A0A087Y5V2_POEFO Loading...

SVOP-like

AlphaFold DB , UniProt , Accession A0A087Y5V2, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 562 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	27.7	Very low	26.2	Very low	226 Å²	226	167.8 Å²	167.8	100%	1.113	85%	0.849	S	S	*	*				0	127.2	0	-178.8	169.8	174.3	0	0	106.8
2	I	28.4	Very low	26.8	Very low	145 Å²	145	163.7 Å²	163.7	74%	0.744	84%	0.842	S	S	*	*			trans	66.2	99.2	-179	-55.9	161.8	0	0	0	112.6
3	L	25.7	Very low	26.8	Very low	148 Å²	148	162.8 Å²	162.8	78%	0.775	84%	0.84	S	S	*	*				57.3	105.8	63	-86.7	163.1	0	0	0	115	T5	L3-T5 HydrophobicContact CD2-CG2 4.48Å
4	L	27.2	Very low	26.8	Very low	174 Å²	174	158.6 Å²	158.6	91%	0.911	83%	0.832	S	S	*	*			trans	-153.1	125.4	139.8	-116.1	154.1	0	0	0	110.8
5	T	28.9	Very low	26.7	Very low	112 Å²	112	155.1 Å²	155.1	69%	0.687	83%	0.826	S	S	*	*			trans	-97.4	143.7	-176.3	44.4	0	0	0	0	111.4	L3	L3-T5 HydrophobicContact CD2-CG2 4.48Å
6	C	23.7	Very low	26.7	Very low	137 Å²	137	156.6 Å²	156.6	93%	0.926	83%	0.826	S	S	*	*			trans	-141.3	121.7	148.9	-102	0	0	0	0	110.2
7	R	25.6	Very low	26.6	Very low	237 Å²	237	161.8 Å²	161.8	89%	0.894	83%	0.832	S	S	*	*			trans	-118.8	174.2	170.3	-107.3	-170.6	178.6	-161.5	0.9	107.3
8	L	25.7	Very low	26.6	Very low	164 Å²	164	166.1 Å²	166.1	86%	0.859	84%	0.836	S	S	*	*			trans	86.6	131.6	178.1	-53.7	163.4	0	0	0	111.7
9	W	24.1	Very low	26.6	Very low	235 Å²	235	163.9 Å²	163.9	89%	0.89	83%	0.832	S	S	*	*			cis	-126.3	149.7	8.7	-101.8	7.1	0	0	0	109.8
10	A	24.5	Very low	26.6	Very low	80 Å²	80	165.3 Å²	165.3	66%	0.661	84%	0.835	S	S	*	*				78.1	99.3	53.5	0	0	0	0	0	114.4
11	E	27.1	Very low	26.8	Very low	188 Å²	188	165.5 Å²	165.5	88%	0.879	84%	0.837	S	S	*	*			trans	-75.1	163.8	158.8	-61.9	176.3	132.6	0	0	110
12	P	33	Very low	27.1	Very low	118 Å²	118	160.2 Å²	160.2	77%	0.766	82%	0.82	S	S	*	*				-148.8	160.6	97.9	38.1	-21.4	0	0	0	117.1
13	D	26.6	Very low	27.6	Very low	153 Å²	153	158.9 Å²	158.9	82%	0.818	82%	0.821	S	S	*	*			trans	23.1	133.1	150.7	-79.9	-47.9	0	0	0	122.4
14	S	26.6	Very low	28.6	Very low	103 Å²	103	157.4 Å²	157.4	72%	0.72	82%	0.82	S	S	*	*				170.5	137.5	93.8	48.5	0	0	0	0	116.9
15	S	25.7	Very low	28.7	Very low	106 Å²	106	154.4 Å²	154.4	74%	0.741	82%	0.82	S	S	*	*			trans	55	119.3	143	66.3	0	0	0	0	123.7
16	H	26.2	Very low	28.7	Very low	180 Å²	180	152.3 Å²	152.3	83%	0.833	82%	0.821	S	S	*	*			trans	16.7	127.9	139.6	-70.4	-50.1	0	0	0	122.1
17	R	26	Very low	28.8	Very low	244 Å²	244	150.6 Å²	150.6	92%	0.921	81%	0.811	S	S	*	*				-152.9	139.6	126.7	-134.5	168	-80	-152.8	-1.2	113.2
18	R	26.8	Very low	28.9	Very low	240 Å²	240	146.1 Å²	146.1	91%	0.906	81%	0.81	S	S	*	*			trans	-101	138.1	169.6	-71.3	179.3	178.7	172.1	-0.4	109.6
19	T	27.1	Very low	29.1	Very low	124 Å²	124	144.9 Å²	144.9	76%	0.761	80%	0.802	S	S	*	*			trans	-163.9	110.1	157.2	33.3	0	0	0	0	106.7
20	Q	26.2	Very low	29.2	Very low	192 Å²	192	140.3 Å²	140.3	90%	0.897	79%	0.794	S	S	*	*				66.5	112.4	80.7	-74.2	-173.5	-21.2	0	0	115.2
21	L	30.3	Very low	29.8	Very low	169 Å²	169	141.7 Å²	141.7	89%	0.885	80%	0.797	S	S	*	*			trans	-64.8	170.2	152	-81.3	111.5	0	0	0	110.2
22	P	35.1	Very low	29.7	Very low	116 Å²	116	139.1 Å²	139.1	75%	0.753	79%	0.789	S	S	*	*			cis	-144.2	-127.8	33.1	32.7	-3.4	0	0	0	116.2
23	P	38	Very low	29.5	Very low	116 Å²	116	139.1 Å²	139.1	75%	0.753	79%	0.787	S	S	*	*				-118.1	-140.1	-98.9	38.7	-17.8	0	0	0	116
24	P	46.9	Very low	29.9	Very low	118 Å²	118	137.8 Å²	137.8	77%	0.766	79%	0.787	S	S	*	*				-129.8	-164.8	-107.7	44.7	-24.9	0	0	0	117.1
25	A	29.3	Very low	29.9	Very low	110 Å²	110	140.4 Å²	140.4	91%	0.909	79%	0.787	S	S	*	*			trans	74.6	149.2	174.9	0	0	0	0	0	116.3
26	G	27.8	Very low	29.9	Very low	69 Å²	69	142.4 Å²	142.4	71%	0.711	79%	0.785	S	S	*	*			cis	177.4	-177.7	-2.1	0	0	0	0	0	109.5
27	S	27.5	Very low	30	Very low	101 Å²	101	139 Å²	139	71%	0.706	78%	0.777	S	S	*	*			cis	-179.9	118.3	-16.9	46.7	0	0	0	0	111.2
28	V	27.4	Very low	30	Very low	143 Å²	143	137.7 Å²	137.7	87%	0.867	77%	0.772	S	S	*	*			trans	-139.6	99.1	168.5	-173.8	0	0	0	0	107.2
29	I	28.6	Very low	29.9	Very low	138 Å²	138	137 Å²	137	71%	0.708	77%	0.769	S	S	*	*				64.9	125	70.9	-62	177.3	0	0	0	111.4
30	L	27.8	Very low	29.8	Very low	138 Å²	138	142.6 Å²	142.6	72%	0.723	78%	0.776	S	S	*	*			cis	-178.7	-172	-14.3	-107.1	162	0	0	0	104.5
31	P	35.8	Very low	29.8	Very low	109 Å²	109	138.3 Å²	138.3	71%	0.708	77%	0.767	S	S	*	*			cis	-110.5	166	-33.1	11.2	14.3	0	0	0	112
32	D	26	Very low	29.6	Very low	134 Å²	134	142.4 Å²	142.4	72%	0.717	77%	0.771	S	S	*	*				73.8	136.3	56.3	-129.3	6.7	0	0	0	111.9
33	V	28.4	Very low	29.2	Very low	119 Å²	119	141.2 Å²	141.2	72%	0.721	77%	0.771	S	S	*	*			cis	-154.8	-158.3	30.9	-142.3	0	0	0	0	112
34	P	34.3	Very low	28.5	Very low	125 Å²	125	145.1 Å²	145.1	81%	0.812	78%	0.776	S	S	*	*				-134.6	-142.7	-122.7	50.6	-29	0	0	0	117.8
35	E	27.8	Very low	27.4	Very low	157 Å²	157	147.3 Å²	147.3	73%	0.734	78%	0.781	S	S	*	*			trans	-67.2	159.9	-166.6	-88.7	-170.3	105.6	0	0	122.3
36	Q	25.6	Very low	27.1	Very low	149 Å²	149	150.3 Å²	150.3	70%	0.696	78%	0.776	S	S	*	*			trans	73	114.9	138.2	-76.7	-168.6	43.3	0	0	124.7
37	V	27.8	Very low	27.8	Very low	108 Å²	108	150.9 Å²	150.9	66%	0.655	77%	0.767	S	S	*	*				72.6	115.4	119.3	176.7	0	0	0	0	121.9
38	R	25.2	Very low	27.8	Very low	216 Å²	216	154.1 Å²	154.1	82%	0.815	77%	0.77	S	S	*	*			trans	104.9	113.7	139.3	-144.1	175.9	-74.7	-160.6	-1.3	121.3
39	R	26.2	Very low	27.6	Very low	225 Å²	225	152.1 Å²	152.1	85%	0.849	76%	0.762	S	S	*	*			trans	45.9	122.8	143.2	-66.9	-178.7	174.4	-174.5	-2.4	122.1
40	R	24.7	Very low	27.3	Very low	242 Å²	242	150.9 Å²	150.9	91%	0.913	76%	0.764	S	S	*	*				-147.8	128.8	123.6	-91.5	174.6	175.9	174.7	-2.6	106.1
41	S	25.4	Very low	27.2	Very low	102 Å²	102	153.5 Å²	153.5	71%	0.713	77%	0.772	S	S	*	*			cis	73.2	97.5	46.8	-56.1	0	0	0	0	114.3
42	R	26.2	Very low	26.8	Very low	255 Å²	255	155.5 Å²	155.5	96%	0.962	78%	0.776	S	S	*	*			trans	-138.3	122.9	144.2	-82.9	-169.5	177.6	176.8	0.1	108.7
43	A	26	Very low	26.7	Very low	91 Å²	91	157.3 Å²	157.3	75%	0.752	77%	0.773	S	S	*	*			trans	-102.5	162.3	161.8	0	0	0	0	0	108.1
44	F	24.5	Very low	26.5	Very low	198 Å²	198	160.6 Å²	160.6	87%	0.868	78%	0.78	S	S	*	*				-173.5	150.1	128.4	-115.2	-75.4	0	0	0	113.4
45	L	24.3	Very low	26.2	Very low	164 Å²	164	160.3 Å²	160.3	86%	0.859	77%	0.768	S	S	*	*			trans	81.5	128.4	159.7	-82.2	135.6	0	0	0	121.7
46	H	22.7	Very low	26.1	Very low	174 Å²	174	161.1 Å²	161.1	81%	0.806	78%	0.777	S	S	*	*			trans	-118.4	-161.2	175.7	-137.1	-27.1	0	0	0	104.7
47	P	42.7	Very low	26	Very low	81 Å²	81	159 Å²	159	53%	0.526	79%	0.785	S	S	.	*			cis	-138.3	-171.2	-21.3	25.6	0.7	0	0	0	114.6
48	H	26.2	Very low	25.9	Very low	168 Å²	168	158.6 Å²	158.6	78%	0.778	79%	0.794	S	S	*	*			trans	70.9	152.5	158.5	-62	-55.7	0	0	0	119.6
49	C	23.7	Very low	26	Very low	101 Å²	101	157.9 Å²	157.9	68%	0.682	80%	0.8	S	S	*	*			cis	-159.8	164.9	-12.8	-123	0	0	0	0	112.7
50	C	23	Very low	25.9	Very low	112 Å²	112	154.5 Å²	154.5	76%	0.757	80%	0.798	S	S	*	*			trans	46.2	121.2	151.1	-64	0	0	0	0	122.8
51	H	25.9	Very low	26	Very low	193 Å²	193	151.6 Å²	151.6	89%	0.894	80%	0.795	S	S	*	*				-153.7	127.6	116.4	-122.8	-76.2	0	0	0	114
52	L	25.4	Very low	25.9	Very low	152 Å²	152	158 Å²	158	80%	0.796	80%	0.804	S	S	*	*			trans	-80.7	163	158.6	-84.8	153.9	0	0	0	108.1
53	R	23.9	Very low	25.9	Very low	171 Å²	171	151.9 Å²	151.9	65%	0.645	80%	0.799	S	S	*	*			cis	-172.5	150.5	2	159.9	-172.9	-169.2	165.2	8	105.9	E55	R53-E55 IonicContact CZ-OE1 3.43Å; R53-E55 IonicContact CZ-OE2 3.74Å; R53-E55 IonicContact NE-OE1 3.74Å; R53-E55 PolarHBondContact NE-OE1 3.42Å; R53-E55 IonicContact NE-OE2 3.91Å; R53-E55 PolarHBondContact NE-OE2 2.71Å; R53-E55 IonicContact NH2-OE1 3.73Å; R53-E55 PolarHBondContact NH2-OE1 2.8Å; R53-E55 IonicContact NH2-OE2 2.71Å; R53-E55 PolarHBondContact NH2-OE2 3.49Å
54	H	25.7	Very low	25.9	Very low	188 Å²	188	151.4 Å²	151.4	87%	0.87	80%	0.796	S	S	*	*			trans	-160.5	128.3	140.8	-116.5	-72.5	0	0	0	111.2
55	E	27.2	Very low	26	Very low	119 Å²	119	147.9 Å²	147.9	56%	0.556	79%	0.793	S	S	*	*			trans	-75.1	148.1	175.3	-72	117.7	137.2	0	0	112.4	R53	R53-E55 IonicContact CZ-OE1 3.43Å; R53-E55 IonicContact CZ-OE2 3.74Å; R53-E55 IonicContact NE-OE1 3.74Å; R53-E55 PolarHBondContact NE-OE1 3.42Å; R53-E55 IonicContact NE-OE2 3.91Å; R53-E55 PolarHBondContact NE-OE2 2.71Å; R53-E55 IonicContact NH2-OE1 3.73Å; R53-E55 PolarHBondContact NH2-OE1 2.8Å; R53-E55 IonicContact NH2-OE2 2.71Å; R53-E55 PolarHBondContact NH2-OE2 3.49Å
56	N	25.4	Very low	26.3	Very low	174 Å²	174	146.5 Å²	146.5	93%	0.93	79%	0.791	S	S	*	*			trans	-152	138.1	132.5	-100.9	-25.7	0	0	0	109.2
57	A	24.8	Very low	26.7	Very low	104 Å²	104	141.7 Å²	141.7	86%	0.86	78%	0.777	S	S	*	*			trans	-98.3	141.5	-169.4	0	0	0	0	0	112.5
58	A	25.6	Very low	26.2	Very low	101 Å²	101	145.6 Å²	145.6	84%	0.835	79%	0.788	S	S	*	*			trans	-153.1	117	151.5	0	0	0	0	0	107.5
59	E	26	Very low	26.5	Very low	201 Å²	201	146 Å²	146	94%	0.939	79%	0.793	S	S	*	*			trans	-75.9	129.8	169.4	-70	176.2	108.7	0	0	109.2
60	D	24.5	Very low	27.3	Very low	153 Å²	153	145.2 Å²	145.2	82%	0.818	79%	0.785	S	S	*	*			trans	-147.3	163.8	152.2	-148.3	-11.6	0	0	0	111
61	Q	26.6	Very low	28	Very low	181 Å²	181	143.8 Å²	143.8	85%	0.846	77%	0.77	S	S	*	*			trans	-92.6	165	-144.1	-62.4	177.7	3.5	0	0	116.1
62	R	24.6	Very low	28.5	Very low	238 Å²	238	137.9 Å²	137.9	90%	0.898	75%	0.751	S	S	*	*			trans	-51.4	146.4	178	-57.5	165.2	174.4	177.1	-2.7	113.7
63	S	25.8	Very low	29.2	Very low	125 Å²	125	137.3 Å²	137.3	87%	0.874	75%	0.746	S	S	*	*				164.4	165	104.9	54.4	0	0	0	0	113.4
64	A	25.1	Very low	30.1	Very low	82 Å²	82	135.1 Å²	135.1	68%	0.678	74%	0.74	S	S	*	*			trans	-100.7	150.8	-174.1	0	0	0	0	0	112.8	T66	A64-T66 PolarHBondContact O-N 3.38Å
65	P	26.8	Very low	30.7	Very low	123 Å²	123	130.8 Å²	130.8	80%	0.799	73%	0.727	S	S	*	*	S	Bend	trans	-89.6	96.1	-170.7	34.1	-34.6	0	0	0	113.4
66	T	31.1	Very low	31.4	Very low	135 Å²	135	131.4 Å²	131.4	83%	0.828	73%	0.73	S	S	*	*			trans	-143.6	4.6	170.8	47.4	0	0	0	0	116.5	A64	A64-T66 PolarHBondContact O-N 3.38Å
67	S	31.4	Very low	32	Very low	73 Å²	73	128.6 Å²	128.6	51%	0.51	72%	0.715	S	S	.	*	S	Bend	trans	-99.8	-30.9	-175.9	51.4	0	0	0	0	116	M69 T70 D71	S67-M69 PolarHBondContact O-N 3.31Å; S67-T70 PolarHBondContact O-N 2.96Å; S67-T70 PolarHBondContact O-OG1 3.47Å; S67-D71 PolarHBondContact O-N 3.39Å
68	E	31.9	Very low	32.9	Very low	163 Å²	163	128.4 Å²	128.4	76%	0.762	70%	0.703	S	S	*	*	H	α-helix	trans	-65.3	-35.8	-164.7	-63.9	-175.7	136.5	0	0	114.4	T70 D71 S72	E68-T70 PolarHBondContact O-N 2.89Å; E68-D71 PolarHBondContact O-N 2.8Å; E68-S72 PolarHBondContact O-N 2.94Å
69	M	31.3	Very low	33.4	Very low	176 Å²	176	126.9 Å²	126.9	87%	0.867	69%	0.686	S	S	*	*	H	α-helix	trans	-67.9	-23.9	-178.6	-163.3	170.8	71	0	0	112.9	S67	S67-M69 PolarHBondContact O-N 3.31Å
70	T	42	Very low	34.1	Very low	86 Å²	86	119.7 Å²	119.7	53%	0.528	66%	0.661	S	S	.	*	H	α-helix	trans	-83.9	-32.3	175.6	22.5	0	0	0	0	113.8	S67 E68 K74	S67-T70 PolarHBondContact O-N 2.96Å; S67-T70 PolarHBondContact O-OG1 3.47Å; E68-T70 PolarHBondContact O-N 2.89Å; T70-K74 PolarHBondContact O-N 3.47Å
71	D	37.8	Very low	35	Very low	81 Å²	81	117 Å²	117	43%	0.433	65%	0.646	S	S	.	*	H	α-helix	trans	-80.1	-33.7	179.9	-86.2	-9.8	0	0	0	112.3	S67 E68 M73 K74 T75	S67-D71 PolarHBondContact O-N 3.39Å; E68-D71 PolarHBondContact O-N 2.8Å; D71-M73 PolarHBondContact O-N 3.42Å; D71-K74 PolarHBondContact O-N 3.22Å; D71-K74 WeakPolarHBondContact OD1-CD 3.49Å; D71-K74 IonicContact OD1-NZ 2.84Å; D71-K74 PolarHBondContact OD1-NZ 3.48Å; D71-K74 VanDerWaalsContact OD1-NZ 3.14Å; D71-T75 PolarHBondContact O-N 3.11Å; D71-T75 PolarHBondContact O-OG1 3.47Å
72	S	36.1	Very low	35.2	Very low	70 Å²	70	114.7 Å²	114.7	49%	0.49	63%	0.634	S	S	.	*	H	α-helix	trans	-52.8	-42.5	171.1	-174.2	0	0	0	0	112	E68 T75 Q76	E68-S72 PolarHBondContact O-N 2.94Å; S72-T75 PolarHBondContact O-N 2.92Å; S72-Q76 WeakPolarHBondContact O-CG 3.44Å; S72-Q76 PolarHBondContact O-N 2.8Å; S72-Q76 VanDerWaalsContact O-N 3.11Å
73	M	40	Very low	36	Very low	140 Å²	140	108.7 Å²	108.7	69%	0.69	62%	0.62	S	S	*	*	H	α-helix	trans	-72.2	-32.1	178.9	-148.1	177.6	81.1	0	0	113	D71 L77	D71-M73 PolarHBondContact O-N 3.42Å; M73-L77 WeakPolarHBondContact O-CB 3.44Å; M73-L77 PolarHBondContact O-N 3.32Å; M73-L77 VanDerWaalsContact O-N 3.12Å
74	K	41.6	Very low	36.5	Very low	124 Å²	124	108.9 Å²	108.9	54%	0.539	61%	0.607	S	S	.	*	H	α-helix	trans	-71	-41.3	172.3	-74.7	179.1	-168.9	157.4	0	112.3	T70 D71 Q76 L77 V78	T70-K74 PolarHBondContact O-N 3.47Å; D71-K74 PolarHBondContact O-N 3.22Å; D71-K74 WeakPolarHBondContact OD1-CD 3.49Å; D71-K74 IonicContact OD1-NZ 2.84Å; D71-K74 PolarHBondContact OD1-NZ 3.48Å; D71-K74 VanDerWaalsContact OD1-NZ 3.14Å; K74-Q76 VanDerWaalsContact C-N 3.32Å; K74-Q76 PolarHBondContact O-N 3.22Å; K74-L77 WeakPolarHBondContact O-CB 3.25Å; K74-L77 PolarHBondContact O-N 3.17Å; K74-L77 VanDerWaalsContact O-N 3.1Å; K74-V78 WeakPolarHBondContact O-CG2 3.5Å; K74-V78 PolarHBondContact O-N 3.03Å
75	T	39.9	Very low	37.1	Very low	97 Å²	97	110.2 Å²	110.2	60%	0.595	60%	0.599	S	S	*	*	H	α-helix	trans	-65.1	-38.5	179.5	-54.5	0	0	0	0	110.8	D71 S72 S79	D71-T75 PolarHBondContact O-N 3.11Å; D71-T75 PolarHBondContact O-OG1 3.47Å; S72-T75 PolarHBondContact O-N 2.92Å; T75-S79 WeakPolarHBondContact O-CB 3.4Å; T75-S79 PolarHBondContact O-N 3.02Å
76	Q	40.4	Very low	37.5	Very low	133 Å²	133	108.6 Å²	108.6	62%	0.621	59%	0.587	S	S	*	*	H	α-helix	trans	-62.5	-41.7	169.2	-73.8	-178.3	-13.5	0	0	112.3	S72 K74 S79 A80	S72-Q76 WeakPolarHBondContact O-CG 3.44Å; S72-Q76 PolarHBondContact O-N 2.8Å; S72-Q76 VanDerWaalsContact O-N 3.11Å; K74-Q76 VanDerWaalsContact C-N 3.32Å; K74-Q76 PolarHBondContact O-N 3.22Å; Q76-S79 PolarHBondContact O-N 3.28Å; Q76-A80 WeakPolarHBondContact O-CB 3.38Å; Q76-A80 PolarHBondContact O-N 2.77Å
77	L	38.6	Very low	37.7	Very low	114 Å²	114	109.8 Å²	109.8	60%	0.597	58%	0.583	S	S	*	*	H	α-helix	trans	-63.9	-41.6	178.1	-161	75.5	0	0	0	112.7	M73 K74 A80 I81	M73-L77 WeakPolarHBondContact O-CB 3.44Å; M73-L77 PolarHBondContact O-N 3.32Å; M73-L77 VanDerWaalsContact O-N 3.12Å; K74-L77 WeakPolarHBondContact O-CB 3.25Å; K74-L77 PolarHBondContact O-N 3.17Å; K74-L77 VanDerWaalsContact O-N 3.1Å; L77-A80 PolarHBondContact O-N 3.28Å; L77-I81 WeakPolarHBondContact O-CG1 3.45Å; L77-I81 PolarHBondContact O-N 3.32Å; L77-I81 VanDerWaalsContact O-N 3.15Å
78	V	43.4	Very low	37.8	Very low	100 Å²	100	114 Å²	114	61%	0.606	60%	0.596	S	S	*	*	H	α-helix	trans	-69.5	-38.7	177.7	174.1	0	0	0	0	111.5	K74 I81 H82	K74-V78 WeakPolarHBondContact O-CG2 3.5Å; K74-V78 PolarHBondContact O-N 3.03Å; V78-I81 PolarHBondContact O-N 3.33Å; V78-H82 PolarHBondContact O-N 3.29Å
79	S	37.3	Very low	37.6	Very low	69 Å²	69	114.4 Å²	114.4	48%	0.483	60%	0.598	S	S	.	*	H	α-helix	trans	-63.5	-40.4	174.5	-178.8	0	0	0	0	112.2	T75 Q76 H82 L83	T75-S79 WeakPolarHBondContact O-CB 3.4Å; T75-S79 PolarHBondContact O-N 3.02Å; Q76-S79 PolarHBondContact O-N 3.28Å; S79-H82 PolarHBondContact O-N 2.99Å; S79-L83 PolarHBondContact O-N 3.25Å; S79-L83 VanDerWaalsContact O-N 3.15Å
80	A	40.2	Very low	37.5	Very low	51 Å²	51	113.9 Å²	113.9	42%	0.421	59%	0.594	S	S	.	*	H	α-helix	trans	-64.1	-40.7	176	0	0	0	0	0	112.8	Q76 L77 H82 L83 Q84	Q76-A80 WeakPolarHBondContact O-CB 3.38Å; Q76-A80 PolarHBondContact O-N 2.77Å; L77-A80 PolarHBondContact O-N 3.28Å; A80-H82 PolarHBondContact O-N 3.41Å; A80-L83 PolarHBondContact O-N 2.92Å; A80-Q84 WeakPolarHBondContact O-CB 3.38Å; A80-Q84 PolarHBondContact O-N 3.07Å
81	I	42.1	Very low	36.7	Very low	96 Å²	96	118.5 Å²	118.5	49%	0.492	61%	0.607	S	S	.	*	H	α-helix	trans	-60	-36.5	175.9	-70.1	163.6	0	0	0	111.2	L77 V78 Q84 Q85	L77-I81 WeakPolarHBondContact O-CG1 3.45Å; L77-I81 PolarHBondContact O-N 3.32Å; L77-I81 VanDerWaalsContact O-N 3.15Å; V78-I81 PolarHBondContact O-N 3.33Å; I81-Q84 PolarHBondContact O-N 3.46Å; I81-Q85 PolarHBondContact O-N 3.45Å
82	H	31.2	Very low	36.4	Very low	132 Å²	132	120.4 Å²	120.4	61%	0.611	62%	0.623	S	S	*	*	H	α-helix	trans	-74.4	-40.2	-179.6	-139.6	19.1	0	0	0	112.3	V78 S79 A80 Q84 Q85 V86	V78-H82 PolarHBondContact O-N 3.29Å; S79-H82 PolarHBondContact O-N 2.99Å; A80-H82 PolarHBondContact O-N 3.41Å; H82-Q84 VanDerWaalsContact C-N 3.3Å; H82-Q84 PolarHBondContact O-N 2.87Å; H82-Q85 PolarHBondContact ND1-OE1 3.25Å; H82-Q85 PolarHBondContact O-N 2.8Å; H82-V86 PolarHBondContact O-N 3.42Å
83	L	41.9	Very low	36.3	Very low	113 Å²	113	124 Å²	124	59%	0.592	64%	0.642	S	S	*	*	H	α-helix	trans	-58.7	-40.9	170.7	-88.3	157.6	0	0	0	112.2	S79 A80 Q85 V86 E87	S79-L83 PolarHBondContact O-N 3.25Å; S79-L83 VanDerWaalsContact O-N 3.15Å; A80-L83 PolarHBondContact O-N 2.92Å; L83-Q85 VanDerWaalsContact C-N 3.26Å; L83-Q85 PolarHBondContact O-N 3.1Å; L83-V86 WeakPolarHBondContact O-CB 3.44Å; L83-V86 PolarHBondContact O-N 3.17Å; L83-V86 VanDerWaalsContact O-N 3.07Å; L83-E87 PolarHBondContact O-N 3.22Å
84	Q	36.7	Very low	35.7	Very low	129 Å²	129	119.9 Å²	119.9	60%	0.603	64%	0.636	S	S	*	*	H	α-helix	trans	-71.6	-17.6	-179.2	-157.3	164.6	18.9	0	0	113.6	A80 I81 H82	A80-Q84 WeakPolarHBondContact O-CB 3.38Å; A80-Q84 PolarHBondContact O-N 3.07Å; I81-Q84 PolarHBondContact O-N 3.46Å; H82-Q84 VanDerWaalsContact C-N 3.3Å; H82-Q84 PolarHBondContact O-N 2.87Å
85	Q	36.3	Very low	35.6	Very low	110 Å²	110	122.7 Å²	122.7	51%	0.514	66%	0.657	S	S	.	*	H	α-helix	trans	-78.2	-32.9	167.5	-74.1	-179.1	-50	0	0	112.5	I81 H82 L83 M88	I81-Q85 PolarHBondContact O-N 3.45Å; H82-Q85 PolarHBondContact ND1-OE1 3.25Å; H82-Q85 PolarHBondContact O-N 2.8Å; L83-Q85 VanDerWaalsContact C-N 3.26Å; L83-Q85 PolarHBondContact O-N 3.1Å; Q85-M88 PolarHBondContact O-N 3.17Å
86	V	35.8	Very low	35.2	Very low	89 Å²	89	123.2 Å²	123.2	54%	0.539	67%	0.665	S	S	.	*	H	α-helix	trans	-68	-43.5	177.2	177.9	0	0	0	0	110.8	H82 L83 M88 Q89	H82-V86 PolarHBondContact O-N 3.42Å; L83-V86 WeakPolarHBondContact O-CB 3.44Å; L83-V86 PolarHBondContact O-N 3.17Å; L83-V86 VanDerWaalsContact O-N 3.07Å; V86-M88 PolarHBondContact O-N 3.43Å; V86-Q89 PolarHBondContact O-N 2.88Å
87	E	34.7	Very low	35.3	Very low	159 Å²	159	126.9 Å²	126.9	74%	0.743	68%	0.682	S	S	*	*	T	Hydrogen-bonded Turn	trans	-63.6	-20.7	178	-71	-173.3	150.1	0	0	114.2	L83	L83-E87 PolarHBondContact O-N 3.22Å
88	M	34.1	Very low	35.2	Very low	162 Å²	162	124.3 Å²	124.3	80%	0.798	68%	0.682	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85.6	-6.8	174.4	-73.9	-155.8	-60.1	0	0	114.5	Q85 V86	Q85-M88 PolarHBondContact O-N 3.17Å; V86-M88 PolarHBondContact O-N 3.43Å
89	Q	27.2	Very low	34.9	Very low	172 Å²	172	126.7 Å²	126.7	80%	0.804	69%	0.692	S	S	*	*	T	Hydrogen-bonded Turn	trans	-103.7	-21.6	179.9	-80.5	-167.4	-48	0	0	115	V86 K91	V86-Q89 PolarHBondContact O-N 2.88Å; Q89-K91 PolarHBondContact O-N 2.8Å
90	E	30.3	Very low	35.4	Very low	164 Å²	164	129.8 Å²	129.8	77%	0.766	70%	0.703	S	S	*	*			trans	-81.4	86.4	173.8	-74.6	-161.1	140.4	0	0	112.2	P92	E90-P92 WeakPolarHBondContact O-CD 3.34Å
91	K	26	Very low	35.9	Very low	184 Å²	184	131.1 Å²	131.1	80%	0.8	71%	0.714	S	S	*	*			trans	-93.8	106.7	160	-165.6	-179	-169.7	-178.7	0	108.1	Q89 T93	Q89-K91 PolarHBondContact O-N 2.8Å; K91-T93 PolarHBondContact O-N 3.34Å
92	P	29.6	Very low	36.8	Very low	121 Å²	121	132.7 Å²	132.7	79%	0.786	72%	0.723	S	S	*	*			trans	-71.8	98.4	-176.9	-15.3	30.5	0	0	0	110.6	E90 G94	E90-P92 WeakPolarHBondContact O-CD 3.34Å; P92-G94 PolarHBondContact O-N 3.14Å
93	T	35.5	Very low	39.1	Very low	145 Å²	145	130.8 Å²	130.8	89%	0.89	72%	0.715	S	S	*	*			trans	-74.3	83.7	159.7	44.8	0	0	0	0	108.4	K91	K91-T93 PolarHBondContact O-N 3.34Å
94	G	27.7	Very low	41.2	Very low	54 Å²	54	132 Å²	132	56%	0.557	72%	0.716	S	S	*	*			trans	-146.5	114.8	179.4	0	0	0	0	0	111.3	P92 S96	P92-G94 PolarHBondContact O-N 3.14Å; G94-S96 PolarHBondContact O-N 3.04Å
95	N	38.4	Very low	43.6	Very low	183 Å²	183	126.6 Å²	126.6	98%	0.979	69%	0.69	S	S	*	*			trans	-61.5	117.7	171.3	-100.8	-12.2	0	0	0	110
96	S	32	Very low	46	Very low	108 Å²	108	123 Å²	123	76%	0.755	68%	0.675	S	S	*	*			trans	-138.6	85	171.1	41.7	0	0	0	0	110.9	G94 G98	G94-S96 PolarHBondContact O-N 3.04Å; S96-G98 PolarHBondContact O-N 3.35Å
97	Q	41.8	Very low	48.3	Very low	210 Å²	210	118.8 Å²	118.8	98%	0.981	65%	0.65	S	S	*	*			trans	-71.5	103.2	157.6	-75.5	-179.4	-27.5	0	0	108.2
98	G	36.4	Very low	50.6	Low	59 Å²	59	114.9 Å²	114.9	61%	0.608	63%	0.632	S	S	*	*			trans	169.4	115.3	174.2	0	0	0	0	0	114.8	S96	S96-G98 PolarHBondContact O-N 3.35Å
99	N	37.5	Very low	52.9	Low	151 Å²	151	111.7 Å²	111.7	81%	0.807	62%	0.615	S	S	*	*			trans	64.9	76.3	164.6	-62.5	-10	0	0	0	118.9	A101	N99-A101 PolarHBondContact O-N 3.5Å
100	N	48.8	Very low	55.7	Low	133 Å²	133	103.5 Å²	103.5	71%	0.711	58%	0.577	S	S	*	*	T	Hydrogen-bonded Turn	trans	-66.4	26.4	161.9	-66.1	3.2	0	0	0	114.3
101	A	50.8	Low	58.4	Low	80 Å²	80	96.1 Å²	96.1	66%	0.661	54%	0.543	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.5	-22.7	-170	0	0	0	0	0	114.2	N99	N99-A101 PolarHBondContact O-N 3.5Å
102	D	60.4	Low	61.3	Low	128 Å²	128	92.4 Å²	92.4	68%	0.684	53%	0.528	S	S	*	.	S	Bend	trans	-114.2	3.1	-170	-99.8	-49	0	0	0	115.2	K104	D102-K104 PolarHBondContact O-N 3Å
103	E	80.1	Confident	64	Low	93 Å²	93	90.5 Å²	90.5	44%	0.435	52%	0.515	S	S	.	.			trans	-58.7	139.3	171.2	-68.8	-174.2	132.7	0	0	110.1	P328 G329 R330	E103-P328 WeakPolarHBondContact OE2-CB 3.31Å; E103-P328 WeakPolarHBondContact OE2-CG 3.45Å; E103-G329 CarbonylContact O-C 3.58Å; E103-G329 WeakPolarHBondContact O-CA 3.39Å; E103-R330 PolarHBondContact O-N 2.86Å
104	K	86	Confident	66.6	Low	139 Å²	139	84 Å²	84	60%	0.604	47%	0.474	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-129.6	134.4	-177.5	-70.8	162.6	-166.4	160.7	0	108.9	D102 R330 V332	D102-K104 PolarHBondContact O-N 3Å; K104-R330 WeakPolarHBondContact CA-O 3.24Å; K104-V332 HydrophobicContact CB-CB 4.45Å; K104-V332 HydrophobicContact CD-CG2 4.39Å; K104-V332 HydrophobicContact CG-CB 4.45Å; K104-V332 HydrophobicContact CG-CG2 4.06Å
105	F	85.9	Confident	69.4	Low	14 Å²	14	82.3 Å²	82.3	6%	0.061	46%	0.457	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.8	151.6	176.7	68.3	-97.8	0	0	0	111.7	Q109 A110 L326 P327 P328 G329 R330 L331 V332	F105-Q109 VanDerWaalsContact CA-OE1 3.31Å; F105-A110 HydrophobicContact CD2-CB 3.85Å; F105-A110 HydrophobicContact CE2-CB 3.8Å; F105-L326 HydrophobicContact CE2-CD2 4.23Å; F105-L326 HydrophobicContact CZ-CD2 4.2Å; F105-P327 HydrophobicContact CB-CB 4.02Å; F105-P327 HydrophobicContact CB-CG 4.31Å; F105-P327 HydrophobicContact CD1-CB 3.97Å; F105-P327 HydrophobicContact CD2-CG 4.24Å; F105-P327 WeakPolarHBondContact CE1-O 3.36Å; F105-P327 HydrophobicContact CG-CB 3.94Å; F105-P327 HydrophobicContact CG-CG 4.14Å; F105-P328 WeakPolarHBondContact CD1-O 3.38Å; F105-G329 WeakPolarHBondContact CE1-O 3.17Å; F105-R330 PolarHBondContact N-O 3.37Å; F105-L331 HydrophobicContact CD2-CD1 3.9Å; F105-L331 HydrophobicContact CE2-CB 3.94Å; F105-L331 HydrophobicContact CE2-CD1 3.71Å; F105-L331 HydrophobicContact CE2-CG 4.38Å; F105-L331 HydrophobicContact CZ-CB 4.04Å; F105-L331 WeakPolarHBondContact O-CA 3.19Å; F105-V332 PolarHBondContact O-N 3.35Å
106	T	86.7	Confident	71.9	Confident	34 Å²	34	77.1 Å²	77.1	21%	0.209	43%	0.426	C	S	.	.			trans	-93.9	164.9	176.5	69.6	0	0	0	0	111.9	E108 Q109 A110	T106-E108 PolarHBondContact O-N 2.85Å; T106-Q109 PolarHBondContact O-N 2.95Å; T106-Q109 WeakPolarHBondContact OG1-CG 3.48Å; T106-Q109 PolarHBondContact OG1-N 3.06Å; T106-Q109 PolarHBondContact OG1-OE1 2.82Å; T106-A110 PolarHBondContact O-N 3.11Å
107	V	84.1	Confident	74.7	Confident	1 Å²	1	72.8 Å²	72.8	1%	0.006	40%	0.398	C	S	.	.	H	α-helix	trans	-59.9	-34.5	174.1	-177.1	0	0	0	0	111.1	V111 A299 R300 V303 L331 E333	V107-V111 HydrophobicContact CG1-CG2 4.47Å; V107-V111 VanDerWaalsContact O-CG2 3.31Å; V107-V111 WeakPolarHBondContact O-CG2 3.5Å; V107-V111 PolarHBondContact O-N 3.04Å; V107-A299 HydrophobicContact CG1-CB 3.78Å; V107-R300 HydrophobicContact CB-CG 4.26Å; V107-R300 HydrophobicContact CG1-CG 3.66Å; V107-V303 HydrophobicContact CG2-CB 4.47Å; V107-V303 HydrophobicContact CG2-CG2 3.74Å; V107-L331 HydrophobicContact CG2-CD1 3.81Å; V107-L331 HydrophobicContact CG2-CD2 4.44Å; V107-E333 WeakPolarHBondContact CG2-OE2 3.36Å
108	E	82.7	Confident	77.1	Confident	78 Å²	78	70.3 Å²	70.3	36%	0.364	38%	0.38	S	S	.	.	H	α-helix	trans	-66.9	-49.8	178	-168.7	140.4	-108.7	0	0	111.6	T106 A110 V111 E112 R300	T106-E108 PolarHBondContact O-N 2.85Å; E108-A110 VanDerWaalsContact C-N 3.31Å; E108-A110 PolarHBondContact O-N 3.18Å; E108-V111 PolarHBondContact O-N 3.11Å; E108-V111 VanDerWaalsContact O-N 3.17Å; E108-E112 WeakPolarHBondContact O-CG 3.19Å; E108-E112 PolarHBondContact O-N 3.23Å; E108-R300 IonicContact OE1-CZ 3.52Å; E108-R300 IonicContact OE1-NH1 3.49Å; E108-R300 IonicContact OE1-NH2 2.71Å; E108-R300 PolarHBondContact OE1-NH2 3.19Å
109	Q	83.9	Confident	79.8	Confident	95 Å²	95	67.7 Å²	67.7	44%	0.444	35%	0.352	S	S	.	.	H	α-helix	trans	-56.9	-44.2	174.2	-73.4	167.4	-29.6	0	0	111.7	F105 T106 V111 E112 T113	F105-Q109 VanDerWaalsContact CA-OE1 3.31Å; T106-Q109 PolarHBondContact O-N 2.95Å; T106-Q109 WeakPolarHBondContact OG1-CG 3.48Å; T106-Q109 PolarHBondContact OG1-N 3.06Å; T106-Q109 PolarHBondContact OG1-OE1 2.82Å; Q109-V111 PolarHBondContact O-N 3.47Å; Q109-E112 PolarHBondContact O-N 3.25Å; Q109-T113 WeakPolarHBondContact O-CB 3.26Å; Q109-T113 PolarHBondContact O-N 3.41Å; Q109-T113 PolarHBondContact O-OG1 3.18Å
110	A	85.9	Confident	82.3	Confident	0 Å²	0	60.7 Å²	60.7	0%	0	31%	0.314	C	S	.	.	H	α-helix	trans	-61	-42.9	177.3	0	0	0	0	0	112.9	F105 T106 E108 E112 I114 L315 L326 P327	F105-A110 HydrophobicContact CD2-CB 3.85Å; F105-A110 HydrophobicContact CE2-CB 3.8Å; T106-A110 PolarHBondContact O-N 3.11Å; E108-A110 VanDerWaalsContact C-N 3.31Å; E108-A110 PolarHBondContact O-N 3.18Å; A110-E112 VanDerWaalsContact C-N 3.34Å; A110-I114 VanDerWaalsContact O-CB 3.3Å; A110-I114 WeakPolarHBondContact O-CB 3.47Å; A110-I114 WeakPolarHBondContact O-CD1 3.28Å; A110-I114 WeakPolarHBondContact O-CG1 3.36Å; A110-I114 PolarHBondContact O-N 2.93Å; A110-L315 HydrophobicContact CB-CD1 3.9Å; A110-L315 HydrophobicContact CB-CD2 4.32Å; A110-L326 HydrophobicContact CB-CD2 4.05Å; A110-P327 HydrophobicContact CB-CG 4.37Å
111	V	86.5	Confident	84.4	Confident	9 Å²	9	57.8 Å²	57.8	6%	0.055	30%	0.301	C	S	.	.	H	α-helix	trans	-66.4	-36.8	177.2	167.7	0	0	0	0	111.4	V107 E108 Q109 G115 F237 P239 L315	V107-V111 HydrophobicContact CG1-CG2 4.47Å; V107-V111 VanDerWaalsContact O-CG2 3.31Å; V107-V111 WeakPolarHBondContact O-CG2 3.5Å; V107-V111 PolarHBondContact O-N 3.04Å; E108-V111 PolarHBondContact O-N 3.11Å; E108-V111 VanDerWaalsContact O-N 3.17Å; Q109-V111 PolarHBondContact O-N 3.47Å; V111-G115 PolarHBondContact O-N 3.15Å; V111-F237 WeakPolarHBondContact CG1-O 3.28Å; V111-P239 HydrophobicContact CG1-CB 4.16Å; V111-P239 HydrophobicContact CG1-CG 3.84Å; V111-L315 HydrophobicContact CG2-CD2 4.08Å
112	E	86.3	Confident	86.3	Confident	105 Å²	105	57 Å²	57	49%	0.491	29%	0.286	S	S	.	.	H	α-helix	trans	-71	-43.3	176.7	-68.8	-168.6	155.4	0	0	112.8	E108 Q109 A110 G115	E108-E112 WeakPolarHBondContact O-CG 3.19Å; E108-E112 PolarHBondContact O-N 3.23Å; Q109-E112 PolarHBondContact O-N 3.25Å; A110-E112 VanDerWaalsContact C-N 3.34Å; E112-G115 PolarHBondContact O-N 3.26Å
113	T	87.2	Confident	87.8	Confident	82 Å²	82	51.1 Å²	51.1	50%	0.503	25%	0.254	S	S	.	.	H	α-helix	trans	-65.2	-39	175.4	-56.1	0	0	0	0	112.6	Q109 G115 P327	Q109-T113 WeakPolarHBondContact O-CB 3.26Å; Q109-T113 PolarHBondContact O-N 3.41Å; Q109-T113 PolarHBondContact O-OG1 3.18Å; T113-G115 VanDerWaalsContact C-N 3.25Å; T113-G115 PolarHBondContact O-N 3.03Å; T113-P327 HydrophobicContact CG2-CG 4.18Å
114	I	89.6	Confident	88.3	Confident	8 Å²	8	48.2 Å²	48.2	4%	0.041	24%	0.24	C	C	.	.	H	α-helix	trans	-66.8	-29.1	175.6	-71.7	166.1	0	0	0	111.7	A110 L315 I318 A319 N322 A324 L326	A110-I114 VanDerWaalsContact O-CB 3.3Å; A110-I114 WeakPolarHBondContact O-CB 3.47Å; A110-I114 WeakPolarHBondContact O-CD1 3.28Å; A110-I114 WeakPolarHBondContact O-CG1 3.36Å; A110-I114 PolarHBondContact O-N 2.93Å; I114-L315 HydrophobicContact CD1-CB 4.34Å; I114-L315 HydrophobicContact CD1-CD2 4.43Å; I114-I318 HydrophobicContact CG2-CG2 3.85Å; I114-A319 HydrophobicContact CD1-CB 3.92Å; I114-A319 HydrophobicContact CG1-CB 3.95Å; I114-N322 HydrophobicContact CG2-CB 4.24Å; I114-N322 WeakPolarHBondContact CG2-ND2 3.19Å; I114-A324 HydrophobicContact CG2-CB 4.37Å; I114-L326 HydrophobicContact CD1-CD2 4.07Å
115	G	87.3	Confident	88.5	Confident	19 Å²	19	45.2 Å²	45.2	20%	0.196	23%	0.233	C	C	.	.			trans	66.4	180	174.4	0	0	0	0	0	115.2	V111 E112 T113 H120 N322	V111-G115 PolarHBondContact O-N 3.15Å; E112-G115 PolarHBondContact O-N 3.26Å; T113-G115 VanDerWaalsContact C-N 3.25Å; T113-G115 PolarHBondContact O-N 3.03Å; G115-H120 PolarHBondContact O-CE1 3.33Å; G115-H120 PolarHBondContact O-ND1 3.15Å; G115-H120 VanDerWaalsContact O-ND1 3.08Å; G115-N322 PolarHBondContact O-ND2 3.38Å
116	F	89.1	Confident	88.8	Confident	73 Å²	73	44.8 Å²	44.8	32%	0.32	23%	0.231	S	C	.	.	S	Bend	trans	-75.1	141.4	175.1	-170.6	-92.1	0	0	0	110.8	H120 V121 Y242 L246	F116-H120 HydrophobicContact CD2-CB 3.46Å; F116-H120 VanDerWaalsContact CD2-CB 3.46Å; F116-H120 HydrophobicContact CE2-CB 3.34Å; F116-H120 HydrophobicContact CG-CB 4.19Å; F116-H120 HydrophobicContact CZ-CB 3.98Å; F116-V121 HydrophobicContact CE1-CG2 3.64Å; F116-V121 HydrophobicContact CZ-CG2 3.74Å; F116-Y242 HydrophobicContact CB-CD1 4.37Å; F116-Y242 HydrophobicContact CB-CD2 3.82Å; F116-Y242 HydrophobicContact CB-CE1 4.23Å; F116-Y242 HydrophobicContact CB-CE2 3.66Å; F116-Y242 HydrophobicContact CB-CG 4.18Å; F116-Y242 HydrophobicContact CD2-CG 4.34Å; F116-Y242 HydrophobicContact CG-CD1 4.47Å; F116-Y242 HydrophobicContact CG-CG 4.43Å; F116-L246 HydrophobicContact CD2-CD1 4.12Å; F116-L246 HydrophobicContact CE2-CD1 3.61Å; F116-L246 HydrophobicContact CE2-CD2 4.34Å
117	G	91.5	Very high	88.9	Confident	17 Å²	17	43.2 Å²	43.2	18%	0.175	22%	0.222	C	C	.	.			trans	-173.7	-166.2	-173.2	0	0	0	0	0	113.5	F119 H120 V121 N322	G117-F119 VanDerWaalsContact C-N 3.3Å; G117-F119 PolarHBondContact O-N 3.47Å; G117-H120 PolarHBondContact N-ND1 3.01Å; G117-H120 WeakPolarHBondContact O-CA 3.01Å; G117-H120 WeakPolarHBondContact O-CB 3.08Å; G117-H120 PolarHBondContact O-N 3.35Å; G117-V121 PolarHBondContact O-N 2.8Å; G117-V121 VanDerWaalsContact O-N 3.07Å; G117-N322 VanDerWaalsContact C-OD1 3.24Å; G117-N322 WeakPolarHBondContact CA-OD1 3.18Å
118	R	91.9	Very high	89.2	Confident	159 Å²	159	43.3 Å²	43.3	60%	0.6	22%	0.222	S	C	*	.	H	α-helix	trans	-57.2	-37.4	-172.2	-64.9	-179.9	173.4	-163	-5.9	113.7	H120 V121 L122 N322	R118-H120 VanDerWaalsContact C-N 3.33Å; R118-V121 PolarHBondContact O-N 3.3Å; R118-L122 WeakPolarHBondContact O-CB 3.44Å; R118-L122 PolarHBondContact O-N 2.66Å; R118-N322 PolarHBondContact N-OD1 3.18Å; R118-N322 VanDerWaalsContact N-OD1 3.11Å
119	F	92.7	Very high	89.7	Confident	3 Å²	3	40.9 Å²	40.9	1%	0.013	21%	0.214	C	C	.	.	H	α-helix	trans	-62.5	-42	174.3	174.2	-97.3	0	0	0	111.7	G117 L122 L123 F237 P296 I318 M321 N322	G117-F119 VanDerWaalsContact C-N 3.3Å; G117-F119 PolarHBondContact O-N 3.47Å; F119-L122 PolarHBondContact O-N 3.07Å; F119-L123 HydrophobicContact CE1-CB 4.47Å; F119-L123 HydrophobicContact CE1-CD2 4.3Å; F119-L123 HydrophobicContact CZ-CD1 4.5Å; F119-L123 VanDerWaalsContact O-CB 3.29Å; F119-L123 WeakPolarHBondContact O-CB 3.37Å; F119-L123 PolarHBondContact O-N 3.1Å; F119-F237 HydrophobicContact CE1-CB 4.36Å; F119-F237 AromaticContact CE1-CD1 3.87Å; F119-F237 HydrophobicContact CE1-CD1 3.87Å; F119-F237 HydrophobicContact CE1-CE1 4.37Å; F119-F237 HydrophobicContact CE1-CG 4.14Å; F119-F237 HydrophobicContact CZ-CD1 4.16Å; F119-F237 HydrophobicContact CZ-CE1 4.22Å; F119-P296 HydrophobicContact CE2-CG 4.14Å; F119-P296 HydrophobicContact CZ-CG 4.02Å; F119-I318 HydrophobicContact CB-CG2 4.1Å; F119-I318 HydrophobicContact CD1-CB 4.27Å; F119-I318 HydrophobicContact CD1-CD1 4.18Å; F119-I318 HydrophobicContact CD1-CG1 3.8Å; F119-I318 HydrophobicContact CD1-CG2 3.59Å; F119-I318 HydrophobicContact CD2-CG1 4.22Å; F119-I318 HydrophobicContact CE1-CD1 3.74Å; F119-I318 HydrophobicContact CE1-CG1 3.74Å; F119-I318 HydrophobicContact CE1-CG2 4.25Å; F119-I318 HydrophobicContact CE2-CG1 4.17Å; F119-I318 HydrophobicContact CG-CB 4.39Å; F119-I318 HydrophobicContact CG-CG1 4.03Å; F119-I318 HydrophobicContact CG-CG2 3.94Å; F119-I318 HydrophobicContact CZ-CD1 4.08Å; F119-I318 HydrophobicContact CZ-CG1 3.94Å; F119-M321 HydrophobicContact CB-CB 4.03Å; F119-M321 HydrophobicContact CB-CE 4.2Å; F119-M321 HydrophobicContact CB-SD 4.4Å; F119-M321 HydrophobicContact CD2-CE 4.06Å; F119-M321 HydrophobicContact CD2-SD 3.87Å; F119-N322 WeakPolarHBondContact CB-OD1 3.4Å; F119-N322 PolarHBondContact N-OD1 3.32Å
120	H	91.5	Very high	90	Very high	4 Å²	4	36.5 Å²	36.5	2%	0.019	19%	0.194	C	C	.	.	H	α-helix	trans	-69.9	-34.5	-178.7	-61.9	111.5	0	0	0	112.4	G115 F116 G117 R118 F124 F237 N322	G115-H120 PolarHBondContact O-CE1 3.33Å; G115-H120 PolarHBondContact O-ND1 3.15Å; G115-H120 VanDerWaalsContact O-ND1 3.08Å; F116-H120 HydrophobicContact CD2-CB 3.46Å; F116-H120 VanDerWaalsContact CD2-CB 3.46Å; F116-H120 HydrophobicContact CE2-CB 3.34Å; F116-H120 HydrophobicContact CG-CB 4.19Å; F116-H120 HydrophobicContact CZ-CB 3.98Å; G117-H120 PolarHBondContact N-ND1 3.01Å; G117-H120 WeakPolarHBondContact O-CA 3.01Å; G117-H120 WeakPolarHBondContact O-CB 3.08Å; G117-H120 PolarHBondContact O-N 3.35Å; R118-H120 VanDerWaalsContact C-N 3.33Å; H120-F124 VanDerWaalsContact O-CB 3.26Å; H120-F124 WeakPolarHBondContact O-CB 3.42Å; H120-F124 PolarHBondContact O-N 3.27Å; H120-F237 PolarHBondContact NE2-O 3.45Å; H120-F237 VanDerWaalsContact NE2-O 3.15Å; H120-N322 PolarHBondContact CE1-ND2 3.25Å; H120-N322 VanDerWaalsContact CE1-ND2 3.31Å; H120-N322 PolarHBondContact ND1-ND2 3Å; H120-N322 VanDerWaalsContact ND1-ND2 3.18Å
121	V	91.4	Very high	90.2	Very high	73 Å²	73	37.8 Å²	37.8	44%	0.442	20%	0.201	S	C	.	.	H	α-helix	trans	-65	-47.6	170.4	179	0	0	0	0	110.9	F116 G117 R118 L123 F124 V125	F116-V121 HydrophobicContact CE1-CG2 3.64Å; F116-V121 HydrophobicContact CZ-CG2 3.74Å; G117-V121 PolarHBondContact O-N 2.8Å; G117-V121 VanDerWaalsContact O-N 3.07Å; R118-V121 PolarHBondContact O-N 3.3Å; V121-L123 PolarHBondContact O-N 3.12Å; V121-F124 PolarHBondContact O-N 3.07Å; V121-V125 WeakPolarHBondContact O-CG2 3.27Å; V121-V125 PolarHBondContact O-N 3.1Å
122	L	92.4	Very high	90.6	Very high	64 Å²	64	38.5 Å²	38.5	34%	0.335	20%	0.204	S	C	.	.	H	α-helix	trans	-60.3	-45	177.3	-177.9	66.7	0	0	0	111.8	R118 F119 V125 I126 F294 M321	R118-L122 WeakPolarHBondContact O-CB 3.44Å; R118-L122 PolarHBondContact O-N 2.66Å; F119-L122 PolarHBondContact O-N 3.07Å; L122-V125 PolarHBondContact O-N 3Å; L122-I126 HydrophobicContact CD1-CD1 3.78Å; L122-I126 HydrophobicContact CD1-CG1 4.22Å; L122-I126 HydrophobicContact CD2-CD1 4.48Å; L122-I126 HydrophobicContact CG-CD1 3.82Å; L122-I126 HydrophobicContact CG-CG1 4.5Å; L122-I126 WeakPolarHBondContact O-CG1 3.33Å; L122-I126 PolarHBondContact O-N 3.47Å; L122-F294 HydrophobicContact CD2-CB 4.32Å; L122-M321 HydrophobicContact CD2-CE 3.92Å
123	L	90.9	Very high	90.9	Very high	3 Å²	3	33.7 Å²	33.7	2%	0.016	18%	0.182	C	C	.	.	H	α-helix	trans	-59.5	-46	175	-177.3	76.1	0	0	0	110.9	F119 V121 V125 M127 F237 I295	F119-L123 HydrophobicContact CE1-CB 4.47Å; F119-L123 HydrophobicContact CE1-CD2 4.3Å; F119-L123 HydrophobicContact CZ-CD1 4.5Å; F119-L123 VanDerWaalsContact O-CB 3.29Å; F119-L123 WeakPolarHBondContact O-CB 3.37Å; F119-L123 PolarHBondContact O-N 3.1Å; V121-L123 PolarHBondContact O-N 3.12Å; L123-V125 VanDerWaalsContact C-N 3.33Å; L123-V125 PolarHBondContact O-N 3.42Å; L123-M127 HydrophobicContact CD1-CG 3.7Å; L123-M127 HydrophobicContact CG-CG 4.12Å; L123-M127 WeakPolarHBondContact O-CA 3.18Å; L123-M127 WeakPolarHBondContact O-CB 3.27Å; L123-M127 VanDerWaalsContact O-CG 3.32Å; L123-M127 WeakPolarHBondContact O-CG 3.43Å; L123-M127 PolarHBondContact O-N 2.89Å; L123-F237 HydrophobicContact CD1-CD2 4.09Å; L123-F237 HydrophobicContact CD1-CE2 4.44Å; L123-F237 HydrophobicContact CD2-CB 3.42Å; L123-F237 VanDerWaalsContact CD2-CB 3.42Å; L123-F237 HydrophobicContact CD2-CD2 3.78Å; L123-F237 HydrophobicContact CD2-CG 3.86Å; L123-I295 HydrophobicContact CD1-CD1 4.23Å; L123-I295 HydrophobicContact CD1-CG1 4.19Å; L123-I295 HydrophobicContact CD1-CG2 3.94Å
124	F	90.4	Very high	91.2	Very high	33 Å²	33	30.7 Å²	30.7	15%	0.145	16%	0.162	C	C	.	.	H	α-helix	trans	-63.4	-37.2	178.7	-176.5	-105.5	0	0	0	112.4	H120 V121 G128 L246 L249 F253	H120-F124 VanDerWaalsContact O-CB 3.26Å; H120-F124 WeakPolarHBondContact O-CB 3.42Å; H120-F124 PolarHBondContact O-N 3.27Å; V121-F124 PolarHBondContact O-N 3.07Å; F124-G128 WeakPolarHBondContact O-CA 3.23Å; F124-G128 PolarHBondContact O-N 2.86Å; F124-L246 HydrophobicContact CD1-CD2 4.32Å; F124-L246 HydrophobicContact CD2-CB 4.42Å; F124-L246 HydrophobicContact CD2-CD2 3.67Å; F124-L246 HydrophobicContact CE2-CB 4.32Å; F124-L246 HydrophobicContact CE2-CD2 3.9Å; F124-L246 WeakPolarHBondContact CE2-O 3.47Å; F124-L246 HydrophobicContact CG-CD2 3.9Å; F124-L246 HydrophobicContact CZ-CD2 4.31Å; F124-L249 HydrophobicContact CE1-CD2 3.68Å; F124-L249 HydrophobicContact CE1-CG 4.18Å; F124-L249 HydrophobicContact CE2-CB 4.49Å; F124-L249 HydrophobicContact CZ-CB 3.85Å; F124-L249 HydrophobicContact CZ-CD2 3.57Å; F124-L249 HydrophobicContact CZ-CG 3.71Å; F124-F253 HydrophobicContact CD1-CE2 4.2Å; F124-F253 HydrophobicContact CD1-CZ 4.39Å; F124-F253 AromaticContact CE1-CE2 3.58Å; F124-F253 HydrophobicContact CE1-CE2 3.58Å; F124-F253 AromaticContact CE1-CZ 3.99Å; F124-F253 HydrophobicContact CE1-CZ 3.99Å; F124-F253 HydrophobicContact CE2-CE2 4.17Å; F124-F253 HydrophobicContact CZ-CD2 4.4Å; F124-F253 AromaticContact CZ-CE2 3.56Å; F124-F253 HydrophobicContact CZ-CE2 3.56Å; F124-F253 HydrophobicContact CZ-CZ 4.42Å
125	V	91.4	Very high	91.3	Very high	76 Å²	76	30.3 Å²	30.3	46%	0.461	16%	0.16	S	C	.	.	H	α-helix	trans	-71.1	-50.5	176.3	172.5	0	0	0	0	111.9	V121 L122 L123 G128 S129	V121-V125 WeakPolarHBondContact O-CG2 3.27Å; V121-V125 PolarHBondContact O-N 3.1Å; L122-V125 PolarHBondContact O-N 3Å; L123-V125 VanDerWaalsContact C-N 3.33Å; L123-V125 PolarHBondContact O-N 3.42Å; V125-G128 PolarHBondContact O-N 3.04Å; V125-S129 PolarHBondContact O-N 3.28Å; V125-S129 PolarHBondContact O-OG 2.77Å
126	I	92	Very high	91.7	Very high	5 Å²	5	29.6 Å²	29.6	3%	0.026	15%	0.152	C	C	.	.	H	α-helix	trans	-68	-45.8	-178.2	-60	170.8	0	0	0	110.6	L122 G128 S129 A130 L288 L291 F294 I295	L122-I126 HydrophobicContact CD1-CD1 3.78Å; L122-I126 HydrophobicContact CD1-CG1 4.22Å; L122-I126 HydrophobicContact CD2-CD1 4.48Å; L122-I126 HydrophobicContact CG-CD1 3.82Å; L122-I126 HydrophobicContact CG-CG1 4.5Å; L122-I126 WeakPolarHBondContact O-CG1 3.33Å; L122-I126 PolarHBondContact O-N 3.47Å; I126-G128 VanDerWaalsContact C-N 3.26Å; I126-G128 PolarHBondContact O-N 3.39Å; I126-S129 PolarHBondContact O-OG 3.06Å; I126-S129 VanDerWaalsContact O-OG 3.07Å; I126-A130 PolarHBondContact O-N 3.34Å; I126-A130 VanDerWaalsContact O-N 3.11Å; I126-L288 HydrophobicContact CG2-CD2 4.1Å; I126-L288 WeakPolarHBondContact O-CD2 3.28Å; I126-L291 HydrophobicContact CD1-CB 4.28Å; I126-L291 HydrophobicContact CG1-CB 4.3Å; I126-L291 HydrophobicContact CG2-CB 3.95Å; I126-F294 HydrophobicContact CD1-CB 4.04Å; I126-I295 HydrophobicContact CB-CD1 4.1Å; I126-I295 HydrophobicContact CD1-CG1 4.47Å; I126-I295 HydrophobicContact CG2-CD1 3.63Å; I126-I295 HydrophobicContact CG2-CG1 4.35Å
127	M	89.1	Confident	91.9	Very high	1 Å²	1	26.2 Å²	26.2	1%	0.005	14%	0.137	C	C	.	.	H	α-helix	trans	-77.4	-15.1	177.2	-59.3	-97.4	60.7	0	0	112.6	L123 A130 V190 L233 K234 F292 I295	L123-M127 HydrophobicContact CD1-CG 3.7Å; L123-M127 HydrophobicContact CG-CG 4.12Å; L123-M127 WeakPolarHBondContact O-CA 3.18Å; L123-M127 WeakPolarHBondContact O-CB 3.27Å; L123-M127 VanDerWaalsContact O-CG 3.32Å; L123-M127 WeakPolarHBondContact O-CG 3.43Å; L123-M127 PolarHBondContact O-N 2.89Å; M127-A130 HydrophobicContact CE-CB 3.96Å; M127-A130 WeakPolarHBondContact O-CB 3.44Å; M127-V190 HydrophobicContact CE-CG1 4.24Å; M127-L233 HydrophobicContact SD-CD2 4.14Å; M127-K234 HydrophobicContact CB-CD 3.41Å; M127-K234 VanDerWaalsContact CB-CD 3.41Å; M127-K234 HydrophobicContact CB-CG 3.38Å; M127-K234 HydrophobicContact CG-CD 4.37Å; M127-K234 HydrophobicContact CG-CG 3.81Å; M127-K234 WeakPolarHBondContact O-CE 3.48Å; M127-K234 PolarHBondContact O-NZ 3.48Å; M127-K234 HydrophobicContact SD-CG 4.15Å; M127-F292 HydrophobicContact CE-CE1 3.45Å; M127-F292 VanDerWaalsContact CE-CE1 3.45Å; M127-F292 HydrophobicContact CE-CZ 3.37Å; M127-F292 HydrophobicContact SD-CE1 4.48Å; M127-I295 HydrophobicContact CE-CD1 4.14Å; M127-I295 HydrophobicContact CG-CD1 3.64Å; M127-I295 HydrophobicContact SD-CD1 3.83Å
128	G	90.2	Very high	91.9	Very high	2 Å²	2	25.7 Å²	25.7	2%	0.021	13%	0.13	C	C	.	.	H	α-helix	trans	-75	-51	170	0	0	0	0	0	111.2	F124 V125 I126 A130 N131 I132 F253	F124-G128 WeakPolarHBondContact O-CA 3.23Å; F124-G128 PolarHBondContact O-N 2.86Å; V125-G128 PolarHBondContact O-N 3.04Å; I126-G128 VanDerWaalsContact C-N 3.26Å; I126-G128 PolarHBondContact O-N 3.39Å; G128-A130 PolarHBondContact O-N 3.14Å; G128-N131 WeakPolarHBondContact O-CA 3.39Å; G128-N131 VanDerWaalsContact O-CB 3.31Å; G128-N131 WeakPolarHBondContact O-CB 3.47Å; G128-N131 PolarHBondContact O-N 3.31Å; G128-I132 PolarHBondContact O-N 3.02Å; G128-F253 VanDerWaalsContact C-CD1 3.46Å; G128-F253 VanDerWaalsContact C-CG 3.41Å; G128-F253 WeakPolarHBondContact O-CB 3.41Å; G128-F253 VanDerWaalsContact O-CG 3.24Å; G128-F253 WeakPolarHBondContact O-CG 3.42Å
129	S	91.6	Very high	92	Very high	27 Å²	27	18.5 Å²	18.5	19%	0.189	10%	0.104	C	C	.	.	H	α-helix	trans	-60.2	-26.8	173.7	42.5	0	0	0	0	113.1	V125 I126 N131 I132 V133 L288	V125-S129 PolarHBondContact O-N 3.28Å; V125-S129 PolarHBondContact O-OG 2.77Å; I126-S129 PolarHBondContact O-OG 3.06Å; I126-S129 VanDerWaalsContact O-OG 3.07Å; S129-N131 VanDerWaalsContact C-N 3.33Å; S129-N131 PolarHBondContact O-N 3.01Å; S129-I132 VanDerWaalsContact O-CB 3.25Å; S129-I132 WeakPolarHBondContact O-CB 3.46Å; S129-I132 PolarHBondContact O-N 2.9Å; S129-V133 PolarHBondContact O-N 3.01Å; S129-L288 WeakPolarHBondContact OG-CD2 3.3Å
130	A	90.7	Very high	92.1	Very high	3 Å²	3	18.4 Å²	18.4	3%	0.025	10%	0.103	C	C	.	.	H	α-helix	trans	-54.3	-42.6	164	0	0	0	0	0	113.8	I126 M127 G128 I132 V133 E134 Y194 L288	I126-A130 PolarHBondContact O-N 3.34Å; I126-A130 VanDerWaalsContact O-N 3.11Å; M127-A130 HydrophobicContact CE-CB 3.96Å; M127-A130 WeakPolarHBondContact O-CB 3.44Å; G128-A130 PolarHBondContact O-N 3.14Å; A130-I132 VanDerWaalsContact C-N 3.27Å; A130-I132 PolarHBondContact O-N 3.48Å; A130-V133 PolarHBondContact O-N 3.47Å; A130-E134 PolarHBondContact O-N 2.9Å; A130-E134 VanDerWaalsContact O-N 3.08Å; A130-Y194 WeakPolarHBondContact CA-OH 3.5Å; A130-Y194 HydrophobicContact CB-CE2 4.09Å; A130-Y194 WeakPolarHBondContact CB-OH 3.38Å; A130-Y194 PolarHBondContact O-OH 3.07Å; A130-L288 HydrophobicContact CB-CD1 4.43Å
131	N	90.8	Very high	92.1	Very high	27 Å²	27	18.6 Å²	18.6	14%	0.144	11%	0.105	C	C	.	.	H	α-helix	trans	-66.8	-26.6	174.2	-71.6	12.2	0	0	0	112.8	G128 S129 A135 K234 F253	G128-N131 WeakPolarHBondContact O-CA 3.39Å; G128-N131 VanDerWaalsContact O-CB 3.31Å; G128-N131 WeakPolarHBondContact O-CB 3.47Å; G128-N131 PolarHBondContact O-N 3.31Å; S129-N131 VanDerWaalsContact C-N 3.33Å; S129-N131 PolarHBondContact O-N 3.01Å; N131-A135 VanDerWaalsContact O-CB 3.28Å; N131-A135 WeakPolarHBondContact O-CB 3.43Å; N131-A135 PolarHBondContact O-N 3.33Å; N131-K234 PolarHBondContact OD1-NZ 3.22Å; N131-F253 HydrophobicContact CB-CB 3.92Å
132	I	94	Very high	92	Very high	25 Å²	25	15.5 Å²	15.5	13%	0.128	9%	0.087	C	C	.	.	H	α-helix	trans	-61.1	-49.4	173.1	-57.8	174.6	0	0	0	108.8	G128 S129 A130 A135 M136 F253 T256 G257 L260	G128-I132 PolarHBondContact O-N 3.02Å; S129-I132 VanDerWaalsContact O-CB 3.25Å; S129-I132 WeakPolarHBondContact O-CB 3.46Å; S129-I132 PolarHBondContact O-N 2.9Å; A130-I132 VanDerWaalsContact C-N 3.27Å; A130-I132 PolarHBondContact O-N 3.48Å; I132-A135 PolarHBondContact O-N 3.15Å; I132-M136 HydrophobicContact CG2-CG 4.39Å; I132-M136 HydrophobicContact CG2-SD 3.95Å; I132-M136 VanDerWaalsContact O-CG 3.26Å; I132-M136 WeakPolarHBondContact O-CG 3.42Å; I132-M136 PolarHBondContact O-N 3.28Å; I132-F253 WeakPolarHBondContact CA-O 3.48Å; I132-F253 HydrophobicContact CD1-CD1 4.02Å; I132-F253 HydrophobicContact CG1-CB 3.99Å; I132-F253 HydrophobicContact CG1-CD1 4Å; I132-F253 HydrophobicContact CG1-CG 4.49Å; I132-F253 WeakPolarHBondContact CG1-O 3.41Å; I132-T256 HydrophobicContact CD1-CG2 4.02Å; I132-T256 HydrophobicContact CG1-CG2 4.36Å; I132-G257 WeakPolarHBondContact O-CA 3.19Å; I132-L260 HydrophobicContact CG2-CD2 4.39Å
133	V	93.3	Very high	92.1	Very high	4 Å²	4	12.5 Å²	12.5	2%	0.024	7%	0.071	C	C	.	.	H	α-helix	trans	-65.7	-42.5	-179.5	167.7	0	0	0	0	112.4	S129 A130 A135 M136 E137 Y194 P284 S285 L288	S129-V133 PolarHBondContact O-N 3.01Å; A130-V133 PolarHBondContact O-N 3.47Å; V133-A135 VanDerWaalsContact C-N 3.34Å; V133-A135 PolarHBondContact O-N 3.35Å; V133-M136 PolarHBondContact O-N 3.03Å; V133-E137 PolarHBondContact O-N 3.02Å; V133-Y194 HydrophobicContact CB-CE1 4.04Å; V133-Y194 HydrophobicContact CG1-CD1 4.47Å; V133-Y194 HydrophobicContact CG1-CE1 3.81Å; V133-P284 HydrophobicContact CG2-CB 3.86Å; V133-S285 WeakPolarHBondContact CG1-OG 3.47Å; V133-L288 HydrophobicContact CB-CD1 4.24Å; V133-L288 HydrophobicContact CG2-CD1 3.67Å
134	E	92.5	Very high	92.2	Very high	18 Å²	18	12.4 Å²	12.4	8%	0.084	7%	0.07	C	C	.	.	H	α-helix	trans	-58.4	-45.9	174.3	178.6	169.1	-167.9	0	0	111.5	A130 I138 V224 V227 W254	A130-E134 PolarHBondContact O-N 2.9Å; A130-E134 VanDerWaalsContact O-N 3.08Å; E134-I138 HydrophobicContact CG-CD1 3.86Å; E134-I138 WeakPolarHBondContact O-CD1 3.5Å; E134-I138 WeakPolarHBondContact O-CG1 3.46Å; E134-I138 PolarHBondContact O-N 2.85Å; E134-V224 HydrophobicContact CG-CG1 3.94Å; E134-V227 HydrophobicContact CB-CG1 4.11Å; E134-W254 HydrophobicContact CG-CH2 4.44Å; E134-W254 HydrophobicContact CG-CZ3 3.84Å
135	A	93.6	Very high	92.1	Very high	0 Å²	0	11 Å²	11	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-64.6	-42.7	176.8	0	0	0	0	0	112.1	N131 I132 V133 M139 W254	N131-A135 VanDerWaalsContact O-CB 3.28Å; N131-A135 WeakPolarHBondContact O-CB 3.43Å; N131-A135 PolarHBondContact O-N 3.33Å; I132-A135 PolarHBondContact O-N 3.15Å; V133-A135 VanDerWaalsContact C-N 3.34Å; V133-A135 PolarHBondContact O-N 3.35Å; A135-M139 WeakPolarHBondContact O-CB 3.43Å; A135-M139 WeakPolarHBondContact O-CG 3.33Å; A135-M139 PolarHBondContact O-N 3.25Å; A135-W254 HydrophobicContact CB-CB 4.4Å; A135-W254 HydrophobicContact CB-CD2 3.61Å; A135-W254 HydrophobicContact CB-CE3 3.88Å; A135-W254 HydrophobicContact CB-CG 3.86Å; A135-W254 HydrophobicContact CB-CZ2 4.46Å; A135-W254 HydrophobicContact CB-CZ3 4.42Å; A135-W254 VanDerWaalsContact CB-O 3.28Å; A135-W254 WeakPolarHBondContact CB-O 3.43Å
136	M	94.9	Very high	91.9	Very high	4 Å²	4	7.3 Å²	7.3	2%	0.02	4%	0.042	C	C	.	.	H	α-helix	trans	-56.7	-53.1	176	-73.7	173.6	77.4	0	0	111.2	I132 V133 I138 M139 L140 G257 L260 I261 L264 P284	I132-M136 HydrophobicContact CG2-CG 4.39Å; I132-M136 HydrophobicContact CG2-SD 3.95Å; I132-M136 VanDerWaalsContact O-CG 3.26Å; I132-M136 WeakPolarHBondContact O-CG 3.42Å; I132-M136 PolarHBondContact O-N 3.28Å; V133-M136 PolarHBondContact O-N 3.03Å; M136-I138 VanDerWaalsContact C-N 3.34Å; M136-I138 PolarHBondContact O-N 3.42Å; M136-M139 PolarHBondContact O-N 3.25Å; M136-L140 VanDerWaalsContact O-CB 3.23Å; M136-L140 WeakPolarHBondContact O-CB 3.11Å; M136-L140 PolarHBondContact O-N 2.82Å; M136-G257 VanDerWaalsContact CG-O 3.25Å; M136-G257 WeakPolarHBondContact CG-O 3.5Å; M136-L260 HydrophobicContact CE-CB 4.49Å; M136-L260 HydrophobicContact CE-CD2 3.92Å; M136-L260 HydrophobicContact CE-CG 3.92Å; M136-L260 HydrophobicContact SD-CB 4.35Å; M136-L260 HydrophobicContact SD-CD2 3.7Å; M136-L260 HydrophobicContact SD-CG 4.13Å; M136-I261 HydrophobicContact CB-CB 4.44Å; M136-I261 HydrophobicContact CG-CB 4.3Å; M136-L264 HydrophobicContact CE-CD1 3.87Å; M136-P284 HydrophobicContact CE-CG 4.39Å; M136-P284 HydrophobicContact SD-CG 4.22Å
137	E	93.8	Very high	91.9	Very high	3 Å²	3	8.5 Å²	8.5	1%	0.014	5%	0.048	C	C	.	.	H	α-helix	trans	-61.2	-38.6	-175.7	-76.7	-65	167.9	0	0	113.8	V133 S201 R217 V220 V224	V133-E137 PolarHBondContact O-N 3.02Å; E137-S201 WeakPolarHBondContact OE1-CB 3.49Å; E137-S201 PolarHBondContact OE1-OG 3.28Å; E137-S201 PolarHBondContact OE2-OG 3.16Å; E137-R217 PolarHBondContact O-NH1 2.95Å; E137-R217 VanDerWaalsContact O-NH1 3.13Å; E137-R217 IonicContact OE2-NH1 3.14Å; E137-R217 PolarHBondContact OE2-NH1 2.98Å; E137-V220 HydrophobicContact CB-CG1 4.32Å; E137-V220 HydrophobicContact CG-CG1 4.36Å; E137-V220 WeakPolarHBondContact OE2-CG1 3.48Å; E137-V224 HydrophobicContact CB-CG2 4.1Å
138	I	91.9	Very high	92	Very high	5 Å²	5	8.5 Å²	8.5	3%	0.026	5%	0.048	C	C	.	.	H	α-helix	trans	-76.8	-43.3	179.5	-59.8	166.4	0	0	0	110.8	E134 M136 L140 F167 F170 V224 W254 Y369	E134-I138 HydrophobicContact CG-CD1 3.86Å; E134-I138 WeakPolarHBondContact O-CD1 3.5Å; E134-I138 WeakPolarHBondContact O-CG1 3.46Å; E134-I138 PolarHBondContact O-N 2.85Å; M136-I138 VanDerWaalsContact C-N 3.34Å; M136-I138 PolarHBondContact O-N 3.42Å; I138-L140 VanDerWaalsContact C-N 3.31Å; I138-L140 PolarHBondContact O-N 3.44Å; I138-F167 HydrophobicContact CG2-CE1 4.21Å; I138-F167 HydrophobicContact CG2-CZ 3.95Å; I138-F170 HydrophobicContact CD1-CE1 4.25Å; I138-V224 HydrophobicContact CD1-CG1 4Å; I138-V224 HydrophobicContact CG1-CG1 4.25Å; I138-W254 HydrophobicContact CD1-CH2 3.72Å; I138-W254 HydrophobicContact CD1-CZ3 4.43Å; I138-Y369 HydrophobicContact CG2-CD1 4.38Å; I138-Y369 HydrophobicContact CG2-CE1 3.55Å
139	M	93.5	Very high	91.9	Very high	9 Å²	9	8.5 Å²	8.5	4%	0.044	5%	0.047	C	C	.	.	H	α-helix	trans	-74.4	-19.8	179.9	-62.6	-68.4	96.7	0	0	113.2	A135 M136 L141 A142 I261 Y368 Y369 V372	A135-M139 WeakPolarHBondContact O-CB 3.43Å; A135-M139 WeakPolarHBondContact O-CG 3.33Å; A135-M139 PolarHBondContact O-N 3.25Å; M136-M139 PolarHBondContact O-N 3.25Å; M139-L141 PolarHBondContact O-N 3.45Å; M139-L141 VanDerWaalsContact O-N 3.09Å; M139-A142 PolarHBondContact O-N 2.95Å; M139-I261 HydrophobicContact CB-CG2 3.85Å; M139-Y368 HydrophobicContact CE-CE1 3.96Å; M139-Y369 HydrophobicContact CE-CD1 3.92Å; M139-Y369 HydrophobicContact CE-CE1 3.74Å; M139-V372 HydrophobicContact CE-CG1 4.37Å; M139-V372 HydrophobicContact CE-CG2 4.23Å; M139-V372 HydrophobicContact SD-CB 4.5Å; M139-V372 HydrophobicContact SD-CG1 3.81Å; M139-V372 HydrophobicContact SD-CG2 3.97Å
140	L	94.4	Very high	91.7	Very high	1 Å²	1	8.7 Å²	8.7	1%	0.005	5%	0.048	C	C	.	.	H	α-helix	trans	-54.7	-29.3	178.1	-167	147.4	0	0	0	113.1	M136 I138 A142 V143 V144 I261 M277 I278	M136-L140 VanDerWaalsContact O-CB 3.23Å; M136-L140 WeakPolarHBondContact O-CB 3.11Å; M136-L140 PolarHBondContact O-N 2.82Å; I138-L140 VanDerWaalsContact C-N 3.31Å; I138-L140 PolarHBondContact O-N 3.44Å; L140-A142 PolarHBondContact O-N 3.22Å; L140-V143 PolarHBondContact O-N 3.44Å; L140-V144 HydrophobicContact CD2-CB 4.18Å; L140-V144 HydrophobicContact CD2-CG2 3.46Å; L140-V144 VanDerWaalsContact CD2-CG2 3.46Å; L140-V144 HydrophobicContact CG-CG2 4.12Å; L140-V144 WeakPolarHBondContact O-CB 3.4Å; L140-V144 WeakPolarHBondContact O-CG2 3.46Å; L140-V144 PolarHBondContact O-N 2.76Å; L140-I261 HydrophobicContact CB-CD1 4.34Å; L140-I261 HydrophobicContact CB-CG1 3.99Å; L140-I261 HydrophobicContact CD1-CD1 3.72Å; L140-I261 HydrophobicContact CD1-CG1 4.3Å; L140-I261 HydrophobicContact CG-CD1 3.97Å; L140-I261 HydrophobicContact CG-CG1 4.12Å; L140-M277 HydrophobicContact CG-CE 4.11Å; L140-I278 HydrophobicContact CD1-CG1 4.16Å; L140-I278 HydrophobicContact CD2-CD1 4.12Å; L140-I278 HydrophobicContact CD2-CG1 3.97Å
141	L	90.4	Very high	91.6	Very high	8 Å²	8	13 Å²	13	4%	0.042	7%	0.068	C	C	.	.	H	α-helix	trans	-58.5	-45.3	175	-69.5	164.3	0	0	0	112.4	M139 V143 V144 S145 V162 V166 R217	M139-L141 PolarHBondContact O-N 3.45Å; M139-L141 VanDerWaalsContact O-N 3.09Å; L141-V143 PolarHBondContact O-N 3.27Å; L141-V144 PolarHBondContact O-N 3.14Å; L141-S145 WeakPolarHBondContact O-CB 3.42Å; L141-S145 PolarHBondContact O-N 3.44Å; L141-S145 PolarHBondContact O-OG 3.47Å; L141-S145 VanDerWaalsContact O-OG 3.05Å; L141-V162 HydrophobicContact CD2-CG1 3.69Å; L141-V166 HydrophobicContact CD1-CB 4.34Å; L141-V166 HydrophobicContact CD1-CG2 4.1Å; L141-V166 HydrophobicContact CD2-CG2 4.35Å; L141-R217 VanDerWaalsContact CD2-NH2 3.33Å; L141-R217 VanDerWaalsContact CG-NH2 3.33Å
142	A	91.1	Very high	91.6	Very high	8 Å²	8	14.3 Å²	14.3	7%	0.066	7%	0.071	C	C	.	.	H	α-helix	trans	-65.5	-24.3	-177.2	0	0	0	0	0	113.2	M139 L140 V372 L373 S376	M139-A142 PolarHBondContact O-N 2.95Å; L140-A142 PolarHBondContact O-N 3.22Å; A142-V372 HydrophobicContact CB-CG1 3.78Å; A142-L373 HydrophobicContact CB-CD2 4.1Å; A142-S376 WeakPolarHBondContact O-CB 3.44Å
143	V	93.1	Very high	91.4	Very high	1 Å²	1	22.8 Å²	22.8	1%	0.006	10%	0.101	C	C	.	.	H	α-helix	trans	-89.2	-36.4	176.1	178.6	0	0	0	0	111.8	L140 L141 I262 M277 Y414	L140-V143 PolarHBondContact O-N 3.44Å; L141-V143 PolarHBondContact O-N 3.27Å; V143-I262 HydrophobicContact CG2-CG1 4.03Å; V143-M277 HydrophobicContact CB-CE 4.41Å; V143-M277 HydrophobicContact CG1-CE 3.92Å; V143-M277 HydrophobicContact CG1-SD 3.66Å; V143-Y414 HydrophobicContact CG1-CE1 4.06Å
144	V	92.9	Very high	91.2	Very high	1 Å²	1	23 Å²	23	1%	0.006	10%	0.102	C	C	.	.	H	α-helix	trans	-85.5	-22.8	-175.6	173	0	0	0	0	113.7	L140 L141 E147 I148 F213 W274 M277	L140-V144 HydrophobicContact CD2-CB 4.18Å; L140-V144 HydrophobicContact CD2-CG2 3.46Å; L140-V144 VanDerWaalsContact CD2-CG2 3.46Å; L140-V144 HydrophobicContact CG-CG2 4.12Å; L140-V144 WeakPolarHBondContact O-CB 3.4Å; L140-V144 WeakPolarHBondContact O-CG2 3.46Å; L140-V144 PolarHBondContact O-N 2.76Å; L141-V144 PolarHBondContact O-N 3.14Å; V144-E147 WeakPolarHBondContact O-CB 3.49Å; V144-E147 PolarHBondContact O-N 3.04Å; V144-I148 HydrophobicContact CG1-CD1 4.49Å; V144-I148 HydrophobicContact CG1-CG1 4.5Å; V144-I148 HydrophobicContact CG1-CG2 3.53Å; V144-I148 WeakPolarHBondContact O-CG1 3.14Å; V144-I148 PolarHBondContact O-N 3.18Å; V144-F213 HydrophobicContact CG1-CZ 3.97Å; V144-W274 HydrophobicContact CG1-CE3 4.34Å; V144-W274 HydrophobicContact CG2-CB 4.47Å; V144-M277 HydrophobicContact CG2-CE 3.29Å
145	S	89.9	Confident	91.1	Very high	2 Å²	2	27 Å²	27	1%	0.014	12%	0.12	C	C	.	.	H	α-helix	trans	-46.2	-52	179.8	-82.1	0	0	0	0	115.6	L141 E147 I148 R149 V159 Q521	L141-S145 WeakPolarHBondContact O-CB 3.42Å; L141-S145 PolarHBondContact O-N 3.44Å; L141-S145 PolarHBondContact O-OG 3.47Å; L141-S145 VanDerWaalsContact O-OG 3.05Å; S145-E147 VanDerWaalsContact C-N 3.35Å; S145-E147 PolarHBondContact O-N 3.3Å; S145-I148 WeakPolarHBondContact O-CG1 3.41Å; S145-R149 WeakPolarHBondContact O-CB 3.38Å; S145-R149 PolarHBondContact O-N 3Å; S145-R149 VanDerWaalsContact O-N 3.09Å; S145-V159 VanDerWaalsContact OG-CG1 3.31Å; S145-V159 WeakPolarHBondContact OG-CG1 3.21Å; S145-Q521 PolarHBondContact OG-NE2 3.05Å
146	P	87.4	Confident	90.8	Very high	0 Å²	0	28 Å²	28	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-58.8	-44.5	175.8	17.7	-31.2	0	0	0	113	I148 R149 C150 E380 F409	P146-I148 PolarHBondContact O-N 3.46Å; P146-R149 WeakPolarHBondContact O-CB 3.47Å; P146-R149 PolarHBondContact O-N 3.35Å; P146-C150 PolarHBondContact O-N 3.04Å; P146-C150 PolarHBondContact O-SG 2.73Å; P146-E380 WeakPolarHBondContact CA-OE1 3.14Å; P146-E380 VanDerWaalsContact CB-CD 3.49Å; P146-E380 HydrophobicContact CB-CG 3.94Å; P146-F409 HydrophobicContact CG-CD2 3.76Å; P146-F409 HydrophobicContact CG-CE2 3.58Å; P146-F409 HydrophobicContact CG-CG 4.47Å; P146-F409 HydrophobicContact CG-CZ 4.14Å
147	E	90.2	Very high	90.6	Very high	29 Å²	29	33.1 Å²	33.1	14%	0.136	15%	0.145	C	C	.	.	H	α-helix	trans	-66.1	-40.3	-173.2	-60.2	-63.6	132.1	0	0	112.2	V144 S145 E151 V269 W274	V144-E147 WeakPolarHBondContact O-CB 3.49Å; V144-E147 PolarHBondContact O-N 3.04Å; S145-E147 VanDerWaalsContact C-N 3.35Å; S145-E147 PolarHBondContact O-N 3.3Å; E147-E151 WeakPolarHBondContact O-CB 3.27Å; E147-E151 PolarHBondContact O-N 2.92Å; E147-V269 HydrophobicContact CG-CG1 3.78Å; E147-V269 WeakPolarHBondContact OE1-CG1 3.44Å; E147-V269 WeakPolarHBondContact OE2-CG1 3.41Å; E147-W274 HydrophobicContact CB-CB 3.85Å; E147-W274 HydrophobicContact CB-CG 3.89Å; E147-W274 HydrophobicContact CG-CB 4.1Å
148	I	91.3	Very high	90.6	Very high	2 Å²	2	34.8 Å²	34.8	1%	0.01	15%	0.153	C	C	.	.	H	α-helix	trans	-76.3	-28.8	175.1	62.9	177.6	0	0	0	112.8	V144 S145 P146 C150 W152 L154 V162 F213 W274	V144-I148 HydrophobicContact CG1-CD1 4.49Å; V144-I148 HydrophobicContact CG1-CG1 4.5Å; V144-I148 HydrophobicContact CG1-CG2 3.53Å; V144-I148 WeakPolarHBondContact O-CG1 3.14Å; V144-I148 PolarHBondContact O-N 3.18Å; S145-I148 WeakPolarHBondContact O-CG1 3.41Å; P146-I148 PolarHBondContact O-N 3.46Å; I148-C150 VanDerWaalsContact C-N 3.34Å; I148-W152 HydrophobicContact CB-CE3 3.99Å; I148-W152 HydrophobicContact CB-CZ3 3.99Å; I148-W152 HydrophobicContact CG2-CE3 4.27Å; I148-W152 HydrophobicContact CG2-CZ3 3.8Å; I148-W152 PolarHBondContact O-N 3.09Å; I148-L154 HydrophobicContact CB-CD1 4.43Å; I148-L154 HydrophobicContact CG1-CD1 4.31Å; I148-V162 HydrophobicContact CD1-CG2 4.2Å; I148-F213 HydrophobicContact CD1-CD1 4.36Å; I148-F213 HydrophobicContact CD1-CE1 3.57Å; I148-F213 HydrophobicContact CD1-CZ 4.16Å; I148-F213 HydrophobicContact CG2-CE1 4.12Å; I148-F213 HydrophobicContact CG2-CE2 4.28Å; I148-F213 HydrophobicContact CG2-CZ 3.86Å; I148-W274 HydrophobicContact CG2-CD2 4.45Å; I148-W274 HydrophobicContact CG2-CZ2 4.23Å
149	R	89.1	Confident	90.6	Very high	2 Å²	2	34.6 Å²	34.6	1%	0.008	15%	0.152	C	C	.	.	H	α-helix	trans	-61.9	-45.2	171.6	-178.1	-177.8	-82.7	141.7	-2.7	109.8	S145 P146 R153 L154 D156 V159 E377 E380	S145-R149 WeakPolarHBondContact O-CB 3.38Å; S145-R149 PolarHBondContact O-N 3Å; S145-R149 VanDerWaalsContact O-N 3.09Å; P146-R149 WeakPolarHBondContact O-CB 3.47Å; P146-R149 PolarHBondContact O-N 3.35Å; R149-R153 WeakPolarHBondContact O-CA 3.46Å; R149-R153 PolarHBondContact O-N 3.15Å; R149-L154 PolarHBondContact O-N 3.33Å; R149-L154 VanDerWaalsContact O-N 3.17Å; R149-D156 IonicContact CZ-OD1 2.78Å; R149-D156 IonicContact NE-OD1 3.97Å; R149-D156 IonicContact NH2-OD1 3.68Å; R149-D156 PolarHBondContact NH2-OD1 3.08Å; R149-V159 HydrophobicContact CB-CG2 4.05Å; R149-V159 HydrophobicContact CG-CG2 4.34Å; R149-E377 IonicContact CZ-OE2 3.16Å; R149-E377 IonicContact NH1-OE1 3.45Å; R149-E377 IonicContact NH1-OE2 3.72Å; R149-E377 PolarHBondContact NH1-OE2 3.07Å; R149-E377 VanDerWaalsContact NH1-OE2 3.15Å; R149-E377 IonicContact NH2-OE1 2.71Å; R149-E377 PolarHBondContact NH2-OE1 3.05Å; R149-E377 IonicContact NH2-OE2 3.41Å; R149-E377 PolarHBondContact NH2-OE2 2.91Å; R149-E380 WeakPolarHBondContact CD-OE1 3.46Å; R149-E380 IonicContact CZ-OE1 2.81Å; R149-E380 IonicContact CZ-OE2 2.69Å; R149-E380 IonicContact NE-OE1 2.73Å; R149-E380 IonicContact NH1-OE1 3.15Å; R149-E380 PolarHBondContact NH1-OE1 3.08Å; R149-E380 IonicContact NH1-OE2 3.47Å; R149-E380 PolarHBondContact NH1-OE2 3.12Å
150	C	86.6	Confident	90.6	Very high	31 Å²	31	34.1 Å²	34.1	21%	0.209	15%	0.15	C	C	.	.	H	α-helix	trans	-63.4	-54.1	173.9	-74.8	0	0	0	0	113.6	P146 I148 W152 C406	P146-C150 PolarHBondContact O-N 3.04Å; P146-C150 PolarHBondContact O-SG 2.73Å; I148-C150 VanDerWaalsContact C-N 3.34Å; C150-W152 PolarHBondContact O-N 3.41Å; C150-C406 HydrophobicContact CB-CB 4Å; C150-C406 WeakPolarHBondContact CB-SG 3.5Å; C150-C406 WeakPolarHBondContact SG-CA 3.4Å; C150-C406 WeakPolarHBondContact SG-CB 3.14Å; C150-C406 CovalentContact SG-SG 2.03Å; C150-C406 PolarHBondContact SG-SG 3.31Å
151	E	89.6	Confident	90.6	Very high	94 Å²	94	36 Å²	36	44%	0.439	16%	0.16	S	C	.	.	H	α-helix	trans	-57.8	-47	-175.3	177.4	86.4	179.9	0	0	112.7	E147 R275	E147-E151 WeakPolarHBondContact O-CB 3.27Å; E147-E151 PolarHBondContact O-N 2.92Å; E151-R275 VanDerWaalsContact CD-NH1 3.26Å; E151-R275 IonicContact OE1-CZ 2.77Å; E151-R275 IonicContact OE1-NH1 3.43Å; E151-R275 PolarHBondContact OE1-NH1 2.83Å; E151-R275 IonicContact OE1-NH2 3.05Å; E151-R275 PolarHBondContact OE1-NH2 3.46Å; E151-R275 IonicContact OE2-NH1 3.25Å; E151-R275 PolarHBondContact OE2-NH1 3.44Å
152	W	91.1	Very high	90.8	Very high	53 Å²	53	35.7 Å²	35.7	20%	0.201	16%	0.158	C	C	.	.	H	α-helix	trans	-107.8	5.7	-173.1	-66.1	-46.5	0	0	0	114.3	I148 C150 L154 A207 Y210 F213 W274	I148-W152 HydrophobicContact CB-CE3 3.99Å; I148-W152 HydrophobicContact CB-CZ3 3.99Å; I148-W152 HydrophobicContact CG2-CE3 4.27Å; I148-W152 HydrophobicContact CG2-CZ3 3.8Å; I148-W152 PolarHBondContact O-N 3.09Å; C150-W152 PolarHBondContact O-N 3.41Å; W152-L154 HydrophobicContact CB-CD1 4.46Å; W152-L154 HydrophobicContact CB-CD2 3.69Å; W152-L154 HydrophobicContact CB-CG 3.87Å; W152-L154 HydrophobicContact CE3-CD1 4.37Å; W152-L154 PolarHBondContact O-N 2.91Å; W152-A207 HydrophobicContact CH2-CB 4.46Å; W152-Y210 HydrophobicContact CE3-CD2 4.27Å; W152-F213 HydrophobicContact CH2-CB 3.57Å; W152-F213 HydrophobicContact CH2-CD1 4.45Å; W152-F213 AromaticContact CH2-CD2 3.77Å; W152-F213 HydrophobicContact CH2-CD2 3.77Å; W152-F213 AromaticContact CH2-CG 3.7Å; W152-F213 HydrophobicContact CH2-CG 3.7Å; W152-F213 HydrophobicContact CZ3-CB 3.75Å; W152-F213 AromaticContact CZ3-CD1 3.94Å; W152-F213 HydrophobicContact CZ3-CD1 3.94Å; W152-F213 HydrophobicContact CZ3-CD2 4.02Å; W152-F213 AromaticContact CZ3-CG 3.65Å; W152-F213 HydrophobicContact CZ3-CG 3.65Å; W152-W274 AromaticContact CH2-CH2 3.96Å; W152-W274 HydrophobicContact CH2-CH2 3.96Å; W152-W274 HydrophobicContact CH2-CZ2 4.07Å; W152-W274 HydrophobicContact CZ2-CZ2 4.43Å
153	R	88.9	Confident	90.9	Very high	204 Å²	204	35.3 Å²	35.3	77%	0.77	16%	0.155	S	C	*	.	T	Hydrogen-bonded Turn	trans	50.9	54.6	-178.6	-60.8	-178.4	-179.3	-176.2	-1.3	112.1	R149 C404	R149-R153 WeakPolarHBondContact O-CA 3.46Å; R149-R153 PolarHBondContact O-N 3.15Å; R153-C404 VanDerWaalsContact CA-SG 3.52Å; R153-C404 HydrophobicContact CB-CB 4.31Å; R153-C404 PolarHBondContact O-SG 2.97Å
154	L	89.4	Confident	90.9	Very high	7 Å²	7	35.9 Å²	35.9	4%	0.037	16%	0.158	C	C	.	.			trans	-82.3	142.3	-171.6	-59.7	178.9	0	0	0	113	I148 R149 W152 Q158 V159 Y210	I148-L154 HydrophobicContact CB-CD1 4.43Å; I148-L154 HydrophobicContact CG1-CD1 4.31Å; R149-L154 PolarHBondContact O-N 3.33Å; R149-L154 VanDerWaalsContact O-N 3.17Å; W152-L154 HydrophobicContact CB-CD1 4.46Å; W152-L154 HydrophobicContact CB-CD2 3.69Å; W152-L154 HydrophobicContact CB-CG 3.87Å; W152-L154 HydrophobicContact CE3-CD1 4.37Å; W152-L154 PolarHBondContact O-N 2.91Å; L154-Q158 VanDerWaalsContact CA-OE1 3.29Å; L154-Q158 HydrophobicContact CB-CB 4.06Å; L154-Q158 HydrophobicContact CD2-CB 4.24Å; L154-V159 HydrophobicContact CB-CG2 3.97Å; L154-V159 HydrophobicContact CD1-CG2 4.3Å; L154-Y210 HydrophobicContact CD1-CD2 3.63Å; L154-Y210 HydrophobicContact CD1-CE2 3.74Å; L154-Y210 HydrophobicContact CD2-CD1 4.26Å; L154-Y210 HydrophobicContact CD2-CD2 3.72Å; L154-Y210 HydrophobicContact CD2-CE2 4.07Å; L154-Y210 HydrophobicContact CD2-CG 3.83Å; L154-Y210 HydrophobicContact CG-CD2 4.35Å
155	E	89.3	Confident	91	Very high	102 Å²	102	38.4 Å²	38.4	48%	0.477	17%	0.171	S	C	.	.			trans	-71.7	156.8	166	-67.6	179.9	-152.9	0	0	111.3	W157 Q158 V159	E155-W157 VanDerWaalsContact C-N 3.26Å; E155-W157 PolarHBondContact O-N 3.48Å; E155-W157 VanDerWaalsContact O-N 3.16Å; E155-W157 VanDerWaalsContact OE2-CD1 3.29Å; E155-W157 PolarHBondContact OE2-NE1 3.04Å; E155-Q158 HydrophobicContact CB-CG 4.37Å; E155-Q158 WeakPolarHBondContact O-CA 3.33Å; E155-Q158 VanDerWaalsContact O-CB 3.31Å; E155-Q158 WeakPolarHBondContact O-CB 3.41Å; E155-Q158 PolarHBondContact O-N 2.91Å; E155-V159 PolarHBondContact O-N 2.87Å
156	D	88.1	Confident	91.3	Very high	23 Å²	23	38.4 Å²	38.4	12%	0.123	17%	0.171	C	C	.	.	H	α-helix	trans	-56.1	-37.3	-176.4	-74.1	-40.4	0	0	0	114	R149 Q158 V159 A160 K381 Y405 V522 S525	R149-D156 IonicContact CZ-OD1 2.78Å; R149-D156 IonicContact NE-OD1 3.97Å; R149-D156 IonicContact NH2-OD1 3.68Å; R149-D156 PolarHBondContact NH2-OD1 3.08Å; D156-Q158 VanDerWaalsContact C-N 3.27Å; D156-Q158 PolarHBondContact O-N 3.05Å; D156-V159 PolarHBondContact O-N 3.17Å; D156-A160 PolarHBondContact O-N 3.06Å; D156-K381 VanDerWaalsContact CG-NZ 3.3Å; D156-K381 IonicContact OD1-NZ 3.98Å; D156-K381 PolarHBondContact OD1-NZ 3.19Å; D156-K381 IonicContact OD2-NZ 3.39Å; D156-K381 PolarHBondContact OD2-NZ 2.87Å; D156-Y405 PolarHBondContact OD1-OH 2.85Å; D156-V522 HydrophobicContact CB-CB 4.4Å; D156-V522 HydrophobicContact CB-CG1 4.34Å; D156-V522 HydrophobicContact CB-CG2 4.34Å; D156-S525 WeakPolarHBondContact OD2-CB 3.44Å; D156-S525 PolarHBondContact OD2-OG 3.36Å
157	W	90.9	Very high	91.6	Very high	110 Å²	110	38.6 Å²	38.6	42%	0.417	17%	0.172	S	C	.	.	H	α-helix	trans	-70.3	-25.2	178.1	71.4	-93.5	0	0	0	112.7	E155 L161 F518 V522	E155-W157 VanDerWaalsContact C-N 3.26Å; E155-W157 PolarHBondContact O-N 3.48Å; E155-W157 VanDerWaalsContact O-N 3.16Å; E155-W157 VanDerWaalsContact OE2-CD1 3.29Å; E155-W157 PolarHBondContact OE2-NE1 3.04Å; W157-L161 HydrophobicContact CZ3-CD2 4.07Å; W157-L161 VanDerWaalsContact O-CB 3.24Å; W157-L161 WeakPolarHBondContact O-CB 3.32Å; W157-L161 PolarHBondContact O-N 2.75Å; W157-F518 HydrophobicContact CB-CE1 4.33Å; W157-V522 HydrophobicContact CB-CG1 4.46Å; W157-V522 HydrophobicContact CB-CG2 4.02Å
158	Q	94	Very high	91.7	Very high	39 Å²	39	39.3 Å²	39.3	18%	0.182	18%	0.178	C	C	.	.	H	α-helix	trans	-72.9	-42.3	174.8	-66.3	176.7	-32.2	0	0	110.1	L154 E155 D156 A160 L161 V162 Y210	L154-Q158 VanDerWaalsContact CA-OE1 3.29Å; L154-Q158 HydrophobicContact CB-CB 4.06Å; L154-Q158 HydrophobicContact CD2-CB 4.24Å; E155-Q158 HydrophobicContact CB-CG 4.37Å; E155-Q158 WeakPolarHBondContact O-CA 3.33Å; E155-Q158 VanDerWaalsContact O-CB 3.31Å; E155-Q158 WeakPolarHBondContact O-CB 3.41Å; E155-Q158 PolarHBondContact O-N 2.91Å; D156-Q158 VanDerWaalsContact C-N 3.27Å; D156-Q158 PolarHBondContact O-N 3.05Å; Q158-A160 PolarHBondContact O-N 3.18Å; Q158-L161 PolarHBondContact O-N 3.45Å; Q158-V162 PolarHBondContact O-N 3.28Å; Q158-Y210 VanDerWaalsContact C-OH 3.32Å; Q158-Y210 WeakPolarHBondContact CA-OH 3.45Å; Q158-Y210 HydrophobicContact CB-CE1 4.25Å; Q158-Y210 HydrophobicContact CB-CE2 4.19Å; Q158-Y210 VanDerWaalsContact CB-OH 3.3Å; Q158-Y210 WeakPolarHBondContact CB-OH 3.48Å; Q158-Y210 HydrophobicContact CG-CE1 4.34Å; Q158-Y210 PolarHBondContact O-OH 2.98Å
159	V	91.4	Very high	91.9	Very high	0 Å²	0	39.6 Å²	39.6	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-62.2	-45.2	173.1	-170.2	0	0	0	0	110.7	S145 R149 L154 E155 D156 L161 V162	S145-V159 VanDerWaalsContact OG-CG1 3.31Å; S145-V159 WeakPolarHBondContact OG-CG1 3.21Å; R149-V159 HydrophobicContact CB-CG2 4.05Å; R149-V159 HydrophobicContact CG-CG2 4.34Å; L154-V159 HydrophobicContact CB-CG2 3.97Å; L154-V159 HydrophobicContact CD1-CG2 4.3Å; E155-V159 PolarHBondContact O-N 2.87Å; D156-V159 PolarHBondContact O-N 3.17Å; V159-L161 VanDerWaalsContact C-N 3.33Å; V159-L161 PolarHBondContact O-N 2.81Å; V159-V162 PolarHBondContact O-N 3.23Å
160	A	93.4	Very high	92	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-58.1	-41.6	174.2	0	0	0	0	0	113.1	D156 Q158 V162 S163 T164 P517 F518 Q521 V522	D156-A160 PolarHBondContact O-N 3.06Å; Q158-A160 PolarHBondContact O-N 3.18Å; A160-V162 VanDerWaalsContact C-N 3.34Å; A160-V162 PolarHBondContact O-N 3.49Å; A160-S163 PolarHBondContact O-N 3.15Å; A160-T164 PolarHBondContact O-N 3.08Å; A160-T164 PolarHBondContact O-OG1 3.1Å; A160-P517 HydrophobicContact CB-CB 4.36Å; A160-F518 HydrophobicContact CB-CD1 4.06Å; A160-F518 HydrophobicContact CB-CD2 4.23Å; A160-F518 HydrophobicContact CB-CE1 4.21Å; A160-F518 HydrophobicContact CB-CE2 4.37Å; A160-F518 HydrophobicContact CB-CG 4.07Å; A160-F518 HydrophobicContact CB-CZ 4.36Å; A160-Q521 HydrophobicContact CB-CB 4.23Å; A160-V522 HydrophobicContact CB-CG2 3.73Å
161	L	95.4	Very high	92.2	Very high	41 Å²	41	41.3 Å²	41.3	22%	0.215	19%	0.187	C	C	.	.	H	α-helix	trans	-60.7	-40.1	-178.4	-178.1	63.4	0	0	0	112.1	W157 Q158 V159 S163 T164 M165 I214 F518	W157-L161 HydrophobicContact CZ3-CD2 4.07Å; W157-L161 VanDerWaalsContact O-CB 3.24Å; W157-L161 WeakPolarHBondContact O-CB 3.32Å; W157-L161 PolarHBondContact O-N 2.75Å; Q158-L161 PolarHBondContact O-N 3.45Å; V159-L161 VanDerWaalsContact C-N 3.33Å; V159-L161 PolarHBondContact O-N 2.81Å; L161-S163 VanDerWaalsContact C-N 3.34Å; L161-S163 PolarHBondContact O-N 3.28Å; L161-T164 PolarHBondContact O-N 2.94Å; L161-M165 HydrophobicContact CD1-CE 3.8Å; L161-M165 HydrophobicContact CD1-CG 3.83Å; L161-M165 HydrophobicContact CG-CG 4.11Å; L161-M165 VanDerWaalsContact O-CB 3.23Å; L161-M165 WeakPolarHBondContact O-CB 3.37Å; L161-M165 WeakPolarHBondContact O-CG 3.31Å; L161-M165 PolarHBondContact O-N 3.17Å; L161-I214 HydrophobicContact CD2-CD1 4.21Å; L161-F518 HydrophobicContact CB-CZ 4.43Å; L161-F518 HydrophobicContact CD1-CZ 4.44Å
162	V	94	Very high	92.3	Very high	1 Å²	1	40.8 Å²	40.8	1%	0.006	19%	0.19	C	C	.	.	H	α-helix	trans	-55.2	-52.6	174.2	-180	0	0	0	0	110.2	L141 I148 Q158 V159 A160 T164 M165 V166 Y210 F213 I214 R217	L141-V162 HydrophobicContact CD2-CG1 3.69Å; I148-V162 HydrophobicContact CD1-CG2 4.2Å; Q158-V162 PolarHBondContact O-N 3.28Å; V159-V162 PolarHBondContact O-N 3.23Å; A160-V162 VanDerWaalsContact C-N 3.34Å; A160-V162 PolarHBondContact O-N 3.49Å; V162-T164 PolarHBondContact O-N 3.42Å; V162-M165 PolarHBondContact O-N 3.35Å; V162-V166 PolarHBondContact O-N 3.19Å; V162-Y210 HydrophobicContact CG2-CD2 4.44Å; V162-Y210 HydrophobicContact CG2-CE2 3.66Å; V162-F213 HydrophobicContact CG1-CD1 4Å; V162-F213 HydrophobicContact CG1-CE1 3.6Å; V162-F213 HydrophobicContact CG2-CD1 4.14Å; V162-F213 HydrophobicContact CG2-CE1 4.22Å; V162-I214 HydrophobicContact CG2-CG1 4.07Å; V162-R217 HydrophobicContact CG1-CB 4.4Å; V162-R217 HydrophobicContact CG1-CG 4.3Å
163	S	92.1	Very high	92.4	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-61.9	-46.8	-176.3	-61.2	0	0	0	0	111.6	A160 L161 M165 V166 F167 P517 Q521	A160-S163 PolarHBondContact O-N 3.15Å; L161-S163 VanDerWaalsContact C-N 3.34Å; L161-S163 PolarHBondContact O-N 3.28Å; S163-M165 VanDerWaalsContact C-N 3.34Å; S163-M165 PolarHBondContact O-N 2.94Å; S163-V166 PolarHBondContact O-N 2.87Å; S163-F167 VanDerWaalsContact O-CD2 3.22Å; S163-F167 WeakPolarHBondContact O-CD2 3.26Å; S163-P517 VanDerWaalsContact CB-CG 3.49Å; S163-Q521 PolarHBondContact OG-OE1 2.9Å
164	T	94.6	Very high	92.4	Very high	13 Å²	13	30.8 Å²	30.8	8%	0.08	16%	0.162	C	C	.	.	H	α-helix	trans	-62.5	-39.3	176.4	-63.8	0	0	0	0	112.2	A160 L161 V162 V166 F167 V168 M514 F518	A160-T164 PolarHBondContact O-N 3.08Å; A160-T164 PolarHBondContact O-OG1 3.1Å; L161-T164 PolarHBondContact O-N 2.94Å; V162-T164 PolarHBondContact O-N 3.42Å; T164-V166 VanDerWaalsContact C-N 3.33Å; T164-V166 PolarHBondContact O-N 3.36Å; T164-F167 PolarHBondContact O-N 3.42Å; T164-V168 HydrophobicContact CG2-CG2 4.28Å; T164-V168 WeakPolarHBondContact O-CG2 3.32Å; T164-V168 PolarHBondContact O-N 3.38Å; T164-M514 HydrophobicContact CG2-CB 3.99Å; T164-M514 HydrophobicContact CG2-CG 4.14Å; T164-M514 VanDerWaalsContact CG2-O 3.31Å; T164-M514 WeakPolarHBondContact CG2-O 3.4Å; T164-M514 PolarHBondContact OG1-O 2.99Å; T164-F518 HydrophobicContact CG2-CD2 4.43Å; T164-F518 HydrophobicContact CG2-CE2 4.02Å; T164-F518 VanDerWaalsContact OG1-CD2 3.26Å; T164-F518 WeakPolarHBondContact OG1-CD2 3.4Å; T164-F518 VanDerWaalsContact OG1-CE2 3.31Å; T164-F518 WeakPolarHBondContact OG1-CE2 3.23Å
165	M	95.2	Very high	92.2	Very high	53 Å²	53	35.1 Å²	35.1	26%	0.261	19%	0.188	S	C	.	.	H	α-helix	trans	-67.1	-29.4	-178.9	-76.5	-65.4	123.7	0	0	113.5	L161 V162 S163 V168 G169 I214 S218	L161-M165 HydrophobicContact CD1-CE 3.8Å; L161-M165 HydrophobicContact CD1-CG 3.83Å; L161-M165 HydrophobicContact CG-CG 4.11Å; L161-M165 VanDerWaalsContact O-CB 3.23Å; L161-M165 WeakPolarHBondContact O-CB 3.37Å; L161-M165 WeakPolarHBondContact O-CG 3.31Å; L161-M165 PolarHBondContact O-N 3.17Å; V162-M165 PolarHBondContact O-N 3.35Å; S163-M165 VanDerWaalsContact C-N 3.34Å; S163-M165 PolarHBondContact O-N 2.94Å; M165-V168 HydrophobicContact CE-CB 4.46Å; M165-V168 HydrophobicContact CE-CG2 3.85Å; M165-V168 PolarHBondContact O-N 3.47Å; M165-V168 HydrophobicContact SD-CB 4.43Å; M165-V168 HydrophobicContact SD-CG2 4.44Å; M165-G169 PolarHBondContact O-N 2.89Å; M165-I214 HydrophobicContact CB-CG2 3.84Å; M165-I214 HydrophobicContact CG-CG2 3.76Å; M165-S218 PolarHBondContact O-OG 3.44Å
166	V	94.6	Very high	92.2	Very high	3 Å²	3	35 Å²	35	2%	0.018	19%	0.19	C	C	.	.	H	α-helix	trans	-60.8	-45.7	167.6	177.9	0	0	0	0	110.8	L141 V162 S163 T164 G169 F170 R217 G221	L141-V166 HydrophobicContact CD1-CB 4.34Å; L141-V166 HydrophobicContact CD1-CG2 4.1Å; L141-V166 HydrophobicContact CD2-CG2 4.35Å; V162-V166 PolarHBondContact O-N 3.19Å; S163-V166 PolarHBondContact O-N 2.87Å; T164-V166 VanDerWaalsContact C-N 3.33Å; T164-V166 PolarHBondContact O-N 3.36Å; V166-G169 PolarHBondContact O-N 3.46Å; V166-F170 PolarHBondContact O-N 3.22Å; V166-R217 HydrophobicContact CG2-CB 3.8Å; V166-G221 WeakPolarHBondContact O-CA 3.47Å
167	F	93.4	Very high	92.2	Very high	4 Å²	4	34.3 Å²	34.3	2%	0.018	19%	0.188	C	C	.	.	H	α-helix	trans	-72	-30.5	179	-67.9	-69.9	0	0	0	113.7	I138 S163 T164 F170 M171 Y369 G513 M514	I138-F167 HydrophobicContact CG2-CE1 4.21Å; I138-F167 HydrophobicContact CG2-CZ 3.95Å; S163-F167 VanDerWaalsContact O-CD2 3.22Å; S163-F167 WeakPolarHBondContact O-CD2 3.26Å; T164-F167 PolarHBondContact O-N 3.42Å; F167-F170 WeakPolarHBondContact O-CB 3.01Å; F167-F170 PolarHBondContact O-N 3.47Å; F167-M171 WeakPolarHBondContact O-CB 3.43Å; F167-M171 PolarHBondContact O-N 3.43Å; F167-Y369 HydrophobicContact CE1-CD1 4.47Å; F167-Y369 HydrophobicContact CE1-CD2 4.1Å; F167-Y369 HydrophobicContact CE1-CE1 4.03Å; F167-Y369 AromaticContact CE1-CE2 3.6Å; F167-Y369 HydrophobicContact CE1-CE2 3.6Å; F167-Y369 AromaticContact CE1-CZ 3.56Å; F167-Y369 HydrophobicContact CE2-CG 4.41Å; F167-Y369 AromaticContact CZ-CD1 3.7Å; F167-Y369 HydrophobicContact CZ-CD1 3.7Å; F167-Y369 AromaticContact CZ-CD2 3.8Å; F167-Y369 HydrophobicContact CZ-CD2 3.8Å; F167-Y369 AromaticContact CZ-CE1 3.63Å; F167-Y369 HydrophobicContact CZ-CE1 3.63Å; F167-Y369 AromaticContact CZ-CE2 3.72Å; F167-Y369 HydrophobicContact CZ-CE2 3.72Å; F167-Y369 AromaticContact CZ-CG 3.78Å; F167-Y369 HydrophobicContact CZ-CG 3.78Å; F167-Y369 AromaticContact CZ-CZ 3.63Å; F167-G513 VanDerWaalsContact CD2-C 3.47Å; F167-G513 WeakPolarHBondContact CD2-O 3.38Å; F167-G513 WeakPolarHBondContact CE2-O 3.39Å; F167-M514 HydrophobicContact CB-CB 4.45Å; F167-M514 HydrophobicContact CB-CG 3.49Å; F167-M514 VanDerWaalsContact CB-CG 3.49Å
168	V	93.8	Very high	91.9	Very high	43 Å²	43	29.9 Å²	29.9	26%	0.261	18%	0.177	S	C	.	.	H	α-helix	trans	-62.3	-49.6	169.3	172	0	0	0	0	110	T164 M165 F170 M171 V172 M514	T164-V168 HydrophobicContact CG2-CG2 4.28Å; T164-V168 WeakPolarHBondContact O-CG2 3.32Å; T164-V168 PolarHBondContact O-N 3.38Å; M165-V168 HydrophobicContact CE-CB 4.46Å; M165-V168 HydrophobicContact CE-CG2 3.85Å; M165-V168 PolarHBondContact O-N 3.47Å; M165-V168 HydrophobicContact SD-CB 4.43Å; M165-V168 HydrophobicContact SD-CG2 4.44Å; V168-F170 VanDerWaalsContact C-N 3.31Å; V168-F170 PolarHBondContact O-N 3.29Å; V168-M171 PolarHBondContact O-N 3.46Å; V168-V172 HydrophobicContact CG1-CG2 4.4Å; V168-V172 WeakPolarHBondContact O-CG2 3.37Å; V168-V172 PolarHBondContact O-N 3.44Å; V168-M514 HydrophobicContact CB-SD 4.34Å; V168-M514 HydrophobicContact CG2-CG 4.08Å; V168-M514 HydrophobicContact CG2-SD 3.47Å; V168-M514 WeakPolarHBondContact CG2-SD 3.43Å
169	G	94.1	Very high	91.4	Very high	8 Å²	8	34.7 Å²	34.7	8%	0.082	19%	0.194	C	C	.	.	H	α-helix	trans	-55.4	-46.3	174	0	0	0	0	0	111.8	M165 V166 M171 C173 C222	M165-G169 PolarHBondContact O-N 2.89Å; V166-G169 PolarHBondContact O-N 3.46Å; G169-M171 PolarHBondContact O-N 2.85Å; G169-C173 VanDerWaalsContact O-CB 3.27Å; G169-C173 WeakPolarHBondContact O-CB 3.07Å; G169-C173 PolarHBondContact O-N 2.91Å; G169-C222 PolarHBondContact O-SG 3.2Å
170	F	92.6	Very high	91.3	Very high	6 Å²	6	38.1 Å²	38.1	3%	0.026	21%	0.211	C	C	.	.	H	α-helix	trans	-54.9	-54.9	174.2	-158.8	141.3	0	0	0	111.1	I138 V166 F167 V168 G174 G221 V224 A225 R510	I138-F170 HydrophobicContact CD1-CE1 4.25Å; V166-F170 PolarHBondContact O-N 3.22Å; F167-F170 WeakPolarHBondContact O-CB 3.01Å; F167-F170 PolarHBondContact O-N 3.47Å; V168-F170 VanDerWaalsContact C-N 3.31Å; V168-F170 PolarHBondContact O-N 3.29Å; F170-G174 WeakPolarHBondContact O-CA 3.49Å; F170-G174 PolarHBondContact O-N 2.84Å; F170-G221 WeakPolarHBondContact CA-O 3.47Å; F170-V224 HydrophobicContact CD1-CB 4.49Å; F170-V224 HydrophobicContact CD1-CG1 3.9Å; F170-V224 HydrophobicContact CE1-CB 4.41Å; F170-V224 HydrophobicContact CE1-CG1 3.44Å; F170-V224 VanDerWaalsContact CE1-CG1 3.44Å; F170-V224 HydrophobicContact CZ-CG1 4.06Å; F170-A225 HydrophobicContact CD2-CB 3.78Å; F170-A225 HydrophobicContact CE2-CB 4.1Å; F170-A225 HydrophobicContact CG-CB 4.41Å; F170-A225 WeakPolarHBondContact O-CB 3.28Å; F170-R510 VanDerWaalsContact CE1-CZ 3.44Å
171	M	90.7	Very high	90.9	Very high	63 Å²	63	38.1 Å²	38.1	31%	0.31	21%	0.211	S	C	.	.	H	α-helix	trans	-61.6	-50	-174.7	-177.5	179.6	64.4	0	0	112.4	F167 V168 G169 G174 R510 I511 M514	F167-M171 WeakPolarHBondContact O-CB 3.43Å; F167-M171 PolarHBondContact O-N 3.43Å; V168-M171 PolarHBondContact O-N 3.46Å; G169-M171 PolarHBondContact O-N 2.85Å; M171-G174 PolarHBondContact O-N 3.21Å; M171-R510 HydrophobicContact CB-CB 4.17Å; M171-I511 HydrophobicContact SD-CG1 4.34Å; M171-M514 HydrophobicContact CB-CE 3.96Å; M171-M514 HydrophobicContact CE-CE 3.49Å; M171-M514 VanDerWaalsContact CE-CE 3.49Å; M171-M514 HydrophobicContact CE-SD 4.16Å; M171-M514 HydrophobicContact CG-CE 4.26Å; M171-M514 HydrophobicContact SD-CE 3.38Å; M171-M514 WeakPolarHBondContact SD-CE 3.45Å
172	V	91.5	Very high	90.4	Very high	83 Å²	83	39.6 Å²	39.6	50%	0.503	22%	0.22	S	C	.	.	H	α-helix	trans	-63.7	-49.4	-177.1	174.9	0	0	0	0	110.6	V168 G174	V168-V172 HydrophobicContact CG1-CG2 4.4Å; V168-V172 WeakPolarHBondContact O-CG2 3.37Å; V168-V172 PolarHBondContact O-N 3.44Å; V172-G174 VanDerWaalsContact C-N 3.32Å; V172-G174 PolarHBondContact O-N 3.07Å
173	C	92.8	Very high	89.8	Confident	30 Å²	30	46.5 Å²	46.5	20%	0.203	25%	0.246	C	C	.	.	H	α-helix	trans	-75	-19.1	-179.9	-71.7	0	0	0	0	113.2	G169 L176 A177 C222 A225	G169-C173 VanDerWaalsContact O-CB 3.27Å; G169-C173 WeakPolarHBondContact O-CB 3.07Å; G169-C173 PolarHBondContact O-N 2.91Å; C173-L176 PolarHBondContact O-N 2.04Å; C173-A177 WeakPolarHBondContact O-CB 3.4Å; C173-A177 PolarHBondContact O-N 3.43Å; C173-C222 HydrophobicContact CB-CB 3.5Å; C173-C222 VanDerWaalsContact CB-CB 3.5Å; C173-C222 WeakPolarHBondContact CB-SG 3.07Å; C173-C222 WeakPolarHBondContact SG-CB 3.5Å; C173-C222 CovalentContact SG-SG 2.04Å; C173-C222 PolarHBondContact SG-SG 3.11Å; C173-A225 HydrophobicContact CB-CB 4.1Å
174	G	88.3	Confident	89.5	Confident	17 Å²	17	52.4 Å²	52.4	18%	0.175	27%	0.269	C	S	.	.	H	α-helix	trans	-68.7	-39.9	178	0	0	0	0	0	113.5	F170 M171 V172 A177 G178	F170-G174 WeakPolarHBondContact O-CA 3.49Å; F170-G174 PolarHBondContact O-N 2.84Å; M171-G174 PolarHBondContact O-N 3.21Å; V172-G174 VanDerWaalsContact C-N 3.32Å; V172-G174 PolarHBondContact O-N 3.07Å; G174-A177 PolarHBondContact O-N 3.31Å; G174-G178 PolarHBondContact O-N 3.38Å
175	V	86.3	Confident	89.1	Confident	98 Å²	98	51.8 Å²	51.8	59%	0.594	27%	0.265	S	S	*	.	H	α-helix	trans	-63.9	-44.4	173.7	179.7	0	0	0	0	110.4	Y179	V175-Y179 PolarHBondContact O-N 3.37Å; V175-Y179 VanDerWaalsContact O-N 3.14Å
176	L	88.8	Confident	88.8	Confident	99 Å²	99	50.7 Å²	50.7	52%	0.518	26%	0.258	S	S	.	.	H	α-helix	trans	-64.7	-45.8	176.4	-64.1	174	0	0	0	111.8	C173 G178 Y179 I180	C173-L176 PolarHBondContact O-N 2.04Å; L176-G178 VanDerWaalsContact C-N 3.35Å; L176-G178 PolarHBondContact O-N 3.42Å; L176-Y179 PolarHBondContact O-N 3.28Å; L176-I180 WeakPolarHBondContact O-CB 3.34Å; L176-I180 WeakPolarHBondContact O-CD1 3.31Å; L176-I180 WeakPolarHBondContact O-CG1 3.08Å; L176-I180 PolarHBondContact O-N 3.38Å
177	A	88.7	Confident	88.6	Confident	10 Å²	10	53.4 Å²	53.4	8%	0.083	27%	0.268	C	S	.	.	H	α-helix	trans	-61	-41.5	178.5	0	0	0	0	0	111.7	C173 G174 I180 A181 V189 Q229	C173-A177 WeakPolarHBondContact O-CB 3.4Å; C173-A177 PolarHBondContact O-N 3.43Å; G174-A177 PolarHBondContact O-N 3.31Å; A177-I180 PolarHBondContact O-N 3.02Å; A177-A181 WeakPolarHBondContact O-CB 3.33Å; A177-A181 PolarHBondContact O-N 2.54Å; A177-V189 HydrophobicContact CB-CG1 3.93Å; A177-Q229 HydrophobicContact CB-CG 4.48Å
178	G	84.4	Confident	88.5	Confident	17 Å²	17	58.2 Å²	58.2	18%	0.175	29%	0.289	C	S	.	.	H	α-helix	trans	-60.1	-49.9	173.5	0	0	0	0	0	112.5	G174 L176 I180 A181 D182	G174-G178 PolarHBondContact O-N 3.38Å; L176-G178 VanDerWaalsContact C-N 3.35Å; L176-G178 PolarHBondContact O-N 3.42Å; G178-I180 PolarHBondContact O-N 3.04Å; G178-A181 PolarHBondContact O-N 3.17Å; G178-D182 PolarHBondContact O-N 3.44Å
179	Y	84.2	Confident	88.4	Confident	140 Å²	140	57 Å²	57	55%	0.549	28%	0.282	S	S	.	.	H	α-helix	trans	-60.1	-44.1	176.9	176.1	-95.3	0	0	0	112.8	V175 L176 R183	V175-Y179 PolarHBondContact O-N 3.37Å; V175-Y179 VanDerWaalsContact O-N 3.14Å; L176-Y179 PolarHBondContact O-N 3.28Å; Y179-R183 WeakPolarHBondContact O-CB 3.3Å; Y179-R183 PolarHBondContact O-N 3.49Å; Y179-R183 PolarHBondContact OH-NH1 2.97Å
180	I	88.4	Confident	88.3	Confident	71 Å²	71	56.7 Å²	56.7	36%	0.364	28%	0.278	S	S	.	.	H	α-helix	trans	-67.4	-38.5	178.2	-64.9	165.9	0	0	0	110.3	L176 A177 G178 R183 Y184 V189	L176-I180 WeakPolarHBondContact O-CB 3.34Å; L176-I180 WeakPolarHBondContact O-CD1 3.31Å; L176-I180 WeakPolarHBondContact O-CG1 3.08Å; L176-I180 PolarHBondContact O-N 3.38Å; A177-I180 PolarHBondContact O-N 3.02Å; G178-I180 PolarHBondContact O-N 3.04Å; I180-R183 PolarHBondContact O-N 3.06Å; I180-Y184 HydrophobicContact CG2-CD2 3.84Å; I180-Y184 WeakPolarHBondContact O-CB 3.49Å; I180-Y184 PolarHBondContact O-N 2.78Å; I180-V189 HydrophobicContact CB-CG2 4.09Å; I180-V189 HydrophobicContact CG2-CG2 3.55Å
181	A	86.2	Confident	88.4	Confident	0 Å²	0	59.4 Å²	59.4	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-65.6	-42.9	-179.4	0	0	0	0	0	111.6	A177 G178 R183 G185 R186 V189 Q229	A177-A181 WeakPolarHBondContact O-CB 3.33Å; A177-A181 PolarHBondContact O-N 2.54Å; G178-A181 PolarHBondContact O-N 3.17Å; A181-R183 VanDerWaalsContact C-N 3.29Å; A181-R183 PolarHBondContact O-N 3.37Å; A181-G185 CarbonylContact O-C 3.54Å; A181-G185 VanDerWaalsContact O-C 3.24Å; A181-G185 WeakPolarHBondContact O-CA 3.14Å; A181-G185 PolarHBondContact O-N 2.77Å; A181-R186 HydrophobicContact CB-CG 4.24Å; A181-R186 PolarHBondContact O-N 3.04Å; A181-V189 HydrophobicContact CB-CB 3.99Å; A181-V189 HydrophobicContact CB-CG1 4.25Å; A181-V189 HydrophobicContact CB-CG2 3.87Å; A181-Q229 HydrophobicContact CB-CG 4.43Å
182	D	83.1	Confident	88.5	Confident	73 Å²	73	58 Å²	58	39%	0.39	29%	0.292	S	S	.	.	H	α-helix	trans	-68.1	-26.4	176.6	-72.3	-5	0	0	0	112.7	G178 R186	G178-D182 PolarHBondContact O-N 3.44Å; D182-R186 IonicContact OD1-CZ 3.46Å; D182-R186 VanDerWaalsContact OD1-CZ 3.25Å; D182-R186 IonicContact OD1-NH1 3.49Å; D182-R186 PolarHBondContact OD1-NH1 3.27Å; D182-R186 IonicContact OD1-NH2 2.72Å; D182-R186 PolarHBondContact OD1-NH2 2.98Å
183	R	82.6	Confident	88.6	Confident	146 Å²	146	54.4 Å²	54.4	55%	0.551	27%	0.271	S	S	*	.	H	α-helix	trans	-92	-42.8	-179.3	-172.9	170.4	-178.1	166.1	-0.7	113.8	Y179 I180 A181 Y301	Y179-R183 WeakPolarHBondContact O-CB 3.3Å; Y179-R183 PolarHBondContact O-N 3.49Å; Y179-R183 PolarHBondContact OH-NH1 2.97Å; I180-R183 PolarHBondContact O-N 3.06Å; A181-R183 VanDerWaalsContact C-N 3.29Å; A181-R183 PolarHBondContact O-N 3.37Å; R183-Y301 PolarHBondContact O-OH 3.31Å; R183-Y301 VanDerWaalsContact O-OH 3.07Å
184	Y	86.1	Confident	88.6	Confident	123 Å²	123	53 Å²	53	48%	0.482	26%	0.262	S	S	.	.	H	α-helix	trans	-108.9	-12.7	-170.5	-67	-82.5	0	0	0	114.6	I180 K188 Y301	I180-Y184 HydrophobicContact CG2-CD2 3.84Å; I180-Y184 WeakPolarHBondContact O-CB 3.49Å; I180-Y184 PolarHBondContact O-N 2.78Å; Y184-K188 WeakPolarHBondContact O-CD 3.27Å; Y184-K188 WeakPolarHBondContact O-CE 3.44Å; Y184-K188 PolarHBondContact O-NZ 2.71Å; Y184-Y301 PolarHBondContact O-OH 3.35Å
185	G	85.7	Confident	88.9	Confident	0 Å²	0	55.2 Å²	55.2	0%	0	27%	0.272	C	S	.	.			trans	116.8	134.1	179.1	0	0	0	0	0	112.2	A181 K188 V189 E297 Y301	A181-G185 CarbonylContact O-C 3.54Å; A181-G185 VanDerWaalsContact O-C 3.24Å; A181-G185 WeakPolarHBondContact O-CA 3.14Å; A181-G185 PolarHBondContact O-N 2.77Å; G185-K188 PolarHBondContact O-N 3.17Å; G185-V189 PolarHBondContact O-N 3.3Å; G185-E297 VanDerWaalsContact C-OE2 3.3Å; G185-E297 WeakPolarHBondContact CA-OE2 3.35Å; G185-Y301 VanDerWaalsContact CA-CZ 3.43Å; G185-Y301 VanDerWaalsContact N-CZ 3.33Å; G185-Y301 PolarHBondContact N-OH 3.17Å
186	R	87.8	Confident	89.4	Confident	30 Å²	30	56.2 Å²	56.2	11%	0.113	27%	0.265	C	S	.	.	H	α-helix	trans	-65.1	-42.4	-176.6	-66.6	-159.2	-173.2	-62.4	-18	111.6	A181 D182 K188 V189 V190 L233 E236 E297	A181-R186 HydrophobicContact CB-CG 4.24Å; A181-R186 PolarHBondContact O-N 3.04Å; D182-R186 IonicContact OD1-CZ 3.46Å; D182-R186 VanDerWaalsContact OD1-CZ 3.25Å; D182-R186 IonicContact OD1-NH1 3.49Å; D182-R186 PolarHBondContact OD1-NH1 3.27Å; D182-R186 IonicContact OD1-NH2 2.72Å; D182-R186 PolarHBondContact OD1-NH2 2.98Å; R186-K188 VanDerWaalsContact C-N 3.27Å; R186-K188 PolarHBondContact O-N 2.75Å; R186-V189 PolarHBondContact O-N 2.98Å; R186-V190 WeakPolarHBondContact O-CG2 3.37Å; R186-V190 PolarHBondContact O-N 3.13Å; R186-L233 HydrophobicContact CB-CB 4.41Å; R186-L233 HydrophobicContact CB-CD1 4.11Å; R186-E236 WeakPolarHBondContact CD-OE1 3.41Å; R186-E236 IonicContact CZ-OE1 3.42Å; R186-E236 IonicContact NE-OE1 3.32Å; R186-E236 PolarHBondContact NE-OE1 3.39Å; R186-E236 IonicContact NH2-OE1 2.8Å; R186-E297 PolarHBondContact N-OE1 3.23Å
187	W	90.6	Very high	89.7	Confident	61 Å²	61	51.7 Å²	51.7	23%	0.231	24%	0.241	C	C	.	.	H	α-helix	trans	-57.1	-41	-179.6	174	93	0	0	0	111.9	V190 F191 L233 F292 I295 E297	W187-V190 PolarHBondContact O-N 3.14Å; W187-F191 VanDerWaalsContact O-CB 3.31Å; W187-F191 WeakPolarHBondContact O-CB 3.44Å; W187-F191 PolarHBondContact O-N 3.4Å; W187-L233 HydrophobicContact CB-CD2 4.25Å; W187-F292 PolarHBondContact NE1-O 3.46Å; W187-F292 VanDerWaalsContact NE1-O 3.17Å; W187-I295 PolarHBondContact NE1-O 3.33Å; W187-E297 HydrophobicContact CB-CB 4.38Å; W187-E297 WeakPolarHBondContact CB-OE1 3.42Å; W187-E297 WeakPolarHBondContact CB-OE2 3.32Å; W187-E297 PolarHBondContact N-OE1 2.94Å; W187-E297 PolarHBondContact N-OE2 3.48Å
188	K	92.1	Very high	90	Very high	105 Å²	105	51.6 Å²	51.6	46%	0.457	24%	0.241	S	C	.	.	H	α-helix	trans	-65.5	-41	179.6	-61.4	-178.6	-163.8	152.1	0	113	Y184 G185 R186 G192	Y184-K188 WeakPolarHBondContact O-CD 3.27Å; Y184-K188 WeakPolarHBondContact O-CE 3.44Å; Y184-K188 PolarHBondContact O-NZ 2.71Å; G185-K188 PolarHBondContact O-N 3.17Å; R186-K188 VanDerWaalsContact C-N 3.27Å; R186-K188 PolarHBondContact O-N 2.75Å; K188-G192 PolarHBondContact O-N 2.71Å
189	V	92.4	Very high	90.6	Very high	18 Å²	18	57.1 Å²	57.1	11%	0.109	26%	0.257	C	S	.	.	H	α-helix	trans	-69.3	-40	179.1	172.4	0	0	0	0	111.3	A177 I180 A181 G185 R186 G193 Q229	A177-V189 HydrophobicContact CB-CG1 3.93Å; I180-V189 HydrophobicContact CB-CG2 4.09Å; I180-V189 HydrophobicContact CG2-CG2 3.55Å; A181-V189 HydrophobicContact CB-CB 3.99Å; A181-V189 HydrophobicContact CB-CG1 4.25Å; A181-V189 HydrophobicContact CB-CG2 3.87Å; G185-V189 PolarHBondContact O-N 3.3Å; R186-V189 PolarHBondContact O-N 2.98Å; V189-G193 PolarHBondContact O-N 3.24Å; V189-Q229 HydrophobicContact CG1-CG 4.15Å
190	V	91.7	Very high	91.3	Very high	0 Å²	0	51.7 Å²	51.7	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-63.3	-51.4	174.7	178.4	0	0	0	0	110.3	M127 R186 W187 G192 G193 Y194 Q229 G230 F292	M127-V190 HydrophobicContact CE-CG1 4.24Å; R186-V190 WeakPolarHBondContact O-CG2 3.37Å; R186-V190 PolarHBondContact O-N 3.13Å; W187-V190 PolarHBondContact O-N 3.14Å; V190-G192 PolarHBondContact O-N 3.36Å; V190-G193 PolarHBondContact O-N 3.01Å; V190-Y194 HydrophobicContact CG1-CD2 4.03Å; V190-Y194 HydrophobicContact CG1-CE2 3.92Å; V190-Y194 VanDerWaalsContact O-CD2 3.29Å; V190-Y194 WeakPolarHBondContact O-CD2 3.47Å; V190-Y194 PolarHBondContact O-N 2.91Å; V190-Q229 HydrophobicContact CG2-CB 3.8Å; V190-G230 VanDerWaalsContact CG2-N 3.27Å; V190-F292 HydrophobicContact CB-CE1 4.47Å; V190-F292 HydrophobicContact CG1-CE1 3.6Å; V190-F292 HydrophobicContact CG1-CZ 3.59Å
191	F	93.8	Very high	91.6	Very high	63 Å²	63	48.4 Å²	48.4	28%	0.276	22%	0.22	S	C	.	.	H	α-helix	trans	-59.6	-45.5	178.3	178.7	-100.7	0	0	0	112.6	W187 G193 Y194 V195 I289 F292	W187-F191 VanDerWaalsContact O-CB 3.31Å; W187-F191 WeakPolarHBondContact O-CB 3.44Å; W187-F191 PolarHBondContact O-N 3.4Å; F191-G193 VanDerWaalsContact C-N 3.33Å; F191-G193 PolarHBondContact O-N 3.21Å; F191-Y194 WeakPolarHBondContact O-CB 3.45Å; F191-Y194 PolarHBondContact O-N 3.3Å; F191-V195 HydrophobicContact CE1-CG2 4.08Å; F191-V195 HydrophobicContact CE2-CG2 4.47Å; F191-V195 HydrophobicContact CZ-CG2 4.05Å; F191-V195 PolarHBondContact O-N 3.08Å; F191-V195 VanDerWaalsContact O-N 3.11Å; F191-I289 HydrophobicContact CE2-CG2 3.89Å; F191-I289 HydrophobicContact CZ-CG2 4.16Å; F191-F292 HydrophobicContact CD2-CB 3.67Å; F191-F292 HydrophobicContact CD2-CG 4.06Å; F191-F292 HydrophobicContact CE2-CB 4.18Å
192	G	93.9	Very high	92.1	Very high	35 Å²	35	51.9 Å²	51.9	36%	0.361	24%	0.238	S	C	.	.	H	α-helix	trans	-61.3	-40.6	174.9	0	0	0	0	0	112.5	K188 V190 Y194 V195 W196	K188-G192 PolarHBondContact O-N 2.71Å; V190-G192 PolarHBondContact O-N 3.36Å; G192-Y194 VanDerWaalsContact C-N 3.34Å; G192-Y194 PolarHBondContact O-N 2.95Å; G192-V195 PolarHBondContact O-N 3.03Å; G192-W196 VanDerWaalsContact O-CB 3.23Å; G192-W196 WeakPolarHBondContact O-CB 3.47Å; G192-W196 PolarHBondContact O-N 2.87Å
193	G	93.5	Very high	92.8	Very high	6 Å²	6	51 Å²	51	6%	0.062	23%	0.233	C	C	.	.	H	α-helix	trans	-59.9	-40.2	173.5	0	0	0	0	0	113	V189 V190 F191 S197 G223	V189-G193 PolarHBondContact O-N 3.24Å; V190-G193 PolarHBondContact O-N 3.01Å; F191-G193 VanDerWaalsContact C-N 3.33Å; F191-G193 PolarHBondContact O-N 3.21Å; G193-S197 VanDerWaalsContact O-CB 3.22Å; G193-S197 WeakPolarHBondContact O-CB 3.35Å; G193-S197 PolarHBondContact O-N 3.13Å; G193-G223 WeakPolarHBondContact CA-O 3.45Å
194	Y	92.2	Very high	93.5	Very high	2 Å²	2	44.1 Å²	44.1	1%	0.008	21%	0.207	C	C	.	.	H	α-helix	trans	-61.5	-51.4	173.7	-92.1	-76.4	0	0	0	112.9	A130 V133 V190 F191 G192 W196 S197 A198 V227 L288 F292	A130-Y194 WeakPolarHBondContact CA-OH 3.5Å; A130-Y194 HydrophobicContact CB-CE2 4.09Å; A130-Y194 WeakPolarHBondContact CB-OH 3.38Å; A130-Y194 PolarHBondContact O-OH 3.07Å; V133-Y194 HydrophobicContact CB-CE1 4.04Å; V133-Y194 HydrophobicContact CG1-CD1 4.47Å; V133-Y194 HydrophobicContact CG1-CE1 3.81Å; V190-Y194 HydrophobicContact CG1-CD2 4.03Å; V190-Y194 HydrophobicContact CG1-CE2 3.92Å; V190-Y194 VanDerWaalsContact O-CD2 3.29Å; V190-Y194 WeakPolarHBondContact O-CD2 3.47Å; V190-Y194 PolarHBondContact O-N 2.91Å; F191-Y194 WeakPolarHBondContact O-CB 3.45Å; F191-Y194 PolarHBondContact O-N 3.3Å; G192-Y194 VanDerWaalsContact C-N 3.34Å; G192-Y194 PolarHBondContact O-N 2.95Å; Y194-W196 VanDerWaalsContact C-N 3.32Å; Y194-W196 PolarHBondContact O-N 3.34Å; Y194-S197 PolarHBondContact O-N 3.37Å; Y194-A198 VanDerWaalsContact O-CB 3.29Å; Y194-A198 WeakPolarHBondContact O-CB 3.41Å; Y194-A198 PolarHBondContact O-N 3.02Å; Y194-V227 HydrophobicContact CD1-CG2 4.37Å; Y194-V227 HydrophobicContact CD2-CG2 3.81Å; Y194-V227 HydrophobicContact CE1-CG2 4.23Å; Y194-V227 HydrophobicContact CE2-CB 4.08Å; Y194-V227 HydrophobicContact CE2-CG1 3.66Å; Y194-V227 HydrophobicContact CE2-CG2 3.62Å; Y194-V227 HydrophobicContact CG-CG2 4.11Å; Y194-V227 WeakPolarHBondContact OH-CG1 3.23Å; Y194-L288 HydrophobicContact CD1-CD1 4.42Å; Y194-L288 HydrophobicContact CE1-CD1 3.73Å; Y194-F292 HydrophobicContact CD1-CE2 4.36Å; Y194-F292 HydrophobicContact CD2-CD2 4.24Å; Y194-F292 AromaticContact CD2-CE2 3.27Å; Y194-F292 HydrophobicContact CD2-CE2 3.27Å; Y194-F292 AromaticContact CD2-CZ 3.47Å; Y194-F292 HydrophobicContact CD2-CZ 3.47Å; Y194-F292 VanDerWaalsContact CD2-CZ 3.47Å; Y194-F292 AromaticContact CE2-CE2 3.53Å; Y194-F292 HydrophobicContact CE2-CE2 3.53Å; Y194-F292 AromaticContact CE2-CZ 3.47Å; Y194-F292 HydrophobicContact CE2-CZ 3.47Å; Y194-F292 VanDerWaalsContact CE2-CZ 3.47Å; Y194-F292 HydrophobicContact CG-CD2 4.49Å; Y194-F292 AromaticContact CG-CE2 3.8Å; Y194-F292 HydrophobicContact CG-CE2 3.8Å; Y194-F292 HydrophobicContact CG-CZ 4.42Å
195	V	95.5	Very high	94	Very high	63 Å²	63	38.3 Å²	38.3	38%	0.382	18%	0.184	S	C	.	.	H	α-helix	trans	-61.6	-43.7	179.6	176.4	0	0	0	0	110.5	F191 G192 Y199 I289	F191-V195 HydrophobicContact CE1-CG2 4.08Å; F191-V195 HydrophobicContact CE2-CG2 4.47Å; F191-V195 HydrophobicContact CZ-CG2 4.05Å; F191-V195 PolarHBondContact O-N 3.08Å; F191-V195 VanDerWaalsContact O-N 3.11Å; G192-V195 PolarHBondContact O-N 3.03Å; V195-Y199 VanDerWaalsContact O-CB 3.26Å; V195-Y199 WeakPolarHBondContact O-CB 3.38Å; V195-Y199 PolarHBondContact O-N 2.75Å; V195-I289 HydrophobicContact CG2-CD1 4Å; V195-I289 HydrophobicContact CG2-CG1 4.12Å; V195-I289 HydrophobicContact CG2-CG2 4.29Å
196	W	96.1	Very high	94.5	Very high	118 Å²	118	44.1 Å²	44.1	45%	0.447	21%	0.21	S	C	.	.	H	α-helix	trans	-62.9	-51	177.5	-171.7	-80.1	0	0	0	112	G192 Y194 A198 Y199 F200 M219	G192-W196 VanDerWaalsContact O-CB 3.23Å; G192-W196 WeakPolarHBondContact O-CB 3.47Å; G192-W196 PolarHBondContact O-N 2.87Å; Y194-W196 VanDerWaalsContact C-N 3.32Å; Y194-W196 PolarHBondContact O-N 3.34Å; W196-A198 PolarHBondContact O-N 2.76Å; W196-Y199 PolarHBondContact O-N 3.41Å; W196-F200 AromaticContact CD1-CD2 3.63Å; W196-F200 AromaticContact CD2-CD2 3.93Å; W196-F200 HydrophobicContact CD2-CD2 3.93Å; W196-F200 AromaticContact CD2-CE2 3.64Å; W196-F200 HydrophobicContact CD2-CE2 3.64Å; W196-F200 AromaticContact CE2-CD2 3.62Å; W196-F200 AromaticContact CE2-CE2 3.26Å; W196-F200 HydrophobicContact CE3-CE2 4.08Å; W196-F200 AromaticContact CG-CD2 3.97Å; W196-F200 HydrophobicContact CG-CD2 3.97Å; W196-F200 HydrophobicContact CG-CE2 4.18Å; W196-F200 AromaticContact CH2-CE2 3.87Å; W196-F200 HydrophobicContact CH2-CE2 3.87Å; W196-F200 HydrophobicContact CH2-CZ 4.29Å; W196-F200 HydrophobicContact CZ2-CD2 4.18Å; W196-F200 AromaticContact CZ2-CE2 3.41Å; W196-F200 HydrophobicContact CZ2-CE2 3.41Å; W196-F200 VanDerWaalsContact CZ2-CE2 3.41Å; W196-F200 AromaticContact CZ2-CZ 3.95Å; W196-F200 HydrophobicContact CZ2-CZ 3.95Å; W196-F200 HydrophobicContact CZ3-CE2 4.18Å; W196-F200 AromaticContact NE1-CD2 3.42Å; W196-F200 AromaticContact NE1-CE2 3.59Å; W196-F200 WeakPolarHBondContact O-CD2 3.37Å; W196-F200 PolarHBondContact O-N 3.02Å; W196-M219 HydrophobicContact CZ2-SD 4.03Å; W196-M219 PolarHBondContact NE1-O 3.07Å
197	S	95.3	Very high	94.9	Very high	4 Å²	4	42.8 Å²	42.8	3%	0.028	21%	0.205	C	C	.	.	H	α-helix	trans	-60.7	-46.7	180	-163.9	0	0	0	0	111.5	G193 Y194 Y199 S201	G193-S197 VanDerWaalsContact O-CB 3.22Å; G193-S197 WeakPolarHBondContact O-CB 3.35Å; G193-S197 PolarHBondContact O-N 3.13Å; Y194-S197 PolarHBondContact O-N 3.37Å; S197-Y199 PolarHBondContact O-N 2.87Å; S197-S201 WeakPolarHBondContact O-CB 3.48Å; S197-S201 PolarHBondContact O-N 2.78Å
198	A	95.4	Very high	95.1	Very high	8 Å²	8	44.1 Å²	44.1	7%	0.066	22%	0.222	C	C	.	.	H	α-helix	trans	-62.1	-41.2	178.3	0	0	0	0	0	112.4	Y194 W196 L202 I282 I289	Y194-A198 VanDerWaalsContact O-CB 3.29Å; Y194-A198 WeakPolarHBondContact O-CB 3.41Å; Y194-A198 PolarHBondContact O-N 3.02Å; W196-A198 PolarHBondContact O-N 2.76Å; A198-L202 WeakPolarHBondContact O-CB 3.47Å; A198-L202 PolarHBondContact O-N 3.19Å; A198-I282 HydrophobicContact CB-CG2 3.97Å; A198-I289 HydrophobicContact CB-CD1 4.27Å
199	Y	96.8	Very high	95.2	Very high	133 Å²	133	42.5 Å²	42.5	52%	0.522	22%	0.221	S	C	.	.	H	α-helix	trans	-65.6	-50.8	178.3	175.6	-105.3	0	0	0	112.5	V195 W196 S197 S201 L202 L203	V195-Y199 VanDerWaalsContact O-CB 3.26Å; V195-Y199 WeakPolarHBondContact O-CB 3.38Å; V195-Y199 PolarHBondContact O-N 2.75Å; W196-Y199 PolarHBondContact O-N 3.41Å; S197-Y199 PolarHBondContact O-N 2.87Å; Y199-S201 PolarHBondContact O-N 3.01Å; Y199-L202 WeakPolarHBondContact O-CB 3.29Å; Y199-L202 PolarHBondContact O-N 3.48Å; Y199-L203 HydrophobicContact CD1-CD1 4.1Å; Y199-L203 HydrophobicContact CE1-CD1 3.5Å; Y199-L203 HydrophobicContact CE1-CG 4.39Å; Y199-L203 HydrophobicContact CE2-CD1 4.3Å; Y199-L203 HydrophobicContact CE2-CG 4.47Å; Y199-L203 WeakPolarHBondContact O-CG 3.36Å; Y199-L203 PolarHBondContact O-N 3.48Å
200	F	97.5	Very high	95.3	Very high	26 Å²	26	43.4 Å²	43.4	11%	0.114	22%	0.223	C	C	.	.	H	α-helix	trans	-71.5	-29.7	-179.7	-78.4	-76.3	0	0	0	113	W196 L203 T204 L216 M219 V220	W196-F200 AromaticContact CD1-CD2 3.63Å; W196-F200 AromaticContact CD2-CD2 3.93Å; W196-F200 HydrophobicContact CD2-CD2 3.93Å; W196-F200 AromaticContact CD2-CE2 3.64Å; W196-F200 HydrophobicContact CD2-CE2 3.64Å; W196-F200 AromaticContact CE2-CD2 3.62Å; W196-F200 AromaticContact CE2-CE2 3.26Å; W196-F200 HydrophobicContact CE3-CE2 4.08Å; W196-F200 AromaticContact CG-CD2 3.97Å; W196-F200 HydrophobicContact CG-CD2 3.97Å; W196-F200 HydrophobicContact CG-CE2 4.18Å; W196-F200 AromaticContact CH2-CE2 3.87Å; W196-F200 HydrophobicContact CH2-CE2 3.87Å; W196-F200 HydrophobicContact CH2-CZ 4.29Å; W196-F200 HydrophobicContact CZ2-CD2 4.18Å; W196-F200 AromaticContact CZ2-CE2 3.41Å; W196-F200 HydrophobicContact CZ2-CE2 3.41Å; W196-F200 VanDerWaalsContact CZ2-CE2 3.41Å; W196-F200 AromaticContact CZ2-CZ 3.95Å; W196-F200 HydrophobicContact CZ2-CZ 3.95Å; W196-F200 HydrophobicContact CZ3-CE2 4.18Å; W196-F200 AromaticContact NE1-CD2 3.42Å; W196-F200 AromaticContact NE1-CE2 3.59Å; W196-F200 WeakPolarHBondContact O-CD2 3.37Å; W196-F200 PolarHBondContact O-N 3.02Å; F200-L203 HydrophobicContact CD1-CD1 4.12Å; F200-L203 HydrophobicContact CE1-CD1 4.24Å; F200-L203 PolarHBondContact O-N 3.47Å; F200-T204 PolarHBondContact O-N 3.2Å; F200-T204 PolarHBondContact O-OG1 3.23Å; F200-L216 HydrophobicContact CD1-CD2 3.75Å; F200-L216 HydrophobicContact CE1-CD2 4.17Å; F200-M219 HydrophobicContact CB-CB 4.04Å; F200-M219 HydrophobicContact CD1-CB 3.49Å; F200-M219 VanDerWaalsContact CD1-CB 3.49Å; F200-M219 HydrophobicContact CD1-CG 4.08Å; F200-M219 HydrophobicContact CD2-CB 3.92Å; F200-M219 HydrophobicContact CE1-CB 3.87Å; F200-M219 HydrophobicContact CE1-CG 3.99Å; F200-M219 HydrophobicContact CE2-CB 4.28Å; F200-M219 HydrophobicContact CG-CB 3.52Å; F200-M219 HydrophobicContact CZ-CB 4.25Å; F200-M219 HydrophobicContact CZ-CG 4.35Å; F200-V220 HydrophobicContact CB-CG2 3.84Å
201	S	96.1	Very high	95.5	Very high	2 Å²	2	45.6 Å²	45.6	1%	0.014	25%	0.245	C	C	.	.	H	α-helix	trans	-64.4	-43.3	170	-171.7	0	0	0	0	110.7	E137 S197 Y199 L203 T204 S205 V220 I278	E137-S201 WeakPolarHBondContact OE1-CB 3.49Å; E137-S201 PolarHBondContact OE1-OG 3.28Å; E137-S201 PolarHBondContact OE2-OG 3.16Å; S197-S201 WeakPolarHBondContact O-CB 3.48Å; S197-S201 PolarHBondContact O-N 2.78Å; Y199-S201 PolarHBondContact O-N 3.01Å; S201-L203 PolarHBondContact O-N 2.87Å; S201-T204 VanDerWaalsContact O-CB 3.28Å; S201-T204 WeakPolarHBondContact O-CB 3.39Å; S201-T204 PolarHBondContact O-N 3.05Å; S201-T204 VanDerWaalsContact O-N 3.12Å; S201-S205 PolarHBondContact O-N 2.92Å; S201-V220 VanDerWaalsContact N-CG2 3.35Å; S201-I278 WeakPolarHBondContact O-CG2 3.41Å
202	L	96.6	Very high	95.7	Very high	74 Å²	74	49.2 Å²	49.2	39%	0.387	26%	0.257	S	S	.	.	H	α-helix	trans	-61.1	-47.5	175.8	-174.1	58	0	0	0	111.7	A198 Y199 T204 S205 F206 R279 I282	A198-L202 WeakPolarHBondContact O-CB 3.47Å; A198-L202 PolarHBondContact O-N 3.19Å; Y199-L202 WeakPolarHBondContact O-CB 3.29Å; Y199-L202 PolarHBondContact O-N 3.48Å; L202-T204 VanDerWaalsContact C-N 3.25Å; L202-T204 PolarHBondContact O-N 2.83Å; L202-S205 WeakPolarHBondContact O-CB 3.28Å; L202-S205 PolarHBondContact O-N 2.76Å; L202-S205 VanDerWaalsContact O-N 3.12Å; L202-S205 PolarHBondContact O-OG 3.36Å; L202-F206 HydrophobicContact CD1-CE2 4.11Å; L202-F206 HydrophobicContact CG-CE2 4.22Å; L202-F206 VanDerWaalsContact O-CD2 3.26Å; L202-F206 WeakPolarHBondContact O-CD2 3.35Å; L202-R279 HydrophobicContact CD1-CG 4.18Å; L202-I282 HydrophobicContact CB-CD1 3.77Å; L202-I282 HydrophobicContact CD1-CD1 4.06Å
203	L	97.3	Very high	95.8	Very high	55 Å²	55	47.6 Å²	47.6	29%	0.288	24%	0.24	S	C	.	.	H	α-helix	trans	-59.3	-35.4	175.5	-70.8	-179.6	0	0	0	112.5	Y199 F200 S201 S205 F206 A207 L216	Y199-L203 HydrophobicContact CD1-CD1 4.1Å; Y199-L203 HydrophobicContact CE1-CD1 3.5Å; Y199-L203 HydrophobicContact CE1-CG 4.39Å; Y199-L203 HydrophobicContact CE2-CD1 4.3Å; Y199-L203 HydrophobicContact CE2-CG 4.47Å; Y199-L203 WeakPolarHBondContact O-CG 3.36Å; Y199-L203 PolarHBondContact O-N 3.48Å; F200-L203 HydrophobicContact CD1-CD1 4.12Å; F200-L203 HydrophobicContact CE1-CD1 4.24Å; F200-L203 PolarHBondContact O-N 3.47Å; S201-L203 PolarHBondContact O-N 2.87Å; L203-S205 PolarHBondContact O-N 3.47Å; L203-F206 WeakPolarHBondContact O-CA 3.31Å; L203-F206 PolarHBondContact O-N 3.24Å; L203-A207 PolarHBondContact O-N 3.1Å; L203-L216 HydrophobicContact CB-CD1 4.15Å; L203-L216 HydrophobicContact CB-CD2 3.86Å; L203-L216 HydrophobicContact CD1-CD2 4.04Å
204	T	96.9	Very high	95.9	Very high	1 Å²	1	48.6 Å²	48.6	1%	0.006	24%	0.243	C	C	.	.	H	α-helix	trans	-57.6	-34.2	177	-58.6	0	0	0	0	111.5	F200 S201 L202 F206 A207 F213 L216 R217 I278	F200-T204 PolarHBondContact O-N 3.2Å; F200-T204 PolarHBondContact O-OG1 3.23Å; S201-T204 VanDerWaalsContact O-CB 3.28Å; S201-T204 WeakPolarHBondContact O-CB 3.39Å; S201-T204 PolarHBondContact O-N 3.05Å; S201-T204 VanDerWaalsContact O-N 3.12Å; L202-T204 VanDerWaalsContact C-N 3.25Å; L202-T204 PolarHBondContact O-N 2.83Å; T204-F206 PolarHBondContact O-N 3.5Å; T204-A207 WeakPolarHBondContact O-CB 3.25Å; T204-A207 PolarHBondContact O-N 3.02Å; T204-F213 HydrophobicContact CG2-CD2 3.49Å; T204-F213 VanDerWaalsContact CG2-CD2 3.49Å; T204-F213 HydrophobicContact CG2-CE2 3.32Å; T204-F213 HydrophobicContact CG2-CG 4.46Å; T204-F213 HydrophobicContact CG2-CZ 4.19Å; T204-L216 WeakPolarHBondContact OG1-CB 3.43Å; T204-R217 HydrophobicContact CG2-CG 3.95Å; T204-I278 HydrophobicContact CG2-CD1 4.09Å
205	S	96.2	Very high	96.2	Very high	0 Å²	0	53 Å²	53	0%	0	26%	0.263	C	S	.	.	T	Hydrogen-bonded Turn	trans	-67.8	-10.7	175.3	81.1	0	0	0	0	115.2	S201 L202 L203 R275 R279	S201-S205 PolarHBondContact O-N 2.92Å; L202-S205 WeakPolarHBondContact O-CB 3.28Å; L202-S205 PolarHBondContact O-N 2.76Å; L202-S205 VanDerWaalsContact O-N 3.12Å; L202-S205 PolarHBondContact O-OG 3.36Å; L203-S205 PolarHBondContact O-N 3.47Å; S205-R275 WeakPolarHBondContact CB-O 3.24Å; S205-R279 PolarHBondContact O-NH2 3.25Å; S205-R279 VanDerWaalsContact OG-CG 3.32Å; S205-R279 WeakPolarHBondContact OG-CG 3.49Å; S205-R279 PolarHBondContact OG-NE 3.28Å; S205-R279 VanDerWaalsContact OG-NE 3.15Å
206	F	96.3	Very high	96.3	Very high	123 Å²	123	50.6 Å²	50.6	54%	0.539	25%	0.248	S	C	.	.	T	Hydrogen-bonded Turn	trans	-111.8	7.3	177.1	-61.1	-78	0	0	0	112.6	L202 L203 T204 P208	L202-F206 HydrophobicContact CD1-CE2 4.11Å; L202-F206 HydrophobicContact CG-CE2 4.22Å; L202-F206 VanDerWaalsContact O-CD2 3.26Å; L202-F206 WeakPolarHBondContact O-CD2 3.35Å; L203-F206 WeakPolarHBondContact O-CA 3.31Å; L203-F206 PolarHBondContact O-N 3.24Å; T204-F206 PolarHBondContact O-N 3.5Å; F206-P208 VanDerWaalsContact O-CD 3.29Å; F206-P208 WeakPolarHBondContact O-CD 3.45Å; F206-P208 VanDerWaalsContact O-N 3.17Å
207	A	96.4	Very high	96.3	Very high	1 Å²	1	45 Å²	45	1%	0.008	23%	0.227	C	C	.	.			trans	-58.4	118.1	-179.6	0	0	0	0	0	111	W152 L203 T204 W212 F213 L216	W152-A207 HydrophobicContact CH2-CB 4.46Å; L203-A207 PolarHBondContact O-N 3.1Å; T204-A207 WeakPolarHBondContact O-CB 3.25Å; T204-A207 PolarHBondContact O-N 3.02Å; A207-W212 HydrophobicContact CB-CB 4.46Å; A207-F213 HydrophobicContact CB-CB 3.88Å; A207-F213 HydrophobicContact CB-CD2 4.01Å; A207-F213 HydrophobicContact CB-CG 4.46Å; A207-L216 HydrophobicContact CB-CD1 4.28Å
208	P	94.4	Very high	96.3	Very high	90 Å²	90	45.9 Å²	45.9	58%	0.584	23%	0.233	S	C	*	.			trans	-81.5	-25.3	-178.2	32.1	-34.9	0	0	0	112.2	F206 W212	F206-P208 VanDerWaalsContact O-CD 3.29Å; F206-P208 WeakPolarHBondContact O-CD 3.45Å; F206-P208 VanDerWaalsContact O-N 3.17Å; P208-W212 HydrophobicContact CG-CG 4.38Å
209	T	95.2	Very high	96.4	Very high	71 Å²	71	47.8 Å²	47.8	44%	0.436	24%	0.24	S	C	.	.	S	Bend	trans	-138.8	156.3	-178.2	68.1	0	0	0	0	111	G211 W212 F213	T209-G211 VanDerWaalsContact C-N 3.27Å; T209-G211 PolarHBondContact O-N 3.02Å; T209-W212 PolarHBondContact O-N 3.45Å; T209-W212 VanDerWaalsContact O-N 3.14Å; T209-F213 PolarHBondContact O-N 3.31Å
210	Y	95	Very high	96.4	Very high	37 Å²	37	41.5 Å²	41.5	15%	0.145	22%	0.216	C	C	.	.	H	α-helix	trans	-52	-39.5	176	169.6	-110.4	0	0	0	113.8	W152 L154 Q158 V162 F213 I214	W152-Y210 HydrophobicContact CE3-CD2 4.27Å; L154-Y210 HydrophobicContact CD1-CD2 3.63Å; L154-Y210 HydrophobicContact CD1-CE2 3.74Å; L154-Y210 HydrophobicContact CD2-CD1 4.26Å; L154-Y210 HydrophobicContact CD2-CD2 3.72Å; L154-Y210 HydrophobicContact CD2-CE2 4.07Å; L154-Y210 HydrophobicContact CD2-CG 3.83Å; L154-Y210 HydrophobicContact CG-CD2 4.35Å; Q158-Y210 VanDerWaalsContact C-OH 3.32Å; Q158-Y210 WeakPolarHBondContact CA-OH 3.45Å; Q158-Y210 HydrophobicContact CB-CE1 4.25Å; Q158-Y210 HydrophobicContact CB-CE2 4.19Å; Q158-Y210 VanDerWaalsContact CB-OH 3.3Å; Q158-Y210 WeakPolarHBondContact CB-OH 3.48Å; Q158-Y210 HydrophobicContact CG-CE1 4.34Å; Q158-Y210 PolarHBondContact O-OH 2.98Å; V162-Y210 HydrophobicContact CG2-CD2 4.44Å; V162-Y210 HydrophobicContact CG2-CE2 3.66Å; Y210-F213 WeakPolarHBondContact O-CB 3.32Å; Y210-F213 PolarHBondContact O-N 2.98Å; Y210-I214 HydrophobicContact CD1-CD1 3.99Å; Y210-I214 HydrophobicContact CD2-CD1 4.38Å; Y210-I214 HydrophobicContact CD2-CG1 4.39Å; Y210-I214 HydrophobicContact CE1-CD1 3.39Å; Y210-I214 HydrophobicContact CE1-CG1 4.36Å; Y210-I214 HydrophobicContact CE2-CD1 3.84Å; Y210-I214 HydrophobicContact CE2-CG1 3.92Å; Y210-I214 HydrophobicContact CG-CD1 4.44Å; Y210-I214 WeakPolarHBondContact O-CG1 3.26Å; Y210-I214 PolarHBondContact O-N 3.08Å; Y210-I214 WeakPolarHBondContact OH-CD1 3.19Å
211	G	96.1	Very high	96.3	Very high	45 Å²	45	40.2 Å²	40.2	46%	0.464	21%	0.21	S	C	.	.	H	α-helix	trans	-63.3	-42.4	177.4	0	0	0	0	0	113.5	T209 F213 F215	T209-G211 VanDerWaalsContact C-N 3.27Å; T209-G211 PolarHBondContact O-N 3.02Å; G211-F213 VanDerWaalsContact C-N 3.34Å; G211-F215 PolarHBondContact O-N 3.05Å
212	W	96.4	Very high	96.3	Very high	140 Å²	140	41.2 Å²	41.2	53%	0.53	22%	0.217	S	C	.	.	H	α-helix	trans	-64.2	-39.9	171.8	-84.4	110.9	0	0	0	111.7	A207 P208 T209 F215 L216	A207-W212 HydrophobicContact CB-CB 4.46Å; P208-W212 HydrophobicContact CG-CG 4.38Å; T209-W212 PolarHBondContact O-N 3.45Å; T209-W212 VanDerWaalsContact O-N 3.14Å; W212-F215 HydrophobicContact CE3-CD1 4.09Å; W212-F215 HydrophobicContact CZ3-CD1 4.01Å; W212-F215 HydrophobicContact CZ3-CE1 4.22Å; W212-F215 PolarHBondContact O-N 3.11Å; W212-L216 WeakPolarHBondContact O-CB 3.49Å; W212-L216 WeakPolarHBondContact O-CD1 3.37Å; W212-L216 WeakPolarHBondContact O-CG 3.26Å; W212-L216 PolarHBondContact O-N 3.22Å
213	F	96.1	Very high	96.2	Very high	1 Å²	1	37.7 Å²	37.7	0%	0.004	20%	0.199	C	C	.	.	H	α-helix	trans	-61.1	-46.4	178.6	-173.2	-98.6	0	0	0	112.3	V144 I148 W152 V162 T204 A207 T209 Y210 G211 R217 W274 I278	V144-F213 HydrophobicContact CG1-CZ 3.97Å; I148-F213 HydrophobicContact CD1-CD1 4.36Å; I148-F213 HydrophobicContact CD1-CE1 3.57Å; I148-F213 HydrophobicContact CD1-CZ 4.16Å; I148-F213 HydrophobicContact CG2-CE1 4.12Å; I148-F213 HydrophobicContact CG2-CE2 4.28Å; I148-F213 HydrophobicContact CG2-CZ 3.86Å; W152-F213 HydrophobicContact CH2-CB 3.57Å; W152-F213 HydrophobicContact CH2-CD1 4.45Å; W152-F213 AromaticContact CH2-CD2 3.77Å; W152-F213 HydrophobicContact CH2-CD2 3.77Å; W152-F213 AromaticContact CH2-CG 3.7Å; W152-F213 HydrophobicContact CH2-CG 3.7Å; W152-F213 HydrophobicContact CZ3-CB 3.75Å; W152-F213 AromaticContact CZ3-CD1 3.94Å; W152-F213 HydrophobicContact CZ3-CD1 3.94Å; W152-F213 HydrophobicContact CZ3-CD2 4.02Å; W152-F213 AromaticContact CZ3-CG 3.65Å; W152-F213 HydrophobicContact CZ3-CG 3.65Å; V162-F213 HydrophobicContact CG1-CD1 4Å; V162-F213 HydrophobicContact CG1-CE1 3.6Å; V162-F213 HydrophobicContact CG2-CD1 4.14Å; V162-F213 HydrophobicContact CG2-CE1 4.22Å; T204-F213 HydrophobicContact CG2-CD2 3.49Å; T204-F213 VanDerWaalsContact CG2-CD2 3.49Å; T204-F213 HydrophobicContact CG2-CE2 3.32Å; T204-F213 HydrophobicContact CG2-CG 4.46Å; T204-F213 HydrophobicContact CG2-CZ 4.19Å; A207-F213 HydrophobicContact CB-CB 3.88Å; A207-F213 HydrophobicContact CB-CD2 4.01Å; A207-F213 HydrophobicContact CB-CG 4.46Å; T209-F213 PolarHBondContact O-N 3.31Å; Y210-F213 WeakPolarHBondContact O-CB 3.32Å; Y210-F213 PolarHBondContact O-N 2.98Å; G211-F213 VanDerWaalsContact C-N 3.34Å; F213-R217 HydrophobicContact CD1-CG 4.44Å; F213-R217 HydrophobicContact CE1-CG 4.25Å; F213-R217 HydrophobicContact CZ-CG 4.36Å; F213-R217 VanDerWaalsContact O-CB 3.3Å; F213-R217 WeakPolarHBondContact O-CB 3.36Å; F213-R217 VanDerWaalsContact O-CG 3.28Å; F213-R217 WeakPolarHBondContact O-CG 3.47Å; F213-R217 PolarHBondContact O-N 3.17Å; F213-W274 HydrophobicContact CD2-CH2 4.09Å; F213-W274 HydrophobicContact CD2-CZ3 4.21Å; F213-W274 HydrophobicContact CE2-CE3 4.48Å; F213-W274 AromaticContact CE2-CH2 3.92Å; F213-W274 HydrophobicContact CE2-CH2 3.92Å; F213-W274 AromaticContact CE2-CZ3 3.64Å; F213-W274 HydrophobicContact CE2-CZ3 3.64Å; F213-I278 HydrophobicContact CE2-CD1 4.47Å
214	I	96.6	Very high	96	Very high	27 Å²	27	35.2 Å²	35.2	14%	0.138	19%	0.186	C	C	.	.	H	α-helix	trans	-57.5	-52.3	173.2	-64	160.1	0	0	0	110.7	L161 V162 M165 Y210 L216 R217 S218	L161-I214 HydrophobicContact CD2-CD1 4.21Å; V162-I214 HydrophobicContact CG2-CG1 4.07Å; M165-I214 HydrophobicContact CB-CG2 3.84Å; M165-I214 HydrophobicContact CG-CG2 3.76Å; Y210-I214 HydrophobicContact CD1-CD1 3.99Å; Y210-I214 HydrophobicContact CD2-CD1 4.38Å; Y210-I214 HydrophobicContact CD2-CG1 4.39Å; Y210-I214 HydrophobicContact CE1-CD1 3.39Å; Y210-I214 HydrophobicContact CE1-CG1 4.36Å; Y210-I214 HydrophobicContact CE2-CD1 3.84Å; Y210-I214 HydrophobicContact CE2-CG1 3.92Å; Y210-I214 HydrophobicContact CG-CD1 4.44Å; Y210-I214 WeakPolarHBondContact O-CG1 3.26Å; Y210-I214 PolarHBondContact O-N 3.08Å; Y210-I214 WeakPolarHBondContact OH-CD1 3.19Å; I214-L216 PolarHBondContact O-N 3.06Å; I214-R217 PolarHBondContact O-N 3.46Å; I214-R217 VanDerWaalsContact O-N 3.14Å; I214-S218 PolarHBondContact O-N 3.47Å; I214-S218 PolarHBondContact O-OG 3.17Å
215	F	97.3	Very high	95.7	Very high	95 Å²	95	35.1 Å²	35.1	42%	0.417	19%	0.186	S	C	.	.	H	α-helix	trans	-58.3	-47.4	-175.7	172.2	-99	0	0	0	112	G211 W212 R217 S218 M219	G211-F215 PolarHBondContact O-N 3.05Å; W212-F215 HydrophobicContact CE3-CD1 4.09Å; W212-F215 HydrophobicContact CZ3-CD1 4.01Å; W212-F215 HydrophobicContact CZ3-CE1 4.22Å; W212-F215 PolarHBondContact O-N 3.11Å; F215-R217 VanDerWaalsContact C-N 3.31Å; F215-R217 PolarHBondContact O-N 3.32Å; F215-S218 WeakPolarHBondContact O-CB 3.41Å; F215-S218 PolarHBondContact O-N 2.96Å; F215-M219 HydrophobicContact CD2-CE 4.29Å; F215-M219 HydrophobicContact CE1-CG 4.31Å; F215-M219 HydrophobicContact CE2-CE 3.51Å; F215-M219 HydrophobicContact CZ-CE 3.77Å; F215-M219 HydrophobicContact CZ-CG 4.19Å; F215-M219 WeakPolarHBondContact O-CG 3.29Å; F215-M219 PolarHBondContact O-N 2.84Å; F215-M219 VanDerWaalsContact O-N 3.11Å
216	L	97.4	Very high	95.5	Very high	12 Å²	12	35.3 Å²	35.3	6%	0.063	19%	0.187	C	C	.	.	H	α-helix	trans	-64.6	-37.3	178.4	-64.4	167.9	0	0	0	111.2	F200 L203 T204 A207 W212 I214 M219 V220	F200-L216 HydrophobicContact CD1-CD2 3.75Å; F200-L216 HydrophobicContact CE1-CD2 4.17Å; L203-L216 HydrophobicContact CB-CD1 4.15Å; L203-L216 HydrophobicContact CB-CD2 3.86Å; L203-L216 HydrophobicContact CD1-CD2 4.04Å; T204-L216 WeakPolarHBondContact OG1-CB 3.43Å; A207-L216 HydrophobicContact CB-CD1 4.28Å; W212-L216 WeakPolarHBondContact O-CB 3.49Å; W212-L216 WeakPolarHBondContact O-CD1 3.37Å; W212-L216 WeakPolarHBondContact O-CG 3.26Å; W212-L216 PolarHBondContact O-N 3.22Å; I214-L216 PolarHBondContact O-N 3.06Å; L216-M219 PolarHBondContact O-N 3.46Å; L216-V220 PolarHBondContact O-N 3.38Å
217	R	95.9	Very high	95.2	Very high	1 Å²	1	29.8 Å²	29.8	0%	0.004	16%	0.164	C	C	.	.	H	α-helix	trans	-68.3	-37.3	174.9	-76.3	-61.9	-122	153.4	13.6	113.6	E137 L141 V162 V166 T204 F213 I214 F215 M219 V220 G221	E137-R217 PolarHBondContact O-NH1 2.95Å; E137-R217 VanDerWaalsContact O-NH1 3.13Å; E137-R217 IonicContact OE2-NH1 3.14Å; E137-R217 PolarHBondContact OE2-NH1 2.98Å; L141-R217 VanDerWaalsContact CD2-NH2 3.33Å; L141-R217 VanDerWaalsContact CG-NH2 3.33Å; V162-R217 HydrophobicContact CG1-CB 4.4Å; V162-R217 HydrophobicContact CG1-CG 4.3Å; V166-R217 HydrophobicContact CG2-CB 3.8Å; T204-R217 HydrophobicContact CG2-CG 3.95Å; F213-R217 HydrophobicContact CD1-CG 4.44Å; F213-R217 HydrophobicContact CE1-CG 4.25Å; F213-R217 HydrophobicContact CZ-CG 4.36Å; F213-R217 VanDerWaalsContact O-CB 3.3Å; F213-R217 WeakPolarHBondContact O-CB 3.36Å; F213-R217 VanDerWaalsContact O-CG 3.28Å; F213-R217 WeakPolarHBondContact O-CG 3.47Å; F213-R217 PolarHBondContact O-N 3.17Å; I214-R217 PolarHBondContact O-N 3.46Å; I214-R217 VanDerWaalsContact O-N 3.14Å; F215-R217 VanDerWaalsContact C-N 3.31Å; F215-R217 PolarHBondContact O-N 3.32Å; R217-M219 VanDerWaalsContact C-N 3.27Å; R217-M219 PolarHBondContact O-N 3.11Å; R217-V220 WeakPolarHBondContact O-CB 3.42Å; R217-V220 PolarHBondContact O-N 2.99Å; R217-G221 PolarHBondContact O-N 3.18Å
218	S	96.6	Very high	94.7	Very high	22 Å²	22	30.9 Å²	30.9	15%	0.154	17%	0.171	C	C	.	.	H	α-helix	trans	-58.3	-40.7	168.5	-59.8	0	0	0	0	111.7	M165 I214 F215 G221 C222	M165-S218 PolarHBondContact O-OG 3.44Å; I214-S218 PolarHBondContact O-N 3.47Å; I214-S218 PolarHBondContact O-OG 3.17Å; F215-S218 WeakPolarHBondContact O-CB 3.41Å; F215-S218 PolarHBondContact O-N 2.96Å; S218-G221 WeakPolarHBondContact O-CA 3.22Å; S218-G221 PolarHBondContact O-N 2.93Å; S218-C222 PolarHBondContact O-N 2.93Å; S218-C222 VanDerWaalsContact O-N 3.09Å
219	M	97.6	Very high	94.3	Very high	47 Å²	47	27.9 Å²	27.9	23%	0.232	15%	0.149	C	C	.	.	H	α-helix	trans	-69.9	-34.1	177.7	-65.6	-59.7	159.1	0	0	112.9	W196 F200 F215 L216 R217 G221 C222 G223	W196-M219 HydrophobicContact CZ2-SD 4.03Å; W196-M219 PolarHBondContact NE1-O 3.07Å; F200-M219 HydrophobicContact CB-CB 4.04Å; F200-M219 HydrophobicContact CD1-CB 3.49Å; F200-M219 VanDerWaalsContact CD1-CB 3.49Å; F200-M219 HydrophobicContact CD1-CG 4.08Å; F200-M219 HydrophobicContact CD2-CB 3.92Å; F200-M219 HydrophobicContact CE1-CB 3.87Å; F200-M219 HydrophobicContact CE1-CG 3.99Å; F200-M219 HydrophobicContact CE2-CB 4.28Å; F200-M219 HydrophobicContact CG-CB 3.52Å; F200-M219 HydrophobicContact CZ-CB 4.25Å; F200-M219 HydrophobicContact CZ-CG 4.35Å; F215-M219 HydrophobicContact CD2-CE 4.29Å; F215-M219 HydrophobicContact CE1-CG 4.31Å; F215-M219 HydrophobicContact CE2-CE 3.51Å; F215-M219 HydrophobicContact CZ-CE 3.77Å; F215-M219 HydrophobicContact CZ-CG 4.19Å; F215-M219 WeakPolarHBondContact O-CG 3.29Å; F215-M219 PolarHBondContact O-N 2.84Å; F215-M219 VanDerWaalsContact O-N 3.11Å; L216-M219 PolarHBondContact O-N 3.46Å; R217-M219 VanDerWaalsContact C-N 3.27Å; R217-M219 PolarHBondContact O-N 3.11Å; M219-G221 VanDerWaalsContact C-N 3.35Å; M219-C222 WeakPolarHBondContact O-CB 3.46Å; M219-C222 PolarHBondContact O-N 2.9Å; M219-G223 PolarHBondContact O-N 3.22Å; M219-G223 VanDerWaalsContact O-N 3.1Å
220	V	96.9	Very high	93.9	Very high	1 Å²	1	24.6 Å²	24.6	1%	0.006	13%	0.13	C	C	.	.	H	α-helix	trans	-58.6	-47.2	166.8	171.1	0	0	0	0	110.4	E137 F200 S201 L216 R217 C222 G223 V224	E137-V220 HydrophobicContact CB-CG1 4.32Å; E137-V220 HydrophobicContact CG-CG1 4.36Å; E137-V220 WeakPolarHBondContact OE2-CG1 3.48Å; F200-V220 HydrophobicContact CB-CG2 3.84Å; S201-V220 VanDerWaalsContact N-CG2 3.35Å; L216-V220 PolarHBondContact O-N 3.38Å; R217-V220 WeakPolarHBondContact O-CB 3.42Å; R217-V220 PolarHBondContact O-N 2.99Å; V220-C222 PolarHBondContact O-N 3.5Å; V220-G223 WeakPolarHBondContact O-CA 3.39Å; V220-G223 PolarHBondContact O-N 3.4Å; V220-V224 HydrophobicContact CG1-CG2 4.16Å; V220-V224 WeakPolarHBondContact O-CG2 3.41Å; V220-V224 PolarHBondContact O-N 3.45Å
221	G	95.4	Very high	93.2	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-52.8	-40.2	174.6	0	0	0	0	0	113.3	V166 F170 R217 S218 M219 V224 A225	V166-G221 WeakPolarHBondContact O-CA 3.47Å; F170-G221 WeakPolarHBondContact CA-O 3.47Å; R217-G221 PolarHBondContact O-N 3.18Å; S218-G221 WeakPolarHBondContact O-CA 3.22Å; S218-G221 PolarHBondContact O-N 2.93Å; M219-G221 VanDerWaalsContact C-N 3.35Å; G221-V224 PolarHBondContact O-N 3.14Å; G221-A225 PolarHBondContact O-N 3Å
222	C	95.3	Very high	92.5	Very high	22 Å²	22	25.6 Å²	25.6	15%	0.149	13%	0.126	C	C	.	.	H	α-helix	trans	-65.4	-38.7	173.3	-77.2	0	0	0	0	114.2	G169 C173 S218 M219 V220 A225 G226	G169-C222 PolarHBondContact O-SG 3.2Å; C173-C222 HydrophobicContact CB-CB 3.5Å; C173-C222 VanDerWaalsContact CB-CB 3.5Å; C173-C222 WeakPolarHBondContact CB-SG 3.07Å; C173-C222 WeakPolarHBondContact SG-CB 3.5Å; C173-C222 CovalentContact SG-SG 2.04Å; C173-C222 PolarHBondContact SG-SG 3.11Å; S218-C222 PolarHBondContact O-N 2.93Å; S218-C222 VanDerWaalsContact O-N 3.09Å; M219-C222 WeakPolarHBondContact O-CB 3.46Å; M219-C222 PolarHBondContact O-N 2.9Å; V220-C222 PolarHBondContact O-N 3.5Å; C222-A225 WeakPolarHBondContact O-CB 3.38Å; C222-A225 PolarHBondContact O-N 3.17Å; C222-G226 PolarHBondContact O-N 2.96Å
223	G	94.8	Very high	92	Very high	1 Å²	1	19 Å²	19	1%	0.01	10%	0.101	C	C	.	.	H	α-helix	trans	-64.8	-46.5	173.9	0	0	0	0	0	112	G193 M219 V220 A225 G226 V227	G193-G223 WeakPolarHBondContact CA-O 3.45Å; M219-G223 PolarHBondContact O-N 3.22Å; M219-G223 VanDerWaalsContact O-N 3.1Å; V220-G223 WeakPolarHBondContact O-CA 3.39Å; V220-G223 PolarHBondContact O-N 3.4Å; G223-A225 PolarHBondContact O-N 3.31Å; G223-G226 WeakPolarHBondContact O-CA 3.36Å; G223-G226 PolarHBondContact O-N 3.4Å; G223-V227 PolarHBondContact O-N 2.86Å
224	V	93.3	Very high	91.5	Very high	2 Å²	2	19.6 Å²	19.6	1%	0.012	10%	0.104	C	C	.	.	H	α-helix	trans	-57.9	-36.3	174.9	177.9	0	0	0	0	111.6	E134 E137 I138 F170 V220 G221 G226 V227 S228	E134-V224 HydrophobicContact CG-CG1 3.94Å; E137-V224 HydrophobicContact CB-CG2 4.1Å; I138-V224 HydrophobicContact CD1-CG1 4Å; I138-V224 HydrophobicContact CG1-CG1 4.25Å; F170-V224 HydrophobicContact CD1-CB 4.49Å; F170-V224 HydrophobicContact CD1-CG1 3.9Å; F170-V224 HydrophobicContact CE1-CB 4.41Å; F170-V224 HydrophobicContact CE1-CG1 3.44Å; F170-V224 VanDerWaalsContact CE1-CG1 3.44Å; F170-V224 HydrophobicContact CZ-CG1 4.06Å; V220-V224 HydrophobicContact CG1-CG2 4.16Å; V220-V224 WeakPolarHBondContact O-CG2 3.41Å; V220-V224 PolarHBondContact O-N 3.45Å; G221-V224 PolarHBondContact O-N 3.14Å; V224-G226 VanDerWaalsContact C-N 3.32Å; V224-G226 PolarHBondContact O-N 3.22Å; V224-V227 WeakPolarHBondContact O-CB 3.13Å; V224-V227 PolarHBondContact O-N 3.22Å; V224-V227 VanDerWaalsContact O-N 3.15Å; V224-S228 PolarHBondContact O-N 3Å
225	A	91.6	Very high	90.7	Very high	0 Å²	0	19.8 Å²	19.8	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-59.2	-40.8	173.7	0	0	0	0	0	113	F170 C173 G221 C222 G223 S228	F170-A225 HydrophobicContact CD2-CB 3.78Å; F170-A225 HydrophobicContact CE2-CB 4.1Å; F170-A225 HydrophobicContact CG-CB 4.41Å; F170-A225 WeakPolarHBondContact O-CB 3.28Å; C173-A225 HydrophobicContact CB-CB 4.1Å; G221-A225 PolarHBondContact O-N 3Å; C222-A225 WeakPolarHBondContact O-CB 3.38Å; C222-A225 PolarHBondContact O-N 3.17Å; G223-A225 PolarHBondContact O-N 3.31Å; A225-S228 PolarHBondContact O-OG 2.93Å
226	G	91	Very high	90.1	Very high	4 Å²	4	16.5 Å²	16.5	4%	0.041	9%	0.092	C	C	.	.	H	α-helix	trans	-67.3	-41.9	172.3	0	0	0	0	0	112.5	C222 G223 V224 S228 Q229	C222-G226 PolarHBondContact O-N 2.96Å; G223-G226 WeakPolarHBondContact O-CA 3.36Å; G223-G226 PolarHBondContact O-N 3.4Å; V224-G226 VanDerWaalsContact C-N 3.32Å; V224-G226 PolarHBondContact O-N 3.22Å; G226-S228 VanDerWaalsContact C-N 3.31Å; G226-S228 PolarHBondContact O-N 3.25Å; G226-Q229 WeakPolarHBondContact O-CB 3.44Å; G226-Q229 PolarHBondContact O-N 3.09Å
227	V	90.6	Very high	89.6	Confident	6 Å²	6	16.1 Å²	16.1	4%	0.036	9%	0.09	C	C	.	.	H	α-helix	trans	-55.7	-43.7	174.8	168.6	0	0	0	0	112	E134 Y194 G223 V224 Q229 G230	E134-V227 HydrophobicContact CB-CG1 4.11Å; Y194-V227 HydrophobicContact CD1-CG2 4.37Å; Y194-V227 HydrophobicContact CD2-CG2 3.81Å; Y194-V227 HydrophobicContact CE1-CG2 4.23Å; Y194-V227 HydrophobicContact CE2-CB 4.08Å; Y194-V227 HydrophobicContact CE2-CG1 3.66Å; Y194-V227 HydrophobicContact CE2-CG2 3.62Å; Y194-V227 HydrophobicContact CG-CG2 4.11Å; Y194-V227 WeakPolarHBondContact OH-CG1 3.23Å; G223-V227 PolarHBondContact O-N 2.86Å; V224-V227 WeakPolarHBondContact O-CB 3.13Å; V224-V227 PolarHBondContact O-N 3.22Å; V224-V227 VanDerWaalsContact O-N 3.15Å; V227-Q229 PolarHBondContact O-N 3.2Å; V227-Q229 VanDerWaalsContact O-N 3.09Å; V227-G230 PolarHBondContact O-N 3.49Å
228	S	85.4	Confident	89.1	Confident	24 Å²	24	16.4 Å²	16.4	17%	0.168	9%	0.091	C	C	.	.	H	α-helix	trans	-62.1	-21.1	-175.7	74.8	0	0	0	0	114.3	V224 A225 G226 G230 F231	V224-S228 PolarHBondContact O-N 3Å; A225-S228 PolarHBondContact O-OG 2.93Å; G226-S228 VanDerWaalsContact C-N 3.31Å; G226-S228 PolarHBondContact O-N 3.25Å; S228-G230 PolarHBondContact O-N 3.3Å; S228-G230 VanDerWaalsContact O-N 3.12Å; S228-F231 PolarHBondContact O-N 3Å; S228-F231 VanDerWaalsContact O-N 3.17Å
229	Q	86.1	Confident	88.4	Confident	27 Å²	27	15.6 Å²	15.6	13%	0.126	9%	0.085	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62	-17.2	171.2	-59.6	-59.9	-52.1	0	0	112.8	A177 A181 V189 V190 G226 V227 F231 V232 L233	A177-Q229 HydrophobicContact CB-CG 4.48Å; A181-Q229 HydrophobicContact CB-CG 4.43Å; V189-Q229 HydrophobicContact CG1-CG 4.15Å; V190-Q229 HydrophobicContact CG2-CB 3.8Å; G226-Q229 WeakPolarHBondContact O-CB 3.44Å; G226-Q229 PolarHBondContact O-N 3.09Å; V227-Q229 PolarHBondContact O-N 3.2Å; V227-Q229 VanDerWaalsContact O-N 3.09Å; Q229-F231 PolarHBondContact O-N 3.25Å; Q229-V232 PolarHBondContact O-N 3.1Å; Q229-V232 VanDerWaalsContact O-N 3.14Å; Q229-L233 PolarHBondContact O-N 2.9Å
230	G	85.8	Confident	87.3	Confident	3 Å²	3	15.4 Å²	15.4	3%	0.031	9%	0.092	C	C	.	.	H	α-helix	trans	-61.9	-24.2	174.7	0	0	0	0	0	113.4	V190 V227 S228 K234	V190-G230 VanDerWaalsContact CG2-N 3.27Å; V227-G230 PolarHBondContact O-N 3.49Å; S228-G230 PolarHBondContact O-N 3.3Å; S228-G230 VanDerWaalsContact O-N 3.12Å; G230-K234 WeakPolarHBondContact O-CB 3.37Å; G230-K234 WeakPolarHBondContact O-CE 3.49Å; G230-K234 WeakPolarHBondContact O-CG 3.11Å; G230-K234 PolarHBondContact O-N 3.15Å
231	F	81.6	Confident	86.3	Confident	61 Å²	61	23.1 Å²	23.1	27%	0.268	13%	0.125	S	C	.	.	H	α-helix	trans	-62.1	-47.6	171.4	-177.2	-93.9	0	0	0	111.7	S228 Q229 K234 T235 L247 M502	S228-F231 PolarHBondContact O-N 3Å; S228-F231 VanDerWaalsContact O-N 3.17Å; Q229-F231 PolarHBondContact O-N 3.25Å; F231-K234 WeakPolarHBondContact O-CB 3.48Å; F231-K234 PolarHBondContact O-N 2.99Å; F231-T235 HydrophobicContact CE1-CG2 4.33Å; F231-T235 PolarHBondContact O-N 2.95Å; F231-L247 HydrophobicContact CE2-CD2 3.83Å; F231-L247 HydrophobicContact CZ-CD1 4.33Å; F231-L247 HydrophobicContact CZ-CD2 4.07Å; F231-M502 HydrophobicContact CE1-CE 4.44Å; F231-M502 HydrophobicContact CE1-SD 4.35Å
232	V	80.4	Confident	85.5	Confident	42 Å²	42	27.4 Å²	27.4	26%	0.255	14%	0.142	S	C	.	.	H	α-helix	trans	-66.2	-45.4	178.7	-170.2	0	0	0	0	110.1	Q229 K234 T235 E236	Q229-V232 PolarHBondContact O-N 3.1Å; Q229-V232 VanDerWaalsContact O-N 3.14Å; V232-K234 VanDerWaalsContact C-N 3.31Å; V232-K234 PolarHBondContact O-N 3.15Å; V232-T235 PolarHBondContact O-N 2.88Å; V232-T235 PolarHBondContact O-OG1 3.12Å; V232-E236 PolarHBondContact O-N 3.09Å; V232-E236 VanDerWaalsContact O-N 3.13Å
233	L	85.9	Confident	84.5	Confident	0 Å²	0	28.9 Å²	28.9	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-55.2	-43.5	176.7	-175.5	61.3	0	0	0	112.3	M127 R186 W187 Q229 T235 E236 F237	M127-L233 HydrophobicContact SD-CD2 4.14Å; R186-L233 HydrophobicContact CB-CB 4.41Å; R186-L233 HydrophobicContact CB-CD1 4.11Å; W187-L233 HydrophobicContact CB-CD2 4.25Å; Q229-L233 PolarHBondContact O-N 2.9Å; L233-T235 PolarHBondContact O-N 3.44Å; L233-E236 PolarHBondContact O-N 3.34Å; L233-F237 HydrophobicContact CD1-CD2 4.33Å; L233-F237 HydrophobicContact CD1-CE2 3.62Å; L233-F237 HydrophobicContact CD1-CZ 4.42Å; L233-F237 HydrophobicContact CG-CD2 4.5Å; L233-F237 HydrophobicContact CG-CE2 4.03Å; L233-F237 VanDerWaalsContact O-CD2 3.28Å; L233-F237 WeakPolarHBondContact O-CD2 3.31Å
234	K	85.6	Confident	83.2	Confident	15 Å²	15	32.4 Å²	32.4	7%	0.065	17%	0.173	C	C	.	.	H	α-helix	trans	-55.5	-47.2	172.5	-81.7	174.4	-97.2	-165.8	0	112	M127 N131 G230 F231 V232 E236 F237 I238	M127-K234 HydrophobicContact CB-CD 3.41Å; M127-K234 VanDerWaalsContact CB-CD 3.41Å; M127-K234 HydrophobicContact CB-CG 3.38Å; M127-K234 HydrophobicContact CG-CD 4.37Å; M127-K234 HydrophobicContact CG-CG 3.81Å; M127-K234 WeakPolarHBondContact O-CE 3.48Å; M127-K234 PolarHBondContact O-NZ 3.48Å; M127-K234 HydrophobicContact SD-CG 4.15Å; N131-K234 PolarHBondContact OD1-NZ 3.22Å; G230-K234 WeakPolarHBondContact O-CB 3.37Å; G230-K234 WeakPolarHBondContact O-CE 3.49Å; G230-K234 WeakPolarHBondContact O-CG 3.11Å; G230-K234 PolarHBondContact O-N 3.15Å; F231-K234 WeakPolarHBondContact O-CB 3.48Å; F231-K234 PolarHBondContact O-N 2.99Å; V232-K234 VanDerWaalsContact C-N 3.31Å; V232-K234 PolarHBondContact O-N 3.15Å; K234-E236 VanDerWaalsContact C-N 3.32Å; K234-E236 PolarHBondContact O-N 3.22Å; K234-F237 PolarHBondContact O-N 3.41Å; K234-I238 HydrophobicContact CB-CD1 4.48Å; K234-I238 WeakPolarHBondContact O-CD1 3.47Å; K234-I238 VanDerWaalsContact O-CG1 3.28Å; K234-I238 WeakPolarHBondContact O-CG1 3.46Å; K234-I238 PolarHBondContact O-N 3.18Å
235	T	80.8	Confident	82.2	Confident	31 Å²	31	40.9 Å²	40.9	19%	0.19	21%	0.206	C	C	.	.	H	α-helix	trans	-67.1	-28.8	-177.6	62.3	0	0	0	0	114.1	F231 V232 L233 R243 L247	F231-T235 HydrophobicContact CE1-CG2 4.33Å; F231-T235 PolarHBondContact O-N 2.95Å; V232-T235 PolarHBondContact O-N 2.88Å; V232-T235 PolarHBondContact O-OG1 3.12Å; L233-T235 PolarHBondContact O-N 3.44Å; T235-R243 PolarHBondContact O-NE 3.42Å; T235-R243 VanDerWaalsContact O-NE 3.08Å; T235-R243 PolarHBondContact O-NH2 3.49Å; T235-R243 VanDerWaalsContact O-NH2 3.1Å; T235-L247 HydrophobicContact CG2-CD1 4.1Å; T235-L247 HydrophobicContact CG2-CD2 3.94Å
236	E	84.8	Confident	81.5	Confident	26 Å²	26	41.8 Å²	41.8	12%	0.121	21%	0.211	C	C	.	.	H	α-helix	trans	-70.5	-29.6	-179.3	-70.3	-177.5	-163	0	0	113.2	R186 V232 L233 K234 S298	R186-E236 WeakPolarHBondContact CD-OE1 3.41Å; R186-E236 IonicContact CZ-OE1 3.42Å; R186-E236 IonicContact NE-OE1 3.32Å; R186-E236 PolarHBondContact NE-OE1 3.39Å; R186-E236 IonicContact NH2-OE1 2.8Å; V232-E236 PolarHBondContact O-N 3.09Å; V232-E236 VanDerWaalsContact O-N 3.13Å; L233-E236 PolarHBondContact O-N 3.34Å; K234-E236 VanDerWaalsContact C-N 3.32Å; K234-E236 PolarHBondContact O-N 3.22Å; E236-S298 WeakPolarHBondContact OE2-CB 3.14Å; E236-S298 PolarHBondContact OE2-OG 3.03Å
237	F	86	Confident	80.6	Confident	4 Å²	4	44.2 Å²	44.2	2%	0.018	22%	0.223	C	C	.	.	H	α-helix	trans	-86.7	-34.6	175.3	-69.9	-68.9	0	0	0	113.8	V111 F119 H120 L123 L233 K234 I295 P296 T314 I318	V111-F237 WeakPolarHBondContact CG1-O 3.28Å; F119-F237 HydrophobicContact CE1-CB 4.36Å; F119-F237 AromaticContact CE1-CD1 3.87Å; F119-F237 HydrophobicContact CE1-CD1 3.87Å; F119-F237 HydrophobicContact CE1-CE1 4.37Å; F119-F237 HydrophobicContact CE1-CG 4.14Å; F119-F237 HydrophobicContact CZ-CD1 4.16Å; F119-F237 HydrophobicContact CZ-CE1 4.22Å; H120-F237 PolarHBondContact NE2-O 3.45Å; H120-F237 VanDerWaalsContact NE2-O 3.15Å; L123-F237 HydrophobicContact CD1-CD2 4.09Å; L123-F237 HydrophobicContact CD1-CE2 4.44Å; L123-F237 HydrophobicContact CD2-CB 3.42Å; L123-F237 VanDerWaalsContact CD2-CB 3.42Å; L123-F237 HydrophobicContact CD2-CD2 3.78Å; L123-F237 HydrophobicContact CD2-CG 3.86Å; L233-F237 HydrophobicContact CD1-CD2 4.33Å; L233-F237 HydrophobicContact CD1-CE2 3.62Å; L233-F237 HydrophobicContact CD1-CZ 4.42Å; L233-F237 HydrophobicContact CG-CD2 4.5Å; L233-F237 HydrophobicContact CG-CE2 4.03Å; L233-F237 VanDerWaalsContact O-CD2 3.28Å; L233-F237 WeakPolarHBondContact O-CD2 3.31Å; K234-F237 PolarHBondContact O-N 3.41Å; F237-I295 HydrophobicContact CE2-CG2 4.43Å; F237-P296 HydrophobicContact CE1-CG 4.2Å; F237-P296 HydrophobicContact CZ-CG 4.1Å; F237-P296 WeakPolarHBondContact CZ-O 3.43Å; F237-T314 HydrophobicContact CE1-CG2 4.31Å; F237-I318 HydrophobicContact CD1-CD1 3.8Å; F237-I318 HydrophobicContact CE1-CD1 3.91Å
238	I	85.1	Confident	79.8	Confident	6 Å²	6	45.1 Å²	45.1	3%	0.031	23%	0.229	C	C	.	.	S	Bend	trans	-74.5	129	-173.5	-65	165.6	0	0	0	110.3	K234 R243 L246	K234-I238 HydrophobicContact CB-CD1 4.48Å; K234-I238 WeakPolarHBondContact O-CD1 3.47Å; K234-I238 VanDerWaalsContact O-CG1 3.28Å; K234-I238 WeakPolarHBondContact O-CG1 3.46Å; K234-I238 PolarHBondContact O-N 3.18Å; I238-R243 HydrophobicContact CB-CG 4.13Å; I238-R243 HydrophobicContact CG2-CB 4.47Å; I238-R243 HydrophobicContact CG2-CG 3.68Å; I238-R243 VanDerWaalsContact O-CZ 3.26Å; I238-R243 PolarHBondContact O-NE 2.9Å; I238-R243 PolarHBondContact O-NH2 3.42Å; I238-L246 HydrophobicContact CD1-CB 4.36Å; I238-L246 HydrophobicContact CD1-CD1 4.17Å; I238-L246 HydrophobicContact CG1-CD1 4.36Å; I238-L246 HydrophobicContact CG2-CD1 3.66Å
239	P	82.6	Confident	79.5	Confident	5 Å²	5	47.8 Å²	47.8	3%	0.032	24%	0.241	C	C	.	.			trans	-62.6	144.9	174.9	-19	29.6	0	0	0	112.5	V111 K241 Y242 R243	V111-P239 HydrophobicContact CG1-CB 4.16Å; V111-P239 HydrophobicContact CG1-CG 3.84Å; P239-K241 VanDerWaalsContact C-N 3.3Å; P239-K241 PolarHBondContact O-N 3.41Å; P239-K241 VanDerWaalsContact O-N 3.15Å; P239-Y242 HydrophobicContact CB-CD2 4.35Å; P239-Y242 PolarHBondContact O-N 3Å; P239-R243 PolarHBondContact O-N 2.92Å
240	A	75.4	Confident	79.2	Confident	44 Å²	44	47 Å²	47	36%	0.364	24%	0.24	S	C	.	.	H	α-helix	trans	-51.8	-45	-170	0	0	0	0	0	113.5	Y242 R243	A240-Y242 PolarHBondContact O-N 3.17Å; A240-Y242 VanDerWaalsContact O-N 3.12Å; A240-R243 PolarHBondContact O-N 3.24Å
241	K	75.5	Confident	79.1	Confident	163 Å²	163	48 Å²	48	71%	0.709	25%	0.245	S	C	*	.	H	α-helix	trans	-51.5	-32.9	177.7	-174.6	175.5	-178.3	177.1	0	114.7	P239	P239-K241 VanDerWaalsContact C-N 3.3Å; P239-K241 PolarHBondContact O-N 3.41Å; P239-K241 VanDerWaalsContact O-N 3.15Å
242	Y	77.9	Confident	79.5	Confident	90 Å²	90	48.4 Å²	48.4	35%	0.353	25%	0.249	S	C	.	.	H	α-helix	trans	-100.1	-13.5	-174.9	-64.5	-84.2	0	0	0	113.8	F116 P239 A240 A244 Y245 L246	F116-Y242 HydrophobicContact CB-CD1 4.37Å; F116-Y242 HydrophobicContact CB-CD2 3.82Å; F116-Y242 HydrophobicContact CB-CE1 4.23Å; F116-Y242 HydrophobicContact CB-CE2 3.66Å; F116-Y242 HydrophobicContact CB-CG 4.18Å; F116-Y242 HydrophobicContact CD2-CG 4.34Å; F116-Y242 HydrophobicContact CG-CD1 4.47Å; F116-Y242 HydrophobicContact CG-CG 4.43Å; P239-Y242 HydrophobicContact CB-CD2 4.35Å; P239-Y242 PolarHBondContact O-N 3Å; A240-Y242 PolarHBondContact O-N 3.17Å; A240-Y242 VanDerWaalsContact O-N 3.12Å; Y242-A244 VanDerWaalsContact C-N 3.3Å; Y242-A244 PolarHBondContact O-N 3.1Å; Y242-Y245 PolarHBondContact O-N 3.39Å; Y242-L246 PolarHBondContact O-N 2.98Å; Y242-L246 VanDerWaalsContact O-N 3.09Å
243	R	75.1	Confident	80.1	Confident	53 Å²	53	48.2 Å²	48.2	20%	0.2	25%	0.245	C	C	.	.	H	α-helix	trans	-57.4	-41.7	-178.4	-67.5	-178.8	-175.4	147.3	5.5	112.2	T235 I238 P239 A240 Y245 L246 L247	T235-R243 PolarHBondContact O-NE 3.42Å; T235-R243 VanDerWaalsContact O-NE 3.08Å; T235-R243 PolarHBondContact O-NH2 3.49Å; T235-R243 VanDerWaalsContact O-NH2 3.1Å; I238-R243 HydrophobicContact CB-CG 4.13Å; I238-R243 HydrophobicContact CG2-CB 4.47Å; I238-R243 HydrophobicContact CG2-CG 3.68Å; I238-R243 VanDerWaalsContact O-CZ 3.26Å; I238-R243 PolarHBondContact O-NE 2.9Å; I238-R243 PolarHBondContact O-NH2 3.42Å; P239-R243 PolarHBondContact O-N 2.92Å; A240-R243 PolarHBondContact O-N 3.24Å; R243-Y245 PolarHBondContact O-N 3.45Å; R243-L246 PolarHBondContact O-N 3.08Å; R243-L247 HydrophobicContact CB-CD1 4.28Å; R243-L247 WeakPolarHBondContact O-CB 3.49Å; R243-L247 VanDerWaalsContact O-CG 3.25Å; R243-L247 WeakPolarHBondContact O-CG 3.43Å; R243-L247 PolarHBondContact O-N 2.83Å
244	A	66.6	Low	80.3	Confident	75 Å²	75	50.4 Å²	50.4	62%	0.62	25%	0.254	S	S	*	.	H	α-helix	trans	-62	-26.1	-178.4	0	0	0	0	0	114.1	Y242 P248	Y242-A244 VanDerWaalsContact C-N 3.3Å; Y242-A244 PolarHBondContact O-N 3.1Å; A244-P248 WeakPolarHBondContact O-CD 3.43Å; A244-P248 WeakPolarHBondContact O-CG 2.99Å
245	Y	73.1	Confident	80.7	Confident	180 Å²	180	51.1 Å²	51.1	71%	0.706	26%	0.257	S	S	*	.	H	α-helix	trans	-94.9	-40.3	179.1	-58.5	-80.1	0	0	0	112.3	Y242 R243 L249	Y242-Y245 PolarHBondContact O-N 3.39Å; R243-Y245 PolarHBondContact O-N 3.45Å; Y245-L249 WeakPolarHBondContact O-CB 3.38Å; Y245-L249 PolarHBondContact O-N 3.46Å
246	L	76.2	Confident	81.3	Confident	18 Å²	18	52.2 Å²	52.2	9%	0.094	26%	0.264	C	S	.	.	H	α-helix	trans	-74.1	-33.4	-176.6	-73.8	158.6	0	0	0	113.2	F116 F124 I238 Y242 R243 L249 G250	F116-L246 HydrophobicContact CD2-CD1 4.12Å; F116-L246 HydrophobicContact CE2-CD1 3.61Å; F116-L246 HydrophobicContact CE2-CD2 4.34Å; F124-L246 HydrophobicContact CD1-CD2 4.32Å; F124-L246 HydrophobicContact CD2-CB 4.42Å; F124-L246 HydrophobicContact CD2-CD2 3.67Å; F124-L246 HydrophobicContact CE2-CB 4.32Å; F124-L246 HydrophobicContact CE2-CD2 3.9Å; F124-L246 WeakPolarHBondContact CE2-O 3.47Å; F124-L246 HydrophobicContact CG-CD2 3.9Å; F124-L246 HydrophobicContact CZ-CD2 4.31Å; I238-L246 HydrophobicContact CD1-CB 4.36Å; I238-L246 HydrophobicContact CD1-CD1 4.17Å; I238-L246 HydrophobicContact CG1-CD1 4.36Å; I238-L246 HydrophobicContact CG2-CD1 3.66Å; Y242-L246 PolarHBondContact O-N 2.98Å; Y242-L246 VanDerWaalsContact O-N 3.09Å; R243-L246 PolarHBondContact O-N 3.08Å; L246-L249 PolarHBondContact O-N 3.28Å; L246-G250 PolarHBondContact O-N 3.06Å
247	L	73.3	Confident	81.9	Confident	56 Å²	56	51 Å²	51	29%	0.293	26%	0.258	S	S	.	.	H	α-helix	trans	-68.9	-46.4	-178.1	-63.6	174.3	0	0	0	112.6	F231 T235 R243 L249 G250	F231-L247 HydrophobicContact CE2-CD2 3.83Å; F231-L247 HydrophobicContact CZ-CD1 4.33Å; F231-L247 HydrophobicContact CZ-CD2 4.07Å; T235-L247 HydrophobicContact CG2-CD1 4.1Å; T235-L247 HydrophobicContact CG2-CD2 3.94Å; R243-L247 HydrophobicContact CB-CD1 4.28Å; R243-L247 WeakPolarHBondContact O-CB 3.49Å; R243-L247 VanDerWaalsContact O-CG 3.25Å; R243-L247 WeakPolarHBondContact O-CG 3.43Å; R243-L247 PolarHBondContact O-N 2.83Å; L247-L249 VanDerWaalsContact C-N 3.32Å; L247-L249 PolarHBondContact O-N 2.88Å; L247-G250 WeakPolarHBondContact O-CA 3.32Å; L247-G250 PolarHBondContact O-N 3.43Å
248	P	72.9	Confident	82.3	Confident	24 Å²	24	50.8 Å²	50.8	16%	0.156	26%	0.258	C	S	.	.	H	α-helix	trans	-63.4	-34.8	172.2	-23.7	35.6	0	0	0	113.2	A244 G250 T251	A244-P248 WeakPolarHBondContact O-CD 3.43Å; A244-P248 WeakPolarHBondContact O-CG 2.99Å; P248-G250 PolarHBondContact O-N 2.99Å; P248-G250 VanDerWaalsContact O-N 3.12Å; P248-T251 WeakPolarHBondContact O-CG2 3.49Å; P248-T251 PolarHBondContact O-N 3.15Å; P248-T251 VanDerWaalsContact O-N 3.08Å; P248-T251 PolarHBondContact O-OG1 2.95Å
249	L	80	Confident	82.8	Confident	81 Å²	81	51.8 Å²	51.8	42%	0.424	26%	0.263	S	S	.	.	H	α-helix	trans	-62	-19.7	174.5	-164.1	68.8	0	0	0	112.3	F124 Y245 L246 L247 T251 I252	F124-L249 HydrophobicContact CE1-CD2 3.68Å; F124-L249 HydrophobicContact CE1-CG 4.18Å; F124-L249 HydrophobicContact CE2-CB 4.49Å; F124-L249 HydrophobicContact CZ-CB 3.85Å; F124-L249 HydrophobicContact CZ-CD2 3.57Å; F124-L249 HydrophobicContact CZ-CG 3.71Å; Y245-L249 WeakPolarHBondContact O-CB 3.38Å; Y245-L249 PolarHBondContact O-N 3.46Å; L246-L249 PolarHBondContact O-N 3.28Å; L247-L249 VanDerWaalsContact C-N 3.32Å; L247-L249 PolarHBondContact O-N 2.88Å; L249-T251 PolarHBondContact O-N 3.45Å; L249-I252 HydrophobicContact CD1-CD1 3.56Å; L249-I252 HydrophobicContact CD1-CG1 4.47Å; L249-I252 HydrophobicContact CG-CD1 4.42Å; L249-I252 PolarHBondContact O-N 2.89Å
250	G	79.4	Confident	83.4	Confident	11 Å²	11	54.3 Å²	54.3	11%	0.113	28%	0.275	C	S	.	.	H	α-helix	trans	-64	-17.6	172.8	0	0	0	0	0	115.4	L246 L247 P248 I252	L246-G250 PolarHBondContact O-N 3.06Å; L247-G250 WeakPolarHBondContact O-CA 3.32Å; L247-G250 PolarHBondContact O-N 3.43Å; P248-G250 PolarHBondContact O-N 2.99Å; P248-G250 VanDerWaalsContact O-N 3.12Å; G250-I252 VanDerWaalsContact C-N 3.32Å
251	T	83.2	Confident	84.4	Confident	23 Å²	23	52.2 Å²	52.2	14%	0.141	26%	0.258	C	S	.	.	H	α-helix	trans	-71	-28.6	176.9	61.6	0	0	0	0	112.2	P248 L249 F253 W254 M255 N483	P248-T251 WeakPolarHBondContact O-CG2 3.49Å; P248-T251 PolarHBondContact O-N 3.15Å; P248-T251 VanDerWaalsContact O-N 3.08Å; P248-T251 PolarHBondContact O-OG1 2.95Å; L249-T251 PolarHBondContact O-N 3.45Å; T251-F253 VanDerWaalsContact C-N 3.28Å; T251-F253 PolarHBondContact O-N 3.23Å; T251-W254 WeakPolarHBondContact O-CB 3.5Å; T251-W254 PolarHBondContact O-N 2.89Å; T251-W254 VanDerWaalsContact O-N 3.08Å; T251-M255 PolarHBondContact O-N 3.45Å; T251-N483 VanDerWaalsContact CG2-OD1 3.23Å; T251-N483 WeakPolarHBondContact CG2-OD1 3.38Å
252	I	89.8	Confident	85.4	Confident	69 Å²	69	44.9 Å²	44.9	35%	0.354	23%	0.227	S	C	.	.	H	α-helix	trans	-58.6	-43.9	176.8	-58.5	-175	0	0	0	109.9	L249 G250 W254 M255 T256 V425	L249-I252 HydrophobicContact CD1-CD1 3.56Å; L249-I252 HydrophobicContact CD1-CG1 4.47Å; L249-I252 HydrophobicContact CG-CD1 4.42Å; L249-I252 PolarHBondContact O-N 2.89Å; G250-I252 VanDerWaalsContact C-N 3.32Å; I252-W254 VanDerWaalsContact C-N 3.33Å; I252-W254 PolarHBondContact O-N 3.48Å; I252-M255 PolarHBondContact O-N 3.36Å; I252-T256 PolarHBondContact O-N 3.1Å; I252-T256 PolarHBondContact O-OG1 3.37Å; I252-V425 HydrophobicContact CG1-CG1 4.08Å; I252-V425 HydrophobicContact CG1-CG2 4.32Å
253	F	92.3	Very high	86.3	Confident	38 Å²	38	44 Å²	44	17%	0.167	23%	0.227	C	C	.	.	H	α-helix	trans	-63.8	-36.1	176.6	-66.3	-67.8	0	0	0	113.2	F124 G128 N131 I132 T251 T256 G257	F124-F253 HydrophobicContact CD1-CE2 4.2Å; F124-F253 HydrophobicContact CD1-CZ 4.39Å; F124-F253 AromaticContact CE1-CE2 3.58Å; F124-F253 HydrophobicContact CE1-CE2 3.58Å; F124-F253 AromaticContact CE1-CZ 3.99Å; F124-F253 HydrophobicContact CE1-CZ 3.99Å; F124-F253 HydrophobicContact CE2-CE2 4.17Å; F124-F253 HydrophobicContact CZ-CD2 4.4Å; F124-F253 AromaticContact CZ-CE2 3.56Å; F124-F253 HydrophobicContact CZ-CE2 3.56Å; F124-F253 HydrophobicContact CZ-CZ 4.42Å; G128-F253 VanDerWaalsContact C-CD1 3.46Å; G128-F253 VanDerWaalsContact C-CG 3.41Å; G128-F253 WeakPolarHBondContact O-CB 3.41Å; G128-F253 VanDerWaalsContact O-CG 3.24Å; G128-F253 WeakPolarHBondContact O-CG 3.42Å; N131-F253 HydrophobicContact CB-CB 3.92Å; I132-F253 WeakPolarHBondContact CA-O 3.48Å; I132-F253 HydrophobicContact CD1-CD1 4.02Å; I132-F253 HydrophobicContact CG1-CB 3.99Å; I132-F253 HydrophobicContact CG1-CD1 4Å; I132-F253 HydrophobicContact CG1-CG 4.49Å; I132-F253 WeakPolarHBondContact CG1-O 3.41Å; T251-F253 VanDerWaalsContact C-N 3.28Å; T251-F253 PolarHBondContact O-N 3.23Å; F253-T256 PolarHBondContact O-N 3.48Å; F253-G257 PolarHBondContact O-N 3.17Å
254	W	91.6	Very high	87.3	Confident	47 Å²	47	43 Å²	43	18%	0.178	23%	0.226	C	C	.	.	H	α-helix	trans	-64.4	-47.3	175.4	-174.7	-81	0	0	0	111	E134 A135 I138 T251 I252 T256 G257 S258 Y368	E134-W254 HydrophobicContact CG-CH2 4.44Å; E134-W254 HydrophobicContact CG-CZ3 3.84Å; A135-W254 HydrophobicContact CB-CB 4.4Å; A135-W254 HydrophobicContact CB-CD2 3.61Å; A135-W254 HydrophobicContact CB-CE3 3.88Å; A135-W254 HydrophobicContact CB-CG 3.86Å; A135-W254 HydrophobicContact CB-CZ2 4.46Å; A135-W254 HydrophobicContact CB-CZ3 4.42Å; A135-W254 VanDerWaalsContact CB-O 3.28Å; A135-W254 WeakPolarHBondContact CB-O 3.43Å; I138-W254 HydrophobicContact CD1-CH2 3.72Å; I138-W254 HydrophobicContact CD1-CZ3 4.43Å; T251-W254 WeakPolarHBondContact O-CB 3.5Å; T251-W254 PolarHBondContact O-N 2.89Å; T251-W254 VanDerWaalsContact O-N 3.08Å; I252-W254 VanDerWaalsContact C-N 3.33Å; I252-W254 PolarHBondContact O-N 3.48Å; W254-T256 VanDerWaalsContact C-N 3.35Å; W254-T256 PolarHBondContact O-N 3.14Å; W254-G257 PolarHBondContact O-N 3.41Å; W254-G257 VanDerWaalsContact O-N 3.1Å; W254-S258 PolarHBondContact O-N 3.06Å; W254-Y368 HydrophobicContact CZ2-CE1 4.17Å; W254-Y368 AromaticContact NE1-CZ 3.67Å; W254-Y368 PolarHBondContact NE1-OH 2.87Å
255	M	93.1	Very high	88.6	Confident	29 Å²	29	39.4 Å²	39.4	14%	0.143	20%	0.196	C	C	.	.	H	α-helix	trans	-62.1	-39	174.5	-177	-132.9	68.6	0	0	112.2	T251 I252 G257 S258 M259 L422 E424 V425	T251-M255 PolarHBondContact O-N 3.45Å; I252-M255 PolarHBondContact O-N 3.36Å; M255-G257 VanDerWaalsContact C-N 3.27Å; M255-G257 PolarHBondContact O-N 3.4Å; M255-S258 WeakPolarHBondContact CA-OG 3.44Å; M255-S258 PolarHBondContact O-N 2.97Å; M255-S258 PolarHBondContact O-OG 3.15Å; M255-M259 HydrophobicContact CE-CG 4.39Å; M255-M259 HydrophobicContact CG-CG 4.44Å; M255-M259 WeakPolarHBondContact O-CB 3.5Å; M255-M259 WeakPolarHBondContact O-CG 3.29Å; M255-M259 PolarHBondContact O-N 2.99Å; M255-L422 HydrophobicContact SD-CD2 4.2Å; M255-E424 HydrophobicContact CB-CB 4.42Å; M255-E424 HydrophobicContact CG-CB 4.39Å; M255-V425 HydrophobicContact CB-CG2 3.55Å; M255-V425 HydrophobicContact CG-CG2 3.86Å; M255-V425 HydrophobicContact SD-CB 3.92Å; M255-V425 HydrophobicContact SD-CG2 3.61Å
256	T	94.8	Very high	89.6	Confident	54 Å²	54	33.2 Å²	33.2	33%	0.331	18%	0.175	S	C	.	.	H	α-helix	trans	-61.5	-37.6	173.5	-57.9	0	0	0	0	111.4	I132 I252 F253 W254 L260	I132-T256 HydrophobicContact CD1-CG2 4.02Å; I132-T256 HydrophobicContact CG1-CG2 4.36Å; I252-T256 PolarHBondContact O-N 3.1Å; I252-T256 PolarHBondContact O-OG1 3.37Å; F253-T256 PolarHBondContact O-N 3.48Å; W254-T256 VanDerWaalsContact C-N 3.35Å; W254-T256 PolarHBondContact O-N 3.14Å; T256-L260 VanDerWaalsContact O-CB 3.24Å; T256-L260 WeakPolarHBondContact O-CB 3.36Å; T256-L260 PolarHBondContact O-N 3.19Å
257	G	95.4	Very high	90.5	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-68.8	-44.1	175.3	0	0	0	0	0	113.6	I132 M136 F253 W254 M255 M259 L260 I261	I132-G257 WeakPolarHBondContact O-CA 3.19Å; M136-G257 VanDerWaalsContact CG-O 3.25Å; M136-G257 WeakPolarHBondContact CG-O 3.5Å; F253-G257 PolarHBondContact O-N 3.17Å; W254-G257 PolarHBondContact O-N 3.41Å; W254-G257 VanDerWaalsContact O-N 3.1Å; M255-G257 VanDerWaalsContact C-N 3.27Å; M255-G257 PolarHBondContact O-N 3.4Å; G257-M259 VanDerWaalsContact C-N 3.34Å; G257-M259 PolarHBondContact O-N 2.63Å; G257-L260 PolarHBondContact O-N 3.14Å; G257-I261 PolarHBondContact O-N 3.23Å; G257-I261 VanDerWaalsContact O-N 3.14Å
258	S	94.4	Very high	91.6	Very high	1 Å²	1	35.2 Å²	35.2	1%	0.007	19%	0.185	C	C	.	.	H	α-helix	trans	-62.8	-41.1	175.5	66.3	0	0	0	0	111.5	W254 M255 I261 I262 E424	W254-S258 PolarHBondContact O-N 3.06Å; M255-S258 WeakPolarHBondContact CA-OG 3.44Å; M255-S258 PolarHBondContact O-N 2.97Å; M255-S258 PolarHBondContact O-OG 3.15Å; S258-I261 WeakPolarHBondContact O-CG2 3.44Å; S258-I262 WeakPolarHBondContact O-CD1 3.36Å; S258-I262 VanDerWaalsContact O-CG1 3.27Å; S258-I262 WeakPolarHBondContact O-CG1 3.4Å; S258-I262 PolarHBondContact O-N 3.38Å; S258-E424 PolarHBondContact OG-OE2 3.45Å
259	M	95.4	Very high	92.6	Very high	27 Å²	27	34.6 Å²	34.6	13%	0.133	18%	0.181	C	C	.	.	H	α-helix	trans	-63.5	-44.7	172.5	-68	-69.4	79.7	0	0	113.6	M255 G257 I261 I262 L263 L418 L422	M255-M259 HydrophobicContact CE-CG 4.39Å; M255-M259 HydrophobicContact CG-CG 4.44Å; M255-M259 WeakPolarHBondContact O-CB 3.5Å; M255-M259 WeakPolarHBondContact O-CG 3.29Å; M255-M259 PolarHBondContact O-N 2.99Å; G257-M259 VanDerWaalsContact C-N 3.34Å; G257-M259 PolarHBondContact O-N 2.63Å; M259-I261 VanDerWaalsContact C-N 3.34Å; M259-I261 PolarHBondContact O-N 2.86Å; M259-I262 HydrophobicContact CE-CD1 3.75Å; M259-I262 PolarHBondContact O-N 2.82Å; M259-L263 VanDerWaalsContact O-CB 3.28Å; M259-L263 WeakPolarHBondContact O-CB 3.35Å; M259-L263 PolarHBondContact O-N 2.67Å; M259-L418 VanDerWaalsContact CE-CA 3.5Å; M259-L418 HydrophobicContact CE-CB 4.41Å; M259-L418 HydrophobicContact CE-CD2 3.87Å; M259-L418 VanDerWaalsContact CE-O 3.26Å; M259-L418 WeakPolarHBondContact CE-O 3.42Å; M259-L418 HydrophobicContact SD-CB 4.42Å; M259-L418 HydrophobicContact SD-CD2 3.88Å; M259-L422 HydrophobicContact SD-CD2 4.12Å; M259-L422 HydrophobicContact SD-CG 4.37Å
260	L	96.3	Very high	93.1	Very high	57 Å²	57	35.1 Å²	35.1	30%	0.298	19%	0.19	S	C	.	.	H	α-helix	trans	-64.4	-38	-176.8	-175.7	56.2	0	0	0	111.9	I132 M136 T256 G257 L264 P284	I132-L260 HydrophobicContact CG2-CD2 4.39Å; M136-L260 HydrophobicContact CE-CB 4.49Å; M136-L260 HydrophobicContact CE-CD2 3.92Å; M136-L260 HydrophobicContact CE-CG 3.92Å; M136-L260 HydrophobicContact SD-CB 4.35Å; M136-L260 HydrophobicContact SD-CD2 3.7Å; M136-L260 HydrophobicContact SD-CG 4.13Å; T256-L260 VanDerWaalsContact O-CB 3.24Å; T256-L260 WeakPolarHBondContact O-CB 3.36Å; T256-L260 PolarHBondContact O-N 3.19Å; G257-L260 PolarHBondContact O-N 3.14Å; L260-L264 HydrophobicContact CD1-CG 4.49Å; L260-L264 HydrophobicContact CG-CD1 4.39Å; L260-L264 WeakPolarHBondContact O-CB 3.44Å; L260-L264 VanDerWaalsContact O-CG 3.26Å; L260-L264 WeakPolarHBondContact O-CG 3.28Å; L260-L264 PolarHBondContact O-N 3.33Å; L260-P284 HydrophobicContact CD2-CG 4.35Å
261	I	96.5	Very high	93.7	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-73.5	-35.6	177.7	-168.2	57.3	0	0	0	113	M136 M139 L140 G257 S258 M259 L264 G265 M277	M136-I261 HydrophobicContact CB-CB 4.44Å; M136-I261 HydrophobicContact CG-CB 4.3Å; M139-I261 HydrophobicContact CB-CG2 3.85Å; L140-I261 HydrophobicContact CB-CD1 4.34Å; L140-I261 HydrophobicContact CB-CG1 3.99Å; L140-I261 HydrophobicContact CD1-CD1 3.72Å; L140-I261 HydrophobicContact CD1-CG1 4.3Å; L140-I261 HydrophobicContact CG-CD1 3.97Å; L140-I261 HydrophobicContact CG-CG1 4.12Å; G257-I261 PolarHBondContact O-N 3.23Å; G257-I261 VanDerWaalsContact O-N 3.14Å; S258-I261 WeakPolarHBondContact O-CG2 3.44Å; M259-I261 VanDerWaalsContact C-N 3.34Å; M259-I261 PolarHBondContact O-N 2.86Å; I261-L264 PolarHBondContact O-N 3.41Å; I261-G265 PolarHBondContact O-N 3.14Å; I261-M277 HydrophobicContact CD1-CE 4.04Å; I261-M277 HydrophobicContact CD1-CG 4.33Å; I261-M277 HydrophobicContact CD1-SD 4.12Å
262	I	95.9	Very high	94.2	Very high	10 Å²	10	43.2 Å²	43.2	5%	0.051	23%	0.232	C	C	.	.	H	α-helix	trans	-67.7	-40.5	174.6	-63.1	162.8	0	0	0	110.5	V143 S258 M259 G265 M266 Y414 L417 L418	V143-I262 HydrophobicContact CG2-CG1 4.03Å; S258-I262 WeakPolarHBondContact O-CD1 3.36Å; S258-I262 VanDerWaalsContact O-CG1 3.27Å; S258-I262 WeakPolarHBondContact O-CG1 3.4Å; S258-I262 PolarHBondContact O-N 3.38Å; M259-I262 HydrophobicContact CE-CD1 3.75Å; M259-I262 PolarHBondContact O-N 2.82Å; I262-G265 WeakPolarHBondContact O-CA 3.46Å; I262-G265 PolarHBondContact O-N 3.28Å; I262-M266 PolarHBondContact O-N 2.97Å; I262-Y414 HydrophobicContact CG2-CD1 4.07Å; I262-L417 HydrophobicContact CD1-CB 4.09Å; I262-L417 HydrophobicContact CG2-CB 3.91Å; I262-L418 HydrophobicContact CB-CD2 3.94Å; I262-L418 HydrophobicContact CB-CG 4.5Å; I262-L418 HydrophobicContact CG2-CD2 3.7Å; I262-L418 HydrophobicContact CG2-CG 3.71Å
263	L	96.1	Very high	94.3	Very high	70 Å²	70	41 Å²	41	37%	0.366	23%	0.225	S	C	.	.	H	α-helix	trans	-64	-43.1	175	-178.3	60.1	0	0	0	112.2	M259 G265 M266 L267 L418	M259-L263 VanDerWaalsContact O-CB 3.28Å; M259-L263 WeakPolarHBondContact O-CB 3.35Å; M259-L263 PolarHBondContact O-N 2.67Å; L263-G265 VanDerWaalsContact C-N 3.28Å; L263-G265 PolarHBondContact O-N 2.9Å; L263-M266 HydrophobicContact CD1-CE 3.75Å; L263-M266 PolarHBondContact O-N 3.45Å; L263-L267 HydrophobicContact CD1-CD1 3.92Å; L263-L267 HydrophobicContact CD1-CG 4.24Å; L263-L267 HydrophobicContact CG-CD1 4.06Å; L263-L267 WeakPolarHBondContact O-CG 3.28Å; L263-L267 PolarHBondContact O-N 3.09Å; L263-L267 VanDerWaalsContact O-N 3.11Å; L263-L418 HydrophobicContact CB-CD2 4.43Å
264	L	96.1	Very high	94.4	Very high	32 Å²	32	39.5 Å²	39.5	17%	0.168	22%	0.218	C	C	.	.	H	α-helix	trans	-60.8	-39.6	171.7	-75.9	171.5	0	0	0	111.1	M136 L260 I261 L267 V268 M277 L280	M136-L264 HydrophobicContact CE-CD1 3.87Å; L260-L264 HydrophobicContact CD1-CG 4.49Å; L260-L264 HydrophobicContact CG-CD1 4.39Å; L260-L264 WeakPolarHBondContact O-CB 3.44Å; L260-L264 VanDerWaalsContact O-CG 3.26Å; L260-L264 WeakPolarHBondContact O-CG 3.28Å; L260-L264 PolarHBondContact O-N 3.33Å; I261-L264 PolarHBondContact O-N 3.41Å; L264-L267 PolarHBondContact O-N 3.06Å; L264-V268 HydrophobicContact CD2-CG2 4.34Å; L264-V268 WeakPolarHBondContact O-CB 3.18Å; L264-V268 VanDerWaalsContact O-CG2 3.3Å; L264-V268 WeakPolarHBondContact O-CG2 3.29Å; L264-V268 PolarHBondContact O-N 3.47Å; L264-M277 HydrophobicContact CB-CG 3.95Å; L264-L280 HydrophobicContact CD2-CB 4.33Å
265	G	94.9	Very high	94.6	Very high	0 Å²	0	40.4 Å²	40.4	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-52.9	-59.4	171	0	0	0	0	0	112.3	I261 I262 L263 L267 V268 V269 P270 M277	I261-G265 PolarHBondContact O-N 3.14Å; I262-G265 WeakPolarHBondContact O-CA 3.46Å; I262-G265 PolarHBondContact O-N 3.28Å; L263-G265 VanDerWaalsContact C-N 3.28Å; L263-G265 PolarHBondContact O-N 2.9Å; G265-L267 VanDerWaalsContact C-N 3.28Å; G265-L267 PolarHBondContact O-N 2.91Å; G265-V268 PolarHBondContact O-N 2.89Å; G265-V269 VanDerWaalsContact O-CB 3.27Å; G265-V269 WeakPolarHBondContact O-CB 3.49Å; G265-V269 WeakPolarHBondContact O-CG2 3.26Å; G265-V269 PolarHBondContact O-N 3.14Å; G265-P270 WeakPolarHBondContact O-CD 3.41Å; G265-M277 WeakPolarHBondContact CA-SD 3.44Å; G265-M277 PolarHBondContact N-SD 2.7Å
266	M	94.8	Very high	94.7	Very high	50 Å²	50	45 Å²	45	25%	0.246	24%	0.238	C	C	.	.	H	α-helix	trans	-56.7	-36.9	-177.6	-168.3	177	66.5	0	0	113.8	I262 L263 Y414 L418	I262-M266 PolarHBondContact O-N 2.97Å; L263-M266 HydrophobicContact CD1-CE 3.75Å; L263-M266 PolarHBondContact O-N 3.45Å; M266-Y414 HydrophobicContact CB-CD1 3.95Å; M266-Y414 HydrophobicContact CB-CD2 4.09Å; M266-Y414 HydrophobicContact CB-CG 3.68Å; M266-Y414 HydrophobicContact CG-CD2 4.14Å; M266-Y414 HydrophobicContact CG-CG 3.97Å; M266-L418 HydrophobicContact CE-CD1 4.14Å; M266-L418 HydrophobicContact SD-CD1 4.18Å
267	L	95.3	Very high	94.8	Very high	107 Å²	107	42.4 Å²	42.4	56%	0.56	22%	0.222	S	C	*	.	H	α-helix	trans	-89.1	-33.1	-175.9	-63.5	175.2	0	0	0	113.8	L263 L264 G265 T271	L263-L267 HydrophobicContact CD1-CD1 3.92Å; L263-L267 HydrophobicContact CD1-CG 4.24Å; L263-L267 HydrophobicContact CG-CD1 4.06Å; L263-L267 WeakPolarHBondContact O-CG 3.28Å; L263-L267 PolarHBondContact O-N 3.09Å; L263-L267 VanDerWaalsContact O-N 3.11Å; L264-L267 PolarHBondContact O-N 3.06Å; G265-L267 VanDerWaalsContact C-N 3.28Å; G265-L267 PolarHBondContact O-N 2.91Å; L267-T271 PolarHBondContact O-OG1 3.11Å
268	V	95.9	Very high	94.8	Very high	9 Å²	9	42.5 Å²	42.5	6%	0.055	22%	0.222	C	C	.	.	H	α-helix	trans	-104.5	-37.9	-168.1	-179.8	0	0	0	0	112.6	L264 G265 T271 M272 G273 W276 M277 L280	L264-V268 HydrophobicContact CD2-CG2 4.34Å; L264-V268 WeakPolarHBondContact O-CB 3.18Å; L264-V268 VanDerWaalsContact O-CG2 3.3Å; L264-V268 WeakPolarHBondContact O-CG2 3.29Å; L264-V268 PolarHBondContact O-N 3.47Å; G265-V268 PolarHBondContact O-N 2.89Å; V268-T271 PolarHBondContact O-N 3.23Å; V268-T271 PolarHBondContact O-OG1 3.48Å; V268-M272 HydrophobicContact CG1-CB 4.16Å; V268-M272 HydrophobicContact CG1-CE 3.89Å; V268-M272 HydrophobicContact CG2-CE 4.43Å; V268-M272 PolarHBondContact O-N 3.11Å; V268-G273 PolarHBondContact O-N 3.4Å; V268-W276 HydrophobicContact CG1-CB 3.94Å; V268-M277 HydrophobicContact CB-CB 4.27Å; V268-M277 HydrophobicContact CG1-CB 4.04Å; V268-L280 HydrophobicContact CG1-CD1 4.17Å; V268-L280 HydrophobicContact CG2-CD1 3.72Å
269	V	93.6	Very high	94.9	Very high	11 Å²	11	45.2 Å²	45.2	7%	0.067	23%	0.232	C	C	.	.	H	α-helix	trans	-63.2	-46.6	-175.1	175.7	0	0	0	0	111.9	E147 G265 T271 G273 M277	E147-V269 HydrophobicContact CG-CG1 3.78Å; E147-V269 WeakPolarHBondContact OE1-CG1 3.44Å; E147-V269 WeakPolarHBondContact OE2-CG1 3.41Å; G265-V269 VanDerWaalsContact O-CB 3.27Å; G265-V269 WeakPolarHBondContact O-CB 3.49Å; G265-V269 WeakPolarHBondContact O-CG2 3.26Å; G265-V269 PolarHBondContact O-N 3.14Å; V269-T271 PolarHBondContact O-N 3.29Å; V269-G273 VanDerWaalsContact O-CA 3.24Å; V269-G273 WeakPolarHBondContact O-CA 3.42Å; V269-G273 PolarHBondContact O-N 2.94Å; V269-M277 HydrophobicContact CG2-CB 4.26Å; V269-M277 HydrophobicContact CG2-SD 3.81Å
270	P	90.1	Very high	94.9	Very high	93 Å²	93	47 Å²	47	60%	0.604	24%	0.242	S	C	*	.	H	α-helix	trans	-66.2	-20.1	-179.2	-22.7	35	0	0	0	115.1	G265	G265-P270 WeakPolarHBondContact O-CD 3.41Å
271	T	91.6	Very high	94.8	Very high	107 Å²	107	44.3 Å²	44.3	66%	0.656	23%	0.228	S	C	*	.	H	α-helix	trans	-109.8	-36.5	-172.4	54.9	0	0	0	0	113.6	L267 V268 V269	L267-T271 PolarHBondContact O-OG1 3.11Å; V268-T271 PolarHBondContact O-N 3.23Å; V268-T271 PolarHBondContact O-OG1 3.48Å; V269-T271 PolarHBondContact O-N 3.29Å
272	M	93.6	Very high	94.8	Very high	97 Å²	97	44.5 Å²	44.5	48%	0.478	23%	0.229	S	C	.	.	H	α-helix	trans	-129.1	-6.6	-174.5	-61.8	-171.9	-74.9	0	0	113.3	V268 W276 L280	V268-M272 HydrophobicContact CG1-CB 4.16Å; V268-M272 HydrophobicContact CG1-CE 3.89Å; V268-M272 HydrophobicContact CG2-CE 4.43Å; V268-M272 PolarHBondContact O-N 3.11Å; M272-W276 HydrophobicContact CB-CB 3.78Å; M272-W276 HydrophobicContact CB-CG 3.94Å; M272-L280 HydrophobicContact CE-CD1 4.45Å
273	G	92.5	Very high	94.6	Very high	21 Å²	21	47.4 Å²	47.4	22%	0.216	25%	0.247	C	C	.	.			trans	76.7	166.8	179.1	0	0	0	0	0	115.1	V268 V269 R275 W276 M277	V268-G273 PolarHBondContact O-N 3.4Å; V269-G273 VanDerWaalsContact O-CA 3.24Å; V269-G273 WeakPolarHBondContact O-CA 3.42Å; V269-G273 PolarHBondContact O-N 2.94Å; G273-R275 VanDerWaalsContact C-N 3.26Å; G273-R275 PolarHBondContact O-N 3.24Å; G273-R275 VanDerWaalsContact O-N 3.16Å; G273-W276 PolarHBondContact O-N 2.93Å; G273-W276 VanDerWaalsContact O-N 3.16Å; G273-M277 PolarHBondContact O-N 3.39Å
274	W	94	Very high	94.5	Very high	7 Å²	7	45.8 Å²	45.8	3%	0.027	24%	0.241	C	C	.	.	H	α-helix	trans	-56.4	-32.6	-174.2	67.2	-92.6	0	0	0	114.8	V144 E147 I148 W152 F213 W276 M277 I278	V144-W274 HydrophobicContact CG1-CE3 4.34Å; V144-W274 HydrophobicContact CG2-CB 4.47Å; E147-W274 HydrophobicContact CB-CB 3.85Å; E147-W274 HydrophobicContact CB-CG 3.89Å; E147-W274 HydrophobicContact CG-CB 4.1Å; I148-W274 HydrophobicContact CG2-CD2 4.45Å; I148-W274 HydrophobicContact CG2-CZ2 4.23Å; W152-W274 AromaticContact CH2-CH2 3.96Å; W152-W274 HydrophobicContact CH2-CH2 3.96Å; W152-W274 HydrophobicContact CH2-CZ2 4.07Å; W152-W274 HydrophobicContact CZ2-CZ2 4.43Å; F213-W274 HydrophobicContact CD2-CH2 4.09Å; F213-W274 HydrophobicContact CD2-CZ3 4.21Å; F213-W274 HydrophobicContact CE2-CE3 4.48Å; F213-W274 AromaticContact CE2-CH2 3.92Å; F213-W274 HydrophobicContact CE2-CH2 3.92Å; F213-W274 AromaticContact CE2-CZ3 3.64Å; F213-W274 HydrophobicContact CE2-CZ3 3.64Å; W274-W276 VanDerWaalsContact C-N 3.32Å; W274-W276 PolarHBondContact O-N 3.18Å; W274-M277 WeakPolarHBondContact O-CB 3.29Å; W274-M277 PolarHBondContact O-N 3.49Å; W274-I278 HydrophobicContact CE3-CD1 3.62Å; W274-I278 HydrophobicContact CE3-CG1 4.43Å; W274-I278 HydrophobicContact CZ3-CD1 3.71Å; W274-I278 PolarHBondContact O-N 2.77Å; W274-I278 VanDerWaalsContact O-N 3.09Å
275	R	96.1	Very high	94.3	Very high	67 Å²	67	44.3 Å²	44.3	25%	0.253	23%	0.234	S	C	.	.	H	α-helix	trans	-62	-39.1	179.9	-68.8	-178.4	173.5	103.1	-5	112	E151 S205 G273 R279	E151-R275 VanDerWaalsContact CD-NH1 3.26Å; E151-R275 IonicContact OE1-CZ 2.77Å; E151-R275 IonicContact OE1-NH1 3.43Å; E151-R275 PolarHBondContact OE1-NH1 2.83Å; E151-R275 IonicContact OE1-NH2 3.05Å; E151-R275 PolarHBondContact OE1-NH2 3.46Å; E151-R275 IonicContact OE2-NH1 3.25Å; E151-R275 PolarHBondContact OE2-NH1 3.44Å; S205-R275 WeakPolarHBondContact CB-O 3.24Å; G273-R275 VanDerWaalsContact C-N 3.26Å; G273-R275 PolarHBondContact O-N 3.24Å; G273-R275 VanDerWaalsContact O-N 3.16Å; R275-R279 WeakPolarHBondContact O-CG 3.39Å; R275-R279 PolarHBondContact O-N 3.06Å
276	W	96.1	Very high	94.1	Very high	125 Å²	125	48.5 Å²	48.5	47%	0.473	26%	0.255	S	S	.	.	H	α-helix	trans	-74	-33.7	175.6	-83.6	106	0	0	0	112.5	V268 M272 G273 W274 I278 R279 L280	V268-W276 HydrophobicContact CG1-CB 3.94Å; M272-W276 HydrophobicContact CB-CB 3.78Å; M272-W276 HydrophobicContact CB-CG 3.94Å; G273-W276 PolarHBondContact O-N 2.93Å; G273-W276 VanDerWaalsContact O-N 3.16Å; W274-W276 VanDerWaalsContact C-N 3.32Å; W274-W276 PolarHBondContact O-N 3.18Å; W276-I278 VanDerWaalsContact C-N 3.34Å; W276-I278 PolarHBondContact O-N 3.23Å; W276-R279 VanDerWaalsContact CE2-NH1 3.34Å; W276-R279 HydrophobicContact CE3-CB 4.41Å; W276-R279 PolarHBondContact O-N 3.34Å; W276-L280 WeakPolarHBondContact O-CG 3.5Å; W276-L280 PolarHBondContact O-N 3.42Å
277	M	95.9	Very high	94	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-57.8	-45.7	173.4	-170.6	-166.2	67.9	0	0	111.5	L140 V143 V144 I261 L264 G265 V268 V269 G273 W274 R279 L280 S281	L140-M277 HydrophobicContact CG-CE 4.11Å; V143-M277 HydrophobicContact CB-CE 4.41Å; V143-M277 HydrophobicContact CG1-CE 3.92Å; V143-M277 HydrophobicContact CG1-SD 3.66Å; V144-M277 HydrophobicContact CG2-CE 3.29Å; I261-M277 HydrophobicContact CD1-CE 4.04Å; I261-M277 HydrophobicContact CD1-CG 4.33Å; I261-M277 HydrophobicContact CD1-SD 4.12Å; L264-M277 HydrophobicContact CB-CG 3.95Å; G265-M277 WeakPolarHBondContact CA-SD 3.44Å; G265-M277 PolarHBondContact N-SD 2.7Å; V268-M277 HydrophobicContact CB-CB 4.27Å; V268-M277 HydrophobicContact CG1-CB 4.04Å; V269-M277 HydrophobicContact CG2-CB 4.26Å; V269-M277 HydrophobicContact CG2-SD 3.81Å; G273-M277 PolarHBondContact O-N 3.39Å; W274-M277 WeakPolarHBondContact O-CB 3.29Å; W274-M277 PolarHBondContact O-N 3.49Å; M277-R279 VanDerWaalsContact C-N 3.34Å; M277-R279 PolarHBondContact O-N 3Å; M277-L280 PolarHBondContact O-N 3.31Å; M277-S281 PolarHBondContact O-N 3.45Å; M277-S281 PolarHBondContact O-OG 3.39Å
278	I	95.9	Very high	93.8	Very high	1 Å²	1	45.7 Å²	45.7	1%	0.005	24%	0.24	C	C	.	.	H	α-helix	trans	-61.2	-40.6	176.3	-64.1	-179.5	0	0	0	111.6	L140 S201 T204 F213 W274 W276 L280 S281 I282	L140-I278 HydrophobicContact CD1-CG1 4.16Å; L140-I278 HydrophobicContact CD2-CD1 4.12Å; L140-I278 HydrophobicContact CD2-CG1 3.97Å; S201-I278 WeakPolarHBondContact O-CG2 3.41Å; T204-I278 HydrophobicContact CG2-CD1 4.09Å; F213-I278 HydrophobicContact CE2-CD1 4.47Å; W274-I278 HydrophobicContact CE3-CD1 3.62Å; W274-I278 HydrophobicContact CE3-CG1 4.43Å; W274-I278 HydrophobicContact CZ3-CD1 3.71Å; W274-I278 PolarHBondContact O-N 2.77Å; W274-I278 VanDerWaalsContact O-N 3.09Å; W276-I278 VanDerWaalsContact C-N 3.34Å; W276-I278 PolarHBondContact O-N 3.23Å; I278-L280 VanDerWaalsContact C-N 3.34Å; I278-L280 PolarHBondContact O-N 3.04Å; I278-S281 WeakPolarHBondContact CA-OG 3.28Å; I278-S281 PolarHBondContact O-N 3.12Å; I278-S281 PolarHBondContact O-OG 2.87Å; I278-I282 HydrophobicContact CG2-CD1 4.29Å; I278-I282 WeakPolarHBondContact O-CD1 3.18Å; I278-I282 VanDerWaalsContact O-CG1 3.31Å; I278-I282 WeakPolarHBondContact O-CG1 3.09Å
279	R	96	Very high	93.5	Very high	58 Å²	58	47 Å²	47	22%	0.219	25%	0.247	C	C	.	.	H	α-helix	trans	-62.6	-42.4	177.8	-67.2	171.8	-166.7	154.1	7.6	111.7	L202 S205 R275 W276 M277	L202-R279 HydrophobicContact CD1-CG 4.18Å; S205-R279 PolarHBondContact O-NH2 3.25Å; S205-R279 VanDerWaalsContact OG-CG 3.32Å; S205-R279 WeakPolarHBondContact OG-CG 3.49Å; S205-R279 PolarHBondContact OG-NE 3.28Å; S205-R279 VanDerWaalsContact OG-NE 3.15Å; R275-R279 WeakPolarHBondContact O-CG 3.39Å; R275-R279 PolarHBondContact O-N 3.06Å; W276-R279 VanDerWaalsContact CE2-NH1 3.34Å; W276-R279 HydrophobicContact CE3-CB 4.41Å; W276-R279 PolarHBondContact O-N 3.34Å; M277-R279 VanDerWaalsContact C-N 3.34Å; M277-R279 PolarHBondContact O-N 3Å
280	L	95.9	Very high	93.4	Very high	65 Å²	65	53.6 Å²	53.6	34%	0.34	28%	0.275	S	S	.	.	H	α-helix	trans	-72.1	-34.5	179.9	-67.1	172.3	0	0	0	112.4	L264 V268 M272 W276 M277 I278 I282 T283	L264-L280 HydrophobicContact CD2-CB 4.33Å; V268-L280 HydrophobicContact CG1-CD1 4.17Å; V268-L280 HydrophobicContact CG2-CD1 3.72Å; M272-L280 HydrophobicContact CE-CD1 4.45Å; W276-L280 WeakPolarHBondContact O-CG 3.5Å; W276-L280 PolarHBondContact O-N 3.42Å; M277-L280 PolarHBondContact O-N 3.31Å; I278-L280 VanDerWaalsContact C-N 3.34Å; I278-L280 PolarHBondContact O-N 3.04Å; L280-I282 PolarHBondContact O-N 3.08Å; L280-I282 VanDerWaalsContact O-N 3.15Å; L280-T283 WeakPolarHBondContact O-CB 3.43Å; L280-T283 PolarHBondContact O-N 3.2Å; L280-T283 VanDerWaalsContact O-N 3.14Å; L280-T283 PolarHBondContact O-OG1 3.25Å
281	S	94.9	Very high	93.4	Very high	1 Å²	1	51.9 Å²	51.9	1%	0.007	26%	0.26	C	S	.	.	H	α-helix	trans	-64.9	-15.8	178.5	62.4	0	0	0	0	114.3	M277 I278 P284	M277-S281 PolarHBondContact O-N 3.45Å; M277-S281 PolarHBondContact O-OG 3.39Å; I278-S281 WeakPolarHBondContact CA-OG 3.28Å; I278-S281 PolarHBondContact O-N 3.12Å; I278-S281 PolarHBondContact O-OG 2.87Å; S281-P284 WeakPolarHBondContact O-CD 3.34Å
282	I	94.8	Very high	93.2	Very high	4 Å²	4	46.8 Å²	46.8	2%	0.021	23%	0.229	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.2	-14.9	178.7	-61.6	154.2	0	0	0	112.1	A198 L202 I278 L280 S285 I286	A198-I282 HydrophobicContact CB-CG2 3.97Å; L202-I282 HydrophobicContact CB-CD1 3.77Å; L202-I282 HydrophobicContact CD1-CD1 4.06Å; I278-I282 HydrophobicContact CG2-CD1 4.29Å; I278-I282 WeakPolarHBondContact O-CD1 3.18Å; I278-I282 VanDerWaalsContact O-CG1 3.31Å; I278-I282 WeakPolarHBondContact O-CG1 3.09Å; L280-I282 PolarHBondContact O-N 3.08Å; L280-I282 VanDerWaalsContact O-N 3.15Å; I282-S285 WeakPolarHBondContact O-CA 3.22Å; I282-S285 VanDerWaalsContact O-CB 3.23Å; I282-S285 WeakPolarHBondContact O-CB 3.09Å; I282-S285 PolarHBondContact O-N 2.92Å; I282-I286 HydrophobicContact CG2-CD1 4.03Å; I282-I286 HydrophobicContact CG2-CG1 4.06Å; I282-I286 PolarHBondContact O-N 3.32Å
283	T	93.3	Very high	92.9	Very high	70 Å²	70	50.3 Å²	50.3	43%	0.429	24%	0.242	S	C	.	.	H	α-helix	trans	-54	-46.1	-179.2	-45	0	0	0	0	113.2	L280 S285 I286 I287	L280-T283 WeakPolarHBondContact O-CB 3.43Å; L280-T283 PolarHBondContact O-N 3.2Å; L280-T283 VanDerWaalsContact O-N 3.14Å; L280-T283 PolarHBondContact O-OG1 3.25Å; T283-S285 VanDerWaalsContact C-N 3.31Å; T283-S285 PolarHBondContact O-N 3.19Å; T283-I286 PolarHBondContact O-N 3.14Å; T283-I287 HydrophobicContact CG2-CD1 4.34Å; T283-I287 WeakPolarHBondContact O-CG1 3.4Å; T283-I287 PolarHBondContact O-N 3.18Å; T283-I287 VanDerWaalsContact O-N 3.15Å
284	P	92.9	Very high	92.6	Very high	36 Å²	36	54.3 Å²	54.3	23%	0.234	25%	0.253	C	S	.	.	H	α-helix	trans	-64.4	-33.9	176.2	-19.8	34.5	0	0	0	112.9	V133 M136 L260 S281 I287 L288	V133-P284 HydrophobicContact CG2-CB 3.86Å; M136-P284 HydrophobicContact CE-CG 4.39Å; M136-P284 HydrophobicContact SD-CG 4.22Å; L260-P284 HydrophobicContact CD2-CG 4.35Å; S281-P284 WeakPolarHBondContact O-CD 3.34Å; P284-I287 PolarHBondContact O-N 3.45Å; P284-L288 WeakPolarHBondContact O-CB 3.45Å; P284-L288 WeakPolarHBondContact O-CG 3.38Å; P284-L288 PolarHBondContact O-N 2.74Å
285	S	91.9	Very high	92.4	Very high	2 Å²	2	54.3 Å²	54.3	1%	0.014	25%	0.254	C	S	.	.	H	α-helix	trans	-63.7	-42.2	176.2	-42.8	0	0	0	0	111.8	V133 I282 T283 L288 I289	V133-S285 WeakPolarHBondContact CG1-OG 3.47Å; I282-S285 WeakPolarHBondContact O-CA 3.22Å; I282-S285 VanDerWaalsContact O-CB 3.23Å; I282-S285 WeakPolarHBondContact O-CB 3.09Å; I282-S285 PolarHBondContact O-N 2.92Å; T283-S285 VanDerWaalsContact C-N 3.31Å; T283-S285 PolarHBondContact O-N 3.19Å; S285-L288 PolarHBondContact O-N 3.44Å; S285-I289 VanDerWaalsContact O-CG1 3.32Å; S285-I289 WeakPolarHBondContact O-CG1 3.4Å; S285-I289 PolarHBondContact O-N 2.95Å; S285-I289 VanDerWaalsContact O-N 3.08Å
286	I	91.4	Very high	92.2	Very high	87 Å²	87	51.7 Å²	51.7	45%	0.446	25%	0.246	S	C	.	.	H	α-helix	trans	-64.3	-45.7	176.3	-66.1	167.9	0	0	0	110.6	I282 T283 L288 I289 F290	I282-I286 HydrophobicContact CG2-CD1 4.03Å; I282-I286 HydrophobicContact CG2-CG1 4.06Å; I282-I286 PolarHBondContact O-N 3.32Å; T283-I286 PolarHBondContact O-N 3.14Å; I286-L288 VanDerWaalsContact C-N 3.32Å; I286-L288 PolarHBondContact O-N 3.25Å; I286-I289 PolarHBondContact O-N 3.03Å; I286-F290 HydrophobicContact CG2-CD2 4.47Å; I286-F290 HydrophobicContact CG2-CE2 3.89Å; I286-F290 WeakPolarHBondContact O-CD2 3.5Å
287	I	92.7	Very high	91.9	Very high	94 Å²	94	47 Å²	47	48%	0.482	23%	0.229	S	C	.	.	H	α-helix	trans	-58.8	-45.2	176.7	-65.8	166	0	0	0	110.5	T283 P284 I289 F290 L291	T283-I287 HydrophobicContact CG2-CD1 4.34Å; T283-I287 WeakPolarHBondContact O-CG1 3.4Å; T283-I287 PolarHBondContact O-N 3.18Å; T283-I287 VanDerWaalsContact O-N 3.15Å; P284-I287 PolarHBondContact O-N 3.45Å; I287-I289 PolarHBondContact O-N 2.96Å; I287-F290 PolarHBondContact O-N 3.12Å; I287-L291 HydrophobicContact CG2-CD1 4.04Å; I287-L291 HydrophobicContact CG2-CG 4.47Å; I287-L291 WeakPolarHBondContact O-CG 3.29Å; I287-L291 PolarHBondContact O-N 3.45Å
288	L	90.4	Very high	91.6	Very high	4 Å²	4	47 Å²	47	2%	0.021	23%	0.229	C	C	.	.	H	α-helix	trans	-59.7	-42.5	177.8	-83.6	173.4	0	0	0	113.3	I126 S129 A130 V133 Y194 P284 S285 I286 F290 L291 F292	I126-L288 HydrophobicContact CG2-CD2 4.1Å; I126-L288 WeakPolarHBondContact O-CD2 3.28Å; S129-L288 WeakPolarHBondContact OG-CD2 3.3Å; A130-L288 HydrophobicContact CB-CD1 4.43Å; V133-L288 HydrophobicContact CB-CD1 4.24Å; V133-L288 HydrophobicContact CG2-CD1 3.67Å; Y194-L288 HydrophobicContact CD1-CD1 4.42Å; Y194-L288 HydrophobicContact CE1-CD1 3.73Å; P284-L288 WeakPolarHBondContact O-CB 3.45Å; P284-L288 WeakPolarHBondContact O-CG 3.38Å; P284-L288 PolarHBondContact O-N 2.74Å; S285-L288 PolarHBondContact O-N 3.44Å; I286-L288 VanDerWaalsContact C-N 3.32Å; I286-L288 PolarHBondContact O-N 3.25Å; L288-F290 PolarHBondContact O-N 3.34Å; L288-L291 CarbonylContact O-C 3.6Å; L288-L291 WeakPolarHBondContact O-CA 3.46Å; L288-L291 PolarHBondContact O-N 3.07Å; L288-F292 HydrophobicContact CB-CD2 4.48Å; L288-F292 HydrophobicContact CB-CE2 4.4Å; L288-F292 VanDerWaalsContact O-CD2 3.24Å; L288-F292 WeakPolarHBondContact O-CD2 3.44Å; L288-F292 PolarHBondContact O-N 3.11Å
289	I	90.8	Very high	91.1	Very high	38 Å²	38	47.2 Å²	47.2	20%	0.195	23%	0.231	C	C	.	.	H	α-helix	trans	-53.6	-39.1	178.6	-73.4	162.4	0	0	0	111	F191 V195 A198 S285 I286 I287	F191-I289 HydrophobicContact CE2-CG2 3.89Å; F191-I289 HydrophobicContact CZ-CG2 4.16Å; V195-I289 HydrophobicContact CG2-CD1 4Å; V195-I289 HydrophobicContact CG2-CG1 4.12Å; V195-I289 HydrophobicContact CG2-CG2 4.29Å; A198-I289 HydrophobicContact CB-CD1 4.27Å; S285-I289 VanDerWaalsContact O-CG1 3.32Å; S285-I289 WeakPolarHBondContact O-CG1 3.4Å; S285-I289 PolarHBondContact O-N 2.95Å; S285-I289 VanDerWaalsContact O-N 3.08Å; I286-I289 PolarHBondContact O-N 3.03Å; I287-I289 PolarHBondContact O-N 2.96Å
290	F	90.7	Very high	90.5	Very high	148 Å²	148	47.4 Å²	47.4	65%	0.649	23%	0.231	S	C	*	.	H	α-helix	trans	-72.3	-38.3	173.7	-64.2	-71.5	0	0	0	113.1	I286 I287 L288 F292 K293	I286-F290 HydrophobicContact CG2-CD2 4.47Å; I286-F290 HydrophobicContact CG2-CE2 3.89Å; I286-F290 WeakPolarHBondContact O-CD2 3.5Å; I287-F290 PolarHBondContact O-N 3.12Å; L288-F290 PolarHBondContact O-N 3.34Å; F290-F292 VanDerWaalsContact C-N 3.32Å; F290-F292 PolarHBondContact O-N 2.64Å; F290-K293 WeakPolarHBondContact O-CB 2.99Å; F290-K293 PolarHBondContact O-N 2.9Å
291	L	90.8	Very high	90	Very high	58 Å²	58	45.5 Å²	45.5	30%	0.304	22%	0.22	S	C	.	.	H	α-helix	trans	-68.5	-26.3	178.4	-65	177.3	0	0	0	113.5	I126 I287 L288 K293 F294	I126-L291 HydrophobicContact CD1-CB 4.28Å; I126-L291 HydrophobicContact CG1-CB 4.3Å; I126-L291 HydrophobicContact CG2-CB 3.95Å; I287-L291 HydrophobicContact CG2-CD1 4.04Å; I287-L291 HydrophobicContact CG2-CG 4.47Å; I287-L291 WeakPolarHBondContact O-CG 3.29Å; I287-L291 PolarHBondContact O-N 3.45Å; L288-L291 CarbonylContact O-C 3.6Å; L288-L291 WeakPolarHBondContact O-CA 3.46Å; L288-L291 PolarHBondContact O-N 3.07Å; L291-K293 PolarHBondContact O-N 2.82Å; L291-K293 VanDerWaalsContact O-N 3.08Å; L291-F294 HydrophobicContact CD2-CD2 4.24Å; L291-F294 HydrophobicContact CD2-CE2 4.15Å; L291-F294 WeakPolarHBondContact O-CB 3.41Å; L291-F294 WeakPolarHBondContact O-CD2 3Å; L291-F294 PolarHBondContact O-N 3.32Å
292	F	87	Confident	89.6	Confident	0 Å²	0	46.1 Å²	46.1	0%	0	22%	0.223	C	C	.	.	G	3₁₀ helix	trans	-58.2	-22.9	176.9	-95.9	-79	0	0	0	114	M127 W187 V190 F191 Y194 L288 F290 F294 I295	M127-F292 HydrophobicContact CE-CE1 3.45Å; M127-F292 VanDerWaalsContact CE-CE1 3.45Å; M127-F292 HydrophobicContact CE-CZ 3.37Å; M127-F292 HydrophobicContact SD-CE1 4.48Å; W187-F292 PolarHBondContact NE1-O 3.46Å; W187-F292 VanDerWaalsContact NE1-O 3.17Å; V190-F292 HydrophobicContact CB-CE1 4.47Å; V190-F292 HydrophobicContact CG1-CE1 3.6Å; V190-F292 HydrophobicContact CG1-CZ 3.59Å; F191-F292 HydrophobicContact CD2-CB 3.67Å; F191-F292 HydrophobicContact CD2-CG 4.06Å; F191-F292 HydrophobicContact CE2-CB 4.18Å; Y194-F292 HydrophobicContact CD1-CE2 4.36Å; Y194-F292 HydrophobicContact CD2-CD2 4.24Å; Y194-F292 AromaticContact CD2-CE2 3.27Å; Y194-F292 HydrophobicContact CD2-CE2 3.27Å; Y194-F292 AromaticContact CD2-CZ 3.47Å; Y194-F292 HydrophobicContact CD2-CZ 3.47Å; Y194-F292 VanDerWaalsContact CD2-CZ 3.47Å; Y194-F292 AromaticContact CE2-CE2 3.53Å; Y194-F292 HydrophobicContact CE2-CE2 3.53Å; Y194-F292 AromaticContact CE2-CZ 3.47Å; Y194-F292 HydrophobicContact CE2-CZ 3.47Å; Y194-F292 VanDerWaalsContact CE2-CZ 3.47Å; Y194-F292 HydrophobicContact CG-CD2 4.49Å; Y194-F292 AromaticContact CG-CE2 3.8Å; Y194-F292 HydrophobicContact CG-CE2 3.8Å; Y194-F292 HydrophobicContact CG-CZ 4.42Å; L288-F292 HydrophobicContact CB-CD2 4.48Å; L288-F292 HydrophobicContact CB-CE2 4.4Å; L288-F292 VanDerWaalsContact O-CD2 3.24Å; L288-F292 WeakPolarHBondContact O-CD2 3.44Å; L288-F292 PolarHBondContact O-N 3.11Å; F290-F292 VanDerWaalsContact C-N 3.32Å; F290-F292 PolarHBondContact O-N 2.64Å; F292-F294 PolarHBondContact O-N 2.94Å; F292-I295 HydrophobicContact CD1-CD1 4.09Å; F292-I295 HydrophobicContact CE1-CD1 4.14Å; F292-I295 PolarHBondContact O-N 2.94Å; F292-I295 VanDerWaalsContact O-N 3.11Å
293	K	86.7	Confident	89.2	Confident	171 Å²	171	47 Å²	47	74%	0.743	23%	0.229	S	C	*	.	G	3₁₀ helix	trans	-59.2	-25.3	172.7	-174.6	177.1	178.1	-179.9	0	113.3	F290 L291	F290-K293 WeakPolarHBondContact O-CB 2.99Å; F290-K293 PolarHBondContact O-N 2.9Å; L291-K293 PolarHBondContact O-N 2.82Å; L291-K293 VanDerWaalsContact O-N 3.08Å
294	F	86.9	Confident	88.6	Confident	105 Å²	105	47.7 Å²	47.7	46%	0.461	24%	0.236	S	C	.	.	G	3₁₀ helix	trans	-79.1	-20.8	178.1	-64.5	-70.8	0	0	0	113.3	L122 I126 L291 F292 R317	L122-F294 HydrophobicContact CD2-CB 4.32Å; I126-F294 HydrophobicContact CD1-CB 4.04Å; L291-F294 HydrophobicContact CD2-CD2 4.24Å; L291-F294 HydrophobicContact CD2-CE2 4.15Å; L291-F294 WeakPolarHBondContact O-CB 3.41Å; L291-F294 WeakPolarHBondContact O-CD2 3Å; L291-F294 PolarHBondContact O-N 3.32Å; F292-F294 PolarHBondContact O-N 2.94Å; F294-R317 PolarHBondContact O-NH2 3.2Å
295	I	90.4	Very high	88.1	Confident	6 Å²	6	47.9 Å²	47.9	3%	0.031	24%	0.241	C	C	.	.	S	Bend	trans	-87.9	122.2	179.1	-56.7	175.7	0	0	0	108.9	L123 I126 M127 W187 F237 F292	L123-I295 HydrophobicContact CD1-CD1 4.23Å; L123-I295 HydrophobicContact CD1-CG1 4.19Å; L123-I295 HydrophobicContact CD1-CG2 3.94Å; I126-I295 HydrophobicContact CB-CD1 4.1Å; I126-I295 HydrophobicContact CD1-CG1 4.47Å; I126-I295 HydrophobicContact CG2-CD1 3.63Å; I126-I295 HydrophobicContact CG2-CG1 4.35Å; M127-I295 HydrophobicContact CE-CD1 4.14Å; M127-I295 HydrophobicContact CG-CD1 3.64Å; M127-I295 HydrophobicContact SD-CD1 3.83Å; W187-I295 PolarHBondContact NE1-O 3.33Å; F237-I295 HydrophobicContact CE2-CG2 4.43Å; F292-I295 HydrophobicContact CD1-CD1 4.09Å; F292-I295 HydrophobicContact CE1-CD1 4.14Å; F292-I295 PolarHBondContact O-N 2.94Å; F292-I295 VanDerWaalsContact O-N 3.11Å
296	P	90.9	Very high	87.7	Confident	13 Å²	13	50.8 Å²	50.8	8%	0.084	27%	0.271	C	S	.	.	P	Polyproline II helix	trans	-78.7	166.4	171.2	33.7	-34.3	0	0	0	111.7	F119 F237 T314	F119-P296 HydrophobicContact CE2-CG 4.14Å; F119-P296 HydrophobicContact CZ-CG 4.02Å; F237-P296 HydrophobicContact CE1-CG 4.2Å; F237-P296 HydrophobicContact CZ-CG 4.1Å; F237-P296 WeakPolarHBondContact CZ-O 3.43Å; P296-T314 HydrophobicContact CB-CG2 3.96Å; P296-T314 HydrophobicContact CG-CG2 3.84Å
297	E	90.5	Very high	87.5	Confident	26 Å²	26	52.2 Å²	52.2	12%	0.121	27%	0.274	C	S	.	.	P	Polyproline II helix	trans	-67.7	148.3	166.2	-173.7	63.5	-88.2	0	0	110.8	G185 R186 W187 Y301	G185-E297 VanDerWaalsContact C-OE2 3.3Å; G185-E297 WeakPolarHBondContact CA-OE2 3.35Å; R186-E297 PolarHBondContact N-OE1 3.23Å; W187-E297 HydrophobicContact CB-CB 4.38Å; W187-E297 WeakPolarHBondContact CB-OE1 3.42Å; W187-E297 WeakPolarHBondContact CB-OE2 3.32Å; W187-E297 PolarHBondContact N-OE1 2.94Å; W187-E297 PolarHBondContact N-OE2 3.48Å; E297-Y301 HydrophobicContact CG-CD1 3.51Å; E297-Y301 HydrophobicContact CG-CE1 4.14Å; E297-Y301 HydrophobicContact CG-CG 4.36Å
298	S	87.9	Confident	87.3	Confident	1 Å²	1	50.1 Å²	50.1	1%	0.007	27%	0.266	C	S	.	.	P	Polyproline II helix	trans	-58.8	139.4	-176.3	173.1	0	0	0	0	113.5	E236 R300 Y301 N302	E236-S298 WeakPolarHBondContact OE2-CB 3.14Å; E236-S298 PolarHBondContact OE2-OG 3.03Å; S298-R300 VanDerWaalsContact C-N 3.33Å; S298-R300 PolarHBondContact OG-N 3.11Å; S298-Y301 PolarHBondContact O-N 3.18Å; S298-N302 PolarHBondContact O-N 3.43Å; S298-N302 PolarHBondContact O-ND2 2.8Å
299	A	86.3	Confident	87.2	Confident	4 Å²	4	56 Å²	56	3%	0.033	30%	0.297	C	S	.	.	H	α-helix	trans	-62.7	-39.7	172.8	0	0	0	0	0	111.8	V107 N302 V303 A311 L315	V107-A299 HydrophobicContact CG1-CB 3.78Å; A299-N302 PolarHBondContact O-N 3.13Å; A299-V303 WeakPolarHBondContact O-CG2 3.49Å; A299-V303 PolarHBondContact O-N 3.08Å; A299-A311 HydrophobicContact CB-CB 4.31Å; A299-A311 WeakPolarHBondContact O-CB 3.34Å; A299-L315 HydrophobicContact CB-CD1 4.31Å; A299-L315 HydrophobicContact CB-CD2 3.83Å; A299-L315 HydrophobicContact CB-CG 3.85Å
300	R	84	Confident	87.1	Confident	63 Å²	63	55.8 Å²	55.8	24%	0.238	30%	0.301	C	S	.	.	H	α-helix	trans	-61.9	-45.9	177.3	-63.5	-177.9	-178.8	-145.7	-10.1	111.1	V107 E108 S298 V303 S304	V107-R300 HydrophobicContact CB-CG 4.26Å; V107-R300 HydrophobicContact CG1-CG 3.66Å; E108-R300 IonicContact OE1-CZ 3.52Å; E108-R300 IonicContact OE1-NH1 3.49Å; E108-R300 IonicContact OE1-NH2 2.71Å; E108-R300 PolarHBondContact OE1-NH2 3.19Å; S298-R300 VanDerWaalsContact C-N 3.33Å; S298-R300 PolarHBondContact OG-N 3.11Å; R300-V303 PolarHBondContact O-N 3.26Å; R300-S304 WeakPolarHBondContact O-CB 3.49Å; R300-S304 PolarHBondContact O-N 3.43Å; R300-S304 PolarHBondContact O-OG 3.2Å
301	Y	84.4	Confident	87.1	Confident	25 Å²	25	48.8 Å²	48.8	10%	0.098	27%	0.27	C	S	.	.	H	α-helix	trans	-58.1	-51	173.4	171.9	-99	0	0	0	111.1	R183 Y184 G185 E297 S298 V303 S304 A305	R183-Y301 PolarHBondContact O-OH 3.31Å; R183-Y301 VanDerWaalsContact O-OH 3.07Å; Y184-Y301 PolarHBondContact O-OH 3.35Å; G185-Y301 VanDerWaalsContact CA-CZ 3.43Å; G185-Y301 VanDerWaalsContact N-CZ 3.33Å; G185-Y301 PolarHBondContact N-OH 3.17Å; E297-Y301 HydrophobicContact CG-CD1 3.51Å; E297-Y301 HydrophobicContact CG-CE1 4.14Å; E297-Y301 HydrophobicContact CG-CG 4.36Å; S298-Y301 PolarHBondContact O-N 3.18Å; Y301-V303 PolarHBondContact O-N 3.37Å; Y301-S304 PolarHBondContact O-N 2.81Å; Y301-S304 VanDerWaalsContact O-N 3.14Å; Y301-S304 PolarHBondContact O-OG 2.72Å; Y301-A305 HydrophobicContact CE1-CB 4.17Å; Y301-A305 HydrophobicContact CE2-CB 4.34Å; Y301-A305 WeakPolarHBondContact O-CB 3.3Å; Y301-A305 PolarHBondContact O-N 2.8Å
302	N	86.9	Confident	87.1	Confident	14 Å²	14	47.8 Å²	47.8	8%	0.075	27%	0.267	C	S	.	.	H	α-helix	trans	-59.4	-41.4	-177	-78.4	-48.2	0	0	0	112.9	S298 A299 A305 G306 K307 A310 A311	S298-N302 PolarHBondContact O-N 3.43Å; S298-N302 PolarHBondContact O-ND2 2.8Å; A299-N302 PolarHBondContact O-N 3.13Å; N302-A305 PolarHBondContact O-N 2.83Å; N302-G306 PolarHBondContact O-N 2.9Å; N302-K307 CarbonylContact O-C 3.39Å; N302-K307 WeakPolarHBondContact O-CA 3.47Å; N302-K307 WeakPolarHBondContact O-CB 3.33Å; N302-K307 PolarHBondContact O-N 3.08Å; N302-A310 HydrophobicContact CB-CB 4.35Å; N302-A311 HydrophobicContact CB-CB 3.8Å
303	V	85.9	Confident	87.4	Confident	22 Å²	22	54.6 Å²	54.6	13%	0.133	30%	0.297	C	S	.	.	H	α-helix	trans	-65.5	-47.3	173.7	-179.6	0	0	0	0	111.1	V107 A299 R300 Y301 A305 G306 A311 L331 E333	V107-V303 HydrophobicContact CG2-CB 4.47Å; V107-V303 HydrophobicContact CG2-CG2 3.74Å; A299-V303 WeakPolarHBondContact O-CG2 3.49Å; A299-V303 PolarHBondContact O-N 3.08Å; R300-V303 PolarHBondContact O-N 3.26Å; Y301-V303 PolarHBondContact O-N 3.37Å; V303-A305 PolarHBondContact O-N 3.46Å; V303-A305 VanDerWaalsContact O-N 3.17Å; V303-G306 WeakPolarHBondContact O-CA 3.16Å; V303-G306 PolarHBondContact O-N 3.07Å; V303-A311 HydrophobicContact CG2-CB 3.46Å; V303-A311 VanDerWaalsContact CG2-CB 3.46Å; V303-L331 HydrophobicContact CG2-CD2 3.68Å; V303-L331 HydrophobicContact CG2-CG 4.3Å; V303-E333 VanDerWaalsContact CB-OE2 3.28Å; V303-E333 WeakPolarHBondContact CB-OE2 3.26Å; V303-E333 HydrophobicContact CG1-CB 3.72Å; V303-E333 VanDerWaalsContact CG1-OE2 3.26Å; V303-E333 WeakPolarHBondContact CG1-OE2 3.44Å
304	S	80.3	Confident	87.7	Confident	85 Å²	85	47.2 Å²	47.2	59%	0.594	27%	0.266	S	S	*	.	H	α-helix	trans	-62.1	-24.3	178.9	75.7	0	0	0	0	114	R300 Y301 G306	R300-S304 WeakPolarHBondContact O-CB 3.49Å; R300-S304 PolarHBondContact O-N 3.43Å; R300-S304 PolarHBondContact O-OG 3.2Å; Y301-S304 PolarHBondContact O-N 2.81Å; Y301-S304 VanDerWaalsContact O-N 3.14Å; Y301-S304 PolarHBondContact O-OG 2.72Å; S304-G306 VanDerWaalsContact C-N 3.31Å
305	A	83.1	Confident	87.9	Confident	40 Å²	40	42.2 Å²	42.2	33%	0.331	24%	0.244	S	C	.	.	T	Hydrogen-bonded Turn	trans	-88.2	8.8	174	0	0	0	0	0	113.6	Y301 N302 V303 K307	Y301-A305 HydrophobicContact CE1-CB 4.17Å; Y301-A305 HydrophobicContact CE2-CB 4.34Å; Y301-A305 WeakPolarHBondContact O-CB 3.3Å; Y301-A305 PolarHBondContact O-N 2.8Å; N302-A305 PolarHBondContact O-N 2.83Å; V303-A305 PolarHBondContact O-N 3.46Å; V303-A305 VanDerWaalsContact O-N 3.17Å; A305-K307 VanDerWaalsContact C-N 3.28Å; A305-K307 PolarHBondContact O-N 2.84Å
306	G	83.3	Confident	88	Confident	63 Å²	63	45.5 Å²	45.5	65%	0.649	26%	0.259	S	S	*	.	T	Hydrogen-bonded Turn	trans	76.2	5.3	-179.4	0	0	0	0	0	115.2	N302 V303 S304 V308	N302-G306 PolarHBondContact O-N 2.9Å; V303-G306 WeakPolarHBondContact O-CA 3.16Å; V303-G306 PolarHBondContact O-N 3.07Å; S304-G306 VanDerWaalsContact C-N 3.31Å; G306-V308 PolarHBondContact O-N 3.44Å
307	K	86.9	Confident	88.1	Confident	116 Å²	116	49.4 Å²	49.4	50%	0.504	27%	0.272	S	S	.	.			trans	-98.5	58.9	-173.1	-63	175.6	-176.8	175.3	0	111.5	N302 A305 D309 A310 A311	N302-K307 CarbonylContact O-C 3.39Å; N302-K307 WeakPolarHBondContact O-CA 3.47Å; N302-K307 WeakPolarHBondContact O-CB 3.33Å; N302-K307 PolarHBondContact O-N 3.08Å; A305-K307 VanDerWaalsContact C-N 3.28Å; A305-K307 PolarHBondContact O-N 2.84Å; K307-D309 VanDerWaalsContact C-N 3.28Å; K307-D309 PolarHBondContact O-N 3.5Å; K307-A310 HydrophobicContact CB-CB 4.09Å; K307-A310 WeakPolarHBondContact O-CB 3.26Å; K307-A310 PolarHBondContact O-N 3.17Å; K307-A311 PolarHBondContact O-N 3.31Å; K307-A311 VanDerWaalsContact O-N 3.17Å
308	V	88.1	Confident	88.2	Confident	51 Å²	51	48.4 Å²	48.4	31%	0.309	27%	0.268	S	S	.	.	H	α-helix	trans	-55	-41.8	-175.6	-174.1	0	0	0	0	111.9	G306 A310 A311 V312 L331	G306-V308 PolarHBondContact O-N 3.44Å; V308-A310 VanDerWaalsContact C-N 3.29Å; V308-A310 PolarHBondContact O-N 3.45Å; V308-A311 WeakPolarHBondContact O-CB 3.31Å; V308-A311 PolarHBondContact O-N 3.36Å; V308-A311 VanDerWaalsContact O-N 3.1Å; V308-V312 HydrophobicContact CG1-CG2 4.44Å; V308-V312 WeakPolarHBondContact O-CG2 3.48Å; V308-V312 PolarHBondContact O-N 3.39Å; V308-L331 HydrophobicContact CG1-CB 4.31Å; V308-L331 HydrophobicContact CG1-CD2 4.19Å; V308-L331 HydrophobicContact CG1-CG 4.4Å
309	D	89	Confident	88.4	Confident	126 Å²	126	48.6 Å²	48.6	67%	0.674	27%	0.269	S	S	*	.	H	α-helix	trans	-61.8	-34.5	178.4	-57.6	-35.4	0	0	0	113.3	K307 K313	K307-D309 VanDerWaalsContact C-N 3.28Å; K307-D309 PolarHBondContact O-N 3.5Å; D309-K313 WeakPolarHBondContact O-CB 3.24Å; D309-K313 VanDerWaalsContact O-CG 3.25Å; D309-K313 WeakPolarHBondContact O-CG 3.31Å; D309-K313 PolarHBondContact O-N 3.26Å
310	A	89.8	Confident	88.7	Confident	35 Å²	35	56.9 Å²	56.9	29%	0.289	30%	0.299	S	S	.	.	H	α-helix	trans	-72.6	-35.4	176.5	0	0	0	0	0	111.5	N302 K307 V308 T314	N302-A310 HydrophobicContact CB-CB 4.35Å; K307-A310 HydrophobicContact CB-CB 4.09Å; K307-A310 WeakPolarHBondContact O-CB 3.26Å; K307-A310 PolarHBondContact O-N 3.17Å; V308-A310 VanDerWaalsContact C-N 3.29Å; V308-A310 PolarHBondContact O-N 3.45Å; A310-T314 WeakPolarHBondContact O-CB 3.22Å; A310-T314 PolarHBondContact O-N 2.91Å; A310-T314 PolarHBondContact O-OG1 2.71Å
311	A	89.8	Confident	89.1	Confident	0 Å²	0	56.7 Å²	56.7	0%	0	30%	0.302	C	S	.	.	H	α-helix	trans	-64.4	-47.9	172.6	0	0	0	0	0	111.3	A299 N302 V303 K307 V308 K313 T314 L315 L331	A299-A311 HydrophobicContact CB-CB 4.31Å; A299-A311 WeakPolarHBondContact O-CB 3.34Å; N302-A311 HydrophobicContact CB-CB 3.8Å; V303-A311 HydrophobicContact CG2-CB 3.46Å; V303-A311 VanDerWaalsContact CG2-CB 3.46Å; K307-A311 PolarHBondContact O-N 3.31Å; K307-A311 VanDerWaalsContact O-N 3.17Å; V308-A311 WeakPolarHBondContact O-CB 3.31Å; V308-A311 PolarHBondContact O-N 3.36Å; V308-A311 VanDerWaalsContact O-N 3.1Å; A311-K313 PolarHBondContact O-N 2.68Å; A311-T314 WeakPolarHBondContact O-CB 3.04Å; A311-T314 PolarHBondContact O-N 3.44Å; A311-T314 VanDerWaalsContact O-N 3.15Å; A311-L315 WeakPolarHBondContact O-CG 3.28Å; A311-L315 PolarHBondContact O-N 3.5Å; A311-L331 HydrophobicContact CB-CD2 3.84Å
312	V	91.4	Very high	89.6	Confident	38 Å²	38	56.7 Å²	56.7	23%	0.23	30%	0.304	C	S	.	.	H	α-helix	trans	-60.6	-45.5	176.6	175.1	0	0	0	0	111.2	V308 T314 L315 Q316 L331	V308-V312 HydrophobicContact CG1-CG2 4.44Å; V308-V312 WeakPolarHBondContact O-CG2 3.48Å; V308-V312 PolarHBondContact O-N 3.39Å; V312-T314 VanDerWaalsContact C-N 3.29Å; V312-T314 PolarHBondContact O-N 2.9Å; V312-L315 PolarHBondContact O-N 3.25Å; V312-Q316 HydrophobicContact CG1-CG 4.3Å; V312-Q316 WeakPolarHBondContact O-CB 3.02Å; V312-Q316 VanDerWaalsContact O-CG 3.32Å; V312-Q316 WeakPolarHBondContact O-CG 3.22Å; V312-Q316 PolarHBondContact O-N 3.28Å; V312-L331 HydrophobicContact CG2-CB 3.95Å; V312-L331 HydrophobicContact CG2-CD2 3.77Å
313	K	93	Very high	89.8	Confident	143 Å²	143	65.5 Å²	65.5	62%	0.622	34%	0.336	S	S	*	.	H	α-helix	trans	-58.7	-38.9	174.7	-76.1	170.4	-177.3	174.6	0	112.6	D309 A311 R317	D309-K313 WeakPolarHBondContact O-CB 3.24Å; D309-K313 VanDerWaalsContact O-CG 3.25Å; D309-K313 WeakPolarHBondContact O-CG 3.31Å; D309-K313 PolarHBondContact O-N 3.26Å; A311-K313 PolarHBondContact O-N 2.68Å; K313-R317 PolarHBondContact O-N 2.71Å; K313-R317 VanDerWaalsContact O-N 3.08Å
314	T	92.2	Very high	90	Very high	15 Å²	15	66.1 Å²	66.1	9%	0.092	34%	0.343	C	S	.	.	H	α-helix	trans	-65.4	-50.4	175.5	-62.4	0	0	0	0	111.3	F237 P296 A310 A311 V312 Q316 R317 I318	F237-T314 HydrophobicContact CE1-CG2 4.31Å; P296-T314 HydrophobicContact CB-CG2 3.96Å; P296-T314 HydrophobicContact CG-CG2 3.84Å; A310-T314 WeakPolarHBondContact O-CB 3.22Å; A310-T314 PolarHBondContact O-N 2.91Å; A310-T314 PolarHBondContact O-OG1 2.71Å; A311-T314 WeakPolarHBondContact O-CB 3.04Å; A311-T314 PolarHBondContact O-N 3.44Å; A311-T314 VanDerWaalsContact O-N 3.15Å; V312-T314 VanDerWaalsContact C-N 3.29Å; V312-T314 PolarHBondContact O-N 2.9Å; T314-Q316 VanDerWaalsContact C-N 3.35Å; T314-Q316 PolarHBondContact O-N 3.39Å; T314-R317 WeakPolarHBondContact O-CB 3.47Å; T314-R317 PolarHBondContact O-N 3.22Å; T314-R317 VanDerWaalsContact O-N 3.1Å; T314-I318 HydrophobicContact CG2-CD1 4.06Å; T314-I318 WeakPolarHBondContact O-CG1 3.42Å; T314-I318 PolarHBondContact O-N 3.3Å
315	L	91.8	Very high	90.3	Very high	1 Å²	1	66.4 Å²	66.4	1%	0.005	35%	0.345	C	S	.	.	H	α-helix	trans	-62.6	-40.7	179	-64.7	168.2	0	0	0	111.7	A110 V111 I114 A299 A311 V312 R317 I318 A319 L326 L331	A110-L315 HydrophobicContact CB-CD1 3.9Å; A110-L315 HydrophobicContact CB-CD2 4.32Å; V111-L315 HydrophobicContact CG2-CD2 4.08Å; I114-L315 HydrophobicContact CD1-CB 4.34Å; I114-L315 HydrophobicContact CD1-CD2 4.43Å; A299-L315 HydrophobicContact CB-CD1 4.31Å; A299-L315 HydrophobicContact CB-CD2 3.83Å; A299-L315 HydrophobicContact CB-CG 3.85Å; A311-L315 WeakPolarHBondContact O-CG 3.28Å; A311-L315 PolarHBondContact O-N 3.5Å; V312-L315 PolarHBondContact O-N 3.25Å; L315-R317 VanDerWaalsContact C-N 3.31Å; L315-R317 PolarHBondContact O-N 3.31Å; L315-I318 PolarHBondContact O-N 2.96Å; L315-A319 VanDerWaalsContact O-CB 3.32Å; L315-A319 WeakPolarHBondContact O-CB 3.25Å; L315-A319 PolarHBondContact O-N 3.07Å; L315-L326 HydrophobicContact CB-CD2 3.92Å; L315-L326 HydrophobicContact CD1-CD2 4.5Å; L315-L331 HydrophobicContact CD1-CD2 4.2Å
316	Q	92.9	Very high	90.6	Very high	74 Å²	74	66.5 Å²	66.5	35%	0.346	34%	0.34	S	S	.	.	H	α-helix	trans	-59.2	-38.6	172.6	-76.3	-177.7	4.9	0	0	112.9	V312 T314 R320 L326	V312-Q316 HydrophobicContact CG1-CG 4.3Å; V312-Q316 WeakPolarHBondContact O-CB 3.02Å; V312-Q316 VanDerWaalsContact O-CG 3.32Å; V312-Q316 WeakPolarHBondContact O-CG 3.22Å; V312-Q316 PolarHBondContact O-N 3.28Å; T314-Q316 VanDerWaalsContact C-N 3.35Å; T314-Q316 PolarHBondContact O-N 3.39Å; Q316-R320 WeakPolarHBondContact O-CB 3.42Å; Q316-R320 VanDerWaalsContact O-CG 3.26Å; Q316-R320 WeakPolarHBondContact O-CG 3.47Å; Q316-R320 PolarHBondContact O-N 3.46Å; Q316-R320 PolarHBondContact O-NE 3.38Å; Q316-R320 VanDerWaalsContact OE1-NH2 3.08Å; Q316-L326 HydrophobicContact CB-CD1 4.39Å; Q316-L326 HydrophobicContact CG-CD1 3.47Å; Q316-L326 VanDerWaalsContact CG-CD1 3.47Å
317	R	92.3	Very high	90.7	Very high	96 Å²	96	64.5 Å²	64.5	36%	0.362	32%	0.315	S	S	.	.	H	α-helix	trans	-65.2	-43.2	176.3	-179.9	-179.7	174.6	-171.6	-3.9	111	F294 K313 T314 L315 M321	F294-R317 PolarHBondContact O-NH2 3.2Å; K313-R317 PolarHBondContact O-N 2.71Å; K313-R317 VanDerWaalsContact O-N 3.08Å; T314-R317 WeakPolarHBondContact O-CB 3.47Å; T314-R317 PolarHBondContact O-N 3.22Å; T314-R317 VanDerWaalsContact O-N 3.1Å; L315-R317 VanDerWaalsContact C-N 3.31Å; L315-R317 PolarHBondContact O-N 3.31Å; R317-M321 HydrophobicContact CG-SD 4.42Å; R317-M321 WeakPolarHBondContact O-CG 3.34Å; R317-M321 PolarHBondContact O-N 3.04Å
318	I	92.4	Very high	90.4	Very high	5 Å²	5	62.9 Å²	62.9	3%	0.026	32%	0.317	C	S	.	.	H	α-helix	trans	-65.6	-46.9	177.7	-60.3	168.8	0	0	0	110.3	I114 F119 F237 T314 L315 R320 M321 N322	I114-I318 HydrophobicContact CG2-CG2 3.85Å; F119-I318 HydrophobicContact CB-CG2 4.1Å; F119-I318 HydrophobicContact CD1-CB 4.27Å; F119-I318 HydrophobicContact CD1-CD1 4.18Å; F119-I318 HydrophobicContact CD1-CG1 3.8Å; F119-I318 HydrophobicContact CD1-CG2 3.59Å; F119-I318 HydrophobicContact CD2-CG1 4.22Å; F119-I318 HydrophobicContact CE1-CD1 3.74Å; F119-I318 HydrophobicContact CE1-CG1 3.74Å; F119-I318 HydrophobicContact CE1-CG2 4.25Å; F119-I318 HydrophobicContact CE2-CG1 4.17Å; F119-I318 HydrophobicContact CG-CB 4.39Å; F119-I318 HydrophobicContact CG-CG1 4.03Å; F119-I318 HydrophobicContact CG-CG2 3.94Å; F119-I318 HydrophobicContact CZ-CD1 4.08Å; F119-I318 HydrophobicContact CZ-CG1 3.94Å; F237-I318 HydrophobicContact CD1-CD1 3.8Å; F237-I318 HydrophobicContact CE1-CD1 3.91Å; T314-I318 HydrophobicContact CG2-CD1 4.06Å; T314-I318 WeakPolarHBondContact O-CG1 3.42Å; T314-I318 PolarHBondContact O-N 3.3Å; L315-I318 PolarHBondContact O-N 2.96Å; I318-R320 PolarHBondContact O-N 3.48Å; I318-M321 PolarHBondContact O-N 3.03Å; I318-N322 WeakPolarHBondContact O-CB 3.35Å; I318-N322 PolarHBondContact O-N 3.09Å
319	A	92.3	Very high	90.1	Very high	5 Å²	5	62.3 Å²	62.3	4%	0.041	32%	0.321	C	S	.	.	H	α-helix	trans	-55.3	-50.8	176.2	0	0	0	0	0	111.6	I114 L315 M321 N322 R323 A324	I114-A319 HydrophobicContact CD1-CB 3.92Å; I114-A319 HydrophobicContact CG1-CB 3.95Å; L315-A319 VanDerWaalsContact O-CB 3.32Å; L315-A319 WeakPolarHBondContact O-CB 3.25Å; L315-A319 PolarHBondContact O-N 3.07Å; A319-M321 PolarHBondContact O-N 3.18Å; A319-N322 CarbonylContact O-C 3.4Å; A319-N322 PolarHBondContact O-N 3.18Å; A319-R323 PolarHBondContact O-N 3.12Å; A319-A324 CarbonylContact C-O 3.54Å; A319-A324 WeakPolarHBondContact CB-O 3.34Å; A319-A324 PolarHBondContact O-N 3.22Å
320	R	93.3	Very high	89.9	Confident	177 Å²	177	65.1 Å²	65.1	67%	0.668	32%	0.322	S	S	*	.	H	α-helix	trans	-56.8	-44.2	174.7	-75.2	179.4	-120.9	177.8	-4.6	112.9	Q316 I318 R323	Q316-R320 WeakPolarHBondContact O-CB 3.42Å; Q316-R320 VanDerWaalsContact O-CG 3.26Å; Q316-R320 WeakPolarHBondContact O-CG 3.47Å; Q316-R320 PolarHBondContact O-N 3.46Å; Q316-R320 PolarHBondContact O-NE 3.38Å; Q316-R320 VanDerWaalsContact OE1-NH2 3.08Å; I318-R320 PolarHBondContact O-N 3.48Å; R320-R323 PolarHBondContact O-N 3.37Å
321	M	92.8	Very high	89.6	Confident	60 Å²	60	63.9 Å²	63.9	30%	0.296	31%	0.311	S	S	.	.	H	α-helix	trans	-67.7	-33.9	178.6	-74.4	-178.4	66.8	0	0	113	F119 L122 R317 I318 A319 R323	F119-M321 HydrophobicContact CB-CB 4.03Å; F119-M321 HydrophobicContact CB-CE 4.2Å; F119-M321 HydrophobicContact CB-SD 4.4Å; F119-M321 HydrophobicContact CD2-CE 4.06Å; F119-M321 HydrophobicContact CD2-SD 3.87Å; L122-M321 HydrophobicContact CD2-CE 3.92Å; R317-M321 HydrophobicContact CG-SD 4.42Å; R317-M321 WeakPolarHBondContact O-CG 3.34Å; R317-M321 PolarHBondContact O-N 3.04Å; I318-M321 PolarHBondContact O-N 3.03Å; A319-M321 PolarHBondContact O-N 3.18Å; M321-R323 VanDerWaalsContact C-N 3.34Å
322	N	93.2	Very high	89.2	Confident	24 Å²	24	66.9 Å²	66.9	13%	0.128	33%	0.329	C	S	.	.	H	α-helix	trans	-84.7	-6.2	177.2	-68.8	-4.6	0	0	0	113.4	I114 G115 G117 R118 F119 H120 I318 A319 A324	I114-N322 HydrophobicContact CG2-CB 4.24Å; I114-N322 WeakPolarHBondContact CG2-ND2 3.19Å; G115-N322 PolarHBondContact O-ND2 3.38Å; G117-N322 VanDerWaalsContact C-OD1 3.24Å; G117-N322 WeakPolarHBondContact CA-OD1 3.18Å; R118-N322 PolarHBondContact N-OD1 3.18Å; R118-N322 VanDerWaalsContact N-OD1 3.11Å; F119-N322 WeakPolarHBondContact CB-OD1 3.4Å; F119-N322 PolarHBondContact N-OD1 3.32Å; H120-N322 PolarHBondContact CE1-ND2 3.25Å; H120-N322 VanDerWaalsContact CE1-ND2 3.31Å; H120-N322 PolarHBondContact ND1-ND2 3Å; H120-N322 VanDerWaalsContact ND1-ND2 3.18Å; I318-N322 WeakPolarHBondContact O-CB 3.35Å; I318-N322 PolarHBondContact O-N 3.09Å; A319-N322 CarbonylContact O-C 3.4Å; A319-N322 PolarHBondContact O-N 3.18Å; N322-A324 VanDerWaalsContact C-N 3.25Å; N322-A324 HydrophobicContact CB-CB 4.45Å; N322-A324 PolarHBondContact O-N 3.38Å
323	R	91.1	Very high	88.5	Confident	200 Å²	200	67.9 Å²	67.9	76%	0.755	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	58.9	34.7	-170.9	-55.4	176.4	172.8	178.9	-7.4	113	A319 R320 M321	A319-R323 PolarHBondContact O-N 3.12Å; R320-R323 PolarHBondContact O-N 3.37Å; M321-R323 VanDerWaalsContact C-N 3.34Å
324	A	90.6	Very high	87.3	Confident	35 Å²	35	65.4 Å²	65.4	29%	0.289	33%	0.33	S	S	.	.			trans	-109.7	162.3	176.3	0	0	0	0	0	111	I114 A319 N322	I114-A324 HydrophobicContact CG2-CB 4.37Å; A319-A324 CarbonylContact C-O 3.54Å; A319-A324 WeakPolarHBondContact CB-O 3.34Å; A319-A324 PolarHBondContact O-N 3.22Å; N322-A324 VanDerWaalsContact C-N 3.25Å; N322-A324 HydrophobicContact CB-CB 4.45Å; N322-A324 PolarHBondContact O-N 3.38Å
325	S	87.7	Confident	85.7	Confident	91 Å²	91	69.2 Å²	69.2	64%	0.636	36%	0.362	S	S	*	.	P	Polyproline II helix	trans	-94.5	162.1	168.3	48.6	0	0	0	0	111.4
326	L	87.6	Confident	84	Confident	42 Å²	42	76.4 Å²	76.4	22%	0.22	40%	0.4	C	S	.	.	P	Polyproline II helix	trans	-78.6	156.6	164.1	-87.5	160.6	0	0	0	110.1	F105 A110 I114 L315 Q316	F105-L326 HydrophobicContact CE2-CD2 4.23Å; F105-L326 HydrophobicContact CZ-CD2 4.2Å; A110-L326 HydrophobicContact CB-CD2 4.05Å; I114-L326 HydrophobicContact CD1-CD2 4.07Å; L315-L326 HydrophobicContact CB-CD2 3.92Å; L315-L326 HydrophobicContact CD1-CD2 4.5Å; Q316-L326 HydrophobicContact CB-CD1 4.39Å; Q316-L326 HydrophobicContact CG-CD1 3.47Å; Q316-L326 VanDerWaalsContact CG-CD1 3.47Å
327	P	85.9	Confident	81.7	Confident	20 Å²	20	84 Å²	84	13%	0.13	43%	0.426	C	S	.	.	P	Polyproline II helix	trans	-55.9	148	163.4	-18.3	30.3	0	0	0	110.7	F105 A110 T113	F105-P327 HydrophobicContact CB-CB 4.02Å; F105-P327 HydrophobicContact CB-CG 4.31Å; F105-P327 HydrophobicContact CD1-CB 3.97Å; F105-P327 HydrophobicContact CD2-CG 4.24Å; F105-P327 WeakPolarHBondContact CE1-O 3.36Å; F105-P327 HydrophobicContact CG-CB 3.94Å; F105-P327 HydrophobicContact CG-CG 4.14Å; A110-P327 HydrophobicContact CB-CG 4.37Å; T113-P327 HydrophobicContact CG2-CG 4.18Å
328	P	80.4	Confident	79.9	Confident	82 Å²	82	87.1 Å²	87.1	53%	0.532	44%	0.444	S	S	.	.	S	Bend	trans	-65.5	155.7	168.9	32.3	-36.7	0	0	0	110.8	E103 F105	E103-P328 WeakPolarHBondContact OE2-CB 3.31Å; E103-P328 WeakPolarHBondContact OE2-CG 3.45Å; F105-P328 WeakPolarHBondContact CD1-O 3.38Å
329	G	83.6	Confident	78.3	Confident	39 Å²	39	96.6 Å²	96.6	40%	0.402	48%	0.48	S	S	.	.	S	Bend	trans	104.2	-164.2	177.6	0	0	0	0	0	116.1	E103 F105	E103-G329 CarbonylContact O-C 3.58Å; E103-G329 WeakPolarHBondContact O-CA 3.39Å; F105-G329 WeakPolarHBondContact CE1-O 3.17Å
330	R	83.6	Confident	76.8	Confident	185 Å²	185	97 Å²	97	70%	0.698	49%	0.485	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-105.7	135.7	-179.4	-173.5	174.8	-179.6	172.4	1.2	111.3	E103 K104 F105 V332	E103-R330 PolarHBondContact O-N 2.86Å; K104-R330 WeakPolarHBondContact CA-O 3.24Å; F105-R330 PolarHBondContact N-O 3.37Å; R330-V332 HydrophobicContact CG-CG2 4.22Å; R330-V332 PolarHBondContact O-N 3.22Å; R330-V332 VanDerWaalsContact O-N 3.11Å
331	L	84	Confident	76.1	Confident	9 Å²	9	91.2 Å²	91.2	5%	0.047	47%	0.471	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-65.1	110.8	171.6	-179.3	62.8	0	0	0	109.9	F105 V107 V303 V308 A311 V312 L315	F105-L331 HydrophobicContact CD2-CD1 3.9Å; F105-L331 HydrophobicContact CE2-CB 3.94Å; F105-L331 HydrophobicContact CE2-CD1 3.71Å; F105-L331 HydrophobicContact CE2-CG 4.38Å; F105-L331 HydrophobicContact CZ-CB 4.04Å; F105-L331 WeakPolarHBondContact O-CA 3.19Å; V107-L331 HydrophobicContact CG2-CD1 3.81Å; V107-L331 HydrophobicContact CG2-CD2 4.44Å; V303-L331 HydrophobicContact CG2-CD2 3.68Å; V303-L331 HydrophobicContact CG2-CG 4.3Å; V308-L331 HydrophobicContact CG1-CB 4.31Å; V308-L331 HydrophobicContact CG1-CD2 4.19Å; V308-L331 HydrophobicContact CG1-CG 4.4Å; A311-L331 HydrophobicContact CB-CD2 3.84Å; V312-L331 HydrophobicContact CG2-CB 3.95Å; V312-L331 HydrophobicContact CG2-CD2 3.77Å; L315-L331 HydrophobicContact CD1-CD2 4.2Å
332	V	82.1	Confident	75.5	Confident	63 Å²	63	95 Å²	95	38%	0.382	48%	0.482	S	S	.	.			trans	-134.4	116.9	175.4	179.8	0	0	0	0	107.7	K104 F105 R330	K104-V332 HydrophobicContact CB-CB 4.45Å; K104-V332 HydrophobicContact CD-CG2 4.39Å; K104-V332 HydrophobicContact CG-CB 4.45Å; K104-V332 HydrophobicContact CG-CG2 4.06Å; F105-V332 PolarHBondContact O-N 3.35Å; R330-V332 HydrophobicContact CG-CG2 4.22Å; R330-V332 PolarHBondContact O-N 3.22Å; R330-V332 VanDerWaalsContact O-N 3.11Å
333	E	76	Confident	75.2	Confident	60 Å²	60	102.4 Å²	102.4	28%	0.28	51%	0.508	S	S	.	.			trans	-97.1	126.8	175.3	-160.4	147.8	-140.8	0	0	108.1	V107 V303 A335	V107-E333 WeakPolarHBondContact CG2-OE2 3.36Å; V303-E333 VanDerWaalsContact CB-OE2 3.28Å; V303-E333 WeakPolarHBondContact CB-OE2 3.26Å; V303-E333 HydrophobicContact CG1-CB 3.72Å; V303-E333 VanDerWaalsContact CG1-OE2 3.26Å; V303-E333 WeakPolarHBondContact CG1-OE2 3.44Å; E333-A335 PolarHBondContact O-N 2.89Å
334	P	67.2	Low	74.9	Confident	91 Å²	91	95.6 Å²	95.6	59%	0.591	49%	0.486	S	S	*	.			trans	-59.5	136.2	179.8	24.5	-33.7	0	0	0	109.3	L336	P334-L336 PolarHBondContact O-N 2.87Å
335	A	58.7	Low	74.6	Confident	94 Å²	94	94 Å²	94	78%	0.777	47%	0.473	S	S	*	.			trans	-58.2	110	176.2	0	0	0	0	0	108.8	E333 R337	E333-A335 PolarHBondContact O-N 2.89Å; A335-R337 VanDerWaalsContact C-N 3.33Å; A335-R337 PolarHBondContact O-N 2.82Å
336	L	56.3	Low	74.8	Confident	152 Å²	152	94 Å²	94	80%	0.796	46%	0.461	S	S	*	.			trans	-58.7	95.9	177.2	-94.9	152.7	0	0	0	108.9	P334 E338	P334-L336 PolarHBondContact O-N 2.87Å; L336-E338 PolarHBondContact O-N 3.44Å
337	R	45	Very low	74.7	Confident	233 Å²	233	93.4 Å²	93.4	88%	0.879	46%	0.461	S	S	*	.	S	Bend	trans	-62.5	102.6	171.8	-91.4	-180	165.5	164.6	-4.7	107.6	A335	A335-R337 VanDerWaalsContact C-N 3.33Å; A335-R337 PolarHBondContact O-N 2.82Å
338	E	55	Low	74.8	Confident	162 Å²	162	98.5 Å²	98.5	76%	0.757	49%	0.494	S	S	*	.			trans	68	114.7	178.1	-52.3	-167	168	0	0	116.3	L336 G340	L336-E338 PolarHBondContact O-N 3.44Å; E338-G340 PolarHBondContact O-N 2.92Å
339	R	59	Low	75.1	Confident	205 Å²	205	99.8 Å²	99.8	77%	0.774	50%	0.501	S	S	*	.	P	Polyproline II helix	trans	-64.1	126.8	152.9	-68.3	-177.7	179.4	-166.2	-1.6	106.9	S341	R339-S341 PolarHBondContact O-N 3.42Å
340	G	59.9	Low	75.2	Confident	14 Å²	14	99.4 Å²	99.4	14%	0.144	49%	0.488	C	S	.	.	P	Polyproline II helix	trans	-53.1	137.3	-178.2	0	0	0	0	0	112.2	E338 I496 L500	E338-G340 PolarHBondContact O-N 2.92Å; G340-I496 VanDerWaalsContact N-CG2 3.35Å; G340-L500 WeakPolarHBondContact O-CD1 3.35Å
341	S	78.9	Confident	75.6	Confident	54 Å²	54	97.7 Å²	97.7	38%	0.378	48%	0.482	S	S	.	.	P	Polyproline II helix	trans	-71.3	141.6	169.3	-171.1	0	0	0	0	109.8	R339 R343 I344	R339-S341 PolarHBondContact O-N 3.42Å; S341-R343 PolarHBondContact O-N 2.59Å; S341-R343 WeakPolarHBondContact OG-CG 3.34Å; S341-R343 PolarHBondContact OG-N 2.87Å; S341-I344 WeakPolarHBondContact O-CB 3.5Å; S341-I344 VanDerWaalsContact O-CG1 3.27Å; S341-I344 WeakPolarHBondContact O-CG1 3.35Å; S341-I344 PolarHBondContact O-N 2.84Å
342	W	80.4	Confident	76	Confident	141 Å²	141	103.8 Å²	103.8	53%	0.534	50%	0.504	S	S	.	.	G	3₁₀ helix	trans	-56	-23.1	171.1	62.7	-95.9	0	0	0	112.5	I344 L345 F346 F504	W342-I344 PolarHBondContact O-N 2.72Å; W342-L345 WeakPolarHBondContact O-CB 3.47Å; W342-L345 PolarHBondContact O-N 3.21Å; W342-L345 VanDerWaalsContact O-N 3.11Å; W342-F346 AromaticContact CE3-CD2 3.8Å; W342-F346 HydrophobicContact CE3-CD2 3.8Å; W342-F346 AromaticContact CE3-CE2 3.67Å; W342-F346 HydrophobicContact CE3-CE2 3.67Å; W342-F346 AromaticContact CZ3-CD2 3.87Å; W342-F346 HydrophobicContact CZ3-CD2 3.87Å; W342-F346 AromaticContact CZ3-CE2 3.71Å; W342-F346 HydrophobicContact CZ3-CE2 3.71Å; W342-F504 HydrophobicContact CB-CE2 4.12Å; W342-F504 HydrophobicContact CB-CZ 4.31Å
343	R	85.4	Confident	76.5	Confident	179 Å²	179	100.9 Å²	100.9	68%	0.675	49%	0.486	S	S	*	.	G	3₁₀ helix	trans	-55.7	-27.4	171.7	-63.5	179.3	179.8	-179.7	0.1	113.3	S341 L345 F346 S347	S341-R343 PolarHBondContact O-N 2.59Å; S341-R343 WeakPolarHBondContact OG-CG 3.34Å; S341-R343 PolarHBondContact OG-N 2.87Å; R343-L345 PolarHBondContact O-N 3.42Å; R343-F346 CarbonylContact O-C 3.51Å; R343-F346 PolarHBondContact O-N 2.93Å; R343-S347 PolarHBondContact O-N 3.45Å; R343-S347 VanDerWaalsContact O-N 3.15Å
344	I	84.8	Confident	77.4	Confident	56 Å²	56	98 Å²	98	29%	0.287	47%	0.473	S	S	.	.	G	3₁₀ helix	trans	-59.1	-36.1	176.9	-62.7	169.4	0	0	0	111	S341 W342 F346 S347 F350 A497	S341-I344 WeakPolarHBondContact O-CB 3.5Å; S341-I344 VanDerWaalsContact O-CG1 3.27Å; S341-I344 WeakPolarHBondContact O-CG1 3.35Å; S341-I344 PolarHBondContact O-N 2.84Å; W342-I344 PolarHBondContact O-N 2.72Å; I344-F346 PolarHBondContact O-N 2.82Å; I344-S347 VanDerWaalsContact O-CB 3.27Å; I344-S347 WeakPolarHBondContact O-CB 3.36Å; I344-S347 PolarHBondContact O-N 3.33Å; I344-S347 PolarHBondContact O-OG 3.32Å; I344-F350 HydrophobicContact CG2-CD2 4.19Å; I344-F350 HydrophobicContact CG2-CE2 4.49Å; I344-A497 HydrophobicContact CG2-CB 4.14Å
345	L	86.2	Confident	78.7	Confident	2 Å²	2	97.7 Å²	97.7	1%	0.01	47%	0.466	C	S	.	.	G	3₁₀ helix	trans	-65.7	-24.1	178.2	-58	179.1	0	0	0	112.9	W342 R343 R351 S354 W358 Y493 L500 F504	W342-L345 WeakPolarHBondContact O-CB 3.47Å; W342-L345 PolarHBondContact O-N 3.21Å; W342-L345 VanDerWaalsContact O-N 3.11Å; R343-L345 PolarHBondContact O-N 3.42Å; L345-R351 WeakPolarHBondContact O-CA 3.38Å; L345-S354 WeakPolarHBondContact O-CB 3.39Å; L345-S354 PolarHBondContact O-OG 2.77Å; L345-W358 HydrophobicContact CB-CZ2 4.45Å; L345-Y493 HydrophobicContact CD2-CD1 4.13Å; L345-Y493 HydrophobicContact CD2-CE1 3.55Å; L345-L500 HydrophobicContact CD1-CB 4.38Å; L345-F504 HydrophobicContact CD1-CB 4.23Å; L345-F504 HydrophobicContact CD1-CD2 3.42Å; L345-F504 VanDerWaalsContact CD1-CD2 3.42Å; L345-F504 HydrophobicContact CD1-CE2 3.92Å; L345-F504 HydrophobicContact CD1-CG 3.89Å
346	F	89.9	Confident	80.4	Confident	90 Å²	90	95 Å²	95	40%	0.395	44%	0.438	S	S	.	.	G	3₁₀ helix	trans	-99.2	-2.4	178.1	-67.6	-88	0	0	0	113.7	W342 R343 I344 W358	W342-F346 AromaticContact CE3-CD2 3.8Å; W342-F346 HydrophobicContact CE3-CD2 3.8Å; W342-F346 AromaticContact CE3-CE2 3.67Å; W342-F346 HydrophobicContact CE3-CE2 3.67Å; W342-F346 AromaticContact CZ3-CD2 3.87Å; W342-F346 HydrophobicContact CZ3-CD2 3.87Å; W342-F346 AromaticContact CZ3-CE2 3.71Å; W342-F346 HydrophobicContact CZ3-CE2 3.71Å; R343-F346 CarbonylContact O-C 3.51Å; R343-F346 PolarHBondContact O-N 2.93Å; I344-F346 PolarHBondContact O-N 2.82Å; F346-W358 AromaticContact CE1-CH2 3.77Å; F346-W358 HydrophobicContact CE1-CH2 3.77Å; F346-W358 HydrophobicContact CE1-CZ3 4.14Å; F346-W358 HydrophobicContact CE2-CH2 4.01Å; F346-W358 AromaticContact CZ-CH2 3.5Å; F346-W358 HydrophobicContact CZ-CH2 3.5Å; F346-W358 HydrophobicContact CZ-CZ3 4.12Å
347	S	87.5	Confident	82.2	Confident	31 Å²	31	87.7 Å²	87.7	22%	0.217	40%	0.4	C	S	.	.	S	Bend	trans	-56.1	150.5	173.8	66.7	0	0	0	0	111.2	R343 I344 T349 F350 R351	R343-S347 PolarHBondContact O-N 3.45Å; R343-S347 VanDerWaalsContact O-N 3.15Å; I344-S347 VanDerWaalsContact O-CB 3.27Å; I344-S347 WeakPolarHBondContact O-CB 3.36Å; I344-S347 PolarHBondContact O-N 3.33Å; I344-S347 PolarHBondContact O-OG 3.32Å; S347-T349 PolarHBondContact O-N 3.42Å; S347-T349 VanDerWaalsContact O-N 3.1Å; S347-F350 PolarHBondContact O-N 2.92Å; S347-F350 PolarHBondContact OG-N 2.88Å; S347-R351 VanDerWaalsContact O-CB 3.23Å; S347-R351 WeakPolarHBondContact O-CB 3.38Å; S347-R351 PolarHBondContact O-N 3.23Å
348	P	86.3	Confident	84.6	Confident	127 Å²	127	77.5 Å²	77.5	83%	0.825	36%	0.361	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.3	-33.2	-179	21.3	-33	0	0	0	112.8
349	T	86.5	Confident	86.6	Confident	109 Å²	109	73.3 Å²	73.3	67%	0.669	34%	0.339	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.6	-42.4	176.7	-42.3	0	0	0	0	113.5	S347	S347-T349 PolarHBondContact O-N 3.42Å; S347-T349 VanDerWaalsContact O-N 3.1Å
350	F	87.6	Confident	88.4	Confident	31 Å²	31	63.6 Å²	63.6	14%	0.136	30%	0.302	C	S	.	.	T	Hydrogen-bonded Turn	trans	-105.5	-20.1	-173.9	-69.5	-69.9	0	0	0	114.5	I344 S347 R352 T353 S354 Y493 P494	I344-F350 HydrophobicContact CG2-CD2 4.19Å; I344-F350 HydrophobicContact CG2-CE2 4.49Å; S347-F350 PolarHBondContact O-N 2.92Å; S347-F350 PolarHBondContact OG-N 2.88Å; F350-R352 VanDerWaalsContact C-N 3.33Å; F350-R352 PolarHBondContact O-N 3.39Å; F350-R352 VanDerWaalsContact O-N 3.17Å; F350-T353 CarbonylContact O-C 3.45Å; F350-T353 WeakPolarHBondContact O-CA 3.4Å; F350-T353 WeakPolarHBondContact O-CB 3.29Å; F350-T353 PolarHBondContact O-N 3.23Å; F350-S354 PolarHBondContact O-N 2.94Å; F350-S354 PolarHBondContact O-OG 3.5Å; F350-S354 VanDerWaalsContact O-OG 3.06Å; F350-Y493 HydrophobicContact CD1-CD1 4.3Å; F350-Y493 HydrophobicContact CD1-CE1 4.33Å; F350-P494 HydrophobicContact CE2-CG 4.4Å; F350-P494 HydrophobicContact CZ-CG 4Å
351	R	91.4	Very high	90.1	Very high	149 Å²	149	62.9 Å²	62.9	56%	0.562	30%	0.296	S	S	*	.	H	α-helix	trans	-51.5	-45.5	-171.8	-178.4	176.9	175.6	-174.5	-0.7	113.7	L345 S347 L355	L345-R351 WeakPolarHBondContact O-CA 3.38Å; S347-R351 VanDerWaalsContact O-CB 3.23Å; S347-R351 WeakPolarHBondContact O-CB 3.38Å; S347-R351 PolarHBondContact O-N 3.23Å; R351-L355 HydrophobicContact CG-CD1 3.96Å; R351-L355 WeakPolarHBondContact O-CB 3.36Å; R351-L355 VanDerWaalsContact O-CG 3.27Å; R351-L355 WeakPolarHBondContact O-CG 3.13Å; R351-L355 PolarHBondContact O-N 3.3Å
352	R	92.9	Very high	91	Very high	137 Å²	137	62 Å²	62	52%	0.517	29%	0.285	S	S	.	.	H	α-helix	trans	-62	-47.6	176.8	176.9	174.9	171.4	163.9	-2.2	111.2	F350 L356 L548	F350-R352 VanDerWaalsContact C-N 3.33Å; F350-R352 PolarHBondContact O-N 3.39Å; F350-R352 VanDerWaalsContact O-N 3.17Å; R352-L356 HydrophobicContact CG-CD1 3.93Å; R352-L356 WeakPolarHBondContact O-CB 3.41Å; R352-L356 VanDerWaalsContact O-CG 3.25Å; R352-L356 WeakPolarHBondContact O-CG 3.13Å; R352-L356 PolarHBondContact O-N 2.84Å; R352-L356 VanDerWaalsContact O-N 3.1Å; R352-L548 PolarHBondContact NE-O 3.38Å; R352-L548 PolarHBondContact NH2-O 3.3Å
353	T	92.1	Very high	91.8	Very high	1 Å²	1	55.3 Å²	55.3	1%	0.006	26%	0.26	C	S	.	.	H	α-helix	trans	-65.7	-42.7	-179.4	-45.1	0	0	0	0	111.5	F350 L357 V492 L549 P550	F350-T353 CarbonylContact O-C 3.45Å; F350-T353 WeakPolarHBondContact O-CA 3.4Å; F350-T353 WeakPolarHBondContact O-CB 3.29Å; F350-T353 PolarHBondContact O-N 3.23Å; T353-L357 HydrophobicContact CG2-CD1 4.02Å; T353-L357 WeakPolarHBondContact O-CB 3.46Å; T353-L357 VanDerWaalsContact O-CG 3.31Å; T353-L357 WeakPolarHBondContact O-CG 3.32Å; T353-L357 PolarHBondContact O-N 2.99Å; T353-V492 HydrophobicContact CG2-CG1 3.66Å; T353-L549 HydrophobicContact CG2-CD2 4.26Å; T353-P550 VanDerWaalsContact OG1-CG 3.26Å; T353-P550 WeakPolarHBondContact OG1-CG 3.44Å
354	S	93.5	Very high	92.3	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-59.8	-51.1	176.2	-54.7	0	0	0	0	112	L345 F350 L356 L357 W358 Y493	L345-S354 WeakPolarHBondContact O-CB 3.39Å; L345-S354 PolarHBondContact O-OG 2.77Å; F350-S354 PolarHBondContact O-N 2.94Å; F350-S354 PolarHBondContact O-OG 3.5Å; F350-S354 VanDerWaalsContact O-OG 3.06Å; S354-L356 PolarHBondContact O-N 3.19Å; S354-L357 PolarHBondContact O-N 3.37Å; S354-W358 VanDerWaalsContact O-CD1 3.22Å; S354-W358 PolarHBondContact O-N 3.37Å; S354-Y493 WeakPolarHBondContact CA-OH 3.24Å; S354-Y493 PolarHBondContact OG-OH 3Å
355	L	94.6	Very high	92.8	Very high	85 Å²	85	44.1 Å²	44.1	45%	0.445	21%	0.214	S	C	.	.	H	α-helix	trans	-62.1	-43.7	-179.8	-71.7	169	0	0	0	112.3	R351 W358 Y359	R351-L355 HydrophobicContact CG-CD1 3.96Å; R351-L355 WeakPolarHBondContact O-CB 3.36Å; R351-L355 VanDerWaalsContact O-CG 3.27Å; R351-L355 WeakPolarHBondContact O-CG 3.13Å; R351-L355 PolarHBondContact O-N 3.3Å; L355-W358 HydrophobicContact CD2-CE3 3.85Å; L355-W358 HydrophobicContact CD2-CZ3 3.78Å; L355-W358 PolarHBondContact O-N 3.28Å; L355-Y359 PolarHBondContact O-N 3.09Å
356	L	95.4	Very high	93.4	Very high	36 Å²	36	44.4 Å²	44.4	19%	0.188	22%	0.215	C	C	.	.	H	α-helix	trans	-64.2	-40	176.1	-69.4	172.9	0	0	0	111.6	R352 S354 Y359 S360 L548 L549	R352-L356 HydrophobicContact CG-CD1 3.93Å; R352-L356 WeakPolarHBondContact O-CB 3.41Å; R352-L356 VanDerWaalsContact O-CG 3.25Å; R352-L356 WeakPolarHBondContact O-CG 3.13Å; R352-L356 PolarHBondContact O-N 2.84Å; R352-L356 VanDerWaalsContact O-N 3.1Å; S354-L356 PolarHBondContact O-N 3.19Å; L356-Y359 PolarHBondContact O-N 2.9Å; L356-S360 WeakPolarHBondContact O-CB 3.45Å; L356-S360 PolarHBondContact O-N 2.99Å; L356-L548 HydrophobicContact CD1-CB 4.49Å; L356-L549 HydrophobicContact CB-CD2 3.7Å; L356-L549 HydrophobicContact CD1-CD2 3.95Å; L356-L549 HydrophobicContact CD1-CG 4.37Å; L356-L549 HydrophobicContact CG-CD2 4.5Å
357	L	94.6	Very high	93.7	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-69.4	-39.6	177.1	-75.9	171.2	0	0	0	113.1	T353 S354 Y359 S360 W361 Y488 V492 Y493	T353-L357 HydrophobicContact CG2-CD1 4.02Å; T353-L357 WeakPolarHBondContact O-CB 3.46Å; T353-L357 VanDerWaalsContact O-CG 3.31Å; T353-L357 WeakPolarHBondContact O-CG 3.32Å; T353-L357 PolarHBondContact O-N 2.99Å; S354-L357 PolarHBondContact O-N 3.37Å; L357-Y359 VanDerWaalsContact C-N 3.27Å; L357-Y359 PolarHBondContact O-N 2.84Å; L357-S360 WeakPolarHBondContact O-CB 3.37Å; L357-S360 PolarHBondContact O-N 3.37Å; L357-S360 VanDerWaalsContact O-N 3.14Å; L357-W361 WeakPolarHBondContact O-CB 3.41Å; L357-W361 VanDerWaalsContact O-CD1 3.23Å; L357-W361 PolarHBondContact O-N 2.7Å; L357-Y488 HydrophobicContact CD1-CD1 4.47Å; L357-Y488 HydrophobicContact CD1-CE1 4.24Å; L357-Y488 HydrophobicContact CD2-CD1 3.59Å; L357-Y488 HydrophobicContact CD2-CE1 3.73Å; L357-Y488 HydrophobicContact CG-CE1 4.31Å; L357-V492 HydrophobicContact CD1-CG1 4.37Å; L357-Y493 HydrophobicContact CD1-CE2 4.01Å
358	W	95.8	Very high	94.1	Very high	18 Å²	18	39.1 Å²	39.1	7%	0.068	19%	0.188	C	C	.	.	H	α-helix	trans	-58.9	-42.2	175.3	-63.6	-11.6	0	0	0	111.5	L345 F346 S354 L355 F362 F504 F508	L345-W358 HydrophobicContact CB-CZ2 4.45Å; F346-W358 AromaticContact CE1-CH2 3.77Å; F346-W358 HydrophobicContact CE1-CH2 3.77Å; F346-W358 HydrophobicContact CE1-CZ3 4.14Å; F346-W358 HydrophobicContact CE2-CH2 4.01Å; F346-W358 AromaticContact CZ-CH2 3.5Å; F346-W358 HydrophobicContact CZ-CH2 3.5Å; F346-W358 HydrophobicContact CZ-CZ3 4.12Å; S354-W358 VanDerWaalsContact O-CD1 3.22Å; S354-W358 PolarHBondContact O-N 3.37Å; L355-W358 HydrophobicContact CD2-CE3 3.85Å; L355-W358 HydrophobicContact CD2-CZ3 3.78Å; L355-W358 PolarHBondContact O-N 3.28Å; W358-F362 WeakPolarHBondContact O-CB 3.44Å; W358-F362 PolarHBondContact O-N 3.26Å; W358-F504 HydrophobicContact CZ2-CB 4.32Å; W358-F504 HydrophobicContact CZ2-CD1 4.18Å; W358-F504 HydrophobicContact CZ2-CG 4.4Å; W358-F508 HydrophobicContact CB-CB 4.23Å; W358-F508 HydrophobicContact CB-CD1 4.16Å; W358-F508 HydrophobicContact CB-CD2 3.54Å; W358-F508 HydrophobicContact CB-CE1 4.44Å; W358-F508 HydrophobicContact CB-CE2 3.86Å; W358-F508 HydrophobicContact CB-CG 3.72Å; W358-F508 HydrophobicContact CB-CZ 4.31Å; W358-F508 AromaticContact CD1-CD2 3.9Å; W358-F508 AromaticContact CD2-CD2 3.83Å; W358-F508 HydrophobicContact CD2-CD2 3.83Å; W358-F508 AromaticContact CD2-CE2 3.39Å; W358-F508 HydrophobicContact CD2-CE2 3.39Å; W358-F508 HydrophobicContact CD2-CZ 4.06Å; W358-F508 HydrophobicContact CE3-CD2 4.3Å; W358-F508 AromaticContact CE3-CE2 3.46Å; W358-F508 HydrophobicContact CE3-CE2 3.46Å; W358-F508 VanDerWaalsContact CE3-CE2 3.46Å; W358-F508 AromaticContact CE3-CZ 3.67Å; W358-F508 HydrophobicContact CE3-CZ 3.67Å; W358-F508 AromaticContact CG-CD2 3.45Å; W358-F508 HydrophobicContact CG-CD2 3.45Å; W358-F508 VanDerWaalsContact CG-CD2 3.45Å; W358-F508 AromaticContact CG-CE2 3.56Å; W358-F508 HydrophobicContact CG-CE2 3.56Å; W358-F508 HydrophobicContact CG-CG 4.16Å; W358-F508 HydrophobicContact CG-CZ 4.33Å; W358-F508 HydrophobicContact CZ3-CE2 4.22Å; W358-F508 HydrophobicContact CZ3-CZ 4.38Å; W358-F508 WeakPolarHBondContact O-CB 3.34Å
359	Y	96.7	Very high	94.5	Very high	75 Å²	75	33.5 Å²	33.5	29%	0.294	15%	0.15	S	C	.	.	H	α-helix	trans	-67.2	-41.8	173.2	-171.6	-109.5	0	0	0	112.5	L355 L356 L357 W361 F362 V363 A538 I541 C542	L355-Y359 PolarHBondContact O-N 3.09Å; L356-Y359 PolarHBondContact O-N 2.9Å; L357-Y359 VanDerWaalsContact C-N 3.27Å; L357-Y359 PolarHBondContact O-N 2.84Å; Y359-W361 PolarHBondContact O-N 2.93Å; Y359-F362 HydrophobicContact CD2-CD1 4.18Å; Y359-F362 HydrophobicContact CE2-CD1 4.06Å; Y359-F362 HydrophobicContact CE2-CE1 4.43Å; Y359-F362 WeakPolarHBondContact O-CB 3.47Å; Y359-F362 PolarHBondContact O-N 3.15Å; Y359-V363 HydrophobicContact CD1-CG2 4.15Å; Y359-V363 HydrophobicContact CD2-CG2 4.32Å; Y359-V363 HydrophobicContact CE1-CG2 3.67Å; Y359-V363 HydrophobicContact CE2-CG2 3.86Å; Y359-V363 HydrophobicContact CG-CG2 4.45Å; Y359-V363 WeakPolarHBondContact O-CG2 3.23Å; Y359-V363 PolarHBondContact O-N 3.38Å; Y359-A538 PolarHBondContact OH-O 3.26Å; Y359-I541 HydrophobicContact CE1-CB 4.19Å; Y359-I541 HydrophobicContact CE1-CG2 3.73Å; Y359-C542 HydrophobicContact CD1-CB 4.18Å; Y359-C542 HydrophobicContact CE1-CB 3.78Å
360	S	96.3	Very high	94.9	Very high	0 Å²	0	28.3 Å²	28.3	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-59.7	-42.8	177.3	-157.3	0	0	0	0	112.4	L356 L357 V363 A364 N546	L356-S360 WeakPolarHBondContact O-CB 3.45Å; L356-S360 PolarHBondContact O-N 2.99Å; L357-S360 WeakPolarHBondContact O-CB 3.37Å; L357-S360 PolarHBondContact O-N 3.37Å; L357-S360 VanDerWaalsContact O-N 3.14Å; S360-V363 PolarHBondContact O-N 3.18Å; S360-A364 WeakPolarHBondContact O-CB 3.38Å; S360-A364 PolarHBondContact O-N 3.14Å; S360-N546 PolarHBondContact OG-OD1 3.04Å
361	W	96.3	Very high	95.3	Very high	0 Å²	0	27 Å²	27	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-69.9	-37.6	174.6	-84.8	82.9	0	0	0	113.7	L357 Y359 S365 F482 V485 Y486 T489 M502 C505 T506 S509	L357-W361 WeakPolarHBondContact O-CB 3.41Å; L357-W361 VanDerWaalsContact O-CD1 3.23Å; L357-W361 PolarHBondContact O-N 2.7Å; Y359-W361 PolarHBondContact O-N 2.93Å; W361-S365 WeakPolarHBondContact O-CB 3.36Å; W361-S365 PolarHBondContact O-N 3.01Å; W361-F482 HydrophobicContact CE3-CE1 4.29Å; W361-F482 HydrophobicContact CZ3-CE1 4.42Å; W361-V485 HydrophobicContact CD2-CG1 3.69Å; W361-V485 HydrophobicContact CG-CG1 3.61Å; W361-V485 HydrophobicContact CZ2-CG1 4.33Å; W361-Y486 AromaticContact CH2-CD1 3.55Å; W361-Y486 HydrophobicContact CH2-CD1 3.55Å; W361-Y486 AromaticContact CH2-CD2 3.92Å; W361-Y486 HydrophobicContact CH2-CD2 3.92Å; W361-Y486 AromaticContact CH2-CE1 3.37Å; W361-Y486 HydrophobicContact CH2-CE1 3.37Å; W361-Y486 AromaticContact CH2-CE2 3.75Å; W361-Y486 HydrophobicContact CH2-CE2 3.75Å; W361-Y486 AromaticContact CH2-CG 3.82Å; W361-Y486 HydrophobicContact CH2-CG 3.82Å; W361-Y486 AromaticContact CH2-CZ 3.45Å; W361-Y486 VanDerWaalsContact CH2-CZ 3.45Å; W361-Y486 HydrophobicContact CZ2-CD1 4.15Å; W361-Y486 HydrophobicContact CZ2-CE1 4.38Å; W361-Y486 HydrophobicContact CZ2-CG 4.24Å; W361-Y486 HydrophobicContact CZ3-CD1 4.45Å; W361-Y486 HydrophobicContact CZ3-CD2 4.2Å; W361-Y486 AromaticContact CZ3-CE1 3.99Å; W361-Y486 HydrophobicContact CZ3-CE1 3.99Å; W361-Y486 AromaticContact CZ3-CE2 3.69Å; W361-Y486 HydrophobicContact CZ3-CE2 3.69Å; W361-Y486 AromaticContact CZ3-CZ 3.55Å; W361-T489 HydrophobicContact CZ2-CG2 4.25Å; W361-T489 PolarHBondContact NE1-OG1 3.01Å; W361-M502 HydrophobicContact CH2-CG 4.38Å; W361-M502 HydrophobicContact CZ2-CG 4.22Å; W361-C505 HydrophobicContact CB-CB 4.37Å; W361-C505 WeakPolarHBondContact CB-O 3.5Å; W361-C505 VanDerWaalsContact CD1-CB 3.46Å; W361-C505 HydrophobicContact CD2-CB 3.74Å; W361-C505 HydrophobicContact CG-CB 3.63Å; W361-C505 HydrophobicContact CZ2-CB 4.15Å; W361-T506 HydrophobicContact CE3-CG2 4.25Å; W361-T506 HydrophobicContact CH2-CG2 3.48Å; W361-T506 VanDerWaalsContact CH2-CG2 3.48Å; W361-T506 HydrophobicContact CZ2-CG2 4.42Å; W361-T506 HydrophobicContact CZ3-CG2 3.41Å; W361-T506 VanDerWaalsContact CZ3-CG2 3.41Å; W361-S509 WeakPolarHBondContact O-CA 3.37Å; W361-S509 WeakPolarHBondContact O-CB 3.42Å
362	F	97	Very high	95.5	Very high	36 Å²	36	20.2 Å²	20.2	16%	0.158	9%	0.088	C	C	.	.	H	α-helix	trans	-57.6	-51.7	170.7	167.6	-93.8	0	0	0	110.4	W358 Y359 S365 F366 I511 G512 I515	W358-F362 WeakPolarHBondContact O-CB 3.44Å; W358-F362 PolarHBondContact O-N 3.26Å; Y359-F362 HydrophobicContact CD2-CD1 4.18Å; Y359-F362 HydrophobicContact CE2-CD1 4.06Å; Y359-F362 HydrophobicContact CE2-CE1 4.43Å; Y359-F362 WeakPolarHBondContact O-CB 3.47Å; Y359-F362 PolarHBondContact O-N 3.15Å; F362-S365 PolarHBondContact O-N 3.39Å; F362-F366 HydrophobicContact CE1-CB 4.41Å; F362-F366 HydrophobicContact CE1-CD1 4.5Å; F362-F366 HydrophobicContact CE1-CG 4.45Å; F362-F366 HydrophobicContact CZ-CB 4.44Å; F362-F366 HydrophobicContact CZ-CG 4.38Å; F362-F366 WeakPolarHBondContact O-CB 3.42Å; F362-F366 PolarHBondContact O-N 2.76Å; F362-I511 HydrophobicContact CD2-CB 4.11Å; F362-I511 HydrophobicContact CD2-CG2 4.19Å; F362-I511 HydrophobicContact CE2-CB 4.37Å; F362-I511 HydrophobicContact CE2-CG2 4.02Å; F362-G512 VanDerWaalsContact CD2-N 3.3Å; F362-G512 VanDerWaalsContact CE2-CA 3.45Å; F362-I515 HydrophobicContact CE2-CD1 4.04Å; F362-I515 HydrophobicContact CZ-CD1 4.23Å
363	V	97.7	Very high	95.5	Very high	0 Å²	0	14.1 Å²	14.1	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-68.2	-39.4	-177.9	176.9	0	0	0	0	112.3	Y359 S360 S365 F366 A367 A538 C542	Y359-V363 HydrophobicContact CD1-CG2 4.15Å; Y359-V363 HydrophobicContact CD2-CG2 4.32Å; Y359-V363 HydrophobicContact CE1-CG2 3.67Å; Y359-V363 HydrophobicContact CE2-CG2 3.86Å; Y359-V363 HydrophobicContact CG-CG2 4.45Å; Y359-V363 WeakPolarHBondContact O-CG2 3.23Å; Y359-V363 PolarHBondContact O-N 3.38Å; S360-V363 PolarHBondContact O-N 3.18Å; V363-S365 VanDerWaalsContact C-N 3.3Å; V363-S365 PolarHBondContact O-N 3.15Å; V363-F366 PolarHBondContact O-N 2.86Å; V363-A367 WeakPolarHBondContact O-CB 3.31Å; V363-A367 PolarHBondContact O-N 3.44Å; V363-A538 HydrophobicContact CG1-CB 4.31Å; V363-A538 HydrophobicContact CG2-CB 4.08Å; V363-C542 HydrophobicContact CB-CB 3.96Å; V363-C542 HydrophobicContact CG1-CB 3.83Å; V363-C542 HydrophobicContact CG2-CB 3.95Å
364	A	96.1	Very high	95.5	Very high	0 Å²	0	14.2 Å²	14.2	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-56.7	-44.9	174.8	0	0	0	0	0	111.9	S360 Y368 F482	S360-A364 WeakPolarHBondContact O-CB 3.38Å; S360-A364 PolarHBondContact O-N 3.14Å; A364-Y368 VanDerWaalsContact O-CB 3.29Å; A364-Y368 WeakPolarHBondContact O-CB 3.41Å; A364-Y368 PolarHBondContact O-N 3.39Å; A364-F482 HydrophobicContact CB-CD1 4.12Å; A364-F482 HydrophobicContact CB-CD2 4.32Å; A364-F482 HydrophobicContact CB-CE1 4.16Å; A364-F482 HydrophobicContact CB-CE2 4.38Å; A364-F482 HydrophobicContact CB-CG 4.2Å; A364-F482 HydrophobicContact CB-CZ 4.3Å; A364-F482 WeakPolarHBondContact O-CE2 3.33Å
365	S	95.5	Very high	95.4	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-71.9	-43.9	178.2	-168.4	0	0	0	0	113.2	W361 F362 V363 Y368 Y369 S509	W361-S365 WeakPolarHBondContact O-CB 3.36Å; W361-S365 PolarHBondContact O-N 3.01Å; F362-S365 PolarHBondContact O-N 3.39Å; V363-S365 VanDerWaalsContact C-N 3.3Å; V363-S365 PolarHBondContact O-N 3.15Å; S365-Y368 PolarHBondContact O-N 3.4Å; S365-Y369 WeakPolarHBondContact O-CD2 3.4Å; S365-Y369 PolarHBondContact O-N 2.7Å; S365-Y369 WeakPolarHBondContact OG-CD2 3.23Å; S365-Y369 VanDerWaalsContact OG-CE2 3.28Å; S365-Y369 WeakPolarHBondContact OG-CE2 3.25Å; S365-S509 WeakPolarHBondContact CB-O 3.28Å; S365-S509 PolarHBondContact OG-O 3.3Å
366	F	97.1	Very high	95.2	Very high	7 Å²	7	10.2 Å²	10.2	3%	0.031	5%	0.046	C	C	.	.	H	α-helix	trans	-59.9	-46.3	176.9	176.6	-118.6	0	0	0	111.3	F362 V363 G370 I515 A516 I519 P534 F535 A538	F362-F366 HydrophobicContact CE1-CB 4.41Å; F362-F366 HydrophobicContact CE1-CD1 4.5Å; F362-F366 HydrophobicContact CE1-CG 4.45Å; F362-F366 HydrophobicContact CZ-CB 4.44Å; F362-F366 HydrophobicContact CZ-CG 4.38Å; F362-F366 WeakPolarHBondContact O-CB 3.42Å; F362-F366 PolarHBondContact O-N 2.76Å; V363-F366 PolarHBondContact O-N 2.86Å; F366-G370 VanDerWaalsContact O-CA 3.29Å; F366-G370 WeakPolarHBondContact O-CA 3.26Å; F366-G370 PolarHBondContact O-N 3.48Å; F366-I515 HydrophobicContact CD2-CB 4.46Å; F366-I515 HydrophobicContact CD2-CG2 4.36Å; F366-I515 HydrophobicContact CE2-CB 4.49Å; F366-I515 HydrophobicContact CE2-CG2 3.93Å; F366-A516 HydrophobicContact CD2-CB 3.9Å; F366-A516 HydrophobicContact CE2-CB 4.35Å; F366-I519 HydrophobicContact CE2-CD1 4.03Å; F366-I519 HydrophobicContact CZ-CD1 3.84Å; F366-P534 HydrophobicContact CZ-CB 4.38Å; F366-F535 AromaticContact CD1-CD1 3.72Å; F366-F535 HydrophobicContact CD1-CD1 3.72Å; F366-F535 HydrophobicContact CD1-CE1 4.15Å; F366-F535 HydrophobicContact CD2-CD1 4.13Å; F366-F535 AromaticContact CD2-CE1 3.68Å; F366-F535 HydrophobicContact CD2-CE1 3.68Å; F366-F535 HydrophobicContact CE1-CB 4.47Å; F366-F535 AromaticContact CE1-CD1 3.36Å; F366-F535 HydrophobicContact CE1-CD1 3.36Å; F366-F535 AromaticContact CE1-CE1 3.83Å; F366-F535 HydrophobicContact CE1-CE1 3.83Å; F366-F535 HydrophobicContact CE1-CG 4.13Å; F366-F535 AromaticContact CE2-CD1 3.78Å; F366-F535 HydrophobicContact CE2-CD1 3.78Å; F366-F535 AromaticContact CE2-CE1 3.29Å; F366-F535 HydrophobicContact CE2-CE1 3.29Å; F366-F535 HydrophobicContact CE2-CZ 4.06Å; F366-F535 HydrophobicContact CG-CD1 4.08Å; F366-F535 HydrophobicContact CG-CE1 4.06Å; F366-F535 AromaticContact CZ-CD1 3.36Å; F366-F535 HydrophobicContact CZ-CD1 3.36Å; F366-F535 AromaticContact CZ-CE1 3.36Å; F366-F535 HydrophobicContact CZ-CE1 3.36Å; F366-F535 HydrophobicContact CZ-CG 4.15Å; F366-F535 HydrophobicContact CZ-CZ 4.16Å; F366-F535 VanDerWaalsContact O-CE1 3.27Å; F366-F535 WeakPolarHBondContact O-CE1 3.41Å; F366-A538 HydrophobicContact CD1-CB 3.96Å; F366-A538 HydrophobicContact CE1-CB 3.85Å
367	A	97.3	Very high	94.8	Very high	1 Å²	1	8.5 Å²	8.5	1%	0.008	4%	0.037	C	C	.	.	H	α-helix	trans	-65.1	-37.1	173.7	0	0	0	0	0	112.5	V363 S371 F455 V478	V363-A367 WeakPolarHBondContact O-CB 3.31Å; V363-A367 PolarHBondContact O-N 3.44Å; A367-S371 WeakPolarHBondContact O-CB 3.49Å; A367-S371 PolarHBondContact O-N 3.42Å; A367-S371 PolarHBondContact O-OG 3.34Å; A367-F455 HydrophobicContact CB-CE2 3.96Å; A367-F455 HydrophobicContact CB-CZ 4.33Å; A367-V478 HydrophobicContact CB-CG1 3.99Å; A367-V478 HydrophobicContact CB-CG2 4.22Å
368	Y	95.7	Very high	94.5	Very high	9 Å²	9	8.7 Å²	8.7	4%	0.035	4%	0.038	C	C	.	.	H	α-helix	trans	-67.4	-62.1	-177.5	-178.7	-106.3	0	0	0	110.9	M139 W254 A364 S365 G370 S371 V372 E424 V478 F482	M139-Y368 HydrophobicContact CE-CE1 3.96Å; W254-Y368 HydrophobicContact CZ2-CE1 4.17Å; W254-Y368 AromaticContact NE1-CZ 3.67Å; W254-Y368 PolarHBondContact NE1-OH 2.87Å; A364-Y368 VanDerWaalsContact O-CB 3.29Å; A364-Y368 WeakPolarHBondContact O-CB 3.41Å; A364-Y368 PolarHBondContact O-N 3.39Å; S365-Y368 PolarHBondContact O-N 3.4Å; Y368-G370 PolarHBondContact O-N 3.18Å; Y368-S371 PolarHBondContact O-N 3.41Å; Y368-S371 PolarHBondContact O-OG 2.73Å; Y368-V372 HydrophobicContact CE1-CG2 4.26Å; Y368-V372 HydrophobicContact CE2-CG2 4.5Å; Y368-V372 WeakPolarHBondContact O-CG2 3.44Å; Y368-V372 PolarHBondContact O-N 3.31Å; Y368-E424 WeakPolarHBondContact CE2-OE1 3.33Å; Y368-E424 PolarHBondContact OH-OE1 2.93Å; Y368-V478 VanDerWaalsContact CA-CG1 3.4Å; Y368-V478 HydrophobicContact CD2-CG1 4.11Å; Y368-V478 HydrophobicContact CG-CG1 4.4Å; Y368-F482 HydrophobicContact CD1-CE2 4.31Å; Y368-F482 HydrophobicContact CD2-CD2 4.5Å; Y368-F482 HydrophobicContact CG-CD2 4.14Å; Y368-F482 AromaticContact CG-CE2 3.96Å; Y368-F482 HydrophobicContact CG-CE2 3.96Å
369	Y	95.3	Very high	94.1	Very high	10 Å²	10	7.9 Å²	7.9	4%	0.039	4%	0.035	C	C	.	.	H	α-helix	trans	-64.5	-29.8	178.1	-60.5	-61.1	0	0	0	111.7	I138 M139 F167 S365 V372 L373	I138-Y369 HydrophobicContact CG2-CD1 4.38Å; I138-Y369 HydrophobicContact CG2-CE1 3.55Å; M139-Y369 HydrophobicContact CE-CD1 3.92Å; M139-Y369 HydrophobicContact CE-CE1 3.74Å; F167-Y369 HydrophobicContact CE1-CD1 4.47Å; F167-Y369 HydrophobicContact CE1-CD2 4.1Å; F167-Y369 HydrophobicContact CE1-CE1 4.03Å; F167-Y369 AromaticContact CE1-CE2 3.6Å; F167-Y369 HydrophobicContact CE1-CE2 3.6Å; F167-Y369 AromaticContact CE1-CZ 3.56Å; F167-Y369 HydrophobicContact CE2-CG 4.41Å; F167-Y369 AromaticContact CZ-CD1 3.7Å; F167-Y369 HydrophobicContact CZ-CD1 3.7Å; F167-Y369 AromaticContact CZ-CD2 3.8Å; F167-Y369 HydrophobicContact CZ-CD2 3.8Å; F167-Y369 AromaticContact CZ-CE1 3.63Å; F167-Y369 HydrophobicContact CZ-CE1 3.63Å; F167-Y369 AromaticContact CZ-CE2 3.72Å; F167-Y369 HydrophobicContact CZ-CE2 3.72Å; F167-Y369 AromaticContact CZ-CG 3.78Å; F167-Y369 HydrophobicContact CZ-CG 3.78Å; F167-Y369 AromaticContact CZ-CZ 3.63Å; S365-Y369 WeakPolarHBondContact O-CD2 3.4Å; S365-Y369 PolarHBondContact O-N 2.7Å; S365-Y369 WeakPolarHBondContact OG-CD2 3.23Å; S365-Y369 VanDerWaalsContact OG-CE2 3.28Å; S365-Y369 WeakPolarHBondContact OG-CE2 3.25Å; Y369-V372 PolarHBondContact O-N 3.21Å; Y369-L373 WeakPolarHBondContact O-CB 3.28Å; Y369-L373 WeakPolarHBondContact O-CG 3.24Å; Y369-L373 PolarHBondContact O-N 2.99Å
370	G	95.1	Very high	93.3	Very high	0 Å²	0	4.3 Å²	4.3	0%	0	2%	0.021	C	C	.	.	H	α-helix	trans	-58.5	-48.2	169	0	0	0	0	0	112.8	F366 Y368 S374 F535	F366-G370 VanDerWaalsContact O-CA 3.29Å; F366-G370 WeakPolarHBondContact O-CA 3.26Å; F366-G370 PolarHBondContact O-N 3.48Å; Y368-G370 PolarHBondContact O-N 3.18Å; G370-S374 WeakPolarHBondContact O-CB 3.33Å; G370-S374 PolarHBondContact O-N 3.34Å; G370-S374 PolarHBondContact O-OG 2.86Å; G370-F535 VanDerWaalsContact CA-CZ 3.45Å
371	S	95.5	Very high	92.2	Very high	2 Å²	2	5 Å²	5	1%	0.014	2%	0.024	C	C	.	.	H	α-helix	trans	-64.4	-40.2	177.3	73.4	0	0	0	0	112.3	A367 Y368 S375	A367-S371 WeakPolarHBondContact O-CB 3.49Å; A367-S371 PolarHBondContact O-N 3.42Å; A367-S371 PolarHBondContact O-OG 3.34Å; Y368-S371 PolarHBondContact O-N 3.41Å; Y368-S371 PolarHBondContact O-OG 2.73Å; S371-S375 VanDerWaalsContact O-CB 3.29Å; S371-S375 WeakPolarHBondContact O-CB 3.25Å; S371-S375 PolarHBondContact O-N 3.3Å; S371-S375 VanDerWaalsContact O-N 3.14Å; S371-S375 PolarHBondContact O-OG 3.46Å
372	V	94.6	Very high	91	Very high	7 Å²	7	5.7 Å²	5.7	4%	0.042	3%	0.027	C	C	.	.	H	α-helix	trans	-64.5	-58.5	177.1	-173.6	0	0	0	0	110.6	M139 A142 Y368 Y369 S374 S375 S376 R475	M139-V372 HydrophobicContact CE-CG1 4.37Å; M139-V372 HydrophobicContact CE-CG2 4.23Å; M139-V372 HydrophobicContact SD-CB 4.5Å; M139-V372 HydrophobicContact SD-CG1 3.81Å; M139-V372 HydrophobicContact SD-CG2 3.97Å; A142-V372 HydrophobicContact CB-CG1 3.78Å; Y368-V372 HydrophobicContact CE1-CG2 4.26Å; Y368-V372 HydrophobicContact CE2-CG2 4.5Å; Y368-V372 WeakPolarHBondContact O-CG2 3.44Å; Y368-V372 PolarHBondContact O-N 3.31Å; Y369-V372 PolarHBondContact O-N 3.21Å; V372-S374 PolarHBondContact O-N 3.49Å; V372-S375 PolarHBondContact O-N 2.97Å; V372-S375 PolarHBondContact O-OG 3.02Å; V372-S376 PolarHBondContact O-N 3.36Å; V372-S376 PolarHBondContact O-OG 3.05Å; V372-R475 VanDerWaalsContact CG2-NH2 3.35Å
373	L	93.3	Very high	89.6	Confident	9 Å²	9	7 Å²	7	5%	0.047	4%	0.036	C	C	.	.	H	α-helix	trans	-70.8	-34.1	-172.8	-64.6	171.5	0	0	0	112.3	A142 Y369 S375 S376 E377 P517 A520	A142-L373 HydrophobicContact CB-CD2 4.1Å; Y369-L373 WeakPolarHBondContact O-CB 3.28Å; Y369-L373 WeakPolarHBondContact O-CG 3.24Å; Y369-L373 PolarHBondContact O-N 2.99Å; L373-S375 VanDerWaalsContact C-N 3.33Å; L373-S376 WeakPolarHBondContact CA-OG 3.14Å; L373-S376 PolarHBondContact O-N 3.3Å; L373-S376 PolarHBondContact O-OG 3.43Å; L373-E377 VanDerWaalsContact O-CG 3.24Å; L373-E377 WeakPolarHBondContact O-CG 3.16Å; L373-E377 PolarHBondContact O-N 3.48Å; L373-P517 HydrophobicContact CD1-CB 3.84Å; L373-P517 HydrophobicContact CD1-CG 3.64Å; L373-A520 HydrophobicContact CB-CB 3.66Å
374	S	92.8	Very high	88.3	Confident	4 Å²	4	8.2 Å²	8.2	3%	0.028	4%	0.042	C	C	.	.	H	α-helix	trans	-66.3	-37.7	173.7	-56.1	0	0	0	0	111	G370 V372 E377 L378	G370-S374 WeakPolarHBondContact O-CB 3.33Å; G370-S374 PolarHBondContact O-N 3.34Å; G370-S374 PolarHBondContact O-OG 2.86Å; V372-S374 PolarHBondContact O-N 3.49Å; S374-E377 PolarHBondContact O-N 3.17Å; S374-L378 VanDerWaalsContact O-CB 3.24Å; S374-L378 WeakPolarHBondContact O-CB 3.31Å; S374-L378 WeakPolarHBondContact O-CD1 3.43Å; S374-L378 WeakPolarHBondContact O-CG 3.12Å; S374-L378 PolarHBondContact O-N 3.22Å
375	S	91.5	Very high	87	Confident	1 Å²	1	11.6 Å²	11.6	1%	0.007	7%	0.065	C	C	.	.	H	α-helix	trans	-64.4	-40.2	177.1	69.7	0	0	0	0	112.7	S371 V372 L373 L379	S371-S375 VanDerWaalsContact O-CB 3.29Å; S371-S375 WeakPolarHBondContact O-CB 3.25Å; S371-S375 PolarHBondContact O-N 3.3Å; S371-S375 VanDerWaalsContact O-N 3.14Å; S371-S375 PolarHBondContact O-OG 3.46Å; V372-S375 PolarHBondContact O-N 2.97Å; V372-S375 PolarHBondContact O-OG 3.02Å; L373-S375 VanDerWaalsContact C-N 3.33Å; S375-L379 WeakPolarHBondContact O-CD1 3.31Å; S375-L379 WeakPolarHBondContact O-CG 3.2Å; S375-L379 PolarHBondContact O-N 2.86Å
376	S	89.6	Confident	85.5	Confident	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-66.7	-46.2	174.9	45.5	0	0	0	0	112.3	A142 V372 L373 L378 L379 E380 F409	A142-S376 WeakPolarHBondContact O-CB 3.44Å; V372-S376 PolarHBondContact O-N 3.36Å; V372-S376 PolarHBondContact O-OG 3.05Å; L373-S376 WeakPolarHBondContact CA-OG 3.14Å; L373-S376 PolarHBondContact O-N 3.3Å; L373-S376 PolarHBondContact O-OG 3.43Å; S376-L378 PolarHBondContact O-N 3.34Å; S376-L379 PolarHBondContact O-N 2.98Å; S376-E380 WeakPolarHBondContact O-CB 3.19Å; S376-E380 PolarHBondContact O-N 2.89Å; S376-F409 WeakPolarHBondContact O-CE1 3.38Å
377	E	88.3	Confident	83.6	Confident	0 Å²	0	18 Å²	18	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-69.9	-33.3	-177.9	-63.9	-81.4	153.1	0	0	112.6	R149 L373 S374 K381 Q521 M524	R149-E377 IonicContact CZ-OE2 3.16Å; R149-E377 IonicContact NH1-OE1 3.45Å; R149-E377 IonicContact NH1-OE2 3.72Å; R149-E377 PolarHBondContact NH1-OE2 3.07Å; R149-E377 VanDerWaalsContact NH1-OE2 3.15Å; R149-E377 IonicContact NH2-OE1 2.71Å; R149-E377 PolarHBondContact NH2-OE1 3.05Å; R149-E377 IonicContact NH2-OE2 3.41Å; R149-E377 PolarHBondContact NH2-OE2 2.91Å; L373-E377 VanDerWaalsContact O-CG 3.24Å; L373-E377 WeakPolarHBondContact O-CG 3.16Å; L373-E377 PolarHBondContact O-N 3.48Å; S374-E377 PolarHBondContact O-N 3.17Å; E377-K381 WeakPolarHBondContact O-CB 3.41Å; E377-K381 WeakPolarHBondContact O-CG 3.28Å; E377-K381 PolarHBondContact O-N 3.06Å; E377-K381 WeakPolarHBondContact OE2-CE 3.32Å; E377-K381 IonicContact OE2-NZ 3.51Å; E377-K381 PolarHBondContact OE2-NZ 3.24Å; E377-K381 VanDerWaalsContact OE2-NZ 3.16Å; E377-Q521 HydrophobicContact CG-CB 4.25Å; E377-Q521 HydrophobicContact CG-CG 3.85Å; E377-Q521 WeakPolarHBondContact OE1-CG 3.45Å; E377-Q521 PolarHBondContact OE1-NE2 2.91Å; E377-M524 HydrophobicContact CB-CG 4.38Å
378	L	88.2	Confident	81.6	Confident	4 Å²	4	23.2 Å²	23.2	2%	0.021	13%	0.127	C	C	.	.	H	α-helix	trans	-64	-43.4	174.4	-78.4	169.5	0	0	0	112	S374 S376 N382 L383 L384 V458 F467 M524 V528	S374-L378 VanDerWaalsContact O-CB 3.24Å; S374-L378 WeakPolarHBondContact O-CB 3.31Å; S374-L378 WeakPolarHBondContact O-CD1 3.43Å; S374-L378 WeakPolarHBondContact O-CG 3.12Å; S374-L378 PolarHBondContact O-N 3.22Å; S376-L378 PolarHBondContact O-N 3.34Å; L378-N382 WeakPolarHBondContact O-CA 3.43Å; L378-N382 PolarHBondContact O-N 3.09Å; L378-L383 HydrophobicContact CD2-CB 4.06Å; L378-L383 PolarHBondContact O-N 3.47Å; L378-L384 HydrophobicContact CB-CD2 3.94Å; L378-V458 HydrophobicContact CD1-CG1 3.93Å; L378-F467 HydrophobicContact CB-CZ 4.26Å; L378-F467 HydrophobicContact CD1-CE2 4.23Å; L378-F467 HydrophobicContact CD1-CZ 4.2Å; L378-M524 HydrophobicContact CD2-SD 3.86Å; L378-M524 HydrophobicContact CG-CE 4.26Å; L378-M524 HydrophobicContact CG-SD 4.15Å; L378-V528 HydrophobicContact CD2-CG1 3.77Å; L378-V528 HydrophobicContact CD2-CG2 3.88Å
379	L	85.4	Confident	79.5	Confident	1 Å²	1	24.2 Å²	24.2	1%	0.005	14%	0.137	C	C	.	.	H	α-helix	trans	-70.4	-40.4	176.9	-74.6	166.1	0	0	0	112.3	S375 S376 L384 K396 F409 D413 T416 L417 M464 F467	S375-L379 WeakPolarHBondContact O-CD1 3.31Å; S375-L379 WeakPolarHBondContact O-CG 3.2Å; S375-L379 PolarHBondContact O-N 2.86Å; S376-L379 PolarHBondContact O-N 2.98Å; L379-L384 HydrophobicContact CD2-CD1 4.19Å; L379-K396 PolarHBondContact O-NZ 3.43Å; L379-F409 HydrophobicContact CB-CE1 3.92Å; L379-D413 HydrophobicContact CB-CB 4.31Å; L379-D413 HydrophobicContact CD2-CB 4.4Å; L379-T416 HydrophobicContact CD1-CG2 4.02Å; L379-T416 HydrophobicContact CD2-CG2 4.19Å; L379-L417 HydrophobicContact CD1-CD1 4.39Å; L379-L417 HydrophobicContact CD1-CD2 3.82Å; L379-L417 HydrophobicContact CD1-CG 3.74Å; L379-M464 HydrophobicContact CD2-CE 4.32Å; L379-F467 HydrophobicContact CD2-CE1 4.11Å; L379-F467 HydrophobicContact CG-CE1 4.28Å
380	E	80.1	Confident	77.3	Confident	0 Å²	0	29.5 Å²	29.5	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-65.2	-54.1	179.7	-174.8	-170.3	159.6	0	0	111.3	P146 R149 S376 N382 F409	P146-E380 WeakPolarHBondContact CA-OE1 3.14Å; P146-E380 VanDerWaalsContact CB-CD 3.49Å; P146-E380 HydrophobicContact CB-CG 3.94Å; R149-E380 WeakPolarHBondContact CD-OE1 3.46Å; R149-E380 IonicContact CZ-OE1 2.81Å; R149-E380 IonicContact CZ-OE2 2.69Å; R149-E380 IonicContact NE-OE1 2.73Å; R149-E380 IonicContact NH1-OE1 3.15Å; R149-E380 PolarHBondContact NH1-OE1 3.08Å; R149-E380 IonicContact NH1-OE2 3.47Å; R149-E380 PolarHBondContact NH1-OE2 3.12Å; S376-E380 WeakPolarHBondContact O-CB 3.19Å; S376-E380 PolarHBondContact O-N 2.89Å; E380-N382 PolarHBondContact O-N 3.42Å; E380-F409 HydrophobicContact CB-CE1 3.87Å; E380-F409 HydrophobicContact CB-CZ 4.32Å
381	K	72.9	Confident	75.2	Confident	15 Å²	15	33.6 Å²	33.6	7%	0.065	20%	0.2	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79	-2.5	-176.4	-58.1	-173.2	-170.6	-175.3	0	113.4	D156 E377 L383 Y405 Q521	D156-K381 VanDerWaalsContact CG-NZ 3.3Å; D156-K381 IonicContact OD1-NZ 3.98Å; D156-K381 PolarHBondContact OD1-NZ 3.19Å; D156-K381 IonicContact OD2-NZ 3.39Å; D156-K381 PolarHBondContact OD2-NZ 2.87Å; E377-K381 WeakPolarHBondContact O-CB 3.41Å; E377-K381 WeakPolarHBondContact O-CG 3.28Å; E377-K381 PolarHBondContact O-N 3.06Å; E377-K381 WeakPolarHBondContact OE2-CE 3.32Å; E377-K381 IonicContact OE2-NZ 3.51Å; E377-K381 PolarHBondContact OE2-NZ 3.24Å; E377-K381 VanDerWaalsContact OE2-NZ 3.16Å; K381-L383 HydrophobicContact CB-CD1 3.66Å; K381-L383 HydrophobicContact CB-CG 3.64Å; K381-L383 HydrophobicContact CD-CD1 3.87Å; K381-L383 HydrophobicContact CG-CD1 4.35Å; K381-L383 PolarHBondContact O-N 3.26Å; K381-Y405 HydrophobicContact CD-CE2 4.14Å; K381-Y405 WeakPolarHBondContact CE-OH 3.23Å; K381-Y405 HydrophobicContact CG-CE2 3.89Å; K381-Y405 PolarHBondContact NZ-OH 3.36Å; K381-Q521 PolarHBondContact NZ-O 3.24Å
382	N	71.6	Confident	73	Confident	14 Å²	14	41.7 Å²	41.7	8%	0.075	24%	0.237	C	C	.	.	T	Hydrogen-bonded Turn	trans	50.8	35.7	-174.2	-161	27.3	0	0	0	113.1	L378 E380 L384 H393 K396	L378-N382 WeakPolarHBondContact O-CA 3.43Å; L378-N382 PolarHBondContact O-N 3.09Å; E380-N382 PolarHBondContact O-N 3.42Å; N382-L384 PolarHBondContact O-N 3.3Å; N382-H393 PolarHBondContact ND2-O 3.16Å; N382-H393 PolarHBondContact OD1-CD2 2.71Å; N382-K396 HydrophobicContact CB-CB 4.27Å; N382-K396 HydrophobicContact CB-CD 4.19Å
383	L	68.1	Low	70.8	Confident	64 Å²	64	42.6 Å²	42.6	34%	0.335	24%	0.241	S	C	.	.			trans	-78.2	24.9	-178.2	-69.6	169.1	0	0	0	112.5	L378 K381 M524 V528	L378-L383 HydrophobicContact CD2-CB 4.06Å; L378-L383 PolarHBondContact O-N 3.47Å; K381-L383 HydrophobicContact CB-CD1 3.66Å; K381-L383 HydrophobicContact CB-CG 3.64Å; K381-L383 HydrophobicContact CD-CD1 3.87Å; K381-L383 HydrophobicContact CG-CD1 4.35Å; K381-L383 PolarHBondContact O-N 3.26Å; L383-M524 HydrophobicContact CD1-CG 3.93Å; L383-M524 WeakPolarHBondContact CD1-O 3.5Å; L383-V528 HydrophobicContact CB-CG2 3.75Å; L383-V528 HydrophobicContact CD1-CG2 4.27Å; L383-V528 HydrophobicContact CG-CG2 4.49Å
384	L	70.9	Confident	68.4	Low	24 Å²	24	47.9 Å²	47.9	13%	0.126	27%	0.266	C	S	.	.			trans	-88.4	126.9	-175.2	-57.7	177.1	0	0	0	109.3	L378 L379 N382 V386 M464 F467	L378-L384 HydrophobicContact CB-CD2 3.94Å; L379-L384 HydrophobicContact CD2-CD1 4.19Å; N382-L384 PolarHBondContact O-N 3.3Å; L384-V386 VanDerWaalsContact C-N 3.32Å; L384-V386 HydrophobicContact CB-CG2 3.46Å; L384-V386 VanDerWaalsContact CB-CG2 3.46Å; L384-V386 HydrophobicContact CD1-CG2 4.24Å; L384-V386 PolarHBondContact O-N 3.36Å; L384-M464 HydrophobicContact CD1-CE 4.01Å; L384-M464 HydrophobicContact CD1-SD 3.83Å; L384-F467 HydrophobicContact CD1-CD1 4.35Å; L384-F467 HydrophobicContact CD1-CE1 4.26Å; L384-F467 HydrophobicContact CD2-CD1 4.1Å; L384-F467 HydrophobicContact CD2-CD2 3.88Å; L384-F467 HydrophobicContact CD2-CE1 3.65Å; L384-F467 HydrophobicContact CD2-CE2 3.41Å; L384-F467 VanDerWaalsContact CD2-CE2 3.41Å; L384-F467 HydrophobicContact CD2-CG 4.2Å; L384-F467 HydrophobicContact CD2-CZ 3.29Å
385	C	68.8	Low	66.2	Low	72 Å²	72	52.9 Å²	52.9	49%	0.486	30%	0.296	S	S	.	.			trans	-78	86.2	166.1	-167.1	0	0	0	0	109.3	C461 T462	C385-C461 HydrophobicContact CB-CB 3.76Å; C385-C461 WeakPolarHBondContact CB-SG 3.48Å; C385-C461 CarbonylContact O-C 3.54Å; C385-C461 WeakPolarHBondContact O-CA 3.34Å; C385-C461 WeakPolarHBondContact SG-CB 3.29Å; C385-C461 CovalentContact SG-SG 2.03Å; C385-C461 PolarHBondContact SG-SG 3.45Å; C385-T462 PolarHBondContact O-N 3.3Å
386	V	64	Low	64.1	Low	26 Å²	26	55.2 Å²	55.2	16%	0.158	31%	0.306	C	S	.	.	B	Isolated β-bridge	trans	-98.9	120	-178.5	-170	0	0	0	0	110.5	L384 A389 T462 M464	L384-V386 VanDerWaalsContact C-N 3.32Å; L384-V386 HydrophobicContact CB-CG2 3.46Å; L384-V386 VanDerWaalsContact CB-CG2 3.46Å; L384-V386 HydrophobicContact CD1-CG2 4.24Å; L384-V386 PolarHBondContact O-N 3.36Å; V386-A389 HydrophobicContact CB-CB 4.15Å; V386-A389 HydrophobicContact CG1-CB 4.3Å; V386-T462 CarbonylContact C-O 3.58Å; V386-T462 VanDerWaalsContact CA-O 3.27Å; V386-T462 WeakPolarHBondContact CA-O 3.45Å; V386-M464 HydrophobicContact CG1-CG 4.06Å; V386-M464 HydrophobicContact CG1-SD 4.23Å; V386-M464 HydrophobicContact CG2-SD 3.69Å
387	I	57.2	Low	62	Low	115 Å²	115	60.5 Å²	60.5	59%	0.59	33%	0.33	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.5	-36.2	-178.4	-60.4	175.6	0	0	0	111.2	C461 T462	I387-C461 HydrophobicContact CD1-CB 4.13Å; I387-C461 WeakPolarHBondContact CD1-O 3.36Å; I387-C461 HydrophobicContact CG1-CB 3.89Å; I387-T462 PolarHBondContact N-O 3.36Å
388	N	54.5	Low	59.7	Low	111 Å²	111	70 Å²	70	59%	0.594	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	-115.8	60.2	178.6	-61.5	-8.2	0	0	0	109.9	D390 T463	N388-D390 PolarHBondContact O-N 3.16Å; N388-T463 HydrophobicContact CB-CG2 4.46Å
389	A	52.5	Low	57.5	Low	30 Å²	30	78.4 Å²	78.4	25%	0.248	41%	0.405	C	S	.	.			trans	-74	113.9	172.7	0	0	0	0	0	109.5	V386 H393 Q394	V386-A389 HydrophobicContact CB-CB 4.15Å; V386-A389 HydrophobicContact CG1-CB 4.3Å; A389-H393 HydrophobicContact CB-CB 4.36Å; A389-Q394 HydrophobicContact CB-CG 4.36Å
390	D	49.1	Very low	55.3	Low	120 Å²	120	85.3 Å²	85.3	64%	0.642	44%	0.437	S	S	*	.			trans	-56.7	155.8	172.7	-69	-51.1	0	0	0	111.2	N388 E392 H393 Q394	N388-D390 PolarHBondContact O-N 3.16Å; D390-E392 PolarHBondContact O-N 3.22Å; D390-H393 PolarHBondContact O-N 3.37Å; D390-Q394 PolarHBondContact O-N 2.62Å
391	A	49.9	Very low	53.5	Low	87 Å²	87	91.5 Å²	91.5	72%	0.719	48%	0.48	S	S	*	.	H	α-helix	trans	-56.3	-28.8	-178.4	0	0	0	0	0	113.1	V395	A391-V395 VanDerWaalsContact O-CG2 3.27Å; A391-V395 WeakPolarHBondContact O-CG2 3.36Å
392	E	49.8	Very low	52.3	Low	171 Å²	171	93.4 Å²	93.4	80%	0.799	51%	0.505	S	S	*	.	H	α-helix	trans	-69	-37.1	172.1	-73.8	-172.3	134	0	0	113.4	D390 Q394 V395	D390-E392 PolarHBondContact O-N 3.22Å; E392-Q394 VanDerWaalsContact C-N 3.3Å; E392-Q394 PolarHBondContact O-N 2.98Å; E392-V395 PolarHBondContact O-N 2.86Å
393	H	48.1	Very low	51.3	Low	27 Å²	27	101 Å²	101	13%	0.125	55%	0.545	C	S	.	.	H	α-helix	trans	-70.5	-27.6	178.1	-114.2	68.9	0	0	0	112.2	N382 A389 D390 V395 M464	N382-H393 PolarHBondContact ND2-O 3.16Å; N382-H393 PolarHBondContact OD1-CD2 2.71Å; A389-H393 HydrophobicContact CB-CB 4.36Å; D390-H393 PolarHBondContact O-N 3.37Å; H393-V395 VanDerWaalsContact C-N 3.29Å; H393-V395 PolarHBondContact O-N 3.08Å; H393-M464 WeakPolarHBondContact NE2-CE 3.39Å
394	Q	43.2	Very low	50.6	Low	119 Å²	119	100.3 Å²	100.3	56%	0.556	54%	0.544	S	S	*	.	H	α-helix	trans	-68.5	-22.9	174.8	-70.3	-77	-20	0	0	113.2	A389 D390 E392 K396 H397	A389-Q394 HydrophobicContact CB-CG 4.36Å; D390-Q394 PolarHBondContact O-N 2.62Å; E392-Q394 VanDerWaalsContact C-N 3.3Å; E392-Q394 PolarHBondContact O-N 2.98Å; Q394-K396 VanDerWaalsContact C-N 3.31Å; Q394-K396 PolarHBondContact O-N 3.45Å; Q394-H397 PolarHBondContact O-N 2.86Å
395	V	45.6	Very low	50.3	Low	109 Å²	109	103.5 Å²	103.5	66%	0.661	56%	0.555	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.1	-22.2	-173.4	-168.5	0	0	0	0	113.3	A391 E392 H393 H397	A391-V395 VanDerWaalsContact O-CG2 3.27Å; A391-V395 WeakPolarHBondContact O-CG2 3.36Å; E392-V395 PolarHBondContact O-N 2.86Å; H393-V395 VanDerWaalsContact C-N 3.29Å; H393-V395 PolarHBondContact O-N 3.08Å; V395-H397 PolarHBondContact O-N 3.16Å; V395-H397 VanDerWaalsContact O-N 3.08Å
396	K	49.3	Very low	50.3	Low	50 Å²	50	103.7 Å²	103.7	22%	0.217	56%	0.557	C	S	.	*	T	Hydrogen-bonded Turn	trans	-62.9	-14.4	179.4	-81.4	-179.2	173	-174.3	0	113.7	L379 N382 Q394 I407 D413	L379-K396 PolarHBondContact O-NZ 3.43Å; N382-K396 HydrophobicContact CB-CB 4.27Å; N382-K396 HydrophobicContact CB-CD 4.19Å; Q394-K396 VanDerWaalsContact C-N 3.31Å; Q394-K396 PolarHBondContact O-N 3.45Å; K396-I407 HydrophobicContact CB-CD1 4.29Å; K396-I407 HydrophobicContact CD-CG2 3.62Å; K396-I407 VanDerWaalsContact CE-CG2 3.41Å; K396-I407 HydrophobicContact CG-CG2 3.87Å; K396-D413 IonicContact NZ-OD2 2.8Å; K396-D413 PolarHBondContact NZ-OD2 3.04Å
397	H	44.1	Very low	50.7	Low	112 Å²	112	103.8 Å²	103.8	52%	0.519	56%	0.556	S	S	.	*			trans	-99.5	56.8	175.3	-67.2	-61.6	0	0	0	114.2	Q394 V395 H399	Q394-H397 PolarHBondContact O-N 2.86Å; V395-H397 PolarHBondContact O-N 3.16Å; V395-H397 VanDerWaalsContact O-N 3.08Å; H397-H399 PolarHBondContact O-N 3.18Å
398	R	39.8	Very low	51.7	Low	200 Å²	200	102 Å²	102	76%	0.755	55%	0.552	S	S	*	*			trans	-87	96.2	153	-174.7	165.6	-75.9	-161.2	-0.6	109.1	E400	R398-E400 WeakPolarHBondContact CD-OE1 3.38Å; R398-E400 HydrophobicContact CG-CG 4.17Å; R398-E400 PolarHBondContact O-N 2.84Å
399	H	43.6	Very low	53.1	Low	180 Å²	180	97.3 Å²	97.3	83%	0.833	53%	0.526	S	S	*	.			trans	-74.1	60	180	-148.4	-58.2	0	0	0	111.5	H397	H397-H399 PolarHBondContact O-N 3.18Å
400	E	38.7	Very low	54.6	Low	145 Å²	145	97 Å²	97	68%	0.678	53%	0.526	S	S	*	.			trans	-67	136.4	167.7	-89.3	174.8	-157	0	0	109.7	R398 G402	R398-E400 WeakPolarHBondContact CD-OE1 3.38Å; R398-E400 HydrophobicContact CG-CG 4.17Å; R398-E400 PolarHBondContact O-N 2.84Å; E400-G402 PolarHBondContact O-N 3.46Å
401	S	41.4	Very low	56.4	Low	130 Å²	130	95.3 Å²	95.3	91%	0.909	52%	0.524	S	S	*	.	S	Bend	trans	-77	53.8	-167.1	36.5	0	0	0	0	113.5
402	G	48.1	Very low	58.1	Low	56 Å²	56	93.2 Å²	93.2	58%	0.577	50%	0.504	S	S	*	.			trans	-98.1	147.8	171.1	0	0	0	0	0	112.5	E400 C404	E400-G402 PolarHBondContact O-N 3.46Å; G402-C404 PolarHBondContact O-N 3.39Å; G402-C404 VanDerWaalsContact O-N 3.11Å
403	L	50.6	Low	60	Low	174 Å²	174	85.1 Å²	85.1	91%	0.911	47%	0.466	S	S	*	.	S	Bend	trans	-67.1	-6.6	175.5	-135.6	79.8	0	0	0	113.8
404	C	53.6	Low	62.1	Low	49 Å²	49	84 Å²	84	33%	0.331	46%	0.46	S	S	.	.			trans	-141.9	118.6	-175.3	-130.3	0	0	0	0	109.7	R153 G402	R153-C404 VanDerWaalsContact CA-SG 3.52Å; R153-C404 HydrophobicContact CB-CB 4.31Å; R153-C404 PolarHBondContact O-SG 2.97Å; G402-C404 PolarHBondContact O-N 3.39Å; G402-C404 VanDerWaalsContact O-N 3.11Å
405	Y	64.3	Low	64.5	Low	90 Å²	90	83.4 Å²	83.4	35%	0.353	46%	0.458	S	S	.	.			trans	-91.8	141.6	166.8	54.8	-83.8	0	0	0	108.7	D156 K381	D156-Y405 PolarHBondContact OD1-OH 2.85Å; K381-Y405 HydrophobicContact CD-CE2 4.14Å; K381-Y405 WeakPolarHBondContact CE-OH 3.23Å; K381-Y405 HydrophobicContact CG-CE2 3.89Å; K381-Y405 PolarHBondContact NZ-OH 3.36Å
406	C	68.9	Low	66.8	Low	76 Å²	76	78.7 Å²	78.7	51%	0.514	43%	0.429	S	S	.	.			trans	-130.7	114.1	177	162.5	0	0	0	0	107.8	C150	C150-C406 HydrophobicContact CB-CB 4Å; C150-C406 WeakPolarHBondContact CB-SG 3.5Å; C150-C406 WeakPolarHBondContact SG-CA 3.4Å; C150-C406 WeakPolarHBondContact SG-CB 3.14Å; C150-C406 CovalentContact SG-SG 2.03Å; C150-C406 PolarHBondContact SG-SG 3.31Å
407	I	73.3	Confident	68.9	Low	28 Å²	28	76.6 Å²	76.6	14%	0.144	42%	0.421	C	S	.	.			trans	-134.6	106.7	-178	-58.7	179.3	0	0	0	107.2	K396	K396-I407 HydrophobicContact CB-CD1 4.29Å; K396-I407 HydrophobicContact CD-CG2 3.62Å; K396-I407 VanDerWaalsContact CE-CG2 3.41Å; K396-I407 HydrophobicContact CG-CG2 3.87Å
408	P	76.8	Confident	71.3	Confident	77 Å²	77	72.8 Å²	72.8	50%	0.5	40%	0.404	S	S	.	.	P	Polyproline II helix	trans	-70.9	159.1	175	30.2	-34.5	0	0	0	111
409	F	84.5	Confident	73.9	Confident	13 Å²	13	67.3 Å²	67.3	6%	0.057	39%	0.389	C	S	.	.	P	Polyproline II helix	trans	-68.2	132.1	174.7	-78.8	-45.6	0	0	0	112.1	P146 S376 L379 E380 D413 Y414 L417	P146-F409 HydrophobicContact CG-CD2 3.76Å; P146-F409 HydrophobicContact CG-CE2 3.58Å; P146-F409 HydrophobicContact CG-CG 4.47Å; P146-F409 HydrophobicContact CG-CZ 4.14Å; S376-F409 WeakPolarHBondContact O-CE1 3.38Å; L379-F409 HydrophobicContact CB-CE1 3.92Å; E380-F409 HydrophobicContact CB-CE1 3.87Å; E380-F409 HydrophobicContact CB-CZ 4.32Å; F409-D413 HydrophobicContact CB-CB 4.2Å; F409-D413 HydrophobicContact CD1-CB 3.65Å; F409-D413 HydrophobicContact CE1-CB 4.43Å; F409-D413 HydrophobicContact CG-CB 4.23Å; F409-Y414 HydrophobicContact CB-CD2 3.94Å; F409-Y414 HydrophobicContact CB-CE2 3.41Å; F409-Y414 VanDerWaalsContact CB-CE2 3.41Å; F409-Y414 HydrophobicContact CD2-CE1 4.27Å; F409-Y414 HydrophobicContact CG-CE2 4.42Å; F409-L417 HydrophobicContact CE2-CD1 4.32Å; F409-L417 HydrophobicContact CZ-CD1 4.3Å
410	G	84.1	Confident	76.3	Confident	25 Å²	25	58.8 Å²	58.8	26%	0.258	35%	0.349	S	S	.	.	P	Polyproline II helix	trans	-76.4	164.3	167.2	0	0	0	0	0	112.1	S412 D413 Y414	G410-S412 PolarHBondContact O-N 2.88Å; G410-D413 PolarHBondContact N-OD2 3.01Å; G410-D413 WeakPolarHBondContact O-CB 3.18Å; G410-D413 PolarHBondContact O-N 2.88Å; G410-Y414 VanDerWaalsContact O-CD2 3.3Å; G410-Y414 WeakPolarHBondContact O-CD2 3.29Å; G410-Y414 PolarHBondContact O-N 3.28Å
411	S	86.1	Confident	78.9	Confident	84 Å²	84	51.9 Å²	51.9	59%	0.587	32%	0.317	S	S	*	.	H	α-helix	trans	-59.2	-34.7	174.6	52.9	0	0	0	0	112.6	D413 Q415	S411-D413 VanDerWaalsContact C-N 3.28Å; S411-D413 PolarHBondContact O-N 3.42Å; S411-Q415 VanDerWaalsContact O-CG 3.3Å; S411-Q415 WeakPolarHBondContact O-CG 3.36Å; S411-Q415 PolarHBondContact O-N 3.17Å
412	S	86.8	Confident	81.4	Confident	42 Å²	42	49.6 Å²	49.6	29%	0.294	29%	0.294	S	S	.	.	H	α-helix	trans	-56.9	-39.1	170.6	50.1	0	0	0	0	113.4	G410 Q415 T416	G410-S412 PolarHBondContact O-N 2.88Å; S412-Q415 PolarHBondContact O-N 3.35Å; S412-T416 PolarHBondContact O-N 2.88Å; S412-T416 PolarHBondContact O-OG1 3.04Å
413	D	89.9	Confident	83.5	Confident	1 Å²	1	47 Å²	47	1%	0.005	27%	0.267	C	S	.	.	H	α-helix	trans	-74.5	-44.5	-172.1	-49.4	-12.1	0	0	0	108.4	L379 K396 F409 G410 S411 Q415 T416 L417	L379-D413 HydrophobicContact CB-CB 4.31Å; L379-D413 HydrophobicContact CD2-CB 4.4Å; K396-D413 IonicContact NZ-OD2 2.8Å; K396-D413 PolarHBondContact NZ-OD2 3.04Å; F409-D413 HydrophobicContact CB-CB 4.2Å; F409-D413 HydrophobicContact CD1-CB 3.65Å; F409-D413 HydrophobicContact CE1-CB 4.43Å; F409-D413 HydrophobicContact CG-CB 4.23Å; G410-D413 PolarHBondContact N-OD2 3.01Å; G410-D413 WeakPolarHBondContact O-CB 3.18Å; G410-D413 PolarHBondContact O-N 2.88Å; S411-D413 VanDerWaalsContact C-N 3.28Å; S411-D413 PolarHBondContact O-N 3.42Å; D413-Q415 PolarHBondContact O-N 3.47Å; D413-T416 PolarHBondContact O-N 2.71Å; D413-L417 WeakPolarHBondContact O-CG 3.28Å; D413-L417 PolarHBondContact O-N 3.06Å
414	Y	92.4	Very high	85.4	Confident	3 Å²	3	38.9 Å²	38.9	1%	0.012	22%	0.224	C	C	.	.	H	α-helix	trans	-58.4	-43.4	168.9	-74.1	-70.4	0	0	0	112.6	V143 I262 M266 F409 G410 T416 L417 L418	V143-Y414 HydrophobicContact CG1-CE1 4.06Å; I262-Y414 HydrophobicContact CG2-CD1 4.07Å; M266-Y414 HydrophobicContact CB-CD1 3.95Å; M266-Y414 HydrophobicContact CB-CD2 4.09Å; M266-Y414 HydrophobicContact CB-CG 3.68Å; M266-Y414 HydrophobicContact CG-CD2 4.14Å; M266-Y414 HydrophobicContact CG-CG 3.97Å; F409-Y414 HydrophobicContact CB-CD2 3.94Å; F409-Y414 HydrophobicContact CB-CE2 3.41Å; F409-Y414 VanDerWaalsContact CB-CE2 3.41Å; F409-Y414 HydrophobicContact CD2-CE1 4.27Å; F409-Y414 HydrophobicContact CG-CE2 4.42Å; G410-Y414 VanDerWaalsContact O-CD2 3.3Å; G410-Y414 WeakPolarHBondContact O-CD2 3.29Å; G410-Y414 PolarHBondContact O-N 3.28Å; Y414-T416 VanDerWaalsContact C-N 3.34Å; Y414-T416 PolarHBondContact O-N 2.8Å; Y414-L417 PolarHBondContact O-N 3.08Å; Y414-L418 WeakPolarHBondContact O-CB 3.24Å; Y414-L418 VanDerWaalsContact O-CG 3.3Å; Y414-L418 WeakPolarHBondContact O-CG 3.29Å; Y414-L418 PolarHBondContact O-N 3.39Å
415	Q	93	Very high	87.1	Confident	108 Å²	108	38.1 Å²	38.1	51%	0.505	22%	0.218	S	C	.	.	H	α-helix	trans	-62.1	-40	176.6	-74.9	174.2	7.9	0	0	112.3	S411 S412 D413 L418 I419	S411-Q415 VanDerWaalsContact O-CG 3.3Å; S411-Q415 WeakPolarHBondContact O-CG 3.36Å; S411-Q415 PolarHBondContact O-N 3.17Å; S412-Q415 PolarHBondContact O-N 3.35Å; D413-Q415 PolarHBondContact O-N 3.47Å; Q415-L418 PolarHBondContact O-N 3.18Å; Q415-I419 WeakPolarHBondContact O-CB 3.47Å; Q415-I419 VanDerWaalsContact O-CG1 3.28Å; Q415-I419 WeakPolarHBondContact O-CG1 3.32Å; Q415-I419 PolarHBondContact O-N 3.38Å
416	T	92.8	Very high	88.2	Confident	10 Å²	10	36.1 Å²	36.1	6%	0.061	22%	0.22	C	C	.	.	H	α-helix	trans	-64.4	-41.6	175.5	-61.2	0	0	0	0	111.8	L379 S412 D413 Y414 S420 F467 T468 L471	L379-T416 HydrophobicContact CD1-CG2 4.02Å; L379-T416 HydrophobicContact CD2-CG2 4.19Å; S412-T416 PolarHBondContact O-N 2.88Å; S412-T416 PolarHBondContact O-OG1 3.04Å; D413-T416 PolarHBondContact O-N 2.71Å; Y414-T416 VanDerWaalsContact C-N 3.34Å; Y414-T416 PolarHBondContact O-N 2.8Å; T416-S420 VanDerWaalsContact O-CB 3.28Å; T416-S420 WeakPolarHBondContact O-CB 3.48Å; T416-S420 PolarHBondContact O-N 3.06Å; T416-S420 PolarHBondContact O-OG 3.23Å; T416-F467 HydrophobicContact CG2-CD1 4.32Å; T416-F467 HydrophobicContact CG2-CE1 4.29Å; T416-T468 HydrophobicContact CG2-CG2 4.23Å; T416-T468 WeakPolarHBondContact CG2-OG1 3.46Å; T416-L471 HydrophobicContact CG2-CD1 4.04Å
417	L	93.4	Very high	89.1	Confident	6 Å²	6	34.6 Å²	34.6	3%	0.031	21%	0.207	C	C	.	.	H	α-helix	trans	-67.1	-37.6	174.6	-67.8	174.5	0	0	0	112.5	I262 L379 F409 D413 Y414 S420 S421	I262-L417 HydrophobicContact CD1-CB 4.09Å; I262-L417 HydrophobicContact CG2-CB 3.91Å; L379-L417 HydrophobicContact CD1-CD1 4.39Å; L379-L417 HydrophobicContact CD1-CD2 3.82Å; L379-L417 HydrophobicContact CD1-CG 3.74Å; F409-L417 HydrophobicContact CE2-CD1 4.32Å; F409-L417 HydrophobicContact CZ-CD1 4.3Å; D413-L417 WeakPolarHBondContact O-CG 3.28Å; D413-L417 PolarHBondContact O-N 3.06Å; Y414-L417 PolarHBondContact O-N 3.08Å; L417-S420 PolarHBondContact O-OG 3.01Å; L417-S421 PolarHBondContact O-N 3.39Å; L417-S421 PolarHBondContact O-OG 3.49Å
418	L	95.1	Very high	89.6	Confident	32 Å²	32	34.2 Å²	34.2	17%	0.168	21%	0.206	C	C	.	.	H	α-helix	trans	-61.8	-57.6	173.2	-74.6	173.7	0	0	0	110.8	M259 I262 L263 M266 Y414 Q415 S420 S421	M259-L418 VanDerWaalsContact CE-CA 3.5Å; M259-L418 HydrophobicContact CE-CB 4.41Å; M259-L418 HydrophobicContact CE-CD2 3.87Å; M259-L418 VanDerWaalsContact CE-O 3.26Å; M259-L418 WeakPolarHBondContact CE-O 3.42Å; M259-L418 HydrophobicContact SD-CB 4.42Å; M259-L418 HydrophobicContact SD-CD2 3.88Å; I262-L418 HydrophobicContact CB-CD2 3.94Å; I262-L418 HydrophobicContact CB-CG 4.5Å; I262-L418 HydrophobicContact CG2-CD2 3.7Å; I262-L418 HydrophobicContact CG2-CG 3.71Å; L263-L418 HydrophobicContact CB-CD2 4.43Å; M266-L418 HydrophobicContact CE-CD1 4.14Å; M266-L418 HydrophobicContact SD-CD1 4.18Å; Y414-L418 WeakPolarHBondContact O-CB 3.24Å; Y414-L418 VanDerWaalsContact O-CG 3.3Å; Y414-L418 WeakPolarHBondContact O-CG 3.29Å; Y414-L418 PolarHBondContact O-N 3.39Å; Q415-L418 PolarHBondContact O-N 3.18Å; L418-S420 PolarHBondContact O-N 3.35Å; L418-S421 PolarHBondContact O-N 2.92Å
419	I	94.7	Very high	90.1	Very high	85 Å²	85	34.7 Å²	34.7	44%	0.436	21%	0.209	S	C	.	.	H	α-helix	trans	-59.3	-48.2	-177.4	-66.3	164	0	0	0	110.4	Q415 S421 L422 T468 F472	Q415-I419 WeakPolarHBondContact O-CB 3.47Å; Q415-I419 VanDerWaalsContact O-CG1 3.28Å; Q415-I419 WeakPolarHBondContact O-CG1 3.32Å; Q415-I419 PolarHBondContact O-N 3.38Å; I419-S421 VanDerWaalsContact C-N 3.34Å; I419-S421 PolarHBondContact O-N 3.22Å; I419-L422 WeakPolarHBondContact O-CB 3.28Å; I419-L422 PolarHBondContact O-N 2.98Å; I419-T468 HydrophobicContact CB-CG2 3.84Å; I419-T468 HydrophobicContact CD1-CG2 4.36Å; I419-T468 HydrophobicContact CG2-CG2 3.57Å; I419-F472 WeakPolarHBondContact O-CD2 3.25Å
420	S	94.4	Very high	90.3	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-62.1	-36.3	-176.1	58.1	0	0	0	0	113.6	T416 L417 L418 L422 G423	T416-S420 VanDerWaalsContact O-CB 3.28Å; T416-S420 WeakPolarHBondContact O-CB 3.48Å; T416-S420 PolarHBondContact O-N 3.06Å; T416-S420 PolarHBondContact O-OG 3.23Å; L417-S420 PolarHBondContact O-OG 3.01Å; L418-S420 PolarHBondContact O-N 3.35Å; S420-L422 VanDerWaalsContact C-N 3.31Å; S420-L422 PolarHBondContact O-N 3.17Å; S420-G423 PolarHBondContact O-N 3.11Å; S420-G423 VanDerWaalsContact O-N 3.09Å
421	S	93.4	Very high	90.3	Very high	0 Å²	0	37.5 Å²	37.5	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-76.4	-15.7	-178.5	-35.3	0	0	0	0	113.8	L417 L418 I419 G423 E424	L417-S421 PolarHBondContact O-N 3.39Å; L417-S421 PolarHBondContact O-OG 3.49Å; L418-S421 PolarHBondContact O-N 2.92Å; I419-S421 VanDerWaalsContact C-N 3.34Å; I419-S421 PolarHBondContact O-N 3.22Å; S421-G423 PolarHBondContact O-N 3.07Å; S421-E424 WeakPolarHBondContact O-CB 3.27Å; S421-E424 WeakPolarHBondContact O-CG 3.37Å; S421-E424 PolarHBondContact O-N 3.03Å
422	L	93.4	Very high	90.2	Very high	83 Å²	83	37.5 Å²	37.5	44%	0.435	21%	0.21	S	C	.	.	H	α-helix	trans	-57.7	-26.1	165.7	-62.8	174	0	0	0	111.7	M255 M259 I419 S420 E424 V425 A426 F472	M255-L422 HydrophobicContact SD-CD2 4.2Å; M259-L422 HydrophobicContact SD-CD2 4.12Å; M259-L422 HydrophobicContact SD-CG 4.37Å; I419-L422 WeakPolarHBondContact O-CB 3.28Å; I419-L422 PolarHBondContact O-N 2.98Å; S420-L422 VanDerWaalsContact C-N 3.31Å; S420-L422 PolarHBondContact O-N 3.17Å; L422-E424 PolarHBondContact O-N 3.33Å; L422-V425 PolarHBondContact O-N 3.2Å; L422-A426 PolarHBondContact O-N 3.1Å; L422-A426 VanDerWaalsContact O-N 3.13Å; L422-F472 HydrophobicContact CB-CE2 4.03Å
423	G	91.5	Very high	90.2	Very high	0 Å²	0	39.6 Å²	39.6	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-56.3	-29.7	173.4	0	0	0	0	0	113.4	S420 S421 V425 A426 F472 S476	S420-G423 PolarHBondContact O-N 3.11Å; S420-G423 VanDerWaalsContact O-N 3.09Å; S421-G423 PolarHBondContact O-N 3.07Å; G423-V425 PolarHBondContact O-N 2.82Å; G423-V425 VanDerWaalsContact O-N 3.12Å; G423-A426 PolarHBondContact O-N 3.38Å; G423-F472 VanDerWaalsContact N-CE2 3.31Å; G423-S476 WeakPolarHBondContact O-CA 3.24Å; G423-S476 WeakPolarHBondContact O-CB 3.37Å; G423-S476 PolarHBondContact O-OG 2.98Å
424	E	91.1	Very high	90	Very high	5 Å²	5	41.1 Å²	41.1	2%	0.023	23%	0.229	C	C	.	.	H	α-helix	trans	-58.7	-28	-179.2	-65.9	-174.9	163.9	0	0	113.5	M255 S258 Y368 S421 L422 R475 S479	M255-E424 HydrophobicContact CB-CB 4.42Å; M255-E424 HydrophobicContact CG-CB 4.39Å; S258-E424 PolarHBondContact OG-OE2 3.45Å; Y368-E424 WeakPolarHBondContact CE2-OE1 3.33Å; Y368-E424 PolarHBondContact OH-OE1 2.93Å; S421-E424 WeakPolarHBondContact O-CB 3.27Å; S421-E424 WeakPolarHBondContact O-CG 3.37Å; S421-E424 PolarHBondContact O-N 3.03Å; L422-E424 PolarHBondContact O-N 3.33Å; E424-R475 HydrophobicContact CG-CB 4.42Å; E424-R475 IonicContact OE1-CZ 3.71Å; E424-R475 IonicContact OE1-NE 2.75Å; E424-R475 PolarHBondContact OE1-NE 3.39Å; E424-R475 IonicContact OE1-NH2 3.81Å; E424-R475 PolarHBondContact OE1-NH2 2.68Å; E424-S479 WeakPolarHBondContact O-CB 3.35Å; E424-S479 PolarHBondContact O-OG 3.18Å
425	V	89	Confident	89.6	Confident	32 Å²	32	41.4 Å²	41.4	19%	0.194	23%	0.231	C	C	.	.	H	α-helix	trans	-109.1	-31.7	179.7	174.2	0	0	0	0	112.3	I252 M255 L422 G423 L427 V428	I252-V425 HydrophobicContact CG1-CG1 4.08Å; I252-V425 HydrophobicContact CG1-CG2 4.32Å; M255-V425 HydrophobicContact CB-CG2 3.55Å; M255-V425 HydrophobicContact CG-CG2 3.86Å; M255-V425 HydrophobicContact SD-CB 3.92Å; M255-V425 HydrophobicContact SD-CG2 3.61Å; L422-V425 PolarHBondContact O-N 3.2Å; G423-V425 PolarHBondContact O-N 2.82Å; G423-V425 VanDerWaalsContact O-N 3.12Å; V425-L427 VanDerWaalsContact C-N 3.32Å; V425-L427 PolarHBondContact O-N 3.21Å; V425-L427 VanDerWaalsContact O-N 3.14Å; V425-V428 WeakPolarHBondContact O-CB 3.14Å; V425-V428 WeakPolarHBondContact O-CG2 3.48Å; V425-V428 PolarHBondContact O-N 3.47Å
426	A	88.1	Confident	89	Confident	49 Å²	49	40.9 Å²	40.9	41%	0.405	23%	0.232	S	C	.	.	H	α-helix	trans	-52.8	-41.2	-169.3	0	0	0	0	0	114.9	L422 G423 F472	L422-A426 PolarHBondContact O-N 3.1Å; L422-A426 VanDerWaalsContact O-N 3.13Å; G423-A426 PolarHBondContact O-N 3.38Å; A426-F472 HydrophobicContact CB-CE1 4.2Å; A426-F472 HydrophobicContact CB-CE2 4.2Å; A426-F472 HydrophobicContact CB-CZ 3.45Å; A426-F472 VanDerWaalsContact CB-CZ 3.45Å
427	L	87.4	Confident	88.7	Confident	44 Å²	44	44 Å²	44	23%	0.23	25%	0.251	C	S	.	.	T	Hydrogen-bonded Turn	trans	-99.6	13	179.6	-52.9	-177.1	0	0	0	114	V425 L430 N431 S476 M480	V425-L427 VanDerWaalsContact C-N 3.32Å; V425-L427 PolarHBondContact O-N 3.21Å; V425-L427 VanDerWaalsContact O-N 3.14Å; L427-L430 HydrophobicContact CB-CB 4.31Å; L427-L430 HydrophobicContact CB-CD2 4.41Å; L427-L430 HydrophobicContact CD1-CD2 4.43Å; L427-L430 HydrophobicContact CD2-CD2 4.16Å; L427-L430 WeakPolarHBondContact O-CB 3.23Å; L427-L430 PolarHBondContact O-N 3.41Å; L427-N431 PolarHBondContact O-N 3.31Å; L427-S476 VanDerWaalsContact CB-OG 3.25Å; L427-S476 WeakPolarHBondContact CB-OG 3.34Å; L427-S476 WeakPolarHBondContact CD1-OG 3.17Å; L427-S476 WeakPolarHBondContact CG-OG 3.08Å; L427-M480 HydrophobicContact CB-CE 4.45Å; L427-M480 HydrophobicContact CB-CG 4.5Å; L427-M480 HydrophobicContact CB-SD 3.64Å; L427-M480 HydrophobicContact CD1-SD 4.3Å
428	V	84.6	Confident	88.4	Confident	19 Å²	19	49 Å²	49	12%	0.115	27%	0.272	C	S	.	.	H	α-helix	trans	-60.5	-42.2	174	172.9	0	0	0	0	112.6	V425 L430 N431 I432	V425-V428 WeakPolarHBondContact O-CB 3.14Å; V425-V428 WeakPolarHBondContact O-CG2 3.48Å; V425-V428 PolarHBondContact O-N 3.47Å; V428-L430 VanDerWaalsContact C-N 3.33Å; V428-L430 PolarHBondContact O-N 3.38Å; V428-N431 VanDerWaalsContact O-CB 3.29Å; V428-N431 WeakPolarHBondContact O-CB 2.94Å; V428-N431 PolarHBondContact O-N 3.4Å; V428-N431 VanDerWaalsContact O-N 3.16Å; V428-I432 PolarHBondContact O-N 2.94Å; V428-I432 VanDerWaalsContact O-N 3.15Å
429	P	86.6	Confident	87.9	Confident	87 Å²	87	47.5 Å²	47.5	57%	0.565	26%	0.264	S	S	*	.	H	α-helix	trans	-61.3	-40.4	173.9	-23.8	35.3	0	0	0	112.6	N431 I432 V433	P429-N431 VanDerWaalsContact C-N 3.3Å; P429-N431 PolarHBondContact O-N 2.65Å; P429-I432 PolarHBondContact O-N 2.98Å; P429-V433 PolarHBondContact O-N 3.4Å
430	L	87.7	Confident	87.6	Confident	93 Å²	93	45 Å²	45	49%	0.487	25%	0.25	S	C	.	.	H	α-helix	trans	-61.9	-38.3	174.9	179.3	63.1	0	0	0	111.3	L427 V428 I432 V433 L434	L427-L430 HydrophobicContact CB-CB 4.31Å; L427-L430 HydrophobicContact CB-CD2 4.41Å; L427-L430 HydrophobicContact CD1-CD2 4.43Å; L427-L430 HydrophobicContact CD2-CD2 4.16Å; L427-L430 WeakPolarHBondContact O-CB 3.23Å; L427-L430 PolarHBondContact O-N 3.41Å; V428-L430 VanDerWaalsContact C-N 3.33Å; V428-L430 PolarHBondContact O-N 3.38Å; L430-I432 PolarHBondContact O-N 2.92Å; L430-V433 PolarHBondContact O-N 3.39Å; L430-L434 WeakPolarHBondContact O-CB 3.48Å; L430-L434 PolarHBondContact O-N 3.33Å
431	N	85.8	Confident	87.5	Confident	4 Å²	4	48.4 Å²	48.4	2%	0.021	26%	0.262	C	S	.	.	H	α-helix	trans	-60.7	-44	175.6	-158.1	17.1	0	0	0	111.8	L427 V428 P429 V433 L434 L435 M480 V484	L427-N431 PolarHBondContact O-N 3.31Å; V428-N431 VanDerWaalsContact O-CB 3.29Å; V428-N431 WeakPolarHBondContact O-CB 2.94Å; V428-N431 PolarHBondContact O-N 3.4Å; V428-N431 VanDerWaalsContact O-N 3.16Å; P429-N431 VanDerWaalsContact C-N 3.3Å; P429-N431 PolarHBondContact O-N 2.65Å; N431-V433 VanDerWaalsContact C-N 3.34Å; N431-V433 PolarHBondContact O-N 3.42Å; N431-L434 WeakPolarHBondContact O-CB 3.34Å; N431-L434 PolarHBondContact O-N 3.24Å; N431-L435 VanDerWaalsContact O-CG 3.23Å; N431-L435 WeakPolarHBondContact O-CG 3.45Å; N431-L435 PolarHBondContact O-N 3.46Å; N431-M480 HydrophobicContact CB-CB 4.48Å; N431-M480 HydrophobicContact CB-CE 3.6Å; N431-M480 HydrophobicContact CB-CG 4.03Å; N431-M480 WeakPolarHBondContact ND2-CA 3.26Å; N431-M480 PolarHBondContact ND2-O 3.39Å; N431-V484 WeakPolarHBondContact OD1-CG2 3.32Å
432	I	83.2	Confident	87.3	Confident	84 Å²	84	52.6 Å²	52.6	43%	0.431	28%	0.284	S	S	.	.	H	α-helix	trans	-61.8	-42.8	177.9	-63.4	168.7	0	0	0	110.7	V428 P429 L430 N436	V428-I432 PolarHBondContact O-N 2.94Å; V428-I432 VanDerWaalsContact O-N 3.15Å; P429-I432 PolarHBondContact O-N 2.98Å; L430-I432 PolarHBondContact O-N 2.92Å; I432-N436 VanDerWaalsContact O-CG 3.31Å; I432-N436 PolarHBondContact O-N 3.37Å; I432-N436 PolarHBondContact O-ND2 3.13Å
433	V	85.9	Confident	87.3	Confident	86 Å²	86	48.7 Å²	48.7	52%	0.521	26%	0.263	S	S	.	.	H	α-helix	trans	-62.5	-47.4	174.9	176.5	0	0	0	0	110.9	P429 L430 N431 L435 N436 V437	P429-V433 PolarHBondContact O-N 3.4Å; L430-V433 PolarHBondContact O-N 3.39Å; N431-V433 VanDerWaalsContact C-N 3.34Å; N431-V433 PolarHBondContact O-N 3.42Å; V433-L435 VanDerWaalsContact C-N 3.33Å; V433-L435 PolarHBondContact O-N 3.17Å; V433-N436 PolarHBondContact O-N 2.94Å; V433-N436 VanDerWaalsContact O-N 3.13Å; V433-V437 HydrophobicContact CG1-CG2 4.24Å; V433-V437 WeakPolarHBondContact O-CG2 3.35Å; V433-V437 PolarHBondContact O-N 3.04Å
434	L	85.8	Confident	87.3	Confident	33 Å²	33	48.7 Å²	48.7	17%	0.173	26%	0.263	C	S	.	.	H	α-helix	trans	-56.4	-46.1	179.5	-163.9	78.9	0	0	0	111.7	L430 N431 N436 V437 F438 L447	L430-L434 WeakPolarHBondContact O-CB 3.48Å; L430-L434 PolarHBondContact O-N 3.33Å; N431-L434 WeakPolarHBondContact O-CB 3.34Å; N431-L434 PolarHBondContact O-N 3.24Å; L434-N436 VanDerWaalsContact C-N 3.3Å; L434-N436 PolarHBondContact O-N 3.1Å; L434-V437 PolarHBondContact O-N 3.12Å; L434-F438 HydrophobicContact CD1-CD2 3.53Å; L434-F438 HydrophobicContact CD1-CE2 3.79Å; L434-F438 HydrophobicContact CG-CD2 4.08Å; L434-F438 PolarHBondContact O-N 2.74Å; L434-L447 HydrophobicContact CD2-CD1 4.11Å; L434-L447 HydrophobicContact CD2-CD2 4.1Å; L434-L447 HydrophobicContact CD2-CG 4Å
435	L	84.1	Confident	87.5	Confident	9 Å²	9	49.1 Å²	49.1	5%	0.047	27%	0.266	C	S	.	.	H	α-helix	trans	-64.5	-31.2	178.7	-69.5	171	0	0	0	114.1	N431 V433 G439 R440 V484 I487	N431-L435 VanDerWaalsContact O-CG 3.23Å; N431-L435 WeakPolarHBondContact O-CG 3.45Å; N431-L435 PolarHBondContact O-N 3.46Å; V433-L435 VanDerWaalsContact C-N 3.33Å; V433-L435 PolarHBondContact O-N 3.17Å; L435-G439 WeakPolarHBondContact O-CA 3.24Å; L435-G439 PolarHBondContact O-N 3.2Å; L435-R440 HydrophobicContact CD2-CG 4.1Å; L435-R440 PolarHBondContact O-NH1 3.16Å; L435-V484 HydrophobicContact CD1-CG2 4.18Å; L435-V484 HydrophobicContact CD2-CB 4.19Å; L435-V484 HydrophobicContact CD2-CG1 3.46Å; L435-V484 VanDerWaalsContact CD2-CG1 3.46Å; L435-V484 HydrophobicContact CD2-CG2 3.72Å; L435-V484 HydrophobicContact CG-CG2 4.22Å; L435-I487 HydrophobicContact CD1-CD1 3.98Å
436	N	82	Confident	87.8	Confident	98 Å²	98	50.7 Å²	50.7	52%	0.524	28%	0.276	S	S	.	.	H	α-helix	trans	-80.5	-30.4	178	-72.3	-21	0	0	0	112.4	I432 V433 L434 R554	I432-N436 VanDerWaalsContact O-CG 3.31Å; I432-N436 PolarHBondContact O-N 3.37Å; I432-N436 PolarHBondContact O-ND2 3.13Å; V433-N436 PolarHBondContact O-N 2.94Å; V433-N436 VanDerWaalsContact O-N 3.13Å; L434-N436 VanDerWaalsContact C-N 3.3Å; L434-N436 PolarHBondContact O-N 3.1Å; N436-R554 VanDerWaalsContact O-CZ 3.24Å; N436-R554 PolarHBondContact O-NE 2.92Å; N436-R554 VanDerWaalsContact O-NE 3.17Å; N436-R554 PolarHBondContact O-NH2 2.79Å
437	V	85.9	Confident	88.1	Confident	75 Å²	75	48.6 Å²	48.6	46%	0.455	26%	0.258	S	S	.	.	H	α-helix	trans	-90	-45.8	-177.8	175.6	0	0	0	0	113	V433 L434 R554	V433-V437 HydrophobicContact CG1-CG2 4.24Å; V433-V437 WeakPolarHBondContact O-CG2 3.35Å; V433-V437 PolarHBondContact O-N 3.04Å; L434-V437 PolarHBondContact O-N 3.12Å; V437-R554 PolarHBondContact O-NH1 2.96Å; V437-R554 PolarHBondContact O-NH2 3.16Å
438	F	85.7	Confident	88.5	Confident	111 Å²	111	46.5 Å²	46.5	49%	0.487	25%	0.247	S	C	.	.	T	Hydrogen-bonded Turn	trans	-104.2	-10.1	-173.2	-62.8	-79.2	0	0	0	114.2	L434 I442	L434-F438 HydrophobicContact CD1-CD2 3.53Å; L434-F438 HydrophobicContact CD1-CE2 3.79Å; L434-F438 HydrophobicContact CG-CD2 4.08Å; L434-F438 PolarHBondContact O-N 2.74Å; F438-I442 HydrophobicContact CB-CB 4.34Å; F438-I442 HydrophobicContact CB-CG2 4.22Å
439	G	86.5	Confident	89	Confident	0 Å²	0	49.5 Å²	49.5	0%	0	26%	0.262	C	S	.	.			trans	77.5	179.1	-172	0	0	0	0	0	112.7	L435 S443	L435-G439 WeakPolarHBondContact O-CA 3.24Å; L435-G439 PolarHBondContact O-N 3.2Å; G439-S443 VanDerWaalsContact O-CB 3.3Å; G439-S443 WeakPolarHBondContact O-CB 3.3Å; G439-S443 PolarHBondContact O-N 2.99Å; G439-S443 PolarHBondContact O-OG 2.77Å
440	R	88	Confident	89.5	Confident	34 Å²	34	49 Å²	49	13%	0.128	25%	0.254	C	S	.	.	H	α-helix	trans	-82.1	-43.1	-167.8	-73.2	62.9	164.5	141.2	-1.1	111.7	L435 S443 L444 V484 Y488 E491 E552 T553	L435-R440 HydrophobicContact CD2-CG 4.1Å; L435-R440 PolarHBondContact O-NH1 3.16Å; R440-S443 PolarHBondContact O-N 3.4Å; R440-L444 WeakPolarHBondContact O-CB 3.48Å; R440-L444 WeakPolarHBondContact O-CG 3.47Å; R440-L444 PolarHBondContact O-N 3.15Å; R440-V484 HydrophobicContact CB-CG1 4.47Å; R440-Y488 HydrophobicContact CB-CD2 3.57Å; R440-Y488 HydrophobicContact CB-CE2 4.39Å; R440-Y488 HydrophobicContact CB-CG 4.36Å; R440-Y488 HydrophobicContact CG-CD2 4.26Å; R440-E491 IonicContact CZ-OE1 3.27Å; R440-E491 IonicContact CZ-OE2 2.7Å; R440-E491 IonicContact NE-OE1 2.74Å; R440-E491 PolarHBondContact NE-OE1 2.7Å; R440-E491 IonicContact NE-OE2 3.19Å; R440-E491 PolarHBondContact NE-OE2 2.99Å; R440-E491 IonicContact NH2-OE1 3.63Å; R440-E491 PolarHBondContact NH2-OE1 3.38Å; R440-E491 IonicContact NH2-OE2 2.76Å; R440-E552 PolarHBondContact N-OE1 3.02Å; R440-E552 PolarHBondContact N-OE2 2.84Å; R440-T553 WeakPolarHBondContact CD-OG1 3.4Å; R440-T553 WeakPolarHBondContact CG-OG1 3.11Å
441	R	90.9	Very high	90	Very high	71 Å²	71	44.5 Å²	44.5	27%	0.268	23%	0.231	S	C	.	.	H	α-helix	trans	-65.8	-43.6	-175.3	-178.2	176.5	158.9	-159.6	-4	112.3	T445 N546 F547 L549 E552	R441-T445 PolarHBondContact O-N 3.19Å; R441-T445 VanDerWaalsContact O-N 3.12Å; R441-T445 PolarHBondContact O-OG1 3.09Å; R441-N546 WeakPolarHBondContact CG-O 3.3Å; R441-F547 PolarHBondContact NE-O 3.32Å; R441-F547 PolarHBondContact NH2-O 3.43Å; R441-L549 WeakPolarHBondContact CD-O 3.21Å; R441-L549 HydrophobicContact CG-CB 4.32Å; R441-L549 PolarHBondContact NE-O 2.75Å; R441-L549 PolarHBondContact NH1-O 3.2Å; R441-E552 WeakPolarHBondContact CB-OE2 3.2Å; R441-E552 PolarHBondContact N-OE2 3.03Å
442	I	91	Very high	90.5	Very high	87 Å²	87	44.7 Å²	44.7	45%	0.446	23%	0.232	S	C	.	.	H	α-helix	trans	-68.6	-45.4	177.6	-60.1	179.3	0	0	0	109.9	F438 L444 T445 V446	F438-I442 HydrophobicContact CB-CB 4.34Å; F438-I442 HydrophobicContact CB-CG2 4.22Å; I442-L444 PolarHBondContact O-N 3.27Å; I442-T445 WeakPolarHBondContact O-CB 3.41Å; I442-T445 PolarHBondContact O-N 3.42Å; I442-V446 HydrophobicContact CG2-CG2 4.17Å; I442-V446 WeakPolarHBondContact O-CG2 3.28Å; I442-V446 PolarHBondContact O-N 2.92Å
443	S	92.3	Very high	91.2	Very high	1 Å²	1	45.5 Å²	45.5	1%	0.007	24%	0.237	C	C	.	.	H	α-helix	trans	-55.8	-48.2	176	-60.9	0	0	0	0	112	G439 R440 T445 V446 L447	G439-S443 VanDerWaalsContact O-CB 3.3Å; G439-S443 WeakPolarHBondContact O-CB 3.3Å; G439-S443 PolarHBondContact O-N 2.99Å; G439-S443 PolarHBondContact O-OG 2.77Å; R440-S443 PolarHBondContact O-N 3.4Å; S443-T445 VanDerWaalsContact C-N 3.28Å; S443-T445 PolarHBondContact O-N 3.27Å; S443-V446 PolarHBondContact O-N 3.45Å; S443-L447 VanDerWaalsContact O-CB 3.28Å; S443-L447 WeakPolarHBondContact O-CB 3.46Å; S443-L447 WeakPolarHBondContact O-CG 3.5Å; S443-L447 PolarHBondContact O-N 3.44Å
444	L	92.2	Very high	91.6	Very high	0 Å²	0	42 Å²	42	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-58.8	-35.9	174.5	-77.4	172.5	0	0	0	113.5	R440 I442 Q448 V484 V485 Y488 N546 L549	R440-L444 WeakPolarHBondContact O-CB 3.48Å; R440-L444 WeakPolarHBondContact O-CG 3.47Å; R440-L444 PolarHBondContact O-N 3.15Å; I442-L444 PolarHBondContact O-N 3.27Å; L444-Q448 WeakPolarHBondContact O-CB 3.44Å; L444-Q448 PolarHBondContact O-N 2.98Å; L444-V484 HydrophobicContact CD1-CG1 4.2Å; L444-V484 HydrophobicContact CD2-CB 3.68Å; L444-V484 HydrophobicContact CD2-CG1 3.63Å; L444-V484 HydrophobicContact CG-CB 4.15Å; L444-V484 HydrophobicContact CG-CG1 3.53Å; L444-V485 HydrophobicContact CD2-CB 4.4Å; L444-V485 HydrophobicContact CD2-CG2 3.41Å; L444-V485 VanDerWaalsContact CD2-CG2 3.41Å; L444-Y488 HydrophobicContact CD1-CD1 4.32Å; L444-Y488 HydrophobicContact CD1-CG 4.16Å; L444-N546 HydrophobicContact CB-CB 4.13Å; L444-N546 PolarHBondContact O-ND2 3.44Å; L444-L549 HydrophobicContact CD1-CD1 4.48Å
445	T	94.4	Very high	92.1	Very high	15 Å²	15	40.5 Å²	40.5	9%	0.092	21%	0.208	C	C	.	.	H	α-helix	trans	-72.3	-48.8	-179.8	-55.4	0	0	0	0	110.4	R441 I442 S443 Q448 L449 A543 F547	R441-T445 PolarHBondContact O-N 3.19Å; R441-T445 VanDerWaalsContact O-N 3.12Å; R441-T445 PolarHBondContact O-OG1 3.09Å; I442-T445 WeakPolarHBondContact O-CB 3.41Å; I442-T445 PolarHBondContact O-N 3.42Å; S443-T445 VanDerWaalsContact C-N 3.28Å; S443-T445 PolarHBondContact O-N 3.27Å; T445-Q448 PolarHBondContact O-N 3.07Å; T445-L449 HydrophobicContact CG2-CD1 4.4Å; T445-L449 WeakPolarHBondContact O-CG 3.48Å; T445-L449 PolarHBondContact O-N 3.16Å; T445-L449 VanDerWaalsContact O-N 3.1Å; T445-A543 HydrophobicContact CG2-CB 4.32Å; T445-F547 HydrophobicContact CG2-CB 4.03Å; T445-F547 HydrophobicContact CG2-CD2 4.46Å; T445-F547 PolarHBondContact OG1-N 3.08Å
446	V	94.9	Very high	92.6	Very high	65 Å²	65	43.6 Å²	43.6	39%	0.394	22%	0.223	S	C	.	.	H	α-helix	trans	-67.5	-47.8	-177.5	174.2	0	0	0	0	111.6	I442 S443 Q448 L449 L450	I442-V446 HydrophobicContact CG2-CG2 4.17Å; I442-V446 WeakPolarHBondContact O-CG2 3.28Å; I442-V446 PolarHBondContact O-N 2.92Å; S443-V446 PolarHBondContact O-N 3.45Å; V446-Q448 VanDerWaalsContact C-N 3.25Å; V446-Q448 PolarHBondContact O-N 3.45Å; V446-L449 PolarHBondContact O-N 3.07Å; V446-L450 HydrophobicContact CG1-CD1 3.83Å; V446-L450 HydrophobicContact CG1-CG 4.31Å; V446-L450 WeakPolarHBondContact O-CG 3.45Å; V446-L450 PolarHBondContact O-N 3.44Å
447	L	94.6	Very high	93.1	Very high	4 Å²	4	42.2 Å²	42.2	2%	0.021	21%	0.214	C	C	.	.	H	α-helix	trans	-61.3	-35.1	179.3	-68.9	171.5	0	0	0	111.9	L434 S443 T451 L477 M480 N481 V484	L434-L447 HydrophobicContact CD2-CD1 4.11Å; L434-L447 HydrophobicContact CD2-CD2 4.1Å; L434-L447 HydrophobicContact CD2-CG 4Å; S443-L447 VanDerWaalsContact O-CB 3.28Å; S443-L447 WeakPolarHBondContact O-CB 3.46Å; S443-L447 WeakPolarHBondContact O-CG 3.5Å; S443-L447 PolarHBondContact O-N 3.44Å; L447-T451 WeakPolarHBondContact O-CB 3.26Å; L447-T451 PolarHBondContact O-N 2.93Å; L447-T451 PolarHBondContact O-OG1 3.4Å; L447-L477 HydrophobicContact CD2-CD2 3.86Å; L447-M480 HydrophobicContact CD1-CB 3.98Å; L447-M480 HydrophobicContact CD1-CE 4.48Å; L447-M480 HydrophobicContact CD2-CB 4.22Å; L447-M480 HydrophobicContact CD2-CE 3.65Å; L447-M480 HydrophobicContact CD2-SD 4.05Å; L447-N481 VanDerWaalsContact CB-OD1 3.24Å; L447-N481 WeakPolarHBondContact CB-OD1 3.29Å; L447-N481 PolarHBondContact O-ND2 3.29Å; L447-V484 HydrophobicContact CD1-CG2 3.9Å
448	Q	95.5	Very high	93.2	Very high	1 Å²	1	39.3 Å²	39.3	1%	0.005	20%	0.196	C	C	.	.	H	α-helix	trans	-73.6	-38.1	178.2	-160.7	75.5	60.3	0	0	112.3	L444 T445 V446 T451 A452 N481 C539 C542 A543	L444-Q448 WeakPolarHBondContact O-CB 3.44Å; L444-Q448 PolarHBondContact O-N 2.98Å; T445-Q448 PolarHBondContact O-N 3.07Å; V446-Q448 VanDerWaalsContact C-N 3.25Å; V446-Q448 PolarHBondContact O-N 3.45Å; Q448-T451 WeakPolarHBondContact O-CB 3.41Å; Q448-T451 PolarHBondContact O-N 3.48Å; Q448-A452 PolarHBondContact O-N 3.1Å; Q448-N481 PolarHBondContact N-OD1 3.25Å; Q448-C539 HydrophobicContact CG-CB 4.02Å; Q448-C539 WeakPolarHBondContact CG-O 3.39Å; Q448-C539 PolarHBondContact NE2-SG 3.41Å; Q448-C542 HydrophobicContact CG-CB 3.95Å; Q448-A543 HydrophobicContact CB-CB 4.14Å; Q448-A543 HydrophobicContact CG-CB 4.39Å
449	L	96.9	Very high	93.2	Very high	82 Å²	82	35.8 Å²	35.8	43%	0.429	18%	0.183	S	C	.	.	H	α-helix	trans	-65.5	-43.7	172.9	-70.7	173.6	0	0	0	112.2	T445 V446 T451 A452 L453 A543	T445-L449 HydrophobicContact CG2-CD1 4.4Å; T445-L449 WeakPolarHBondContact O-CG 3.48Å; T445-L449 PolarHBondContact O-N 3.16Å; T445-L449 VanDerWaalsContact O-N 3.1Å; V446-L449 PolarHBondContact O-N 3.07Å; L449-T451 VanDerWaalsContact C-N 3.28Å; L449-T451 PolarHBondContact O-N 3.14Å; L449-A452 WeakPolarHBondContact O-CB 3Å; L449-A452 PolarHBondContact O-N 3.01Å; L449-L453 PolarHBondContact O-N 2.94Å; L449-A543 HydrophobicContact CD1-CB 4.46Å; L449-A543 HydrophobicContact CD2-CB 3.57Å; L449-A543 HydrophobicContact CG-CB 3.6Å
450	L	96.7	Very high	93.2	Very high	75 Å²	75	41 Å²	41	39%	0.393	21%	0.209	S	C	.	.	H	α-helix	trans	-63.6	-35.7	175.4	-67.8	172.8	0	0	0	111.6	V446 L453 L454 L477	V446-L450 HydrophobicContact CG1-CD1 3.83Å; V446-L450 HydrophobicContact CG1-CG 4.31Å; V446-L450 WeakPolarHBondContact O-CG 3.45Å; V446-L450 PolarHBondContact O-N 3.44Å; L450-L453 PolarHBondContact O-N 3.5Å; L450-L454 WeakPolarHBondContact O-CG 3.49Å; L450-L454 PolarHBondContact O-N 3.21Å; L450-L477 HydrophobicContact CB-CD1 3.48Å; L450-L477 VanDerWaalsContact CB-CD1 3.48Å
451	T	96.9	Very high	92.9	Very high	0 Å²	0	42.2 Å²	42.2	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-63.3	-44	172.8	-61.1	0	0	0	0	111.5	L447 Q448 L449 L453 L454 F455 L474 L477 V478 N481	L447-T451 WeakPolarHBondContact O-CB 3.26Å; L447-T451 PolarHBondContact O-N 2.93Å; L447-T451 PolarHBondContact O-OG1 3.4Å; Q448-T451 WeakPolarHBondContact O-CB 3.41Å; Q448-T451 PolarHBondContact O-N 3.48Å; L449-T451 VanDerWaalsContact C-N 3.28Å; L449-T451 PolarHBondContact O-N 3.14Å; T451-L453 VanDerWaalsContact C-N 3.33Å; T451-L453 PolarHBondContact O-N 3.41Å; T451-L454 PolarHBondContact O-N 3.31Å; T451-F455 HydrophobicContact CG2-CD2 3.84Å; T451-F455 HydrophobicContact CG2-CE2 3.69Å; T451-F455 WeakPolarHBondContact O-CD2 3.41Å; T451-F455 PolarHBondContact O-N 3.49Å; T451-L474 HydrophobicContact CG2-CD1 4.18Å; T451-L477 WeakPolarHBondContact OG1-CB 3.06Å; T451-V478 HydrophobicContact CG2-CG2 3.57Å; T451-N481 PolarHBondContact OG1-ND2 2.94Å
452	A	97.4	Very high	92.6	Very high	7 Å²	7	40.6 Å²	40.6	6%	0.058	22%	0.22	C	C	.	.	H	α-helix	trans	-60.1	-43.4	175.4	0	0	0	0	0	112	Q448 L449 F455 M456 A536 C539 V540	Q448-A452 PolarHBondContact O-N 3.1Å; L449-A452 WeakPolarHBondContact O-CB 3Å; L449-A452 PolarHBondContact O-N 3.01Å; A452-F455 PolarHBondContact O-N 2.91Å; A452-M456 PolarHBondContact O-N 2.96Å; A452-A536 HydrophobicContact CB-CB 4.39Å; A452-A536 WeakPolarHBondContact CB-O 3.49Å; A452-C539 HydrophobicContact CB-CB 3.63Å; A452-V540 HydrophobicContact CB-CG2 3.74Å
453	L	96.8	Very high	92.4	Very high	102 Å²	102	38.8 Å²	38.8	53%	0.534	21%	0.213	S	C	.	.	H	α-helix	trans	-60.2	-47.7	176.4	-179.7	64	0	0	0	111.3	L449 L450 T451 M456 M457	L449-L453 PolarHBondContact O-N 2.94Å; L450-L453 PolarHBondContact O-N 3.5Å; T451-L453 VanDerWaalsContact C-N 3.33Å; T451-L453 PolarHBondContact O-N 3.41Å; L453-M456 PolarHBondContact O-N 3.09Å; L453-M457 WeakPolarHBondContact O-CB 3.49Å; L453-M457 PolarHBondContact O-N 3.03Å
454	L	96	Very high	91.9	Very high	13 Å²	13	40.6 Å²	40.6	7%	0.068	22%	0.222	C	C	.	.	H	α-helix	trans	-65.5	-38.3	179.5	-69.7	-171	0	0	0	113.1	L450 T451 M456 M457 V458 L470 L473 L474 L477	L450-L454 WeakPolarHBondContact O-CG 3.49Å; L450-L454 PolarHBondContact O-N 3.21Å; T451-L454 PolarHBondContact O-N 3.31Å; L454-M456 PolarHBondContact O-N 3.45Å; L454-M457 HydrophobicContact CD2-CE 3.61Å; L454-M457 PolarHBondContact O-N 2.91Å; L454-M457 VanDerWaalsContact O-N 3.15Å; L454-V458 WeakPolarHBondContact O-CG2 3.36Å; L454-V458 PolarHBondContact O-N 3Å; L454-L470 HydrophobicContact CD2-CD2 4.32Å; L454-L473 VanDerWaalsContact CD1-C 3.48Å; L454-L473 HydrophobicContact CD1-CB 3.55Å; L454-L474 HydrophobicContact CB-CB 4.33Å; L454-L474 HydrophobicContact CB-CD1 3.99Å; L454-L474 HydrophobicContact CD1-CB 4.29Å; L454-L477 HydrophobicContact CD1-CD1 3.56Å; L454-L477 HydrophobicContact CD1-CG 4.25Å; L454-L477 HydrophobicContact CG-CD1 4.16Å
455	F	95.1	Very high	91.7	Very high	1 Å²	1	48.2 Å²	48.2	0%	0.004	26%	0.256	C	S	.	.	H	α-helix	trans	-57.6	-37.7	172.5	-89	-62.6	0	0	0	112.5	A367 T451 A452 N459 L474 L532 F535 A536	A367-F455 HydrophobicContact CB-CE2 3.96Å; A367-F455 HydrophobicContact CB-CZ 4.33Å; T451-F455 HydrophobicContact CG2-CD2 3.84Å; T451-F455 HydrophobicContact CG2-CE2 3.69Å; T451-F455 WeakPolarHBondContact O-CD2 3.41Å; T451-F455 PolarHBondContact O-N 3.49Å; A452-F455 PolarHBondContact O-N 2.91Å; F455-N459 PolarHBondContact O-ND2 3.45Å; F455-L474 HydrophobicContact CD1-CD1 4.31Å; F455-L474 HydrophobicContact CD1-CD2 4.02Å; F455-L474 HydrophobicContact CD2-CD1 3.92Å; F455-L474 HydrophobicContact CE1-CD1 4.31Å; F455-L474 HydrophobicContact CE1-CD2 3.91Å; F455-L474 HydrophobicContact CE2-CD1 3.9Å; F455-L474 HydrophobicContact CG-CD1 4.12Å; F455-L474 HydrophobicContact CZ-CD1 4.1Å; F455-L474 HydrophobicContact CZ-CD2 4.37Å; F455-L532 HydrophobicContact CD1-CD2 4.21Å; F455-L532 WeakPolarHBondContact O-CD1 3.48Å; F455-F535 HydrophobicContact CD1-CB 3.89Å; F455-F535 HydrophobicContact CD1-CG 4.45Å; F455-F535 HydrophobicContact CD2-CB 3.88Å; F455-F535 HydrophobicContact CE1-CB 3.82Å; F455-F535 HydrophobicContact CE1-CD2 4.2Å; F455-F535 HydrophobicContact CE1-CG 4.02Å; F455-F535 HydrophobicContact CE2-CB 3.82Å; F455-F535 HydrophobicContact CG-CB 3.92Å; F455-F535 HydrophobicContact CZ-CB 3.79Å; F455-F535 HydrophobicContact CZ-CD1 4.45Å; F455-F535 HydrophobicContact CZ-CG 4.1Å; F455-A536 HydrophobicContact CB-CB 4.1Å
456	M	94.1	Very high	91.5	Very high	74 Å²	74	48.2 Å²	48.2	37%	0.365	26%	0.259	S	S	.	.	H	α-helix	trans	-76	-38.8	174	-62.8	-51.7	-59.4	0	0	112.1	A452 L453 L454 V458 N459 A536	A452-M456 PolarHBondContact O-N 2.96Å; L453-M456 PolarHBondContact O-N 3.09Å; L454-M456 PolarHBondContact O-N 3.45Å; M456-V458 PolarHBondContact O-N 3.41Å; M456-N459 WeakPolarHBondContact O-CB 3.24Å; M456-N459 PolarHBondContact O-N 3.38Å; M456-N459 PolarHBondContact O-ND2 3.41Å; M456-A536 HydrophobicContact CG-CB 3.76Å; M456-A536 HydrophobicContact SD-CB 3.66Å
457	M	92.3	Very high	91.2	Very high	68 Å²	68	45.5 Å²	45.5	34%	0.335	24%	0.241	S	C	.	.	H	α-helix	trans	-66.2	-24.6	-177.4	-156.4	154.1	89.1	0	0	113.3	L453 L454 N459 I460 L470	L453-M457 WeakPolarHBondContact O-CB 3.49Å; L453-M457 PolarHBondContact O-N 3.03Å; L454-M457 HydrophobicContact CD2-CE 3.61Å; L454-M457 PolarHBondContact O-N 2.91Å; L454-M457 VanDerWaalsContact O-N 3.15Å; M457-N459 PolarHBondContact O-N 2.95Å; M457-I460 HydrophobicContact CG-CD1 3.89Å; M457-I460 HydrophobicContact CG-CG1 4.49Å; M457-I460 WeakPolarHBondContact O-CB 3.41Å; M457-I460 PolarHBondContact O-N 2.81Å; M457-L470 HydrophobicContact CB-CD2 4.4Å; M457-L470 HydrophobicContact CE-CD2 3.37Å; M457-L470 HydrophobicContact CG-CD2 4.06Å
458	V	89.4	Confident	91.1	Very high	14 Å²	14	45.9 Å²	45.9	9%	0.085	24%	0.244	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.7	-21.5	170.1	165	0	0	0	0	113.3	L378 L454 M456 I460 F467 L470 L474 L532	L378-V458 HydrophobicContact CD1-CG1 3.93Å; L454-V458 WeakPolarHBondContact O-CG2 3.36Å; L454-V458 PolarHBondContact O-N 3Å; M456-V458 PolarHBondContact O-N 3.41Å; V458-I460 VanDerWaalsContact C-N 3.3Å; V458-F467 HydrophobicContact CG1-CE2 4.05Å; V458-L470 HydrophobicContact CG2-CB 4.22Å; V458-L474 HydrophobicContact CG2-CD2 4.42Å; V458-L532 HydrophobicContact CB-CD1 4.09Å; V458-L532 HydrophobicContact CG1-CD1 3.68Å
459	N	85.9	Confident	91.1	Very high	38 Å²	38	48.6 Å²	48.6	20%	0.203	26%	0.26	C	S	.	.	T	Hydrogen-bonded Turn	trans	-78.3	-11.1	174.4	-59.2	-89.6	0	0	0	113.5	F455 M456 M457 V528 I529	F455-N459 PolarHBondContact O-ND2 3.45Å; M456-N459 WeakPolarHBondContact O-CB 3.24Å; M456-N459 PolarHBondContact O-N 3.38Å; M456-N459 PolarHBondContact O-ND2 3.41Å; M457-N459 PolarHBondContact O-N 2.95Å; N459-V528 WeakPolarHBondContact OD1-CG1 3.48Å; N459-I529 HydrophobicContact CB-CG1 4.39Å; N459-I529 WeakPolarHBondContact OD1-CA 3.47Å; N459-I529 WeakPolarHBondContact OD1-CG1 3.29Å; N459-I529 PolarHBondContact OD1-N 3.32Å
460	I	86.6	Confident	91	Very high	109 Å²	109	45.5 Å²	45.5	56%	0.559	24%	0.244	S	C	*	.	S	Bend	trans	-78.4	132.4	-177	-58.2	-174.5	0	0	0	109.8	M457 V458 T462	M457-I460 HydrophobicContact CG-CD1 3.89Å; M457-I460 HydrophobicContact CG-CG1 4.49Å; M457-I460 WeakPolarHBondContact O-CB 3.41Å; M457-I460 PolarHBondContact O-N 2.81Å; V458-I460 VanDerWaalsContact C-N 3.3Å; I460-T462 PolarHBondContact O-N 2.98Å
461	C	81.4	Confident	90.9	Very high	59 Å²	59	42.2 Å²	42.2	40%	0.399	23%	0.227	S	C	.	.			trans	-60.7	129	177.6	-54.3	0	0	0	0	111.4	C385 I387	C385-C461 HydrophobicContact CB-CB 3.76Å; C385-C461 WeakPolarHBondContact CB-SG 3.48Å; C385-C461 CarbonylContact O-C 3.54Å; C385-C461 WeakPolarHBondContact O-CA 3.34Å; C385-C461 WeakPolarHBondContact SG-CB 3.29Å; C385-C461 CovalentContact SG-SG 2.03Å; C385-C461 PolarHBondContact SG-SG 3.45Å; I387-C461 HydrophobicContact CD1-CB 4.13Å; I387-C461 WeakPolarHBondContact CD1-O 3.36Å; I387-C461 HydrophobicContact CG1-CB 3.89Å
462	T	83.6	Confident	90.8	Very high	37 Å²	37	44.8 Å²	44.8	23%	0.227	24%	0.238	C	C	.	.	B	Isolated β-bridge	trans	-152.8	-173.6	-172.5	-167.9	0	0	0	0	111.9	C385 V386 I387 I460 F467 L470	C385-T462 PolarHBondContact O-N 3.3Å; V386-T462 CarbonylContact C-O 3.58Å; V386-T462 VanDerWaalsContact CA-O 3.27Å; V386-T462 WeakPolarHBondContact CA-O 3.45Å; I387-T462 PolarHBondContact N-O 3.36Å; I460-T462 PolarHBondContact O-N 2.98Å; T462-F467 HydrophobicContact CG2-CB 3.98Å; T462-L470 HydrophobicContact CG2-CD1 4.35Å
463	T	86.4	Confident	90.8	Very high	49 Å²	49	47.4 Å²	47.4	30%	0.301	25%	0.251	S	S	.	.			trans	-89.2	162.3	171.9	63.3	0	0	0	0	110.6	N388 F465 G466 F467	N388-T463 HydrophobicContact CB-CG2 4.46Å; T463-F465 PolarHBondContact O-N 2.96Å; T463-G466 CarbonylContact O-C 3.59Å; T463-G466 WeakPolarHBondContact O-CA 3.36Å; T463-G466 PolarHBondContact O-N 3.11Å; T463-G466 PolarHBondContact OG1-N 2.74Å; T463-G466 VanDerWaalsContact OG1-N 3.16Å; T463-F467 PolarHBondContact O-N 2.77Å
464	M	83.6	Confident	90.7	Very high	40 Å²	40	42.8 Å²	42.8	20%	0.197	23%	0.227	C	C	.	.	H	α-helix	trans	-55.9	-35.6	175.2	-70.5	-58.1	-73.9	0	0	112.8	L379 L384 V386 H393 T468	L379-M464 HydrophobicContact CD2-CE 4.32Å; L384-M464 HydrophobicContact CD1-CE 4.01Å; L384-M464 HydrophobicContact CD1-SD 3.83Å; V386-M464 HydrophobicContact CG1-CG 4.06Å; V386-M464 HydrophobicContact CG1-SD 4.23Å; V386-M464 HydrophobicContact CG2-SD 3.69Å; H393-M464 WeakPolarHBondContact NE2-CE 3.39Å; M464-T468 WeakPolarHBondContact O-CB 3.33Å; M464-T468 PolarHBondContact O-N 3.15Å; M464-T468 PolarHBondContact O-OG1 3.47Å
465	F	87.9	Confident	90.7	Very high	160 Å²	160	42.3 Å²	42.3	70%	0.702	22%	0.224	S	C	*	.	H	α-helix	trans	-63.1	-48.8	171.2	179.2	-100.1	0	0	0	111.9	T463 F467 T468 V469	T463-F465 PolarHBondContact O-N 2.96Å; F465-F467 PolarHBondContact O-N 2.96Å; F465-T468 PolarHBondContact O-N 3.16Å; F465-V469 HydrophobicContact CD1-CG2 4.34Å; F465-V469 HydrophobicContact CE1-CG2 3.92Å; F465-V469 HydrophobicContact CE2-CG2 4.29Å; F465-V469 HydrophobicContact CZ-CG2 3.89Å; F465-V469 WeakPolarHBondContact O-CG2 3.37Å; F465-V469 PolarHBondContact O-N 3.02Å
466	G	89.3	Confident	90.7	Very high	15 Å²	15	42.3 Å²	42.3	16%	0.155	22%	0.224	C	C	.	.	H	α-helix	trans	-58.6	-43.9	176.5	0	0	0	0	0	112.8	T463 V469 L470	T463-G466 CarbonylContact O-C 3.59Å; T463-G466 WeakPolarHBondContact O-CA 3.36Å; T463-G466 PolarHBondContact O-N 3.11Å; T463-G466 PolarHBondContact OG1-N 2.74Å; T463-G466 VanDerWaalsContact OG1-N 3.16Å; G466-V469 PolarHBondContact O-N 2.87Å; G466-L470 WeakPolarHBondContact O-CG 2.96Å; G466-L470 PolarHBondContact O-N 3.38Å
467	F	89.9	Confident	90.7	Very high	7 Å²	7	39.8 Å²	39.8	3%	0.031	21%	0.212	C	C	.	.	H	α-helix	trans	-61.6	-44.4	174.7	177.4	-105.6	0	0	0	112.2	L378 L379 L384 T416 V458 T462 T463 F465 V469 L470 L471	L378-F467 HydrophobicContact CB-CZ 4.26Å; L378-F467 HydrophobicContact CD1-CE2 4.23Å; L378-F467 HydrophobicContact CD1-CZ 4.2Å; L379-F467 HydrophobicContact CD2-CE1 4.11Å; L379-F467 HydrophobicContact CG-CE1 4.28Å; L384-F467 HydrophobicContact CD1-CD1 4.35Å; L384-F467 HydrophobicContact CD1-CE1 4.26Å; L384-F467 HydrophobicContact CD2-CD1 4.1Å; L384-F467 HydrophobicContact CD2-CD2 3.88Å; L384-F467 HydrophobicContact CD2-CE1 3.65Å; L384-F467 HydrophobicContact CD2-CE2 3.41Å; L384-F467 VanDerWaalsContact CD2-CE2 3.41Å; L384-F467 HydrophobicContact CD2-CG 4.2Å; L384-F467 HydrophobicContact CD2-CZ 3.29Å; T416-F467 HydrophobicContact CG2-CD1 4.32Å; T416-F467 HydrophobicContact CG2-CE1 4.29Å; V458-F467 HydrophobicContact CG1-CE2 4.05Å; T462-F467 HydrophobicContact CG2-CB 3.98Å; T463-F467 PolarHBondContact O-N 2.77Å; F465-F467 PolarHBondContact O-N 2.96Å; F467-V469 VanDerWaalsContact C-N 3.31Å; F467-V469 PolarHBondContact O-N 2.78Å; F467-L470 WeakPolarHBondContact O-CB 3.27Å; F467-L470 PolarHBondContact O-N 2.69Å; F467-L471 HydrophobicContact CD1-CD1 4.07Å; F467-L471 HydrophobicContact CD1-CG 4.45Å; F467-L471 HydrophobicContact CE1-CD1 3.36Å; F467-L471 HydrophobicContact CE1-CG 3.99Å; F467-L471 HydrophobicContact CE2-CD1 4.37Å; F467-L471 HydrophobicContact CE2-CD2 4.33Å; F467-L471 HydrophobicContact CE2-CG 4.2Å; F467-L471 HydrophobicContact CZ-CD1 3.54Å; F467-L471 HydrophobicContact CZ-CD2 4.1Å; F467-L471 HydrophobicContact CZ-CG 3.85Å; F467-L471 PolarHBondContact O-N 2.81Å
468	T	92.2	Very high	90.8	Very high	13 Å²	13	36.6 Å²	36.6	8%	0.08	20%	0.196	C	C	.	.	H	α-helix	trans	-60.5	-40.7	176	-56.5	0	0	0	0	111.7	T416 I419 M464 F465 L471 F472	T416-T468 HydrophobicContact CG2-CG2 4.23Å; T416-T468 WeakPolarHBondContact CG2-OG1 3.46Å; I419-T468 HydrophobicContact CB-CG2 3.84Å; I419-T468 HydrophobicContact CD1-CG2 4.36Å; I419-T468 HydrophobicContact CG2-CG2 3.57Å; M464-T468 WeakPolarHBondContact O-CB 3.33Å; M464-T468 PolarHBondContact O-N 3.15Å; M464-T468 PolarHBondContact O-OG1 3.47Å; F465-T468 PolarHBondContact O-N 3.16Å; T468-L471 PolarHBondContact O-N 3.41Å; T468-F472 WeakPolarHBondContact O-CB 3.43Å; T468-F472 PolarHBondContact O-N 3.49Å
469	V	94.4	Very high	91	Very high	57 Å²	57	36.5 Å²	36.5	35%	0.345	20%	0.196	S	C	.	.	H	α-helix	trans	-65.8	-41.5	174.8	171.5	0	0	0	0	111.6	F465 G466 F467 F472 L473	F465-V469 HydrophobicContact CD1-CG2 4.34Å; F465-V469 HydrophobicContact CE1-CG2 3.92Å; F465-V469 HydrophobicContact CE2-CG2 4.29Å; F465-V469 HydrophobicContact CZ-CG2 3.89Å; F465-V469 WeakPolarHBondContact O-CG2 3.37Å; F465-V469 PolarHBondContact O-N 3.02Å; G466-V469 PolarHBondContact O-N 2.87Å; F467-V469 VanDerWaalsContact C-N 3.31Å; F467-V469 PolarHBondContact O-N 2.78Å; V469-F472 PolarHBondContact O-N 2.71Å; V469-L473 HydrophobicContact CG1-CD1 4.02Å; V469-L473 HydrophobicContact CG1-CG 4.45Å; V469-L473 VanDerWaalsContact O-CG 3.31Å; V469-L473 WeakPolarHBondContact O-CG 3.2Å; V469-L473 PolarHBondContact O-N 3.45Å
470	L	94.6	Very high	91.2	Very high	18 Å²	18	34.9 Å²	34.9	9%	0.094	19%	0.188	C	C	.	.	H	α-helix	trans	-61	-44.8	174.8	-70.7	173.4	0	0	0	111.8	L454 M457 V458 T462 G466 F467 L473 L474	L454-L470 HydrophobicContact CD2-CD2 4.32Å; M457-L470 HydrophobicContact CB-CD2 4.4Å; M457-L470 HydrophobicContact CE-CD2 3.37Å; M457-L470 HydrophobicContact CG-CD2 4.06Å; V458-L470 HydrophobicContact CG2-CB 4.22Å; T462-L470 HydrophobicContact CG2-CD1 4.35Å; G466-L470 WeakPolarHBondContact O-CG 2.96Å; G466-L470 PolarHBondContact O-N 3.38Å; F467-L470 WeakPolarHBondContact O-CB 3.27Å; F467-L470 PolarHBondContact O-N 2.69Å; L470-L473 PolarHBondContact O-N 2.67Å; L470-L474 VanDerWaalsContact O-CB 3.29Å; L470-L474 WeakPolarHBondContact O-CB 3.47Å; L470-L474 PolarHBondContact O-N 2.6Å
471	L	94.4	Very high	91.5	Very high	5 Å²	5	29.7 Å²	29.7	3%	0.026	16%	0.161	C	C	.	.	H	α-helix	trans	-64.3	-42.6	175.6	-71.3	-174.5	0	0	0	112.4	T416 F467 T468 L473 L474 R475	T416-L471 HydrophobicContact CG2-CD1 4.04Å; F467-L471 HydrophobicContact CD1-CD1 4.07Å; F467-L471 HydrophobicContact CD1-CG 4.45Å; F467-L471 HydrophobicContact CE1-CD1 3.36Å; F467-L471 HydrophobicContact CE1-CG 3.99Å; F467-L471 HydrophobicContact CE2-CD1 4.37Å; F467-L471 HydrophobicContact CE2-CD2 4.33Å; F467-L471 HydrophobicContact CE2-CG 4.2Å; F467-L471 HydrophobicContact CZ-CD1 3.54Å; F467-L471 HydrophobicContact CZ-CD2 4.1Å; F467-L471 HydrophobicContact CZ-CG 3.85Å; F467-L471 PolarHBondContact O-N 2.81Å; T468-L471 PolarHBondContact O-N 3.41Å; L471-L473 PolarHBondContact O-N 3.21Å; L471-L474 PolarHBondContact O-N 3.19Å; L471-R475 WeakPolarHBondContact O-CG 2.92Å; L471-R475 PolarHBondContact O-N 3.09Å
472	F	96.3	Very high	91.9	Very high	54 Å²	54	28.3 Å²	28.3	24%	0.237	15%	0.148	C	C	.	.	H	α-helix	trans	-56.7	-49.8	175.4	176.8	-85.4	0	0	0	111.5	I419 L422 G423 A426 T468 V469 S476	I419-F472 WeakPolarHBondContact O-CD2 3.25Å; L422-F472 HydrophobicContact CB-CE2 4.03Å; G423-F472 VanDerWaalsContact N-CE2 3.31Å; A426-F472 HydrophobicContact CB-CE1 4.2Å; A426-F472 HydrophobicContact CB-CE2 4.2Å; A426-F472 HydrophobicContact CB-CZ 3.45Å; A426-F472 VanDerWaalsContact CB-CZ 3.45Å; T468-F472 WeakPolarHBondContact O-CB 3.43Å; T468-F472 PolarHBondContact O-N 3.49Å; V469-F472 PolarHBondContact O-N 2.71Å; F472-S476 WeakPolarHBondContact O-CB 3.33Å; F472-S476 PolarHBondContact O-N 2.88Å
473	L	96.2	Very high	92.1	Very high	62 Å²	62	27.8 Å²	27.8	33%	0.325	14%	0.144	S	C	.	.	H	α-helix	trans	-64.4	-41.6	178.2	-68	171.9	0	0	0	111.5	L454 V469 L470 L471 S476 L477	L454-L473 VanDerWaalsContact CD1-C 3.48Å; L454-L473 HydrophobicContact CD1-CB 3.55Å; V469-L473 HydrophobicContact CG1-CD1 4.02Å; V469-L473 HydrophobicContact CG1-CG 4.45Å; V469-L473 VanDerWaalsContact O-CG 3.31Å; V469-L473 WeakPolarHBondContact O-CG 3.2Å; V469-L473 PolarHBondContact O-N 3.45Å; L470-L473 PolarHBondContact O-N 2.67Å; L471-L473 PolarHBondContact O-N 3.21Å; L473-S476 WeakPolarHBondContact O-CB 3.33Å; L473-S476 PolarHBondContact O-N 3.14Å; L473-L477 WeakPolarHBondContact O-CG 3.29Å; L473-L477 PolarHBondContact O-N 3.34Å
474	L	96.4	Very high	92.3	Very high	5 Å²	5	25.5 Å²	25.5	3%	0.026	13%	0.13	C	C	.	.	H	α-helix	trans	-61.2	-52.4	177.8	178.5	61.6	0	0	0	111.5	T451 L454 F455 V458 L470 L471 S476 L477 V478	T451-L474 HydrophobicContact CG2-CD1 4.18Å; L454-L474 HydrophobicContact CB-CB 4.33Å; L454-L474 HydrophobicContact CB-CD1 3.99Å; L454-L474 HydrophobicContact CD1-CB 4.29Å; F455-L474 HydrophobicContact CD1-CD1 4.31Å; F455-L474 HydrophobicContact CD1-CD2 4.02Å; F455-L474 HydrophobicContact CD2-CD1 3.92Å; F455-L474 HydrophobicContact CE1-CD1 4.31Å; F455-L474 HydrophobicContact CE1-CD2 3.91Å; F455-L474 HydrophobicContact CE2-CD1 3.9Å; F455-L474 HydrophobicContact CG-CD1 4.12Å; F455-L474 HydrophobicContact CZ-CD1 4.1Å; F455-L474 HydrophobicContact CZ-CD2 4.37Å; V458-L474 HydrophobicContact CG2-CD2 4.42Å; L470-L474 VanDerWaalsContact O-CB 3.29Å; L470-L474 WeakPolarHBondContact O-CB 3.47Å; L470-L474 PolarHBondContact O-N 2.6Å; L471-L474 PolarHBondContact O-N 3.19Å; L474-S476 PolarHBondContact O-N 2.84Å; L474-L477 PolarHBondContact O-N 2.88Å; L474-V478 HydrophobicContact CD1-CG2 4.2Å; L474-V478 WeakPolarHBondContact O-CG2 3.35Å; L474-V478 PolarHBondContact O-N 3.36Å
475	R	94.9	Very high	92.7	Very high	4 Å²	4	23.6 Å²	23.6	2%	0.015	12%	0.121	C	C	.	.	H	α-helix	trans	-59.7	-36.8	177.1	-68.7	-169.5	77.9	113.4	1.3	111.8	V372 E424 L471 S479	V372-R475 VanDerWaalsContact CG2-NH2 3.35Å; E424-R475 HydrophobicContact CG-CB 4.42Å; E424-R475 IonicContact OE1-CZ 3.71Å; E424-R475 IonicContact OE1-NE 2.75Å; E424-R475 PolarHBondContact OE1-NE 3.39Å; E424-R475 IonicContact OE1-NH2 3.81Å; E424-R475 PolarHBondContact OE1-NH2 2.68Å; L471-R475 WeakPolarHBondContact O-CG 2.92Å; L471-R475 PolarHBondContact O-N 3.09Å; R475-S479 WeakPolarHBondContact O-CB 3.42Å; R475-S479 PolarHBondContact O-N 3.44Å
476	S	94.4	Very high	92.6	Very high	1 Å²	1	19.5 Å²	19.5	1%	0.007	10%	0.101	C	C	.	.	H	α-helix	trans	-63.2	-52.4	176	-154.9	0	0	0	0	112.6	G423 L427 F472 L473 L474 V478 S479 M480	G423-S476 WeakPolarHBondContact O-CA 3.24Å; G423-S476 WeakPolarHBondContact O-CB 3.37Å; G423-S476 PolarHBondContact O-OG 2.98Å; L427-S476 VanDerWaalsContact CB-OG 3.25Å; L427-S476 WeakPolarHBondContact CB-OG 3.34Å; L427-S476 WeakPolarHBondContact CD1-OG 3.17Å; L427-S476 WeakPolarHBondContact CG-OG 3.08Å; F472-S476 WeakPolarHBondContact O-CB 3.33Å; F472-S476 PolarHBondContact O-N 2.88Å; L473-S476 WeakPolarHBondContact O-CB 3.33Å; L473-S476 PolarHBondContact O-N 3.14Å; L474-S476 PolarHBondContact O-N 2.84Å; S476-V478 VanDerWaalsContact C-N 3.3Å; S476-V478 PolarHBondContact O-N 3.42Å; S476-S479 PolarHBondContact O-N 3.16Å; S476-M480 VanDerWaalsContact O-CG 3.26Å; S476-M480 WeakPolarHBondContact O-CG 3.37Å; S476-M480 PolarHBondContact O-N 3.27Å
477	L	95.1	Very high	92.4	Very high	20 Å²	20	21.1 Å²	21.1	11%	0.105	11%	0.106	C	C	.	.	H	α-helix	trans	-61.7	-37.9	179.4	-68.3	-175.1	0	0	0	112.5	L447 L450 T451 L454 L473 L474 M480 N481	L447-L477 HydrophobicContact CD2-CD2 3.86Å; L450-L477 HydrophobicContact CB-CD1 3.48Å; L450-L477 VanDerWaalsContact CB-CD1 3.48Å; T451-L477 WeakPolarHBondContact OG1-CB 3.06Å; L454-L477 HydrophobicContact CD1-CD1 3.56Å; L454-L477 HydrophobicContact CD1-CG 4.25Å; L454-L477 HydrophobicContact CG-CD1 4.16Å; L473-L477 WeakPolarHBondContact O-CG 3.29Å; L473-L477 PolarHBondContact O-N 3.34Å; L474-L477 PolarHBondContact O-N 2.88Å; L477-M480 HydrophobicContact CD2-SD 4.2Å; L477-M480 PolarHBondContact O-N 3.44Å; L477-N481 PolarHBondContact O-N 3.04Å; L477-N481 PolarHBondContact O-ND2 2.97Å
478	V	94.9	Very high	92.3	Very high	1 Å²	1	20.8 Å²	20.8	1%	0.006	10%	0.104	C	C	.	.	H	α-helix	trans	-71.6	-39.4	179	-173.6	0	0	0	0	111.8	A367 Y368 T451 L474 S476 M480 N481 F482	A367-V478 HydrophobicContact CB-CG1 3.99Å; A367-V478 HydrophobicContact CB-CG2 4.22Å; Y368-V478 VanDerWaalsContact CA-CG1 3.4Å; Y368-V478 HydrophobicContact CD2-CG1 4.11Å; Y368-V478 HydrophobicContact CG-CG1 4.4Å; T451-V478 HydrophobicContact CG2-CG2 3.57Å; L474-V478 HydrophobicContact CD1-CG2 4.2Å; L474-V478 WeakPolarHBondContact O-CG2 3.35Å; L474-V478 PolarHBondContact O-N 3.36Å; S476-V478 VanDerWaalsContact C-N 3.3Å; S476-V478 PolarHBondContact O-N 3.42Å; V478-M480 VanDerWaalsContact C-N 3.33Å; V478-M480 PolarHBondContact O-N 3.11Å; V478-N481 PolarHBondContact O-N 3.48Å; V478-F482 PolarHBondContact O-N 2.71Å
479	S	92.2	Very high	92.2	Very high	12 Å²	12	20.2 Å²	20.2	8%	0.084	10%	0.101	C	C	.	.	H	α-helix	trans	-58.3	-44.7	169.5	177	0	0	0	0	111.3	E424 R475 S476 F482 N483	E424-S479 WeakPolarHBondContact O-CB 3.35Å; E424-S479 PolarHBondContact O-OG 3.18Å; R475-S479 WeakPolarHBondContact O-CB 3.42Å; R475-S479 PolarHBondContact O-N 3.44Å; S476-S479 PolarHBondContact O-N 3.16Å; S479-F482 PolarHBondContact O-N 3.15Å; S479-N483 PolarHBondContact O-N 3.48Å; S479-N483 VanDerWaalsContact O-N 3.08Å; S479-N483 PolarHBondContact O-ND2 3.24Å
480	M	91.3	Very high	91.5	Very high	4 Å²	4	19.1 Å²	19.1	2%	0.02	10%	0.097	C	C	.	.	H	α-helix	trans	-59.5	-49	176.4	-68.6	171.5	78	0	0	111.6	L427 N431 L447 S476 L477 V478 F482 N483 V484	L427-M480 HydrophobicContact CB-CE 4.45Å; L427-M480 HydrophobicContact CB-CG 4.5Å; L427-M480 HydrophobicContact CB-SD 3.64Å; L427-M480 HydrophobicContact CD1-SD 4.3Å; N431-M480 HydrophobicContact CB-CB 4.48Å; N431-M480 HydrophobicContact CB-CE 3.6Å; N431-M480 HydrophobicContact CB-CG 4.03Å; N431-M480 WeakPolarHBondContact ND2-CA 3.26Å; N431-M480 PolarHBondContact ND2-O 3.39Å; L447-M480 HydrophobicContact CD1-CB 3.98Å; L447-M480 HydrophobicContact CD1-CE 4.48Å; L447-M480 HydrophobicContact CD2-CB 4.22Å; L447-M480 HydrophobicContact CD2-CE 3.65Å; L447-M480 HydrophobicContact CD2-SD 4.05Å; S476-M480 VanDerWaalsContact O-CG 3.26Å; S476-M480 WeakPolarHBondContact O-CG 3.37Å; S476-M480 PolarHBondContact O-N 3.27Å; L477-M480 HydrophobicContact CD2-SD 4.2Å; L477-M480 PolarHBondContact O-N 3.44Å; V478-M480 VanDerWaalsContact C-N 3.33Å; V478-M480 PolarHBondContact O-N 3.11Å; M480-F482 VanDerWaalsContact C-N 3.35Å; M480-F482 PolarHBondContact O-N 3.45Å; M480-N483 WeakPolarHBondContact O-CB 3.41Å; M480-N483 PolarHBondContact O-N 3.17Å; M480-N483 VanDerWaalsContact O-N 3.17Å; M480-V484 WeakPolarHBondContact O-CG2 3.41Å; M480-V484 PolarHBondContact O-N 2.98Å
481	N	92.7	Very high	91	Very high	1 Å²	1	20.4 Å²	20.4	1%	0.005	10%	0.103	C	C	.	.	H	α-helix	trans	-54.1	-49.2	176.7	-83.2	-64.4	0	0	0	111.6	L447 Q448 T451 L477 V478 N483 V484 V485	L447-N481 VanDerWaalsContact CB-OD1 3.24Å; L447-N481 WeakPolarHBondContact CB-OD1 3.29Å; L447-N481 PolarHBondContact O-ND2 3.29Å; Q448-N481 PolarHBondContact N-OD1 3.25Å; T451-N481 PolarHBondContact OG1-ND2 2.94Å; L477-N481 PolarHBondContact O-N 3.04Å; L477-N481 PolarHBondContact O-ND2 2.97Å; V478-N481 PolarHBondContact O-N 3.48Å; N481-N483 VanDerWaalsContact C-N 3.35Å; N481-N483 PolarHBondContact O-N 3.22Å; N481-V484 PolarHBondContact O-N 3.45Å; N481-V485 WeakPolarHBondContact O-CB 3.44Å; N481-V485 VanDerWaalsContact O-CG2 3.31Å; N481-V485 WeakPolarHBondContact O-CG2 3.48Å; N481-V485 PolarHBondContact O-N 3.13Å
482	F	90.3	Very high	90.7	Very high	29 Å²	29	20.4 Å²	20.4	13%	0.127	10%	0.103	C	C	.	.	H	α-helix	trans	-55.2	-49.9	177	-114.4	-54.6	0	0	0	111.8	W361 A364 Y368 V478 S479 M480 V484 V485 Y486	W361-F482 HydrophobicContact CE3-CE1 4.29Å; W361-F482 HydrophobicContact CZ3-CE1 4.42Å; A364-F482 HydrophobicContact CB-CD1 4.12Å; A364-F482 HydrophobicContact CB-CD2 4.32Å; A364-F482 HydrophobicContact CB-CE1 4.16Å; A364-F482 HydrophobicContact CB-CE2 4.38Å; A364-F482 HydrophobicContact CB-CG 4.2Å; A364-F482 HydrophobicContact CB-CZ 4.3Å; A364-F482 WeakPolarHBondContact O-CE2 3.33Å; Y368-F482 HydrophobicContact CD1-CE2 4.31Å; Y368-F482 HydrophobicContact CD2-CD2 4.5Å; Y368-F482 HydrophobicContact CG-CD2 4.14Å; Y368-F482 AromaticContact CG-CE2 3.96Å; Y368-F482 HydrophobicContact CG-CE2 3.96Å; V478-F482 PolarHBondContact O-N 2.71Å; S479-F482 PolarHBondContact O-N 3.15Å; M480-F482 VanDerWaalsContact C-N 3.35Å; M480-F482 PolarHBondContact O-N 3.45Å; F482-V484 PolarHBondContact O-N 3.43Å; F482-V485 PolarHBondContact O-N 2.89Å; F482-Y486 HydrophobicContact CD1-CD2 4.04Å; F482-Y486 AromaticContact CD1-CE2 3.76Å; F482-Y486 HydrophobicContact CD1-CE2 3.76Å; F482-Y486 HydrophobicContact CE1-CE2 4.12Å; F482-Y486 WeakPolarHBondContact O-CD2 3.49Å; F482-Y486 PolarHBondContact O-N 3.3Å
483	N	87.8	Confident	90.1	Very high	27 Å²	27	17.8 Å²	17.8	14%	0.144	9%	0.092	C	C	.	.	H	α-helix	trans	-57.3	-44.5	178.6	-78.1	-69.5	0	0	0	112.5	T251 S479 M480 N481 I487	T251-N483 VanDerWaalsContact CG2-OD1 3.23Å; T251-N483 WeakPolarHBondContact CG2-OD1 3.38Å; S479-N483 PolarHBondContact O-N 3.48Å; S479-N483 VanDerWaalsContact O-N 3.08Å; S479-N483 PolarHBondContact O-ND2 3.24Å; M480-N483 WeakPolarHBondContact O-CB 3.41Å; M480-N483 PolarHBondContact O-N 3.17Å; M480-N483 VanDerWaalsContact O-N 3.17Å; N481-N483 VanDerWaalsContact C-N 3.35Å; N481-N483 PolarHBondContact O-N 3.22Å; N483-I487 WeakPolarHBondContact O-CG1 3.43Å; N483-I487 PolarHBondContact O-N 3.28Å
484	V	89.4	Confident	89.3	Confident	0 Å²	0	15.9 Å²	15.9	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-67.6	-42.2	178.4	-172.3	0	0	0	0	111.7	N431 L435 R440 L444 L447 M480 N481 F482 Y486 I487 Y488	N431-V484 WeakPolarHBondContact OD1-CG2 3.32Å; L435-V484 HydrophobicContact CD1-CG2 4.18Å; L435-V484 HydrophobicContact CD2-CB 4.19Å; L435-V484 HydrophobicContact CD2-CG1 3.46Å; L435-V484 VanDerWaalsContact CD2-CG1 3.46Å; L435-V484 HydrophobicContact CD2-CG2 3.72Å; L435-V484 HydrophobicContact CG-CG2 4.22Å; R440-V484 HydrophobicContact CB-CG1 4.47Å; L444-V484 HydrophobicContact CD1-CG1 4.2Å; L444-V484 HydrophobicContact CD2-CB 3.68Å; L444-V484 HydrophobicContact CD2-CG1 3.63Å; L444-V484 HydrophobicContact CG-CB 4.15Å; L444-V484 HydrophobicContact CG-CG1 3.53Å; L447-V484 HydrophobicContact CD1-CG2 3.9Å; M480-V484 WeakPolarHBondContact O-CG2 3.41Å; M480-V484 PolarHBondContact O-N 2.98Å; N481-V484 PolarHBondContact O-N 3.45Å; F482-V484 PolarHBondContact O-N 3.43Å; V484-Y486 VanDerWaalsContact C-N 3.33Å; V484-Y486 PolarHBondContact O-N 3.11Å; V484-I487 PolarHBondContact O-N 3.36Å; V484-Y488 WeakPolarHBondContact O-CB 3.28Å; V484-Y488 PolarHBondContact O-N 2.89Å
485	V	91.6	Very high	88.1	Confident	0 Å²	0	19.1 Å²	19.1	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-60.1	-42.1	178.9	167.9	0	0	0	0	111.1	W361 L444 N481 F482 T489	W361-V485 HydrophobicContact CD2-CG1 3.69Å; W361-V485 HydrophobicContact CG-CG1 3.61Å; W361-V485 HydrophobicContact CZ2-CG1 4.33Å; L444-V485 HydrophobicContact CD2-CB 4.4Å; L444-V485 HydrophobicContact CD2-CG2 3.41Å; L444-V485 VanDerWaalsContact CD2-CG2 3.41Å; N481-V485 WeakPolarHBondContact O-CB 3.44Å; N481-V485 VanDerWaalsContact O-CG2 3.31Å; N481-V485 WeakPolarHBondContact O-CG2 3.48Å; N481-V485 PolarHBondContact O-N 3.13Å; F482-V485 PolarHBondContact O-N 2.89Å; V485-T489 VanDerWaalsContact O-CB 3.29Å; V485-T489 WeakPolarHBondContact O-CB 3.36Å; V485-T489 PolarHBondContact O-N 3.23Å; V485-T489 PolarHBondContact O-OG1 3.01Å
486	Y	87.1	Confident	87	Confident	75 Å²	75	22.1 Å²	22.1	29%	0.294	12%	0.119	S	C	.	.	H	α-helix	trans	-58.9	-50.8	172.9	-93.7	-85.6	0	0	0	112	W361 F482 V484 T489 A490 M502	W361-Y486 AromaticContact CH2-CD1 3.55Å; W361-Y486 HydrophobicContact CH2-CD1 3.55Å; W361-Y486 AromaticContact CH2-CD2 3.92Å; W361-Y486 HydrophobicContact CH2-CD2 3.92Å; W361-Y486 AromaticContact CH2-CE1 3.37Å; W361-Y486 HydrophobicContact CH2-CE1 3.37Å; W361-Y486 AromaticContact CH2-CE2 3.75Å; W361-Y486 HydrophobicContact CH2-CE2 3.75Å; W361-Y486 AromaticContact CH2-CG 3.82Å; W361-Y486 HydrophobicContact CH2-CG 3.82Å; W361-Y486 AromaticContact CH2-CZ 3.45Å; W361-Y486 VanDerWaalsContact CH2-CZ 3.45Å; W361-Y486 HydrophobicContact CZ2-CD1 4.15Å; W361-Y486 HydrophobicContact CZ2-CE1 4.38Å; W361-Y486 HydrophobicContact CZ2-CG 4.24Å; W361-Y486 HydrophobicContact CZ3-CD1 4.45Å; W361-Y486 HydrophobicContact CZ3-CD2 4.2Å; W361-Y486 AromaticContact CZ3-CE1 3.99Å; W361-Y486 HydrophobicContact CZ3-CE1 3.99Å; W361-Y486 AromaticContact CZ3-CE2 3.69Å; W361-Y486 HydrophobicContact CZ3-CE2 3.69Å; W361-Y486 AromaticContact CZ3-CZ 3.55Å; F482-Y486 HydrophobicContact CD1-CD2 4.04Å; F482-Y486 AromaticContact CD1-CE2 3.76Å; F482-Y486 HydrophobicContact CD1-CE2 3.76Å; F482-Y486 HydrophobicContact CE1-CE2 4.12Å; F482-Y486 WeakPolarHBondContact O-CD2 3.49Å; F482-Y486 PolarHBondContact O-N 3.3Å; V484-Y486 VanDerWaalsContact C-N 3.33Å; V484-Y486 PolarHBondContact O-N 3.11Å; Y486-T489 PolarHBondContact O-N 3.38Å; Y486-A490 PolarHBondContact O-N 3.42Å; Y486-A490 VanDerWaalsContact O-N 3.15Å; Y486-M502 HydrophobicContact CE1-SD 4.48Å
487	I	84.1	Confident	86	Confident	49 Å²	49	22.2 Å²	22.2	25%	0.251	12%	0.119	S	C	.	.	H	α-helix	trans	-61.4	-52.2	-178.5	-68.3	165.7	0	0	0	110.8	L435 N483 V484 T489 A490 E491	L435-I487 HydrophobicContact CD1-CD1 3.98Å; N483-I487 WeakPolarHBondContact O-CG1 3.43Å; N483-I487 PolarHBondContact O-N 3.28Å; V484-I487 PolarHBondContact O-N 3.36Å; I487-T489 VanDerWaalsContact C-N 3.3Å; I487-T489 PolarHBondContact O-N 3.2Å; I487-A490 WeakPolarHBondContact O-CB 3.4Å; I487-A490 PolarHBondContact O-N 3.32Å; I487-A490 VanDerWaalsContact O-N 3.09Å; I487-E491 HydrophobicContact CG2-CG 4.33Å; I487-E491 WeakPolarHBondContact O-CG 3.41Å; I487-E491 PolarHBondContact O-N 2.99Å
488	Y	88.9	Confident	85.2	Confident	0 Å²	0	23.4 Å²	23.4	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-61.8	-37.9	-178.1	-179.8	-95.1	0	0	0	112.1	L357 R440 L444 V484 A490 E491 V492 L549 I551 T553	L357-Y488 HydrophobicContact CD1-CD1 4.47Å; L357-Y488 HydrophobicContact CD1-CE1 4.24Å; L357-Y488 HydrophobicContact CD2-CD1 3.59Å; L357-Y488 HydrophobicContact CD2-CE1 3.73Å; L357-Y488 HydrophobicContact CG-CE1 4.31Å; R440-Y488 HydrophobicContact CB-CD2 3.57Å; R440-Y488 HydrophobicContact CB-CE2 4.39Å; R440-Y488 HydrophobicContact CB-CG 4.36Å; R440-Y488 HydrophobicContact CG-CD2 4.26Å; L444-Y488 HydrophobicContact CD1-CD1 4.32Å; L444-Y488 HydrophobicContact CD1-CG 4.16Å; V484-Y488 WeakPolarHBondContact O-CB 3.28Å; V484-Y488 PolarHBondContact O-N 2.89Å; Y488-A490 VanDerWaalsContact C-N 3.33Å; Y488-A490 PolarHBondContact O-N 3.46Å; Y488-E491 PolarHBondContact O-N 2.64Å; Y488-V492 HydrophobicContact CD1-CG2 3.9Å; Y488-V492 HydrophobicContact CD2-CG2 4.11Å; Y488-V492 HydrophobicContact CE1-CB 4.48Å; Y488-V492 HydrophobicContact CE1-CG2 3.42Å; Y488-V492 VanDerWaalsContact CE1-CG2 3.42Å; Y488-V492 HydrophobicContact CE2-CG2 3.68Å; Y488-V492 HydrophobicContact CG-CG2 4.22Å; Y488-V492 WeakPolarHBondContact O-CB 3.34Å; Y488-V492 WeakPolarHBondContact O-CG2 3.48Å; Y488-V492 PolarHBondContact O-N 3.28Å; Y488-L549 HydrophobicContact CE1-CD1 3.72Å; Y488-L549 HydrophobicContact CE1-CD2 4.21Å; Y488-I551 PolarHBondContact OH-O 3.44Å; Y488-T553 HydrophobicContact CD2-CG2 3.86Å; Y488-T553 HydrophobicContact CE2-CG2 3.8Å
489	T	88.6	Confident	84.2	Confident	1 Å²	1	27.4 Å²	27.4	1%	0.006	15%	0.151	C	C	.	.	H	α-helix	trans	-64.3	-37.1	175.5	-56.7	0	0	0	0	112.1	W361 V485 Y486 I487 Y493 M502 C505	W361-T489 HydrophobicContact CZ2-CG2 4.25Å; W361-T489 PolarHBondContact NE1-OG1 3.01Å; V485-T489 VanDerWaalsContact O-CB 3.29Å; V485-T489 WeakPolarHBondContact O-CB 3.36Å; V485-T489 PolarHBondContact O-N 3.23Å; V485-T489 PolarHBondContact O-OG1 3.01Å; Y486-T489 PolarHBondContact O-N 3.38Å; I487-T489 VanDerWaalsContact C-N 3.3Å; I487-T489 PolarHBondContact O-N 3.2Å; T489-Y493 HydrophobicContact CG2-CD2 4.14Å; T489-Y493 HydrophobicContact CG2-CE2 4.06Å; T489-Y493 WeakPolarHBondContact O-CD2 3.35Å; T489-M502 HydrophobicContact CG2-CB 4.43Å; T489-M502 HydrophobicContact CG2-CG 4.28Å; T489-C505 HydrophobicContact CG2-CB 4.38Å
490	A	80.9	Confident	83.6	Confident	33 Å²	33	29.7 Å²	29.7	27%	0.273	16%	0.161	S	C	.	.	H	α-helix	trans	-71.2	-36.3	175.2	0	0	0	0	0	112.5	Y486 I487 Y488 R498	Y486-A490 PolarHBondContact O-N 3.42Å; Y486-A490 VanDerWaalsContact O-N 3.15Å; I487-A490 WeakPolarHBondContact O-CB 3.4Å; I487-A490 PolarHBondContact O-N 3.32Å; I487-A490 VanDerWaalsContact O-N 3.09Å; Y488-A490 VanDerWaalsContact C-N 3.33Å; Y488-A490 PolarHBondContact O-N 3.46Å; A490-R498 WeakPolarHBondContact O-CD 3.41Å; A490-R498 PolarHBondContact O-NE 2.98Å
491	E	83.9	Confident	83.3	Confident	46 Å²	46	29.5 Å²	29.5	22%	0.215	16%	0.16	C	C	.	.	H	α-helix	trans	-75.9	-36.5	-180	-69.6	175.6	166.5	0	0	113.4	R440 I487 Y488 T553	R440-E491 IonicContact CZ-OE1 3.27Å; R440-E491 IonicContact CZ-OE2 2.7Å; R440-E491 IonicContact NE-OE1 2.74Å; R440-E491 PolarHBondContact NE-OE1 2.7Å; R440-E491 IonicContact NE-OE2 3.19Å; R440-E491 PolarHBondContact NE-OE2 2.99Å; R440-E491 IonicContact NH2-OE1 3.63Å; R440-E491 PolarHBondContact NH2-OE1 3.38Å; R440-E491 IonicContact NH2-OE2 2.76Å; I487-E491 HydrophobicContact CG2-CG 4.33Å; I487-E491 WeakPolarHBondContact O-CG 3.41Å; I487-E491 PolarHBondContact O-N 2.99Å; Y488-E491 PolarHBondContact O-N 2.64Å; E491-T553 HydrophobicContact CB-CG2 3.69Å; E491-T553 WeakPolarHBondContact OE2-CB 3.42Å; E491-T553 PolarHBondContact OE2-OG1 3.42Å
492	V	87.8	Confident	82.9	Confident	4 Å²	4	31.5 Å²	31.5	2%	0.024	17%	0.17	C	C	.	.	H	α-helix	trans	-70.1	-43.6	-175.8	156.2	0	0	0	0	114.1	T353 L357 Y488 I551 T553	T353-V492 HydrophobicContact CG2-CG1 3.66Å; L357-V492 HydrophobicContact CD1-CG1 4.37Å; Y488-V492 HydrophobicContact CD1-CG2 3.9Å; Y488-V492 HydrophobicContact CD2-CG2 4.11Å; Y488-V492 HydrophobicContact CE1-CB 4.48Å; Y488-V492 HydrophobicContact CE1-CG2 3.42Å; Y488-V492 VanDerWaalsContact CE1-CG2 3.42Å; Y488-V492 HydrophobicContact CE2-CG2 3.68Å; Y488-V492 HydrophobicContact CG-CG2 4.22Å; Y488-V492 WeakPolarHBondContact O-CB 3.34Å; Y488-V492 WeakPolarHBondContact O-CG2 3.48Å; Y488-V492 PolarHBondContact O-N 3.28Å; V492-I551 HydrophobicContact CG2-CG2 4.48Å; V492-T553 HydrophobicContact CG2-CG2 3.65Å
493	Y	83.8	Confident	82.6	Confident	0 Å²	0	31.6 Å²	31.6	0%	0	18%	0.18	C	C	.	.	S	Bend	trans	-84.1	137.7	-172.6	-72.4	-66.1	0	0	0	111.5	L345 F350 S354 L357 T489 R498	L345-Y493 HydrophobicContact CD2-CD1 4.13Å; L345-Y493 HydrophobicContact CD2-CE1 3.55Å; F350-Y493 HydrophobicContact CD1-CD1 4.3Å; F350-Y493 HydrophobicContact CD1-CE1 4.33Å; S354-Y493 WeakPolarHBondContact CA-OH 3.24Å; S354-Y493 PolarHBondContact OG-OH 3Å; L357-Y493 HydrophobicContact CD1-CE2 4.01Å; T489-Y493 HydrophobicContact CG2-CD2 4.14Å; T489-Y493 HydrophobicContact CG2-CE2 4.06Å; T489-Y493 WeakPolarHBondContact O-CD2 3.35Å; Y493-R498 PolarHBondContact O-NE 3.18Å; Y493-R498 PolarHBondContact O-NH2 3.18Å
494	P	78.8	Confident	82.6	Confident	21 Å²	21	33.6 Å²	33.6	14%	0.136	19%	0.187	C	C	.	.			trans	-66.5	157.8	173.3	30.3	-35.8	0	0	0	110.4	F350 I496 A497 R498 L559	F350-P494 HydrophobicContact CE2-CG 4.4Å; F350-P494 HydrophobicContact CZ-CG 4Å; P494-I496 VanDerWaalsContact C-N 3.25Å; P494-I496 PolarHBondContact O-N 2.94Å; P494-I496 VanDerWaalsContact O-N 3.08Å; P494-A497 HydrophobicContact CG-CB 4.13Å; P494-A497 CarbonylContact O-C 3.6Å; P494-A497 PolarHBondContact O-N 3.24Å; P494-R498 WeakPolarHBondContact O-CB 3.15Å; P494-R498 PolarHBondContact O-N 2.85Å; P494-L559 HydrophobicContact CB-CB 4.3Å
495	T	71.4	Confident	82.6	Confident	74 Å²	74	33.6 Å²	33.6	45%	0.454	19%	0.187	S	C	.	.	H	α-helix	trans	-56.3	-34.8	-167.5	-57.8	0	0	0	0	114.1	R498 L559	T495-R498 PolarHBondContact OG1-NH1 3.36Å; T495-R498 PolarHBondContact OG1-NH2 2.86Å; T495-L559 PolarHBondContact OG1-O 2.98Å
496	I	71.3	Confident	82.4	Confident	67 Å²	67	35.1 Å²	35.1	34%	0.344	20%	0.197	S	C	.	.	H	α-helix	trans	-64.8	-39.5	175.7	-62.5	166.8	0	0	0	112.3	G340 P494 N561	G340-I496 VanDerWaalsContact N-CG2 3.35Å; P494-I496 VanDerWaalsContact C-N 3.25Å; P494-I496 PolarHBondContact O-N 2.94Å; P494-I496 VanDerWaalsContact O-N 3.08Å; I496-N561 WeakPolarHBondContact CD1-ND2 3.3Å; I496-N561 WeakPolarHBondContact CG1-ND2 3.27Å
497	A	74.9	Confident	82.5	Confident	2 Å²	2	33.8 Å²	33.8	2%	0.017	20%	0.198	C	C	.	.	H	α-helix	trans	-96.6	-15.2	-174.6	0	0	0	0	0	113.6	I344 P494 S499 L500 G501	I344-A497 HydrophobicContact CG2-CB 4.14Å; P494-A497 HydrophobicContact CG-CB 4.13Å; P494-A497 CarbonylContact O-C 3.6Å; P494-A497 PolarHBondContact O-N 3.24Å; A497-S499 PolarHBondContact O-N 2.98Å; A497-L500 PolarHBondContact O-N 2.91Å; A497-L500 VanDerWaalsContact O-N 3.15Å; A497-G501 PolarHBondContact O-N 3.36Å
498	R	78.1	Confident	82.9	Confident	46 Å²	46	34.8 Å²	34.8	17%	0.174	20%	0.201	C	C	.	.	H	α-helix	trans	-55.5	-45.5	-172.7	-173.8	179.5	-66.3	120.4	11.6	113.9	A490 Y493 P494 T495 M502	A490-R498 WeakPolarHBondContact O-CD 3.41Å; A490-R498 PolarHBondContact O-NE 2.98Å; Y493-R498 PolarHBondContact O-NE 3.18Å; Y493-R498 PolarHBondContact O-NH2 3.18Å; P494-R498 WeakPolarHBondContact O-CB 3.15Å; P494-R498 PolarHBondContact O-N 2.85Å; T495-R498 PolarHBondContact OG1-NH1 3.36Å; T495-R498 PolarHBondContact OG1-NH2 2.86Å; R498-M502 WeakPolarHBondContact O-CB 3.43Å; R498-M502 PolarHBondContact O-N 3.47Å
499	S	72.4	Confident	83	Confident	85 Å²	85	34.9 Å²	34.9	59%	0.594	20%	0.202	S	C	*	.	H	α-helix	trans	-65.6	-41.2	179.1	-177.2	0	0	0	0	112	A497 G503	A497-S499 PolarHBondContact O-N 2.98Å; S499-G503 PolarHBondContact O-N 3.35Å
500	L	80.4	Confident	83.1	Confident	59 Å²	59	36.1 Å²	36.1	31%	0.309	21%	0.206	S	C	.	.	H	α-helix	trans	-67.7	-46.6	176.2	-70	167.8	0	0	0	111.9	G340 L345 A497 M502 G503 F504	G340-L500 WeakPolarHBondContact O-CD1 3.35Å; L345-L500 HydrophobicContact CD1-CB 4.38Å; A497-L500 PolarHBondContact O-N 2.91Å; A497-L500 VanDerWaalsContact O-N 3.15Å; L500-M502 VanDerWaalsContact C-N 3.33Å; L500-M502 PolarHBondContact O-N 3.41Å; L500-G503 PolarHBondContact O-N 3.47Å; L500-G503 VanDerWaalsContact O-N 3.09Å; L500-F504 WeakPolarHBondContact O-CD2 3.28Å; L500-F504 PolarHBondContact O-N 3.11Å
501	G	84.7	Confident	83.8	Confident	0 Å²	0	37.5 Å²	37.5	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-55.4	-48.2	176.7	0	0	0	0	0	111.6	A497 G503 C505	A497-G501 PolarHBondContact O-N 3.36Å; G501-G503 PolarHBondContact O-N 2.03Å; G501-C505 VanDerWaalsContact O-CB 3.28Å; G501-C505 WeakPolarHBondContact O-CB 3.06Å; G501-C505 PolarHBondContact O-N 2.96Å; G501-C505 PolarHBondContact O-SG 2.96Å
502	M	85	Confident	84.3	Confident	44 Å²	44	35.3 Å²	35.3	22%	0.217	20%	0.198	C	C	.	.	H	α-helix	trans	-65.3	-36.7	175.9	-148	-151.7	-52.7	0	0	112.4	F231 W361 Y486 T489 R498 L500 C505 T506	F231-M502 HydrophobicContact CE1-CE 4.44Å; F231-M502 HydrophobicContact CE1-SD 4.35Å; W361-M502 HydrophobicContact CH2-CG 4.38Å; W361-M502 HydrophobicContact CZ2-CG 4.22Å; Y486-M502 HydrophobicContact CE1-SD 4.48Å; T489-M502 HydrophobicContact CG2-CB 4.43Å; T489-M502 HydrophobicContact CG2-CG 4.28Å; R498-M502 WeakPolarHBondContact O-CB 3.43Å; R498-M502 PolarHBondContact O-N 3.47Å; L500-M502 VanDerWaalsContact C-N 3.33Å; L500-M502 PolarHBondContact O-N 3.41Å; M502-C505 PolarHBondContact O-N 3.19Å; M502-T506 WeakPolarHBondContact O-CB 3.44Å; M502-T506 VanDerWaalsContact O-CG2 3.29Å; M502-T506 WeakPolarHBondContact O-CG2 3.46Å; M502-T506 PolarHBondContact O-N 2.9Å; M502-T506 PolarHBondContact O-OG1 3.28Å
503	G	82.7	Confident	84.6	Confident	31 Å²	31	35.1 Å²	35.1	32%	0.32	20%	0.197	S	C	.	.	H	α-helix	trans	-65.2	-42.8	177	0	0	0	0	0	114	S499 L500 G501 T506 S507	S499-G503 PolarHBondContact O-N 3.35Å; L500-G503 PolarHBondContact O-N 3.47Å; L500-G503 VanDerWaalsContact O-N 3.09Å; G501-G503 PolarHBondContact O-N 2.03Å; G503-T506 WeakPolarHBondContact CA-OG1 3.47Å; G503-T506 PolarHBondContact O-OG1 2.82Å; G503-S507 PolarHBondContact O-N 3Å; G503-S507 VanDerWaalsContact O-N 3.13Å; G503-S507 PolarHBondContact O-OG 3.44Å
504	F	87.6	Confident	85.1	Confident	68 Å²	68	36.2 Å²	36.2	30%	0.298	20%	0.202	S	C	.	.	H	α-helix	trans	-66.3	-47.8	172.9	-86.4	-92.7	0	0	0	111.2	W342 L345 W358 L500 T506 S507 F508	W342-F504 HydrophobicContact CB-CE2 4.12Å; W342-F504 HydrophobicContact CB-CZ 4.31Å; L345-F504 HydrophobicContact CD1-CB 4.23Å; L345-F504 HydrophobicContact CD1-CD2 3.42Å; L345-F504 VanDerWaalsContact CD1-CD2 3.42Å; L345-F504 HydrophobicContact CD1-CE2 3.92Å; L345-F504 HydrophobicContact CD1-CG 3.89Å; W358-F504 HydrophobicContact CZ2-CB 4.32Å; W358-F504 HydrophobicContact CZ2-CD1 4.18Å; W358-F504 HydrophobicContact CZ2-CG 4.4Å; L500-F504 WeakPolarHBondContact O-CD2 3.28Å; L500-F504 PolarHBondContact O-N 3.11Å; F504-T506 PolarHBondContact O-N 3.35Å; F504-S507 WeakPolarHBondContact O-CB 3.26Å; F504-S507 PolarHBondContact O-N 3.29Å; F504-F508 WeakPolarHBondContact O-CD2 3.45Å; F504-F508 PolarHBondContact O-N 3.29Å
505	C	91	Very high	85.9	Confident	0 Å²	0	38.7 Å²	38.7	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-56.8	-46.6	177.6	-75.4	0	0	0	0	113.2	W361 T489 G501 M502 S507 F508 S509	W361-C505 HydrophobicContact CB-CB 4.37Å; W361-C505 WeakPolarHBondContact CB-O 3.5Å; W361-C505 VanDerWaalsContact CD1-CB 3.46Å; W361-C505 HydrophobicContact CD2-CB 3.74Å; W361-C505 HydrophobicContact CG-CB 3.63Å; W361-C505 HydrophobicContact CZ2-CB 4.15Å; T489-C505 HydrophobicContact CG2-CB 4.38Å; G501-C505 VanDerWaalsContact O-CB 3.28Å; G501-C505 WeakPolarHBondContact O-CB 3.06Å; G501-C505 PolarHBondContact O-N 2.96Å; G501-C505 PolarHBondContact O-SG 2.96Å; M502-C505 PolarHBondContact O-N 3.19Å; C505-S507 VanDerWaalsContact C-N 3.26Å; C505-S507 PolarHBondContact O-N 2.92Å; C505-F508 PolarHBondContact O-N 3.18Å; C505-S509 PolarHBondContact O-N 2.83Å
506	T	87.4	Confident	87.1	Confident	33 Å²	33	35.1 Å²	35.1	20%	0.202	19%	0.192	C	C	.	.	H	α-helix	trans	-65.6	-27.6	176.1	48.4	0	0	0	0	112.7	W361 M502 G503 F504 S509 R510	W361-T506 HydrophobicContact CE3-CG2 4.25Å; W361-T506 HydrophobicContact CH2-CG2 3.48Å; W361-T506 VanDerWaalsContact CH2-CG2 3.48Å; W361-T506 HydrophobicContact CZ2-CG2 4.42Å; W361-T506 HydrophobicContact CZ3-CG2 3.41Å; W361-T506 VanDerWaalsContact CZ3-CG2 3.41Å; M502-T506 WeakPolarHBondContact O-CB 3.44Å; M502-T506 VanDerWaalsContact O-CG2 3.29Å; M502-T506 WeakPolarHBondContact O-CG2 3.46Å; M502-T506 PolarHBondContact O-N 2.9Å; M502-T506 PolarHBondContact O-OG1 3.28Å; G503-T506 WeakPolarHBondContact CA-OG1 3.47Å; G503-T506 PolarHBondContact O-OG1 2.82Å; F504-T506 PolarHBondContact O-N 3.35Å; T506-S509 PolarHBondContact O-OG 3.33Å; T506-R510 WeakPolarHBondContact O-CG 3.45Å; T506-R510 PolarHBondContact O-N 3.25Å
507	S	88.2	Confident	88.2	Confident	47 Å²	47	32 Å²	32	33%	0.329	18%	0.175	S	C	.	.	H	α-helix	trans	-69.4	-45.5	173.3	-58.2	0	0	0	0	111.6	G503 F504 C505 S509 R510	G503-S507 PolarHBondContact O-N 3Å; G503-S507 VanDerWaalsContact O-N 3.13Å; G503-S507 PolarHBondContact O-OG 3.44Å; F504-S507 WeakPolarHBondContact O-CB 3.26Å; F504-S507 PolarHBondContact O-N 3.29Å; C505-S507 VanDerWaalsContact C-N 3.26Å; C505-S507 PolarHBondContact O-N 2.92Å; S507-S509 VanDerWaalsContact C-N 3.26Å; S507-S509 PolarHBondContact O-N 3.38Å; S507-R510 PolarHBondContact O-N 3.49Å; S507-R510 VanDerWaalsContact O-N 3.08Å
508	F	92	Very high	89.1	Confident	69 Å²	69	35.4 Å²	35.4	30%	0.303	19%	0.19	S	C	.	.	H	α-helix	trans	-62.5	-31.7	174.1	-83.2	-82.8	0	0	0	112.9	W358 F504 C505 R510 I511 G512	W358-F508 HydrophobicContact CB-CB 4.23Å; W358-F508 HydrophobicContact CB-CD1 4.16Å; W358-F508 HydrophobicContact CB-CD2 3.54Å; W358-F508 HydrophobicContact CB-CE1 4.44Å; W358-F508 HydrophobicContact CB-CE2 3.86Å; W358-F508 HydrophobicContact CB-CG 3.72Å; W358-F508 HydrophobicContact CB-CZ 4.31Å; W358-F508 AromaticContact CD1-CD2 3.9Å; W358-F508 AromaticContact CD2-CD2 3.83Å; W358-F508 HydrophobicContact CD2-CD2 3.83Å; W358-F508 AromaticContact CD2-CE2 3.39Å; W358-F508 HydrophobicContact CD2-CE2 3.39Å; W358-F508 HydrophobicContact CD2-CZ 4.06Å; W358-F508 HydrophobicContact CE3-CD2 4.3Å; W358-F508 AromaticContact CE3-CE2 3.46Å; W358-F508 HydrophobicContact CE3-CE2 3.46Å; W358-F508 VanDerWaalsContact CE3-CE2 3.46Å; W358-F508 AromaticContact CE3-CZ 3.67Å; W358-F508 HydrophobicContact CE3-CZ 3.67Å; W358-F508 AromaticContact CG-CD2 3.45Å; W358-F508 HydrophobicContact CG-CD2 3.45Å; W358-F508 VanDerWaalsContact CG-CD2 3.45Å; W358-F508 AromaticContact CG-CE2 3.56Å; W358-F508 HydrophobicContact CG-CE2 3.56Å; W358-F508 HydrophobicContact CG-CG 4.16Å; W358-F508 HydrophobicContact CG-CZ 4.33Å; W358-F508 HydrophobicContact CZ3-CE2 4.22Å; W358-F508 HydrophobicContact CZ3-CZ 4.38Å; W358-F508 WeakPolarHBondContact O-CB 3.34Å; F504-F508 WeakPolarHBondContact O-CD2 3.45Å; F504-F508 PolarHBondContact O-N 3.29Å; C505-F508 PolarHBondContact O-N 3.18Å; F508-R510 VanDerWaalsContact C-N 3.3Å; F508-R510 PolarHBondContact O-N 2.8Å; F508-I511 HydrophobicContact CD1-CD1 3.97Å; F508-I511 HydrophobicContact CE1-CD1 4.33Å; F508-I511 WeakPolarHBondContact O-CB 3.39Å; F508-I511 PolarHBondContact O-N 3.21Å; F508-G512 PolarHBondContact O-N 3.24Å
509	S	92.8	Very high	89.9	Confident	3 Å²	3	34.8 Å²	34.8	2%	0.021	19%	0.19	C	C	.	.	H	α-helix	trans	-62.2	-36.2	173.1	100.7	0	0	0	0	112.1	W361 S365 C505 T506 S507 I511 G512 G513	W361-S509 WeakPolarHBondContact O-CA 3.37Å; W361-S509 WeakPolarHBondContact O-CB 3.42Å; S365-S509 WeakPolarHBondContact CB-O 3.28Å; S365-S509 PolarHBondContact OG-O 3.3Å; C505-S509 PolarHBondContact O-N 2.83Å; T506-S509 PolarHBondContact O-OG 3.33Å; S507-S509 VanDerWaalsContact C-N 3.26Å; S507-S509 PolarHBondContact O-N 3.38Å; S509-I511 VanDerWaalsContact C-N 3.29Å; S509-I511 PolarHBondContact O-N 3.17Å; S509-G512 PolarHBondContact O-N 3.13Å; S509-G512 VanDerWaalsContact O-N 3.1Å; S509-G513 PolarHBondContact O-N 3.37Å; S509-G513 VanDerWaalsContact O-N 3.14Å
510	R	90.9	Very high	90.8	Very high	27 Å²	27	30.7 Å²	30.7	10%	0.102	16%	0.162	C	C	.	.	H	α-helix	trans	-64.8	-32.7	175.6	-54.3	-50.3	169.1	178.7	-2.8	112.5	F170 M171 T506 S507 F508 G512 G513 M514	F170-R510 VanDerWaalsContact CE1-CZ 3.44Å; M171-R510 HydrophobicContact CB-CB 4.17Å; T506-R510 WeakPolarHBondContact O-CG 3.45Å; T506-R510 PolarHBondContact O-N 3.25Å; S507-R510 PolarHBondContact O-N 3.49Å; S507-R510 VanDerWaalsContact O-N 3.08Å; F508-R510 VanDerWaalsContact C-N 3.3Å; F508-R510 PolarHBondContact O-N 2.8Å; R510-G512 VanDerWaalsContact C-N 3.3Å; R510-G512 PolarHBondContact O-N 3.43Å; R510-G513 CarbonylContact O-C 3.58Å; R510-G513 PolarHBondContact O-N 3.03Å; R510-G513 VanDerWaalsContact O-N 3.17Å; R510-M514 HydrophobicContact CB-CE 4.25Å; R510-M514 WeakPolarHBondContact O-CE 3.15Å; R510-M514 PolarHBondContact O-N 3.27Å
511	I	94.4	Very high	91.3	Very high	62 Å²	62	27.9 Å²	27.9	32%	0.318	15%	0.147	S	C	.	.	H	α-helix	trans	-62.1	-39.5	173.1	-51.5	177.1	0	0	0	110.7	M171 F362 F508 S509 G513 M514 I515	M171-I511 HydrophobicContact SD-CG1 4.34Å; F362-I511 HydrophobicContact CD2-CB 4.11Å; F362-I511 HydrophobicContact CD2-CG2 4.19Å; F362-I511 HydrophobicContact CE2-CB 4.37Å; F362-I511 HydrophobicContact CE2-CG2 4.02Å; F508-I511 HydrophobicContact CD1-CD1 3.97Å; F508-I511 HydrophobicContact CE1-CD1 4.33Å; F508-I511 WeakPolarHBondContact O-CB 3.39Å; F508-I511 PolarHBondContact O-N 3.21Å; S509-I511 VanDerWaalsContact C-N 3.29Å; S509-I511 PolarHBondContact O-N 3.17Å; I511-G513 PolarHBondContact O-N 3.09Å; I511-M514 HydrophobicContact CG1-CE 4.17Å; I511-M514 PolarHBondContact O-N 3.12Å; I511-I515 HydrophobicContact CG2-CD1 4.16Å; I511-I515 WeakPolarHBondContact O-CG1 3.36Å; I511-I515 PolarHBondContact O-N 3.41Å; I511-I515 VanDerWaalsContact O-N 3.14Å
512	G	95.1	Very high	91.5	Very high	0 Å²	0	30 Å²	30	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-60.7	-43.2	172.6	0	0	0	0	0	112.7	F362 F508 S509 R510 M514 I515 A516	F362-G512 VanDerWaalsContact CD2-N 3.3Å; F362-G512 VanDerWaalsContact CE2-CA 3.45Å; F508-G512 PolarHBondContact O-N 3.24Å; S509-G512 PolarHBondContact O-N 3.13Å; S509-G512 VanDerWaalsContact O-N 3.1Å; R510-G512 VanDerWaalsContact C-N 3.3Å; R510-G512 PolarHBondContact O-N 3.43Å; G512-M514 VanDerWaalsContact C-N 3.35Å; G512-M514 PolarHBondContact O-N 3.17Å; G512-I515 PolarHBondContact O-N 3.19Å; G512-A516 WeakPolarHBondContact O-CB 3.24Å; G512-A516 PolarHBondContact O-N 2.89Å
513	G	93.1	Very high	91.7	Very high	0 Å²	0	30.3 Å²	30.3	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-66.2	-30.7	174.4	0	0	0	0	0	114.1	F167 S509 R510 I511 P517	F167-G513 VanDerWaalsContact CD2-C 3.47Å; F167-G513 WeakPolarHBondContact CD2-O 3.38Å; F167-G513 WeakPolarHBondContact CE2-O 3.39Å; S509-G513 PolarHBondContact O-N 3.37Å; S509-G513 VanDerWaalsContact O-N 3.14Å; R510-G513 CarbonylContact O-C 3.58Å; R510-G513 PolarHBondContact O-N 3.03Å; R510-G513 VanDerWaalsContact O-N 3.17Å; I511-G513 PolarHBondContact O-N 3.09Å; G513-P517 WeakPolarHBondContact O-CD 3.43Å
514	M	94.8	Very high	91.8	Very high	23 Å²	23	28.9 Å²	28.9	11%	0.113	15%	0.147	C	C	.	.	H	α-helix	trans	-71.3	-34.5	174.6	-79.7	-179.4	-95.9	0	0	113.4	T164 F167 V168 M171 R510 I511 G512	T164-M514 HydrophobicContact CG2-CB 3.99Å; T164-M514 HydrophobicContact CG2-CG 4.14Å; T164-M514 VanDerWaalsContact CG2-O 3.31Å; T164-M514 WeakPolarHBondContact CG2-O 3.4Å; T164-M514 PolarHBondContact OG1-O 2.99Å; F167-M514 HydrophobicContact CB-CB 4.45Å; F167-M514 HydrophobicContact CB-CG 3.49Å; F167-M514 VanDerWaalsContact CB-CG 3.49Å; V168-M514 HydrophobicContact CB-SD 4.34Å; V168-M514 HydrophobicContact CG2-CG 4.08Å; V168-M514 HydrophobicContact CG2-SD 3.47Å; V168-M514 WeakPolarHBondContact CG2-SD 3.43Å; M171-M514 HydrophobicContact CB-CE 3.96Å; M171-M514 HydrophobicContact CE-CE 3.49Å; M171-M514 VanDerWaalsContact CE-CE 3.49Å; M171-M514 HydrophobicContact CE-SD 4.16Å; M171-M514 HydrophobicContact CG-CE 4.26Å; M171-M514 HydrophobicContact SD-CE 3.38Å; M171-M514 WeakPolarHBondContact SD-CE 3.45Å; R510-M514 HydrophobicContact CB-CE 4.25Å; R510-M514 WeakPolarHBondContact O-CE 3.15Å; R510-M514 PolarHBondContact O-N 3.27Å; I511-M514 HydrophobicContact CG1-CE 4.17Å; I511-M514 PolarHBondContact O-N 3.12Å; G512-M514 VanDerWaalsContact C-N 3.35Å; G512-M514 PolarHBondContact O-N 3.17Å
515	I	96.1	Very high	91.4	Very high	72 Å²	72	28.3 Å²	28.3	37%	0.369	15%	0.152	S	C	.	.	H	α-helix	trans	-87.4	-32.9	-176.1	-64.1	178.5	0	0	0	112	F362 F366 I511 G512 F518 I519	F362-I515 HydrophobicContact CE2-CD1 4.04Å; F362-I515 HydrophobicContact CZ-CD1 4.23Å; F366-I515 HydrophobicContact CD2-CB 4.46Å; F366-I515 HydrophobicContact CD2-CG2 4.36Å; F366-I515 HydrophobicContact CE2-CB 4.49Å; F366-I515 HydrophobicContact CE2-CG2 3.93Å; I511-I515 HydrophobicContact CG2-CD1 4.16Å; I511-I515 WeakPolarHBondContact O-CG1 3.36Å; I511-I515 PolarHBondContact O-N 3.41Å; I511-I515 VanDerWaalsContact O-N 3.14Å; G512-I515 PolarHBondContact O-N 3.19Å; I515-F518 PolarHBondContact O-N 3Å; I515-I519 HydrophobicContact CG2-CD1 4.17Å; I515-I519 HydrophobicContact CG2-CG1 4.41Å; I515-I519 PolarHBondContact O-N 2.94Å
516	A	95.6	Very high	91	Very high	0 Å²	0	38.3 Å²	38.3	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-53.4	-42.9	-178.3	0	0	0	0	0	114.8	F366 G512 F518 I519 A520 F535	F366-A516 HydrophobicContact CD2-CB 3.9Å; F366-A516 HydrophobicContact CE2-CB 4.35Å; G512-A516 WeakPolarHBondContact O-CB 3.24Å; G512-A516 PolarHBondContact O-N 2.89Å; A516-F518 PolarHBondContact O-N 3.3Å; A516-I519 PolarHBondContact O-N 3.3Å; A516-A520 VanDerWaalsContact O-CB 3.24Å; A516-A520 WeakPolarHBondContact O-CB 3.38Å; A516-A520 PolarHBondContact O-N 2.66Å; A516-F535 HydrophobicContact CB-CE1 4.13Å; A516-F535 HydrophobicContact CB-CZ 4.44Å
517	P	94.8	Very high	90.9	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-62.4	-41.1	178.2	-21.6	30.6	0	0	0	113.8	A160 S163 L373 G513 I519 A520 Q521	A160-P517 HydrophobicContact CB-CB 4.36Å; S163-P517 VanDerWaalsContact CB-CG 3.49Å; L373-P517 HydrophobicContact CD1-CB 3.84Å; L373-P517 HydrophobicContact CD1-CG 3.64Å; G513-P517 WeakPolarHBondContact O-CD 3.43Å; P517-I519 VanDerWaalsContact C-N 3.29Å; P517-I519 PolarHBondContact O-N 3.49Å; P517-A520 PolarHBondContact O-N 3.14Å; P517-Q521 VanDerWaalsContact O-CB 3.28Å; P517-Q521 WeakPolarHBondContact O-CB 3.33Å; P517-Q521 VanDerWaalsContact O-CG 3.29Å; P517-Q521 WeakPolarHBondContact O-CG 3.09Å; P517-Q521 PolarHBondContact O-N 2.96Å
518	F	94.3	Very high	90.9	Very high	75 Å²	75	37.6 Å²	37.6	33%	0.329	19%	0.185	S	C	.	.	I	π-helix	trans	-62.6	-38.2	178.4	-86.3	-86.4	0	0	0	111.9	W157 A160 L161 T164 I515 A516 V522 L523	W157-F518 HydrophobicContact CB-CE1 4.33Å; A160-F518 HydrophobicContact CB-CD1 4.06Å; A160-F518 HydrophobicContact CB-CD2 4.23Å; A160-F518 HydrophobicContact CB-CE1 4.21Å; A160-F518 HydrophobicContact CB-CE2 4.37Å; A160-F518 HydrophobicContact CB-CG 4.07Å; A160-F518 HydrophobicContact CB-CZ 4.36Å; L161-F518 HydrophobicContact CB-CZ 4.43Å; L161-F518 HydrophobicContact CD1-CZ 4.44Å; T164-F518 HydrophobicContact CG2-CD2 4.43Å; T164-F518 HydrophobicContact CG2-CE2 4.02Å; T164-F518 VanDerWaalsContact OG1-CD2 3.26Å; T164-F518 WeakPolarHBondContact OG1-CD2 3.4Å; T164-F518 VanDerWaalsContact OG1-CE2 3.31Å; T164-F518 WeakPolarHBondContact OG1-CE2 3.23Å; I515-F518 PolarHBondContact O-N 3Å; A516-F518 PolarHBondContact O-N 3.3Å; F518-V522 HydrophobicContact CD1-CG2 3.98Å; F518-V522 WeakPolarHBondContact O-CB 3.19Å; F518-V522 WeakPolarHBondContact O-CG2 3.4Å; F518-V522 PolarHBondContact O-N 3.45Å; F518-V522 VanDerWaalsContact O-N 3.16Å; F518-L523 PolarHBondContact O-N 3.3Å
519	I	94.8	Very high	90.8	Very high	32 Å²	32	39 Å²	39	16%	0.164	19%	0.194	C	C	.	.	I	π-helix	trans	-76	-44.5	177.1	-61.8	-166.2	0	0	0	111.2	F366 I515 A516 P517 L523 A531 P534 F535	F366-I519 HydrophobicContact CE2-CD1 4.03Å; F366-I519 HydrophobicContact CZ-CD1 3.84Å; I515-I519 HydrophobicContact CG2-CD1 4.17Å; I515-I519 HydrophobicContact CG2-CG1 4.41Å; I515-I519 PolarHBondContact O-N 2.94Å; A516-I519 PolarHBondContact O-N 3.3Å; P517-I519 VanDerWaalsContact C-N 3.29Å; P517-I519 PolarHBondContact O-N 3.49Å; I519-L523 HydrophobicContact CG2-CD2 4.38Å; I519-L523 WeakPolarHBondContact O-CB 3.19Å; I519-L523 PolarHBondContact O-N 3.42Å; I519-A531 VanDerWaalsContact CG2-O 3.25Å; I519-A531 WeakPolarHBondContact CG2-O 3.49Å; I519-P534 HydrophobicContact CD1-CB 3.88Å; I519-P534 HydrophobicContact CD1-CG 4.29Å; I519-P534 HydrophobicContact CG2-CB 4.21Å; I519-P534 HydrophobicContact CG2-CG 4.16Å; I519-F535 HydrophobicContact CB-CE2 4.3Å; I519-F535 HydrophobicContact CB-CZ 4.06Å; I519-F535 HydrophobicContact CG2-CD2 4.33Å; I519-F535 HydrophobicContact CG2-CE2 3.65Å; I519-F535 HydrophobicContact CG2-CZ 3.89Å
520	A	92.1	Very high	90.6	Very high	0 Å²	0	44 Å²	44	0%	0	22%	0.217	C	C	.	.	I	π-helix	trans	-70.2	-32.1	-177.5	0	0	0	0	0	114.4	L373 A516 P517 M524 F535	L373-A520 HydrophobicContact CB-CB 3.66Å; A516-A520 VanDerWaalsContact O-CB 3.24Å; A516-A520 WeakPolarHBondContact O-CB 3.38Å; A516-A520 PolarHBondContact O-N 2.66Å; P517-A520 PolarHBondContact O-N 3.14Å; A520-M524 WeakPolarHBondContact O-CB 3.25Å; A520-F535 HydrophobicContact CB-CZ 4.35Å
521	Q	89	Confident	90.6	Very high	0 Å²	0	42.7 Å²	42.7	0%	0	21%	0.212	C	C	.	.	I	π-helix	trans	-103.4	-39.3	-173.2	-48.6	-169.3	-93.5	0	0	111.9	S145 A160 S163 E377 K381 P517	S145-Q521 PolarHBondContact OG-NE2 3.05Å; A160-Q521 HydrophobicContact CB-CB 4.23Å; S163-Q521 PolarHBondContact OG-OE1 2.9Å; E377-Q521 HydrophobicContact CG-CB 4.25Å; E377-Q521 HydrophobicContact CG-CG 3.85Å; E377-Q521 WeakPolarHBondContact OE1-CG 3.45Å; E377-Q521 PolarHBondContact OE1-NE2 2.91Å; K381-Q521 PolarHBondContact NZ-O 3.24Å; P517-Q521 VanDerWaalsContact O-CB 3.28Å; P517-Q521 WeakPolarHBondContact O-CB 3.33Å; P517-Q521 VanDerWaalsContact O-CG 3.29Å; P517-Q521 WeakPolarHBondContact O-CG 3.09Å; P517-Q521 PolarHBondContact O-N 2.96Å
522	V	89.7	Confident	90.6	Very high	44 Å²	44	39.8 Å²	39.8	27%	0.267	20%	0.197	S	C	.	.	I	π-helix	trans	-90.4	-43.8	-177.3	-162.8	0	0	0	0	113.7	D156 W157 A160 F518 M524 S525	D156-V522 HydrophobicContact CB-CB 4.4Å; D156-V522 HydrophobicContact CB-CG1 4.34Å; D156-V522 HydrophobicContact CB-CG2 4.34Å; W157-V522 HydrophobicContact CB-CG1 4.46Å; W157-V522 HydrophobicContact CB-CG2 4.02Å; A160-V522 HydrophobicContact CB-CG2 3.73Å; F518-V522 HydrophobicContact CD1-CG2 3.98Å; F518-V522 WeakPolarHBondContact O-CB 3.19Å; F518-V522 WeakPolarHBondContact O-CG2 3.4Å; F518-V522 PolarHBondContact O-N 3.45Å; F518-V522 VanDerWaalsContact O-N 3.16Å; V522-M524 VanDerWaalsContact C-N 3.28Å; V522-M524 PolarHBondContact O-N 2.97Å; V522-S525 PolarHBondContact O-OG 3.22Å; V522-S525 VanDerWaalsContact O-OG 3.09Å
523	L	88.8	Confident	90.6	Very high	50 Å²	50	42.1 Å²	42.1	26%	0.262	21%	0.212	S	C	.	.	I	π-helix	trans	-75.1	-24.6	-177.8	-165.2	52.4	0	0	0	111.7	F518 I519 S525 R526 S527 Q530 A531 P534	F518-L523 PolarHBondContact O-N 3.3Å; I519-L523 HydrophobicContact CG2-CD2 4.38Å; I519-L523 WeakPolarHBondContact O-CB 3.19Å; I519-L523 PolarHBondContact O-N 3.42Å; L523-S525 VanDerWaalsContact C-N 3.34Å; L523-S525 PolarHBondContact O-N 2.89Å; L523-R526 PolarHBondContact O-N 3.03Å; L523-R526 VanDerWaalsContact O-N 3.11Å; L523-S527 PolarHBondContact O-N 3.01Å; L523-Q530 HydrophobicContact CD1-CB 4.21Å; L523-Q530 HydrophobicContact CD2-CB 4.38Å; L523-Q530 WeakPolarHBondContact CD2-O 3.44Å; L523-Q530 HydrophobicContact CG-CB 4.11Å; L523-A531 HydrophobicContact CB-CB 4.15Å; L523-A531 HydrophobicContact CG-CB 4.35Å; L523-P534 HydrophobicContact CD2-CG 4.36Å
524	M	85.8	Confident	90.7	Very high	1 Å²	1	44.1 Å²	44.1	1%	0.005	23%	0.225	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.2	-34.4	-179.9	-163.1	70.9	73.7	0	0	113.6	E377 L378 L383 A520 V522 R526 V528 A531 L532	E377-M524 HydrophobicContact CB-CG 4.38Å; L378-M524 HydrophobicContact CD2-SD 3.86Å; L378-M524 HydrophobicContact CG-CE 4.26Å; L378-M524 HydrophobicContact CG-SD 4.15Å; L383-M524 HydrophobicContact CD1-CG 3.93Å; L383-M524 WeakPolarHBondContact CD1-O 3.5Å; A520-M524 WeakPolarHBondContact O-CB 3.25Å; V522-M524 VanDerWaalsContact C-N 3.28Å; V522-M524 PolarHBondContact O-N 2.97Å; M524-R526 VanDerWaalsContact C-N 3.28Å; M524-R526 PolarHBondContact O-N 3.29Å; M524-V528 HydrophobicContact SD-CB 4.21Å; M524-V528 HydrophobicContact SD-CG1 4.04Å; M524-V528 HydrophobicContact SD-CG2 4.05Å; M524-A531 HydrophobicContact CB-CB 4.14Å; M524-A531 HydrophobicContact CE-CB 3.89Å; M524-A531 HydrophobicContact SD-CB 3.78Å; M524-L532 HydrophobicContact CE-CD2 4.17Å
525	S	79.2	Confident	90.8	Very high	57 Å²	57	43 Å²	43	40%	0.399	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-74.3	-15.9	176.3	51.3	0	0	0	0	114	D156 V522 L523	D156-S525 WeakPolarHBondContact OD2-CB 3.44Å; D156-S525 PolarHBondContact OD2-OG 3.36Å; V522-S525 PolarHBondContact O-OG 3.22Å; V522-S525 VanDerWaalsContact O-OG 3.09Å; L523-S525 VanDerWaalsContact C-N 3.34Å; L523-S525 PolarHBondContact O-N 2.89Å
526	R	83	Confident	90.9	Very high	210 Å²	210	39.9 Å²	39.9	79%	0.792	20%	0.204	S	C	*	.	T	Hydrogen-bonded Turn	trans	-85.4	-48.1	171.1	-67.2	-165.8	175.2	-149.5	-1.1	112.1	L523 M524	L523-R526 PolarHBondContact O-N 3.03Å; L523-R526 VanDerWaalsContact O-N 3.11Å; M524-R526 VanDerWaalsContact C-N 3.28Å; M524-R526 PolarHBondContact O-N 3.29Å
527	S	85.3	Confident	91	Very high	40 Å²	40	43.4 Å²	43.4	28%	0.28	23%	0.225	S	C	.	.			trans	-169.2	130.8	176.5	175.4	0	0	0	0	110.7	L523 I529 Q530 A531	L523-S527 PolarHBondContact O-N 3.01Å; S527-I529 VanDerWaalsContact C-N 3.28Å; S527-I529 PolarHBondContact O-N 3.15Å; S527-I529 PolarHBondContact OG-N 2.82Å; S527-Q530 PolarHBondContact O-N 2.98Å; S527-Q530 VanDerWaalsContact O-N 3.11Å; S527-A531 PolarHBondContact O-N 3.32Å
528	V	87.2	Confident	91.1	Very high	25 Å²	25	43.8 Å²	43.8	15%	0.152	23%	0.229	C	C	.	.	H	α-helix	trans	-56.3	-43.5	174.4	-177.2	0	0	0	0	111.4	L378 L383 N459 M524 Q530 A531 L532	L378-V528 HydrophobicContact CD2-CG1 3.77Å; L378-V528 HydrophobicContact CD2-CG2 3.88Å; L383-V528 HydrophobicContact CB-CG2 3.75Å; L383-V528 HydrophobicContact CD1-CG2 4.27Å; L383-V528 HydrophobicContact CG-CG2 4.49Å; N459-V528 WeakPolarHBondContact OD1-CG1 3.48Å; M524-V528 HydrophobicContact SD-CB 4.21Å; M524-V528 HydrophobicContact SD-CG1 4.04Å; M524-V528 HydrophobicContact SD-CG2 4.05Å; V528-Q530 VanDerWaalsContact C-N 3.32Å; V528-Q530 PolarHBondContact O-N 3.37Å; V528-A531 PolarHBondContact O-N 3.2Å; V528-A531 VanDerWaalsContact O-N 3.13Å; V528-L532 HydrophobicContact CG1-CD1 3.67Å; V528-L532 HydrophobicContact CG1-CG 4.09Å; V528-L532 WeakPolarHBondContact O-CG 3.3Å; V528-L532 PolarHBondContact O-N 2.85Å
529	I	89.2	Confident	91.3	Very high	97 Å²	97	40.2 Å²	40.2	50%	0.497	21%	0.213	S	C	.	.	H	α-helix	trans	-60.9	-43.2	178.1	-60.5	170.2	0	0	0	110.2	N459 S527 A531 T533	N459-I529 HydrophobicContact CB-CG1 4.39Å; N459-I529 WeakPolarHBondContact OD1-CA 3.47Å; N459-I529 WeakPolarHBondContact OD1-CG1 3.29Å; N459-I529 PolarHBondContact OD1-N 3.32Å; S527-I529 VanDerWaalsContact C-N 3.28Å; S527-I529 PolarHBondContact O-N 3.15Å; S527-I529 PolarHBondContact OG-N 2.82Å; I529-A531 VanDerWaalsContact C-N 3.32Å; I529-A531 PolarHBondContact O-N 3.22Å; I529-T533 VanDerWaalsContact O-CB 3.28Å; I529-T533 WeakPolarHBondContact O-CB 3.36Å; I529-T533 PolarHBondContact O-N 2.8Å; I529-T533 PolarHBondContact O-OG1 3.18Å
530	Q	88.6	Confident	91.4	Very high	108 Å²	108	41.7 Å²	41.7	51%	0.505	22%	0.223	S	C	.	.	H	α-helix	trans	-67.4	-31.7	177.7	-65.6	-178.6	0.5	0	0	112.5	L523 S527 V528 P534	L523-Q530 HydrophobicContact CD1-CB 4.21Å; L523-Q530 HydrophobicContact CD2-CB 4.38Å; L523-Q530 WeakPolarHBondContact CD2-O 3.44Å; L523-Q530 HydrophobicContact CG-CB 4.11Å; S527-Q530 PolarHBondContact O-N 2.98Å; S527-Q530 VanDerWaalsContact O-N 3.11Å; V528-Q530 VanDerWaalsContact C-N 3.32Å; V528-Q530 PolarHBondContact O-N 3.37Å; Q530-P534 WeakPolarHBondContact O-CD 3.37Å; Q530-P534 WeakPolarHBondContact O-CG 3.34Å
531	A	91.6	Very high	91.7	Very high	0 Å²	0	46 Å²	46	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-75.9	-39.1	177.2	0	0	0	0	0	113.3	I519 L523 M524 S527 V528 I529 P534 F535	I519-A531 VanDerWaalsContact CG2-O 3.25Å; I519-A531 WeakPolarHBondContact CG2-O 3.49Å; L523-A531 HydrophobicContact CB-CB 4.15Å; L523-A531 HydrophobicContact CG-CB 4.35Å; M524-A531 HydrophobicContact CB-CB 4.14Å; M524-A531 HydrophobicContact CE-CB 3.89Å; M524-A531 HydrophobicContact SD-CB 3.78Å; S527-A531 PolarHBondContact O-N 3.32Å; V528-A531 PolarHBondContact O-N 3.2Å; V528-A531 VanDerWaalsContact O-N 3.13Å; I529-A531 VanDerWaalsContact C-N 3.32Å; I529-A531 PolarHBondContact O-N 3.22Å; A531-P534 WeakPolarHBondContact O-CD 3.35Å; A531-F535 VanDerWaalsContact O-CD2 3.28Å; A531-F535 WeakPolarHBondContact O-CD2 3.48Å; A531-F535 WeakPolarHBondContact O-CE2 3.28Å
532	L	93.7	Very high	92	Very high	2 Å²	2	46 Å²	46	1%	0.01	25%	0.245	C	C	.	.	H	α-helix	trans	-82.5	-28.2	-178	-59.9	-176.9	0	0	0	113.2	F455 V458 M524 V528 F535 A536	F455-L532 HydrophobicContact CD1-CD2 4.21Å; F455-L532 WeakPolarHBondContact O-CD1 3.48Å; V458-L532 HydrophobicContact CB-CD1 4.09Å; V458-L532 HydrophobicContact CG1-CD1 3.68Å; M524-L532 HydrophobicContact CE-CD2 4.17Å; V528-L532 HydrophobicContact CG1-CD1 3.67Å; V528-L532 HydrophobicContact CG1-CG 4.09Å; V528-L532 WeakPolarHBondContact O-CG 3.3Å; V528-L532 PolarHBondContact O-N 2.85Å; L532-F535 HydrophobicContact CD2-CD2 4.44Å; L532-F535 PolarHBondContact O-N 3.42Å; L532-A536 PolarHBondContact O-N 3Å; L532-A536 VanDerWaalsContact O-N 3.11Å
533	T	95.1	Very high	92.4	Very high	49 Å²	49	44 Å²	44	30%	0.301	23%	0.233	S	C	.	.	H	α-helix	trans	-56.1	-46.8	178.5	-61.7	0	0	0	0	113.4	I529 F535 A536 V537	I529-T533 VanDerWaalsContact O-CB 3.28Å; I529-T533 WeakPolarHBondContact O-CB 3.36Å; I529-T533 PolarHBondContact O-N 2.8Å; I529-T533 PolarHBondContact O-OG1 3.18Å; T533-F535 VanDerWaalsContact C-N 3.33Å; T533-F535 PolarHBondContact O-N 3.32Å; T533-A536 PolarHBondContact O-N 3.33Å; T533-V537 HydrophobicContact CG2-CG2 3.84Å; T533-V537 WeakPolarHBondContact O-CB 3.4Å; T533-V537 WeakPolarHBondContact O-CG2 3.3Å; T533-V537 PolarHBondContact O-N 3.01Å
534	P	96.6	Very high	92.7	Very high	42 Å²	42	46.8 Å²	46.8	27%	0.273	25%	0.248	S	C	.	.	H	α-helix	trans	-56.4	-40.1	175.9	-28.7	35	0	0	0	114.4	F366 I519 L523 Q530 A531 A538	F366-P534 HydrophobicContact CZ-CB 4.38Å; I519-P534 HydrophobicContact CD1-CB 3.88Å; I519-P534 HydrophobicContact CD1-CG 4.29Å; I519-P534 HydrophobicContact CG2-CB 4.21Å; I519-P534 HydrophobicContact CG2-CG 4.16Å; L523-P534 HydrophobicContact CD2-CG 4.36Å; Q530-P534 WeakPolarHBondContact O-CD 3.37Å; Q530-P534 WeakPolarHBondContact O-CG 3.34Å; A531-P534 WeakPolarHBondContact O-CD 3.35Å; P534-A538 VanDerWaalsContact O-CB 3.24Å; P534-A538 WeakPolarHBondContact O-CB 3.37Å; P534-A538 PolarHBondContact O-N 2.83Å
535	F	97.1	Very high	93.1	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-64.4	-47.2	175.6	-62.7	-68.4	0	0	0	110.6	F366 G370 F455 A516 I519 A520 A531 L532 T533 A538 C539	F366-F535 AromaticContact CD1-CD1 3.72Å; F366-F535 HydrophobicContact CD1-CD1 3.72Å; F366-F535 HydrophobicContact CD1-CE1 4.15Å; F366-F535 HydrophobicContact CD2-CD1 4.13Å; F366-F535 AromaticContact CD2-CE1 3.68Å; F366-F535 HydrophobicContact CD2-CE1 3.68Å; F366-F535 HydrophobicContact CE1-CB 4.47Å; F366-F535 AromaticContact CE1-CD1 3.36Å; F366-F535 HydrophobicContact CE1-CD1 3.36Å; F366-F535 AromaticContact CE1-CE1 3.83Å; F366-F535 HydrophobicContact CE1-CE1 3.83Å; F366-F535 HydrophobicContact CE1-CG 4.13Å; F366-F535 AromaticContact CE2-CD1 3.78Å; F366-F535 HydrophobicContact CE2-CD1 3.78Å; F366-F535 AromaticContact CE2-CE1 3.29Å; F366-F535 HydrophobicContact CE2-CE1 3.29Å; F366-F535 HydrophobicContact CE2-CZ 4.06Å; F366-F535 HydrophobicContact CG-CD1 4.08Å; F366-F535 HydrophobicContact CG-CE1 4.06Å; F366-F535 AromaticContact CZ-CD1 3.36Å; F366-F535 HydrophobicContact CZ-CD1 3.36Å; F366-F535 AromaticContact CZ-CE1 3.36Å; F366-F535 HydrophobicContact CZ-CE1 3.36Å; F366-F535 HydrophobicContact CZ-CG 4.15Å; F366-F535 HydrophobicContact CZ-CZ 4.16Å; F366-F535 VanDerWaalsContact O-CE1 3.27Å; F366-F535 WeakPolarHBondContact O-CE1 3.41Å; G370-F535 VanDerWaalsContact CA-CZ 3.45Å; F455-F535 HydrophobicContact CD1-CB 3.89Å; F455-F535 HydrophobicContact CD1-CG 4.45Å; F455-F535 HydrophobicContact CD2-CB 3.88Å; F455-F535 HydrophobicContact CE1-CB 3.82Å; F455-F535 HydrophobicContact CE1-CD2 4.2Å; F455-F535 HydrophobicContact CE1-CG 4.02Å; F455-F535 HydrophobicContact CE2-CB 3.82Å; F455-F535 HydrophobicContact CG-CB 3.92Å; F455-F535 HydrophobicContact CZ-CB 3.79Å; F455-F535 HydrophobicContact CZ-CD1 4.45Å; F455-F535 HydrophobicContact CZ-CG 4.1Å; A516-F535 HydrophobicContact CB-CE1 4.13Å; A516-F535 HydrophobicContact CB-CZ 4.44Å; I519-F535 HydrophobicContact CB-CE2 4.3Å; I519-F535 HydrophobicContact CB-CZ 4.06Å; I519-F535 HydrophobicContact CG2-CD2 4.33Å; I519-F535 HydrophobicContact CG2-CE2 3.65Å; I519-F535 HydrophobicContact CG2-CZ 3.89Å; A520-F535 HydrophobicContact CB-CZ 4.35Å; A531-F535 VanDerWaalsContact O-CD2 3.28Å; A531-F535 WeakPolarHBondContact O-CD2 3.48Å; A531-F535 WeakPolarHBondContact O-CE2 3.28Å; L532-F535 HydrophobicContact CD2-CD2 4.44Å; L532-F535 PolarHBondContact O-N 3.42Å; T533-F535 VanDerWaalsContact C-N 3.33Å; T533-F535 PolarHBondContact O-N 3.32Å; F535-A538 PolarHBondContact O-N 3.01Å; F535-C539 WeakPolarHBondContact O-CB 3.45Å; F535-C539 PolarHBondContact O-N 3.24Å; F535-C539 PolarHBondContact O-SG 3.47Å
536	A	97.1	Very high	93.7	Very high	6 Å²	6	44.6 Å²	44.6	5%	0.05	23%	0.234	C	C	.	.	H	α-helix	trans	-62.7	-45.2	177.6	0	0	0	0	0	112.9	A452 F455 M456 L532 T533 C539 V540	A452-A536 HydrophobicContact CB-CB 4.39Å; A452-A536 WeakPolarHBondContact CB-O 3.49Å; F455-A536 HydrophobicContact CB-CB 4.1Å; M456-A536 HydrophobicContact CG-CB 3.76Å; M456-A536 HydrophobicContact SD-CB 3.66Å; L532-A536 PolarHBondContact O-N 3Å; L532-A536 VanDerWaalsContact O-N 3.11Å; T533-A536 PolarHBondContact O-N 3.33Å; A536-C539 WeakPolarHBondContact O-CB 3.4Å; A536-C539 PolarHBondContact O-N 2.88Å; A536-V540 WeakPolarHBondContact O-CG2 3.48Å; A536-V540 PolarHBondContact O-N 3.29Å
537	V	97.5	Very high	94.2	Very high	73 Å²	73	40.3 Å²	40.3	44%	0.442	22%	0.222	S	C	.	.	H	α-helix	trans	-63.5	-44.9	178.6	170.4	0	0	0	0	111.4	T533 C539 V540 I541	T533-V537 HydrophobicContact CG2-CG2 3.84Å; T533-V537 WeakPolarHBondContact O-CB 3.4Å; T533-V537 WeakPolarHBondContact O-CG2 3.3Å; T533-V537 PolarHBondContact O-N 3.01Å; V537-C539 VanDerWaalsContact C-N 3.27Å; V537-C539 PolarHBondContact O-N 2.83Å; V537-V540 PolarHBondContact O-N 3.46Å; V537-I541 HydrophobicContact CG1-CD1 3.8Å; V537-I541 HydrophobicContact CG1-CG1 4.45Å; V537-I541 WeakPolarHBondContact O-CG1 3.37Å; V537-I541 PolarHBondContact O-N 3.49Å
538	A	97.6	Very high	94.5	Very high	9 Å²	9	42.6 Å²	42.6	7%	0.074	23%	0.23	C	C	.	.	H	α-helix	trans	-59.8	-40.1	174.9	0	0	0	0	0	111.6	Y359 V363 F366 P534 F535 C542	Y359-A538 PolarHBondContact OH-O 3.26Å; V363-A538 HydrophobicContact CG1-CB 4.31Å; V363-A538 HydrophobicContact CG2-CB 4.08Å; F366-A538 HydrophobicContact CD1-CB 3.96Å; F366-A538 HydrophobicContact CE1-CB 3.85Å; P534-A538 VanDerWaalsContact O-CB 3.24Å; P534-A538 WeakPolarHBondContact O-CB 3.37Å; P534-A538 PolarHBondContact O-N 2.83Å; F535-A538 PolarHBondContact O-N 3.01Å; A538-C542 WeakPolarHBondContact O-CB 3.36Å; A538-C542 PolarHBondContact O-N 3.33Å
539	C	97.7	Very high	94.7	Very high	0 Å²	0	41.4 Å²	41.4	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-61.4	-46.9	173.4	-67.1	0	0	0	0	112.3	Q448 A452 F535 A536 V537 C542 A543	Q448-C539 HydrophobicContact CG-CB 4.02Å; Q448-C539 WeakPolarHBondContact CG-O 3.39Å; Q448-C539 PolarHBondContact NE2-SG 3.41Å; A452-C539 HydrophobicContact CB-CB 3.63Å; F535-C539 WeakPolarHBondContact O-CB 3.45Å; F535-C539 PolarHBondContact O-N 3.24Å; F535-C539 PolarHBondContact O-SG 3.47Å; A536-C539 WeakPolarHBondContact O-CB 3.4Å; A536-C539 PolarHBondContact O-N 2.88Å; V537-C539 VanDerWaalsContact C-N 3.27Å; V537-C539 PolarHBondContact O-N 2.83Å; C539-C542 CarbonylContact O-C 3.55Å; C539-C542 WeakPolarHBondContact O-CB 3.31Å; C539-C542 PolarHBondContact O-N 3.4Å; C539-A543 PolarHBondContact O-N 2.95Å
540	V	97.9	Very high	94.3	Very high	63 Å²	63	40 Å²	40	38%	0.382	22%	0.221	S	C	.	.	H	α-helix	trans	-63.1	-45.5	179.2	173.6	0	0	0	0	111.9	A452 A536 V537 C542 A543 L544	A452-V540 HydrophobicContact CB-CG2 3.74Å; A536-V540 WeakPolarHBondContact O-CG2 3.48Å; A536-V540 PolarHBondContact O-N 3.29Å; V537-V540 PolarHBondContact O-N 3.46Å; V540-C542 VanDerWaalsContact C-N 3.26Å; V540-C542 PolarHBondContact O-N 2.97Å; V540-A543 WeakPolarHBondContact O-CB 3.5Å; V540-A543 PolarHBondContact O-N 3.19Å; V540-L544 PolarHBondContact O-N 3.21Å; V540-L544 VanDerWaalsContact O-N 3.09Å
541	I	97.5	Very high	94	Very high	89 Å²	89	36.7 Å²	36.7	46%	0.456	21%	0.206	S	C	.	.	H	α-helix	trans	-61.9	-39.1	176.3	-63.3	168.9	0	0	0	110.2	Y359 V537 L544 G545	Y359-I541 HydrophobicContact CE1-CB 4.19Å; Y359-I541 HydrophobicContact CE1-CG2 3.73Å; V537-I541 HydrophobicContact CG1-CD1 3.8Å; V537-I541 HydrophobicContact CG1-CG1 4.45Å; V537-I541 WeakPolarHBondContact O-CG1 3.37Å; V537-I541 PolarHBondContact O-N 3.49Å; I541-L544 PolarHBondContact O-N 3.03Å; I541-G545 PolarHBondContact O-N 2.94Å
542	C	96.8	Very high	93.7	Very high	0 Å²	0	39 Å²	39	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-67.7	-36.2	176.7	-176.3	0	0	0	0	112.3	Y359 V363 Q448 A538 C539 V540 G545 N546	Y359-C542 HydrophobicContact CD1-CB 4.18Å; Y359-C542 HydrophobicContact CE1-CB 3.78Å; V363-C542 HydrophobicContact CB-CB 3.96Å; V363-C542 HydrophobicContact CG1-CB 3.83Å; V363-C542 HydrophobicContact CG2-CB 3.95Å; Q448-C542 HydrophobicContact CG-CB 3.95Å; A538-C542 WeakPolarHBondContact O-CB 3.36Å; A538-C542 PolarHBondContact O-N 3.33Å; C539-C542 CarbonylContact O-C 3.55Å; C539-C542 WeakPolarHBondContact O-CB 3.31Å; C539-C542 PolarHBondContact O-N 3.4Å; V540-C542 VanDerWaalsContact C-N 3.26Å; V540-C542 PolarHBondContact O-N 2.97Å; C542-G545 PolarHBondContact O-N 3.18Å; C542-N546 VanDerWaalsContact O-CB 3.29Å; C542-N546 WeakPolarHBondContact O-CB 3.07Å; C542-N546 PolarHBondContact O-N 3.35Å; C542-N546 PolarHBondContact O-ND2 3Å; C542-N546 PolarHBondContact SG-ND2 2.92Å; C542-N546 VanDerWaalsContact SG-ND2 3.45Å
543	A	96.6	Very high	92.9	Very high	2 Å²	2	39.2 Å²	39.2	2%	0.017	22%	0.218	C	C	.	.	H	α-helix	trans	-62.6	-44.2	174.1	0	0	0	0	0	111.4	T445 Q448 L449 C539 V540 G545 N546 F547	T445-A543 HydrophobicContact CG2-CB 4.32Å; Q448-A543 HydrophobicContact CB-CB 4.14Å; Q448-A543 HydrophobicContact CG-CB 4.39Å; L449-A543 HydrophobicContact CD1-CB 4.46Å; L449-A543 HydrophobicContact CD2-CB 3.57Å; L449-A543 HydrophobicContact CG-CB 3.6Å; C539-A543 PolarHBondContact O-N 2.95Å; V540-A543 WeakPolarHBondContact O-CB 3.5Å; V540-A543 PolarHBondContact O-N 3.19Å; A543-G545 PolarHBondContact O-N 3.4Å; A543-N546 PolarHBondContact O-N 2.94Å; A543-F547 WeakPolarHBondContact O-CB 3.39Å; A543-F547 PolarHBondContact O-N 2.96Å
544	L	95.3	Very high	91.9	Very high	109 Å²	109	42.9 Å²	42.9	57%	0.571	23%	0.226	S	C	*	.	H	α-helix	trans	-61.7	-43	173.6	-65.7	171.9	0	0	0	111.5	V540 I541 F547 L548	V540-L544 PolarHBondContact O-N 3.21Å; V540-L544 VanDerWaalsContact O-N 3.09Å; I541-L544 PolarHBondContact O-N 3.03Å; L544-F547 PolarHBondContact O-N 3.48Å; L544-L548 WeakPolarHBondContact O-CB 3.5Å; L544-L548 VanDerWaalsContact O-CG 3.28Å; L544-L548 WeakPolarHBondContact O-CG 3.41Å; L544-L548 PolarHBondContact O-N 2.93Å
545	G	93.6	Very high	90.2	Very high	11 Å²	11	44.9 Å²	44.9	11%	0.113	26%	0.255	C	S	.	.	H	α-helix	trans	-61.9	-45	174.9	0	0	0	0	0	113.4	I541 C542 A543 L548 L549	I541-G545 PolarHBondContact O-N 2.94Å; C542-G545 PolarHBondContact O-N 3.18Å; A543-G545 PolarHBondContact O-N 3.4Å; G545-L548 CarbonylContact O-C 3.24Å; G545-L548 PolarHBondContact O-N 2.9Å; G545-L548 VanDerWaalsContact O-N 3.11Å; G545-L549 PolarHBondContact O-N 3.49Å
546	N	93.4	Very high	88.5	Confident	1 Å²	1	52.8 Å²	52.8	1%	0.005	28%	0.284	C	S	.	.	H	α-helix	trans	-62.9	-43.1	175.6	-71.1	-20.7	0	0	0	110.5	S360 R441 L444 C542 A543 L548 L549	S360-N546 PolarHBondContact OG-OD1 3.04Å; R441-N546 WeakPolarHBondContact CG-O 3.3Å; L444-N546 HydrophobicContact CB-CB 4.13Å; L444-N546 PolarHBondContact O-ND2 3.44Å; C542-N546 VanDerWaalsContact O-CB 3.29Å; C542-N546 WeakPolarHBondContact O-CB 3.07Å; C542-N546 PolarHBondContact O-N 3.35Å; C542-N546 PolarHBondContact O-ND2 3Å; C542-N546 PolarHBondContact SG-ND2 2.92Å; C542-N546 VanDerWaalsContact SG-ND2 3.45Å; A543-N546 PolarHBondContact O-N 2.94Å; N546-L548 PolarHBondContact O-N 3.29Å; N546-L549 HydrophobicContact CB-CD1 4.33Å; N546-L549 VanDerWaalsContact O-CB 3.28Å; N546-L549 WeakPolarHBondContact O-CB 3.39Å; N546-L549 WeakPolarHBondContact O-CD1 3.15Å; N546-L549 WeakPolarHBondContact O-CG 3.27Å; N546-L549 PolarHBondContact O-N 2.93Å; N546-L549 VanDerWaalsContact O-N 3.11Å
547	F	92.6	Very high	86.2	Confident	120 Å²	120	56.8 Å²	56.8	53%	0.526	32%	0.317	S	S	.	.	H	α-helix	trans	-61.7	-30.8	173.7	-174	-101.4	0	0	0	112.3	R441 T445 A543 L544 L549	R441-F547 PolarHBondContact NE-O 3.32Å; R441-F547 PolarHBondContact NH2-O 3.43Å; T445-F547 HydrophobicContact CG2-CB 4.03Å; T445-F547 HydrophobicContact CG2-CD2 4.46Å; T445-F547 PolarHBondContact OG1-N 3.08Å; A543-F547 WeakPolarHBondContact O-CB 3.39Å; A543-F547 PolarHBondContact O-N 2.96Å; L544-F547 PolarHBondContact O-N 3.48Å; F547-L549 VanDerWaalsContact C-N 3.33Å; F547-L549 PolarHBondContact O-N 3.46Å
548	L	92	Very high	84	Confident	89 Å²	89	58.3 Å²	58.3	47%	0.466	32%	0.323	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.5	5.5	176.5	-70.2	171.5	0	0	0	114.7	R352 L356 L544 G545 N546	R352-L548 PolarHBondContact NE-O 3.38Å; R352-L548 PolarHBondContact NH2-O 3.3Å; L356-L548 HydrophobicContact CD1-CB 4.49Å; L544-L548 WeakPolarHBondContact O-CB 3.5Å; L544-L548 VanDerWaalsContact O-CG 3.28Å; L544-L548 WeakPolarHBondContact O-CG 3.41Å; L544-L548 PolarHBondContact O-N 2.93Å; G545-L548 CarbonylContact O-C 3.24Å; G545-L548 PolarHBondContact O-N 2.9Å; G545-L548 VanDerWaalsContact O-N 3.11Å; N546-L548 PolarHBondContact O-N 3.29Å
549	L	90.8	Very high	81.7	Confident	0 Å²	0	62.3 Å²	62.3	0%	0	34%	0.342	C	S	.	.			trans	-64	131.4	174.4	-74.3	165.5	0	0	0	111.3	T353 L356 R441 L444 Y488 G545 N546 F547 I551	T353-L549 HydrophobicContact CG2-CD2 4.26Å; L356-L549 HydrophobicContact CB-CD2 3.7Å; L356-L549 HydrophobicContact CD1-CD2 3.95Å; L356-L549 HydrophobicContact CD1-CG 4.37Å; L356-L549 HydrophobicContact CG-CD2 4.5Å; R441-L549 WeakPolarHBondContact CD-O 3.21Å; R441-L549 HydrophobicContact CG-CB 4.32Å; R441-L549 PolarHBondContact NE-O 2.75Å; R441-L549 PolarHBondContact NH1-O 3.2Å; L444-L549 HydrophobicContact CD1-CD1 4.48Å; Y488-L549 HydrophobicContact CE1-CD1 3.72Å; Y488-L549 HydrophobicContact CE1-CD2 4.21Å; G545-L549 PolarHBondContact O-N 3.49Å; N546-L549 HydrophobicContact CB-CD1 4.33Å; N546-L549 VanDerWaalsContact O-CB 3.28Å; N546-L549 WeakPolarHBondContact O-CB 3.39Å; N546-L549 WeakPolarHBondContact O-CD1 3.15Å; N546-L549 WeakPolarHBondContact O-CG 3.27Å; N546-L549 PolarHBondContact O-N 2.93Å; N546-L549 VanDerWaalsContact O-N 3.11Å; F547-L549 VanDerWaalsContact C-N 3.33Å; F547-L549 PolarHBondContact O-N 3.46Å; L549-I551 VanDerWaalsContact C-N 3.33Å; L549-I551 PolarHBondContact O-N 3.43Å
550	P	82.3	Confident	78.7	Confident	68 Å²	68	70.1 Å²	70.1	44%	0.442	38%	0.379	S	S	.	.	S	Bend	trans	-77.8	-13.9	-172.5	29.5	-34.7	0	0	0	114.6	T353	T353-P550 VanDerWaalsContact OG1-CG 3.26Å; T353-P550 WeakPolarHBondContact OG1-CG 3.44Å
551	I	82.3	Confident	76	Confident	38 Å²	38	71.6 Å²	71.6	20%	0.195	38%	0.384	C	S	.	.			trans	-121.2	132.9	-171.3	-61.8	165.4	0	0	0	109	Y488 V492 L549 T553	Y488-I551 PolarHBondContact OH-O 3.44Å; V492-I551 HydrophobicContact CG2-CG2 4.48Å; L549-I551 VanDerWaalsContact C-N 3.33Å; L549-I551 PolarHBondContact O-N 3.43Å; I551-T553 HydrophobicContact CG2-CG2 4.22Å
552	E	83.4	Confident	72.8	Confident	48 Å²	48	76.2 Å²	76.2	22%	0.224	43%	0.425	C	S	.	.			trans	-104.2	133.8	160.9	174.8	53.7	-114	0	0	107.8	R440 R441 R554 R556	R440-E552 PolarHBondContact N-OE1 3.02Å; R440-E552 PolarHBondContact N-OE2 2.84Å; R441-E552 WeakPolarHBondContact CB-OE2 3.2Å; R441-E552 PolarHBondContact N-OE2 3.03Å; E552-R554 HydrophobicContact CG-CB 4.07Å; E552-R554 WeakPolarHBondContact OE1-CB 3.27Å; E552-R554 PolarHBondContact OE1-N 2.85Å; E552-R556 WeakPolarHBondContact O-CD 3.03Å; E552-R556 PolarHBondContact O-NE 2.88Å
553	T	77.9	Confident	71.6	Confident	7 Å²	7	80.1 Å²	80.1	4%	0.043	45%	0.446	C	S	.	.			trans	-99.1	-14.2	-172.9	55.1	0	0	0	0	113.3	R440 Y488 E491 V492 I551 G555 R556	R440-T553 WeakPolarHBondContact CD-OG1 3.4Å; R440-T553 WeakPolarHBondContact CG-OG1 3.11Å; Y488-T553 HydrophobicContact CD2-CG2 3.86Å; Y488-T553 HydrophobicContact CE2-CG2 3.8Å; E491-T553 HydrophobicContact CB-CG2 3.69Å; E491-T553 WeakPolarHBondContact OE2-CB 3.42Å; E491-T553 PolarHBondContact OE2-OG1 3.42Å; V492-T553 HydrophobicContact CG2-CG2 3.65Å; I551-T553 HydrophobicContact CG2-CG2 4.22Å; T553-G555 PolarHBondContact O-N 3.37Å; T553-R556 PolarHBondContact O-N 2.03Å; T553-R556 VanDerWaalsContact O-N 3.14Å
554	R	74.1	Confident	70.3	Confident	126 Å²	126	84.2 Å²	84.2	48%	0.475	47%	0.468	S	S	.	.	T	Hydrogen-bonded Turn	trans	-48.9	124.4	176	-172.6	-171.7	-175	-174.3	2.7	111.7	N436 V437 E552 R556	N436-R554 VanDerWaalsContact O-CZ 3.24Å; N436-R554 PolarHBondContact O-NE 2.92Å; N436-R554 VanDerWaalsContact O-NE 3.17Å; N436-R554 PolarHBondContact O-NH2 2.79Å; V437-R554 PolarHBondContact O-NH1 2.96Å; V437-R554 PolarHBondContact O-NH2 3.16Å; E552-R554 HydrophobicContact CG-CB 4.07Å; E552-R554 WeakPolarHBondContact OE1-CB 3.27Å; E552-R554 PolarHBondContact OE1-N 2.85Å; R554-R556 PolarHBondContact O-N 3.25Å
555	G	60	Low	68.9	Low	84 Å²	84	82.8 Å²	82.8	87%	0.866	46%	0.463	S	S	*	.	T	Hydrogen-bonded Turn	trans	72.7	2.3	174.1	0	0	0	0	0	115.5	T553	T553-G555 PolarHBondContact O-N 3.37Å
556	R	62.3	Low	67.4	Low	166 Å²	166	87 Å²	87	63%	0.626	48%	0.483	S	S	*	.	P	Polyproline II helix	trans	-80.8	135.5	173.7	-63.3	-170.1	-179.7	-156.2	-2.5	110.3	E552 T553 R554	E552-R556 WeakPolarHBondContact O-CD 3.03Å; E552-R556 PolarHBondContact O-NE 2.88Å; T553-R556 PolarHBondContact O-N 2.03Å; T553-R556 VanDerWaalsContact O-N 3.14Å; R554-R556 PolarHBondContact O-N 3.25Å
557	A	47.7	Very low	65.8	Low	89 Å²	89	92.4 Å²	92.4	74%	0.736	51%	0.513	S	S	*	.	P	Polyproline II helix	trans	-59.3	148.1	162.1	0	0	0	0	0	109.5	L559	A557-L559 PolarHBondContact O-N 2.86Å
558	L	51.5	Low	64	Low	106 Å²	106	90.5 Å²	90.5	56%	0.555	51%	0.512	S	S	*	.	P	Polyproline II helix	trans	-58.4	133.6	173.4	-70.6	172.2	0	0	0	109	Q560	L558-Q560 VanDerWaalsContact C-N 3.26Å; L558-Q560 PolarHBondContact O-N 3.07Å
559	L	50.2	Low	62	Low	92 Å²	92	90.6 Å²	90.6	48%	0.482	52%	0.516	S	S	.	.			trans	-64.8	87.8	173.7	-67.3	170.1	0	0	0	109.9	P494 T495 A557	P494-L559 HydrophobicContact CB-CB 4.3Å; T495-L559 PolarHBondContact OG1-O 2.98Å; A557-L559 PolarHBondContact O-N 2.86Å
560	Q	35.3	Very low	59.8	Low	165 Å²	165	97.6 Å²	97.6	77%	0.771	56%	0.555	S	S	*	*			trans	-75.3	138.3	154.3	-71	173.8	-41.9	0	0	106.8	L558 S562	L558-Q560 VanDerWaalsContact C-N 3.26Å; L558-Q560 PolarHBondContact O-N 3.07Å; Q560-S562 PolarHBondContact O-N 3.36Å
561	N	40	Very low	57.9	Low	93 Å²	93	100.1 Å²	100.1	50%	0.497	57%	0.565	S	S	.	*			trans	-74.1	131.7	-176.4	-45.7	-44.1	0	0	0	109.5	I496	I496-N561 WeakPolarHBondContact CD1-ND2 3.3Å; I496-N561 WeakPolarHBondContact CG1-ND2 3.27Å
562	S	30.2	Very low	55.7	Low	187 Å²	187	105.7 Å²	105.7	100%	1.308	60%	0.598	S	S	*	*			trans	-69.8	0	144	56.9	0	0	0	0	109.6	Q560	Q560-S562 PolarHBondContact O-N 3.36Å

Retrieved 562 of 562 residues in 220.2 ms (Link to these results)

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