 3.17Å; H668-E670 IonicContact CG-OE2 2.83Å; H668-E670 IonicContact ND1-OE2 2.77Å; H668-E670 PolarHBondContact ND1-OE2 3.41Å; H668-E670 PolarHBondContact O-N 2.8Å; H668-E670 VanDerWaalsContact O-N 3.15Å; H668-D671 IonicContact CD2-OD2 3.45Å; H668-D671 IonicContact CG-OD2 3.7Å; H668-D671 PolarHBondContact N-OD2 3.1Å; H668-D671 IonicContact NE2-OD2 3.48Å; H668-D671 VanDerWaalsContact O-CB 3.31Å; H668-D671 WeakPolarHBondContact O-CB 3.32Å; H668-D671 PolarHBondContact O-N 2.93Å
669S98.3Very high98.2Very high70 Ų7039.9 Ų39.949%0.4925%0.245SC..G310 helixtrans-57.2-31.4-173.635.20000114.1D671 I672S669-D671 PolarHBondContact O-N 2.85Å; S669-I672 WeakPolarHBondContact O-CB 3.37Å; S669-I672 PolarHBondContact O-N 3.08Å; S669-I672 VanDerWaalsContact O-N 3.15Å
670E98.4Very high98.1Very high132 Ų13241.4 Ų41.462%0.61725%0.254SS*.G310 helixtrans-76.1-7.3178.8-58.278.3178.700113.2H668 I672H668-E670 IonicContact CE1-OE2 3.17Å; H668-E670 IonicContact CG-OE2 2.83Å; H668-E670 IonicContact ND1-OE2 2.77Å; H668-E670 PolarHBondContact ND1-OE2 3.41Å; H668-E670 PolarHBondContact O-N 2.8Å; H668-E670 VanDerWaalsContact O-N 3.15Å; E670-I672 PolarHBondContact O-N 3.4Å
671D98.5Very high98Very high3 Ų342.7 Ų42.72%0.01626%0.264CS..G310 helixtrans-77.43.9165.4-69.4-56.7000112.2I474 H665 P667 H668 S669 P673 N674 T675I474-D671 HydrophobicContact CG2-CB 4Å; H665-D671 IonicContact CD2-OD2 3.46Å; H665-D671 IonicContact CE1-OD1 2.66Å; H665-D671 IonicContact CE1-OD2 3.47Å; H665-D671 IonicContact NE2-OD1 2.71Å; H665-D671 PolarHBondContact NE2-OD1 2.79Å; H665-D671 IonicContact NE2-OD2 3.59Å; H665-D671 PolarHBondContact NE2-OD2 3.06Å; P667-D671 VanDerWaalsContact CA-OD2 3.24Å; P667-D671 WeakPolarHBondContact CA-OD2 3.44Å; H668-D671 IonicContact CD2-OD2 3.45Å; H668-D671 IonicContact CG-OD2 3.7Å; H668-D671 PolarHBondContact N-OD2 3.1Å; H668-D671 IonicContact NE2-OD2 3.48Å; H668-D671 VanDerWaalsContact O-CB 3.31Å; H668-D671 WeakPolarHBondContact O-CB 3.32Å; H668-D671 PolarHBondContact O-N 2.93Å; S669-D671 PolarHBondContact O-N 2.85Å; D671-P673 CarbonylContact O-C 3.5Å; D671-N674 CarbonylContact C-O 3.56Å; D671-N674 CarbonylContact O-C 3.47Å; D671-N674 WeakPolarHBondContact O-CA 3.48Å; D671-N674 PolarHBondContact O-N 3.3Å; D671-T675 VanDerWaalsContact OD1-CA 3.25Å; D671-T675 WeakPolarHBondContact OD1-CA 3.44Å; D671-T675 VanDerWaalsContact OD1-CB 3.31Å; D671-T675 WeakPolarHBondContact OD1-CB 3.5Å; D671-T675 WeakPolarHBondContact OD1-CG2 3.45Å; D671-T675 PolarHBondContact OD1-OG1 3.39Å
672I98Very high98Very high28 Ų2842.8 Ų42.814%0.14427%0.265CS..SBendtrans-103.9123.6175.6-55.1-59000110I211 Y271 V490 S669 E670I211-I672 HydrophobicContact CD1-CD1 3.91Å; Y271-I672 HydrophobicContact CD2-CG2 3.78Å; Y271-I672 VanDerWaalsContact O-CG2 3.28Å; Y271-I672 WeakPolarHBondContact O-CG2 3.39Å; V490-I672 HydrophobicContact CB-CD1 4.17Å; V490-I672 HydrophobicContact CB-CG1 4.06Å; V490-I672 HydrophobicContact CG2-CD1 3.93Å; V490-I672 HydrophobicContact CG2-CG1 4.36Å; S669-I672 WeakPolarHBondContact O-CB 3.37Å; S669-I672 PolarHBondContact O-N 3.08Å; S669-I672 VanDerWaalsContact O-N 3.15Å; E670-I672 PolarHBondContact O-N 3.4Å
673P97.2Very high98Very high27 Ų2742.9 Ų42.918%0.17527%0.266CS..SBendcis-74.8-29.13.630.8-36.1000113.4S272 Y473 D671S272-P673 WeakPolarHBondContact O-CB 3.42Å; Y473-P673 VanDerWaalsContact CD1-O 3.25Å; Y473-P673 WeakPolarHBondContact CD1-O 3.46Å; Y473-P673 HydrophobicContact CE1-CB 4.22Å; Y473-P673 WeakPolarHBondContact CE1-O 3.28Å; D671-P673 CarbonylContact O-C 3.5Å
674N98.4Very high98.1Very high17 Ų1742.3 Ų42.39%0.09126%0.263CS..  trans-135.8151.1-172.1-84.9-161.3000112.8Y274 G472 Y473 D671 A676Y274-N674 WeakPolarHBondContact CE2-OD1 3.46Å; Y274-N674 VanDerWaalsContact CZ-OD1 3.3Å; Y274-N674 PolarHBondContact OH-OD1 2.76Å; G472-N674 VanDerWaalsContact C-OD1 3.25Å; G472-N674 WeakPolarHBondContact CA-OD1 3.29Å; G472-N674 CarbonylContact O-C 3.54Å; G472-N674 VanDerWaalsContact O-CA 3.25Å; G472-N674 WeakPolarHBondContact O-CA 3.29Å; G472-N674 WeakPolarHBondContact O-CB 3.42Å; G472-N674 PolarHBondContact O-ND2 2.84Å; Y473-N674 WeakPolarHBondContact CD1-ND2 3.31Å; Y473-N674 WeakPolarHBondContact CD2-ND2 3.02Å; Y473-N674 WeakPolarHBondContact CE1-ND2 3.38Å; Y473-N674 VanDerWaalsContact CE2-ND2 3.33Å; Y473-N674 WeakPolarHBondContact CE2-ND2 3.43Å; Y473-N674 VanDerWaalsContact CZ-ND2 3.31Å; Y473-N674 PolarHBondContact N-ND2 3.32Å; D671-N674 CarbonylContact C-O 3.56Å; D671-N674 CarbonylContact O-C 3.47Å; D671-N674 WeakPolarHBondContact O-CA 3.48Å; D671-N674 PolarHBondContact O-N 3.3Å; N674-A676 PolarHBondContact O-N 2.98Å
675T98.4Very high98.1Very high0 Ų039.4 Ų39.40%025%0.246CC..BIsolated β-bridgetrans-62.5130.1168.6-66.20000110T471 G472 I474 H665 D671 N680T471-T675 VanDerWaalsContact CA-O 3.23Å; T471-T675 WeakPolarHBondContact CA-O 3.47Å; T471-T675 VanDerWaalsContact CB-O 3.29Å; T471-T675 WeakPolarHBondContact CB-O 3.45Å; T471-T675 PolarHBondContact OG1-O 3.27Å; G472-T675 PolarHBondContact O-N 3.14Å; I474-T675 WeakPolarHBondContact CG2-OG1 3.29Å; H665-T675 PolarHBondContact CE1-OG1 3.11Å; H665-T675 VanDerWaalsContact CE1-OG1 3.26Å; D671-T675 VanDerWaalsContact OD1-CA 3.25Å; D671-T675 WeakPolarHBondContact OD1-CA 3.44Å; D671-T675 VanDerWaalsContact OD1-CB 3.31Å; D671-T675 WeakPolarHBondContact OD1-CB 3.5Å; D671-T675 WeakPolarHBondContact OD1-CG2 3.45Å; D671-T675 PolarHBondContact OD1-OG1 3.39Å; T675-N680 WeakPolarHBondContact CG2-ND2 3.12Å
676A98.3Very high98.1Very high53 Ų5339 Ų3944%0.43825%0.245SC..  trans-91.1150-179.900000111.9N674 P678 N680N674-A676 PolarHBondContact O-N 2.98Å; A676-P678 VanDerWaalsContact C-CD 3.43Å; A676-N680 PolarHBondContact O-ND2 3.26Å
677T98.4Very high98.1Very high53 Ų5340 Ų4033%0.32524%0.241SC..SBendtrans-69.6-29.2179.460.40000116.1I453 T471 G679 N680I453-T677 HydrophobicContact CD1-CG2 4.07Å; T471-T677 HydrophobicContact CG2-CG2 4.31Å; T677-G679 PolarHBondContact O-N 2.98Å; T677-N680 PolarHBondContact O-N 3.01Å
678P98Very high98.1Very high109 Ų10941.7 Ų41.771%0.70825%0.251SS*.THydrogen-bonded Turntrans-60.1121179.8-25.336.4000112.2A676 N680A676-P678 VanDerWaalsContact C-CD 3.43Å; P678-N680 PolarHBondContact O-N 3.1Å
679G95.2Very high98.1Very high69 Ų6940.1 Ų40.171%0.71124%0.243SC*.THydrogen-bonded Turntrans85.4-17.8-177.300000114.9T677 A681T677-G679 PolarHBondContact O-N 2.98Å; G679-A681 VanDerWaalsContact C-N 3.35Å; G679-A681 PolarHBondContact O-N 2.93Å
680N96.6Very high98.1Very high33 Ų3339.2 Ų39.218%0.17623%0.233CC..  trans-97.826.4179.6-70.1-35000113.2A470 F663 T675 A676 T677 P678A470-N680 PolarHBondContact N-O 3.32Å; F663-N680 HydrophobicContact CZ-CB 4.24Å; T675-N680 WeakPolarHBondContact CG2-ND2 3.12Å; A676-N680 PolarHBondContact O-ND2 3.26Å; T677-N680 PolarHBondContact O-N 3.01Å; P678-N680 PolarHBondContact O-N 3.1Å
681A97.2Very high98.1Very high27 Ų2733 Ų3322%0.22320%0.204CC..EExtended strand (participates in β ladder)trans-104.8122.7175.900000111.2K467 V468 S469 N588 G679K467-A681 HydrophobicContact CD-CB 4.2Å; K467-A681 HydrophobicContact CG-CB 4.24Å; V468-A681 CarbonylContact O-C 3.53Å; V468-A681 VanDerWaalsContact O-CA 3.27Å; V468-A681 WeakPolarHBondContact O-CA 3.37Å; S469-A681 WeakPolarHBondContact OG-CB 3.41Å; N588-A681 PolarHBondContact ND2-O 3.3Å; G679-A681 VanDerWaalsContact C-N 3.35Å; G679-A681 PolarHBondContact O-N 2.93Å
682V98.6Very high98.1Very high1 Ų134.6 Ų34.61%0.00621%0.211CC..EExtended strand (participates in β ladder)trans-129.4161.8178.4-64.60000110.7K467 V468 I503 N588 V661 F663K467-V682 WeakPolarHBondContact CA-O 3.45Å; V468-V682 HydrophobicContact CG1-CG2 3.58Å; V468-V682 WeakPolarHBondContact CG1-O 3.49Å; V468-V682 PolarHBondContact N-O 3.09Å; V468-V682 PolarHBondContact O-N 3.36Å; I503-V682 HydrophobicContact CD1-CG2 4.4Å; N588-V682 CarbonylContact O-C 3.54Å; N588-V682 VanDerWaalsContact O-CA 3.3Å; N588-V682 WeakPolarHBondContact O-CA 3.12Å; N588-V682 WeakPolarHBondContact O-CB 3.3Å; V661-V682 HydrophobicContact CB-CB 4.38Å; V661-V682 HydrophobicContact CB-CG2 4.34Å; V661-V682 HydrophobicContact CG2-CG2 4.07Å; F663-V682 HydrophobicContact CB-CG1 4.49Å; F663-V682 HydrophobicContact CD1-CG1 3.75Å; F663-V682 HydrophobicContact CD1-CG2 4.07Å; F663-V682 HydrophobicContact CE1-CG2 4.34Å
683G98.6Very high98.2Very high2 Ų237 Ų372%0.02122%0.224CC..EExtended strand (participates in β ladder)trans161.9-158.6-170.900000113.7V466 N588 V661V466-G683 CarbonylContact O-C 3.37Å; V466-G683 WeakPolarHBondContact O-CA 3.2Å; N588-G683 CarbonylContact C-O 3.49Å; N588-G683 WeakPolarHBondContact CA-O 3.06Å; N588-G683 PolarHBondContact N-O 2.89Å; N588-G683 PolarHBondContact O-N 3.11Å; N588-G683 VanDerWaalsContact O-O 3.05Å; V661-G683 WeakPolarHBondContact CG1-O 3.35Å
684F98.9Very high98.2Very high1 Ų142.5 Ų42.50%0.00425%0.248CC..EExtended strand (participates in β ladder)trans-154.4161.4176.861.2-87.1000111.6I339 V466 Y505 V507 I585 Q586 V659 V661 L686I339-F684 HydrophobicContact CG2-CZ 4.24Å; V466-F684 HydrophobicContact CB-CD1 4.14Å; V466-F684 HydrophobicContact CB-CD2 4.46Å; V466-F684 HydrophobicContact CB-CE1 3.72Å; V466-F684 HydrophobicContact CB-CE2 4.07Å; V466-F684 HydrophobicContact CB-CG 4.49Å; V466-F684 HydrophobicContact CB-CZ 3.68Å; V466-F684 HydrophobicContact CG1-CE1 3.9Å; V466-F684 HydrophobicContact CG1-CZ 4.06Å; V466-F684 HydrophobicContact CG2-CD2 4.3Å; V466-F684 HydrophobicContact CG2-CE1 4.06Å; V466-F684 HydrophobicContact CG2-CE2 3.6Å; V466-F684 HydrophobicContact CG2-CZ 3.47Å; V466-F684 VanDerWaalsContact CG2-CZ 3.47Å; V466-F684 PolarHBondContact N-O 3.48Å; V466-F684 PolarHBondContact O-N 2.9Å; Y505-F684 HydrophobicContact CD1-CE1 4.38Å; Y505-F684 AromaticContact CD2-CE1 3.78Å; Y505-F684 HydrophobicContact CD2-CE1 3.78Å; Y505-F684 HydrophobicContact CE2-CE1 4.41Å; Y505-F684 AromaticContact CG-CE1 3.75Å; Y505-F684 HydrophobicContact CG-CE1 3.75Å; Y505-F684 HydrophobicContact CG-CZ 4.34Å; V507-F684 HydrophobicContact CG2-CE1 4.46Å; V507-F684 HydrophobicContact CG2-CE2 3.83Å; V507-F684 HydrophobicContact CG2-CZ 3.54Å; I585-F684 HydrophobicContact CG2-CB 4.2Å; I585-F684 HydrophobicContact CG2-CD2 4.08Å; I585-F684 HydrophobicContact CG2-CG 4.37Å; Q586-F684 CarbonylContact O-C 3.59Å; Q586-F684 WeakPolarHBondContact O-CA 3.37Å; Q586-F684 WeakPolarHBondContact O-CB 3.44Å; V659-F684 HydrophobicContact CB-CD1 4.23Å; V659-F684 HydrophobicContact CB-CE1 4.14Å; V659-F684 HydrophobicContact CG1-CB 4.4Å; V659-F684 HydrophobicContact CG1-CD1 3.51Å; V659-F684 HydrophobicContact CG1-CE1 3.92Å; V659-F684 HydrophobicContact CG1-CG 3.99Å; V661-F684 HydrophobicContact CG1-CD1 4.43Å; F684-L686 HydrophobicContact CD2-CD2 4.2Å; F684-L686 HydrophobicContact CD2-CG 4.48Å; F684-L686 HydrophobicContact CE2-CD2 4.1Å; F684-L686 HydrophobicContact CE2-CG 4.24Å
685F98.9Very high98.2Very high42 Ų4244.4 Ų44.418%0.18426%0.258CS..EExtended strand (participates in β ladder)trans-111.9137.4174.5-61.2-99000110.4Y459 V463 V464 E465 I585 Q586 R687Y459-F685 HydrophobicContact CE2-CE1 4.44Å; V463-F685 HydrophobicContact CG1-CB 4.43Å; V463-F685 HydrophobicContact CG1-CD1 3.89Å; V464-F685 CarbonylContact O-C 3.56Å; V464-F685 VanDerWaalsContact O-CA 3.25Å; V464-F685 WeakPolarHBondContact O-CA 3.25Å; E465-F685 HydrophobicContact CB-CD1 3.61Å; E465-F685 HydrophobicContact CB-CE1 3.55Å; E465-F685 HydrophobicContact CB-CG 4.45Å; E465-F685 HydrophobicContact CB-CZ 4.31Å; E465-F685 HydrophobicContact CG-CD1 3.84Å; E465-F685 HydrophobicContact CG-CE1 3.42Å; E465-F685 VanDerWaalsContact CG-CE1 3.42Å; E465-F685 HydrophobicContact CG-CE2 4.3Å; E465-F685 HydrophobicContact CG-CG 4.44Å; E465-F685 HydrophobicContact CG-CZ 3.67Å; E465-F685 VanDerWaalsContact OE2-CE1 3.27Å; E465-F685 WeakPolarHBondContact OE2-CE1 3.02Å; I585-F685 CarbonylContact C-O 3.45Å; I585-F685 WeakPolarHBondContact CA-O 3.25Å; Q586-F685 HydrophobicContact CB-CB 4.31Å; Q586-F685 PolarHBondContact N-O 3.2Å; Q586-F685 PolarHBondContact O-N 3.37Å; F685-R687 HydrophobicContact CB-CG 3.86Å
686L98.8Very high98.2Very high1 Ų145.5 Ų45.51%0.00527%0.265CS..EExtended strand (participates in β ladder)trans-95.2115159.9-59.2-174.8000108.3I339 V463 V464 V507 L509 Y583 R584 I585 F684I339-L686 HydrophobicContact CD1-CD1 3.49Å; I339-L686 VanDerWaalsContact CD1-CD1 3.49Å; I339-L686 HydrophobicContact CG1-CD1 4.45Å; V463-L686 WeakPolarHBondContact CA-O 3.24Å; V464-L686 HydrophobicContact CB-CB 4.4Å; V464-L686 PolarHBondContact N-O 3.43Å; V464-L686 PolarHBondContact O-N 3.34Å; V507-L686 HydrophobicContact CG1-CD1 3.98Å; V507-L686 HydrophobicContact CG1-CD2 4.06Å; L509-L686 HydrophobicContact CD2-CD1 3.92Å; L509-L686 HydrophobicContact CD2-CD2 4.46Å; Y583-L686 HydrophobicContact CD1-CB 4.08Å; R584-L686 WeakPolarHBondContact O-CA 3.04Å; I585-L686 HydrophobicContact CB-CD2 4.46Å; I585-L686 HydrophobicContact CD1-CD2 4.26Å; I585-L686 HydrophobicContact CG1-CD2 3.7Å; F684-L686 HydrophobicContact CD2-CD2 4.2Å; F684-L686 HydrophobicContact CD2-CG 4.48Å; F684-L686 HydrophobicContact CE2-CD2 4.1Å; F684-L686 HydrophobicContact CE2-CG 4.24Å
687R98.8Very high98.1Very high93 Ų9343 Ų4335%0.35125%0.245SC..EExtended strand (participates in β ladder)trans-119.5133.3-176.4-57.4-177.658.3174.41.4111.3V463 Y583 R584 Q586 F685 F689V463-R687 HydrophobicContact CG1-CG 4.04Å; V463-R687 HydrophobicContact CG2-CB 4.22Å; V463-R687 HydrophobicContact CG2-CG 3.98Å; Y583-R687 CarbonylContact C-O 3.48Å; Y583-R687 WeakPolarHBondContact CA-O 3.2Å; R584-R687 HydrophobicContact CG-CB 3.89Å; R584-R687 PolarHBondContact N-O 3.25Å; R584-R687 PolarHBondContact O-N 2.65Å; Q586-R687 VanDerWaalsContact OE1-CD 3.26Å; F685-R687 HydrophobicContact CB-CG 3.86Å; R687-F689 PolarHBondContact O-N 2.75Å
688P98.8Very high98.1Very high34 Ų3444.6 Ų44.622%0.22125%0.25CS..EExtended strand (participates in β ladder)trans-62.9134.7174.325.7-31.5000109.5G462 Y583 F691 F692G462-P688 WeakPolarHBondContact O-CD 3.4Å; Y583-P688 HydrophobicContact CE1-CB 4.15Å; Y583-P688 HydrophobicContact CE1-CG 4.49Å; Y583-P688 HydrophobicContact CE2-CB 3.98Å; P688-F691 HydrophobicContact CB-CB 3.9Å; P688-F692 HydrophobicContact CB-CD2 3.8Å; P688-F692 HydrophobicContact CB-CE2 3.72Å; P688-F692 HydrophobicContact CG-CD2 4.18Å; P688-F692 HydrophobicContact CG-CE2 4.01Å
689F98.5Very high98Very high47 Ų4743.5 Ų43.521%0.20625%0.251CS..EExtended strand (participates in β ladder)trans-133.2102.5176.8-173-104.1000108.7I521 Y565 H567 G582 R687 F691I521-F689 HydrophobicContact CD1-CE1 3.86Å; I521-F689 HydrophobicContact CD1-CZ 4.23Å; Y565-F689 HydrophobicContact CD1-CE2 4.36Å; Y565-F689 HydrophobicContact CE1-CD2 4.41Å; Y565-F689 AromaticContact CE1-CE2 3.94Å; Y565-F689 HydrophobicContact CE1-CE2 3.94Å; Y565-F689 HydrophobicContact CE1-CZ 4.47Å; H567-F689 AromaticContact CD2-CD1 3.78Å; H567-F689 AromaticContact CE1-CD1 3.69Å; H567-F689 AromaticContact NE2-CD1 3.45Å; H567-F689 WeakPolarHBondContact NE2-CD1 3.47Å; G582-F689 CarbonylContact C-O 3.53Å; G582-F689 PolarHBondContact N-O 3.48Å; G582-F689 CarbonylContact O-C 3.55Å; G582-F689 PolarHBondContact O-N 3.25Å; R687-F689 PolarHBondContact O-N 2.75Å; F689-F691 PolarHBondContact O-N 3Å
690N98.4Very high98Very high51 Ų5142 Ų4227%0.27323%0.229SC..BIsolated β-bridgetrans57.712.9-170.2-58.9-53.3000115N575 H579N575-N690 WeakPolarHBondContact CB-O 3.49Å; N575-N690 PolarHBondContact ND2-O 3.02Å; N575-N690 VanDerWaalsContact ND2-O 3.12Å; H579-N690 HydrophobicContact CB-CB 3.73Å
691F98.6Very high97.9Very high1 Ų147.2 Ų47.20%0.00425%0.25CS..SBendtrans-63.7-49.3175-171.2-89.8000112.4E333 I335 I511 V512 K581 G582 Y583 P688 F689E333-F691 HydrophobicContact CB-CE1 4.36Å; E333-F691 HydrophobicContact CB-CZ 4.04Å; E333-F691 WeakPolarHBondContact OE2-CZ 3.23Å; I335-F691 HydrophobicContact CG1-CZ 4.45Å; I511-F691 HydrophobicContact CG2-CD2 3.86Å; I511-F691 HydrophobicContact CG2-CE2 3.79Å; V512-F691 HydrophobicContact CG2-CD2 4.36Å; V512-F691 HydrophobicContact CG2-CE2 3.44Å; V512-F691 VanDerWaalsContact CG2-CE2 3.44Å; V512-F691 HydrophobicContact CG2-CZ 3.71Å; K581-F691 HydrophobicContact CB-CD2 4.11Å; K581-F691 WeakPolarHBondContact CD-O 3.23Å; K581-F691 VanDerWaalsContact CE-O 3.32Å; K581-F691 WeakPolarHBondContact CE-O 3.37Å; K581-F691 WeakPolarHBondContact CG-O 3.21Å; G582-F691 WeakPolarHBondContact O-CB 3.37Å; Y583-F691 HydrophobicContact CD2-CB 4.29Å; Y583-F691 AromaticContact CD2-CD2 3.66Å; Y583-F691 HydrophobicContact CD2-CD2 3.66Å; Y583-F691 HydrophobicContact CD2-CE2 4.18Å; Y583-F691 HydrophobicContact CD2-CG 4.06Å; Y583-F691 HydrophobicContact CE2-CB 4Å; Y583-F691 HydrophobicContact CE2-CD1 4.03Å; Y583-F691 AromaticContact CE2-CD2 3.51Å; Y583-F691 HydrophobicContact CE2-CD2 3.51Å; Y583-F691 HydrophobicContact CE2-CE1 4.38Å; Y583-F691 AromaticContact CE2-CE2 3.89Å; Y583-F691 HydrophobicContact CE2-CE2 3.89Å; Y583-F691 AromaticContact CE2-CG 3.57Å; Y583-F691 HydrophobicContact CE2-CG 3.57Å; Y583-F691 HydrophobicContact CE2-CZ 4.32Å; P688-F691 HydrophobicContact CB-CB 3.9Å; F689-F691 PolarHBondContact O-N 3Å
692F98.4Very high97.8Very high38 Ų3847.5 Ų47.517%0.16725%0.25CS..SBendtrans-93164.9176.8-56.4-72.6000111.1F330 P688 E694 P696F330-F692 HydrophobicContact CB-CZ 4.32Å; F330-F692 AromaticContact CD1-CE1 3.77Å; F330-F692 HydrophobicContact CD1-CE1 3.77Å; F330-F692 HydrophobicContact CD1-CE2 4.41Å; F330-F692 AromaticContact CD1-CZ 3.42Å; F330-F692 HydrophobicContact CD1-CZ 3.42Å; F330-F692 VanDerWaalsContact CD1-CZ 3.42Å; F330-F692 HydrophobicContact CE1-CE1 4.28Å; F330-F692 AromaticContact CE1-CZ 3.99Å; F330-F692 HydrophobicContact CE1-CZ 3.99Å; F330-F692 HydrophobicContact CG-CZ 4.07Å; P688-F692 HydrophobicContact CB-CD2 3.8Å; P688-F692 HydrophobicContact CB-CE2 3.72Å; P688-F692 HydrophobicContact CG-CD2 4.18Å; P688-F692 HydrophobicContact CG-CE2 4.01Å; F692-E694 VanDerWaalsContact C-N 3.32Å; F692-E694 WeakPolarHBondContact CB-O 3.5Å; F692-P696 HydrophobicContact CD1-CB 4.34Å; F692-P696 HydrophobicContact CD2-CB 4.2Å; F692-P696 HydrophobicContact CD2-CG 3.62Å; F692-P696 HydrophobicContact CE1-CB 4.42Å; F692-P696 HydrophobicContact CE2-CB 4.29Å; F692-P696 HydrophobicContact CE2-CG 3.69Å; F692-P696 HydrophobicContact CG-CB 4.23Å; F692-P696 HydrophobicContact CG-CG 4.13Å; F692-P696 HydrophobicContact CZ-CB 4.41Å; F692-P696 HydrophobicContact CZ-CG 4.23Å
693N98.3Very high97.7Very high79 Ų7948 Ų4842%0.42225%0.253SS..SBendtrans-76.2-23.6174.8-65-33.8000112.5K576 W577K576-N693 HydrophobicContact CB-CB 4.32Å; K576-N693 VanDerWaalsContact CB-OD1 3.29Å; K576-N693 WeakPolarHBondContact CB-OD1 3.39Å; K576-N693 PolarHBondContact N-OD1 3.09Å; W577-N693 PolarHBondContact NE1-O 3Å
694E98.3Very high97.7Very high142 Ų14249.1 Ų49.166%0.66426%0.26SS*.SBendtrans-160.4-179178.256.5-173.6172.400108.6F692 P696 L698F692-E694 VanDerWaalsContact C-N 3.32Å; F692-E694 WeakPolarHBondContact CB-O 3.5Å; E694-P696 WeakPolarHBondContact O-CD 3.46Å; E694-L698 HydrophobicContact CB-CD1 4.18Å; E694-L698 HydrophobicContact CG-CD1 3.85Å
695D98.4Very high97.6Very high56 Ų5650.5 Ų50.530%0.29927%0.267SS..  trans-59.5116.8177.2172.515.6000110.8R417 S697 L698R417-D695 WeakPolarHBondContact CD-OD2 3.42Å; R417-D695 IonicContact NE-OD2 3.39Å; R417-D695 PolarHBondContact NE-OD2 3.42Å; D695-S697 PolarHBondContact O-N 2.97Å; D695-S697 VanDerWaalsContact O-N 3.15Å; D695-S697 VanDerWaalsContact OD1-CB 3.27Å; D695-S697 WeakPolarHBondContact OD1-CB 3.14Å; D695-S697 PolarHBondContact OD1-N 2.86Å; D695-S697 PolarHBondContact OD1-OG 3.25Å; D695-S697 VanDerWaalsContact OD1-OG 3.13Å; D695-S697 PolarHBondContact OD2-OG 3.26Å; D695-L698 HydrophobicContact CB-CD1 4.45Å; D695-L698 HydrophobicContact CB-CG 4.32Å; D695-L698 WeakPolarHBondContact O-CB 3.43Å; D695-L698 WeakPolarHBondContact O-CD1 3.38Å; D695-L698 VanDerWaalsContact O-CG 3.24Å; D695-L698 WeakPolarHBondContact O-CG 3.45Å; D695-L698 PolarHBondContact O-N 3.01Å; D695-L698 VanDerWaalsContact O-N 3.15Å
696P97.9Very high97.6Very high23 Ų2349.8 Ų49.815%0.14927%0.266CS..G310 helixtrans-66.5-16.7-17928.5-36000113.1F330 N461 F692 E694 L698 A699F330-P696 HydrophobicContact CE1-CB 3.56Å; F330-P696 HydrophobicContact CE1-CG 4.07Å; F330-P696 HydrophobicContact CZ-CB 3.99Å; F330-P696 HydrophobicContact CZ-CG 4.25Å; N461-P696 VanDerWaalsContact C-CG 3.46Å; N461-P696 WeakPolarHBondContact O-CG 3.46Å; F692-P696 HydrophobicContact CD1-CB 4.34Å; F692-P696 HydrophobicContact CD2-CB 4.2Å; F692-P696 HydrophobicContact CD2-CG 3.62Å; F692-P696 HydrophobicContact CE1-CB 4.42Å; F692-P696 HydrophobicContact CE2-CB 4.29Å; F692-P696 HydrophobicContact CE2-CG 3.69Å; F692-P696 HydrophobicContact CG-CB 4.23Å; F692-P696 HydrophobicContact CG-CG 4.13Å; F692-P696 HydrophobicContact CZ-CB 4.41Å; F692-P696 HydrophobicContact CZ-CG 4.23Å; E694-P696 WeakPolarHBondContact O-CD 3.46Å; P696-L698 PolarHBondContact O-N 3.36Å; P696-L698 VanDerWaalsContact O-N 3.15Å; P696-A699 PolarHBondContact O-N 3.26Å
697S97.5Very high97.5Very high2 Ų255 Ų551%0.01429%0.286CS..G310 helixtrans-66.7-11.8175.189.80000113.4R417 D695 A699 S700R417-S697 PolarHBondContact NE-OG 2.99Å; R417-S697 VanDerWaalsContact NE-OG 3.14Å; D695-S697 PolarHBondContact O-N 2.97Å; D695-S697 VanDerWaalsContact O-N 3.15Å; D695-S697 VanDerWaalsContact OD1-CB 3.27Å; D695-S697 WeakPolarHBondContact OD1-CB 3.14Å; D695-S697 PolarHBondContact OD1-N 2.86Å; D695-S697 PolarHBondContact OD1-OG 3.25Å; D695-S697 VanDerWaalsContact OD1-OG 3.13Å; D695-S697 PolarHBondContact OD2-OG 3.26Å; S697-A699 PolarHBondContact O-N 2.73Å; S697-S700 WeakPolarHBondContact O-CB 3.16Å; S697-S700 PolarHBondContact O-N 2.73Å
698L97.3Very high97.4Very high86 Ų8653.8 Ų53.845%0.4529%0.29SS..G310 helixtrans-60.5-23.5174.3-70.4171.3000112.8E694 D695 P696 S700E694-L698 HydrophobicContact CB-CD1 4.18Å; E694-L698 HydrophobicContact CG-CD1 3.85Å; D695-L698 HydrophobicContact CB-CD1 4.45Å; D695-L698 HydrophobicContact CB-CG 4.32Å; D695-L698 WeakPolarHBondContact O-CB 3.43Å; D695-L698 WeakPolarHBondContact O-CD1 3.38Å; D695-L698 VanDerWaalsContact O-CG 3.24Å; D695-L698 WeakPolarHBondContact O-CG 3.45Å; D695-L698 PolarHBondContact O-N 3.01Å; D695-L698 VanDerWaalsContact O-N 3.15Å; P696-L698 PolarHBondContact O-N 3.36Å; P696-L698 VanDerWaalsContact O-N 3.15Å; L698-S700 PolarHBondContact O-N 3.44Å
699A95.6Very high97Very high86 Ų8653 Ų5371%0.71129%0.288SS*.G310 helixtrans-70.2-14.2173.300000113.5P696 S697 K701P696-A699 PolarHBondContact O-N 3.26Å; S697-A699 PolarHBondContact O-N 2.73Å; A699-K701 PolarHBondContact O-N 3.04Å
700S95.8Very high96.5Very high36 Ų3661.2 Ų61.225%0.25233%0.327SS..  trans-69122.9-178.4-178.40000112.5S697 L698 S702 T703S697-S700 WeakPolarHBondContact O-CB 3.16Å; S697-S700 PolarHBondContact O-N 2.73Å; L698-S700 PolarHBondContact O-N 3.44Å; S700-S702 PolarHBondContact O-N 2.8Å; S700-S702 PolarHBondContact OG-N 3.13Å; S700-T703 PolarHBondContact O-OG1 2.62Å
701K95.1Very high96Very high144 Ų14464.2 Ų64.263%0.62634%0.343SS*.THydrogen-bonded Turntrans-73.1-10.3173.4-67.2-175.3-179.1177.10113.5A699 T703 W719 T720A699-K701 PolarHBondContact O-N 3.04Å; K701-T703 PolarHBondContact O-N 3.29Å; K701-W719 HydrophobicContact CB-CB 3.74Å; K701-W719 HydrophobicContact CD-CB 4.47Å; K701-W719 HydrophobicContact CG-CB 4.05Å; K701-W719 WeakPolarHBondContact O-CB 3.48Å; K701-T720 HydrophobicContact CB-CG2 4.22Å
702S93.9Very high95.1Very high32 Ų3267.5 Ų67.522%0.22438%0.377CS..THydrogen-bonded Turntrans-77.70.2176.8-55.90000113.6S700S700-S702 PolarHBondContact O-N 2.8Å; S700-S702 PolarHBondContact OG-N 3.13Å
703T96.9Very high94.7Very high12 Ų1272.5 Ų72.57%0.07440%0.399CS..  trans-65.2135.1175.4-58.50000110.5R417 S700 K701 I705R417-T703 PolarHBondContact NH2-OG1 2.83Å; S700-T703 PolarHBondContact O-OG1 2.62Å; K701-T703 PolarHBondContact O-N 3.29Å; T703-I705 HydrophobicContact CG2-CG1 4.12Å
704V97.6Very high94.6Very high25 Ų2572.8 Ų72.815%0.15241%0.405CS..EExtended strand (participates in β ladder)trans-112.7131.1172.8-175.90000109.2G432 G433 V706 V716 R718G432-V704 WeakPolarHBondContact CA-O 3.42Å; G433-V704 PolarHBondContact N-O 2.97Å; G433-V704 PolarHBondContact O-N 3.23Å; V704-V706 HydrophobicContact CG1-CG2 4.4Å; V704-V716 HydrophobicContact CG1-CG1 3.89Å; V704-R718 HydrophobicContact CG1-CG 4.37Å; V704-R718 HydrophobicContact CG2-CG 4.31Å
705I98.1Very high94.5Very high31 Ų3173.4 Ų73.416%0.15941%0.406CS..EExtended strand (participates in β ladder)trans-124.5132.4173.6-55178.9000109.2F431 T703 R707 Q717 W719F431-I705 CarbonylContact O-C 3.38Å; F431-I705 VanDerWaalsContact O-CA 3.29Å; F431-I705 WeakPolarHBondContact O-CA 3.23Å; F431-I705 WeakPolarHBondContact O-CG2 3.31Å; T703-I705 HydrophobicContact CG2-CG1 4.12Å; I705-R707 HydrophobicContact CG2-CG 4.3Å; I705-Q717 HydrophobicContact CB-CB 4.35Å; I705-Q717 PolarHBondContact N-O 3.01Å; I705-Q717 PolarHBondContact O-N 3.02Å; I705-W719 HydrophobicContact CD1-CH2 4.11Å; I705-W719 HydrophobicContact CD1-CZ3 4.42Å
706V98.1Very high94.4Very high27 Ų2774.1 Ų74.116%0.16441%0.412CS..EExtended strand (participates in β ladder)trans-117.6129.7176.3-173.70000108.9Y428 F430 F431 V704 P714 K715 V716Y428-V706 HydrophobicContact CE2-CG1 4.21Å; F430-V706 CarbonylContact C-O 3.58Å; F430-V706 WeakPolarHBondContact CA-O 3.25Å; F430-V706 WeakPolarHBondContact CB-O 3.44Å; F431-V706 HydrophobicContact CB-CB 4.28Å; F431-V706 HydrophobicContact CD1-CG2 4.12Å; F431-V706 PolarHBondContact N-O 2.93Å; F431-V706 PolarHBondContact O-N 3.49Å; V704-V706 HydrophobicContact CG1-CG2 4.4Å; V706-P714 HydrophobicContact CG1-CB 3.66Å; V706-K715 WeakPolarHBondContact CA-O 3.42Å; V706-V716 HydrophobicContact CG2-CG1 4.41Å; V706-V716 HydrophobicContact CG2-CG2 4.25Å
707R97.9Very high94.3Very high110 Ų11076.4 Ų76.442%0.41542%0.42SS..EExtended strand (participates in β ladder)trans-126.7154.8176.2-64.2-169-176.681.6-2.5111.1F430 I705 G709 K715F430-R707 HydrophobicContact CB-CG 3.96Å; I705-R707 HydrophobicContact CG2-CG 4.3Å; R707-G709 PolarHBondContact O-N 2.88Å; R707-K715 PolarHBondContact N-O 2.85Å; R707-K715 PolarHBondContact O-N 2.9Å
708P95.6Very high94.2Very high67 Ų6781.3 Ų81.344%0.43544%0.439SS..EExtended strand (participates in β ladder)trans-58.9130.3167.3-20.531.9000111Y428 N429Y428-P708 HydrophobicContact CE1-CG 4.43Å; Y428-P708 HydrophobicContact CE2-CG 4.25Å; Y428-P708 WeakPolarHBondContact O-CG 3.41Å; N429-P708 WeakPolarHBondContact O-CD 3.37Å
709G91.4Very high94.1Very high19 Ų1983.5 Ų83.520%0.19644%0.441CS..  trans-79.6161.2167.800000111.6R707 D711 G712 K713R707-G709 PolarHBondContact O-N 2.88Å; G709-D711 PolarHBondContact O-N 2.91Å; G709-G712 PolarHBondContact O-N 2.9Å; G709-K713 WeakPolarHBondContact CA-O 3.45Å; G709-K713 PolarHBondContact N-O 3.44Å
710Q86.4Confident93.9Very high218 Ų21881.9 Ų81.9100%1.01942%0.423SS*.THydrogen-bonded Turntrans-66.6-22.2176.2-69.8-178.3-18.400112.6G712Q710-G712 VanDerWaalsContact C-N 3.32Å
711D88.6Confident93.5Very high115 Ų11583.6 Ų83.662%0.61543%0.433SS*.THydrogen-bonded Turntrans-89.26.4176.865.7-20.7000113.2G709 K713G709-D711 PolarHBondContact O-N 2.91Å; D711-K713 PolarHBondContact O-N 2.85Å; D711-K713 PolarHBondContact OD1-N 2.73Å; D711-K713 VanDerWaalsContact OD1-N 3.09Å; D711-K713 WeakPolarHBondContact OD2-CD 3.38Å
712G79.6Confident92.9Very high69 Ų6984 Ų8471%0.71144%0.437SS*.SBendtrans78.9-2.3-175.900000114.6G709 Q710G709-G712 PolarHBondContact O-N 2.9Å; Q710-G712 VanDerWaalsContact C-N 3.32Å
713K90.9Very high92.3Very high143 Ų14388 Ų8862%0.62246%0.46SS*.SBendtrans-90.4146.4177-63.9-176.9-176.4173.40111.4G709 D711 K715G709-K713 WeakPolarHBondContact CA-O 3.45Å; G709-K713 PolarHBondContact N-O 3.44Å; D711-K713 PolarHBondContact O-N 2.85Å; D711-K713 PolarHBondContact OD1-N 2.73Å; D711-K713 VanDerWaalsContact OD1-N 3.09Å; D711-K713 WeakPolarHBondContact OD2-CD 3.38Å; K713-K715 PolarHBondContact O-N 2.78Å
714P95.3Very high91.3Very high86 Ų8690.6 Ų90.656%0.55848%0.475SS*.EExtended strand (participates in β ladder)trans-63.2127.8174.1-2233.6000112.1Y428 V706Y428-P714 WeakPolarHBondContact OH-CB 3.24Å; V706-P714 HydrophobicContact CG1-CB 3.66Å
715K96Very high90.4Very high155 Ų15591.3 Ų91.367%0.67449%0.488SS*.EExtended strand (participates in β ladder)trans-95113.4169.4-175.6175.2-179.11750109.6V706 R707 K713V706-K715 WeakPolarHBondContact CA-O 3.42Å; R707-K715 PolarHBondContact N-O 2.85Å; R707-K715 PolarHBondContact O-N 2.9Å; K713-K715 PolarHBondContact O-N 2.78Å
716V96.4Very high89.1Confident71 Ų7199 Ų9943%0.4352%0.522SS..EExtended strand (participates in β ladder)trans-89.4126.4177.5-171.40000109.7V704 V706 R718V704-V716 HydrophobicContact CG1-CG1 3.89Å; V706-V716 HydrophobicContact CG2-CG1 4.41Å; V706-V716 HydrophobicContact CG2-CG2 4.25Å; V716-R718 HydrophobicContact CG1-CG 4.06Å
717Q96.7Very high88.1Confident70 Ų7099.9 Ų99.933%0.32753%0.529SS..EExtended strand (participates in β ladder)trans-109.7124.7174.5-178.2178.19.200109.1I705 W719I705-Q717 HydrophobicContact CB-CB 4.35Å; I705-Q717 PolarHBondContact N-O 3.01Å; I705-Q717 PolarHBondContact O-N 3.02Å; Q717-W719 HydrophobicContact CG-CH2 3.78Å; Q717-W719 HydrophobicContact CG-CZ2 4.13Å; Q717-W719 HydrophobicContact CG-CZ3 4.05Å
718R95.6Very high87Confident106 Ų106100.4 Ų100.440%0.455%0.545SS..  trans-136.1159.6178.6-64.1177.2177.4-94.51109.8V704 V716V704-R718 HydrophobicContact CG1-CG 4.37Å; V704-R718 HydrophobicContact CG2-CG 4.31Å; V716-R718 HydrophobicContact CG1-CG 4.06Å
719W95.5Very high86Confident131 Ų131100 Ų10050%0.49654%0.541SS..SBendtrans-120.44.1170.6-65.7-99000112.8K701 I705 Q717K701-W719 HydrophobicContact CB-CB 3.74Å; K701-W719 HydrophobicContact CD-CB 4.47Å; K701-W719 HydrophobicContact CG-CB 4.05Å; K701-W719 WeakPolarHBondContact O-CB 3.48Å; I705-W719 HydrophobicContact CD1-CH2 4.11Å; I705-W719 HydrophobicContact CD1-CZ3 4.42Å; Q717-W719 HydrophobicContact CG-CH2 3.78Å; Q717-W719 HydrophobicContact CG-CZ2 4.13Å; Q717-W719 HydrophobicContact CG-CZ3 4.05Å
720T90.4Very high85.5Confident53 Ų53106.3 Ų106.333%0.32557%0.57SS.*SBendtrans-119160.5169.652.60000109.2K701K701-T720 HydrophobicContact CB-CG2 4.22Å
721P86.9Confident85.3Confident72 Ų72103.9 Ų103.947%0.46856%0.556SS.*  trans-53.9145.8175.5-25.735.4000112.4
722E83.5Confident85.3Confident153 Ų153103.9 Ų103.972%0.71556%0.562SS**SBendtrans-70.8-40.2178-179.5170-160.200112.2
723V81.6Confident85.8Confident115 Ų115106.5 Ų106.570%0.69755%0.554SS**  trans-105.2115.5176.8-176.90000108.4
724V75.1Confident85.9Confident67 Ų67104.7 Ų104.741%0.40655%0.547SS..  trans-97.1118.5170.1-1700000103.9P294 Q295P294-V724 HydrophobicContact CB-CG1 3.95Å; P294-V724 HydrophobicContact CG-CG1 3.98Å; Q295-V724 HydrophobicContact CG-CG1 4.08Å
725G77.9Confident85.9Confident40 Ų40105.8 Ų105.841%0.41254%0.541SS..  trans-57.7-175-169.800000114.4P294P294-G725 WeakPolarHBondContact CB-O 3.35Å; P294-G725 WeakPolarHBondContact CG-O 3.38Å
726H72Confident85.8Confident191 Ų191101.7 Ų101.788%0.88453%0.526SS*.  trans-102.1131.3177.9-58.6-66.3000110.3
727C75.8Confident85.6Confident46 Ų46100.4 Ų100.431%0.31153%0.528SS..  trans-137.7145.6163.574.40000109.2V292 P294V292-C727 WeakPolarHBondContact CB-O 3.34Å; V292-C727 WeakPolarHBondContact CG1-O 3.48Å; P294-C727 WeakPolarHBondContact CA-SG 3.19Å
728V75.6Confident85.4Confident122 Ų122101.4 Ų101.474%0.73954%0.538SS*.  trans-137140.9164.8-175.50000105.4
729T74.8Confident85.2Confident58 Ų58102.7 Ų102.736%0.35654%0.544SS..  trans-65.8135.6173.71800000109.8E382 K731E382-T729 HydrophobicContact CB-CG2 3.95Å; E382-T729 HydrophobicContact CG-CG2 4.4Å; T729-K731 PolarHBondContact OG1-N 3.12Å
730D80.4Confident84.9Confident152 Ų15299 Ų9981%0.81354%0.542SS*.  trans-94.5-2.8172.162.1-18.3000112.2
731K83.7Confident84.8Confident167 Ų16797.5 Ų97.573%0.72654%0.537SS*.PPolyproline II helixtrans-72.9125.5-178.1-62.7-177.5-177.8175.50110.7T729T729-K731 PolarHBondContact OG1-N 3.12Å
732P87.1Confident84.8Confident114 Ų11497.7 Ų97.774%0.7454%0.537SS*.PPolyproline II helixtrans-67.9158.617429.4-34.7000111.1F734P732-F734 PolarHBondContact O-N 3.43Å
733F91.6Very high84.8Confident124 Ų12495 Ų9554%0.54453%0.528SS..PPolyproline II helixtrans-55.5137.3169.5177.8-99.9000110.4A375 P376 I378 Y735A375-F733 HydrophobicContact CB-CE2 4.03Å; A375-F733 HydrophobicContact CB-CZ 4.22Å; P376-F733 WeakPolarHBondContact O-CD2 3.47Å; I378-F733 HydrophobicContact CD1-CE2 4.32Å; F733-Y735 HydrophobicContact CZ-CD2 4.43Å; F733-Y735 HydrophobicContact CZ-CG 4.42Å
734F91.4Very high85Confident106 Ų10693.9 Ų93.947%0.46552%0.519SS..  trans-139.4137.9176174.3-82.4000109.2P732 N736P732-F734 PolarHBondContact O-N 3.43Å; F734-N736 HydrophobicContact CE1-CB 3.95Å; F734-N736 HydrophobicContact CZ-CB 4.05Å
735Y95.7Very high85.6Confident108 Ų10895.4 Ų95.442%0.42453%0.525SS..  trans-145.3133.9174.4-164.5-102.6000108.5E373 A375 F733 G737E373-Y735 HydrophobicContact CB-CE2 3.89Å; E373-Y735 HydrophobicContact CG-CD2 4.11Å; E373-Y735 HydrophobicContact CG-CE2 3.82Å; E373-Y735 VanDerWaalsContact O-CE2 3.29Å; E373-Y735 WeakPolarHBondContact O-CE2 3.49Å; E373-Y735 PolarHBondContact O-OH 3.16Å; A375-Y735 HydrophobicContact CB-CD2 4.04Å; A375-Y735 HydrophobicContact CB-CE2 4.08Å; F733-Y735 HydrophobicContact CZ-CD2 4.43Å; F733-Y735 HydrophobicContact CZ-CG 4.42Å; Y735-G737 VanDerWaalsContact CE1-CA 3.45Å
736N94.1Very high86Confident69 Ų6998.6 Ų98.637%0.36953%0.532SS..  trans-93.6-44.6177.8-177.5-85.4000112.1E373 K402 F734 T738E373-N736 VanDerWaalsContact CD-N 3.33Å; E373-N736 PolarHBondContact OE1-N 3.06Å; E373-N736 VanDerWaalsContact OE1-N 3.11Å; E373-N736 VanDerWaalsContact OE2-CA 3.29Å; E373-N736 WeakPolarHBondContact OE2-CA 3.19Å; E373-N736 WeakPolarHBondContact OE2-CB 3.34Å; E373-N736 PolarHBondContact OE2-N 3.06Å; K402-N736 HydrophobicContact CD-CB 4.2Å; F734-N736 HydrophobicContact CE1-CB 3.95Å; F734-N736 HydrophobicContact CZ-CB 4.05Å; N736-T738 VanDerWaalsContact C-N 3.27Å; N736-T738 PolarHBondContact O-N 3.39Å; N736-T738 WeakPolarHBondContact OD1-CB 3.35Å; N736-T738 PolarHBondContact OD1-N 2.92Å; N736-T738 VanDerWaalsContact OD1-N 3.12Å; N736-T738 PolarHBondContact OD1-OG1 3.14Å
737G92.6Very high86.9Confident45 Ų4592.9 Ų92.946%0.46451%0.51SS..  trans76.71.3177.800000115.6E373 Y735E373-G737 PolarHBondContact OE2-N 3.38Å; Y735-G737 VanDerWaalsContact CE1-CA 3.45Å
738T93.1Very high87.6Confident90 Ų9096 Ų9655%0.55252%0.523SS*.  trans-115.5140.9179.4760000112.5N736N736-T738 VanDerWaalsContact C-N 3.27Å; N736-T738 PolarHBondContact O-N 3.39Å; N736-T738 WeakPolarHBondContact OD1-CB 3.35Å; N736-T738 PolarHBondContact OD1-N 2.92Å; N736-T738 VanDerWaalsContact OD1-N 3.12Å; N736-T738 PolarHBondContact OD1-OG1 3.14Å
739Y91.3Very high88.5Confident133 Ų13394.1 Ų94.152%0.52251%0.508SS..  trans-116.5130.716656.3-86.7000107.8Y372 T399 R400Y372-Y739 AromaticContact CD1-CD1 3.77Å; Y372-Y739 HydrophobicContact CD1-CD1 3.77Å; Y372-Y739 HydrophobicContact CD1-CE1 4.03Å; Y372-Y739 HydrophobicContact CD1-CG 4.45Å; Y372-Y739 AromaticContact CE1-CD1 3.69Å; Y372-Y739 HydrophobicContact CE1-CD1 3.69Å; Y372-Y739 AromaticContact CE1-CE1 3.53Å; Y372-Y739 HydrophobicContact CE1-CE1 3.53Å; Y372-Y739 HydrophobicContact CE1-CG 4.31Å; T399-Y739 HydrophobicContact CG2-CD2 3.94Å; R400-Y739 WeakPolarHBondContact O-CA 3.43Å
740A88.8Confident89.5Confident55 Ų5596.9 Ų96.946%0.45552%0.519SS..EExtended strand (participates in β ladder)trans-145.3151.1-170.700000111.9R400R400-A740 PolarHBondContact N-O 2.84Å; R400-A740 PolarHBondContact O-N 3.04Å
741G87.6Confident90.3Very high21 Ų2192.3 Ų92.322%0.21650%0.495CS..EExtended strand (participates in β ladder)trans-74.2134.5179.300000113.4K397 P398K397-G741 PolarHBondContact NZ-O 2.85Å; P398-G741 CarbonylContact O-C 3.59Å; P398-G741 WeakPolarHBondContact O-CA 3.2Å
742V86.8Confident90.9Very high76 Ų7685.5 Ų85.546%0.46147%0.474SS..  trans-117.90-171.8-67.30000115.2V36 K40 Y390 P398 R400V36-V742 HydrophobicContact CG1-CG2 4.1Å; V36-V742 HydrophobicContact CG2-CG2 3.9Å; K40-V742 WeakPolarHBondContact CE-O 3.43Å; K40-V742 VanDerWaalsContact NZ-C 3.26Å; K40-V742 PolarHBondContact NZ-O 2.87Å; K40-V742 PolarHBondContact NZ-OXT 2.94Å; Y390-V742 HydrophobicContact CD1-CG2 4Å; Y390-V742 HydrophobicContact CE1-CG2 4Å; P398-V742 HydrophobicContact CB-CG2 4.27Å; P398-V742 WeakPolarHBondContact O-CG2 3.24Å; P398-V742 PolarHBondContact O-N 2.91Å; R400-V742 HydrophobicContact CB-CG1 3.84Å; R400-V742 HydrophobicContact CB-CG2 4.37Å

Retrieved 742 of 742 residues in 1257.8 ms (Link to these results)