A0A087Y6C1_POEFO Loading...

Secernin 3

AlphaFold DB , UniProt , Accession A0A087Y6C1, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 418 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M37.8Very low71.1Confident201 Ų20139.5 Ų39.599%0.9920%0.203SC*.  0128.80-169.6174.2-78.800106.2M274M1-M274 HydrophobicContact SD-CG 4.22Å
2F37.6Very low73.4Confident146 Ų14636.3 Ų36.364%0.6419%0.186SC*.  trans-107.1127.4-163.7-58.8-57.1000111.2R231F2-R231 HydrophobicContact CB-CG 4.46Å
3P43.8Very low75.2Confident15 Ų1535.2 Ų35.210%0.09718%0.183CC..  trans-59.9141.6169.48.7-12.2000111.1F149 F275P3-F149 HydrophobicContact CB-CE1 4.48Å; P3-F149 HydrophobicContact CB-CE2 4.18Å; P3-F149 HydrophobicContact CB-CZ 3.78Å; P3-F149 HydrophobicContact CG-CD2 3.91Å; P3-F149 HydrophobicContact CG-CE1 4.02Å; P3-F149 HydrophobicContact CG-CE2 3Å; P3-F149 HydrophobicContact CG-CZ 3.06Å; P3-F275 HydrophobicContact CB-CD1 4.01Å; P3-F275 HydrophobicContact CB-CD2 4.16Å; P3-F275 HydrophobicContact CB-CE1 3.62Å; P3-F275 HydrophobicContact CB-CE2 3.78Å; P3-F275 HydrophobicContact CB-CG 4.27Å; P3-F275 HydrophobicContact CB-CZ 3.49Å; P3-F275 VanDerWaalsContact CB-CZ 3.49Å; P3-F275 HydrophobicContact CG-CE2 4.39Å; P3-F275 HydrophobicContact CG-CZ 4.08Å
4S51.2Low76.8Confident50 Ų5039.3 Ų39.335%0.3521%0.213SC..  trans-111.69.6-160.246.60000117.4M271S4-M271 WeakPolarHBondContact OG-CE 3.48Å; S4-M271 PolarHBondContact OG-SD 2.89Å
5S59.3Low78.1Confident13 Ų1336.7 Ų36.79%0.09120%0.199CC..  trans111.8160.7164.6-59.70000114.9D28 N187 R238 M271S5-D28 WeakPolarHBondContact O-CB 3.41Å; S5-N187 VanDerWaalsContact C-OD1 3.3Å; S5-N187 WeakPolarHBondContact CA-OD1 3.34Å; S5-N187 WeakPolarHBondContact CB-OD1 3.36Å; S5-N187 WeakPolarHBondContact OG-CB 3.43Å; S5-N187 PolarHBondContact OG-OD1 2.97Å; S5-R238 PolarHBondContact O-NH1 3.36Å; S5-R238 VanDerWaalsContact O-NH1 3.14Å; S5-R238 PolarHBondContact O-NH2 3.24Å; S5-M271 VanDerWaalsContact O-SD 3.39Å
6C71.9Confident79.3Confident9 Ų934.8 Ų34.86%0.06119%0.189CC..  trans-120.8165.9157.42.10000111.6N26 D28 E92 N187 R238C6-N26 WeakPolarHBondContact CB-O 3.34Å; C6-D28 WeakPolarHBondContact CA-OD2 3.34Å; C6-D28 HydrophobicContact CB-CB 3.82Å; C6-D28 PolarHBondContact SG-N 2.88Å; C6-E92 WeakPolarHBondContact CA-OE2 2.9Å; C6-E92 WeakPolarHBondContact CB-OE2 3.4Å; C6-E92 PolarHBondContact N-OE2 2.98Å; C6-E92 PolarHBondContact SG-OE2 3.21Å; C6-N187 PolarHBondContact N-OD1 3.17Å; C6-N187 PolarHBondContact O-OD1 3.24Å; C6-R238 PolarHBondContact O-NH2 3.46Å
7D89.8Confident80.1Confident0 Ų038.9 Ų38.90%021%0.207CC..EExtended strand (participates in β ladder)trans-131.6136.8-178.2-57.6-60.2000112F9 K25 N26 E92 S186 R238 I269D7-F9 HydrophobicContact CB-CE2 3.51Å; D7-F9 HydrophobicContact CB-CZ 3.59Å; D7-K25 WeakPolarHBondContact O-CA 3.42Å; D7-N26 PolarHBondContact O-N 3.25Å; D7-E92 WeakPolarHBondContact CA-OE1 3.36Å; D7-E92 PolarHBondContact N-OE1 2.87Å; D7-S186 VanDerWaalsContact OD1-CB 3.3Å; D7-S186 WeakPolarHBondContact OD1-CB 3.48Å; D7-S186 PolarHBondContact OD1-OG 2.81Å; D7-R238 IonicContact OD1-CZ 2.92Å; D7-R238 IonicContact OD1-NE 2.94Å; D7-R238 PolarHBondContact OD1-NE 3.09Å; D7-R238 IonicContact OD1-NH2 3.38Å; D7-R238 PolarHBondContact OD1-NH2 3.37Å; D7-R238 IonicContact OD2-CZ 3.91Å; D7-R238 IonicContact OD2-NE 2.82Å; D7-R238 PolarHBondContact OD2-NE 3.24Å; D7-R238 IonicContact OD2-NH1 3.68Å; D7-R238 IonicContact OD2-NH2 3.18Å; D7-R238 PolarHBondContact OD2-NH2 3.41Å; D7-I269 HydrophobicContact CB-CG2 4.47Å; D7-I269 WeakPolarHBondContact OD2-CA 3.49Å
8T95.1Very high80.5Confident0 Ų038.9 Ų38.90%022%0.218CC..EExtended strand (participates in β ladder)trans-129.5136.4179.6-56.60000110.5F23 G24 K25 E92 L156 N184 I185T8-F23 HydrophobicContact CG2-CE1 4.19Å; T8-F23 HydrophobicContact CG2-CE2 3.69Å; T8-F23 HydrophobicContact CG2-CZ 3.37Å; T8-G24 CarbonylContact C-O 3.5Å; T8-G24 WeakPolarHBondContact CA-O 3.15Å; T8-K25 HydrophobicContact CG2-CB 4.08Å; T8-K25 WeakPolarHBondContact OG1-CG 3.46Å; T8-E92 PolarHBondContact N-OE1 2.71Å; T8-E92 PolarHBondContact OG1-OE1 3.06Å; T8-L156 HydrophobicContact CG2-CB 3.67Å; T8-L156 HydrophobicContact CG2-CD2 3.74Å; T8-L156 HydrophobicContact CG2-CG 4.27Å; T8-N184 CarbonylContact O-C 3.58Å; T8-N184 WeakPolarHBondContact O-CA 3.16Å; T8-N184 WeakPolarHBondContact O-CB 3.4Å; T8-I185 PolarHBondContact N-O 3.26Å; T8-I185 VanDerWaalsContact N-O 3.14Å; T8-I185 PolarHBondContact O-N 2.71Å
9F98.3Very high81.3Confident0 Ų043.9 Ų43.90%024%0.239CC..EExtended strand (participates in β ladder)trans-132.4148.3-169.5-53.3-93.3000111.1D7 F23 G24 L156 R183 N184 L246 M258 I261 L262 I269D7-F9 HydrophobicContact CB-CE2 3.51Å; D7-F9 HydrophobicContact CB-CZ 3.59Å; F9-F23 CarbonylContact O-C 3.56Å; F9-F23 WeakPolarHBondContact O-CA 3.47Å; F9-G24 PolarHBondContact N-O 3.43Å; F9-G24 PolarHBondContact O-N 2.99Å; F9-L156 VanDerWaalsContact C-CD2 3.47Å; F9-R183 CarbonylContact C-O 3.5Å; F9-R183 WeakPolarHBondContact CA-O 3.32Å; F9-N184 HydrophobicContact CD1-CB 3.48Å; F9-N184 VanDerWaalsContact CD1-CB 3.48Å; F9-N184 HydrophobicContact CE1-CB 3.81Å; F9-N184 HydrophobicContact CG-CB 4.27Å; F9-L246 HydrophobicContact CD1-CD1 3.75Å; F9-L246 HydrophobicContact CD1-CD2 4.42Å; F9-L246 HydrophobicContact CD1-CG 4.1Å; F9-M258 HydrophobicContact CB-CE 3.79Å; F9-M258 HydrophobicContact CB-SD 3.65Å; F9-M258 HydrophobicContact CD2-SD 4.39Å; F9-M258 HydrophobicContact CG-SD 4.14Å; F9-I261 HydrophobicContact CD1-CG2 4.44Å; F9-I261 HydrophobicContact CE1-CG2 4.05Å; F9-I261 HydrophobicContact CE2-CG2 4.15Å; F9-I261 HydrophobicContact CZ-CG2 3.91Å; F9-L262 HydrophobicContact CD2-CD2 3.81Å; F9-L262 HydrophobicContact CE2-CD2 3.75Å; F9-I269 HydrophobicContact CE1-CD1 4.42Å; F9-I269 HydrophobicContact CE2-CG2 4.13Å; F9-I269 HydrophobicContact CZ-CD1 3.8Å; F9-I269 HydrophobicContact CZ-CG1 4.21Å; F9-I269 HydrophobicContact CZ-CG2 4.17Å
10V98.6Very high82Confident0 Ų044.1 Ų44.10%024%0.236CC..EExtended strand (participates in β ladder)trans-140.7142167.771.80000110.3L12 I21 I22 F23 L156 A163 Y182 R183V10-L12 HydrophobicContact CB-CD1 4.39Å; V10-L12 HydrophobicContact CG1-CD1 3.86Å; V10-L12 HydrophobicContact CG2-CD1 3.71Å; V10-L12 HydrophobicContact CG2-CG 4.46Å; V10-I21 HydrophobicContact CG2-CG2 3.93Å; V10-I22 CarbonylContact C-O 3.58Å; V10-I22 VanDerWaalsContact CA-O 3.28Å; V10-I22 WeakPolarHBondContact CA-O 3.49Å; V10-F23 HydrophobicContact CB-CD2 4.5Å; V10-L156 HydrophobicContact CB-CD2 3.81Å; V10-L156 HydrophobicContact CB-CG 4.47Å; V10-L156 HydrophobicContact CG1-CD1 4.11Å; V10-L156 HydrophobicContact CG1-CD2 3.86Å; V10-L156 HydrophobicContact CG1-CG 4.34Å; V10-A163 HydrophobicContact CB-CB 4.46Å; V10-A163 HydrophobicContact CG1-CB 3.79Å; V10-A163 HydrophobicContact CG2-CB 4.11Å; V10-Y182 CarbonylContact O-C 3.53Å; V10-Y182 VanDerWaalsContact O-CA 3.23Å; V10-Y182 WeakPolarHBondContact O-CA 3.39Å; V10-Y182 WeakPolarHBondContact O-CB 3.44Å; V10-R183 HydrophobicContact CG1-CB 3.87Å; V10-R183 PolarHBondContact N-O 3.26Å; V10-R183 PolarHBondContact O-N 3.31Å
11A98.6Very high82.8Confident0 Ų042 Ų420%023%0.225CC..EExtended strand (participates in β ladder)trans-126.5130.716800000109.2I21 I22 I253A11-I21 CarbonylContact O-C 3.43Å; A11-I21 WeakPolarHBondContact O-CA 3.39Å; A11-I22 HydrophobicContact CB-CB 4.48Å; A11-I22 PolarHBondContact N-O 3.43Å; A11-I22 PolarHBondContact O-N 3.17Å; A11-I253 HydrophobicContact CB-CB 4Å; A11-I253 HydrophobicContact CB-CD1 3.64Å; A11-I253 HydrophobicContact CB-CG1 4.39Å; A11-I253 HydrophobicContact CB-CG2 3.79Å
12L98.5Very high85.7Confident1 Ų132.6 Ų32.61%0.00518%0.179CC..EExtended strand (participates in β ladder)trans-118.2157.8176.7-63.690.1000108.4V10 S15 S16 I21 A163 V178 G181V10-L12 HydrophobicContact CB-CD1 4.39Å; V10-L12 HydrophobicContact CG1-CD1 3.86Å; V10-L12 HydrophobicContact CG2-CD1 3.71Å; V10-L12 HydrophobicContact CG2-CG 4.46Å; L12-S15 WeakPolarHBondContact O-CA 3.29Å; L12-S15 WeakPolarHBondContact O-CB 3.27Å; L12-S15 PolarHBondContact O-N 3.09Å; L12-S16 PolarHBondContact O-N 3.44Å; L12-I21 HydrophobicContact CD2-CG1 4.3Å; L12-I21 HydrophobicContact CG-CG1 4.11Å; L12-A163 HydrophobicContact CD1-CB 4.03Å; L12-V178 HydrophobicContact CD1-CG1 4.25Å; L12-G181 PolarHBondContact N-O 3.01Å
13P97.4Very high88.7Confident23 Ų2325.7 Ų25.715%0.14915%0.148CC..THydrogen-bonded Turntrans-55142.5171.1-25.936000110.5S16 E180 T287P13-S16 WeakPolarHBondContact CD-OG 3.21Å; P13-E180 WeakPolarHBondContact O-CA 3.43Å; P13-E180 VanDerWaalsContact O-CB 3.26Å; P13-E180 WeakPolarHBondContact O-CB 3.29Å; P13-T287 HydrophobicContact CG-CG2 4.31Å
14P96.6Very high91.3Very high92 Ų9225 Ų2560%0.59714%0.144SC*.THydrogen-bonded Turncis-87.67.45.136.5-36.7000114.7G251P14-G251 WeakPolarHBondContact O-CA 3.47Å
15S96.9Very high93.5Very high0 Ų022.6 Ų22.60%013%0.127CC..THydrogen-bonded Turntrans-77.1-34.1-175.7-166.50000113.7L12 G181 Y182 N250 G251 H252 I253L12-S15 WeakPolarHBondContact O-CA 3.29Å; L12-S15 WeakPolarHBondContact O-CB 3.27Å; L12-S15 PolarHBondContact O-N 3.09Å; S15-G181 WeakPolarHBondContact CB-O 3.43Å; S15-Y182 WeakPolarHBondContact OG-CD1 3.48Å; S15-N250 VanDerWaalsContact CB-OD1 3.22Å; S15-N250 WeakPolarHBondContact CB-OD1 3.18Å; S15-N250 PolarHBondContact OG-OD1 2.8Å; S15-G251 CarbonylContact O-C 3.59Å; S15-G251 WeakPolarHBondContact O-CA 3.49Å; S15-G251 PolarHBondContact O-N 3.03Å; S15-H252 PolarHBondContact O-N 2.79Å; S15-H252 VanDerWaalsContact O-N 3.16Å; S15-I253 PolarHBondContact O-N 3.28Å; S15-I253 VanDerWaalsContact O-N 3.17Å; S15-I253 WeakPolarHBondContact OG-CD1 3.36Å
16S96.5Very high95.3Very high6 Ų622 Ų224%0.04212%0.123CC..BIsolated β-bridgetrans-79.8145.8174.7530000112L12 P13 R20 I253L12-S16 PolarHBondContact O-N 3.44Å; P13-S16 WeakPolarHBondContact CD-OG 3.21Å; S16-R20 WeakPolarHBondContact CB-O 3.44Å; S16-R20 PolarHBondContact OG-O 2.9Å; S16-I253 CarbonylContact C-O 3.54Å; S16-I253 WeakPolarHBondContact CA-O 3.32Å
17E93.1Very high96.5Very high106 Ų10621.5 Ų21.550%0.49512%0.12SC..SBendtrans-74.1132171.8-174.2165.1-157.200111I253 T254E17-I253 PolarHBondContact N-O 2.69Å; E17-T254 HydrophobicContact CB-CG2 3.96Å; E17-T254 WeakPolarHBondContact OE2-CG2 3.31Å
18G87.9Confident96.7Very high39 Ų3922 Ų2240%0.40212%0.122SC..SBendtrans73.2164.4-170.100000112.2R20G18-R20 PolarHBondContact O-N 3.04Å
19Q94.9Very high96.6Very high133 Ų13322.3 Ų22.362%0.62112%0.123SC*.SBendtrans-75.563.8174.9-67.6-69.4-59.800110T287Q19-T287 HydrophobicContact CB-CG2 4.44Å; Q19-T287 WeakPolarHBondContact CB-OG1 3.36Å; Q19-T287 WeakPolarHBondContact O-CB 3.46Å; Q19-T287 WeakPolarHBondContact O-CG2 3.29Å; Q19-T287 PolarHBondContact O-N 3.49Å; Q19-T287 PolarHBondContact O-OG1 3.25Å
20R96.9Very high96.4Very high47 Ų4722.8 Ų22.818%0.17713%0.127CC..EExtended strand (participates in β ladder)trans-135.2144-169.7-62.1171.2175.9-176.4-1.9110.1S16 G18 V284 V285 E387S16-R20 WeakPolarHBondContact CB-O 3.44Å; S16-R20 PolarHBondContact OG-O 2.9Å; G18-R20 PolarHBondContact O-N 3.04Å; R20-V284 HydrophobicContact CB-CG1 4.21Å; R20-V284 HydrophobicContact CG-CG1 4.36Å; R20-V285 CarbonylContact C-O 3.51Å; R20-V285 WeakPolarHBondContact CA-O 3.49Å; R20-E387 IonicContact CZ-OE2 3.31Å; R20-E387 VanDerWaalsContact CZ-OE2 3.26Å; R20-E387 VanDerWaalsContact NH1-CD 3.33Å; R20-E387 IonicContact NH1-OE1 2.78Å; R20-E387 PolarHBondContact NH1-OE1 2.87Å; R20-E387 IonicContact NH1-OE2 2.77Å; R20-E387 PolarHBondContact NH1-OE2 3.28Å; R20-E387 IonicContact NH2-OE2 2.93Å; R20-E387 PolarHBondContact NH2-OE2 3.1Å
21I98.6Very high96Very high2 Ų225 Ų251%0.0114%0.142CC..EExtended strand (participates in β ladder)trans-93.5134.2169.2-68.575.8000107.3V10 A11 L12 D159 R160 V284 V285 T287V10-I21 HydrophobicContact CG2-CG2 3.93Å; A11-I21 CarbonylContact O-C 3.43Å; A11-I21 WeakPolarHBondContact O-CA 3.39Å; L12-I21 HydrophobicContact CD2-CG1 4.3Å; L12-I21 HydrophobicContact CG-CG1 4.11Å; I21-D159 WeakPolarHBondContact CG1-O 3.22Å; I21-R160 VanDerWaalsContact CD1-C 3.43Å; I21-R160 WeakPolarHBondContact CD1-O 3.4Å; I21-V284 WeakPolarHBondContact O-CA 3.29Å; I21-V285 HydrophobicContact CB-CB 4.34Å; I21-V285 PolarHBondContact N-O 3.46Å; I21-V285 PolarHBondContact O-N 3.47Å; I21-T287 HydrophobicContact CD1-CG2 3.6Å
22I98.8Very high95.6Very high2 Ų229.5 Ų29.51%0.0117%0.166CC..EExtended strand (participates in β ladder)trans-119.7118.7177.6-61.6161.6000108.8V10 A11 I253 M258 V282 S283V10-I22 CarbonylContact C-O 3.58Å; V10-I22 VanDerWaalsContact CA-O 3.28Å; V10-I22 WeakPolarHBondContact CA-O 3.49Å; A11-I22 HydrophobicContact CB-CB 4.48Å; A11-I22 PolarHBondContact N-O 3.43Å; A11-I22 PolarHBondContact O-N 3.17Å; I22-I253 HydrophobicContact CD1-CG2 4.22Å; I22-I253 WeakPolarHBondContact CD1-O 3.37Å; I22-M258 HydrophobicContact CG2-CB 3.79Å; I22-M258 HydrophobicContact CG2-CE 3.92Å; I22-M258 HydrophobicContact CG2-CG 4.06Å; I22-V282 HydrophobicContact CG2-CG1 4.36Å; I22-S283 CarbonylContact C-O 3.56Å; I22-S283 VanDerWaalsContact CA-O 3.27Å; I22-S283 WeakPolarHBondContact CA-O 3.19Å
23F98.9Very high95.4Very high1 Ų129.6 Ų29.60%0.00417%0.166CC..EExtended strand (participates in β ladder)trans-111.5141.6178.3-179.8-86.7000109.5T8 F9 V10 K25 C88 L156 S158 M281 V282 S283T8-F23 HydrophobicContact CG2-CE1 4.19Å; T8-F23 HydrophobicContact CG2-CE2 3.69Å; T8-F23 HydrophobicContact CG2-CZ 3.37Å; F9-F23 CarbonylContact O-C 3.56Å; F9-F23 WeakPolarHBondContact O-CA 3.47Å; V10-F23 HydrophobicContact CB-CD2 4.5Å; F23-K25 HydrophobicContact CE1-CB 4.1Å; F23-C88 HydrophobicContact CB-CB 4.26Å; F23-C88 HydrophobicContact CD1-CB 4.07Å; F23-C88 HydrophobicContact CD2-CB 4.16Å; F23-C88 HydrophobicContact CE1-CB 4.48Å; F23-C88 HydrophobicContact CG-CB 3.9Å; F23-L156 HydrophobicContact CE2-CB 4.23Å; F23-L156 HydrophobicContact CE2-CD2 4.12Å; F23-L156 HydrophobicContact CE2-CG 4.1Å; F23-L156 WeakPolarHBondContact CE2-O 3.46Å; F23-S158 WeakPolarHBondContact CD2-OG 3.43Å; F23-M281 HydrophobicContact CE1-SD 4.5Å; F23-V282 CarbonylContact O-C 3.45Å; F23-V282 WeakPolarHBondContact O-CA 3.25Å; F23-S283 PolarHBondContact N-O 3.11Å; F23-S283 PolarHBondContact O-N 3.18Å
24G98.7Very high95.3Very high0 Ų028.8 Ų28.80%016%0.161CC..EExtended strand (participates in β ladder)trans-140.7139.7176.500000111.9T8 F9 M281T8-G24 CarbonylContact C-O 3.5Å; T8-G24 WeakPolarHBondContact CA-O 3.15Å; F9-G24 PolarHBondContact N-O 3.43Å; F9-G24 PolarHBondContact O-N 2.99Å; G24-M281 CarbonylContact C-O 3.59Å; G24-M281 VanDerWaalsContact CA-O 3.26Å; G24-M281 WeakPolarHBondContact CA-O 3.35Å
25K98.3Very high95.3Very high0 Ų024.4 Ų24.40%013%0.132CC..EExtended strand (participates in β ladder)trans-142140.3171.6174.7-180-176-177.40111.1D7 T8 F23 E79 M80 N91 S280 M281D7-K25 WeakPolarHBondContact O-CA 3.42Å; T8-K25 HydrophobicContact CG2-CB 4.08Å; T8-K25 WeakPolarHBondContact OG1-CG 3.46Å; F23-K25 HydrophobicContact CE1-CB 4.1Å; K25-E79 WeakPolarHBondContact CD-O 3.44Å; K25-E79 PolarHBondContact NZ-O 2.74Å; K25-E79 IonicContact NZ-OE2 3.78Å; K25-E79 PolarHBondContact NZ-OE2 3.43Å; K25-M80 HydrophobicContact CB-CB 4.47Å; K25-M80 HydrophobicContact CB-SD 3.52Å; K25-M80 VanDerWaalsContact CB-SD 3.52Å; K25-M80 HydrophobicContact CD-CB 3.72Å; K25-M80 HydrophobicContact CD-CG 4.04Å; K25-M80 HydrophobicContact CD-SD 3.6Å; K25-M80 HydrophobicContact CG-SD 3.53Å; K25-M80 VanDerWaalsContact CG-SD 3.53Å; K25-N91 VanDerWaalsContact CE-O 3.26Å; K25-N91 WeakPolarHBondContact CE-O 3.36Å; K25-N91 PolarHBondContact NZ-O 3.48Å; K25-N91 PolarHBondContact NZ-OD1 2.88Å; K25-S280 CarbonylContact O-C 3.56Å; K25-S280 VanDerWaalsContact O-CA 3.28Å; K25-S280 WeakPolarHBondContact O-CA 3.46Å; K25-M281 PolarHBondContact N-O 2.71Å; K25-M281 PolarHBondContact O-N 2.74Å
26N97.8Very high95.3Very high0 Ų025.2 Ų25.20%014%0.136CC..EExtended strand (participates in β ladder)trans-101.1138.4156.8-82.8-10000110.7C6 D7 L262 I269 T277 S280C6-N26 WeakPolarHBondContact CB-O 3.34Å; D7-N26 PolarHBondContact O-N 3.25Å; N26-L262 HydrophobicContact CB-CD2 4.47Å; N26-L262 PolarHBondContact ND2-O 3.23Å; N26-I269 PolarHBondContact ND2-O 3.19Å; N26-T277 HydrophobicContact CB-CG2 3.74Å; N26-T277 VanDerWaalsContact CG-CG2 3.46Å; N26-S280 VanDerWaalsContact OD1-CB 3.26Å; N26-S280 WeakPolarHBondContact OD1-CB 3.43Å; N26-S280 PolarHBondContact OD1-OG 2.94Å
27S96.3Very high95.4Very high0 Ų024.9 Ų24.90%013%0.134CC..EExtended strand (participates in β ladder)trans-103.8106172.4167.10000109.6R29 Q35 E79 T278 G279S27-R29 WeakPolarHBondContact OG-CG 3.5Å; S27-Q35 PolarHBondContact OG-NE2 2.91Å; S27-E79 WeakPolarHBondContact OG-CG 3.41Å; S27-T278 PolarHBondContact O-N 3.44Å; S27-T278 PolarHBondContact O-OG1 3.34Å; S27-G279 PolarHBondContact N-O 3.08Å
28D94Very high95.6Very high9 Ų920.5 Ų20.55%0.04811%0.114CC..EExtended strand (participates in β ladder)trans-98.7111-177.2-66.7-18.8000109.9S5 C6 R238 M271 M276 T277S5-D28 WeakPolarHBondContact O-CB 3.41Å; C6-D28 WeakPolarHBondContact CA-OD2 3.34Å; C6-D28 HydrophobicContact CB-CB 3.82Å; C6-D28 PolarHBondContact SG-N 2.88Å; D28-R238 IonicContact OD2-NH1 3.04Å; D28-R238 PolarHBondContact OD2-NH1 2.76Å; D28-R238 IonicContact OD2-NH2 3.96Å; D28-M271 HydrophobicContact CB-CE 3.99Å; D28-M271 HydrophobicContact CB-SD 4.46Å; D28-M276 WeakPolarHBondContact CA-O 3.15Å; D28-T277 WeakPolarHBondContact OD1-CA 3.41Å; D28-T277 VanDerWaalsContact OD1-CB 3.26Å; D28-T277 WeakPolarHBondContact OD1-CB 3.43Å; D28-T277 PolarHBondContact OD1-N 2.96Å; D28-T277 PolarHBondContact OD1-OG1 2.94Å
29R93.8Very high96.1Very high7 Ų719.9 Ų19.93%0.02610%0.101CC..EExtended strand (participates in β ladder)trans-135.3167.8-169.1-60.6-69.9-61.3172.510109.6S27 C31 E33 E79 C142 F275 M276 T278S27-R29 WeakPolarHBondContact OG-CG 3.5Å; R29-C31 PolarHBondContact O-N 3.1Å; R29-E33 HydrophobicContact CB-CB 4.45Å; R29-E33 IonicContact CZ-OE2 2.71Å; R29-E33 IonicContact NE-OE2 3.26Å; R29-E33 PolarHBondContact NE-OE2 3.15Å; R29-E33 VanDerWaalsContact NH2-CD 3.26Å; R29-E33 IonicContact NH2-OE1 2.95Å; R29-E33 PolarHBondContact NH2-OE1 3.12Å; R29-E33 IonicContact NH2-OE2 2.94Å; R29-E33 PolarHBondContact NH2-OE2 3.14Å; R29-E79 IonicContact NH1-OE1 2.64Å; R29-C142 PolarHBondContact NH1-O 3.19Å; R29-C142 PolarHBondContact NH2-O 3.04Å; R29-F275 VanDerWaalsContact O-CA 3.29Å; R29-F275 WeakPolarHBondContact O-CA 3.47Å; R29-M276 PolarHBondContact N-O 2.8Å; R29-M276 PolarHBondContact O-N 3.34Å; R29-T278 HydrophobicContact CB-CG2 3.81Å; R29-T278 WeakPolarHBondContact CB-OG1 3.48Å; R29-T278 WeakPolarHBondContact CG-OG1 3.23Å
30P93.1Very high96.3Very high11 Ų1116.9 Ų16.97%0.0719%0.086CC..EExtended strand (participates in β ladder)trans-50.7137.3170.5-24.734000110.8D32 E33 M143 M274 F275P30-D32 PolarHBondContact O-N 2.73Å; P30-E33 HydrophobicContact CB-CG 4.19Å; P30-E33 HydrophobicContact CG-CG 4.28Å; P30-E33 WeakPolarHBondContact O-CB 3.21Å; P30-E33 PolarHBondContact O-N 3.3Å; P30-M143 HydrophobicContact CG-CE 3.9Å; P30-M143 HydrophobicContact CG-CG 3.92Å; P30-M143 HydrophobicContact CG-SD 3.86Å; P30-M274 WeakPolarHBondContact CA-O 3.41Å; P30-F275 HydrophobicContact CG-CE1 3.91Å; P30-F275 HydrophobicContact CG-CE2 4.41Å; P30-F275 HydrophobicContact CG-CZ 3.79Å
31C91.4Very high96.3Very high47 Ų4718.9 Ų18.932%0.31811%0.105SC..THydrogen-bonded Turntrans-63.7-15.8-170.5600000115R29 G273 M274 M276R29-C31 PolarHBondContact O-N 3.1Å; C31-G273 WeakPolarHBondContact CB-O 3.38Å; C31-M274 PolarHBondContact N-O 2.88Å; C31-M276 HydrophobicContact CB-CB 4.47Å; C31-M276 HydrophobicContact CB-CG 3.9Å; C31-M276 HydrophobicContact CB-SD 3.53Å; C31-M276 VanDerWaalsContact CB-SD 3.53Å
32D89.6Confident96.3Very high93 Ų9320.8 Ų20.850%0.49712%0.121SC..THydrogen-bonded Turntrans-95.8-1.5176.170.8-19.3000113.6P30 K343P30-D32 PolarHBondContact O-N 2.73Å; D32-K343 IonicContact OD1-NZ 2.83Å; D32-K343 PolarHBondContact OD1-NZ 3.33Å; D32-K343 WeakPolarHBondContact OD2-CE 3.47Å; D32-K343 IonicContact OD2-NZ 2.98Å; D32-K343 PolarHBondContact OD2-NZ 3.18Å
33E93.6Very high96.2Very high3 Ų327.1 Ų27.11%0.01415%0.145CC..PPolyproline II helixtrans-80.7129.2172.1-75.1-168176.800111.5R29 P30 W74 E144R29-E33 HydrophobicContact CB-CB 4.45Å; R29-E33 IonicContact CZ-OE2 2.71Å; R29-E33 IonicContact NE-OE2 3.26Å; R29-E33 PolarHBondContact NE-OE2 3.15Å; R29-E33 VanDerWaalsContact NH2-CD 3.26Å; R29-E33 IonicContact NH2-OE1 2.95Å; R29-E33 PolarHBondContact NH2-OE1 3.12Å; R29-E33 IonicContact NH2-OE2 2.94Å; R29-E33 PolarHBondContact NH2-OE2 3.14Å; P30-E33 HydrophobicContact CB-CG 4.19Å; P30-E33 HydrophobicContact CG-CG 4.28Å; P30-E33 WeakPolarHBondContact O-CB 3.21Å; P30-E33 PolarHBondContact O-N 3.3Å; E33-W74 PolarHBondContact OE1-NE1 2.85Å; E33-E144 PolarHBondContact OE1-N 2.97Å
34V96.1Very high96.2Very high6 Ų632.7 Ų32.74%0.03618%0.175CC..PPolyproline II helixtrans-85.5130.6177.2177.10000109.6P72 A73 R346 K347 H348 F351V34-P72 CarbonylContact O-C 3.6Å; V34-P72 WeakPolarHBondContact O-CA 3.34Å; V34-A73 HydrophobicContact CB-CB 4.09Å; V34-A73 HydrophobicContact CG1-CB 4.35Å; V34-A73 WeakPolarHBondContact O-CB 3.43Å; V34-A73 PolarHBondContact O-N 3.14Å; V34-R346 HydrophobicContact CB-CB 4.39Å; V34-R346 HydrophobicContact CG2-CB 4.38Å; V34-K347 HydrophobicContact CG2-CB 4.46Å; V34-K347 HydrophobicContact CG2-CG 3.86Å; V34-H348 WeakPolarHBondContact CG1-CD2 3.48Å; V34-F351 HydrophobicContact CB-CD2 4.36Å; V34-F351 HydrophobicContact CB-CE2 4.4Å; V34-F351 HydrophobicContact CG1-CB 4.5Å; V34-F351 HydrophobicContact CG1-CD2 3.91Å; V34-F351 HydrophobicContact CG1-CE2 4.41Å; V34-F351 HydrophobicContact CG1-CG 4.28Å; V34-F351 HydrophobicContact CG2-CD1 4.34Å; V34-F351 HydrophobicContact CG2-CD2 4.11Å; V34-F351 HydrophobicContact CG2-CE1 4.28Å; V34-F351 HydrophobicContact CG2-CE2 4.02Å; V34-F351 HydrophobicContact CG2-CG 4.26Å; V34-F351 HydrophobicContact CG2-CZ 4.11Å
35Q95.3Very high96.2Very high1 Ų134.9 Ų34.91%0.00518%0.183CC..EExtended strand (participates in β ladder)trans-97.6123.1170.5-93.1-79.3-8.100110.2S27 S70 K71 T278 H348S27-Q35 PolarHBondContact OG-NE2 2.91Å; Q35-S70 PolarHBondContact OE1-OG 3.24Å; Q35-K71 CarbonylContact C-O 3.52Å; Q35-K71 WeakPolarHBondContact CA-O 3.33Å; Q35-K71 VanDerWaalsContact CD-C 3.49Å; Q35-K71 VanDerWaalsContact OE1-CA 3.3Å; Q35-K71 PolarHBondContact OE1-O 2.86Å; Q35-T278 WeakPolarHBondContact CB-O 3.44Å; Q35-T278 WeakPolarHBondContact CG-OG1 3.35Å; Q35-H348 PolarHBondContact O-NE2 3.08Å; Q35-H348 VanDerWaalsContact O-NE2 3.17Å
36E97.6Very high96.2Very high16 Ų1636.5 Ų36.58%0.07520%0.2CC..EExtended strand (participates in β ladder)trans-92.7151.7174.7-58.9178.6107.800110.6V38 S70 K71 A73 T323 S325E36-V38 HydrophobicContact CB-CG1 4.07Å; E36-S70 CarbonylContact O-C 3.52Å; E36-S70 VanDerWaalsContact O-CA 3.24Å; E36-S70 WeakPolarHBondContact O-CA 3.35Å; E36-K71 HydrophobicContact CB-CG 4.13Å; E36-K71 PolarHBondContact N-O 3.13Å; E36-K71 PolarHBondContact O-N 2.98Å; E36-K71 IonicContact OE2-NZ 2.79Å; E36-K71 PolarHBondContact OE2-NZ 3.31Å; E36-A73 HydrophobicContact CG-CB 3.91Å; E36-A73 WeakPolarHBondContact OE2-CA 3.31Å; E36-T323 WeakPolarHBondContact CA-O 3.4Å; E36-T323 VanDerWaalsContact CB-O 3.3Å; E36-T323 WeakPolarHBondContact CB-O 3.28Å; E36-S325 WeakPolarHBondContact CG-OG 3.42Å; E36-S325 WeakPolarHBondContact OE1-CA 3.43Å; E36-S325 WeakPolarHBondContact OE1-CB 3.09Å; E36-S325 PolarHBondContact OE1-N 3.45Å
37V98.6Very high96.1Very high0 Ų042.4 Ų42.40%024%0.238CC..EExtended strand (participates in β ladder)trans-115.1117.1161.5-176.30000107.8V68 L69 F297 G299 L320 T323 F404V37-V68 HydrophobicContact CG1-CG2 4.14Å; V37-L69 VanDerWaalsContact CA-O 3.31Å; V37-L69 WeakPolarHBondContact CA-O 3.47Å; V37-F297 HydrophobicContact CG1-CB 4Å; V37-F297 HydrophobicContact CG1-CD1 4.44Å; V37-F297 HydrophobicContact CG1-CD2 4.08Å; V37-F297 HydrophobicContact CG1-CG 3.93Å; V37-F297 HydrophobicContact CG2-CB 3.66Å; V37-F297 HydrophobicContact CG2-CD1 4.5Å; V37-F297 HydrophobicContact CG2-CG 4.24Å; V37-G299 VanDerWaalsContact CG2-CA 3.5Å; V37-L320 HydrophobicContact CG1-CD1 3.93Å; V37-T323 PolarHBondContact N-O 2.81Å; V37-T323 WeakPolarHBondContact O-CB 3.32Å; V37-T323 PolarHBondContact O-OG1 3.2Å; V37-F404 HydrophobicContact CB-CE1 4.27Å; V37-F404 HydrophobicContact CB-CZ 3.81Å; V37-F404 HydrophobicContact CG1-CE1 4.25Å; V37-F404 HydrophobicContact CG1-CE2 4Å; V37-F404 HydrophobicContact CG1-CZ 3.7Å; V37-F404 HydrophobicContact CG2-CZ 4.11Å
38V98.4Very high96Very high13 Ų1351.1 Ų51.18%0.07928%0.279CS..EExtended strand (participates in β ladder)trans-133.6149.1-173-66.50000111.3E36 F40 V68 L69 K71E36-V38 HydrophobicContact CB-CG1 4.07Å; V38-F40 HydrophobicContact CB-CE2 4.21Å; V38-F40 HydrophobicContact CG2-CD2 4.33Å; V38-F40 HydrophobicContact CG2-CE2 3.52Å; V38-F40 HydrophobicContact CG2-CZ 4.12Å; V38-V68 CarbonylContact O-C 3.59Å; V38-V68 WeakPolarHBondContact O-CA 3.35Å; V38-L69 HydrophobicContact CG2-CB 4.11Å; V38-L69 PolarHBondContact N-O 2.96Å; V38-L69 PolarHBondContact O-N 3.48Å; V38-K71 HydrophobicContact CG2-CD 3.83Å; V38-K71 HydrophobicContact CG2-CG 4.15Å
39H98.3Very high96.2Very high26 Ų2654.2 Ų54.212%0.1229%0.293CS..EExtended strand (participates in β ladder)trans-118.9131176.7164.3-111.7000110V67 F311 L320H39-V67 CarbonylContact C-O 3.51Å; H39-V67 WeakPolarHBondContact CA-O 3.47Å; H39-V67 PolarHBondContact CD2-O 3.17Å; H39-V67 VanDerWaalsContact CD2-O 3.3Å; H39-F311 HydrophobicContact CB-CE2 4.2Å; H39-F311 HydrophobicContact CB-CZ 4.3Å; H39-F311 AromaticContact CD2-CZ 3.71Å; H39-F311 AromaticContact CG-CZ 3.98Å; H39-L320 HydrophobicContact CB-CD1 4.17Å; H39-L320 HydrophobicContact CB-CG 4.19Å
40F97.9Very high96.4Very high70 Ų7059.5 Ų59.531%0.30732%0.316SS..EExtended strand (participates in β ladder)trans-116.7127.2173.1-63-81.6000109.2V38 A66 V67 L69V38-F40 HydrophobicContact CB-CE2 4.21Å; V38-F40 HydrophobicContact CG2-CD2 4.33Å; V38-F40 HydrophobicContact CG2-CE2 3.52Å; V38-F40 HydrophobicContact CG2-CZ 4.12Å; F40-A66 CarbonylContact O-C 3.51Å; F40-A66 WeakPolarHBondContact O-CA 3.13Å; F40-V67 HydrophobicContact CB-CG2 3.93Å; F40-V67 HydrophobicContact CD2-CG2 4.08Å; F40-V67 HydrophobicContact CG-CG2 4.49Å; F40-V67 PolarHBondContact N-O 3.18Å; F40-V67 PolarHBondContact O-N 3.14Å; F40-L69 HydrophobicContact CD2-CD1 3.98Å; F40-L69 HydrophobicContact CE2-CD1 3.95Å
41P97.7Very high96.7Very high90 Ų9059.8 Ų59.858%0.58432%0.318SS*.  trans-73.6160.717832.2-35.9000111.5
42A97.8Very high97Very high42 Ų4262 Ų6235%0.34732%0.324SS..  trans-59.3145.2170.500000110.8T64 A66 E84A42-T64 CarbonylContact C-O 3.54Å; A42-T64 WeakPolarHBondContact CA-O 3.47Å; A42-T64 WeakPolarHBondContact CB-O 3.19Å; A42-A66 HydrophobicContact CB-CB 4.26Å; A42-E84 WeakPolarHBondContact CB-OE1 3.49Å
43R97.6Very high97.4Very high134 Ų13457.6 Ų57.651%0.50630%0.3SS..EExtended strand (participates in β ladder)trans-151.3140.1-173.9-179.8169.4172.7-169.3-3.3111.9Y45 H63 T64R43-Y45 HydrophobicContact CB-CE2 3.96Å; R43-Y45 HydrophobicContact CG-CD2 4.42Å; R43-Y45 HydrophobicContact CG-CE1 4.1Å; R43-Y45 HydrophobicContact CG-CE2 3.89Å; R43-Y45 WeakPolarHBondContact O-CE2 3.42Å; R43-H63 WeakPolarHBondContact O-CA 3.16Å; R43-T64 PolarHBondContact N-O 2.78Å; R43-T64 PolarHBondContact O-N 3.49Å
44D98.4Very high97.6Very high118 Ų11857.5 Ų57.563%0.63130%0.299SS*.EExtended strand (participates in β ladder)trans-92.9145.4167.5-59.6-49.5000110.9A62 H63D44-A62 CarbonylContact C-O 3.6Å; D44-A62 WeakPolarHBondContact CA-O 3.44Å; D44-H63 IonicContact OD1-CE1 3.77Å; D44-H63 IonicContact OD1-CG 3.65Å; D44-H63 IonicContact OD1-ND1 2.76Å; D44-H63 PolarHBondContact OD1-ND1 3.27Å
45Y98.2Very high97.7Very high47 Ų4758 Ų5818%0.18430%0.301CS..  trans-125.1149.8179.7-58.8-92.5000110.6R43 Q60 V61 A62 T64R43-Y45 HydrophobicContact CB-CE2 3.96Å; R43-Y45 HydrophobicContact CG-CD2 4.42Å; R43-Y45 HydrophobicContact CG-CE1 4.1Å; R43-Y45 HydrophobicContact CG-CE2 3.89Å; R43-Y45 WeakPolarHBondContact O-CE2 3.42Å; Y45-Q60 HydrophobicContact CD1-CG 3.86Å; Y45-Q60 HydrophobicContact CD2-CG 3.79Å; Y45-Q60 HydrophobicContact CE1-CG 4.27Å; Y45-Q60 HydrophobicContact CE2-CG 4.22Å; Y45-Q60 HydrophobicContact CG-CG 3.6Å; Y45-V61 WeakPolarHBondContact CD2-O 3.36Å; Y45-A62 PolarHBondContact N-O 2.9Å; Y45-T64 HydrophobicContact CD2-CG2 4.43Å; Y45-T64 HydrophobicContact CE2-CG2 3.65Å; Y45-T64 WeakPolarHBondContact CE2-OG1 3.24Å
46G97.9Very high97.8Very high33 Ų3359.9 Ų59.934%0.3431%0.31SS..  trans-69165.7172.400000113E49G46-E49 WeakPolarHBondContact CA-OE1 3.49Å; G46-E49 PolarHBondContact N-OE1 2.92Å
47P95.9Very high97.8Very high125 Ų12564.8 Ų64.881%0.81233%0.333SS*.THydrogen-bonded Turntrans-62.6145.8175.228.7-34.7000110.8E49P47-E49 PolarHBondContact O-N 3.41Å; P47-E49 VanDerWaalsContact O-N 3.08Å
48E95Very high97.8Very high183 Ų18364.8 Ų64.886%0.85533%0.333SS*.THydrogen-bonded Turntrans62.29.2177.6-51.7179.9173.700115.1
49E98.3Very high97.8Very high73 Ų7367.7 Ų67.734%0.34135%0.346SS..  trans-61.3147.7169.6-75.8-162.2-130.300110.6G46 P47 Q60G46-E49 WeakPolarHBondContact CA-OE1 3.49Å; G46-E49 PolarHBondContact N-OE1 2.92Å; P47-E49 PolarHBondContact O-N 3.41Å; P47-E49 VanDerWaalsContact O-N 3.08Å; E49-Q60 HydrophobicContact CB-CB 4.19Å; E49-Q60 WeakPolarHBondContact O-CB 3.16Å; E49-Q60 PolarHBondContact O-N 2.92Å
50K98.3Very high97.8Very high119 Ų11967.8 Ų67.852%0.51735%0.347SS..EExtended strand (participates in β ladder)trans-119.5150.8177.7-64.4-171.4179.6-162.60110I58 E59K50-I58 VanDerWaalsContact CA-O 3.27Å; K50-I58 WeakPolarHBondContact CA-O 3.42Å; K50-I58 WeakPolarHBondContact CB-O 3.3Å; K50-E59 WeakPolarHBondContact CE-OE1 3.13Å; K50-E59 IonicContact NZ-OE1 3.1Å; K50-E59 PolarHBondContact NZ-OE1 3.37Å
51V98.3Very high97.8Very high17 Ų1766.9 Ų66.910%0.10335%0.347CS..EExtended strand (participates in β ladder)trans-112.2131.7171.160.30000109.2Q57 I58 W76V51-Q57 VanDerWaalsContact O-CA 3.32Å; V51-Q57 WeakPolarHBondContact O-CA 3.21Å; V51-I58 HydrophobicContact CG1-CD1 4.13Å; V51-I58 HydrophobicContact CG1-CG1 3.49Å; V51-I58 VanDerWaalsContact CG1-CG1 3.49Å; V51-I58 PolarHBondContact N-O 3.2Å; V51-I58 PolarHBondContact O-N 3.34Å; V51-W76 HydrophobicContact CG2-CH2 4.41Å; V51-W76 HydrophobicContact CG2-CZ2 3.62Å
52E98Very high97.8Very high94 Ų9466.2 Ų66.244%0.43935%0.348SS..EExtended strand (participates in β ladder)trans-86.9108.2172.1-169.5-179.617300109.1Q57 K335E52-Q57 HydrophobicContact CB-CG 3.78Å; E52-Q57 HydrophobicContact CG-CG 3.89Å; E52-K335 VanDerWaalsContact OE1-CD 3.31Å; E52-K335 WeakPolarHBondContact OE1-CD 3.16Å; E52-K335 VanDerWaalsContact OE1-CE 3.24Å; E52-K335 WeakPolarHBondContact OE1-CE 3.16Å; E52-K335 IonicContact OE1-NZ 3.7Å; E52-K335 PolarHBondContact OE1-NZ 2.73Å
53C98.5Very high97.9Very high0 Ų067.6 Ų67.60%035%0.347CS..  trans-79.5-158.3174-610000110.1I56 W76 L106 D110 K335C53-I56 WeakPolarHBondContact CB-O 3.48Å; C53-I56 PolarHBondContact N-O 3.31Å; C53-W76 HydrophobicContact CB-CD2 4.27Å; C53-W76 HydrophobicContact CB-CE3 3.75Å; C53-W76 HydrophobicContact CB-CZ3 4.08Å; C53-W76 VanDerWaalsContact SG-CZ3 3.55Å; C53-L106 HydrophobicContact CB-CD2 3.98Å; C53-D110 HydrophobicContact CB-CB 4.36Å; C53-K335 PolarHBondContact O-NZ 3.25Å
54T97.8Very high97.9Very high1 Ų161.3 Ų61.31%0.00632%0.324CS..SBendtrans-63.4-52.8-177.5-61.90000110.8W74 L75 W76 L107 D110 V334T54-W74 HydrophobicContact CG2-CE3 4.48Å; T54-W74 HydrophobicContact CG2-CH2 4.44Å; T54-W74 HydrophobicContact CG2-CZ3 3.74Å; T54-L75 HydrophobicContact CG2-CB 3.91Å; T54-W76 PolarHBondContact OG1-N 2.8Å; T54-L107 HydrophobicContact CG2-CD1 3.69Å; T54-D110 WeakPolarHBondContact CB-OD1 2.95Å; T54-D110 WeakPolarHBondContact CB-OD2 3.47Å; T54-D110 PolarHBondContact N-OD1 2.96Å; T54-D110 PolarHBondContact N-OD2 3.3Å; T54-D110 PolarHBondContact OG1-OD1 3.42Å; T54-D110 PolarHBondContact OG1-OD2 3.34Å; T54-V334 HydrophobicContact CG2-CG2 3.84Å
55Y97.6Very high98Very high17 Ų1758.1 Ų58.17%0.06730%0.304CS..SBendtrans-113.8-30.4-177-61.5-51000115.9E104 L107 S141 V334 F340Y55-E104 HydrophobicContact CD1-CG 4.36Å; Y55-E104 WeakPolarHBondContact CD1-OE1 3.45Å; Y55-E104 HydrophobicContact CD2-CG 4.31Å; Y55-E104 HydrophobicContact CG-CB 4.27Å; Y55-E104 HydrophobicContact CG-CG 4Å; Y55-L107 HydrophobicContact CD2-CD1 4.15Å; Y55-L107 HydrophobicContact CD2-CD2 4.15Å; Y55-L107 HydrophobicContact CD2-CG 3.95Å; Y55-L107 HydrophobicContact CE2-CD1 3.62Å; Y55-L107 HydrophobicContact CE2-CD2 3.79Å; Y55-L107 HydrophobicContact CE2-CG 3.79Å; Y55-S141 VanDerWaalsContact CE2-O 3.29Å; Y55-S141 WeakPolarHBondContact CE2-O 3.4Å; Y55-S141 VanDerWaalsContact CZ-O 3.32Å; Y55-S141 PolarHBondContact OH-O 3.13Å; Y55-V334 HydrophobicContact CD1-CG2 4.38Å; Y55-V334 HydrophobicContact CE1-CG2 3.87Å; Y55-F340 HydrophobicContact CE1-CE2 4.49Å; Y55-F340 HydrophobicContact CE1-CZ 4.23Å; Y55-F340 WeakPolarHBondContact OH-CE2 3.37Å; Y55-F340 WeakPolarHBondContact OH-CZ 3.13Å
56I98Very high98Very high39 Ų3956.2 Ų56.220%0.230%0.298CS..  trans-122.3160.3-174.968.6165.9000111.8C53 I58 L106 Y136C53-I56 WeakPolarHBondContact CB-O 3.48Å; C53-I56 PolarHBondContact N-O 3.31Å; I56-I58 HydrophobicContact CD1-CG2 3.81Å; I56-I58 HydrophobicContact CG1-CG2 4.1Å; I56-L106 HydrophobicContact CD1-CD2 3.97Å; I56-L106 HydrophobicContact CD1-CG 3.97Å; I56-L106 HydrophobicContact CG1-CD2 3.91Å; I56-L106 HydrophobicContact CG1-CG 4.41Å; I56-Y136 HydrophobicContact CD1-CD1 4.47Å
57Q98.3Very high98Very high119 Ų11954.6 Ų54.656%0.55628%0.281SS*.EExtended strand (participates in β ladder)trans-97.1138.3166.8-83.4-179.9-10.500110.5V51 E52V51-Q57 VanDerWaalsContact O-CA 3.32Å; V51-Q57 WeakPolarHBondContact O-CA 3.21Å; E52-Q57 HydrophobicContact CB-CG 3.78Å; E52-Q57 HydrophobicContact CG-CG 3.89Å
58I98.6Very high98.2Very high1 Ų148.7 Ų48.71%0.00524%0.243CC..EExtended strand (participates in β ladder)trans-126.6165.7175.368.8168.9000111.1K50 V51 I56 L106 L114 L132 Y136K50-I58 VanDerWaalsContact CA-O 3.27Å; K50-I58 WeakPolarHBondContact CA-O 3.42Å; K50-I58 WeakPolarHBondContact CB-O 3.3Å; V51-I58 HydrophobicContact CG1-CD1 4.13Å; V51-I58 HydrophobicContact CG1-CG1 3.49Å; V51-I58 VanDerWaalsContact CG1-CG1 3.49Å; V51-I58 PolarHBondContact N-O 3.2Å; V51-I58 PolarHBondContact O-N 3.34Å; I56-I58 HydrophobicContact CD1-CG2 3.81Å; I56-I58 HydrophobicContact CG1-CG2 4.1Å; I58-L106 HydrophobicContact CD1-CD2 4.48Å; I58-L106 HydrophobicContact CG2-CD2 3.97Å; I58-L114 HydrophobicContact CD1-CD1 3.66Å; I58-L114 HydrophobicContact CD1-CD2 3.87Å; I58-L114 HydrophobicContact CD1-CG 4.45Å; I58-L132 HydrophobicContact CD1-CD2 3.91Å; I58-Y136 HydrophobicContact CB-CD1 4.34Å; I58-Y136 HydrophobicContact CB-CD2 4.27Å; I58-Y136 HydrophobicContact CB-CE1 3.94Å; I58-Y136 HydrophobicContact CB-CE2 3.85Å; I58-Y136 HydrophobicContact CB-CG 4.5Å; I58-Y136 HydrophobicContact CD1-CE2 4.43Å; I58-Y136 HydrophobicContact CG2-CD1 3.64Å; I58-Y136 HydrophobicContact CG2-CD2 3.86Å; I58-Y136 HydrophobicContact CG2-CE1 3.74Å; I58-Y136 HydrophobicContact CG2-CE2 3.95Å; I58-Y136 HydrophobicContact CG2-CG 3.7Å
59E98.3Very high98.3Very high73 Ų7340 Ų4034%0.34120%0.202SC..EExtended strand (participates in β ladder)trans-65.7135.1174-56.5-56.2139.800109.9K50 R118 Y136K50-E59 WeakPolarHBondContact CE-OE1 3.13Å; K50-E59 IonicContact NZ-OE1 3.1Å; K50-E59 PolarHBondContact NZ-OE1 3.37Å; E59-R118 PolarHBondContact O-NH2 3.43Å; E59-R118 VanDerWaalsContact O-NH2 3.12Å; E59-Y136 WeakPolarHBondContact CG-OH 3.4Å; E59-Y136 PolarHBondContact N-OH 2.88Å
60Q98.1Very high98.4Very high29 Ų2936.5 Ų36.514%0.13619%0.186CC..PPolyproline II helixtrans-84.3150175.8-171.353.1-66.400110.7Y45 E49Y45-Q60 HydrophobicContact CD1-CG 3.86Å; Y45-Q60 HydrophobicContact CD2-CG 3.79Å; Y45-Q60 HydrophobicContact CE1-CG 4.27Å; Y45-Q60 HydrophobicContact CE2-CG 4.22Å; Y45-Q60 HydrophobicContact CG-CG 3.6Å; E49-Q60 HydrophobicContact CB-CB 4.19Å; E49-Q60 WeakPolarHBondContact O-CB 3.16Å; E49-Q60 PolarHBondContact O-N 2.92Å
61V98.1Very high98.3Very high51 Ų5131.4 Ų31.431%0.30916%0.164SC..PPolyproline II helixtrans-85.8157.7171-67.50000110.5Y45 H63 T64 R118Y45-V61 WeakPolarHBondContact CD2-O 3.36Å; V61-H63 WeakPolarHBondContact CG2-O 3.34Å; V61-H63 PolarHBondContact O-N 2.91Å; V61-T64 HydrophobicContact CG2-CG2 3.93Å; V61-R118 HydrophobicContact CG1-CG 4.39Å; V61-R118 HydrophobicContact CG2-CG 3.83Å
62A98.1Very high98.3Very high75 Ų7530.7 Ų30.762%0.6216%0.159SC*.SBendtrans-60.9-29.1-178.500000113.7D44 Y45D44-A62 CarbonylContact C-O 3.6Å; D44-A62 WeakPolarHBondContact CA-O 3.44Å; Y45-A62 PolarHBondContact N-O 2.9Å
63H98.6Very high98.3Very high71 Ų7126.7 Ų26.733%0.32914%0.143SC..EExtended strand (participates in β ladder)trans-141.6136.6-177.5-176.178.1000110.9R43 D44 V61 Y65R43-H63 WeakPolarHBondContact O-CA 3.16Å; D44-H63 IonicContact OD1-CE1 3.77Å; D44-H63 IonicContact OD1-CG 3.65Å; D44-H63 IonicContact OD1-ND1 2.76Å; D44-H63 PolarHBondContact OD1-ND1 3.27Å; V61-H63 WeakPolarHBondContact CG2-O 3.34Å; V61-H63 PolarHBondContact O-N 2.91Å; H63-Y65 AromaticContact CD2-CD1 3.74Å; H63-Y65 AromaticContact CD2-CE1 3.67Å; H63-Y65 AromaticContact NE2-CD1 3.6Å; H63-Y65 AromaticContact NE2-CE1 3.82Å
64T98.8Very high98.2Very high3 Ų327 Ų272%0.01814%0.144CC..EExtended strand (participates in β ladder)trans-118.3140.5167.560.30000111A42 R43 Y45 V61 E117A42-T64 CarbonylContact C-O 3.54Å; A42-T64 WeakPolarHBondContact CA-O 3.47Å; A42-T64 WeakPolarHBondContact CB-O 3.19Å; R43-T64 PolarHBondContact N-O 2.78Å; R43-T64 PolarHBondContact O-N 3.49Å; Y45-T64 HydrophobicContact CD2-CG2 4.43Å; Y45-T64 HydrophobicContact CE2-CG2 3.65Å; Y45-T64 WeakPolarHBondContact CE2-OG1 3.24Å; V61-T64 HydrophobicContact CG2-CG2 3.93Å; T64-E117 CarbonylContact C-O 3.51Å; T64-E117 WeakPolarHBondContact CA-O 3.4Å; T64-E117 HydrophobicContact CG2-CB 4.04Å
65Y98.8Very high98.1Very high50 Ų5027.3 Ų27.320%0.19615%0.145CC..  trans-74.6156.8174-56.9-51.3000112.3H63 E84 H85 E117 A119 D120H63-Y65 AromaticContact CD2-CD1 3.74Å; H63-Y65 AromaticContact CD2-CE1 3.67Å; H63-Y65 AromaticContact NE2-CD1 3.6Å; H63-Y65 AromaticContact NE2-CE1 3.82Å; Y65-E84 WeakPolarHBondContact CA-OE1 3.2Å; Y65-H85 AromaticContact CD1-CD2 3.55Å; Y65-H85 AromaticContact CD1-NE2 3.16Å; Y65-H85 WeakPolarHBondContact CD1-NE2 3.27Å; Y65-H85 AromaticContact CD2-CD2 3.74Å; Y65-H85 AromaticContact CE1-CD2 3.78Å; Y65-H85 AromaticContact CE1-NE2 3.16Å; Y65-H85 WeakPolarHBondContact CE1-NE2 3.35Å; Y65-H85 AromaticContact CE2-CD2 3.95Å; Y65-H85 AromaticContact CG-CD2 3.53Å; Y65-H85 AromaticContact CG-NE2 3.69Å; Y65-H85 AromaticContact CZ-CD2 3.95Å; Y65-H85 AromaticContact CZ-NE2 3.67Å; Y65-E117 PolarHBondContact N-O 3.09Å; Y65-A119 VanDerWaalsContact CE2-C 3.48Å; Y65-D120 HydrophobicContact CE2-CB 4.02Å
66A98.7Very high98.1Very high7 Ų728.5 Ų28.56%0.05815%0.15CC..  trans-67.6138.3172.300000110.6F40 A42 N83 E84 F313F40-A66 CarbonylContact O-C 3.51Å; F40-A66 WeakPolarHBondContact O-CA 3.13Å; A42-A66 HydrophobicContact CB-CB 4.26Å; A66-N83 CarbonylContact O-C 3.54Å; A66-N83 WeakPolarHBondContact O-CA 3.5Å; A66-N83 WeakPolarHBondContact O-CB 3.43Å; A66-E84 HydrophobicContact CB-CB 4.22Å; A66-E84 HydrophobicContact CB-CG 4.39Å; A66-E84 PolarHBondContact N-OE1 2.94Å; A66-E84 PolarHBondContact O-N 3.02Å; A66-F313 HydrophobicContact CB-CD1 4.37Å; A66-F313 HydrophobicContact CB-CE1 4.22Å
67V98.9Very high98.1Very high0 Ų026.6 Ų26.60%014%0.14CC..EExtended strand (participates in β ladder)trans-135.1146.8-177-61.80000111.8H39 F40 L69 A82 N83 L116 E117H39-V67 CarbonylContact C-O 3.51Å; H39-V67 WeakPolarHBondContact CA-O 3.47Å; H39-V67 PolarHBondContact CD2-O 3.17Å; H39-V67 VanDerWaalsContact CD2-O 3.3Å; F40-V67 HydrophobicContact CB-CG2 3.93Å; F40-V67 HydrophobicContact CD2-CG2 4.08Å; F40-V67 HydrophobicContact CG-CG2 4.49Å; F40-V67 PolarHBondContact N-O 3.18Å; F40-V67 PolarHBondContact O-N 3.14Å; V67-L69 HydrophobicContact CB-CD2 4.03Å; V67-L69 HydrophobicContact CB-CG 4.31Å; V67-L69 HydrophobicContact CG2-CD1 4.05Å; V67-L69 HydrophobicContact CG2-CD2 4.07Å; V67-L69 HydrophobicContact CG2-CG 3.93Å; V67-A82 WeakPolarHBondContact CA-O 3.43Å; V67-N83 HydrophobicContact CG1-CB 3.85Å; V67-L116 HydrophobicContact CG1-CB 3.74Å; V67-E117 HydrophobicContact CG1-CG 3.89Å; V67-E117 HydrophobicContact CG2-CG 4.11Å
68V98.9Very high98.1Very high0 Ų021 Ų210%011%0.114CC..EExtended strand (participates in β ladder)trans-115.2127.2163.4620000108.1V37 V38 G81 A82 F297 F311 F313 L320V37-V68 HydrophobicContact CG1-CG2 4.14Å; V38-V68 CarbonylContact O-C 3.59Å; V38-V68 WeakPolarHBondContact O-CA 3.35Å; V68-G81 CarbonylContact O-C 3.55Å; V68-G81 WeakPolarHBondContact O-CA 3.34Å; V68-A82 HydrophobicContact CG1-CB 4.29Å; V68-A82 PolarHBondContact N-O 2.94Å; V68-A82 PolarHBondContact O-N 3.49Å; V68-F297 HydrophobicContact CB-CE2 4.37Å; V68-F297 HydrophobicContact CB-CZ 4.48Å; V68-F297 HydrophobicContact CG1-CE2 3.74Å; V68-F297 HydrophobicContact CG1-CZ 3.78Å; V68-F297 HydrophobicContact CG2-CD2 4.32Å; V68-F297 HydrophobicContact CG2-CE2 3.68Å; V68-F297 HydrophobicContact CG2-CZ 4.02Å; V68-F311 HydrophobicContact CB-CD1 3.92Å; V68-F311 HydrophobicContact CB-CE1 3.82Å; V68-F311 HydrophobicContact CB-CG 4.4Å; V68-F311 HydrophobicContact CB-CZ 4.2Å; V68-F311 HydrophobicContact CG1-CD1 3.68Å; V68-F311 HydrophobicContact CG1-CE1 3.87Å; V68-F311 HydrophobicContact CG1-CG 4.41Å; V68-F311 HydrophobicContact CG2-CD1 4.14Å; V68-F311 HydrophobicContact CG2-CD2 4.31Å; V68-F311 HydrophobicContact CG2-CE1 4.37Å; V68-F311 HydrophobicContact CG2-CG 4.11Å; V68-F313 HydrophobicContact CB-CZ 4.26Å; V68-F313 HydrophobicContact CG1-CE2 4.08Å; V68-F313 HydrophobicContact CG1-CZ 3.75Å; V68-L320 HydrophobicContact CG2-CD1 4.45Å
69L98.8Very high98.1Very high0 Ų021 Ų210%011%0.114CC..EExtended strand (participates in β ladder)trans-125.1140.9-169.5-55.5178.2000110.5V37 V38 F40 V67 A78 M80 R113 L116V37-L69 VanDerWaalsContact CA-O 3.31Å; V37-L69 WeakPolarHBondContact CA-O 3.47Å; V38-L69 HydrophobicContact CG2-CB 4.11Å; V38-L69 PolarHBondContact N-O 2.96Å; V38-L69 PolarHBondContact O-N 3.48Å; F40-L69 HydrophobicContact CD2-CD1 3.98Å; F40-L69 HydrophobicContact CE2-CD1 3.95Å; V67-L69 HydrophobicContact CB-CD2 4.03Å; V67-L69 HydrophobicContact CB-CG 4.31Å; V67-L69 HydrophobicContact CG2-CD1 4.05Å; V67-L69 HydrophobicContact CG2-CD2 4.07Å; V67-L69 HydrophobicContact CG2-CG 3.93Å; L69-A78 HydrophobicContact CB-CB 3.91Å; L69-A78 HydrophobicContact CD1-CB 4.14Å; L69-A78 HydrophobicContact CD2-CB 3.93Å; L69-A78 HydrophobicContact CG-CB 4.21Å; L69-M80 WeakPolarHBondContact CA-O 3.27Å; L69-R113 HydrophobicContact CD1-CB 4.38Å; L69-R113 HydrophobicContact CD1-CG 3.84Å; L69-L116 HydrophobicContact CD2-CD1 3.58Å
70S98.6Very high98.2Very high0 Ų017.6 Ų17.60%010%0.098CC..EExtended strand (participates in β ladder)trans-100.4116.7157.1-165.90000108.4Q35 E36 E79 M80Q35-S70 PolarHBondContact OE1-OG 3.24Å; E36-S70 CarbonylContact O-C 3.52Å; E36-S70 VanDerWaalsContact O-CA 3.24Å; E36-S70 WeakPolarHBondContact O-CA 3.35Å; S70-E79 PolarHBondContact O-N 3.31Å; S70-M80 PolarHBondContact N-O 2.86Å; S70-M80 PolarHBondContact O-N 3.17Å; S70-M80 WeakPolarHBondContact OG-CE 2.94Å
71K97.4Very high98.2Very high13 Ų1316.2 Ų16.26%0.0579%0.091CC..EExtended strand (participates in β ladder)trans-137.9146.5-175.159.6173.6-67.8-60.50113.5Q35 E36 V38 A73 L75 G77 A78Q35-K71 CarbonylContact C-O 3.52Å; Q35-K71 WeakPolarHBondContact CA-O 3.33Å; Q35-K71 VanDerWaalsContact CD-C 3.49Å; Q35-K71 VanDerWaalsContact OE1-CA 3.3Å; Q35-K71 PolarHBondContact OE1-O 2.86Å; E36-K71 HydrophobicContact CB-CG 4.13Å; E36-K71 PolarHBondContact N-O 3.13Å; E36-K71 PolarHBondContact O-N 2.98Å; E36-K71 IonicContact OE2-NZ 2.79Å; E36-K71 PolarHBondContact OE2-NZ 3.31Å; V38-K71 HydrophobicContact CG2-CD 3.83Å; V38-K71 HydrophobicContact CG2-CG 4.15Å; K71-A73 PolarHBondContact O-N 3.46Å; K71-L75 WeakPolarHBondContact CE-O 3.39Å; K71-L75 PolarHBondContact NZ-O 2.74Å; K71-G77 WeakPolarHBondContact CB-O 3.29Å; K71-G77 WeakPolarHBondContact CE-O 3.5Å; K71-A78 HydrophobicContact CB-CB 4.13Å
72P97.2Very high98.2Very high1 Ų113.8 Ų13.81%0.0068%0.077CC..EExtended strand (participates in β ladder)trans-58.7138.5164.8-2334.1000110.4V34 W74 L75 E79V34-P72 CarbonylContact O-C 3.6Å; V34-P72 WeakPolarHBondContact O-CA 3.34Å; P72-W74 PolarHBondContact O-N 3.46Å; P72-W74 VanDerWaalsContact O-N 3.08Å; P72-L75 HydrophobicContact CB-CD2 4Å; P72-L75 HydrophobicContact CB-CG 4.02Å; P72-L75 HydrophobicContact CG-CD2 3.76Å; P72-L75 HydrophobicContact CG-CG 4.16Å; P72-L75 PolarHBondContact O-N 3Å; P72-E79 HydrophobicContact CG-CG 3.92Å
73A97.6Very high98.3Very high11 Ų1110.2 Ų10.29%0.0915%0.047CC..THydrogen-bonded Turntrans-64.9-16.5-171.200000114.6V34 E36 K71 S325 R346V34-A73 HydrophobicContact CB-CB 4.09Å; V34-A73 HydrophobicContact CG1-CB 4.35Å; V34-A73 WeakPolarHBondContact O-CB 3.43Å; V34-A73 PolarHBondContact O-N 3.14Å; E36-A73 HydrophobicContact CG-CB 3.91Å; E36-A73 WeakPolarHBondContact OE2-CA 3.31Å; K71-A73 PolarHBondContact O-N 3.46Å; A73-S325 WeakPolarHBondContact CB-OG 3.48Å; A73-R346 HydrophobicContact CB-CB 3.71Å; A73-R346 HydrophobicContact CB-CG 4.29Å; A73-R346 PolarHBondContact O-NH1 3.19Å
74W96.7Very high98.3Very high6 Ų610.4 Ų10.42%0.0235%0.048CC..THydrogen-bonded Turntrans-93.7-23.3-175.969.2-98.4000114.5E33 T54 P72 L107 E144 V334 F340E33-W74 PolarHBondContact OE1-NE1 2.85Å; T54-W74 HydrophobicContact CG2-CE3 4.48Å; T54-W74 HydrophobicContact CG2-CH2 4.44Å; T54-W74 HydrophobicContact CG2-CZ3 3.74Å; P72-W74 PolarHBondContact O-N 3.46Å; P72-W74 VanDerWaalsContact O-N 3.08Å; W74-L107 HydrophobicContact CH2-CD1 4.17Å; W74-E144 HydrophobicContact CB-CB 4.27Å; W74-E144 HydrophobicContact CB-CG 4.11Å; W74-E144 HydrophobicContact CD2-CB 3.97Å; W74-E144 HydrophobicContact CG-CB 3.73Å; W74-E144 HydrophobicContact CG-CG 4.11Å; W74-V334 HydrophobicContact CE3-CB 4.34Å; W74-V334 HydrophobicContact CE3-CG2 3.78Å; W74-V334 HydrophobicContact CZ3-CG2 3.85Å; W74-F340 AromaticContact CE3-CE1 3.9Å; W74-F340 HydrophobicContact CE3-CE1 3.9Å; W74-F340 AromaticContact CE3-CZ 3.88Å; W74-F340 HydrophobicContact CE3-CZ 3.88Å; W74-F340 HydrophobicContact CH2-CZ 4.28Å; W74-F340 HydrophobicContact CZ3-CE1 4.14Å; W74-F340 AromaticContact CZ3-CZ 3.62Å; W74-F340 HydrophobicContact CZ3-CZ 3.62Å
75L96.4Very high98.3Very high7 Ų713.7 Ų13.74%0.0376%0.063CC..SBendtrans-101.8164.5-175.565.579000112.1T54 K71 P72 G77 M109T54-L75 HydrophobicContact CG2-CB 3.91Å; K71-L75 WeakPolarHBondContact CE-O 3.39Å; K71-L75 PolarHBondContact NZ-O 2.74Å; P72-L75 HydrophobicContact CB-CD2 4Å; P72-L75 HydrophobicContact CB-CG 4.02Å; P72-L75 HydrophobicContact CG-CD2 3.76Å; P72-L75 HydrophobicContact CG-CG 4.16Å; P72-L75 PolarHBondContact O-N 3Å; L75-G77 VanDerWaalsContact CD1-N 3.31Å; L75-G77 WeakPolarHBondContact CD1-O 3.41Å; L75-M109 HydrophobicContact CD1-CB 4.09Å; L75-M109 HydrophobicContact CD2-CB 4.19Å; L75-M109 HydrophobicContact CD2-CE 3.93Å; L75-M109 HydrophobicContact CD2-CG 4.16Å
76W98.1Very high98.2Very high42 Ų4211.7 Ų11.716%0.1596%0.055CC..SBendtrans-86.1-37.5-179.7170.986.9000113.4V51 C53 T54 D110 R113 L114V51-W76 HydrophobicContact CG2-CH2 4.41Å; V51-W76 HydrophobicContact CG2-CZ2 3.62Å; C53-W76 HydrophobicContact CB-CD2 4.27Å; C53-W76 HydrophobicContact CB-CE3 3.75Å; C53-W76 HydrophobicContact CB-CZ3 4.08Å; C53-W76 VanDerWaalsContact SG-CZ3 3.55Å; T54-W76 PolarHBondContact OG1-N 2.8Å; W76-D110 HydrophobicContact CE3-CB 4.1Å; W76-D110 HydrophobicContact CZ3-CB 4.03Å; W76-R113 HydrophobicContact CH2-CB 4.37Å; W76-R113 HydrophobicContact CH2-CG 3.92Å; W76-R113 HydrophobicContact CZ2-CG 4.3Å; W76-R113 HydrophobicContact CZ3-CB 4.21Å; W76-R113 HydrophobicContact CZ3-CG 4.22Å; W76-R113 WeakPolarHBondContact O-CD 3.07Å; W76-R113 PolarHBondContact O-NH1 3.23Å; W76-L114 HydrophobicContact CH2-CD1 4.48Å; W76-L114 HydrophobicContact CH2-CD2 3.59Å; W76-L114 HydrophobicContact CH2-CG 3.71Å; W76-L114 HydrophobicContact CZ3-CD1 4.26Å; W76-L114 HydrophobicContact CZ3-CD2 4.18Å; W76-L114 HydrophobicContact CZ3-CG 3.84Å
77G98.3Very high98.3Very high0 Ų011.3 Ų11.30%05%0.053CC..SBendtrans-68.5-157178.300000114.4K71 L75 M109 D110K71-G77 WeakPolarHBondContact CB-O 3.29Å; K71-G77 WeakPolarHBondContact CE-O 3.5Å; L75-G77 VanDerWaalsContact CD1-N 3.31Å; L75-G77 WeakPolarHBondContact CD1-O 3.41Å; G77-M109 CarbonylContact C-O 3.58Å; G77-M109 VanDerWaalsContact CA-O 3.22Å; G77-M109 WeakPolarHBondContact CA-O 3.33Å; G77-D110 PolarHBondContact N-OD1 3.33Å
78A98.4Very high98.3Very high0 Ų011.3 Ų11.30%05%0.053CC..  trans-146.2153.1179.500000112.7L69 K71 M109 V112L69-A78 HydrophobicContact CB-CB 3.91Å; L69-A78 HydrophobicContact CD1-CB 4.14Å; L69-A78 HydrophobicContact CD2-CB 3.93Å; L69-A78 HydrophobicContact CG-CB 4.21Å; K71-A78 HydrophobicContact CB-CB 4.13Å; A78-M109 PolarHBondContact N-O 2.84Å; A78-M109 WeakPolarHBondContact O-CA 3.26Å; A78-M109 VanDerWaalsContact O-CB 3.26Å; A78-M109 WeakPolarHBondContact O-CB 3.15Å; A78-V112 HydrophobicContact CB-CG1 4.19Å; A78-V112 VanDerWaalsContact O-CB 3.32Å; A78-V112 WeakPolarHBondContact O-CB 3.44Å
79E98.2Very high98.3Very high3 Ų311.3 Ų11.31%0.0145%0.053CC..SBendtrans-80.2-32.6170.4-73.9-74.4152.200110K25 S27 R29 S70 P72 N91 M109K25-E79 WeakPolarHBondContact CD-O 3.44Å; K25-E79 PolarHBondContact NZ-O 2.74Å; K25-E79 IonicContact NZ-OE2 3.78Å; K25-E79 PolarHBondContact NZ-OE2 3.43Å; S27-E79 WeakPolarHBondContact OG-CG 3.41Å; R29-E79 IonicContact NH1-OE1 2.64Å; S70-E79 PolarHBondContact O-N 3.31Å; P72-E79 HydrophobicContact CG-CG 3.92Å; E79-N91 PolarHBondContact O-N 3.06Å; E79-N91 PolarHBondContact O-OD1 3.44Å; E79-N91 PolarHBondContact OE2-OD1 2.9Å; E79-M109 HydrophobicContact CG-CG 4.41Å; E79-M109 VanDerWaalsContact OE1-CG 3.25Å; E79-M109 WeakPolarHBondContact OE1-CG 3.32Å
80M98.8Very high98.2Very high0 Ų011.3 Ų11.30%05%0.053CC..EExtended strand (participates in β ladder)trans-159.8162.4177.346.9-160.2165.300111.6K25 L69 S70 I89 G279 M281K25-M80 HydrophobicContact CB-CB 4.47Å; K25-M80 HydrophobicContact CB-SD 3.52Å; K25-M80 VanDerWaalsContact CB-SD 3.52Å; K25-M80 HydrophobicContact CD-CB 3.72Å; K25-M80 HydrophobicContact CD-CG 4.04Å; K25-M80 HydrophobicContact CD-SD 3.6Å; K25-M80 HydrophobicContact CG-SD 3.53Å; K25-M80 VanDerWaalsContact CG-SD 3.53Å; L69-M80 WeakPolarHBondContact CA-O 3.27Å; S70-M80 PolarHBondContact N-O 2.86Å; S70-M80 PolarHBondContact O-N 3.17Å; S70-M80 WeakPolarHBondContact OG-CE 2.94Å; M80-I89 CarbonylContact C-O 3.59Å; M80-I89 WeakPolarHBondContact CA-O 3.45Å; M80-I89 WeakPolarHBondContact CB-O 3.35Å; M80-G279 WeakPolarHBondContact CE-O 3.3Å; M80-M281 HydrophobicContact CB-SD 3.85Å; M80-M281 HydrophobicContact CE-CB 4.15Å; M80-M281 HydrophobicContact CG-CB 4.05Å; M80-M281 HydrophobicContact CG-SD 4.01Å; M80-M281 HydrophobicContact SD-CB 3.34Å; M80-M281 WeakPolarHBondContact SD-CB 3.16Å; M80-M281 HydrophobicContact SD-CG 4.48Å; M80-M281 HydrophobicContact SD-SD 4.43Å
81G98.8Very high98.2Very high0 Ų011.4 Ų11.40%05%0.053CC..EExtended strand (participates in β ladder)trans179.4-178.1170.500000112.7V68 C88 I89V68-G81 CarbonylContact O-C 3.55Å; V68-G81 WeakPolarHBondContact O-CA 3.34Å; G81-C88 WeakPolarHBondContact O-CA 3.36Å; G81-I89 PolarHBondContact N-O 3.39Å; G81-I89 PolarHBondContact O-N 3.11Å
82A98.9Very high98Very high0 Ų010.8 Ų10.80%05%0.051CC..EExtended strand (participates in β ladder)trans-133.3161.4171.800000110.4V67 V68 V87 M281 H295 F313V67-A82 WeakPolarHBondContact CA-O 3.43Å; V68-A82 HydrophobicContact CG1-CB 4.29Å; V68-A82 PolarHBondContact N-O 2.94Å; V68-A82 PolarHBondContact O-N 3.49Å; A82-V87 CarbonylContact C-O 3.58Å; A82-V87 WeakPolarHBondContact CA-O 3.36Å; A82-M281 HydrophobicContact CB-CE 3.92Å; A82-H295 WeakPolarHBondContact CB-CE1 3.23Å; A82-H295 VanDerWaalsContact CB-ND1 3.32Å; A82-H295 WeakPolarHBondContact CB-ND1 3.47Å; A82-F313 HydrophobicContact CB-CE2 4.29Å; A82-F313 WeakPolarHBondContact O-CZ 3.19Å
83N98.9Very high97.8Very high0 Ų011.1 Ų11.10%05%0.053CC..EExtended strand (participates in β ladder)trans-118.7171.8173767.5000112.8A66 V67 H85 Q86 V87 L116 A119 F313A66-N83 CarbonylContact O-C 3.54Å; A66-N83 WeakPolarHBondContact O-CA 3.5Å; A66-N83 WeakPolarHBondContact O-CB 3.43Å; V67-N83 HydrophobicContact CG1-CB 3.85Å; N83-H85 PolarHBondContact O-N 3.19Å; N83-H85 VanDerWaalsContact O-N 3.09Å; N83-H85 WeakPolarHBondContact OD1-CA 3.48Å; N83-H85 WeakPolarHBondContact OD1-CB 3.17Å; N83-H85 PolarHBondContact OD1-N 3.37Å; N83-Q86 WeakPolarHBondContact O-CA 3.47Å; N83-Q86 PolarHBondContact O-N 2.92Å; N83-Q86 PolarHBondContact O-NE2 2.9Å; N83-Q86 PolarHBondContact OD1-N 2.94Å; N83-V87 PolarHBondContact N-O 3Å; N83-V87 WeakPolarHBondContact OD1-CB 3.48Å; N83-V87 PolarHBondContact OD1-N 2.89Å; N83-L116 HydrophobicContact CB-CB 4.46Å; N83-L116 HydrophobicContact CB-CD2 4.36Å; N83-L116 WeakPolarHBondContact CB-O 3.37Å; N83-L116 PolarHBondContact ND2-O 3.22Å; N83-A119 PolarHBondContact ND2-O 2.76Å; N83-F313 WeakPolarHBondContact O-CE2 3.49Å
84E98.4Very high97.5Very high76 Ų7610.6 Ų10.636%0.3555%0.049SC..THydrogen-bonded Turntrans-60.2-21.3-179.567.7-171.9128.600113.9A42 Y65 A66 Q86 F313A42-E84 WeakPolarHBondContact CB-OE1 3.49Å; Y65-E84 WeakPolarHBondContact CA-OE1 3.2Å; A66-E84 HydrophobicContact CB-CB 4.22Å; A66-E84 HydrophobicContact CB-CG 4.39Å; A66-E84 PolarHBondContact N-OE1 2.94Å; A66-E84 PolarHBondContact O-N 3.02Å; E84-Q86 PolarHBondContact O-N 2.86Å; E84-Q86 PolarHBondContact O-NE2 3.09Å; E84-F313 HydrophobicContact CB-CB 4.47Å; E84-F313 HydrophobicContact CB-CD1 3.93Å; E84-F313 HydrophobicContact CB-CE1 4.35Å; E84-F313 HydrophobicContact CB-CG 4.15Å
85H98.6Very high97.3Very high72 Ų7212.7 Ų12.733%0.3336%0.057SC..THydrogen-bonded Turntrans-83.42.6173.7-64.1-69.2000114.1Y65 N83 V87 D120Y65-H85 AromaticContact CD1-CD2 3.55Å; Y65-H85 AromaticContact CD1-NE2 3.16Å; Y65-H85 WeakPolarHBondContact CD1-NE2 3.27Å; Y65-H85 AromaticContact CD2-CD2 3.74Å; Y65-H85 AromaticContact CE1-CD2 3.78Å; Y65-H85 AromaticContact CE1-NE2 3.16Å; Y65-H85 WeakPolarHBondContact CE1-NE2 3.35Å; Y65-H85 AromaticContact CE2-CD2 3.95Å; Y65-H85 AromaticContact CG-CD2 3.53Å; Y65-H85 AromaticContact CG-NE2 3.69Å; Y65-H85 AromaticContact CZ-CD2 3.95Å; Y65-H85 AromaticContact CZ-NE2 3.67Å; N83-H85 PolarHBondContact O-N 3.19Å; N83-H85 VanDerWaalsContact O-N 3.09Å; N83-H85 WeakPolarHBondContact OD1-CA 3.48Å; N83-H85 WeakPolarHBondContact OD1-CB 3.17Å; N83-H85 PolarHBondContact OD1-N 3.37Å; H85-V87 VanDerWaalsContact C-N 3.26Å; H85-V87 HydrophobicContact CB-CG2 4.48Å; H85-V87 PolarHBondContact O-N 2.9Å; H85-D120 HydrophobicContact CB-CB 4.02Å
86Q98.6Very high97Very high7 Ų712.6 Ų12.63%0.0336%0.057CC..  trans65.427.3-178.4-42.5-55.4-79.900113.7N83 E84 R160 V285 H295N83-Q86 WeakPolarHBondContact O-CA 3.47Å; N83-Q86 PolarHBondContact O-N 2.92Å; N83-Q86 PolarHBondContact O-NE2 2.9Å; N83-Q86 PolarHBondContact OD1-N 2.94Å; E84-Q86 PolarHBondContact O-N 2.86Å; E84-Q86 PolarHBondContact O-NE2 3.09Å; Q86-R160 HydrophobicContact CB-CG 4.27Å; Q86-R160 VanDerWaalsContact CG-CZ 3.46Å; Q86-V285 HydrophobicContact CB-CG1 3.68Å; Q86-V285 HydrophobicContact CB-CG2 4.14Å; Q86-V285 HydrophobicContact CG-CG1 4.33Å; Q86-H295 PolarHBondContact OE1-NE2 2.95Å
87V98.9Very high96.7Very high0 Ų014.1 Ų14.10%06%0.063CC..  trans-77.4128.4163.6-176.80000107.5A82 N83 H85 I89 L116 A125 I157 S158 D159A82-V87 CarbonylContact C-O 3.58Å; A82-V87 WeakPolarHBondContact CA-O 3.36Å; N83-V87 PolarHBondContact N-O 3Å; N83-V87 WeakPolarHBondContact OD1-CB 3.48Å; N83-V87 PolarHBondContact OD1-N 2.89Å; H85-V87 VanDerWaalsContact C-N 3.26Å; H85-V87 HydrophobicContact CB-CG2 4.48Å; H85-V87 PolarHBondContact O-N 2.9Å; V87-I89 HydrophobicContact CG1-CD1 4.45Å; V87-I89 HydrophobicContact CG1-CG1 4.16Å; V87-L116 HydrophobicContact CB-CD2 4.49Å; V87-L116 HydrophobicContact CG1-CD2 4.36Å; V87-L116 VanDerWaalsContact O-CD2 3.26Å; V87-L116 WeakPolarHBondContact O-CD2 3.32Å; V87-A125 HydrophobicContact CG1-CB 4.33Å; V87-I157 HydrophobicContact CG1-CG2 4.22Å; V87-S158 CarbonylContact C-O 3.57Å; V87-S158 VanDerWaalsContact CA-O 3.29Å; V87-S158 WeakPolarHBondContact CA-O 3.48Å; V87-D159 HydrophobicContact CG2-CB 4.35Å
88C98.9Very high96.5Very high0 Ų016.3 Ų16.30%07%0.073CC..EExtended strand (participates in β ladder)trans-112.5136.9172.9-63.30000109.4F23 G81 I157 S158 S283F23-C88 HydrophobicContact CB-CB 4.26Å; F23-C88 HydrophobicContact CD1-CB 4.07Å; F23-C88 HydrophobicContact CD2-CB 4.16Å; F23-C88 HydrophobicContact CE1-CB 4.48Å; F23-C88 HydrophobicContact CG-CB 3.9Å; G81-C88 WeakPolarHBondContact O-CA 3.36Å; C88-I157 CarbonylContact O-C 3.58Å; C88-I157 WeakPolarHBondContact O-CA 3.44Å; C88-S158 PolarHBondContact N-O 3.18Å; C88-S158 PolarHBondContact O-N 2.78Å; C88-S283 VanDerWaalsContact SG-CB 3.6Å
89I98.9Very high96.1Very high0 Ų019.5 Ų19.50%010%0.095CC..EExtended strand (participates in β ladder)trans-133.1137.9176.5-55.3-173.9000109.3M80 G81 V87 V112 L116 A125 I129 F155 L156 I157M80-I89 CarbonylContact C-O 3.59Å; M80-I89 WeakPolarHBondContact CA-O 3.45Å; M80-I89 WeakPolarHBondContact CB-O 3.35Å; G81-I89 PolarHBondContact N-O 3.39Å; G81-I89 PolarHBondContact O-N 3.11Å; V87-I89 HydrophobicContact CG1-CD1 4.45Å; V87-I89 HydrophobicContact CG1-CG1 4.16Å; I89-V112 HydrophobicContact CB-CG1 4.12Å; I89-V112 HydrophobicContact CG2-CB 4.26Å; I89-V112 HydrophobicContact CG2-CG1 3.92Å; I89-V112 HydrophobicContact CG2-CG2 4.02Å; I89-L116 HydrophobicContact CB-CD1 4.48Å; I89-L116 HydrophobicContact CB-CD2 4.17Å; I89-L116 HydrophobicContact CB-CG 4.17Å; I89-L116 HydrophobicContact CD1-CD2 4.05Å; I89-L116 HydrophobicContact CD1-CG 3.94Å; I89-L116 HydrophobicContact CG1-CD2 3.72Å; I89-L116 HydrophobicContact CG1-CG 3.98Å; I89-A125 HydrophobicContact CD1-CB 3.88Å; I89-I129 HydrophobicContact CD1-CD1 4.42Å; I89-F155 HydrophobicContact CG2-CD1 4.39Å; I89-L156 WeakPolarHBondContact CA-O 3.31Å; I89-I157 HydrophobicContact CD1-CG1 4.35Å; I89-I157 HydrophobicContact CD1-CG2 4.34Å; I89-I157 HydrophobicContact CG1-CB 4.44Å; I89-I157 HydrophobicContact CG1-CG1 4.12Å; I89-I157 HydrophobicContact CG1-CG2 4.03Å; I89-I157 HydrophobicContact CG2-CG1 4.11Å
90G98.6Very high95.7Very high0 Ų020 Ų200%010%0.1CC..EExtended strand (participates in β ladder)trans-137.4150.716500000110.1F155 L156G90-F155 CarbonylContact O-C 3.57Å; G90-F155 WeakPolarHBondContact O-CA 3.4Å; G90-L156 PolarHBondContact N-O 2.7Å; G90-L156 PolarHBondContact O-N 2.8Å
91N96.8Very high95.2Very high1 Ų124.9 Ų24.91%0.00513%0.126CC..EExtended strand (participates in β ladder)trans-121.3158.517972.5-38.5000113.3K25 E79 V112 N153 S154 F155K25-N91 VanDerWaalsContact CE-O 3.26Å; K25-N91 WeakPolarHBondContact CE-O 3.36Å; K25-N91 PolarHBondContact NZ-O 3.48Å; K25-N91 PolarHBondContact NZ-OD1 2.88Å; E79-N91 PolarHBondContact O-N 3.06Å; E79-N91 PolarHBondContact O-OD1 3.44Å; E79-N91 PolarHBondContact OE2-OD1 2.9Å; N91-V112 HydrophobicContact CB-CG2 3.72Å; N91-N153 PolarHBondContact ND2-ND2 2.95Å; N91-S154 CarbonylContact C-O 3.46Å; N91-S154 WeakPolarHBondContact CA-O 3.46Å; N91-F155 HydrophobicContact CB-CD1 3.61Å; N91-F155 HydrophobicContact CB-CE1 3.77Å; N91-F155 HydrophobicContact CB-CG 4.45Å
92E93.5Very high94.3Very high1 Ų127.6 Ų27.61%0.00515%0.154CC..EExtended strand (participates in β ladder)trans-128.3150.8170.6-59.6-55.6159.400110.8C6 D7 T8 N153 S154 I185C6-E92 WeakPolarHBondContact CA-OE2 2.9Å; C6-E92 WeakPolarHBondContact CB-OE2 3.4Å; C6-E92 PolarHBondContact N-OE2 2.98Å; C6-E92 PolarHBondContact SG-OE2 3.21Å; D7-E92 WeakPolarHBondContact CA-OE1 3.36Å; D7-E92 PolarHBondContact N-OE1 2.87Å; T8-E92 PolarHBondContact N-OE1 2.71Å; T8-E92 PolarHBondContact OG1-OE1 3.06Å; E92-N153 VanDerWaalsContact O-CA 3.29Å; E92-N153 WeakPolarHBondContact O-CA 3.16Å; E92-N153 PolarHBondContact O-ND2 3.34Å; E92-S154 PolarHBondContact N-O 2.9Å; E92-S154 PolarHBondContact O-N 3.19Å; E92-I185 HydrophobicContact CB-CD1 4.45Å; E92-I185 HydrophobicContact CG-CD1 3.79Å; E92-I185 HydrophobicContact CG-CG1 3.89Å
93A93.4Very high94Very high8 Ų835.8 Ų35.87%0.06619%0.192CC..EExtended strand (participates in β ladder)trans-77.1128.5170.600000110.3W95 Y151 N187A93-W95 HydrophobicContact CB-CH2 3.68Å; A93-W95 HydrophobicContact CB-CZ2 4.07Å; A93-W95 HydrophobicContact CB-CZ3 4.17Å; A93-Y151 HydrophobicContact CB-CD1 3.46Å; A93-Y151 VanDerWaalsContact CB-CD1 3.46Å; A93-Y151 HydrophobicContact CB-CD2 3.61Å; A93-Y151 HydrophobicContact CB-CE1 3.7Å; A93-Y151 HydrophobicContact CB-CE2 3.87Å; A93-Y151 HydrophobicContact CB-CG 3.38Å; A93-N187 WeakPolarHBondContact CB-ND2 3.28Å; A93-N187 PolarHBondContact N-ND2 2.96Å; A93-N187 VanDerWaalsContact O-CA 3.22Å; A93-N187 WeakPolarHBondContact O-CA 3.49Å; A93-N187 WeakPolarHBondContact O-CB 3.2Å; A93-N187 VanDerWaalsContact O-CG 3.26Å; A93-N187 PolarHBondContact O-ND2 3.37Å
94V92.1Very high93.8Very high0 Ų038.4 Ų38.40%021%0.205CC..EExtended strand (participates in β ladder)trans-127.3146.1175.2-64.40000110.9H152 Y189V94-H152 HydrophobicContact CG2-CB 4.07Å; V94-H152 WeakPolarHBondContact CG2-O 3.17Å; V94-H152 PolarHBondContact N-O 2.94Å; V94-H152 PolarHBondContact O-N 3.27Å; V94-H152 VanDerWaalsContact O-N 3.08Å; V94-Y189 HydrophobicContact CB-CD1 4.33Å; V94-Y189 HydrophobicContact CB-CE1 4.04Å; V94-Y189 HydrophobicContact CG2-CD1 4.15Å; V94-Y189 HydrophobicContact CG2-CE1 3.51Å
95W90.9Very high93.8Very high50 Ų5035.3 Ų35.319%0.18919%0.192CC..  trans-122.8135.9176.6-63.5-84.6000109.8A93 F149 T150 Y151 N187 R231A93-W95 HydrophobicContact CB-CH2 3.68Å; A93-W95 HydrophobicContact CB-CZ2 4.07Å; A93-W95 HydrophobicContact CB-CZ3 4.17Å; W95-F149 HydrophobicContact CH2-CE2 4.4Å; W95-F149 AromaticContact CH2-CZ 3.99Å; W95-F149 HydrophobicContact CH2-CZ 3.99Å; W95-F149 AromaticContact CZ2-CE2 3.72Å; W95-F149 HydrophobicContact CZ2-CE2 3.72Å; W95-F149 AromaticContact CZ2-CZ 3.6Å; W95-F149 HydrophobicContact CZ2-CZ 3.6Å; W95-T150 PolarHBondContact NE1-O 2.9Å; W95-Y151 HydrophobicContact CZ2-CD1 4.08Å; W95-Y151 HydrophobicContact CZ2-CG 4.37Å; W95-N187 HydrophobicContact CZ3-CB 4.27Å; W95-R231 VanDerWaalsContact CE2-NH1 3.29Å
96G90.9Very high93.8Very high4 Ų431.9 Ų31.94%0.04118%0.176CC..  trans-145.7-176.4-177.600000111.9E98 Y224 F226G96-E98 PolarHBondContact O-N 3.46Å; G96-E98 VanDerWaalsContact O-N 3.15Å; G96-Y224 CarbonylContact C-O 3.34Å; G96-Y224 WeakPolarHBondContact CA-O 3.31Å; G96-F226 VanDerWaalsContact C-CZ 3.41Å; G96-F226 WeakPolarHBondContact O-CE2 3.39Å; G96-F226 WeakPolarHBondContact O-CZ 3.3Å
97R92.6Very high93.7Very high74 Ų7431.7 Ų31.728%0.27918%0.175SC..SBendtrans-57.4-30.2-179.1-61.3-176.2-176.6-1603.1113.6W211 V223 Y224 S225 F226R97-W211 HydrophobicContact CB-CD2 4.16Å; R97-W211 HydrophobicContact CB-CE3 4.33Å; R97-W211 HydrophobicContact CB-CH2 3.81Å; R97-W211 HydrophobicContact CB-CZ2 3.6Å; R97-W211 HydrophobicContact CB-CZ3 4.17Å; R97-W211 VanDerWaalsContact NH1-CD1 3.3Å; R97-V223 WeakPolarHBondContact CD-O 3.19Å; R97-V223 PolarHBondContact NE-O 3.03Å; R97-Y224 PolarHBondContact N-O 3.12Å; R97-S225 WeakPolarHBondContact CG-O 3.46Å; R97-S225 PolarHBondContact NE-O 3Å; R97-F226 HydrophobicContact CB-CE1 4.47Å; R97-F226 HydrophobicContact CG-CD1 4.22Å; R97-F226 HydrophobicContact CG-CE1 4.31Å
98E93.1Very high93.7Very high47 Ų4731.7 Ų31.722%0.2218%0.176CC..SBendtrans-77127.7170.8-166.462.1-145.200109.9G96 H152 S169 Y205 W211G96-E98 PolarHBondContact O-N 3.46Å; G96-E98 VanDerWaalsContact O-N 3.15Å; E98-H152 PolarHBondContact O-CE1 3.46Å; E98-S169 WeakPolarHBondContact CB-OG 3.28Å; E98-Y205 VanDerWaalsContact CD-OH 3.28Å; E98-Y205 PolarHBondContact OE1-OH 2.97Å; E98-Y205 VanDerWaalsContact OE2-CE1 3.3Å; E98-Y205 WeakPolarHBondContact OE2-CE1 3.4Å; E98-Y205 PolarHBondContact OE2-OH 3.49Å; E98-W211 HydrophobicContact CB-CH2 4.28Å; E98-W211 WeakPolarHBondContact OE2-CH2 3.35Å
99S91.1Very high93.6Very high66 Ų6631.7 Ų31.746%0.46218%0.176SC..  trans-67.1138.8177.3-169.50000110.7D101 H152S99-D101 VanDerWaalsContact C-N 3.32Å; S99-D101 WeakPolarHBondContact OG-CB 3.29Å; S99-D101 PolarHBondContact OG-N 3.27Å; S99-D101 VanDerWaalsContact OG-N 3.1Å; S99-D101 PolarHBondContact OG-OD2 3.47Å; S99-H152 PolarHBondContact O-CE1 3.11Å; S99-H152 PolarHBondContact O-NE2 3.09Å
100A89.8Confident93.6Very high13 Ų1331.7 Ų31.711%0.10718%0.176CC..  trans-90-3.1169.400000112.3T150 Y151A100-T150 WeakPolarHBondContact O-CB 3.45Å; A100-Y151 VanDerWaalsContact CB-C 3.47Å; A100-Y151 VanDerWaalsContact CB-CA 3.44Å
101D86.6Confident93.6Very high103 Ų10331.7 Ų31.755%0.55118%0.176SC*.  trans-72.6132.1176.1-56-27.8000109.5S99 T150S99-D101 VanDerWaalsContact C-N 3.32Å; S99-D101 WeakPolarHBondContact OG-CB 3.29Å; S99-D101 PolarHBondContact OG-N 3.27Å; S99-D101 VanDerWaalsContact OG-N 3.1Å; S99-D101 PolarHBondContact OG-OD2 3.47Å; D101-T150 PolarHBondContact OD1-OG1 3.34Å
102G81.4Confident93.8Very high57 Ų5731.7 Ų31.759%0.58818%0.176SC*.  trans171.6-174.3-177.100000112.8
103E91.6Very high94Very high172 Ų17232.6 Ų32.680%0.80418%0.179SC*.SBendtrans-64.8156.1177.7-63.7-64.3149.300111.9A105E103-A105 PolarHBondContact O-N 2.82Å
104E95.5Very high94.3Very high55 Ų5532.2 Ų32.226%0.25718%0.176SC..  trans-55.1124.5170.3-74.9-179.8151.600110.6Y55 K337 R339Y55-E104 HydrophobicContact CD1-CG 4.36Å; Y55-E104 WeakPolarHBondContact CD1-OE1 3.45Å; Y55-E104 HydrophobicContact CD2-CG 4.31Å; Y55-E104 HydrophobicContact CG-CB 4.27Å; Y55-E104 HydrophobicContact CG-CG 4Å; E104-K337 WeakPolarHBondContact OE2-CE 3.45Å; E104-K337 IonicContact OE2-NZ 2.79Å; E104-K337 PolarHBondContact OE2-NZ 3.3Å; E104-R339 IonicContact OE1-CZ 2.64Å; E104-R339 IonicContact OE1-NE 2.66Å; E104-R339 PolarHBondContact OE1-NE 3.01Å; E104-R339 IonicContact OE1-NH2 3.93Å; E104-R339 IonicContact OE2-NH2 2.71Å
105A97.3Very high94.6Very high12 Ų1232.2 Ų32.210%0.09918%0.176CC..  trans-139.4-157.4174.800000109.3E103 Y136 G139E103-A105 PolarHBondContact O-N 2.82Å; A105-Y136 WeakPolarHBondContact CB-O 3.39Å; A105-G139 CarbonylContact C-O 3.5Å; A105-G139 PolarHBondContact N-O 2.86Å
106L98.3Very high95Very high0 Ų029.8 Ų29.80%017%0.167CC..BIsolated β-bridgetrans-66.6136169.8-65.5176.7000109.7C53 I56 I58 D110 L111 L114 L132 Y136 Q138 G139C53-L106 HydrophobicContact CB-CD2 3.98Å; I56-L106 HydrophobicContact CD1-CD2 3.97Å; I56-L106 HydrophobicContact CD1-CG 3.97Å; I56-L106 HydrophobicContact CG1-CD2 3.91Å; I56-L106 HydrophobicContact CG1-CG 4.41Å; I58-L106 HydrophobicContact CD1-CD2 4.48Å; I58-L106 HydrophobicContact CG2-CD2 3.97Å; L106-D110 HydrophobicContact CB-CB 4.44Å; L106-D110 HydrophobicContact CD2-CB 4.2Å; L106-L111 HydrophobicContact CB-CD2 4.36Å; L106-L111 HydrophobicContact CB-CG 4.36Å; L106-L111 HydrophobicContact CD1-CD2 3.74Å; L106-L114 HydrophobicContact CD1-CD1 4.12Å; L106-L114 HydrophobicContact CD2-CD1 4.13Å; L106-L132 HydrophobicContact CD1-CB 4.05Å; L106-L132 HydrophobicContact CD1-CD2 4.38Å; L106-Y136 HydrophobicContact CD1-CD2 4.23Å; L106-Y136 HydrophobicContact CD1-CG 4.36Å; L106-Q138 CarbonylContact O-C 3.31Å; L106-Q138 WeakPolarHBondContact O-CA 3.16Å; L106-G139 PolarHBondContact O-N 2.95Å; L106-G139 VanDerWaalsContact O-N 3.1Å
107L97.9Very high95.3Very high2 Ų229.9 Ų29.91%0.0117%0.166CC..  trans-77.7157.1166.2-68.6-178.5000110.5T54 Y55 W74 M109 D110 L111T54-L107 HydrophobicContact CG2-CD1 3.69Å; Y55-L107 HydrophobicContact CD2-CD1 4.15Å; Y55-L107 HydrophobicContact CD2-CD2 4.15Å; Y55-L107 HydrophobicContact CD2-CG 3.95Å; Y55-L107 HydrophobicContact CE2-CD1 3.62Å; Y55-L107 HydrophobicContact CE2-CD2 3.79Å; Y55-L107 HydrophobicContact CE2-CG 3.79Å; W74-L107 HydrophobicContact CH2-CD1 4.17Å; L107-M109 HydrophobicContact CB-CE 3.68Å; L107-M109 HydrophobicContact CB-SD 4.5Å; L107-M109 HydrophobicContact CD1-CE 3.52Å; L107-M109 HydrophobicContact CD2-CE 4.33Å; L107-M109 HydrophobicContact CG-CE 4.05Å; L107-M109 PolarHBondContact O-N 2.78Å; L107-D110 HydrophobicContact CB-CB 4.48Å; L107-D110 PolarHBondContact N-OD2 2.93Å; L107-D110 WeakPolarHBondContact O-CA 3.41Å; L107-D110 WeakPolarHBondContact O-CB 3.4Å; L107-D110 PolarHBondContact O-N 2.97Å; L107-L111 PolarHBondContact O-N 2.7Å
108G97.7Very high95.6Very high1 Ų128.2 Ų28.21%0.0116%0.16CC..Hα-helixtrans-52-38.7167.700000112.7D110 L111 V112 N153 F155G108-D110 VanDerWaalsContact C-N 3.31Å; G108-D110 PolarHBondContact O-N 3.36Å; G108-L111 WeakPolarHBondContact O-CA 3.31Å; G108-L111 WeakPolarHBondContact O-CB 3.23Å; G108-L111 PolarHBondContact O-N 3.28Å; G108-L111 VanDerWaalsContact O-N 3.12Å; G108-V112 WeakPolarHBondContact O-CG2 3.41Å; G108-V112 PolarHBondContact O-N 3.01Å; G108-N153 WeakPolarHBondContact CA-OD1 3.22Å; G108-F155 WeakPolarHBondContact O-CE1 3.35Å
109M98.4Very high95.9Very high0 Ų026 Ų260%015%0.149CC..Hα-helixtrans-67.1-33.3177.6-59.671.470.300111.8L75 G77 A78 E79 L107 L111 V112 R113 C142 Y151L75-M109 HydrophobicContact CD1-CB 4.09Å; L75-M109 HydrophobicContact CD2-CB 4.19Å; L75-M109 HydrophobicContact CD2-CE 3.93Å; L75-M109 HydrophobicContact CD2-CG 4.16Å; G77-M109 CarbonylContact C-O 3.58Å; G77-M109 VanDerWaalsContact CA-O 3.22Å; G77-M109 WeakPolarHBondContact CA-O 3.33Å; A78-M109 PolarHBondContact N-O 2.84Å; A78-M109 WeakPolarHBondContact O-CA 3.26Å; A78-M109 VanDerWaalsContact O-CB 3.26Å; A78-M109 WeakPolarHBondContact O-CB 3.15Å; E79-M109 HydrophobicContact CG-CG 4.41Å; E79-M109 VanDerWaalsContact OE1-CG 3.25Å; E79-M109 WeakPolarHBondContact OE1-CG 3.32Å; L107-M109 HydrophobicContact CB-CE 3.68Å; L107-M109 HydrophobicContact CB-SD 4.5Å; L107-M109 HydrophobicContact CD1-CE 3.52Å; L107-M109 HydrophobicContact CD2-CE 4.33Å; L107-M109 HydrophobicContact CG-CE 4.05Å; L107-M109 PolarHBondContact O-N 2.78Å; M109-L111 VanDerWaalsContact C-N 3.33Å; M109-V112 PolarHBondContact O-N 3.01Å; M109-R113 PolarHBondContact O-N 3.5Å; M109-C142 HydrophobicContact CE-CB 4.08Å; M109-Y151 HydrophobicContact SD-CE2 4.17Å; M109-Y151 PolarHBondContact SD-OH 2.98Å
110D98.9Very high96.3Very high0 Ų025.1 Ų25.10%014%0.139CC..Hα-helixtrans-66-41172.1-63.1-23.5000110.1C53 T54 W76 G77 L106 L107 G108 V112 R113 L114C53-D110 HydrophobicContact CB-CB 4.36Å; T54-D110 WeakPolarHBondContact CB-OD1 2.95Å; T54-D110 WeakPolarHBondContact CB-OD2 3.47Å; T54-D110 PolarHBondContact N-OD1 2.96Å; T54-D110 PolarHBondContact N-OD2 3.3Å; T54-D110 PolarHBondContact OG1-OD1 3.42Å; T54-D110 PolarHBondContact OG1-OD2 3.34Å; W76-D110 HydrophobicContact CE3-CB 4.1Å; W76-D110 HydrophobicContact CZ3-CB 4.03Å; G77-D110 PolarHBondContact N-OD1 3.33Å; L106-D110 HydrophobicContact CB-CB 4.44Å; L106-D110 HydrophobicContact CD2-CB 4.2Å; L107-D110 HydrophobicContact CB-CB 4.48Å; L107-D110 PolarHBondContact N-OD2 2.93Å; L107-D110 WeakPolarHBondContact O-CA 3.41Å; L107-D110 WeakPolarHBondContact O-CB 3.4Å; L107-D110 PolarHBondContact O-N 2.97Å; G108-D110 VanDerWaalsContact C-N 3.31Å; G108-D110 PolarHBondContact O-N 3.36Å; D110-V112 PolarHBondContact O-N 3.08Å; D110-R113 PolarHBondContact O-N 2.73Å; D110-L114 WeakPolarHBondContact O-CB 3.34Å; D110-L114 WeakPolarHBondContact O-CD1 3.49Å; D110-L114 VanDerWaalsContact O-CG 3.23Å; D110-L114 WeakPolarHBondContact O-CG 3.24Å; D110-L114 PolarHBondContact O-N 3.11Å
111L98.8Very high96.7Very high0 Ų026.3 Ų26.30%015%0.146CC..Hα-helixtrans-63.7-36.1176.5-64.6170.5000112.6L106 L107 G108 M109 G115 I129 L132 F155L106-L111 HydrophobicContact CB-CD2 4.36Å; L106-L111 HydrophobicContact CB-CG 4.36Å; L106-L111 HydrophobicContact CD1-CD2 3.74Å; L107-L111 PolarHBondContact O-N 2.7Å; G108-L111 WeakPolarHBondContact O-CA 3.31Å; G108-L111 WeakPolarHBondContact O-CB 3.23Å; G108-L111 PolarHBondContact O-N 3.28Å; G108-L111 VanDerWaalsContact O-N 3.12Å; M109-L111 VanDerWaalsContact C-N 3.33Å; L111-G115 PolarHBondContact O-N 3.02Å; L111-I129 HydrophobicContact CB-CG1 4.4Å; L111-I129 HydrophobicContact CB-CG2 4.17Å; L111-I129 HydrophobicContact CD1-CG2 4.19Å; L111-I129 HydrophobicContact CD2-CG2 4.39Å; L111-I129 HydrophobicContact CG-CG2 4.49Å; L111-L132 HydrophobicContact CD2-CB 3.63Å; L111-L132 HydrophobicContact CD2-CD1 4.15Å; L111-F155 HydrophobicContact CB-CE1 4.18Å; L111-F155 HydrophobicContact CB-CZ 3.99Å; L111-F155 HydrophobicContact CD1-CZ 4.09Å
112V98.9Very high97.3Very high0 Ų021.4 Ų21.40%012%0.12CC..Hα-helixtrans-56.5-54.2172171.30000110.5A78 I89 N91 G108 M109 D110 G115 L116 F155A78-V112 HydrophobicContact CB-CG1 4.19Å; A78-V112 VanDerWaalsContact O-CB 3.32Å; A78-V112 WeakPolarHBondContact O-CB 3.44Å; I89-V112 HydrophobicContact CB-CG1 4.12Å; I89-V112 HydrophobicContact CG2-CB 4.26Å; I89-V112 HydrophobicContact CG2-CG1 3.92Å; I89-V112 HydrophobicContact CG2-CG2 4.02Å; N91-V112 HydrophobicContact CB-CG2 3.72Å; G108-V112 WeakPolarHBondContact O-CG2 3.41Å; G108-V112 PolarHBondContact O-N 3.01Å; M109-V112 PolarHBondContact O-N 3.01Å; D110-V112 PolarHBondContact O-N 3.08Å; V112-G115 PolarHBondContact O-N 3.19Å; V112-L116 HydrophobicContact CG1-CD1 4.14Å; V112-L116 WeakPolarHBondContact O-CG 3.41Å; V112-L116 PolarHBondContact O-N 3.06Å; V112-L116 VanDerWaalsContact O-N 3.07Å; V112-F155 HydrophobicContact CG2-CD1 3.98Å; V112-F155 HydrophobicContact CG2-CE1 3.83Å
113R98.9Very high98.1Very high20 Ų2022.4 Ų22.48%0.07511%0.109CC..Hα-helixtrans-63.9-46.3-178.5177.5175.3176.5162.38.1111.6L69 W76 M109 D110 G115 L116 E117L69-R113 HydrophobicContact CD1-CB 4.38Å; L69-R113 HydrophobicContact CD1-CG 3.84Å; W76-R113 HydrophobicContact CH2-CB 4.37Å; W76-R113 HydrophobicContact CH2-CG 3.92Å; W76-R113 HydrophobicContact CZ2-CG 4.3Å; W76-R113 HydrophobicContact CZ3-CB 4.21Å; W76-R113 HydrophobicContact CZ3-CG 4.22Å; W76-R113 WeakPolarHBondContact O-CD 3.07Å; W76-R113 PolarHBondContact O-NH1 3.23Å; M109-R113 PolarHBondContact O-N 3.5Å; D110-R113 PolarHBondContact O-N 2.73Å; R113-G115 VanDerWaalsContact C-N 3.3Å; R113-G115 PolarHBondContact O-N 3.43Å; R113-L116 PolarHBondContact O-N 3.16Å; R113-E117 HydrophobicContact CG-CG 4.26Å; R113-E117 IonicContact CZ-OE1 3.02Å; R113-E117 VanDerWaalsContact CZ-OE1 3.31Å; R113-E117 IonicContact NE-OE1 2.75Å; R113-E117 PolarHBondContact NE-OE1 3.11Å; R113-E117 IonicContact NE-OE2 3.35Å; R113-E117 IonicContact NH2-OE1 3.03Å; R113-E117 PolarHBondContact NH2-OE1 3.17Å; R113-E117 WeakPolarHBondContact O-CB 3.14Å; R113-E117 WeakPolarHBondContact O-CG 3.39Å; R113-E117 PolarHBondContact O-N 3.23Å
114L98.9Very high98.5Very high0 Ų018.7 Ų18.70%09%0.09CC..Hα-helixtrans-62.9-37.7179.2-70.7165.4000111.9I58 W76 L106 D110 R118 L132I58-L114 HydrophobicContact CD1-CD1 3.66Å; I58-L114 HydrophobicContact CD1-CD2 3.87Å; I58-L114 HydrophobicContact CD1-CG 4.45Å; W76-L114 HydrophobicContact CH2-CD1 4.48Å; W76-L114 HydrophobicContact CH2-CD2 3.59Å; W76-L114 HydrophobicContact CH2-CG 3.71Å; W76-L114 HydrophobicContact CZ3-CD1 4.26Å; W76-L114 HydrophobicContact CZ3-CD2 4.18Å; W76-L114 HydrophobicContact CZ3-CG 3.84Å; L106-L114 HydrophobicContact CD1-CD1 4.12Å; L106-L114 HydrophobicContact CD2-CD1 4.13Å; D110-L114 WeakPolarHBondContact O-CB 3.34Å; D110-L114 WeakPolarHBondContact O-CD1 3.49Å; D110-L114 VanDerWaalsContact O-CG 3.23Å; D110-L114 WeakPolarHBondContact O-CG 3.24Å; D110-L114 PolarHBondContact O-N 3.11Å; L114-R118 WeakPolarHBondContact O-CB 3.16Å; L114-R118 WeakPolarHBondContact O-CG 3.16Å; L114-R118 PolarHBondContact O-N 3.49Å; L114-R118 VanDerWaalsContact O-N 3.15Å; L114-L132 HydrophobicContact CB-CD1 3.59Å; L114-L132 HydrophobicContact CD1-CD1 3.85Å; L114-L132 HydrophobicContact CG-CD1 4.26Å
115G98.9Very high98.6Very high0 Ų016.1 Ų16.10%08%0.078CC..Hα-helixtrans-60.5-48.7173.100000111.8L111 V112 R113 R118 A119L111-G115 PolarHBondContact O-N 3.02Å; V112-G115 PolarHBondContact O-N 3.19Å; R113-G115 VanDerWaalsContact C-N 3.3Å; R113-G115 PolarHBondContact O-N 3.43Å; G115-R118 PolarHBondContact O-N 3.13Å; G115-A119 VanDerWaalsContact O-CB 3.3Å; G115-A119 WeakPolarHBondContact O-CB 3.24Å; G115-A119 PolarHBondContact O-N 2.98Å; G115-A119 VanDerWaalsContact O-N 3.09Å
116L98.9Very high98.7Very high0 Ų015.5 Ų15.50%07%0.073CC..Hα-helixtrans-64.1-42.8178.2-71.3169.9000112.9V67 L69 N83 V87 I89 V112 R113 R118V67-L116 HydrophobicContact CG1-CB 3.74Å; L69-L116 HydrophobicContact CD2-CD1 3.58Å; N83-L116 HydrophobicContact CB-CB 4.46Å; N83-L116 HydrophobicContact CB-CD2 4.36Å; N83-L116 WeakPolarHBondContact CB-O 3.37Å; N83-L116 PolarHBondContact ND2-O 3.22Å; V87-L116 HydrophobicContact CB-CD2 4.49Å; V87-L116 HydrophobicContact CG1-CD2 4.36Å; V87-L116 VanDerWaalsContact O-CD2 3.26Å; V87-L116 WeakPolarHBondContact O-CD2 3.32Å; I89-L116 HydrophobicContact CB-CD1 4.48Å; I89-L116 HydrophobicContact CB-CD2 4.17Å; I89-L116 HydrophobicContact CB-CG 4.17Å; I89-L116 HydrophobicContact CD1-CD2 4.05Å; I89-L116 HydrophobicContact CD1-CG 3.94Å; I89-L116 HydrophobicContact CG1-CD2 3.72Å; I89-L116 HydrophobicContact CG1-CG 3.98Å; V112-L116 HydrophobicContact CG1-CD1 4.14Å; V112-L116 WeakPolarHBondContact O-CG 3.41Å; V112-L116 PolarHBondContact O-N 3.06Å; V112-L116 VanDerWaalsContact O-N 3.07Å; R113-L116 PolarHBondContact O-N 3.16Å; L116-R118 VanDerWaalsContact C-N 3.26Å; L116-R118 PolarHBondContact O-N 3.17Å
117E98.9Very high98.7Very high5 Ų518.9 Ų18.92%0.0239%0.091CC..Hα-helixtrans-70.2-21.6-179.2-77.1-179.1168.200112.6T64 Y65 V67 R113T64-E117 CarbonylContact C-O 3.51Å; T64-E117 WeakPolarHBondContact CA-O 3.4Å; T64-E117 HydrophobicContact CG2-CB 4.04Å; Y65-E117 PolarHBondContact N-O 3.09Å; V67-E117 HydrophobicContact CG1-CG 3.89Å; V67-E117 HydrophobicContact CG2-CG 4.11Å; R113-E117 HydrophobicContact CG-CG 4.26Å; R113-E117 IonicContact CZ-OE1 3.02Å; R113-E117 VanDerWaalsContact CZ-OE1 3.31Å; R113-E117 IonicContact NE-OE1 2.75Å; R113-E117 PolarHBondContact NE-OE1 3.11Å; R113-E117 IonicContact NE-OE2 3.35Å; R113-E117 IonicContact NH2-OE1 3.03Å; R113-E117 PolarHBondContact NH2-OE1 3.17Å; R113-E117 WeakPolarHBondContact O-CB 3.14Å; R113-E117 WeakPolarHBondContact O-CG 3.39Å; R113-E117 PolarHBondContact O-N 3.23Å
118R98.8Very high98.8Very high39 Ų3920.2 Ų20.215%0.14710%0.099CC..Hα-helixtrans-119.7-1.8-168.3-56.4177.6175.7-163.9-5.9115.1E59 V61 L114 G115 L116 V128E59-R118 PolarHBondContact O-NH2 3.43Å; E59-R118 VanDerWaalsContact O-NH2 3.12Å; V61-R118 HydrophobicContact CG1-CG 4.39Å; V61-R118 HydrophobicContact CG2-CG 3.83Å; L114-R118 WeakPolarHBondContact O-CB 3.16Å; L114-R118 WeakPolarHBondContact O-CG 3.16Å; L114-R118 PolarHBondContact O-N 3.49Å; L114-R118 VanDerWaalsContact O-N 3.15Å; G115-R118 PolarHBondContact O-N 3.13Å; L116-R118 VanDerWaalsContact C-N 3.26Å; L116-R118 PolarHBondContact O-N 3.17Å; R118-V128 HydrophobicContact CB-CG1 4.03Å; R118-V128 HydrophobicContact CB-CG2 4.16Å
119A98.8Very high98.9Very high0 Ų020.1 Ų20.10%010%0.099CC..  trans-129.6137.2-177.900000113.6Y65 N83 G115 K124 A125 V128Y65-A119 VanDerWaalsContact CE2-C 3.48Å; N83-A119 PolarHBondContact ND2-O 2.76Å; G115-A119 VanDerWaalsContact O-CB 3.3Å; G115-A119 WeakPolarHBondContact O-CB 3.24Å; G115-A119 PolarHBondContact O-N 2.98Å; G115-A119 VanDerWaalsContact O-N 3.09Å; A119-K124 HydrophobicContact CB-CB 3.93Å; A119-A125 VanDerWaalsContact CB-CA 3.46Å; A119-A125 HydrophobicContact CB-CB 3.69Å; A119-A125 VanDerWaalsContact CB-N 3.32Å; A119-V128 HydrophobicContact CB-CG2 4.42Å
120D98.7Very high98.9Very high48 Ų4820.5 Ų20.526%0.25710%0.102SC..SBendtrans-101.42.6177.757.7-38.7000113.4Y65 H85 K124Y65-D120 HydrophobicContact CE2-CB 4.02Å; H85-D120 HydrophobicContact CB-CB 4.02Å; D120-K124 WeakPolarHBondContact OD1-CD 2.84Å; D120-K124 WeakPolarHBondContact OD1-CE 3.46Å; D120-K124 IonicContact OD1-NZ 2.85Å; D120-K124 PolarHBondContact OD1-NZ 3.05Å; D120-K124 IonicContact OD2-NZ 2.73Å; D120-K124 PolarHBondContact OD2-NZ 2.79Å
121T98.9Very high98.9Very high39 Ų3923.2 Ų23.224%0.23912%0.124CC..SBendtrans-146.3157.3175.261.40000110E123 K124 A125 D159T121-E123 PolarHBondContact O-N 2.77Å; T121-K124 PolarHBondContact O-N 2.68Å; T121-K124 VanDerWaalsContact OG1-CB 3.28Å; T121-K124 WeakPolarHBondContact OG1-CB 3.31Å; T121-K124 WeakPolarHBondContact OG1-CD 3.45Å; T121-K124 WeakPolarHBondContact OG1-CG 3.41Å; T121-K124 PolarHBondContact OG1-N 2.69Å; T121-A125 PolarHBondContact O-N 2.79Å; T121-D159 WeakPolarHBondContact CA-OD2 3.36Å
122A98.9Very high98.8Very high0 Ų023.7 Ų23.70%013%0.126CC..Hα-helixtrans-59.5-44.7176.800000112.1K124 A125 V126 I157 D159 E162A122-K124 PolarHBondContact O-N 3.19Å; A122-A125 WeakPolarHBondContact O-CB 3.47Å; A122-A125 PolarHBondContact O-N 2.68Å; A122-A125 VanDerWaalsContact O-N 3.12Å; A122-V126 PolarHBondContact O-N 2.97Å; A122-V126 VanDerWaalsContact O-N 3.13Å; A122-I157 HydrophobicContact CB-CG2 3.7Å; A122-D159 HydrophobicContact CB-CB 3.98Å; A122-D159 PolarHBondContact N-OD2 3.48Å; A122-E162 HydrophobicContact CB-CG 4.43Å
123E98.9Very high98.8Very high78 Ų7823.7 Ų23.736%0.36413%0.127SC..Hα-helixtrans-60.1-46.8177.6-175.4179.1-166.200112.4T121 A125 V126 D127 W164 K197T121-E123 PolarHBondContact O-N 2.77Å; E123-A125 PolarHBondContact O-N 3.39Å; E123-V126 VanDerWaalsContact O-CB 3.32Å; E123-V126 WeakPolarHBondContact O-CB 3.26Å; E123-V126 PolarHBondContact O-N 2.84Å; E123-V126 VanDerWaalsContact O-N 3.13Å; E123-D127 PolarHBondContact O-N 2.86Å; E123-D127 VanDerWaalsContact O-N 3.12Å; E123-W164 HydrophobicContact CB-CZ2 4.17Å; E123-W164 HydrophobicContact CG-CZ2 3.88Å; E123-K197 WeakPolarHBondContact OE1-CE 3.41Å; E123-K197 IonicContact OE1-NZ 3.81Å; E123-K197 PolarHBondContact OE1-NZ 2.81Å
124K98.9Very high98.7Very high94 Ų9429.4 Ų29.441%0.40915%0.154SC..Hα-helixtrans-62.3-31.9175.7-71.9172.7-175.8-179.30112.4A119 D120 T121 A122 V126 D127 V128A119-K124 HydrophobicContact CB-CB 3.93Å; D120-K124 WeakPolarHBondContact OD1-CD 2.84Å; D120-K124 WeakPolarHBondContact OD1-CE 3.46Å; D120-K124 IonicContact OD1-NZ 2.85Å; D120-K124 PolarHBondContact OD1-NZ 3.05Å; D120-K124 IonicContact OD2-NZ 2.73Å; D120-K124 PolarHBondContact OD2-NZ 2.79Å; T121-K124 PolarHBondContact O-N 2.68Å; T121-K124 VanDerWaalsContact OG1-CB 3.28Å; T121-K124 WeakPolarHBondContact OG1-CB 3.31Å; T121-K124 WeakPolarHBondContact OG1-CD 3.45Å; T121-K124 WeakPolarHBondContact OG1-CG 3.41Å; T121-K124 PolarHBondContact OG1-N 2.69Å; A122-K124 PolarHBondContact O-N 3.19Å; K124-V126 VanDerWaalsContact C-N 3.34Å; K124-D127 PolarHBondContact O-N 2.75Å; K124-V128 WeakPolarHBondContact O-CB 3.48Å; K124-V128 VanDerWaalsContact O-CG2 3.31Å; K124-V128 WeakPolarHBondContact O-CG2 3.32Å; K124-V128 PolarHBondContact O-N 2.79Å
125A98.9Very high98.6Very high0 Ų035.9 Ų35.90%018%0.182CC..Hα-helixtrans-65.9-38.7175.300000111.3V87 I89 A119 T121 A122 E123 D127 V128 I129 I157V87-A125 HydrophobicContact CG1-CB 4.33Å; I89-A125 HydrophobicContact CD1-CB 3.88Å; A119-A125 VanDerWaalsContact CB-CA 3.46Å; A119-A125 HydrophobicContact CB-CB 3.69Å; A119-A125 VanDerWaalsContact CB-N 3.32Å; T121-A125 PolarHBondContact O-N 2.79Å; A122-A125 WeakPolarHBondContact O-CB 3.47Å; A122-A125 PolarHBondContact O-N 2.68Å; A122-A125 VanDerWaalsContact O-N 3.12Å; E123-A125 PolarHBondContact O-N 3.39Å; A125-D127 VanDerWaalsContact C-N 3.34Å; A125-D127 PolarHBondContact O-N 2.82Å; A125-V128 PolarHBondContact O-N 3.15Å; A125-I129 WeakPolarHBondContact O-CB 3.42Å; A125-I129 VanDerWaalsContact O-CG1 3.27Å; A125-I129 WeakPolarHBondContact O-CG1 3.35Å; A125-I129 PolarHBondContact O-N 3.07Å; A125-I157 HydrophobicContact CB-CD1 4.42Å; A125-I157 HydrophobicContact CB-CG2 3.87Å
126V98.9Very high98.6Very high0 Ų038.3 Ų38.30%019%0.192CC..Hα-helixtrans-57.2-48.7170.61750000110.4A122 E123 K124 V128 I129 A130 I157 W164 L166 A175 K197A122-V126 PolarHBondContact O-N 2.97Å; A122-V126 VanDerWaalsContact O-N 3.13Å; E123-V126 VanDerWaalsContact O-CB 3.32Å; E123-V126 WeakPolarHBondContact O-CB 3.26Å; E123-V126 PolarHBondContact O-N 2.84Å; E123-V126 VanDerWaalsContact O-N 3.13Å; K124-V126 VanDerWaalsContact C-N 3.34Å; V126-V128 PolarHBondContact O-N 3.37Å; V126-I129 PolarHBondContact O-N 3.23Å; V126-A130 WeakPolarHBondContact O-CB 3.49Å; V126-A130 PolarHBondContact O-N 2.72Å; V126-I157 HydrophobicContact CG2-CD1 3.76Å; V126-W164 HydrophobicContact CG2-CB 3.65Å; V126-W164 HydrophobicContact CG2-CD2 4.1Å; V126-W164 HydrophobicContact CG2-CE3 4.3Å; V126-W164 HydrophobicContact CG2-CG 3.85Å; V126-L166 HydrophobicContact CG1-CD1 4.36Å; V126-L166 HydrophobicContact CG1-CD2 4.37Å; V126-A175 HydrophobicContact CG1-CB 3.92Å; V126-K197 HydrophobicContact CG1-CD 4.41Å
127D98.9Very high98.4Very high71 Ų7139.5 Ų39.538%0.3820%0.204SC..Hα-helixtrans-65-40.3-178.4-64.5-28.5000112.3E123 K124 A125 A130 A131 K197E123-D127 PolarHBondContact O-N 2.86Å; E123-D127 VanDerWaalsContact O-N 3.12Å; K124-D127 PolarHBondContact O-N 2.75Å; A125-D127 VanDerWaalsContact C-N 3.34Å; A125-D127 PolarHBondContact O-N 2.82Å; D127-A130 PolarHBondContact O-N 2.86Å; D127-A131 WeakPolarHBondContact O-CB 3.24Å; D127-A131 PolarHBondContact O-N 3.09Å; D127-K197 VanDerWaalsContact CG-NZ 3.28Å; D127-K197 IonicContact OD1-NZ 2.82Å; D127-K197 PolarHBondContact OD1-NZ 3.28Å; D127-K197 IonicContact OD2-NZ 3.9Å; D127-K197 PolarHBondContact OD2-NZ 2.88Å; D127-K197 VanDerWaalsContact OD2-NZ 3.1Å
128V98.9Very high98.3Very high29 Ų2940.4 Ų40.418%0.17621%0.208CC..Hα-helixtrans-60.9-49.8174.9164.40000110.8R118 A119 K124 A125 V126 A131 L132R118-V128 HydrophobicContact CB-CG1 4.03Å; R118-V128 HydrophobicContact CB-CG2 4.16Å; A119-V128 HydrophobicContact CB-CG2 4.42Å; K124-V128 WeakPolarHBondContact O-CB 3.48Å; K124-V128 VanDerWaalsContact O-CG2 3.31Å; K124-V128 WeakPolarHBondContact O-CG2 3.32Å; K124-V128 PolarHBondContact O-N 2.79Å; A125-V128 PolarHBondContact O-N 3.15Å; V126-V128 PolarHBondContact O-N 3.37Å; V128-A131 PolarHBondContact O-N 3.37Å; V128-L132 HydrophobicContact CG1-CD1 3.73Å; V128-L132 HydrophobicContact CG1-CG 4.5Å; V128-L132 WeakPolarHBondContact O-CB 3.3Å; V128-L132 VanDerWaalsContact O-CG 3.28Å; V128-L132 WeakPolarHBondContact O-CG 3.47Å; V128-L132 PolarHBondContact O-N 2.81Å
129I98.9Very high98.2Very high0 Ų039 Ų390%021%0.205CC..Hα-helixtrans-63.5-44.3-179-68.5168000110.1I89 L111 A125 V126 A131 L132 L133 F155 I157 L166I89-I129 HydrophobicContact CD1-CD1 4.42Å; L111-I129 HydrophobicContact CB-CG1 4.4Å; L111-I129 HydrophobicContact CB-CG2 4.17Å; L111-I129 HydrophobicContact CD1-CG2 4.19Å; L111-I129 HydrophobicContact CD2-CG2 4.39Å; L111-I129 HydrophobicContact CG-CG2 4.49Å; A125-I129 WeakPolarHBondContact O-CB 3.42Å; A125-I129 VanDerWaalsContact O-CG1 3.27Å; A125-I129 WeakPolarHBondContact O-CG1 3.35Å; A125-I129 PolarHBondContact O-N 3.07Å; V126-I129 PolarHBondContact O-N 3.23Å; I129-A131 PolarHBondContact O-N 2.89Å; I129-L132 PolarHBondContact O-N 3.01Å; I129-L133 WeakPolarHBondContact O-CB 3.44Å; I129-L133 PolarHBondContact O-N 2.83Å; I129-F155 HydrophobicContact CD1-CD1 4.45Å; I129-F155 HydrophobicContact CG2-CE2 4.22Å; I129-F155 HydrophobicContact CG2-CZ 4.41Å; I129-I157 HydrophobicContact CD1-CD1 3.93Å; I129-L166 HydrophobicContact CB-CD2 3.87Å; I129-L166 HydrophobicContact CD1-CD2 4.41Å; I129-L166 HydrophobicContact CG2-CD2 3.53Å
130A98.8Very high98Very high8 Ų839.2 Ų39.27%0.06621%0.208CC..Hα-helixtrans-59.1-45.6176.900000112.4V126 D127 L133 E134 W173V126-A130 WeakPolarHBondContact O-CB 3.49Å; V126-A130 PolarHBondContact O-N 2.72Å; D127-A130 PolarHBondContact O-N 2.86Å; A130-L133 PolarHBondContact O-N 3.12Å; A130-E134 PolarHBondContact O-N 2.87Å; A130-W173 HydrophobicContact CB-CD2 4.22Å; A130-W173 HydrophobicContact CB-CH2 4.21Å; A130-W173 HydrophobicContact CB-CZ2 3.54Å
131A98.6Very high97.7Very high56 Ų5638 Ų3846%0.46320%0.203SC..Hα-helixtrans-66.5-37.917900000112.6D127 V128 I129 K135D127-A131 WeakPolarHBondContact O-CB 3.24Å; D127-A131 PolarHBondContact O-N 3.09Å; V128-A131 PolarHBondContact O-N 3.37Å; I129-A131 PolarHBondContact O-N 2.89Å; A131-K135 WeakPolarHBondContact O-CB 3.34Å; A131-K135 PolarHBondContact O-N 2.96Å; A131-K135 VanDerWaalsContact O-N 3.08Å
132L98.6Very high97.4Very high10 Ų1036.2 Ų36.25%0.05219%0.192CC..Hα-helixtrans-67.1-42.5175.2-73.8167.7000111.6I58 L106 L111 L114 V128 I129 K135 Y136I58-L132 HydrophobicContact CD1-CD2 3.91Å; L106-L132 HydrophobicContact CD1-CB 4.05Å; L106-L132 HydrophobicContact CD1-CD2 4.38Å; L111-L132 HydrophobicContact CD2-CB 3.63Å; L111-L132 HydrophobicContact CD2-CD1 4.15Å; L114-L132 HydrophobicContact CB-CD1 3.59Å; L114-L132 HydrophobicContact CD1-CD1 3.85Å; L114-L132 HydrophobicContact CG-CD1 4.26Å; V128-L132 HydrophobicContact CG1-CD1 3.73Å; V128-L132 HydrophobicContact CG1-CG 4.5Å; V128-L132 WeakPolarHBondContact O-CB 3.3Å; V128-L132 VanDerWaalsContact O-CG 3.28Å; V128-L132 WeakPolarHBondContact O-CG 3.47Å; V128-L132 PolarHBondContact O-N 2.81Å; I129-L132 PolarHBondContact O-N 3.01Å; L132-K135 PolarHBondContact O-N 2.94Å; L132-Y136 HydrophobicContact CD2-CD2 3.82Å; L132-Y136 HydrophobicContact CD2-CE2 3.9Å; L132-Y136 WeakPolarHBondContact O-CB 3.31Å; L132-Y136 PolarHBondContact O-N 3.21Å
133L97.4Very high97.1Very high1 Ų137.5 Ų37.51%0.00520%0.198CC..Hα-helixtrans-62-42.9176.1-179.564000111.6I129 A130 G137 Q138 T168 W173I129-L133 WeakPolarHBondContact O-CB 3.44Å; I129-L133 PolarHBondContact O-N 2.83Å; A130-L133 PolarHBondContact O-N 3.12Å; L133-G137 WeakPolarHBondContact O-CA 3.5Å; L133-G137 PolarHBondContact O-N 3.42Å; L133-Q138 HydrophobicContact CD1-CB 3.68Å; L133-Q138 HydrophobicContact CD1-CG 3.59Å; L133-T168 HydrophobicContact CD2-CG2 3.8Å; L133-W173 HydrophobicContact CD2-CB 4.44Å
134E97Very high96.8Very high139 Ų13934.1 Ų34.165%0.6518%0.182SC*.Hα-helixtrans-63-42.7176.7-178.5173.3-167.100112.1A130A130-E134 PolarHBondContact O-N 2.87Å
135K97.7Very high96.3Very high137 Ų13732.8 Ų32.860%0.59618%0.18SC*.Hα-helixtrans-81.6-39.7-173.8-172.8173.2179.4-1670113.8A131 L132A131-K135 WeakPolarHBondContact O-CB 3.34Å; A131-K135 PolarHBondContact O-N 2.96Å; A131-K135 VanDerWaalsContact O-N 3.08Å; L132-K135 PolarHBondContact O-N 2.94Å
136Y97.7Very high95.6Very high51 Ų5138.7 Ų38.720%0.221%0.208CC..Hα-helixtrans-118.2-9-169.5-60-68.7000113.8I56 I58 E59 A105 L106 L132I56-Y136 HydrophobicContact CD1-CD1 4.47Å; I58-Y136 HydrophobicContact CB-CD1 4.34Å; I58-Y136 HydrophobicContact CB-CD2 4.27Å; I58-Y136 HydrophobicContact CB-CE1 3.94Å; I58-Y136 HydrophobicContact CB-CE2 3.85Å; I58-Y136 HydrophobicContact CB-CG 4.5Å; I58-Y136 HydrophobicContact CD1-CE2 4.43Å; I58-Y136 HydrophobicContact CG2-CD1 3.64Å; I58-Y136 HydrophobicContact CG2-CD2 3.86Å; I58-Y136 HydrophobicContact CG2-CE1 3.74Å; I58-Y136 HydrophobicContact CG2-CE2 3.95Å; I58-Y136 HydrophobicContact CG2-CG 3.7Å; E59-Y136 WeakPolarHBondContact CG-OH 3.4Å; E59-Y136 PolarHBondContact N-OH 2.88Å; A105-Y136 WeakPolarHBondContact CB-O 3.39Å; L106-Y136 HydrophobicContact CD1-CD2 4.23Å; L106-Y136 HydrophobicContact CD1-CG 4.36Å; L132-Y136 HydrophobicContact CD2-CD2 3.82Å; L132-Y136 HydrophobicContact CD2-CE2 3.9Å; L132-Y136 WeakPolarHBondContact O-CB 3.31Å; L132-Y136 PolarHBondContact O-N 3.21Å
137G96.3Very high94.7Very high24 Ų2442 Ų4225%0.24723%0.231CC..  trans70.6-174.6-177.800000113.4L133L133-G137 WeakPolarHBondContact O-CA 3.5Å; L133-G137 PolarHBondContact O-N 3.42Å
138Q96.7Very high93.9Very high25 Ų2546.6 Ų46.612%0.11725%0.25CC..BIsolated β-bridgetrans-136143.3170.366.2179-5500110.4L106 L133 T168 G170L106-Q138 CarbonylContact O-C 3.31Å; L106-Q138 WeakPolarHBondContact O-CA 3.16Å; L133-Q138 HydrophobicContact CD1-CB 3.68Å; L133-Q138 HydrophobicContact CD1-CG 3.59Å; Q138-T168 PolarHBondContact NE2-OG1 3.37Å; Q138-T168 PolarHBondContact OE1-OG1 2.59Å; Q138-G170 PolarHBondContact NE2-O 3.26Å
139G95.4Very high93.5Very high9 Ų946.3 Ų46.39%0.09325%0.246CC..  trans158.7167.1-176.700000114.9A105 L106A105-G139 CarbonylContact C-O 3.5Å; A105-G139 PolarHBondContact N-O 2.86Å; L106-G139 PolarHBondContact O-N 2.95Å; L106-G139 VanDerWaalsContact O-N 3.1Å
140G94.2Very high93.2Very high5 Ų547.2 Ų47.25%0.05225%0.252CS..SBendtrans109.6164.7-174.600000112.9C142G140-C142 PolarHBondContact O-N 2.71Å
141S93.8Very high92.9Very high21 Ų2147.5 Ų47.515%0.14725%0.251CS..  trans-66.4133.3-180-171.60000110.9Y55 M143 S147 F149Y55-S141 VanDerWaalsContact CE2-O 3.29Å; Y55-S141 WeakPolarHBondContact CE2-O 3.4Å; Y55-S141 VanDerWaalsContact CZ-O 3.32Å; Y55-S141 PolarHBondContact OH-O 3.13Å; S141-M143 VanDerWaalsContact C-N 3.35Å; S141-M143 PolarHBondContact OG-O 3.29Å; S141-S147 PolarHBondContact OG-O 2.9Å; S141-F149 PolarHBondContact OG-N 2.65Å
142C93.1Very high92.8Very high2 Ų245 Ų451%0.01423%0.23CC..  trans-97.319.7178.9-61.90000112.1R29 M109 G140 F149 Y151R29-C142 PolarHBondContact NH1-O 3.19Å; R29-C142 PolarHBondContact NH2-O 3.04Å; M109-C142 HydrophobicContact CE-CB 4.08Å; G140-C142 PolarHBondContact O-N 2.71Å; C142-F149 HydrophobicContact CB-CD1 4.19Å; C142-F149 VanDerWaalsContact CB-O 3.28Å; C142-F149 WeakPolarHBondContact CB-O 3.34Å; C142-F149 PolarHBondContact N-O 2.89Å; C142-Y151 HydrophobicContact CB-CD1 3.95Å; C142-Y151 HydrophobicContact CB-CE1 3.2Å; C142-Y151 HydrophobicContact CB-CE2 4.28Å; C142-Y151 VanDerWaalsContact CB-CZ 3.42Å; C142-Y151 WeakPolarHBondContact CB-OH 3.43Å; C142-Y151 VanDerWaalsContact SG-CE1 3.54Å
143M91.6Very high92.7Very high27 Ų2744.6 Ų44.613%0.13323%0.228CC..SBendtrans-139.9144.4-178.2-171.5179.1-54.300111.2P30 S141 D145 F149 F275 F340P30-M143 HydrophobicContact CG-CE 3.9Å; P30-M143 HydrophobicContact CG-CG 3.92Å; P30-M143 HydrophobicContact CG-SD 3.86Å; S141-M143 VanDerWaalsContact C-N 3.35Å; S141-M143 PolarHBondContact OG-O 3.29Å; M143-D145 HydrophobicContact CG-CB 4.07Å; M143-D145 PolarHBondContact O-N 2.98Å; M143-D145 HydrophobicContact SD-CB 4.01Å; M143-F149 HydrophobicContact CB-CB 4.07Å; M143-F149 HydrophobicContact CB-CD1 4.36Å; M143-F149 HydrophobicContact CE-CB 3.99Å; M143-F149 HydrophobicContact CE-CD1 3.77Å; M143-F149 HydrophobicContact CE-CE1 4.47Å; M143-F149 HydrophobicContact CE-CG 3.83Å; M143-F275 HydrophobicContact CE-CE1 4.44Å; M143-F275 HydrophobicContact CE-CE2 4.34Å; M143-F275 HydrophobicContact CE-CZ 3.54Å; M143-F340 WeakPolarHBondContact O-CE2 3.31Å
144E92.4Very high92.7Very high7 Ų744.6 Ų44.63%0.03323%0.228CC..SBendtrans-77.564.9171.1-165.5-179.5-157.400111.4E33 W74 F340 K343 R346E33-E144 PolarHBondContact OE1-N 2.97Å; W74-E144 HydrophobicContact CB-CB 4.27Å; W74-E144 HydrophobicContact CB-CG 4.11Å; W74-E144 HydrophobicContact CD2-CB 3.97Å; W74-E144 HydrophobicContact CG-CB 3.73Å; W74-E144 HydrophobicContact CG-CG 4.11Å; E144-F340 HydrophobicContact CB-CD1 4.37Å; E144-F340 HydrophobicContact CB-CE1 4.35Å; E144-F340 HydrophobicContact CG-CD1 3.66Å; E144-F340 HydrophobicContact CG-CE1 3.9Å; E144-K343 HydrophobicContact CG-CG 4.41Å; E144-R346 IonicContact OE1-CZ 3.05Å; E144-R346 IonicContact OE1-NE 3.74Å; E144-R346 PolarHBondContact OE1-NE 2.88Å; E144-R346 IonicContact OE1-NH2 2.79Å; E144-R346 PolarHBondContact OE1-NH2 3.17Å; E144-R346 IonicContact OE2-NE 3.82Å; E144-R346 PolarHBondContact OE2-NE 2.87Å
145D87.6Confident92.8Very high66 Ų6638 Ų3835%0.35320%0.197SC..SBendtrans-151164.7177.5-173.227000110.8M143 S147 F340M143-D145 HydrophobicContact CG-CB 4.07Å; M143-D145 PolarHBondContact O-N 2.98Å; M143-D145 HydrophobicContact SD-CB 4.01Å; D145-S147 PolarHBondContact O-N 3Å; D145-S147 WeakPolarHBondContact OD2-CB 3.43Å; D145-S147 PolarHBondContact OD2-N 2.81Å; D145-S147 PolarHBondContact OD2-OG 3Å; D145-F340 VanDerWaalsContact O-CD2 3.23Å; D145-F340 WeakPolarHBondContact O-CD2 3.5Å
146Q84.2Confident92.8Very high125 Ų12531.4 Ų31.458%0.58417%0.168SC*.SBendtrans-72.8-17.8172.6-60.8-175.516.600112.6F340Q146-F340 WeakPolarHBondContact CG-O 3.24Å
147S81.8Confident92.9Very high70 Ų7029 Ų2949%0.4916%0.159SC..SBendtrans-69.2129.8174.1-53.50000110.4S141 D145 F149S141-S147 PolarHBondContact OG-O 2.9Å; D145-S147 PolarHBondContact O-N 3Å; D145-S147 WeakPolarHBondContact OD2-CB 3.43Å; D145-S147 PolarHBondContact OD2-N 2.81Å; D145-S147 PolarHBondContact OD2-OG 3Å; S147-F149 PolarHBondContact O-N 2.67Å
148E81.8Confident93Very high166 Ų16628 Ų2878%0.77615%0.148SC*.  trans-69.6118.4172.6-70.3-175.8163.900109.9
149F89Confident93.1Very high24 Ų2427.3 Ų27.311%0.10515%0.145CC..  trans-128.189.6174.4-174-118.5000110.4P3 W95 S141 C142 M143 S147 Y151P3-F149 HydrophobicContact CB-CE1 4.48Å; P3-F149 HydrophobicContact CB-CE2 4.18Å; P3-F149 HydrophobicContact CB-CZ 3.78Å; P3-F149 HydrophobicContact CG-CD2 3.91Å; P3-F149 HydrophobicContact CG-CE1 4.02Å; P3-F149 HydrophobicContact CG-CE2 3Å; P3-F149 HydrophobicContact CG-CZ 3.06Å; W95-F149 HydrophobicContact CH2-CE2 4.4Å; W95-F149 AromaticContact CH2-CZ 3.99Å; W95-F149 HydrophobicContact CH2-CZ 3.99Å; W95-F149 AromaticContact CZ2-CE2 3.72Å; W95-F149 HydrophobicContact CZ2-CE2 3.72Å; W95-F149 AromaticContact CZ2-CZ 3.6Å; W95-F149 HydrophobicContact CZ2-CZ 3.6Å; S141-F149 PolarHBondContact OG-N 2.65Å; C142-F149 HydrophobicContact CB-CD1 4.19Å; C142-F149 VanDerWaalsContact CB-O 3.28Å; C142-F149 WeakPolarHBondContact CB-O 3.34Å; C142-F149 PolarHBondContact N-O 2.89Å; M143-F149 HydrophobicContact CB-CB 4.07Å; M143-F149 HydrophobicContact CB-CD1 4.36Å; M143-F149 HydrophobicContact CE-CB 3.99Å; M143-F149 HydrophobicContact CE-CD1 3.77Å; M143-F149 HydrophobicContact CE-CE1 4.47Å; M143-F149 HydrophobicContact CE-CG 3.83Å; S147-F149 PolarHBondContact O-N 2.67Å; F149-Y151 HydrophobicContact CD1-CD1 4.26Å; F149-Y151 HydrophobicContact CD1-CE1 4.07Å; F149-Y151 AromaticContact CE1-CD1 3.74Å; F149-Y151 HydrophobicContact CE1-CD1 3.74Å; F149-Y151 AromaticContact CE1-CE1 3.55Å; F149-Y151 HydrophobicContact CE1-CE1 3.55Å; F149-Y151 AromaticContact CZ-CD1 3.95Å; F149-Y151 HydrophobicContact CZ-CD1 3.95Å; F149-Y151 HydrophobicContact CZ-CE1 4.19Å
150T92.8Very high93.2Very high19 Ų1928.9 Ų28.912%0.11715%0.148CC..  trans-107.2148.1-174530000111.3W95 A100 D101W95-T150 PolarHBondContact NE1-O 2.9Å; A100-T150 WeakPolarHBondContact O-CB 3.45Å; D101-T150 PolarHBondContact OD1-OG1 3.34Å
151Y94Very high93.4Very high13 Ų1336.7 Ų36.75%0.05118%0.181CC..  trans-159.9164.7173.951.2-108.2000111.1A93 W95 A100 M109 C142 F149 N153A93-Y151 HydrophobicContact CB-CD1 3.46Å; A93-Y151 VanDerWaalsContact CB-CD1 3.46Å; A93-Y151 HydrophobicContact CB-CD2 3.61Å; A93-Y151 HydrophobicContact CB-CE1 3.7Å; A93-Y151 HydrophobicContact CB-CE2 3.87Å; A93-Y151 HydrophobicContact CB-CG 3.38Å; W95-Y151 HydrophobicContact CZ2-CD1 4.08Å; W95-Y151 HydrophobicContact CZ2-CG 4.37Å; A100-Y151 VanDerWaalsContact CB-C 3.47Å; A100-Y151 VanDerWaalsContact CB-CA 3.44Å; M109-Y151 HydrophobicContact SD-CE2 4.17Å; M109-Y151 PolarHBondContact SD-OH 2.98Å; C142-Y151 HydrophobicContact CB-CD1 3.95Å; C142-Y151 HydrophobicContact CB-CE1 3.2Å; C142-Y151 HydrophobicContact CB-CE2 4.28Å; C142-Y151 VanDerWaalsContact CB-CZ 3.42Å; C142-Y151 WeakPolarHBondContact CB-OH 3.43Å; C142-Y151 VanDerWaalsContact SG-CE1 3.54Å; F149-Y151 HydrophobicContact CD1-CD1 4.26Å; F149-Y151 HydrophobicContact CD1-CE1 4.07Å; F149-Y151 AromaticContact CE1-CD1 3.74Å; F149-Y151 HydrophobicContact CE1-CD1 3.74Å; F149-Y151 AromaticContact CE1-CE1 3.55Å; F149-Y151 HydrophobicContact CE1-CE1 3.55Å; F149-Y151 AromaticContact CZ-CD1 3.95Å; F149-Y151 HydrophobicContact CZ-CD1 3.95Å; F149-Y151 HydrophobicContact CZ-CE1 4.19Å; Y151-N153 WeakPolarHBondContact CE2-ND2 3.32Å
152H95.6Very high93.6Very high5 Ų536.4 Ų36.42%0.02318%0.177CC..EExtended strand (participates in β ladder)trans-93.5179.2162-60.8136.3000110.1V94 E98 S99 T168 G170V94-H152 HydrophobicContact CG2-CB 4.07Å; V94-H152 WeakPolarHBondContact CG2-O 3.17Å; V94-H152 PolarHBondContact N-O 2.94Å; V94-H152 PolarHBondContact O-N 3.27Å; V94-H152 VanDerWaalsContact O-N 3.08Å; E98-H152 PolarHBondContact O-CE1 3.46Å; S99-H152 PolarHBondContact O-CE1 3.11Å; S99-H152 PolarHBondContact O-NE2 3.09Å; H152-T168 WeakPolarHBondContact CB-O 3.44Å; H152-G170 PolarHBondContact CE1-N 3.17Å; H152-G170 PolarHBondContact ND1-N 3.46Å; H152-G170 WeakPolarHBondContact NE2-CA 3.46Å; H152-G170 PolarHBondContact NE2-N 2.9Å
153N96.4Very high93.9Very high1 Ų136.3 Ų36.31%0.00518%0.176CC..EExtended strand (participates in β ladder)trans-124140.4-174-72.992000114.9N91 E92 G108 Y151 F155 T168N91-N153 PolarHBondContact ND2-ND2 2.95Å; E92-N153 VanDerWaalsContact O-CA 3.29Å; E92-N153 WeakPolarHBondContact O-CA 3.16Å; E92-N153 PolarHBondContact O-ND2 3.34Å; G108-N153 WeakPolarHBondContact CA-OD1 3.22Å; Y151-N153 WeakPolarHBondContact CE2-ND2 3.32Å; N153-F155 HydrophobicContact CB-CD2 4.15Å; N153-F155 HydrophobicContact CB-CE1 4.14Å; N153-F155 HydrophobicContact CB-CE2 3.4Å; N153-F155 VanDerWaalsContact CB-CE2 3.4Å; N153-F155 HydrophobicContact CB-CZ 3.4Å; N153-T168 PolarHBondContact N-OG1 3.23Å; N153-T168 PolarHBondContact O-N 2.88Å; N153-T168 PolarHBondContact O-OG1 2.91Å
154S97.7Very high94.2Very high0 Ų035.3 Ų35.30%017%0.171CC..EExtended strand (participates in β ladder)trans-99.2140.6154.8-175.80000108N91 E92 L166 E167N91-S154 CarbonylContact C-O 3.46Å; N91-S154 WeakPolarHBondContact CA-O 3.46Å; E92-S154 PolarHBondContact N-O 2.9Å; E92-S154 PolarHBondContact O-N 3.19Å; S154-L166 CarbonylContact C-O 3.4Å; S154-L166 WeakPolarHBondContact CA-O 3.32Å; S154-E167 WeakPolarHBondContact OG-CG 3.37Å; S154-E167 PolarHBondContact OG-OE1 3.01Å
155F98.8Very high94.5Very high0 Ų035 Ų350%017%0.17CC..EExtended strand (participates in β ladder)trans-125.4134.9178.7-56.7-93.3000108.8I89 G90 N91 G108 L111 V112 I129 N153 I157 V165 L166 T168I89-F155 HydrophobicContact CG2-CD1 4.39Å; G90-F155 CarbonylContact O-C 3.57Å; G90-F155 WeakPolarHBondContact O-CA 3.4Å; N91-F155 HydrophobicContact CB-CD1 3.61Å; N91-F155 HydrophobicContact CB-CE1 3.77Å; N91-F155 HydrophobicContact CB-CG 4.45Å; G108-F155 WeakPolarHBondContact O-CE1 3.35Å; L111-F155 HydrophobicContact CB-CE1 4.18Å; L111-F155 HydrophobicContact CB-CZ 3.99Å; L111-F155 HydrophobicContact CD1-CZ 4.09Å; V112-F155 HydrophobicContact CG2-CD1 3.98Å; V112-F155 HydrophobicContact CG2-CE1 3.83Å; I129-F155 HydrophobicContact CD1-CD1 4.45Å; I129-F155 HydrophobicContact CG2-CE2 4.22Å; I129-F155 HydrophobicContact CG2-CZ 4.41Å; N153-F155 HydrophobicContact CB-CD2 4.15Å; N153-F155 HydrophobicContact CB-CE1 4.14Å; N153-F155 HydrophobicContact CB-CE2 3.4Å; N153-F155 VanDerWaalsContact CB-CE2 3.4Å; N153-F155 HydrophobicContact CB-CZ 3.4Å; F155-I157 HydrophobicContact CB-CD1 4.28Å; F155-I157 HydrophobicContact CB-CG1 4.15Å; F155-V165 CarbonylContact O-C 3.6Å; F155-V165 WeakPolarHBondContact O-CA 3.48Å; F155-L166 HydrophobicContact CB-CB 4.29Å; F155-L166 HydrophobicContact CD2-CB 4.39Å; F155-L166 HydrophobicContact CD2-CD2 4.12Å; F155-L166 HydrophobicContact CD2-CG 4.12Å; F155-L166 PolarHBondContact N-O 3.43Å; F155-L166 PolarHBondContact O-N 2.9Å; F155-T168 HydrophobicContact CE2-CG2 4Å
156L98.9Very high95.1Very high0 Ų031.9 Ų31.90%015%0.153CC..EExtended strand (participates in β ladder)trans-107.4120.9163.9-170.267000108T8 F9 V10 F23 I89 G90 V165 R183 I185T8-L156 HydrophobicContact CG2-CB 3.67Å; T8-L156 HydrophobicContact CG2-CD2 3.74Å; T8-L156 HydrophobicContact CG2-CG 4.27Å; F9-L156 VanDerWaalsContact C-CD2 3.47Å; V10-L156 HydrophobicContact CB-CD2 3.81Å; V10-L156 HydrophobicContact CB-CG 4.47Å; V10-L156 HydrophobicContact CG1-CD1 4.11Å; V10-L156 HydrophobicContact CG1-CD2 3.86Å; V10-L156 HydrophobicContact CG1-CG 4.34Å; F23-L156 HydrophobicContact CE2-CB 4.23Å; F23-L156 HydrophobicContact CE2-CD2 4.12Å; F23-L156 HydrophobicContact CE2-CG 4.1Å; F23-L156 WeakPolarHBondContact CE2-O 3.46Å; I89-L156 WeakPolarHBondContact CA-O 3.31Å; G90-L156 PolarHBondContact N-O 2.7Å; G90-L156 PolarHBondContact O-N 2.8Å; L156-V165 HydrophobicContact CD1-CG2 3.73Å; L156-R183 HydrophobicContact CD1-CG 4.4Å; L156-I185 HydrophobicContact CB-CD1 3.73Å; L156-I185 HydrophobicContact CB-CG1 4.03Å
157I98.9Very high95.8Very high0 Ų025.9 Ų25.90%013%0.125CC..EExtended strand (participates in β ladder)trans-121.8133.2-173.2-56.8171.8000106.4V87 C88 I89 A122 A125 V126 I129 F155 A163 W164V87-I157 HydrophobicContact CG1-CG2 4.22Å; C88-I157 CarbonylContact O-C 3.58Å; C88-I157 WeakPolarHBondContact O-CA 3.44Å; I89-I157 HydrophobicContact CD1-CG1 4.35Å; I89-I157 HydrophobicContact CD1-CG2 4.34Å; I89-I157 HydrophobicContact CG1-CB 4.44Å; I89-I157 HydrophobicContact CG1-CG1 4.12Å; I89-I157 HydrophobicContact CG1-CG2 4.03Å; I89-I157 HydrophobicContact CG2-CG1 4.11Å; A122-I157 HydrophobicContact CB-CG2 3.7Å; A125-I157 HydrophobicContact CB-CD1 4.42Å; A125-I157 HydrophobicContact CB-CG2 3.87Å; V126-I157 HydrophobicContact CG2-CD1 3.76Å; I129-I157 HydrophobicContact CD1-CD1 3.93Å; F155-I157 HydrophobicContact CB-CD1 4.28Å; F155-I157 HydrophobicContact CB-CG1 4.15Å; I157-A163 CarbonylContact O-C 3.5Å; I157-A163 WeakPolarHBondContact O-CA 3.01Å; I157-A163 WeakPolarHBondContact O-CB 3.37Å; I157-W164 HydrophobicContact CB-CB 4.36Å; I157-W164 PolarHBondContact N-O 3.27Å; I157-W164 PolarHBondContact O-N 2.59Å
158S98.9Very high96.5Very high2 Ų222.6 Ų22.61%0.01410%0.102CC..EExtended strand (participates in β ladder)trans-140.9156.2176.959.50000111.8F23 V87 C88 E162F23-S158 WeakPolarHBondContact CD2-OG 3.43Å; V87-S158 CarbonylContact C-O 3.57Å; V87-S158 VanDerWaalsContact CA-O 3.29Å; V87-S158 WeakPolarHBondContact CA-O 3.48Å; C88-S158 PolarHBondContact N-O 3.18Å; C88-S158 PolarHBondContact O-N 2.78Å; S158-E162 WeakPolarHBondContact CA-O 2.87Å
159D98.8Very high97.2Very high12 Ų1214.7 Ų14.76%0.0647%0.065CC..  trans-137.4-157.8169.76824.8000110.5I21 V87 T121 A122 K161 E162I21-D159 WeakPolarHBondContact CG1-O 3.22Å; V87-D159 HydrophobicContact CG2-CB 4.35Å; T121-D159 WeakPolarHBondContact CA-OD2 3.36Å; A122-D159 HydrophobicContact CB-CB 3.98Å; A122-D159 PolarHBondContact N-OD2 3.48Å; D159-K161 PolarHBondContact O-N 3Å; D159-K161 PolarHBondContact OD1-N 3.29Å; D159-E162 PolarHBondContact N-O 2.94Å; D159-E162 PolarHBondContact OD1-N 3.24Å; D159-E162 VanDerWaalsContact OD1-N 3.08Å
160R97.3Very high97.4Very high42 Ų4214.3 Ų14.316%0.1587%0.068CC..SBendtrans-70.3-7.2-179.4-69177.9-179-89.714115I21 Q86 V285 P286 N288 L291I21-R160 VanDerWaalsContact CD1-C 3.43Å; I21-R160 WeakPolarHBondContact CD1-O 3.4Å; Q86-R160 HydrophobicContact CB-CG 4.27Å; Q86-R160 VanDerWaalsContact CG-CZ 3.46Å; R160-V285 HydrophobicContact CB-CG1 4.27Å; R160-V285 HydrophobicContact CG-CG1 3.36Å; R160-P286 PolarHBondContact NH1-O 3.17Å; R160-N288 PolarHBondContact NH1-O 3.19Å; R160-L291 PolarHBondContact NH1-O 2.99Å; R160-L291 PolarHBondContact NH2-O 2.84Å
161K97.8Very high97.5Very high168 Ų16818.7 Ų18.773%0.739%0.086SC*.SBendtrans-127.8-39.2-170.4-63.6179.2-177.6174.50112.5D159D159-K161 PolarHBondContact O-N 3Å; D159-K161 PolarHBondContact OD1-N 3.29Å
162E98.6Very high97.6Very high15 Ų1519.3 Ų19.37%0.079%0.088CC..  trans-150.7169.7-166.961.7-172.9-16000111.6A122 S158 D159 W164 R177A122-E162 HydrophobicContact CB-CG 4.43Å; S158-E162 WeakPolarHBondContact CA-O 2.87Å; D159-E162 PolarHBondContact N-O 2.94Å; D159-E162 PolarHBondContact OD1-N 3.24Å; D159-E162 VanDerWaalsContact OD1-N 3.08Å; E162-W164 PolarHBondContact OE1-NE1 3.25Å; E162-R177 IonicContact OE2-CZ 2.67Å; E162-R177 IonicContact OE2-NE 3.14Å; E162-R177 PolarHBondContact OE2-NE 3.36Å; E162-R177 IonicContact OE2-NH2 2.7Å; E162-R177 PolarHBondContact OE2-NH2 3.14Å
163A98.8Very high97.8Very high0 Ų020.2 Ų20.20%09%0.091CC..EExtended strand (participates in β ladder)trans-128.2160167.200000110.8V10 L12 I157 V178V10-A163 HydrophobicContact CB-CB 4.46Å; V10-A163 HydrophobicContact CG1-CB 3.79Å; V10-A163 HydrophobicContact CG2-CB 4.11Å; L12-A163 HydrophobicContact CD1-CB 4.03Å; I157-A163 CarbonylContact O-C 3.5Å; I157-A163 WeakPolarHBondContact O-CA 3.01Å; I157-A163 WeakPolarHBondContact O-CB 3.37Å; A163-V178 HydrophobicContact CB-CB 4.26Å; A163-V178 PolarHBondContact N-O 2.8Å; A163-V178 PolarHBondContact O-N 2.65Å
164W98.9Very high97.9Very high6 Ų620.2 Ų20.22%0.0239%0.091CC..EExtended strand (participates in β ladder)trans-135.8133.7179.3-73.284000109.2E123 V126 I157 E162 A175 E176 R177 D196 K197E123-W164 HydrophobicContact CB-CZ2 4.17Å; E123-W164 HydrophobicContact CG-CZ2 3.88Å; V126-W164 HydrophobicContact CG2-CB 3.65Å; V126-W164 HydrophobicContact CG2-CD2 4.1Å; V126-W164 HydrophobicContact CG2-CE3 4.3Å; V126-W164 HydrophobicContact CG2-CG 3.85Å; I157-W164 HydrophobicContact CB-CB 4.36Å; I157-W164 PolarHBondContact N-O 3.27Å; I157-W164 PolarHBondContact O-N 2.59Å; E162-W164 PolarHBondContact OE1-NE1 3.25Å; W164-A175 HydrophobicContact CE3-CB 4Å; W164-A175 HydrophobicContact CZ3-CB 4.22Å; W164-E176 WeakPolarHBondContact CA-O 3.31Å; W164-R177 HydrophobicContact CD2-CB 4.07Å; W164-R177 HydrophobicContact CD2-CG 4.19Å; W164-R177 HydrophobicContact CE3-CB 3.96Å; W164-R177 HydrophobicContact CH2-CB 3.75Å; W164-R177 HydrophobicContact CH2-CG 4.08Å; W164-R177 HydrophobicContact CZ2-CB 3.84Å; W164-R177 HydrophobicContact CZ2-CG 3.65Å; W164-R177 HydrophobicContact CZ3-CB 3.8Å; W164-D196 HydrophobicContact CH2-CB 4.01Å; W164-D196 HydrophobicContact CZ3-CB 3.76Å; W164-K197 HydrophobicContact CH2-CD 4.19Å; W164-K197 HydrophobicContact CH2-CG 4.19Å; W164-K197 HydrophobicContact CZ3-CD 4.24Å; W164-K197 HydrophobicContact CZ3-CG 4.12Å
165V98.9Very high98Very high0 Ų020.2 Ų20.20%09%0.091CC..EExtended strand (participates in β ladder)trans-95.4127162.4-1780000107F155 L156 E167 A175 E176 R183 I185 I191F155-V165 CarbonylContact O-C 3.6Å; F155-V165 WeakPolarHBondContact O-CA 3.48Å; L156-V165 HydrophobicContact CD1-CG2 3.73Å; V165-E167 HydrophobicContact CG1-CG 4.02Å; V165-A175 CarbonylContact O-C 3.42Å; V165-A175 WeakPolarHBondContact O-CA 3.21Å; V165-E176 HydrophobicContact CB-CB 4.48Å; V165-E176 PolarHBondContact N-O 3.31Å; V165-E176 PolarHBondContact O-N 3.13Å; V165-R183 HydrophobicContact CG2-CG 3.85Å; V165-I185 HydrophobicContact CG1-CG2 3.8Å; V165-I185 HydrophobicContact CG2-CG2 3.97Å; V165-I191 HydrophobicContact CB-CD1 4.36Å; V165-I191 HydrophobicContact CB-CG1 4.31Å; V165-I191 HydrophobicContact CG1-CD1 4.01Å; V165-I191 HydrophobicContact CG1-CG1 3.87Å
166L98.9Very high98Very high1 Ų121.5 Ų21.51%0.00510%0.097CC..EExtended strand (participates in β ladder)trans-121.3120.2172.9168.264.9000108.8V126 I129 S154 F155 T168 W173 A175V126-L166 HydrophobicContact CG1-CD1 4.36Å; V126-L166 HydrophobicContact CG1-CD2 4.37Å; I129-L166 HydrophobicContact CB-CD2 3.87Å; I129-L166 HydrophobicContact CD1-CD2 4.41Å; I129-L166 HydrophobicContact CG2-CD2 3.53Å; S154-L166 CarbonylContact C-O 3.4Å; S154-L166 WeakPolarHBondContact CA-O 3.32Å; F155-L166 HydrophobicContact CB-CB 4.29Å; F155-L166 HydrophobicContact CD2-CB 4.39Å; F155-L166 HydrophobicContact CD2-CD2 4.12Å; F155-L166 HydrophobicContact CD2-CG 4.12Å; F155-L166 PolarHBondContact N-O 3.43Å; F155-L166 PolarHBondContact O-N 2.9Å; L166-T168 HydrophobicContact CG-CG2 4.45Å; L166-W173 HydrophobicContact CD1-CB 3.95Å; L166-W173 HydrophobicContact CD1-CD2 4.08Å; L166-W173 HydrophobicContact CD1-CE3 3.61Å; L166-W173 HydrophobicContact CD1-CG 4.25Å; L166-W173 HydrophobicContact CD1-CZ3 4.42Å; L166-A175 HydrophobicContact CB-CB 4.5Å; L166-A175 HydrophobicContact CD1-CB 4.12Å
167E98.6Very high98Very high0 Ų025.3 Ų25.30%011%0.111CC..EExtended strand (participates in β ladder)trans-118.3135.7179.9-68.7-17916200111.2S154 V165 W173 A174 Y189 G190 I191 F220S154-E167 WeakPolarHBondContact OG-CG 3.37Å; S154-E167 PolarHBondContact OG-OE1 3.01Å; V165-E167 HydrophobicContact CG1-CG 4.02Å; E167-W173 CarbonylContact O-C 3.48Å; E167-W173 WeakPolarHBondContact O-CA 3.34Å; E167-W173 WeakPolarHBondContact O-CB 3.36Å; E167-A174 PolarHBondContact N-O 3.32Å; E167-A174 PolarHBondContact O-N 3.05Å; E167-Y189 HydrophobicContact CB-CD1 3.93Å; E167-Y189 HydrophobicContact CB-CE1 4.31Å; E167-Y189 HydrophobicContact CG-CD1 4.26Å; E167-Y189 WeakPolarHBondContact OE1-CA 3.39Å; E167-Y189 WeakPolarHBondContact OE2-CA 3.36Å; E167-Y189 WeakPolarHBondContact OE2-CB 3.27Å; E167-G190 VanDerWaalsContact CD-N 3.27Å; E167-G190 PolarHBondContact OE1-N 3.11Å; E167-G190 PolarHBondContact OE2-N 3.17Å; E167-I191 HydrophobicContact CB-CD1 4.01Å; E167-I191 HydrophobicContact CG-CD1 3.92Å; E167-I191 HydrophobicContact CG-CG1 4.11Å; E167-I191 PolarHBondContact OE2-N 2.95Å; E167-F220 HydrophobicContact CB-CD1 4.26Å; E167-F220 HydrophobicContact CB-CE1 3.52Å; E167-F220 HydrophobicContact CB-CZ 4.18Å
168T98.1Very high97.9Very high0 Ų025.9 Ų25.90%012%0.115CC..EExtended strand (participates in β ladder)trans-119.8146.3-172.268.10000111.7L133 Q138 H152 N153 F155 L166 Y172 W173 Y189L133-T168 HydrophobicContact CD2-CG2 3.8Å; Q138-T168 PolarHBondContact NE2-OG1 3.37Å; Q138-T168 PolarHBondContact OE1-OG1 2.59Å; H152-T168 WeakPolarHBondContact CB-O 3.44Å; N153-T168 PolarHBondContact N-OG1 3.23Å; N153-T168 PolarHBondContact O-N 2.88Å; N153-T168 PolarHBondContact O-OG1 2.91Å; F155-T168 HydrophobicContact CE2-CG2 4Å; L166-T168 HydrophobicContact CG-CG2 4.45Å; T168-Y172 CarbonylContact C-O 3.21Å; T168-Y172 WeakPolarHBondContact CA-O 3.48Å; T168-W173 HydrophobicContact CG2-CB 4.14Å; T168-Y189 WeakPolarHBondContact O-CE1 3.36Å; T168-Y189 PolarHBondContact O-OH 2.73Å; T168-Y189 VanDerWaalsContact O-OH 3.12Å
169S96.3Very high97.8Very high0 Ų031.3 Ų31.30%014%0.14CC..EExtended strand (participates in β ladder)trans-143.796.9176.9-158.90000109.1E98 K171 Y172 Y189 Y224E98-S169 WeakPolarHBondContact CB-OG 3.28Å; S169-K171 PolarHBondContact O-N 3.4Å; S169-Y172 PolarHBondContact N-O 2.78Å; S169-Y172 WeakPolarHBondContact O-CB 3.27Å; S169-Y172 PolarHBondContact O-N 3.19Å; S169-Y189 PolarHBondContact OG-OH 3.46Å; S169-Y224 VanDerWaalsContact OG-CD1 3.3Å; S169-Y224 WeakPolarHBondContact OG-CD1 3.22Å
170G93.3Very high97.7Very high16 Ų1637.3 Ų37.317%0.16517%0.168CC..THydrogen-bonded Turntrans58.4-127.2-164.200000109.5Q138 H152Q138-G170 PolarHBondContact NE2-O 3.26Å; H152-G170 PolarHBondContact CE1-N 3.17Å; H152-G170 PolarHBondContact ND1-N 3.46Å; H152-G170 WeakPolarHBondContact NE2-CA 3.46Å; H152-G170 PolarHBondContact NE2-N 2.9Å
171K93.6Very high97.7Very high112 Ų11236.2 Ų36.249%0.48717%0.169SC..THydrogen-bonded Turntrans-81.7-11.1173.968.3177.5-177.1176.50114.8S169 H199S169-K171 PolarHBondContact O-N 3.4Å; K171-H199 PolarHBondContact O-CD2 3.13Å; K171-H199 VanDerWaalsContact O-CD2 3.3Å
172Y97.8Very high97.7Very high25 Ų2530.7 Ų30.710%0.09814%0.144CC..EExtended strand (participates in β ladder)trans-85.5151.1-177.2-56.3-73.9000110.3T168 S169 H199 M202 Y205T168-Y172 CarbonylContact C-O 3.21Å; T168-Y172 WeakPolarHBondContact CA-O 3.48Å; S169-Y172 PolarHBondContact N-O 2.78Å; S169-Y172 WeakPolarHBondContact O-CB 3.27Å; S169-Y172 PolarHBondContact O-N 3.19Å; Y172-H199 HydrophobicContact CD1-CB 4.49Å; Y172-H199 AromaticContact CD1-CE1 3.82Å; Y172-H199 AromaticContact CD1-CG 3.91Å; Y172-H199 AromaticContact CD1-ND1 3.5Å; Y172-H199 AromaticContact CE1-CE1 3.82Å; Y172-H199 AromaticContact CE1-ND1 3.88Å; Y172-M202 HydrophobicContact CD1-CB 4.14Å; Y172-Y205 AromaticContact CD2-CD1 3.57Å; Y172-Y205 HydrophobicContact CD2-CD1 3.57Å; Y172-Y205 AromaticContact CD2-CE1 3.8Å; Y172-Y205 HydrophobicContact CD2-CE1 3.8Å; Y172-Y205 HydrophobicContact CD2-CG 4.11Å; Y172-Y205 HydrophobicContact CE1-CD1 4.45Å; Y172-Y205 HydrophobicContact CE1-CG 4.07Å; Y172-Y205 AromaticContact CE2-CD1 3.14Å; Y172-Y205 HydrophobicContact CE2-CD1 3.14Å; Y172-Y205 AromaticContact CE2-CD2 3.7Å; Y172-Y205 HydrophobicContact CE2-CD2 3.7Å; Y172-Y205 AromaticContact CE2-CE1 3.35Å; Y172-Y205 HydrophobicContact CE2-CE1 3.35Å; Y172-Y205 AromaticContact CE2-CE2 3.88Å; Y172-Y205 HydrophobicContact CE2-CE2 3.88Å; Y172-Y205 AromaticContact CE2-CG 3.3Å; Y172-Y205 HydrophobicContact CE2-CG 3.3Å; Y172-Y205 AromaticContact CE2-CZ 3.7Å; Y172-Y205 HydrophobicContact CG-CD1 4.38Å; Y172-Y205 VanDerWaalsContact CZ-CB 3.44Å; Y172-Y205 AromaticContact CZ-CD1 3.65Å; Y172-Y205 AromaticContact CZ-CD2 3.58Å; Y172-Y205 AromaticContact CZ-CG 3.26Å; Y172-Y205 WeakPolarHBondContact OH-CB 3.44Å; Y172-Y205 WeakPolarHBondContact OH-CD2 3.49Å; Y172-Y205 VanDerWaalsContact OH-CG 3.24Å
173W98.6Very high97.6Very high25 Ų2531.1 Ų31.110%0.09515%0.145CC..EExtended strand (participates in β ladder)trans-156.8156.2-177.559-94.7000111.7A130 L133 L166 E167 T168 A175 K197 H199 M202A130-W173 HydrophobicContact CB-CD2 4.22Å; A130-W173 HydrophobicContact CB-CH2 4.21Å; A130-W173 HydrophobicContact CB-CZ2 3.54Å; L133-W173 HydrophobicContact CD2-CB 4.44Å; L166-W173 HydrophobicContact CD1-CB 3.95Å; L166-W173 HydrophobicContact CD1-CD2 4.08Å; L166-W173 HydrophobicContact CD1-CE3 3.61Å; L166-W173 HydrophobicContact CD1-CG 4.25Å; L166-W173 HydrophobicContact CD1-CZ3 4.42Å; E167-W173 CarbonylContact O-C 3.48Å; E167-W173 WeakPolarHBondContact O-CA 3.34Å; E167-W173 WeakPolarHBondContact O-CB 3.36Å; T168-W173 HydrophobicContact CG2-CB 4.14Å; W173-A175 HydrophobicContact CE3-CB 4.41Å; W173-A175 HydrophobicContact CZ3-CB 4.18Å; W173-K197 HydrophobicContact CH2-CB 3.87Å; W173-K197 HydrophobicContact CZ3-CB 3.63Å; W173-H199 HydrophobicContact CD2-CB 4.27Å; W173-H199 HydrophobicContact CG-CB 4.09Å; W173-H199 AromaticContact NE1-CD2 3.89Å; W173-H199 PolarHBondContact O-N 3.33Å; W173-M202 VanDerWaalsContact O-SD 3.38Å
174A98.8Very high97.5Very high0 Ų031.3 Ų31.30%015%0.146CC..EExtended strand (participates in β ladder)trans-132149.3169.600000109E167 I191 I195 K197 M202 F220E167-A174 PolarHBondContact N-O 3.32Å; E167-A174 PolarHBondContact O-N 3.05Å; A174-I191 HydrophobicContact CB-CD1 4.25Å; A174-I191 HydrophobicContact CB-CG2 4.22Å; A174-I191 WeakPolarHBondContact O-CD1 3.34Å; A174-I195 HydrophobicContact CB-CD1 4.42Å; A174-I195 HydrophobicContact CB-CG2 4.16Å; A174-K197 CarbonylContact C-O 3.58Å; A174-M202 HydrophobicContact CB-CE 4.36Å; A174-M202 HydrophobicContact CB-SD 4.12Å; A174-F220 HydrophobicContact CB-CB 4.21Å; A174-F220 HydrophobicContact CB-CD1 4.29Å; A174-F220 HydrophobicContact CB-CD2 3.58Å; A174-F220 HydrophobicContact CB-CE2 3.95Å; A174-F220 HydrophobicContact CB-CG 3.76Å; A174-F220 HydrophobicContact CB-CZ 4.46Å
175A98.9Very high97.3Very high0 Ų031.1 Ų31.10%015%0.146CC..EExtended strand (participates in β ladder)trans-133.6138.4176.200000111.9V126 W164 V165 L166 W173 D196 K197V126-A175 HydrophobicContact CG1-CB 3.92Å; W164-A175 HydrophobicContact CE3-CB 4Å; W164-A175 HydrophobicContact CZ3-CB 4.22Å; V165-A175 CarbonylContact O-C 3.42Å; V165-A175 WeakPolarHBondContact O-CA 3.21Å; L166-A175 HydrophobicContact CB-CB 4.5Å; L166-A175 HydrophobicContact CD1-CB 4.12Å; W173-A175 HydrophobicContact CE3-CB 4.41Å; W173-A175 HydrophobicContact CZ3-CB 4.18Å; A175-D196 PolarHBondContact O-N 2.79Å; A175-K197 HydrophobicContact CB-CB 4.2Å; A175-K197 PolarHBondContact N-O 2.69Å; A175-K197 PolarHBondContact O-N 2.8Å
176E98.8Very high97Very high27 Ų2731.2 Ų31.213%0.12615%0.146CC..EExtended strand (participates in β ladder)trans-118.3129179.4-175.7-165.3160.900109.1W164 V165 R183 I191 K194W164-E176 WeakPolarHBondContact CA-O 3.31Å; V165-E176 HydrophobicContact CB-CB 4.48Å; V165-E176 PolarHBondContact N-O 3.31Å; V165-E176 PolarHBondContact O-N 3.13Å; E176-R183 IonicContact OE2-NE 3.46Å; E176-R183 IonicContact OE2-NH2 3.36Å; E176-R183 PolarHBondContact OE2-NH2 2.82Å; E176-I191 HydrophobicContact CB-CD1 4.24Å; E176-I191 HydrophobicContact CB-CG1 4.05Å; E176-I191 HydrophobicContact CB-CG2 4.4Å; E176-K194 HydrophobicContact CG-CD 4Å; E176-K194 HydrophobicContact CG-CG 4.27Å
177R98.7Very high96.6Very high80 Ų8031.5 Ų31.530%0.30215%0.148SC..EExtended strand (participates in β ladder)trans-88.9137.5176.9-169.9177.5177.5-155.8-14.1111.1E162 W164 E179 K194 D196E162-R177 IonicContact OE2-CZ 2.67Å; E162-R177 IonicContact OE2-NE 3.14Å; E162-R177 PolarHBondContact OE2-NE 3.36Å; E162-R177 IonicContact OE2-NH2 2.7Å; E162-R177 PolarHBondContact OE2-NH2 3.14Å; W164-R177 HydrophobicContact CD2-CB 4.07Å; W164-R177 HydrophobicContact CD2-CG 4.19Å; W164-R177 HydrophobicContact CE3-CB 3.96Å; W164-R177 HydrophobicContact CH2-CB 3.75Å; W164-R177 HydrophobicContact CH2-CG 4.08Å; W164-R177 HydrophobicContact CZ2-CB 3.84Å; W164-R177 HydrophobicContact CZ2-CG 3.65Å; W164-R177 HydrophobicContact CZ3-CB 3.8Å; R177-E179 HydrophobicContact CG-CG 4.16Å; R177-E179 IonicContact CZ-OE1 3.82Å; R177-E179 IonicContact NE-OE1 2.8Å; R177-E179 IonicContact NH1-OE1 3.43Å; R177-E179 PolarHBondContact NH1-OE1 2.84Å; R177-E179 IonicContact NH2-OE1 2.73Å; R177-E179 PolarHBondContact NH2-OE1 3.14Å; R177-K194 PolarHBondContact O-NZ 2.94Å; R177-D196 HydrophobicContact CB-CB 4.16Å; R177-D196 PolarHBondContact N-OD2 3.25Å
178V98.3Very high96.1Very high13 Ų1333.2 Ų33.28%0.07916%0.156CC..EExtended strand (participates in β ladder)trans-123.2111.7177-1760000108.5L12 A163 R183L12-V178 HydrophobicContact CD1-CG1 4.25Å; A163-V178 HydrophobicContact CB-CB 4.26Å; A163-V178 PolarHBondContact N-O 2.8Å; A163-V178 PolarHBondContact O-N 2.65Å; V178-R183 HydrophobicContact CG1-CB 4.3Å; V178-R183 HydrophobicContact CG2-CB 4.17Å; V178-R183 HydrophobicContact CG2-CG 4.11Å
179E96.8Very high95.9Very high116 Ų11633.7 Ų33.754%0.54216%0.158SC..  trans-98.1-21.3-174.5-62.5-175.5111.600113.2R177R177-E179 HydrophobicContact CG-CG 4.16Å; R177-E179 IonicContact CZ-OE1 3.82Å; R177-E179 IonicContact NE-OE1 2.8Å; R177-E179 IonicContact NH1-OE1 3.43Å; R177-E179 PolarHBondContact NH1-OE1 2.84Å; R177-E179 IonicContact NH2-OE1 2.73Å; R177-E179 PolarHBondContact NH2-OE1 3.14Å
180E96.8Very high95.7Very high138 Ų13834.4 Ų34.465%0.64517%0.165SC*.SBendtrans-154.9169.6-178.661.3175.8-158.700111.1P13P13-E180 WeakPolarHBondContact O-CA 3.43Å; P13-E180 VanDerWaalsContact O-CB 3.26Å; P13-E180 WeakPolarHBondContact O-CB 3.29Å
181G97.3Very high95.9Very high18 Ų1833.7 Ų33.719%0.18616%0.157CC..EExtended strand (participates in β ladder)trans81.4-13817500000112.5L12 S15L12-G181 PolarHBondContact N-O 3.01Å; S15-G181 WeakPolarHBondContact CB-O 3.43Å
182Y97.5Very high96Very high53 Ų5331.3 Ų31.321%0.20815%0.152CC..EExtended strand (participates in β ladder)trans-141152.3-179.358.2-91.4000111.1V10 S15 K243 L246 E247 N250V10-Y182 CarbonylContact O-C 3.53Å; V10-Y182 VanDerWaalsContact O-CA 3.23Å; V10-Y182 WeakPolarHBondContact O-CA 3.39Å; V10-Y182 WeakPolarHBondContact O-CB 3.44Å; S15-Y182 WeakPolarHBondContact OG-CD1 3.48Å; Y182-K243 HydrophobicContact CE2-CG 4.24Å; Y182-L246 HydrophobicContact CD2-CB 3.6Å; Y182-L246 HydrophobicContact CD2-CD1 3.77Å; Y182-L246 HydrophobicContact CD2-CG 4.33Å; Y182-L246 HydrophobicContact CE2-CB 3.95Å; Y182-L246 HydrophobicContact CG-CB 4.04Å; Y182-L246 HydrophobicContact CG-CD1 4.31Å; Y182-E247 HydrophobicContact CE2-CB 4.48Å; Y182-E247 VanDerWaalsContact OH-CB 3.28Å; Y182-E247 WeakPolarHBondContact OH-CB 3.5Å; Y182-E247 WeakPolarHBondContact OH-CG 3.35Å; Y182-N250 HydrophobicContact CE1-CB 4Å
183R97Very high96Very high24 Ų2432.9 Ų32.99%0.09117%0.165CC..EExtended strand (participates in β ladder)trans-145.2143.3177.7-173.766.6163.5111.2-13.3109.5F9 V10 L156 V165 E176 V178 G190 Y239F9-R183 CarbonylContact C-O 3.5Å; F9-R183 WeakPolarHBondContact CA-O 3.32Å; V10-R183 HydrophobicContact CG1-CB 3.87Å; V10-R183 PolarHBondContact N-O 3.26Å; V10-R183 PolarHBondContact O-N 3.31Å; L156-R183 HydrophobicContact CD1-CG 4.4Å; V165-R183 HydrophobicContact CG2-CG 3.85Å; E176-R183 IonicContact OE2-NE 3.46Å; E176-R183 IonicContact OE2-NH2 3.36Å; E176-R183 PolarHBondContact OE2-NH2 2.82Å; V178-R183 HydrophobicContact CG1-CB 4.3Å; V178-R183 HydrophobicContact CG2-CB 4.17Å; V178-R183 HydrophobicContact CG2-CG 4.11Å; R183-G190 PolarHBondContact NH2-O 2.79Å; R183-Y239 PolarHBondContact NH1-OH 3.49Å; R183-Y239 VanDerWaalsContact NH1-OH 3.12Å
184N96.3Very high95.9Very high3 Ų336.2 Ų36.22%0.01618%0.18CC..EExtended strand (participates in β ladder)trans-127.7158166.467.7-51.9000110.7T8 F9 Y239 L246T8-N184 CarbonylContact O-C 3.58Å; T8-N184 WeakPolarHBondContact O-CA 3.16Å; T8-N184 WeakPolarHBondContact O-CB 3.4Å; F9-N184 HydrophobicContact CD1-CB 3.48Å; F9-N184 VanDerWaalsContact CD1-CB 3.48Å; F9-N184 HydrophobicContact CE1-CB 3.81Å; F9-N184 HydrophobicContact CG-CB 4.27Å; N184-Y239 WeakPolarHBondContact ND2-CD2 3.17Å; N184-Y239 PolarHBondContact ND2-O 3.22Å; N184-Y239 WeakPolarHBondContact O-CE2 3.22Å; N184-L246 HydrophobicContact CB-CD1 4.16Å
185I94.8Very high95.9Very high3 Ų337.9 Ų37.92%0.01519%0.188CC..EExtended strand (participates in β ladder)trans-127.6154.8166.961.8168.5000109T8 E92 L156 V165T8-I185 PolarHBondContact N-O 3.26Å; T8-I185 VanDerWaalsContact N-O 3.14Å; T8-I185 PolarHBondContact O-N 2.71Å; E92-I185 HydrophobicContact CB-CD1 4.45Å; E92-I185 HydrophobicContact CG-CD1 3.79Å; E92-I185 HydrophobicContact CG-CG1 3.89Å; L156-I185 HydrophobicContact CB-CD1 3.73Å; L156-I185 HydrophobicContact CB-CG1 4.03Å; V165-I185 HydrophobicContact CG1-CG2 3.8Å; V165-I185 HydrophobicContact CG2-CG2 3.97Å
186S91.5Very high95.9Very high1 Ų141.5 Ų41.51%0.00721%0.208CC..  trans-143.3-165.6175.2-162.50000107.3D7 Q188D7-S186 VanDerWaalsContact OD1-CB 3.3Å; D7-S186 WeakPolarHBondContact OD1-CB 3.48Å; D7-S186 PolarHBondContact OD1-OG 2.81Å; S186-Q188 PolarHBondContact O-N 3.29Å
187N90.6Very high95.9Very high8 Ų842.2 Ų42.24%0.04321%0.21CC..SBendtrans-82.446.8-172.3-62.368.8000114.6S5 C6 A93 W95 A235S5-N187 VanDerWaalsContact C-OD1 3.3Å; S5-N187 WeakPolarHBondContact CA-OD1 3.34Å; S5-N187 WeakPolarHBondContact CB-OD1 3.36Å; S5-N187 WeakPolarHBondContact OG-CB 3.43Å; S5-N187 PolarHBondContact OG-OD1 2.97Å; C6-N187 PolarHBondContact N-OD1 3.17Å; C6-N187 PolarHBondContact O-OD1 3.24Å; A93-N187 WeakPolarHBondContact CB-ND2 3.28Å; A93-N187 PolarHBondContact N-ND2 2.96Å; A93-N187 VanDerWaalsContact O-CA 3.22Å; A93-N187 WeakPolarHBondContact O-CA 3.49Å; A93-N187 WeakPolarHBondContact O-CB 3.2Å; A93-N187 VanDerWaalsContact O-CG 3.26Å; A93-N187 PolarHBondContact O-ND2 3.37Å; W95-N187 HydrophobicContact CZ3-CB 4.27Å; N187-A235 HydrophobicContact CB-CB 4.09Å
188Q89.2Confident95.9Very high35 Ų3541.5 Ų41.516%0.16421%0.21CC..SBendtrans-147.5157.6174.162.6177.69.300110S186 G190 A235S186-Q188 PolarHBondContact O-N 3.29Å; Q188-G190 PolarHBondContact O-N 2.91Å; Q188-A235 HydrophobicContact CB-CB 4.28Å; Q188-A235 HydrophobicContact CG-CB 4.39Å
189Y93.1Very high95.9Very high11 Ų1141.7 Ų41.74%0.04321%0.21CC..  trans-68.3131.9170-61.6-59.5000110.8V94 E167 T168 S169 F220 A221V94-Y189 HydrophobicContact CB-CD1 4.33Å; V94-Y189 HydrophobicContact CB-CE1 4.04Å; V94-Y189 HydrophobicContact CG2-CD1 4.15Å; V94-Y189 HydrophobicContact CG2-CE1 3.51Å; E167-Y189 HydrophobicContact CB-CD1 3.93Å; E167-Y189 HydrophobicContact CB-CE1 4.31Å; E167-Y189 HydrophobicContact CG-CD1 4.26Å; E167-Y189 WeakPolarHBondContact OE1-CA 3.39Å; E167-Y189 WeakPolarHBondContact OE2-CA 3.36Å; E167-Y189 WeakPolarHBondContact OE2-CB 3.27Å; T168-Y189 WeakPolarHBondContact O-CE1 3.36Å; T168-Y189 PolarHBondContact O-OH 2.73Å; T168-Y189 VanDerWaalsContact O-OH 3.12Å; S169-Y189 PolarHBondContact OG-OH 3.46Å; Y189-F220 HydrophobicContact CD1-CD1 4.35Å; Y189-F220 AromaticContact CD1-CE1 3.55Å; Y189-F220 HydrophobicContact CD1-CE1 3.55Å; Y189-F220 HydrophobicContact CD1-CZ 4.39Å; Y189-F220 AromaticContact CE1-CE1 3.85Å; Y189-F220 HydrophobicContact CE1-CE1 3.85Å; Y189-F220 HydrophobicContact CE1-CZ 4.25Å; Y189-F220 HydrophobicContact CG-CE1 4.04Å; Y189-A221 WeakPolarHBondContact O-CB 3.35Å
190G92.2Very high95.9Very high15 Ų1541.7 Ų41.716%0.15522%0.22CC..  trans-123-9.8-177.400000114.1E167 R183 Q188E167-G190 VanDerWaalsContact CD-N 3.27Å; E167-G190 PolarHBondContact OE1-N 3.11Å; E167-G190 PolarHBondContact OE2-N 3.17Å; R183-G190 PolarHBondContact NH2-O 2.79Å; Q188-G190 PolarHBondContact O-N 2.91Å
191I96.9Very high96Very high0 Ų036.3 Ų36.30%020%0.202CC..  trans-76.3124.3174.1-63177000108.9V165 E167 A174 E176 I195 F220 A221V165-I191 HydrophobicContact CB-CD1 4.36Å; V165-I191 HydrophobicContact CB-CG1 4.31Å; V165-I191 HydrophobicContact CG1-CD1 4.01Å; V165-I191 HydrophobicContact CG1-CG1 3.87Å; E167-I191 HydrophobicContact CB-CD1 4.01Å; E167-I191 HydrophobicContact CG-CD1 3.92Å; E167-I191 HydrophobicContact CG-CG1 4.11Å; E167-I191 PolarHBondContact OE2-N 2.95Å; A174-I191 HydrophobicContact CB-CD1 4.25Å; A174-I191 HydrophobicContact CB-CG2 4.22Å; A174-I191 WeakPolarHBondContact O-CD1 3.34Å; E176-I191 HydrophobicContact CB-CD1 4.24Å; E176-I191 HydrophobicContact CB-CG1 4.05Å; E176-I191 HydrophobicContact CB-CG2 4.4Å; I191-I195 HydrophobicContact CG2-CG1 3.85Å; I191-F220 HydrophobicContact CB-CB 4.36Å; I191-F220 HydrophobicContact CB-CD1 4.2Å; I191-F220 HydrophobicContact CG2-CB 4.14Å; I191-F220 WeakPolarHBondContact O-CB 3.29Å; I191-A221 VanDerWaalsContact O-CB 3.22Å; I191-A221 WeakPolarHBondContact O-CB 3.49Å; I191-A221 PolarHBondContact O-N 2.83Å
192T96.4Very high96Very high63 Ų6335.4 Ų35.439%0.38719%0.193SC..  trans-104.4-115-17658.70000111N219 F220T192-N219 WeakPolarHBondContact CB-ND2 3.46Å; T192-N219 WeakPolarHBondContact O-CA 3.22Å; T192-F220 PolarHBondContact O-N 2.88Å
193T97.3Very high96Very high58 Ų5837 Ų3736%0.35620%0.199SC..SBendtrans-94.3-23.1-177.757.10000112.6I195 E217 N219T193-I195 PolarHBondContact O-N 3.08Å; T193-E217 HydrophobicContact CG2-CG 3.77Å; T193-N219 HydrophobicContact CG2-CB 3.94Å
194K97.3Very high96.1Very high95 Ų9540.7 Ų40.741%0.41322%0.223SC..  trans-75.1107.1169.7-172.6-171.6177.7-165.20109.2E176 R177 D196E176-K194 HydrophobicContact CG-CD 4Å; E176-K194 HydrophobicContact CG-CG 4.27Å; R177-K194 PolarHBondContact O-NZ 2.94Å; K194-D196 WeakPolarHBondContact CE-OD2 3.26Å
195I98.6Very high96.2Very high34 Ų3442.3 Ų42.317%0.17423%0.23CC..  trans-132.4114179.3-59.6175.9000107.4A174 I191 T193 K197 E198 M202 F218 F220A174-I195 HydrophobicContact CB-CD1 4.42Å; A174-I195 HydrophobicContact CB-CG2 4.16Å; I191-I195 HydrophobicContact CG2-CG1 3.85Å; T193-I195 PolarHBondContact O-N 3.08Å; I195-K197 VanDerWaalsContact CG2-O 3.27Å; I195-K197 WeakPolarHBondContact CG2-O 3.16Å; I195-E198 HydrophobicContact CG2-CB 3.85Å; I195-E198 HydrophobicContact CG2-CG 4.4Å; I195-M202 HydrophobicContact CD1-CE 4.43Å; I195-F218 HydrophobicContact CD1-CD1 3.82Å; I195-F218 HydrophobicContact CD1-CE1 4.2Å; I195-F220 HydrophobicContact CD1-CB 4.18Å
196D98.8Very high96.3Very high77 Ų7742.1 Ų42.141%0.41223%0.229SC..SBendtrans-91.9-32.9-177.1-66.4-79.5000111.6W164 A175 R177 K194W164-D196 HydrophobicContact CH2-CB 4.01Å; W164-D196 HydrophobicContact CZ3-CB 3.76Å; A175-D196 PolarHBondContact O-N 2.79Å; R177-D196 HydrophobicContact CB-CB 4.16Å; R177-D196 PolarHBondContact N-OD2 3.25Å; K194-D196 WeakPolarHBondContact CE-OD2 3.26Å
197K98.8Very high96.6Very high42 Ų4246.2 Ų46.218%0.18325%0.248CC..EExtended strand (participates in β ladder)trans-136.2146.2170.2-62.8-177.8173.3-176.40110.3E123 V126 D127 W164 W173 A174 A175 I195E123-K197 WeakPolarHBondContact OE1-CE 3.41Å; E123-K197 IonicContact OE1-NZ 3.81Å; E123-K197 PolarHBondContact OE1-NZ 2.81Å; V126-K197 HydrophobicContact CG1-CD 4.41Å; D127-K197 VanDerWaalsContact CG-NZ 3.28Å; D127-K197 IonicContact OD1-NZ 2.82Å; D127-K197 PolarHBondContact OD1-NZ 3.28Å; D127-K197 IonicContact OD2-NZ 3.9Å; D127-K197 PolarHBondContact OD2-NZ 2.88Å; D127-K197 VanDerWaalsContact OD2-NZ 3.1Å; W164-K197 HydrophobicContact CH2-CD 4.19Å; W164-K197 HydrophobicContact CH2-CG 4.19Å; W164-K197 HydrophobicContact CZ3-CD 4.24Å; W164-K197 HydrophobicContact CZ3-CG 4.12Å; W173-K197 HydrophobicContact CH2-CB 3.87Å; W173-K197 HydrophobicContact CZ3-CB 3.63Å; A174-K197 CarbonylContact C-O 3.58Å; A175-K197 HydrophobicContact CB-CB 4.2Å; A175-K197 PolarHBondContact N-O 2.69Å; A175-K197 PolarHBondContact O-N 2.8Å; I195-K197 VanDerWaalsContact CG2-O 3.27Å; I195-K197 WeakPolarHBondContact CG2-O 3.16Å
198E98.6Very high96.9Very high64 Ų6450 Ų5030%0.29928%0.275SS..EExtended strand (participates in β ladder)trans-148.2156.5176.659.1180-162.200112.5I195 M202 R203I195-E198 HydrophobicContact CG2-CB 3.85Å; I195-E198 HydrophobicContact CG2-CG 4.4Å; E198-M202 HydrophobicContact CB-CE 3.79Å; E198-M202 HydrophobicContact CG-CE 4.46Å; E198-M202 VanDerWaalsContact OE2-CE 3.22Å; E198-M202 WeakPolarHBondContact OE2-CE 3.47Å; E198-R203 IonicContact OE1-CZ 3.55Å; E198-R203 IonicContact OE1-NE 3.9Å; E198-R203 PolarHBondContact OE1-NE 3.47Å; E198-R203 IonicContact OE1-NH2 2.97Å; E198-R203 IonicContact OE2-CZ 3.66Å; E198-R203 IonicContact OE2-NE 3.74Å; E198-R203 PolarHBondContact OE2-NE 2.86Å; E198-R203 IonicContact OE2-NH2 2.69Å; E198-R203 PolarHBondContact OE2-NH2 2.93Å
199H98.5Very high97.3Very high17 Ų1753.3 Ų53.38%0.07929%0.289CS..  trans-65128.7168.6-178.7-68.5000110K171 Y172 W173 G201 M202K171-H199 PolarHBondContact O-CD2 3.13Å; K171-H199 VanDerWaalsContact O-CD2 3.3Å; Y172-H199 HydrophobicContact CD1-CB 4.49Å; Y172-H199 AromaticContact CD1-CE1 3.82Å; Y172-H199 AromaticContact CD1-CG 3.91Å; Y172-H199 AromaticContact CD1-ND1 3.5Å; Y172-H199 AromaticContact CE1-CE1 3.82Å; Y172-H199 AromaticContact CE1-ND1 3.88Å; W173-H199 HydrophobicContact CD2-CB 4.27Å; W173-H199 HydrophobicContact CG-CB 4.09Å; W173-H199 AromaticContact NE1-CD2 3.89Å; W173-H199 PolarHBondContact O-N 3.33Å; H199-G201 VanDerWaalsContact C-N 3.27Å; H199-G201 PolarHBondContact ND1-N 3.13Å; H199-G201 PolarHBondContact O-N 3.32Å; H199-G201 VanDerWaalsContact O-N 3.12Å; H199-M202 HydrophobicContact CB-CB 4.21Å; H199-M202 WeakPolarHBondContact O-CB 3.44Å; H199-M202 PolarHBondContact O-N 3.12Å
200P97.6Very high97.4Very high116 Ų11655.8 Ų55.875%0.75332%0.318SS*.THydrogen-bonded Turntrans-61.8-31.3-17122.6-34.1000114
201G97.8Very high97.6Very high25 Ų2557.5 Ų57.526%0.25832%0.32SS..THydrogen-bonded Turntrans-85.9-3176.200000116.2H199 R203 Y205H199-G201 VanDerWaalsContact C-N 3.27Å; H199-G201 PolarHBondContact ND1-N 3.13Å; H199-G201 PolarHBondContact O-N 3.32Å; H199-G201 VanDerWaalsContact O-N 3.12Å; G201-R203 PolarHBondContact O-N 3.12Å; G201-Y205 WeakPolarHBondContact O-CB 3.49Å; G201-Y205 PolarHBondContact O-N 2.83Å
202M97.4Very high97.6Very high0 Ų059.1 Ų59.10%033%0.326CS..Hα-helixtrans-60-52.3-169.8-179.1-17768.800112.3Y172 W173 A174 I195 E198 H199 V204 Y205 A206 F218 F220 Y224Y172-M202 HydrophobicContact CD1-CB 4.14Å; W173-M202 VanDerWaalsContact O-SD 3.38Å; A174-M202 HydrophobicContact CB-CE 4.36Å; A174-M202 HydrophobicContact CB-SD 4.12Å; I195-M202 HydrophobicContact CD1-CE 4.43Å; E198-M202 HydrophobicContact CB-CE 3.79Å; E198-M202 HydrophobicContact CG-CE 4.46Å; E198-M202 VanDerWaalsContact OE2-CE 3.22Å; E198-M202 WeakPolarHBondContact OE2-CE 3.47Å; H199-M202 HydrophobicContact CB-CB 4.21Å; H199-M202 WeakPolarHBondContact O-CB 3.44Å; H199-M202 PolarHBondContact O-N 3.12Å; M202-V204 PolarHBondContact O-N 3.04Å; M202-Y205 WeakPolarHBondContact O-CB 3.26Å; M202-Y205 PolarHBondContact O-N 3.08Å; M202-A206 PolarHBondContact O-N 3.35Å; M202-F218 HydrophobicContact CE-CD1 4.25Å; M202-F218 HydrophobicContact CE-CE1 3.49Å; M202-F218 VanDerWaalsContact CE-CE1 3.49Å; M202-F218 HydrophobicContact CE-CZ 3.94Å; M202-F218 HydrophobicContact SD-CE1 4.4Å; M202-F220 HydrophobicContact CE-CD2 4.24Å; M202-F220 HydrophobicContact SD-CD2 3.44Å; M202-F220 WeakPolarHBondContact SD-CD2 3.48Å; M202-F220 HydrophobicContact SD-CE2 3.51Å; M202-F220 VanDerWaalsContact SD-CE2 3.51Å; M202-Y224 HydrophobicContact CG-CE2 3.57Å; M202-Y224 WeakPolarHBondContact CG-OH 3.04Å; M202-Y224 PolarHBondContact O-OH 3.44Å; M202-Y224 HydrophobicContact SD-CE2 4.03Å
203R98.2Very high97.5Very high86 Ų8660.9 Ų60.933%0.32533%0.333SS..Hα-helixtrans-65.8-43.5-176.2-61.2-172.7-173.4-149.3-3.2112.6E198 G201 Y205 A206 Q207 W212 F218E198-R203 IonicContact OE1-CZ 3.55Å; E198-R203 IonicContact OE1-NE 3.9Å; E198-R203 PolarHBondContact OE1-NE 3.47Å; E198-R203 IonicContact OE1-NH2 2.97Å; E198-R203 IonicContact OE2-CZ 3.66Å; E198-R203 IonicContact OE2-NE 3.74Å; E198-R203 PolarHBondContact OE2-NE 2.86Å; E198-R203 IonicContact OE2-NH2 2.69Å; E198-R203 PolarHBondContact OE2-NH2 2.93Å; G201-R203 PolarHBondContact O-N 3.12Å; R203-Y205 VanDerWaalsContact C-N 3.29Å; R203-Y205 PolarHBondContact O-N 3.06Å; R203-A206 PolarHBondContact O-N 3.45Å; R203-Q207 WeakPolarHBondContact O-CG 3.4Å; R203-Q207 PolarHBondContact O-N 2.82Å; R203-W212 HydrophobicContact CB-CE3 4.26Å; R203-W212 HydrophobicContact CB-CZ3 3.85Å; R203-W212 HydrophobicContact CG-CZ3 4.41Å; R203-F218 HydrophobicContact CB-CD2 4.49Å; R203-F218 HydrophobicContact CB-CE2 4.34Å; R203-F218 HydrophobicContact CG-CD2 3.93Å; R203-F218 HydrophobicContact CG-CE2 3.93Å; R203-F218 HydrophobicContact CG-CG 4.24Å; R203-F218 HydrophobicContact CG-CZ 4.25Å
204V98.2Very high97.4Very high101 Ų10159.5 Ų59.561%0.61233%0.33SS*.Hα-helixtrans-61.7-41.3177.2176.60000110.4M202 Q207 S208M202-V204 PolarHBondContact O-N 3.04Å; V204-Q207 PolarHBondContact O-N 3.42Å; V204-S208 PolarHBondContact O-N 3.23Å
205Y97.8Very high97.3Very high37 Ų3763.8 Ų63.815%0.14535%0.349CS..Hα-helixtrans-62.6-49.5175.6-179.4-107.3000111.9E98 Y172 G201 M202 R203 Q207 S208 K209 W211E98-Y205 VanDerWaalsContact CD-OH 3.28Å; E98-Y205 PolarHBondContact OE1-OH 2.97Å; E98-Y205 VanDerWaalsContact OE2-CE1 3.3Å; E98-Y205 WeakPolarHBondContact OE2-CE1 3.4Å; E98-Y205 PolarHBondContact OE2-OH 3.49Å; Y172-Y205 AromaticContact CD2-CD1 3.57Å; Y172-Y205 HydrophobicContact CD2-CD1 3.57Å; Y172-Y205 AromaticContact CD2-CE1 3.8Å; Y172-Y205 HydrophobicContact CD2-CE1 3.8Å; Y172-Y205 HydrophobicContact CD2-CG 4.11Å; Y172-Y205 HydrophobicContact CE1-CD1 4.45Å; Y172-Y205 HydrophobicContact CE1-CG 4.07Å; Y172-Y205 AromaticContact CE2-CD1 3.14Å; Y172-Y205 HydrophobicContact CE2-CD1 3.14Å; Y172-Y205 AromaticContact CE2-CD2 3.7Å; Y172-Y205 HydrophobicContact CE2-CD2 3.7Å; Y172-Y205 AromaticContact CE2-CE1 3.35Å; Y172-Y205 HydrophobicContact CE2-CE1 3.35Å; Y172-Y205 AromaticContact CE2-CE2 3.88Å; Y172-Y205 HydrophobicContact CE2-CE2 3.88Å; Y172-Y205 AromaticContact CE2-CG 3.3Å; Y172-Y205 HydrophobicContact CE2-CG 3.3Å; Y172-Y205 AromaticContact CE2-CZ 3.7Å; Y172-Y205 HydrophobicContact CG-CD1 4.38Å; Y172-Y205 VanDerWaalsContact CZ-CB 3.44Å; Y172-Y205 AromaticContact CZ-CD1 3.65Å; Y172-Y205 AromaticContact CZ-CD2 3.58Å; Y172-Y205 AromaticContact CZ-CG 3.26Å; Y172-Y205 WeakPolarHBondContact OH-CB 3.44Å; Y172-Y205 WeakPolarHBondContact OH-CD2 3.49Å; Y172-Y205 VanDerWaalsContact OH-CG 3.24Å; G201-Y205 WeakPolarHBondContact O-CB 3.49Å; G201-Y205 PolarHBondContact O-N 2.83Å; M202-Y205 WeakPolarHBondContact O-CB 3.26Å; M202-Y205 PolarHBondContact O-N 3.08Å; R203-Y205 VanDerWaalsContact C-N 3.29Å; R203-Y205 PolarHBondContact O-N 3.06Å; Y205-Q207 VanDerWaalsContact C-N 3.29Å; Y205-Q207 PolarHBondContact O-N 3.16Å; Y205-S208 WeakPolarHBondContact O-CB 3.39Å; Y205-S208 PolarHBondContact O-N 3.46Å; Y205-S208 PolarHBondContact O-OG 3.37Å; Y205-K209 HydrophobicContact CD1-CG 4.42Å; Y205-K209 HydrophobicContact CE1-CG 4.1Å; Y205-K209 HydrophobicContact CE2-CD 4.46Å; Y205-K209 HydrophobicContact CE2-CG 4.25Å; Y205-K209 WeakPolarHBondContact O-CG 3.31Å; Y205-K209 PolarHBondContact O-N 2.99Å; Y205-K209 WeakPolarHBondContact OH-CE 3.4Å; Y205-K209 PolarHBondContact OH-NZ 2.97Å; Y205-W211 HydrophobicContact CD1-CZ3 4.36Å; Y205-W211 HydrophobicContact CE1-CH2 4.08Å; Y205-W211 AromaticContact CE1-CZ3 3.9Å; Y205-W211 HydrophobicContact CE1-CZ3 3.9Å
206A97.5Very high97.2Very high0 Ų065 Ų650%036%0.36CS..Hα-helixtrans-58-39.8177.800000112.6M202 R203 K209 G210 W211 W212 F218 V223 Y224M202-A206 PolarHBondContact O-N 3.35Å; R203-A206 PolarHBondContact O-N 3.45Å; A206-K209 PolarHBondContact O-N 3.42Å; A206-G210 PolarHBondContact O-N 3.48Å; A206-W211 PolarHBondContact O-N 3.02Å; A206-W212 HydrophobicContact CB-CB 4.27Å; A206-W212 PolarHBondContact O-N 2.79Å; A206-F218 HydrophobicContact CB-CE2 4.23Å; A206-V223 HydrophobicContact CB-CG1 3.59Å; A206-Y224 HydrophobicContact CB-CE2 4.32Å
207Q97.6Very high97Very high86 Ų8668.5 Ų68.540%0.40237%0.374SS..Hα-helixtrans-63.2-45.4172.7-70.7-179.97.300111.9R203 V204 Y205 K209 G210 W212R203-Q207 WeakPolarHBondContact O-CG 3.4Å; R203-Q207 PolarHBondContact O-N 2.82Å; V204-Q207 PolarHBondContact O-N 3.42Å; Y205-Q207 VanDerWaalsContact C-N 3.29Å; Y205-Q207 PolarHBondContact O-N 3.16Å; Q207-K209 PolarHBondContact O-N 2.91Å; Q207-G210 PolarHBondContact O-N 3.17Å; Q207-W212 HydrophobicContact CG-CD2 4.26Å; Q207-W212 HydrophobicContact CG-CE3 3.46Å; Q207-W212 VanDerWaalsContact CG-CE3 3.46Å; Q207-W212 HydrophobicContact CG-CZ3 3.98Å; Q207-W212 VanDerWaalsContact NE2-CE3 3.34Å
208S97.7Very high97Very high89 Ų8966.9 Ų66.962%0.62237%0.367SS*.Hα-helixtrans-61.6-27179.978.50000113.1V204 Y205V204-S208 PolarHBondContact O-N 3.23Å; Y205-S208 WeakPolarHBondContact O-CB 3.39Å; Y205-S208 PolarHBondContact O-N 3.46Å; Y205-S208 PolarHBondContact O-OG 3.37Å
209K96.8Very high96.9Very high103 Ų10365.4 Ų65.445%0.44836%0.361SS..THydrogen-bonded Turntrans-86.7-4.3174.8-64.8-66-168.9168.40113.8Y205 A206 Q207 W211Y205-K209 HydrophobicContact CD1-CG 4.42Å; Y205-K209 HydrophobicContact CE1-CG 4.1Å; Y205-K209 HydrophobicContact CE2-CD 4.46Å; Y205-K209 HydrophobicContact CE2-CG 4.25Å; Y205-K209 WeakPolarHBondContact O-CG 3.31Å; Y205-K209 PolarHBondContact O-N 2.99Å; Y205-K209 WeakPolarHBondContact OH-CE 3.4Å; Y205-K209 PolarHBondContact OH-NZ 2.97Å; A206-K209 PolarHBondContact O-N 3.42Å; Q207-K209 PolarHBondContact O-N 2.91Å; K209-W211 HydrophobicContact CB-CD2 3.61Å; K209-W211 VanDerWaalsContact CB-CE2 3.48Å; K209-W211 HydrophobicContact CB-CE3 4.18Å; K209-W211 HydrophobicContact CB-CG 3.86Å; K209-W211 HydrophobicContact CB-CH2 4.48Å; K209-W211 HydrophobicContact CB-CZ2 3.95Å; K209-W211 HydrophobicContact CD-CZ2 4.36Å; K209-W211 HydrophobicContact CG-CD2 4.31Å; K209-W211 HydrophobicContact CG-CE3 4.48Å; K209-W211 HydrophobicContact CG-CH2 4.18Å; K209-W211 HydrophobicContact CG-CZ2 3.98Å; K209-W211 HydrophobicContact CG-CZ3 4.42Å; K209-W211 VanDerWaalsContact O-CD1 3.32Å; K209-W211 PolarHBondContact O-N 2.85Å
210G96.4Very high96.9Very high63 Ų6364.6 Ų64.665%0.64936%0.358SS*.THydrogen-bonded Turntrans69.319.4-174.900000113.8A206 Q207A206-G210 PolarHBondContact O-N 3.48Å; Q207-G210 PolarHBondContact O-N 3.17Å
211W95.7Very high96.7Very high52 Ų5259.7 Ų59.720%0.19733%0.327CS..SBendtrans-83.4-24.4178.7-58.5-14.4000112.8R97 E98 Y205 A206 K209 V223 Y224R97-W211 HydrophobicContact CB-CD2 4.16Å; R97-W211 HydrophobicContact CB-CE3 4.33Å; R97-W211 HydrophobicContact CB-CH2 3.81Å; R97-W211 HydrophobicContact CB-CZ2 3.6Å; R97-W211 HydrophobicContact CB-CZ3 4.17Å; R97-W211 VanDerWaalsContact NH1-CD1 3.3Å; E98-W211 HydrophobicContact CB-CH2 4.28Å; E98-W211 WeakPolarHBondContact OE2-CH2 3.35Å; Y205-W211 HydrophobicContact CD1-CZ3 4.36Å; Y205-W211 HydrophobicContact CE1-CH2 4.08Å; Y205-W211 AromaticContact CE1-CZ3 3.9Å; Y205-W211 HydrophobicContact CE1-CZ3 3.9Å; A206-W211 PolarHBondContact O-N 3.02Å; K209-W211 HydrophobicContact CB-CD2 3.61Å; K209-W211 VanDerWaalsContact CB-CE2 3.48Å; K209-W211 HydrophobicContact CB-CE3 4.18Å; K209-W211 HydrophobicContact CB-CG 3.86Å; K209-W211 HydrophobicContact CB-CH2 4.48Å; K209-W211 HydrophobicContact CB-CZ2 3.95Å; K209-W211 HydrophobicContact CD-CZ2 4.36Å; K209-W211 HydrophobicContact CG-CD2 4.31Å; K209-W211 HydrophobicContact CG-CE3 4.48Å; K209-W211 HydrophobicContact CG-CH2 4.18Å; K209-W211 HydrophobicContact CG-CZ2 3.98Å; K209-W211 HydrophobicContact CG-CZ3 4.42Å; K209-W211 VanDerWaalsContact O-CD1 3.32Å; K209-W211 PolarHBondContact O-N 2.85Å; W211-V223 HydrophobicContact CB-CG1 4.04Å; W211-Y224 HydrophobicContact CE3-CD1 4.14Å; W211-Y224 HydrophobicContact CE3-CE1 4.07Å; W211-Y224 AromaticContact CZ3-CD1 3.8Å; W211-Y224 HydrophobicContact CZ3-CD1 3.8Å; W211-Y224 AromaticContact CZ3-CE1 3.67Å; W211-Y224 HydrophobicContact CZ3-CE1 3.67Å
212W97Very high96.5Very high34 Ų3462.7 Ų62.713%0.12934%0.34CS..  trans-132139.3175.1-178.551.4000109.9R203 A206 Q207 G214 S216 F218 V223R203-W212 HydrophobicContact CB-CE3 4.26Å; R203-W212 HydrophobicContact CB-CZ3 3.85Å; R203-W212 HydrophobicContact CG-CZ3 4.41Å; A206-W212 HydrophobicContact CB-CB 4.27Å; A206-W212 PolarHBondContact O-N 2.79Å; Q207-W212 HydrophobicContact CG-CD2 4.26Å; Q207-W212 HydrophobicContact CG-CE3 3.46Å; Q207-W212 VanDerWaalsContact CG-CE3 3.46Å; Q207-W212 HydrophobicContact CG-CZ3 3.98Å; Q207-W212 VanDerWaalsContact NE2-CE3 3.34Å; W212-G214 VanDerWaalsContact C-N 3.25Å; W212-G214 PolarHBondContact O-N 3.31Å; W212-S216 VanDerWaalsContact CD1-OG 3.29Å; W212-S216 VanDerWaalsContact CE2-O 3.28Å; W212-S216 WeakPolarHBondContact CZ2-O 3.41Å; W212-S216 PolarHBondContact NE1-O 2.95Å; W212-S216 PolarHBondContact NE1-OG 3.34Å; W212-F218 HydrophobicContact CB-CE2 4.36Å; W212-F218 AromaticContact CD2-CD2 3.49Å; W212-F218 HydrophobicContact CD2-CD2 3.49Å; W212-F218 VanDerWaalsContact CD2-CD2 3.49Å; W212-F218 HydrophobicContact CD2-CE2 4.02Å; W212-F218 AromaticContact CE2-CD2 3.8Å; W212-F218 AromaticContact CE3-CD2 3.55Å; W212-F218 HydrophobicContact CE3-CD2 3.55Å; W212-F218 AromaticContact CE3-CE2 3.91Å; W212-F218 HydrophobicContact CE3-CE2 3.91Å; W212-F218 AromaticContact CG-CD2 3.92Å; W212-F218 HydrophobicContact CG-CD2 3.92Å; W212-F218 HydrophobicContact CG-CE2 4.18Å; W212-F218 HydrophobicContact CH2-CD2 4.31Å; W212-F218 HydrophobicContact CZ2-CB 4.21Å; W212-F218 HydrophobicContact CZ2-CD2 4.22Å; W212-F218 AromaticContact CZ3-CD2 3.97Å; W212-F218 HydrophobicContact CZ3-CD2 3.97Å; W212-V223 HydrophobicContact CB-CG1 4.12Å; W212-V223 HydrophobicContact CB-CG2 4.02Å; W212-V223 HydrophobicContact CG-CG2 4.27Å
213D95.1Very high96.4Very high100 Ų10063.1 Ų63.154%0.53534%0.343SS..  trans-79.5-7.9-176.868.7-11000113.8K215 S216D213-K215 PolarHBondContact O-N 3.37Å; D213-K215 PolarHBondContact OD1-N 2.85Å; D213-S216 WeakPolarHBondContact OD1-CB 3.34Å; D213-S216 PolarHBondContact OD1-N 3.32Å; D213-S216 PolarHBondContact OD1-OG 3.44Å; D213-S216 PolarHBondContact OD2-N 3.29Å
214G94.9Very high96.2Very high29 Ų2959 Ų5930%0.29933%0.327SS..SBendtrans73.66.2-17600000114.9W212W212-G214 VanDerWaalsContact C-N 3.25Å; W212-G214 PolarHBondContact O-N 3.31Å
215K94.9Very high95.8Very high185 Ų18555 Ų5580%0.80430%0.304SS*.SBendtrans-122.2-45-175.2-62178.9-177.8176.70112.2D213D213-K215 PolarHBondContact O-N 3.37Å; D213-K215 PolarHBondContact OD1-N 2.85Å
216S95.1Very high95.1Very high59 Ų5957.6 Ų57.641%0.41332%0.316SS..SBendtrans-62.8154.1174.556.70000111W212 D213 F218W212-S216 VanDerWaalsContact CD1-OG 3.29Å; W212-S216 VanDerWaalsContact CE2-O 3.28Å; W212-S216 WeakPolarHBondContact CZ2-O 3.41Å; W212-S216 PolarHBondContact NE1-O 2.95Å; W212-S216 PolarHBondContact NE1-OG 3.34Å; D213-S216 WeakPolarHBondContact OD1-CB 3.34Å; D213-S216 PolarHBondContact OD1-N 3.32Å; D213-S216 PolarHBondContact OD1-OG 3.44Å; D213-S216 PolarHBondContact OD2-N 3.29Å; S216-F218 PolarHBondContact O-N 3.04Å
217E96.4Very high93.1Very high150 Ų15064.7 Ų64.770%0.70135%0.353SS*.PPolyproline II helixtrans-57.3131.7173.8-173.2177.1-154.900110T193 N219T193-E217 HydrophobicContact CG2-CG 3.77Å; E217-N219 PolarHBondContact O-N 3.47Å
218F97.4Very high91.2Very high8 Ų865.7 Ų65.74%0.03537%0.365CS..PPolyproline II helixtrans-72.8118.7-176.9-168.2-87.6000110.1I195 M202 R203 A206 W212 S216 F220 V223 Y224I195-F218 HydrophobicContact CD1-CD1 3.82Å; I195-F218 HydrophobicContact CD1-CE1 4.2Å; M202-F218 HydrophobicContact CE-CD1 4.25Å; M202-F218 HydrophobicContact CE-CE1 3.49Å; M202-F218 VanDerWaalsContact CE-CE1 3.49Å; M202-F218 HydrophobicContact CE-CZ 3.94Å; M202-F218 HydrophobicContact SD-CE1 4.4Å; R203-F218 HydrophobicContact CB-CD2 4.49Å; R203-F218 HydrophobicContact CB-CE2 4.34Å; R203-F218 HydrophobicContact CG-CD2 3.93Å; R203-F218 HydrophobicContact CG-CE2 3.93Å; R203-F218 HydrophobicContact CG-CG 4.24Å; R203-F218 HydrophobicContact CG-CZ 4.25Å; A206-F218 HydrophobicContact CB-CE2 4.23Å; W212-F218 HydrophobicContact CB-CE2 4.36Å; W212-F218 AromaticContact CD2-CD2 3.49Å; W212-F218 HydrophobicContact CD2-CD2 3.49Å; W212-F218 VanDerWaalsContact CD2-CD2 3.49Å; W212-F218 HydrophobicContact CD2-CE2 4.02Å; W212-F218 AromaticContact CE2-CD2 3.8Å; W212-F218 AromaticContact CE3-CD2 3.55Å; W212-F218 HydrophobicContact CE3-CD2 3.55Å; W212-F218 AromaticContact CE3-CE2 3.91Å; W212-F218 HydrophobicContact CE3-CE2 3.91Å; W212-F218 AromaticContact CG-CD2 3.92Å; W212-F218 HydrophobicContact CG-CD2 3.92Å; W212-F218 HydrophobicContact CG-CE2 4.18Å; W212-F218 HydrophobicContact CH2-CD2 4.31Å; W212-F218 HydrophobicContact CZ2-CB 4.21Å; W212-F218 HydrophobicContact CZ2-CD2 4.22Å; W212-F218 AromaticContact CZ3-CD2 3.97Å; W212-F218 HydrophobicContact CZ3-CD2 3.97Å; S216-F218 PolarHBondContact O-N 3.04Å; F218-F220 HydrophobicContact CE1-CB 4.22Å; F218-F220 HydrophobicContact CE1-CD2 4.42Å; F218-V223 HydrophobicContact CD2-CG2 4.37Å; F218-V223 HydrophobicContact CE2-CB 4.3Å; F218-V223 HydrophobicContact CE2-CG1 3.95Å; F218-V223 HydrophobicContact CE2-CG2 4.04Å; F218-V223 HydrophobicContact CZ-CB 4.15Å; F218-V223 HydrophobicContact CZ-CG1 3.96Å; F218-V223 HydrophobicContact CZ-CG2 4.28Å; F218-Y224 HydrophobicContact CZ-CD2 4.4Å; F218-Y224 AromaticContact CZ-CE2 3.92Å; F218-Y224 HydrophobicContact CZ-CE2 3.92Å
219N97.4Very high89.5Confident34 Ų3464 Ų6418%0.18235%0.351CS..  trans-120.8110.4176.5-179.8-55.4000109T192 T193 E217 A221 T222 V223T192-N219 WeakPolarHBondContact CB-ND2 3.46Å; T192-N219 WeakPolarHBondContact O-CA 3.22Å; T193-N219 HydrophobicContact CG2-CB 3.94Å; E217-N219 PolarHBondContact O-N 3.47Å; N219-A221 PolarHBondContact O-N 2.82Å; N219-T222 PolarHBondContact O-N 3.4Å; N219-T222 WeakPolarHBondContact OD1-CB 3.45Å; N219-T222 PolarHBondContact OD1-N 2.71Å; N219-T222 PolarHBondContact OD1-OG1 2.91Å; N219-V223 WeakPolarHBondContact O-CB 3.25Å; N219-V223 VanDerWaalsContact O-CG2 3.26Å; N219-V223 WeakPolarHBondContact O-CG2 3.41Å; N219-V223 PolarHBondContact O-N 2.98Å
220F97.1Very high87.6Confident0 Ų062.5 Ų62.50%036%0.358CS..Hα-helixtrans-59.7-51.9-169.9178.3-95.9000112.2E167 A174 Y189 I191 T192 I195 M202 F218 T222 V223 Y224E167-F220 HydrophobicContact CB-CD1 4.26Å; E167-F220 HydrophobicContact CB-CE1 3.52Å; E167-F220 HydrophobicContact CB-CZ 4.18Å; A174-F220 HydrophobicContact CB-CB 4.21Å; A174-F220 HydrophobicContact CB-CD1 4.29Å; A174-F220 HydrophobicContact CB-CD2 3.58Å; A174-F220 HydrophobicContact CB-CE2 3.95Å; A174-F220 HydrophobicContact CB-CG 3.76Å; A174-F220 HydrophobicContact CB-CZ 4.46Å; Y189-F220 HydrophobicContact CD1-CD1 4.35Å; Y189-F220 AromaticContact CD1-CE1 3.55Å; Y189-F220 HydrophobicContact CD1-CE1 3.55Å; Y189-F220 HydrophobicContact CD1-CZ 4.39Å; Y189-F220 AromaticContact CE1-CE1 3.85Å; Y189-F220 HydrophobicContact CE1-CE1 3.85Å; Y189-F220 HydrophobicContact CE1-CZ 4.25Å; Y189-F220 HydrophobicContact CG-CE1 4.04Å; I191-F220 HydrophobicContact CB-CB 4.36Å; I191-F220 HydrophobicContact CB-CD1 4.2Å; I191-F220 HydrophobicContact CG2-CB 4.14Å; I191-F220 WeakPolarHBondContact O-CB 3.29Å; T192-F220 PolarHBondContact O-N 2.88Å; I195-F220 HydrophobicContact CD1-CB 4.18Å; M202-F220 HydrophobicContact CE-CD2 4.24Å; M202-F220 HydrophobicContact SD-CD2 3.44Å; M202-F220 WeakPolarHBondContact SD-CD2 3.48Å; M202-F220 HydrophobicContact SD-CE2 3.51Å; M202-F220 VanDerWaalsContact SD-CE2 3.51Å; F218-F220 HydrophobicContact CE1-CB 4.22Å; F218-F220 HydrophobicContact CE1-CD2 4.42Å; F220-T222 VanDerWaalsContact C-N 3.31Å; F220-T222 PolarHBondContact O-N 2.98Å; F220-V223 PolarHBondContact O-N 2.83Å; F220-Y224 AromaticContact CD2-CD2 3.51Å; F220-Y224 HydrophobicContact CD2-CD2 3.51Å; F220-Y224 AromaticContact CD2-CE2 3.89Å; F220-Y224 HydrophobicContact CD2-CE2 3.89Å; F220-Y224 HydrophobicContact CD2-CG 4.36Å; F220-Y224 AromaticContact CE2-CD2 3.48Å; F220-Y224 HydrophobicContact CE2-CD2 3.48Å; F220-Y224 VanDerWaalsContact CE2-CD2 3.48Å; F220-Y224 AromaticContact CE2-CE2 3.8Å; F220-Y224 HydrophobicContact CE2-CE2 3.8Å; F220-Y224 AromaticContact CE2-CG 3.99Å; F220-Y224 HydrophobicContact CE2-CG 3.99Å; F220-Y224 HydrophobicContact CG-CD2 4.29Å; F220-Y224 HydrophobicContact CZ-CD2 4.22Å; F220-Y224 HydrophobicContact CZ-CG 4.32Å; F220-Y224 PolarHBondContact O-N 3.36Å
221A94.1Very high86Confident13 Ų1362.7 Ų62.711%0.10734%0.339CS..Hα-helixtrans-57.1-43.4178.300000112Y189 I191 N219 S225Y189-A221 WeakPolarHBondContact O-CB 3.35Å; I191-A221 VanDerWaalsContact O-CB 3.22Å; I191-A221 WeakPolarHBondContact O-CB 3.49Å; I191-A221 PolarHBondContact O-N 2.83Å; N219-A221 PolarHBondContact O-N 2.82Å; A221-S225 WeakPolarHBondContact O-CA 3.49Å; A221-S225 WeakPolarHBondContact O-CB 3.31Å; A221-S225 PolarHBondContact O-N 3.32Å
222T93Very high84.4Confident88 Ų8861.5 Ų61.554%0.5434%0.337SS..Hα-helixtrans-66.6-41.8179.1-56.70000112.3N219 F220N219-T222 PolarHBondContact O-N 3.4Å; N219-T222 WeakPolarHBondContact OD1-CB 3.45Å; N219-T222 PolarHBondContact OD1-N 2.71Å; N219-T222 PolarHBondContact OD1-OG1 2.91Å; F220-T222 VanDerWaalsContact C-N 3.31Å; F220-T222 PolarHBondContact O-N 2.98Å
223V95.8Very high82.7Confident8 Ų865.5 Ų65.55%0.04836%0.357CS..Hα-helixtrans-74-40.8-174.8169.50000111.7R97 A206 W211 W212 F218 N219 F220R97-V223 WeakPolarHBondContact CD-O 3.19Å; R97-V223 PolarHBondContact NE-O 3.03Å; A206-V223 HydrophobicContact CB-CG1 3.59Å; W211-V223 HydrophobicContact CB-CG1 4.04Å; W212-V223 HydrophobicContact CB-CG1 4.12Å; W212-V223 HydrophobicContact CB-CG2 4.02Å; W212-V223 HydrophobicContact CG-CG2 4.27Å; F218-V223 HydrophobicContact CD2-CG2 4.37Å; F218-V223 HydrophobicContact CE2-CB 4.3Å; F218-V223 HydrophobicContact CE2-CG1 3.95Å; F218-V223 HydrophobicContact CE2-CG2 4.04Å; F218-V223 HydrophobicContact CZ-CB 4.15Å; F218-V223 HydrophobicContact CZ-CG1 3.96Å; F218-V223 HydrophobicContact CZ-CG2 4.28Å; N219-V223 WeakPolarHBondContact O-CB 3.25Å; N219-V223 VanDerWaalsContact O-CG2 3.26Å; N219-V223 WeakPolarHBondContact O-CG2 3.41Å; N219-V223 PolarHBondContact O-N 2.98Å; F220-V223 PolarHBondContact O-N 2.83Å
224Y95.1Very high81.1Confident0 Ų063.3 Ų63.30%035%0.349CS..Hα-helixtrans-98.7-14.7-173.9-78.8-86.3000114.6G96 R97 S169 M202 A206 W211 F218 F220G96-Y224 CarbonylContact C-O 3.34Å; G96-Y224 WeakPolarHBondContact CA-O 3.31Å; R97-Y224 PolarHBondContact N-O 3.12Å; S169-Y224 VanDerWaalsContact OG-CD1 3.3Å; S169-Y224 WeakPolarHBondContact OG-CD1 3.22Å; M202-Y224 HydrophobicContact CG-CE2 3.57Å; M202-Y224 WeakPolarHBondContact CG-OH 3.04Å; M202-Y224 PolarHBondContact O-OH 3.44Å; M202-Y224 HydrophobicContact SD-CE2 4.03Å; A206-Y224 HydrophobicContact CB-CE2 4.32Å; W211-Y224 HydrophobicContact CE3-CD1 4.14Å; W211-Y224 HydrophobicContact CE3-CE1 4.07Å; W211-Y224 AromaticContact CZ3-CD1 3.8Å; W211-Y224 HydrophobicContact CZ3-CD1 3.8Å; W211-Y224 AromaticContact CZ3-CE1 3.67Å; W211-Y224 HydrophobicContact CZ3-CE1 3.67Å; F218-Y224 HydrophobicContact CZ-CD2 4.4Å; F218-Y224 AromaticContact CZ-CE2 3.92Å; F218-Y224 HydrophobicContact CZ-CE2 3.92Å; F220-Y224 AromaticContact CD2-CD2 3.51Å; F220-Y224 HydrophobicContact CD2-CD2 3.51Å; F220-Y224 AromaticContact CD2-CE2 3.89Å; F220-Y224 HydrophobicContact CD2-CE2 3.89Å; F220-Y224 HydrophobicContact CD2-CG 4.36Å; F220-Y224 AromaticContact CE2-CD2 3.48Å; F220-Y224 HydrophobicContact CE2-CD2 3.48Å; F220-Y224 VanDerWaalsContact CE2-CD2 3.48Å; F220-Y224 AromaticContact CE2-CE2 3.8Å; F220-Y224 HydrophobicContact CE2-CE2 3.8Å; F220-Y224 AromaticContact CE2-CG 3.99Å; F220-Y224 HydrophobicContact CE2-CG 3.99Å; F220-Y224 HydrophobicContact CG-CD2 4.29Å; F220-Y224 HydrophobicContact CZ-CD2 4.22Å; F220-Y224 HydrophobicContact CZ-CG 4.32Å; F220-Y224 PolarHBondContact O-N 3.36Å
225S89.9Confident79.6Confident18 Ų1861.9 Ų61.913%0.12634%0.335CS..SBendtrans-80.3159.9175.3-165.70000113.1R97 A221R97-S225 WeakPolarHBondContact CG-O 3.46Å; R97-S225 PolarHBondContact NE-O 3Å; A221-S225 WeakPolarHBondContact O-CA 3.49Å; A221-S225 WeakPolarHBondContact O-CB 3.31Å; A221-S225 PolarHBondContact O-N 3.32Å
226F81.3Confident78.4Confident90 Ų9053.9 Ų53.940%0.39531%0.305SS..  trans-79.3144.2161.8-64.4-70.8000110.1G96 R97 T228 T229 I232G96-F226 VanDerWaalsContact C-CZ 3.41Å; G96-F226 WeakPolarHBondContact O-CE2 3.39Å; G96-F226 WeakPolarHBondContact O-CZ 3.3Å; R97-F226 HydrophobicContact CB-CE1 4.47Å; R97-F226 HydrophobicContact CG-CD1 4.22Å; R97-F226 HydrophobicContact CG-CE1 4.31Å; F226-T228 VanDerWaalsContact C-N 3.32Å; F226-T228 PolarHBondContact O-N 2.94Å; F226-T229 HydrophobicContact CB-CG2 4.18Å; F226-I232 HydrophobicContact CB-CD1 3.96Å; F226-I232 WeakPolarHBondContact O-CD1 3.29Å
227L57.5Low77.7Confident149 Ų14955.1 Ų55.178%0.7831%0.31SS*.SBendtrans-68.6-27.3-176.4-82.9159.6000113.7
228T57.1Low77.1Confident107 Ų10748.5 Ų48.566%0.65628%0.278SS*.  trans-163.6108.9-179.532.20000111.2F226F226-T228 VanDerWaalsContact C-N 3.32Å; F226-T228 PolarHBondContact O-N 2.94Å
229T60.7Low76.6Confident53 Ų5350.4 Ų50.433%0.32529%0.286SS..  trans-132.1148.9159.969.80000108.5F226 R231 I232 E233F226-T229 HydrophobicContact CB-CG2 4.18Å; T229-R231 PolarHBondContact O-N 2.83Å; T229-I232 HydrophobicContact CG2-CD1 4.45Å; T229-I232 PolarHBondContact O-N 3Å; T229-I232 WeakPolarHBondContact OG1-CD1 3.41Å; T229-I232 WeakPolarHBondContact OG1-CG1 3.26Å; T229-I232 PolarHBondContact OG1-N 2.79Å; T229-E233 PolarHBondContact O-N 2.97Å; T229-E233 VanDerWaalsContact O-N 3.1Å
230A58Low76.2Confident72 Ų7252.4 Ų52.460%0.59530%0.301SS*.Hα-helixtrans-55.9-28179.800000113S234A230-S234 PolarHBondContact O-N 2.63Å; A230-S234 VanDerWaalsContact O-N 3.09Å
231R61.6Low75.9Confident67 Ų6756.2 Ų56.225%0.25332%0.319SS..Hα-helixtrans-66.2-44.6174.1-63.2-170.2-168.7-174.97.7112F2 W95 T229 E233 S234 A235F2-R231 HydrophobicContact CB-CG 4.46Å; W95-R231 VanDerWaalsContact CE2-NH1 3.29Å; T229-R231 PolarHBondContact O-N 2.83Å; R231-E233 VanDerWaalsContact C-N 3.32Å; R231-S234 PolarHBondContact O-N 3.27Å; R231-A235 WeakPolarHBondContact O-CB 3.46Å; R231-A235 PolarHBondContact O-N 2.84Å
232I62.7Low75.9Confident28 Ų2855.6 Ų55.614%0.14431%0.314CS..Hα-helixtrans-65.9-37.8177.7-65.1166.7000110.2F226 T229 A235 G236F226-I232 HydrophobicContact CB-CD1 3.96Å; F226-I232 WeakPolarHBondContact O-CD1 3.29Å; T229-I232 HydrophobicContact CG2-CD1 4.45Å; T229-I232 PolarHBondContact O-N 3Å; T229-I232 WeakPolarHBondContact OG1-CD1 3.41Å; T229-I232 WeakPolarHBondContact OG1-CG1 3.26Å; T229-I232 PolarHBondContact OG1-N 2.79Å; I232-A235 PolarHBondContact O-N 2.94Å; I232-G236 PolarHBondContact O-N 2.75Å
233E61.5Low75.9Confident118 Ų11855.7 Ų55.755%0.55131%0.307SS*.Hα-helixtrans-63.8-43.6176.2-68.4173.9177.500112.2T229 R231 G236 T237T229-E233 PolarHBondContact O-N 2.97Å; T229-E233 VanDerWaalsContact O-N 3.1Å; R231-E233 VanDerWaalsContact C-N 3.32Å; E233-G236 PolarHBondContact O-N 2.72Å; E233-T237 PolarHBondContact O-N 2.92Å; E233-T237 PolarHBondContact O-OG1 3.48Å
234S61.3Low75.9Confident53 Ų5357.2 Ų57.237%0.37132%0.318SS..Hα-helixtrans-64.6-48.1175-169.90000111.7A230 R231 G236 T237 R238A230-S234 PolarHBondContact O-N 2.63Å; A230-S234 VanDerWaalsContact O-N 3.09Å; R231-S234 PolarHBondContact O-N 3.27Å; S234-G236 VanDerWaalsContact C-N 3.3Å; S234-G236 PolarHBondContact O-N 3.1Å; S234-T237 WeakPolarHBondContact O-CB 3.11Å; S234-T237 PolarHBondContact O-N 2.82Å; S234-T237 VanDerWaalsContact O-N 3.14Å; S234-R238 PolarHBondContact O-N 3.48Å; S234-R238 VanDerWaalsContact O-N 3.07Å
235A63Low75.9Confident0 Ų058.3 Ų58.30%032%0.323CS..Hα-helixtrans-61.8-38.5177.100000111.7N187 Q188 R231 I232 T237 R238 Y239N187-A235 HydrophobicContact CB-CB 4.09Å; Q188-A235 HydrophobicContact CB-CB 4.28Å; Q188-A235 HydrophobicContact CG-CB 4.39Å; R231-A235 WeakPolarHBondContact O-CB 3.46Å; R231-A235 PolarHBondContact O-N 2.84Å; I232-A235 PolarHBondContact O-N 2.94Å; A235-T237 VanDerWaalsContact C-N 3.31Å; A235-T237 PolarHBondContact O-N 3.24Å; A235-R238 PolarHBondContact O-N 3.21Å; A235-Y239 WeakPolarHBondContact O-CB 3.5Å; A235-Y239 PolarHBondContact O-N 3.38Å
236G69.6Low76.2Confident17 Ų1757.4 Ų57.418%0.17532%0.317CS..Hα-helixtrans-62.9-37.5174.500000112.6I232 E233 S234 C240I232-G236 PolarHBondContact O-N 2.75Å; E233-G236 PolarHBondContact O-N 2.72Å; S234-G236 VanDerWaalsContact C-N 3.3Å; S234-G236 PolarHBondContact O-N 3.1Å; G236-C240 WeakPolarHBondContact O-CB 3.44Å; G236-C240 PolarHBondContact O-N 3.1Å; G236-C240 VanDerWaalsContact O-N 3.09Å; G236-C240 PolarHBondContact O-SG 2.98Å
237T80.4Confident76.9Confident85 Ų8558.5 Ų58.552%0.52132%0.324SS..Hα-helixtrans-65.7-51.4175.7-55.40000110.5E233 S234 A235 Y239 C240 E241E233-T237 PolarHBondContact O-N 2.92Å; E233-T237 PolarHBondContact O-OG1 3.48Å; S234-T237 WeakPolarHBondContact O-CB 3.11Å; S234-T237 PolarHBondContact O-N 2.82Å; S234-T237 VanDerWaalsContact O-N 3.14Å; A235-T237 VanDerWaalsContact C-N 3.31Å; A235-T237 PolarHBondContact O-N 3.24Å; T237-Y239 PolarHBondContact O-N 2.94Å; T237-C240 WeakPolarHBondContact O-CB 3.34Å; T237-C240 PolarHBondContact O-N 2.71Å; T237-C240 VanDerWaalsContact O-N 3.16Å; T237-E241 WeakPolarHBondContact O-CG 3.42Å; T237-E241 PolarHBondContact O-N 2.92Å
238R85Confident78.7Confident10 Ų1058.6 Ų58.64%0.03832%0.318CS..Hα-helixtrans-64.9-38.9178.6-60.7-156.4-42.517816.1113.2S5 C6 D7 D28 S234 A235 C240 E241 G242 G268 M271S5-R238 PolarHBondContact O-NH1 3.36Å; S5-R238 VanDerWaalsContact O-NH1 3.14Å; S5-R238 PolarHBondContact O-NH2 3.24Å; C6-R238 PolarHBondContact O-NH2 3.46Å; D7-R238 IonicContact OD1-CZ 2.92Å; D7-R238 IonicContact OD1-NE 2.94Å; D7-R238 PolarHBondContact OD1-NE 3.09Å; D7-R238 IonicContact OD1-NH2 3.38Å; D7-R238 PolarHBondContact OD1-NH2 3.37Å; D7-R238 IonicContact OD2-CZ 3.91Å; D7-R238 IonicContact OD2-NE 2.82Å; D7-R238 PolarHBondContact OD2-NE 3.24Å; D7-R238 IonicContact OD2-NH1 3.68Å; D7-R238 IonicContact OD2-NH2 3.18Å; D7-R238 PolarHBondContact OD2-NH2 3.41Å; D28-R238 IonicContact OD2-NH1 3.04Å; D28-R238 PolarHBondContact OD2-NH1 2.76Å; D28-R238 IonicContact OD2-NH2 3.96Å; S234-R238 PolarHBondContact O-N 3.48Å; S234-R238 VanDerWaalsContact O-N 3.07Å; A235-R238 PolarHBondContact O-N 3.21Å; R238-C240 VanDerWaalsContact C-N 3.28Å; R238-C240 PolarHBondContact O-N 3.29Å; R238-E241 PolarHBondContact O-N 3.12Å; R238-G242 PolarHBondContact O-N 3.12Å; R238-G268 WeakPolarHBondContact CD-O 3.35Å; R238-G268 PolarHBondContact NH1-O 2.58Å; R238-G268 VanDerWaalsContact NH1-O 3.14Å; R238-M271 VanDerWaalsContact NH1-CG 3.34Å; R238-M271 PolarHBondContact NH1-SD 3.08Å
239Y86.8Confident80.6Confident49 Ų4957.8 Ų57.819%0.19230%0.303CS..Hα-helixtrans-55.6-45.6172.9173.7-96.5000111.3R183 N184 A235 T237 K243R183-Y239 PolarHBondContact NH1-OH 3.49Å; R183-Y239 VanDerWaalsContact NH1-OH 3.12Å; N184-Y239 WeakPolarHBondContact ND2-CD2 3.17Å; N184-Y239 PolarHBondContact ND2-O 3.22Å; N184-Y239 WeakPolarHBondContact O-CE2 3.22Å; A235-Y239 WeakPolarHBondContact O-CB 3.5Å; A235-Y239 PolarHBondContact O-N 3.38Å; T237-Y239 PolarHBondContact O-N 2.94Å; Y239-K243 VanDerWaalsContact O-CB 3.29Å; Y239-K243 WeakPolarHBondContact O-CB 3.37Å; Y239-K243 PolarHBondContact O-N 3.39Å
240C88.3Confident82.2Confident75 Ų7559.4 Ų59.451%0.50731%0.309SS..Hα-helixtrans-66.9-44.4177.6-67.80000112.3G236 T237 R238 K243 S244G236-C240 WeakPolarHBondContact O-CB 3.44Å; G236-C240 PolarHBondContact O-N 3.1Å; G236-C240 VanDerWaalsContact O-N 3.09Å; G236-C240 PolarHBondContact O-SG 2.98Å; T237-C240 WeakPolarHBondContact O-CB 3.34Å; T237-C240 PolarHBondContact O-N 2.71Å; T237-C240 VanDerWaalsContact O-N 3.16Å; R238-C240 VanDerWaalsContact C-N 3.28Å; R238-C240 PolarHBondContact O-N 3.29Å; C240-K243 PolarHBondContact O-N 3.33Å; C240-S244 WeakPolarHBondContact O-CB 3.46Å; C240-S244 PolarHBondContact O-N 3.05Å
241E92.2Very high83.9Confident80 Ų8057.4 Ų57.437%0.37430%0.295SS..Hα-helixtrans-64.7-46.2178-69.6-55.8144.800111.9T237 R238 K243 S244 L245T237-E241 WeakPolarHBondContact O-CG 3.42Å; T237-E241 PolarHBondContact O-N 2.92Å; R238-E241 PolarHBondContact O-N 3.12Å; E241-K243 VanDerWaalsContact C-N 3.33Å; E241-K243 PolarHBondContact O-N 3.13Å; E241-S244 CarbonylContact O-C 3.54Å; E241-S244 WeakPolarHBondContact O-CA 3.28Å; E241-S244 WeakPolarHBondContact O-CB 3.33Å; E241-S244 PolarHBondContact O-N 2.84Å; E241-S244 VanDerWaalsContact O-N 3.1Å; E241-L245 WeakPolarHBondContact O-CG 3.1Å; E241-L245 PolarHBondContact O-N 3.4Å
242G92.5Very high85.5Confident0 Ų060.6 Ų60.60%031%0.313CS..Hα-helixtrans-59.3-42.1174.800000112.7R238 L245 L246R238-G242 PolarHBondContact O-N 3.12Å; G242-L245 PolarHBondContact O-N 3.25Å; G242-L246 PolarHBondContact O-N 2.86Å
243K93.4Very high87.2Confident91 Ų9159.2 Ų59.240%0.39631%0.306SS..Hα-helixtrans-62.4-43.6172.8-176.5-179.1175.1-1770111.7Y182 Y239 C240 E241 L245 L246 E247Y182-K243 HydrophobicContact CE2-CG 4.24Å; Y239-K243 VanDerWaalsContact O-CB 3.29Å; Y239-K243 WeakPolarHBondContact O-CB 3.37Å; Y239-K243 PolarHBondContact O-N 3.39Å; C240-K243 PolarHBondContact O-N 3.33Å; E241-K243 VanDerWaalsContact C-N 3.33Å; E241-K243 PolarHBondContact O-N 3.13Å; K243-L245 VanDerWaalsContact C-N 3.33Å; K243-L245 PolarHBondContact O-N 2.92Å; K243-L246 PolarHBondContact O-N 3.09Å; K243-E247 WeakPolarHBondContact O-CB 3.47Å; K243-E247 PolarHBondContact O-N 2.75Å
244S95.4Very high88.9Confident39 Ų3954.9 Ų54.927%0.27329%0.288SS..Hα-helixtrans-61.1-40.5177.1176.90000111.8C240 E241 E247 K248C240-S244 WeakPolarHBondContact O-CB 3.46Å; C240-S244 PolarHBondContact O-N 3.05Å; E241-S244 CarbonylContact O-C 3.54Å; E241-S244 WeakPolarHBondContact O-CA 3.28Å; E241-S244 WeakPolarHBondContact O-CB 3.33Å; E241-S244 PolarHBondContact O-N 2.84Å; E241-S244 VanDerWaalsContact O-N 3.1Å; S244-E247 PolarHBondContact O-N 3.11Å; S244-K248 VanDerWaalsContact O-CG 3.24Å; S244-K248 WeakPolarHBondContact O-CG 3.32Å; S244-K248 PolarHBondContact O-N 3.11Å
245L95.6Very high90.6Very high23 Ų2352.6 Ų52.612%0.1227%0.272CS..Hα-helixtrans-65.7-41.3176.2-71.4169.8000112.7E241 G242 K243 I261 D264 I269E241-L245 WeakPolarHBondContact O-CG 3.1Å; E241-L245 PolarHBondContact O-N 3.4Å; G242-L245 PolarHBondContact O-N 3.25Å; K243-L245 VanDerWaalsContact C-N 3.33Å; K243-L245 PolarHBondContact O-N 2.92Å; L245-I261 HydrophobicContact CB-CD1 4.24Å; L245-I261 HydrophobicContact CB-CG1 4.05Å; L245-I261 HydrophobicContact CD1-CG2 4.3Å; L245-D264 HydrophobicContact CD1-CB 4.22Å; L245-I269 HydrophobicContact CD1-CD1 3.48Å; L245-I269 VanDerWaalsContact CD1-CD1 3.48Å
246L95.9Very high92.2Very high0 Ų056.7 Ų56.70%029%0.291CS..Hα-helixtrans-63.8-45.6172-71.1173.4000111.5F9 Y182 N184 G242 K243 K248 R249 N250 I253 M258 I261F9-L246 HydrophobicContact CD1-CD1 3.75Å; F9-L246 HydrophobicContact CD1-CD2 4.42Å; F9-L246 HydrophobicContact CD1-CG 4.1Å; Y182-L246 HydrophobicContact CD2-CB 3.6Å; Y182-L246 HydrophobicContact CD2-CD1 3.77Å; Y182-L246 HydrophobicContact CD2-CG 4.33Å; Y182-L246 HydrophobicContact CE2-CB 3.95Å; Y182-L246 HydrophobicContact CG-CB 4.04Å; Y182-L246 HydrophobicContact CG-CD1 4.31Å; N184-L246 HydrophobicContact CB-CD1 4.16Å; G242-L246 PolarHBondContact O-N 2.86Å; K243-L246 PolarHBondContact O-N 3.09Å; L246-K248 PolarHBondContact O-N 3.41Å; L246-R249 CarbonylContact O-C 3.44Å; L246-R249 PolarHBondContact O-N 3.49Å; L246-N250 PolarHBondContact O-N 2.88Å; L246-I253 HydrophobicContact CB-CD1 4.46Å; L246-I253 HydrophobicContact CD2-CD1 3.83Å; L246-M258 HydrophobicContact CD2-CE 4.06Å; L246-I261 HydrophobicContact CD2-CD1 3.81Å; L246-I261 HydrophobicContact CG-CD1 4.33Å
247E95.9Very high93.6Very high113 Ų11356 Ų5653%0.52828%0.283SS..Hα-helixtrans-60.4-42.4-178.6-175.1166.2-171.500112.3Y182 K243 S244 R249 N250Y182-E247 HydrophobicContact CE2-CB 4.48Å; Y182-E247 VanDerWaalsContact OH-CB 3.28Å; Y182-E247 WeakPolarHBondContact OH-CB 3.5Å; Y182-E247 WeakPolarHBondContact OH-CG 3.35Å; K243-E247 WeakPolarHBondContact O-CB 3.47Å; K243-E247 PolarHBondContact O-N 2.75Å; S244-E247 PolarHBondContact O-N 3.11Å; E247-R249 PolarHBondContact O-N 3.19Å; E247-R249 VanDerWaalsContact O-N 3.09Å; E247-N250 WeakPolarHBondContact O-CB 3.26Å; E247-N250 PolarHBondContact O-N 3.04Å; E247-N250 VanDerWaalsContact O-N 3.14Å
248K96.3Very high94.5Very high150 Ų15052 Ų5265%0.65226%0.259SS*.THydrogen-bonded Turntrans-58.1-22.8174.8-75.2167.4-172.8168.70113.4S244 L246S244-K248 VanDerWaalsContact O-CG 3.24Å; S244-K248 WeakPolarHBondContact O-CG 3.32Å; S244-K248 PolarHBondContact O-N 3.11Å; L246-K248 PolarHBondContact O-N 3.41Å
249R95.9Very high95.1Very high91 Ų9151.5 Ų51.534%0.34326%0.257SS..THydrogen-bonded Turntrans-113.68.1-177.1-59.5-173-179.7-118.716.1112.8L246 E247 G251 H252 I253 D260L246-R249 CarbonylContact O-C 3.44Å; L246-R249 PolarHBondContact O-N 3.49Å; E247-R249 PolarHBondContact O-N 3.19Å; E247-R249 VanDerWaalsContact O-N 3.09Å; R249-G251 PolarHBondContact O-N 3.16Å; R249-H252 CarbonylContact O-C 3.58Å; R249-H252 WeakPolarHBondContact O-CA 3.39Å; R249-H252 PolarHBondContact O-N 3.41Å; R249-I253 HydrophobicContact CB-CG1 3.99Å; R249-I253 VanDerWaalsContact O-CG1 3.27Å; R249-I253 WeakPolarHBondContact O-CG1 3.37Å; R249-I253 PolarHBondContact O-N 3.37Å; R249-D260 IonicContact CZ-OD2 2.75Å; R249-D260 IonicContact NH1-OD2 3.19Å; R249-D260 IonicContact NH2-OD2 3.76Å; R249-D260 PolarHBondContact NH2-OD2 2.76Å
250N94.8Very high95.6Very high87 Ų8752.7 Ų52.747%0.46527%0.266SS..THydrogen-bonded Turntrans-55.8127.9-177.2-175.931.1000111.5S15 Y182 L246 E247 H252S15-N250 VanDerWaalsContact CB-OD1 3.22Å; S15-N250 WeakPolarHBondContact CB-OD1 3.18Å; S15-N250 PolarHBondContact OG-OD1 2.8Å; Y182-N250 HydrophobicContact CE1-CB 4Å; L246-N250 PolarHBondContact O-N 2.88Å; E247-N250 WeakPolarHBondContact O-CB 3.26Å; E247-N250 PolarHBondContact O-N 3.04Å; E247-N250 VanDerWaalsContact O-N 3.14Å; N250-H252 VanDerWaalsContact C-N 3.33Å
251G93.4Very high96.1Very high29 Ų2949.2 Ų49.230%0.29924%0.243SC..THydrogen-bonded Turntrans91.3-11.1-175.200000114.4P14 S15 R249P14-G251 WeakPolarHBondContact O-CA 3.47Å; S15-G251 CarbonylContact O-C 3.59Å; S15-G251 WeakPolarHBondContact O-CA 3.49Å; S15-G251 PolarHBondContact O-N 3.03Å; R249-G251 PolarHBondContact O-N 3.16Å
252H94.9Very high96.3Very high134 Ų13445.4 Ų45.462%0.6223%0.225SC*.  trans-138.223.8-174.3-57.9-65.5000112.1S15 R249 N250 T254S15-H252 PolarHBondContact O-N 2.79Å; S15-H252 VanDerWaalsContact O-N 3.16Å; R249-H252 CarbonylContact O-C 3.58Å; R249-H252 WeakPolarHBondContact O-CA 3.39Å; R249-H252 PolarHBondContact O-N 3.41Å; N250-H252 VanDerWaalsContact C-N 3.33Å; H252-T254 PolarHBondContact O-N 3.43Å
253I98Very high96.6Very high0 Ų046.8 Ų46.80%023%0.23CC..BIsolated β-bridgetrans-72.9114.7178.7-56.2178.6000107.7A11 S15 S16 E17 I22 L246 R249 M258A11-I253 HydrophobicContact CB-CB 4Å; A11-I253 HydrophobicContact CB-CD1 3.64Å; A11-I253 HydrophobicContact CB-CG1 4.39Å; A11-I253 HydrophobicContact CB-CG2 3.79Å; S15-I253 PolarHBondContact O-N 3.28Å; S15-I253 VanDerWaalsContact O-N 3.17Å; S15-I253 WeakPolarHBondContact OG-CD1 3.36Å; S16-I253 CarbonylContact C-O 3.54Å; S16-I253 WeakPolarHBondContact CA-O 3.32Å; E17-I253 PolarHBondContact N-O 2.69Å; I22-I253 HydrophobicContact CD1-CG2 4.22Å; I22-I253 WeakPolarHBondContact CD1-O 3.37Å; L246-I253 HydrophobicContact CB-CD1 4.46Å; L246-I253 HydrophobicContact CD2-CD1 3.83Å; R249-I253 HydrophobicContact CB-CG1 3.99Å; R249-I253 VanDerWaalsContact O-CG1 3.27Å; R249-I253 WeakPolarHBondContact O-CG1 3.37Å; R249-I253 PolarHBondContact O-N 3.37Å; I253-M258 HydrophobicContact CG2-CE 4.24Å
254T97.6Very high96.7Very high27 Ų2744.6 Ų44.617%0.16622%0.223CC..  trans-106.2177.7171.873.50000111.6E17 H252 E256 A257 M258E17-T254 HydrophobicContact CB-CG2 3.96Å; E17-T254 WeakPolarHBondContact OE2-CG2 3.31Å; H252-T254 PolarHBondContact O-N 3.43Å; T254-E256 WeakPolarHBondContact CB-OE2 3.46Å; T254-E256 PolarHBondContact OG1-N 3.29Å; T254-E256 VanDerWaalsContact OG1-N 3.16Å; T254-E256 PolarHBondContact OG1-OE2 2.75Å; T254-A257 PolarHBondContact O-N 2.73Å; T254-A257 PolarHBondContact OG1-N 2.93Å; T254-A257 VanDerWaalsContact OG1-N 3.08Å; T254-M258 PolarHBondContact O-N 3.2Å
255A97.6Very high96.6Very high4 Ų445.3 Ų45.33%0.03322%0.221CC..Hα-helixtrans-60.1-44.416800000111.7A257 M258 M259 V282 V284 M383A255-A257 VanDerWaalsContact C-N 3.33Å; A255-A257 PolarHBondContact O-N 2.81Å; A255-M258 PolarHBondContact O-N 3.02Å; A255-M259 VanDerWaalsContact O-CG 3.29Å; A255-M259 WeakPolarHBondContact O-CG 3.2Å; A255-M259 PolarHBondContact O-N 3.1Å; A255-V282 HydrophobicContact CB-CG1 4.37Å; A255-V284 HydrophobicContact CB-CG2 3.56Å; A255-M383 HydrophobicContact CB-CE 3.62Å
256E97.6Very high96.4Very high87 Ų8752.2 Ų52.241%0.40726%0.258SS..Hα-helixtrans-61.2-44.3176.7-63.191.8172.500111T254 M258 M259 D260 M383T254-E256 WeakPolarHBondContact CB-OE2 3.46Å; T254-E256 PolarHBondContact OG1-N 3.29Å; T254-E256 VanDerWaalsContact OG1-N 3.16Å; T254-E256 PolarHBondContact OG1-OE2 2.75Å; E256-M258 VanDerWaalsContact C-N 3.28Å; E256-M258 PolarHBondContact O-N 3.27Å; E256-M259 PolarHBondContact O-N 2.86Å; E256-M259 VanDerWaalsContact O-N 3.17Å; E256-D260 PolarHBondContact O-N 2.75Å; E256-M383 HydrophobicContact CB-CE 4.35Å; E256-M383 VanDerWaalsContact CD-CE 3.48Å; E256-M383 HydrophobicContact CG-CE 3.49Å; E256-M383 VanDerWaalsContact CG-CE 3.49Å; E256-M383 HydrophobicContact CG-SD 4.06Å
257A97.8Very high96.1Very high2 Ų252.9 Ų52.92%0.01726%0.263CS..Hα-helixtrans-58-41.7177.200000112.1T254 A255 D260 I261T254-A257 PolarHBondContact O-N 2.73Å; T254-A257 PolarHBondContact OG1-N 2.93Å; T254-A257 VanDerWaalsContact OG1-N 3.08Å; A255-A257 VanDerWaalsContact C-N 3.33Å; A255-A257 PolarHBondContact O-N 2.81Å; A257-D260 PolarHBondContact O-N 3.35Å; A257-I261 WeakPolarHBondContact O-CG1 3.36Å; A257-I261 PolarHBondContact O-N 2.65Å; A257-I261 VanDerWaalsContact O-N 3.11Å
258M98.6Very high95.8Very high0 Ų048.6 Ų48.60%025%0.249CC..Hα-helixtrans-68-41.9176.6-170.562.27400111.6F9 I22 L246 I253 T254 A255 E256 D260 I261 L262 V282F9-M258 HydrophobicContact CB-CE 3.79Å; F9-M258 HydrophobicContact CB-SD 3.65Å; F9-M258 HydrophobicContact CD2-SD 4.39Å; F9-M258 HydrophobicContact CG-SD 4.14Å; I22-M258 HydrophobicContact CG2-CB 3.79Å; I22-M258 HydrophobicContact CG2-CE 3.92Å; I22-M258 HydrophobicContact CG2-CG 4.06Å; L246-M258 HydrophobicContact CD2-CE 4.06Å; I253-M258 HydrophobicContact CG2-CE 4.24Å; T254-M258 PolarHBondContact O-N 3.2Å; A255-M258 PolarHBondContact O-N 3.02Å; E256-M258 VanDerWaalsContact C-N 3.28Å; E256-M258 PolarHBondContact O-N 3.27Å; M258-D260 VanDerWaalsContact C-N 3.29Å; M258-D260 PolarHBondContact O-N 2.85Å; M258-I261 WeakPolarHBondContact O-CB 3.43Å; M258-I261 PolarHBondContact O-N 2.83Å; M258-L262 WeakPolarHBondContact O-CG 3.26Å; M258-L262 PolarHBondContact O-N 2.75Å; M258-V282 HydrophobicContact CB-CG1 4.16Å; M258-V282 HydrophobicContact CB-CG2 4.27Å; M258-V282 HydrophobicContact CG-CG1 4.2Å; M258-V282 HydrophobicContact CG-CG2 3.89Å
259M98.6Very high95.6Very high0 Ų041.5 Ų41.50%022%0.218CC..Hα-helixtrans-62.5-36.1175.3-66.7175.6-171.600112.1A255 E256 L262 R263 V282 Y296 F308 M383A255-M259 VanDerWaalsContact O-CG 3.29Å; A255-M259 WeakPolarHBondContact O-CG 3.2Å; A255-M259 PolarHBondContact O-N 3.1Å; E256-M259 PolarHBondContact O-N 2.86Å; E256-M259 VanDerWaalsContact O-N 3.17Å; M259-L262 PolarHBondContact O-N 2.84Å; M259-R263 WeakPolarHBondContact O-CD 3.48Å; M259-R263 VanDerWaalsContact O-CG 3.24Å; M259-R263 WeakPolarHBondContact O-CG 3.21Å; M259-R263 PolarHBondContact O-N 2.86Å; M259-V282 HydrophobicContact CE-CB 4.21Å; M259-V282 HydrophobicContact CE-CG1 4.4Å; M259-V282 HydrophobicContact CG-CB 4.26Å; M259-V282 HydrophobicContact CG-CG2 3.68Å; M259-Y296 HydrophobicContact CE-CD1 3.86Å; M259-Y296 HydrophobicContact CE-CD2 3.8Å; M259-Y296 HydrophobicContact CE-CE1 4.3Å; M259-Y296 HydrophobicContact CE-CE2 4.25Å; M259-Y296 HydrophobicContact CE-CG 3.59Å; M259-F308 HydrophobicContact CB-CD2 3.96Å; M259-F308 HydrophobicContact CB-CE2 3.77Å; M259-F308 HydrophobicContact CB-CZ 4.4Å; M259-F308 HydrophobicContact CE-CB 3.62Å; M259-F308 HydrophobicContact CE-CD1 4.31Å; M259-F308 HydrophobicContact CE-CD2 4.32Å; M259-F308 HydrophobicContact CE-CG 3.85Å; M259-F308 HydrophobicContact CG-CD1 4.3Å; M259-F308 HydrophobicContact CG-CD2 3.54Å; M259-F308 HydrophobicContact CG-CE1 4.39Å; M259-F308 HydrophobicContact CG-CE2 3.68Å; M259-F308 HydrophobicContact CG-CG 3.9Å; M259-F308 HydrophobicContact CG-CZ 4.11Å; M259-F308 HydrophobicContact SD-CB 3.77Å; M259-F308 HydrophobicContact SD-CD2 3.58Å; M259-F308 VanDerWaalsContact SD-CD2 3.58Å; M259-F308 HydrophobicContact SD-CE2 4.33Å; M259-F308 HydrophobicContact SD-CG 3.73Å; M259-M383 HydrophobicContact CE-CE 3.99Å; M259-M383 HydrophobicContact CE-CG 4.44Å; M259-M383 HydrophobicContact CE-SD 3.88Å; M259-M383 HydrophobicContact SD-CE 4.11Å; M259-M383 HydrophobicContact SD-SD 3.65Å; M259-M383 VanDerWaalsContact SD-SD 3.65Å
260D98Very high95.6Very high74 Ų7437.3 Ų37.340%0.39620%0.203SC..Hα-helixtrans-63-44.6173.1-70.7-16.8000111.3R249 E256 A257 M258 L262 R263 D264R249-D260 IonicContact CZ-OD2 2.75Å; R249-D260 IonicContact NH1-OD2 3.19Å; R249-D260 IonicContact NH2-OD2 3.76Å; R249-D260 PolarHBondContact NH2-OD2 2.76Å; E256-D260 PolarHBondContact O-N 2.75Å; A257-D260 PolarHBondContact O-N 3.35Å; M258-D260 VanDerWaalsContact C-N 3.29Å; M258-D260 PolarHBondContact O-N 2.85Å; D260-L262 VanDerWaalsContact C-N 3.33Å; D260-L262 PolarHBondContact O-N 3.17Å; D260-R263 WeakPolarHBondContact O-CB 3.46Å; D260-R263 PolarHBondContact O-N 3.16Å; D260-R263 VanDerWaalsContact O-N 3.11Å; D260-D264 PolarHBondContact O-N 2.76Å
261I97.4Very high95.4Very high3 Ų334 Ų342%0.01519%0.185CC..Hα-helixtrans-59.4-46.6177-69171.7000110.2F9 L245 L246 A257 M258 R263 D264 I269F9-I261 HydrophobicContact CD1-CG2 4.44Å; F9-I261 HydrophobicContact CE1-CG2 4.05Å; F9-I261 HydrophobicContact CE2-CG2 4.15Å; F9-I261 HydrophobicContact CZ-CG2 3.91Å; L245-I261 HydrophobicContact CB-CD1 4.24Å; L245-I261 HydrophobicContact CB-CG1 4.05Å; L245-I261 HydrophobicContact CD1-CG2 4.3Å; L246-I261 HydrophobicContact CD2-CD1 3.81Å; L246-I261 HydrophobicContact CG-CD1 4.33Å; A257-I261 WeakPolarHBondContact O-CG1 3.36Å; A257-I261 PolarHBondContact O-N 2.65Å; A257-I261 VanDerWaalsContact O-N 3.11Å; M258-I261 WeakPolarHBondContact O-CB 3.43Å; M258-I261 PolarHBondContact O-N 2.83Å; I261-R263 PolarHBondContact O-N 3.19Å; I261-D264 WeakPolarHBondContact O-CB 3.38Å; I261-D264 PolarHBondContact O-N 3.35Å; I261-D264 VanDerWaalsContact O-N 3.12Å; I261-I269 HydrophobicContact CG2-CD1 3.84Å; I261-I269 WeakPolarHBondContact O-CG2 3.14Å
262L98Very high95.2Very high0 Ų037.2 Ų37.20%019%0.192CC..Hα-helixtrans-65.7-17.5179.1-65.1-176000113.4F9 N26 M258 M259 D260 I269 N270 M281 V282 P303 F308F9-L262 HydrophobicContact CD2-CD2 3.81Å; F9-L262 HydrophobicContact CE2-CD2 3.75Å; N26-L262 HydrophobicContact CB-CD2 4.47Å; N26-L262 PolarHBondContact ND2-O 3.23Å; M258-L262 WeakPolarHBondContact O-CG 3.26Å; M258-L262 PolarHBondContact O-N 2.75Å; M259-L262 PolarHBondContact O-N 2.84Å; D260-L262 VanDerWaalsContact C-N 3.33Å; D260-L262 PolarHBondContact O-N 3.17Å; L262-I269 HydrophobicContact CD2-CG2 4.46Å; L262-N270 WeakPolarHBondContact O-CB 3.28Å; L262-M281 WeakPolarHBondContact CD1-O 3.32Å; L262-V282 HydrophobicContact CD1-CG2 3.59Å; L262-P303 WeakPolarHBondContact O-CG 3.35Å; L262-F308 HydrophobicContact CB-CZ 4.46Å; L262-F308 HydrophobicContact CD1-CE1 4.36Å; L262-F308 HydrophobicContact CD1-CZ 4.09Å
263R97.6Very high95Very high28 Ų2833.1 Ų33.111%0.10619%0.186CC..Hα-helixtrans-91.2-11.9176.2-74.7171.7174.5128.77.5114.1M259 D260 I261 K265 N270 P303 E379M259-R263 WeakPolarHBondContact O-CD 3.48Å; M259-R263 VanDerWaalsContact O-CG 3.24Å; M259-R263 WeakPolarHBondContact O-CG 3.21Å; M259-R263 PolarHBondContact O-N 2.86Å; D260-R263 WeakPolarHBondContact O-CB 3.46Å; D260-R263 PolarHBondContact O-N 3.16Å; D260-R263 VanDerWaalsContact O-N 3.11Å; I261-R263 PolarHBondContact O-N 3.19Å; R263-K265 PolarHBondContact O-N 2.88Å; R263-K265 VanDerWaalsContact O-N 3.07Å; R263-N270 WeakPolarHBondContact O-CB 3.25Å; R263-N270 PolarHBondContact O-ND2 3.33Å; R263-P303 HydrophobicContact CG-CB 3.85Å; R263-P303 HydrophobicContact CG-CG 4.23Å; R263-P303 PolarHBondContact NE-O 2.84Å; R263-P303 PolarHBondContact NH2-O 2.9Å; R263-E379 IonicContact CZ-OE1 2.68Å; R263-E379 VanDerWaalsContact CZ-OE1 3.29Å; R263-E379 IonicContact CZ-OE2 2.65Å; R263-E379 IonicContact NH1-OE1 3.55Å; R263-E379 PolarHBondContact NH1-OE1 3.14Å; R263-E379 IonicContact NH1-OE2 2.83Å; R263-E379 IonicContact NH2-OE1 2.86Å; R263-E379 PolarHBondContact NH2-OE1 2.99Å; R263-E379 IonicContact NH2-OE2 3.65Å; R263-E379 PolarHBondContact NH2-OE2 2.71Å
264D96.1Very high94.4Very high46 Ų4639.4 Ų39.425%0.24622%0.217CC..  trans-70.4105.2-169.3-167.2-77.6000111.3L245 D260 I261 D266 S267 I269 N270L245-D264 HydrophobicContact CD1-CB 4.22Å; D260-D264 PolarHBondContact O-N 2.76Å; I261-D264 WeakPolarHBondContact O-CB 3.38Å; I261-D264 PolarHBondContact O-N 3.35Å; I261-D264 VanDerWaalsContact O-N 3.12Å; D264-D266 PolarHBondContact OD1-N 3.5Å; D264-S267 PolarHBondContact O-OG 2.8Å; D264-S267 WeakPolarHBondContact OD1-CB 3.48Å; D264-S267 PolarHBondContact OD1-N 2.8Å; D264-S267 PolarHBondContact OD1-OG 3.47Å; D264-I269 PolarHBondContact O-N 2.91Å; D264-N270 PolarHBondContact O-N 2.88Å
265K92.8Very high94.1Very high54 Ų5439.8 Ų39.824%0.23522%0.217CC..THydrogen-bonded Turntrans-78.8-31.4178.6-70-177.8176.7174.90112.4R263 S267 G268 N270 E272 D302 E304R263-K265 PolarHBondContact O-N 2.88Å; R263-K265 VanDerWaalsContact O-N 3.07Å; K265-S267 VanDerWaalsContact C-N 3.33Å; K265-S267 PolarHBondContact O-N 2.9Å; K265-G268 PolarHBondContact O-N 3.37Å; K265-N270 WeakPolarHBondContact CE-ND2 3.49Å; K265-N270 HydrophobicContact CG-CB 3.85Å; K265-E272 WeakPolarHBondContact CE-OE1 3.12Å; K265-E272 VanDerWaalsContact NZ-CD 3.29Å; K265-E272 IonicContact NZ-OE1 3.29Å; K265-E272 PolarHBondContact NZ-OE1 2.74Å; K265-E272 IonicContact NZ-OE2 2.81Å; K265-D302 IonicContact NZ-OD1 3.16Å; K265-D302 IonicContact NZ-OD2 3.66Å; K265-D302 PolarHBondContact NZ-OD2 3.02Å; K265-E304 VanDerWaalsContact CE-OE2 3.25Å; K265-E304 WeakPolarHBondContact CE-OE2 3.47Å; K265-E304 IonicContact NZ-OE2 2.72Å; K265-E304 PolarHBondContact NZ-OE2 2.68Å
266D91.3Very high93.9Very high167 Ų16741.2 Ų41.289%0.89322%0.223SC*.THydrogen-bonded Turntrans-65.4-37.2-176.3-72.9-15.4000111.9D264 G268D264-D266 PolarHBondContact OD1-N 3.5Å; D266-G268 VanDerWaalsContact C-N 3.28Å
267S89.9Confident93.8Very high14 Ų1437 Ų3710%0.09820%0.204CC..THydrogen-bonded Turntrans-76.5-12.4172.159.80000114.1D264 K265 I269D264-S267 PolarHBondContact O-OG 2.8Å; D264-S267 WeakPolarHBondContact OD1-CB 3.48Å; D264-S267 PolarHBondContact OD1-N 2.8Å; D264-S267 PolarHBondContact OD1-OG 3.47Å; K265-S267 VanDerWaalsContact C-N 3.33Å; K265-S267 PolarHBondContact O-N 2.9Å; S267-I269 VanDerWaalsContact C-N 3.31Å; S267-I269 VanDerWaalsContact OG-CD1 3.31Å; S267-I269 WeakPolarHBondContact OG-CD1 3.18Å; S267-I269 VanDerWaalsContact OG-CG1 3.3Å; S267-I269 WeakPolarHBondContact OG-CG1 3.5Å; S267-I269 PolarHBondContact OG-N 2.95Å
268G89.8Confident93.8Very high24 Ų2437 Ų3725%0.24720%0.203CC..THydrogen-bonded Turntrans77.49-173.700000115.1R238 K265 D266 M271R238-G268 WeakPolarHBondContact CD-O 3.35Å; R238-G268 PolarHBondContact NH1-O 2.58Å; R238-G268 VanDerWaalsContact NH1-O 3.14Å; K265-G268 PolarHBondContact O-N 3.37Å; D266-G268 VanDerWaalsContact C-N 3.28Å; G268-M271 WeakPolarHBondContact O-CG 3.24Å
269I92.3Very high93.7Very high0 Ų037 Ų370%020%0.203CC..SBendtrans-67.9-41.8176.6-68.1168.1000110.8D7 F9 N26 L245 I261 L262 D264 S267D7-I269 HydrophobicContact CB-CG2 4.47Å; D7-I269 WeakPolarHBondContact OD2-CA 3.49Å; F9-I269 HydrophobicContact CE1-CD1 4.42Å; F9-I269 HydrophobicContact CE2-CG2 4.13Å; F9-I269 HydrophobicContact CZ-CD1 3.8Å; F9-I269 HydrophobicContact CZ-CG1 4.21Å; F9-I269 HydrophobicContact CZ-CG2 4.17Å; N26-I269 PolarHBondContact ND2-O 3.19Å; L245-I269 HydrophobicContact CD1-CD1 3.48Å; L245-I269 VanDerWaalsContact CD1-CD1 3.48Å; I261-I269 HydrophobicContact CG2-CD1 3.84Å; I261-I269 WeakPolarHBondContact O-CG2 3.14Å; L262-I269 HydrophobicContact CD2-CG2 4.46Å; D264-I269 PolarHBondContact O-N 2.91Å; S267-I269 VanDerWaalsContact C-N 3.31Å; S267-I269 VanDerWaalsContact OG-CD1 3.31Å; S267-I269 WeakPolarHBondContact OG-CD1 3.18Å; S267-I269 VanDerWaalsContact OG-CG1 3.3Å; S267-I269 WeakPolarHBondContact OG-CG1 3.5Å; S267-I269 PolarHBondContact OG-N 2.95Å
270N94.9Very high93.7Very high4 Ų437 Ų372%0.02120%0.203CC..SBendtrans-90105.6167.7-175.84.6000109.1L262 R263 D264 K265 D302 P303L262-N270 WeakPolarHBondContact O-CB 3.28Å; R263-N270 WeakPolarHBondContact O-CB 3.25Å; R263-N270 PolarHBondContact O-ND2 3.33Å; D264-N270 PolarHBondContact O-N 2.88Å; K265-N270 WeakPolarHBondContact CE-ND2 3.49Å; K265-N270 HydrophobicContact CG-CB 3.85Å; N270-D302 PolarHBondContact ND2-OD1 3.02Å; N270-P303 WeakPolarHBondContact OD1-CD 3.35Å
271M91.5Very high93.8Very high16 Ų1633.5 Ų33.58%0.07918%0.184CC..  trans-90142.8-176-74.9-157.8-4.400113.2S4 S5 D28 R238 G268 F275 M276 T277S4-M271 WeakPolarHBondContact OG-CE 3.48Å; S4-M271 PolarHBondContact OG-SD 2.89Å; S5-M271 VanDerWaalsContact O-SD 3.39Å; D28-M271 HydrophobicContact CB-CE 3.99Å; D28-M271 HydrophobicContact CB-SD 4.46Å; R238-M271 VanDerWaalsContact NH1-CG 3.34Å; R238-M271 PolarHBondContact NH1-SD 3.08Å; G268-M271 WeakPolarHBondContact O-CG 3.24Å; M271-F275 HydrophobicContact CE-CB 3.5Å; M271-F275 VanDerWaalsContact CE-CB 3.5Å; M271-M276 VanDerWaalsContact O-CA 3.24Å; M271-M276 WeakPolarHBondContact O-CA 3.49Å; M271-M276 WeakPolarHBondContact O-CB 3.04Å; M271-T277 PolarHBondContact N-OG1 3.11Å; M271-T277 PolarHBondContact O-N 3.2Å
272E89.5Confident93.8Very high97 Ų9733.3 Ų33.345%0.45318%0.184SC..  trans-130.1145.7170.6-67-174.7142.700111.1K265 F275 R305K265-E272 WeakPolarHBondContact CE-OE1 3.12Å; K265-E272 VanDerWaalsContact NZ-CD 3.29Å; K265-E272 IonicContact NZ-OE1 3.29Å; K265-E272 PolarHBondContact NZ-OE1 2.74Å; K265-E272 IonicContact NZ-OE2 2.81Å; E272-F275 CarbonylContact C-O 3.6Å; E272-R305 IonicContact OE1-CZ 3.59Å; E272-R305 IonicContact OE1-NE 3.18Å; E272-R305 IonicContact OE1-NH2 3.54Å; E272-R305 PolarHBondContact OE1-NH2 2.76Å
273G89.1Confident93.9Very high49 Ų4933.4 Ų33.451%0.50518%0.184SC..SBendtrans134.7-149.8178.500000112.9C31 F275C31-G273 WeakPolarHBondContact CB-O 3.38Å; G273-F275 CarbonylContact C-O 3.55Å; G273-F275 PolarHBondContact N-O 3Å; G273-F275 PolarHBondContact O-N 2.87Å
274M87.3Confident93.9Very high131 Ų13132.1 Ų32.165%0.64518%0.179SC*.SBendtrans-64.6-30.6175.7-69.4-60.9-57.600112.4M1 P30 C31M1-M274 HydrophobicContact SD-CG 4.22Å; P30-M274 WeakPolarHBondContact CA-O 3.41Å; C31-M274 PolarHBondContact N-O 2.88Å
275F89.8Confident94Very high35 Ų3530.1 Ų30.115%0.15417%0.169CC..EExtended strand (participates in β ladder)trans-107.8139.1159.3-83.7-105.1000107.4P3 R29 P30 M143 M271 E272 G273P3-F275 HydrophobicContact CB-CD1 4.01Å; P3-F275 HydrophobicContact CB-CD2 4.16Å; P3-F275 HydrophobicContact CB-CE1 3.62Å; P3-F275 HydrophobicContact CB-CE2 3.78Å; P3-F275 HydrophobicContact CB-CG 4.27Å; P3-F275 HydrophobicContact CB-CZ 3.49Å; P3-F275 VanDerWaalsContact CB-CZ 3.49Å; P3-F275 HydrophobicContact CG-CE2 4.39Å; P3-F275 HydrophobicContact CG-CZ 4.08Å; R29-F275 VanDerWaalsContact O-CA 3.29Å; R29-F275 WeakPolarHBondContact O-CA 3.47Å; P30-F275 HydrophobicContact CG-CE1 3.91Å; P30-F275 HydrophobicContact CG-CE2 4.41Å; P30-F275 HydrophobicContact CG-CZ 3.79Å; M143-F275 HydrophobicContact CE-CE1 4.44Å; M143-F275 HydrophobicContact CE-CE2 4.34Å; M143-F275 HydrophobicContact CE-CZ 3.54Å; M271-F275 HydrophobicContact CE-CB 3.5Å; M271-F275 VanDerWaalsContact CE-CB 3.5Å; E272-F275 CarbonylContact C-O 3.6Å; G273-F275 CarbonylContact C-O 3.55Å; G273-F275 PolarHBondContact N-O 3Å; G273-F275 PolarHBondContact O-N 2.87Å
276M93.7Very high94.3Very high34 Ų3427.7 Ų27.717%0.16716%0.159CC..EExtended strand (participates in β ladder)trans-144.1163.2177.175.5-172.5-49.200110.5D28 R29 C31 M271 T278 P301D28-M276 WeakPolarHBondContact CA-O 3.15Å; R29-M276 PolarHBondContact N-O 2.8Å; R29-M276 PolarHBondContact O-N 3.34Å; C31-M276 HydrophobicContact CB-CB 4.47Å; C31-M276 HydrophobicContact CB-CG 3.9Å; C31-M276 HydrophobicContact CB-SD 3.53Å; C31-M276 VanDerWaalsContact CB-SD 3.53Å; M271-M276 VanDerWaalsContact O-CA 3.24Å; M271-M276 WeakPolarHBondContact O-CA 3.49Å; M271-M276 WeakPolarHBondContact O-CB 3.04Å; M276-T278 HydrophobicContact CG-CG2 3.96Å; M276-T278 PolarHBondContact O-N 2.83Å; M276-P301 HydrophobicContact CE-CB 4Å; M276-P301 HydrophobicContact SD-CB 4.04Å
277T96.4Very high94.6Very high0 Ų022.3 Ų22.30%013%0.132CC..EExtended strand (participates in β ladder)trans-65.9105.7168.2-56.40000108.9N26 D28 M271 S280 P301 D302 P303N26-T277 HydrophobicContact CB-CG2 3.74Å; N26-T277 VanDerWaalsContact CG-CG2 3.46Å; D28-T277 WeakPolarHBondContact OD1-CA 3.41Å; D28-T277 VanDerWaalsContact OD1-CB 3.26Å; D28-T277 WeakPolarHBondContact OD1-CB 3.43Å; D28-T277 PolarHBondContact OD1-N 2.96Å; D28-T277 PolarHBondContact OD1-OG1 2.94Å; M271-T277 PolarHBondContact N-OG1 3.11Å; M271-T277 PolarHBondContact O-N 3.2Å; T277-S280 WeakPolarHBondContact CG2-OG 3.45Å; T277-P301 CarbonylContact O-C 3.57Å; T277-P301 VanDerWaalsContact O-CA 3.25Å; T277-P301 WeakPolarHBondContact O-CA 3.5Å; T277-D302 PolarHBondContact O-N 3.41Å; T277-P303 HydrophobicContact CG2-CG 4.19Å
278T96.7Very high94.9Very high1 Ų125.5 Ų25.51%0.00615%0.148CC..EExtended strand (participates in β ladder)trans-91.2-19.1-175.751.20000112.8S27 R29 Q35 M276 T300S27-T278 PolarHBondContact O-N 3.44Å; S27-T278 PolarHBondContact O-OG1 3.34Å; R29-T278 HydrophobicContact CB-CG2 3.81Å; R29-T278 WeakPolarHBondContact CB-OG1 3.48Å; R29-T278 WeakPolarHBondContact CG-OG1 3.23Å; Q35-T278 WeakPolarHBondContact CB-O 3.44Å; Q35-T278 WeakPolarHBondContact CG-OG1 3.35Å; M276-T278 HydrophobicContact CG-CG2 3.96Å; M276-T278 PolarHBondContact O-N 2.83Å; T278-T300 CarbonylContact O-C 3.58Å; T278-T300 VanDerWaalsContact O-C 3.31Å
279G97.3Very high95.2Very high0 Ų029.2 Ų29.20%017%0.17CC..EExtended strand (participates in β ladder)trans-163.8153.517400000111S27 M80 T298S27-G279 PolarHBondContact N-O 3.08Å; M80-G279 WeakPolarHBondContact CE-O 3.3Å; G279-T298 WeakPolarHBondContact CA-OG1 3.27Å
280S98.6Very high95.3Very high0 Ų033 Ų330%020%0.202CC..EExtended strand (participates in β ladder)trans-136148179.3-51.90000111K25 N26 T277 F297 T298 P303K25-S280 CarbonylContact O-C 3.56Å; K25-S280 VanDerWaalsContact O-CA 3.28Å; K25-S280 WeakPolarHBondContact O-CA 3.46Å; N26-S280 VanDerWaalsContact OD1-CB 3.26Å; N26-S280 WeakPolarHBondContact OD1-CB 3.43Å; N26-S280 PolarHBondContact OD1-OG 2.94Å; T277-S280 WeakPolarHBondContact CG2-OG 3.45Å; S280-F297 WeakPolarHBondContact O-CA 3.35Å; S280-T298 PolarHBondContact N-OG1 2.9Å; S280-T298 PolarHBondContact O-N 2.85Å; S280-P303 WeakPolarHBondContact OG-CB 3.37Å; S280-P303 WeakPolarHBondContact OG-CG 3.36Å
281M98.8Very high95.4Very high0 Ų034.2 Ų34.20%021%0.208CC..EExtended strand (participates in β ladder)trans-130.7139.7177.4177.8-178.3172.100110.6F23 G24 K25 M80 A82 L262 S283 Y296 F297F23-M281 HydrophobicContact CE1-SD 4.5Å; G24-M281 CarbonylContact C-O 3.59Å; G24-M281 VanDerWaalsContact CA-O 3.26Å; G24-M281 WeakPolarHBondContact CA-O 3.35Å; K25-M281 PolarHBondContact N-O 2.71Å; K25-M281 PolarHBondContact O-N 2.74Å; M80-M281 HydrophobicContact CB-SD 3.85Å; M80-M281 HydrophobicContact CE-CB 4.15Å; M80-M281 HydrophobicContact CG-CB 4.05Å; M80-M281 HydrophobicContact CG-SD 4.01Å; M80-M281 HydrophobicContact SD-CB 3.34Å; M80-M281 WeakPolarHBondContact SD-CB 3.16Å; M80-M281 HydrophobicContact SD-CG 4.48Å; M80-M281 HydrophobicContact SD-SD 4.43Å; A82-M281 HydrophobicContact CB-CE 3.92Å; L262-M281 WeakPolarHBondContact CD1-O 3.32Å; M281-S283 WeakPolarHBondContact CE-OG 3.44Å; M281-Y296 CarbonylContact C-O 3.5Å; M281-Y296 VanDerWaalsContact CA-O 3.24Å; M281-Y296 WeakPolarHBondContact CA-O 3.32Å; M281-F297 HydrophobicContact CB-CD1 3.9Å; M281-F297 HydrophobicContact CB-CE1 3.92Å; M281-F297 HydrophobicContact CE-CE1 4.1Å; M281-F297 HydrophobicContact CE-CZ 3.83Å; M281-F297 HydrophobicContact CG-CD1 3.86Å; M281-F297 HydrophobicContact CG-CE1 3.47Å; M281-F297 VanDerWaalsContact CG-CE1 3.47Å; M281-F297 HydrophobicContact CG-CZ 3.95Å; M281-F297 HydrophobicContact SD-CD1 4.27Å; M281-F297 HydrophobicContact SD-CE1 3.34Å; M281-F297 WeakPolarHBondContact SD-CE1 3.27Å; M281-F297 HydrophobicContact SD-CZ 3.72Å
282V98.9Very high95.6Very high0 Ų034.5 Ų34.50%021%0.211CC..EExtended strand (participates in β ladder)trans-128.8135.3163.1174.60000108.6I22 F23 A255 M258 M259 L262 Y296 F308I22-V282 HydrophobicContact CG2-CG1 4.36Å; F23-V282 CarbonylContact O-C 3.45Å; F23-V282 WeakPolarHBondContact O-CA 3.25Å; A255-V282 HydrophobicContact CB-CG1 4.37Å; M258-V282 HydrophobicContact CB-CG1 4.16Å; M258-V282 HydrophobicContact CB-CG2 4.27Å; M258-V282 HydrophobicContact CG-CG1 4.2Å; M258-V282 HydrophobicContact CG-CG2 3.89Å; M259-V282 HydrophobicContact CE-CB 4.21Å; M259-V282 HydrophobicContact CE-CG1 4.4Å; M259-V282 HydrophobicContact CG-CB 4.26Å; M259-V282 HydrophobicContact CG-CG2 3.68Å; L262-V282 HydrophobicContact CD1-CG2 3.59Å; V282-Y296 PolarHBondContact N-O 3.02Å; V282-Y296 WeakPolarHBondContact O-CD2 3.27Å; V282-Y296 PolarHBondContact O-N 3Å; V282-F308 HydrophobicContact CG2-CD1 4.37Å; V282-F308 HydrophobicContact CG2-CE1 3.9Å; V282-F308 HydrophobicContact CG2-CZ 4.29Å
283S98.9Very high96Very high1 Ų129.9 Ų29.91%0.00719%0.189CC..EExtended strand (participates in β ladder)trans-124.3140.8173-67.80000111.5I22 F23 C88 M281 V294 H295I22-S283 CarbonylContact C-O 3.56Å; I22-S283 VanDerWaalsContact CA-O 3.27Å; I22-S283 WeakPolarHBondContact CA-O 3.19Å; F23-S283 PolarHBondContact N-O 3.11Å; F23-S283 PolarHBondContact O-N 3.18Å; C88-S283 VanDerWaalsContact SG-CB 3.6Å; M281-S283 WeakPolarHBondContact CE-OG 3.44Å; S283-V294 WeakPolarHBondContact CA-O 3.41Å; S283-H295 WeakPolarHBondContact CB-ND1 3.33Å; S283-H295 PolarHBondContact OG-ND1 2.6Å
284V98.8Very high96.4Very high2 Ų227.5 Ų27.51%0.01217%0.165CC..EExtended strand (participates in β ladder)trans-120.4114.9175.4-171.20000108.1R20 I21 A255 G293 V294 Y296 L390R20-V284 HydrophobicContact CB-CG1 4.21Å; R20-V284 HydrophobicContact CG-CG1 4.36Å; I21-V284 WeakPolarHBondContact O-CA 3.29Å; A255-V284 HydrophobicContact CB-CG2 3.56Å; V284-G293 CarbonylContact O-C 3.39Å; V284-G293 WeakPolarHBondContact O-CA 3.41Å; V284-V294 PolarHBondContact N-O 3.19Å; V284-V294 PolarHBondContact O-N 3.46Å; V284-Y296 HydrophobicContact CG2-CE2 4.09Å; V284-L390 HydrophobicContact CB-CD1 4.03Å; V284-L390 HydrophobicContact CB-CD2 4.15Å; V284-L390 HydrophobicContact CG1-CD1 3.75Å; V284-L390 HydrophobicContact CG1-CD2 3.94Å
285V98.6Very high97Very high3 Ų321.3 Ų21.32%0.01813%0.134CC..EExtended strand (participates in β ladder)trans-124105-171.6174.40000109R20 I21 Q86 R160R20-V285 CarbonylContact C-O 3.51Å; R20-V285 WeakPolarHBondContact CA-O 3.49Å; I21-V285 HydrophobicContact CB-CB 4.34Å; I21-V285 PolarHBondContact N-O 3.46Å; I21-V285 PolarHBondContact O-N 3.47Å; Q86-V285 HydrophobicContact CB-CG1 3.68Å; Q86-V285 HydrophobicContact CB-CG2 4.14Å; Q86-V285 HydrophobicContact CG-CG1 4.33Å; R160-V285 HydrophobicContact CB-CG1 4.27Å; R160-V285 HydrophobicContact CG-CG1 3.36Å
286P98.2Very high97.4Very high4 Ų419.6 Ų19.63%0.02613%0.127CC..EExtended strand (participates in β ladder)trans-59.8141.5175.5-24.735.3000112.2R160 N288 L291 P292 L390R160-P286 PolarHBondContact NH1-O 3.17Å; P286-N288 PolarHBondContact O-N 3.19Å; P286-L291 HydrophobicContact CB-CB 3.89Å; P286-L291 HydrophobicContact CB-CD1 4.17Å; P286-L291 HydrophobicContact CG-CB 3.9Å; P286-L291 HydrophobicContact CG-CD1 4.49Å; P286-P292 WeakPolarHBondContact CD-O 3.48Å; P286-P292 WeakPolarHBondContact CG-O 3.42Å; P286-L390 HydrophobicContact CG-CD2 3.75Å
287T97.4Very high97.7Very high54 Ų5418 Ų1833%0.33112%0.119SC..SBendtrans-65.3-28.9171.855.80000111.9P13 Q19 I21 S289P13-T287 HydrophobicContact CG-CG2 4.31Å; Q19-T287 HydrophobicContact CB-CG2 4.44Å; Q19-T287 WeakPolarHBondContact CB-OG1 3.36Å; Q19-T287 WeakPolarHBondContact O-CB 3.46Å; Q19-T287 WeakPolarHBondContact O-CG2 3.29Å; Q19-T287 PolarHBondContact O-N 3.49Å; Q19-T287 PolarHBondContact O-OG1 3.25Å; I21-T287 HydrophobicContact CD1-CG2 3.6Å; T287-S289 PolarHBondContact O-N 3.1Å
288N96.7Very high97.8Very high81 Ų8118 Ų1843%0.43312%0.119SC..SBendtrans-68.6111.8173.1-179-2.9000110R160 P286 A290 L291R160-N288 PolarHBondContact NH1-O 3.19Å; P286-N288 PolarHBondContact O-N 3.19Å; N288-A290 PolarHBondContact O-N 3.18Å; N288-A290 VanDerWaalsContact O-N 3.14Å; N288-A290 WeakPolarHBondContact OD1-CB 3.23Å; N288-A290 PolarHBondContact OD1-N 3.36Å; N288-L291 HydrophobicContact CB-CD1 4.05Å; N288-L291 HydrophobicContact CB-CG 4.32Å; N288-L291 PolarHBondContact O-N 2.91Å
289S95.3Very high97.8Very high101 Ų10118 Ų1871%0.70612%0.119SC*.THydrogen-bonded Turntrans-64.6-16-178.359.60000114.5T287 L291T287-S289 PolarHBondContact O-N 3.1Å; S289-L291 VanDerWaalsContact C-N 3.28Å
290A94.6Very high97.8Very high81 Ų8118 Ų1867%0.66912%0.119SC*.THydrogen-bonded Turntrans-76.4-16.2174.400000113.1N288N288-A290 PolarHBondContact O-N 3.18Å; N288-A290 VanDerWaalsContact O-N 3.14Å; N288-A290 WeakPolarHBondContact OD1-CB 3.23Å; N288-A290 PolarHBondContact OD1-N 3.36Å
291L96.6Very high97.7Very high28 Ų2818.5 Ų18.515%0.14712%0.122CC..SBendtrans-100.5138-179.1-62.8173.1000110.1R160 P286 N288 S289 L390R160-L291 PolarHBondContact NH1-O 2.99Å; R160-L291 PolarHBondContact NH2-O 2.84Å; P286-L291 HydrophobicContact CB-CB 3.89Å; P286-L291 HydrophobicContact CB-CD1 4.17Å; P286-L291 HydrophobicContact CG-CB 3.9Å; P286-L291 HydrophobicContact CG-CD1 4.49Å; N288-L291 HydrophobicContact CB-CD1 4.05Å; N288-L291 HydrophobicContact CB-CG 4.32Å; N288-L291 PolarHBondContact O-N 2.91Å; S289-L291 VanDerWaalsContact C-N 3.28Å; L291-L390 WeakPolarHBondContact CD1-O 3.45Å
292P96.1Very high97.6Very high22 Ų2218.6 Ų18.614%0.14312%0.123CC..PPolyproline II helixtrans-69.9160.4174.636.9-41.5000110.5P286 V312 I389 V394P286-P292 WeakPolarHBondContact CD-O 3.48Å; P286-P292 WeakPolarHBondContact CG-O 3.42Å; P292-V312 HydrophobicContact CB-CG1 4.06Å; P292-I389 HydrophobicContact CB-CG2 4.47Å; P292-I389 HydrophobicContact CG-CG2 3.32Å; P292-V394 HydrophobicContact CB-CG2 4.32Å; P292-V394 HydrophobicContact CG-CG2 3.9Å
293G98.1Very high97.5Very high0 Ų018.6 Ų18.60%012%0.123CC..PPolyproline II helixtrans-88.3165.216000000111.6V284V284-G293 CarbonylContact O-C 3.39Å; V284-G293 WeakPolarHBondContact O-CA 3.41Å
294V98.6Very high97.3Very high0 Ų022.7 Ų22.70%014%0.142CC..EExtended strand (participates in β ladder)trans-124.7127.5175.1-178.70000108.1S283 V284 Y296 P310 V312 M386 I389 L390S283-V294 WeakPolarHBondContact CA-O 3.41Å; V284-V294 PolarHBondContact N-O 3.19Å; V284-V294 PolarHBondContact O-N 3.46Å; V294-Y296 HydrophobicContact CB-CE2 4.13Å; V294-Y296 HydrophobicContact CG1-CD2 4.19Å; V294-Y296 HydrophobicContact CG1-CE1 4.06Å; V294-Y296 HydrophobicContact CG1-CE2 3.56Å; V294-Y296 VanDerWaalsContact CG1-CZ 3.48Å; V294-P310 HydrophobicContact CG1-CB 3.99Å; V294-V312 HydrophobicContact CB-CG2 4.44Å; V294-V312 HydrophobicContact CG1-CG2 4.31Å; V294-V312 HydrophobicContact CG2-CG2 3.95Å; V294-M386 HydrophobicContact CG1-CB 3.98Å; V294-M386 HydrophobicContact CG1-CG 3.7Å; V294-M386 HydrophobicContact CG1-SD 3.81Å; V294-M386 HydrophobicContact CG2-CB 4.19Å; V294-M386 HydrophobicContact CG2-SD 4.27Å; V294-I389 HydrophobicContact CG2-CG2 4.37Å; V294-L390 HydrophobicContact CB-CD2 4.29Å; V294-L390 HydrophobicContact CB-CG 4.47Å; V294-L390 HydrophobicContact CG2-CD1 4.21Å; V294-L390 HydrophobicContact CG2-CD2 3.74Å; V294-L390 HydrophobicContact CG2-CG 3.71Å
295H98.8Very high97Very high0 Ų024 Ų240%015%0.147CC..EExtended strand (participates in β ladder)trans-116.9118.4-175.6-49.8-75.9000109.3A82 Q86 S283 F297 P310 F311 F313A82-H295 WeakPolarHBondContact CB-CE1 3.23Å; A82-H295 VanDerWaalsContact CB-ND1 3.32Å; A82-H295 WeakPolarHBondContact CB-ND1 3.47Å; Q86-H295 PolarHBondContact OE1-NE2 2.95Å; S283-H295 WeakPolarHBondContact CB-ND1 3.33Å; S283-H295 PolarHBondContact OG-ND1 2.6Å; H295-F297 HydrophobicContact CB-CE2 3.65Å; H295-F297 HydrophobicContact CB-CZ 4.2Å; H295-P310 CarbonylContact O-C 3.48Å; H295-F311 PolarHBondContact N-O 2.73Å; H295-F311 WeakPolarHBondContact O-CA 3.47Å; H295-F311 WeakPolarHBondContact O-CB 2.96Å; H295-F311 PolarHBondContact O-N 2.71Å; H295-F313 AromaticContact CD2-CD2 3.9Å; H295-F313 AromaticContact CD2-CE2 3.69Å; H295-F313 AromaticContact NE2-CD2 3.74Å; H295-F313 AromaticContact NE2-CE2 3.57Å
296Y98.9Very high96.9Very high0 Ų023.9 Ų23.90%015%0.146CC..EExtended strand (participates in β ladder)trans-103.6134.9-178.6-56.1-95.8000110.5M259 M281 V282 V284 V294 F308 K309 P310 M383 M386M259-Y296 HydrophobicContact CE-CD1 3.86Å; M259-Y296 HydrophobicContact CE-CD2 3.8Å; M259-Y296 HydrophobicContact CE-CE1 4.3Å; M259-Y296 HydrophobicContact CE-CE2 4.25Å; M259-Y296 HydrophobicContact CE-CG 3.59Å; M281-Y296 CarbonylContact C-O 3.5Å; M281-Y296 VanDerWaalsContact CA-O 3.24Å; M281-Y296 WeakPolarHBondContact CA-O 3.32Å; V282-Y296 PolarHBondContact N-O 3.02Å; V282-Y296 WeakPolarHBondContact O-CD2 3.27Å; V282-Y296 PolarHBondContact O-N 3Å; V284-Y296 HydrophobicContact CG2-CE2 4.09Å; V294-Y296 HydrophobicContact CB-CE2 4.13Å; V294-Y296 HydrophobicContact CG1-CD2 4.19Å; V294-Y296 HydrophobicContact CG1-CE1 4.06Å; V294-Y296 HydrophobicContact CG1-CE2 3.56Å; V294-Y296 VanDerWaalsContact CG1-CZ 3.48Å; Y296-F308 HydrophobicContact CD1-CB 4.45Å; Y296-K309 VanDerWaalsContact CA-O 3.29Å; Y296-K309 WeakPolarHBondContact CA-O 3.3Å; Y296-P310 HydrophobicContact CD1-CB 3.79Å; Y296-P310 HydrophobicContact CE1-CB 3.7Å; Y296-P310 HydrophobicContact CE1-CG 4.46Å; Y296-M383 HydrophobicContact CE1-CG 3.88Å; Y296-M386 HydrophobicContact CE1-CG 4.09Å; Y296-M386 WeakPolarHBondContact OH-CB 3.1Å
297F98.8Very high96.9Very high0 Ų023.7 Ų23.70%015%0.145CC..EExtended strand (participates in β ladder)trans-132.5145.6177.3-58.8-92.6000111.5V37 V68 S280 M281 H295 K309 F404V37-F297 HydrophobicContact CG1-CB 4Å; V37-F297 HydrophobicContact CG1-CD1 4.44Å; V37-F297 HydrophobicContact CG1-CD2 4.08Å; V37-F297 HydrophobicContact CG1-CG 3.93Å; V37-F297 HydrophobicContact CG2-CB 3.66Å; V37-F297 HydrophobicContact CG2-CD1 4.5Å; V37-F297 HydrophobicContact CG2-CG 4.24Å; V68-F297 HydrophobicContact CB-CE2 4.37Å; V68-F297 HydrophobicContact CB-CZ 4.48Å; V68-F297 HydrophobicContact CG1-CE2 3.74Å; V68-F297 HydrophobicContact CG1-CZ 3.78Å; V68-F297 HydrophobicContact CG2-CD2 4.32Å; V68-F297 HydrophobicContact CG2-CE2 3.68Å; V68-F297 HydrophobicContact CG2-CZ 4.02Å; S280-F297 WeakPolarHBondContact O-CA 3.35Å; M281-F297 HydrophobicContact CB-CD1 3.9Å; M281-F297 HydrophobicContact CB-CE1 3.92Å; M281-F297 HydrophobicContact CE-CE1 4.1Å; M281-F297 HydrophobicContact CE-CZ 3.83Å; M281-F297 HydrophobicContact CG-CD1 3.86Å; M281-F297 HydrophobicContact CG-CE1 3.47Å; M281-F297 VanDerWaalsContact CG-CE1 3.47Å; M281-F297 HydrophobicContact CG-CZ 3.95Å; M281-F297 HydrophobicContact SD-CD1 4.27Å; M281-F297 HydrophobicContact SD-CE1 3.34Å; M281-F297 WeakPolarHBondContact SD-CE1 3.27Å; M281-F297 HydrophobicContact SD-CZ 3.72Å; H295-F297 HydrophobicContact CB-CE2 3.65Å; H295-F297 HydrophobicContact CB-CZ 4.2Å; F297-K309 PolarHBondContact N-O 3.49Å; F297-K309 PolarHBondContact O-N 2.72Å; F297-F404 HydrophobicContact CB-CE2 4.06Å
298T98.4Very high97Very high0 Ų021.1 Ų21.10%013%0.129CC..  trans-81-42172.861.70000112.4G279 S280 T300 P303 V307 F308 K309G279-T298 WeakPolarHBondContact CA-OG1 3.27Å; S280-T298 PolarHBondContact N-OG1 2.9Å; S280-T298 PolarHBondContact O-N 2.85Å; T298-T300 PolarHBondContact O-N 2.82Å; T298-T300 PolarHBondContact O-OG1 3.26Å; T298-T300 PolarHBondContact OG1-O 2.87Å; T298-P303 HydrophobicContact CG2-CB 4.41Å; T298-V307 WeakPolarHBondContact CA-O 3.31Å; T298-F308 HydrophobicContact CG2-CD1 4.03Å; T298-F308 HydrophobicContact CG2-CD2 4.4Å; T298-F308 HydrophobicContact CG2-CE1 3.88Å; T298-F308 HydrophobicContact CG2-CE2 4.25Å; T298-F308 HydrophobicContact CG2-CG 4.28Å; T298-F308 HydrophobicContact CG2-CZ 3.99Å; T298-K309 WeakPolarHBondContact O-CE 3.35Å; T298-K309 PolarHBondContact O-NZ 2.92Å
299G96.6Very high97.1Very high0 Ų017.3 Ų17.30%011%0.108CC..  trans56.615.8-173.900000114.6V37 H348V37-G299 VanDerWaalsContact CG2-CA 3.5Å; G299-H348 PolarHBondContact O-CE1 3.06Å; G299-H348 VanDerWaalsContact O-CE1 3.24Å; G299-H348 PolarHBondContact O-NE2 3.28Å
300T97.3Very high97.2Very high1 Ų112.5 Ų12.51%0.0068%0.075CC..SBendtrans-151.9152.617947.30000109.3T278 T298 S306 L350 H354T278-T300 CarbonylContact O-C 3.58Å; T278-T300 VanDerWaalsContact O-C 3.31Å; T298-T300 PolarHBondContact O-N 2.82Å; T298-T300 PolarHBondContact O-OG1 3.26Å; T298-T300 PolarHBondContact OG1-O 2.87Å; T300-S306 WeakPolarHBondContact CB-OG 3.13Å; T300-S306 PolarHBondContact O-OG 2.86Å; T300-S306 VanDerWaalsContact OG1-CB 3.3Å; T300-S306 WeakPolarHBondContact OG1-CB 3.34Å; T300-S306 PolarHBondContact OG1-OG 3.02Å; T300-L350 HydrophobicContact CG2-CD1 4.34Å; T300-L350 HydrophobicContact CG2-CD2 3.78Å; T300-L350 HydrophobicContact CG2-CG 3.61Å; T300-H354 HydrophobicContact CG2-CB 3.58Å
301P96.9Very high97.4Very high10 Ų109.1 Ų9.17%0.0655%0.045CC..SBendtrans-65.4161.9179.1-22.434.5000114.3M276 T277 S306 F351 H354M276-P301 HydrophobicContact CE-CB 4Å; M276-P301 HydrophobicContact SD-CB 4.04Å; T277-P301 CarbonylContact O-C 3.57Å; T277-P301 VanDerWaalsContact O-CA 3.25Å; T277-P301 WeakPolarHBondContact O-CA 3.5Å; P301-S306 PolarHBondContact O-OG 2.75Å; P301-F351 HydrophobicContact CG-CD2 4.41Å; P301-F351 HydrophobicContact CG-CE2 3.57Å; P301-F351 HydrophobicContact CG-CZ 4.07Å; P301-H354 PolarHBondContact O-NE2 2.88Å; P301-H354 VanDerWaalsContact O-NE2 3.12Å
302D96.3Very high97.4Very high2 Ų27.9 Ų7.91%0.0114%0.039CC..  trans51.598.1-180-170.9-8.6000113.2K265 N270 T277 E304 R305 S306K265-D302 IonicContact NZ-OD1 3.16Å; K265-D302 IonicContact NZ-OD2 3.66Å; K265-D302 PolarHBondContact NZ-OD2 3.02Å; N270-D302 PolarHBondContact ND2-OD1 3.02Å; T277-D302 PolarHBondContact O-N 3.41Å; D302-E304 PolarHBondContact O-N 2.8Å; D302-E304 WeakPolarHBondContact OD1-CA 3.35Å; D302-E304 WeakPolarHBondContact OD1-CB 3.18Å; D302-E304 PolarHBondContact OD1-N 3Å; D302-R305 HydrophobicContact CB-CB 4.32Å; D302-R305 HydrophobicContact CB-CG 4.26Å; D302-R305 CarbonylContact O-C 3.52Å; D302-R305 PolarHBondContact O-N 2.77Å; D302-R305 VanDerWaalsContact OD2-CD 3.32Å; D302-R305 WeakPolarHBondContact OD2-CD 3.37Å; D302-R305 WeakPolarHBondContact OD2-CG 3.29Å; D302-R305 IonicContact OD2-CZ 2.86Å; D302-R305 IonicContact OD2-NE 2.96Å; D302-R305 PolarHBondContact OD2-NE 3.02Å; D302-R305 IonicContact OD2-NH2 2.73Å; D302-S306 WeakPolarHBondContact O-CB 3.5Å; D302-S306 PolarHBondContact O-N 2.93Å; D302-S306 PolarHBondContact O-OG 2.64Å; D302-S306 VanDerWaalsContact O-OG 3.1Å
303P96.8Very high97.5Very high0 Ų08.4 Ų8.40%04%0.039CC..THydrogen-bonded Turntrans-59.4-19.8177.423.2-33.5000113.9L262 R263 N270 T277 S280 T298 R305 F308 R376L262-P303 WeakPolarHBondContact O-CG 3.35Å; R263-P303 HydrophobicContact CG-CB 3.85Å; R263-P303 HydrophobicContact CG-CG 4.23Å; R263-P303 PolarHBondContact NE-O 2.84Å; R263-P303 PolarHBondContact NH2-O 2.9Å; N270-P303 WeakPolarHBondContact OD1-CD 3.35Å; T277-P303 HydrophobicContact CG2-CG 4.19Å; S280-P303 WeakPolarHBondContact OG-CB 3.37Å; S280-P303 WeakPolarHBondContact OG-CG 3.36Å; T298-P303 HydrophobicContact CG2-CB 4.41Å; P303-R305 VanDerWaalsContact C-N 3.3Å; P303-F308 HydrophobicContact CB-CE2 4.11Å; P303-F308 HydrophobicContact CB-CZ 4.12Å; P303-R376 PolarHBondContact O-NH2 3.2Å; P303-R376 VanDerWaalsContact O-NH2 3.1Å
304E94.6Very high97.4Very high88 Ų889.4 Ų9.441%0.4115%0.045SC..THydrogen-bonded Turntrans-69.7-29.7173.7-169.4-179.2-135.200111.7K265 D302 R376K265-E304 VanDerWaalsContact CE-OE2 3.25Å; K265-E304 WeakPolarHBondContact CE-OE2 3.47Å; K265-E304 IonicContact NZ-OE2 2.72Å; K265-E304 PolarHBondContact NZ-OE2 2.68Å; D302-E304 PolarHBondContact O-N 2.8Å; D302-E304 WeakPolarHBondContact OD1-CA 3.35Å; D302-E304 WeakPolarHBondContact OD1-CB 3.18Å; D302-E304 PolarHBondContact OD1-N 3Å; E304-R376 VanDerWaalsContact C-NH2 3.28Å; E304-R376 PolarHBondContact O-NH2 2.6Å
305R94.1Very high97Very high30 Ų3017.2 Ų17.211%0.1138%0.079CC..THydrogen-bonded Turntrans-102.2-7.1179.7-56.2175.9-157.9-166.30.6113.3E272 D302 P303 H354 I361 E362 L375E272-R305 IonicContact OE1-CZ 3.59Å; E272-R305 IonicContact OE1-NE 3.18Å; E272-R305 IonicContact OE1-NH2 3.54Å; E272-R305 PolarHBondContact OE1-NH2 2.76Å; D302-R305 HydrophobicContact CB-CB 4.32Å; D302-R305 HydrophobicContact CB-CG 4.26Å; D302-R305 CarbonylContact O-C 3.52Å; D302-R305 PolarHBondContact O-N 2.77Å; D302-R305 VanDerWaalsContact OD2-CD 3.32Å; D302-R305 WeakPolarHBondContact OD2-CD 3.37Å; D302-R305 WeakPolarHBondContact OD2-CG 3.29Å; D302-R305 IonicContact OD2-CZ 2.86Å; D302-R305 IonicContact OD2-NE 2.96Å; D302-R305 PolarHBondContact OD2-NE 3.02Å; D302-R305 IonicContact OD2-NH2 2.73Å; P303-R305 VanDerWaalsContact C-N 3.3Å; R305-H354 PolarHBondContact O-CE1 3.37Å; R305-I361 HydrophobicContact CB-CD1 4.35Å; R305-I361 HydrophobicContact CG-CD1 4.46Å; R305-E362 IonicContact CZ-OE1 2.87Å; R305-E362 IonicContact NH1-OE1 3.17Å; R305-E362 PolarHBondContact NH1-OE1 2.99Å; R305-E362 IonicContact NH2-OE1 3.58Å; R305-E362 PolarHBondContact NH2-OE1 3.05Å; R305-L375 WeakPolarHBondContact O-CD1 3.38Å
306S96.7Very high96.5Very high0 Ų022.5 Ų22.50%011%0.107CC..SBendtrans-105.9165.4-176.5-68.90000113.4T300 P301 D302 H354 R376T300-S306 WeakPolarHBondContact CB-OG 3.13Å; T300-S306 PolarHBondContact O-OG 2.86Å; T300-S306 VanDerWaalsContact OG1-CB 3.3Å; T300-S306 WeakPolarHBondContact OG1-CB 3.34Å; T300-S306 PolarHBondContact OG1-OG 3.02Å; P301-S306 PolarHBondContact O-OG 2.75Å; D302-S306 WeakPolarHBondContact O-CB 3.5Å; D302-S306 PolarHBondContact O-N 2.93Å; D302-S306 PolarHBondContact O-OG 2.64Å; D302-S306 VanDerWaalsContact O-OG 3.1Å; S306-H354 PolarHBondContact OG-CE1 2.65Å; S306-H354 VanDerWaalsContact OG-CE1 3.22Å; S306-R376 VanDerWaalsContact O-CZ 3.3Å; S306-R376 PolarHBondContact O-NH1 3.47Å; S306-R376 PolarHBondContact O-NH2 2.79Å
307V97.9Very high96.1Very high0 Ų023.4 Ų23.40%012%0.115CC..  trans-108.6130.5174.71780000110.3T298 K309 L375 L378 E379 E411T298-V307 WeakPolarHBondContact CA-O 3.31Å; V307-K309 HydrophobicContact CG1-CG 4.22Å; V307-K309 PolarHBondContact O-N 2.86Å; V307-K309 PolarHBondContact O-NZ 2.56Å; V307-L375 HydrophobicContact CG2-CB 3.69Å; V307-L375 HydrophobicContact CG2-CD2 3.68Å; V307-L375 HydrophobicContact CG2-CG 4.15Å; V307-L378 HydrophobicContact CG1-CD2 4.3Å; V307-L378 HydrophobicContact CG1-CG 4.33Å; V307-L378 HydrophobicContact CG2-CD2 4.38Å; V307-E379 HydrophobicContact CG1-CB 4.15Å; V307-E411 HydrophobicContact CG2-CG 4.39Å
308F98.7Very high95.6Very high0 Ų030.7 Ų30.70%014%0.142CC..  trans-74.8100.7169.3-80.9-79.5000110.4M259 L262 V282 Y296 T298 P303 E379M259-F308 HydrophobicContact CB-CD2 3.96Å; M259-F308 HydrophobicContact CB-CE2 3.77Å; M259-F308 HydrophobicContact CB-CZ 4.4Å; M259-F308 HydrophobicContact CE-CB 3.62Å; M259-F308 HydrophobicContact CE-CD1 4.31Å; M259-F308 HydrophobicContact CE-CD2 4.32Å; M259-F308 HydrophobicContact CE-CG 3.85Å; M259-F308 HydrophobicContact CG-CD1 4.3Å; M259-F308 HydrophobicContact CG-CD2 3.54Å; M259-F308 HydrophobicContact CG-CE1 4.39Å; M259-F308 HydrophobicContact CG-CE2 3.68Å; M259-F308 HydrophobicContact CG-CG 3.9Å; M259-F308 HydrophobicContact CG-CZ 4.11Å; M259-F308 HydrophobicContact SD-CB 3.77Å; M259-F308 HydrophobicContact SD-CD2 3.58Å; M259-F308 VanDerWaalsContact SD-CD2 3.58Å; M259-F308 HydrophobicContact SD-CE2 4.33Å; M259-F308 HydrophobicContact SD-CG 3.73Å; L262-F308 HydrophobicContact CB-CZ 4.46Å; L262-F308 HydrophobicContact CD1-CE1 4.36Å; L262-F308 HydrophobicContact CD1-CZ 4.09Å; V282-F308 HydrophobicContact CG2-CD1 4.37Å; V282-F308 HydrophobicContact CG2-CE1 3.9Å; V282-F308 HydrophobicContact CG2-CZ 4.29Å; Y296-F308 HydrophobicContact CD1-CB 4.45Å; T298-F308 HydrophobicContact CG2-CD1 4.03Å; T298-F308 HydrophobicContact CG2-CD2 4.4Å; T298-F308 HydrophobicContact CG2-CE1 3.88Å; T298-F308 HydrophobicContact CG2-CE2 4.25Å; T298-F308 HydrophobicContact CG2-CG 4.28Å; T298-F308 HydrophobicContact CG2-CZ 3.99Å; P303-F308 HydrophobicContact CB-CE2 4.11Å; P303-F308 HydrophobicContact CB-CZ 4.12Å; F308-E379 HydrophobicContact CB-CG 4.43Å; F308-E379 WeakPolarHBondContact CB-OE2 3.35Å; F308-E379 WeakPolarHBondContact CD2-OE2 3.4Å; F308-E379 PolarHBondContact N-OE2 2.9Å
309K98.4Very high95.3Very high0 Ų036.6 Ų36.60%017%0.169CC..EExtended strand (participates in β ladder)trans-90.5127.3-176.5-67.8160.2-82.1-77.90110.4Y296 F297 T298 V307 F404 C407 V408 E411Y296-K309 VanDerWaalsContact CA-O 3.29Å; Y296-K309 WeakPolarHBondContact CA-O 3.3Å; F297-K309 PolarHBondContact N-O 3.49Å; F297-K309 PolarHBondContact O-N 2.72Å; T298-K309 WeakPolarHBondContact O-CE 3.35Å; T298-K309 PolarHBondContact O-NZ 2.92Å; V307-K309 HydrophobicContact CG1-CG 4.22Å; V307-K309 PolarHBondContact O-N 2.86Å; V307-K309 PolarHBondContact O-NZ 2.56Å; K309-F404 HydrophobicContact CB-CD2 3.79Å; K309-F404 HydrophobicContact CB-CE2 3.53Å; K309-F404 HydrophobicContact CB-CZ 4.2Å; K309-F404 HydrophobicContact CD-CE2 4.39Å; K309-F404 HydrophobicContact CD-CZ 4.22Å; K309-C407 HydrophobicContact CB-CB 4.2Å; K309-C407 HydrophobicContact CG-CB 4.04Å; K309-V408 HydrophobicContact CD-CB 4.38Å; K309-V408 HydrophobicContact CD-CG2 3.48Å; K309-V408 VanDerWaalsContact CD-CG2 3.48Å; K309-E411 IonicContact NZ-OE1 3.26Å; K309-E411 IonicContact NZ-OE2 2.68Å; K309-E411 PolarHBondContact NZ-OE2 3.28Å
310P98.4Very high95.3Very high1 Ų136.9 Ų36.91%0.00617%0.171CC..EExtended strand (participates in β ladder)trans-77.9147.4-175.130.5-34.3000112.9V294 H295 Y296 A382 M386 L403 F404V294-P310 HydrophobicContact CG1-CB 3.99Å; H295-P310 CarbonylContact O-C 3.48Å; Y296-P310 HydrophobicContact CD1-CB 3.79Å; Y296-P310 HydrophobicContact CE1-CB 3.7Å; Y296-P310 HydrophobicContact CE1-CG 4.46Å; P310-A382 HydrophobicContact CG-CB 4.18Å; P310-M386 HydrophobicContact CB-CG 3.63Å; P310-M386 HydrophobicContact CB-SD 3.68Å; P310-M386 HydrophobicContact CG-CG 4.03Å; P310-M386 HydrophobicContact CG-SD 4.11Å; P310-L403 HydrophobicContact CB-CD2 4.04Å; P310-L403 HydrophobicContact CB-CG 4.48Å; P310-L403 HydrophobicContact CG-CD1 4.1Å; P310-L403 HydrophobicContact CG-CD2 4.06Å; P310-L403 HydrophobicContact CG-CG 4Å; P310-F404 WeakPolarHBondContact O-CA 3.45Å
311F98.4Very high95.2Very high9 Ų943.4 Ų43.44%0.03920%0.199CC..EExtended strand (participates in β ladder)trans-133.5139.4170.7179.8-87.2000108.8H39 V68 H295 F313 A317 L320 F404H39-F311 HydrophobicContact CB-CE2 4.2Å; H39-F311 HydrophobicContact CB-CZ 4.3Å; H39-F311 AromaticContact CD2-CZ 3.71Å; H39-F311 AromaticContact CG-CZ 3.98Å; V68-F311 HydrophobicContact CB-CD1 3.92Å; V68-F311 HydrophobicContact CB-CE1 3.82Å; V68-F311 HydrophobicContact CB-CG 4.4Å; V68-F311 HydrophobicContact CB-CZ 4.2Å; V68-F311 HydrophobicContact CG1-CD1 3.68Å; V68-F311 HydrophobicContact CG1-CE1 3.87Å; V68-F311 HydrophobicContact CG1-CG 4.41Å; V68-F311 HydrophobicContact CG2-CD1 4.14Å; V68-F311 HydrophobicContact CG2-CD2 4.31Å; V68-F311 HydrophobicContact CG2-CE1 4.37Å; V68-F311 HydrophobicContact CG2-CG 4.11Å; H295-F311 PolarHBondContact N-O 2.73Å; H295-F311 WeakPolarHBondContact O-CA 3.47Å; H295-F311 WeakPolarHBondContact O-CB 2.96Å; H295-F311 PolarHBondContact O-N 2.71Å; F311-F313 HydrophobicContact CD1-CE2 4.49Å; F311-F313 AromaticContact CE1-CD1 3.83Å; F311-F313 HydrophobicContact CE1-CD1 3.83Å; F311-F313 HydrophobicContact CE1-CD2 4.05Å; F311-F313 AromaticContact CE1-CE1 3.82Å; F311-F313 HydrophobicContact CE1-CE1 3.82Å; F311-F313 HydrophobicContact CE1-CE2 4.04Å; F311-F313 AromaticContact CE1-CG 3.95Å; F311-F313 HydrophobicContact CE1-CG 3.95Å; F311-F313 AromaticContact CE1-CZ 3.93Å; F311-F313 HydrophobicContact CE1-CZ 3.93Å; F311-F313 HydrophobicContact CZ-CD1 4.34Å; F311-F313 HydrophobicContact CZ-CE1 4.38Å; F311-A317 HydrophobicContact CZ-CB 4.4Å; F311-L320 HydrophobicContact CD2-CD1 4.45Å; F311-F404 HydrophobicContact CB-CD2 4.32Å; F311-F404 HydrophobicContact CD2-CB 4.28Å
312V97.6Very high95.2Very high3 Ų344.7 Ų44.72%0.01820%0.204CC..  trans-133.3134.9175.3-179.30000107.9P292 V294 V314 M386 I389 V394 L403P292-V312 HydrophobicContact CB-CG1 4.06Å; V294-V312 HydrophobicContact CB-CG2 4.44Å; V294-V312 HydrophobicContact CG1-CG2 4.31Å; V294-V312 HydrophobicContact CG2-CG2 3.95Å; V312-V314 HydrophobicContact CG1-CG1 4.25Å; V312-V314 PolarHBondContact O-N 2.96Å; V312-V314 VanDerWaalsContact O-N 3.1Å; V312-M386 HydrophobicContact CG2-SD 4.15Å; V312-I389 HydrophobicContact CG2-CD1 4.19Å; V312-V394 HydrophobicContact CG1-CG2 4.14Å; V312-L403 HydrophobicContact CG2-CD2 4.04Å
313F97.2Very high95.2Very high33 Ų3344.6 Ų44.615%0.14520%0.204CC..  trans-67.9110173.8-71.8-82.9000110.1A66 V68 A82 N83 E84 H295 F311A66-F313 HydrophobicContact CB-CD1 4.37Å; A66-F313 HydrophobicContact CB-CE1 4.22Å; V68-F313 HydrophobicContact CB-CZ 4.26Å; V68-F313 HydrophobicContact CG1-CE2 4.08Å; V68-F313 HydrophobicContact CG1-CZ 3.75Å; A82-F313 HydrophobicContact CB-CE2 4.29Å; A82-F313 WeakPolarHBondContact O-CZ 3.19Å; N83-F313 WeakPolarHBondContact O-CE2 3.49Å; E84-F313 HydrophobicContact CB-CB 4.47Å; E84-F313 HydrophobicContact CB-CD1 3.93Å; E84-F313 HydrophobicContact CB-CE1 4.35Å; E84-F313 HydrophobicContact CB-CG 4.15Å; H295-F313 AromaticContact CD2-CD2 3.9Å; H295-F313 AromaticContact CD2-CE2 3.69Å; H295-F313 AromaticContact NE2-CD2 3.74Å; H295-F313 AromaticContact NE2-CE2 3.57Å; F311-F313 HydrophobicContact CD1-CE2 4.49Å; F311-F313 AromaticContact CE1-CD1 3.83Å; F311-F313 HydrophobicContact CE1-CD1 3.83Å; F311-F313 HydrophobicContact CE1-CD2 4.05Å; F311-F313 AromaticContact CE1-CE1 3.82Å; F311-F313 HydrophobicContact CE1-CE1 3.82Å; F311-F313 HydrophobicContact CE1-CE2 4.04Å; F311-F313 AromaticContact CE1-CG 3.95Å; F311-F313 HydrophobicContact CE1-CG 3.95Å; F311-F313 AromaticContact CE1-CZ 3.93Å; F311-F313 HydrophobicContact CE1-CZ 3.93Å; F311-F313 HydrophobicContact CZ-CD1 4.34Å; F311-F313 HydrophobicContact CZ-CE1 4.38Å
314V95.4Very high95.2Very high20 Ų2046 Ų4612%0.12121%0.213CC..  trans-129.4156173.1-66.20000110V312 N316 A317 V394 P397 V401V312-V314 HydrophobicContact CG1-CG1 4.25Å; V312-V314 PolarHBondContact O-N 2.96Å; V312-V314 VanDerWaalsContact O-N 3.1Å; V314-N316 PolarHBondContact O-N 2.94Å; V314-A317 HydrophobicContact CG2-CB 4.36Å; V314-A317 WeakPolarHBondContact O-CB 3.34Å; V314-A317 PolarHBondContact O-N 3.04Å; V314-V394 HydrophobicContact CG1-CG1 4.18Å; V314-V394 HydrophobicContact CG1-CG2 4.41Å; V314-P397 HydrophobicContact CB-CB 4.2Å; V314-P397 HydrophobicContact CG1-CB 4.3Å; V314-V401 HydrophobicContact CG2-CG1 4.02Å
315K90.3Very high95.3Very high164 Ų16442.6 Ų42.671%0.71320%0.2SC*.THydrogen-bonded Turntrans-57.7137.5175.1-167.6-179.7179.9178.60109.6A317K315-A317 VanDerWaalsContact C-N 3.27Å; K315-A317 PolarHBondContact O-N 2.95Å
316N89.1Confident95.4Very high112 Ų11244.3 Ų44.360%0.59922%0.215SC*.THydrogen-bonded Turntrans63.723.6-179.9-43.5-49.2000115.1V314 R318V314-N316 PolarHBondContact O-N 2.94Å; N316-R318 PolarHBondContact O-N 3.38Å
317A90.4Very high95.3Very high19 Ų1949.8 Ų49.816%0.15725%0.253CS..PPolyproline II helixtrans-50.2130.8169.400000110.6F311 V314 K315F311-A317 HydrophobicContact CZ-CB 4.4Å; V314-A317 HydrophobicContact CG2-CB 4.36Å; V314-A317 WeakPolarHBondContact O-CB 3.34Å; V314-A317 PolarHBondContact O-N 3.04Å; K315-A317 VanDerWaalsContact C-N 3.27Å; K315-A317 PolarHBondContact O-N 2.95Å
318R89.1Confident95.1Very high153 Ų15352.8 Ų52.858%0.57727%0.266SS*.PPolyproline II helixtrans-85.9167.2-172.2-62.8-163.8-177.7165.3-5.3112.2N316 V401 N402N316-R318 PolarHBondContact O-N 3.38Å; R318-V401 PolarHBondContact N-O 3.47Å; R318-N402 VanDerWaalsContact CD-OD1 3.27Å; R318-N402 WeakPolarHBondContact CD-OD1 2.91Å; R318-N402 PolarHBondContact NH1-OD1 2.96Å
319E91.4Very high94.9Very high123 Ų12354.4 Ų54.458%0.57528%0.283SS*.PPolyproline II helixtrans-65136.9170.2-174.8-179.3-149.500110.8K321E319-K321 HydrophobicContact CB-CG 4.45Å; E319-K321 HydrophobicContact CG-CG 4.14Å; E319-K321 PolarHBondContact O-N 3.06Å; E319-K321 WeakPolarHBondContact OE2-CE 3.26Å
320L96.7Very high94.7Very high6 Ų660 Ų603%0.03132%0.319CS..  trans-9173.1-175.6-52.5-177.6000110.6V37 H39 V68 F311 E322 T323 S324 F404V37-L320 HydrophobicContact CG1-CD1 3.93Å; H39-L320 HydrophobicContact CB-CD1 4.17Å; H39-L320 HydrophobicContact CB-CG 4.19Å; V68-L320 HydrophobicContact CG2-CD1 4.45Å; F311-L320 HydrophobicContact CD2-CD1 4.45Å; L320-E322 PolarHBondContact O-N 2.79Å; L320-T323 PolarHBondContact O-N 2.64Å; L320-T323 PolarHBondContact O-OG1 3.43Å; L320-S324 PolarHBondContact O-N 2.66Å; L320-S324 PolarHBondContact O-OG 2.94Å; L320-F404 HydrophobicContact CB-CD1 4.42Å; L320-F404 HydrophobicContact CD1-CD1 3.95Å; L320-F404 HydrophobicContact CD1-CE1 4.25Å; L320-F404 HydrophobicContact CD1-CG 4.29Å; L320-F404 HydrophobicContact CD2-CB 4.06Å; L320-F404 HydrophobicContact CD2-CD1 3.92Å; L320-F404 HydrophobicContact CD2-CG 4.27Å; L320-F404 HydrophobicContact CG-CD1 4.31Å
321K94.8Very high94.5Very high138 Ų13865.2 Ų65.260%0.635%0.347SS*.G310 helixtrans-66.3-33.7-167.1-64.8-176.2179.3-175.60114E319 T323 S324E319-K321 HydrophobicContact CB-CG 4.45Å; E319-K321 HydrophobicContact CG-CG 4.14Å; E319-K321 PolarHBondContact O-N 3.06Å; E319-K321 WeakPolarHBondContact OE2-CE 3.26Å; K321-T323 PolarHBondContact O-N 3.17Å; K321-S324 PolarHBondContact O-N 2.71Å
322E96.4Very high94.5Very high37 Ų3765.6 Ų65.617%0.17335%0.349CS..G310 helixtrans-69-19.3-177.3-62.985.317400113.8L320 H348 P349 L350 S405 V408 Q409L320-E322 PolarHBondContact O-N 2.79Å; E322-H348 PolarHBondContact O-ND1 2.75Å; E322-P349 WeakPolarHBondContact O-CD 3.45Å; E322-L350 WeakPolarHBondContact O-CB 3.06Å; E322-L350 PolarHBondContact O-N 3.14Å; E322-L350 VanDerWaalsContact O-N 3.11Å; E322-S405 PolarHBondContact OE2-OG 2.98Å; E322-V408 HydrophobicContact CB-CB 4.37Å; E322-V408 HydrophobicContact CB-CG1 3.57Å; E322-V408 HydrophobicContact CG-CG1 4.02Å; E322-Q409 PolarHBondContact OE1-NE2 3.07Å
323T97.6Very high94.4Very high0 Ų065.6 Ų65.60%035%0.35CS..G310 helixtrans-115.813.4179.650.90000112.9E36 V37 L320 K321 L350 F404 V408E36-T323 WeakPolarHBondContact CA-O 3.4Å; E36-T323 VanDerWaalsContact CB-O 3.3Å; E36-T323 WeakPolarHBondContact CB-O 3.28Å; V37-T323 PolarHBondContact N-O 2.81Å; V37-T323 WeakPolarHBondContact O-CB 3.32Å; V37-T323 PolarHBondContact O-OG1 3.2Å; L320-T323 PolarHBondContact O-N 2.64Å; L320-T323 PolarHBondContact O-OG1 3.43Å; K321-T323 PolarHBondContact O-N 3.17Å; T323-L350 HydrophobicContact CG2-CB 4.41Å; T323-L350 HydrophobicContact CG2-CD2 3.8Å; T323-F404 HydrophobicContact CG2-CE1 3.84Å; T323-F404 HydrophobicContact CG2-CZ 4.24Å; T323-V408 HydrophobicContact CG2-CG2 4.34Å
324S96.8Very high94.3Very high29 Ų2964.3 Ų64.320%0.20335%0.345CS..PPolyproline II helixtrans-101.9128.1174.9-60.80000110.3L320 K321 H348L320-S324 PolarHBondContact O-N 2.66Å; L320-S324 PolarHBondContact O-OG 2.94Å; K321-S324 PolarHBondContact O-N 2.71Å; S324-H348 VanDerWaalsContact O-CB 3.27Å; S324-H348 WeakPolarHBondContact O-CB 3.45Å
325S96.9Very high94.3Very high17 Ų1766.3 Ų66.312%0.11935%0.352CS..PPolyproline II helixtrans-79.3159.8178.1-67.30000111.9E36 A73 R346E36-S325 WeakPolarHBondContact CG-OG 3.42Å; E36-S325 WeakPolarHBondContact OE1-CA 3.43Å; E36-S325 WeakPolarHBondContact OE1-CB 3.09Å; E36-S325 PolarHBondContact OE1-N 3.45Å; A73-S325 WeakPolarHBondContact CB-OG 3.48Å; S325-R346 WeakPolarHBondContact CB-O 3.24Å; S325-R346 PolarHBondContact OG-O 3.3Å
326P95.6Very high94.5Very high67 Ų6762.7 Ų62.744%0.43534%0.336SS..PPolyproline II helixtrans-58.6140.3173-22.833.7000112.3F328P326-F328 HydrophobicContact CB-CE2 4.32Å; P326-F328 HydrophobicContact CB-CZ 4.06Å; P326-F328 VanDerWaalsContact O-CE2 3.31Å; P326-F328 WeakPolarHBondContact O-CE2 2.99Å
327S93.5Very high94.7Very high115 Ų11564.6 Ų64.680%0.80434%0.339SS*.PPolyproline II helixtrans-90.7133.5172.4-173.60000111G329S327-G329 PolarHBondContact OG-N 2.64Å
328F95.1Very high94.8Very high62 Ų6268.1 Ų68.127%0.27236%0.36SS..  trans-103.6-1.5176-56.6-82.7000112.8P326 D331 D332 P344 R346P326-F328 HydrophobicContact CB-CE2 4.32Å; P326-F328 HydrophobicContact CB-CZ 4.06Å; P326-F328 VanDerWaalsContact O-CE2 3.31Å; P326-F328 WeakPolarHBondContact O-CE2 2.99Å; F328-D331 WeakPolarHBondContact O-CA 3.36Å; F328-D331 WeakPolarHBondContact O-CB 3.4Å; F328-D331 PolarHBondContact O-N 3.14Å; F328-D332 HydrophobicContact CB-CB 3.87Å; F328-D332 PolarHBondContact O-N 3.03Å; F328-P344 HydrophobicContact CD1-CB 4.18Å; F328-P344 HydrophobicContact CD2-CB 4.42Å; F328-P344 HydrophobicContact CD2-CG 4.03Å; F328-P344 HydrophobicContact CE1-CB 3.64Å; F328-P344 HydrophobicContact CE1-CG 4.29Å; F328-P344 HydrophobicContact CE2-CB 3.93Å; F328-P344 HydrophobicContact CE2-CG 3.8Å; F328-P344 HydrophobicContact CG-CG 4.4Å; F328-P344 HydrophobicContact CZ-CB 3.52Å; F328-P344 HydrophobicContact CZ-CG 3.95Å; F328-R346 HydrophobicContact CE2-CG 4.17Å
329G94Very high95Very high34 Ų3462.7 Ų62.735%0.35134%0.339SS..G310 helixtrans52.3-137.217700000113.3S327 D331 D332S327-G329 PolarHBondContact OG-N 2.64Å; G329-D331 PolarHBondContact O-N 2.77Å; G329-D331 VanDerWaalsContact O-N 3.13Å; G329-D332 WeakPolarHBondContact O-CB 3.41Å; G329-D332 PolarHBondContact O-N 2.88Å; G329-D332 VanDerWaalsContact O-N 3.17Å
330P93.9Very high95.2Very high117 Ų11757.5 Ų57.576%0.7632%0.315SS*.G310 helixtrans-61.5-17.3176-22.534000114.4D332P330-D332 VanDerWaalsContact C-N 3.32Å
331D95.2Very high95.1Very high112 Ų11262.6 Ų62.660%0.59934%0.339SS*.G310 helixtrans-83.4-8.5179.6-79.7-51.5000114F328 G329 K336F328-D331 WeakPolarHBondContact O-CA 3.36Å; F328-D331 WeakPolarHBondContact O-CB 3.4Å; F328-D331 PolarHBondContact O-N 3.14Å; G329-D331 PolarHBondContact O-N 2.77Å; G329-D331 VanDerWaalsContact O-N 3.13Å; D331-K336 VanDerWaalsContact CA-NZ 3.3Å; D331-K336 WeakPolarHBondContact O-CE 3.14Å; D331-K336 PolarHBondContact O-NZ 3.38Å; D331-K336 WeakPolarHBondContact OD1-CE 3.19Å; D331-K336 IonicContact OD1-NZ 2.75Å; D331-K336 PolarHBondContact OD1-NZ 2.9Å
332D96.7Very high95Very high16 Ų1659.5 Ų59.59%0.08633%0.334CS..SBendtrans-58.7132.5178.9-161.2-58.1000111.1F328 G329 P330 V334 K335 K336 R346F328-D332 HydrophobicContact CB-CB 3.87Å; F328-D332 PolarHBondContact O-N 3.03Å; G329-D332 WeakPolarHBondContact O-CB 3.41Å; G329-D332 PolarHBondContact O-N 2.88Å; G329-D332 VanDerWaalsContact O-N 3.17Å; P330-D332 VanDerWaalsContact C-N 3.32Å; D332-V334 HydrophobicContact CB-CG1 4.22Å; D332-V334 PolarHBondContact O-N 3.41Å; D332-V334 VanDerWaalsContact O-N 3.14Å; D332-V334 VanDerWaalsContact OD1-CG1 3.29Å; D332-V334 WeakPolarHBondContact OD1-CG1 3.38Å; D332-V334 PolarHBondContact OD1-N 3.07Å; D332-K335 HydrophobicContact CB-CG 4.2Å; D332-K335 WeakPolarHBondContact O-CA 3.28Å; D332-K335 WeakPolarHBondContact O-CB 3.17Å; D332-K335 PolarHBondContact O-N 3.01Å; D332-K336 PolarHBondContact O-N 3.33Å; D332-R346 VanDerWaalsContact CG-NH2 3.32Å; D332-R346 IonicContact OD1-CZ 3.54Å; D332-R346 IonicContact OD1-NH1 2.77Å; D332-R346 IonicContact OD1-NH2 3.17Å; D332-R346 PolarHBondContact OD1-NH2 3.3Å; D332-R346 IonicContact OD2-CZ 3.73Å; D332-R346 IonicContact OD2-NH1 2.84Å; D332-R346 PolarHBondContact OD2-NH1 2.91Å; D332-R346 IonicContact OD2-NH2 2.94Å; D332-R346 PolarHBondContact OD2-NH2 2.76Å; D332-R346 VanDerWaalsContact OD2-NH2 3.14Å
333P96.1Very high94.9Very high4 Ų462 Ų623%0.02635%0.345CS..THydrogen-bonded Turntrans-56.2-28177.6-23.830.4000114.7K335 K336 F340 S342 P344P333-K335 PolarHBondContact O-N 3.4Å; P333-K336 PolarHBondContact O-N 2.73Å; P333-F340 HydrophobicContact CB-CD1 4.21Å; P333-F340 PolarHBondContact O-N 2.91Å; P333-S342 VanDerWaalsContact CB-O 3.29Å; P333-S342 WeakPolarHBondContact CB-O 3.44Å; P333-S342 WeakPolarHBondContact CG-O 3.13Å; P333-P344 HydrophobicContact CG-CG 4.25Å
334V95.6Very high94.8Very high6 Ų663.7 Ų63.74%0.03636%0.355CS..THydrogen-bonded Turntrans-67.6-16.6174.4800000112.2T54 Y55 W74 D332 R339 F340T54-V334 HydrophobicContact CG2-CG2 3.84Å; Y55-V334 HydrophobicContact CD1-CG2 4.38Å; Y55-V334 HydrophobicContact CE1-CG2 3.87Å; W74-V334 HydrophobicContact CE3-CB 4.34Å; W74-V334 HydrophobicContact CE3-CG2 3.78Å; W74-V334 HydrophobicContact CZ3-CG2 3.85Å; D332-V334 HydrophobicContact CB-CG1 4.22Å; D332-V334 PolarHBondContact O-N 3.41Å; D332-V334 VanDerWaalsContact O-N 3.14Å; D332-V334 VanDerWaalsContact OD1-CG1 3.29Å; D332-V334 WeakPolarHBondContact OD1-CG1 3.38Å; D332-V334 PolarHBondContact OD1-N 3.07Å; V334-R339 WeakPolarHBondContact O-CD 3.29Å; V334-R339 PolarHBondContact O-NE 3.06Å; V334-R339 VanDerWaalsContact O-NE 3.16Å; V334-R339 PolarHBondContact O-NH1 3.03Å; V334-F340 HydrophobicContact CB-CE1 4.01Å; V334-F340 HydrophobicContact CB-CZ 4.45Å; V334-F340 HydrophobicContact CG2-CE1 4.09Å; V334-F340 HydrophobicContact CG2-CZ 4.04Å
335K95.2Very high94.8Very high62 Ų6267.6 Ų67.627%0.2737%0.374SS..THydrogen-bonded Turntrans-101.2-16.1-180-58.9-55.6-176.9-1760113.8E52 C53 D332 P333 R339E52-K335 VanDerWaalsContact OE1-CD 3.31Å; E52-K335 WeakPolarHBondContact OE1-CD 3.16Å; E52-K335 VanDerWaalsContact OE1-CE 3.24Å; E52-K335 WeakPolarHBondContact OE1-CE 3.16Å; E52-K335 IonicContact OE1-NZ 3.7Å; E52-K335 PolarHBondContact OE1-NZ 2.73Å; C53-K335 PolarHBondContact O-NZ 3.25Å; D332-K335 HydrophobicContact CB-CG 4.2Å; D332-K335 WeakPolarHBondContact O-CA 3.28Å; D332-K335 WeakPolarHBondContact O-CB 3.17Å; D332-K335 PolarHBondContact O-N 3.01Å; P333-K335 PolarHBondContact O-N 3.4Å; K335-R339 PolarHBondContact O-NH1 2.86Å
336K94.9Very high94.8Very high88 Ų8867.2 Ų67.238%0.38337%0.37SS..SBendtrans-89.4146.1176.6-67.9174.1173.2159.30112.2D331 D332 P333 P338 R339D331-K336 VanDerWaalsContact CA-NZ 3.3Å; D331-K336 WeakPolarHBondContact O-CE 3.14Å; D331-K336 PolarHBondContact O-NZ 3.38Å; D331-K336 WeakPolarHBondContact OD1-CE 3.19Å; D331-K336 IonicContact OD1-NZ 2.75Å; D331-K336 PolarHBondContact OD1-NZ 2.9Å; D332-K336 PolarHBondContact O-N 3.33Å; P333-K336 PolarHBondContact O-N 2.73Å; K336-P338 CarbonylContact C-O 3.41Å; K336-P338 CarbonylContact O-C 3.58Å; K336-R339 VanDerWaalsContact O-CA 3.31Å; K336-R339 WeakPolarHBondContact O-CA 3.22Å; K336-R339 VanDerWaalsContact O-CD 3.31Å; K336-R339 WeakPolarHBondContact O-CD 3.34Å; K336-R339 PolarHBondContact O-N 2.93Å; K336-R339 PolarHBondContact O-NH1 2.91Å
337K92.9Very high94.9Very high152 Ų15267 Ų6766%0.66136%0.362SS*.SBendtrans-116.8130.2172.2-69.6-166.1174-163.50109.4E104E104-K337 WeakPolarHBondContact OE2-CE 3.45Å; E104-K337 IonicContact OE2-NZ 2.79Å; E104-K337 PolarHBondContact OE2-NZ 3.3Å
338P92.6Very high95Very high92 Ų9261.6 Ų61.660%0.59732%0.324SS*.SBendcis-61150.3-727-33.5000112.2K336 Q341K336-P338 CarbonylContact C-O 3.41Å; K336-P338 CarbonylContact O-C 3.58Å; P338-Q341 HydrophobicContact CB-CG 4.43Å; P338-Q341 HydrophobicContact CG-CG 3.84Å; P338-Q341 WeakPolarHBondContact O-CG 3.47Å
339R94.3Very high95.1Very high39 Ų3962.2 Ų62.215%0.14733%0.334CS..THydrogen-bonded Turntrans-70.4157.9-176.5-60.7-81.7179.2-139.217.8110.9E104 V334 K335 K336 Q341E104-R339 IonicContact OE1-CZ 2.64Å; E104-R339 IonicContact OE1-NE 2.66Å; E104-R339 PolarHBondContact OE1-NE 3.01Å; E104-R339 IonicContact OE1-NH2 3.93Å; E104-R339 IonicContact OE2-NH2 2.71Å; V334-R339 WeakPolarHBondContact O-CD 3.29Å; V334-R339 PolarHBondContact O-NE 3.06Å; V334-R339 VanDerWaalsContact O-NE 3.16Å; V334-R339 PolarHBondContact O-NH1 3.03Å; K335-R339 PolarHBondContact O-NH1 2.86Å; K336-R339 VanDerWaalsContact O-CA 3.31Å; K336-R339 WeakPolarHBondContact O-CA 3.22Å; K336-R339 VanDerWaalsContact O-CD 3.31Å; K336-R339 WeakPolarHBondContact O-CD 3.34Å; K336-R339 PolarHBondContact O-N 2.93Å; K336-R339 PolarHBondContact O-NH1 2.91Å; R339-Q341 VanDerWaalsContact C-N 3.25Å; R339-Q341 PolarHBondContact O-N 2.8Å; R339-Q341 VanDerWaalsContact O-N 3.07Å; R339-Q341 PolarHBondContact O-NE2 2.76Å
340F94.4Very high95.3Very high14 Ų1460.6 Ų60.66%0.06132%0.318CS..THydrogen-bonded Turntrans53.935165.9-46.7-57.4000115.2Y55 W74 M143 E144 D145 Q146 P333 V334 S342Y55-F340 HydrophobicContact CE1-CE2 4.49Å; Y55-F340 HydrophobicContact CE1-CZ 4.23Å; Y55-F340 WeakPolarHBondContact OH-CE2 3.37Å; Y55-F340 WeakPolarHBondContact OH-CZ 3.13Å; W74-F340 AromaticContact CE3-CE1 3.9Å; W74-F340 HydrophobicContact CE3-CE1 3.9Å; W74-F340 AromaticContact CE3-CZ 3.88Å; W74-F340 HydrophobicContact CE3-CZ 3.88Å; W74-F340 HydrophobicContact CH2-CZ 4.28Å; W74-F340 HydrophobicContact CZ3-CE1 4.14Å; W74-F340 AromaticContact CZ3-CZ 3.62Å; W74-F340 HydrophobicContact CZ3-CZ 3.62Å; M143-F340 WeakPolarHBondContact O-CE2 3.31Å; E144-F340 HydrophobicContact CB-CD1 4.37Å; E144-F340 HydrophobicContact CB-CE1 4.35Å; E144-F340 HydrophobicContact CG-CD1 3.66Å; E144-F340 HydrophobicContact CG-CE1 3.9Å; D145-F340 VanDerWaalsContact O-CD2 3.23Å; D145-F340 WeakPolarHBondContact O-CD2 3.5Å; Q146-F340 WeakPolarHBondContact CG-O 3.24Å; P333-F340 HydrophobicContact CB-CD1 4.21Å; P333-F340 PolarHBondContact O-N 2.91Å; V334-F340 HydrophobicContact CB-CE1 4.01Å; V334-F340 HydrophobicContact CB-CZ 4.45Å; V334-F340 HydrophobicContact CG2-CE1 4.09Å; V334-F340 HydrophobicContact CG2-CZ 4.04Å; F340-S342 PolarHBondContact O-N 3.14Å
341Q94.8Very high95.4Very high114 Ų11455.5 Ų55.553%0.53328%0.283SS..SBendtrans-72.1-8.5174-61.5-57.9-69.500113.3P338 R339P338-Q341 HydrophobicContact CB-CG 4.43Å; P338-Q341 HydrophobicContact CG-CG 3.84Å; P338-Q341 WeakPolarHBondContact O-CG 3.47Å; R339-Q341 VanDerWaalsContact C-N 3.25Å; R339-Q341 PolarHBondContact O-N 2.8Å; R339-Q341 VanDerWaalsContact O-N 3.07Å; R339-Q341 PolarHBondContact O-NE2 2.76Å
342S93.6Very high95.5Very high72 Ų7253.2 Ų53.250%0.50327%0.273SS..SBendtrans-151.5155.4175.655.70000108.4P333 F340P333-S342 VanDerWaalsContact CB-O 3.29Å; P333-S342 WeakPolarHBondContact CB-O 3.44Å; P333-S342 WeakPolarHBondContact CG-O 3.13Å; F340-S342 PolarHBondContact O-N 3.14Å
343K93.7Very high95.5Very high91 Ų9158 Ų5840%0.39629%0.294SS..  trans-124.9101.7176.5-170.4169.9-174.1171.90109.3D32 E144D32-K343 IonicContact OD1-NZ 2.83Å; D32-K343 PolarHBondContact OD1-NZ 3.33Å; D32-K343 WeakPolarHBondContact OD2-CE 3.47Å; D32-K343 IonicContact OD2-NZ 2.98Å; D32-K343 PolarHBondContact OD2-NZ 3.18Å; E144-K343 HydrophobicContact CG-CG 4.41Å
344P95.4Very high95.5Very high34 Ų3458.1 Ų58.122%0.22129%0.294CS..  trans-72.7160.6-17931.1-36.5000111.3F328 P333 R346F328-P344 HydrophobicContact CD1-CB 4.18Å; F328-P344 HydrophobicContact CD2-CB 4.42Å; F328-P344 HydrophobicContact CD2-CG 4.03Å; F328-P344 HydrophobicContact CE1-CB 3.64Å; F328-P344 HydrophobicContact CE1-CG 4.29Å; F328-P344 HydrophobicContact CE2-CB 3.93Å; F328-P344 HydrophobicContact CE2-CG 3.8Å; F328-P344 HydrophobicContact CG-CG 4.4Å; F328-P344 HydrophobicContact CZ-CB 3.52Å; F328-P344 HydrophobicContact CZ-CG 3.95Å; P333-P344 HydrophobicContact CG-CG 4.25Å; P344-R346 HydrophobicContact CG-CG 4.37Å; P344-R346 PolarHBondContact O-N 2.92Å
345D96Very high95.5Very high111 Ų11162.1 Ų62.159%0.59431%0.312SS*.  trans-74.3112.9172-174.5-3.1000110.1K347D345-K347 VanDerWaalsContact OD1-CB 3.32Å; D345-K347 WeakPolarHBondContact OD1-CB 3.41Å; D345-K347 WeakPolarHBondContact OD1-CG 3.47Å; D345-K347 PolarHBondContact OD1-N 3.12Å
346R96.9Very high95.5Very high10 Ų1063.2 Ų63.24%0.03832%0.324CS..  trans-101.28.6-178.1-57.8-172179.6-91.80.9113.2V34 A73 E144 S325 F328 D332 P344 H348V34-R346 HydrophobicContact CB-CB 4.39Å; V34-R346 HydrophobicContact CG2-CB 4.38Å; A73-R346 HydrophobicContact CB-CB 3.71Å; A73-R346 HydrophobicContact CB-CG 4.29Å; A73-R346 PolarHBondContact O-NH1 3.19Å; E144-R346 IonicContact OE1-CZ 3.05Å; E144-R346 IonicContact OE1-NE 3.74Å; E144-R346 PolarHBondContact OE1-NE 2.88Å; E144-R346 IonicContact OE1-NH2 2.79Å; E144-R346 PolarHBondContact OE1-NH2 3.17Å; E144-R346 IonicContact OE2-NE 3.82Å; E144-R346 PolarHBondContact OE2-NE 2.87Å; S325-R346 WeakPolarHBondContact CB-O 3.24Å; S325-R346 PolarHBondContact OG-O 3.3Å; F328-R346 HydrophobicContact CE2-CG 4.17Å; D332-R346 VanDerWaalsContact CG-NH2 3.32Å; D332-R346 IonicContact OD1-CZ 3.54Å; D332-R346 IonicContact OD1-NH1 2.77Å; D332-R346 IonicContact OD1-NH2 3.17Å; D332-R346 PolarHBondContact OD1-NH2 3.3Å; D332-R346 IonicContact OD2-CZ 3.73Å; D332-R346 IonicContact OD2-NH1 2.84Å; D332-R346 PolarHBondContact OD2-NH1 2.91Å; D332-R346 IonicContact OD2-NH2 2.94Å; D332-R346 PolarHBondContact OD2-NH2 2.76Å; D332-R346 VanDerWaalsContact OD2-NH2 3.14Å; P344-R346 HydrophobicContact CG-CG 4.37Å; P344-R346 PolarHBondContact O-N 2.92Å; R346-H348 PolarHBondContact O-N 3.29Å
347K97.4Very high95.5Very high63 Ų6359.3 Ų59.327%0.27431%0.307SS..  trans-65.8121-174.2-65.3173.9178-172.10111.2V34 D345 F351 V352 E355V34-K347 HydrophobicContact CG2-CB 4.46Å; V34-K347 HydrophobicContact CG2-CG 3.86Å; D345-K347 VanDerWaalsContact OD1-CB 3.32Å; D345-K347 WeakPolarHBondContact OD1-CB 3.41Å; D345-K347 WeakPolarHBondContact OD1-CG 3.47Å; D345-K347 PolarHBondContact OD1-N 3.12Å; K347-F351 HydrophobicContact CB-CD1 4.09Å; K347-F351 HydrophobicContact CD-CD1 3.97Å; K347-F351 HydrophobicContact CD-CE1 4.11Å; K347-F351 HydrophobicContact CG-CD1 3.61Å; K347-F351 HydrophobicContact CG-CE1 3.92Å; K347-F351 HydrophobicContact CG-CG 4.43Å; K347-V352 HydrophobicContact CB-CG2 3.65Å; K347-E355 IonicContact NZ-OE1 3.29Å; K347-E355 PolarHBondContact NZ-OE1 3.06Å; K347-E355 IonicContact NZ-OE2 3.13Å; K347-E355 PolarHBondContact NZ-OE2 2.84Å
348H97.3Very high95.5Very high1 Ų152.8 Ų52.81%0.00528%0.281CS..  trans-81165.4171.862.777.5000111V34 Q35 G299 E322 S324 R346 L350 F351 V352V34-H348 WeakPolarHBondContact CG1-CD2 3.48Å; Q35-H348 PolarHBondContact O-NE2 3.08Å; Q35-H348 VanDerWaalsContact O-NE2 3.17Å; G299-H348 PolarHBondContact O-CE1 3.06Å; G299-H348 VanDerWaalsContact O-CE1 3.24Å; G299-H348 PolarHBondContact O-NE2 3.28Å; E322-H348 PolarHBondContact O-ND1 2.75Å; S324-H348 VanDerWaalsContact O-CB 3.27Å; S324-H348 WeakPolarHBondContact O-CB 3.45Å; R346-H348 PolarHBondContact O-N 3.29Å; H348-L350 VanDerWaalsContact C-N 3.35Å; H348-L350 PolarHBondContact ND1-N 3.37Å; H348-L350 PolarHBondContact O-N 3.18Å; H348-F351 PolarHBondContact CE1-N 3.07Å; H348-F351 PolarHBondContact ND1-N 3.3Å; H348-F351 VanDerWaalsContact ND1-N 3.19Å; H348-F351 WeakPolarHBondContact O-CB 3.38Å; H348-F351 PolarHBondContact O-N 3.1Å; H348-V352 PolarHBondContact O-N 3.45Å; H348-V352 VanDerWaalsContact O-N 3.16Å
349P96.9Very high95.5Very high74 Ų7450.7 Ų50.748%0.48127%0.272SS..Hα-helixtrans-53.7-43-173.3-30.236.7000115.2E322E322-P349 WeakPolarHBondContact O-CD 3.45Å
350L97.6Very high95.5Very high0 Ų050 Ų500%027%0.271CS..Hα-helixtrans-64.2-44.5176.6175.562.7000112.1T300 E322 T323 H348 V352 K353 H354 V408 E411 L412 Y415T300-L350 HydrophobicContact CG2-CD1 4.34Å; T300-L350 HydrophobicContact CG2-CD2 3.78Å; T300-L350 HydrophobicContact CG2-CG 3.61Å; E322-L350 WeakPolarHBondContact O-CB 3.06Å; E322-L350 PolarHBondContact O-N 3.14Å; E322-L350 VanDerWaalsContact O-N 3.11Å; T323-L350 HydrophobicContact CG2-CB 4.41Å; T323-L350 HydrophobicContact CG2-CD2 3.8Å; H348-L350 VanDerWaalsContact C-N 3.35Å; H348-L350 PolarHBondContact ND1-N 3.37Å; H348-L350 PolarHBondContact O-N 3.18Å; L350-V352 PolarHBondContact O-N 3.01Å; L350-K353 PolarHBondContact O-N 3.27Å; L350-H354 WeakPolarHBondContact O-CB 3.2Å; L350-H354 PolarHBondContact O-N 3.5Å; L350-V408 HydrophobicContact CB-CG1 4.2Å; L350-V408 HydrophobicContact CD1-CG1 4.17Å; L350-V408 HydrophobicContact CD2-CG1 4.05Å; L350-V408 HydrophobicContact CD2-CG2 4.32Å; L350-V408 HydrophobicContact CG-CG1 4.35Å; L350-E411 HydrophobicContact CD1-CG 4.36Å; L350-L412 HydrophobicContact CD1-CD2 3.87Å; L350-L412 HydrophobicContact CD1-CG 4.26Å; L350-Y415 HydrophobicContact CD1-CE2 4Å
351F97.1Very high95.4Very high10 Ų1050.6 Ų50.64%0.04427%0.274CS..Hα-helixtrans-59-45.8-179.3-167.6-77.3000111.8V34 P301 K347 H348 K353 H354 E355V34-F351 HydrophobicContact CB-CD2 4.36Å; V34-F351 HydrophobicContact CB-CE2 4.4Å; V34-F351 HydrophobicContact CG1-CB 4.5Å; V34-F351 HydrophobicContact CG1-CD2 3.91Å; V34-F351 HydrophobicContact CG1-CE2 4.41Å; V34-F351 HydrophobicContact CG1-CG 4.28Å; V34-F351 HydrophobicContact CG2-CD1 4.34Å; V34-F351 HydrophobicContact CG2-CD2 4.11Å; V34-F351 HydrophobicContact CG2-CE1 4.28Å; V34-F351 HydrophobicContact CG2-CE2 4.02Å; V34-F351 HydrophobicContact CG2-CG 4.26Å; V34-F351 HydrophobicContact CG2-CZ 4.11Å; P301-F351 HydrophobicContact CG-CD2 4.41Å; P301-F351 HydrophobicContact CG-CE2 3.57Å; P301-F351 HydrophobicContact CG-CZ 4.07Å; K347-F351 HydrophobicContact CB-CD1 4.09Å; K347-F351 HydrophobicContact CD-CD1 3.97Å; K347-F351 HydrophobicContact CD-CE1 4.11Å; K347-F351 HydrophobicContact CG-CD1 3.61Å; K347-F351 HydrophobicContact CG-CE1 3.92Å; K347-F351 HydrophobicContact CG-CG 4.43Å; H348-F351 PolarHBondContact CE1-N 3.07Å; H348-F351 PolarHBondContact ND1-N 3.3Å; H348-F351 VanDerWaalsContact ND1-N 3.19Å; H348-F351 WeakPolarHBondContact O-CB 3.38Å; H348-F351 PolarHBondContact O-N 3.1Å; F351-K353 PolarHBondContact O-N 3.46Å; F351-H354 PolarHBondContact O-N 3.24Å; F351-H354 VanDerWaalsContact O-N 3.17Å; F351-E355 PolarHBondContact O-N 3.04Å
352V96.4Very high95.2Very high64 Ų6451.3 Ų51.339%0.38828%0.278SS..Hα-helixtrans-56.8-40.2179.7174.80000111.5K347 H348 L350K347-V352 HydrophobicContact CB-CG2 3.65Å; H348-V352 PolarHBondContact O-N 3.45Å; H348-V352 VanDerWaalsContact O-N 3.16Å; L350-V352 PolarHBondContact O-N 3.01Å
353K96.5Very high95.2Very high117 Ų11751.9 Ų51.951%0.50928%0.282SS..Hα-helixtrans-76.4-40.3178.5-62.4-62-171.9179.80111.7L350 F351 E355 V356 I357 L412 Y415L350-K353 PolarHBondContact O-N 3.27Å; F351-K353 PolarHBondContact O-N 3.46Å; K353-E355 VanDerWaalsContact C-N 3.34Å; K353-E355 PolarHBondContact O-N 2.86Å; K353-V356 PolarHBondContact O-N 2.82Å; K353-I357 WeakPolarHBondContact O-CG1 3.05Å; K353-I357 PolarHBondContact O-N 2.78Å; K353-I357 VanDerWaalsContact O-N 3.13Å; K353-L412 HydrophobicContact CB-CD2 3.76Å; K353-L412 HydrophobicContact CG-CD2 3.77Å; K353-Y415 HydrophobicContact CB-CD2 3.79Å; K353-Y415 HydrophobicContact CB-CE2 4.22Å
354H96.2Very high95.2Very high6 Ų654.1 Ų54.13%0.02829%0.289CS..Hα-helixtrans-59.5-43.3177.8-177.386.6000112.2T300 P301 R305 S306 L350 F351 V356 I357 A358 Y415T300-H354 HydrophobicContact CG2-CB 3.58Å; P301-H354 PolarHBondContact O-NE2 2.88Å; P301-H354 VanDerWaalsContact O-NE2 3.12Å; R305-H354 PolarHBondContact O-CE1 3.37Å; S306-H354 PolarHBondContact OG-CE1 2.65Å; S306-H354 VanDerWaalsContact OG-CE1 3.22Å; L350-H354 WeakPolarHBondContact O-CB 3.2Å; L350-H354 PolarHBondContact O-N 3.5Å; F351-H354 PolarHBondContact O-N 3.24Å; F351-H354 VanDerWaalsContact O-N 3.17Å; H354-V356 VanDerWaalsContact C-N 3.3Å; H354-V356 PolarHBondContact O-N 3.42Å; H354-I357 CarbonylContact O-C 3.52Å; H354-I357 PolarHBondContact O-N 3.33Å; H354-A358 WeakPolarHBondContact O-CB 3.33Å; H354-A358 PolarHBondContact O-N 3.42Å; H354-Y415 HydrophobicContact CB-CE2 4.22Å; H354-Y415 PolarHBondContact ND1-OH 3.49Å
355E95Very high94.9Very high91 Ų9160.4 Ų60.443%0.42531%0.312SS..Hα-helixtrans-57.3-42.4178.6-174179.1-132.800112.1K347 F351 K353 A359K347-E355 IonicContact NZ-OE1 3.29Å; K347-E355 PolarHBondContact NZ-OE1 3.06Å; K347-E355 IonicContact NZ-OE2 3.13Å; K347-E355 PolarHBondContact NZ-OE2 2.84Å; F351-E355 PolarHBondContact O-N 3.04Å; K353-E355 VanDerWaalsContact C-N 3.34Å; K353-E355 PolarHBondContact O-N 2.86Å; E355-A359 PolarHBondContact O-N 3.18Å
356V95.1Very high94.8Very high84 Ų8463.1 Ų63.151%0.50932%0.322SS..Hα-helixtrans-65.2-41.2175.8177.90000111.2K353 H354 A359 I360K353-V356 PolarHBondContact O-N 2.82Å; H354-V356 VanDerWaalsContact C-N 3.3Å; H354-V356 PolarHBondContact O-N 3.42Å; V356-A359 PolarHBondContact O-N 3.25Å; V356-I360 HydrophobicContact CG1-CD1 4.12Å; V356-I360 WeakPolarHBondContact O-CG1 3.35Å; V356-I360 PolarHBondContact O-N 3.09Å; V356-I360 VanDerWaalsContact O-N 3.11Å
357I95.1Very high94.5Very high7 Ų767.3 Ų67.34%0.03634%0.338CS..Hα-helixtrans-70.5-40.5-178.9-67.3-68.6000111.6K353 H354 A359 I360 I361 I371 Y415K353-I357 WeakPolarHBondContact O-CG1 3.05Å; K353-I357 PolarHBondContact O-N 2.78Å; K353-I357 VanDerWaalsContact O-N 3.13Å; H354-I357 CarbonylContact O-C 3.52Å; H354-I357 PolarHBondContact O-N 3.33Å; I357-A359 VanDerWaalsContact C-N 3.3Å; I357-A359 PolarHBondContact O-N 3Å; I357-I360 HydrophobicContact CD1-CD1 4.31Å; I357-I360 WeakPolarHBondContact O-CB 3.38Å; I357-I360 PolarHBondContact O-N 3.12Å; I357-I360 VanDerWaalsContact O-N 3.09Å; I357-I361 HydrophobicContact CG2-CD1 3.87Å; I357-I361 HydrophobicContact CG2-CG1 4.33Å; I357-I361 WeakPolarHBondContact O-CG1 3.39Å; I357-I361 PolarHBondContact O-N 3.48Å; I357-I371 HydrophobicContact CG2-CG2 3.79Å; I357-Y415 HydrophobicContact CB-CD1 4.26Å; I357-Y415 HydrophobicContact CB-CE1 4.33Å; I357-Y415 HydrophobicContact CB-CG 4.48Å; I357-Y415 HydrophobicContact CD1-CD1 4.19Å; I357-Y415 HydrophobicContact CD1-CG 4.08Å; I357-Y415 HydrophobicContact CG1-CD1 3.72Å; I357-Y415 HydrophobicContact CG1-CD2 3.94Å; I357-Y415 HydrophobicContact CG1-CE1 4.24Å; I357-Y415 HydrophobicContact CG1-CE2 4.4Å; I357-Y415 HydrophobicContact CG1-CG 3.55Å; I357-Y415 HydrophobicContact CG2-CD1 3.96Å; I357-Y415 HydrophobicContact CG2-CE1 3.91Å
358A93.1Very high94.3Very high15 Ų1564.4 Ų64.412%0.12433%0.326CS..Hα-helixtrans-57-45.6173.900000111H354 I360 I361 E362H354-A358 WeakPolarHBondContact O-CB 3.33Å; H354-A358 PolarHBondContact O-N 3.42Å; A358-I360 VanDerWaalsContact C-N 3.32Å; A358-I360 PolarHBondContact O-N 2.94Å; A358-I361 PolarHBondContact O-N 2.91Å; A358-E362 PolarHBondContact O-N 3.03Å; A358-E362 VanDerWaalsContact O-N 3.11Å
359A93.4Very high94.2Very high48 Ų4869.3 Ų69.340%0.39735%0.348SS..Hα-helixtrans-62.3-37.1175.200000112.8E355 V356 I357 S363E355-A359 PolarHBondContact O-N 3.18Å; V356-A359 PolarHBondContact O-N 3.25Å; I357-A359 VanDerWaalsContact C-N 3.3Å; I357-A359 PolarHBondContact O-N 3Å; A359-S363 VanDerWaalsContact O-CB 3.22Å; A359-S363 WeakPolarHBondContact O-CB 3.42Å; A359-S363 PolarHBondContact O-N 3.12Å; A359-S363 PolarHBondContact O-OG 3.38Å
360I93.8Very high94Very high23 Ų2372 Ų7212%0.11835%0.352CS..Hα-helixtrans-67.2-42.9175.3-70.7166.1000111.2V356 I357 A358 E362 S363 Y364 R367 I371V356-I360 HydrophobicContact CG1-CD1 4.12Å; V356-I360 WeakPolarHBondContact O-CG1 3.35Å; V356-I360 PolarHBondContact O-N 3.09Å; V356-I360 VanDerWaalsContact O-N 3.11Å; I357-I360 HydrophobicContact CD1-CD1 4.31Å; I357-I360 WeakPolarHBondContact O-CB 3.38Å; I357-I360 PolarHBondContact O-N 3.12Å; I357-I360 VanDerWaalsContact O-N 3.09Å; A358-I360 VanDerWaalsContact C-N 3.32Å; A358-I360 PolarHBondContact O-N 2.94Å; I360-E362 VanDerWaalsContact C-N 3.29Å; I360-E362 PolarHBondContact O-N 3.02Å; I360-S363 PolarHBondContact O-N 2.87Å; I360-Y364 HydrophobicContact CB-CD2 4.46Å; I360-Y364 HydrophobicContact CG2-CD2 4.08Å; I360-Y364 PolarHBondContact O-N 2.98Å; I360-R367 HydrophobicContact CG2-CG 4.12Å; I360-I371 HydrophobicContact CG2-CD1 3.71Å
361I93Very high93.9Very high28 Ų2872 Ų7214%0.14435%0.352CS..Hα-helixtrans-58.6-44.2178.9-71.4167.3000110.4R305 I357 A358 I371R305-I361 HydrophobicContact CB-CD1 4.35Å; R305-I361 HydrophobicContact CG-CD1 4.46Å; I357-I361 HydrophobicContact CG2-CD1 3.87Å; I357-I361 HydrophobicContact CG2-CG1 4.33Å; I357-I361 WeakPolarHBondContact O-CG1 3.39Å; I357-I361 PolarHBondContact O-N 3.48Å; A358-I361 PolarHBondContact O-N 2.91Å; I361-I371 HydrophobicContact CD1-CG2 3.96Å; I361-I371 HydrophobicContact CG1-CB 4.31Å; I361-I371 HydrophobicContact CG1-CD1 4.38Å; I361-I371 HydrophobicContact CG1-CG2 4.17Å
362E89.4Confident93.8Very high128 Ų12873.2 Ų73.260%0.59836%0.361SS*.Hα-helixtrans-69.1-41177.6-70.3179.8166.500112.9R305 A358 I360R305-E362 IonicContact CZ-OE1 2.87Å; R305-E362 IonicContact NH1-OE1 3.17Å; R305-E362 PolarHBondContact NH1-OE1 2.99Å; R305-E362 IonicContact NH2-OE1 3.58Å; R305-E362 PolarHBondContact NH2-OE1 3.05Å; A358-E362 PolarHBondContact O-N 3.03Å; A358-E362 VanDerWaalsContact O-N 3.11Å; I360-E362 VanDerWaalsContact C-N 3.29Å; I360-E362 PolarHBondContact O-N 3.02Å
363S94Very high93.8Very high85 Ų8576.4 Ų76.459%0.59437%0.372SS*.Hα-helixtrans-82.5-27.7-170.9-59.90000113.7A359 I360A359-S363 VanDerWaalsContact O-CB 3.22Å; A359-S363 WeakPolarHBondContact O-CB 3.42Å; A359-S363 PolarHBondContact O-N 3.12Å; A359-S363 PolarHBondContact O-OG 3.38Å; I360-S363 PolarHBondContact O-N 2.87Å
364Y93.5Very high93.8Very high138 Ų13873.9 Ų73.954%0.54136%0.363SS..  trans-129.985.3-170-59.7-82000111.9I360 E366 R367 G368I360-Y364 HydrophobicContact CB-CD2 4.46Å; I360-Y364 HydrophobicContact CG2-CD2 4.08Å; I360-Y364 PolarHBondContact O-N 2.98Å; Y364-E366 PolarHBondContact O-N 2.73Å; Y364-R367 PolarHBondContact O-N 3.48Å; Y364-R367 VanDerWaalsContact O-N 3.11Å; Y364-G368 PolarHBondContact O-N 2.99Å
365K90.1Very high93.8Very high165 Ų16573.6 Ų73.672%0.71736%0.362SS*.Hα-helixtrans-44.9-54.6-171.6-167177.7-177.7178.70115.4G368 Q369K365-G368 PolarHBondContact O-N 3.4Å; K365-Q369 WeakPolarHBondContact O-CB 3.33Å; K365-Q369 VanDerWaalsContact O-CG 3.27Å; K365-Q369 WeakPolarHBondContact O-CG 3.38Å; K365-Q369 PolarHBondContact O-N 3.4Å
366E92.4Very high93.9Very high168 Ų16871.3 Ų71.379%0.78535%0.35SS*.Hα-helixtrans-67.2-43.1-177.7-67.8-178.7-179.600112.6Y364 K370Y364-E366 PolarHBondContact O-N 2.73Å; E366-K370 PolarHBondContact O-N 3.05Å; E366-K370 VanDerWaalsContact O-N 3.13Å
367R91.9Very high94Very high99 Ų9971.9 Ų71.937%0.37435%0.347SS..Hα-helixtrans-66.6-42177.9-173.8178.5-179.9-161.5-0.8110.7I360 Y364 K370 I371 T418I360-R367 HydrophobicContact CG2-CG 4.12Å; Y364-R367 PolarHBondContact O-N 3.48Å; Y364-R367 VanDerWaalsContact O-N 3.11Å; R367-K370 PolarHBondContact O-N 3.37Å; R367-I371 HydrophobicContact CG-CD1 4.1Å; R367-I371 VanDerWaalsContact O-CG1 3.31Å; R367-I371 WeakPolarHBondContact O-CG1 3.22Å; R367-I371 PolarHBondContact O-N 3.1Å; R367-T418 PolarHBondContact NE-O 3.42Å; R367-T418 PolarHBondContact NH2-O 2.65Å; R367-T418 PolarHBondContact NH2-OXT 3.42Å
368G93.5Very high94.1Very high2 Ų272.1 Ų72.12%0.02135%0.348CS..Hα-helixtrans-59.4-48.7175.400000112.1Y364 K365 K370 I371 T372Y364-G368 PolarHBondContact O-N 2.99Å; K365-G368 PolarHBondContact O-N 3.4Å; G368-K370 VanDerWaalsContact C-N 3.33Å; G368-K370 PolarHBondContact O-N 2.85Å; G368-I371 WeakPolarHBondContact O-CB 3.48Å; G368-I371 PolarHBondContact O-N 2.89Å; G368-T372 PolarHBondContact O-N 3.01Å; G368-T372 PolarHBondContact O-OG1 3.09Å; G368-T372 VanDerWaalsContact O-OG1 3.12Å
369Q93.4Very high94.4Very high104 Ų10471.9 Ų71.949%0.48635%0.345SS..Hα-helixtrans-55.7-47.7174.7-77.3175-18.200111.8K365 I371 T372 E373K365-Q369 WeakPolarHBondContact O-CB 3.33Å; K365-Q369 VanDerWaalsContact O-CG 3.27Å; K365-Q369 WeakPolarHBondContact O-CG 3.38Å; K365-Q369 PolarHBondContact O-N 3.4Å; Q369-I371 PolarHBondContact O-N 2.78Å; Q369-T372 PolarHBondContact O-N 3.34Å; Q369-E373 WeakPolarHBondContact O-CB 3.11Å; Q369-E373 VanDerWaalsContact O-CG 3.31Å; Q369-E373 WeakPolarHBondContact O-CG 3.12Å; Q369-E373 PolarHBondContact O-N 3.04Å
370K94.6Very high94.5Very high130 Ų13076 Ų7657%0.56535%0.353SS*.Hα-helixtrans-62.7-39.4177.9-171.8179.1-178-177.40112.9E366 R367 G368 N374E366-K370 PolarHBondContact O-N 3.05Å; E366-K370 VanDerWaalsContact O-N 3.13Å; R367-K370 PolarHBondContact O-N 3.37Å; G368-K370 VanDerWaalsContact C-N 3.33Å; G368-K370 PolarHBondContact O-N 2.85Å; K370-N374 PolarHBondContact O-N 3.12Å; K370-N374 VanDerWaalsContact O-N 3.11Å; K370-N374 PolarHBondContact O-ND2 2.64Å; K370-N374 VanDerWaalsContact O-ND2 3.08Å
371I94.9Very high94.7Very high0 Ų079.2 Ų79.20%037%0.368CS..Hα-helixtrans-60.7-54174.2-70.1159.9000109.3I357 I360 I361 R367 G368 Q369 E373 N374 L375 T418I357-I371 HydrophobicContact CG2-CG2 3.79Å; I360-I371 HydrophobicContact CG2-CD1 3.71Å; I361-I371 HydrophobicContact CD1-CG2 3.96Å; I361-I371 HydrophobicContact CG1-CB 4.31Å; I361-I371 HydrophobicContact CG1-CD1 4.38Å; I361-I371 HydrophobicContact CG1-CG2 4.17Å; R367-I371 HydrophobicContact CG-CD1 4.1Å; R367-I371 VanDerWaalsContact O-CG1 3.31Å; R367-I371 WeakPolarHBondContact O-CG1 3.22Å; R367-I371 PolarHBondContact O-N 3.1Å; G368-I371 WeakPolarHBondContact O-CB 3.48Å; G368-I371 PolarHBondContact O-N 2.89Å; Q369-I371 PolarHBondContact O-N 2.78Å; I371-E373 VanDerWaalsContact C-N 3.31Å; I371-E373 PolarHBondContact O-N 3.37Å; I371-N374 WeakPolarHBondContact O-CB 2.88Å; I371-N374 PolarHBondContact O-N 3.34Å; I371-N374 VanDerWaalsContact O-N 3.09Å; I371-L375 HydrophobicContact CG2-CD1 3.85Å; I371-L375 HydrophobicContact CG2-CG 4.22Å; I371-L375 WeakPolarHBondContact O-CG 3.04Å; I371-L375 PolarHBondContact O-N 3.45Å; I371-T418 HydrophobicContact CB-CG2 4.48Å; I371-T418 HydrophobicContact CD1-CG2 4.44Å; I371-T418 VanDerWaalsContact CG1-CB 3.45Å; I371-T418 HydrophobicContact CG1-CG2 3.44Å; I371-T418 VanDerWaalsContact CG1-CG2 3.44Å
372T94.9Very high94.8Very high36 Ų3678.2 Ų78.222%0.22136%0.364CS..Hα-helixtrans-57.9-42.9-178.9-58.20000111.7G368 Q369 N374 L375 R376G368-T372 PolarHBondContact O-N 3.01Å; G368-T372 PolarHBondContact O-OG1 3.09Å; G368-T372 VanDerWaalsContact O-OG1 3.12Å; Q369-T372 PolarHBondContact O-N 3.34Å; T372-N374 PolarHBondContact O-N 2.77Å; T372-L375 PolarHBondContact O-N 2.83Å; T372-R376 HydrophobicContact CG2-CG 4.4Å; T372-R376 VanDerWaalsContact O-CG 3.26Å; T372-R376 WeakPolarHBondContact O-CG 3.3Å; T372-R376 PolarHBondContact O-N 2.97Å
373E95.8Very high95.2Very high131 Ų13172.3 Ų72.361%0.61234%0.336SS*.Hα-helixtrans-58.9-45.1175.1-75.3171.5-178.200112.4Q369 I371 R376 Q377Q369-E373 WeakPolarHBondContact O-CB 3.11Å; Q369-E373 VanDerWaalsContact O-CG 3.31Å; Q369-E373 WeakPolarHBondContact O-CG 3.12Å; Q369-E373 PolarHBondContact O-N 3.04Å; I371-E373 VanDerWaalsContact C-N 3.31Å; I371-E373 PolarHBondContact O-N 3.37Å; E373-R376 PolarHBondContact O-N 3.46Å; E373-Q377 WeakPolarHBondContact O-CB 3.17Å; E373-Q377 PolarHBondContact O-N 3.43Å
374N96.6Very high95.3Very high63 Ų6376.3 Ų76.334%0.33734%0.343SS..Hα-helixtrans-64.9-39.6177.3-68.7-31.7000112.1K370 I371 T372 Q377 L378 V414K370-N374 PolarHBondContact O-N 3.12Å; K370-N374 VanDerWaalsContact O-N 3.11Å; K370-N374 PolarHBondContact O-ND2 2.64Å; K370-N374 VanDerWaalsContact O-ND2 3.08Å; I371-N374 WeakPolarHBondContact O-CB 2.88Å; I371-N374 PolarHBondContact O-N 3.34Å; I371-N374 VanDerWaalsContact O-N 3.09Å; T372-N374 PolarHBondContact O-N 2.77Å; N374-Q377 PolarHBondContact O-N 2.85Å; N374-L378 PolarHBondContact O-N 3.48Å; N374-V414 HydrophobicContact CB-CG1 3.66Å; N374-V414 HydrophobicContact CB-CG2 4.47Å
375L96.8Very high95.3Very high0 Ų075.1 Ų75.10%034%0.341CS..Hα-helixtrans-65-40.7176-65.5177.3000111.5R305 V307 I371 T372 Q377 L378 E379 E411 V414 Y415R305-L375 WeakPolarHBondContact O-CD1 3.38Å; V307-L375 HydrophobicContact CG2-CB 3.69Å; V307-L375 HydrophobicContact CG2-CD2 3.68Å; V307-L375 HydrophobicContact CG2-CG 4.15Å; I371-L375 HydrophobicContact CG2-CD1 3.85Å; I371-L375 HydrophobicContact CG2-CG 4.22Å; I371-L375 WeakPolarHBondContact O-CG 3.04Å; I371-L375 PolarHBondContact O-N 3.45Å; T372-L375 PolarHBondContact O-N 2.83Å; L375-Q377 VanDerWaalsContact C-N 3.34Å; L375-L378 PolarHBondContact O-N 3.36Å; L375-E379 PolarHBondContact O-N 2.79Å; L375-E411 HydrophobicContact CD2-CG 4.08Å; L375-V414 HydrophobicContact CD2-CB 4.1Å; L375-V414 HydrophobicContact CD2-CG1 3.79Å; L375-V414 HydrophobicContact CG-CG1 4.27Å; L375-Y415 HydrophobicContact CD1-CE1 4.07Å; L375-Y415 HydrophobicContact CD2-CD1 4.22Å; L375-Y415 HydrophobicContact CD2-CE1 3.7Å; L375-Y415 HydrophobicContact CG-CE1 4.49Å
376R97.3Very high95.6Very high43 Ų4367.3 Ų67.316%0.16231%0.307CS..Hα-helixtrans-67.6-34.6174.8-65.6-68.6147.2-101.5-10.5112.2P303 E304 S306 T372 E373 E379 K380P303-R376 PolarHBondContact O-NH2 3.2Å; P303-R376 VanDerWaalsContact O-NH2 3.1Å; E304-R376 VanDerWaalsContact C-NH2 3.28Å; E304-R376 PolarHBondContact O-NH2 2.6Å; S306-R376 VanDerWaalsContact O-CZ 3.3Å; S306-R376 PolarHBondContact O-NH1 3.47Å; S306-R376 PolarHBondContact O-NH2 2.79Å; T372-R376 HydrophobicContact CG2-CG 4.4Å; T372-R376 VanDerWaalsContact O-CG 3.26Å; T372-R376 WeakPolarHBondContact O-CG 3.3Å; T372-R376 PolarHBondContact O-N 2.97Å; E373-R376 PolarHBondContact O-N 3.46Å; R376-E379 IonicContact NH1-OE1 3.83Å; R376-E379 PolarHBondContact NH1-OE1 3.1Å; R376-E379 IonicContact NH1-OE2 2.75Å; R376-E379 PolarHBondContact NH1-OE2 3.26Å; R376-E379 VanDerWaalsContact NH1-OE2 3.13Å; R376-K380 VanDerWaalsContact O-CG 3.32Å; R376-K380 WeakPolarHBondContact O-CG 3.44Å; R376-K380 PolarHBondContact O-N 2.92Å
377Q97.2Very high95.8Very high96 Ų9662.1 Ų62.145%0.44928%0.282SS..Hα-helixtrans-66.4-45.5174.8-176.657.635.700111.3E373 N374 L375 E379 K380 E381E373-Q377 WeakPolarHBondContact O-CB 3.17Å; E373-Q377 PolarHBondContact O-N 3.43Å; N374-Q377 PolarHBondContact O-N 2.85Å; L375-Q377 VanDerWaalsContact C-N 3.34Å; Q377-E379 VanDerWaalsContact C-N 3.34Å; Q377-E379 PolarHBondContact O-N 3.37Å; Q377-K380 PolarHBondContact O-N 3.43Å; Q377-E381 PolarHBondContact NE2-OE1 3.5Å; Q377-E381 WeakPolarHBondContact O-CG 3.47Å; Q377-E381 PolarHBondContact O-N 2.94Å
378L97.3Very high95.8Very high13 Ų1361.7 Ų61.77%0.06829%0.287CS..Hα-helixtrans-56-48.1173.7172.260.5000111.6V307 N374 L375 K380 E381 A382 E410 E411V307-L378 HydrophobicContact CG1-CD2 4.3Å; V307-L378 HydrophobicContact CG1-CG 4.33Å; V307-L378 HydrophobicContact CG2-CD2 4.38Å; N374-L378 PolarHBondContact O-N 3.48Å; L375-L378 PolarHBondContact O-N 3.36Å; L378-K380 PolarHBondContact O-N 3.39Å; L378-E381 PolarHBondContact O-N 3.08Å; L378-A382 PolarHBondContact O-N 3.5Å; L378-E410 HydrophobicContact CD1-CB 3.7Å; L378-E410 HydrophobicContact CD1-CG 4.45Å; L378-E410 WeakPolarHBondContact CD1-OE2 3.48Å; L378-E410 HydrophobicContact CD2-CB 4.1Å; L378-E411 HydrophobicContact CD2-CB 3.94Å
379E97.9Very high95.8Very high10 Ų1061.6 Ų61.65%0.04729%0.286CS..Hα-helixtrans-57.5-48.9177-176.416989.200112.2R263 V307 F308 L375 R376 Q377 E381 A382 M383R263-E379 IonicContact CZ-OE1 2.68Å; R263-E379 VanDerWaalsContact CZ-OE1 3.29Å; R263-E379 IonicContact CZ-OE2 2.65Å; R263-E379 IonicContact NH1-OE1 3.55Å; R263-E379 PolarHBondContact NH1-OE1 3.14Å; R263-E379 IonicContact NH1-OE2 2.83Å; R263-E379 IonicContact NH2-OE1 2.86Å; R263-E379 PolarHBondContact NH2-OE1 2.99Å; R263-E379 IonicContact NH2-OE2 3.65Å; R263-E379 PolarHBondContact NH2-OE2 2.71Å; V307-E379 HydrophobicContact CG1-CB 4.15Å; F308-E379 HydrophobicContact CB-CG 4.43Å; F308-E379 WeakPolarHBondContact CB-OE2 3.35Å; F308-E379 WeakPolarHBondContact CD2-OE2 3.4Å; F308-E379 PolarHBondContact N-OE2 2.9Å; L375-E379 PolarHBondContact O-N 2.79Å; R376-E379 IonicContact NH1-OE1 3.83Å; R376-E379 PolarHBondContact NH1-OE1 3.1Å; R376-E379 IonicContact NH1-OE2 2.75Å; R376-E379 PolarHBondContact NH1-OE2 3.26Å; R376-E379 VanDerWaalsContact NH1-OE2 3.13Å; Q377-E379 VanDerWaalsContact C-N 3.34Å; Q377-E379 PolarHBondContact O-N 3.37Å; E379-E381 VanDerWaalsContact C-N 3.31Å; E379-E381 PolarHBondContact O-N 3.19Å; E379-A382 WeakPolarHBondContact O-CB 3.38Å; E379-A382 PolarHBondContact O-N 3.03Å; E379-M383 HydrophobicContact CG-CG 4.5Å; E379-M383 HydrophobicContact CG-SD 4.12Å; E379-M383 VanDerWaalsContact O-CG 3.31Å; E379-M383 WeakPolarHBondContact O-CG 3.22Å; E379-M383 PolarHBondContact O-N 2.81Å
380K97.3Very high95.9Very high133 Ų13356.8 Ų56.858%0.57826%0.264SS*.Hα-helixtrans-60.3-40178.2-75.2174.8-178.9178.90112.5R376 Q377 L378 K384R376-K380 VanDerWaalsContact O-CG 3.32Å; R376-K380 WeakPolarHBondContact O-CG 3.44Å; R376-K380 PolarHBondContact O-N 2.92Å; Q377-K380 PolarHBondContact O-N 3.43Å; L378-K380 PolarHBondContact O-N 3.39Å; K380-K384 WeakPolarHBondContact O-CB 3.43Å; K380-K384 PolarHBondContact O-N 3Å
381E96.6Very high95.8Very high92 Ų9253.5 Ų53.543%0.4326%0.261SS..Hα-helixtrans-66.4-42.1177.1-73.8175-16600111.8Q377 L378 E379 K384 K385Q377-E381 PolarHBondContact NE2-OE1 3.5Å; Q377-E381 WeakPolarHBondContact O-CG 3.47Å; Q377-E381 PolarHBondContact O-N 2.94Å; L378-E381 PolarHBondContact O-N 3.08Å; E379-E381 VanDerWaalsContact C-N 3.31Å; E379-E381 PolarHBondContact O-N 3.19Å; E381-K384 PolarHBondContact O-N 3.29Å; E381-K385 WeakPolarHBondContact O-CG 3.48Å; E381-K385 PolarHBondContact O-N 2.97Å
382A96.3Very high95.8Very high6 Ų657.1 Ų57.15%0.0528%0.283CS..Hα-helixtrans-61.2-49.7174.300000111.1P310 L378 E379 K384 K385 M386P310-A382 HydrophobicContact CG-CB 4.18Å; L378-A382 PolarHBondContact O-N 3.5Å; E379-A382 WeakPolarHBondContact O-CB 3.38Å; E379-A382 PolarHBondContact O-N 3.03Å; A382-K384 VanDerWaalsContact C-N 3.35Å; A382-K384 PolarHBondContact O-N 2.96Å; A382-K385 WeakPolarHBondContact O-CB 3.33Å; A382-K385 PolarHBondContact O-N 3.2Å; A382-K385 VanDerWaalsContact O-N 3.15Å; A382-M386 WeakPolarHBondContact O-CG 3.49Å; A382-M386 PolarHBondContact O-N 2.9Å; A382-M386 VanDerWaalsContact O-N 3.11Å
383M96.8Very high95.7Very high4 Ų455.7 Ų55.72%0.0228%0.276CS..Hα-helixtrans-60-42.2178.3-69.4-177.771.200112.5A255 E256 M259 Y296 E379 K385 M386 E387A255-M383 HydrophobicContact CB-CE 3.62Å; E256-M383 HydrophobicContact CB-CE 4.35Å; E256-M383 VanDerWaalsContact CD-CE 3.48Å; E256-M383 HydrophobicContact CG-CE 3.49Å; E256-M383 VanDerWaalsContact CG-CE 3.49Å; E256-M383 HydrophobicContact CG-SD 4.06Å; M259-M383 HydrophobicContact CE-CE 3.99Å; M259-M383 HydrophobicContact CE-CG 4.44Å; M259-M383 HydrophobicContact CE-SD 3.88Å; M259-M383 HydrophobicContact SD-CE 4.11Å; M259-M383 HydrophobicContact SD-SD 3.65Å; M259-M383 VanDerWaalsContact SD-SD 3.65Å; Y296-M383 HydrophobicContact CE1-CG 3.88Å; E379-M383 HydrophobicContact CG-CG 4.5Å; E379-M383 HydrophobicContact CG-SD 4.12Å; E379-M383 VanDerWaalsContact O-CG 3.31Å; E379-M383 WeakPolarHBondContact O-CG 3.22Å; E379-M383 PolarHBondContact O-N 2.81Å; M383-K385 VanDerWaalsContact C-N 3.29Å; M383-K385 PolarHBondContact O-N 3.33Å; M383-M386 WeakPolarHBondContact O-CA 3.48Å; M383-M386 WeakPolarHBondContact O-CB 3.43Å; M383-M386 PolarHBondContact O-N 3.12Å; M383-E387 PolarHBondContact O-N 3.16Å
384K95.6Very high95.5Very high169 Ų16951.5 Ų51.574%0.73526%0.259SS*.Hα-helixtrans-59.8-39.1176.4-175.2179.4179.9-178.60112.4K380 E381 A382 M386K380-K384 WeakPolarHBondContact O-CB 3.43Å; K380-K384 PolarHBondContact O-N 3Å; E381-K384 PolarHBondContact O-N 3.29Å; A382-K384 VanDerWaalsContact C-N 3.35Å; A382-K384 PolarHBondContact O-N 2.96Å; K384-M386 VanDerWaalsContact C-N 3.3Å
385K94Very high95.1Very high114 Ų11455.5 Ų55.550%0.49628%0.276SS..Hα-helixtrans-64.2-38.4174.1-67.5169.8-176.1173.30110.8E381 A382 M383 N388E381-K385 WeakPolarHBondContact O-CG 3.48Å; E381-K385 PolarHBondContact O-N 2.97Å; A382-K385 WeakPolarHBondContact O-CB 3.33Å; A382-K385 PolarHBondContact O-N 3.2Å; A382-K385 VanDerWaalsContact O-N 3.15Å; M383-K385 VanDerWaalsContact C-N 3.29Å; M383-K385 PolarHBondContact O-N 3.33Å; K385-N388 WeakPolarHBondContact O-CB 3.48Å; K385-N388 PolarHBondContact O-N 3.37Å
386M96.7Very high94.9Very high1 Ų161.3 Ų61.31%0.00530%0.303CS..Hα-helixtrans-73-30.1-178.4-65.5-55.19800113.9V294 Y296 P310 V312 A382 M383 K384 N388 I389 L390 Y400 L403V294-M386 HydrophobicContact CG1-CB 3.98Å; V294-M386 HydrophobicContact CG1-CG 3.7Å; V294-M386 HydrophobicContact CG1-SD 3.81Å; V294-M386 HydrophobicContact CG2-CB 4.19Å; V294-M386 HydrophobicContact CG2-SD 4.27Å; Y296-M386 HydrophobicContact CE1-CG 4.09Å; Y296-M386 WeakPolarHBondContact OH-CB 3.1Å; P310-M386 HydrophobicContact CB-CG 3.63Å; P310-M386 HydrophobicContact CB-SD 3.68Å; P310-M386 HydrophobicContact CG-CG 4.03Å; P310-M386 HydrophobicContact CG-SD 4.11Å; V312-M386 HydrophobicContact CG2-SD 4.15Å; A382-M386 WeakPolarHBondContact O-CG 3.49Å; A382-M386 PolarHBondContact O-N 2.9Å; A382-M386 VanDerWaalsContact O-N 3.11Å; M383-M386 WeakPolarHBondContact O-CA 3.48Å; M383-M386 WeakPolarHBondContact O-CB 3.43Å; M383-M386 PolarHBondContact O-N 3.12Å; K384-M386 VanDerWaalsContact C-N 3.3Å; M386-N388 PolarHBondContact O-N 2.92Å; M386-I389 HydrophobicContact CE-CD1 3.47Å; M386-I389 VanDerWaalsContact CE-CD1 3.47Å; M386-I389 HydrophobicContact CE-CG1 4.45Å; M386-I389 WeakPolarHBondContact O-CA 2.97Å; M386-I389 WeakPolarHBondContact O-CB 3.3Å; M386-I389 PolarHBondContact O-N 3.32Å; M386-I389 HydrophobicContact SD-CD1 3.59Å; M386-I389 VanDerWaalsContact SD-CD1 3.59Å; M386-L390 WeakPolarHBondContact O-CG 3.3Å; M386-L390 PolarHBondContact O-N 2.84Å; M386-Y400 HydrophobicContact CE-CE1 4.25Å; M386-L403 HydrophobicContact CE-CD1 3.81Å; M386-L403 HydrophobicContact CE-CD2 3.78Å; M386-L403 HydrophobicContact CE-CG 4.45Å; M386-L403 HydrophobicContact SD-CD2 3.66Å
387E95.6Very high94.6Very high58 Ų5862 Ų6227%0.27131%0.313SS..Hα-helixtrans-59.1-32.6173.7-79.2-57138.600112.7R20 M383 L390 A391R20-E387 IonicContact CZ-OE2 3.31Å; R20-E387 VanDerWaalsContact CZ-OE2 3.26Å; R20-E387 VanDerWaalsContact NH1-CD 3.33Å; R20-E387 IonicContact NH1-OE1 2.78Å; R20-E387 PolarHBondContact NH1-OE1 2.87Å; R20-E387 IonicContact NH1-OE2 2.77Å; R20-E387 PolarHBondContact NH1-OE2 3.28Å; R20-E387 IonicContact NH2-OE2 2.93Å; R20-E387 PolarHBondContact NH2-OE2 3.1Å; M383-E387 PolarHBondContact O-N 3.16Å; E387-L390 PolarHBondContact O-N 3.09Å; E387-A391 VanDerWaalsContact O-CB 3.3Å; E387-A391 WeakPolarHBondContact O-CB 3.33Å; E387-A391 PolarHBondContact O-N 2.77Å
388N92.8Very high94.3Very high90 Ų9063 Ų6348%0.48132%0.321SS..Hα-helixtrans-63.3-45.6172.2-171.246.4000111.1K385 M386 L390 A391 V392K385-N388 WeakPolarHBondContact O-CB 3.48Å; K385-N388 PolarHBondContact O-N 3.37Å; M386-N388 PolarHBondContact O-N 2.92Å; N388-L390 VanDerWaalsContact C-N 3.33Å; N388-L390 PolarHBondContact O-N 3.29Å; N388-A391 PolarHBondContact O-N 2.58Å; N388-A391 VanDerWaalsContact O-N 3.1Å; N388-V392 VanDerWaalsContact O-CG2 3.31Å; N388-V392 WeakPolarHBondContact O-CG2 3.16Å; N388-V392 PolarHBondContact O-N 3.45Å; N388-V392 WeakPolarHBondContact OD1-CG2 3.49Å
389I93.4Very high94.1Very high0 Ų066.8 Ų66.80%034%0.342CS..Hα-helixtrans-61.7-43.2177.9-61.4178.1000111P292 V294 V312 M386 A391 G393 V394 Y400P292-I389 HydrophobicContact CB-CG2 4.47Å; P292-I389 HydrophobicContact CG-CG2 3.32Å; V294-I389 HydrophobicContact CG2-CG2 4.37Å; V312-I389 HydrophobicContact CG2-CD1 4.19Å; M386-I389 HydrophobicContact CE-CD1 3.47Å; M386-I389 VanDerWaalsContact CE-CD1 3.47Å; M386-I389 HydrophobicContact CE-CG1 4.45Å; M386-I389 WeakPolarHBondContact O-CA 2.97Å; M386-I389 WeakPolarHBondContact O-CB 3.3Å; M386-I389 PolarHBondContact O-N 3.32Å; M386-I389 HydrophobicContact SD-CD1 3.59Å; M386-I389 VanDerWaalsContact SD-CD1 3.59Å; I389-A391 PolarHBondContact O-N 3.42Å; I389-G393 WeakPolarHBondContact O-CA 3.44Å; I389-G393 PolarHBondContact O-N 3.41Å; I389-V394 HydrophobicContact CG2-CG2 4.06Å; I389-Y400 HydrophobicContact CD1-CD1 3.74Å; I389-Y400 HydrophobicContact CD1-CE1 3.23Å; I389-Y400 HydrophobicContact CD1-CE2 4.2Å; I389-Y400 HydrophobicContact CD1-CG 4.4Å; I389-Y400 VanDerWaalsContact CD1-CZ 3.46Å; I389-Y400 HydrophobicContact CG1-CE1 4.03Å
390L95.4Very high93.9Very high3 Ų368.3 Ų68.32%0.01635%0.347CS..Hα-helixtrans-67.9-16.7177.6-69.3167.8000113.4V284 P286 L291 V294 M386 E387 N388V284-L390 HydrophobicContact CB-CD1 4.03Å; V284-L390 HydrophobicContact CB-CD2 4.15Å; V284-L390 HydrophobicContact CG1-CD1 3.75Å; V284-L390 HydrophobicContact CG1-CD2 3.94Å; P286-L390 HydrophobicContact CG-CD2 3.75Å; L291-L390 WeakPolarHBondContact CD1-O 3.45Å; V294-L390 HydrophobicContact CB-CD2 4.29Å; V294-L390 HydrophobicContact CB-CG 4.47Å; V294-L390 HydrophobicContact CG2-CD1 4.21Å; V294-L390 HydrophobicContact CG2-CD2 3.74Å; V294-L390 HydrophobicContact CG2-CG 3.71Å; M386-L390 WeakPolarHBondContact O-CG 3.3Å; M386-L390 PolarHBondContact O-N 2.84Å; E387-L390 PolarHBondContact O-N 3.09Å; N388-L390 VanDerWaalsContact C-N 3.33Å; N388-L390 PolarHBondContact O-N 3.29Å
391A93.6Very high93.8Very high62 Ų6263 Ų6351%0.51233%0.326SS..Hα-helixtrans-99.9-43.1179.900000113.1E387 N388 I389E387-A391 VanDerWaalsContact O-CB 3.3Å; E387-A391 WeakPolarHBondContact O-CB 3.33Å; E387-A391 PolarHBondContact O-N 2.77Å; N388-A391 PolarHBondContact O-N 2.58Å; N388-A391 VanDerWaalsContact O-N 3.1Å; I389-A391 PolarHBondContact O-N 3.42Å
392V93.3Very high93.7Very high75 Ų7560.7 Ų60.746%0.45532%0.317SS..Hα-helixtrans-121.2-0.8-171.2-52.40000114.2N388 Q395N388-V392 VanDerWaalsContact O-CG2 3.31Å; N388-V392 WeakPolarHBondContact O-CG2 3.16Å; N388-V392 PolarHBondContact O-N 3.45Å; N388-V392 WeakPolarHBondContact OD1-CG2 3.49Å; V392-Q395 PolarHBondContact O-NE2 3.42Å; V392-Q395 VanDerWaalsContact O-NE2 3.09Å
393G93.1Very high93.7Very high7 Ų761.4 Ų61.47%0.07232%0.319CS..  trans79.3-177.2179.900000114.5I389 Q395I389-G393 WeakPolarHBondContact O-CA 3.44Å; I389-G393 PolarHBondContact O-N 3.41Å; G393-Q395 PolarHBondContact O-N 3.47Å
394V91.6Very high93.7Very high42 Ų4261.3 Ų61.326%0.25532%0.319SS..  trans-85.4109.5177.8-176.60000109.9P292 V312 V314 I389 P397 Y400P292-V394 HydrophobicContact CB-CG2 4.32Å; P292-V394 HydrophobicContact CG-CG2 3.9Å; V312-V394 HydrophobicContact CG1-CG2 4.14Å; V314-V394 HydrophobicContact CG1-CG1 4.18Å; V314-V394 HydrophobicContact CG1-CG2 4.41Å; I389-V394 HydrophobicContact CG2-CG2 4.06Å; V394-P397 HydrophobicContact CG1-CB 4.09Å; V394-P397 HydrophobicContact CG1-CG 3.91Å; V394-Y400 HydrophobicContact CG1-CD2 3.7Å; V394-Y400 HydrophobicContact CG1-CE2 3.86Å
395Q89.1Confident93.8Very high148 Ų14854 Ų5469%0.69229%0.289SS*.SBendtrans-85-41.5178.3-61.6-63.2-42.900112.4V392 G393V392-Q395 PolarHBondContact O-NE2 3.42Å; V392-Q395 VanDerWaalsContact O-NE2 3.09Å; G393-Q395 PolarHBondContact O-N 3.47Å
396Q91.4Very high93.9Very high122 Ų12253.2 Ų53.257%0.5729%0.287SS*.  trans-125.694.3178.3-66.2-173.39.800108.7D398 D399 Y400Q396-D398 PolarHBondContact O-N 3.46Å; Q396-D399 WeakPolarHBondContact CB-OD2 2.95Å; Q396-D399 WeakPolarHBondContact O-CB 2.81Å; Q396-D399 PolarHBondContact O-N 3.02Å; Q396-D399 PolarHBondContact OE1-OD2 3.07Å; Q396-Y400 WeakPolarHBondContact O-CD2 3.36Å
397P90.9Very high94Very high56 Ų5653.4 Ų53.436%0.36429%0.288SS..G310 helixtrans-58.9-32.4-176-26.535000114.4V314 V394 D399 Y400V314-P397 HydrophobicContact CB-CB 4.2Å; V314-P397 HydrophobicContact CG1-CB 4.3Å; V394-P397 HydrophobicContact CG1-CB 4.09Å; V394-P397 HydrophobicContact CG1-CG 3.91Å; P397-D399 PolarHBondContact O-N 3.14Å; P397-Y400 PolarHBondContact O-N 3.15Å
398D92.3Very high94.1Very high117 Ų11750.7 Ų50.763%0.62628%0.275SS*.G310 helixtrans-63.3-23.7-179.8-68.5-27000112.8Q396 Y400 V401Q396-D398 PolarHBondContact O-N 3.46Å; D398-Y400 PolarHBondContact O-N 2.91Å; D398-V401 WeakPolarHBondContact O-CG2 3.4Å
399D91.9Very high94.3Very high94 Ų9450.5 Ų50.550%0.50327%0.272SS..G310 helixtrans-69.7-15.8176.3-67.2-12.3000112.6Q396 P397Q396-D399 WeakPolarHBondContact CB-OD2 2.95Å; Q396-D399 WeakPolarHBondContact O-CB 2.81Å; Q396-D399 PolarHBondContact O-N 3.02Å; Q396-D399 PolarHBondContact OE1-OD2 3.07Å; P397-D399 PolarHBondContact O-N 3.14Å
400Y94.1Very high94.5Very high42 Ų4254.3 Ų54.317%0.16529%0.289CS..G310 helixtrans-113.7-1.4-173.4-57-71.2000113.9M386 I389 V394 Q396 P397 D398 N402 L403M386-Y400 HydrophobicContact CE-CE1 4.25Å; I389-Y400 HydrophobicContact CD1-CD1 3.74Å; I389-Y400 HydrophobicContact CD1-CE1 3.23Å; I389-Y400 HydrophobicContact CD1-CE2 4.2Å; I389-Y400 HydrophobicContact CD1-CG 4.4Å; I389-Y400 VanDerWaalsContact CD1-CZ 3.46Å; I389-Y400 HydrophobicContact CG1-CE1 4.03Å; V394-Y400 HydrophobicContact CG1-CD2 3.7Å; V394-Y400 HydrophobicContact CG1-CE2 3.86Å; Q396-Y400 WeakPolarHBondContact O-CD2 3.36Å; P397-Y400 PolarHBondContact O-N 3.15Å; D398-Y400 PolarHBondContact O-N 2.91Å; Y400-N402 PolarHBondContact O-N 3.38Å; Y400-L403 HydrophobicContact CD1-CD1 4.4Å; Y400-L403 HydrophobicContact CD1-CD2 4.13Å; Y400-L403 VanDerWaalsContact O-CB 3.29Å; Y400-L403 WeakPolarHBondContact O-CB 3.37Å; Y400-L403 PolarHBondContact O-N 2.93Å; Y400-L403 VanDerWaalsContact O-N 3.09Å
401V94.9Very high94.6Very high20 Ų2054.1 Ų54.112%0.12129%0.289CS..THydrogen-bonded Turntrans-63.5-25-176.4-60.90000113.7V314 R318 D398V314-V401 HydrophobicContact CG2-CG1 4.02Å; R318-V401 PolarHBondContact N-O 3.47Å; D398-V401 WeakPolarHBondContact O-CG2 3.4Å
402N94.9Very high94.7Very high45 Ų4552.5 Ų52.524%0.24127%0.271CS..THydrogen-bonded Turntrans-114.310176-53.8-50.9000112.6R318 Y400 F404 S405 E406R318-N402 VanDerWaalsContact CD-OD1 3.27Å; R318-N402 WeakPolarHBondContact CD-OD1 2.91Å; R318-N402 PolarHBondContact NH1-OD1 2.96Å; Y400-N402 PolarHBondContact O-N 3.38Å; N402-F404 VanDerWaalsContact C-N 3.26Å; N402-F404 PolarHBondContact O-N 3.27Å; N402-F404 VanDerWaalsContact O-N 3.12Å; N402-S405 PolarHBondContact O-N 3.09Å; N402-E406 HydrophobicContact CB-CG 3.98Å; N402-E406 WeakPolarHBondContact O-CG 3.18Å; N402-E406 PolarHBondContact O-N 3.29Å
403L96.3Very high94.8Very high21 Ų2151.5 Ų51.511%0.1127%0.267CS..Hα-helixtrans-48-48.5-170.8173.566000112.7P310 V312 M386 Y400 C407P310-L403 HydrophobicContact CB-CD2 4.04Å; P310-L403 HydrophobicContact CB-CG 4.48Å; P310-L403 HydrophobicContact CG-CD1 4.1Å; P310-L403 HydrophobicContact CG-CD2 4.06Å; P310-L403 HydrophobicContact CG-CG 4Å; V312-L403 HydrophobicContact CG2-CD2 4.04Å; M386-L403 HydrophobicContact CE-CD1 3.81Å; M386-L403 HydrophobicContact CE-CD2 3.78Å; M386-L403 HydrophobicContact CE-CG 4.45Å; M386-L403 HydrophobicContact SD-CD2 3.66Å; Y400-L403 HydrophobicContact CD1-CD1 4.4Å; Y400-L403 HydrophobicContact CD1-CD2 4.13Å; Y400-L403 VanDerWaalsContact O-CB 3.29Å; Y400-L403 WeakPolarHBondContact O-CB 3.37Å; Y400-L403 PolarHBondContact O-N 2.93Å; Y400-L403 VanDerWaalsContact O-N 3.09Å; L403-C407 PolarHBondContact O-N 3.33Å; L403-C407 VanDerWaalsContact O-N 3.14Å
404F97.6Very high94.8Very high2 Ų252.1 Ų52.11%0.00927%0.27CS..Hα-helixtrans-64.9-51.7179.5-174.3-88.6000111.5V37 F297 K309 P310 F311 L320 T323 N402 E406 C407 V408V37-F404 HydrophobicContact CB-CE1 4.27Å; V37-F404 HydrophobicContact CB-CZ 3.81Å; V37-F404 HydrophobicContact CG1-CE1 4.25Å; V37-F404 HydrophobicContact CG1-CE2 4Å; V37-F404 HydrophobicContact CG1-CZ 3.7Å; V37-F404 HydrophobicContact CG2-CZ 4.11Å; F297-F404 HydrophobicContact CB-CE2 4.06Å; K309-F404 HydrophobicContact CB-CD2 3.79Å; K309-F404 HydrophobicContact CB-CE2 3.53Å; K309-F404 HydrophobicContact CB-CZ 4.2Å; K309-F404 HydrophobicContact CD-CE2 4.39Å; K309-F404 HydrophobicContact CD-CZ 4.22Å; P310-F404 WeakPolarHBondContact O-CA 3.45Å; F311-F404 HydrophobicContact CB-CD2 4.32Å; F311-F404 HydrophobicContact CD2-CB 4.28Å; L320-F404 HydrophobicContact CB-CD1 4.42Å; L320-F404 HydrophobicContact CD1-CD1 3.95Å; L320-F404 HydrophobicContact CD1-CE1 4.25Å; L320-F404 HydrophobicContact CD1-CG 4.29Å; L320-F404 HydrophobicContact CD2-CB 4.06Å; L320-F404 HydrophobicContact CD2-CD1 3.92Å; L320-F404 HydrophobicContact CD2-CG 4.27Å; L320-F404 HydrophobicContact CG-CD1 4.31Å; T323-F404 HydrophobicContact CG2-CE1 3.84Å; T323-F404 HydrophobicContact CG2-CZ 4.24Å; N402-F404 VanDerWaalsContact C-N 3.26Å; N402-F404 PolarHBondContact O-N 3.27Å; N402-F404 VanDerWaalsContact O-N 3.12Å; F404-E406 VanDerWaalsContact C-N 3.34Å; F404-E406 PolarHBondContact O-N 3.3Å; F404-C407 WeakPolarHBondContact O-CB 3.49Å; F404-C407 PolarHBondContact O-N 2.85Å; F404-C407 VanDerWaalsContact O-N 3.17Å; F404-V408 HydrophobicContact CD1-CG2 3.94Å; F404-V408 HydrophobicContact CE1-CG2 3.64Å; F404-V408 HydrophobicContact CZ-CG2 4.3Å; F404-V408 WeakPolarHBondContact O-CG2 3.42Å; F404-V408 PolarHBondContact O-N 3.48Å
405S97.1Very high94.8Very high14 Ų1450.7 Ų50.710%0.09826%0.26CS..Hα-helixtrans-61.4-39.1179.5-72.20000112.5E322 N402 C407 V408 Q409E322-S405 PolarHBondContact OE2-OG 2.98Å; N402-S405 PolarHBondContact O-N 3.09Å; S405-C407 VanDerWaalsContact C-N 3.34Å; S405-C407 PolarHBondContact O-N 2.95Å; S405-V408 WeakPolarHBondContact O-CB 3.39Å; S405-V408 PolarHBondContact O-N 3.05Å; S405-Q409 WeakPolarHBondContact O-CG 3.26Å; S405-Q409 PolarHBondContact O-N 2.85Å
406E96.9Very high94.7Very high99 Ų9948.5 Ų48.546%0.46326%0.261SS..Hα-helixtrans-61.1-43.5174.8-74.1174.9-171.400111.2N402 F404 V408 Q409 E410N402-E406 HydrophobicContact CB-CG 3.98Å; N402-E406 WeakPolarHBondContact O-CG 3.18Å; N402-E406 PolarHBondContact O-N 3.29Å; F404-E406 VanDerWaalsContact C-N 3.34Å; F404-E406 PolarHBondContact O-N 3.3Å; E406-V408 VanDerWaalsContact C-N 3.33Å; E406-V408 PolarHBondContact O-N 2.96Å; E406-Q409 PolarHBondContact O-N 3.44Å; E406-Q409 VanDerWaalsContact O-N 3.14Å; E406-E410 WeakPolarHBondContact O-CG 3.39Å; E406-E410 PolarHBondContact O-N 3.06Å
407C97.8Very high94Very high5 Ų551 Ų513%0.03427%0.27CS..Hα-helixtrans-64.5-36.7175.4-160.50000112.1K309 L403 F404 S405 E410 E411K309-C407 HydrophobicContact CB-CB 4.2Å; K309-C407 HydrophobicContact CG-CB 4.04Å; L403-C407 PolarHBondContact O-N 3.33Å; L403-C407 VanDerWaalsContact O-N 3.14Å; F404-C407 WeakPolarHBondContact O-CB 3.49Å; F404-C407 PolarHBondContact O-N 2.85Å; F404-C407 VanDerWaalsContact O-N 3.17Å; S405-C407 VanDerWaalsContact C-N 3.34Å; S405-C407 PolarHBondContact O-N 2.95Å; C407-E410 PolarHBondContact O-N 2.94Å; C407-E411 PolarHBondContact O-N 3.25Å
408V97.9Very high92.6Very high0 Ų050.4 Ų50.40%027%0.265CS..Hα-helixtrans-61.1-43.8170.8176.90000111.3K309 E322 T323 L350 F404 S405 E406 E410 E411 L412K309-V408 HydrophobicContact CD-CB 4.38Å; K309-V408 HydrophobicContact CD-CG2 3.48Å; K309-V408 VanDerWaalsContact CD-CG2 3.48Å; E322-V408 HydrophobicContact CB-CB 4.37Å; E322-V408 HydrophobicContact CB-CG1 3.57Å; E322-V408 HydrophobicContact CG-CG1 4.02Å; T323-V408 HydrophobicContact CG2-CG2 4.34Å; L350-V408 HydrophobicContact CB-CG1 4.2Å; L350-V408 HydrophobicContact CD1-CG1 4.17Å; L350-V408 HydrophobicContact CD2-CG1 4.05Å; L350-V408 HydrophobicContact CD2-CG2 4.32Å; L350-V408 HydrophobicContact CG-CG1 4.35Å; F404-V408 HydrophobicContact CD1-CG2 3.94Å; F404-V408 HydrophobicContact CE1-CG2 3.64Å; F404-V408 HydrophobicContact CZ-CG2 4.3Å; F404-V408 WeakPolarHBondContact O-CG2 3.42Å; F404-V408 PolarHBondContact O-N 3.48Å; S405-V408 WeakPolarHBondContact O-CB 3.39Å; S405-V408 PolarHBondContact O-N 3.05Å; E406-V408 VanDerWaalsContact C-N 3.33Å; E406-V408 PolarHBondContact O-N 2.96Å; V408-E410 VanDerWaalsContact C-N 3.34Å; V408-E410 PolarHBondContact O-N 3.05Å; V408-E411 PolarHBondContact O-N 2.67Å; V408-L412 HydrophobicContact CG1-CD1 4.12Å; V408-L412 HydrophobicContact CG1-CG 4.34Å; V408-L412 VanDerWaalsContact O-CG 3.31Å; V408-L412 WeakPolarHBondContact O-CG 3.46Å; V408-L412 PolarHBondContact O-N 3.32Å
409Q97.2Very high92.7Very high87 Ų8747.1 Ų47.141%0.40725%0.247SC..Hα-helixtrans-66.5-35.8178.3-64.8-58.2-30.600112.3E322 S405 E406 S413E322-Q409 PolarHBondContact OE1-NE2 3.07Å; S405-Q409 WeakPolarHBondContact O-CG 3.26Å; S405-Q409 PolarHBondContact O-N 2.85Å; E406-Q409 PolarHBondContact O-N 3.44Å; E406-Q409 VanDerWaalsContact O-N 3.14Å; Q409-S413 WeakPolarHBondContact O-CB 3.36Å; Q409-S413 PolarHBondContact O-N 3.32Å; Q409-S413 PolarHBondContact O-OG 3.1Å
410E97.2Very high92.7Very high79 Ų7944.6 Ų44.637%0.36923%0.233SC..Hα-helixtrans-63.4-43.8172.4-71.9177.6171.700111.1L378 E406 C407 V408 S413 V414L378-E410 HydrophobicContact CD1-CB 3.7Å; L378-E410 HydrophobicContact CD1-CG 4.45Å; L378-E410 WeakPolarHBondContact CD1-OE2 3.48Å; L378-E410 HydrophobicContact CD2-CB 4.1Å; E406-E410 WeakPolarHBondContact O-CG 3.39Å; E406-E410 PolarHBondContact O-N 3.06Å; C407-E410 PolarHBondContact O-N 2.94Å; V408-E410 VanDerWaalsContact C-N 3.34Å; V408-E410 PolarHBondContact O-N 3.05Å; E410-S413 WeakPolarHBondContact O-CB 2.87Å; E410-S413 PolarHBondContact O-N 2.96Å; E410-V414 PolarHBondContact O-N 3.42Å
411E97.5Very high92.6Very high0 Ų044.7 Ų44.70%024%0.237CC..Hα-helixtrans-61.2-47.8174.5176.6171.4-156.100112.1V307 K309 L350 L375 L378 C407 V408 S413 V414 Y415V307-E411 HydrophobicContact CG2-CG 4.39Å; K309-E411 IonicContact NZ-OE1 3.26Å; K309-E411 IonicContact NZ-OE2 2.68Å; K309-E411 PolarHBondContact NZ-OE2 3.28Å; L350-E411 HydrophobicContact CD1-CG 4.36Å; L375-E411 HydrophobicContact CD2-CG 4.08Å; L378-E411 HydrophobicContact CD2-CB 3.94Å; C407-E411 PolarHBondContact O-N 3.25Å; V408-E411 PolarHBondContact O-N 2.67Å; E411-S413 PolarHBondContact O-N 2.97Å; E411-V414 WeakPolarHBondContact O-CA 3.37Å; E411-V414 WeakPolarHBondContact O-CB 3.39Å; E411-V414 PolarHBondContact O-N 3.46Å; E411-Y415 HydrophobicContact CG-CD1 4.39Å; E411-Y415 HydrophobicContact CG-CE1 3.73Å; E411-Y415 HydrophobicContact CG-CE2 3.97Å; E411-Y415 VanDerWaalsContact CG-CZ 3.49Å; E411-Y415 WeakPolarHBondContact O-CD1 3.44Å; E411-Y415 PolarHBondContact O-N 2.92Å; E411-Y415 PolarHBondContact OE1-OH 3.34Å
412L96Very high92.5Very high28 Ų2846.2 Ų46.215%0.14724%0.244CC..Hα-helixtrans-59.9-32.3175-70.4176.7000112.4L350 K353 V408 Y415 S416L350-L412 HydrophobicContact CD1-CD2 3.87Å; L350-L412 HydrophobicContact CD1-CG 4.26Å; K353-L412 HydrophobicContact CB-CD2 3.76Å; K353-L412 HydrophobicContact CG-CD2 3.77Å; V408-L412 HydrophobicContact CG1-CD1 4.12Å; V408-L412 HydrophobicContact CG1-CG 4.34Å; V408-L412 VanDerWaalsContact O-CG 3.31Å; V408-L412 WeakPolarHBondContact O-CG 3.46Å; V408-L412 PolarHBondContact O-N 3.32Å; L412-Y415 HydrophobicContact CD2-CD2 4Å; L412-Y415 HydrophobicContact CD2-CE2 4.4Å; L412-Y415 PolarHBondContact O-N 3.29Å; L412-S416 PolarHBondContact O-N 3.39Å; L412-S416 VanDerWaalsContact O-N 3.13Å; L412-S416 PolarHBondContact O-OG 3.47Å
413S94.9Very high92.3Very high53 Ų5346.3 Ų46.337%0.37124%0.244SC..Hα-helixtrans-70.5-35.5174.6-62.80000112.1Q409 E410 E411 S416 K417Q409-S413 WeakPolarHBondContact O-CB 3.36Å; Q409-S413 PolarHBondContact O-N 3.32Å; Q409-S413 PolarHBondContact O-OG 3.1Å; E410-S413 WeakPolarHBondContact O-CB 2.87Å; E410-S413 PolarHBondContact O-N 2.96Å; E411-S413 PolarHBondContact O-N 2.97Å; S413-S416 PolarHBondContact O-N 3.37Å; S413-K417 WeakPolarHBondContact O-CD 3.4Å; S413-K417 VanDerWaalsContact O-CG 3.24Å; S413-K417 WeakPolarHBondContact O-CG 3.45Å; S413-K417 PolarHBondContact O-N 2.9Å
414V93.9Very high92.1Very high21 Ų2147.9 Ų47.913%0.12725%0.253CS..Hα-helixtrans-62-49.2171173.80000109.5N374 L375 E410 E411 S416 K417 T418N374-V414 HydrophobicContact CB-CG1 3.66Å; N374-V414 HydrophobicContact CB-CG2 4.47Å; L375-V414 HydrophobicContact CD2-CB 4.1Å; L375-V414 HydrophobicContact CD2-CG1 3.79Å; L375-V414 HydrophobicContact CG-CG1 4.27Å; E410-V414 PolarHBondContact O-N 3.42Å; E411-V414 WeakPolarHBondContact O-CA 3.37Å; E411-V414 WeakPolarHBondContact O-CB 3.39Å; E411-V414 PolarHBondContact O-N 3.46Å; V414-S416 PolarHBondContact O-N 2.87Å; V414-S416 VanDerWaalsContact O-N 3.17Å; V414-K417 PolarHBondContact O-N 2.8Å; V414-K417 VanDerWaalsContact O-N 3.11Å; V414-T418 PolarHBondContact O-N 3.06Å; V414-T418 PolarHBondContact O-OG1 3.19Å; V414-T418 VanDerWaalsContact O-OG1 3.09Å
415Y91.3Very high91.7Very high12 Ų1251.2 Ų51.25%0.04727%0.271CS..Hα-helixtrans-56-34.7179.3-63.7-10.4000113.2L350 K353 H354 I357 L375 E411 L412 T418L350-Y415 HydrophobicContact CD1-CE2 4Å; K353-Y415 HydrophobicContact CB-CD2 3.79Å; K353-Y415 HydrophobicContact CB-CE2 4.22Å; H354-Y415 HydrophobicContact CB-CE2 4.22Å; H354-Y415 PolarHBondContact ND1-OH 3.49Å; I357-Y415 HydrophobicContact CB-CD1 4.26Å; I357-Y415 HydrophobicContact CB-CE1 4.33Å; I357-Y415 HydrophobicContact CB-CG 4.48Å; I357-Y415 HydrophobicContact CD1-CD1 4.19Å; I357-Y415 HydrophobicContact CD1-CG 4.08Å; I357-Y415 HydrophobicContact CG1-CD1 3.72Å; I357-Y415 HydrophobicContact CG1-CD2 3.94Å; I357-Y415 HydrophobicContact CG1-CE1 4.24Å; I357-Y415 HydrophobicContact CG1-CE2 4.4Å; I357-Y415 HydrophobicContact CG1-CG 3.55Å; I357-Y415 HydrophobicContact CG2-CD1 3.96Å; I357-Y415 HydrophobicContact CG2-CE1 3.91Å; L375-Y415 HydrophobicContact CD1-CE1 4.07Å; L375-Y415 HydrophobicContact CD2-CD1 4.22Å; L375-Y415 HydrophobicContact CD2-CE1 3.7Å; L375-Y415 HydrophobicContact CG-CE1 4.49Å; E411-Y415 HydrophobicContact CG-CD1 4.39Å; E411-Y415 HydrophobicContact CG-CE1 3.73Å; E411-Y415 HydrophobicContact CG-CE2 3.97Å; E411-Y415 VanDerWaalsContact CG-CZ 3.49Å; E411-Y415 WeakPolarHBondContact O-CD1 3.44Å; E411-Y415 PolarHBondContact O-N 2.92Å; E411-Y415 PolarHBondContact OE1-OH 3.34Å; L412-Y415 HydrophobicContact CD2-CD2 4Å; L412-Y415 HydrophobicContact CD2-CE2 4.4Å; L412-Y415 PolarHBondContact O-N 3.29Å; Y415-T418 PolarHBondContact O-OG1 2.9Å
416S86Confident91.3Very high101 Ų10154.1 Ų54.171%0.70628%0.284SS*.Hα-helixtrans-82-20.4-177.4-56.40000114.1L412 S413 V414L412-S416 PolarHBondContact O-N 3.39Å; L412-S416 VanDerWaalsContact O-N 3.13Å; L412-S416 PolarHBondContact O-OG 3.47Å; S413-S416 PolarHBondContact O-N 3.37Å; V414-S416 PolarHBondContact O-N 2.87Å; V414-S416 VanDerWaalsContact O-N 3.17Å
417K78.5Confident90.8Very high176 Ų17650.3 Ų50.377%0.76527%0.269SS*.Hα-helixtrans-90-13.3-177.3-74.5170.7-174.51740113.5S413 V414S413-K417 WeakPolarHBondContact O-CD 3.4Å; S413-K417 VanDerWaalsContact O-CG 3.24Å; S413-K417 WeakPolarHBondContact O-CG 3.45Å; S413-K417 PolarHBondContact O-N 2.9Å; V414-K417 PolarHBondContact O-N 2.8Å; V414-K417 VanDerWaalsContact O-N 3.11Å
418T61.5Low90.2Very high42 Ų4254.5 Ų54.526%0.25829%0.291SS..  trans-103.10-176.342.30000110.8R367 I371 V414 Y415R367-T418 PolarHBondContact NE-O 3.42Å; R367-T418 PolarHBondContact NH2-O 2.65Å; R367-T418 PolarHBondContact NH2-OXT 3.42Å; I371-T418 HydrophobicContact CB-CG2 4.48Å; I371-T418 HydrophobicContact CD1-CG2 4.44Å; I371-T418 VanDerWaalsContact CG1-CB 3.45Å; I371-T418 HydrophobicContact CG1-CG2 3.44Å; I371-T418 VanDerWaalsContact CG1-CG2 3.44Å; V414-T418 PolarHBondContact O-N 3.06Å; V414-T418 PolarHBondContact O-OG1 3.19Å; V414-T418 VanDerWaalsContact O-OG1 3.09Å; Y415-T418 PolarHBondContact O-OG1 2.9Å

Retrieved 418 of 418 residues in 1120 ms (Link to these results)