A0A087Y4Z5_POEFO Loading...

Solute carrier family 7 member 7

AlphaFold DB , UniProt , Accession A0A087Y4Z5, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 498 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	T	35.1	Very low	27.3	Very low	201 Å²	201	150.9 Å²	150.9	100%	1.233	88%	0.878	S	S	*	*				0	82.3	0	15.3	0	0	0	0	107.9
2	M	25.5	Very low	27.4	Very low	198 Å²	198	154.8 Å²	154.8	98%	0.975	88%	0.882	S	S	*	*	P	Polyproline II helix	trans	-93.8	135.6	178.8	-88.1	-175.2	-175.3	0	0	109.2
3	A	25.8	Very low	27.5	Very low	105 Å²	105	148.9 Å²	148.9	87%	0.868	88%	0.876	S	S	*	*	P	Polyproline II helix	trans	-67	129	-177.7	0	0	0	0	0	111.7
4	S	25.8	Very low	27.7	Very low	109 Å²	109	147.6 Å²	147.6	76%	0.762	87%	0.87	S	S	*	*	P	Polyproline II helix	trans	-76	129.7	169.4	46.2	0	0	0	0	110.3
5	Y	26.1	Very low	27.9	Very low	227 Å²	227	148.9 Å²	148.9	89%	0.89	87%	0.872	S	S	*	*			trans	-96.4	115	170.2	-163.4	-94	0	0	0	108.1
6	T	24.1	Very low	27.9	Very low	119 Å²	119	144.6 Å²	144.6	73%	0.73	87%	0.869	S	S	*	*	P	Polyproline II helix	trans	-101.4	134.2	174.2	29.1	0	0	0	0	109.8
7	P	28.1	Very low	27.9	Very low	117 Å²	117	140.5 Å²	140.5	76%	0.76	86%	0.863	S	S	*	*	P	Polyproline II helix	trans	-88.2	148.2	163.7	13	4.5	0	0	0	111.5
8	S	24.5	Very low	28.4	Very low	113 Å²	113	140.2 Å²	140.2	79%	0.79	86%	0.864	S	S	*	*	P	Polyproline II helix	trans	-67.8	159	-172.5	-28.2	0	0	0	0	114.9
9	P	27.3	Very low	28.5	Very low	129 Å²	129	142.7 Å²	142.7	84%	0.838	87%	0.867	S	S	*	*	P	Polyproline II helix	trans	-83.9	140.2	176.6	34	-30.5	0	0	0	111.4
10	T	28.4	Very low	29.1	Very low	144 Å²	144	142 Å²	142	88%	0.883	87%	0.868	S	S	*	*	P	Polyproline II helix	trans	-103.2	136.5	164.2	28.7	0	0	0	0	110.1
11	E	29.4	Very low	29	Very low	198 Å²	198	139.3 Å²	139.3	93%	0.925	86%	0.861	S	S	*	*	P	Polyproline II helix	trans	-62	157	-168	-68.9	172.9	141.8	0	0	116.2
12	E	28.2	Very low	28.7	Very low	198 Å²	198	139 Å²	139	93%	0.925	84%	0.843	S	S	*	*	P	Polyproline II helix	trans	-63.1	143.2	178.1	-64.3	175.6	143.2	0	0	113.9
13	G	29	Very low	28.8	Very low	78 Å²	78	134.9 Å²	134.9	80%	0.804	83%	0.833	S	S	*	*			trans	-142.5	104.4	160.2	0	0	0	0	0	109.6
14	T	30.3	Very low	28.9	Very low	130 Å²	130	137.8 Å²	137.8	80%	0.798	83%	0.829	S	S	*	*			trans	-73.6	133.5	-177.6	5.8	0	0	0	0	112.5
15	N	30.8	Very low	28.9	Very low	168 Å²	168	137.9 Å²	137.9	90%	0.898	83%	0.83	S	S	*	*			trans	176.9	116.6	132.1	-92.4	-23.6	0	0	0	114.2
16	G	28.4	Very low	29	Very low	80 Å²	80	131.1 Å²	131.1	83%	0.825	82%	0.816	S	S	*	*				81.1	97.4	126.8	0	0	0	0	0	122.7
17	G	27.3	Very low	29.3	Very low	75 Å²	75	134.6 Å²	134.6	77%	0.773	82%	0.823	S	S	*	*			trans	85.1	149.9	137.4	0	0	0	0	0	119.4
18	P	38	Very low	29.5	Very low	134 Å²	134	137.1 Å²	137.1	87%	0.87	83%	0.825	S	S	*	*			trans	-100	136.8	-137.7	36.2	-30.8	0	0	0	114
19	M	29.7	Very low	29.8	Very low	189 Å²	189	135.3 Å²	135.3	93%	0.931	81%	0.813	S	S	*	*			trans	-139.4	116.4	157.3	-130.7	163.4	76.2	0	0	110.6	A21	M19-A21 PolarHBondContact O-N 3.23Å
20	S	39.7	Very low	30.1	Very low	127 Å²	127	138.3 Å²	138.3	89%	0.888	82%	0.818	S	S	*	*			trans	-51.8	116.2	173.1	178.1	0	0	0	0	111.5
21	A	27.8	Very low	30.8	Very low	87 Å²	87	139.7 Å²	139.7	72%	0.719	81%	0.811	S	S	*	*			trans	-161.8	88.6	151.4	0	0	0	0	0	108.2	M19 S23	M19-A21 PolarHBondContact O-N 3.23Å; A21-S23 PolarHBondContact O-N 3.13Å; A21-S23 VanDerWaalsContact O-N 3.08Å
22	K	29	Very low	32	Very low	195 Å²	195	134.8 Å²	134.8	85%	0.848	79%	0.791	S	S	*	*			trans	-65.3	102.7	157.6	-84.3	-179.2	173.7	-177.5	0	106.5	E24	K22-E24 VanDerWaalsContact C-N 3.26Å; K22-E24 PolarHBondContact O-N 3.32Å; K22-E24 VanDerWaalsContact O-N 3.1Å
23	S	26.2	Very low	33.6	Very low	111 Å²	111	133 Å²	133	78%	0.776	78%	0.78	S	S	*	*			trans	-73.6	89.9	158.7	57.1	0	0	0	0	106.8	A21 S25	A21-S23 PolarHBondContact O-N 3.13Å; A21-S23 VanDerWaalsContact O-N 3.08Å; S23-S25 VanDerWaalsContact C-N 3.32Å; S23-S25 PolarHBondContact O-N 3.26Å
24	E	27.9	Very low	35.8	Very low	166 Å²	166	135.4 Å²	135.4	78%	0.776	77%	0.768	S	S	*	*			trans	-60.2	103.2	158	-77.9	176.5	170.3	0	0	106.5	K22 S26	K22-E24 VanDerWaalsContact C-N 3.26Å; K22-E24 PolarHBondContact O-N 3.32Å; K22-E24 VanDerWaalsContact O-N 3.1Å; E24-S26 PolarHBondContact O-N 2.95Å
25	S	27.8	Very low	38	Very low	111 Å²	111	135.3 Å²	135.3	78%	0.776	76%	0.759	S	S	*	*			trans	-68.6	82.3	160.1	53.7	0	0	0	0	106.6	S23 E27	S23-S25 VanDerWaalsContact C-N 3.32Å; S23-S25 PolarHBondContact O-N 3.26Å; S25-E27 PolarHBondContact O-N 2.79Å
26	S	28	Very low	40.3	Very low	85 Å²	85	128.3 Å²	128.3	59%	0.594	72%	0.721	S	S	*	*			trans	-59.5	108.2	162	50.2	0	0	0	0	106.6	E24 E28	E24-S26 PolarHBondContact O-N 2.95Å; S26-E28 PolarHBondContact O-N 3.17Å
27	E	30.5	Very low	43.1	Very low	191 Å²	191	126.2 Å²	126.2	89%	0.893	69%	0.694	S	S	*	*			trans	-59.3	84.7	156.8	-76.1	-180	160.3	0	0	106.6	S25 S29	S25-E27 PolarHBondContact O-N 2.79Å; E27-S29 PolarHBondContact O-N 3.38Å
28	E	30.4	Very low	45.9	Very low	171 Å²	171	125.1 Å²	125.1	80%	0.799	67%	0.67	S	S	*	*			trans	-67.7	88.8	170.2	-81.8	-166.7	152.1	0	0	106.9	S26 M30	S26-E28 PolarHBondContact O-N 3.17Å; E28-M30 PolarHBondContact O-N 2.96Å; E28-M30 VanDerWaalsContact O-N 3.07Å
29	S	31.1	Very low	48	Very low	75 Å²	75	124.2 Å²	124.2	52%	0.524	66%	0.657	S	S	.	*			trans	-45.1	120.9	161.3	59.4	0	0	0	0	107.6	E27 K31	E27-S29 PolarHBondContact O-N 3.38Å; S29-K31 PolarHBondContact O-N 3.1Å; S29-K31 WeakPolarHBondContact OG-CE 3.28Å
30	M	33.6	Very low	50.4	Low	192 Å²	192	119.1 Å²	119.1	95%	0.946	63%	0.634	S	S	*	*			trans	-72.1	79	-172.3	-152.8	-172.5	-71.7	0	0	108.9	E28	E28-M30 PolarHBondContact O-N 2.96Å; E28-M30 VanDerWaalsContact O-N 3.07Å
31	K	43.7	Very low	52.5	Low	173 Å²	173	113.2 Å²	113.2	75%	0.752	59%	0.593	S	S	*	*	P	Polyproline II helix	trans	-76.4	138.3	-179.2	-70.7	179.2	-178.7	173.1	0	110.3	S29 K33	S29-K31 PolarHBondContact O-N 3.1Å; S29-K31 WeakPolarHBondContact OG-CE 3.28Å; K31-K33 PolarHBondContact O-N 3.07Å
32	L	54.8	Low	55.2	Low	95 Å²	95	110.1 Å²	110.1	50%	0.497	57%	0.565	S	S	.	*	P	Polyproline II helix	trans	-57.6	133.9	173.9	-68.8	172.7	0	0	0	110.2	E249 E250	L32-E249 HydrophobicContact CD1-CB 4.5Å; L32-E250 HydrophobicContact CB-CG 4.2Å; L32-E250 HydrophobicContact CD1-CG 4.23Å
33	K	62.2	Low	57.7	Low	159 Å²	159	103.2 Å²	103.2	69%	0.691	54%	0.541	S	S	*	.	P	Polyproline II helix	trans	-71.5	131.1	-179.6	-70.1	-174.2	179	-178.8	0	110.4	K31 E35	K31-K33 PolarHBondContact O-N 3.07Å; K33-E35 HydrophobicContact CB-CG 3.89Å; K33-E35 WeakPolarHBondContact CD-OE1 3.43Å; K33-E35 PolarHBondContact O-N 3.47Å
34	K	73.8	Confident	60.3	Low	129 Å²	129	100.2 Å²	100.2	56%	0.561	52%	0.516	S	S	*	.			trans	-76.4	84.4	175.4	-68	-178.7	179.8	-179.7	0	111.1	E249 E250 K252	K34-E249 WeakPolarHBondContact CG-O 3.45Å; K34-E250 CarbonylContact C-O 3.29Å; K34-E250 VanDerWaalsContact CA-O 3.31Å; K34-E250 WeakPolarHBondContact CA-O 3.3Å; K34-K252 HydrophobicContact CB-CG 4.36Å; K34-K252 WeakPolarHBondContact O-CE 3.29Å; K34-K252 VanDerWaalsContact O-CG 3.31Å; K34-K252 WeakPolarHBondContact O-CG 3.28Å
35	E	77.8	Confident	62.9	Low	128 Å²	128	92.3 Å²	92.3	60%	0.598	48%	0.479	S	S	*	.			trans	-106.2	-20.4	-174.5	-65.8	-173.4	175.1	0	0	113.7	K33 S37 E250	K33-E35 HydrophobicContact CB-CG 3.89Å; K33-E35 WeakPolarHBondContact CD-OE1 3.43Å; K33-E35 PolarHBondContact O-N 3.47Å; E35-S37 PolarHBondContact O-N 3.19Å; E35-E250 PolarHBondContact N-O 3.08Å
36	I	78.4	Confident	65.7	Low	22 Å²	22	88 Å²	88	11%	0.113	45%	0.448	C	S	.	.	B	Isolated β-bridge	trans	-78.2	113.2	-173.2	-55.4	178.4	0	0	0	110.5	N40 V247 E250 I251 K252	I36-N40 HydrophobicContact CG2-CB 4.01Å; I36-V247 HydrophobicContact CD1-CB 4.04Å; I36-V247 HydrophobicContact CD1-CG2 3.85Å; I36-E250 HydrophobicContact CD1-CB 3.78Å; I36-E250 HydrophobicContact CG1-CB 4.13Å; I36-E250 PolarHBondContact N-O 3.16Å; I36-I251 HydrophobicContact CB-CG1 4.25Å; I36-I251 HydrophobicContact CG2-CG1 4.26Å; I36-K252 PolarHBondContact O-N 3.09Å
37	S	87.1	Confident	68.1	Low	36 Å²	36	84.1 Å²	84.1	25%	0.252	42%	0.421	S	S	.	.			trans	-80.2	169.4	174.3	79.5	0	0	0	0	112.2	E35 L39 N40 G41	E35-S37 PolarHBondContact O-N 3.19Å; S37-L39 VanDerWaalsContact C-N 3.34Å; S37-L39 PolarHBondContact O-N 3.14Å; S37-N40 PolarHBondContact O-N 3.32Å; S37-N40 PolarHBondContact OG-N 3.39Å; S37-N40 PolarHBondContact OG-OD1 2.93Å; S37-N40 VanDerWaalsContact OG-OD1 3.11Å; S37-G41 PolarHBondContact O-N 2.86Å
38	L	85.9	Confident	70.4	Confident	52 Å²	52	77 Å²	77	27%	0.272	39%	0.39	S	S	.	.	H	α-helix	trans	-56.4	-46	174.9	176.4	62.4	0	0	0	112.4	G41 V42 N257 L260 A261	L38-G41 WeakPolarHBondContact O-CA 3.33Å; L38-G41 PolarHBondContact O-N 3.49Å; L38-G41 VanDerWaalsContact O-N 3.15Å; L38-V42 WeakPolarHBondContact O-CG2 3.42Å; L38-V42 PolarHBondContact O-N 3.33Å; L38-N257 HydrophobicContact CB-CB 4.43Å; L38-N257 HydrophobicContact CD1-CB 4.27Å; L38-N257 WeakPolarHBondContact CD1-O 3.49Å; L38-L260 HydrophobicContact CD1-CB 3.7Å; L38-L260 HydrophobicContact CD2-CB 4.46Å; L38-L260 HydrophobicContact CD2-CD1 4.41Å; L38-A261 HydrophobicContact CD1-CB 4.04Å
39	L	82.6	Confident	73	Confident	114 Å²	114	69.1 Å²	69.1	60%	0.597	35%	0.353	S	S	*	.	H	α-helix	trans	-66.6	-41.4	-179.3	-170.4	148.2	0	0	0	110.9	S37 G41 V42 C43	S37-L39 VanDerWaalsContact C-N 3.34Å; S37-L39 PolarHBondContact O-N 3.14Å; L39-G41 PolarHBondContact O-N 3.3Å; L39-V42 PolarHBondContact O-N 2.68Å; L39-C43 WeakPolarHBondContact O-CB 3.46Å; L39-C43 PolarHBondContact O-N 3.14Å; L39-C43 PolarHBondContact O-SG 3.12Å; L39-C43 VanDerWaalsContact O-SG 3.39Å
40	N	80.6	Confident	75.5	Confident	83 Å²	83	65.5 Å²	65.5	44%	0.444	33%	0.328	S	S	.	.	H	α-helix	trans	-59.8	-39.9	173.2	-61.5	3.1	0	0	0	110.4	I36 S37 C43 L44	I36-N40 HydrophobicContact CG2-CB 4.01Å; S37-N40 PolarHBondContact O-N 3.32Å; S37-N40 PolarHBondContact OG-N 3.39Å; S37-N40 PolarHBondContact OG-OD1 2.93Å; S37-N40 VanDerWaalsContact OG-OD1 3.11Å; N40-C43 PolarHBondContact O-N 2.94Å; N40-L44 VanDerWaalsContact O-CB 3.25Å; N40-L44 WeakPolarHBondContact O-CB 3.44Å; N40-L44 PolarHBondContact O-N 3.2Å
41	G	82.6	Confident	77.6	Confident	3 Å²	3	56.8 Å²	56.8	3%	0.031	29%	0.287	C	S	.	.	H	α-helix	trans	-62.9	-45.6	176.3	0	0	0	0	0	113.3	S37 L38 L39 L44 I45	S37-G41 PolarHBondContact O-N 2.86Å; L38-G41 WeakPolarHBondContact O-CA 3.33Å; L38-G41 PolarHBondContact O-N 3.49Å; L38-G41 VanDerWaalsContact O-N 3.15Å; L39-G41 PolarHBondContact O-N 3.3Å; G41-L44 PolarHBondContact O-N 3.39Å; G41-I45 PolarHBondContact O-N 3.18Å
42	V	86.2	Confident	79.3	Confident	22 Å²	22	49 Å²	49	13%	0.133	25%	0.254	C	S	.	.	H	α-helix	trans	-61.1	-48.5	174.8	174.1	0	0	0	0	110.7	L38 L39 L44 I45 V46 A261 I264	L38-V42 WeakPolarHBondContact O-CG2 3.42Å; L38-V42 PolarHBondContact O-N 3.33Å; L39-V42 PolarHBondContact O-N 2.68Å; V42-L44 VanDerWaalsContact C-N 3.26Å; V42-L44 PolarHBondContact O-N 2.82Å; V42-I45 PolarHBondContact O-N 2.9Å; V42-V46 HydrophobicContact CG1-CG2 4.15Å; V42-V46 WeakPolarHBondContact O-CB 3.33Å; V42-V46 VanDerWaalsContact O-CG2 3.29Å; V42-V46 WeakPolarHBondContact O-CG2 3.36Å; V42-V46 PolarHBondContact O-N 3.32Å; V42-A261 HydrophobicContact CG2-CB 4.14Å; V42-I264 HydrophobicContact CG1-CG2 4.1Å; V42-I264 HydrophobicContact CG2-CB 4.18Å; V42-I264 HydrophobicContact CG2-CD1 4.44Å; V42-I264 HydrophobicContact CG2-CG2 4.16Å
43	C	80.9	Confident	80.8	Confident	49 Å²	49	44.7 Å²	44.7	33%	0.331	23%	0.233	S	C	.	.	H	α-helix	trans	-60.5	-36.6	177.8	-71	0	0	0	0	112.3	L39 N40 G47	L39-C43 WeakPolarHBondContact O-CB 3.46Å; L39-C43 PolarHBondContact O-N 3.14Å; L39-C43 PolarHBondContact O-SG 3.12Å; L39-C43 VanDerWaalsContact O-SG 3.39Å; N40-C43 PolarHBondContact O-N 2.94Å; C43-G47 WeakPolarHBondContact O-CA 3.41Å; C43-G47 PolarHBondContact O-N 3.47Å
44	L	79.6	Confident	82.2	Confident	49 Å²	49	37.1 Å²	37.1	26%	0.257	20%	0.2	S	C	.	.	H	α-helix	trans	-67.9	-46	177.5	-169.9	160.9	0	0	0	111.4	N40 G41 V42 N48 T243 L244	N40-L44 VanDerWaalsContact O-CB 3.25Å; N40-L44 WeakPolarHBondContact O-CB 3.44Å; N40-L44 PolarHBondContact O-N 3.2Å; G41-L44 PolarHBondContact O-N 3.39Å; V42-L44 VanDerWaalsContact C-N 3.26Å; V42-L44 PolarHBondContact O-N 2.82Å; L44-N48 WeakPolarHBondContact O-CB 3.42Å; L44-N48 PolarHBondContact O-N 3.33Å; L44-T243 HydrophobicContact CD2-CG2 3.83Å; L44-L244 HydrophobicContact CB-CD2 4.26Å; L44-L244 HydrophobicContact CD1-CD2 4.01Å; L44-L244 HydrophobicContact CD2-CD2 3.85Å; L44-L244 HydrophobicContact CD2-CG 4.26Å; L44-L244 HydrophobicContact CG-CD2 4.27Å
45	I	84.4	Confident	82.9	Confident	0 Å²	0	31.2 Å²	31.2	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-63.2	-53.6	176.1	-66.1	172.9	0	0	0	110.6	G41 V42 G47 N48 M49 W241 L244 A261 I262 S265	G41-I45 PolarHBondContact O-N 3.18Å; V42-I45 PolarHBondContact O-N 2.9Å; I45-G47 VanDerWaalsContact C-N 3.27Å; I45-G47 PolarHBondContact O-N 3.42Å; I45-N48 PolarHBondContact O-N 3.37Å; I45-M49 HydrophobicContact CG2-CG 4.05Å; I45-M49 HydrophobicContact CG2-SD 3.44Å; I45-M49 WeakPolarHBondContact CG2-SD 3.35Å; I45-M49 WeakPolarHBondContact O-CB 3.27Å; I45-M49 WeakPolarHBondContact O-CG 3.41Å; I45-M49 PolarHBondContact O-N 2.99Å; I45-W241 HydrophobicContact CG2-CB 4.45Å; I45-L244 HydrophobicContact CD1-CD1 3.34Å; I45-L244 HydrophobicContact CD1-CG 3.92Å; I45-L244 HydrophobicContact CG1-CD1 3.6Å; I45-L244 HydrophobicContact CG1-CG 3.66Å; I45-A261 HydrophobicContact CD1-CB 4.17Å; I45-I262 HydrophobicContact CD1-CG1 3.68Å; I45-S265 WeakPolarHBondContact CD1-OG 3.32Å; I45-S265 VanDerWaalsContact CG2-OG 3.27Å; I45-S265 WeakPolarHBondContact CG2-OG 3.46Å
46	V	84.8	Confident	83.6	Confident	19 Å²	19	25.8 Å²	25.8	12%	0.115	15%	0.15	C	C	.	.	H	α-helix	trans	-59.8	-43.3	-178.3	174.1	0	0	0	0	110	V42 I50 V269	V42-V46 HydrophobicContact CG1-CG2 4.15Å; V42-V46 WeakPolarHBondContact O-CB 3.33Å; V42-V46 VanDerWaalsContact O-CG2 3.29Å; V42-V46 WeakPolarHBondContact O-CG2 3.36Å; V42-V46 PolarHBondContact O-N 3.32Å; V46-I50 HydrophobicContact CG1-CD1 3.53Å; V46-I50 HydrophobicContact CG1-CG1 4.17Å; V46-I50 WeakPolarHBondContact O-CB 3.45Å; V46-I50 VanDerWaalsContact O-CG1 3.27Å; V46-I50 WeakPolarHBondContact O-CG1 3.39Å; V46-I50 PolarHBondContact O-N 2.94Å; V46-V269 HydrophobicContact CG1-CG2 4.48Å; V46-V269 HydrophobicContact CG2-CG2 4.21Å
47	G	78.8	Confident	84.3	Confident	4 Å²	4	24.7 Å²	24.7	4%	0.041	14%	0.144	C	C	.	.	H	α-helix	trans	-65.8	-35.7	178.2	0	0	0	0	0	113.6	C43 I45 K190	C43-G47 WeakPolarHBondContact O-CA 3.41Å; C43-G47 PolarHBondContact O-N 3.47Å; I45-G47 VanDerWaalsContact C-N 3.27Å; I45-G47 PolarHBondContact O-N 3.42Å; G47-K190 WeakPolarHBondContact O-CE 3.24Å; G47-K190 PolarHBondContact O-NZ 3.48Å
48	N	78.6	Confident	84.7	Confident	43 Å²	43	23 Å²	23	23%	0.23	13%	0.132	C	C	.	.	H	α-helix	trans	-80.4	-40.5	178.1	-76.8	-4.6	0	0	0	112.5	L44 I45 T243	L44-N48 WeakPolarHBondContact O-CB 3.42Å; L44-N48 PolarHBondContact O-N 3.33Å; I45-N48 PolarHBondContact O-N 3.37Å; N48-T243 WeakPolarHBondContact ND2-CB 3.48Å; N48-T243 WeakPolarHBondContact ND2-CG2 3.41Å; N48-T243 PolarHBondContact ND2-OG1 3.41Å; N48-T243 VanDerWaalsContact ND2-OG1 3.11Å
49	M	85.3	Confident	85.1	Confident	4 Å²	4	21.9 Å²	21.9	2%	0.02	13%	0.125	C	C	.	.	H	α-helix	trans	-66.5	-51.5	178.2	-70.6	178.7	77.9	0	0	111.3	I45 G51 Y238 S239 W241 M266 V269 Y273	I45-M49 HydrophobicContact CG2-CG 4.05Å; I45-M49 HydrophobicContact CG2-SD 3.44Å; I45-M49 WeakPolarHBondContact CG2-SD 3.35Å; I45-M49 WeakPolarHBondContact O-CB 3.27Å; I45-M49 WeakPolarHBondContact O-CG 3.41Å; I45-M49 PolarHBondContact O-N 2.99Å; M49-G51 PolarHBondContact O-N 3.4Å; M49-Y238 HydrophobicContact CE-CD1 3.81Å; M49-Y238 VanDerWaalsContact CE-O 3.22Å; M49-Y238 WeakPolarHBondContact CE-O 3.45Å; M49-S239 WeakPolarHBondContact CA-O 3.31Å; M49-W241 HydrophobicContact CE-CB 4.39Å; M49-W241 HydrophobicContact CG-CB 4.45Å; M49-W241 HydrophobicContact SD-CB 3.86Å; M49-M266 HydrophobicContact CE-CE 3.59Å; M49-M266 HydrophobicContact CE-SD 3.6Å; M49-M266 VanDerWaalsContact CE-SD 3.6Å; M49-M266 HydrophobicContact SD-CE 4.41Å; M49-M266 HydrophobicContact SD-SD 3.6Å; M49-M266 VanDerWaalsContact SD-SD 3.6Å; M49-V269 HydrophobicContact CB-CG1 4.24Å; M49-V269 HydrophobicContact CB-CG2 4.27Å; M49-V269 HydrophobicContact CE-CB 4.25Å; M49-V269 HydrophobicContact CE-CG1 3.85Å; M49-V269 HydrophobicContact CE-CG2 4.48Å; M49-V269 HydrophobicContact SD-CB 4.48Å; M49-V269 HydrophobicContact SD-CG1 4.44Å; M49-V269 HydrophobicContact SD-CG2 4.08Å; M49-Y273 VanDerWaalsContact C-OH 3.25Å; M49-Y273 PolarHBondContact O-OH 3.36Å
50	I	84.5	Confident	85.6	Confident	0 Å²	0	16.5 Å²	16.5	0%	0	10%	0.097	C	C	.	.	S	Bend	trans	-71.7	80.4	178	-57.9	-175.9	0	0	0	108.4	V46 K190 L194 V269 I272 Y273	V46-I50 HydrophobicContact CG1-CD1 3.53Å; V46-I50 HydrophobicContact CG1-CG1 4.17Å; V46-I50 WeakPolarHBondContact O-CB 3.45Å; V46-I50 VanDerWaalsContact O-CG1 3.27Å; V46-I50 WeakPolarHBondContact O-CG1 3.39Å; V46-I50 PolarHBondContact O-N 2.94Å; I50-K190 VanDerWaalsContact O-CD 3.24Å; I50-K190 WeakPolarHBondContact O-CD 3.45Å; I50-K190 WeakPolarHBondContact O-CE 3.35Å; I50-K190 PolarHBondContact O-NZ 3.17Å; I50-L194 HydrophobicContact CG2-CD1 3.21Å; I50-V269 HydrophobicContact CD1-CG2 4.28Å; I50-V269 HydrophobicContact CG1-CG1 4.29Å; I50-V269 HydrophobicContact CG1-CG2 4.05Å; I50-I272 HydrophobicContact CD1-CD1 3.81Å; I50-I272 HydrophobicContact CD1-CG2 4.33Å; I50-Y273 WeakPolarHBondContact CA-OH 3.28Å; I50-Y273 HydrophobicContact CG1-CE1 4.09Å
51	G	77.9	Confident	86.4	Confident	9 Å²	9	12.5 Å²	12.5	9%	0.093	8%	0.076	C	C	.	.	S	Bend	trans	-119.8	-144.5	-175.8	0	0	0	0	0	112.7	M49 G53 F55	M49-G51 PolarHBondContact O-N 3.4Å; G51-G53 PolarHBondContact O-N 3.39Å; G51-F55 WeakPolarHBondContact O-CD2 3.05Å; G51-F55 WeakPolarHBondContact O-CE2 3.36Å
52	S	78.3	Confident	87	Confident	8 Å²	8	12.5 Å²	12.5	6%	0.056	8%	0.075	C	C	.	.	S	Bend	trans	-68.6	-22.2	173.2	58.4	0	0	0	0	112.9	I54 F55 V56 I134 C319	S52-I54 PolarHBondContact O-N 2.98Å; S52-F55 WeakPolarHBondContact O-CB 3.03Å; S52-F55 PolarHBondContact O-N 2.84Å; S52-F55 VanDerWaalsContact O-N 3.1Å; S52-V56 PolarHBondContact O-N 3.29Å; S52-I134 VanDerWaalsContact OG-CG1 3.31Å; S52-I134 WeakPolarHBondContact OG-CG1 3.43Å; S52-C319 VanDerWaalsContact CB-SG 3.52Å
53	G	87.1	Confident	87.3	Confident	5 Å²	5	15.1 Å²	15.1	5%	0.052	9%	0.087	C	C	.	.	H	α-helix	trans	-55.4	-50.4	-174.7	0	0	0	0	0	113.2	G51 F55 V56 S57 S237	G51-G53 PolarHBondContact O-N 3.39Å; G53-F55 PolarHBondContact O-N 3.03Å; G53-V56 PolarHBondContact O-N 2.7Å; G53-S57 VanDerWaalsContact O-CB 3.3Å; G53-S57 WeakPolarHBondContact O-CB 3.41Å; G53-S57 PolarHBondContact O-N 2.79Å; G53-S57 PolarHBondContact O-OG 2.55Å; G53-S57 VanDerWaalsContact O-OG 3.13Å; G53-S237 WeakPolarHBondContact CA-OG 3.29Å; G53-S237 PolarHBondContact O-OG 3.3Å
54	I	91.1	Very high	88	Confident	0 Å²	0	14.3 Å²	14.3	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-62.7	-15.7	-177.3	-168.2	54.8	0	0	0	113.4	S52 P58 W75 L194 S237 Y273 T276	S52-I54 PolarHBondContact O-N 2.98Å; I54-P58 WeakPolarHBondContact O-CD 3.41Å; I54-P58 WeakPolarHBondContact O-CG 3.45Å; I54-W75 HydrophobicContact CD1-CH2 3.5Å; I54-W75 VanDerWaalsContact CD1-CH2 3.5Å; I54-W75 HydrophobicContact CD1-CZ2 4.06Å; I54-W75 HydrophobicContact CD1-CZ3 3.93Å; I54-L194 HydrophobicContact CG2-CD1 4.35Å; I54-L194 HydrophobicContact CG2-CD2 4.26Å; I54-S237 PolarHBondContact N-OG 2.77Å; I54-S237 VanDerWaalsContact N-OG 3.16Å; I54-Y273 HydrophobicContact CB-CD1 4.14Å; I54-Y273 HydrophobicContact CB-CE1 3.75Å; I54-Y273 HydrophobicContact CD1-CD1 3.61Å; I54-Y273 HydrophobicContact CD1-CD2 4.47Å; I54-Y273 HydrophobicContact CD1-CE1 4.1Å; I54-Y273 HydrophobicContact CD1-CG 3.8Å; I54-Y273 HydrophobicContact CG1-CD1 3.71Å; I54-Y273 HydrophobicContact CG1-CE1 3.86Å; I54-Y273 HydrophobicContact CG1-CG 4.42Å; I54-Y273 HydrophobicContact CG2-CE1 4.32Å; I54-T276 HydrophobicContact CG1-CG2 4.16Å
55	F	89	Confident	88.6	Confident	5 Å²	5	12 Å²	12	2%	0.022	7%	0.066	C	C	.	.	H	α-helix	trans	-92.9	-14.6	179	-62.9	-58	0	0	0	113.1	G51 S52 G53 T137 Y141 L194 A296 V315	G51-F55 WeakPolarHBondContact O-CD2 3.05Å; G51-F55 WeakPolarHBondContact O-CE2 3.36Å; S52-F55 WeakPolarHBondContact O-CB 3.03Å; S52-F55 PolarHBondContact O-N 2.84Å; S52-F55 VanDerWaalsContact O-N 3.1Å; G53-F55 PolarHBondContact O-N 3.03Å; F55-T137 HydrophobicContact CB-CG2 4.46Å; F55-Y141 HydrophobicContact CB-CE2 3.87Å; F55-Y141 WeakPolarHBondContact CB-OH 3.41Å; F55-Y141 PolarHBondContact O-OH 3.25Å; F55-Y141 VanDerWaalsContact O-OH 3.08Å; F55-L194 HydrophobicContact CE1-CD2 3.84Å; F55-L194 HydrophobicContact CZ-CD2 3.76Å; F55-L194 HydrophobicContact CZ-CG 4.14Å; F55-A296 HydrophobicContact CD1-CB 3.82Å; F55-A296 HydrophobicContact CE1-CB 4.09Å; F55-V315 HydrophobicContact CB-CG1 4.06Å; F55-V315 HydrophobicContact CD1-CG1 4.19Å; F55-V315 HydrophobicContact CD1-CG2 3.74Å; F55-V315 HydrophobicContact CD2-CB 4.42Å; F55-V315 HydrophobicContact CD2-CG1 3.56Å; F55-V315 HydrophobicContact CD2-CG2 4.14Å; F55-V315 HydrophobicContact CE1-CG2 3.52Å; F55-V315 HydrophobicContact CE2-CB 4.44Å; F55-V315 HydrophobicContact CE2-CG1 4.03Å; F55-V315 HydrophobicContact CE2-CG2 3.93Å; F55-V315 HydrophobicContact CG-CG1 3.65Å; F55-V315 HydrophobicContact CG-CG2 4.05Å; F55-V315 HydrophobicContact CZ-CG2 3.62Å
56	V	91.2	Very high	89.1	Confident	14 Å²	14	14.1 Å²	14.1	9%	0.085	8%	0.084	C	C	.	.	H	α-helix	trans	-111.7	-45.9	178.3	178.9	0	0	0	0	111.9	S52 G53 K59 T137 V377 F378 I381	S52-V56 PolarHBondContact O-N 3.29Å; G53-V56 PolarHBondContact O-N 2.7Å; V56-K59 PolarHBondContact O-N 3.37Å; V56-T137 HydrophobicContact CG2-CG2 3.48Å; V56-T137 VanDerWaalsContact CG2-CG2 3.48Å; V56-T137 WeakPolarHBondContact CG2-OG1 3.16Å; V56-V377 HydrophobicContact CG1-CG1 4.3Å; V56-F378 HydrophobicContact CG1-CE1 4.04Å; V56-F378 HydrophobicContact CG1-CZ 4.18Å; V56-I381 HydrophobicContact CG1-CD1 3.92Å
57	S	94.3	Very high	89.5	Confident	0 Å²	0	13.3 Å²	13.3	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-58.2	-33.4	-172.9	-65.8	0	0	0	0	115.4	G53 K59 G60 V61 S233 S237	G53-S57 VanDerWaalsContact O-CB 3.3Å; G53-S57 WeakPolarHBondContact O-CB 3.41Å; G53-S57 PolarHBondContact O-N 2.79Å; G53-S57 PolarHBondContact O-OG 2.55Å; G53-S57 VanDerWaalsContact O-OG 3.13Å; S57-K59 VanDerWaalsContact C-N 3.26Å; S57-K59 PolarHBondContact O-N 2.88Å; S57-G60 PolarHBondContact O-N 3Å; S57-G60 VanDerWaalsContact O-N 3.09Å; S57-V61 VanDerWaalsContact O-CG2 3.31Å; S57-V61 WeakPolarHBondContact O-CG2 3.29Å; S57-V61 PolarHBondContact O-N 3.46Å; S57-S233 WeakPolarHBondContact CB-O 3.46Å; S57-S233 PolarHBondContact OG-O 3.49Å; S57-S237 WeakPolarHBondContact CB-OG 3.16Å; S57-S237 PolarHBondContact OG-OG 2.79Å
58	P	95.1	Very high	90.3	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-54.9	-40	178.4	-29.3	36.7	0	0	0	113.7	I54 L62 W75 N277 Y280	I54-P58 WeakPolarHBondContact O-CD 3.41Å; I54-P58 WeakPolarHBondContact O-CG 3.45Å; P58-L62 VanDerWaalsContact O-CB 3.26Å; P58-L62 WeakPolarHBondContact O-CB 3.39Å; P58-L62 PolarHBondContact O-N 3.28Å; P58-L62 VanDerWaalsContact O-N 3.09Å; P58-W75 HydrophobicContact CG-CZ2 4.17Å; P58-N277 WeakPolarHBondContact CB-OD1 3.21Å; P58-Y280 HydrophobicContact CB-CD2 4.34Å; P58-Y280 HydrophobicContact CG-CD2 4.23Å; P58-Y280 HydrophobicContact CG-CE2 4.05Å
59	K	94.6	Very high	91.1	Very high	29 Å²	29	11.6 Å²	11.6	13%	0.126	7%	0.069	C	C	.	.	H	α-helix	trans	-65	-49.1	174.6	171.8	168.4	170.5	167	0	110.8	V56 S57 V61 L62 I63 L290 S292 D293 V295 F378	V56-K59 PolarHBondContact O-N 3.37Å; S57-K59 VanDerWaalsContact C-N 3.26Å; S57-K59 PolarHBondContact O-N 2.88Å; K59-V61 PolarHBondContact O-N 3.25Å; K59-L62 PolarHBondContact O-N 3.37Å; K59-I63 HydrophobicContact CG-CD1 3.83Å; K59-I63 HydrophobicContact CG-CG1 4.41Å; K59-I63 VanDerWaalsContact O-CG1 3.24Å; K59-I63 WeakPolarHBondContact O-CG1 3.4Å; K59-I63 PolarHBondContact O-N 3.1Å; K59-L290 WeakPolarHBondContact CE-O 3.45Å; K59-L290 PolarHBondContact NZ-O 3.27Å; K59-S292 VanDerWaalsContact CD-O 3.24Å; K59-S292 WeakPolarHBondContact CD-O 3.25Å; K59-S292 PolarHBondContact NZ-O 3.29Å; K59-D293 IonicContact NZ-OD1 2.83Å; K59-D293 PolarHBondContact NZ-OD1 2.68Å; K59-V295 HydrophobicContact CB-CG2 4.29Å; K59-F378 HydrophobicContact CB-CZ 4.14Å; K59-F378 HydrophobicContact CD-CE2 4.37Å; K59-F378 HydrophobicContact CD-CZ 4.35Å; K59-F378 HydrophobicContact CG-CE2 4.23Å; K59-F378 HydrophobicContact CG-CZ 3.91Å
60	G	93.3	Very high	91.6	Very high	0 Å²	0	12.8 Å²	12.8	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-61.7	-42.4	179.7	0	0	0	0	0	114	S57 H64	S57-G60 PolarHBondContact O-N 3Å; S57-G60 VanDerWaalsContact O-N 3.09Å; G60-H64 PolarHBondContact O-CD2 3.44Å; G60-H64 VanDerWaalsContact O-CD2 3.25Å
61	V	96.3	Very high	92.2	Very high	0 Å²	0	12.8 Å²	12.8	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-62.8	-45.8	175.5	178.7	0	0	0	0	110	S57 K59 H64 S65 S71 V74 W75 A230 A234	S57-V61 VanDerWaalsContact O-CG2 3.31Å; S57-V61 WeakPolarHBondContact O-CG2 3.29Å; S57-V61 PolarHBondContact O-N 3.46Å; K59-V61 PolarHBondContact O-N 3.25Å; V61-H64 PolarHBondContact O-N 3.34Å; V61-S65 VanDerWaalsContact O-CB 3.29Å; V61-S65 WeakPolarHBondContact O-CB 3.38Å; V61-S65 PolarHBondContact O-N 3.1Å; V61-S65 PolarHBondContact O-OG 3.11Å; V61-S71 VanDerWaalsContact CG1-OG 3.23Å; V61-S71 WeakPolarHBondContact CG1-OG 3.28Å; V61-V74 HydrophobicContact CG1-CB 4.08Å; V61-V74 HydrophobicContact CG1-CG1 3.89Å; V61-W75 HydrophobicContact CG2-CZ2 4.24Å; V61-A230 HydrophobicContact CG1-CB 4.41Å; V61-A234 HydrophobicContact CG2-CB 3.92Å
62	L	95.1	Very high	93	Very high	2 Å²	2	13.4 Å²	13.4	1%	0.01	8%	0.076	C	C	.	.	H	α-helix	trans	-70.3	-34.6	-176.4	-165.2	64.7	0	0	0	113.3	P58 K59 H64 S65 A66 Y68 Y281 I286 I289 L290	P58-L62 VanDerWaalsContact O-CB 3.26Å; P58-L62 WeakPolarHBondContact O-CB 3.39Å; P58-L62 PolarHBondContact O-N 3.28Å; P58-L62 VanDerWaalsContact O-N 3.09Å; K59-L62 PolarHBondContact O-N 3.37Å; L62-H64 PolarHBondContact O-N 3.3Å; L62-S65 WeakPolarHBondContact CA-OG 3.21Å; L62-A66 WeakPolarHBondContact O-CA 3Å; L62-A66 PolarHBondContact O-N 3.46Å; L62-Y68 HydrophobicContact CD1-CD1 3.82Å; L62-Y68 HydrophobicContact CD1-CE1 4.26Å; L62-Y68 HydrophobicContact CD2-CD1 4.38Å; L62-Y68 HydrophobicContact CD2-CE1 4.04Å; L62-Y281 HydrophobicContact CD2-CE1 4.4Å; L62-I286 HydrophobicContact CD2-CB 4.45Å; L62-I286 HydrophobicContact CD2-CG1 4.43Å; L62-I286 HydrophobicContact CD2-CG2 4.05Å; L62-I286 HydrophobicContact CG-CG2 4.39Å; L62-I289 HydrophobicContact CD2-CB 3.94Å; L62-I289 HydrophobicContact CD2-CD1 4.04Å; L62-I289 HydrophobicContact CD2-CG2 3.86Å; L62-L290 HydrophobicContact CB-CD2 4.28Å; L62-L290 HydrophobicContact CD2-CD2 4.4Å; L62-L290 HydrophobicContact CG-CD2 4.34Å
63	I	94.1	Very high	93.9	Very high	77 Å²	77	15.9 Å²	15.9	40%	0.395	9%	0.09	S	C	.	.	H	α-helix	trans	-53.9	-43.6	173.2	-74.9	166.5	0	0	0	110.5	K59 L290 F378	K59-I63 HydrophobicContact CG-CD1 3.83Å; K59-I63 HydrophobicContact CG-CG1 4.41Å; K59-I63 VanDerWaalsContact O-CG1 3.24Å; K59-I63 WeakPolarHBondContact O-CG1 3.4Å; K59-I63 PolarHBondContact O-N 3.1Å; I63-L290 HydrophobicContact CB-CD2 4.38Å; I63-L290 HydrophobicContact CG1-CD2 3.5Å; I63-F378 HydrophobicContact CD1-CE2 4.25Å
64	H	93.9	Very high	94.4	Very high	32 Å²	32	15.8 Å²	15.8	15%	0.148	9%	0.089	C	C	.	.	H	α-helix	trans	-93.4	-28.7	-174.6	-67.1	-58.9	0	0	0	113.7	G60 V61 L62 S221 H226 A230	G60-H64 PolarHBondContact O-CD2 3.44Å; G60-H64 VanDerWaalsContact O-CD2 3.25Å; V61-H64 PolarHBondContact O-N 3.34Å; L62-H64 PolarHBondContact O-N 3.3Å; H64-S221 WeakPolarHBondContact O-CB 3.33Å; H64-H226 HydrophobicContact CB-CB 4.27Å; H64-H226 VanDerWaalsContact CB-O 3.31Å; H64-H226 WeakPolarHBondContact CB-O 3.39Å; H64-A230 HydrophobicContact CB-CB 3.8Å
65	S	94.2	Very high	94.7	Very high	0 Å²	0	15.8 Å²	15.8	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-78.6	-27.9	176.3	74	0	0	0	0	112.6	V61 L62 S67 S71 S221	V61-S65 VanDerWaalsContact O-CB 3.29Å; V61-S65 WeakPolarHBondContact O-CB 3.38Å; V61-S65 PolarHBondContact O-N 3.1Å; V61-S65 PolarHBondContact O-OG 3.11Å; L62-S65 WeakPolarHBondContact CA-OG 3.21Å; S65-S67 PolarHBondContact O-N 3.2Å; S65-S67 PolarHBondContact OG-O 2.76Å; S65-S71 WeakPolarHBondContact OG-CB 3.49Å; S65-S221 PolarHBondContact O-N 3.16Å
66	A	93.4	Very high	95	Very high	45 Å²	45	18 Å²	18	37%	0.372	10%	0.103	S	C	.	.			trans	58.7	-1.3	-177.4	0	0	0	0	0	116.1	L62 G219	L62-A66 WeakPolarHBondContact O-CA 3Å; L62-A66 PolarHBondContact O-N 3.46Å; A66-G219 VanDerWaalsContact CB-O 3.31Å; A66-G219 WeakPolarHBondContact CB-O 3.24Å
67	S	94.4	Very high	95.2	Very high	2 Å²	2	21.3 Å²	21.3	1%	0.014	12%	0.119	C	C	.	.	S	Bend	trans	-143.1	153.9	176.3	77.9	0	0	0	0	111.3	S65 L70 S71 M216 D218 S220	S65-S67 PolarHBondContact O-N 3.2Å; S65-S67 PolarHBondContact OG-O 2.76Å; S67-L70 VanDerWaalsContact OG-CB 3.22Å; S67-L70 WeakPolarHBondContact OG-CB 3.48Å; S67-L70 PolarHBondContact OG-N 3.39Å; S67-L70 VanDerWaalsContact OG-N 3.13Å; S67-S71 WeakPolarHBondContact O-CB 3.45Å; S67-S71 PolarHBondContact O-N 2.92Å; S67-S71 VanDerWaalsContact O-N 3.08Å; S67-M216 WeakPolarHBondContact CB-O 3.34Å; S67-D218 WeakPolarHBondContact CB-O 3.45Å; S67-S220 WeakPolarHBondContact CB-OG 3.31Å; S67-S220 PolarHBondContact OG-OG 3.01Å
68	Y	94.6	Very high	95.2	Very high	12 Å²	12	21.3 Å²	21.3	5%	0.047	12%	0.119	C	C	.	.	H	α-helix	trans	-67.2	-40.7	176.8	-62	-43.4	0	0	0	112.3	L62 S71 L72 N212 M216 Y281 L284 P285 I286 I289	L62-Y68 HydrophobicContact CD1-CD1 3.82Å; L62-Y68 HydrophobicContact CD1-CE1 4.26Å; L62-Y68 HydrophobicContact CD2-CD1 4.38Å; L62-Y68 HydrophobicContact CD2-CE1 4.04Å; Y68-S71 WeakPolarHBondContact O-CB 3.49Å; Y68-S71 PolarHBondContact O-N 3.25Å; Y68-L72 WeakPolarHBondContact O-CG 3.37Å; Y68-L72 PolarHBondContact O-N 3.46Å; Y68-N212 WeakPolarHBondContact CD2-O 3.41Å; Y68-N212 HydrophobicContact CE2-CB 3.92Å; Y68-N212 VanDerWaalsContact CE2-O 3.24Å; Y68-N212 WeakPolarHBondContact CE2-O 3.49Å; Y68-M216 PolarHBondContact N-O 3.34Å; Y68-Y281 AromaticContact CD1-CD1 3.52Å; Y68-Y281 HydrophobicContact CD1-CD1 3.52Å; Y68-Y281 AromaticContact CD1-CD2 3.75Å; Y68-Y281 HydrophobicContact CD1-CD2 3.75Å; Y68-Y281 AromaticContact CD1-CE1 3.85Å; Y68-Y281 HydrophobicContact CD1-CE1 3.85Å; Y68-Y281 HydrophobicContact CD1-CE2 4.04Å; Y68-Y281 AromaticContact CD1-CG 3.48Å; Y68-Y281 HydrophobicContact CD1-CG 3.48Å; Y68-Y281 VanDerWaalsContact CD1-CG 3.48Å; Y68-Y281 AromaticContact CE1-CD1 3.54Å; Y68-Y281 HydrophobicContact CE1-CD1 3.54Å; Y68-Y281 HydrophobicContact CE1-CE1 4.06Å; Y68-Y281 AromaticContact CE1-CG 3.84Å; Y68-Y281 HydrophobicContact CE1-CG 3.84Å; Y68-Y281 HydrophobicContact CG-CD1 4.43Å; Y68-Y281 HydrophobicContact CG-CD2 4.01Å; Y68-Y281 AromaticContact CG-CG 3.96Å; Y68-Y281 HydrophobicContact CG-CG 3.96Å; Y68-L284 PolarHBondContact OH-O 3.23Å; Y68-P285 WeakPolarHBondContact OH-CA 3.34Å; Y68-I286 HydrophobicContact CD1-CG1 4.11Å; Y68-I286 HydrophobicContact CE1-CB 4.41Å; Y68-I286 HydrophobicContact CE1-CD1 4.29Å; Y68-I286 HydrophobicContact CE1-CG1 3.37Å; Y68-I286 HydrophobicContact CE2-CD1 4.4Å; Y68-I286 HydrophobicContact CE2-CG1 3.9Å; Y68-I286 WeakPolarHBondContact OH-CG1 3.44Å; Y68-I286 PolarHBondContact OH-N 3.16Å; Y68-I289 HydrophobicContact CE1-CD1 4.29Å
69	G	94.8	Very high	95.2	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-64.2	-47.6	-178.7	0	0	0	0	0	111.8	S71 L72 V73 M216 F217	G69-S71 VanDerWaalsContact C-N 3.32Å; G69-S71 PolarHBondContact O-N 2.88Å; G69-L72 PolarHBondContact O-N 2.92Å; G69-V73 WeakPolarHBondContact O-CG2 3.47Å; G69-V73 PolarHBondContact O-N 3.1Å; G69-V73 VanDerWaalsContact O-N 3.1Å; G69-M216 VanDerWaalsContact CA-CE 3.44Å; G69-M216 WeakPolarHBondContact CA-O 3.46Å; G69-M216 PolarHBondContact N-O 2.84Å; G69-F217 VanDerWaalsContact C-CE1 3.4Å
70	L	96	Very high	95.1	Very high	28 Å²	28	24.2 Å²	24.2	15%	0.147	14%	0.136	C	C	.	.	H	α-helix	trans	-66.2	-36.5	175.4	-175.2	60.7	0	0	0	111.3	S67 L72 V73 V74 S221	S67-L70 VanDerWaalsContact OG-CB 3.22Å; S67-L70 WeakPolarHBondContact OG-CB 3.48Å; S67-L70 PolarHBondContact OG-N 3.39Å; S67-L70 VanDerWaalsContact OG-N 3.13Å; L70-L72 PolarHBondContact O-N 3.41Å; L70-V73 WeakPolarHBondContact O-CB 3.36Å; L70-V73 PolarHBondContact O-N 3.26Å; L70-V74 HydrophobicContact CG-CG2 4.49Å; L70-V74 VanDerWaalsContact O-CG2 3.32Å; L70-V74 WeakPolarHBondContact O-CG2 3.41Å; L70-V74 PolarHBondContact O-N 2.93Å; L70-S221 WeakPolarHBondContact CD2-O 3.23Å
71	S	96.6	Very high	95.1	Very high	0 Å²	0	24.7 Å²	24.7	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-57.7	-49.7	174.2	178.2	0	0	0	0	112.1	V61 S65 S67 Y68 G69 V73 V74 W75 Y281	V61-S71 VanDerWaalsContact CG1-OG 3.23Å; V61-S71 WeakPolarHBondContact CG1-OG 3.28Å; S65-S71 WeakPolarHBondContact OG-CB 3.49Å; S67-S71 WeakPolarHBondContact O-CB 3.45Å; S67-S71 PolarHBondContact O-N 2.92Å; S67-S71 VanDerWaalsContact O-N 3.08Å; Y68-S71 WeakPolarHBondContact O-CB 3.49Å; Y68-S71 PolarHBondContact O-N 3.25Å; G69-S71 VanDerWaalsContact C-N 3.32Å; G69-S71 PolarHBondContact O-N 2.88Å; S71-V73 VanDerWaalsContact C-N 3.29Å; S71-V73 PolarHBondContact O-N 2.91Å; S71-V74 WeakPolarHBondContact O-CB 3.26Å; S71-V74 PolarHBondContact O-N 2.98Å; S71-V74 VanDerWaalsContact O-N 3.1Å; S71-W75 PolarHBondContact O-N 3.34Å; S71-Y281 WeakPolarHBondContact CB-OH 3.43Å; S71-Y281 PolarHBondContact OG-OH 3.12Å
72	L	96.5	Very high	95	Very high	23 Å²	23	24.7 Å²	24.7	12%	0.12	14%	0.138	C	C	.	.	H	α-helix	trans	-62.9	-36	178.7	-68	175.7	0	0	0	112.3	Y68 G69 L70 W75 T76 M216 N277 V278 Y281	Y68-L72 WeakPolarHBondContact O-CG 3.37Å; Y68-L72 PolarHBondContact O-N 3.46Å; G69-L72 PolarHBondContact O-N 2.92Å; L70-L72 PolarHBondContact O-N 3.41Å; L72-W75 PolarHBondContact O-N 2.9Å; L72-T76 WeakPolarHBondContact O-CB 3.37Å; L72-T76 PolarHBondContact O-N 3.01Å; L72-T76 PolarHBondContact O-OG1 3.01Å; L72-M216 HydrophobicContact CD1-CE 4.28Å; L72-N277 HydrophobicContact CD2-CB 3.85Å; L72-V278 HydrophobicContact CD1-CG2 4.06Å; L72-V278 HydrophobicContact CD2-CG2 3.92Å; L72-Y281 HydrophobicContact CD2-CD2 4.23Å; L72-Y281 HydrophobicContact CD2-CE2 3.94Å; L72-Y281 HydrophobicContact CG-CD2 4.27Å; L72-Y281 HydrophobicContact CG-CE2 4.03Å
73	V	96.6	Very high	94.8	Very high	59 Å²	59	26.5 Å²	26.5	36%	0.358	15%	0.148	S	C	.	.	H	α-helix	trans	-62.7	-45.7	172.4	171	0	0	0	0	110.6	G69 L70 S71 W75 T76 I77 F217	G69-V73 WeakPolarHBondContact O-CG2 3.47Å; G69-V73 PolarHBondContact O-N 3.1Å; G69-V73 VanDerWaalsContact O-N 3.1Å; L70-V73 WeakPolarHBondContact O-CB 3.36Å; L70-V73 PolarHBondContact O-N 3.26Å; S71-V73 VanDerWaalsContact C-N 3.29Å; S71-V73 PolarHBondContact O-N 2.91Å; V73-W75 PolarHBondContact O-N 3.14Å; V73-T76 WeakPolarHBondContact O-CB 3.37Å; V73-T76 PolarHBondContact O-N 2.82Å; V73-T76 VanDerWaalsContact O-N 3.16Å; V73-I77 HydrophobicContact CG1-CD1 3.62Å; V73-I77 HydrophobicContact CG1-CG1 4.24Å; V73-I77 WeakPolarHBondContact O-CG1 3.47Å; V73-I77 PolarHBondContact O-N 3.16Å; V73-F217 HydrophobicContact CG2-CE1 4.33Å
74	V	96.8	Very high	94.7	Very high	3 Å²	3	25.1 Å²	25.1	2%	0.018	14%	0.14	C	C	.	.	H	α-helix	trans	-59.9	-44	176.7	169.1	0	0	0	0	111.4	V61 L70 S71 T76 I77 G78 A230 L231 A234	V61-V74 HydrophobicContact CG1-CB 4.08Å; V61-V74 HydrophobicContact CG1-CG1 3.89Å; L70-V74 HydrophobicContact CG-CG2 4.49Å; L70-V74 VanDerWaalsContact O-CG2 3.32Å; L70-V74 WeakPolarHBondContact O-CG2 3.41Å; L70-V74 PolarHBondContact O-N 2.93Å; S71-V74 WeakPolarHBondContact O-CB 3.26Å; S71-V74 PolarHBondContact O-N 2.98Å; S71-V74 VanDerWaalsContact O-N 3.1Å; V74-T76 VanDerWaalsContact C-N 3.31Å; V74-T76 PolarHBondContact O-N 3.39Å; V74-I77 PolarHBondContact O-N 2.93Å; V74-G78 PolarHBondContact O-N 3.28Å; V74-A230 HydrophobicContact CG1-CB 4.01Å; V74-A230 HydrophobicContact CG2-CB 4.2Å; V74-L231 HydrophobicContact CG1-CD2 3.97Å; V74-L231 HydrophobicContact CG1-CG 4.13Å; V74-A234 HydrophobicContact CG1-CB 4.01Å
75	W	97.1	Very high	94.6	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-61.2	-38.9	174.8	-82.2	103.9	0	0	0	113	I54 P58 V61 S71 L72 V73 G79 A234 S237 Y238 Y273 I274 N277	I54-W75 HydrophobicContact CD1-CH2 3.5Å; I54-W75 VanDerWaalsContact CD1-CH2 3.5Å; I54-W75 HydrophobicContact CD1-CZ2 4.06Å; I54-W75 HydrophobicContact CD1-CZ3 3.93Å; P58-W75 HydrophobicContact CG-CZ2 4.17Å; V61-W75 HydrophobicContact CG2-CZ2 4.24Å; S71-W75 PolarHBondContact O-N 3.34Å; L72-W75 PolarHBondContact O-N 2.9Å; V73-W75 PolarHBondContact O-N 3.14Å; W75-G79 PolarHBondContact O-N 3.17Å; W75-G79 VanDerWaalsContact O-N 3.1Å; W75-A234 HydrophobicContact CD2-CB 4.33Å; W75-A234 HydrophobicContact CE3-CB 4.31Å; W75-S237 WeakPolarHBondContact CH2-OG 3.26Å; W75-Y238 HydrophobicContact CE3-CD2 4.49Å; W75-Y238 AromaticContact CE3-CE2 3.69Å; W75-Y238 HydrophobicContact CE3-CE2 3.69Å; W75-Y238 HydrophobicContact CZ3-CE2 4.1Å; W75-Y238 WeakPolarHBondContact O-CE2 3.49Å; W75-Y238 PolarHBondContact O-OH 2.74Å; W75-Y273 AromaticContact CE3-CD2 4Å; W75-Y273 HydrophobicContact CE3-CD2 4Å; W75-Y273 HydrophobicContact CE3-CG 4.33Å; W75-Y273 AromaticContact CZ3-CD2 3.48Å; W75-Y273 HydrophobicContact CZ3-CD2 3.48Å; W75-Y273 VanDerWaalsContact CZ3-CD2 3.48Å; W75-Y273 HydrophobicContact CZ3-CE2 4.14Å; W75-Y273 AromaticContact CZ3-CG 3.93Å; W75-Y273 HydrophobicContact CZ3-CG 3.93Å; W75-I274 HydrophobicContact CB-CG1 4.45Å; W75-N277 PolarHBondContact NE1-ND2 3.39Å; W75-N277 PolarHBondContact NE1-OD1 2.91Å
76	T	96.5	Very high	94.5	Very high	52 Å²	52	23.6 Å²	23.6	32%	0.319	13%	0.133	S	C	.	.	H	α-helix	trans	-68.9	-47.9	178	-55.9	0	0	0	0	111	L72 V73 V74 G78 G79 I80 I274	L72-T76 WeakPolarHBondContact O-CB 3.37Å; L72-T76 PolarHBondContact O-N 3.01Å; L72-T76 PolarHBondContact O-OG1 3.01Å; V73-T76 WeakPolarHBondContact O-CB 3.37Å; V73-T76 PolarHBondContact O-N 2.82Å; V73-T76 VanDerWaalsContact O-N 3.16Å; V74-T76 VanDerWaalsContact C-N 3.31Å; V74-T76 PolarHBondContact O-N 3.39Å; T76-G78 VanDerWaalsContact C-N 3.32Å; T76-G78 PolarHBondContact O-N 3.17Å; T76-G79 PolarHBondContact O-N 3.41Å; T76-I80 HydrophobicContact CG2-CD1 4.09Å; T76-I80 WeakPolarHBondContact O-CG1 3.17Å; T76-I80 PolarHBondContact O-N 3.17Å; T76-I274 HydrophobicContact CG2-CD1 4.5Å; T76-I274 WeakPolarHBondContact OG1-CD1 3.24Å
77	I	95.3	Very high	94.4	Very high	84 Å²	84	23.1 Å²	23.1	43%	0.431	12%	0.124	S	C	.	.	H	α-helix	trans	-61.3	-42.5	176.8	-68.2	172.4	0	0	0	110.4	V73 V74 G79 I80 F81 L231	V73-I77 HydrophobicContact CG1-CD1 3.62Å; V73-I77 HydrophobicContact CG1-CG1 4.24Å; V73-I77 WeakPolarHBondContact O-CG1 3.47Å; V73-I77 PolarHBondContact O-N 3.16Å; V74-I77 PolarHBondContact O-N 2.93Å; I77-G79 VanDerWaalsContact C-N 3.32Å; I77-G79 PolarHBondContact O-N 2.96Å; I77-I80 PolarHBondContact O-N 2.92Å; I77-F81 VanDerWaalsContact O-CB 3.26Å; I77-F81 WeakPolarHBondContact O-CB 3.4Å; I77-F81 PolarHBondContact O-N 3.42Å; I77-L231 HydrophobicContact CB-CD2 4.35Å; I77-L231 HydrophobicContact CG2-CD2 3.94Å
78	G	94.8	Very high	94.3	Very high	0 Å²	0	23 Å²	23	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-60.3	-39.7	176	0	0	0	0	0	113.1	V74 T76 S82	V74-G78 PolarHBondContact O-N 3.28Å; T76-G78 VanDerWaalsContact C-N 3.32Å; T76-G78 PolarHBondContact O-N 3.17Å; G78-S82 WeakPolarHBondContact O-CB 3.48Å; G78-S82 PolarHBondContact O-N 2.92Å; G78-S82 PolarHBondContact O-OG 3.42Å
79	G	94.3	Very high	94.2	Very high	1 Å²	1	22.5 Å²	22.5	1%	0.01	12%	0.121	C	C	.	.	H	α-helix	trans	-65.1	-49	174.4	0	0	0	0	0	112.4	W75 T76 I77 F81 S82 V83	W75-G79 PolarHBondContact O-N 3.17Å; W75-G79 VanDerWaalsContact O-N 3.1Å; T76-G79 PolarHBondContact O-N 3.41Å; I77-G79 VanDerWaalsContact C-N 3.32Å; I77-G79 PolarHBondContact O-N 2.96Å; G79-F81 PolarHBondContact O-N 2.75Å; G79-S82 PolarHBondContact O-N 3.4Å; G79-V83 WeakPolarHBondContact O-CG2 2.98Å; G79-V83 PolarHBondContact O-N 3.21Å
80	I	93.5	Very high	94	Very high	89 Å²	89	22.5 Å²	22.5	46%	0.456	12%	0.121	S	C	.	.	H	α-helix	trans	-60.5	-45.6	177.5	-66.3	168.4	0	0	0	111	T76 I77 S82 V83 F84	T76-I80 HydrophobicContact CG2-CD1 4.09Å; T76-I80 WeakPolarHBondContact O-CG1 3.17Å; T76-I80 PolarHBondContact O-N 3.17Å; I77-I80 PolarHBondContact O-N 2.92Å; I80-S82 VanDerWaalsContact C-N 3.3Å; I80-S82 PolarHBondContact O-N 3.32Å; I80-V83 WeakPolarHBondContact O-CB 3.36Å; I80-V83 PolarHBondContact O-N 3.46Å; I80-F84 HydrophobicContact CG2-CZ 4.44Å; I80-F84 PolarHBondContact O-N 2.89Å; I80-F84 VanDerWaalsContact O-N 3.15Å
81	F	93.2	Very high	93.8	Very high	10 Å²	10	21.2 Å²	21.2	4%	0.044	11%	0.114	C	C	.	.	H	α-helix	trans	-58.5	-43.6	176.2	172.4	-94.9	0	0	0	111.6	I77 G79 V83 F84 G85 L235 W389 F423 L426 T427 L430	I77-F81 VanDerWaalsContact O-CB 3.26Å; I77-F81 WeakPolarHBondContact O-CB 3.4Å; I77-F81 PolarHBondContact O-N 3.42Å; G79-F81 PolarHBondContact O-N 2.75Å; F81-V83 VanDerWaalsContact C-N 3.35Å; F81-V83 PolarHBondContact O-N 2.81Å; F81-F84 PolarHBondContact O-N 2.73Å; F81-G85 PolarHBondContact O-N 3.24Å; F81-L235 HydrophobicContact CD1-CD1 3.98Å; F81-L235 HydrophobicContact CD1-CD2 3.42Å; F81-L235 VanDerWaalsContact CD1-CD2 3.42Å; F81-L235 HydrophobicContact CD1-CG 4.37Å; F81-L235 HydrophobicContact CE1-CD1 3.86Å; F81-L235 HydrophobicContact CE1-CD2 3.95Å; F81-L235 HydrophobicContact CG-CD2 4.37Å; F81-W389 HydrophobicContact CD1-CH2 4.35Å; F81-W389 HydrophobicContact CD1-CZ3 4.39Å; F81-W389 HydrophobicContact CE1-CD2 4.14Å; F81-W389 AromaticContact CE1-CE3 3.65Å; F81-W389 HydrophobicContact CE1-CE3 3.65Å; F81-W389 AromaticContact CE1-CH2 3.7Å; F81-W389 HydrophobicContact CE1-CH2 3.7Å; F81-W389 HydrophobicContact CE1-CZ2 4.19Å; F81-W389 AromaticContact CE1-CZ3 3.4Å; F81-W389 HydrophobicContact CE1-CZ3 3.4Å; F81-W389 VanDerWaalsContact CE1-CZ3 3.4Å; F81-W389 AromaticContact CZ-CE3 3.94Å; F81-W389 HydrophobicContact CZ-CE3 3.94Å; F81-W389 HydrophobicContact CZ-CZ3 4.04Å; F81-F423 HydrophobicContact CD1-CE2 4.18Å; F81-F423 HydrophobicContact CD2-CD2 4.15Å; F81-F423 HydrophobicContact CD2-CE2 4.04Å; F81-F423 AromaticContact CE1-CE2 3.73Å; F81-F423 HydrophobicContact CE1-CE2 3.73Å; F81-F423 HydrophobicContact CE1-CZ 4.01Å; F81-F423 AromaticContact CE2-CD2 3.78Å; F81-F423 HydrophobicContact CE2-CD2 3.78Å; F81-F423 AromaticContact CE2-CE2 3.51Å; F81-F423 HydrophobicContact CE2-CE2 3.51Å; F81-F423 HydrophobicContact CE2-CG 4.48Å; F81-F423 HydrophobicContact CE2-CZ 4.01Å; F81-F423 HydrophobicContact CG-CE2 4.36Å; F81-F423 HydrophobicContact CZ-CD2 4.11Å; F81-F423 HydrophobicContact CZ-CE1 4.35Å; F81-F423 AromaticContact CZ-CE2 3.36Å; F81-F423 HydrophobicContact CZ-CE2 3.36Å; F81-F423 AromaticContact CZ-CZ 3.51Å; F81-F423 HydrophobicContact CZ-CZ 3.51Å; F81-L426 HydrophobicContact CD2-CB 3.63Å; F81-L426 HydrophobicContact CD2-CD1 3.7Å; F81-L426 HydrophobicContact CD2-CG 4.27Å; F81-L426 HydrophobicContact CE2-CB 3.45Å; F81-L426 VanDerWaalsContact CE2-CB 3.45Å; F81-L426 HydrophobicContact CE2-CD1 4.35Å; F81-T427 HydrophobicContact CE2-CG2 4.23Å; F81-T427 HydrophobicContact CZ-CG2 3.84Å; F81-L430 HydrophobicContact CE1-CD1 3.83Å; F81-L430 HydrophobicContact CE2-CD1 4.01Å; F81-L430 HydrophobicContact CZ-CD1 3.47Å; F81-L430 VanDerWaalsContact CZ-CD1 3.47Å
82	S	92.9	Very high	93.5	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-67.2	-34.5	178.8	-57.7	0	0	0	0	112.3	G78 G79 I80 G85 A86 Y238	G78-S82 WeakPolarHBondContact O-CB 3.48Å; G78-S82 PolarHBondContact O-N 2.92Å; G78-S82 PolarHBondContact O-OG 3.42Å; G79-S82 PolarHBondContact O-N 3.4Å; I80-S82 VanDerWaalsContact C-N 3.3Å; I80-S82 PolarHBondContact O-N 3.32Å; S82-G85 PolarHBondContact O-N 2.9Å; S82-A86 VanDerWaalsContact O-CB 3.28Å; S82-A86 WeakPolarHBondContact O-CB 3.47Å; S82-A86 PolarHBondContact O-N 2.84Å; S82-Y238 VanDerWaalsContact OG-CB 3.31Å; S82-Y238 WeakPolarHBondContact OG-CB 3.39Å
83	V	91.8	Very high	93.1	Very high	39 Å²	39	20.3 Å²	20.3	24%	0.236	11%	0.11	C	C	.	.	H	α-helix	trans	-60.2	-46.5	172.8	170.8	0	0	0	0	110.6	G79 I80 F81 A86 L87 M266	G79-V83 WeakPolarHBondContact O-CG2 2.98Å; G79-V83 PolarHBondContact O-N 3.21Å; I80-V83 WeakPolarHBondContact O-CB 3.36Å; I80-V83 PolarHBondContact O-N 3.46Å; F81-V83 VanDerWaalsContact C-N 3.35Å; F81-V83 PolarHBondContact O-N 2.81Å; V83-A86 PolarHBondContact O-N 3.45Å; V83-L87 HydrophobicContact CG1-CD1 3.92Å; V83-L87 HydrophobicContact CG1-CG 4.38Å; V83-L87 WeakPolarHBondContact O-CB 3.27Å; V83-L87 VanDerWaalsContact O-CG 3.28Å; V83-L87 WeakPolarHBondContact O-CG 3.49Å; V83-L87 PolarHBondContact O-N 3.28Å; V83-M266 HydrophobicContact CG2-CB 3.63Å; V83-M266 HydrophobicContact CG2-CE 4.34Å; V83-M266 HydrophobicContact CG2-CG 4.34Å
84	F	92	Very high	92.8	Very high	49 Å²	49	17.9 Å²	17.9	22%	0.215	10%	0.095	C	C	.	.	H	α-helix	trans	-62.3	-44.1	177.6	-72.3	-5.9	0	0	0	111.9	I80 F81 L87 C88 Y419 I422 F423	I80-F84 HydrophobicContact CG2-CZ 4.44Å; I80-F84 PolarHBondContact O-N 2.89Å; I80-F84 VanDerWaalsContact O-N 3.15Å; F81-F84 PolarHBondContact O-N 2.73Å; F84-L87 PolarHBondContact O-N 2.91Å; F84-C88 PolarHBondContact O-N 3.06Å; F84-C88 PolarHBondContact O-SG 3.02Å; F84-C88 VanDerWaalsContact O-SG 3.33Å; F84-Y419 AromaticContact CD1-CD1 3.64Å; F84-Y419 HydrophobicContact CD1-CD1 3.64Å; F84-Y419 AromaticContact CD1-CE1 3.93Å; F84-Y419 HydrophobicContact CD1-CE1 3.93Å; F84-Y419 AromaticContact CE1-CD1 3.75Å; F84-Y419 HydrophobicContact CE1-CD1 3.75Å; F84-Y419 AromaticContact CE1-CE1 3.64Å; F84-Y419 HydrophobicContact CE1-CE1 3.64Å; F84-Y419 HydrophobicContact CG-CD1 4.25Å; F84-Y419 HydrophobicContact CZ-CD1 4.43Å; F84-Y419 HydrophobicContact CZ-CE1 4.42Å; F84-I422 HydrophobicContact CD2-CG2 4.02Å; F84-I422 HydrophobicContact CE2-CG2 3.96Å; F84-F423 HydrophobicContact CB-CD2 4.19Å
85	G	91.9	Very high	92.4	Very high	0 Å²	0	18.7 Å²	18.7	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-59.5	-48.3	175.7	0	0	0	0	0	112.5	F81 S82 L87 C88 Y89	F81-G85 PolarHBondContact O-N 3.24Å; S82-G85 PolarHBondContact O-N 2.9Å; G85-L87 PolarHBondContact O-N 3.42Å; G85-C88 PolarHBondContact O-N 3.2Å; G85-Y89 WeakPolarHBondContact O-CD2 3.42Å; G85-Y89 PolarHBondContact O-N 2.86Å
86	A	91.8	Very high	92	Very high	0 Å²	0	18.9 Å²	18.9	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-64.5	-40.2	-178.9	0	0	0	0	0	112.3	S82 V83 Y89 A90 W241 I262 M266	S82-A86 VanDerWaalsContact O-CB 3.28Å; S82-A86 WeakPolarHBondContact O-CB 3.47Å; S82-A86 PolarHBondContact O-N 2.84Å; V83-A86 PolarHBondContact O-N 3.45Å; A86-Y89 PolarHBondContact O-N 2.94Å; A86-A90 PolarHBondContact O-N 2.98Å; A86-W241 VanDerWaalsContact CA-CE3 3.46Å; A86-W241 HydrophobicContact CB-CB 4.24Å; A86-W241 HydrophobicContact CB-CD2 3.8Å; A86-W241 HydrophobicContact CB-CE3 3.63Å; A86-W241 HydrophobicContact CB-CG 4.07Å; A86-W241 HydrophobicContact CB-CZ3 4.3Å; A86-I262 HydrophobicContact CB-CD1 4.48Å; A86-I262 HydrophobicContact CB-CG2 3.43Å; A86-I262 VanDerWaalsContact CB-CG2 3.43Å; A86-M266 HydrophobicContact CB-CG 4.22Å; A86-M266 HydrophobicContact CB-SD 4.28Å
87	L	91.4	Very high	91.2	Very high	35 Å²	35	20 Å²	20	18%	0.183	11%	0.108	C	C	.	.	H	α-helix	trans	-62.3	-46.9	174	-72.1	173.5	0	0	0	111.5	V83 F84 G85 Y89 A90 E91 L415 Y419	V83-L87 HydrophobicContact CG1-CD1 3.92Å; V83-L87 HydrophobicContact CG1-CG 4.38Å; V83-L87 WeakPolarHBondContact O-CB 3.27Å; V83-L87 VanDerWaalsContact O-CG 3.28Å; V83-L87 WeakPolarHBondContact O-CG 3.49Å; V83-L87 PolarHBondContact O-N 3.28Å; F84-L87 PolarHBondContact O-N 2.91Å; G85-L87 PolarHBondContact O-N 3.42Å; L87-Y89 VanDerWaalsContact C-N 3.28Å; L87-Y89 PolarHBondContact O-N 3.23Å; L87-A90 VanDerWaalsContact O-CB 3.29Å; L87-A90 WeakPolarHBondContact O-CB 3.18Å; L87-A90 PolarHBondContact O-N 3.23Å; L87-E91 PolarHBondContact O-N 2.88Å; L87-E91 VanDerWaalsContact O-N 3.15Å; L87-L415 HydrophobicContact CB-CD1 3.8Å; L87-L415 WeakPolarHBondContact O-CD1 3.3Å; L87-Y419 HydrophobicContact CD1-CE1 4.42Å
88	C	92.9	Very high	90.3	Very high	0 Å²	0	20.9 Å²	20.9	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-59.2	-40.4	175.9	-70.4	0	0	0	0	112.2	F84 G85 E91 L92 I396 Q399 P420	F84-C88 PolarHBondContact O-N 3.06Å; F84-C88 PolarHBondContact O-SG 3.02Å; F84-C88 VanDerWaalsContact O-SG 3.33Å; G85-C88 PolarHBondContact O-N 3.2Å; C88-E91 PolarHBondContact O-N 3.34Å; C88-L92 PolarHBondContact O-N 3.28Å; C88-L92 VanDerWaalsContact O-N 3.09Å; C88-I396 HydrophobicContact CB-CD1 3.7Å; C88-I396 HydrophobicContact CB-CG1 3.86Å; C88-I396 HydrophobicContact CB-CG2 4.32Å; C88-Q399 PolarHBondContact O-OE1 3.37Å; C88-P420 VanDerWaalsContact SG-CA 3.59Å
89	Y	91.6	Very high	89.2	Confident	0 Å²	0	22.2 Å²	22.2	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-68.9	-30.6	173.8	-94.4	-118.5	0	0	0	113.5	G85 A86 L87 E91 L92 G93 S102 Y105 W241 D242 N245 V392 S395 I396	G85-Y89 WeakPolarHBondContact O-CD2 3.42Å; G85-Y89 PolarHBondContact O-N 2.86Å; A86-Y89 PolarHBondContact O-N 2.94Å; L87-Y89 VanDerWaalsContact C-N 3.28Å; L87-Y89 PolarHBondContact O-N 3.23Å; Y89-E91 VanDerWaalsContact C-N 3.3Å; Y89-E91 PolarHBondContact O-N 3.42Å; Y89-L92 PolarHBondContact O-N 2.9Å; Y89-G93 PolarHBondContact O-N 3.44Å; Y89-S102 PolarHBondContact OH-OG 3.22Å; Y89-Y105 HydrophobicContact CD1-CD2 4.42Å; Y89-Y105 AromaticContact CD1-CE2 3.76Å; Y89-Y105 HydrophobicContact CD1-CE2 3.76Å; Y89-Y105 HydrophobicContact CE1-CD2 4.17Å; Y89-Y105 AromaticContact CE1-CE2 3.89Å; Y89-Y105 HydrophobicContact CE1-CE2 3.89Å; Y89-Y105 HydrophobicContact CG-CE2 4.48Å; Y89-W241 HydrophobicContact CD1-CH2 4.38Å; Y89-W241 AromaticContact CD1-CZ3 3.81Å; Y89-W241 HydrophobicContact CD1-CZ3 3.81Å; Y89-W241 AromaticContact CD2-CH2 3.64Å; Y89-W241 HydrophobicContact CD2-CH2 3.64Å; Y89-W241 AromaticContact CD2-CZ3 3.65Å; Y89-W241 HydrophobicContact CD2-CZ3 3.65Å; Y89-W241 HydrophobicContact CE1-CZ3 4.38Å; Y89-W241 AromaticContact CE2-CH2 3.91Å; Y89-W241 HydrophobicContact CE2-CH2 3.91Å; Y89-W241 HydrophobicContact CE2-CZ3 4.25Å; Y89-W241 AromaticContact CG-CH2 3.92Å; Y89-W241 HydrophobicContact CG-CH2 3.92Å; Y89-W241 AromaticContact CG-CZ3 3.42Å; Y89-W241 HydrophobicContact CG-CZ3 3.42Å; Y89-W241 VanDerWaalsContact CG-CZ3 3.42Å; Y89-D242 HydrophobicContact CD1-CB 4.05Å; Y89-D242 HydrophobicContact CE1-CB 4.16Å; Y89-N245 PolarHBondContact O-ND2 3.42Å; Y89-V392 HydrophobicContact CE2-CG1 3.75Å; Y89-V392 WeakPolarHBondContact OH-CA 3.44Å; Y89-S395 VanDerWaalsContact OH-CB 3.3Å; Y89-S395 WeakPolarHBondContact OH-CB 3.26Å; Y89-S395 PolarHBondContact OH-OG 2.81Å; Y89-I396 HydrophobicContact CD2-CD1 3.92Å; Y89-I396 HydrophobicContact CD2-CG1 4.03Å; Y89-I396 HydrophobicContact CE2-CD1 3.86Å; Y89-I396 HydrophobicContact CE2-CG1 3.86Å
90	A	90.7	Very high	88.2	Confident	0 Å²	0	22.3 Å²	22.3	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-61.3	-42.4	172.6	0	0	0	0	0	110.4	A86 L87 G93 T94 P259 I262 L413	A86-A90 PolarHBondContact O-N 2.98Å; L87-A90 VanDerWaalsContact O-CB 3.29Å; L87-A90 WeakPolarHBondContact O-CB 3.18Å; L87-A90 PolarHBondContact O-N 3.23Å; A90-G93 PolarHBondContact O-N 2.91Å; A90-T94 VanDerWaalsContact O-CG2 3.3Å; A90-T94 WeakPolarHBondContact O-CG2 3.33Å; A90-T94 PolarHBondContact O-N 3.13Å; A90-T94 PolarHBondContact O-OG1 2.99Å; A90-P259 HydrophobicContact CB-CB 4.42Å; A90-P259 HydrophobicContact CB-CG 4.32Å; A90-I262 HydrophobicContact CB-CD1 3.78Å; A90-L413 HydrophobicContact CB-CD2 3.8Å
91	E	91.6	Very high	87.7	Confident	1 Å²	1	18.1 Å²	18.1	1%	0.005	10%	0.097	C	C	.	.	H	α-helix	trans	-63	-47.6	173.9	171.8	170	152.1	0	0	111.7	L87 C88 Y89 G93 T94 T95 Q399 R403 L413 L415	L87-E91 PolarHBondContact O-N 2.88Å; L87-E91 VanDerWaalsContact O-N 3.15Å; C88-E91 PolarHBondContact O-N 3.34Å; Y89-E91 VanDerWaalsContact C-N 3.3Å; Y89-E91 PolarHBondContact O-N 3.42Å; E91-G93 VanDerWaalsContact C-N 3.34Å; E91-G93 PolarHBondContact O-N 3.47Å; E91-T94 PolarHBondContact O-N 2.89Å; E91-T94 PolarHBondContact O-OG1 3.49Å; E91-T95 WeakPolarHBondContact O-CB 3.2Å; E91-T95 PolarHBondContact O-N 3.2Å; E91-T95 PolarHBondContact O-OG1 3.34Å; E91-Q399 PolarHBondContact OE1-NE2 2.81Å; E91-Q399 PolarHBondContact OE2-NE2 3.38Å; E91-R403 IonicContact OE1-CZ 2.7Å; E91-R403 IonicContact OE1-NE 2.7Å; E91-R403 PolarHBondContact OE1-NE 3.08Å; E91-R403 IonicContact OE1-NH2 3.76Å; E91-R403 PolarHBondContact OE1-NH2 3.43Å; E91-R403 IonicContact OE2-CZ 2.84Å; E91-R403 IonicContact OE2-NH2 3.79Å; E91-R403 PolarHBondContact OE2-NH2 3.22Å; E91-L413 HydrophobicContact CB-CD2 4.19Å; E91-L413 WeakPolarHBondContact CG-O 3.45Å; E91-L415 HydrophobicContact CB-CD1 4.28Å; E91-L415 WeakPolarHBondContact OE2-CB 3.49Å; E91-L415 PolarHBondContact OE2-N 2.99Å
92	L	91.3	Very high	87.4	Confident	5 Å²	5	17.6 Å²	17.6	3%	0.026	10%	0.095	C	C	.	.	H	α-helix	trans	-59.7	-43.6	177.1	-77.1	171.8	0	0	0	112.2	C88 Y89 T94 T95 I96 Y105 Q399	C88-L92 PolarHBondContact O-N 3.28Å; C88-L92 VanDerWaalsContact O-N 3.09Å; Y89-L92 PolarHBondContact O-N 2.9Å; L92-T94 PolarHBondContact O-N 3.31Å; L92-T95 PolarHBondContact O-N 3.08Å; L92-I96 HydrophobicContact CD2-CD1 4.4Å; L92-I96 PolarHBondContact O-N 3.26Å; L92-Y105 HydrophobicContact CB-CD1 4.28Å; L92-Y105 HydrophobicContact CB-CD2 3.92Å; L92-Y105 HydrophobicContact CB-CE1 4.15Å; L92-Y105 HydrophobicContact CB-CE2 3.75Å; L92-Y105 HydrophobicContact CB-CG 4.18Å; L92-Y105 HydrophobicContact CD1-CD2 3.81Å; L92-Y105 HydrophobicContact CD1-CE2 4.29Å; L92-Y105 HydrophobicContact CD1-CG 4.26Å; L92-Y105 HydrophobicContact CG-CD2 4.41Å; L92-Q399 HydrophobicContact CD1-CB 4.18Å; L92-Q399 HydrophobicContact CD2-CB 3.72Å; L92-Q399 HydrophobicContact CD2-CG 3.91Å; L92-Q399 HydrophobicContact CG-CB 4Å; L92-Q399 HydrophobicContact CG-CG 4.05Å
93	G	87.9	Confident	87.3	Confident	0 Å²	0	17.8 Å²	17.8	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-69.1	-31.6	-180	0	0	0	0	0	114	Y89 A90 E91 Y105	Y89-G93 PolarHBondContact O-N 3.44Å; A90-G93 PolarHBondContact O-N 2.91Å; E91-G93 VanDerWaalsContact C-N 3.34Å; E91-G93 PolarHBondContact O-N 3.47Å; G93-Y105 WeakPolarHBondContact CA-OH 3.28Å; G93-Y105 PolarHBondContact N-OH 3.21Å
94	T	89.3	Confident	87.1	Confident	8 Å²	8	16.1 Å²	16.1	5%	0.049	9%	0.086	C	C	.	.	H	α-helix	trans	-76.7	-23.7	172.4	56.8	0	0	0	0	113	A90 E91 L92 L258 P259 L413	A90-T94 VanDerWaalsContact O-CG2 3.3Å; A90-T94 WeakPolarHBondContact O-CG2 3.33Å; A90-T94 PolarHBondContact O-N 3.13Å; A90-T94 PolarHBondContact O-OG1 2.99Å; E91-T94 PolarHBondContact O-N 2.89Å; E91-T94 PolarHBondContact O-OG1 3.49Å; L92-T94 PolarHBondContact O-N 3.31Å; T94-L258 HydrophobicContact CG2-CD2 4.29Å; T94-P259 HydrophobicContact CG2-CG 4.49Å; T94-L413 HydrophobicContact CG2-CB 4.36Å; T94-L413 WeakPolarHBondContact OG1-CB 3.46Å
95	T	89.6	Confident	87.1	Confident	20 Å²	20	13.9 Å²	13.9	12%	0.123	8%	0.076	C	C	.	.	H	α-helix	trans	-90.6	-35	179.9	-53.7	0	0	0	0	112.8	E91 L92 R409 R411	E91-T95 WeakPolarHBondContact O-CB 3.2Å; E91-T95 PolarHBondContact O-N 3.2Å; E91-T95 PolarHBondContact O-OG1 3.34Å; L92-T95 PolarHBondContact O-N 3.08Å; T95-R409 HydrophobicContact CG2-CG 4.24Å; T95-R411 HydrophobicContact CG2-CG 4.07Å
96	I	87.6	Confident	87.2	Confident	3 Å²	3	13.9 Å²	13.9	2%	0.015	8%	0.076	C	C	.	.			trans	-123.3	90.8	-179.4	-54.5	168.9	0	0	0	106.4	L92 K98 Y105 E108 L402	L92-I96 HydrophobicContact CD2-CD1 4.4Å; L92-I96 PolarHBondContact O-N 3.26Å; I96-K98 HydrophobicContact CG2-CB 4.27Å; I96-K98 HydrophobicContact CG2-CD 4.49Å; I96-K98 HydrophobicContact CG2-CG 4.41Å; I96-K98 PolarHBondContact O-N 2.9Å; I96-Y105 HydrophobicContact CB-CD1 3.9Å; I96-Y105 HydrophobicContact CB-CE1 3.99Å; I96-Y105 HydrophobicContact CD1-CD1 3.91Å; I96-Y105 HydrophobicContact CG1-CD1 4.48Å; I96-Y105 HydrophobicContact CG2-CD1 4.07Å; I96-Y105 HydrophobicContact CG2-CE1 4.33Å; I96-E108 HydrophobicContact CD1-CB 3.94Å; I96-E108 HydrophobicContact CD1-CG 3.95Å; I96-E108 HydrophobicContact CG1-CG 4.37Å; I96-L402 HydrophobicContact CD1-CD1 3.94Å
97	T	79.5	Confident	87.2	Confident	76 Å²	76	15.6 Å²	15.6	47%	0.466	9%	0.085	S	C	.	.			trans	-80	4.3	-175.2	50.3	0	0	0	0	114	E249	T97-E249 WeakPolarHBondContact O-CG 3.24Å
98	K	77.6	Confident	87.2	Confident	102 Å²	102	16.8 Å²	16.8	44%	0.443	9%	0.09	S	C	.	.			trans	-66.7	135.8	177	-64	177.1	-178.7	167.9	0	110.8	I96 A104 E108 E249	I96-K98 HydrophobicContact CG2-CB 4.27Å; I96-K98 HydrophobicContact CG2-CD 4.49Å; I96-K98 HydrophobicContact CG2-CG 4.41Å; I96-K98 PolarHBondContact O-N 2.9Å; K98-A104 HydrophobicContact CB-CB 4.24Å; K98-E108 IonicContact NZ-OE2 3.58Å; K98-E108 PolarHBondContact NZ-OE2 2.87Å; K98-E249 WeakPolarHBondContact CA-OE1 3.34Å
99	S	71.1	Confident	87.2	Confident	29 Å²	29	17.1 Å²	17.1	20%	0.203	9%	0.092	C	C	.	.	T	Hydrogen-bonded Turn	trans	-60.9	143.4	170.4	-78.3	0	0	0	0	113.2	F246 E249	S99-F246 PolarHBondContact OG-O 3.43Å; S99-E249 PolarHBondContact N-OE1 3.49Å
100	G	73.4	Confident	87.3	Confident	3 Å²	3	20.5 Å²	20.5	3%	0.031	11%	0.107	C	C	.	.	T	Hydrogen-bonded Turn	trans	122.3	-3	179.3	0	0	0	0	0	115.4	S102 Y103 F246	G100-S102 PolarHBondContact O-N 3.4Å; G100-Y103 WeakPolarHBondContact O-CB 3.42Å; G100-Y103 PolarHBondContact O-N 3.21Å; G100-Y103 VanDerWaalsContact O-N 3.1Å; G100-F246 WeakPolarHBondContact O-CE1 3.42Å
101	A	83.3	Confident	87.3	Confident	0 Å²	0	21.9 Å²	21.9	0%	0	12%	0.122	C	C	.	.	T	Hydrogen-bonded Turn	trans	44.6	-119.5	177	0	0	0	0	0	112.8	Y103 A104 Y105 N245 F246	A101-Y103 PolarHBondContact O-N 2.9Å; A101-Y103 VanDerWaalsContact O-N 3.1Å; A101-A104 PolarHBondContact O-N 3.48Å; A101-Y105 HydrophobicContact CB-CE2 4.46Å; A101-Y105 WeakPolarHBondContact O-CD1 3.42Å; A101-Y105 VanDerWaalsContact O-CD2 3.32Å; A101-Y105 WeakPolarHBondContact O-CD2 3.35Å; A101-Y105 PolarHBondContact O-N 2.98Å; A101-N245 HydrophobicContact CB-CB 3.84Å; A101-F246 HydrophobicContact CB-CD1 3.72Å; A101-F246 HydrophobicContact CB-CD2 3.61Å; A101-F246 HydrophobicContact CB-CE1 3.64Å; A101-F246 HydrophobicContact CB-CE2 3.55Å; A101-F246 HydrophobicContact CB-CG 3.72Å; A101-F246 HydrophobicContact CB-CZ 3.58Å
102	S	86.9	Confident	87.3	Confident	0 Å²	0	22.8 Å²	22.8	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-52.9	-35.9	-177.2	-48.5	0	0	0	0	113.7	Y89 G100 I106	Y89-S102 PolarHBondContact OH-OG 3.22Å; G100-S102 PolarHBondContact O-N 3.4Å; S102-I106 WeakPolarHBondContact O-CB 3.32Å; S102-I106 WeakPolarHBondContact O-CD1 3.13Å; S102-I106 VanDerWaalsContact O-CG1 3.23Å; S102-I106 WeakPolarHBondContact O-CG1 3.24Å; S102-I106 PolarHBondContact O-N 3.45Å
103	Y	89.8	Confident	87.3	Confident	3 Å²	3	26 Å²	26	1%	0.012	15%	0.145	C	C	.	.	H	α-helix	trans	-64.2	-49.2	176.9	168	-100.6	0	0	0	111.2	G100 A101 Y105 I106 L107 A115 L119 V336 E340 H342	G100-Y103 WeakPolarHBondContact O-CB 3.42Å; G100-Y103 PolarHBondContact O-N 3.21Å; G100-Y103 VanDerWaalsContact O-N 3.1Å; A101-Y103 PolarHBondContact O-N 2.9Å; A101-Y103 VanDerWaalsContact O-N 3.1Å; Y103-Y105 VanDerWaalsContact C-N 3.34Å; Y103-Y105 PolarHBondContact O-N 3.3Å; Y103-I106 PolarHBondContact O-N 3.17Å; Y103-L107 HydrophobicContact CE1-CD2 4.26Å; Y103-L107 VanDerWaalsContact O-CB 3.28Å; Y103-L107 WeakPolarHBondContact O-CB 3.46Å; Y103-L107 PolarHBondContact O-N 3.38Å; Y103-A115 HydrophobicContact CD2-CB 4.04Å; Y103-A115 VanDerWaalsContact CD2-O 3.29Å; Y103-A115 WeakPolarHBondContact CD2-O 3.47Å; Y103-A115 HydrophobicContact CE2-CB 3.73Å; Y103-A115 WeakPolarHBondContact CE2-O 3.48Å; Y103-L119 HydrophobicContact CD2-CB 3.88Å; Y103-L119 HydrophobicContact CE2-CB 3.99Å; Y103-L119 HydrophobicContact CE2-CD2 4.02Å; Y103-L119 HydrophobicContact CE2-CG 4.5Å; Y103-V336 HydrophobicContact CD1-CG1 4.16Å; Y103-V336 HydrophobicContact CE1-CG1 4.03Å; Y103-E340 HydrophobicContact CE1-CG 4.15Å; Y103-E340 WeakPolarHBondContact OH-CB 3.47Å; Y103-H342 AromaticContact CE2-ND1 3.75Å; Y103-H342 AromaticContact CZ-ND1 3.7Å; Y103-H342 PolarHBondContact OH-CE1 3.33Å; Y103-H342 PolarHBondContact OH-ND1 3.13Å
104	A	88.4	Confident	87.6	Confident	5 Å²	5	28.7 Å²	28.7	4%	0.041	16%	0.159	C	C	.	.	H	α-helix	trans	-65.1	-37.9	179.2	0	0	0	0	0	111.9	K98 A101 L107 E108	K98-A104 HydrophobicContact CB-CB 4.24Å; A101-A104 PolarHBondContact O-N 3.48Å; A104-L107 PolarHBondContact O-N 3.35Å; A104-E108 WeakPolarHBondContact O-CB 3.3Å; A104-E108 PolarHBondContact O-N 2.96Å
105	Y	91.6	Very high	87.7	Confident	1 Å²	1	28.3 Å²	28.3	0%	0.004	16%	0.157	C	C	.	.	H	α-helix	trans	-66.9	-44.6	178.5	-54.7	-24.9	0	0	0	112.1	Y89 L92 G93 I96 A101 Y103 L107 E108 A109 N245	Y89-Y105 HydrophobicContact CD1-CD2 4.42Å; Y89-Y105 AromaticContact CD1-CE2 3.76Å; Y89-Y105 HydrophobicContact CD1-CE2 3.76Å; Y89-Y105 HydrophobicContact CE1-CD2 4.17Å; Y89-Y105 AromaticContact CE1-CE2 3.89Å; Y89-Y105 HydrophobicContact CE1-CE2 3.89Å; Y89-Y105 HydrophobicContact CG-CE2 4.48Å; L92-Y105 HydrophobicContact CB-CD1 4.28Å; L92-Y105 HydrophobicContact CB-CD2 3.92Å; L92-Y105 HydrophobicContact CB-CE1 4.15Å; L92-Y105 HydrophobicContact CB-CE2 3.75Å; L92-Y105 HydrophobicContact CB-CG 4.18Å; L92-Y105 HydrophobicContact CD1-CD2 3.81Å; L92-Y105 HydrophobicContact CD1-CE2 4.29Å; L92-Y105 HydrophobicContact CD1-CG 4.26Å; L92-Y105 HydrophobicContact CG-CD2 4.41Å; G93-Y105 WeakPolarHBondContact CA-OH 3.28Å; G93-Y105 PolarHBondContact N-OH 3.21Å; I96-Y105 HydrophobicContact CB-CD1 3.9Å; I96-Y105 HydrophobicContact CB-CE1 3.99Å; I96-Y105 HydrophobicContact CD1-CD1 3.91Å; I96-Y105 HydrophobicContact CG1-CD1 4.48Å; I96-Y105 HydrophobicContact CG2-CD1 4.07Å; I96-Y105 HydrophobicContact CG2-CE1 4.33Å; A101-Y105 HydrophobicContact CB-CE2 4.46Å; A101-Y105 WeakPolarHBondContact O-CD1 3.42Å; A101-Y105 VanDerWaalsContact O-CD2 3.32Å; A101-Y105 WeakPolarHBondContact O-CD2 3.35Å; A101-Y105 PolarHBondContact O-N 2.98Å; Y103-Y105 VanDerWaalsContact C-N 3.34Å; Y103-Y105 PolarHBondContact O-N 3.3Å; Y105-L107 VanDerWaalsContact C-N 3.33Å; Y105-E108 PolarHBondContact O-N 2.87Å; Y105-A109 VanDerWaalsContact O-CB 3.29Å; Y105-A109 WeakPolarHBondContact O-CB 3.32Å; Y105-A109 PolarHBondContact O-N 2.89Å; Y105-N245 WeakPolarHBondContact OH-CB 3.47Å; Y105-N245 PolarHBondContact OH-ND2 2.99Å
106	I	93.6	Very high	87.9	Confident	0 Å²	0	27.5 Å²	27.5	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-67.2	-37.8	177	-69	167.7	0	0	0	110.4	S102 Y103 A109 F110 G111 L114 A115 R118 F391 L394	S102-I106 WeakPolarHBondContact O-CB 3.32Å; S102-I106 WeakPolarHBondContact O-CD1 3.13Å; S102-I106 VanDerWaalsContact O-CG1 3.23Å; S102-I106 WeakPolarHBondContact O-CG1 3.24Å; S102-I106 PolarHBondContact O-N 3.45Å; Y103-I106 PolarHBondContact O-N 3.17Å; I106-A109 PolarHBondContact O-N 3.35Å; I106-F110 HydrophobicContact CG2-CD2 4.21Å; I106-F110 PolarHBondContact O-N 3.22Å; I106-G111 PolarHBondContact O-N 2.88Å; I106-L114 HydrophobicContact CG2-CB 3.72Å; I106-A115 HydrophobicContact CG2-CB 4.42Å; I106-R118 HydrophobicContact CD1-CB 3.99Å; I106-R118 HydrophobicContact CD1-CG 3.86Å; I106-F391 HydrophobicContact CD1-CD1 4.1Å; I106-L394 HydrophobicContact CD1-CB 4.44Å; I106-L394 HydrophobicContact CD1-CD2 4.1Å; I106-L394 HydrophobicContact CD1-CG 4.34Å; I106-L394 HydrophobicContact CG1-CD2 4.5Å; I106-L394 HydrophobicContact CG1-CG 4.45Å; I106-L394 HydrophobicContact CG2-CD2 4.47Å
107	L	92.1	Very high	88.2	Confident	36 Å²	36	28 Å²	28	19%	0.188	15%	0.154	C	C	.	.	H	α-helix	trans	-60.1	-47.1	175.9	-178.2	60.7	0	0	0	111.9	Y103 A104 Y105 G111 A115 E340	Y103-L107 HydrophobicContact CE1-CD2 4.26Å; Y103-L107 VanDerWaalsContact O-CB 3.28Å; Y103-L107 WeakPolarHBondContact O-CB 3.46Å; Y103-L107 PolarHBondContact O-N 3.38Å; A104-L107 PolarHBondContact O-N 3.35Å; Y105-L107 VanDerWaalsContact C-N 3.33Å; L107-G111 WeakPolarHBondContact O-CA 3.21Å; L107-G111 PolarHBondContact O-N 3.17Å; L107-A115 HydrophobicContact CB-CB 3.69Å; L107-A115 HydrophobicContact CD1-CB 3.75Å; L107-A115 HydrophobicContact CG-CB 4.31Å; L107-E340 HydrophobicContact CD2-CG 4.26Å
108	E	91.6	Very high	88.8	Confident	61 Å²	61	24.7 Å²	24.7	29%	0.285	13%	0.133	S	C	.	.	H	α-helix	trans	-69.8	-37.7	179.9	-169.5	80.8	-177.6	0	0	112.2	I96 K98 A104 Y105 R409	I96-E108 HydrophobicContact CD1-CB 3.94Å; I96-E108 HydrophobicContact CD1-CG 3.95Å; I96-E108 HydrophobicContact CG1-CG 4.37Å; K98-E108 IonicContact NZ-OE2 3.58Å; K98-E108 PolarHBondContact NZ-OE2 2.87Å; A104-E108 WeakPolarHBondContact O-CB 3.3Å; A104-E108 PolarHBondContact O-N 2.96Å; Y105-E108 PolarHBondContact O-N 2.87Å; E108-R409 IonicContact OE1-CZ 3.47Å; E108-R409 IonicContact OE1-NH1 2.68Å; E108-R409 PolarHBondContact OE1-NH1 2.88Å; E108-R409 IonicContact OE1-NH2 3.13Å; E108-R409 PolarHBondContact OE1-NH2 3.47Å; E108-R409 VanDerWaalsContact OE1-NH2 3.13Å
109	A	93.1	Very high	89.5	Confident	6 Å²	6	19.8 Å²	19.8	5%	0.05	11%	0.112	C	C	.	.	H	α-helix	trans	-80.3	-45.9	-177.3	0	0	0	0	0	113.2	Y105 I106 Y401 L402	Y105-A109 VanDerWaalsContact O-CB 3.29Å; Y105-A109 WeakPolarHBondContact O-CB 3.32Å; Y105-A109 PolarHBondContact O-N 2.89Å; I106-A109 PolarHBondContact O-N 3.35Å; A109-Y401 HydrophobicContact CB-CD1 4.5Å; A109-Y401 WeakPolarHBondContact O-CD1 3.39Å; A109-Y401 WeakPolarHBondContact O-CE1 3.45Å; A109-L402 HydrophobicContact CB-CD1 4.11Å; A109-L402 HydrophobicContact CB-CD2 4.5Å; A109-L402 HydrophobicContact CB-CG 4.07Å
110	F	93.9	Very high	90.6	Very high	71 Å²	71	21 Å²	21	31%	0.311	11%	0.112	S	C	.	.	H	α-helix	trans	-120.1	-7	-168.3	-58.5	-67.9	0	0	0	114.7	I106 L114 L394 L397 Y401	I106-F110 HydrophobicContact CG2-CD2 4.21Å; I106-F110 PolarHBondContact O-N 3.22Å; F110-L114 HydrophobicContact CB-CB 4.15Å; F110-L114 HydrophobicContact CB-CD1 3.68Å; F110-L114 HydrophobicContact CB-CG 4.45Å; F110-L114 HydrophobicContact CD1-CD1 4.41Å; F110-L114 HydrophobicContact CD2-CD1 4.38Å; F110-L114 HydrophobicContact CG-CD1 3.93Å; F110-L394 HydrophobicContact CD2-CD1 4.38Å; F110-L394 HydrophobicContact CD2-CG 4.39Å; F110-L394 HydrophobicContact CE2-CD1 3.84Å; F110-L394 HydrophobicContact CE2-CG 4.03Å; F110-L394 WeakPolarHBondContact CE2-O 3.41Å; F110-L394 HydrophobicContact CZ-CD1 4.16Å; F110-L397 HydrophobicContact CZ-CB 4.45Å; F110-Y401 HydrophobicContact CE1-CD1 4.48Å; F110-Y401 HydrophobicContact CE1-CG 4.32Å
111	G	91.3	Very high	91.5	Very high	29 Å²	29	20.8 Å²	20.8	30%	0.299	11%	0.11	S	C	.	.			trans	88.5	-177.3	177.6	0	0	0	0	0	115	I106 L107 F113 A115	I106-G111 PolarHBondContact O-N 2.88Å; L107-G111 WeakPolarHBondContact O-CA 3.21Å; L107-G111 PolarHBondContact O-N 3.17Å; G111-F113 PolarHBondContact O-N 2.93Å; G111-A115 WeakPolarHBondContact O-CB 3.47Å; G111-A115 PolarHBondContact O-N 3.44Å
112	G	89.6	Confident	91.9	Very high	20 Å²	20	20.8 Å²	20.8	21%	0.206	11%	0.11	C	C	.	.	H	α-helix	trans	-62.6	-32.6	-167.3	0	0	0	0	0	115.5	A115 F116 H342	G112-A115 PolarHBondContact O-N 2.98Å; G112-F116 WeakPolarHBondContact O-CB 3.48Å; G112-F116 PolarHBondContact O-N 2.98Å; G112-H342 PolarHBondContact O-CE1 3.26Å
113	F	92.4	Very high	92.1	Very high	74 Å²	74	21 Å²	21	33%	0.325	11%	0.111	S	C	.	.	H	α-helix	trans	-64	-55.7	-177.8	175.1	-111	0	0	0	112.5	G111 A115 F116 I117 V453 Y456 F457	G111-F113 PolarHBondContact O-N 2.93Å; F113-A115 VanDerWaalsContact C-N 3.29Å; F113-A115 PolarHBondContact O-N 3.46Å; F113-F116 PolarHBondContact O-N 2.69Å; F113-I117 HydrophobicContact CE2-CD1 4.32Å; F113-I117 HydrophobicContact CE2-CG1 4.2Å; F113-I117 HydrophobicContact CZ-CD1 4.5Å; F113-I117 HydrophobicContact CZ-CG1 4.2Å; F113-I117 WeakPolarHBondContact O-CG1 3.26Å; F113-I117 PolarHBondContact O-N 3.32Å; F113-V453 HydrophobicContact CE2-CG1 4.24Å; F113-V453 HydrophobicContact CE2-CG2 4.21Å; F113-V453 HydrophobicContact CZ-CG1 4.33Å; F113-V453 HydrophobicContact CZ-CG2 3.93Å; F113-Y456 HydrophobicContact CB-CE1 3.99Å; F113-Y456 AromaticContact CD2-CD1 3.49Å; F113-Y456 HydrophobicContact CD2-CD1 3.49Å; F113-Y456 VanDerWaalsContact CD2-CD1 3.49Å; F113-Y456 AromaticContact CD2-CE1 3.71Å; F113-Y456 HydrophobicContact CD2-CE1 3.71Å; F113-Y456 AromaticContact CD2-CG 3.9Å; F113-Y456 HydrophobicContact CD2-CG 3.9Å; F113-Y456 HydrophobicContact CE2-CD1 4.16Å; F113-Y456 HydrophobicContact CE2-CG 4.48Å; F113-Y456 HydrophobicContact CG-CE1 4.33Å; F113-Y456 PolarHBondContact N-OH 3.17Å; F113-F457 HydrophobicContact CE2-CE2 4.31Å
114	L	93.4	Very high	92.2	Very high	55 Å²	55	22.1 Å²	22.1	29%	0.288	12%	0.118	S	C	.	.	H	α-helix	trans	-68.6	-31.5	180	-77.3	177.9	0	0	0	111.9	I106 F110 I117 R118 L394	I106-L114 HydrophobicContact CG2-CB 3.72Å; F110-L114 HydrophobicContact CB-CB 4.15Å; F110-L114 HydrophobicContact CB-CD1 3.68Å; F110-L114 HydrophobicContact CB-CG 4.45Å; F110-L114 HydrophobicContact CD1-CD1 4.41Å; F110-L114 HydrophobicContact CD2-CD1 4.38Å; F110-L114 HydrophobicContact CG-CD1 3.93Å; L114-I117 PolarHBondContact O-N 3.42Å; L114-R118 WeakPolarHBondContact O-CB 3.49Å; L114-R118 PolarHBondContact O-N 3.36Å; L114-L394 HydrophobicContact CD1-CD2 4.44Å; L114-L394 HydrophobicContact CD2-CD2 4.47Å
115	A	92.6	Very high	92.4	Very high	0 Å²	0	22 Å²	22	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-63.1	-42.4	172.3	0	0	0	0	0	111.9	Y103 I106 L107 G111 G112 F113 R118 L119	Y103-A115 HydrophobicContact CD2-CB 4.04Å; Y103-A115 VanDerWaalsContact CD2-O 3.29Å; Y103-A115 WeakPolarHBondContact CD2-O 3.47Å; Y103-A115 HydrophobicContact CE2-CB 3.73Å; Y103-A115 WeakPolarHBondContact CE2-O 3.48Å; I106-A115 HydrophobicContact CG2-CB 4.42Å; L107-A115 HydrophobicContact CB-CB 3.69Å; L107-A115 HydrophobicContact CD1-CB 3.75Å; L107-A115 HydrophobicContact CG-CB 4.31Å; G111-A115 WeakPolarHBondContact O-CB 3.47Å; G111-A115 PolarHBondContact O-N 3.44Å; G112-A115 PolarHBondContact O-N 2.98Å; F113-A115 VanDerWaalsContact C-N 3.29Å; F113-A115 PolarHBondContact O-N 3.46Å; A115-R118 WeakPolarHBondContact O-CB 3.44Å; A115-R118 PolarHBondContact O-N 3.25Å; A115-L119 WeakPolarHBondContact O-CB 3.29Å; A115-L119 PolarHBondContact O-N 3.12Å
116	F	93	Very high	92.4	Very high	4 Å²	4	22.1 Å²	22.1	2%	0.018	12%	0.117	C	C	.	.	H	α-helix	trans	-62.4	-45.8	174	175	-86.3	0	0	0	111.5	G112 F113 R118 L119 W120 H342 G452 V455 Y456	G112-F116 WeakPolarHBondContact O-CB 3.48Å; G112-F116 PolarHBondContact O-N 2.98Å; F113-F116 PolarHBondContact O-N 2.69Å; F116-R118 VanDerWaalsContact C-N 3.3Å; F116-R118 PolarHBondContact O-N 3.37Å; F116-L119 WeakPolarHBondContact O-CB 3.48Å; F116-L119 PolarHBondContact O-N 3.05Å; F116-L119 VanDerWaalsContact O-N 3.09Å; F116-W120 HydrophobicContact CD1-CB 4.38Å; F116-W120 HydrophobicContact CE1-CB 3.99Å; F116-W120 HydrophobicContact CE1-CD2 4.28Å; F116-W120 HydrophobicContact CE1-CE3 4.27Å; F116-W120 HydrophobicContact CE1-CG 4.19Å; F116-W120 HydrophobicContact CZ-CB 4.38Å; F116-W120 HydrophobicContact CZ-CD2 4.19Å; F116-W120 AromaticContact CZ-CE3 3.72Å; F116-W120 HydrophobicContact CZ-CE3 3.72Å; F116-W120 HydrophobicContact CZ-CG 4.5Å; F116-W120 HydrophobicContact CZ-CZ3 4.38Å; F116-W120 VanDerWaalsContact O-CB 3.26Å; F116-W120 WeakPolarHBondContact O-CB 3.29Å; F116-W120 PolarHBondContact O-N 3.44Å; F116-H342 HydrophobicContact CD2-CB 3.99Å; F116-H342 WeakPolarHBondContact CD2-O 3.44Å; F116-H342 WeakPolarHBondContact CE2-O 3.44Å; F116-G452 WeakPolarHBondContact CE1-O 3.07Å; F116-V455 HydrophobicContact CZ-CB 4.18Å; F116-V455 HydrophobicContact CZ-CG1 3.85Å; F116-Y456 HydrophobicContact CB-CD2 3.43Å; F116-Y456 VanDerWaalsContact CB-CD2 3.43Å; F116-Y456 HydrophobicContact CB-CE2 3.8Å; F116-Y456 HydrophobicContact CB-CG 4.45Å; F116-Y456 AromaticContact CD1-CD2 3.81Å; F116-Y456 HydrophobicContact CD1-CD2 3.81Å; F116-Y456 HydrophobicContact CD1-CG 4.16Å; F116-Y456 AromaticContact CD2-CD2 3.95Å; F116-Y456 HydrophobicContact CD2-CD2 3.95Å; F116-Y456 AromaticContact CG-CD2 3.44Å; F116-Y456 HydrophobicContact CG-CD2 3.44Å; F116-Y456 VanDerWaalsContact CG-CD2 3.44Å; F116-Y456 HydrophobicContact CG-CE2 4.28Å; F116-Y456 HydrophobicContact CG-CG 4.25Å
117	I	94.1	Very high	92.2	Very high	14 Å²	14	23.4 Å²	23.4	7%	0.072	12%	0.123	C	C	.	.	H	α-helix	trans	-62.6	-38.9	179.5	-61.8	-64.6	0	0	0	111.1	F113 L114 T121 F391 A449 V453	F113-I117 HydrophobicContact CE2-CD1 4.32Å; F113-I117 HydrophobicContact CE2-CG1 4.2Å; F113-I117 HydrophobicContact CZ-CD1 4.5Å; F113-I117 HydrophobicContact CZ-CG1 4.2Å; F113-I117 WeakPolarHBondContact O-CG1 3.26Å; F113-I117 PolarHBondContact O-N 3.32Å; L114-I117 PolarHBondContact O-N 3.42Å; I117-T121 WeakPolarHBondContact O-CB 3.3Å; I117-T121 PolarHBondContact O-N 3.45Å; I117-T121 PolarHBondContact O-OG1 3.32Å; I117-F391 HydrophobicContact CG2-CE1 4.39Å; I117-F391 HydrophobicContact CG2-CZ 3.99Å; I117-A449 HydrophobicContact CG2-CB 4.43Å; I117-V453 HydrophobicContact CD1-CG2 3.87Å
118	R	93	Very high	92.3	Very high	5 Å²	5	21.7 Å²	21.7	2%	0.019	11%	0.114	C	C	.	.	H	α-helix	trans	-58.9	-46.8	170.6	170	66.6	-175	74.2	-2.9	112.1	I106 L114 A115 F116 S122 F391	I106-R118 HydrophobicContact CD1-CB 3.99Å; I106-R118 HydrophobicContact CD1-CG 3.86Å; L114-R118 WeakPolarHBondContact O-CB 3.49Å; L114-R118 PolarHBondContact O-N 3.36Å; A115-R118 WeakPolarHBondContact O-CB 3.44Å; A115-R118 PolarHBondContact O-N 3.25Å; F116-R118 VanDerWaalsContact C-N 3.3Å; F116-R118 PolarHBondContact O-N 3.37Å; R118-S122 PolarHBondContact NH1-OG 3.28Å; R118-S122 PolarHBondContact O-N 3.02Å; R118-F391 HydrophobicContact CB-CD1 3.78Å; R118-F391 HydrophobicContact CB-CE1 3.8Å; R118-F391 HydrophobicContact CB-CG 4.43Å; R118-F391 HydrophobicContact CB-CZ 4.49Å; R118-F391 HydrophobicContact CG-CD1 4.17Å; R118-F391 HydrophobicContact CG-CG 4.42Å
119	L	92.1	Very high	92.4	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-65.7	-48.1	-179.3	-179.6	64.1	0	0	0	111.2	Y103 A115 F116 T121 S122 L123 L333 H342 L343	Y103-L119 HydrophobicContact CD2-CB 3.88Å; Y103-L119 HydrophobicContact CE2-CB 3.99Å; Y103-L119 HydrophobicContact CE2-CD2 4.02Å; Y103-L119 HydrophobicContact CE2-CG 4.5Å; A115-L119 WeakPolarHBondContact O-CB 3.29Å; A115-L119 PolarHBondContact O-N 3.12Å; F116-L119 WeakPolarHBondContact O-CB 3.48Å; F116-L119 PolarHBondContact O-N 3.05Å; F116-L119 VanDerWaalsContact O-N 3.09Å; L119-T121 VanDerWaalsContact C-N 3.3Å; L119-T121 PolarHBondContact O-N 3.34Å; L119-S122 WeakPolarHBondContact O-CB 3.34Å; L119-S122 PolarHBondContact O-N 3.48Å; L119-S122 VanDerWaalsContact O-N 3.11Å; L119-L123 HydrophobicContact CD1-CD1 4.37Å; L119-L123 HydrophobicContact CG-CD1 3.96Å; L119-L123 WeakPolarHBondContact O-CD1 3.35Å; L119-L123 WeakPolarHBondContact O-CG 3.43Å; L119-L123 PolarHBondContact O-N 3.2Å; L119-L333 HydrophobicContact CD1-CD1 3.97Å; L119-L333 HydrophobicContact CD1-CD2 4.33Å; L119-L333 HydrophobicContact CD1-CG 3.8Å; L119-H342 HydrophobicContact CD2-CB 3.94Å; L119-L343 HydrophobicContact CD1-CD1 4.32Å; L119-L343 HydrophobicContact CD2-CD1 3.8Å; L119-L343 HydrophobicContact CD2-CD2 4.26Å; L119-L343 HydrophobicContact CD2-CG 3.73Å; L119-L343 HydrophobicContact CG-CD1 4.19Å; L119-L343 HydrophobicContact CG-CG 4.42Å
120	W	93.1	Very high	92.4	Very high	53 Å²	53	19.3 Å²	19.3	20%	0.201	10%	0.103	C	C	.	.	H	α-helix	trans	-55.1	-44.7	175.8	-173.3	-104.2	0	0	0	112	F116 L123 L124 I448 S451 G452 V455	F116-W120 HydrophobicContact CD1-CB 4.38Å; F116-W120 HydrophobicContact CE1-CB 3.99Å; F116-W120 HydrophobicContact CE1-CD2 4.28Å; F116-W120 HydrophobicContact CE1-CE3 4.27Å; F116-W120 HydrophobicContact CE1-CG 4.19Å; F116-W120 HydrophobicContact CZ-CB 4.38Å; F116-W120 HydrophobicContact CZ-CD2 4.19Å; F116-W120 AromaticContact CZ-CE3 3.72Å; F116-W120 HydrophobicContact CZ-CE3 3.72Å; F116-W120 HydrophobicContact CZ-CG 4.5Å; F116-W120 HydrophobicContact CZ-CZ3 4.38Å; F116-W120 VanDerWaalsContact O-CB 3.26Å; F116-W120 WeakPolarHBondContact O-CB 3.29Å; F116-W120 PolarHBondContact O-N 3.44Å; W120-L123 WeakPolarHBondContact O-CB 3.49Å; W120-L123 PolarHBondContact O-N 3.47Å; W120-L124 HydrophobicContact CD2-CD1 4.09Å; W120-L124 HydrophobicContact CG-CD1 4.48Å; W120-L124 HydrophobicContact CH2-CD1 4.37Å; W120-L124 HydrophobicContact CZ2-CD1 3.57Å; W120-L124 WeakPolarHBondContact O-CG 3.47Å; W120-L124 PolarHBondContact O-N 3.09Å; W120-I448 PolarHBondContact NE1-O 3.35Å; W120-S451 PolarHBondContact NE1-OG 3.49Å; W120-S451 VanDerWaalsContact NE1-OG 3.11Å; W120-G452 VanDerWaalsContact CD1-CA 3.45Å; W120-V455 HydrophobicContact CH2-CB 4.42Å; W120-V455 HydrophobicContact CH2-CG1 4.09Å; W120-V455 HydrophobicContact CH2-CG2 4Å; W120-V455 HydrophobicContact CZ2-CG2 4.02Å; W120-V455 HydrophobicContact CZ3-CG1 3.98Å
121	T	93.1	Very high	92.4	Very high	0 Å²	0	15.9 Å²	15.9	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-71.5	-33.1	178.7	-50	0	0	0	0	112	I117 L119 I125 I126 F391	I117-T121 WeakPolarHBondContact O-CB 3.3Å; I117-T121 PolarHBondContact O-N 3.45Å; I117-T121 PolarHBondContact O-OG1 3.32Å; L119-T121 VanDerWaalsContact C-N 3.3Å; L119-T121 PolarHBondContact O-N 3.34Å; T121-I125 HydrophobicContact CG2-CB 4.24Å; T121-I125 HydrophobicContact CG2-CD1 3.77Å; T121-I125 HydrophobicContact CG2-CG1 4.2Å; T121-I125 WeakPolarHBondContact O-CA 3.41Å; T121-I125 WeakPolarHBondContact O-CB 3.24Å; T121-I125 PolarHBondContact O-N 2.87Å; T121-I126 PolarHBondContact O-N 3.28Å; T121-I126 VanDerWaalsContact O-N 3.15Å; T121-F391 VanDerWaalsContact CB-CE2 3.45Å; T121-F391 HydrophobicContact CG2-CD2 4.37Å; T121-F391 HydrophobicContact CG2-CE2 3.63Å; T121-F391 WeakPolarHBondContact OG1-CE2 3.4Å
122	S	91.5	Very high	92.6	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.074	C	C	.	.	I	π-helix	trans	-62.8	-48.3	172.3	-119.5	0	0	0	0	112	R118 L119 L124 I126 E127	R118-S122 PolarHBondContact NH1-OG 3.28Å; R118-S122 PolarHBondContact O-N 3.02Å; L119-S122 WeakPolarHBondContact O-CB 3.34Å; L119-S122 PolarHBondContact O-N 3.48Å; L119-S122 VanDerWaalsContact O-N 3.11Å; S122-L124 PolarHBondContact O-N 3.39Å; S122-I126 PolarHBondContact O-N 3.28Å; S122-E127 WeakPolarHBondContact O-CG 3.27Å; S122-E127 PolarHBondContact O-N 2.92Å; S122-E127 PolarHBondContact OG-OE1 3.11Å
123	L	90.3	Very high	92.9	Very high	4 Å²	4	13.6 Å²	13.6	2%	0.021	6%	0.064	C	C	.	.	I	π-helix	trans	-58.7	-44.8	-180	-82	155	0	0	0	112.6	L119 W120 P128 F334 L343 F363	L119-L123 HydrophobicContact CD1-CD1 4.37Å; L119-L123 HydrophobicContact CG-CD1 3.96Å; L119-L123 WeakPolarHBondContact O-CD1 3.35Å; L119-L123 WeakPolarHBondContact O-CG 3.43Å; L119-L123 PolarHBondContact O-N 3.2Å; W120-L123 WeakPolarHBondContact O-CB 3.49Å; W120-L123 PolarHBondContact O-N 3.47Å; L123-P128 WeakPolarHBondContact O-CD 3.26Å; L123-P128 WeakPolarHBondContact O-CG 3.49Å; L123-F334 HydrophobicContact CB-CE1 4.48Å; L123-F334 HydrophobicContact CD2-CD1 3.29Å; L123-F334 HydrophobicContact CD2-CD2 3.83Å; L123-F334 HydrophobicContact CD2-CE1 3.13Å; L123-F334 HydrophobicContact CD2-CE2 3.64Å; L123-F334 HydrophobicContact CD2-CG 3.7Å; L123-F334 HydrophobicContact CD2-CZ 3.34Å; L123-F334 HydrophobicContact CG-CD1 3.93Å; L123-F334 HydrophobicContact CG-CE1 3.67Å; L123-F334 HydrophobicContact CG-CZ 4.22Å; L123-L343 HydrophobicContact CD1-CD1 3.89Å; L123-L343 HydrophobicContact CD1-CD2 3.42Å; L123-L343 VanDerWaalsContact CD1-CD2 3.42Å; L123-L343 HydrophobicContact CD1-CG 4.24Å; L123-F363 HydrophobicContact CD2-CD1 4.23Å; L123-F363 HydrophobicContact CD2-CE1 3.81Å
124	L	92.2	Very high	92.9	Very high	27 Å²	27	10.7 Å²	10.7	14%	0.141	5%	0.052	C	C	.	.	I	π-helix	trans	-92.8	-31.1	-171.6	-65	-173	0	0	0	113.6	W120 S122 F363 M367 Y371 I448	W120-L124 HydrophobicContact CD2-CD1 4.09Å; W120-L124 HydrophobicContact CG-CD1 4.48Å; W120-L124 HydrophobicContact CH2-CD1 4.37Å; W120-L124 HydrophobicContact CZ2-CD1 3.57Å; W120-L124 WeakPolarHBondContact O-CG 3.47Å; W120-L124 PolarHBondContact O-N 3.09Å; S122-L124 PolarHBondContact O-N 3.39Å; L124-F363 HydrophobicContact CD2-CZ 4.18Å; L124-M367 HydrophobicContact CD2-CE 3.8Å; L124-M367 HydrophobicContact CD2-SD 4.31Å; L124-Y371 WeakPolarHBondContact O-CE2 3.29Å; L124-Y371 PolarHBondContact O-OH 3.34Å; L124-I448 HydrophobicContact CB-CG2 3.91Å; L124-I448 HydrophobicContact CD1-CG2 3.88Å
125	I	91.9	Very high	93	Very high	2 Å²	2	8 Å²	8	1%	0.01	4%	0.039	C	C	.	.	I	π-helix	trans	-118.2	-63.1	-172.5	-50.7	-179.8	0	0	0	110.7	T121 P128 T129 I448	T121-I125 HydrophobicContact CG2-CB 4.24Å; T121-I125 HydrophobicContact CG2-CD1 3.77Å; T121-I125 HydrophobicContact CG2-CG1 4.2Å; T121-I125 WeakPolarHBondContact O-CA 3.41Å; T121-I125 WeakPolarHBondContact O-CB 3.24Å; T121-I125 PolarHBondContact O-N 2.87Å; I125-P128 WeakPolarHBondContact O-CD 3.49Å; I125-T129 WeakPolarHBondContact O-CB 3.46Å; I125-T129 PolarHBondContact O-N 3.43Å; I125-T129 PolarHBondContact O-OG1 2.93Å; I125-I448 HydrophobicContact CD1-CB 3.71Å; I125-I448 HydrophobicContact CD1-CD1 4.09Å; I125-I448 HydrophobicContact CD1-CG2 3.65Å; I125-I448 HydrophobicContact CG1-CB 4.26Å; I125-I448 HydrophobicContact CG1-CD1 4.2Å; I125-I448 HydrophobicContact CG1-CG2 3.71Å
126	I	91.6	Very high	93.1	Very high	3 Å²	3	8.2 Å²	8.2	2%	0.015	4%	0.039	C	C	.	.	I	π-helix	trans	-63.1	-55.1	-163	-56.1	175.7	0	0	0	111.4	T121 S122 S130 Y384 Y388 F391	T121-I126 PolarHBondContact O-N 3.28Å; T121-I126 VanDerWaalsContact O-N 3.15Å; S122-I126 PolarHBondContact O-N 3.28Å; I126-S130 WeakPolarHBondContact O-CB 3.32Å; I126-S130 PolarHBondContact O-N 3.48Å; I126-S130 VanDerWaalsContact O-N 3.14Å; I126-Y384 HydrophobicContact CB-CD2 4.44Å; I126-Y384 HydrophobicContact CG2-CD2 3.75Å; I126-Y384 HydrophobicContact CG2-CE2 3.44Å; I126-Y384 VanDerWaalsContact CG2-CE2 3.44Å; I126-Y384 WeakPolarHBondContact O-CD2 3.28Å; I126-Y388 HydrophobicContact CG2-CD2 4.06Å; I126-F391 HydrophobicContact CD1-CD2 4.46Å
127	E	91.4	Very high	93.1	Very high	27 Å²	27	8 Å²	8	13%	0.126	4%	0.039	C	C	.	.	H	α-helix	trans	-67.6	-50.9	-176.1	-51.6	-60.6	155.8	0	0	112.2	S122 T129 S130 Q131 A330	S122-E127 WeakPolarHBondContact O-CG 3.27Å; S122-E127 PolarHBondContact O-N 2.92Å; S122-E127 PolarHBondContact OG-OE1 3.11Å; E127-T129 PolarHBondContact O-N 3.41Å; E127-S130 PolarHBondContact O-N 3.43Å; E127-Q131 VanDerWaalsContact O-CG 3.26Å; E127-Q131 WeakPolarHBondContact O-CG 3.37Å; E127-Q131 PolarHBondContact O-N 2.93Å; E127-Q131 VanDerWaalsContact O-N 3.08Å; E127-Q131 PolarHBondContact O-NE2 2.92Å; E127-A330 HydrophobicContact CB-CB 3.94Å; E127-A330 HydrophobicContact CG-CB 3.86Å
128	P	93.8	Very high	93.1	Very high	0 Å²	0	8.7 Å²	8.7	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-64.8	-38	-177.4	-24.1	37.3	0	0	0	113.3	L123 I125 Q131 A132 M367 A368 Y371	L123-P128 WeakPolarHBondContact O-CD 3.26Å; L123-P128 WeakPolarHBondContact O-CG 3.49Å; I125-P128 WeakPolarHBondContact O-CD 3.49Å; P128-Q131 PolarHBondContact O-N 3.19Å; P128-A132 WeakPolarHBondContact O-CB 3.27Å; P128-A132 PolarHBondContact O-N 2.95Å; P128-M367 HydrophobicContact CB-CB 3.77Å; P128-M367 HydrophobicContact CG-CB 3.55Å; P128-M367 HydrophobicContact CG-CG 4.44Å; P128-A368 HydrophobicContact CB-CB 4.48Å; P128-Y371 HydrophobicContact CB-CD2 3.61Å; P128-Y371 HydrophobicContact CB-CE2 3.91Å
129	T	93.7	Very high	93.2	Very high	0 Å²	0	8.4 Å²	8.4	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-67.7	-44.2	-179.8	-58	0	0	0	0	110.9	I125 E127 Q131 A132 V133 Y371 L380	I125-T129 WeakPolarHBondContact O-CB 3.46Å; I125-T129 PolarHBondContact O-N 3.43Å; I125-T129 PolarHBondContact O-OG1 2.93Å; E127-T129 PolarHBondContact O-N 3.41Å; T129-Q131 PolarHBondContact O-N 2.99Å; T129-A132 PolarHBondContact O-N 2.95Å; T129-V133 WeakPolarHBondContact O-CG2 3.4Å; T129-V133 PolarHBondContact O-N 3.1Å; T129-Y371 WeakPolarHBondContact OG1-CE1 3.4Å; T129-L380 HydrophobicContact CG2-CB 3.67Å; T129-L380 HydrophobicContact CG2-CD2 3.94Å; T129-L380 HydrophobicContact CG2-CG 4.4Å; T129-L380 WeakPolarHBondContact CG2-O 3.27Å
130	S	92.6	Very high	93.1	Very high	17 Å²	17	9.6 Å²	9.6	12%	0.119	5%	0.046	C	C	.	.	H	α-helix	trans	-59.7	-46.5	175.8	-176.5	0	0	0	0	111.2	I126 E127 A132 V133 I134	I126-S130 WeakPolarHBondContact O-CB 3.32Å; I126-S130 PolarHBondContact O-N 3.48Å; I126-S130 VanDerWaalsContact O-N 3.14Å; E127-S130 PolarHBondContact O-N 3.43Å; S130-A132 PolarHBondContact O-N 3.38Å; S130-V133 PolarHBondContact O-N 3.38Å; S130-I134 WeakPolarHBondContact O-CD1 3.31Å; S130-I134 VanDerWaalsContact O-CG1 3.24Å; S130-I134 WeakPolarHBondContact O-CG1 3.14Å; S130-I134 PolarHBondContact O-N 3.46Å
131	Q	94.5	Very high	93	Very high	0 Å²	0	7 Å²	7	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-62.1	-41.6	177.8	-69.3	166.1	31.4	0	0	112.5	E127 P128 T129 I134 A135 L323 S326 I327 N364 A368	E127-Q131 VanDerWaalsContact O-CG 3.26Å; E127-Q131 WeakPolarHBondContact O-CG 3.37Å; E127-Q131 PolarHBondContact O-N 2.93Å; E127-Q131 VanDerWaalsContact O-N 3.08Å; E127-Q131 PolarHBondContact O-NE2 2.92Å; P128-Q131 PolarHBondContact O-N 3.19Å; T129-Q131 PolarHBondContact O-N 2.99Å; Q131-I134 PolarHBondContact O-N 2.93Å; Q131-A135 VanDerWaalsContact O-CB 3.32Å; Q131-A135 WeakPolarHBondContact O-CB 3.15Å; Q131-A135 PolarHBondContact O-N 3.16Å; Q131-L323 HydrophobicContact CB-CD1 3.62Å; Q131-L323 HydrophobicContact CG-CD1 3.84Å; Q131-S326 WeakPolarHBondContact CG-OG 3.44Å; Q131-S326 PolarHBondContact NE2-OG 3.26Å; Q131-I327 HydrophobicContact CG-CG1 4.49Å; Q131-N364 VanDerWaalsContact CD-ND2 3.26Å; Q131-N364 PolarHBondContact NE2-ND2 3.31Å; Q131-N364 PolarHBondContact NE2-OD1 3.36Å; Q131-N364 VanDerWaalsContact NE2-OD1 3.14Å; Q131-N364 PolarHBondContact OE1-ND2 2.64Å; Q131-N364 PolarHBondContact OE1-OD1 2.96Å; Q131-A368 HydrophobicContact CB-CB 4.09Å
132	A	95.8	Very high	92.9	Very high	0 Å²	0	9.8 Å²	9.8	0%	0	5%	0.05	C	C	.	.	H	α-helix	trans	-61.5	-46.1	175.2	0	0	0	0	0	111.6	P128 T129 S130 I134 A135 I136 L372 L380	P128-A132 WeakPolarHBondContact O-CB 3.27Å; P128-A132 PolarHBondContact O-N 2.95Å; T129-A132 PolarHBondContact O-N 2.95Å; S130-A132 PolarHBondContact O-N 3.38Å; A132-I134 PolarHBondContact O-N 3.32Å; A132-A135 PolarHBondContact O-N 3.06Å; A132-I136 VanDerWaalsContact O-CD1 3.28Å; A132-I136 WeakPolarHBondContact O-CD1 3.46Å; A132-I136 WeakPolarHBondContact O-CG1 3.3Å; A132-I136 PolarHBondContact O-N 3.24Å; A132-L372 HydrophobicContact CB-CD2 4.07Å; A132-L380 HydrophobicContact CB-CD1 4.17Å
133	V	94.6	Very high	92.9	Very high	0 Å²	0	10.4 Å²	10.4	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-59.6	-46.2	176.6	173.1	0	0	0	0	111.1	T129 S130 A135 I136 T137 F236 V377 L380 I381	T129-V133 WeakPolarHBondContact O-CG2 3.4Å; T129-V133 PolarHBondContact O-N 3.1Å; S130-V133 PolarHBondContact O-N 3.38Å; V133-A135 PolarHBondContact O-N 3.41Å; V133-I136 PolarHBondContact O-N 3.49Å; V133-T137 WeakPolarHBondContact O-CB 3.48Å; V133-T137 PolarHBondContact O-N 3.25Å; V133-T137 PolarHBondContact O-OG1 3.45Å; V133-F236 HydrophobicContact CB-CZ 3.99Å; V133-F236 HydrophobicContact CG1-CE1 3.67Å; V133-F236 HydrophobicContact CG1-CE2 4.43Å; V133-F236 HydrophobicContact CG1-CZ 3.48Å; V133-F236 VanDerWaalsContact CG1-CZ 3.48Å; V133-V377 HydrophobicContact CB-CG1 4.39Å; V133-V377 HydrophobicContact CG1-CG1 3.83Å; V133-V377 HydrophobicContact CG2-CG1 4.13Å; V133-L380 HydrophobicContact CG2-CB 3.5Å; V133-L380 VanDerWaalsContact CG2-CB 3.5Å; V133-L380 HydrophobicContact CG2-CD1 4.12Å; V133-L380 HydrophobicContact CG2-CG 4.46Å; V133-I381 HydrophobicContact CG1-CD1 4.32Å; V133-I381 HydrophobicContact CG1-CG1 4.09Å; V133-I381 HydrophobicContact CG2-CG1 4.06Å
134	I	93.5	Very high	92.6	Very high	13 Å²	13	11.9 Å²	11.9	7%	0.067	6%	0.061	C	C	.	.	H	α-helix	trans	-61.8	-43.8	177.9	-60.7	159.6	0	0	0	110.8	S52 S130 Q131 A132 T137 F138 C319 L323	S52-I134 VanDerWaalsContact OG-CG1 3.31Å; S52-I134 WeakPolarHBondContact OG-CG1 3.43Å; S130-I134 WeakPolarHBondContact O-CD1 3.31Å; S130-I134 VanDerWaalsContact O-CG1 3.24Å; S130-I134 WeakPolarHBondContact O-CG1 3.14Å; S130-I134 PolarHBondContact O-N 3.46Å; Q131-I134 PolarHBondContact O-N 2.93Å; A132-I134 PolarHBondContact O-N 3.32Å; I134-T137 WeakPolarHBondContact O-CB 3.4Å; I134-T137 PolarHBondContact O-N 3.39Å; I134-F138 PolarHBondContact O-N 3.02Å; I134-C319 HydrophobicContact CG2-CB 3.98Å; I134-C319 WeakPolarHBondContact CG2-O 3.24Å; I134-L323 HydrophobicContact CG2-CB 3.81Å
135	A	95.5	Very high	92.2	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-66.7	-39	-179.9	0	0	0	0	0	112.9	Q131 A132 V133 T137 F138 S139 A161 I165 L323 L372	Q131-A135 VanDerWaalsContact O-CB 3.32Å; Q131-A135 WeakPolarHBondContact O-CB 3.15Å; Q131-A135 PolarHBondContact O-N 3.16Å; A132-A135 PolarHBondContact O-N 3.06Å; V133-A135 PolarHBondContact O-N 3.41Å; A135-T137 VanDerWaalsContact C-N 3.34Å; A135-F138 WeakPolarHBondContact O-CB 3.47Å; A135-F138 PolarHBondContact O-N 3.25Å; A135-S139 PolarHBondContact O-N 3.29Å; A135-S139 VanDerWaalsContact O-N 3.08Å; A135-A161 HydrophobicContact CB-CB 4.04Å; A135-A161 WeakPolarHBondContact O-CB 3.28Å; A135-I165 HydrophobicContact CB-CD1 3.74Å; A135-I165 HydrophobicContact CB-CG1 3.67Å; A135-L323 HydrophobicContact CB-CD2 3.97Å; A135-L372 HydrophobicContact CB-CD2 4.5Å
136	I	94.8	Very high	91.9	Very high	3 Å²	3	19.3 Å²	19.3	2%	0.015	10%	0.102	C	C	.	.	H	α-helix	trans	-66.4	-40.9	174.7	-62.3	155.4	0	0	0	110	A132 V133 S139 N140 L372 V377 L380	A132-I136 VanDerWaalsContact O-CD1 3.28Å; A132-I136 WeakPolarHBondContact O-CD1 3.46Å; A132-I136 WeakPolarHBondContact O-CG1 3.3Å; A132-I136 PolarHBondContact O-N 3.24Å; V133-I136 PolarHBondContact O-N 3.49Å; I136-S139 PolarHBondContact O-N 3.13Å; I136-N140 PolarHBondContact O-N 3.24Å; I136-L372 HydrophobicContact CD1-CD2 3.96Å; I136-L372 HydrophobicContact CG1-CD2 3.6Å; I136-V377 HydrophobicContact CB-CG2 4.14Å; I136-V377 HydrophobicContact CD1-CG2 3.98Å; I136-V377 HydrophobicContact CG2-CG2 3.46Å; I136-V377 VanDerWaalsContact CG2-CG2 3.46Å; I136-L380 HydrophobicContact CD1-CD1 3.72Å
137	T	92.8	Very high	91.6	Very high	1 Å²	1	22.1 Å²	22.1	1%	0.006	12%	0.115	C	C	.	.	H	α-helix	trans	-60.2	-48.2	175.3	-48.7	0	0	0	0	110.9	F55 V56 V133 I134 A135 S139 N140 Y141	F55-T137 HydrophobicContact CB-CG2 4.46Å; V56-T137 HydrophobicContact CG2-CG2 3.48Å; V56-T137 VanDerWaalsContact CG2-CG2 3.48Å; V56-T137 WeakPolarHBondContact CG2-OG1 3.16Å; V133-T137 WeakPolarHBondContact O-CB 3.48Å; V133-T137 PolarHBondContact O-N 3.25Å; V133-T137 PolarHBondContact O-OG1 3.45Å; I134-T137 WeakPolarHBondContact O-CB 3.4Å; I134-T137 PolarHBondContact O-N 3.39Å; A135-T137 VanDerWaalsContact C-N 3.34Å; T137-S139 PolarHBondContact O-N 3.2Å; T137-N140 PolarHBondContact O-N 3.42Å; T137-Y141 HydrophobicContact CG2-CD2 3.82Å; T137-Y141 HydrophobicContact CG2-CE2 3.89Å; T137-Y141 VanDerWaalsContact O-CD2 3.26Å; T137-Y141 WeakPolarHBondContact O-CD2 3.15Å; T137-Y141 PolarHBondContact O-N 2.85Å; T137-Y141 VanDerWaalsContact O-N 3.1Å
138	F	93.6	Very high	90.8	Very high	27 Å²	27	24.7 Å²	24.7	12%	0.118	13%	0.134	C	C	.	.	H	α-helix	trans	-50.5	-49	174.6	165.4	-97.6	0	0	0	111.3	I134 A135 Y141 M142 L160 C164 A316 C319	I134-F138 PolarHBondContact O-N 3.02Å; A135-F138 WeakPolarHBondContact O-CB 3.47Å; A135-F138 PolarHBondContact O-N 3.25Å; F138-Y141 PolarHBondContact O-N 3.27Å; F138-M142 HydrophobicContact CD2-CG 4.34Å; F138-M142 HydrophobicContact CE1-CG 4.28Å; F138-M142 HydrophobicContact CE2-CG 3.94Å; F138-M142 HydrophobicContact CE2-SD 4.34Å; F138-M142 HydrophobicContact CZ-CG 3.9Å; F138-M142 HydrophobicContact CZ-SD 4.43Å; F138-M142 VanDerWaalsContact O-CG 3.29Å; F138-M142 WeakPolarHBondContact O-CG 3.43Å; F138-M142 PolarHBondContact O-N 3.32Å; F138-M142 VanDerWaalsContact O-N 3.11Å; F138-L160 HydrophobicContact CE1-CD1 4.34Å; F138-L160 HydrophobicContact CE1-CG 4.2Å; F138-C164 HydrophobicContact CD1-CB 3.76Å; F138-C164 HydrophobicContact CE1-CB 3.74Å; F138-A316 HydrophobicContact CD2-CB 3.84Å; F138-A316 WeakPolarHBondContact CD2-O 3.49Å; F138-A316 HydrophobicContact CE2-CB 3.89Å; F138-C319 HydrophobicContact CB-CB 3.66Å; F138-C319 HydrophobicContact CD2-CB 4.47Å
139	S	94.3	Very high	90.1	Very high	0 Å²	0	31.4 Å²	31.4	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-70.5	-43.2	-176.1	-176.2	0	0	0	0	112.9	A135 I136 T137 Y141 M142 V143 N157 L160	A135-S139 PolarHBondContact O-N 3.29Å; A135-S139 VanDerWaalsContact O-N 3.08Å; I136-S139 PolarHBondContact O-N 3.13Å; T137-S139 PolarHBondContact O-N 3.2Å; S139-Y141 VanDerWaalsContact C-N 3.25Å; S139-Y141 PolarHBondContact O-N 2.99Å; S139-M142 PolarHBondContact O-N 2.93Å; S139-M142 VanDerWaalsContact O-N 3.1Å; S139-V143 WeakPolarHBondContact O-CB 3.47Å; S139-V143 VanDerWaalsContact O-CG2 3.29Å; S139-V143 WeakPolarHBondContact O-CG2 3.47Å; S139-V143 PolarHBondContact O-N 2.69Å; S139-N157 VanDerWaalsContact C-OD1 3.28Å; S139-N157 WeakPolarHBondContact CB-O 3.12Å; S139-N157 WeakPolarHBondContact CB-OD1 3.45Å; S139-N157 WeakPolarHBondContact OG-CA 3.49Å; S139-N157 PolarHBondContact OG-O 3.4Å; S139-N157 PolarHBondContact OG-OD1 3.46Å; S139-L160 WeakPolarHBondContact OG-CB 3.3Å; S139-L160 WeakPolarHBondContact OG-CD2 3.45Å
140	N	91.3	Very high	89.5	Confident	24 Å²	24	34.7 Å²	34.7	13%	0.128	20%	0.197	C	C	.	.	H	α-helix	trans	-53.1	-46.6	174.2	-76.6	-1.7	0	0	0	111.1	I136 T137 M142 V143 Q144 N157	I136-N140 PolarHBondContact O-N 3.24Å; T137-N140 PolarHBondContact O-N 3.42Å; N140-M142 VanDerWaalsContact C-N 3.35Å; N140-M142 PolarHBondContact O-N 3.44Å; N140-V143 PolarHBondContact O-N 2.96Å; N140-Q144 WeakPolarHBondContact O-CB 3.26Å; N140-Q144 PolarHBondContact O-N 3.47Å; N140-N157 PolarHBondContact N-OD1 2.95Å; N140-N157 PolarHBondContact OD1-ND2 2.98Å; N140-N157 PolarHBondContact OD1-OD1 3.45Å
141	Y	90.8	Very high	88.9	Confident	0 Å²	0	41.4 Å²	41.4	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-70.8	-27.3	-178.6	-86.4	-96.2	0	0	0	113.8	F55 T137 F138 S139 P145 A294 V295 A296 V297 P312 V315	F55-Y141 HydrophobicContact CB-CE2 3.87Å; F55-Y141 WeakPolarHBondContact CB-OH 3.41Å; F55-Y141 PolarHBondContact O-OH 3.25Å; F55-Y141 VanDerWaalsContact O-OH 3.08Å; T137-Y141 HydrophobicContact CG2-CD2 3.82Å; T137-Y141 HydrophobicContact CG2-CE2 3.89Å; T137-Y141 VanDerWaalsContact O-CD2 3.26Å; T137-Y141 WeakPolarHBondContact O-CD2 3.15Å; T137-Y141 PolarHBondContact O-N 2.85Å; T137-Y141 VanDerWaalsContact O-N 3.1Å; F138-Y141 PolarHBondContact O-N 3.27Å; S139-Y141 VanDerWaalsContact C-N 3.25Å; S139-Y141 PolarHBondContact O-N 2.99Å; Y141-P145 WeakPolarHBondContact O-CD 3.48Å; Y141-A294 HydrophobicContact CD1-CB 4.05Å; Y141-A294 HydrophobicContact CD2-CB 3.89Å; Y141-A294 HydrophobicContact CE1-CB 3.89Å; Y141-A294 HydrophobicContact CE2-CB 3.74Å; Y141-A294 HydrophobicContact CG-CB 4.06Å; Y141-V295 PolarHBondContact OH-N 3.26Å; Y141-A296 HydrophobicContact CE1-CB 3.93Å; Y141-A296 PolarHBondContact OH-N 3.45Å; Y141-V297 HydrophobicContact CD1-CG2 3.54Å; Y141-V297 HydrophobicContact CE1-CG2 3.71Å; Y141-P312 WeakPolarHBondContact O-CB 3.13Å; Y141-V315 HydrophobicContact CD1-CB 3.51Å; Y141-V315 HydrophobicContact CD1-CG1 3.4Å; Y141-V315 VanDerWaalsContact CD1-CG1 3.4Å; Y141-V315 HydrophobicContact CD1-CG2 3.96Å; Y141-V315 HydrophobicContact CD2-CG1 3.88Å; Y141-V315 HydrophobicContact CE1-CB 3.83Å; Y141-V315 HydrophobicContact CE1-CG1 3.58Å; Y141-V315 HydrophobicContact CE1-CG2 3.8Å; Y141-V315 HydrophobicContact CE2-CG1 4.04Å; Y141-V315 HydrophobicContact CG-CB 4.05Å; Y141-V315 HydrophobicContact CG-CG1 3.55Å
142	M	90.9	Very high	88.4	Confident	58 Å²	58	42.6 Å²	42.6	29%	0.286	24%	0.24	S	C	.	.	H	α-helix	trans	-79.5	-32.3	174.7	-70.2	-78.9	75.4	0	0	113.1	F138 S139 N140 L160 A316	F138-M142 HydrophobicContact CD2-CG 4.34Å; F138-M142 HydrophobicContact CE1-CG 4.28Å; F138-M142 HydrophobicContact CE2-CG 3.94Å; F138-M142 HydrophobicContact CE2-SD 4.34Å; F138-M142 HydrophobicContact CZ-CG 3.9Å; F138-M142 HydrophobicContact CZ-SD 4.43Å; F138-M142 VanDerWaalsContact O-CG 3.29Å; F138-M142 WeakPolarHBondContact O-CG 3.43Å; F138-M142 PolarHBondContact O-N 3.32Å; F138-M142 VanDerWaalsContact O-N 3.11Å; S139-M142 PolarHBondContact O-N 2.93Å; S139-M142 VanDerWaalsContact O-N 3.1Å; N140-M142 VanDerWaalsContact C-N 3.35Å; N140-M142 PolarHBondContact O-N 3.44Å; M142-L160 HydrophobicContact CB-CD2 3.94Å; M142-A316 HydrophobicContact CE-CB 3.43Å; M142-A316 VanDerWaalsContact CE-CB 3.43Å; M142-A316 HydrophobicContact CG-CB 3.73Å; M142-A316 HydrophobicContact SD-CB 3.58Å; M142-A316 VanDerWaalsContact SD-CB 3.58Å
143	V	90.5	Very high	88.1	Confident	12 Å²	12	45.6 Å²	45.6	7%	0.073	26%	0.259	C	S	.	.	H	α-helix	trans	-87.6	-32.1	-176.3	-178	0	0	0	0	111.7	S139 N140 P145 I146 F147 A152 L160	S139-V143 WeakPolarHBondContact O-CB 3.47Å; S139-V143 VanDerWaalsContact O-CG2 3.29Å; S139-V143 WeakPolarHBondContact O-CG2 3.47Å; S139-V143 PolarHBondContact O-N 2.69Å; N140-V143 PolarHBondContact O-N 2.96Å; V143-P145 VanDerWaalsContact C-CD 3.48Å; V143-I146 WeakPolarHBondContact O-CB 3.35Å; V143-I146 PolarHBondContact O-N 3.09Å; V143-F147 HydrophobicContact CG1-CD2 3.31Å; V143-F147 HydrophobicContact CG1-CE2 3.63Å; V143-F147 HydrophobicContact CG1-CG 4.33Å; V143-F147 PolarHBondContact O-N 3.24Å; V143-F147 VanDerWaalsContact O-N 3.13Å; V143-A152 HydrophobicContact CB-CB 4.43Å; V143-A152 HydrophobicContact CG1-CB 3.49Å; V143-A152 VanDerWaalsContact CG1-CB 3.49Å; V143-L160 HydrophobicContact CG2-CD2 3.82Å
144	Q	84.9	Confident	87.8	Confident	36 Å²	36	50 Å²	50	17%	0.168	28%	0.277	C	S	.	.	T	Hydrogen-bonded Turn	trans	-50.7	-44.9	-178.5	-169.3	70.9	15.2	0	0	114.1	N140 I146 F147 A294 V297	N140-Q144 WeakPolarHBondContact O-CB 3.26Å; N140-Q144 PolarHBondContact O-N 3.47Å; Q144-I146 PolarHBondContact O-N 2.9Å; Q144-F147 CarbonylContact O-C 3.32Å; Q144-F147 PolarHBondContact O-N 3.46Å; Q144-A294 HydrophobicContact CB-CB 4.11Å; Q144-A294 HydrophobicContact CG-CB 4.1Å; Q144-V297 HydrophobicContact CB-CG1 4.37Å; Q144-V297 HydrophobicContact CG-CB 4.15Å; Q144-V297 HydrophobicContact CG-CG1 3.85Å
145	P	83.7	Confident	87.7	Confident	61 Å²	61	54.1 Å²	54.1	40%	0.396	30%	0.302	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.3	-22.7	179.9	-21.4	35.7	0	0	0	113.9	Y141 V143 P312	Y141-P145 WeakPolarHBondContact O-CD 3.48Å; V143-P145 VanDerWaalsContact C-CD 3.48Å; P145-P312 HydrophobicContact CG-CB 3.64Å; P145-P312 HydrophobicContact CG-CG 3.6Å
146	I	86.3	Confident	87.4	Confident	123 Å²	123	56.3 Å²	56.3	63%	0.631	32%	0.32	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.3	-30.8	178.8	-55.4	172.1	0	0	0	110.4	V143 Q144 P148	V143-I146 WeakPolarHBondContact O-CB 3.35Å; V143-I146 PolarHBondContact O-N 3.09Å; Q144-I146 PolarHBondContact O-N 2.9Å; I146-P148 VanDerWaalsContact O-CD 3.28Å; I146-P148 WeakPolarHBondContact O-CD 3.44Å
147	F	85.2	Confident	87.3	Confident	63 Å²	63	56.9 Å²	56.9	28%	0.276	32%	0.323	S	S	.	.	S	Bend	trans	-119.4	61.5	180	-61.3	-95.6	0	0	0	111.1	V143 Q144 T149 C150 P153	V143-F147 HydrophobicContact CG1-CD2 3.31Å; V143-F147 HydrophobicContact CG1-CE2 3.63Å; V143-F147 HydrophobicContact CG1-CG 4.33Å; V143-F147 PolarHBondContact O-N 3.24Å; V143-F147 VanDerWaalsContact O-N 3.13Å; Q144-F147 CarbonylContact O-C 3.32Å; Q144-F147 PolarHBondContact O-N 3.46Å; F147-T149 VanDerWaalsContact C-N 3.3Å; F147-T149 PolarHBondContact O-N 2.93Å; F147-C150 VanDerWaalsContact O-O 3.05Å; F147-P153 HydrophobicContact CE1-CG 4.32Å; F147-P153 HydrophobicContact CZ-CG 4.38Å
148	P	74.9	Confident	87.3	Confident	81 Å²	81	57.9 Å²	57.9	53%	0.526	33%	0.327	S	S	.	.	S	Bend	trans	-69.8	-24.6	-172.3	27.9	-35.8	0	0	0	113.9	I146	I146-P148 VanDerWaalsContact O-CD 3.28Å; I146-P148 WeakPolarHBondContact O-CD 3.44Å
149	T	77.4	Confident	87.4	Confident	140 Å²	140	62.1 Å²	62.1	86%	0.859	35%	0.35	S	S	*	.	S	Bend	trans	-118.1	0.1	-174.3	54.3	0	0	0	0	113.7	F147	F147-T149 VanDerWaalsContact C-N 3.3Å; F147-T149 PolarHBondContact O-N 2.93Å
150	C	82	Confident	87.4	Confident	70 Å²	70	65 Å²	65	47%	0.473	37%	0.365	S	S	.	.	S	Bend	trans	-139.7	157.9	-175.8	54.1	0	0	0	0	111.3	F147 A152	F147-C150 VanDerWaalsContact O-O 3.05Å; C150-A152 PolarHBondContact O-N 3.31Å
151	I	79.6	Confident	87.7	Confident	158 Å²	158	63.9 Å²	63.9	81%	0.81	36%	0.359	S	S	*	.	P	Polyproline II helix	trans	-72.2	123.2	-178.4	-57.4	171	0	0	0	108.5
152	A	83.9	Confident	88	Confident	24 Å²	24	64.9 Å²	64.9	20%	0.198	37%	0.368	C	S	.	.	P	Polyproline II helix	trans	-57.3	135	174.9	0	0	0	0	0	110.9	V143 C150 Y154	V143-A152 HydrophobicContact CB-CB 4.43Å; V143-A152 HydrophobicContact CG1-CB 3.49Å; V143-A152 VanDerWaalsContact CG1-CB 3.49Å; C150-A152 PolarHBondContact O-N 3.31Å; A152-Y154 PolarHBondContact O-N 3.21Å; A152-Y154 VanDerWaalsContact O-N 3.14Å
153	P	89.5	Confident	88.2	Confident	63 Å²	63	64.7 Å²	64.7	41%	0.409	38%	0.375	S	S	.	.	P	Polyproline II helix	trans	-59.5	121.3	177.8	-23	32.3	0	0	0	111.4	F147 V155 A156 N157	F147-P153 HydrophobicContact CE1-CG 4.32Å; F147-P153 HydrophobicContact CZ-CG 4.38Å; P153-V155 VanDerWaalsContact C-N 3.27Å; P153-V155 PolarHBondContact O-N 3.46Å; P153-A156 HydrophobicContact CB-CB 4.1Å; P153-A156 PolarHBondContact O-N 3.36Å; P153-A156 VanDerWaalsContact O-N 3.08Å; P153-N157 PolarHBondContact O-N 3.28Å; P153-N157 VanDerWaalsContact O-N 3.09Å
154	Y	89.2	Confident	88.5	Confident	94 Å²	94	64.4 Å²	64.4	37%	0.369	37%	0.374	S	S	.	.	H	α-helix	trans	-51.2	-45.7	-177.5	173.1	-94.8	0	0	0	112.5	A152 A156 N157 R158 E375	A152-Y154 PolarHBondContact O-N 3.21Å; A152-Y154 VanDerWaalsContact O-N 3.14Å; Y154-A156 PolarHBondContact O-N 3Å; Y154-N157 WeakPolarHBondContact O-CB 3.35Å; Y154-N157 PolarHBondContact O-N 2.83Å; Y154-R158 HydrophobicContact CD1-CG 4.21Å; Y154-R158 HydrophobicContact CD2-CG 4.31Å; Y154-R158 HydrophobicContact CE1-CG 3.75Å; Y154-R158 HydrophobicContact CE2-CG 3.87Å; Y154-R158 VanDerWaalsContact CE2-NE 3.32Å; Y154-R158 HydrophobicContact CG-CG 4.46Å; Y154-R158 WeakPolarHBondContact O-CG 3.44Å; Y154-R158 PolarHBondContact O-N 3.03Å; Y154-R158 PolarHBondContact OH-NE 2.92Å; Y154-E375 HydrophobicContact CE2-CB 4.33Å; Y154-E375 HydrophobicContact CE2-CG 4.28Å
155	V	90.4	Very high	89	Confident	98 Å²	98	62.8 Å²	62.8	59%	0.594	37%	0.366	S	S	*	.	H	α-helix	trans	-64.4	-42.2	-178.5	-179.2	0	0	0	0	111.8	P153 N157 R158 L159	P153-V155 VanDerWaalsContact C-N 3.27Å; P153-V155 PolarHBondContact O-N 3.46Å; V155-N157 VanDerWaalsContact C-N 3.33Å; V155-N157 PolarHBondContact O-N 2.91Å; V155-R158 PolarHBondContact O-N 3.13Å; V155-L159 HydrophobicContact CG1-CD1 3.89Å; V155-L159 HydrophobicContact CG1-CG 4.24Å; V155-L159 WeakPolarHBondContact O-CB 3.44Å; V155-L159 VanDerWaalsContact O-CG 3.27Å; V155-L159 WeakPolarHBondContact O-CG 3.24Å; V155-L159 PolarHBondContact O-N 3.3Å
156	A	90.1	Very high	89.6	Confident	47 Å²	47	62.9 Å²	62.9	39%	0.388	37%	0.368	S	S	.	.	H	α-helix	trans	-63.5	-42.7	178.6	0	0	0	0	0	111.1	P153 Y154 L159 L160	P153-A156 HydrophobicContact CB-CB 4.1Å; P153-A156 PolarHBondContact O-N 3.36Å; P153-A156 VanDerWaalsContact O-N 3.08Å; Y154-A156 PolarHBondContact O-N 3Å; A156-L159 PolarHBondContact O-N 3.24Å; A156-L160 WeakPolarHBondContact O-CB 3.45Å; A156-L160 PolarHBondContact O-N 3.43Å
157	N	91.1	Very high	89.9	Confident	15 Å²	15	61.3 Å²	61.3	8%	0.08	36%	0.36	C	S	.	.	H	α-helix	trans	-61.2	-45.2	175.8	-173.3	30.5	0	0	0	111.8	S139 N140 P153 Y154 V155 L160 A161	S139-N157 VanDerWaalsContact C-OD1 3.28Å; S139-N157 WeakPolarHBondContact CB-O 3.12Å; S139-N157 WeakPolarHBondContact CB-OD1 3.45Å; S139-N157 WeakPolarHBondContact OG-CA 3.49Å; S139-N157 PolarHBondContact OG-O 3.4Å; S139-N157 PolarHBondContact OG-OD1 3.46Å; N140-N157 PolarHBondContact N-OD1 2.95Å; N140-N157 PolarHBondContact OD1-ND2 2.98Å; N140-N157 PolarHBondContact OD1-OD1 3.45Å; P153-N157 PolarHBondContact O-N 3.28Å; P153-N157 VanDerWaalsContact O-N 3.09Å; Y154-N157 WeakPolarHBondContact O-CB 3.35Å; Y154-N157 PolarHBondContact O-N 2.83Å; V155-N157 VanDerWaalsContact C-N 3.33Å; V155-N157 PolarHBondContact O-N 2.91Å; N157-L160 PolarHBondContact O-N 3.49Å; N157-A161 PolarHBondContact O-N 3.35Å
158	R	93.8	Very high	90.2	Very high	22 Å²	22	58.4 Å²	58.4	8%	0.083	35%	0.347	C	S	.	.	H	α-helix	trans	-68.4	-37.6	177.9	-65.9	-61.2	174.6	147.4	-8.9	113.4	Y154 V155 A161 A162 L372 V374 E375	Y154-R158 HydrophobicContact CD1-CG 4.21Å; Y154-R158 HydrophobicContact CD2-CG 4.31Å; Y154-R158 HydrophobicContact CE1-CG 3.75Å; Y154-R158 HydrophobicContact CE2-CG 3.87Å; Y154-R158 VanDerWaalsContact CE2-NE 3.32Å; Y154-R158 HydrophobicContact CG-CG 4.46Å; Y154-R158 WeakPolarHBondContact O-CG 3.44Å; Y154-R158 PolarHBondContact O-N 3.03Å; Y154-R158 PolarHBondContact OH-NE 2.92Å; V155-R158 PolarHBondContact O-N 3.13Å; R158-A161 PolarHBondContact O-N 2.98Å; R158-A162 WeakPolarHBondContact O-CB 2.86Å; R158-A162 PolarHBondContact O-N 2.81Å; R158-L372 PolarHBondContact NH1-O 2.81Å; R158-V374 PolarHBondContact NH1-O 3.1Å; R158-V374 PolarHBondContact NH2-O 3.39Å; R158-E375 VanDerWaalsContact NH2-C 3.35Å; R158-E375 PolarHBondContact NH2-O 2.8Å
159	L	95	Very high	91	Very high	115 Å²	115	55 Å²	55	60%	0.602	33%	0.325	S	S	*	.	H	α-helix	trans	-66.3	-37.8	175.7	-72.7	174.7	0	0	0	112	V155 A156 A162 A163	V155-L159 HydrophobicContact CG1-CD1 3.89Å; V155-L159 HydrophobicContact CG1-CG 4.24Å; V155-L159 WeakPolarHBondContact O-CB 3.44Å; V155-L159 VanDerWaalsContact O-CG 3.27Å; V155-L159 WeakPolarHBondContact O-CG 3.24Å; V155-L159 PolarHBondContact O-N 3.3Å; A156-L159 PolarHBondContact O-N 3.24Å; L159-A162 PolarHBondContact O-N 2.65Å; L159-A163 WeakPolarHBondContact O-CB 3.34Å; L159-A163 PolarHBondContact O-N 3.44Å
160	L	95.4	Very high	91.7	Very high	62 Å²	62	55 Å²	55	33%	0.325	31%	0.313	S	S	.	.	H	α-helix	trans	-68	-41.1	175.3	179.5	62.7	0	0	0	111.7	F138 S139 M142 V143 A156 N157 A163 C164	F138-L160 HydrophobicContact CE1-CD1 4.34Å; F138-L160 HydrophobicContact CE1-CG 4.2Å; S139-L160 WeakPolarHBondContact OG-CB 3.3Å; S139-L160 WeakPolarHBondContact OG-CD2 3.45Å; M142-L160 HydrophobicContact CB-CD2 3.94Å; V143-L160 HydrophobicContact CG2-CD2 3.82Å; A156-L160 WeakPolarHBondContact O-CB 3.45Å; A156-L160 PolarHBondContact O-N 3.43Å; N157-L160 PolarHBondContact O-N 3.49Å; L160-A163 PolarHBondContact O-N 3.26Å; L160-C164 PolarHBondContact O-N 2.87Å
161	A	96.2	Very high	91.9	Very high	0 Å²	0	53.7 Å²	53.7	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-59.5	-45.6	171.2	0	0	0	0	0	111.9	A135 N157 R158 C164 I165 L372	A135-A161 HydrophobicContact CB-CB 4.04Å; A135-A161 WeakPolarHBondContact O-CB 3.28Å; N157-A161 PolarHBondContact O-N 3.35Å; R158-A161 PolarHBondContact O-N 2.98Å; A161-C164 WeakPolarHBondContact O-CB 3.33Å; A161-C164 PolarHBondContact O-N 2.96Å; A161-I165 PolarHBondContact O-N 3.15Å; A161-L372 HydrophobicContact CB-CD1 4.17Å; A161-L372 HydrophobicContact CB-CD2 4.03Å
162	A	97	Very high	92.3	Very high	21 Å²	21	46.2 Å²	46.2	17%	0.174	27%	0.265	C	S	.	.	H	α-helix	trans	-62.9	-42.3	176.9	0	0	0	0	0	112.2	R158 L159 C164 I165 C166 L369 L372	R158-A162 WeakPolarHBondContact O-CB 2.86Å; R158-A162 PolarHBondContact O-N 2.81Å; L159-A162 PolarHBondContact O-N 2.65Å; A162-C164 VanDerWaalsContact C-N 3.29Å; A162-C164 PolarHBondContact O-N 2.92Å; A162-I165 PolarHBondContact O-N 3.23Å; A162-C166 WeakPolarHBondContact O-CB 3.15Å; A162-C166 PolarHBondContact O-N 3.44Å; A162-C166 PolarHBondContact O-SG 2.77Å; A162-C166 VanDerWaalsContact O-SG 3.4Å; A162-L369 HydrophobicContact CB-CD2 3.72Å; A162-L372 HydrophobicContact CB-CD1 3.72Å
163	A	96.9	Very high	92.4	Very high	54 Å²	54	45.7 Å²	45.7	45%	0.446	26%	0.259	S	S	.	.	H	α-helix	trans	-60.8	-40	175.4	0	0	0	0	0	111.5	L159 L160 C166 L167	L159-A163 WeakPolarHBondContact O-CB 3.34Å; L159-A163 PolarHBondContact O-N 3.44Å; L160-A163 PolarHBondContact O-N 3.26Å; A163-C166 PolarHBondContact O-N 2.95Å; A163-L167 WeakPolarHBondContact O-CB 3.36Å; A163-L167 PolarHBondContact O-N 3.45Å
164	C	95.1	Very high	92.1	Very high	6 Å²	6	44 Å²	44	4%	0.041	25%	0.251	C	S	.	.	H	α-helix	trans	-63	-47.2	176.1	-170.4	0	0	0	0	112	F138 L160 A161 A162 L167 L168	F138-C164 HydrophobicContact CD1-CB 3.76Å; F138-C164 HydrophobicContact CE1-CB 3.74Å; L160-C164 PolarHBondContact O-N 2.87Å; A161-C164 WeakPolarHBondContact O-CB 3.33Å; A161-C164 PolarHBondContact O-N 2.96Å; A162-C164 VanDerWaalsContact C-N 3.29Å; A162-C164 PolarHBondContact O-N 2.92Å; C164-L167 PolarHBondContact O-N 2.8Å; C164-L168 WeakPolarHBondContact O-CB 3.47Å; C164-L168 PolarHBondContact O-N 3.38Å
165	I	95.8	Very high	91.4	Very high	1 Å²	1	44.7 Å²	44.7	1%	0.005	25%	0.254	C	S	.	.	H	α-helix	trans	-59.1	-53	175	-65.4	175.6	0	0	0	110.2	A135 A161 A162 L167 L168 T169 L323 A368 L369 L372	A135-I165 HydrophobicContact CB-CD1 3.74Å; A135-I165 HydrophobicContact CB-CG1 3.67Å; A161-I165 PolarHBondContact O-N 3.15Å; A162-I165 PolarHBondContact O-N 3.23Å; I165-L167 VanDerWaalsContact C-N 3.31Å; I165-L167 PolarHBondContact O-N 3.07Å; I165-L168 PolarHBondContact O-N 2.85Å; I165-T169 WeakPolarHBondContact O-CB 3.38Å; I165-T169 PolarHBondContact O-N 3.35Å; I165-T169 PolarHBondContact O-OG1 3.46Å; I165-L323 HydrophobicContact CG1-CD2 3.99Å; I165-A368 HydrophobicContact CD1-CB 3.96Å; I165-A368 HydrophobicContact CG2-CB 4.32Å; I165-L369 HydrophobicContact CB-CD2 4.47Å; I165-L369 HydrophobicContact CG2-CD2 4.46Å; I165-L372 HydrophobicContact CD1-CD1 3.83Å; I165-L372 HydrophobicContact CD1-CD2 4.39Å; I165-L372 HydrophobicContact CD1-CG 4.12Å
166	C	96	Very high	90.2	Very high	64 Å²	64	42.4 Å²	42.4	43%	0.432	24%	0.24	S	C	.	.	H	α-helix	trans	-59.8	-41	-178.8	-72.2	0	0	0	0	112.5	A162 A163 F170	A162-C166 WeakPolarHBondContact O-CB 3.15Å; A162-C166 PolarHBondContact O-N 3.44Å; A162-C166 PolarHBondContact O-SG 2.77Å; A162-C166 VanDerWaalsContact O-SG 3.4Å; A163-C166 PolarHBondContact O-N 2.95Å; C166-F170 VanDerWaalsContact O-CB 3.27Å; C166-F170 WeakPolarHBondContact O-CB 3.29Å; C166-F170 PolarHBondContact O-N 2.96Å
167	L	93.4	Very high	88.9	Confident	90 Å²	90	46.3 Å²	46.3	47%	0.471	25%	0.248	S	C	.	.	H	α-helix	trans	-62.3	-49	177.1	177.5	63.4	0	0	0	110.9	A163 C164 I165 F170 V171 F320	A163-L167 WeakPolarHBondContact O-CB 3.36Å; A163-L167 PolarHBondContact O-N 3.45Å; C164-L167 PolarHBondContact O-N 2.8Å; I165-L167 VanDerWaalsContact C-N 3.31Å; I165-L167 PolarHBondContact O-N 3.07Å; L167-F170 WeakPolarHBondContact O-CB 3.39Å; L167-F170 PolarHBondContact O-N 3.21Å; L167-V171 HydrophobicContact CD1-CG2 4.42Å; L167-V171 VanDerWaalsContact O-CG2 3.3Å; L167-V171 WeakPolarHBondContact O-CG2 3.27Å; L167-V171 PolarHBondContact O-N 3.27Å; L167-F320 HydrophobicContact CD2-CE2 4.27Å
168	L	91.3	Very high	87.5	Confident	2 Å²	2	54 Å²	54	1%	0.01	28%	0.276	C	S	.	.	H	α-helix	trans	-67.8	-40	179.9	-77.8	175.6	0	0	0	112.4	C164 I165 F170 V171 N172 F320 L323 N324 I327	C164-L168 WeakPolarHBondContact O-CB 3.47Å; C164-L168 PolarHBondContact O-N 3.38Å; I165-L168 PolarHBondContact O-N 2.85Å; L168-F170 VanDerWaalsContact C-N 3.31Å; L168-F170 PolarHBondContact O-N 3.04Å; L168-V171 PolarHBondContact O-N 2.9Å; L168-N172 WeakPolarHBondContact O-CB 3.1Å; L168-N172 PolarHBondContact O-N 3.41Å; L168-N172 PolarHBondContact O-ND2 3.27Å; L168-F320 HydrophobicContact CD1-CD2 4.1Å; L168-F320 HydrophobicContact CD1-CE2 4.12Å; L168-F320 HydrophobicContact CD1-CG 4.36Å; L168-F320 HydrophobicContact CD1-CZ 4.41Å; L168-F320 HydrophobicContact CD2-CD1 4.1Å; L168-F320 HydrophobicContact CD2-CD2 4.39Å; L168-F320 HydrophobicContact CD2-CE1 3.46Å; L168-F320 VanDerWaalsContact CD2-CE1 3.46Å; L168-F320 HydrophobicContact CD2-CE2 3.78Å; L168-F320 HydrophobicContact CD2-CZ 3.27Å; L168-F320 HydrophobicContact CG-CD2 4.31Å; L168-F320 HydrophobicContact CG-CE1 4.36Å; L168-F320 HydrophobicContact CG-CE2 3.82Å; L168-F320 HydrophobicContact CG-CZ 3.86Å; L168-L323 HydrophobicContact CD1-CB 3.75Å; L168-L323 HydrophobicContact CD1-CD2 3.66Å; L168-L323 HydrophobicContact CD1-CG 3.58Å; L168-N324 HydrophobicContact CD1-CB 4.36Å; L168-N324 HydrophobicContact CD2-CB 3.98Å; L168-I327 HydrophobicContact CB-CD1 3.82Å
169	T	91.7	Very high	85.7	Confident	10 Å²	10	53.2 Å²	53.2	6%	0.061	27%	0.274	C	S	.	.	H	α-helix	trans	-59.3	-44.9	172.2	-58.3	0	0	0	0	110.4	I165 N172 C173 L361 L362	I165-T169 WeakPolarHBondContact O-CB 3.38Å; I165-T169 PolarHBondContact O-N 3.35Å; I165-T169 PolarHBondContact O-OG1 3.46Å; T169-N172 PolarHBondContact O-N 2.9Å; T169-C173 WeakPolarHBondContact O-CB 3.26Å; T169-C173 PolarHBondContact O-N 3.33Å; T169-C173 PolarHBondContact O-SG 3.24Å; T169-L361 HydrophobicContact CG2-CB 4.3Å; T169-L361 WeakPolarHBondContact CG2-O 3.44Å; T169-L362 HydrophobicContact CG2-CD2 4.4Å
170	F	91.4	Very high	83.9	Confident	138 Å²	138	50.8 Å²	50.8	61%	0.605	27%	0.265	S	S	*	.	H	α-helix	trans	-60.8	-46.6	176.5	175.1	-98.3	0	0	0	112.5	C166 L167 L168 N172 C173 A174	C166-F170 VanDerWaalsContact O-CB 3.27Å; C166-F170 WeakPolarHBondContact O-CB 3.29Å; C166-F170 PolarHBondContact O-N 2.96Å; L167-F170 WeakPolarHBondContact O-CB 3.39Å; L167-F170 PolarHBondContact O-N 3.21Å; L168-F170 VanDerWaalsContact C-N 3.31Å; L168-F170 PolarHBondContact O-N 3.04Å; F170-N172 VanDerWaalsContact C-N 3.34Å; F170-N172 PolarHBondContact O-N 3.23Å; F170-C173 PolarHBondContact O-N 3.25Å; F170-A174 WeakPolarHBondContact O-CB 3.39Å; F170-A174 PolarHBondContact O-N 2.68Å
171	V	88.1	Confident	82.3	Confident	44 Å²	44	56.8 Å²	56.8	27%	0.267	28%	0.283	S	S	.	.	H	α-helix	trans	-59.9	-44.4	178.1	170	0	0	0	0	111	L167 L168 A174 Y175	L167-V171 HydrophobicContact CD1-CG2 4.42Å; L167-V171 VanDerWaalsContact O-CG2 3.3Å; L167-V171 WeakPolarHBondContact O-CG2 3.27Å; L167-V171 PolarHBondContact O-N 3.27Å; L168-V171 PolarHBondContact O-N 2.9Å; V171-A174 PolarHBondContact O-N 2.61Å; V171-A174 VanDerWaalsContact O-N 3.15Å; V171-Y175 PolarHBondContact O-N 3.44Å
172	N	86.3	Confident	80.7	Confident	1 Å²	1	59.8 Å²	59.8	1%	0.005	30%	0.301	C	S	.	.	H	α-helix	trans	-68.9	-32.3	178.2	-77	-71.5	0	0	0	113	L168 T169 F170 A174 N324 I327 V328 L361	L168-N172 WeakPolarHBondContact O-CB 3.1Å; L168-N172 PolarHBondContact O-N 3.41Å; L168-N172 PolarHBondContact O-ND2 3.27Å; T169-N172 PolarHBondContact O-N 2.9Å; F170-N172 VanDerWaalsContact C-N 3.34Å; F170-N172 PolarHBondContact O-N 3.23Å; N172-A174 VanDerWaalsContact C-N 3.32Å; N172-N324 PolarHBondContact ND2-OD1 3.11Å; N172-N324 PolarHBondContact OD1-OD1 3.37Å; N172-I327 HydrophobicContact CB-CG2 4.45Å; N172-V328 WeakPolarHBondContact OD1-CG2 3.35Å; N172-L361 HydrophobicContact CB-CD1 4.01Å; N172-L361 HydrophobicContact CB-CD2 4.13Å
173	C	86	Confident	79	Confident	12 Å²	12	60.7 Å²	60.7	8%	0.081	30%	0.302	C	S	.	.	H	α-helix	trans	-67.8	-34	170.7	-71.3	0	0	0	0	111.9	T169 F170 T356 I358	T169-C173 WeakPolarHBondContact O-CB 3.26Å; T169-C173 PolarHBondContact O-N 3.33Å; T169-C173 PolarHBondContact O-SG 3.24Å; F170-C173 PolarHBondContact O-N 3.25Å; C173-T356 PolarHBondContact O-OG1 3.26Å; C173-I358 HydrophobicContact CB-CG1 4.18Å
174	A	83.8	Confident	77.4	Confident	28 Å²	28	63 Å²	63	23%	0.231	31%	0.306	C	S	.	.	H	α-helix	trans	-76.4	-55.2	-177.6	0	0	0	0	0	113.4	F170 V171 N172 R354	F170-A174 WeakPolarHBondContact O-CB 3.39Å; F170-A174 PolarHBondContact O-N 2.68Å; V171-A174 PolarHBondContact O-N 2.61Å; V171-A174 VanDerWaalsContact O-N 3.15Å; N172-A174 VanDerWaalsContact C-N 3.32Å; A174-R354 WeakPolarHBondContact O-CD 3.38Å
175	Y	75.4	Confident	76.2	Confident	108 Å²	108	69.4 Å²	69.4	42%	0.424	33%	0.334	S	S	.	.			trans	-160.5	106.6	-178.2	-163.3	-100.9	0	0	0	112.9	V171 K177 W178	V171-Y175 PolarHBondContact O-N 3.44Å; Y175-K177 VanDerWaalsContact C-N 3.32Å; Y175-K177 HydrophobicContact CD1-CB 4.03Å; Y175-K177 HydrophobicContact CE1-CB 3.55Å; Y175-K177 HydrophobicContact CE1-CD 4.21Å; Y175-K177 HydrophobicContact CE1-CG 4.05Å; Y175-K177 PolarHBondContact O-N 2.66Å; Y175-W178 AromaticContact CD1-CD1 3.17Å; Y175-W178 HydrophobicContact CD1-CG 4Å; Y175-W178 AromaticContact CD1-NE1 3.63Å; Y175-W178 AromaticContact CE1-CD1 3.57Å; Y175-W178 AromaticContact CE1-NE1 3.85Å; Y175-W178 PolarHBondContact O-N 3.36Å
176	V	63.6	Low	75	Confident	50 Å²	50	70.6 Å²	70.6	30%	0.303	34%	0.339	S	S	.	.	H	α-helix	trans	-61.2	-31.9	-173.4	167.5	0	0	0	0	113.8	W178 G179 T356	V176-W178 PolarHBondContact O-N 3.38Å; V176-G179 PolarHBondContact O-N 3.42Å; V176-T356 HydrophobicContact CB-CG2 4.34Å; V176-T356 HydrophobicContact CG2-CG2 3.46Å; V176-T356 VanDerWaalsContact CG2-CG2 3.46Å
177	K	64.4	Low	73.8	Confident	130 Å²	130	68.6 Å²	68.6	57%	0.565	33%	0.325	S	S	*	.	H	α-helix	trans	-72.9	-12.4	-176.5	-52.5	-177.9	178.2	176.9	0	114.2	Y175 T180	Y175-K177 VanDerWaalsContact C-N 3.32Å; Y175-K177 HydrophobicContact CD1-CB 4.03Å; Y175-K177 HydrophobicContact CE1-CB 3.55Å; Y175-K177 HydrophobicContact CE1-CD 4.21Å; Y175-K177 HydrophobicContact CE1-CG 4.05Å; Y175-K177 PolarHBondContact O-N 2.66Å; K177-T180 PolarHBondContact O-OG1 2.86Å
178	W	61.3	Low	72.9	Confident	177 Å²	177	71.5 Å²	71.5	67%	0.67	33%	0.331	S	S	*	.	H	α-helix	trans	-77.6	-36.8	173.3	-77.1	32.7	0	0	0	110.9	Y175 V176 T180 V182	Y175-W178 AromaticContact CD1-CD1 3.17Å; Y175-W178 HydrophobicContact CD1-CG 4Å; Y175-W178 AromaticContact CD1-NE1 3.63Å; Y175-W178 AromaticContact CE1-CD1 3.57Å; Y175-W178 AromaticContact CE1-NE1 3.85Å; Y175-W178 PolarHBondContact O-N 3.36Å; V176-W178 PolarHBondContact O-N 3.38Å; W178-T180 VanDerWaalsContact C-N 3.34Å; W178-T180 PolarHBondContact O-N 3.31Å; W178-V182 VanDerWaalsContact O-CG2 3.29Å; W178-V182 WeakPolarHBondContact O-CG2 3.36Å; W178-V182 PolarHBondContact O-N 2.9Å
179	G	55.2	Low	72.1	Confident	4 Å²	4	72.7 Å²	72.7	4%	0.041	34%	0.341	C	S	.	.	H	α-helix	trans	-61.7	-39.7	178.4	0	0	0	0	0	113.1	V176 Q183 N324	V176-G179 PolarHBondContact O-N 3.42Å; G179-Q183 WeakPolarHBondContact O-CB 3.13Å; G179-Q183 PolarHBondContact O-N 3.34Å; G179-N324 PolarHBondContact O-ND2 2.57Å
180	T	57	Low	71.3	Confident	65 Å²	65	72.6 Å²	72.6	40%	0.399	34%	0.34	S	S	.	.	H	α-helix	trans	-71.7	-41.1	-177.2	53.2	0	0	0	0	113.6	K177 W178 V182 Q183 D184	K177-T180 PolarHBondContact O-OG1 2.86Å; W178-T180 VanDerWaalsContact C-N 3.34Å; W178-T180 PolarHBondContact O-N 3.31Å; T180-V182 PolarHBondContact O-N 3.47Å; T180-Q183 PolarHBondContact O-N 3.4Å; T180-D184 PolarHBondContact O-N 3.49Å
181	R	62.2	Low	70.8	Confident	187 Å²	187	67.8 Å²	67.8	71%	0.706	32%	0.322	S	S	*	.	H	α-helix	trans	-68.4	-34.8	178.2	-72.4	-173.2	-174.9	141.4	-1.1	113.3	Q183	R181-Q183 VanDerWaalsContact C-N 3.33Å
182	V	62.1	Low	70.5	Confident	63 Å²	63	71.1 Å²	71.1	38%	0.382	34%	0.337	S	S	.	.	H	α-helix	trans	-70.3	-33.7	179.1	170.3	0	0	0	0	110.8	W178 T180 F186	W178-V182 VanDerWaalsContact O-CG2 3.29Å; W178-V182 WeakPolarHBondContact O-CG2 3.36Å; W178-V182 PolarHBondContact O-N 2.9Å; T180-V182 PolarHBondContact O-N 3.47Å; V182-F186 HydrophobicContact CG1-CD2 3.8Å; V182-F186 HydrophobicContact CG1-CE2 3.12Å; V182-F186 HydrophobicContact CG1-CZ 3.7Å; V182-F186 WeakPolarHBondContact O-CD2 3.34Å; V182-F186 WeakPolarHBondContact O-CG 2.99Å; V182-F186 PolarHBondContact O-N 3.29Å
183	Q	61.6	Low	70.3	Confident	40 Å²	40	71.7 Å²	71.7	19%	0.187	34%	0.341	C	S	.	.	H	α-helix	trans	-65.3	-40.6	178	-179	178.8	-19.8	0	0	113.6	G179 T180 R181 F185 F186 T187	G179-Q183 WeakPolarHBondContact O-CB 3.13Å; G179-Q183 PolarHBondContact O-N 3.34Å; T180-Q183 PolarHBondContact O-N 3.4Å; R181-Q183 VanDerWaalsContact C-N 3.33Å; Q183-F185 PolarHBondContact O-N 3.19Å; Q183-F186 PolarHBondContact O-N 2.98Å; Q183-T187 PolarHBondContact O-N 2.83Å; Q183-T187 PolarHBondContact O-OG1 3.28Å
184	D	64.2	Low	70.4	Confident	102 Å²	102	71.2 Å²	71.2	55%	0.545	34%	0.338	S	S	.	.	H	α-helix	trans	-62	-45.1	-178.4	-71.3	-18.7	0	0	0	111.4	T180 F186 T187 Y188	T180-D184 PolarHBondContact O-N 3.49Å; D184-F186 PolarHBondContact O-N 2.81Å; D184-T187 WeakPolarHBondContact O-CB 3.47Å; D184-T187 PolarHBondContact O-N 3.29Å; D184-Y188 WeakPolarHBondContact O-CD2 3.43Å; D184-Y188 PolarHBondContact O-N 2.9Å
185	F	69.8	Low	70.6	Confident	141 Å²	141	73.6 Å²	73.6	62%	0.618	35%	0.346	S	S	*	.	H	α-helix	trans	-59.9	-44.9	177.2	176.5	-102.1	0	0	0	112.3	Q183 T187 Y188 A189	Q183-F185 PolarHBondContact O-N 3.19Å; F185-T187 PolarHBondContact O-N 3.07Å; F185-Y188 PolarHBondContact O-N 3.47Å; F185-A189 PolarHBondContact O-N 3.48Å
186	F	70.6	Confident	71.2	Confident	26 Å²	26	70 Å²	70	11%	0.114	34%	0.339	C	S	.	.	H	α-helix	trans	-68.1	-24.4	179.3	-62.8	-33.8	0	0	0	113.5	V182 Q183 D184 A189 K190 L317 F320	V182-F186 HydrophobicContact CG1-CD2 3.8Å; V182-F186 HydrophobicContact CG1-CE2 3.12Å; V182-F186 HydrophobicContact CG1-CZ 3.7Å; V182-F186 WeakPolarHBondContact O-CD2 3.34Å; V182-F186 WeakPolarHBondContact O-CG 2.99Å; V182-F186 PolarHBondContact O-N 3.29Å; Q183-F186 PolarHBondContact O-N 2.98Å; D184-F186 PolarHBondContact O-N 2.81Å; F186-A189 PolarHBondContact O-N 3.25Å; F186-K190 WeakPolarHBondContact O-CG 3.17Å; F186-K190 PolarHBondContact O-N 3.27Å; F186-K190 VanDerWaalsContact O-N 3.12Å; F186-L317 HydrophobicContact CD1-CB 3.76Å; F186-L317 HydrophobicContact CD1-CD1 4.16Å; F186-L317 HydrophobicContact CD1-CD2 4.31Å; F186-L317 HydrophobicContact CD1-CG 4.28Å; F186-L317 HydrophobicContact CE1-CB 3.96Å; F186-L317 HydrophobicContact CE1-CD1 3.87Å; F186-L317 HydrophobicContact CE1-CD2 3.61Å; F186-L317 HydrophobicContact CE1-CG 4Å; F186-L317 HydrophobicContact CE2-CD2 4.44Å; F186-L317 HydrophobicContact CG-CB 4.2Å; F186-L317 HydrophobicContact CZ-CD2 3.69Å; F186-F320 AromaticContact CE2-CD1 3.93Å; F186-F320 HydrophobicContact CE2-CD1 3.93Å
187	T	69.8	Low	72.5	Confident	23 Å²	23	67.8 Å²	67.8	14%	0.141	33%	0.325	C	S	.	.	H	α-helix	trans	-67.9	-40.7	177.1	-58.7	0	0	0	0	112.1	Q183 D184 F185 K190 V191	Q183-T187 PolarHBondContact O-N 2.83Å; Q183-T187 PolarHBondContact O-OG1 3.28Å; D184-T187 WeakPolarHBondContact O-CB 3.47Å; D184-T187 PolarHBondContact O-N 3.29Å; F185-T187 PolarHBondContact O-N 3.07Å; T187-K190 VanDerWaalsContact O-CG 3.3Å; T187-K190 WeakPolarHBondContact O-CG 3.32Å; T187-V191 WeakPolarHBondContact O-CG2 3.31Å
188	Y	74.3	Confident	73.8	Confident	150 Å²	150	62.3 Å²	62.3	59%	0.588	30%	0.302	S	S	*	.	H	α-helix	trans	-69.4	-42.9	174.3	-64.8	-72.5	0	0	0	111.8	D184 F185 K190 V191 I192	D184-Y188 WeakPolarHBondContact O-CD2 3.43Å; D184-Y188 PolarHBondContact O-N 2.9Å; F185-Y188 PolarHBondContact O-N 3.47Å; Y188-K190 VanDerWaalsContact C-N 3.35Å; Y188-K190 PolarHBondContact O-N 3.34Å; Y188-V191 PolarHBondContact O-N 2.96Å; Y188-I192 WeakPolarHBondContact O-CG1 3.31Å; Y188-I192 PolarHBondContact O-N 2.94Å; Y188-I192 VanDerWaalsContact O-N 3.11Å
189	A	74.6	Confident	75.4	Confident	27 Å²	27	58.5 Å²	58.5	22%	0.223	29%	0.294	C	S	.	.	H	α-helix	trans	-59	-42.7	-178.1	0	0	0	0	0	112.8	F185 F186 I192 A193	F185-A189 PolarHBondContact O-N 3.48Å; F186-A189 PolarHBondContact O-N 3.25Å; A189-I192 PolarHBondContact O-N 2.97Å; A189-A193 PolarHBondContact O-N 2.96Å
190	K	76.3	Confident	77.1	Confident	9 Å²	9	59.5 Å²	59.5	4%	0.039	30%	0.299	C	S	.	.	H	α-helix	trans	-70.8	-35	179.8	70.6	-175.9	176.9	-171.7	0	113.7	G47 I50 F186 T187 Y188 I192 A193 L194 S318	G47-K190 WeakPolarHBondContact O-CE 3.24Å; G47-K190 PolarHBondContact O-NZ 3.48Å; I50-K190 VanDerWaalsContact O-CD 3.24Å; I50-K190 WeakPolarHBondContact O-CD 3.45Å; I50-K190 WeakPolarHBondContact O-CE 3.35Å; I50-K190 PolarHBondContact O-NZ 3.17Å; F186-K190 WeakPolarHBondContact O-CG 3.17Å; F186-K190 PolarHBondContact O-N 3.27Å; F186-K190 VanDerWaalsContact O-N 3.12Å; T187-K190 VanDerWaalsContact O-CG 3.3Å; T187-K190 WeakPolarHBondContact O-CG 3.32Å; Y188-K190 VanDerWaalsContact C-N 3.35Å; Y188-K190 PolarHBondContact O-N 3.34Å; K190-I192 VanDerWaalsContact C-N 3.32Å; K190-A193 PolarHBondContact O-N 3.37Å; K190-L194 PolarHBondContact O-N 3.25Å; K190-S318 WeakPolarHBondContact CD-OG 3.34Å
191	V	79.4	Confident	78.7	Confident	37 Å²	37	56.4 Å²	56.4	22%	0.224	28%	0.281	C	S	.	.	H	α-helix	trans	-65.7	-41.1	176.6	173.4	0	0	0	0	109.6	T187 Y188 A193 L194 I195	T187-V191 WeakPolarHBondContact O-CG2 3.31Å; Y188-V191 PolarHBondContact O-N 2.96Å; V191-A193 VanDerWaalsContact C-N 3.35Å; V191-A193 PolarHBondContact O-N 2.89Å; V191-L194 PolarHBondContact O-N 3.31Å; V191-I195 HydrophobicContact CG1-CD1 3.83Å; V191-I195 HydrophobicContact CG1-CG1 4.44Å; V191-I195 VanDerWaalsContact O-CG1 3.26Å; V191-I195 WeakPolarHBondContact O-CG1 3.21Å; V191-I195 PolarHBondContact O-N 3.07Å
192	I	82.9	Confident	80.2	Confident	113 Å²	113	51.9 Å²	51.9	58%	0.579	27%	0.27	S	S	*	.	H	α-helix	trans	-61	-43.8	174	-66.2	166.4	0	0	0	111	Y188 A189 K190 L194 I195 A196	Y188-I192 WeakPolarHBondContact O-CG1 3.31Å; Y188-I192 PolarHBondContact O-N 2.94Å; Y188-I192 VanDerWaalsContact O-N 3.11Å; A189-I192 PolarHBondContact O-N 2.97Å; K190-I192 VanDerWaalsContact C-N 3.32Å; I192-L194 PolarHBondContact O-N 3.31Å; I192-I195 PolarHBondContact O-N 3.25Å; I192-A196 PolarHBondContact O-N 3.48Å
193	A	82.6	Confident	81.7	Confident	13 Å²	13	52.6 Å²	52.6	11%	0.107	27%	0.274	C	S	.	.	H	α-helix	trans	-60.9	-42.3	177.9	0	0	0	0	0	112.5	A189 K190 V191 A196 V197 A314	A189-A193 PolarHBondContact O-N 2.96Å; K190-A193 PolarHBondContact O-N 3.37Å; V191-A193 VanDerWaalsContact C-N 3.35Å; V191-A193 PolarHBondContact O-N 2.89Å; A193-A196 WeakPolarHBondContact O-CB 3.5Å; A193-A196 PolarHBondContact O-N 3.26Å; A193-V197 WeakPolarHBondContact O-CG2 3.32Å; A193-V197 PolarHBondContact O-N 3.37Å; A193-V197 VanDerWaalsContact O-N 3.09Å; A193-A314 HydrophobicContact CB-CB 3.74Å
194	L	86.8	Confident	83.2	Confident	2 Å²	2	52.7 Å²	52.7	1%	0.01	27%	0.274	C	S	.	.	H	α-helix	trans	-67.7	-40.3	175.6	-73.7	173	0	0	0	112.5	I50 I54 F55 K190 V191 I192 A196 V197 I198 I272 T276	I50-L194 HydrophobicContact CG2-CD1 3.21Å; I54-L194 HydrophobicContact CG2-CD1 4.35Å; I54-L194 HydrophobicContact CG2-CD2 4.26Å; F55-L194 HydrophobicContact CE1-CD2 3.84Å; F55-L194 HydrophobicContact CZ-CD2 3.76Å; F55-L194 HydrophobicContact CZ-CG 4.14Å; K190-L194 PolarHBondContact O-N 3.25Å; V191-L194 PolarHBondContact O-N 3.31Å; I192-L194 PolarHBondContact O-N 3.31Å; L194-A196 VanDerWaalsContact C-N 3.26Å; L194-A196 PolarHBondContact O-N 2.8Å; L194-V197 PolarHBondContact O-N 2.85Å; L194-I198 VanDerWaalsContact O-CG1 3.3Å; L194-I198 WeakPolarHBondContact O-CG1 3.49Å; L194-I198 PolarHBondContact O-N 3.3Å; L194-I272 HydrophobicContact CB-CG2 4.43Å; L194-I272 HydrophobicContact CD1-CG2 4.09Å; L194-T276 HydrophobicContact CD2-CG2 3.95Å
195	I	88.7	Confident	84.6	Confident	79 Å²	79	50.5 Å²	50.5	41%	0.405	26%	0.261	S	S	.	.	H	α-helix	trans	-59.8	-41.2	174.5	-70.5	167.8	0	0	0	110.2	V191 I192 I198 I199	V191-I195 HydrophobicContact CG1-CD1 3.83Å; V191-I195 HydrophobicContact CG1-CG1 4.44Å; V191-I195 VanDerWaalsContact O-CG1 3.26Å; V191-I195 WeakPolarHBondContact O-CG1 3.21Å; V191-I195 PolarHBondContact O-N 3.07Å; I192-I195 PolarHBondContact O-N 3.25Å; I195-I198 PolarHBondContact O-N 2.97Å; I195-I199 HydrophobicContact CG2-CD1 3.58Å; I195-I199 HydrophobicContact CG2-CG1 4.18Å; I195-I199 WeakPolarHBondContact O-CB 3.37Å; I195-I199 VanDerWaalsContact O-CG1 3.29Å; I195-I199 WeakPolarHBondContact O-CG1 3.42Å; I195-I199 PolarHBondContact O-N 3.37Å
196	A	88	Confident	85.6	Confident	33 Å²	33	47 Å²	47	27%	0.273	27%	0.266	S	S	.	.	H	α-helix	trans	-61.4	-44.4	175.7	0	0	0	0	0	112	I192 A193 L194 I198 T200 F304	I192-A196 PolarHBondContact O-N 3.48Å; A193-A196 WeakPolarHBondContact O-CB 3.5Å; A193-A196 PolarHBondContact O-N 3.26Å; L194-A196 VanDerWaalsContact C-N 3.26Å; L194-A196 PolarHBondContact O-N 2.8Å; A196-I198 PolarHBondContact O-N 3.4Å; A196-T200 VanDerWaalsContact O-CB 3.28Å; A196-T200 WeakPolarHBondContact O-CB 3.26Å; A196-T200 PolarHBondContact O-N 3.48Å; A196-T200 PolarHBondContact O-OG1 3.46Å; A196-F304 HydrophobicContact CB-CZ 4.28Å
197	V	89.8	Confident	86.6	Confident	2 Å²	2	51.2 Å²	51.2	1%	0.012	29%	0.286	C	S	.	.	H	α-helix	trans	-58.8	-46.2	174.3	170.2	0	0	0	0	111.2	A193 L194 T200 G201 T276 A279 Y280 F299 I311	A193-V197 WeakPolarHBondContact O-CG2 3.32Å; A193-V197 PolarHBondContact O-N 3.37Å; A193-V197 VanDerWaalsContact O-N 3.09Å; L194-V197 PolarHBondContact O-N 2.85Å; V197-T200 PolarHBondContact O-N 3.47Å; V197-G201 PolarHBondContact O-N 2.97Å; V197-T276 HydrophobicContact CG1-CG2 4.24Å; V197-A279 HydrophobicContact CG1-CB 3.97Å; V197-A279 WeakPolarHBondContact O-CB 3.5Å; V197-Y280 HydrophobicContact CG1-CD1 4.28Å; V197-Y280 HydrophobicContact CG1-CE1 3.78Å; V197-F299 HydrophobicContact CB-CE1 4.26Å; V197-F299 HydrophobicContact CG1-CD1 4.24Å; V197-F299 HydrophobicContact CG1-CE1 3.88Å; V197-F299 HydrophobicContact CG1-CZ 4.17Å; V197-F299 HydrophobicContact CG2-CD1 4.27Å; V197-F299 HydrophobicContact CG2-CE1 4.16Å; V197-I311 HydrophobicContact CG2-CD1 4.3Å
198	I	93.2	Very high	87.6	Confident	16 Å²	16	52.3 Å²	52.3	8%	0.082	30%	0.301	C	S	.	.	H	α-helix	trans	-63.1	-50.5	-179.9	-68.5	166.6	0	0	0	111.2	L194 I195 A196 T200 G201 L202 I272 L275	L194-I198 VanDerWaalsContact O-CG1 3.3Å; L194-I198 WeakPolarHBondContact O-CG1 3.49Å; L194-I198 PolarHBondContact O-N 3.3Å; I195-I198 PolarHBondContact O-N 2.97Å; A196-I198 PolarHBondContact O-N 3.4Å; I198-T200 VanDerWaalsContact C-N 3.31Å; I198-T200 PolarHBondContact O-N 3.47Å; I198-G201 PolarHBondContact O-N 3.37Å; I198-L202 HydrophobicContact CG2-CD1 4.08Å; I198-L202 HydrophobicContact CG2-CG 4.43Å; I198-L202 WeakPolarHBondContact O-CG 3.35Å; I198-L202 PolarHBondContact O-N 2.9Å; I198-I272 HydrophobicContact CD1-CG2 4.16Å; I198-L275 HydrophobicContact CD1-CB 3.96Å; I198-L275 HydrophobicContact CG1-CB 3.9Å; I198-L275 HydrophobicContact CG2-CB 3.93Å; I198-L275 HydrophobicContact CG2-CD1 4.05Å
199	I	93.4	Very high	88.3	Confident	96 Å²	96	50.9 Å²	50.9	49%	0.492	30%	0.296	S	S	.	.	H	α-helix	trans	-58.9	-46.4	179.8	-69.4	170.5	0	0	0	110	I195 G201 L202 V203	I195-I199 HydrophobicContact CG2-CD1 3.58Å; I195-I199 HydrophobicContact CG2-CG1 4.18Å; I195-I199 WeakPolarHBondContact O-CB 3.37Å; I195-I199 VanDerWaalsContact O-CG1 3.29Å; I195-I199 WeakPolarHBondContact O-CG1 3.42Å; I195-I199 PolarHBondContact O-N 3.37Å; I199-G201 VanDerWaalsContact C-N 3.33Å; I199-G201 PolarHBondContact O-N 2.89Å; I199-L202 PolarHBondContact O-N 2.94Å; I199-V203 HydrophobicContact CG2-CG2 4.43Å; I199-V203 WeakPolarHBondContact O-CG2 2.99Å; I199-V203 PolarHBondContact O-N 3.4Å
200	T	91.1	Very high	89	Confident	25 Å²	25	52.5 Å²	52.5	15%	0.153	30%	0.303	C	S	.	.	H	α-helix	trans	-60.9	-42.1	178.1	-67.7	0	0	0	0	111.9	A196 V197 I198 V203 K204 F299 V303 F304	A196-T200 VanDerWaalsContact O-CB 3.28Å; A196-T200 WeakPolarHBondContact O-CB 3.26Å; A196-T200 PolarHBondContact O-N 3.48Å; A196-T200 PolarHBondContact O-OG1 3.46Å; V197-T200 PolarHBondContact O-N 3.47Å; I198-T200 VanDerWaalsContact C-N 3.31Å; I198-T200 PolarHBondContact O-N 3.47Å; T200-V203 PolarHBondContact O-N 2.93Å; T200-K204 WeakPolarHBondContact O-CG 3.44Å; T200-K204 PolarHBondContact O-N 3.14Å; T200-F299 HydrophobicContact CG2-CE1 4.19Å; T200-F299 HydrophobicContact CG2-CZ 3.94Å; T200-V303 HydrophobicContact CG2-CB 3.92Å; T200-V303 HydrophobicContact CG2-CG1 3.16Å; T200-V303 HydrophobicContact CG2-CG2 4.33Å; T200-F304 HydrophobicContact CG2-CE2 4.5Å; T200-F304 HydrophobicContact CG2-CZ 4.31Å; T200-F304 VanDerWaalsContact OG1-CZ 3.26Å; T200-F304 WeakPolarHBondContact OG1-CZ 3.25Å
201	G	92.1	Very high	89.5	Confident	1 Å²	1	59.2 Å²	59.2	1%	0.01	34%	0.335	C	S	.	.	H	α-helix	trans	-60.1	-47.3	173.8	0	0	0	0	0	112.9	V197 I198 I199 V203 K204 I205	V197-G201 PolarHBondContact O-N 2.97Å; I198-G201 PolarHBondContact O-N 3.37Å; I199-G201 VanDerWaalsContact C-N 3.33Å; I199-G201 PolarHBondContact O-N 2.89Å; G201-V203 VanDerWaalsContact C-N 3.35Å; G201-V203 PolarHBondContact O-N 3.14Å; G201-K204 WeakPolarHBondContact O-CB 3.48Å; G201-K204 PolarHBondContact O-N 3.48Å; G201-K204 VanDerWaalsContact O-N 3.17Å; G201-I205 WeakPolarHBondContact O-CG1 3.36Å; G201-I205 PolarHBondContact O-N 2.91Å
202	L	93.4	Very high	89.8	Confident	92 Å²	92	59.7 Å²	59.7	48%	0.482	34%	0.336	S	S	.	.	H	α-helix	trans	-62.5	-39.6	177.8	-68.3	175.6	0	0	0	112.5	I198 I199 I205 G206	I198-L202 HydrophobicContact CG2-CD1 4.08Å; I198-L202 HydrophobicContact CG2-CG 4.43Å; I198-L202 WeakPolarHBondContact O-CG 3.35Å; I198-L202 PolarHBondContact O-N 2.9Å; I199-L202 PolarHBondContact O-N 2.94Å; L202-I205 PolarHBondContact O-N 3.46Å; L202-G206 PolarHBondContact O-N 3.08Å
203	V	93.7	Very high	90	Very high	77 Å²	77	56.4 Å²	56.4	47%	0.467	32%	0.317	S	S	.	.	H	α-helix	trans	-63.2	-42.1	174.4	170.7	0	0	0	0	110.9	I199 T200 G201 G206 Q207	I199-V203 HydrophobicContact CG2-CG2 4.43Å; I199-V203 WeakPolarHBondContact O-CG2 2.99Å; I199-V203 PolarHBondContact O-N 3.4Å; T200-V203 PolarHBondContact O-N 2.93Å; G201-V203 VanDerWaalsContact C-N 3.35Å; G201-V203 PolarHBondContact O-N 3.14Å; V203-G206 CarbonylContact O-C 3.55Å; V203-G206 PolarHBondContact O-N 3.4Å; V203-G206 VanDerWaalsContact O-N 3.17Å; V203-Q207 WeakPolarHBondContact O-CG 3.33Å; V203-Q207 PolarHBondContact O-N 3.43Å
204	K	92.4	Very high	90.3	Very high	43 Å²	43	61.8 Å²	61.8	19%	0.187	34%	0.344	C	S	.	.	H	α-helix	trans	-64.1	-39.7	176.7	-74.9	-73.5	-178.6	-177.8	0	112.5	T200 G201 G206 Q207 G208 Y209 T282 V283	T200-K204 WeakPolarHBondContact O-CG 3.44Å; T200-K204 PolarHBondContact O-N 3.14Å; G201-K204 WeakPolarHBondContact O-CB 3.48Å; G201-K204 PolarHBondContact O-N 3.48Å; G201-K204 VanDerWaalsContact O-N 3.17Å; K204-G206 VanDerWaalsContact C-N 3.34Å; K204-Q207 WeakPolarHBondContact O-CB 3.29Å; K204-Q207 PolarHBondContact O-N 3.39Å; K204-Q207 VanDerWaalsContact O-N 3.17Å; K204-G208 PolarHBondContact O-N 3.02Å; K204-Y209 HydrophobicContact CD-CD2 3.95Å; K204-Y209 HydrophobicContact CD-CE2 4.15Å; K204-Y209 HydrophobicContact CD-CG 4.38Å; K204-Y209 WeakPolarHBondContact O-CB 3.22Å; K204-Y209 WeakPolarHBondContact O-CD2 3.42Å; K204-Y209 PolarHBondContact O-N 2.83Å; K204-Y209 VanDerWaalsContact O-N 3.14Å; K204-T282 HydrophobicContact CB-CG2 3.75Å; K204-V283 HydrophobicContact CB-CG2 4.39Å; K204-V283 HydrophobicContact CG-CG2 4.09Å
205	I	92.9	Very high	90.2	Very high	55 Å²	55	63.6 Å²	63.6	28%	0.282	36%	0.364	S	S	.	.	H	α-helix	trans	-59.7	-46.7	170.7	-67	173.1	0	0	0	110.1	G201 L202 Q207 G208 T210 V278 T282	G201-I205 WeakPolarHBondContact O-CG1 3.36Å; G201-I205 PolarHBondContact O-N 2.91Å; L202-I205 PolarHBondContact O-N 3.46Å; I205-Q207 PolarHBondContact O-N 3.37Å; I205-G208 PolarHBondContact O-N 3.09Å; I205-T210 HydrophobicContact CG2-CG2 4.12Å; I205-V278 HydrophobicContact CD1-CG1 3.79Å; I205-T282 HydrophobicContact CG1-CG2 3.57Å; I205-T282 WeakPolarHBondContact CG1-OG1 3.44Å
206	G	91.6	Very high	90.3	Very high	69 Å²	69	62.6 Å²	62.6	71%	0.711	36%	0.358	S	S	*	.	H	α-helix	trans	-61.8	-23.7	176.8	0	0	0	0	0	114.4	L202 V203 K204 G208	L202-G206 PolarHBondContact O-N 3.08Å; V203-G206 CarbonylContact O-C 3.55Å; V203-G206 PolarHBondContact O-N 3.4Å; V203-G206 VanDerWaalsContact O-N 3.17Å; K204-G206 VanDerWaalsContact C-N 3.34Å; G206-G208 VanDerWaalsContact C-N 3.31Å
207	Q	91.9	Very high	90.6	Very high	114 Å²	114	66.4 Å²	66.4	53%	0.533	37%	0.369	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.1	-2.9	173.1	-71.1	173.6	-2.8	0	0	113.5	V203 K204 I205 Y209	V203-Q207 WeakPolarHBondContact O-CG 3.33Å; V203-Q207 PolarHBondContact O-N 3.43Å; K204-Q207 WeakPolarHBondContact O-CB 3.29Å; K204-Q207 PolarHBondContact O-N 3.39Å; K204-Q207 VanDerWaalsContact O-N 3.17Å; I205-Q207 PolarHBondContact O-N 3.37Å; Q207-Y209 HydrophobicContact CB-CD2 3.85Å; Q207-Y209 HydrophobicContact CB-CE2 4Å
208	G	89.8	Confident	90.6	Very high	45 Å²	45	72.2 Å²	72.2	46%	0.464	40%	0.4	S	S	.	.	T	Hydrogen-bonded Turn	trans	92.3	12.5	178.4	0	0	0	0	0	115.5	K204 I205 G206 T210	K204-G208 PolarHBondContact O-N 3.02Å; I205-G208 PolarHBondContact O-N 3.09Å; G206-G208 VanDerWaalsContact C-N 3.31Å; G208-T210 PolarHBondContact O-N 3.14Å
209	Y	89.4	Confident	90.4	Very high	121 Å²	121	74.6 Å²	74.6	48%	0.475	43%	0.428	S	S	.	.			trans	-77.7	65	175.1	-70.7	-96.7	0	0	0	111.4	K204 Q207 T282	K204-Y209 HydrophobicContact CD-CD2 3.95Å; K204-Y209 HydrophobicContact CD-CE2 4.15Å; K204-Y209 HydrophobicContact CD-CG 4.38Å; K204-Y209 WeakPolarHBondContact O-CB 3.22Å; K204-Y209 WeakPolarHBondContact O-CD2 3.42Å; K204-Y209 PolarHBondContact O-N 2.83Å; K204-Y209 VanDerWaalsContact O-N 3.14Å; Q207-Y209 HydrophobicContact CB-CD2 3.85Å; Q207-Y209 HydrophobicContact CB-CE2 4Å; Y209-T282 VanDerWaalsContact O-CG2 3.26Å; Y209-T282 WeakPolarHBondContact O-CG2 3.19Å
210	T	88.8	Confident	90.3	Very high	61 Å²	61	71 Å²	71	37%	0.374	41%	0.411	S	S	.	.			trans	-110.9	1.9	-178	57.4	0	0	0	0	114.2	I205 G208 N212 F213	I205-T210 HydrophobicContact CG2-CG2 4.12Å; G208-T210 PolarHBondContact O-N 3.14Å; T210-N212 PolarHBondContact O-N 2.96Å; T210-N212 VanDerWaalsContact O-N 3.17Å; T210-F213 WeakPolarHBondContact O-CB 3.25Å; T210-F213 PolarHBondContact O-N 2.67Å
211	Q	88.1	Confident	90.4	Very high	150 Å²	150	70.5 Å²	70.5	70%	0.701	41%	0.409	S	S	*	.	G	3₁₀ helix	trans	-57	-34.6	-174.9	-64.8	166	5.1	0	0	112.9	F213 D214	Q211-F213 PolarHBondContact O-N 2.83Å; Q211-D214 WeakPolarHBondContact O-CB 3.29Å; Q211-D214 PolarHBondContact O-N 2.92Å; Q211-D214 VanDerWaalsContact O-N 3.13Å
212	N	85.9	Confident	90.3	Very high	47 Å²	47	78.1 Å²	78.1	25%	0.251	44%	0.444	S	S	.	.	G	3₁₀ helix	trans	-66.1	-16.9	176.9	-71	-15	0	0	0	113.3	Y68 T210 Y281 L284	Y68-N212 WeakPolarHBondContact CD2-O 3.41Å; Y68-N212 HydrophobicContact CE2-CB 3.92Å; Y68-N212 VanDerWaalsContact CE2-O 3.24Å; Y68-N212 WeakPolarHBondContact CE2-O 3.49Å; T210-N212 PolarHBondContact O-N 2.96Å; T210-N212 VanDerWaalsContact O-N 3.17Å; N212-Y281 WeakPolarHBondContact CB-O 3.31Å; N212-Y281 PolarHBondContact ND2-O 3.35Å; N212-L284 PolarHBondContact ND2-O 2.76Å
213	F	87.4	Confident	90.2	Very high	44 Å²	44	77 Å²	77	19%	0.193	44%	0.438	C	S	.	.	G	3₁₀ helix	trans	-92.9	-7.1	176.6	-60.6	-71.8	0	0	0	113.1	T210 Q211 G215 M216 V278 T282	T210-F213 WeakPolarHBondContact O-CB 3.25Å; T210-F213 PolarHBondContact O-N 2.67Å; Q211-F213 PolarHBondContact O-N 2.83Å; F213-G215 PolarHBondContact O-N 2.6Å; F213-M216 WeakPolarHBondContact O-CB 3.22Å; F213-M216 PolarHBondContact O-N 3.13Å; F213-V278 HydrophobicContact CZ-CG1 4.12Å; F213-T282 WeakPolarHBondContact CE2-OG1 3.36Å
214	D	87.6	Confident	90	Very high	125 Å²	125	76.2 Å²	76.2	67%	0.668	44%	0.435	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.2	123.7	171.9	-63.8	-30.2	0	0	0	108.5	Q211 M216	Q211-D214 WeakPolarHBondContact O-CB 3.29Å; Q211-D214 PolarHBondContact O-N 2.92Å; Q211-D214 VanDerWaalsContact O-N 3.13Å; D214-M216 PolarHBondContact O-N 3.47Å
215	G	86.1	Confident	89.9	Confident	41 Å²	41	74.1 Å²	74.1	42%	0.423	43%	0.426	S	S	.	.	T	Hydrogen-bonded Turn	trans	66.8	33	-174.9	0	0	0	0	0	113.6	F213 F217 D218	F213-G215 PolarHBondContact O-N 2.6Å; G215-F217 PolarHBondContact O-N 3.21Å; G215-D218 WeakPolarHBondContact CA-OD2 3.14Å; G215-D218 VanDerWaalsContact O-CB 3.27Å; G215-D218 WeakPolarHBondContact O-CB 3.36Å; G215-D218 VanDerWaalsContact O-CG 3.29Å; G215-D218 PolarHBondContact O-N 3.31Å
216	M	90.6	Very high	89.8	Confident	58 Å²	58	75.5 Å²	75.5	29%	0.286	43%	0.431	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.4	-18.4	-173.8	67	-174.2	-71.8	0	0	116	S67 Y68 G69 L72 F213 D214	S67-M216 WeakPolarHBondContact CB-O 3.34Å; Y68-M216 PolarHBondContact N-O 3.34Å; G69-M216 VanDerWaalsContact CA-CE 3.44Å; G69-M216 WeakPolarHBondContact CA-O 3.46Å; G69-M216 PolarHBondContact N-O 2.84Å; L72-M216 HydrophobicContact CD1-CE 4.28Å; F213-M216 WeakPolarHBondContact O-CB 3.22Å; F213-M216 PolarHBondContact O-N 3.13Å; D214-M216 PolarHBondContact O-N 3.47Å
217	F	93.4	Very high	89.9	Confident	113 Å²	113	74.5 Å²	74.5	50%	0.496	41%	0.409	S	S	.	.	T	Hydrogen-bonded Turn	trans	-101.9	-0.3	177.4	-67.6	-79.4	0	0	0	113.8	G69 V73 G215 G219 S220	G69-F217 VanDerWaalsContact C-CE1 3.4Å; V73-F217 HydrophobicContact CG2-CE1 4.33Å; G215-F217 PolarHBondContact O-N 3.21Å; F217-G219 PolarHBondContact O-N 3.23Å; F217-S220 WeakPolarHBondContact O-CB 3.17Å; F217-S220 PolarHBondContact O-N 3.19Å; F217-S220 PolarHBondContact O-OG 3.19Å
218	D	90.2	Very high	89.8	Confident	124 Å²	124	69.1 Å²	69.1	66%	0.663	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.3	135.8	-179.1	-66.3	-12.9	0	0	0	110.1	S67 G215 S220	S67-D218 WeakPolarHBondContact CB-O 3.45Å; G215-D218 WeakPolarHBondContact CA-OD2 3.14Å; G215-D218 VanDerWaalsContact O-CB 3.27Å; G215-D218 WeakPolarHBondContact O-CB 3.36Å; G215-D218 VanDerWaalsContact O-CG 3.29Å; G215-D218 PolarHBondContact O-N 3.31Å; D218-S220 PolarHBondContact O-N 3.05Å
219	G	87.7	Confident	89.9	Confident	65 Å²	65	67.6 Å²	67.6	67%	0.67	37%	0.365	S	S	*	.	T	Hydrogen-bonded Turn	trans	73.2	8	-177.4	0	0	0	0	0	115.4	A66 F217 S221	A66-G219 VanDerWaalsContact CB-O 3.31Å; A66-G219 WeakPolarHBondContact CB-O 3.24Å; F217-G219 PolarHBondContact O-N 3.23Å; G219-S221 PolarHBondContact O-N 3.37Å
220	S	93.3	Very high	90.2	Very high	20 Å²	20	61.9 Å²	61.9	14%	0.14	34%	0.343	C	S	.	.			trans	-54.1	127.4	179.4	-64.9	0	0	0	0	112.5	S67 F217 D218 Q222	S67-S220 WeakPolarHBondContact CB-OG 3.31Å; S67-S220 PolarHBondContact OG-OG 3.01Å; F217-S220 WeakPolarHBondContact O-CB 3.17Å; F217-S220 PolarHBondContact O-N 3.19Å; F217-S220 PolarHBondContact O-OG 3.19Å; D218-S220 PolarHBondContact O-N 3.05Å; S220-Q222 PolarHBondContact O-N 3.38Å; S220-Q222 PolarHBondContact O-NE2 2.8Å; S220-Q222 VanDerWaalsContact O-NE2 3.09Å
221	S	91.5	Very high	90.4	Very high	16 Å²	16	59.8 Å²	59.8	11%	0.112	33%	0.329	C	S	.	.			trans	-60.1	132.5	175.5	-173.6	0	0	0	0	111.2	H64 S65 L70 G219 D223 H226	H64-S221 WeakPolarHBondContact O-CB 3.33Å; S65-S221 PolarHBondContact O-N 3.16Å; L70-S221 WeakPolarHBondContact CD2-O 3.23Å; G219-S221 PolarHBondContact O-N 3.37Å; S221-D223 PolarHBondContact OG-N 2.93Å; S221-H226 WeakPolarHBondContact OG-CB 3.35Å; S221-H226 PolarHBondContact OG-ND1 3.1Å
222	Q	91.3	Very high	90.7	Very high	160 Å²	160	52.8 Å²	52.8	75%	0.748	30%	0.296	S	S	*	.			trans	-103	-4.5	174.9	-57.1	-57.3	-50.2	0	0	112.3	S220 P224	S220-Q222 PolarHBondContact O-N 3.38Å; S220-Q222 PolarHBondContact O-NE2 2.8Å; S220-Q222 VanDerWaalsContact O-NE2 3.09Å; Q222-P224 WeakPolarHBondContact O-CD 3.36Å
223	D	91.3	Very high	91.1	Very high	68 Å²	68	50.5 Å²	50.5	36%	0.364	28%	0.284	S	S	.	.			trans	-75.8	121.4	-179.4	176.4	49.3	0	0	0	110.7	S221 G225 H226 I227	S221-D223 PolarHBondContact OG-N 2.93Å; D223-G225 PolarHBondContact O-N 3.31Å; D223-G225 VanDerWaalsContact OD2-CA 3.31Å; D223-G225 WeakPolarHBondContact OD2-CA 3.41Å; D223-G225 PolarHBondContact OD2-N 2.76Å; D223-H226 HydrophobicContact CB-CB 4.24Å; D223-H226 PolarHBondContact O-N 2.6Å; D223-H226 IonicContact OD2-CD2 2.84Å; D223-H226 PolarHBondContact OD2-CD2 2.93Å; D223-H226 IonicContact OD2-CG 2.88Å; D223-H226 PolarHBondContact OD2-N 3.16Å; D223-I227 WeakPolarHBondContact O-CG1 3.44Å; D223-I227 PolarHBondContact O-N 3.36Å; D223-I227 VanDerWaalsContact O-N 3.12Å
224	P	89	Confident	91.4	Very high	61 Å²	61	48.4 Å²	48.4	40%	0.396	28%	0.275	S	S	.	.	H	α-helix	trans	-58.3	-30.8	177.3	-24.9	35.1	0	0	0	113.2	Q222 I227 A228	Q222-P224 WeakPolarHBondContact O-CD 3.36Å; P224-I227 PolarHBondContact O-N 3.37Å; P224-A228 PolarHBondContact O-N 3.5Å
225	G	89.2	Confident	91.7	Very high	0 Å²	0	42.5 Å²	42.5	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-62.3	-52.3	177	0	0	0	0	0	112.4	D223 I227 A228 L229 S437	D223-G225 PolarHBondContact O-N 3.31Å; D223-G225 VanDerWaalsContact OD2-CA 3.31Å; D223-G225 WeakPolarHBondContact OD2-CA 3.41Å; D223-G225 PolarHBondContact OD2-N 2.76Å; G225-I227 VanDerWaalsContact C-N 3.31Å; G225-I227 PolarHBondContact O-N 2.96Å; G225-A228 PolarHBondContact O-N 3.05Å; G225-L229 WeakPolarHBondContact O-CG 3.38Å; G225-L229 PolarHBondContact O-N 3.28Å; G225-S437 WeakPolarHBondContact CA-OG 3.42Å
226	H	92.1	Very high	92.1	Very high	84 Å²	84	40.9 Å²	40.9	39%	0.389	23%	0.225	S	C	.	.	H	α-helix	trans	-57.6	-43	173.3	-71.7	-170.7	0	0	0	112.1	H64 S221 D223 A228 L229 A230	H64-H226 HydrophobicContact CB-CB 4.27Å; H64-H226 VanDerWaalsContact CB-O 3.31Å; H64-H226 WeakPolarHBondContact CB-O 3.39Å; S221-H226 WeakPolarHBondContact OG-CB 3.35Å; S221-H226 PolarHBondContact OG-ND1 3.1Å; D223-H226 HydrophobicContact CB-CB 4.24Å; D223-H226 PolarHBondContact O-N 2.6Å; D223-H226 IonicContact OD2-CD2 2.84Å; D223-H226 PolarHBondContact OD2-CD2 2.93Å; D223-H226 IonicContact OD2-CG 2.88Å; D223-H226 PolarHBondContact OD2-N 3.16Å; H226-A228 VanDerWaalsContact C-N 3.31Å; H226-A228 PolarHBondContact O-N 3.28Å; H226-L229 PolarHBondContact O-N 3.08Å; H226-A230 WeakPolarHBondContact O-CB 3.41Å; H226-A230 PolarHBondContact O-N 3.27Å
227	I	92.9	Very high	92.2	Very high	48 Å²	48	38.2 Å²	38.2	25%	0.246	21%	0.211	C	C	.	.	H	α-helix	trans	-61.8	-39.9	178.3	-64.7	168.3	0	0	0	111.2	D223 P224 G225 A230 L231	D223-I227 WeakPolarHBondContact O-CG1 3.44Å; D223-I227 PolarHBondContact O-N 3.36Å; D223-I227 VanDerWaalsContact O-N 3.12Å; P224-I227 PolarHBondContact O-N 3.37Å; G225-I227 VanDerWaalsContact C-N 3.31Å; G225-I227 PolarHBondContact O-N 2.96Å; I227-A230 PolarHBondContact O-N 3.1Å; I227-L231 HydrophobicContact CG2-CD1 4.28Å; I227-L231 WeakPolarHBondContact O-CB 3.38Å; I227-L231 WeakPolarHBondContact O-CG 3.49Å; I227-L231 PolarHBondContact O-N 3.22Å
228	A	91.3	Very high	92.1	Very high	0 Å²	0	32.8 Å²	32.8	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-66.1	-40.2	176.5	0	0	0	0	0	112.7	P224 G225 H226 L231 Y232 F429 V433 P434	P224-A228 PolarHBondContact O-N 3.5Å; G225-A228 PolarHBondContact O-N 3.05Å; H226-A228 VanDerWaalsContact C-N 3.31Å; H226-A228 PolarHBondContact O-N 3.28Å; A228-L231 WeakPolarHBondContact O-CB 3.22Å; A228-L231 PolarHBondContact O-N 3.47Å; A228-Y232 WeakPolarHBondContact O-CD1 3.39Å; A228-Y232 PolarHBondContact O-N 3.5Å; A228-F429 HydrophobicContact CB-CE1 4.04Å; A228-F429 HydrophobicContact CB-CZ 4.26Å; A228-V433 HydrophobicContact CB-CB 3.94Å; A228-V433 HydrophobicContact CB-CG1 3.38Å; A228-P434 HydrophobicContact CB-CG 4.23Å
229	L	91.3	Very high	92	Very high	14 Å²	14	27.7 Å²	27.7	7%	0.073	16%	0.162	C	C	.	.	H	α-helix	trans	-69.1	-35.1	175.8	-64.6	176.6	0	0	0	112.3	G225 H226 Y232 S233 D438	G225-L229 WeakPolarHBondContact O-CG 3.38Å; G225-L229 PolarHBondContact O-N 3.28Å; H226-L229 PolarHBondContact O-N 3.08Å; L229-Y232 HydrophobicContact CD2-CD2 4.33Å; L229-Y232 WeakPolarHBondContact O-CB 3.26Å; L229-Y232 PolarHBondContact O-N 3.27Å; L229-S233 PolarHBondContact O-N 3.33Å; L229-S233 VanDerWaalsContact O-N 3.09Å; L229-S233 PolarHBondContact O-OG 3.09Å; L229-D438 HydrophobicContact CD2-CB 4.38Å
230	A	94.8	Very high	91.7	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-61.7	-45.7	170	0	0	0	0	0	110.6	V61 H64 V74 H226 I227 Y232 S233 A234	V61-A230 HydrophobicContact CG1-CB 4.41Å; H64-A230 HydrophobicContact CB-CB 3.8Å; V74-A230 HydrophobicContact CG1-CB 4.01Å; V74-A230 HydrophobicContact CG2-CB 4.2Å; H226-A230 WeakPolarHBondContact O-CB 3.41Å; H226-A230 PolarHBondContact O-N 3.27Å; I227-A230 PolarHBondContact O-N 3.1Å; A230-Y232 VanDerWaalsContact C-N 3.34Å; A230-Y232 PolarHBondContact O-N 3.17Å; A230-S233 WeakPolarHBondContact O-CB 3.18Å; A230-S233 PolarHBondContact O-N 3.4Å; A230-A234 PolarHBondContact O-N 2.75Å
231	L	94.6	Very high	91.4	Very high	18 Å²	18	24.3 Å²	24.3	9%	0.094	13%	0.13	C	C	.	.	H	α-helix	trans	-61.2	-40.6	175	-80	166.7	0	0	0	111.7	V74 I77 I227 A228 S233 A234 L235 F429 L430	V74-L231 HydrophobicContact CG1-CD2 3.97Å; V74-L231 HydrophobicContact CG1-CG 4.13Å; I77-L231 HydrophobicContact CB-CD2 4.35Å; I77-L231 HydrophobicContact CG2-CD2 3.94Å; I227-L231 HydrophobicContact CG2-CD1 4.28Å; I227-L231 WeakPolarHBondContact O-CB 3.38Å; I227-L231 WeakPolarHBondContact O-CG 3.49Å; I227-L231 PolarHBondContact O-N 3.22Å; A228-L231 WeakPolarHBondContact O-CB 3.22Å; A228-L231 PolarHBondContact O-N 3.47Å; L231-S233 VanDerWaalsContact C-N 3.32Å; L231-S233 PolarHBondContact O-N 3.4Å; L231-A234 PolarHBondContact O-N 3.37Å; L231-L235 HydrophobicContact CB-CD1 4.47Å; L231-L235 WeakPolarHBondContact O-CB 3.28Å; L231-L235 WeakPolarHBondContact O-CG 3.42Å; L231-L235 PolarHBondContact O-N 3.47Å; L231-F429 HydrophobicContact CD1-CE1 4.07Å; L231-L430 HydrophobicContact CB-CD2 4.05Å; L231-L430 HydrophobicContact CD1-CD2 4.35Å
232	Y	93.1	Very high	91.1	Very high	2 Å²	2	24 Å²	24	1%	0.008	13%	0.127	C	C	.	.	H	α-helix	trans	-56.4	-47.2	173.6	-83.3	12.6	0	0	0	112	A228 L229 A230 A234 L235 F236 N382 F386 L430 P434	A228-Y232 WeakPolarHBondContact O-CD1 3.39Å; A228-Y232 PolarHBondContact O-N 3.5Å; L229-Y232 HydrophobicContact CD2-CD2 4.33Å; L229-Y232 WeakPolarHBondContact O-CB 3.26Å; L229-Y232 PolarHBondContact O-N 3.27Å; A230-Y232 VanDerWaalsContact C-N 3.34Å; A230-Y232 PolarHBondContact O-N 3.17Å; Y232-A234 PolarHBondContact O-N 3.3Å; Y232-L235 PolarHBondContact O-N 3.29Å; Y232-F236 WeakPolarHBondContact O-CB 3.41Å; Y232-F236 PolarHBondContact O-N 2.9Å; Y232-N382 HydrophobicContact CD2-CB 4.45Å; Y232-F386 HydrophobicContact CE2-CB 4.2Å; Y232-F386 WeakPolarHBondContact OH-CA 3.19Å; Y232-L430 HydrophobicContact CD1-CD2 4.04Å; Y232-L430 HydrophobicContact CE1-CB 4.06Å; Y232-L430 HydrophobicContact CE1-CD2 3.95Å; Y232-L430 VanDerWaalsContact CE1-O 3.29Å; Y232-L430 WeakPolarHBondContact CE1-O 3.28Å; Y232-L430 VanDerWaalsContact CZ-O 3.24Å; Y232-L430 PolarHBondContact OH-O 2.87Å; Y232-P434 HydrophobicContact CE1-CG 4.07Å; Y232-P434 HydrophobicContact CE2-CB 4.07Å; Y232-P434 HydrophobicContact CE2-CG 3.85Å; Y232-P434 WeakPolarHBondContact OH-CG 3.27Å
233	S	94	Very high	90.5	Very high	0 Å²	0	17.8 Å²	17.8	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-60.2	-46	177.2	-66.5	0	0	0	0	111.6	S57 L229 A230 L231	S57-S233 WeakPolarHBondContact CB-O 3.46Å; S57-S233 PolarHBondContact OG-O 3.49Å; L229-S233 PolarHBondContact O-N 3.33Å; L229-S233 VanDerWaalsContact O-N 3.09Å; L229-S233 PolarHBondContact O-OG 3.09Å; A230-S233 WeakPolarHBondContact O-CB 3.18Å; A230-S233 PolarHBondContact O-N 3.4Å; L231-S233 VanDerWaalsContact C-N 3.32Å; L231-S233 PolarHBondContact O-N 3.4Å
234	A	95.4	Very high	89.8	Confident	0 Å²	0	14.6 Å²	14.6	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-65.7	-44	177	0	0	0	0	0	112.1	V61 V74 W75 A230 L231 Y232 F236 S237 Y238	V61-A234 HydrophobicContact CG2-CB 3.92Å; V74-A234 HydrophobicContact CG1-CB 4.01Å; W75-A234 HydrophobicContact CD2-CB 4.33Å; W75-A234 HydrophobicContact CE3-CB 4.31Å; A230-A234 PolarHBondContact O-N 2.75Å; L231-A234 PolarHBondContact O-N 3.37Å; Y232-A234 PolarHBondContact O-N 3.3Å; A234-F236 VanDerWaalsContact C-N 3.3Å; A234-F236 PolarHBondContact O-N 2.92Å; A234-S237 VanDerWaalsContact O-CB 3.3Å; A234-S237 WeakPolarHBondContact O-CB 3.25Å; A234-S237 PolarHBondContact O-N 3.33Å; A234-Y238 VanDerWaalsContact O-CD2 3.28Å; A234-Y238 WeakPolarHBondContact O-CD2 3.33Å; A234-Y238 PolarHBondContact O-N 2.99Å; A234-Y238 VanDerWaalsContact O-N 3.16Å
235	L	93.7	Very high	89.5	Confident	1 Å²	1	11.7 Å²	11.7	1%	0.005	6%	0.064	C	C	.	.	H	α-helix	trans	-68.7	-27.3	-177.6	-74.8	178.3	0	0	0	113.2	F81 L231 Y232 S237 Y238 S239 W389 L430	F81-L235 HydrophobicContact CD1-CD1 3.98Å; F81-L235 HydrophobicContact CD1-CD2 3.42Å; F81-L235 VanDerWaalsContact CD1-CD2 3.42Å; F81-L235 HydrophobicContact CD1-CG 4.37Å; F81-L235 HydrophobicContact CE1-CD1 3.86Å; F81-L235 HydrophobicContact CE1-CD2 3.95Å; F81-L235 HydrophobicContact CG-CD2 4.37Å; L231-L235 HydrophobicContact CB-CD1 4.47Å; L231-L235 WeakPolarHBondContact O-CB 3.28Å; L231-L235 WeakPolarHBondContact O-CG 3.42Å; L231-L235 PolarHBondContact O-N 3.47Å; Y232-L235 PolarHBondContact O-N 3.29Å; L235-S237 VanDerWaalsContact C-N 3.31Å; L235-Y238 CarbonylContact O-C 3.22Å; L235-Y238 PolarHBondContact O-N 3.36Å; L235-S239 PolarHBondContact O-N 2.98Å; L235-W389 HydrophobicContact CB-CZ2 3.63Å; L235-W389 HydrophobicContact CD1-CZ2 4.1Å; L235-W389 HydrophobicContact CD2-CH2 4.37Å; L235-W389 HydrophobicContact CD2-CZ2 3.98Å; L235-W389 HydrophobicContact CG-CZ2 4.11Å; L235-L430 HydrophobicContact CD1-CD1 3.48Å; L235-L430 VanDerWaalsContact CD1-CD1 3.48Å; L235-L430 HydrophobicContact CD1-CD2 4.12Å; L235-L430 HydrophobicContact CD1-CG 4.47Å
236	F	93.1	Very high	88.8	Confident	7 Å²	7	14.2 Å²	14.2	3%	0.031	8%	0.076	C	C	.	.	H	α-helix	trans	-58.1	-45	167.5	179.9	-103.7	0	0	0	111.2	V133 Y232 A234 Y238 S239 I381 Y384	V133-F236 HydrophobicContact CB-CZ 3.99Å; V133-F236 HydrophobicContact CG1-CE1 3.67Å; V133-F236 HydrophobicContact CG1-CE2 4.43Å; V133-F236 HydrophobicContact CG1-CZ 3.48Å; V133-F236 VanDerWaalsContact CG1-CZ 3.48Å; Y232-F236 WeakPolarHBondContact O-CB 3.41Å; Y232-F236 PolarHBondContact O-N 2.9Å; A234-F236 VanDerWaalsContact C-N 3.3Å; A234-F236 PolarHBondContact O-N 2.92Å; F236-Y238 VanDerWaalsContact C-N 3.3Å; F236-Y238 PolarHBondContact O-N 3.49Å; F236-S239 WeakPolarHBondContact O-CB 3.44Å; F236-S239 PolarHBondContact O-N 3Å; F236-S239 PolarHBondContact O-OG 2.81Å; F236-I381 HydrophobicContact CB-CG2 3.84Å; F236-I381 HydrophobicContact CD1-CD1 4.22Å; F236-I381 HydrophobicContact CD1-CG1 4.23Å; F236-I381 HydrophobicContact CD2-CG1 4.39Å; F236-I381 HydrophobicContact CD2-CG2 4.38Å; F236-I381 HydrophobicContact CE1-CD1 4.49Å; F236-I381 HydrophobicContact CE1-CG1 4.4Å; F236-I381 HydrophobicContact CG-CG1 4.23Å; F236-I381 HydrophobicContact CG-CG2 4.05Å; F236-Y384 AromaticContact CD2-CD1 3.54Å; F236-Y384 HydrophobicContact CD2-CD1 3.54Å; F236-Y384 AromaticContact CD2-CE1 3.61Å; F236-Y384 HydrophobicContact CD2-CE1 3.61Å; F236-Y384 HydrophobicContact CD2-CG 4.35Å; F236-Y384 AromaticContact CE2-CD1 4Å; F236-Y384 HydrophobicContact CE2-CD1 4Å; F236-Y384 HydrophobicContact CE2-CE1 4.08Å; F236-Y384 HydrophobicContact CE2-CG 4.4Å
237	S	93.1	Very high	87.9	Confident	1 Å²	1	10.9 Å²	10.9	1%	0.007	6%	0.061	C	C	.	.	H	α-helix	trans	-66.4	-30.5	175.5	-72.3	0	0	0	0	113.7	G53 I54 S57 W75 A234 L235 S239 Y273	G53-S237 WeakPolarHBondContact CA-OG 3.29Å; G53-S237 PolarHBondContact O-OG 3.3Å; I54-S237 PolarHBondContact N-OG 2.77Å; I54-S237 VanDerWaalsContact N-OG 3.16Å; S57-S237 WeakPolarHBondContact CB-OG 3.16Å; S57-S237 PolarHBondContact OG-OG 2.79Å; W75-S237 WeakPolarHBondContact CH2-OG 3.26Å; A234-S237 VanDerWaalsContact O-CB 3.3Å; A234-S237 WeakPolarHBondContact O-CB 3.25Å; A234-S237 PolarHBondContact O-N 3.33Å; L235-S237 VanDerWaalsContact C-N 3.31Å; S237-S239 VanDerWaalsContact C-N 3.32Å; S237-Y273 VanDerWaalsContact O-CE2 3.26Å; S237-Y273 WeakPolarHBondContact O-CE2 3.49Å; S237-Y273 PolarHBondContact O-OH 3.01Å
238	Y	91.9	Very high	87.1	Confident	0 Å²	0	8.7 Å²	8.7	0%	0	5%	0.05	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84.9	-1.2	175.5	-73.8	-71.6	0	0	0	113.5	M49 W75 S82 A234 L235 F236 V269 Y273	M49-Y238 HydrophobicContact CE-CD1 3.81Å; M49-Y238 VanDerWaalsContact CE-O 3.22Å; M49-Y238 WeakPolarHBondContact CE-O 3.45Å; W75-Y238 HydrophobicContact CE3-CD2 4.49Å; W75-Y238 AromaticContact CE3-CE2 3.69Å; W75-Y238 HydrophobicContact CE3-CE2 3.69Å; W75-Y238 HydrophobicContact CZ3-CE2 4.1Å; W75-Y238 WeakPolarHBondContact O-CE2 3.49Å; W75-Y238 PolarHBondContact O-OH 2.74Å; S82-Y238 VanDerWaalsContact OG-CB 3.31Å; S82-Y238 WeakPolarHBondContact OG-CB 3.39Å; A234-Y238 VanDerWaalsContact O-CD2 3.28Å; A234-Y238 WeakPolarHBondContact O-CD2 3.33Å; A234-Y238 PolarHBondContact O-N 2.99Å; A234-Y238 VanDerWaalsContact O-N 3.16Å; L235-Y238 CarbonylContact O-C 3.22Å; L235-Y238 PolarHBondContact O-N 3.36Å; F236-Y238 VanDerWaalsContact C-N 3.3Å; F236-Y238 PolarHBondContact O-N 3.49Å; Y238-V269 HydrophobicContact CD1-CG1 4.17Å; Y238-V269 HydrophobicContact CE1-CG1 4.15Å; Y238-Y273 AromaticContact CD1-CD2 3.86Å; Y238-Y273 HydrophobicContact CD1-CD2 3.86Å; Y238-Y273 AromaticContact CD1-CE2 3.84Å; Y238-Y273 HydrophobicContact CD1-CE2 3.84Å; Y238-Y273 HydrophobicContact CD2-CD2 4.42Å; Y238-Y273 AromaticContact CE1-CD2 3.45Å; Y238-Y273 HydrophobicContact CE1-CD2 3.45Å; Y238-Y273 VanDerWaalsContact CE1-CD2 3.45Å; Y238-Y273 AromaticContact CE1-CE2 3.91Å; Y238-Y273 HydrophobicContact CE1-CE2 3.91Å; Y238-Y273 HydrophobicContact CE1-CG 4.43Å; Y238-Y273 HydrophobicContact CE2-CD2 4.07Å; Y238-Y273 HydrophobicContact CG-CD2 4.34Å; Y238-Y273 HydrophobicContact CG-CE2 4.21Å; Y238-Y273 AromaticContact CZ-CD2 3.57Å
239	S	87.1	Confident	86.4	Confident	16 Å²	16	12.3 Å²	12.3	11%	0.112	7%	0.067	C	C	.	.	T	Hydrogen-bonded Turn	trans	-70.1	156.5	179.1	70	0	0	0	0	112.3	M49 L235 F236 S237 Y384	M49-S239 WeakPolarHBondContact CA-O 3.31Å; L235-S239 PolarHBondContact O-N 2.98Å; F236-S239 WeakPolarHBondContact O-CB 3.44Å; F236-S239 PolarHBondContact O-N 3Å; F236-S239 PolarHBondContact O-OG 2.81Å; S237-S239 VanDerWaalsContact C-N 3.32Å; S239-Y384 WeakPolarHBondContact CB-OH 3.23Å; S239-Y384 PolarHBondContact OG-OH 2.89Å
240	G	82.6	Confident	85.8	Confident	14 Å²	14	13.7 Å²	13.7	14%	0.144	7%	0.073	C	C	.	.	T	Hydrogen-bonded Turn	trans	103.4	-4.3	178.8	0	0	0	0	0	115.8	D242 T243	G240-D242 WeakPolarHBondContact CA-OD1 3.29Å; G240-D242 PolarHBondContact O-N 3.19Å; G240-T243 WeakPolarHBondContact O-CB 3.38Å; G240-T243 PolarHBondContact O-N 3.24Å; G240-T243 VanDerWaalsContact O-N 3.11Å; G240-T243 PolarHBondContact O-OG1 3.49Å
241	W	86.9	Confident	85.3	Confident	0 Å²	0	13.9 Å²	13.9	0%	0	7%	0.074	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.8	-23.6	172.4	52.1	-107.4	0	0	0	113.3	I45 M49 A86 Y89 T243 M266 W389 V392	I45-W241 HydrophobicContact CG2-CB 4.45Å; M49-W241 HydrophobicContact CE-CB 4.39Å; M49-W241 HydrophobicContact CG-CB 4.45Å; M49-W241 HydrophobicContact SD-CB 3.86Å; A86-W241 VanDerWaalsContact CA-CE3 3.46Å; A86-W241 HydrophobicContact CB-CB 4.24Å; A86-W241 HydrophobicContact CB-CD2 3.8Å; A86-W241 HydrophobicContact CB-CE3 3.63Å; A86-W241 HydrophobicContact CB-CG 4.07Å; A86-W241 HydrophobicContact CB-CZ3 4.3Å; Y89-W241 HydrophobicContact CD1-CH2 4.38Å; Y89-W241 AromaticContact CD1-CZ3 3.81Å; Y89-W241 HydrophobicContact CD1-CZ3 3.81Å; Y89-W241 AromaticContact CD2-CH2 3.64Å; Y89-W241 HydrophobicContact CD2-CH2 3.64Å; Y89-W241 AromaticContact CD2-CZ3 3.65Å; Y89-W241 HydrophobicContact CD2-CZ3 3.65Å; Y89-W241 HydrophobicContact CE1-CZ3 4.38Å; Y89-W241 AromaticContact CE2-CH2 3.91Å; Y89-W241 HydrophobicContact CE2-CH2 3.91Å; Y89-W241 HydrophobicContact CE2-CZ3 4.25Å; Y89-W241 AromaticContact CG-CH2 3.92Å; Y89-W241 HydrophobicContact CG-CH2 3.92Å; Y89-W241 AromaticContact CG-CZ3 3.42Å; Y89-W241 HydrophobicContact CG-CZ3 3.42Å; Y89-W241 VanDerWaalsContact CG-CZ3 3.42Å; W241-T243 VanDerWaalsContact C-N 3.27Å; W241-T243 PolarHBondContact O-N 2.92Å; W241-M266 HydrophobicContact CB-SD 3.64Å; W241-M266 HydrophobicContact CG-SD 4.19Å; W241-W389 HydrophobicContact CZ2-CH2 4.28Å; W241-W389 HydrophobicContact CZ2-CZ3 4.11Å; W241-V392 HydrophobicContact CH2-CG1 4.06Å; W241-V392 HydrophobicContact CZ2-CG1 4.27Å
242	D	85.4	Confident	84.8	Confident	9 Å²	9	17.9 Å²	17.9	5%	0.048	9%	0.09	C	C	.	.	T	Hydrogen-bonded Turn	trans	-78.8	-5.7	176.5	63.2	-35.5	0	0	0	112.9	Y89 G240 L244 N245 F246 Y388	Y89-D242 HydrophobicContact CD1-CB 4.05Å; Y89-D242 HydrophobicContact CE1-CB 4.16Å; G240-D242 WeakPolarHBondContact CA-OD1 3.29Å; G240-D242 PolarHBondContact O-N 3.19Å; D242-L244 VanDerWaalsContact C-N 3.3Å; D242-L244 PolarHBondContact O-N 3.29Å; D242-N245 VanDerWaalsContact O-CB 3.24Å; D242-N245 WeakPolarHBondContact O-CB 3.24Å; D242-N245 PolarHBondContact O-N 2.9Å; D242-F246 WeakPolarHBondContact O-CD2 3.46Å; D242-Y388 VanDerWaalsContact CG-OH 3.22Å; D242-Y388 PolarHBondContact OD1-OH 3.42Å; D242-Y388 PolarHBondContact OD2-OH 2.85Å
243	T	78.2	Confident	84.5	Confident	31 Å²	31	23.5 Å²	23.5	19%	0.19	12%	0.121	C	C	.	.	H	α-helix	trans	-58.6	-40.6	-179.2	-45.5	0	0	0	0	112.1	L44 N48 G240 W241 N245 F246	L44-T243 HydrophobicContact CD2-CG2 3.83Å; N48-T243 WeakPolarHBondContact ND2-CB 3.48Å; N48-T243 WeakPolarHBondContact ND2-CG2 3.41Å; N48-T243 PolarHBondContact ND2-OG1 3.41Å; N48-T243 VanDerWaalsContact ND2-OG1 3.11Å; G240-T243 WeakPolarHBondContact O-CB 3.38Å; G240-T243 PolarHBondContact O-N 3.24Å; G240-T243 VanDerWaalsContact O-N 3.11Å; G240-T243 PolarHBondContact O-OG1 3.49Å; W241-T243 VanDerWaalsContact C-N 3.27Å; W241-T243 PolarHBondContact O-N 2.92Å; T243-N245 PolarHBondContact O-N 2.89Å; T243-N245 VanDerWaalsContact O-N 3.16Å; T243-F246 WeakPolarHBondContact O-CB 3.39Å; T243-F246 PolarHBondContact O-N 3.37Å
244	L	77.4	Confident	84	Confident	1 Å²	1	24.5 Å²	24.5	1%	0.005	13%	0.127	C	C	.	.	H	α-helix	trans	-61	-27.9	179	-79.9	-171.5	0	0	0	112.6	L44 I45 D242 F246 V247 T248 I251 L258 A261	L44-L244 HydrophobicContact CB-CD2 4.26Å; L44-L244 HydrophobicContact CD1-CD2 4.01Å; L44-L244 HydrophobicContact CD2-CD2 3.85Å; L44-L244 HydrophobicContact CD2-CG 4.26Å; L44-L244 HydrophobicContact CG-CD2 4.27Å; I45-L244 HydrophobicContact CD1-CD1 3.34Å; I45-L244 HydrophobicContact CD1-CG 3.92Å; I45-L244 HydrophobicContact CG1-CD1 3.6Å; I45-L244 HydrophobicContact CG1-CG 3.66Å; D242-L244 VanDerWaalsContact C-N 3.3Å; D242-L244 PolarHBondContact O-N 3.29Å; L244-F246 PolarHBondContact O-N 2.78Å; L244-V247 HydrophobicContact CD2-CG2 4.13Å; L244-V247 CarbonylContact O-C 3.57Å; L244-V247 PolarHBondContact O-N 2.97Å; L244-T248 PolarHBondContact O-N 3.46Å; L244-T248 PolarHBondContact O-OG1 3.34Å; L244-I251 HydrophobicContact CB-CD1 4.31Å; L244-I251 HydrophobicContact CD2-CD1 4.2Å; L244-L258 HydrophobicContact CB-CD1 3.55Å; L244-L258 HydrophobicContact CD1-CD1 4.11Å; L244-L258 HydrophobicContact CG-CD1 4.49Å; L244-A261 HydrophobicContact CD1-CB 3.69Å
245	N	82.4	Confident	83.5	Confident	0 Å²	0	30.3 Å²	30.3	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-66.6	-27.3	177	-69.5	94.7	0	0	0	112.6	Y89 A101 Y105 D242 T243 V247 T248	Y89-N245 PolarHBondContact O-ND2 3.42Å; A101-N245 HydrophobicContact CB-CB 3.84Å; Y105-N245 WeakPolarHBondContact OH-CB 3.47Å; Y105-N245 PolarHBondContact OH-ND2 2.99Å; D242-N245 VanDerWaalsContact O-CB 3.24Å; D242-N245 WeakPolarHBondContact O-CB 3.24Å; D242-N245 PolarHBondContact O-N 2.9Å; T243-N245 PolarHBondContact O-N 2.89Å; T243-N245 VanDerWaalsContact O-N 3.16Å; N245-V247 VanDerWaalsContact C-N 3.32Å; N245-T248 VanDerWaalsContact CA-OG1 3.3Å; N245-T248 WeakPolarHBondContact CA-OG1 3.39Å; N245-T248 PolarHBondContact O-OG1 2.92Å
246	F	74.2	Confident	83.3	Confident	53 Å²	53	38.7 Å²	38.7	23%	0.232	19%	0.186	C	C	.	.	H	α-helix	trans	-71.9	-28.1	175.9	-70	-89.1	0	0	0	112.9	S99 G100 A101 D242 T243 L244	S99-F246 PolarHBondContact OG-O 3.43Å; G100-F246 WeakPolarHBondContact O-CE1 3.42Å; A101-F246 HydrophobicContact CB-CD1 3.72Å; A101-F246 HydrophobicContact CB-CD2 3.61Å; A101-F246 HydrophobicContact CB-CE1 3.64Å; A101-F246 HydrophobicContact CB-CE2 3.55Å; A101-F246 HydrophobicContact CB-CG 3.72Å; A101-F246 HydrophobicContact CB-CZ 3.58Å; D242-F246 WeakPolarHBondContact O-CD2 3.46Å; T243-F246 WeakPolarHBondContact O-CB 3.39Å; T243-F246 PolarHBondContact O-N 3.37Å; L244-F246 PolarHBondContact O-N 2.78Å
247	V	73.4	Confident	83.1	Confident	13 Å²	13	39.5 Å²	39.5	8%	0.079	19%	0.19	C	C	.	.	T	Hydrogen-bonded Turn	trans	-109.7	22.6	-177.6	-65.3	0	0	0	0	112.5	I36 L244 N245 E249 E250 I251	I36-V247 HydrophobicContact CD1-CB 4.04Å; I36-V247 HydrophobicContact CD1-CG2 3.85Å; L244-V247 HydrophobicContact CD2-CG2 4.13Å; L244-V247 CarbonylContact O-C 3.57Å; L244-V247 PolarHBondContact O-N 2.97Å; N245-V247 VanDerWaalsContact C-N 3.32Å; V247-E249 PolarHBondContact O-N 3.23Å; V247-E249 VanDerWaalsContact O-N 3.16Å; V247-E250 HydrophobicContact CB-CB 4.49Å; V247-E250 WeakPolarHBondContact O-CB 3.25Å; V247-E250 PolarHBondContact O-N 3.4Å; V247-I251 PolarHBondContact O-N 3.39Å
248	T	76.3	Confident	82.8	Confident	3 Å²	3	39.4 Å²	39.4	2%	0.018	19%	0.19	C	C	.	.	G	3₁₀ helix	trans	-56	-35.5	-177.3	-51.5	0	0	0	0	112.7	L244 N245 E250 I251 P254	L244-T248 PolarHBondContact O-N 3.46Å; L244-T248 PolarHBondContact O-OG1 3.34Å; N245-T248 VanDerWaalsContact CA-OG1 3.3Å; N245-T248 WeakPolarHBondContact CA-OG1 3.39Å; N245-T248 PolarHBondContact O-OG1 2.92Å; T248-E250 PolarHBondContact O-N 3.13Å; T248-I251 PolarHBondContact O-N 3.02Å; T248-P254 HydrophobicContact CG2-CB 3.88Å
249	E	75.2	Confident	82.7	Confident	75 Å²	75	40.3 Å²	40.3	35%	0.35	20%	0.196	S	C	.	.	G	3₁₀ helix	trans	-62.8	-27.2	177.5	-63.1	-176.2	-171.2	0	0	113.1	L32 K34 T97 K98 S99 V247	L32-E249 HydrophobicContact CD1-CB 4.5Å; K34-E249 WeakPolarHBondContact CG-O 3.45Å; T97-E249 WeakPolarHBondContact O-CG 3.24Å; K98-E249 WeakPolarHBondContact CA-OE1 3.34Å; S99-E249 PolarHBondContact N-OE1 3.49Å; V247-E249 PolarHBondContact O-N 3.23Å; V247-E249 VanDerWaalsContact O-N 3.16Å
250	E	80.2	Confident	82.9	Confident	43 Å²	43	42.7 Å²	42.7	20%	0.201	21%	0.207	C	C	.	.	G	3₁₀ helix	trans	-90.4	-7.6	-178.4	-58.6	175.6	-140.1	0	0	112.6	L32 K34 E35 I36 V247 T248 R332	L32-E250 HydrophobicContact CB-CG 4.2Å; L32-E250 HydrophobicContact CD1-CG 4.23Å; K34-E250 CarbonylContact C-O 3.29Å; K34-E250 VanDerWaalsContact CA-O 3.31Å; K34-E250 WeakPolarHBondContact CA-O 3.3Å; E35-E250 PolarHBondContact N-O 3.08Å; I36-E250 HydrophobicContact CD1-CB 3.78Å; I36-E250 HydrophobicContact CG1-CB 4.13Å; I36-E250 PolarHBondContact N-O 3.16Å; V247-E250 HydrophobicContact CB-CB 4.49Å; V247-E250 WeakPolarHBondContact O-CB 3.25Å; V247-E250 PolarHBondContact O-N 3.4Å; T248-E250 PolarHBondContact O-N 3.13Å; E250-R332 IonicContact OE1-NH1 3.85Å
251	I	82.9	Confident	83.2	Confident	5 Å²	5	42 Å²	42	3%	0.026	20%	0.2	C	C	.	.	B	Isolated β-bridge	trans	-80.9	132.3	-177.9	-61.8	174.9	0	0	0	111.1	I36 L244 V247 T248 N253 P254 N257 L258	I36-I251 HydrophobicContact CB-CG1 4.25Å; I36-I251 HydrophobicContact CG2-CG1 4.26Å; L244-I251 HydrophobicContact CB-CD1 4.31Å; L244-I251 HydrophobicContact CD2-CD1 4.2Å; V247-I251 PolarHBondContact O-N 3.39Å; T248-I251 PolarHBondContact O-N 3.02Å; I251-N253 PolarHBondContact O-N 3.03Å; I251-P254 HydrophobicContact CB-CB 4.36Å; I251-P254 HydrophobicContact CG2-CB 4.35Å; I251-N257 HydrophobicContact CG2-CB 4.06Å; I251-L258 HydrophobicContact CD1-CD1 4.07Å
252	K	84.7	Confident	83.4	Confident	101 Å²	101	42.1 Å²	42.1	44%	0.439	20%	0.201	S	C	.	.	S	Bend	trans	-69.2	125.8	168.3	-66.6	179.3	179.3	177	0	109.1	K34 I36 N257	K34-K252 HydrophobicContact CB-CG 4.36Å; K34-K252 WeakPolarHBondContact O-CE 3.29Å; K34-K252 VanDerWaalsContact O-CG 3.31Å; K34-K252 WeakPolarHBondContact O-CG 3.28Å; I36-K252 PolarHBondContact O-N 3.09Å; K252-N257 WeakPolarHBondContact O-CB 3.43Å; K252-N257 PolarHBondContact O-ND2 3.37Å
253	N	85.9	Confident	83.6	Confident	121 Å²	121	44.3 Å²	44.3	65%	0.647	22%	0.22	S	C	*	.	S	Bend	trans	48.5	64.3	179.8	-61.8	-20.1	0	0	0	113.1	I251 E255 R256 N257	I251-N253 PolarHBondContact O-N 3.03Å; N253-E255 PolarHBondContact O-N 3.34Å; N253-R256 PolarHBondContact O-N 3.07Å; N253-R256 VanDerWaalsContact O-N 3.14Å; N253-N257 WeakPolarHBondContact O-CB 3.35Å; N253-N257 PolarHBondContact O-N 2.92Å
254	P	84.1	Confident	84.2	Confident	21 Å²	21	46.4 Å²	46.4	14%	0.136	23%	0.229	C	C	.	.	H	α-helix	trans	-57.9	-36	-171.7	23.5	-33.2	0	0	0	112.7	T248 I251 R256 L258	T248-P254 HydrophobicContact CG2-CB 3.88Å; I251-P254 HydrophobicContact CB-CB 4.36Å; I251-P254 HydrophobicContact CG2-CB 4.35Å; P254-R256 PolarHBondContact O-N 2.8Å; P254-L258 WeakPolarHBondContact O-CB 3.48Å; P254-L258 PolarHBondContact O-N 3.29Å
255	E	85.6	Confident	84.9	Confident	122 Å²	122	46.3 Å²	46.3	57%	0.57	23%	0.229	S	C	*	.	H	α-helix	trans	-56	-34.8	179.6	-58	-179.2	179.2	0	0	113.9	N253 P259 P412	N253-E255 PolarHBondContact O-N 3.34Å; E255-P259 WeakPolarHBondContact O-CD 3.44Å; E255-P259 WeakPolarHBondContact O-CG 3.48Å; E255-P412 HydrophobicContact CB-CB 3.95Å; E255-P412 VanDerWaalsContact CD-CB 3.42Å; E255-P412 HydrophobicContact CG-CB 3.53Å; E255-P412 HydrophobicContact CG-CG 3.86Å; E255-P412 WeakPolarHBondContact OE1-CG 3.45Å
256	R	88.3	Confident	85.3	Confident	176 Å²	176	46.3 Å²	46.3	66%	0.664	23%	0.229	S	C	*	.	H	α-helix	trans	-100.6	-43.4	180	-179.7	177.7	174.4	-170.9	-0.4	111.9	N253 P254 P259 L260	N253-R256 PolarHBondContact O-N 3.07Å; N253-R256 VanDerWaalsContact O-N 3.14Å; P254-R256 PolarHBondContact O-N 2.8Å; R256-P259 WeakPolarHBondContact O-CD 3.47Å; R256-L260 HydrophobicContact CG-CD1 3.65Å; R256-L260 WeakPolarHBondContact O-CB 3.48Å; R256-L260 WeakPolarHBondContact O-CD1 3.18Å; R256-L260 WeakPolarHBondContact O-CG 3.49Å; R256-L260 PolarHBondContact O-N 3.21Å
257	N	89.4	Confident	86.2	Confident	24 Å²	24	47 Å²	47	13%	0.128	24%	0.238	C	C	.	.	H	α-helix	trans	-79.4	-31.8	-170.5	-74.5	-8.3	0	0	0	112.8	L38 I251 K252 N253 A261	L38-N257 HydrophobicContact CB-CB 4.43Å; L38-N257 HydrophobicContact CD1-CB 4.27Å; L38-N257 WeakPolarHBondContact CD1-O 3.49Å; I251-N257 HydrophobicContact CG2-CB 4.06Å; K252-N257 WeakPolarHBondContact O-CB 3.43Å; K252-N257 PolarHBondContact O-ND2 3.37Å; N253-N257 WeakPolarHBondContact O-CB 3.35Å; N253-N257 PolarHBondContact O-N 2.92Å; N257-A261 WeakPolarHBondContact O-CB 3.45Å; N257-A261 PolarHBondContact O-N 3.48Å
258	L	87.5	Confident	87	Confident	0 Å²	0	49.8 Å²	49.8	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-64.8	-51.2	177.2	179	70.7	0	0	0	111.4	T94 L244 I251 P254 L260 A261 I262	T94-L258 HydrophobicContact CG2-CD2 4.29Å; L244-L258 HydrophobicContact CB-CD1 3.55Å; L244-L258 HydrophobicContact CD1-CD1 4.11Å; L244-L258 HydrophobicContact CG-CD1 4.49Å; I251-L258 HydrophobicContact CD1-CD1 4.07Å; P254-L258 WeakPolarHBondContact O-CB 3.48Å; P254-L258 PolarHBondContact O-N 3.29Å; L258-L260 PolarHBondContact O-N 2.9Å; L258-A261 PolarHBondContact O-N 3.45Å; L258-I262 HydrophobicContact CD1-CD1 4.26Å; L258-I262 HydrophobicContact CG-CD1 4.32Å; L258-I262 PolarHBondContact O-N 2.92Å
259	P	89.4	Confident	87.8	Confident	19 Å²	19	49.6 Å²	49.6	12%	0.123	25%	0.251	C	S	.	.	H	α-helix	trans	-66.6	-38.1	179.4	-20.5	34.7	0	0	0	112.6	A90 T94 E255 R256 I262 A263 L413	A90-P259 HydrophobicContact CB-CB 4.42Å; A90-P259 HydrophobicContact CB-CG 4.32Å; T94-P259 HydrophobicContact CG2-CG 4.49Å; E255-P259 WeakPolarHBondContact O-CD 3.44Å; E255-P259 WeakPolarHBondContact O-CG 3.48Å; R256-P259 WeakPolarHBondContact O-CD 3.47Å; P259-I262 PolarHBondContact O-N 2.81Å; P259-A263 VanDerWaalsContact O-CB 3.32Å; P259-A263 WeakPolarHBondContact O-CB 3.2Å; P259-A263 PolarHBondContact O-N 2.91Å; P259-L413 HydrophobicContact CB-CD1 4.32Å; P259-L413 HydrophobicContact CB-CD2 4.19Å; P259-L413 HydrophobicContact CG-CD1 4.08Å; P259-L413 HydrophobicContact CG-CD2 3.82Å; P259-L413 HydrophobicContact CG-CG 4.42Å
260	L	90.2	Very high	88.7	Confident	65 Å²	65	47 Å²	47	34%	0.34	24%	0.24	S	C	.	.	H	α-helix	trans	-65.8	-40.5	177.2	-73.3	175.1	0	0	0	112.1	L38 R256 L258 I262 A263 I264	L38-L260 HydrophobicContact CD1-CB 3.7Å; L38-L260 HydrophobicContact CD2-CB 4.46Å; L38-L260 HydrophobicContact CD2-CD1 4.41Å; R256-L260 HydrophobicContact CG-CD1 3.65Å; R256-L260 WeakPolarHBondContact O-CB 3.48Å; R256-L260 WeakPolarHBondContact O-CD1 3.18Å; R256-L260 WeakPolarHBondContact O-CG 3.49Å; R256-L260 PolarHBondContact O-N 3.21Å; L258-L260 PolarHBondContact O-N 2.9Å; L260-I262 VanDerWaalsContact C-N 3.3Å; L260-I262 PolarHBondContact O-N 3.35Å; L260-A263 PolarHBondContact O-N 2.95Å; L260-I264 VanDerWaalsContact O-CG1 3.29Å; L260-I264 WeakPolarHBondContact O-CG1 2.96Å; L260-I264 PolarHBondContact O-N 3.03Å
261	A	90.8	Very high	89.4	Confident	1 Å²	1	48.9 Å²	48.9	1%	0.008	25%	0.254	C	S	.	.	H	α-helix	trans	-60.2	-43.4	176.9	0	0	0	0	0	111	L38 V42 I45 L244 N257 L258 S265	L38-A261 HydrophobicContact CD1-CB 4.04Å; V42-A261 HydrophobicContact CG2-CB 4.14Å; I45-A261 HydrophobicContact CD1-CB 4.17Å; L244-A261 HydrophobicContact CD1-CB 3.69Å; N257-A261 WeakPolarHBondContact O-CB 3.45Å; N257-A261 PolarHBondContact O-N 3.48Å; L258-A261 PolarHBondContact O-N 3.45Å; A261-S265 VanDerWaalsContact O-CB 3.24Å; A261-S265 WeakPolarHBondContact O-CB 3.5Å; A261-S265 PolarHBondContact O-N 3.47Å; A261-S265 PolarHBondContact O-OG 3.41Å
262	I	90.2	Very high	89.9	Confident	1 Å²	1	49.9 Å²	49.9	1%	0.005	26%	0.26	C	S	.	.	H	α-helix	trans	-65.6	-47.7	176.3	-70.8	166.8	0	0	0	111.2	I45 A86 A90 L258 P259 L260 I264 S265 M266	I45-I262 HydrophobicContact CD1-CG1 3.68Å; A86-I262 HydrophobicContact CB-CD1 4.48Å; A86-I262 HydrophobicContact CB-CG2 3.43Å; A86-I262 VanDerWaalsContact CB-CG2 3.43Å; A90-I262 HydrophobicContact CB-CD1 3.78Å; L258-I262 HydrophobicContact CD1-CD1 4.26Å; L258-I262 HydrophobicContact CG-CD1 4.32Å; L258-I262 PolarHBondContact O-N 2.92Å; P259-I262 PolarHBondContact O-N 2.81Å; L260-I262 VanDerWaalsContact C-N 3.3Å; L260-I262 PolarHBondContact O-N 3.35Å; I262-I264 PolarHBondContact O-N 2.85Å; I262-S265 WeakPolarHBondContact CA-OG 3.22Å; I262-S265 PolarHBondContact O-N 2.62Å; I262-S265 PolarHBondContact O-OG 2.96Å; I262-M266 HydrophobicContact CG2-CG 3.93Å; I262-M266 WeakPolarHBondContact O-CB 3.31Å; I262-M266 VanDerWaalsContact O-CG 3.27Å; I262-M266 WeakPolarHBondContact O-CG 3.42Å; I262-M266 PolarHBondContact O-N 3.31Å
263	A	89.3	Confident	90.4	Very high	55 Å²	55	45 Å²	45	46%	0.455	24%	0.239	S	C	.	.	H	α-helix	trans	-61.6	-30.5	-178.5	0	0	0	0	0	113.1	P259 L260 P267	P259-A263 VanDerWaalsContact O-CB 3.32Å; P259-A263 WeakPolarHBondContact O-CB 3.2Å; P259-A263 PolarHBondContact O-N 2.91Å; L260-A263 PolarHBondContact O-N 2.95Å; A263-P267 WeakPolarHBondContact O-CD 3.27Å; A263-P267 VanDerWaalsContact O-CG 3.31Å; A263-P267 WeakPolarHBondContact O-CG 3.06Å
264	I	91.6	Very high	90.8	Very high	75 Å²	75	41.3 Å²	41.3	39%	0.385	22%	0.218	S	C	.	.	H	α-helix	trans	-84	-47.1	176.9	-65.3	167.1	0	0	0	111.2	V42 L260 I262 I268	V42-I264 HydrophobicContact CG1-CG2 4.1Å; V42-I264 HydrophobicContact CG2-CB 4.18Å; V42-I264 HydrophobicContact CG2-CD1 4.44Å; V42-I264 HydrophobicContact CG2-CG2 4.16Å; L260-I264 VanDerWaalsContact O-CG1 3.29Å; L260-I264 WeakPolarHBondContact O-CG1 2.96Å; L260-I264 PolarHBondContact O-N 3.03Å; I262-I264 PolarHBondContact O-N 2.85Å; I264-I268 HydrophobicContact CG2-CD1 3.71Å; I264-I268 VanDerWaalsContact O-CD1 3.27Å; I264-I268 WeakPolarHBondContact O-CD1 3.49Å; I264-I268 VanDerWaalsContact O-CG1 3.24Å; I264-I268 WeakPolarHBondContact O-CG1 3.44Å
265	S	91.3	Very high	91.4	Very high	0 Å²	0	43.1 Å²	43.1	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-69.2	-41.5	-173.3	53.7	0	0	0	0	113.2	I45 A261 I262 I268 V269	I45-S265 WeakPolarHBondContact CD1-OG 3.32Å; I45-S265 VanDerWaalsContact CG2-OG 3.27Å; I45-S265 WeakPolarHBondContact CG2-OG 3.46Å; A261-S265 VanDerWaalsContact O-CB 3.24Å; A261-S265 WeakPolarHBondContact O-CB 3.5Å; A261-S265 PolarHBondContact O-N 3.47Å; A261-S265 PolarHBondContact O-OG 3.41Å; I262-S265 WeakPolarHBondContact CA-OG 3.22Å; I262-S265 PolarHBondContact O-N 2.62Å; I262-S265 PolarHBondContact O-OG 2.96Å; S265-I268 PolarHBondContact O-N 3.46Å; S265-V269 WeakPolarHBondContact O-CG2 3.5Å; S265-V269 PolarHBondContact O-N 3.03Å
266	M	91.8	Very high	91.8	Very high	0 Å²	0	37.3 Å²	37.3	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-63.3	-46.3	-173.7	-65.8	-58.8	-56.1	0	0	113.9	M49 V83 A86 W241 I262 V269 T270	M49-M266 HydrophobicContact CE-CE 3.59Å; M49-M266 HydrophobicContact CE-SD 3.6Å; M49-M266 VanDerWaalsContact CE-SD 3.6Å; M49-M266 HydrophobicContact SD-CE 4.41Å; M49-M266 HydrophobicContact SD-SD 3.6Å; M49-M266 VanDerWaalsContact SD-SD 3.6Å; V83-M266 HydrophobicContact CG2-CB 3.63Å; V83-M266 HydrophobicContact CG2-CE 4.34Å; V83-M266 HydrophobicContact CG2-CG 4.34Å; A86-M266 HydrophobicContact CB-CG 4.22Å; A86-M266 HydrophobicContact CB-SD 4.28Å; W241-M266 HydrophobicContact CB-SD 3.64Å; W241-M266 HydrophobicContact CG-SD 4.19Å; I262-M266 HydrophobicContact CG2-CG 3.93Å; I262-M266 WeakPolarHBondContact O-CB 3.31Å; I262-M266 VanDerWaalsContact O-CG 3.27Å; I262-M266 WeakPolarHBondContact O-CG 3.42Å; I262-M266 PolarHBondContact O-N 3.31Å; M266-V269 PolarHBondContact O-N 3.23Å; M266-T270 WeakPolarHBondContact O-CB 3.41Å; M266-T270 PolarHBondContact O-N 3.12Å; M266-T270 PolarHBondContact O-OG1 3.28Å
267	P	91.8	Very high	92.2	Very high	66 Å²	66	28.9 Å²	28.9	43%	0.429	17%	0.168	S	C	.	.	H	α-helix	trans	-63.3	-39.9	174.4	-23.5	35.5	0	0	0	112.7	A263 V269 T270 V271	A263-P267 WeakPolarHBondContact O-CD 3.27Å; A263-P267 VanDerWaalsContact O-CG 3.31Å; A263-P267 WeakPolarHBondContact O-CG 3.06Å; P267-V269 PolarHBondContact O-N 3.05Å; P267-T270 PolarHBondContact O-N 3.37Å; P267-V271 WeakPolarHBondContact O-CG2 3.38Å; P267-V271 PolarHBondContact O-N 3.19Å
268	I	91.3	Very high	92.5	Very high	72 Å²	72	29.1 Å²	29.1	37%	0.369	17%	0.17	S	C	.	.	H	α-helix	trans	-58.7	-50.3	178.6	-69.3	170.9	0	0	0	110.3	I264 S265 T270 V271 I272	I264-I268 HydrophobicContact CG2-CD1 3.71Å; I264-I268 VanDerWaalsContact O-CD1 3.27Å; I264-I268 WeakPolarHBondContact O-CD1 3.49Å; I264-I268 VanDerWaalsContact O-CG1 3.24Å; I264-I268 WeakPolarHBondContact O-CG1 3.44Å; S265-I268 PolarHBondContact O-N 3.46Å; I268-T270 VanDerWaalsContact C-N 3.35Å; I268-T270 PolarHBondContact O-N 2.85Å; I268-V271 PolarHBondContact O-N 3.21Å; I268-I272 HydrophobicContact CG2-CD1 3.72Å; I268-I272 VanDerWaalsContact O-CG1 3.28Å; I268-I272 WeakPolarHBondContact O-CG1 3.43Å; I268-I272 PolarHBondContact O-N 3.47Å
269	V	92.8	Very high	92.8	Very high	0 Å²	0	29.2 Å²	29.2	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-62.8	-43.3	179.7	175.7	0	0	0	0	111	V46 M49 I50 Y238 S265 M266 P267 V271 I272 Y273	V46-V269 HydrophobicContact CG1-CG2 4.48Å; V46-V269 HydrophobicContact CG2-CG2 4.21Å; M49-V269 HydrophobicContact CB-CG1 4.24Å; M49-V269 HydrophobicContact CB-CG2 4.27Å; M49-V269 HydrophobicContact CE-CB 4.25Å; M49-V269 HydrophobicContact CE-CG1 3.85Å; M49-V269 HydrophobicContact CE-CG2 4.48Å; M49-V269 HydrophobicContact SD-CB 4.48Å; M49-V269 HydrophobicContact SD-CG1 4.44Å; M49-V269 HydrophobicContact SD-CG2 4.08Å; I50-V269 HydrophobicContact CD1-CG2 4.28Å; I50-V269 HydrophobicContact CG1-CG1 4.29Å; I50-V269 HydrophobicContact CG1-CG2 4.05Å; Y238-V269 HydrophobicContact CD1-CG1 4.17Å; Y238-V269 HydrophobicContact CE1-CG1 4.15Å; S265-V269 WeakPolarHBondContact O-CG2 3.5Å; S265-V269 PolarHBondContact O-N 3.03Å; M266-V269 PolarHBondContact O-N 3.23Å; P267-V269 PolarHBondContact O-N 3.05Å; V269-V271 PolarHBondContact O-N 3.4Å; V269-I272 PolarHBondContact O-N 3.37Å; V269-Y273 HydrophobicContact CG1-CD1 4.29Å; V269-Y273 HydrophobicContact CG1-CD2 3.88Å; V269-Y273 HydrophobicContact CG1-CE1 3.96Å; V269-Y273 HydrophobicContact CG1-CE2 3.52Å; V269-Y273 HydrophobicContact CG1-CG 4.27Å; V269-Y273 WeakPolarHBondContact O-CB 3.12Å; V269-Y273 PolarHBondContact O-N 3.41Å
270	T	93.8	Very high	93.1	Very high	19 Å²	19	28.3 Å²	28.3	12%	0.117	16%	0.164	C	C	.	.	H	α-helix	trans	-59.8	-46.8	178.6	-55.6	0	0	0	0	111.6	M266 P267 I268 Y273 I274	M266-T270 WeakPolarHBondContact O-CB 3.41Å; M266-T270 PolarHBondContact O-N 3.12Å; M266-T270 PolarHBondContact O-OG1 3.28Å; P267-T270 PolarHBondContact O-N 3.37Å; I268-T270 VanDerWaalsContact C-N 3.35Å; I268-T270 PolarHBondContact O-N 2.85Å; T270-Y273 PolarHBondContact O-N 3.44Å; T270-I274 HydrophobicContact CG2-CD1 3.89Å; T270-I274 VanDerWaalsContact O-CG1 3.32Å; T270-I274 WeakPolarHBondContact O-CG1 3.3Å; T270-I274 PolarHBondContact O-N 3.37Å
271	V	94	Very high	93.3	Very high	83 Å²	83	25.2 Å²	25.2	50%	0.503	15%	0.148	S	C	.	.	H	α-helix	trans	-63.2	-45.6	177.5	170.7	0	0	0	0	110.9	P267 I268 V269 Y273 I274 L275	P267-V271 WeakPolarHBondContact O-CG2 3.38Å; P267-V271 PolarHBondContact O-N 3.19Å; I268-V271 PolarHBondContact O-N 3.21Å; V269-V271 PolarHBondContact O-N 3.4Å; V271-Y273 VanDerWaalsContact C-N 3.32Å; V271-Y273 PolarHBondContact O-N 2.83Å; V271-I274 PolarHBondContact O-N 3.15Å; V271-L275 HydrophobicContact CG1-CD1 3.67Å; V271-L275 HydrophobicContact CG1-CG 4.2Å; V271-L275 WeakPolarHBondContact O-CB 3.12Å; V271-L275 VanDerWaalsContact O-CG 3.25Å; V271-L275 WeakPolarHBondContact O-CG 3.34Å; V271-L275 PolarHBondContact O-N 2.86Å
272	I	93.5	Very high	93.4	Very high	26 Å²	26	25.3 Å²	25.3	13%	0.133	15%	0.149	C	C	.	.	H	α-helix	trans	-59.2	-44.8	177.9	-71.2	169.6	0	0	0	110.7	I50 L194 I198 I268 V269 L275 T276	I50-I272 HydrophobicContact CD1-CD1 3.81Å; I50-I272 HydrophobicContact CD1-CG2 4.33Å; L194-I272 HydrophobicContact CB-CG2 4.43Å; L194-I272 HydrophobicContact CD1-CG2 4.09Å; I198-I272 HydrophobicContact CD1-CG2 4.16Å; I268-I272 HydrophobicContact CG2-CD1 3.72Å; I268-I272 VanDerWaalsContact O-CG1 3.28Å; I268-I272 WeakPolarHBondContact O-CG1 3.43Å; I268-I272 PolarHBondContact O-N 3.47Å; V269-I272 PolarHBondContact O-N 3.37Å; I272-L275 PolarHBondContact O-N 3.09Å; I272-T276 VanDerWaalsContact O-CB 3.28Å; I272-T276 WeakPolarHBondContact O-CB 3.32Å; I272-T276 PolarHBondContact O-N 2.89Å; I272-T276 PolarHBondContact O-OG1 3.09Å
273	Y	95	Very high	93.5	Very high	0 Å²	0	26.2 Å²	26.2	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-67.2	-44	-179.1	-72.9	-2.4	0	0	0	112.8	M49 I50 I54 W75 S237 Y238 V269 T270 V271 T276 N277	M49-Y273 VanDerWaalsContact C-OH 3.25Å; M49-Y273 PolarHBondContact O-OH 3.36Å; I50-Y273 WeakPolarHBondContact CA-OH 3.28Å; I50-Y273 HydrophobicContact CG1-CE1 4.09Å; I54-Y273 HydrophobicContact CB-CD1 4.14Å; I54-Y273 HydrophobicContact CB-CE1 3.75Å; I54-Y273 HydrophobicContact CD1-CD1 3.61Å; I54-Y273 HydrophobicContact CD1-CD2 4.47Å; I54-Y273 HydrophobicContact CD1-CE1 4.1Å; I54-Y273 HydrophobicContact CD1-CG 3.8Å; I54-Y273 HydrophobicContact CG1-CD1 3.71Å; I54-Y273 HydrophobicContact CG1-CE1 3.86Å; I54-Y273 HydrophobicContact CG1-CG 4.42Å; I54-Y273 HydrophobicContact CG2-CE1 4.32Å; W75-Y273 AromaticContact CE3-CD2 4Å; W75-Y273 HydrophobicContact CE3-CD2 4Å; W75-Y273 HydrophobicContact CE3-CG 4.33Å; W75-Y273 AromaticContact CZ3-CD2 3.48Å; W75-Y273 HydrophobicContact CZ3-CD2 3.48Å; W75-Y273 VanDerWaalsContact CZ3-CD2 3.48Å; W75-Y273 HydrophobicContact CZ3-CE2 4.14Å; W75-Y273 AromaticContact CZ3-CG 3.93Å; W75-Y273 HydrophobicContact CZ3-CG 3.93Å; S237-Y273 VanDerWaalsContact O-CE2 3.26Å; S237-Y273 WeakPolarHBondContact O-CE2 3.49Å; S237-Y273 PolarHBondContact O-OH 3.01Å; Y238-Y273 AromaticContact CD1-CD2 3.86Å; Y238-Y273 HydrophobicContact CD1-CD2 3.86Å; Y238-Y273 AromaticContact CD1-CE2 3.84Å; Y238-Y273 HydrophobicContact CD1-CE2 3.84Å; Y238-Y273 HydrophobicContact CD2-CD2 4.42Å; Y238-Y273 AromaticContact CE1-CD2 3.45Å; Y238-Y273 HydrophobicContact CE1-CD2 3.45Å; Y238-Y273 VanDerWaalsContact CE1-CD2 3.45Å; Y238-Y273 AromaticContact CE1-CE2 3.91Å; Y238-Y273 HydrophobicContact CE1-CE2 3.91Å; Y238-Y273 HydrophobicContact CE1-CG 4.43Å; Y238-Y273 HydrophobicContact CE2-CD2 4.07Å; Y238-Y273 HydrophobicContact CG-CD2 4.34Å; Y238-Y273 HydrophobicContact CG-CE2 4.21Å; Y238-Y273 AromaticContact CZ-CD2 3.57Å; V269-Y273 HydrophobicContact CG1-CD1 4.29Å; V269-Y273 HydrophobicContact CG1-CD2 3.88Å; V269-Y273 HydrophobicContact CG1-CE1 3.96Å; V269-Y273 HydrophobicContact CG1-CE2 3.52Å; V269-Y273 HydrophobicContact CG1-CG 4.27Å; V269-Y273 WeakPolarHBondContact O-CB 3.12Å; V269-Y273 PolarHBondContact O-N 3.41Å; T270-Y273 PolarHBondContact O-N 3.44Å; V271-Y273 VanDerWaalsContact C-N 3.32Å; V271-Y273 PolarHBondContact O-N 2.83Å; Y273-T276 PolarHBondContact O-N 3.33Å; Y273-N277 PolarHBondContact O-N 3.42Å; Y273-N277 PolarHBondContact O-ND2 2.87Å
274	I	95.6	Very high	93.7	Very high	42 Å²	42	23.6 Å²	23.6	22%	0.215	13%	0.133	C	C	.	.	H	α-helix	trans	-61.4	-49.5	176	-67.9	169.9	0	0	0	109.9	W75 T76 T270 V271 T276 N277 V278	W75-I274 HydrophobicContact CB-CG1 4.45Å; T76-I274 HydrophobicContact CG2-CD1 4.5Å; T76-I274 WeakPolarHBondContact OG1-CD1 3.24Å; T270-I274 HydrophobicContact CG2-CD1 3.89Å; T270-I274 VanDerWaalsContact O-CG1 3.32Å; T270-I274 WeakPolarHBondContact O-CG1 3.3Å; T270-I274 PolarHBondContact O-N 3.37Å; V271-I274 PolarHBondContact O-N 3.15Å; I274-T276 VanDerWaalsContact C-N 3.3Å; I274-T276 PolarHBondContact O-N 3.47Å; I274-N277 PolarHBondContact O-N 3.46Å; I274-V278 HydrophobicContact CG2-CG2 4.4Å; I274-V278 WeakPolarHBondContact O-CG2 3.48Å; I274-V278 PolarHBondContact O-N 3Å
275	L	95.8	Very high	93.8	Very high	59 Å²	59	23 Å²	23	31%	0.309	13%	0.133	S	C	.	.	H	α-helix	trans	-63.8	-35	-179.8	-69.9	178.5	0	0	0	112.7	I198 V271 I272 V278 A279	I198-L275 HydrophobicContact CD1-CB 3.96Å; I198-L275 HydrophobicContact CG1-CB 3.9Å; I198-L275 HydrophobicContact CG2-CB 3.93Å; I198-L275 HydrophobicContact CG2-CD1 4.05Å; V271-L275 HydrophobicContact CG1-CD1 3.67Å; V271-L275 HydrophobicContact CG1-CG 4.2Å; V271-L275 WeakPolarHBondContact O-CB 3.12Å; V271-L275 VanDerWaalsContact O-CG 3.25Å; V271-L275 WeakPolarHBondContact O-CG 3.34Å; V271-L275 PolarHBondContact O-N 2.86Å; I272-L275 PolarHBondContact O-N 3.09Å; L275-V278 PolarHBondContact O-N 3.27Å; L275-A279 WeakPolarHBondContact O-CB 3.49Å; L275-A279 PolarHBondContact O-N 2.72Å
276	T	94.9	Very high	93.8	Very high	0 Å²	0	25.4 Å²	25.4	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-65.2	-43.7	175.5	-58.2	0	0	0	0	111	I54 L194 V197 I272 Y273 I274 A279 Y280	I54-T276 HydrophobicContact CG1-CG2 4.16Å; L194-T276 HydrophobicContact CD2-CG2 3.95Å; V197-T276 HydrophobicContact CG1-CG2 4.24Å; I272-T276 VanDerWaalsContact O-CB 3.28Å; I272-T276 WeakPolarHBondContact O-CB 3.32Å; I272-T276 PolarHBondContact O-N 2.89Å; I272-T276 PolarHBondContact O-OG1 3.09Å; Y273-T276 PolarHBondContact O-N 3.33Å; I274-T276 VanDerWaalsContact C-N 3.3Å; I274-T276 PolarHBondContact O-N 3.47Å; T276-A279 WeakPolarHBondContact O-CB 3.33Å; T276-A279 PolarHBondContact O-N 3.22Å; T276-Y280 HydrophobicContact CG2-CD2 4.27Å; T276-Y280 HydrophobicContact CG2-CE1 4.39Å; T276-Y280 HydrophobicContact CG2-CE2 3.64Å; T276-Y280 PolarHBondContact O-N 2.91Å
277	N	95.8	Very high	93.7	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-66.9	-40.3	176.2	-77	-80.1	0	0	0	111.8	P58 L72 W75 Y273 I274 A279 Y280 Y281	P58-N277 WeakPolarHBondContact CB-OD1 3.21Å; L72-N277 HydrophobicContact CD2-CB 3.85Å; W75-N277 PolarHBondContact NE1-ND2 3.39Å; W75-N277 PolarHBondContact NE1-OD1 2.91Å; Y273-N277 PolarHBondContact O-N 3.42Å; Y273-N277 PolarHBondContact O-ND2 2.87Å; I274-N277 PolarHBondContact O-N 3.46Å; N277-A279 VanDerWaalsContact C-N 3.29Å; N277-A279 PolarHBondContact O-N 3.33Å; N277-Y280 PolarHBondContact O-N 3.42Å; N277-Y281 HydrophobicContact CB-CE2 4.03Å; N277-Y281 WeakPolarHBondContact O-CD2 3.34Å; N277-Y281 PolarHBondContact O-N 2.83Å; N277-Y281 PolarHBondContact OD1-OH 3.2Å
278	V	95.6	Very high	93.7	Very high	28 Å²	28	28.8 Å²	28.8	17%	0.17	16%	0.164	C	C	.	.	H	α-helix	trans	-57.8	-43.8	172.4	170.2	0	0	0	0	110.6	L72 I205 F213 I274 L275 Y281 T282	L72-V278 HydrophobicContact CD1-CG2 4.06Å; L72-V278 HydrophobicContact CD2-CG2 3.92Å; I205-V278 HydrophobicContact CD1-CG1 3.79Å; F213-V278 HydrophobicContact CZ-CG1 4.12Å; I274-V278 HydrophobicContact CG2-CG2 4.4Å; I274-V278 WeakPolarHBondContact O-CG2 3.48Å; I274-V278 PolarHBondContact O-N 3Å; L275-V278 PolarHBondContact O-N 3.27Å; V278-Y281 PolarHBondContact O-N 3.3Å; V278-T282 WeakPolarHBondContact O-CB 3.47Å; V278-T282 PolarHBondContact O-N 3.31Å; V278-T282 PolarHBondContact O-OG1 3.17Å
279	A	95.1	Very high	93.8	Very high	2 Å²	2	25.3 Å²	25.3	2%	0.017	15%	0.146	C	C	.	.	H	α-helix	trans	-60.5	-46.7	175.7	0	0	0	0	0	111.8	V197 L275 T276 N277 Y281 T282 F299	V197-A279 HydrophobicContact CG1-CB 3.97Å; V197-A279 WeakPolarHBondContact O-CB 3.5Å; L275-A279 WeakPolarHBondContact O-CB 3.49Å; L275-A279 PolarHBondContact O-N 2.72Å; T276-A279 WeakPolarHBondContact O-CB 3.33Å; T276-A279 PolarHBondContact O-N 3.22Å; N277-A279 VanDerWaalsContact C-N 3.29Å; N277-A279 PolarHBondContact O-N 3.33Å; A279-Y281 PolarHBondContact O-N 3.21Å; A279-T282 WeakPolarHBondContact O-CB 3.49Å; A279-T282 PolarHBondContact O-N 3.23Å; A279-F299 HydrophobicContact CB-CE2 4.47Å; A279-F299 HydrophobicContact CB-CZ 4.48Å; A279-F299 WeakPolarHBondContact O-CE2 3.22Å
280	Y	94.6	Very high	93.7	Very high	0 Å²	0	27.7 Å²	27.7	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-59.1	-46.7	175.8	-66.3	-28.6	0	0	0	112.3	P58 V197 T276 N277 T282 V283 L284 V295 A296 F299	P58-Y280 HydrophobicContact CB-CD2 4.34Å; P58-Y280 HydrophobicContact CG-CD2 4.23Å; P58-Y280 HydrophobicContact CG-CE2 4.05Å; V197-Y280 HydrophobicContact CG1-CD1 4.28Å; V197-Y280 HydrophobicContact CG1-CE1 3.78Å; T276-Y280 HydrophobicContact CG2-CD2 4.27Å; T276-Y280 HydrophobicContact CG2-CE1 4.39Å; T276-Y280 HydrophobicContact CG2-CE2 3.64Å; T276-Y280 PolarHBondContact O-N 2.91Å; N277-Y280 PolarHBondContact O-N 3.42Å; Y280-T282 VanDerWaalsContact C-N 3.29Å; Y280-T282 PolarHBondContact O-N 2.73Å; Y280-V283 PolarHBondContact O-N 3.42Å; Y280-L284 WeakPolarHBondContact O-CB 3.42Å; Y280-L284 PolarHBondContact O-N 3.03Å; Y280-V295 HydrophobicContact CD1-CG1 4.38Å; Y280-V295 HydrophobicContact CD2-CG1 3.95Å; Y280-V295 HydrophobicContact CE2-CG1 4.17Å; Y280-V295 HydrophobicContact CG-CG1 4.07Å; Y280-A296 HydrophobicContact CE1-CB 4.24Å; Y280-A296 VanDerWaalsContact OH-CB 3.24Å; Y280-A296 WeakPolarHBondContact OH-CB 3.33Å; Y280-F299 HydrophobicContact CD1-CB 3.86Å; Y280-F299 AromaticContact CD1-CD2 3.8Å; Y280-F299 HydrophobicContact CD1-CD2 3.8Å; Y280-F299 HydrophobicContact CD1-CE2 4.48Å; Y280-F299 AromaticContact CD1-CG 3.83Å; Y280-F299 HydrophobicContact CD1-CG 3.83Å; Y280-F299 HydrophobicContact CE1-CB 3.96Å; Y280-F299 HydrophobicContact CE1-CD1 4.45Å; Y280-F299 HydrophobicContact CE1-CD2 4.45Å; Y280-F299 HydrophobicContact CE1-CG 4.04Å
281	Y	94.5	Very high	93.5	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-70.7	-24.9	-177.4	-56.8	-20.7	0	0	0	113.2	L62 Y68 S71 L72 N212 N277 V278 A279 V283 I289	L62-Y281 HydrophobicContact CD2-CE1 4.4Å; Y68-Y281 AromaticContact CD1-CD1 3.52Å; Y68-Y281 HydrophobicContact CD1-CD1 3.52Å; Y68-Y281 AromaticContact CD1-CD2 3.75Å; Y68-Y281 HydrophobicContact CD1-CD2 3.75Å; Y68-Y281 AromaticContact CD1-CE1 3.85Å; Y68-Y281 HydrophobicContact CD1-CE1 3.85Å; Y68-Y281 HydrophobicContact CD1-CE2 4.04Å; Y68-Y281 AromaticContact CD1-CG 3.48Å; Y68-Y281 HydrophobicContact CD1-CG 3.48Å; Y68-Y281 VanDerWaalsContact CD1-CG 3.48Å; Y68-Y281 AromaticContact CE1-CD1 3.54Å; Y68-Y281 HydrophobicContact CE1-CD1 3.54Å; Y68-Y281 HydrophobicContact CE1-CE1 4.06Å; Y68-Y281 AromaticContact CE1-CG 3.84Å; Y68-Y281 HydrophobicContact CE1-CG 3.84Å; Y68-Y281 HydrophobicContact CG-CD1 4.43Å; Y68-Y281 HydrophobicContact CG-CD2 4.01Å; Y68-Y281 AromaticContact CG-CG 3.96Å; Y68-Y281 HydrophobicContact CG-CG 3.96Å; S71-Y281 WeakPolarHBondContact CB-OH 3.43Å; S71-Y281 PolarHBondContact OG-OH 3.12Å; L72-Y281 HydrophobicContact CD2-CD2 4.23Å; L72-Y281 HydrophobicContact CD2-CE2 3.94Å; L72-Y281 HydrophobicContact CG-CD2 4.27Å; L72-Y281 HydrophobicContact CG-CE2 4.03Å; N212-Y281 WeakPolarHBondContact CB-O 3.31Å; N212-Y281 PolarHBondContact ND2-O 3.35Å; N277-Y281 HydrophobicContact CB-CE2 4.03Å; N277-Y281 WeakPolarHBondContact O-CD2 3.34Å; N277-Y281 PolarHBondContact O-N 2.83Å; N277-Y281 PolarHBondContact OD1-OH 3.2Å; V278-Y281 PolarHBondContact O-N 3.3Å; A279-Y281 PolarHBondContact O-N 3.21Å; Y281-V283 VanDerWaalsContact C-N 3.28Å; Y281-V283 PolarHBondContact O-N 3.39Å; Y281-I289 HydrophobicContact CD1-CD1 3.48Å; Y281-I289 VanDerWaalsContact CD1-CD1 3.48Å; Y281-I289 HydrophobicContact CE1-CD1 3.6Å
282	T	94	Very high	93.3	Very high	4 Å²	4	29.5 Å²	29.5	3%	0.025	17%	0.165	C	C	.	.	H	α-helix	trans	-63.3	-37.3	173.5	-56.9	0	0	0	0	111.5	K204 I205 Y209 F213 V278 A279 Y280	K204-T282 HydrophobicContact CB-CG2 3.75Å; I205-T282 HydrophobicContact CG1-CG2 3.57Å; I205-T282 WeakPolarHBondContact CG1-OG1 3.44Å; Y209-T282 VanDerWaalsContact O-CG2 3.26Å; Y209-T282 WeakPolarHBondContact O-CG2 3.19Å; F213-T282 WeakPolarHBondContact CE2-OG1 3.36Å; V278-T282 WeakPolarHBondContact O-CB 3.47Å; V278-T282 PolarHBondContact O-N 3.31Å; V278-T282 PolarHBondContact O-OG1 3.17Å; A279-T282 WeakPolarHBondContact O-CB 3.49Å; A279-T282 PolarHBondContact O-N 3.23Å; Y280-T282 VanDerWaalsContact C-N 3.29Å; Y280-T282 PolarHBondContact O-N 2.73Å
283	V	92.4	Very high	92.9	Very high	20 Å²	20	32.1 Å²	32.1	12%	0.121	18%	0.18	C	C	.	.	H	α-helix	trans	-103.3	-42.5	-170.3	174.5	0	0	0	0	111.9	K204 Y280 Y281 F299 Q302 V303	K204-V283 HydrophobicContact CB-CG2 4.39Å; K204-V283 HydrophobicContact CG-CG2 4.09Å; Y280-V283 PolarHBondContact O-N 3.42Å; Y281-V283 VanDerWaalsContact C-N 3.28Å; Y281-V283 PolarHBondContact O-N 3.39Å; V283-F299 HydrophobicContact CB-CD2 3.81Å; V283-F299 HydrophobicContact CB-CE2 3.72Å; V283-F299 HydrophobicContact CG1-CD2 4.09Å; V283-F299 HydrophobicContact CG1-CE2 4.27Å; V283-F299 HydrophobicContact CG2-CD2 4.09Å; V283-F299 HydrophobicContact CG2-CE2 3.46Å; V283-F299 VanDerWaalsContact CG2-CE2 3.46Å; V283-F299 HydrophobicContact CG2-CZ 4.29Å; V283-Q302 HydrophobicContact CG1-CB 3.84Å; V283-Q302 VanDerWaalsContact CG1-OE1 3.27Å; V283-Q302 PolarHBondContact O-OE1 3.31Å; V283-V303 HydrophobicContact CB-CG2 4.48Å; V283-V303 HydrophobicContact CG1-CG2 3.71Å; V283-V303 HydrophobicContact CG2-CG2 3.99Å
284	L	92.7	Very high	92.6	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	18%	0.18	C	C	.	.	S	Bend	trans	-99.9	130.7	-171.7	-58.5	179.1	0	0	0	111.3	Y68 N212 Y280 I289 V295 T298 F299 Q302	Y68-L284 PolarHBondContact OH-O 3.23Å; N212-L284 PolarHBondContact ND2-O 2.76Å; Y280-L284 WeakPolarHBondContact O-CB 3.42Å; Y280-L284 PolarHBondContact O-N 3.03Å; L284-I289 HydrophobicContact CB-CD1 4.02Å; L284-I289 HydrophobicContact CB-CG1 3.67Å; L284-I289 HydrophobicContact CD1-CG1 4Å; L284-V295 HydrophobicContact CD1-CG1 3.98Å; L284-T298 HydrophobicContact CD1-CG2 4.41Å; L284-T298 HydrophobicContact CD2-CG2 3.99Å; L284-F299 HydrophobicContact CD1-CB 4.05Å; L284-Q302 VanDerWaalsContact CD2-CD 3.5Å; L284-Q302 HydrophobicContact CD2-CG 4.29Å
285	P	92.8	Very high	92.4	Very high	61 Å²	61	30.2 Å²	30.2	40%	0.396	17%	0.17	S	C	.	.			trans	-71.5	161	167.6	30.8	-34.7	0	0	0	111.5	Y68 N287 A288 I289	Y68-P285 WeakPolarHBondContact OH-CA 3.34Å; P285-N287 VanDerWaalsContact C-N 3.31Å; P285-N287 PolarHBondContact O-N 3.25Å; P285-A288 HydrophobicContact CG-CB 3.81Å; P285-A288 WeakPolarHBondContact O-CB 3.37Å; P285-A288 PolarHBondContact O-N 3.43Å; P285-I289 PolarHBondContact O-N 2.89Å
286	I	91.3	Very high	92.1	Very high	52 Å²	52	27.4 Å²	27.4	27%	0.267	16%	0.155	S	C	.	.	H	α-helix	trans	-52.7	-50.7	-173.4	-67.6	179.1	0	0	0	110.3	L62 Y68 A288 I289 L290	L62-I286 HydrophobicContact CD2-CB 4.45Å; L62-I286 HydrophobicContact CD2-CG1 4.43Å; L62-I286 HydrophobicContact CD2-CG2 4.05Å; L62-I286 HydrophobicContact CG-CG2 4.39Å; Y68-I286 HydrophobicContact CD1-CG1 4.11Å; Y68-I286 HydrophobicContact CE1-CB 4.41Å; Y68-I286 HydrophobicContact CE1-CD1 4.29Å; Y68-I286 HydrophobicContact CE1-CG1 3.37Å; Y68-I286 HydrophobicContact CE2-CD1 4.4Å; Y68-I286 HydrophobicContact CE2-CG1 3.9Å; Y68-I286 WeakPolarHBondContact OH-CG1 3.44Å; Y68-I286 PolarHBondContact OH-N 3.16Å; I286-A288 VanDerWaalsContact C-N 3.28Å; I286-A288 PolarHBondContact O-N 3.43Å; I286-I289 WeakPolarHBondContact O-CB 3.27Å; I286-I289 PolarHBondContact O-N 2.84Å; I286-L290 HydrophobicContact CG2-CD1 3.63Å; I286-L290 HydrophobicContact CG2-CG 4.02Å; I286-L290 WeakPolarHBondContact O-CG 3.4Å; I286-L290 PolarHBondContact O-N 3.16Å
287	N	91.3	Very high	91.8	Very high	112 Å²	112	27.5 Å²	27.5	60%	0.599	16%	0.155	S	C	*	.	H	α-helix	trans	-59.4	-37.9	-177.9	-61.6	-20.6	0	0	0	112.4	P285 I289 L290 D291	P285-N287 VanDerWaalsContact C-N 3.31Å; P285-N287 PolarHBondContact O-N 3.25Å; N287-I289 VanDerWaalsContact C-N 3.29Å; N287-I289 PolarHBondContact O-N 3.44Å; N287-L290 PolarHBondContact O-N 3.45Å; N287-D291 WeakPolarHBondContact O-CB 3.37Å; N287-D291 VanDerWaalsContact O-CG 3.27Å; N287-D291 PolarHBondContact O-N 2.84Å
288	A	91.5	Very high	91.6	Very high	24 Å²	24	28.7 Å²	28.7	20%	0.198	16%	0.163	C	C	.	.	H	α-helix	trans	-66.7	-31.4	177.7	0	0	0	0	0	112.5	P285 I286 S292	P285-A288 HydrophobicContact CG-CB 3.81Å; P285-A288 WeakPolarHBondContact O-CB 3.37Å; P285-A288 PolarHBondContact O-N 3.43Å; I286-A288 VanDerWaalsContact C-N 3.28Å; I286-A288 PolarHBondContact O-N 3.43Å; A288-S292 WeakPolarHBondContact O-CB 3.45Å; A288-S292 PolarHBondContact O-N 3.28Å
289	I	92.5	Very high	91.4	Very high	0 Å²	0	27.4 Å²	27.4	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-74.2	-41.1	174.8	-60	179.1	0	0	0	110.4	L62 Y68 Y281 L284 P285 I286 N287 S292 V295	L62-I289 HydrophobicContact CD2-CB 3.94Å; L62-I289 HydrophobicContact CD2-CD1 4.04Å; L62-I289 HydrophobicContact CD2-CG2 3.86Å; Y68-I289 HydrophobicContact CE1-CD1 4.29Å; Y281-I289 HydrophobicContact CD1-CD1 3.48Å; Y281-I289 VanDerWaalsContact CD1-CD1 3.48Å; Y281-I289 HydrophobicContact CE1-CD1 3.6Å; L284-I289 HydrophobicContact CB-CD1 4.02Å; L284-I289 HydrophobicContact CB-CG1 3.67Å; L284-I289 HydrophobicContact CD1-CG1 4Å; P285-I289 PolarHBondContact O-N 2.89Å; I286-I289 WeakPolarHBondContact O-CB 3.27Å; I286-I289 PolarHBondContact O-N 2.84Å; N287-I289 VanDerWaalsContact C-N 3.29Å; N287-I289 PolarHBondContact O-N 3.44Å; I289-S292 PolarHBondContact O-N 2.83Å; I289-V295 HydrophobicContact CG1-CG1 4.49Å; I289-V295 HydrophobicContact CG2-CG1 4.23Å; I289-V295 HydrophobicContact CG2-CG2 4.08Å
290	L	91.8	Very high	91.1	Very high	49 Å²	49	27.3 Å²	27.3	26%	0.257	15%	0.154	S	C	.	.	H	α-helix	trans	-69.3	-38.3	-179	-63.3	-177.9	0	0	0	112.4	K59 L62 I63 I286 N287 S292	K59-L290 WeakPolarHBondContact CE-O 3.45Å; K59-L290 PolarHBondContact NZ-O 3.27Å; L62-L290 HydrophobicContact CB-CD2 4.28Å; L62-L290 HydrophobicContact CD2-CD2 4.4Å; L62-L290 HydrophobicContact CG-CD2 4.34Å; I63-L290 HydrophobicContact CB-CD2 4.38Å; I63-L290 HydrophobicContact CG1-CD2 3.5Å; I286-L290 HydrophobicContact CG2-CD1 3.63Å; I286-L290 HydrophobicContact CG2-CG 4.02Å; I286-L290 WeakPolarHBondContact O-CG 3.4Å; I286-L290 PolarHBondContact O-N 3.16Å; N287-L290 PolarHBondContact O-N 3.45Å; L290-S292 VanDerWaalsContact C-N 3.32Å
291	D	89.6	Confident	90.8	Very high	135 Å²	135	30.7 Å²	30.7	72%	0.722	17%	0.172	S	C	*	.	H	α-helix	trans	-78.4	-18	179.6	-67.2	-21.5	0	0	0	112.7	N287	N287-D291 WeakPolarHBondContact O-CB 3.37Å; N287-D291 VanDerWaalsContact O-CG 3.27Å; N287-D291 PolarHBondContact O-N 2.84Å
292	S	88.4	Confident	90.5	Very high	6 Å²	6	35.5 Å²	35.5	4%	0.042	20%	0.195	C	C	.	.			trans	-88.2	124.6	-174.8	168.4	0	0	0	0	112.6	K59 A288 I289 L290 A294 V295 T298	K59-S292 VanDerWaalsContact CD-O 3.24Å; K59-S292 WeakPolarHBondContact CD-O 3.25Å; K59-S292 PolarHBondContact NZ-O 3.29Å; A288-S292 WeakPolarHBondContact O-CB 3.45Å; A288-S292 PolarHBondContact O-N 3.28Å; I289-S292 PolarHBondContact O-N 2.83Å; L290-S292 VanDerWaalsContact C-N 3.32Å; S292-A294 VanDerWaalsContact C-N 3.33Å; S292-A294 PolarHBondContact OG-N 2.9Å; S292-A294 PolarHBondContact OG-O 3.14Å; S292-V295 WeakPolarHBondContact OG-CA 3.29Å; S292-V295 PolarHBondContact OG-N 3.14Å; S292-T298 WeakPolarHBondContact CB-OG1 3.32Å; S292-T298 PolarHBondContact OG-OG1 3.11Å
293	D	84.8	Confident	90.2	Very high	81 Å²	81	37.2 Å²	37.2	43%	0.433	21%	0.205	S	C	.	.	S	Bend	trans	-82.4	-11.2	171.9	-69.4	-29.1	0	0	0	113.9	K59	K59-D293 IonicContact NZ-OD1 2.83Å; K59-D293 PolarHBondContact NZ-OD1 2.68Å
294	A	89.3	Confident	89.8	Confident	0 Å²	0	38 Å²	38	0%	0	21%	0.207	C	C	.	.	S	Bend	trans	-137.9	76.6	177	0	0	0	0	0	110.9	Y141 Q144 S292 A296 V297 T298	Y141-A294 HydrophobicContact CD1-CB 4.05Å; Y141-A294 HydrophobicContact CD2-CB 3.89Å; Y141-A294 HydrophobicContact CE1-CB 3.89Å; Y141-A294 HydrophobicContact CE2-CB 3.74Å; Y141-A294 HydrophobicContact CG-CB 4.06Å; Q144-A294 HydrophobicContact CB-CB 4.11Å; Q144-A294 HydrophobicContact CG-CB 4.1Å; S292-A294 VanDerWaalsContact C-N 3.33Å; S292-A294 PolarHBondContact OG-N 2.9Å; S292-A294 PolarHBondContact OG-O 3.14Å; A294-A296 PolarHBondContact O-N 3.23Å; A294-A296 VanDerWaalsContact O-N 3.1Å; A294-V297 HydrophobicContact CB-CB 4.14Å; A294-V297 HydrophobicContact CB-CG2 3.9Å; A294-V297 WeakPolarHBondContact O-CB 3.4Å; A294-V297 PolarHBondContact O-N 2.9Å; A294-T298 PolarHBondContact O-N 3.11Å; A294-T298 PolarHBondContact O-OG1 2.87Å
295	V	91.1	Very high	89.4	Confident	1 Å²	1	40.2 Å²	40.2	1%	0.006	23%	0.229	C	C	.	.	H	α-helix	trans	-53	-39	-170.6	-178.6	0	0	0	0	112.9	K59 Y141 Y280 L284 I289 S292 V297 T298 F299	K59-V295 HydrophobicContact CB-CG2 4.29Å; Y141-V295 PolarHBondContact OH-N 3.26Å; Y280-V295 HydrophobicContact CD1-CG1 4.38Å; Y280-V295 HydrophobicContact CD2-CG1 3.95Å; Y280-V295 HydrophobicContact CE2-CG1 4.17Å; Y280-V295 HydrophobicContact CG-CG1 4.07Å; L284-V295 HydrophobicContact CD1-CG1 3.98Å; I289-V295 HydrophobicContact CG1-CG1 4.49Å; I289-V295 HydrophobicContact CG2-CG1 4.23Å; I289-V295 HydrophobicContact CG2-CG2 4.08Å; S292-V295 WeakPolarHBondContact OG-CA 3.29Å; S292-V295 PolarHBondContact OG-N 3.14Å; V295-V297 VanDerWaalsContact C-N 3.34Å; V295-V297 PolarHBondContact O-N 3.1Å; V295-T298 PolarHBondContact O-N 2.69Å; V295-F299 WeakPolarHBondContact O-CB 3.24Å; V295-F299 PolarHBondContact O-N 3Å
296	A	90.1	Very high	88.8	Confident	0 Å²	0	43.7 Å²	43.7	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-70.2	-29.7	-179.6	0	0	0	0	0	113.2	F55 Y141 Y280 A294 A300 I311	F55-A296 HydrophobicContact CD1-CB 3.82Å; F55-A296 HydrophobicContact CE1-CB 4.09Å; Y141-A296 HydrophobicContact CE1-CB 3.93Å; Y141-A296 PolarHBondContact OH-N 3.45Å; Y280-A296 HydrophobicContact CE1-CB 4.24Å; Y280-A296 VanDerWaalsContact OH-CB 3.24Å; Y280-A296 WeakPolarHBondContact OH-CB 3.33Å; A294-A296 PolarHBondContact O-N 3.23Å; A294-A296 VanDerWaalsContact O-N 3.1Å; A296-A300 WeakPolarHBondContact O-CB 3.29Å; A296-A300 PolarHBondContact O-N 2.78Å; A296-I311 HydrophobicContact CB-CG2 3.83Å
297	V	89.4	Confident	88.2	Confident	2 Å²	2	46.6 Å²	46.6	1%	0.012	26%	0.263	C	S	.	.	H	α-helix	trans	-70.1	-46.2	174.4	-178.8	0	0	0	0	109.4	Y141 Q144 A294 V295 F299 A300 D301 P312	Y141-V297 HydrophobicContact CD1-CG2 3.54Å; Y141-V297 HydrophobicContact CE1-CG2 3.71Å; Q144-V297 HydrophobicContact CB-CG1 4.37Å; Q144-V297 HydrophobicContact CG-CB 4.15Å; Q144-V297 HydrophobicContact CG-CG1 3.85Å; A294-V297 HydrophobicContact CB-CB 4.14Å; A294-V297 HydrophobicContact CB-CG2 3.9Å; A294-V297 WeakPolarHBondContact O-CB 3.4Å; A294-V297 PolarHBondContact O-N 2.9Å; V295-V297 VanDerWaalsContact C-N 3.34Å; V295-V297 PolarHBondContact O-N 3.1Å; V297-F299 VanDerWaalsContact C-N 3.29Å; V297-F299 PolarHBondContact O-N 2.8Å; V297-A300 CarbonylContact O-C 3.48Å; V297-A300 WeakPolarHBondContact O-CA 3.29Å; V297-A300 WeakPolarHBondContact O-CB 3.2Å; V297-A300 PolarHBondContact O-N 3.05Å; V297-D301 PolarHBondContact O-N 3.49Å; V297-P312 HydrophobicContact CG2-CB 3.76Å; V297-P312 HydrophobicContact CG2-CG 4.29Å
298	T	90.3	Very high	87.7	Confident	26 Å²	26	43.9 Å²	43.9	16%	0.16	25%	0.249	C	C	.	.	H	α-helix	trans	-59.3	-40.3	176.3	-52.6	0	0	0	0	112	L284 S292 A294 V295 A300	L284-T298 HydrophobicContact CD1-CG2 4.41Å; L284-T298 HydrophobicContact CD2-CG2 3.99Å; S292-T298 WeakPolarHBondContact CB-OG1 3.32Å; S292-T298 PolarHBondContact OG-OG1 3.11Å; A294-T298 PolarHBondContact O-N 3.11Å; A294-T298 PolarHBondContact O-OG1 2.87Å; V295-T298 PolarHBondContact O-N 2.69Å; T298-A300 VanDerWaalsContact C-N 3.34Å
299	F	91.6	Very high	87.3	Confident	0 Å²	0	50 Å²	50	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-60.7	-44.5	170.2	176	-93.7	0	0	0	111.5	V197 T200 A279 Y280 V283 L284 V295 V297 D301 Q302 V303 F304	V197-F299 HydrophobicContact CB-CE1 4.26Å; V197-F299 HydrophobicContact CG1-CD1 4.24Å; V197-F299 HydrophobicContact CG1-CE1 3.88Å; V197-F299 HydrophobicContact CG1-CZ 4.17Å; V197-F299 HydrophobicContact CG2-CD1 4.27Å; V197-F299 HydrophobicContact CG2-CE1 4.16Å; T200-F299 HydrophobicContact CG2-CE1 4.19Å; T200-F299 HydrophobicContact CG2-CZ 3.94Å; A279-F299 HydrophobicContact CB-CE2 4.47Å; A279-F299 HydrophobicContact CB-CZ 4.48Å; A279-F299 WeakPolarHBondContact O-CE2 3.22Å; Y280-F299 HydrophobicContact CD1-CB 3.86Å; Y280-F299 AromaticContact CD1-CD2 3.8Å; Y280-F299 HydrophobicContact CD1-CD2 3.8Å; Y280-F299 HydrophobicContact CD1-CE2 4.48Å; Y280-F299 AromaticContact CD1-CG 3.83Å; Y280-F299 HydrophobicContact CD1-CG 3.83Å; Y280-F299 HydrophobicContact CE1-CB 3.96Å; Y280-F299 HydrophobicContact CE1-CD1 4.45Å; Y280-F299 HydrophobicContact CE1-CD2 4.45Å; Y280-F299 HydrophobicContact CE1-CG 4.04Å; V283-F299 HydrophobicContact CB-CD2 3.81Å; V283-F299 HydrophobicContact CB-CE2 3.72Å; V283-F299 HydrophobicContact CG1-CD2 4.09Å; V283-F299 HydrophobicContact CG1-CE2 4.27Å; V283-F299 HydrophobicContact CG2-CD2 4.09Å; V283-F299 HydrophobicContact CG2-CE2 3.46Å; V283-F299 VanDerWaalsContact CG2-CE2 3.46Å; V283-F299 HydrophobicContact CG2-CZ 4.29Å; L284-F299 HydrophobicContact CD1-CB 4.05Å; V295-F299 WeakPolarHBondContact O-CB 3.24Å; V295-F299 PolarHBondContact O-N 3Å; V297-F299 VanDerWaalsContact C-N 3.29Å; V297-F299 PolarHBondContact O-N 2.8Å; F299-D301 PolarHBondContact O-N 2.92Å; F299-Q302 PolarHBondContact O-N 3.38Å; F299-V303 HydrophobicContact CE2-CG2 4.43Å; F299-V303 HydrophobicContact CZ-CG2 4.35Å; F299-V303 PolarHBondContact O-N 3.35Å; F299-F304 HydrophobicContact CD1-CE2 4.37Å; F299-F304 AromaticContact CE1-CE2 3.95Å; F299-F304 HydrophobicContact CE1-CE2 3.95Å
300	A	89.5	Confident	87	Confident	0 Å²	0	52.4 Å²	52.4	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-67.3	-37.6	-176.3	0	0	0	0	0	113.3	A296 V297 T298 Q302 V303 F304 N308 I311	A296-A300 WeakPolarHBondContact O-CB 3.29Å; A296-A300 PolarHBondContact O-N 2.78Å; V297-A300 CarbonylContact O-C 3.48Å; V297-A300 WeakPolarHBondContact O-CA 3.29Å; V297-A300 WeakPolarHBondContact O-CB 3.2Å; V297-A300 PolarHBondContact O-N 3.05Å; T298-A300 VanDerWaalsContact C-N 3.34Å; A300-Q302 PolarHBondContact O-N 2.91Å; A300-V303 PolarHBondContact O-N 3.31Å; A300-F304 HydrophobicContact CB-CD2 3.96Å; A300-F304 PolarHBondContact O-N 3.47Å; A300-N308 HydrophobicContact CB-CB 4.49Å; A300-I311 HydrophobicContact CB-CB 3.86Å; A300-I311 HydrophobicContact CB-CG1 3.67Å; A300-I311 HydrophobicContact CB-CG2 4.27Å
301	D	88.4	Confident	86.7	Confident	71 Å²	71	50.4 Å²	50.4	38%	0.38	27%	0.271	S	S	.	.	H	α-helix	trans	-62	-32.2	176.9	-72.1	-28.7	0	0	0	112.2	V297 F299 N308	V297-D301 PolarHBondContact O-N 3.49Å; F299-D301 PolarHBondContact O-N 2.92Å; D301-N308 WeakPolarHBondContact OD1-CB 3.39Å; D301-N308 PolarHBondContact OD1-ND2 3.25Å
302	Q	87.8	Confident	86.6	Confident	101 Å²	101	44.2 Å²	44.2	47%	0.472	24%	0.238	S	C	.	.	H	α-helix	trans	-80.1	-19.6	178	-66.6	-166.3	11.9	0	0	114.1	V283 L284 F299 A300	V283-Q302 HydrophobicContact CG1-CB 3.84Å; V283-Q302 VanDerWaalsContact CG1-OE1 3.27Å; V283-Q302 PolarHBondContact O-OE1 3.31Å; L284-Q302 VanDerWaalsContact CD2-CD 3.5Å; L284-Q302 HydrophobicContact CD2-CG 4.29Å; F299-Q302 PolarHBondContact O-N 3.38Å; A300-Q302 PolarHBondContact O-N 2.91Å
303	V	88.5	Confident	86.6	Confident	40 Å²	40	47.5 Å²	47.5	24%	0.242	26%	0.255	C	S	.	.	H	α-helix	trans	-126.9	-40.5	-169.6	-162.8	0	0	0	0	115.3	T200 V283 F299 A300	T200-V303 HydrophobicContact CG2-CB 3.92Å; T200-V303 HydrophobicContact CG2-CG1 3.16Å; T200-V303 HydrophobicContact CG2-CG2 4.33Å; V283-V303 HydrophobicContact CB-CG2 4.48Å; V283-V303 HydrophobicContact CG1-CG2 3.71Å; V283-V303 HydrophobicContact CG2-CG2 3.99Å; F299-V303 HydrophobicContact CE2-CG2 4.43Å; F299-V303 HydrophobicContact CZ-CG2 4.35Å; F299-V303 PolarHBondContact O-N 3.35Å; A300-V303 PolarHBondContact O-N 3.31Å
304	F	83	Confident	86.7	Confident	38 Å²	38	44.4 Å²	44.4	17%	0.167	24%	0.241	C	C	.	.	T	Hydrogen-bonded Turn	trans	-87.1	-8.5	-172.5	-74.4	-74.3	0	0	0	113.9	A196 T200 F299 A300 V306 M307 I311	A196-F304 HydrophobicContact CB-CZ 4.28Å; T200-F304 HydrophobicContact CG2-CE2 4.5Å; T200-F304 HydrophobicContact CG2-CZ 4.31Å; T200-F304 VanDerWaalsContact OG1-CZ 3.26Å; T200-F304 WeakPolarHBondContact OG1-CZ 3.25Å; F299-F304 HydrophobicContact CD1-CE2 4.37Å; F299-F304 AromaticContact CE1-CE2 3.95Å; F299-F304 HydrophobicContact CE1-CE2 3.95Å; A300-F304 HydrophobicContact CB-CD2 3.96Å; A300-F304 PolarHBondContact O-N 3.47Å; F304-V306 PolarHBondContact O-N 3.35Å; F304-V306 VanDerWaalsContact O-N 3.1Å; F304-M307 HydrophobicContact CB-CB 4.26Å; F304-M307 PolarHBondContact O-N 3.3Å; F304-I311 HydrophobicContact CD2-CG1 4.34Å; F304-I311 HydrophobicContact CE2-CD1 4.44Å; F304-I311 HydrophobicContact CE2-CG1 4.43Å
305	G	83.7	Confident	86.6	Confident	45 Å²	45	44.5 Å²	44.5	46%	0.464	24%	0.241	S	C	.	.	G	3₁₀ helix	trans	52.3	-116.9	177.2	0	0	0	0	0	111.7	M307 N308	G305-M307 PolarHBondContact O-N 2.88Å; G305-M307 VanDerWaalsContact O-N 3.17Å; G305-N308 VanDerWaalsContact O-CB 3.28Å; G305-N308 WeakPolarHBondContact O-CB 3.28Å; G305-N308 VanDerWaalsContact O-CG 3.23Å; G305-N308 PolarHBondContact O-N 3.01Å; G305-N308 VanDerWaalsContact O-N 3.07Å; G305-N308 PolarHBondContact O-OD1 3.48Å
306	V	80.7	Confident	86.5	Confident	135 Å²	135	44.5 Å²	44.5	82%	0.818	24%	0.242	S	C	*	.	G	3₁₀ helix	trans	-62.3	-22.4	-179.2	-173.5	0	0	0	0	113.3	F304 W309	F304-V306 PolarHBondContact O-N 3.35Å; F304-V306 VanDerWaalsContact O-N 3.1Å; V306-W309 VanDerWaalsContact O-CD1 3.24Å
307	M	79.2	Confident	86.3	Confident	113 Å²	113	47 Å²	47	56%	0.557	25%	0.254	S	S	*	.	G	3₁₀ helix	trans	-91.3	8.1	178	-65.7	-170.2	-67.9	0	0	113.5	F304 G305 W309 T310	F304-M307 HydrophobicContact CB-CB 4.26Å; F304-M307 PolarHBondContact O-N 3.3Å; G305-M307 PolarHBondContact O-N 2.88Å; G305-M307 VanDerWaalsContact O-N 3.17Å; M307-W309 PolarHBondContact O-N 2.88Å; M307-T310 HydrophobicContact CB-CG2 4.45Å; M307-T310 WeakPolarHBondContact O-CB 3.34Å; M307-T310 WeakPolarHBondContact O-CG2 3.3Å; M307-T310 PolarHBondContact O-N 3.15Å; M307-T310 VanDerWaalsContact O-N 3.12Å; M307-T310 PolarHBondContact O-OG1 3.44Å
308	N	81.4	Confident	86.2	Confident	55 Å²	55	47 Å²	47	29%	0.294	25%	0.254	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56	-35	-178.5	66.4	-12.8	0	0	0	113.5	A300 D301 G305 T310 I311 P312	A300-N308 HydrophobicContact CB-CB 4.49Å; D301-N308 WeakPolarHBondContact OD1-CB 3.39Å; D301-N308 PolarHBondContact OD1-ND2 3.25Å; G305-N308 VanDerWaalsContact O-CB 3.28Å; G305-N308 WeakPolarHBondContact O-CB 3.28Å; G305-N308 VanDerWaalsContact O-CG 3.23Å; G305-N308 PolarHBondContact O-N 3.01Å; G305-N308 VanDerWaalsContact O-N 3.07Å; G305-N308 PolarHBondContact O-OD1 3.48Å; N308-T310 PolarHBondContact O-N 3.36Å; N308-T310 VanDerWaalsContact O-N 3.14Å; N308-I311 PolarHBondContact O-N 2.99Å; N308-P312 WeakPolarHBondContact O-CD 3.49Å
309	W	82.8	Confident	86.1	Confident	152 Å²	152	45.7 Å²	45.7	58%	0.576	25%	0.247	S	C	*	.	T	Hydrogen-bonded Turn	trans	-63.1	-18.6	180	69.8	-90.8	0	0	0	114.3	V306 M307 P312 L313	V306-W309 VanDerWaalsContact O-CD1 3.24Å; M307-W309 PolarHBondContact O-N 2.88Å; W309-P312 WeakPolarHBondContact O-CD 3.37Å; W309-P312 WeakPolarHBondContact O-CG 3.42Å; W309-L313 HydrophobicContact CE3-CD2 4.32Å; W309-L313 HydrophobicContact CZ3-CD2 3.83Å
310	T	84.6	Confident	85.9	Confident	50 Å²	50	47.9 Å²	47.9	31%	0.307	26%	0.256	S	S	.	.	H	α-helix	trans	-70	-37.1	-178.5	61.3	0	0	0	0	112.3	M307 N308 A314	M307-T310 HydrophobicContact CB-CG2 4.45Å; M307-T310 WeakPolarHBondContact O-CB 3.34Å; M307-T310 WeakPolarHBondContact O-CG2 3.3Å; M307-T310 PolarHBondContact O-N 3.15Å; M307-T310 VanDerWaalsContact O-N 3.12Å; M307-T310 PolarHBondContact O-OG1 3.44Å; N308-T310 PolarHBondContact O-N 3.36Å; N308-T310 VanDerWaalsContact O-N 3.14Å; T310-A314 WeakPolarHBondContact O-CB 3.39Å; T310-A314 PolarHBondContact O-N 3.11Å
311	I	86.8	Confident	85.6	Confident	8 Å²	8	48.2 Å²	48.2	4%	0.041	26%	0.259	C	S	.	.	H	α-helix	trans	-66.2	-53.5	-179.8	-62.4	-62.2	0	0	0	112.9	V197 A296 A300 F304 N308 L313 A314 V315	V197-I311 HydrophobicContact CG2-CD1 4.3Å; A296-I311 HydrophobicContact CB-CG2 3.83Å; A300-I311 HydrophobicContact CB-CB 3.86Å; A300-I311 HydrophobicContact CB-CG1 3.67Å; A300-I311 HydrophobicContact CB-CG2 4.27Å; F304-I311 HydrophobicContact CD2-CG1 4.34Å; F304-I311 HydrophobicContact CE2-CD1 4.44Å; F304-I311 HydrophobicContact CE2-CG1 4.43Å; N308-I311 PolarHBondContact O-N 2.99Å; I311-L313 PolarHBondContact O-N 2.92Å; I311-A314 PolarHBondContact O-N 3.36Å; I311-A314 VanDerWaalsContact O-N 3.16Å; I311-V315 HydrophobicContact CG2-CG2 4.26Å; I311-V315 WeakPolarHBondContact O-CG2 3.31Å; I311-V315 PolarHBondContact O-N 3.31Å
312	P	88.1	Confident	85.4	Confident	5 Å²	5	45.8 Å²	45.8	3%	0.032	25%	0.251	C	S	.	.	H	α-helix	trans	-58.7	-38.1	177.9	19.6	-28.9	0	0	0	112.1	Y141 P145 V297 N308 W309 A316	Y141-P312 WeakPolarHBondContact O-CB 3.13Å; P145-P312 HydrophobicContact CG-CB 3.64Å; P145-P312 HydrophobicContact CG-CG 3.6Å; V297-P312 HydrophobicContact CG2-CB 3.76Å; V297-P312 HydrophobicContact CG2-CG 4.29Å; N308-P312 WeakPolarHBondContact O-CD 3.49Å; W309-P312 WeakPolarHBondContact O-CD 3.37Å; W309-P312 WeakPolarHBondContact O-CG 3.42Å; P312-A316 WeakPolarHBondContact O-CB 3.5Å; P312-A316 PolarHBondContact O-N 3.2Å
313	L	87.3	Confident	85.4	Confident	74 Å²	74	41 Å²	41	39%	0.387	23%	0.229	S	C	.	.	H	α-helix	trans	-64	-49.2	174.8	-177.2	63.2	0	0	0	111.6	W309 I311 V315 A316 L317	W309-L313 HydrophobicContact CE3-CD2 4.32Å; W309-L313 HydrophobicContact CZ3-CD2 3.83Å; I311-L313 PolarHBondContact O-N 2.92Å; L313-V315 VanDerWaalsContact C-N 3.32Å; L313-V315 PolarHBondContact O-N 3.26Å; L313-A316 PolarHBondContact O-N 3.42Å; L313-L317 HydrophobicContact CD1-CD1 4.3Å; L313-L317 HydrophobicContact CD1-CG 4.29Å; L313-L317 HydrophobicContact CG-CD1 4.15Å; L313-L317 WeakPolarHBondContact O-CB 3.42Å; L313-L317 VanDerWaalsContact O-CG 3.24Å; L313-L317 WeakPolarHBondContact O-CG 3.39Å; L313-L317 PolarHBondContact O-N 2.93Å
314	A	86.7	Confident	85.3	Confident	17 Å²	17	39.3 Å²	39.3	14%	0.14	22%	0.219	C	C	.	.	H	α-helix	trans	-60.8	-40.9	179.1	0	0	0	0	0	112.3	A193 T310 I311 S318	A193-A314 HydrophobicContact CB-CB 3.74Å; T310-A314 WeakPolarHBondContact O-CB 3.39Å; T310-A314 PolarHBondContact O-N 3.11Å; I311-A314 PolarHBondContact O-N 3.36Å; I311-A314 VanDerWaalsContact O-N 3.16Å; A314-S318 WeakPolarHBondContact O-CB 3.22Å; A314-S318 PolarHBondContact O-N 3.49Å
315	V	87.6	Confident	85.2	Confident	1 Å²	1	38.2 Å²	38.2	1%	0.006	22%	0.217	C	C	.	.	H	α-helix	trans	-69	-42.2	177.2	178.1	0	0	0	0	111.5	F55 Y141 I311 L313 L317 S318 C319	F55-V315 HydrophobicContact CB-CG1 4.06Å; F55-V315 HydrophobicContact CD1-CG1 4.19Å; F55-V315 HydrophobicContact CD1-CG2 3.74Å; F55-V315 HydrophobicContact CD2-CB 4.42Å; F55-V315 HydrophobicContact CD2-CG1 3.56Å; F55-V315 HydrophobicContact CD2-CG2 4.14Å; F55-V315 HydrophobicContact CE1-CG2 3.52Å; F55-V315 HydrophobicContact CE2-CB 4.44Å; F55-V315 HydrophobicContact CE2-CG1 4.03Å; F55-V315 HydrophobicContact CE2-CG2 3.93Å; F55-V315 HydrophobicContact CG-CG1 3.65Å; F55-V315 HydrophobicContact CG-CG2 4.05Å; F55-V315 HydrophobicContact CZ-CG2 3.62Å; Y141-V315 HydrophobicContact CD1-CB 3.51Å; Y141-V315 HydrophobicContact CD1-CG1 3.4Å; Y141-V315 VanDerWaalsContact CD1-CG1 3.4Å; Y141-V315 HydrophobicContact CD1-CG2 3.96Å; Y141-V315 HydrophobicContact CD2-CG1 3.88Å; Y141-V315 HydrophobicContact CE1-CB 3.83Å; Y141-V315 HydrophobicContact CE1-CG1 3.58Å; Y141-V315 HydrophobicContact CE1-CG2 3.8Å; Y141-V315 HydrophobicContact CE2-CG1 4.04Å; Y141-V315 HydrophobicContact CG-CB 4.05Å; Y141-V315 HydrophobicContact CG-CG1 3.55Å; I311-V315 HydrophobicContact CG2-CG2 4.26Å; I311-V315 WeakPolarHBondContact O-CG2 3.31Å; I311-V315 PolarHBondContact O-N 3.31Å; L313-V315 VanDerWaalsContact C-N 3.32Å; L313-V315 PolarHBondContact O-N 3.26Å; V315-L317 PolarHBondContact O-N 2.83Å; V315-S318 VanDerWaalsContact O-CB 3.28Å; V315-S318 WeakPolarHBondContact O-CB 3.04Å; V315-S318 PolarHBondContact O-N 3.49Å; V315-C319 PolarHBondContact O-N 3.44Å; V315-C319 PolarHBondContact O-SG 2.69Å
316	A	89.3	Confident	85.2	Confident	2 Å²	2	36.9 Å²	36.9	2%	0.017	20%	0.2	C	C	.	.	H	α-helix	trans	-61.7	-44.4	176.4	0	0	0	0	0	111.4	F138 M142 P312 L313 S318 C319 F320	F138-A316 HydrophobicContact CD2-CB 3.84Å; F138-A316 WeakPolarHBondContact CD2-O 3.49Å; F138-A316 HydrophobicContact CE2-CB 3.89Å; M142-A316 HydrophobicContact CE-CB 3.43Å; M142-A316 VanDerWaalsContact CE-CB 3.43Å; M142-A316 HydrophobicContact CG-CB 3.73Å; M142-A316 HydrophobicContact SD-CB 3.58Å; M142-A316 VanDerWaalsContact SD-CB 3.58Å; P312-A316 WeakPolarHBondContact O-CB 3.5Å; P312-A316 PolarHBondContact O-N 3.2Å; L313-A316 PolarHBondContact O-N 3.42Å; A316-S318 VanDerWaalsContact C-N 3.3Å; A316-S318 PolarHBondContact O-N 3.41Å; A316-C319 PolarHBondContact O-N 2.81Å; A316-F320 WeakPolarHBondContact O-CB 3.36Å; A316-F320 PolarHBondContact O-N 3.41Å
317	L	86	Confident	85.6	Confident	52 Å²	52	30.4 Å²	30.4	27%	0.272	16%	0.161	S	C	.	.	H	α-helix	trans	-62.3	-37.1	174.5	-66.4	177.2	0	0	0	112.1	F186 L313 V315 F320 G321	F186-L317 HydrophobicContact CD1-CB 3.76Å; F186-L317 HydrophobicContact CD1-CD1 4.16Å; F186-L317 HydrophobicContact CD1-CD2 4.31Å; F186-L317 HydrophobicContact CD1-CG 4.28Å; F186-L317 HydrophobicContact CE1-CB 3.96Å; F186-L317 HydrophobicContact CE1-CD1 3.87Å; F186-L317 HydrophobicContact CE1-CD2 3.61Å; F186-L317 HydrophobicContact CE1-CG 4Å; F186-L317 HydrophobicContact CE2-CD2 4.44Å; F186-L317 HydrophobicContact CG-CB 4.2Å; F186-L317 HydrophobicContact CZ-CD2 3.69Å; L313-L317 HydrophobicContact CD1-CD1 4.3Å; L313-L317 HydrophobicContact CD1-CG 4.29Å; L313-L317 HydrophobicContact CG-CD1 4.15Å; L313-L317 WeakPolarHBondContact O-CB 3.42Å; L313-L317 VanDerWaalsContact O-CG 3.24Å; L313-L317 WeakPolarHBondContact O-CG 3.39Å; L313-L317 PolarHBondContact O-N 2.93Å; V315-L317 PolarHBondContact O-N 2.83Å; L317-F320 PolarHBondContact O-N 2.91Å; L317-G321 PolarHBondContact O-N 3.49Å
318	S	86.5	Confident	85.7	Confident	1 Å²	1	26.1 Å²	26.1	1%	0.007	14%	0.141	C	C	.	.	H	α-helix	trans	-60.7	-48.2	172.6	-178.1	0	0	0	0	112	K190 A314 V315 A316 F320 G321 G322	K190-S318 WeakPolarHBondContact CD-OG 3.34Å; A314-S318 WeakPolarHBondContact O-CB 3.22Å; A314-S318 PolarHBondContact O-N 3.49Å; V315-S318 VanDerWaalsContact O-CB 3.28Å; V315-S318 WeakPolarHBondContact O-CB 3.04Å; V315-S318 PolarHBondContact O-N 3.49Å; A316-S318 VanDerWaalsContact C-N 3.3Å; A316-S318 PolarHBondContact O-N 3.41Å; S318-F320 VanDerWaalsContact C-N 3.34Å; S318-F320 PolarHBondContact O-N 3.22Å; S318-G321 PolarHBondContact O-N 2.9Å; S318-G322 PolarHBondContact O-N 3.33Å
319	C	88.9	Confident	85.6	Confident	0 Å²	0	25.7 Å²	25.7	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-64.3	-40.2	178.5	-61.7	0	0	0	0	111.3	S52 I134 F138 V315 A316 G322 L323	S52-C319 VanDerWaalsContact CB-SG 3.52Å; I134-C319 HydrophobicContact CG2-CB 3.98Å; I134-C319 WeakPolarHBondContact CG2-O 3.24Å; F138-C319 HydrophobicContact CB-CB 3.66Å; F138-C319 HydrophobicContact CD2-CB 4.47Å; V315-C319 PolarHBondContact O-N 3.44Å; V315-C319 PolarHBondContact O-SG 2.69Å; A316-C319 PolarHBondContact O-N 2.81Å; C319-G322 PolarHBondContact O-N 2.83Å; C319-L323 VanDerWaalsContact O-CB 3.26Å; C319-L323 WeakPolarHBondContact O-CB 3.4Å; C319-L323 PolarHBondContact O-N 3.42Å
320	F	87.9	Confident	85.7	Confident	45 Å²	45	18.4 Å²	18.4	20%	0.197	12%	0.117	C	C	.	.	H	α-helix	trans	-60.6	-45.7	175.8	-170.2	-88	0	0	0	111.7	L167 L168 F186 A316 L317 S318 N324	L167-F320 HydrophobicContact CD2-CE2 4.27Å; L168-F320 HydrophobicContact CD1-CD2 4.1Å; L168-F320 HydrophobicContact CD1-CE2 4.12Å; L168-F320 HydrophobicContact CD1-CG 4.36Å; L168-F320 HydrophobicContact CD1-CZ 4.41Å; L168-F320 HydrophobicContact CD2-CD1 4.1Å; L168-F320 HydrophobicContact CD2-CD2 4.39Å; L168-F320 HydrophobicContact CD2-CE1 3.46Å; L168-F320 VanDerWaalsContact CD2-CE1 3.46Å; L168-F320 HydrophobicContact CD2-CE2 3.78Å; L168-F320 HydrophobicContact CD2-CZ 3.27Å; L168-F320 HydrophobicContact CG-CD2 4.31Å; L168-F320 HydrophobicContact CG-CE1 4.36Å; L168-F320 HydrophobicContact CG-CE2 3.82Å; L168-F320 HydrophobicContact CG-CZ 3.86Å; F186-F320 AromaticContact CE2-CD1 3.93Å; F186-F320 HydrophobicContact CE2-CD1 3.93Å; A316-F320 WeakPolarHBondContact O-CB 3.36Å; A316-F320 PolarHBondContact O-N 3.41Å; L317-F320 PolarHBondContact O-N 2.91Å; S318-F320 VanDerWaalsContact C-N 3.34Å; S318-F320 PolarHBondContact O-N 3.22Å; F320-N324 WeakPolarHBondContact O-CB 3.16Å; F320-N324 PolarHBondContact O-N 3.35Å
321	G	82.8	Confident	85.5	Confident	7 Å²	7	16.5 Å²	16.5	7%	0.072	11%	0.106	C	C	.	.	H	α-helix	trans	-63.8	-44	175	0	0	0	0	0	113.1	L317 S318 N324 A325	L317-G321 PolarHBondContact O-N 3.49Å; S318-G321 PolarHBondContact O-N 2.9Å; G321-N324 PolarHBondContact O-N 2.94Å; G321-A325 PolarHBondContact O-N 3.25Å
322	G	83.2	Confident	85.1	Confident	20 Å²	20	22.1 Å²	22.1	21%	0.206	13%	0.127	C	C	.	.	H	α-helix	trans	-64.5	-40.6	177.7	0	0	0	0	0	112.9	S318 C319 A325 S326	S318-G322 PolarHBondContact O-N 3.33Å; C319-G322 PolarHBondContact O-N 2.83Å; G322-A325 PolarHBondContact O-N 3.46Å; G322-S326 PolarHBondContact O-N 3.44Å
323	L	88.8	Confident	84.8	Confident	0 Å²	0	22.1 Å²	22.1	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-64.2	-43.4	176.3	-177.9	54.2	0	0	0	111	Q131 I134 A135 I165 L168 C319 A325 S326 I327	Q131-L323 HydrophobicContact CB-CD1 3.62Å; Q131-L323 HydrophobicContact CG-CD1 3.84Å; I134-L323 HydrophobicContact CG2-CB 3.81Å; A135-L323 HydrophobicContact CB-CD2 3.97Å; I165-L323 HydrophobicContact CG1-CD2 3.99Å; L168-L323 HydrophobicContact CD1-CB 3.75Å; L168-L323 HydrophobicContact CD1-CD2 3.66Å; L168-L323 HydrophobicContact CD1-CG 3.58Å; C319-L323 VanDerWaalsContact O-CB 3.26Å; C319-L323 WeakPolarHBondContact O-CB 3.4Å; C319-L323 PolarHBondContact O-N 3.42Å; L323-A325 PolarHBondContact O-N 3Å; L323-S326 PolarHBondContact O-N 2.92Å; L323-I327 HydrophobicContact CD1-CD1 4.09Å; L323-I327 HydrophobicContact CD1-CG1 4.34Å; L323-I327 HydrophobicContact CG-CD1 4.03Å; L323-I327 VanDerWaalsContact O-CG1 3.29Å; L323-I327 WeakPolarHBondContact O-CG1 3.29Å; L323-I327 PolarHBondContact O-N 3.42Å
324	N	85.9	Confident	84.5	Confident	6 Å²	6	18.6 Å²	18.6	3%	0.032	11%	0.108	C	C	.	.	H	α-helix	trans	-60.2	-45.5	174.9	-175.4	73.4	0	0	0	112	L168 N172 G179 F320 G321 S326 I327 V328	L168-N324 HydrophobicContact CD1-CB 4.36Å; L168-N324 HydrophobicContact CD2-CB 3.98Å; N172-N324 PolarHBondContact ND2-OD1 3.11Å; N172-N324 PolarHBondContact OD1-OD1 3.37Å; G179-N324 PolarHBondContact O-ND2 2.57Å; F320-N324 WeakPolarHBondContact O-CB 3.16Å; F320-N324 PolarHBondContact O-N 3.35Å; G321-N324 PolarHBondContact O-N 2.94Å; N324-S326 PolarHBondContact O-N 3.44Å; N324-I327 PolarHBondContact O-N 2.86Å; N324-V328 WeakPolarHBondContact O-CG2 3.38Å; N324-V328 PolarHBondContact O-N 3.21Å; N324-V328 VanDerWaalsContact O-N 3.09Å
325	A	80.2	Confident	83.9	Confident	15 Å²	15	20.1 Å²	20.1	12%	0.124	11%	0.112	C	C	.	.	H	α-helix	trans	-60.4	-44.4	178.1	0	0	0	0	0	111.9	G321 G322 L323 V328 A329	G321-A325 PolarHBondContact O-N 3.25Å; G322-A325 PolarHBondContact O-N 3.46Å; L323-A325 PolarHBondContact O-N 3Å; A325-V328 PolarHBondContact O-N 3.46Å; A325-A329 WeakPolarHBondContact O-CB 3.3Å; A325-A329 PolarHBondContact O-N 3.22Å
326	S	85.6	Confident	83.4	Confident	16 Å²	16	21.6 Å²	21.6	11%	0.112	12%	0.121	C	C	.	.	H	α-helix	trans	-64.6	-43.1	178	178.1	0	0	0	0	112.3	Q131 G322 L323 N324 V328 A329 A330	Q131-S326 WeakPolarHBondContact CG-OG 3.44Å; Q131-S326 PolarHBondContact NE2-OG 3.26Å; G322-S326 PolarHBondContact O-N 3.44Å; L323-S326 PolarHBondContact O-N 2.92Å; N324-S326 PolarHBondContact O-N 3.44Å; S326-V328 VanDerWaalsContact C-N 3.32Å; S326-V328 PolarHBondContact O-N 2.96Å; S326-A329 PolarHBondContact O-N 3.23Å; S326-A330 WeakPolarHBondContact O-CB 3.41Å; S326-A330 PolarHBondContact O-N 3.28Å
327	I	87.6	Confident	83	Confident	0 Å²	0	21.5 Å²	21.5	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-59.8	-43.6	177	-71.4	167.3	0	0	0	111	Q131 L168 N172 L323 N324 S331 L361	Q131-I327 HydrophobicContact CG-CG1 4.49Å; L168-I327 HydrophobicContact CB-CD1 3.82Å; N172-I327 HydrophobicContact CB-CG2 4.45Å; L323-I327 HydrophobicContact CD1-CD1 4.09Å; L323-I327 HydrophobicContact CD1-CG1 4.34Å; L323-I327 HydrophobicContact CG-CD1 4.03Å; L323-I327 VanDerWaalsContact O-CG1 3.29Å; L323-I327 WeakPolarHBondContact O-CG1 3.29Å; L323-I327 PolarHBondContact O-N 3.42Å; N324-I327 PolarHBondContact O-N 2.86Å; I327-S331 PolarHBondContact O-N 3.27Å; I327-L361 HydrophobicContact CG2-CD2 3.46Å; I327-L361 VanDerWaalsContact CG2-CD2 3.46Å
328	V	81.1	Confident	82.7	Confident	23 Å²	23	19.2 Å²	19.2	14%	0.139	11%	0.108	C	C	.	.	H	α-helix	trans	-66	-44.8	177	173.8	0	0	0	0	110.9	N172 N324 A325 S326 S331 R332	N172-V328 WeakPolarHBondContact OD1-CG2 3.35Å; N324-V328 WeakPolarHBondContact O-CG2 3.38Å; N324-V328 PolarHBondContact O-N 3.21Å; N324-V328 VanDerWaalsContact O-N 3.09Å; A325-V328 PolarHBondContact O-N 3.46Å; S326-V328 VanDerWaalsContact C-N 3.32Å; S326-V328 PolarHBondContact O-N 2.96Å; V328-S331 PolarHBondContact O-N 3.32Å; V328-S331 PolarHBondContact O-OG 2.96Å; V328-R332 PolarHBondContact O-N 3.39Å
329	A	79.8	Confident	82.2	Confident	45 Å²	45	24.4 Å²	24.4	37%	0.372	13%	0.127	S	C	.	.	H	α-helix	trans	-61.1	-46.4	179.3	0	0	0	0	0	112.3	A325 S326 S331 R332 L333	A325-A329 WeakPolarHBondContact O-CB 3.3Å; A325-A329 PolarHBondContact O-N 3.22Å; S326-A329 PolarHBondContact O-N 3.23Å; A329-S331 VanDerWaalsContact C-N 3.3Å; A329-S331 PolarHBondContact O-N 2.91Å; A329-R332 PolarHBondContact O-N 3.41Å; A329-R332 VanDerWaalsContact O-N 3.14Å; A329-L333 PolarHBondContact O-N 3.41Å; A329-L333 VanDerWaalsContact O-N 3.14Å
330	A	84.6	Confident	81.9	Confident	0 Å²	0	28.3 Å²	28.3	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-57.8	-42.8	177	0	0	0	0	0	111.6	E127 S326 R332 L333 F334	E127-A330 HydrophobicContact CB-CB 3.94Å; E127-A330 HydrophobicContact CG-CB 3.86Å; S326-A330 WeakPolarHBondContact O-CB 3.41Å; S326-A330 PolarHBondContact O-N 3.28Å; A330-R332 VanDerWaalsContact C-N 3.3Å; A330-R332 PolarHBondContact O-N 3.13Å; A330-L333 WeakPolarHBondContact O-CB 3.42Å; A330-L333 PolarHBondContact O-N 3.24Å; A330-F334 HydrophobicContact CB-CE1 4.33Å; A330-F334 HydrophobicContact CB-CZ 4.13Å; A330-F334 WeakPolarHBondContact O-CD1 3.12Å; A330-F334 WeakPolarHBondContact O-CE1 3.36Å; A330-F334 VanDerWaalsContact O-CG 3.27Å; A330-F334 WeakPolarHBondContact O-CG 3.39Å; A330-F334 PolarHBondContact O-N 3.26Å; A330-F334 VanDerWaalsContact O-N 3.12Å
331	S	81.8	Confident	81.5	Confident	10 Å²	10	28.2 Å²	28.2	7%	0.07	16%	0.158	C	C	.	.	H	α-helix	trans	-61.1	-36.3	178.4	76	0	0	0	0	113.4	I327 V328 A329 F334 F335	I327-S331 PolarHBondContact O-N 3.27Å; V328-S331 PolarHBondContact O-N 3.32Å; V328-S331 PolarHBondContact O-OG 2.96Å; A329-S331 VanDerWaalsContact C-N 3.3Å; A329-S331 PolarHBondContact O-N 2.91Å; S331-F334 PolarHBondContact O-N 3.44Å; S331-F335 PolarHBondContact O-N 3.33Å; S331-F335 VanDerWaalsContact O-N 3.17Å
332	R	77.3	Confident	81.6	Confident	125 Å²	125	29 Å²	29	47%	0.472	16%	0.16	S	C	.	.	H	α-helix	trans	-69.1	-41.1	176.1	-67.5	-179.4	-179.7	-160.5	-1.8	111.8	E250 V328 A329 A330 F334 F335 V336	E250-R332 IonicContact OE1-NH1 3.85Å; V328-R332 PolarHBondContact O-N 3.39Å; A329-R332 PolarHBondContact O-N 3.41Å; A329-R332 VanDerWaalsContact O-N 3.14Å; A330-R332 VanDerWaalsContact C-N 3.3Å; A330-R332 PolarHBondContact O-N 3.13Å; R332-F334 PolarHBondContact O-N 2.53Å; R332-F335 WeakPolarHBondContact O-CB 3.37Å; R332-F335 PolarHBondContact O-N 2.99Å; R332-V336 WeakPolarHBondContact O-CG2 3.17Å; R332-V336 PolarHBondContact O-N 3.32Å
333	L	81.3	Confident	81.6	Confident	6 Å²	6	28.6 Å²	28.6	3%	0.031	15%	0.152	C	C	.	.	H	α-helix	trans	-59.1	-39.8	176.4	-179.7	62.3	0	0	0	111.1	L119 A329 A330 V336 G337	L119-L333 HydrophobicContact CD1-CD1 3.97Å; L119-L333 HydrophobicContact CD1-CD2 4.33Å; L119-L333 HydrophobicContact CD1-CG 3.8Å; A329-L333 PolarHBondContact O-N 3.41Å; A329-L333 VanDerWaalsContact O-N 3.14Å; A330-L333 WeakPolarHBondContact O-CB 3.42Å; A330-L333 PolarHBondContact O-N 3.24Å; L333-V336 PolarHBondContact O-N 3.46Å; L333-G337 PolarHBondContact O-N 3.11Å
334	F	81.6	Confident	81.3	Confident	0 Å²	0	30.8 Å²	30.8	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-70.6	-37.5	-179	-58	-1.2	0	0	0	111.3	L123 A330 S331 R332 G337 S338 L343 A360 F363 N364	L123-F334 HydrophobicContact CB-CE1 4.48Å; L123-F334 HydrophobicContact CD2-CD1 3.29Å; L123-F334 HydrophobicContact CD2-CD2 3.83Å; L123-F334 HydrophobicContact CD2-CE1 3.13Å; L123-F334 HydrophobicContact CD2-CE2 3.64Å; L123-F334 HydrophobicContact CD2-CG 3.7Å; L123-F334 HydrophobicContact CD2-CZ 3.34Å; L123-F334 HydrophobicContact CG-CD1 3.93Å; L123-F334 HydrophobicContact CG-CE1 3.67Å; L123-F334 HydrophobicContact CG-CZ 4.22Å; A330-F334 HydrophobicContact CB-CE1 4.33Å; A330-F334 HydrophobicContact CB-CZ 4.13Å; A330-F334 WeakPolarHBondContact O-CD1 3.12Å; A330-F334 WeakPolarHBondContact O-CE1 3.36Å; A330-F334 VanDerWaalsContact O-CG 3.27Å; A330-F334 WeakPolarHBondContact O-CG 3.39Å; A330-F334 PolarHBondContact O-N 3.26Å; A330-F334 VanDerWaalsContact O-N 3.12Å; S331-F334 PolarHBondContact O-N 3.44Å; R332-F334 PolarHBondContact O-N 2.53Å; F334-G337 PolarHBondContact O-N 2.98Å; F334-S338 PolarHBondContact O-N 2.98Å; F334-L343 HydrophobicContact CB-CD1 4.42Å; F334-A360 HydrophobicContact CB-CB 4.18Å; F334-A360 HydrophobicContact CD2-CB 3.74Å; F334-A360 HydrophobicContact CG-CB 4.46Å; F334-F363 AromaticContact CE2-CD1 3.97Å; F334-F363 HydrophobicContact CE2-CD1 3.97Å; F334-N364 HydrophobicContact CE2-CB 3.81Å; F334-N364 HydrophobicContact CZ-CB 4.18Å
335	F	75.1	Confident	81	Confident	49 Å²	49	34.6 Å²	34.6	22%	0.215	19%	0.187	C	C	.	.	H	α-helix	trans	-59.9	-48.9	173.5	-173.1	-99.5	0	0	0	111.6	S331 R332 S338 R339 C348 I350 T491	S331-F335 PolarHBondContact O-N 3.33Å; S331-F335 VanDerWaalsContact O-N 3.17Å; R332-F335 WeakPolarHBondContact O-CB 3.37Å; R332-F335 PolarHBondContact O-N 2.99Å; F335-S338 PolarHBondContact O-N 2.93Å; F335-R339 VanDerWaalsContact CE1-CD 3.48Å; F335-R339 HydrophobicContact CE1-CG 4.25Å; F335-R339 WeakPolarHBondContact O-CG 3.46Å; F335-R339 PolarHBondContact O-N 3.03Å; F335-R339 VanDerWaalsContact O-N 3.09Å; F335-C348 HydrophobicContact CD2-CB 3.81Å; F335-C348 HydrophobicContact CE2-CB 4.31Å; F335-I350 HydrophobicContact CE2-CD1 3.95Å; F335-I350 HydrophobicContact CE2-CG1 4.33Å; F335-T491 HydrophobicContact CE2-CG2 4.13Å; F335-T491 HydrophobicContact CZ-CG2 4.2Å
336	V	76.5	Confident	81	Confident	32 Å²	32	35.6 Å²	35.6	19%	0.194	19%	0.189	C	C	.	.	H	α-helix	trans	-63.1	-43.8	177.3	174.6	0	0	0	0	111.6	Y103 R332 L333 S338 R339 E340	Y103-V336 HydrophobicContact CD1-CG1 4.16Å; Y103-V336 HydrophobicContact CE1-CG1 4.03Å; R332-V336 WeakPolarHBondContact O-CG2 3.17Å; R332-V336 PolarHBondContact O-N 3.32Å; L333-V336 PolarHBondContact O-N 3.46Å; V336-S338 VanDerWaalsContact C-N 3.29Å; V336-S338 PolarHBondContact O-N 3.47Å; V336-R339 PolarHBondContact O-N 2.91Å; V336-E340 PolarHBondContact O-N 3.46Å
337	G	80.9	Confident	80.7	Confident	0 Å²	0	35.6 Å²	35.6	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-60.7	-36.4	178.7	0	0	0	0	0	113.7	L333 F334 H342 L343	L333-G337 PolarHBondContact O-N 3.11Å; F334-G337 PolarHBondContact O-N 2.98Å; G337-H342 WeakPolarHBondContact O-CB 3.35Å; G337-H342 PolarHBondContact O-N 3.26Å; G337-H342 VanDerWaalsContact O-N 3.11Å; G337-L343 PolarHBondContact O-N 3.17Å
338	S	79.5	Confident	80.3	Confident	4 Å²	4	36 Å²	36	3%	0.028	19%	0.19	C	C	.	.	H	α-helix	trans	-74.1	-37.3	175.5	-167.5	0	0	0	0	112.9	F334 F335 V336 E340 G341 L343 C348	F334-S338 PolarHBondContact O-N 2.98Å; F335-S338 PolarHBondContact O-N 2.93Å; V336-S338 VanDerWaalsContact C-N 3.29Å; V336-S338 PolarHBondContact O-N 3.47Å; S338-E340 PolarHBondContact O-N 2.71Å; S338-G341 WeakPolarHBondContact O-CA 3.46Å; S338-G341 PolarHBondContact O-N 3.11Å; S338-L343 PolarHBondContact OG-O 3.03Å; S338-C348 VanDerWaalsContact CB-CB 3.44Å; S338-C348 PolarHBondContact OG-SG 3.14Å
339	R	76.4	Confident	80.4	Confident	109 Å²	109	35.4 Å²	35.4	41%	0.411	19%	0.186	S	C	.	.	H	α-helix	trans	-59.9	-32.8	176.6	-75.7	-176.3	67.1	170.7	8.6	112.8	F335 V336 G341 D494	F335-R339 VanDerWaalsContact CE1-CD 3.48Å; F335-R339 HydrophobicContact CE1-CG 4.25Å; F335-R339 WeakPolarHBondContact O-CG 3.46Å; F335-R339 PolarHBondContact O-N 3.03Å; F335-R339 VanDerWaalsContact O-N 3.09Å; V336-R339 PolarHBondContact O-N 2.91Å; R339-G341 PolarHBondContact O-N 3.48Å; R339-D494 IonicContact CZ-OD2 3.34Å; R339-D494 IonicContact NH2-OD2 3.59Å; R339-D494 PolarHBondContact NH2-OD2 2.83Å
340	E	81.6	Confident	80.7	Confident	82 Å²	82	34.9 Å²	34.9	38%	0.383	18%	0.177	S	C	.	.	T	Hydrogen-bonded Turn	trans	-81.8	5.4	174.6	-66.9	-66.1	156.2	0	0	113.1	Y103 L107 V336 S338 H342	Y103-E340 HydrophobicContact CE1-CG 4.15Å; Y103-E340 WeakPolarHBondContact OH-CB 3.47Å; L107-E340 HydrophobicContact CD2-CG 4.26Å; V336-E340 PolarHBondContact O-N 3.46Å; S338-E340 PolarHBondContact O-N 2.71Å; E340-H342 PolarHBondContact O-N 3.07Å
341	G	80.9	Confident	80.7	Confident	44 Å²	44	36 Å²	36	45%	0.454	18%	0.182	S	C	.	.	T	Hydrogen-bonded Turn	trans	73	10.7	178.5	0	0	0	0	0	114.8	S338 R339	S338-G341 WeakPolarHBondContact O-CA 3.46Å; S338-G341 PolarHBondContact O-N 3.11Å; R339-G341 PolarHBondContact O-N 3.48Å
342	H	84.3	Confident	80.9	Confident	23 Å²	23	37.9 Å²	37.9	11%	0.106	19%	0.193	C	C	.	.	S	Bend	trans	-87	-17.5	-179.7	-74	164.9	0	0	0	113.5	Y103 G112 F116 L119 G337 E340 C460	Y103-H342 AromaticContact CE2-ND1 3.75Å; Y103-H342 AromaticContact CZ-ND1 3.7Å; Y103-H342 PolarHBondContact OH-CE1 3.33Å; Y103-H342 PolarHBondContact OH-ND1 3.13Å; G112-H342 PolarHBondContact O-CE1 3.26Å; F116-H342 HydrophobicContact CD2-CB 3.99Å; F116-H342 WeakPolarHBondContact CD2-O 3.44Å; F116-H342 WeakPolarHBondContact CE2-O 3.44Å; L119-H342 HydrophobicContact CD2-CB 3.94Å; G337-H342 WeakPolarHBondContact O-CB 3.35Å; G337-H342 PolarHBondContact O-N 3.26Å; G337-H342 VanDerWaalsContact O-N 3.11Å; E340-H342 PolarHBondContact O-N 3.07Å; H342-C460 PolarHBondContact O-SG 3.29Å
343	L	83.8	Confident	81.1	Confident	11 Å²	11	38.4 Å²	38.4	6%	0.058	20%	0.2	C	C	.	.	S	Bend	trans	-121.8	154.7	174.3	-66.5	170.3	0	0	0	111.2	L119 L123 F334 G337 S338 D345	L119-L343 HydrophobicContact CD1-CD1 4.32Å; L119-L343 HydrophobicContact CD2-CD1 3.8Å; L119-L343 HydrophobicContact CD2-CD2 4.26Å; L119-L343 HydrophobicContact CD2-CG 3.73Å; L119-L343 HydrophobicContact CG-CD1 4.19Å; L119-L343 HydrophobicContact CG-CG 4.42Å; L123-L343 HydrophobicContact CD1-CD1 3.89Å; L123-L343 HydrophobicContact CD1-CD2 3.42Å; L123-L343 VanDerWaalsContact CD1-CD2 3.42Å; L123-L343 HydrophobicContact CD1-CG 4.24Å; F334-L343 HydrophobicContact CB-CD1 4.42Å; G337-L343 PolarHBondContact O-N 3.17Å; S338-L343 PolarHBondContact OG-O 3.03Å; L343-D345 PolarHBondContact O-N 3.43Å
344	P	81.3	Confident	81	Confident	46 Å²	46	43.8 Å²	43.8	30%	0.299	22%	0.22	S	C	.	.			trans	-59.4	135.5	173.1	-21.2	32.3	0	0	0	112.1	F346 L347	P344-F346 HydrophobicContact CB-CD1 3.66Å; P344-F346 HydrophobicContact CB-CE1 3.24Å; P344-F346 HydrophobicContact CB-CE2 4.23Å; P344-F346 HydrophobicContact CB-CG 4.32Å; P344-F346 HydrophobicContact CB-CZ 3.56Å; P344-F346 HydrophobicContact CG-CE1 3.99Å; P344-F346 HydrophobicContact CG-CZ 3.92Å; P344-F346 PolarHBondContact O-N 3.36Å; P344-L347 PolarHBondContact O-N 3.44Å
345	D	79.3	Confident	81	Confident	87 Å²	87	52.7 Å²	52.7	47%	0.465	26%	0.255	S	S	.	.	G	3₁₀ helix	trans	-57.5	-22.9	-175	-51.7	-28.2	0	0	0	114.2	L343 L347 C348 L490	L343-D345 PolarHBondContact O-N 3.43Å; D345-L347 PolarHBondContact O-N 2.94Å; D345-C348 PolarHBondContact O-N 3.43Å; D345-C348 PolarHBondContact O-SG 3.21Å; D345-L490 HydrophobicContact CB-CD1 3.86Å; D345-L490 HydrophobicContact CB-CD2 4.13Å; D345-L490 HydrophobicContact CB-CG 4.45Å
346	F	80.1	Confident	81.3	Confident	35 Å²	35	50.4 Å²	50.4	15%	0.154	25%	0.245	C	C	.	.	G	3₁₀ helix	trans	-69.3	-20.4	177.4	61.9	-106.7	0	0	0	113.8	P344 M349 P359 I475 I482	P344-F346 HydrophobicContact CB-CD1 3.66Å; P344-F346 HydrophobicContact CB-CE1 3.24Å; P344-F346 HydrophobicContact CB-CE2 4.23Å; P344-F346 HydrophobicContact CB-CG 4.32Å; P344-F346 HydrophobicContact CB-CZ 3.56Å; P344-F346 HydrophobicContact CG-CE1 3.99Å; P344-F346 HydrophobicContact CG-CZ 3.92Å; P344-F346 PolarHBondContact O-N 3.36Å; F346-M349 HydrophobicContact CB-CE 3.93Å; F346-M349 HydrophobicContact CB-SD 4.14Å; F346-P359 VanDerWaalsContact O-CB 3.3Å; F346-P359 WeakPolarHBondContact O-CB 3.24Å; F346-I475 HydrophobicContact CE1-CG2 4.33Å; F346-I482 HydrophobicContact CB-CD1 4.21Å; F346-I482 HydrophobicContact CB-CG2 4.49Å; F346-I482 HydrophobicContact CD2-CD1 3.36Å; F346-I482 HydrophobicContact CE2-CD1 3.81Å; F346-I482 HydrophobicContact CG-CD1 3.84Å
347	L	80.6	Confident	81.8	Confident	17 Å²	17	49.9 Å²	49.9	9%	0.089	24%	0.242	C	C	.	.	G	3₁₀ helix	trans	-77.1	-22.4	177	-70.1	177.3	0	0	0	112.5	P344 D345 A360 F363	P344-L347 PolarHBondContact O-N 3.44Å; D345-L347 PolarHBondContact O-N 2.94Å; L347-A360 WeakPolarHBondContact O-CB 3.44Å; L347-F363 HydrophobicContact CD2-CB 4.16Å; L347-F363 HydrophobicContact CD2-CG 4.37Å
348	C	78.4	Confident	82.2	Confident	7 Å²	7	50.8 Å²	50.8	5%	0.047	25%	0.247	C	C	.	.	S	Bend	trans	-97.1	3.2	177.7	70.7	0	0	0	0	114.2	F335 S338 D345	F335-C348 HydrophobicContact CD2-CB 3.81Å; F335-C348 HydrophobicContact CE2-CB 4.31Å; S338-C348 VanDerWaalsContact CB-CB 3.44Å; S338-C348 PolarHBondContact OG-SG 3.14Å; D345-C348 PolarHBondContact O-N 3.43Å; D345-C348 PolarHBondContact O-SG 3.21Å
349	M	83.9	Confident	82.6	Confident	11 Å²	11	51 Å²	51	5%	0.054	25%	0.248	C	C	.	.			trans	-63.1	141.3	177.3	-68.1	175.7	178.5	0	0	111.5	F346 P359 Q483 V489 L490	F346-M349 HydrophobicContact CB-CE 3.93Å; F346-M349 HydrophobicContact CB-SD 4.14Å; M349-P359 HydrophobicContact CB-CG 4.34Å; M349-Q483 HydrophobicContact CE-CB 4.41Å; M349-Q483 HydrophobicContact CE-CG 4.43Å; M349-Q483 HydrophobicContact SD-CB 4.21Å; M349-Q483 HydrophobicContact SD-CG 4.25Å; M349-V489 CarbonylContact C-O 3.51Å; M349-V489 VanDerWaalsContact CA-O 3.31Å; M349-V489 WeakPolarHBondContact CA-O 3.36Å; M349-L490 HydrophobicContact CE-CD1 3.72Å; M349-L490 HydrophobicContact CG-CD1 3.88Å
350	I	84.7	Confident	83.2	Confident	35 Å²	35	45.9 Å²	45.9	18%	0.179	23%	0.229	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-112.6	137.8	-179.1	-58.4	-168.4	0	0	0	109.6	F335 V352 S488 V489 T491	F335-I350 HydrophobicContact CE2-CD1 3.95Å; F335-I350 HydrophobicContact CE2-CG1 4.33Å; I350-V352 PolarHBondContact O-N 3.41Å; I350-S488 CarbonylContact O-C 3.4Å; I350-S488 VanDerWaalsContact O-CA 3.22Å; I350-S488 WeakPolarHBondContact O-CA 3.42Å; I350-S488 WeakPolarHBondContact O-CB 3.39Å; I350-V489 PolarHBondContact N-O 2.9Å; I350-V489 PolarHBondContact O-N 3.28Å; I350-T491 HydrophobicContact CB-CG2 4.45Å; I350-T491 HydrophobicContact CD1-CG2 3.3Å; I350-T491 HydrophobicContact CG1-CG2 3.85Å
351	H	86.3	Confident	83.6	Confident	23 Å²	23	42.1 Å²	42.1	11%	0.106	21%	0.212	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-65.6	130.8	177.1	-176.9	-71.8	0	0	0	112.1	H353 R354 Y355 T356 I358 C486	H351-H353 PolarHBondContact ND1-N 3.19Å; H351-H353 VanDerWaalsContact ND1-N 3.17Å; H351-H353 PolarHBondContact O-N 3.04Å; H351-R354 HydrophobicContact CB-CB 4.25Å; H351-R354 PolarHBondContact ND1-N 3Å; H351-R354 PolarHBondContact O-N 3.27Å; H351-Y355 WeakPolarHBondContact O-CA 3.26Å; H351-Y355 PolarHBondContact O-N 2.74Å; H351-T356 PolarHBondContact N-O 2.84Å; H351-I358 HydrophobicContact CB-CD1 3.68Å; H351-I358 HydrophobicContact CB-CG1 4.1Å; H351-I358 VanDerWaalsContact CD2-CD1 3.41Å; H351-I358 WeakPolarHBondContact CD2-CD1 3.43Å; H351-C486 PolarHBondContact CD2-O 3.47Å
352	V	84.1	Confident	84.1	Confident	50 Å²	50	44.2 Å²	44.2	30%	0.303	21%	0.212	S	C	.	.	T	Hydrogen-bonded Turn	trans	-55.5	-47.7	-170.3	178.4	0	0	0	0	113.7	I350 Y487 V489	I350-V352 PolarHBondContact O-N 3.41Å; V352-Y487 HydrophobicContact CB-CD1 4.02Å; V352-Y487 HydrophobicContact CB-CE1 3.76Å; V352-Y487 HydrophobicContact CG1-CE1 4.26Å; V352-Y487 HydrophobicContact CG2-CD1 4.11Å; V352-Y487 HydrophobicContact CG2-CE1 3.98Å; V352-Y487 PolarHBondContact N-O 3.11Å; V352-V489 HydrophobicContact CG2-CG1 3.81Å; V352-V489 HydrophobicContact CG2-CG2 4.01Å
353	H	82.8	Confident	84.4	Confident	136 Å²	136	46.2 Å²	46.2	63%	0.63	22%	0.221	S	C	*	.	T	Hydrogen-bonded Turn	trans	-90.9	-19.5	-176.6	-61.9	-61.2	0	0	0	115	H351 Y487	H351-H353 PolarHBondContact ND1-N 3.19Å; H351-H353 VanDerWaalsContact ND1-N 3.17Å; H351-H353 PolarHBondContact O-N 3.04Å; H353-Y487 AromaticContact CD2-CE1 3.69Å; H353-Y487 AromaticContact NE2-CE1 3.59Å
354	R	78.6	Confident	84.8	Confident	118 Å²	118	45.7 Å²	45.7	45%	0.445	22%	0.218	S	C	.	.	T	Hydrogen-bonded Turn	trans	-108.8	-18.9	-167.4	-66.3	177.8	179.6	-165.9	-0.3	112.1	A174 H351 T356	A174-R354 WeakPolarHBondContact O-CD 3.38Å; H351-R354 HydrophobicContact CB-CB 4.25Å; H351-R354 PolarHBondContact ND1-N 3Å; H351-R354 PolarHBondContact O-N 3.27Å; R354-T356 HydrophobicContact CB-CG2 4.13Å; R354-T356 WeakPolarHBondContact O-CG2 3.41Å; R354-T356 PolarHBondContact O-N 3.46Å
355	Y	81.7	Confident	85.3	Confident	188 Å²	188	43.7 Å²	43.7	74%	0.737	21%	0.206	S	C	*	.			trans	56.8	35.8	-177	-55.3	-84.5	0	0	0	112.5	H351	H351-Y355 WeakPolarHBondContact O-CA 3.26Å; H351-Y355 PolarHBondContact O-N 2.74Å
356	T	82.6	Confident	86.1	Confident	1 Å²	1	45.7 Å²	45.7	1%	0.006	21%	0.211	C	C	.	.			trans	-115	140.8	-179.3	59.1	0	0	0	0	111.7	C173 V176 H351 R354 I358	C173-T356 PolarHBondContact O-OG1 3.26Å; V176-T356 HydrophobicContact CB-CG2 4.34Å; V176-T356 HydrophobicContact CG2-CG2 3.46Å; V176-T356 VanDerWaalsContact CG2-CG2 3.46Å; H351-T356 PolarHBondContact N-O 2.84Å; R354-T356 HydrophobicContact CB-CG2 4.13Å; R354-T356 WeakPolarHBondContact O-CG2 3.41Å; R354-T356 PolarHBondContact O-N 3.46Å; T356-I358 VanDerWaalsContact C-N 3.31Å; T356-I358 PolarHBondContact O-N 3.42Å
357	P	86.7	Confident	86.7	Confident	21 Å²	21	45.2 Å²	45.2	14%	0.136	21%	0.209	C	C	.	.			trans	-82.8	71.1	-179.1	34.4	-36.3	0	0	0	111.5	A360 L361	P357-A360 HydrophobicContact CB-CB 4.32Å; P357-A360 PolarHBondContact O-N 2.95Å; P357-L361 HydrophobicContact CG-CD1 4.47Å; P357-L361 HydrophobicContact CG-CG 4.49Å; P357-L361 WeakPolarHBondContact O-CG 3.47Å; P357-L361 PolarHBondContact O-N 3.33Å; P357-L361 VanDerWaalsContact O-N 3.16Å
358	I	88.4	Confident	87.4	Confident	18 Å²	18	44.4 Å²	44.4	9%	0.092	21%	0.205	C	C	.	.	H	α-helix	trans	-56.8	-46.9	-173.5	-62.1	-178.9	0	0	0	113.2	C173 H351 T356 A360 L361 L362 C486	C173-I358 HydrophobicContact CB-CG1 4.18Å; H351-I358 HydrophobicContact CB-CD1 3.68Å; H351-I358 HydrophobicContact CB-CG1 4.1Å; H351-I358 VanDerWaalsContact CD2-CD1 3.41Å; H351-I358 WeakPolarHBondContact CD2-CD1 3.43Å; T356-I358 VanDerWaalsContact C-N 3.31Å; T356-I358 PolarHBondContact O-N 3.42Å; I358-A360 PolarHBondContact O-N 3.22Å; I358-L361 PolarHBondContact O-N 3Å; I358-L362 HydrophobicContact CG2-CD1 3.74Å; I358-L362 HydrophobicContact CG2-CG 4.01Å; I358-L362 WeakPolarHBondContact O-CG 3.41Å; I358-L362 PolarHBondContact O-N 3.45Å; I358-C486 HydrophobicContact CB-CB 4.46Å; I358-C486 HydrophobicContact CG2-CB 4.19Å
359	P	89.1	Confident	88.3	Confident	9 Å²	9	46.6 Å²	46.6	6%	0.058	22%	0.216	C	C	.	.	H	α-helix	trans	-60.9	-41.3	-178.1	-26.2	37.6	0	0	0	113.6	F346 M349 L362 F363 I482 C486	F346-P359 VanDerWaalsContact O-CB 3.3Å; F346-P359 WeakPolarHBondContact O-CB 3.24Å; M349-P359 HydrophobicContact CB-CG 4.34Å; P359-L362 PolarHBondContact O-N 3.22Å; P359-F363 WeakPolarHBondContact O-CB 3.27Å; P359-F363 PolarHBondContact O-N 3.16Å; P359-I482 HydrophobicContact CB-CG2 3.81Å; P359-I482 HydrophobicContact CG-CG2 3.51Å; P359-C486 HydrophobicContact CG-CB 4.28Å
360	A	87.9	Confident	88.8	Confident	1 Å²	1	49.9 Å²	49.9	1%	0.008	23%	0.233	C	C	.	.	H	α-helix	trans	-61.3	-45.5	174.5	0	0	0	0	0	112	F334 L347 P357 I358 F363 N364	F334-A360 HydrophobicContact CB-CB 4.18Å; F334-A360 HydrophobicContact CD2-CB 3.74Å; F334-A360 HydrophobicContact CG-CB 4.46Å; L347-A360 WeakPolarHBondContact O-CB 3.44Å; P357-A360 HydrophobicContact CB-CB 4.32Å; P357-A360 PolarHBondContact O-N 2.95Å; I358-A360 PolarHBondContact O-N 3.22Å; A360-F363 PolarHBondContact O-N 3.47Å; A360-N364 WeakPolarHBondContact O-CB 3.48Å; A360-N364 PolarHBondContact O-N 3.01Å
361	L	89.9	Confident	89.2	Confident	3 Å²	3	49.6 Å²	49.6	2%	0.016	23%	0.23	C	C	.	.	H	α-helix	trans	-63.5	-42.3	179.6	-70.1	169.4	0	0	0	111.9	T169 N172 I327 P357 I358 G365	T169-L361 HydrophobicContact CG2-CB 4.3Å; T169-L361 WeakPolarHBondContact CG2-O 3.44Å; N172-L361 HydrophobicContact CB-CD1 4.01Å; N172-L361 HydrophobicContact CB-CD2 4.13Å; I327-L361 HydrophobicContact CG2-CD2 3.46Å; I327-L361 VanDerWaalsContact CG2-CD2 3.46Å; P357-L361 HydrophobicContact CG-CD1 4.47Å; P357-L361 HydrophobicContact CG-CG 4.49Å; P357-L361 WeakPolarHBondContact O-CG 3.47Å; P357-L361 PolarHBondContact O-N 3.33Å; P357-L361 VanDerWaalsContact O-N 3.16Å; I358-L361 PolarHBondContact O-N 3Å; L361-G365 PolarHBondContact O-N 3.24Å
362	L	91.8	Very high	89.6	Confident	89 Å²	89	49 Å²	49	47%	0.466	23%	0.227	S	C	.	.	H	α-helix	trans	-66.5	-42.9	177	-68.8	179.1	0	0	0	111.9	T169 I358 P359 G365 F366	T169-L362 HydrophobicContact CG2-CD2 4.4Å; I358-L362 HydrophobicContact CG2-CD1 3.74Å; I358-L362 HydrophobicContact CG2-CG 4.01Å; I358-L362 WeakPolarHBondContact O-CG 3.41Å; I358-L362 PolarHBondContact O-N 3.45Å; P359-L362 PolarHBondContact O-N 3.22Å; L362-G365 PolarHBondContact O-N 3.28Å; L362-F366 VanDerWaalsContact O-CB 3.27Å; L362-F366 WeakPolarHBondContact O-CB 3.31Å; L362-F366 PolarHBondContact O-N 3Å
363	F	91	Very high	90	Very high	64 Å²	64	51.5 Å²	51.5	28%	0.281	25%	0.246	S	C	.	.	H	α-helix	trans	-61.4	-49	176.3	177.6	-98.2	0	0	0	111.4	L123 L124 F334 L347 P359 A360 F366 M367	L123-F363 HydrophobicContact CD2-CD1 4.23Å; L123-F363 HydrophobicContact CD2-CE1 3.81Å; L124-F363 HydrophobicContact CD2-CZ 4.18Å; F334-F363 AromaticContact CE2-CD1 3.97Å; F334-F363 HydrophobicContact CE2-CD1 3.97Å; L347-F363 HydrophobicContact CD2-CB 4.16Å; L347-F363 HydrophobicContact CD2-CG 4.37Å; P359-F363 WeakPolarHBondContact O-CB 3.27Å; P359-F363 PolarHBondContact O-N 3.16Å; A360-F363 PolarHBondContact O-N 3.47Å; F363-F366 PolarHBondContact O-N 3.43Å; F363-M367 HydrophobicContact CD1-CG 4.41Å; F363-M367 HydrophobicContact CE1-CG 3.96Å; F363-M367 HydrophobicContact CE2-CG 4.22Å; F363-M367 HydrophobicContact CZ-CG 3.85Å; F363-M367 HydrophobicContact CZ-SD 4.31Å; F363-M367 WeakPolarHBondContact O-CG 3.27Å; F363-M367 PolarHBondContact O-N 2.99Å
364	N	91.4	Very high	90.3	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-61	-47	177.9	-177.4	54.8	0	0	0	111.9	Q131 F334 A360 F366 M367 A368	Q131-N364 VanDerWaalsContact CD-ND2 3.26Å; Q131-N364 PolarHBondContact NE2-ND2 3.31Å; Q131-N364 PolarHBondContact NE2-OD1 3.36Å; Q131-N364 VanDerWaalsContact NE2-OD1 3.14Å; Q131-N364 PolarHBondContact OE1-ND2 2.64Å; Q131-N364 PolarHBondContact OE1-OD1 2.96Å; F334-N364 HydrophobicContact CE2-CB 3.81Å; F334-N364 HydrophobicContact CZ-CB 4.18Å; A360-N364 WeakPolarHBondContact O-CB 3.48Å; A360-N364 PolarHBondContact O-N 3.01Å; N364-F366 PolarHBondContact O-N 3.21Å; N364-M367 PolarHBondContact O-N 2.92Å; N364-A368 WeakPolarHBondContact O-CB 3.1Å; N364-A368 PolarHBondContact O-N 3.03Å
365	G	93.1	Very high	90.7	Very high	5 Å²	5	48.4 Å²	48.4	5%	0.052	24%	0.239	C	C	.	.	H	α-helix	trans	-60.8	-43.6	177.6	0	0	0	0	0	112.2	L361 L362 A368 L369	L361-G365 PolarHBondContact O-N 3.24Å; L362-G365 PolarHBondContact O-N 3.28Å; G365-A368 PolarHBondContact O-N 3.39Å; G365-L369 WeakPolarHBondContact O-CG 3.31Å; G365-L369 PolarHBondContact O-N 3.27Å
366	F	94.6	Very high	91	Very high	128 Å²	128	42.3 Å²	42.3	56%	0.561	22%	0.219	S	C	*	.	H	α-helix	trans	-61.3	-45.1	175.5	176.3	-105.1	0	0	0	112.4	L362 F363 N364 A368 L369 I370	L362-F366 VanDerWaalsContact O-CB 3.27Å; L362-F366 WeakPolarHBondContact O-CB 3.31Å; L362-F366 PolarHBondContact O-N 3Å; F363-F366 PolarHBondContact O-N 3.43Å; N364-F366 PolarHBondContact O-N 3.21Å; F366-A368 VanDerWaalsContact C-N 3.33Å; F366-A368 PolarHBondContact O-N 3.42Å; F366-L369 WeakPolarHBondContact O-CB 3.24Å; F366-L369 PolarHBondContact O-N 3.02Å; F366-I370 HydrophobicContact CD1-CD1 4.02Å; F366-I370 HydrophobicContact CE1-CD1 3.49Å; F366-I370 VanDerWaalsContact CE1-CD1 3.49Å; F366-I370 HydrophobicContact CE1-CG1 4.39Å; F366-I370 HydrophobicContact CZ-CD1 3.82Å; F366-I370 HydrophobicContact CZ-CG1 4.36Å; F366-I370 PolarHBondContact O-N 3.02Å; F366-I370 VanDerWaalsContact O-N 3.16Å
367	M	94.3	Very high	91.4	Very high	25 Å²	25	43.1 Å²	43.1	12%	0.123	22%	0.224	C	C	.	.	H	α-helix	trans	-61.5	-42	175.6	-72.7	-60.4	-58.8	0	0	111.7	L124 P128 F363 N364 L369 I370 Y371	L124-M367 HydrophobicContact CD2-CE 3.8Å; L124-M367 HydrophobicContact CD2-SD 4.31Å; P128-M367 HydrophobicContact CB-CB 3.77Å; P128-M367 HydrophobicContact CG-CB 3.55Å; P128-M367 HydrophobicContact CG-CG 4.44Å; F363-M367 HydrophobicContact CD1-CG 4.41Å; F363-M367 HydrophobicContact CE1-CG 3.96Å; F363-M367 HydrophobicContact CE2-CG 4.22Å; F363-M367 HydrophobicContact CZ-CG 3.85Å; F363-M367 HydrophobicContact CZ-SD 4.31Å; F363-M367 WeakPolarHBondContact O-CG 3.27Å; F363-M367 PolarHBondContact O-N 2.99Å; N364-M367 PolarHBondContact O-N 2.92Å; M367-L369 VanDerWaalsContact C-N 3.29Å; M367-L369 PolarHBondContact O-N 3.04Å; M367-I370 WeakPolarHBondContact O-CB 3.49Å; M367-I370 PolarHBondContact O-N 3.11Å; M367-I370 VanDerWaalsContact O-N 3.13Å; M367-I370 HydrophobicContact SD-CD1 4.08Å; M367-Y371 HydrophobicContact CE-CE2 4.22Å; M367-Y371 WeakPolarHBondContact O-CD2 3.5Å; M367-Y371 PolarHBondContact O-N 3.13Å
368	A	95.1	Very high	91.5	Very high	0 Å²	0	43.6 Å²	43.6	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-63.1	-36.2	178	0	0	0	0	0	111.9	P128 Q131 I165 N364 G365 F366 I370 Y371 L372	P128-A368 HydrophobicContact CB-CB 4.48Å; Q131-A368 HydrophobicContact CB-CB 4.09Å; I165-A368 HydrophobicContact CD1-CB 3.96Å; I165-A368 HydrophobicContact CG2-CB 4.32Å; N364-A368 WeakPolarHBondContact O-CB 3.1Å; N364-A368 PolarHBondContact O-N 3.03Å; G365-A368 PolarHBondContact O-N 3.39Å; F366-A368 VanDerWaalsContact C-N 3.33Å; F366-A368 PolarHBondContact O-N 3.42Å; A368-I370 PolarHBondContact O-N 3.28Å; A368-Y371 PolarHBondContact O-N 2.89Å; A368-L372 PolarHBondContact O-N 3.42Å
369	L	96.1	Very high	91.6	Very high	54 Å²	54	48.9 Å²	48.9	28%	0.283	24%	0.243	S	C	.	.	H	α-helix	trans	-63.9	-36.2	173.2	-67.6	175	0	0	0	112.7	A162 I165 G365 F366 M367 Y371 L372	A162-L369 HydrophobicContact CB-CD2 3.72Å; I165-L369 HydrophobicContact CB-CD2 4.47Å; I165-L369 HydrophobicContact CG2-CD2 4.46Å; G365-L369 WeakPolarHBondContact O-CG 3.31Å; G365-L369 PolarHBondContact O-N 3.27Å; F366-L369 WeakPolarHBondContact O-CB 3.24Å; F366-L369 PolarHBondContact O-N 3.02Å; M367-L369 VanDerWaalsContact C-N 3.29Å; M367-L369 PolarHBondContact O-N 3.04Å; L369-Y371 VanDerWaalsContact C-N 3.33Å; L369-L372 HydrophobicContact CD2-CD1 4.03Å; L369-L372 WeakPolarHBondContact O-CB 3.46Å; L369-L372 PolarHBondContact O-N 2.8Å
370	I	95.3	Very high	91.7	Very high	80 Å²	80	48.4 Å²	48.4	41%	0.41	24%	0.24	S	C	.	.	H	α-helix	trans	-62.2	-43.2	174.8	-68.3	167.9	0	0	0	110.5	F366 M367 A368 L372 C373	F366-I370 HydrophobicContact CD1-CD1 4.02Å; F366-I370 HydrophobicContact CE1-CD1 3.49Å; F366-I370 VanDerWaalsContact CE1-CD1 3.49Å; F366-I370 HydrophobicContact CE1-CG1 4.39Å; F366-I370 HydrophobicContact CZ-CD1 3.82Å; F366-I370 HydrophobicContact CZ-CG1 4.36Å; F366-I370 PolarHBondContact O-N 3.02Å; F366-I370 VanDerWaalsContact O-N 3.16Å; M367-I370 WeakPolarHBondContact O-CB 3.49Å; M367-I370 PolarHBondContact O-N 3.11Å; M367-I370 VanDerWaalsContact O-N 3.13Å; M367-I370 HydrophobicContact SD-CD1 4.08Å; A368-I370 PolarHBondContact O-N 3.28Å; I370-L372 PolarHBondContact O-N 2.95Å; I370-C373 VanDerWaalsContact O-CB 3.27Å; I370-C373 WeakPolarHBondContact O-CB 3.2Å; I370-C373 PolarHBondContact O-N 3.49Å
371	Y	93.8	Very high	91.9	Very high	29 Å²	29	48.4 Å²	48.4	11%	0.114	24%	0.24	C	C	.	.	H	α-helix	trans	-69.3	-20	178.8	-81.3	-79.8	0	0	0	113.5	L124 P128 T129 M367 A368 L369 C373 V374 L380	L124-Y371 WeakPolarHBondContact O-CE2 3.29Å; L124-Y371 PolarHBondContact O-OH 3.34Å; P128-Y371 HydrophobicContact CB-CD2 3.61Å; P128-Y371 HydrophobicContact CB-CE2 3.91Å; T129-Y371 WeakPolarHBondContact OG1-CE1 3.4Å; M367-Y371 HydrophobicContact CE-CE2 4.22Å; M367-Y371 WeakPolarHBondContact O-CD2 3.5Å; M367-Y371 PolarHBondContact O-N 3.13Å; A368-Y371 PolarHBondContact O-N 2.89Å; L369-Y371 VanDerWaalsContact C-N 3.33Å; Y371-C373 PolarHBondContact O-N 3.35Å; Y371-V374 HydrophobicContact CD1-CG2 4.41Å; Y371-V374 WeakPolarHBondContact O-CB 3.31Å; Y371-V374 PolarHBondContact O-N 3.27Å; Y371-V374 VanDerWaalsContact O-N 3.1Å; Y371-L380 HydrophobicContact CD1-CD2 3.52Å; Y371-L380 HydrophobicContact CE1-CD2 4.42Å; Y371-L380 HydrophobicContact CG-CD2 4.26Å
372	L	93.9	Very high	91.9	Very high	10 Å²	10	49 Å²	49	5%	0.052	24%	0.243	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65	-18.2	169.8	-69.6	-176.3	0	0	0	113.3	A132 A135 I136 R158 A161 A162 I165 A368 L369 I370 V374	A132-L372 HydrophobicContact CB-CD2 4.07Å; A135-L372 HydrophobicContact CB-CD2 4.5Å; I136-L372 HydrophobicContact CD1-CD2 3.96Å; I136-L372 HydrophobicContact CG1-CD2 3.6Å; R158-L372 PolarHBondContact NH1-O 2.81Å; A161-L372 HydrophobicContact CB-CD1 4.17Å; A161-L372 HydrophobicContact CB-CD2 4.03Å; A162-L372 HydrophobicContact CB-CD1 3.72Å; I165-L372 HydrophobicContact CD1-CD1 3.83Å; I165-L372 HydrophobicContact CD1-CD2 4.39Å; I165-L372 HydrophobicContact CD1-CG 4.12Å; A368-L372 PolarHBondContact O-N 3.42Å; L369-L372 HydrophobicContact CD2-CD1 4.03Å; L369-L372 WeakPolarHBondContact O-CB 3.46Å; L369-L372 PolarHBondContact O-N 2.8Å; I370-L372 PolarHBondContact O-N 2.95Å; L372-V374 PolarHBondContact O-N 3.35Å
373	C	91.3	Very high	91.7	Very high	102 Å²	102	46.3 Å²	46.3	69%	0.689	23%	0.227	S	C	*	.	T	Hydrogen-bonded Turn	trans	-71.9	-13.4	173.5	-60.5	0	0	0	0	113	I370 Y371 E375	I370-C373 VanDerWaalsContact O-CB 3.27Å; I370-C373 WeakPolarHBondContact O-CB 3.2Å; I370-C373 PolarHBondContact O-N 3.49Å; Y371-C373 PolarHBondContact O-N 3.35Å; C373-E375 PolarHBondContact O-N 3.48Å
374	V	90.6	Very high	91.7	Very high	37 Å²	37	43.9 Å²	43.9	22%	0.224	22%	0.216	C	C	.	.			trans	-77.6	117.8	175.4	-177.3	0	0	0	0	109.3	R158 Y371 L372 D376 R379 L380	R158-V374 PolarHBondContact NH1-O 3.1Å; R158-V374 PolarHBondContact NH2-O 3.39Å; Y371-V374 HydrophobicContact CD1-CG2 4.41Å; Y371-V374 WeakPolarHBondContact O-CB 3.31Å; Y371-V374 PolarHBondContact O-N 3.27Å; Y371-V374 VanDerWaalsContact O-N 3.1Å; L372-V374 PolarHBondContact O-N 3.35Å; V374-D376 PolarHBondContact O-N 3.48Å; V374-R379 HydrophobicContact CG1-CB 4.37Å; V374-L380 HydrophobicContact CB-CD1 4.45Å; V374-L380 HydrophobicContact CB-CD2 3.78Å; V374-L380 HydrophobicContact CB-CG 4.11Å; V374-L380 HydrophobicContact CG1-CD2 4.03Å; V374-L380 HydrophobicContact CG1-CG 4.08Å; V374-L380 HydrophobicContact CG2-CD2 3.87Å
375	E	85.7	Confident	91.7	Very high	152 Å²	152	43.9 Å²	43.9	71%	0.71	22%	0.216	S	C	*	.	S	Bend	trans	-62.6	-39.8	-175.1	-67	-177.1	174.2	0	0	113.9	Y154 R158 C373	Y154-E375 HydrophobicContact CE2-CB 4.33Å; Y154-E375 HydrophobicContact CE2-CG 4.28Å; R158-E375 VanDerWaalsContact NH2-C 3.35Å; R158-E375 PolarHBondContact NH2-O 2.8Å; C373-E375 PolarHBondContact O-N 3.48Å
376	D	88.5	Confident	91.6	Very high	60 Å²	60	44.2 Å²	44.2	32%	0.321	22%	0.216	S	C	.	.			trans	-99.8	121.7	-174.4	-174.6	-3.8	0	0	0	111.8	V374 F378 R379 L380	V374-D376 PolarHBondContact O-N 3.48Å; D376-F378 VanDerWaalsContact C-N 3.33Å; D376-F378 PolarHBondContact OD1-N 3.13Å; D376-R379 HydrophobicContact CB-CB 4.23Å; D376-R379 HydrophobicContact CB-CG 3.87Å; D376-R379 PolarHBondContact O-N 2.95Å; D376-R379 IonicContact OD2-NE 3.19Å; D376-L380 PolarHBondContact O-N 3.14Å
377	V	90.5	Very high	91.5	Very high	18 Å²	18	38.3 Å²	38.3	11%	0.109	19%	0.19	C	C	.	.	H	α-helix	trans	-67.2	-33.8	177.8	-177.1	0	0	0	0	111.4	V56 V133 I136 R379 L380 I381	V56-V377 HydrophobicContact CG1-CG1 4.3Å; V133-V377 HydrophobicContact CB-CG1 4.39Å; V133-V377 HydrophobicContact CG1-CG1 3.83Å; V133-V377 HydrophobicContact CG2-CG1 4.13Å; I136-V377 HydrophobicContact CB-CG2 4.14Å; I136-V377 HydrophobicContact CD1-CG2 3.98Å; I136-V377 HydrophobicContact CG2-CG2 3.46Å; I136-V377 VanDerWaalsContact CG2-CG2 3.46Å; V377-R379 VanDerWaalsContact C-N 3.33Å; V377-R379 PolarHBondContact O-N 2.75Å; V377-L380 WeakPolarHBondContact O-CB 3.33Å; V377-L380 PolarHBondContact O-N 3.27Å; V377-I381 HydrophobicContact CG1-CD1 4.29Å; V377-I381 WeakPolarHBondContact O-CG1 3.03Å; V377-I381 PolarHBondContact O-N 3.35Å
378	F	89.6	Confident	91.3	Very high	31 Å²	31	37.4 Å²	37.4	14%	0.136	19%	0.186	C	C	.	.	H	α-helix	trans	-71.2	-30.5	-180	-66	-70.6	0	0	0	111.8	V56 K59 I63 D376 L380 I381 N382	V56-F378 HydrophobicContact CG1-CE1 4.04Å; V56-F378 HydrophobicContact CG1-CZ 4.18Å; K59-F378 HydrophobicContact CB-CZ 4.14Å; K59-F378 HydrophobicContact CD-CE2 4.37Å; K59-F378 HydrophobicContact CD-CZ 4.35Å; K59-F378 HydrophobicContact CG-CE2 4.23Å; K59-F378 HydrophobicContact CG-CZ 3.91Å; I63-F378 HydrophobicContact CD1-CE2 4.25Å; D376-F378 VanDerWaalsContact C-N 3.33Å; D376-F378 PolarHBondContact OD1-N 3.13Å; F378-L380 VanDerWaalsContact C-N 3.33Å; F378-L380 PolarHBondContact O-N 3.18Å; F378-I381 HydrophobicContact CD1-CD1 3.97Å; F378-I381 HydrophobicContact CE1-CD1 4.28Å; F378-I381 PolarHBondContact O-N 2.76Å; F378-N382 VanDerWaalsContact O-CG 3.27Å; F378-N382 PolarHBondContact O-N 3.43Å; F378-N382 PolarHBondContact O-OD1 2.82Å
379	R	90.3	Very high	91.2	Very high	129 Å²	129	37.4 Å²	37.4	49%	0.487	19%	0.186	S	C	.	.	H	α-helix	trans	-61.4	-42.4	168.8	-68.8	-177.2	-170	-179.1	-0.6	111.8	V374 D376 V377 N382 Y383	V374-R379 HydrophobicContact CG1-CB 4.37Å; D376-R379 HydrophobicContact CB-CB 4.23Å; D376-R379 HydrophobicContact CB-CG 3.87Å; D376-R379 PolarHBondContact O-N 2.95Å; D376-R379 IonicContact OD2-NE 3.19Å; V377-R379 VanDerWaalsContact C-N 3.33Å; V377-R379 PolarHBondContact O-N 2.75Å; R379-N382 PolarHBondContact O-N 3.04Å; R379-Y383 HydrophobicContact CB-CE2 4.34Å; R379-Y383 WeakPolarHBondContact O-CD2 3.26Å; R379-Y383 PolarHBondContact O-N 2.83Å
380	L	91.8	Very high	91	Very high	0 Å²	0	39.3 Å²	39.3	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-60.5	-46.1	173.8	-65.2	174.3	0	0	0	111	T129 A132 V133 I136 Y371 V374 D376 V377 F378 N382 Y383 Y384	T129-L380 HydrophobicContact CG2-CB 3.67Å; T129-L380 HydrophobicContact CG2-CD2 3.94Å; T129-L380 HydrophobicContact CG2-CG 4.4Å; T129-L380 WeakPolarHBondContact CG2-O 3.27Å; A132-L380 HydrophobicContact CB-CD1 4.17Å; V133-L380 HydrophobicContact CG2-CB 3.5Å; V133-L380 VanDerWaalsContact CG2-CB 3.5Å; V133-L380 HydrophobicContact CG2-CD1 4.12Å; V133-L380 HydrophobicContact CG2-CG 4.46Å; I136-L380 HydrophobicContact CD1-CD1 3.72Å; Y371-L380 HydrophobicContact CD1-CD2 3.52Å; Y371-L380 HydrophobicContact CE1-CD2 4.42Å; Y371-L380 HydrophobicContact CG-CD2 4.26Å; V374-L380 HydrophobicContact CB-CD1 4.45Å; V374-L380 HydrophobicContact CB-CD2 3.78Å; V374-L380 HydrophobicContact CB-CG 4.11Å; V374-L380 HydrophobicContact CG1-CD2 4.03Å; V374-L380 HydrophobicContact CG1-CG 4.08Å; V374-L380 HydrophobicContact CG2-CD2 3.87Å; D376-L380 PolarHBondContact O-N 3.14Å; V377-L380 WeakPolarHBondContact O-CB 3.33Å; V377-L380 PolarHBondContact O-N 3.27Å; F378-L380 VanDerWaalsContact C-N 3.33Å; F378-L380 PolarHBondContact O-N 3.18Å; L380-N382 VanDerWaalsContact C-N 3.28Å; L380-N382 PolarHBondContact O-N 2.95Å; L380-Y383 HydrophobicContact CD2-CD2 4.49Å; L380-Y383 PolarHBondContact O-N 3.43Å; L380-Y384 WeakPolarHBondContact O-CB 3.4Å; L380-Y384 PolarHBondContact O-N 3.46Å
381	I	91.6	Very high	90.9	Very high	0 Å²	0	35.7 Å²	35.7	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-58.8	-40	176.1	-68.2	169.8	0	0	0	111.4	V56 V133 F236 V377 F378 S385	V56-I381 HydrophobicContact CG1-CD1 3.92Å; V133-I381 HydrophobicContact CG1-CD1 4.32Å; V133-I381 HydrophobicContact CG1-CG1 4.09Å; V133-I381 HydrophobicContact CG2-CG1 4.06Å; F236-I381 HydrophobicContact CB-CG2 3.84Å; F236-I381 HydrophobicContact CD1-CD1 4.22Å; F236-I381 HydrophobicContact CD1-CG1 4.23Å; F236-I381 HydrophobicContact CD2-CG1 4.39Å; F236-I381 HydrophobicContact CD2-CG2 4.38Å; F236-I381 HydrophobicContact CE1-CD1 4.49Å; F236-I381 HydrophobicContact CE1-CG1 4.4Å; F236-I381 HydrophobicContact CG-CG1 4.23Å; F236-I381 HydrophobicContact CG-CG2 4.05Å; V377-I381 HydrophobicContact CG1-CD1 4.29Å; V377-I381 WeakPolarHBondContact O-CG1 3.03Å; V377-I381 PolarHBondContact O-N 3.35Å; F378-I381 HydrophobicContact CD1-CD1 3.97Å; F378-I381 HydrophobicContact CE1-CD1 4.28Å; F378-I381 PolarHBondContact O-N 2.76Å; I381-S385 WeakPolarHBondContact O-CB 3.44Å; I381-S385 PolarHBondContact O-N 3.41Å; I381-S385 PolarHBondContact O-OG 3.4Å
382	N	89.5	Confident	90.9	Very high	15 Å²	15	34.4 Å²	34.4	8%	0.08	17%	0.168	C	C	.	.	H	α-helix	trans	-67.6	-44.6	177.6	-69.1	-5.3	0	0	0	112.1	Y232 F378 R379 L380 Y384 S385 F386 D438	Y232-N382 HydrophobicContact CD2-CB 4.45Å; F378-N382 VanDerWaalsContact O-CG 3.27Å; F378-N382 PolarHBondContact O-N 3.43Å; F378-N382 PolarHBondContact O-OD1 2.82Å; R379-N382 PolarHBondContact O-N 3.04Å; L380-N382 VanDerWaalsContact C-N 3.28Å; L380-N382 PolarHBondContact O-N 2.95Å; N382-Y384 VanDerWaalsContact C-N 3.34Å; N382-Y384 PolarHBondContact O-N 3.21Å; N382-S385 PolarHBondContact O-N 3.09Å; N382-F386 WeakPolarHBondContact O-CB 3.29Å; N382-F386 PolarHBondContact O-N 2.93Å; N382-D438 PolarHBondContact ND2-OD2 3.42Å
383	Y	87	Confident	90.9	Very high	33 Å²	33	34.1 Å²	34.1	13%	0.129	17%	0.168	C	C	.	.	H	α-helix	trans	-58.1	-46.9	175.7	-71.1	-47.4	0	0	0	112.3	R379 L380 S387 N441 I444	R379-Y383 HydrophobicContact CB-CE2 4.34Å; R379-Y383 WeakPolarHBondContact O-CD2 3.26Å; R379-Y383 PolarHBondContact O-N 2.83Å; L380-Y383 HydrophobicContact CD2-CD2 4.49Å; L380-Y383 PolarHBondContact O-N 3.43Å; Y383-S387 PolarHBondContact O-N 3.38Å; Y383-S387 PolarHBondContact O-OG 3.4Å; Y383-N441 HydrophobicContact CD1-CB 3.96Å; Y383-N441 VanDerWaalsContact CE1-CA 3.48Å; Y383-N441 HydrophobicContact CE1-CB 3.47Å; Y383-N441 VanDerWaalsContact CE1-CB 3.47Å; Y383-N441 WeakPolarHBondContact CE1-O 3.23Å; Y383-N441 PolarHBondContact OH-OD1 2.95Å; Y383-I444 HydrophobicContact CE1-CB 4.19Å; Y383-I444 HydrophobicContact CE1-CD1 4.4Å; Y383-I444 HydrophobicContact CE1-CG2 4.24Å
384	Y	91.5	Very high	91.1	Very high	13 Å²	13	30.4 Å²	30.4	5%	0.051	14%	0.141	C	C	.	.	H	α-helix	trans	-59.6	-54.9	175.2	168.6	-93.1	0	0	0	110.5	I126 F236 S239 L380 N382 F386 S387 Y388	I126-Y384 HydrophobicContact CB-CD2 4.44Å; I126-Y384 HydrophobicContact CG2-CD2 3.75Å; I126-Y384 HydrophobicContact CG2-CE2 3.44Å; I126-Y384 VanDerWaalsContact CG2-CE2 3.44Å; I126-Y384 WeakPolarHBondContact O-CD2 3.28Å; F236-Y384 AromaticContact CD2-CD1 3.54Å; F236-Y384 HydrophobicContact CD2-CD1 3.54Å; F236-Y384 AromaticContact CD2-CE1 3.61Å; F236-Y384 HydrophobicContact CD2-CE1 3.61Å; F236-Y384 HydrophobicContact CD2-CG 4.35Å; F236-Y384 AromaticContact CE2-CD1 4Å; F236-Y384 HydrophobicContact CE2-CD1 4Å; F236-Y384 HydrophobicContact CE2-CE1 4.08Å; F236-Y384 HydrophobicContact CE2-CG 4.4Å; S239-Y384 WeakPolarHBondContact CB-OH 3.23Å; S239-Y384 PolarHBondContact OG-OH 2.89Å; L380-Y384 WeakPolarHBondContact O-CB 3.4Å; L380-Y384 PolarHBondContact O-N 3.46Å; N382-Y384 VanDerWaalsContact C-N 3.34Å; N382-Y384 PolarHBondContact O-N 3.21Å; Y384-F386 PolarHBondContact O-N 2.9Å; Y384-S387 PolarHBondContact O-N 3.48Å; Y384-Y388 HydrophobicContact CE1-CD1 4.44Å; Y384-Y388 HydrophobicContact CE1-CG 4.28Å; Y384-Y388 HydrophobicContact CE2-CD2 4.38Å; Y384-Y388 HydrophobicContact CE2-CG 4.5Å; Y384-Y388 WeakPolarHBondContact O-CB 3.32Å; Y384-Y388 PolarHBondContact O-N 3.48Å
385	S	91.8	Very high	91.2	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-63.4	-44.9	-170.9	-62.8	0	0	0	0	111.9	I381 N382 S387 Y388 W389	I381-S385 WeakPolarHBondContact O-CB 3.44Å; I381-S385 PolarHBondContact O-N 3.41Å; I381-S385 PolarHBondContact O-OG 3.4Å; N382-S385 PolarHBondContact O-N 3.09Å; S385-S387 PolarHBondContact O-N 3.23Å; S385-Y388 PolarHBondContact O-N 3.33Å; S385-W389 WeakPolarHBondContact O-CB 3.4Å; S385-W389 PolarHBondContact O-N 3.22Å
386	F	91.1	Very high	91.6	Very high	12 Å²	12	21.5 Å²	21.5	5%	0.053	10%	0.097	C	C	.	.	H	α-helix	trans	-56.7	-52.7	177.5	176.5	-91.9	0	0	0	111.7	Y232 N382 Y384 F390 V431 L435 I446	Y232-F386 HydrophobicContact CE2-CB 4.2Å; Y232-F386 WeakPolarHBondContact OH-CA 3.19Å; N382-F386 WeakPolarHBondContact O-CB 3.29Å; N382-F386 PolarHBondContact O-N 2.93Å; Y384-F386 PolarHBondContact O-N 2.9Å; F386-F390 WeakPolarHBondContact O-CB 3.35Å; F386-F390 PolarHBondContact O-N 2.89Å; F386-F390 VanDerWaalsContact O-N 3.11Å; F386-V431 HydrophobicContact CE2-CG1 3.82Å; F386-V431 HydrophobicContact CZ-CG1 4.16Å; F386-L435 HydrophobicContact CE2-CD2 4.26Å; F386-L435 HydrophobicContact CE2-CG 4.21Å; F386-L435 HydrophobicContact CZ-CD2 4.33Å; F386-I446 HydrophobicContact CE1-CD1 4.38Å; F386-I446 HydrophobicContact CE1-CG1 3.77Å; F386-I446 HydrophobicContact CZ-CD1 3.93Å; F386-I446 HydrophobicContact CZ-CG1 3.83Å
387	S	91.4	Very high	92	Very high	4 Å²	4	22.5 Å²	22.5	3%	0.028	10%	0.102	C	C	.	.	H	α-helix	trans	-67.3	-44.8	-177	-54.8	0	0	0	0	111.4	Y383 Y384 S385 F391	Y383-S387 PolarHBondContact O-N 3.38Å; Y383-S387 PolarHBondContact O-OG 3.4Å; Y384-S387 PolarHBondContact O-N 3.48Å; S385-S387 PolarHBondContact O-N 3.23Å; S387-F391 WeakPolarHBondContact O-CD2 3.3Å; S387-F391 PolarHBondContact O-N 2.99Å
388	Y	91.8	Very high	92.1	Very high	7 Å²	7	21.7 Å²	21.7	3%	0.027	10%	0.097	C	C	.	.	H	α-helix	trans	-61.3	-52.6	-179.8	-178.7	-100.3	0	0	0	111.3	I126 D242 Y384 S385 F390 F391 V392	I126-Y388 HydrophobicContact CG2-CD2 4.06Å; D242-Y388 VanDerWaalsContact CG-OH 3.22Å; D242-Y388 PolarHBondContact OD1-OH 3.42Å; D242-Y388 PolarHBondContact OD2-OH 2.85Å; Y384-Y388 HydrophobicContact CE1-CD1 4.44Å; Y384-Y388 HydrophobicContact CE1-CG 4.28Å; Y384-Y388 HydrophobicContact CE2-CD2 4.38Å; Y384-Y388 HydrophobicContact CE2-CG 4.5Å; Y384-Y388 WeakPolarHBondContact O-CB 3.32Å; Y384-Y388 PolarHBondContact O-N 3.48Å; S385-Y388 PolarHBondContact O-N 3.33Å; Y388-F390 VanDerWaalsContact C-N 3.35Å; Y388-F390 PolarHBondContact O-N 3.29Å; Y388-F391 PolarHBondContact O-N 3.25Å; Y388-V392 HydrophobicContact CD1-CG2 4.05Å; Y388-V392 HydrophobicContact CD2-CG2 4.41Å; Y388-V392 HydrophobicContact CE1-CG2 3.73Å; Y388-V392 HydrophobicContact CE2-CG2 4.11Å; Y388-V392 HydrophobicContact CG-CG2 4.38Å; Y388-V392 VanDerWaalsContact O-CG2 3.27Å; Y388-V392 WeakPolarHBondContact O-CG2 3.39Å; Y388-V392 PolarHBondContact O-N 3.04Å
389	W	92	Very high	92.3	Very high	0 Å²	0	20.4 Å²	20.4	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-68.2	-31.9	-177.6	-68.3	119.3	0	0	0	113.3	F81 L235 W241 S385 V392 G393 F423 L430	F81-W389 HydrophobicContact CD1-CH2 4.35Å; F81-W389 HydrophobicContact CD1-CZ3 4.39Å; F81-W389 HydrophobicContact CE1-CD2 4.14Å; F81-W389 AromaticContact CE1-CE3 3.65Å; F81-W389 HydrophobicContact CE1-CE3 3.65Å; F81-W389 AromaticContact CE1-CH2 3.7Å; F81-W389 HydrophobicContact CE1-CH2 3.7Å; F81-W389 HydrophobicContact CE1-CZ2 4.19Å; F81-W389 AromaticContact CE1-CZ3 3.4Å; F81-W389 HydrophobicContact CE1-CZ3 3.4Å; F81-W389 VanDerWaalsContact CE1-CZ3 3.4Å; F81-W389 AromaticContact CZ-CE3 3.94Å; F81-W389 HydrophobicContact CZ-CE3 3.94Å; F81-W389 HydrophobicContact CZ-CZ3 4.04Å; L235-W389 HydrophobicContact CB-CZ2 3.63Å; L235-W389 HydrophobicContact CD1-CZ2 4.1Å; L235-W389 HydrophobicContact CD2-CH2 4.37Å; L235-W389 HydrophobicContact CD2-CZ2 3.98Å; L235-W389 HydrophobicContact CG-CZ2 4.11Å; W241-W389 HydrophobicContact CZ2-CH2 4.28Å; W241-W389 HydrophobicContact CZ2-CZ3 4.11Å; S385-W389 WeakPolarHBondContact O-CB 3.4Å; S385-W389 PolarHBondContact O-N 3.22Å; W389-V392 HydrophobicContact CE3-CB 4.12Å; W389-V392 HydrophobicContact CE3-CG1 4.08Å; W389-V392 HydrophobicContact CE3-CG2 4.48Å; W389-V392 HydrophobicContact CZ3-CB 4.46Å; W389-V392 HydrophobicContact CZ3-CG1 4.02Å; W389-V392 PolarHBondContact O-N 3.09Å; W389-G393 PolarHBondContact O-N 2.9Å; W389-F423 HydrophobicContact CE3-CZ 4.26Å; W389-F423 HydrophobicContact CZ3-CZ 4.01Å; W389-L430 HydrophobicContact CD2-CD1 4.49Å; W389-L430 HydrophobicContact CG-CD1 4.29Å
390	F	92.6	Very high	92.5	Very high	94 Å²	94	16.2 Å²	16.2	41%	0.412	8%	0.079	S	C	.	.	H	α-helix	trans	-57.6	-50.1	171.1	175.6	-99.2	0	0	0	111.6	F386 Y388 G393 L394 V431	F386-F390 WeakPolarHBondContact O-CB 3.35Å; F386-F390 PolarHBondContact O-N 2.89Å; F386-F390 VanDerWaalsContact O-N 3.11Å; Y388-F390 VanDerWaalsContact C-N 3.35Å; Y388-F390 PolarHBondContact O-N 3.29Å; F390-G393 PolarHBondContact O-N 3.35Å; F390-L394 PolarHBondContact O-N 3.36Å; F390-V431 HydrophobicContact CB-CG2 4.06Å; F390-V431 HydrophobicContact CD2-CG1 4.27Å; F390-V431 HydrophobicContact CD2-CG2 4.33Å
391	F	93	Very high	92.6	Very high	4 Å²	4	19.7 Å²	19.7	2%	0.018	9%	0.092	C	C	.	.	H	α-helix	trans	-75	-29.8	-178.9	-78.7	-62.5	0	0	0	114.2	I106 I117 R118 T121 I126 S387 Y388 L394 S395	I106-F391 HydrophobicContact CD1-CD1 4.1Å; I117-F391 HydrophobicContact CG2-CE1 4.39Å; I117-F391 HydrophobicContact CG2-CZ 3.99Å; R118-F391 HydrophobicContact CB-CD1 3.78Å; R118-F391 HydrophobicContact CB-CE1 3.8Å; R118-F391 HydrophobicContact CB-CG 4.43Å; R118-F391 HydrophobicContact CB-CZ 4.49Å; R118-F391 HydrophobicContact CG-CD1 4.17Å; R118-F391 HydrophobicContact CG-CG 4.42Å; T121-F391 VanDerWaalsContact CB-CE2 3.45Å; T121-F391 HydrophobicContact CG2-CD2 4.37Å; T121-F391 HydrophobicContact CG2-CE2 3.63Å; T121-F391 WeakPolarHBondContact OG1-CE2 3.4Å; I126-F391 HydrophobicContact CD1-CD2 4.46Å; S387-F391 WeakPolarHBondContact O-CD2 3.3Å; S387-F391 PolarHBondContact O-N 2.99Å; Y388-F391 PolarHBondContact O-N 3.25Å; F391-L394 HydrophobicContact CD1-CD2 4.12Å; F391-L394 HydrophobicContact CE1-CD2 4.35Å; F391-L394 PolarHBondContact O-N 2.93Å; F391-S395 PolarHBondContact O-N 3.1Å; F391-S395 PolarHBondContact O-OG 3.1Å
392	V	93	Very high	92.6	Very high	1 Å²	1	20 Å²	20	1%	0.006	9%	0.094	C	C	.	.	H	α-helix	trans	-65.3	-45.2	171.4	173.1	0	0	0	0	109.8	Y89 W241 Y388 W389 L394 S395 I396 F423	Y89-V392 HydrophobicContact CE2-CG1 3.75Å; Y89-V392 WeakPolarHBondContact OH-CA 3.44Å; W241-V392 HydrophobicContact CH2-CG1 4.06Å; W241-V392 HydrophobicContact CZ2-CG1 4.27Å; Y388-V392 HydrophobicContact CD1-CG2 4.05Å; Y388-V392 HydrophobicContact CD2-CG2 4.41Å; Y388-V392 HydrophobicContact CE1-CG2 3.73Å; Y388-V392 HydrophobicContact CE2-CG2 4.11Å; Y388-V392 HydrophobicContact CG-CG2 4.38Å; Y388-V392 VanDerWaalsContact O-CG2 3.27Å; Y388-V392 WeakPolarHBondContact O-CG2 3.39Å; Y388-V392 PolarHBondContact O-N 3.04Å; W389-V392 HydrophobicContact CE3-CB 4.12Å; W389-V392 HydrophobicContact CE3-CG1 4.08Å; W389-V392 HydrophobicContact CE3-CG2 4.48Å; W389-V392 HydrophobicContact CZ3-CB 4.46Å; W389-V392 HydrophobicContact CZ3-CG1 4.02Å; W389-V392 PolarHBondContact O-N 3.09Å; V392-L394 VanDerWaalsContact C-N 3.35Å; V392-L394 PolarHBondContact O-N 2.79Å; V392-S395 WeakPolarHBondContact O-CB 3.18Å; V392-S395 PolarHBondContact O-N 3.24Å; V392-I396 HydrophobicContact CG1-CD1 4.4Å; V392-I396 PolarHBondContact O-N 3.47Å; V392-I396 VanDerWaalsContact O-N 3.16Å; V392-F423 HydrophobicContact CG1-CE1 3.83Å; V392-F423 HydrophobicContact CG1-CZ 3.72Å
393	G	94.6	Very high	92.7	Very high	4 Å²	4	20.8 Å²	20.8	4%	0.041	10%	0.096	C	C	.	.	H	α-helix	trans	-58.9	-43.8	172	0	0	0	0	0	112.3	W389 F390 S395 I396 L397	W389-G393 PolarHBondContact O-N 2.9Å; F390-G393 PolarHBondContact O-N 3.35Å; G393-S395 VanDerWaalsContact C-N 3.33Å; G393-S395 PolarHBondContact O-N 2.87Å; G393-I396 PolarHBondContact O-N 2.93Å; G393-L397 PolarHBondContact O-N 2.82Å
394	L	94.6	Very high	92.9	Very high	25 Å²	25	29.1 Å²	29.1	13%	0.131	13%	0.127	C	C	.	.	H	α-helix	trans	-61.3	-40.5	176.1	-172.1	63	0	0	0	112.3	I106 F110 L114 F390 F391 V392 I396 L397 G398	I106-L394 HydrophobicContact CD1-CB 4.44Å; I106-L394 HydrophobicContact CD1-CD2 4.1Å; I106-L394 HydrophobicContact CD1-CG 4.34Å; I106-L394 HydrophobicContact CG1-CD2 4.5Å; I106-L394 HydrophobicContact CG1-CG 4.45Å; I106-L394 HydrophobicContact CG2-CD2 4.47Å; F110-L394 HydrophobicContact CD2-CD1 4.38Å; F110-L394 HydrophobicContact CD2-CG 4.39Å; F110-L394 HydrophobicContact CE2-CD1 3.84Å; F110-L394 HydrophobicContact CE2-CG 4.03Å; F110-L394 WeakPolarHBondContact CE2-O 3.41Å; F110-L394 HydrophobicContact CZ-CD1 4.16Å; L114-L394 HydrophobicContact CD1-CD2 4.44Å; L114-L394 HydrophobicContact CD2-CD2 4.47Å; F390-L394 PolarHBondContact O-N 3.36Å; F391-L394 HydrophobicContact CD1-CD2 4.12Å; F391-L394 HydrophobicContact CE1-CD2 4.35Å; F391-L394 PolarHBondContact O-N 2.93Å; V392-L394 VanDerWaalsContact C-N 3.35Å; V392-L394 PolarHBondContact O-N 2.79Å; L394-I396 VanDerWaalsContact C-N 3.33Å; L394-I396 PolarHBondContact O-N 3.36Å; L394-L397 WeakPolarHBondContact O-CB 3.46Å; L394-L397 PolarHBondContact O-N 3.21Å; L394-G398 PolarHBondContact O-N 3.07Å
395	S	94.1	Very high	93	Very high	1 Å²	1	34.4 Å²	34.4	1%	0.007	15%	0.151	C	C	.	.	H	α-helix	trans	-61.5	-41.8	176.8	-55	0	0	0	0	111.8	Y89 F391 V392 G393 G398 Q399	Y89-S395 VanDerWaalsContact OH-CB 3.3Å; Y89-S395 WeakPolarHBondContact OH-CB 3.26Å; Y89-S395 PolarHBondContact OH-OG 2.81Å; F391-S395 PolarHBondContact O-N 3.1Å; F391-S395 PolarHBondContact O-OG 3.1Å; V392-S395 WeakPolarHBondContact O-CB 3.18Å; V392-S395 PolarHBondContact O-N 3.24Å; G393-S395 VanDerWaalsContact C-N 3.33Å; G393-S395 PolarHBondContact O-N 2.87Å; S395-G398 WeakPolarHBondContact O-CA 3.41Å; S395-G398 PolarHBondContact O-N 3.39Å; S395-G398 VanDerWaalsContact O-N 3.13Å; S395-Q399 PolarHBondContact O-N 3.27Å; S395-Q399 VanDerWaalsContact O-N 3.08Å
396	I	94.4	Very high	93	Very high	0 Å²	0	38.1 Å²	38.1	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-75.5	-32.8	179.2	-69.3	167.6	0	0	0	111.7	C88 Y89 V392 G393 L394 G398 Q399 L400 P420 F423	C88-I396 HydrophobicContact CB-CD1 3.7Å; C88-I396 HydrophobicContact CB-CG1 3.86Å; C88-I396 HydrophobicContact CB-CG2 4.32Å; Y89-I396 HydrophobicContact CD2-CD1 3.92Å; Y89-I396 HydrophobicContact CD2-CG1 4.03Å; Y89-I396 HydrophobicContact CE2-CD1 3.86Å; Y89-I396 HydrophobicContact CE2-CG1 3.86Å; V392-I396 HydrophobicContact CG1-CD1 4.4Å; V392-I396 PolarHBondContact O-N 3.47Å; V392-I396 VanDerWaalsContact O-N 3.16Å; G393-I396 PolarHBondContact O-N 2.93Å; L394-I396 VanDerWaalsContact C-N 3.33Å; L394-I396 PolarHBondContact O-N 3.36Å; I396-G398 PolarHBondContact O-N 3.15Å; I396-Q399 WeakPolarHBondContact O-CB 3.26Å; I396-Q399 PolarHBondContact O-N 3.28Å; I396-Q399 VanDerWaalsContact O-N 3.08Å; I396-L400 PolarHBondContact O-N 3.05Å; I396-L400 VanDerWaalsContact O-N 3.15Å; I396-P420 HydrophobicContact CG2-CB 3.6Å; I396-F423 HydrophobicContact CB-CD1 4.29Å; I396-F423 HydrophobicContact CD1-CD1 3.22Å; I396-F423 HydrophobicContact CD1-CD2 4.48Å; I396-F423 HydrophobicContact CD1-CE1 3.26Å; I396-F423 HydrophobicContact CD1-CG 3.87Å; I396-F423 HydrophobicContact CD1-CZ 3.95Å; I396-F423 HydrophobicContact CG1-CD1 4.32Å; I396-F423 HydrophobicContact CG1-CE1 4.47Å; I396-F423 HydrophobicContact CG2-CD1 4.27Å
397	L	95.3	Very high	92.9	Very high	82 Å²	82	41 Å²	41	43%	0.429	19%	0.188	S	C	.	.	H	α-helix	trans	-59.3	-38	164.9	-81.2	168	0	0	0	111.1	F110 G393 L394 Q399 L400 Y401 C424	F110-L397 HydrophobicContact CZ-CB 4.45Å; G393-L397 PolarHBondContact O-N 2.82Å; L394-L397 WeakPolarHBondContact O-CB 3.46Å; L394-L397 PolarHBondContact O-N 3.21Å; L397-Q399 VanDerWaalsContact C-N 3.3Å; L397-Q399 PolarHBondContact O-N 2.94Å; L397-L400 PolarHBondContact O-N 3.27Å; L397-Y401 WeakPolarHBondContact O-CB 3.35Å; L397-Y401 PolarHBondContact O-N 3.48Å; L397-C424 HydrophobicContact CD2-CB 4.48Å
398	G	93.2	Very high	92.8	Very high	1 Å²	1	48.2 Å²	48.2	1%	0.01	23%	0.226	C	C	.	.	H	α-helix	trans	-58.5	-39.5	171.3	0	0	0	0	0	112.7	L394 S395 I396 Y401 L402	L394-G398 PolarHBondContact O-N 3.07Å; S395-G398 WeakPolarHBondContact O-CA 3.41Å; S395-G398 PolarHBondContact O-N 3.39Å; S395-G398 VanDerWaalsContact O-N 3.13Å; I396-G398 PolarHBondContact O-N 3.15Å; G398-Y401 PolarHBondContact O-N 3.22Å; G398-L402 WeakPolarHBondContact O-CB 3.3Å; G398-L402 VanDerWaalsContact O-CG 3.28Å; G398-L402 WeakPolarHBondContact O-CG 3.45Å; G398-L402 PolarHBondContact O-N 2.68Å
399	Q	93.4	Very high	92.7	Very high	4 Å²	4	50.9 Å²	50.9	2%	0.019	24%	0.236	C	C	.	.	H	α-helix	trans	-59.6	-47.2	173	-167.9	-167.9	-19.6	0	0	111.9	C88 E91 L92 S395 I396 L397 Y401 L402 R403	C88-Q399 PolarHBondContact O-OE1 3.37Å; E91-Q399 PolarHBondContact OE1-NE2 2.81Å; E91-Q399 PolarHBondContact OE2-NE2 3.38Å; L92-Q399 HydrophobicContact CD1-CB 4.18Å; L92-Q399 HydrophobicContact CD2-CB 3.72Å; L92-Q399 HydrophobicContact CD2-CG 3.91Å; L92-Q399 HydrophobicContact CG-CB 4Å; L92-Q399 HydrophobicContact CG-CG 4.05Å; S395-Q399 PolarHBondContact O-N 3.27Å; S395-Q399 VanDerWaalsContact O-N 3.08Å; I396-Q399 WeakPolarHBondContact O-CB 3.26Å; I396-Q399 PolarHBondContact O-N 3.28Å; I396-Q399 VanDerWaalsContact O-N 3.08Å; L397-Q399 VanDerWaalsContact C-N 3.3Å; L397-Q399 PolarHBondContact O-N 2.94Å; Q399-Y401 VanDerWaalsContact C-N 3.35Å; Q399-L402 PolarHBondContact O-N 3.07Å; Q399-R403 WeakPolarHBondContact O-CG 3.43Å; Q399-R403 PolarHBondContact O-N 3.16Å
400	L	94	Very high	92.5	Very high	40 Å²	40	59.2 Å²	59.2	21%	0.209	28%	0.275	C	S	.	.	H	α-helix	trans	-63.4	-41.9	177	-68.7	175.7	0	0	0	111.5	I396 L397 R403 W404 L417 P420 I421	I396-L400 PolarHBondContact O-N 3.05Å; I396-L400 VanDerWaalsContact O-N 3.15Å; L397-L400 PolarHBondContact O-N 3.27Å; L400-R403 WeakPolarHBondContact O-CB 3.27Å; L400-R403 PolarHBondContact O-N 2.87Å; L400-W404 PolarHBondContact O-N 2.84Å; L400-L417 HydrophobicContact CD2-CD2 3.74Å; L400-P420 HydrophobicContact CD1-CB 4.49Å; L400-P420 HydrophobicContact CD2-CB 3.96Å; L400-P420 HydrophobicContact CD2-CG 3.77Å; L400-P420 HydrophobicContact CG-CB 4.13Å; L400-P420 HydrophobicContact CG-CG 4.48Å; L400-I421 HydrophobicContact CD1-CG1 4.27Å; L400-I421 HydrophobicContact CD2-CG1 4.3Å
401	Y	94.3	Very high	92.4	Very high	73 Å²	73	56.7 Å²	56.7	29%	0.286	26%	0.263	S	S	.	.	H	α-helix	trans	-61.7	-45.8	176.1	177.4	-103.7	0	0	0	112.2	A109 F110 L397 G398 Q399 R403 W404 K405	A109-Y401 HydrophobicContact CB-CD1 4.5Å; A109-Y401 WeakPolarHBondContact O-CD1 3.39Å; A109-Y401 WeakPolarHBondContact O-CE1 3.45Å; F110-Y401 HydrophobicContact CE1-CD1 4.48Å; F110-Y401 HydrophobicContact CE1-CG 4.32Å; L397-Y401 WeakPolarHBondContact O-CB 3.35Å; L397-Y401 PolarHBondContact O-N 3.48Å; G398-Y401 PolarHBondContact O-N 3.22Å; Q399-Y401 VanDerWaalsContact C-N 3.35Å; Y401-R403 VanDerWaalsContact C-N 3.3Å; Y401-R403 PolarHBondContact O-N 3.19Å; Y401-W404 PolarHBondContact O-N 2.95Å; Y401-W404 VanDerWaalsContact O-N 3.15Å; Y401-K405 HydrophobicContact CE1-CB 4.44Å; Y401-K405 HydrophobicContact CE1-CD 3.6Å; Y401-K405 HydrophobicContact CE2-CD 4.28Å; Y401-K405 VanDerWaalsContact CZ-CD 3.43Å; Y401-K405 WeakPolarHBondContact O-CB 3.46Å; Y401-K405 PolarHBondContact O-N 2.82Å; Y401-K405 WeakPolarHBondContact OH-CD 3.44Å; Y401-K405 PolarHBondContact OH-NZ 3.32Å
402	L	92.3	Very high	92.2	Very high	8 Å²	8	59.4 Å²	59.4	4%	0.042	28%	0.281	C	S	.	.	H	α-helix	trans	-65.2	-33.6	177.3	-73.5	173.1	0	0	0	112.1	I96 A109 G398 Q399 W404 Q406 R411	I96-L402 HydrophobicContact CD1-CD1 3.94Å; A109-L402 HydrophobicContact CB-CD1 4.11Å; A109-L402 HydrophobicContact CB-CD2 4.5Å; A109-L402 HydrophobicContact CB-CG 4.07Å; G398-L402 WeakPolarHBondContact O-CB 3.3Å; G398-L402 VanDerWaalsContact O-CG 3.28Å; G398-L402 WeakPolarHBondContact O-CG 3.45Å; G398-L402 PolarHBondContact O-N 2.68Å; Q399-L402 PolarHBondContact O-N 3.07Å; L402-W404 VanDerWaalsContact C-N 3.29Å; L402-W404 PolarHBondContact O-N 2.74Å; L402-Q406 CarbonylContact O-C 3.57Å; L402-Q406 VanDerWaalsContact O-C 3.29Å; L402-Q406 WeakPolarHBondContact O-CA 3.27Å; L402-Q406 PolarHBondContact O-N 3.29Å; L402-Q406 VanDerWaalsContact O-O 3.05Å; L402-R411 PolarHBondContact O-NH2 2.94Å; L402-R411 VanDerWaalsContact O-NH2 3.11Å
403	R	91.4	Very high	91.9	Very high	31 Å²	31	61.2 Å²	61.2	12%	0.117	29%	0.29	C	S	.	.	H	α-helix	trans	-63	-35.6	172.6	-78.6	-177.5	171.5	-144.5	0.9	113.1	E91 Q399 L400 Y401 R411 L415 L417	E91-R403 IonicContact OE1-CZ 2.7Å; E91-R403 IonicContact OE1-NE 2.7Å; E91-R403 PolarHBondContact OE1-NE 3.08Å; E91-R403 IonicContact OE1-NH2 3.76Å; E91-R403 PolarHBondContact OE1-NH2 3.43Å; E91-R403 IonicContact OE2-CZ 2.84Å; E91-R403 IonicContact OE2-NH2 3.79Å; E91-R403 PolarHBondContact OE2-NH2 3.22Å; Q399-R403 WeakPolarHBondContact O-CG 3.43Å; Q399-R403 PolarHBondContact O-N 3.16Å; L400-R403 WeakPolarHBondContact O-CB 3.27Å; L400-R403 PolarHBondContact O-N 2.87Å; Y401-R403 VanDerWaalsContact C-N 3.3Å; Y401-R403 PolarHBondContact O-N 3.19Å; R403-R411 VanDerWaalsContact CA-NH2 3.31Å; R403-L415 VanDerWaalsContact CZ-O 3.32Å; R403-L415 PolarHBondContact NH1-O 2.91Å; R403-L415 PolarHBondContact NH2-O 3.33Å; R403-L417 VanDerWaalsContact NH1-CD2 3.31Å
404	W	92.1	Very high	91.6	Very high	208 Å²	208	68.2 Å²	68.2	79%	0.788	32%	0.32	S	S	*	.	H	α-helix	trans	-80.8	-45.3	178.6	-179.6	62.4	0	0	0	112.7	L400 Y401 L402	L400-W404 PolarHBondContact O-N 2.84Å; Y401-W404 PolarHBondContact O-N 2.95Å; Y401-W404 VanDerWaalsContact O-N 3.15Å; L402-W404 VanDerWaalsContact C-N 3.29Å; L402-W404 PolarHBondContact O-N 2.74Å
405	K	92.9	Very high	91.4	Very high	124 Å²	124	68.4 Å²	68.4	54%	0.539	32%	0.321	S	S	.	.	H	α-helix	trans	-81.4	-33.3	-174.9	-174.2	172.8	-179.4	-173.5	0	114.1	Y401	Y401-K405 HydrophobicContact CE1-CB 4.44Å; Y401-K405 HydrophobicContact CE1-CD 3.6Å; Y401-K405 HydrophobicContact CE2-CD 4.28Å; Y401-K405 VanDerWaalsContact CZ-CD 3.43Å; Y401-K405 WeakPolarHBondContact O-CB 3.46Å; Y401-K405 PolarHBondContact O-N 2.82Å; Y401-K405 WeakPolarHBondContact OH-CD 3.44Å; Y401-K405 PolarHBondContact OH-NZ 3.32Å
406	Q	92	Very high	91.3	Very high	77 Å²	77	71.3 Å²	71.3	36%	0.36	34%	0.341	S	S	.	.			trans	-128.3	72.8	-179	-66.3	-179.7	-6.1	0	0	109.3	L402 D408 R409 R411	L402-Q406 CarbonylContact O-C 3.57Å; L402-Q406 VanDerWaalsContact O-C 3.29Å; L402-Q406 WeakPolarHBondContact O-CA 3.27Å; L402-Q406 PolarHBondContact O-N 3.29Å; L402-Q406 VanDerWaalsContact O-O 3.05Å; Q406-D408 VanDerWaalsContact C-N 3.32Å; Q406-D408 PolarHBondContact O-N 3.49Å; Q406-R409 HydrophobicContact CB-CB 4.39Å; Q406-R409 VanDerWaalsContact OE1-NH1 3.15Å; Q406-R411 PolarHBondContact O-NH2 2.71Å
407	P	89.1	Confident	91.2	Very high	74 Å²	74	75.3 Å²	75.3	48%	0.481	36%	0.362	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.4	-35.8	-176.8	26.6	-33.5	0	0	0	112.3	R409 R411	P407-R409 VanDerWaalsContact C-N 3.31Å; P407-R409 PolarHBondContact O-N 3.38Å; P407-R411 PolarHBondContact O-NH1 3.45Å
408	D	89.4	Confident	91	Very high	154 Å²	154	76.5 Å²	76.5	82%	0.824	37%	0.367	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.6	0.8	-172.8	-54.2	-43.4	0	0	0	114.4	Q406 E410	Q406-D408 VanDerWaalsContact C-N 3.32Å; Q406-D408 PolarHBondContact O-N 3.49Å; D408-E410 PolarHBondContact O-N 3.35Å
409	R	89.6	Confident	90.9	Very high	64 Å²	64	80.4 Å²	80.4	24%	0.242	38%	0.382	C	S	.	.	S	Bend	trans	-62.8	132.4	175.8	-171.7	173.1	-175.8	140.7	1	109.5	T95 E108 Q406 P407 R411	T95-R409 HydrophobicContact CG2-CG 4.24Å; E108-R409 IonicContact OE1-CZ 3.47Å; E108-R409 IonicContact OE1-NH1 2.68Å; E108-R409 PolarHBondContact OE1-NH1 2.88Å; E108-R409 IonicContact OE1-NH2 3.13Å; E108-R409 PolarHBondContact OE1-NH2 3.47Å; E108-R409 VanDerWaalsContact OE1-NH2 3.13Å; Q406-R409 HydrophobicContact CB-CB 4.39Å; Q406-R409 VanDerWaalsContact OE1-NH1 3.15Å; P407-R409 VanDerWaalsContact C-N 3.31Å; P407-R409 PolarHBondContact O-N 3.38Å; R409-R411 PolarHBondContact O-N 3.46Å
410	E	88.3	Confident	90.9	Very high	174 Å²	174	80.2 Å²	80.2	81%	0.813	38%	0.381	S	S	*	.			trans	-59.2	126.4	175	-67.8	-172.1	166.5	0	0	110.3	D408	D408-E410 PolarHBondContact O-N 3.35Å
411	R	90.1	Very high	90.9	Very high	41 Å²	41	81.8 Å²	81.8	16%	0.155	39%	0.389	C	S	.	.			trans	-128.5	95.5	179.4	-69	-176.7	-175.6	108.9	10.8	108.5	T95 L402 R403 Q406 P407 R409 L413	T95-R411 HydrophobicContact CG2-CG 4.07Å; L402-R411 PolarHBondContact O-NH2 2.94Å; L402-R411 VanDerWaalsContact O-NH2 3.11Å; R403-R411 VanDerWaalsContact CA-NH2 3.31Å; Q406-R411 PolarHBondContact O-NH2 2.71Å; P407-R411 PolarHBondContact O-NH1 3.45Å; R409-R411 PolarHBondContact O-N 3.46Å; R411-L413 VanDerWaalsContact C-N 3.25Å; R411-L413 PolarHBondContact O-N 2.91Å
412	P	87.9	Confident	90.9	Very high	62 Å²	62	81.4 Å²	81.4	40%	0.403	39%	0.392	S	S	.	.	S	Bend	trans	-59	-38.3	-179.8	-25.6	34.7	0	0	0	112.7	E255	E255-P412 HydrophobicContact CB-CB 3.95Å; E255-P412 VanDerWaalsContact CD-CB 3.42Å; E255-P412 HydrophobicContact CG-CB 3.53Å; E255-P412 HydrophobicContact CG-CG 3.86Å; E255-P412 WeakPolarHBondContact OE1-CG 3.45Å
413	L	87.5	Confident	90.9	Very high	38 Å²	38	81 Å²	81	20%	0.199	39%	0.39	C	S	.	.	S	Bend	trans	-108.1	125	168.5	-171.6	77.8	0	0	0	109.3	A90 E91 T94 P259 R411 L415	A90-L413 HydrophobicContact CB-CD2 3.8Å; E91-L413 HydrophobicContact CB-CD2 4.19Å; E91-L413 WeakPolarHBondContact CG-O 3.45Å; T94-L413 HydrophobicContact CG2-CB 4.36Å; T94-L413 WeakPolarHBondContact OG1-CB 3.46Å; P259-L413 HydrophobicContact CB-CD1 4.32Å; P259-L413 HydrophobicContact CB-CD2 4.19Å; P259-L413 HydrophobicContact CG-CD1 4.08Å; P259-L413 HydrophobicContact CG-CD2 3.82Å; P259-L413 HydrophobicContact CG-CG 4.42Å; R411-L413 VanDerWaalsContact C-N 3.25Å; R411-L413 PolarHBondContact O-N 2.91Å; L413-L415 HydrophobicContact CD2-CG 4.49Å
414	K	88.1	Confident	91	Very high	152 Å²	152	80 Å²	80	66%	0.661	39%	0.387	S	S	*	.			trans	-127.1	107.6	175.8	-172.7	178.5	179.7	177.9	0	110.3
415	L	89.4	Confident	91.1	Very high	29 Å²	29	76.8 Å²	76.8	15%	0.152	38%	0.379	C	S	.	.			trans	-82	160	176.2	-65.1	170.4	0	0	0	111.9	L87 E91 R403 L413 Y419	L87-L415 HydrophobicContact CB-CD1 3.8Å; L87-L415 WeakPolarHBondContact O-CD1 3.3Å; E91-L415 HydrophobicContact CB-CD1 4.28Å; E91-L415 WeakPolarHBondContact OE2-CB 3.49Å; E91-L415 PolarHBondContact OE2-N 2.99Å; R403-L415 VanDerWaalsContact CZ-O 3.32Å; R403-L415 PolarHBondContact NH1-O 2.91Å; R403-L415 PolarHBondContact NH2-O 3.33Å; L413-L415 HydrophobicContact CD2-CG 4.49Å; L415-Y419 HydrophobicContact CB-CD2 4.44Å
416	S	92.6	Very high	91	Very high	62 Å²	62	74.1 Å²	74.1	43%	0.434	37%	0.37	S	S	.	.			trans	-61.7	143.8	167.4	-179.8	0	0	0	0	110	I418 Y419 P420	S416-I418 PolarHBondContact O-N 2.76Å; S416-I418 VanDerWaalsContact O-N 3.11Å; S416-Y419 PolarHBondContact O-N 2.92Å; S416-P420 VanDerWaalsContact O-CD 3.3Å; S416-P420 WeakPolarHBondContact O-CD 3.38Å
417	L	91.6	Very high	91	Very high	83 Å²	83	70.8 Å²	70.8	44%	0.435	36%	0.355	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.5	-19.9	177.6	-75.7	168.8	0	0	0	113.1	L400 R403 Y419 P420 I421	L400-L417 HydrophobicContact CD2-CD2 3.74Å; R403-L417 VanDerWaalsContact NH1-CD2 3.31Å; L417-Y419 VanDerWaalsContact C-N 3.3Å; L417-Y419 PolarHBondContact O-N 3.16Å; L417-P420 VanDerWaalsContact O-CD 3.29Å; L417-P420 WeakPolarHBondContact O-CD 3.49Å; L417-P420 WeakPolarHBondContact O-CG 3.48Å; L417-I421 HydrophobicContact CB-CD1 4.15Å; L417-I421 WeakPolarHBondContact O-CB 3.28Å; L417-I421 WeakPolarHBondContact O-CD1 3.37Å; L417-I421 WeakPolarHBondContact O-CG1 3.3Å; L417-I421 PolarHBondContact O-N 2.65Å
418	I	92.1	Very high	91.1	Very high	107 Å²	107	71.7 Å²	71.7	55%	0.549	36%	0.355	S	S	.	.	H	α-helix	trans	-58.3	-42.3	179.2	-62.5	172	0	0	0	111.1	S416 I421 I422	S416-I418 PolarHBondContact O-N 2.76Å; S416-I418 VanDerWaalsContact O-N 3.11Å; I418-I421 PolarHBondContact O-N 2.8Å; I418-I422 HydrophobicContact CG2-CD1 3.5Å; I418-I422 HydrophobicContact CG2-CG1 4.21Å; I418-I422 WeakPolarHBondContact O-CB 3.28Å; I418-I422 VanDerWaalsContact O-CG1 3.28Å; I418-I422 WeakPolarHBondContact O-CG1 3.45Å; I418-I422 PolarHBondContact O-N 3.31Å
419	Y	91.9	Very high	91.2	Very high	83 Å²	83	67.8 Å²	67.8	33%	0.325	33%	0.331	S	S	.	.	H	α-helix	trans	-60.6	-58.6	-178.2	-66.7	-85.6	0	0	0	113.2	F84 L87 L415 S416 L417 I421 I422 F423	F84-Y419 AromaticContact CD1-CD1 3.64Å; F84-Y419 HydrophobicContact CD1-CD1 3.64Å; F84-Y419 AromaticContact CD1-CE1 3.93Å; F84-Y419 HydrophobicContact CD1-CE1 3.93Å; F84-Y419 AromaticContact CE1-CD1 3.75Å; F84-Y419 HydrophobicContact CE1-CD1 3.75Å; F84-Y419 AromaticContact CE1-CE1 3.64Å; F84-Y419 HydrophobicContact CE1-CE1 3.64Å; F84-Y419 HydrophobicContact CG-CD1 4.25Å; F84-Y419 HydrophobicContact CZ-CD1 4.43Å; F84-Y419 HydrophobicContact CZ-CE1 4.42Å; L87-Y419 HydrophobicContact CD1-CE1 4.42Å; L415-Y419 HydrophobicContact CB-CD2 4.44Å; S416-Y419 PolarHBondContact O-N 2.92Å; L417-Y419 VanDerWaalsContact C-N 3.3Å; L417-Y419 PolarHBondContact O-N 3.16Å; Y419-I421 VanDerWaalsContact C-N 3.29Å; Y419-I421 PolarHBondContact O-N 3.3Å; Y419-I422 PolarHBondContact O-N 2.86Å; Y419-F423 WeakPolarHBondContact O-CB 3.44Å; Y419-F423 PolarHBondContact O-N 2.83Å
420	P	93.3	Very high	91.2	Very high	0 Å²	0	65 Å²	65	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-64.4	-32.3	179.4	24	-34	0	0	0	112.8	C88 I396 L400 S416 L417 F423 C424	C88-P420 VanDerWaalsContact SG-CA 3.59Å; I396-P420 HydrophobicContact CG2-CB 3.6Å; L400-P420 HydrophobicContact CD1-CB 4.49Å; L400-P420 HydrophobicContact CD2-CB 3.96Å; L400-P420 HydrophobicContact CD2-CG 3.77Å; L400-P420 HydrophobicContact CG-CB 4.13Å; L400-P420 HydrophobicContact CG-CG 4.48Å; S416-P420 VanDerWaalsContact O-CD 3.3Å; S416-P420 WeakPolarHBondContact O-CD 3.38Å; L417-P420 VanDerWaalsContact O-CD 3.29Å; L417-P420 WeakPolarHBondContact O-CD 3.49Å; L417-P420 WeakPolarHBondContact O-CG 3.48Å; P420-F423 PolarHBondContact O-N 3.46Å; P420-C424 WeakPolarHBondContact O-CB 3.13Å; P420-C424 PolarHBondContact O-N 3.23Å; P420-C424 PolarHBondContact O-SG 3.43Å
421	I	93.9	Very high	91.2	Very high	73 Å²	73	57.7 Å²	57.7	37%	0.374	29%	0.288	S	S	.	.	H	α-helix	trans	-65.5	-50.1	177.1	-69.3	169.5	0	0	0	110.8	L400 L417 I418 Y419 F423 C424 F425	L400-I421 HydrophobicContact CD1-CG1 4.27Å; L400-I421 HydrophobicContact CD2-CG1 4.3Å; L417-I421 HydrophobicContact CB-CD1 4.15Å; L417-I421 WeakPolarHBondContact O-CB 3.28Å; L417-I421 WeakPolarHBondContact O-CD1 3.37Å; L417-I421 WeakPolarHBondContact O-CG1 3.3Å; L417-I421 PolarHBondContact O-N 2.65Å; I418-I421 PolarHBondContact O-N 2.8Å; Y419-I421 VanDerWaalsContact C-N 3.29Å; Y419-I421 PolarHBondContact O-N 3.3Å; I421-F423 VanDerWaalsContact C-N 3.28Å; I421-F423 PolarHBondContact O-N 3.03Å; I421-C424 PolarHBondContact O-N 2.91Å; I421-F425 HydrophobicContact CG2-CD2 3.85Å; I421-F425 HydrophobicContact CG2-CE2 3.63Å; I421-F425 VanDerWaalsContact O-CD2 3.25Å; I421-F425 WeakPolarHBondContact O-CD2 3.45Å; I421-F425 PolarHBondContact O-N 3.2Å
422	I	93.6	Very high	91.2	Very high	66 Å²	66	59.4 Å²	59.4	34%	0.338	30%	0.303	S	S	.	.	H	α-helix	trans	-59	-43.9	177.1	-70	173.1	0	0	0	110.1	F84 I418 Y419 C424 F425 L426	F84-I422 HydrophobicContact CD2-CG2 4.02Å; F84-I422 HydrophobicContact CE2-CG2 3.96Å; I418-I422 HydrophobicContact CG2-CD1 3.5Å; I418-I422 HydrophobicContact CG2-CG1 4.21Å; I418-I422 WeakPolarHBondContact O-CB 3.28Å; I418-I422 VanDerWaalsContact O-CG1 3.28Å; I418-I422 WeakPolarHBondContact O-CG1 3.45Å; I418-I422 PolarHBondContact O-N 3.31Å; Y419-I422 PolarHBondContact O-N 2.86Å; I422-C424 VanDerWaalsContact C-N 3.34Å; I422-C424 PolarHBondContact O-N 2.85Å; I422-F425 PolarHBondContact O-N 3.28Å; I422-L426 HydrophobicContact CG2-CD1 3.77Å; I422-L426 HydrophobicContact CG2-CG 4.29Å; I422-L426 WeakPolarHBondContact O-CG 3.45Å; I422-L426 PolarHBondContact O-N 3.46Å
423	F	93.1	Very high	91.3	Very high	0 Å²	0	56.9 Å²	56.9	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-62.7	-39.4	178.5	-169.6	-86.1	0	0	0	112.6	F81 F84 W389 V392 I396 Y419 P420 I421 L426 T427	F81-F423 HydrophobicContact CD1-CE2 4.18Å; F81-F423 HydrophobicContact CD2-CD2 4.15Å; F81-F423 HydrophobicContact CD2-CE2 4.04Å; F81-F423 AromaticContact CE1-CE2 3.73Å; F81-F423 HydrophobicContact CE1-CE2 3.73Å; F81-F423 HydrophobicContact CE1-CZ 4.01Å; F81-F423 AromaticContact CE2-CD2 3.78Å; F81-F423 HydrophobicContact CE2-CD2 3.78Å; F81-F423 AromaticContact CE2-CE2 3.51Å; F81-F423 HydrophobicContact CE2-CE2 3.51Å; F81-F423 HydrophobicContact CE2-CG 4.48Å; F81-F423 HydrophobicContact CE2-CZ 4.01Å; F81-F423 HydrophobicContact CG-CE2 4.36Å; F81-F423 HydrophobicContact CZ-CD2 4.11Å; F81-F423 HydrophobicContact CZ-CE1 4.35Å; F81-F423 AromaticContact CZ-CE2 3.36Å; F81-F423 HydrophobicContact CZ-CE2 3.36Å; F81-F423 AromaticContact CZ-CZ 3.51Å; F81-F423 HydrophobicContact CZ-CZ 3.51Å; F84-F423 HydrophobicContact CB-CD2 4.19Å; W389-F423 HydrophobicContact CE3-CZ 4.26Å; W389-F423 HydrophobicContact CZ3-CZ 4.01Å; V392-F423 HydrophobicContact CG1-CE1 3.83Å; V392-F423 HydrophobicContact CG1-CZ 3.72Å; I396-F423 HydrophobicContact CB-CD1 4.29Å; I396-F423 HydrophobicContact CD1-CD1 3.22Å; I396-F423 HydrophobicContact CD1-CD2 4.48Å; I396-F423 HydrophobicContact CD1-CE1 3.26Å; I396-F423 HydrophobicContact CD1-CG 3.87Å; I396-F423 HydrophobicContact CD1-CZ 3.95Å; I396-F423 HydrophobicContact CG1-CD1 4.32Å; I396-F423 HydrophobicContact CG1-CE1 4.47Å; I396-F423 HydrophobicContact CG2-CD1 4.27Å; Y419-F423 WeakPolarHBondContact O-CB 3.44Å; Y419-F423 PolarHBondContact O-N 2.83Å; P420-F423 PolarHBondContact O-N 3.46Å; I421-F423 VanDerWaalsContact C-N 3.28Å; I421-F423 PolarHBondContact O-N 3.03Å; F423-L426 PolarHBondContact O-N 2.74Å; F423-T427 HydrophobicContact CD1-CG2 3.77Å; F423-T427 HydrophobicContact CE1-CG2 3.23Å; F423-T427 HydrophobicContact CZ-CG2 3.74Å; F423-T427 WeakPolarHBondContact O-CG2 3.46Å; F423-T427 PolarHBondContact O-N 3.26Å; F423-T427 PolarHBondContact O-OG1 3.48Å
424	C	93.4	Very high	91.2	Very high	10 Å²	10	55.1 Å²	55.1	7%	0.068	28%	0.277	C	S	.	.	H	α-helix	trans	-61.4	-43	174	-70.1	0	0	0	0	111.7	L397 P420 I421 I422 T427 I428	L397-C424 HydrophobicContact CD2-CB 4.48Å; P420-C424 WeakPolarHBondContact O-CB 3.13Å; P420-C424 PolarHBondContact O-N 3.23Å; P420-C424 PolarHBondContact O-SG 3.43Å; I421-C424 PolarHBondContact O-N 2.91Å; I422-C424 VanDerWaalsContact C-N 3.34Å; I422-C424 PolarHBondContact O-N 2.85Å; C424-T427 VanDerWaalsContact CA-OG1 3.31Å; C424-T427 WeakPolarHBondContact CA-OG1 3.4Å; C424-T427 PolarHBondContact O-N 3.32Å; C424-T427 PolarHBondContact O-OG1 3.05Å; C424-I428 VanDerWaalsContact O-CG1 3.24Å; C424-I428 WeakPolarHBondContact O-CG1 3.37Å; C424-I428 PolarHBondContact O-N 3.37Å
425	F	92.9	Very high	91.1	Very high	140 Å²	140	50.7 Å²	50.7	61%	0.614	26%	0.26	S	S	*	.	H	α-helix	trans	-63.6	-43.1	175.7	-80.1	-68.3	0	0	0	112.6	I421 I422 I428 F429	I421-F425 HydrophobicContact CG2-CD2 3.85Å; I421-F425 HydrophobicContact CG2-CE2 3.63Å; I421-F425 VanDerWaalsContact O-CD2 3.25Å; I421-F425 WeakPolarHBondContact O-CD2 3.45Å; I421-F425 PolarHBondContact O-N 3.2Å; I422-F425 PolarHBondContact O-N 3.28Å; F425-I428 PolarHBondContact O-N 3.22Å; F425-F429 PolarHBondContact O-N 3.3Å
426	L	91.6	Very high	91	Very high	67 Å²	67	55.3 Å²	55.3	35%	0.351	28%	0.277	S	S	.	.	H	α-helix	trans	-67.7	-36.3	178.6	-67.7	173.9	0	0	0	112	F81 I422 F423 F429 L430	F81-L426 HydrophobicContact CD2-CB 3.63Å; F81-L426 HydrophobicContact CD2-CD1 3.7Å; F81-L426 HydrophobicContact CD2-CG 4.27Å; F81-L426 HydrophobicContact CE2-CB 3.45Å; F81-L426 VanDerWaalsContact CE2-CB 3.45Å; F81-L426 HydrophobicContact CE2-CD1 4.35Å; I422-L426 HydrophobicContact CG2-CD1 3.77Å; I422-L426 HydrophobicContact CG2-CG 4.29Å; I422-L426 WeakPolarHBondContact O-CG 3.45Å; I422-L426 PolarHBondContact O-N 3.46Å; F423-L426 PolarHBondContact O-N 2.74Å; L426-F429 WeakPolarHBondContact O-CB 3.32Å; L426-F429 PolarHBondContact O-N 3.11Å; L426-L430 WeakPolarHBondContact O-CG 3.35Å; L426-L430 PolarHBondContact O-N 3.49Å
427	T	91.8	Very high	90.5	Very high	7 Å²	7	54.4 Å²	54.4	4%	0.043	27%	0.27	C	S	.	.	H	α-helix	trans	-68.9	-35.7	173	44.8	0	0	0	0	112.7	F81 F423 C424 F429 L430 V431	F81-T427 HydrophobicContact CE2-CG2 4.23Å; F81-T427 HydrophobicContact CZ-CG2 3.84Å; F423-T427 HydrophobicContact CD1-CG2 3.77Å; F423-T427 HydrophobicContact CE1-CG2 3.23Å; F423-T427 HydrophobicContact CZ-CG2 3.74Å; F423-T427 WeakPolarHBondContact O-CG2 3.46Å; F423-T427 PolarHBondContact O-N 3.26Å; F423-T427 PolarHBondContact O-OG1 3.48Å; C424-T427 VanDerWaalsContact CA-OG1 3.31Å; C424-T427 WeakPolarHBondContact CA-OG1 3.4Å; C424-T427 PolarHBondContact O-N 3.32Å; C424-T427 PolarHBondContact O-OG1 3.05Å; T427-F429 VanDerWaalsContact C-N 3.32Å; T427-F429 PolarHBondContact O-N 3.45Å; T427-L430 PolarHBondContact O-N 2.77Å; T427-V431 WeakPolarHBondContact O-CG2 3.31Å; T427-V431 PolarHBondContact O-N 2.85Å
428	I	92.1	Very high	90.1	Very high	94 Å²	94	51.9 Å²	51.9	48%	0.482	26%	0.257	S	S	.	.	H	α-helix	trans	-59.4	-45.9	171	-70.4	164.4	0	0	0	110.1	C424 F425 L430 V431 V432	C424-I428 VanDerWaalsContact O-CG1 3.24Å; C424-I428 WeakPolarHBondContact O-CG1 3.37Å; C424-I428 PolarHBondContact O-N 3.37Å; F425-I428 PolarHBondContact O-N 3.22Å; I428-L430 VanDerWaalsContact C-N 3.33Å; I428-L430 PolarHBondContact O-N 3.42Å; I428-V431 PolarHBondContact O-N 3.49Å; I428-V432 HydrophobicContact CG2-CG2 3.83Å; I428-V432 VanDerWaalsContact O-CB 3.3Å; I428-V432 WeakPolarHBondContact O-CB 3.5Å; I428-V432 VanDerWaalsContact O-CG2 3.27Å; I428-V432 WeakPolarHBondContact O-CG2 3.19Å; I428-V432 PolarHBondContact O-N 3.49Å
429	F	91	Very high	89.9	Confident	71 Å²	71	49.8 Å²	49.8	31%	0.311	25%	0.249	S	C	.	.	H	α-helix	trans	-56.6	-48.1	174.5	172.3	-93.1	0	0	0	111.5	A228 L231 F425 L426 T427 V431 V433	A228-F429 HydrophobicContact CB-CE1 4.04Å; A228-F429 HydrophobicContact CB-CZ 4.26Å; L231-F429 HydrophobicContact CD1-CE1 4.07Å; F425-F429 PolarHBondContact O-N 3.3Å; L426-F429 WeakPolarHBondContact O-CB 3.32Å; L426-F429 PolarHBondContact O-N 3.11Å; T427-F429 VanDerWaalsContact C-N 3.32Å; T427-F429 PolarHBondContact O-N 3.45Å; F429-V431 PolarHBondContact O-N 3.31Å; F429-V433 HydrophobicContact CD2-CG2 3.64Å; F429-V433 HydrophobicContact CE2-CB 4.49Å; F429-V433 HydrophobicContact CE2-CG2 3.55Å; F429-V433 HydrophobicContact CG-CG2 4.29Å; F429-V433 HydrophobicContact CZ-CG2 4.11Å; F429-V433 WeakPolarHBondContact O-CB 3.34Å; F429-V433 WeakPolarHBondContact O-CG2 3.26Å; F429-V433 PolarHBondContact O-N 3.4Å
430	L	88.9	Confident	89.7	Confident	5 Å²	5	51.7 Å²	51.7	3%	0.026	26%	0.264	C	S	.	.	H	α-helix	trans	-64.9	-22.6	179.2	-72.3	177.4	0	0	0	113.8	F81 L231 Y232 L235 W389 L426 T427 I428 P434	F81-L430 HydrophobicContact CE1-CD1 3.83Å; F81-L430 HydrophobicContact CE2-CD1 4.01Å; F81-L430 HydrophobicContact CZ-CD1 3.47Å; F81-L430 VanDerWaalsContact CZ-CD1 3.47Å; L231-L430 HydrophobicContact CB-CD2 4.05Å; L231-L430 HydrophobicContact CD1-CD2 4.35Å; Y232-L430 HydrophobicContact CD1-CD2 4.04Å; Y232-L430 HydrophobicContact CE1-CB 4.06Å; Y232-L430 HydrophobicContact CE1-CD2 3.95Å; Y232-L430 VanDerWaalsContact CE1-O 3.29Å; Y232-L430 WeakPolarHBondContact CE1-O 3.28Å; Y232-L430 VanDerWaalsContact CZ-O 3.24Å; Y232-L430 PolarHBondContact OH-O 2.87Å; L235-L430 HydrophobicContact CD1-CD1 3.48Å; L235-L430 VanDerWaalsContact CD1-CD1 3.48Å; L235-L430 HydrophobicContact CD1-CD2 4.12Å; L235-L430 HydrophobicContact CD1-CG 4.47Å; W389-L430 HydrophobicContact CD2-CD1 4.49Å; W389-L430 HydrophobicContact CG-CD1 4.29Å; L426-L430 WeakPolarHBondContact O-CG 3.35Å; L426-L430 PolarHBondContact O-N 3.49Å; T427-L430 PolarHBondContact O-N 2.77Å; I428-L430 VanDerWaalsContact C-N 3.33Å; I428-L430 PolarHBondContact O-N 3.42Å; L430-P434 WeakPolarHBondContact O-CD 3.41Å; L430-P434 VanDerWaalsContact O-CG 3.3Å; L430-P434 WeakPolarHBondContact O-CG 3.37Å
431	V	89.3	Confident	89.2	Confident	22 Å²	22	52.6 Å²	52.6	13%	0.133	27%	0.269	C	S	.	.	H	α-helix	trans	-94	-42.1	177.5	172.4	0	0	0	0	111.3	F386 F390 T427 I428 F429 L435	F386-V431 HydrophobicContact CE2-CG1 3.82Å; F386-V431 HydrophobicContact CZ-CG1 4.16Å; F390-V431 HydrophobicContact CB-CG2 4.06Å; F390-V431 HydrophobicContact CD2-CG1 4.27Å; F390-V431 HydrophobicContact CD2-CG2 4.33Å; T427-V431 WeakPolarHBondContact O-CG2 3.31Å; T427-V431 PolarHBondContact O-N 2.85Å; I428-V431 PolarHBondContact O-N 3.49Å; F429-V431 PolarHBondContact O-N 3.31Å; V431-L435 WeakPolarHBondContact O-CG 3.43Å
432	V	90	Very high	88.8	Confident	76 Å²	76	49.3 Å²	49.3	46%	0.461	25%	0.252	S	S	.	.	H	α-helix	trans	-74.9	-40.1	-173.9	174.1	0	0	0	0	111.9	I428 L435	I428-V432 HydrophobicContact CG2-CG2 3.83Å; I428-V432 VanDerWaalsContact O-CB 3.3Å; I428-V432 WeakPolarHBondContact O-CB 3.5Å; I428-V432 VanDerWaalsContact O-CG2 3.27Å; I428-V432 WeakPolarHBondContact O-CG2 3.19Å; I428-V432 PolarHBondContact O-N 3.49Å; V432-L435 WeakPolarHBondContact O-CB 3.47Å; V432-L435 PolarHBondContact O-N 2.92Å
433	V	88.8	Confident	88.6	Confident	10 Å²	10	50.9 Å²	50.9	6%	0.061	26%	0.261	C	S	.	.	H	α-helix	trans	-65.7	-45.1	-176.7	168.4	0	0	0	0	112.9	A228 F429 L435 Y436 S437	A228-V433 HydrophobicContact CB-CB 3.94Å; A228-V433 HydrophobicContact CB-CG1 3.38Å; F429-V433 HydrophobicContact CD2-CG2 3.64Å; F429-V433 HydrophobicContact CE2-CB 4.49Å; F429-V433 HydrophobicContact CE2-CG2 3.55Å; F429-V433 HydrophobicContact CG-CG2 4.29Å; F429-V433 HydrophobicContact CZ-CG2 4.11Å; F429-V433 WeakPolarHBondContact O-CB 3.34Å; F429-V433 WeakPolarHBondContact O-CG2 3.26Å; F429-V433 PolarHBondContact O-N 3.4Å; V433-L435 PolarHBondContact O-N 3.31Å; V433-Y436 HydrophobicContact CB-CE1 4.02Å; V433-Y436 HydrophobicContact CG1-CE1 4.11Å; V433-Y436 HydrophobicContact CG1-CE2 4.24Å; V433-Y436 VanDerWaalsContact CG1-OH 3.31Å; V433-Y436 WeakPolarHBondContact CG1-OH 3.29Å; V433-Y436 HydrophobicContact CG2-CE1 3.98Å; V433-Y436 WeakPolarHBondContact O-CD1 3.39Å; V433-Y436 WeakPolarHBondContact O-CE1 3.26Å; V433-Y436 PolarHBondContact O-N 2.95Å; V433-S437 PolarHBondContact O-N 2.96Å; V433-S437 VanDerWaalsContact O-N 3.13Å; V433-S437 PolarHBondContact O-OG 2.86Å
434	P	85.7	Confident	88.3	Confident	1 Å²	1	54.3 Å²	54.3	1%	0.006	28%	0.278	C	S	.	.	H	α-helix	trans	-67.5	-21.5	177.5	-29.5	44.1	0	0	0	113.9	A228 Y232 L430 Y436 S437 D438 S442	A228-P434 HydrophobicContact CB-CG 4.23Å; Y232-P434 HydrophobicContact CE1-CG 4.07Å; Y232-P434 HydrophobicContact CE2-CB 4.07Å; Y232-P434 HydrophobicContact CE2-CG 3.85Å; Y232-P434 WeakPolarHBondContact OH-CG 3.27Å; L430-P434 WeakPolarHBondContact O-CD 3.41Å; L430-P434 VanDerWaalsContact O-CG 3.3Å; L430-P434 WeakPolarHBondContact O-CG 3.37Å; P434-Y436 PolarHBondContact O-N 3.35Å; P434-S437 PolarHBondContact O-N 3.07Å; P434-D438 CarbonylContact O-C 3.52Å; P434-D438 VanDerWaalsContact O-C 3.32Å; P434-D438 WeakPolarHBondContact O-CA 3.5Å; P434-D438 PolarHBondContact O-N 3.2Å; P434-S442 PolarHBondContact O-OG 3.37Å
435	L	87	Confident	87.9	Confident	58 Å²	58	54 Å²	54	30%	0.304	28%	0.277	S	S	.	.	H	α-helix	trans	-60.6	-30.4	174.7	-78.6	168.5	0	0	0	113.4	F386 V431 V432 V433 T439 I446	F386-L435 HydrophobicContact CE2-CD2 4.26Å; F386-L435 HydrophobicContact CE2-CG 4.21Å; F386-L435 HydrophobicContact CZ-CD2 4.33Å; V431-L435 WeakPolarHBondContact O-CG 3.43Å; V432-L435 WeakPolarHBondContact O-CB 3.47Å; V432-L435 PolarHBondContact O-N 2.92Å; V433-L435 PolarHBondContact O-N 3.31Å; L435-T439 VanDerWaalsContact O-CA 3.28Å; L435-T439 WeakPolarHBondContact O-CA 3.31Å; L435-T439 VanDerWaalsContact O-CB 3.25Å; L435-T439 WeakPolarHBondContact O-CB 3.24Å; L435-T439 WeakPolarHBondContact O-CG2 3.21Å; L435-T439 PolarHBondContact O-OG1 3.02Å; L435-I446 HydrophobicContact CD2-CD1 3.72Å
436	Y	86.1	Confident	87.7	Confident	127 Å²	127	50 Å²	50	50%	0.498	26%	0.262	S	S	.	.	H	α-helix	trans	-98.9	-25.5	173.6	65.8	-104.1	0	0	0	113.2	V433 P434 T439	V433-Y436 HydrophobicContact CB-CE1 4.02Å; V433-Y436 HydrophobicContact CG1-CE1 4.11Å; V433-Y436 HydrophobicContact CG1-CE2 4.24Å; V433-Y436 VanDerWaalsContact CG1-OH 3.31Å; V433-Y436 WeakPolarHBondContact CG1-OH 3.29Å; V433-Y436 HydrophobicContact CG2-CE1 3.98Å; V433-Y436 WeakPolarHBondContact O-CD1 3.39Å; V433-Y436 WeakPolarHBondContact O-CE1 3.26Å; V433-Y436 PolarHBondContact O-N 2.95Å; P434-Y436 PolarHBondContact O-N 3.35Å; Y436-T439 PolarHBondContact O-OG1 3.45Å
437	S	83.3	Confident	87.7	Confident	43 Å²	43	48.8 Å²	48.8	30%	0.301	27%	0.265	S	S	.	.	H	α-helix	trans	-84.4	-33.7	-176.7	-50	0	0	0	0	112.9	G225 V433 P434	G225-S437 WeakPolarHBondContact CA-OG 3.42Å; V433-S437 PolarHBondContact O-N 2.96Å; V433-S437 VanDerWaalsContact O-N 3.13Å; V433-S437 PolarHBondContact O-OG 2.86Å; P434-S437 PolarHBondContact O-N 3.07Å
438	D	83.2	Confident	87.6	Confident	30 Å²	30	50.4 Å²	50.4	16%	0.16	27%	0.273	C	S	.	.	S	Bend	trans	-137.7	52.3	-179.7	-166	7.6	0	0	0	110.6	L229 N382 P434 I440 N441 S442	L229-D438 HydrophobicContact CD2-CB 4.38Å; N382-D438 PolarHBondContact ND2-OD2 3.42Å; P434-D438 CarbonylContact O-C 3.52Å; P434-D438 VanDerWaalsContact O-C 3.32Å; P434-D438 WeakPolarHBondContact O-CA 3.5Å; P434-D438 PolarHBondContact O-N 3.2Å; D438-I440 VanDerWaalsContact C-N 3.33Å; D438-I440 PolarHBondContact O-N 3.23Å; D438-N441 PolarHBondContact O-N 3.13Å; D438-N441 VanDerWaalsContact O-N 3.16Å; D438-N441 WeakPolarHBondContact OD1-CB 3.28Å; D438-N441 VanDerWaalsContact OD1-CG 3.32Å; D438-N441 PolarHBondContact OD1-ND2 3.25Å; D438-N441 WeakPolarHBondContact OD2-CB 3.44Å; D438-N441 PolarHBondContact OD2-ND2 2.88Å; D438-S442 PolarHBondContact O-N 3.42Å; D438-S442 VanDerWaalsContact O-N 3.07Å; D438-S442 PolarHBondContact O-OG 2.92Å
439	T	87	Confident	87.5	Confident	62 Å²	62	46.7 Å²	46.7	38%	0.38	26%	0.256	S	S	.	.	H	α-helix	trans	-54.1	-43.6	-168.3	-52.6	0	0	0	0	113.7	L435 Y436 N441 S442 L443	L435-T439 VanDerWaalsContact O-CA 3.28Å; L435-T439 WeakPolarHBondContact O-CA 3.31Å; L435-T439 VanDerWaalsContact O-CB 3.25Å; L435-T439 WeakPolarHBondContact O-CB 3.24Å; L435-T439 WeakPolarHBondContact O-CG2 3.21Å; L435-T439 PolarHBondContact O-OG1 3.02Å; Y436-T439 PolarHBondContact O-OG1 3.45Å; T439-N441 PolarHBondContact O-N 3Å; T439-S442 PolarHBondContact O-N 3.47Å; T439-L443 HydrophobicContact CG2-CD1 3.74Å; T439-L443 HydrophobicContact CG2-CG 4.14Å; T439-L443 VanDerWaalsContact O-CB 3.29Å; T439-L443 WeakPolarHBondContact O-CB 3.35Å; T439-L443 WeakPolarHBondContact O-CG 3.47Å; T439-L443 PolarHBondContact O-N 3.45Å
440	I	87.3	Confident	87.6	Confident	124 Å²	124	48.3 Å²	48.3	64%	0.636	27%	0.267	S	S	*	.	H	α-helix	trans	-63.1	-47.4	-177.2	-63.2	175.1	0	0	0	109.7	D438 L443 I444	D438-I440 VanDerWaalsContact C-N 3.33Å; D438-I440 PolarHBondContact O-N 3.23Å; I440-L443 PolarHBondContact O-N 3.16Å; I440-I444 HydrophobicContact CG2-CD1 3.93Å; I440-I444 VanDerWaalsContact O-CG1 3.29Å; I440-I444 WeakPolarHBondContact O-CG1 3.47Å; I440-I444 PolarHBondContact O-N 3.08Å
441	N	83.8	Confident	87.8	Confident	18 Å²	18	50.3 Å²	50.3	10%	0.096	28%	0.282	C	S	.	.	H	α-helix	trans	-68.4	-40.5	-176.3	-66.5	-24.7	0	0	0	111.3	Y383 D438 T439 I444 G445	Y383-N441 HydrophobicContact CD1-CB 3.96Å; Y383-N441 VanDerWaalsContact CE1-CA 3.48Å; Y383-N441 HydrophobicContact CE1-CB 3.47Å; Y383-N441 VanDerWaalsContact CE1-CB 3.47Å; Y383-N441 WeakPolarHBondContact CE1-O 3.23Å; Y383-N441 PolarHBondContact OH-OD1 2.95Å; D438-N441 PolarHBondContact O-N 3.13Å; D438-N441 VanDerWaalsContact O-N 3.16Å; D438-N441 WeakPolarHBondContact OD1-CB 3.28Å; D438-N441 VanDerWaalsContact OD1-CG 3.32Å; D438-N441 PolarHBondContact OD1-ND2 3.25Å; D438-N441 WeakPolarHBondContact OD2-CB 3.44Å; D438-N441 PolarHBondContact OD2-ND2 2.88Å; T439-N441 PolarHBondContact O-N 3Å; N441-I444 PolarHBondContact O-N 3.19Å; N441-G445 PolarHBondContact O-N 3.41Å; N441-G445 VanDerWaalsContact O-N 3.13Å
442	S	85.6	Confident	87.9	Confident	4 Å²	4	49.2 Å²	49.2	3%	0.028	28%	0.275	C	S	.	.	H	α-helix	trans	-63.9	-41.5	174.6	-61	0	0	0	0	112.6	P434 D438 T439 I444 G445 I446	P434-S442 PolarHBondContact O-OG 3.37Å; D438-S442 PolarHBondContact O-N 3.42Å; D438-S442 VanDerWaalsContact O-N 3.07Å; D438-S442 PolarHBondContact O-OG 2.92Å; T439-S442 PolarHBondContact O-N 3.47Å; S442-I444 PolarHBondContact O-N 2.92Å; S442-G445 PolarHBondContact O-N 3.46Å; S442-I446 WeakPolarHBondContact O-CG1 3.36Å; S442-I446 PolarHBondContact O-N 3.02Å
443	L	88.4	Confident	88	Confident	99 Å²	99	47.5 Å²	47.5	52%	0.518	27%	0.265	S	S	.	.	H	α-helix	trans	-65.4	-37.1	177.8	-75.7	176.7	0	0	0	112.5	T439 I440 G445 I446 G447	T439-L443 HydrophobicContact CG2-CD1 3.74Å; T439-L443 HydrophobicContact CG2-CG 4.14Å; T439-L443 VanDerWaalsContact O-CB 3.29Å; T439-L443 WeakPolarHBondContact O-CB 3.35Å; T439-L443 WeakPolarHBondContact O-CG 3.47Å; T439-L443 PolarHBondContact O-N 3.45Å; I440-L443 PolarHBondContact O-N 3.16Å; L443-G445 VanDerWaalsContact C-N 3.34Å; L443-I446 PolarHBondContact O-N 2.85Å; L443-G447 PolarHBondContact O-N 3.43Å
444	I	86.8	Confident	88.1	Confident	72 Å²	72	50.4 Å²	50.4	37%	0.369	28%	0.284	S	S	.	.	H	α-helix	trans	-61.7	-45.6	173.1	-68.2	165.5	0	0	0	110	Y383 I440 N441 S442 I446 G447 I448	Y383-I444 HydrophobicContact CE1-CB 4.19Å; Y383-I444 HydrophobicContact CE1-CD1 4.4Å; Y383-I444 HydrophobicContact CE1-CG2 4.24Å; I440-I444 HydrophobicContact CG2-CD1 3.93Å; I440-I444 VanDerWaalsContact O-CG1 3.29Å; I440-I444 WeakPolarHBondContact O-CG1 3.47Å; I440-I444 PolarHBondContact O-N 3.08Å; N441-I444 PolarHBondContact O-N 3.19Å; S442-I444 PolarHBondContact O-N 2.92Å; I444-I446 PolarHBondContact O-N 3.39Å; I444-G447 PolarHBondContact O-N 2.84Å; I444-I448 HydrophobicContact CG2-CD1 3.88Å; I444-I448 HydrophobicContact CG2-CG1 4.47Å; I444-I448 WeakPolarHBondContact O-CG1 3.44Å; I444-I448 PolarHBondContact O-N 3.33Å
445	G	85.8	Confident	88.3	Confident	3 Å²	3	52.4 Å²	52.4	3%	0.031	30%	0.296	C	S	.	.	H	α-helix	trans	-57.7	-47.1	176.1	0	0	0	0	0	112.7	N441 S442 L443 I448 A449	N441-G445 PolarHBondContact O-N 3.41Å; N441-G445 VanDerWaalsContact O-N 3.13Å; S442-G445 PolarHBondContact O-N 3.46Å; L443-G445 VanDerWaalsContact C-N 3.34Å; G445-I448 PolarHBondContact O-N 3.07Å; G445-A449 PolarHBondContact O-N 3.43Å
446	I	89.6	Confident	88.4	Confident	58 Å²	58	51.1 Å²	51.1	30%	0.297	29%	0.287	S	S	.	.	H	α-helix	trans	-62.3	-44.7	175.1	-67.1	170.5	0	0	0	110.9	F386 L435 S442 L443 I444 I448 A449 L450	F386-I446 HydrophobicContact CE1-CD1 4.38Å; F386-I446 HydrophobicContact CE1-CG1 3.77Å; F386-I446 HydrophobicContact CZ-CD1 3.93Å; F386-I446 HydrophobicContact CZ-CG1 3.83Å; L435-I446 HydrophobicContact CD2-CD1 3.72Å; S442-I446 WeakPolarHBondContact O-CG1 3.36Å; S442-I446 PolarHBondContact O-N 3.02Å; L443-I446 PolarHBondContact O-N 2.85Å; I444-I446 PolarHBondContact O-N 3.39Å; I446-I448 VanDerWaalsContact C-N 3.34Å; I446-I448 PolarHBondContact O-N 3.46Å; I446-A449 PolarHBondContact O-N 3.45Å; I446-L450 HydrophobicContact CG2-CD1 3.69Å; I446-L450 HydrophobicContact CG2-CG 4.07Å; I446-L450 WeakPolarHBondContact O-CB 3.32Å; I446-L450 WeakPolarHBondContact O-CG 3.46Å; I446-L450 PolarHBondContact O-N 2.8Å
447	G	91.3	Very high	88.4	Confident	40 Å²	40	49.7 Å²	49.7	41%	0.412	28%	0.284	S	S	.	.	H	α-helix	trans	-59.8	-43.4	179.7	0	0	0	0	0	112.4	L443 I444 L450 S451	L443-G447 PolarHBondContact O-N 3.43Å; I444-G447 PolarHBondContact O-N 2.84Å; G447-L450 PolarHBondContact O-N 2.88Å; G447-S451 WeakPolarHBondContact O-CB 3.48Å; G447-S451 PolarHBondContact O-N 2.94Å
448	I	89.1	Confident	88.5	Confident	41 Å²	41	51.8 Å²	51.8	21%	0.21	29%	0.291	C	S	.	.	H	α-helix	trans	-67	-42.2	175.7	-64.7	168.4	0	0	0	110.6	W120 L124 I125 I444 G445 I446 L450 S451	W120-I448 PolarHBondContact NE1-O 3.35Å; L124-I448 HydrophobicContact CB-CG2 3.91Å; L124-I448 HydrophobicContact CD1-CG2 3.88Å; I125-I448 HydrophobicContact CD1-CB 3.71Å; I125-I448 HydrophobicContact CD1-CD1 4.09Å; I125-I448 HydrophobicContact CD1-CG2 3.65Å; I125-I448 HydrophobicContact CG1-CB 4.26Å; I125-I448 HydrophobicContact CG1-CD1 4.2Å; I125-I448 HydrophobicContact CG1-CG2 3.71Å; I444-I448 HydrophobicContact CG2-CD1 3.88Å; I444-I448 HydrophobicContact CG2-CG1 4.47Å; I444-I448 WeakPolarHBondContact O-CG1 3.44Å; I444-I448 PolarHBondContact O-N 3.33Å; G445-I448 PolarHBondContact O-N 3.07Å; I446-I448 VanDerWaalsContact C-N 3.34Å; I446-I448 PolarHBondContact O-N 3.46Å; I448-L450 PolarHBondContact O-N 3.25Å; I448-S451 WeakPolarHBondContact O-CB 3.07Å; I448-S451 PolarHBondContact O-N 3.26Å; I448-S451 PolarHBondContact O-OG 3.32Å
449	A	89.8	Confident	88.3	Confident	16 Å²	16	51.9 Å²	51.9	13%	0.132	29%	0.294	C	S	.	.	H	α-helix	trans	-60.6	-45.3	175.2	0	0	0	0	0	111.7	I117 G445 I446 S451 G452	I117-A449 HydrophobicContact CG2-CB 4.43Å; G445-A449 PolarHBondContact O-N 3.43Å; I446-A449 PolarHBondContact O-N 3.45Å; A449-S451 VanDerWaalsContact C-N 3.31Å; A449-S451 PolarHBondContact O-N 2.78Å; A449-G452 PolarHBondContact O-N 3.09Å; A449-G452 VanDerWaalsContact O-N 3.13Å
450	L	92.5	Very high	88	Confident	105 Å²	105	50.4 Å²	50.4	55%	0.55	29%	0.286	S	S	.	.	H	α-helix	trans	-69.2	-25.5	177.9	-69.7	179.5	0	0	0	113.2	I446 G447 I448 G452 V453 P454	I446-L450 HydrophobicContact CG2-CD1 3.69Å; I446-L450 HydrophobicContact CG2-CG 4.07Å; I446-L450 WeakPolarHBondContact O-CB 3.32Å; I446-L450 WeakPolarHBondContact O-CG 3.46Å; I446-L450 PolarHBondContact O-N 2.8Å; G447-L450 PolarHBondContact O-N 2.88Å; I448-L450 PolarHBondContact O-N 3.25Å; L450-G452 PolarHBondContact O-N 3.49Å; L450-G452 VanDerWaalsContact O-N 3.14Å; L450-V453 HydrophobicContact CD2-CG2 4.28Å; L450-V453 VanDerWaalsContact O-CB 3.3Å; L450-V453 WeakPolarHBondContact O-CB 3.42Å; L450-V453 WeakPolarHBondContact O-CG2 3.28Å; L450-V453 PolarHBondContact O-N 3.15Å; L450-P454 WeakPolarHBondContact O-CD 3.37Å
451	S	94.1	Very high	87.7	Confident	47 Å²	47	52.2 Å²	52.2	33%	0.329	29%	0.286	S	S	.	.	H	α-helix	trans	-60.7	-20.9	171.6	79.3	0	0	0	0	112.6	W120 G447 I448 A449 V453 P454	W120-S451 PolarHBondContact NE1-OG 3.49Å; W120-S451 VanDerWaalsContact NE1-OG 3.11Å; G447-S451 WeakPolarHBondContact O-CB 3.48Å; G447-S451 PolarHBondContact O-N 2.94Å; I448-S451 WeakPolarHBondContact O-CB 3.07Å; I448-S451 PolarHBondContact O-N 3.26Å; I448-S451 PolarHBondContact O-OG 3.32Å; A449-S451 VanDerWaalsContact C-N 3.31Å; A449-S451 PolarHBondContact O-N 2.78Å; S451-V453 VanDerWaalsContact C-N 3.3Å; S451-V453 PolarHBondContact O-N 3.2Å; S451-P454 VanDerWaalsContact O-CD 3.27Å; S451-P454 WeakPolarHBondContact O-CD 3.48Å; S451-P454 VanDerWaalsContact O-CG 3.29Å; S451-P454 WeakPolarHBondContact O-CG 3.36Å
452	G	90.7	Very high	87.4	Confident	0 Å²	0	53.2 Å²	53.2	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-68.9	-25.1	172.2	0	0	0	0	0	113.5	F116 W120 A449 L450 V455 Y456	F116-G452 WeakPolarHBondContact CE1-O 3.07Å; W120-G452 VanDerWaalsContact CD1-CA 3.45Å; A449-G452 PolarHBondContact O-N 3.09Å; A449-G452 VanDerWaalsContact O-N 3.13Å; L450-G452 PolarHBondContact O-N 3.49Å; L450-G452 VanDerWaalsContact O-N 3.14Å; G452-V455 PolarHBondContact O-N 3.07Å; G452-Y456 WeakPolarHBondContact O-CB 3.12Å; G452-Y456 PolarHBondContact O-N 3.31Å
453	V	92.4	Very high	86.8	Confident	40 Å²	40	56.3 Å²	56.3	24%	0.242	31%	0.312	C	S	.	.	H	α-helix	trans	-59.6	-54.9	-178.4	-179.6	0	0	0	0	112.6	F113 I117 L450 S451 V455 Y456 F457	F113-V453 HydrophobicContact CE2-CG1 4.24Å; F113-V453 HydrophobicContact CE2-CG2 4.21Å; F113-V453 HydrophobicContact CZ-CG1 4.33Å; F113-V453 HydrophobicContact CZ-CG2 3.93Å; I117-V453 HydrophobicContact CD1-CG2 3.87Å; L450-V453 HydrophobicContact CD2-CG2 4.28Å; L450-V453 VanDerWaalsContact O-CB 3.3Å; L450-V453 WeakPolarHBondContact O-CB 3.42Å; L450-V453 WeakPolarHBondContact O-CG2 3.28Å; L450-V453 PolarHBondContact O-N 3.15Å; S451-V453 VanDerWaalsContact C-N 3.3Å; S451-V453 PolarHBondContact O-N 3.2Å; V453-V455 VanDerWaalsContact C-N 3.27Å; V453-V455 PolarHBondContact O-N 3.37Å; V453-Y456 PolarHBondContact O-N 2.82Å; V453-F457 HydrophobicContact CG1-CD2 3.97Å; V453-F457 HydrophobicContact CG1-CE2 3.8Å; V453-F457 VanDerWaalsContact O-CD2 3.26Å; V453-F457 WeakPolarHBondContact O-CD2 3.29Å; V453-F457 PolarHBondContact O-N 3.14Å
454	P	91.3	Very high	85.9	Confident	71 Å²	71	54.2 Å²	54.2	46%	0.461	31%	0.309	S	S	.	.	H	α-helix	trans	-61.9	-36.3	177.1	23.9	-34.3	0	0	0	112.1	L450 S451 F457 L458	L450-P454 WeakPolarHBondContact O-CD 3.37Å; S451-P454 VanDerWaalsContact O-CD 3.27Å; S451-P454 WeakPolarHBondContact O-CD 3.48Å; S451-P454 VanDerWaalsContact O-CG 3.29Å; S451-P454 WeakPolarHBondContact O-CG 3.36Å; P454-F457 PolarHBondContact O-N 2.9Å; P454-L458 WeakPolarHBondContact O-CB 3.49Å; P454-L458 VanDerWaalsContact O-CG 3.26Å; P454-L458 WeakPolarHBondContact O-CG 3.29Å; P454-L458 PolarHBondContact O-N 2.92Å
455	V	89.4	Confident	85	Confident	42 Å²	42	56 Å²	56	26%	0.255	32%	0.324	S	S	.	.	H	α-helix	trans	-65.3	-42	178.1	-178.6	0	0	0	0	111.1	F116 W120 G452 V453 F457 L458 C459	F116-V455 HydrophobicContact CZ-CB 4.18Å; F116-V455 HydrophobicContact CZ-CG1 3.85Å; W120-V455 HydrophobicContact CH2-CB 4.42Å; W120-V455 HydrophobicContact CH2-CG1 4.09Å; W120-V455 HydrophobicContact CH2-CG2 4Å; W120-V455 HydrophobicContact CZ2-CG2 4.02Å; W120-V455 HydrophobicContact CZ3-CG1 3.98Å; G452-V455 PolarHBondContact O-N 3.07Å; V453-V455 VanDerWaalsContact C-N 3.27Å; V453-V455 PolarHBondContact O-N 3.37Å; V455-F457 PolarHBondContact O-N 2.99Å; V455-L458 PolarHBondContact O-N 3.03Å; V455-C459 HydrophobicContact CG1-CB 4.44Å; V455-C459 VanDerWaalsContact O-CB 3.23Å; V455-C459 WeakPolarHBondContact O-CB 3.38Å; V455-C459 PolarHBondContact O-N 2.76Å
456	Y	88.5	Confident	84.5	Confident	31 Å²	31	63.7 Å²	63.7	12%	0.122	36%	0.356	C	S	.	.	I	π-helix	trans	-59.9	-47.5	176.6	179.3	-98.4	0	0	0	111.7	F113 F116 G452 V453 L458 C460 Y461	F113-Y456 HydrophobicContact CB-CE1 3.99Å; F113-Y456 AromaticContact CD2-CD1 3.49Å; F113-Y456 HydrophobicContact CD2-CD1 3.49Å; F113-Y456 VanDerWaalsContact CD2-CD1 3.49Å; F113-Y456 AromaticContact CD2-CE1 3.71Å; F113-Y456 HydrophobicContact CD2-CE1 3.71Å; F113-Y456 AromaticContact CD2-CG 3.9Å; F113-Y456 HydrophobicContact CD2-CG 3.9Å; F113-Y456 HydrophobicContact CE2-CD1 4.16Å; F113-Y456 HydrophobicContact CE2-CG 4.48Å; F113-Y456 HydrophobicContact CG-CE1 4.33Å; F113-Y456 PolarHBondContact N-OH 3.17Å; F116-Y456 HydrophobicContact CB-CD2 3.43Å; F116-Y456 VanDerWaalsContact CB-CD2 3.43Å; F116-Y456 HydrophobicContact CB-CE2 3.8Å; F116-Y456 HydrophobicContact CB-CG 4.45Å; F116-Y456 AromaticContact CD1-CD2 3.81Å; F116-Y456 HydrophobicContact CD1-CD2 3.81Å; F116-Y456 HydrophobicContact CD1-CG 4.16Å; F116-Y456 AromaticContact CD2-CD2 3.95Å; F116-Y456 HydrophobicContact CD2-CD2 3.95Å; F116-Y456 AromaticContact CG-CD2 3.44Å; F116-Y456 HydrophobicContact CG-CD2 3.44Å; F116-Y456 VanDerWaalsContact CG-CD2 3.44Å; F116-Y456 HydrophobicContact CG-CE2 4.28Å; F116-Y456 HydrophobicContact CG-CG 4.25Å; G452-Y456 WeakPolarHBondContact O-CB 3.12Å; G452-Y456 PolarHBondContact O-N 3.31Å; V453-Y456 PolarHBondContact O-N 2.82Å; Y456-L458 VanDerWaalsContact C-N 3.34Å; Y456-L458 PolarHBondContact O-N 3.33Å; Y456-C460 HydrophobicContact CD2-CB 3.59Å; Y456-C460 HydrophobicContact CE2-CB 3.73Å; Y456-C460 HydrophobicContact CG-CB 4.26Å; Y456-C460 WeakPolarHBondContact O-CA 3.3Å; Y456-C460 WeakPolarHBondContact O-CB 3.44Å; Y456-C460 PolarHBondContact O-N 3.06Å; Y456-Y461 PolarHBondContact O-N 3.2Å
457	F	87.3	Confident	84.1	Confident	97 Å²	97	63.8 Å²	63.8	43%	0.425	35%	0.353	S	S	.	.	I	π-helix	trans	-66.8	-36.8	-179.5	-76.1	-68.8	0	0	0	112.3	F113 V453 P454 V455 Y461 T462	F113-F457 HydrophobicContact CE2-CE2 4.31Å; V453-F457 HydrophobicContact CG1-CD2 3.97Å; V453-F457 HydrophobicContact CG1-CE2 3.8Å; V453-F457 VanDerWaalsContact O-CD2 3.26Å; V453-F457 WeakPolarHBondContact O-CD2 3.29Å; V453-F457 PolarHBondContact O-N 3.14Å; P454-F457 PolarHBondContact O-N 2.9Å; V455-F457 PolarHBondContact O-N 2.99Å; F457-Y461 AromaticContact CD1-CD1 3.94Å; F457-Y461 HydrophobicContact CD1-CD1 3.94Å; F457-Y461 AromaticContact CD1-CG 4Å; F457-Y461 HydrophobicContact CD1-CG 4Å; F457-Y461 HydrophobicContact CE1-CD1 4.42Å; F457-Y461 HydrophobicContact CE1-CG 4.37Å; F457-T462 WeakPolarHBondContact O-CB 3.22Å; F457-T462 VanDerWaalsContact O-CG2 3.31Å; F457-T462 WeakPolarHBondContact O-CG2 3.38Å; F457-T462 PolarHBondContact O-N 2.8Å; F457-T462 PolarHBondContact O-OG1 3.01Å
458	L	84.1	Confident	83.7	Confident	87 Å²	87	64.5 Å²	64.5	46%	0.455	35%	0.35	S	S	.	.	I	π-helix	trans	-79.2	-31.5	-179.8	-71.9	171.1	0	0	0	114.6	P454 V455 Y456 T462	P454-L458 WeakPolarHBondContact O-CB 3.49Å; P454-L458 VanDerWaalsContact O-CG 3.26Å; P454-L458 WeakPolarHBondContact O-CG 3.29Å; P454-L458 PolarHBondContact O-N 2.92Å; V455-L458 PolarHBondContact O-N 3.03Å; Y456-L458 VanDerWaalsContact C-N 3.34Å; Y456-L458 PolarHBondContact O-N 3.33Å; L458-T462 VanDerWaalsContact C-OG1 3.22Å; L458-T462 PolarHBondContact O-OG1 3.42Å
459	C	80.6	Confident	83.4	Confident	33 Å²	33	69 Å²	69	22%	0.223	37%	0.374	C	S	.	.	I	π-helix	trans	-110.2	-34.7	-172.6	-65.9	0	0	0	0	113.2	V455 R467	V455-C459 HydrophobicContact CG1-CB 4.44Å; V455-C459 VanDerWaalsContact O-CB 3.23Å; V455-C459 WeakPolarHBondContact O-CB 3.38Å; V455-C459 PolarHBondContact O-N 2.76Å; C459-R467 PolarHBondContact O-NE 3.08Å; C459-R467 PolarHBondContact O-NH2 3.33Å
460	C	79.9	Confident	83.2	Confident	31 Å²	31	77.4 Å²	77.4	21%	0.209	40%	0.402	C	S	.	.	I	π-helix	trans	-104.3	-51.2	-173.5	-57.7	0	0	0	0	112.1	H342 Y456	H342-C460 PolarHBondContact O-SG 3.29Å; Y456-C460 HydrophobicContact CD2-CB 3.59Å; Y456-C460 HydrophobicContact CE2-CB 3.73Å; Y456-C460 HydrophobicContact CG-CB 4.26Å; Y456-C460 WeakPolarHBondContact O-CA 3.3Å; Y456-C460 WeakPolarHBondContact O-CB 3.44Å; Y456-C460 PolarHBondContact O-N 3.06Å
461	Y	82	Confident	82.8	Confident	161 Å²	161	73.8 Å²	73.8	63%	0.631	38%	0.384	S	S	*	.	I	π-helix	trans	-73.2	-38.8	-175.7	-175	-101.8	0	0	0	113	Y456 F457 P463	Y456-Y461 PolarHBondContact O-N 3.2Å; F457-Y461 AromaticContact CD1-CD1 3.94Å; F457-Y461 HydrophobicContact CD1-CD1 3.94Å; F457-Y461 AromaticContact CD1-CG 4Å; F457-Y461 HydrophobicContact CD1-CG 4Å; F457-Y461 HydrophobicContact CE1-CD1 4.42Å; F457-Y461 HydrophobicContact CE1-CG 4.37Å; Y461-P463 WeakPolarHBondContact O-CD 3.28Å
462	T	77.3	Confident	82.2	Confident	39 Å²	39	75.5 Å²	75.5	24%	0.239	38%	0.383	C	S	.	.	S	Bend	trans	-76.2	124.2	178.7	40.1	0	0	0	0	110.4	F457 L458 A464 R467	F457-T462 WeakPolarHBondContact O-CB 3.22Å; F457-T462 VanDerWaalsContact O-CG2 3.31Å; F457-T462 WeakPolarHBondContact O-CG2 3.38Å; F457-T462 PolarHBondContact O-N 2.8Å; F457-T462 PolarHBondContact O-OG1 3.01Å; L458-T462 VanDerWaalsContact C-OG1 3.22Å; L458-T462 PolarHBondContact O-OG1 3.42Å; T462-A464 PolarHBondContact O-N 2.98Å; T462-R467 PolarHBondContact O-NE 2.85Å
463	P	73.1	Confident	81.9	Confident	69 Å²	69	78.3 Å²	78.3	45%	0.448	40%	0.402	S	S	.	.			trans	-52.4	142.7	176.5	-25.9	33	0	0	0	110.3	Y461 T465 K466 R467	Y461-P463 WeakPolarHBondContact O-CD 3.28Å; P463-T465 PolarHBondContact O-N 3.44Å; P463-K466 HydrophobicContact CG-CD 4.44Å; P463-K466 PolarHBondContact O-N 3.01Å; P463-R467 PolarHBondContact O-N 3.46Å
464	A	69	Low	81.6	Confident	55 Å²	55	82.2 Å²	82.2	46%	0.455	42%	0.416	S	S	.	.	T	Hydrogen-bonded Turn	trans	-51.1	-29	179.3	0	0	0	0	0	112.3	T462 R472	T462-A464 PolarHBondContact O-N 2.98Å; A464-R472 VanDerWaalsContact O-CD 3.28Å; A464-R472 WeakPolarHBondContact O-CD 3.46Å; A464-R472 PolarHBondContact O-NE 3.43Å; A464-R472 PolarHBondContact O-NH1 3.04Å; A464-R472 VanDerWaalsContact O-NH1 3.16Å; A464-R472 PolarHBondContact O-NH2 2.9Å
465	T	67.4	Low	81.3	Confident	109 Å²	109	80.9 Å²	80.9	67%	0.669	41%	0.405	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.4	-10.6	177.1	55.1	0	0	0	0	116.1	P463 R472	P463-T465 PolarHBondContact O-N 3.44Å; T465-R472 VanDerWaalsContact C-CZ 3.48Å; T465-R472 PolarHBondContact O-NH2 3.46Å
466	K	75.9	Confident	81.1	Confident	165 Å²	165	81.5 Å²	81.5	72%	0.717	41%	0.414	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.4	-6.2	175.3	-66.6	-173.7	179.7	179.7	0	114	P463	P463-K466 HydrophobicContact CG-CD 4.44Å; P463-K466 PolarHBondContact O-N 3.01Å
467	R	80.9	Confident	81.1	Confident	60 Å²	60	87.3 Å²	87.3	23%	0.226	44%	0.44	C	S	.	.	S	Bend	trans	-62.6	146.8	176.6	-62.6	-178.9	-165.1	160.2	5.5	111.5	C459 T462 P463 R472	C459-R467 PolarHBondContact O-NE 3.08Å; C459-R467 PolarHBondContact O-NH2 3.33Å; T462-R467 PolarHBondContact O-NE 2.85Å; P463-R467 PolarHBondContact O-N 3.46Å; R467-R472 HydrophobicContact CB-CG 3.91Å; R467-R472 VanDerWaalsContact O-CZ 3.28Å; R467-R472 PolarHBondContact O-NE 2.82Å; R467-R472 PolarHBondContact O-NH2 3.43Å
468	P	83.2	Confident	81.1	Confident	55 Å²	55	84.1 Å²	84.1	36%	0.357	43%	0.43	S	S	.	.			trans	-53.1	139.7	175.3	-25.9	34.6	0	0	0	112.5	W470 L471 R472	P468-W470 VanDerWaalsContact C-N 3.28Å; P468-W470 PolarHBondContact O-N 3.15Å; P468-L471 HydrophobicContact CB-CB 4.32Å; P468-L471 PolarHBondContact O-N 3.38Å; P468-L471 VanDerWaalsContact O-N 3.11Å; P468-R472 PolarHBondContact O-N 3.4Å; P468-R472 VanDerWaalsContact O-N 3.13Å
469	L	81.9	Confident	81.1	Confident	135 Å²	135	80.4 Å²	80.4	71%	0.707	41%	0.412	S	S	*	.	H	α-helix	trans	-58.8	-37.5	-176.5	-74.5	168.7	0	0	0	113	R472 S473	L469-R472 PolarHBondContact O-N 2.88Å; L469-S473 WeakPolarHBondContact O-CB 3.4Å; L469-S473 PolarHBondContact O-N 3.2Å; L469-S473 PolarHBondContact O-OG 3.37Å
470	W	86	Confident	81.5	Confident	193 Å²	193	83 Å²	83	73%	0.731	42%	0.423	S	S	*	.	H	α-helix	trans	-62.5	-42.7	177.2	83.5	-68.8	0	0	0	111.6	P468 S473 F474	P468-W470 VanDerWaalsContact C-N 3.28Å; P468-W470 PolarHBondContact O-N 3.15Å; W470-S473 PolarHBondContact O-N 3.1Å; W470-F474 VanDerWaalsContact O-CB 3.29Å; W470-F474 WeakPolarHBondContact O-CB 3.45Å; W470-F474 PolarHBondContact O-N 2.96Å
471	L	83.5	Confident	82	Confident	29 Å²	29	86.7 Å²	86.7	15%	0.152	44%	0.44	C	S	.	.	H	α-helix	trans	-67.2	-43	-179.6	-178.3	62.3	0	0	0	111.2	P468 F474 I475	P468-L471 HydrophobicContact CB-CB 4.32Å; P468-L471 PolarHBondContact O-N 3.38Å; P468-L471 VanDerWaalsContact O-N 3.11Å; L471-F474 PolarHBondContact O-N 3.31Å; L471-I475 HydrophobicContact CD1-CD1 4.04Å; L471-I475 HydrophobicContact CD1-CG1 4.32Å; L471-I475 HydrophobicContact CG-CD1 3.95Å; L471-I475 VanDerWaalsContact O-CG1 3.3Å; L471-I475 WeakPolarHBondContact O-CG1 3.25Å; L471-I475 PolarHBondContact O-N 2.88Å
472	R	81.4	Confident	82.3	Confident	84 Å²	84	81 Å²	81	32%	0.317	42%	0.42	S	S	.	.	H	α-helix	trans	-62.9	-45	174.2	-66	-170.1	-139.1	-179.5	0.5	112.1	A464 T465 R467 P468 L469 F474 I475 A476	A464-R472 VanDerWaalsContact O-CD 3.28Å; A464-R472 WeakPolarHBondContact O-CD 3.46Å; A464-R472 PolarHBondContact O-NE 3.43Å; A464-R472 PolarHBondContact O-NH1 3.04Å; A464-R472 VanDerWaalsContact O-NH1 3.16Å; A464-R472 PolarHBondContact O-NH2 2.9Å; T465-R472 VanDerWaalsContact C-CZ 3.48Å; T465-R472 PolarHBondContact O-NH2 3.46Å; R467-R472 HydrophobicContact CB-CG 3.91Å; R467-R472 VanDerWaalsContact O-CZ 3.28Å; R467-R472 PolarHBondContact O-NE 2.82Å; R467-R472 PolarHBondContact O-NH2 3.43Å; P468-R472 PolarHBondContact O-N 3.4Å; P468-R472 VanDerWaalsContact O-N 3.13Å; L469-R472 PolarHBondContact O-N 2.88Å; R472-F474 VanDerWaalsContact C-N 3.27Å; R472-F474 PolarHBondContact O-N 3.11Å; R472-I475 PolarHBondContact O-N 2.7Å; R472-A476 VanDerWaalsContact O-CB 3.26Å; R472-A476 WeakPolarHBondContact O-CB 3.18Å; R472-A476 PolarHBondContact O-N 2.83Å
473	S	84.4	Confident	82.8	Confident	58 Å²	58	83.1 Å²	83.1	41%	0.406	43%	0.427	S	S	.	.	H	α-helix	trans	-62.4	-38.9	178.4	-59.9	0	0	0	0	111.1	L469 W470 K477	L469-S473 WeakPolarHBondContact O-CB 3.4Å; L469-S473 PolarHBondContact O-N 3.2Å; L469-S473 PolarHBondContact O-OG 3.37Å; W470-S473 PolarHBondContact O-N 3.1Å; S473-K477 VanDerWaalsContact O-CB 3.26Å; S473-K477 WeakPolarHBondContact O-CB 3.41Å; S473-K477 WeakPolarHBondContact O-CG 3.36Å; S473-K477 PolarHBondContact O-N 3.2Å
474	F	86.8	Confident	83.5	Confident	123 Å²	123	87.5 Å²	87.5	54%	0.539	44%	0.439	S	S	.	.	H	α-helix	trans	-65.1	-53.5	175.8	-180	-99.7	0	0	0	111.5	W470 L471 R472 A476 K477 C478	W470-F474 VanDerWaalsContact O-CB 3.29Å; W470-F474 WeakPolarHBondContact O-CB 3.45Å; W470-F474 PolarHBondContact O-N 2.96Å; L471-F474 PolarHBondContact O-N 3.31Å; R472-F474 VanDerWaalsContact C-N 3.27Å; R472-F474 PolarHBondContact O-N 3.11Å; F474-A476 VanDerWaalsContact C-N 3.3Å; F474-A476 PolarHBondContact O-N 2.84Å; F474-K477 PolarHBondContact O-N 2.77Å; F474-C478 VanDerWaalsContact CZ-SG 3.5Å; F474-C478 WeakPolarHBondContact O-CB 3.17Å; F474-C478 PolarHBondContact O-N 3.01Å; F474-C478 PolarHBondContact O-SG 3.35Å; F474-C478 VanDerWaalsContact O-SG 3.4Å
475	I	84.6	Confident	84.6	Confident	43 Å²	43	90.2 Å²	90.2	22%	0.221	45%	0.45	C	S	.	.	H	α-helix	trans	-58	-43.4	178.8	-67.5	168.1	0	0	0	110.8	F346 L471 R472 G479	F346-I475 HydrophobicContact CE1-CG2 4.33Å; L471-I475 HydrophobicContact CD1-CD1 4.04Å; L471-I475 HydrophobicContact CD1-CG1 4.32Å; L471-I475 HydrophobicContact CG-CD1 3.95Å; L471-I475 VanDerWaalsContact O-CG1 3.3Å; L471-I475 WeakPolarHBondContact O-CG1 3.25Å; L471-I475 PolarHBondContact O-N 2.88Å; R472-I475 PolarHBondContact O-N 2.7Å; I475-G479 PolarHBondContact O-N 2.72Å
476	A	84.6	Confident	85.5	Confident	54 Å²	54	85.8 Å²	85.8	45%	0.446	42%	0.423	S	S	.	.	H	α-helix	trans	-65.9	-44.9	178.1	0	0	0	0	0	112.3	R472 F474 G479 I480	R472-A476 VanDerWaalsContact O-CB 3.26Å; R472-A476 WeakPolarHBondContact O-CB 3.18Å; R472-A476 PolarHBondContact O-N 2.83Å; F474-A476 VanDerWaalsContact C-N 3.3Å; F474-A476 PolarHBondContact O-N 2.84Å; A476-G479 PolarHBondContact O-N 2.97Å; A476-I480 VanDerWaalsContact O-CG1 3.29Å; A476-I480 WeakPolarHBondContact O-CG1 3.37Å; A476-I480 PolarHBondContact O-N 2.87Å
477	K	88.9	Confident	86.2	Confident	154 Å²	154	84.1 Å²	84.1	67%	0.67	41%	0.413	S	S	*	.	H	α-helix	trans	-63.7	-44.6	176.9	-76.4	175.2	-177.8	-176.2	0	111.7	S473 F474 I480 L481	S473-K477 VanDerWaalsContact O-CB 3.26Å; S473-K477 WeakPolarHBondContact O-CB 3.41Å; S473-K477 WeakPolarHBondContact O-CG 3.36Å; S473-K477 PolarHBondContact O-N 3.2Å; F474-K477 PolarHBondContact O-N 2.77Å; K477-I480 PolarHBondContact O-N 2.7Å; K477-L481 VanDerWaalsContact O-CB 3.29Å; K477-L481 WeakPolarHBondContact O-CB 3.33Å; K477-L481 PolarHBondContact O-N 3.01Å
478	C	86.6	Confident	86.4	Confident	30 Å²	30	81.3 Å²	81.3	20%	0.203	40%	0.403	C	S	.	.	H	α-helix	trans	-61.9	-44.9	174.7	-74	0	0	0	0	111.1	F474 L481 I482	F474-C478 VanDerWaalsContact CZ-SG 3.5Å; F474-C478 WeakPolarHBondContact O-CB 3.17Å; F474-C478 PolarHBondContact O-N 3.01Å; F474-C478 PolarHBondContact O-SG 3.35Å; F474-C478 VanDerWaalsContact O-SG 3.4Å; C478-L481 PolarHBondContact O-N 3.08Å; C478-I482 WeakPolarHBondContact O-CB 3.29Å; C478-I482 VanDerWaalsContact O-CG1 3.24Å; C478-I482 WeakPolarHBondContact O-CG1 3.3Å; C478-I482 PolarHBondContact O-N 2.97Å
479	G	85.5	Confident	86.5	Confident	9 Å²	9	81.7 Å²	81.7	9%	0.093	40%	0.404	C	S	.	.	H	α-helix	trans	-57.4	-51	176.2	0	0	0	0	0	112.1	I475 A476 L481 I482 Q483	I475-G479 PolarHBondContact O-N 2.72Å; A476-G479 PolarHBondContact O-N 2.97Å; G479-L481 PolarHBondContact O-N 3.1Å; G479-I482 PolarHBondContact O-N 2.94Å; G479-Q483 VanDerWaalsContact O-CB 3.25Å; G479-Q483 WeakPolarHBondContact O-CB 3.45Å; G479-Q483 PolarHBondContact O-N 3.41Å
480	I	87.4	Confident	86.4	Confident	87 Å²	87	78.7 Å²	78.7	45%	0.446	39%	0.388	S	S	.	.	H	α-helix	trans	-63.2	-40.8	177.8	-66.5	165.2	0	0	0	111.5	A476 K477 Q483 K484	A476-I480 VanDerWaalsContact O-CG1 3.29Å; A476-I480 WeakPolarHBondContact O-CG1 3.37Å; A476-I480 PolarHBondContact O-N 2.87Å; K477-I480 PolarHBondContact O-N 2.7Å; I480-Q483 PolarHBondContact O-N 3.34Å; I480-K484 HydrophobicContact CG2-CD 4.08Å; I480-K484 HydrophobicContact CG2-CG 4.48Å; I480-K484 WeakPolarHBondContact O-CB 3.44Å; I480-K484 VanDerWaalsContact O-CG 3.32Å; I480-K484 WeakPolarHBondContact O-CG 3.45Å; I480-K484 PolarHBondContact O-N 3.43Å
481	L	90.8	Very high	85.6	Confident	109 Å²	109	71.7 Å²	71.7	57%	0.571	37%	0.367	S	S	*	.	H	α-helix	trans	-62	-49.9	177.4	178.7	66	0	0	0	110.7	K477 C478 G479 Q483 K484 V485	K477-L481 VanDerWaalsContact O-CB 3.29Å; K477-L481 WeakPolarHBondContact O-CB 3.33Å; K477-L481 PolarHBondContact O-N 3.01Å; C478-L481 PolarHBondContact O-N 3.08Å; G479-L481 PolarHBondContact O-N 3.1Å; L481-Q483 VanDerWaalsContact C-N 3.32Å; L481-Q483 PolarHBondContact O-N 3.3Å; L481-K484 PolarHBondContact O-N 3.18Å; L481-V485 HydrophobicContact CD1-CG2 3.87Å; L481-V485 HydrophobicContact CG-CG2 4.26Å; L481-V485 WeakPolarHBondContact O-CB 3.49Å; L481-V485 VanDerWaalsContact O-CG2 3.24Å; L481-V485 WeakPolarHBondContact O-CG2 3.34Å; L481-V485 PolarHBondContact O-N 2.84Å
482	I	88.2	Confident	84.3	Confident	41 Å²	41	79.5 Å²	79.5	21%	0.21	40%	0.403	C	S	.	.	H	α-helix	trans	-61.4	-43.7	178.1	-69.8	167.9	0	0	0	110	F346 P359 C478 G479 K484 V485 C486	F346-I482 HydrophobicContact CB-CD1 4.21Å; F346-I482 HydrophobicContact CB-CG2 4.49Å; F346-I482 HydrophobicContact CD2-CD1 3.36Å; F346-I482 HydrophobicContact CE2-CD1 3.81Å; F346-I482 HydrophobicContact CG-CD1 3.84Å; P359-I482 HydrophobicContact CB-CG2 3.81Å; P359-I482 HydrophobicContact CG-CG2 3.51Å; C478-I482 WeakPolarHBondContact O-CB 3.29Å; C478-I482 VanDerWaalsContact O-CG1 3.24Å; C478-I482 WeakPolarHBondContact O-CG1 3.3Å; C478-I482 PolarHBondContact O-N 2.97Å; G479-I482 PolarHBondContact O-N 2.94Å; I482-K484 VanDerWaalsContact C-N 3.32Å; I482-K484 PolarHBondContact O-N 3.29Å; I482-V485 PolarHBondContact O-N 3.13Å; I482-C486 WeakPolarHBondContact O-CA 3.39Å; I482-C486 WeakPolarHBondContact O-CB 3.42Å; I482-C486 PolarHBondContact O-N 3Å
483	Q	87.9	Confident	82.8	Confident	84 Å²	84	80.6 Å²	80.6	39%	0.393	41%	0.413	S	S	.	.	H	α-helix	trans	-57.3	-44.5	177.2	-157.1	-175.1	-7.9	0	0	111.9	M349 G479 I480 L481 Y487 S488	M349-Q483 HydrophobicContact CE-CB 4.41Å; M349-Q483 HydrophobicContact CE-CG 4.43Å; M349-Q483 HydrophobicContact SD-CB 4.21Å; M349-Q483 HydrophobicContact SD-CG 4.25Å; G479-Q483 VanDerWaalsContact O-CB 3.25Å; G479-Q483 WeakPolarHBondContact O-CB 3.45Å; G479-Q483 PolarHBondContact O-N 3.41Å; I480-Q483 PolarHBondContact O-N 3.34Å; L481-Q483 VanDerWaalsContact C-N 3.32Å; L481-Q483 PolarHBondContact O-N 3.3Å; Q483-Y487 VanDerWaalsContact O-CA 3.25Å; Q483-Y487 WeakPolarHBondContact O-CA 3.18Å; Q483-Y487 PolarHBondContact O-N 2.88Å; Q483-S488 WeakPolarHBondContact CG-O 3.11Å; Q483-S488 PolarHBondContact O-N 3.15Å
484	K	89.1	Confident	80.7	Confident	161 Å²	161	83.2 Å²	83.2	70%	0.7	42%	0.422	S	S	*	.	H	α-helix	trans	-72.1	-44.2	178.7	-73	178.3	179.4	-175.8	0	112.8	I480 L481 I482	I480-K484 HydrophobicContact CG2-CD 4.08Å; I480-K484 HydrophobicContact CG2-CG 4.48Å; I480-K484 WeakPolarHBondContact O-CB 3.44Å; I480-K484 VanDerWaalsContact O-CG 3.32Å; I480-K484 WeakPolarHBondContact O-CG 3.45Å; I480-K484 PolarHBondContact O-N 3.43Å; L481-K484 PolarHBondContact O-N 3.18Å; I482-K484 VanDerWaalsContact C-N 3.32Å; I482-K484 PolarHBondContact O-N 3.29Å
485	V	90.8	Very high	78.1	Confident	111 Å²	111	84.4 Å²	84.4	67%	0.673	43%	0.434	S	S	*	.	H	α-helix	trans	-72.2	-43.2	-176.6	171.3	0	0	0	0	111.2	L481 I482	L481-V485 HydrophobicContact CD1-CG2 3.87Å; L481-V485 HydrophobicContact CG-CG2 4.26Å; L481-V485 WeakPolarHBondContact O-CB 3.49Å; L481-V485 VanDerWaalsContact O-CG2 3.24Å; L481-V485 WeakPolarHBondContact O-CG2 3.34Å; L481-V485 PolarHBondContact O-N 2.84Å; I482-V485 PolarHBondContact O-N 3.13Å
486	C	87.5	Confident	75.6	Confident	16 Å²	16	91.4 Å²	91.4	11%	0.108	46%	0.463	C	S	.	.	H	α-helix	trans	-91	-3.6	-177.3	-59.3	0	0	0	0	113.2	H351 I358 P359 I482 S488	H351-C486 PolarHBondContact CD2-O 3.47Å; I358-C486 HydrophobicContact CB-CB 4.46Å; I358-C486 HydrophobicContact CG2-CB 4.19Å; P359-C486 HydrophobicContact CG-CB 4.28Å; I482-C486 WeakPolarHBondContact O-CA 3.39Å; I482-C486 WeakPolarHBondContact O-CB 3.42Å; I482-C486 PolarHBondContact O-N 3Å; C486-S488 PolarHBondContact O-N 2.91Å
487	Y	89.3	Confident	72.9	Confident	130 Å²	130	93.5 Å²	93.5	51%	0.51	47%	0.474	S	S	.	.	T	Hydrogen-bonded Turn	trans	45.6	50.1	-175.5	-162.3	-110.1	0	0	0	112.2	V352 H353 Q483	V352-Y487 HydrophobicContact CB-CD1 4.02Å; V352-Y487 HydrophobicContact CB-CE1 3.76Å; V352-Y487 HydrophobicContact CG1-CE1 4.26Å; V352-Y487 HydrophobicContact CG2-CD1 4.11Å; V352-Y487 HydrophobicContact CG2-CE1 3.98Å; V352-Y487 PolarHBondContact N-O 3.11Å; H353-Y487 AromaticContact CD2-CE1 3.69Å; H353-Y487 AromaticContact NE2-CE1 3.59Å; Q483-Y487 VanDerWaalsContact O-CA 3.25Å; Q483-Y487 WeakPolarHBondContact O-CA 3.18Å; Q483-Y487 PolarHBondContact O-N 2.88Å
488	S	86.3	Confident	70.1	Confident	1 Å²	1	99 Å²	99	1%	0.007	50%	0.503	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-118.5	151.6	-171.7	57.8	0	0	0	0	111.2	I350 Q483 C486	I350-S488 CarbonylContact O-C 3.4Å; I350-S488 VanDerWaalsContact O-CA 3.22Å; I350-S488 WeakPolarHBondContact O-CA 3.42Å; I350-S488 WeakPolarHBondContact O-CB 3.39Å; Q483-S488 WeakPolarHBondContact CG-O 3.11Å; Q483-S488 PolarHBondContact O-N 3.15Å; C486-S488 PolarHBondContact O-N 2.91Å
489	V	84.6	Confident	69.3	Low	64 Å²	64	102.5 Å²	102.5	39%	0.388	52%	0.518	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-130.1	154	-179.2	-68.4	0	0	0	0	109.9	M349 I350 V352	M349-V489 CarbonylContact C-O 3.51Å; M349-V489 VanDerWaalsContact CA-O 3.31Å; M349-V489 WeakPolarHBondContact CA-O 3.36Å; I350-V489 PolarHBondContact N-O 2.9Å; I350-V489 PolarHBondContact O-N 3.28Å; V352-V489 HydrophobicContact CG2-CG1 3.81Å; V352-V489 HydrophobicContact CG2-CG2 4.01Å
490	L	79.9	Confident	68.4	Low	71 Å²	71	107.4 Å²	107.4	37%	0.372	54%	0.54	S	S	.	.	P	Polyproline II helix	trans	-65.7	141.2	168.1	-106.9	94	0	0	0	109.2	D345 M349	D345-L490 HydrophobicContact CB-CD1 3.86Å; D345-L490 HydrophobicContact CB-CD2 4.13Å; D345-L490 HydrophobicContact CB-CG 4.45Å; M349-L490 HydrophobicContact CE-CD1 3.72Å; M349-L490 HydrophobicContact CG-CD1 3.88Å
491	T	68.6	Low	67.4	Low	46 Å²	46	108.5 Å²	108.5	28%	0.282	55%	0.545	S	S	.	.	P	Polyproline II helix	trans	-68.4	140.4	163.1	45.1	0	0	0	0	109.2	F335 I350 M493	F335-T491 HydrophobicContact CE2-CG2 4.13Å; F335-T491 HydrophobicContact CZ-CG2 4.2Å; I350-T491 HydrophobicContact CB-CG2 4.45Å; I350-T491 HydrophobicContact CD1-CG2 3.3Å; I350-T491 HydrophobicContact CG1-CG2 3.85Å; T491-M493 PolarHBondContact O-N 3.38Å; T491-M493 VanDerWaalsContact O-N 3.07Å
492	E	57.5	Low	66	Low	193 Å²	193	108.5 Å²	108.5	90%	0.902	54%	0.544	S	S	*	.	P	Polyproline II helix	trans	-50.7	119.3	166.3	-72.9	176.3	170.4	0	0	107.8
493	M	50.3	Low	64.6	Low	108 Å²	108	112.7 Å²	112.7	53%	0.532	56%	0.564	S	S	.	*	P	Polyproline II helix	trans	-69.9	133.3	173.9	-70	-173	56.9	0	0	106.6	T491 D495	T491-M493 PolarHBondContact O-N 3.38Å; T491-M493 VanDerWaalsContact O-N 3.07Å; M493-D495 PolarHBondContact O-N 3.41Å
494	D	38.8	Very low	63	Low	113 Å²	113	114.6 Å²	114.6	60%	0.604	58%	0.576	S	S	*	*			trans	-51.8	107.2	165.2	-65.8	-41.5	0	0	0	106.8	R339 K496	R339-D494 IonicContact CZ-OD2 3.34Å; R339-D494 IonicContact NH2-OD2 3.59Å; R339-D494 PolarHBondContact NH2-OD2 2.83Å; D494-K496 PolarHBondContact O-N 3.39Å
495	D	32	Very low	61.2	Low	148 Å²	148	111.3 Å²	111.3	79%	0.791	57%	0.567	S	S	*	*			trans	-59.5	104.3	175.2	-95.7	-28.6	0	0	0	106.3	M493 S497	M493-D495 PolarHBondContact O-N 3.41Å; D495-S497 PolarHBondContact O-N 3.47Å
496	K	32.5	Very low	58.9	Low	189 Å²	189	111.3 Å²	111.3	82%	0.822	56%	0.559	S	S	*	*			trans	-73.4	70.8	165.5	-76.6	-177.2	180	169.7	0	107.4	D494	D494-K496 PolarHBondContact O-N 3.39Å
497	S	28.7	Very low	56.5	Low	98 Å²	98	119.3 Å²	119.3	69%	0.685	60%	0.596	S	S	*	*			trans	-104.7	77.9	160.7	58.9	0	0	0	0	108.4	D495	D495-S497 PolarHBondContact O-N 3.47Å
498	E	29.8	Very low	53.5	Low	270 Å²	270	118.3 Å²	118.3	100%	1.262	60%	0.604	S	S	*	*			trans	-134.2	0	152.7	-78.5	-166.7	158.4	0	0	109.3

Retrieved 498 of 498 residues in 1306.4 ms (Link to these results)

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