A0A087Y5J5_POEFO Loading...

Phosphatidylinositol transfer protein beta isoform

AlphaFold DB , UniProt , Accession A0A087Y5J5, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 271 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1E65.6Low93.2Very high207 Ų20740.5 Ų40.597%0.96720%0.198SC*.  0165.70-73.4166.7131.900109
2L81.4Confident93.5Very high91 Ų9137.7 Ų37.748%0.47619%0.185SC..  trans-80.8139.8172-66.9171.4000109.1L4 F108 T197 K199L2-L4 HydrophobicContact CB-CD1 3.54Å; L2-L4 WeakPolarHBondContact O-CD1 3.31Å; L2-F108 HydrophobicContact CD2-CE1 4.27Å; L2-F108 HydrophobicContact CD2-CZ 3.74Å; L2-T197 HydrophobicContact CB-CG2 4.14Å; L2-T197 HydrophobicContact CD1-CG2 4.2Å; L2-T197 HydrophobicContact CD2-CG2 4.4Å; L2-T197 HydrophobicContact CG-CG2 4.49Å; L2-K199 HydrophobicContact CD2-CB 3.75Å; L2-K199 HydrophobicContact CD2-CD 4.14Å; L2-K199 HydrophobicContact CD2-CG 4.02Å
3C90.8Very high93.8Very high26 Ų2635.1 Ų35.118%0.17617%0.173CC..EExtended strand (participates in β ladder)trans-94.6110.6177.8-172.30000110.1V198 E210 H214C3-V198 PolarHBondContact N-O 3.18Å; C3-V198 VanDerWaalsContact N-O 3.17Å; C3-V198 PolarHBondContact O-N 2.81Å; C3-E210 HydrophobicContact CB-CB 4.08Å; C3-E210 HydrophobicContact CB-CG 4.4Å; C3-H214 PolarHBondContact O-NE2 2.7Å; C3-H214 PolarHBondContact SG-CD2 3.31Å; C3-H214 PolarHBondContact SG-NE2 2.95Å; C3-H214 VanDerWaalsContact SG-NE2 3.4Å
4L97.1Very high94Very high25 Ų2534 Ų3413%0.13117%0.171CC..EExtended strand (participates in β ladder)trans-113.8135.5-177.5-74.777.5000111.9L2 I132 V136 L195 V196 T197L2-L4 HydrophobicContact CB-CD1 3.54Å; L2-L4 WeakPolarHBondContact O-CD1 3.31Å; L4-I132 HydrophobicContact CD2-CG2 3.98Å; L4-V136 HydrophobicContact CB-CG2 3.89Å; L4-V136 HydrophobicContact CD2-CG2 4.24Å; L4-L195 HydrophobicContact CD2-CD1 4.36Å; L4-V196 VanDerWaalsContact CA-O 3.3Å; L4-V196 WeakPolarHBondContact CA-O 3.49Å; L4-T197 HydrophobicContact CD1-CG2 3.85Å; L4-T197 HydrophobicContact CG-CG2 4.02Å
5K98.4Very high94.3Very high51 Ų5134 Ų3422%0.22217%0.171CC..EExtended strand (participates in β ladder)trans-138142.7168.7-59.5-172.9-171.91750109.5A137 V139 V196 H214K5-A137 CarbonylContact C-O 3.52Å; K5-A137 WeakPolarHBondContact CA-O 3.23Å; K5-A137 HydrophobicContact CG-CB 4.29Å; K5-V139 HydrophobicContact CB-CG2 4.35Å; K5-V139 HydrophobicContact CD-CG2 4.33Å; K5-V196 PolarHBondContact N-O 3.06Å; K5-V196 PolarHBondContact O-N 2.65Å; K5-H214 HydrophobicContact CD-CB 3.95Å
6Q98.6Very high94.5Very high0 Ų039.3 Ų39.30%020%0.195CC..EExtended strand (participates in β ladder)trans-109.1109.5175.2-170.4-176.6-100.200110R8 H126 V136 A137 V138 V139 K194 L195Q6-R8 VanDerWaalsContact NE2-NE 3.12Å; Q6-H126 PolarHBondContact OE1-ND1 3.02Å; Q6-V136 HydrophobicContact CB-CG1 4.05Å; Q6-A137 PolarHBondContact N-O 3.18Å; Q6-V138 WeakPolarHBondContact O-CA 3.17Å; Q6-V139 PolarHBondContact O-N 2.79Å; Q6-K194 CarbonylContact C-O 3.51Å; Q6-K194 WeakPolarHBondContact CA-O 3.49Å; Q6-L195 HydrophobicContact CB-CD1 4.08Å
7N98.8Very high94.7Very high3 Ų339.5 Ų39.52%0.01620%0.195CC..EExtended strand (participates in β ladder)trans-82.9128.9174-62.1-86.9000109.5V139 I141 K194 F221N7-V139 CarbonylContact C-O 3.59Å; N7-V139 VanDerWaalsContact CA-O 3.25Å; N7-V139 WeakPolarHBondContact CA-O 3.48Å; N7-V139 WeakPolarHBondContact OD1-CB 3.23Å; N7-V139 WeakPolarHBondContact OD1-CG1 3.46Å; N7-I141 HydrophobicContact CB-CD1 4.02Å; N7-K194 HydrophobicContact CB-CB 4.35Å; N7-K194 PolarHBondContact N-O 3.12Å; N7-K194 PolarHBondContact O-N 3.13Å; N7-F221 HydrophobicContact CB-CD2 3.86Å; N7-F221 HydrophobicContact CB-CE2 4.17Å
8R98.7Very high94.9Very high28 Ų2837.3 Ų37.311%0.10618%0.184CC..EExtended strand (participates in β ladder)trans-111.8116.9177.1-67.2-174.6-179.6165.47.9109.2Q6 G120 Q122 E123 V138 V139 I141 A192 Y193Q6-R8 VanDerWaalsContact NE2-NE 3.12Å; R8-G120 WeakPolarHBondContact CD-O 3.27Å; R8-G120 PolarHBondContact NH1-O 3Å; R8-Q122 PolarHBondContact NH2-O 3.31Å; R8-E123 IonicContact CZ-OE1 3.95Å; R8-E123 VanDerWaalsContact CZ-OE1 3.29Å; R8-E123 IonicContact NH1-OE1 3.48Å; R8-E123 PolarHBondContact NH1-OE1 2.78Å; R8-E123 IonicContact NH2-OE1 3.65Å; R8-E123 PolarHBondContact NH2-OE1 2.87Å; R8-E123 IonicContact NH2-OE2 3.8Å; R8-E123 PolarHBondContact NH2-OE2 3.08Å; R8-E123 VanDerWaalsContact NH2-OE2 3.08Å; R8-V138 HydrophobicContact CG-CG1 4.11Å; R8-V139 PolarHBondContact N-O 2.95Å; R8-I141 PolarHBondContact O-N 2.91Å; R8-A192 WeakPolarHBondContact CA-O 3.25Å; R8-Y193 HydrophobicContact CG-CD1 3.95Å; R8-Y193 HydrophobicContact CG-CE1 4.17Å
9V98.8Very high95.1Very high0 Ų038.6 Ų38.60%019%0.19CC..EExtended strand (participates in β ladder)trans-114.4104.3178.8-161.40000109.1L11 I141 I143 C191 A192 H225V9-L11 HydrophobicContact CG1-CD2 3.96Å; V9-L11 HydrophobicContact CG1-CG 4.2Å; V9-I141 HydrophobicContact CG1-CB 4.46Å; V9-I141 HydrophobicContact CG1-CG2 4.31Å; V9-I141 HydrophobicContact CG2-CB 4.09Å; V9-I141 HydrophobicContact CG2-CD1 4.06Å; V9-I141 HydrophobicContact CG2-CG1 4.49Å; V9-I141 HydrophobicContact CG2-CG2 4.49Å; V9-I143 HydrophobicContact CG1-CG2 4.12Å; V9-C191 CarbonylContact O-C 3.2Å; V9-C191 WeakPolarHBondContact O-CA 3.36Å; V9-A192 HydrophobicContact CB-CB 4.33Å; V9-A192 PolarHBondContact N-O 3.35Å; V9-A192 PolarHBondContact O-N 3.41Å; V9-H225 HydrophobicContact CG1-CB 3.96Å
10V98.6Very high95.2Very high12 Ų1237.6 Ų37.67%0.07319%0.186CC..EExtended strand (participates in β ladder)trans-79.1140.2171.51760000108.4M119 W177 L181 M190 C191V10-M119 HydrophobicContact CG1-CE 3.66Å; V10-M119 HydrophobicContact CG1-SD 3.96Å; V10-M119 WeakPolarHBondContact CG2-O 3.46Å; V10-W177 HydrophobicContact CB-CH2 4.34Å; V10-W177 HydrophobicContact CG1-CH2 4.05Å; V10-W177 HydrophobicContact CG1-CZ3 4.34Å; V10-W177 WeakPolarHBondContact O-CH2 3.38Å; V10-L181 HydrophobicContact CG1-CD2 4.36Å; V10-M190 WeakPolarHBondContact CA-O 3.38Å; V10-C191 HydrophobicContact CG2-CB 4.29Å
11L98.6Very high95.4Very high2 Ų235.8 Ų35.81%0.0118%0.177CC..EExtended strand (participates in β ladder)trans-139.3143.2-177.4-61.7168.9000111.9V9 C13 Y18 I143 M190 H225V9-L11 HydrophobicContact CG1-CD2 3.96Å; V9-L11 HydrophobicContact CG1-CG 4.2Å; L11-C13 PolarHBondContact O-N 3.45Å; L11-Y18 HydrophobicContact CD1-CD2 3.42Å; L11-Y18 VanDerWaalsContact CD1-CD2 3.42Å; L11-Y18 HydrophobicContact CD1-CE2 3.28Å; L11-I143 HydrophobicContact CD2-CD1 3.82Å; L11-I143 HydrophobicContact CD2-CG2 4.26Å; L11-M190 HydrophobicContact CB-CG 4.2Å; L11-M190 HydrophobicContact CB-SD 4.47Å; L11-M190 HydrophobicContact CD1-CE 4.28Å; L11-M190 HydrophobicContact CD1-SD 4.03Å; L11-M190 PolarHBondContact N-O 2.55Å; L11-M190 PolarHBondContact O-N 3.37Å; L11-H225 HydrophobicContact CD2-CB 4.12Å
12P97.2Very high96.9Very high7 Ų727.2 Ų27.25%0.04514%0.137CC..SBendtrans-82.853.4174.537.3-37.8000111.6R170 L173 W177 L181 P188 F229P12-R170 WeakPolarHBondContact O-CD 3.32Å; P12-R170 PolarHBondContact O-NH1 3.11Å; P12-L173 HydrophobicContact CG-CD1 4.36Å; P12-L173 HydrophobicContact CG-CD2 4.21Å; P12-W177 HydrophobicContact CB-CZ3 4.33Å; P12-W177 HydrophobicContact CG-CZ3 4.29Å; P12-L181 HydrophobicContact CB-CD1 4.36Å; P12-L181 HydrophobicContact CB-CD2 4.08Å; P12-P188 CarbonylContact C-O 2.92Å; P12-P188 VanDerWaalsContact C-O 3.28Å; P12-F229 HydrophobicContact CB-CE2 4.43Å; P12-F229 HydrophobicContact CG-CD2 3.57Å; P12-F229 HydrophobicContact CG-CE2 3.33Å; P12-F229 HydrophobicContact CG-CZ 4.26Å
13C96.8Very high97.7Very high4 Ų423.8 Ų23.83%0.02712%0.119CC..SBendtrans-143.8165.2173.966.40000110.3L11 E17 P188 K189 M190L11-C13 PolarHBondContact O-N 3.45Å; C13-E17 VanDerWaalsContact CA-OE2 3.24Å; C13-E17 WeakPolarHBondContact CA-OE2 3.36Å; C13-E17 HydrophobicContact CB-CB 4.12Å; C13-E17 WeakPolarHBondContact CB-OE2 3.27Å; C13-P188 PolarHBondContact N-O 3.43Å; C13-P188 CarbonylContact O-C 3.59Å; C13-K189 CarbonylContact O-C 3.57Å; C13-K189 WeakPolarHBondContact O-CA 3.21Å; C13-K189 PolarHBondContact O-N 3.16Å; C13-M190 WeakPolarHBondContact O-CG 3.42Å; C13-M190 PolarHBondContact O-N 2.63Å
14S97.5Very high98Very high20 Ų2023.2 Ų23.214%0.1411%0.114CC..  trans-80.1169.4174.3910000110.8E16 E17 Y18S14-E16 VanDerWaalsContact C-N 3.28Å; S14-E16 VanDerWaalsContact CB-OE2 3.26Å; S14-E16 WeakPolarHBondContact CB-OE2 3.43Å; S14-E16 PolarHBondContact OG-N 2.93Å; S14-E16 VanDerWaalsContact OG-N 3.16Å; S14-E16 PolarHBondContact OG-OE2 3.01Å; S14-E17 PolarHBondContact N-OE2 3.46Å; S14-E17 PolarHBondContact OG-N 3.17Å; S14-Y18 WeakPolarHBondContact O-CB 3.43Å; S14-Y18 PolarHBondContact O-N 2.81Å
15I97.5Very high98Very high34 Ų3422 Ų2217%0.17411%0.107CC..Hα-helixtrans-67.6-32.6173.262177.8000111Q19 Y91 P117 M190I15-Q19 PolarHBondContact O-N 2.53Å; I15-Y91 WeakPolarHBondContact CA-OH 3.43Å; I15-Y91 HydrophobicContact CB-CE1 4.43Å; I15-Y91 VanDerWaalsContact O-CE1 3.23Å; I15-Y91 WeakPolarHBondContact O-CE1 3.36Å; I15-Y91 PolarHBondContact O-OH 3.31Å; I15-P117 HydrophobicContact CG2-CB 4.25Å; I15-M190 HydrophobicContact CG2-CB 3.78Å
16E97.4Very high97.9Very high119 Ų11921.6 Ų21.656%0.55611%0.109SC*.Hα-helixtrans-69.7-45.7177.3-58.273.2-15900110.8S14 Y18 Q19S14-E16 VanDerWaalsContact C-N 3.28Å; S14-E16 VanDerWaalsContact CB-OE2 3.26Å; S14-E16 WeakPolarHBondContact CB-OE2 3.43Å; S14-E16 PolarHBondContact OG-N 2.93Å; S14-E16 VanDerWaalsContact OG-N 3.16Å; S14-E16 PolarHBondContact OG-OE2 3.01Å; E16-Y18 VanDerWaalsContact C-N 3.34Å; E16-Y18 PolarHBondContact O-N 2.96Å; E16-Q19 WeakPolarHBondContact O-CB 3.25Å; E16-Q19 PolarHBondContact O-N 2.72Å
17E98.1Very high97.7Very high43 Ų4322 Ų2220%0.20111%0.112CC..Hα-helixtrans-60.2-44.2174.7-72.1176.7154.100111.4C13 S14 Q19 V20 G21 R170 W235C13-E17 VanDerWaalsContact CA-OE2 3.24Å; C13-E17 WeakPolarHBondContact CA-OE2 3.36Å; C13-E17 HydrophobicContact CB-CB 4.12Å; C13-E17 WeakPolarHBondContact CB-OE2 3.27Å; S14-E17 PolarHBondContact N-OE2 3.46Å; S14-E17 PolarHBondContact OG-N 3.17Å; E17-Q19 VanDerWaalsContact C-N 3.26Å; E17-Q19 PolarHBondContact O-N 2.94Å; E17-V20 PolarHBondContact O-N 3.03Å; E17-G21 PolarHBondContact O-N 2.85Å; E17-R170 IonicContact OE1-CZ 3.42Å; E17-R170 IonicContact OE1-NH1 3.36Å; E17-R170 PolarHBondContact OE1-NH1 3.15Å; E17-R170 IonicContact OE1-NH2 3.11Å; E17-R170 PolarHBondContact OE1-NH2 2.83Å; E17-R170 IonicContact OE2-CZ 3.51Å; E17-R170 IonicContact OE2-NH1 2.74Å; E17-R170 PolarHBondContact OE2-NH1 3.14Å; E17-R170 IonicContact OE2-NH2 2.84Å; E17-R170 PolarHBondContact OE2-NH2 2.94Å; E17-W235 HydrophobicContact CB-CH2 4.25Å; E17-W235 HydrophobicContact CB-CZ3 3.96Å; E17-W235 VanDerWaalsContact O-CZ3 3.31Å; E17-W235 WeakPolarHBondContact O-CZ3 3.39Å
18Y98.5Very high97.5Very high0 Ų023.9 Ų23.90%012%0.121CC..Hα-helixtrans-61.5-34.3179.3-175-90.8000112.3L11 S14 E16 V20 G21 Q22 Y91 H115 M190 K194 H225 L228L11-Y18 HydrophobicContact CD1-CD2 3.42Å; L11-Y18 VanDerWaalsContact CD1-CD2 3.42Å; L11-Y18 HydrophobicContact CD1-CE2 3.28Å; S14-Y18 WeakPolarHBondContact O-CB 3.43Å; S14-Y18 PolarHBondContact O-N 2.81Å; E16-Y18 VanDerWaalsContact C-N 3.34Å; E16-Y18 PolarHBondContact O-N 2.96Å; Y18-V20 VanDerWaalsContact C-N 3.29Å; Y18-V20 PolarHBondContact O-N 3.26Å; Y18-G21 PolarHBondContact O-N 3.29Å; Y18-Q22 HydrophobicContact CD1-CB 4.11Å; Y18-Q22 HydrophobicContact CE1-CB 3.76Å; Y18-Q22 HydrophobicContact CE1-CG 4.02Å; Y18-Q22 WeakPolarHBondContact O-CB 3.28Å; Y18-Q22 PolarHBondContact O-N 2.99Å; Y18-Y91 HydrophobicContact CD1-CE2 4.03Å; Y18-H115 AromaticContact CD1-CD2 3.54Å; Y18-H115 AromaticContact CD1-NE2 3.91Å; Y18-H115 AromaticContact CE1-CD2 3.2Å; Y18-H115 WeakPolarHBondContact CE1-CD2 3.45Å; Y18-H115 AromaticContact CE1-NE2 3.17Å; Y18-H115 WeakPolarHBondContact CE1-NE2 3.23Å; Y18-H115 AromaticContact CZ-CD2 3.97Å; Y18-H115 AromaticContact CZ-NE2 3.93Å; Y18-M190 VanDerWaalsContact CB-SD 3.54Å; Y18-M190 HydrophobicContact CD1-SD 4.22Å; Y18-M190 HydrophobicContact CD2-SD 3.62Å; Y18-M190 HydrophobicContact CE2-SD 4.37Å; Y18-M190 HydrophobicContact CG-SD 3.51Å; Y18-M190 VanDerWaalsContact CG-SD 3.51Å; Y18-K194 PolarHBondContact OH-NZ 2.87Å; Y18-H225 AromaticContact CE2-CD2 3.83Å; Y18-H225 AromaticContact CE2-NE2 3.85Å; Y18-H225 AromaticContact CZ-NE2 3.8Å; Y18-H225 PolarHBondContact OH-NE2 3.12Å; Y18-L228 HydrophobicContact CD2-CD1 4.08Å; Y18-L228 HydrophobicContact CE2-CD1 3.72Å
19Q98.1Very high97.1Very high61 Ų6123.5 Ų23.529%0.28512%0.124SC..Hα-helixtrans-58-44.5177.8-172.2177.98.800111.4I15 E16 E17 L23 Y91 M240I15-Q19 PolarHBondContact O-N 2.53Å; E16-Q19 WeakPolarHBondContact O-CB 3.25Å; E16-Q19 PolarHBondContact O-N 2.72Å; E17-Q19 VanDerWaalsContact C-N 3.26Å; E17-Q19 PolarHBondContact O-N 2.94Å; Q19-L23 WeakPolarHBondContact O-CD1 3.13Å; Q19-L23 WeakPolarHBondContact O-CG 3.47Å; Q19-Y91 HydrophobicContact CB-CD1 3.95Å; Q19-Y91 HydrophobicContact CB-CD2 4.41Å; Q19-Y91 HydrophobicContact CB-CE1 3.81Å; Q19-Y91 HydrophobicContact CB-CE2 4.29Å; Q19-Y91 HydrophobicContact CB-CG 4.25Å; Q19-Y91 HydrophobicContact CG-CD1 3.88Å; Q19-Y91 HydrophobicContact CG-CD2 4.23Å; Q19-Y91 HydrophobicContact CG-CE1 4.27Å; Q19-Y91 HydrophobicContact CG-CG 3.86Å; Q19-M240 HydrophobicContact CG-SD 4.22Å
20V98.2Very high96.8Very high18 Ų1823.8 Ų23.811%0.10913%0.126CC..Hα-helixtrans-72.3-51.1177176.60000110.5E17 Y18 Q22 L23 F24 L238 M240 I243E17-V20 PolarHBondContact O-N 3.03Å; Y18-V20 VanDerWaalsContact C-N 3.29Å; Y18-V20 PolarHBondContact O-N 3.26Å; V20-Q22 VanDerWaalsContact C-N 3.3Å; V20-Q22 PolarHBondContact O-N 3.22Å; V20-L23 PolarHBondContact O-N 3.12Å; V20-L23 VanDerWaalsContact O-N 3.17Å; V20-F24 PolarHBondContact O-N 3.25Å; V20-L238 HydrophobicContact CG1-CB 3.81Å; V20-L238 WeakPolarHBondContact CG1-O 3.17Å; V20-M240 HydrophobicContact CG2-SD 4.22Å; V20-I243 HydrophobicContact CG1-CD1 3.88Å; V20-I243 HydrophobicContact CG1-CG1 3.89Å
21G98.2Very high96.5Very high0 Ų024.7 Ų24.70%013%0.129CC..Hα-helixtrans-61.3-36.1-176.300000113.5E17 Y18 S25 W235E17-G21 PolarHBondContact O-N 2.85Å; Y18-G21 PolarHBondContact O-N 3.29Å; G21-S25 WeakPolarHBondContact O-CB 3.31Å; G21-S25 PolarHBondContact O-N 3.33Å; G21-S25 PolarHBondContact O-OG 3.31Å; G21-W235 VanDerWaalsContact CA-CE3 3.47Å
22Q98.2Very high96Very high28 Ų2827.7 Ų27.713%0.13115%0.145CC..Hα-helixtrans-63.5-48.4175-176.1-173.91700111.2Y18 V20 S25 V26 F224 L228Y18-Q22 HydrophobicContact CD1-CB 4.11Å; Y18-Q22 HydrophobicContact CE1-CB 3.76Å; Y18-Q22 HydrophobicContact CE1-CG 4.02Å; Y18-Q22 WeakPolarHBondContact O-CB 3.28Å; Y18-Q22 PolarHBondContact O-N 2.99Å; V20-Q22 VanDerWaalsContact C-N 3.3Å; V20-Q22 PolarHBondContact O-N 3.22Å; Q22-S25 PolarHBondContact O-N 2.88Å; Q22-V26 HydrophobicContact CG-CG2 4.42Å; Q22-V26 WeakPolarHBondContact O-CB 3.4Å; Q22-V26 VanDerWaalsContact O-CG2 3.25Å; Q22-V26 WeakPolarHBondContact O-CG2 3.24Å; Q22-V26 PolarHBondContact O-N 3.12Å; Q22-F224 HydrophobicContact CG-CE1 4.33Å; Q22-F224 HydrophobicContact CG-CZ 4.08Å; Q22-L228 HydrophobicContact CB-CD1 4.46Å
23L97.3Very high95.6Very high19 Ų1929.7 Ų29.710%0.09915%0.153CC..Hα-helixtrans-67-42.6-176.9-65.4172.1000111.4Q19 V20 V26 A27 M240 I243Q19-L23 WeakPolarHBondContact O-CD1 3.13Å; Q19-L23 WeakPolarHBondContact O-CG 3.47Å; V20-L23 PolarHBondContact O-N 3.12Å; V20-L23 VanDerWaalsContact O-N 3.17Å; L23-V26 PolarHBondContact O-N 3.41Å; L23-A27 PolarHBondContact O-N 3.24Å; L23-A27 VanDerWaalsContact O-N 3.13Å; L23-M240 HydrophobicContact CD1-CE 3.61Å; L23-M240 HydrophobicContact CD1-SD 4.16Å; L23-I243 HydrophobicContact CB-CG2 3.49Å; L23-I243 VanDerWaalsContact CB-CG2 3.49Å; L23-I243 HydrophobicContact CD1-CG2 3.69Å; L23-I243 HydrophobicContact CG-CG2 4.2Å
24F97.9Very high95.2Very high14 Ų1429.5 Ų29.56%0.06115%0.152CC..Hα-helixtrans-56.7-51.7171.4175.8-85.9000111.4V20 V26 A27 E28 W231 K234 W235 L238 I243 M246V20-F24 PolarHBondContact O-N 3.25Å; F24-V26 VanDerWaalsContact C-N 3.3Å; F24-V26 PolarHBondContact O-N 3.15Å; F24-A27 WeakPolarHBondContact O-CB 3.48Å; F24-A27 PolarHBondContact O-N 2.99Å; F24-A27 VanDerWaalsContact O-N 3.11Å; F24-E28 HydrophobicContact CD1-CG 4.22Å; F24-E28 HydrophobicContact CE1-CG 3.67Å; F24-E28 HydrophobicContact CE2-CG 4.4Å; F24-E28 HydrophobicContact CZ-CG 3.76Å; F24-E28 PolarHBondContact O-N 3.27Å; F24-W231 HydrophobicContact CE1-CB 4.12Å; F24-W231 HydrophobicContact CE1-CE3 4.21Å; F24-K234 HydrophobicContact CE1-CB 3.99Å; F24-K234 HydrophobicContact CE1-CD 4.31Å; F24-K234 HydrophobicContact CE2-CB 4.15Å; F24-K234 HydrophobicContact CZ-CB 3.52Å; F24-K234 HydrophobicContact CZ-CD 3.96Å; F24-K234 HydrophobicContact CZ-CG 4.4Å; F24-W235 HydrophobicContact CB-CB 3.75Å; F24-W235 HydrophobicContact CB-CG 4.34Å; F24-W235 HydrophobicContact CD1-CB 3.84Å; F24-W235 AromaticContact CD1-CD1 3.68Å; F24-W235 HydrophobicContact CD1-CG 4.11Å; F24-W235 HydrophobicContact CD2-CB 3.88Å; F24-W235 HydrophobicContact CE1-CB 4.45Å; F24-W235 HydrophobicContact CE2-CB 4.46Å; F24-W235 HydrophobicContact CG-CB 3.54Å; F24-W235 HydrophobicContact CG-CG 4.23Å; F24-L238 HydrophobicContact CD2-CD1 3.66Å; F24-L238 HydrophobicContact CE2-CD1 4.22Å; F24-I243 HydrophobicContact CB-CD1 3.95Å; F24-M246 HydrophobicContact CD2-CE 3.45Å; F24-M246 VanDerWaalsContact CD2-CE 3.45Å; F24-M246 HydrophobicContact CD2-SD 3.94Å; F24-M246 HydrophobicContact CE2-CE 3.56Å; F24-M246 HydrophobicContact CE2-SD 4.29Å
25S97.5Very high94.9Very high0 Ų028.6 Ų28.60%015%0.146CC..Hα-helixtrans-67.8-32.1-175.1-56.10000111.9G21 Q22 A29 L228G21-S25 WeakPolarHBondContact O-CB 3.31Å; G21-S25 PolarHBondContact O-N 3.33Å; G21-S25 PolarHBondContact O-OG 3.31Å; Q22-S25 PolarHBondContact O-N 2.88Å; S25-A29 WeakPolarHBondContact O-CB 3.42Å; S25-A29 PolarHBondContact O-N 2.82Å; S25-L228 WeakPolarHBondContact OG-CA 3.45Å
26V95.1Very high94.2Very high42 Ų4228.4 Ų28.426%0.25515%0.153SC..Hα-helixtrans-63.5-43.3172.7165.10000110.5Q22 L23 F24 S30 F224Q22-V26 HydrophobicContact CG-CG2 4.42Å; Q22-V26 WeakPolarHBondContact O-CB 3.4Å; Q22-V26 VanDerWaalsContact O-CG2 3.25Å; Q22-V26 WeakPolarHBondContact O-CG2 3.24Å; Q22-V26 PolarHBondContact O-N 3.12Å; L23-V26 PolarHBondContact O-N 3.41Å; F24-V26 VanDerWaalsContact C-N 3.3Å; F24-V26 PolarHBondContact O-N 3.15Å; V26-S30 VanDerWaalsContact O-CB 3.27Å; V26-S30 WeakPolarHBondContact O-CB 3.22Å; V26-S30 PolarHBondContact O-N 3.45Å; V26-S30 PolarHBondContact O-OG 3.41Å; V26-F224 HydrophobicContact CG2-CE2 3.74Å; V26-F224 HydrophobicContact CG2-CZ 3.84Å
27A94.3Very high93.5Very high7 Ų724.6 Ų24.66%0.05815%0.145CC..Hα-helixtrans-61.1-50.4177.600000111.4L23 F24 S30 K31 T250L23-A27 PolarHBondContact O-N 3.24Å; L23-A27 VanDerWaalsContact O-N 3.13Å; F24-A27 WeakPolarHBondContact O-CB 3.48Å; F24-A27 PolarHBondContact O-N 2.99Å; F24-A27 VanDerWaalsContact O-N 3.11Å; A27-S30 WeakPolarHBondContact O-CB 3.47Å; A27-S30 PolarHBondContact O-N 3.4Å; A27-K31 WeakPolarHBondContact O-CG 3.19Å; A27-K31 PolarHBondContact O-N 2.85Å; A27-T250 HydrophobicContact CB-CG2 3.98Å
28E94.8Very high93.1Very high44 Ų4423.1 Ų23.121%0.20614%0.138CC..Hα-helixtrans-66.5-44.3-179.3-68.3-65.210900112.6F24 S30 K31 N32 W231F24-E28 HydrophobicContact CD1-CG 4.22Å; F24-E28 HydrophobicContact CE1-CG 3.67Å; F24-E28 HydrophobicContact CE2-CG 4.4Å; F24-E28 HydrophobicContact CZ-CG 3.76Å; F24-E28 PolarHBondContact O-N 3.27Å; E28-S30 VanDerWaalsContact C-N 3.26Å; E28-S30 PolarHBondContact O-N 3.01Å; E28-K31 PolarHBondContact O-N 3.48Å; E28-K31 VanDerWaalsContact O-N 3.17Å; E28-K31 IonicContact OE1-NZ 2.63Å; E28-K31 PolarHBondContact OE1-NZ 3.22Å; E28-K31 VanDerWaalsContact OE1-NZ 3.11Å; E28-N32 PolarHBondContact O-N 3.12Å; E28-N32 VanDerWaalsContact O-N 3.08Å; E28-N32 PolarHBondContact O-ND2 3.35Å; E28-W231 HydrophobicContact CB-CE3 4.27Å; E28-W231 HydrophobicContact CB-CH2 4.04Å; E28-W231 HydrophobicContact CB-CZ3 3.7Å
29A91.8Very high92.6Very high20 Ų2023.2 Ų23.217%0.16514%0.139CC..Hα-helixtrans-61.5-36.817500000111.5S25 K31 N32 E33 F224S25-A29 WeakPolarHBondContact O-CB 3.42Å; S25-A29 PolarHBondContact O-N 2.82Å; A29-K31 VanDerWaalsContact C-N 3.32Å; A29-K31 PolarHBondContact O-N 2.73Å; A29-N32 PolarHBondContact O-N 2.94Å; A29-E33 WeakPolarHBondContact O-CG 3.27Å; A29-E33 PolarHBondContact O-N 3.44Å; A29-E33 VanDerWaalsContact O-N 3.09Å; A29-F224 HydrophobicContact CB-CD2 4.49Å
30S91.3Very high92.4Very high6 Ų621.3 Ų21.34%0.04213%0.131CC..Hα-helixtrans-61.8-40.6176.3-59.10000112V26 A27 E28 E33 T34 I40 L254V26-S30 VanDerWaalsContact O-CB 3.27Å; V26-S30 WeakPolarHBondContact O-CB 3.22Å; V26-S30 PolarHBondContact O-N 3.45Å; V26-S30 PolarHBondContact O-OG 3.41Å; A27-S30 WeakPolarHBondContact O-CB 3.47Å; A27-S30 PolarHBondContact O-N 3.4Å; E28-S30 VanDerWaalsContact C-N 3.26Å; E28-S30 PolarHBondContact O-N 3.01Å; S30-E33 PolarHBondContact O-N 3.42Å; S30-T34 WeakPolarHBondContact O-CB 3.49Å; S30-T34 PolarHBondContact O-N 2.9Å; S30-T34 PolarHBondContact O-OG1 3.25Å; S30-I40 WeakPolarHBondContact OG-CD1 3.5Å; S30-L254 VanDerWaalsContact C-CD2 3.49Å; S30-L254 WeakPolarHBondContact O-CD2 3.47Å
31K91.9Very high92.2Very high31 Ų3122.8 Ų22.814%0.13514%0.136CC..Hα-helixtrans-65.7-43177.5-64.5171.9-168.7-173.70111.5A27 E28 A29 E33 T34 T250 E253 L254 L257A27-K31 WeakPolarHBondContact O-CG 3.19Å; A27-K31 PolarHBondContact O-N 2.85Å; E28-K31 PolarHBondContact O-N 3.48Å; E28-K31 VanDerWaalsContact O-N 3.17Å; E28-K31 IonicContact OE1-NZ 2.63Å; E28-K31 PolarHBondContact OE1-NZ 3.22Å; E28-K31 VanDerWaalsContact OE1-NZ 3.11Å; A29-K31 VanDerWaalsContact C-N 3.32Å; A29-K31 PolarHBondContact O-N 2.73Å; K31-E33 PolarHBondContact O-N 3.2Å; K31-T34 PolarHBondContact O-N 3.19Å; K31-T250 VanDerWaalsContact CE-OG1 3.27Å; K31-T250 WeakPolarHBondContact CE-OG1 3.35Å; K31-T250 HydrophobicContact CG-CG2 4.21Å; K31-E253 WeakPolarHBondContact CD-OE2 3.32Å; K31-E253 WeakPolarHBondContact CE-OE2 3.18Å; K31-E253 IonicContact NZ-OE2 2.68Å; K31-E253 PolarHBondContact NZ-OE2 2.93Å; K31-L254 HydrophobicContact CB-CD2 4.46Å; K31-L254 HydrophobicContact CG-CD2 4.05Å; K31-L257 HydrophobicContact CB-CD1 4.37Å
32N89.3Confident92Very high65 Ų6523.9 Ų23.935%0.34814%0.143SC..Hα-helixtrans-62.6-28177.8-69.7-22000112.9E28 A29 G265E28-N32 PolarHBondContact O-N 3.12Å; E28-N32 VanDerWaalsContact O-N 3.08Å; E28-N32 PolarHBondContact O-ND2 3.35Å; A29-N32 PolarHBondContact O-N 2.94Å; N32-G265 WeakPolarHBondContact O-CA 3.46Å
33E88Confident91.9Very high48 Ų4826 Ų2622%0.22416%0.155CC..THydrogen-bonded Turntrans-95.6-0.1-179.6-67.7-60.2154.100114.5A29 S30 K31 G39 K67 G265 T266A29-E33 WeakPolarHBondContact O-CG 3.27Å; A29-E33 PolarHBondContact O-N 3.44Å; A29-E33 VanDerWaalsContact O-N 3.09Å; S30-E33 PolarHBondContact O-N 3.42Å; K31-E33 PolarHBondContact O-N 3.2Å; E33-G39 VanDerWaalsContact O-CA 3.26Å; E33-G39 WeakPolarHBondContact O-CA 3.46Å; E33-K67 PolarHBondContact O-NZ 3.37Å; E33-K67 IonicContact OE2-NZ 3.37Å; E33-K67 PolarHBondContact OE2-NZ 2.92Å; E33-G265 WeakPolarHBondContact OE2-CA 3.37Å; E33-T266 VanDerWaalsContact CD-N 3.25Å; E33-T266 WeakPolarHBondContact OE1-CB 3.3Å; E33-T266 PolarHBondContact OE1-N 2.97Å; E33-T266 PolarHBondContact OE1-OG1 3.35Å; E33-T266 PolarHBondContact OE2-N 3.11Å
34T89.1Confident91.8Very high0 Ų029.5 Ų29.50%017%0.169CC..  trans-116.3125.1-172.9-56.80000112.2S30 K31 E38 I40 L254 L257 R258 R264S30-T34 WeakPolarHBondContact O-CB 3.49Å; S30-T34 PolarHBondContact O-N 2.9Å; S30-T34 PolarHBondContact O-OG1 3.25Å; K31-T34 PolarHBondContact O-N 3.19Å; T34-E38 WeakPolarHBondContact CA-O 3.5Å; T34-I40 PolarHBondContact OG1-N 3.38Å; T34-L254 HydrophobicContact CG2-CD2 4.14Å; T34-L257 HydrophobicContact CG2-CB 4.32Å; T34-R258 HydrophobicContact CG2-CB 3.82Å; T34-R258 HydrophobicContact CG2-CG 4.46Å; T34-R264 PolarHBondContact O-NE 2.84Å; T34-R264 PolarHBondContact O-NH2 3.3Å
35G89.8Confident91.6Very high2 Ų231 Ų312%0.02118%0.178CC..BIsolated β-bridgetrans175.2149.3-176.200000112.3G37 E38 L257 E262G35-G37 VanDerWaalsContact C-N 3.32Å; G35-G37 PolarHBondContact O-N 2.78Å; G35-E38 PolarHBondContact N-O 2.84Å; G35-E38 PolarHBondContact O-N 2.83Å; G35-E38 VanDerWaalsContact O-N 3.07Å; G35-L257 WeakPolarHBondContact CA-O 3.32Å; G35-E262 CarbonylContact C-O 3.53Å; G35-E262 WeakPolarHBondContact CA-O 3.22Å
36G83.5Confident91.5Very high30 Ų3034.9 Ų34.931%0.30920%0.196SC..THydrogen-bonded Turntrans59.935.7167.700000115.1E38 Q260 G261 E262G36-E38 VanDerWaalsContact C-N 3.35Å; G36-Q260 PolarHBondContact N-O 3.46Å; G36-G261 WeakPolarHBondContact CA-O 3.47Å; G36-E262 PolarHBondContact N-O 3.11Å
37G83.5Confident91.5Very high38 Ų3837.9 Ų37.939%0.39222%0.216SC..THydrogen-bonded Turntrans88.8-9.3-178.900000115.3G35 R258G35-G37 VanDerWaalsContact C-N 3.32Å; G35-G37 PolarHBondContact O-N 2.78Å; G37-R258 WeakPolarHBondContact CA-O 3.43Å; G37-R258 PolarHBondContact N-O 2.53Å
38E88.5Confident91.6Very high13 Ų1339.1 Ų39.16%0.06122%0.22CC..BIsolated β-bridgetrans-114.8164.7-177.8-68.1-169.8-13200112.6T34 G35 G36 H63 N65 S66 K67 V263T34-E38 WeakPolarHBondContact CA-O 3.5Å; G35-E38 PolarHBondContact N-O 2.84Å; G35-E38 PolarHBondContact O-N 2.83Å; G35-E38 VanDerWaalsContact O-N 3.07Å; G36-E38 VanDerWaalsContact C-N 3.35Å; E38-H63 WeakPolarHBondContact CA-O 3.36Å; E38-H63 WeakPolarHBondContact CB-O 3.37Å; E38-N65 HydrophobicContact CG-CB 4.3Å; E38-N65 PolarHBondContact OE2-N 2.85Å; E38-S66 WeakPolarHBondContact OE1-CB 3.4Å; E38-S66 PolarHBondContact OE1-N 2.99Å; E38-S66 PolarHBondContact OE1-OG 3.43Å; E38-S66 PolarHBondContact OE2-N 2.64Å; E38-S66 PolarHBondContact OE2-OG 3.32Å; E38-K67 WeakPolarHBondContact OE2-CG 3.38Å; E38-K67 PolarHBondContact OE2-N 2.7Å; E38-V263 HydrophobicContact CB-CG2 4.48Å; E38-V263 HydrophobicContact CG-CG2 4.4Å
39G89.6Confident91.6Very high2 Ų243.1 Ų43.12%0.02124%0.238CC..EExtended strand (participates in β ladder)trans107.9-141.8179.900000113.8E33 H63E33-G39 VanDerWaalsContact O-CA 3.26Å; E33-G39 WeakPolarHBondContact O-CA 3.46Å; G39-H63 PolarHBondContact N-O 2.85Å; G39-H63 PolarHBondContact O-N 2.75Å
40I93.1Very high91.6Very high21 Ų2148.6 Ų48.611%0.10826%0.258CS..EExtended strand (participates in β ladder)trans-108.6128.8-163.6-54.7-172.7000110.8S30 T34 V42 K60 I61 Y62 L254S30-I40 WeakPolarHBondContact OG-CD1 3.5Å; T34-I40 PolarHBondContact OG1-N 3.38Å; I40-V42 HydrophobicContact CG2-CG2 4.47Å; I40-K60 HydrophobicContact CG2-CB 4.34Å; I40-K60 HydrophobicContact CG2-CD 3.97Å; I40-I61 WeakPolarHBondContact CA-O 3.45Å; I40-Y62 HydrophobicContact CB-CD1 4.42Å; I40-Y62 HydrophobicContact CB-CE1 4.44Å; I40-Y62 HydrophobicContact CD1-CD1 4.28Å; I40-Y62 HydrophobicContact CD1-CE1 3.78Å; I40-Y62 HydrophobicContact CG1-CD1 3.82Å; I40-Y62 HydrophobicContact CG1-CE1 3.81Å; I40-Y62 HydrophobicContact CG2-CD1 4.29Å; I40-Y62 HydrophobicContact CG2-CE1 4.01Å; I40-L254 HydrophobicContact CG2-CD1 4.43Å
41E93.8Very high91.6Very high48 Ų4855.7 Ų55.722%0.22430%0.296CS..EExtended strand (participates in β ladder)trans-116.4127.7170.1172.9175.7-167.100109.4L43 K60 I61 H63 R258E41-L43 HydrophobicContact CG-CD2 4.05Å; E41-K60 CarbonylContact O-C 3.49Å; E41-K60 WeakPolarHBondContact O-CA 3.33Å; E41-K60 WeakPolarHBondContact O-CB 3.2Å; E41-I61 HydrophobicContact CB-CB 4.29Å; E41-I61 PolarHBondContact N-O 3.45Å; E41-I61 PolarHBondContact O-N 3.08Å; E41-H63 IonicContact OE2-CD2 3.72Å; E41-H63 IonicContact OE2-CE1 2.71Å; E41-H63 PolarHBondContact OE2-CE1 2.88Å; E41-H63 IonicContact OE2-NE2 2.64Å; E41-H63 PolarHBondContact OE2-NE2 3.32Å; E41-R258 IonicContact OE1-NH2 3.95Å; E41-R258 IonicContact OE2-CZ 3.52Å; E41-R258 IonicContact OE2-NE 2.78Å; E41-R258 IonicContact OE2-NH2 3.45Å; E41-R258 PolarHBondContact OE2-NH2 3.41Å
42V94.4Very high91.5Very high24 Ų2457.4 Ų57.415%0.14532%0.322CS..EExtended strand (participates in β ladder)trans-98.6112.2179.2-176.90000108.9I40 N45 K60 Q251 L254I40-V42 HydrophobicContact CG2-CG2 4.47Å; V42-N45 HydrophobicContact CG1-CB 4.32Å; V42-K60 HydrophobicContact CG2-CD 4.38Å; V42-K60 HydrophobicContact CG2-CG 4.22Å; V42-Q251 HydrophobicContact CB-CB 4.45Å; V42-Q251 HydrophobicContact CB-CG 4.05Å; V42-Q251 HydrophobicContact CG1-CG 4.42Å; V42-Q251 PolarHBondContact O-NE2 3.04Å; V42-L254 HydrophobicContact CG2-CD1 4Å
43L94.8Very high91.6Very high73 Ų7357.5 Ų57.538%0.38232%0.321SS..EExtended strand (participates in β ladder)trans-88.7-39.6178.8-63.9-174.8000112.6E41 H59 I61E41-L43 HydrophobicContact CG-CD2 4.05Å; L43-H59 WeakPolarHBondContact CA-O 3.4Å; L43-H59 HydrophobicContact CB-CB 4.48Å; L43-H59 WeakPolarHBondContact CB-O 3.36Å; L43-H59 PolarHBondContact N-O 3.43Å; L43-I61 HydrophobicContact CD1-CD1 3.52Å; L43-I61 HydrophobicContact CD1-CG1 3.8Å; L43-I61 HydrophobicContact CD2-CD1 4.32Å; L43-I61 HydrophobicContact CG-CD1 4.09Å; L43-I61 HydrophobicContact CG-CG1 4.18Å
44K95.2Very high92Very high92 Ų9261.4 Ų61.440%0.434%0.337SS..EExtended strand (participates in β ladder)trans-139.5140.1179.2-65.8179.8154.3-131.70110.3E46 Y57 T58 H59K44-E46 IonicContact NZ-OE1 3.7Å; K44-E46 PolarHBondContact NZ-OE1 3.46Å; K44-Y57 HydrophobicContact CB-CD1 4.42Å; K44-Y57 HydrophobicContact CB-CE1 4.17Å; K44-Y57 HydrophobicContact CD-CD1 4.5Å; K44-Y57 HydrophobicContact CD-CE1 3.83Å; K44-T58 CarbonylContact O-C 3.56Å; K44-T58 VanDerWaalsContact O-CA 3.24Å; K44-T58 WeakPolarHBondContact O-CA 3.35Å; K44-H59 HydrophobicContact CB-CB 3.97Å; K44-H59 HydrophobicContact CD-CB 4.44Å; K44-H59 HydrophobicContact CG-CB 4.39Å; K44-H59 PolarHBondContact N-O 3.4Å; K44-H59 VanDerWaalsContact N-O 3.11Å; K44-H59 PolarHBondContact O-N 3.07Å
45N94.4Very high92.3Very high46 Ų4662.4 Ų62.425%0.24635%0.348CS..EExtended strand (participates in β ladder)trans-146.393.9166.8-178.612.3000107.4V42 Q56 Y57 T58 E247V42-N45 HydrophobicContact CG1-CB 4.32Å; N45-Q56 WeakPolarHBondContact OD1-CG 3.5Å; N45-Q56 PolarHBondContact OD1-NE2 3.27Å; N45-Y57 WeakPolarHBondContact CA-O 3.41Å; N45-T58 HydrophobicContact CB-CG2 4.33Å; N45-E247 PolarHBondContact ND2-OE2 3.08Å
46E94.8Very high92.6Very high81 Ų8163.5 Ų63.538%0.37935%0.352SS..EExtended strand (participates in β ladder)trans-141147.7-171.461.5-168.6167.300111.4K44 Y57K44-E46 IonicContact NZ-OE1 3.7Å; K44-E46 PolarHBondContact NZ-OE1 3.46Å; E46-Y57 HydrophobicContact CG-CD1 4.19Å; E46-Y57 PolarHBondContact N-O 3.21Å; E46-Y57 PolarHBondContact O-N 3.41Å
47P95.7Very high93.2Very high104 Ų10463.5 Ų63.568%0.67534%0.343SS*.EExtended strand (participates in β ladder)trans-63.8149171.228.4-34.4000110.4G55P47-G55 CarbonylContact C-O 3.56Å; P47-G55 WeakPolarHBondContact CA-O 2.96Å
48Y96.6Very high93.9Very high34 Ų3462.7 Ų62.713%0.13333%0.331CS..EExtended strand (participates in β ladder)trans-132.9155172.979.9-81000111.7K50 E53 K54 G55 W88Y48-K50 HydrophobicContact CD2-CB 4.22Å; Y48-E53 HydrophobicContact CE2-CG 4.37Å; Y48-E53 WeakPolarHBondContact CE2-OE1 3.31Å; Y48-E53 PolarHBondContact OH-OE1 3.4Å; Y48-K54 WeakPolarHBondContact O-CA 3.27Å; Y48-G55 VanDerWaalsContact CD1-C 3.41Å; Y48-G55 WeakPolarHBondContact CD1-O 3.37Å; Y48-G55 VanDerWaalsContact CE1-C 3.43Å; Y48-G55 PolarHBondContact N-O 3.01Å; Y48-G55 PolarHBondContact O-N 2.84Å; Y48-G55 VanDerWaalsContact O-N 3.08Å; Y48-W88 HydrophobicContact CE1-CB 4.15Å; Y48-W88 AromaticContact CE2-CD1 3.87Å; Y48-W88 AromaticContact CZ-CD1 3.8Å
49E95.7Very high94.3Very high127 Ų12763.3 Ų63.359%0.59333%0.333SS*.EExtended strand (participates in β ladder)trans-136.7121.5168.8179164.7-177.800108.2E53 K54E49-E53 CarbonylContact C-O 3.6Å; E49-E53 VanDerWaalsContact CA-O 3.31Å; E49-E53 WeakPolarHBondContact CA-O 3.47Å; E49-K54 HydrophobicContact CB-CG 4.18Å; E49-K54 HydrophobicContact CG-CD 4.48Å; E49-K54 HydrophobicContact CG-CG 3.87Å; E49-K54 WeakPolarHBondContact OE1-CE 3.24Å; E49-K54 IonicContact OE1-NZ 3.98Å; E49-K54 PolarHBondContact OE1-NZ 3.37Å; E49-K54 WeakPolarHBondContact OE2-CE 3.34Å; E49-K54 IonicContact OE2-NZ 2.88Å; E49-K54 PolarHBondContact OE2-NZ 3.19Å
50K91.6Very high94.6Very high135 Ų13564.2 Ų64.259%0.58734%0.337SS*.EExtended strand (participates in β ladder)trans-148.1128.9179.9-175.2177.3177.5-177.20110.4Y48 G52 E53Y48-K50 HydrophobicContact CD2-CB 4.22Å; K50-G52 PolarHBondContact O-N 2.98Å; K50-G52 VanDerWaalsContact O-N 3.08Å; K50-E53 PolarHBondContact N-O 3.27Å; K50-E53 WeakPolarHBondContact O-CB 3.43Å; K50-E53 PolarHBondContact O-N 2.78Å
51D91.3Very high94.7Very high155 Ų15564.1 Ų64.183%0.82934%0.336SS*.THydrogen-bonded Turntrans5233.1176.4-54.1-38.9000113.6E53D51-E53 VanDerWaalsContact C-N 3.29Å; D51-E53 PolarHBondContact O-N 3.13Å
52G88.4Confident94.7Very high67 Ų6764.1 Ų64.169%0.69134%0.335SS*.THydrogen-bonded Turntrans82.8-7.4-17700000115.4K50K50-G52 PolarHBondContact O-N 2.98Å; K50-G52 VanDerWaalsContact O-N 3.08Å
53E92.5Very high94.5Very high67 Ų6764.5 Ų64.531%0.31334%0.335SS..EExtended strand (participates in β ladder)trans-83131.3170.5-170.5-177.681.700109.8Y48 E49 K50 D51 A90Y48-E53 HydrophobicContact CE2-CG 4.37Å; Y48-E53 WeakPolarHBondContact CE2-OE1 3.31Å; Y48-E53 PolarHBondContact OH-OE1 3.4Å; E49-E53 CarbonylContact C-O 3.6Å; E49-E53 VanDerWaalsContact CA-O 3.31Å; E49-E53 WeakPolarHBondContact CA-O 3.47Å; K50-E53 PolarHBondContact N-O 3.27Å; K50-E53 WeakPolarHBondContact O-CB 3.43Å; K50-E53 PolarHBondContact O-N 2.78Å; D51-E53 VanDerWaalsContact C-N 3.29Å; D51-E53 PolarHBondContact O-N 3.13Å; E53-A90 HydrophobicContact CG-CB 3.54Å
54K95.3Very high94.1Very high130 Ų13063.4 Ų63.457%0.56533%0.329SS*.EExtended strand (participates in β ladder)trans-121.6142.6176.4-61.1-176.8-165.8-124.90109.4Y48 E49 A90Y48-K54 WeakPolarHBondContact O-CA 3.27Å; E49-K54 HydrophobicContact CB-CG 4.18Å; E49-K54 HydrophobicContact CG-CD 4.48Å; E49-K54 HydrophobicContact CG-CG 3.87Å; E49-K54 WeakPolarHBondContact OE1-CE 3.24Å; E49-K54 IonicContact OE1-NZ 3.98Å; E49-K54 PolarHBondContact OE1-NZ 3.37Å; E49-K54 WeakPolarHBondContact OE2-CE 3.34Å; E49-K54 IonicContact OE2-NZ 2.88Å; E49-K54 PolarHBondContact OE2-NZ 3.19Å; K54-A90 WeakPolarHBondContact O-CB 3.32Å
55G95.8Very high93.4Very high22 Ų2263.7 Ų63.723%0.22734%0.335CS..EExtended strand (participates in β ladder)trans-178.6-161.3-179.400000113.1P47 Y48 N89P47-G55 CarbonylContact C-O 3.56Å; P47-G55 WeakPolarHBondContact CA-O 2.96Å; Y48-G55 VanDerWaalsContact CD1-C 3.41Å; Y48-G55 WeakPolarHBondContact CD1-O 3.37Å; Y48-G55 VanDerWaalsContact CE1-C 3.43Å; Y48-G55 PolarHBondContact N-O 3.01Å; Y48-G55 PolarHBondContact O-N 2.84Å; Y48-G55 VanDerWaalsContact O-N 3.08Å; G55-N89 CarbonylContact C-O 3.58Å; G55-N89 WeakPolarHBondContact CA-O 3.29Å
56Q96.1Very high92.7Very high24 Ų2463.4 Ų63.411%0.11234%0.337CS..EExtended strand (participates in β ladder)trans-106.5130.2172.8-161.474.513.600110.1N45 N89 R244N45-Q56 WeakPolarHBondContact OD1-CG 3.5Å; N45-Q56 PolarHBondContact OD1-NE2 3.27Å; Q56-N89 HydrophobicContact CB-CB 4.49Å; Q56-N89 PolarHBondContact N-O 2.72Å; Q56-N89 PolarHBondContact O-N 3.29Å; Q56-R244 VanDerWaalsContact OE1-NH2 3.15Å
57Y97.3Very high92.1Very high31 Ų3160.4 Ų60.412%0.12232%0.322CS..EExtended strand (participates in β ladder)trans-100.6131171.3173.1-101.6000109.4K44 N45 E46 H59 K86 A87 W88K44-Y57 HydrophobicContact CB-CD1 4.42Å; K44-Y57 HydrophobicContact CB-CE1 4.17Å; K44-Y57 HydrophobicContact CD-CD1 4.5Å; K44-Y57 HydrophobicContact CD-CE1 3.83Å; N45-Y57 WeakPolarHBondContact CA-O 3.41Å; E46-Y57 HydrophobicContact CG-CD1 4.19Å; E46-Y57 PolarHBondContact N-O 3.21Å; E46-Y57 PolarHBondContact O-N 3.41Å; Y57-H59 HydrophobicContact CE1-CB 3.99Å; Y57-K86 HydrophobicContact CE2-CB 4.14Å; Y57-K86 HydrophobicContact CE2-CG 4.48Å; Y57-K86 WeakPolarHBondContact OH-CD 3.45Å; Y57-K86 WeakPolarHBondContact OH-CG 3.4Å; Y57-A87 WeakPolarHBondContact CA-O 3.39Å; Y57-A87 WeakPolarHBondContact CD2-O 3.27Å; Y57-W88 AromaticContact CD2-CD1 3.85Å; Y57-W88 HydrophobicContact CD2-CD2 4.16Å; Y57-W88 AromaticContact CD2-CE2 3.7Å; Y57-W88 HydrophobicContact CD2-CG 4.26Å; Y57-W88 HydrophobicContact CD2-CZ2 4.18Å; Y57-W88 AromaticContact CD2-NE1 3.47Å; Y57-W88 HydrophobicContact CE2-CD2 4.35Å; Y57-W88 AromaticContact CE2-CE2 3.69Å; Y57-W88 HydrophobicContact CE2-CH2 4.29Å; Y57-W88 AromaticContact CE2-CZ2 3.67Å; Y57-W88 HydrophobicContact CE2-CZ2 3.67Å; Y57-W88 AromaticContact CE2-NE1 3.87Å
58T96.9Very high91.4Very high21 Ų2156.2 Ų56.213%0.12930%0.295CS..EExtended strand (participates in β ladder)trans-124.9141.3170.961.40000111.1K44 N45 K86 A87K44-T58 CarbonylContact O-C 3.56Å; K44-T58 VanDerWaalsContact O-CA 3.24Å; K44-T58 WeakPolarHBondContact O-CA 3.35Å; N45-T58 HydrophobicContact CB-CG2 4.33Å; T58-K86 WeakPolarHBondContact O-CA 3.42Å; T58-A87 PolarHBondContact N-O 2.81Å; T58-A87 PolarHBondContact O-N 3.5Å
59H97.4Very high90.5Very high25 Ų2554.7 Ų54.712%0.11629%0.289CS..EExtended strand (participates in β ladder)trans-123.4116167.8-176.2-172.8000108.1L43 K44 Y57 H84 E85 K86L43-H59 WeakPolarHBondContact CA-O 3.4Å; L43-H59 HydrophobicContact CB-CB 4.48Å; L43-H59 WeakPolarHBondContact CB-O 3.36Å; L43-H59 PolarHBondContact N-O 3.43Å; K44-H59 HydrophobicContact CB-CB 3.97Å; K44-H59 HydrophobicContact CD-CB 4.44Å; K44-H59 HydrophobicContact CG-CB 4.39Å; K44-H59 PolarHBondContact N-O 3.4Å; K44-H59 VanDerWaalsContact N-O 3.11Å; K44-H59 PolarHBondContact O-N 3.07Å; Y57-H59 HydrophobicContact CE1-CB 3.99Å; H59-H84 AromaticContact CE1-ND1 3.75Å; H59-H84 AromaticContact NE2-CG 3.88Å; H59-H84 AromaticContact NE2-ND1 3.15Å; H59-H84 PolarHBondContact NE2-ND1 3.16Å; H59-H84 VanDerWaalsContact NE2-ND1 3.15Å; H59-E85 CarbonylContact C-O 3.58Å; H59-E85 VanDerWaalsContact CA-O 3.32Å; H59-E85 WeakPolarHBondContact CA-O 3.5Å; H59-E85 PolarHBondContact CD2-O 3.47Å; H59-K86 HydrophobicContact CB-CG 4.48Å
60K96.3Very high89.7Confident22 Ų2250.6 Ų50.610%0.09628%0.281CS..EExtended strand (participates in β ladder)trans-119.2156.2177.2-53.7-179.5-175172.80111.2I40 E41 V42 Y62 E85I40-K60 HydrophobicContact CG2-CB 4.34Å; I40-K60 HydrophobicContact CG2-CD 3.97Å; E41-K60 CarbonylContact O-C 3.49Å; E41-K60 WeakPolarHBondContact O-CA 3.33Å; E41-K60 WeakPolarHBondContact O-CB 3.2Å; V42-K60 HydrophobicContact CG2-CD 4.38Å; V42-K60 HydrophobicContact CG2-CG 4.22Å; K60-Y62 HydrophobicContact CB-CE1 4.33Å; K60-E85 HydrophobicContact CB-CB 4.34Å; K60-E85 PolarHBondContact N-O 2.87Å; K60-E85 PolarHBondContact O-N 3.41Å
61I94.9Very high89Confident19 Ų1946.6 Ų46.610%0.09726%0.264CS..EExtended strand (participates in β ladder)trans-114.7131.7169.6-64.3-179.9000108.6I40 E41 L43 H63 V82 F83I40-I61 WeakPolarHBondContact CA-O 3.45Å; E41-I61 HydrophobicContact CB-CB 4.29Å; E41-I61 PolarHBondContact N-O 3.45Å; E41-I61 PolarHBondContact O-N 3.08Å; L43-I61 HydrophobicContact CD1-CD1 3.52Å; L43-I61 HydrophobicContact CD1-CG1 3.8Å; L43-I61 HydrophobicContact CD2-CD1 4.32Å; L43-I61 HydrophobicContact CG-CD1 4.09Å; L43-I61 HydrophobicContact CG-CG1 4.18Å; I61-H63 WeakPolarHBondContact CG2-NE2 3.48Å; I61-V82 HydrophobicContact CG2-CG1 3.33Å; I61-F83 CarbonylContact C-O 3.57Å; I61-F83 WeakPolarHBondContact CA-O 3.37Å
62Y93.3Very high88.3Confident48 Ų4840.4 Ų40.419%0.18823%0.232CC..EExtended strand (participates in β ladder)trans-102.5115.3170.9-56.8-33.9000110I40 K60 V82 F83 E85I40-Y62 HydrophobicContact CB-CD1 4.42Å; I40-Y62 HydrophobicContact CB-CE1 4.44Å; I40-Y62 HydrophobicContact CD1-CD1 4.28Å; I40-Y62 HydrophobicContact CD1-CE1 3.78Å; I40-Y62 HydrophobicContact CG1-CD1 3.82Å; I40-Y62 HydrophobicContact CG1-CE1 3.81Å; I40-Y62 HydrophobicContact CG2-CD1 4.29Å; I40-Y62 HydrophobicContact CG2-CE1 4.01Å; K60-Y62 HydrophobicContact CB-CE1 4.33Å; Y62-V82 WeakPolarHBondContact O-CA 3.47Å; Y62-F83 HydrophobicContact CD2-CB 4.49Å; Y62-F83 PolarHBondContact N-O 3.46Å; Y62-F83 PolarHBondContact O-N 2.87Å; Y62-E85 HydrophobicContact CD2-CB 4.46Å; Y62-E85 HydrophobicContact CE2-CB 3.79Å; Y62-E85 HydrophobicContact CE2-CG 4.39Å; Y62-E85 PolarHBondContact OH-OE1 2.57Å; Y62-E85 PolarHBondContact OH-OE2 3.21Å
63H91.3Very high87.9Confident32 Ų3241.5 Ų41.515%0.14822%0.215CC..EExtended strand (participates in β ladder)trans-95.7100.4176-60.5-83.1000108.5E38 G39 E41 I61E38-H63 WeakPolarHBondContact CA-O 3.36Å; E38-H63 WeakPolarHBondContact CB-O 3.37Å; G39-H63 PolarHBondContact N-O 2.85Å; G39-H63 PolarHBondContact O-N 2.75Å; E41-H63 IonicContact OE2-CD2 3.72Å; E41-H63 IonicContact OE2-CE1 2.71Å; E41-H63 PolarHBondContact OE2-CE1 2.88Å; E41-H63 IonicContact OE2-NE2 2.64Å; E41-H63 PolarHBondContact OE2-NE2 3.32Å; I61-H63 WeakPolarHBondContact CG2-NE2 3.48Å
64L84.8Confident87.1Confident50 Ų5045.7 Ų45.726%0.26224%0.239SC..  trans-116.629.8-166.4-57.7-179000114.4K67 V68 L81 F83L64-K67 HydrophobicContact CD2-CD 4.47Å; L64-K67 PolarHBondContact O-N 2.88Å; L64-V68 HydrophobicContact CB-CG1 3.87Å; L64-V68 HydrophobicContact CD1-CG1 4.49Å; L64-V68 WeakPolarHBondContact O-CG1 3.24Å; L64-V68 PolarHBondContact O-N 3.34Å; L64-L81 PolarHBondContact N-O 3.1Å; L64-L81 VanDerWaalsContact N-O 3.14Å; L64-F83 HydrophobicContact CD1-CD2 3.78Å; L64-F83 HydrophobicContact CD1-CE2 4.03Å; L64-F83 HydrophobicContact CG-CD2 4.33Å
65N81.4Confident86Confident97 Ų9741.7 Ų41.752%0.51922%0.223SC..THydrogen-bonded Turntrans-52.1-64.8-169.1-166.223.9000113.8E38 R73E38-N65 HydrophobicContact CG-CB 4.3Å; E38-N65 PolarHBondContact OE2-N 2.85Å; N65-R73 PolarHBondContact O-NE 3.2Å
66S80.4Confident85Confident41 Ų4141.7 Ų41.729%0.28722%0.221SC..THydrogen-bonded Turntrans-89.9-1.6179.173.60000113.8E38 R73E38-S66 WeakPolarHBondContact OE1-CB 3.4Å; E38-S66 PolarHBondContact OE1-N 2.99Å; E38-S66 PolarHBondContact OE1-OG 3.43Å; E38-S66 PolarHBondContact OE2-N 2.64Å; E38-S66 PolarHBondContact OE2-OG 3.32Å; S66-R73 VanDerWaalsContact C-NH2 3.27Å; S66-R73 PolarHBondContact O-NH2 3.35Å
67K81.7Confident84.1Confident17 Ų1743.3 Ų43.37%0.07423%0.233CC..THydrogen-bonded Turntrans-88.3-17.5-180-70.8-175.7171.3-157.90115.2E33 E38 L64 R264 A268E33-K67 PolarHBondContact O-NZ 3.37Å; E33-K67 IonicContact OE2-NZ 3.37Å; E33-K67 PolarHBondContact OE2-NZ 2.92Å; E38-K67 WeakPolarHBondContact OE2-CG 3.38Å; E38-K67 PolarHBondContact OE2-N 2.7Å; L64-K67 HydrophobicContact CD2-CD 4.47Å; L64-K67 PolarHBondContact O-N 2.88Å; K67-R264 WeakPolarHBondContact CE-O 3.15Å; K67-R264 PolarHBondContact NZ-O 3.14Å; K67-A268 PolarHBondContact O-N 3.32Å
68V80.4Confident83Confident17 Ų1751.4 Ų51.410%0.10327%0.272CS..SBendtrans-87156.7177.3-61.60000112.7L64 V72 R73 L81L64-V68 HydrophobicContact CB-CG1 3.87Å; L64-V68 HydrophobicContact CD1-CG1 4.49Å; L64-V68 WeakPolarHBondContact O-CG1 3.24Å; L64-V68 PolarHBondContact O-N 3.34Å; V68-V72 HydrophobicContact CB-CB 4.24Å; V68-V72 HydrophobicContact CB-CG1 4.21Å; V68-V72 HydrophobicContact CG2-CB 4.2Å; V68-V72 HydrophobicContact CG2-CG1 4.13Å; V68-R73 HydrophobicContact CG2-CG 3.56Å; V68-R73 PolarHBondContact O-NE 3.08Å; V68-R73 PolarHBondContact O-NH2 2.86Å; V68-L81 HydrophobicContact CG2-CD1 3.49Å; V68-L81 VanDerWaalsContact CG2-CD1 3.49Å; V68-L81 HydrophobicContact CG2-CD2 4.02Å; V68-L81 HydrophobicContact CG2-CG 4.35Å
69P78.6Confident81.8Confident1 Ų153 Ų531%0.00629%0.293CS..  trans-57.3151.4175.9-23.831.8000113.8F71 V72 R73 F212 A268P69-F71 VanDerWaalsContact C-N 3.26Å; P69-F71 HydrophobicContact CB-CD1 3.51Å; P69-F71 HydrophobicContact CB-CE1 3.31Å; P69-F71 HydrophobicContact CB-CG 4.43Å; P69-F71 HydrophobicContact CB-CZ 4.11Å; P69-F71 HydrophobicContact CG-CD1 4.4Å; P69-F71 HydrophobicContact CG-CE1 3.72Å; P69-F71 HydrophobicContact CG-CZ 4.18Å; P69-F71 PolarHBondContact O-N 2.71Å; P69-V72 HydrophobicContact CB-CG2 4.26Å; P69-V72 HydrophobicContact CG-CG2 4.24Å; P69-V72 WeakPolarHBondContact O-CB 3.19Å; P69-V72 PolarHBondContact O-N 2.9Å; P69-R73 PolarHBondContact O-N 3.36Å; P69-F212 HydrophobicContact CG-CE1 3.76Å; P69-F212 HydrophobicContact CG-CE2 3.6Å; P69-F212 HydrophobicContact CG-CZ 3.15Å; P69-A268 WeakPolarHBondContact CA-O 3.17Å; P69-A268 HydrophobicContact CG-CB 4.15Å; P69-A268 WeakPolarHBondContact CG-O 3.38Å
70G77.5Confident81Confident42 Ų4252.7 Ų52.743%0.43329%0.293SS..Hα-helixtrans-56.8-3618000000114V72 R73 L74G70-V72 VanDerWaalsContact C-N 3.28Å; G70-V72 PolarHBondContact O-N 3.12Å; G70-R73 PolarHBondContact O-N 3.24Å; G70-L74 PolarHBondContact O-N 2.85Å
71F76.6Confident80.4Confident51 Ų5152.3 Ų52.322%0.22429%0.292CS..Hα-helixtrans-67.5-28177.575.9-95.6000113P69 V209 F212P69-F71 VanDerWaalsContact C-N 3.26Å; P69-F71 HydrophobicContact CB-CD1 3.51Å; P69-F71 HydrophobicContact CB-CE1 3.31Å; P69-F71 HydrophobicContact CB-CG 4.43Å; P69-F71 HydrophobicContact CB-CZ 4.11Å; P69-F71 HydrophobicContact CG-CD1 4.4Å; P69-F71 HydrophobicContact CG-CE1 3.72Å; P69-F71 HydrophobicContact CG-CZ 4.18Å; P69-F71 PolarHBondContact O-N 2.71Å; F71-V209 HydrophobicContact CE2-CG2 4.13Å; F71-F212 HydrophobicContact CZ-CD1 4.34Å; F71-F212 HydrophobicContact CZ-CD2 4.46Å; F71-F212 HydrophobicContact CZ-CG 4.2Å
72V78.1Confident80.2Confident25 Ų2553.3 Ų53.315%0.15230%0.299CS..Hα-helixtrans-74.2-40.1174.4179.70000109.8V68 P69 G70 L74 I75 A76 L81V68-V72 HydrophobicContact CB-CB 4.24Å; V68-V72 HydrophobicContact CB-CG1 4.21Å; V68-V72 HydrophobicContact CG2-CB 4.2Å; V68-V72 HydrophobicContact CG2-CG1 4.13Å; P69-V72 HydrophobicContact CB-CG2 4.26Å; P69-V72 HydrophobicContact CG-CG2 4.24Å; P69-V72 WeakPolarHBondContact O-CB 3.19Å; P69-V72 PolarHBondContact O-N 2.9Å; G70-V72 VanDerWaalsContact C-N 3.28Å; G70-V72 PolarHBondContact O-N 3.12Å; V72-L74 VanDerWaalsContact C-N 3.34Å; V72-L74 PolarHBondContact O-N 3.01Å; V72-I75 VanDerWaalsContact O-CG1 3.24Å; V72-I75 WeakPolarHBondContact O-CG1 3.39Å; V72-I75 PolarHBondContact O-N 3.13Å; V72-A76 VanDerWaalsContact O-CB 3.22Å; V72-A76 WeakPolarHBondContact O-CB 3.33Å; V72-A76 PolarHBondContact O-N 3.17Å; V72-L81 HydrophobicContact CG1-CD2 3.93Å
73R78.8Confident80.2Confident89 Ų8952.1 Ų52.134%0.33630%0.295SS..Hα-helixtrans-64.6-37.4176.2-57.2-171.7-146.5172.66.9112.5N65 S66 V68 P69 G70 I75 A76 L81N65-R73 PolarHBondContact O-NE 3.2Å; S66-R73 VanDerWaalsContact C-NH2 3.27Å; S66-R73 PolarHBondContact O-NH2 3.35Å; V68-R73 HydrophobicContact CG2-CG 3.56Å; V68-R73 PolarHBondContact O-NE 3.08Å; V68-R73 PolarHBondContact O-NH2 2.86Å; P69-R73 PolarHBondContact O-N 3.36Å; G70-R73 PolarHBondContact O-N 3.24Å; R73-I75 PolarHBondContact O-N 3.43Å; R73-A76 PolarHBondContact O-N 3.41Å; R73-A76 VanDerWaalsContact O-O 3.1Å; R73-L81 HydrophobicContact CG-CD1 4.05Å
74L75.7Confident80.4Confident156 Ų15651.9 Ų51.982%0.81729%0.294SS*.Hα-helixtrans-62.3-28.9-178.2-171.166.7000113.2G70 V72G70-L74 PolarHBondContact O-N 2.85Å; V72-L74 VanDerWaalsContact C-N 3.34Å; V72-L74 PolarHBondContact O-N 3.01Å
75I72.7Confident81.1Confident45 Ų4550.6 Ų50.623%0.23129%0.287CS..Hα-helixtrans-101-12.2-17865.8176.7000113.1V72 R73 F200 W202 L205V72-I75 VanDerWaalsContact O-CG1 3.24Å; V72-I75 WeakPolarHBondContact O-CG1 3.39Å; V72-I75 PolarHBondContact O-N 3.13Å; R73-I75 PolarHBondContact O-N 3.43Å; I75-F200 HydrophobicContact CD1-CZ 4.36Å; I75-W202 HydrophobicContact CB-CH2 4.22Å; I75-W202 HydrophobicContact CB-CZ2 4.14Å; I75-W202 VanDerWaalsContact O-CH2 3.3Å; I75-W202 WeakPolarHBondContact O-CH2 3.4Å; I75-L205 HydrophobicContact CD1-CD1 3.59Å; I75-L205 HydrophobicContact CG2-CD1 4.06Å
76A75.4Confident81.9Confident22 Ų2249.7 Ų49.718%0.18228%0.278CS..SBendtrans-95.4121.2-178.400000109.8V72 R73 S80 L81V72-A76 VanDerWaalsContact O-CB 3.22Å; V72-A76 WeakPolarHBondContact O-CB 3.33Å; V72-A76 PolarHBondContact O-N 3.17Å; R73-A76 PolarHBondContact O-N 3.41Å; R73-A76 VanDerWaalsContact O-O 3.1Å; A76-S80 WeakPolarHBondContact CB-OG 3.23Å; A76-L81 HydrophobicContact CB-CD1 4.45Å; A76-L81 HydrophobicContact CB-CD2 3.66Å; A76-L81 HydrophobicContact CB-CG 3.93Å
77P77.7Confident82.7Confident58 Ų5848.1 Ų48.138%0.37727%0.268SS..PPolyproline II helixtrans-54.7154.1169.8-25.234000112.2G79 S80 Y102P77-G79 PolarHBondContact O-N 3.31Å; P77-S80 WeakPolarHBondContact CD-OG 3.2Å; P77-S80 VanDerWaalsContact O-CB 3.26Å; P77-S80 WeakPolarHBondContact O-CB 3.26Å; P77-S80 PolarHBondContact O-N 3.21Å; P77-S80 PolarHBondContact O-OG 3.25Å; P77-Y102 HydrophobicContact CG-CD2 4.19Å; P77-Y102 HydrophobicContact CG-CE1 4.07Å; P77-Y102 HydrophobicContact CG-CE2 3.63Å
78E73.7Confident83.5Confident202 Ų20250.7 Ų50.794%0.94428%0.277SS*.THydrogen-bonded Turntrans-55132.3176.1-169.3175.1-176.200110.8S80E78-S80 VanDerWaalsContact C-N 3.26Å; E78-S80 PolarHBondContact O-N 2.9Å
79G71.5Confident84.3Confident55 Ų5551.2 Ų51.257%0.56728%0.279SS*.THydrogen-bonded Turntrans77.8-2.9-176.200000115.5P77 L81 V82P77-G79 PolarHBondContact O-N 3.31Å; G79-L81 VanDerWaalsContact C-N 3.31Å; G79-L81 PolarHBondContact O-N 3.38Å; G79-V82 WeakPolarHBondContact O-CG2 3.4Å
80S80.2Confident85.2Confident17 Ų1751.9 Ų51.912%0.11929%0.285CS..  trans-84-1.5-179.687.70000114.3A76 P77 E78 V82 N100A76-S80 WeakPolarHBondContact CB-OG 3.23Å; P77-S80 WeakPolarHBondContact CD-OG 3.2Å; P77-S80 VanDerWaalsContact O-CB 3.26Å; P77-S80 WeakPolarHBondContact O-CB 3.26Å; P77-S80 PolarHBondContact O-N 3.21Å; P77-S80 PolarHBondContact O-OG 3.25Å; E78-S80 VanDerWaalsContact C-N 3.26Å; E78-S80 PolarHBondContact O-N 2.9Å; S80-V82 PolarHBondContact O-N 3.31Å; S80-N100 PolarHBondContact O-ND2 2.61Å
81L84.3Confident86.1Confident14 Ų1451.8 Ų51.87%0.07327%0.272CS..  trans-89.539.6179-64.7171.8000112.3L64 V68 V72 R73 A76 G79 F83L64-L81 PolarHBondContact N-O 3.1Å; L64-L81 VanDerWaalsContact N-O 3.14Å; V68-L81 HydrophobicContact CG2-CD1 3.49Å; V68-L81 VanDerWaalsContact CG2-CD1 3.49Å; V68-L81 HydrophobicContact CG2-CD2 4.02Å; V68-L81 HydrophobicContact CG2-CG 4.35Å; V72-L81 HydrophobicContact CG1-CD2 3.93Å; R73-L81 HydrophobicContact CG-CD1 4.05Å; A76-L81 HydrophobicContact CB-CD1 4.45Å; A76-L81 HydrophobicContact CB-CD2 3.66Å; A76-L81 HydrophobicContact CB-CG 3.93Å; G79-L81 VanDerWaalsContact C-N 3.31Å; G79-L81 PolarHBondContact O-N 3.38Å; L81-F83 HydrophobicContact CD2-CE2 4.42Å
82V90Very high87.1Confident41 Ų4151.8 Ų51.825%0.24828%0.277CS..EExtended strand (participates in β ladder)trans-110.2122.8176.6-179.30000107.4I61 Y62 G79 S80 N100I61-V82 HydrophobicContact CG2-CG1 3.33Å; Y62-V82 WeakPolarHBondContact O-CA 3.47Å; G79-V82 WeakPolarHBondContact O-CG2 3.4Å; S80-V82 PolarHBondContact O-N 3.31Å; V82-N100 PolarHBondContact O-ND2 3.22Å
83F93.4Very high88Confident22 Ų2251.6 Ų51.610%0.09627%0.274CS..EExtended strand (participates in β ladder)trans-118.4133.6-176.9-62.6-95.5000110.3I61 Y62 L64 L81 V98 T99 N100 M103 F107I61-F83 CarbonylContact C-O 3.57Å; I61-F83 WeakPolarHBondContact CA-O 3.37Å; Y62-F83 HydrophobicContact CD2-CB 4.49Å; Y62-F83 PolarHBondContact N-O 3.46Å; Y62-F83 PolarHBondContact O-N 2.87Å; L64-F83 HydrophobicContact CD1-CD2 3.78Å; L64-F83 HydrophobicContact CD1-CE2 4.03Å; L64-F83 HydrophobicContact CG-CD2 4.33Å; L81-F83 HydrophobicContact CD2-CE2 4.42Å; F83-V98 HydrophobicContact CB-CG1 3.82Å; F83-V98 HydrophobicContact CD1-CG1 4.3Å; F83-V98 HydrophobicContact CG-CG1 4.47Å; F83-T99 CarbonylContact C-O 3.54Å; F83-T99 WeakPolarHBondContact CA-O 3.14Å; F83-N100 HydrophobicContact CD1-CB 3.9Å; F83-N100 HydrophobicContact CE1-CB 3.92Å; F83-M103 HydrophobicContact CE1-CE 3.98Å; F83-M103 HydrophobicContact CZ-CE 4.48Å; F83-F107 HydrophobicContact CD1-CD1 4.42Å; F83-F107 AromaticContact CD1-CE1 3.53Å; F83-F107 HydrophobicContact CD1-CE1 3.53Å; F83-F107 AromaticContact CD1-CZ 3.81Å; F83-F107 HydrophobicContact CD1-CZ 3.81Å; F83-F107 HydrophobicContact CE1-CD1 4.31Å; F83-F107 AromaticContact CE1-CE1 3.58Å; F83-F107 HydrophobicContact CE1-CE1 3.58Å; F83-F107 HydrophobicContact CE1-CE2 4.33Å; F83-F107 AromaticContact CE1-CZ 3.56Å; F83-F107 HydrophobicContact CE1-CZ 3.56Å
84H96.4Very high88.9Confident27 Ų2747.9 Ų47.913%0.12526%0.261CS..EExtended strand (participates in β ladder)trans-98.2114.4178.8-71.8-125.1000108.3H59 V98 T99 E101H59-H84 AromaticContact CE1-ND1 3.75Å; H59-H84 AromaticContact NE2-CG 3.88Å; H59-H84 AromaticContact NE2-ND1 3.15Å; H59-H84 PolarHBondContact NE2-ND1 3.16Å; H59-H84 VanDerWaalsContact NE2-ND1 3.15Å; H84-V98 CarbonylContact O-C 3.51Å; H84-V98 VanDerWaalsContact O-CA 3.28Å; H84-V98 WeakPolarHBondContact O-CA 3.34Å; H84-T99 PolarHBondContact N-O 3.06Å; H84-T99 PolarHBondContact O-N 2.71Å; H84-E101 IonicContact CE1-OE1 3.36Å; H84-E101 IonicContact NE2-OE1 3.26Å
85E97.8Very high90Very high24 Ų2444.9 Ų44.911%0.11224%0.239CC..EExtended strand (participates in β ladder)trans-92.9126.1168.6-178.9-175.891.800109.5H59 K60 Y62 T96 V98H59-E85 CarbonylContact C-O 3.58Å; H59-E85 VanDerWaalsContact CA-O 3.32Å; H59-E85 WeakPolarHBondContact CA-O 3.5Å; H59-E85 PolarHBondContact CD2-O 3.47Å; K60-E85 HydrophobicContact CB-CB 4.34Å; K60-E85 PolarHBondContact N-O 2.87Å; K60-E85 PolarHBondContact O-N 3.41Å; Y62-E85 HydrophobicContact CD2-CB 4.46Å; Y62-E85 HydrophobicContact CE2-CB 3.79Å; Y62-E85 HydrophobicContact CE2-CG 4.39Å; Y62-E85 PolarHBondContact OH-OE1 2.57Å; Y62-E85 PolarHBondContact OH-OE2 3.21Å; E85-T96 HydrophobicContact CG-CG2 3.41Å; E85-T96 VanDerWaalsContact CG-CG2 3.41Å; E85-V98 HydrophobicContact CB-CG2 4.29Å; E85-V98 HydrophobicContact CG-CG2 4.26Å
86K98.2Very high91.2Very high78 Ų7843.6 Ų43.634%0.33923%0.233SC..EExtended strand (participates in β ladder)trans-119.6125.4166.9-65.8179.1-179.6174.70108.8Y57 T58 H59 W88 T96 I97Y57-K86 HydrophobicContact CE2-CB 4.14Å; Y57-K86 HydrophobicContact CE2-CG 4.48Å; Y57-K86 WeakPolarHBondContact OH-CD 3.45Å; Y57-K86 WeakPolarHBondContact OH-CG 3.4Å; T58-K86 WeakPolarHBondContact O-CA 3.42Å; H59-K86 HydrophobicContact CB-CG 4.48Å; K86-W88 HydrophobicContact CB-CH2 3.71Å; K86-W88 HydrophobicContact CB-CZ3 3.78Å; K86-W88 HydrophobicContact CD-CH2 4.34Å; K86-T96 CarbonylContact O-C 3.6Å; K86-T96 WeakPolarHBondContact O-CA 3.19Å; K86-I97 PolarHBondContact N-O 2.94Å; K86-I97 PolarHBondContact O-N 3.26Å
87A97.9Very high92.3Very high8 Ų844.9 Ų44.97%0.06624%0.236CC..EExtended strand (participates in β ladder)trans-124.6139.9179.700000111.4Y57 T58 R95 T96Y57-A87 WeakPolarHBondContact CA-O 3.39Å; Y57-A87 WeakPolarHBondContact CD2-O 3.27Å; T58-A87 PolarHBondContact N-O 2.81Å; T58-A87 PolarHBondContact O-N 3.5Å; A87-R95 CarbonylContact C-O 3.57Å; A87-R95 VanDerWaalsContact CA-O 3.31Å; A87-R95 WeakPolarHBondContact CA-O 3.33Å; A87-T96 HydrophobicContact CB-CG2 4.17Å; A87-T96 WeakPolarHBondContact CB-OG1 3.43Å
88W98.1Very high93.2Very high71 Ų7142.6 Ų42.627%0.26922%0.221SC..EExtended strand (participates in β ladder)trans-11898.2174-68.3-91.5000107.3Y48 Y57 K86 C94 R95 I97Y48-W88 HydrophobicContact CE1-CB 4.15Å; Y48-W88 AromaticContact CE2-CD1 3.87Å; Y48-W88 AromaticContact CZ-CD1 3.8Å; Y57-W88 AromaticContact CD2-CD1 3.85Å; Y57-W88 HydrophobicContact CD2-CD2 4.16Å; Y57-W88 AromaticContact CD2-CE2 3.7Å; Y57-W88 HydrophobicContact CD2-CG 4.26Å; Y57-W88 HydrophobicContact CD2-CZ2 4.18Å; Y57-W88 AromaticContact CD2-NE1 3.47Å; Y57-W88 HydrophobicContact CE2-CD2 4.35Å; Y57-W88 AromaticContact CE2-CE2 3.69Å; Y57-W88 HydrophobicContact CE2-CH2 4.29Å; Y57-W88 AromaticContact CE2-CZ2 3.67Å; Y57-W88 HydrophobicContact CE2-CZ2 3.67Å; Y57-W88 AromaticContact CE2-NE1 3.87Å; K86-W88 HydrophobicContact CB-CH2 3.71Å; K86-W88 HydrophobicContact CB-CZ3 3.78Å; K86-W88 HydrophobicContact CD-CH2 4.34Å; W88-C94 WeakPolarHBondContact O-CA 3.13Å; W88-R95 PolarHBondContact N-O 3.45Å; W88-R95 PolarHBondContact O-N 2.97Å; W88-I97 HydrophobicContact CH2-CD1 4.49Å; W88-I97 HydrophobicContact CZ3-CB 4.45Å; W88-I97 HydrophobicContact CZ3-CD1 3.92Å; W88-I97 HydrophobicContact CZ3-CG1 4.11Å
89N97.1Very high94.3Very high27 Ų2735.4 Ų35.414%0.14419%0.191CC..EExtended strand (participates in β ladder)trans-9893-177.2-173.8-3.1000110G55 Q56 Y91G55-N89 CarbonylContact C-O 3.58Å; G55-N89 WeakPolarHBondContact CA-O 3.29Å; Q56-N89 HydrophobicContact CB-CB 4.49Å; Q56-N89 PolarHBondContact N-O 2.72Å; Q56-N89 PolarHBondContact O-N 3.29Å; N89-Y91 PolarHBondContact OD1-N 2.78Å
90A97.1Very high95.3Very high16 Ų1633 Ų3313%0.13217%0.165CC..EExtended strand (participates in β ladder)trans-104.258.4172.600000109.6E53 K54 Y93E53-A90 HydrophobicContact CG-CB 3.54Å; K54-A90 WeakPolarHBondContact O-CB 3.32Å; A90-Y93 CarbonylContact C-O 3.56Å; A90-Y93 WeakPolarHBondContact CA-O 3.2Å; A90-Y93 PolarHBondContact N-O 2.67Å; A90-Y93 PolarHBondContact O-N 2.94Å
91Y97Very high95.8Very high40 Ų4039 Ų3916%0.15719%0.192CC..THydrogen-bonded Turntrans-44.5129.2-173-164.5-93.3000111.7I15 Y18 Q19 N89 Y93 H115I15-Y91 WeakPolarHBondContact CA-OH 3.43Å; I15-Y91 HydrophobicContact CB-CE1 4.43Å; I15-Y91 VanDerWaalsContact O-CE1 3.23Å; I15-Y91 WeakPolarHBondContact O-CE1 3.36Å; I15-Y91 PolarHBondContact O-OH 3.31Å; Y18-Y91 HydrophobicContact CD1-CE2 4.03Å; Q19-Y91 HydrophobicContact CB-CD1 3.95Å; Q19-Y91 HydrophobicContact CB-CD2 4.41Å; Q19-Y91 HydrophobicContact CB-CE1 3.81Å; Q19-Y91 HydrophobicContact CB-CE2 4.29Å; Q19-Y91 HydrophobicContact CB-CG 4.25Å; Q19-Y91 HydrophobicContact CG-CD1 3.88Å; Q19-Y91 HydrophobicContact CG-CD2 4.23Å; Q19-Y91 HydrophobicContact CG-CE1 4.27Å; Q19-Y91 HydrophobicContact CG-CG 3.86Å; N89-Y91 PolarHBondContact OD1-N 2.78Å; Y91-Y93 PolarHBondContact N-O 3.22Å; Y91-H115 AromaticContact CD2-ND1 3.75Å; Y91-H115 HydrophobicContact CE2-CB 3.94Å; Y91-H115 AromaticContact CE2-CE1 3.73Å; Y91-H115 AromaticContact CE2-CG 3.46Å; Y91-H115 VanDerWaalsContact CE2-CG 3.46Å; Y91-H115 AromaticContact CE2-ND1 3.27Å; Y91-H115 VanDerWaalsContact CE2-ND1 3.27Å; Y91-H115 WeakPolarHBondContact CE2-ND1 3.25Å; Y91-H115 AromaticContact CZ-CG 3.91Å; Y91-H115 WeakPolarHBondContact OH-CB 3.41Å
92P97.6Very high96.1Very high50 Ų5044 Ų4433%0.32521%0.21SC..THydrogen-bonded Turncis-88.46.418.735.1-36.9000116.1W114 H115P92-W114 HydrophobicContact CG-CZ3 4.16Å; P92-H115 HydrophobicContact CB-CB 4.19Å; P92-H115 PolarHBondContact O-N 3.23Å; P92-H115 PolarHBondContact O-ND1 3.25Å
93Y98.1Very high96.1Very high22 Ų2243.4 Ų43.49%0.08621%0.205CC..EExtended strand (participates in β ladder)trans-101.8140.8172.1178.4-106000111.1A90 Y91 R95 E112 T113 W114A90-Y93 CarbonylContact C-O 3.56Å; A90-Y93 WeakPolarHBondContact CA-O 3.2Å; A90-Y93 PolarHBondContact N-O 2.67Å; A90-Y93 PolarHBondContact O-N 2.94Å; Y91-Y93 PolarHBondContact N-O 3.22Å; Y93-R95 HydrophobicContact CE1-CB 4.02Å; Y93-R95 VanDerWaalsContact OH-CZ 3.31Å; Y93-R95 PolarHBondContact OH-NE 3.17Å; Y93-R95 VanDerWaalsContact OH-NE 3.14Å; Y93-R95 PolarHBondContact OH-NH2 3.18Å; Y93-E112 HydrophobicContact CE2-CB 4.28Å; Y93-E112 PolarHBondContact OH-OE1 3.14Å; Y93-T113 WeakPolarHBondContact CA-O 3.12Å; Y93-T113 VanDerWaalsContact CD2-O 3.28Å; Y93-T113 WeakPolarHBondContact CD2-O 3.49Å; Y93-W114 AromaticContact CD2-CD1 3.98Å; Y93-W114 AromaticContact CD2-CD2 3.93Å; Y93-W114 HydrophobicContact CD2-CD2 3.93Å; Y93-W114 AromaticContact CD2-CE2 3.58Å; Y93-W114 HydrophobicContact CD2-CG 4.18Å; Y93-W114 AromaticContact CD2-CZ2 3.97Å; Y93-W114 HydrophobicContact CD2-CZ2 3.97Å; Y93-W114 AromaticContact CD2-NE1 3.61Å; Y93-W114 AromaticContact CE2-NE1 3.94Å; Y93-W114 HydrophobicContact CG-CZ2 4.21Å
94C97.7Very high95.9Very high10 Ų1049.9 Ų49.97%0.06823%0.233CC..EExtended strand (participates in β ladder)trans-138.6138.6173.4-177.20000110.1W88 E112 T113W88-C94 WeakPolarHBondContact O-CA 3.13Å; C94-E112 WeakPolarHBondContact O-CA 3.38Å; C94-T113 PolarHBondContact N-O 3.27Å; C94-T113 PolarHBondContact O-N 3.42Å
95R98.2Very high95.7Very high93 Ų9355.1 Ų55.135%0.35126%0.262SS..EExtended strand (participates in β ladder)trans-122.7122.8172.8179.3-179.2-67.8140.7-1109.6A87 W88 Y93 I97 E112A87-R95 CarbonylContact C-O 3.57Å; A87-R95 VanDerWaalsContact CA-O 3.31Å; A87-R95 WeakPolarHBondContact CA-O 3.33Å; W88-R95 PolarHBondContact N-O 3.45Å; W88-R95 PolarHBondContact O-N 2.97Å; Y93-R95 HydrophobicContact CE1-CB 4.02Å; Y93-R95 VanDerWaalsContact OH-CZ 3.31Å; Y93-R95 PolarHBondContact OH-NE 3.17Å; Y93-R95 VanDerWaalsContact OH-NE 3.14Å; Y93-R95 PolarHBondContact OH-NH2 3.18Å; R95-I97 HydrophobicContact CG-CG1 4.4Å; R95-E112 HydrophobicContact CG-CG 4.17Å; R95-E112 IonicContact CZ-OE1 3.87Å; R95-E112 IonicContact NE-OE1 2.71Å; R95-E112 PolarHBondContact NE-OE1 2.86Å; R95-E112 IonicContact NH2-OE1 3.21Å; R95-E112 PolarHBondContact NH2-OE1 3.42Å
96T98.2Very high95.5Very high18 Ų1856.2 Ų56.211%0.1127%0.273CS..EExtended strand (participates in β ladder)trans-117.6136.8174.6-57.50000109.8E85 K86 A87 V98 K110 I111E85-T96 HydrophobicContact CG-CG2 3.41Å; E85-T96 VanDerWaalsContact CG-CG2 3.41Å; K86-T96 CarbonylContact O-C 3.6Å; K86-T96 WeakPolarHBondContact O-CA 3.19Å; A87-T96 HydrophobicContact CB-CG2 4.17Å; A87-T96 WeakPolarHBondContact CB-OG1 3.43Å; T96-V98 HydrophobicContact CG2-CG2 4.44Å; T96-K110 CarbonylContact O-C 3.28Å; T96-K110 WeakPolarHBondContact O-CA 3.33Å; T96-I111 PolarHBondContact N-O 3.33Å; T96-I111 PolarHBondContact O-N 3.35Å
97I98.2Very high95.3Very high50 Ų5053 Ų5326%0.25626%0.258SS..EExtended strand (participates in β ladder)trans-128.3120.8176.1-53.9178.7000108.1K86 W88 R95 T99 I109 K110K86-I97 PolarHBondContact N-O 2.94Å; K86-I97 PolarHBondContact O-N 3.26Å; W88-I97 HydrophobicContact CH2-CD1 4.49Å; W88-I97 HydrophobicContact CZ3-CB 4.45Å; W88-I97 HydrophobicContact CZ3-CD1 3.92Å; W88-I97 HydrophobicContact CZ3-CG1 4.11Å; R95-I97 HydrophobicContact CG-CG1 4.4Å; I97-T99 HydrophobicContact CG2-CG2 3.96Å; I97-I109 CarbonylContact C-O 3.57Å; I97-I109 WeakPolarHBondContact CA-O 3.35Å; I97-K110 HydrophobicContact CG1-CG 4.32Å
98V97.4Very high95.2Very high9 Ų954.8 Ų54.86%0.05527%0.265CS..EExtended strand (participates in β ladder)trans-105126.8173.4-172.10000108.8F83 H84 E85 T96 F107 F108 I109F83-V98 HydrophobicContact CB-CG1 3.82Å; F83-V98 HydrophobicContact CD1-CG1 4.3Å; F83-V98 HydrophobicContact CG-CG1 4.47Å; H84-V98 CarbonylContact O-C 3.51Å; H84-V98 VanDerWaalsContact O-CA 3.28Å; H84-V98 WeakPolarHBondContact O-CA 3.34Å; E85-V98 HydrophobicContact CB-CG2 4.29Å; E85-V98 HydrophobicContact CG-CG2 4.26Å; T96-V98 HydrophobicContact CG2-CG2 4.44Å; V98-F107 HydrophobicContact CG1-CE1 4.49Å; V98-F108 VanDerWaalsContact O-CA 3.27Å; V98-F108 WeakPolarHBondContact O-CA 3.28Å; V98-I109 HydrophobicContact CB-CB 4.11Å; V98-I109 HydrophobicContact CG2-CB 4.49Å; V98-I109 PolarHBondContact N-O 2.86Å; V98-I109 PolarHBondContact O-N 3.32Å
99T96.2Very high95.2Very high52 Ų5252.1 Ų52.132%0.31926%0.256SS..EExtended strand (participates in β ladder)trans-129.116418056.40000111.1F83 H84 I97F83-T99 CarbonylContact C-O 3.54Å; F83-T99 WeakPolarHBondContact CA-O 3.14Å; H84-T99 PolarHBondContact N-O 3.06Å; H84-T99 PolarHBondContact O-N 2.71Å; I97-T99 HydrophobicContact CG2-CG2 3.96Å
100N93.2Very high95.2Very high4 Ų453.5 Ų53.52%0.02126%0.261CS..EExtended strand (participates in β ladder)trans-132.3127.7177.1175.5-96.8000109.1S80 V82 F83 Y102 M103 K104 F107S80-N100 PolarHBondContact O-ND2 2.61Å; V82-N100 PolarHBondContact O-ND2 3.22Å; F83-N100 HydrophobicContact CD1-CB 3.9Å; F83-N100 HydrophobicContact CE1-CB 3.92Å; N100-Y102 VanDerWaalsContact C-N 3.33Å; N100-Y102 PolarHBondContact O-N 3.48Å; N100-Y102 WeakPolarHBondContact OD1-CB 3.44Å; N100-Y102 PolarHBondContact OD1-N 3.36Å; N100-M103 HydrophobicContact CB-CB 4.31Å; N100-M103 HydrophobicContact CB-CE 3.55Å; N100-M103 PolarHBondContact O-N 3.08Å; N100-M103 WeakPolarHBondContact OD1-CG 3.37Å; N100-M103 PolarHBondContact OD1-N 3.11Å; N100-K104 PolarHBondContact O-N 3.07Å; N100-F107 HydrophobicContact CB-CD1 3.62Å; N100-F107 HydrophobicContact CB-CE1 4.07Å; N100-F107 HydrophobicContact CB-CG 4.41Å
101E90.8Very high95.3Very high143 Ų14353.6 Ų53.667%0.66826%0.259SS*.THydrogen-bonded Turntrans-64.4-37.6-172.8-63.1-165.8157.700112.8H84 K104H84-E101 IonicContact CE1-OE1 3.36Å; H84-E101 IonicContact NE2-OE1 3.26Å; E101-K104 WeakPolarHBondContact O-CG 3.39Å
102Y89.4Confident95.4Very high120 Ų12052.9 Ų52.947%0.47126%0.257SS..THydrogen-bonded Turntrans-66-45.6179172.6-107.2000111.9P77 N100 W202P77-Y102 HydrophobicContact CG-CD2 4.19Å; P77-Y102 HydrophobicContact CG-CE1 4.07Å; P77-Y102 HydrophobicContact CG-CE2 3.63Å; N100-Y102 VanDerWaalsContact C-N 3.33Å; N100-Y102 PolarHBondContact O-N 3.48Å; N100-Y102 WeakPolarHBondContact OD1-CB 3.44Å; N100-Y102 PolarHBondContact OD1-N 3.36Å; Y102-W202 HydrophobicContact CE1-CH2 4.03Å; Y102-W202 HydrophobicContact CE1-CZ3 4.11Å
103M89.3Confident95.5Very high27 Ų2750.8 Ų50.813%0.13324%0.243CC..THydrogen-bonded Turntrans-78.6-16.6-177.8-67.7-172.3-7800114F83 N100 D105 S106 F107 F200F83-M103 HydrophobicContact CE1-CE 3.98Å; F83-M103 HydrophobicContact CZ-CE 4.48Å; N100-M103 HydrophobicContact CB-CB 4.31Å; N100-M103 HydrophobicContact CB-CE 3.55Å; N100-M103 PolarHBondContact O-N 3.08Å; N100-M103 WeakPolarHBondContact OD1-CG 3.37Å; N100-M103 PolarHBondContact OD1-N 3.11Å; M103-D105 PolarHBondContact O-N 2.68Å; M103-S106 WeakPolarHBondContact O-CB 3.35Å; M103-S106 PolarHBondContact O-N 2.87Å; M103-F107 HydrophobicContact CB-CB 3.53Å; M103-F107 HydrophobicContact CE-CB 3.61Å; M103-F107 HydrophobicContact CE-CD1 3.78Å; M103-F107 HydrophobicContact CE-CD2 3.72Å; M103-F107 HydrophobicContact CE-CE1 4.36Å; M103-F107 HydrophobicContact CE-CE2 4.25Å; M103-F107 HydrophobicContact CE-CG 3.4Å; M103-F107 HydrophobicContact CG-CB 4.22Å; M103-F107 HydrophobicContact SD-CB 3.69Å; M103-F107 HydrophobicContact SD-CD2 4.33Å; M103-F107 HydrophobicContact SD-CG 4.09Å; M103-F200 HydrophobicContact CE-CE2 4.49Å; M103-F200 HydrophobicContact SD-CD2 3.85Å; M103-F200 HydrophobicContact SD-CE2 3.46Å; M103-F200 WeakPolarHBondContact SD-CE2 3.21Å
104K90.8Very high95.5Very high158 Ų15853.1 Ų53.169%0.68725%0.252SS*.G310 helixtrans48.8-133.3-179.2-55.5-179.2-179.4179.40110.9N100 E101 S106 F107N100-K104 PolarHBondContact O-N 3.07Å; E101-K104 WeakPolarHBondContact O-CG 3.39Å; K104-S106 PolarHBondContact O-N 3.33Å; K104-S106 VanDerWaalsContact O-N 3.08Å; K104-F107 PolarHBondContact O-N 2.92Å
105D92.3Very high95.5Very high137 Ų13752.8 Ų52.873%0.73325%0.249SC*.G310 helixtrans-67.1-7.9179.9-58.3-41.4000114.3M103 F107 K199M103-D105 PolarHBondContact O-N 2.68Å; D105-F107 VanDerWaalsContact C-N 3.25Å; D105-K199 WeakPolarHBondContact O-CE 3.31Å; D105-K199 PolarHBondContact O-NZ 3.33Å
106S91.8Very high95.5Very high48 Ų4850.6 Ų50.634%0.33624%0.242SC..G310 helixtrans-77.3-12.6176.5-58.30000112.5M103 K104 F200 K201M103-S106 WeakPolarHBondContact O-CB 3.35Å; M103-S106 PolarHBondContact O-N 2.87Å; K104-S106 PolarHBondContact O-N 3.33Å; K104-S106 VanDerWaalsContact O-N 3.08Å; S106-F200 CarbonylContact O-C 3.59Å; S106-F200 VanDerWaalsContact O-CA 3.32Å; S106-F200 WeakPolarHBondContact O-CA 3.42Å; S106-K201 PolarHBondContact O-N 2.8Å
107F93.9Very high95.5Very high9 Ų954.2 Ų54.24%0.03927%0.266CS..EExtended strand (participates in β ladder)trans-135.3132.4178.1172.8-96000112.9F83 V98 N100 M103 K104 D105 I109 K199 F200 I213F83-F107 HydrophobicContact CD1-CD1 4.42Å; F83-F107 AromaticContact CD1-CE1 3.53Å; F83-F107 HydrophobicContact CD1-CE1 3.53Å; F83-F107 AromaticContact CD1-CZ 3.81Å; F83-F107 HydrophobicContact CD1-CZ 3.81Å; F83-F107 HydrophobicContact CE1-CD1 4.31Å; F83-F107 AromaticContact CE1-CE1 3.58Å; F83-F107 HydrophobicContact CE1-CE1 3.58Å; F83-F107 HydrophobicContact CE1-CE2 4.33Å; F83-F107 AromaticContact CE1-CZ 3.56Å; F83-F107 HydrophobicContact CE1-CZ 3.56Å; V98-F107 HydrophobicContact CG1-CE1 4.49Å; N100-F107 HydrophobicContact CB-CD1 3.62Å; N100-F107 HydrophobicContact CB-CE1 4.07Å; N100-F107 HydrophobicContact CB-CG 4.41Å; M103-F107 HydrophobicContact CB-CB 3.53Å; M103-F107 HydrophobicContact CE-CB 3.61Å; M103-F107 HydrophobicContact CE-CD1 3.78Å; M103-F107 HydrophobicContact CE-CD2 3.72Å; M103-F107 HydrophobicContact CE-CE1 4.36Å; M103-F107 HydrophobicContact CE-CE2 4.25Å; M103-F107 HydrophobicContact CE-CG 3.4Å; M103-F107 HydrophobicContact CG-CB 4.22Å; M103-F107 HydrophobicContact SD-CB 3.69Å; M103-F107 HydrophobicContact SD-CD2 4.33Å; M103-F107 HydrophobicContact SD-CG 4.09Å; K104-F107 PolarHBondContact O-N 2.92Å; D105-F107 VanDerWaalsContact C-N 3.25Å; F107-I109 HydrophobicContact CE2-CD1 4.23Å; F107-I109 HydrophobicContact CE2-CG1 4.01Å; F107-I109 HydrophobicContact CZ-CD1 3.76Å; F107-I109 HydrophobicContact CZ-CG1 3.72Å; F107-K199 VanDerWaalsContact CA-O 3.27Å; F107-K199 WeakPolarHBondContact CA-O 3.24Å; F107-F200 AromaticContact CD2-CD2 3.94Å; F107-F200 HydrophobicContact CD2-CD2 3.94Å; F107-I213 HydrophobicContact CE2-CD1 3.85Å
108F96.4Very high95.4Very high47 Ų4752.9 Ų52.921%0.20626%0.259CS..EExtended strand (participates in β ladder)trans-155155.3154.767-102.4000111L2 V98 K110 T197 K199L2-F108 HydrophobicContact CD2-CE1 4.27Å; L2-F108 HydrophobicContact CD2-CZ 3.74Å; V98-F108 VanDerWaalsContact O-CA 3.27Å; V98-F108 WeakPolarHBondContact O-CA 3.28Å; F108-K110 HydrophobicContact CD2-CB 4Å; F108-K110 HydrophobicContact CE2-CB 4.09Å; F108-T197 HydrophobicContact CE2-CG2 3.78Å; F108-T197 HydrophobicContact CZ-CG2 4.22Å; F108-K199 HydrophobicContact CD1-CB 3.63Å; F108-K199 HydrophobicContact CD1-CD 3.62Å; F108-K199 HydrophobicContact CD1-CG 4.24Å; F108-K199 HydrophobicContact CD2-CB 4.32Å; F108-K199 HydrophobicContact CE1-CB 3.46Å; F108-K199 VanDerWaalsContact CE1-CB 3.46Å; F108-K199 HydrophobicContact CE1-CD 3.26Å; F108-K199 HydrophobicContact CE1-CG 4Å; F108-K199 HydrophobicContact CE2-CB 4.15Å; F108-K199 HydrophobicContact CG-CB 4.07Å; F108-K199 HydrophobicContact CZ-CB 3.72Å; F108-K199 HydrophobicContact CZ-CD 4.16Å; F108-K199 PolarHBondContact N-O 2.99Å; F108-K199 PolarHBondContact O-N 3.3Å
109I97.9Very high95.4Very high14 Ų1454.6 Ų54.67%0.07227%0.267CS..EExtended strand (participates in β ladder)trans-116.1126.6160.9-52.9168.1000106.3I97 V98 F107 I111 V196 T197 V198 I213I97-I109 CarbonylContact C-O 3.57Å; I97-I109 WeakPolarHBondContact CA-O 3.35Å; V98-I109 HydrophobicContact CB-CB 4.11Å; V98-I109 HydrophobicContact CG2-CB 4.49Å; V98-I109 PolarHBondContact N-O 2.86Å; V98-I109 PolarHBondContact O-N 3.32Å; F107-I109 HydrophobicContact CE2-CD1 4.23Å; F107-I109 HydrophobicContact CE2-CG1 4.01Å; F107-I109 HydrophobicContact CZ-CD1 3.76Å; F107-I109 HydrophobicContact CZ-CG1 3.72Å; I109-I111 HydrophobicContact CG2-CG1 4.19Å; I109-V196 HydrophobicContact CG2-CG1 4.14Å; I109-T197 WeakPolarHBondContact CA-O 3.47Å; I109-V198 HydrophobicContact CG2-CG2 4.46Å; I109-I213 HydrophobicContact CD1-CD1 4.41Å; I109-I213 HydrophobicContact CD1-CG2 3.51Å; I109-I213 HydrophobicContact CG1-CG2 3.9Å
110K98.5Very high95.4Very high57 Ų5752.5 Ų52.525%0.24826%0.256CS..EExtended strand (participates in β ladder)trans-119.6124.1175.1178.2-179.660.61480108.5T96 I97 F108 E112 V196 T197T96-K110 CarbonylContact O-C 3.28Å; T96-K110 WeakPolarHBondContact O-CA 3.33Å; I97-K110 HydrophobicContact CG1-CG 4.32Å; F108-K110 HydrophobicContact CD2-CB 4Å; F108-K110 HydrophobicContact CE2-CB 4.09Å; K110-E112 HydrophobicContact CD-CG 4.17Å; K110-E112 VanDerWaalsContact CE-OE2 3.23Å; K110-E112 WeakPolarHBondContact CE-OE2 3.43Å; K110-E112 HydrophobicContact CG-CG 4.08Å; K110-E112 IonicContact NZ-OE2 2.82Å; K110-E112 PolarHBondContact NZ-OE2 2.7Å; K110-V196 CarbonylContact O-C 3.15Å; K110-V196 WeakPolarHBondContact O-CA 3.38Å; K110-T197 PolarHBondContact N-O 3.45Å; K110-T197 PolarHBondContact O-N 3.47Å
111I98.8Very high95.6Very high18 Ų1857.3 Ų57.39%0.09229%0.286CS..EExtended strand (participates in β ladder)trans-114.9113.1177.1-52.1169.6000107T96 I109 K194 L195 V196 E217 F221T96-I111 PolarHBondContact N-O 3.33Å; T96-I111 PolarHBondContact O-N 3.35Å; I109-I111 HydrophobicContact CG2-CG1 4.19Å; I111-K194 HydrophobicContact CG2-CB 4.44Å; I111-L195 WeakPolarHBondContact CA-O 3.15Å; I111-V196 HydrophobicContact CG1-CG2 4.4Å; I111-E217 WeakPolarHBondContact CD1-OE2 3.19Å; I111-F221 HydrophobicContact CD1-CE1 4.47Å; I111-F221 HydrophobicContact CD1-CZ 4.14Å; I111-F221 HydrophobicContact CG2-CZ 4.17Å
112E98.7Very high95.9Very high24 Ų2454.5 Ų54.511%0.11227%0.273CS..EExtended strand (participates in β ladder)trans-107129172.5-65.9179.3101.400107.4Y93 C94 R95 K110 H126 K194 L195Y93-E112 HydrophobicContact CE2-CB 4.28Å; Y93-E112 PolarHBondContact OH-OE1 3.14Å; C94-E112 WeakPolarHBondContact O-CA 3.38Å; R95-E112 HydrophobicContact CG-CG 4.17Å; R95-E112 IonicContact CZ-OE1 3.87Å; R95-E112 IonicContact NE-OE1 2.71Å; R95-E112 PolarHBondContact NE-OE1 2.86Å; R95-E112 IonicContact NH2-OE1 3.21Å; R95-E112 PolarHBondContact NH2-OE1 3.42Å; K110-E112 HydrophobicContact CD-CG 4.17Å; K110-E112 VanDerWaalsContact CE-OE2 3.23Å; K110-E112 WeakPolarHBondContact CE-OE2 3.43Å; K110-E112 HydrophobicContact CG-CG 4.08Å; K110-E112 IonicContact NZ-OE2 2.82Å; K110-E112 PolarHBondContact NZ-OE2 2.7Å; E112-H126 PolarHBondContact O-NE2 3.3Å; E112-K194 CarbonylContact O-C 3.46Å; E112-L195 PolarHBondContact N-O 3.09Å; E112-L195 PolarHBondContact O-N 3.37Å
113T98.8Very high96.3Very high6 Ų654.1 Ų54.14%0.03728%0.275CS..EExtended strand (participates in β ladder)trans-127129.6-176.2-55.60000111.5Y93 C94 H115 A192 Y193 K194Y93-T113 WeakPolarHBondContact CA-O 3.12Å; Y93-T113 VanDerWaalsContact CD2-O 3.28Å; Y93-T113 WeakPolarHBondContact CD2-O 3.49Å; C94-T113 PolarHBondContact N-O 3.27Å; C94-T113 PolarHBondContact O-N 3.42Å; T113-H115 WeakPolarHBondContact CG2-CE1 3.36Å; T113-H115 VanDerWaalsContact CG2-NE2 3.28Å; T113-H115 WeakPolarHBondContact CG2-NE2 3.33Å; T113-A192 HydrophobicContact CG2-CB 4.45Å; T113-Y193 VanDerWaalsContact CA-O 3.27Å; T113-Y193 WeakPolarHBondContact CA-O 3.36Å; T113-K194 HydrophobicContact CG2-CG 3.86Å
114W98.8Very high96.7Very high72 Ų7254.4 Ų54.427%0.27328%0.277SS..EExtended strand (participates in β ladder)trans-106.4130.8160.5-83.9105000110.5P92 Y93 K116 V125 H126 Y193P92-W114 HydrophobicContact CG-CZ3 4.16Å; Y93-W114 AromaticContact CD2-CD1 3.98Å; Y93-W114 AromaticContact CD2-CD2 3.93Å; Y93-W114 HydrophobicContact CD2-CD2 3.93Å; Y93-W114 AromaticContact CD2-CE2 3.58Å; Y93-W114 HydrophobicContact CD2-CG 4.18Å; Y93-W114 AromaticContact CD2-CZ2 3.97Å; Y93-W114 HydrophobicContact CD2-CZ2 3.97Å; Y93-W114 AromaticContact CD2-NE1 3.61Å; Y93-W114 AromaticContact CE2-NE1 3.94Å; Y93-W114 HydrophobicContact CG-CZ2 4.21Å; W114-K116 HydrophobicContact CB-CG 4.39Å; W114-V125 HydrophobicContact CB-CG2 4.22Å; W114-H126 AromaticContact CD1-CD2 3.57Å; W114-H126 AromaticContact CD1-NE2 3.57Å; W114-Y193 PolarHBondContact N-O 3.49Å; W114-Y193 VanDerWaalsContact N-O 3.1Å; W114-Y193 PolarHBondContact O-N 3.05Å
115H98.8Very high97Very high2 Ų247.8 Ų47.81%0.00925%0.25CC..EExtended strand (participates in β ladder)trans-99.2121.4168.2-50.288.3000108Y18 Y91 P92 T113Y18-H115 AromaticContact CD1-CD2 3.54Å; Y18-H115 AromaticContact CD1-NE2 3.91Å; Y18-H115 AromaticContact CE1-CD2 3.2Å; Y18-H115 WeakPolarHBondContact CE1-CD2 3.45Å; Y18-H115 AromaticContact CE1-NE2 3.17Å; Y18-H115 WeakPolarHBondContact CE1-NE2 3.23Å; Y18-H115 AromaticContact CZ-CD2 3.97Å; Y18-H115 AromaticContact CZ-NE2 3.93Å; Y91-H115 AromaticContact CD2-ND1 3.75Å; Y91-H115 HydrophobicContact CE2-CB 3.94Å; Y91-H115 AromaticContact CE2-CE1 3.73Å; Y91-H115 AromaticContact CE2-CG 3.46Å; Y91-H115 VanDerWaalsContact CE2-CG 3.46Å; Y91-H115 AromaticContact CE2-ND1 3.27Å; Y91-H115 VanDerWaalsContact CE2-ND1 3.27Å; Y91-H115 WeakPolarHBondContact CE2-ND1 3.25Å; Y91-H115 AromaticContact CZ-CG 3.91Å; Y91-H115 WeakPolarHBondContact OH-CB 3.41Å; P92-H115 HydrophobicContact CB-CB 4.19Å; P92-H115 PolarHBondContact O-N 3.23Å; P92-H115 PolarHBondContact O-ND1 3.25Å; T113-H115 WeakPolarHBondContact CG2-CE1 3.36Å; T113-H115 VanDerWaalsContact CG2-NE2 3.28Å; T113-H115 WeakPolarHBondContact CG2-NE2 3.33Å
116K98.4Very high97.3Very high47 Ų4742.7 Ų42.720%0.20422%0.222CC..EExtended strand (participates in β ladder)trans-127.6144-175.9-60.2-64.2-172.8-173.10110.6W114 D118 M190 C191 Y193W114-K116 HydrophobicContact CB-CG 4.39Å; K116-D118 PolarHBondContact O-N 3.21Å; K116-M190 CarbonylContact O-C 3.34Å; K116-M190 VanDerWaalsContact O-CA 3.23Å; K116-M190 WeakPolarHBondContact O-CA 3.17Å; K116-M190 WeakPolarHBondContact O-CB 3.28Å; K116-C191 PolarHBondContact N-O 3.36Å; K116-C191 PolarHBondContact O-N 2.83Å; K116-Y193 HydrophobicContact CB-CD2 4.35Å; K116-Y193 HydrophobicContact CB-CE2 3.94Å; K116-Y193 HydrophobicContact CG-CD2 4.05Å; K116-Y193 HydrophobicContact CG-CE2 3.96Å
117P97.1Very high97.6Very high95 Ų9549.2 Ų49.262%0.61724%0.244SC*.SBendtrans-80.859.9178.335.2-36.5000111I15I15-P117 HydrophobicContact CG2-CB 4.25Å
118D96.4Very high97.7Very high22 Ų2250 Ų5012%0.11825%0.249CC..SBendtrans-142-173.8179.369.827.1000112.2K116 G120 Q122 M190 C191 Y193K116-D118 PolarHBondContact O-N 3.21Å; D118-G120 PolarHBondContact OD1-N 2.81Å; D118-Q122 WeakPolarHBondContact OD2-CG 3.49Å; D118-Q122 PolarHBondContact OD2-NE2 3.16Å; D118-M190 CarbonylContact O-C 3.55Å; D118-M190 WeakPolarHBondContact O-CA 3.41Å; D118-C191 PolarHBondContact O-N 3.04Å; D118-C191 VanDerWaalsContact OD1-CB 3.31Å; D118-C191 WeakPolarHBondContact OD1-CB 3.16Å; D118-Y193 WeakPolarHBondContact OD1-CE2 3.3Å; D118-Y193 PolarHBondContact OD1-OH 3.24Å; D118-Y193 VanDerWaalsContact OD1-OH 3.12Å; D118-Y193 PolarHBondContact OD2-OH 2.83Å; D118-Y193 VanDerWaalsContact OD2-OH 3.13Å
119M97.1Very high97.7Very high45 Ų4552.2 Ų52.222%0.22226%0.263CS..SBendtrans-101.723.8-179.3-63.5-61-70.300113.3V10 K178 L181 A182 K189V10-M119 HydrophobicContact CG1-CE 3.66Å; V10-M119 HydrophobicContact CG1-SD 3.96Å; V10-M119 WeakPolarHBondContact CG2-O 3.46Å; M119-K178 HydrophobicContact CE-CB 4.46Å; M119-K178 WeakPolarHBondContact CE-O 3.46Å; M119-L181 HydrophobicContact CE-CB 4.2Å; M119-L181 HydrophobicContact CE-CD2 4.07Å; M119-L181 HydrophobicContact CE-CG 4.17Å; M119-L181 HydrophobicContact SD-CD2 4.17Å; M119-L181 HydrophobicContact SD-CG 4.24Å; M119-A182 HydrophobicContact CE-CB 4.19Å; M119-A182 HydrophobicContact CG-CB 4.44Å; M119-K189 HydrophobicContact CG-CD 4.06Å; M119-K189 HydrophobicContact SD-CB 3.83Å; M119-K189 HydrophobicContact SD-CD 3.56Å; M119-K189 VanDerWaalsContact SD-CD 3.56Å; M119-K189 HydrophobicContact SD-CG 4.04Å
120G97.2Very high97.6Very high8 Ų856.1 Ų56.18%0.08229%0.292CS..SBendtrans83.220.3176.900000115.1R8 D118 C191 Y193R8-G120 WeakPolarHBondContact CD-O 3.27Å; R8-G120 PolarHBondContact NH1-O 3Å; D118-G120 PolarHBondContact OD1-N 2.81Å; G120-C191 WeakPolarHBondContact CA-SG 3.48Å; G120-Y193 WeakPolarHBondContact CA-OH 3.48Å
121T96.2Very high97.4Very high105 Ų10556.7 Ų56.764%0.64430%0.303SS*.  trans-91.1-17.6-173.354.90000114.4E123 Y193T121-E123 PolarHBondContact O-N 3Å; T121-Y193 PolarHBondContact N-OH 3Å; T121-Y193 VanDerWaalsContact N-OH 3.12Å
122Q97.6Very high97.2Very high84 Ų8459.8 Ų59.839%0.39332%0.319SS..  trans-66.6131.3176.7-64-177.957.900112.5R8 D118 V125 Y193R8-Q122 PolarHBondContact NH2-O 3.31Å; D118-Q122 WeakPolarHBondContact OD2-CG 3.49Å; D118-Q122 PolarHBondContact OD2-NE2 3.16Å; Q122-V125 HydrophobicContact CB-CG1 3.3Å; Q122-V125 HydrophobicContact CG-CG1 4.31Å; Q122-Y193 HydrophobicContact CB-CE1 4.39Å; Q122-Y193 WeakPolarHBondContact CB-OH 3.16Å; Q122-Y193 PolarHBondContact N-OH 2.84Å; Q122-Y193 VanDerWaalsContact O-CE1 3.3Å; Q122-Y193 WeakPolarHBondContact O-CE1 3.46Å
123E97.8Very high97.1Very high112 Ų11260.8 Ų60.852%0.52332%0.322SS..SBendtrans-91.5142.3173.6-67.6-54.2128.100111.1R8 T121 V125 W133R8-E123 IonicContact CZ-OE1 3.95Å; R8-E123 VanDerWaalsContact CZ-OE1 3.29Å; R8-E123 IonicContact NH1-OE1 3.48Å; R8-E123 PolarHBondContact NH1-OE1 2.78Å; R8-E123 IonicContact NH2-OE1 3.65Å; R8-E123 PolarHBondContact NH2-OE1 2.87Å; R8-E123 IonicContact NH2-OE2 3.8Å; R8-E123 PolarHBondContact NH2-OE2 3.08Å; R8-E123 VanDerWaalsContact NH2-OE2 3.08Å; T121-E123 PolarHBondContact O-N 3Å; E123-V125 VanDerWaalsContact C-N 3.32Å; E123-V125 PolarHBondContact O-N 3.26Å; E123-W133 WeakPolarHBondContact OE2-CZ2 3.17Å
124N97.2Very high96.9Very high33 Ų3367.8 Ų67.818%0.17635%0.352CS..  trans45.746.9176.6-162.59.8000115.1H126 K127 V128 W133N124-H126 PolarHBondContact O-N 2.82Å; N124-K127 PolarHBondContact O-N 3.4Å; N124-K127 PolarHBondContact OD1-N 3.05Å; N124-V128 PolarHBondContact ND2-O 3.13Å; N124-V128 PolarHBondContact OD1-N 3.27Å; N124-W133 HydrophobicContact CB-CD2 3.62Å; N124-W133 HydrophobicContact CB-CE3 4Å; N124-W133 HydrophobicContact CB-CG 4.05Å; N124-W133 HydrophobicContact CB-CH2 4.32Å; N124-W133 HydrophobicContact CB-CZ2 3.96Å; N124-W133 HydrophobicContact CB-CZ3 4.33Å
125V98.1Very high96.7Very high18 Ų1869.9 Ų69.911%0.10937%0.368CS..THydrogen-bonded Turntrans-58.1-24.5-178.7-61.60000113.5W114 Q122 E123 K127 Y193W114-V125 HydrophobicContact CB-CG2 4.22Å; Q122-V125 HydrophobicContact CB-CG1 3.3Å; Q122-V125 HydrophobicContact CG-CG1 4.31Å; E123-V125 VanDerWaalsContact C-N 3.32Å; E123-V125 PolarHBondContact O-N 3.26Å; V125-K127 VanDerWaalsContact C-N 3.3Å; V125-Y193 HydrophobicContact CG1-CD1 4.05Å; V125-Y193 HydrophobicContact CG1-CE1 3.96Å; V125-Y193 HydrophobicContact CG1-CE2 4.46Å; V125-Y193 HydrophobicContact CG1-CG 4.32Å; V125-Y193 HydrophobicContact CG2-CD1 3.78Å; V125-Y193 HydrophobicContact CG2-CD2 4.39Å; V125-Y193 HydrophobicContact CG2-CG 3.69Å
126H98.1Very high96.7Very high30 Ų3070.4 Ų70.414%0.13937%0.371CS..THydrogen-bonded Turntrans-81.9-6.9177.7-65.792.3000113.4Q6 E112 W114 N124 V128 Y193 L195Q6-H126 PolarHBondContact OE1-ND1 3.02Å; E112-H126 PolarHBondContact O-NE2 3.3Å; W114-H126 AromaticContact CD1-CD2 3.57Å; W114-H126 AromaticContact CD1-NE2 3.57Å; N124-H126 PolarHBondContact O-N 2.82Å; H126-V128 HydrophobicContact CB-CG2 3.95Å; H126-V128 PolarHBondContact O-N 2.98Å; H126-Y193 PolarHBondContact CE1-O 3.5Å; H126-L195 HydrophobicContact CB-CD2 3.88Å
127K97.6Very high96.6Very high186 Ų18670.4 Ų70.481%0.80938%0.381SS*.  trans53.740.9-177-54179.8-179.1179.70112.2N124 V125N124-K127 PolarHBondContact O-N 3.4Å; N124-K127 PolarHBondContact OD1-N 3.05Å; V125-K127 VanDerWaalsContact C-N 3.3Å
128V96.5Very high96.6Very high24 Ų2468.6 Ų68.615%0.14537%0.367CS..  trans-61.1143.1170.71800000108.3N124 H126 S130 I132 W133 L195N124-V128 PolarHBondContact ND2-O 3.13Å; N124-V128 PolarHBondContact OD1-N 3.27Å; H126-V128 HydrophobicContact CB-CG2 3.95Å; H126-V128 PolarHBondContact O-N 2.98Å; V128-S130 PolarHBondContact O-N 3.4Å; V128-I132 HydrophobicContact CG1-CB 3.76Å; V128-I132 HydrophobicContact CG1-CG2 3.67Å; V128-W133 HydrophobicContact CB-CE3 4.27Å; V128-W133 HydrophobicContact CG2-CE3 4.48Å; V128-L195 HydrophobicContact CG2-CD2 3.57Å
129D96Very high96.7Very high95 Ų9568.7 Ų68.751%0.50837%0.369SS..  trans-51.9136.7176.3-179.3-91.6000111.5S131 I132 W133D129-S131 PolarHBondContact O-N 3.27Å; D129-S131 VanDerWaalsContact O-N 3.14Å; D129-S131 WeakPolarHBondContact OD1-CA 3.26Å; D129-S131 WeakPolarHBondContact OD1-CB 3.49Å; D129-S131 PolarHBondContact OD1-N 2.83Å; D129-S131 PolarHBondContact OD1-OG 3.2Å; D129-I132 HydrophobicContact CB-CD1 4.4Å; D129-I132 PolarHBondContact O-N 2.96Å; D129-W133 PolarHBondContact O-N 2.84Å
130S95.4Very high96.8Very high95 Ų9570.6 Ų70.666%0.66439%0.385SS*.Hα-helixtrans-57.3-31.9-174.8-59.90000113.4V128 I132 K134V128-S130 PolarHBondContact O-N 3.4Å; S130-I132 VanDerWaalsContact C-N 3.29Å; S130-I132 PolarHBondContact O-N 2.9Å; S130-K134 PolarHBondContact O-N 3.08Å
131S94.3Very high96.8Very high70 Ų7070.2 Ų70.249%0.4938%0.381SS..Hα-helixtrans-70-26.5178750000112.9D129 K134D129-S131 PolarHBondContact O-N 3.27Å; D129-S131 VanDerWaalsContact O-N 3.14Å; D129-S131 WeakPolarHBondContact OD1-CA 3.26Å; D129-S131 WeakPolarHBondContact OD1-CB 3.49Å; D129-S131 PolarHBondContact OD1-N 2.83Å; D129-S131 PolarHBondContact OD1-OG 3.2Å; S131-K134 WeakPolarHBondContact O-CE 3.2Å; S131-K134 WeakPolarHBondContact O-CG 3.46Å
132I94.4Very high96.9Very high83 Ų8366.6 Ų66.643%0.42636%0.357SS..Hα-helixtrans-87.6-45.1174-60.4173.7000109.4L4 V128 D129 S130 K134 N135 V136L4-I132 HydrophobicContact CD2-CG2 3.98Å; V128-I132 HydrophobicContact CG1-CB 3.76Å; V128-I132 HydrophobicContact CG1-CG2 3.67Å; D129-I132 HydrophobicContact CB-CD1 4.4Å; D129-I132 PolarHBondContact O-N 2.96Å; S130-I132 VanDerWaalsContact C-N 3.29Å; S130-I132 PolarHBondContact O-N 2.9Å; I132-K134 VanDerWaalsContact C-N 3.25Å; I132-K134 PolarHBondContact O-N 2.88Å; I132-N135 PolarHBondContact O-N 3.12Å; I132-V136 HydrophobicContact CG2-CG2 4.48Å
133W96.8Very high97Very high44 Ų4462.6 Ų62.617%0.16734%0.339CS..Hα-helixtrans-54.8-38.1-175.3-179.5-105.9000113.1E123 N124 V128 D129 N135 V136 V138E123-W133 WeakPolarHBondContact OE2-CZ2 3.17Å; N124-W133 HydrophobicContact CB-CD2 3.62Å; N124-W133 HydrophobicContact CB-CE3 4Å; N124-W133 HydrophobicContact CB-CG 4.05Å; N124-W133 HydrophobicContact CB-CH2 4.32Å; N124-W133 HydrophobicContact CB-CZ2 3.96Å; N124-W133 HydrophobicContact CB-CZ3 4.33Å; V128-W133 HydrophobicContact CB-CE3 4.27Å; V128-W133 HydrophobicContact CG2-CE3 4.48Å; D129-W133 PolarHBondContact O-N 2.84Å; W133-N135 PolarHBondContact O-N 3.41Å; W133-V136 HydrophobicContact CD2-CB 4.5Å; W133-V136 HydrophobicContact CE3-CB 3.97Å; W133-V136 HydrophobicContact CE3-CG1 4.2Å; W133-V136 HydrophobicContact CE3-CG2 4Å; W133-V136 HydrophobicContact CH2-CG1 4.45Å; W133-V136 HydrophobicContact CZ3-CB 4.14Å; W133-V136 HydrophobicContact CZ3-CG1 3.87Å; W133-V136 HydrophobicContact CZ3-CG2 4.47Å; W133-V136 WeakPolarHBondContact O-CB 3.41Å; W133-V136 PolarHBondContact O-N 3.24Å; W133-V138 HydrophobicContact CH2-CG2 4.46Å; W133-V138 HydrophobicContact CZ2-CG2 4.45Å
134K95.6Very high97Very high154 Ų15457.9 Ų57.967%0.6732%0.319SS*.THydrogen-bonded Turntrans-56.2-22.3177.471.9-176.2-173.31790114.4S130 S131 I132S130-K134 PolarHBondContact O-N 3.08Å; S131-K134 WeakPolarHBondContact O-CE 3.2Å; S131-K134 WeakPolarHBondContact O-CG 3.46Å; I132-K134 VanDerWaalsContact C-N 3.25Å; I132-K134 PolarHBondContact O-N 2.88Å
135N94.9Very high97.1Very high115 Ų11559 Ų5962%0.61533%0.325SS*.THydrogen-bonded Turntrans-103.8-1.8179.9-62.9-33.8000112.6I132 W133 A137I132-N135 PolarHBondContact O-N 3.12Å; W133-N135 PolarHBondContact O-N 3.41Å; N135-A137 PolarHBondContact O-N 2.74Å
136V97.1Very high97Very high13 Ų1362.6 Ų62.68%0.07934%0.336CS..  trans-79114.4178.8179.20000108.9L4 Q6 I132 W133 V138 L195L4-V136 HydrophobicContact CB-CG2 3.89Å; L4-V136 HydrophobicContact CD2-CG2 4.24Å; Q6-V136 HydrophobicContact CB-CG1 4.05Å; I132-V136 HydrophobicContact CG2-CG2 4.48Å; W133-V136 HydrophobicContact CD2-CB 4.5Å; W133-V136 HydrophobicContact CE3-CB 3.97Å; W133-V136 HydrophobicContact CE3-CG1 4.2Å; W133-V136 HydrophobicContact CE3-CG2 4Å; W133-V136 HydrophobicContact CH2-CG1 4.45Å; W133-V136 HydrophobicContact CZ3-CB 4.14Å; W133-V136 HydrophobicContact CZ3-CG1 3.87Å; W133-V136 HydrophobicContact CZ3-CG2 4.47Å; W133-V136 WeakPolarHBondContact O-CB 3.41Å; W133-V136 PolarHBondContact O-N 3.24Å; V136-V138 PolarHBondContact O-N 2.96Å; V136-L195 HydrophobicContact CG1-CD1 4Å
137A96.9Very high97Very high48 Ų4866 Ų6640%0.39736%0.363SS..EExtended strand (participates in β ladder)trans-72.8128.1173.200000110.5K5 Q6 N135K5-A137 CarbonylContact C-O 3.52Å; K5-A137 WeakPolarHBondContact CA-O 3.23Å; K5-A137 HydrophobicContact CG-CB 4.29Å; Q6-A137 PolarHBondContact N-O 3.18Å; N135-A137 PolarHBondContact O-N 2.74Å
138V98.1Very high97Very high56 Ų5659.4 Ų59.434%0.33934%0.336SS..EExtended strand (participates in β ladder)trans-86.9121.6170.3178.50000108.7Q6 R8 W133 V136Q6-V138 WeakPolarHBondContact O-CA 3.17Å; R8-V138 HydrophobicContact CG-CG1 4.11Å; W133-V138 HydrophobicContact CH2-CG2 4.46Å; W133-V138 HydrophobicContact CZ2-CG2 4.45Å; V136-V138 PolarHBondContact O-N 2.96Å
139V98.2Very high97Very high25 Ų2558.7 Ų58.715%0.15233%0.331CS..EExtended strand (participates in β ladder)trans-114.4102.8-176.1-176.70000108.8K5 Q6 N7 R8 K218K5-V139 HydrophobicContact CB-CG2 4.35Å; K5-V139 HydrophobicContact CD-CG2 4.33Å; Q6-V139 PolarHBondContact O-N 2.79Å; N7-V139 CarbonylContact C-O 3.59Å; N7-V139 VanDerWaalsContact CA-O 3.25Å; N7-V139 WeakPolarHBondContact CA-O 3.48Å; N7-V139 WeakPolarHBondContact OD1-CB 3.23Å; N7-V139 WeakPolarHBondContact OD1-CG1 3.46Å; R8-V139 PolarHBondContact N-O 2.95Å; V139-K218 HydrophobicContact CG1-CD 3.93Å; V139-K218 HydrophobicContact CG1-CG 4.36Å
140P98Very high96.9Very high85 Ų8556.1 Ų56.155%0.55232%0.321SS*.EExtended strand (participates in β ladder)trans-70.1138.2173.529-32.7000109.9
141I98.7Very high96.9Very high0 Ų055.8 Ų55.80%032%0.324CS..EExtended strand (participates in β ladder)trans-112.4126.3168.6-63.9-178.9000107.5N7 R8 V9 K218 F221N7-I141 HydrophobicContact CB-CD1 4.02Å; R8-I141 PolarHBondContact O-N 2.91Å; V9-I141 HydrophobicContact CG1-CB 4.46Å; V9-I141 HydrophobicContact CG1-CG2 4.31Å; V9-I141 HydrophobicContact CG2-CB 4.09Å; V9-I141 HydrophobicContact CG2-CD1 4.06Å; V9-I141 HydrophobicContact CG2-CG1 4.49Å; V9-I141 HydrophobicContact CG2-CG2 4.49Å; I141-K218 HydrophobicContact CD1-CG 4.3Å; I141-K218 HydrophobicContact CG1-CG 4.48Å; I141-F221 HydrophobicContact CD1-CB 3.47Å; I141-F221 VanDerWaalsContact CD1-CB 3.47Å; I141-F221 HydrophobicContact CD1-CD2 4.21Å; I141-F221 HydrophobicContact CD1-CG 4.37Å
142D98.5Very high96.7Very high29 Ų2957 Ų5716%0.15533%0.333CS..  trans-112.3109.9174-162.3-31.3000109.6A144 D145 W177 K178D142-A144 PolarHBondContact O-N 3.48Å; D142-A144 PolarHBondContact OD1-N 2.8Å; D142-A144 VanDerWaalsContact OD1-N 3.08Å; D142-D145 HydrophobicContact CB-CB 3.69Å; D142-D145 PolarHBondContact O-N 2.9Å; D142-W177 PolarHBondContact OD1-NE1 3.26Å; D142-K178 VanDerWaalsContact CB-NZ 3.31Å; D142-K178 IonicContact OD1-NZ 3.58Å; D142-K178 WeakPolarHBondContact OD2-CE 3.44Å; D142-K178 IonicContact OD2-NZ 2.83Å; D142-K178 PolarHBondContact OD2-NZ 2.84Å
143I98.6Very high96.7Very high0 Ų054 Ų540%032%0.317CS..THydrogen-bonded Turntrans-68.6-18.7-176.360.1163.1000112.7V9 L11 P160 L173 W177 H225 R226 F229V9-I143 HydrophobicContact CG1-CG2 4.12Å; L11-I143 HydrophobicContact CD2-CD1 3.82Å; L11-I143 HydrophobicContact CD2-CG2 4.26Å; I143-P160 HydrophobicContact CB-CG 4.32Å; I143-P160 HydrophobicContact CD1-CB 4.47Å; I143-P160 HydrophobicContact CD1-CG 4.31Å; I143-P160 HydrophobicContact CG1-CG 4.49Å; I143-P160 WeakPolarHBondContact O-CG 3.48Å; I143-L173 HydrophobicContact CD1-CD1 3.56Å; I143-L173 HydrophobicContact CG1-CD1 3.85Å; I143-W177 HydrophobicContact CG1-CH2 4.34Å; I143-W177 HydrophobicContact CG1-CZ2 3.97Å; I143-H225 HydrophobicContact CG2-CB 3.62Å; I143-R226 HydrophobicContact CB-CG 3.95Å; I143-R226 HydrophobicContact CG2-CG 4.38Å; I143-R226 VanDerWaalsContact O-CG 3.28Å; I143-R226 WeakPolarHBondContact O-CG 3.47Å; I143-R226 PolarHBondContact O-NH1 2.81Å; I143-F229 HydrophobicContact CD1-CB 4.05Å; I143-F229 HydrophobicContact CD1-CG 4.27Å
144A98.4Very high96.7Very high13 Ų1355.1 Ų55.111%0.10732%0.322CS..THydrogen-bonded Turntrans-90.6-16.1176.300000113.2D142 R146 L173D142-A144 PolarHBondContact O-N 3.48Å; D142-A144 PolarHBondContact OD1-N 2.8Å; D142-A144 VanDerWaalsContact OD1-N 3.08Å; A144-R146 PolarHBondContact O-N 3.07Å; A144-L173 HydrophobicContact CB-CB 3.68Å; A144-L173 WeakPolarHBondContact CB-O 3.24Å
145D98.2Very high96.7Very high56 Ų5651.9 Ų51.930%0.29931%0.308SS..  trans-79.9103.2-175.3-178.4-1.2000111.4D142 S147 Q148D142-D145 HydrophobicContact CB-CB 3.69Å; D142-D145 PolarHBondContact O-N 2.9Å; D145-S147 VanDerWaalsContact CG-OG 3.22Å; D145-S147 PolarHBondContact O-N 2.86Å; D145-S147 VanDerWaalsContact O-N 3.11Å; D145-S147 VanDerWaalsContact OD1-CB 3.29Å; D145-S147 WeakPolarHBondContact OD1-CB 3.08Å; D145-S147 PolarHBondContact OD1-N 2.94Å; D145-S147 PolarHBondContact OD1-OG 3.26Å; D145-S147 PolarHBondContact OD2-OG 2.87Å; D145-Q148 HydrophobicContact CB-CG 4.16Å; D145-Q148 PolarHBondContact O-N 2.84Å; D145-Q148 WeakPolarHBondContact OD2-CG 3.37Å; D145-Q148 PolarHBondContact OD2-NE2 2.82Å
146R97.4Very high96.8Very high93 Ų9350.5 Ų50.535%0.35131%0.305SS..G310 helixtrans-55.5-29177.9179.860.8-17185.8-8.3113.1A144 Q148 V149 Y154A144-R146 PolarHBondContact O-N 3.07Å; R146-Q148 PolarHBondContact O-N 2.93Å; R146-V149 PolarHBondContact NH1-O 3.23Å; R146-V149 PolarHBondContact O-N 2.69Å; R146-Y154 VanDerWaalsContact CD-CD2 3.43Å; R146-Y154 VanDerWaalsContact CD-CE2 3.4Å; R146-Y154 VanDerWaalsContact NH2-CG 3.34Å
147S97.3Very high96.7Very high101 Ų10155.2 Ų55.271%0.70633%0.33SS*.G310 helixtrans-69.9-17.8-178.876.80000113.4D145 V149D145-S147 VanDerWaalsContact CG-OG 3.22Å; D145-S147 PolarHBondContact O-N 2.86Å; D145-S147 VanDerWaalsContact O-N 3.11Å; D145-S147 VanDerWaalsContact OD1-CB 3.29Å; D145-S147 WeakPolarHBondContact OD1-CB 3.08Å; D145-S147 PolarHBondContact OD1-N 2.94Å; D145-S147 PolarHBondContact OD1-OG 3.26Å; D145-S147 PolarHBondContact OD2-OG 2.87Å; S147-V149 VanDerWaalsContact C-N 3.3Å
148Q97.6Very high96.7Very high49 Ų4953.8 Ų53.823%0.22932%0.315CS..G310 helixtrans-85.9-2.4177.8-63.8-177.636.200113.5D145 R146 T222D145-Q148 HydrophobicContact CB-CG 4.16Å; D145-Q148 PolarHBondContact O-N 2.84Å; D145-Q148 WeakPolarHBondContact OD2-CG 3.37Å; D145-Q148 PolarHBondContact OD2-NE2 2.82Å; R146-Q148 PolarHBondContact O-N 2.93Å; Q148-T222 HydrophobicContact CB-CG2 4.33Å
149V97Very high96.8Very high8 Ų851.4 Ų51.45%0.04830%0.3CS..SBendtrans-111.8131.1-178.9-172.20000109.1R146 S147 D153 T222R146-V149 PolarHBondContact NH1-O 3.23Å; R146-V149 PolarHBondContact O-N 2.69Å; S147-V149 VanDerWaalsContact C-N 3.3Å; V149-D153 HydrophobicContact CG1-CB 4.02Å; V149-T222 HydrophobicContact CG2-CG2 3.93Å
150S94.3Very high96.8Very high41 Ų4150.2 Ų50.229%0.28729%0.293SS..  trans-66.4159.8176.175.30000111.2S152 D153 Y154S150-S152 VanDerWaalsContact C-N 3.27Å; S150-S152 PolarHBondContact O-N 2.85Å; S150-S152 PolarHBondContact OG-OG 2.88Å; S150-S152 VanDerWaalsContact OG-OG 3.05Å; S150-D153 PolarHBondContact O-N 2.75Å; S150-D153 WeakPolarHBondContact OG-CB 3.29Å; S150-D153 PolarHBondContact OG-N 2.7Å; S150-D153 VanDerWaalsContact OG-N 3.13Å; S150-D153 PolarHBondContact OG-OD2 3.41Å; S150-Y154 PolarHBondContact O-N 3.23Å
151A94Very high96.8Very high88 Ų8847.6 Ų47.673%0.72728%0.279SS*.THydrogen-bonded Turntrans-62.6-35.8174.800000112.3
152S91.7Very high96.8Very high97 Ų9752.8 Ų52.868%0.67831%0.306SS*.THydrogen-bonded Turntrans-72.9-24.9-180520000114S150S150-S152 VanDerWaalsContact C-N 3.27Å; S150-S152 PolarHBondContact O-N 2.85Å; S150-S152 PolarHBondContact OG-OG 2.88Å; S150-S152 VanDerWaalsContact OG-OG 3.05Å
153D93.8Very high96.8Very high19 Ų1953.2 Ų53.210%0.10231%0.307CS..THydrogen-bonded Turntrans-91.6-15.7179.2-60.9-29.1000113.1V149 S150 K155 R219 N223V149-D153 HydrophobicContact CG1-CB 4.02Å; S150-D153 PolarHBondContact O-N 2.75Å; S150-D153 WeakPolarHBondContact OG-CB 3.29Å; S150-D153 PolarHBondContact OG-N 2.7Å; S150-D153 VanDerWaalsContact OG-N 3.13Å; S150-D153 PolarHBondContact OG-OD2 3.41Å; D153-K155 PolarHBondContact O-N 3.21Å; D153-R219 IonicContact OD1-CZ 3.08Å; D153-R219 IonicContact OD1-NE 2.81Å; D153-R219 PolarHBondContact OD1-NE 3.15Å; D153-R219 IonicContact OD1-NH2 2.87Å; D153-R219 PolarHBondContact OD1-NH2 2.93Å; D153-R219 IonicContact OD2-CZ 3.56Å; D153-R219 IonicContact OD2-NE 3.29Å; D153-R219 PolarHBondContact OD2-NE 2.87Å; D153-R219 IonicContact OD2-NH2 3.29Å; D153-R219 PolarHBondContact OD2-NH2 2.95Å; D153-N223 VanDerWaalsContact CG-ND2 3.31Å; D153-N223 PolarHBondContact OD2-ND2 3.15Å
154Y96.5Very high96.7Very high67 Ų6759.3 Ų59.326%0.26333%0.334SS..  trans-72122.5-171.7178.2-101.6000111.6R146 S150 P156 D159R146-Y154 VanDerWaalsContact CD-CD2 3.43Å; R146-Y154 VanDerWaalsContact CD-CE2 3.4Å; R146-Y154 VanDerWaalsContact NH2-CG 3.34Å; S150-Y154 PolarHBondContact O-N 3.23Å; Y154-P156 HydrophobicContact CE1-CG 4.01Å; Y154-D159 HydrophobicContact CE2-CB 4.07Å; Y154-D159 WeakPolarHBondContact CE2-OD2 3.33Å; Y154-D159 PolarHBondContact OH-OD2 2.9Å
155K95.6Very high96.7Very high86 Ų8658.9 Ų58.937%0.37433%0.329SS..  trans-124.3128.1169.5-49.9-171.2-152.1151.70109.6D153 D157 E158 D159D153-K155 PolarHBondContact O-N 3.21Å; K155-D157 VanDerWaalsContact C-N 3.25Å; K155-D157 WeakPolarHBondContact CB-OD1 3.44Å; K155-D157 PolarHBondContact O-N 2.99Å; K155-E158 HydrophobicContact CB-CB 4.2Å; K155-E158 HydrophobicContact CB-CG 4.19Å; K155-E158 HydrophobicContact CD-CG 4.41Å; K155-E158 IonicContact NZ-OE1 2.73Å; K155-E158 PolarHBondContact NZ-OE1 2.68Å; K155-E158 IonicContact NZ-OE2 3.32Å; K155-E158 PolarHBondContact NZ-OE2 2.86Å; K155-E158 CarbonylContact O-C 3.58Å; K155-E158 PolarHBondContact O-N 3.43Å; K155-E158 VanDerWaalsContact O-N 3.07Å; K155-D159 PolarHBondContact O-N 3.46Å
156P96.4Very high96.7Very high86 Ų8662.7 Ų62.756%0.55835%0.354SS*.G310 helixtrans-59-32.9-178.6-25.934.2000114.4Y154 E158 D159Y154-P156 HydrophobicContact CE1-CG 4.01Å; P156-E158 VanDerWaalsContact C-N 3.28Å; P156-E158 PolarHBondContact O-N 3.32Å; P156-D159 PolarHBondContact O-N 3.41Å
157D96.4Very high96.7Very high113 Ų11363.8 Ų63.860%0.60436%0.362SS*.G310 helixtrans-78.4-9.8178.461.4-49.2000113.7K155K155-D157 VanDerWaalsContact C-N 3.25Å; K155-D157 WeakPolarHBondContact CB-OD1 3.44Å; K155-D157 PolarHBondContact O-N 2.99Å
158E97.3Very high96.7Very high17 Ų1761.1 Ų61.18%0.07934%0.341CS..G310 helixtrans-11226.5172.9-57.5175.317900110.6K155 P156 P160 R226 Q227K155-E158 HydrophobicContact CB-CB 4.2Å; K155-E158 HydrophobicContact CB-CG 4.19Å; K155-E158 HydrophobicContact CD-CG 4.41Å; K155-E158 IonicContact NZ-OE1 2.73Å; K155-E158 PolarHBondContact NZ-OE1 2.68Å; K155-E158 IonicContact NZ-OE2 3.32Å; K155-E158 PolarHBondContact NZ-OE2 2.86Å; K155-E158 CarbonylContact O-C 3.58Å; K155-E158 PolarHBondContact O-N 3.43Å; K155-E158 VanDerWaalsContact O-N 3.07Å; P156-E158 VanDerWaalsContact C-N 3.28Å; P156-E158 PolarHBondContact O-N 3.32Å; E158-P160 WeakPolarHBondContact O-CD 3.47Å; E158-R226 PolarHBondContact O-NE 2.88Å; E158-R226 PolarHBondContact O-NH2 3.47Å; E158-Q227 HydrophobicContact CB-CG 4.14Å; E158-Q227 VanDerWaalsContact CD-NE2 3.34Å; E158-Q227 HydrophobicContact CG-CG 3.94Å; E158-Q227 PolarHBondContact OE1-NE2 2.71Å; E158-Q227 WeakPolarHBondContact OE2-CG 3.3Å; E158-Q227 PolarHBondContact OE2-NE2 3.39Å
159D98.4Very high96.6Very high6 Ų660.8 Ų60.83%0.03235%0.351CS..  trans-104.9106.4177.3-164.59.8000113.6Y154 K155 P156 A161 N162 F163 R226 C230Y154-D159 HydrophobicContact CE2-CB 4.07Å; Y154-D159 WeakPolarHBondContact CE2-OD2 3.33Å; Y154-D159 PolarHBondContact OH-OD2 2.9Å; K155-D159 PolarHBondContact O-N 3.46Å; P156-D159 PolarHBondContact O-N 3.41Å; D159-A161 PolarHBondContact O-N 2.74Å; D159-A161 VanDerWaalsContact O-N 3.1Å; D159-A161 PolarHBondContact OD1-N 3.36Å; D159-N162 HydrophobicContact CB-CB 4.32Å; D159-N162 CarbonylContact O-C 3.52Å; D159-N162 PolarHBondContact O-N 3.42Å; D159-N162 PolarHBondContact OD2-ND2 3.31Å; D159-F163 WeakPolarHBondContact O-CB 3.34Å; D159-F163 PolarHBondContact O-N 3.06Å; D159-R226 VanDerWaalsContact CA-NH2 3.27Å; D159-R226 IonicContact OD1-CZ 3.8Å; D159-R226 VanDerWaalsContact OD1-CZ 3.29Å; D159-R226 IonicContact OD1-NH1 2.81Å; D159-R226 PolarHBondContact OD1-NH1 3.05Å; D159-R226 IonicContact OD1-NH2 2.7Å; D159-R226 PolarHBondContact OD1-NH2 2.73Å; D159-R226 IonicContact OD2-NH2 2.75Å; D159-C230 VanDerWaalsContact C-SG 3.56Å
160P98.6Very high96.5Very high0 Ų062.3 Ų62.30%036%0.356CS..THydrogen-bonded Turntrans-56.4-26.4175.8-29.738.7000114.5I143 E158 N162 L173 R226 F229I143-P160 HydrophobicContact CB-CG 4.32Å; I143-P160 HydrophobicContact CD1-CB 4.47Å; I143-P160 HydrophobicContact CD1-CG 4.31Å; I143-P160 HydrophobicContact CG1-CG 4.49Å; I143-P160 WeakPolarHBondContact O-CG 3.48Å; E158-P160 WeakPolarHBondContact O-CD 3.47Å; P160-N162 PolarHBondContact O-N 3.27Å; P160-L173 HydrophobicContact CB-CB 4.31Å; P160-L173 HydrophobicContact CB-CD1 3.67Å; P160-L173 HydrophobicContact CB-CG 4.02Å; P160-L173 PolarHBondContact O-N 2.9Å; P160-R226 HydrophobicContact CG-CB 4.06Å; P160-R226 HydrophobicContact CG-CG 3.98Å; P160-F229 HydrophobicContact CB-CD1 3.5Å; P160-F229 HydrophobicContact CB-CE1 3.9Å; P160-F229 HydrophobicContact CB-CG 4.41Å; P160-F229 HydrophobicContact CG-CB 4.39Å; P160-F229 HydrophobicContact CG-CD1 3.88Å
161A98.3Very high96.6Very high30 Ų3061.2 Ų61.225%0.24835%0.351CS..THydrogen-bonded Turntrans-71.5-16.9175.700000113D159 P172D159-A161 PolarHBondContact O-N 2.74Å; D159-A161 VanDerWaalsContact O-N 3.1Å; D159-A161 PolarHBondContact OD1-N 3.36Å; A161-P172 WeakPolarHBondContact O-CB 3.36Å
162N97.8Very high96.8Very high109 Ų10959.5 Ų59.558%0.58333%0.333SS*.THydrogen-bonded Turntrans-115.6-6.8178.8-64.1-46.4000113.1D159 P160D159-N162 HydrophobicContact CB-CB 4.32Å; D159-N162 CarbonylContact O-C 3.52Å; D159-N162 PolarHBondContact O-N 3.42Å; D159-N162 PolarHBondContact OD2-ND2 3.31Å; P160-N162 PolarHBondContact O-N 3.27Å
163F98.5Very high97.1Very high38 Ų3855.4 Ų55.417%0.16730%0.303CS..  trans-98.4131.4-175.3175-94.2000112.2D159 G171 P172 F229 C230 I232D159-F163 WeakPolarHBondContact O-CB 3.34Å; D159-F163 PolarHBondContact O-N 3.06Å; F163-G171 WeakPolarHBondContact O-CA 3.33Å; F163-P172 WeakPolarHBondContact O-CA 3.37Å; F163-F229 HydrophobicContact CD1-CD1 4.01Å; F163-F229 AromaticContact CD1-CE1 3.73Å; F163-F229 HydrophobicContact CD1-CE1 3.73Å; F163-F229 HydrophobicContact CD1-CZ 4.45Å; F163-F229 HydrophobicContact CE1-CE1 4.45Å; F163-C230 HydrophobicContact CB-CB 4.44Å; F163-C230 HydrophobicContact CD1-CB 4.46Å; F163-C230 HydrophobicContact CD2-CB 4.25Å; F163-C230 WeakPolarHBondContact CE2-O 3.43Å; F163-C230 HydrophobicContact CG-CB 4.11Å; F163-C230 VanDerWaalsContact CZ-O 3.25Å; F163-C230 WeakPolarHBondContact CZ-O 3.49Å; F163-I232 HydrophobicContact CE1-CG2 3.64Å; F163-I232 HydrophobicContact CZ-CG2 3.95Å
164K98.2Very high97.2Very high129 Ų12959.6 Ų59.656%0.56132%0.322SS*.  trans-125122.2169.1-177.4164.6-171.3172.70110.1V166 G169 R170 G171K164-V166 PolarHBondContact O-N 2.91Å; K164-G169 WeakPolarHBondContact CE-O 3.46Å; K164-R170 WeakPolarHBondContact CA-O 3.49Å; K164-G171 WeakPolarHBondContact CD-O 3.29Å; K164-G171 VanDerWaalsContact CG-O 3.27Å; K164-G171 WeakPolarHBondContact CG-O 3.18Å
165S98.1Very high97.2Very high3 Ų362 Ų622%0.02135%0.346CS..  trans-64.7128.9176.21670000110.7K167 T168 G169 R170 D233S165-K167 PolarHBondContact OG-N 3.08Å; S165-T168 WeakPolarHBondContact CB-OG1 3.39Å; S165-T168 WeakPolarHBondContact OG-CB 3.12Å; S165-T168 PolarHBondContact OG-N 2.65Å; S165-T168 PolarHBondContact OG-OG1 3.15Å; S165-G169 WeakPolarHBondContact O-CA 3.4Å; S165-G169 PolarHBondContact O-N 2.89Å; S165-R170 PolarHBondContact N-O 2.89Å; S165-D233 WeakPolarHBondContact CA-OD2 3.39Å; S165-D233 WeakPolarHBondContact CB-OD1 3.47Å; S165-D233 PolarHBondContact OG-OD1 2.9Å
166V98.3Very high97.2Very high136 Ų13661 Ų6182%0.82435%0.347SS*.THydrogen-bonded Turntrans-75.5-34.2174.8179.50000110.6K164 D233K164-V166 PolarHBondContact O-N 2.91Å; V166-D233 PolarHBondContact N-OD1 3.11Å; V166-D233 PolarHBondContact N-OD2 2.82Å
167K97.8Very high97.2Very high117 Ų11757.5 Ų57.551%0.50932%0.322SS..THydrogen-bonded Turntrans-79.7-36.5-176.6-63.9-173.3174.7179.30113.6S165 D233 V236 D237S165-K167 PolarHBondContact OG-N 3.08Å; K167-D233 WeakPolarHBondContact CB-OD1 3.32Å; K167-D233 HydrophobicContact CD-CB 4.28Å; K167-D233 WeakPolarHBondContact CD-O 3.38Å; K167-D233 WeakPolarHBondContact CE-O 3.16Å; K167-D233 HydrophobicContact CG-CB 4.31Å; K167-D233 PolarHBondContact N-OD1 2.7Å; K167-D233 VanDerWaalsContact N-OD1 3.08Å; K167-D233 PolarHBondContact NZ-O 2.81Å; K167-V236 HydrophobicContact CB-CG1 4.28Å; K167-V236 HydrophobicContact CD-CG1 3.95Å; K167-D237 VanDerWaalsContact CD-OD2 3.23Å; K167-D237 WeakPolarHBondContact CD-OD2 3.26Å; K167-D237 VanDerWaalsContact CE-OD2 3.31Å; K167-D237 WeakPolarHBondContact CE-OD2 3.41Å; K167-D237 IonicContact NZ-OD2 3.47Å; K167-D237 PolarHBondContact NZ-OD2 3.29Å
168T95.7Very high97.2Very high45 Ų4554.6 Ų54.628%0.27631%0.305SS..THydrogen-bonded Turntrans-109.5-16.1-173.971.50000113.4S165 R170 I232 V236S165-T168 WeakPolarHBondContact CB-OG1 3.39Å; S165-T168 WeakPolarHBondContact OG-CB 3.12Å; S165-T168 PolarHBondContact OG-N 2.65Å; S165-T168 PolarHBondContact OG-OG1 3.15Å; T168-R170 PolarHBondContact O-N 2.83Å; T168-R170 WeakPolarHBondContact OG1-CB 3.46Å; T168-R170 VanDerWaalsContact OG1-CG 3.31Å; T168-R170 WeakPolarHBondContact OG1-CG 3.44Å; T168-R170 PolarHBondContact OG1-N 2.77Å; T168-I232 HydrophobicContact CG2-CD1 4.17Å; T168-I232 HydrophobicContact CG2-CG1 4.37Å; T168-V236 HydrophobicContact CG2-CB 4.48Å; T168-V236 HydrophobicContact CG2-CG1 4.23Å; T168-V236 HydrophobicContact CG2-CG2 3.92Å
169G95.8Very high97.1Very high42 Ų4259.8 Ų59.843%0.43333%0.329SS..  trans71.9-0.9-173.300000114.9K164 S165K164-G169 WeakPolarHBondContact CE-O 3.46Å; S165-G169 WeakPolarHBondContact O-CA 3.4Å; S165-G169 PolarHBondContact O-N 2.89Å
170R95.8Very high96.9Very high40 Ų4063.2 Ų63.215%0.15135%0.347CS..  trans-69.8144.8180-61.5176.5-162.1168.412.6111.3P12 E17 K164 S165 T168 F229P12-R170 WeakPolarHBondContact O-CD 3.32Å; P12-R170 PolarHBondContact O-NH1 3.11Å; E17-R170 IonicContact OE1-CZ 3.42Å; E17-R170 IonicContact OE1-NH1 3.36Å; E17-R170 PolarHBondContact OE1-NH1 3.15Å; E17-R170 IonicContact OE1-NH2 3.11Å; E17-R170 PolarHBondContact OE1-NH2 2.83Å; E17-R170 IonicContact OE2-CZ 3.51Å; E17-R170 IonicContact OE2-NH1 2.74Å; E17-R170 PolarHBondContact OE2-NH1 3.14Å; E17-R170 IonicContact OE2-NH2 2.84Å; E17-R170 PolarHBondContact OE2-NH2 2.94Å; K164-R170 WeakPolarHBondContact CA-O 3.49Å; S165-R170 PolarHBondContact N-O 2.89Å; T168-R170 PolarHBondContact O-N 2.83Å; T168-R170 WeakPolarHBondContact OG1-CB 3.46Å; T168-R170 VanDerWaalsContact OG1-CG 3.31Å; T168-R170 WeakPolarHBondContact OG1-CG 3.44Å; T168-R170 PolarHBondContact OG1-N 2.77Å; R170-F229 HydrophobicContact CB-CE2 4.26Å; R170-F229 HydrophobicContact CB-CZ 4.38Å
171G96Very high96.7Very high17 Ų1763.6 Ų63.618%0.17535%0.349CS..  trans81.8171.7-174.800000113.3F163 K164F163-G171 WeakPolarHBondContact O-CA 3.33Å; K164-G171 WeakPolarHBondContact CD-O 3.29Å; K164-G171 VanDerWaalsContact CG-O 3.27Å; K164-G171 WeakPolarHBondContact CG-O 3.18Å
172P97.8Very high96.4Very high53 Ų5364.7 Ų64.734%0.34436%0.358SS..  cis-62.5152.9-6.428-34000113A161 F163 E174A161-P172 WeakPolarHBondContact O-CB 3.36Å; F163-P172 WeakPolarHBondContact O-CA 3.37Å; P172-E174 PolarHBondContact O-N 2.97Å
173L98Very high96.1Very high11 Ų1164 Ų646%0.05836%0.361CS..  trans-86.796.1177.2-58.2-172000109.8P12 I143 A144 P160 W177 F229P12-L173 HydrophobicContact CG-CD1 4.36Å; P12-L173 HydrophobicContact CG-CD2 4.21Å; I143-L173 HydrophobicContact CD1-CD1 3.56Å; I143-L173 HydrophobicContact CG1-CD1 3.85Å; A144-L173 HydrophobicContact CB-CB 3.68Å; A144-L173 WeakPolarHBondContact CB-O 3.24Å; P160-L173 HydrophobicContact CB-CB 4.31Å; P160-L173 HydrophobicContact CB-CD1 3.67Å; P160-L173 HydrophobicContact CB-CG 4.02Å; P160-L173 PolarHBondContact O-N 2.9Å; L173-W177 HydrophobicContact CB-CB 4.11Å; L173-W177 HydrophobicContact CB-CD2 4.34Å; L173-W177 HydrophobicContact CB-CG 3.93Å; L173-W177 HydrophobicContact CD1-CD2 4.14Å; L173-W177 HydrophobicContact CD1-CE3 4.29Å; L173-W177 HydrophobicContact CD1-CZ2 4.47Å; L173-W177 HydrophobicContact CD2-CB 4.27Å; L173-W177 HydrophobicContact CD2-CD2 4.29Å; L173-W177 HydrophobicContact CD2-CE3 4.14Å; L173-W177 HydrophobicContact CD2-CG 4.39Å; L173-W177 HydrophobicContact CG-CD2 4.5Å; L173-F229 HydrophobicContact CD1-CD1 4.26Å; L173-F229 HydrophobicContact CD1-CE1 4.04Å; L173-F229 HydrophobicContact CD1-CE2 4.5Å; L173-F229 HydrophobicContact CD1-CZ 4.17Å; L173-F229 HydrophobicContact CD2-CE1 4.29Å; L173-F229 HydrophobicContact CD2-CE2 4.36Å; L173-F229 HydrophobicContact CD2-CZ 3.82Å; L173-F229 HydrophobicContact CG-CE1 3.82Å; L173-F229 HydrophobicContact CG-CZ 3.88Å
174E96Very high95.4Very high107 Ų10764.9 Ų64.950%0.537%0.37SS..  trans-69164.2175.6-64.4-61.6160.700112.1P172 T176 W177P172-E174 PolarHBondContact O-N 2.97Å; E174-T176 PolarHBondContact O-N 2.84Å; E174-W177 WeakPolarHBondContact O-CB 3.35Å; E174-W177 PolarHBondContact O-N 3.32Å
175P95.7Very high94.5Very high118 Ų11865 Ų6577%0.76638%0.382SS*.THydrogen-bonded Turntrans-53.6-26.5-179.3-29.236.5000115.4
176T95.8Very high93.7Very high64 Ų6472.2 Ų72.239%0.39342%0.42SS..THydrogen-bonded Turntrans-93.14178.856.70000114.2E174 K178 Q179 D180E174-T176 PolarHBondContact O-N 2.84Å; T176-K178 PolarHBondContact O-N 3.02Å; T176-Q179 VanDerWaalsContact CA-OE1 3.23Å; T176-Q179 WeakPolarHBondContact O-CA 3.48Å; T176-Q179 WeakPolarHBondContact O-CB 3.5Å; T176-Q179 PolarHBondContact O-N 2.78Å; T176-Q179 PolarHBondContact O-OE1 2.95Å; T176-D180 PolarHBondContact O-N 3.49Å; T176-D180 VanDerWaalsContact O-N 3.12Å; T176-D180 PolarHBondContact OG1-OD2 2.96Å
177W97.1Very high93Very high12 Ų1267.3 Ų67.35%0.04539%0.392CS..Hα-helixtrans-53.6-32.6-168.475.9-86000114.2V10 P12 D142 I143 L173 E174 L181V10-W177 HydrophobicContact CB-CH2 4.34Å; V10-W177 HydrophobicContact CG1-CH2 4.05Å; V10-W177 HydrophobicContact CG1-CZ3 4.34Å; V10-W177 WeakPolarHBondContact O-CH2 3.38Å; P12-W177 HydrophobicContact CB-CZ3 4.33Å; P12-W177 HydrophobicContact CG-CZ3 4.29Å; D142-W177 PolarHBondContact OD1-NE1 3.26Å; I143-W177 HydrophobicContact CG1-CH2 4.34Å; I143-W177 HydrophobicContact CG1-CZ2 3.97Å; L173-W177 HydrophobicContact CB-CB 4.11Å; L173-W177 HydrophobicContact CB-CD2 4.34Å; L173-W177 HydrophobicContact CB-CG 3.93Å; L173-W177 HydrophobicContact CD1-CD2 4.14Å; L173-W177 HydrophobicContact CD1-CE3 4.29Å; L173-W177 HydrophobicContact CD1-CZ2 4.47Å; L173-W177 HydrophobicContact CD2-CB 4.27Å; L173-W177 HydrophobicContact CD2-CD2 4.29Å; L173-W177 HydrophobicContact CD2-CE3 4.14Å; L173-W177 HydrophobicContact CD2-CG 4.39Å; L173-W177 HydrophobicContact CG-CD2 4.5Å; E174-W177 WeakPolarHBondContact O-CB 3.35Å; E174-W177 PolarHBondContact O-N 3.32Å; W177-L181 HydrophobicContact CE3-CB 4.48Å; W177-L181 HydrophobicContact CE3-CD2 4.14Å; W177-L181 HydrophobicContact CZ3-CD2 3.65Å; W177-L181 WeakPolarHBondContact O-CB 3.35Å; W177-L181 PolarHBondContact O-N 3.01Å
178K96.3Very high92.8Very high53 Ų5363.5 Ų63.523%0.2338%0.379CS..Hα-helixtrans-69.2-37.2177-70178.7178.6163.40112.7M119 D142 T176 A182M119-K178 HydrophobicContact CE-CB 4.46Å; M119-K178 WeakPolarHBondContact CE-O 3.46Å; D142-K178 VanDerWaalsContact CB-NZ 3.31Å; D142-K178 IonicContact OD1-NZ 3.58Å; D142-K178 WeakPolarHBondContact OD2-CE 3.44Å; D142-K178 IonicContact OD2-NZ 2.83Å; D142-K178 PolarHBondContact OD2-NZ 2.84Å; T176-K178 PolarHBondContact O-N 3.02Å; K178-A182 WeakPolarHBondContact O-CB 3.46Å; K178-A182 PolarHBondContact O-N 3.14Å
179Q95Very high92.7Very high125 Ų12564 Ų6458%0.58438%0.377SS*.Hα-helixtrans-69.7-42.2175.9-64.8126.55.900110T176 A182 S183T176-Q179 VanDerWaalsContact CA-OE1 3.23Å; T176-Q179 WeakPolarHBondContact O-CA 3.48Å; T176-Q179 WeakPolarHBondContact O-CB 3.5Å; T176-Q179 PolarHBondContact O-N 2.78Å; T176-Q179 PolarHBondContact O-OE1 2.95Å; Q179-A182 PolarHBondContact O-N 2.98Å; Q179-S183 PolarHBondContact O-N 2.52Å; Q179-S183 PolarHBondContact O-OG 2.85Å
180D93.6Very high92.9Very high78 Ų7862 Ų6242%0.41736%0.356SS..Hα-helixtrans-65.1-41.3177.3-57.2-34.9000111.4T176 S183 T184T176-D180 PolarHBondContact O-N 3.49Å; T176-D180 VanDerWaalsContact O-N 3.12Å; T176-D180 PolarHBondContact OG1-OD2 2.96Å; D180-S183 PolarHBondContact O-N 2.86Å; D180-S183 PolarHBondContact O-OG 3.19Å; D180-T184 WeakPolarHBondContact O-CB 3.36Å; D180-T184 PolarHBondContact O-N 2.85Å; D180-T184 PolarHBondContact O-OG1 2.99Å
181L94.4Very high93Very high9 Ų960 Ų605%0.04735%0.349CS..Hα-helixtrans-66.1-37.1174.6-176.362.4000112.2V10 P12 M119 W177 C187 K189V10-L181 HydrophobicContact CG1-CD2 4.36Å; P12-L181 HydrophobicContact CB-CD1 4.36Å; P12-L181 HydrophobicContact CB-CD2 4.08Å; M119-L181 HydrophobicContact CE-CB 4.2Å; M119-L181 HydrophobicContact CE-CD2 4.07Å; M119-L181 HydrophobicContact CE-CG 4.17Å; M119-L181 HydrophobicContact SD-CD2 4.17Å; M119-L181 HydrophobicContact SD-CG 4.24Å; W177-L181 HydrophobicContact CE3-CB 4.48Å; W177-L181 HydrophobicContact CE3-CD2 4.14Å; W177-L181 HydrophobicContact CZ3-CD2 3.65Å; W177-L181 WeakPolarHBondContact O-CB 3.35Å; W177-L181 PolarHBondContact O-N 3.01Å; L181-C187 HydrophobicContact CD1-CB 3.79Å; L181-C187 WeakPolarHBondContact CD1-SG 3.41Å; L181-K189 HydrophobicContact CD1-CB 4.09Å; L181-K189 HydrophobicContact CD2-CB 3.91Å; L181-K189 HydrophobicContact CG-CB 3.92Å; L181-K189 PolarHBondContact O-NZ 2.91Å
182A93.1Very high93.1Very high53 Ų5359.2 Ų59.244%0.43834%0.341SS..Hα-helixtrans-65.8-40.2177.100000111.8M119 K178 Q179 K189M119-A182 HydrophobicContact CE-CB 4.19Å; M119-A182 HydrophobicContact CG-CB 4.44Å; K178-A182 WeakPolarHBondContact O-CB 3.46Å; K178-A182 PolarHBondContact O-N 3.14Å; Q179-A182 PolarHBondContact O-N 2.98Å; A182-K189 PolarHBondContact O-NZ 2.92Å
183S90.4Very high93.2Very high93 Ų9356.7 Ų56.765%0.6532%0.324SS*.Hα-helixtrans-80.3-22-177.864.60000114Q179 D180Q179-S183 PolarHBondContact O-N 2.52Å; Q179-S183 PolarHBondContact O-OG 2.85Å; D180-S183 PolarHBondContact O-N 2.86Å; D180-S183 PolarHBondContact O-OG 3.19Å
184T85.8Confident93.2Very high58 Ų5856.6 Ų56.636%0.35632%0.324SS..  trans-82.6129.3179.1-54.30000111.5D180 C187 K189D180-T184 WeakPolarHBondContact O-CB 3.36Å; D180-T184 PolarHBondContact O-N 2.85Å; D180-T184 PolarHBondContact O-OG1 2.99Å; T184-C187 HydrophobicContact CG2-CB 3.82Å; T184-K189 PolarHBondContact O-NZ 3.35Å
185T79.3Confident93.3Very high130 Ų13051.7 Ų51.780%0.79830%0.301SS*.SBendtrans-81.2-35.4178.1-31.50000112.4
186D79.6Confident93.5Very high155 Ų15546 Ų4683%0.82926%0.264SS*.SBendtrans-89-11.4-169.7-57.1-34.5000114
187C83.9Confident93.6Very high34 Ų3443.2 Ų43.223%0.2325%0.247CC..SBendtrans-91.9121.5178.5-166.40000109.6L181 T184L181-C187 HydrophobicContact CD1-CB 3.79Å; L181-C187 WeakPolarHBondContact CD1-SG 3.41Å; T184-C187 HydrophobicContact CG2-CB 3.82Å
188P92.9Very high93.6Very high36 Ų3642.6 Ų42.623%0.23424%0.244CC..  trans-68.6145.3-178.230.8-36000110.6P12 C13P12-P188 CarbonylContact C-O 2.92Å; P12-P188 VanDerWaalsContact C-O 3.28Å; C13-P188 PolarHBondContact N-O 3.43Å; C13-P188 CarbonylContact O-C 3.59Å
189K95.3Very high93.6Very high55 Ų5543.1 Ų43.124%0.23925%0.246CC..  trans-142144.6-175.461.3-165.7128.9-154.90111.3C13 M119 L181 A182 T184C13-K189 CarbonylContact O-C 3.57Å; C13-K189 WeakPolarHBondContact O-CA 3.21Å; C13-K189 PolarHBondContact O-N 3.16Å; M119-K189 HydrophobicContact CG-CD 4.06Å; M119-K189 HydrophobicContact SD-CB 3.83Å; M119-K189 HydrophobicContact SD-CD 3.56Å; M119-K189 VanDerWaalsContact SD-CD 3.56Å; M119-K189 HydrophobicContact SD-CG 4.04Å; L181-K189 HydrophobicContact CD1-CB 4.09Å; L181-K189 HydrophobicContact CD2-CB 3.91Å; L181-K189 HydrophobicContact CG-CB 3.92Å; L181-K189 PolarHBondContact O-NZ 2.91Å; A182-K189 PolarHBondContact O-NZ 2.92Å; T184-K189 PolarHBondContact O-NZ 3.35Å
190M98.2Very high93.4Very high0 Ų037.6 Ų37.60%022%0.22CC..EExtended strand (participates in β ladder)trans-151.7161.5175.164123.5-55.900111.1V10 L11 C13 I15 Y18 K116 D118 A192V10-M190 WeakPolarHBondContact CA-O 3.38Å; L11-M190 HydrophobicContact CB-CG 4.2Å; L11-M190 HydrophobicContact CB-SD 4.47Å; L11-M190 HydrophobicContact CD1-CE 4.28Å; L11-M190 HydrophobicContact CD1-SD 4.03Å; L11-M190 PolarHBondContact N-O 2.55Å; L11-M190 PolarHBondContact O-N 3.37Å; C13-M190 WeakPolarHBondContact O-CG 3.42Å; C13-M190 PolarHBondContact O-N 2.63Å; I15-M190 HydrophobicContact CG2-CB 3.78Å; Y18-M190 VanDerWaalsContact CB-SD 3.54Å; Y18-M190 HydrophobicContact CD1-SD 4.22Å; Y18-M190 HydrophobicContact CD2-SD 3.62Å; Y18-M190 HydrophobicContact CE2-SD 4.37Å; Y18-M190 HydrophobicContact CG-SD 3.51Å; Y18-M190 VanDerWaalsContact CG-SD 3.51Å; K116-M190 CarbonylContact O-C 3.34Å; K116-M190 VanDerWaalsContact O-CA 3.23Å; K116-M190 WeakPolarHBondContact O-CA 3.17Å; K116-M190 WeakPolarHBondContact O-CB 3.28Å; D118-M190 CarbonylContact O-C 3.55Å; D118-M190 WeakPolarHBondContact O-CA 3.41Å; M190-A192 HydrophobicContact CE-CB 3.9Å
191C98.8Very high93.3Very high0 Ų040.8 Ų40.80%023%0.231CC..EExtended strand (participates in β ladder)trans-127.2130.9169-1730000111.9V9 V10 K116 D118 G120 Y193V9-C191 CarbonylContact O-C 3.2Å; V9-C191 WeakPolarHBondContact O-CA 3.36Å; V10-C191 HydrophobicContact CG2-CB 4.29Å; K116-C191 PolarHBondContact N-O 3.36Å; K116-C191 PolarHBondContact O-N 2.83Å; D118-C191 PolarHBondContact O-N 3.04Å; D118-C191 VanDerWaalsContact OD1-CB 3.31Å; D118-C191 WeakPolarHBondContact OD1-CB 3.16Å; G120-C191 WeakPolarHBondContact CA-SG 3.48Å; C191-Y193 HydrophobicContact CB-CD2 4.27Å; C191-Y193 HydrophobicContact CB-CE2 3.73Å
192A98.8Very high93Very high0 Ų044.2 Ų44.20%024%0.243CC..EExtended strand (participates in β ladder)trans-92.5112171.900000108.1R8 V9 T113 M190 K194R8-A192 WeakPolarHBondContact CA-O 3.25Å; V9-A192 HydrophobicContact CB-CB 4.33Å; V9-A192 PolarHBondContact N-O 3.35Å; V9-A192 PolarHBondContact O-N 3.41Å; T113-A192 HydrophobicContact CG2-CB 4.45Å; M190-A192 HydrophobicContact CE-CB 3.9Å; A192-K194 HydrophobicContact CB-CG 4.34Å; A192-K194 PolarHBondContact O-N 3.33Å
193Y98.8Very high92.6Very high0 Ų053.5 Ų53.50%027%0.267CS..EExtended strand (participates in β ladder)trans-92.596.5175.3-67.1-99.1000108.5R8 T113 W114 K116 D118 G120 T121 Q122 V125 H126 C191R8-Y193 HydrophobicContact CG-CD1 3.95Å; R8-Y193 HydrophobicContact CG-CE1 4.17Å; T113-Y193 VanDerWaalsContact CA-O 3.27Å; T113-Y193 WeakPolarHBondContact CA-O 3.36Å; W114-Y193 PolarHBondContact N-O 3.49Å; W114-Y193 VanDerWaalsContact N-O 3.1Å; W114-Y193 PolarHBondContact O-N 3.05Å; K116-Y193 HydrophobicContact CB-CD2 4.35Å; K116-Y193 HydrophobicContact CB-CE2 3.94Å; K116-Y193 HydrophobicContact CG-CD2 4.05Å; K116-Y193 HydrophobicContact CG-CE2 3.96Å; D118-Y193 WeakPolarHBondContact OD1-CE2 3.3Å; D118-Y193 PolarHBondContact OD1-OH 3.24Å; D118-Y193 VanDerWaalsContact OD1-OH 3.12Å; D118-Y193 PolarHBondContact OD2-OH 2.83Å; D118-Y193 VanDerWaalsContact OD2-OH 3.13Å; G120-Y193 WeakPolarHBondContact CA-OH 3.48Å; T121-Y193 PolarHBondContact N-OH 3Å; T121-Y193 VanDerWaalsContact N-OH 3.12Å; Q122-Y193 HydrophobicContact CB-CE1 4.39Å; Q122-Y193 WeakPolarHBondContact CB-OH 3.16Å; Q122-Y193 PolarHBondContact N-OH 2.84Å; Q122-Y193 VanDerWaalsContact O-CE1 3.3Å; Q122-Y193 WeakPolarHBondContact O-CE1 3.46Å; V125-Y193 HydrophobicContact CG1-CD1 4.05Å; V125-Y193 HydrophobicContact CG1-CE1 3.96Å; V125-Y193 HydrophobicContact CG1-CE2 4.46Å; V125-Y193 HydrophobicContact CG1-CG 4.32Å; V125-Y193 HydrophobicContact CG2-CD1 3.78Å; V125-Y193 HydrophobicContact CG2-CD2 4.39Å; V125-Y193 HydrophobicContact CG2-CG 3.69Å; H126-Y193 PolarHBondContact CE1-O 3.5Å; C191-Y193 HydrophobicContact CB-CD2 4.27Å; C191-Y193 HydrophobicContact CB-CE2 3.73Å
194K98.8Very high92.5Very high9 Ų952.4 Ų52.44%0.03927%0.27CS..EExtended strand (participates in β ladder)trans-100.296.4-177.2-53.8-166.3-177.8-54.80110.3Q6 N7 Y18 I111 E112 T113 A192 V196 F221 H225Q6-K194 CarbonylContact C-O 3.51Å; Q6-K194 WeakPolarHBondContact CA-O 3.49Å; N7-K194 HydrophobicContact CB-CB 4.35Å; N7-K194 PolarHBondContact N-O 3.12Å; N7-K194 PolarHBondContact O-N 3.13Å; Y18-K194 PolarHBondContact OH-NZ 2.87Å; I111-K194 HydrophobicContact CG2-CB 4.44Å; E112-K194 CarbonylContact O-C 3.46Å; T113-K194 HydrophobicContact CG2-CG 3.86Å; A192-K194 HydrophobicContact CB-CG 4.34Å; A192-K194 PolarHBondContact O-N 3.33Å; K194-V196 PolarHBondContact O-N 2.81Å; K194-F221 HydrophobicContact CB-CE2 3.97Å; K194-F221 HydrophobicContact CB-CZ 4.27Å; K194-F221 HydrophobicContact CD-CD1 3.91Å; K194-F221 HydrophobicContact CD-CD2 4.05Å; K194-F221 HydrophobicContact CD-CE1 3.82Å; K194-F221 HydrophobicContact CD-CE2 3.94Å; K194-F221 HydrophobicContact CD-CG 4.05Å; K194-F221 HydrophobicContact CD-CZ 3.84Å; K194-H225 WeakPolarHBondContact CE-CE1 3.35Å
195L98.8Very high92.6Very high3 Ų351.7 Ų51.72%0.01626%0.264CS..EExtended strand (participates in β ladder)trans-80.7109.7173.9-178.667.5000109.7L4 Q6 I111 E112 H126 V128 V136L4-L195 HydrophobicContact CD2-CD1 4.36Å; Q6-L195 HydrophobicContact CB-CD1 4.08Å; I111-L195 WeakPolarHBondContact CA-O 3.15Å; E112-L195 PolarHBondContact N-O 3.09Å; E112-L195 PolarHBondContact O-N 3.37Å; H126-L195 HydrophobicContact CB-CD2 3.88Å; V128-L195 HydrophobicContact CG2-CD2 3.57Å; V136-L195 HydrophobicContact CG1-CD1 4Å
196V98.7Very high93.1Very high0 Ų048.4 Ų48.40%024%0.24CC..EExtended strand (participates in β ladder)trans-98124.4177.6-174.70000108.6L4 K5 I109 K110 I111 K194 V198 H214 E217 F221L4-V196 VanDerWaalsContact CA-O 3.3Å; L4-V196 WeakPolarHBondContact CA-O 3.49Å; K5-V196 PolarHBondContact N-O 3.06Å; K5-V196 PolarHBondContact O-N 2.65Å; I109-V196 HydrophobicContact CG2-CG1 4.14Å; K110-V196 CarbonylContact O-C 3.15Å; K110-V196 WeakPolarHBondContact O-CA 3.38Å; I111-V196 HydrophobicContact CG1-CG2 4.4Å; K194-V196 PolarHBondContact O-N 2.81Å; V196-V198 HydrophobicContact CG1-CG2 3.94Å; V196-H214 PolarHBondContact O-CE1 2.95Å; V196-E217 HydrophobicContact CG1-CG 4.2Å; V196-F221 HydrophobicContact CG2-CE2 3.71Å; V196-F221 HydrophobicContact CG2-CZ 4Å
197T98.2Very high93.7Very high4 Ų445.6 Ų45.63%0.02523%0.228CC..EExtended strand (participates in β ladder)trans-113.6120.4170.3-52.30000108.4L2 L4 F108 I109 K110L2-T197 HydrophobicContact CB-CG2 4.14Å; L2-T197 HydrophobicContact CD1-CG2 4.2Å; L2-T197 HydrophobicContact CD2-CG2 4.4Å; L2-T197 HydrophobicContact CG-CG2 4.49Å; L4-T197 HydrophobicContact CD1-CG2 3.85Å; L4-T197 HydrophobicContact CG-CG2 4.02Å; F108-T197 HydrophobicContact CE2-CG2 3.78Å; F108-T197 HydrophobicContact CZ-CG2 4.22Å; I109-T197 WeakPolarHBondContact CA-O 3.47Å; K110-T197 PolarHBondContact N-O 3.45Å; K110-T197 PolarHBondContact O-N 3.47Å
198V97Very high94Very high0 Ų050 Ų500%024%0.244CC..EExtended strand (participates in β ladder)trans-110.9133.9175.2-1730000109C3 I109 V196 E210 I213 H214C3-V198 PolarHBondContact N-O 3.18Å; C3-V198 VanDerWaalsContact N-O 3.17Å; C3-V198 PolarHBondContact O-N 2.81Å; I109-V198 HydrophobicContact CG2-CG2 4.46Å; V196-V198 HydrophobicContact CG1-CG2 3.94Å; V198-E210 HydrophobicContact CG1-CB 4.35Å; V198-E210 HydrophobicContact CG1-CG 4.02Å; V198-I213 HydrophobicContact CG1-CB 4.14Å; V198-I213 HydrophobicContact CG1-CD1 3.65Å; V198-I213 HydrophobicContact CG1-CG2 4.02Å; V198-I213 HydrophobicContact CG2-CB 4.26Å; V198-I213 HydrophobicContact CG2-CG2 3.6Å; V198-H214 WeakPolarHBondContact CG2-NE2 3.44Å
199K95.3Very high93.9Very high63 Ų6348.7 Ų48.727%0.27424%0.235SC..EExtended strand (participates in β ladder)trans-122.1123.9165.9-177.9-178.8-179.8-168.70107.9L2 D105 F107 F108L2-K199 HydrophobicContact CD2-CB 3.75Å; L2-K199 HydrophobicContact CD2-CD 4.14Å; L2-K199 HydrophobicContact CD2-CG 4.02Å; D105-K199 WeakPolarHBondContact O-CE 3.31Å; D105-K199 PolarHBondContact O-NZ 3.33Å; F107-K199 VanDerWaalsContact CA-O 3.27Å; F107-K199 WeakPolarHBondContact CA-O 3.24Å; F108-K199 HydrophobicContact CD1-CB 3.63Å; F108-K199 HydrophobicContact CD1-CD 3.62Å; F108-K199 HydrophobicContact CD1-CG 4.24Å; F108-K199 HydrophobicContact CD2-CB 4.32Å; F108-K199 HydrophobicContact CE1-CB 3.46Å; F108-K199 VanDerWaalsContact CE1-CB 3.46Å; F108-K199 HydrophobicContact CE1-CD 3.26Å; F108-K199 HydrophobicContact CE1-CG 4Å; F108-K199 HydrophobicContact CE2-CB 4.15Å; F108-K199 HydrophobicContact CG-CB 4.07Å; F108-K199 HydrophobicContact CZ-CB 3.72Å; F108-K199 HydrophobicContact CZ-CD 4.16Å; F108-K199 PolarHBondContact N-O 2.99Å; F108-K199 PolarHBondContact O-N 3.3Å
200F92.6Very high93.8Very high9 Ų946.7 Ų46.74%0.03923%0.226CC..EExtended strand (participates in β ladder)trans-141.1101.7168.4179-94.2000109.8I75 M103 S106 F107 W202 L205 Q206 V209 E210I75-F200 HydrophobicContact CD1-CZ 4.36Å; M103-F200 HydrophobicContact CE-CE2 4.49Å; M103-F200 HydrophobicContact SD-CD2 3.85Å; M103-F200 HydrophobicContact SD-CE2 3.46Å; M103-F200 WeakPolarHBondContact SD-CE2 3.21Å; S106-F200 CarbonylContact O-C 3.59Å; S106-F200 VanDerWaalsContact O-CA 3.32Å; S106-F200 WeakPolarHBondContact O-CA 3.42Å; F107-F200 AromaticContact CD2-CD2 3.94Å; F107-F200 HydrophobicContact CD2-CD2 3.94Å; F200-W202 HydrophobicContact CD1-CB 4.04Å; F200-W202 HydrophobicContact CE1-CB 3.31Å; F200-W202 HydrophobicContact CE1-CG 4.22Å; F200-W202 HydrophobicContact CE2-CE3 4.16Å; F200-W202 HydrophobicContact CZ-CB 3.65Å; F200-W202 HydrophobicContact CZ-CD2 4.16Å; F200-W202 AromaticContact CZ-CE3 3.74Å; F200-W202 HydrophobicContact CZ-CE3 3.74Å; F200-W202 HydrophobicContact CZ-CG 4.18Å; F200-W202 PolarHBondContact O-N 2.88Å; F200-L205 HydrophobicContact CE1-CB 3.97Å; F200-Q206 WeakPolarHBondContact O-CB 3.08Å; F200-Q206 WeakPolarHBondContact O-CG 3.34Å; F200-V209 HydrophobicContact CB-CG1 4.19Å; F200-V209 HydrophobicContact CD1-CB 3.49Å; F200-V209 VanDerWaalsContact CD1-CB 3.49Å; F200-V209 HydrophobicContact CD1-CG1 3.67Å; F200-V209 HydrophobicContact CD1-CG2 3.96Å; F200-V209 HydrophobicContact CD2-CB 4.49Å; F200-V209 HydrophobicContact CD2-CG1 3.75Å; F200-V209 HydrophobicContact CE1-CB 3.63Å; F200-V209 HydrophobicContact CE1-CG1 3.88Å; F200-V209 HydrophobicContact CE1-CG2 3.52Å; F200-V209 HydrophobicContact CE2-CG1 3.94Å; F200-V209 HydrophobicContact CG-CB 3.96Å; F200-V209 HydrophobicContact CG-CG1 3.61Å; F200-V209 HydrophobicContact CZ-CB 4.2Å; F200-V209 HydrophobicContact CZ-CG1 4.02Å; F200-V209 HydrophobicContact CZ-CG2 3.92Å; F200-E210 HydrophobicContact CB-CG 4Å; F200-E210 PolarHBondContact N-OE1 3.41Å; F200-E210 VanDerWaalsContact N-OE1 3.13Å
201K91.6Very high93.6Very high145 Ų14549.7 Ų49.763%0.6324%0.242SC*.  trans-97.785.4-175.7-170.1-177.1178.6-176.70110.5S106S106-K201 PolarHBondContact O-N 2.8Å
202W86.4Confident93.3Very high82 Ų8251.2 Ų51.231%0.31125%0.249SC..  trans-133.9128.7173.3-157.4-57.1000110.4I75 Y102 F200 G204 L205 Q206I75-W202 HydrophobicContact CB-CH2 4.22Å; I75-W202 HydrophobicContact CB-CZ2 4.14Å; I75-W202 VanDerWaalsContact O-CH2 3.3Å; I75-W202 WeakPolarHBondContact O-CH2 3.4Å; Y102-W202 HydrophobicContact CE1-CH2 4.03Å; Y102-W202 HydrophobicContact CE1-CZ3 4.11Å; F200-W202 HydrophobicContact CD1-CB 4.04Å; F200-W202 HydrophobicContact CE1-CB 3.31Å; F200-W202 HydrophobicContact CE1-CG 4.22Å; F200-W202 HydrophobicContact CE2-CE3 4.16Å; F200-W202 HydrophobicContact CZ-CB 3.65Å; F200-W202 HydrophobicContact CZ-CD2 4.16Å; F200-W202 AromaticContact CZ-CE3 3.74Å; F200-W202 HydrophobicContact CZ-CE3 3.74Å; F200-W202 HydrophobicContact CZ-CG 4.18Å; F200-W202 PolarHBondContact O-N 2.88Å; W202-G204 PolarHBondContact O-N 3.49Å; W202-L205 HydrophobicContact CB-CB 4.37Å; W202-L205 PolarHBondContact O-N 2.92Å; W202-L205 VanDerWaalsContact O-N 3.16Å; W202-Q206 PolarHBondContact O-N 3.3Å; W202-Q206 VanDerWaalsContact O-N 3.14Å
203W86.5Confident93.1Very high248 Ų24852.1 Ų52.194%0.93925%0.254SS*.THydrogen-bonded Turntrans-59.9126.1-177.3-174.683.7000111.2L205W203-L205 VanDerWaalsContact C-N 3.27Å; W203-L205 PolarHBondContact O-N 3.38Å
204G87.3Confident93Very high70 Ų7052.3 Ų52.372%0.72226%0.255SS*.THydrogen-bonded Turntrans80.5-9.8-179.900000116.1W202W202-G204 PolarHBondContact O-N 3.49Å
205L88.3Confident92.8Very high43 Ų4357.4 Ų57.423%0.22528%0.279CS..THydrogen-bonded Turntrans-122.5-10.9-175.4-64.8178000114.6I75 F200 W202 W203 T207 K208 V209I75-L205 HydrophobicContact CD1-CD1 3.59Å; I75-L205 HydrophobicContact CG2-CD1 4.06Å; F200-L205 HydrophobicContact CE1-CB 3.97Å; W202-L205 HydrophobicContact CB-CB 4.37Å; W202-L205 PolarHBondContact O-N 2.92Å; W202-L205 VanDerWaalsContact O-N 3.16Å; W203-L205 VanDerWaalsContact C-N 3.27Å; W203-L205 PolarHBondContact O-N 3.38Å; L205-T207 PolarHBondContact O-N 3Å; L205-K208 PolarHBondContact O-N 2.93Å; L205-V209 HydrophobicContact CB-CG2 4.24Å; L205-V209 WeakPolarHBondContact O-CG2 3.42Å; L205-V209 PolarHBondContact O-N 3.31Å
206Q90.6Very high92.6Very high60 Ų6058.7 Ų58.728%0.2828%0.284SS..Hα-helixtrans-44.3-67.5-175.8175.3157.8-1.700113.7F200 W202 K208 V209 E210F200-Q206 WeakPolarHBondContact O-CB 3.08Å; F200-Q206 WeakPolarHBondContact O-CG 3.34Å; W202-Q206 PolarHBondContact O-N 3.3Å; W202-Q206 VanDerWaalsContact O-N 3.14Å; Q206-K208 VanDerWaalsContact C-N 3.31Å; Q206-K208 PolarHBondContact O-N 3.33Å; Q206-V209 PolarHBondContact O-N 2.88Å; Q206-E210 HydrophobicContact CG-CG 4.37Å; Q206-E210 PolarHBondContact NE2-OE1 2.79Å; Q206-E210 WeakPolarHBondContact O-CB 3.42Å; Q206-E210 WeakPolarHBondContact O-CG 3.46Å; Q206-E210 PolarHBondContact O-N 2.59Å
207T91.4Very high92.6Very high97 Ų9759.7 Ų59.760%0.59529%0.289SS*.Hα-helixtrans-62.3-37.8-173.9-53.80000112.7L205 N211L205-T207 PolarHBondContact O-N 3Å; T207-N211 WeakPolarHBondContact O-CB 3.34Å; T207-N211 PolarHBondContact O-N 2.95Å; T207-N211 PolarHBondContact O-ND2 2.89Å
208K90.4Very high92.6Very high126 Ų12663 Ų6355%0.54830%0.303SS..Hα-helixtrans-63.6-48179.7-175.7177.5178.7-179.60110.9L205 Q206 F212L205-K208 PolarHBondContact O-N 2.93Å; Q206-K208 VanDerWaalsContact C-N 3.31Å; Q206-K208 PolarHBondContact O-N 3.33Å; K208-F212 WeakPolarHBondContact O-CB 3.4Å; K208-F212 PolarHBondContact O-N 2.81Å
209V90.3Very high92.6Very high9 Ų964.5 Ų64.56%0.05531%0.309CS..Hα-helixtrans-72.5-40.4-178.2176.40000111.5F71 F200 L205 Q206 N211 F212 I213F71-V209 HydrophobicContact CE2-CG2 4.13Å; F200-V209 HydrophobicContact CB-CG1 4.19Å; F200-V209 HydrophobicContact CD1-CB 3.49Å; F200-V209 VanDerWaalsContact CD1-CB 3.49Å; F200-V209 HydrophobicContact CD1-CG1 3.67Å; F200-V209 HydrophobicContact CD1-CG2 3.96Å; F200-V209 HydrophobicContact CD2-CB 4.49Å; F200-V209 HydrophobicContact CD2-CG1 3.75Å; F200-V209 HydrophobicContact CE1-CB 3.63Å; F200-V209 HydrophobicContact CE1-CG1 3.88Å; F200-V209 HydrophobicContact CE1-CG2 3.52Å; F200-V209 HydrophobicContact CE2-CG1 3.94Å; F200-V209 HydrophobicContact CG-CB 3.96Å; F200-V209 HydrophobicContact CG-CG1 3.61Å; F200-V209 HydrophobicContact CZ-CB 4.2Å; F200-V209 HydrophobicContact CZ-CG1 4.02Å; F200-V209 HydrophobicContact CZ-CG2 3.92Å; L205-V209 HydrophobicContact CB-CG2 4.24Å; L205-V209 WeakPolarHBondContact O-CG2 3.42Å; L205-V209 PolarHBondContact O-N 3.31Å; Q206-V209 PolarHBondContact O-N 2.88Å; V209-N211 VanDerWaalsContact C-N 3.33Å; V209-N211 PolarHBondContact O-N 2.85Å; V209-F212 PolarHBondContact O-N 3.08Å; V209-I213 HydrophobicContact CG1-CD1 3.76Å; V209-I213 HydrophobicContact CG1-CG1 4.31Å; V209-I213 VanDerWaalsContact O-CG1 3.3Å; V209-I213 WeakPolarHBondContact O-CG1 3.48Å; V209-I213 PolarHBondContact O-N 2.89Å
210E93.8Very high92.6Very high12 Ų1265.9 Ų65.96%0.05632%0.318CS..Hα-helixtrans-59.7-44.3175.9-72.1177.1165.100111.4C3 V198 F200 Q206 I213 H214C3-E210 HydrophobicContact CB-CB 4.08Å; C3-E210 HydrophobicContact CB-CG 4.4Å; V198-E210 HydrophobicContact CG1-CB 4.35Å; V198-E210 HydrophobicContact CG1-CG 4.02Å; F200-E210 HydrophobicContact CB-CG 4Å; F200-E210 PolarHBondContact N-OE1 3.41Å; F200-E210 VanDerWaalsContact N-OE1 3.13Å; Q206-E210 HydrophobicContact CG-CG 4.37Å; Q206-E210 PolarHBondContact NE2-OE1 2.79Å; Q206-E210 WeakPolarHBondContact O-CB 3.42Å; Q206-E210 WeakPolarHBondContact O-CG 3.46Å; Q206-E210 PolarHBondContact O-N 2.59Å; E210-I213 PolarHBondContact O-N 2.79Å; E210-H214 PolarHBondContact O-CD2 3.15Å; E210-H214 PolarHBondContact O-N 2.87Å; E210-H214 VanDerWaalsContact O-N 3.15Å
211N93.8Very high92.9Very high63 Ų6366.2 Ų66.234%0.33732%0.32SS..Hα-helixtrans-65.5-45176-76.3-27.2000112.4T207 V209 I213 H214 E215T207-N211 WeakPolarHBondContact O-CB 3.34Å; T207-N211 PolarHBondContact O-N 2.95Å; T207-N211 PolarHBondContact O-ND2 2.89Å; V209-N211 VanDerWaalsContact C-N 3.33Å; V209-N211 PolarHBondContact O-N 2.85Å; N211-I213 VanDerWaalsContact C-N 3.33Å; N211-I213 PolarHBondContact O-N 2.86Å; N211-H214 WeakPolarHBondContact O-CB 3.36Å; N211-H214 PolarHBondContact O-N 3.45Å; N211-E215 WeakPolarHBondContact O-CG 3.43Å; N211-E215 PolarHBondContact O-N 3.21Å
212F92.6Very high93.2Very high33 Ų3359.4 Ų59.415%0.14529%0.291CS..Hα-helixtrans-57.1-45.8176.7171-99.4000111.8P69 F71 K208 V209 H214 E215 Q216 A268P69-F212 HydrophobicContact CG-CE1 3.76Å; P69-F212 HydrophobicContact CG-CE2 3.6Å; P69-F212 HydrophobicContact CG-CZ 3.15Å; F71-F212 HydrophobicContact CZ-CD1 4.34Å; F71-F212 HydrophobicContact CZ-CD2 4.46Å; F71-F212 HydrophobicContact CZ-CG 4.2Å; K208-F212 WeakPolarHBondContact O-CB 3.4Å; K208-F212 PolarHBondContact O-N 2.81Å; V209-F212 PolarHBondContact O-N 3.08Å; F212-H214 VanDerWaalsContact C-N 3.34Å; F212-H214 PolarHBondContact O-N 2.77Å; F212-E215 WeakPolarHBondContact O-CB 3.31Å; F212-E215 PolarHBondContact O-N 2.85Å; F212-E215 VanDerWaalsContact O-N 3.15Å; F212-Q216 HydrophobicContact CD1-CG 4.31Å; F212-Q216 HydrophobicContact CD2-CG 4.4Å; F212-Q216 HydrophobicContact CE1-CG 3.72Å; F212-Q216 HydrophobicContact CE2-CG 3.84Å; F212-Q216 VanDerWaalsContact CE2-NE2 3.27Å; F212-Q216 HydrophobicContact CZ-CG 3.42Å; F212-Q216 VanDerWaalsContact CZ-CG 3.42Å; F212-Q216 WeakPolarHBondContact O-CG 3.31Å; F212-Q216 PolarHBondContact O-N 2.77Å; F212-A268 HydrophobicContact CZ-CB 4.09Å
213I94Very high93.8Very high18 Ų1856.5 Ų56.59%0.09228%0.281CS..Hα-helixtrans-60-45.7177.1-70.2164.9000110.5F107 I109 V198 V209 E210 N211 E215 Q216 E217F107-I213 HydrophobicContact CE2-CD1 3.85Å; I109-I213 HydrophobicContact CD1-CD1 4.41Å; I109-I213 HydrophobicContact CD1-CG2 3.51Å; I109-I213 HydrophobicContact CG1-CG2 3.9Å; V198-I213 HydrophobicContact CG1-CB 4.14Å; V198-I213 HydrophobicContact CG1-CD1 3.65Å; V198-I213 HydrophobicContact CG1-CG2 4.02Å; V198-I213 HydrophobicContact CG2-CB 4.26Å; V198-I213 HydrophobicContact CG2-CG2 3.6Å; V209-I213 HydrophobicContact CG1-CD1 3.76Å; V209-I213 HydrophobicContact CG1-CG1 4.31Å; V209-I213 VanDerWaalsContact O-CG1 3.3Å; V209-I213 WeakPolarHBondContact O-CG1 3.48Å; V209-I213 PolarHBondContact O-N 2.89Å; E210-I213 PolarHBondContact O-N 2.79Å; N211-I213 VanDerWaalsContact C-N 3.33Å; N211-I213 PolarHBondContact O-N 2.86Å; I213-E215 VanDerWaalsContact C-N 3.26Å; I213-E215 PolarHBondContact O-N 2.82Å; I213-Q216 PolarHBondContact O-N 3.17Å; I213-Q216 VanDerWaalsContact O-N 3.17Å; I213-E217 HydrophobicContact CG2-CG 4.2Å; I213-E217 WeakPolarHBondContact O-CG 3.28Å; I213-E217 PolarHBondContact O-N 2.81Å
214H96.9Very high94.4Very high4 Ų446 Ų462%0.01924%0.242CC..Hα-helixtrans-60.3-35.2176.9-85.6-68.2000113.1C3 K5 V196 V198 E210 N211 F212 K218C3-H214 PolarHBondContact O-NE2 2.7Å; C3-H214 PolarHBondContact SG-CD2 3.31Å; C3-H214 PolarHBondContact SG-NE2 2.95Å; C3-H214 VanDerWaalsContact SG-NE2 3.4Å; K5-H214 HydrophobicContact CD-CB 3.95Å; V196-H214 PolarHBondContact O-CE1 2.95Å; V198-H214 WeakPolarHBondContact CG2-NE2 3.44Å; E210-H214 PolarHBondContact O-CD2 3.15Å; E210-H214 PolarHBondContact O-N 2.87Å; E210-H214 VanDerWaalsContact O-N 3.15Å; N211-H214 WeakPolarHBondContact O-CB 3.36Å; N211-H214 PolarHBondContact O-N 3.45Å; F212-H214 VanDerWaalsContact C-N 3.34Å; F212-H214 PolarHBondContact O-N 2.77Å; H214-K218 WeakPolarHBondContact O-CB 3.33Å; H214-K218 PolarHBondContact O-N 2.68Å
215E95.5Very high94.9Very high117 Ų11742.7 Ų42.755%0.54721%0.208SC..Hα-helixtrans-68.4-41.9174.7-71.5169.3-176.800111.8N211 F212 I213 K218 R219N211-E215 WeakPolarHBondContact O-CG 3.43Å; N211-E215 PolarHBondContact O-N 3.21Å; F212-E215 WeakPolarHBondContact O-CB 3.31Å; F212-E215 PolarHBondContact O-N 2.85Å; F212-E215 VanDerWaalsContact O-N 3.15Å; I213-E215 VanDerWaalsContact C-N 3.26Å; I213-E215 PolarHBondContact O-N 2.82Å; E215-K218 PolarHBondContact O-N 3.43Å; E215-R219 WeakPolarHBondContact O-CB 3.42Å; E215-R219 PolarHBondContact O-N 2.8Å
216Q94.7Very high95.4Very high29 Ų2940.9 Ų40.914%0.13620%0.198CC..Hα-helixtrans-66.4-42174.9-61.7-47.3-62.700112F212 I213 K218 R219 I220F212-Q216 HydrophobicContact CD1-CG 4.31Å; F212-Q216 HydrophobicContact CD2-CG 4.4Å; F212-Q216 HydrophobicContact CE1-CG 3.72Å; F212-Q216 HydrophobicContact CE2-CG 3.84Å; F212-Q216 VanDerWaalsContact CE2-NE2 3.27Å; F212-Q216 HydrophobicContact CZ-CG 3.42Å; F212-Q216 VanDerWaalsContact CZ-CG 3.42Å; F212-Q216 WeakPolarHBondContact O-CG 3.31Å; F212-Q216 PolarHBondContact O-N 2.77Å; I213-Q216 PolarHBondContact O-N 3.17Å; I213-Q216 VanDerWaalsContact O-N 3.17Å; Q216-K218 VanDerWaalsContact C-N 3.34Å; Q216-K218 PolarHBondContact O-N 2.92Å; Q216-R219 WeakPolarHBondContact O-CB 3.47Å; Q216-R219 PolarHBondContact O-N 3.17Å; Q216-I220 WeakPolarHBondContact O-CB 3.48Å; Q216-I220 VanDerWaalsContact O-CG1 3.25Å; Q216-I220 WeakPolarHBondContact O-CG1 3.28Å; Q216-I220 PolarHBondContact O-N 3.1Å
217E97.1Very high95.8Very high21 Ų2139.1 Ų39.110%0.09819%0.189CC..Hα-helixtrans-60.6-43.6175-72.3-67.2163.900111.2I111 V196 I213 R219 I220 F221I111-E217 WeakPolarHBondContact CD1-OE2 3.19Å; V196-E217 HydrophobicContact CG1-CG 4.2Å; I213-E217 HydrophobicContact CG2-CG 4.2Å; I213-E217 WeakPolarHBondContact O-CG 3.28Å; I213-E217 PolarHBondContact O-N 2.81Å; E217-R219 PolarHBondContact O-N 3.12Å; E217-I220 PolarHBondContact O-N 3.19Å; E217-F221 HydrophobicContact CB-CE2 4.3Å; E217-F221 HydrophobicContact CB-CZ 4.43Å; E217-F221 WeakPolarHBondContact O-CB 3.46Å; E217-F221 VanDerWaalsContact O-CD2 3.3Å; E217-F221 WeakPolarHBondContact O-CD2 3.42Å; E217-F221 WeakPolarHBondContact O-CG 3.47Å; E217-F221 PolarHBondContact O-N 3.21Å; E217-F221 WeakPolarHBondContact OE2-CZ 3.45Å
218K98.1Very high96.1Very high74 Ų7434.6 Ų34.632%0.32216%0.162SC..Hα-helixtrans-59.8-47.1173.4-174.7-172.1177.1-172.70111.1V139 I141 H214 E215 Q216 F221 T222V139-K218 HydrophobicContact CG1-CD 3.93Å; V139-K218 HydrophobicContact CG1-CG 4.36Å; I141-K218 HydrophobicContact CD1-CG 4.3Å; I141-K218 HydrophobicContact CG1-CG 4.48Å; H214-K218 WeakPolarHBondContact O-CB 3.33Å; H214-K218 PolarHBondContact O-N 2.68Å; E215-K218 PolarHBondContact O-N 3.43Å; Q216-K218 VanDerWaalsContact C-N 3.34Å; Q216-K218 PolarHBondContact O-N 2.92Å; K218-F221 PolarHBondContact O-N 3.17Å; K218-T222 PolarHBondContact O-N 2.96Å; K218-T222 PolarHBondContact O-OG1 2.83Å
219R97Very high96.5Very high31 Ų3128.9 Ų28.912%0.11714%0.137CC..Hα-helixtrans-57.9-47.9177.3-179.6-174.2-179-169.62.2111.5D153 E215 Q216 E217 T222 N223 T266 S267D153-R219 IonicContact OD1-CZ 3.08Å; D153-R219 IonicContact OD1-NE 2.81Å; D153-R219 PolarHBondContact OD1-NE 3.15Å; D153-R219 IonicContact OD1-NH2 2.87Å; D153-R219 PolarHBondContact OD1-NH2 2.93Å; D153-R219 IonicContact OD2-CZ 3.56Å; D153-R219 IonicContact OD2-NE 3.29Å; D153-R219 PolarHBondContact OD2-NE 2.87Å; D153-R219 IonicContact OD2-NH2 3.29Å; D153-R219 PolarHBondContact OD2-NH2 2.95Å; E215-R219 WeakPolarHBondContact O-CB 3.42Å; E215-R219 PolarHBondContact O-N 2.8Å; Q216-R219 WeakPolarHBondContact O-CB 3.47Å; Q216-R219 PolarHBondContact O-N 3.17Å; E217-R219 PolarHBondContact O-N 3.12Å; R219-T222 PolarHBondContact O-N 2.97Å; R219-N223 PolarHBondContact O-N 2.83Å; R219-N223 PolarHBondContact O-ND2 3.02Å; R219-T266 VanDerWaalsContact CZ-CG2 3.44Å; R219-T266 VanDerWaalsContact NH2-CG2 3.31Å; R219-S267 PolarHBondContact NH1-O 3.33Å
220I96.4Very high96.9Very high92 Ų9228.8 Ų28.847%0.47214%0.137SC..Hα-helixtrans-59.4-50.1177.2-70.2164.5000109.9Q216 E217 T222 N223 F224Q216-I220 WeakPolarHBondContact O-CB 3.48Å; Q216-I220 VanDerWaalsContact O-CG1 3.25Å; Q216-I220 WeakPolarHBondContact O-CG1 3.28Å; Q216-I220 PolarHBondContact O-N 3.1Å; E217-I220 PolarHBondContact O-N 3.19Å; I220-T222 PolarHBondContact O-N 2.97Å; I220-N223 PolarHBondContact O-N 3.32Å; I220-F224 WeakPolarHBondContact O-CB 3.27Å; I220-F224 PolarHBondContact O-N 3.41Å
221F98.5Very high97.2Very high17 Ų1729.1 Ų29.18%0.07514%0.138CC..Hα-helixtrans-62.1-41.6178.8-62.7-22000112.1N7 I111 I141 K194 V196 E217 K218 H225N7-F221 HydrophobicContact CB-CD2 3.86Å; N7-F221 HydrophobicContact CB-CE2 4.17Å; I111-F221 HydrophobicContact CD1-CE1 4.47Å; I111-F221 HydrophobicContact CD1-CZ 4.14Å; I111-F221 HydrophobicContact CG2-CZ 4.17Å; I141-F221 HydrophobicContact CD1-CB 3.47Å; I141-F221 VanDerWaalsContact CD1-CB 3.47Å; I141-F221 HydrophobicContact CD1-CD2 4.21Å; I141-F221 HydrophobicContact CD1-CG 4.37Å; K194-F221 HydrophobicContact CB-CE2 3.97Å; K194-F221 HydrophobicContact CB-CZ 4.27Å; K194-F221 HydrophobicContact CD-CD1 3.91Å; K194-F221 HydrophobicContact CD-CD2 4.05Å; K194-F221 HydrophobicContact CD-CE1 3.82Å; K194-F221 HydrophobicContact CD-CE2 3.94Å; K194-F221 HydrophobicContact CD-CG 4.05Å; K194-F221 HydrophobicContact CD-CZ 3.84Å; V196-F221 HydrophobicContact CG2-CE2 3.71Å; V196-F221 HydrophobicContact CG2-CZ 4Å; E217-F221 HydrophobicContact CB-CE2 4.3Å; E217-F221 HydrophobicContact CB-CZ 4.43Å; E217-F221 WeakPolarHBondContact O-CB 3.46Å; E217-F221 VanDerWaalsContact O-CD2 3.3Å; E217-F221 WeakPolarHBondContact O-CD2 3.42Å; E217-F221 WeakPolarHBondContact O-CG 3.47Å; E217-F221 PolarHBondContact O-N 3.21Å; E217-F221 WeakPolarHBondContact OE2-CZ 3.45Å; K218-F221 PolarHBondContact O-N 3.17Å; F221-H225 PolarHBondContact O-N 2.9Å; F221-H225 VanDerWaalsContact O-N 3.15Å; F221-H225 PolarHBondContact O-ND1 2.92Å
222T98.6Very high97.4Very high2 Ų226.2 Ų26.21%0.01212%0.122CC..Hα-helixtrans-59.7-54176.8-60.70000111.1Q148 V149 K218 R219 I220 R226Q148-T222 HydrophobicContact CB-CG2 4.33Å; V149-T222 HydrophobicContact CG2-CG2 3.93Å; K218-T222 PolarHBondContact O-N 2.96Å; K218-T222 PolarHBondContact O-OG1 2.83Å; R219-T222 PolarHBondContact O-N 2.97Å; I220-T222 PolarHBondContact O-N 2.97Å; T222-R226 VanDerWaalsContact O-CG 3.24Å; T222-R226 WeakPolarHBondContact O-CG 3.46Å; T222-R226 PolarHBondContact O-N 3.08Å; T222-R226 VanDerWaalsContact O-N 3.16Å
223N98.1Very high97.7Very high20 Ų2026.1 Ų26.111%0.10712%0.123CC..Hα-helixtrans-67.4-43.5-175.4-64.2-17.4000111.5D153 R219 I220 H225 R226 Q227D153-N223 VanDerWaalsContact CG-ND2 3.31Å; D153-N223 PolarHBondContact OD2-ND2 3.15Å; R219-N223 PolarHBondContact O-N 2.83Å; R219-N223 PolarHBondContact O-ND2 3.02Å; I220-N223 PolarHBondContact O-N 3.32Å; N223-H225 PolarHBondContact O-N 2.82Å; N223-R226 PolarHBondContact O-N 3.44Å; N223-Q227 WeakPolarHBondContact O-CG 3.42Å; N223-Q227 PolarHBondContact O-N 2.83Å
224F98.4Very high97.9Very high28 Ų2830.8 Ų30.812%0.12314%0.143CC..Hα-helixtrans-58.1-46.3178.7176.6-94.4000112.4Q22 V26 A29 I220 Q227 L228Q22-F224 HydrophobicContact CG-CE1 4.33Å; Q22-F224 HydrophobicContact CG-CZ 4.08Å; V26-F224 HydrophobicContact CG2-CE2 3.74Å; V26-F224 HydrophobicContact CG2-CZ 3.84Å; A29-F224 HydrophobicContact CB-CD2 4.49Å; I220-F224 WeakPolarHBondContact O-CB 3.27Å; I220-F224 PolarHBondContact O-N 3.41Å; F224-Q227 PolarHBondContact O-N 2.99Å; F224-L228 HydrophobicContact CE1-CD1 3.83Å; F224-L228 HydrophobicContact CZ-CD1 4.26Å; F224-L228 WeakPolarHBondContact O-CB 3.46Å; F224-L228 PolarHBondContact O-N 3.38Å
225H98.8Very high97.9Very high0 Ų030.7 Ų30.70%014%0.142CC..Hα-helixtrans-76.9-26-176.8-67.394.2000113.1V9 L11 Y18 I143 K194 F221 N223 F229V9-H225 HydrophobicContact CG1-CB 3.96Å; L11-H225 HydrophobicContact CD2-CB 4.12Å; Y18-H225 AromaticContact CE2-CD2 3.83Å; Y18-H225 AromaticContact CE2-NE2 3.85Å; Y18-H225 AromaticContact CZ-NE2 3.8Å; Y18-H225 PolarHBondContact OH-NE2 3.12Å; I143-H225 HydrophobicContact CG2-CB 3.62Å; K194-H225 WeakPolarHBondContact CE-CE1 3.35Å; F221-H225 PolarHBondContact O-N 2.9Å; F221-H225 VanDerWaalsContact O-N 3.15Å; F221-H225 PolarHBondContact O-ND1 2.92Å; N223-H225 PolarHBondContact O-N 2.82Å; H225-F229 PolarHBondContact O-N 3.26Å; H225-F229 VanDerWaalsContact O-N 3.14Å
226R98.8Very high98.1Very high6 Ų626.6 Ų26.62%0.02313%0.125CC..Hα-helixtrans-63.4-48.9168.7-75172.859.187.2-4.4111.2I143 E158 D159 P160 T222 N223 F229 C230I143-R226 HydrophobicContact CB-CG 3.95Å; I143-R226 HydrophobicContact CG2-CG 4.38Å; I143-R226 VanDerWaalsContact O-CG 3.28Å; I143-R226 WeakPolarHBondContact O-CG 3.47Å; I143-R226 PolarHBondContact O-NH1 2.81Å; E158-R226 PolarHBondContact O-NE 2.88Å; E158-R226 PolarHBondContact O-NH2 3.47Å; D159-R226 VanDerWaalsContact CA-NH2 3.27Å; D159-R226 IonicContact OD1-CZ 3.8Å; D159-R226 VanDerWaalsContact OD1-CZ 3.29Å; D159-R226 IonicContact OD1-NH1 2.81Å; D159-R226 PolarHBondContact OD1-NH1 3.05Å; D159-R226 IonicContact OD1-NH2 2.7Å; D159-R226 PolarHBondContact OD1-NH2 2.73Å; D159-R226 IonicContact OD2-NH2 2.75Å; P160-R226 HydrophobicContact CG-CB 4.06Å; P160-R226 HydrophobicContact CG-CG 3.98Å; T222-R226 VanDerWaalsContact O-CG 3.24Å; T222-R226 WeakPolarHBondContact O-CG 3.46Å; T222-R226 PolarHBondContact O-N 3.08Å; T222-R226 VanDerWaalsContact O-N 3.16Å; N223-R226 PolarHBondContact O-N 3.44Å; R226-F229 PolarHBondContact O-N 3.21Å; R226-C230 PolarHBondContact O-N 2.77Å; R226-C230 PolarHBondContact O-SG 2.96Å
227Q98.5Very high98.2Very high22 Ų2230.5 Ų30.510%0.10315%0.147CC..Hα-helixtrans-60.1-48174.8-74.3170.6-3.100111.7E158 N223 F224 F229 C230 W231E158-Q227 HydrophobicContact CB-CG 4.14Å; E158-Q227 VanDerWaalsContact CD-NE2 3.34Å; E158-Q227 HydrophobicContact CG-CG 3.94Å; E158-Q227 PolarHBondContact OE1-NE2 2.71Å; E158-Q227 WeakPolarHBondContact OE2-CG 3.3Å; E158-Q227 PolarHBondContact OE2-NE2 3.39Å; N223-Q227 WeakPolarHBondContact O-CG 3.42Å; N223-Q227 PolarHBondContact O-N 2.83Å; F224-Q227 PolarHBondContact O-N 2.99Å; Q227-F229 VanDerWaalsContact C-N 3.28Å; Q227-F229 PolarHBondContact O-N 3.44Å; Q227-C230 CarbonylContact O-C 3.55Å; Q227-C230 PolarHBondContact O-N 3.04Å; Q227-C230 VanDerWaalsContact O-N 3.13Å; Q227-W231 HydrophobicContact CB-CD2 4.17Å; Q227-W231 HydrophobicContact CB-CE3 4.03Å; Q227-W231 HydrophobicContact CB-CH2 3.69Å; Q227-W231 HydrophobicContact CB-CZ2 3.81Å; Q227-W231 HydrophobicContact CB-CZ3 3.8Å; Q227-W231 HydrophobicContact CG-CH2 3.94Å; Q227-W231 HydrophobicContact CG-CZ2 3.84Å; Q227-W231 WeakPolarHBondContact O-CB 3.48Å; Q227-W231 PolarHBondContact O-N 3.14Å
228L98.7Very high98.3Very high3 Ų331.6 Ų31.62%0.01615%0.153CC..Hα-helixtrans-52.6-46.6177.6-177.9155.2000111.7Y18 Q22 S25 F224 W231 I232 W235Y18-L228 HydrophobicContact CD2-CD1 4.08Å; Y18-L228 HydrophobicContact CE2-CD1 3.72Å; Q22-L228 HydrophobicContact CB-CD1 4.46Å; S25-L228 WeakPolarHBondContact OG-CA 3.45Å; F224-L228 HydrophobicContact CE1-CD1 3.83Å; F224-L228 HydrophobicContact CZ-CD1 4.26Å; F224-L228 WeakPolarHBondContact O-CB 3.46Å; F224-L228 PolarHBondContact O-N 3.38Å; L228-W231 PolarHBondContact O-N 3.34Å; L228-I232 PolarHBondContact O-N 2.94Å; L228-W235 HydrophobicContact CD2-CZ2 3.83Å; L228-W235 HydrophobicContact CG-CZ2 4.45Å; L228-W235 PolarHBondContact O-NE1 3.3Å
229F98.7Very high98.2Very high5 Ų531.8 Ų31.82%0.02216%0.157CC..Hα-helixtrans-67.1-46.6177.6179.7-101000112.3P12 I143 P160 F163 R170 L173 H225 R226 Q227 W231 I232P12-F229 HydrophobicContact CB-CE2 4.43Å; P12-F229 HydrophobicContact CG-CD2 3.57Å; P12-F229 HydrophobicContact CG-CE2 3.33Å; P12-F229 HydrophobicContact CG-CZ 4.26Å; I143-F229 HydrophobicContact CD1-CB 4.05Å; I143-F229 HydrophobicContact CD1-CG 4.27Å; P160-F229 HydrophobicContact CB-CD1 3.5Å; P160-F229 HydrophobicContact CB-CE1 3.9Å; P160-F229 HydrophobicContact CB-CG 4.41Å; P160-F229 HydrophobicContact CG-CB 4.39Å; P160-F229 HydrophobicContact CG-CD1 3.88Å; F163-F229 HydrophobicContact CD1-CD1 4.01Å; F163-F229 AromaticContact CD1-CE1 3.73Å; F163-F229 HydrophobicContact CD1-CE1 3.73Å; F163-F229 HydrophobicContact CD1-CZ 4.45Å; F163-F229 HydrophobicContact CE1-CE1 4.45Å; R170-F229 HydrophobicContact CB-CE2 4.26Å; R170-F229 HydrophobicContact CB-CZ 4.38Å; L173-F229 HydrophobicContact CD1-CD1 4.26Å; L173-F229 HydrophobicContact CD1-CE1 4.04Å; L173-F229 HydrophobicContact CD1-CE2 4.5Å; L173-F229 HydrophobicContact CD1-CZ 4.17Å; L173-F229 HydrophobicContact CD2-CE1 4.29Å; L173-F229 HydrophobicContact CD2-CE2 4.36Å; L173-F229 HydrophobicContact CD2-CZ 3.82Å; L173-F229 HydrophobicContact CG-CE1 3.82Å; L173-F229 HydrophobicContact CG-CZ 3.88Å; H225-F229 PolarHBondContact O-N 3.26Å; H225-F229 VanDerWaalsContact O-N 3.14Å; R226-F229 PolarHBondContact O-N 3.21Å; Q227-F229 VanDerWaalsContact C-N 3.28Å; Q227-F229 PolarHBondContact O-N 3.44Å; F229-W231 PolarHBondContact O-N 3.01Å; F229-I232 VanDerWaalsContact O-CB 3.29Å; F229-I232 WeakPolarHBondContact O-CB 3.46Å; F229-I232 VanDerWaalsContact O-CG2 3.24Å; F229-I232 WeakPolarHBondContact O-CG2 3.34Å; F229-I232 PolarHBondContact O-N 2.96Å; F229-I232 VanDerWaalsContact O-N 3.08Å
230C98.7Very high98Very high8 Ų832.8 Ų32.85%0.05416%0.164CC..Hα-helixtrans-67.4-18.3179.9-60.30000113D159 F163 R226 Q227D159-C230 VanDerWaalsContact C-SG 3.56Å; F163-C230 HydrophobicContact CB-CB 4.44Å; F163-C230 HydrophobicContact CD1-CB 4.46Å; F163-C230 HydrophobicContact CD2-CB 4.25Å; F163-C230 WeakPolarHBondContact CE2-O 3.43Å; F163-C230 HydrophobicContact CG-CB 4.11Å; F163-C230 VanDerWaalsContact CZ-O 3.25Å; F163-C230 WeakPolarHBondContact CZ-O 3.49Å; R226-C230 PolarHBondContact O-N 2.77Å; R226-C230 PolarHBondContact O-SG 2.96Å; Q227-C230 CarbonylContact O-C 3.55Å; Q227-C230 PolarHBondContact O-N 3.04Å; Q227-C230 VanDerWaalsContact O-N 3.13Å
231W98.6Very high98Very high19 Ų1934 Ų347%0.07217%0.171CC..THydrogen-bonded Turntrans-95.57.1175.3-62.2-17.7000113.7F24 E28 Q227 L228 F229 D233 K234 W235F24-W231 HydrophobicContact CE1-CB 4.12Å; F24-W231 HydrophobicContact CE1-CE3 4.21Å; E28-W231 HydrophobicContact CB-CE3 4.27Å; E28-W231 HydrophobicContact CB-CH2 4.04Å; E28-W231 HydrophobicContact CB-CZ3 3.7Å; Q227-W231 HydrophobicContact CB-CD2 4.17Å; Q227-W231 HydrophobicContact CB-CE3 4.03Å; Q227-W231 HydrophobicContact CB-CH2 3.69Å; Q227-W231 HydrophobicContact CB-CZ2 3.81Å; Q227-W231 HydrophobicContact CB-CZ3 3.8Å; Q227-W231 HydrophobicContact CG-CH2 3.94Å; Q227-W231 HydrophobicContact CG-CZ2 3.84Å; Q227-W231 WeakPolarHBondContact O-CB 3.48Å; Q227-W231 PolarHBondContact O-N 3.14Å; L228-W231 PolarHBondContact O-N 3.34Å; F229-W231 PolarHBondContact O-N 3.01Å; W231-D233 PolarHBondContact O-N 2.95Å; W231-D233 VanDerWaalsContact O-N 3.12Å; W231-K234 HydrophobicContact CB-CD 4.26Å; W231-K234 HydrophobicContact CG-CD 4.31Å; W231-K234 WeakPolarHBondContact O-CA 3.44Å; W231-K234 VanDerWaalsContact O-CB 3.27Å; W231-K234 WeakPolarHBondContact O-CB 3.36Å; W231-K234 PolarHBondContact O-N 2.78Å; W231-W235 VanDerWaalsContact C-CD1 3.47Å; W231-W235 PolarHBondContact O-N 2.87Å; W231-W235 PolarHBondContact O-NE1 3.05Å
232I98.4Very high97.9Very high1 Ų134.6 Ų34.61%0.00518%0.175CC..Hα-helixtrans-51-40.3-177.1-168.1166.1000113.3F163 T168 L228 F229 K234 W235 V236F163-I232 HydrophobicContact CE1-CG2 3.64Å; F163-I232 HydrophobicContact CZ-CG2 3.95Å; T168-I232 HydrophobicContact CG2-CD1 4.17Å; T168-I232 HydrophobicContact CG2-CG1 4.37Å; L228-I232 PolarHBondContact O-N 2.94Å; F229-I232 VanDerWaalsContact O-CB 3.29Å; F229-I232 WeakPolarHBondContact O-CB 3.46Å; F229-I232 VanDerWaalsContact O-CG2 3.24Å; F229-I232 WeakPolarHBondContact O-CG2 3.34Å; F229-I232 PolarHBondContact O-N 2.96Å; F229-I232 VanDerWaalsContact O-N 3.08Å; I232-K234 PolarHBondContact O-N 3.24Å; I232-K234 VanDerWaalsContact O-N 3.14Å; I232-W235 HydrophobicContact CB-CZ2 3.87Å; I232-W235 HydrophobicContact CD1-CH2 4.1Å; I232-W235 HydrophobicContact CD1-CZ2 4.18Å; I232-W235 HydrophobicContact CG1-CH2 3.78Å; I232-W235 HydrophobicContact CG1-CZ2 3.63Å; I232-W235 HydrophobicContact CG1-CZ3 4.4Å; I232-W235 PolarHBondContact O-N 3.31Å; I232-W235 VanDerWaalsContact O-N 3.15Å; I232-V236 HydrophobicContact CG1-CB 3.95Å; I232-V236 HydrophobicContact CG1-CG2 4.31Å; I232-V236 VanDerWaalsContact O-CB 3.23Å; I232-V236 WeakPolarHBondContact O-CB 3.25Å; I232-V236 VanDerWaalsContact O-CG1 3.28Å; I232-V236 WeakPolarHBondContact O-CG1 3.45Å; I232-V236 PolarHBondContact O-N 2.77Å
233D98.5Very high97.8Very high32 Ų3234.6 Ų34.617%0.17118%0.175CC..Hα-helixtrans-64.8-20.6178.7-71-22000113.3S165 V166 K167 W231S165-D233 WeakPolarHBondContact CA-OD2 3.39Å; S165-D233 WeakPolarHBondContact CB-OD1 3.47Å; S165-D233 PolarHBondContact OG-OD1 2.9Å; V166-D233 PolarHBondContact N-OD1 3.11Å; V166-D233 PolarHBondContact N-OD2 2.82Å; K167-D233 WeakPolarHBondContact CB-OD1 3.32Å; K167-D233 HydrophobicContact CD-CB 4.28Å; K167-D233 WeakPolarHBondContact CD-O 3.38Å; K167-D233 WeakPolarHBondContact CE-O 3.16Å; K167-D233 HydrophobicContact CG-CB 4.31Å; K167-D233 PolarHBondContact N-OD1 2.7Å; K167-D233 VanDerWaalsContact N-OD1 3.08Å; K167-D233 PolarHBondContact NZ-O 2.81Å; W231-D233 PolarHBondContact O-N 2.95Å; W231-D233 VanDerWaalsContact O-N 3.12Å
234K98.4Very high97.5Very high116 Ų11637.4 Ų37.450%0.50419%0.185SC..Hα-helixtrans-84.1-27.1177.7-56.9-177.4179.2176.70112.9F24 W231 I232F24-K234 HydrophobicContact CE1-CB 3.99Å; F24-K234 HydrophobicContact CE1-CD 4.31Å; F24-K234 HydrophobicContact CE2-CB 4.15Å; F24-K234 HydrophobicContact CZ-CB 3.52Å; F24-K234 HydrophobicContact CZ-CD 3.96Å; F24-K234 HydrophobicContact CZ-CG 4.4Å; W231-K234 HydrophobicContact CB-CD 4.26Å; W231-K234 HydrophobicContact CG-CD 4.31Å; W231-K234 WeakPolarHBondContact O-CA 3.44Å; W231-K234 VanDerWaalsContact O-CB 3.27Å; W231-K234 WeakPolarHBondContact O-CB 3.36Å; W231-K234 PolarHBondContact O-N 2.78Å; I232-K234 PolarHBondContact O-N 3.24Å; I232-K234 VanDerWaalsContact O-N 3.14Å
235W98.3Very high97.3Very high2 Ų242.5 Ų42.51%0.00820%0.203CC..Hα-helixtrans-121.3-17.5-170.962.9-108.6000115.7E17 G21 F24 L228 W231 I232 D237 L238E17-W235 HydrophobicContact CB-CH2 4.25Å; E17-W235 HydrophobicContact CB-CZ3 3.96Å; E17-W235 VanDerWaalsContact O-CZ3 3.31Å; E17-W235 WeakPolarHBondContact O-CZ3 3.39Å; G21-W235 VanDerWaalsContact CA-CE3 3.47Å; F24-W235 HydrophobicContact CB-CB 3.75Å; F24-W235 HydrophobicContact CB-CG 4.34Å; F24-W235 HydrophobicContact CD1-CB 3.84Å; F24-W235 AromaticContact CD1-CD1 3.68Å; F24-W235 HydrophobicContact CD1-CG 4.11Å; F24-W235 HydrophobicContact CD2-CB 3.88Å; F24-W235 HydrophobicContact CE1-CB 4.45Å; F24-W235 HydrophobicContact CE2-CB 4.46Å; F24-W235 HydrophobicContact CG-CB 3.54Å; F24-W235 HydrophobicContact CG-CG 4.23Å; L228-W235 HydrophobicContact CD2-CZ2 3.83Å; L228-W235 HydrophobicContact CG-CZ2 4.45Å; L228-W235 PolarHBondContact O-NE1 3.3Å; W231-W235 VanDerWaalsContact C-CD1 3.47Å; W231-W235 PolarHBondContact O-N 2.87Å; W231-W235 PolarHBondContact O-NE1 3.05Å; I232-W235 HydrophobicContact CB-CZ2 3.87Å; I232-W235 HydrophobicContact CD1-CH2 4.1Å; I232-W235 HydrophobicContact CD1-CZ2 4.18Å; I232-W235 HydrophobicContact CG1-CH2 3.78Å; I232-W235 HydrophobicContact CG1-CZ2 3.63Å; I232-W235 HydrophobicContact CG1-CZ3 4.4Å; I232-W235 PolarHBondContact O-N 3.31Å; I232-W235 VanDerWaalsContact O-N 3.15Å; W235-D237 PolarHBondContact O-N 3.18Å; W235-D237 VanDerWaalsContact O-N 3.17Å; W235-L238 HydrophobicContact CB-CD1 4.08Å; W235-L238 WeakPolarHBondContact O-CB 3.43Å; W235-L238 PolarHBondContact O-N 3.18Å
236V98.1Very high97.1Very high31 Ų3144.4 Ų44.419%0.18821%0.212CC..THydrogen-bonded Turntrans-61.5-28.6-17268.10000114.1K167 T168 I232K167-V236 HydrophobicContact CB-CG1 4.28Å; K167-V236 HydrophobicContact CD-CG1 3.95Å; T168-V236 HydrophobicContact CG2-CB 4.48Å; T168-V236 HydrophobicContact CG2-CG1 4.23Å; T168-V236 HydrophobicContact CG2-CG2 3.92Å; I232-V236 HydrophobicContact CG1-CB 3.95Å; I232-V236 HydrophobicContact CG1-CG2 4.31Å; I232-V236 VanDerWaalsContact O-CB 3.23Å; I232-V236 WeakPolarHBondContact O-CB 3.25Å; I232-V236 VanDerWaalsContact O-CG1 3.28Å; I232-V236 WeakPolarHBondContact O-CG1 3.45Å; I232-V236 PolarHBondContact O-N 2.77Å
237D97.8Very high96.7Very high111 Ų11145.4 Ų45.459%0.59422%0.217SC*.THydrogen-bonded Turntrans-94.8-0.7178.9-55.5-43000113.3K167 W235K167-D237 VanDerWaalsContact CD-OD2 3.23Å; K167-D237 WeakPolarHBondContact CD-OD2 3.26Å; K167-D237 VanDerWaalsContact CE-OD2 3.31Å; K167-D237 WeakPolarHBondContact CE-OD2 3.41Å; K167-D237 IonicContact NZ-OD2 3.47Å; K167-D237 PolarHBondContact NZ-OD2 3.29Å; W235-D237 PolarHBondContact O-N 3.18Å; W235-D237 VanDerWaalsContact O-N 3.17Å
238L98Very high96.3Very high44 Ų4446.7 Ų46.723%0.2323%0.232CC..  trans-77.5143179.5-60.4179.2000110.2V20 F24 W235 D242 I243 M246V20-L238 HydrophobicContact CG1-CB 3.81Å; V20-L238 WeakPolarHBondContact CG1-O 3.17Å; F24-L238 HydrophobicContact CD2-CD1 3.66Å; F24-L238 HydrophobicContact CE2-CD1 4.22Å; W235-L238 HydrophobicContact CB-CD1 4.08Å; W235-L238 WeakPolarHBondContact O-CB 3.43Å; W235-L238 PolarHBondContact O-N 3.18Å; L238-D242 HydrophobicContact CB-CB 4.25Å; L238-D242 HydrophobicContact CD2-CB 4.05Å; L238-I243 HydrophobicContact CB-CD1 4.47Å; L238-I243 HydrophobicContact CD1-CD1 4.04Å; L238-M246 HydrophobicContact CD1-SD 3.8Å
239N96.7Very high96Very high77 Ų7752.6 Ų52.641%0.41226%0.259SS..  trans-99.8173.5168.46555.5000111.1D241 D242 I243N239-D241 VanDerWaalsContact C-N 3.27Å; N239-D241 PolarHBondContact O-N 2.94Å; N239-D241 WeakPolarHBondContact OD1-CA 3.48Å; N239-D241 VanDerWaalsContact OD1-CB 3.3Å; N239-D241 WeakPolarHBondContact OD1-CB 3.27Å; N239-D241 PolarHBondContact OD1-N 3.01Å; N239-D242 PolarHBondContact N-OD2 3.23Å; N239-D242 PolarHBondContact ND2-OD2 3.42Å; N239-D242 WeakPolarHBondContact O-CB 3.44Å; N239-D242 PolarHBondContact O-N 2.82Å; N239-D242 VanDerWaalsContact OD1-CG 3.3Å; N239-D242 PolarHBondContact OD1-N 3.46Å; N239-D242 PolarHBondContact OD1-OD2 3Å; N239-I243 WeakPolarHBondContact O-CG1 3.48Å; N239-I243 PolarHBondContact O-N 3.47Å; N239-I243 VanDerWaalsContact O-N 3.11Å
240M94Very high95.7Very high53 Ų5352.7 Ų52.726%0.26126%0.26SS..Hα-helixtrans-62.6-30.7-179.8-74-58.4-51.800113.6Q19 V20 L23 I243 R244Q19-M240 HydrophobicContact CG-SD 4.22Å; V20-M240 HydrophobicContact CG2-SD 4.22Å; L23-M240 HydrophobicContact CD1-CE 3.61Å; L23-M240 HydrophobicContact CD1-SD 4.16Å; M240-I243 WeakPolarHBondContact O-CB 3.23Å; M240-I243 PolarHBondContact O-N 3.23Å; M240-R244 WeakPolarHBondContact O-CG 3.3Å; M240-R244 PolarHBondContact O-N 3.37Å
241D95.5Very high95.3Very high116 Ų11655.5 Ų55.562%0.6227%0.273SS*.Hα-helixtrans-69.4-38.1176.6-64.9-26000111.1N239 I243 R244 R245N239-D241 VanDerWaalsContact C-N 3.27Å; N239-D241 PolarHBondContact O-N 2.94Å; N239-D241 WeakPolarHBondContact OD1-CA 3.48Å; N239-D241 VanDerWaalsContact OD1-CB 3.3Å; N239-D241 WeakPolarHBondContact OD1-CB 3.27Å; N239-D241 PolarHBondContact OD1-N 3.01Å; D241-I243 VanDerWaalsContact C-N 3.32Å; D241-R244 PolarHBondContact O-N 3.48Å; D241-R245 WeakPolarHBondContact O-CG 3.24Å; D241-R245 PolarHBondContact O-N 3.42Å; D241-R245 VanDerWaalsContact O-N 3.12Å; D241-R245 PolarHBondContact O-NH1 3.15Å
242D96.9Very high94.9Very high30 Ų3061.6 Ų61.616%0.1630%0.3CS..Hα-helixtrans-60.2-45.5172.6-53.8-35.1000110.4L238 N239 R244 R245 M246L238-D242 HydrophobicContact CB-CB 4.25Å; L238-D242 HydrophobicContact CD2-CB 4.05Å; N239-D242 PolarHBondContact N-OD2 3.23Å; N239-D242 PolarHBondContact ND2-OD2 3.42Å; N239-D242 WeakPolarHBondContact O-CB 3.44Å; N239-D242 PolarHBondContact O-N 2.82Å; N239-D242 VanDerWaalsContact OD1-CG 3.3Å; N239-D242 PolarHBondContact OD1-N 3.46Å; N239-D242 PolarHBondContact OD1-OD2 3Å; D242-R244 PolarHBondContact O-N 3.5Å; D242-R245 PolarHBondContact O-N 3.44Å; D242-R245 IonicContact OD1-CZ 2.7Å; D242-R245 VanDerWaalsContact OD1-CZ 3.31Å; D242-R245 IonicContact OD1-NH1 3.31Å; D242-R245 PolarHBondContact OD1-NH1 3.31Å; D242-R245 VanDerWaalsContact OD1-NH1 3.16Å; D242-R245 IonicContact OD1-NH2 3.16Å; D242-R245 PolarHBondContact OD1-NH2 3.4Å; D242-M246 WeakPolarHBondContact O-CG 3.49Å; D242-M246 PolarHBondContact O-N 3.47Å
243I95.9Very high94.7Very high2 Ų265.1 Ų65.11%0.0132%0.316CS..Hα-helixtrans-59.6-44.2176.4-65.8-60.7000111.7V20 L23 F24 L238 N239 M240 D241 R245 M246 E247V20-I243 HydrophobicContact CG1-CD1 3.88Å; V20-I243 HydrophobicContact CG1-CG1 3.89Å; L23-I243 HydrophobicContact CB-CG2 3.49Å; L23-I243 VanDerWaalsContact CB-CG2 3.49Å; L23-I243 HydrophobicContact CD1-CG2 3.69Å; L23-I243 HydrophobicContact CG-CG2 4.2Å; F24-I243 HydrophobicContact CB-CD1 3.95Å; L238-I243 HydrophobicContact CB-CD1 4.47Å; L238-I243 HydrophobicContact CD1-CD1 4.04Å; N239-I243 WeakPolarHBondContact O-CG1 3.48Å; N239-I243 PolarHBondContact O-N 3.47Å; N239-I243 VanDerWaalsContact O-N 3.11Å; M240-I243 WeakPolarHBondContact O-CB 3.23Å; M240-I243 PolarHBondContact O-N 3.23Å; D241-I243 VanDerWaalsContact C-N 3.32Å; I243-R245 VanDerWaalsContact C-N 3.33Å; I243-R245 PolarHBondContact O-N 3.06Å; I243-M246 PolarHBondContact O-N 3.18Å; I243-E247 HydrophobicContact CG2-CG 4.3Å; I243-E247 WeakPolarHBondContact O-CG 3.22Å; I243-E247 PolarHBondContact O-N 3.38Å
244R92.6Very high94.3Very high80 Ų8063.7 Ų63.730%0.30231%0.308SS..Hα-helixtrans-63.6-37.4178.5-66.4-48.4178.1-165.3-3.1112.7Q56 M240 D241 D242 E247 A248Q56-R244 VanDerWaalsContact OE1-NH2 3.15Å; M240-R244 WeakPolarHBondContact O-CG 3.3Å; M240-R244 PolarHBondContact O-N 3.37Å; D241-R244 PolarHBondContact O-N 3.48Å; D242-R244 PolarHBondContact O-N 3.5Å; R244-E247 WeakPolarHBondContact CD-OE2 3.48Å; R244-E247 IonicContact CZ-OE2 2.78Å; R244-E247 IonicContact NE-OE2 2.7Å; R244-E247 IonicContact NH1-OE1 3.49Å; R244-E247 PolarHBondContact NH1-OE1 3.29Å; R244-E247 IonicContact NH1-OE2 2.83Å; R244-E247 PolarHBondContact NH1-OE2 3.24Å; R244-A248 PolarHBondContact O-N 2.9Å
245R94.1Very high93.9Very high135 Ų13562.7 Ų62.751%0.50931%0.306SS..Hα-helixtrans-64.8-46.4173.2-65.7-169.2-48.5-88.34.7111D241 D242 I243 E247 A248 E249D241-R245 WeakPolarHBondContact O-CG 3.24Å; D241-R245 PolarHBondContact O-N 3.42Å; D241-R245 VanDerWaalsContact O-N 3.12Å; D241-R245 PolarHBondContact O-NH1 3.15Å; D242-R245 PolarHBondContact O-N 3.44Å; D242-R245 IonicContact OD1-CZ 2.7Å; D242-R245 VanDerWaalsContact OD1-CZ 3.31Å; D242-R245 IonicContact OD1-NH1 3.31Å; D242-R245 PolarHBondContact OD1-NH1 3.31Å; D242-R245 VanDerWaalsContact OD1-NH1 3.16Å; D242-R245 IonicContact OD1-NH2 3.16Å; D242-R245 PolarHBondContact OD1-NH2 3.4Å; I243-R245 VanDerWaalsContact C-N 3.33Å; I243-R245 PolarHBondContact O-N 3.06Å; R245-E247 PolarHBondContact O-N 3.01Å; R245-A248 PolarHBondContact O-N 3.19Å; R245-E249 WeakPolarHBondContact O-CG 3.43Å; R245-E249 PolarHBondContact O-N 2.71Å
246M93.7Very high93.4Very high39 Ų3968.4 Ų68.419%0.19233%0.332CS..Hα-helixtrans-60.8-40.8178-73.5-173.462.500113.1F24 L238 D242 I243 A248 E249 T250F24-M246 HydrophobicContact CD2-CE 3.45Å; F24-M246 VanDerWaalsContact CD2-CE 3.45Å; F24-M246 HydrophobicContact CD2-SD 3.94Å; F24-M246 HydrophobicContact CE2-CE 3.56Å; F24-M246 HydrophobicContact CE2-SD 4.29Å; L238-M246 HydrophobicContact CD1-SD 3.8Å; D242-M246 WeakPolarHBondContact O-CG 3.49Å; D242-M246 PolarHBondContact O-N 3.47Å; I243-M246 PolarHBondContact O-N 3.18Å; M246-A248 VanDerWaalsContact C-N 3.32Å; M246-A248 PolarHBondContact O-N 3.48Å; M246-E249 PolarHBondContact O-N 2.78Å; M246-T250 VanDerWaalsContact O-CB 3.22Å; M246-T250 WeakPolarHBondContact O-CB 3.3Å; M246-T250 PolarHBondContact O-N 2.8Å; M246-T250 PolarHBondContact O-OG1 2.86Å
247E90.6Very high93Very high27 Ų2768.9 Ų68.913%0.12633%0.334CS..Hα-helixtrans-62.6-40.4176.7-75.5179.6151.600111.6N45 I243 R244 R245 T250 Q251N45-E247 PolarHBondContact ND2-OE2 3.08Å; I243-E247 HydrophobicContact CG2-CG 4.3Å; I243-E247 WeakPolarHBondContact O-CG 3.22Å; I243-E247 PolarHBondContact O-N 3.38Å; R244-E247 WeakPolarHBondContact CD-OE2 3.48Å; R244-E247 IonicContact CZ-OE2 2.78Å; R244-E247 IonicContact NE-OE2 2.7Å; R244-E247 IonicContact NH1-OE1 3.49Å; R244-E247 PolarHBondContact NH1-OE1 3.29Å; R244-E247 IonicContact NH1-OE2 2.83Å; R244-E247 PolarHBondContact NH1-OE2 3.24Å; R245-E247 PolarHBondContact O-N 3.01Å; E247-T250 PolarHBondContact O-N 3.4Å; E247-Q251 PolarHBondContact O-N 2.84Å
248A90.1Very high92.5Very high50 Ų5066.1 Ų66.141%0.41332%0.315SS..Hα-helixtrans-68.1-38.9177.800000112.4R244 R245 M246R244-A248 PolarHBondContact O-N 2.9Å; R245-A248 PolarHBondContact O-N 3.19Å; M246-A248 VanDerWaalsContact C-N 3.32Å; M246-A248 PolarHBondContact O-N 3.48Å
249E93.1Very high92Very high127 Ų12770.5 Ų70.559%0.59333%0.332SS*.Hα-helixtrans-65.9-46.4172.7-71.4171.8-174.800111.1R245 M246 Q251 K252 E253R245-E249 WeakPolarHBondContact O-CG 3.43Å; R245-E249 PolarHBondContact O-N 2.71Å; M246-E249 PolarHBondContact O-N 2.78Å; E249-Q251 VanDerWaalsContact C-N 3.31Å; E249-Q251 PolarHBondContact O-N 2.96Å; E249-K252 PolarHBondContact O-N 3.01Å; E249-K252 VanDerWaalsContact O-N 3.12Å; E249-E253 PolarHBondContact O-N 3Å
250T92.1Very high91.3Very high7 Ų773.4 Ų73.44%0.04334%0.343CS..Hα-helixtrans-60.8-39.5179.2-60.90000111.5A27 K31 M246 E247 K252 E253 L254A27-T250 HydrophobicContact CB-CG2 3.98Å; K31-T250 VanDerWaalsContact CE-OG1 3.27Å; K31-T250 WeakPolarHBondContact CE-OG1 3.35Å; K31-T250 HydrophobicContact CG-CG2 4.21Å; M246-T250 VanDerWaalsContact O-CB 3.22Å; M246-T250 WeakPolarHBondContact O-CB 3.3Å; M246-T250 PolarHBondContact O-N 2.8Å; M246-T250 PolarHBondContact O-OG1 2.86Å; E247-T250 PolarHBondContact O-N 3.4Å; T250-K252 VanDerWaalsContact C-N 3.28Å; T250-K252 PolarHBondContact O-N 3.17Å; T250-E253 PolarHBondContact O-N 2.92Å; T250-L254 HydrophobicContact CG2-CD1 3.79Å; T250-L254 HydrophobicContact CG2-CG 3.9Å; T250-L254 WeakPolarHBondContact O-CB 3.3Å; T250-L254 WeakPolarHBondContact O-CG 3.46Å; T250-L254 PolarHBondContact O-N 3.01Å
251Q90.5Very high90.6Very high67 Ų6774.2 Ų74.231%0.31337%0.365SS..Hα-helixtrans-56.5-42.8176.3175.8170.616.200112.1V42 E247 E249 E255V42-Q251 HydrophobicContact CB-CB 4.45Å; V42-Q251 HydrophobicContact CB-CG 4.05Å; V42-Q251 HydrophobicContact CG1-CG 4.42Å; V42-Q251 PolarHBondContact O-NE2 3.04Å; E247-Q251 PolarHBondContact O-N 2.84Å; E249-Q251 VanDerWaalsContact C-N 3.31Å; E249-Q251 PolarHBondContact O-N 2.96Å; Q251-E255 PolarHBondContact O-N 3.13Å
252K90.6Very high90.1Very high146 Ų14676.7 Ų76.764%0.63537%0.373SS*.Hα-helixtrans-69.5-46.2177.7-63.8176.7-177.6176.10111.3E249 T250 L254 E255 E256E249-K252 PolarHBondContact O-N 3.01Å; E249-K252 VanDerWaalsContact O-N 3.12Å; T250-K252 VanDerWaalsContact C-N 3.28Å; T250-K252 PolarHBondContact O-N 3.17Å; K252-L254 VanDerWaalsContact C-N 3.33Å; K252-L254 PolarHBondContact O-N 3.01Å; K252-E255 WeakPolarHBondContact O-CB 3.36Å; K252-E255 PolarHBondContact O-N 3.42Å; K252-E255 VanDerWaalsContact O-N 3.15Å; K252-E256 PolarHBondContact O-N 3.28Å; K252-E256 VanDerWaalsContact O-N 3.12Å
253E92.8Very high89.5Confident75 Ų7578.3 Ų78.335%0.3538%0.384SS..Hα-helixtrans-60-43.2-179.9-167.7-177.6172.700111.4K31 E249 T250 E255 E256 L257K31-E253 WeakPolarHBondContact CD-OE2 3.32Å; K31-E253 WeakPolarHBondContact CE-OE2 3.18Å; K31-E253 IonicContact NZ-OE2 2.68Å; K31-E253 PolarHBondContact NZ-OE2 2.93Å; E249-E253 PolarHBondContact O-N 3Å; T250-E253 PolarHBondContact O-N 2.92Å; E253-E255 VanDerWaalsContact C-N 3.31Å; E253-E255 PolarHBondContact O-N 3.29Å; E253-E256 PolarHBondContact O-N 3.31Å; E253-L257 HydrophobicContact CG-CD1 3.88Å; E253-L257 HydrophobicContact CG-CG 4.24Å; E253-L257 WeakPolarHBondContact O-CB 3.37Å; E253-L257 WeakPolarHBondContact O-CG 3.27Å; E253-L257 PolarHBondContact O-N 2.7Å
254L91Very high89.1Confident2 Ų283.4 Ų83.41%0.0140%0.403CS..Hα-helixtrans-61.3-38.5176.5-70.3175.4000112.5S30 K31 T34 I40 V42 T250 K252 R258S30-L254 VanDerWaalsContact C-CD2 3.49Å; S30-L254 WeakPolarHBondContact O-CD2 3.47Å; K31-L254 HydrophobicContact CB-CD2 4.46Å; K31-L254 HydrophobicContact CG-CD2 4.05Å; T34-L254 HydrophobicContact CG2-CD2 4.14Å; I40-L254 HydrophobicContact CG2-CD1 4.43Å; V42-L254 HydrophobicContact CG2-CD1 4Å; T250-L254 HydrophobicContact CG2-CD1 3.79Å; T250-L254 HydrophobicContact CG2-CG 3.9Å; T250-L254 WeakPolarHBondContact O-CB 3.3Å; T250-L254 WeakPolarHBondContact O-CG 3.46Å; T250-L254 PolarHBondContact O-N 3.01Å; K252-L254 VanDerWaalsContact C-N 3.33Å; K252-L254 PolarHBondContact O-N 3.01Å; L254-R258 VanDerWaalsContact O-CB 3.24Å; L254-R258 WeakPolarHBondContact O-CB 3.44Å; L254-R258 PolarHBondContact O-N 2.84Å
255E88.8Confident88.7Confident96 Ų9681.9 Ų81.945%0.44941%0.412SS..Hα-helixtrans-65.3-41.9177.2-171.5179.8174.400111.7Q251 K252 E253 K259Q251-E255 PolarHBondContact O-N 3.13Å; K252-E255 WeakPolarHBondContact O-CB 3.36Å; K252-E255 PolarHBondContact O-N 3.42Å; K252-E255 VanDerWaalsContact O-N 3.15Å; E253-E255 VanDerWaalsContact C-N 3.31Å; E253-E255 PolarHBondContact O-N 3.29Å; E255-K259 HydrophobicContact CG-CD 4.49Å; E255-K259 WeakPolarHBondContact O-CG 3.12Å; E255-K259 PolarHBondContact O-N 2.83Å; E255-K259 WeakPolarHBondContact OE1-CE 3.17Å; E255-K259 IonicContact OE1-NZ 3.48Å; E255-K259 PolarHBondContact OE1-NZ 3.18Å
256E89.6Confident88.1Confident121 Ų12178 Ų7857%0.56540%0.403SS*.Hα-helixtrans-65.2-49.7175.9-69176.6177.500111.3K252 E253 R258 K259 Q260K252-E256 PolarHBondContact O-N 3.28Å; K252-E256 VanDerWaalsContact O-N 3.12Å; E253-E256 PolarHBondContact O-N 3.31Å; E256-R258 VanDerWaalsContact C-N 3.28Å; E256-R258 PolarHBondContact O-N 3.25Å; E256-K259 PolarHBondContact O-N 2.97Å; E256-K259 VanDerWaalsContact O-N 3.12Å; E256-Q260 WeakPolarHBondContact O-CB 3.43Å; E256-Q260 PolarHBondContact O-N 3.4Å; E256-Q260 VanDerWaalsContact O-N 3.08Å
257L89.1Confident87.4Confident41 Ų4178.5 Ų78.522%0.21541%0.411CS..Hα-helixtrans-61.3-35.1177.9-70.5175.3000112K31 T34 G35 E253K31-L257 HydrophobicContact CB-CD1 4.37Å; T34-L257 HydrophobicContact CG2-CB 4.32Å; G35-L257 WeakPolarHBondContact CA-O 3.32Å; E253-L257 HydrophobicContact CG-CD1 3.88Å; E253-L257 HydrophobicContact CG-CG 4.24Å; E253-L257 WeakPolarHBondContact O-CB 3.37Å; E253-L257 WeakPolarHBondContact O-CG 3.27Å; E253-L257 PolarHBondContact O-N 2.7Å
258R87.9Confident86.8Confident54 Ų5477.6 Ų77.620%0.20441%0.408CS..Hα-helixtrans-68.7-36.1176.6-168.8178.57195.1-8.6111.7T34 G37 E41 L254 E256T34-R258 HydrophobicContact CG2-CB 3.82Å; T34-R258 HydrophobicContact CG2-CG 4.46Å; G37-R258 WeakPolarHBondContact CA-O 3.43Å; G37-R258 PolarHBondContact N-O 2.53Å; E41-R258 IonicContact OE1-NH2 3.95Å; E41-R258 IonicContact OE2-CZ 3.52Å; E41-R258 IonicContact OE2-NE 2.78Å; E41-R258 IonicContact OE2-NH2 3.45Å; E41-R258 PolarHBondContact OE2-NH2 3.41Å; L254-R258 VanDerWaalsContact O-CB 3.24Å; L254-R258 WeakPolarHBondContact O-CB 3.44Å; L254-R258 PolarHBondContact O-N 2.84Å; E256-R258 VanDerWaalsContact C-N 3.28Å; E256-R258 PolarHBondContact O-N 3.25Å
259K86.3Confident85.6Confident136 Ų13676.7 Ų76.759%0.59140%0.4SS*.Hα-helixtrans-79.2-17.7-179.4-70.1173.9-172.1170.10113.3E255 E256E255-K259 HydrophobicContact CG-CD 4.49Å; E255-K259 WeakPolarHBondContact O-CG 3.12Å; E255-K259 PolarHBondContact O-N 2.83Å; E255-K259 WeakPolarHBondContact OE1-CE 3.17Å; E255-K259 IonicContact OE1-NZ 3.48Å; E255-K259 PolarHBondContact OE1-NZ 3.18Å; E256-K259 PolarHBondContact O-N 2.97Å; E256-K259 VanDerWaalsContact O-N 3.12Å
260Q82.6Confident84Confident138 Ų13878.3 Ų78.365%0.64541%0.413SS*.SBendtrans-128.3167.4-171.5-58.8-177.4800111.9G36 E256G36-Q260 PolarHBondContact N-O 3.46Å; E256-Q260 WeakPolarHBondContact O-CB 3.43Å; E256-Q260 PolarHBondContact O-N 3.4Å; E256-Q260 VanDerWaalsContact O-N 3.08Å
261G79.2Confident82.2Confident69 Ų6984.2 Ų84.271%0.71144%0.44SS*.SBendtrans73.1-163.7174.300000115.4G36G36-G261 WeakPolarHBondContact CA-O 3.47Å
262E84.3Confident81.8Confident169 Ų16985.1 Ų85.179%0.7945%0.446SS*.  trans-106.6157.7-177.3-62.8-177.2165.700111.5G35 G36 R264G35-E262 CarbonylContact C-O 3.53Å; G35-E262 WeakPolarHBondContact CA-O 3.22Å; G36-E262 PolarHBondContact N-O 3.11Å; E262-R264 PolarHBondContact O-N 2.94Å
263V84.7Confident81.4Confident64 Ų6481.9 Ų81.939%0.38844%0.436SS..  trans-63.2133.3172.21790000109.2E38E38-V263 HydrophobicContact CB-CG2 4.48Å; E38-V263 HydrophobicContact CG-CG2 4.4Å
264R87.4Confident80.7Confident109 Ų10982.3 Ų82.341%0.41144%0.441SS..  trans-146.3172.4-176.560.1177.2166-168.8-5.3112.1T34 K67 E262T34-R264 PolarHBondContact O-NE 2.84Å; T34-R264 PolarHBondContact O-NH2 3.3Å; K67-R264 WeakPolarHBondContact CE-O 3.15Å; K67-R264 PolarHBondContact NZ-O 3.14Å; E262-R264 PolarHBondContact O-N 2.94Å
265G84.1Confident80.1Confident48 Ų4887 Ų8750%0.49547%0.467SS..SBendtrans89.6-158.9179.700000112.5N32 E33N32-G265 WeakPolarHBondContact O-CA 3.46Å; E33-G265 WeakPolarHBondContact OE2-CA 3.37Å
266T81.7Confident79.6Confident53 Ų5386.4 Ų86.433%0.32547%0.468SS..  trans-73.4131.7-172.4-49.40000110.9E33 R219E33-T266 VanDerWaalsContact CD-N 3.25Å; E33-T266 WeakPolarHBondContact OE1-CB 3.3Å; E33-T266 PolarHBondContact OE1-N 2.97Å; E33-T266 PolarHBondContact OE1-OG1 3.35Å; E33-T266 PolarHBondContact OE2-N 3.11Å; R219-T266 VanDerWaalsContact CZ-CG2 3.44Å; R219-T266 VanDerWaalsContact NH2-CG2 3.31Å
267S78.8Confident78.9Confident50 Ų5084.1 Ų84.135%0.3546%0.461SS..  trans-116.5142.4172.1-176.80000110.6R219 A269R219-S267 PolarHBondContact NH1-O 3.33Å; S267-A269 WeakPolarHBondContact OG-CB 3.38Å; S267-A269 PolarHBondContact OG-N 3.14Å
268A78.4Confident78.2Confident8 Ų887.2 Ų87.27%0.06648%0.479CS..  trans-1111416600000111.4K67 P69 F212 D270 Q271K67-A268 PolarHBondContact O-N 3.32Å; P69-A268 WeakPolarHBondContact CA-O 3.17Å; P69-A268 HydrophobicContact CG-CB 4.15Å; P69-A268 WeakPolarHBondContact CG-O 3.38Å; F212-A268 HydrophobicContact CZ-CB 4.09Å; A268-D270 VanDerWaalsContact C-N 3.25Å; A268-D270 PolarHBondContact O-N 3.28Å; A268-Q271 PolarHBondContact O-N 3.16Å
269A64Low77.5Confident30 Ų3089.8 Ų89.825%0.24850%0.5CS..THydrogen-bonded Turntrans-58.8-36.4-178.300000113.3S267S267-A269 WeakPolarHBondContact OG-CB 3.38Å; S267-A269 PolarHBondContact OG-N 3.14Å
270D59.5Low76.7Confident162 Ų16285.9 Ų85.987%0.86649%0.492SS*.THydrogen-bonded Turntrans-91.96.1-174.3-54.7-40.9000113.5A268A268-D270 VanDerWaalsContact C-N 3.25Å; A268-D270 PolarHBondContact O-N 3.28Å
271Q55.9Low76.2Confident131 Ų13181.2 Ų81.261%0.61248%0.478SS*.  trans-97.30179.3-68.5-173.5-2.700113.2A268A268-Q271 PolarHBondContact O-N 3.16Å

Retrieved 271 of 271 residues in 662.2 ms (Link to these results)